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"FUTURE ANALYTICS CONSULTING LIMITED", "WOLAITA SODO UNIVERSITY"], "EU_Contribution": ["EUR 2 097 000"], "Project_Title": ["Building Resilience through Education"], "Total_Cost": ["EUR 2 097 000"], "Country": ["Ireland", "Ireland", "Belgium", "Ireland", "Ethiopia"], "Project_ACR": ["BRTE"], "Technology_Description": "The Building Resilience Through Education (BRTE) Consortium brings together partners from academia, the private sector and the NGO sector to find innovative ways to strengthen the resilience of communities affected by recurring disasters. This project has its origins in an ex-post impact evaluation of Concern Worldwide\u2019s twenty-five year engagement in Wolaita, Ethiopia. Conducted by University College Dublin\u2019s Centre for Humanitarian Action in collaboration with Wolaita Sodo University, the evaluation found that, despite significant improvements in communities\u2019 capacities to both absorb the effects of recurring disasters and to adapt their livelihoods based on experience of recent disasters, they remain extremely vulnerable to their natural and environmental context. As a result there is an urgent need for a novel approach that moves beyond supporting the mere absorption of or adaptation to recurring shocks and that transforms the capacity of exposed communities. The BRTE partnership has identified the importance of education in bringing about this transformative change. It aim is to build the capacity of Wolaita\u2019s educational institution in pursuit of the following objectives:", "To": ["2021-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Other", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["778196"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["UPPSALA UNIVERSITET", "SITEX 45 SRL", "INSTITUT PASTEUR DE TUNIS", "UNIVERSIDAD COMPLUTENSE DE MADRID", "UNIVERSITATEA SPIRU HARET", "ELVESYS SAS", "UNITED STATES DEPARTMENT OF AGRICULTURE", "UNIVERSIDAD DE PAMPLONA"], "EU_Contribution": ["EUR 1 395 000"], "Project_Title": ["Volatolomics test for the diagnosis of bovine tuberculosis"], "Total_Cost": ["EUR 1 404 000"], "Country": ["Sweden", "Romania", "Tunisia", "Spain", "Romania", "France", "United States", "Colombia"], "Project_ACR": ["bTB-Test"], "Technology_Description": "Bovine tuberculosis, caused by Mycobacterium bovis and other members of the M. tuberculosis complex, is a serious global disease with significant impact on animal health, public health, and international trade. This study will focus on investigating the feasibility of a non-invasive methodology for the diagnosis of bovine tuberculosis in cattle. Our approach will be based on the detection via volatile organic compounds of the disease fingerprint in several non-invasive samples, employing analytical methods and chemical sensing devices.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["777832"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA", "ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA"], "EU_Contribution": ["EUR 149 937,50"], "Project_Title": ["Luminescent silicon nanocrystals as bioimaging systems"], "Total_Cost": ["EUR 149 937,50"], "Country": ["Italy", "Italy"], "Project_ACR": ["SiNBioSys"], "Technology_Description": "Optical imaging is a powerful tool for light-guided surgery and for the study of biological functions via dynamic visualization of processes in tissues and cells. Most of optical imaging techniques utilise fluorescent probes that can suffer from low contrast, due to scattering of the excitation light, and low tissue penetration. Silicon nanocrystals (SiNCs), developed within the ERC PhotoSi project, are a very promising alternative for this purpose: silicon is essentially non-toxic, easily available, and it can be covalently linked with dyes. The result is a highly-robust and biocompatible hybrid material, which exhibits colour tunability across the visible and near-infrared region. On top of that, the extraordinary brightness of the material coupled to a long-lived luminescence (lifetime of the hundreds of microseconds) enables time-gated detection. Therefore, SiNBioSys technology greatly improves the contrast of the obtained images with a low-cost equipment and with a material based on abundant and biocompatible elements (Si, C, O, H). An international patent application on the key underlying technology was filed in 2015 and subsequently nationalized in the primary markets (Europe and USA). Based on these premises, this proposal is intended to gather sufficient technical and commercial evidence to make the SiNBioSys technology attractive for further investment in the development of a new commercial product by: (i) optimization and validation of SiNCs against current gold standards; (ii) an in-depth market analysis; (iii) a realistic business development strategy with demonstrations to leading companies in the field. The proposed technology will thus bring an economic impact, as well as social benefits: it will demonstrate its ability to replace currently used expensive setups and will enable innovative imaging tools for early diagnosis of diseases, particularly in the field of cancer and neuroscience.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["780061"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["UNIWERSYTET WARSZAWSKI", "UNIWERSYTET IM. ADAMA MICKIEWICZA W POZNANIU", "RIJKSUNIVERSITEIT GRONINGEN", "STICHTING FRYSKE AKADEMY", "UNIVERSITEIT LEIDEN", "STOWARZYSZENIE NA RZECZ ZACHOWANIA DZIEDZICTWA KULTUROWEGO MIASTA WILAMOWICE WILAMOWIANIE", "GRUPPO DI AZIONE LOCALE LO SVILUPPORURALE DELL'AREA GRECANICA SCARL", "LATGOLYS STUDENTU CENTRS", "THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL", "THE UNIVERSITY OF TEXAS SYSTEM", "YALE UNIVERSITY", "ARENET", "INSTITUTO DE DOCENCIA E INVESTIGACION ETNOLOGICA DE ZACATECAS AC", "SMITHSONIAN INSTITUTION"], "EU_Contribution": ["EUR 1 579 500"], "Project_Title": ["Minority Languages, Major Opportunities.Collaborative Research, Community Engagement and Innovative Educational Tools"], "Total_Cost": ["EUR 1 687 500"], "Country": ["Poland", "Poland", "Netherlands", "Netherlands", "Netherlands", "Poland", "Italy", "Latvia", "United States", "United States", "United States", "Mexico", "Mexico", "United States"], "Project_ACR": ["COLING"], "Technology_Description": "The linguistic and cultural diversity of Europe is crucial to the capacity for problem solving and creative thinking upon which our general wellbeing and economic prosperity depend in an increasingly global and technological society. However, language diversity and immigration are often seen as threats and are challenged by discriminatory attitudes and state policies. COLING will provide justification for the strengthening and revitalization of minority languages, as well as guidelines to implement concrete programs for this purpose. The project\u2019s objectives focus on developing and sharing expert knowledge on language revitalization programs that combine community-driven and top-down approaches; promoting engaged collaboration among academic, nonprofit and community-based institutions; developing efficient teaching methodologies, teacher training, and curricula for minority languages; establishing a new international academic program in minority studies at the partner institutions, in which the new methodologies and curricula will be employed. To this end, COLING affiliated researchers will work together to a) document and archive linguistic-cultural diversity and language practices of indigenous communities and migrants; b) explore the Trans-Atlantic perspectives and historical ties between the Americas and Europe that demonstrate the cultural resilience of indigenous peoples and the evolution of heritage cultures in mixed societies; c) develop innovative teaching methodologies through content modules in textual and digital formats and d) investigate the causative and correlative relationships between language identities, linguistic and cultural discrimination, self-confidence, trauma and well-being, and social cohesion in multilingual and multicultural contexts. COLING will organize summer schools, workshops, trainings to bring together researchers, practitioners and community members, permitting the exchange of skills, best practices and research results.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Poland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Other"], "From": ["2018-01-01"], "Project_ID": ["778384"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["CIIMAR - Centro Interdisciplinar de Investiga\u00e7\u00e3o Marinha e Ambiental", "UNIVERSIDAD DE SANTIAGO DE COMPOSTELA", "Q TECHNOLOGIES LTD", "UNIVERSITA DEGLI STUDI DI TRIESTE", "THE QUEEN'S UNIVERSITY OF BELFAST", "MARINE BIOLOGICAL ASSOCIATION OF THE UNITED KINGDOM", "INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER", "AGUAS DE GAIA EM SA", "Institut National des Sciences et Technologies de la Mer", "APPLIED GENOMICS LTD", "E&H SERVICES AS", "NATURAL BIOTEC SL", "UNIVERSIDADE DE CABO VERDE", "UNIVERSITE CHOUAIB DOUKKALI"], "EU_Contribution": ["EUR 702 000"], "Project_Title": ["Emergent Marine Toxins in the North Atlantic and Mediterranean: New Approaches to Assesstheir Occurrence and Future Scenarios in the Framework of Global Environmental Changes."], "Total_Cost": ["EUR 702 000"], "Country": ["Portugal", "Spain", "United Kingdom", "Italy", "United Kingdom", "United Kingdom", "France", "Portugal", "Tunisia", "United Kingdom", "Czech Republic", "Spain", "Cape Verde", "Morocco"], "Project_ACR": ["EMERTOX"], "Technology_Description": "EMERTOX aims at mapping the actual situation in emergent marine toxins and the producing organisms, developing new approaches to assess their occurrence and predicting the possible future scenarios in the framework of global warming. The partnership, formed by a multidisciplinary team, will produce a joint research and innovation project that will exploit the complementary expertise of the participants and will create synergies among them. The main objectives are:", "To": ["2022-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Portugal"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["778069"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["UNIVERSITA TA MALTA", "UNIVERSITY OF LEICESTER", "NOVA ID FCT - ASSOCIACAO PARA A INOVACAO E DESENVOLVIMENTO DA FCT", "UNIVERSITY OF KENT", "AALBORG UNIVERSITET", "UNIVERSITY OF GLASGOW", "IT-UNIVERSITETET I KOBENHAVN", "ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA", "UNIVERSITA DEGLI STUDI DI TORINO", "ACTYX AG", "BITLAND SRL", "IXARIS SYSTEMS (MALTA) LIMITED", "GREEN BY WEB LDA", "COMUNE DI TORINO", "XIBIS LIMITED", "EXFORMATICS AS", "MAIDSAFE.NET LIMITED", "CARNEGIE MELLON UNIVERSITY", "UNIVERSIDAD DE BUENOS AIRES", "THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS", "MCAFEE ARGENTINA S.A."], "EU_Contribution": ["EUR 630 000"], "Project_Title": ["Behavioural Application Program Interfaces"], "Total_Cost": ["EUR 742 500"], "Country": ["Malta", "United Kingdom", "Portugal", "United Kingdom", "Denmark", "United Kingdom", "Denmark", "Italy", "Italy", "Germany", "Italy", "Malta", "Portugal", "Italy", "United Kingdom", "Denmark", "United Kingdom", "United States", "Argentina", "United States", "Argentina"], "Project_ACR": ["BEHAPI"], "Technology_Description": "APIs are typically flat structures, i.e. sets of service/method signatures specifying the expected service parameters and the kind of results one should expect in return. However, correct API usage also requires the individual services to be invoked in a specific order. Despite its importance, the latter information is either often omitted, or stated informally via textual descriptions. Behavioural Types are a suite of technologies that formalise of this information, elevating flat API descriptions to a graph structure of services. This permits automated analyses for correct API compositions so as to provide guarantees such as service compliance, deadlock freedom, dynamic adaptation in the presence of failure, load balancing etc. The proposed project aims to bring the existing prototype tools based on these technologies to mainstream programming languages and development frameworks used in industry.", "To": ["2022-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Malta"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-03-01"], "Project_ID": ["778233"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["UNIVERSIDADE DE EVORA", "UNIVERSIDADE NOVA DE LISBOA", "INSTITUTO DE CIENCIAS SOCIAIS", "INSTITUTO UNIVERSITARIO DE LISBOA", "UNIVERSIDAD DE CANTABRIA", "UNIVERSIDAD DE SANTIAGO DE COMPOSTELA", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE", "BROWN UNIVERSITY", "UNIVERSIDADE DE CABO VERDE", "UNIVERSIDADE FEDERAL DA BAHIA", "UNIVERSIDAD NACIONAL DE LA PLATA", "EL COLEGIO DE MICHOACAN"], "EU_Contribution": ["EUR 1 030 500"], "Project_Title": ["Rebellion and Resistance in the Iberian Empires, 16th-19th centuries"], "Total_Cost": ["EUR 1 030 500"], "Country": ["Portugal", "Portugal", "Portugal", "Portugal", "Spain", "Spain", "Germany", "Chile", "United States", "Cape Verde", "Brazil", "Argentina", "Mexico"], "Project_ACR": ["RESISTANCE"], "Technology_Description": "Economic inequalities, social exclusion, discrimination against minorities, cultural resistance and disruption of social cohesion \u2013 these are all key concerns in the current European and global agenda, both in scholarly work and policy-making. RESISTANCE aims at analysing these issues by focusing on the processes of resistance carried out by social actors that have been historically disadvantaged, discriminated against and dominated. By using a concept of resistance that connects continued and less visible forms of resistance, cultural dissent and violent revolts, the ultimate goal of RESISTANCE is to produce a reinterpretation of the universe of \u201cthe dominated\u201d. RESISTANCE will provide an understanding of how these actors could influence processes of social change, either by opening up societies to diversity and making them more inclusive and equal, or, conversely, by causing the increase of repression.", "To": ["2022-05-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Portugal"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2018-06-01"], "Project_ID": ["778076"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA", "THE UNIVERSITY OF BIRMINGHAM", "UNIVERSITE DE MONS", "UNIVERSITA DEGLI STUDI DI GENOVA", "MASD INGENIERIA DE VALORIZACION DE RESIDUOS DE ORIGEN AGROFORESTAL", "STELLENBOSCH UNIVERSITY", "INSTITUTE OF CHEMISTRY, CHINESE ACADEMY OF SCIENCES", "THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND", "NATIONAL UNIVERSITY CORPORATION YAMAGATA UNIVERSITY", "UNIVERSIDAD SIMON BOLIVAR"], "EU_Contribution": ["EUR 1 260 000"], "Project_Title": ["SYNTHESIS, CHARACTERIZATION, STRUCTURE AND PROPERTIES OF NOVEL BIODEGRADABLE POLYESTERS"], "Total_Cost": ["EUR 1 395 000"], "Country": ["Spain", "United Kingdom", "Belgium", "Italy", "Spain", "South Africa", "China", "United States", "Japan", "Venezuela"], "Project_ACR": ["BIODEST"], "Technology_Description": "BIODEST (Synthesis, Characterization, Structure and Properties of Novel Biodegradable Polyesters) Research and Innovation Staff Exchange (RISE) project aims to strengthen around student and staff exchanges with the aim to improve skills and knowledge of the participating partners and promote collaboration between four European Research organizations: University of the Basque Country (Spain), University of Mons (Belgium), University of Genova (Italy), and University of Warwick (U.K.) and five non-EU Research Organizations: University of Tulane (USA), Chinese Academy of Science (China), Simon Bolivar University (Venezuela), University of Stellenbosch (South Africa), and Yamagata University (Japan). Moreover the non-academic European organization \u201cMa+D - Waste Valorization Engineering\u201d will collaborate in the networking activities. The project will provide support for the participating research organizations to establish or reinforce long-term research cooperation in the topic of novel biodegradable polyesters through a coordinated joint programme of exchange of researchers for short periods.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["778092"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["UNIVERSIDADE DE AVEIRO", "VRIJE UNIVERSITEIT BRUSSEL", "TECHNISCHE UNIVERSITAET DRESDEN", "KAUNO TECHNOLOGIJOS UNIVERSITETAS", "INSTITUTE OF MAGNETISM OF THE NATIONAL ACADEMY OF SCIENCE OF UKRAINE AND THE MINISTRY OF EDUCATION AND SCIENCE OF UKRAINE", "WMT WIRE MACHINE TECHNOLOGIES LTD", "SSPA SCIENTIFIC AND PRACTICAL MATERIALS RESEARCH CENTRE OF NAS OF BELARUS"], "EU_Contribution": ["EUR 558 000"], "Project_Title": ["Physical principles of the creation of novel SPINtronic materials on the base of MULTIlayered metal-oxide FILMs for magnetic sensors and MRAM"], "Total_Cost": ["EUR 558 000"], "Country": ["Portugal", "Belgium", "Germany", "Lithuania", "Ukraine", "Israel", "Belarus"], "Project_ACR": ["SPINMULTIFILM"], "Technology_Description": "The main goal of the project is the elaboration of research and development principles and technology, as well as creation of novel nanoheterostructures for application in spintronic devices, first of all, in magnetic field sensors and magnetoresistive random access memories. The key research and technological aspects are focused on the formation of layers and/or nanosized grains of a ferromagnetic material with an ultimate degree of conduction electron spin polarization, separated by dielectric interlayers. The main research, technological and innovation aspects of the work are aimed at an increase of the devices\u2019 sensitivity to magnetic fields thanks to the high degree of spin polarization and to the magnetoresistance due to electron quantum tunneling through dielectric barriers. ", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Portugal"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["778308"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["UNIVERSITE DE PICARDIE JULES VERNE", "INSTITUT JOZEF STEFAN", "NANOTECHCENTER LLC", "UNIVERSITE CADI AYYAD", "SOUTHERN FEDERAL UNIVERSITY"], "EU_Contribution": ["EUR 837 000"], "Project_Title": ["Engineering of Nanostructures with Giant Magneto-Piezoelectric and Multicaloric Functionalities"], "Total_Cost": ["EUR 936 000"], "Country": ["France", "Slovenia", "Ukraine", "Morocco", "Russia"], "Project_ACR": ["ENGIMA"], "Technology_Description": "Nowadays smart materials play a crucial role in the next-generation of intelligent devices and sensors, smart homes, autonomous devices, and robotics. Nanostructuring materials open up new horizons bringing in their multifunctionality and reduce the energy consumption. This reveals new scientific avenues and paves ways for breakthroughs in technology. Realization of structured materials with the strong coupling of electric and magnetic order and large multicaloric properties is a milestone for modern electronics and the gate for fascinating applications. In this context, we develop the partnership within the RISE consortium ENGIMA, involving the academic partners from two EU Member States, France and Slovenia Third Countries Universities in Morocco and Russia the non-academic SME from Associated Country, Ukraine. The network combines the complementary interdisciplinary and intersectoral expertise with established collaboration between partners and clear potential for skills transfer and exchange of knowledge, extended from fundamental to applied physics and from material chemistry to industrial nanotechnologies. Consortium defined a research objective of exploring the nanostructures in a form of tethered magnetic 1-D/piezoelectric nanostructures and magnetic/piezoelectric superlattices to obtain new ferroic materials with giant magnetoelectric and multicaloric functionalities that have potential applications as magnetoelectric sensors and, telecommunication devices. This task will be achieved by joining the efforts through the staff exchange, sharing knowledge, innovation and by multidisciplinary training of the team of collaborating young researchers able to conduct the research and exploit its application to this new area.", "To": ["2021-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["778072"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["INSTYTUT NISKICH TEMPERATUR I BADAN STRUKTURALNYCH IM. WLODZIMIERZA TRZEBIATOWSKIEGO POLSKIEJ AKADEMII NAUK", "VILNIAUS UNIVERSITETAS", "UNIVERSIDADE DE AVEIRO", "HELMHOLTZ-ZENTRUM GEESTHACHT ZENTRUM FUR MATERIAL- UND KUSTENFORSCHUNG GMBH", "INSTITUTE OF PHYSICS OF NATIONAL ACADEMY OF SCIENCE OF UKRAINE", "NANOCERAMICS SPOLKA AKCYJNA", "FRANCISK SKORINA GOMEL STATE UNIVERSITY", "SSPA SCIENTIFIC AND PRACTICAL MATERIALS RESEARCH CENTRE OF NAS OF BELARUS"], "EU_Contribution": ["EUR 783 000"], "Project_Title": ["Transition metal oxides with metastable phases: a way towards superior ferroic properties"], "Total_Cost": ["EUR 783 000"], "Country": ["Poland", "Lithuania", "Portugal", "Germany", "Ukraine", "Poland", "Belarus", "Belarus"], "Project_ACR": ["TransFerr"], "Technology_Description": "The main objective of the project is development of complex transition metal oxides with perovskite-like structure having improved and controllable (multi)ferroic properties. The mentioned materials are manganites and ferrites with optimal composition having distinct magnetization, polarization, (magneto)transport properties or magnetoelectric coupling. The idea of the project is to utilize reduced structural stability of these oxides which increases their sensitivity to external stimuli. Improved functional properties of these oxides can be controlled via modification of the chemical bond character, structural parameters, stoichiometry, defects etc. The reduced stability is associated with the metastable structural state formed in the vicinity of the phase boundaries, while this state presumably consists of coexistent nanoscale regions of the adjacent structural phases. There are two ideas to create metastable state: the first one \u2013 to design ceramics via chemical substitution and post-synthesis treatment by high pressure and/or thermal cycling in gases to induce nanoscale regions, the second one assumes chemical routes synthesis of films and ceramics. Besides the fundamental interest of the phase transitions and related phenomena affecting properties of the oxides the applicants consider them to be effective materials for electronic applications (as sensors, magnetic memory elements, filters etc.). Research of these oxides requires consolidative efforts of specialists in different scientific areas - Materials Science, Theoretical Physics, Solid State Physics etc. as well as an access to unique equipment and facilities. Another important objective of the project is a formation of interdisciplinary network of teams and specialists with different scientific backgrounds which will ensure effective transfer of actual knowledge and skills. Development of the transition metal oxides with controllable properties has promising commercial opportunities for the involved SME.", "To": ["2021-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Poland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2017-12-01"], "Project_ID": ["778070"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["OCEAN SENTINEL"], "Total_Cost": ["EUR 150 000"], "Country": ["France", "France"], "Project_ACR": ["OCEAN SENTINEL"], "Technology_Description": "Fisheries are operating worldwide over nation\u2019s Economic Exclusive Zones (EEZ) as well as over international waters. Information on the location of fishing is rarely known, especially in international waters, yet it is critical since in many oceanic sectors non declared and illegal fisheries are affecting negatively ecosystems through over exploitation and by catch of non-target species Knowledge about the distribution of fishing boats is fundamental for the regulation of fishing activities as well for the conservation of the oceans. I propose a New Concept of ocean surveillance based on new bio-logging technologies fitted on large foraging marine predators. The OCEAN SENTINEL Proof of this Concepts will (1) develop a logger called CENTURION that couple a XGPS platform detecting and locating radar emissions, with a satellite transmission system (Argos) that would send instantaneously the location of vessels to a receiving site, (2) deploy the logger on wide ranging animals used as platforms and (3) make available immediately the information obtained from the CENTURION logger through a website. The OCEAN SENTINEL programme will generate important social benefits by providing information to a wide range of beneficiaries, from governments or regional authorities managing EEZ and natural resources, regional or national fishing authorities, researchers and non-governmental organisation in conservation. The concept will be tested in the Southern Indian Ocean from Crozet and Kerguelen Islands where valuable and extensive fisheries operate in EEZs and over oceanic waters. This concept has the potential to be used in other areas where information on fisheries location is needed. The project will also lead to further discoveries on the relationship between seabirds and fisheries as well on the extent of fisheries in zones where surveillance by conventional methods is not possible.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["780058"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["NOVA ID FCT - ASSOCIACAO PARA A INOVACAO E DESENVOLVIMENTO DA FCT", "DANMARKS TEKNISKE UNIVERSITET", "UNIVERSIDAD DE MALAGA", "ECO RECYCLING SOCIETA A RESPONSABILITA LIMITATA", "AMPHOS 21 CONSULTING SL", "E-MINES", "LOMARTOV SL", "NORTHEASTERN UNIVERSITY", "LEHIGH UNIVERSITY CORPORATION"], "EU_Contribution": ["EUR 693 000"], "Project_Title": ["Thinking rough towards sustainability"], "Total_Cost": ["EUR 733 500"], "Country": ["Portugal", "Denmark", "Spain", "Italy", "Spain", "France", "Spain", "United States", "United States"], "Project_ACR": ["e.THROUGH"], "Technology_Description": "To tackle its critical raw material (CRM) dependency, Europe needs comprehensive strategies based on sustainable primary mining, recovery from secondary resources and recycling. The EC classified 20 CRMs due to their high economic importance and high risk of supply interruption. e.THROUGH has the ambitious vision of turning the challenge of CRMs dependence into a strategic strength for Europe, contributing towards declassifying some CRMs, as tungsten, indium, gallium and chromium, by: 1) Promoting new trends in the characterization and exploration of mineral deposits; 2) Mapping CRMs between EU mining regions; 3) Gaining knowledge on innovative processes for recovery secondary CRMs; 4) Redesign construction materials using secondary materials, closing loops, strongly supporting waste minimization; 5) Life Cycle Assessment (LCA) for the evaluation of global environmental impacts; 6) Transferring newly generated knowledge to stakeholders, both for policy development and standardization, and for shaping responsible behaviours. e.THROUGH is an intersectoral and interdisciplinary consortium of EU & Third Country partners of leading institutions that see waste as a resource to recover CRMs, influencing the whole value chain. By training human resources in CRMs\u00b4value chain, their recovery, recycling, further reuse and LCA, they become the much needed young and senior scientists and engineers for the growing EU CRM industry. The consortium comprises 40% industry and 60% research partners. This should help push Europe to the forefront in CRM sectors, providing eco-friendly alternatives in supply. The generated scientific relevant knowledge will be transferred to shape industries, communities and individual citizens\u2019 behaviour, fostering corporate sustainability performance, important to influence economic agents\u2019 choices. e.THROUGH will generate a win-win situation for both the environment and the economy, promoting the required transition towards a sustainable society.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Portugal"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["778045"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA", "FONDAZIONE RECUPERO E VALORIZZAZIONE DELLA MEMORIA STORICA DEL CAMPO DI FOSSOLI", "UNIVERSITEIT VAN AMSTERDAM", "STICHTING CASTRUM PEREGRINI", "UNIVERSIDAD NACIONAL DE COLOMBIA", "UNIVERSIDAD DE BUENOS AIRES", "MUSEO DE SITIO ESMA - EX CENTRO CLANDESTINO DE DETENCI\u00d3N, TORTURA Y EXTERMINIO"], "EU_Contribution": ["EUR 553 500"], "Project_Title": ["Questioning Traumatic Heritage: Spaces of Memory in Europe, Argentina, Colombia"], "Total_Cost": ["EUR 553 500"], "Country": ["Italy", "Italy", "Netherlands", "Netherlands", "Colombia", "Argentina", "Argentina"], "Project_ACR": ["SPEME"], "Technology_Description": "SPEME will develop a joint program of exchanges between academic researchers - working on memory, trauma and heritage - and non-academic professionals - working in the fields of memory museums and sites of memory - between Italy, The Netherlands, Argentina and Colombia. ", "To": ["2022-06-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Other", "Higher or Secondary Education Establishments", "Other", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2018-07-01"], "Project_ID": ["778044"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI TRENTO", "UNIVERSIDADE DO MINHO", "CHONBUK NATIONAL UNIVERSITY", "CHULALONGKORN UNIVERSITY", "MONGOLIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY"], "EU_Contribution": ["EUR 670 500"], "Project_Title": ["Regenerative Medicine Innovation Crossing - Research and Innovation Staff Exchange inRegenerative Medicine"], "Total_Cost": ["EUR 877 500"], "Country": ["Italy", "Portugal", "South Korea", "Thailand", "Mongolia"], "Project_ACR": ["REMIX"], "Technology_Description": "Natural materials in biomedical field are investigated for clinical use, as materials for the fabrication of biomedical prostheses, for the stimulation of regenerative medicine patterns, or as carriers for drug release, and have acquired increasing relevance in the past years, being recognized their intrinsic bioactive properties and the possibility to repair and overcome diseases with the use of Tissue Engineering and Regenerative Medicine (TERM) based procedures.", "To": ["2021-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["778078"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN", "MATER MISERICORDIAE UNIVERSITY HOSPITAL LIMITED", "UNIVERSITY OF ULSTER", "UNIVERSITA DEGLI STUDI DI PADOVA", "G.TEC MEDICAL ENGINEERING GMBH", "CONGREGAZIONE DELLE SUORE INFERMIERE DELL ADDOLORATA", "EKSO BIONICS INC"], "EU_Contribution": ["EUR 144 000"], "Project_Title": ["Physiological and Rehabilitation Outcomes: Gains from Automated Interventions in stroke Therapy (PRO GAIT)"], "Total_Cost": ["EUR 157 500"], "Country": ["Ireland", "Ireland", "United Kingdom", "Italy", "Austria", "Italy", "United States"], "Project_ACR": ["PRO GAIT"], "Technology_Description": "Developments in robotics allow people with profound neuromuscular deficits after stroke to walk with assistance (during the gait cycle) using an exoskeleton robot. Integrating a robotic device with individualised user electroencephalography (EEG /electrical activity in the motor areas in the brain) and EMG (muscle)feedback would allow more physiological and targeted gait parameters in response to effort, and confer neuroplastic training effects including neuromodulation of temporal and spatial features of gait.", "To": ["2022-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Other", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-03-01"], "Project_ID": ["778043"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["BOURNEMOUTH UNIVERSITY", "UNIVERSITETET I BERGEN", "UNIVERSITY OF BRADFORD", "UNIVERSIDAD DE CANTABRIA", "UNIVERSIDAD DE SEVILLA", "UAB INDEFORM", "COMSATS INSTITUTE OF INFORMATION TECHNOLOGY", "UNIVERSITI TEKNOLOGI MALAYSIA"], "EU_Contribution": ["EUR 535 500"], "Project_Title": ["PDE-based geometric modelling, image processing, and shape reconstruction"], "Total_Cost": ["EUR 535 500"], "Country": ["United Kingdom", "Norway", "United Kingdom", "Spain", "Spain", "Lithuania", "Pakistan", "Malaysia"], "Project_ACR": ["PDE-GIR"], "Technology_Description": "Geometric modelling, image processing, and shape reconstruction have huge applications in various sectors and greatly impact on EU\u2019s economy, human health, security, entertainment and others. Existing problems such as big data and heavy manual operations in geometric modelling, incapacity in image processing in continuous domains, and lack of continuity and differentiability in shape reconstruction seriously affect quality, efficiency and capacity. Partial differential equation (PDE) based techniques provide effective solutions to these problems. Current PDE-based modelling cannot achieve both powerful capacity and high computational performance. PDE-based image processing suffers from expensive cost and local minimization. PDE-based shape reconstruction has not been developed.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["778035"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["UNIVERSITY OF NEWCASTLE UPON TYNE", "THE HEBREW UNIVERSITY OF JERUSALEM", "UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN", "UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA", "THE UNIVERSITY OF BIRMINGHAM", "QUANTUMDX GROUP LIMITED", "NATIONAL UNIVERSITY OF SINGAPORE PUBLIC COMPANY LIMITED BY GUARANTEE", "KOKURITSU DAIGAKU HOJIN HOKKAIDO DAIGAKU", "UNIVERSITY OF MELBOURNE", "BRIGHAM YOUNG UNIVERSITY NON PROFIT CORPORATION", "UNIVERSITY OF WESTERN SYDNEY"], "EU_Contribution": ["EUR 499 500"], "Project_Title": ["Molecular diagnostics through DNA modification and interfacial engineering"], "Total_Cost": ["EUR 522 000"], "Country": ["United Kingdom", "Israel", "Ireland", "Spain", "United Kingdom", "United Kingdom", "Singapore", "Japan", "Australia", "United States", "Australia"], "Project_ACR": ["DNASURF"], "Technology_Description": "DNASURF will establish a global network of excellence for exchange of research staff and transfer of knowledge, to provide high-level training and career advancement opportunities, focussed on interdisciplinary DNA technology with a view to development of innovative solutions for DNA molecular diagnostics. It brings together leading academic and commercial scientific groups from 3 European and 4 non-European countries who will study complementary aspects of DNA synthesis, DNA nanoarchitectures, DNA at surfaces, and DNA for biomedical devices. DNASURF aims to transform creative scientific ideas into innovative biomedical products and services by exploiting and integrating advances in DNA synthesis, nanotechnology, interfacial engineering, and microsystems research. The pathway from basic science to commercial applications is facilitated by collaboration between academic labs and SMEs that are at the forefront of new methodologies. The ambitious scientific objectives of DNASURF are complemented by the aim to increase cutting-edge technical knowledge and professional skills across the network through staff exchanges and training in key methods as well as commercialisation of research. A long term goal of DNASURF is to consolidate a group of collaborative young multi-disciplinary scientists that can bring about future development of disruptive technologies in the commercially important scientific field of molecular diagnostics.", "To": ["2021-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["778001"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["UNIVERSITY OF PIRAEUS RESEARCH CENTER", "UNIVERSIDAD DE MALAGA", "BEIA CONSULT INTERNATIONAL SRL", "NEUROSOFT SOFTWARE PRODUCTIONS SA"], "EU_Contribution": ["EUR 1 080 000"], "Project_Title": ["Scalable, trustEd, and interoperAble pLatform for sEcureD smart GRID"], "Total_Cost": ["EUR 1 080 000"], "Country": ["Greece", "Spain", "Romania", "Greece"], "Project_ACR": ["SealedGRID"], "Technology_Description": "The rapid evolution of ICT has revealed the potential for centrally monitoring, controlling, and optimising the power grid. In this context, a more intelligent, responsive, and efficient, system has been devised, known as the Smart Grid (SG). As explained in the EU Third Energy Package the SG will support a dynamic two-way information exchange between utility companies and their customers, contributing towards a smart and sustainable energy management in Europe and the establishment of a wiser energy consumption mentality. However, besides the benefits of such an endeavour, the power grid will be exposed to security threats inherited from the ICT sector, while privacy issues and new vulnerabilities, related to the specific characteristics of the SG infrastructure, will emerge. The problem is assessed as crucial, if we consider that a potential attack to the SG may lead to cascading failures, ranging from destruction of other interconnected critical infrastructures to loss of human lives. Thus, the development of a security platform tailored to the SG is required, that i) can efficiently manage the plethora of SG nodes, ii) deal with potential malicious hardware or software modifications due to the physical access of the customers to the SG nodes, and iii) operate over heterogeneous systems. Considering all the above, SealedGRID aims at bringing together experts from industry and academia from cross-sectorial research areas having complementary background with the long-term goal to design, analyse, and implement a scalable, highly trusted and interoperable SG security platform. The platform will combine, for the very first time, technologies like Blockchain, Distributed Hash Tables, Trusted Execution Environments, and OpenID Connect, while for its realization the SealedGRID consortium is committed to a fully-integrated and multi-disciplinary secondment programme combined with a set of networking, dissemination, and exploitation activities.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Greece"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-01-01"], "Project_ID": ["777996"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["ECOLE NATIONALE DES PONTS ET CHAUSSEES", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS", "CABLENET COMMUNICATION SYSTEMS LTD", "BLUESOFT SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA", "DELOITTE CONSULTING & ADVISORY"], "EU_Contribution": ["EUR 1 692 000"], "Project_Title": ["A Framework for Pairing Circular Economy and IoT: IoT as an enabler of the Circular Economy circularity-by-design as an enabler for IoT (CE-IoT)"], "Total_Cost": ["EUR 1 692 000"], "Country": ["France", "United Kingdom", "Greece", "Cyprus", "Poland", "Belgium"], "Project_ACR": ["CE-IOT"], "Technology_Description": "The overall aim of CE-IoT is to develop an innovative framework of interplay between Circular Economy and IoT, to explore novel ways in which this interaction can drastically change the nature of products, services, business models and ecosystems. The CE-IoT framework will be bi-dimensional and bi-directional in terms of circularity, aiming to develop (i) novel circular economy business models and service supply chains to unlock CE-IoT synergies in order to generate direct value for customers/end-users and augmenting resource productivity across economies by forming new ecosystems that eliminate both negative externalities and the need for considerable resources altogether, and (ii) open, circular-by-design IoT architecture, where \u201csmart\u201d IoT objects (e.g., sensors, devices, systems and components) are integrated in the IoT ecosystem through patterns with proven key circularity-enabling properties (scalable connectivity, end-to-end security/privacy, dependability and interoperability) to maximize IoT resource and data harvesting in a new breed of circular-by-design IoT ecosystems.", "To": ["2022-06-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-07-01"], "Project_ID": ["777855"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER", "UNIVERSIDAD POMPEU FABRA", "UNIVERSITE DE BORDEAUX", "UNIVERSITE DE CAEN NORMANDIE", "ECOLE NATIONALE SUPERIEURE D'INGENIEURS DE CAEN", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "UNIVERSITA DEGLI STUDI DI GENOVA", "TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY", "INSTITUTO SUPERIOR TECNICO", "POLITECNICO DI MILANO", "THE UNIVERSITY OF NOTTINGHAM", "ECOLE POLYTECHNIQUE", "UNIVERSITEIT TWENTE", "UNIVERSITE LYON 1 CLAUDE BERNARD", "ASTRAZENECA UK LIMITED", "MEDIGUIDE LTD", "CAMELOT BIOMEDICAL SYSTEMS SRL", "THE MATHWORKS LIMITED", "CLK GMBH", "DATEXIM", "CLINICAL SCIENCE SYSTEMS", "THE REGENTS OF THE UNIVERSITY OF CALIFORNIA", "CARNEGIE MELLON UNIVERSITY"], "EU_Contribution": ["EUR 1 111 500"], "Project_Title": ["Nonlocal Methods for Arbitrary Data Sources"], "Total_Cost": ["EUR 1 111 500"], "Country": ["Germany", "Spain", "France", "France", "France", "United Kingdom", "Italy", "Israel", "Portugal", "Italy", "United Kingdom", "France", "Netherlands", "France", "United Kingdom", "Israel", "Italy", "United Kingdom", "Germany", "France", "Netherlands", "United States", "United States"], "Project_ACR": ["NoMADS"], "Technology_Description": "In NoMADS we focus on data processing and analysis techniques which can feature potentially very complex, nonlocal, relationships within the data. In this context, methodologies such as spectral clustering, graph partitioning, and convolutional neural networks have gained increasing attention in computer science and engineering within the last years, mainly from a combinatorial point of view. However, the use of nonlocal methods is often still restricted to academic pet projects. There is a large gap between the academic theories for nonlocal methods and their practical application to real-world problems. The reason these methods work so well in practice is far from fully understood.", "To": ["2022-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["777826"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["LATVIJAS UNIVERSITATE", "SUMY STATE UNIVERSITY", "THE UNIVERSITY OF SHEFFIELD", "UNIVERSITA DEGLI STUDI DI MODENA E REGGIO EMILIA", "OSTEOPLANT RESEARCH AND DEVELOPMENT SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA", "NANOPHARMA AS", "EESTI MATERJALITEHNOLOOGIATE ARENDUSKESKUSE AS"], "EU_Contribution": ["EUR 1 008 000"], "Project_Title": ["Nanostructural surface development for dental implant manufacturing"], "Total_Cost": ["EUR 1 008 000"], "Country": ["Latvia", "Ukraine", "United Kingdom", "Italy", "Poland", "Czech Republic", "Estonia"], "Project_ACR": ["NanoSurf"], "Technology_Description": "The project NanoSurf is targeted to strengthen international and intersectoral collaboration in dental implant research, sharing new ideas and knowledge transfer from research to market and vice versa. We will investigate nanostructured metal oxide coatings, 3D scaffolds, obtained by electrospinning deposition of organic nanofibers and lazer patterning of the implant surface using biotechnology, cell engineering and nanotechnology. Interdisciplinary project research and innovation goals are targeted to develop a new class of dental implants with advanced mechanical properties and improved surfaces, treated with nanotechnological methods which will demonstrate high biocompatibility, antibacterial properties and integration with a patient\u2019s bone. The developed devices will simplify dental surgery and avoid bacterial inflammatory complications after the implant surgery. This can provide better dental services and improve health of EU society. ", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Latvia"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-01-01"], "Project_ID": ["777926"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["THE UNIVERSITY OF EXETER", "THE UNIVERSITY OF EXETER"], "EU_Contribution": ["EUR 149 938"], "Project_Title": ["Forefront UAV Technology for Underpinning Rainforest Environmental Sustainability"], "Total_Cost": ["EUR 149 938"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["FUTURES"], "Technology_Description": "The proposed FUTURES project will use the novel UAV-Lidar technology conceived and developed in the current ERC-funded PAST project, in collaboration with the Brazilian National Institute for Space Research, in an entirely different socio-economic application aimed at helping Extractive Reserves (RESEXs) of the Brazilian Amazon. FUTURES proposes to utilise the UAV-Lidar system for creating 3D maps of forest structure and ground digital terrain models with unprecedented detail and interpret these data to improve the sustainable relationship between the RESEX forest residents and their environment, while maintaining and strengthening their economy and culture, and providing information to help them address emerging challenges. More specifically, FUTURES proposes to test the UAV-Lidar system for the following applications tailored to RESEXs: a) develop alternative options for sustainable extraction of non-timber forest products; b) design flood mitigation strategies, such as route planning for easier access to healthcare and emergency services, schools and local consumer markets during the rainy season; c) identify new, sustainable, under-forest fisheries; and d) increase the awareness of archaeological heritage in RESEXs with implications to develop cultural heritage tourism. Addressing the above challenges are also important for RESEXs and the Brazilian government in materialising their REDD+ (Reducing Emissions from Deforestation and forest Degradation) initiative, and for the European Union to ensure its success and leadership in implementing its forest conservation, sustainability and carbon mitigation goal of reducing tropical deforestation to at least 50% by 2020.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["777845"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN", "HUNTINGTON'S DISEASE ASSOCIATION OF IRELAND", "THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN", "UNIVERSITAET ULM", "THE UNIVERSITY OF READING", "COMTRADE PROGRAMSKE RESITVE DOO", "ICON CLINICAL RESEARCH LIMITED", "ICON CLINICAL RESEARCH"], "EU_Contribution": ["EUR 828 000"], "Project_Title": ["Patient Centered Connected Health Model of Care for Huntingtons Disease"], "Total_Cost": ["EUR 828 000"], "Country": ["Ireland", "Ireland", "United Kingdom", "Germany", "United Kingdom", "Slovenia", "Ireland", "France"], "Project_ACR": ["CareHD"], "Technology_Description": "HD is a monogentic disease, meaning modification in a single gene occurring in all cells of the body. In Western countries it is estimated that 5-7 people per 100,000 are affected by HD. Currently there is no cure for the disease and effective management is key to quality of life for those who are affected. Patients and families who are living with the disease face multiple social and self-management issues. For example, stigma of the disease alongside social isolation have been key drivers in terms of high levels of mental health difficulties. CH has the ability to assist with many of the difficulties faced by HD, RD and indeed other symptom related diseases. For example, CH can monitor and identify key intervention points along the disease progression pathway, it can inform and facilitate integrated care, it can assist with joining key stakeholders together in a shared ecosystem, and importantly it can assist patients and their families in terms of reducing isolation, optimising self-management and thus increasing empowerment and self-actualisation. Further, CH has the ability to optimise scarce resources in an over stretched health care system and thus produce effective and efficient outcomes.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Other", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-01-01"], "Project_ID": ["777991"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["UNIVERSIDAD DE GRANADA", "ASOCIACION ARTE TECNOLOGIA Y SOCIEDAD ARTES", "ENGINLIFE-ENGINEERING SOLUTIONS", "UNIVERSITA DEGLI STUDI DI ENNA KORE", "ZEPHYRO SPA", "ASSOCIAZIONE MICROCOSMI ONLUS", "CTADVENTURE SP ZOO", "ATHINA-EREVNITIKO KENTRO KAINOTOMIAS STIS TECHNOLOGIES TIS PLIROFOFORIAS, TON EPIKOLNONION KAI TIS GNOSIS"], "EU_Contribution": ["EUR 1 296 000"], "Project_Title": ["loW Altitude Remote sensing for the Monitoring of the state of Cultural hEritage Sites: building aninTegrated model for maintenance."], "Total_Cost": ["EUR 1 296 000"], "Country": ["Spain", "Spain", "Italy", "Italy", "Italy", "Italy", "Poland", "Greece"], "Project_ACR": ["Warmest"], "Technology_Description": "WARMEST strategic goal is to create a novel comprehensive Decision Support System that will carry out a Cultural Heritage Risk Analsys (CHRA) and suggest improvements in maintenance and disaster management procedures for cultural and natural heritage sites. The maintenance and disaster management plans developed with the support of the Decision Support System, will consider current and future scenarios, setting priorities for the actions to be taken, both on economic and art historical grounds, delivering required information where and when needed, in a user-friendly way. To this end the consortium will develop new technologies to collect data on the conservation status of the sites and new tools to analyse it, as there is presently a lack of data that is specifically relevant to understanding climate change impacts; these technologies in case of emergence, can help to assess the impact of events quickly and on large areas. WARMEST is challenging from a management and from an engineering point of view, given that regulations are strict (to preserve the natural, archaeological and historical values), the factors to take into consideration are complex and not homogenous (technical, economic, historical), the information to deliver differentiated according to users and concise or detailed when needed. The goals set by WARMEST can be met only by creating an heterogeneus consortium, involving knowledgeable experts from various fields from private and public institutions. 9 beneficiaries will participate to the WARMEST consortium; 3 academic institutions, 2 association involved in heritage management and 4 private companies. 4 end users will be commited to the project as external partners to obtain the right mixing of knowledge.", "To": ["2021-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations"], "From": ["2017-12-01"], "Project_ID": ["777981"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["LATVIJAS UNIVERSITATE", "KAUNO TECHNOLOGIJOS UNIVERSITETAS", "LULEA TEKNISKA UNIVERSITET", "USTAV POLYMEROV - SLOVENSKA AKADEMIA VIED", "DANMARKS TEKNISKE UNIVERSITET", "BALTIC SCIENTIFIC INSTRUMENTS SIA", "MATERIALS RESEARCH CENTER", "SYNPO AKCIOVA SPOLECNOST", "UAB SPORTINE AVIACIJA IR KO", "BELARUSIAN STATE UNIVERSITY", "DREXEL UNIVERSITY"], "EU_Contribution": ["EUR 1 246 500"], "Project_Title": ["MULTIFUNCTIONAL POLYMER COMPOSITES DOPED WITH NOVEL 2D NANOPARTICLES FOR ADVANCED APPLICATIONS"], "Total_Cost": ["EUR 1 246 500"], "Country": ["Latvia", "Lithuania", "Sweden", "Slovakia", "Denmark", "Latvia", "Ukraine", "Czech Republic", "Lithuania", "Belarus", "United States"], "Project_ACR": ["NANO2DAY"], "Technology_Description": "NANO2DAY is aiming at the development of advanced multifunctional composites with outstanding electronic and mechanical properties by incorporation of novel MXene nanosheets into polymer matrixes. The project will firstly go forward to the rational design and systematic exploration of MXene-polymer nanocomposites for wearable electronics and advanced structural components for airspace applications. This will be achieved by i) intersectoral consolidation and sharing of knowledge and expertise of 11 members from Europe and USA working in different areas and ii) collaborative research on the development and assessment of novel materials, including technology, characterisation, modelling, and validation. The concept explored in the project accounts for finding and extending the application potential of MXene-doped polymers and validation of their effectiveness compared to well-known graphene-doped polymers. The innovative aspects followed in the project are based on up-scaling of novel technologies for \u201cclose-to-industrial\u201d synthesis of MXenes and MXene-doped polymer masterbatches and implementation of MXenes into design of structural polymer composites, including FRPs. NANO2DAY will essentially contribute to the integration of scientific insights into innovation-based industrial environment and successful implementation of novel advanced materials into practical applications.", "To": ["2022-04-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Latvia"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-05-01"], "Project_ID": ["777810"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI CATANIA", "MARTIN-LUTHER-UNIVERSITAET HALLE-WITTENBERG", "LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE", "Faculdade de letras da Universidade de Lisboa", "UNIVERSIDAD DE BUENOS AIRES", "CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TECNICAS (CONICET)", "UNIVERSIDADE FEDERAL DE SANTA CATARINA.", "UNIVERSIDADE FEDERAL DE MINAS GERAIS"], "EU_Contribution": ["EUR 544 500"], "Project_Title": ["Kant in South America"], "Total_Cost": ["EUR 738 000"], "Country": ["Italy", "Germany", "United Kingdom", "Portugal", "Argentina", "Argentina", "Brazil", "Brazil"], "Project_ACR": ["KANTINSA"], "Technology_Description": "A consortium of 4 EU Universities and 4 Southern American (SA) academic institutions analyze critically the development of Kant scholarship in Southern America in the last 15 years, following the booming of Kant studies in that continent over that period and the exponential increase of its quality. Top SA Kant scholars are enrolled in the project that promises to enlarge greatly the competence of EU colleagues and in turn profit from their feedback. Early stage researchers from both ends also take part to the exchange. The consortium builds on a web of established relations of most of the participants, at the personal and institutional level.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["777786"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA", "TEAGASC - AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY", "CONSIGLIO NAZIONALE DELLE RICERCHE", "UNIVERSITA TA MALTA", "PROBIOTICAL SPA", "ADVANCE SCIENCE (FORBAIRT EOLAIOCHTA TEO) LIMITED", "NUTRI BIOTECH SERVICES LTD", "CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TECNICAS (CONICET)"], "EU_Contribution": ["EUR 346 500"], "Project_Title": ["Nourishing PRObiotics to Bees to Mitigate Stressors"], "Total_Cost": ["EUR 346 500"], "Country": ["Italy", "Ireland", "Italy", "Malta", "Italy", "Ireland", "Malta", "Argentina"], "Project_ACR": ["NO PROBleMS"], "Technology_Description": "In the last decades, bees have been threatened by a number of biotic and abiotic stresses, which strongly affect beehives integrity. Consequently, the beekeeping sector together with ecosystem and agricultural sectors depending on pollinators suffer of missed pollination. Nosema ceranae is a bee gut parasite that has received particular attention in the last years because it causes bee colonies to collapse due to energy and nutrient deficiency. Furthermore, the bee gut microbiota undergoes a dysbiosis process following infection. N. ceranae virulence in infected bees escalates when forager bees uptake sub-lethal doses of insecticides such as Neonicotinoids from the polluted agricultural environment surrounding the hive. The European Union banning of antibiotics for therapeutic use in the beekeeping sector approved in 2001 has deprived beekeepers of Fumagillin-B, the sole antibiotic previously available to control Nosema sp.. The need to find alternative treatments to fight bee diseases has led researchers to the study of ecofriendly practices. Our proposed research aims to develop a strategy for the health of the bee gut based on microbial and plant resources to inhibit N. ceranae proliferation and to mitigate the effect of synergic bee stressors. The project will be developed by a consortium formed by 4 research institutions and 3 SMEs of 3 different European countries and a third country (Argentina). Research institutions will do the experimental work on bees aimed at the definition of a strategy based on the use of beneficial bacteria and plant extracts and at the evaluation of the impact on the bee gut of the developed formulation. SMEs will contribute to the choice of the ingredients of the prototype formulation and at finding a strategy to produce it. ESR and ER will perform secondments in research institutions and SMEs to facilitate transfer of knowledge between the research and production sector.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["777760"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA", "UNIVERSITE GRENOBLE ALPES", "AGGELIDIS I.-PALLIKARIDIS X. OE", "TEATAR TSVETE", "INSTITUT PO ROBOTIKA", "TECHNOLOGIKO EKPEDEFTIKO IDRIMA ANATOLIKIS MAKEDONIAS & THRAKIS", "CENTRE HOSPITALIER UNIVERSITAIRE DE GRENOBLE", "CENTRO DE VISION POR COMPUTADOR", "KOKURITSU DAIGAKU HOJIN KYUSHU KOGYO DAIGAKU", "UNIVERSIDAD DE CHILE", "UNIVERSITE HASSAN II DE CASABLANCA"], "EU_Contribution": ["EUR 1 296 000"], "Project_Title": ["Cyber-Physical Systems for PEdagogical Rehabilitation in Special EDucation"], "Total_Cost": ["EUR 1 386 000"], "Country": ["Spain", "France", "Greece", "Bulgaria", "Bulgaria", "Greece", "France", "Spain", "Japan", "Chile", "Morocco"], "Project_ACR": ["CybSPEED"], "Technology_Description": "The aim of the current MSCA RISE project CybSPEED is to advance a novel framework for analysis, modelling, synthesis and implementation of Cyber-Physical Systems for pedagogical rehabilitation in special education, based on a combination of the best of experience and achievements of the partners in the domains of brain-aware robotics, cognitive biometrics, computational intelligence and reasoning in humanoid and non-humanoid robots for education. CybSPEED project builds on the results and insights of the recently completed project funded by EEA Grant of Bulgaria and Norway \"METEMSS: Methodologies and technologies for enhancing the motor and social skills of children with developmental problems\" (IR-BAS), on a logical projection of the EU funded project \"Social & Smart\", called \u201cStorytelling NAO\u201d of Spain (UPV/EHU) and on the ongoing research of the project \u201cSpecial Education Robot Teaching Assistant (EduBot)\u201d of Greece (EMaTTech) funded by the Stavros Niarchos Foudation. CybSPEED project emphasizes the intrinsic-motivational approach to learning by designing human-robot situations (games, pedagogical cases, artistic performances) and advanced interfaces (brain-computer, eye-gaze tracking and virtual reality) where children and students interact with the novel technology to enhance the underlying self-compensation and complementarity of brain encoding during learning. The CybSPEED project aspires to establish as well as to sustain an innovation network across the EU, Japan in the Far East, Chile in South America and Morocco in West Africa that will pursue top-level research on three levels \u2013 1) analysis of cognitive biometrics signals, 2) modeling of the learner-robot interaction and 3) development of novel instruments toward an optimal design of Cyber-Physical Systems for improved pedagogical rehabilitation in education.", "To": ["2021-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Research Organisations", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["777720"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["UNIVERSIDADE DE AVEIRO", "UNIVERSITAT DE VALENCIA", "THE UNIVERSITY OF SHEFFIELD", "UNIVERSIDAD NACIONAL AUTONOMA DE MEXICO", "Universidade Federal do Par\u00e1"], "EU_Contribution": ["EUR 220 500"], "Project_Title": ["Fundamental fields and compact objects: theory and astrophysical phenomenology"], "Total_Cost": ["EUR 220 500"], "Country": ["Portugal", "Spain", "United Kingdom", "Mexico", "Brazil"], "Project_ACR": ["FunFiCO"], "Technology_Description": "Epoch-making observational, theoretical and computational developments make this an exceptional time for the understanding of gravity in the strong field regime. The recent detection of gravitational waves (GWs), together with other ongoing experiments; the discovery of unexpected compact objects in General Relativity (GR); and the breakthroughs in the field of Numerical Relativity (NR), make strong gravity a central player in the scientific scene. Exploring different scenarios in this context is timely and synergies are mandatory, for such an endeavor.", "To": ["2021-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Portugal"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["777740"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE", "ASYMPTOTE LIMITED", "UNIVERSIDADE DE COIMBRA", "FUNDACIO INSTITUT DE CIENCIES FOTONIQUES", "Universidade da Madeira", "BIOSEARCH S.A.", "INSTITUT DES SCIENCES ET INDUSTRIES DU VIVANT ET DE L'ENVIRONNEMENT - AGRO PARIS TECH", "CLOCK-T", "CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TECNICAS (CONICET)"], "EU_Contribution": ["EUR 634 500"], "Project_Title": ["Preservation of microorganisms by understanding the protective mechanisms of oligosaccharides"], "Total_Cost": ["EUR 634 500"], "Country": ["France", "United Kingdom", "Portugal", "Spain", "Portugal", "Spain", "France", "France", "Argentina"], "Project_ACR": ["PREMIUM"], "Technology_Description": "Microorganisms offer a large variety of functionalities that remains under-exploited due to the current inability to perform long term preservation at an industrial scale. PREMIUM project is a four-year multidisciplinary project involving a consortium of 5 academic partners from 5 European countries (France, Spain and Portugal) and 1 from third country (Argentina) and 3 industrial partners (France, United Kingdom and Spain). The project aims at developing new strategies to preserve lactic acid bacteria from laboratory to industrial scale. The innovative approaches of the project lay on: i) producing oligosaccharides of original composition for protecting cells; ii) developing novel preservation process based on encapsulation and evaluating the environmental impact of the whole system of production and stabilization of micro-organisms from the laboratory step iii) developing high-throughput characterization and screening tools such as vibrational spectroscopy. A multicriteria analysis approach will be developed to identify the most promising strategies for industrial eco-friendly preservation of micro-organisms. ", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["777657"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["EUROPEAN FUTURE INNOVATION SYSTEM CENTRE", "CSIL - CENTRO STUDI INDUSTRIA LEGGERA SOCIETA' COOPERATIVA", "FONDATION EUROPEENNE DE LA SCIENCE", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.", "EUROPEAN MOLECULAR BIOLOGY LABORATORY", "EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH", "CONSORCIO PARA LA CONSTRUCCION EQUIPAMIENTO Y EXPLOTACION DEL LABORATORIO DE LUZ SINCROTRON", "STIFTUNG DEUTSCHES ELEKTRONEN-SYNCHROTRON DESY"], "EU_Contribution": ["EUR 1 498 717,50"], "Project_Title": ["Charting Impact Pathways of Investment in Research Infrastructures"], "Total_Cost": ["EUR 1 498 717,50"], "Country": ["Belgium", "Italy", "France", "Germany", "Germany", "Switzerland", "Spain", "Germany"], "Project_ACR": ["RI Impact Pathways"], "Technology_Description": "The aim of the project is to develop a model describing the socio-economic impact of research infrastructures and of their related financial investments. The model will be developed in a modular manner adapting it to a broad range of scientific domains and types of infrastructures. The project outcomes are expected to contribute to a common approach at international level and facilitate investments in research infrastructures by funding agencies and other stakeholders. The project activities will take into account the work of the Research Infrastructure Socio-Economic Impact Working group, being established by the OECD Global Science Forum, and involve major key international players in this domain. More specifically RI Impact Pathways project plans to carry out a comprehensive stocktaking exercise on the existing approaches for impact assessment of research infrastructures and map the current and future data gathering needs of the key stakeholder groups. The goal is to identify the strengths and limitations of the existing approaches, detect existing gaps and overlaps, as well as to assess the level of complexity of the developed conceptual advances. Further a set of activities will be devoted to map the needs of various stakeholders associated with IA of RIs. Employing participatory and systems thinking approaches the project will develop a modular impact assessment model that represents all major impact pathways of distinct types of research infrastructures. The IA model will be put to practice by defining a set of reference indicators, providing guidance on the most appropriate monitoring and evaluation approaches and testing its feasibility with pilot research infrastructures. The outcomes of the validated model will be integrated with the ESF MERIL platform that is authoritative and exhaustive online source of scientific and policy relevant data on research infrastructures in Europe.", "To": ["2020-06-30, ongoing project"], "Meta": [""], "Topic_s": ["INFRASUPP-02-2017 - Policy and international cooperation measures for research infrastructures"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Belgium"], "Activity": ["Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["777563"], "Call_for_Proposal": ["H2020-INFRASUPP-2017-1"]}, -{"Partners": ["PERCUROS BV", "ACADEMISCH ZIEKENHUIS LEIDEN", "ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM", "TECHNISCHE UNIVERSITEIT DELFT", "UNIVERSITA DEGLI STUDI DI CAMERINO", "TECOBIOSCIENCES GMBH", "UNIVERSITEIT VAN AMSTERDAM", "THE UNIVERSITY OF SHEFFIELD", "UNIVERSITEIT MAASTRICHT", "JENACELL GMBH", "MEDRES-MEDICAL RESEARCH GMBH", "AUGEAS ASSOCIAZIONE DI SPORT PROMOZIONE E TURISMO", "PROGREDUM GMBH", "ASSOCIAZIONE CULTURALE CASTELLI ROMANI GREEN TOUR", "BOSCHIVA MELCHIORRI SRL", "HELRIK AND LOUW COMPANY LTD", "UNIWERSYTET JAGIELLONSKI"], "EU_Contribution": ["EUR 2 430 000"], "Project_Title": ["Personalised Postoperative Immunotherapy To Improving Cancer Outcome and improving quality of life"], "Total_Cost": ["EUR 2 430 000"], "Country": ["Netherlands", "Netherlands", "Netherlands", "Netherlands", "Italy", "Germany", "Netherlands", "United Kingdom", "Netherlands", "Germany", "Germany", "Italy", "Germany", "Italy", "Italy", "United Kingdom", "Poland"], "Project_ACR": ["CANCER"], "Technology_Description": "During this RISE project we aim to develop nanoparticle-based encapsulated libraries of different immunotherapeutic biomolecules for treatment after surgery as part of a novel cancer management strategy. The current state-of-art for the management of cancer starts with surgery, after identification of an accessible tumour mass. Surgery remains an effective treatment option for many types of cancer today and it is considered curative treatment for most solid tumours. It forms part of a multidisciplinary approach used in conjunction with radiotherapy or chemotherapy. These approaches, however, have several limitations, including inability of surgical resection to affect distal metastatic disease, toxicity to healthy tissues with chemotherapy and lack of effectiveness of radiation therapy in more aggressive tumours. The observation that cancer can relapse months or years after initial surgery implies that micrometastases still resides within the body in a latent state. Our proposal is to take cancer therapy to beyond state-of-art by implementing techniques which will take us into new directions.", "To": ["2022-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Netherlands"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["777682"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["INSTITIUID TEICNEOLAIOCHTA BHAILE ATHA CLIATH", "INSTITUT DE RECHERCHE ET D'INNOVATION", "UNIVERSITY OF DURHAM", "DUBLIN CITY COUNCIL", "COMMUNAUTE D'AGGLOMERATION PLAINE COMMUNE", "UNIVERSIDAD DE LAS ARTES"], "EU_Contribution": ["EUR 463 500"], "Project_Title": ["Real Smart City"], "Total_Cost": ["EUR 463 500"], "Country": ["Ireland", "France", "United Kingdom", "Ireland", "France", "Ecuador"], "Project_ACR": ["ReaLsMs"], "Technology_Description": "The overarching objective of the ReaLsMs is to develop and implement a perspective on the Smart City through critical humanities research and innovation in the context of the Digital Studies. The joint research fields of ReaLsMs will be the development of historical and philosophical underpinnings of the Data City and the implementation of the Smart City within local governance structures, including Dublin City Council and Plaine Commune (Paris North). Consisting of a network of three academic partners in the EU, Dublin Institute of Technology - School of Creative Arts, Computer Science and Architecture, (DIT, IE), the Institut de Recherche et d\u2019Innovation (IRI) at the Centre Pompidou (FR) and Durham University, the Centre for Humanities Innovation (DU, UK). The 2 non-academic partners located in the EU are Dublin City Council (DCC, IE) and Plaine Commune (FR). The Third Country academic partners is the Universidad de las Artes in Ecuador (UA, Ecuador). The purpose of developing this consortium as a Marie Sklodowska-Curie Research and Innovation Staff Exchange is to share knowledge across disciplines in order to develop transdisciplinary model for \u201creal smart city,\u201d which is defined as a Smart City that is based on a critical humanities perspective, where citizens are the proper data brokers, engaging through public fora for debate and new technologies that enable citizen participation. Through a international and cross-sectoral network, the aim is to across sectors, allowing academic researchers to work with civic government and data collection while non-academic partners can benefit from the insights of academic partners to create new forms of education that illuminate the \u201cblack box\u201d of Smart City technology. The expected outcome of research are a new transdisciplinary epsiteme of the Smart and Data City that is rooted in Digital Studies and subsequently informed methods for handling data collected through Smart City infrastructure.", "To": ["2020-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["777707"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON", "GEORG-AUGUST-UNIVERSITAT GOTTINGENSTIFTUNG OFFENTLICHEN RECHTS", "CONSIGLIO NAZIONALE DELLE RICERCHE", "UNIWERSYTET WARSZAWSKI", "EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH", "ATHINA-EREVNITIKO KENTRO KAINOTOMIAS STIS TECHNOLOGIES TIS PLIROFOFORIAS, TON EPIKOLNONION KAI TIS GNOSIS", "UNIVERSITAET BIELEFELD", "UNIVERSIDADE DO MINHO", "STICHTING EIFL.NET", "UNIVERSITEIT GENT", "UNIVERSITETET I OSLO", "COAR E.V.", "COOPERACION LATINOAMERICANA DE REDES AVANZADAS", "KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW", "THE UNIVERSITY OF EDINBURGH", "UNIVERSITY OF GLASGOW", "ELLINOGERMANIKI AGOGI SCHOLI PANAGEA SAVVA AE", "RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN", "ETHNIKO IDRYMA EREVNON", "OPEN LIBRARY OF HUMANITIES", "DIGITAL RESEARCH INFRASTRUCTURE FOR THE ARTS AND HUMANITIES", "UNIVERSITAT WIEN", "INSTITUTE OF MATHEMATICS AND INFORMATICS AT THE BULGARIAN ACADEMY OF SCIENCE", "RUDER BOSKOVIC INSTITUTE", "UNIVERSITY OF CYPRUS", "SYDDANSK UNIVERSITET", "TARTU ULIKOOL", "HELSINGIN YLIOPISTO", "CONSORTIUM UNIVERSITAIRE DE PUBLICATIONS NUMERIQUES COUPERIN", "UNIVERSITAT KONSTANZ", "DEBRECENI EGYETEM", "LANDSPITALI UNIVERSITY HOSPITAL", "THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN", "BAR ILAN UNIVERSITY", "LATVIJAS UNIVERSITATE", "KAUNO TECHNOLOGIJOS UNIVERSITETAS", "UNIVERSITE DU LUXEMBOURG", "UNIVERSITA TA MALTA", "TECHNISCHE UNIVERSITEIT DELFT", "Unitatea Executiva pentru Finantarea Invatamantului Superior, a Cercetarii, Dezvoltarii si Inovarii", "UNIVERZITET U BEOGRADU", "CENTRUM VEDECKO TECHNICKYCH INFORMACII SLOVENSKEJ REPUBLIKY", "UNIVERZA V LJUBLJANI", "FUNDACION ESPANOLA PARA LA CIENCIA Y LA TECNOLOGIA", "KUNGLIGA BIBLIOTEKET", "UNIVERSITAT ZURICH", "IZMIR INSTITUTE OF TECHNOLOGY", "JISC LBG"], "EU_Contribution": ["EUR 9 999 997,50"], "Project_Title": ["OpenAIRE Advancing Open Scholarship"], "Total_Cost": ["EUR 9 999 997,50"], "Country": ["Greece", "Germany", "Italy", "Poland", "Switzerland", "Greece", "Germany", "Portugal", "Netherlands", "Belgium", "Norway", "Germany", "Uruguay", "Netherlands", "United Kingdom", "United Kingdom", "Greece", "Germany", "Greece", "United Kingdom", "France", "Austria", "Bulgaria", "Croatia", "Cyprus", "Denmark", "Estonia", "Finland", "France", "Germany", "Hungary", "Iceland", "Ireland", "Israel", "Latvia", "Lithuania", "Luxembourg", "Malta", "Netherlands", "Romania", "Serbia", "Slovakia", "Slovenia", "Spain", "Sweden", "Switzerland", "Turkey", "United Kingdom"], "Project_ACR": ["OpenAIRE-Advance"], "Technology_Description": "OpenAIRE-Advance continues the mission of OpenAIRE to support the Open Access/Open Data mandatesinEurope. By sustaining the current successful infrastructure, comprised of a human network and robust technical services, it consolidates its achievements while working to shift the momentum among its communities to Open Science, aiming to be a trusted e-Infrastructurewithin the realms of the European Open Science Cloud.In this next phase, OpenAIRE-Advance strives to empower its National Open Access Desks (NOADs) so they become a pivotal part within their own national data infrastructures, positioningOA and open science onto national agendas. The capacity building activities bring together experts ontopical task groups in thematic areas(open policies, RDM, legal issues, TDM), promoting a train the trainer approach, strengthening and expanding the pan-European Helpdesk with support and training toolkits, training resources and workshops.It examines key elements of scholarly communication, i.e., co-operative OA publishing and next generation repositories, to develop essential building blocks of the scholarly commons.On the technical level OpenAIRE-Advance focuses on the operation and maintenance of the OpenAIRE technical TRL8/9 services,and radically improvesthe OpenAIRE services on offer by: a) optimizing their performance and scalability, b) refining their functionality based on end-user feedback, c) repackagingthem into products, taking a professional marketing approach with well-defined KPIs, d)consolidating the range of services/products into a common e-Infra catalogue to enable a wider uptake.OpenAIRE-Advancesteps up its outreach activities with concrete pilots with three major RIs,citizen science initiatives, and innovators via a rigorous Open Innovation programme. Finally, viaits partnership with COAR, OpenAIRE-Advance consolidatesOpenAIRE\u2019s global roleextending its collaborations with Latin America, US, Japan, Canada, and Africa.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["EINFRA-12-2017 - Data and Distributed Computing e-infrastructures for Open Science"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Greece"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other", "Other", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Other", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other"], "From": ["2018-01-01"], "Project_ID": ["777541"], "Call_for_Proposal": ["H2020-EINFRA-2017"]}, -{"Partners": ["UNIVERSITAET STUTTGART", "SWEDISH SPACE CORPORATION", "EBERHARD KARLS UNIVERSITAET TUEBINGEN", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 3 009 563,61"], "Project_Title": ["European Stratospheric Balloon Observatory Design Study"], "Total_Cost": ["EUR 3 267 158,11"], "Country": ["Germany", "Sweden", "Germany", "Germany", "Spain"], "Project_ACR": ["ESBO DS"], "Technology_Description": "Following the findings of the H2020-funded ORISON project, we propose the design and development of a new European astronomical research infrastructure for stratospheric balloon-based telescopes. Our approach is to provide a versatile community-accessible observatory capable of covering unserved scientific needs, including those of star- and planet formation studies and exoplanet research. These are particularly associated with requirements for high spatial and spectral resolution far-infrared (FIR) observations, high sensitivity UV observations, and highly accurate visible light photometry. To a certain extent, these needs could also be addressed by space missions. A balloon infrastructure, however, will offer a more cost-efficient and flexible approach, allowing instruments more adaptable to evolving needs (exchangeable and less risk-adverse), longer overall observation times (possibility to refill cooling fluids), and larger mirror sizes (less severe launcher restrictions). So far, stratospheric telescopes, with the exception of SOFIA, have mostly served a single purpose and did not fly more than a few times. The proposed infrastructure, in contrast, will provide regular flights, allowing it to operate as a true observatory.", "To": ["2021-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["INFRADEV-01-2017 - Design Studies"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations"], "From": ["2018-03-01"], "Project_ID": ["777516"], "Call_for_Proposal": ["H2020-INFRADEV-2017-1"]}, -{"Partners": ["SCIENCE AND TECHNOLOGY FACILITIES COUNCIL", "THE BRITISH LIBRARY BOARD", "MONASH UNIVERSITY", "EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH", "DATACITE \u2013 INTERNATIONAL DATA CITATION INITIATIVE", "EUROPEAN MOLECULAR BIOLOGY LABORATORY", "UNIVERSITAET BREMEN", "PUBLIC LIBRARY OF SCIENCE", "PUBLISHERS INTERNATIONAL LINKING ASSOCIATION INC NON PROFIT CORPORATION", "ORCID INC.", "KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW", "HINDAWI LIMITED"], "EU_Contribution": ["EUR 4 998 650"], "Project_Title": ["Connected Open Identifiers for Discovery, Access and Use of Research Resources"], "Total_Cost": ["EUR 5 246 117,50"], "Country": ["United Kingdom", "United Kingdom", "Australia", "Switzerland", "Germany", "Germany", "Germany", "United States", "United States", "United States", "Netherlands", "United Kingdom"], "Project_ACR": ["FREYA"], "Technology_Description": "The goal of the FREYA consortium is to iteratively extend a robust environment for Persistent Identifiers (PIDs) into a core component of European and global research e-infrastructures. The resulting FREYA services will cover a wide range of resources in the research and innovation landscape and enhance the links between them so that they can be exploited in many disciplines and research processes. This will provide an essential building block of the European Open Science Cloud (EOSC). Moreover, the FREYA project will establish an open, sustainable, and trusted framework for collaborative self-governance of PIDs and services built on them.", "To": ["2020-11-30, ongoing project"], "Meta": [""], "Topic_s": ["EINFRA-21-2017 - Platform-driven e-infrastructure innovation"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Other", "Other", "Other", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-12-01"], "Project_ID": ["777523"], "Call_for_Proposal": ["H2020-EINFRA-2017"]}, -{"Partners": ["UNIVERSITE D'ORLEANS", "BODYCAP", "STAFFORDSHIRE UNIVERSITY", "PODO ACTIVA SL", "Pontificia Universidad Catolica del Peru", "PONTIFICIA UNIVERSIDAD JAVERIANA", "UNIVERSITE IBNOU ZOHR A AGADIR", "Hospital Nacional Dos de Mayo"], "EU_Contribution": ["EUR 504 000"], "Project_Title": ["Smartphone Thermal ANalysis for Diabetic foot Ulcer Prevention and treatment"], "Total_Cost": ["EUR 504 000"], "Country": ["France", "France", "United Kingdom", "Spain", "Peru", "Colombia", "Morocco", "Peru"], "Project_ACR": ["STANDUP"], "Technology_Description": "Diabetic foot (DF) disease includes neuropathy, peripheral arterial disease and infection which may lead to ulceration and subsequent lower limb amputation. DF ulcers could be further reduced according to diabetes experts. Temperature is one of the possible clinical parameter which is not currently well exploited. Recently, smartphones can acquire thermal images thanks to dedicated thermal camera. The STANDUP project proposes a smartphone based system such that mobile, accurate, friendly, low cost and fast thermal analysis of the plantar foot surface can be achieved. The smartphone thermal imaging system will be composed of a smartphone and of a FlirOne thermal camera. In the STANDUP project, two smartphone applications will be developed. The first one (A1: hyperthermia detection and analysis of thermal variations in time) will permit to detect possible hyperthermia of the plantar foot surface and will analyze temperature variations on targeted regions of interest. The second smartphone application will assess temperature, color, and 3D shape of DF ulcer along time. These smartphone applications will be evaluated during clinical trials in hospitals. In the first clinical trial, a cold stress test will permit to detect neuropathy and peripheral arterial disease. In the second clinical trial, temperature, color, and 3D shape in DF ulcers will be studied during its treatment. The third clinical study will assess the effectiveness of new insoles, these new insole will be developed during STANDUP with the objective to relive hyperthermia in DF. These 2 smartphone applications will be enhanced to result in an advanced prototype of smartphone based system for the targeted medical applications. This advanced smartphone thermal prototype, and the new insoles, will be developed during STANDUP to rapidly address novel market demands in DF early diagnosis, and in DF ulcer prevention and treatment and will lead to economic benefits for social and healthcare system.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-01-01"], "Project_ID": ["777661"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["UNIVERSIDAD DE MALAGA", "DEKRA TESTING AND CERTIFICATION SAU", "Teknologian tutkimuskeskus VTT Oy", "PIETRZYK SLAWOMIR", "TIME.LEX", "NORDUNET A/S"], "EU_Contribution": ["EUR 2 047 937,50"], "Project_Title": ["Design of the European mobile network operator for research"], "Total_Cost": ["EUR 2 047 937,50"], "Country": ["Spain", "Spain", "Finland", "Poland", "Belgium", "Denmark"], "Project_ACR": ["EuWireless"], "Technology_Description": "The objective of EuWireless proposal is to develop the design of the first pan-European infrastructure to support research in mobile communication networks using regulated spectrum, with the goal of contributing to keep Europe\u2019s leadership in mobile communication technologies. The output of the project will be a complete design report addressing the pan-European operator, the regulatory aspects, the business model, the technical solutions and the roadmap for implementation of the proposed infrastructure, as well as prototypes that confirm its feasibility.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["INFRADEV-01-2017 - Design Studies"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other"], "From": ["2018-01-01"], "Project_ID": ["777517"], "Call_for_Proposal": ["H2020-INFRADEV-2017-1"]}, -{"Partners": ["TRUST-IT SERVICES LIMITED", "GEORG-AUGUST-UNIVERSITAT GOTTINGENSTIFTUNG OFFENTLICHEN RECHTS", "ROYAL IRISH ACADEMY", "RESEARCH DATA ALLIANCE FOUNDATION", "THE UNIVERSITY OF EDINBURGH"], "EU_Contribution": ["EUR 3 500 000"], "Project_Title": ["The European plug-in to the global Research Data Alliance"], "Total_Cost": ["EUR 3 500 000,50"], "Country": ["United Kingdom", "Germany", "Ireland", "United Kingdom", "United Kingdom"], "Project_ACR": ["RDA Europe 4.0"], "Technology_Description": "RDA Europe 4.0 addresses the INFRASUPP-02-2017 call targeting the area \u201cEuropean support to the Research Data Alliance, RDA\u201d designing Europe\u2019s contribution to implementation of an effective governance model and strategy in RDA global, while ensuring that RDA delivers on locally relevant issues. RDA Europe 4.0 focuses on the need for open and interoperable sharing of research data & on the need to build social, technical and cross-disciplinary links to enable such sharing on a global scale. It strives to do this with its community-driven and bottom-up approach launched since 2012. In fact, RDA Europe 4.0 directly builds on the current RDA Europe effort, by efficiently bringing in the organisations that implemented RDA Europe since 2012.", "To": ["2020-05-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["INFRASUPP-02-2017 - Policy and international cooperation measures for research infrastructures"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["United Kingdom"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["777388"], "Call_for_Proposal": ["H2020-INFRASUPP-2017-1"]}, -{"Partners": ["THE MANCHESTER METROPOLITAN UNIVERSITY", "INSTITUT DRUSTVENIH ZNANOSTI IVO PILAR", "TALLINN UNIVERSITY", "UNIVERSITAET BREMEN", "AGENCIA CATALANA DE LA JUVENTUD", "PANTEIO PANEPISTIMIO KOINONIKON KAIPOLITIKON EPISTIMON", "DEBRECENI EGYETEM", "UNIVERSITY OF ESSEX", "UNIVERZITA SV CYRILA A METODA V TRNAVE", "DAUGAVPILS UNIVERSITATE", "INSTITUTO UNIVERSITARIO DE LISBOA", "JYVASKYLAN YLIOPISTO", "ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA", "UNIVERSITY COLLEGE LONDON", "KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW", "EUROPEAN SOCIAL SURVEY EUROPEAN RESEARCH INFRASTRUCTURE CONSORTIUM"], "EU_Contribution": ["EUR 2 048 880"], "Project_Title": ["European Cohort Development Project"], "Total_Cost": ["EUR 2 048 880"], "Country": ["United Kingdom", "Croatia", "Estonia", "Germany", "Spain", "Greece", "Hungary", "United Kingdom", "Slovakia", "Latvia", "Portugal", "Finland", "Italy", "United Kingdom", "Netherlands", "United Kingdom"], "Project_ACR": ["ECDP"], "Technology_Description": "The European Cohort Development Project (ECDP) is a Design Study which will create the specification and business case for a European Research Infrastructure that will provide, over the next 25 years, comparative longitudinal survey data on child and young adult well-being. The infrastructure developed by ECDP will subsequently coordinate the first Europe wide cohort survey, which we name EuroCohort. ", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["INFRADEV-01-2017 - Design Studies"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["777449"], "Call_for_Proposal": ["H2020-INFRADEV-2017-1"]}, -{"Partners": ["ECOLE D'ECONOMIE DE PARIS", "UNIVERSITEIT ANTWERPEN", "JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN", "ERASMUS UNIVERSITEIT ROTTERDAM", "UNIWERSYTET EKONOMICZNY WE WROCLAWIU", "THE QUEEN'S UNIVERSITY OF BELFAST", "KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW", "UNIVERSIDAD CARLOS III DE MADRID", "UNIVERSITE DE ROUEN NORMANDIE", "INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE RENNES", "GESIS-LEIBNIZ-INSTITUT FUR SOZIALWISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 3 385 610"], "Project_Title": ["Historical high-quality company-level data for Europe"], "Total_Cost": ["EUR 3 385 860"], "Country": ["France", "Belgium", "Germany", "Netherlands", "Poland", "United Kingdom", "Netherlands", "Spain", "France", "France", "Germany"], "Project_ACR": ["EURHISFIRM"], "Technology_Description": "EURHISFIRM designs a world-class research infrastructure (RI) to connect, collect, collate, align, and share detailed, reliable, and standardized long-term financial, governance, and geographical data on European companies. EURHISFIRM enables researchers, policymakers, and other stakeholders to develop and evaluate effective strategies to promote investment, economic growth and job creation. The RI provides the tools for long-term analysis highlighting the dynamics of the past and the way those dynamics structure our present and future. A few large stand-alone long-term databases have been built in Europe so far, while important resources have been invested into scattered and dispersed historical datasets. EURHISFIRM develops innovative models and technologies to spark a \u201cBig data\u201d revolution in historical social sciences and valorize Europe\u2019s cultural heritage. These technologies match and collate historical data, and connect them to recent ones. They bring the next generation of data extraction and enrichment systems from digitized historical sources and web-based resources. The scaling up in the variety, quantity and quality of long-term data changes the way of conducting scientific enquiry in the historical social sciences. EURHISFIRM constitutes a vibrant and large users\u2019 community around the innovative data and services provided. The 2016 ESFRI Roadmap identifies Big Data, interdisciplinarity and innovative ways to disseminate research products as the main science drivers for RIs in the Social Sciences and Humanities. It recognizes the need and the opportunity for RIs providing access to the European Cultural Heritage and innovative methods to analyze and integrate information extracted to broad communities. EURHISFIRM fulfills this mission in close cooperation with ESFRI Landmark CESSDA and other existing RIs in the field of Arts and Humanities, like DARIAH, within the Research Data Alliance.", "To": ["2021-03-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["INFRADEV-01-2017 - Design Studies"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2018-04-01"], "Project_ID": ["777489"], "Call_for_Proposal": ["H2020-INFRADEV-2017-1"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "METEOROLOGISK INSTITUTT", "ILMATIETEEN LAITOS", "INSTITUT NATIONAL DE L ENVIRONNEMENT ET DES RISQUES INERIS", "KONINKLIJK NEDERLANDS METEOROLOGISCH INSTITUUT-KNMI", "STOCKHOLMS UNIVERSITET", "UNIVERSITE GRENOBLE ALPES", "LEIBNIZ INSTITUT FUER TROPOSPHAERENFORSCHUNG e.V.", "UNIVERSIDAD DE CHILE", "UNIVERSIDADE DE SAO PAULO", "UNIVERSIDAD NACIONAL DE COLOMBIA", "COMISION NACIONAL DE ENERGIA ATOMICA", "UNIVERSIDAD MAYOR DE SAN ANDRES", "UNIVERSIDAD TECNICA FEDERICO SANTA MARIA", "INSTITUTO VENEZOLANO DE INVESTIGACIONES CIENTIFICAS", "UNIVERSIDAD NACIONAL AUTONOMA DE MEXICO", "UNIVERSIDAD DE PUERTO RICO"], "EU_Contribution": ["EUR 1 188 000"], "Project_Title": ["Prediction of Air Pollution in Latin America"], "Total_Cost": ["EUR 1 467 000"], "Country": ["Germany", "France", "Norway", "Finland", "France", "Netherlands", "Sweden", "France", "Germany", "Chile", "Brazil", "Colombia", "Argentina", "Bolivia", "Chile", "Venezuela", "Mexico", "United States"], "Project_ACR": ["PAPILA"], "Technology_Description": "The overall objective of the PAPILA project (Prediction of Air Pollution in Latin America and the Caribbean) is to establish a sustained network of partners with complementary expertise, which will develop and implement an analysis and forecast system for air quality with downscaling capability for Latin America and the Caribbean region (LAC region), and assess the impact of air pollution (background and peaks) on health and on the economy. This forecast system will help decision-makers improve air quality and public health, and avoid the occurrence of acute air pollution episodes, particularly in urban areas.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Other", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["777544"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["STICHTING ASTRON, NETHERLANDS INSTITUTE FOR RADIO ASTRONOMY", "UNIVERSITAET BIELEFELD", "CENTRUM BADAN KOSMICZNYCH POLSKIEJ AKADEMII NAUK", "STICHTING INTERNATIONAL LOFAR TELESCOPE", "OBSERVATOIRE DE PARIS", "CHALMERS TEKNISKA HOEGSKOLA AB", "SCIENCE AND TECHNOLOGY FACILITIES COUNCIL", "THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN"], "EU_Contribution": ["EUR 2 998 750"], "Project_Title": ["LOFAR for Space Weather"], "Total_Cost": ["EUR 2 998 750"], "Country": ["Netherlands", "Germany", "Poland", "Netherlands", "France", "Sweden", "United Kingdom", "Ireland"], "Project_ACR": ["LOFAR4SW"], "Technology_Description": "TThe LOFAR for Space Weather (LOFAR4SW) design proposal will deliver the full conceptual and technical design for creating a new leading-edge European research facility for space weather science.", "To": ["2021-05-31, ongoing project"], "Meta": [""], "Topic_s": ["INFRADEV-01-2017 - Design Studies"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Netherlands"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["777442"], "Call_for_Proposal": ["H2020-INFRADEV-2017-1"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "LABORATORIO DE INSTRUMENTACAO E FISICA EXPERIMENTAL DE PARTICULAS", "ISTITUTO NAZIONALE DI FISICA NUCLEARE", "INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK", "KARLSRUHER INSTITUT FUER TECHNOLOGIE", "UNIVERSITAT POLITECNICA DE VALENCIA", "CESNET ZAJMOVE SDRUZENI PRAVNICKYCH OSOB", "USTAV INFORMATIKY, SLOVENSKA AKADEMIA VIED", "ATOS SPAIN SA", "HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH"], "EU_Contribution": ["EUR 2 988 750"], "Project_Title": ["Designing and Enabling E-infrastructures for intensive Processing in a Hybrid DataCloud"], "Total_Cost": ["EUR 2 988 750"], "Country": ["Spain", "Portugal", "Italy", "Poland", "Germany", "Spain", "Czech Republic", "Slovakia", "Spain", "Germany"], "Project_ACR": ["DEEP-HybridDataCloud"], "Technology_Description": "The key concept proposed in the DEEP Hybrid DataCloud project is the need to support intensive computing techniques that require specialized HPC hardware, like GPUs or low latency interconnects, to explore very large datasets. A Hybrid Cloud approach enables the access to such resources that are not easily reachable by the researchers at the scale needed in the current EU e-infrastructure. ", "To": ["2020-04-30, ongoing project"], "Meta": [""], "Topic_s": ["EINFRA-21-2017 - Platform-driven e-infrastructure innovation"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations"], "From": ["2017-11-01"], "Project_ID": ["777435"], "Call_for_Proposal": ["H2020-EINFRA-2017"]}, -{"Partners": ["\"NATIONAL CENTER FOR SCIENTIFIC RESEARCH \"\"DEMOKRITOS\"\"\"", "ISTITUTO NAZIONALE DI GEOFISICA E VULCANOLOGIA", "THE UNIVERSITY OF EDINBURGH", "CENTRE EUROPEEN DE RECHERCHE ET DE FORMATION AVANCEE EN CALCUL SCIENTIFIQUE", "THE UNIVERSITY OF LIVERPOOL", "KONINKLIJK NEDERLANDS METEOROLOGISCH INSTITUUT-KNMI", "ETHNIKO DIKTYO EREVNAS TECHNOLOGIAS AE", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.", "ATHINA-EREVNITIKO KENTRO KAINOTOMIAS STIS TECHNOLOGIES TIS PLIROFOFORIAS, TON EPIKOLNONION KAI TIS GNOSIS"], "EU_Contribution": ["EUR 2 957 500"], "Project_Title": ["Delivering Agile Research Excellence on European e-Infrastructures"], "Total_Cost": ["EUR 2 957 500"], "Country": ["Greece", "Italy", "United Kingdom", "France", "United Kingdom", "Netherlands", "Greece", "Germany", "Greece"], "Project_ACR": ["DARE"], "Technology_Description": "DARE (Delivering Agile Research Excellence on European e-Infrastructures) aims to provide scientific communities with a unifying hyper-platform and development context to allow for user-friendly and reproducible carrying out of huge data-driven experiments, and rapid prototyping. DARE specifically addresses the requirements of innovating teams of research developers and scientists, who work on the intersection of software engineering and scientific domains, and on data, complexity and computing extremes.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["EINFRA-21-2017 - Platform-driven e-infrastructure innovation"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Greece"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["777413"], "Call_for_Proposal": ["H2020-EINFRA-2017"]}, -{"Partners": ["ISTITUTO NAZIONALE DI FISICA NUCLEARE", "UNIVERSIDAD DE CANTABRIA", "STIFTUNG DEUTSCHES ELEKTRONEN-SYNCHROTRON DESY", "EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "AKADEMIA GORNICZO-HUTNICZA IM. STANISLAWA STASZICA W KRAKOWIE", "ECRIN EUROPEAN CLINICAL RESEARCH INFRASTRUCTURE NETWORK", "STICHTING EGI"], "EU_Contribution": ["EUR 3 077 000"], "Project_Title": ["eXtreme DataCloud"], "Total_Cost": ["EUR 3 396 875"], "Country": ["Italy", "Spain", "Germany", "Switzerland", "France", "Poland", "France", "Netherlands"], "Project_ACR": ["XDC"], "Technology_Description": "The eXtreme DataCloud (XDC) project will develop scalable technologies for federating storage resources and managing data in highly distributed computing environments. The services provided will be capable of operating at the unprecedented scale required by the most demanding, data intensive, research experiments in Europe and Worldwide. XDC will be based on existing tools (TRL8+) that the project will enrich with new functionalities and plugins already available as prototypes (TRL6). The targeted platforms are the current and next generation e-Infrastructures deployed in Europe, such as the European Open Science Cloud (EOSC), the European Grid Infrastructure (EGI), the Worldwide LHC Computing Grid (WLCG) and the computing infrastructures that will be funded by the upcoming H2020 EINFRA-12 call. The main high-level topics addressed by the project include: federation of storage resources with standard protocols, smart caching solutions, policy driven data management based on Quality of Service, data lifecycle management, metadata handling and manipulation, data preprocessing and encryption during ingestion, optimized data management based on access patterns. All the developments will be driven and tested against real life use cases provided by the consortium partners representing research communities belonging to a variety of scientific domains: Life Science, Astrophysics, High Energy Physics, Photon Science and Clinical Research. The XDC software will be released as Open Source platforms available for general exploitation.", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["EINFRA-21-2017 - Platform-driven e-infrastructure innovation"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Other", "Other"], "From": ["2017-11-01"], "Project_ID": ["777367"], "Call_for_Proposal": ["H2020-EINFRA-2017"]}, -{"Partners": ["INSTYTUT PODSTAWOWYCH PROBLEMOW TECHNIKI POLSKIEJ AKADEMII NAUK", "AGENZIA PER LA PROMOZIONE DELLA RICERCA EUROPEA", "NATIONAL AUTHORITY FOR TECHNOLOGICAL INNOVATION", "NEMZETI KUTATASI FEJLESZTESI ES INNOVACIOS HIVATAL", "VEREIN EURESEARCH", "SIHTASUTUS EESTI TEADUSAGENTUUR", "AGENCIJA ZA MOBILNOST I PROGRAME EUROPSKE UNIJE", "ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS", "IDRYMA PROOTHISIS EREVNAS", "UNIVERSITATEA DE STIINTE AGRICOLE SI MEDICINA VETERINARA A BANATULUI REGELE MIHAI I AL ROMANIEI DIN TIMISOARA", "TURKIYE BILIMSEL VE TEKNOLOJIK ARASTIRMA KURUMU", "IRISH UNIVERSITIES ASSOCIATION", "OESTERREICHISCHE FORSCHUNGSFOERDERUNGSGESELLSCHAFT MBH", "BULGARIAN ACADEMY OF SCIENCES", "ACADEMY OF SCIENTIFIC RESEARCH AND TECHNOLOGY ASRT", "DEUTSCHES ZENTRUM FUER LUFT - UND RAUMFAHRT EV", "FUNDACION ESPANOLA PARA LA CIENCIA Y LA TECNOLOGIA", "MINISTERIO DE EDUCACION Y CULTURA", "RANNSOKNAMIDSTOD ISLANDS"], "EU_Contribution": ["EUR 1 800 000"], "Project_Title": ["Network of the Marie Sk\u0142odowska-Curie Action National Contact Points for the mobile scientific and innovation community"], "Total_Cost": ["EUR 1 800 000"], "Country": ["Poland", "Italy", "Israel", "Hungary", "Switzerland", "Estonia", "Croatia", "Greece", "Cyprus", "Romania", "Turkey", "Ireland", "Austria", "Bulgaria", "Egypt", "Germany", "Spain", "Uruguay", "Iceland"], "Project_ACR": ["Net4MobilityPlus"], "Technology_Description": "The National Contact Points (NCPs) play an important role in assisting potential applicants and project beneficiaries during their journey through the Horizon 2020 instruments. According to the EC Guide on the NCPs principles, they are responsible for raising awareness about available funding opportunities; advising and training potential applicants in the preparation, submission and follow-up of their grant proposals; providing support during the project execution as well as giving feedback on difficulties in the programme implementation. Thus, the NCPs constitute the main interface between the Programme and the R&I community in Europe and beyond, as well as between them and the EC. Basing on such a position, Net4Mobility+ aims at strengthening the consistency and professionalism of the NCPs for Marie Sk\u0142odowska-Curie Actions \u2013 part of H2020 supporting international and intersectoral mobility and researchers\u2019 career development. The consortium of 19 beneficiaries and 6 associated partners representing the Member States, Associated and Third countries will execute a set of activities tailored to the nature of MSCA and to priorities and capacity of the entire NCPs network, including needs of the \u201cwidening countries\u201d. The focus on sharing expertise and good practices, transfer of knowledge to less experienced NCPs, joint support provided on a daily basis, enhancing knowledge and skills, broadening tools and methodology will facilitate the improvement of the overall professionalism of NCP services across and outside Europe. Outcomes of project events (training, twinning, seminars), jointly developed materials (guides, recommendations) and communication and dissemination platform (website, social media) will result in lowering entry barriers for newcomers, simplifying access to MSCA calls and raising the quality of applications. For reaching the project objectives and ensuring the impact, the consortium will work closely, keeping high management and quality standards.", "To": ["2021-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-NCP-2017 - MSCA National Contact Points"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Poland"], "Activity": ["Research Organisations", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Other", "Other", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Other", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2018-03-01"], "Project_ID": ["785632"], "Call_for_Proposal": ["H2020-MSCA-NCP-2017"]}, -{"Partners": ["GOETEBORGS UNIVERSITET", "GOETEBORGS UNIVERSITET"], "EU_Contribution": ["EUR 149 700,75"], "Project_Title": ["Identification of novel inhibitors to prevent microbial production of pro-diabetic metabolites"], "Total_Cost": ["EUR 149 700,75"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["Drug the bug"], "Technology_Description": "The gut microbiota has been associated with metabolic diseases, such as type 2 diabetes. In my ERC consolidator award we demonstrated that the gut microbiota is altered following bariatric surgery and that the altered microbiota may be directly linked to some of the metabolic improvements observed following surgery. Interestingly, improved metabolism was associated with altered metabolite production capacity from the microbiota and we observed that a metabolite, imidazole propionate, was reduced after surgery. In associated projects we have demonstrated that imidazole propionate is associated with type 2 diabetes in humans and induce insulin resistance in primary hepatocytes and when injected into mice. Imidazole propionate is synthesized by the microbial enzyme UrdA from histidine. This POC will explore the potential of identifying inhibitors of UrdA to reduce production of imidazole propionate and thereby improve insulin sensitivity. If successful we envision a new class of diabetes medication based on the concept of drug the bug.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["780659"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UPPSALA UNIVERSITET", "KUNGLIGA TEKNISKA HOEGSKOLAN", "EUROPEAN SPALLATION SOURCE ERIC", "UNIVERSITY OF CUKUROVA", "UNIVERSIDAD AUTONOMA DE MADRID", "\"NATIONAL CENTER FOR SCIENTIFIC RESEARCH \"\"DEMOKRITOS\"\"\"", "ISTITUTO NAZIONALE DI FISICA NUCLEARE", "RUDER BOSKOVIC INSTITUTE", "SOFIISKI UNIVERSITET SVETI KLIMENT OHRIDSKI", "LUNDS UNIVERSITET", "AKADEMIA GORNICZO-HUTNICZA IM. STANISLAWA STASZICA W KRAKOWIE", "EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH", "UNIVERSITE DE GENEVE", "UNIVERSITY OF DURHAM"], "EU_Contribution": ["EUR 2 999 018"], "Project_Title": ["Feasibility Study for employing the uniquely powerful ESS linear accelerator to generate an intense neutrino beam for leptonic CP violation discovery and measurement."], "Total_Cost": ["EUR 4 671 583,68"], "Country": ["France", "Sweden", "Sweden", "Sweden", "Turkey", "Spain", "Greece", "Italy", "Croatia", "Bulgaria", "Sweden", "Poland", "Switzerland", "Switzerland", "United Kingdom"], "Project_ACR": ["ESSnuSB"], "Technology_Description": "After the Big Bang, matter and antimatter were produced in equal quantities through materialization of the huge energy released. Observations show that today, however, there is a nearly total absence of antimatter in the Universe. The occurrence of Charge-Parity Violation (CPV) is a necessary condition for an explanation of this absence. CPV has already been observed in the quark sector but the measured amount is insufficient to explain the observed matter-antimatter asymmetry. Recent neutrino oscillation measurements indicate that the discovery of neutrino CPV becomes an important candidate to explain the observed matter dominance in the Universe. The goal of ESSnuSB project is to discover and measure neutrino CPV with unprecedented sensitivity. The ESSnuSB concept takes advantage of two outstanding opportunities. The first is the construction in Europe of the European Spallation Source, ESS, the world\u2019s most intense proton source, with a beam power almost one order of magnitude higher than any other accelerator. The second is the recently measured unexpectedly large value of the oscillation mixing angle \u03b813. The latter fact implies that to obtain maximum sensitivity, the neutrino detector shall be placed at the second neutrino oscillation maximum, not at the first as implemented by the other proposed experiments. The Garpenberg mine in Sweden, in which it is proposed to install the underground neutrino detector, is situated at a distance from ESS that corresponds to the second maximum. The COST Action CA15139, \u201cCombining forces for a novel European facility for neutrino-antineutrino symmetry-violation discovery\u201d, already recognizes the necessity to have neutrino facilities in Europe. The goal of the ESS\u03bdSB H2020 Design Study is to organize European physicists and accelerator engineers in co-operation with the ESS Laboratory and the Garpenberg Mining Company to study and produce a Conceptual Design Report for the ESSnuSB project.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["INFRADEV-01-2017 - Design Studies"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["777419"], "Call_for_Proposal": ["H2020-INFRADEV-2017-1"]}, -{"Partners": ["INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE", "INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Innovative Antibiotics to target drug-resistant microbes"], "Total_Cost": ["EUR 150 000"], "Country": ["France", "France"], "Project_ACR": ["D_Bug"], "Technology_Description": "Antibiotic resistance has become a major public health threat in Europe and the United States where resistant bacteria are directly responsible for ten of thousands deaths per year. The D_Bug project aims to develop innovative antibiotics to target drug-resistant microbes.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-11-01"], "Project_ID": ["780383"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["ISTITUTO EUROPEO DI ONCOLOGIA SRL", "ISTITUTO EUROPEO DI ONCOLOGIA SRL"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Immuno-targeting of human AML quiescent cells by a novel phage display approach."], "Total_Cost": ["EUR 150 000"], "Country": ["Italy", "Italy"], "Project_ACR": ["ITHACA"], "Technology_Description": "One main objective of our ERC Advanced Grant project (InMec, No 341131) was to determine how cancer stem cells (CSCs) contribute to tumour growth, and the relative impact of quiescent versus proliferative CSCs. ", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Italy"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-01-01"], "Project_ID": ["779802"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["MAGYAR TUDOMANYOS AKADEMIA RENYI ALFRED MATEMATIKAI KUTATOINTEZET", "MAGYAR TUDOMANYOS AKADEMIA RENYI ALFRED MATEMATIKAI KUTATOINTEZET"], "EU_Contribution": ["EUR 1 386 363,52"], "Project_Title": ["Noise-Sensitivity Everywhere"], "Total_Cost": ["EUR 1 386 363,52"], "Country": ["Hungary", "Hungary"], "Project_ACR": ["NOISE"], "Technology_Description": "Noise-sensitivity of a Boolean function with iid random input bits means that resampling a tiny proportion of the input makes the output unpredictable. This notion arises naturally in computer science, but perhaps the most striking example comes from statistical physics, in large part due to the PI: the macroscopic geometry of planar percolation is very sensitive to noise. This can be recast in terms of Fourier analysis on the hypercube: a function is noise sensitive iff most of its Fourier weight is on \"high energy\" eigenfunctions of the random walk operator.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Hungary"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-02-01"], "Project_ID": ["772466"], "Call_for_Proposal": ["ERC-2017-COG"]}, -{"Partners": ["JUSTUS-LIEBIG-UNIVERSITAET GIESSEN", "JUSTUS-LIEBIG-UNIVERSITAET GIESSEN"], "EU_Contribution": ["EUR 1 991 387,50"], "Project_Title": ["Nuclear mRNA Packaging and mRNP Architecture"], "Total_Cost": ["EUR 1 991 387,50"], "Country": ["Germany", "Germany"], "Project_ACR": ["mRNP-PackArt"], "Technology_Description": "An important step of gene expression is the formation of a messenger ribonucleoprotein particle (mRNP). The messenger RNA (mRNA) is synthesized by RNA polymerase II transcribing a protein-coding gene. The mRNA is processed, i.e. capped, spliced and polyadenylated, and packaged into an mRNP by binding of RNA-binding proteins (RBPs). The RBPs bound to the mRNA are essential for the stability of the mRNP, control nuclear mRNA export and often determine cytoplasmic processes such as mRNA localization, translation and decay. Thus, the formation and composition of an mRNP is important for the posttranscriptional control of gene expression. Despite its essential nature, the mechanism of nuclear mRNP packaging and the architecture of an mRNP are still poorly understood due to the fact that mRNPs contain many different mRNAs. The overall goal of this proposal is to elucidate the mechanism of mRNP formation and the molecular structure of an mRNP. Specifically,", "To": ["2023-05-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-06-01"], "Project_ID": ["772049"], "Call_for_Proposal": ["ERC-2017-COG"]}, -{"Partners": ["UNIVERSITY OF LEEDS", "UNIVERSITY OF LEEDS"], "EU_Contribution": ["EUR 1 965 623"], "Project_Title": ["Deforestation \u2013 Climate \u2013Atmospheric composition \u2013 Fire interactions and feedbacks"], "Total_Cost": ["EUR 1 965 623"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["DECAF"], "Technology_Description": "Extensive and ongoing tropical deforestation and degradation have important environmental impacts. Smoke aerosol from deforestation fires degrades air quality, but the effects are poorly quantified. Deforestation alters rainfall through changes in the land surface and through changes to atmospheric aerosol. The magnitude and the sign of the rainfall response is not clear, because of poor process-level understanding and because previous attempts have studied land surface and aerosol responses separately. The impacts of deforestation on atmospheric composition and climate cause a complex set of biosphere interactions resulting in potential Earth system feedbacks. These feedbacks have not yet been quantified and so their importance is not known. The full impact of deforestation on air quality, climate and the Earth System may have been underestimated because there have been no integrated studies of the combined interactions and feedbacks between deforestation and the Earth system. DECAF is the first integrated study of the combined interactions and feedbacks between tropical deforestation, fire, atmospheric composition and climate. To address this important challenge, DECAF will exploit new information from in-situ and satellite observations in combination with state-of-the-art numerical models. DECAF will deliver improved process-level knowledge of the impacts of deforestation on atmospheric composition and climate and a step change in our understanding of the interactions and feedbacks between deforestation, atmospheric composition and climate. New understanding will inform the development of climate and Earth System Models and will facilitate new climate and Earth system assessments.", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["771492"], "Call_for_Proposal": ["ERC-2017-COG"]}, -{"Partners": ["INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE", "INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE"], "EU_Contribution": ["EUR 149 866"], "Project_Title": ["Vision and Hearing In Action Laboratory"], "Total_Cost": ["EUR 149 866"], "Country": ["France", "France"], "Project_ACR": ["VHIALab"], "Technology_Description": "The objective of VHIALab is the development and commercialization of software packages enabling a robot companion to robustly interact with multiple users. VHIALab builds on the scientific findings of ERC VHIA (February 2014 - January 2019). Solving the problems of audio-visual analysis and interaction opens the door to multi-party and multi-modal human-robot interaction (HRI). In contrast to well investigated single-user spoken dialog systems, these problems are extremely challenging because of noise, interferences and reverberation present in far-field acoustic signals, overlap of speech signals from two or more different speakers, visual clutter due to complex situations, people appearing and disappearing over time, speakers turning their faces away from the robot, etc. For these reasons, today's companion robots have extremely limited capacities to naturally interact with a group of people. Current vision and speech technologies only enable single-user face-to-face interaction with a robot, benefitting from recent advances in speech recognition, face recognition, and lip reading based on close-field microphones and cameras facing the user. As a consequence, although companion robots have an enormous commercialization potential, they are not yet available on the consumer market. The goal of VHIALab is to further reduce the gap between VHIA's research activities and the commercialization of companion robots with HRI capabilities. We propose to concentrate onto the problem of audio-visual detection and tracking of several speakers, to develop an associated software platform, to interface this software with a commercially available companion robot, and to demonstrate the project achievements based on challenging practical scenarios.", "To": ["2019-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-02-01"], "Project_ID": ["767064"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["THE UNIVERSITY OF NOTTINGHAM", "RISC SOFTWARE GMBH", "UNIVERSIDADE DO PORTO", "AIRBUS DEFENCE AND SPACE GMBH"], "EU_Contribution": ["EUR 1 266 011,28"], "Project_Title": ["European industrial doctorate for efficient multidisciplinary design Optimization ofMultifunctional Aerospace Composite Structures"], "Total_Cost": ["EUR 1 266 011,28"], "Country": ["United Kingdom", "Austria", "Portugal", "Germany"], "Project_ACR": ["OptiMACS"], "Technology_Description": "Modern aeronautical structures are increasingly made of composite materials due to their well-known benefits. Optimizing the design of aerospace composites vis-\u00e0-vis the entire range of operational constraints (i.e. reliability, stability, strength, weight, noise, manufacturability and cost) to which the aircraft structures are subject, results in a particularly challenging task for the structural designer. Despite the volume of recent work dedicated to new Multidisciplinary Design Optimization (MDO) models and techniques, the \u2018No free lunch theorem in optimisation\u2019 is constantly confirmed.", "To": ["2022-04-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-05-01"], "Project_ID": ["764650"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE"], "EU_Contribution": ["EUR 1 994 385"], "Project_Title": ["Imaging, Spectroscopy and Control of Quantum states in advanced Materials"], "Total_Cost": ["EUR 1 994 385"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["ISCQuM"], "Technology_Description": "Atomic confinement in 2D materials, topological protection in strong spin-orbit coupling systems or chiral magnets, all result in spin/charge textured states of matter. For example skyrmions, a whirling distribution of spins, behave as individual particles which controlled creation/annihilation/motion is of great importance in spintronics. To achieve control over skyrmions, or more generally over the constituents of disordered elastic media (vortices in superconductors, domain walls in magnets to name a few), the fundamental interplay between short-range and long-range interactions, influenced by topological protection, disorder and confinement, has to be understood and manipulated. This project aims at controlling with electromagnetic pulses a handful of charges and spins in nanostructured materials to be filmed with nm/fs resolution by time-resolved Transmission Electron Microscopy. I propose to image and shape confined electromagnetic fields (plasmons) in nanostructured novel materials. With this ability, we will implement/demonstrate the ultrafast writing and erasing of individual skyrmions in topological magnets. These experiments will enable the fundamental investigation of defects in topological networks and possibly seed new ideas for application in ultradense and ultrafast data storage devices. Similarly, pinning of vortices in type II superconductors will be controlled by light and imaged, gaining new insights into out of equilibrium superconductivity. In my laboratory, shaping and filming plasmonic fields down to the nm-fs scales have been demonstrated, as well as laser-writing and imaging skyrmions in nanostructures. ISCQuM will allow implementing crucial advances: i) extending our photoexcitation to the far-infrared for creating few-cycles electromagnetic pulses and exciting structural or electronic collective modes; ii) upgrading our detection to higher sensitivity and spatial resolution, extending our ability to image spin and charge distributions.", "To": ["2023-06-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-07-01"], "Project_ID": ["771346"], "Call_for_Proposal": ["ERC-2017-COG"]}, -{"Partners": ["BIRMINGHAM CITY UNIVERSITY", "SINGULARLOGIC ROMANIA COMPUTER APPLICATIONS SRL"], "EU_Contribution": ["EUR 761 644,44"], "Project_Title": ["Internet of Thing for Smart Water Innovative Networks"], "Total_Cost": ["EUR 761 644,44"], "Country": ["United Kingdom", "Romania"], "Project_ACR": ["IoT4Win"], "Technology_Description": "The IoT4Win will establish a European Industrial Doctorates (EID) training program and extend the traditional academic research training setting, equipping researchers with right combination of research-related and transferable competences, joint research training programme combines an interdisciplinary expertise of European research group, industry partners and user organisations, bring together all required knowledge, skills, and stakeholders to offer a comprehensive set of transferable skills and a training programme on ICT, data science and water engineering, including industry practice and longer-term benefit in further industrial partner collaborations and further knowledge transfer. IoT4Win will respond to well defined and interdisciplinary scientific questions and challenges on IoTs for Smart Water Network (SWN) technological area cooperating to recruit 3 ESRs to undertake research in the context of a joint research training on concepts and methodologies of IoT enabled SWN towards the PhD. IoT4Win designs 3 individual and personalised research projects covering the core SWN research areas, i.e. smart sensing and trusted communication within energy limited heterogeneous devices in IoT enabled urban water environment; dynamic sensor web and interoperable open platform with Integrated Knowledge Management for smart water networks; data security and intelligence in IoT enabled SWN. The interdisciplinary collaborations and cross industrial interactions between ICT and water sector, will expose researchers to the academic, non-academic sectors. By combining three projects, an interoperable, secure and intelligent underlying technology leading to an open platform for IoT enabled SWN applications will be developed. This platform will then be applied to and evaluated in the real water scenarios with our end user industrial partner, leading to a specialised technology platform for SWN and a best-practice smart water network demonstrator.", "To": ["2022-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-03-01"], "Project_ID": ["765921"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["ViDaR: R-enabled large-scale data analytics in ViDa"], "Total_Cost": ["EUR 150 000"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["ViDaR"], "Technology_Description": "In this project we will build ViDaR, an interface for integrating R with ViDa. R is among the leading data analytics environments (the leading open-source), and is heavily used by data and domain scientists and data analysts in their daily routine. ViDa, developed by an ERC grant, is the state-of-the-art query engine for raw data. It relies on data virtualization, i.e., abstracting data out of its form and manipulating it regardless of the way it is stored or structured, to enable efficient, scalable, querying and manipulation of data in-situ, at their raw format and shape. Integration of ViDa with R will have a positive impact on both systems. For ViDa, it will provide capabilities for data exploration, visualization, mining and analytics, as well as powerful libraries for numerical and statistical computing, thereby substantially growing its user base. For R, it will increase its scale and performance, and reduce the time and effort spent by data scientists on tedious data management tasks. The resulting solution will serve as a proof-of-concept of ViDa\u2019s performance, capabilities, and flexibility for integration with any third-party software that needs to manage vast amounts of raw data.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["768910"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["TECHNISCHE UNIVERSITEIT DELFT", "TECHNISCHE UNIVERSITEIT DELFT", "STICHTING VUMC"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["An EEG calibration toolkit for monitoring rehabilitation of stroke patients."], "Total_Cost": ["EUR 150 000"], "Country": ["Netherlands", "Netherlands", "Netherlands"], "Project_ACR": ["MRI4DEEG"], "Technology_Description": "An EEG calibration toolkit for monitoring rehabilitation of stroke patients", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["767235"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["TECHNISCHE UNIVERSITEIT EINDHOVEN", "Philips GmbH"], "EU_Contribution": ["EUR 766 122,84"], "Project_Title": ["Open Ground Truth Training Network : Magnetic resonance image simulationfor training and validation of image analysis algorithms"], "Total_Cost": ["EUR 766 122,84"], "Country": ["Netherlands", "Germany"], "Project_ACR": ["OpenGTN"], "Technology_Description": "This action aims to optimally prepare three young researchers for the evolving medical imaging world by offering a unique set of targeted interdisciplinary training and research assignments in the areas of anatomy, pathology, imaging techniques, quantitative image analysis and segmentation, Magnetic Resonance (MR) physics and MR image simulation. ", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-01-01"], "Project_ID": ["764465"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["UNIVERSITAET REGENSBURG", "UNIVERSITAET REGENSBURG"], "EU_Contribution": ["EUR 1 955 846,25"], "Project_Title": ["Metal-Mediated Methods for the Functionalization of White Phosphorus (P4)"], "Total_Cost": ["EUR 1 955 846,25"], "Country": ["Germany", "Germany"], "Project_ACR": ["FunctionalP4"], "Technology_Description": "Organophosphorus compounds are an important and industrially relevant class of molecules with numerous uses, e.g. as reagents in organic synthesis, ligands in catalytically active metal complexes, and in pest control. State-of-the-art synthesis methods for all these valuable and useful compounds rely on an atom inefficient and hazardous multi-step procedure involving the oxidation of white phosphorus (P4) with toxic chlorine gas. Less wasteful and more environmentally benign methods are highly desirable, but transformations of white phosphorus directly into organophosphorus compounds are hardly developed.", "To": ["2023-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["772299"], "Call_for_Proposal": ["ERC-2017-COG"]}, -{"Partners": ["UNIVERSITATEA TEHNICA CLUJ-NAPOCA", "SIEMENS INDUSTRY SOFTWARE NV", "Brose Fahrzeugteile GmbH & Co. Kommanditgesellschaft, Wurzburg", "UNIVERSITE LIBRE DE BRUXELLES", "ICPE SA"], "EU_Contribution": ["EUR 1 409 046,14"], "Project_Title": ["European Industrial Doctorate on Next Generation for sustaINable auTomotive ElectRical ACtuaTion"], "Total_Cost": ["EUR 1 409 046,14"], "Country": ["Romania", "Belgium", "Germany", "Belgium", "Romania"], "Project_ACR": ["INTERACT"], "Technology_Description": "The trend for more electrified automotive applications (MEAA) asks for a new generation of automotive electrical actuation systems, allowing for a more efficient and environmentally friendly mobility and enhancing the driving experience, making it safer, more comfortable and sustainable. ", "To": ["2021-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["Romania"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-12-01"], "Project_ID": ["766180"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["UNIVERSIDAD POMPEU FABRA", "UNIVERSIDAD POMPEU FABRA"], "EU_Contribution": ["EUR 1 488 506"], "Project_Title": ["Resilience and Adaptation in Drylands. Identifying past water management practices for drought-resistant crops"], "Total_Cost": ["EUR 1 488 506"], "Country": ["Spain", "Spain"], "Project_ACR": ["RAINDROPS"], "Technology_Description": "RAINDROPS will investigate cultivation practices that support human resilience and adaptation in drylands, by developing an innovative and reliable methodology for the identification of water management practices from archaeobotanical remains. Irrigation, river floods or permanent water sources are often deemed necessary for cultivation to be practised in drylands. However, there are modern examples that testify to the existence of successful rain-fed cultivation systems, even in hyper-arid environments. Quantification of the extent of these practices in the past has the potential to dramatically change our understanding of human adaptation and agriculture. By establishing a protocol for the accurate identification of rain-fed cultivation, RAINDROPS will pave the way for the investigation of this practice in the past. Highly controlled data on phytolith ratios, and carbon, oxygen and silicon isotopes from macro- and micro-remains from experimental fields of finger millet [Eleusine coracana (L.) Gaertn.] and sorghum [Sorghum bicolor (L.) Moench] will be validated with ethnographic evidence before being applied to selected key archaeological case studies.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["759800"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["EUROPEAN MOLECULAR BIOLOGY LABORATORY", "EUROPEAN MOLECULAR BIOLOGY LABORATORY"], "EU_Contribution": ["EUR 1 228 125"], "Project_Title": ["In situ Structural Analysis of Molecular Crowding and Phase Separation"], "Total_Cost": ["EUR 1 228 125"], "Country": ["Germany", "Germany"], "Project_ACR": ["3DCellPhase-"], "Technology_Description": "This proposal brings together two fields in biology, namely the emerging field of phase-separated assemblies in cell biology and state-of-the-art cellular cryo-electron tomography, to advance our understanding on a fundamental, yet illusive, question: the molecular organization of the cytoplasm. ", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-02-01"], "Project_ID": ["760067"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA", "UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA"], "EU_Contribution": ["EUR 1 497 831"], "Project_Title": ["A neurosplenic pathway coupling Immunity and Hypertension"], "Total_Cost": ["EUR 1 497 831"], "Country": ["Italy", "Italy"], "Project_ACR": ["SymPAtHY"], "Technology_Description": "Hypertension (HTN) is a leading cause of morbidity and mortality worldwide. During past decades, several therapies have been developed to afford an optimal blood pressure (BP) regulation. However, the prevalence of uncontrolled HTN continues to rise, with a number of patients still resistant to all ongoing antihypertensive treatments, raising unsolved mechanistic challenges. In the last years, the most attractive novelty in HTN postulated that immune system has a crucial role in BP raising, as well as in end-organ damage. Several advances have been done in this field, but clear mechanistic explanations of how the immune system gets activated under hypertensive challenges is still unknown. It is becoming increasingly clear that, even in the regulation of body hemodynamic, the immune system and the autonomic nervous system serve as two major \u201csensory organs\u201d capable to be activated upon manifold hits that perturb homeostasis. SymPAtHY is a multidisciplinary strategy aimed at discovering how nervous and immune systems couple in HTN. The concept of this project is to dissect the neuro-immune pathway responsible for BP rising and end-organ damage. The articulation in 3 MAIN AIMS will allow to afford the mechanistic insights from different perspectives. The overall objectives are as follows: 1) Central nervous system relay station coupling immunity and hypertension. 2) Splenic immune mechanisms: from sympathetic drive to T cell egress; 3) T cells in target organs: from the spleen to vessels and kidney. The results of this strategy will unravel important new mechanistic insights in HTN and particularly will have significant implications for understanding how immunity and autonomic nervous system cooperate to rise BP. Based on the emerging view of HTN as an \u201cimmune disorder\u201d, we believe that this strategy will add decisive knowledge in this field that could pave the way for developing immunotherapies for the treatment of resistant HTN.", "To": ["2022-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["759921"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["INSTITUTO DE CIENCIAS SOCIAIS", "INSTITUTO DE CIENCIAS SOCIAIS"], "EU_Contribution": ["EUR 1 467 727"], "Project_Title": ["Rescuing seeds\u2019 heritage: engaging in a new framework of agriculture and innovation since the 18th century"], "Total_Cost": ["EUR 1 467 727"], "Country": ["Portugal", "Portugal"], "Project_ACR": ["ReSEED"], "Technology_Description": "Humanity is facing a huge challenge: how to feed a growing population in a sustainable way? Scientists from different fields are looking for answers and ReSEED aims to assist such endeavours. Solutions depend on one key issue: seeds. We can have appropriate soil, climate or technologies, however without proper seeds it is impossible to guarantee food production. As historiography has given little attention to the role of seed varieties, there are many gaps in scientific knowledge. I argue that long-term historical analysis is critical to provide the best answers to current questions. ReSEED examines the changing connections between seeds, environment and human action, the triangle that has always underpinned agriculture, since the 18th century. The main objectives are as follows. 1) To map geographical changes in local crop distribution, paying attention to the new seeds made available by Columbian Exchange. 2) To outline which were the social networks supporting the circulation and cultivation of edible seed varieties, and at later date, checking how they articulated with state services. 3) To identify human factors that contribute to reducing, increasing, maintaining or restoring regional agro-biodiversity. 4) To assess the impacts of national and international decisions on local management of the triangle, mainly on farmers\u2019 innovation. 5) To re-examine the long-term dynamics behind various European agricultural modernization itineraries. Based on innovative interdisciplinary and transdisciplinary methodologies, I build robust empirical research on the case of Iberian Peninsula in connection to empires, which allows thorough comparisons with other regions in Europe and beyond. ReSEED promotes strategies for win-win environmental/society outcomes, linking edible seeds to places and to innovations needed for food production. This is crucial to better understand how historical experiences can contribute to create solutions that ensure sustainable futures.", "To": ["2023-05-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Portugal"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-06-01"], "Project_ID": ["760090"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["CONSIGLIO NAZIONALE DELLE RICERCHE", "CONSIGLIO NAZIONALE DELLE RICERCHE"], "EU_Contribution": ["EUR 1 050 000"], "Project_Title": ["SENSING CELL-CELL INTERACTION HETEROGENEITY IN 3D TUMOR MODELS:TOWARDS PRECISION MEDICINE"], "Total_Cost": ["EUR 1 050 000"], "Country": ["Italy", "Italy"], "Project_ACR": ["INTERCELLMED"], "Technology_Description": "This project aims to investigate the role of potassium (K+), protons (H+) and oxygen (O2) gradients in the extracellular space of tumour cells grown in 3D cultures by using a combination of imaging, cell biology and in silico analyses. By embedding ratiometric fluorescent particle-based sensors within 3D scaffolds, the changes in target analyte concentrations can be monitored and used to study the interactions between tumour cells and stromal cells in 3D tumoroids/scaffolds and to monitor response of the cells to drug treatments. I first demonstrated successful fabrication of barcoded capsules for multiplex sensing of H+, K+, and Na+ ions. Next, I demonstrated the use of pH-sensing capsules as valid real time optical reporter tools to sense and monitor intracellular acidification in living cells. Thus, I can fabricate capsule sensors for investigating the role of key analytes that are involved in regulation of crucial physiological mechanisms. In addition, I successfully integrated pH-sensing capsules within 3D nanofibrous matrices and demonstrated their operation under pH switches. INTERCELLMED will engineer 3D scaffolds that do not only sense extracellular pH but are also able to sense K+ and O2 changes. To this aim, a novel set of anisotropic analyte-sensitive ratiometric capsules will be developed and applied for generating robust and flexible capsules-embedded sensing scaffolds. To validate the functions of the 3D sensing platform, cocoltures of tumour cells and stromal cells will be grown and their interaction and response to drug treatments will be studied by mapping the K+/H+/O2 gradients in and around the cell aggregates. Finally, the 3D sensing platform will be adapted for growing tumour tissue-derived cells that will be tested ex-vivo with anticancer dugs. Specific mathematical models of cellular interactions will be developed to represent the biological processes occurring within the 3D sensing platform.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-02-01"], "Project_ID": ["759959"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["THE UNIVERSITY OF EDINBURGH", "THE UNIVERSITY OF EDINBURGH"], "EU_Contribution": ["EUR 148 914"], "Project_Title": ["Rapid production of HUMAN MAST CELLS"], "Total_Cost": ["EUR 148 914"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["MASTFAST"], "Technology_Description": "Mast cells are involved in the allergic response, anaphylaxsis, wound healing and angiogenesis. When activated via IgE, damage/pathogen-induced molecules or complement components, the granules of mast cells release proteases. Dysregulation of mast cells is implicated in allergies of the skin and airways, autism, chronic fatigue syndrome, pain, mastocytoma and intestinal dysmotility. Strategies to limit the damaging effects of mast calls are needed. However, the development of novel treatments is hampered by the inability to grow mast cells rapidly and efficiently in culture. Bone marrow cell cultures typically take 12 weeks before mast cells are available for study. Even then, there are too few cells to use for drug discovery or patient-specific treatment strategies. Embryonic stem cells (ESC) represent an alternative method for the production of mast cells. An unexpected ground-breaking discovery from our ERC AdG 341096 studies aiming to produce hematopoietic stem cells, was the development of a novel method that instead produces large numbers of mast cells in a short time. Mouse ESC engineered with a unique reporter gene that allows for cell enrichment during a multi-step culture yields a homogenous population of phenotypic and functional connective tissue and mucosal mast cells. Within only 3 weeks large numbers of mast cells are generated. To translate this method for large scale rapid production of human mast cells we will 1) characterize unique human reporter ESCs made by Crispr/CAS9 state-of-the-art method; 2) optimize human mast cell production from reporter hESCs in a multi-step differentiation culture; 3) characterize/validate the function of hESC-derived mast cells (normal and mutant); 4) interact with industry to use hESC-derived mast cells for drug-discovery and studies of mast cell differentiation and dysfunction. Long-term goals include the development of mast cell treatment strategies for personalized medicine.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["768728"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["TECHNISCHE UNIVERSITEIT DELFT", "TECHNISCHE UNIVERSITEIT DELFT"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Selective Conversion of Water and CO2 Using Interfacial Electrochemical Engineering"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["WU TANG"], "Technology_Description": "The recycling of CO2 will play an important role in mitigating the energy and environmental problems that our future societies will no doubt face. Electrochemistry is a powerful technology that can make use of renewable electricity from solar and wind to power the transformation of CO2 and water to valuable chemicals and fuels. However, the electrochemical conversion of CO2 is not ready for large-scale deployment due to the poor activity, selectivity, and stability of the current catalysts used. The only way to be able to achieve better understanding of this complicated system is through careful characterization of the catalyst/electrolyte interface during electrochemical measurements, as well as the development of new theoretical models that include the effects of the electrolyte.", "To": ["2022-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["759743"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["CARDIFF UNIVERSITY", "CARDIFF UNIVERSITY"], "EU_Contribution": ["EUR 1 383 920"], "Project_Title": ["Data Justice: Understanding datafication in relation to social justice"], "Total_Cost": ["EUR 1 383 920"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["DATAJUSTICE"], "Technology_Description": "This project explores the meaning of social justice in an age of datafication. It is premised on two significant developments: 1) the shift to a focus on the collection and processing of massive amounts of data across social life and 2) the increasing concern with the societal implications of such processes. Whilst initial concern with the technical ability to \u2018datafy\u2019 and collect information on ever-more social activity focused on surveillance and privacy, increasing emphasis is being placed on the fact that data processes are not \u2018flat\u2019 and do not implicate everyone in the same way, but, rather, are part of a system of \u2018social sorting\u2019, creating new categories of citizens, and premised on an emerging order of \u2018have\u2019 and \u2018have nots\u2019 between data profilers and data subjects. In such a context, questions of social justice and datafication require detailed study. This project frames this research agenda around the notion of \u2018data justice\u2019. It will provide a European framework of study and take a holistic approach by situating research on data processes in the context of a) the concrete experiences and practices of particular communities; b) technological analyses of data sources, algorithmic process and data output; c) policy frameworks that relate to the interplay between digital rights and social and economic rights; and d) conceptual engagement with new social stratifications emerging with datafication. The project is ground-breaking in five different respects: i) it conceptually advances the meaning of social justice in a datafied society; ii) it shifts and challenges dominant understandings of data by highlighting its relation to social and economic rights; iii) it addresses an uncharted but rapidly growing response to datafication in civil society; iv) it breaks down disciplinary boundaries in understandings of technology, power, politics and social change; and v) it pursues a combination of engaged research and socio-technical modes of investigation.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["759903"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN", "LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN"], "EU_Contribution": ["EUR 1 498 187,50"], "Project_Title": ["Perovskite Nanocrystal-Nanoreactors for Enhanced Light Emission"], "Total_Cost": ["EUR 1 498 187,50"], "Country": ["Germany", "Germany"], "Project_ACR": ["PINNACLE"], "Technology_Description": "The unprecedented advancement of halide perovskite photovoltaics and light-emission applications has far outpaced the basic scientific research necessary to understand this fascinating yet perplexing material and to optimize material quality and device integration. Additionally, the intricate nature of the perovskite is susceptible to degradation from environmental stress, such as moisture and heat, currently deterring commercialization.", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["759744"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES"], "EU_Contribution": ["EUR 149 645"], "Project_Title": ["MAmmary chemoresistant Tumor deAth by Directed cell ORientation"], "Total_Cost": ["EUR 149 645"], "Country": ["France", "France"], "Project_ACR": ["MATADOR"], "Technology_Description": "Breast cancer is the most common cancer in women worldwide, with nearly 1.7 million new cases diagnosed in 2012. Fortunately, the availability of diagnosis tools to detect mammary neoplastic tissues, as well as transcriptomic biomarkers helping for prognosis, and the diversity of treatment options for primary tumors allows a 90% 5-year survival rate. However the metastatic grade of breast cancer is still not curable.", "To": ["2019-05-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-06-01"], "Project_ID": ["780458"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE", "LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE"], "EU_Contribution": ["EUR 1 313 103"], "Project_Title": ["Firm Growth and Market Power in the Global Economy"], "Total_Cost": ["EUR 1 313 103"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["BIGlobal"], "Technology_Description": "According to the European Commission, to design effective policies for ensuring a \u201cmore dynamic, innovative and competitive\u201d economy, it is essential to understand the decision-making process of firms as they differ a lot in terms of their capacities and policy responses (EC 2007). The objective of my future research is to provide such an analysis. BIGlobal will examine the sources of firm growth and market power to provide new insights into welfare and policy in a globalized world.", "To": ["2022-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["760037"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["DEUTSCHES ZENTRUM FUR NEURODEGENERATIVE ERKRANKUNGEN EV", "DEUTSCHES ZENTRUM FUR NEURODEGENERATIVE ERKRANKUNGEN EV"], "EU_Contribution": ["EUR 148 403"], "Project_Title": ["Redefining Virtual Reality Therapy for Anxiety Disorders"], "Total_Cost": ["EUR 148 403"], "Country": ["Germany", "Germany"], "Project_ACR": ["NEOMENTO"], "Technology_Description": "Social anxiety disorder (SAD) \u2013 the most common type of anxiety disorders \u2013 has severe emotional, financial and social consequences for patients, their families and their social network. Affecting about 7% of Europeans at some point in their life, SAD produces substantial societal cost due to long lasting treatments and extensive periods of reduced working capacity. To address this important problem, the project will establish an innovative system for treating SAD by exploiting the proven therapeutic potential of advanced Virtual Reality (VR) technology.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-12-01"], "Project_ID": ["780453"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["UNIVERSIDADE NOVA DE LISBOA", "UNIVERSIDADE NOVA DE LISBOA", "INSTITUTO DE BIOLOGIA EXPERIMENTAL E TECNOLOGICA"], "EU_Contribution": ["EUR 1 697 493"], "Project_Title": ["Metabolic and Timed Control of Stem Cell Fate in the Developing Animal"], "Total_Cost": ["EUR 1 697 493"], "Country": ["Portugal", "Portugal", "Portugal"], "Project_ACR": ["StemCellHabitat"], "Technology_Description": "Stem cell (SC) proliferation during development requires tight spatial and temporal regulation to ensure correct cell number and right cell types are formed at the proper positions. Currently very little is known about how SCs are regulated during development. Specifically, it is unclear how SC waves of proliferation are regulated and how the fate of their progeny changes during development. In addition, it has recently become evident that metabolism provides additional complexity in cell fate regulation, highlighting the need for integrating metabolic information across physiological levels.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Portugal"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2018-02-01"], "Project_ID": ["759853"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UPPSALA UNIVERSITET", "UPPSALA UNIVERSITET"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["The African Neolithic: A genetic perspective"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["AfricanNeo"], "Technology_Description": "The spread of farming practices in various parts of the world had a marked influence on how humans live today and how we are distributed around the globe. Around 10,000 years ago, warmer conditions lead to population increases, coinciding with the invention of farming in several places around the world. Archaeological evidence attest to the spread of these practices to neighboring regions. In many cases this lead to whole continents being converted from hunter-gatherer to farming societies. It is however difficult to see from archaeological records if only the farming culture spread to other places or whether the farming people themselves migrated. Investigating patterns of genetic variation for farming populations and for remaining hunter-gatherer groups can help to resolve questions on population movements co-occurring with the spread of farming practices. It can further shed light on the routes of migration and dates when migrants arrived.", "To": ["2022-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["759933"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITY OF GLASGOW", "UNIVERSITY OF GLASGOW"], "EU_Contribution": ["EUR 1 239 435"], "Project_Title": ["Categorified Donaldson-Thomas Theory"], "Total_Cost": ["EUR 1 239 435"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["CatDT"], "Technology_Description": "According to string theory, coherent sheaves on three-dimensional Calabi-Yau spaces encode fundamental properties of the universe. On the other hand, they have a purely mathematical definition. We will develop and use the new field of categorified Donaldson-Thomas (DT) theory, which counts these objects. Via the powerful perspective of noncommutative algebraic geometry, this theory has found application in recent years in a wide variety of contexts, far from classical algebraic geometry.", "To": ["2022-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["759967"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 770 375"], "Project_Title": ["Regulatory genomics during Drosophila embryogenesis: dissecting enhancer-promoter interactions"], "Total_Cost": ["EUR 1 770 375"], "Country": ["France", "France"], "Project_ACR": ["Enhancer3D"], "Technology_Description": "In eukaryotes, the complex regulation of temporal- and tissue-specific gene expression is controlled by the binding of transcription factors to enhancers, which in turn interact with the promoter of their target gene(s) via the formation of a chromatin loop. Despite their importance, the properties governing enhancer function and enhancer-promoter loops in the context of the three-dimensional organisation of the genome are still poorly understood.", "To": ["2023-04-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-05-01"], "Project_ID": ["759708"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II.", "UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II."], "EU_Contribution": ["EUR 1 481 813"], "Project_Title": ["Disasters, Communication and Politics in South-Western Europe: the Making of Emergency Response Policies in the Early Modern Age"], "Total_Cost": ["EUR 1 481 813"], "Country": ["Italy", "Italy"], "Project_ACR": ["DISCOMPOSE"], "Technology_Description": "The connections between the circulation of news of extreme events, the making of influential narratives of collective traumas and the development of emergency response policies lie at the heart of this research proposal, which focuses on four Southern European areas: Catalonia, Naples, Sicily and Valencia, from the 16th to the 18th century. How did accounts and individual memories of extreme events amount to authoritative interpretations? In which ways, and to what extent, did the latter orient collective behaviours and the recovery process, in both the short and the long term?", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["759829"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["RIJKSUNIVERSITEIT GRONINGEN", "RIJKSUNIVERSITEIT GRONINGEN"], "EU_Contribution": ["EUR 1 480 708"], "Project_Title": ["The Rules of Interpretation of Customary International Law"], "Total_Cost": ["EUR 1 480 708"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["TRICI-Law"], "Technology_Description": "This ERC proposal revolves around the rules of interpretation of customary international law (CIL). CIL along with treaties are the rules most often used in international law. However, whereas rules of interpretation of treaties have been enshrined in Articles 31-33 of the Vienna Convention on the Law of Treaties (VCLT), the rules of interpretation of CIL have not been the subject of critical study. This gap becomes even more pronounced if we consider that interpretation plays a key role in every judicial case, and that one of the basic markers of effectiveness of any legal system is its predictability. By not knowing the rules that govern the interpretation of CIL, we end up playing a \u2018game\u2019 the rules of which are unknown, and by consequence predictability is far from guaranteed.", "To": ["2023-04-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-05-01"], "Project_ID": ["759728"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["FORSCHUNGSINSTITUT FUR MOLEKULARE PATHOLOGIE GESELLSCHAFT MBH", "FORSCHUNGSINSTITUT FUR MOLEKULARE PATHOLOGIE GESELLSCHAFT MBH"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Rational combination therapies for metastatic cancer"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Austria", "Austria"], "Project_ACR": ["CombaTCancer"], "Technology_Description": "Targeted therapy (TT) is frequently used to treat metastatic cancer. Although TT can achieve effective tumor control for several months, durable treatment responses are rare, due to emergence of aggressive, drug-resistant clones (RCs) with high metastatic competence. Tumor heterogeneity and plasticity result in multifaceted resistance mechanisms and targeting RCs poses a daunting challenge. ", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Austria"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-03-01"], "Project_ID": ["759590"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["DEUTSCHES KREBSFORSCHUNGSZENTRUM", "DEUTSCHES KREBSFORSCHUNGSZENTRUM"], "EU_Contribution": ["EUR 1 499 375"], "Project_Title": ["Exploring cell interactions in the tumor microenvironment with dual ribosome profiling"], "Total_Cost": ["EUR 1 499 375"], "Country": ["Germany", "Germany"], "Project_ACR": ["DualRP"], "Technology_Description": "Cancers develop in very heterogeneous tissue environments. They depend on the tumor microenvironment (TME) for sustained growth, metastasis, and therapy resistance. Stromal cells are genetically stable and they have less likelihood to develop resistance than cancer cells. Therefore, targeting the TME represents an attractive approach for treating cancer. In order to develop new therapeutic strategies to reprogram the TME and inhibit tumor growth and resistance, it is essential to understand in detail the molecular mechanisms of the interactions between cancer and stromal cell populations. However, current methods to study these interactions require complete dissociation of the tumor, exposing the cells to severe stress and affecting dramatically gene expression patterns. Here, I propose to use Dual Ribosome Profiling (DualRP), a system that I recently developed, to study cell interactions in the TME. DualRP is an approach that allows not only simultaneous analysis of gene expression in two interacting cell populations in vivo, but also is able to uncover metabolic limitations in tumors. I aim to apply DualRP to mouse xenograft models where cancer cells interact with non-transformed fibroblasts and I\u2019ll explore the combined response of both populations to cancer therapy. Moreover, I\u2019ll utilize mouse genetic models tailored for DualRP to study cancer cell and macrophages/endothelial cells interactions. I will employ a combination of mouse genetic models, biochemical tools, deep sequencing, and bioinformatics. These studies will provide insight into how gene expression and metabolic programs define the interaction between cancer and stromal cells to promote tumor growth and metastasis, identify potential targets for therapeutic intervention, and provide maps of cell interactions in vivo. Therefore, this research has the potential to significantly advance our understanding of the molecular and metabolic mechanisms underlying the complex cell interactions in the TME.", "To": ["2023-04-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-05-01"], "Project_ID": ["759579"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 149 852"], "Project_Title": ["Innovative testing of microRNA from liquid biopsies using bistable molecular circuits"], "Total_Cost": ["EUR 149 852"], "Country": ["France", "France"], "Project_ACR": ["DeepMiR"], "Technology_Description": "We are designing molecular networks - based on DNA programing- to detect extremely dilute molecular signals and robustly separate them from background noise. This could have relevant applications in the field of molecular diagnostics, in particular in the area of ultra-sensitive testing of nucleic acids from liquid biopsy for example for the detection of circulating microRNA. MicroRNA are difficult targets for standard ultra sensitive techniques such as quantitative PCR, but, because of their presence in the blood stream, they also represent an emerging class of important biomarkers for a wide range of diseases, including cancer. ", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-12-01"], "Project_ID": ["780519"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI TRENTO", "UNIVERSITA DEGLI STUDI DI TRENTO", "FONDAZIONE TOSCANA LIFE SCIENCES"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Engineered bacterial Outer Membrane Vesicles (OMVs) for colorectal cancer immunotherapy"], "Total_Cost": ["EUR 150 000"], "Country": ["Italy", "Italy", "Italy"], "Project_ACR": ["OMVCRC"], "Technology_Description": "This proposal originates from recent results obtained in the course of the Advanced ERC Project \u201cOMVac\u201d, the scope of which is to exploit the unique adjuvanticity properties of bacterial Outer Membrane Vesicles (OMVs) for developing innovative vaccines against infectious diseases and cancer. In particular, Synthetic Biology was applied to engineer OMVs with FAT1, a tumour associated antigen expressed in most primary and metastatic colorectal cancers (CRC). Using cancer models in immunocompetent mice, immunization with FAT1-decorated OMVs inhibited subcutaneous growth of FAT1-positive CT26 cancer cells and protection correlated with an increase in tumour infiltration of CD4+/CD8+ T cells and concomitant decrease of Treg and MDSCs. These promising results prompted the submission of the present proposal which has as main objectives: 1) the demonstration that FAT1-OMV immunization can synergise with the protective activity of checkpoint inhibitors, and 2) the development of a scalable FAT1-OMV production and purification process which could allow testing FAT1-OMV/checkpoint inhibitor combination in the clinical setting.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["780417"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["FONDATION POUR L INSTITUT DE HAUTES ETUDES INTERNATIONALES ET DU DEVELOPPEMENT", "FONDATION POUR L INSTITUT DE HAUTES ETUDES INTERNATIONALES ET DU DEVELOPPEMENT"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Returning to a Better Place: The (Re)assessment of the \u2018Good Life\u2019 in Times of Crisis"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["BETLIV"], "Technology_Description": "What makes for a valuable and good life is a question that many people in the contemporary world ask themselves, yet it is one that social science research has seldom addressed. Only recently have scholars started undertaking inductive comparative research on different notions of the \u2018good life\u2019, highlighting socio-cultural variations and calling for a better understanding of the different imaginaries, aspirations and values that guide people in their quest for better living conditions. Research is still lacking, however, on how people themselves evaluate, compare, and put into perspective different visions of good living and their socio-cultural anchorage. This project addresses such questions from an anthropological perspective, proposing an innovative study of how ideals of the good life are articulated, (re)assessed, and related to specific places and contexts as a result of the experience of crisis and migration. The case studies chosen to operationalize these lines of enquiry focus on the phenomenon of return migration, and consist in an analysis of the imaginaries and experience of return by Ecuadorian and Cuban men and women who migrated to Spain, are dissatisfied with their life there, and envisage/carry out the project of going back to their countries of origin (Ecuador and Cuba respectively). The project\u2019s ambition is to bring together and contribute to three main scholarly areas of enquiry: 1) the study of morality, ethics and what counts as \u2018good life\u2019, 2) the study of the field of economic practice, its definition, value regimes, and \u2018crises\u2019, and 3) the study of migratory aspirations, projects, and trajectories. A multi-sited endeavour, the research is designed in three subprojects carried out in Spain (PhD student), Ecuador (Post-Doc), and Cuba (PI), in which ethnographic methods will be used to provide the first empirically grounded study of the links between notions and experiences of crisis, return migration, and the (re)assessment of good living.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["759649"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITAETSKLINIKUM HEIDELBERG", "UNIVERSITAETSKLINIKUM HEIDELBERG"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Dry season P. falciparum reservoir"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["DrySeasonPf"], "Technology_Description": "The mosquito-borne Plasmodium falciparum parasite is responsible for over 200 million malaria cases and nearly half a million deaths each year among African children. Dependent on Anopheles mosquito for transmission, the parasite faces a challenge during the dry season in the regions where rain seasonality limits vector availability for several months. While malaria cases are restricted to the wet season, clinically silent P. falciparum infections can persist through the dry season and are an important reservoir for transmission. Our preliminary data provides unequivocal evidence that P. falciparum modulates its transcription during the dry season, while the host immune response seems to be minimally affected, suggesting that the parasite has the ability to adapt to a vector-free environment for long periods of time. Understanding the mechanisms which allow the parasite to remain undetectable in absence of mosquito vector, and to restart transmission in the ensuing rainy season will reveal complex interactions between P. falciparum and its host. To that end I propose to: (i) Identify the Plasmodium signalling pathway(s) and metabolic profile associated with long-term maintenance of low parasitaemias during the dry season, (ii) Determine which PfEMP1 are expressed by parasites during the dry season and how effectively they are detected by the immune system, and (iii) Investigate the kinetics of P. falciparum gametocytogenesis, its ability to transmit during the dry season, and uncover sensing molecules and mechanisms of the disappearance and return of the mosquito vector Undoubtedly, results arising from the present multidisciplinary proposal will provide novel insights into the cell biology of dry season P. falciparum parasites, will increase our understanding of their interactions with their hosts and environment. Furthermore, it may benefit the international development agenda goals to design public health strategies to fight malaria.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["759534"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES"], "EU_Contribution": ["EUR 1 998 423"], "Project_Title": ["Long-range coupling of hole spins on a silicon chip"], "Total_Cost": ["EUR 1 998 423"], "Country": ["France", "France"], "Project_ACR": ["LONGSPIN"], "Technology_Description": "With the miniaturization of electronic devices, the semiconductor industry has to deal with complex technical barriers and is forced to introduce novel and innovative concepts. The project proposal is exactly in line with this new paradigm as it proposes to divert CMOS technology to explore a new path for quantum spintronics. Concretely the project aims at using spin-orbit interaction present in the valence band of silicon to drive ultra-fast and ultra-coherent hole spin quantum bits (qubits). The proposal builds on the first demonstration by the principal investigator of a hole spin qubit electrically driven in silicon.", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-03-01"], "Project_ID": ["759388"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["ALBERT-LUDWIGS-UNIVERSITAET FREIBURG", "ALBERT-LUDWIGS-UNIVERSITAET FREIBURG"], "EU_Contribution": ["EUR 1 488 750"], "Project_Title": ["Supercapacitive Polymer Electrodes for Directing Epithelial Repair"], "Total_Cost": ["EUR 1 488 750"], "Country": ["Germany", "Germany"], "Project_ACR": ["SPEEDER"], "Technology_Description": "In this project we develop a new approach, using the conducting polymer poly (3,4-ethylene dioxythiophene) (PEDOT) to apply electrical fields (EFs) for guidance of cells. EFs are recognised as important guidance cues in the development and life cycle of human tissues. However, better tools are urgently needed to support experiments and applications. By developing supercapacitive PEDOT electrodes, able to support an ionic flow over extended time frames, we here target the most widely studied clinical application for EF stimulation, accelerated wound healing. Our technology facilitates the transfer from petri dish to device by offering an alternative driving process to metals. In addition, we establish a strategy where electrodes can be recharged in situ, by using intermediate periods of current flow in the reverse direction and below the threshold for triggering a biological response. Ionic flow driven by PEDOT electrodes can, in contrast to metals, be reversed with any small ion present in the electrolyte.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["759655"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["VYSOKE UCENI TECHNICKE V BRNE", "VYSOKE UCENI TECHNICKE V BRNE"], "EU_Contribution": ["EUR 1 377 495"], "Project_Title": ["Towards the Understanding a Metal-Tumour-Metabolism"], "Total_Cost": ["EUR 1 377 495"], "Country": ["Czech Republic", "Czech Republic"], "Project_ACR": ["ToMeTuM"], "Technology_Description": "A tumour cell uses both genetic and protein weapons in its development. Gaining a greater understanding of these lethal mechanisms is a key step towards developing novel and more effective treatments. Because the metal ion metabolism of a tumour cell is not fully understood, we will address the challenge of explaining the mechanisms of how a tumour cell copes both with essential metal ions and platinum based drugs. The metal-based mechanisms help a tumour to grow on one side and to protect itself against commonly used metal-based drugs. On the other side, the exact description of these mechanisms, which are being associated with multi-drug resistance occurrence and failure of a treatment, still remains unclear. We will reveal the mechanism of the as yet not understood biochemical and molecularly-biological relationships and correlations between metal ions and proteins in a tumour development revealing the way how to suppress the growth and development of a tumour and to markedly enhance the effectiveness of a treatment. ", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Czech Republic"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["759585"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM", "UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 1 499 631"], "Project_Title": ["The Disrupted Society: mapping the societal effects of blockchain technology diffusion"], "Total_Cost": ["EUR 1 499 631"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["BLOCKCHAINSOCIETY"], "Technology_Description": "Recent advances in cryptography yielded the blockchain technology, which enables a radically new and decentralized method to maintain authoritative records, without the need of trusted intermediaries. Bitcoin, a cryptocurrency blockchain application has already demonstrated that it is possible to operate a purely cryptography-based, global, distributed, decentralized, anonymous financial network, independent from central and commercial banks, regulators and the state.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["759681"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSITAET LEIPZIG", "THE UNIVERSITY OF BIRMINGHAM"], "EU_Contribution": ["EUR 1 497 168"], "Project_Title": ["Hausa and Kanuri languages as archive for the history of Sahara and Sahel in 18th and 19th century"], "Total_Cost": ["EUR 1 497 168"], "Country": ["France", "France", "Germany", "United Kingdom"], "Project_ACR": ["LANGARCHIV"], "Technology_Description": "The eighteenth and nineteenth century history of the central Sahara and Sahel has primarily been written using European or jihadist Arabic sources. This has led to an overwhelming emphasis on religion, politics, and geography as core themes that shaped social and cultural dynamics in this region. By focusing on sources in African languages\u2014until now largely forgotten by historians\u2014the project LANGARCHIV aims to enrich and expand this narrative. Hausa and Kanuri material collected by Germanophone, British, and French scholars for linguistic study between 1772 and 1913 in West and North Africa, England, and Brazil cries out for collaboration between historians, linguists, and anthropologists. This rich body of primary sources remains under-studied, having been rejected as colonial even though the majority were collected before colonial occupation. A general reconsideration of this material will enable a major shift in our understanding, toward a \u2018history from below\u2019 that will make it possible to explore the history of Sahelian societies through the stories that Sahelians told about themselves. Serving as linguae francae, in the eighteenth and nineteenth centuries Hausa and Kanuri were spoken from Tripoli to Kano and Bahia, and today Hausa remains the most widely spoken language in West Africa, with 50 million speakers scattered over more than 6 countries LANGARCHIV will be the first project to explore materials in African languages as sources for African history. Combining an epistemological analysis of European scientific interest in African languages with the will to write a social history that overcomes the jihadist bias, the project aims to bring about a paradigmatic shift in the history of the central Sahara and Sahel. It will achieve this goal by revealing a rich body of primary sources and by developing an innovative analytical framework for using documents generated by early students of African languages and cultures as historical sources.", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["759390"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["LANCASTER UNIVERSITY", "LANCASTER UNIVERSITY"], "EU_Contribution": ["EUR 1 493 605"], "Project_Title": ["Hidden Hunger, Forgotten Food"], "Total_Cost": ["EUR 1 493 605"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["FAIRFISH"], "Technology_Description": "Food Security is a grand challenge of our time, but three factors inhibit our ability to meet global targets. First, interdisciplinary approaches incorporating ecological, social, and health sciences are fundamental, but lacking. Second, a disproportionate focus on food quantity overlooks \u2018hidden hunger\u2019, or micronutrient deficiencies, which are implicated in over a million deaths annually. Third, small-scale fisheries (SSF) reach 100s of millions of people in the developing world, hold potential for achieving food security, but remain \u2018forgotten food\u2019 in global discourse. Consequently, an interdisciplinary approach that tackles hidden hunger within SSF is a critical frontier for food security research.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["759457"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM", "THE UNIVERSITY OF BIRMINGHAM"], "EU_Contribution": ["EUR 1 466 014"], "Project_Title": ["Spatio-Temporal Attention and Representation Tracking: the precise neural architecture of conscious object perception"], "Total_Cost": ["EUR 1 466 014"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["START"], "Technology_Description": "The ability to consciously recognise faces, objects, or sounds is crucial for adaptive behaviour and survival. Yet, how our conscious experience of the world emerges in our brain remains unknown. The overall aim of the START programme is to fill an important gap in our understanding of consciousness by elucidating the neural underpinnings of conscious access. How does the brain select relevant information among distractors, and keep this information in mind? Why does our ability to consciously recognise salient objects sometimes fail under pressure and exhibit variability across days and individuals? Current theories of conscious access thus far rely on EEG recordings or fMRI measurements, which in isolation offer limited insights into the precise neural dynamics of conscious access. A further shortcoming of current models is their limited explanations for inter-trial and inter-individual variations in conscious access thresholds. START will tackle these challenges using attentional blink tasks involving the perception and recollection of visual objects. First, it will precisely track where in the brain and when in time the representations critical for conscious access are established, by using a novel approach which combines the strengths of EEG, fMRI, and Deep Convolutional Neuronal Networks. Second, START will reveal how activity patterns are amplified by the brain and encoded in working memory using multivariate pattern analyses of EEG data and novel experimental designs. Finally, START will carefully model variability in task performance across trials and participants using a new approach of representational sampling. In summary, START will provide new insights on the precise spatio-temporal dynamics of conscious access, the mechanisms governing it, and the idiosyncratic subtleties behind the meanderings of consciousness. This has deep implications for our understandings of brain health and disease, especially in clinical cases where consciousness is impaired.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["759432"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["STICHTING KATHOLIEKE UNIVERSITEIT BRABANT", "STICHTING KATHOLIEKE UNIVERSITEIT BRABANT"], "EU_Contribution": ["EUR 1 496 944"], "Project_Title": ["Belief Systems Project"], "Total_Cost": ["EUR 1 496 944"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["BSP"], "Technology_Description": "Belief systems research is vital for understanding democratic politics, extremism, and political decision-making. What is the basic structure of belief systems? Clear answers to this fundamental question are not forthcoming. This is due to flaws in the conceptualization of belief systems. The state-of-the-art treats a belief system as a theoretical latent variable that causes people\u2019s responses on attitudes and values relevant to the belief system. This approach cannot assess a belief system because it cannot assess the network of connections between the beliefs\u2013attitudes and values\u2013that make up the system; it collapses across them and the interrelationships are lost. ", "To": ["2023-06-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-07-01"], "Project_ID": ["759320"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM", "THE UNIVERSITY OF BIRMINGHAM"], "EU_Contribution": ["EUR 1 498 982"], "Project_Title": ["GLOBAL LITERARY THEORY"], "Total_Cost": ["EUR 1 498 982"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["GlobalLIT"], "Technology_Description": "Literary theory is often regarded as a twentieth century invention, with no precedents prior to modernity. This relegates older discourses on literature to the status of source material, pertaining to literature\u2019s past, rather than as springboards for literature\u2019s future. While the self-understanding of literary theory\u2019s modernity helped to bring about the discipline\u2019s birth, and hence was innovative in its own time, at present it accounts for many gaps and limits within its current structure, whereby European aesthetic categories remain normative and lesser-known geographies are marginalized within synthetic accounts of literary form. Even when the literatures studied are non-European, the literary theory used to understand these texts often circulates within a restricted set of modern European traditions.", "To": ["2023-04-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-05-01"], "Project_ID": ["759346"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["DEUTSCHES HERZZENTRUM MUNCHEN", "DEUTSCHES HERZZENTRUM MUNCHEN"], "EU_Contribution": ["EUR 1 477 680"], "Project_Title": ["Stress as a modifier of atherosclerosis - Novel mechanistic insights and therapeutic avenues -"], "Total_Cost": ["EUR 1 477 680"], "Country": ["Germany", "Germany"], "Project_ACR": ["STRATO"], "Technology_Description": "Atherosclerosis and its complications such as acute coronary syndromes (myocardial infarction and unstable angina) are leading causes of death in the EU and worldwide. Mental stress is known to be a major trigger for the onset of acute coronary syndromes, even in patients with state-of-the-art medical treatment. How acute mental stress rapidly drives plaque destabilization causing acute coronary syndromes is poorly understood and consequently specific treatment, although urgently needed, is lacking. Mental stress is known to affect the immune system. Leukocytes, the effector cells of the immune system, are main instigators not only of plaque progression, but also of plaque destabilization. We hypothesize that acute mental stress rapidly aggravates plaque inflammation, which renders plaques more vulnerable and prone to rupture.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2018-02-01"], "Project_ID": ["759272"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITE JEAN MONNET SAINT-ETIENNE", "UNIVERSITE JEAN MONNET SAINT-ETIENNE"], "EU_Contribution": ["EUR 1 060 250"], "Project_Title": ["Micro-pyrites associated with organic material in ancient stromatolites: a new proxy attesting for their biogenicity"], "Total_Cost": ["EUR 1 060 250"], "Country": ["France", "France"], "Project_ACR": ["STROMATA"], "Technology_Description": "Identifying Archean fossil remains from the Earth\u2019s early biosphere is ambitious and determining the biological origin and the associated metabolic pathways present in these fossils is one outstanding question in the bigger quest of how life evolved on Earth. Stromatolites and Microbially Induced Sedimentary Structures (MISS) are considered as one of the earliest evidence of Life in Earth\u2019s history, and can be found from the Archean to the present time. Stromatolites are \u201cattached laminated, sedimentary growth structure accretionary away from a point of initiation\u201d, and their morphological comparison with actual structure prevail for assessing the microbial origin of ancient stromatolite in the geological record. However, experimental studies have shown that abiotic precipitation can also form structures with a similar morphology. Therefore stable isotope proxies have been used to identify past microbial metabolisms even if abiotic processes can also produce similar isotope composition. Therefore new biogenicity criteria are needed to be determined by studying modern and ancient stromatolites and by comparing them to abiotic experiment. Stromatolites and MISS contain submicrometer sulfides (pyrite) that can have recorded large isotopic variations, interpreted as reflecting the influence of various microbial metabolisms like microbial sulfate reduction and iron respiration. STROMATA proposes to define new criteria based on actual stromatolite and to test the earliest traces of life by studying in situ these nano-pyrites in various emblematic and well-characterized samples from the Archean. STROMATA will be the first far-reaching scientific in situ study of nano-pyrite in ancient (3.4 to 1.9 Ga) and modern microbial mats and stromatolites and will compare the results with experimentally produced abiotic pyrite. Due to the small scale of the pyrite, STROMATA will develop an original in situ approach by combining state of art techniques, SIMS, NanoSIMS, FEG-TEM, XANES.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["759289"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["HITS GGMBH", "HITS GGMBH"], "EU_Contribution": ["EUR 1 499 485"], "Project_Title": ["General Relativistic Moving-Mesh Simulations of Neutron-Star Mergers"], "Total_Cost": ["EUR 1 499 485"], "Country": ["Germany", "Germany"], "Project_ACR": ["GreatMoves"], "Technology_Description": "In the arising era of gravitational-wave (GW) astronomy the demand for the next-generation of neutron-star (NS) merger models has never been so great. By developing the first relativistic moving-mesh simulations of NS mergers, we will be able to reliably link observables of these spectacular events to fundamental questions of physics. Our approach will allow us to maximize the information that can be obtained from different GW oscillations of the postmerger remnant. In this way we will demonstrate the scientific potential of future postmerger GW detections to unravel unknown properties of NSs and high-density matter. Based on our models we will work out the optimal GW data analysis strategy towards this goal.", "To": ["2023-04-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-05-01"], "Project_ID": ["759253"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE", "INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE"], "EU_Contribution": ["EUR 1 499 793,77"], "Project_Title": ["Molecular mechanisms of interferon-induced antiviral restriction and signalling"], "Total_Cost": ["EUR 1 499 793,77"], "Country": ["France", "France"], "Project_ACR": ["ANTIViR"], "Technology_Description": "Interferons (IFNs), which are signalling proteins produced by infected cells, are the first line of defence against viral infections. IFNs induce, in infected and neighbouring cells, the expression of hundreds of IFN-stimulated genes (ISGs). The ISGs in turn induce in cells a potent antiviral state, capable of preventing replication of most viruses, including Human Immunodeficiency Virus type 1 (HIV-1) and influenza A virus (FLUAV). Identifying the antiviral ISGs and understanding their mechanisms of action is therefore crucial to progress in the fight against viruses. ", "To": ["2022-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-12-01"], "Project_ID": ["759226"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITY OF NEWCASTLE UPON TYNE", "UNIVERSITY OF NEWCASTLE UPON TYNE"], "EU_Contribution": ["EUR 1 499 250"], "Project_Title": ["Endothelial RNA Modifications in Vascular Homeostasis and Disease"], "Total_Cost": ["EUR 1 499 250"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["MODVASC"], "Technology_Description": "Endothelial cells cover the entire arterial and venous tree, and play a pivotal role in vascular and organ homeostasis. In general, cardiovascular risk factors induce endothelial cell activation towards a pro-inflammatory phenotype leading to atherosclerosis, a major cause of mortality in the Western world. Understanding the mechanisms that orchestrate endothelial cell functions and response to environmental stimuli is essential for the discovery and development of novel biomarkers and therapeutic strategies in vascular disease. ", "To": ["2023-05-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-06-01"], "Project_ID": ["759248"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 1 499 616"], "Project_Title": ["Bringing into focus the cellular dynamics of the plant growth hormone gibberellin"], "Total_Cost": ["EUR 1 499 616"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["CELL HORMONE"], "Technology_Description": "During an organism\u2019s development it must integrate internal and external information. An example in plants, whose development stretches across their lifetime, is the coordination between environmental stimuli and endogenous cues on regulating the key hormone gibberellin (GA). The present challenge is to understand how these diverse signals influence GA levels and how GA signalling leads to diverse GA responses. This challenge is deepened by a fundamental problem in hormone research: the specific responses directed by a given hormone often depend on the cell-type, timing, and amount of hormone accumulation, but hormone concentrations are most often assessed at the organism or tissue level. Our approach, based on a novel optogenetic biosensor, GA Perception Sensor 1 (GPS1), brings the goal of high-resolution quantification of GA in vivo within reach. In plants expressing GPS1, we observe gradients of GA in elongating root and shoot tissues. We now aim to understand how a series of independently tunable enzymatic and transport activities combine to articulate the GA gradients that we observe. We further aim to discover the mechanisms by which endogenous and environmental signals regulate these GA enzymes and transporters. Finally, we aim to understand how one of these signals, light, regulates GA patterns to influence dynamic cell growth and organ behavior. Our overarching goal is a systems level understanding of the signal integration upstream and growth programming downstream of GA. The groundbreaking aspect of this proposal is our focus at the cellular level, and we are uniquely positioned to carry out our multidisciplinary aims involving biosensor engineering, innovative imaging, and multiscale modelling. We anticipate that the discoveries stemming from this project will provide the detailed understanding necessary to make strategic interventions into GA dynamic patterning in crop plants for specific improvements in growth, development, and environmental responses.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["759282"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE", "INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE"], "EU_Contribution": ["EUR 1 787 400"], "Project_Title": ["Structural differences in mRNA translation machineries between eukaryotic pathogens and their mammalian hosts"], "Total_Cost": ["EUR 1 787 400"], "Country": ["France", "France"], "Project_ACR": ["transtryp"], "Technology_Description": "mRNA translation consists on translating the genetic code to proteins by the ribosome that is universally conserved in all cells. However, its structure presents significant differences between bacteria and eukaryotes. Partly because of these differences, the bacterial ribosome can be targeted specifically by a number of antibiotics without affecting the eukaryotic host cells. However, the conservation of the ribosome among eukaryotes complicates the search for specific drugs against eukaryotic pathogens such as certain protozoa like plasmodium and kinetoplastids.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["759120"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSIDAD COMPLUTENSE DE MADRID", "UNIVERSIDAD COMPLUTENSE DE MADRID"], "EU_Contribution": ["EUR 1 498 855"], "Project_Title": ["Decentralized Blockchain-based Organizations for Bootstrapping the Collaborative Economy"], "Total_Cost": ["EUR 1 498 855"], "Country": ["Spain", "Spain"], "Project_ACR": ["P2PMODELS"], "Technology_Description": "The Collaborative Economy (CE) is rapidly expanding through new forms of Internet labor and commerce, from Wikipedia to Kickstarter and Airbnb. However, it suffers from 3 main challenges: (1) Infrastructure: centralized surveillance that the central hubs of information exercise over their users, (2) Governance: disempowered communities which do not have any decision-making influence over the platform, and (3) Economy: concentration of profits in a few major players who do not proportionally redistribute them to the contributors.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["759207"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["DEUTSCHE DIABETES FORSCHUNGSGESELLSCHAFT EV", "DEUTSCHE DIABETES FORSCHUNGSGESELLSCHAFT EV"], "EU_Contribution": ["EUR 1 492 313,75"], "Project_Title": ["Ceramide Synthases in Diabetic Beta Cell Demise"], "Total_Cost": ["EUR 1 492 313,75"], "Country": ["Germany", "Germany"], "Project_ACR": ["CESYDE"], "Technology_Description": "Sphingolipids including ceramides are building blocks of cell membranes, but also act as regulated intracellular messenger molecules. Emerging data indicate that sphingolipids are dynamically regulated by nutrients, and in turn control systemic metabolism, for example, by modulating insulin secretion, proliferation and cell death of pancreatic beta cells. Dysfunction and death of beta cells are key events during the development of diabetes, from which more than 400 million patients suffer worldwide. While pharmacological inhibition of general ceramide biosynthesis is protective against diabetes in animal studies, side effects of total loss of ceramides prevent medical implementation. The de novo synthesis of ceramides is fully dependent on six ceramide synthase enzymes (CerS 1-6), which are expressed in a tissue specific manner, and generate ceramides with different chain lengths. Currently, the functional roles and regulatory modulators of each CerS are unknown in pancreatic beta cells. Importantly, the downstream mechanisms by which ceramides impair beta cell function and eventually cause diabetes are not defined. Here, I propose to combine genomics, proteomics and lipidomics to assess the function of ceramide synthases expressed in mouse and human beta cells. Furthermore, both the subcellular localisation and the post-translational modifications of CerS will be determined. The ceramide-interacting proteins mediating the deleterious effects of ceramides will be identified by lipid-protein crosslinking and functionally tested. Finally, in a translational approach, we will test the ability of recently generated novel specific CerS inhibitors with improved specificity to ameliorate beta cell stress, and improve insulin secretion in mouse and human beta cells. In sum, we will identify, characterize, validate and target ceramide synthases involved in beta cell biology and development of diabetes.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["759099"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 1 376 080"], "Project_Title": ["The Transformation of Post-War Education: Causes and Effects"], "Total_Cost": ["EUR 1 376 080"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["SCHOOLPOL"], "Technology_Description": "The educational context that children are born into dramatically shapes their life chances, affecting not only their future economic well-being but also their propensity to participate in civic and political life. That education matters is hardly a new insight; however, an increasing body of research points to the importance of varying educational contexts on a range of outcomes. Despite these insights, we have little systematic comparative data on the educational contexts in which most the current adult population was actually educated, the political determinants of these contexts, or their long-term impact on a range of social and political outcomes. SCHOOLPOL proposes three innovative and high-reward work streams aimed at filling these lacunae. It will create the first systematic database of a) educational policy from 1945-2015 and b) regional educational performance from 1980-2015 across advanced democracies. Building on insights from both sociological studies of educational choice, economic analyses of geographic sorting, and recent work in political science on educational investment, SCHOOLPOL will reshape our understanding of education politics, showing how broad public objectives (growth, equality) in educational provision interact with the private objectives of organized groups and voters in particular communities to shape different distributions of educational resources and quality. Finally, SCHOOLPOL investigates the consequences of earlier political choices over education on long-term social and economic outcomes, examining the link between varying cohort educational experiences and social mobility and political participation using new and existing surveys. This innovative project breaks new ground in both the study of education and advanced political economies, providing crucial resources to policymakers and academics alike in understanding and crafting school reform.", "To": ["2023-04-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-05-01"], "Project_ID": ["759188"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UPPSALA UNIVERSITET", "UPPSALA UNIVERSITET"], "EU_Contribution": ["EUR 1 491 013"], "Project_Title": ["1D-electrons coupled to dissipation: a novel approach for understanding and engineering superconducting materials and devices"], "Total_Cost": ["EUR 1 491 013"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["1D-Engine"], "Technology_Description": "Correlated electrons are at the forefront of condensed matter theory. Interacting quasi-1D electrons have seen vast progress in analytical and numerical theory, and thus in fundamental understanding and quantitative prediction. Yet, in the 1D limit fluctuations preclude important technological use, particularly of superconductors. In contrast, high-Tc superconductors in 2D/3D are not precluded by fluctuations, but lack a fundamental theory, making prediction and engineering of their properties, a major goal in physics, very difficult. This project aims to combine the advantages of both areas by making major progress in the theory of quasi-1D electrons coupled to an electron bath, in part building on recent breakthroughs (with the PIs extensive involvement) in simulating 1D and 2D electrons with parallelized density matrix renormalization group (pDMRG) numerics. Such theory will fundamentally advance the study of open electron systems, and show how to use 1D materials as elements of new superconducting (SC) devices and materials: 1) It will enable a new state of matter, 1D electrons with true SC order. Fluctuations from the electronic liquid, such as graphene, could also enable nanoscale wires to appear SC at high temperatures. 2) A new approach for the deliberate engineering of a high-Tc superconductor. In 1D, how electrons pair by repulsive interactions is understood and can be predicted. Stabilization by reservoir - formed by a parallel array of many such 1D systems - offers a superconductor for which all factors setting Tc are known and can be optimized. 3) Many existing superconductors with repulsive electron pairing, all presently not understood, can be cast as 1D electrons coupled to a bath. Developing chain-DMFT theory based on pDMRG will allow these materials SC properties to be simulated and understood for the first time. 4) The insights gained will be translated to 2D superconductors to study how they could be enhanced by contact with electronic liquids.", "To": ["2023-09-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-10-01"], "Project_ID": ["758935"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE", "INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE"], "EU_Contribution": ["EUR 1 499 410"], "Project_Title": ["GUIDANCE AND FUNCTION OF REGENERATIVE FIBERS IN ADULT CNS"], "Total_Cost": ["EUR 1 499 410"], "Country": ["France", "France"], "Project_ACR": ["DRIVE"], "Technology_Description": "The impairment of central nervous system (CNS) leads to irreversible loss of vital functions because, unlike young neurons, mature neurons are not able to regenerate. Thus, understanding the detailed mechanisms of axonal growth and repair remains one of the greatest challenges of neurobiology and for society. If the extrinsic factors fail to reach levels required for regeneration, manipulating intrinsic pathways has shown promising results. Particularly, my work demonstrated that the simultaneous activation of mTOR, JAK/STAT and c-myc pathways allows exceptional regeneration with axons close to their targets. However it also exacerbates previously described phenomenon of misguidance with potential aberrant circuit formation. My unique model opens up the possibility to explore these fundamental questions of CNS regeneration. I propose to address the yet unexplored problem of the guidance of regenerating axons in adults in order to promote the formation of a functional new circuit after injury. Indeed what are the modalities of guidance in the adult? Are axons still responsive to developmental guidance cues and are they still expressed? Can regenerative axons form connections with their targets and are these connections functional?", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-03-01"], "Project_ID": ["759089"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 437 188"], "Project_Title": ["Understanding Type Ia SuperNovae for Accurate Cosmology"], "Total_Cost": ["EUR 1 437 188"], "Country": ["France", "France"], "Project_ACR": ["USNAC"], "Technology_Description": "With this proposal I aim at removing astrophysical biases in SN cosmology that limit improvements in the derivation of properties of the dark energy (DE). DE is the cause of the recent acceleration of the expansion of the Universe and accounts for ~70% of its total energy. The initial discovery based on distance measurements from Type Ia Supernovae (SNeIa) has since been confirmed with several independent probes. Today, the goal of cosmology is to understand the nature of DE, and SNeIa remain a central probe for this endeavor. However, the nature of SNeIa remains largely unknown, which limits our ability to accurately trace the properties of the Universe. The proposed research program focuses on solving this problem.", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-03-01"], "Project_ID": ["759194"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["BAYERISCHE JULIUS-MAXIMILIANS UNIVERSITAT WURZBURG", "BAYERISCHE JULIUS-MAXIMILIANS UNIVERSITAT WURZBURG"], "EU_Contribution": ["EUR 1 498 750"], "Project_Title": ["Tissue-resident Lymphocytes: Development and Function in \u201creal-life\u201d Contexts"], "Total_Cost": ["EUR 1 498 750"], "Country": ["Germany", "Germany"], "Project_ACR": ["TissueLymphoContexts"], "Technology_Description": "Most anatomical compartments, including mucosal barrier surfaces, solid organs and vascular spaces host different types of tissue-resident lymphocytes providing local networks for immune surveillance and front-line defense to microbial invasion. In addition to immediate effector functions, tissue-resident lymphocytes orchestrate and regulate inflammatory responses, and contribute to tissue homeostasis, repair and barrier function. Understanding the generation and function of tissue-resident lymphocytes is therefore expected to reveal targets for improving vaccination and immunotherapy. Barrier tissues of free-living mice and men, but not those of laboratory mice kept under specific pathogen free conditions, are continuously exposed to an array of antigenically complex pathogens, microbial symbionts and environmental factors, which dramatically alter the abundance, composition and basal activation state of local pools of tissue-resident cells. Therefore, we propose to study the development, functions and cellular interactions of tissue-resident lymphocytes in experimental models that mirror \u201creal-life\u201d contexts. First, we will investigate how polyclonal pools of tissue-resident memory CD8+ T cells (TRMs) are established during infection with antigenically complex pathogens. Second, we will restore physiologic exposure to specific pathogens and induce alterations of local microbiota in SPF mice, in order to investigate the induction, function and local interactions of tissue-resident lymphocytes in physiologic tissue environments. In addition, we will explore targeted microbial exposure as a \u201evaccination\u201c strategy to induce \u201enon-canonical\u201c tissue-resident cells in the lung in order to improve protection against infections with multi-resistant bacteria representing major clinical problems in hospitalized patients. In summary, we will investigate fundamental mechanisms of tissue immunity and vaccination in contexts relevant for human physiology and disease.", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["759176"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITE DE LAUSANNE", "UNIVERSITE DE LAUSANNE"], "EU_Contribution": ["EUR 1 499 885"], "Project_Title": ["Transcriptional controls over cerebellar neuron differentiation and circuit assembly"], "Total_Cost": ["EUR 1 499 885"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["CERDEV"], "Technology_Description": "The cerebellum is a critical regulator of motor function, which acts to integrate ongoing body states, sensory inputs and desired outcomes to adjust motor output. This motor control is achieved by a relatively small number of neuron types receiving two main sources of inputs and forming a single output pathway, the axons of Purkinje cells. Although the cerebellum is one of the first structures of the brain to differentiate, it undergoes a prolonged differentiation period such that mature cellular and circuit configuration is achieved only late after birth. Despite the functional importance of this structure, the molecular mechanisms that control type-specific cerebellar neurons generation, differentiation, and circuit assembly are poorly understood and are the topic of the present study.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["759112"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 499 922"], "Project_Title": ["Deconstructing pain with predictive models: from neural architecture to pain relief"], "Total_Cost": ["EUR 1 499 922"], "Country": ["Germany", "Germany"], "Project_ACR": ["PredictingPain"], "Technology_Description": "Pain is a burden for millions of people in terms of suffering, as well as for society in terms of costs. While it is well established that the perception of pain is not necessarily related to the amount of sensory input, a mechanistic framework for this is still lacking at the neurobiological level, although it would be of utmost importance for inspiring new therapeutic approaches. In PredictingPain, I will provide such a framework by applying recent insights from computational neuroscience in the form of \u2018predictive coding\u2019 to pain. Predictive coding models assume that perception is an active process in which the brain is not just passively responding to sensory inputs, but is instead constantly generating predictions about its sensory inputs.", "To": ["2023-09-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2018-10-01"], "Project_ID": ["758974"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN", "JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN"], "EU_Contribution": ["EUR 1 416 934"], "Project_Title": ["Predictive Memory Systems Across the Human Lifespan"], "Total_Cost": ["EUR 1 416 934"], "Country": ["Germany", "Germany"], "Project_ACR": ["PIVOTAL"], "Technology_Description": "As neuroscientific findings on brain functions accumulate, it is increasingly important to derive a set of overarching general principles about how the human brain works. For this, the predictive coding framework emerges as a promising route, with the notion that the brain operates as a prediction machine; internal models in the brain predict future states against which incoming information of new experience is compared. ", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["758898"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 1 486 938"], "Project_Title": ["Functional Biointerface Elements via Biomicrofabrication"], "Total_Cost": ["EUR 1 486 938"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["BIOELE"], "Technology_Description": "Imagine in the future, bionic devices that can merge device and biology which can perform molecular sensing, simulate the functions of grown-organs in the lab, or even replace or improve parts of the organ as smart implants? Such bionic devices is set to transform a number of emerging fields, including synthetic biotechnology, regenerative medicine, and human-machine interfaces. Merging biology and man-made devices also mean that materials of vastly different properties need to be seamlessly integrated. One of the promising strategies to manufacture these devices is through 3D printing, which can structure different materials into functional devices, and simultaneously intertwining with biological matters. However, the requirement for biocompatibility, miniaturisation, portability and high performance in bionic devices pushes the current limit for micro- nanoscale 3D printing. ", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["758865"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSIDAD AUTONOMA DE MADRID", "UNIVERSIDAD AUTONOMA DE MADRID"], "EU_Contribution": ["EUR 1 499 719"], "Project_Title": ["4-Colours/2-Junctions of III-V semiconductors on Si to use in electronics devices and solar cells"], "Total_Cost": ["EUR 1 499 719"], "Country": ["Spain", "Spain"], "Project_ACR": ["4SUNS"], "Technology_Description": "It was early predicted by M. Green and coeval colleagues that dividing the solar spectrum into narrow ranges of colours is the most efficient manner to convert solar energy into electrical power. Multijunction solar cells are the current solution to this challenge, which have reached over 30% conversion efficiencies by stacking 3 junctions together. However, the large fabrication costs and time hinders their use in everyday life. It has been shown that highly mismatched alloy (HMA) materials provide a powerful playground to achieve at least 3 different colour absorption regions that enable optimised energy conversion with just one junction. Combining HMA-based junctions with standard Silicon solar cells will rocket solar conversion efficiency at a reduced price. To turn this ambition into marketable devices, several efforts are still needed and few challenges must be overcome.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["758885"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM", "UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 1 499 664"], "Project_Title": ["Politics and Emotions Investigated Comparatively"], "Total_Cost": ["EUR 1 499 664"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["POLEMIC"], "Technology_Description": "Many claim that politicians make more, and more extreme, emotional appeals than ever before, because these appeals win over the emotional citizen. With highly emotive language people like Donald Trump, Geert Wilders or Marine Le Pen are pounding on the portals to power. Do such emotional appeals affect citizens\u2019 political choices? Yes, they can. But, citizens\u2019 existing emotional attachments to parties, leaders or issues moderate the success of emotional appeals. POLEMIC will extend existing theory and use novel methods to explain when (types of) emotional appeals are persuasive, and when emotional attachments prevent persuasion.", "To": ["2023-03-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-04-01"], "Project_ID": ["759079"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["STICHTING KATHOLIEKE UNIVERSITEIT", "STICHTING KATHOLIEKE UNIVERSITEIT"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["New Chemical Tools for Precision Glycotherapy"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["GlycoEdit"], "Technology_Description": "Glycosylation, the expression of carbohydrate structures on proteins and lipids, is found in all the domains of life. The collection of all glycans found on a cell is called the \u201cglycome\u201d which is information rich and a key player in a plethora of physiological and pathological processes. The information that the glycome holds can be written, read and erased by glycosyltransferases, lectins and glycosidases, respectively. The immense structural complexity and the fact that glycan biosynthesis is not under direct genetic control makes it very difficult to study the glycome.", "To": ["2022-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["758913"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITEIT MAASTRICHT", "UNIVERSITEIT MAASTRICHT"], "EU_Contribution": ["EUR 148 530"], "Project_Title": ["Reading the mind\u2019s eye at 7 Tesla - A fMRI-based communication brain-computer interface for severely motor-impaired patients"], "Total_Cost": ["EUR 148 530"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["MindsEyeBCI"], "Technology_Description": "The Advanced ERC project ColumnarCodeCracking has pioneered ultra-high field fMRI at 7 Tesla for sub-millimeter neuroscience applications targeting cortical columns and cortical layers. One sub-project of the ERC project was to explore whether it is possible to build new brain computer interfaces (BCIs) exploiting the strong signal quality and higher resolution achievable at ultra-high magnetic fields. As part of our research (Emmerling et al., 2017, http://cordis.europa.eu/news/rcn/124885_en.html) we discovered that it is possible to reconstruct letter shapes from activity in early visual areas that are merely imagined by participants during 7 Tesla fMRI scanning. Importantly, we could demonstrate that imagined letter shapes can be decoded from single imagination events of about 10 seconds without the need to average across multiple repetitions. These observations stimulated the idea for this PoC application, namely to use letter imagery for the first time as a communication BCI. We also have tested deep learning auto-encoder networks as part of the analysis and observed that these tools substantially increase the robustness of letter reconstruction. The three major goals of this PoC are 1) to perform 7 Tesla fMRI experiments with healthy participants to evaluate whether decoding brain activity patterns during letter imagery can be performed robust enough to be used as a communication BCI for severely motor-impaired (locked-in) patients, 2) to develop a BCI/neurofeedback software performing all required advanced online analyses, and 3) evaluate whether showing the online decoded letter during imagery helps participants to fine-tune the resulting shape. While 7 Tesla fMRI is not yet widely available in clinical settings, we aim to prepare first tests of the developed prototype with locked-in patients.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["779860"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN", "THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN", "UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN"], "EU_Contribution": ["EUR 149 945"], "Project_Title": ["Articular cartilage regeneration through the recruitment of bone marrow derived mesenchymal stem cells into extracelluar matrix derived scaffolds anchored by 3D printed polymeric supports"], "Total_Cost": ["EUR 149 945"], "Country": ["Ireland", "Ireland", "Ireland"], "Project_ACR": ["ANCHOR"], "Technology_Description": "Osteoarthritis (OA), the most common form of arthritis, is a serious disease of the joints affecting nearly 10% of the population worldwide. The onset of OA has been associated with defects to articular cartilage that lines the bones of synovial joints. Current strategies to treat articular cartilage defects are ineffective and/or prohibitively expensive. The aim of ANCHOR is to develop and commercialise a new medicinal product for articular cartilage regeneration that recruits endogenous bone marrow derived stem cells into an extracellular matrix derived scaffold anchored to the subchondral bone by 3D printed polymeric supports. By recruiting endogenous cells into a supporting scaffold, ANCHOR will obviate the need for pre-seeding scaffolds with cells prior to implantation into cartilage defects, thereby dramatically reducing the cost and complexity of the repair procedure. It will also overcome the need for suturing of a scaffold into a cartilage defect, which is a very time consuming and technically challenging surgical procedure. Finally, the inherent chondro-inductivity of the cartilage ECM derived scaffolds developed by the applicant will maximise the potential for hyaline cartilage regeneration. The project will leverage the applicants extensive experience in ECM derived biomaterials and 3D printing to develop a new product with significant commercial potential. The impact of ANCHOR will be multi-faceted: it will transform how damaged joints are treated by orthopaedic surgeons, it will create economic value through the commercialization of IP, and most importantly it will improve patient experience and their long-term health and well-being.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["779909"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["UNIVERSITAT ZURICH", "UNIVERSITAT ZURICH"], "EU_Contribution": ["EUR 1 288 125"], "Project_Title": ["Tax Evasion in Developing Countries. The Role of Firm Networks"], "Total_Cost": ["EUR 1 288 125"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["DEVTAXNET"], "Technology_Description": "Tax evasion leads to billions of Euros of losses in government revenue around the world. This does not only affect public budgets, but can also create large distortions between activities that are fully taxed and others that escape taxation through evasion. These issues are particularly severe in developing countries, where evasion is especially high and governments struggle to raise funds for basic services and infrastructure, while at the same time trying to grow independent of international aid.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["758984"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["STICHTING KATHOLIEKE UNIVERSITEIT BRABANT", "STICHTING KATHOLIEKE UNIVERSITEIT BRABANT"], "EU_Contribution": ["EUR 1 499 854"], "Project_Title": ["The Time is Now: Understanding Social Network Dynamics Using Relational Event Histories"], "Total_Cost": ["EUR 1 499 854"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["TIMEISNOW"], "Technology_Description": "Relational event history data are becoming increasingly available due to new technical developments. These data contain detailed information about who interacted with whom in a network and when. For example, employees wear sociometric badges storing time-stamped interactions between colleagues, classrooms are monitored to observe interactions between teachers and students, and police databases store violent interactions between criminal gangs in city districts.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["758791"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITEIT MAASTRICHT", "UNIVERSITEIT MAASTRICHT"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Smart wavy patterned implants with instructive properties for tissue regeneration by controllingthe degree of fibers buckling."], "Total_Cost": ["EUR 150 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["BUCKLING BRIDGES"], "Technology_Description": "In the pursuit for engineering CELL HYBRIDGE regenerative medicine implants able to regenerate skeletal tissues by controlling adult stem cell activity, we have developed an innovative method to successfully improve cell migration into electrospun scaffolds. Whereas this has a direct impact in CELL HYBRIDGE as part of the planned activities, we unexpectedly discovered that the same scaffolds display wavy patterns that have a direct influence on cell differentiation by enhancing their intrinsic capacity to produce growth factors. ", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["779939"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 1 499 585"], "Project_Title": ["Photon Management for Solar Energy Harvesting with Hybrid Excitonics"], "Total_Cost": ["EUR 1 499 585"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["SOLARX"], "Technology_Description": "In nature, biological light harvesting complexes use antennas molecules to harvest photons, generate excitons and then funnel them to the reaction centre where their energy is used to drive photosynthesis. Inspired by this paradigm, SOLARX will explore new strategies for photon management in solar energy harvesting, based on the transfer and manipulation of excitons at hybrid interfaces. At the core of SOLARX is our development of a new femtosecond transient absorption imaging technique with sub-10fs time resolution and sub-diffraction limit spatial resolution. This opens completely new possibilities to explore excitonic physics at the nanoscale, directly visualising not just the motion of excitons but understanding how vibronic coupling and local structure affects their dynamics. Building on this platform we will deliver ground-breaking new insights into excitonic process in and at the interfaces between organic semiconductors, quantum dots, 2D monolayer semiconductors and lanthanide doped nanoparticles. We will elucidate the fundamental nanoscale dynamics of: (1) endothermic singlet fission, (2) the injection of triplet excitons into lanthanide doped nanoparticles and (3) the motion of excitons in 2D monolayer semiconductors and how these excitons can be funnelled over \u00b5m length scales to be transferred to quantum dots. We will then use these insights to develop proof of concept demonstrations of structures which harvest photons across the visible and NIR, efficiently converting high energy visible photons to two NIR photons and then concentrating these photons within structures with the potential to achieve concentration factors well above 100, thus concentrating light to drastically reduce the number of PV panels and hence dramatically reducing the cost of solar energy. SOLARX will thus explore and elucidate fundamental new excitonic physics and use these insights to bring a paradigm shift to solar energy harvesting technologies.", "To": ["2023-03-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-04-01"], "Project_ID": ["758826"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["ECOLE POLYTECHNIQUE", "ECOLE POLYTECHNIQUE"], "EU_Contribution": ["EUR 1 498 028,42"], "Project_Title": ["Hydrodynamics, holography and strongly-coupled quantum matter"], "Total_Cost": ["EUR 1 498 028,42"], "Country": ["France", "France"], "Project_ACR": ["HHQM"], "Technology_Description": "The dynamics of weakly-coupled quantum matter can be solved by techniques deriving from perturbative quantum field theory. Conventional metals are described by long-lived quasiparticles (Fermi liquids). No such methods are available for strongly-coupled quantum matter where quasiparticles are short-lived, like the Quark-Gluon-Plasma, high Tc superconductors (HTCs) or graphene near the charge neutrality point.", "To": ["2023-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["758759"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["CENTRE INTERNACIONAL DE METODES NUMERICS EN ENGINYERIA", "CENTRE INTERNACIONAL DE METODES NUMERICS EN ENGINYERIA"], "EU_Contribution": ["EUR 149 991"], "Project_Title": ["Computational catalog of multiscale materials: a plugin library for industrial finiteelement codes"], "Total_Cost": ["EUR 149 991"], "Country": ["Spain", "Spain"], "Project_ACR": ["CATALOG"], "Technology_Description": "The Proof of Concept CATALOG will explore the industrial applicability and potential for commercialization of a prototype of a \u201ccomputational multiscale material catalog\u201d, to exploit HPROM (high\u2010performance reduced order modeling), a technology developed in the ERC Advanced Grant COMP-DES-MAT for advanced material simulation. CATALOG will provide extremely fast and accurate multiscale capabilities to existing commercial Finite Element Analysis Solvers (FEAS), greatly enhancing their standard simulation performance. This solution effectively addresses the current need for high-performance simulations, currently not provided by established multiscale approaches.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["779611"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["THE UNIVERSITY OF LIVERPOOL", "THE UNIVERSITY OF LIVERPOOL"], "EU_Contribution": ["EUR 1 475 560"], "Project_Title": ["Influence-based Decision-making in Uncertain Environments"], "Total_Cost": ["EUR 1 475 560"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["INFLUENCE"], "Technology_Description": "Decision-theoretic sequential decision making (SDM) is concerned with endowing an intelligent agent with the capability to choose actions that optimize task performance. SDM techniques have the potential to revolutionize many aspects of society and recent successes, e.g., agents that play Atari games\u00a0and beat a world champion in the game of Go, have sparked renewed interest in this field.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["758824"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITY OF BRISTOL", "UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 1 499 611"], "Project_Title": ["Genetic, behavioural and cognitive mechanisms underpinning the association between mother and offspring mental health problems: mental (M) health (H) intergenerational transmission (INT) -(MHINT)"], "Total_Cost": ["EUR 1 499 611"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["MHINT"], "Technology_Description": "Despite decades of research, and the introduction of parenting interventions, children of mentally ill mothers remain substantially more likely to have mental health problems themselves. I propose to shed new light on why mental health problems in a mother are passed on to her child, and help break this reinforcing cycle of mental health risk across generations. In order to harness the potential of modifying parenting for the prevention of child mental health risk, I will study parenting using more detailed, ecologically valid and genetically sensitive designs than have been done before.", "To": ["2022-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["758813"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON", "UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 1 458 345"], "Project_Title": ["Gauging the Risk of Incidents of Extremist Violence Against Non-Combatant Entities"], "Total_Cost": ["EUR 1 458 345"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["GRIEVANCE"], "Technology_Description": "GRIEVANCE seeks to make significant advances in increasing our understanding, and thereby reducing the risk, of extremist violence against non-combatants. An inter-disciplinary project underpinned by crime prevention principles is needed to help quantify the risk of such offences. The barbarity of such violent acts, coupled with the fact that participation in them is characterised by an extremely low base rate, has led researchers to seek out individual qualities of the offender with a particular focus upon what radicalisation is and how its drivers can be countered. This search has proven unproductive and impractical. In fact, it has most likely limited and unduly narrowed a wider consideration of the ways in which social scientists can bring what conceptual tools we have to bear on the problem of controlling and managing such behaviour. By doing so, this project shifts the focus from individual qualities (what we think terrorists and other similar offenders \u201care\u201d) to a consideration of the situational qualities of their behaviour \u2013 in other words, what violent offenders do and how they do it (Horgan, 2009: 143). This is consistent with developments in the area of crime control (Cornish and Clarke, 1986; Brantingham & Brantingham, 1981) and crime science more generally. More specifically, GRIEVANCE will utilise a number of unique datasets to understand the risk of extremist violence across a number of phases of analysis. GRIEVANCE characterises risk in terms of a process and dedicates a work package (WP) to each stage of the process from the risk of radicalisation (WP1), to the risk of recruitment (WP2), to the risk of violent action (WP3), to the temporal (WP4) and spatial (WP5) risk of offending behaviour followed by an assessment of the risk of adverse consequences from intervention (WP6). GRIEVANCE will both synthesise the existing knowledge within the literature and produce innovative new findings by utilising cutting edge inter-disciplinary research methods.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["758834"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 476 672"], "Project_Title": ["Theoretical and observational consequences of the Geometrical Destabilization of Inflation"], "Total_Cost": ["EUR 1 476 672"], "Country": ["France", "France"], "Project_ACR": ["GEODESI"], "Technology_Description": "The GEODESI project aims at interpreting current and forthcoming cosmological observations in a renewed theoretical framework about cosmological inflation and its ending. The simplest toy models of inflation economically explain all current data, leaving no observational clue to guide theorists towards a finer physical understanding. In this context, I very recently unveiled an hitherto unnoticed instability at play in the primordial universe that potentially affects all inflationary models and drastically modifies the interpretation of cosmological observations in terms of fundamental physics. The so-called Geometrical Destabilization of inflation reshuffles our understanding of the origin of structures in the universe, offers a new mechanism to end inflation, and promises unrivaled constraints on high-energy physics. It is crucial to develop this fresh look before a host of high-quality data from large-scale structure surveys and cosmic microwave background observations become available within the 5 year timescale of the project.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-02-01"], "Project_ID": ["758792"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE", "INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["In vivo functional screens to decipher mechanisms of stochastically- and mutationally-induced chemoresistance in Acute Myeloid Leukemia"], "Total_Cost": ["EUR 1 500 000"], "Country": ["France", "France"], "Project_ACR": ["AltCheM"], "Technology_Description": "Acute Myeloid Leukemia (AML), the most common leukemia diagnosed in adults, represents the paradigm of resistance to front-line therapies in hematology. Indeed, AML is so genetically complex that only few targeted therapies are currently tested in this disease and chemotherapy remains the only standard treatment for AML since the past four decades. Despite an initial sustained remission achieved by chemotherapeutic agents, almost all patients relapse with a chemoresistant minimal residual disease (MRD). The goal of my proposal is to characterize the still poorly understood biological mechanisms underlying persistence and emergence of MRD.", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-03-01"], "Project_ID": ["758848"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["INSTITUT CURIE", "INSTITUT CURIE"], "EU_Contribution": ["EUR 1 497 500"], "Project_Title": ["A new paradigm for centromere biology:Evolution and mechanism of CenH3-independent chromosome segregation in holocentric insects"], "Total_Cost": ["EUR 1 497 500"], "Country": ["France", "France"], "Project_ACR": ["CENEVO"], "Technology_Description": "Faithful chromosome segregation in all eukaryotes relies on centromeres, the chromosomal sites that recruit kinetochore proteins and mediate spindle attachment during cell division. Fundamental to centromere function is a histone H3 variant, CenH3, that initiates kinetochore assembly on centromeric DNA. CenH3 is conserved throughout most eukaryotes; its deletion is lethal in all organisms tested. These findings established the paradigm that CenH3 is an absolute requirement for centromere function. My recent findings undermined this paradigm of CenH3 essentiality. I showed that CenH3 was lost independently in four lineages of insects. These losses are concomitant with dramatic changes in their centromeric architecture, in which each lineage independently transitioned from monocentromeres (where microtubules attach to a single chromosomal region) to holocentromeres (where microtubules attach along the entire length of the chromosome). Here, I aim to characterize this unique CenH3-deficient chromosome segregation pathway. Using proteomic and genomic approaches in lepidopteran cell lines, I will determine the mechanism of CenH3-independent kinetochore assembly that led to the establishment of their holocentric architecture. Using comparative genomic approaches, I will determine whether this kinetochore assembly pathway has recurrently evolved over the course of 400 million years of evolution and its impact on the chromosome segregation machinery.", "To": ["2023-03-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-04-01"], "Project_ID": ["758757"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["THE HEBREW UNIVERSITY OF JERUSALEM", "THE HEBREW UNIVERSITY OF JERUSALEM"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Dissecting Regulatory Networks That Mediate Dendritic Cell Suppression"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Israel", "Israel"], "Project_ACR": ["CANCER-DC"], "Technology_Description": "Recent advances have shown that therapeutic manipulations of key cell-cell interactions can have dramatic clinical outcomes. Most notable are several early successes in cancer immunotherapy that target the tumor-T cell interface. However, these successes were only partial. This is likely because the few known interactions are just a few pieces of a much larger puzzle, involving additional signaling molecules and cell types. Dendritic cells (DCs), play critical roles in the induction/suppression of T cells. At early cancer stages, DCs capture tumor antigens and present them to T cells. However, in advanced cancers, the tumor microenvironment (TME) disrupts the crosstalk between DCs and T cells. ", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["758735"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Reconstructing human cortex development and malformation with single-cell transcriptomics"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["ORGANOMICS"], "Technology_Description": "Technologies to sequence single-cell transcriptomes (scRNA-seq) are revolutionizing our ability to analyze cell composition and differentiation in complex tissues. In parallel, recent innovations allow the generation of three-dimensional tissues from stem cells that recapitulate human development. In this proposal, we will focus on human cortex development modelled by cerebral organoids. Our vision is to create an integrative single-cell transcriptomic platform to reconstruct cerebral organoid development, and dissect network alterations that lead to human brain malformations. Our project will be advanced through the following objectives: ", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2018-01-01"], "Project_ID": ["758877"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITAETSKLINIKUM HAMBURG-EPPENDORF", "UNIVERSITAETSKLINIKUM HAMBURG-EPPENDORF"], "EU_Contribution": ["EUR 1 490 825"], "Project_Title": ["Development of strategies to eliminate cancer cells from the bone marrow"], "Total_Cost": ["EUR 1 490 825"], "Country": ["Germany", "Germany"], "Project_ACR": ["ELIMINATE"], "Technology_Description": "The bone marrow (BM) represents the prime location in which cancer cells survive aggressive treatments. This poses a major health challenge because the mortality rate of patients with curable cancer doubles if tumor cells persist in the BM. One unresolved question is why the immune system fails to eradicate cancer cells from this microenvironment even though it represents a lymphatic organ. Surprisingly, despite the ongoing revolution in immune oncology, the regulation and potential therapeutic activation of the immune response in the BM still remains largely unexplored. In this grant application a new line of research is proposed with the overall objective of understanding the cellular and molecular mechanisms, which control anti-cancer immune responses in the BM. The originality of this proposal relates to the hypothesis that innate and adaptive immune cells are suppressed by stroma cells in the BM. Therefore, we will conduct a comprehensive phenotypic and functional profiling of immune and stroma cells in the BM of cancer patients with and without persisting tumor cells. Based on these insights we will develop novel strategies to harness the immune system to eliminate malignant cells from the BM. The ground-breaking nature of the project is that it will shed light on the unappreciated immune microenvironment in the BM. Its specific strength lies in the multidisciplinary design encompassing informative patient cohorts, state-of-the-art mouse models and cutting-edge technologies including Next-Generation-Sequencing as well as innovative drug candidates. Hereby I can build on my internationally recognized expertise in the BM microenvironment field, which has already led to the successful development of a clinical-stage drug. Novel strategies to eliminate malignant cells from the bone marrow are of utmost medical importance because they would increase the cure rate of cancer patients.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["758713"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["DANMARKS TEKNISKE UNIVERSITET", "DANMARKS TEKNISKE UNIVERSITET"], "EU_Contribution": ["EUR 1 496 000"], "Project_Title": ["ATOMic Insight Cavity Array Reactor"], "Total_Cost": ["EUR 1 496 000"], "Country": ["Denmark", "Denmark"], "Project_ACR": ["ATOMICAR"], "Technology_Description": "The goal of ATOMICAR is to achieve the ultimate sensitivity limit in heterogeneous catalysis: ", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["758495"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["THE UNIVERSITY OF EDINBURGH", "THE UNIVERSITY OF EDINBURGH"], "EU_Contribution": ["EUR 1 481 154"], "Project_Title": ["The emergence and evolution of linguistic tone"], "Total_Cost": ["EUR 1 481 154"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["EVOTONE"], "Technology_Description": "This project will investigate the origins, acquisition, and evolution of linguistic tone: the use of pitch to distinguish between the meaning of words. Despite the typological ubiquity of tone, there is still no phonetic, structural, or psychological model that explains how and why tones emerge (or fail to emerge) in language after language, nor how they evolve once they are formed. This is because there has never been a systematic analysis of the principles that govern the evolution of tone systems. EVOTONE will provide the first comprehensive study of tonal emergence and evolution, combining detailed phonetic and perceptual studies of Himalayan and Southeast Asian minority languages with innovative experimental methodologies and large-scale computational analysis of the structural principles correlated with the emergence of tone. ", "To": ["2023-05-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-06-01"], "Project_ID": ["758605"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["THE QUEEN'S UNIVERSITY OF BELFAST", "THE QUEEN'S UNIVERSITY OF BELFAST"], "EU_Contribution": ["EUR 1 876 496"], "Project_Title": ["Type Ia supernovae: from explosions to cosmology"], "Total_Cost": ["EUR 1 876 496"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["SUPERSTARS"], "Technology_Description": "Type Ia supernovae (SNe Ia) are the incredibly luminous deaths of white dwarfs in binaries. They play a vital role in chemical enrichment, galaxy feedback, stellar evolution, and were instrumental in the discovery of dark energy. However, what are the progenitor systems of SNe Ia, and how they explode remains a mystery. My recent work has concluded the controversial result that there may be more than one way to produce SNe Ia. As SN Ia cosmology samples reach higher precision, understanding subtle differences in their properties becomes increasingly important. A surprising diversity in white-dwarf explosions has also been uncovered, with a much wider-than-expected range in luminosities, light-curve timescales and spectral properties. A key open question is \u2018What explosion mechanisms result in normal SNe Ia compared to more exotic transients?\u2019", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["758638"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSIDAD DE GRANADA", "UNIVERSITE DES SCIENCES ET TECHNOLOGIES DE LILLE - LILLE I", "GENERALIZED RETRIEVAL OF ATMOSPHERE AND SURFACE PROPERTIES EN ABREGE GRASP", "UNIVERSIDAD DE VALLADOLID", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "FREIE UNIVERSITAET BERLIN", "Goddard Space Flight Center", "University System of Maryland", "A.M. Prokhorov General Physics Institute of Russian Academy of Sciences", "B.I. Stepanov Institute of Physics of the National Academy of Sciences of Belarus"], "EU_Contribution": ["EUR 877 500"], "Project_Title": ["Development of GRASP radiative transfer code for the retrieval of aerosol microphysics vertical-profiles from space measurements and its impact in ACE mission"], "Total_Cost": ["EUR 877 500"], "Country": ["Spain", "France", "France", "Spain", "France", "Germany", "Belgium", "United States", "Russia", "Belarus"], "Project_ACR": ["GRASP-ACE"], "Technology_Description": "This project deals with reducing the uncertainties associated with the knowledge of aerosol microphysical vertical profiles worldwide through the use of new space-borne measurements. This objective links with the goal of the last IPCC 2013 to reduce uncertainties in aerosol direct effects, particularly in the knowing of absorption profiles. The approach we plan to develop is the development and applicability of the Generalized Retrieval of Atmosphere and Surface Properties (GRASP) for new space borne systems. GRASP has been already applied successfully to the POLDER/PARASOL system providing column-integrated aerosol microphysics and absorption. However, the new LIDAR space-borne sensors open new possibilities. To that end, we plan to study the details in constraints of the current techniques for the retrieval of aerosol microphysics from multi-wavelength lidar alone (known as the 3b+2a configuration), and will make evaluation studies versus in-situ instruments from large field campaigns such as DISCOVER-AQ and SEACR4S from NASA or SHADOW from the University of Lille. However, lidar measurements are difficult and usually presents low signal-to-noise ratio, particularly during daytime. We plan here to develop a joint inversion that uses combine measurements of lidar and polarimetric space-borne systems. Such approach is the core of the upcoming Aerosol-Clouds-Ecosystems (ACE) NASA mission. The development of this task will involve the use of synthetic database simulated using the NASA GEOS-5 model which will be used as reference. Different configurations of lidar and polarimeters will be studied to invert microphysical parameters. The results of this task will be also used for defining cost-effective ACE mission. Also, joint inversion will be evaluated using experimental measurements on NASA field campaigns that include airborne lidar systems such as HSRL-2 and Airborne Cloud-Aerosol Transport System (ACATS) and polarimeters such as the Multiangle SpectroPolarimetric.", "To": ["2022-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Other", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2018-03-01"], "Project_ID": ["778349"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["PANEPISTIMIO THESSALIAS", "UNIVERSIDADE DO PORTO", "CENTRO DE ESTUDIOS SUPERIORES DE LA INDUSTRIA FARMACEUTICA SA", "CHRISTOS PAPADOPOULOS & SIA O.E."], "EU_Contribution": ["EUR 828 000"], "Project_Title": ["Nutraceutical supplementation based on colostrum for prevention of osteoporosis"], "Total_Cost": ["EUR 828 000"], "Country": ["Greece", "Portugal", "Spain", "Greece"], "Project_ACR": ["COLOSTEO"], "Technology_Description": "Osteoporosis constitutes a major public health concern. The economic burden of osteoporotic fractures in EU is expected to increase 25% by 2025 compared to 2010. These estimates may indicate an inefficiency of current drugs for osteoporosis. Actually, the use of pharmacological agents for osteoporosis has been decreasing in EU, probably due to the reported side effects. Therefore, there is a need for innovative agents to reduce the burden of osteoporosis. Colostrum is a promising agent against bone loss since it has natural constituents that are directly involved in bone metabolism. As a nutraceutical, colostrum confers an advantage over pharmacological drugs since it can avoid side effects. However, the possibility of its use as a nutraceutical agent for osteoporosis have only received attention within the scientific community. The knowledge produced on the effects of colostrum on bone metabolism has not yet been transferred to the market because academic institutions lack on expertise to create a new product. On the other hand, industry has knowledge on product development, but lack expertise on research skills. In accordance, what hinders the creation of an innovative product based on colostrum for prevention of osteoporosis is the absence of an intersectorial collaboration. As consequence, there is a clearly gap between research on the matter and its application. COLOSTEO aims to fill in this gap by creating an intersectorial collaboration to exchange knowledge and expertise towards the creation of an innovative nutraceutical product based on colostrum to prevent osteoporosis. This aim will be achieved by bridging two academic with two industrial institutions that through intersectorial secondments will exchange knowledge, ideas and expertise towards the creation of an innovative nutraceutical product based on colostrum to prevent osteoporosis.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Greece"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-01-01"], "Project_ID": ["778277"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["HELSINGIN YLIOPISTO", "HELSINGIN YLIOPISTO"], "EU_Contribution": ["EUR 1 470 665"], "Project_Title": ["Competence and Success in Epistemology and Beyond"], "Total_Cost": ["EUR 1 470 665"], "Country": ["Finland", "Finland"], "Project_ACR": ["EpComp"], "Technology_Description": "This project formulates and defends a novel approach in epistemology, demonstrating how it solves a range of key problems in the field. New frontiers of research are opened up by applying the core lessons learnt in epistemology to the study of practical reason and ethics.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["758539"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSIDAD CARLOS III DE MADRID", "UNIVERSIDAD CARLOS III DE MADRID", "UNIVERSIDAD NACIONAL DE EDUCACION A DISTANCIA", "WISSENSCHAFTSZENTRUM BERLIN FUR SOZIALFORSCHUNG GGMBH"], "EU_Contribution": ["EUR 1 499 572"], "Project_Title": ["Effort and Social Inequality: Advancing Measurement and Understanding Parental Origin Effects"], "Total_Cost": ["EUR 1 499 572"], "Country": ["Spain", "Spain", "Spain", "Germany"], "Project_ACR": ["EFFORT"], "Technology_Description": "This project aims to understand the role of effort in the reproduction of social inequality. While large-scale test programs like PISA have produced impressive amounts of data on the determinants of cognitive abilities, there is scant evidence on socio-economic differences in cognitive effort. Better understanding the social origins of effort pushes the frontier of knowledge on intergenerational mobility and allows improving equality of opportunity. Specifically, the aim of the project is to answer three research questions:", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2018-03-01"], "Project_ID": ["758600"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["HELSINGIN YLIOPISTO", "HELSINGIN YLIOPISTO"], "EU_Contribution": ["EUR 1 495 584"], "Project_Title": ["Digital Grammar of Greek Documentary Papyri"], "Total_Cost": ["EUR 1 495 584"], "Country": ["Finland", "Finland"], "Project_ACR": ["PapyGreek"], "Technology_Description": "The project creates a new Digital Grammar of Greek Documentary Papyri. It fills a void in Greek scholarship: the papyrological corpus represents the Post-Classical variety of Greek, a bridge between Classical and Medieval Greek, which has hitherto been very difficult to use as a source for studying historical linguistics. This project will develop new digital methods for studying this fragmentary but vast text corpus. ", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["758481"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["STOCKHOLMS UNIVERSITET", "STOCKHOLMS UNIVERSITET"], "EU_Contribution": ["EUR 1 497 650,02"], "Project_Title": ["MicroRNA functions in single cells"], "Total_Cost": ["EUR 1 497 650,02"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["miRCell"], "Technology_Description": "It is now becoming apparent that genes are regulated not only by transcription, but also by thousands of post-transcriptional regulators that can stabilize or degrade mRNAs. Some of the most important regulators are miRNAs, short RNA molecules that are deeply conserved in sequence and are involved in numerous biological processes, including human disease. Surprisingly, transcriptomic and proteomic studies show that most miRNAs only have subtle silencing effects on their targets, suggesting additional important, but yet undiscovered functions. Thus the question is raised: if the main function of miRNAs is not to silence targets, what is it?", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["758397"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS", "AGRICULTURAL UNIVERSITY OF ATHENS", "FONDAZIONE EDMUND MACH", "BIONOS BIOTECH SL", "IGV GREENFOOD GGMBH", "EPARELLA GMBH", "FRESH FORMULA PRIVATE LIMITED COSMETICS MANUFACTURING COMPANY"], "EU_Contribution": ["EUR 1 129 500"], "Project_Title": ["Development of microalgae-based natural UV Sunscreens and Proteins as cosmeceuticals and nutraceuticals"], "Total_Cost": ["EUR 1 129 500"], "Country": ["Greece", "Greece", "Italy", "Spain", "Germany", "Austria", "Greece"], "Project_ACR": ["AlgaeCeuticals"], "Technology_Description": "The biotechnology of microalgae has gained considerable importance in recent decades, as they represent a largely untapped reservoir of novel and valuable bioactive compounds. The biological and chemical diversity of the microalgae, has been the source of unique bioactive molecules with the potential for industrial development as pharmaceuticals, cosmetics, nutritional supplements. The proposed project will combine both basic and applied research in the fields of \u2013omics technologies, biochemistry, applied and enzyme biotechnology in order to exploit microalgae resources for the development: 1) Natural UV sunscreens, based on algae mycosporine-like aminoacids, 2) Algae-based nutraceuticals as functional foods and food supplements, 3) Algae-derived proteases with applications in cosmetic (skin repair enzymes) and food industry. The implementation of the project will offer to the involved academic and SMSs the opportunity to translate scientific research into well defined knowledge-based \u2018green\u2019 products and analytical tools. Apart from scientific objectives, the project will enhance the European\u2019s capacity in the field of Blue Growth and Marine Biotechnology by exchanging interdisciplinary knowledge, developing and disseminating joint research activities, thus strengthening the intersectoral links between academia and industry for sustainable growth.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Greece"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-01-01"], "Project_ID": ["778263"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS", "ECOLE NATIONALE DES PONTS ET CHAUSSEES", "BOURNEMOUTH UNIVERSITY", "BLUESOFT SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA", "CABLENET COMMUNICATION SYSTEMS LTD", "NODALPOINT SYSTEMS"], "EU_Contribution": ["EUR 1 611 000"], "Project_Title": ["Intelligence-Driven Urban Internet-of-Things Ecosystems for Trustworthy and Circular Smart Cities"], "Total_Cost": ["EUR 1 611 000"], "Country": ["Greece", "France", "United Kingdom", "Poland", "Cyprus", "Greece"], "Project_ACR": ["IDEAL-CITIES"], "Technology_Description": "IDEAL-CITIES aims to develop, demonstrate and evaluate an open modular platform for building adaptive Internet-of-Things and Participatory Sensing (IoTPS) based Smart City applications, supported by Big Data analytics and Cloud services. IDEAL-CITIES outcomes will increase urban life quality, safety and inclusivity by enabling citizens and authorities to produce and exchange contextualised distributed intelligence and information in real-time, in a trustworthy and sustainable manner. The IDEAL-CITIES platform will foster the development and uptake of novel IoTPS-based Smart City applications and enhance the associated market base, by demonstrating new feasible ways for providing IoTPS applications and services which can contribute to urban citizen\u2019s well-being and the cities\u2019 circular economy. The IDEAL-CITIES platform will be demonstrated in the context of two fully-fledged IoTPS Applications, with a focus on mobility for the impaired and on citizen safety, in close cooperation with involved communities (a non-profit organisation for the blind and partially-sighted and four municipalities, respectively), validating the utility of the proposed platform and approach.", "To": ["2022-06-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Greece"], "Activity": ["Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-07-01"], "Project_ID": ["778229"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["LVIV POLYTECHNIC NATIONAL UNIVERSITY", "SMARTMEMBRANES GMBH", "POLITECHNIKA CZESTOCHOWSKA", "SCIENTIFIC RESEARCH COMPANY CARAT -BRANCH ENTERPRISE OF PJSC CONCERN -ELECTRON", "UNIVERSITE D'ANGERS", "POLITECHNIKA WARSZAWSKA", "PRIVATE ENTERPRISE SOFTPARTNERS", "FORSCHUNGSZENTRUM JULICH GMBH", "ENERGIA OZE SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA"], "EU_Contribution": ["EUR 1 692 000"], "Project_Title": ["Innovative Optical/Quasioptical Technologies and Nano Engineering of Anisotropic Materials for Creating Active Cells with Substantially Improved Energy Efficiency"], "Total_Cost": ["EUR 1 692 000"], "Country": ["Ukraine", "Germany", "Poland", "Ukraine", "France", "Poland", "Ukraine", "Germany", "Poland"], "Project_ACR": ["IMAGE"], "Technology_Description": "The principal goal of the project is to combine research expertise in optics, crystallography and material science with efforts in material engineering to go beyond state-of-the-art in the development of highly efficient energy saving optical cells based on electro-, acousto- and nonlinear optical effects and designed to operate in optical and quasi-optical (sub-THz) ranges.", "To": ["2022-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Ukraine"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-02-01"], "Project_ID": ["778156"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["FUNDACION BCMATERIALS - BASQUE CENTRE FOR MATERIALS, APPLICATIONS AND NANOSTRUCTURES", "UNIVERSITA DEGLI STUDI DI TORINO", "UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA", "AGENCIA VASCA DEL AGUA URA", "TEKNIMAP AMBIENTAL SL", "UNIVERSIDAD DE BUENOS AIRES", "UNIVERSIDAD DE CHILE", "THE REGENTS OF THE UNIVERSITY OF CALIFORNIA"], "EU_Contribution": ["EUR 774 000"], "Project_Title": ["International Network on Ionic Liquid Deep Eutectic Solvent Based Metal Organic Frameworks Mixed Matrix Membranes."], "Total_Cost": ["EUR 774 000"], "Country": ["Spain", "Italy", "Spain", "Spain", "Spain", "Argentina", "Chile", "United States"], "Project_ACR": ["INDESMOF"], "Technology_Description": "The main objective of INDESMOF Marie Curie RISE action is to establish a new and lasting research consortium to improve and exchange interdisciplinary and intersectoral knowledge on the design, synthesis, and characterization of advanced composite adsorbents for environmental remediation of heavy metal polluted water sources, able to provide high capacity and high selectivity filters for the industry. The main research core of INDESMOF is based on the nano-encapsulation of Deep Eutectic Solvents (DES) within the ordered porous structures of Metal Organic Frameworks (MOF), in order to obtain a highly porous MOF material, combined with the metal chelation and solvation specificity of DES. Incorporation of high-capacity high-selectivity adsorbent materials within polymeric support is a crucial challenge faces in INDESMOF towards the real application of the MOF@DES materials in water filtering systems, indispensable for mining and industrial water environmental remediation technologies. Development and improvement of advanced filtering technologies requires the joint effort of a multidisciplinary researcher collective, involving the expertise of participants on different disciplines including physics, chemistry, environmental chemistry, materials and polymer science and engineering. Background knowledge and knowhow of INDEMOF\u00b4s partners combine the complementarities and synergies needed to undertake an integrative and concerted effort through innovation and breakthrough actions towards the fabrication of advanced and specific filters for polluted water remediation. Results will be widely disseminated through publications, workshops, post-graduate courses to train new researchers, a dedicated webpage, and visits to companies working in the area. In that way, we will perform an important role in technology transfer in the design of highly active and selective adsorbents and their performance against real water polluted samples.", "To": ["2022-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["778412"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["AGRICULTURAL UNIVERSITY OF ATHENS", "UNIVERSITA CATTOLICA DEL SACRO CUORE", "INSTITUT NATIONAL D'ETUDES SUPERIEURES AGRONOMIQUES DE MONTPELLIER", "Q TECHNOLOGIES LTD", "KPAD LTD", "AGRICULTURAL & ENVIRONMENTAL SOLUTIONS", "M2S", "NEUROPUBLIC AE PLIROFORIKIS & EPIKOINONION"], "EU_Contribution": ["EUR 1 183 500"], "Project_Title": ["Implementation of integrated and innovative Precision Agriculture management strategies to reduce the occurrence of ochratoxins along the vine value chain products: grapes, raisins/currants and wine"], "Total_Cost": ["EUR 1 183 500"], "Country": ["Greece", "Italy", "France", "United Kingdom", "United Kingdom", "Greece", "France", "Greece"], "Project_ACR": ["OchraVine Control"], "Technology_Description": "The risk of mycotoxins is a global issue that represents a serious risk for human and animal health. \u039fchratoxin A (OTA) is a very toxic mycotoxin that constitutes a severe problem for viticulture and taking into account the extreme climatic events that are frequently faced in recent years, the OTA problem is arising in wine and raisins/currants. OchraVine Control project will offer an inexistent innovative, sustainable and integrated smart ICT solution (OchraVine Control DSS) considering fungal, host and environmental indicators that affect OTA contamination along the vine grape-wine value chain. The OchraVine Control DSS will allow prediction and monitoring at pre- and post-harvest level to control Aspergillus infection and OTA contamination in vine cultivation by combining epidemiological data, biological and chemical management strategies, post-havrest technologies and precision agriculture tools. OchraVine Control DSS solution will pursue a field-to-fork approach and will link and translate the information derived from the OchraRisk and OchraDetect predictive map tools and real data obtained during the monitoring controls by the OchraSensor. OchraVine Control DSS tool will be placed in an open access web platform and in combination with data from the OchraRed Integrated Management Strategy will provide risk prediction information (i.e. geographic OTA vine alerts), practical recommended solutions for OTA management and will verify the compliance with legislation requirements in a rapid and cost-effective way. The project will have a multi-actor international approach involving 3 RTDs and 5 SMEs that will exchange skills and knowledge and will all have a vital role in the design of the solutions, implementation, testing, dissemination, communication and economic exploitation.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Greece"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-01-01"], "Project_ID": ["778219"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA", "ARKEMA FRANCE", "UNIVERSITY OF SURREY", "STICHTING WAGENINGEN RESEARCH", "DANMARKS TEKNISKE UNIVERSITET", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "GREENE WASTE TO ENERGY SL", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "CHALMERS TEKNISKA HOEGSKOLA AB", "IBJ TECHNOLOGY IVS", "BIOPROCESS PILOT FACILITY BV", "CHIMAR HELLAS AE", "COMPAGNIE INDUSTRIELLE DE LA MATIERE VEGETAL CIM V"], "EU_Contribution": ["EUR 666 000"], "Project_Title": ["Renewable systems engineering for waste valorisation \u0399\u0399"], "Total_Cost": ["EUR 666 000"], "Country": ["Greece", "France", "United Kingdom", "Netherlands", "Denmark", "Switzerland", "Spain", "United Kingdom", "Sweden", "Denmark", "Netherlands", "Greece", "France"], "Project_ACR": ["RENESENG II"], "Technology_Description": "The project goal is to further advance the emerging area of Bio - process - systems engineering (BPSE) by capitalizing the recent advances and ITN of RENESENG (FP7 - PEOPLE - ITN) toward the following project objectives :", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Greece"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-01-01"], "Project_ID": ["778332"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["UNIDAD NEURO-RHB SOCIEDAD LIMITADA", "FUNDACION UNIVERSIDAD LOYOLA ANDALUCIA", "FONDAZIONE SANTA LUCIA", "ISTITUTI CLINICI SCIENTIFICI MAUGERI SOCIETA' PER AZIONI SOCIETA' BENEFIT", "SCHON KLINIK BAD AIBLING SE & CO KG", "ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON", "UNIVERSITE DE LIEGE", "UNIVERSITA DEGLI STUDI DELLA CAMPANIA LUIGI VANVITELLI", "GUGER TECHNOLOGIES OG", "UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA"], "EU_Contribution": ["EUR 1 129 500"], "Project_Title": ["Disorders of Consciousness (DoC): enhancing the transfer of knowledge and professional skills on evidence-based interventions and validated technology for a better management of patients"], "Total_Cost": ["EUR 1 129 500"], "Country": ["Spain", "Spain", "Italy", "Italy", "Germany", "Greece", "Belgium", "Italy", "Austria", "Italy"], "Project_ACR": ["DoCMA"], "Technology_Description": "The overall goal of DoCMA is to enhance international research on Disorders of Consciousness (DoC) by strengthen the collaboration among project participants to leverage the shared scientific and expert know-how in the field. ", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Spain"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["778234"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 499 375"], "Project_Title": ["The missing link between Perception and Cognition: The case of multiple-person scenarios"], "Total_Cost": ["EUR 1 499 375"], "Country": ["France", "France"], "Project_ACR": ["THEMPO"], "Technology_Description": "Seeing persons among other persons interacting with each other and trying to understand what is happening is a fundamental task for our daily life. How the brain manifests the representational and integrative capacity necessary for this function is beyond our current understanding. THEMPO sees in the study of multiple-person scenarios an opportunity to address how human cognition deals with real-word social interactions and, more generally, how the information process is devised to go from a perceptual representation of entities (e.g. bodies) to a representation of the abstract relations that pull those entities together into a structured unit (i.e. a social event). Multiple-person scenarios are thus a case study to address the missing link between perception and higher cognition, and to understand how early visual perceptual representations make contact with relational/symbolic representations. THEMPO will pursue different levels of explanation, defining the sequence of information-processing stages involved, and their implementation in the brain in terms of large-scale network organization (functional, causal and hierarchical relations among perceptual and non-perceptual neural processes). It will further study the neural (linear and/or nonlinear) operations to transform perceptual information along the way toward abstraction. This will be accomplished by combining fine cognitive manipulations, imaging and neurostimulation techniques (fMRI, TMS), and advanced analytical approaches based on multivariate analyses of neural response patterns to define the operations behind neural activity in humans. THEMPO will culminate in the formulation of a model that will serve as a test bed to address individual variations in perceptual and neural combinatorial operations and, possibly, uncover the roots of altered social cognition. THEMPO is designed to build upon itself, from relatively simple stages to high-risk, high-gain objectives, as a safeguard to success.", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-03-01"], "Project_ID": ["758473"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["THE UNIVERSITY OF SHEFFIELD", "VYSOKE UCENI TECHNICKE V BRNE", "UNIVERSITA DEGLI STUDI DI PAVIA", "TECHNISCHE UNIVERSITEIT DELFT", "NV PWN WATERLEIDINGBEDRIJF NOORD-HOLLAND", "DVGW DEUTSCHER VEREIN DES GAS- UND WASSERFACHES - TECHNISCH-WISSENSCHAFTLICHER VEREIN EV", "UNIVERSITAT POLITECNICA DE VALENCIA", "STICHTING WATERNET", "KWR WATER B.V.", "INSTITUT NATIONAL DE RECHERCHE EN SCIENCES ET TECHNOLOGIES POUR L'ENVIRONNEMENT ET L'AGRICULTURE", "THE UNIVERSITY OF EXETER", "NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU", "FACULTY OF CIVIL ENGINEERING", "JAVNO KOMUNALNO PREDUZECE VODOVOD IKANALIZACJA PANCHEVO", "CONSTRUCCIONES Y CANALIZACIONES CYCA SOCIEDAD LIMITADA", "University of Cincinnati", "REGENTS OF THE UNIVERSITY OF COLORADO", "THE REGENTS OF THE UNIVERSITY OF CALIFORNIA"], "EU_Contribution": ["EUR 243 000"], "Project_Title": ["Water Quality in Drinking Water Distribution Systems."], "Total_Cost": ["EUR 243 000"], "Country": ["United Kingdom", "Czech Republic", "Italy", "Netherlands", "Netherlands", "Germany", "Spain", "Netherlands", "Netherlands", "France", "United Kingdom", "Norway", "Serbia", "Serbia", "Spain", "United States", "United States", "United States"], "Project_ACR": ["Wat-Qual"], "Technology_Description": "Safe drinking water is paramount for the health and wellbeing of all populations. Unsafe drinking water can contain pathogenic microorganisms and/or chemicals that can make people immediately unwell or can potentially cause serious illness over prolonged exposures. Within the EU, water is extracted from surface and groundwater sources and treated to comply with EU drinking water standards under the Water Framework Directive and Drinking Water Directive. The water is then circulated through the drinking water distribution system (DWDS). During travel within the DWDS, water quality can deteriorate due to microbiological growth, chemical reactions, interactions with ageing and deteriorating infrastructure, and through maintenance and repair activities. ", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["778136"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["UNIVERSITE DE STRASBOURG", "UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA", "UNIVERSITA DEGLI STUDI DI PARMA", "NANOMOL TECHNOLOGIES SA", "ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING MCGILL UNIVERSITY", "UNIVERSIDAD DE LA HABANA", "THE REGENTS OF THE UNIVERSITY OF CALIFORNIA"], "EU_Contribution": ["EUR 598 500"], "Project_Title": ["Hybrid Nanostructured Oligonucleotide Platforms for Biomedical Applications"], "Total_Cost": ["EUR 598 500"], "Country": ["France", "Italy", "Italy", "Spain", "Canada", "Cuba", "United States"], "Project_ACR": ["Nano-OligoMed"], "Technology_Description": "Nanotechnology has received widespread attention in the last several decades due to the technological breakthroughs it has enabled across sectors from electronics to medicine. Towards the great challenges that nanotechnology arise, Nano-OligoMed has the ambition to establish and support a network of international collaboration, enabling a collaborative scientific team to effectively use a diversity of approaches and strategies to generate and test hybrid nanomaterials for the efficient and safe systemic delivery of oligonucleotide-based therapeutic agents. To this end, we have set-up a joint multidisciplinary scientific collaborative programme that through exchange, international mobility, and strongly collaborative transfer of knowledge and training activities between 4 European and 3 extra-European countries, will bring together leading experts under the field of \u201cnanomaterials in biomedicine\u201d. The scientific aim of Nano-OligoMed is the creation of degradable hybrid structures that combine the rigid, inert silica with the delicate programmable oligonucleotides or artificial oligonucleotide-mimics. The possibility to develop novel oligonucleotide-based materials will enable a) the degradation of the drug carrier at the presence of a specific input as a function of the intrinsic bio-responsive feature of oligonucleotides, b) the activation of a therapeutic function as a result of the bio-molecular interaction between the oligonucleotide-based material and the molecular target (i.e. miRNAs) and c) the delivery of the chemical payload (DNA and/or artificial mimics, even in combination with cancer drugs) upon cell internalization. The international academic networking, the broadening of the research skills, the educational activities, will provide to young (PhD students) and senior scientists, specific competences in the field of materials sciences, nanotechnology, molecular biology and molecular medicine.", "To": ["2021-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["778133"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI DI TRIESTE", "SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI DI TRIESTE"], "EU_Contribution": ["EUR 1 055 317"], "Project_Title": ["Atomic Gauge and Entanglement Theories"], "Total_Cost": ["EUR 1 055 317"], "Country": ["Italy", "Italy"], "Project_ACR": ["AGEnTh"], "Technology_Description": "AGEnTh is an interdisciplinary proposal which aims at theoretically investigating atomic many-body systems (cold atoms and trapped ions) in close connection to concepts from quantum information, condensed matter, and high energy physics. The main goals of this programme are to:", "To": ["2023-04-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-05-01"], "Project_ID": ["758329"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["BRUNEL UNIVERSITY LONDON", "BRUNEL UNIVERSITY LONDON"], "EU_Contribution": ["EUR 1 407 675,63"], "Project_Title": ["Refiguring Conservation in/for 'the Anthropocene': The Global Lives of the Orangutan"], "Total_Cost": ["EUR 1 407 675,63"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["GLO"], "Technology_Description": "In recent years, conservationists have engaged in heated debates about whether and how conservation should respond to the challenges posed by \u2018the Anthropocene\u2019\u2014a term increasingly used to encapsulate the overwhelming, transformative impact of human activity on the Earth system. How are these debates\u2014and the wider \u2018Anthropocenic\u2019 awareness they embody\u2014reshaping conservation philosophy, strategy and practice? How are they manifested in and across diverse contexts? How, conversely, are global conservation developments and \u2018Anthropocenic\u2019 phenomena apprehended and reshaped on the ground? This project explores such urgent questions through an unprecedented study of the global nexus of orangutan conservation at a unique historical juncture marked by flux and uncertainty. Combining in-depth ethnography and multiply-scaled cross-cultural comparison, it approaches orangutan conservation as a sprawling, uneven terrain across which the rapidly-evolving relationship between conservation and \u2018the Anthropocene\u2019 is being played out. Its objectives are 1) to examine if and how contemporary conservation is being \u2018scaled up\u2019 and re(con)figured in and for \u2018the Anthropocene\u2019; and 2) to cut \u2018the Anthropocene\u2019 down to size by exploring how it is experienced, conceptualized, contested or indeed refused across multiple conservation settings. Comprising four interlinked studies to be carried out simultaneously at the main nodes of orangutan conservation, this project seeks to pioneer a new synchronic, multi-sited approach to the analysis of global conservation and lay the groundwork for an empirically-driven, theoretically ambitious new field of scholarship on conservation in/for \u2018the Anthropocene\u2019\u2014one that will revitalize social scientific understandings of conservation while adding much-needed empirical depth and nuance to emerging cross-disciplinary discussions about \u2018the Anthropocene\u2019.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["758494"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 499 875"], "Project_Title": ["Nanoparticles as Partners in Frustrated Lewis Pairs: Boosting the Surface Reactivity of Inorganic Nanoparticles"], "Total_Cost": ["EUR 1 499 875"], "Country": ["France", "France"], "Project_ACR": ["NanoFLP"], "Technology_Description": "Associating bulky and strong Lewis acid and base creates a Frustrated Lewis Pair (FLP). Traditionally, both FLP partners are molecules. Molecular FLPs have shown excellent abilities to catch and dissociate small molecules such as H2 in a heterolytic way, under mild conditions. The driving force is the destabilization of the initial acid-base adduct, sterically frustrated: it liberates a reactive pocket that catches the small molecule guest, and strongly lowers the activation energy for bond dissociation. ", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["758480"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 499 632"], "Project_Title": ["De novo structural elucidation of functional organic powders at natural isotopic abundance"], "Total_Cost": ["EUR 1 499 632"], "Country": ["France", "France"], "Project_ACR": ["STRUCTURE"], "Technology_Description": "Structure holds the key to many of the physical world\u2019s most intriguing secrets. Diffraction from single crystals has revolutionized our knowledge of crystalline matter by providing atomic-scale images of countless samples and leading to landmark achievements in science. However, when crystals of sufficient dimensions cannot be grown, structure can hardly be retrieved using currently available methodologies. This hampers our understanding of the physico-chemical behavior of numerous samples, such as functional organic powders (FOP), hence precluding the design of new materials with tailored properties. Solid-state NMR (SSNMR) has the potential to be the key to access the structure of powders for applications in energy or pharmacy. However, the inherently low sensitivity of NMR constitutes the main barrier to retrieve valuable constraints such as interatomic distances and torsional angles from spin-spin couplings involving rare nuclei (e.g. C-13, N-15) on organic samples at natural isotopic abundance (NA), for which chemical shifts are certainly easier to access but less structurally relevant. The project will capitalize on Dynamic Nuclear Polarization (DNP) to enhance the sensitivity of SSNMR and obtain unique structural constraints on NA FOPs. Specifically: (i) intra and intermolecular distances, torsional/bond angles and H bonds will be measured for the first time via DNP SSNMR; (ii) together with powder X-ray data, these constraints will be integrated within modern computational algorithms to assist the generation of physically meaningful 3D structures with minimized risk of false positives. The protocol will be applied to time-resolved in situ/ex situ investigation of self-assembly to gain control into polymorph production. We will create an integrated experimental/in silico tool that will extend the proficiency of crystallography in de novo structure elucidation of FOPs of increasing complexity, opening new avenues in chemistry and materials science.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["758498"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["LATVIJAS UNIVERSITATE", "VILNIAUS UNIVERSITETAS", "ECOLE NATIONALE SUPERIEURE DE CHIMIE DE MONTPELLIER", "UNIWERSYTET IM. ADAMA MICKIEWICZA W POZNANIU", "FONDAZIONE BRUNO KESSLER", "EESTI MATERJALITEHNOLOOGIATE ARENDUSKESKUSE AS", "BIOSENSOR S.R.L.", "NANOPHARMA AS", "Institute of Biophysics and Cell Engineering, National Academy of Sciences of Belarus"], "EU_Contribution": ["EUR 1 282 500"], "Project_Title": ["Novel 1D photonic metal oxide nanostructures for early stage cancer detection"], "Total_Cost": ["EUR 1 282 500"], "Country": ["Latvia", "Lithuania", "France", "Poland", "Italy", "Estonia", "Italy", "Czech Republic", "Belarus"], "Project_ACR": ["CanBioSe"], "Technology_Description": "The project CanBioSe targeted to strengthen international and intersectoral collaboration, sharing new ideas and knowledge transfer from research to market and vice versa in the field of nanostructured metal oxide optical biosensors for cancer cells detection. Interdisciplinary project research and innovation goals are targeted to develop a new portable tool for early stage cancer detection which can solve on of important health challenges in EU society. One dimensional (1D) polimer nanofibers will be deposited by electrospinning technique. Photonic nanomaterials, based on metal oxide based nanostructures (ZnO, ZnO/Al2O3 nanolaminates, Au/ZnO and ZnO/Au) will coat the 1D nanofibers. Metal oxides and Au nanoparticles will be deposited with Atomic Layer Deposition (ALD) and electrophoresis, respectively. Bioselective layer will be formed by immobilization of specific antibodies on the biosensor surface. Photoluminescence and optical spectroscopy will be used for recording of the biosensor signal. Biosensor testing will be performed on cancer cells (human chronic lymphocyte leukemia (CLL) leucosis and acute lymphoblastic leucosis). The biosensor will be integrated with microfluidic system in order to minimize dimensions and simplify the use of the detection system.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Latvia"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["778157"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["NARODNE POL'NOHOSPODARSKE A POTRAVINARSKE CENTRUM", "INOCURE SRO", "IGV GREENFOOD GGMBH", "NUTRITION SCIENCES NV", "AGRICULTURAL UNIVERSITY OF ATHENS", "BIO BASE EUROPE PILOT PLANT VZW", "SELCUK UNIVERSITESI", "VETERINAERMEDIZINISCHE UNIVERSITAET WIEN"], "EU_Contribution": ["EUR 733 500"], "Project_Title": ["Nanostructured carriers for improved cattle feed"], "Total_Cost": ["EUR 733 500"], "Country": ["Slovakia", "Czech Republic", "Germany", "Belgium", "Greece", "Belgium", "Turkey", "Austria"], "Project_ACR": ["NanoFEED"], "Technology_Description": "The project focuses on a highly actual problem of productivity and quality of livestock production. Livestock production is essential for a sustainable and self-sufficient manufacturing of wide range of products in food industry. One of the key strategies how to enhance competitiveness in the area of food industry is to increase the efficiency of stock raising. Nutritional deficiencies are key factors reducing the efficiency of stock raising, due to high prevalence of serious diseases. Maintaining optimal health of cattle is a key factor for increasing the efficiency of livestock. NanoFEED responds to this factors by nano/microencapsulation approach to advanced core/shell particles with pH sensitive properties.The proposed technology enables encapsulation of diverse active molecules and simplify the protection against degradation in rumen for wide range of active molecules. Nevertheless, due to encapsulation and improved delivery to small intestine, novel active molecules may be used to treat nutritional deficiencies. The process of encapsulation is based on green and biobased methods with minimal carbon footprint helping in development of sustainable bioeconomy. The results of NanoFEED will improve the cattle life expectation, quality of food and will promote more competitive livestock production.", "To": ["2022-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Slovakia"], "Activity": ["Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Other", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["778098"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 1 499 955"], "Project_Title": ["The search for new physics through precision measurements of the CKM angle gamma"], "Total_Cost": ["EUR 1 499 955"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["ONEDEGGAM"], "Technology_Description": "There is a strong conviction that the Standard Model of particle physics is only a low energy approximation to a higher energy theory containing new fundamental particles. For example, it is not possible to explain the large asymmetry between the properties of matter and anti-matter that must exist to create the universe within we live, with the Standard Model that can only accommodate asymmetries orders of magnitude smaller. The theoretical framework that describes these asymmetries is the Cabibbo-Maskawa-Kobayashi (CKM) matrix. ", "To": ["2023-05-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-06-01"], "Project_ID": ["758462"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN", "LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN"], "EU_Contribution": ["EUR 1 499 250"], "Project_Title": ["Pyrazine Signalling in Commensal and Pathogenic Bacteria"], "Total_Cost": ["EUR 1 499 250"], "Country": ["Germany", "Germany"], "Project_ACR": ["PyraSig"], "Technology_Description": "Quorum sensing (QS) is a bacterial cell\u2013cell communication process involving the production, release, and detection of extracellular signal molecules called autoinducers. QS is key to all microbiology as it enables otherwise solitary bacteria to coordinate complex cooperative tasks such as biofilm formation and pathogenesis. Consequently, targeting QS is a promising new concept for antimicrobial therapy. However, for this concept to become reality, we must first identify QS systems in pathogenic bacteria, discover the relevant autoinducers and study the underlying regulatory principles. ", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["758212"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["TECHNISCHE UNIVERSITEIT DELFT", "TECHNISCHE UNIVERSITEIT DELFT"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["A combined in vitro and in vivo approach to dissect biochemical network evolution."], "Total_Cost": ["EUR 1 500 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["EvoCellBio"], "Technology_Description": "How do organisms evolve? I propose to study how biochemical networks reorganize during evolution without compromising fitness. This is a complex problem: firstly, it is hard to know if a mutation increased fitness because this depends on the environment it arose in, which is typically unknown. Secondly, it is hard to find out how adaptive mutations improve fitness, because in cells, all biochemical networks are connected. I will reduce the complexity by two approaches, focused on symmetry-breaking in budding yeast, a functionally conserved process, which is the first step for polarity establishment and essential for proliferation. ", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["758132"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN", "LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN"], "EU_Contribution": ["EUR 1 499 350"], "Project_Title": ["Chromosomal domain formation, compartmentalization and architecture"], "Total_Cost": ["EUR 1 499 350"], "Country": ["Germany", "Germany"], "Project_ACR": ["CHROMDOM"], "Technology_Description": "The three-dimensional organization of chromosomes is necessary for hereditary fidelity and gene regulation. Recent studies have found that eukaryotic interphase chromosomes are spatially organized in compartments, chiefly topologically associated domains (TADs), in a hierarchical order of nested chromatin loops, coining the term \u201cchromosome folding\u201d. TADs are clusters of genes and regulatory elements that are confined to their genomic compartment by spatially constricting their accessible range of action. The folded structure of chromosomes through long-range loops enables mutual interactions of distant genomic loci that otherwise would not be in contact.", "To": ["2023-06-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-07-01"], "Project_ID": ["758124"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET", "KOBENHAVNS UNIVERSITET", "STOCKHOLMS UNIVERSITET"], "EU_Contribution": ["EUR 1 499 531"], "Project_Title": ["Effects of Prenatal Exposure to Acrylamide on Health: Prospective Biomarker-Based Studies"], "Total_Cost": ["EUR 1 499 531"], "Country": ["Denmark", "Denmark", "Sweden"], "Project_ACR": ["CHIPS"], "Technology_Description": "Background: Acrylamide is a chemical formed in many commonly consumed foods and beverages. It is neurotoxic, crosses the placenta and has been associated with restriction of fetal growth in humans. In animals, acrylamide causes heritable mutations, tumors, developmental toxicity, reduced fertility and impaired growth. Therefore, the discovery of acrylamide in food in 2002 raised concern about human health effects worldwide. Still, epidemiological studies are limited and effects on health of prenatal exposure have never been evaluated. ", "To": ["2023-06-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-07-01"], "Project_ID": ["758151"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["INSTITUT CURIE", "INSTITUT CURIE"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Microsatellite Barcoding: reconstructing the family tree of hematopoietic cells"], "Total_Cost": ["EUR 1 500 000"], "Country": ["France", "France"], "Project_ACR": ["MicroBar"], "Technology_Description": "While murine hematopoiesis has been considered as resolved science, recent results using barcoding, which allows the tracing of single cells in vivo, clearly show that the topology of the murine hematopoietic tree needs revisions. In parallel, human hematopoiesis has been overlooked and is widely considered as following the same tree as in mice. To leverage our understanding of normal human hematopoiesis, tools for barcoding in humans are urgently needed. This research program seeks to meet this need by taking advantage of recent developments in next generation sequencing to provide an improved barcoding method for in vivo use in human. Our microsatellite barcoding method exploits the fact that microsatellites in various loci undergo length changes during cell division, to create a natural barcode for each cell, and reconstruct the overall differentiation tree using a phylogenetic algorithm. Our technique, which is highly detailed with respect to current versions of microsatellite barcoding, provides high dimensional characterization of the cells and will allow the inference of important properties such as new phenotypic markers and key molecular regulators. Therefore, we will provide insights into both cell lineage and the molecular mechanisms involved in differentiation. With this method, we will provide the first in vivo description of the human hematopoietic tree and identify new progenitors and key molecular factors involved in human hematopoiesis. This knowledge will allow us to test whether cells with different origins have different functions, a key question in immunology in particular during infection and inflammation, and it will help design ways of therapeutically manipulating the hematopoietic system. More generally it will impact our understanding of stem cell differentiation for which hematopoiesis is used as an exemplar.", "To": ["2023-07-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-08-01"], "Project_ID": ["758170"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITAT AUTONOMA DE BARCELONA", "UNIVERSITAT AUTONOMA DE BARCELONA"], "EU_Contribution": ["EUR 1 418 869"], "Project_Title": ["Paradoxes and Metaphors of Time in Early Universe(s)"], "Total_Cost": ["EUR 1 418 869"], "Country": ["Spain", "Spain"], "Project_ACR": ["PROTEUS"], "Technology_Description": "PROTEUS studies main strategies devised by Western philosophy in representing time in cosmology. It aims at modifying current metaphysics and its relationship with cosmology in the light of recent scientific debates in quantum gravity and quantum cosmology, thereby boosting a new research field in history and philosophy of cosmology. The project is based on two hypotheses: 1) the history of philosophy reveals a guideline that can be traced back to Plato and that characterizes physical and metaphysical approaches to the question of the beginning of the universe in terms of a tension between fundamentality and non-fundamentality of time; 2) there is a conceptual problematic assumption in Western culture and it consists in shaping the problem of the origin of the world as a problem of thinking about the very same conditions of possibility of the origin of a process that is not in time. The project spells out the conceptual roots of current representations of time in quantum gravity and quantum cosmology and highlights the conceptual break that they provide with respect to philosophical concepts of time portrayed in previous systems. PROTEUS explores in detail the notions of time and the paradoxes emerging in the philosophy and cosmology of Plato and Kant and identifies the fundamental characters of emergent time in current quantum gravity theories. In identifying these fundamental features, PROTEUS produces conceptual innovation in metaphysics in such a way that philosophical investigation is complementary to the development of current theories. PROTEUS elaborates alternative argument(s) to anthropic principle, as well as new categories accounting for the notion of \u2018contingent necessity\u2019 of the world. The research team includes members from different backgrounds (philosophy, mathematics and physics) and will promote the application of a new methodology emphasizing the relevance of the history of philosophy and the actual interaction between philosophers and scientists.", "To": ["2023-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["758145"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER", "THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 1 492 424"], "Project_Title": ["Creating Versatile Metallo-Enzyme Environments for Selective C-H Activation Chemistry: Lignocellulose Deconstruction and Beyond"], "Total_Cost": ["EUR 1 492 424"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["enzC-Hem"], "Technology_Description": "The availability of a versatile catalytic platform to precisely target and functionalize individual C-H bonds in complex organic molecules would revolutionize our synthetic strategies, leading to streamlined routes to high value chemicals and supporting the development of a \u2018greener\u2019 chemical industry. Although an impressive range of C-H functionalizations can be achieved with small transition metal complexes, site selectivity is often determined by features of the substrate, and not by the catalyst. A general approach to achieve the more aspirational \u2018catalyst controlled\u2019 transformations requires molecular recognition elements within the catalyst which: a) allow precise substrate orientation and b) can be tuned to alter selectivity. In principle, these requirements could be perfectly addressed by protein catalysts which can be readily adapted via laboratory evolution. However, enzyme engineering strategies are currently limited to Nature\u2019s twenty amino acid alphabet, severely limiting the range of metal co-ordination environments, and thus catalytic activities, that are accessible within proteins. ", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["757991"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITETET I OSLO", "UNIVERSITETET I OSLO"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Mixed-phase clouds and climate (MC2) \u2013 from process-level understanding to large-scale impacts"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Norway", "Norway"], "Project_ACR": ["MC2"], "Technology_Description": "The importance of mixed-phase clouds (i.e. clouds in which liquid and ice may co-exist) for weather and climate has become increasingly evident in recent years. We now know that a majority of the precipitation reaching Earth\u2019s surface originates from mixed-phase clouds, and the way cloud phase changes under global warming has emerged as a critically important climate feedback. Atmospheric aerosols may also have affected climate via mixed-phase clouds, but the magnitude and even sign of this effect is currently unknown. Satellite observations have recently revealed that cloud phase is misrepresented in global climate models (GCMs), suggesting systematic GCM biases in precipitation formation and cloud-climate feedbacks. Such biases give us reason to doubt GCM projections of the climate response to CO2 increases, or to changing atmospheric aerosol loadings. This proposal seeks to address the above issues, through a multi-angle and multi-tool approach: (i) By conducting field measurements of cloud phase at mid- and high latitudes, we seek to identify the small-scale structure of mixed-phase clouds. (ii) Large-eddy simulations will then be employed to identify the underlying physics responsible for the observed structures, and the field measurements will provide case studies for regional cloud-resolving modelling in order to test and revise state-of-the-art cloud microphysics parameterizations. (iii) GCMs, with revised microphysics parameterizations, will be confronted with cloud phase constraints available from space. (iv) Finally, the same GCMs will be used to re-evaluate the climate impact of mixed-phase clouds in terms of their contribution to climate forcings and feedbacks. Through this synergistic combination of tools for a multi-scale study of mixed-phase clouds, the proposed research has the potential to bring the field of climate science forward, from improved process-level understanding at small scales, to better climate change predictions on the global scale.", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["758005"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITAET KLAGENFURT", "UNIVERSITAET KLAGENFURT"], "EU_Contribution": ["EUR 1 401 941"], "Project_Title": ["Hidden Emissions of Forest Transitions: GHG effects of socio-metabolic processes reducingpressures on forests"], "Total_Cost": ["EUR 1 401 941"], "Country": ["Austria", "Austria"], "Project_ACR": ["HEFT"], "Technology_Description": "A forest transition, i.e. forest expansion after a long period of deforestation, has occurred in many, mostly industrialized countries. Forest transitions have recently resulted in declining rates of global net deforestation and contributed to carbon (C) sinks in terrestrial ecosystems. Studies have shown the concurrence of forest transitions and industrialization processes, but the systemic links between forest transitions, their underlying socio-metabolic processes and associated greenhouse gas (GHG) emissions have been neither systematically explored nor quantified.", "To": ["2023-03-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-04-01"], "Project_ID": ["757995"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["TECHNISCHE UNIVERSITEIT EINDHOVEN", "TECHNISCHE UNIVERSITEIT EINDHOVEN"], "EU_Contribution": ["EUR 1 998 504,75"], "Project_Title": ["Multi-perspective Ultrasound Strain Imaging & Elastography"], "Total_Cost": ["EUR 1 998 504,75"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["MUSE"], "Technology_Description": "Ultrasound (US) is the modality of choice for imaging and functional measurements of the cardiovascular system due to its high spatial and temporal resolution. In recent years, the use of US has been on the rise owing to huge advancements in acquisition speed and resolution. Nevertheless, because of physical constraints, several issues \u2014limited field-of-view, refraction, resolution and, contrast anisotropy\u2014 cannot be resolved using a single probe. ", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["757958"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN", "OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN"], "EU_Contribution": ["EUR 1 499 992"], "Project_Title": ["\u2018Challenging Time(s)\u2019 \u2013 A New Approach to Written Sources for Ancient Egyptian Chronology"], "Total_Cost": ["EUR 1 499 992"], "Country": ["Austria", "Austria"], "Project_ACR": ["CT"], "Technology_Description": "The chronology of ancient Egypt is a golden thread for the memory of early civilisation. It is not only the scaffolding of four millennia of Egyptian history, but also one of the pillars of the chronology of the entire ancient Near East and eastern Mediterranean. The basic division of Egyptian history into 31 dynasties was introduced by Manetho, an Egyptian historian (c. 280 BC) writing in Greek for the Ptolemaic kings. Despite the fact that this scheme was adopted by Egyptologists 200 years ago and remains in use until today, there has never been an in-depth analysis of Manetho\u2019s kinglist and of the names in it. Until now, identifying the Greek renderings of royal names with their hieroglyphic counterparts was more or less educated guesswork. It is thus essential to introduce the principles of textual criticism, to evaluate royal names on a firm linguistic basis and to provide for the first time ever an Egyptological commentary on Manetho\u2019s kinglist. Just like Manetho did long ago, now it is necessary to gather all inscriptional evidence on Egyptian history: dated inscriptions, biographic and prosopographic data of royalty and commoners, genuine Egyptian kinglists and annals. These data must be critically evaluated in context, their assignment to specific reigns must be reconsidered, and genealogies and sequences of officials must be reviewed. The results are not only important for Egyptian historical chronology and for our understanding of the Egyptian perception of history, but also for the interpretation of chronological data gained from archaeological excavations (material culture) and sciences (14C dates, which are interpreted on the basis of historical chronology, e.g., via \u2018Bayesian modelling\u2019). The applicant has already shown the significance of this approach in pilot studies on the pyramid age. Further work in cooperation with international specialists will thus shed new light on ancient sources in order to determine the chronology of early civilisation.", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Austria"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-03-01"], "Project_ID": ["757951"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 436 330"], "Project_Title": ["SOot in TUrbulent Flames: a new look at soot production processes in turbulent flames leading to novel models for predictive large eddy simulations"], "Total_Cost": ["EUR 1 436 330"], "Country": ["France", "France"], "Project_ACR": ["SOTUF"], "Technology_Description": "Many practical systems emit soot into the atmosphere as a result of incomplete combustion of hydrocarbons. This pollutant emission is characterized by a distribution of solid carbon particles with different sizes and shapes, which have negative effects on human health and environment. Controlling such emission represents a societal issue and an industrial challenge that require a deep understanding of the intricate processes underlying soot production in the turbulent flames that generally characterize practical systems. In this context, progress in numerical simulations is essential to the successful design of low-emission combustion systems. Unfortunately, the Large-Eddy Simultations (LES) approach, which has successfully demonstrated its capacity to represent gaseous turbulent combustion processes, is far from being predictive for soot emission. Indeed, soot production in turbulent flames is a complex process which is not easy to be represented with the classical LES strategy: the long time scales and the broad range of length scales place soot processes outside the usual scale ranges of LES subgrid models. In this context, the goal of the present project is to provide new insights on the processes governing soot production in turbulent flames to develop novel LES models, encompassing the state-of-art and allowing reliable predictions of soot in turbulent flames. These objectives will be achieved by: (1) characterizing the turbulence-flame-soot coupling from novel well-controlled experiments employing advanced space and time resolved optical diagnostics; (2) developing new subgrid models based on information extracted from experiments and high-fidelity simulations; (3) validating and applying the developed LES modeling strategy on complex systems. The research results are expected to drastically improve the prediction of soot production in industrial configurations, helping to design new low-emission systems with notably reduced soot levels.", "To": ["2023-05-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-06-01"], "Project_ID": ["757912"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["CENTRE INTERNATIONAL DE RECHERCHE AUX FRONTIERES DE LA CHIMIE", "CENTRE INTERNATIONAL DE RECHERCHE AUX FRONTIERES DE LA CHIMIE"], "EU_Contribution": ["EUR 1 762 488"], "Project_Title": ["Life-like Supramolecular Materials based on Reaction Cycles with Designed Feedback"], "Total_Cost": ["EUR 1 762 488"], "Country": ["France", "France"], "Project_ACR": ["Life-Cycle"], "Technology_Description": "This \u201cLife-Cycle\u201d ERC proposal aims to develop a new class of artificial supramolecular materials that are kept in sustained non-equilibrium states by continuous dissipation of chemical fuels. Supramolecular polymers in current artificial materials stick together through weak reversible bonds that can be exchange by thermal energy. In contrast, natural supramolecular polymers such as those in the cytoskeletal network use chemical fuels such as adenosine triphosphate (ATP) to achieve an incredible adaptivity, motility, growth, and response to external inputs. Development of chemically fueled artificial supramolecular polymers should therefore lead to more life-like materials that could perform functions so far reserved only for living beings. ", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["757910"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Atmospheres across the Universe"], "Total_Cost": ["EUR 1 500 000"], "Country": ["France", "France"], "Project_ACR": ["ATMO"], "Technology_Description": "Which molecules are present in the atmosphere of exoplanets? What are their mass, radius and age? Do they have clouds, convection (atmospheric turbulence), fingering convection, or a circulation induced by irradiation? These questions are fundamental in exoplanetology in order to study issues such as planet formation and exoplanet habitability.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-02-01"], "Project_ID": ["757858"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN", "KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN"], "EU_Contribution": ["EUR 1 490 529"], "Project_Title": ["A molecular approach to treat diabetes mellitus onset dependent coronaropathy"], "Total_Cost": ["EUR 1 490 529"], "Country": ["Germany", "Germany"], "Project_ACR": ["DIAMONDCOR"], "Technology_Description": "In Europe, 59 million patients suffer from diabetes mellitus with health costs of 142 billion Euros per year. As one of the most challenging consequences, diabetes inflicts cardiovascular disease leading to cardiomyopathy and cardiac death. A global, current aim lies in preventing cardiac complications in patients with diabetes mellitus.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["758087"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITAT WIEN", "UNIVERSITAT WIEN"], "EU_Contribution": ["EUR 1 257 973"], "Project_Title": ["Islamic architecture and Orientalizing style in Habsburg Bosnia, 1878-1918"], "Total_Cost": ["EUR 1 257 973"], "Country": ["Austria", "Austria"], "Project_ACR": ["THEKAISERSMOSQUES"], "Technology_Description": "The project highlights a grossly understudied experiment at the intersection of nineteenth-century European and Islamic architectural histories. It draws attention to a significant body of buildings designed by architects trained in Central Europe for use by Muslims in Habsburg-ruled Bosnia-Herzegovina (1878-1918). These buildings, many of which mosques, largely draw upon a traditional Islamic formal and functional typology. The composition and decoration of their facades, however, is the product of nineteenth-century Historicist conduct. Quoted are elements from assorted Islamic artistic heritages, with prominence given to Cairo and Andalusia. In Bosnia, many of these buildings were misinterpreted as mere renovations of Ottoman edifices, as is indeed declared on several inscriptions. However, this information generally appears to pertain to the institutions accommodated in these buildings rather than to their present form and architecture. ", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["758099"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["ECOLE NATIONALE DES PONTS ET CHAUSSEES", "ECOLE NATIONALE DES PONTS ET CHAUSSEES"], "EU_Contribution": ["EUR 1 499 999"], "Project_Title": ["Controlling earthQuakes"], "Total_Cost": ["EUR 1 499 999"], "Country": ["France", "France"], "Project_ACR": ["CoQuake"], "Technology_Description": "According to the Centre for Research on the Epidemiology of Disasters (CRED), earthquakes are responsible for more than half of the total human losses due to natural disasters from 1994 to 2003. There is no doubt that earthquakes are lethal and costly. CoQuake proposes an alternative, ground-breaking approach for avoiding catastrophic earthquakes by inducing them at a lower energetic level. Earthquakes are a natural phenomenon that we cannot avoid, but \u2013for the first time\u2013 in CoQuake I will show that it is possible to control them, hence reducing the seismic risk, fatalities and economic cost. CoQuake goes beyond the state-of-the-art by proposing an innovative methodology for investigating the effect and the controllability of various stimulating techniques that can reactivate seismic faults. It involves large-scale, accurate simulations of fault systems based on constitutive laws derived from micromechanical, grain-by-grain simulations under Thermo-Hydro-Chemo-Mechanical couplings (THMC), which are not calibrated on the basis of ad-hoc empirical and inaccurate constitutive laws. A pioneer experimental research programme and the design and construction of a new apparatus of metric scale, will demonstrate CoQuake\u2019s proof-of-principle and it will help to explore the transition from aseismic to seismic slip. CoQuake is an interdisciplinary project as it takes knowledge from various fields of engineering, computational mechanics, geomechanics, mathematics and geophysics. CoQuake opens a new field and new line of research in earthquake mechanics and engineering, with a direct impact on humanity and science.", "To": ["2023-05-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-06-01"], "Project_ID": ["757848"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITAT POLITECNICA DE CATALUNYA", "UNIVERSITAT POLITECNICA DE CATALUNYA"], "EU_Contribution": ["EUR 1 100 347,50"], "Project_Title": ["Instabilities and homoclinic phenomena in Hamiltonian systems"], "Total_Cost": ["EUR 1 100 347,50"], "Country": ["Spain", "Spain"], "Project_ACR": ["HamInstab"], "Technology_Description": "A fundamental problem in the study of dynamical systems is to ascertain whether the effect of a perturbation on an integrable Hamiltonian system accumulates over time and leads to a large effect (instability) or it averages out (stability). Instabilities in nearly integrable systems, usually called Arnold diffusion, take place along resonances and by means of a", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["757802"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["KAROLINSKA INSTITUTET", "KAROLINSKA INSTITUTET"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["A TRranslational approach to Identify Biomarkers for Asthma and Lung function impairment"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["TRIBAL"], "Technology_Description": "Asthma is a chronic inflammatory disease of the airways that cause symptoms like wheezing and breathlessness. In children, asthma is the most common chronic disease and according to the WHO, more than 300 million people are affected globally. There is no curative treatment available. Persistence of childhood asthma into adult life is associated with lung function impairment and increased risk of chronic obstructive pulmonary disease, COPD. Evidence is now emerging that adult diseases, like COPD, may have their origin early in life. However, there are no established biomarkers that can accurately monitor asthma progression or predict development of COPD in adults. In this TRIBAL project, I will capitalize on rich longitudinal data and repeated bio-sampling from the Swedish BAMSE study, a world-leading population-based birth cohort of 4,089 participants with a new 24-year follow-up starting in 2017. A key aim with the new follow-up is to identify young adults in their 20s with persistent asthma and pre-stage COPD by advanced lung function assessment that includes bronchodilator and nitrogen washout tests. In TRIBAL, the unique setup is deep phenotyping of these patients describing different aspects of the respiratory system, as well as molecular characteristics of relevant bio-samples and cells. Disease-related biomarkers and involved mechanisms, from gene to protein, will be identified from early childhood to adulthood. Both the innate and the adapted immune system with detailed cell characterization will be explored in relation to exposure and disease development. Specifically, with this novel approach I will address the time point during childhood when disease processes related to persistent asthma and pre-stage COPD were initiated. The ultimate goal in TRIBAL is to provide new knowledge for targeted preventive efforts in children at risk of adult chronic lung disease, and to identify potential targets for new asthma and COPD drugs.", "To": ["2022-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["757919"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET", "KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 1 427 741"], "Project_Title": ["Eco-physiological tradeoffs with crop domestication: have farming ants cracked the code?"], "Total_Cost": ["EUR 1 427 741"], "Country": ["Denmark", "Denmark"], "Project_ACR": ["ELEVATE"], "Technology_Description": "Domesticated crops hardly resemble their wild ancestors, and often trade higher yield in artificially optimized conditions for lower performance in fluctuating environments. Leafcutter ants (genus Atta) provide fascinating parallels with human farmers, harvesting fresh vegetation used as compost to produce domesticated fungal crops that feed massive societies with millions of workers. However, while human agricultural systems are imperiled by rapid global changes, leafcutter ants have managed to grow one type of cultivar from Texas to Argentina, thriving across extreme rainfall and temperature gradients and across diverse climates over millions of years. However, the eco-physiological mechanisms governing this farming resiliency are poorly understood.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["757810"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["TECHNISCHE UNIVERSITEIT EINDHOVEN", "TECHNISCHE UNIVERSITEIT EINDHOVEN"], "EU_Contribution": ["EUR 1 497 982"], "Project_Title": ["Fundamentals of the Nonlinear Optical Channel"], "Total_Cost": ["EUR 1 497 982"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["FUN-NOTCH"], "Technology_Description": "Fibre optics are critical infrastructure for society because they carry nearly all the global Internet traffic. For a long time, optical fibre systems were thought to have infinite information-carrying capabilities. With current traffic demands growing by a factor between 10 and 100 every decade, however, this is no longer the case. In fact, it is currently unknown if the installed optical infrastructure will manage to cope with these demands in the future, or if we will face the so-called \"capacity crunch\".", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["757791"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN", "KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN"], "EU_Contribution": ["EUR 1 499 989"], "Project_Title": ["Deconstruction of a neural circuit for working memory: hubs, coding mechanisms, and signal routing"], "Total_Cost": ["EUR 1 499 989"], "Country": ["Germany", "Germany"], "Project_ACR": ["MEMCIRCUIT"], "Technology_Description": "Working memory is the basis of cognition. It allows behaviour to be governed by internal goals rather than by reflexive stimulus-response mappings. The neural mechanisms of memory maintenance are heavily contested. Animal electrophysiology studies suggest a pivotal role of persistent spiking activity in single neurons of the prefrontal cortex, whereas human neuroimaging points to sub-threshold synaptic activity distributed across sensory cortex. This double dissociation of storage mechanisms and storage sites could result from the comparison of different recording methods, which measure distinct neuronal signals. Alternatively, there might be a fundamental difference between humans and animals. My key objective is to formulate general principles of working memory coding at the cellular and circuit level by integrating across previously disconnected lines of research. I will address two central questions. First, where and how is the memorized information stored? I will use an innovative approach to record large-scale single-unit activity from a cognitive (prefrontal) and a sensory (auditory) region in awake neurosurgical patients and directly compare the data to recordings from mice performing the same auditory working memory task. This will allow me to determine whether the mnemonic fingerprints are species-specific or shared across humans and rodents. Second, what neural pathways support the flow of information during working memory? Using the animal model, I will disrupt cross-regional interactions in the memory network with millisecond-precise, projection-specific optogenetic tools in order to dissect the contribution of each hub to memory storage and memory access. This project provides an unprecedented one-to-one matching of behavioural tasks and recording methods with single-cell and split-second resolution in humans and rodents. It represents a major step forward in understanding the cellular and circuit basis of a critical cognitive brain function.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["758032"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITE DE LIEGE", "UNIVERSITE DE LIEGE"], "EU_Contribution": ["EUR 1 499 125"], "Project_Title": ["To nap or not to nap? Why napping habits interfere with cognitive fitness in ageing"], "Total_Cost": ["EUR 1 499 125"], "Country": ["Belgium", "Belgium"], "Project_ACR": ["COGNAP"], "Technology_Description": "All of us know of individuals who remain cognitively sharp at an advanced age. Identifying novel factors which associate with inter-individual variability in -and can be considered protective for- cognitive decline is a promising area in ageing research. Considering its strong implication in neuroprotective function, COGNAP predicts that variability in circadian rhythmicity explains a significant part of the age-related changes in human cognition. Circadian rhythms -one of the most fundamental processes of living organisms- are present throughout the nervous system and act on cognitive brain function. Circadian rhythms shape the temporal organization of sleep and wakefulness to achieve human diurnality, characterized by a consolidated bout of sleep during night-time and a continuous period of wakefulness during the day. Of prime importance is that the temporal organization of sleep and wakefulness evolves throughout the adult lifespan, leading to higher sleep-wake fragmentation with ageing. The increasing occurrence of daytime napping is the most visible manifestation of this fragmentation. Contrary to the common belief, napping stands as a health risk factor in seniors in epidemiological data. I posit that chronic napping in older people primarily reflects circadian disruption. Based on my preliminary findings, I predict that this disruption will lead to lower cognitive fitness. I further hypothesise that a re-stabilization of circadian sleep-wake organization through a nap prevention intervention will reduce age-related cognitive decline. Characterizing the link between cognitive ageing and the temporal distribution of sleep and wakefulness will not only bring ground-breaking advances at the scientific level, but is also timely in the ageing society. Cognitive decline, as well as inadequately timed sleep, represent dominant determinants of the health span of our fast ageing population and easy implementable intervention programs are urgently needed.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["757763"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE", "INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE"], "EU_Contribution": ["EUR 1 497 045"], "Project_Title": ["Accelerating Neuroscience Research by Unifying Knowledge Representation and Analysis Through a Domain Specific Language"], "Total_Cost": ["EUR 1 497 045"], "Country": ["France", "France"], "Project_ACR": ["NeuroLang"], "Technology_Description": "Neuroscience is at an inflection point. The 150-year old cortical specialization paradigm, in which cortical brain areas have a distinct set of functions, is experiencing an unprecedented momentum with over 1000 articles being published every year. However, this paradigm is reaching its limits. Recent studies show that current approaches to atlas brain areas, like relative location, cellular population type, or connectivity, are not enough on their own to characterize a cortical area and its function unequivocally. This hinders the reproducibility and advancement of neuroscience. ", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-03-01"], "Project_ID": ["757672"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 499 901"], "Project_Title": ["Structural Biology of Exopolysaccharide Secretion in Bacterial Biofilms"], "Total_Cost": ["EUR 1 499 901"], "Country": ["France", "France"], "Project_ACR": ["BioMatrix"], "Technology_Description": "Bacterial biofilm formation is a paramount developmental process in both Gram-positive and Gram-negative species and in many pathogens has been associated with processes of horizontal gene transfer, antibiotic resistance development and pathogen persistence. Bacterial biofilms are collaborative sessile macrocolonies embedded in complex extracellular matrix that secures both mechanical resistance and a medium for intercellular exchange. ", "To": ["2023-07-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-08-01"], "Project_ID": ["757507"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON", "UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["The Mechanisms and Dynamics Controlling Cycles of Lymph Node Expansion"], "Total_Cost": ["EUR 1 500 000"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["LNEXPANDS"], "Technology_Description": "Lymph node swelling is a classical hallmark of immunity. This expansion is observed by doctors, researchers and patients, yet as obvious as this process is, our understanding of the remodelling mechanisms involved are in their infancy. Lymph node remodelling is rapid and yet completely reversible, occurring countless times throughout our lifetimes. The purpose of this proposal is to understand how lymph node remodelling occurs and is resolved, repeatedly; to understand immunity in a whole organ context.", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["757573"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITY OF LEEDS", "UNIVERSITY OF LEEDS"], "EU_Contribution": ["EUR 1 499 840"], "Project_Title": ["Data Assimilation for Agent-Based Models: Applications to Civil Emergencies"], "Total_Cost": ["EUR 1 499 840"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["DUST"], "Technology_Description": "Civil emergencies such as flooding, terrorist attacks, fire, etc., can have devastating impacts on people, infrastructure, and economies. Knowing how to best respond to an emergency can be extremely difficult because building a clear picture of the emerging situation is challenging with the limited data and modelling capabilities that are available. Agent-based modelling (ABM) is a field that excels in its ability to simulate human systems and has therefore become a popular tool for simulating disasters and for modelling strategies that are aimed at mitigating developing problems. However, the field suffers from a serious drawback: models are not able to incorporate up-to-date data (e.g. social media, mobile telephone use, public transport records, etc.). Instead they are initialised with historical data and therefore their forecasts diverge rapidly from reality.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["757455"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["DANMARKS TEKNISKE UNIVERSITET", "DANMARKS TEKNISKE UNIVERSITET"], "EU_Contribution": ["EUR 1 463 805"], "Project_Title": ["Measuring with no tape"], "Total_Cost": ["EUR 1 463 805"], "Country": ["Denmark", "Denmark"], "Project_ACR": ["NoTape"], "Technology_Description": "Society generates increasing amounts of data, which is both a resource and a challenge. The data reveal new insights that may potentially improve our livelihood, but their quantity renders such insights difficult to find. Machine learning techniques sift through the data looking for statistical patterns of interest to a given task. Due to an exponential growth in available data, these techniques enable us to automate difficult decisions, such as those needed for personalized medicine and self-driving cars.", "To": ["2022-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["757360"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["KARLSRUHER INSTITUT FUER TECHNOLOGIE", "KARLSRUHER INSTITUT FUER TECHNOLOGIE"], "EU_Contribution": ["EUR 1 499 920"], "Project_Title": ["Blood and bone \u2013 conjoined twins in health and disease: bone marrow analogs for hematological and musculoskeletal diseases"], "Total_Cost": ["EUR 1 499 920"], "Country": ["Germany", "Germany"], "Project_ACR": ["bloodANDbone"], "Technology_Description": "Blood and bone are closely intertwined. Their intrinsic regenerative capacities are disturbed in many hematological and musculoskeletal diseases. Re-establishing the regenerative potential is the key to cure these diseases by regenerative medicine. Multipotent stem cells of both tissues \u2013 hematopoietic stem cells (HSCs) for blood and mesenchymal stem/stromal (MSCs) for bone \u2013 are the basis for their regenerative capacity. While it is well established that HSCs are influenced by the bone marrow in their natural environment including MSCs and their progeny, surprisingly little attention has been paid to the reciprocal relationship. The hypothesis of the current proposal is that only when taking both tissues and their mutual crosstalk into account, we will be able to understand how the regenerative potential of blood and bone is impaired in disease and how it can be re-established with novel treatment strategies. For this purpose we need to understand the early events of disease onset and progression. Due to the limitations of such studies in human beings and animals, I propose to develop human in vitro models of healthy bone marrow, which can be induced to develop hematological and musculoskeletal diseases with high incidence, namely leukemia, multiple myeloma and bone metastasis. Previously my team and I developed a simplified bone marrow analog that bases on macroporous, cell-laden biomaterials with tunable physical, biochemical and biological properties. This versatility will enable us to create biomimetic human in vitro models of the human bone marrow in health and disease, which are ground-breaking in their applicability to investigate how the regenerative balance of bone marrow is maintained in health and disturbed in the different kinds of diseases \u2013 a prerequisite to develop novel regenerative treatments \u2013 as well as their scalability and thus suitability as in vitro test systems for screening of novel drugs or treatments.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["757490"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["SERVICIO MADRILENO DE SALUD", "SERVICIO MADRILENO DE SALUD"], "EU_Contribution": ["EUR 1 497 314"], "Project_Title": ["Understanding the evolution of plasmid-mediated antibiotic resistance in real life scenarios"], "Total_Cost": ["EUR 1 497 314"], "Country": ["Spain", "Spain"], "Project_ACR": ["PLASREVOLUTION"], "Technology_Description": "Antibiotics are essential tools in modern medicine and are indispensable not only for the treatment of infectious diseases but also to support other key interventions such as surgery and cancer chemotherapy. However, the extensive and inappropriate use of antibiotics has fuelled the spread of resistance mechanisms in pathogenic bacteria, leading to the dawn of a post-antibiotic era. Plasmids play a pivotal role in the evolution of antibiotic resistance (AR) because they drive the horizontal transfer of resistance genes between pathogenic bacteria by conjugation. Some of these plasmid-bacterium associations become particularly successful, creating superbugs that spread uncontrollably in clinical settings. The rise of these clones is mainly constricted because plasmids entail a fitness cost when they arrive in a new bacterial host. This cost can be subsequently alleviated through compensatory adaptation during plasmid-bacterium coevolution. Despite the importance of this cost-compensation dynamic in the evolution of plasmid-mediated AR, it remains completely unexplored in clinical contexts. In this project I plan to bridge this gap by exploring the genetic basis underlying the evolution of plasmid-mediated AR in clinically relevant scenarios. We will study, for the first time, the intra-patient transmission, fitness cost and adaptation of AR plasmids in the gut microbiome of hospitalized patients (obj. 1). We will analyse the molecular mechanisms that determine the success of AR plasmids and bacterial clone associations (obj. 2). Finally, we will develop new technology to test how antibiotic treatments affect AR plasmids dynamics in the gut microbiome at an unprecedentedly high-resolution (obj. 3). This ground-breaking project will allow a new understanding of the evolution of plasmid-mediated AR in real life, opening new research avenues and providing a major step towards meeting one of the central challenges facing our society: controlling the spread of AR.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Spain"], "Activity": ["Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2018-02-01"], "Project_ID": ["757440"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["NPL MANAGEMENT LIMITED", "NPL MANAGEMENT LIMITED"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Interaction and Symmetry Breaking of Counterpropagating Light"], "Total_Cost": ["EUR 1 500 000"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["CounterLIGHT"], "Technology_Description": "Light is generally expected to travel through media independent of its direction. Exceptions can be achieved eg. through polarization changes induced by magnetic fields (known as the Faraday effect) together with polarization-sensitive birefringent materials. However, light can also be influenced by the presence of a counterpropagating light wave. We have recently shown that this leads to the surprising consequence that light sent into tiny glass rings (microresonators) can only propagate in one direction, clockwise or counterclockwise, but not in both directions simultaneously. When sending exactly the same state of light (same power and polarization) into a microresonator, nonlinear interaction induces a spontaneous symmetry breaking in the propagation of light. In this proposal we plan to investigate the fundamental physics and a variety of ground-breaking applications of this effect. In one proposed application, this effect will be used for optical nonreciprocity and the realization of optical diodes in integrated photonic circuits that do not rely on magnetic fields (an important key element in integrated photonics). In another proposed experiment we plan to use the spontaneous symmetry breaking to demonstrate microresonator-based optical gyroscopes that have the potential to beat state-of-the-art sensors in both size and sensitivity. Additional research projects include experiments with all-optical logic gates, photonic memories, and near field sensors based on counterpropagating light states. Finally, we plan to demonstrate a microresonator-based system for the generation of dual-optical frequency combs that can be used for real-time precision spectroscopy in future lab-on-a-chip applications. On the fundamental physics side, our experiments investigate the interaction of counterpropagating light in a system with periodic boundary conditions. The fundamental nature of this system has the potential to impact other fields of science far beyond optical physics.", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-03-01"], "Project_ID": ["756966"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITY OF GLASGOW", "UNIVERSITY OF GLASGOW"], "EU_Contribution": ["EUR 1 422 818"], "Project_Title": ["Work on Demand: Contracting for Work in a Changing Economy"], "Total_Cost": ["EUR 1 422 818"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["WorkOD"], "Technology_Description": "Labour law as a scholarly discipline is widely believed to be in crisis. Since the time of its birth, both the nature of working relationships and the context within which they are formed and regulated have changed significantly. The difficulty for scholars is that old concepts don\u2019t perform the function anymore of making sense of the field. Old arguments about the need to protect workers\u2019 interests are met with counterarguments, informed by neoclassical economics, that protective measures inhibit economic growth and increase unemployment. ", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["757395"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["DANMARKS TEKNISKE UNIVERSITET", "DANMARKS TEKNISKE UNIVERSITET"], "EU_Contribution": ["EUR 1 423 357,50"], "Project_Title": ["Deciphering the transport mechanisms of small xenobiotic molecules in synthetic yeast cell factories"], "Total_Cost": ["EUR 1 423 357,50"], "Country": ["Denmark", "Denmark"], "Project_ACR": ["YEAST-TRANS"], "Technology_Description": "Industrial biotechnology employs synthetic cell factories to create bulk and fine chemicals and fuels from renewable resources, laying the basis for the future bio-based economy. The major part of the wanted bio-based chemicals are not native to the host cell, such as yeast, i.e. they are xenobiotic. Some xenobiotic compounds are readily secreted by synthetic cells, some are poorly secreted and some are not secreted at all, but how does this transport occur? Or why does it not occur? These fundamental questions remain to be answered and this will have great implications on industrial biotechnology, because improved secretion would bring down the production costs and enable the emergence of novel bio-based products. ", "To": ["2022-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["757384"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES"], "EU_Contribution": ["EUR 1 499 094"], "Project_Title": ["Energetics of natural turbulent flows: the impact of waves and radiation."], "Total_Cost": ["EUR 1 499 094"], "Country": ["France", "France"], "Project_ACR": ["FLAVE"], "Technology_Description": "Turbulence in natural flows is an outstanding challenge with key implications for the energetics of planets, stars, oceans, and the Earth\u2019s climate system. Such natural flows interact with waves, radiation or a combination thereof: surface waves and solar radiation on oceans and lakes, bulk waves and radiation inside the rapidly rotating and electrically conducting solar interior, etc. Standard simplified models often discard waves, radiation, or both, with dramatic consequences for the energy budget of natural flows: geostrophic models neglect waves, and Rayleigh-B\u00e9nard thermal convection considers heat diffusively injected through a solid boundary, in strong contrast with radiative heating. The purpose of the present multidisciplinary project is to develop a consistent and coupled description of natural flows interacting with waves and radiation, to properly assess their energy budget:", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-03-01"], "Project_ID": ["757239"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["ERASMUS UNIVERSITEIT ROTTERDAM", "ERASMUS UNIVERSITEIT ROTTERDAM"], "EU_Contribution": ["EUR 1 261 246"], "Project_Title": ["The role of the father in child development and the intergenerational transmission of inequality: Linking sociological stratification questions to developmental psychology research"], "Total_Cost": ["EUR 1 261 246"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["FATHERCHILD"], "Technology_Description": "The key objective of my FATHERCHILD project is to provide novel insights into the questions whether, why, and in what ways, fathers influence their children\u2019s social, behavioral, emotional, and cognitive outcomes. More specifically, this project investigates how inequalities in child outcomes develop through fathers\u2019 parenting practices across childhood and adolescence, and how context may buffer or strengthen fathers\u2019 role in this development of inequalities. The idea underlying the proposed research is that much can be learned about fathers\u2019 role in child outcomes by linking sociological stratification questions to developmental psychology research on father involvement. The relevance of the current project is apparent: inequality is rising all across Europe, people are increasingly relying on their families to get by, and father involvement has become more polarized according to fathers\u2019 socioeconomic position over the decades. ", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["757210"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["THE UNIVERSITY OF EDINBURGH", "THE UNIVERSITY OF EDINBURGH", "UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 1 942 471"], "Project_Title": ["Tropical Forest Degradation Experiment"], "Total_Cost": ["EUR 1 942 471"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom"], "Project_ACR": ["FODEX"], "Technology_Description": "We know how to map tropical forest biomass using an array of satellite and aircraft sensors with reasonable accuracy (\u00b115-40 %). However, we do not know how to map biomass change. Simply differencing existing biomass maps produces noisy and biased results, with confidence intervals unknowable using existing static field plots. Thus the potential for using plentiful free satellite data for biomass change mapping is being wasted.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["757526"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["THE HEBREW UNIVERSITY OF JERUSALEM", "THE HEBREW UNIVERSITY OF JERUSALEM"], "EU_Contribution": ["EUR 1 499 875"], "Project_Title": ["Mechanical Targeting as an Integrative Approach for Personalized Nanomedicine"], "Total_Cost": ["EUR 1 499 875"], "Country": ["Israel", "Israel"], "Project_ACR": ["MTrix"], "Technology_Description": "The ability to direct drug delivery to specific tissues is a central challenge in treating diseases as it determines the balance between drug selectivity and toxicity. Clinical drug failures, commonly due to safety issues or poor efficacy, are extremely costly to the pharmaceutical industry. In light of this, there is a global effort to develop Targeted Drug Delivery Systems (DDS) and Nanomedicine-based drugs to increase the therapeutic efficacy of a drug while substantially reducing its off-target exposure. In oncology, this issue is critical since chemotherapies have poor selectivity, thus causing severe side effects due to undesired systemic exposure. However, the enormous heterogeneity and dynamic nature of tumors makes it extremely challenging to identify universal target molecules. In this ERC I introduce a novel concept according to which the specificity of DDS can be dramatically enhanced by tuning the physical parameters of DDS based on mechanical cues of target and non-target cells. In many cancers, it is well-established that the flexibility and deformability of cells are correlated with their metastatic potential. This leads to our hypothesis that the enhanced deformability of cancer cells allows them to engulf and uptake particles whose internalization requires massive shape change, unlike the stiffer and normal cells. The rationale of the proposed study is that by considering physical parameters of cells, the mechanical properties of DDS can be tuned to achieve selective uptake. We thus propose to develop tools for rational design of DDS for personalized nanomedicine that will use simple tests performed on a patient\u2019s own cells. This is the basis of our visionary Mechanical Targeting (MT) scheme, a crosstalk between experimental and computational models, for drug specificity. Accordingly, this ERC is expected to yield breakthroughs, both conceptual and technical.", "To": ["2022-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["756762"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["HEINRICH-HEINE-UNIVERSITAET DUESSELDORF", "HEINRICH-HEINE-UNIVERSITAET DUESSELDORF"], "EU_Contribution": ["EUR 1 494 058,75"], "Project_Title": ["The Motor Representation of Sensory Experience"], "Total_Cost": ["EUR 1 494 058,75"], "Country": ["Germany", "Germany"], "Project_ACR": ["moreSense"], "Technology_Description": "How do we experience the visual world around us? The traditional view holds that the retinal input is analyzed to reconstruct an internal image that generates our perceptual experience. However, a general theory of how visual features are experienced in space and time is lacking. The fundamental claim of this grant proposal is that only motor knowledge - i.e. the way we interact with the world - establishes the underlying metric of space and time perception. In this model view, the spatial and temporal structure of perception is embedded in the processing of neural motor maps. The project moreSense has four major objectives: First, it will unravel how neural motor maps provide the metric for the experience of visual space. It will be hypothesised that there is no central neural map of space or time but a weighted contribution of all maps. Novel experimental techniques are required to uncover the motor basis of perception, which are available by recent developments in head-mounted displays and online motion tracking. Second, it will provide a general understanding of time perception being implicitly coded in movement plans to objects in space. Third, results from the first two objectives will be applied to the long-standing mystery of visual stability and continuity across movements. A bayesian model, supported by quantitative measurements, will demonstrate how information combination from the various motor maps leads naturally to stable and continuous perception. Fourth, this new theory of space and time perception will be investigated in patients suffering from a breakdown of space perception. The results will establish causal evidence that space and time perception are generated by processing in motor maps. New rehabilitation procedures will be developed to re-establish spatial perception in these patients. The experiments in this grant proposal will unravel the fundamental spatiotemporal structure of perception which organizes our sensory experience.", "To": ["2023-03-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-04-01"], "Project_ID": ["757184"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY", "TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Memristive In-Memory Processing System"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Israel", "Israel"], "Project_ACR": ["Real-PIM-System"], "Technology_Description": "Our project aims to develop a new computer architecture that enables true in-memory processing based on a unit that can both store and process data using the same cells. This unit, called a memristive memory processing unit (mMPU), will substantially reduce the necessity to move data in computing systems, solving the two main bottlenecks exist in current computing systems, i.e., speed ('memory wall') and energy efficiency ('power wall'). Emerging memory technologies, namely memristive devices, are the enablers of the mMPU. While memristors are naturally used as memory, these novel devices can also perform logical operations using a technique we have invented called Memristor Aided Logic (MAGIC). This combination is the basis of mMPU.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["757259"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY", "TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY"], "EU_Contribution": ["EUR 1 486 480"], "Project_Title": ["The cost of limited communication bandwidth in distributed computing"], "Total_Cost": ["EUR 1 486 480"], "Country": ["Israel", "Israel"], "Project_ACR": ["BANDWIDTH"], "Technology_Description": "Distributed systems underlie many modern technologies, a prime example being the Internet. The ever-increasing abundance of distributed systems necessitates their design and usage to be backed by strong theoretical foundations.", "To": ["2023-05-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-06-01"], "Project_ID": ["755839"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["ECOLE NORMALE SUPERIEURE", "ECOLE NORMALE SUPERIEURE"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Exploring topological matter with atomic Dysprosium"], "Total_Cost": ["EUR 1 500 000"], "Country": ["France", "France"], "Project_ACR": ["TOPODY"], "Technology_Description": "Recently, topology stepped in an increasing number of areas in physics, including via the concept of topological phases of matter. In strongly interacting systems, topological phases may exhibit intricate quantum entanglement between their constituents, leading to fascinating physical properties, such as the emergence of anyons. Since the discovery of fractional quantum Hall states in 1982, the scientific community is awaiting further experimental advances: new types of strongly correlated states, observation/manipulation of anyons. In this field, ultracold atoms promise novel approaches with a specific degree of control. Yet, despite the recent creation of weakly interacting topological states with atomic gases, reaching the strongly correlated regime, with long-range quantum entanglement, remains an open challenge.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["756722"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["TEL AVIV UNIVERSITY", "TEL AVIV UNIVERSITY"], "EU_Contribution": ["EUR 1 492 249,99"], "Project_Title": ["Human Trafficking: A Labor Perspective"], "Total_Cost": ["EUR 1 492 249,99"], "Country": ["Israel", "Israel"], "Project_ACR": ["HumanTrafficking"], "Technology_Description": "This project conducts a theoretical, methodological, and normative paradigm shift in the research and analysis of human trafficking, one of the most pressing moral and political challenges of our times. It moves away from the currently predominant approach to trafficking, which focuses on criminal law, border control, and human rights, towards a labor-based approach that targets the structure of labor markets that are prone to severely exploitative labor practices. This shift represents an essential development both in the research of migratory labor practices and in the process of designing more effective, and more just, anti-trafficking measures, that are context-sensitive as well as cognizant to global legal and economic trends. The project will include four main parts: 1) Theoretical: articulating and justifying the proposed shift on trafficking from individual rights and culpabilities to structural labor market realities. 2) Case-studies: conducting a multidisciplinary study of a series of innovative case studies, in which the labor context emerges as a significant factor in the trafficking nexus \u2013 bilateral agreements on migration, national regulations of labor standards and recruiters, unionization, and voluntary corporate codes of conduct. The case studies analysis employs the labor paradigm in elucidating the structural conditions that underlie trafficking, reveal a thus-far mostly unrecognized and under-theorized set of anti-trafficking tools. 3) Clinical Laboratory: collaborating with TAUs Workers' Rights clinic to create a legal laboratory in which the potential and limits of the tools examined in the case studies will be tested. 4) Normative: assessing the success of existing strategies and expanding on them to devise innovative tools for a just, practicable, and effective anti-trafficking policy, that can reach significantly more individuals vulnerable to trafficking, by providing them with legal mechanisms for avoiding and resisting exploitation.", "To": ["2023-03-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-04-01"], "Project_ID": ["756672"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["THE UNIVERSITY OF WARWICK", "THE UNIVERSITY OF WARWICK"], "EU_Contribution": ["EUR 1 483 943"], "Project_Title": ["Singularities and Compactness in Nonlinear PDEs"], "Total_Cost": ["EUR 1 483 943"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["SINGULARITY"], "Technology_Description": "The emergence of singularities, such as oscillations and concentrations, is at the heart of some of the most intriguing problems in the theory of nonlinear PDEs. Rich sources of these phenomena can be found for instance in the equations of mathematical material science and hyperbolic conservation laws.", "To": ["2023-03-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-04-01"], "Project_ID": ["757254"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITY OF CYPRUS", "UNIVERSITY OF CYPRUS", "THE REGENTS OF THE UNIVERSITY OF CALIFORNIA"], "EU_Contribution": ["EUR 1 499 444"], "Project_Title": ["Decomposing Heterogeneity in Autism Spectrum Disorders"], "Total_Cost": ["EUR 1 499 444"], "Country": ["Cyprus", "Cyprus", "United States"], "Project_ACR": ["AUTISMS"], "Technology_Description": "Autism spectrum disorders (ASD) affect 1-2% of the population and are a major public health issue. Heterogeneity between affected ASD individuals is substantial both at clinical and etiological levels, thus warranting the idea that we should begin characterizing the ASD population as multiple kinds of \u2018autisms\u2019. Without an advanced understanding of how heterogeneity manifests in ASD, it is likely that we will not make pronounced progress towards translational research goals that can have real impact on patient\u2019s lives. This research program is focused on decomposing heterogeneity in ASD at multiple levels of analysis. Using multiple \u2018big data\u2019 resources that are both \u2018broad\u2019 (large sample size) and \u2018deep\u2019 (multiple levels of analysis measured within each individual), I will examine how known variables such as sex, early language development, early social preferences, and early intervention treatment response may be important stratification variables that differentiate ASD subgroups at phenotypic, neural systems/circuits, and genomic levels of analysis. In addition to examining known stratification variables, this research program will engage in data-driven discovery via application of advanced unsupervised computational techniques that can highlight novel multivariate distinctions in the data that signal important ASD subgroups. These data-driven approaches may hold promise for discovering novel ASD subgroups at biological and phenotypic levels of analysis that may be valuable for prioritization in future work developing personalized assessment, monitoring, and treatment strategies for subsets of the ASD population. By enhancing the precision of our understanding about multiple subtypes of ASD this work will help accelerate progress towards the ideals of personalized medicine and help to reduce the burden of ASD on individuals, families, and society.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Cyprus"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["755816"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM", "THE UNIVERSITY OF BIRMINGHAM"], "EU_Contribution": ["EUR 149 688"], "Project_Title": ["Direct detection of cancer-causing mutations in tumour specimens"], "Total_Cost": ["EUR 149 688"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["INSITUMUT"], "Technology_Description": "Cancers develop because they acquire changes (mutations) in a specific set of genes that promote their growth. Different mutations are associated with cancer aggressiveness, patient prognosis and/or the response to treatment. Although these mutations can usually be detected by extracting DNA from tumour specimens, this provides incomplete information because it is common for mutations not to occur in every cell that makes up the cancer. In a number of research and clinical settings, it is of great use to learn which regions or cells within a cancer carry a particular mutation. To do this, we need to detect mutations in space by examining sections of tissue. There are several potential benefits, including sensitive detection of cancer cells that have been left behind after operation or that will cause relapse after treatment. Here, we shall develop a method to detect mutations in situ in cancer specimens. The INSITUMUT technique uses molecular probes that are specific to mutations in cancer genes and bind to RNA expressed from those genes. We have piloted the method successfully in collaboration with Advanced Cellular Diagnostics Inc., sensitively identifying cancer cells that have acquired specific mutations in the oncogene KRAS and specifically distinguishing them from cells and cancers with normal KRAS. Before making the method available, our workplan in this proposal involves determining probe sensitivity and specificity more accurately, expanding the range of cancer-causing mutations that are detected, developing methods for simultaneous detection of multiple mutations, extending the technique as far as possible to detection of mutations in DNA, and automating the mutation detection process. Subject to technical feasibility and commercial assessments, we shall disseminate the INSITUMUT method to non-profit sectors on a cost recovery basis, and make it generally available as a commercial service in partnership with SME partner Oxford Cancer Biomarkers.", "To": ["2019-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["755211"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["THE HEBREW UNIVERSITY OF JERUSALEM", "THE HEBREW UNIVERSITY OF JERUSALEM"], "EU_Contribution": ["EUR 1 570 000"], "Project_Title": ["Translating rewards to eye movements"], "Total_Cost": ["EUR 1 570 000"], "Country": ["Israel", "Israel"], "Project_ACR": ["iMove"], "Technology_Description": "The drive for rewards controls almost every aspect of our behavior, from stereotypic reflexive behaviors to complex voluntary action. It is therefore not surprising that the symptoms of neurological disorders that interrupt reward processing, such as those stemming from drug-abuse and depression, include deficits in the capacity to make even simple movements. Accordingly, how do rewards drive and shape movements? The brain uses two major subcortical networks to drive behavior: the basal ganglia and the cerebellum. Both areas are essential for the control of movement as damage to either structure leads to severe motor disabilities. Research on the basal ganglia has highlighted their importance in the control of reward-driven behavior-but how the reward information interacts with sensorimotor signals to drive the motor periphery is unknown. By contrast, research on the cerebellum has focused primarily on how sensory error signals are used to optimize motor commands but has mostly ignored the modulatory factors that influence behavior, such as reward. My goal is to unify research on the basal ganglia and cerebellum in order to understand how the computations underlying the influence of reward on action are implemented in the brain. I hypothesize that rewards drive and shape the motor commands in both subcortical networks, albeit with differing behavioral functions. While in the basal ganglia, information about reward is used to mediate selection between multiple actions; I predict that, in the cerebellum, reward potentiates movements to drive more accurate behavior. I will use the monkey smooth pursuit eye movement system as a powerful model motor system to study the neural mechanisms by which reward influences motor processing. I will combine the use of novel behavioral paradigms together with novel application of neural recording and optogenetic stimulation in primates to probe activity of neurons in the cerebral cortex, basal ganglia, and cerebellum.", "To": ["2023-06-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-07-01"], "Project_ID": ["755745"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA", "NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA", "\"NATIONAL CENTER FOR SCIENTIFIC RESEARCH \"\"DEMOKRITOS\"\"\""], "EU_Contribution": ["EUR 149 730"], "Project_Title": ["Commercialization of a novel method for fabricating cheap tailor\u2013made superhydrophobic surfaces"], "Total_Cost": ["EUR 149 730"], "Country": ["Greece", "Greece", "Greece"], "Project_ACR": ["HYDROPHO-CHEAP"], "Technology_Description": "The aim of the HYDROPHO-CHEAP project is to optimize, protect, and commercialize a recently developed methodology that allowed us to achieve \u201ctailor-made\u201d control of the wettability of polymer surfaces, rendering them super water-repellent. ", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Greece"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2018-02-01"], "Project_ID": ["755412"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["BANGOR UNIVERSITY", "BANGOR UNIVERSITY", "QUEEN MARY UNIVERSITY OF LONDON"], "EU_Contribution": ["EUR 1 458 770"], "Project_Title": ["National parks and people: Resolving the links between poverty and rule-breaking"], "Total_Cost": ["EUR 1 458 770"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom"], "Project_ACR": ["WILDPOV"], "Technology_Description": "Poverty is frequently perceived to be the root cause of illegal natural resource use \u2013 the hunting or extraction of wildlife not sanctioned by the state. When unsustainable, such activities threaten conservation of ecosystems and endangered species. However, understanding what motivates individuals involved is a major challenge; understandably few are willing to discuss their motives for fear of punishment [1]. Furthermore, severe, multifaceted poverty overlaps with regions prioritised for their globally important biodiversity [2]. This association exacerbates the problem that illegal activities pose for policy-makers responsible for managing and policing the use of nature. The dominant approach to conserving biodiversity is to establish protected areas [3] which typically restrict resource use and manage infractions through law enforcement [4]. However, the designation of such areas does not guarantee compliance, as demonstrated by ongoing infractions [5] and its conspicuous profile on global policy agendas. This includes the 2030 Agenda for Sustainable Development which calls for urgent action to halt biodiversity loss and hunting of protected species [6]. Solving this problematic cocktail of poverty, exclusion from resources and drivers of illegal resource use requires a new approach to understanding why people break rules and to what extent poverty underpins behaviour. Recent advances in cutting-edge techniques for asking sensitive questions are paving the way towards a more accurate understanding of the prevalence and drivers of illegal acts [7]. Combining conservation social science with development studies, criminology and social psychology, this project will examine, for the 1st time, the relative importance of multidimensional poverty and socio-psychological characteristics in dictating people\u2019s involvement in illegal resource use which will be contextualised by histories of national park establishment and how the idea of illegality shifts through time.", "To": ["2023-05-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-06-01"], "Project_ID": ["755965"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITY OF YORK", "UNIVERSITY OF YORK"], "EU_Contribution": ["EUR 1 223 054"], "Project_Title": ["From mind to mind: Investigating the cultural transmission of intergroup bias in children"], "Total_Cost": ["EUR 1 223 054"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["MINDTOMIND"], "Technology_Description": "Prejudice and discrimination are pressing social problems. Across Europe, the far right is on the rise, and individuals are often discriminated against on the basis of their race, gender or sexual orientation. The origins of these problematic attitudes and behaviours appear early in development, suggesting that we are passing on our biases to our children. Yet, our knowledge of the complex psychological processes by which these biases are learned remains rudimentary. MINDTOMIND experimentally investigates how children encode, select and transmit biased social information, and so provides a framework for understanding how intergroup attitudes are perpetuated across generations. ", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["755719"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["PARMENIDES STIFTUNG", "PARMENIDES STIFTUNG", "ECOLE SUPERIEURE DE PHYSIQUE ET DECHIMIE INDUSTRIELLES DE LA VILLE DEPARIS"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["OncoSeq: an innovative single-cell system for immunomonitoring"], "Total_Cost": ["EUR 150 000"], "Country": ["Germany", "Germany", "France"], "Project_ACR": ["OncoSeq"], "Technology_Description": "Host immunity plays a central and complex role in tumour progression, and the quality and quantity of immune infiltrate at the tumour site is used as a prognostic marker of cancer progression. Therefore, detailed single-cell analysis of tumor infiltrating immune cells, and ultimately liquid biopsy of circulating immune cells, is of vital importance for the development of new and improved immunotherapy strategies, and for diagnosis, prognosis, patient stratification and follow-up.", "To": ["2018-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["780964"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "MASSACHUSETTS INSTITUTE OF TECHNOLOGY"], "EU_Contribution": ["EUR 269 857,80"], "Project_Title": ["Cavity-mediated entanglement of trapped-ion qubit arrays for quantum information processing"], "Total_Cost": ["EUR 269 857,80"], "Country": ["United Kingdom", "United States"], "Project_ACR": ["CMEQIP"], "Technology_Description": "Long-coherence times, high-fidelity individual-ion control and entanglement-mediating Coulomb interactions make trapped-ion qubits a very attractive platform for quantum information processing (QIP). Entangling gates performed by coupling the internal states of ions in the same potential well via their shared motional mode have recently reached the high fidelities necessary for the implementation of quantum error correction protocols which can enable fault-tolerant QIP. However, scaling this type of gate up to long ion chains (>20 ions) is not feasible: large ion numbers lead to crowding of the motional mode spectrum of the chain, eventually preventing addressing of specific modes.", "To": ["2021-10-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-11-01"], "Project_ID": ["753788"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ECOLE NORMALE SUPERIEURE", "ECOLE NORMALE SUPERIEURE"], "EU_Contribution": ["EUR 1 499 125"], "Project_Title": ["Geodetic data assimilation: Forecasting Deformation with InSAR"], "Total_Cost": ["EUR 1 499 125"], "Country": ["France", "France"], "Project_ACR": ["GEO-4D"], "Technology_Description": "Recent space-based geodetic measurements of ground deformation suggest a paradigm shift is required in our understanding of the behaviour of active tectonic faults. The classic view of faults classified in two groups \u2013 the locked faults prone to generate earthquakes and the creeping faults releasing stress through continuous aseismic slip \u2013 is now obscured by more and more studies shedding light on a wide variety of seismic and aseismic slip events of variable duration and size. What physical mechanism controls whether a tectonic fault will generate a dynamic, catastrophic rupture or gently release energy aseismically? Answering such a fundamental question requires a tool for systematic and global detection of all modes of slip along active faults.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["758210"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 123 138"], "Project_Title": ["Large Deviations and Rare Transitions in Turbulent flows"], "Total_Cost": ["EUR 123 138"], "Country": ["France"], "Project_ACR": ["TransTurb"], "Technology_Description": "Many out-of-equilibrium systems undergo transitions from one quasi-stationary state to a radically different one.", "To": ["2019-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2017-12-01"], "Project_ID": ["753021"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["TRANSMODE SYSTEMS AB"], "EU_Contribution": ["EUR 185 857,20"], "Project_Title": ["NExt-generation WDM Metro and Access Networks"], "Total_Cost": ["EUR 185 857,20"], "Country": ["Sweden"], "Project_ACR": ["NEWMAN"], "Technology_Description": "The primary goal of the NEWMAN project is to train a talented researcher with a strong academic background in fibre-optic communication, through a research programme focused on developing next generation wavelength-division-multiplexing (WDM) technologies, and their usage as a for metro and access optical communication networks. The aimed WDM technologies supporting low-cost low energy consumption are highly desirable, since the number of metro and access links are forecasted to be massive in the next generation networks and will contribute to major portion of total energy consumption of the global network. The success of this project will contribute knowledge to the fields of laser science and fibre-optic technology, and establish an internationally leading position for Europe in the industrial applications relevant to fibre-optic networks.", "To": ["2020-02-29, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-SE - Society and Enterprise panel"], "Coordinated_in": ["Sweden"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-03-01"], "Project_ID": ["752826"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 1 445 000"], "Project_Title": ["Cooperative Catalysis: Using Interdisciplinary Chemical Systems to Develop New Cooperative Catalysts"], "Total_Cost": ["EUR 1 445 000"], "Country": ["Spain", "Spain"], "Project_ACR": ["CoopCat"], "Technology_Description": "Catalysis, a multidisciplinary science at the heart of many industrial processes, is crucial to deliver future growth and minimize anthropogenic environmental impact, thus being critical to our quality of life. Thus, the development and fundamental understanding of innovative new catalyst systems has clear, direct and long-term benefits to the chemical manufacturing sector and to the broader knowledge-based economy.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-02-01"], "Project_ID": ["756575"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["NATIONAL UNIVERSITY OF IRELAND GALWAY"], "EU_Contribution": ["EUR 175 866"], "Project_Title": ["SUGARSmart: Smart design of recombinant antibody fragments specific for carbohydrate molecules"], "Total_Cost": ["EUR 175 866"], "Country": ["Ireland"], "Project_ACR": ["SUGARSmart"], "Technology_Description": "The development of new approaches to explore the diverse role of glycans in normal and physio- pathological conditions of the cell is a major challenge. Our previous research recognized roles of anti-glycan recognition molecules (lectins and antibodies) in the diagnosis of diseases like cancer, immunity, and hyperacute rejection upon bioprosthetic transplantation etc. However, because of the structural complexity, well-established approaches for developing glycan-based therapeutics are limited.", "To": ["2020-05-14, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-05-15"], "Project_ID": ["747948"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CENTRE DE RECERCA EN AGRIGENOMICA CSIC-IRTA-UAB-UB"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Exploring the role of the mitochondrial alternative respiration in carotenoid biosynthesis during tomato fruit ripening"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["ARCATOM"], "Technology_Description": "Tomato is one of the most economically relevant crops in the world and is the main model system for fruit ripening studies at biochemical, genetic and molecular levels. In this climacteric fruit, a sudden increase in respiration takes place at the onset of ripening, usually in concert with increased production of ethylene that eventually impacts fruit color, firmness, taste, and flavor. During ripening, tomato accumulates high contents of health-promoting carotenoids (pro-vitamin A, antioxidants), which require a high production of carbon precursors and ATP. In this respect, both mitochondrial and chromoplast respiration have been proposed to play important roles in fruit ripening and carotenoid metabolism. The general aim of this project is to determine the contribution of mitochondrial respiration to the supply of energy and carbon for the production of carotenoids in tomato fruit during ripening. In particular, we will perform metabolomics of genetically modified tomatoes with altered mitochondrial and chromoplast respiration at different ripening stages. Furthermore, 13C- and 14C-labelling experiments will be performed to trace the fate of carbon from primary to secondary metabolites. In parallel, we will measure the relative glycolytic and TCA cycle fluxes and, for the first time in tomato, the in vivo activities of mitochondrial electron transport chain pathways by using the 18O fractionation technique. Combining these data with the analysis of transcript and protein levels of the main components of respiratory and carotenoid pathways and mathematical modelling will unveil novel metabolic checkpoints and connections between primary and secondary metabolism during fruit ripening. The generated new insights should contribute to the implementation of new biotechnological approaches to produce fruits with enhanced levels of carotenoids and other health-promoting secondary metabolites.", "To": ["2020-09-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2018-10-01"], "Project_ID": ["753301"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ATHENS UNIVERSITY OF ECONOMICS AND BUSINESS - RESEARCH CENTER"], "EU_Contribution": ["EUR 152 653,20"], "Project_Title": ["Video streaming services with Software-Defined Networking"], "Total_Cost": ["EUR 152 653,20"], "Country": ["Greece"], "Project_ACR": ["VSDN"], "Technology_Description": "Recent advances in mobile devices and video streaming services have motivated large-scale media consumption both in fixed and mobile environments. In this context, the main objective of network operators and service providers is to improve the Quality of Experience (QoE) of the end-users by providing high quality services and mechanisms for seamless", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["Greece"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["753685"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["SCIENCE AND TECHNOLOGY FACILITIES COUNCIL"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Direct and indirect searches for new physics in events with top quarks using LHC proton-proton collisions at the CMS detector"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["LHCTOPVLQ"], "Technology_Description": "We look for new physics in events with top quarks using LHC proton-proton collisions at the CMS detector. A direct search for top quark partners in the form of vector-like quarks is performed, complemented by an indirect but model-independent search for new physics interacting with top quarks using precision top quark properties measurements. In order to enable these and similar analyses to continue at the future High Luminosity LHC, we study the performance of the upgraded track trigger for events with top quarks, including optimisation of reconstruction algorithms and working points.", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations"], "From": ["2017-11-01"], "Project_ID": ["752730"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KERRY INGREDIENTS (IRELAND) LIMITED"], "EU_Contribution": ["EUR 187 866"], "Project_Title": ["Vegetable proteins: a novel source of next generation functional hydrolysates"], "Total_Cost": ["EUR 187 866"], "Country": ["Ireland"], "Project_ACR": ["VegProtein"], "Technology_Description": "Research is now focused on the potential contribution of plant-based proteins to help solve key issues pertaining to global food security. Protein hydrolysates have numerous properties which make them an attractive protein source in human nutrition and are utilized in many commercial food applications. Hydrolysed vegetable proteins (HVP) have demonstrated bioactive and techno-functional properties that can be further exploited for the development of functional-foods. The HVP market is dominated by soy varieties, and there is now a growing demand for alternative plant based sources. However, significant research advances are required in order to increase the direct use of plant protein for human food consumption, with a particular emphasis on extraction and processing technologies used to derive increased nutritional value and improved functional physical properties. From a commercial standpoint, vegetable proteins have taste attributes such as chalkiness and bitterness which present a major challenge in commercialization. This project will address the significant potential for application of superior tasting vegetable protein hydrolysates with improved food use properties for the functional foods market globally; this will be achieved by investigating the efficacy of a range of commercially available proteases in producing HVPs under controlled enzymatic conditions using a variety of vegetable substrates. Degree of hydrolysis, protein recovery, chemical composition and techno-functional properties of HVPs will be compared/contrasted before further optimization of characters, e.g. de-bittering, solubility, necessary for the their implementation in end use markets. Our primary goal is to engineer a clean tasting HVP with improved sensory and techno-functional capacity and an enzyme system suitable for its production.", "To": ["2019-11-05, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-SE - Society and Enterprise panel"], "Coordinated_in": ["Ireland"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-11-06"], "Project_ID": ["752923"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["SYDDANSK UNIVERSITET", "INSTITUTO SUPERIOR DE ENGENHARIA DE LISBOA", "PANEPISTIMIO PATRON", "CONSIGLIO NAZIONALE DELLE RICERCHE", "CHIMIKOTECHNOLOGITCHEN I METALURGITCHEN UNIVERSITET", "UNIVERSIDAD DE SALAMANCA", "UNIVERSITY COLLEGE LONDON", "INSTITUT PO INZHENERNA HIMIYA", "SANTZOUK SAMIR & CO GENERAL PARTNERSHIP", "UNIVERSIDADE FEDERAL DO PARANA", "TEXAS ENGINEERING EXPERIMENT STATION - TEES", "TECNOLOGICO NACIONAL DE MEXICO"], "EU_Contribution": ["EUR 594 000"], "Project_Title": ["Integrated Process and Product Design for Sustainable Biorefineries"], "Total_Cost": ["EUR 684 000"], "Country": ["Denmark", "Portugal", "Greece", "Italy", "Bulgaria", "Spain", "United Kingdom", "Bulgaria", "Greece", "Brazil", "United States", "Mexico"], "Project_ACR": ["IProPBio"], "Technology_Description": "Bio-based economy in Europe involves 22 million people and turns over roughly 2.4 billion \u20ac. The full realization of its huge potential, however, requires expert knowledge and synergy of different competencies. In particular, key questions and bottlenecks awaiting clear answers are:", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["778168"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["INSTYTUT CHEMII FIZYCZNEJ POLSKIEJ AKADEMII NAUK"], "EU_Contribution": ["EUR 134 462,40"], "Project_Title": ["Ultrafast photonics for the detection and recognition of toxic spine-structures of amyloid aggregates linked to neurodegenerative disease"], "Total_Cost": ["EUR 134 462,40"], "Country": ["Poland"], "Project_ACR": ["UPRECON"], "Technology_Description": "Projections indicate that, by 2050, every person aged 85 years or more will be diagnosed with a cognition-related disease. While there is currently no clear strategy for curing such diseases, there are promising developments in the early diagnosis of disease and the inhibition of worsening symptoms. Building on results obtained during my post-doctoral work regarding laser technology for amyloid aggregates detection, I propose to use an advanced ultrafast spectroscopy for structural analyses of the peptides and proteins that form the different fibril architectures in the brains of patients with pathogenic aggregates. In combination with multiphoton absorption, this laser technique has the potential to detect and diagnose in a non-invasive modality the early forms of toxic oligomeric intermediates in the brains of persons with suspected Alzheimer\u00b4s or Parkinson\u00b4s disease. This methodology has potentially enormous benefits for patients and society. Importantly, the proposed approach of using high-intensity light in the infrared region of absorption does not damage cells and tissues during long-duration irradiation, it does not require the use of chemical labels, and it reduces the need for surgical intervention, as it is non-invasive and safe for human health. I will transfer the knowledge and expertise on biophotonics of amyloid fibrils to Europe and the Host laboratory at the Polish Academy of Science will provide me with advanced training in time-resolved ultrafast laser spectroscopy and access to newly designed setups, as well as supplementary career path-specific training in ancillary skills.", "To": ["2020-02-29, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Poland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["750917"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CENTRE EUROPEEN D'ETUDE DU DIABETE"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Cross-talk between skeletal muscle and pancreatic islets: impact of exosomes"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["ExoDia"], "Technology_Description": "The worldwide explosion of obesity has resulted in an ever-increasing prevalence of type 2 diabetes (T2D), a non-communicable disease that affects more than 370 million people worldwide. T2D is characterized by insulin resistance with a relative deficiency in insulin secretion. It is now recognized that there is decreased beta-cell function and mass in T2D but the precise underlying mechanism remains to be determined. Skeletal muscle accounts for >50% of the total glucose uptake in the post-prandial state, it is also the largest organ in non-obese individuals. Recent studies demonstrated that there is conversation between skeletal muscle and beta-cells, and that certain peptides (i.e. myokines) secreted by insulin-resistant skeletal muscle cells may impact negatively on beta-cell function, proliferation and survival in T2D. Nevertheless, other factors than myokines could also be involved in this inter-organ communication. A novel concept suggests microvesicles, such as exosomes, as a new cell-to-cell communication mode. The major goal of the project will be to characterize the different exosomes populations and their impact on islets cells. The findings may have important implications for understanding decreased functional beta-cell mass in diabetes, especially in T2D etiology, and therefore bring new insights into the development of innovative therapies. ", "To": ["2020-01-01, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-SE - Society and Enterprise panel"], "Coordinated_in": ["France"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-01-02"], "Project_ID": ["753670"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FUNDACAO CALOUSTE GULBENKIAN"], "EU_Contribution": ["EUR 160 635,60"], "Project_Title": ["Control of disease tolerance to infection by Biliverdin Reductase A"], "Total_Cost": ["EUR 160 635,60"], "Country": ["Portugal"], "Project_ACR": ["BILITOLERANCE"], "Technology_Description": "The immune system was shaped through evolution, primarily through the selective pressure imposed by pathogens. This led to the emergence of multiple mechanisms that limit the negative impact of pathogens on host health and fitness. The best recognized defense strategy against infections relies on resistance mechanisms that aim at pathogen containment, expulsion or clearance. While crucial for host survival to infection, resistance mechanisms can carry significant trade-offs, often driven by oxidative stress and damage imposed to host parenchyma cells, and in some cases compromising the functional output of host tissues, i.e. immunopathology. Presumably for this reason, resistance mechanisms are coupled to countervailing oxidative stress responses that preserve parenchyma tissue function. These provide tissue damage control without exerting a direct negative impact on pathogens and as such are said to confer disease tolerance to infection. This defense strategy relies on the expression of a number of evolutionary conserved effector genes controlling the pro-oxidant effects of iron and heme, as illustrated for the heme catabolizing enzyme heme oxygenase 1 or the iron sequestering protein ferritin H chain. BILITOLERANCE aims at identifying and characterizing an unexplored and possibly central component of this tissue damage control mechanism that relies on the conversion of the end-product of heme catabolism biliverdin into bilirubin, by biliverdin reductase A (BVRA). The central hypothesis to be tested by BILITOLERANCE is that bilirubin generated by BVRA provides a potent lipophilic anti-oxidant defense mechanism that limits the deleterious effects of lipid peroxidation. Moreover BILITOLERANCE will test the hypothesis that bilirubin also signals via the aryl hydrocarbon receptor (AhR) to modulate the activation of tissue-resident macrophages and promote tissue damage control and disease tolerance to infection.", "To": ["2020-11-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Portugal"], "Activity": ["Research Organisations"], "From": ["2018-12-01"], "Project_ID": ["753236"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN"], "EU_Contribution": ["EUR 187 866"], "Project_Title": ["Computer-aided Van der Waal Heterostructure Device Design using Unique Response to Electric Fields"], "Total_Cost": ["EUR 187 866"], "Country": ["Ireland"], "Project_ACR": ["VHDD"], "Technology_Description": "The van der Waals heterostructure has been a central focus of materials research and nanotechnology for a decade. It is because this heterostructure can provide device platform highly flexible for materials combination. Thanks to those advantages, this heterostructure system is highlighted for potential application for flexible and low-power consumption electronics. In this research proposal, we will propose new device architecture using novel 2D physics under an electric field. Because of its low-dimensional nature and transparency of electric field, the band structure at the heterostructure can be remarkably modulated. Our objective is to design new device architecture using this phenomenon. To achieve it, we will find out best heterostructure using high-throughput calculations and will design the device architecture. Then, we will simulate the device characteristics using DFT-NEGF method and validate it experimentally. This approach is pioneering for coming up with new device architecture, which will open a new direction beyond the state-of-the-art. Thanks to its novelty, it is expected to have a high impact in the fields of physics, materials science, and nanoelectronics. Through this research project, the applicant will obtain valuable opportunity for career development and will promote interdisciplinary nature of this research field.", "To": ["2020-11-19, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-11-20"], "Project_ID": ["751581"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF SHEFFIELD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["optimal design of Admixtures for concrete embedded Large Scale Antenna Array"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["AceLSAA"], "Technology_Description": "Large scale antenna array (LSAA) has been introduced into 5G cellular networks to address the capacity crunch indoors. LSAAs will increase the physical dimension of the base station (BS), generating negative consequences on weight, wind load and visual impact. A potential solution of deploying LSAA indoors is to embed it into building structures, e.g., concrete walls. However, how the concrete impacts the wireless performance of concrete embedded antenna array (CEAA) has not been well studied. In this project, we will investigate how the electromagnetic (EM) properties of concrete will impact the wireless performance of CEAAs, and how to design and optimise the building properties of concrete to achieve both desirable mechanical and wireless performance. First, we will define metrics so that the wireless performance of CEAA can be measured. EM properties of concrete and the inhomogeneity of EM properties will be taken into account. Then, we will establish the relationship between the ratio and layout of admixtures and the EM properties of concrete. Three simplified concrete model, i.e., multilayer, lattice and 3D Poisson point process (PPP) models, will be proposed and verified through simulations and measurements. Finally, we will design concrete with desirable EM properties by changing the ratio and layout of admixtures under the constraint of mechanical performance to obtain an optimal wireless performance. After the completion of this project, we will be able tell how to optimize wireless performance of concrete under the constraint of its mechanical performance for typical building structures.", "To": ["2020-11-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-12-01"], "Project_ID": ["752644"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FONDATION NATIONALE DES SCIENCES POLITIQUES"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Male Family Caregiver\u2019s Well-being: Balancing Work and Long-Term Care in France and Japan"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["CAREANDWORK"], "Technology_Description": "Rapid demographic ageing in Europe, as highlighted in Horizon 2020 health priorities, makes the challenge of long-term care increasingly pressing. Despite substantial discussions on caregivers in policy making and academic research, a rapidly emerging new group of relatively young male family primary caregivers who often also work are largely understudied and increasingly risk giving up their employment. Inadequate understanding of gendered caregivers jeopardises not only carers but also care receivers, other family members and society as a whole: better outcomes for the elderly are substantially dependent on the well-being of caregivers. For Europe it is relevant and timely to learn from \u2018super-aged\u2019 Japan about such gendered carers\u2019 practices, particularly their use of innovative \u2018technologised care\u2019 emphasised by Japan\u2019s large-scale welfare programme. Yet, learnings need to be contextualised to reflect European societies, such as France\u2019s highly developed family policies. Hence, this project aims to address the gap in understanding of gendered male family care practices to inform policy development, focusing on the relevance and application in France of practices from Japan. This project will develop an innovative multidisciplinary approach to comparative understanding and policy development: building on the researcher\u2019s anthropological PhD on men and masculinities in family the project develops \u2018short-duration fieldwork\u2019 in Paris and Tokyo, which is complemented by capabilities developed through training by hosts Science Po and Oxford in sociology and policy analysis. The project findings will be disseminated to potential users, such as policy makers, academic and non-academic researchers, also by organising an international workshop and to the public through popular media. The research project develops the researcher\u2019s specific capabilities and transferable professional skills that substantially open up new career paths, notably in policy research in Europe.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["753717"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITEIT LEIDEN"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["Cyclometallated ruthenium complexes for photo-activated chemotherapy"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["CylcoRu4PACT"], "Technology_Description": "Chemotherapy is efficient in curing cancer, but most treatments are very hard to stand for the patient, and side effects limit treatment efficacy. Phototherapy is a promising alternative, where the toxicity of a light-sensitive chemotherapeutic compound is locally released upon visible light irradiation of the compound-containing tumour. Photodynamic therapy is already available in the clinic for oxygen-rich tumours; however, it fails when the oxygen concentration at the place of irradiation is too low. In this project I propose to synthesize new ruthenium-based photochemotherapeutic compounds containing cyclometallated ligand, and to test them in an in vitro model of hypoxic cancer. The presence of a carbon-metal bond is known to shift the light absorption properties of ruthenium polypyridyl complexes towards the photodynamic window, a wavelength range where light penetrates optimally into biological tissues. However, cyclometallation usually quenches the ligand photosubstitution properties of ruthenium compounds because it strongly modifies the energy of their excited states. In this project, I will introduce sterically hindering groups on the cyclometallated ligand to recover photoreactivity of the complexes while keeping light absorption at high wavelengths. The challenges of this project consist on the one hand in achieving efficient ligand photosubstitution reactions with cyclometallated ruthenium compounds, and on the other hand in minimizing the cytotoxicity in the dark while maximizing cytotoxicity after red light irradiation at low oxygen concentrations. The ruthenium prodrugs will be synthesized, their photochemical properties will be measured, and their cytotoxicity against human cancer cell lines will be determined in an in vitro model of hypoxic cancer. This project will set new grounds in the treatment of hypoxic tumours and propose a new way to overcome side effects occurring in traditional anticancer chemotherapy.", "To": ["2020-05-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-06-01"], "Project_ID": ["750686"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Being precautionary: how rational? How ethical?"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["Precaution"], "Technology_Description": "Human decisions can be evaluated on whether they exemplify some precaution. For instance, the mayor was praised for being precautionary in reinforcing the dike along the river. Precaution has recently been raised at the level of a principle \u2013 the Precautionary Principle \u2013 which has acquired a widely recognized status in national and international law. This project conducts a philosophical analysis of conceptual and fundamental issues on the Precautionary Principle and on precaution more generally. I aim at understanding why being precautionary makes sense from a rational viewpoint, both at the individual (Objective A) and collective (Objective B) levels, and from an ethical viewpoint (objective C).", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["749425"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE DE BRETAGNE OCCIDENTALE", "UNIVERSITY OF WASHINGTON"], "EU_Contribution": ["EUR 246 668,40"], "Project_Title": ["MEchanisms of Coupling of Ocean Dynamics and Intermediate trophic levels: High Resolution study"], "Total_Cost": ["EUR 246 668,40"], "Country": ["France", "United States"], "Project_ACR": ["MECODIHR"], "Technology_Description": "\"The open ocean is the largest biome on Earth, yet it is the least protected. A major obstacle to its conservation lies in the fine-grained understanding of how marine organisms are affected by the ocean dynamics. In the last decades remote sensing and bio-logging drastically increased our understanding to how phytoplankton (that can be observed from space as ocean color) and large marine animals (that can be followed with sensors directly attached to them) responds to oceanic turbulence down to the mesoscale (few weeks-months, 10-100 km). A major knowledge gap still concerns the so-called \"\"intermediate trophic levels\"\" (ITLs, i.e. zooplankton and micronekton,) and how mesoscale currents (such as fronts and eddies) affect them. This is the focus of the MECODIHR project. ", "To": ["2021-09-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-10-01"], "Project_ID": ["749591"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["POLITECHNIKA WROCLAWSKA"], "EU_Contribution": ["EUR 146 462,40"], "Project_Title": ["Photo/magnetic stimulated nanocargos for superior cancer treatments"], "Total_Cost": ["EUR 146 462,40"], "Country": ["Poland"], "Project_ACR": ["NANOCARGO"], "Technology_Description": "Breast cancer (BC) accounts for 28 % of the total cancer cases in the European Union (EU) and is the leading cause of cancer-related mortality of European women. The stratification of individual BC sub-types for corresponding therapy modalities is poor. Therapy outcomes in several BC sub-types are unsatisfactory. Its diagnosis is marred by high proportion of false positives and the economic burden to healthcare systems is very high. To overcome this NANOCARGO will develop a simultaneous diagnosis and therapy (theranostics) approach based on a multimodal nanocomposite termed as nanocargos. The battle against cancer is much more effectively fought if it is aided by early detection and, potentially concurrent, efficient treatment. NANOCARGO, introduces a new paradigm that theranostics can be made far more effective if a multimodal action can be integrated by adding a plasmonic shell to a magnetic nanoparticle core. The plasmonic shell can be functionalized with the chemotherapeutic drugs and aptamars. Magnetic@gold and magnetic@silver type core/shell nanocargos can be conjugated with anticancer aptamer. These nanocargos can be stimulated by simultaneous application of magnetic hyperthermia and photonic therapy. Cellular delivery can benefit from photoporation. Anticancer therapy can thus be made much more effective through the multimodal actions of these nanocargos exposed to endo-luminal, minimally invasive optical stimulation and extra-corporeal magnetic resonance imaging based excitation. Such a combined will maximise the delivery of these nanocargos into tumor cells. The magnetic core is advantageous for a controlled delivery of aptamer through an externally applied magnetic field. Gold and silver shell will support aptamer attachment. X-ray computed Tomography (CT) imaging contrast of absorbing tumors will be better due to higher X-ray absorption of gold and silver.", "To": ["2020-09-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Poland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-10-01"], "Project_ID": ["751903"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["DUBLIN CITY UNIVERSITY"], "EU_Contribution": ["EUR 175 866"], "Project_Title": ["Development of a Cavity Supported Lipid Membranes Biomimetic drug permeability models (CLIMB)"], "Total_Cost": ["EUR 175 866"], "Country": ["Ireland"], "Project_ACR": ["CLIMB"], "Technology_Description": "Permeability Assay (PAMPA) have limited biorelavance and can often be poorly predictive of of drug permeation, particularly for charged species and for complex membranes such as the BBB and particularly of membrane toxicity which remain key issue leading to high attrition rate and low productivity in the pharmaceutical industry. The proposed fellowship programme aims to address these issues in a very novel way by developing lipid bilayers supported on cutting-edge Plasmonically-Directed Nano-Structured porous arrays. The substrates prepared via a range of fabrication methods, including 2-photon 3D-nanoprinting, will allow for investigation of drug-membrane interactions, and permeability through a unique and novel principle, whereby the arrival time of single or few weakly- or non-fluorescent molecules at plasmonic volume in the nano-/micro-cavity is monitored via enhanced spectroscopic technique. Angle dependent Raman microscopy will permit study independently of the drug-membrane interactions and plasmonic hot spot so both structural and permeation times can be meausered and these studies will be carried out in parallel with Elelctrochemcial impendence spectroscopy of membrane integrity. This approach will dramatically advance the state-of-the-art in membrane assay. In parallel it provide high quality research training to the MRSA fellow along with, supported by the host institution training programme a range of career promoting transferable skills acquired. Leading the fellow to a fully-independent academic position.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["750601"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAT DE LES ILLES BALEARS"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Gravitational waves from extreme mass-ratio inspirals"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["GWsFromEMRIs"], "Technology_Description": "In 2016, the Laser Interferometer Gravitational-Wave Observatory (LIGO) collaboration announced its first ground-breaking detections of gravitational waves sourced by binary black hole mergers. These observations herald the beginning of a new era in astronomy: gravitational waves are expected to shed light on many unsolved astrophysical and theoretical problems, such as finding neutron stars' equation of state, modelling the formation and evolution of compact objects and testing alternative theories of gravity. ", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["751492"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["GOETEBORGS UNIVERSITET"], "EU_Contribution": ["EUR 185 857,20"], "Project_Title": ["Novel mechanisms of site-specific regulation of bone strength for the prevention of osteoporotic fractures: a translational project"], "Total_Cost": ["EUR 185 857,20"], "Country": ["Sweden"], "Project_ACR": ["GOTBONE"], "Technology_Description": "Osteoporosis is a major health concern characterized by reduced bone mineral density (BMD) and impaired microarchitecture leading to increased risk of fractures and mortality, especially at the hip. At least 40% of women and 15% of men will sustain one or more fragility fractures in their remaining lifetime, representing a huge economic burden in Europe. Currently available osteoporosis drugs are effective in reducing vertebral fracture risk (dependent on trabecular bone) while less effective for non-vertebral and hip fracture risk (dependent on cortical bone). This proposal aims to identify novel mechanisms regulating site-specific fracture risk, on the basis of recent human genetic findings on the determinants of cortical bone thickness (WNT16 locus) and trabecular volumetric BMD (GREM2 locus). This translational research program will study the role of the WNT lipase NOTUM in the regulation of cortical bone thickness via its interaction with WNT16, a key regulator of cortical bone identified by the proposed supervisor (Nature Medicine 2014). We will next study how the Bone Morphogenetic Protein antagonist GREM2 regulates trabecular BMD. These studies will be performed using genetically modified murine models and human cell-cultures systems. Finally, in a prospective population-based cohort study (n=3010), we will test if serum level of NOTUM predicts the risk of fractures. Our long term goal is to translate these findings into novel biomarkers and more effective therapies for the prevention of osteoporotic fractures.", "To": ["2019-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["750579"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 200 194,80"], "Project_Title": ["The geometry of chromatic categories"], "Total_Cost": ["EUR 200 194,80"], "Country": ["Denmark"], "Project_ACR": ["ChromoCats"], "Technology_Description": "This project studies the local and global structure of fundamental categories in topology, algebra, and algebraic geometry from a geometric point of view. Deep structural results have been proven in special cases, but the lack of a unified theory has prevented progress on several key conjectures, for example pertaining to local-to-global principles. ", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["751794"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Modelling cortical information flow during visuomotor adaptation as active inference in the human brain"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ViMoAct"], "Technology_Description": "Recent research suggests that to control bodily movements the brain relies on Bayes-optimal predictive models that are updated by sensory prediction error. This assumption may be generalised within a new formal account of motor control as active (Bayesian) inference. Active inference explains motor control in terms of hierarchical Bayesian filtering or predictive coding, i.e., as belief updating and suppression of prediction error to optimise a hierarchical generative model in the brain; thereby the weighting of prediction errors by their predicted precision determines their relative impact on hierarchical inference. This novel proposal still lacks concrete empirical investigation. The proposed project will close this research gap by testing whether cortical information flow during manual actions, requiring visuomotor adaptation and cognitive control of attention, follows the principles of active inference. In two fMRI experiments and one MEG experiment, participants will move a photorealistic virtual hand model via an MR-compatible data glove to perform simple manual tracking tasks in a virtual reality environment. The precision of prediction errors at multiple levels of a previously established cortical motor control hierarchy will be experimentally manipulated via visuoproprioceptive conflicts (introduced by delayed visual movement feedback) and via attentional allocation \u2013 either stimulus-driven (via increased sensory noise) or endogenous (instructed) \u2013 to visual or proprioceptive movement feedback. Active inference\u2019s specific predictions about information flow between and within cortical areas will be tested with recently established dynamic causal modelling of the modelled hemodynamic (fMRI) or spectral (MEG) responses. Active inference appeals to a general free-energy principle of brain function; this contribution will thus promote interdisciplinary exchange of knowledge about self- and world-representation in the brain and will be of general public interest.", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["749988"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN"], "EU_Contribution": ["EUR 187 866"], "Project_Title": ["The unseen adaptation of a non-native: A unique spatiotemporal study of infection dynamics and immunogenetics at a bioinvasion front"], "Total_Cost": ["EUR 187 866"], "Country": ["Ireland"], "Project_ACR": ["INVASIMMUN"], "Technology_Description": "Emerging infectious diseases (EIDs) are an increasing threat to global health and there is an urgent need to understand the processes involved in their spread. The majority of EIDs originate from wildlife, for example the recent outbreaks of ebola, zika virus and lassa fever. One of the primary drivers of EIDs is human intervention via host or parasite translocations. A unique opportunity to study the processes involved in EIDs, currently exists in Ireland due to the introduction of the bank vole (Myodes glareolus), via Germany in the 1920\u2019s. The continuing range expansion of the bank vole within Ireland presents a natural large-scale perturbation experiment, with empirical data and known expansion routes already available. This knowledge, which is based in part on data I am currently collecting, combined with bank voles being an established model species for studying disease dynamics, creates an ideal and rare system to study the factors that influence the invasion process and the emergence of infectious diseases. The primary objective of the proposal is to conduct a spatiotemporal study analysing the infection dynamics of native and invasive species in relation to immune phenotype. A temporal study will allow the process of adaptation, as the invasive species becomes established, to be observed for the first time. I will be mentored by and collaborate with world leaders in disease ecology in Ireland and other European countries to accomplish my goals. The Marie Sk\u0142odowska-Curie fellowship would enable me to build on my disease ecology research experience and to develop a unique bio-invasion model system in Europe. It will enable me to develop expertise in the emerging field of ecoimmunology, establishing my position as a key scientist in this innovative field of research.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["749312"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["West African Coastal Ocean - Finescale physics, biogeochemistry and climate change"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["WACO"], "Technology_Description": "Coastal oceans are essential to our societies but their health status is degrading rapidly in many parts of the world. Anticipating or remedying environmental evolutions/degradations, including those resulting from global changes, is particularly difficult. This is largely because the knowledge and information we currently have on the ocean functioning do not encompass scales finer than a few tens of kilometers, which is notably insufficient close to shores. WACO will clarify the role of fine-scale processes (turbulent and wave processes with scales < 10 km) in the present-day functioning and future evolutions of the West African coastal dynamics and biogeochemistry. To do so, it will take advantage of a new generation of ocean models that is truly apt to simulate coastal dynamics/biogeochemistry/ecosystems in a fully integrated and multi-scale manner. Precisely, the project will be focused on the senegalese and mauritanian coastal oceans from which state-of-the-art ocean observations are available to complement and evaluate the modelling effort, a robust and interdisciplinary collaborative framework, and unmatched opportunities for social benefits of the research. The project relies on a massively parallel computing plan that will serve as a demanding training ground for the applicant. Overall WACO will contribute to a deeper understanding of climate change, which is a key goal of EU research.", "To": ["2020-02-29, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["749699"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["STICHTING NIOZ, KONINKLIJK NEDERLANDS INSTITUUT VOOR ONDERZOEK DER ZEE"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["SICK OF NOISE - Effects of noise pollution on marine invertebrate health and species interactions"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["SICK OF NOISE"], "Technology_Description": "Noise is considered a threat to human health, causing not only annoyance or hearing impairment but also hypertension, ischemic heart disease and diabetes. Like humans, many animals can be affected by noise. Marine invertebrates, in particular, can be very sensitive to sounds and, because of their limited mobility, can be exposed to the disturbing noises of boat engines, windfarms and pile drivers over long periods of time. Such underwater noise pollution is known to have detrimental effects on the activity and physiology of marine invertebrates.", "To": ["2020-07-15, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Research Organisations"], "From": ["2018-07-16"], "Project_ID": ["750429"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE GRENOBLE ALPES"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Dual capillary waveguide endoscope"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["DARWIN"], "Technology_Description": "Photoacoustic imaging, an emerging multi-wave imaging modality that couples light excitation to acoustic detection via the photoacoustic effect (sound generation via light absorption), relies on detecting ultrasound waves that are very weakly scattered in biological tissue. It provides acoustic-resolution images of optical absorption non-invasively at large depth (up to several cm). However, ultrasound attenuation increases with frequency, limiting the depth-to-resolution ratio to about 100. An alternative to overcome the dispersion of light in tissue due to scattering is using thin, micron-sized diameter optical fibers to both deliver and collect light from the sample. A novel idea and preliminary proof-of-concept experiment has just been demonstrated by Prof. Bossy\u2019s team where a dual waveguide allows also to remotely detect high frequency ultrasound with the same device as that used for guiding light. This device can act both as a multi-mode optical waveguide for the illumination and fluorescence collection using the outer cladding, and as a waveguide to guide the ultrasound out of the tissue using the core, avoiding the absorption by the tissue and increasing the penetration depth.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["750420"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FUNDACIO CENTRE DE REGULACIO GENOMICA"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Exploring terra incognita: terrestrialization of arthropods in the era of genomics"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["TERRESTREVOL"], "Technology_Description": "Terrestrialization \u2013 the colonization of the land habitat by plants and animals \u2013 is amongst the most important events in the history of life on Earth. Understanding terrestrialization is, therefore, key to understanding biological adaptation. From all animals, arthropods constitute the most successful phylum, manifest in extreme species richness and successful radiation into nearly every ecological niche. Arthropods colonized the land multiple times independently and at different times in Earth history, with terrestrial arthropods massively outnumbering the aquatic ones. This begs the questions how, when, why and how often did arthropods become successful in the terrestrial environment, constituting ideal model systems to study terrestrial adaptations at the genomic, physiological and morphological levels. In order for animals living in aquatic environments to colonize land, a number of physiological barriers need to be overcome, including massive changes to methods of respiration, water management and osmoregulation, reproduction or digestion, among others. Water balance is one of the main challenges facing primarily terrestrial animals. Osmoregulation is also highly relevant to the question about the route taken onto land, specifically whether the ancestors of a given terrestrial arthropod group came directly from a marine environment or via fresh water. The main goal of this project is to shed light on the mode and tempo of these changes through the integration of phylogenomics, paleontology and comparative genomics and transcriptomics. For this, I propose to investigate i) the genetic basis of cuticular composition in marine and terrestrial arthropod lineages, ii) characterization of genes involved in osmoregulation, and iii) lineage-specific orphan gene families that could have contributed to arthropod evolvability in terrestrialization events. The results of this project will allow an unprecedented understanding of deep-time questions in arthropod evolution.", "To": ["2020-01-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2018-01-15"], "Project_ID": ["747607"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF GLASGOW"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["The World of the G\u00e1idhealtachd and the origins of the Early Modern British State, 1513-1594."], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["GEMS"], "Technology_Description": "By 1603 the political power of the Gaelic world, or G\u00e1idhealtachd, had been broken in the face of the recently created British state. Though certain Gaelic dynasties (i.e., the Campbells and O\u2019Briens) actively worked with the state, little research has been undertaken on how dynasties such as the O\u2019Donnells and O\u2019Neills possessed the capacity not only to resist but also to threaten this process of state formation throughout the 16th century. Using a series of case studies and drawing upon a broad base of primary material, this project explores the political and military development of the G\u00e1idhealtachd during two key phases of Anglo-Scottish relations. The first section investigates how certain Gaelic lords manipulated the course of Anglo-Scottish hostilities from 1513-59 in order to enhance their position within \u2018British\u2019 politics. The second section explores how the Gaelic lords reacted to the development of Anglo-Scottish peace and amity from 1560-94. The main objective of this project is therefore to uncover the basis for the strong level of Gaelic political and military resilience within \u2018British\u2019 politics throughout the 16th century and how significant a factor this was in contributing to the outbreak of the Nine Years War (1594-1603). This is an interdisciplinary project, involving Gaelic, English, Scottish, and Latin historical material as well as elements of literature and archaeology. The project will be strengthened by the experienced interdisciplinary research team at the University of Glasgow and will involve both the transfer of knowledge to the host institution and the training of the researcher in new competences. Ultimately, this project will make a major intervention in the history of Early Modern Ireland and Britain and will result in a series of high-impact publications. The proposal also entails a secondment to BBC Scotland and a detailed public engagement strategy aimed at changing public perceptions of 16th century Ireland and Britain.", "To": ["2020-09-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-10-01"], "Project_ID": ["750447"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF DURHAM"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Managing Risk in Early Complex Societies in Syria-Palestine: An Investigation of Changing Animal Herding Strategies through the 4th-2nd Millennia BC Using Multi-Element Isotopic Analysis"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["MRECS"], "Technology_Description": "The proposed research at Durham investigates the role of pastoral mobility in the rise of urban societies and large, integrated supra-regional economies in western Syria during the 3rd millennium BC through isotopic analysis of skeletal remains. During this period, state-level political systems developed and there was a massive expansion of urban settlement into the arid Syrian steppe. Scholars at Durham have proposed that elite exploitation of the economic opportunities provided by the humble sheep for the development of a vast new livestock-based economy lay at the heart of this transformation, representing a fundamental shift in socio-political networks, economic resilience and risk management strategies. Although material culture and texts provide clear indications about the vital significance of the wool industry in these major socio-economic changes, the proposed research will provide the first reliable means of directly testing these hypotheses by using multi-element isotopic analysis of archaeological animal enamel and bone to examine changes in animal management and herding strategies in Syria-Palestine in the 4th-2nd millennia BC. Two case studies will represent areas close to the core of this emerging system of economic intensification, and more peripheral areas that were likely impacted by these changes in more subtle ways.", "To": ["2020-07-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-08-01"], "Project_ID": ["749872"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO SANT'ANNA"], "EU_Contribution": ["EUR 180 277,20"], "Project_Title": ["NON-WESTERN MILITARY INTERVENTIONS AND THE CHARACTER OF WARFARE IN THE EUROPEAN PERIPHERY"], "Total_Cost": ["EUR 180 277,20"], "Country": ["Italy"], "Project_ACR": ["NWICWEP"], "Technology_Description": "While Western countries regularly intervene militarily abroad, recent years have seen increasing levels of military intervention by non-Western authoritarian and weakly-democratic states in the EU periphery. Non-Western interventions profoundly impact the security dynamics of an increasingly fragile EU neighbourhood. Despite this, the patterns and character of resulting conflicts are ill-understood, especially compared to recent conflicts involving Western states (on which much of the recent conflict literature is based). This project will conduct a highly original comparative analysis of three EU-periphery conflicts (Ukraine, Yemen and the West African Sahel) that have seen the involvement of four of the most militarily active non-Western states in the wider EU neighbourhood (Russia, Saudi Arabia, and Nigeria/Chad respectively). The fellowship will advance knowledge of: 1) how the character of conflict involving non-Western military powers differs from general conceptualizations of contemporary warfare (and each other); and, 2) how the character of these conflicts is comprehended strategically both by key state actors involved, and by Western security actors (EU and NATO). Such a project is timely given rising levels of conflict in the EU periphery and necessary given the absence of comparative enquiry into the evolving character of armed conflict across the wider EU neighbourhood. Through a mixed-methods analysis of three conflicts of critical importance to the EU, this project will offer innovative research findings on the causes, politico-military strategic logics, military practice and potential resolution of contemporary non-Western war that will support the EU\u2019s recently-developed 2016 \u2018Global Strategy\u2019 for the EU Foreign and Security Policy.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["748164"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Syntenin-phosphatidic acid interaction in exosome biogenesis and cell-cell communication: a structure-function based approach"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["EXOGENESIS"], "Technology_Description": "Cells communicate with their environment in various ways, including by secreting vesicles. Some of these extracellular vesicles originate from endosomes, are loaded with proteins, lipids and RNAs and are called exosomes. Exosomes emerge as important players in physiological cell-cell communication, but also in various systemic diseases. Understanding how cells control the selective incorporation of \u2018messages\u2019 in their exosomes is thus essential, and such fundamental new knowledge may allow us to better understand cancer spread for example. Recently syntenin, a small intracellular adaptor protein, was identified as essential for the biogenesis of presumably a distinct class of exosomes that might be important for cancer cell communication and systemic invasion. Based on preliminary work, this study aims to evaluate the role of the membrane lipid phosphatidic acid in the formation of syntenin exosomes, their loading with cargo and their function in intercellular communication. A structure-function based approach is used, allowing if successful to pave the way for rational and innovative drug intervention. The fellowship will offer the applicant the possibility to receive an intensive training in biochemistry, cellular, molecular biology and drug discovery as well as to acquire important secondary skills which will pave the way for his career as an independent researcher.", "To": ["2020-11-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2018-12-01"], "Project_ID": ["747025"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Looking at it from a different angle: The role of viewpoint-dependency in traumatic intrusions."], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["TRAUMA_CONTEXT"], "Technology_Description": "Many victims of psychological trauma suffer from recurrent intrusive trauma memories. According to Dual-Representation Theory (DRT), intrusive memories reflect functional deficiencies in the brain\u2019s hippocampal system, which fails to translate the egocentric perceptual impressions of the trauma into viewpoint-independent (or allocentric) spatial representations. This proposal tests this assumption and explores allocentric memory training as a potential novel intervention against intrusive memories.", "To": ["2020-03-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-04-01"], "Project_ID": ["749206"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE GLASGOW CALEDONIAN UNIVERSITY"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["GET READY - a unique intervention addressing activity reduction co-designed with Care Home residents and University students, following a service-learning methodology"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["GET READY"], "Technology_Description": "The \u2018Get Ready\u2019 project aims to integrate service-learning methodology into Physical Therapy and Sport Sciences University degrees by offering students individual service opportunities (placements) with Residential Care Homes, in order to co-create the best suited physical activity (PA)/ sedentary behaviour (SB) intervention with researchers, older adults (end-users) in care homes, health professionals and policy makers. The project will use a Participatory Action Research (PAR) methodology and will follow the objectives of workforce development to support users to demand more responsive and integrated care programmes for chronic diseases, and to involve end-users in their health management and decision-making relevant to their own health (Action Area 6). We will use mixed methods to assess the intervention feasibility and acceptability (including process evaluation) and we will conduct a pilot study of a two armed pragmatic randomized controlled trial to assess the effectiveness of a 12-week complex intervention on reducing SB and increasing PA, infused with behaviour change technologies, in an institutionalized older population. This complex intervention co-designed with care home residents and conducted by university students will be compared to existing PA interventions (usual care), conducted by health professionals working in the Residential Care Homes. The experienced researcher will significantly expand her scientific knowledge by combining it with the new themes of SB as a risk factor for health and its assessment in institutionalized older adults, shorten the gap between students and real life conditions, and the process of PAR methodology to co-create a robust intervention through workforce development with end-users, providing a logical progression and extension of her knowledge, enhancing the experienced researcher\u2019s academic skills and offering a distinct progression on wider academic (as opposed to purely research) skills.", "To": ["2020-01-21, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-22"], "Project_ID": ["747490"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF DUNDEE"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Unravelling the effect of origin number on the success of genome replication"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ORI NUMBER"], "Technology_Description": "DNA replication must be regulated in eukaryotic cells to ensure that the genome is precisely duplicated. The process is split into two non-overlapping stages: origin \u201clicensing\u201d and origin \u201cfiring\u201d. During licensing in G1, ORC loads MCM2-7 onto DNA, and during the firing stage in S phase MCM2-7 is activated to drive replication forks. To prevent re-replication of DNA no new origins must be licensed once S phase begins. Since replication forks can irreversibly stall, it is crucial that sufficient origins are licensed before S phase entry. The \u201clicensing checkpoint\u201d prevents cells in G1 with too few licensed origins from entering S phase. A number of different MCM and ORC mutations have been identified, leading to cancer susceptibility, proliferation defects and/or developmental abnormalities. However, it is hard to explain the spectrum of defects caused by specific mutations, such as in Meier-Gorlin Syndrome. In this project, I will use genome editing to engineer iPS cells with specific mutations in MCM and ORC proteins to determine the effects on origin licensing, licensing checkpoint activation and genome stability. I will use state-of-the-art quantitative proteomics, next generation sequencing and flow cytometry to unravel the molecular mechanisms underpinning the licensing checkpoint and to define the core molecular pathways that coordinate DNA replication and the cell cycle. A comparison of the effect of ORC and MCM mutations in clinically-relevant cells derived from iPSCs and in cancer cell lines will allow me to understand cell-type specific differences in regulation of DNA replication and explain the effects of these mutations on human patients. These new results will open new possibilities to develop specific anti-cancer drugs against selected components of the licensing checkpoint system. Moreover, it will allow me to merge neurodevelopment, DNA replication, stem cell biology and cancer research, laying the foundations upon which to build my future career.", "To": ["2019-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["746908"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSIDAD PABLO DE OLAVIDE"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["On the Frontiers of Peace. Cross-cultural Peacebuilding on the Global Frontiers of the Iberian Empires (1500-1580)"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["FRONTIERPEACE"], "Technology_Description": "This research project investigates the historical roots of cross-cultural peacebuilding. European expansion during the sixteenth century was characterised by a high degree of violence, which was fuelled by cultural differences and religious radicalisms. The meeting of different cultures created new forms of violence, but, at the same time, generated new forms of cross-cultural encounters that were driven to construct a lasting peace. This project explains the transition from the violent conflicts of the first encounters between Europeans and non-European peoples, to their peaceful coexistence. Rather than focusing on cross-cultural diplomacy or treaty-making, this research project explains how peace was constructed \u201con the ground\u201d. In order to do so, it focuses on three different frontiers of the first global empires. ", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["748592"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["BOURNEMOUTH UNIVERSITY"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Artistic Animation Rendering with Stylization"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["AniStyle"], "Technology_Description": "Computer animation is a key technology for the creative industries and has strong links to many key sectors of digital economy, including gaming and post-production. Its annual global market value is \u20ac200 billion and it is growing 7% annually. Although the European Commission has established policies and initiatives for creative industries, 60% of the global animation market is shared between the US (supported by strong finance and advanced technology) and the Asia-Pacific countries (bolstered by low labour costs). To gain market share in computer animation, the EU needs novel technologies that can produce rich content and special effects at a competitive price. This fellowship project describes how novel Animation Stylization Techniques (ASTs) can be developed to enrich content without high labour costs, by bringing to the UK a high calibre researcher with 9 patents and 28 publications.", "To": ["2019-10-19, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-20"], "Project_ID": ["747439"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["MEDIZINISCHE UNIVERSITAET WIEN"], "EU_Contribution": ["EUR 178 156,80"], "Project_Title": ["Learning and PREdiction based on the PREnatal CONnectome FInGerprint"], "Total_Cost": ["EUR 178 156,80"], "Country": ["Austria"], "Project_ACR": ["PRECONFIG"], "Technology_Description": "\"Endeavours towards a more profound understanding of the neural architecture enabling the staggering cognitive abilities of the human brain hold high promises regarding diagnosis and treatment of various diseases affecting the neural system. The novel paradigm of brain connectomics has opened a wealth of insights into the individual differences, emergence, development, plasticity and disease specific re-organization of macro-scale brain networks composed by interconnected and synchronously operating neural units.", "To": ["2020-11-22, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-11-23"], "Project_ID": ["747831"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITEIT UTRECHT"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["Novel multivariate, high-resolution mapping of the exposure of ecosystems to climate and land use change"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["CLIMLAN"], "Technology_Description": "To protect and preserve natural habitats, we urgently need integrated assessment methodologies. Current conservation-oriented assessments of ecological vulnerability rely upon the identification and quantification of the effects from of the most important drivers of change. However, accurate predictions and practical solutions have proved difficult to formulate as most works at global or continental scales have only focused on climatic changes, disregarding important factors such as land use change. CLIMLAN will address this shortcoming using an integrated assessment that combines two of the most important drivers of biodiversity change today: climate and land-use change. Here I will answer two original and important questions: (1) which are the most useful indices for measuring and mapping the ecological vulnerability to future environmental change?; and (2) is there a mismatch between current management and planning strategies and ecological vulnerability to projected environmental changes? For this, I will focus on measuring and mapping both climate and land use changes over time, and assessing how such changes match both ecosystem vulnerability and current conservation practices. A lasting product of CLIMLAN will be a readily applicable open access spatially explicit methodology and an online mapping tool, to measure and spatially display ecosystem vulnerability to environmental changes. These tools will allow a better assessment of the current and expected effects of changing environmental conditions on conservation areas, and will facilitate targeted management guidelines and improved adaptation strategies.", "To": ["2020-04-01, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-04-02"], "Project_ID": ["748753"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["How visual perception shapes our cities: a cognitive model of ageing population"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["AgeCogCity"], "Technology_Description": "Two mega-trends \u2013 the rapid urbanisation of the world\u2019s population and the ageing of that same population \u2013 will soon collide. Adapting to the challenges of elderly citizens (many of whom no longer drive), urban designers need appropriate tools to support planning for walking, the most environmentally, socially, and economically sustainable transport mode. Cities\u2019 walkability depends not only on physical settings, but also on processes of human spatial cognition, in particular visual perception. However, current state of art methods in modelling and forecasting urban systems are based mainly on economic and transportation demands and ignore pedestrians\u2019 spatial cognition. This research discovers how visuo-spatial cognition contributes to the generation of new urban uses and activities based on the age profile of the user population. It constructs a novel urban-behavioural paradigm that links built environment and the way people use it, by addressing three fundamental questions: (1) What are the most important visuo-spatial properties influencing pedestrian cognition? (2) How urban visibility could be encoded and analysed as an abstracted spatial representation (visibility network)? (3) What mechanisms allow cities to be generated through feedback reflected in pedestrian movement and urban visibility? These questions are answered using an interdisciplinary approach: It combines quantitative techniques for spatial modelling with qualitative strategies for tracing of pedestrian behaviour in Immersive Virtual Reality (IVR). The research findings will set a framework for the evidence-based tool to assist planners, architects and stakeholders in the design and evaluation of urban projects in view of the changing needs of urban population.", "To": ["2020-09-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-10-01"], "Project_ID": ["744835"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Exact Results in Extended Holography"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ERIEH"], "Technology_Description": "The study of integrable models in the AdS/CFT correspondence has provided deep insights into string theory, the holographic principle, and the finite coupling behavior of quantum field theory. My proposal aims to extend aspects of this approach beyond supersymmetric and conformal theories by studying integrable deformations of the AdS5 x S5 superstring. These come in two types \u2014 quantum deformations and Drinfeld twists \u2014 which can produce both new theories and new perspectives on well-established ones. The aims of this programme are (A) to understand quantum deformations in string theory and AdS/CFT, (B) to refine associated technical tools based on integrability, (C) to develop a unified perspective on Drinfeld twists in string theory and AdS/CFT, and (D) to overcome technical obstacles in the integrability based description of twisted models. By developing exact results and methods, this programme will lead to new insights in string theory, holography, and quantum field theory, at finite coupling, beyond the superconformal regime.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["744150"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN"], "EU_Contribution": ["EUR 175 866"], "Project_Title": ["Nanoparticle Biointerface Mapping"], "Total_Cost": ["EUR 175 866"], "Country": ["Ireland"], "Project_ACR": ["NanoBioMap"], "Technology_Description": "The Nanoparticle Biointerface Mapping project builds on the extensive bionano interactions research in the group of Professor Kenneth Dawson at University College Dublin. In the NanoBioMap project I propose a cutting-edge interdisciplinary approach to develop a versatile tool allowing me to obtain detailed 3D maps of biomolecules at the surface of nanoparticles in complex biological media and study their importance for cell interactions. I will build on my extensive knowledge of nanomaterial science to develop this 3D mapping tool combining a tailor-made library of antibody-tagged quantum dots with electron microscopy 3D image reconstruction and X-ray elemental mapping. The resulting versatile method has multiple uses far beyond analyzing protein coronas. I envision applications of this state-of-the-art mapping tool in areas such as vaccine development, enzymatic catalysis on supported particles, cancer treatment and tracking of pollutants in water flows. ", "To": ["2020-09-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-10-01"], "Project_ID": ["743605"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 212 194,80"], "Project_Title": ["Land Use and Climate Change Attribution for biodiversity impact assessments"], "Total_Cost": ["EUR 212 194,80"], "Country": ["Denmark"], "Project_ACR": ["LUCCA"], "Technology_Description": "Across the globe, species are shifting their distributions to track the warming temperatures, and habitat conversion is reducing species diversity. However, while both climate and land use change are recognized as top threats to biodiversity, studies on their synergistic effects are very rare. This is at least partly due to 1) a lack of consistent definitions and measures of land use change that can be directly related to biodiversity responses, and 2) difficulties in attributing change to either driver because of correlations, scale-dependencies, and interaction effects between the two. This project will develop a framework for separating the effects of land use and climate change on biodiversity using a range of methodologies such as meta-analysis, fieldwork, and modeling. The project will assess the land use definition and driver attribution challenges in the past literature, explore the potential of high-resolution remote sensing products and Google Street View to measure land use changes, and use unprecedented long-term monitoring citizen science programs to disentangle impacts of land use and climate change on bird populations as a case study. The Fellowship is a timely answer to recent calls to account for multiple environmental change drivers and improve our predictive ability of future biodiversity changes. The outputs will be of relevance for conservation management and policymaking in the EU and beyond. The host institute (CMEC) is at the forefront of macroecology and climate change research, and will give me access to worldwide experts in areas directly relevant to the project. The research and training opportunities offered by CMEC will broaden my field of study and strengthen my analytical and teaching skills \u2013 crucial for helping me establish an independent research career and become a leading figure within the field of integrative global change ecology in Europe.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["746334"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Nitric oxide regulation of repolarisation in the heart: role of mechanical stress"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["NO-STRESS"], "Technology_Description": "Atrial fibrillation (AF) is a leading risk factor for stroke and is a growing public health burden. The condition is associated with pronounced electrical remodelling of the atria and can prove challenging to treat. A potential target for AF therapies is the repolarising potassium current IKur, carried by the atrial specific ion channel Kv1.5. This channel is not found in the ventricles and therefore provides an attractive therapeutic target for the treatment of AF. In atrial myocytes isolated from patients in AF we have shown an increase in IKur, as well as a reduction in the expression of neuronal nitric oxide synthase (nNOS). Inhibition of nNOS in mycoytes from patients in sinus rhythm recapitulated the AF phenotype. Kv1.5 is also modulated by mechanical stress, which has been shown to affect NO production in myocytes. We have shown that shear stress recruits Kv1.5 from an intracellular pool to the cell surface, leading to an increase in IKur. This proposal aims to investigate mechanism by which nNOS regulates IKur. We hypothesise that mechanical stress (likely modified in AF) will result in altered nNOS regulation of Kv1.5 in human myocytes. We will go on to investigate how nNOS regulation of Kv1.5 is dysregulated in AF. A multi-disciplinary approach will be used employing a) human mycoytes isolated from patients, b) an nNOS knockout (-/-) mouse and c) cardiomycoytes overexpressing GFP-Kv1.5. Whole cell currents from isolated myocytes will be measured electrophysiologically, and IKur pharmacologically dissected. A range of biochemical techniques will be employed to investigate the physical interactions between nNOS and Kv1.5. Conventional and TIRF microscopy will be used to examine the localisation of Kv1.5 and partner proteins when nNOS activity is inhibited, or where the nNOS protein is absent (nNOS-/-). This translational study will improve our understanding of ion channel regulation in AF and may identify important new targets for AF therapies.", "To": ["2020-10-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-10-31"], "Project_ID": ["746208"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Effect of rare-earth doping elements on the mechanical and oxidation resistance performance of silicon carbide coated carbon fibre / zirconium carbide composites for high temperature applications"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["EREMOZ"], "Technology_Description": "There is an increased demand for high temperature structural materials suitable for use at>1400\u00b0C, including heat exchangers, Generation IV nuclear reactor components (e.g. control rod sheath & fuel constituents), the receiver materials of concentrated solar power (CSP) systems, high temperature thermoelectric devices and static components in gas turbines and aero engines. Ultra-high temperature ceramics (UHTCs) exhibit especially high melting temperatures and include the diborides and carbides of zirconium and hafnium (ZrC & HfC). Unfortunately, UHTCs also suffer from poor fracture toughness, relatively poor oxidation resistance and are very difficult to process since the densification temperature required is also very high. EREMOZ will address these challenges by using a non-conventional process route along with a combination of fibre reinforcement and rare earth dopants. Specifically, processing will be based on the energy efficient process of chemical vapour infiltration (CVI) rather than more conventional sintering; the former allows dense composites to be produced at much lower temperatures. The poor fracture toughness will be improved by the introduction of silicon carbide fibres (SiCf) or carbon fibres (Cf), which enhance resistance to crack propagation. Finally, oxidation resistance will be improved by the introduction of second phases, such as those based on silicon and/or rare earths, which facilitate the formation of oxide scales that inhibit oxygen diffusion. The outcomes from this project will be three fold, to: ", "To": ["2020-03-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-04-01"], "Project_ID": ["748568"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF GLASGOW"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["INtelligeNt ApplicatiOns oVer Large ScAle DaTa StrEams"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["INNOVATE"], "Technology_Description": "Large scale data analytics is the key research domain for future data driven applications as numerous of devices produce huge volumes of data in the form of streams. Analytics services can offer the necessary basis for building intelligent decision making mechanisms to support novel applications. Due to the huge volumes of data, analytics should be based on efficient schemes for querying large scale data partitions. Partitions contain only a piece of data and a dedicated processor manages the incoming queries. The management of continuous queries over data streams is a challenging research issue requiring intelligent methods to derive the final outcome (i.e., query response) in limited time with maximum performance. The management process of continuous queries involves their assignment to specific processors and the processing of the derived responses. We focus on a group of query controllers serving the incoming queries and, thus, becoming the connection of big data systems with the real world. INNOVATE proposes solutions for the management of the controllers behavior. We propose an intelligent decision making process for each controller in three axes: (i) top-down, by realizing a mechanism that assigns queries to the underlying processors; (ii) bottom-up, by proposing decision making mechanisms for returning responses to users/applications on top of early results; (iii) horizontal, by proposing optimization schemes for queries management. We adopt a pool of learning schemes and an ensemble learning model dealing with how and on which processors each query should be assigned. We also propose specific schemes for combining processors responses. Intelligent and optimization techniques are adopted for the controllers group management. Machine learning, Computational Intelligence and optimization are the key adopted technologies that, when combined, provide efficient solutions to a challenging problem like the support of intelligent analytics over big data streams.", "To": ["2020-03-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-04-01"], "Project_ID": ["745829"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITETET I OSLO"], "EU_Contribution": ["EUR 208 400,40"], "Project_Title": ["Spectra of Molecules in Strong Magnetic Fields"], "Total_Cost": ["EUR 208 400,40"], "Country": ["Norway"], "Project_ACR": ["MAGSPEC"], "Technology_Description": "Electronic spectroscopy is one among several types of spectroscopy employed to study molecules in stellar objects. Strong magnetic fields, as in white-dwarfs and neutron stars, can severely distort these spectra. To accurately interpret the data, we must understand the forces shaping the spectra in situations so far removed from terrestrial conditions. Such strong fields also imply a breakdown of the perturbative mechanism commonly used for studying magnetic phenomena in the pertinent regimes on earth. We shall focus on the intermediate regime of field strengths (~10^5 T), where, neither the magnetic field nor the inter-particle interaction can be treated as a perturbation leading to novel physics and chemistry, that remains little explored for molecules. This project seeks to develop the methodology to compute excitation energies and potential energy surfaces in the presence of strong uniform and non-uniform magnetic fields, included non-perturbatively, at varying levels of theoretical complexity (Hartree-Fock, Density Functional Theory, Random Phase Approximation, SRCC and MRCC) and study the distortion of these spectra across a range of magnetic field strengths. We shall focus on analysing the source of these distortions at the microscopic level, ie. which of orbital effects, spin effects, correlation effects and relativistic effects play the determining role. This project is multidisciplinary using principles of quantum chemistry in tackling astrochemical problems. The study is fundamental and is expected to reveal interesting results relevant even for the weaker fields on earth. The benchmarking of the standard DFT exchange-correlation functionals against CC in the regime of strong magnetic fields will have a long-term impact as most existing DFT approximations have been formulated within DFT or collinear spin DFT (SDFT); practical DFT functionals to describe molecules in magnetic fields (e.g. at the CDFT or non-collinear SDFT level) are much less developed.", "To": ["2020-09-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-10-01"], "Project_ID": ["745336"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["BILKENT UNIVERSITESI VAKIF"], "EU_Contribution": ["EUR 157 845,60"], "Project_Title": ["Nanoscale Vertical Cavity Surface Emitting Laser and its Arrays"], "Total_Cost": ["EUR 157 845,60"], "Country": ["Turkey"], "Project_ACR": ["NOVEL"], "Technology_Description": "Significant advances are needed to improve the speed and efficiency of future communication and computing systems. Photonic interconnect components are the only solution to offer both high speed and low power consumption. To this end, vertical-cavity surface-emitting lasers (VCSELs) have been widely deployed as optical interconnects in the last two decades. Even though the current VCSEL technology has been very successful, its processing approach has been proven to be particularly challenging for miniaturization, it reduces the reliability for small lasers and its high thermal resistance substantially degrades the lasers\u2019 performance. This project addresses all these bottlenecks by focusing on the development of a nanoscale VCSEL (NOVEL) device for ultra-low threshold, energy efficient and ultra-fast operation for future optical interconnects and light sources.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Turkey"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["745598"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Endoplasmic reticulum structure and synaptic function in Drosophila"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SynapseER"], "Technology_Description": "In neurons, endoplasmic reticulum (ER) organelle shows physical continuity between dendrites, cell body and axonal presynaptic terminals, and has been termed \u201ca neuron within a neuron\u201d. The importance of ER in axons is suggested by the fact that mutations of ER-shaping proteins result in hereditary spastic paraplegia (HSP), a motor axon degeneration disease. ER is present in presynapses, and mutations of ER-shaping proteins disrupt synaptic morphology or function. However, the physiological roles of ER distribution in this context are largely unknown.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["745007"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAT DE BARCELONA", "UNIVERSITAT DE BARCELONA"], "EU_Contribution": ["EUR 2 199 318"], "Project_Title": ["Moments in Time in Immersive Virtual Environments"], "Total_Cost": ["EUR 2 199 318"], "Country": ["Spain", "Spain"], "Project_ACR": ["MoTIVE"], "Technology_Description": "This project investigates how virtual reality (VR) can be used to live through an historical event so that participants perceive themselves to be there (Place Illusion) and take the events that are happening as real (Plausibility). To provide an application focus the research will be constructed around recreating a famous rock concert from the 1980s. The specific elements of the research involve an Agent Based Model (ABM) that populates the environment with thousands of virtual characters with their behaviour driven by the music. This ABM will run in VR embedding participants as a type of agent. Agents will have personality and emotional state that can influence one another, and the actions and state of participants will also influence the unfolding of the model. Based on the predictive coding model of brain functioning a theory of Place Illusion will be developed that results in a universal measurement. Similarly, the Plausibility Illusion will be modelled and corresponding universal measure derived. Participants in VR will be embodied, so that they will have a first person perspective life-sized virtual body that moves as they do. We will exploit the concept of body ownership and its consequences for attitudinal, behavioural, cognitive and agency changes to give people unique experiences of the virtual events, and carry out a series of experiments to assess the influence of being transported back in time in a younger body has on ageing. Our recent discovery that illusory agency can be realised through virtual embodiment will be used for research on improved motor learning. To allow people to move through the environment we will investigate paradigms for virtual walking, and in particular whether the multisensory principles involved in body ownership illusions can be used to lessen simulator sickness. The long term goal of the project is to understand how to capture treasured past moments lost in time, through their reproduction in ABM inspired virtual reality.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["742989"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["KAROLINSKA INSTITUTET", "KAROLINSKA INSTITUTET"], "EU_Contribution": ["EUR 2 149 227,50"], "Project_Title": ["A Functional, Mature In vivo Human Ventricular Muscle Patch for Cardiomyopathy"], "Total_Cost": ["EUR 2 149 227,50"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["5D Heart Patch"], "Technology_Description": "Developing new therapeutic strategies for heart regeneration is a major goal for cardiac biology and medicine. While cardiomyocytes can be generated from human pluripotent stem (hPSC) cells in vitro, it has proven difficult to use these cells to generate a large scale, mature human heart ventricular muscle graft on the injured heart in vivo. The central objective of this proposal is to optimize the generation of a large-scale pure, fully functional human ventricular muscle patch in vivo through the self-assembly of purified human ventricular progenitors and the localized expression of defined paracrine factors that drive their expansion, differentiation, vascularization, matrix formation, and maturation. Recently, we have found that purified hPSC-derived ventricular progenitors (HVPs) can self-assemble in vivo on the epicardial surface into a 3D vascularized, and functional ventricular patch with its own extracellular matrix via a cell autonomous pathway. A two-step protocol and FACS purification of HVP receptors can generate billions of pure HVPs- The current proposal will lead to the identification of defined paracrine pathways to enhance the survival, grafting/implantation, expansion, differentiation, matrix formation, vascularization and maturation of the graft in vivo. We will captalize on our unique HVP system and our novel modRNA technology to deliver therapeutic strategies by using the in vivo human ventricular muscle to model in vivo arrhythmogenic cardiomyopathy, and optimize the ability of the graft to compensate for the massive loss of functional muscle during ischemic cardiomyopathy and post-myocardial infarction. The studies will lead to new in vivo chimeric models of human cardiac disease and an experimental paradigm to optimize organ-on-organ cardiac tissue engineers of an in vivo, functional mature ventricular patch for cardiomyopathy", "To": ["2022-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["743225"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERZA V LJUBLJANI", "UNIVERZA V LJUBLJANI"], "EU_Contribution": ["EUR 2 266 067"], "Project_Title": ["Post-war trasistions in gendered perspective: the case of the North-Eastern Adricatic Region"], "Total_Cost": ["EUR 2 266 067"], "Country": ["Slovenia", "Slovenia"], "Project_ACR": ["EIRENE"], "Technology_Description": "The EIRENE project\u2019s purpose is to think afresh 20th-century post-war transitions by taking into account a gendered perspective. Namely, the historiographic consideration of gender thoroughly alters the understanding of social dynamics in multi-ethnic areas during the post-war transitions. They will be observed in the North-Eastern Adriatic region, an overlooked European space, marked by border redefinitions, changes of political systems, and high interethnic conflict intensity, but also by genuine cooperation among ethnic groups. The region has all the qualities of a \u201claboratory environment\u201d for the study of gender positions and interrelations after World Wars I and II and after the Yugoslav wars in the 1990s. The project will differ substantially from previous attempts to analyse post-war transitions in these aspects: a) longitudinal approach, comparing three post-war periods in order to detect their specifics and (dis)continuities; b) transnational approach, by overcoming nation-centric frameworks of analysis; c) by combining conceptual political and social sciences with historiography; and finally, d) by examining post-war transitions through the prism of gender. Focusing on four research-fields (politics, political violence, work, family), the project will validate innovative analytical concepts of the \u201cinclusion-exclusion paradox\u201d of women in post-war transitions, and women as \u201ccross-boundary mediators\u201d. Within the category of gender, focal attention will be given to women as they are often invisible in historical accounts and remain neglected in historicizing. By aggregating empirical sources, the project will approach the proposed subject matter by investigating the processes of identification across the lines of ethnic origin, class, generations, marital status, profession/occupation, language of use, migratory processes, etc. The project\u2019s added value is its novel conceptual applicability to other comparable geopolitical areas.", "To": ["2022-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Slovenia"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["742683"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 200 194,80"], "Project_Title": ["Structure and classification of C*-dynamics"], "Total_Cost": ["EUR 200 194,80"], "Country": ["Denmark"], "Project_ACR": ["SCCD"], "Technology_Description": "We study group actions on C*-algebras from a structure and classification point of view, importing concepts from the Elliott classification program into the equivariant context. The challenge is to advance the structure theory for natural classes of actions of amenable groups on C*-algebras. In a similar vein, we shall consider flows on C*-algebras, which are the mathematical abstractions of time evolutions. The objectives of this proposal are:", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["746272"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM", "UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 2 498 328"], "Project_Title": ["Understanding the Stability and Plasticity of Emotional Memory"], "Total_Cost": ["EUR 2 498 328"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["ErasingFear"], "Technology_Description": "The breakthrough discovery in animal research that fear memories may change upon retrieval \u2013 referred to as memory reconsolidation \u2013 has drastically changed the view on the malleability of emotional memory. Inspired by these insights, we have developed a novel approach to pharmacologically erase the affective component from fear memories in humans. Although these findings suggest a paradigm shift in clinical practice, there are many fundamental questions to be resolved.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["743263"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI MILANO", "UNIVERSITA DEGLI STUDI DI MILANO", "FONDAZIONE ISTITUTO NAZIONALE DI GENETICA MOLECOLARE INGM"], "EU_Contribution": ["EUR 2 040 943"], "Project_Title": ["HD-DittoGraph: a digital human Embryonic Stem Cell platform for Huntington's repeats"], "Total_Cost": ["EUR 2 040 943"], "Country": ["Italy", "Italy", "Italy"], "Project_ACR": ["HD-DittoGraph"], "Technology_Description": "This proposal is aimed at identifying the molecular mechanisms that have brought the human Huntington Disease-causing Huntingtin (Htt) exon 1, with its pure and unstable CAG repeat, to be shaped the way it is today. Specifically, we intend to screen for genetic elements affecting Htt repeat length instability in dividing and postmitotic neuronal cells. The novelty of our approach relies on the construction of a human embryonic stem (hES) cell platform that couples highly efficient CRISPR/Cas9 technology with genome-wide screenings and third generation sequencing, to test the contribution of thousands of unequivocally barcoded cis and trans modifiers on Htt exon 1 repeats instability. ", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2018-03-01"], "Project_ID": ["742436"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["ECOLE D'ECONOMIE DE PARIS", "ECOLE D'ECONOMIE DE PARIS", "UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 1 523 217"], "Project_Title": ["Learning through Categories in Social and Economic Interactions"], "Total_Cost": ["EUR 1 523 217,01"], "Country": ["France", "France", "United Kingdom"], "Project_ACR": ["LTCSEI"], "Technology_Description": "The analogy-based expectation equilibrium (Jehiel, 2005) has been introduced to cope with strategic environments in which agents form their expectations by bundling data that come from different sources (see also the valuation equilibrium defined in Jehiel and Samet, 2007). An essential next step is to make progress on when and how subjects bundle data to facilitate learning. Various principles are proposed to discipline the choices of analogy partitions in ABEE and of similarity classes in VE: the observation-based principle views the bundling as a consequence of a lack of accessibility to missing information in past interactions, the psychologically-based principle views categorizations as the consequence of observed similarity in early interactions, the culturally-based principle views the bundling of actions into similarity classes either as a consequence of a common labelling of actions or as a consequence of ethical considerations that lead us to think of different actions as having similar consequences. The impact of such principles will be studied both theoretically and experimentally with the goals of explaining a number of new phenomena and shifting the conventional wisdom in behavioural economics that has pointed out a number of anomalies in behaviors without systematically relating them to imperfections in the learning process. In addition, I will be concerned with the aggregation of different types of feedback such as data on one own performance or data on others\u2019 attitudes in multi-context environments, as well as putting the proposed approach of learning through categories in the broader perspective of the literature on bounded rationality", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["742816"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS", "STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS"], "EU_Contribution": ["EUR 2 405 625"], "Project_Title": ["Sensitivity of human tumors to T cell attack"], "Total_Cost": ["EUR 2 405 625"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["SENSIT"], "Technology_Description": "The goal of this project is to describe the tumor cell-intrinsic mechanisms that determine whether \u2018foreign\u2019 human cancers are sensitive or resistant to the tumor-specific T cell response they induce. In this effort, I will focus on 3 linked questions: ", "To": ["2022-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-12-01"], "Project_ID": ["742259"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSIDAD POMPEU FABRA", "UNIVERSIDAD POMPEU FABRA"], "EU_Contribution": ["EUR 2 343 249"], "Project_Title": ["Transnational Gangs as Agents of Mediation: Experiences of Conflict Resolution in Street Youth Organizations in Southern Europe, North Africa and the Americas"], "Total_Cost": ["EUR 2 343 249"], "Country": ["Spain", "Spain"], "Project_ACR": ["TRANSGANG"], "Technology_Description": "TRANSGANG aims to develop a renewed model for the analysis of transnational youth gangs in the global age, in dialogue with two classics of urban ethnography, published nearly a century ago: The Gang, by F.M. Thrasher (1926) and The Polish Peasant in Europe and America, by W. I. Thomas and F. Znaniecki (1918-1920). To do this, the project will start by a systematic review of the historical literature on youth gangs, which will try to overcome the north-american-centrism, dominant in contemporary criminology. The central phase of the research will focus on a multisited and multilevel ethnography that will explore experiences in which gangs have acted as agents of mediation, as well as the barriers that have blocked these attempts. The project will compare street youth organizations from two transnational communities -Latinos and Arabs-, both in their homelands and in their new European neigbourhoods. Starting with three case studies of \u201cgood practices\u201d in Barcelona, Medellin and Casablanca, which will be studied in depth, contrasts with other cases in which other policies have been implemented will be established: Madrid, Marseille and Milan in southern Europe; Oran Tunis and Cairo in north Africa; Chicago, Santiago de Cuba and San Salvador in the Americas. Using an experimental approach based on the \u201cextended case method\u201d, it will have as its theme the making of a film that collects the experience of members or former members of gangs who have participated in mediation experiences. The ultimate goal is to develop a renewed transnational, inter-generational, intergeneric and transmedia approach to Twenty-First-century gangs, very different from the local, coeval, male and face-to-face model used for understanding gangs in the Twentieth century. Although the focus of the project is theoretical, its purpose is applied: to deduce more effective ways of intervention to prevent the hegemony of the criminal gang model that appears as dominant in the neoliberal era.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["742705"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE", "LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE"], "EU_Contribution": ["EUR 1 932 655,01"], "Project_Title": ["Man and Nature in Developing Countries"], "Total_Cost": ["EUR 1 932 655,01"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["MANANDNATURE"], "Technology_Description": "The growth required to lift a billion people out of extreme poverty will require large increases in natural resource extraction and energy consumption. The negative externalities this growth creates \u2013 through degradation of forests and oceans, pollution and climate change \u2013 will affect us all. This is a proposal to create a new body of research on natural resource management and energy use in developing countries. It is distinctive for four reasons. First, it brings novel, applied micro techniques from development economics to the study of environmental and energy economics. Second, it harnesses new data collection technologies using satellites and randomized control trials. Third, we pioneer the use of political economy approaches to understand the gap between de jure and de facto policies. Finally, we innovate on policy design by embedding researchers with policy partners to co-generate research and ensure that findings scale directly into policies.", "To": ["2022-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["743278"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "ACADEMISCH ZIEKENHUIS LEIDEN"], "EU_Contribution": ["EUR 2 500 000"], "Project_Title": ["Developing Geroprotectors to Prevent Polymorbidity"], "Total_Cost": ["EUR 2 500 000"], "Country": ["Germany", "Germany", "Netherlands"], "Project_ACR": ["GeroProtect"], "Technology_Description": "Advancing age is the major risk factor for disability and illness, including cardiovascular, metabolic and neu-rodegenerative disease and cancer. The increasing incidence of older people in European countries is posing major medical, social and economic challenges, and there is an urgent need to find ways of compressing late-life morbidity. Ageing has proved malleable to genetic and pharmacological interventions in laboratory animals, and at least some of the mechanisms are conserved over large evolutionary distances. Reduced activity of the nutrient-sensing insulin/insulin-like growth factor/TOR signalling network can increase health and combat ageing-related disease in laboratory animals, with increasing evidence of its importance in human ageing. There is thus a prospect for pharmacological intervention to prevent more than one ageing-related condition, rather than tackling diseases one by one and as they arise. The aim of this research programme is to evaluate the potential for pharmacological prevention of ageing-related decline in humans with a polypill targeting the nutrient-sensing network. We find that three licensed drugs, lithium, rapamycin and trametinib, act independently, at different nodes in the network, to increase lifespan in the fruitfly Drosophila, implying that the network controls more than one underlying mechanism of ageing, and that a polypill of these drugs could be particularly effective. We shall test this idea in mice, and assess the underlying mechanisms in Drosophila and mice. We have found that suppression of the Ras signalling branch of the network, which has a well known role in human cancer, can extend lifespan in both the fruitfly Drosophila and mice, and we shall assess its role in humans. Interventions that ameliorate ageing often have sex-specific effects, and we shall investigate the mechanisms leading to these for the nutrient-sensing network. The outputs of the work will inform future clinical trails in humans.", "To": ["2022-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["741989"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITAET ZU KOELN", "UNIVERSITAET ZU KOELN", "THE REGENTS OF THE UNIVERSITY OF CALIFORNIA"], "EU_Contribution": ["EUR 1 155 104"], "Project_Title": ["Economic Engineering of Cooperation in Modern Markets"], "Total_Cost": ["EUR 1 155 104,01"], "Country": ["Germany", "Germany", "United States"], "Project_ACR": ["EEC"], "Technology_Description": "Cooperation is essential for the functioning of the economy and society. Thus, with inappropriate mechanisms to harness self-interest by aligning it with the common good, the outcome of social and economic interaction can be bleak and even catastrophic. ", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["741409"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["AARHUS UNIVERSITET", "AARHUS UNIVERSITET"], "EU_Contribution": ["EUR 2 398 993"], "Project_Title": ["Common Interactive Objects"], "Total_Cost": ["EUR 2 398 993,01"], "Country": ["Denmark", "Denmark"], "Project_ACR": ["CIO"], "Technology_Description": "In CIO, common interactive objects are developed and explored to extend human control over the technological environment by human beings, both individually and together. CIO leads to a coherent framework of user interfaces to be applied in interaction design. Common interactive objects will provide a useful frame for furthering human computer interaction (HCI) theory, development of interaction design methods and the underlying technical platforms. Common interactive objects will empower users to better understand and develop the technologies they use. ", "To": ["2022-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["740548"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["STOCKHOLMS UNIVERSITET", "STOCKHOLMS UNIVERSITET"], "EU_Contribution": ["EUR 1 716 970"], "Project_Title": ["Social Media and Traditional Media in China: Political and Economic Effects"], "Total_Cost": ["EUR 1 716 970"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["MEDIACHINA"], "Technology_Description": "How is political accountability and firm performance in an autocracy affected by media? This project will analyse how economic and political outcomes in China are affected by social and traditional media. It will also use media content to measure factors that are otherwise difficult to observe, such as political networks and the trade-off between political and economic goals in Chinese firms. An explosion of social media use in China has produced an information shock to society and its leaders, also supplying a data shock to researchers, which is magnified by the digitization of traditional media content, and coupled with new methods for analysing this type of data, originating from the in big data and machine-learning literatures. As a result, a large set of previously unanswerable questions are now open for research.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["742983"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITEIT MAASTRICHT", "UNIVERSITEIT MAASTRICHT", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.", "MUCKE HERMANN"], "EU_Contribution": ["EUR 149 993,71"], "Project_Title": ["Proof of principle for a first in class neuroprotective therapy in stroke and other acute neurodegenerative conditions"], "Total_Cost": ["EUR 149 993,71"], "Country": ["Netherlands", "Netherlands", "Germany", "Austria"], "Project_ACR": ["SAVEBRAIN"], "Technology_Description": "Stroke represents currently one of the largest \u2013 if not the largest - unmet medical need: It is the second leading cause of death and the leading cause of disability. In contrast to this high demand for effective treatments, there is only one drug available, a blood-clot dissolving agent. However, this drug is marginally effective has over 30 contra-indications, and bears an extremely high risk of causing fatal bleeding that 85% of all stroke patients are not treated with it. The needed innovation would be a drug which is broadly applicable, i.e. has no contraindication, can be given in all forms of stroke and already in the ambulance, is safe, i.e. bears no risk to cause secondary bleeding, is effective, i.e. reduces the brain infarct, increases survival and improves neurological outcomes for patients, has a different mechanism of action, i.e. is directly neuroprotective. Our therapeutic principle, discovered in the course of the ERC-ADG RadMed fulfils all above criteria and is also commercially an innovative approach because we reduce the risk by developing only a single compound by here combining three compounds that target the same disease mechanism but at different points. We thereby expect to dramatically reduce the likelihood risk of failure in our post-proof of concept (PoC) clinical development and commercialisation process. We here propose to conduct the final step, the PoC, before a first-in-man study in stroke. Our PoC plan has three major objectives: To complete an IPR FTPO and Foreground analysis, to chose the optimal compounds and complete phase III pre-clinical to provide PoC for a first-in-man trial in stroke, to then allow the work-out of a complete business plan including competitive analysis, development strategy, and commercial/business development strategy.", "To": ["2019-09-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-04-01"], "Project_ID": ["737586"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO SANT'ANNA", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "KARLSRUHER INSTITUT FUER TECHNOLOGIE", "TECHNISCHE UNIVERSITAET MUENCHEN", "FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA", "UNIVERSITEIT TWENTE", "UNIVERSITAT POLITECNICA DE CATALUNYA", "UNIVERSIDAD DE SEVILLA", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "UNIVERSITY OF THE WEST OF ENGLAND, BRISTOL", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "UNIVERZA V LJUBLJANI"], "EU_Contribution": ["EUR 4 999 236,25"], "Project_Title": ["The European Robotics Research Infrastructure Network"], "Total_Cost": ["EUR 4 999 236,25"], "Country": ["Italy", "France", "France", "Germany", "Germany", "Italy", "Netherlands", "Spain", "Spain", "Switzerland", "United Kingdom", "United Kingdom", "Slovenia"], "Project_ACR": ["TERRINet"], "Technology_Description": "After a few decades of intense research and development, Robotics has produced radical innovation and impact in many sectors (manufacturing, space, medicine\u2026). In addition Robotics has generated novel scientific and engineering knowledge. This is due to the unique nature of Robotics, that has evolved from a predominantly engineering-oriented domain, to a transdisciplinary area including and inspiring many different disciplines. Europe is an undisputed leader in Robotics: it has nurtured a large community of researchers, educated many thousand students, created large and small companies, and established advanced facilities for conducting scientific research and contributing to technological innovation. However, despite of significant efforts and achievements, the existing Robotics facilities are not fully synchronized, and lack common procedures, thus hampering their enormous potential for world class research and innovation. Creating a Robotics Research Infrastructure is realistic, timely and essential in the current and future landscape of Robotics. The European Robotics Research Infrastructures Network (TERRINet) project aims at building a world-class network with harmonised services and complementary capabilities where talented researchers from academia and industry worldwide will have access and will be able to explore new ideas and establish personal and joint projects; to get in contact with and be inspired by leading and creative scientists, technologists, experts and industrial representatives; to share information and gain knowledge for boosting their scientific research and potential for technological innovation. The plan of TERRINet is to accomplish its vision by providing not only an organised and well orchestrated set of facilities, but also databases, tools and methodologies which will remain operational after the end of the project, so to provide a long-term service to Robotics science and industry in Europe and worldwide.", "To": ["2021-11-30, ongoing project"], "Meta": [""], "Topic_s": ["INFRAIA-02-2017 - Integrating Activities for Starting Communities"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Chiara Andreoli", "Tel.: +3901071781854", "Fax: +39 010 7170817", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["730994"], "Call_for_Proposal": ["H2020-INFRAIA-2017-1-two-stage"]}, -{"Partners": ["BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Climate monitoring and seasonal forecast for global crop production"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["CLIM4CROP"], "Technology_Description": "When provided in a climate-services context, seasonal climate forecasts can enable a more effective adaptation to climate variability and change, offering an under-exploited opportunity to minimise the agricultural impacts of adverse climate conditions. However, the development of seasonal prediction systems of climate-driven impacts on agriculture is still largely in the early stages, especially on a global scale. CLIM4CROP is designed as a multidisciplinary project aimed at exploring how to best exploit seasonal forecasts for crop management decision making on a global scale. This goal will be achieved through three specific supporting objectives: a) characterising the uncertainties in global datasets of climate observations covering the last three decades and providing data in near-real time; b) understanding the role of climate as underlying mechanisms driving crop yields, and thereby developing statistical models linking climate and yields; c) exploring the seasonal predictability of crop yields with the above-mentioned developed models and implementing a model suite operationally using the data available in near-real time. These objectives will be addressed by making use of the latest advances in climate information, including the most complete and up-to-date sets of seasonal forecast systems. The expected outcomes of this project are an improved understanding of the interaction between climate and crop yields, and new insights allowing more efficient crop management. This could prove useful to policy-makers and commercial entities in their decision-making processes. To this end, the transfer of knowledge to impact users is envisaged.", "To": ["2020-11-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2018-12-01"], "Project_ID": ["740073"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KOZEP-EUROPAI EGYETEM", "KOZEP-EUROPAI EGYETEM"], "EU_Contribution": ["EUR 2 498 748"], "Project_Title": ["Tracking and evaluating social relations and potential partners in infancy"], "Total_Cost": ["EUR 2 498 748"], "Country": ["Hungary", "Hungary"], "Project_ACR": ["PARTNERS"], "Technology_Description": "In order to navigate the social world, children must understand how social interactions unfold in their society. While many recent studies have investigated how children evaluate the roles that people play in everyday interactions and what inferences they draw from their observations, to date there is no unifying account for the conceptual repertoire and computational mechanisms used by infants to analyse their social environment. Taking a new theoretical perspective on this topic, we plan to study whether and how human infants and young children are able to infer the social relations that underlie observed interactions. The theoretical background of this approach is based on the combination of two proposals: (1) that actions are analysed in terms of the costs and benefits they produce to the actors and others affected, and (2) Alan Fiske\u2019s theory, according to which human social relations could be classified into basic elementary forms. Using a variety of behavioural and neuroimaging techniques, we intend to investigate whether children infer the specific social relation that the intentional structure and the cost-benefit outcome of an observed interaction could reveal. More specifically, while resource transfer events (e.g., giving, taking) alter the distribution of goods among participants, they may also cue certain types of underlying relations that would ensure that all parties benefit, directly or indirectly, from the exchange on the long run (e.g., by reciprocity). We aim to establish whether drawing inferences to social relations enjoys the priority in the infant mind over attribution of social dispositions, whether infants predict the outcome of new, previously unobserved interactions, what information children use to choose partners for cooperative tasks, and how they track individuals across social contexts. This research will also provide a new perspective on the development of moral psychology by extending its domain from actions to social interactions.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Hungary"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["742231"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["THE FRANCIS CRICK INSTITUTE LIMITED", "THE FRANCIS CRICK INSTITUTE LIMITED"], "EU_Contribution": ["EUR 2 357 000"], "Project_Title": ["The molecular and cellular logic of vertebrate neural development"], "Total_Cost": ["EUR 2 357 000"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["LogNeuroDev"], "Technology_Description": "A central problem in biology and key to realising the potential of regenerative medicine is understanding the mechanisms that produce and organize cells in the complex tissues of an embryo. In broad terms, initially uncommitted progenitors acquire their fate in response to signals that control transcriptional programmes. These programmes drive cells through spatial and temporal successions of states that gradually refine cell identity. How these states are established and cell fate decisions implemented is poorly understood. To address this we use an experimentally tractable system \u2013 the formation of defined populations of progenitors in the vertebrate spinal cord. We take an interdisciplinary approach that combines our in vivo expertise with three recent advances in our group. First, we have developed in vitro differentiation systems and microfluidic devices that use embryonic stem cells to recapitulate development processes. Second, we have embraced new technologies that provide unprecedented ability to manipulate and assay single cells. Finally, we have established interdisciplinary collaborations to develop computational tools and construct data driven mathematical models. Using these approaches, alongside established embryological methods, we will establish a platform for manipulating and analysing mechanisms by which the multipotent progenitors that form the spinal cord acquire specific identities. We will identify the rules by which cells make decisions and we will define the design logic and network architectures that lead to distinct cell fate choices. The ability to: (i) follow the trajectory of a cell as it transitions to a specific neuronal subtype in vivo; (ii) manipulate the process in vitro and in vivo; and (iii) model it in silico, offers a unique system for understanding organogenesis. Together these approaches will provide the knowledge and technical foundations for rational, predictive tissue engineering of the spinal cord.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["742138"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 2 499 111"], "Project_Title": ["Development of New therapies against cholangiopathies."], "Total_Cost": ["EUR 2 499 111"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["New Chol"], "Technology_Description": "Cholangiopathies represent a diverse group of diseases affecting cholangiocytes which are the main cell type of the biliary tract. These disorders range from inherited (Cystic Fibrosis) and developmental (Alagille Syndrome, Biliary Atresia) to autoimmune (Primary Biliary Cirrhosis), idiopathic (Primary Sclerosing Cholangitis) and drug or toxin induced diseases. Cholangiopathies result in toxic bile accumulation in the liver inducing cell death and ultimately cirrhosis. They carry high morbidity and mortality, accounting for up to a third of chronic liver disorders. Whole liver transplantation remains the main treatment. However, organ transplant requires immunosuppression with significant side effects and an increasing number of patients die while on the transplant list due to the shortage of suitable donors. Finally, the absence of physiologically relevant in vitro systems to model and to study cholangiopathies prevents the development of new therapeutics while cell based therapy approach have been unexplored. Here, we propose to systematically address these challenges by developing a novel and innovative program of translational research focusing on cholangiopathies. We will first investigate the cellular and functional diversity of the biliary tract and its impact on disease by taking advantage of recent developments in single cell transcriptomic analyses. We will then use this basic knowledge to generate and to characterize for the first time a renewable source of cholangiocytes from human induced pluripotent stem cells and from biliary tissue. The resulting cells will be used to model cholangiopathies in vitro and to create a new platform for drug target identification. Finally, we will explore the potential for in vitro generated cholangiocytes to be used in regenerative medicine applications including cell based therapy. Overall this comprehensive program will uniquely path the way for the development of a whole range of new therapies for cholangiopathies.", "To": ["2022-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["741707"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["ALFRED-WEGENER-INSTITUT HELMHOLTZ-ZENTRUM FUR POLAR- UND MEERESFORSCHUNG", "POLARFORSKNINGSSEKRETARIETET", "NORSK POLARINSTITUTT", "UNIVERSITE LAVAL", "University of Alaska", "NORDURSLODAGATTIN EHF", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "CONSIGLIO NAZIONALE DELLE RICERCHE", "WOC - WORLD OCEAN LIMITED", "INSTYTUT OCEANOLOGII POLSKIEJ AKADEMII NAUK", "ILMATIETEEN LAITOS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "NATURAL ENVIRONMENT RESEARCH COUNCIL", "DANMARKS TEKNISKE UNIVERSITET"], "EU_Contribution": ["EUR 5 996 563,75"], "Project_Title": ["Arctic Research Icebreaker Consortium: A strategy for meeting the needs for marine-based research in the Arctic"], "Total_Cost": ["EUR 5 996 567,50"], "Country": ["Germany", "Sweden", "Norway", "Canada", "United States", "Iceland", "Spain", "Italy", "United Kingdom", "Poland", "Finland", "France", "United Kingdom", "Denmark"], "Project_ACR": ["ARICE"], "Technology_Description": "The recent changes of the Arctic and the increased economic activity in the region have triggered a demand for accurate sea-ice and weather predictions, for information on the status of the Arctic Ocean, and for complex predictions of future scenarios. To address these issues of particular environmental and societal concern and to develop policy recommendations for a sustainable usage of the Arctic Ocean and its resources, the Arctic science community needs world-class research icebreakers (RIs) to access the ice-covered Arctic Ocean. The current shortage of availability of RIs and a not optimally coordinated polar research fleet impedes Europe\u2019s capacity to investigate this region. There is thus an urgent need for providing European researchers with better RI capacities for the Arctic. ARICE aims at reaching this goal with the existing polar fleet by:", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["INFRAIA-02-2017 - Integrating Activities for Starting Communities"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Other", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["730965"], "Call_for_Proposal": ["H2020-INFRAIA-2017-1-two-stage"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI TORINO", "KATHOLIEKE UNIVERSITEIT LEUVEN", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "INSTITUT CURIE", "FUNDACIO PRIVADA INSTITUT D'INVESTIGACIO ONCOLOGICA DE VALL-HEBRON", "STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS", "Masarykova univerzita", "EUROPEAN MOLECULAR BIOLOGY LABORATORY", "BIOBANKS AND BIOMOLECULAR RESOURCES RESEARCH INFRASTRUCTURE CONSORTIUM (BBMRI-ERIC)", "ROYAL COLLEGE OF SURGEONS IN IRELAND", "INSTITUT CATALA D'ONCOLOGIA", "THE UNIVERSITY OF MANCHESTER", "ACADEMISCH ZIEKENHUIS GRONINGEN", "OSLO UNIVERSITETSSYKEHUS HF", "ISTITUTO EUROPEO DI ONCOLOGIA SRL", "HOSPITAL UNIVERSITARIO DE FUENLABRADA", "KAIROS3D SRL", "OCELLO BV", "SEEDING SCIENCE"], "EU_Contribution": ["EUR 5 156 198,75"], "Project_Title": ["EurOPDX Distributed Infrastructure for Research on patient-derived cancer Xenografts"], "Total_Cost": ["EUR 5 156 198,75"], "Country": ["Italy", "Belgium", "United Kingdom", "France", "Spain", "Netherlands", "Czech Republic", "Germany", "Austria", "Ireland", "Spain", "United Kingdom", "Netherlands", "Norway", "Italy", "Spain", "Italy", "Netherlands", "France"], "Project_ACR": ["EDIReX"], "Technology_Description": "Counteracting high attrition rates in oncology drug development and providing optimal therapeutic management of cancer patients require preclinical models that properly recapitulate the complexity and diversity of human tumours. Patient-derived tumour xenografts (PDXs), established by transplanting tumour fragments into immunodeficient mice, are being widely embraced by the scientific community as preclinical tools for target and biomarker discovery. The overall goal of EDIReX is to establish a cutting-edge European infrastructure offering Trans-national Access (TA) of PDX resources to academic and industrial cancer researchers, including the distribution of cryopreserved samples to third parties, the structured biobanking of user-developed models, and the performance of efficacy studies. To ensure interoperability in services, TA initiatives will be backed by Networking Activities (NAs); these will be mainly centred around the establishment of standard procedures for PDX quality control, long-term storage and therapeutic mouse trials. NAs will also entail the adoption of shared ethics parameters for animal experimentation, the wide dissemination of services and project results, and the design of plans to ensure sustainability of the infrastructure. User outreach will be maximised by Joint Research Activities through a three-pronged approach: i) the implementation of a public Data Portal for efficient and user-friendly query and visualisation of clinical, molecular and pharmacological annotation of the models; ii) a cross-validation mouse trial to harmonise inter-laboratory procedures, thus improving the quality and reliability of service provision; and iii) the development of exploratory, more advanced PDX-based preclinical platforms, such as orthotopic and humanised models and in vitro PDX-derived cells. Capitalising on all these assets, EDIReX will contribute to structuring the European Research Area and global cooperation of research infrastructures.", "To": ["2022-01-31, ongoing project"], "Meta": [""], "Topic_s": ["INFRAIA-02-2017 - Integrating Activities for Starting Communities"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-02-01"], "Project_ID": ["731105"], "Call_for_Proposal": ["H2020-INFRAIA-2017-1-two-stage"]}, -{"Partners": ["UNIVERSIDADE DO PORTO", "UNIVERSITAET BREMEN", "ASSOCIACAO DO INSTITUTO SUPERIOR TECNICO PARA A INVESTIGACAO E DESENVOLVIMENTO", "UNIVERSITA DEGLI STUDI DI GENOVA", "SVEUCILISTE U ZAGREBU FAKULTET ELEKTROTEHNIKE I RACUNARSTVA", "UNIVERSITAT DE GIRONA", "UNIVERSITY OF LIMERICK", "CONSORCIO PARA EL DISENO, CONSTRUCCION, EQUIPAMIENTO Y EXPLOTACION DE LA PLATAFORMA OCEANICA DE CANARIAS", "NATO SCIENCE AND TECHNOLOGY ORGANISATION", "HERIOT-WATT UNIVERSITY", "NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU", "MARINE INSTITUTE", "DISTRETTO LIGURE DELLE TECNOLOGIE MARINE SCRL", "NATURAL ENVIRONMENT RESEARCH COUNCIL", "INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER"], "EU_Contribution": ["EUR 4 998 736,75"], "Project_Title": ["Marine robotics research infrastructure network"], "Total_Cost": ["EUR 4 998 736,75"], "Country": ["Portugal", "Germany", "Portugal", "Italy", "Croatia", "Spain", "Ireland", "Spain", "Belgium", "United Kingdom", "Norway", "Ireland", "Italy", "United Kingdom", "France"], "Project_ACR": ["EUMarineRobots"], "Technology_Description": "Our oceans are the least-explored region of planet Earth. Protection and sustainable development of ocean resources presents formidable challenges. Robots will play an increasingly key role in the near future and this role will expand and become more challenging as we extend into deeper, remote and hostile marine environments. Europe leads in many aspects of maritime, but lacks well integrated and coordinated oceanic robotic infrastructure or presence.", "To": ["2021-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["INFRAIA-02-2017 - Integrating Activities for Starting Communities"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Portugal"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations"], "From": ["2018-03-01"], "Project_ID": ["731103"], "Call_for_Proposal": ["H2020-INFRAIA-2017-1-two-stage"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSITE DE LIEGE", "MIKROBIOLOGICKY USTAV - AVCR, V.V.I.", "UNIVERSITAET ROSTOCK", "ITA-SUOMEN YLIOPISTO", "UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA", "FCIENCIAS.ID - ASSOCIACAO PARA A INVESTIGACAO E DESENVOLVIMENTO DE CIENCIAS", "SKOLKOVO INSTITUTE OF SCIENCE AND TECHNOLOGY", "THE UNIVERSITY OF WARWICK", "BRUKER DALTONIK GMBH", "CASC4DE", "ABSISKEY"], "EU_Contribution": ["EUR 4 988 746,50"], "Project_Title": ["European Network of Fourier-Transform Ion-Cyclotron-Resonance Mass Spectrometry Centers"], "Total_Cost": ["EUR 5 032 451,97"], "Country": ["France", "Belgium", "Czech Republic", "Germany", "Finland", "Italy", "Portugal", "Russia", "United Kingdom", "Germany", "France", "France"], "Project_ACR": ["EU_FT-ICR_MS"], "Technology_Description": "EU_FT-ICR_MS proposal aims to establish a European network of FT-ICR (Fourier Transform Ion Cyclotron Resonance) mass spectrometry (MS) centers in association with a manufacturer and a SME software company. Mass spectrometry (MS) has become the most ubiquitous analytical techniques in use today, providing more information on the composition and the structure of a substance from a smaller amount of sample than any other techniques. Unlike other analytical techniques, such as NMR, which mainly rely on a unique technology, MS is characterized by the existence of a large range of mass analyzers. FT-ICR MS is the most powerful MS technique. It offers up to 100 fold higher mass resolving power and mass accuracy than any other MS technique. On the contrary to NMR community with which the FT-ICR MS shares several features, FT-ICR MS has never been involved in a European INFRA network and so will be a legitimate candidate to the Integrating Activities for Starting Communities call.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["INFRAIA-02-2017 - Integrating Activities for Starting Communities"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Other", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-01-01"], "Project_ID": ["731077"], "Call_for_Proposal": ["H2020-INFRAIA-2017-1-two-stage"]}, -{"Partners": ["INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE", "INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE TOULOUSE INSAT", "VLAAMSE INSTELLING VOOR TECHNOLOGISCH ONDERZOEK N.V.", "UNIVERSITE DE NANTES", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.", "Teknologian tutkimuskeskus VTT Oy", "UNIVERSITAT AUTONOMA DE BARCELONA", "CONSIGLIO NAZIONALE DELLE RICERCHE", "NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "THE UNIVERSITY OF MANCHESTER", "KNIME.GMBH", "WAGENINGEN UNIVERSITY", "LIFEGLIMMER GMBH", "INRA TRANSFERT S.A."], "EU_Contribution": ["EUR 5 000 000"], "Project_Title": ["Industrial Biotechnology Innovation and Synthetic Biology Accelerator"], "Total_Cost": ["EUR 5 000 157,97"], "Country": ["France", "France", "Belgium", "France", "Germany", "Finland", "Spain", "Italy", "Greece", "France", "Spain", "United Kingdom", "Germany", "Netherlands", "Germany", "France"], "Project_ACR": ["IBISBA 1.0"], "Technology_Description": "The overarching aim of IBISBA 1.0 is to support and accelerate the uptake of industrial biotechnology as a key enabling technology for advanced manufacturing. To do this, IBISBA 1.0 will provide a distributed network of research infrastructure facilities to promote R&D in bioprocess development and support this bioeconomy KET. The facilities cover a variety of experimental and in silico operations and disciplines, and together represent the R&D continuum in the range TRL2 to 6 needed to build quality biomanufacturing processes for industrialization. In addition to hardware, IBISBA 1.0 will operate an ICT platform, linking all project events occurring on facilities, and external data repositories, and provide users with end-to-end project management and access to a wide variety of research assets. Together, these developments create the basis for a future pan-European research infrastructure for industrial biotechnology, the feasibility of which will be established during the project. Through IBISBA 1.0, the participant facilities will be opened for transnational access, thus providing cutting edge technologies to a cross section of Europe\u2019s researchers, including early career stage scientists. Users and facility operators will receive remote and on-site training, and immersion in the hallmark multidisciplinary environment of IBISBA 1.0. Transnational access will be facilitated by an ambition outreach plan that will provide users, including SMEs and other industry players, with complete information about service offers, but also insight into the potentiality of IPR held by IBISBA 1.0 partners and the opportunities for innovation. Interoperability will be a focus of considerable attention, with actions directed towards harmonization and the implementation of repeatable working practices that integrate experimentation with data analysis, and data management, thus providing the basis for the sharing and reuse of data assets in a framework of Open Science.", "To": ["2021-11-30, ongoing project"], "Meta": [""], "Topic_s": ["INFRAIA-02-2017 - Integrating Activities for Starting Communities"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-12-01"], "Project_ID": ["730976"], "Call_for_Proposal": ["H2020-INFRAIA-2017-1-two-stage"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM", "DOUGLAS CONNECT GMBH", "NATURAL ENVIRONMENT RESEARCH COUNCIL", "NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA", "UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN", "ACONDICIONAMIENTO TARRASENSE ASSOCIACION", "BUNDESINSTITUT FUER RISIKOBEWERTUNG", "BIONANONET FORSCHUNGSGESELLSCHAFT MBH", "PARIS-LODRON-UNIVERSITAT SALZBURG", "NOVAMECHANICS LIMITED", "BIOMAX INFORMATICS AG", "UNIVERSITEIT MAASTRICHT", "DUKE UNIVERSITY"], "EU_Contribution": ["EUR 5 400 000"], "Project_Title": ["The European Nanotechnology Community Informatics Platform: Bridging data and disciplinary gaps for industry and regulators (NanoCommons)"], "Total_Cost": ["EUR 5 586 000,46"], "Country": ["United Kingdom", "Switzerland", "United Kingdom", "Greece", "Ireland", "Spain", "Germany", "Austria", "Austria", "Cyprus", "Germany", "Netherlands", "United States"], "Project_ACR": ["NanoCommons"], "Technology_Description": "Nanotechnologies and the resulting novel and emerging materials (NEMs) represent major areas of investment and growth for the European economy. Recent advances have enabled confidence in the understanding of what constitutes toxicity of NEMs in relation to health and environmental hazards. However, the nanotechnology and nanosafety communities remain disparate and unconnected, whilst knowledge and data remain fragmented and inaccessible, such that from a data integrating and mining perspective it is clearly a \u201cstarting community\u201d. The field, and indeed the European open knowledge economy, requires conversion of these scientific discoveries into legislative frameworks and industrial applications, which can only be achieved through concerted efforts to integrate, consolidate, annotate and facilitate access to the disparate datasets. NanoCommons brings together academia, industry and regulators to facilitate pooling and harmonising of methods and data for modelling, safe-by-design product development and regulatory approval purposes, thereby driving best practice and ensuring maximum access to data and tools. Networking Activities span community needs assessment through development of demonstration case studies (e.g. exemplar regulatory dossiers). Joint Research Activities will integrate existing resources and organise efficient curation, preservation and facilitate access to data/models. Transnational Access will focus on standardisation of data generation workflows across the disparate communities and establishment of a common access procedure for transnational and/or virtual access to the data, and modelling and risk prediction/management tools developed and integrated. Given the extremely rapid pace of development of nanoinformatics, NanoCommons\u2019s detailed workplan will be prescribed for the first 18 months, beyond which it will be co-developed with stakeholders on a rolling call basis to ensure maximum responsiveness to community needs.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["INFRAIA-02-2017 - Integrating Activities for Starting Communities"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["731032"], "Call_for_Proposal": ["H2020-INFRAIA-2017-1-two-stage"]}, -{"Partners": ["UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.", "STICHTING IMEC NEDERLAND", "KARLSRUHER INSTITUT FUER TECHNOLOGIE", "POLITECNICO DI TORINO", "ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA", "UNIVERSITA DEGLI STUDI DI PERUGIA", "UNIVERSITY OF SOUTHAMPTON"], "EU_Contribution": ["EUR 5 213 481,25"], "Project_Title": ["European Infrastructure Powering the Internet of Things"], "Total_Cost": ["EUR 5 214 731,25"], "Country": ["Ireland", "France", "Germany", "Netherlands", "Germany", "Italy", "Italy", "Italy", "United Kingdom"], "Project_ACR": ["EnABLES"], "Technology_Description": "EnABLES will integrate key European research infrastructures in powering the Internet of Things (IoT). 6 research institutes together with 5 knowledge hubs of excellence will address the long term needs of energy management in self-powered smart sensor systems as required by IoT innovation. To enable truly \u2018invisible\u2019, unobtrusive and self-powered (autonomous) wireless devices a key challenge is to bridge the gap between capturing energy supply from energy harvesting sources (EH), integrating new devices for energy storage (ES) and taking into account the micro-power management (MPM) requirements for the miniaturised system operation. Through providing access to unique infrastructure, world-leading expertise, advanced equipment and state-of-the-art technologies, EnABLES will empower several hundreds of academic researchers and technologists to advance energy harvesting, storage and micropower management solutions for the integrated design and deployment of miniaturised autonomous sensors. Access will range from materials & models to devices and systems and the access providers will work with the user community to accelerate adoption and innovation in real-life applications. The EnABLES integration offers a paradigm shift in building an infrastructure network that links new scientific knowledge with application-driven research. Specifically for energy management solutions, this will deliver a mind-set change for early concurrent and collaborative development of system-optimised IoT devices. This presents a unique opportunity for Europe to uphold global leadership in microsystem energy management and be positioned at a pivotal time at the heart of the IoT innovation.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["INFRAIA-02-2017 - Integrating Activities for Starting Communities"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["730957"], "Call_for_Proposal": ["H2020-INFRAIA-2017-1-two-stage"]}, -{"Partners": ["WAGENINGEN UNIVERSITY", "WAGENINGEN UNIVERSITY"], "EU_Contribution": ["EUR 1 999 843"], "Project_Title": ["Surviving salinity: How do plants sense Na+?"], "Total_Cost": ["EUR 1 999 843"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["Sense2SurviveSalt"], "Technology_Description": "A major gap in our knowledge of how plants respond to soil salinity is their initial perception of sodium (Na+) ions. Salt is detrimental to plants and soil salinization is an increasing threat to global food security; 6% of the world\u2019s total land area and 20% of irrigated land is affected by salinity. I recently discovered Na+-specific root growth responses of plants and will now exploit these to identify the elusive sodium sensing mechanism of plants. I will use an innovative approach combining genome-wide genetic screens in the model plant Arabidopsis thaliana with dedicated biochemical assays. ", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["724321"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE", "SRUC", "WAGENINGEN UNIVERSITY", "STICHTING WAGENINGEN RESEARCH", "THE UNIVERSITY OF READING", "LEIBNIZ-INSTITUT FUR NUTZTIERBIOLOGIE", "TEAGASC - AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY", "AARHUS UNIVERSITET", "INSTITUT DE RECERCA I TECNOLOGIA AGROALIMENTARIES", "CENTRE WALLON DE RECHERCHES AGRONOMIQUES", "INSTITUT DE L'ELEVAGE", "FEDERAZIONE EUROPEA DI ZOOTECNICA", "AGRIMETRICS LIMITED", "INRA TRANSFERT S.A."], "EU_Contribution": ["EUR 4 999 943,75"], "Project_Title": ["SmartCow: an integrated infrastructure for increased research capability and innovation in the European cattle sector"], "Total_Cost": ["EUR 4 999 943,75"], "Country": ["France", "United Kingdom", "Netherlands", "Netherlands", "United Kingdom", "Germany", "Ireland", "Denmark", "Spain", "Belgium", "France", "Italy", "United Kingdom", "France"], "Project_ACR": ["SmartCow"], "Technology_Description": "SmartCow integrates key European cattle research infrastructures, to promote their coordinated use and development and thereby help the European cattle sector face the challenge of sustainable production. Covering all the relevant scientific fields and the diversity of cattle types and production systems, SmartCow will provide the academic and private research communities with easy access to 11 major research infrastructures from 7 countries (18 installations) of high quality services and resources. These are needed to develop innovative and ethical solutions for efficient use of animal and feed resources that promote animal welfare and healthy livestock, as well as sustainable competitiveness.", "To": ["2022-01-31, ongoing project"], "Meta": [""], "Topic_s": ["INFRAIA-02-2017 - Integrating Activities for Starting Communities"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Other", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-02-01"], "Project_ID": ["730924"], "Call_for_Proposal": ["H2020-INFRAIA-2017-1-two-stage"]}, -{"Partners": ["ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA", "UNIVERSIDAD AUTONOMA DE MADRID", "UNIVERSIDAD DE GRANADA", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSITE PARIS-SUD", "Marposs SpA", "GMV AEROSPACE AND DEFENCE SA", "TRUSTEES OF PRINCETON UNIVERSITY", "THE REGENTS OF THE UNIVERSITY OF CALIFORNIA", "MASSACHUSETTS INSTITUTE OF TECHNOLOGY", "YALE UNIVERSITY", "JOHNS HOPKINS UNIVERSITY", "UNIVERSITY OF PITTSBURGH", "UNIVERSITY OF HOUSTON SYSTEM", "THE UNIVERSITY OF TEXAS SYSTEM", "THE WASHINGTON UNIVERSITY CORPORATION", "WORCESTER POLYTECHNIC INSTITUTE", "UNIVERSIDAD DE BUENOS AIRES", "ACADEMIA SINICA"], "EU_Contribution": ["EUR 1 782 000"], "Project_Title": ["Geometric and Harmonic Analysis with Interdisciplinary Applications"], "Total_Cost": ["EUR 1 930 500"], "Country": ["Italy", "Spain", "Spain", "France", "France", "Italy", "Spain", "United States", "United States", "United States", "United States", "United States", "United States", "United States", "United States", "United States", "United States", "Argentina", "Taiwan"], "Project_ACR": ["GHAIA"], "Technology_Description": "GHAIA will promote excellence through mobility to the world leader Universities in pure and applied mathematical research: Princeton University, Mit, Yale, Johns Hopkins, the Universities of California, of Texas, of Houston, of Pittsburgh, the Washington University (St. Louis), and the Worchester Polytechnical Institute, the Academia Sinica, the University of Buenos Aires have joined the consortium. European researchers will have the extraordinary opportunity to work in their exciting environment as well as receiving visiting researchers from south America. Moreover two selected enterprises have joined the consortium, allowing intersectorial mobility: Marposs and GMV, leaders in the strategic sectors of EU industry of precision equipments for automatic inspection, and of satellite navigation.", "To": ["2021-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["777822"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["CONSIGLIO NAZIONALE DELLE RICERCHE", "UNIVERSITA CA' FOSCARI VENEZIA", "UNIVERSITY OF PIRAEUS RESEARCH CENTER", "UNIVERSITE DE VERSAILLES SAINT-QUENTIN-EN-YVELINES.", "HAROKOPIO UNIVERSITY", "DIMOS THIRAS", "UNIVERSIDADE FEDERAL DE SANTA CATARINA.", "UNIVERSIDADE FEDERAL DO CEARA", "FACULDADES CATOLICAS ASSOCIACAO SEM FINS LUCRATIVOS", "DALHOUSIE UNIVERSITY"], "EU_Contribution": ["EUR 504 000"], "Project_Title": ["Multiple ASpects TrajEctoRy management and analysis"], "Total_Cost": ["EUR 576 000"], "Country": ["Italy", "Italy", "Greece", "France", "Greece", "Greece", "Brazil", "Brazil", "Brazil", "Canada"], "Project_ACR": ["MASTER"], "Technology_Description": "An ever-increasing number of diverse, real-life applications, ranging from mobile phone calls to social media and land, sea, and air surveillance systems, produce massive amounts of spatio-temporal data representing trajectories of moving objects. Trajectories, commonly represented by sequences of timestamps and position coordinates, thanks to the high availability of contextual and semantic-rich data can be enriched and are evolving to more comprehensive and semantically significant objects. In the MASTER project we envision holistic trajectories, meaning trajectories characterized by the fact that the spatio-temporal and semantic aspects are intimately correlated and should be considered as a whole. However current state of art does not provide management and analysis methods \u201cready for use\u201d for these multiple aspects trajectories. ", "To": ["2022-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["777695"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Deciphering Regulatory DNA and Transcription Factor Binding Sites in C3 and C4 Species with Varying Water Use Efficiencies"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["Trans C4"], "Technology_Description": "Water-related stress is the number one limiting factor for plant productivity and human well-being. One-third of the current world population faces water shortages and by 2025, two-thirds are expected to experience water stress conditions, i.e 1.8 billion people will be subjected to absolute water scarcity.", "To": ["2020-06-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-07-01"], "Project_ID": ["735105"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF NOTTINGHAM", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "KUNGLIGA TEKNISKA HOEGSKOLAN", "OFFICE NATIONAL D'ETUDES ET DE RECHERCHES AEROSPATIALES", "R.TECH", "Zhejiang University", "BEIHANG UNIVERSITY", "XI'AN JIAOTONG UNIVERSITY", "JOHNS HOPKINS UNIVERSITY"], "EU_Contribution": ["EUR 504 000"], "Project_Title": ["Control of turbulent friction force"], "Total_Cost": ["EUR 706 500"], "Country": ["United Kingdom", "United Kingdom", "Sweden", "France", "France", "China", "China", "China", "United States"], "Project_ACR": ["CTFF"], "Technology_Description": "CTFF is a major interdisciplinary project that combines wisdoms in three academic disciplines: Heat Transfer, Fluid Physics and Plasma Physics, to address the research problem on both active and passive control of turbulent friction force. The main focus is on developing techniques for the control of near-wall turbulent structures and the reduction of turbulent friction force, specifically at conditions relevant to engineering practices, by coordinating the efforts of European, the US and Chinese experts specialized in these three different but overlapping domains. New materials will be examined, novel numerical algorithms will be developed, and the numerical results will be tested in physical experiments. In brief, the main objective of this project is to coordinate the action of a group of Universities and enterprises, with complementary expertise in three disciplines from European countries, China and the US, to build and test an optimal solution for the reduction of turbulent friction drag, thereby facilitating the successful implementation of friction force control in engineering practices.", "To": ["2020-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["777717"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["Institute of Science and Technology Austria", "Institute of Science and Technology Austria"], "EU_Contribution": ["EUR 1 996 030"], "Project_Title": ["Principles of Neural Stem Cell Lineage Progression in Cerebral Cortex Development"], "Total_Cost": ["EUR 1 996 030"], "Country": ["Austria", "Austria"], "Project_ACR": ["LinPro"], "Technology_Description": "The cerebral cortex consists of an extraordinary number and great diversity of neurons. Yet, how the cortical entity, with all its functional neuronal circuits, arises from the neural stem cells (NSCs) in the developing neuroepithelium is a major unsolved question in Neuroscience. Radial glia progenitors (RGPs) are responsible for producing nearly all neocortical neurons and a certain fraction of cortical glia including astrocytes. Our recent efforts provide evidence for a high degree of non-stochasticity and thus deterministic nature of RGP behavior in the mammalian neocortex. However, the cellular and molecular mechanisms controlling RGP lineage progression through proliferation, neurogenesis and especially gliogenesis are unknown. In a pursuit to obtain definitive insights into these fundamental questions we assess RGP lineage progression at the unprecedented single cell resolution, using the unique genetic MADM (Mosaic Analysis with Double Markers) technology. MADM offers an unparalleled approach to visualize and concomitantly manipulate sparse clones and small subsets of genetically defined neurons. Within the scope of this project we will use multidisciplinary experimental approaches to establish a research program with the following major objectives: We will 1) Functionally dissect the relative contribution of cell-autonomous intrinsic signaling and cell-non-autonomous effects in RGP lineage progression; 2) Define the principles of lineage progression in human RGPs in situ using MADM technology in cerebral organoid system; 3) Decipher the logic of glia lineage progression in the neocortex. The ultimate goal of the proposed research is to establish a definitive quantitative framework and mechanistic model of lineage progression in cortical NSCs. As such, the proposed research shall precipitate into extensive conceptual progress regarding the fundamental cellular and molecular principles of cerebral cortex development.", "To": ["2022-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["725780"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM", "INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM"], "EU_Contribution": ["EUR 149 379"], "Project_Title": ["Microfluidic bubble JET flow CELL sorter for cell therapy"], "Total_Cost": ["EUR 149 379"], "Country": ["Belgium", "Belgium"], "Project_ACR": ["JetCell"], "Technology_Description": "'T cell based cancer therapy has been recognized as one of the most promising future cancer therapy methods. In a typical T cell therapy course, relevant T cells are isolated from the patient\u2019s blood, modified against certain cancer markers, and infused back into the patient\u2019s body where the engineered T cells direct the immune system to attack and finally eliminate the malignant tumor cells and tissues. ", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Belgium"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["727730"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI PAVIA", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "INSTITUT GUSTAVE ROUSSY", "INTEGRATED SYSTEMS ENGINEERING SRL", "CELLINK AB", "KNOWLEDGE INNOVATION MARKET S.L."], "EU_Contribution": ["EUR 2 998 500"], "Project_Title": ["Genetically engineered human pluripotent stem cells, functionalized silk-fibroin platforms and bio-inks: a novel solution for large-scale ex-vivo platelet production, transfusion and drug research"], "Total_Cost": ["EUR 2 998 500,01"], "Country": ["Italy", "United Kingdom", "France", "Italy", "Sweden", "Spain"], "Project_ACR": ["SilkFUSION"], "Technology_Description": "The demand for human platelets (plts) for medical research and clinical applications is massive. The primary goal of SilkFUSION is to engineer groundbreaking 3D nanotechnologies for large-scale production of blood plts for human transfusion from human pluripotent stem cells (hPSCs). Our hypothesis is that plt production ex-vivo can be optimized by providing megakaryocytes (Mks) with the correct physical and biochemical environment.", "To": ["2021-10-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-01-2016-2017 - FET-Open research and innovation actions"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-11-01"], "Project_ID": ["767309"], "Call_for_Proposal": ["H2020-FETOPEN-1-2016-2017"]}, -{"Partners": ["CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL", "CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Microchannels for controlling cellular mechanotransduction"], "Total_Cost": ["EUR 150 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["CHANNELMAT"], "Technology_Description": "Cells respond to external mechanical stimuli through an activation of a cellular mechanism called mechanotransduction. The cellular responses in this mechanism are expressed by a modification in cellular proliferation, migration and differentiation, as well as in a strengthening of their adhesion. Likewise, diseases such as cancer and cardiac dysfunctions are also related to cellular mechanotransduction. Here we propose to take a novel 3D material porous material towards commercial applications. The material serves as a platform for controlling mechanotransduction (e.g. in implant materials) and enables a control of mechanotransduction by mimicking natural 3D cellular environments. Our material contains a novel form of microporous structures represented by micron-sized channels embedded in a polymer matrix of a well-defined stiffness that has been developed within the ERC project CELLINSPIRED. The material guarantees pore interconnectivity independently of pore density and size, a unique feature offered by our fabrication procedure, for which we have applied for a patent (EP 15166793.8, PCT/EP2016/060160). Furthermore, it also provides a large, three-dimensionally controlled cell-surface contact area, such that the mechanical properties of the environment will have large impact on the cells. Our goal in this project is to validate our novel material for cellular applications where mechanotransduction is targeted. The expected outcome of our project is to receive a demonstrator material that (1) has well-defined mechanical properties, porosities and pore dimensions, (2) is biocompatible and can be sterilized, (3) can be fabricated in different levels of complexity, (4) can activate mechanotransduction in cells, and (5) can be fabricated using high-throughput processes. As for commercialization, we aim to license the patent to biomaterials companies involved in applications that range from 3D cell cultures to implant materials.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["768740"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["BIOSENSE INSTITUTE - RESEARCH AND DEVELOPMENT INSTITUTE FOR INFORMATION TECHNOLOGIES IN BIOSYSTEMS", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "THE UNIVERSITY OF BIRMINGHAM", "INOSENS DOO NOVI SAD", "PLASMORE SRL", "THE UNIVERSITY OF TEXAS SYSTEM", "THE AUSTRALIAN NATIONAL UNIVERSITY", "RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK"], "EU_Contribution": ["EUR 553 500"], "Project_Title": ["Non-Conventional Wave Propagation for Future Sensing and Actuating Technologies"], "Total_Cost": ["EUR 580 500"], "Country": ["Serbia", "Switzerland", "United Kingdom", "Serbia", "Italy", "United States", "Australia", "United States"], "Project_ACR": ["NOCTURNO"], "Technology_Description": "New sensing devices and technologies are the key in addressing numerous challenges that agriculture is facing today. Namely, to provide more food for the ever-growing population, a number of biophysical parameters of plants, soil and food products need to be monitored and measured constantly, thus providing valuable data needed to optimize the entire agricultural process. In addition, the corresponding actuating technologies responsible for applying various measures (e.g. irrigation, fertilization) need to become more precise and allow variable rate inputs with a resolution down to an individual plant.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Serbia"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other"], "From": ["2018-01-01"], "Project_ID": ["777714"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["FUNDACAO D. ANNA SOMMER CHAMPALIMAUD E DR. CARLOS MONTEZ CHAMPALIMAUD", "FUNDACAO D. ANNA SOMMER CHAMPALIMAUD E DR. CARLOS MONTEZ CHAMPALIMAUD"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Circuit mechanisms of self-movement estimation during walking"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Portugal", "Portugal"], "Project_ACR": ["activeFly"], "Technology_Description": "The brain evolves, develops, and operates in the context of animal movements. As a consequence, fundamental brain functions such as spatial perception and motor control critically depend on the precise knowledge of the ongoing body motion. An accurate internal estimate of self-movement is thought to emerge from sensorimotor integration; nonetheless, which circuits perform this internal estimation, and exactly how motor-sensory coordination is implemented within these circuits are basic questions that remain to be poorly understood. There is growing evidence suggesting that, during locomotion, motor-related and visual signals interact at early stages of visual processing. In mammals, however, it is not clear what the function of this interaction is. Recently, we have shown that a population of Drosophila optic-flow processing neurons \u2014neurons that are sensitive to self-generated visual flow, receives convergent visual and walking-related signals to form a faithful representation of the fly\u2019s walking movements. Leveraging from these results, and combining quantitative analysis of behavior with physiology, optogenetics, and modelling, we propose to investigate circuit mechanisms of self-movement estimation during walking. We will:1) use cell specific manipulations to identify what cells are necessary to generate the motor-related activity in the population of visual neurons, 2) record from the identified neurons and correlate their activity with specific locomotor parameters, and 3) perturb the activity of different cell-types within the identified circuits to test their role in the dynamics of the visual neurons, and on the fly\u2019s walking behavior. These experiments will establish unprecedented causal relationships among neural activity, the formation of an internal representation, and locomotor control. The identified sensorimotor principles will establish a framework that can be tested in other scenarios or animal systems with implications both in health and disease.", "To": ["2022-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Portugal"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-11-01"], "Project_ID": ["759782"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Carrier for Cure: tailored combination drug delivery solutions for oncology"], "Total_Cost": ["EUR 150 000"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["CfC"], "Technology_Description": "Chemotherapy, often given in conjunction with other therapies is infamous for its off target associated side effects. Recent studies have shown that drugs combinations can act synergistically at certain ratios and are more effective and less toxic than single drug therapies. Despite promising in vitro results, combination drug therapy for Oncology has not been successfully translated to the clinic due to lack of efficient delivery systems that can maintain the desired synergistic drug concentrations in the body as each drug has a different pharmacokinetics and toxicity profile. The objective of this project is to develop a universal platform for simultaneous delivery of multiple drugs to specific cells in vivo using a protein cage that was developed in our laboratory for encapsulation of diverse cargoes.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["768667"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Principles of Musical Structure Building: Theory, Computation, and Cognition"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["PMSB"], "Technology_Description": "Music is a central human trait across all cultures and historical periods, involving a great rich variety of parameters, cognitive processes, and forms of structure building. The proposed project aims at advancing the understanding of human cognition and, specifically, the capacity to represent and process complex auditory sequences and syntactic structures by exploring the rich potential of music perception.", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["760081"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF EV", "HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF EV"], "EU_Contribution": ["EUR 1 499 625"], "Project_Title": ["Towards the Bottom of the Periodic Table"], "Total_Cost": ["EUR 1 499 625"], "Country": ["Germany", "Germany"], "Project_ACR": ["TOP"], "Technology_Description": "Actinide and lanthanide chemistry is currently experiencing a renaissance, due to the prospects of obtaining novel materials relevant for applications in chemical synthesis, electronics, materials science, nanotechnology, biology and medicine. Most of the fascinating properties of the lanthanide and actinide materials are related to the partially filled 4f/5f valence shell and in contrast to the rest of the periodic table, are poorly understood. This includes the surprising reactivity, magnetic and crystal structure properties and, the rather unpredictable, covalent or ionic nature of their bonds. It is now possible to study the chemistry of the f-block elements using state-of-the-art techniques that were not available before. Two new synchrotron-based techniques, high energy resolution fluorescence detection (HERFD) X-ray absorption spectroscopy and resonant inelastic X-ray scattering (RIXS), can now provide unprecedented detailed information on processes such as the electron-electron interactions, hybridization between molecular orbitals, the nature of their chemical bonding, and the occupation and the degree of the f-electron localization. Therefore, I propose to apply these cutting-edge techniques to advance the fundamental understanding of the lanthanide and actinide nanoparticles, an outstanding problem in materials science, chemistry and environmental science technology. The research will be conducted at the European Synchrotron (ESRF), at the Rossendorf Beamline (ROBL) dedicated to actinide science, where we recently installed a novel X-ray emission spectrometer with ground-breaking detection limits. The experimental work will be complemented by electronic structure calculations. The combined experimental and theoretical data will provide an essential knowledge of lanthanide and actinide chemistry, significant for topics of high societal relevance, like green chemistry, renewable energy and catalysis.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["759696"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY", "TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Neuronal regulation of immunity"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Israel", "Israel"], "Project_ACR": ["NEIMO"], "Technology_Description": "The philosophical \u2018mind-body problem\u2019 examines the relationship between the mind, a mental process, and its impact on the body, a physical entity. It has multiple manifestations in modern medicine, for example, the emergence of disease following stress, or recovery in response to placebo treatment. Nevertheless, this fundamental aspect of physiology remains largely unexplored. Here we propose to approach this question by focusing on a specific aspect of brain-body interactions. Namely, to study how the brain's interoceptive site, the insular cortex, affects the immune system, the body\u2019s main protective mechanism. We will explore the interactions between the insula and the immune system on two levels. First, we will focus on the insula and its projections within the brain; secondly, we will study the role of projections from the brain, specifically, the peripheral nervous system (PNS), which innervates all the immunological organs. We will use chemogenetics to activate/inhibit the activity of neurons in the insula, and optogenetics to locally control, using light, the activity of sympathetic and parasympathetic neurons innervating immunological sites. We will then characterize the effects of these neuronal manipulations on the immune system to decipher fundamental principles of the dialog between nerve and immune cells with the long term goal of harnessing the brain\u2019s therapeutic potential. My multidisciplinary background places me in a unique position to investigate brain regulation of immunity, and our preliminary data support our central hypothesis that the brain and, specifically, the insula, regulate immune responses. Taken together, this study promises to alter our understanding of brain-body interactions, and to set the stage for novel approaches to analyze how the state of the mind impacts physiology.", "To": ["2022-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["758952"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 242 400"], "Project_Title": ["Elliptic Combinatorics: Solving famous models from combinatorics, probability and statistical mechanics, via a transversal approach of special functions"], "Total_Cost": ["EUR 1 242 400"], "Country": ["France", "France"], "Project_ACR": ["COMBINEPIC"], "Technology_Description": "I am willing to solve several well-known models from combinatorics, probability theory and statistical mechanics: the Ising model on isoradial graphs, dimer models, spanning forests, random walks in cones, occupation time problems. Although completely unrelated a priori, these models have the common feature of being presumed \u201cexactly solvable\u201d models, for which surprising and spectacular formulas should exist for quantities of interest. This is captured by the title \u201cElliptic Combinatorics\u201d, the wording elliptic referring to the use of special functions, in a broad sense: algebraic/differentially finite (or holonomic)/diagonals/(hyper)elliptic/ hypergeometric/etc.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-02-01"], "Project_ID": ["759702"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["OSPEDALE SAN RAFFAELE SRL", "OSPEDALE SAN RAFFAELE SRL"], "EU_Contribution": ["EUR 1 498 125"], "Project_Title": ["Dissecting Cross-Regulatory Interplays in Tumor-Associated Macrophages"], "Total_Cost": ["EUR 1 498 125"], "Country": ["Italy", "Italy"], "Project_ACR": ["X-TAM"], "Technology_Description": "Macrophages are specialized innate immune cells with central roles in homeostasis and disease. Upon", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Italy"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-03-01"], "Project_ID": ["759532"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 499 844"], "Project_Title": ["Into the Eastern Desert of Egypt from the New Kingdom to the Roman period"], "Total_Cost": ["EUR 1 499 844"], "Country": ["France", "France"], "Project_ACR": ["Desert Networks"], "Technology_Description": "The desert is a paradox: it is at the same time arid and rich in resources, a margin and an interface. Far from being a no man\u2019s land, it is a social space of linked solidarities. The \u201cDesert Networks\u201d project aims to explore the reticular organisation of such a zone by focusing on the southern part of the Eastern Desert of Egypt. Located between the Nile and the Red Sea, it has always been a tantalizing region for Egypt and beyond. Its ancient remains are admirably preserved and ancient sources about and from the region itself are numerous. Yet, the history of its occupation and appropriation remains a static and compartmentalized one. Therefore, the ambition of the project is to cross disciplinary borders and achieve an epistemological break by working for the first time in and on the Eastern desert as a dynamic object, both from a long-term perspective (mid-second millennium BC - late third century AD), and by analysing the patterns and functions of the different networks that linked its various nodes using the connectivity theory that reshaped scholarly paradigms for the Mediterranean in the 2000s. As the head of the French Eastern Desert mission, the PI will co-ordinate a multidisciplinary team. For the first time, the project will gather all the data unearthed in the region over 300 years, as well as the expected data from the excavations conducted by the project, in a database linked with a GIS. A collaborative and online open access map of the Eastern Desert will be created and will serve for the spatial analyses and rendering of the real, economic and social networks in the area. These networks evolved over time and through a shifting geography, as people experienced different perceptions of space. By assessing all these facets and confronting the archaeological material and written evidence, our final objective is to write a new history of the Eastern Desert from Pharaonic to Roman times, focusing on its networks and evaluating their meaning.", "To": ["2022-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-11-01"], "Project_ID": ["759078"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["STOCKHOLMS UNIVERSITET", "STOCKHOLMS UNIVERSITET"], "EU_Contribution": ["EUR 1 091 249,39"], "Project_Title": ["Topology of moduli spaces of Riemann surfaces"], "Total_Cost": ["EUR 1 091 249,39"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["MODULISPACES"], "Technology_Description": "The proposal describes two main projects. Both of them concern cohomology of moduli spaces of Riemann surfaces, but the aims are rather different.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["759082"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["KING'S COLLEGE LONDON", "KING'S COLLEGE LONDON"], "EU_Contribution": ["EUR 1 495 430"], "Project_Title": ["Engineering the Biointerface of Nanowires to Direct Stem Cell Differentiation"], "Total_Cost": ["EUR 1 495 430"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["EnBioN"], "Technology_Description": "ENBION will engineer a platform to direct the differentiation of stem cells by developing principles for the rational design of the biointerface of nanowires. ", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["759577"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["INSTITUT FUR MOLEKULARE BIOLOGIE GGMBH", "INSTITUT FUR MOLEKULARE BIOLOGIE GGMBH"], "EU_Contribution": ["EUR 1 497 750"], "Project_Title": ["Dissecting Quality Control Mechanisms of Mislocalized Proteins"], "Total_Cost": ["EUR 1 497 750"], "Country": ["Germany", "Germany"], "Project_ACR": ["MisloQC"], "Technology_Description": "Protein quality control systems maintain a functional proteome through detection and removal of abnormal proteins. While typically only misfolded or damaged molecules are thought of as abnormal, recent work has revealed that also mislocalized proteins are subject to quality control. Mislocalized proteins are defined as proteins that fail to reach their native compartment or fail to assemble into their native complex, and thus cannot function normally. Protein mislocalization is a constitutive problem caused by inefficiencies of cellular processes and increases with aging. Proteins can also mislocalize due to mutations, as seen in various metabolic, cardiovascular and neurodegenerative diseases, and some types of cancer.", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-03-01"], "Project_ID": ["759427"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["FUNDACIO INSTITUT DE RECERCA DE L'ENERGIA DE CATALUNYA", "STIFTELSEN SINTEF", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSIDAD AUTONOMA DE MADRID", "Institute of Applied Physics of the Academy of Sciences of Moldova", "HELMHOLTZ-ZENTRUM BERLIN FUR MATERIALIEN UND ENERGIE GMBH", "SOCIETATEA CU RASPUNDERE LIMITATA SUNGA", "UAB MODERNIOS E-TECHNOLOGIJOS", "MOROCCAN FOUNDATION FOR ADVANCED SCIENCE INNOVATION AND RESEARCHFONDATION MASCIR", "BELARUSSKY GOSUDARSTVENNIY UNIVERSITET INFORMATIKI I RADIOELEKTRONIKI", "UNIVERSITE MOHAMMED V DE RABAT", "UNIVERSITY OF THE WESTERN CAPE"], "EU_Contribution": ["EUR 1 318 500"], "Project_Title": ["International cooperation for the development of cost-efficient kesterite/c-Si thin film next generation tandem solar cells"], "Total_Cost": ["EUR 1 318 500"], "Country": ["Spain", "Norway", "France", "Spain", "Moldova", "Germany", "Moldova", "Lithuania", "Morocco", "Belarus", "Morocco", "South Africa"], "Project_ACR": ["INFINITE-CELL"], "Technology_Description": "Photovoltaic (PV) is recognized as one of the main renewable energy solutions for fulfilling the targets defined by the EU Energy Roadmap 2050 and the SET Plan. Most of the current commercial PV devices are formed by single junctions, and more complex device concepts allowing a significant increase in device efficiency (well beyond the theoretical limit in the 30%-33% range) are still mostly limited to expensive III-V technologies.", "To": ["2021-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["777968"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN", "KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN"], "EU_Contribution": ["EUR 1 499 403,74"], "Project_Title": ["The neuroenergetics of memory consolidation \u2013 hybrid PET/MR imaging of the default mode network"], "Total_Cost": ["EUR 1 499 403,74"], "Country": ["Germany", "Germany"], "Project_ACR": ["SUGARCODING"], "Technology_Description": "Since its discovery more than a decade ago, the most studied network in the human brain remains a paradox. The default mode network (DMN) is most active during the resting state and deactivates once subjects engage in goal directed behavior. Although reported in hundreds of studies using functional magnetic resonance imaging (fMRI), the function of the DMN is still unknown. I hypothesize that memories are consolidated in the DMN during resting state, a process that is interrupted once we engage in cognitive processing. This hypothesis is based on two complementary and recent findings. First, brain regions involved in encoding of novel or retrieval of consolidated memories strongly resemble regions of the DMN. Second, the DMN consumes most glucose during resting state as revealed by positron emission tomography (PET). Importantly, energy in the brain is mainly dedicated to neuronal signaling and synaptic plasticity related to memory consolidation.", "To": ["2023-06-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-07-01"], "Project_ID": ["759659"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["POLITECHNIKA SLASKA", "UNIVERSITY OF GLASGOW", "UNIVERSITY OF DURHAM", "HEINRICH-HEINE-UNIVERSITAET DUESSELDORF", "OSAKA UNIVERSITY", "NATIONAL TAIWAN UNIVERSITY", "UNIVERSIDADE FEDERAL DE SANTA CATARINA."], "EU_Contribution": ["EUR 832 500"], "Project_Title": ["Organic Charge Transfer Applications"], "Total_Cost": ["EUR 1 183 500"], "Country": ["Poland", "United Kingdom", "United Kingdom", "Germany", "Japan", "Taiwan", "Brazil"], "Project_ACR": ["OCTA"], "Technology_Description": "Organic molecules are everywhere, they are integral to life, from every living species to new technologies such as organic electronics. Organic molecules can be made with infinite variety and what happens when they are excited by light is just as varied and complex. Molecular shape and molecular interactions are important in their application but what happens to them once excited is just as critical and often defines the function of that molecular within a more complex system. One of very interesting phenomena in organic molecules is electron transfer (ET) to form stable Charge Transfer excited states (CT). We may observe CT states everywhere, from living tissue to organic solar cells or organic light emitting diodes. It is believed that birds use CT states to navigate. It is therefore crucial to understand the ET process and the CT state. CT states, bound electron and hole pairs, separated in space on different parts of a molecules or different molecules play an ever increasing role in organic optoelectronic devices be they OPV or OLED or in bioimaging.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Poland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["778158"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["UNIVERSITE CATHOLIQUE DE LOUVAIN", "UNIVERSITE CATHOLIQUE DE LOUVAIN"], "EU_Contribution": ["EUR 1 302 710"], "Project_Title": ["BIOMIMETIC FIXATION OF CO2 AS SOURCE OF SALTS AND GLUCOSE"], "Total_Cost": ["EUR 1 302 710"], "Country": ["Belgium", "Belgium"], "Project_ACR": ["CO2LIFE"], "Technology_Description": "The continued increase in the atmospheric concentration of CO2 due to anthropogenic emissions is leading to significant changes in climate, with the industry accounting for one-third of all the energy used globally and for almost 40% of worldwide CO2 emissions. Fast actions are required to decrease the concentration of this greenhouse gas in the atmosphere, value that has currently reaching 400 ppm. Among the technological possibilities that are on the table to reduce CO2 emissions, carbon capture and storage into geological deposits is one of the main strategies that is being applied. However, the final objective of this strategy is to remove CO2 without considering the enormous potential of this molecule as a source of carbon for the production of valuable compounds. Nature has developed an effective and equilibrated mechanism to concentrate CO2 and fixate the inorganic carbon into organic material (e.g., glucose) by means of enzymatic action. Mimicking Nature and take advantage of millions of years of evolution should be considered as a basic starting point in the development of smart and highly effective processes. In addition, the use of amino-acid salts for CO2 capture is envisaged as a potential approach to recover CO2 in the form of (bi)carbonates. ", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["759630"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA", "BCAM - BASQUE CENTER FOR APPLIED MATHEMATICS", "INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE", "BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION", "UNIVERSITAT POLITECNICA DE CATALUNYA", "REPSOL SA", "PONTIFICIA UNIVERSIDAD CATOLICA DE VALPARAISO", "CURTIN UNIVERSITY OF TECHNOLOGY", "THE UNIVERSITY OF TEXAS SYSTEM", "UNIVERSIDAD NACIONAL DE COLOMBIA", "PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE", "UNIVERSIDAD CENTRAL DE VENEZUELA", "UNIVERSIDAD DE BUENOS AIRES", "MACQUARIE UNIVERSITY"], "EU_Contribution": ["EUR 765 000"], "Project_Title": ["Multiscale Inversion of Porous Rock Physics using High-Performance Simulators: Bridging the Gap between Mathematics and Geophysics"], "Total_Cost": ["EUR 765 000"], "Country": ["Spain", "Spain", "France", "Spain", "Spain", "Spain", "Chile", "Australia", "United States", "Colombia", "Chile", "Venezuela", "Argentina", "Australia"], "Project_ACR": ["MATHROCKS"], "Technology_Description": "We will develop and exchange knowledge on applied mathematics, high-performance computing (HPC), and geophysics to better characterize the Earth\u00b4s subsurface. We aim to better understand porous rocks physics in the context of elasto-acoustic wave propagation phenomena. We will develop parallel high-continuity isogeometric analysis (IGA) simulators for geophysics. We will design and implement fast and robust parallel solvers for linear equations to model multi-physics electromagnetic and elasto-acoustic phenomena. We seek to develop a parallel joint inversion workflow for electromagnetic and seismic geophysical measurements. To verify and validate these tools and methods, we will apply the results to: characterise hydrocarbon reservoirs, determine optimal locations for geothermal energy production, analyze earthquake propagation, and jointly invert deep-azimuthal resistivity and elasto-acoustic borehole measurements. ", "To": ["2022-03-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-04-01"], "Project_ID": ["777778"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["THE UNIVERSITY OF EDINBURGH", "THE UNIVERSITY OF EDINBURGH"], "EU_Contribution": ["EUR 1 498 915"], "Project_Title": ["Stereoretentive-Enantioconvergent Catalysis: A New Concept in Asymmetric Synthesis"], "Total_Cost": ["EUR 1 498 915"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["SEC"], "Technology_Description": "This project will experimentally establish a new concept in asymmetric synthesis: stereoretentive-enantioconvergent catalysis. This will represent a completely new method for accessing enantiopure materials starting from racemic substrates and will therefore impact all areas of synthetic chemistry. The ability to synthesise chiral molecules in enantiopure form is vitally important, most recognisably for the pharmaceutical industry. This is because the molecules of life are chiral (e.g., D-sugars and L-amino acids) and enantiomers often interact very differently with living organisms. Classically, asymmetric synthesis utilising racemic substrates is limited to achieving a maximum yield of 50% (e.g., kinetic resolutions). Enantioconvergent catalysis avoids this limitation with both enantiomers of the starting material being converted into a single enantioenriched product, thanks to complex stereoablative or stereomutative de-racemisation processes. This project will establish a conceptually new stereoretentive-dimerisation approach that results in both enantiomers of the starting material being incorporated into the product with no de-racemisation required. This new concept will prove highly valuable for the synthesis of small enantiopure building blocks, which will be of high value in many areas of synthesis, and also for more complex late-stage transformations in complex molecule synthesis. Several approaches will be pursued to demonstrate proof-of-principle, and applications in the synthesis of complex natural and unnatural products will then be used to demonstrate the potential of stereoretentive-enantioconvergent catalysis in target-orientated synthesis.", "To": ["2022-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["759552"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN", "THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN"], "EU_Contribution": ["EUR 1 333 325"], "Project_Title": ["Open dynamics of interacting and disordered quantum systems"], "Total_Cost": ["EUR 1 333 325"], "Country": ["Ireland", "Ireland"], "Project_ACR": ["ODYSSEY"], "Technology_Description": "This research proposal focuses on the open quantum system dynamics of disordered and interacting many- body systems coupled to external baths. The dynamics of systems which contain both disorder and interactions are currently under intense theoretical investigation in condensed matter physics due to the discovery of a new phase of matter known as many-body localization. With the experimental realization of such systems in mind, this proposal addresses an essential issue which is to understand how coupling to external degrees of freedom influences dynamics. These systems are intrinsically complex and lie beyond the unitary closed system paradigm, so the research proposed here contains interdisciplinary methodology beyond the mainstream in condensed matter physics ranging from quantum information to quantum optics. The project has three principal objectives each of which would represent a major contribution to the field:", "To": ["2023-06-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-07-01"], "Project_ID": ["758403"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["TEL AVIV UNIVERSITY", "TEL AVIV UNIVERSITY"], "EU_Contribution": ["EUR 1 499 528"], "Project_Title": ["Supervised Verification of Infinite-State Systems"], "Total_Cost": ["EUR 1 499 528"], "Country": ["Israel", "Israel"], "Project_ACR": ["SVIS"], "Technology_Description": "Modern society relies more and more on computing for managing complex safety-critical tasks (e.g., in medicine, avionics, economy). Correctness of computerized systems is therefore crucial, as incorrect behaviors might lead to disastrous outcomes. Still, correctness is a big open problem without satisfactory theoretical or practical solutions. This has dramatic effects on the security of our lives. The current practice in industry mainly employs testing which detects bugs but cannot ensure their absence. In contrast, formal verification can provide formal correctness guarantees. Unfortunately, existing formal methods are still limited in their applicability to real world systems since most of them are either too automatic, hindered by the undecidability of verification, or too manual, relying on substantial human effort. This proposal will introduce a new methodology of supervised verification, based on which, we will develop novel approaches that can be used to formally verify certain realistic systems. This will be achieved by dividing the verification process into tasks that are well suited for automation, and tasks that are best done by a human supervisor, and finding a suitable mode of interaction between the human and the machine. Supervised verification represents a conceptual leap as it is centered around automatic procedures but complements them with human guidance; It therefore breaks the classical pattern of automated verification, and creates new opportunities, both practical and theoretical. In addition to opening the way for developing tractable verification algorithms, it can be used to prove lower and upper bounds on the asymptotic complexity of verification by explicitly distilling the human's role. The approaches developed by this research will significantly improve system correctness and agility. At the same time, they will reduce the cost of testing, increase developers productivity, and improve the overall understanding of computerized systems.", "To": ["2023-03-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-04-01"], "Project_ID": ["759102"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["THE UNIVERSITY OF EDINBURGH", "THE UNIVERSITY OF EDINBURGH"], "EU_Contribution": ["EUR 1 499 351"], "Project_Title": ["Energy transfer Processes at gas/wall Interfaces under extreme Conditions"], "Total_Cost": ["EUR 1 499 351"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["EPIC"], "Technology_Description": "In the future, high-efficiency (low CO2) vehicles will be powered in part by reinvented internal combustion (IC) engines that are \u201cdownsized\u201d and operate with new combustion modes. These engine concepts are subject to problems such as increased transient heat transfer and flame quenching in small passages. Near-wall transient heat transfer is not well-understood in engine environments; the gas is not constant in pressure, temperature, or velocity such that physical processes quickly digress from established theory. EPIC is uniquely placed to address these problems. A novel constant-volume chamber, offering realistic engine passages but with optical access, and which emulates the pressure/temperature time curve of a real engine, will be developed. This chamber will make it possible to measure the highly transient and highly variable processes at the gas/wall interface (including a highly dynamic flame front) for single- and two-wall passages. Measurements will be made using a suite of advanced laser diagnostics; a novel aspect of the proposed work as they have not been used in combination to study such a problem before. Hybrid fs/ps rotational coherent Raman (i.e. CARS) in a line format will provide transient gas temperature and species profiles normal to the wall surface in high-risk/high-gain packages. PIV/PTV measurements will further elucidate flow dynamics at the surface. Planar OH-LIF will help interpret CARS measurements and provide necessary details of flame transport and quenching. As the flame approaches the surface, phosphor thermometry will measure wall temperature and heat flux to elucidate the highly dynamic inter-coupling between flame and wall. EPIC will provide substantial breakthroughs in knowledge by measuring unsteady boundary layer development and understanding its influence on flame quenching for single- and two-wall surfaces. As such, EPIC will provide the fundamental knowledge that supports cleaner combustion technology for the future.", "To": ["2022-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["759546"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI MILANO", "UNIVERSITA DEGLI STUDI DI MILANO"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Eradicating Chronic Infections"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Italy", "Italy"], "Project_ACR": ["ERACHRON"], "Technology_Description": "Given the alarming progression of chronic and relapsing infections in the last decades, and the even more alarming predictions for the upcoming years, it is urgent for chemists to be able to provide new molecular tools to study, and ultimately solve, these complex biological problems. Bacterial persisters are an elusive \"dormant\" phenotype that play a pivotal role in chronic infections, with mechanisms that remain to be fully unravelled. Current knowledge suggests that bacterial persisters are not genetically resistant to antibiotic treatment; they simply appear to shut down through a cascade of biochemical events called the stringent response (SR), becoming insensitive to current drugs. This subpopulation remains unaffected during the time of pharmacological treatment and represents a reservoir that sustains pathogen survival and resurgence. The goal of this project is to fill the knowledge gap between persisters formation and infection eradication, providing the community with potent and selective small molecular tools that can be used to challenge complementary survival mechanisms.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["758108"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI PADOVA", "EOTVOS LORAND TUDOMANYEGYETEM", "VRIJE UNIVERSITEIT BRUSSEL", "UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN", "EUROPEAN MOLECULAR BIOLOGY LABORATORY", "UNIVERSIDAD NACIONAL DE QUILMES", "FUNDACION INSTITUTO LELOIR", "UNIVERSIDAD NACIONAL DE GENERAL SAN MARTIN"], "EU_Contribution": ["EUR 1 291 500"], "Project_Title": ["Driving the functional characterization of intrinsically disordered proteins"], "Total_Cost": ["EUR 1 291 500"], "Country": ["Italy", "Hungary", "Belgium", "Ireland", "Germany", "Argentina", "Argentina", "Argentina"], "Project_ACR": ["IDPfun"], "Technology_Description": "Intrinsically disordered proteins (IDPs), characterized by high conformational variability and interaction promiscuity, defy the classic protein structure-function paradigm. IDPs cover almost half of the residues in Eukaryotic proteomes. Growing evidence suggests that IDPs, interacting with multiple partners, are major players in cellular regulation and involved in numerous human diseases. Computational methods have contributed to the identification of IDPs from sequence and recently published curated IDP databases provide a starting point. However, functional knowledge for IDPs remains very limited.", "To": ["2022-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["778247"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["Institute of Science and Technology Austria", "Institute of Science and Technology Austria"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["A Fiber Optic Transceiver for Superconducting Qubits"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Austria", "Austria"], "Project_ACR": ["QUNNECT"], "Technology_Description": "Many researchers in basic science and large IT companies are convinced that superconducting quantum processors will soon help solve complex problems faster, improve optimization and simulation, and boost the progress in artificial intelligence. A worldwide quantum web is the next logical step. It would not only improve communication security, it represents the key to unlock the full potential of the new quantum-computing paradigm. ", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["758053"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIWERSYTET WROCLAWSKI", "SUBSIDIARY COMPANY PRINCETON BIOMOLECULAR RESEARCH LABS", "FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG", "SARA PHARM SOLUTIONS SRL", "UNIVERSITAT WIEN", "A.N. NESMEYANOV INSTITUTE OF ORGANOELEMENT COMPOUNDS OF RUSSIAN ACADEMY OF SCIENCES"], "EU_Contribution": ["EUR 796 500"], "Project_Title": ["Chiroptical, optical and magnetic probes for protein sensing based on cage metal complexes"], "Total_Cost": ["EUR 958 500"], "Country": ["Poland", "Ukraine", "Germany", "Romania", "Austria", "Russia"], "Project_ACR": ["CLATHROPROBES"], "Technology_Description": "The CLATHROPROBES project is devoted to the design and development of novel, highly efficient chiroptical, luminescent, IR, NMR and EPR probes for sensing and structural studies of biomolecules based on cage metal complexes (clathrochelates and lacunar complexes of spatial tris-diiminate ligands with encapsulated 3d-metal ion) as molecular reporters.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Poland"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["778245"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich"], "EU_Contribution": ["EUR 1 497 104"], "Project_Title": ["Enhancing brain function and cognition via artificial entrainment of neural oscillations"], "Total_Cost": ["EUR 1 497 104"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["ENTRAINER"], "Technology_Description": "Neural oscillations are ubiquitous in the human brain and have been implicated in diverse cognitive functions to support both neural communication and plasticity. Their functional relevance is further supported by a large number of studies linking various cognitive deficits (e.g., attention deficit hyperactivity disorder, ADHD) with abnormal neural oscillations. However, this field of research faces two important problems: First, there is only correlative, but no causal evidence linking cognitive deficits to abnormal neural oscillations in humans. Second, there is virtually no theory-driven mechanistic approach that generates insights into how oscillations within and across neural networks are linked to human behavior. In this project, I propose to take decisive steps to provide a long-needed neurophysiological characterization\u2014via (1) computational modelling, (2) electrophysiological measures, and (3) novel non-invasive manipulations of cortical rhythms\u2014on how neural oscillations contribute to two types of cognitive processes that are fundamental for many aspects of human behavior: attention and short-term memory. I will go a step further by demonstrating that it is possible to augment performance in these cognitive functions with the design of non-invasive brain stimulation protocols individually tailored to the theory-driven neurocomputational characterizations and electrophysiological signatures of each individual. This will result in the applied goal of deriving new neuro-computational assays that can detect deviant network interactions causally related to cognitive functions, which is key for then renormalizing those functions in neuropsychological conditions such as ADHD. Thus, if successful, my proposed work will ultimately result in novel, low-cost, and painless non-invasive neural interventions for a wide range of neuropsychological disorders tied to abnormal neural oscillations.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["758604"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITY OF BRISTOL", "UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 1 414 722"], "Project_Title": ["Legitimacy, Financialization, and Varieties of Capitalism: Understanding Sovereign Wealth Funds in Europe"], "Total_Cost": ["EUR 1 414 722"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["SWFsEUROPE"], "Technology_Description": "The number and size of sovereign wealth funds (SWF) has grown substantially in the last decade, leading to an unsettled debate regarding their legitimacy in the global political economy. Some suggest they represent the (re)emergence of state-led capitalism subject to geopolitical motivations that threaten free markets. For others, SWFs represent a source of long-term patient capital capable of mitigating market short-termism. Either way, SWFs challenge the norm, particularly in the West, that financial markets are spaces of exchange for non-state actors. In three complementary and interdisciplinary work programmes the SWFsEUROPE project will explain the evolving and variegated pattern of \u2018sovereign fund capitalism\u2019 in Europe, developing a new theory of the relationship between states and global finance. First, the project breaks new ground by explaining and theorizing how the legitimacy of SWFs as commercially oriented investors is performed when they are still entities of the state. No study has critically examined how legitimacy is performed via mechanisms such as the International Forum of Sovereign Wealth Funds and the Santiago Principles, or the growing evidence of collaboration with cognate institutional investors (e.g. pension funds). Second, this projects seeks a multi-layered explanation of the uneven pattern of investment flows and stocks of foreign SWFs into European countries through hypothesis testing of aggregate investment data with different theories of national-institutional variety, coupled with a comparative analysis of the bilateral investment-promotion relationships of investment-receiving countries. Third, the project will compare the growth and development of European SWFs. There is no comparative study exploring why some states are sponsors of an SWF (e.g. Italy, France, Ireland) and others are not (e.g. UK), what the motivations are and how they are made legitimate.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["758430"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["VIB", "VIB"], "EU_Contribution": ["EUR 1 706 250"], "Project_Title": ["The role of sleep in synaptic plasticity"], "Total_Cost": ["EUR 1 706 250"], "Country": ["Belgium", "Belgium"], "Project_ACR": ["SleepSynapses"], "Technology_Description": "Although we spend a third of our lives sleeping, the function of sleep remains mysterious. Studies considering neural networks, brain regions and behavior suggest the intriguing hypothesis that sleep is important for synaptic plasticity. However, as prior studies have conducted analyses using broad brain regions or circuit networks, the precise role of sleep in synaptic plasticity remains intensely debated. Progress in this area is hindered by the lack of a genetically-tractable system of sleep-dependent synaptic plasticity. To solve this, I developed a unique fruit fly model. It is the first model of its kind in which the cellular players comprising the synapses can be genetically labelled and manipulated. I will use this model to address a long-running controversy in the field--which form(s) of synaptic plasticity is promoted by sleep--by directly monitoring the effects of sleep on precisely identified synapses at electrophysiological and ultrastructural levels. Then, I will investigate the mechanisms underlying this process by analyzing the effects of sleep on every cellular component (pre and postsynaptic neurons and perisynaptic astrocytes) in this model at molecular and cellular levels. Emerging data suggest that astrocytes play a key role in synaptic plasticity and have further implicated these cells in regulating sleep. However, it has been difficult to directly examine the role of astrocytes in sleep-dependent synaptic plasticity, since no methodology currently exists for reproducibly manipulating local astrocytes enveloping the synapse of interest. For this, I will implement a unique tool, named G-CLAMP, and use it to assess potential glial mechanisms underlying sleep-dependent plasticity. Considered as a whole, my project will produce unique and comprehensive understanding of the role of sleep in synaptic plasticity, an essential question if we aim to understand sleep, and move us towards explaining the evolutionarily origins of this mysterious behavior.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Belgium"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-02-01"], "Project_ID": ["758580"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITAT AUTONOMA DE BARCELONA", "KAROLINSKA INSTITUTET", "ACIB GmbH", "AB BCN S.L.", "QUALIZYME DIAGNOSTICS GMBH & CO KG", "STOCKHOLMS LANS LANDSTING"], "EU_Contribution": ["EUR 504 000"], "Project_Title": ["New Selenium-based Targeted Nanocapsules to treat Breast Cancer"], "Total_Cost": ["EUR 504 000"], "Country": ["Spain", "Sweden", "Austria", "Spain", "Austria", "Sweden"], "Project_ACR": ["NEOSETAC"], "Technology_Description": "The European Chronic Diseases Alliance has defined cancer as one of the major non-communicable diseases, accounting for 13% of the deaths worldwide, resulting in 8.2 million deaths annually. In the NEOSETAC project, breast cancer will be the focus of study being the most common cancers in women. It comprises of 10.4% of all the cancer incidences among women, causing 411 093 deaths per year overall the world. In Europe, there is more than twice of the amount of new breast cancer cases annually than new cases of cancer in any other place. The complexity of breast cancer makes it a big challenge for successful treatment. The NEOSETAC project will demonstrate the anti-cancer therapeutic potential of a novel Seleniumbased therapy for the management of breast cancer. The clinical application of Selenium (Se) compounds for cancer treatment is until now limited in chemoprevention as dietary supplement. In this proposal, we aim to improve the therapeutic window, pharmacokinetic properties and targeting drug delivery via nanoparticles (NPs). By loading Se into biodegradable NPs, drug release is controlled within the narrow therapeutic window of Se. At the same time the uptake and activation of Se compounds at desired location (tumor lesions and metastasis) is achieved. We also propose to functionalize NPs by cancer cell / cancer stem cell targeting ligands to further improve the therapeutic efficacy and prevent cancer recurrence after chemotherapy. These advantages will lead to an enhanced anticancer activity and reduced systemic toxicity. Moreover, targeting via NPs will improve the pharmacokinetic properties and increase the relatively short half-life (~18 hours) of Se.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2018-01-01"], "Project_ID": ["778325"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["MAGYAR TUDOMANYOS AKADEMIA SZEGEDIBIOLOGIAI KUTATOKOZPONT", "MAGYAR TUDOMANYOS AKADEMIA SZEGEDIBIOLOGIAI KUTATOKOZPONT"], "EU_Contribution": ["EUR 1 486 500"], "Project_Title": ["The genetic basis of the convergent evolution of fungal multicellularity"], "Total_Cost": ["EUR 1 486 500"], "Country": ["Hungary", "Hungary"], "Project_ACR": ["Multicellularity"], "Technology_Description": "The evolution of multicellularity (MC) has been one of the major transitions in the history of life. Despite immense interest in its evolutionary origins, the genomic changes leading to the emergence of MC, especially that of complex MC (differentiated 3-dimensional structures) are poorly known. Previous comparative genomics projects aiming to understand the genetic bases of MC in one way or another relied on gene content-based analyses. However, a pattern emerging from these studies is that gene content provides only an incomplete explanation for the evolution of MC even at ancient timescales. We hypothesize that besides gene duplications, changes to cis-regulatory elements and gene expression patterns (including protein isoforms) have significantly contributed to the evolution of MC. To test this hypothesis, we will deploy a combination of computational methods, phylogenomics, comparative transcriptomics and genome-wide assays of regulatory elements. Our research focuses on fungi as a model system, where complex MC evolved convergently and in subsequent two steps. Fungi are ideal models to tackle this question for several reasons: a) multicellularity in fungi evolved multiple times, b) there are rich genomic resources (>500 complete genomes), c) complex multicellular structures can be routinely grown in the lab and d) genetic manipulations are feasible for several cornerstone species. We set out to examine which genes participate in the building of simple and complex multicellular structures and whether the evolution of regulome complexity and gene expression patterns can explain the evolution of MC better than can traditionally assayed sources of genetic innovations (e.g. gene duplications). Ultimately, our goal is to reach a general synthesis on the genetic bases of the evolution of MC and that of organismal complexity.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Hungary"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["758161"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIWERSYTET WARSZAWSKI", "UNIWERSYTET WARSZAWSKI"], "EU_Contribution": ["EUR 1 484 854"], "Project_Title": ["Urban Metamorphosis of the community of a Medieval African capital city"], "Total_Cost": ["EUR 1 484 854"], "Country": ["Poland", "Poland"], "Project_ACR": ["UMMA"], "Technology_Description": "UMMA (Arab. \u0623\u0645\u0629 - community) is a multidisciplinary project aimed as the first study of the liminal phases of a Christian African community inhabiting Dongola, the capital city of of Makuria (modern Sudan). It will concern the twilight of Christian Dongola and the metamorphosis of its urban community into a new entity organised along different social and religious paradigms. The project will investigate the impact between the weakening of the central authority and migrations of Islamic Arab tribes on the kingdom\u2019s capital city and its community. The notion that the project intends to investigate is that a complete breakdown of this urban organism and its hinterland was avoided thanks to cooperation established between the remaining local community and migrant population groups arriving in the period under consideration. The project will seek to identify strategies of", "To": ["2023-05-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Poland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-06-01"], "Project_ID": ["759926"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN", "OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN"], "EU_Contribution": ["EUR 1 499 556"], "Project_Title": ["Non-Territorial Autonomy as Minority Protection in Europe: An Intellectual and Political History of a Travelling Idea, 1850-2000"], "Total_Cost": ["EUR 1 499 556"], "Country": ["Austria", "Austria"], "Project_ACR": ["N-T-AUTONOMY"], "Technology_Description": "Over the past 150 years, non-territorial autonomy has been one of three models for dealing with linguistic or ethnic minorities within several European states. Compared with the other two, i.e. the recognition of minority rights as individual rights and territorial self-rule, non-territorial autonomy has received little attention. This project proposes to write the first history of non-territorial autonomy as an applied policy tool in minority protection and as an intellectual concept with a chequered history across Europe. Intellectuals, politicians, and legal scholars across the political spectrum from the far left to the far right supported this idea, although they were aware of the risks of strengthening national differences by promoting such a collective approach to minority protection. The project explores how this idea of granting cultural rights to a national group as a corporate body within a state, as a means of integrating diverse nationalities, travelled and transformed throughout the Habsburg Empire from 1850 to the present. We propose to 1) trace the development/circulation of theoretical conceptions and political applications of non-territorial autonomy within the Habsburg Empire, by mapping the networks of scholars as well as politicians who advocated for it; 2) explain the continuities in the development of the idea, and its manifestations in policies adopted by interwar Central and Eastern European nation states, where communists, socialists, liberals and fascists alike were able to translate elements of non-territorial autonomy into their ideologies and programs; 3) analyse the treatment of non-territorial autonomy, which was advocated by minority lobby groups, in international minority protection in the 20th century despite strong opposition to practices based on it by international organisations. We rely on a mixture of historiographical methods developed in nationalism studies to analyse the idea\u2019s translation in entangled transnational spaces.", "To": ["2023-03-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Austria"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-04-01"], "Project_ID": ["758015"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITAT AUTONOMA DE BARCELONA", "LUNDS UNIVERSITET", "UNIVERSITE DE PAU ET DES PAYS DE L'ADOUR", "UNIVERSITA DEGLI STUDI DI UDINE", "AERIS TECNOLOG\u00cdAS AMBIENTALES S.L.", "EUROPE FOR BUSINESS LTD", "UNIVERSIDAD DE LA HABANA", "CENTRO DE INVESTIGACION Y DESARROLLO DE MEDICAMENTOS"], "EU_Contribution": ["EUR 895 500"], "Project_Title": ["Removal and Recovery of Pharmaceutical Persistent Pollutants from Wastewater by Selective Reagentless Process"], "Total_Cost": ["EUR 895 500"], "Country": ["Spain", "Sweden", "France", "Italy", "Spain", "United Kingdom", "Cuba", "Cuba"], "Project_ACR": ["RECOPHARMA"], "Technology_Description": "Pharmaceutical drugs, characterized by their environmental persistence (e.g. cytostatic drugs [CDs]) have been detected in water bodies (drinking water, groundwater, surface water, and effluent wastewater) at concentrations up to \u03bcg/L level. Actual methods for the removal and degradation of CDs, including electrochemical, photochemical, and biological methods have been developed. However, these methods are expensive and sometimes inefficient for CDs complete removal from the treated water. Including the exploitation of previous results from EU funded projects, the goal of project RECOPHARMA is to design, develop, validate and demonstrate a novel process by sequential integration the potentials offered by Molecular Imprinted Polymers (MIPs), Reagentless Thermosorption (RTS), Nanocomposites Functional Materials, Advanced Oxidation Processes, for an effective treatment aiming the recovery of target recalcitrant CDs and degradation of corresponding transformation products or metabolites, working in a continuous operation mode. The suggested approach offers versatile, fast, highly efficient, and low-cost treatment for wastewaters.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-01-01"], "Project_ID": ["778266"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 494 738"], "Project_Title": ["Quantum superiority with coherent states"], "Total_Cost": ["EUR 1 494 738"], "Country": ["France", "France"], "Project_ACR": ["QUSCO"], "Technology_Description": "The unique features of quantum mechanics enable communication and computation tasks impossible to achieve by classical means. This opens a tremendous potential for enhancing the power, efficiency and security of everyday interactions in our information-based society. The quest of the demonstration in physical systems of quantum superiority has led to milestone implementations, most notably of the distribution of secret keys with unconditional security or of elementary computations such as the efficient sampling of bosonic distributions. ", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["758911"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["KAROLINSKA INSTITUTET", "KAROLINSKA INSTITUTET"], "EU_Contribution": ["EUR 1 812 500"], "Project_Title": ["Flame nanoengineering for antibacterial medical devices"], "Total_Cost": ["EUR 1 812 500"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["PROMETHEUS"], "Technology_Description": "Engineers in nanotechnology research labs have been quite innovative the last decade in designing nanoscale materials for medicine. However, very few of these exciting discoveries are translated to commercial medical products today. The main reasons for this are two inherent limitations of most nanomanufacture processes: scalability and reproducibility. There is too little knowledge on how well the unique properties associated with nanoparticles are maintained during their large-scale production while often poor reproducibility hinders their successful use. A key goal here is to utilize a nanomanufacture process famous for its scalability and reproducibility, flame aerosol reactors that produce at tons/hr commodity powders, and advance the knowledge for synthesis of complex nanoparticles and their direct integration in medical devices. Our aim is to develop the next generation of antibacterial medical devices to fight antimicrobial resistance, a highly understudied field. Antimicrobial resistance constitutes the most serious public health threat today with estimations to become the leading cause of human deaths in 30 years.", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["758705"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITETET I TROMSOE", "UNIVERSITETET I TROMSOE"], "EU_Contribution": ["EUR 1 499 749"], "Project_Title": ["Cryptophane-Enhanced Trace Gas Spectroscopy for On-Chip Methane Detection"], "Total_Cost": ["EUR 1 499 749"], "Country": ["Norway", "Norway"], "Project_ACR": ["sCENT"], "Technology_Description": "Sensitivity of on-chip gas sensors is still at least 2-3 orders of magnitude lower than what is needed for applications in atmospheric monitoring and climate research. For optical sensors, this comes as a natural consequence of miniaturization: sensitivity scales with interaction length, which is directly related to instrument size. The aim of this project is to explore a new concept of combined chemical and spectroscopic detection for on-chip sensing of methane, the principal component of natural gas and a potent climate forcer.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["758973"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["BIOSENSE INSTITUTE - RESEARCH AND DEVELOPMENT INSTITUTE FOR INFORMATION TECHNOLOGIES IN BIOSYSTEMS", "BEONCHIP SL", "UNIVERSIDAD DE ZARAGOZA", "CHERRY BIOTECH", "UNIWERSYTET JAGIELLONSKI", "ELVESYS SAS", "RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY"], "EU_Contribution": ["EUR 364 500"], "Project_Title": ["Heart On chip based on induced pluripotent Stem cell Technology for personalized Medicine"], "Total_Cost": ["EUR 364 500"], "Country": ["Serbia", "Spain", "Spain", "France", "Poland", "France", "United States"], "Project_ACR": ["CISTEM"], "Technology_Description": "Many rare diseases cause chronic health problems or are even life-threatening. The impact on the quality of life of affected patients, of whom many are children, is significant. To date, a limited but increasing number of so-called orphan drugs (drugs for rare diseases) are reaching patients. However, the majority of rare diseases are still without any effective treatment. The development of novel human systems for drug discovery therefore represents a major public health priority. Microfluidic technology-based \u201cOrgans-on-a-chip\u201d represents a powerful tool for investigating rare disease mechanisms and testing new drug and treatment due to their ability to mimic tailored micro-environment architecture inspired by organ-level functions in vivo. However, due to the variability in rare disease mechanisms from one patient to another, organ on chip technology needs to be more precise and to convey towards personalized medicine. The human-induced pluripotent stem cells (iPSCs) have a strong potential in engineering organ-on-a-chip since they are derived in a patient-matched manner which makes them a superb source to construct human models for personalized drug screening as well as for understanding patient-specific fundamentals of diseases. To provide novel miniaturized platform for investigation of rare diseases able to address the burning issues in precision medicine today, CISTEM will bring together and synergistically several highly promising research directions which are too often investigated separately at the academic level but also at the industrial level. Based on 4 work packages, the CISTEM RISE project will be implemented by exploiting the complementary expertise of its partners and creating synergies between them through the targeted secondments of staff.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Serbia"], "Activity": ["Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["778354"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["KATHOLIEKE UNIVERSITEIT LEUVEN", "KATHOLIEKE UNIVERSITEIT LEUVEN"], "EU_Contribution": ["EUR 1 452 500"], "Project_Title": ["Children in Comics: An Intercultural History from 1865 to Today"], "Total_Cost": ["EUR 1 452 500"], "Country": ["Belgium", "Belgium"], "Project_ACR": ["COMICS"], "Technology_Description": "Owing to their visual essence and status as a popular, modern medium, comics \u2013 newspaper strips, comics magazines and graphic novels \u2013 provide valuable insight into the transformation of collective consciousness. This project advances the hypothesis that children in comics are distinctive embodiments of the complex experience of modernity, channeling and tempering modern anxieties and incarnating the freedom denied to adults. In testing this hypothesis, the project constructs the first intercultural history of children in European comics, tracing the changing conceptualizations of child protagonists in popular comics for both children and adults from the mid-19th century to the present. In doing so, it takes key points in European history as well as the history of comics into account. ", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["758502"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM", "UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 1 499 750"], "Project_Title": ["From the Expression of Disagreeement to New Foundations for Expressivist Semantics"], "Total_Cost": ["EUR 1 499 750"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["EXPRESS"], "Technology_Description": "Disagreement is a pervasive feature of human life, which finds linguistic expression in the speech-act of rejection. If you assert that Amsterdam is in Belgium, I can express my dissent by responding 'No', thereby rejecting your assertion.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["758540"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["ROYAL COLLEGE OF SURGEONS IN IRELAND", "ROYAL COLLEGE OF SURGEONS IN IRELAND"], "EU_Contribution": ["EUR 1 372 135"], "Project_Title": ["Bilayered ON-Demand Scaffolds: On-Demand Delivery from induced Pluripotent Stem Cell Derived Scaffolds for Diabetic Foot Ulcers"], "Total_Cost": ["EUR 1 372 135"], "Country": ["Ireland", "Ireland"], "Project_ACR": ["BONDS"], "Technology_Description": "This program\u2019s goal is to develop a scaffold using a new biomaterial source that is functionalised with on-demand delivery of genes for coordinated healing of diabetic foot ulcers (DFUs). DFUs are chronic wounds that are often recalcitrant to treatment, which devastatingly results in lower leg amputation. This project builds on the PI\u2019s experience growing matrix from induced-pluripotent stem cell derived (iPS)-fibroblasts and in developing on-demand drug delivery technologies. The aim of this project is to first develop a SiPS: a scaffold from iPS-fibroblast grown matrix, which has never been tested as a source material for scaffolds. iPS-fibroblasts grow a more pro-repair and angiogenic matrix than (non-iPS) adult fibroblasts. The SiPS structure will be bilayered to mimic native skin: dermis made mostly by fibroblasts and epidermis made by keratinocytes. The dermal layer will consist of a porous scaffold with optimised pore size and mechanical properties and the epidermal layer will be film-like, optimised for keratinisation.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["758064"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI PADOVA", "UNIVERSITA DEGLI STUDI DI PADOVA", "ISTITUTO NAZIONALE DI GEOFISICA E VULCANOLOGIA"], "EU_Contribution": ["EUR 1 466 030"], "Project_Title": ["NEw Windown inTO Earth's iNterior"], "Total_Cost": ["EUR 1 466 030"], "Country": ["Italy", "Italy", "Italy"], "Project_ACR": ["NEWTON"], "Technology_Description": "Comprehensive seismic programs undertaken in the past few years, combined with emerging new numerical technologies now provide the potential, for the first time, to explore in detail the Earth\u2019s interior. However, such an integrated approach is currently not contemplated, which produces physical inconsistencies among the different studies that strongly bias our understanding of the Earth\u2019s internal structure and dynamics. Of particular concern are nowadays apparent thermo-petrological anomalies in tomographic images that are generated by the unaccounted-for anisotropic structure of the mantle and that are commonly confused with real thermo-petrological features. Given the diffuse mantle seismic anisotropy, apparent thermo-petrological anomalies contaminate most tomographic models against which tectono-magmatic models are validated, representing a critical issue for the present-day window.", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2018-03-01"], "Project_ID": ["758199"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["INSTITUTO NACIONAL DE INVESTIGACIONY TECHNOLOGIA AGRARIA Y ALIMENTARIA OA MP", "INSTITUTO NACIONAL DE INVESTIGACIONY TECHNOLOGIA AGRARIA Y ALIMENTARIA OA MP"], "EU_Contribution": ["EUR 1 480 880"], "Project_Title": ["Gene editing and in vitro approaches to understand conceptus elongation in ungulates"], "Total_Cost": ["EUR 1 480 880"], "Country": ["Spain", "Spain"], "Project_ACR": ["ELONGAN"], "Technology_Description": "In contrast to human or rodent embryos, ungulate embryos do not implant into the uterus right after blastocyst hatching. Before implantation, the hatched ungulate blastocyst must undergo dramatic morphological changes characterized by cell differentiation, proliferation and migration processes leading to the development of extra-embryonic membranes, the appearance of a flat embryonic disc and gastrulation. This prolonged preimplantation development is termed conceptus elongation and deficiencies on this process constitute the most frequent cause of reproductive failures in ungulates, including the 4 most relevant mammalian livestock species in Europe. The purpose of this project is to elucidate the factors involved in conceptus elongation by gene editing and in vitro culture approaches. A first objective will be to identify key genes involved in differentiation processes by RNA-seq analysis of different embryo derivatives from bovine conceptuses at different developmental stages. Subsequently, the function of some of the genes identified as well as others known to play a crucial role in mouse development or putatively involved in embryo-maternal interactions will be assessed. For this aim, bovine embryos in which a candidate gene has been ablated (KO) will be generated by CRISPR and transferred to recipient females to assess in vivo the function of such particular gene on conceptus development. A second set of experiments pursue the development of an in vitro system for conceptus elongation that would bypass the requirement for in vivo experiments. For this aim we will perform metabolomics and proteomics analyses of bovine uterine fluid at different stages and will use these data to rationally develop a culture system able to sustain conceptus development. The knowledge generated by this project will serve to develop strategies to enhance farming profitability by reducing embryonic loss and to understand Developmental Biology questions unanswered by the mouse model.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-10-01"], "Project_ID": ["757886"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER", "THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 1 494 777"], "Project_Title": ["Novel Blueprints for the Visible-Light-Mediated Assembly of C\u2013N Bonds via Nitrogen Radicals"], "Total_Cost": ["EUR 1 494 777"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["NEBULAR"], "Technology_Description": "Nitrogen-containing compounds underpin every aspect of our daily life as they form the structural basis of almost all pharmaceuticals, agrochemicals, food additives and materials. The invention of methods for the formation of bonds between C and N atoms is of strategic importance for the discovery and evolution of molecules with direct implications on the quality of our lives. Despite this fundamental relevance, forming C\u2013N bonds is still a very challenging task.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["758427"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITY OF LEEDS", "UNIVERSITY OF LEEDS"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Unravelling Multi-scale Oral Lubrication Mechanisms (macro-to-nano): A Novel Strategy to Target Satiety"], "Total_Cost": ["EUR 1 500 000"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["LubSat"], "Technology_Description": "Obesity is a serious form of malnutrition that is known to have substantial morbidity and mortality consequences. Hence, to directly promote weight management, there is an immense need to design satiety-enhancing foods that terminate appetite for longer periods after consumption. Although the concept of \u201csatiety cascade\u201d was proposed nearly 20 years ago, the changing dynamics of food properties in the oral mucosa remains the greatest source of uncertainty in food design. In particular, our quantitative multi-scale understanding of lubrication of the human salivary film when exposed to stimuli from food biomolecules, which in turn can have significant appetite suppression consequences, remains poorly understood. The key limitation to accurately measure oral lubrication is the lack of tribo-contact surfaces that effectively emulate the oral surfaces (i.e. the soft, slippery mucous-coated human tongue and the upper palate).", "To": ["2022-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["757993"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITE LIBRE DE BRUXELLES", "UNIVERSITE LIBRE DE BRUXELLES"], "EU_Contribution": ["EUR 1 579 213"], "Project_Title": ["Quadratic dispersive resonators for optical frequency comb generation"], "Total_Cost": ["EUR 1 579 213"], "Country": ["Belgium", "Belgium"], "Project_ACR": ["QuadraComb"], "Technology_Description": "Optical frequency combs are made of thousands of equally spaced spectral lines, each an ultra-stable laser in its own right. They act as \u201cspectral rulers\u201d against which unknown optical frequencies can be measured, and they have had a revolutionary impact on numerous fields ranging from the detection of extra-solar planets to precision metrology, winning its inventors a Nobel prize in 2005. Traditionally, frequency combs have been generated by ultrashort pulsed lasers, but in 2007 an important observation changed the research landscape: a continuous-wave laser coupled into a microscopic resonator was shown to spontaneously transform into thousands of comb lines via third-order nonlinear optical effects. I believe that yet another revolution lies at the horizon. Specifically, recent experiments have alluded to the possibility of realizing optical frequency combs purely through second order (quadratic) nonlinear effects. The intrinsic features of the second order nonlinearity hold promise to deliver access to new regions of the electro-magnetic spectrum beyond all conventional frequency comb technologies. But unfortunately, experimental investigations are scarce and the physics that underlie frequency comb formation in quadratic resonators is poorly understood. The goal of the QuadraComb project is to pursue a complete characterization of frequency comb generation in dispersive quadratically nonlinear resonators. I plan to (i) develop theoretical models to describe quadratic frequency combs, and (ii) develop novel platforms for the experimental realization of quadratic frequency combs.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["757800"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["STOCKHOLMS UNIVERSITET", "STOCKHOLMS UNIVERSITET"], "EU_Contribution": ["EUR 1 475 636"], "Project_Title": ["Supergene evolution in a classic plant system - bringing the study of distyly into the genomic era"], "Total_Cost": ["EUR 1 475 636"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["SuperGenE"], "Technology_Description": "Understanding how adaptive combinations of traits are maintained is a central question in evolutionary biology. Supergenes are clusters of genes that can maintain favorable trait combinations because they are inherited as a unit. Studying supergenes allows us to address fundamental questions on the origin and evolution of complex adaptations and the effects of suppressed recombination, and is therefore of broad significance.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["757451"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UPPSALA UNIVERSITET", "UPPSALA UNIVERSITET"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["SOphisticated 3D cell culture scaffolds for Next Generation Barrier-on-chip In vitro moDels"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["SONGBIRD"], "Technology_Description": "The blood-brain barrier is a sophisticated biological barrier comprising several different cell types, structured in a well-defined order with the task to strictly control the passage of molecules - such as drugs against neurodegenerative diseases - from the blood into the brain. To reduce the ethical and economic costs of drug development, which in EU today uses ~10 million experimental animals every year, we must develop in vitro models of the blood-brain barrier with high in vivo correlation, as these are completely missing today.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["757444"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH", "HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH"], "EU_Contribution": ["EUR 1 499 938"], "Project_Title": ["Astrocyte-Neuronal Crosstalk in Obesity and Diabetes"], "Total_Cost": ["EUR 1 499 938"], "Country": ["Germany", "Germany"], "Project_ACR": ["AstroNeuroCrosstalk"], "Technology_Description": "Despite considerable efforts aimed at prevention and treatment, the prevalence of obesity and type 2 diabetes has increased at an alarming rate worldwide over recent decades. Given the urgent need to develop safe and efficient anti-obesity drugs, the scientific community has to intensify efforts to better understand the mechanisms involved in the pathogenesis of obesity. Based on human genome-wide association studies and targeted mouse mutagenesis models, it has recently emerged that the brain controls most aspects of systemic metabolism and that obesity may be a brain disease. I have recently shown that like neurons, astrocytes also respond to circulating nutrients, and they cooperate with neurons to efficiently regulate energy metabolism. So far, the study of brain circuits controlling energy balance has focused on neurons, ignoring the presence and role of astrocytes. Importantly, our studies were the first to describe that exposure to a high-fat, highsugar (HFHS) diet triggers hypothalamic astrogliosis prior to significant body weight gain, indicating a potentially important role in promoting obesity. Overall, my recent findings suggest a novel model in which astrocytes are actively involved in the central nervous system (CNS) control of metabolism, likely including active crosstalk between astrocytes and neurons. To test this hypothetical model, I propose to develop a functional understanding of astroglia-neuronal communication in the CNS control of metabolism focusing on: 1) dissecting the ability of astrocytes to release gliotransmitters to neurons, 2) assessing how astrocytes respond to neuronal activity, and 3) determining if HFHS-induced astrogliosis interrupts this crosstalk and contributes to the development of obesity and type 2 diabetes. These studies aim to uncover the molecular underpinnings of astrocyte-neuron inputs regulating metabolism in health and disease so as to inspire and enable novel therapeutic strategies to fight diabetes and obesity.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["757393"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["HELSINGIN YLIOPISTO", "HELSINGIN YLIOPISTO"], "EU_Contribution": ["EUR 1 499 905"], "Project_Title": ["voCAL articuLations Of Parliamentary Identity and Empire"], "Total_Cost": ["EUR 1 499 905"], "Country": ["Finland", "Finland"], "Project_ACR": ["CALLIOPE"], "Technology_Description": "What did politicians sound like before they were on the radio and television? The fascination with politicians\u2019 vocal characteristics and quirks is often connected to the rise of audio-visual media. But in the age of the printed press, political representatives also had to \u2018speak well\u2019 \u2013 without recourse to amplification.", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["757291"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["GOETEBORGS UNIVERSITET", "GOETEBORGS UNIVERSITET"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Strong Coupling Between Molecules and Vacuum Fields: New Molecular Properties"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["STRONG"], "Technology_Description": "Chemistry has had profound impact on society during the last two centuries. From mass production of drugs and pigments, to the invention of plastics, and more recently with the introduction of molecular electronics. However, some basic physical laws govern possible utilizations. It is therefore of great importance to examine how to bend these laws, how to bypass them and by so doing open up new opportunities for novel applications.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["757733"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 144 549"], "Project_Title": ["Optical NanoActuators for Nanomachines and Microfluidic Chips"], "Total_Cost": ["EUR 144 549"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["ANTNAM"], "Technology_Description": "Over the past 2 years we have developed and patented a new actuator which is based on composite polymer/metal nanoparticles. Originally designed to create strong reversible colour changes, we found that the forces generated in the actuation exceed current microscale devices by nearly two orders of magnitude (weight for weight). We have thus protected and developed this possibility using my Advanced ERC project, LINASS, together with Cambridge Enterprise (CE, the commercialisation arm of the University of Cambridge). We have now reached the stage where we believe that this can become commercially interesting, have progressed to a better understanding of the fundamental processes, and have some idea of the applications that it might enable. The PoC project here is thus conceived to create demonstrators in two related domains: one offers new possibilities in advancing the established technology of microfluidic chips, while the other opens up a new space entirely, by making DNA nano-machines active and feasibly exploitable.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["778616"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["THE HEBREW UNIVERSITY OF JERUSALEM", "THE HEBREW UNIVERSITY OF JERUSALEM"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Highly and Widely Effective, Water Stable, and Non Toxic Titanium-Phenolato-based Anticancer Chemotherapy"], "Total_Cost": ["EUR 150 000"], "Country": ["Israel", "Israel"], "Project_ACR": ["safenolaTiCancerDrug"], "Technology_Description": "Chemotherapy is the most common line of treatment for various cancer types, but it generally suffers from severe side effects. Cisplatin is a highly effective metallodrug employed in the clinic, limited by severe and irreversible nephro- and neurotoxicities and resistance development. Therefore, developing highly and widely effective chemotherapy that is non- or substantially less- toxic should impact immediately and significantly the welfare of society. The titanium metal is an attractive Pt alternative, as it is bio-friendly and non-toxic. Titanium dioxide, the final decomposition product of Ti complexes in water, is a safe material often found in food and cosmetics. Nevertheless, the rapid dissociation of past Ti complexes in water has hampered their development into drugs.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["779689"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 477 500"], "Project_Title": ["A Scalable Quantum Network based on Individual Erbium Ions"], "Total_Cost": ["EUR 1 477 500"], "Country": ["Germany", "Germany"], "Project_ACR": ["QuantumNet"], "Technology_Description": "A future quantum network will consist of quantum processors that are connected by quantum channels, just like conventional computers are wired up to form the Internet. In contrast to classical devices, however, the entanglement and non-local correlations available in a quantum-controlled system facilitate novel fundamental tests of quantum theory and numerous applications in distributed quantum information processing, quantum communication, and precision measurement. While pioneering experiments have demonstrated the entanglement of two quantum nodes separated by up to 1.3 km, accessing the full potential of quantum networks requires scaling of these prototypes to more nodes and larger distances. To this end, a new technology that overcomes the bottlenecks of existing physical systems has to be developed.", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2018-03-01"], "Project_ID": ["757772"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["BAR ILAN UNIVERSITY", "BAR ILAN UNIVERSITY"], "EU_Contribution": ["EUR 1 487 500"], "Project_Title": ["New Directions in Lightweight Cryptanalysis"], "Total_Cost": ["EUR 1 487 500"], "Country": ["Israel", "Israel"], "Project_ACR": ["LightCrypt"], "Technology_Description": "Over the next five years, fifty billion new smart devices will be connected to the Internet of Things (IoT), creating a revolution in the way we interact with our environment. Such resource constrained devices will require lightweight cryptography to protect them and us from bad actors. Unfortunately, such schemes can be highly vulnerable: Two notable examples are the encryption schemes used in GSM cellular phones and in car remote controls - both broken by the PI. We claim that it is not sufficient to adjust the current design and analysis tools to the constrained environment. Instead, we must establish a new research methodology, aiming directly at the problems arising in the 'lightweight realm'. ", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["757731"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE", "LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE"], "EU_Contribution": ["EUR 1 488 674,14"], "Project_Title": ["Scaling Methods for Discrete and Continuous Optimization"], "Total_Cost": ["EUR 1 488 674,14"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["ScaleOpt"], "Technology_Description": "One of the most important open questions in optimization is to find a strongly polynomial algorithm for linear programming. The proposed project aims to tackle this problem by combining novel techniques from two different domains: discrete optimization and continuous optimization. We expect to contribute to exciting recent developments on the interface of these two fields. ", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["757481"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM", "THE UNIVERSITY OF BIRMINGHAM"], "EU_Contribution": ["EUR 1 481 183,75"], "Project_Title": ["A Framework for Metaphysical Explanation in Physics"], "Total_Cost": ["EUR 1 481 183,75"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["FraMEPhys"], "Technology_Description": "There is a growing consensus that causal explanation is not the whole story about explanation in science. Metaphysics has seen intense recent attention to the notion of grounding; in philosophy of physics, the focus has been on mathematical and structural explanation. But the grounding debate has been criticized for insularity and disconnection from scientific practice, while work on explanation in physics tends to overlook the sophisticated logical systems and conceptual distinctions developed in metaphysics. This situation hinders understanding of novel explanatory scenarios n philosophy of physics, where familiar models of causal explanation seem to break down. FraMEPhys addresses these challenges by combining new conceptual innovations and insights from both metaphysics and philosophy of physics to transform our understanding of the nature of explanation.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["757295"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["TECHNISCHE UNIVERSITAET GRAZ"], "EU_Contribution": ["EUR 166 156,80"], "Project_Title": ["Magnetic Enzyme Metal Organic Framework Composites"], "Total_Cost": ["EUR 166 156,80"], "Country": ["Austria"], "Project_ACR": ["MNEMONIC"], "Technology_Description": "The aim of this interdisciplinary project is to develop composites consisting of metal-organic frameworks (MOFs), magnetic nanoparticles (MNPs), and enzymes. The MOF coating protects the biomacromolecule from inhospitable conditions, and provides a permeable and selective molecular gate for the diffusion of substrates and products, thanks to its intrinsic and tunable porosity. External magnetic forces acts on the MNPs to allow for precise positioning of this ternary system. ", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["748649"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN", "OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN"], "EU_Contribution": ["EUR 1 465 316"], "Project_Title": ["CONNECTED CLERICS. BUILDING A UNIVERSAL CHURCH IN THE LATE ANTIQUE WEST (380-604 CE)"], "Total_Cost": ["EUR 1 465 316"], "Country": ["Austria", "Austria"], "Project_ACR": ["CONNEC"], "Technology_Description": "In 380 CE, the Emperor Theodosius (d. 395) ordered all Roman subjects to follow Catholic Christianity and limited imperial patronage to the Catholic Church. Theodosius was the last ruler to reign over a united empire. At his death the realm was divided into two halves, and by the end of Gregory the Great\u2019s papacy (d. 604), a mosaic of independent kingdoms had replaced the western part of the empire. Yet despite the political division, during this period western clerics built a supra-regional ecclesiastical structure with substantial levels of hierarchy and cohesion.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Austria"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["757860"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["GOLDSMITHS' COLLEGE", "GOLDSMITHS' COLLEGE"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Citizen Sense Air Monitoring Kit"], "Total_Cost": ["EUR 150 000"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["AirKit"], "Technology_Description": "In January 2013, the five-year ERC funded project Citizen Sense was launched, investigating the role of low-cost and digital monitoring technologies in facilitating and organising new types of environmental engagement. This proposal brings together a comprehensive citizen-sensing toolkit for users to undertake air quality monitoring that realises the social and environmental potential of these technologies. With the benefit of five years of intensive and cutting-edge research, the Citizen Sense research project is exceptionally well positioned to develop an AirKit, thereby bridging the gap between our research and the early stages of innovation in order to realise the innovation potential of the project. Our research pioneers new strategies of citizen-led monitoring and data analysis that join up hardware and software developments along with social innovations in order to produce an AirKit toolkit that has the potential to revolutionise community monitoring infrastructures and practices. This PoC will help to establish the viability of the AirKit, to refine and address technical issues, and to consolidate the overall direction of the AirKit.", "To": ["2019-12-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-07-01"], "Project_ID": ["779921"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["KATHOLIEKE UNIVERSITEIT LEUVEN", "KATHOLIEKE UNIVERSITEIT LEUVEN"], "EU_Contribution": ["EUR 1 947 519"], "Project_Title": ["Nanomaterials in Oncology: Exploiting the Intrinsic Cancer-Specific Toxicity of Nanoparticles."], "Total_Cost": ["EUR 1 947 519"], "Country": ["Belgium", "Belgium"], "Project_ACR": ["NANONC"], "Technology_Description": "In our current society, therapeutic strategies against cancer suffer from dose-limiting toxicity, lack of specificity and high morbidity. To overcome this, the use of nanomaterials (NMs) is rising, where several NM formulations are undergoing clinical trials or are used in clinics where the NMs are used as drug delivery vehicles or as mediators in physical anticancer methods (e.g. hyperthermia), where to date, the success rate is limited due to low tumor targeting efficacy, lack of specificity and frequent re-use of classical toxicity mechanisms.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["757398"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITA CA' FOSCARI VENEZIA", "UNIVERSITA CA' FOSCARI VENEZIA", "FONDAZIONE CENTRO EURO-MEDITERRANEO SUI CAMBIAMENTI CLIMATICI"], "EU_Contribution": ["EUR 1 495 000"], "Project_Title": ["ENERGY use for Adaptation"], "Total_Cost": ["EUR 1 495 000"], "Country": ["Italy", "Italy", "Italy"], "Project_ACR": ["ENERGYA"], "Technology_Description": "ENERGYA will improve our understanding of how energy and energy services can be used by households and industries to adapt to the risk posed by climate change. Specifically, the project will develop an interdisciplinary and scalable research framework integrating data and methods from economics with geography, climate science, and integrated assessment modelling to provide new knowledge concerning heterogeneity in energy use across countries, sectors, socioeconomic conditions and income groups, and assess the broad implications adaptation-driven energy use can have on the economy, the environment, and welfare.", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2018-03-01"], "Project_ID": ["756194"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["INSTITUT DES HAUTES ETUDES SCIENTIFIQUES", "INSTITUT DES HAUTES ETUDES SCIENTIFIQUES"], "EU_Contribution": ["EUR 1 499 912"], "Project_Title": ["Critical behavior of lattice models"], "Total_Cost": ["EUR 1 499 912"], "Country": ["France", "France"], "Project_ACR": ["CriBLaM"], "Technology_Description": "Statistical physics is a theory allowing the derivation of the statistical behavior of macroscopic systems from the description of the interactions of their microscopic constituents. For more than a century, lattice models (i.e. random systems defined on lattices) have been introduced as discrete models describing the phase transition for a large variety of phenomena, ranging from ferroelectrics to lattice gas.", "To": ["2023-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-09-01"], "Project_ID": ["757296"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["BAR ILAN UNIVERSITY", "BAR ILAN UNIVERSITY"], "EU_Contribution": ["EUR 1 372 839"], "Project_Title": ["CRISPR Gene Correction for Severe Combined Immunodeficiency Caused by Mutations in Recombination-activating gene 1 and 2 (RAG1 and RAG2)"], "Total_Cost": ["EUR 1 372 839"], "Country": ["Israel", "Israel"], "Project_ACR": ["CRISS"], "Technology_Description": "The severe combined immunodeficiencies (SCIDs) are a set of life threatening genetic diseases in which patients are born with mutations in single genes and are unable to develop functional immune systems. While allogeneic bone marrow transplantation can be curative for these diseases, there remain significant limitations to this approach. Gene therapy using viral vectors containing a corrective transgene is being developed for some of these disorders, most successfully for ADA-SCID. However, for other SCID disorders, such as those caused by genetic mutations in RAG1 and RAG2, the transgene needs to be expressed in a precise, developmental and lineage specific manner to achieve functional gene correction and to avoid the risks of cellular transformation. In contrast to using viral vectors to deliver transgenes in an uncontrolled fashion, we are working towards using genome editing by homologous recombination (HR) to correct the disease causing mutation by precisely modifying the genome. We have shown that by using clustered, regularly interspaced, short palindromic repeats (CRISPR) and the CRISPR-associated protein 9 (Cas9) system we can stimulate genome editing by HR at frequencies that should be therapeutically beneficial (>10%) in hematopoietic stem and progenitor cells (HSPCs). The overall focus of the proposal is to translate our basic science studies to use in RAG-SCID patient-derived HSPCs in methodical, careful and pre-clinically relevant fashion. The fundamental approach is to develop a highly active functional genome editing system using CRISPR-Cas9 for RAG-SCIDs and complete pre-clinical efficacy and safety studies to show the approach has a clear path towards future clinical trials. Our goal with this proposal is to develop the next wave of curative therapies for SCIDs and other hematopoietic disorders using genome editing.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["755758"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 450 000"], "Project_Title": ["Probabilistic Automated Numerical Analysis in Machine learning and Artificial intelligence"], "Total_Cost": ["EUR 1 450 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["PANAMA"], "Technology_Description": "Numerical tasks - integration, linear algebra, optimization, the solution of differential equations - form the computational basis of machine intelligence. Currently, human designers pick methods for these tasks from toolboxes. The generic algorithms assembled in such collections tend to be inefficient on any specific task, and can be unsafe when used incorrectly on problems they were not designed for. Research in numerical methods thus carries carries the potential for groundbreaking advancements in the performance and quality of AI. ", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2018-03-01"], "Project_ID": ["757275"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI VERONA", "UNIVERSITA DEGLI STUDI DI VERONA"], "EU_Contribution": ["EUR 1 233 750"], "Project_Title": ["Pre-Classical Anatolian Languages in Contact"], "Total_Cost": ["EUR 1 233 750"], "Country": ["Italy", "Italy"], "Project_ACR": ["PALaC"], "Technology_Description": "The aim of the PALaC project is to provide a systematic and complete study of language-contact in pre-classical Anatolia, from the XVIII century BCE up the Anatolian and Syro-Anatolian cultures of the Iron ages. Language contact is a specific phenomenon present in all phases of modern and historical languages, and requires to be investigated using the language-internal methodologies of contact-linguistics. The project will provide a rigorous and complete description of the linguistic interactions in ancient Anatolia, a unique historical and geographical gateway where Indo-European, Semitic and isolated languages interacted with each other, on the ideal boundary between the East and the West. PALaC will deal with the analysis of the textual data from the different Ancient Anatolian corpora, that will be assessed both from a linguistic and from philological perspective. The final results will also be integrated in the general framework of historical and cultural contact in the Ancient Mediterranean world by a dedicated work-package. The project will take advantage of the methodological expertise of a team of researchers who are well trained both in the philological study of the Ancient Near Eastern texts and in the linguistic study of languages in contact.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["757299"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS", "FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS", "CONSORZIO INTERUNIVERSITARIO PER LO SVILUPPO DEI SISTEMI A GRANDE INTERFASE", "EPISTIMONIKO PARKO PATRON AE"], "EU_Contribution": ["EUR 149 875"], "Project_Title": ["Graphene as effective anti-fading agent for the protection of artworks"], "Total_Cost": ["EUR 149 875"], "Country": ["Greece", "Greece", "Italy", "Greece"], "Project_ACR": ["GRAPHENART"], "Technology_Description": "All art materials are prone to degradation; in particular, the introduction of new creative manufacturing techniques in the 20th century art has yielded artworks with short lifetime expectancy. Fading, yellowing and discolouration are the most common degradation effects that result from the exposition to UV and visible light and oxidizing agents. The result of the degradation is the irreversible alteration of the appearance of contemporary artworks, which is a patrimony of mankind. This PoC project aims to develop innovative, multi-functional graphene-based products (graphene \u2018veils\u2019 and inclusions) that provide UV shielding, de-acidification, oxygen and humidity barriers for the protection of old and modern paintings and artworks. Recent advances in the understanding of the mechanical integrity of large graphene membranes as well as of innovative graphene-transfer processes through the current ERC Tailor Graphene has made possible the emergence of this application of strong societal value. The transparent protective graphene veil can be easily removed so it does not constitute an irreversible intervention on the art object. Moreover, for such an application the price of graphene does not hamper its business potential since the quantities are minimal. Two different classes of products are envisaged; CVD graphene membranes directly deposited to artworks for which transparency is required and graphene flakes that will be dispersed to colour paints and varnishes so as to bestow enhanced UV, oxidation and humidity resistance. The latter paves the way to extend this application to the huge market of architectural paints. A multi-disciplinary approach will be pursued for the implementation of this PoC and involves experimentation with CVD graphene sheets of various morphologies and sizes and the dispersion of nanographene as additives in paints. Finally, the development of a Business Plan will be undertaken in collaboration with business developers and patent specialists.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Greece"], "Activity": ["Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555", "Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-10-01"], "Project_ID": ["779985"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["UNIVERSITAETSKLINIKUM FREIBURG", "UNIVERSITAETSKLINIKUM FREIBURG"], "EU_Contribution": ["EUR 149 937"], "Project_Title": ["Magnetic Resonance Shimming Applications with Near-magnet Equipment"], "Total_Cost": ["EUR 149 937"], "Country": ["Germany", "Germany"], "Project_ACR": ["mrSANE"], "Technology_Description": "Magnetic resonance (MR) imaging and spectroscopy critically relies on the homogeneity of the main field. Despite of the best technological efforts magnetic field in MR examinations cannot be made homogeneous due to the presence of the object of investigation \u2013 the human or an animal \u2013 in the magnet. Heterogeneous and unique distribution of tissues with their characteristic magnetic susceptibilities requires the process of field homogenization, termed shimming, to be performed on a subject-by-subject basis. Shimming subsystems of the clinical MRI devices often show insufficient, leading to sub-optimal image quality and even failing diagnosis. Furthermore, numerous emerging methods, while showing their great potential in research settings, require even better shim fidelity. We therefore identify improved shimming as a current unmet need in MRI. Add-on hardware for more reliable shimming will greatly aid MRI research especially in the field of ultra-high imaging, such as 7T and above. A wider availability of improved shimming capabilities in the clinical machines will accelerate the transition of a multitude of current promising scientific applications of MRI to the clinical practise, allowing for a more precise diagnosis and improved patient outcomes. ", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["755466"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY", "TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY"], "EU_Contribution": ["EUR 1 432 730"], "Project_Title": ["New horizons in homogeneous dynamics and its applications"], "Total_Cost": ["EUR 1 432 730"], "Country": ["Israel", "Israel"], "Project_ACR": ["HD-App"], "Technology_Description": "We present a large variety of novel lines of research in Homogeneous Dynamics with emphasis on the dynamics of the diagonal group. Both new and classical applications are suggested, most notably to: ", "To": ["2023-09-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-10-01"], "Project_ID": ["754475"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["ISTITUTO NAZIONALE DI FISICA NUCLEARE"], "EU_Contribution": ["EUR 3 186 000"], "Project_Title": ["FELLowship for Innovation at INFN"], "Total_Cost": ["EUR 6 372 000"], "Country": ["Italy"], "Project_ACR": ["FELLINI"], "Technology_Description": "The FELLINI fellowship programme is a new, high-quality fellowship scheme based on a modern research and training approach, which aims at research excellence and promoting researcher mobility and training. FELLINI combine best practice found across the EU with a number of innovative elements that shall provide all Fellows with an ideal basis for their future careers, preparing them for a wide range of career options.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2016 - Co-funding of regional, national and international programmes"], "Funding_scheme": ["MSCA-COFUND-FP - Fellowship programmes"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["754496"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2016"]}, -{"Partners": ["BAR ILAN UNIVERSITY", "BAR ILAN UNIVERSITY"], "EU_Contribution": ["EUR 149 566"], "Project_Title": ["Voltage Nanosensors for Applications in Neuroscience"], "Total_Cost": ["EUR 149 566"], "Country": ["Israel", "Israel"], "Project_ACR": ["NiSAN"], "Technology_Description": "To understand how the brain works, tools need to be developed to allow the investigation of interactions between individual neurons. Towards this goal, We developed voltage sensing nanoparticles (vsNPs) in the shape of nanorods (vsNRs) that self-insert into the cell membrane and could optically record, non-invasively, action potentials (APs) at the single-particle and nanoscale level, at multiple sites, in a large field-of-view. The proposed nanosensors have unique advantages not offered by other methods: much larger voltage sensitivity, high brightness, and hence single-particle voltage sensitivity, large spectral shift , fast temporal response, minimal photobleaching, large two-photon excitation cross sections, excellent performance in the NIR, and compatibility with lifetime imaging.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["779896"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["WEIZMANN INSTITUTE OF SCIENCE", "WEIZMANN INSTITUTE OF SCIENCE"], "EU_Contribution": ["EUR 1 490 596"], "Project_Title": ["The Ocean's Oxygen Isotopes Deciphered: Combining Observations, Experiments and Models"], "Total_Cost": ["EUR 1 490 596"], "Country": ["Israel", "Israel"], "Project_ACR": ["OOID"], "Technology_Description": "The isotopic composition of O in seawater is a fundamental property of Earth's oceans, key to paleoclimate reconstructions and to our understanding of the origin of water on Earth, the water-rock reactions that govern seawater chemistry, and the conditions under which life emerged. Despite more than five decades of research, the geologic history of seawater 18O/16O remains a topic of intense debate. Without exception, well-preserved 18O/16O records from marine precipitates reflect both the minerals' formation temperature, and the isotopic composition of seawater. This duality has prevented unique interpretation of a long-term secular trend, in which 18O/16O in sedimentary rocks (e.g., carbonates, cherts) has increased by ~15 \u2030 since the Archean. Here I outline an inter-disciplinary research program to address this fundamental problem, which integrates new geochemical observations, laboratory experiments, and numerical models.", "To": ["2023-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["755053"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITAT DE BARCELONA"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Remembering the Sound of Images: Cross-cultural study of rock art soundscapes and knowledge transmission in the New and Old Worlds."], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["MEMORISING"], "Technology_Description": "How do societies remember? Memory is fragile and volatile and thus people around the world, and through time, have created ways to recall events and to share knowledge. ", "To": ["2020-01-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-15"], "Project_ID": ["750706"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF NOTTINGHAM", "THE UNIVERSITY OF NOTTINGHAM"], "EU_Contribution": ["EUR 149 912"], "Project_Title": ["Electrocatalytic Nanoreactors for Absorption, Detection and Decontamination of Hazardous Compounds"], "Total_Cost": ["EUR 149 912"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["NANOELECTROCHEM"], "Technology_Description": "Chemical warfare agents (CWA) are one of the most odious weapons of mass destruction, designed to incapacitate humans by causing blistering, choking, internal bleeding and vomiting on a grand scale. CWA are inexpensive and relatively easy to synthesise making them accessible to terrorist groups, providing a means for the administration of large scale damage with only small quantities of materials. Current state-of-the-art methods to detect or decontaminate CWA lack efficiency and flexibility and, with tensions in numerous war zones pushed to breaking point. By building on the fundamental scientific discoveries made in the ERC Consolidator grant (No 277784, NANOMOL), we shall extend and develop the application of electrochemically active carbon nanoreactors for the detection and decontamination of CWA, such as mustard gas and other agents. The nanoscale electrochemical platform (NANOELECTROCHEM) developed in this Proof of Concept (PoC) project is expected to be universally applicable for the triple-use (absorption + detection + decontamination) of a wide spectrum of CWA and many other harmful anthropogenic compounds, within the single platform allowing for an extremely portable device for a range of practical applications.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["754682"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["ECOLE DES HAUTES ETUDES EN SCIENCES SOCIALES"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Aural Paris: The Changing Identities of The City of Sound in Music, Film and Literature, 1870-1940."], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["Aural Paris"], "Technology_Description": "This project examines the creative assimilation of the city of Paris into the music, film and literature of the French Third Republic (1870-1940). In this period, demarcated by two war defeats, France had to find its new place within global politics, and the arts participated vividly in these debates. As the city of Paris changed rapidly from a world-leading metropolis to an impoverished city in need of architectural, political and moral reconstruction, its symbols acquired different connotations. This changing backdrop offers the ground for the study, which analyses how singer/songwriters, composers, authors and filmmakers \u2014such as Victor Fournel, Aristide Bruant, Jean Cocteau, Gustave Charpentier, Ren\u00e9 Clair and Pierre Mac Orlan\u2014 used the city and its sounds as creative force and political metaphor. The study of overlooked, or totally ignored, archival sources and cultural artefacts will enlighten our knowledge of how street culture and city life intersected with art. The proposed research plan analyses \u2018panoramic literature\u2019 in the late 19th century, the development of the city as a musical stage, the corpus of compositions about Paris, street music and sound in the transition from silent to sound cinema, and the composition of populist Parisian songs by authors of urban life-writing. The project allows us to re-evaluate the politics of the city soundscape and its role in defining French identity. It also reassesses established notions of modernity and its interaction with the urban context though the study of everyday sounds and music. By embracing novel ecomusicological methodologies, this project is timely in joining current debates within musicology and cultural geography on the capacities of sound to produce a sense of space and place. The research will create orthodox academic outputs, exploit novel dissemination and communication strategies, and consolidate an international interdisciplinary network on urban musicology.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["750086"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["DEUTSCHES INSTITUT FUR WIRTSCHAFTSFORSCHUNG DIW (INSTITUT FUR KONJUNKTURFORSCHUNG) EV"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Paternity leave and the gender gap in pay and earnings"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["PAGE"], "Technology_Description": "This project will estimate the impact of the gender split in parental leave on gender gaps in labour market outcomes and domestic work. I will address this topic, which is of Europe-wide policy relevance, by examining the parental leave policy in Germany. To provide causal estimates, I will make use of variation in the gender split in leave that is due to a cap in the income-related benefit payments at 1,800\u20ac per month. A preliminary step for the analysis, is to confirm empirically that the cap in parental leave benefits does in fact induce variation in the gender split of leave. Following on from this, the main analysis will make use of differences in the gender split in leave that result specifically from the benefit cap in order to answer two questions:", "To": ["2020-02-29, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations"], "From": ["2018-03-01"], "Project_ID": ["752053"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION"], "EU_Contribution": ["EUR 175 419,60"], "Project_Title": ["Functional exploration of the contributions of brainstem-motor thalamic pathways to motor execution and learning"], "Total_Cost": ["EUR 175 419,60"], "Country": ["Switzerland"], "Project_ACR": ["MoThal"], "Technology_Description": "Motor learning is a fundamental process enabling an organism to improve movement efficiency during a motor task. It is supported by motor cortex, which organizes movements into complex sequences. Yet, how this structure is informed of planned and generated actions is poorly understood. Anatomically, motor cortex is highly interconnected with the motor thalamus (Mthal). Interestingly, this structure is involved during the acquisition of different motor tasks, but also shows homologous roles in motor function to brainstem areas. In line with these observations, we hypothesize that pathways between the brainstem to Mthal represent an interesting and unexplored way for motor information to reach cortical areas during motor learning.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["749527"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAT KONSTANZ"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Development of novel computational biology pipeline for the efficient classification of titin SNPs for clinical use"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["TTNPred"], "Technology_Description": "Mutations in the giant muscle protein titin are a major cause of heart disorders in human populations. Routine DNA screening of patient cohorts is now becoming feasible, with a staggering number of titin truncations and missense single nucleotide polymorphisms (mSNPs) rapidly accumulating in genomics databases (>17,000 mSNPs). While the link between titin truncation and disease is now becoming clarified, detecting the pathogenic potential of mSNPs remains a substantial challenge. In mSNPs classification, bioinformatics evaluation is a necessary first filtering step, but existing predictors are poorly reliable. To address this problem, we aim to develop a new titin-centric scoring function that predicts the mechanistic effect of an mSNP exchange in the titin protein by considering the specific characteristics of its poly-domain chain. For this work, we will build a medium-throughput molecular diagnostic pipeline that harvest existent structural models of titin components in estimating mSNPs-induced changes in free energy and conformational dynamics in the protein. Calculations will be benchmarked against experimentally obtained biophysical and biochemical data. To develop this methodology, we will use a clinically pertinent training set of 75 mSNPs. However, in a subsequent step, stable predictions will be extrapolated to the rest of the titin chain by exploiting the repetition of structural and functional loci within the chain. A titin map of vulnerability \u201chot-spots\u201d so calculated will be distributed to the research community. Ultimately, we aim to produce a tool that can aid clinicians to identify patients at risk of developing a titin-based heart condition at early disease stages, where intervention is still possible.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["753054"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Photovoltaic Control and Integration"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["PVCI"], "Technology_Description": "According to the \"Europe 202 strategy\", Europe should increase the use of photovoltaics (PV) and other renewable energy sources (RES) for a sustainable future. However, to this day, PV plants are not-controllable power sources, thus imposing limits on PV penetration due to technical restrictions.", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["746638"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FUNDACION IMDEA NANOCIENCIA"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["2D magnetic materials for molecular SPINtronics"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["2DSPIN"], "Technology_Description": "Spintronics, which aims at using the spin state of electrons to process information, is a promising route to supplement conventional electronics. The field is rapidly diversifying into Molecular Spintronics where magnetic molecules are the core of the devices and Organic Spintronics where spin currents are injected from ferromagnetic metals into organic materials like graphene. The electrical control of the molecular magnetism and the spin injection are however still limited and not well understood. In my proposal 2DSPIN, I propose to push Spintronics beyond the state-of-the-art by merging new magnetic 2D materials (Fe0.25TaS2) with magnetic molecules (0D) in hybrid mixed-dimensional (0D-2D) devices. I aim to achieve a full control over the spin of individual molecules by injecting spin polarized currents from all-2D devices. The electrical addressing of the spin of magnetic molecules with spin polarized currents is expected to open a new route to address and switch the molecular spin. As a proof-of-concept of this control, my proposal aims at fabricating spin filters based on individual organic radicals linked to Fe0.25TaS2 electrodes. Along the road, I expect to achieve enhanced and robust spin injection in non-magnetic materials, like graphene, and a controlled tuning of molecular magnetic properties through the interaction with magnetic layered materials in van der Waals heterostructures. The use of intrinsically magnetic 2D materials will overcome present limitations set by technological difficulties like the oxidation, the low spin polarization of traditional ferromagnetic metals and the dimensionality mismatch between molecules and electrodes.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["746579"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE DE FRIBOURG"], "EU_Contribution": ["EUR 187 419,60"], "Project_Title": ["Identification and characterization of sites of lipid droplet biogenesis in the ER"], "Total_Cost": ["EUR 187 419,60"], "Country": ["Switzerland"], "Project_ACR": ["LD_Biogenesis"], "Technology_Description": "Lipid droplets (LDs) are evolutionarily conserved dynamic organelles dedicated to storage of fat. Relatively little is known about the molecular processes that regulate nascent LD formation at specific sites in the endoplasmic reticulum (ER). Understanding LD biogenesis and degradation is crucial for deciphering the pathophysiology of LD storage disorders, like obesity, diabetes type-2, atherosclerosis, and lipodystrophy. The main objective of this project is to precisely map and characterize LD biogenesis sites in the ER using the model eukaryote, S. cerevisiae. One reason so little is known about the earliest stages of LD biogenesis is that until recently we have not had tools to visualize and characterize these sites. However, I have generated a yeast strain in which it is possible to use electron microscopy to image the earliest stages of LD biogenesis. In a recently published study I used this strain to characterize early stages of LD biogenesis and I propose to use this strain to investigate the role of a number of proteins in LD biogenesis by using mutants lacking these proteins. In addition, I have developed the first fluorescent protein marker of sites of nascent LD biogenesis. This new protein will allow me to use fluorescent microscopy to visualize LD biogenesis in live cells and in mutants lacking proteins known to be involved in LD biogenesis. I will also use this protein as a molecular tool to identify proteins and lipids that are enriched at LD biogenesis sites in the ER by performing immuno-purification and mass-spec analyses. The proposed studies will reveal and identify proteins and lipids necessary for the earliest stages of LD biogenesis and will make possible future mechanistic studies of LD biogenesis. My participation in \u201cLD_biogenesis\u201d will broaden my scientific expertise and hone my competences in becoming a successful project investigator.", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["747536"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN"], "EU_Contribution": ["EUR 187 866"], "Project_Title": ["The Gendered Politics of Emotion in Austerity Ireland"], "Total_Cost": ["EUR 187 866"], "Country": ["Ireland"], "Project_ACR": ["GENDEMOTION"], "Technology_Description": "This research project surveys and theorises the politics of shame in the contemporary Irish context. It identifies the deployment and manipulation of emotions in public discourses, particularly with regard to historically marginalised groups, since the onset of the economic crisis, and teases out the gendered and classed operation of the politics of shame. The project establishes the role shame plays in the contemporary political setting post-2008 with the introduction of austerity as a policy-response to the economic crisis. Building on theoretical work highlighting the increased shame-proneness of traditionally disadvantaged groups, the project examines the linkage between gender and shame. Although shame has been understood to be entangled with patriarchal norms concerning women\u2019s bodies and sexuality it has, so far, not been theorised with regard to gender and material disadvantage and poverty. There is some empirical evidence that shame, does, in fact, manifest itself in impoverished populations, and that this may be amplified or at least complicated by gender. The project forms the first political theoretical treatment of the economic crisis and the policy-response to same, and focuses, uniquely, on gender and class. It will does so, again uniquely, through a framing in terms of affect and the politics of emotion. The project seeks to capture just how those experiencing austerity most immediately, conceptualise their disproportionate disadvantaging, and whether they themselves engage a politics of shame. The training and career development provisions of the project aim to enhance the researcher's profile as a specialist in gender, who is equally adept at engaging social science and humanities research methods, and facilitate a deeper probing of a complex empirical context as it relates to gender, shame, and economic disadvantage.", "To": ["2019-11-12, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-11-13"], "Project_ID": ["750326"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V."], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Light triggered non-invasive gene delivery through lipopolyplexes"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["LIGHTOPLEX"], "Technology_Description": "Target-specific and controlled drug delivery are nowadays integral and extremely promising parts of research and practice in modern medicine. It gives an option to reduce drug toxicity and increase bioavailability by delivering a drug to a specific site with defined concentration. During the last decade highly efficient non-viral gene delivery has been achieved by encapsulation of nucleic acids into complexes of liposomes and polycations - lipopolyplexes (LPP) - new generation gene delivery systems. The main challenge in liposome-based gene delivery is to achieve high level of control over gene release. The main aim of this project is to develop a new approach for non-invasive gene delivery while gene release is highly controlled in space and time. This will be achieved by the design of infra-red light sensitive LPPs. The project includes engineering of the tailor-made LPPs, detailed investigation of the light triggered release mechanism, and will eventually result in intracellular light triggered gene delivery. Expert knowledge of the researcher together with the knowledge to be contributed by the hosting institution and from collaborations established by the researcher worldwide will allow successful project implementation. Mutual knowledge transfer will strengthen scientific contacts within and outside the EU as well as will let the researcher to develop her own independent research career. Attraction of interest from industrial partners is expected in case of success. Collaboration with industrial partners will profit from an exceptional record of the host with successful industrial projects.", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations"], "From": ["2018-02-01"], "Project_ID": ["747245"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Constructing a theory of phonotactic processing during speaking"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["PhonPred"], "Technology_Description": "Languages of the world have their unique ways of putting sounds together. For example, word-initial /\u014b/ sounds bizarre to an English but not to a Cantonese speaker\u2019s ear (e.g. /\u014boi/ \u201clove\u201d). These constraints on where sounds tend to occur and how they are typically sequenced within a word are called \u201cphonotactic\u201d. Phonotactic constraints are a source of significant regularity in the sound system of any language. How do humans exploit this phonotactic regularity when they produce speech? This project will provide a general and yet unprecedented theoretical framework of how this happens in a variety of communicative situations. We will develop three converging approaches in order to achieve this goal. First, we will bring together insights from linguistic theory and computational linguistics to develop a comprehensive characterization of phonotactic dependencies in English. Second, we will investigate how phonotactic information is represented in the human mind and how it is used in speaking. To achieve this, we will generate concrete predictions using cognitive psychological models of speech production and reading aloud, thus bridging the gap between these two fields of scientific enquiry that have been long treated as independent. We will simultaneously exploit tools and tasks from cognitive psychology and experimental phonetics to test our predictions empirically through behavioural experimentation. Finally, we will capitalise on advances in the science of learning, to determine phonotactic dependencies shape the acquisition of literacy. This research will shed light on mechanisms involved in the processing of sounds during reading, speaking, and the acquisition of these skills, and will inform the development of novel methods for teaching and enhancing literacy in first and second language.", "To": ["2020-09-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-10-01"], "Project_ID": ["747987"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAETSKLINIKUM FREIBURG", "UNIVERSITAETSKLINIKUM FREIBURG"], "EU_Contribution": ["EUR 149 900"], "Project_Title": ["Disseminating N-terminomics to Advance Protease Research"], "Total_Cost": ["EUR 149 900"], "Country": ["Germany", "Germany"], "Project_ACR": ["ProteaseNter"], "Technology_Description": "Protein N-termini represent a wealth of biological information, such as their generation by limited proteolysis, which sculpts proteome functionality by yielding protein-sized cleavage products with novel functionality. N-terminomics is a branch of functional proteomics and enables the analysis of thousands of protein N-termini in an unbiased manner. By targeting native, proteolytically generated or acetylated protein N-termini as well as uncovering novel translation initiation sites, N-terminomics bears relevance to proteolysis and proteogenomics research. Unlike proteomic assays to study modifications such as phosphorylation, N-terminomics has remained inaccessible to non-expert laboratories due to a lack of ready-to-use kit formats or commercial services. Based on a recently published N-terminomic workflow by my laboratory, the present project aims to fill this niche by laying the foundation to represent N-terminomics (sample preparation up to mass spectrometry analysis) in a kit-like format together with online data analysis. Development steps include inclusion of multiple internal standards for improved sample-to-sample comparability, sole usage of cost-effective, disposable \u201csmall-scale\u201d equipment in sample preparation, minimization of required input material, adaption to different input material including cryopreserved and formalin-fixed, paraffin-embedded samples, as well as web-based mass spectrometry data analysis and annotation. This endeavor is based on multiple collaborative projects of the applicant with pharmaceutical companies and backed by interest of proteomic supply companies. In a small forward-looking activity, the project will explore the application N-terminomics in molecular diagnostics of bladder cancer; based on the rationale local infiltration by solid tumors is based on differential proteolysis. This activity serves an initial step to add N-terminomics to the toolbox of molecular pathology.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["780730"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["UNIVERSITY OF LEEDS"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Glycoprotein-based inhibitors of shiga-like toxin"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["GlypStx"], "Technology_Description": "Gastrointestinal infections have substantial impact in both the developing world and in Europe with 1.5 billion cases each year leading to approximately two million deaths each year, 760,000 of which are in children under five years old. Many of these deaths are caused by bacteria for example E. coli O157, that produces protein toxins, including shiga-like toxin (SLT). In the human body, the surfaces of living cells are covered in complex carbohydrate molecules. This \u201csugar coating\u201d allows the cells to interact with viruses, bacteria, and toxins that have complementary protein receptors. The pentagonal shiga-like toxin produced by E. coli O157 bacteria can attach to five copies of a specific carbohydrate on the gut wall and enter cells lining the intestine. The result is bloody diarrhoea and the toxin entering the circulatory system to cause kidney failure.", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["746421"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 149 875"], "Project_Title": ["Graphene-based High Resolution Neural Interfaces for ICT-inspired Neuro-treatment"], "Total_Cost": ["EUR 149 875"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["MINERGRACE"], "Technology_Description": "Electronic devices enabling communication with human nervous system are becoming increasingly prevalent, offering novel information and communication (ICT)-based treatment techniques to help people overcome various disorders ranging from spinal cord injuries (SCIs) to missing limbs. Millions of people worldwide suffer from such ailments with a cumulative cost to the society estimated in billions of Euros annually. Next-generation ICT-based treatment techniques demand for interfaces with higher spatial resolution compared to state-of-the-art. To address this demand, MINERGRACE aims to build a prototype transceiver with high spatial resolution based on nano-patterned graphene sheets (NPGSs), which can be utilised as high resolution neural interfaces (NIs) capable of differentiating and generating highly localised fluctuations in specific ion concentrations. As the project outcome, MINERGRACE will provide a proof-of-concept NPGS-based NI prototype, i.e., a portable electronic device that can be integrated with a microprocessor. High resolution aspects of the MINERGRACE project outcome will provide a very significant improvement to the state-of-the-art in terms of both the capacity of the communication and the complexity of data communicated with the nervous system, enabling the communication with individual neurons. The project outcome will have a wide spectrum of applications involving NIs, e.g., ICT-based SCI treatments and neuro-prosthesis, significantly contributing to their quality of service. Commercialisation process will involve investigation into other commercialisation activities towards other NI products, development of an understanding of intellectual property rights (IPR) positions, and strategies for patenting activities in light of the achieved understanding of IPR position. We will work with identified industrial partners and societal organisations to collaborate towards in-market positioning for delivering the product to potential end users.", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["780645"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["THE UNIVERSITY OF NOTTINGHAM"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Hopfield neural network dynamics in open quantum systems"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["HopeQNet"], "Technology_Description": "Understanding how quantum effects can improve the performance of actual computing devices is an exciting and growing research area. However their role in neural networks (NNs), the complementary information process paradigm of classical computation is largely unexplored. The full translation of this paradigm at the quantum level ultimately requires to combine disordered spin-systems techniques, widely used in the study of classical NNs, together with the open quantum systems (OQSs) framework, in order to achieve their irreversible and non-linear dynamics. HopeQNet is the first step of an ambitious program that will lead, in a long term effort, to a new generation of quantum computing architectures, and is designed to deliver a first initial theoretical framework to investigate quantum effects in NNs, by considering the open quantum generalization of one of the most celebrated paradigms of NNs, the Hopfield model. This workhorse model will be simple and rich enough to: (i) apply well-developed tools from the theory of OQSs and establish a meaningful framework for a quantum NN; (ii) evaluate the potential gain due to quantum effects in this specific quantum NN architecture; (iii) engineering and modeling a proof-of-principle experiment of a Rydberg quantum simulator implementing it. ", "To": ["2019-11-02, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-11-03"], "Project_ID": ["746442"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Multi State Memory in Artificial Multiferroics"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["MuStMAM"], "Technology_Description": "Our digital universe is doubling in size every two years, so that by 2020, it will contain nearly as many digital bits as there are stars in our physical universe! Existing memory technologies are approaching their physical storage limitations as miniaturisation of electronic devices continues. This requires significant development of advanced next generation data storage technologies to sustain consumer demand for increasing levels of data creation. New materials and technology to store more data in smaller area are required. There is a strong argument in favour of investing in multiferroic material that is still at a distance from a marketable position. In this proposed project we will investigate the prospect of exchange bias coupled artificial multiferroic material for high density memory device to overcome the market demand.", "To": ["2020-02-29, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["745886"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["TAMPEREEN YLIOPISTO"], "EU_Contribution": ["EUR 191 325,60"], "Project_Title": ["Understanding the impact of EU policies on the deinstitutionalization of child care in non-EU Eastern European countries"], "Total_Cost": ["EUR 191 325,60"], "Country": ["Finland"], "Project_ACR": ["EUCHILD"], "Technology_Description": "The project will investigate the effects of EU policies on the deinstitutionalization of child care in non-EU countries of Eastern Europe. These countries have large numbers of children in orphanages and, in recent years, have been moving towards family-based child care policies. The study will be conducted in two parts. Firstly, a unique dataset on national deinstitutionalization reforms and relevant EU interventions in Armenia, Azerbaijan, Georgia, Belarus, Moldova, Ukraine, and Russia will be gathered. After conducting a correlation analysis on these data two countries will be chosen by the positive deviance method, that is, by finding particularly successful countries. These will be further studied using in-depth interviews of NGOs, government officials and international agencies in order to understand how progress has been achieved and what combinations of factors were key to the success of the reforms. This analysis will lead to an in-depth understanding of the drivers of deinstitutionalization in these countries, and will help inform EU policies towards the region.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["742981"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON", "UNIVERSITY COLLEGE LONDON", "UNIVERSITY OF BRIGHTON"], "EU_Contribution": ["EUR 2 243 584"], "Project_Title": ["Ecological Language: A multimodal approach to language and the brain"], "Total_Cost": ["EUR 2 243 584"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom"], "Project_ACR": ["ECOLANG"], "Technology_Description": "The human brain has evolved the ability to support communication in complex and dynamic environments. In such environments, language is learned, and mostly used in face-to-face contexts in which processing and learning is based on multiple cues: linguistic (such as lexical, syntactic), but also discourse, prosody, face and hands (gestures). Yet, our understanding of how language is learnt and processed, and its associated neural circuitry, comes almost exclusively from reductionist approaches in which the multimodal signal is reduced to speech or text. ECOLANG will pioneer a new way to study language comprehension and learning using a real-world approach in which language is analysed in its rich face-to-face multimodal environment (i.e., language\u2019s ecological niche). Experimental rigour is not compromised by the use of innovative technologies (combining automatic, manual and crowdsourcing methods for annotation; creating avatar stimuli for our experiments) and state-of-the-art modelling and data analysis (probabilistic modelling and network-based analyses). ECOLANG studies how the different cues available in face-to-face communication dynamically contribute to processing and learning in adults, children and aphasic patients in contexts representative of everyday conversation. We collect and annotate a corpus of naturalistic language which is then used to derive quantitative informativeness measures for each cue and their combination using computational models, tested and refined on the basis of behavioural and neuroscientific data. We use converging methodologies (behavioural, EEG, fMRI and lesion-symptom mapping) and we investigate different populations (3-4 years old children, healthy and aphasic adults) in order to develop mechanistic accounts of multimodal communication at the cognitive as well as neural level that can explain processing and learning (by both children and adults) and can have impact on the rehabilitation of language functions after stroke.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["743035"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["FUNDACION CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III", "FUNDACION CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III"], "EU_Contribution": ["EUR 2 499 875"], "Project_Title": ["Chronic Systemic Inflammation: Functional organ cross-talk in inflammatory disease and cancer"], "Total_Cost": ["EUR 2 499 875"], "Country": ["Spain", "Spain"], "Project_ACR": ["CSI-Fun"], "Technology_Description": "Chronic Systemic Inflammation (CSI) resulting from systemic release of inflammatory cytokines and activation of the immune system is responsible for the progression of several debilitating diseases, such as Psoriasis, Arthritis and Cancer. Initially localised diseases can result in CSI with subsequent systemic spread to distant organs, a key patho-physiological phase responsible for major morbidity and even mortality. Despite the importance of CSI, a complete understanding of the molecular mechanisms, signalling pathways and cell types involved, as well as the chronological evolution of the systemic inflammatory response is still elusive. The classical approach to study inflammation has focused on investigating individual cell types or organs in the pathogenesis of a single disease, thereby neglecting important organ cross-talk and systemic interactions. Furthermore, understanding the temporal and spatial kinetics modulating the inflammatory response requires a detailed study of interactions between different immune and non-immune organs at various time points during disease progression in the context of the whole organism.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["741888"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 2 499 149"], "Project_Title": ["CLOTH manIpulation Learning from DEmonstrations"], "Total_Cost": ["EUR 2 499 149"], "Country": ["Spain", "Spain"], "Project_ACR": ["CLOTHILDE"], "Technology_Description": "Textile objects pervade human environments and their versatile manipulation by robots would open up a whole range of possibilities, from increasing the autonomy of elderly and disabled people, housekeeping and hospital logistics, to novel automation in the clothing internet business and upholstered product manufacturing. Although efficient procedures exist for the robotic handling of rigid objects and the virtual rendering of deformable objects, cloth manipulation in the real world has proven elusive, because the vast number of degrees of freedom involved in non-rigid deformations leads to unbearable uncertainties in perception and action outcomes.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["741930"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["VIB", "VIB"], "EU_Contribution": ["EUR 2 500 000"], "Project_Title": ["Preclinical concept validation of tumor endothelial cell metabolism for novel anti-angiogenic therapy"], "Total_Cost": ["EUR 2 500 000"], "Country": ["Belgium", "Belgium"], "Project_ACR": ["TECNEC"], "Technology_Description": "MAIN GOAL: To characterize the metabolic changes, fuelling growth of tumor endothelial cells (TECs) versus normal healthy endothelial cells (NECs), and identify & validate metabolic genes, deregulated in TECs, as targets for anti-angiogenic cancer therapy. ", "To": ["2022-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Belgium"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-11-01"], "Project_ID": ["743074"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI PERUGIA", "UNIVERSITA DEGLI STUDI DI PERUGIA"], "EU_Contribution": ["EUR 2 895 836"], "Project_Title": ["Improving therapy of NPM1-mutated AML"], "Total_Cost": ["EUR 2 895 836"], "Country": ["Italy", "Italy"], "Project_ACR": ["TREAT-NPM1-AML"], "Technology_Description": "Acute myeloid leukemia (AML) is the most common acute leukemia in adults accounting for approximately 15,000 new cases/year in Europe and 20,000 new cases/year in US. Currently, 40-50% of AML patients (age 18-60 years) and only 5-10% of older patients (who are usually more frequently affected by the disease) can be cured using conventional chemotherapy +/- allogeneic hematopoietic stem cell transplantation. Thus, AML still remains an urgent medical need which calls for new forms of molecular targeted therapies (similarly to those available for acute promyelocytic leukemia). The P.I. previously discovered the nucleophosmin (NPM1) mutations, the most common genetic lesion in AML (about one-third of cases) and gave fundamental contributions in the translation of this seminal discovery into the clinic (improved classification of myeloid neoplasms according to WHO, genetic-based risk- stratification of AML patients, monitoring of minimal residual disease and first demonstration of the anti-leukemic activity of actinomycin D). The present research proposal is focused on improving therapy of NPM1-mutated AML. Specifically, it is aimed to: i) identify novel chemical tools interfering with NPM1 functions by interacting with the N-terminal portion of the protein (objective 1); ii) conduct a clinical trial (AML-PG02; Eudract 2014-003490-41) with actinomycin D in older untreated and/or unfit patients with NPM1-mutated AML and to better understand in vitro and in mice models the mechanisms of action of this drug, used alone or in combination with other agents (objective 2); iii) develop compound mouse models aimed to investigate how NPM1 mutations cooperate with FLT3-ITD or DNMT3A mutations in promoting AML with the goal to better understand the characteristics of relapsed cases and to design new therapeutic strategies (objectives 3 and 4): and iv) generate a murine model for testing the feasibility of \u201cin situ\u201d vaccination in AML, especially in NPM1-mutated AML (objective 5).", "To": ["2022-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["740230"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW", "KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW"], "EU_Contribution": ["EUR 2 500 000"], "Project_Title": ["A single-cell genomics approach integrating gene expression, lineage, and physical interactions"], "Total_Cost": ["EUR 2 500 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["IntScOmics"], "Technology_Description": "From populations of unicellular organisms to complex tissues, cell-to-cell variability in phenotypic traits seems to be universal. To study this heterogeneity and its biological consequences, researchers have used advanced microscopy-based approaches that provide exquisite spatial and temporal resolution, but these methods are typically limited to measuring a few properties in parallel. On the other hand, next generation sequencing technologies allow for massively parallel genome-wide approaches but have, until recently, relied on studying population averages obtained from pooling thousands to millions of cells, precluding genome-wide analysis of cell-to-cell variability. Very excitingly, in the last few years there has been a revolution in single-cell sequencing technologies allowing genome-wide quantification of mRNA and genomic DNA in thousands of individual cells leading to the convergence of genomics and single-cell biology. However, during this convergence the spatial and temporal information, easily accessed by microscopy-based approaches, is often lost in a single-cell sequencing experiment. The overarching goal of this proposal is to develop single-cell sequencing technology that retains important aspects of the spatial-temporal information. In particular I will focus on integrating single-cell transcriptome and epigenome measurements with the physical cell-to-cell interaction network (spatial information) and lineage information (temporal information). These tools will be utilized to (i) explore the division symmetry of intestinal stem cells in vivo; (ii) to reconstruct the cell lineage history during zebrafish regeneration; and (iii) to determine lineage relations and the physical cell-to-cell interaction network of progenitor cells in the murine bone marrow.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["742225"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI PERUGIA", "UNIVERSITA DEGLI STUDI DI PERUGIA"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Commercialization of a first in class multiple sclerosis drug"], "Total_Cost": ["EUR 150 000"], "Country": ["Italy", "Italy"], "Project_ACR": ["DIDO-MS"], "Technology_Description": "Multiple sclerosis (MS) is a chronic and progressive neurodegenerative disease that is currently affecting 2.3 million people worldwide. Incidence rates of MS are significantly higher in Europe and in other regions located within the northern hemisphere. In Europe, the number of patients currently afflicted with MS is estimated to be at 700,000, with incidence rates ranging from 2.3-12.2/100,000 per year. GlobalData assessed the market value for MS treatments in 10 major markets (France, Germany, Italy, Spain, UK, US, Canada, Japan, China and India) in 2014 to be at \u20ac16.2 billion and predicts it to rise to approximately \u20ac18.82 billion by 2024. This increase is attributed to the projected sales of newly-approved drugs. The main shortcoming of current MS treatments ultimately lies in their lack of efficacy, specifically in that they are unable to prevent progressive neurodegeneration in MS patients. MS poses a significant economic burden on society as the disease affects primarily young people who are in their most economically-productive years. Aside from limited efficacies, current treatment options are also associated with severe side-effects (increased risks of infection, cancer), high costs and inconvenient administration routes (e.g. intravenous, intramuscular, subcutaneous). The aim of DIDO-MS is to assess the commercial viability of a newly identified small molecule as a drug in the treatment of MS.", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["780807"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["FACULTY OF BIOLOGY OF THE UNIVERSITY OF BELGRADE", "YEDITEPE UNIVERSITY VAKIF", "ITA-SUOMEN YLIOPISTO", "ARGENIT AKILLI BILGI TEKNOLOJILERI SANAYI VE TICARET LIMITED SIRKETI", "ELVESYS SAS", "FUNDACION CENTRO DE ALTA TECNOLOGIA", "UNIVERSITY OF CONNECTICUT", "THE UNIVERSITY OF CHICAGO"], "EU_Contribution": ["EUR 954 000"], "Project_Title": ["AUTOMATED FUNCTIONAL SCREENING OF IgGs FOR DIAGNOSTICS OFNEURODEGENERATIVE DISEASES"], "Total_Cost": ["EUR 954 000"], "Country": ["Serbia", "Turkey", "Finland", "Turkey", "France", "Costa Rica", "United States", "United States"], "Project_ACR": ["AUTOIGG"], "Technology_Description": "The project proposes to organize the exchange of staff of three Academic institutions from Serbia (coordinator), Turkey and Finland, two SMEs from France and Turkey and three TC institutions (two from USA and one from Costa Rica) towards the production of an innovative automated multifunctional device for diagnostics of neurodegenerative diseases.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Serbia"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["778405"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["UNIVERSITY OF PLYMOUTH", "CHALMERS TEKNISKA HOEGSKOLA AB", "Phranakhon Rajabhat University", "TRUONG DAI HOC TON DUC THANG", "SHENZHEN UNIVERSITY"], "EU_Contribution": ["EUR 450 000"], "Project_Title": ["Tailor-made Recycled Aggregate Concretes"], "Total_Cost": ["EUR 450 000"], "Country": ["United Kingdom", "Sweden", "Thailand", "Vietnam", "China"], "Project_ACR": ["TRAC"], "Technology_Description": "Concrete is the main construction material used on earth. The increasing population and urbanization has led to construction of new high-rise buildings and demolishing existing old low-rise ones. This has become not only the cause of natural resources depletion at an alarming rate but also gradually becoming a challenge for environmental preservation. Concrete industry consumes a majority of natural resources and produces a large amount of construction waste. In order to ensure sustainable, cost-effective but still profitable concrete production, extensive research is needed to investigate how concrete industry can produce green concrete by using less nature resources and producing less waste. The aim of the proposed research is to develop tailor-made concretes by using more recycled concrete aggregate (RCA) for structural applications. The use of RCA as granular material in pavement design has been a long history. However its use in structure concrete has not been widely accepted, primarily due to the poor quality found in RCA. To overcome this technical difficulty one has to understand the behaviour of RCA and to find a way in which the quality of the RCA can be improved and controlled during its mixing process. This requires a systematic research into various specific aspects of RCA and recycled aggregate concrete products. This proposed RISE programme is to bring together an international team of researchers with a wide variety of skills, to tackle the challenges faced by construction industry. The proposed research covers the fundamental study of cementitious materials as well as their applications in different construction fields. The outcome of the research will provide vital information on how to revolutionise the production of concrete materials and how to engineer concrete mixes using various different components to tailor-made the properties of the resulting concrete.", "To": ["2022-06-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-07-01"], "Project_ID": ["777823"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Censoring Chaucer: Canonicity and Obscenity in Manuscripts and Print Editions of the Canterbury Tales (c. 1400 - 1831)"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["Censoring Chaucer"], "Technology_Description": "This project investigates the relationship between Chaucer's canonical status and his obscenity, both of which have been closely associated with the Canterbury Tales since Chaucer's death in 1400. Readers of the Canterbury Tales have made note of its occasionally indecorous language and content (particularly in relation to sex, the body, and bodily functions) ever since the earliest surviving manuscript was compiled c. 1405. But whereas obscenity is one of the major features of Chaucer's reputation in the eyes of present-day readers, many medieval and early modern readers viewed Chaucer\u2019s obscene matter as standing at odds with his canonicity. This project traces the building tension between Chaucer's perceived obscenity and his literary reputation from his death in 1400 to the publication of poet laureate Robert Southey's expurgated version of the Canterbury Tales in 1831. By examining variations in the language and content of manuscripts, incunables, and print editions of the Canterbury Tales produced within this period (as well as reader annotations), I will show that scribes, readers, editors, and modernizers of Chaucer's most famous work persistently modify or comment on its language and content in an effort to downplay (or, occasionally, to enhance) what they perceive as obscene. I situate my findings alongside contemporaneous remarks by writers and editors regarding Chaucer's literary heritage in order to assess the relationship between variations in his reputation and variations in the Canterbury Tales. The project incorporates intensive training in the study of manuscripts and early printed books, and will result in at least 2 scholarly articles, a book proposal, and several conference presentations and public engagement initiatives intended to communicate my results to the widest possible audience. A MSCA Fellowship at the University of Oxford will enable me to work closely with a leading expert in the history of the book over the course of the project.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["741333"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["STICHTING VU", "STICHTING VU"], "EU_Contribution": ["EUR 1 999 823"], "Project_Title": ["Regulating mixed intimacies in Europe"], "Total_Cost": ["EUR 1 999 823"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["EUROMIX"], "Technology_Description": "This project is a study of the regulation of \u2018mixture\u2019(\u2018interracial\u2019 sex, relationships and marriage) in Europe\u2019s past and present. Informed by critical race and critical mixed race studies, it challenges the common assumption that Europe never had \u2018anti-miscegenation\u2019 laws comparable to those in the United States. In exploring if, when, how and why forms of regulation aiming to prevent or restrict \u2018interracial mixture\u2019 developed in Europe in certain times and places, the project delivers a vital contribution to our knowledge of the development of racial thinking in Europe. The concept of \u2018mixture\u2019 provides an eminently suitable approach to the construction of \u2018race\u2019, since \u2018mixture\u2019 confuses and destabilizes racialized categories that seem fixed and essentialized in specific times and places, such as \u2018black/white\u2019. ", "To": ["2022-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["725238"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["VILNIAUS UNIVERSITETAS", "Institute of Applied Physics of the Academy of Sciences of Moldova", "ELEKTRONIKOS PERDIRBIMO TECHNOLOGIJOS UAB", "INTREPRINDEREA MIXTA UZINA TOPAZ SA", "CLARKSON UNIVERSITY", "BELARUSIAN STATE UNIVERSITY THE RESEARCH INSTITUTE OF PHYSICAL CHEMICAL PROBLEMS"], "EU_Contribution": ["EUR 598 500"], "Project_Title": ["Multiscaled Smart Metallic and Semiconductor Electrodes for Electrochemical Processing and Devices"], "Total_Cost": ["EUR 684 000"], "Country": ["Lithuania", "Moldova", "Lithuania", "Moldova", "United States", "Belarus"], "Project_ACR": ["SMARTELECTRODES"], "Technology_Description": "Demand of \u201csmart\u201d electrodes/systems has recently increased due to significant role of various devices/equipment based on these electrodes - urgent needs of present and forthcoming human activities. The multi- and interdisciplinary project SMARTELECTRODES is proposing elaboration of advanced systems covered under umbrella of \u201csmart\u201d electrodes which will be involved and play significant roles in several important electrochemical/electrophysical applications as catalysis/electrocatalysis, sensoring, thermoelectrics, electrowinning, electrochemical machining and electrospark alloying. The development of multiscaled (from nano- to macro-; from nanodot to volumized 3D-) metallic and semiconductor electrodes and integration of them into working systems/equipment is the main target of SMARTELECTRODES. The project is well-balanced, highly innovative R&D training network, which aims: ", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Lithuania"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["778357"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["UNIVERSITAT AUTONOMA DE BARCELONA", "UNIVERSITAT AUTONOMA DE BARCELONA"], "EU_Contribution": ["EUR 1 451 264"], "Project_Title": ["Migration and Democratic Diffusion: Comparing the Impact of Migration on Democratic Participation and Processes in Countries of Origin"], "Total_Cost": ["EUR 1 451 264"], "Country": ["Spain", "Spain"], "Project_ACR": ["MIGRADEMO"], "Technology_Description": "The objective of this project is to unravel the impact of migration on democratic participation and processes in countries of origin. Both international migration and democratic development are important contemporary public and policy concerns. Recent studies of transnational migrant practices have uncovered how migrants influence democratic participation in their homelands through the remittance of money and newfound ideas about democracy from afar or through return. Yet, there is still little comparative knowledge of how these processes intersect with broader economic, social and political transformations in countries of origin. Moreover, complex migration experiences and nonlinear processes of democratization in countries of origin point to the need for a more nuanced conceptualization of what kind of political ideas circulate and are negotiated among migrants, return migrants and non-migrants in countries of origin.", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["726405"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSIDAD CARLOS III DE MADRID", "UNIVERSITE DE LORRAINE", "TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY", "INSTYTUT PODSTAWOWYCH PROBLEMOW TECHNIKI POLSKIEJ AKADEMII NAUK", "TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK", "University of Florida", "Texas A&M University", "BATTELLE MEMORIAL INSTITUTE NON PROFIT CORPORATION"], "EU_Contribution": ["EUR 153 000"], "Project_Title": ["Unraveling the role of anisotropy in material failure"], "Total_Cost": ["EUR 153 000"], "Country": ["Spain", "France", "Israel", "Poland", "United States", "United States", "United States", "United States"], "Project_ACR": ["QUANTIFY"], "Technology_Description": "The overall objective of the QUANTIFY action is to form an international network of 8 organisations, working on a joint research programme in the field of Solid Mechanics. The 8 organisations (4 European beneficiaries and 4 US partner organisations) will exchange and share skills and knowledge with the view to understand and model the effect of anisotropy in the dynamic mechanical failure of lightweight metallic materials used in the transportation and civilian-security industries. Breakthroughs in this field will allow lightweight metals fabricated with microstructure optimization techniques and additive manufacturing to replace steel and heavy alloys in manufacturing high structural responsibility components for automobiles, ships, aircrafts and civil infrastructures, all sectors of crucial importance for the European economy and society. The staff members who participate in the project will be exposed to new research environments and develop new skills, thus contributing to their increased employability and supporting research in Europe. The 8 organisations will further strengthen their knowledge base, and (further) develop lasting collaborations.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["777896"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["UNIWERSYTET MEDYCZNY IM KAROLA MARCINKOWSKIEGO W POZNANIU", "JOINT STOCK COMPANY FARMAK", "THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN", "INSTYTUT FARMACEUTYCZNY", "PHYSIOLUTION GMBH", "APPLIED PROCESS COMPANY LIMITED", "HELSINGIN YLIOPISTO", "ZENTIVA, K.S.", "RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY"], "EU_Contribution": ["EUR 2 268 000"], "Project_Title": ["Open Research Biopharmaceutical Internships Support"], "Total_Cost": ["EUR 2 268 000"], "Country": ["Poland", "Ukraine", "Ireland", "Poland", "Germany", "Ireland", "Finland", "Czech Republic", "United States"], "Project_ACR": ["ORBIS"], "Technology_Description": "The current process of drug development is lengthy and inefficient. Only 1 out of approximately 10,000 drug molecules enters the market. Therefore more effective medicines, demanded by society, cannot be provided by pharmaceutical industry. To fill this gap, Open Research Biopharmaceutical Internships Support (ORBIS) proposes that the high attrition rate of new drug candidates might be reduced by over 20% by improving early stage R&D productivity. The overarching objective of ORBIS is therefore to form an international and inter-sectoral academic and industrial network. The action is aimed at improving the preclinical pathway of medicine development concentrating on processes and technologies. The goal is to integrate multidisciplinary research by involving academia and industry from EU (Poland, Ireland, Finland, Germany and Czech Republic), EU associated country (Ukraine) and US to address the poor drug bioavailability as 70% of actives have solubility and/or membrane permeability problems. The action is addressed at selected molecules of class II and IV of Biopharmaceutics Classification System, to improve their pharmaceutical potential. The complementary consortium comprises experts in computations, physical chemistry, material science, nanotechnology, pharmacy, pharmacology and bioanalysis. The secondments will create a stimulating environment for early stage researchers to advance their individual career and soft skills. EU scientists will amalgamate their expertise in drug synthesis and dissolution, oral formulations, and bioanalytical methods with the knowledge on dermal research provided by the US partner. ORBIS will consolidate the existing links, promote long-term cooperation and exchange of knowledge between beneficiaries and partners. ORBIS will also enhance dissemination of new research outcomes and raise the awareness among the general public of the importance of drug delivery research that makes new drugs more accessible and affordable for society.", "To": ["2022-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-RISE-2017 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Poland"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["778051"], "Call_for_Proposal": ["H2020-MSCA-RISE-2017"]}, -{"Partners": ["THERAPANACEA", "THERAPANACEA"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Fast, Digital Adaptive Personalized Radiotherapy"], "Total_Cost": ["EUR 150 000"], "Country": ["France", "France"], "Project_ACR": ["TheraPanacea"], "Technology_Description": "TheraPanacea seeks to provide digital, innovative, patient-specific, and adaptive radiotherapy treatment planning system. Our objectives are the following: (i) improve the quality of treatment towards increasing the survival rate, while (ii) reducing the side effects towards diminishing the disastrous long term radiation impact and (iii) improving the efficiency of device use towards increasing significantly the number of patients being treated.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["France"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-11-01"], "Project_ID": ["737604"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["Institute of Science and Technology Austria", "Institute of Science and Technology Austria"], "EU_Contribution": ["EUR 1 498 394"], "Project_Title": ["Probing the Reversibility of Autism Spectrum Disorders by Employing in vivo and in vitro Models"], "Total_Cost": ["EUR 1 498 394"], "Country": ["Austria", "Austria"], "Project_ACR": ["REVERSEAUTISM"], "Technology_Description": "Autism Spectrum Disorders (ASD) are a group of neurological conditions characterized by stereotypical or repetitive behaviours as well as impairments in social interaction and communication skills, often of genetic basis. ASD have been classified as neurodevelopmental disorders, implying irreversible defects in the maturation of neural circuits. We have shown that mutations in the Branched Chain Ketoacid Dehydrogenase Kinase (BCKDK) gene lead to a potentially preventable and reversible form of ASD (Novarino et al. Science 2012). The most direct consequence of BCKDK mutations is a hyper-metabolism of the branched chain amino acids (BCAAs), resulting in atypically low levels of serum and brain BCAAs. Recently, using whole exome sequencing we identified individuals with ASD carrying mutations in the gene SLC7A5, encoding for the transporter mediating BCAA flux across the blood brain barrier. This suggests that the BCAAs are critical for brain development and cognition and reinforces their link with ASD. The simple nature and availability of the BCAAs prompt raising the possibility that this group of amino acids may be employed to treat symptoms of other ASD. We aim at 1) elucidating the link between BCAAs, ASD, brain development and cognition; 2) exploring the possibility of employing the BCAAs to reverse symptoms caused by mutations of ASD-genes.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["715508"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["STOCKHOLMS UNIVERSITET", "STOCKHOLMS UNIVERSITET"], "EU_Contribution": ["EUR 1 491 966,75"], "Project_Title": ["SUNMAG: Understanding magnetic-field-regulated heating and explosive events in the solar chromosphere"], "Total_Cost": ["EUR 1 491 966,75"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["SUNMAG"], "Technology_Description": "This project represents a new powerful approach to a fundamental problem in solar physics: the heating of the solar chromosphere. The aim of SUNMAG is to identify the mechanisms that heat the chromosphere and characterize the energy flux that is being released into the outer layers of the Sun in active regions and flares. By investigating how the chromosphere regulates the energy and mass transport we can also contribute to an understanding of the heating of the corona and the acceleration of the solar wind. These goals are finally within reach thanks to the recent developments of numerical simulations and analysis codes for observations and, observationally, thanks to the very recent development of a new powerful instrument for imaging spectroscopy (CHROMIS) that allows to study the upper chromosphere at the highest possible spatial resolution. ", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["759548"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITEIT LEIDEN", "UNIVERSITEIT LEIDEN"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Hypoxic Tumour Models for Photoactivatable Ruthenium-based Chemotherapy"], "Total_Cost": ["EUR 150 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["HypoRuLight"], "Technology_Description": "In this Proof-of-Concept project I will show the commercial potential of ruthenium-based photoactivated chemotherapy (PACT) compounds developed in my ERC Starting Grant by demonstrating their efficacy on hypoxic cancer models. Photoactivated chemotherapy is a new class of phototherapy to treat cancer. In principle, PACT looks similar to photodynamic therapy (PDT): light irradiation of the tumour in vivo leads to local activation of the anticancer prodrug, thereby limiting the toxicity of the treatment to the diseased tissue, and thus lowering side effects for the patient. However, the mechanisms of PACT and PDT are very different: in PDT the light-absorbing prodrug requires molecular oxygen to kill the cancer cells, whereas in PACT oxygen is not involved in prodrug activation. As a consequence, PACT agents should be able to treat hypoxic tumours, which are characterized by low oxygen concentrations and high resistance to PDT and other existing therapies. In this project the efficacy of a selection of Ru-based PACT compounds will be tested in hypoxic cancer models and compared to their efficacy in normoxic conditions. In parallel I will develop, in collaboration with my network of collaborators from the clinics, business analysts, and patent attorney, a plan for (pre) clinical development of PACT compounds.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["768166"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 1 499 611"], "Project_Title": ["Refugees are Migrants: Refugee Mobility, Recognition and Rights"], "Total_Cost": ["EUR 1 499 611"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["REF-MIG"], "Technology_Description": "This project begins with the basic premise that refugees are migrants: by legal definition and political conception, they have left their home countries to seek refuge. This project aims to re-assess refugee protection through a lens of mobility and migration, locating the study of refugee law in the context of the refugee regime. It examines the three key aspects of refugee law \u2013 access to protection, refugee status determination, and refugee rights \u2013 bringing them into conversation with the refugee regime\u2019s norms and practices on responsibility-sharing and solutions. Crucially, the project takes a long and broad view of refugee protection, in order to open up new possibilities and trajectories. It also integrates a legal assessment of the role of non-state actors in refugee protection. Using the broad notion of \u2018intermediary\u2019 in the migration process, it will assess the regulatory environment on access to protection, so-called \u2018secondary movement\u2019 and onward migration. It will provide an important legal assessment of the role of the International Organisation for Migration (IOM) and the duties of humanitarian actors in refugee protection. It addresses the EU, not as a singularity, but as an actor in the global regime.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["716968"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["Heinrich-Pette-Institute, Leibniz-Institut fuer experimentelle Virologie", "Heinrich-Pette-Institute, Leibniz-Institut fuer experimentelle Virologie"], "EU_Contribution": ["EUR 1 999 000"], "Project_Title": ["Sampling Protein cOmplex Conformational Space with native top down Mass Spectrometry"], "Total_Cost": ["EUR 1 999 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["SPOCkS MS"], "Technology_Description": "The main question to be addressed by SPOCk\u2019S MS is how protein complex conformation adapts to local changes, such as processing of polyproteins, protein phosphorylation or conversion of substrates. While labelling strategies combined with mass spectrometry (MS), such as hydrogen deuterium exchange and hydroxyl footprinting, are very versatile in studying protein structure, these techniques are employed on bulk samples averaging over all species present. SPOCk\u2019S MS will remedy these by studying the footprinting and therefore exposed surface area on conformation and mass selected species. Labelling still happens in solution avoiding gas phase associated artefacts. The labelling positions are then read out using newly developed top-down MS technology. Ultra-violet and free-electron lasers will be employed to fragment the protein complexes in the gas phase. In order to achieve the highest possible sequence and thus structural coverage, lasers will be complemented by additional dissociation and separation stages to allow MS^N. SPOCk\u2019S MS will allow sampling conformational space of proteins and protein complexes and especially report about the transient nature of protein interfaces. Constraints derived in MS will be fed into a dedicated software pipeline to derive atomistic models. SPOCk\u2019S MS will be used to study intracellular viral protein complexes, especially coronaviral replication/transcription complexes, which are highly flexible and often resist crystallisation and are barely accessible by conventional structural biology techniques.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["759661"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["WEIZMANN INSTITUTE OF SCIENCE", "WEIZMANN INSTITUTE OF SCIENCE"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Deciphering the Molecular Foundations and Functional Competence of Alternative Human Na\u00efve Pluripotent Stem Cells"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Israel", "Israel"], "Project_ACR": ["CELLNAIVETY"], "Technology_Description": "An important goal of stem cell therapy is to create \u201ccustomized\u201d cells that are genetically identical to the patient, which upon transplantation can restore damaged tissues. Such cells can be obtained by in vitro direct reprogramming of somatic cells into embryonic stem (ES)-like cells, termed induced pluripotent stem cells (iPSC). This approach also opens possibilities for modelling human diseases in vitro. However, major hurdles remain that restrain fulfilling conventional human iPSC/ESC potential, as they reside in an advanced primed pluripotent state. Such hurdles include limited differentiation capacity and functional variability. Further, in vitro iPSC based research platforms are simplistic and iPSC based \u201chumanized\u201d chimeric mouse models may be of great benefit. ", "To": ["2022-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["726497"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 1 992 578"], "Project_Title": ["Innovative technology solutions to explore effects of the microbiome on intestine and brain pathophysiology"], "Total_Cost": ["EUR 1 992 578"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["IMBIBE"], "Technology_Description": "The human gut is host to over 100 trillion bacteria that are known to be essential for human health. Intestinal microbes can affect the function of the gastrointestinal (GI) tract, via immunity, nutrient absorption, energy metabolism and intestinal barrier function. Alterations in the microbiome have been linked with many disease phenotypes including colorectal cancer, Crohn\u2019s disease, obesity, diabetes as well as neuropathologies such as autism spectrum disorder (ASD), stress and anxiety. Animal studies remain one of the sole means of assessing the importance of microbiota on development and well-being, however the use of animals to study human systems is increasingly questioned due to ethics, cost and relevance concerns. In vitro models have developed at an accelerated pace in the past decade, benefitting from advances in cell culture (in particular 3D cell culture and use of human cell types), increasing the viability of these systems as alternatives to traditional cell culture methods. This in turn will allow refinement and replacement of animal use. In particular in basic science, or high throughput approaches where animal models are under significant pressure to be replaced, in vitro human models can be singularly appropriate. The development of in vitro models with microbiota has not yet been demonstrated even though the transformative role of the microbiota appears unquestionable. The IMBIBE project will focus on using engineering and materials science approaches to develop complete (i.e. human and microbe) in vitro models to truly capture the human situation. IMBIBE will benefit from cutting edge organic electronic technology which will allow real-time monitoring thus enabling iterative improvements in the models employed. The result from this project will be a platform to study host-microbiome interactions and consequences for pathophysiology, in particular, of the GI tract and brain.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["723951"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM", "UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 1 998 004"], "Project_Title": ["Healthscaping Urban Europe: Bio-Power, Space and Society, 1200-1500"], "Total_Cost": ["EUR 1 998 004"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["HealthScaping"], "Technology_Description": "Medieval public health is mired in modern myth: without centralized governments, democratic values and advanced medicine, promoting health at the population level was purportedly either unthinkable or simply impractical. Offering a radically different view, HealthScaping will document, analyze and disseminate knowledge about preventative public healthcare between 1200-1500, an era of accelerated urbanization followed by massive demographic decline, with the onset of Black Death (1347-51). This long-term and comparative perspective will fundamentally revise the narrative of European public health by tracing the development and impact of pertinent government policies, medical discourses and social and religious action in the continent\u2019s two most urbanized and richly documented regions, Italy and the Low Countries. The project taps numerous written, material and visual sources and archaeological data from several sites, and examines them also by critically engaging the insights of governmentality studies, cultural-spatial analysis and actor-network theory. A multidisciplinary team, working in a Geographical Information Systems environment and generating innovative urban health maps, will recover earlier societies\u2019 struggles with domestic and industrial waste, travel and labor hazards, food quality, and social and religious behaviors considered harmful or dangerous. As such, the project\u2019s implications will be broad and profound, for it will 1) dislodge bio-power from its accustomed place in modernity; 2) historicize the concept of the public sphere from a health perspective; and 3) challenge the privileged role given to epidemic disease as a catalyst for environmental interventions in premodernity. It will also 4) generate new insights for public health scholars and practitioners working today around the globe, by rethinking the feasibility of preventative interventions under highly diverse forms of government, culture and topography.", "To": ["2022-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["724114"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["STICHTING VU", "STICHTING VU"], "EU_Contribution": ["EUR 1 709 240"], "Project_Title": ["Quantifying Recycling Fluxes of Earth Surface Materials and Volatiles in Subduction Zones using Melt Inclusions"], "Total_Cost": ["EUR 1 709 240"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["ReVolusions"], "Technology_Description": "Plate tectonics are fundamental to the geochemical cycles that link Earth\u2019s mantle and exosphere and in turn control the atmosphere\u2019s composition and our climate. Currently a major unknown is the exact fate of surface materials at destructive plate-tectonic boundaries (subduction zones). Specifically, what proportions of volatiles, sediments and oceanic crust are transported into the deep mantle, or are returned, i.e. \u2018recycled\u2019 to the crust and atmosphere. Global recycling flux estimates, including carbon, are contradictory highlighting the need for a new, more precise approach to their quantification.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["759563"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["ERNST-MORITZ-ARNDT-UNIVERSIT\u00c4T GREIFSWALD", "ERNST-MORITZ-ARNDT-UNIVERSIT\u00c4T GREIFSWALD"], "EU_Contribution": ["EUR 1 498 749"], "Project_Title": ["Evolution of artificial enzymes for light-driven reactions by implementing unnatural cofactors in protein scaffolds"], "Total_Cost": ["EUR 1 498 749"], "Country": ["Germany", "Germany"], "Project_ACR": ["LightZymes"], "Technology_Description": "The LightZymes project aims to create artificial enzymes (LightZymes) catalyzing selective light-driven conversions of small organic molecules.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["759262"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY", "TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Autonomous Nanosatellite-Clusters Control, Coordination and Communication Software"], "Total_Cost": ["EUR 150 000"], "Country": ["Israel", "Israel"], "Project_ACR": ["NanoC4"], "Technology_Description": "Coordinated operation of clusters of nanosatellites can potentially revolutionize the space sector; however, until recently, performing long-term satellite cluster flight was thought to be impractical, since existing orbital control methods required too much fuel. During the FADER ERC Starting Grant, our team was able to develop autonomous cluster flight algorithms capable of preserving the relative geometry and communication links among satellites in a cluster for mission lifetimes exceeding a year, while utilizing minimal amounts of fuel. Moreover, we developed cluster flight algorithms that do not require propulsion systems at all, demonstrating the usage of atmospheric drag to maintain clusters of satellites in low Earth orbits, while keeping distance constraints among satellites. Utilizing these newly-developed algorithms, nanosatellite clusters can yield the performance of a conventional large satellite for a fraction of the cost, and greatly improve mission and/or science return. The FADER algorithms were subsequently implemented as a prototype on SAMSON, the first triple-nanosatellite autonomous cluster flight mission, scheduled to be launched in 2018.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["779754"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["UNIVERSIDAD PABLO DE OLAVIDE", "UNIVERSIDAD PABLO DE OLAVIDE", "AKSE HENDRIK"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Enhancing Separation Efficiency in European Syngas Industry by using Zeolites"], "Total_Cost": ["EUR 150 000"], "Country": ["Spain", "Spain", "Netherlands"], "Project_ACR": ["ZEOSEP"], "Technology_Description": "Syngas is traditionally used in industry for production of fuels in the kerosene, gasoline and diesel range via Fischer-Tropsch, for the manufacture of bulk chemicals like ammonia, methanol and dimethyl ether and for synthesis of a whole array of fine chemicals. The hydrogen /carbon monoxide ratio of the syngas is an important design variable to maximize production of these compounds. Therefore, the search of effective processes that enable said ratio adjustment as well as individual compound purification is an essential and ongoing effort for industry. The Proof of Concept that we propose is the development of a zeolite-based separation process to obtain carbon dioxide-neutral fuels and chemicals. The process that we plan to design is based on gas uptake and release, combining separation efficiency with low separation costs. Our approach consists of three main steps: identification of the optimal zeolite structure; validation with experiments and initiation of commercialization by developing a Business Case. For the technical testing, we will use the research knowledge developed within the ERC-RASPA project, and the resulting process will be validated for the separation of carbon dioxide, carbon monoxide and oxygen resulting from plasma-assisted dissociation of the former gas into the others. The competitive analysis, business case and commercialization will be performed with the Company Traxxys Innovation and Sustainability as a partner. End user companies and equipment manufacturers such as Bronswerk (NL) and Hidralia (Sp) have expressed their interest in the idea.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-01-01"], "Project_ID": ["779792"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA", "UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["IN VItro Cavitation Through UltraSound"], "Total_Cost": ["EUR 150 000"], "Country": ["Italy", "Italy"], "Project_ACR": ["INVICTUS"], "Technology_Description": "Disorders of the central nervous system (CNS) contribute almost 800 billion euros in annual European healthcare costs. New compounds, effective in animal models, hardly work in humans, mostly due to the inability to cross the Brain Blood Barrier (BBB). In these conditions cost-effective tools to alter BBB and, more generally, endothelial layer permeability is desirable before proceeding to expensive and time-consuming animal studies. INVICTUS (IN VItro Cavitation Through UltraSound) originates within the ERC-AdG project Bubbles from Inception to Collapse (BIC) and concerns the development of a biomimetic micro-fluidic platform to be made turnkey available to biologists, clinicians and pharmacologists. The integrated platform exploits endothelial layer permeability enhancement by cavitation bubbles and provides an integrated, low cost platform to develop cavitation enhanced drug delivery under well controlled and reproducible conditions. Its potential is significant, given the well known societal and economical impact of degenerative diseases and the enormous investment and the long times of pre-clinical trials, as confirmed by a leading company operating in the field. Limiting/avoiding animal experimentation has an evident ethical impact and is associated with substantial economic savings and organisational simplification. In few words, micro-bubbles injected into the bloodstream undergo volume oscillations under localised ultrasound irradiation, with local reversible permeability enhancement of the endothelium. Already pursed in in vivo animal models, this approach is extended here to a high-fidelity, in vitro biomimetic device that will bring to market new crucial features such as the three-dimensional geometry of realistic-size vascular channels featuring an actual endothelial barrier, the correct perfusion rate, the appropriate physiological shear stress exerted on the endothelial cells and the ability to reproduce biochemical interactions between different, healthy and diseased, tissues.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["779751"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["STOCKHOLMS UNIVERSITET", "STOCKHOLMS UNIVERSITET"], "EU_Contribution": ["EUR 1 299 165"], "Project_Title": ["Micro Heterogeneity and Macroeconomic Policy"], "Total_Cost": ["EUR 1 299 165"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["MICROTOMACROANDBACK"], "Technology_Description": "This project will develop macroeconomic models with household heterogeneity and partially demand-determined output to study how the economy is affected by monetary and fiscal policy, and to investigate the importance of housing in macroeconomic fluctuations and the transmission and efficacy of policy. The objective is to provide a modelling framework that simultaneously is consistent with both empirical micro evidence on household consumption and savings behaviour, and macro evidence on the response of the aggregate economy to a variety of economic shocks. The ultimate goal is to help make these models the new standard for the study of fluctuations and policy evaluation in macro.", "To": ["2022-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["759482"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["TECHNISCHE UNIVERSITAET BERGAKADEMIE FREIBERG", "TECHNISCHE UNIVERSITAET BERGAKADEMIE FREIBERG", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 499 145"], "Project_Title": ["A Multiscale Dislocation Language for Data-Driven Materials Science"], "Total_Cost": ["EUR 1 499 145"], "Country": ["Germany", "Germany", "France"], "Project_ACR": ["MuDiLingo"], "Technology_Description": "Crystalline defects in metals and semiconductors are responsible for a wide range of mechanical, optical and electronic properties. Controlling the evolution of dislocations, i.e. line-like defects and the carrier of plastic deformation, interacting both among themselves and with other microstructure elements allows tailoring material behaviors on the micro and nanoscale. This is essential for rational design approaches towards next generation materials with superior mechanical properties.", "To": ["2022-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2017-11-01"], "Project_ID": ["759419"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["WEIZMANN INSTITUTE OF SCIENCE", "WEIZMANN INSTITUTE OF SCIENCE"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Fighting Anxiety with Importin-based Therapeutics"], "Total_Cost": ["EUR 150 000"], "Country": ["Israel", "Israel"], "Project_ACR": ["FAITh"], "Technology_Description": "Anxiety and stress-related conditions represent a significant health burden in modern society. Anxiety disorders are currently treated with a variety of agents targeting synaptic mechanisms. These agents either directly affect neurotransmitter receptor systems or modulate neurotransmitter levels or availability, but their long-term use is limited by problematic side effects and suboptimal efficacy. The development of new anxiolytic drugs has been fraught with difficulty, hence there is a need for new targets and new avenues for therapeutic development.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["767058"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["CIIMAR - Centro Interdisciplinar de Investiga\u00e7\u00e3o Marinha e Ambiental", "CIIMAR - Centro Interdisciplinar de Investiga\u00e7\u00e3o Marinha e Ambiental"], "EU_Contribution": ["EUR 1 462 938"], "Project_Title": ["Fatty acid incorporation and modification in cyanobacterial natural products"], "Total_Cost": ["EUR 1 462 938"], "Country": ["Portugal", "Portugal"], "Project_ACR": ["FattyCyanos"], "Technology_Description": "Known, but mostly novel natural products (NPs) are in high demand \u2013 these are used in drugs, cosmetics and agrochemicals and serve also as research tools to probe biological systems. NP structures inspire chemists to develop new syntheses, and NP biosynthetic enzymes add to the metabolic engineer\u2019s toolbox. The advent of next generation DNA-sequencing has revealed a vastly rich pool of NP biosynthetic gene clusters (BGCs) among bacterial genomes, most of which with no corresponding NP. Hence, opportunities abound for the discovery of new chemistry and enzymology that has the potential to push the boundaries of chemical space and enzymatic reactivity. Still, we cannot reliably predict chemistry from BGCs with unusual organization or encoding unknown functionalities, and, for molecules of unorthodox architecture, it is difficult to anticipate how their BGCs are organized. It is the valuable, truly novel chemistry and biochemistry that lies on these unexplored connections, that we aim to reveal with this proposal. To achieve it, we will work with a chemically-talented group of organisms \u2013 cyanobacteria, and with a specific structural class \u2013 fatty acids (FAs) \u2013 that is metabolized in a quite peculiar fashion by these organisms, paving the way for NP and enzyme discovery. On one hand, we will exploit the unique FA metabolism of cyanobacteria to develop a feeding strategy that will quickly reveal unprecedented FA-incorporating NPs. On the other, we will scrutinize the intriguing biosynthesis of three unique classes of metabolites that we have isolated recently and that incorporate and modify FA-moieties. We will find the BGCs for these compounds and dissect the functionality involved in such puzzling modifications to uncover important underlying enzymatic chemistry. This proposal is a blend of discovery- and hypothesis-driven research at the NP chemistry/biosynthesis interface that draws on the experience of the PI\u2019s work on different aspects of cyanobacterial NPs.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Portugal"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["759840"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["FONDAZIONE TELETHON", "FONDAZIONE TELETHON"], "EU_Contribution": ["EUR 1 497 250"], "Project_Title": ["Dissecting the regulatory logic of cell fate reprogramming through integrative and single cell genomics"], "Total_Cost": ["EUR 1 497 250"], "Country": ["Italy", "Italy"], "Project_ACR": ["CellKarma"], "Technology_Description": "The concept that any cell type, upon delivery of the right \u201ccocktail\u201d of transcription factors, can acquire an identity that otherwise it would never achieve, revolutionized the way we approach the study of developmental biology. In light of this, the discovery of induced pluripotent stem cells (IPSCs) and cell fate conversion approaches stimulated new research directions into human regenerative biology. However, the chance to successfully develop patient-tailored therapies is still very limited because reprogramming technologies are applied without a comprehensive understanding of the molecular processes involved.", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-03-01"], "Project_ID": ["759154"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITA CA' FOSCARI VENEZIA", "UNIVERSITA CA' FOSCARI VENEZIA"], "EU_Contribution": ["EUR 1 343 175"], "Project_Title": ["Florilegia Syriaca. The Intercultural Dissemination of Greek Christian Thought in Syriac and Arabic in the First Millennium CE"], "Total_Cost": ["EUR 1 343 175"], "Country": ["Italy", "Italy"], "Project_ACR": ["FLOS"], "Technology_Description": "FLOS will focus on the metamorphoses of Greek Christian thought in Syriac (Aramaic) and Arabic in Late Antiquity, within the timeframe of the first millennium CE. Syriac Christianity was a pivotal mediator of culture in the Late Antique epistemic space, but is little-known today. FLOS aims to bring to light for the first time a body of highly relevant Syriac and Christian Arabic sources that have hardly ever been studied before. At the end of the millennium, in Islamic-ruled Syria, Mesopotamia, and Iran, Syriac Christians strived to define their religious identity. One of their strategies was the production of florilegia, i.e. anthologies that they used to excerpt and reinvent the patristic canon, a corpus of Greek Christian works of the 2nd\u20136th centuries shared by European and Middle Eastern Christian cultures. A Greco-centric bias has prevented scholars from viewing these florilegia as laboratories of cultural creativity. FLOS will reverse the state of the art through two groundbreaking endeavours: 1) open-access digital editions of a set of Syriac florilegia of the 8th\u201310th centuries; 2) a study of many neglected writings of Syriac and Christian Arabic authors of the 8th\u201311th centuries. These tremendously important writings drew from Syriac patristic florilegia to pinpoint topics like incarnation and the Trinity against other Christians or Islam, showing how patristic sources were used to create new knowledge for the entangled environment of the Abbasid era. FLOS will thus dramatically improve our understanding of the cultural dynamics of Late Antiquity; patristic Christianity will emerge as a bridge between the intellectual history of Europe and of the Middle East. By studying how this shared patrimony was transformed in situations of interreligious interaction, especially with Islam, FLOS will facilitate the comprehension of Europe\u2019s current religious discourses, and the preservation of the endangered cultural heritage of the Syriac Christians.", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["758732"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSIDAD CARLOS III DE MADRID", "UNIVERSIDAD CARLOS III DE MADRID"], "EU_Contribution": ["EUR 1 497 506,87"], "Project_Title": ["Opening a new route in solid mechanics: Printed protective structures"], "Total_Cost": ["EUR 1 497 506,87"], "Country": ["Spain", "Spain"], "Project_ACR": ["PURPOSE"], "Technology_Description": "Dynamic fragmentation of metals is typically addressed within a statistical framework in which material and geometric flaws limit the energy absorption capacity of protective structures. This project is devised to challenge this idea and establish a new framework which incorporates a deterministic component within the fragmentation mechanisms. ", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["758056"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM", "THE UNIVERSITY OF BIRMINGHAM", "UNIVERSITY OF LEEDS", "STICHTING WAGENINGEN RESEARCH"], "EU_Contribution": ["EUR 1 493 970"], "Project_Title": ["Redefining the carbon sink capacity of global forests: The driving role of tree mortality"], "Total_Cost": ["EUR 1 493 970"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom", "Netherlands"], "Project_ACR": ["TreeMort"], "Technology_Description": "Everything that lives must die. Yet when it comes to the world's forests, we know much more about the processes governing their life than those governing their death. Global forests hold enormous amounts of carbon in their biomass, which has absorbed about 20% of anthropogenic carbon dioxide emissions over recent decades. Whether the size of this sink will persist, intensify, decrease or even become a source is highly uncertain, yet knowing this is crucial to the calculation of carbon emission budgets consistent with limiting global temperature rise. One of the most compelling explanations for this uncertainty is a lack of knowledge of how tree mortality affects forest carbon storage on a global scale. Mortality rates and mechanisms are closely tied to forest structure and composition, and thus the storage of carbon in biomass, but mechanistic complexity and the difficulty of measurement have hindered understanding, resulting in a striking lack of consensus in existing assessments. TreeMort will remedy this, combining newly available sources of data with appropriate conceptualisation and innovative modelling, to provide quantifications of the rates and causes of tree death, and their relation to environmental drivers, that set new standards for robustness, comprehensiveness and consistency at the global scale. This breaking-out of the narrower foci of previous work will be a game-changer, finally enabling globally-comprehensive investigation of the extent to which whole forest structure and function are governed by and interact with mortality, and their likely evolution under environmental change. TreeMort will assess this using state-of-the-art ecosystem modelling, which will then be employed to make a fundamental reassessment of the current and future carbon storage capacity of global forests. TreeMort will thus bring us significantly closer to understanding fully how forests interact with the global carbon cycle, assisting efforts to mitigate climate change.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2018-02-01"], "Project_ID": ["758873"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 499 940"], "Project_Title": ["Charge And Spin in TopologicaL Edge States"], "Total_Cost": ["EUR 1 499 940"], "Country": ["France", "France"], "Project_ACR": ["CASTLES"], "Technology_Description": "Topology provides mathematical tools to sort objects according to global properties regardless of local details, and manifests itself in various fields of physics. In solid-state physics, specific topological properties of the band structure, such as a band inversion, can for example robustly enforce the appearance of spin-polarized conducting states at the boundaries of the material, while its bulk remains insulating. The boundary states of these \u2018topological insulators\u2019 in fact provide a support system to encode information non-locally in \u2018topological quantum bits\u2019 robust to local perturbations. The emerging \u2018topological quantum computation\u2019 is as such an envisioned solution to decoherence problems in the realization of quantum computers. Despite immense theoretical and experimental efforts, the rise of these new materials has however been hampered by strong difficulties to observe robust and clear signatures of their predicted properties such as spin-polarization or perfect conductance.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-02-01"], "Project_ID": ["758077"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Charting the space of Conformal Field Theories: a combined nuMerical and Analytical aPproach"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["CFT-MAP"], "Technology_Description": "Conformal Field Theory (CFT) was originally conceived in four and three dimensions, with applications to particle physics and critical phenomena in mind. However, it is in two dimensions that the most spectacular results have been obtained. In higher dimensions, there used to be a general feeling that the constraining power of conformal symmetry by itself is insufficient to tell nontrivial things about the dynamics. Hence the interest in various additional assumptions. This is not fully satisfactory, since there are likely many CFTs that do not fulfill any of them.", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["758903"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["INSTITUT PASTEUR", "INSTITUT PASTEUR"], "EU_Contribution": ["EUR 1 489 147"], "Project_Title": ["Competition for Space in Development and Diseases"], "Total_Cost": ["EUR 1 489 147"], "Country": ["France", "France"], "Project_ACR": ["CoSpaDD"], "Technology_Description": "Developing tissues have a remarkable plasticity illustrated by their capacity to regenerate and form normal organs despite strong perturbations. This requires the adjustment of single cell behaviour to their neighbours and to tissue scale parameters. The modulation of cell growth and proliferation was suggested to be driven by mechanical inputs, however the mechanisms adjusting cell death are not well known. Recently it was shown that epithelial cells could be eliminated by spontaneous live-cell delamination following an increase of cell density. Studying cell delamination in the midline region of the Drosophila pupal notum, we confirmed that local tissue crowding is necessary and sufficient to drive cell elimination and found that Caspase 3 activation precedes and is required for cell delamination. This suggested that a yet unknown pathway is responsible for crowding sensing and activation of caspase, which does not involve already known mechanical sensing pathways. Moreover, we showed that fast growing clones in the notum could induce neighbouring cell elimination through crowding-induced death. This suggested that crowding-induced death could promote tissue invasion by pretumoural cells.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["758457"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE"], "EU_Contribution": ["EUR 1 499 996"], "Project_Title": ["Bacterial persister regrowth"], "Total_Cost": ["EUR 1 499 996"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["RESUSCITATION"], "Technology_Description": "This proposal aims to provide insight into persister resuscitation. Persisters are multidrug-tolerant cells that are transiently non-growing and able to generate viable offspring by resuming growth when antibiotic pressure is removed. Despite their implication in relapses of many infectious diseases, and progress in understanding how persisters form through the action of toxin-antitoxin modules, the mechanisms underlying resuscitation of these persisters are still unknown. The interaction between Salmonella and host macrophages has proven to be a powerful and relevant model to study persister biology since the bacteria specifically respond to engulfment by the host defence cells by forming high proportions of persisters. Upon encounter with the host, Salmonella activates 14 toxins to arrest growth and persist in this environment. With the recent discovery of a detoxifying enzyme (Pth) counteracting the action of a persister-inducing toxin (TacT), thus allowing growth resumption of Salmonella persisters, we can now begin to address the pending question of persister regrowth. The consolidation of my research group around the experimental plan proposed here, will enable us to dissect the balance between intoxication vs. detoxification or entry vs. exit from persistence induced by Tact and Pth respectively. This is the first couple of toxin/detoxifying enzymes to be identified. I intend to extend this knowledge to the whole repertoire of toxins involved in Salmonella persister formation through systematic identification and characterization of the detoxifying mechanisms allowing resuscitation. Additionally I will investigate the lag phase leading to regrowth of persisters; and target the toxins involved in persister formation to force persisters out of growth arrest. This work will unravel persister resuscitation and could ultimately provide ways to force persisters out of that state so they become re-sensitized to antibiotics.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["757369"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITEIT TWENTE", "UNIVERSITEIT TWENTE"], "EU_Contribution": ["EUR 1 499 691"], "Project_Title": ["Scaling up behavior and autonomous adaptation for macro models of climate change damage assessment"], "Total_Cost": ["EUR 1 499 691"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["SCALAR"], "Technology_Description": "Damage associated with climate change is a core benchmark in science and policy. Macro Integrated Assessment Models estimating damages are criticized for neglecting risk distribution, adaptation dynamics and the possible collapse of regional economies. Micro-level social science studies contain substantial knowledge on individual behavior, decisions under risk and autonomous climate adaptation, and go beyond monetary losses by focusing on resilience. This knowledge can ameliorate theoretical and empirical flaws in current macro assessments, if adequate scaling up methods were to exist. ", "To": ["2023-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["758014"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["CORK INSTITUTE OF TECHNOLOGY"], "EU_Contribution": ["EUR 187 866"], "Project_Title": ["Training in Quantum Photonics Design Fabrication and Characterisation"], "Total_Cost": ["EUR 187 866"], "Country": ["Ireland"], "Project_ACR": ["TeRrIFIC"], "Technology_Description": "The efficient generation of Quantum states of light is a vital task in Quantum Photonics technologies. Current approaches are generally bulky and expensive with low generation rates. The state of art solutions do not scale.", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["749143"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ITA-SUOMEN YLIOPISTO", "ITA-SUOMEN YLIOPISTO"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Novel algorithm for treatment planning of patients with osteoarthritis"], "Total_Cost": ["EUR 150 000"], "Country": ["Finland", "Finland"], "Project_ACR": ["ALGOA"], "Technology_Description": "Osteoarthritis (OA) is a common joint disease affecting over 40 million Europeans. Most common consequences of OA are pain, disability and social isolation. What is alarming, the number of patients will increase 50% in developed countries during the next 20 years. Moreover, the economic costs of OA are considerable since 1) direct healthcare (hospital admissions, medical examinations, drug therapy, etc.) and 2) productivity costs due to reduced performance while at work and absence from work have been estimated to be between 1% and 2.5% of the gross domestic product (GDP) in Western countries.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["755037"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 1 499 940"], "Project_Title": ["Mushroom Body Expansion in Heliconius butterflies"], "Total_Cost": ["EUR 1 499 940"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["MuBoEx"], "Technology_Description": "The brain plays a central role in the production of adaptive behaviour. It must extract and integrate the most relevant sensory cues from the environment, and combine this information with memories of past experience to trigger appropriate behavioural responses. To fully understand the origins of behavioural novelty we need a detailed understanding of how behavioural differences are generated, both across evolutionary time and during development. This requires the integration of behavioural and neuroanatomical variation, and their genomic and developmental bases.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["758508"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["ALBERT-LUDWIGS-UNIVERSITAET FREIBURG", "ALBERT-LUDWIGS-UNIVERSITAET FREIBURG"], "EU_Contribution": ["EUR 1 499 101"], "Project_Title": ["Emergence of Surface Roughness in Shaping, Finishing and Wear Processes"], "Total_Cost": ["EUR 1 499 101"], "Country": ["Germany", "Germany"], "Project_ACR": ["ShapingRoughness"], "Technology_Description": "Roughness on most natural and man-made surfaces shares a common fractal character from the atomic to the kilometer scale, but there is no agreed-upon understanding of its physical origin. Yet, roughness controls many aspects of engineered devices, such as friction, adhesion, wear and fatigue. Engineering roughness in surface finishing processes is costly and resource intensive. Eliminating finishing steps by controlling roughness in primary shaping or in subsequent wear processes could therefore revolutionize the way we manufacture, but this requires a deep understanding of the relevant processes that is presently lacking. Roughness emerges during mechanical deformation in processes such as folding, scratching or chipping that shape surfaces. Deformation occurs in the form of avalanches, individual bursts of irreversible motion of atoms. The central hypothesis of this project is that roughness is intrinsically linked to these deformation avalanches, which themselves are well-documented to be fractal objects. This hypothesis will be tested in large-scale atomic- and mesoscale simulations of plastic forming and fracture on state of the art high performance computing platforms. Results of these calculations will be used to develop process models for evolving the topography of large surface areas under the action of an external mechanical force, such as experienced in shaping, finishing or wear. In addition to these simulations, a public repository for sharing topography data will be build. This repository is the connection to experiments: It is a database of experimental topographies whose contents will be mined for features identified in simulations. Beyond the present project, this web-repository will advance sharing, visualization and analysis of topography data, and aid researchers to correlate surface topography with surface functionality and processing. Simulations and database lay the foundation for a rational design of surface functionality in manufacturing.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["757343"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Regulation of Single Hematopoietic Stem Cells by Intake of Vitamin A"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["VitASTEM"], "Technology_Description": "Quiescence preserves the self-renewal capacity and the long-term function of hematopoietic stem cells (HSCs). The regulators of this dormant state include intrinsic pathways and soluble components in the bone marrow niche. Dysregulation of this process is poorly defined and might cause aberrant hematopoiesis. In my previous work, we defined the molecular landscape of HSCs by applying state of the art DNA-methylome, RNA-seq and proteome analyses, and found vitamin A/retinoic acid (RA)-induced signaling predominantly enriched in HSCs (Cabezas-Wallscheid et al., Cell Stem Cell 2014). Intriguingly, we observed that mice fed with a vitamin A-free diet exhibited a robust loss of HSCs (Cabezas-Wallscheid et al., Cell 2017). Treatment of mice with a RA agonist preserved HSC quiescence in stress-activated conditions, indicating that the balance between HSC maintenance and differentiation is tightly regulated by vitamin A signaling. ", "To": ["2023-04-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2018-05-01"], "Project_ID": ["759206"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["MONTANUNIVERSITAT LEOBEN", "MONTANUNIVERSITAT LEOBEN"], "EU_Contribution": ["EUR 1 499 679"], "Project_Title": ["Design of Phase Transition Kinetics in Non-Equilibrium Metals"], "Total_Cost": ["EUR 1 499 679"], "Country": ["Austria", "Austria"], "Project_ACR": ["TRANSDESIGN"], "Technology_Description": "The first technological use of non-equilibrium phase transitions in metals for designing properties is documented as ~800 BC, but the time has come to make a leap forward. Nearly all classes of materials show non-equilibrium phase transitions. Understanding how fast these transitions occur is a key question in materials science. In metals, kinetics is connected to diffusion via atomic lattice vacancies. However, there is no universal sound and predictive physical understanding of the kinetics under non-equilibrium situations so far, because theory cannot be verified experimentally. The in-situ measuring of non-equilibrium vacancy evolution is not possible at industrially relevant and controlled high thermal rates today. Moreover, direct microscopic observation of vacancies in bulk metals has not yet been achieved.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["757961"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Dynamic control of assembly, directonnality and chirality in hydrogen bond networks."], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["DYNASSEMBLY"], "Technology_Description": "By combining biology's information storage and replication strategies, namely specific hydrogen-bonding between nucleobases, with the potential for hydrogen-bond reorganisation in novel 'refoldable foldamers', we propose to develop a new, artificial but bio-inspired mechanism for the transfer of information in chemical systems. Based on preliminary modelling studies, we will focus on one type of polyurea structures, built from 'Nowick'-style motifs, which spontaneously fold in solution, forming intramolecular polarized hydrogen-bond networks. Upon addition of simple chemical additives forming competitive intermolecular hydrogen bonds with the foldamer, the directionality of these networks could be modified, transforming a conformational mixture to a well-defined unidirectional network. Molecular events such as reversible switching, chemical sensing, and long-distance information communication will be studied. Then, biomimetic additives such as nucleobases will be investigated, and their impact on the folding of the oligomers will be analysed. We will also investigate 3D hydrogen bond networks, which will provide highly functionalised, well-defined macromolecules in a bottom-up approach, and study the change of macromolecular structure and chirality upon stimulus. Finally, structures that give a non-spectroscopic 'readout' of the interaction with the additive will be built, which for example exhibit 'off-on' fluorescence or 'off-on' catalytic activity. The application of these foldamers in the construction of photochemically switchable molecular devices will also be investigated.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["745476"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 498 000"], "Project_Title": ["Insular cortical circuits controlling fear and anxiety"], "Total_Cost": ["EUR 1 498 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["InsularAnxiety"], "Technology_Description": "How do emotions guide our behaviour? For an appropriate behavioural response, an individual has to constantly integrate bodily feelings, emotional states, and cues from the environment to evaluate the risks and benefits of a future action. A growing body of evidence indicates that the insular cortex, as part of a distributed neuronal network, plays a key role in influencing emotional behaviour. However, how neuronal circuits within the insular cortex function mechanistically is not known.", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2018-03-01"], "Project_ID": ["758448"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["KING'S COLLEGE LONDON", "KING'S COLLEGE LONDON"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Development of a Novel Computational Toolbox for Stochastic Electronic Structure in Chemistry and Condensed Matter"], "Total_Cost": ["EUR 1 500 000"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["WFNQMC"], "Technology_Description": "Atomistic computational modelling is increasingly an integral component of almost all areas of chemistry, physics and materials science, especially as its predictive ability improves. However, not all systems are equal when it comes to the predictive capabilities of current methods, and many systems are too large or many-body effects too complex to be routinely tractable. The result is that the promise of \u2018materials by design\u2019, deduction of reaction pathways or routine simulation on a par with experimental accuracy has not in general come to fruition. This ambitious proposal aims to address this, with development of a suite of novel approaches to stochastically sample the wavefunction. Recent work by the PI has already made huge strides in this direction, with an emerging approach in quantum chemical space having remarkable success for accurate solutions of small problems. Here, we first propose a number of novel developments to order to extend this approach from a tool for small systems to a widespread disruptive technology, with application to a variety of challenging problems. This involves development of the scope, scaling, accuracy and capabilities of this sampling, including admitting time-dependent, spectral and relativistic extensions. Next, we aim to take the successful philosophy of this sampling and exploit its powerful approach in order to reformulate a number of well-established electronic structure tools. Allowing stochasticity has the potential to yield low-scaling formulations of these methods, able to naturally exploit inherent sparsity, and have a revolutionary impact on their use and success. This proposal is highly interdisciplinary, spanning a range of applications and techniques in quantum chemistry, condensed matter and materials science, brought together under the banner of exploiting inherent sparsity by establishing a new paradigm of stochastic tools for correlated electrons, with the opportunity for tremendous impact in a number of fields.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["759063"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 1 499 756"], "Project_Title": ["Harnessing Non-Covalent Interactions for Control of Regioselectivity and Site-Selectivity in Catalysis"], "Total_Cost": ["EUR 1 499 756"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["NonCovRegioSiteCat"], "Technology_Description": "Nature has been employing attractive non-covalent interactions for billions of years to enable the chemical synthesis machinery of life that is enzymatic catalysis. In comparison, synthetic chemists have only very recently started to employ the very strongest, hydrogen bonds and ion pairs, to control selectivity in synthetic routes. This has occurred predominantly in the rapidly growing of enantioselective organocatalysis and has quickly had a huge impact. The vision of this grant is to take these insights and apply them to control of two more important aspects of selectivity facing the synthetic chemist \u2013 regioselectivity (positional selectivity within a particular functional group) and site-selectivity (within a wider molecule). These selectivity aspects are particularly relevant due to the increasing number of methods for functionalisation of C-H bonds, in which the overarching challenge is obtaining selectivity for one in the presence of many. ", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["757381"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITE DU LUXEMBOURG", "UNIVERSITE DU LUXEMBOURG"], "EU_Contribution": ["EUR 1 687 458"], "Project_Title": ["Predicting the effects of gut microbiota and diet on an individual\u2019s drug response and safety"], "Total_Cost": ["EUR 1 687 458"], "Country": ["Luxembourg", "Luxembourg"], "Project_ACR": ["BugTheDrug"], "Technology_Description": "Precision medicine is an emerging paradigm that aims at maximizing the benefits and minimizing the harm of drugs. Realistic mechanistic models are needed to understand and limit heterogeneity in drug responses. Consequently, novel approaches are required that explicitly account for individual variations in response to environmental influences, in addition to genetic variation. The human gut microbiota metabolizes drugs and is modulated by diet, and it exhibits significant variation among individuals. However, the influence of the gut microbiota on drug failure or drug side effects is under-researched. In this study, I will combine whole-body, genome-scale molecular resolution modeling of human metabolism and human gut microbial metabolism, which represents a network of genes, proteins, and biochemical reactions, with physiological, clinically relevant modeling of drug responses. I will perform two pilot studies on human subjects to illustrate that this innovative, versatile computational modeling framework can be used to stratify patients prior to drug prescription and to optimize drug bioavailability through personalized dietary intervention. With these studies, BugTheDrug will advance mechanistic understanding of drug-microbiota-diet interactions and their contribution to individual drug responses. I will perform the first integration of cutting-edge approaches and novel insights from four distinct research areas: systems biology, quantitative systems pharmacology, microbiology, and nutrition. BugTheDrug conceptually and technologically addresses the demand for novel approaches to the study of individual variability, thereby providing breakthrough support for progress in precision medicine.", "To": ["2023-03-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Luxembourg"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-04-01"], "Project_ID": ["757922"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 496 730"], "Project_Title": ["High-Resolution Imaging and Spectroscopy of Exoplanets"], "Total_Cost": ["EUR 1 496 730"], "Country": ["France", "France"], "Project_ACR": ["HiRISE"], "Technology_Description": "Atmospheric composition provides essential markers of the most fundamental properties of exoplanets, such as their formation mechanism or internal structure. New-generation exoplanet imagers have been designed to achieve high contrast for the detection of young giant planets in the near-infrared, but they only provide very low spectral resolutions (R<100) for their characterization. For a major breakthrough in the comprehension of young exoplanets and their atmospheres, an increase of a factor 100 to 1000 in spectral resolution is absolutely required.", "To": ["2022-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-12-01"], "Project_ID": ["757561"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA", "UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA", "CONSIGLIO NAZIONALE DELLE RICERCHE", "DHITECH DISTRETTO TECNOLOGICO HIGH-TECH SCARL"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["A holographic microscope for the immersive exploration of augmented micro-reality"], "Total_Cost": ["EUR 150 000"], "Country": ["Italy", "Italy", "Italy", "Italy"], "Project_ACR": ["ADMIRE"], "Technology_Description": "Virtual reality, augmented reality and mixed reality are beginning to transform the way we explore and acquire information from the macroscopic world around us. At the same time, recent advances in holographic microscopy are providing new tools for the 3D imaging of physical and biological phenomena occurring at the micron scale. Project ADMIRE will combine this two emerging technologies into the first prototype of an AugmenteD MIcro-REality system for the immersive exploration and the quantitative analysis of three-dimensional processes at the micron scale.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-11-01"], "Project_ID": ["780333"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["UNIVERSITEIT LEIDEN", "UNIVERSITEIT LEIDEN"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Precise array of proton selective nanopores in 2D atomically thin membranes"], "Total_Cost": ["EUR 150 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["NANOPORE"], "Technology_Description": "Direct methanol fuel cells (DMFCs) are devices expected to power future micro and portable electronic devices as well as vehicles. The lack of efficient proton exchange membranes, however, still prevents the development and application of DMFCs. Of paramount importance is ion selectivity and fast transmembrane transport, for which nanoporous two-dimensional membranes offer the prospect of enhanced fuel cell performance. Several chemical and physical limitations have so far prohibited the wide usage of atomically thin nanopores membranes, most particularly because the process of nanopore formation still lacks a reproducible, scalable and industrially viable fabrication approach. The main goal of this proposal is to develop and finally commercialize such a membrane with precise array of functional nanopores. In this proposal, based on the knowledge and experience resulting from our ERC project [project no. 335879], we will employ a novel two steps approach based on organic and supramolecular chemistry to synthesize atomically thin proton exchange membrane bearing a chemically well-defined array of nanopores and we will control the functionality of the nanopore rim by using specific chemical modifications on the backbones of monomers used to form the high selectivity proton exchange membrane (PEM). If the testing and technical reports are successful, the resulting PEM will be used in DMFC field and other related area, such as desalination and osmosis electricity generation.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["780004"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["TURUN YLIOPISTO", "TURUN YLIOPISTO"], "EU_Contribution": ["EUR 2 498 606"], "Project_Title": ["Ancestral environmental exposures and offspring health \u2013 a multigenerational epidemiologic cohort study across 3 generations"], "Total_Cost": ["EUR 2 498 606"], "Country": ["Finland", "Finland"], "Project_ACR": ["MULTIEPIGEN"], "Technology_Description": "MULTIEPIGEN seeks to solve does ancestral exposure to various stressors transmit to offspring via epigenetic mechanisms. Thus far animal models have indicated that exposure to certain stressors can lead to phenotypic changes not only in the predisposed individuals, but also in the future generations, such that individuals can acquire phenotypes caused by exposures of their ancestors. Such effects do not involve new DNA mutations, but are transmitted to offspring via epigenetic mechanisms such as the transfer of non-coding RNA molecules in the semen. In humans, intergenerational transmission has been examined extremely little because a priori designed population-based studies across several generations are lacking. To close this gap MULTIEPIGEN will expand the well-characterized Cardiovascular Risk in Young Finns Study (YFS) to the parents and offspring of the original YFS participants. During the ERC funding period, we will perform field studies involving N~9000 individuals across 3 generations and test 3 key ancestral exposures with very high plausibility causing intergenerational effects on obesity-related phenotypes, cognitive function and psychological well-being. The studied exposures are 1) tobacco smoke, 2) persistent organic pollutants, and 3) accumulation of psychosocial adversities. We will collect serum, blood and semen samples for epigenetic marker analysis to provide understanding of the mechanisms of intergenerational transmission in humans. Specifically, we will seek proof for the hypothesis that paternal stressors can lead to phenotypic changes in the offspring via non-coding RNA molecules in the semen. Multigenerational epidemiologic data showing robust links between ancestral exposures and offspring phenotypes that operate with biologically plausible epigenetic mechanism would provide a conceptual change in the developmental biology in humans and have substantial ramifications on public health.", "To": ["2022-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["742927"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "THE REGENTS OF THE UNIVERSITY OF CALIFORNIA"], "EU_Contribution": ["EUR 269 857,80"], "Project_Title": ["The workings of metacognition in decision-making"], "Total_Cost": ["EUR 269 857,80"], "Country": ["United Kingdom", "United States"], "Project_ACR": ["Meta_Mind"], "Technology_Description": "Decision-making is one of the most fundamental parts of our daily life. Undoubtedly, when having to select a course of action reflective monitoring and control of our decision process (metacognition) is of crucial importance. For instance, when a doctor has to make a medical decision, information from different sources are being accrued and combined to form a diagnosis (e.g., information from MRI images and from the anamnesis), but when a doctor is uncertain about the quality of the decision additional tests can be considered. Despite the importance of effective decision-making in all aspects of life, it\u2019s currently unclear how our metacognitive system operates and how common factors such as sleepiness and tiredness, well known to induce fragmentation of cognition, influence our metacognitive abilities. In sum, at the moment it remains unclear how and when we are capable of knowing that we know and knowing how we perform.", "To": ["2021-01-01, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-02"], "Project_ID": ["704361"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["MATERIALISE NV"], "EU_Contribution": ["EUR 160 800"], "Project_Title": ["Flexible and open-source tool for accurate reconstruction using industrial X-ray computed tomography"], "Total_Cost": ["EUR 160 800"], "Country": ["Belgium"], "Project_ACR": ["FlexCT"], "Technology_Description": "Our ability to achieve breakthroughs in manufacturing is dependent on our capacity to measure the features that define these breakthroughs. In other words, we can manufacture only as well as we can measure. Recent trends indicate that the future of mass production is in additive manufacturing (AM). X-ray computed tomography (CT) is the optimal solution for quantitative inspection of AM products as it is currently the only technology that can perform non-destructive measurements of both internal and external features. However, the reliability of CT measurements is not yet established and the application of CT for product inspection is limited to qualitative tasks. FlexCT is a multi-disciplinary research project that answers the imminent need to bring CT to measurement maturity to keep the pace with the improvements and wider adoption of AM. The fields of dimensional metrology, software engineering, and manufacturing are combined to produce an effective and open solution for the decisive adoption of CT to inspection of AM and other high-value products. ", "To": ["2019-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-SE - Society and Enterprise panel"], "Coordinated_in": ["Belgium"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-12-01"], "Project_ID": ["752672"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 974 526"], "Project_Title": ["Homotopy Theory of Moduli Spaces"], "Total_Cost": ["EUR 974 526"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["HToMS"], "Technology_Description": "Moduli spaces are spaces which describe all mathematical objects of some type. This proposal concerns the study of certain moduli spaces via techniques from homotopy theory, from several different points of view. The main moduli spaces in which we are interested are moduli spaces of manifolds, or equivalently classifying spaces of diffeomorphism groups of manifolds. We are also interested in spaces of positive scalar curvature metrics on smooth manifolds, which we study by relating them to moduli spaces of smooth manifolds.", "To": ["2023-09-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-10-01"], "Project_ID": ["756444"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITE DE GENEVE", "UNIVERSITE DE GENEVE"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Three Indirect Probes of Lyman continuum LEakage from galaxies"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["TRIPLE"], "Technology_Description": "Cosmic reionization corresponds to the period in the history of the Universe during which the predominantly neutral intergalactic medium was ionised by the emergence of the first luminous sources. Young stars in primeval galaxies may be the sources of reionization, if the ionising radiation, called Lyman continuum (LyC), that they produce can escape their interstellar medium: the escape fraction of LyC photons from galaxies is one of the main unknowns of reionization studies. This ERC project will contribute to answer this question, by computing from simulated galaxies three indirect diagnostics of LyC leakage that were recently reported in the literature, and comparing the virtual observables with the direct escape of LyC photons from simulated galaxies, and with observations. The first diagnostic for LyC leakage relates the escape of the strongly resonant Lyman-alpha radiation from galaxies to the LyC escape. It was proposed by the PI (Verhamme et al. 2015), and recently validated by observations (Verhamme et al. 2016). The second diagnostic proposes that the strength of Oxygen lines ratios can trace density-bounded interstellar regions. It was the selection criterion for the successful detection of 5 strong Lyman Continuum Emitters from our team (Izotov 2016a,b). The third diagnostic relates the metallic absorption line strengths to the porosity of the absorbing interstellar gas in front of the stars. The increasing opacity of the intergalactic medium with redshift renders direct LyC detections impossible during reionisation. Indirect methods are the only probes of LyC leakage in the distant Universe, and the proposed diagnostics will soon become observables at the redshifts of interest with JWST. They have passed the validation tests, it is now urgent to calibrate these indicators on state-of-the art simulations of galaxy formation. This is the main objective of the proposed project.", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["757258"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["FORSCHUNGSZENTRUM JULICH GMBH", "FORSCHUNGSZENTRUM JULICH GMBH"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Versatile and Innovative Detector for Electron Optics"], "Total_Cost": ["EUR 150 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["VIDEO"], "Technology_Description": "The VIDEO project will professionalize and integrate software and develop open standard file formats for electron microscopy based on results from the ERC Advanced Grant project IMAGINE, supplemented with results and support from other research groups and hardware vendors. Our goal is to combine these separate activities into an open software platform and to develop open standards, which will enable vendors and users to develop interoperable solutions in this area, and to explore business and sustainability models.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["780487"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER", "FERMI RESEARCH ALLIANCE LLC"], "EU_Contribution": ["EUR 251 857,80"], "Project_Title": ["Searching for new physics with liquid argon time projection chambers and developing the technology for the future of neutrino physics"], "Total_Cost": ["EUR 251 857,80"], "Country": ["United Kingdom", "United States"], "Project_ACR": ["LARNUEXP"], "Technology_Description": "The field of neutrino physics is an exciting one to be involved in at the moment. Neutrinos are the most mysterious fundamental, interacting so weakly with other matter that they are elusive to measurements. They also offer the only known indicators of physics beyond the Standard Model. I will use this fellowship to build expertise in the technology that will define the future of the field of neutrino physics - the liquid argon time projection chamber (LAr-TPC). I will spend the outgoing phase at Fermilab, USA, installing and commissioning the SBND detector, and working with data from SBND and the existing MicroBooNE detector. I have a track-record of pioneering searches for new physics, and will continue this by searching for a new Z boson that could be an explanation for the g-2 anomaly. I will also capitalise on my involvement in the protoDUNE liquid argon test-beam experiment, taking the protoDUNE data and applying it to the SBND and MicroBooNE detector simulations, to bring a new level of precision to the experiment. I have particular expertise in the reconstruction of low-energy electromagnetic showers. I will combine this expertise with the new protoDUNE data to develop new algorithms to enable MicroBooNE and SBND to investigate the MiniBooNE low-energy excess and search for sterile neutrinos. In the return year, I will bring my expertise in LAr-TPC technology back to the UK, and take a leading role in setting up a major production site for making anode planes for the DUNE far detector.", "To": ["2021-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Other"], "From": ["2018-03-01"], "Project_ID": ["752309"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Development of a high-performance nanofluidic osmotic diode for efficient voltage-driven desalination and pumping"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["NanoOsmDiode"], "Technology_Description": "Water scarcity is an urgent global challenge and one of the greatest societal threats posed by climate change. Despite growing concern over water availability, processes to expand water supplies beyond current freshwater reserves, such as desalination and wastewater reclamation, still suffer from insufficient rejection of contaminants and relatively high energy requirements. Nanofluidic technologies have the potential to revolutionize water treatment owing to the extraordinary transport characteristics of confined pores. The objective of the proposed project is to develop a new nanofluidic device\u2014the osmotic diode\u2014for voltage-driven desalination and pumping. To control water and ion transport, the device requires a nanopore with tailored asymmetric surface charge. An applied voltage difference can be used to drive water molecules through the nanopore while ions are rejected, desalinating source water. The system is advantageous because permeability and selectivity properties can be tuned based on nanopore characteristics, and it offers improved versatility compared to existing desalination processes. To realize the technology, the proposed work will (i) fabricate a single pore osmotic diode with tailored surface charge, (ii) characterize water transport across such a nanopore utilizing ultrasensitive flow measurement techniques, and (iii) use knowledge from the single pore system to scale up performance to many-pored membranes. Throughout the project, advanced modeling techniques will be utilized to fundamentally understand transport and further optimize the system. The proposed research action will address Horizon 2020 Societal Challenges related to water security and resource efficiency while advancing the field of nanotechnology through the development of new fabrication and flow measurement methods. The research action will also represent the first proof-of-concept for an osmotic diode system and lay the foundation for further commercialization of the process.", "To": [""], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": [""], "Project_ID": ["743637"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF NOTTINGHAM", "THE UNIVERSITY OF NOTTINGHAM"], "EU_Contribution": ["EUR 1 971 468"], "Project_Title": ["Three-Dimensional Mapping Of a Single Hydrogen Bond"], "Total_Cost": ["EUR 1 971 468"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["3DMOSHBOND"], "Technology_Description": "All properties of matter are ultimately governed by the forces between single atoms, but our knowledge of interatomic, and intermolecular, potentials is often derived indirectly. ", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["757720"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITEIT UTRECHT", "UNIVERSITEIT UTRECHT"], "EU_Contribution": ["EUR 2 205 493,75"], "Project_Title": ["Intergroup toleration: It\u2019s Nature, Processes, and Consequences for Culturally Diverse Societies"], "Total_Cost": ["EUR 2 205 493,75"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["InTo"], "Technology_Description": "Increasingly our societies are becoming more diverse and how to live with this diversity is one of the most pressing questions of our time. In Europe, intergroup tolerance has been proposed as a key aspect of living harmoniously and productively with diversity; it is critical because objection and disagreement about what is good and right are inevitable. A diverse, egalitarian, and peaceful society does not require that we all like each other, but it does require that people at least tolerate one another. Yet, there has been very little by way of social psychological theorizing and systematic empirical research on intergroup toleration. ", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["740788"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITE DE NAMUR ASBL", "UNIVERSITE DE NAMUR ASBL"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["CANITEST: Proof-Of-Concept of a PCR test designed to identify the dogs carrying the more virulent strains of Capnocytophaga canimorsus"], "Total_Cost": ["EUR 150 000"], "Country": ["Belgium", "Belgium"], "Project_ACR": ["CANITEST"], "Technology_Description": "The idea to be taken as proof of concept is drawn from the ERC Advanced grant N\u00b0293605-CAPCAN (2012-2016). This grant aimed at understanding the molecular and genetic bases of the dramatic human infections caused by Capnocytophaga canimorsus. One of the questions that we addressed in the frame of CAPCAN is why are there so few cases of human infections while so many dogs carry C. canimorsus? In other words, are all C. canimorsus strains equally dangerous and, if not, could we prevent the disease by detecting the dogs carrying the more dangerous strains? During CAPCAN, among others, we showed that C. canimorsus is endowed with a capsular polysaccharide (CPS) and its assembly pathway was characterized [1]. We also showed that the CPS of 25/25 strains isolated from human infections present a limited variability, with 3 dominant capsular serovars. In contrast, only 4 out of 52 C. canimorsus isolated from dog mouths did belong to these three serovars [2]. This implies that a small minority of dog-hosted C. canimorsus strains are virulent for humans than most strains and that these strains can be identified by capsular serotyping. We also set up a PCR test to achieve this capsular serotyping [2]. The proposal to be taken to proof of concept is to market the PCR test designed to identify the dogs carrying the more virulent strains of C. canimorsus.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["780540"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM", "ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM", "UNIVERSITEIT LEIDEN"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Triple negative breast cancer control through synergistic inhibition of EGFR and CDK9 signaling"], "Total_Cost": ["EUR 150 000"], "Country": ["Netherlands", "Netherlands", "Netherlands"], "Project_ACR": ["TRIPLECON"], "Technology_Description": "Triple negative breast cancer (TNBC) is an aggressive disease, accounting for 15-20% of breast cancer cases, but disproportionally causing breast cancer-related death. TNBC does not express the targetable receptors ER, PR, and HER2 that are known to drive other forms of breast cancer. Mainstay practice for TNBC in the clinic is to treat with non-targeted cytotoxic chemotherapies. Long-term outcomes are however still poor, most likely owing to intrinsic drug resistance. Clinical trials have attempted to explore molecular targeted therapies to block dysregulated growth factor receptors in TNBC, for instance, epidermal growth factor receptor (EGFR), as it is overexpressed in ~80% of TNBC. Yet, giving the long-standing availability of clinically approved EGFR-targeted therapies, such as lapatinib, the clinical benefit of single agent therapy is unsatisfactory, owing to the compensatory dysregulated signaling pathways. In our ongoing ERC \u2013 Advanced Grant Triple-BC (#322737) we are striving to explore combinatorial molecular targeted therapies to concomitantly block the identified dysregulated signaling pathways. Our preliminary work revealed that an inhibitor targeting cyclin-dependent kinase 9 (CDK9) strikingly synergized with targeting EGFR receptor family signaling to inhibit cell proliferation of TNBC cell lines. The overall goal of this PoC project is to exploit this novel finding and provide proof-of-concept evidence that stalling CDK9 signaling may enable successful targeted combination therapy in TNBC. Therefore, the specific objective is to assess the pharmacological response of dual EGFR-CDK9 targeting in TNBC patient-derived xenograft (PDX) mouse models in vivo. We envisage that this PoC project will translate our identified successful synergistic treatment into an effective future novel and safe combinatorial targeting strategy benefiting TNBC patients.", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["767854"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)", "FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)"], "EU_Contribution": ["EUR 1 499 812,50"], "Project_Title": ["Hypermutated tumors: insight into genome maintenance and cancer vulnerabilities provided by an extreme burden of somatic mutations"], "Total_Cost": ["EUR 1 499 812,50"], "Country": ["Spain", "Spain"], "Project_ACR": ["HYPER-INSIGHT"], "Technology_Description": "Mutations are the fuel of any evolutionary process, and this also applies to carcinogenesis. The advent of affordable DNA sequencing has enabled mutagenic processes in the human soma to be quantified genome-wide, revealing a striking occurrence of hypermutated tumors. They exhibit an extreme load of somatic changes, often harbouring hundreds of single-nucleotide variants and/or indels per megabase. The HYPER-INSIGHT project is organized into three objectives, which aim to take advantage of the unique opportunity provided by genome sequences of hypermutated and ultramutated tumors. In particular, this work planned in this project aims to further our knowledge on (i) the regional organization of the DNA replication and repair program in human cells, and the determinants thereof, (ii) the extent of selection which acts on somatic variants in various pathways or complexes and (iii) opportunities for selectively targeting DNA repair deficiencies that manifest as hypermutation. Methodologically, our work will employ a three-pronged approach. First, we will perform a multitude of rigorous statistical analyses that draw on the rich and still-expanding resources provided by cancer genomics consortia. Second, we will perform exome and genome sequencing, focusing on ultramutated tumors caused by specific defects in the DNA maintenance machinery. Third, the project involves conditional essentiality screens on cancer cell lines with hypermutant backgrounds. Their goal is to discover synthetic lethality relationships, useful for targeting hypermutating cells, while sparing healthy ones. In summary, one of the promises of cancer genome sequencing projects was to elucidate the mechanisms underlying mutational processes in the human soma, advancing our understanding of this important facet of cancer biology. We will work towards realizing this promise, thereby strengthening the EU\u2019s position in the global scientific endeavour.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-02-01"], "Project_ID": ["757700"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITE D'AIX MARSEILLE", "UNIVERSITE D'AIX MARSEILLE"], "EU_Contribution": ["EUR 1 859 656"], "Project_Title": ["Horn and Crescent. Connections, Mobility and Exchange between the Horn of Africa and the Middle East in the Middle Ages"], "Total_Cost": ["EUR 1 859 656"], "Country": ["France", "France"], "Project_ACR": ["HORNEAST"], "Technology_Description": "This project offers the first comprehensive study of medieval connections between the Horn of Africa and the Middle East in both Christian and Islamic contexts. It pursues the hypothesis that mobility and exchange along trade and pilgrimage routes, on both sides of and across the Red Sea, were not only vectors for the spread of Islam but also factors of African Christianities\u2019 resiliency and reconfiguration at the same time. Medieval connections of Ethiopian and Nubian Christianities with other Eastern Christian churches have longer been studied than has been the spread of Islam across the Red Sea or along the Nile valley which remains poorly known. These parallel connections within Christen- and Islamdom across the same area have never been studied jointly, nor have been Christian-Muslim relations on such a scale. The project ultimately aims to reconnect the Horn of Africa to the global history of the area by connecting disjoint fields of research.", "To": ["2022-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["726206"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["CHALMERS TEKNISKA HOEGSKOLA AB", "CHALMERS TEKNISKA HOEGSKOLA AB", "OMNISYS INSTRUMENTS AB"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["TeraHertz quasiOptical Receiver"], "Total_Cost": ["EUR 150 000"], "Country": ["Sweden", "Sweden", "Sweden"], "Project_ACR": ["THOR"], "Technology_Description": "Remote sensing and monitoring in various environments solves many scientific and societal problems. Examples are: industrial air pollution control, global atmosphere surveillance, our planet system and the universe exploration, process controls in industry, and material research in laboratories. Molecular absorption/emission feature, combined with a high penetration depth of THz waves through dust, short wavelength allowing for high pointing directivity, all these factors determine the uniqueness of the THz range of electro-magnetic wave spectrum (0.1-10THz) in the mentioned applications. High radiometric sensitivity of THz wave detectors is a vital selection criterion for a THz system to become attractive. Uncooled THz detectors/mixers show adequate sensitivity only for frequencies below 1THz, whereas \u201csupra-THz\u201d (>1THz) detectors require cooling down to 4K. This limitation hinders exploitation of THz spectroscopy for such important application as atmosphere monitoring, local and global pollution surveillance, security, as well as universal sciences, in full. Small-scale satellites, balloons, portable sensors, can\u2019t afford LHe cooling or power thirsty 4K cryo-coolers. For large-scale space missions, 4K cooling has already been utilized (e.g. Herschel and Planck Space observatories, COBE, etc), however it limited the missions lifetime significantly. ", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-11-01"], "Project_ID": ["780170"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 1 496 687"], "Project_Title": ["Algorithmic Verification of String Manipulating Programs"], "Total_Cost": ["EUR 1 496 687"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["AV-SMP"], "Technology_Description": "String is among the most fundamental and commonly used data types in virtually all modern programming languages, especially with the rapidly growing popularity of scripting languages (e.g. JavaScript and Python). Programs written in such languages tend to perform heavy string manipulations, which are complex to reason about and could easily lead to programming mistakes. In some cases, such mistakes could have serious consequences, e.g., in the case of client-side web applications, cross-site scripting (XSS) attacks that could lead to a security breach by a malicious user.", "To": ["2022-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["759969"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI TRENTO", "UNIVERSITA DEGLI STUDI DI TRENTO"], "EU_Contribution": ["EUR 1 491 479"], "Project_Title": ["Accurate and Scalable Processing of Big Data in Earth Observation"], "Total_Cost": ["EUR 1 491 479"], "Country": ["Italy", "Italy"], "Project_ACR": ["BigEarth"], "Technology_Description": "During the last decade, a huge number of earth observation (EO) satellites with optical and Synthetic Aperture Radar sensors onboard have been launched and advances in satellite systems have increased the amount, variety and spatial/spectral resolution of EO data. This has led to massive EO data archives with huge amount of remote sensing (RS) images, from which mining and retrieving useful information are challenging. In view of that, content based image retrieval (CBIR) has attracted great attention in the RS community. However, existing RS CBIR systems have limitations on: i) characterization of high-level semantic content and spectral information present in RS images, and ii) large-scale RS CBIR problems since their search mechanism is time-demanding and not scalable in operational applications. The BigEarth project aims to develop highly innovative feature extraction and content based retrieval methods and tools for RS images, which can significantly improve the state-of-the-art both in the theory and in the tools currently available. To this end, very important scientific and practical problems will be addressed by focusing on the main challenges of Big EO data on RS image characterization, indexing and search from massive archives. In particular, novel methods and tools will be developed, aiming to: 1) characterize and exploit high level semantic content and spectral information present in RS images; 2) extract features directly from the compressed RS images; 3) achieve accurate and scalable RS image indexing and retrieval; and 4) integrate feature representations of different RS image sources into a unified form of feature representation. Moreover, a benchmark archive with high amount of multi-source RS images will be constructed. From an application point of view, the developed methodologies and tools will have a significant impact on many EO data applications, such as accurate and scalable retrieval of: specific man-made structures and burned forest areas.", "To": ["2023-03-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-04-01"], "Project_ID": ["759764"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 439 893"], "Project_Title": ["Ant navigation: how complex behaviours emerge from mini-brains in interaction with their natural habitats"], "Total_Cost": ["EUR 1 439 893"], "Country": ["France", "France"], "Project_ACR": ["EMERG-ANT"], "Technology_Description": "Navigation is one of the most crucial and most challenging problems animals face. Behavioural analyses have shown that animals make use of a number of different mechanisms to navigate, but very little is known of how spatial information is processed and integrated by the brain. This project will exploit the stunning ability of ants in learning long visual routes to investigate the mechanisms of navigation in a brain numerically much simpler than vertebrate. We will combine an ecological approach with state-of-the-art technologies to enable a thorough control of sensory-motor cues while the ant is navigating in virtual-reality reconstructions of its natural environments. This new and powerful method will enable us to dissect the mechanisms underlying the emergence of navigational behaviours by performing straightforward manipulations. The results will be modelled in the light of insect neurobiology and integrated into an increasingly complete neural architecture. This neural architecture will be embedded into an agent navigating in the same virtual-reality environment as the real ants for testing. The advantage of such an inter-disciplinary approach is that failures of our agent will help us identify gaps in our knowledge and thus fuel new experimentation. Reciprocally, our agent will become increasingly refined in the light of incoming experimental results. This will create a positive feedback towards a complete, multi-level understanding of navigation in the wild. The findings will inspire new robust solutions for navigational problems that can be applied to bio-robotics.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["759817"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["FUNDACIO PRIVADA INSTITUT CATALA D'INVESTIGACIO QUIMICA", "AICURIS ANTI-INFECTIVE CURES GMBH"], "EU_Contribution": ["EUR 743 618,88"], "Project_Title": ["Enabling Technologies and Drug Discovery: Continuous Flow Processes to Discover Novel Antiviral Inhibitors"], "Total_Cost": ["EUR 743 618,88"], "Country": ["Spain", "Germany"], "Project_ACR": ["VIRO-FLOW"], "Technology_Description": "VIRO-FLOW project aims to integrate the advantages of continuous flow chemistry with in vitro microfluidic bioassay technologies for the fast and efficient discovery of novel and innovative inhibitors of the Hepatitis B Virus (HBV). This programme aims to contribute to the development of innovative methodologies that allow more efficient production of new compounds with anti-viral activity, specifically against HBV, for future transfer of technology and knowledge between different sectors with relevant economic impact. The global objective of this ITN-EID programme is to provide an innovative and high-level training in drug discovery and enabling technologies for 3 Early-Stage Researchers (ESRs), supported by a network of experts in anti-infective therapeutics, specifically virology and bacteriology in AiCuris, a pharmaceutical company; and the Institute of Chemical Research of Catalonia (ICIQ), a research Institute focused on sustainable chemistry in the field of catalysis and flow chemistry (through its technology development unit ERTFLOW). This ITN will educate the next generation of well-prepared ESRs, providing them with the skills necessary to pursue successful careers in a rapidly emerging field that requires novel multidisciplinary technological development as well as it will also be the channel for educating well-trained researchers with the scientific, technical and entrepreneurial skills so highly needed in the drug discovery field.", "To": ["2021-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-11-01"], "Project_ID": ["766058"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["BEN-GURION UNIVERSITY OF THE NEGEV", "BEN-GURION UNIVERSITY OF THE NEGEV"], "EU_Contribution": ["EUR 1 328 712"], "Project_Title": ["Engineering translation machinery to produce light-responsive protein-polymers"], "Total_Cost": ["EUR 1 328 712"], "Country": ["Israel", "Israel"], "Project_ACR": ["PolControl"], "Technology_Description": "A general and versatile technology to engineer visible light-responsive biological agents will enable spatio-temporal manipulation and interrogation of proteins, pathways, and cells, and the design of \u201csmart\u201d biomaterials that can direct and respond to biological processes on-demand. Site specific incorporation of multiple visible-light-responsive chemical groups at the polypeptide level will constitute a universal methodology for precise production of light-responsive proteins and protein-based materials. However, inadequate engineering of the protein translation apparatus limits the number and complexity of chemical groups that can be incorporated into proteins as synthetic amino acids (sAAs). This limitation precludes the incorporation of recently discovered visible-light-responsive chemical groups, hinders protein engineering efforts, and excludes production of biomaterials in which multiple identical sAAs provide new physical or biophysical properties. We propose to overcome this challenge by generating a genomic-engineering based platform for co-evolution of multiple components of the translation machinery (the aminoacyl tRNA synthetase, tRNA, and elongation factor) to select for cellular machinery capable of multi-site incorporation of highly substituted azobenzenes with a range of biologically relevant photochemical properties. We will then utilize these translation systems to produce libraries of azobenzene-containing protein-based materials to elucidate the sequence-function requirements for directing light-responsive self-assembly of macromolecular structures, and to generate biomaterial formulations for control of various intra- and extra-cellular processes. By developing and marrying technologies in synthetic biology, chemistry, and biomaterials, this study will enable the synthesis of light-responsive proteins, deepen our understanding of natural and evolved translation systems, and create new classes of functional light-responsive biomaterials.", "To": ["2022-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["756996"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA", "UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA"], "EU_Contribution": ["EUR 1 494 662"], "Project_Title": ["How natural hand usage shapes behavior and intrinsic and task-evoked brain activity."], "Total_Cost": ["EUR 1 494 662"], "Country": ["Italy", "Italy"], "Project_ACR": ["HANDmade"], "Technology_Description": "A seminal concept in modern neuroscience is the plasticity of the developing and adult brain that underpins the organismic ability to adapt to the ever-changing environment and internal states. Conversely, recent studies indicate that ongoing sensory input seems not crucial to modulate the overall level of brain activity, which instead it is strongly determined by its intrinsic fluctuations. These observations raise a fundamental question: what is coded in the intrinsic activity? This project tests the hypothesis that intrinsic activity represents and maintains an internal model of the environment built through the integration of information from visual and bodily inputs. The bodily inputs represent the physical and functional interaction that our body establishes with the external environment. In this framework, the hand has a special role, as it represents the primary means of interaction with the environment. ", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["759651"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["CHALMERS TEKNISKA HOEGSKOLA AB", "CHALMERS TEKNISKA HOEGSKOLA AB"], "EU_Contribution": ["EUR 1 499 085"], "Project_Title": ["Strong interactions for precision nuclear physics"], "Total_Cost": ["EUR 1 499 085"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["PrecisionNuclei"], "Technology_Description": "Nuclear physics is a cornerstone in our scientific endeavour to understand the universe. Indeed, atomic nuclei bring us closer to study both the stellar explosions in the macrocosmos, where the elements are formed, and the fundamental symmetries of the microcosmos. Having access to a a precise description of the interactions between protons and neutrons would provide a key to new knowledge across 20 orders of magnitude; from neutrinos to neutron stars. Despite a century of the finest efforts, a systematic description of strongly interacting matter at low energies is still lacking. Successful theoretical approaches, such as mean-field and shell models, rely on uncontrolled approximations that severely limit their predictive power in regions where the model has not been adjusted.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["758027"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITY OF GLASGOW", "UNIVERSITY OF GLASGOW"], "EU_Contribution": ["EUR 1 490 050"], "Project_Title": ["Computing the Face Syntax of Social Communication"], "Total_Cost": ["EUR 1 490 050"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["FACESYNTAX"], "Technology_Description": "Social interactions are critical to all societies. One of the most powerful tools for social interaction is the face \u2013 a complex system comprising variations of movement (expressions), morphology (shape/structure) and complexion (color/texture). Consequently, the face can elicit myriad rapid social judgments (e.g. personality, emotion, group membership, age, health, social status) with significant consequences (e.g. sentencing/voting decisions, social isolation, job offers). Yet, little is known about how the complex, dynamic face transmits the myriad messages that regulate social interactions in different cultures, how these complex face signals map onto psychological processes (e.g. categorical/dimensional perception) or which signals facilitate or hinder cross-culture communication. This is largely due to fragmented research on social concepts (mental states, personality, emotions), face signals (morphology, movements, complexion) and culture, which, consequently, has overlooked a possible latent algebraic, syntactical structure to social face signals across cultures. My own work hints at such a structure. My ambitious program will unify these fragments to derive the first generative, algebraic and syntactical model of social face signals using innovative methods combining social/cultural psychology, 3D dynamic computer graphics, vision science psychophysical methods, and mathematical psychology. It will thus test and validate a new theoretical framework of social face signals that will unite both categorical/dimensional and universal/culture-specific accounts of social face perception. This framework is highly relevant in the context of globalization and cultural integration where social communication using virtual agents is integral to modern society. It is thus imperative to equip digital agents with the tools to flexibly generate socially and culturally sophisticated face signals. FACESYNTAX will thus transfer the generative model to social robotics.", "To": ["2023-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["759796"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITY OF BRISTOL", "UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 952 561"], "Project_Title": ["Soft Water: understanding what makes a fluid behave like water"], "Total_Cost": ["EUR 952 561"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["SOFTWATER"], "Technology_Description": "Water is the most common and yet least understood material on Earth. Despite its simplicity, the structure of the water molecule is responsible for a vast array of properties that are unlike those of other fluids. Water anomalies, like the density maximum at 4 degrees Celsius, play a fundamental role in determining the Earth's climate, and ultimately the very existence of life. From an anthropic viewpoint, the properties of water are as if they were fine-tuned. It is this uniqueness that hinders our understanding of how water behaves in many natural systems and technological applications; for example, our inability to predict the stability limit of water in supercooled clouds, and the rates of ice crystallization, is credited as being one of the biggest unknowns in models of Climate Change, where the scattering of energy from suspended ice droplets in the clouds plays a central role in determining Earth's radiation budget.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["759187"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["ACADEMISCH ZIEKENHUIS LEIDEN", "ACADEMISCH ZIEKENHUIS LEIDEN"], "EU_Contribution": ["EUR 1 499 850"], "Project_Title": ["Protein nano-patterning using DNA nanotechnology; control of surface-based immune system activation"], "Total_Cost": ["EUR 1 499 850"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["BioNanoPattern"], "Technology_Description": "Protein nanopatterning concerns the geometric arrangement of individual proteins with nanometre accuracy. It is becoming apparent that protein nanopatterns are essential for cellular function, and have roles in cell signalling and protection, phagocytosis and stem cell differentiation. Recent research indicates that our immune system is activated by nanopatterned antibody platforms, which initiate the classical Complement pathway by binding to the first component of Complement, the C1 complex. DNA nanotechnology can be used to form self-assembled nanoscale structures, which are ideal for use as templates to pattern proteins with specific geometries and nanometre accuracy. I propose to use DNA to nanopattern antigens and agonistic aptamers with defined geometry to study and control Complement pathway activation by the C1 complex.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["759517"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI PADOVA", "UNIVERSITA DEGLI STUDI DI PADOVA"], "EU_Contribution": ["EUR 1 446 250"], "Project_Title": ["Microbioreactor platforms as in vivo-like systems to probe the role of Neuroblastoma-derived Exosomes in cancer dissemination"], "Total_Cost": ["EUR 1 446 250"], "Country": ["Italy", "Italy"], "Project_ACR": ["MICRONEX"], "Technology_Description": "Engineers can actively contribute to fields thought to be out of their \u201ccomfort zones\u201d. We can be leaders of discoveries that translate into advances in the understanding of disease and improving human health. Engineers might use different language and tools than Life Sciences Scientists but we find a common ground, as the laws of Thermodynamics, Physics, and Mathematics also apply to biological phenomena.", "To": ["2022-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["759467"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["POLITECHNIKA POZNANSKA", "POLITECHNIKA POZNANSKA"], "EU_Contribution": ["EUR 1 385 000"], "Project_Title": ["'If immortality unveil\u2026'\u2013 development of the novel types of energy storage systems with excellent long-term performance"], "Total_Cost": ["EUR 1 385 000"], "Country": ["Poland", "Poland"], "Project_ACR": ["IMMOCAP"], "Technology_Description": "The major goal of the project is to develop a novel type of an electrochemical capacitor with high specific power (up to 5 kW/kg) and energy (up to 20 Wh/kg) preserved along at least 50 000 cycles. Thus, completion of the project will result in remarkable enhancement of specific energy, power and life time of modern electrochemical capacitors. Advanced electrochemical testing (galvanostatic cycling with constant power loads, electrochemical impedance spectroscopy, accelerated aging and kinetic tests) will be accompanied by materials design and detailed characterization. Moreover, the project aims at the implementation of novel concepts of the electrolytes and designing of new operando technique for capacitor characterization. All these efforts aim at the development of sustainable and efficient energy conversion and storage system.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Poland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["759603"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["FUNDACIO CENTRE DE REGULACIO GENOMICA", "FUNDACIO CENTRE DE REGULACIO GENOMICA"], "EU_Contribution": ["EUR 1 381 286"], "Project_Title": ["Understanding the Balbiani body: A super-organelle linked to dormancy in oocytes"], "Total_Cost": ["EUR 1 381 286"], "Country": ["Spain", "Spain"], "Project_ACR": ["DORMANTOOCYTE"], "Technology_Description": "Female germ cells, oocytes, are highly specialised cells. They ensure the continuity of species by providing the female genome and mitochondria along with most of the nutrients and housekeeping machinery the early embryo needs after fertilisation. Oocytes are remarkable in their ability to survive for long periods of time, up to 50 years in humans, and retain the ability to give rise to a young organism while other cells age and die. Surprisingly little is known about oocyte dormancy. A key feature of dormant oocytes of virtually all vertebrates is the presence of a Balbiani body, which is a non-membrane bound compartment that contains most of the organelles in dormant oocytes and disappears as the oocyte matures. ", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-03-01"], "Project_ID": ["759107"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["HELMHOLTZ ZENTRUM POTSDAM DEUTSCHESGEOFORSCHUNGSZENTRUM GFZ", "HELMHOLTZ ZENTRUM POTSDAM DEUTSCHESGEOFORSCHUNGSZENTRUM GFZ"], "EU_Contribution": ["EUR 1 499 308"], "Project_Title": ["Climate Sensitivity of Glacial Landscape Dynamics"], "Total_Cost": ["EUR 1 499 308"], "Country": ["Germany", "Germany"], "Project_ACR": ["COLD"], "Technology_Description": "How do erosion rates in glacial landscapes vary with climate change and how do such changes affect the dynamics of mountain glaciers? Providing quantitative constraints towards this question is the main objective of COLD. These constraints are so important because mountain glaciers are sensitive to climate change and their deposits provide a unique history of Earths terrestrial climate that allows reconstructing leads and lags in the climate system.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["759639"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["TECHNISCHE UNIVERSITAET MUENCHEN", "TECHNISCHE UNIVERSITAET MUENCHEN"], "EU_Contribution": ["EUR 1 366 875"], "Project_Title": ["Demystifying the Quark-Gluon Plasma"], "Total_Cost": ["EUR 1 366 875"], "Country": ["Germany", "Germany"], "Project_ACR": ["QGP-MYSTERY"], "Technology_Description": "The primary objective of this project is to explore the properties of a new state of matter, the Quark-Gluon Plasma (QGP), at the highest energies to date. The QGP consists of asymptotically free quarks and gluons and the evidence for its discovery was announced in experiments analyzing collisions of heavy ions. Previous experiments at lower energies have caused a dramatic change of paradigm in our understanding - measurements at Relativistic Heavy Ion Collider showed that the QGP behaves like a strongly coupled liquid, instead of the weakly interacting gas expected by theorists. The focus of this project is the measurement of the anisotropic flow, which has proven to be the most informative probe for studying the properties of nuclear matter produced in heavy-ion collisions. The analysis methods to be utilized are multiparticle correlation techniques developed by the PI. Currently mainly the first moments (averages) of multiparticle correlations are used. Within the scope of the theoretical subproject we aim to derive analytic expressions for higher order moments of multiparticle correlations by continuing a pioneering work recently initiated by the PI. The here proposed project aims also the measurement of new flow observables, so-called Symmetric Cumulants, recently introduced in the field by PI. The recent restart of Large Hadron Collider at top energy, a record breaking 5.02 TeV center of mass energy, offers a truly unique and a timely opportunity for this project. The main dataset will comprise the heavy-ion collisions collected with ALICE detector at the Large Hadron Collider. Collisions of smaller systems will be scrutinized as well in order to determine the onset of QGP formation. This project offers a unique opportunity to pin down quantitatively the properties of the QGP, beyond the rather qualitative analyses that are currently carried out in the field. It also will impact the fields of high energy physics, nuclear physics, cosmology and hydrodynamics.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["759257"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["TECHNISCHE UNIVERSITEIT DELFT", "TECHNISCHE UNIVERSITEIT DELFT"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Constructing polar rotors in metal-organic frameworks for memories and energy harvesting"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["MemoMOFEnergy"], "Technology_Description": "I seek to develop new ferroelectrics based on metal-organic frameworks with dipolar rotors. Ferroelectrics are targeted to be used as physically flexible memories and mechanical energy harvesters for biocompatible sensors and implantable monitoring devices. ", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["759212"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN", "STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Topological phononics through nano-optomechanical interactions"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["TOPP"], "Technology_Description": "The concept of topology has proven very powerful in predicting and explaining a range of intriguing phenomena for the behaviour of electrons in solid-state materials, including the existence of topological phases that offer robust transport with unusual characteristics. This program aims to create and study topological behaviour for sound in systems that couple light and mechanical motion through radiation pressure. I will realize on-chip nano-optomechanical systems where many optical and mechanical modes interact. Through this interaction, suitable laser illumination will induce phononic transport with properties that are not found in any natural material. In particular, they will establish topologically nontrivial acoustic phases that we will create and explore in space and time using a new optical measurement technique. The induced behaviour crucially depends on the extreme coupling between optical fields and nanomechanical resonators when both are confined at the nanoscale. I aim to study three manifestations of topological behaviour: (1) The creation of an acoustic quantum Hall phase, in which topologically protected unidirectional sound propagation should emerge, in edge modes that are robust against disorder. (2) The formation of a new type of topological insulator arising from optomechanical nonlinearity, supporting topological acoustic solitons with unusual dynamics. (3) The breaking of parity-time symmetry in mechanical systems that undergo both optical damping and amplification, a phase transition with unique topological properties.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["759644"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["BAYERISCHE JULIUS-MAXIMILIANS UNIVERSITAT WURZBURG", "BAYERISCHE JULIUS-MAXIMILIANS UNIVERSITAT WURZBURG"], "EU_Contribution": ["EUR 1 497 905"], "Project_Title": ["Targeting the Oncogenic Function of Myc in vivo"], "Total_Cost": ["EUR 1 497 905"], "Country": ["Germany", "Germany"], "Project_ACR": ["TarMyc"], "Technology_Description": "The transcription factor Myc plays a central role in tumourigenesis but was deemed undruggable due to it being an essential protein. However, recent proof-of-principle studies in mice using a dominant negative allele of Myc demonstrated the dependency of established tumours on Myc function and showed that mice tolerated Myc inhibition to a degree that allowed tumour regression. In line with these observations my group found Myc to regulate distinct sets of genes at low, physiological and high, oncogenic levels, because promoters differ in their affinity for Myc. This notion implies the compelling possibility to specifically target the oncogenic functions of Myc.", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["759139"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITY OF BRISTOL", "UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 1 712 581"], "Project_Title": ["Stimulated Brillouin Scattering based RF to Optical Signal Transduction and Amplification"], "Total_Cost": ["EUR 1 712 581"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["SBS3-5"], "Technology_Description": "While the detection of weak signals (down to the single photon level) in the optical frequency range is routine on account of the high photon energy (compared to thermal excitation energy kBT) and the availability of efficient detectors, this is not the case in the radio frequency (RF) and microwave frequency regimes wherein thermal (Johnson) noise in detectors swamps out the faint RF signals (in applications from radio astronomy, MRI to radar) and requires the use of cryogenic amplifiers. The ability to map signals efficiently from the microwave to optical regime becomes paramount for distant systems to communicate with each other using low loss telecom fibers. Both classical (radio over fiber systems) and quantum (linking two superconducting qubit processors in two dilution fridges) information processing systems will benefit greatly from the development of an efficient RF to optical signal transducer.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["758843"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITE DE NAMUR ASBL", "UNIVERSITE DE NAMUR ASBL"], "EU_Contribution": ["EUR 1 499 313"], "Project_Title": ["Women in Africa"], "Total_Cost": ["EUR 1 499 313"], "Country": ["Belgium", "Belgium"], "Project_ACR": ["AfricanWomen"], "Technology_Description": "Rates of domestic violence and the relative risk of premature death for women are higher in sub-Saharan Africa than in any other region. Yet we know remarkably little about the economic forces, incentives and constraints that drive discrimination against women in this region, making it hard to identify policy levers to address the problem. This project will help fill this gap. ", "To": ["2023-07-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-08-01"], "Project_ID": ["759294"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 498 368"], "Project_Title": ["The Graeco-Egyptian State: Hellenistic Archives from Egyptian Mummies"], "Total_Cost": ["EUR 1 498 368"], "Country": ["France", "France"], "Project_ACR": ["GESHAEM"], "Technology_Description": "The aim of GESHAEM is to investigate economy, fiscality and territorial management in the most important agricultural region of Egypt, the Fayyum, in the first century of the Greek domination (3rd century BCE). For this purpose, a large corpus of administrative and fiscal papyri discovered in Egyptian mummies will be studied: the unpublished Greek and Egyptian papyri of the Jouguet collection of the Sorbonne. Coming from bilingual archives, these documents will change our view of the early Ptolemaic kingdom in the third century BCE. The history of this Hellenistic kingdom has long been described as the history of a Greek kingdom. Recently, however, the native Egyptian contribution in the building of this kingdom has come to the fore: the Ptolemaic administration was in large part made up of people of Egyptian origin who spoke and wrote both Greek and Egyptian, continuing a millennia-old administrative tradition adapted to the new regime. The Jouguet papyri open new perspectives because, unlike most demotic documents of the Graeco-Roman period, these were not written inside temples but for the civil government. Like the Greek ones they are concerned with the agricultural administration of the Fayyum region. The Jouguet texts were written on second-hand papyrus reused to make mummy casing called cartonnage. Most of these decorated mummy cartonnages were destroyed immediately after their discovery at the beginning of the 20th century, but around twenty remain in part of the Jouguet collection that has not yet been inventoried. The extraction of new papyri from the remaining cartonnages will be achieved without destroying the objects themselves, which will be restored and, for the first time, studied in their own right. Thus GESHAEM intends to bring new data both for historians working on the ancient economy and fiscality, as well as for art historians.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-02-01"], "Project_ID": ["758907"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["BILKENT UNIVERSITESI VAKIF", "BILKENT UNIVERSITESI VAKIF"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Resonant Electromagnetic Microscopy: Imaging Cells Electronically"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Turkey", "Turkey"], "Project_ACR": ["REM"], "Technology_Description": "Microfluidics technology has been quite successful in fabricating small, low-cost devices with excellent analyte handling capabilities. However, the main detection paradigm in microfluidics has still been optical microscopy \u2014 which is a bulky and expensive technique. A chip-scale detection scheme that can provide multidimensional information is much needed for the widespread adoption of lab-on-a-chip technology. So far, successful capacitive and resonant electrical sensors have been deployed in the field; yet the focus of these sensors has been to obtain the electrical volume or location of a particle \u2014 which constitutes only a limited piece of information about the analytes. Here we propose to redesign and utilize resonant electrical sensors in a radically different way to obtain images of cells in a microfluidic channel. The technique proposed can also multiplex on-chip cytometry greatly, accomplish low-cost and high-throughput single-cell transit-time characterization, obtain not only the electrical but also the geometrical size of analytes, determine the dielectric permittivity of analytes, in addition to capturing 1D profile or 2D images of cells. At the basic science level, the project will enhance our understanding of the interaction of electromagnetic fields and living matter at the single cell level and may provide new insights on cell motility, growth and mechanics.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Turkey"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["758769"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON", "UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Deciphering super-Earths using Artificial Intelligence"], "Total_Cost": ["EUR 1 500 000"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["ExoAI"], "Technology_Description": "The discovery of extrasolar planets - i.e. planets orbiting other stars - has fundamentally transformed our understanding of planets, solar systems and our place in the Milky Way. Recent discoveries have shown that planets between 1-2 R are the most abundant in our galaxy, so called super-Earths. Yet, they are entirely absent from our own solar system. Their nature, chemistry, formation histories or climate remain very much a mystery. Estimates of their densities suggest a variety of possible planet types and formation/evolution scenarios but current degeneracies cannot be broken with mass/radius measures alone. Spectroscopy of their atmospheres can provide vital insight. Recently, the first atmosphere around a super-Earth, 55 Cnc e, was discovered, showcasing that these worlds are far more complex than simple densities allow us to constrain. ", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["758892"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITATEA POLITEHNICA DIN BUCURESTI", "UNIVERSITATEA POLITEHNICA DIN BUCURESTI"], "EU_Contribution": ["EUR 1 325 000"], "Project_Title": ["Provably Correct Networks"], "Total_Cost": ["EUR 1 325 000"], "Country": ["Romania", "Romania"], "Project_ACR": ["CORNET"], "Technology_Description": "Networks are the backbone of our society, but configuring them is error-prone and tedious: misconfigured networks result in headline grabbing network outages that affect many users and hurt company revenues while security breaches that endanger millions of customers. There are currently no guarantees that deployed networks correctly implement their operator\u2019s policy.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Romania"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["758815"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["ECOLE POLYTECHNIQUE", "ECOLE POLYTECHNIQUE"], "EU_Contribution": ["EUR 1 499 845"], "Project_Title": ["Exploring Relations in Structured Data with Functional Maps"], "Total_Cost": ["EUR 1 499 845"], "Country": ["France", "France"], "Project_ACR": ["EXPROTEA"], "Technology_Description": "We propose to lay the theoretical foundations and design efficient computational methods for analyzing, quantifying and exploring relations and variability in structured data sets, such as collections of geometric shapes, point clouds, and large networks or graphs, among others. Unlike existing methods that are tied and often limited to the underlying data representation, our goal is to design a unified framework in which variability can be processed in a way that is largely agnostic to the underlying data type. ", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["758800"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITE LYON 1 CLAUDE BERNARD", "UNIVERSITE LYON 1 CLAUDE BERNARD"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Quantum optomechanics at ROOm Temperature"], "Total_Cost": ["EUR 1 500 000"], "Country": ["France", "France"], "Project_ACR": ["Q-ROOT"], "Technology_Description": "5 years ago, the field of optomechanics has entered the quantum regime. By doing so, this domain which investigates the reciprocal interactions between light and mechanical motion has overcome the long-standing paradox of Quantum Mechanical effects at the macroscopic scale. Such outstanding achievement relies on the so-called \u201ccavity nano-optomechanical\u201d technology, which combines strongly reduced dimensions with ultra-high optical confinement, enabling very large optomechanical coupling rates at the nanoscale.", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["758794"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 497 996"], "Project_Title": ["Innovative Strategies for Unprecedented Remote C-H bond Functionalization by Catalysis"], "Total_Cost": ["EUR 1 497 996"], "Country": ["France", "France"], "Project_ACR": ["FarCatCH"], "Technology_Description": "Over the last years, the landscape of the organic chemistry has been reshaped with impressive advances made in the transition metal-catalyzed carbon-hydrogen (C-H) bond functionalization field. Indeed, the functionalization of building blocks that do not display a reactive functional group but only a simple C-H bond is attractive as it avoids time-consuming and expensive prefunctionalization steps and limits the generation of waste. However, as energies required to break C-H bonds are similar, the differentiation between two C-H bonds and the selective functionalization of only one of them remain a key challenge. Therefore, the available approaches are still unsatisfactory due to important limitations: low reactivity, limited scopes and selectivity issues. In this proposal, a general approach to functionalize a CH bond located at a Far position (from a functional group) by Catalysis (FarCatCH) will be implemented with a special focus on underexplored transformations, affording important sulfur-and fluorine-containing compounds. Herein, I will develop new synthetic approaches for the remote functionalization of molecules based on i) a substrate-selectivity control and ii) the design of new catalysts using supramolecular tools. I will then iii) address a longstanding reactivity issue in organic synthesis: the trifluoromethylation of aliphatic compounds and apply the supramolecular catalysts for a remote enantioselective transformation.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["758710"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["OSLO UNIVERSITETSSYKEHUS HF", "OSLO UNIVERSITETSSYKEHUS HF"], "EU_Contribution": ["EUR 1 499 638"], "Project_Title": ["Imaging Perfusion Restrictions from Extracellular Solid Stress"], "Total_Cost": ["EUR 1 499 638"], "Country": ["Norway", "Norway"], "Project_ACR": ["ImPRESS"], "Technology_Description": "Even the perfect cancer drug must reach its target to have an effect. The ImPRESS project main objective is to develop a novel imaging paradigm coined Restricted Perfusion Imaging (RPI) to reveal - for the first time in humans - vascular restrictions in solid cancers caused by mechanical solid stress, and use RPI to demonstrate that alleviating this force will repair the cancerous microenvironment and improve therapeutic response. Delivery of anti-cancer drugs to the tumor is critically dependent on a functional vascular bed. Developing biomarkers that can measure how mechanical forces in a solid tumor impair perfusion and promotes therapy resistance is essential for treatment of disease. ", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["758657"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 056 664"], "Project_Title": ["Correlated frontiers of many-body quantum mathematics and condensed matter physics"], "Total_Cost": ["EUR 1 056 664"], "Country": ["France", "France"], "Project_ACR": ["CORFRONMAT"], "Technology_Description": "One of the main challenges in condensed matter physics is to understand strongly correlated quantum systems. Our purpose is to approach this issue from the point of view of rigorous mathematical analysis. The goals are twofold: develop a mathematical framework applicable to physically relevant scenarii, take inspiration from the physics to introduce new topics in mathematics. The scope of the proposal thus goes from physically oriented questions (theoretical description and modelization of physical systems) to analytical ones (rigorous derivation and analysis of reduced models) in several cases where strong correlations play the key role.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["758620"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE"], "EU_Contribution": ["EUR 1 785 195"], "Project_Title": ["Nanostructured catalyst overcoats for renewable chemical production from biomass"], "Total_Cost": ["EUR 1 785 195"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["CATACOAT"], "Technology_Description": "In the CATACOAT project, we will develop layer-by-layer solution-processed catalyst overcoating methods, which will result in catalysts that have both targeted and broad impacts. We will produce highly active, stable and selective catalysts for the upgrading of lignin \u2013 the largest natural source of aromatic chemicals \u2013 into commodity chemicals, which will have an important targeted impact. The broader impact of our work will lie in the production of catalytic materials with unprecedented control over the active site architecture.", "To": ["2022-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["758653"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI TRENTO", "UNIVERSITA DEGLI STUDI DI TRENTO"], "EU_Contribution": ["EUR 1 339 351"], "Project_Title": ["VAriable ResolutIon Algorithms for macroMOLecular Simulation"], "Total_Cost": ["EUR 1 339 351"], "Country": ["Italy", "Italy"], "Project_ACR": ["VARIAMOLS"], "Technology_Description": "Within the broad spectrum of biological soft matter systems, large proteins and protein assemblies occupy a central role. These molecules are extremely versatile: they can catalyze chemical reactions, transport atoms and molecules across the cellular membrane, bind to foreign bodies to be destroyed, or combine into large molecular machines that perform a variety of different tasks. One of the most prominent problems in the computational study of these macromolecules is that the cost of using accurate atomistic models dramatically increases with system size. Simplified, coarse-grained representations offer an elegant and effective alternative to high-resolution models, and enable the simulation of large systems over extended time scales; the other side of the coin, however, is that the missing chemical detail often represents an insurmountable limitation to the realistic reproduction of the properties of interest. The main goal of the VARIAMOLS project is to develop and apply novel computer-aided methods for the study of large molecular assemblies and their dynamics, thus bridging the existing gap between computational cost and chemical accuracy. Specifically, the research will unfold along two intertwined lines: 1) the development of non-uniform resolution models of the system, which optimize the balance between detail and efficiency; and 2) the study of dynamics-mediated properties of protein assemblies. The working philosophy of VARIAMOLS has two complementary and strictly interconnected aspects: on the one hand, the theoretical and algorithmic advancement of the methods currently employed to represent and simulate biomolecules; on the other hand, the systematic application of the developed methods to real-life case studies of great relevance for medical science and technology, with a particular focus on viruses and antibodies.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["758588"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITEIT LEIDEN", "UNIVERSITEIT LEIDEN"], "EU_Contribution": ["EUR 1 847 500"], "Project_Title": ["Visualizing melting magnetic order and spin fluctuations in the cuprates"], "Total_Cost": ["EUR 1 847 500"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["SpinMelt"], "Technology_Description": "The aim of this proposal is to bring new insight and understanding into the remarkable phase diagram of the cuprates, representing the larger family of unconventional superconductors, by visualizing the process of melting magnetic order and the resulting spin fluctuations (magnons) on the atomic scale.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["758572"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["FUNDACIO INSTITUT DE CIENCIES FOTONIQUES", "FUNDACIO INSTITUT DE CIENCIES FOTONIQUES"], "EU_Contribution": ["EUR 1 789 165"], "Project_Title": ["Probing nanoscale and femtosecond fluctuations in high temperature superconductors"], "Total_Cost": ["EUR 1 789 165"], "Country": ["Spain", "Spain"], "Project_ACR": ["SeeSuper"], "Technology_Description": "One of the major outstanding challenges in condensed matter physics is the origin of high temperature superconductivity. Low temperature BCS superconductivity is mediated by the electron-phonon interaction, but this interaction is believed to be too weak to explain high temperature superconductivity. Instead electron interactions are considered responsible, but experimental proof has been difficult to obtain. Despite over thirty years of research, the mechanism responsible for generating the superconducting state still remains unknown. ", "To": ["2022-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-11-01"], "Project_ID": ["758461"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITEIT LEIDEN", "UNIVERSITEIT LEIDEN"], "EU_Contribution": ["EUR 1 499 956"], "Project_Title": ["From colloidal joints to reconfigurable matter"], "Total_Cost": ["EUR 1 499 956"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["RECONFMATTER"], "Technology_Description": "Self-assembly of colloidal particles has emerged as the most promising strategy to obtain fundamental insights into otherwise prohibitively complex systems as well as to create new functional materials from the bottom up. However, most self-assembled colloidal structures are static and thus limited in their functionality. ", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["758383"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["THE UNIVERSITY OF SUSSEX", "THE UNIVERSITY OF SUSSEX"], "EU_Contribution": ["EUR 1 488 763"], "Project_Title": ["Genomic basis of convergent evolution in the Trinidadian Guppy"], "Total_Cost": ["EUR 1 488 763"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["GUPPYCon"], "Technology_Description": "Many species have independently evolved similar phenotypes in response to similar environmental challenges. This phenomenon, termed convergent evolution, reflects both the power and the limits of adaptation. However, we often do not know at what scale evolution has repeated itself: did selection act on the same genes in different populations or species, or did convergence result from selection on different genes? This is because, until recently, it has not been possible to investigate the genomic basis of evolution in most systems, limiting our understanding of the factors that facilitate or inhibit convergence and adaptation. To fully understand convergent evolution we need to query the genomic response to selection and determine genotype-phenotype links in systems where convergent adaptation is well established. The Trinidadian guppy (Poecilia reticulata) is a system that offers the opportunity to test the roles of multiple factors in convergent evolution: this species includes multiple natural and experimentally established populations that have repeatedly evolved similar phenotypes under similar predation environments. I propose to fully characterize the genomic-basis of repeated adaptive evolution in guppies. Aim 1 will identify regions that repeatedly show signatures of selection, and will contrast the nature of selection in natural and experimental populations that differ in age and levels of founding genetic diversity. Aim 2 will identify genomic regions associated with phenotypes that are known to play a significant role in local adaptation in the guppy using quantitative genetics approaches. I will then directly test the effects of candidate genes using novel functional genomic approaches, as detailed in Aim 3. Overall, this project will test whether repeated selection led to convergence at the genomic level, determine the genetic basis of convergent adaptations, and ultimately understand how convergent evolution has occurred in an important wild system.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["758382"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE"], "EU_Contribution": ["EUR 1 293 023"], "Project_Title": ["Universality and chaos in PT-symmetric quantum systems"], "Total_Cost": ["EUR 1 293 023"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["CHAOS-PIQUANT"], "Technology_Description": "The world of our daily experiences, described by classical physics, is built out of fundamental particles, governed by the laws of quantum mechanics. The striking difference between quantum and classical behaviour becomes most apparent in the realm of chaos, an extreme sensitivity to initial conditions, which is common in classical systems but impossible under quantum laws. The investigation of characteristic features of quantum systems whose classical counterparts are chaotic has illuminated foundational problems and led to a variety of technological applications. Traditional quantum theory focuses on the description of closed systems without losses. Every realistic system, however, contains unwanted losses and dissipation, but the idea to engineer them to generate desirable effects has recently come into the focus of scientific attention. The surprising properties of quantum systems with balanced gain and loss (PT-symmetric systems) have sparked much interest. The first experiments on PT-symmetry in optics have been identified as one of the top ten physics discoveries of the past decade in Nature Physics. New experimental areas are rapidly emerging. Our understanding of PT-symmetric quantum systems, however, is still limited. One major shortcoming is that the emergence of chaos and universality in these systems is hitherto nearly unexplored. I propose to investigate PT-symmetric quantum chaos to establish this new research area and overturn some common perceptions in the existing fields of PT-symmetry and quantum chaos. Ultimately this will lead to new experimental applications and quantum technologies. Building on recent conceptual breakthroughs I have made, I will a) identify spectral and dynamical features of chaos in PT-symmetric quantum systems, b) establish new universality classes, c) provide powerful semiclassical tools for the simulation of generic quantum systems, and d) facilitate experimental applications in microwave cavities and cold atoms.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["758453"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITY OF DURHAM", "UNIVERSITY OF DURHAM", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 1 444 980"], "Project_Title": ["THE AFTERMATH OF THE EAST ASIAN WAR OF 1592-1598."], "Total_Cost": ["EUR 1 444 980"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom"], "Project_ACR": ["Aftermath"], "Technology_Description": "Aftermath seeks to understand the legacy of the East Asian War of 1592-1598. This conflict involved over 500,000 combatants from Japan, China, and Korea; up to 100,000 Korean civilians were abducted to Japan. The war caused momentous demographic upheaval and widespread destruction, but also had long-lasting cultural impact as a result of the removal to Japan of Korean technology and skilled labourers. The conflict and its aftermath bear striking parallels to events in East Asia during World War 2, and memories of the 16th century war remain deeply resonant in the region. However, the war and its immediate aftermath are also significant because they occurred at the juncture of periods often characterized as \u201cmedieval\u201d and \u201cearly modern\u201d in the East Asian case. What were the implications for the social, economic, and cultural contours of early modern East Asia? What can this conflict tell us about war \u201caftermath\u201d across historical periods and about such periodization itself? There is little Western scholarship on the war and few studies in any language cross linguistic, disciplinary, and national boundaries to achieve a regional perspective that reflects the interconnected history of East Asia. Aftermath will radically alter our understanding of the region\u2019s history by providing the first analysis of the state of East Asia as a result of the war. The focus will be on the period up to the middle of the 17th century, but not precluding ongoing effects. The team, with expertise covering Japan, Korea, and China, will investigate three themes: the movement of people and demographic change, the impact on the natural environment, and technological diffusion. The project will be the first large scale investigation to use Japanese, Korean, and Chinese sources to understand the war\u2019s aftermath. It will broaden understandings of the early modern world, and push the boundaries of war legacy studies by exploring the meanings of \u201caftermath\u201d in the early modern East Asian context.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["758347"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI PADOVA", "UNIVERSITA DEGLI STUDI DI PADOVA"], "EU_Contribution": ["EUR 1 452 210"], "Project_Title": ["Republics on the Stage of Kings. Representing Republican State Power in the Europe of Absolute Monarchies (late 16th - early 18th century)"], "Total_Cost": ["EUR 1 452 210"], "Country": ["Italy", "Italy"], "Project_ACR": ["RISK"], "Technology_Description": "RISK investigates Republican pageantry and encomiastic production from late 16th- to early 18th-century Europe, with regard to the Italian city-states that maintained their independence throughout this timeframe (Venice, Genoa, Lucca), the Republic of Ragusa (today in southernmost Croatia) and the Dutch Republic. A multidisciplinary corpus of sources is taken into account, including: praising texts celebrating Republican values; paintings and engravings displaying civic rituals, or portraying mythological prosopopoeias of the Republic; and written accounts of public ceremonies, such as the election of the Doge or the triumph performed after a victorious campaign.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["758450"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 499 375"], "Project_Title": ["Discourse reporting in African storytelling"], "Total_Cost": ["EUR 1 499 375"], "Country": ["France", "France"], "Project_ACR": ["SPEECHREPORTING"], "Technology_Description": "The project explores the role of discourse reporting in West African storytelling and the grammatical strategies used by storytellers to achieve their goals. It focuses on three phenomena characteristic of the narrative grammar of a number of West African languages: ", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-02-01"], "Project_ID": ["758232"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 293 763"], "Project_Title": ["Analysis of Geometrical Effects on Dispersive Equations"], "Total_Cost": ["EUR 1 293 763"], "Country": ["France", "France"], "Project_ACR": ["ANADEL"], "Technology_Description": "We are concerned with localization properties of solutions to hyperbolic PDEs, especially problems with a geometric component: how do boundaries and heterogeneous media influence spreading and concentration of solutions. While our first focus is on wave and Schr\u00f6dinger equations on manifolds with boundary, strong connections exist with phase space localization for (clusters of) eigenfunctions, which are of independent interest. Motivations come from nonlinear dispersive models (in physically relevant settings), properties of eigenfunctions in quantum chaos (related to both physics of optic fiber design as well as number theoretic questions), or harmonic analysis on manifolds.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-02-01"], "Project_ID": ["757996"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON", "UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 1 499 998"], "Project_Title": ["Design of Mixed Anion Inorganic Semiconductors for Energy Conversion"], "Total_Cost": ["EUR 1 499 998"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["DISCOVER"], "Technology_Description": "Multi-component systems offer the chemical and structural flexibility necessary to meet the needs of next-generation energy conversion. The vast majority of work in the field has focused on mixed-metal compounds. DISCOVER will computationally explore mixed-anion compounds. These are complex systems that provide significant technical challenges for atomistic and electronic structure modelling. Currently, structure-property relationships are poorly developed and there is a distinct lack of understanding of order-disorder transitions. Crucially, no systematic approach has been established for designing new combinations which can be tailored to match the criteria for technological applications. ", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["758345"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Lipid asymmetry: a cellular battery?"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["ASYMMEM"], "Technology_Description": "It is a basic textbook notion that the plasma membranes of virtually all organisms display an asymmetric lipid distribution between inner and outer leaflets far removed from thermodynamic equilibrium. As a fundamental biological principle, lipid asymmetry has been linked to numerous cellular processes. However, a clear mechanistic justification for the continued existence of lipid asymmetry throughout evolution has yet to be established. We propose here that lipid asymmetry serves as a store of potential energy that is used to fuel energy-intense membrane remodelling and signalling events for instance during membrane fusion and fission. This implies that rapid, local changes of trans-membrane lipid distribution rather than a continuously maintained out-of-equilibrium situation are crucial for cellular function. Consequently, new methods for quantifying the kinetics of lipid trans-bilayer movement are required, as traditional approaches are mostly suited for analysing quasi-steady-state conditions. Addressing this need, we will develop and employ novel photochemical lipid probes and lipid biosensors to quantify localized trans-bilayer lipid movement. We will use these tools for identifying yet unknown protein components of the lipid asymmetry regulating machinery and analyse their function with regard to membrane dynamics and signalling in cell motility. Focussing on cell motility enables targeted chemical and genetic perturbations while monitoring lipid dynamics on timescales and in membrane structures that are well suited for light microscopy. Ultimately, we aim to reconstitute lipid asymmetry as a driving force for membrane remodelling in vitro. We expect that our work will break new ground in explaining one of the least understood features of the plasma membrane and pave the way for a new, dynamic membrane model. Since the plasma membrane serves as the major signalling hub, this will have impact in almost every area of the life sciences.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2018-01-01"], "Project_ID": ["758334"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 499 750"], "Project_Title": ["Spatio-temporal Organization and Expression of the Genome"], "Total_Cost": ["EUR 1 499 750"], "Country": ["France", "France"], "Project_ACR": ["4D-GenEx"], "Technology_Description": "This project investigates the two-way relationship between spatio-temporal genome organization and coordinated gene regulation, through an approach at the interface between physics, computer science and biology.", "To": ["2023-03-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-04-01"], "Project_ID": ["757956"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITE CATHOLIQUE DE LOUVAIN", "UNIVERSITE CATHOLIQUE DE LOUVAIN"], "EU_Contribution": ["EUR 1 998 125"], "Project_Title": ["Deciphering virus-host interactions using correlated confocal-atomic force microscopy"], "Total_Cost": ["EUR 1 998 125"], "Country": ["Belgium", "Belgium"], "Project_ACR": ["NanoVirus"], "Technology_Description": "Viruses are a major class of pathogens that infect a variety of organisms. Infection is a multistep process that involves the concerted action of both virus and host cell machineries. The first steps of virus infection include cell binding, cell entry and release of the viral genetic material. Entry pathways are largely defined by the preliminary interactions between viruses and their receptors at the cell surface. Those interactions determine the mechanisms of virus attachment, uptake, and, ultimately, penetration into the cytosol. Elucidating the complex interplay between viruses and their receptors at the cell surface is an essential step towards establishing a full picture of the infection process. ", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["758224"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 618 125"], "Project_Title": ["Unveiling Planet Formation by Observations and Simulations"], "Total_Cost": ["EUR 1 618 125"], "Country": ["Germany", "Germany"], "Project_ACR": ["UFOS"], "Technology_Description": "With each newly detected exoplanet system, the planet formation theory is constantly gaining weight in the astrophysical research. The planets origin is a mystery which can only be solved by understanding the protoplanetary disks evolution. Recent disk observations by the new class of interferometer telescopes are challenging the existing theory of planet formation. They reveal astonishing detailed structures of spirals and rings in the dust emission which have never been seen before. Those structures are often claimed to be caused by embedded planets, which is difficult to explain with current models. This growing discrepancy between observation and theory forces us to realize: a novel disk modeling is essential to move on. Separate gas or dust evolution models have reached their limit and the gap between those has to be closed.", "To": ["2023-05-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2018-06-01"], "Project_ID": ["757957"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 1 498 013"], "Project_Title": ["Past and Present Musical Encounters across the Strait of Gibraltar"], "Total_Cost": ["EUR 1 498 013"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom"], "Project_ACR": ["MESG"], "Technology_Description": "MESG explores how the notion of a collective European-North African cultural memory has been articulated through music for different sociopolitical ends in colonial and postcolonial contexts. Based on the notion of convivencia (the alleged coexistence between Christians, Jews and Muslims in Islamic Spain), music has been employed as a means of social control and representation during French-Spanish colonialism in North Africa (1912\u201356) and as a model for multiculturalism among North African communities in Europe today. Current scholarship on musical exchange between Europe and North Africa is fragmented, often focusing on isolated geographical case studies. There is limited understanding of how a collective cultural memory has shaped musical practice and discourse in the colonial past and the postcolonial present. In contrast, MESG offers a comparative study of music and colonialism in the Maghreb. By examining colonial music scholarship, policy and education, and musical encounters between different cultural groups, MESG probes the social dynamics of musical interaction at this time, framed by issues of race, imperialism and cultural memory. Second, MESG explores how the idea of a collective cultural memory is invoked through musical collaboration today, by focusing on various genres such as Arab-Andalusian music and flamenco. Rather than separating these historical periods, however, MESG analyses how modern-day practices of musical exchange in the region are shaped by discourses and networks formed during colonialism. Musical exchange will be read against the wider context of multiculturalism, immigration and cultural diplomacy that underpins postcolonial relations between Europe and North Africa. Combining archival and ethnographic research, this groundbreaking project brings together for the first time different geographical, linguistic and musical specialisms, leading towards a fuller understanding of musical exchange in the region.", "To": ["2023-03-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-04-01"], "Project_ID": ["758221"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION", "FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Molecular and structural mechanisms for metazoan replication origin specification"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["ORISPECIFICATION"], "Technology_Description": "Cellular life depends on the timely and accurate duplication of chromosomal DNA through semi-conservative replication to sustain genomic integrity and organismal viability. In all domains of life, DNA replication relies on dedicated initiator proteins that recognize and bind specific genomic sites, termed replication origins, to facilitate the loading of ring-shaped replicative helicases onto DNA. While origin recognition by initiators is determined by specific DNA sequences in prokaryotes and in the eukaryote S. cerevisiae, origin specification in higher eukaryotes instead appears to rely on chromatin context and DNA structure. Yet, how initiators help specify replication origins at the molecular level and how their binding sites are established in higher eukaryotes remain foremost and long-standing questions in the field. This research proposal focuses on uncovering the molecular and structural principles for chromosomal binding site selection by the eukaryotic initiator, the origin recognition complex (ORC), in metazoan systems. Employing integrated biochemical, structural, and cell-based approaches, we aim to 1) elucidate how ORC binds DNA and how DNA structural elements contribute to this interaction, 2) determine how nucleosomes are recognized by ORC, and 3) identify auxiliary binding partners of ORC and establish how they contribute to origin specification. The outcomes of our proposed efforts will have far-reaching implications for multiple scientific fields by defining mechanistic links between chromatin architecture and DNA replication initiation, and they will set the foundation to understand at the molecular level how the replication initiation program is altered during cell differentiation and development. Our studies also have significant biomedical relevance, as failure to precisely replicate chromosomal DNA leads to genetic instability, which in turn underpins many human diseases, including cancer and certain developmental disorders.", "To": ["2023-06-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-07-01"], "Project_ID": ["757909"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["WEIZMANN INSTITUTE OF SCIENCE", "WEIZMANN INSTITUTE OF SCIENCE"], "EU_Contribution": ["EUR 1 494 000"], "Project_Title": ["Deciphering the computations underlying visual processing:Repurposing of retinal cells and how they are decoded by the visual thalamus"], "Total_Cost": ["EUR 1 494 000"], "Country": ["Israel", "Israel"], "Project_ACR": ["RetinalRepurposing"], "Technology_Description": "Visual processing begins in the retina, with ~30 types of retinal ganglion cells (RGCs), each encodes a specific visual modality, such as edges or motion. A major challenge for deciphering the visual code is mapping the connections between each RGC and its target neurons, such as in the lateral geniculate nucleus (LGN) and, via the LGN, the visual cortex. Recently, this challenge became even greater, as we and others revealed that the modality encoded by RGCs\u2014traditionally considered a fixed hardwired property of each RGC type\u2014can be altered. Direction selective RGCs reorient their directional tuning following visual adaptation, and other RGCs change their polarity preference (On/Off) as light level changes. These newly discovered dramatic changes in the core computations of RGCs depart from the known retinal adaptation which results in gain adjustments but no modality changes. We term them repurposing.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["757732"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["WEIZMANN INSTITUTE OF SCIENCE", "WEIZMANN INSTITUTE OF SCIENCE"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Malaria Parasite Networking: Discovering Modes of Cell-Cell Communication"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Israel", "Israel"], "Project_ACR": ["MalPar.NET"], "Technology_Description": "Malaria, caused by Plasmodium falciparum, is a devastating parasitic disease effecting hundreds of millions of people worldwide. The parasite\u2019s transmission cycle between humans and mosquitoes involves a remarkable series of morphological transformations. While it is clear that, for such a complex journey, the parasites must develop means to sense their host and coordinate their actions; these modes of communication remain one of the greatest mysteries in malaria biology. In fact, since an individual parasite is enclosed by three membranes inside its human host, the red blood cell (RBC), they were not thought to possess any communication ability. However, we discovered that these parasites, despite the multiple barriers, are able to communicate and exchange episomal genes by releasing exosome-like vesicles, thereby opening the exciting new field of malaria parasite communication. Our initial data demonstrate that these vesicles serve as a secure tool for the delivery of remarkable components. ", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["757743"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["THE UNIVERSITY OF EDINBURGH", "THE UNIVERSITY OF EDINBURGH"], "EU_Contribution": ["EUR 1 499 981"], "Project_Title": ["Search for new physics through lattice simulations"], "Total_Cost": ["EUR 1 499 981"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["NewPhysLat"], "Technology_Description": "Despite its monumental success, we have reason to think that the Standard Model of particle physics is an effective description of a more fundamental theory. In order to maximise the chances of success of experiments to pinpoint the breakdown of this theory, it is crucial to provide precise, ab-initio theoretical predictions to compare it with. One of the main challenges in producing these predictions is to reliably take account of the non-perturbative, confining phase of the strong interaction. So far, the most efficient way to achieve that is to use numerical lattice simulations. In this proposal, I focus on theoretical quantities involved in the search for new physics and propose an ambitious lattice simulation programme to determine them precisely. Firstly, I propose to predict rare kaon decays amplitudes. These decays are extremely rare in the Standard Model and are expected to be sensitive to new physics. Secondly, I propose to determine how to include isospin breaking effects in the calculation of the anomalous magnetic moment of the muon and meson leptonic and semi-leptonic decay rates. Including these effects is a highly non-trivial task which is necessary to push the theoretical precision of these observables beyond the percent level in order to provide a higher constraint on the Standard Model. Thirdly, I propose to explore holographic cosmology, an ambitious and innovative alternative to \u039bCDM, the \"standard model\" of cosmology. Finally, all these projects will directly contribute to the development of Grid, the emerging world-leading software solution for lattice simulations. All these projects are strongly pushing the boundaries of the application of lattice simulations and the results will be confronted with experimental measurements within the next five years. This proposal focuses on supporting world-leading particle physics experiments and I will deliver high-impact results which have the potential to uncover new physics beyond the Standard Model.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["757646"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["HELSINGIN YLIOPISTO", "HELSINGIN YLIOPISTO"], "EU_Contribution": ["EUR 1 908 652"], "Project_Title": ["From processes to modelling of methane emissions from trees"], "Total_Cost": ["EUR 1 908 652"], "Country": ["Finland", "Finland"], "Project_ACR": ["MEMETRE"], "Technology_Description": "Atmospheric concentration of the strong greenhouse gas methane (CH4) is rising with an increased annual growth rate. Biosphere has an important role in the global CH4 budget, but high uncertainties remain in the strength of its different sink and source components. Among the natural sources, the contribution of vegetation to the global CH4 budget is the least well understood. Role of trees to the CH4 budget of forest ecosystems has long been overlooked due to the perception that trees do not play a role in the CH4 dynamics. Methanogenic Archaea were long considered as the sole CH4 producing organisms, while new findings of aerobic CH4 production in terrestrial vegetation and in fungi show our incomplete understanding of the CH4 cycling processes. Enclosure measurements from trees reveal that trees can emit CH4 and may substantially contribute to the net CH4 exchange of forests.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["757695"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["THE UNIVERSITY OF EDINBURGH", "THE UNIVERSITY OF EDINBURGH", "UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 1 425 440"], "Project_Title": ["Syntax shaped by cognition: transforming theories of syntactic systems through laboratory experiments"], "Total_Cost": ["EUR 1 425 440"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom"], "Project_ACR": ["SYNCOG"], "Technology_Description": "Human language is incredibly diverse: languages differ at all levels of linguistic structure from phonetics to syntax. But behind these differences there are intriguing similarities, patterns that reappear across many languages, and others that rarely crop up. A foundational goal of linguistics is to distil a set of principles explaining the shared features of our languages by appealing to properties of the human cognitive and linguistic system. While many such principles have been formulated, throughout the history of the field, little direct behavioural evidence has been offered for them. Indeed, the connection between common features of language systems and cognition is controversial in the broader community of scientists studying language from different perspectives. Longstanding debates center around whether such constraints exist, what features of cognition they might reflect, and if they are specific to language.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["757643"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UPPSALA UNIVERSITET", "UPPSALA UNIVERSITET"], "EU_Contribution": ["EUR 1 121 660"], "Project_Title": ["New mechanisms and materials for odd-frequency superconductivity"], "Total_Cost": ["EUR 1 121 660"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["ODDSUPER"], "Technology_Description": "Odd-frequency superconductivity is a very unique superconducting state that is odd in time or, equivalently, frequency, which is opposite to the ordinary behavior of superconductivity. It has been realized to be the absolute key to understand the surprising physics of superconductor-ferromagnet (SF) structures and has also enabled the whole emerging field of superconducting spintronics. This project will discover and explore entirely new mechanisms and materials for odd-frequency superconductivity, to both generate a much deeper understanding of superconductivity and open for entirely new functionalities. Importantly, it will generalize and apply my initial discoveries of two new odd-frequency mechanisms, present in bulk multiband superconductors and in hybrid structures between topological insulators and conventional superconductors, respectively. In both cases odd-frequency superconductivity is generated without any need for ferromagnets or interfaces, completely different from the situation in SF structures. The result will be a significant expansion of the concept and importance of odd-frequency superconductivity to a very wide class of materials, ranging from multiband, bilayer, and nanoscale superconductors to topological superconductors. The project will also establish the connection between topology and odd-frequency pairing, which needs to be addressed in order to understand topological superconductors, as well as incorporate new materials and functionality into traditional SF structures. To achieve these goals the project will develop a novel methodological framework for large-scale and fully quantum mechanical studies with atomic level resolution, solving self-consistently for the superconducting state and incorporating quantum transport calculations.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["757553"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["FREIE UNIVERSITAET BERLIN", "FREIE UNIVERSITAET BERLIN"], "EU_Contribution": ["EUR 1 486 800"], "Project_Title": ["Complexity Inside NP - A Computational Geometry Perspective"], "Total_Cost": ["EUR 1 486 800"], "Country": ["Germany", "Germany"], "Project_ACR": ["CGinsideNP"], "Technology_Description": "Traditional complexity theory focuses on the dichotomy between P and NP-hard problems. Lately, it has become increasingly clear that this misses a major part of the picture. Results by the PI and others offer glimpses on a fascinating structure hiding inside NP: new computational problems that seem to lie between polynomial and NP-hard have been identified; new conditional lower bounds for problems with large polynomial running times have been found; long-held beliefs on the difficulty of problems in P have been overturned. Computational geometry plays a major role in these developments, providing some of the main questions and concepts.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["757609"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["THE UNIVERSITY OF EDINBURGH", "THE UNIVERSITY OF EDINBURGH"], "EU_Contribution": ["EUR 1 497 755"], "Project_Title": ["Modelling the genomic landscapes of selection and speciation"], "Total_Cost": ["EUR 1 497 755"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["ModelGenomLand"], "Technology_Description": "Understanding how natural selection, random genetic drift and demographic events interact to generate and maintain genetic and species diversity has been the central focus of population genetics for many decades. We now have the necessary genome sequence data to make detailed and powerful inferences about the evolutionary past of populations and species, yet our ability to meaningfully interpret such data has remained fundamentally limited.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["757648"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 499 640"], "Project_Title": ["Organic Functionalisation of N2 Using Metal-Main Group and Metal-Metal Cooperativity"], "Total_Cost": ["EUR 1 499 640"], "Country": ["France", "France"], "Project_ACR": ["OrFuNCo"], "Technology_Description": "Activation and transformation of dinitrogen (N2) into other nitrogen-containing compounds is a challenge for chemists due to the inertness of this molecule. The well-established Haber-Bosch process allows transformation of dinitrogen into ammonia (NH3) at the industrial scale through heterogeneous catalysis, but it is an energy-demanding process (1-2% of the World's annual energy consumption). The ammonia thus produced is almost totally converted into more value-added chemicals. Similarly, in Nature, the nitrogenase enzymes are able to convert N2 into NH3 catalytically, spending a high amount of energy to produce a molecule which is subsequently transformed into amino-acids or nucleotides. At a time where energy savings have become a major issue, alternatives to the Haber-Bosch process are desirable. Improving ammonia synthesis still prevails in current dinitrogen chemistry, despite the relative lack of utility of this molecule. Conversely, a catalytic process affording a nitrogen-containing product directly from N2 does not exist yet, and remains a highly attractive, though challenging, goal. Given this context, the PI proposes to investigate novel molecular chemical tools capable of direct conversion of N2 into nitrogen-containing organic compounds under mild conditions, while approaching the catalysis problem from a new direction. Two unprecedented strategies relying on the symbiotic reactivity of two partners towards dinitrogen will be detailed herein. In the first one, metal-boron frustrated Lewis pairs (FLPs) will help activate and functionalise N2, thus unlocking the thus far missing FLP chemistry of this small molecule. In the second one, it is proposed to explore the virgin territory of N2's cycloaddition reactivity, thanks to bimetallic cooperativity. By the careful examination of stoichiometric reactions considered as key steps of putative catalytic cycles, tackling the \"Holy Grail\" of catalysis will be facilitated.", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-03-01"], "Project_ID": ["757501"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 499 756"], "Project_Title": ["Rag-independent regulation of mTOR by Amino Acids"], "Total_Cost": ["EUR 1 499 756"], "Country": ["Germany", "Germany"], "Project_ACR": ["noRAG-TOR"], "Technology_Description": "The mTOR complex 1 (mTORC1) is a master regulator of cell growth and metabolism in response to environmental cues, such as nutrients. Its dysregulation is a common feature of several life-threatening disorders, including cancer and metabolic disease. Therefore, understanding how mTORC1 is regulated is of great importance for both basic and translational research.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2018-02-01"], "Project_ID": ["757729"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE"], "EU_Contribution": ["EUR 1 499 292"], "Project_Title": ["Next Generation Machine Intelligence for Medical Image Representation and Analysis"], "Total_Cost": ["EUR 1 499 292"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["MIRA"], "Technology_Description": "Machines capable of analysing and interpreting medical scans with super-human performance would transform healthcare as much as medical imaging itself did over the last century. With an increasing complexity and volume of data the interpretation of images and extraction of clinically useful information push human abilities to the limit. There is high risk that critical patterns of disease go undetected. We require powerful and trustworthy computational tools based on machine intelligence to support experts and go beyond human performance to tackle the major challenges in clinical practice. Two key ingredients are currently missing: 1) interpretable statistical representations that capture important information while reducing complexity; 2) intelligent algorithms that leverage knowledge across multiple tasks to solve the most challenging problems such as early detection of pathology.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["757173"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 497 031"], "Project_Title": ["ABIOtic Synthesis of RNA: an investigation on how life started before biology existed"], "Total_Cost": ["EUR 1 497 031"], "Country": ["France", "France"], "Project_ACR": ["ABIOS"], "Technology_Description": "The emergence of life is one of the most fascinating and yet largely unsolved questions in the natural sciences, and thus a significant challenge for scientists from many disciplines. There is growing evidence that ribonucleic acid (RNA) polymers, which are capable of genetic information storage and self-catalysis, were involved in the early forms of life. But despite recent progress, RNA synthesis without biological machineries is very challenging. The current project aims at understanding how to synthesize RNA in abiotic conditions. I will solve problems associated with three critical aspects of RNA formation that I will rationalize at a molecular level: (i) accumulation of precursors, (ii) formation of a chemical bond between RNA monomers, and (iii) tolerance for alternative backbone sugars or linkages. Because I will study problems ranging from the formation of chemical bonds up to the stability of large biopolymers, I propose an original computational multi-scale approach combining techniques that range from quantum calculations to large-scale all-atom simulations, employed together with efficient enhanced-sampling algorithms, forcefield improvement, cutting-edge analysis methods and model development. ", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-02-01"], "Project_ID": ["757111"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA", "UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA"], "EU_Contribution": ["EUR 1 337 480,94"], "Project_Title": ["Unveiling the dark universe with gravitational waves: Black holes and compact stars as laboratories for fundamental physics"], "Total_Cost": ["EUR 1 337 480,94"], "Country": ["Italy", "Italy"], "Project_ACR": ["DarkGRA"], "Technology_Description": "In recent years, our theoretical understanding of the strong-field regime of gravity has grown in parallel with the observational confirmations that culminated in the landmark detection of gravitational waves (GWs). This synergy of breakthroughs at the observational, technical, and conceptual level offers the unprecedented opportunity to merge traditionally disjoint areas, and to make strong gravity a precision tool to probe fundamental physics. ", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["757480"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 937 000"], "Project_Title": ["Artificial cell-cell interactions for light switchable cell organization and signaling"], "Total_Cost": ["EUR 1 937 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["ARTIST"], "Technology_Description": "The bottom-up assembly of tissue from cellular building blocks constitutes a promising, yet highly challenging approach to engineer complex tissues. The challenge lies in controlling cell-cell interactions, which determine how cells organize with respect to each other, how they work together and consequently whether such a multicellular architecture will be functional. The limited spatial and temporal control over cell-cell interactions current biological and chemical approaches provide severely restricts bottom-up tissue engineering. Here, I propose a new way to control cell-cell interactions. I aim to regulate cell-cell interactions with visible light using proteins that reversibly homo- or heterodimerize under blue or red light. These photoswitchable cell-cell interactions provide sustainable, non-invasive, dynamic and reversible control over cell-cell interactions with unprecedented spatial and temporal resolution. First of all, we will focus on various light dependent protein interactions to mediate cell-cell contacts. The detailed characterization (strength, dynamics, interaction modes and orthogonality) of these new photoswitchable cell-cell interactions will provide the framework for the bottom-up construction of tissue-like structures. Secondly, we will use these photoswitchable cell-cell interactions to assemble cells into multicellular architectures with predictable and programmable organization. The dynamic and reversible nature of the photoswitchable contacts will allow us to locally alter interactions at any point in time, to rearrange and obtain asymmetric multicellular structures, which are typical of tissues. Finally, we will also explore how the photoswitchable cell-cell interactions alter cell behavior and signaling. Ultimately, this will pave the way for the bottom-up assembly of multicellular architectures, enabling us to control precisely and dynamically their organization in space and time as well as regulate how cells work together.", "To": ["2023-06-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2018-07-01"], "Project_ID": ["757593"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM", "ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM"], "EU_Contribution": ["EUR 1 498 544"], "Project_Title": ["Dissecting the cellular and molecular dynamics of bone marrow fibrosis for improved diagnostics and treatment"], "Total_Cost": ["EUR 1 498 544"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["deFIBER"], "Technology_Description": "Bone marrow (BM) fibrosis is the continuous replacement of blood forming cells in the bone marrow by scar tissue, ultimately leading to failure of the body to produce blood cells. Primary myelofibrosis (PMF), an incurable blood cancer, is the prototypic example of the step-wise development of BM fibrosis. The specific mechanisms that cause BM fibrosis are not understood, in particular as the cells driving fibrosis have remained obscure.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["757339"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["FORSCHUNGSZENTRUM JULICH GMBH", "FORSCHUNGSZENTRUM JULICH GMBH"], "EU_Contribution": ["EUR 1 465 944"], "Project_Title": ["Controlled Mechanical Manipulation of Molecules"], "Total_Cost": ["EUR 1 465 944"], "Country": ["Germany", "Germany"], "Project_ACR": ["CM3"], "Technology_Description": "The idea to freely control the atomic-scale structure of matter has intrigued scientists for many decades. The low-temperature scanning probe microscope (LT SPM) has become the instrument of choice for this task since it allows the rearrangement of atoms and molecules on a surface. There is, however, no generic SPM-based method for the manipulation of molecules beyond lateral rearrangement. The goal of this project is to develop controlled mechanical manipulation of molecules (CM3) in which a LT SPM is used to handle large organic molecules in three dimensions with optimal control over position, orientation and shape. CM3 will become a game-changing technique for research on molecular properties and molecular-scale engineering, because it combines fully deterministic manipulation with broad access to molecular degrees of freedom for the first time. In CM3 the tip is attached to a single reactive atom within a molecule. Tip displacement guides the molecule into a desired conformation while the surface provides a second (weaker) fixation. The fundamental challenge addressed by this project is the identification of precise molecular conformations at any time during manipulation. The solution is a big data approach where large batches of automatically recorded SPM manipulation data are structured using machine learning and interpreted by comparison to atomistic simulations. The key idea is a comparison of entire conformation spaces at once, which is robust, even if the theory is not fully quantitative. The obtained map of the conformation space is used to determine molecular conformations during manipulation by methods of control theory. The effectiveness of this approach will be demonstrated in experiments that unambiguously reveal the structure-conductance relation for a series of molecules and that realize the engineering paradigm of piecewise assembly on the molecular scale by constructing a direct current rotor / motor from individual components.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["757634"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET", "KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 1 499 952"], "Project_Title": ["Pervasive Upstream Non-Coding Transcription Underpinning Adaptation"], "Total_Cost": ["EUR 1 499 952"], "Country": ["Denmark", "Denmark"], "Project_ACR": ["PUNCTUATION"], "Technology_Description": "Genomic DNA represents the blueprint of life: it instructs solutions to challenges during life cycles of organisms. Curiously DNA in higher organisms is mostly non-protein coding (e.g. 97% in human). The popular \u201cjunk-DNA\u201d hypothesis postulates that this non-coding DNA is non-functional. However, high-throughput transcriptomics indicates that this may be an over-simplification as most non-coding DNA is transcribed. This pervasive transcription yields two molecular events that may be functional: 1.) resulting long non-coding RNA (lncRNA) molecules, and 2.) the act of pervasive transcription itself. Whereas lncRNA sequences and functions differ on a case-by-case basis, RNA polymerase II (Pol II) transcribes most lncRNA. Pol II activity leaves molecular marks that specify transcription stages. The profiles of stage-specific activities instruct separation and fidelity of transcription units (genomic punctuation). Pervasive transcription affects genomic punctuation: upstream lncRNA transcription over gene promoters can repress downstream gene expression, also referred to as tandem Transcriptional Interference (tTI). Even though tTI was first reported decades ago a systematic characterization of tTI is lacking. Guided by my expertise in lncRNA transcription I recently identified the genetic material to dissect tTI in plants as an independent group leader. My planned research promises to reveal the genetic architecture and the molecular hallmarks defining tTI in higher organisms. Environmental lncRNA transcription variability may trigger tTI to promote organismal responses to changing conditions. We will address the roles of tTI in plant cold response to test this hypothesis. I anticipate our findings to inform on the fraction of pervasive transcription engaging in tTI. My proposal promises to advance our understanding of genomes by reconciling how the transcription of variable non-coding DNA sequences can elicit equivalent functions.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["757411"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI TORINO", "UNIVERSITA DEGLI STUDI DI TORINO"], "EU_Contribution": ["EUR 1 051 590"], "Project_Title": ["New Models of Sanctity in Italy (1960s-2010s).A Semiotic Analysis of Norms, Causes of Saints, Hagiography, and Narratives"], "Total_Cost": ["EUR 1 051 590"], "Country": ["Italy", "Italy"], "Project_ACR": ["NeMoSanctI"], "Technology_Description": "In cultures with a strong Catholic tradition saints represent models of life perfection, dialectically elaborated by a plurality of subjects and expressed in a thick intertextual network. Since the Second Vatican Council (1962-1965), when the Church promoted a policy of adaptation of her tradition to the modern world, the modeling of sanctity has undergone a deep transformation. In a context of global change, new models of sanctity have assumed a central role in guiding the faithful by proposing a renewed religious alternative to growing secularization.", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["757314"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 1 759 732,50"], "Project_Title": ["HYbrid PERovskites for Next GeneratION Solar Cells and Lighting"], "Total_Cost": ["EUR 1 759 732,50"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["HYPERION"], "Technology_Description": "An emerging class of materials called hybrid perovskites is poised to revolutionise how power is both produced and consumed by enabling the production of highly-efficient, tunable solar photovoltaics (PV) and light-emitting diodes (LEDs) at exceptionally low cost. Although the efficiencies of perovskite devices are rising fast, both PV and LEDs fall short of out-performing current technology and reaching their theoretical performance limits. To achieve their full potential, parasitic non-radiative losses and bandgap instabilities from ionic segregation must be fundamentally understood and eliminated. HYPERION will address these issues by i) elucidating the origins of non-radiative decay and ion segregation in films and devices, ii) devising means to eliminate these processes, and iii) implementing optimised materials into boundary-pushing PV and LED devices. This will be achieved through a groundbreaking hierarchical analysis of the perovskite structures that not only characterises thin films and interfaces, but also the sub-units that comprise them, including grain-to-grain and sub-granular properties. The optoelectronic behaviour on these scales will be simultaneously correlated with local structural and chemical properties. HYPERION will use this fundamental understanding to eliminate non-radiative losses and ionic segregation on all scales through passivation treatments and compositional control. Addressing these knowledge gaps in the operation of perovskites will produce fundamental semiconductor science discoveries as well as illuminate routes to yield optimised and functional perovskites across the broad bandgap range 1.2\u20133.0 eV. These will be used to demonstrate all-perovskite tandem PV devices with efficiency exceeding crystalline silicon (26%), and white light LEDs with efficacies surpassing fluorescent light (50 lm/W). The work will realise the promise of perovskite technology as a versatile and scalable energy solution to secure a sustainable future.", "To": ["2022-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["756962"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["WEIZMANN INSTITUTE OF SCIENCE", "WEIZMANN INSTITUTE OF SCIENCE"], "EU_Contribution": ["EUR 1 499 999"], "Project_Title": ["Decoding the host-pathogen interspecies crosstalk at a multiparametric single-cell level"], "Total_Cost": ["EUR 1 499 999"], "Country": ["Israel", "Israel"], "Project_ACR": ["DecodingInfection"], "Technology_Description": "Bacterial pathogens remain a significant threat to global health, necessitating a better understanding of host-pathogen biology. While various evidence point to early infection as a key event in the eventual progression to disease, our recent preliminary data show that during this stage, highly adaptable and dynamic host cells and bacteria engage in complex, diverse interactions that contribute to well-documented heterogeneous outcomes of infection. However, current methodologies rely on measurements of bulk populations, thereby overlooking this diversity that can trigger different outcomes. This application focuses on understanding heterogeneity during the first stages of infection in order to reduce the complexity of these interactions into informative readouts of population physiology and predictors of infection outcome. We will apply multiparametric single-cell analysis to obtain an accurate and complete description of infection with the enteric intracellular pathogen Salmonella of macrophages in vitro, and in early stages of mice colonization. We will characterize the molecular details that underlie distinct infection outcomes of individual encounters, to reconstruct the repertoire of host and pathogen strategies that prevail at critical stages of early infection.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["756653"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["THE UNIVERSITY OF EDINBURGH", "THE UNIVERSITY OF EDINBURGH"], "EU_Contribution": ["EUR 1 418 195"], "Project_Title": ["The Rise of Placental Mammals: Dissecting an Evolutionary Radiation"], "Total_Cost": ["EUR 1 418 195"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["PalM"], "Technology_Description": "Mammals are ubiquitous, with over 5000 species across the globe. But how did mammals become so successful? There is vigorous debate among palaeontologists: did mammals explosively diversify after a sudden environmental crisis knocked out dinosaurs at the end of the Cretaceous (~66 million years ago) or rise to dominance more slowly, alongside the dinosaurs? The debate persists because we still know very little about those mammals that flourished during the ~10 million years after the end-Cretaceous extinction (the early Paleogene), as they are largely ignored because their \u2018archaic\u2019 anatomy has long confounded palaeontologists. This project will use a wealth of newly discovered fossils and state-of-the-art analytical techniques to finally untangle the evolutionary story of these ~200 critical species. We will comprehensively study the anatomy of \u2018archaic\u2019 species using state-of-the-art imaging technology and build a species-level genealogy placing these long-mysterious mammals in the context of their Cretaceous forebears and modern mammals. Cutting-edge quantitative methods for studying evolution, including novel techniques developed here, will be applied to the family tree to date the origin of placental mammals and the major modern groups, determine what effect the end-Cretaceous extinction had on mammalian biodiversity, quantify the tempo and mode of the placental radiation, and explicitly test for potential drivers of mammalian diversification. This will give ground-breaking insight into how major groups become successful over evolutionary time and how biodiversity is affected and reset by dramatic environmental changes, a pressing concern in today\u2019s rapidly changing world.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["756226"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 491 909"], "Project_Title": ["Planetary accretion and migration in discs over all ages"], "Total_Cost": ["EUR 1 491 909"], "Country": ["Germany", "Germany"], "Project_ACR": ["PAMDORA"], "Technology_Description": "The goal of this ERC proposal is to make significant progress in our understanding how planetary systems form in protoplanetary discs. In this ambitious research programme I will answer these three key questions:", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2018-01-01"], "Project_ID": ["757448"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITAET ZU KOELN", "UNIVERSITAET ZU KOELN"], "EU_Contribution": ["EUR 1 499 891"], "Project_Title": ["The mechanical evolution from biting-chewing to piercing-sucking in insects"], "Total_Cost": ["EUR 1 499 891"], "Country": ["Germany", "Germany"], "Project_ACR": ["MECH-EVO-INSECT"], "Technology_Description": "Insects are extremely efficient feeders that impact on the world's ecosystems and our agriculture with their feeding capabilities. Insects evolved diverse mouthpart types during ~400 million years of evolution which allowed them to conquer many food recourses. How this feeding system evolved, in particular the transition from one mouthpart type to the other, is unclear. My idea represents the first extensive assessment of insect head mechanics applying latest semi-automatic workflows and engineering approaches to unravel the factors driving insect mouthpart evolution and performance. ", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["754290"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITAT WIEN", "UNIVERSITAT WIEN"], "EU_Contribution": ["EUR 1 497 202"], "Project_Title": ["Atomic precision materials engineering"], "Total_Cost": ["EUR 1 497 202"], "Country": ["Austria", "Austria"], "Project_ACR": ["ATMEN"], "Technology_Description": "Despite more than fifty years of scientific progress since Richard Feynman's 1959 vision for nanotechnology, there is only one way to manipulate individual atoms in materials: scanning tunneling microscopy. Since the late 1980s, its atomically sharp tip has been used to move atoms over clean metal surfaces held at cryogenic temperatures. Scanning transmission electron microscopy, on the other hand, has been able to resolve atoms only more recently by focusing the electron beam with sub-atomic precision. This is especially useful in the two-dimensional form of hexagonally bonded carbon called graphene, which has superb electronic and mechanical properties. Several ways to further engineer those have been proposed, including by doping the structure with substitutional heteroatoms such as boron, nitrogen, phosphorus and silicon. My recent discovery that the scattering of the energetic imaging electrons can cause a silicon impurity to move through the graphene lattice has revealed a potential for atomically precise manipulation using the \u00c5ngstr\u00f6m-sized electron probe. To develop this into a practical technique, improvements in the description of beam-induced displacements, advances in heteroatom implantation, and a concerted effort towards the automation of manipulations are required. My project tackles these in a multidisciplinary effort combining innovative computational techniques with pioneering experiments in an instrument where a low-energy ion implantation chamber is directly connected to an advanced electron microscope. To demonstrate the power of the method, I will prototype an atomic memory with an unprecedented memory density, and create heteroatom quantum corrals optimized for their plasmonic properties. The capability for atom-scale engineering of covalent materials opens a new vista for nanotechnology, pushing back the boundaries of the possible and allowing a plethora of materials science questions to be studied at the ultimate level of control.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["756277"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 2 498 485"], "Project_Title": ["Parallel Orthographic Processing and Reading"], "Total_Cost": ["EUR 2 498 485"], "Country": ["France", "France"], "Project_ACR": ["POP-R"], "Technology_Description": "The project centers on a new computational model, the POP-R model, that implements two original, and apparently contradictory, hypotheses with respect to the processing of orthographic information spanning several words during silent reading for meaning: 1) orthographic information spanning several words is processed in parallel and integrated within a single pool of location-invariant orthographic representations; 2) readers process multiple word identities in parallel and keep track of the positions of these words by associating word identities with spatiotopic locations in short-term memory. The apparent contradiction is solved in POP-R by the triangular connectivity between gaze-centered letter detectors, spatiotopic word identities, and location-invariant orthographic representations. Evidence in favor of the first hypothesis has been obtained with a novel Flanking Letters Lexical Decision task. The second hypothesis predicted the existence of a sentence superiority effect in a novel Rapid Parallel Visual Presentation paradigm, for which we have preliminary evidence. Other key predictions of the POP-R model will be tested in behavioral experiments using these new techniques, and EEG and MEG recordings will be used to specify the spatio-temporal dynamics of the neural processes underlying orthographic pooling and parallel word identification. Experiments with primary school children will plot the developmental trajectory of these processes, and sentence reading experiments measuring eye-movements and ERPs will be used to further test the model. The project incorporates both theoretical and methodological innovation within a novel perspective on reading that places orthographic processing at the very heart of the reading network. This new perspective is expected to facilitate the integration of knowledge concerning low-level visual processing and eye-movement control with higher-level semantic and syntactic processing during silent reading for meaning.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-10-01"], "Project_ID": ["742141"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 1 930 437"], "Project_Title": ["Tunable optoelectronic devices by strain engineering of 2D semiconductors"], "Total_Cost": ["EUR 1 930 437"], "Country": ["Spain", "Spain"], "Project_ACR": ["2D-TOPSENSE"], "Technology_Description": "The goal of 2D-TOPSENSE is to exploit the remarkable stretchability of two-dimensional semiconductors to fabricate optoelectronic devices where strain is used as an external knob to tune their properties.", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-03-01"], "Project_ID": ["755655"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSIDAD DE MALAGA", "UNIVERSIDAD DE MALAGA"], "EU_Contribution": ["EUR 1 203 125"], "Project_Title": ["Advanced Analytics to Empower the Small Flexible Consumers of Electricity"], "Total_Cost": ["EUR 1 203 125"], "Country": ["Spain", "Spain"], "Project_ACR": ["FlexAnalytics"], "Technology_Description": "David against Goliath: Could small consumers of electricity compete in the wholesale markets on equal footing with the other market agents? Yes, they can and FlexAnalytics will show how.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["755705"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["BRITISH SCHOOL AT ATHENS"], "EU_Contribution": ["EUR 164 653,20"], "Project_Title": ["TRAvelling Ceramic Technologies as markers of human mobility in the Aegean"], "Total_Cost": ["EUR 164 653,20"], "Country": ["United Kingdom"], "Project_ACR": ["TRACT"], "Technology_Description": "The main aim of TRACT is to demonstrate that the informed and interdisciplinary study of ancient pottery can shed new light on past human mobility. Based on the premise that the spread of technology involved in pottery making requires the physical movement of people, the project will adopt an inter-disciplinary methodology designed to investigate instances of technological transfer and hence mobility of potters. The methodology comprises macroscopic study of the vessel-forming methods in combination with petrographic and chemical analysis of pottery and raw material samples. An important addition is the study of modern instances of potters\u2019 mobility in the Aegean. Altogether, this represents a novel approach, which will be employed to a specific study focused on potters from the island of Aegina during the Late Bronze Age. TRACT will investigate the spread of a particular pottery tradition developed on the island of Aegina along the Euboean Gulf, an important corridor that facilitated movement of goods and people. Furthermore, the chosen case study will aim to shed light on the underpinnings of such movement, its duration, scale, as well as interaction of potters with new landscapes and receiving communities. Therefore, TRACT will contribute to the current debate on mobility by presenting thoroughly researched case study of craftsmen mobility, and elaborate a coherent methodology that can be universally applied. The choice of the Fitch Laboratory of the British School at Athens as a hosting institution will not only enable a high-level training through research but also, due to the supervisor\u2019s interest in mobility of potters\u2019 mobility and previous research on pottery production on the island of Aegina, it constitutes a perfect match that will provide a substantial boost to career opportunities for the experienced researcher and strengthen the position of the Laboratory as a centre of excellence for the study of craftspeople mobility.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations"], "From": ["2017-10-01"], "Project_ID": ["753569"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN", "LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN"], "EU_Contribution": ["EUR 1 636 710"], "Project_Title": ["Armoring multifunctional T cells for cancer therapy"], "Total_Cost": ["EUR 1 636 710"], "Country": ["Germany", "Germany"], "Project_ACR": ["ARMOR-T"], "Technology_Description": "Adoptive T cell therapy (ACT) is a powerful approach to treat even advanced cancer diseases where poor prognosis calls for innovative treatments. However ACT is critically limited by insufficient T cell infiltration into the tumor, T cell activation at the tumor site and local T cell suppression. Few advances have been made in the field to tackle these limitations besides increasing T cell activation. My group has focussed on these unaddressed issues but came to realise that tackling these one by one will not be sufficient. I have developed a panel of unpublished chemokine receptors and innovative modular antibody-activated receptors which have the potential to overcome the limitations of ACT against solid tumors. This ground-breaking portfolio places my group in the unique position to address combination of synergistic receptors and enable cellular therapies in previously unsuccessful indications. My project will provide the rationale for provision of an effective cancer treatment. The goal is to develop the next generation of ACT through T cell engineering both by forced expression of migratory and activating receptors and simultaneous deletion of immune suppressive molecules by gene editing. ARMOR-T will provide the basis for further preclinical and clinical development of a pioneering cellular product devoid of the limitations of available products to date. I will prove 1) synergy between migratory and modular activating receptors, 2) feasibility to integrate gene editing into a T cell expansion protocol, 3) synergy between gene editing, migratory and modular receptors and 4) efficacy, safety and mode of action. The main work of the project will be carried out in models of pancreatic cancer. The ARMOR-T platform will subsequently be translated to other cancer entities where response to ACT is likely such as melanoma, breast or colon cancer, providing less toxic and more effective therapies to otherwise untreatable disease.", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["756017"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON", "UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 1 471 530"], "Project_Title": ["The Politics of Climate Change Loss and Damage"], "Total_Cost": ["EUR 1 471 530"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["CCLAD"], "Technology_Description": "The way in which normative principles (\u201cnorms\u201d) matter in world politics is now a key area of international relations research. Yet we have limited understanding of why some norms emerge and gain traction globally whereas others do not. The politics of loss and damage related to climate change offers a paradigm case for studying the emergence of - and contestation over - norms, specifically justice norms. The parties to the UN Framework Convention on Climate Change (UNFCCC) have recently acknowledged that there is an urgent need to address the inevitable, irreversible consequences of climate change. Yet within this highly contested policy area - which includes work on disaster risk reduction; non-economic losses (e.g. loss of sovereignty); finance and climate-related migration - there is little consensus about what loss and damage policy means or what it requires of the global community, of states and of the (current and future) victims of climate change. Relying on an interdisciplinary theoretical approach and an ethnographic methodology that traverses scales of governance, my project - The Politics of Climate Change Loss and Damage (CCLAD) - will elucidate the conditions under which a norm is likely to become hegemonic, influential, contested or reversed by introducing a new understanding of the fluid nature of norm-content. I argue that norms are partly constituted through the practices of policy-making and implementation at the international and national level. The research will examine the micro-politics of the international negotiations and implementation of loss and damage policy and also involves cross-national comparative research on domestic loss and damage policy practices. Bringing these two streams of work together will allow me to show how and why policy practices shape the evolution of climate justice norms. CCLAD will also make an important methodological contribution through the development of political ethnography and \u201cpractice-tracing\u201d methods.", "To": ["2023-04-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-05-01"], "Project_ID": ["755753"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "KALAHARI RESEARCH TRUST"], "EU_Contribution": ["EUR 2 499 244"], "Project_Title": ["Effects of group dynamics on selection, development and demography in cooperative vertebrates"], "Total_Cost": ["EUR 2 499 244"], "Country": ["United Kingdom", "United Kingdom", "South Africa"], "Project_ACR": ["Group-Dynamics-TCB"], "Technology_Description": "In social animals, the characteristics and dynamics of groups affect the development of individuals, the selection pressures operating on them and the demography of populations. Using existing study populations of two social mammals (Kalahari meerkats and Damaraland mole-rats) that offer unique and complementary opportunities for research, we shall (1) explore the effects of variation in group size on growth, behaviour, hormonal status and gene regulation in both species and test suggestions that (i) increasing group size generates divergence in development among group members and the formation of incipient castes and (ii) that breeding extends female longevity rather than reducing it; (2) assess the extent and causes of variation in group longevity and in the frequency with which groups generate new breeding units, model the relative impact of selection operating at different levels on the evolution of cooperation, and investigate whether there is any indication that the behaviour of individuals is adapted to increasing group persistence or proliferation; (3) examine the effects of group size and group dynamics on the dynamics of populations and their responses to variation in rainfall, temperature and epidemic disease (TB), generalise these models to explore the population dynamics of cooperative breeders and explore their consequences for the evolution of cooperative breeding. Our work involves novel approaches to the measurement and analysis of development, communication and gene regulation in wild animals, and to modelling multi-level selection and the dynamics of hierarchically structured populations. It will provide insight into the social mechanisms affecting individual development, multi-level selection and the population dynamics and management of group-living animals.", "To": ["2023-06-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2018-07-01"], "Project_ID": ["742808"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSITE LIBRE DE BRUXELLES", "UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6"], "EU_Contribution": ["EUR 2 200 000"], "Project_Title": ["IASI - Flux and temperature"], "Total_Cost": ["EUR 2 200 000"], "Country": ["France", "France", "Belgium", "France"], "Project_ACR": ["IASI-FT"], "Technology_Description": "IASI - Flux and temperature", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["742909"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["WEIZMANN INSTITUTE OF SCIENCE", "WEIZMANN INSTITUTE OF SCIENCE"], "EU_Contribution": ["EUR 1 499 990"], "Project_Title": ["Stromal stress networks underlying phenotypic plasticity and tumor fitness"], "Total_Cost": ["EUR 1 499 990"], "Country": ["Israel", "Israel"], "Project_ACR": ["StroMaP"], "Technology_Description": "The contribution of genetic and epigenetic changes to rewiring of cancer cells into their malignant state has been much studied. But tumors are more than cancer cells and the tumor microenvironment (TME) is a key player in tumor progression. We lack an overarching view of how, despite being genomically stable, the TME is heterogeneously reprogrammed across time and space to promote evolution of aggressive disease.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["754320"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["LINKOPINGS UNIVERSITET", "LINKOPINGS UNIVERSITET", "UNIVERSITY OF KENT"], "EU_Contribution": ["EUR 2 261 522,73"], "Project_Title": ["Patents as Scientific Information, 1895-2020"], "Total_Cost": ["EUR 2 261 522,73"], "Country": ["Sweden", "Sweden", "United Kingdom"], "Project_ACR": ["PASSIM"], "Technology_Description": "\u201cHistory will remember Barack Obama as the great Slayer of Patent Trolls.\u201d The headline from the 2014 March 20 issue of Wired credits POTUS with, perhaps, an unexpected feat. Referring to companies in the sole business of enforcing patents beyond their actual value, trolls are a recent installment in the history of an intellectual property whose ubiquitousness the Latin word PASSIM (\u201chere and there, everywhere\u201d) neatly captures. In the eye of the storm stands the patent bargain: disclosure of information in return for a limited monopoly. This contractual moment makes patents a source of information, the basis of new innovation. Or does it? By posing this simple question, PASSIM\u2019s bold take on the legitimacy of intellectual property in the governance of informational resources follow patents as legal and informational documents during three historical \u201cpatent phases,\u201d producing a visionary and theoretically savvy interpretation of intellectual property that stems from its humanities-based and interdisciplinary project design. PASSIM shows a way out of current analytical gridlocks that earmark the understanding of the role of intellectual property in knowledge infrastructures\u2014most notably the enclosure/openness dichotomy\u2014and provides a fresh take on the complexity of informational processes. A key steppingstone in the PI\u2019s career, her own contribution to PASSIM will be a work of synthesis, highlighting major tendencies in the history of patents as scientific information from 1895 to the present. Four complementary empirical studies target specific themes that strengthen PASSIM\u2019s validity and impact: questions of copyrights in patents, scientists\u2019 patenting strategies both historically and today, the relationship between bibliometrics and patentometrics, and the status of the patent as a legal and informational document. Outputs include workshops, articles, monographs, policy papers and documentation of the project\u2019s experiences with interdisciplinary self-reflexivity.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["741095"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITA COMMERCIALE LUIGI BOCCONI", "UNIVERSITA COMMERCIALE LUIGI BOCCONI"], "EU_Contribution": ["EUR 1 276 250"], "Project_Title": ["European Integration, Populism and European Cities"], "Total_Cost": ["EUR 1 276 250"], "Country": ["Italy", "Italy"], "Project_ACR": ["EUROPOPULISM"], "Technology_Description": "Why is it so difficult to achieve further European political integration? This question motivates the first part of the project. The standard approach in economics presumes that integration of countries reflects a tradeoff between economic benefits and the cost of cultural heterogeneity. To assess this tradeoff, we exploit survey data to quantify cultural heterogeneity within and between EU countries, comparing it to the US. We also investigate time variation, to assess whether economic integration led to cultural convergence. Finally, exploiting regional variation, we seek to identify a cultural core and compare it to the economic core of the EU. We conjecture the following conclusion: although European economic integration has not led to cultural convergence, the primary obstacle to integration is not cultural heterogeneity per se, but the presence of other barriers, such as national identities or national institutions, which amplify its effects.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["741643"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["DETERMINING THE FUNCTIONAL CONSEQUENCES OF TRANSCRIPTIONAL ENHANCER ACTIVATION ON ALTERNATIVE SPLICING DURING EMT"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["ESEMT"], "Technology_Description": "Alternative splicing (AS) is a highly regulated process that is essential for creating the protein diversity required for correct cell-type specification. Misregulation of AS programs can lead to cellular dysfunction, developmental problems and disease, such as cancer. Understanding how alternative splicing is regulated during development and disease is therefore capital.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2017-10-01"], "Project_ID": ["752595"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["TECHNISCHE UNIVERSITAT DARMSTADT", "TECHNISCHE UNIVERSITAT DARMSTADT"], "EU_Contribution": ["EUR 2 548 298"], "Project_Title": ["antiProton Unstable Matter Annihilation"], "Total_Cost": ["EUR 2 548 298"], "Country": ["Germany", "Germany"], "Project_ACR": ["PUMA"], "Technology_Description": "One of the most fascinating quantum phenomena in nuclear physics is the occurrence of neutron halos and neutron skins in very neutron rich atomic nuclei. Thick neutron skins and halos, not yet evidenced in medium mass nuclei, would be unique low-density neutron matter accessible in the laboratory. Nuclear shell structure is also known to change with the number of protons and neutrons. The nuclear structure of very heavy nuclei at and above Z=100 is barely known, and the existence of new long-lived heavy isotopes is still an open question. The above fundamental phenomena related to the unbalance of neutron and protons in unstable nuclei are essential to understand the complex nature of nuclei and related astrophysical processes. ", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["726276"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITE CATHOLIQUE DE LOUVAIN", "UNIVERSITE CATHOLIQUE DE LOUVAIN", "UNIVERSITY OF LONDON"], "EU_Contribution": ["EUR 2 495 335"], "Project_Title": ["The origin and early development of philosophy in tenth-century al-Andalus: the impact of ill-defined materials and channels of transmission."], "Total_Cost": ["EUR 2 495 335"], "Country": ["Belgium", "Belgium", "United Kingdom"], "Project_ACR": ["PhilAnd"], "Technology_Description": "The objective of PhilAnd is to conduct a large-scale exploration of how, and under which form, philosophy appeared for the first time in al-Andalus. This issue is pivotal to understanding the history of sciences and ideas, and the role of the Arab-Muslim world in this transfer to Medieval Europe. Its relevance today also lies in the fact that it addresses questions of cultural and religious identities, since the formative stage of philosophy in al-Andalus proved decisive in shaping the intellectual background of many later authors from the Peninsula, whether Muslims, Jews, or Christians. At the crossroads of major lines of enquiries in scholarship and in line with recent discoveries having important chronological implications, PhilAnd focuses on the 10th century, a period usually disregarded by historians on the assumption that philosophy as such was not cultivated in the Iberian Peninsula before the 11th-12th centuries. Its originality is also to put emphasis on \u2018ill-defined\u2019 materials and channels of transmission, a field which remains largely unexplored. This project consists of five topics designed for highly-specialised scholars, and of another three transversal types of exploration conducted in the form of conferences convened with leading experts in the world. The final objectives are to test the hypothesis: 1) that the emergence of philosophy in al-Andalus significantly predates the currently accepted time; and 2) that the impact of this formative stage was considerably wider than commonly acknowledged. This project also seeks to provide a better evaluation of the originality of the first Andalus\u012b philosophers with respect to their Oriental forerunners. This cutting-edge investigation is likely to stimulate major changes in our perception of how this primeval stage of philosophy in al-Andalus determined the subsequent developments of rational speculation among the three monotheistic communities of the Peninsula and the intellectual formation of Europe.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["740618"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["THE HEBREW UNIVERSITY OF JERUSALEM", "THE HEBREW UNIVERSITY OF JERUSALEM"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Decoding the Epigenomic Regulatory Code by the Use of Single Cell Technologies"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Israel", "Israel"], "Project_ACR": ["SC-EpiCode"], "Technology_Description": "Chromatin regulators adjust genome functions by modifying chromatin states. Comprehensive characterization of chromatin states, associations of chromatin regulators, and expression profiles is crucial for investigating: 1.Cellular differentiation triggers. 2.The nature of the underlying chromatin regulatory mechanisms. 3.The effect of cellular heterogeneity, and 4. How chromatin affects mRNA expression. Mapping chromatin states by sequencing immunoprecipitated chromatin (ChIP-seq) provides an extraordinary resource for studying cellular states. However, a major shortcoming is that the profiles reflect a composite average over the studied cell population, concealing important information about the underlying subpopulations. To address this hurdle, I pioneered Drop-Seq, a novel drop based microfluidic technology for single cell ChIP-seq and RNA-seq. Applying the technique to thousands of embryonic stem (ES) cells, we identified a spectrum of sub-populations defined by differences in chromatin signatures of pluripotency and differentiation priming. However, despite initial progress, the extent and significance of chromatin-state heterogeneity and its relationship with mRNA expression remain largely uncharted. The central aim of this proposal is to develop a novel framework to systematically characterize cell-to-cell variability at the epigenomic level. Our approach will include the development of technology enabling ChIP-seq and RNA-seq on the same cell. We will also exploit drop-based microfluidics to develop a robust CRISPR/Cas9-based approach to assess single and multiple perturbations. Finally, we will apply these innovative technologies to questions about cellular heterogeneity and epigenomic regulation during early differentiation of ES cells. This proposal will reveal the function and interplay between chromatin regulators, histone marks and transcription events, and shed light on the underlying regulation leading to cell fate decisions.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["715260"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["UNIVERSITAT DE VALENCIA", "UNIVERSITAT DE VALENCIA"], "EU_Contribution": ["EUR 1 499 587"], "Project_Title": ["Fluorescence-based photosynthesis estimates for vegetation productivity monitoring from space"], "Total_Cost": ["EUR 1 499 587"], "Country": ["Spain", "Spain"], "Project_ACR": ["SENTIFLEX"], "Technology_Description": "Global food security will remain a worldwide concern for the next 50 years and beyond. Agricultural production undergoes an increasing pressure by global anthropogenic changes, including rising population, increased protein demands and climatic extremes. Because of the immediate and dynamic nature of these changes, productivity monitoring measures are urgently needed to ensure both the stability and continued increase of the global food supply. Europe has expressed ambitions to keep its fingers on the pulse of its agricultural lands. In response to that, this proposal - named SENTIFLEX - is dedicated to developing a European vegetation productivity monitoring facility based on the synergy of Sentinel-3 (S3) with FLEX satellite fluorescence data. ESA's 8th Earth Explorer FLEX is the first mission specifically designed to globally measure Sun-Induced chlorophyll Fluorescence (SIF) emission from terrestrial vegetation. These two European Earth observation missions offer immense possibilities to increase our knowledge of the basic functioning of the Earth\u2019s vegetation, i.e., the photosynthetic activity of plants resulting in carbon fixation. Two complementary approaches are envisioned to realize quantification of photosynthesis through satellite SIF and S3. First, the work seeks to advance the science in establishing and consolidating relationships between canopy-leaving SIF and unbiased estimates of photosynthesis of the plants, thereby disentangling the role of dynamic vegetative and atmospheric variables. Second, consolidated relationships between SIF and photosynthesis will be used to build a FLEX-S3 data processing assimilation scheme through process-based vegetation models that will deliver spatiotemporally highly resolved information on Europe\u2019s vegetation productivity. To streamline all these datasets into a prototype vegetation productivity monitoring facility, new data processing concepts will be introduced such as the emulation of radiative transfer models.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["755617"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET", "KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 1 999 909"], "Project_Title": ["Criminal Entanglements.A new ethnographic approach to transnational organised crime."], "Total_Cost": ["EUR 1 999 909"], "Country": ["Denmark", "Denmark"], "Project_ACR": ["CRIMTANG"], "Technology_Description": "Linked to terrorism, moral breakdown, and societal decay, Transnational Organised Crime (TOC) has come to embody current global anxieties as a figure of fear and cause of disquiet. Yet despite its central position on the social and political radar, our knowledge of it remains limited and fragmentary. Quantitative analyses may have identified the scale of the problem, but its underlying socio-cultural logic and practices remain under-researched and largely obscure. TOC is on the rise, and we need better insights into how it develops and expands, who engages in it and why, and how it is linked to and embedded in social networks that straddle countries and contexts. ", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["725194"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["LEIBNIZ-INSTITUT FUER PHOTONISCHE TECHNOLOGIEN E.V.", "LEIBNIZ-INSTITUT FUER PHOTONISCHE TECHNOLOGIEN E.V.", "UNIVERSITY OF DUNDEE"], "EU_Contribution": ["EUR 1 997 973"], "Project_Title": ["Holographic super-resolution micro-endoscopy for in-vivo applications"], "Total_Cost": ["EUR 1 997 973"], "Country": ["Germany", "Germany", "United Kingdom"], "Project_ACR": ["LIFEGATE"], "Technology_Description": "Complexity of living matter currently poses the most significant barrier to modern in-vivo microscopy. Fuelled by various branches of life sciences, the race is now to increase the penetration depth of super-resolution imaging inside living organisms. Additionally, no high-resolution in-vivo imaging technique has ever been introduced into medical, particularly surgical practice. ", "To": ["2022-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["724530"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["AGENCE NATIONALE DE LA RECHERCHE", "FONDS ZUR F\u00d6RDERUNG DER WISSENSCHAFTLICHEN FORSCHUNG", "FONDS NATIONAL DE LA RECHERCHE SCIENTIFIQUE", "BULGARIAN NATIONAL SCIENCE FUND", "SCHWEIZERISCHER NATIONALFONDS ZUR FORDERUNG DER WISSENSCHAFTLICHEN FORSCHUNG", "TECHNOLOGICKA AGENTURA CESKE REPUBLIKY", "SIHTASUTUS EESTI TEADUSAGENTUUR", "MINISTERIO DE ECONOMIA, INDUSTRIA Y COMPETITIVIDAD", "SUOMEN AKATEMIA", "AN TUDARAS UM ARD OIDEACHAS", "MINISTERO DELL'ISTRUZIONE, DELL'UNIVERSITA' E DELLA RICERCA", "Lietuvos mokslo taryba", "NARODOWE CENTRUM NAUKI", "Unitatea Executiva pentru Finantarea Invatamantului Superior, a Cercetarii, Dezvoltarii si Inovarii", "SLOVENSKA AKADEMIA VIED", "TURKIYE BILIMSEL VE TEKNOLOJIK ARASTIRMA KURUMU", "THE ENGINEERING AND PHYSICAL SCIENCES RESEARCH COUNCIL"], "EU_Contribution": ["EUR 4 500 787,50"], "Project_Title": ["European coordinated research on long-term ICT and ICT-based scientific challenges"], "Total_Cost": ["EUR 14 438 750"], "Country": ["France", "Austria", "Belgium", "Bulgaria", "Switzerland", "Czech Republic", "Estonia", "Spain", "Finland", "Ireland", "Italy", "Lithuania", "Poland", "Romania", "Slovakia", "Turkey", "United Kingdom"], "Project_ACR": ["CHIST-ERA III"], "Technology_Description": "\"CHIST-ERA is a network of research funding organisations in Europe and beyond with programmes in ICST (Information and Communication Science and Technology), at the intersection of the FET and the ICT domains. CHIST-ERA III aims at supporting transnational research projects addressing long-term scientific challenges in the domain of ICT or at the interface between this and other domains. It also fosters the maturation of the corresponding research topics and the structuration of the corresponding communities. Another goal is to encourage Open Science best practices. In the framework of CHIST-ERA III, two joint transnational calls are planned (CHIST-ERA Calls 2017 and 2018), each covering two topics. The two topics for Call 2017 are \"\"Object recognition and manipulation by robots: data sharing and experiment reproducibility\"\" and \"\"Industrial big data and process modelling for smart factories\"\". The two topics for Call 2018 will be decided toward the end of 2017.\"", "To": ["2022-11-30, ongoing project"], "Meta": [""], "Topic_s": ["FETPROACT-02-2017 - FET ERANET Cofund"], "Funding_scheme": ["ERA-NET-Cofund - ERA-NET Cofund"], "Coordinated_in": ["France"], "Activity": ["Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Other", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations"], "From": ["2017-12-01"], "Project_ID": ["768977"], "Call_for_Proposal": ["FETPROACT-2017"]}, -{"Partners": ["WEIZMANN INSTITUTE OF SCIENCE", "WEIZMANN INSTITUTE OF SCIENCE"], "EU_Contribution": ["EUR 2 488 306"], "Project_Title": ["Towards evidence-based combinations of approved and novel cancer drugs"], "Total_Cost": ["EUR 2 488 306"], "Country": ["Israel", "Israel"], "Project_ACR": ["onCOMBINE"], "Technology_Description": "Background: Molecular targeted therapy (TT; e.g., monoclonal antibodies, mAbs, and protein kinase inhibitors, PKIs) intercepts oncogene and other addictions of tumours. However, unlike chemotherapy, which employs cocktails of drugs, only rarely does TT harness poly-pharmacology. Because lung cancer is the major cause of oncology related fatalities and many driver mutations are known, this disease offers opportunities for establishing and generalizing novel TT combinations and their interface with the immune system. ", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["740469"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "THE REGENTS OF THE UNIVERSITY OF CALIFORNIA"], "EU_Contribution": ["EUR 171 792,60"], "Project_Title": ["Gravity and Kinematic Space"], "Total_Cost": ["EUR 171 792,60"], "Country": ["United Kingdom", "United States"], "Project_ACR": ["MOSK"], "Technology_Description": "The experienced researcher, Dr. Benjamin Mosk, wants to investigate a description of gravity in terms of non-local degrees of freedom. This approach is motivated by the AdS/CFT correspondence and the recent progress made by Dr. Mosk and his collaborators on the subject of kinematic space, the space of totally geodesic sub manifolds of Anti de Sitter (AdS) space. Dr. Mosk proposes to generalize the idea of kinematic space and the description of dynamical fields on this space to more general classical geometries, starting with the AdS-Schwarzschild geometry. The scientific objective of this project is to make progress towards a fundamental description of gravity at the non-classical level, which is arguably the largest open question in theoretical physics.", "To": ["2019-09-30, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["750838"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UPPSALA UNIVERSITET", "UPPSALA UNIVERSITET"], "EU_Contribution": ["EUR 1 497 059"], "Project_Title": ["Molecularly defined models of human childhood brain tumors"], "Total_Cost": ["EUR 1 497 059"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["Medulloblastoma"], "Technology_Description": "MYC proteins like MYC and MYCN are transcription factors that are mis-regulated in more than half of all types of human cancer including medulloblastoma, the most common brain malignancy in children. The two main challenges that can guide research in the field of pediatric brain tumors is improving survival and reducing long-term detriments due to treatment toxicities, especially from craniospinal radiotherapy. Medulloblastoma is suggested to originate from specific cells in the small brain, cerebellum. These brain tumors have recently been classified into four distinct molecular subgroups and subgroup-specific driver genes have been suggested. However, the precise role of such drivers in tumor initiation and their importance in specifying particular subgroups has not been sufficiently evaluated in proper cells of medulloblastoma origin.", "To": ["2020-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-05-01"], "Project_ID": ["640275"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["UPPSALA UNIVERSITET", "UPPSALA UNIVERSITET"], "EU_Contribution": ["EUR 125 318,75"], "Project_Title": ["Soccermatics: data for football fans and clubs"], "Total_Cost": ["EUR 125 318,75"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["SOCCERMATICS"], "Technology_Description": "Data plays an increasingly important role in sport, from monitoring of fitness of athletes to success statistics in baseball. In football (soccer) the team performance is more important than the performance of any one individual. While every team has its star players, it is the ability of the team to function as a unit that is the key to its success. For the data analyst, this presents a challenge: how to measure, understand and improve team performance. My research during an ERC funded action (IDCAB) has revolved around devising exactly this type of analysis methods. Starting with my work on measuring and understanding animal groups in the ERC action, I have gone on to develop a set of tools for looking at the collective action on the football pitch. ", "To": ["2019-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["727646"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["UPPSALA UNIVERSITET", "UPPSALA UNIVERSITET", "KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 1 145 879"], "Project_Title": ["Dynamics of Supersymmetry in Curved Space"], "Total_Cost": ["EUR 1 145 879"], "Country": ["Sweden", "Sweden", "Denmark"], "Project_ACR": ["CurvedSusy"], "Technology_Description": "Quantum field theory provides a theoretical framework to explain quantitatively natural phenomena as diverse as the fluctuations in the cosmic microwave background, superconductivity, and elementary particle interactions in colliders. Even if we use quantum field theories in different settings, their structure and dynamics are still largely mysterious. Weakly coupled systems can be studied perturbatively, however many natural phenomena are characterized by strong self-interactions (e.g. high T superconductors, nuclear forces) and their analysis requires going beyond perturbation theory. Supersymmetric field theories are very interesting in this respect because they can be studied exactly even at strong coupling and their dynamics displays phenomena like confinement or the breaking of chiral symmetries that occur in nature and are very difficult to study analytically.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["639220"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "DEUTSCHES KREBSFORSCHUNGSZENTRUM", "UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA", "ACADEMISCH ZIEKENHUIS GRONINGEN", "MAGYAR TUDOMANYOS AKADEMIA SZEGEDIBIOLOGIAI KUTATOKOZPONT", "Epiontis GmbH", "CLINICAGENO LIMITED"], "EU_Contribution": ["EUR 2 797 697,16"], "Project_Title": ["Epigenetic regulation of endocrine therapy resistance in breast cancer: A systems medicine approach to predict treatment outcome"], "Total_Cost": ["EUR 2 797 697,16"], "Country": ["Netherlands", "United Kingdom", "Germany", "Italy", "Netherlands", "Hungary", "Germany", "United Kingdom"], "Project_ACR": ["EpiPredict"], "Technology_Description": "The mission of EpiPredict is to train a multidisciplinary cohort of young researchers in a new approach to fully exploit the epigenetics of complex diseases. The 12 early-stage researchers (ESRs) will focus on a narrowly defined case, Tamoxifen-induced resistance in Estrogen Receptor positive (ER+) breast cancer, considering five resistance interacting pathways. Given the frequent Tamoxifen treatment failure, resistance prevention and reversal is an urgent clinical problem that is central in EpiPredict. The EpiPredict intersectorial training programme employs a timely systems medicine approach combining next-generation systematic epigenetic, gene/protein profiling with innovative gene-specific epigenetic interference technologies for iterative computational modelling. Together the ESRs will identify key epigenetic changes underlying Tamoxifen induced resistance. This will provide an important step towards diagnostic markers/tools to predict treatment outcome and response monitoring setting the scene for breast cancer personalized medicine. The fellows will be trained by experts from 6 academic and 2 non-academic beneficiaries and 7 partner organizations (1 academic, 6 non-academic including industrial/socio-public parties) and 5 visiting scientists, from fields ranging from epigenetics to both computation and medicine. Strong involvement of the private sector ensures exploitation of EpiPredict achievements and exposure of the ESRs to an entrepreneurial mindset. ", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["642691"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["\"NATIONAL CENTER FOR SCIENTIFIC RESEARCH \"\"DEMOKRITOS\"\"\"", "NATIONAL OBSERVATORY OF ATHENS", "HELLENIC CENTRE FOR MARINE RESEARCH", "ETHNIKO IDRYMA EREVNON", "ATHINA-EREVNITIKO KENTRO KAINOTOMIAS STIS TECHNOLOGIES TIS PLIROFOFORIAS, TON EPIKOLNONION KAI TIS GNOSIS", "IDRIMA MEIZONOS ELLINISMOU", "EPISTIMI EPIKOINONIA"], "EU_Contribution": ["EUR 160 000"], "Project_Title": ["Researcher's Night: meeting science and your next door scientist"], "Total_Cost": ["EUR 160 000"], "Country": ["Greece", "Greece", "Greece", "Greece", "Greece", "Greece", "Greece"], "Project_ACR": ["REN-ATHENS"], "Technology_Description": "A diverse team of experts in scientific research and science communication from leading Research Institutes and Educational Organizations located in the Athens Metropolitan area is formed to organize the Researcher's Night activities for the years 2014 and 2015. By adopting the concept \u201cScience invites People\u201d, we propose a large scale REN, in 2014, at NCSR Demokritos, the largest Science Research campus in Attica, and a similar event in 2015, at IME a multiplex where science meets entertainment and exploration, organized by the National Observatory of Athens . ", "To": ["2015-10-31, closed project |"], "Meta": [""], "Topic_s": ["MSCA-NIGHT-2014 - European Researchers' Night (NIGHT)"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Greece"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Other"], "From": ["2014-05-01"], "Project_ID": ["633335"], "Call_for_Proposal": ["H2020-MSCA-NIGHT-2014"]}, -{"Partners": ["INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE", "ABERYSTWYTH UNIVERSITY", "AGENZIA LUCANA DI SVILUPPO E DI INNOVAZIONE IN AGRICOLTURA", "ASA ADVANCED SOLUTIONS ACCELERATOR", "AARHUS UNIVERSITET", "COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION", "STICHTING WAGENINGEN RESEARCH", "FORSCHUNGSZENTRUM JULICH GMBH", "LEIBNIZ - INSTITUT FUER PFLANZENGENETIK UND KULTURPFLANZENFORSCHUNG", "HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH", "INSTYTUT GENETYKI ROSLIN POLSKIEJ AKADEMI NAUK", "INRA TRANSFERT S.A.", "MAGYAR TUDOMANYOS AKADEMIA SZEGEDIBIOLOGIAI KUTATOKOZPONT", "PHENOSPEX BV", "SLOVENSKA POLNOHOSPODARSKA UNIVERSITA V NITRE (SLOVAK AGRICULTURAL UNIVERSITY IN NITRA)", "UNIVERSITE CATHOLIQUE DE LOUVAIN", "KOBENHAVNS UNIVERSITET", "HELSINGIN YLIOPISTO", "THE UNIVERSITY OF NOTTINGHAM", "VIB", "VSN INTERNATIONAL LTD", "WAGENINGEN UNIVERSITY"], "EU_Contribution": ["EUR 9 999 999,50"], "Project_Title": ["European Plant Phenotyping Network 2020"], "Total_Cost": ["EUR 10 220 249,50"], "Country": ["France", "United Kingdom", "Italy", "France", "Denmark", "Australia", "Netherlands", "Germany", "Germany", "Germany", "Poland", "France", "Hungary", "Netherlands", "Slovakia", "Belgium", "Denmark", "Finland", "United Kingdom", "Belgium", "United Kingdom", "Netherlands"], "Project_ACR": ["EPPN2020"], "Technology_Description": "EPPN2020 will provide European public and private scientific sectors with access to a wide range of state-of-the-art plant phenotyping facilities, techniques and methods. It will aid the community in progressing towards excellence across the whole phenotyping pipeline, involving sensors and imaging techniques, data analysis in relation to environmental conditions, data organization and storage, data interpretation in a biological context and meta-analyses of experiments. It builds upon the starting community project EPPN and will coordinate its activities with the ESFRI infrastructure EMPHASIS and with national programs.", "To": ["2021-04-30, ongoing project"], "Meta": [""], "Topic_s": ["INFRAIA-01-2016-2017 - Integrating Activities for Advanced Communities"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["731013"], "Call_for_Proposal": ["H2020-INFRAIA-2016-1"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET", "TURUN YLIOPISTO", "FRIEDRICH-SCHILLER-UNIVERSITAT JENA", "ZOOLOGISCHES FORSCHUNGSMUSEUM ALEXANDER KOENIG", "NATURHISTORISCHES MUSEUM", "PENSOFT PUBLISHERS", "Era7 Information Technologies SL", "UNIVERZITA KARLOVA", "NATURHISTORISKA RIKSMUSEET", "DECURIA AB", "SAVANTIC AB", "LUNDS UNIVERSITET"], "EU_Contribution": ["EUR 3 885 250,68"], "Project_Title": ["BIG4 - Biosystematics, Informatics and Genetics of the big 4 insect groups: training tomorrow's researchers and entrepreneurs"], "Total_Cost": ["EUR 3 885 251,22"], "Country": ["Denmark", "Finland", "Germany", "Germany", "Austria", "Bulgaria", "Spain", "Czech Republic", "Sweden", "Sweden", "Sweden", "Sweden"], "Project_ACR": ["BIG4"], "Technology_Description": "BIG4 is a global network to amalgamate the cutting edge methods of genomics, phylogenetics, informatics, taxonomy, semantic biodiversity publishing and citizen science, into highly competitive cross-disciplinary training programme for 15 ESRs with a stronghold in biosystematics. These 15 future leaders will extend the exploration of the four biggest groups of living organisms in a more forward looking way than has been attempted before. The urgent focus on the \u201cbig four\u201d insect groups, i.e. Coleoptera (beetles), Hymenoptera (wasps, ants and bees), Diptera (flies and mosquitoes), and Lepidoptera (butterflies and moths) is justified by the super abundance of this form of Life, and by the growing need by science and society to make better use of the enormous potential hidden in their biological diversity. BIG4 aims [1] to gain a robust systematic knowledge that explains the evolutionary origin, diversification, past and present distributions of living organisms, [2] to model their future dispersal and [3] to predict the traits of species that are yet unknown. Additionally, BIG4 strives for [4] implementing organismal features into engineering, medicine, agricultural or environmental solutions, the insect flight mechanics and more effective pollination to mention just a few. Such knowledge is in a particularly high demand in respect of the four biggest insects groups comprising the most important model organisms, the most dangerous pests or disease vectors, the most abundant invasive species and the most fragile entire species communities undergoing extinction due to habitat destruction. By integrating academia with the business and public sectors, BIG4 will greatly increase services and beneficial products provided by the biosystematics as a science. BIG4 will place insect mega-diversity as a powerful service for economic and societal needs such as environmental monitoring, biological control, biomedicine, or ecological farming.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2015-01-01"], "Project_ID": ["642241"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "THE UNIVERSITY OF NOTTINGHAM", "UNIVERSITY OF YORK", "WEIZMANN INSTITUTE OF SCIENCE", "UNIVERSITE D'AIX MARSEILLE", "DANMARKS TEKNISKE UNIVERSITET", "JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN", "OXFORD INSTRUMENTS INDUSTRIAL PRODUCTS LIMITED", "UNIVERSITAETSKLINIKUM FREIBURG", "Rotem Industries Ltd.", "CORTECNET"], "EU_Contribution": ["EUR 3 960 039,96"], "Project_Title": ["EUROPOL"], "Total_Cost": ["EUR 3 960 039,96"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom", "United Kingdom", "Israel", "France", "Denmark", "Germany", "United Kingdom", "Germany", "Israel", "France"], "Project_ACR": ["EUROPOL"], "Technology_Description": "NMR and MRI play unique roles in contemporary Science, from Physics, Chemistry and Biology, to clinical research and diagnosis. Despite its irreplaceable role, further progress in NMR and MRI is hampered by sensitivities that are much lower than those of alternatives such as mass-spec, or PET. The prospects of solving this problem by \u201cbigger machines\u201d are uncertain and of poor return, given the high maturity already achieved by NMR/MRI. This ETN challenges this status from an untapped perspective, combining NMR/MRI with nuclear hyperpolarization eliciting signals that surpass those currently available by up to 50,000x. Focus is placed on two particular approaches, dynamic nuclear polarization and para-hydrogen-driven polarization, exhibiting the highest potential for biophysical, metabolomic, pre-clinical and clinical research. To maximize these \u201csupersignals\u201d we assembled leading experts in the physics and engineering of magnetic resonance, in the synthetic chemistry essential for the success of these methods, in the uses of NMR to structural/cell biology, and in preclinical and clinical MRI applications. Guiding this assembling is the conception that only by teaming together key areas of expertise, can hyperpolarisation\u2019s promises be realized. In addition to fostering synergies among experts from academia and industry, EUROPOL will provide frontier training for ESRs in all the topics underlying the advancement of MR. This will include advanced physics, new instruments and forms of exploiting NMR/MRI\u2019s hyperpolarisation, biophysical NMR, screening of healthy and diseased metabolomes, expanded portfolios of substrates to be targeted by in vivo MR, ancillary in cell and system biology explorations clarifying the nature of the metabolic phenomena, and in vivo hyperpolarisation strategies in MRI. This ETN is unparalleled in scope, breadth and potential for synergies.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["642773"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["ROSKILDE UNIVERSITET", "GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER", "UPPSALA UNIVERSITET", "GROUPE SUP DE CO MONTPELLIER", "UNIVERSIDAD POMPEU FABRA", "INSTITIUID TEICNEOLAIOCHTA BHAILE ATHA CLIATH", "INSTITUTO DE GEOGRAFIA E ORDENAMENTO DO TERRITORIO DA UNIVERSIDADE DELISBOA", "UNIVERSITY OF EAST LONDON", "THE UNIVERSITY OF BIRMINGHAM", "STICHTING THE NETWORK UNIVERSITY", "STOCKHOLMS UNIVERSITET", "SWEDISH ETHIOPIAN CHAMBER OF COMMERCE", "UNIVERSITY OF STRATHCLYDE", "SYDDANSK UNIVERSITET"], "EU_Contribution": ["EUR 571 500"], "Project_Title": ["DiasporaLink"], "Total_Cost": ["EUR 571 500"], "Country": ["Denmark", "Germany", "Sweden", "France", "Spain", "Ireland", "Portugal", "United Kingdom", "United Kingdom", "Netherlands", "Sweden", "Sweden", "United Kingdom", "Denmark"], "Project_ACR": ["DiasporaLink"], "Technology_Description": "DiasporaLink is a 4-year exchange program between 24 universities and research institutes representing EU, the Americas, Africa and Australia and will investigate, evaluate and facilitate transnational diaspora entrepreneurship, TDE as driver of development and wealth creation in countries of origin and residence. ", "To": ["2019-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other", "Higher or Secondary Education Establishments", "Other", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-02-01"], "Project_ID": ["645471"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["UNIVERSITE LIBRE DE BRUXELLES", "THE UNIVERSITY OF EXETER", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "KONGSBERG MARITIME CONTROS GMBH", "STICHTING DELTARES", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "UNIVERSITY OF BRISTOL", "UPPSALA UNIVERSITET"], "EU_Contribution": ["EUR 3 112 980,61"], "Project_Title": ["Carbon Cascades from Land to Ocean in the Anthropocene"], "Total_Cost": ["EUR 3 112 980,61"], "Country": ["Belgium", "United Kingdom", "France", "Germany", "Netherlands", "Germany", "United Kingdom", "Sweden"], "Project_ACR": ["C-CASCADES"], "Technology_Description": "C-CASCADES will produce a new generation of young scientists trained to span the boundaries between disciplines and with the skill-sets required to address one of the grand research challenges of the 21st century: the role of the carbon cycle in regulating Earth\u2019s climate. Training will be embedded within and guided by the overriding science objective of the programme, to make a breakthrough in understanding the transfer of carbon between land and ocean at planetary scale and the consequences for atmospheric CO2 and climate. This will require cutting-edge research and innovation to permit characterization of the transport, transformation and ultimate fate of carbon in rivers, lakes and coastal waters and their representation in Earth System Models. This will allow a better quantification of the fluxes of greenhouse gases (primarily CO2 and CH4) exchanged with the atmosphere and their impacts on the climate system. The closely related training objective is to engage the next generation of Earth system scientists in an integrated, cutting-edge and highly relevant joint research programme. The research undertaken will capture technological innovation in sensor development; advance mechanistic understanding of the carbon transformations that occur during lateral transfer between land and ocean; embed this understanding in enhanced catchment, regional and global-scale models; and, assess quantitatively carbon transfer fluxes and carbon transformations along the land to ocean aquatic continuum at the global scale, from terrestrial ecosystems to the open ocean via rivers, lakes and coastal waters. The suite of C-CASCADES models will be progressively improved during the course of the project and evaluated against observations. These models will be applied to disentangle human impacts (e.g. land-use, river management, wastewater production, CO2, climate) on the land-to-ocean carbon cycle, for the historical period and future IPCC climate scenarios.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-01-01"], "Project_ID": ["643052"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["UNIVERSITE DE BOURGOGNE", "UNIVERSITE DE FRANCHE-COMTE", "Centre de Culture Scientifique et Technique d'Angers Terre des Sciences Association", "ASSOCIATION CAP SCIENCES-CENTRE DE CULTURE SCIENTIFIQUE TECHNIQUE ET INDUSTRIELLE BORDEAUX-AQUITAINE", "BREST'AIM SA", "UNIVERSITE DU MANS", "FONDATION PARTENARIALE DE LUNIVERSITE DE LIMOGES", "COMUNAUTE D'UNIVERSITES ET ETABLISSEMENTS UNIVERSITE DE LYON", "UNIVERSITE DE LORRAINE", "ASSOCIATION TRACES THEORIES ET REFLEXIONS SUR L APPRENDRE LA COMMUNICATION ET L EDUCATION SCIENTIFIQUES", "UNIVERSITE FEDERALE DE TOULOUSE MIDI-PYRENEES", "COMMUNAUTE D'UNIVERSITE ET D'ETABLISSEMENTS UNIVERSITE FEDERALE DE TOULOUSE MIDI-PYRENEES"], "EU_Contribution": ["EUR 421 200"], "Project_Title": ["RESEARCHER'S NIGHT IN FRANCE"], "Total_Cost": ["EUR 1 045 075"], "Country": ["France", "France", "France", "France", "France", "France", "France", "France", "France", "France", "France", "France"], "Project_ACR": ["EXPERIM"], "Technology_Description": "\"ERN has gained momentum in France. Thus, the Ministry of Research has decided to open its great \"\"Science Fair\"\" with the ERN, which is a recognition of the quality of the event and significantly develops its reputation and visibility. Therefore, we have set up a programme with distinctive visible features and a high level of consistency throughout the French territory for the 2014 and 2015 editions.", "To": ["2015-11-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-NIGHT-2014 - European Researchers' Night (NIGHT)"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Other", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2014-05-01"], "Project_ID": ["633263"], "Call_for_Proposal": ["H2020-MSCA-NIGHT-2014"]}, -{"Partners": ["ISRAEL NATIONAL MUSEUM OF SCIENCE, TECHNOLOGY AND SPACE DANIEL AND MATILDE RECANATI CENTER", "MIGAL GALILEE RESEARCH INSTITUTE LTD", "WEIZMANN INSTITUTE OF SCIENCE", "TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY", "Bloomfield Science Museum Jerusalem (BSMJ)", "THE HEBREW UNIVERSITY OF JERUSALEM", "TEL AVIV UNIVERSITY", "SAMI SHAMOON COLLEGE OF ENGINEERING(R.A.) FRIENDLY SOCIETY", "UNIVERSITY OF HAIFA", "THE OPEN UNIVERSITY*", "BAR ILAN UNIVERSITY", "ISRAEL OCEANOGRAPHIC AND LIMNOLOGICAL RESEARCH LIMITED"], "EU_Contribution": ["EUR 300 000"], "Project_Title": ["European Researchers' Night 2014 and 2015 in Israel"], "Total_Cost": ["EUR 808 050"], "Country": ["Israel", "Israel", "Israel", "Israel", "Israel", "Israel", "Israel", "Israel", "Israel", "Israel", "Israel", "Israel"], "Project_ACR": ["ERNI2014"], "Technology_Description": "Following previous eight years of successful implementation of European Researchers' Night in Israel we will have:", "To": ["2015-10-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-NIGHT-2014 - European Researchers' Night (NIGHT)"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Israel"], "Activity": ["Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2014-05-01"], "Project_ID": ["633277"], "Call_for_Proposal": ["H2020-MSCA-NIGHT-2014"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON", "FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA", "DEUTSCHES ZENTRUM FUR NEURODEGENERATIVE ERKRANKUNGEN EV", "ITA-SUOMEN YLIOPISTO", "LEIBNIZ-INSTITUT FUER NEUROBIOLOGIE", "INSTYTUT BIOLOGII DOSWIADCZALNEJ IM. M. NENCKIEGO POLSKIEJ AKADEMII NAUK", "UNIVERSITEIT ANTWERPEN", "Academisch Medisch Centrum bij de Universiteit van Amsterdam", "IPROTEOS SL", "UNIVERSITE D'AIX MARSEILLE"], "EU_Contribution": ["EUR 3 047 025,60"], "Project_Title": ["The Extracellular Matrix in Epileptogenesis"], "Total_Cost": ["EUR 3 047 025,60"], "Country": ["United Kingdom", "Italy", "Germany", "Finland", "Germany", "Poland", "Belgium", "Netherlands", "Spain", "France"], "Project_ACR": ["ECMED"], "Technology_Description": "Over 50 million people worldwide have epilepsy and 30% are resistant to our present therapies. Epilepsy, therefore, comprises a major burden to society and so there is a pressing need for new approaches to treatment. The brain extracellular matrix (ECM) plays a critical role in governing brain excitability and function. Although research into the role of the ECM in neuronal signalling and network function has advanced considerably in recent years, its full translational potential has yet to be realised. There is growing evidence for a major role of the ECM in epilepsy including the association between ECM protein mutations and epilepsy, changes in the ECM and associated proteins during the development of epilepsy and the strong association between the ECM and brain diseases associated with epilepsy including stroke, traumatic brain injury, neurodegeneration and autism. ", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Chiara Andreoli", "Tel.: +3901071781854", "Fax: +39 010 7170817", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2015-01-01"], "Project_ID": ["642881"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["STICHTING KATHOLIEKE UNIVERSITEIT", "UNIVERSITEIT UTRECHT", "UNIVERSITEIT GENT", "KING'S COLLEGE LONDON", "BIRKBECK COLLEGE - UNIVERSITY OF LONDON", "KAROLINSKA INSTITUTET", "UPPSALA UNIVERSITET", "ISTITUTO SUPERIORE DI SANITA", "UNIWERSYTET WARSZAWSKI", "VICARIOUS PERCEPTION TECHNOLOGIES BV"], "EU_Contribution": ["EUR 3 888 945,36"], "Project_Title": ["Integrated view on disruptions of early brain development"], "Total_Cost": ["EUR 3 888 945,36"], "Country": ["Netherlands", "Netherlands", "Belgium", "United Kingdom", "United Kingdom", "Sweden", "Sweden", "Italy", "Poland", "Netherlands"], "Project_ACR": ["BRAINVIEW"], "Technology_Description": "Early onset neurodevelopmental disorders such as autism spectrum disorders (ASD) and attention-deficit hyperactivity disorder (ADHD) are rather common, and affect more than 30 million children in Europe. The disorders carry a huge burden to the patients and their families and to society in general. This burden is linked to their chronic course and the absence of curative treatments. These neurodevelopmental disorders are thought to result from the disruption of normal brain development and related neurobiological mechanisms during the prenatal and early postnatal period. Recent advances in technology, infrastructure and analytic tools allow us now to identify these disruptions in brain development in the prenatal and early postnatal period, examine how this compromises the development of key social, attentional, motor and cognitive skills, and help understanding of the mechanisms that lead to neurodevelopmental disorders. This will facilitate developing new approaches to early detection, diagnosis and treatment. BRAINVIEW ETN provides a multidisciplinary and intersectoral (academia, companies, patient organizations) network environment in which cutting-edge science is combined with training young researchers in such an approach.", "To": ["2018-12-31, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["642996"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON", "GEORG-AUGUST-UNIVERSITAT GOTTINGENSTIFTUNG OFFENTLICHEN RECHTS", "CONSIGLIO NAZIONALE DELLE RICERCHE", "UNIWERSYTET WARSZAWSKI", "EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH", "ATHINA-EREVNITIKO KENTRO KAINOTOMIAS STIS TECHNOLOGIES TIS PLIROFOFORIAS, TON EPIKOLNONION KAI TIS GNOSIS", "UNIVERSITAET BIELEFELD", "UNIVERSIDADE DO MINHO", "STICHTING EIFL.NET", "UNIVERSITEIT GENT", "UNIVERSITETET I OSLO", "COAR E.V.", "STICHTING LIBER", "COOPERACION LATINOAMERICANA DE REDES AVANZADAS", "UNIVERSITEIT VAN AMSTERDAM", "EUROPEAN MOLECULAR BIOLOGY LABORATORY", "UNIVERSITAET BREMEN", "RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN", "JISC LBG", "STICHTING SURF", "KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW", "TECHNISCHE UNIVERSITEIT DELFT", "UNIVERSITAT WIEN", "INSTITUTE OF MATHEMATICS AND INFORMATICS AT THE BULGARIAN ACADEMY OF SCIENCE", "RUDER BOSKOVIC INSTITUTE", "UNIVERSITY OF CYPRUS", "VYSOKA SKOLA BANSKA - TECHNICKA UNIVERZITA OSTRAVA", "SYDDANSK UNIVERSITET", "TARTU ULIKOOL", "HELSINGIN YLIOPISTO", "CONSORTIUM UNIVERSITAIRE DE PUBLICATIONS NUMERIQUES COUPERIN", "UNIVERSITAT KONSTANZ", "ETHNIKO IDRYMA EREVNON", "DEBRECENI EGYETEM", "LANDSPITALI UNIVERSITY HOSPITAL", "THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN", "CINECA CONSORZIO INTERUNIVERSITARIO", "LATVIJAS UNIVERSITATE", "KAUNO TECHNOLOGIJOS UNIVERSITETAS", "UNIVERSITE DU LUXEMBOURG", "UNIVERSITA TA MALTA", "Sarminfo SRL", "UNIVERZITET U BEOGRADU", "CENTRUM VEDECKO TECHNICKYCH INFORMACII SLOVENSKEJ REPUBLIKY", "UNIVERZA V LJUBLJANI", "FUNDACION ESPANOLA PARA LA CIENCIA Y LA TECNOLOGIA", "KUNGLIGA BIBLIOTEKET", "UNIVERSITAT ZURICH", "IZMIR INSTITUTE OF TECHNOLOGY", "UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 13 000 000"], "Project_Title": ["Open Access Infrastructure for Research in Europe 2020"], "Total_Cost": ["EUR 13 132 500"], "Country": ["Greece", "Germany", "Italy", "Poland", "Switzerland", "Greece", "Germany", "Portugal", "Netherlands", "Belgium", "Norway", "Germany", "Netherlands", "Uruguay", "Netherlands", "Germany", "Germany", "Germany", "United Kingdom", "Netherlands", "Netherlands", "Netherlands", "Austria", "Bulgaria", "Croatia", "Cyprus", "Czech Republic", "Denmark", "Estonia", "Finland", "France", "Germany", "Greece", "Hungary", "Iceland", "Ireland", "Italy", "Latvia", "Lithuania", "Luxembourg", "Malta", "Romania", "Serbia", "Slovakia", "Slovenia", "Spain", "Sweden", "Switzerland", "Turkey", "United Kingdom"], "Project_ACR": ["OpenAIRE2020"], "Technology_Description": "OpenAIRE2020 represents a pivotal phase in the long-term effort to implement and strengthen the impact of the Open Access (OA) policies of the European Commission (EC), building on the achievements of the OpenAIRE projects. OpenAIRE2020 will expand and leverage its focus from (1) the agents and resources of scholarly communication to workflows and processes, (2) from publications to data, software, and other research outputs, and the links between them, and (3) strengthen the relationship of European OA infrastructures with other regions of the world, in particular Latin America and the U.S. Through these efforts OpenAIRE2020 will truly support and accelerate Open Science and Scholarship, of which Open Access is of fundamental importance.", "To": ["2018-06-30, ongoing project"], "Meta": [""], "Topic_s": ["EINFRA-2-2014 - e-Infrastructure for Open Access"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Greece"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Other", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other", "Other", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-01-01"], "Project_ID": ["643410"], "Call_for_Proposal": ["H2020-EINFRA-2014-1"]}, -{"Partners": ["STICHTING KATHOLIEKE UNIVERSITEIT", "UPPSALA UNIVERSITET", "BIRKBECK COLLEGE - UNIVERSITY OF LONDON", "LANCASTER UNIVERSITY", "UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA", "TWENTE MEDICAL SYSTEMS INTERNATIONAL B.V.", "ARTINIS MEDICAL SYSTEMS BV", "SMART EYE AKTIEBOLAG", "QUALISYS AB"], "EU_Contribution": ["EUR 3 685 408,56"], "Project_Title": ["Mobile Technology for Infant Social-Cognitive Neuroscience: Interdisciplinary Training Networkfor Innovative Infancy Research"], "Total_Cost": ["EUR 3 685 408,56"], "Country": ["Netherlands", "Sweden", "United Kingdom", "United Kingdom", "Italy", "Netherlands", "Netherlands", "Sweden", "Sweden"], "Project_ACR": ["MOTION"], "Technology_Description": "\"Recent international reports emphasize that the first three years of children\u2019s life have more impact on their future outcomes than any other period during life. It is therefore essential that we have a thorough understanding of early social and cognitive development. In the past, experimental research that has fed our knowledge on early development studied infants within restricted, artificial laboratory contexts. However, only by studying children who are actively engaging in natural interaction with their social and physical environment, we can acquire ecologically valid, robust information about their social and cognitive development. It is thus essential to move experimental infancy research towards more natural situations. In doing so, MOTION will train a new generation of highly-skilled experts in the field of early development.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-01-01"], "Project_ID": ["765298"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["UNIVERSITE DE PAU ET DES PAYS DE L'ADOUR", "FUNDACIO PRIVADA INSTITUT CATALA D'INVESTIGACIO QUIMICA", "TECHNISCHE UNIVERSITEIT EINDHOVEN", "UPPSALA UNIVERSITET", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "UNIVERSITAET STUTTGART", "UNIVERSITE DE NAMUR ASBL", "SOLARONIX SA", "RIVA GMBH BATTERIES", "FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA", "FUNDACIO EURECAT"], "EU_Contribution": ["EUR 3 599 025,20"], "Project_Title": ["European School on Artificial Leaf : Electrodes Devices"], "Total_Cost": ["EUR 3 599 025,20"], "Country": ["France", "Spain", "Netherlands", "Sweden", "France", "Germany", "Belgium", "Switzerland", "Germany", "Italy", "Spain"], "Project_ACR": ["eSCALED"], "Technology_Description": "Climate change resulting from accumulation of anthropogenic carbon dioxide in the atmosphere and the uncertainty in the amount of recoverable fossil fuel reserves are driving forces for the development of renewable, carbon-neutral energy technologies. Artificial photosynthesis appears to be an appealing approach for a sustainable energy generation as it produces \u201csolar fuels\u201d or commodities for chemistry in a stable and storable chemical form, from solar energy, H2O & CO2.", "To": ["2022-03-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EJD - European Joint Doctorates"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Chiara Andreoli", "Tel.: +3901071781854", "Fax: +39 010 7170817", "Research Organisations"], "From": ["2018-04-01"], "Project_ID": ["765376"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["EUROPEAN MOLECULAR BIOLOGY LABORATORY", "STAZIONE ZOOLOGICA ANTON DOHRN", "UNIVERSITETET I BERGEN", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSITY COLLEGE LONDON", "THE UNIVERSITY OF EXETER", "RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG", "UPPSALA UNIVERSITET", "MUSEUM FUR NATURKUNDE - LEIBNIZ-INSTITUT FUR EVOLUTIONS- UND BIODIVERSITATSFORSCHUNG AN DER HUMBOLDT-UNIVERSITAT ZU BERLIN", "GENOMIX4LIFE SRL", "BLACKTRACE HOLDINGS LIMITED"], "EU_Contribution": ["EUR 3 818 591,07"], "Project_Title": ["Animal evolution from a cell type perspective: multidisciplinary training in single-cell genomics, evo-devo and in science outreach"], "Total_Cost": ["EUR 3 818 591,07"], "Country": ["Germany", "Italy", "Norway", "France", "United Kingdom", "United Kingdom", "Germany", "Sweden", "Germany", "Italy", "United Kingdom"], "Project_ACR": ["EvoCELL"], "Technology_Description": "One of the first events in the evolution of multicellular animals was the differentiation of cells into distinct types with different roles. Starting from their most simple multicellular ancestors, the cells that compose animal bodies have become increasingly diverse; each cell type distinguished by the unique set of genes it expresses. This increase in diversity of cell types over evolutionary time is recapitulated in the process of development during which a single undifferentiated cell - the fertilised egg - divides and its progeny differentiate into the countless cell types of the adult body. Currently we do not even know how many distinct cell types animals posses, how new cell types arise in evolution, how many are in common between different animal groups and how many unique cell types have evolved in different lineages. Our aim in EvoCELL is to lay the foundation for a new branch of evo-devo focussing on cell types. We will study these fundamental questions in animal evolution and development using a new technology - single cell sequencing - which we will for the first time employ outside of lab models to sample the great diversity of animal phyla. Europe is home to world-leading expertise in evo-devo and single-cell genomics, but research and training efforts are as yet uncoordinated and their potential for synergy underexplored. EvoCELL will harness and expand this European excellence by training a new generation of multidisciplinary scientists skilled in exploring the vast breadth of animal differentiation. We will jointly sample data from all major animal lineages, richly represented in the biodiversity of European waters, and develop new tools for comparative analyses, through which we will together pioneer three branches of cell evo-devo: evolution of stem cells; emergence of animal life cycles, and the stunning diversity of neural cell types.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-01-01"], "Project_ID": ["766053"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI SASSARI"], "EU_Contribution": ["EUR 168 277,20"], "Project_Title": ["Urbanization in China's South-western Borderlands. The case of Jinghong, Xiguangbanna"], "Total_Cost": ["EUR 168 277,20"], "Country": ["Italy"], "Project_ACR": ["URBAN_CHINA"], "Technology_Description": "This interdisciplinary research project aims to study urbanization in China\u2019s non-metropolitan and non-industrial ethnic-diverse border regions under post-socialism. Literature on urbanization in China focuses mainly on traditional large metropolitan or industrial cities in the center with Han majority population, and examines either the structural or the subjective features of urban development. The complex dynamics of urbanization and power relations in the new cities in the periphery remain understudied. The project fills this knowledge gap, by exploring how urbanization intersects with tourism growth and in-migration and affects ethnic relations in Jinghong, a fast-growing city in China\u2019s south-western borderlands. In Jinghong, the Han, China\u2019s ethnic majority, have become the city\u2019s drivers of urban and economic development, competing over land, resources and political power with long-term Dai/Tai minority ethnic residents. Unconventionally drawing on methods of Anthropology, Urban Planning, Architecture, Urban Geography, and Sociology, this pioneering project aims at producing a theoretically and empirically innovative analysis that combines structural, socio-economic, and political examination with an investigation of subjective and experiential aspects of urbanization, highlighting conflicts, mindsets, and prejudices in the day-to-day urban interactions between Han majority and ethnic minority citizens and the state. ", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["748961"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["SWANSEA UNIVERSITY", "ALFRED-WEGENER-INSTITUT HELMHOLTZ-ZENTRUM FUR POLAR- UND MEERESFORSCHUNG", "KOBENHAVNS UNIVERSITET", "HELLENIC CENTRE FOR MARINE RESEARCH", "UNIVERSITE LIBRE DE BRUXELLES", "STICHTING DELTARES", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6"], "EU_Contribution": ["EUR 2 882 898,72"], "Project_Title": ["Bringing the paradigm for marine pelagic production into the 21st century: incorporating mixotrophy into mainstream marine research"], "Total_Cost": ["EUR 2 882 898,72"], "Country": ["United Kingdom", "Germany", "Denmark", "Greece", "Belgium", "Netherlands", "Spain", "France"], "Project_ACR": ["MixITiN"], "Technology_Description": "The conceptual basis upon which management tools for our oceans, seas and coasts have operated are out-of-date. MixITiN will train an innovative team of early stage researchers (ESRs) to develop and deploy new methodologies for researching, monitoring and managing our marine environment according to the recently revised paradigm for marine pelagic production. Current management tools and policies operate within a paradigm that builds on a simple division functioning at the base of the food chain leading to fisheries, between \u201dplant-like\u201d phytoplankton and their main consumers, the microzooplankton. Applicants of the research programme MixITiN have shown that this plant-animal paradigm represents at the least a gross simplification, if not a falsehood. The revised paradigm recognises that most phytoplankton and half the microzooplankton combine plant-like photosynthesis with animal-like consumer activity within the one cell. This form of nutrition, \u201cmixotrophy\u201d, supports the growth of organisms important for food chains and biogeochemical cycles removing atmospheric CO2; they are also causative agents of harmful algal blooms. In consequence of this revised paradigm, laboratory and field research approaches, management policies and allied computer modelling tools, are arguably no longer fit for purpose. MixITiN brings together European world-class research and training centres from 9 different countries, with skillsets from molecular biology, physiology and computer modelling, to marine and coastal zone management, public and media engagement. MixITiN will train ESRs in multinational and multidisciplinary centres of excellence, with intersectoral engagement enabling them to gain employment in various sectors such as consultancy, government, academic, or allied industries. The synergy of training approaches provided to the ESRs will raise their capabilities and progress science beyond the current state-of-the-art to enable improved management of marine resources.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["766327"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["UNIVERSITY OF GLASGOW"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Perpendicular Magnetic Anisotropy: from Topological Defects to Reconfigurable Magnetic Devices"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["MAGTOPRECON"], "Technology_Description": "The present project aims to explore and control the behavior of magnetic topological defects in weak Perpendicular Magnetic Anisotropy materials by creating different hard/soft magnetic nanostructures with reconfigurable properties.Both, static and dynamic behaviors will be exploded and finally, a demonstration device will be prepared: a reconfigurable magnonic crystal with potential applications in information and communication technologies.Weak perpendicular magnetic anisotropy materials present fascinating magnetic stripe domain arrangements sharing phenomenology with other self-organized systems.These magnetization configurations can be understood as a 2D magnetic crystal.Topological defects within the stripes\u2019 lattice condition and drive the magnetization processes of the system being their study a key factor for both, fundamental and technological goals. One of the objectives of the project is to go a step further in the study of magnetic topological defects in these systems. We want to characterize, with unprecedented detail, the behavior of magnetization textures and control their evolution by locally tuning the film properties.Not only static properties will be analyzed, but also the dynamics. It will allow to observe interesting spin wave phenomena, and ultimately, to identify and excite the dynamic modes of topological defects.To achieve this, a unique combination of ferromagnetic resonance with Lorentz Transmission Electron Microscopy will be used, with guidance from micromagnetic simulations.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["746958"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAT WIEN"], "EU_Contribution": ["EUR 178 156,80"], "Project_Title": ["Mass-waste modelling across scales"], "Total_Cost": ["EUR 178 156,80"], "Country": ["Austria"], "Project_ACR": ["MAWAMOSCA"], "Technology_Description": "\"Mass-waste events not only cause geomorphological changes on our planet but they are often natural hazards, causing significant economic impact or seriously endangering human lives. Sufficiently understanding and predicting them is an important task both for the scientific community as well as to the decision-making bodies and community leaders all around the world. The importance of the topic is also emphasized in the EU Horizon 2020 third pillar \"\"Societal Challenges\"\".", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["743713"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF LEEDS"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["From an environmental to a resource regime? Institutional innovation for the management of Tourism and Marine Protected Areas within the Antarctic Treaty governance"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["POLARGOV"], "Technology_Description": "The Antarctica Treaty presents one of the most intriguing environmental regimes to international relations: its institutionalisation has intensified as much as the Treaty has been able to keep controversy away from its governance. The current arrangement postpones, outsources or builds an ambiguous guidance towards any subject which might undermine its consensual foundation. But are these solutions able to keep the Antarctic Treaty's resilience as a regime? Antarctic history shows that expectations towards resource activities within the region has triggered challenges to this framework. Nevertheless, Antarctic Tourism and Marine Protected Areas (MPAs) are current activities respectively outsourced and avoided by the Treaty, despite of their direct impact on the Antarctic Treaty operation. Therefore, this proposal aims to contribute towards the Antarctic Treaty governance, proposing institutional innovations which would support the Treaty to manage complex, multilevel and controversial activities. Based on stakeholders' assessment of the Antarctic Treaty governance on Tourism and MPAs, hybrid strategies and institutional interplay will be developed and presented for discussion to these actors. The project expects to directly contribute for the Treaty\u2019s resilience as a regime, to increase public awareness on Antarctic matters through open access information and engaging outreach strategies, and to develop a European perspective on Antarctic politics. A vibrant research environment, expertise on environmental and resource regimes, and training for the researcher will be offered by the University of Leeds, enabling the development of the proposal and the boosting of the researcher\u2019s career as an academic and expert on Antarctic politics. Furthermore, the researcher's experience in Antarctic treaties and networking, as well as her expertise in academic research, will result into publications and partnerships, establishing a European research legacy for Antarctic politics", "To": ["2019-09-05, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-06"], "Project_ID": ["750745"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF LEICESTER", "PRESIDENT AND FELLOWS OF HARVARD COLLEGE"], "EU_Contribution": ["EUR 269 857,80"], "Project_Title": ["Spirits of Displacement and Diaspora"], "Total_Cost": ["EUR 269 857,80"], "Country": ["United Kingdom", "United States"], "Project_ACR": ["SDD"], "Technology_Description": "Spirit possession cults puzzle Western observers, particularly when they appear in supposedly secular urban environments. Muslim migrants from North Africa, seeking to establish new lives in Southern Europe, have to negotiate the continuity of such ritual practices with the constraints and expectations imposed on them by their new social contexts. But the legitimacy of these cults is contested also in their homeland, where they face increasing pressures by religious fundamentalism. Space and its organization, especially in urban settings, play an important part in these disputes. In Morocco, spirits are thought to reside in particular places, such as tombs, sanctuaries, or street corners. How do possession cults continue to be practiced when spirits\u2019 spaces of residence have to be abandoned or undergo demolition? This research compares the continuities and ruptures in cult performances as the spaces that host them are affected by both forced displacement and voluntary diasporic migration. I will observe the resettlement of a slum in Casablanca, and compare it with two Southern European neighborhoods where Moroccan practitioners of spirit cults struggle to maintain their specific version of Islam in multicultural, post-colonial and post-secular urban settings, exposed to disruptive processes such as gentrification. By applying an ethnographic methodology to comparative urbanism, I aim to shed light on how different spatial transformations affect ritual performances that are meant to protect communities from social disintegration. I argue that different urban policies on both sides of the Mediterranean mutually reinforce, resulting in an overall transformation of cultural practices in transnational communities. Examining how migrants adapt localized ritual practices such as spirit possession cults to increasingly transient urban settings, furthers our understanding of the spatial and cultural dimensions that enable or prevent integration.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["752547"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["TECHNISCHE UNIVERSITAET MUENCHEN", "TECHNISCHE UNIVERSITAET MUENCHEN"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Modular Platform for Controlled Ion Beam Generation"], "Total_Cost": ["EUR 150 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["SoftBeam"], "Technology_Description": "Countless sophisticated macroscopic products rely on innovative materials with unique features, designed with nanoscale precision. To harness the variety of functionalities provided by biomolecules and other complex molecular species as the key ingredient for the design of prospective advanced nanosystems and materials, a current technological gap must be closed: the lack of a universal method capable to handle fragile molecules under vacuum conditions without compromising their integrity. With the present project we aim to introduce a versatile and powerful platform based on innovative methodological advances to overcome this obstacle. The envisioned technology is designated CIB (controlled ion beam) and will allow the generation of ultrapure ion beams from any solvable substance in a fully controlled manner using a cost-effective, marketable setup. The novel instrumentation capitalizes on achievements within the ERC project 'MolArt' and will be suitable for highly sophisticated deposition processes for nanofabrication and nanotechnology, while furnishing at the same time a general module integrable in analytical mass spectrometry (MS/ Proteomics). SoftBeam, the prototype instrument to be accomplished within this PoC project is our pilot application where CIB is firstly realized and validated. With this technology an entire new class of sensitive substances can be routinely processed in a size-selective manner. Boosted flux intensities reduce processing time and fully controllable energy of the molecules results in a highly increased reproducibility, cleanliness and homogeneity of molecular beams generated. The modular platform is adaptable to various disciplines and has the potential to become a standard tool in the nanotechnology and analytical (bio)chemistry community.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["780907"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Using global marine metagenomics to understand MERcury microbial associated processes: finding a CURE for mercury contaminated environments"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["MER-CURE"], "Technology_Description": "Millions of people are exposed to harmful levels of the potent neurotoxin mercury (Hg), concretely to the organic form methylmercury (MeHg) that bio-accumulates in organisms and biomagnifies in marine food webs. Understanding Hg transformations in the ocean is critical because commercial fish are mainly marine species. While it is well known that both MeHg formation and degradation are genetically mediated by prokaryotes, there are still sizable gaps in the fundamental understanding of the organisms and mechanisms involved in Hg transformations in the environment and therefore a clear lack of available techniques for Hg removal based on the action of these genes. MER-CURE aims at filling this gap by providing the first Hg reference gene catalogue at a global ocean scale and by quantifying the individual and/or combined effect of the activity of these genes in a pilot Hg removal system. MER-CURE develops a novel and multidisciplinary methodological approach by merging omics and Hg stable isotope tracer technologies for studying the biogeochemistry and detoxification of Hg. Concretely, the fellow will take advantage of the available sequenced metagenomes and metatranscriptomes and isolates from the Global Ocean Circunnavigation Expedition Malaspina. She will carry out laboratory conducted experiments to elucidate the capacity of different marine isolates to detoxify Hg-contaminated sediments. MER-CURE will contribute to advance knowledge by identifying \u201cwhere\u201d and \u201cwhich\u201d prokaryotes in the ocean are involved in Hg cycling and to produce readily applicable results that can in the future help municipality and private industries. MER-CURE is committed to knowledge sharing and to engage the public into the action. The incorporation of metagenomic and metatranscriptomics analyses in Dr. Bravo toolbox will lead the fellow to master a rather unique combination of chemistry, biology, experimental approaches, public engagement, and knowledge sharing and communication skills.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2018-09-01"], "Project_ID": ["749645"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAET HAMBURG", "UPPSALA UNIVERSITET", "TECHNOLOGIKO PANEPISTIMIO KYPROU", "UNIVERSITY OF GLASGOW", "STIFTUNG PREUSSISCHER KULTURBESITZ", "AARHUS UNIVERSITET", "ASHOKA UK"], "EU_Contribution": ["EUR 3 406 970,52"], "Project_Title": ["PARTICIPATORY MEMORY PRACTICES. Concepts, strategies, and media infrastructures for envisioning socially inclusive potential futures of European Societies through culture"], "Total_Cost": ["EUR 3 406 970,52"], "Country": ["Germany", "Sweden", "Cyprus", "United Kingdom", "Germany", "Denmark", "United Kingdom"], "Project_ACR": ["POEM"], "Technology_Description": "Diverging forces across European societies, most visible in both the contemporary nationalist movements and Islamist radicalization, demand a socially inclusive public memory. Its implementation calls for new strategies, practices, and infrastructures for staging and empowering membership and contribution of people from diverse social and cultural backgrounds for past and future development in Europe. To reach this goal, research needs to develop a comprehensive understanding on concepts, practices, and media infrastructures that facilitate the partaking of people from various backgrounds in the heritage building work of memory institutions (libraries, archives, and museums). The POEM-ETN will provide this comprehensive knowledge by studying in practice theoretical approaches on how connectivities are built by 1) institutions, 2) people and groups, and 3) media infrastructures for a socially inclusive, participatory heritage work and what facilitates or hinders collaboration. Therefore, a new generation of professionals will be trained through an innovative training programme and supervised by peer networks of transdisciplinary knowledge to act as change agents, brokers, and problem solvers in this contested field of heritage work. The comprehensive transdisciplinary composition of the consortium involving universities, memory institutions, civil society organisations, and SMEs from public and private sectors will therefore provide the POEM fellows with transdisciplinary knowledge on cultural and social analysis as well as on transferrable skills with respect to the changing socio-technical, organisational, legal, economic, and ethical issues to address future challenges for participatory memory work.", "To": ["2022-03-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Other"], "From": ["2018-04-01"], "Project_ID": ["764859"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE"], "EU_Contribution": ["EUR 1 499 390"], "Project_Title": ["Computational Molecular Materials Discovery"], "Total_Cost": ["EUR 1 499 390"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["CoMMaD"], "Technology_Description": "The objective of the project is to develop a computational approach to accelerate the discovery of molecular materials. These materials will include porous molecules, small organic molecules and macromolecular polymers, which have application as a result of either their porosity or optoelectronic properties. The applications that will be targeted include in molecular separations, sensing, (photo)catalysis and photovoltaics. To achieve my aims, I will screen libraries of building blocks through a combination of techniques including evolutionary algorithms and machine learning. Through the application of cheminformatics algorithms, I will target the most promising libraries, assess synthetic diversity and accessibility and analyse structure-property relationships. I will develop software that will predict the (macro)molecular structures and properties; the molecular property screening calculations will include void characterisation, binding energies, diffusion barriers, local assembly, charge transport and energy level assessment. A consideration of synthetic accessibility at every stage will be central to my approach, which will ensure the realisation of our predicted targets. I have several synthetic collaborators who can provide pathways to synthetic realisation. Improved materials in this field have the potential to either reduce our energy needs or provide renewable energy, helping the EU meet the targets of the 2030 Energy Strategy.", "To": ["2023-03-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-04-01"], "Project_ID": ["758370"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["van der Waals Heterostructures for Innovative PhotoCATalysts"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["WHIPCAT"], "Technology_Description": "Engineering of atomic (two-dimensional (2D)) layered solids is receiving immense attention from the scientific community due to the possibilities of tuning the optical, mechanical, electronic and electrochemical properties by combinatorial stacking of different atomic layers as novel candidates for energy and environmental applications. Van der Waals solids (vdW) of Semiconducting Transition Metal Dichalcogenides (STMD) have been largely investigating 2D materials, where its physico-chemical properties show a drastic contrast in comparison to its bulk. Visible light absorption, indirect to direct bandgap transition, layer dependent photoluminescence (PL) etc. are some of the stark contrasts in atomically layered STMD vdW crystals from bulk, making them unique for photocatalysis and photo-(electro) catalysis (PEC) applications. In this work, Fabrication of variety of novel heterogeneous STMD clusters with combinations of different transition metal (TM): Mo, W and V and chalcogenide (C): S, Se and Te by cluster beam deposition will be carried out for the efficient visible light photocatalysis and PEC applications. Size and edge termination dependent photophysical properties will be investigated and further implemented for the efficient visible light PEC from this kind of vdW solids. A dual-target, magnetron-sputtering gas condensation cluster source will be used to deposit pristine combinatorial stacked nanoclusters of TMs and Cs onto various substrates. The photocatatlytic reaction kinetics will be estimated from the visible light absorption, Raman/PL spectroscopy and photoconductivity studies. Further PEC activity towards HER/oxygen reduction reaction (ORR)/oxygen evolution reaction (OER) from the STMD vdW nanoclusters will be evaluated from linear sweep voltammetry and cyclic voltammetry in acidic and basic electrolytes in dark and light conditions.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["750929"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6", "UPPSALA UNIVERSITET", "INSTITUT MINES-TELECOM", "KUNGLIGA TEKNISKA HOEGSKOLAN", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "INESC ID - INSTITUTO DE ENGENHARIADE SISTEMAS E COMPUTADORES, INVESTIGACAO E DESENVOLVIMENTO EM LISBOA", "JACOBS UNIVERSITY BREMEN GGMBH", "SOFTBANK ROBOTICS EUROPE"], "EU_Contribution": ["EUR 3 890 624,76"], "Project_Title": ["Advancing intuitive human-machine interaction with human-like social capabilities for education in schools"], "Total_Cost": ["EUR 3 890 624,76"], "Country": ["France", "Sweden", "France", "Sweden", "Switzerland", "Portugal", "Germany", "France"], "Project_ACR": ["ANIMATAS"], "Technology_Description": "ANIMATAS will establish a leading European Training Network (ETN) devoted to the development of a new generation of creative and critical research leaders and innovators who have a skill-set tailored for the creation of social capabilities necessary for realising step changes in the development of intuitive human-machine interaction (HMI) in educational settings. This will be achieved through (1) a transnational network of universities and industrial partners that will supervise and deliver specialized training for early stage researchers (ESRs), and (2) the cross-fertilization of state-of-the-art methods from the domains of social robotics, embodied virtual characters, social and educational sciences in order to facilitate the development of skills necessary to design machines capable of engaging in intuitive sustained encounters with teachers and children. The ETN will ensure an integrative approach to the development of new capabilities with a view to their impact on whole system performance in terms of the complete HMI loop. This will be done by building industry\u2013guided showcases that integrate the social capabilities developed by the ESRs. The participation of industrial partners will support the translation of new academic results to the market-place and a better transfer of knowledge between different sectors. The exposure of the non- academic sector to the ESRs has a great market potential that our industrial partners aim to capitalize upon in terms of recruiting young talents after the end of the project and adopting ANIMATAS\u2019 advances in intuitive HMI for future product lines. This will greatly benefit the ESRs, which will be provided with new career perspectives in the social robotics and ed-tech industries. The ETN will strengthen Europe\u2019s capacity in research and innovation by nurturing a new generation of highly skilled ESRs with an entrepreneurial mind-set and an understanding of intuitive HMI and potential products in these emerging markets.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-01-01"], "Project_ID": ["765955"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["UNIVERZITA KARLOVA", "UNIVERZITA KARLOVA"], "EU_Contribution": ["EUR 924 375"], "Project_Title": ["Accuracy and precision for molecular solids"], "Total_Cost": ["EUR 924 375"], "Country": ["Czech Republic", "Czech Republic"], "Project_ACR": ["APES"], "Technology_Description": "The description of high pressure phases or polymorphism of molecular solids represents a significant scientific challenge both for experiment and theory. Theoretical methods that are currently used struggle to describe the tiny energy differences between different phases. It is the aim of this project to develop a scheme that would allow accurate and reliable predictions of the binding energies of molecular solids and of the energy differences between different phases.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Czech Republic"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["759721"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["KOC UNIVERSITY", "KOC UNIVERSITY"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Computational Simulations of MOFs for Gas Separations"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Turkey", "Turkey"], "Project_ACR": ["COSMOS"], "Technology_Description": "Metal organic frameworks (MOFs) are recently considered as new fascinating nanoporous materials. MOFs have very large surface areas, high porosities, various pore sizes/shapes, chemical functionalities and good thermal/chemical stabilities. These properties make MOFs highly promising for gas separation applications. Thousands of MOFs have been synthesized in the last decade. The large number of available MOFs creates excellent opportunities to develop energy-efficient gas separation technologies. On the other hand, it is very challenging to identify the best materials for each gas separation of interest. Considering the continuous rapid increase in the number of synthesized materials, it is practically not possible to test each MOF using purely experimental manners. Highly accurate computational methods are required to identify the most promising MOFs to direct experimental efforts, time and resources to those materials. In this project, I will build a complete MOF library and use molecular simulations to assess adsorption and diffusion properties of gas mixtures in MOFs. Results of simulations will be used to predict adsorbent and membrane properties of MOFs for scientifically and technologically important gas separation processes such as CO2/CH4 (natural gas purification), CO2/N2 (flue gas separation), CO2/H2, CH4/H2 and N2/H2 (hydrogen recovery). I will obtain the fundamental, atomic-level insights into the common features of the top-performing MOFs and establish structure-performance relations. These relations will be used as guidelines to computationally design new MOFs with outstanding separation performances for CO2 capture and H2 recovery. These new MOFs will be finally synthesized in the lab scale and tested as adsorbents and membranes under practical operating conditions for each gas separation of interest. Combining a multi-stage computational approach with experiments, this project will lead to novel, efficient gas separation technologies based on MOFs.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Turkey"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["756489"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITEIT TWENTE", "UNIVERSITEIT TWENTE"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Advancing cell based therapies by supporting implant survival"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["ENABLE"], "Technology_Description": "Tissue engineering aims at the creation of living implants to replace, repair, or regenerate damaged, diseased, or aged tissues, which holds tremendous possibilities to both extend our lives and improve our quality of life. During the last decades, our ability to create small tissues to heal small animals e.g. mice and rats has taken a breath taking leap. However, we have relentlessly struggled to create viable tissues of human-relevant sizes. Creating solid large tissues imposes lethal nutrient diffusion limitations, which causes the living implant to suffer from starvation, loss of function, and inevitable failure. ", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["759425"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITAT DES SAARLANDES", "UNIVERSITAT DES SAARLANDES"], "EU_Contribution": ["EUR 2 460 000"], "Project_Title": ["Inpainting-based Compression of Visual Data"], "Total_Cost": ["EUR 2 460 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["INCOVID"], "Technology_Description": "Generating huge amounts of visual data, be it images or videos, has never been easier than today. This creates a growing demand for lossy codecs (coders and decoders) that produce visually convincing results also for very high compression rates. Popular transform-based codecs such as JPEG and JPEG 2000 have reached a state where one cannot expect significant improvements anymore. To go beyond their limitations, fundamentally different ideas are needed.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Peter Druschel", "Tel.: +4968193039100", "Fax: +4968193036029", "Higher or Secondary Education Establishments", "Corinna Hahn", "Tel.: +49 681 95 92 3362", "Fax: +49 681 95 92 3370", "Higher or Secondary Education Establishments", "Corinna Hahn", "Tel.: +49 681 95 92 3362", "Fax: +49 681 95 92 3370"], "From": ["2017-10-01"], "Project_ID": ["741215"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITAET BREMEN", "UNIVERSITAET BREMEN"], "EU_Contribution": ["EUR 1 486 250"], "Project_Title": ["The Legacy of Colonialism: Origins and Outcomes of Social Protection"], "Total_Cost": ["EUR 1 486 250"], "Country": ["Germany", "Germany"], "Project_ACR": ["COLSOC"], "Technology_Description": "Social protection has been one of the most popular instruments for promoting human development across the globe. However, the great majority of the global population is not or only partly covered by social protection. Especially in developing countries it is often the very poorest who do not receive essential social benefits. This is highly problematic since inclusive social protection is assumed to be a key factor for national productivity, global economic growth and domestic stability. Social protection in many developing countries can be traced back to colonial times. Surprisingly, the influence of colonialism has been a blind spot for existing theories and empirical studies of comparative social policy. In this project it is argued that the colonial legacy in terms of the imperial strategy of the colonial power, the characteristics of the colonized society and the interplay between the two is crucial in explaining early and contemporary social protection. Hence, the main objective of this project is to systematically understand how colonialism has shaped the remarkable differences in social protection and its postcolonial outcomes. Given the paucity of our information and understanding of social protection in former colonies, an interactive dataset on the characteristics, origins and outcomes of social protection will be developed including comprehensive data on former British and French colonies from the beginning of the 20th century until today. The dataset will be backed by insights derived from four case studies elucidating the causal mechanisms between the colonial legacy and early and contemporary social protection. The proposed project breaks new ground by improving our understanding of why social protection in some developing countries has led to more inclusive societies while reinforcing existing inequalities in others. Such an understanding is a prerequisite in informing the contemporary struggle against poverty and social inequality.", "To": ["2023-03-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-04-01"], "Project_ID": ["755129"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON", "UNIVERSITY COLLEGE LONDON", "PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE"], "EU_Contribution": ["EUR 2 499 908"], "Project_Title": ["Smartphones, Smart Ageing and mHealth"], "Total_Cost": ["EUR 2 549 908"], "Country": ["United Kingdom", "United Kingdom", "Chile"], "Project_ACR": ["SmartPhoneSmartAging"], "Technology_Description": "This project will investigate fundamental changes in people\u2019s relationship to age and health associated with the global rise of the smartphone. The aim is to combine an intellectual challenge in understanding the contemporary nature of age and the impact of new media, with an applied challenge to use this knowledge to help make mHealth a more effective intervention. ", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["740472"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["HELMHOLTZ ZENTRUM FUR OZEANFORSCHUNG KIEL", "HELMHOLTZ ZENTRUM FUR OZEANFORSCHUNG KIEL"], "EU_Contribution": ["EUR 1 499 989"], "Project_Title": ["Male pregnancy \u2013 Unravelling the coevolution of parental investment and immune defence"], "Total_Cost": ["EUR 1 499 989"], "Country": ["Germany", "Germany"], "Project_ACR": ["MALEPREG"], "Technology_Description": "The question of how sex roles and parental investment have evolved belongs to the most controversial unresolved issues in evolutionary biology. The costliest form of reproduction regarding parental investment is viviparity. Its independent evolution in most vertebrate groups has required drastic morphological and genomic reorganisations in the sex bearing the young. Yet our knowledge is heavily biased towards mammals, where changes in the immune system and microbial composition are associated with pregnancy and placentation. Which factors have caused the selection and accompanied evolution of viviparity in other vertebrates remains severely understudied. ", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-03-01"], "Project_ID": ["755659"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS", "STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS"], "EU_Contribution": ["EUR 1 950 775"], "Project_Title": ["Single-molecule visualization of transcription dynamics to understand regulatory mechanisms of transcriptional bursting and its effects on cellular fitness"], "Total_Cost": ["EUR 1 950 775"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["BURSTREG"], "Technology_Description": "Transcription in single cells is a stochastic process that arises from the random collision of molecules, resulting in heterogeneity in gene expression in cell populations. This heterogeneity in gene expression influences cell fate decisions and disease progression. Interestingly, gene expression variability is not the same for every gene: noise can vary by several orders of magnitude across transcriptomes. The reason for this transcript-specific behavior is that genes are not transcribed in a continuous fashion, but can show transcriptional bursting, with periods of gene activity followed by periods of inactivity. The noisiness of a gene can be tuned by changing the duration and the rate of switching between periods of activity and inactivity. Even though transcriptional bursting is conserved from bacteria to yeast to human cells, the origin and regulators of bursting remain largely unknown. Here, I will use cutting-edge single-molecule RNA imaging techniques to directly observe and measure transcriptional bursting in living yeast cells. First, bursting properties will be quantified at different endogenous and mutated genes to evaluate the contribution of cis-regulatory promoter elements on bursting. Second, the role of trans-regulatory complexes will be characterized by dynamic depletion or gene-specific targeting of transcription regulatory proteins and observing changes in RNA synthesis in real-time. Third, I will develop a new technology to visualize the binding dynamics of single transcription factor molecules at the transcription site, so that the stability of upstream regulatory factors and the RNA output can directly be compared in the same cell. Finally, I will examine the phenotypic effect of different bursting patterns on organismal fitness. Overall, these approaches will reveal how bursting is regulated at the molecular level and how different bursting patterns affect the heterogeneity and fitness of the organism.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["755695"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["TECHNISCHE UNIVERSITAET WIEN", "TECHNISCHE UNIVERSITAET WIEN"], "EU_Contribution": ["EUR 1 997 202,49"], "Project_Title": ["Tuneable Catalyst Surfaces for Heterogeneous Catalysis \u2013 Electrochemical Switching of Selectivity and Activity"], "Total_Cost": ["EUR 1 997 202,49"], "Country": ["Austria", "Austria"], "Project_ACR": ["TUCAS"], "Technology_Description": "In heterogeneous catalysis surfaces decorated with uniformly dispersed, catalytically highly active particles are a key requirement for excellent performance. One of the main tasks in catalysis research is the continuous improvement or development of catalytically active materials.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["755744"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["ALFRED-WEGENER-INSTITUT HELMHOLTZ-ZENTRUM FUR POLAR- UND MEERESFORSCHUNG", "ALFRED-WEGENER-INSTITUT HELMHOLTZ-ZENTRUM FUR POLAR- UND MEERESFORSCHUNG"], "EU_Contribution": ["EUR 1 499 082"], "Project_Title": ["Space-time structure of climate change"], "Total_Cost": ["EUR 1 499 082"], "Country": ["Germany", "Germany"], "Project_ACR": ["SPACE"], "Technology_Description": "I will determine and use the space-time structure of climate change from years to millennia to test climate models, fundamentally improve the understanding of climate variability and provide a stronger basis for the quantitative use of paleoclimate records.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["716092"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["SCUOLA NORMALE SUPERIORE"], "EU_Contribution": ["EUR 180 277,20"], "Project_Title": ["Civil society organizations and the politics of long-term care reform: coalitions and multiple inequalities"], "Total_Cost": ["EUR 180 277,20"], "Country": ["Italy"], "Project_ACR": ["AGenDA"], "Technology_Description": "Population ageing and gender inequality are cross-cutting political and societal challenges facing Europe. AGenDA meets this challenges by implementing novel and interdisciplinary state-of the-art research on the interaction between multiple intersecting inequalities in Long-Term Care (LTC) reforms. It focuses on the impact of civil society organizations (CSOs) mobilizing around gender, age and disability in reform coalitions in Italy and Spain. Through research and public engagement, AGenDA\u2019s strives to promote inclusive equality in LTC systems, thereby contributing to meet Horizon 2020 challenges \u201cHealth, demographic change and wellbeing\u201d and \u201cInclusive, Innovative and Reflective societies\u201d. By engaging civil society, it promotes participation and effectiveness of social actors in decision-making processes as highlighted in Europe 2020 strategy. By focusing on countries which are laggards in the development of LTC and gender equality policies, AGenDA produces and disseminates knowledge on the social and political obstacles that impede the development of fair and inclusive LTC systems, thereby strengthening integration and cohesion within the European Union. In line with MSCA objectives, AGenDA includes a comprehensive training plan to enhance the future career opportunities and inter-sectoral employability of the researcher. These objectives will be achieved through excellent training-through-research, an academic secondment developing new interdisciplinary and methodological competencies and a non-academic secondment providing access to policy networks and on-the-job-training in outreach and public engagement. The ambitious dissemination and communication plan aims at enhancing the international visibility of the project, promoting knowledge-transfer between all actors involved, and producing wider impact on EU institutions, policy-makers, CSOs, academics and the general public.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["746168"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UPPSALA UNIVERSITET", "UPPSALA UNIVERSITET"], "EU_Contribution": ["EUR 1 467 500"], "Project_Title": ["Jigsaw puzzles at atomic resolution: Computational design of GPCR drugs from fragments"], "Total_Cost": ["EUR 1 467 500"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["FRAGMENT2DRUG"], "Technology_Description": "Despite technological advances, industry struggles to develop new pharmaceuticals and therefore novel strategies for drug discovery are urgently needed. G protein-coupled receptors (GPCRs) play important roles in numerous physiological processes and are important drug targets for neurological diseases. My research focuses on modelling of GPCR-ligand interactions at the atomic level, with the goal to increase knowledge of receptor function and develop new methods for drug discovery. Breakthroughs in GPCR structural biology and access to sensitive screening assays provide opportunities to utilize fragment-based lead discovery (FBLD), a powerful approach for drug design. The objective of the project is to create a computational platform for FBLD, with a vision to transform the early drug discovery process for GPCRs. As structural information for these targets is limited, predictive models of receptor-fragment complexes will be crucial for the successful use of FBLD. In this project, computational structure-based methods for discovery of fragment ligands and further optimization of these to potent leads will be developed. These techniques will be applied to address two difficult problems in drug discovery. The first of these is to design ligands of peptide-binding GPCRs that have been challenging for existing methods. One of the promises of FBLD is to provide access to difficult targets, which will be explored by combining molecular docking and biophysical screening against peptide-GPCRs to identify novel lead candidates. A second challenge is that efficient treatment of neurological disorders often requires modulation of multiple targets, which also will be the focus of the project.", "To": ["2022-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["715052"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["CONSIGLIO NAZIONALE DELLE RICERCHE", "CONSIGLIO NAZIONALE DELLE RICERCHE", "DHITECH DISTRETTO TECNOLOGICO HIGH-TECH SCARL"], "EU_Contribution": ["EUR 149 406"], "Project_Title": ["Electro-optical polariton router"], "Total_Cost": ["EUR 149 406"], "Country": ["Italy", "Italy", "Italy"], "Project_ACR": ["ElecOpteR"], "Technology_Description": "In this proposal we plan to bring to a development stage TRL 3 an electro-optical device working at room temperature and based on polaritons (an hybrid photon-exciton particle) made of 2D perovskites and of an optical surface mode in a Distributed Bragg Reflector waveguide. Such a device could lead to extremely compact and ultrafast electro-optical modulators that can be fully integrated in a microchip to allow for fast signal communications between each peripheral component of a processor. As a matter of fact one of the major bottlenecks in processing speed is caused by retardations and dissipations in the interconnections between the CPU and the memory elements as well as other interconnect functions. Conversion of the electrical signal into an optical one can allow for faster and more efficient processing. Our prototype can allow for switching and routing of guided optical beams via electrical signals using the intrinsic nonlinearities of the hybrid photon-exciton states.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-10-01"], "Project_ID": ["780757"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["UNIVERSITEIT GENT", "UNIVERSITEIT GENT"], "EU_Contribution": ["EUR 1 391 250"], "Project_Title": ["Chip Scale Electrically Powered Optical Frequency Combs"], "Total_Cost": ["EUR 1 391 250"], "Country": ["Belgium", "Belgium"], "Project_ACR": ["ELECTRIC"], "Technology_Description": "In ELECTRIC, I will integrate electrically powered optical frequency combs on mass manufacturable silicon chips. This will allow for making use of all the advantageous properties of these light sources in real-life situations.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["759483"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN", "CIIMAR - Centro Interdisciplinar de Investiga\u00e7\u00e3o Marinha e Ambiental", "EUROPEAN MOLECULAR BIOLOGY LABORATORY", "UNIVERSITE LIBRE DE BRUXELLES", "UNIVERSITETET I BERGEN", "NATIONAL UNIVERSITY OF IRELAND GALWAY", "UNIVERSITY OF BRISTOL", "HITS GGMBH", "GENERALDIREKTION DER STAATLICHE NATURWISSENSCHAFTLICHEN SAMMLUNGEN BAYERNS", "INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE", "UNIVERSITY COLLEGE LONDON", "FACULTY OF SCIENCE UNIVERSITY OF ZAGREB", "Era7 Information Technologies SL", "PENSOFT PUBLISHERS"], "EU_Contribution": ["EUR 3 810 685,32"], "Project_Title": ["Comparative genomics of non-model invertebrates"], "Total_Cost": ["EUR 3 810 685,32"], "Country": ["Germany", "Portugal", "Germany", "Belgium", "Norway", "Ireland", "United Kingdom", "Germany", "Germany", "France", "United Kingdom", "Croatia", "Spain", "Bulgaria"], "Project_ACR": ["IGNITE"], "Technology_Description": "Invertebrates, i.e., animals without a backbone, represent 95% of animal diversity on earth but are a surprisingly underexplored reservoir of genetic resources. The content and architecture of their genomes remain poorly known or understood, but such knowledge is needed to fully appreciate their evolutionary, ecological and socio--economic importance, as well as to leverage the benefits they can provide to human well-being, for example as a source for novel drugs and biomimetic materials. Europe is home to significant world-leading expertise in invertebrate genomics but research and training efforts are as yet uncoordinated. IGNITE will bundle this European excellence to train a new generation of scientists skilled in all aspects of invertebrate genomics. We will considerably enhance animal genome knowledge by generating and analysing novel data from undersampled invertebrate lineages and developing innovative new tools for high-quality genome assembly and analysis. Well-trained genomicists are in increasing demand in universities, research institutions, as well as in software, biomedical, and pharmaceutical companies. Through their excellent interdisciplinary and intersectoral training spanning from biology and geobiology to bioinformatics and computer science, our graduates will be in a prime position to take up leadership roles in both academia and industry in order to drive the complex changes needed to advance sustainability of our knowledge-based society and economy.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-01-01"], "Project_ID": ["764840"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 142 324"], "Project_Title": ["Device for much improved performance portable power"], "Total_Cost": ["EUR 142 324"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["Portapower"], "Technology_Description": "\"Portable power (~1-20 W) for small electronic devices is a high value added market. Batteries are the most convenient power devices but have relatively low energy capacity per unit mass and also slow recharge times. Micro-solid oxide fuel (micro-SOFC) cells are much better on both counts but currently operate at too high of a temperature (>500\u00b0C). This project will reduce that temperature by 200\u00b0C in prototype test devices. It will do this by exploiting much improved materials in the micro-SOFC, these materials having been discovered and developed in an ERC AdG grant held by the PI. The project will involve prototype device fabrication and testing in conjunction with a small start-up company, the ultimate aim being to take the technology forward to market.\"", "To": ["2019-11-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-06-01"], "Project_ID": ["779444"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 149 997"], "Project_Title": ["Functional magnetic materials for biomedical applications"], "Total_Cost": ["EUR 149 997"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["BioMagMat"], "Technology_Description": "A range of new medical therapies and diagnostics based on magnetic nanomaterials have recently been proposed. These include cancer therapies, stem cell therapies, microfluidic diagnostic devices and immunoassays. However, very few biotechnology magnetic nanomaterials are currently available commercially; most investigators fabricate their own. This is a serious limitation to the development of this emerging area within nanomedicine. This proposal aims to transfer a number of magnetic nanomaterials from the University physics laboratory where they were developed as part of an ERC AdG grant into an existing small company where they can then be made available to researchers across the world on a commercial basis.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["779822"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "CENTRO EUROPEO DI FORMAZIONE E RICERCA IN INGEGNERIA SISMICA", "JRC -JOINT RESEARCH CENTRE- EUROPEAN COMMISSION", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "LABORATORIO NACIONAL DE ENGENHARIA CIVIL", "PANEPISTIMIO PATRON", "UNIVERSITY OF BRISTOL", "PUBLIC SCIENTIFIC INSTITUTE-INSTITUTE OF EARTHQUAKE ENGINEERING AND ENGINEERING SEISMOLOGY SS CYRIL AND METHODIUS UNIVERSITY SKOPJE IZIIS", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "UNIVERSITA DEGLI STUDI DI TRENTO", "UNIVERSIDADE DO PORTO", "UNIVERSIDAD POLITECNICA DE MADRID", "BOGAZICI UNIVERSITESI", "ARISTOTELIO PANEPISTIMIO THESSALONIKIS", "HELMHOLTZ ZENTRUM POTSDAM DEUTSCHESGEOFORSCHUNGSZENTRUM GFZ", "KONINKLIJK NEDERLANDS METEOROLOGISCH INSTITUUT-KNMI", "INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA PAMANTULUI", "NATIONAL OBSERVATORY OF ATHENS", "UPPSALA UNIVERSITET", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "NATURAL ENVIRONMENT RESEARCH COUNCIL", "Euro-Mediterranean Seismological Centre", "UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II.", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "AMRA - ANALISI E MONITORAGGIO DEL RISCHIO AMBIENTALE SCARL", "STIFTELSEN NORSAR", "Instytut Geofizyki Polskiej Akademii Nauk", "ISTITUTO NAZIONALE DI GEOFISICA E VULCANOLOGIA", "INSTITUTO SUPERIOR TECNICO", "BUREAU DE RECHERCHES GEOLOGIQUES ET MINIERES", "UNIVERSITETET I BERGEN"], "EU_Contribution": ["EUR 10 000 000"], "Project_Title": ["Seismology and Earthquake Engineering Research Infrastructure Alliance for Europe"], "Total_Cost": ["EUR 11 090 779,02"], "Country": ["Switzerland", "Italy", "Belgium", "France", "Portugal", "Greece", "United Kingdom", "Former Yugoslav Republic of Macedonia", "United Kingdom", "Italy", "Portugal", "Spain", "Turkey", "Greece", "Germany", "Netherlands", "Romania", "Greece", "Sweden", "Spain", "United Kingdom", "France", "Italy", "France", "Italy", "Norway", "Poland", "Italy", "Portugal", "France", "Norway"], "Project_ACR": ["SERA"], "Technology_Description": "SERA is the \"Seismology and Earthquake Engineering Research Infrastructure Alliance for Europe\", responding to the priorities identified in the call INFRAIA-01-2016-2017 Research Infrastructure for Earthquake Hazard.", "To": ["2020-04-30, ongoing project"], "Meta": [""], "Topic_s": ["INFRAIA-01-2016-2017 - Integrating Activities for Advanced Communities"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Other", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["730900"], "Call_for_Proposal": ["H2020-INFRAIA-2016-1"]}, -{"Partners": ["TEL AVIV UNIVERSITY", "TEL AVIV UNIVERSITY"], "EU_Contribution": ["EUR 1 496 875"], "Project_Title": ["Engineering T cells and B cells for Immunotherapy using V(D)J recombination"], "Total_Cost": ["EUR 1 496 875"], "Country": ["Israel", "Israel"], "Project_ACR": ["VDJtargeting"], "Technology_Description": "T cell engineering has shown clinical success mainly in haematological cancers, but scaling up is challenging due to reliance on ex vivo manipulations. In addition, B cell engineering has not shown therapeutic efficacy to date. Here, we propose a novel immunotherapy approach, allowing safe and efficient engineering of B cells and T cells, both ex vivo and in vivo. We will use adeno associated vectors (AAV) to integrate chimeric antigen receptor (CAR) or T cell receptor (TCR) genes into loci coding TCR chains and to integrate antibody (Ab) genes into loci coding Ab chains. Previously, we used AAV facilitated gene targeting in vivo to ameliorate genetic diseases in mice. For lymphocytes we develop \u201cVDJ targeting\u201d: A promoterless receptor/Ab gene flanked by recognition signal sequences (RSS) will be inserted into the endogenous locus by the recombination activating gene (RAG) complex during V(D)J recombination. Only developing lymphocytes, expressing RAG, will incorporate the receptor/Ab gene, which will thus be expressed in potent na\u00efve cells from the strong endogenous promoter. Targeted developing cells are subjected to negative selection, thus reducing risk of adverse autoimmunity. Lack of promoter reduces spurious expression and oncogenic risk upon rare off-target integration. Targeting endogenous loci may allow allelic exclusion. In B cells it may allow utilizing the endogenous constant region to express a B cell receptor and, upon activation, a secreted Ab. Activation may be accompanied by proliferation and affinity maturation, including somatic hypermutation and class switching, to allow a potent immune response, memory retention and diminished antigenic escape. Where controlled autoimmunity is desired, we will engineer B cells to inducibly secret an auto-Ab. We will demonstrate efficacy in cancer and autoimmune disease models implanted with lymphocytes that we engineered while ex vivo differentiated and in mice injected with vectors for in vivo VDJ targeting.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["759296"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET", "KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 1 497 260"], "Project_Title": ["Signals from the Surface Snow: Post-Depositional Processes Controlling the Ice Core IsotopicFingerprint"], "Total_Cost": ["EUR 1 497 260"], "Country": ["Denmark", "Denmark"], "Project_ACR": ["SNOWISO"], "Technology_Description": "For the past 50 years, our use of ice core records as climate archives has relied on the fundamental assumption that the isotopic composition of precipitation deposited on the ice sheet surface determines the ice core water isotopic composition. Since the isotopic composition in precipitation is assumed to be governed by the state of the climate this has made ice core isotope records one of the most important proxies for reconstructing the past climate.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["759526"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITEIT GENT", "UNIVERSITEIT GENT"], "EU_Contribution": ["EUR 1 498 469"], "Project_Title": ["Microclimatic buffering of plant responses to macroclimate warming in temperate forests"], "Total_Cost": ["EUR 1 498 469"], "Country": ["Belgium", "Belgium"], "Project_ACR": ["FORMICA"], "Technology_Description": "Recent global warming is acting across ecosystems and threatening biodiversity. Yet, due to slow responses, many biological communities are lagging behind warming of the macroclimate (the climate of a large geographic region). The buffering of microclimates near the ground measured in localized areas, arising from terrain features such as vegetation and topography, can explain why many species are lagging behind macroclimate warming. However, almost all studies ignore the effects of microclimatic buffering and key uncertainties still exist about this mechanism. Microclimates are particularly evident in forests, where understorey habitats are buffered by overstorey trees. In temperate forests, the understorey contains the vast majority of plant diversity and plays an essential role in driving ecosystem processes.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["757833"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITEIT GENT", "UNIVERSITEIT GENT"], "EU_Contribution": ["EUR 1 476 250"], "Project_Title": ["Everyday Writing in Graeco-Roman and Late Antique Egypt (I - VIII AD). A Socio-Semiotic Study of Communicative Variation"], "Total_Cost": ["EUR 1 476 250"], "Country": ["Belgium", "Belgium"], "Project_ACR": ["EVWRIT"], "Technology_Description": "This five-year project aims to generate a paradigm shift in the understanding of Graeco-Roman and Late Antique communication. Non-literary, \u2018documentary\u2019 texts from Ancient Egypt such as letters, petitions and contracts have provided and continue to provide a key witness for our knowledge of the administration, education, economy, etc. of Ancient Egypt. This project argues that since documentary texts represent originals, their external characteristics should also be brought into the interpretation: elements such as handwriting, linguistic register or writing material transmit indirect social messages concerning hierarchy, status, and power relations, and can therefore be considered \u2018semiotic resources\u2019. The project\u2019s driving hypothesis is that communicative variation \u2013 variation that is functionally insignificant but socially significant (e.g. there are ~ there\u2019s ~ it\u2019s a lot of people) \u2013 enables the expression of social meaning. The main aim of this project is to analyse the nature of this communicative variation. To this end, a multidisciplinary team of six researchers (one PI, one post-doc, and four PhD\u2019s) will apply recent insights form socio-semiotic and socio-linguistic theory to a corpus of Graeco-Roman and Late Antique documentary texts (I \u2013 VIII AD) by means of a three-level approach: (i) an open-access database of annotated documentary texts will be created; (ii) the \u2018semiotic potential\u2019 of the different semiotic resources that play a role in documentary writing will be analysed; (iii) the interrelationships between the different semiotic resources will be studied. The project will have a significant scientific impact: (i) it will be the first to offer a holistic perspective towards the \u2018meaning\u2019 of documentary texts; (ii) the digital tool will open up new ways to investigate Ancient texts; (iii) it will make an important contribution to current socio-semiotic and socio-linguistic research; (iv) it will provide new insights about humans as social beings.", "To": ["2023-05-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-06-01"], "Project_ID": ["756487"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Waves of history in the South Pacific: A gene-culture coevolutionary approach"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["Waves"], "Technology_Description": "Modern humans have colonized every possible ecological niche, with the latest expansions being those into the remote islands of the South Pacific. This success has been underpinned both by genetic adaptations to new ecological conditions and by an ever-accumulating store of technological and cultural knowledge gained through social learning. Our dual inheritance systems of genetics and culture interact in unique and unexpected ways, making human history vastly more difficult to infer than for any other species. The emerging field of gene-culture coevolution promises to provide a cohesive framework for modeling the interplay of genes and culture, and will revolutionize our understanding of human historical processes. The Waves project will build the tools necessary to establish gene-culture coevolution in the genomic-era, extending cutting-edge population genetic techniques \u2013 including spatial simulation \u2013 and allowing the natural integration of data from across genomics, archaeogenetics, archaeology and historical linguistics. We will focus on the South Pacific, a region whose past demography remains largely unresolved. While the population history of this region is relatively short it appears extremely complex, comprising not only multiple waves of colonization but also the existence of wide and ongoing interaction spheres through which both seafaring peoples and their cultures maintained long-distance connections. By generating comprehensive new ancient and present-day genome-wide datasets across Near and Remote Oceania \u2013 and analyzing them alongside historical linguistic and cultural data \u2013 the Waves project will create the first unified gene-culture coevolutionary history of the South Pacific.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2018-01-01"], "Project_ID": ["758967"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 359 688"], "Project_Title": ["The challenging quest for low-mass dark structures"], "Total_Cost": ["EUR 1 359 688"], "Country": ["Germany", "Germany"], "Project_ACR": ["LEDA"], "Technology_Description": "Using strong gravitational lensing, I will constrain with my unique modelling technique and acquired knowledge the properties of dark matter and potentially revise the current standard paradigm for the formation of all structures which is at the core of modern cosmology and galaxy formation theories. ", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2018-02-01"], "Project_ID": ["758853"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["TEL AVIV UNIVERSITY", "TEL AVIV UNIVERSITY"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Robustness and specialization among hormone transporters: Redundant and unique roles"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Israel", "Israel"], "Project_ACR": ["RobustHormoneTrans"], "Technology_Description": "\"Plant growth and development is governed by finely tuned, highly regulated hormone gradients. Impressive progress has been made in understanding plant hormone signaling, but knowledge on the mechanisms underlying their precise localization at the tissue and subcellular levels is still very limited. We and others have recently identified the first bona fide GA transporters in plants as members of the NPF protein family. Proteins from the ABC family were shown to transport the CK, ABA, and auxin hormones. Although these studies suggested specialized functions for members of these large protein families, progress in understanding their level of specialization has been limited by the scarcity of loss-of-function phenotypes, masked by the highly redundant plant genome. The goal of this proposal is to reveal the robust and specialized function of the NPF and ABC plant hormone transporter families. The project places key technological challenges that require multi-disciplinary expertise to examine how plants balance redundancy and specialization to tightly regulate hormone localization. Broad and targeted transportome screens using multi-targeted artificial miRNAs and CRISPR technology in Arabidopsis and tomato, respectively, are designed to unveil novel plant hormone transporters, with an emphasis on subcellular localized transporters and the missing GA exporters. Specialization and robustness of candidate transporters will be evaluated by integrating in vitro transport assays with in vivo growth and development experiments. I believe that the proposed \"\"redundant-free\"\" populations will lead to new paradigms in plant genetics and would explain how gene families have developed robustness together with unique and diverse specialization. Importantly, our combined genetic and organelle-specific hormone profiling approaches will establish fundamental new concepts regarding plant hormone localization, activity, and specificity at the subcellular level.\"", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["757683"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UPPSALA UNIVERSITET"], "EU_Contribution": ["EUR 1 753 287,89"], "Project_Title": ["Firms and Their Networks"], "Total_Cost": ["EUR 1 753 287,89"], "Country": ["France", "France", "Sweden"], "Project_ACR": ["FIRMNET"], "Technology_Description": "There is mounting evidence that firms are becoming more fragmented; production is less often made \u201cin-house\u201d. Firms buy inputs from abroad. Tasks are often split in parts. Some are offshored, others are subcontracted. Hence, firms buy services from other, local or international, firms. But they also supply inputs to other firms. Technical change, the internet, and globalization, all facilitate this transformation. ", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["741467"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["DANMARKS TEKNISKE UNIVERSITET", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "UNIVERSITY COLLEGE LONDON", "MEDIZINISCHE UNIVERSITAET WIEN", "ICOMETRIX NV", "PHILIPS MEDICAL SYSTEMS NEDERLAND BV", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.", "REGION HOVEDSTADEN", "TECHNISCHE UNIVERSITAET MUENCHEN", "TECHNISCHE UNIVERSITEIT EINDHOVEN"], "EU_Contribution": ["EUR 3 938 655,60"], "Project_Title": ["Translational Brain Imaging Training Network"], "Total_Cost": ["EUR 3 938 655,60"], "Country": ["Denmark", "Switzerland", "United Kingdom", "Austria", "Belgium", "Netherlands", "Germany", "Denmark", "Germany", "Netherlands"], "Project_ACR": ["TRABIT"], "Technology_Description": "\"Brain diseases account for one third of the overall disease burden in Europe, and their already significant cost to society is expected to further escalate as a result of the aging European population. In recent decades, medical imaging techniques such as computed tomography, ultrasound, and especially magnetic resonance imaging have gained a central role in the clinical management of disorders of the brain. A fundamental bottleneck in translating the wealth of information contained in medical images into optimized patient care is the lack of computational tools to reliably and accurately analyze the available images. Combined with the sheer volume of data acquired on a daily basis, the current dearth of computational tools means that most of the relevant information contained in today's clinical brain scans simply remains unused.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["765148"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH", "EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["TOF PET With Strip SiPMs"], "Total_Cost": ["EUR 150 000"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["TWIST"], "Technology_Description": "TWIST will build detector modules for PET scanners that offer high sensitivity together with precise position and time resolution. TWIST will deliver high-resolution PET images with low background using a lower dosage of radio-tracer. The breakthrough is obtained due to the successful development of the new Strip Silicon PhotoMultiplier (SSiPM) within the ERC TICAL project.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["780151"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["QUEEN MARY UNIVERSITY OF LONDON", "UNIVERSITA DEGLI STUDI DI TRIESTE", "ILLYCAFFE S.P.A", "CENTER ODLICNOSTI ZA BIOSENZORIKO,INSTRUMENTACIJO IN PROCESNO KONTROLO ZAVOD", "BIOREALIS SRO"], "EU_Contribution": ["EUR 1 335 986,28"], "Project_Title": ["Imprinted Polymers as Coffee Sensors"], "Total_Cost": ["EUR 1 335 986,28"], "Country": ["United Kingdom", "Italy", "Italy", "Slovenia", "Slovakia"], "Project_ACR": ["IPCOS"], "Technology_Description": "Food quality is a global key priority area where technological advances in terms of quality control have been limited. The aim of the IPCOS Network is to bring innovation to the field of food quality by offering an international, interdisciplinary and intersectorial doctoral training programme that will target the development of chemical sensors, using the molecular imprinting technology, for application in the coffee industry, focusing on three main targets: chlorogenic acids, cafestol and kaurene terpenes, caffeine and its metabolites, all of which have been shown to have an impact on consumers\u2019 health. This project brings together 2 academic teams, 1 large international company, 1 SME and one non-profit research centre of excellent, supported by 4 associated teams, with a very multidisciplinary and multisectorial expertise. The IPCOS training program will require ESRs to work 50% of their time in industry, providing them with a set of unique scientific and transferable skills that will match both public and private sector needs, together with a strong development of innovation and entrepreneurship ethos, therefore considerably enhancing their career perspectives. All researchers will aim to achieve a doctoral degree at the end of their training. As a result of the close collaborative links, IPCOS will strengthen the innovation capacity of universities/research institutes to commercially exploit their research and enhance the research potential and competitiveness of European companies and SMEs.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-EID - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-EID)"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["642014"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["FORSCHUNGSZENTRUM JULICH GMBH", "FORSCHUNGSZENTRUM JULICH GMBH"], "EU_Contribution": ["EUR 1 482 672"], "Project_Title": ["Impact and interaction of prophage elements in bacterial host strains of biotechnological relevance"], "Total_Cost": ["EUR 1 482 672"], "Country": ["Germany", "Germany"], "Project_ACR": ["PRO_PHAGE"], "Technology_Description": "Phages, viruses that prey on bacteria, are the most abundant and diverse inhabitants of the Earth. Temperate bacteriophages are able to integrate into the host genome and maintain as prophages a long-term association with their host. Illustrated by the development of mutually beneficial traits, this close interaction between host and virus has significantly shaped bacterial evolution. However, the immense genetic resources of phage genomes still remain almost unexplored. For the transition to a sustainable bioeconomy, we strongly depend on microbes as hosts for the production of value-added compounds. PRO_PHAGE will exploit recent advances in next-generation sequencing (NGS), single-cell analysis, and high-throughput (HT) phenotyping to evaluate the impact of phage elements on host fitness and to use this knowledge for the improvement of future metabolic engineering approaches.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["757563"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION", "FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Cell-to-cell variability during symmetry breaking in organoid development"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["SymBreakOrganoid"], "Technology_Description": "Cell-to-cell variability is an inherent property of populations of cells. As a starting point for symmetry breaking events, it is also an essential building block for self-organised pattern forming systems. Nonetheless, the sources and roles of cell-to-cell variability in symmetry-breaking events during collective cell behavior await a quantitative and mechanistic understanding. To obtain these insights, we will use a model system of intestinal organoids, which recapitulates most of the processes of morphogenesis and patterning observed in intestinal tissue. In this system, the symmetry-breaking event is observed when, despite all single cells in a growing organoid are exposed to uniform environments, only a fraction of cells acquires specific cell fates, generating asymmetric structures such as crypts and villi. This project aims to uncover the extent, sources, and consequences of cell heterogeneity. To this end, we will use advanced multiplexed imaging of intestinal stem cells in 3D organoid development to monitor quantitatively the behaviour of each single cell in the system. Initially, we will identify potential sources of cell-to-cell variability, such as the microenvironment or the cell cycle. Next, we will create models to identify predictors of symmetry breaking and patterning. In parallel, we will determine the extent of cellular heterogeneity by single-cell RNA sequencing during organoid formation. Finally, we will test if cellular heterogeneity is necessary and sufficient to induce symmetry-breaking of intestinal organoids by experimentally inducing and perturbing cell-to-cell variability. Thus, this research proposal will address a major question in developmental biology and collective cell behavior, namely how single cells exposed to a uniform growth-promoting environment generate asymmetric structures. Moreover, it will unravel how local interactions between single cells give rise to emergent, self-organized patterns.", "To": ["2023-09-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-10-01"], "Project_ID": ["758617"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Majorana neutrino discovery strategy with CMS"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["MajorNet"], "Technology_Description": "The Large Hadron Collider at CERN is successfully operating at a record-breaking energy and is expected to deliver an enormous dataset of 300/fb of proton-proton collisions in the next 6 years. I propose to take advantage of both the unprecedented collision energy and the large number of events to be recorded in order to search for signs of new particles which could uncover the nature of dark matter, provide an explanation for the matter-antimatter asymmetry of the universe or answer questions about the origin of neutrino masses. To achieve this, I will build on my expertise devising and organizing new physics searches with leptons and will establish and lead a new multi-signature research programme at the CMS experiment. This programme will exploit both the intensity and energy frontiers opening up at the LHC and can be further expanded at the high-luminosity LHC (HL-LHC). Since the masses and couplings of the new particles are unconstrained, my proposed search strategy will be such that a wide mass range will be covered also encompassing many orders of magnitude in the coupling strength.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["758316"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["KING'S COLLEGE LONDON", "KING'S COLLEGE LONDON"], "EU_Contribution": ["EUR 1 499 999"], "Project_Title": ["Dynamical Redesign of Biomolecular Networks"], "Total_Cost": ["EUR 1 499 999"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["BioNet"], "Technology_Description": "Enzymes created by Nature are still more selective and can be orders of magnitude more efficient than man-made catalysts, in spite of recent advances in the design of de novo catalysts and in enzyme redesign. The optimal engineering of either small molecular or of complex biological catalysts requires both (i) accurate quantitative computational methods capable of a priori assessing catalytic efficiency, and (ii) molecular design principles and corresponding algorithms to achieve, understand and control biomolecular catalytic function and mechanisms. Presently, the computational design of biocatalysts is challenging due to the need for accurate yet computationally-intensive quantum mechanical calculations of bond formation and cleavage, as well as to the requirement for proper statistical sampling over very many degrees of freedom. Pioneering enhanced sampling and analysis methods have been developed to address crucial challenges bridging the gap between the available simulation length and the biologically relevant timescales. However, biased simulations do not generally permit the direct calculation of kinetic information. Recently, I and others pioneered simulation tools that can enable not only accurate calculations of free energies, but also of the intrinsic molecular kinetics and the underlying reaction mechanisms as well. I propose to develop more robust, automatic, and system-tailored sampling algorithms that are optimal in each case. I will use our kinetics-based methods to develop a novel theoretical framework to address catalytic efficiency and to establish molecular design principles to key design problems for new bio-inspired nanocatalysts, and to identify and characterize small molecule modulators of enzyme activity. This is a highly interdisciplinary project that will enable fundamental advances in molecular simulations and will unveil the physical principles that will lead to design and control of catalysis with Nature-like efficiency.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["757850"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.", "UNIVERSITY OF SOUTHAMPTON", "UNIVERSITE JEAN MONNET SAINT-ETIENNE", "ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON", "OPEN DATA INSTITUTE LBG"], "EU_Contribution": ["EUR 3 885 922,44"], "Project_Title": ["Answering Questions using Web Data"], "Total_Cost": ["EUR 3 885 922,44"], "Country": ["Germany", "Germany", "United Kingdom", "France", "Greece", "United Kingdom"], "Project_ACR": ["WDAqua"], "Technology_Description": "The H2020 work programme aims at increasing citizens\u2019 participation in the digital society and making infrastructures \u201csmart\u201d. These processes are increasingly data-driven. Our central motivation is that sharing, connecting, managing, analysing and understanding data on the Web will enable better services for citizens, communities and industry. However, turning web data into successful services for the public and private sector requires skilled web and data scientists, and it still requires further research. WDAqua aims at advancing the state of the art by intertwining training, research and innovation efforts, centered around one service: data-driven question answering.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other"], "From": ["2015-01-01"], "Project_ID": ["642795"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["AARHUS UNIVERSITET", "AARHUS UNIVERSITET"], "EU_Contribution": ["EUR 1 499 848"], "Project_Title": ["Cholesterol and Sugar Uptake Mechanisms"], "Total_Cost": ["EUR 1 499 848"], "Country": ["Denmark", "Denmark"], "Project_ACR": ["CSUMECH"], "Technology_Description": "Cardiovascular disease, diabetes and cancer have a dramatic impact on modern society, and in great part are related to uptake of cholesterol and sugar. We still know surprisingly little about the molecular details of the processes that goes on in this essential part of human basic metabolism. This application addresses cholesterol and sugar transport and aim to elucidate the molecular mechanism of cholesterol and sugar uptake in humans. It moves the frontiers of the field by shifting the focus to in vitro work allowing hitherto untried structural and biochemical experiments to be performed.", "To": ["2020-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-07-01"], "Project_ID": ["637372"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["Institute of Science and Technology Austria", "Institute of Science and Technology Austria"], "EU_Contribution": ["EUR 1 446 542"], "Project_Title": ["Circuits of Visual Attention"], "Total_Cost": ["EUR 1 446 542"], "Country": ["Austria", "Austria"], "Project_ACR": ["Daphne"], "Technology_Description": "The evolutionary arms race has optimized and shaped the way animals attend to relevant sensory stimuli in an ever-changing environment. This is a complex task, because the vast majority of sensory experiences are not relevant. In humans, attentional disorders are a serious public health concern because of its high prevalence, but its causes are mostly unknown. In this proposal, I will explore the neuronal mechanisms used by the nervous system to attend visual cues to enable appropriate behaviors. ", "To": ["2022-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["756502"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Coexistence on the boundary of chaos"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["COEXIST"], "Technology_Description": "This project is an exploration of the essence of chaos. Chaos and chaotic systems are by their very nature unpredictable. Paradoxically, the manner in which systems transition into chaotic regimes is highly structured and rigid. This contradiction can be explained mathematically through an elegant process called renormalization. Renormalization is like a microscope which can be used to observe the shape of fractals that appear on the boundary of chaos. One aspect of the structure of chaos is that such fractals on a large scale may look nothing like each other, but as the magnification factor on the microscope is increased they look more and more alike. This is expressed by saying that renormalization converges. Convergence of renormalization has been a consistent theme since the very inception of chaos theory, thus it was believed that the structure of chaos was thoroughly understood. In an unexpected twist, the applicant recently made the groundbreaking discovery that there are natural systems for which the renormalization sometimes is convergent and at other times degenerate. This reveals that the structure of chaos in fact is much more intricate than was previously imagined.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["743959"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITEIT GENT", "UNIVERSITEIT GENT"], "EU_Contribution": ["EUR 149 609"], "Project_Title": ["Miniature on-chip Raman spectrometer for personal volatile organic compound (VOC) monitoring"], "Total_Cost": ["EUR 149 609"], "Country": ["Belgium", "Belgium"], "Project_ACR": ["MIRASPEC"], "Technology_Description": "We aspire to build the smallest and most lightweight Raman spectrometer in the world, with a target size of 5x10x1 mm3 and a weight of only 0.1 g. The innovation builds on the combination of three key results of the ERC Advanced Grant project InSpectra (2011-2017): 1. Demonstration of Nanophotonic waveguide Enhanced Raman Spectroscopy (NERS); 2. Demonstration of a novel on-chip Fourier Transform Spectrometer (FTS); 3. Demonstration of the integration of III-V light sources on a silicon platform through bonding or transfer printing technologies. By using a standard CMOS process toolset for fabricating the Raman spectrometer, a cost-effective and high yield product can be guaranteed with a price level at least an order of magnitude lower than current commercial systems. The exceptional form factor of the spectrometer will generate a rich variety of innovative applications of Raman spectroscopy. A spectrometer this small can be implanted, incorporated in smartphones or smartwatches and fits into textiles, drones etc. In this ERC PoC project, we will build this miniature spectrometer and use it for the target application of detecting volatile organic compounds (VOC) for personal safety monitoring, both at work and at home.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["780718"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET", "KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 1 499 695"], "Project_Title": ["Manifesting the Simplicity of Scattering Amplitudes"], "Total_Cost": ["EUR 1 499 695"], "Country": ["Denmark", "Denmark"], "Project_ACR": ["AMPLITUDES"], "Technology_Description": "I propose a program of research that may forever change the way that we understand and use quantum field theory to make predictions for experiment. This will be achieved through the advancement of new, constructive frameworks to determine and represent scattering amplitudes in perturbation theory in terms that depend only on observable quantities, make manifest (all) the symmetries of the theory, and which can be efficiently evaluated while minimally spoiling the underlying simplicity of predictions. My research has already led to the discovery and development of several approaches of this kind. ", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["757978"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["WEIZMANN INSTITUTE OF SCIENCE", "WEIZMANN INSTITUTE OF SCIENCE"], "EU_Contribution": ["EUR 1 493 803"], "Project_Title": ["Realizable Advanced Cryptography"], "Total_Cost": ["EUR 1 493 803"], "Country": ["Israel", "Israel"], "Project_ACR": ["REACT"], "Technology_Description": "In a free society, there is persistent tension between utility and privacy. Citizens have the basic right to keep their personal information private. However, sometimes keeping our data private could significantly reduce our ability to use this data to benefit ourselves or society. This tension is multiplied many times over in our modern data driven society, where data is utilized using remote algorithms. ", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["756482"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["WEIZMANN INSTITUTE OF SCIENCE", "WEIZMANN INSTITUTE OF SCIENCE"], "EU_Contribution": ["EUR 1 442 360"], "Project_Title": ["A Theory for Understanding, Designing, and Training Deep Learning Systems"], "Total_Cost": ["EUR 1 442 360"], "Country": ["Israel", "Israel"], "Project_ACR": ["THUNDEEP"], "Technology_Description": "The rise of deep learning, in the form of artificial neural networks, has been the most dramatic and important development in machine learning over the past decade. Much more than a merely academic topic, deep learning is currently being widely adopted in industry, placed inside commercial products, and is expected to play a key role in anticipated technological leaps such as autonomous driving and general-purpose artificial intelligence. However, our scientific understanding of deep learning is woefully incomplete. Most methods to design and train these systems are based on rules-of-thumb and heuristics, and there is a drastic theory-practice gap in our understanding of why these systems work in practice. We believe this poses a significant risk to the long-term health of the field, as well as an obstacle to widening the applicability of deep learning beyond what has been achieved with current methods.", "To": ["2023-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["754705"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["TECHNISCHE UNIVERSITEIT EINDHOVEN", "TECHNISCHE UNIVERSITEIT EINDHOVEN"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["New chemical building blocks for de-icing and anti-icing of car windows"], "Total_Cost": ["EUR 150 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["PRicelessCOAT"], "Technology_Description": "Ice accretion of car windshields is a road safety concern in fall and wintertime as frost impairs the vision of drivers that do not sufficiently de-ice their car windshields, which may cause serious road accidents. Windshield washer fluids are crucially important for rapid car windshield de-icing which is most efficient through a combination of thermal, mechanical, and chemical action; i.e., local heating, scraping, and the application of appropriate windshield washer fluids. At present, windshield washer fluids rely solely on colligative antifreezes. The current formulations are (highly) flammable which requires precautionary measures in stores and cars, and the ethanol used is derived from sugarcane which is a valuable food resource. The challenge is to develop a commercially viable solution to replace these colligative antifreezes by an innovative screenwash formulation that is highly effective, but not flammable, does not present a health risk, and does not use food resources. In \u2018PRicelessCOAT\u2019 scientists will develop new biocompatible and biodegradable chemical building blocks for de-icing and anti-icing of car windows.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["780160"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["UNIVERSITY OF YORK"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Heterogeneous Effects of Fiscal Consolidation on Firms' Balance Sheets"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["FLASH"], "Technology_Description": "The global financial crisis and slow ensuing recovery have put severe strains on the fiscal positions of many OECD countries, raising serious concerns about fiscal sustainability, especially in the Euro Area. The challenge facing these countries is how to bring debt down to safer levels in the face of a weak recovery. Several EU governments undertook large fiscal consolidations plans that involved a combination of spending cuts and tax hikes, aiming at sustainably reducing public deficits and debt. ", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["747191"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Adopting open innovation 2.0 by integrating responsible innovation for sustainability"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["OpenInnovationImpact"], "Technology_Description": "Due to both academic and family commitments over the coming year 1st October 2017 is the chosen indicative start date for this project", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["749423"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Ultrathin Mixed Matrix Membranes (MMMs) Derived from Metal-Organic Framework (MOF) Nanosheets for Organic Solvent Nanofiltration (OSN)"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["MONSON"], "Technology_Description": "Energy efficiency is at the heart of the EU\u2019s 2020 Strategy for smart, sustainable and inclusive growth. Organic solvent nanofiltration (OSN) technology is an emerging technology that can potentially achieve organic liquid separation on a molecular scale with less than half the energy consumption than conventional distillation processes. The main obstacle is the lack of OSN membrane materials with three key properties: high flux; high selectivity; and excellent stability. This project seeks to develop ultrathin OSN membranes comprising metal-organic framework (MOF) nanosheets in ultrathin polymer matrix in the form of mixed matrix membranes (MMMs). This research work is based on combining recent technology breakthroughs in: (i) 1-nm-thick MOF nanosheet based molecular sieve membranes, developed by the Applicant; and (ii) highly cross-linked sub-10-nm-thick OSN polymer membranes developed by the Host group. This is a timely and highly original research concept to create a new generation of high performances, and brings the full potential of MOF materials to the field of OSN membranes to produce highly stable OSN membranes with ultrafast solvent permeation and finely tunable (molecular weight cut-off) MWCO curves. In addition, the in-depth studies on controllable synthesis of MOF structures, rational design and synthesis of polymer networks, and microstructural optimization of MOF-polymer composites are expected to lead to application-oriented fabrication of high-performance membranes and functional thin films for a wide range of applications. This project will bring together the complementary expertise of both the applicant and the Host with the aim of developing mutually-beneficial research cooperation between Europe and China. This high-quality and highly innovative research will open up the optimum career possibilities for the applicant by broadening his research horizons, enriching his research experience, and strengthening his network with European colleagues.", "To": ["2019-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["705842"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["DOUGLAS CONNECT GMBH"], "EU_Contribution": ["EUR 187 419,60"], "Project_Title": ["ADVerse outcome Network for non-mutagenic CarcinogEns"], "Total_Cost": ["EUR 187 419,60"], "Country": ["Switzerland"], "Project_ACR": ["ADVaNCE"], "Technology_Description": "The field of toxicology is evolving from purely descriptive to a highly data\u2010rich science. To structure this large amount of data and in this way make the usage more effective for the safety assessors, the concept of adverse outcome pathways was established providing a means of understanding how chemicals induce adverse effects through their toxicity pathways and modes of action. However, there are some doubts if the one initiating event - one adverse outcome relationship enforced on AOPs by the OECD guideline is able to cover more complex adverse effects like hepatocellular carcinoma resulting from non-mutagenic chemical exposure. Therefore, the ADVaNCE project will demonstrate based on the just mentioned example that combining all existing knowledge into an adverse outcome network formed by interlinked AOPs is needed to cover all the pathways and intervention points activated in order to contribute to the development of hepatocellular carcinomas. Computational approaches will be used to extract important key events and their relationships from existing data sources and the relevant literature. These will be compared with existing AOPs and further experimental validation will be started. The computational and experimental result will finally guide the development of an integrated testing strategy completely based on in silico and in vitro data, which development and validation regarding regulatory usage will be continued after the project.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-SE - Society and Enterprise panel"], "Coordinated_in": ["Switzerland"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-10-01"], "Project_ID": ["750195"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CARDIFF UNIVERSITY", "UNIVERSITAT POLITECNICA DE CATALUNYA", "CONTROL INTEL-LIGENT DE L'ENERGIA SCCL", "UNIVERSIDADE DO PORTO", "EFACEC ENERGIA - MAQUINAS E EQUIPAMENTOS ELECTRICOS SA", "DANMARKS TEKNISKE UNIVERSITET", "KATHOLIEKE UNIVERSITEIT LEUVEN", "CG HOLDINGS BELGIUM NV", "ELIA SYSTEM OPERATOR"], "EU_Contribution": ["EUR 3 893 199,84"], "Project_Title": ["Innovative tools for offshore wind and DC grids"], "Total_Cost": ["EUR 3 893 199,84"], "Country": ["United Kingdom", "Spain", "Spain", "Portugal", "Portugal", "Denmark", "Belgium", "Belgium", "Belgium"], "Project_ACR": ["InnoDC"], "Technology_Description": "Europe\u2019s power system has seen significant changes in recent decades, notably the development of renewable energy ources. However, this transition is far from complete, and further changes are essential to make our energy system ready to play its part in realising the climate goals set at COP21. At present, renewable energy sources are increasing their share of electricity generation. This is particularly the case for offshore wind energy. InnoDC's 14 participants prepare 15 early career researchers to play their role in the energy transition that will take place over the next 20-40 years.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-09-01"], "Project_ID": ["765585"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["UNIVERSITAET LEIPZIG", "UNIVERSITAET LEIPZIG"], "EU_Contribution": ["EUR 1 341 250"], "Project_Title": ["Higher Co-dimension Singularities: Minimal Surfaces and the Thin Obstacle Problem"], "Total_Cost": ["EUR 1 341 250"], "Country": ["Germany", "Germany"], "Project_ACR": ["HiCoS"], "Technology_Description": "Singular solutions to variational problems and to partial differential equations are naturally ubiquitous in many contexts, and among these minimal surfaces theory and free boundary problems are two prominent examples both for their analytical content and their physical interest.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["759229"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITAET BASEL", "UNIVERSITAET BASEL"], "EU_Contribution": ["EUR 1 158 403"], "Project_Title": ["Engineering Topological Phases and Excitations in Nanostructures with Interactions"], "Total_Cost": ["EUR 1 158 403"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["ETOPEX"], "Technology_Description": "The main goal of this theory project is to propose engineered topological phases emerging only in strongly interacting systems and to identify the most feasible systems for experimental implementation. First, we will focus on setups hosting topological states localized at domain walls in one-dimensional channels such as parafermions, which are a new class of non-Abelian anyons and most promising candidates for topological quantum computing schemes. Second, in the framework of weakly coupled wires and planes, we will develop schemes for novel fractional topological phases in two- and three-dimensional interacting systems. To achieve these two goals, my team will identify necessary ingredients such as strong electron-electron interactions, helical magnetic order, or crossed Andreev proximity-induced superconductivity and address each of them separately. Later, we combine them to lead us to the desired topological phases and states. On our way to the main goal, as test cases, we will also study non-interacting analogies of the proposed effects such as Majorana fermions and integer topological insulators and pay close attention to the rapid experimental progress to come up with the most feasible proposals. We will study transport properties, scanning tunneling and atomic force microscopy. Especially for systems driven out of equilibrium, we will develop a Floquet-Luttinger liquid technique. We will explore the stability of engineered topological phases, error rates of topological qubits based on them, and computation schemes allowing for a set of universal qubit gates. We will strive to find a reasonable balance between topological stability and experimental feasibility of setups. Our main theoretical tools are Luttinger liquid techniques (bosonization and renormalization group), Green functions, Floquet formalism, and numerical simulations in non-interacting test models.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["757725"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 499 903"], "Project_Title": ["Optoelectronic of narrow band gap nanocrystals"], "Total_Cost": ["EUR 1 499 903"], "Country": ["France", "France"], "Project_ACR": ["blackQD"], "Technology_Description": "Over the past decades, silicon became the most used material for electronic, however its indirect band gap limits its use for optics and optoelectronics. As a result alternatives semiconductor such as III-V and II-VI materials are used to address a broad range of complementary application such as LED, laser diode and photodiode. However in the infrared (IR), the material challenge becomes far more complex.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-02-01"], "Project_ID": ["756225"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITY OF DURHAM", "UNIVERSITY OF DURHAM"], "EU_Contribution": ["EUR 1 499 557"], "Project_Title": ["A new vantage point on how gas flows regulate the build-up of galaxies in the early universe"], "Total_Cost": ["EUR 1 499 557"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["FEEDGALAXIES"], "Technology_Description": "Galaxies reside within a web of gas that feeds the formation of new stars. Following star formation, galaxies eject some of their gas reservoir back into this cosmic web. This proposal addresses the fundamental questions of how these inflows and outflows regulate the evolution of galaxies. My research team will tackle two key problems: 1) how gas accretion regulates the build-up of galaxies; 2) how efficiently outflows are in removing gas from star-forming regions. To characterise these flows across five billion years of cosmic history, we will pursue cutting-edge research on the halo gas, which is the material around the central galaxies, within dark matter halos. We will focus on scales ranging from a few kiloparsecs, where outflows originate, up to hundreds of kiloparsecs from galaxies, where inflows and outflows have visible impacts on halos. We will attack this problem using both simulations and observations with the largest telescopes on the ground and in space. With novel applications of absorption spectroscopy, we will gain a new vantage point on the astrophysics of these gas flows. Exploiting unprecedented datasets that I am currently assembling thanks to ground-breaking developments in instrumentation, we will directly connect the properties of halo gas to those of the central galaxies, investigating the impact that the baryonic processes probed in absorption have on galaxies seen in emission. In parallel, using new hydrodynamic simulations and radiative transfer calculations, we will go beyond present state-of-the-art methodologies to unveil the theory behind the origin of these gas flows, a crucial aspect to decode the physics probed by our observations. As a result of this powerful synergy between observations and simulations, this programme will provide the most advanced analysis of the impact that inflows and outflows have on galaxy evolution, shaping the direction of future work at 40m telescopes and the next generation of cosmological simulations.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["757535"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION", "FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Biophysical mechanisms of long-range transcriptional regulation"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["BioMeTRe"], "Technology_Description": "In mammals, transcriptional control of many genes relies on cis-regulatory elements such as enhancers, which are often located tens to hundreds of kilobases away from their cognate promoters. Functional interactions between distal regulatory elements and target promoters require mutual physical proximity, which is linked to the three-dimensional structure of the chromatin fiber. Chromosome conformation capture studies revealed that chromosomes are partitioned into Topologically Associating Domains (TADs), sub-megabase domains of preferential physical interactions of the chromatin fiber. Genetic evidence showed that TAD boundaries restrict the genomic range of enhancer-promoter communication, and that interactions between regulatory sequences within TADs are further fine-tuned by smaller-scale structures. However, the mechanistic details of how physical interactions translate into transcriptional outputs are totally unknown. Here we propose to explore the biophysical mechanisms that link chromosome conformation and long-range transcriptional regulation using molecular biology, genetic engineering, single-cell experiments and physical modeling. We will measure chromosomal interactions in single cells and in time using a novel method that relies on an enzymatic process in vivo. Genetic engineering will be used to establish a cell system that allows quantitative measurement of how enhancer-promoter interactions relate to transcription at the population and single-cell levels, and to test the effects of perturbations without confounding effects. Finally, we will develop physical models of promoter operation in the presence of distal enhancers, which will be used to interpret the experimental data and formulate new testable predictions. With this integrated approach we aim at providing an entirely new layer of description of the general principles underlying transcriptional control, which could establish new paradigms for research in epigenetics and gene regulation.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["759366"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN", "OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN"], "EU_Contribution": ["EUR 1 499 475"], "Project_Title": ["SPD nanostructured magnets with tuneable properties"], "Total_Cost": ["EUR 1 499 475"], "Country": ["Austria", "Austria"], "Project_ACR": ["SpdTuM"], "Technology_Description": "The decrease of weight and the increase of efficiency of magnetic components are essential for the reduction of CO2-emission and an improvement of their performance. Nanostructuring can dramatically improve the magnetic properties of soft and hard magnetic materials, hence opening up entirely new possibilities for the development of novel magnets. Nanocomposite magnets, for example, have been the focus of research since two decades. One of the remaining key challenges is to synthesize bulk nanostructured magnets of a reasonable size. In this project, this challenge is explicitly addressed and the potential to fabricate bulk nanostructured magnets by severe plastic deformation (SPD) as an innovative processing route is evaluated. The aim of the project is not only to synthesize different nanostructured magnets by SPD, but also to tailor their microstructure to attain the desired magnetic properties. It has been shown by the applicant that the magnetic properties of SPD processed nanocrystalline materials can be modified in wide range by decomposition of metastable solid solutions. By using different immiscible systems, decomposition mechanisms and annealing treatments, unique nanostructures can be obtained and the magnetic properties can be optimized. Through the choice of different magnetic starting materials, such as soft, hard and antiferromagnetic-ferromagnetic powders, different types of hard magnetic nanocomposites will also be obtained. Fine tuning of the microstructure and resulting magnetic properties through adjustments in the composition, SPD processing parameters and annealing treatments is planned. The project systematically addresses the entire process from the synthesis to the in-depth microstructural characterization by electron microscopy and atom probe tomography. In combination with simultaneous measurements of magnetic properties, the newly developed knowledge will be used to improve the performance of SPD processed nanostructured magnets.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Austria"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["757333"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY", "TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY", "BEN-GURION UNIVERSITY OF THE NEGEV", "INTERDISCIPLINARY CENTER (IDC) HERZLIYA"], "EU_Contribution": ["EUR 1 903 833"], "Project_Title": ["New Techniques for Secure Computation"], "Total_Cost": ["EUR 1 903 833"], "Country": ["Israel", "Israel", "Israel", "Israel"], "Project_ACR": ["NTSC"], "Technology_Description": "Secure computation is a general-purpose tool for processing sensitive data without compromising its", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["742754"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITAET BASEL", "UNIVERSITAET BASEL"], "EU_Contribution": ["EUR 1 488 387,50"], "Project_Title": ["Phononic Circuits: manipulation and coherent control of phonons"], "Total_Cost": ["EUR 1 488 387,50"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["PHONUIT"], "Technology_Description": "In the last decades, the power to control photons and electrons paved the way for extraordinary technological developments in electronic and optoelectronic applications. The same degree of control is still lacking with quantized lattice vibrations, i.e. phonons. Phonons are the carriers of heat and sound. The understanding and ability to manipulate phonons as quantum particles in solids enable the control of coherent phonon transport, which is of fundamental interest and could also be exploited in applications. Logic operations can be realized with the manipulation of phonons both in their coherent and incoherent form in order to switch, amplify, and route signals, and to store information. If brought to a mature level, phononic devices can become complementary to the conventional electronics, opening new opportunities.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["756365"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["LUNDS UNIVERSITET", "LUNDS UNIVERSITET"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["How our adaptive immune system separates \u201cself\u201d from \u201cforeign\u201d \u2013 a physicochemical study of binding in cell contacts"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["SELFOR"], "Technology_Description": "How can our immune system efficiently fight foreign pathogens at the same time as it is selective enough to leave our own cells alone? This, so called antigen discrimination, is still not understood on a molecular level. I will here illuminate this question by developing a physicochemical understanding of how T-cell receptors (TCRs) bind peptide-loaded major histocompatibility complexes (pMHCs), and importantly, how this differs for pMHC displaying self and foreign peptides. The interaction between TCRs and pMHCs on contacting immune cells is the first step in initiating an adaptive immune response. However, binding between membrane-anchored TCR and pMHC is a challenging physicochemical problem that has not been solved, and the binding kinetics is strongly affected by the membrane. Well-controlled measurements between TCR and pMHC under relevant conditions are needed to better understand the TCR/pMHC kinetics. A key discovery to achieve this is a method recently developed by me, which allows for extremely weak protein-protein interactions in contacting cells to be measured. I will in this project, backed up by immunologist in Oxford and theoretical chemists in Lund, build on this breakthrough and for the first time measure the binding kinetics between TCR in model cell membranes and pMHC on single cells, and how binding varies between self and foreign pMHC. Parameters such as adhesion molecules, applied force on the bond, the co-receptor CD4 and TCR clustering are all crucial for proper T-cell signalling, but their influence on the TCR/pMHC binding kinetics is unknown, and will here be studied. The obtained data will finally be used to evaluate, and improve on, kinetic models of antigen discrimination. Complemented with molecular dynamics simulations this altogether opens up for a fundamental understanding of binding between membrane-anchored molecules in general, and how this affects the TCR/pMHC interaction and antigen discrimination in particular.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["757797"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["Lindum AS"], "EU_Contribution": ["EUR 196 400,40"], "Project_Title": ["Developing commercial mushroom and vegetable production in an integrated food to waste to food biosystem."], "Total_Cost": ["EUR 196 400,40"], "Country": ["Norway"], "Project_ACR": ["VegWaMus CirCrop"], "Technology_Description": "VegWaMus CirCrop aim to develop commercial mushroom and vegetable production in an integrated food to waste to food biosystem. The project objective is on closing loop between biogas production based on food wastes and reuse of output after anaerobic digestion (AD). Mushroom and plant crop cultivation is usually performed through energy- and resource-intensive process (based on fossil or mineral resources), which generate wastes and the high CO2 footprint. Main emphasis has been on plant crops, but integrated mushroom cultivation has been found to be highly interesting from botCircular approach in which organic wastes are utilized for both energy (renewable biogas) and crop production in a closed system. Foodwaste treated in anaerobic digestion (AD) can be considered as a multicomponent organic fertiliser and byproduct for plant and mushroom cultivation substrate. Sustainable horticulture should reuse organic waste. The objectives of project will be achieved by indicating mushroom species which will be grown commercially on substrate based on digestate and vegetable plant grown rousing spent mushroom substrate (after cultivation). Combined cultivation will be incorporated in sustainable greenhouse environment in food to waste to food biosystem based on crop and substrate circulation. Lindum and associated partners have for several years developed more circular approach in which organic wastes are utilized for both energy(renewable biogas) and crops production in a closed system. Launched in 2016, Gr\u00f8nt Skifte AS, will realize a large R&D greenhouse unit located next to a new large anaerobic digestion (AD) plant. The unit will investigate and demonstrate full utilization of output CO2, heat and organic residue (digestate) from the AD. The large international interest towards the activities of Gr\u00f8nt Skifte is related to project\u2019s potential for helping governments and communities meeting the Paris Agreement. This is the circular and future way of food production.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-SE - Society and Enterprise panel"], "Coordinated_in": ["Norway"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-10-01"], "Project_ID": ["751052"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["STICHTING KATHOLIEKE UNIVERSITEIT BRABANT", "STICHTING KATHOLIEKE UNIVERSITEIT BRABANT"], "EU_Contribution": ["EUR 1 999 676"], "Project_Title": ["The Resilience and Evolution of Economic Activism and the Role of Law"], "Total_Cost": ["EUR 1 999 676"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["REVEAL"], "Technology_Description": "The global financial crisis put basic tenets of neoliberalism into question. Previous crises on product safety also exemplified the limits of delegating regulatory power. However, in the medium run, private regulatory bodies re-assume their previous powerful status and continue to exert undue influence on the functioning of economic activity.", "To": ["2022-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["725798"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["AARHUS UNIVERSITET", "AARHUS UNIVERSITET"], "EU_Contribution": ["EUR 1 499 406"], "Project_Title": ["Measurement-based dynamic control of mesoscopic many-body systems"], "Total_Cost": ["EUR 1 499 406"], "Country": ["Denmark", "Denmark"], "Project_ACR": ["MECTRL"], "Technology_Description": "Quantum control is an ambitious framework for steering dynamics from initial states to arbitrary desired final states. It has over the past decade been used extensively with immense success for control of low- dimensional systems in as varied fields as molecular dynamics and quantum computation. Only recently have efforts been initiated to extend this to higher-dimensional many-body systems. Most generic quantum control schemes to date, however, put quite heavy requirements on the controllability of either the system Hamiltonian or a set of measurement operators. This will in many realistic scenarios prohibit an efficient realization.", "To": ["2020-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-05-01"], "Project_ID": ["639560"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["UNIVERSIDAD DE ZARAGOZA", "UNIVERSIDAD DE ZARAGOZA"], "EU_Contribution": ["EUR 1 498 636"], "Project_Title": ["Is your heart aging well? A systems biology approach to characterize cardiac aging from the cell to the body surface"], "Total_Cost": ["EUR 1 498 636"], "Country": ["Spain", "Spain"], "Project_ACR": ["MODELAGE"], "Technology_Description": "Europe is facing a striking change in its demographics with an increasingly larger proportion of citizens aged 65 years and over. Aging is characterized by a progressive decline in the physiological functions of the body, with very notable effects on the heart. These effects are associated with a higher prevalence of arrhythmias, which, on top of deteriorating quality of life, increase the risk of other cardiovascular diseases like stroke, heart failure and neurological sequelae. Investigations targeting cardiac aging have often focused on assessing the effects of a specific contributing factor, at a single evaluation scale (molecular, cell, tissue, organ) and in many cases using animal species not relevant to humans in terms of aging mechanisms. MODELAGE proposes a multi-scale, multi-factorial research that is expected to make an important step in the characterization of human heart aging at both the population and individual levels. MODELAGE will work on an integrative methodological framework in which in silico modeling will be combined with in vitro cell and tissue analysis and in vivo electrocardiographic evaluation to investigate how cardiac aging manifests at a range of scales, from cell to body surface, and how electrical, structural and autonomic alterations contribute to such manifestations in humans. Indices describing spatio-temporal dynamics of cardiac electrophysiology will be evaluated in a population of young to senescent individuals using a novel feedback control approach. Inter-individual age-related variations in those indices will be assessed and correlated with markers of biological age (as opposed to chronological age). By investigating the mechanisms underlying inter-individual differences in cardiac dynamics, MODELAGE will set links to arrhythmia susceptibility and will propose novel non-invasive markers to identify high-risk senescent individuals for which preventive anti-arrhythmic treatment should be considered.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["638284"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["ISTANBUL TEKNIK UNIVERSITESI", "ECOLE NATIONALE SUPERIEURE ARTS INDUSTRIES TEXTILES", "ANOTATO EKPAIDEYTIKO IDRIMA PEIRAIA TECHNOLOGIKOY TOMEA", "KIVANC KIMYA SANAYII VE TICARET ANONIM SIRKETI", "INLAS INTELEKTUALNA LASTNINA IN SVETOVANJE DOO", "TEXNOLOGIES FOTONIKON KAI HLEKTRONIKON SYSTHMATVN AE", "THE UNIVERSITY OF MANCHESTER", "UNITED MEDICAL INNOVATION LTD"], "EU_Contribution": ["EUR 913 500"], "Project_Title": ["Welding of E-Textiles for Interactive Clothing"], "Total_Cost": ["EUR 1 206 000"], "Country": ["Turkey", "France", "Greece", "Turkey", "Slovenia", "Greece", "United Kingdom", "United Kingdom"], "Project_ACR": ["ETexWeld"], "Technology_Description": "The new field of science dealing with implementation of electronics to textiles in combination with informatics is known as e-textiles. This project proposal leads to knowledge transfer among partners in order to develop innovative e-textile products for interactive protective clothing and footwear using welding technologies by bringing experts from different countries, sectors and disciplines together to focus their effort in innovative e-textile product designs. ", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Turkey"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["644268"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["UNIVERSITAT ZURICH", "SCUOLA IMT (ISTITUZIONI, MERCATI, TECNOLOGIE) ALTI STUDI DI LUCCA", "GCF - GLOBAL CLIMATE FORUM EV", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "INSTITUT JOZEF STEFAN", "LONDON CENTRE FOR MATHEMATICAL SCIENCES LBG", "SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO SANT'ANNA", "FONDATION NATIONALE DES SCIENCES POLITIQUES", "INSTITUTE FOR ADVANCED SUSTAINABILITY STUDIES EV", "THE UNIVERSITY OF SUSSEX", "UNIVERSIDAD DE ZARAGOZA", "THE YOUNG FOUNDATION LBG", "SIGMA ORIONIS SA", "FINANCE WATCH AISBL", "PLUSVALUE", "UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 3 270 646,74"], "Project_Title": ["Distributed Global Financial Systems for Society"], "Total_Cost": ["EUR 4 250 000"], "Country": ["Switzerland", "Italy", "Germany", "France", "Slovenia", "United Kingdom", "Italy", "France", "Germany", "United Kingdom", "Spain", "United Kingdom", "France", "Belgium", "United Kingdom", "United Kingdom"], "Project_ACR": ["DOLFINS"], "Technology_Description": "The DOLFINS project addresses the global challenge of making the financial system better serve society by placing scientific evidence and citizens participation at the centre of the policy process in finance. The project strives to give scientific evidence and citizens participation central roles in the policy process concerning finance. DOLFINS will focus on two crucial and interconnected policy areas that will shape the public debate in the coming 5 years: How to achieve financial stability and how to facilitate the long-term investments required by the transition to a more sustainable, more innovative, less unequal and greener EU economy. The expected impact is to achieve crucial advances in reshaping the policy process to overcome the financial and political crisis faced by the EU. We will deliver quantitative tools to evaluate policies aiming to tame systemic risk and to foster sustainable investing. The tools will be based on fundamental research combining network models and algorithmic game theory with broader economic insights. This approach can provide a more satisfactory understanding of credit, risk and sustainable investments in an interconnected world. We will investigate how to engage citizens in the early stage of the policy making process and will develop evidence-based narratives in order to better shape policies in the public interest. To this end, our project will take advantage of semantic web technologies, big data and ICT in general. Given the highly technical nature of key issues in finance, we will explore how ICT and art can facilitate citizens\u2019 engagement through innovative narratives, leading to better coordinated actions of stakeholders.", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["FETPROACT-1-2014 - Global Systems Science (GSS)"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2015-03-01"], "Project_ID": ["640772"], "Call_for_Proposal": ["H2020-FETPROACT-2014"]}, -{"Partners": ["AARHUS UNIVERSITET", "KOBENHAVNS UNIVERSITET", "THE UNIVERSITY OF WARWICK", "UNIVERSIDAD NACIONAL DE LA PLATA", "UNIVERSITE DE BORDEAUX", "DANMARKS TEKNISKE UNIVERSITET", "MINISTERIUM FUER UMWELT, LANDWIRTSCHAFT, ERNAEHRUNG, WEINBAU UND FORSTEN RHEINLAND- PFALZ", "UNIVERSIDAD DE ZARAGOZA", "INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE", "UNIVERSIDADE CATOLICA PORTUGUESA", "Instituto Superior de Agronomia", "STICHTING VU", "INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE"], "EU_Contribution": ["EUR 3 945 597,12"], "Project_Title": ["MICROWINE - Microbial metagenomics and the modern wine industry"], "Total_Cost": ["EUR 3 945 597,12"], "Country": ["Denmark", "Denmark", "United Kingdom", "Argentina", "France", "Denmark", "Germany", "Spain", "France", "Portugal", "Portugal", "Netherlands", "France"], "Project_ACR": ["MICROWINE"], "Technology_Description": "A diverse, complex, and poorly characterised community of microorganisms lies at the heart of the wine \u2013 an industry worth over \u20ac220 billion globally. These microorganisms play key roles at all stages of the viniculture and vinification processes, from helping plants access nutrients from the soil, driving their health through protection against pathogens, to fermentation processes that transform the must into wine with its complex array of aromas and flavours. Given this importance, an improved understanding of the microbial community and its interplay will have significant effects on the industry. In recent years, 'Next Generation' DNA sequencing has revolutionised many areas of biology, including microbiology, through conferring the ability to characterise microbes on the deep community scale, through both \u2019shotgun\u2019 and \u2019deep amplicon\u2019 sequencing approaches. To exploit this power for the benefit of the wine industry, we propose MICROWINE, a 15 ESR Marie Curie Actions European Training Network. The network is constructed as a close collaboration between industry and academic partners, around the theme of the microbial community\u2019s role in the wine production process. Through combining microbial metagenomic sequencing with powerful computation analyses, with metadata generated using techniques such as metabolomics and geochemistry, we will study the action of microbes from the plant protection and nutrition, through to wine fermentation process, using samples collected from both Europe and beyond. We will further train the ESRs across a wide range of relevant disciplines, and maximise information transfer through multiple host and academic-industry cosupervision and secondments. In this way, we anticipate contributing to the strength and scientific progress of the wine industry through training of a cohort of leading, interdisciplinary and tightly interconnected scientists at the forefront of modern microbiological, genomic, computational and related techniques.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2015-01-01"], "Project_ID": ["643063"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["UNIVERSITATEA ALEXANDRU IOAN CUZA DIN IASI", "UNIVERSITATEA DIN CRAIOVA", "UNIVERSITATEA DE VEST DIN TIMISOARA", "UNIVERSITATEA DIN BUCURESTI", "UNIVERSITATEA BABES BOLYAI", "UNIVERSITATEA LUCIAN BLAGA DIN SIBIU", "INSTITUTUL DE FIZICA ATOMICA", "INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU FIZICA LASERILOR PLASMEI SI RADIATIEI", "\"INSTITUTUL NATIONAL DE CERCETARE -DEZVOLTARE PENTRU FIZICA SI INGINERIE NUCLEARA \"\"HORIA HULUBEI\"\" (IFIN-HH)\"", "INSTITUTUL DE STIINTE SPATIALE"], "EU_Contribution": ["EUR 118 316"], "Project_Title": ["RESEARCHERS' NIGHT in ROMANIA. Do you speak science?"], "Total_Cost": ["EUR 118 316,25"], "Country": ["Romania", "Romania", "Romania", "Romania", "Romania", "Romania", "Romania", "Romania", "Romania", "Romania"], "Project_ACR": ["RoTalkScience"], "Technology_Description": "The general objective of the project is to promote scientific research in Romania and to share to general public the enthusiasm of professionals working in this field. ", "To": ["2015-12-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-NIGHT-2014 - European Researchers' Night (NIGHT)"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Romania"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations"], "From": ["2014-05-01"], "Project_ID": ["633311"], "Call_for_Proposal": ["H2020-MSCA-NIGHT-2014"]}, -{"Partners": ["SLOVENSKA ORGANIZACIA PRE VYSKUMNEA VYVOJOVE AKTIVITY ZDRUZENIE", "SLOVENSKA AKADEMIA VIED", "I-EUROPA SRO", "CENTRUM VEDECKO TECHNICKYCH INFORMACII SLOVENSKEJ REPUBLIKY"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Festival of Science European Researchers' Night 2014 - 2015 in Slovakia"], "Total_Cost": ["EUR 150 000"], "Country": ["Slovakia", "Slovakia", "Slovakia", "Slovakia"], "Project_ACR": ["ERN14-15SVK"], "Technology_Description": "\"Sovva, n.o. has been organising the festival of science Researchers\u00b4night in Slovakia since 2007. The recent festival featured more than 1000 researchers and attended by nearly 177000 visitors. To continue in this succesful effort we have prepared the new concept for ERN 2014-15 with the following lead ideas: Science is Adventure and Experience the Science. The target is to challenge people to face the Science and to discover its beauty with aim to attracting the young generation to study science. The festival will present the most interesting research findings in Slovakia by leading Slovak universities, research institutes of the Slovak Academy of Sciences as well as representatives of innovative companies supporting R&D activities. The science shows will be held in shopping malls, but there will be also a number of side events in museums and observatories as well as discussions, lectures and various competitions. A wide range of activities will cover all country\u00b4s territory (Bratislava, Banska Bystrica, Zilina, Kosice, Tatranska Lomnica). All festival venues in the five cities will offer opportunities to spend the day and night visiting the interesting presentations and lectures, test scientific applications, get in touch with the latest research outcomes and to speak with researchers. Thanks to the direct discussions with them people can discover their \"\"human face\"\". Since efforts during the event and also during awareness campaign will focus mostly on examples showing how interesting and important the career of researcher is, we believe the ERN 2014-15 will help us to tackle the still existing stereotypes about researchers and science and encouraging young people to embark on scientific careers. To support the ERN impact, event venues will be linked through live streaming and as a member of Eusea we will use also this platform to provide the virtual and real connections between cities, venues and countries for exchange and collaboration.\"", "To": ["2015-11-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-NIGHT-2014 - European Researchers' Night (NIGHT)"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Slovakia"], "Activity": ["Other", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2014-05-01"], "Project_ID": ["633288"], "Call_for_Proposal": ["H2020-MSCA-NIGHT-2014"]}, -{"Partners": ["DRUSTVO ZNANOST.ORG", "SVEUCILISTE U SPLITU", "SVEUCILISTE U ZAGREBU FAKULTET ELEKTROTEHNIKE I RACUNARSTVA"], "EU_Contribution": ["EUR 107 430"], "Project_Title": ["CRO-EU-REKA! Research For Innovation, Innovation For People"], "Total_Cost": ["EUR 144 750"], "Country": ["Croatia", "Croatia", "Croatia"], "Project_ACR": ["CRO-EU-REKA"], "Technology_Description": "\"The project \u201cCRO-EU-REKA!\u201d will carry out preparations, promotion, organization and impact assessment of the European Researchers' Night events to be organized in Zagreb and Split, the two largest cities in the Republic of Croatia, on 26th September 2014 and 25th September 2015. ", "To": ["2015-11-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-NIGHT-2014 - European Researchers' Night (NIGHT)"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Croatia"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2014-05-01"], "Project_ID": ["633305"], "Call_for_Proposal": ["H2020-MSCA-NIGHT-2014"]}, -{"Partners": ["ESCIENCIA EVENTOS CIENTIFICOS SL", "UNIVERSIDAD DE ZARAGOZA", "FUNDACION AGENCIA ARAGONESA PARA LA INVESTIGACION Y EL DESARROLLO"], "EU_Contribution": ["EUR 110 000"], "Project_Title": ["European Reseearchers Night: Researchers in Real Life."], "Total_Cost": ["EUR 287 850"], "Country": ["Spain", "Spain", "Spain"], "Project_ACR": ["ESC"], "Technology_Description": "\u201cResearchers in Real Life\u201d is the project to show people of Aragon, researchers are common people and their work is in our daily life, in a festive mood with activities in City Center streets. After three years European Researchers Night has become an important event in Saragossa. ", "To": ["2015-11-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-NIGHT-2014 - European Researchers' Night (NIGHT)"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Spain"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Other"], "From": ["2014-05-01"], "Project_ID": ["633260"], "Call_for_Proposal": ["H2020-MSCA-NIGHT-2014"]}, -{"Partners": ["AARHUS UNIVERSITET", "LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN", "TECHNISCHE UNIVERSITAET MUENCHEN", "KAROLINSKA INSTITUTET", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA", "ATDBIO LIMITED"], "EU_Contribution": ["EUR 3 979 632,96"], "Project_Title": ["DNA-Based Modular Nanorobotics"], "Total_Cost": ["EUR 3 979 632,96"], "Country": ["Denmark", "Germany", "Germany", "Sweden", "United Kingdom", "Italy", "United Kingdom"], "Project_ACR": ["DNABOT"], "Technology_Description": "Robotic systems essentially comprise sensors and actuators connected to and coordinated by an information-processing unit. These principles apply to the human scale robotic systems that currently transform the way we work and live. With DNA-Based Modular Robotics (DNABOT) we will take the first steps to scale advanced robotic behavior to the molecular scale for future medical and technological applications. DNABOT brings together the leading research groups in DNA nanotechnology in Europe to collectively develop an integrated and modular robotic platform and demonstrate applications of the novel technology. DNA-based construction is a natural modular platform, which via the programmability of sequence design and self-assembly allows different structural and functional motifs to be flexibly combined. DNA modules will be developed with a range of novel functions for sensing, actuation and intra-system communication and computing, implementing all of the typical components required for a robotic system at the molecular level. Our overall goal is the creation of the first \u201cindustry standard\u201d for modular robotics by the establishment of a modular \u201cplug-and-play\u201d platform that allows the construction of custom-made nanorobots for advanced applications in research and industry. The ESRs will be trained in and develop functional modules that in close collaboration among the ESRs and Partners will be assembled to advanced molecular robots. The highly interdisciplinary research and training program will exploit the synergy between the different competences of the Partners. The innovative and applied focus is supported by the involvement of the company ATDBio as Beneficiary and five companies as Partner Organization that will also provide complementary skills training and intersectoral exposure of the ESRs. This proposal takes the first steps for future application of nanoscale robots in research and industry and will train future generations of researchers in this field.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-01-01"], "Project_ID": ["765703"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE", "ISTITUTO NAZIONALE DI FISICA NUCLEARE", "UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II.", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN", "PANGEA FORMAZIONE SRL", "LUNDS UNIVERSITET", "UNIVERSITETET I OSLO", "EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH", "THE UNIVERSITY OF EDINBURGH"], "EU_Contribution": ["EUR 3 026 260,26"], "Project_Title": ["International Training Network for Statistics in High Energy Physics and Society"], "Total_Cost": ["EUR 3 026 260,26"], "Country": ["United Kingdom", "Italy", "Italy", "Germany", "Netherlands", "Italy", "Sweden", "Norway", "Switzerland", "United Kingdom"], "Project_ACR": ["INSIGHTS"], "Technology_Description": "The INSIGHTS Innovative Training Network will develop advanced statistical methods, implement them in software, and apply them to solve problems in Particle Physics and other fields. In doing so, we will create the next generation of experts not only able to investigate Nature's fundamental particles but also to solve problems of broad relevance to society. The analysis of data collected in Particle Physics experiments such as those at the Large Hadron Collider (LHC) poses tremendous challenges, and advanced statistical methods have proven to be key elements of recent advances in the field. INSIGHTS will enable significant further progress with particular emphasis on multivariate analysis, parametric modelling and Bayesian computation. We will ensure that the statistical tools can cope with the complexities of real experimental settings by using them in actual analyses, such as searches for new fundamental particles at the LHC. In carrying out the proposed research, INSIGHTS will train a cohort of physicists in modern statistical methods and establish collaborations and educational structures that will continue long into the future. In particular we plan to establish a new Pan-European Advanced School of Statistics, which will take the training of EU researchers to a higher level. The participating institutes in INSIGHTS have a successful track record of and innovation and education in statistical data analysis, and their expertise will form the core of the training provided. In addition, secondments with partners in other disciplines such as Finance, Climate Science and Volcanology will allow participants to view statistical and computational problems from multiple viewpoints and to exchange ideas between these areas and Particle Physics.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["765710"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["ACADEMISCH ZIEKENHUIS GRONINGEN", "INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE", "HELSINGIN YLIOPISTO", "WEIZMANN INSTITUTE OF SCIENCE", "UNIVERSITETET I OSLO", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "EBERHARD KARLS UNIVERSITAET TUEBINGEN", "INSTITUTE OF CANCER RESEARCH - ROYAL CANCER HOSPITAL", "KING'S COLLEGE LONDON", "ANAXOMICS BIOTECH, S.L.", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.", "ADJUVATIS", "QPS NETHERLANDS BV", "UNIVERSITAETSKLINIKUM FREIBURG"], "EU_Contribution": ["EUR 3 890 064,96"], "Project_Title": ["Driving next generation autophagy researchers towards translation"], "Total_Cost": ["EUR 3 890 064,96"], "Country": ["Netherlands", "France", "Finland", "Israel", "Norway", "Spain", "Germany", "United Kingdom", "United Kingdom", "Spain", "Germany", "France", "Netherlands", "Germany"], "Project_ACR": ["DRIVE"], "Technology_Description": "The manipulation of autophagy has an enormous therapeutic potential to revolutionize the way we currently treat cancers, neurodegenerative disorders, inflammatory and infectious diseases. Despite the great promises made by pioneering medical studies, the still limited applied research on autophagy has hampered the translation of fundamental knowledge into clinical-grade products and improved healthcare. Applied autophagy research is essential to understand the roles of autophagy in the different physiological and pathological situations, to generate (disease) models and develop biomarkers and assays to assess its progress.", "To": ["2021-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["765912"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSITE DE STRASBOURG", "UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "LATVIJAS UNIVERSITATE", "THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN", "INSTITUT JOZEF STEFAN", "Kolektor Group d.o.o., vodenje in upravljanje dru\u017eb", "ELVESYS SAS"], "EU_Contribution": ["EUR 3 757 056,48"], "Project_Title": ["Magnetics and Microhydrodynamics - from guided transport to delivery"], "Total_Cost": ["EUR 3 757 056,48"], "Country": ["France", "France", "Spain", "Germany", "Latvia", "Ireland", "Slovenia", "Slovenia", "France"], "Project_ACR": ["MAMI"], "Technology_Description": "This multidisciplinary network entitled: \u201cMagnetics and Microhydrodynamics - from guided transport to delivery\u201d (MaMi) bridges the research fields of fluidics and magnetism, by taking advantage of magnetic forces to control local flows and cargo transport inspired by biomimetic systems. Using magnetic sources, as well as high magnetic susceptibility liquids or nanostructures, devices with unique anti-fouling properties and non-slip boundary conditions can be realized. Our scientific aim is to take advantage of such unique wall-less properties to create new applications of microfluidic technology for life sciences. The network assembles and interdisciplinary team of seven academic and five non-academic partners, exposes all students to industrial environments, and ensures training at the frontiers of two well-established research fields, which are not commonly associated. Over the course of their projects, early stage researchers based in academic institutions will experience working environments in at least 3 different countries. Training a new generation of researchers will bring new cutting-edge knowledge, and will ensure a high potential for industrial applications to promote EU leadership.", "To": ["2022-04-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-05-01"], "Project_ID": ["766007"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["UNIVERSITAET BIELEFELD", "UNIVERSITETET I TROMSOE", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "GOETEBORGS UNIVERSITET", "THE UNIVERSITY OF BIRMINGHAM", "VRIJE UNIVERSITEIT BRUSSEL", "LAVISION BIOTEC GMBH", "CHERRY BIOTECH", "ELVESYS SAS"], "EU_Contribution": ["EUR 3 728 513,16"], "Project_Title": ["Super-resolution optical microscopy of nanosized pore dynamics in endothelial cells"], "Total_Cost": ["EUR 3 728 513,16"], "Country": ["Germany", "Norway", "United Kingdom", "Sweden", "United Kingdom", "Belgium", "Germany", "France", "France"], "Project_ACR": ["DeLIVER"], "Technology_Description": "DeLIVER will train a new generation of ESRs in the development and application of newly developed high speed and high resolution imaging tools in biomedical research. ESRs will be cross-pollinated with concepts and skills in physics and biomedicine, in particular in super-resolution optical imaging (a.k.a. optical nanoscopy), analytical image reconstruction, and optical micro-manipulation methods. These skills are applied to reveal for the first time the function and dynamics of nanosized pores in endothelial cells (EC) that present the main barrier between the blood and vital organs for human physiology, such as the liver, brain, kidneys, and the eyes. Very little is known about the extremely important physiological function of these unique structures and their role in the transfer and/or clearance of metabolites and pharmaceuticals to vital organs. The current generation of optical nanoscopes, however, is rather slow and can only be applied to isolated, typically fixed (i.e. dead) cells rather than biomedically relevant tissues. Also, newcomers to the field need to familiarize themselves with a whole new set of potential problems that might arise in the use of optical nanoscopy, such as image reconstruction-related artifacts to name just one example.This is an area of research where European enterprises are very active. Excellent training in new scientific and complementary skills, combined with international and intersectoral work experience, will instil an innovative, creative and entrepreneurial mind-set in DeLIVER's ESRs, maximising economic benefits based on scientific discoveries. These specialised, highly trained, and mobile ESRs will have greatly enhanced career prospects. The training in novel physical methods with highly relevant experience in the biomedical sciences will allow them to confidently navigate at the interface of academic, clinical and private sector research.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-01-01"], "Project_ID": ["766181"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["KUNGLIGA TEKNISKA HOEGSKOLAN", "FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)", "UNIVERSIDAD DE VIGO", "KING'S COLLEGE LONDON", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "INSTITUTE OF CANCER RESEARCH - ROYAL CANCER HOSPITAL", "UNIWERSYTET WARSZAWSKI"], "EU_Contribution": ["EUR 3 863 978,28"], "Project_Title": ["Computational ONcology TRaining Alliance"], "Total_Cost": ["EUR 3 863 978,28"], "Country": ["Sweden", "Spain", "Spain", "United Kingdom", "United Kingdom", "Switzerland", "United Kingdom", "Poland"], "Project_ACR": ["CONTRA"], "Technology_Description": "Cancer is a major cause of death and suffering, rendering it a huge concern to the general public. Consequently, it has been targeted by application of the molecular techniques developed during the last 20-25 years, thereby improving diagnosis and treatment. Nevertheless, although current biomarker and treatment concepts often are successful initially, they subsequently frequently fail to achieve durable drug response and long-term survival for cancer patients. The study of somatic evolution in cancer is a very promising approach to rectify this situation. Fortunately, single cell genomic sequencing has recently begun to provide opportunity to unprecedented detailed insights into tumour evolution and new techniques are emerging for assaying the spatial distribution of tumour heterogeneity. Analysing and developing methods for these emerging data sets are under-researched areas that lie at the intersection of medical, evolutionary biology, and computational research. In CONTRA, European researchers with complementary expertise have joined forces in order to collectively facilitate training of future European computational cancer researchers. We will by applying modern recruitment and selection methods in combination with offering excellent training and employments conditions, including social security, facilitate recruitment of 15 excellent ESRs, across genders and geographical areas. We will train these 15 ESRs in the mathematical, computational, and applied skills required to tackle the complex analysis problems posed by somatic evolution in cancer. We will also teach them entrepreneurship and the requirements of pharmaceutical and biotech industry. Using a novel scheme, this substantial academic cancer expertise will be complemented with industrial expertise in software development, especially for biotech and pharmaceutical industry, which will unleash key components of the innovative force of the European commercial sector in the struggle against cancer.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["766030"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["STICHTING KATHOLIEKE UNIVERSITEIT", "SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI DI TRIESTE", "UNIVERSITY COLLEGE LONDON", "WEIZMANN INSTITUTE OF SCIENCE", "NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU", "INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE", "UNIVERSITE D'AIX MARSEILLE", "Janssen Pharmaceutica NV"], "EU_Contribution": ["EUR 3 961 159,56"], "Project_Title": ["Memory research: Ground-breaking, Applied, and Technological Exchanges"], "Total_Cost": ["EUR 3 961 159,56"], "Country": ["Netherlands", "Italy", "United Kingdom", "Israel", "Norway", "France", "France", "Belgium"], "Project_ACR": ["M-GATE"], "Technology_Description": "In M-GATE, ESRs will combine state-of-the art experimental neurophysiology, innovative technologies, and advanced theoretical approaches to unveil memory mechanisms, from single neurons to brain networks, to cognition and behaviour, addressing the healthy and diseased brain. Through research and training from top-class scientists and close interaction with industrial partners, ESRs will develop unique multi-disciplinary skills combining physiology, molecular biology, computation, micro-engineering, and entrepreneurship", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-10-01"], "Project_ID": ["765549"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["THE UNIVERSITY OF READING", "UNIVERSITAT KONSTANZ", "UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA", "UNIWERSYTET JAGIELLONSKI", "UNIVERSIDAD POMPEU FABRA", "UNIVERSITEIT LEIDEN", "ARISTOTELIO PANEPISTIMIO THESSALONIKIS", "UNIVERSITI PUTRA MALAYSIA", "UNIVERSITE DE GENEVE", "IRCCS - ASSOCIAZIONE LA NOSTRA FAMIGLIA 'ISTITUTO SCIENTIFICO EUGENIO MEDEA'", "CENTRO PROVINCIALE PER L'ISTRUZIONEDEGLI ADULTI PALERMO 1"], "EU_Contribution": ["EUR 3 778 888,68"], "Project_Title": ["The Multilingual Mind"], "Total_Cost": ["EUR 3 778 888,68"], "Country": ["United Kingdom", "Germany", "Italy", "Poland", "Spain", "Netherlands", "Greece", "Malaysia", "Switzerland", "Italy", "Italy"], "Project_ACR": ["MultiMind"], "Technology_Description": "The aim of the project \u2018MultiMind\u2019 is to establish an international, multidisciplinary and multisectorial training network on multilingualism. Given the current migration and refugee crisis in Europe, there is an urgent need to provide an in depth investigation of multilingualism from a multidisciplinary perspective that will bridge the gap between fundamental and applied research and will addresses societal challenges within the education and health sector as well as challenges related to the education of migrants and refugees in Europe. MultiMind addresses the benefits and challenges of multilingualism through an innovative research programme that combines fundamental and applied research across disciplines in a range of different social and educational settings. It investigates the influence of multilingualism on language learning, cognition, creativity, and decision making, on brain function and structure, and its role as a reserve in atypical populations using a combination of cutting edge research methodologies. MultiMind is composed of 9 academic and 2 non-academic organisations as well as 16 partners in leading academic institutions, companies, health organisations and 5 branches of Bilingualism Matters, a leading international network of centres that provide outreach activities on multilingualism. The consortium brings together researchers with complementary expertise within the disciplines of linguistics, psychology, education, neuroscience, and speech & language therapy along with non-academic partners within the education and health sectors, IT and publishing. This will enable to address societal challenges within education and health as well as challenges related to the migration and refugee crisis in Europe whilst training a new generation of researchers in world-leading labs using cutting edge methodologies and allowing them to build the necessary skills fostering their career progress as independent researchers in academic or nonacademic sectors.", "To": ["2022-03-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2018-04-01"], "Project_ID": ["765556"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["HUMBOLDT-UNIVERSITAET ZU BERLIN", "UNIVERSITAET BERN", "UNIVERSITAT AUTONOMA DE BARCELONA", "KOBENHAVNS UNIVERSITET", "UNIVERSITAET KLAGENFURT", "STICHTING VU", "LEUPHANA UNIVERSITAT LUNEBURG", "UNIVERSITE CATHOLIQUE DE LOUVAIN", "THE FOREST TRUST LBG", "UNILEVER U.K. CENTRAL RESOURCES LIMITED"], "EU_Contribution": ["EUR 3 895 103,16"], "Project_Title": ["Operationalising telecouplings for solving sustainability challenges related to land use"], "Total_Cost": ["EUR 3 895 103,16"], "Country": ["Germany", "Switzerland", "Spain", "Denmark", "Austria", "Netherlands", "Germany", "Belgium", "United Kingdom", "United Kingdom"], "Project_ACR": ["COUPLED"], "Technology_Description": "Society depends on land for food, feed, fibre and energy, but the detrimental outcomes of unsustainable land practices are becoming increasingly apparent. Ensuring sustainable land use is a key challenge, yet hard to achieve in today\u2019s interconnected world where policies, consumer demands and environmental change in one region may affect far-away places. We face a significant knowledge gap regarding the processes related to land use that link distant places \u2013 or telecouplings \u2013 and how these processes could be governed towards sustainability. Companies, institutions and policy makers lack the expertise and tools to ensure sustainable land use in a globalised world. COUPLED will educate researchers and entrepreneurs in assessing and governing land use in a systemic way, accounting for the opportunities and threats arising from distal links between Europe and other regions. COUPLED builds on a strong interdisciplinary network to achieve its overall objective of operationalising the novel telecouplings concept in order to support sustainable governance of land systems and related supply chains under global change. COUPLED will deliver on training a new generation of professionals and entrepreneurs, developing rich analytic tools and new understandings to help private and public organisations to identify where and how they can intervene to make sustainable land use decisions, thereby avoiding unwanted outcomes. The consortiums unites scientifically excellent partners across the natural and social sciences to ensure excellence in research, institutional and technological innovation. Working closely with large companies, SMEs, NGOs, international organisations and administrative bodies, the ESRs will learn how to move between science and practice, become highly attractive to employers, and build successful careers in research, consulting, industry or governance. The action will thus contribute to Europe\u2019s leading position for a transformation towards sustainable land use.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-01-01"], "Project_ID": ["765408"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["UNIVERSITY OF LEEDS", "UNIVERSITY OF HULL", "UNIVERSIDADE DO MINHO", "UNIVERSITETET I OSLO", "JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN", "HELSINGIN YLIOPISTO", "EBERHARD KARLS UNIVERSITAET TUEBINGEN", "LUNDS UNIVERSITET", "INSTITUT PASTEUR", "BIOMERIEUX SA", "CENTITVC - CENTRO DE NANOTECNOLOGIA E MATERIAIS TECNICOS FUNCIONAIS E INTELIGENTES ASSOCIACAO"], "EU_Contribution": ["EUR 3 925 220,40"], "Project_Title": ["VIral and BacteRial Adhesin Network Training"], "Total_Cost": ["EUR 3 925 220,40"], "Country": ["United Kingdom", "United Kingdom", "Portugal", "Norway", "Germany", "Finland", "Germany", "Sweden", "France", "France", "Portugal"], "Project_ACR": ["ViBrANT"], "Technology_Description": "ViBrANT (VIral and BacteRial Adhesin Network Training) brings together an interdisciplinary team of world-leading European infection researchers, focused on a cutting-edge translational research project to understand host-pathogen adhesion and to develop novel, highly-specific nanoscale diagnostics to improve patient care. Host-pathogen interactions are the basis for infectious diseases, but the research methodologies needed to unravel these interactions and translate them into viable diagnostic tools are complex and change rapidly. ", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["765042"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["LEUPHANA UNIVERSITAT LUNEBURG"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["What Epistemology for Sustainability Science? Experiments and Theories for Social Transformation"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["EPISUS"], "Technology_Description": "Sustainability science is an innovative research field dealing with complex socio-ecological problems of our time, from climate change and rapid urbanization to pandemics and loss of biodiversity. A major goal for sustainability science is to support societal transformations towards sustainability by generating, testing, and integrating (1) system knowledge about sustainability problems, (2) target knowledge about desirable futures, and (3) transformational knowledge about effective interventions that can lead from the problems detected to the desirable futures. Thus far, epistemological work has focused primarily on the foundations of system and target knowledge and has neglected transformational knowledge. Therefore, a major task for an epistemology of sustainability science is now to understand how transformational knowledge is generated and tested. Because of the central role they play in transformational sustainability science, in EPISUS, I take transformational experiments as entrance point to develop an epistemology of transformational sustainability science. I ask: What kind of sustainability science do we need to generate and test transformational knowledge and what role can transformational experiments play in this science? In EPISUS, I address this question by focusing on: 1. the main characteristics of transformational experiments, 2. the criteria used to evaluate experimental results and 3. the kind of theories that support, or could support, the production of transformational knowledge. I use a research design that combines the investigation of concrete examples of transformational experiments and conceptual reflections using analytical tools from the philosophy of science. EPISUS will provide a new conceptualization of transformational experiments as well as categories for the further development of transformational approaches in sustainability science that are theoretically sound and evidence-based.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["752135"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["STICHTING VUMC", "UNIVERSITAETSKLINIKUM HAMBURG-EPPENDORF", "INSTITUT DE INVESTIGACIO EN CIENCIES DE LA SALUT GERMANS TRIAS I PUJOL", "FUNDACAO D. ANNA SOMMER CHAMPALIMAUD E DR. CARLOS MONTEZ CHAMPALIMAUD", "CENTRE HOSPITALIER UNIVERSITAIRE MONTPELLIER", "PLOVDIVSKI UNIVERSITET PAISIY HILENDARSKI", "UNIVERSIDAD DE GRANADA", "PANGAEA BIOTECH SL", "EXOSOMICS SIENA SPA"], "EU_Contribution": ["EUR 3 727 722,96"], "Project_Title": ["European Liquid Biopsies Academy - Towards widespread clinical application of blood-based diagnostic tools"], "Total_Cost": ["EUR 3 727 722,96"], "Country": ["Netherlands", "Germany", "Spain", "Portugal", "France", "Bulgaria", "Spain", "Spain", "Italy"], "Project_ACR": ["ELBA"], "Technology_Description": "Liquid biopsies have been heralded as a game changer in cancer management, with blood tests offering a minimally invasive, safe, and sensitive alternative or complimentary approach for tissue biopsies. Blood represents a rich source of information through which solid cancers (and their subtypes) can be detected, identified and classified, and matched to a specific therapy. However, despite the potential of individual approaches, the promise of liquid biopsies has not yet materialised in the clinic. Widespread deployment requires creative next-generation researchers with an innovative mindset with access to a unique toolbox, including medical know-how, molecular diagnostics expertise (from health economics to regulatory), and statistical/bioinformatical proficiency. Currently, there are no comprehensive training programmes to address this need. To move the promising liquid biopsy technology out of its infancy, the research programme and educational curriculum of the European Liquid Biopsy Academy (ELBA) will cover the entire value chain of diagnostics development and integrate all required disciplines and sectors. ", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-01-01"], "Project_ID": ["765492"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["CENTRO DE INVESTIGACION ECOLOGICA YAPLICACIONES FORESTALES CONSORCIO"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Modelling Tree Response to Aridity Increase with Traits"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["M-TRAIT"], "Technology_Description": "The changes in precipitation patterns that are projected for the coming decades are expected to increase the frequency and intensity of droughts. Despite the potentially dramatic impacts on wood and forest-based ecosystem services, the effect of these changes in the hydrological cycle on European forests is still highly uncertain. One reason for this gap in the knowledge is the inadequacy of the tools currently used to address large-scale land-atmosphere processes at continental scales, the land surface models (LSMs). Indeed, the predictive power of LSMs is hampered by their heavy parameterization of empirical hydrological modules, with parameters fixed per broad plant type irrespective of the environmental conditions. This representation is contradictory to the ecological processes of acclimation and selection and makes the LSMs unsuitable outside of their calibration range especially under extreme conditions. Ecologists have now made progress in describing traits \u2013 tree characteristics that define plant growth strategies. Plant traits vary as much within species as between species, as individuals and communities adapt to their environmental conditions.", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2018-02-01"], "Project_ID": ["747646"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CENTRO DE INVESTIGACION ECOLOGICA YAPLICACIONES FORESTALES CONSORCIO", "Arizona Board of Regents"], "EU_Contribution": ["EUR 239 191,20"], "Project_Title": ["Differential adaptation capacity of dryland grasses to directional changes in water availability (DIAGRASS)."], "Total_Cost": ["EUR 239 191,20"], "Country": ["Spain", "United States"], "Project_ACR": ["DIAGRASS"], "Technology_Description": "Understanding how the intensification of the water cycle, as projected by several climate models, will impact grassland ecosystems will be critical for evaluating their future capacity to provide services and for developing sustainable management policies. This will be especially important in dryland regions, where water availability is the main driver of many ecological processes. To date, several studies have detected responses of vegetation to extreme events from molecular to regional scales, although the heritability of these effects is still unclear. In addition, environmental stresses suffered by a generation can influence the phenotype and performance of its offspring beyond the effects of the transmitted genes (the so-called transgenerational effect). Nevertheless, the description of the mechanisms involved in these responses is also incomplete. The lack of knowledge about the adaptation thresholds of species to new climate scenarios can hamper our ability to predict shifts in ecosystem services. Therefore, the main objective of this project is to evaluate the adaptation capacity of dryland grass species to extreme scenarios of water availability. We will use short- and long-term rainfall manipulative experiments combined with molecular (genomic, genetic and epigenetic), physiological, morphological and ecosystem approaches. The research outlined in this proposal includes a range of state-of-the-art methods to ensure the maximum utility and impact of our results. Altogether, DIAGRASS aims to explore linkages from molecular to ecosystem processes to improve our ability to predict how more extreme rainfall regimes will affect future key ecosystem services (e.g., the stocking-density capacity) of grasslands located in dryland regions. This project will also contribute to improve the knowledge in a key scientific topic for the EU: the Horizon 2020 societal challenge \u201cClimate action, environment, resource efficiency and raw materials\u201d.", "To": ["2021-03-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2018-04-01"], "Project_ID": ["746838"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET", "WAGENINGEN UNIVERSITY", "NAICONS SRL", "THE UNIVERSITY OF WARWICK", "OXFORD DRUG DESIGN LIMITED", "LATVIJAS ORGANISKAS SINTEZES INSTITUTS", "UNIVERSIDAD COMPLUTENSE DE MADRID", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "UNIVERSITEIT GENT", "Statens Serum Institut"], "EU_Contribution": ["EUR 3 445 596,72"], "Project_Title": ["Combatting Antimicrobial Resistance Training Network"], "Total_Cost": ["EUR 3 445 596,72"], "Country": ["Denmark", "Netherlands", "Italy", "United Kingdom", "United Kingdom", "Latvia", "Spain", "Spain", "Belgium", "Denmark"], "Project_ACR": ["CARTNET"], "Technology_Description": "CARTNET trains young researchers in Europe to address serious and global problems of antibiotic resistance. Disease-causing bacteria are becoming resistant even to last resort antibiotics and transmission of resistance genes and resistant pathogens is widespread between human, animal and environmental reservoirs. Therefore, CARTNET will focus on alternative approaches to handle antibiotic resistance and treating resistant infections in both humans and animals. It will provide competences to young researchers and future policymakers that will allow them to use knowledge at all relevant scientific levels and in collaboration with stakeholders in both human and veterinary medicine as well as in chemistry, structural biology and natural product chemistry to develop new antimicrobial solutions. CARTNET comprises researchers who are leading experts on antibiotic resistance and antimicrobial drug discovery. They will in cooperation with the recruited early stage research (ESR) trainees use structural biology to synthesize new antimicrobials, screen environmental microorganisms and microbiota for new active compounds and limit spread of resistance through knowledge of dissemination of mobile genetic elements. The research training is hosted by universities with a strong track record of graduate training and is composed of an ambitious scientific program flanked by essential generic training courses and with ample opportunity for networking at network meetings, conferences and shared secondments. In addition to training young researchers for the challenges of tomorrow CARTNET will from day one provide excellent research with impressive scientific and societal impact.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["765147"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["KING'S COLLEGE LONDON", "OSLO UNIVERSITETSSYKEHUS HF", "FEOPS NV", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "UNIVERSITEIT MAASTRICHT", "UNIVERSIDAD DE ZARAGOZA", "UNIVERSITE DE BORDEAUX", "CONSORCI INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER", "GE VINGMED ULTRASOUND AS", "MEDTRONIC BAKKEN RESEARCH CENTER B.V."], "EU_Contribution": ["EUR 4 000 569,48"], "Project_Title": ["Personalised In-Silico Cardiology"], "Total_Cost": ["EUR 4 000 569,48"], "Country": ["United Kingdom", "Norway", "Belgium", "United Kingdom", "Netherlands", "Spain", "France", "Spain", "Norway", "Netherlands"], "Project_ACR": ["PIC"], "Technology_Description": "Improving healthcare systems mandates a shift towards personalised and preventive management of disease. Specifically, the management of cardiovascular diseases has a huge impact on European society in terms of mortality, morbidity and healthcare costs, being responsible for 1.9 million deaths in the EU annually (42% of all deaths) with a total cost of \u20ac169 billion.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-09-01"], "Project_ID": ["764738"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["MAX PLANCK INSTITUT FUER KOHLENFORSCHUNG", "MAX PLANCK INSTITUT FUER KOHLENFORSCHUNG"], "EU_Contribution": ["EUR 1 485 000"], "Project_Title": ["Shuttle Catalysis for Reversible Molecular Construction"], "Total_Cost": ["EUR 1 485 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["ShuttleCat"], "Technology_Description": "Homogeneous catalysis is one of the pillars of modern chemical synthesis because it enables the sustainable preparation of molecules that find applications in medicinal chemistry, agrochemistry, and materials science. However, many catalytic reactions use hazardous reagents, are unpractical on laboratory-scale or limited in scope. Moreover, while a relatively broad set of catalytic reactions are available to construct chemical bonds, methods to cleave those, which could find applications in biomass and waste valorization, are rare. ", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["757608"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["AALTO-KORKEAKOULUSAATIO", "AALTO-KORKEAKOULUSAATIO"], "EU_Contribution": ["EUR 1 411 258"], "Project_Title": ["Novel Algorithmic Techniques through the Lens of Combinatorics"], "Total_Cost": ["EUR 1 411 258"], "Country": ["Finland", "Finland"], "Project_ACR": ["ALGOCom"], "Technology_Description": "Real-world optimization problems pose major challenges to algorithmic research. For instance, (i) many important problems are believed to be intractable (i.e. NP-hard) and (ii) with the growth of data size, modern applications often require a decision making under {\\em incomplete and dynamically changing input data}. After several decades of research, central problems in these domains have remained poorly understood (e.g. Is there an asymptotically most efficient binary search trees?) Existing algorithmic techniques either reach their limitation or are inherently tailored to special cases. ", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["759557"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["FORSCHUNGSZENTRUM JULICH GMBH", "FORSCHUNGSZENTRUM JULICH GMBH"], "EU_Contribution": ["EUR 1 498 125"], "Project_Title": ["Light-controlled synthetic enzyme cascades"], "Total_Cost": ["EUR 1 498 125"], "Country": ["Germany", "Germany"], "Project_ACR": ["LightCas"], "Technology_Description": "There is an urgent need for the development of greener syntheses procedures if mankind wants to maintain an environment worth living in but is at the same time unwilling to accept a reduction in material comfort. The establishment of more biocatalytic steps in chemical syntheses is one possible solution, as enzymes and whole cells offer sustainable advantages, such as biodegradability, intoxicity, high selectivity, and many more. As a myriad of enzymatic reactions exist for almost any product, their potential is immense. Great scientific achievements and new techniques recently developed have enabled the design of economically and ecologically feasible multi-step enzyme cascades. However, with these new opportunities, also new challenges arise. The more enzyme steps are combined in one pot, the higher the risk of undesired cross-reactivity is. There is thus an urgent need for a tight control of each biocatalytic step in a cascade in order to obtain the desired product in a high purity and to make use of all advantages that enzyme cascades intrinsically offer. With LightCas, I aim to break new grounds in the area of multi-step (bio)catalysis by enabling an orthogonal, selective and thus flexible on/off tuning of enzymes in a cascade. By entrapping enzymes into light-switchable microgels, using photo-switchable active site lids and light-induced enzyme deactivation, three methods providing the opportunity to control enzyme activity in vitro and in vivo on demand will be (further) developed. The ultimate goal is to set up a one-pot multi-step light-controlled enzyme reactor yielding the desired product in high selectivity and concentration in a technically self-regulated manner.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["757320"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["LUONNONVARAKESKUS", "LUONNONVARAKESKUS"], "EU_Contribution": ["EUR 1 814 610"], "Project_Title": ["Towards Understanding the Impact of Climate Change on Eurasian Boreal Forests: a Novel Stable Isotope Approach"], "Total_Cost": ["EUR 1 814 610"], "Country": ["Finland", "Finland"], "Project_ACR": ["ISOBOREAL"], "Technology_Description": "The vast boreal forests play a critical role in the carbon cycle. As a consequence of increasing temperature and atmospheric CO2, forest growth and subsequently carbon sequestration may be strongly affected. It is thus crucial to understand and predict the consequences of climate change on these ecosystems. Stable isotope analysis of tree rings represents a versatile archive where the effects of environmental changes are recorded. The main goal of the project is to obtain a better understanding of \u03b413C and \u03b418O in tree rings that can be used to infer the response of forests to climate change. The goal is achieved by a detailed analysis of the incorporation and fractionation of isotopes in trees using four novel methods: (1) We will measure compound-specific \u03b413C and \u03b418O of leaf sugars and (2) combine these with intra-annual \u03b413C and \u03b418O analysis of tree rings. The approaches are enabled by methodological developments made by me and ISOBOREAL collaborators (Rinne et al. 2012, Lehmann et al. 2016, Loader et al. in prep.). Our aim is to determine \u03b413C and \u03b418O dynamics of individual sugars in response to climatic and physiological factors, and to define how these signals are altered before being stored in tree rings. The improved mechanistic understanding will be applied on tree ring isotope chronologies to infer the response of the studied forests to climate change. (3) The fact that \u03b418O in tree rings is a mixture of source and leaf water signals is a major problem for its application on climate studies. To solve this we aim to separate the two signals using position-specific \u03b418O analysis on tree ring cellulose for the first time, which we will achieve by developing novel methods. (4) We will for the first time link the climate signal both in leaf sugars and annual rings with measured ecosystem exchange of greenhouse gases CO2 and H2O using eddy-covariance techniques.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Finland"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["755865"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM", "ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM"], "EU_Contribution": ["EUR 149 938"], "Project_Title": ["ErasmusBlink: A low cost and easy to use measurement system for medical research with diagnostic potential"], "Total_Cost": ["EUR 149 938"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["ErasmusBlink"], "Technology_Description": "Neuroscientists and clinicians use a wide range of behavioral tests to investigate the physiological mechanisms of learning and memory formation. One of the most objective and reliable tests is eyeblink conditioning, as it is extremely simple, it can be done in both humans and animals, it measures many aspects of how we learn in our daily life, and it can detect memory deficits in many neurological and psychiatric diseases. However, so far there are no low-cost reliable eyeblink conditioning setups commercially available. Therefore, we propose for this ERC-POC application to prepare the commercialization of ErasmusBlink as a low-cost, wearable eyeblink conditioning recording and analysis setup that can be used in virtually all species. With ErasmusBlink one can do reliable and reproducible eyeblink conditioning experiments for scientific, medical and industrial purposes. ErasmusBlink will be the first \u2018total care\u2019 package, alleviating the potential customer from the requirement of the technical and programming skills, which one currently needs to acquire before being able to do eyeblink conditioning experiments. Our market survey will cover three major fields: Basic neurosciences (1), clinical and pharmaceutical research (2), and nutritional sciences (3). For all three fields eyeblink conditioning parameters have been shown to uncover important and fundamental functional processes and correlations. Our current academic collaborations with key players in each of these disciplines and with industrial partners like Noldus IT serve as a solid platform to ensure a successful commercialization of ErasmusBlink.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["737619"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["UNIVERSITAT LINZ", "UNIVERSITAT LINZ"], "EU_Contribution": ["EUR 1 499 975"], "Project_Title": ["Smart HydroGEL SYStems \u2013 From Bioinspired Design to Soft Electronics and Machines"], "Total_Cost": ["EUR 1 499 975"], "Country": ["Austria", "Austria"], "Project_ACR": ["GEL-SYS"], "Technology_Description": "Hydrogels evolved as versatile building blocks of life \u2013 we all are in essence gel-embodied soft machines. Drawing inspiration from the diversity found in living creatures, GEL-SYS will develop a set of concepts, materials approaches and design rules for wide ranging classes of soft, hydrogel-based electronic, ionic and photonic devices in three core aims.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["757931"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["FREIE UNIVERSITAET BERLIN", "FREIE UNIVERSITAET BERLIN"], "EU_Contribution": ["EUR 1 491 487"], "Project_Title": ["Neural mechanism underlying vocal interactions in duetting nightingales"], "Total_Cost": ["EUR 1 491 487"], "Country": ["Germany", "Germany"], "Project_ACR": ["MIDNIGHT"], "Technology_Description": "Humans and many animals produce complex vocal sequences in order to communicate with each other. What are the neuronal mechanisms that integrate the auditory information and permit the production of a coordinated motor response during a vocal interaction? I will address this issue in the nightingale, a songbird species that is capable of duetting with rivals. During vocal interactions, nightingales have to precisely alternate between singing and listening, and I will test whether premotor centers are differentially sensitive to auditory input during these two states. In zebra finches, I have shown that the impact of a father\u2019s song on premotor circuitry can be regulated by inhibitory interneurons during developmental song learning. Here I ask whether this same regulation of auditory input can rapidly change to support real-time vocal coordination in a duetting songbird.", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["757459"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 998 250"], "Project_Title": ["Brain computer interface to study and manipulate mamories of aversive experience during sleep"], "Total_Cost": ["EUR 1 998 250"], "Country": ["France", "France"], "Project_ACR": ["MNEMOSYNE"], "Technology_Description": "The aim of this project is to study the influence of sleep in the establishment of aversive memory and to propose a proof of concept for the use of brain-computer interfaces during sleep to treat pathologies associated with fear or anxiety such as post-traumatic stress disorders. ", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-10-01"], "Project_ID": ["726169"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["ECOLE CENTRALE DE MARSEILLE", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.", "UNIVERSITY OF NORTHUMBRIA AT NEWCASTLE", "CESKE VYSOKE UCENI TECHNICKE V PRAZE", "UNIVERSIDAD DE LAS PALMAS DE GRAN CANARIA", "OZYEGIN UNIVERSITESI", "INSTITUTO DE TELECOMUNICACOES", "OSRAM GMBH", "INDRA SISTEMAS SA", "OLEDCOMM SAS", "FORD OTOMOTIV SANAYI ANONIM SIRKETI"], "EU_Contribution": ["EUR 3 752 913,96"], "Project_Title": ["European Training Network on Visible light based Interoperability and Networking"], "Total_Cost": ["EUR 3 752 913,96"], "Country": ["France", "Germany", "United Kingdom", "Czech Republic", "Spain", "Turkey", "Portugal", "Germany", "Spain", "France", "Turkey"], "Project_ACR": ["VisIoN"], "Technology_Description": "New generations of LEDs have attractive features such as a long life expectancy, lower power consumption and reduced heat dissipation. In line with governmental plans worldwide, it is predicted that LEDs will be the ultimate light source in the near future. Besides indoor illumination, LEDs are being widely used in street lighting, traffic signs, advertising displays, transportation, etc. Visible light communication (VLC) is one of the most promising current areas of research with a significant potential for high-impact results, and successful outcomes might revolutionize utilization of LEDs for modern infrastructures to add novel functionalities in addition to illumination. VLC has been proposed for smart homes and streets, manufacturing and medical environments for increased data security and reduced interference, or a two-way vehicle-to-vehicle and vehicle-to-roadside infrastructure communications as part of the emerging intelligent transportation systems for increasing road safety. The proposed \u201cEuropean Training Network on Visible-light based Interoperability and Networking (VisIon)\u201d aims to train a new generation of early-stage researchers (ESRs) in the emerging area of VLC. Through research on co-supervised individual projects focusing on selected applications, VisIon will make significant contributions to the fundamental scientific understanding and technical knowhow. Targeted application areas include indoor and outdoor VLC access, smart transportation, and medical and manufacturing environments. In addition to technical training through PhD courses, dedicated tutorials and workshops organized by the Network, the ESRs will benefit from a wide range of complementary non-technical training activities such as entrepreneurship, authoring scientific papers/patents, dissemination, etc. The participation of industrial partners will further promote research training with commercialisation perspectives enabling ESRs to fully integrate theory with hands-on practice.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Jiri Matas", "Tel.: +420 22435721", "Fax: +420 224357385", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-09-01"], "Project_ID": ["764461"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET", "KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 149 986"], "Project_Title": ["GPCR Exploitation To Unlock the Power of Brown/Beige Adipose Tissue"], "Total_Cost": ["EUR 149 986"], "Country": ["Denmark", "Denmark"], "Project_ACR": ["GET-UP BAT"], "Technology_Description": "Hundreds of millions of people suffer from obesity and diabetes worldwide. These diseases diminish both life quality and expectancy and new treatment strategies are desperately needed. One possible approach is to target the calorie-burning and glucose-consuming functions of brown and beige adipose tissue (B/BAT). Previous attempts to harness the therapeutic potential of B/BAT have largely focused on the \u03b2-adrenergic class of G protein-coupled receptors (GCPRs). Unfortunately, these methods are hindered by adverse cardiovascular side effects linked to adrenergic activation. Therefore, uncovering non-adrenergic alternatives to exploit B/BAT for treating metabolic disease holds the potential for enormous societal and economic benefit.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["768783"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET", "KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 1 761 190"], "Project_Title": ["How do infants mentalize? Bringing a neuroimaging approach to the puzzle of early mindreading."], "Total_Cost": ["EUR 1 761 190"], "Country": ["Denmark", "Denmark"], "Project_ACR": ["DEVOMIND"], "Technology_Description": "Human social interaction and learning depends on making the right inferences about other people\u2019s thoughts, a process commonly called mentalizing, or Theory of Mind, a cognitive achievement which several decades of research concluded was reached at around age 4. The last 10 years has radically changed this view, and innovative new paradigms suggest that even preverbal infants can think about others\u2019 minds. This new developmental data has created arguably one of the biggest puzzles in the history of developmental science: How can infants be mentalizing when years of research have shown that a) pre-schoolers fail at mentalizing tasks and b) mentalizing depends on the development of cognitive control, language, and brain maturation? The key issue is whether behaviour that looks like infant mentalizing really is mentalizing, or might infants\u2019 success belie alternative processes? The most powerful strategy for resolving this puzzle is to look to brain activity. By applying the same methods and paradigms across infancy and early childhood, DEVOMIND will investigate whether infants\u2019 success on mentalizing tasks recruits the same network of brain regions, and neural processes, that we know are involved in success in older children and adults. In the second half of the project, we will use our neural indicators of mentalizing to test a completely novel hypothesis in which infants\u2019 success is possible because they have a limited ability to distinguish self from other. Although novel, this hypothesis deserves to be tested because it has the potential to explain both infants\u2019 success and preschoolers\u2019 failures under a single, unified theory. By bringing a neuroimaging approach to the puzzle of early mentalizing, DEVOMIND will allow us to move beyond the current impasse, and to generate a new theory of Theory of Mind.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["726114"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["The Socialization of Private Sector Elites in Kenya"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SOPRISEKEN"], "Technology_Description": "SOPRISEKEN focuses on the sociability of professional and managerial elites in modern Kenya. Studying socialization, and in particular the membership organizations in which it takes place, is a particularly fruitful way to understand how these elites have experienced the social and economic changes triggered in Africa by the \u201cstructural adjustment\u201d policies of the 1980s; how they have come to understand themselves as a distinct social group - the \u201cprivate sector\u201d - sharing comparable social aspirations, lifestyle and economic ethos; and how the articulation of their interests has led to the development of similar civic and political attitudes.", "To": ["2019-04-30, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["749372"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["VYSOKE UCENI TECHNICKE V BRNE", "UNIVERSITAET STUTTGART", "Asociacion - Centro de Investigacion Cooperativa en Nanociencias - CIC NANOGUNE", "THOMAS KEATING LIMITED"], "EU_Contribution": ["EUR 2 898 683,75"], "Project_Title": ["Plasmon Enhanced Terahertz Electron Paramagnetic Resonance"], "Total_Cost": ["EUR 2 898 683,75"], "Country": ["Czech Republic", "Germany", "Spain", "United Kingdom"], "Project_ACR": ["PETER"], "Technology_Description": "We propose to establish Plasmon-enhanced Terahertz Electron Paramagnetic Resonance spectroscopy and scanning microscopy as a unique Electron Paramagnetic Resonance (EPR) platform for high-sensitivity local analysis of paramagnetic organic and inorganic species and materials. Here, we will deliver novel hardware and infrastructure providing ground-breaking innovation in the magnetic sensing and imaging. The platform is conceptually based on incorporating THz plasmonic antennas onto surfaces (spectroscopy) and scanning probe tips (microscopy), resulting in a strong, local enhancement (about two orders of magnitude) of the magnetic sensing field. ", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-01-2016-2017 - FET-Open research and innovation actions"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Czech Republic"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-01-01"], "Project_ID": ["767227"], "Call_for_Proposal": ["H2020-FETOPEN-1-2016-2017"]}, -{"Partners": ["Academisch Medisch Centrum bij de Universiteit van Amsterdam", "STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN", "SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO SANT'ANNA", "TECHNISCHE UNIVERSITEIT EINDHOVEN", "DUALIS MEDTECH GMBH", "XELTIS BV"], "EU_Contribution": ["EUR 3 035 550"], "Project_Title": ["Development of the first fully biocompatible, soft actuated heart: combining in situ tissue engineering and soft robotics"], "Total_Cost": ["EUR 3 035 550"], "Country": ["Netherlands", "Netherlands", "Italy", "Netherlands", "Germany", "Netherlands"], "Project_ACR": ["HybridHeart"], "Technology_Description": "The Hybrid Heart consortium envisions to develop and bring to the clinic soft biocompatible artificial organs. These will consist of a soft robotics shell with actuators (\u2018artificial muscles\u2019) and sensors, enabling completely natural motion. The inner lining and structures will be made by in situ tissue engineering (TE), ensuring biocompatibility of blood-contacting surfaces.", "To": ["2022-10-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-01-2016-2017 - FET-Open research and innovation actions"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-11-01"], "Project_ID": ["767195"], "Call_for_Proposal": ["H2020-FETOPEN-1-2016-2017"]}, -{"Partners": ["ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON", "THE UNIVERSITY OF MANCHESTER", "SCHWEIZERISCHES FORSCHUNGSINSTITUT FUER HOCHGEBIRGSKLIMA UND MEDIZIN IN DAVOS", "IDRYMA IATROVIOLOGIKON EREUNON AKADEMIAS ATHINON", "UNIVERSYTET MEDYCZNY W LODZI.", "UMEA UNIVERSITET", "GIORGI ELIAVA INSTITUTE OF BACTERIOPHAGY, MICROBIOLOGY AND VIROLOGY", "ELIAVA BIO PREPARATIONS LTD", "EUROPEAN FEDERATION OF ASTHMA &ALLERGY ASSOCIATIONS IDEELL FORENING", "MARIOS LYMARAKIS KAI SIA EE"], "EU_Contribution": ["EUR 2 971 750"], "Project_Title": ["Constructing a \u2018Eubiosis Reinstatement Therapy\u2019 for Asthma"], "Total_Cost": ["EUR 2 971 750"], "Country": ["Greece", "United Kingdom", "Switzerland", "Greece", "Poland", "Sweden", "Georgia", "Georgia", "Belgium", "Greece"], "Project_ACR": ["CURE"], "Technology_Description": "The asthma pandemic imposes a huge burden on patients and health systems in both developed and developing countries. Notwithstanding major efforts in untangling its pathophysiology, we are not even close to reaching a cure. Despite available treatments, symptom control is generally suboptimal and hospitalisations and deaths remain at unacceptably high levels. This calls for disruptive innovation towards a long-term treatment strategy. Asthma is an inflammatory condition associated with immune deviations, most often atopic allergy. However, a key characteristic of asthma that remains relatively unexplored is susceptibility to infection. Most acute asthma attacks follow upper respiratory infections; infections are also associated with asthma initiation and persistence. Recent studies reveal that the respiratory microbiome is characteristically imbalanced (dysbiotic) in asthma. Our own data indicate that a feature of dysbiosis in asthma is reduced abundance of bacteriophages (phages). These bacterial viruses infect and are able to naturally control bacterial populations. Phage therapy has been grossly neglected in the western world and is currently just appearing as a novel tool against infection. However, it has never been used for rebalancing dysbiosis in humans.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-01-2016-2017 - FET-Open research and innovation actions"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Greece"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-10-01"], "Project_ID": ["767015"], "Call_for_Proposal": ["H2020-FETOPEN-1-2016-2017"]}, -{"Partners": ["CONSIGLIO NAZIONALE DELLE RICERCHE", "FORSCHUNGSZENTRUM JULICH GMBH", "FEI ELECTRON OPTICS BV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "UNIVERSITY OF GLASGOW", "QED FILM & STAGE PRODUCTIONS LTD", "UNIVERSITA DEGLI STUDI DI MODENA E REGGIO EMILIA", "UNIVERSITEIT MAASTRICHT"], "EU_Contribution": ["EUR 2 997 675"], "Project_Title": ["QUANTUM SORTER"], "Total_Cost": ["EUR 2 997 675"], "Country": ["Italy", "Germany", "Netherlands", "Germany", "United Kingdom", "United Kingdom", "Italy", "Netherlands"], "Project_ACR": ["Q-SORT"], "Technology_Description": "Q-SORT introduces a revolutionary concept whereby the TEM is employed as a Quantum Sorter. All TEM techniques are in fact limited to the imaging and energy spectroscopy of the electron wavefunction. Moreover, when a single sample property is sought, most of the image information is useless, a waste that cannot be afforded in dose-sensitive materials. The Quantum Sorter leverages the recently-acquired capacity to structure e-beams, which implies that if, in a quantum experiment (tunable state preparation, interaction, analysis), the analysis is performed over the \u2018optimal\u2019 basis of quantum states, very few electrons are necessary for the full characterisation of a sought property, i.e. the TEM can be tuned to answer a single question but with maximum efficiency. To this end, Q-SORT introduces a new parallel analysis strategy, based on a suitable conformal mapping of the wavefunction: the starting point is the analysis of orbital angular momentum (OAM), but building a recipe for diagonalising a wider range of observables is one of the planned Breakthroughs of Q-SORT. This will in turn allow Q-SORT to achieve three other high-risk Breakthroughs of vast applicability: assessing the OAM of plasmonic resonances in select nanoparticles, achieving atomic-resolution magnetic dichroism, identifying different proteins based on selected properties. We believe that the Quantum Sorter will become so important that it will eventually be part of every state-of-the-art TEM, since the new technology is easy to integrate with energy-loss spectrometry. The project consortium includes some of the world leaders in optical and electronic vortex beams, as well as in protein cryoTEM. A major industrial partner in TEM is included, so as to secure market penetration of technological outcomes. The project avails itself of established resource and IPR management techniques. Gender balance and equal opportunities will be ensured. A comprehensive outreach and dissemination strategy is foreseen.", "To": ["2021-03-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-01-2016-2017 - FET-Open research and innovation actions"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["766970"], "Call_for_Proposal": ["H2020-FETOPEN-1-2016-2017"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI TRIESTE", "AARHUS UNIVERSITET", "ISTITUTO NAZIONALE DI FISICA NUCLEARE", "OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN", "THE QUEEN'S UNIVERSITY OF BELFAST", "TECHNISCHE UNIVERSITEIT DELFT", "UNIVERSITY COLLEGE LONDON", "UNIVERSITY OF SOUTHAMPTON", "M-SQUARED LASERS LIMITED"], "EU_Contribution": ["EUR 4 371 473,75"], "Project_Title": ["Testing the Large-Scale Limit of Quantum Mechanics"], "Total_Cost": ["EUR 4 371 473,75"], "Country": ["Italy", "Denmark", "Italy", "Austria", "United Kingdom", "Netherlands", "United Kingdom", "United Kingdom", "United Kingdom"], "Project_ACR": ["TEQ"], "Technology_Description": "Microscopic systems can be prepared in quantum configurations with no classical counterpart. Such a possibility seems precluded when the 'complexity' of the system grows towards the macroscopic domain: so far we have no evidence of non-classical behavior of the macroscopic world. Why is it so? How is quantumness lost as we abandon the microscopic domain? These questions, which remain to date largely unanswered, address interesting and challenging goals of modern research in physics, and serve the overarching goal of this project. TEQ will establish the large-scale limit of quantum mechanics by pursuing a novel research programme that aims at surpassing the current approach based on matter-wave interferometry. Specifically, the TEQ Consortium will", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-01-2016-2017 - FET-Open research and innovation actions"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-01-01"], "Project_ID": ["766900"], "Call_for_Proposal": ["H2020-FETOPEN-1-2016-2017"]}, -{"Partners": ["UNIVERSITAETSKLINIKUM HAMBURG-EPPENDORF", "EBERHARD KARLS UNIVERSITAET TUEBINGEN", "KUNGLIGA TEKNISKA HOEGSKOLAN", "ACADEMISCH ZIEKENHUIS LEIDEN", "SYDDANSK UNIVERSITET", "LUDGER LTD", "RIJKSUNIVERSITEIT GRONINGEN", "UNIVERSITETET I OSLO", "UNIVERSITAET FUER BODENKULTUR WIEN", "ALPHALYSE A/S", "HEXAL AKTIENGESELLSCHAFT"], "EU_Contribution": ["EUR 3 933 617,40"], "Project_Title": ["Analytics for Biologics"], "Total_Cost": ["EUR 3 933 617,40"], "Country": ["Germany", "Germany", "Sweden", "Netherlands", "Denmark", "United Kingdom", "Netherlands", "Norway", "Austria", "Denmark", "Germany"], "Project_ACR": ["A4B"], "Technology_Description": "Qualitative and quantitative analysis and purification of therapeutic protein species (TP-S) \u2013 coded by the same gene, thus chemically often very similar \u2013 is one of the most challenging problems in analytical chemistry today. This problem is of huge impact in the area of therapeutic proteins (TPs) \u2013 a rapidly growing market \u2013 causing a high demand in specialists in the field of TP manufacturing. This demand can currently not be met by single European universities. In an Europe-wide joint research and training network the graduate school A4B will offer a specific training program yielding the required specialists. A4B-PhD students will develop solutions for the most urgent problems in TP production and analysis. ", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-10-01"], "Project_ID": ["765502"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["ASSOCIACAO DO INSTITUTO SUPERIOR TECNICO PARA A INVESTIGACAO E DESENVOLVIMENTO", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "INSTITUT JOZEF STEFAN", "CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL", "SOFIISKI UNIVERSITET SVETI KLIMENT OHRIDSKI", "CHARGE2C-NEWCAP LDA"], "EU_Contribution": ["EUR 3 764 276,25"], "Project_Title": ["Plasma Enabled and Graphene Allowed Synthesis of Unique nano Structures"], "Total_Cost": ["EUR 3 999 633,75"], "Country": ["Portugal", "France", "Slovenia", "Germany", "Bulgaria", "Portugal"], "Project_ACR": ["PEGASUS"], "Technology_Description": "\"PEGASUS ultimate goal is to create a highly efficient, catalyst/harmful-free novel plasma method along with a proof-of-concept PEGASUS device for a large-scale N-graphene direct synthesis, as well as N-graphene/MnO2/Fe2O3/SnO2 composites and unique vertical N-graphene arrays grown on metal substrates, via breakthrough research on plasma-enabled singular assembly pathways. By doing so, a disruptive and highly competitive alternative to conventional lengthy/multistep routes will emerge, based on the mastering of plasma exclusive mechanisms to control the amount and localization of energy and matter at atomic scales, spurring a new European manufacturing/processing platform. The envisioned path will prompt and build on ground-breaking developments in the underlying physics, with the resulting processes embodying invaluable economic/social impact potential. PEGASUS framework is uniquely positioned to succeed and raise the Europe competitiveness in the strategic nano synthesis domain via the promotion of plasma methods as a Key Enabling Technology for highly controllable and \"\"green\"\" assembly of atom-thick hybrid nanostructures and by replacing long existing materials with new cost-effective, higher performance ones. The synergy between plasma physics and mechanical, electrochemical and hi-tech engineering expertise will be the driving force boosting the innovative approach pursued by this project, spanning from fundamental knowledge to appliance prospects. Internationally recognized scientists will contribute to this interdisciplinary project, triggering the commercialization of novel materials and delivering proof-of-concept PEGASUS and supercapacitor devices. With a science-devoted team lead by a female coordinator, PEGASUS contribution ambitions go beyond the scientific scope, helping to bridge economical/social gaps in tune with the EU ambitions.\"", "To": ["2021-10-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-01-2016-2017 - FET-Open research and innovation actions"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Portugal"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-11-01"], "Project_ID": ["766894"], "Call_for_Proposal": ["H2020-FETOPEN-1-2016-2017"]}, -{"Partners": ["Academisch Medisch Centrum bij de Universiteit van Amsterdam", "INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE", "KAROLINSKA INSTITUTET", "THE BABRAHAM INSTITUTE", "IFOM FONDAZIONE ISTITUTO FIRC DI ONCOLOGIA MOLECOLARE", "ANAXOMICS BIOTECH, S.L.", "Redoxis AB", "HELMHOLTZ-ZENTRUM FUER INFEKTIONSFORSCHUNG GMBH", "IBM RESEARCH GMBH", "ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS"], "EU_Contribution": ["EUR 3 605 245,20"], "Project_Title": ["COmbatting disorders of adaptive immunity with Systems MedICine"], "Total_Cost": ["EUR 3 605 245,20"], "Country": ["Netherlands", "France", "Sweden", "United Kingdom", "Italy", "Spain", "Sweden", "Germany", "Switzerland", "Greece"], "Project_ACR": ["COSMIC"], "Technology_Description": "Background: EU countries face large health challenges to combat chronic diseases. Recently, systems medicine has emerged as a promising discipline to accelerate the translation of basic research into applications for improved diagnostics and personalized treatment. Its power arises from the integration of laboratory and computational approaches crossing research disciplines and sectors to solve clinical questions. COSMIC delivers the next generation of leading, entrepreneurial, and innovative systems medicine professionals having expertise, skills, and experience to successfully combat complex human disorders. These professional will find excellent career opportunities. COSMIC focuses on B-cell neoplasia and rheumatoid arthritis, prototypical diseases originating from abnormal functioning of immune cells, often resulting in similar antigen specificities. COSMIC enables Early Stage Researchers to play a leading role in this exciting field.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["765158"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["Academisch Medisch Centrum bij de Universiteit van Amsterdam", "REGION NORDJYLLAND (NORTH DENMARK REGION)", "OPTIMEDIS AG", "UNIVERSITY OF SURREY", "SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO SANT'ANNA", "BUDAPESTI CORVINUS EGYETEM"], "EU_Contribution": ["EUR 3 355 245"], "Project_Title": ["Healthcare Performance Intelligence Professionals"], "Total_Cost": ["EUR 3 355 245"], "Country": ["Netherlands", "Denmark", "Germany", "United Kingdom", "Italy", "Hungary"], "Project_ACR": ["HealthPros"], "Technology_Description": "Balancing between improving population health, delivering quality care for individuals, and containing costs is a timely social/economical challenge in Europe. There is great potential achieving this through healthcare (HC) system performance intelligence optimizing effective use of available HC data in countries. Effective implementation of HC performance intelligence (HPI) by skilled professionals will improve integrated service delivery; patient engagement; equality in access to HC; health outcomes; and reduce waste in HC. Translating HC data into meaningful, valid, actionable performance intelligence that is transferrable into actions to improve HC systems requires multidisciplinary skills & innovative competencies; currently not well developed in training programmes and the scientific community and missing in today\u2019s European HC market. The ETN for HPI Professionals (HealthPros) fills this gap and directly impacts the European Research Area by training innovative \u201cHealthcare Performance Intelligence Professionals\u201d uniting a multidisciplinary consortium tackling private, public, academic sectors.13 ESRs will be trained in multidisciplinary innovative scientific technical and complementary skills, seconded to private / public / academic HC sectors in multiple countries and build relations with potential future employers. 5 ESRs work on PhD projects related to HC performance measurement optimizing the use of available registry and administrative data and applying statistical models to provide actionable input to HC performance management. 4 ESRs work on PhDs to translate performance intelligence into value-creating HC governance mechanisms; 4 ESRs work on PhDs aimed to impact the actual use of performance intelligence by different end-users. ESRs will have unique HC data access.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["765141"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["QUEEN MARY UNIVERSITY OF LONDON", "CENTRO DE NEUROCIENCIAS E BIOLOGIACELULAR ASSOCIACAO", "UNIVERSITE D'ARTOIS", "KAROLINSKA INSTITUTET", "CENTRO HOSPITALAR E UNIVERSITARIO DE COIMBRA E.P.E.", "HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH", "MJR PHARMJET GMBH", "UNIVERSITAET INNSBRUCK", "THE UNIVERSITY OF WARWICK"], "EU_Contribution": ["EUR 3 590 354,52"], "Project_Title": ["New nanomaterials for neural stem cells drug delivery"], "Total_Cost": ["EUR 3 590 354,52"], "Country": ["United Kingdom", "Portugal", "France", "Sweden", "Portugal", "Germany", "Germany", "Austria", "United Kingdom"], "Project_ACR": ["NANOSTEM"], "Technology_Description": "Brain conditions such as neurodegenerative diseases, stroke and traumatic injuries are a mayor burden in modern society. Because neural stem cells (NSCs) can differentiate into new neural cells including neurons, the regulation of their proliferation, differentiation and migration represent a promising regenerative/therapeutic strategy. The hypothesis of NanoStem project is that novel nanoparticles (NPs) combined with recent identified/developed pharmaceuticals can be an efficient approach to control the biological activity of NSCs. The scientific project is organized in three work packages (WP), each focusing on specific objectives and containing well-defined deliverables. WP1 will focus on the synthesis of the nanomaterials and the uploading of the therapeutics. WP2 will take the best nanoparticles and focus more on the evaluation of the permeation and efficacy of the formulations against NSCs. WP3 will focus on in vivo studies to evaluate the formulations developed to tackle the brain and to assess their toxicity. The project will train 14 ESRs in areas including organic and polymer chemistry, cell biology, pharmacology, neuroscience, nanobiotechnology and clinical sciences. The project will also provide a substantial training program in complementary skills, targeting both professional and personal development, and translation of research and entrepreneurship. The project brings together six academic partners, one hospital and two industrial teams as full partners, complemented by four associate partners, one of which is an industrial team, distributed over a total of seven European Union member states. The consortium brings together groups with a very interdisciplinary expertise ranging from nanoparticle synthesis and characterization, computational modeling, in vitro BBB models and BBB transport, neural stem cells, animal testing and clinical expertise.", "To": ["2022-05-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-06-01"], "Project_ID": ["764958"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["UNIVERSITE GRENOBLE ALPES"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["The origin of the IMF through multi-scale analysis of molecular clouds: unification of PDF and power spectrum analysis"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["Filaments to stars"], "Technology_Description": "The omnipresence of filamentary structures inside nearby molecular clouds observed by the Herschel space observatory challenges our comprehension of the star formation process. We now know that most of the cold dense cores appear to form within those filaments, which suggest a possible link between the characterisation of the filamentary structure of molecular clouds and the core mass function (CMF). Physical processes such as turbulence, gravitational fragmentation and the influence of magnetic field transform the interstellar medium and leave characteristic signatures within the shape of structures. In order to understand the physical processes leading to the formation of filaments and cores in molecular clouds and later to the formation of stars, many statistical tools have been developed to characterise such signatures. Among them there are the probability distribution function (PDF), which form the foundation of many modern theories of star formation, and the power spectrum analysis, which started with the pioneer work of Andrey Kolmogorov and remains our best tool today to analyse and characterise the turbulence. Usually measured independently, I propose in this project to unify both analysis through a multi-scale analysis approach of nearby molecular clouds. In the recent years, I developed wavelet based analysing techniques allowing me to separate the different statistical signatures of physical processes involved in filaments and cores formation. Furthermore, part of these techniques also imply the analysis of linear polarisation allowing a unique multi-scale description of the interstellar magnetic field. The aim of this project is to build a global and coherent picture, based on observations, of how cloud structures and magnetic fields have an impact on the formation of dense cores.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["750920"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["BAR ILAN UNIVERSITY", "UNIVERZITA KARLOVA", "EDINBURGH NAPIER UNIVERSITY", "UNIWERSYTET JAGIELLONSKI", "STICHTING FONTYS", "LINKOPINGS UNIVERSITET", "TAMPEREEN YLIOPISTO", "AGE PLATFORM EUROPE"], "EU_Contribution": ["EUR 3 879 540,72"], "Project_Title": ["An international, multi-disciplinary, multi-sectoral training network on ageism"], "Total_Cost": ["EUR 3 879 540,72"], "Country": ["Israel", "Czech Republic", "United Kingdom", "Poland", "Netherlands", "Sweden", "Finland", "Belgium"], "Project_ACR": ["EuroAgeism"], "Technology_Description": "Europe has the largest percentage of older adults worldwide. Yet, there is a high prevalence of ageism; the complex and often negative construction of old age, in society at large, and among researchers and practitioners in particular. In contrast to the wide prevalence of ageism, the majority of research, to date, has targeted racism and sexism and neglected to address ageism. A similar neglect is found on the policy side, as age is still not an explicit part of a U.N. declaration of human rights. To address these shortcomings, EuroAgeism is focused on harmonising different theoretical and methodological disciplines in the field of ageism. It aims to bring together science and policy by creating an opportunity for a true dialogue that will allow graduates of the program to capture positions as scientists, educators, science advisers, policy advocates, lobbyists, or legislators in the field of ageism. ", "To": ["2021-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other"], "From": ["2017-11-01"], "Project_ID": ["764632"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["THE UNIVERSITY OF SHEFFIELD", "THE UNIVERSITY OF SHEFFIELD"], "EU_Contribution": ["EUR 2 492 201"], "Project_Title": ["Soundscape Indices"], "Total_Cost": ["EUR 2 492 201"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["SSID"], "Technology_Description": "Eighty million EU citizens are suffering from excessive environmental noise and billions of euros are being spent on noise control, under the EU Directive on Environmental Noise. Unfortunately, the conventional approach, i.e. reduction of \u2018sound level\u2019, simply does not deliver the required improvements in quality of life. The growing field of \u2018soundscape studies\u2019 is addressing this gap by considering sound environment as perceived, in context, with an interdisciplinary approach. However, soundscapes are hugely complex and measuring them as a basis for environmental design requires a step change to the discipline. This research aims to achieve a ground-breaking development through the establishment of \u2018soundscape indices\u2019 (SSID), adequately reflecting levels of human comfort, the impact of which will be reminiscent of that of the Decibel scale created by Bell Systems a century ago. This will provide the underpinning science for soundscape in the field of built environment, with wider intellectual goals of moving from noise control to soundscape creation. Key objectives, as coherent steps for achieving the main aim, are: (1) To characterise soundscapes, by capturing soundscapes and establishing a comprehensive database, which will be a cornerstone for the proposed analysis, and an invaluable resource for scientists for years to come. (2) To determine key factors and their influence on soundscape quality based on the database, by conducting laboratory psychological evaluation, physical/psychoacoustic factors analysis, and more importantly, to research at a physiological/biological level, including the use of functional magnetic resonance imaging. (3) To develop, test and validate the soundscape indices, through analysing the influences by various factors, using a number of inter- & trans-disciplinary approaches. (4) To demonstrate the applicability of the soundscape indices in practice, by establishing frameworks for soundscape prediction, design, and standardisation.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["740696"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["BAR ILAN UNIVERSITY", "BAR ILAN UNIVERSITY"], "EU_Contribution": ["EUR 1 499 345"], "Project_Title": ["New Nuclear Medicine Imaging Radiotracer 64Cu(II) for diagnosing Hypoxia Conditions Based on the Cellular Copper Cycle"], "Total_Cost": ["EUR 1 499 345"], "Country": ["Israel", "Israel"], "Project_ACR": ["CuHypMECH"], "Technology_Description": "Imaging of hypoxia is important in many disease states in oncology, cardiology, and neurology. Hypoxia is a common condition encountered within the tumour microenvironment that drives proliferation, angiogenesis, and resistance to therapy. Despite on-going efforts to identify hypoxia, until now there is no clinically approved imaging biomarker, due to both low tumour uptake, and a low signal to background (S/B) ratio that affects the imaging quality. Nuclear Medicine is using labelled radio-isotopes for PET/CT and SPECT imaging. These radio-tracers diagnose the metabolic processes in the body. Among these tracers, 18F-FDG is the most routinely used as a marker of glucose metabolism. However, not all tumours consume glucose, and glucose consumption is not specific only for malignant tumours, which limits its application. Copper is a nutritional metal, recently examined as a radiotracer for hypoxia, owing to its to the oxidising environment. Clinical and in-vivo studies on various 64Cu(II)-PET radiotracers resulted in controversial reports on the specificity of the current tracers for hypoxia imaging due to non-selective bio-distribution & low S/B ratio. This multidisciplinary proposal focuses on the discovery of comprehensive signal pathways of the cellular copper cycle using advanced biophysical methods and a proprietary design of 64Cu(II) radiotracer. This radiotracer will be incorporated in the cellular copper cycle, and will enable to selectively target the oxidising environment in tumours. The design of the new radiotracer is based on systematic structural & functional mapping of the copper binding sites to the various copper proteins and the visualisation of the transfer mechanism. This new copper tracer should increase the selectivity of tumour uptake, stability, and improve bio-distribution. This project assimilates cold and hot chemistry and biology, while emphasising the clinical unmet need in metal based radiotracer that form stable complexes.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["754365"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["AARHUS UNIVERSITET", "KATHOLIEKE UNIVERSITEIT LEUVEN", "UNIVERSITETET I OSLO", "THE UNIVERSITY OF EDINBURGH"], "EU_Contribution": ["EUR 4 167 054"], "Project_Title": ["Anthropology of Human Security in Africa"], "Total_Cost": ["EUR 4 167 054"], "Country": ["Denmark", "Belgium", "Norway", "United Kingdom"], "Project_ACR": ["ANTHUSIA"], "Technology_Description": "ANTHUSIA is a multi-disciplinary EJD in the Anthropology of Human Security in Africa proposed by a consortium of four universities in Aarhus, Edinburgh, Leuven and Oslo. Combining competences from Anthropology, Human Security and African Studies It aims to foster talent relevant to current challenges and potentials of developing safe societies in Africa. By exploring different areas from a human security perspective, the research will provide insights into problems such as expanding young populations, accelerated urbanisation, unequally distributed growth, recurring conflicts, persistent health problems, and refugee insecurity. A human security perspective shifts the focus from the security of nation states to the safety and well-being of humans in their everyday lives. Human security problems, as well as growth rates in Africa have obvious ramifications for European home security and economy. Refugee crises due to human insecurity in the African continent are likely to continue evolving in the future.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EJD - European Joint Doctorates"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["764546"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE", "LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE"], "EU_Contribution": ["EUR 149 973"], "Project_Title": ["Networking and Care: Helping young people with mental health problems through outreach and eHealth"], "Total_Cost": ["EUR 149 973"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["NCore"], "Technology_Description": "The aim of this project is to develop a mobile app which facilitates access to mental health services and treatments for young people with mental health problems; and to assess its feasibility, acceptability and potential clinical and cost-effectiveness. If successful, the app would: (1) increase access to mental health care by providing links to relevant existing services; (2) increase access to relevant evidence-based mobile health interventions and to address barriers to care and (3) allow individuals to review services they have used and provide feedback which can be accessed by other app users.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["737569"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN", "INSTITUT CURIE", "SEMMELWEIS EGYETEM", "UNIVERSITAETSKLINIKUM FREIBURG", "UNIVERSITEIT UTRECHT", "HANSABIOMED LIFE SCIENCES OU", "BIOINF2BIO LDA", "GVS S.P.A.", "AJ Innuscreen GmbH", "UNIVERSITEIT GENT"], "EU_Contribution": ["EUR 3 724 252,20"], "Project_Title": ["Training in Extracellular Vesicles: for benefit in Health and Disease"], "Total_Cost": ["EUR 3 724 252,20"], "Country": ["Ireland", "France", "Hungary", "Germany", "Netherlands", "Estonia", "Portugal", "Italy", "Germany", "Belgium"], "Project_ACR": ["TRAIN-EV"], "Technology_Description": "Exosomes and microvesicles/ectosomes, collectively termed extracellular vesicles (EV), have attracted much recent interest because of their potential functions, use as disease biomarkers and possible therapeutic exploitation. Due to their enormous relevance, this relatively new field of research is quickly expanding. While Europe leads the field of EV research, there are still many gaps in knowledge that need to be addressed to ensure optimal exploitation of EVs from health and Europe\u2019s economic benefit. Addressing this, TRAIN-EV\u2019s objective is to provide excellent and integrated multi-disciplinary and inter-sectoral training of a critical mass of ESRs of outstanding potential in the academic, clinical, and industry/business components of exploiting EV, while performing novel cutting-edge research to address these gaps and generate new knowledge. This will be achieved by appointing 15 ESRs into 10 Beneficiary Organisations (6 academic; 4 non-academic), with 4 additional Partner Organisations (3 non-academic; 1 academic) offering secondments, training and additional networking opportunities. All Participants have highly relevant and complementary medical/science/engineering/business expertise \u2013detailed within\u2013 that will collectively contribute to the training, to PhD level, of these 15 ESRs as academic and industry EV leaders for the future.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["722148"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["VESTAS AIRCOIL AS", "UNIVERSITY OF SOUTHAMPTON"], "EU_Contribution": ["EUR 1 093 151,52"], "Project_Title": ["Integrated Design of Engineering Structures"], "Total_Cost": ["EUR 1 093 151,52"], "Country": ["Denmark", "United Kingdom"], "Project_ACR": ["InDEStruct"], "Technology_Description": "This collaborative doctoral training programme provides a model for the development of technology leaders, enabling them to apply scientific methods from academia to interdisciplinary industrial design. The project is driven by the need for more efficient & lower emission engine systems. Heat exchangers in engines has been identified as a key enabling technology for low-emission power systems that is vital to the EU economy and is of great societal concern. Development of high-performance heat exchangers is a complex engineering challenge requiring academic contributions at the forefront of engineering science, which will enhance the EU\u2019s competitiveness by delivering economically and environmentally improved products. Having identified charge air cooling as a key enabling technology for low-emission power systems, here we propose an integrated approach to doctoral training in the area of engineering design leading to four doctorates covering diverse aspects of their mechanical engineering: structural vibration, stress & thermal analysis, additive manufacturing (AM), multifunctional metamaterials, fatigue & materials development. This project brings together a consortium of industrial and academic partners in a novel and bespoke doctoral training programme that is multi-disciplinary in its content and inter-sectoral with regards to the employability of the technology leaders of tomorrow. The programme provides a coherent training platform that inherently nurtures technical, creative and entrepreneurial skills. The central theme of Engineering Design within the programme enables us to build a training structure which is technically broad yet scientifically rigorous, while having the academic depth expected of a doctoral programme. The programme provides mobility, industrial experience and academic foundations in an integrated manner that will uniquely equip our future technology leaders to contribute to high-value innovation within EU industry.", "To": ["2022-03-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["Denmark"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2018-04-01"], "Project_ID": ["765636"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "UNIVERSITAET BASEL", "Isthmus", "UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6", "UNIVERSITY OF GLASGOW", "UNIVERSIDAD POMPEU FABRA", "BIOFACTION KG"], "EU_Contribution": ["EUR 2 968 817,50"], "Project_Title": ["Microbial deployment of new-to-nature chemistries for refactoring the barriers between living and non-living matter"], "Total_Cost": ["EUR 2 968 817,50"], "Country": ["Spain", "Switzerland", "Switzerland", "France", "France", "United Kingdom", "Spain", "Austria"], "Project_ACR": ["MADONNA"], "Technology_Description": "This Project is about bringing a suite of chemical reactions (and its related non-biological compounds and elements) to the biological fold (i.e. their 'biologization') by going beyond the Central Dogma of Molecular Biology (DNA\u2192 RNA\u2192 proteins\u2192 metabolism) through both tuning and overcoming the uni-directionality of the information flow. To reverse-engineer reactions into a biological code, the utility function of the chemical process of interest will be progressively coupled to the fitness function of a live carrier (e.g. an engineered, synthetic or cyborg-ized bacterial chassis), the intermediate steps being supported by automated chemo-robots. The new-to-nature reactions (NTN) pursued within the MADONNA lifetime as case studies will include CO2 capture and recruitment of elemental silicon to become part of essential organo-Si metabolites. Along with the development of the new reactions, the research agenda of the Project will also include the [i] modelling and prediction on the impact of the new biotransformations on the overall functioning of the Biosphere once/if adopted at a large scale by the industrial sector and [ii] design of environmental simulators for evaluating the performance and evolution of the new biological reactions under given physico-chemical settings. With such approaches, MADONNA aims to fill many of the gaps between the 3 types of global-scale processing of chemical elements operating in our planet: Geochemical, Biological and Industrial. The scale of applications of the foundational technologies developed herein (which spin themselves much beyond CO2 and silicon) is unprecedented and a large number of societal ramifications including ethical, security, safety, economic, governance and public perceptions aspects at stake will be included. If successful, MADONNA will enable an entirely new type of sustainable industry in which many types of waste become assets instead of liabilities.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-01-2016-2017 - FET-Open research and innovation actions"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-01-01"], "Project_ID": ["766975"], "Call_for_Proposal": ["H2020-FETOPEN-1-2016-2017"]}, -{"Partners": ["ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Visualizing the Conformational Dynamics of Proteins by Time-Resolved Electron Microscopy"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["ProteinDynamics"], "Technology_Description": "The function of many proteins involves large-amplitude domain motions that occur on a timescale of microseconds to millisecond. In the absence of tools to directly observe these dynamics, our understanding of the function of proteins is necessarily incomplete and must frequently rely on extrapolation from known static structures. Here, the implementation of real-time imaging of single particle dynamics in liquid phase is proposed with both microsecond time resolution as well as near-atomic spatial resolution. The experimental approach builds on several recent technological advances, namely the advent of Time-Resolved (\u201cFour-dimensional\u201d) Electron Microscopy, graphene liquid cell technology, and direct electron detection cameras, which are combined with established single-particle reconstruction techniques in cryo-Electron Microscopy. Visualizing the conformational dynamics of proteins will fundamentally advance our understanding of these nanoscale machines and has the potential to greatly benefit biomedical applications.", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["759145"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["TECHNISCHE UNIVERSITAET WIEN", "TECHNISCHE UNIVERSITAET WIEN", "FACULTY OF SCIENCE UNIVERSITY OF ZAGREB"], "EU_Contribution": ["EUR 2 133 950"], "Project_Title": ["The Janus-face of the localized carrier in cuprates: Generating the pseudogap and high temperature superconductivity"], "Total_Cost": ["EUR 2 133 950"], "Country": ["Austria", "Austria", "Croatia"], "Project_ACR": ["TheONE"], "Technology_Description": "The phenomenon of high-temperature (high-Tc) superconductivity (SC) is one of the most exciting, thoroughly investigated yet still unresolved problems in physics. A major difficulty in understanding high-Tc systems lies in the complexity of the materials and phase diagram. The delicate balance between material specific properties, disorder and the number of electronic phases superimpose makes it hard to identify the leading interactions. Consequently, theoretical models attempting to describe the high-Tc SC are significantly disparate and identifying the mechanism of SC at elevated temperatures is full of hardship.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["725521"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITAT DE BARCELONA", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "UNIVERSITEIT UTRECHT", "FLUIDIC ANALYTICS LIMITED", "SWEETCH ENERGY", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 3 299 670"], "Project_Title": ["TOWARDS NOVEL NANO-SCALE TECHNOLOGIES BASED ON PHORETIC FLOW EFFECTS"], "Total_Cost": ["EUR 3 299 670,01"], "Country": ["Spain", "United Kingdom", "Netherlands", "United Kingdom", "France", "France"], "Project_ACR": ["NANOPHLOW"], "Technology_Description": "Most devices that transport bulk fluids make use of pressure gradients (`pumps\u2019) or external forces (e.g. gravity powers hydro-electric turbines). Increasingly, modern technology is addressing problems where fluid transport takes place in sub-micron sized channels, or in pores. The physical laws of transport in such channels are qualitatively different from those that determine bulk flow; they are poorly understood and, importantly, barely exploited. The aim of the proposed research is to lay the basis for an entire novel technology where thermal gradients and concentration gradients along nano-sized channels are harnessed to drive devices that have no equivalent on the macroscopic scale. ", "To": ["2021-01-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-01-2016-2017 - FET-Open research and innovation actions"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations"], "From": ["2018-02-01"], "Project_ID": ["766972"], "Call_for_Proposal": ["H2020-FETOPEN-1-2016-2017"]}, -{"Partners": ["RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG", "RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG"], "EU_Contribution": ["EUR 1 220 325"], "Project_Title": ["Entangled Parliamentarisms: Constitutional Practices in Russia, Ukraine, China and Mongolia, 1905\u20132005"], "Total_Cost": ["EUR 1 220 325"], "Country": ["Germany", "Germany"], "Project_ACR": ["ENTPAR"], "Technology_Description": "The project addresses the entangled histories of deliberative decision making, political representation and constitutionalism on the territories of the former Russian and Qing Empires and focuses on the cases of Russia, Ukraine, China and Mongolia between 1905 and 2005. Employing the perspectives of the New Imperial History and Transcultural Studies, the project overcomes narrow state-centered approaches and takes advantage of multidisciplinary methodology crossing history and political science. The project traces parliamentary developments, the interactions among imperial and post-imperial intellectuals and their engagement in global discussions, shared imperial legacies, mutual borrowings and references, imperial and post-imperial political practices and translatability of concepts. It seeks to refute the stereotypes about inclinations towards democracy in particular national contexts by tracing relevant transnational practices and interactions and providing a nuanced political and intellectual history of parliamentarism. The team of five researchers (the PI, three PhD students and a post-doctoral researcher), will discuss and develop five individual and three cooperative studies. The PI will write a global history of parliaments and quasi-parliamentary institutions in Russia\u2019s imperial formations (the State Duma of the Russian Empire, the congresses of soviets and the Federal Assembly of the Russian Federation). The three PhD students with relevant language skills will focus on parliamentary developments in the Ukrainian, Chinese (including Hong Kong and Taiwan) and Mongolian contexts. The post-doctoral researcher will explore the translatability of concepts between Russian, Chinese, Mongolian, Ukrainian and English. The three cooperative projects will focus on traditional institutions of deliberative decision making in the abovementioned contexts; the Communist International and institutional exchange; and the role of parliaments in major social transformations.", "To": ["2023-03-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-04-01"], "Project_ID": ["755504"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 239 860,80"], "Project_Title": ["Morphology of Lithic Artifacts: Experimental and Morphometric Approaches"], "Total_Cost": ["EUR 239 860,80"], "Country": ["Germany"], "Project_ACR": ["MORPHOLITHEX"], "Technology_Description": "MORPHOLITHEX addresses one of the major research questions in prehistoric stone tool technologies - what are the crucial variables that knappers control to determine the form of their stone artifacts? Specifically, the project investigates the effects of variables that are under the direct control of the knapper, namely various platform management strategies and the morphology of the core surface, on the size and shape of the product. The project uses a novel combination of methods: the knapping process is simulated in an experimental setting that uses an apparatus that enables independent variables to be controlled and measured to isolate their effects on the final results; three-dimensional geometric morphometric methods are used to explore the size and shape of the blanks produced by the experiment; and advanced statistical modeling is used correlate the experimental predictors to the shape and size of the resulting blanks. The specific concentration is on platform management and core surface morphologies common in Levallois blank production, a technology that is present across the Old World during the last 300 thousand years, and is common during the rise and expansion of modern humans around 50 thousand years ago. The goal is to construct a more comprehensive model to account for morphological variation in stone tools and to validate this model using replicative and archeological collections. This quantitatively driven research integrates several of the most advanced approaches in our field and aims to significantly contribute to our understanding of the elementary principles of producing stone tools in prehistory. It further intends to make methodological advancements in controlled experiments for investigating the production of stone tools, as well as developing protocols for analyzing stone tool shape and size with geometric morphometrics.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-10-01"], "Project_ID": ["751125"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF DUNDEE"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Development of screw anchors for floating Marine Renewable Energy system arrays incorporating anchor sharing"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SAFS"], "Technology_Description": "Classical anchoring solutions are inappropriate for the development of new marine renewable energy devices (wind/waves/tides). They are too expensive and not efficient. Organising devices in arrays is a solution where adjacent devices share an anchor. It reduces the total number of anchors necessary and the overall cost. In turn the loading applied to an anchor is a complex combination of horizontal and uplift cyclic loads. Screw anchors are piles which are fitted with one or several helices at their end. They are installed into the soil by applying a torque and are assumed to have an excellent resistance against uplifting.", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["753156"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 278 227,80"], "Project_Title": ["Mind the Gut: Molecular Markers of Microbiome Evolution"], "Total_Cost": ["EUR 278 227,80"], "Country": ["Denmark"], "Project_ACR": ["MIND THE GUT"], "Technology_Description": "What is the role of our microbial partners in our evolution? Does the microbiome evolution reflect major events of human history? Despite increasing evidence that the gut microbiome plays an essential role in multiple core aspects of human biology, little is known about how the human-gut community co-evolved. The role of the microbiome in human evolution and speciation has been historically overlooked, in part due to the challenge of obtaining microbiome data from ancient material. However, understanding the co-evolution of the human-gut ecosystem requires a time-series approach associated with the major defining moments in human evolution such as migrations, admixture, domestication, industrialization and globalisation. Under favourable conditions some archaeological substrates such mummified tissues, coprolites and dental calculus have potential to shed some light on ancient microbiomes. ", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["750860"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FUNDACION BCMATERIALS - BASQUE CENTRE FOR MATERIALS, APPLICATIONS AND NANOSTRUCTURES", "FUNDACION BCMATERIALS - BASQUE CENTRE FOR MATERIALS, APPLICATIONS AND NANOSTRUCTURES"], "EU_Contribution": ["EUR 1 878 085"], "Project_Title": ["Molecularly Engineered Materials and process for Perovskite solar cell technology"], "Total_Cost": ["EUR 1 878 085"], "Country": ["Spain", "Spain"], "Project_ACR": ["MOLEMAT"], "Technology_Description": "Societal pressure to develop inexpensive yet efficient solar energy conversion requires a new approach. Recently emerged organic-inorganic perovskites, offer to harvest light at cost effective price. Perovskites hold merits to the existing materials, however, a fundamental challenge for high performance devices is to optimize the crystals for maximize charge carrier generation and minimize recombination losses. Their widespread use is, however, limited by insufficient stability, scalability and reproducibility. We have recently developed new concepts to fabricate efficient and stable perovskite solar cells at lab scale that are potentially up-scalable to industrial production. MOLEMAT will accomplish this by, pioneering innovative methods and will demonstrate that molecularly engineered materials enable the tuning of the charge transport and interface. Our interdisciplinary approach, combining materials science, chemistry, device physics and engineering, will not only lead to improvements in the performance and stability of perovskite solar cell beyond 24% at lab scale, but will also provide deep insights in the functioning of solar cells. The success of MOLEMAT will rapidly advance the field by enabling reproducible and stable performance adding a significant value with respect to current state of the art. However, for making it marketable product, several developments are required and the MOLEMAT targets will provide relevant answers to three key limitations: encapsulation, stability and cost competitive materials. MOLEMAT envisages the development of 30\u00d730 cm2 modules, with a power conversion efficiency of c.a 18% and a lifetime of 10+ years. MOLEMAT is divided into two parallel research directions, a fundamental research line, dealing with rational design of materials and to gain its understanding. Simultaneously an applied research line targets the development of module by the identification of scale up process to pave the way for its industrialization.", "To": ["2022-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-11-01"], "Project_ID": ["726360"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["PANEPISTIMIO KRITIS", "PANEPISTIMIO KRITIS"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Making it happen - Scalable biphasic reactions using a nebulizer-driven continuous flow reactor"], "Total_Cost": ["EUR 150 000"], "Country": ["Greece", "Greece"], "Project_ACR": ["NebuFlox"], "Technology_Description": "The original ERC grant focused on proving the power that oxygen from the air had in synthesis when its light-excited state was exploited. During the ERC program, we were able to show how simple & readily accessible start materials could be transformed into high value-high interest chemicals through straightforward \u201cone pot\u201d operations. We were also able to show that the diversity of structures accessible using this chemistry is remarkable. Furthermore, it is highly sustainable; representing a very efficient, benign & extremely low waste approach to the production of sought-after chemical frameworks. However, one problem prevailed. While it worked exceptionally well on a small research scale, its overall usefulness and its industrial relevance were severely curtailed by scale-up issues, even when the latest continuous flow technologies were applied. The need to achieve good light penetration, combined with the poor solubility of oxygen, seemed to castrate the potential of this chemistry to provide global solutions. A key breakthrough was made towards the end of the ERC program with the realization that creating and projecting a cloud (using a nebulizer to make fine droplets) into a light filled chamber could solve ALL the problems and lead to large scale reactions. With the current proposal, we seek to explore and fully automate this highly innovative nebulizer process in order to develop a robust prototype reactor with excellent prospects for further dimension enlarging (to industrial pilot plant scales & beyond). Furthermore, it is obvious that this \u201cnebulizer fix\u201d may also be superbly suited to other biphasic reactions. Our plan has the support of pharmaceutical giant AstraZeneca in the form of an automation expert who will act as mentor to the program. The PI & the advisory team will pursue a number of different commercialization opportunities delineated herein and look at how best to exploit and amplify the impact of the extremely efficient prototype reactor(s).", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Greece"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["779437"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE"], "EU_Contribution": ["EUR 1 473 175"], "Project_Title": ["Sublinear Algorithms for Modern Data Analysis"], "Total_Cost": ["EUR 1 473 175"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["SUBLINEAR"], "Technology_Description": "Designing efficient algorithms for fundamental computational tasks as well as understanding the limits of tractability has been the goal of computer science since its inception. Polynomial runtime has been the de facto notion of efficiency since the introduction of the notion of NP-completeness. As the sizes of modern datasets grow, however, many classical polynomial time (and sometimes even linear time) solutions become prohibitively expensive. This calls for sublinear algorithms, i.e. algorithms whose resource requirements are substantially smaller than the size of the input that they operate on. ", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["759471"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["KARLSRUHER INSTITUT FUER TECHNOLOGIE", "KARLSRUHER INSTITUT FUER TECHNOLOGIE"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["CellPrintArray \u2013 on-demand nano-scale printing of live cells and compounds for miniaturized cell screening applications"], "Total_Cost": ["EUR 150 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["CellPrintArray"], "Technology_Description": "The goal of this ERC-PoC project is to develop a prototype system that will enable the addition of libraries of drugs and biochemical molecules, reagents and cells from a 96 source plate directly to individual compartments of the target Droplet Microarray (DMA). The system should have controlled atmosphere (CO2, humidity, temperature) and should allow for dispensing controlled volumes (3-500 nL per experiment) and cell numbers (1-100 per experiment) into individual droplets. We aim to create and evaluate this system for applications commonly performed in pharmaceutical companies and screening centers to enable them to perform miniaturized and more predictive high throughput screenings using physiologically relevant cells such as primary cells, stem cells, biopsy-derived cells and other scarce cell types. The system should allow high-throughput screenings with patient derived cells and therefore will open new possibilities in drug discovery and personalized medicine.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["768929"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["CITY UNIVERSITY OF LONDON", "CHALMERS TEKNISKA HOEGSKOLA AB", "TECHNISCHE UNIVERSITEIT DELFT", "TECHNISCHE UNIVERSITAET MUENCHEN", "INSTITUT POLYTECHNIQUE DE GRENOBLE", "WAERTSILA NETHERLANDS B.V.", "Delphi Diesel Systems LTD", "AVL LIST GMBH"], "EU_Contribution": ["EUR 3 939 999,12"], "Project_Title": ["Development and experimental validation of computational models for cavitating flows, surface erosion damage and material loss"], "Total_Cost": ["EUR 3 939 999,12"], "Country": ["United Kingdom", "Sweden", "Netherlands", "Germany", "France", "Netherlands", "United Kingdom", "Austria"], "Project_ACR": ["CaFE"], "Technology_Description": "Cavitation, described as the formation of vapour/gas bubbles of a flowing liquid in a region where the pressure of the liquid falls below its vapour pressure, often leads to vibration and damage of mechanical components, for example, bearings, fuel injectors, valves, propellers and rudders, impellers, pumps and hydro turbines. Cavitation erosion when experienced, normally leads to significant additional repair and maintenance costs or component replacement. Even if erosion problems can be avoided by design or operation, most often the performance of the systems is sub-optimal because countermeasures by design are needed to prevent cavitation problems. Despite the long-lasting problems associated with cavitation, computational models that could simulate cavitation and identify locations of erosion are still not thoroughly developed. The proposed interdisciplinary training and research programme aims to provide new experimental data and an open-source simulation tool for hydrodynamic cavitation and induced erosion. Insight into the detailed bubble collapse mechanism leading to surface erosion will be realised through DNS simulations, which are now feasible by the significant progress in fluid flow computational methods and parallel simulations. Information from such models will be implemented as sub-grid scale models of URANS and LES approaches, typically employed for cavitation simulation at engineering scales. Model validation will be performed against new advanced X-ray, laser diagnostics and high speed imaging measurements to be performed as part of this project. Application of the developed models to cases of industrial interest includes fuel injectors, marine propellers, hydro-turbines, pumps and mechanical heart valves. From this understanding the development of methodologies for design of cavitation-free or remedial measures and operation of devices suffering from cavitation erosion can then be established for the benefit of the relevant communities.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["642536"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["ROYAL COLLEGE OF SURGEONS IN IRELAND", "UNIVERSITAET STUTTGART", "LUXEMBOURG INSTITUTE OF HEALTH", "VIB", "Institut du Cerveau et de la Moelle \u00e9pini\u00e8re", "ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM", "GENEXPLAIN GMBH", "INFORMATION TECHNOLOGY FOR TRANSLATIONAL MEDICINE (ITTM) SA", "AGILENT TECHNOLOGIES BELGIUM NV"], "EU_Contribution": ["EUR 3 836 772"], "Project_Title": ["Exploiting GLIOblastoma intractability to address European research TRAINing needs in translational brain tumour research, cancer systems medicine and integrative multi-omics"], "Total_Cost": ["EUR 3 836 772"], "Country": ["Ireland", "Germany", "Luxembourg", "Belgium", "France", "Netherlands", "Germany", "Luxembourg", "Belgium"], "Project_ACR": ["GLIOTRAIN"], "Technology_Description": "Glioblastoma (GBM) is the most frequent, aggressive and lethal of all brain tumours. It has a universally fatal prognosis with 85% of patients dying within two years. New treatment options and effective precision medicine therapies are urgently required. This can only be achieved by focused multi-sectoral industry-academia collaborations in newly emerging, innovative research disciplines. GLIOTRAIN will exploit the intractability of GBM to address European applied biomedical research training needs. The ETN, which comprises 9 beneficiaries and 14 partner organisations from 8 countries, will train 15 innovative, creative and entrepreneurial ESRs. The research objective of GLIOTRAIN is to identify novel therapeutic strategies for application in GBM, while implementing state of the art next generation sequencing, systems medicine and integrative multi-omics to unravel disease resistance mechanisms. Research activities incorporate applied systems medicine, integrative multi-omics leveraging state of the art platform technologies, and translational cancer biology implementing the latest clinically relevant models. The consortium brings together leading European and international academics, clinicians, private sector and not-for-profit partners across GBM fields of tumour biology, multi-omics, drug development, clinical research, bioinformatics, computational modelling and systems biology. Thus, GLIOTRAIN will address currently unmet translational research and clinical needs in the GBM field by interrogating innovative therapeutic strategies and improving the mechanistic understanding of disease resistance. The GLIOTRAIN ETN addresses current needs in academia and the private sector for researchers that have been trained in an environment that spans translational research, medicine and computational biology, and that can navigate confidently between clinical, academic and private sector environments to progress applied research findings towards improved patient outcomes.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-09-01"], "Project_ID": ["766069"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["ARISTOTELIO PANEPISTIMIO THESSALONIKIS", "ISTITUTO SUPERIORE DI SANITA", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "INSTITUT JOZEF STEFAN", "UNIVERSITE PARIS DESCARTES", "UNIVERSITAT ROVIRA I VIRGILI", "KENTRO TOXIKOLOGIAS ANONIMI ETAIRIA SYMVOULEYMKES DIAGNOSTIKES KAI ERGASTIRIAKES YPIRESIES TOXIKOLOGIAS FARMAKOLOGIAS KAI BIOIATRIKIS", "ZELENA INFRASTRUKTURA DRUSTVO S OGRANICENOM ODGOVORNOSCU ZA ZASTITU OKOLISA I PROSTORNO UREDENJE", "Istituto Universitario di Studi Superiori di Pavia", "ISTITUTO DI RICOVERO E CURA A CARATTERE SCIENTIFICO BURLO GAROFOLO"], "EU_Contribution": ["EUR 3 493 845"], "Project_Title": ["EXPLORING THE NEUROLOGICAL EXPOSOME"], "Total_Cost": ["EUR 3 493 845"], "Country": ["Greece", "Italy", "Spain", "Slovenia", "France", "Spain", "Greece", "Croatia", "Italy", "Italy"], "Project_ACR": ["NEUROSOME"], "Technology_Description": "The main objective of NEUROSOME is to develop an integrative biology-based framework starting from human biomonitoring data to unravel causal associations among the genetic predisposition, cumulative exposure to multiple environmental chemicals and neurological disorders. The project brings together beyond- the-state-of-the-art advances in human biomonitoring and systems biology, exposure monitoring and toxicological testing technologies and advanced tools for computational analyses of the exposure-to-health effect continuum following an exposome paradigm. The NEUROSOME methodology will be applied in population studies across different exposure settings to neurotoxicants (metals and persistent organics) in Europe. This will improve scientific knowledge on cause and-effect relations between environmental stressors and neurodevelopmental disorders taking into account exposure and health effect modification due to intrinsic (e.g. genetic susceptibility) and extrinsic (e.g. diet and socioeconomic status) factors. New standards for human biomonitoring data interpretation in conjunction with environmental and exposure information will be developed for ready use in chemical mixture risk assessment.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Greece"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2017-10-01"], "Project_ID": ["766251"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["UNIWERSYTET JAGIELLONSKI", "JOHANNES GUTENBERG-UNIVERSITAT MAINZ", "FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA", "UNIVERSITY OF YORK", "UNIVERSITAET ULM", "UNIVERSITY OF SOUTHAMPTON", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "UNIVERSITE LYON 1 CLAUDE BERNARD", "UNIVERSITA DEGLI STUDI DI TORINO"], "EU_Contribution": ["EUR 2 794 786,20"], "Project_Title": ["Zero and ultra-low field nuclear magnetic resonance"], "Total_Cost": ["EUR 2 794 786,20"], "Country": ["Poland", "Germany", "Italy", "United Kingdom", "Germany", "United Kingdom", "United Kingdom", "France", "Italy"], "Project_ACR": ["ZULF"], "Technology_Description": "Nuclear magnetic resonance (NMR) is a powerful technique employed in many areas of modern science and industry. While a seemingly indispensable element of NMR is a strong (>5 T) magnetic field, recent progress in physics and chemistry have enabled detection of NMR signals at ultra-low and truly zero magnetic fields. This completely reverses conditions under which spin-dynamics are investigated and gives access to information unavailable in conventional NMR. A secondary horizon is microscopic low-field magnetic sensors that probe NMR signals of a single molecule, and provide interesting information about molecular dynamics and structures not accessible with conventional NMR. The address of specific molecular sites is a step towards realizing single-molecule quantum information storage.", "To": ["2022-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Poland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Chiara Andreoli", "Tel.: +3901071781854", "Fax: +39 010 7170817", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["766402"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["UNIVERSIDAD AUTONOMA DE MADRID", "LANCASTER UNIVERSITY", "TECHNISCHE UNIVERSITEIT DELFT", "UNIVERSITY OF DURHAM", "IBM RESEARCH GMBH", "UNIVERSITAET BASEL", "EIDGENOSSISCHE MATERIALPRUFUNGS- UND FORSCHUNGSANSTALT"], "EU_Contribution": ["EUR 3 118 272,50"], "Project_Title": ["Quantum Interference Enhanced Thermoelectricity"], "Total_Cost": ["EUR 3 118 272,50"], "Country": ["Spain", "United Kingdom", "Netherlands", "United Kingdom", "Switzerland", "Switzerland", "Switzerland"], "Project_ACR": ["QuIET"], "Technology_Description": "Our vision is to demonstrate that room-temperature quantum interference effects, measured recently in single molecules, can be exploited in massively-parallel arrays of molecules and used to design ultra-thin-film thermoelectric devices with unprecedented ability to convert waste heat to electricity using the Seebeck effect and to cool at the nanoscale via the Peltier effect.", "To": ["2021-07-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-01-2016-2017 - FET-Open research and innovation actions"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["767187"], "Call_for_Proposal": ["H2020-FETOPEN-1-2016-2017"]}, -{"Partners": ["UNIVERSITY OF LEICESTER", "WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "RIJKSUNIVERSITEIT GRONINGEN", "BAYERISCHE JULIUS-MAXIMILIANS UNIVERSITAT WURZBURG", "Biologicke centrum AV CR, v. v. i.", "UNIVERSITY OF HAIFA", "UNIVERSITAT DE VALENCIA", "UNIVERSITA DEGLI STUDI DI PADOVA", "UNIWERSYTET JAGIELLONSKI", "THE HEBREW UNIVERSITY OF JERUSALEM"], "EU_Contribution": ["EUR 3 809 005,92"], "Project_Title": ["Comparative INsect CHRONobiology"], "Total_Cost": ["EUR 3 809 005,92"], "Country": ["United Kingdom", "Germany", "France", "Netherlands", "Germany", "Czech Republic", "Israel", "Spain", "Italy", "Poland", "Israel"], "Project_ACR": ["CINCHRON"], "Technology_Description": "Chronobiology is the study of biological rhythms. The best understood cycles are those with circadian 24 hour periods that modulate the temporal dynamics of physiology and behaviour of all higher organisms. Four model organisms have been widely used to study the underlying molecular biology of endogenous circadian clocks, Cyanobacteria, the fungus Neurospora, the fruitfly Drosophila, and the mouse. Insect clocks, both circadian and seasonal, are vital for adaptation to the environment and recent global patterns of climate change mean that insect pests and vectors of disease are expanding their ranges into Europe. Consequently there is an urgent need to study the circadian clocks of these insects and how they synchronise to the environment. CINCHRON will create an integrated European centre of excellence for the research training of ESRs in the emerging multidisciplinary field of Comparative INsect CHRONobiology. CINCHRON will bring together molecular neurogeneticists working predominantly with Drosophila, and comparative biologists who study circadian and seasonal clocks of non-model insects of economic importance. These researchers have different approaches so we will harness their different skills for mutual benefit via the integrated training of their ESRs in association with industrial partners. This will be done by high level interactions between university and industry, as well as interactions among laboratories with different areas of expertise, thereby connecting the different sectors (academic and commercial) as well as different disciplines. The goal is to seed-corn the next generation of researchers with highly trained, flexible workers in cutting edge technological methods and complementary generic skills that will support European academic, academic-related and industrial institutions. CINCHRON will therefore contribute to the integration and cohesion of future European research efforts in solving pure and applied biological problem.", "To": ["2022-05-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-06-01"], "Project_ID": ["765937"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "TECHNISCHE UNIVERSITEIT EINDHOVEN", "QUEEN MARY UNIVERSITY OF LONDON", "THE UNIVERSITY OF MANCHESTER", "UNIVERSITEIT GENT", "THE UNIVERSITY OF READING", "HUMBOLDT-UNIVERSITAET ZU BERLIN", "PSA AUTOMOBILES SA", "IONERA TECHNOLOGIES GMBH"], "EU_Contribution": ["EUR 3 926 899,80"], "Project_Title": ["Monomer sequence control in Polymers : Toward next-generation precision materials"], "Total_Cost": ["EUR 3 926 899,80"], "Country": ["France", "Netherlands", "United Kingdom", "United Kingdom", "Belgium", "United Kingdom", "Germany", "France", "Germany"], "Project_ACR": ["EURO-SEQUENCES"], "Technology_Description": "The aim of the project \u201cEuro-Sequences\u201d is to establish a multidisciplinary training network on the emerging topic of sequence-controlled polymers. It has been shown during the last 5 years that such polymers open up unprecedented options for the future of manmade materials. Indeed, similarly to biopolymers such as DNA and proteins, synthetic sequence-controlled polymers contain precisely engineered chain-microstructures that allow a fine control over their molecular, nanoscopic and macroscopic properties. For instance, these new types of polymers are relevant for applications in molecular data storage, catalysis, and nanomedicine. However, this field of research is young and therefore, fundamental and applied research is still mandatory. Thus, it seems timely and appropriate to federate top-European researchers working on that topic. The proposed network is composed of 7 academic partners and 2 companies and connects researchers with complementary expertise in areas such as organic chemistry, polymer synthesis, supramolecular chemistry, physico-chemistry and materials science. This multidisciplinary network will focus on different scientific aspects. A first important objective will be the development of facile and rapid chemical methods for \u2018writing\u2019 molecular information on polymers. In addition, analytical techniques that allow characterization and sequencing of polymers will be studied. The folding and self-assembly of sequence-controlled polymers will be also examined in order to understand the correlation between controlled primary structure and higher levels of organization. Eventually, a crucial aim of this project will be the conception of new types of plastics materials. This network will be a unique scientific environment for training PhDs. The students will conduct their research in top-European laboratories and will receive a complete training, including lectures and summer schools, on polymer chemistry, supramolecular chemistry and biomaterials.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["642083"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["EBERHARD KARLS UNIVERSITAET TUEBINGEN", "UNIVERSITA DEGLI STUDI DI MODENA E REGGIO EMILIA", "LUNDS UNIVERSITET", "HASKOLI ISLANDS", "SP PROCESS DEVELOPMENT AB", "INOCURE SRO", "OCULIS EHF", "PAMGENE INTERNATIONAL BV"], "EU_Contribution": ["EUR 3 327 702,84"], "Project_Title": ["Educating the next generation of scientists in translational medicine: Focus on eye diseases"], "Total_Cost": ["EUR 3 327 702,84"], "Country": ["Germany", "Italy", "Sweden", "Iceland", "Sweden", "Czech Republic", "Iceland", "Netherlands"], "Project_ACR": ["transMed"], "Technology_Description": "Medicine today experiences a gap between basic research and successful clinical translation that delays establishment of urgently needed therapies. This is very clearly so in blinding retinal degenerations (RDs), where most are yet untreatable, even with a wealth of basic and pre-clinical research data available. To address this problem, transMed proposes an innovative programme to educate \u201ctranslational researchers\u201d that focuses on the bench-to-bedside development of treatments for RD.", "To": ["2021-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-12-01"], "Project_ID": ["765441"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW", "PHILIPPS UNIVERSITAET MARBURG", "EBERHARD KARLS UNIVERSITAET TUEBINGEN", "BOTANICKY USTAV AV CR, V.V.I.", "INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE", "INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT", "ECSEQ GMBH", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "IGA TECHNOLOGY SERVICES SRL", "MARTIN-LUTHER-UNIVERSITAET HALLE-WITTENBERG", "GREGOR-MENDEL-INSTITUT F\u00dcR MOLEKULARE PFLANZENBIOLOGIE GMBH", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 3 784 150,80"], "Project_Title": ["Epigenetic Diversity in Ecology"], "Total_Cost": ["EUR 3 784 150,80"], "Country": ["Netherlands", "Germany", "Germany", "Czech Republic", "France", "France", "Germany", "Spain", "Italy", "Germany", "Austria", "Germany"], "Project_ACR": ["EPIDIVERSE"], "Technology_Description": "Plants are the foundation of all ecosystems and they provide humans with essential services. Unprecedented rates of global environmental change are now putting plants under increased risk, and it is important to understand the capacity of plants to adapt to rapid change. EPIDIVERSE takes a cross-disciplinary approach to investigate the role that epigenetic mechanisms, specifically DNA methylation, play in plant adaptation. Understanding the epigenetic contribution to adaptation will help to predict species responses to global warming and can open new directions for sustainable agriculture and crop breeding. In EPIDIVERSE, a consortium of academic and entrepreneurial PIs will train 15 ESRs to become a first generation of expert eco-epigeneticists, equipping them with the interdisciplinary skills - molecular, (epi)genomic, ecological and bioinformatics - to successfully tackle this new research area. Training in leading academic groups and in life sciences companies will emphasize empirical and informatics skills to become fluent and creative in extracting knowledge from big \u2018omics data in natural contexts. In so doing, EPIDIVERSE will ensure the ESRs, and Europe, leading positions in this emerging field. To explain the real-life relevance of epigenetics in natural systems, we will (1) develop genomic and bioinformatics tools for epigenomic analysis in natural settings; (2) determine natural epigenetic diversity, and its relationship with environmental factors, in three common wild species across Europe; and (3) reveal the molecular mechanisms underlying natural epigenetic diversity through controlled experiments. This approach is innovative and timely because it integrates several so far disconnected areas of epigenetic research, and it will transfer analytical methods from laboratory research to the real world. These are important steps forward if Europe wants to understand, manage, and possibly enhance plant adaptability to pressing environmental challenges.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Netherlands"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-09-01"], "Project_ID": ["764965"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["TECHNISCHE UNIVERSITAET BERLIN", "MATHCONSULT GMBH", "UNIVERSITAT LINZ", "MICROGATE SRL", "CONSORCIO INSTITUTO TECNOLOXICO MATEMATICA INDUSTRIAL ITMATI", "INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE", "UNIVERSITAET BREMEN", "BERGISCHE UNIVERSITAET WUPPERTAL", "STMICROELECTRONICS SRL", "FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG", "POLITECNICO DI MILANO", "SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI DI TRIESTE", "FORSCHUNGSVERBUND BERLIN EV"], "EU_Contribution": ["EUR 2 785 605,48"], "Project_Title": ["Reduced Order Modelling, Simulation and Optimization of Coupled systems"], "Total_Cost": ["EUR 2 785 605,48"], "Country": ["Germany", "Austria", "Austria", "Italy", "Spain", "France", "Germany", "Germany", "Italy", "Germany", "Italy", "Italy", "Germany"], "Project_ACR": ["ROMSOC"], "Technology_Description": "The development of high quality products and processes is essential for the future competitiveness of the European economy. In most key technology areas product development is increasingly based on simulation and optimization via mathematical models that allow to optimize design and functionality using free design parameters. Best performance of modelling, simulation and optimization (MSO) techniques is obtained by using a model hierarchy ranging from very fine to very coarse models obtained by model order reduction (MOR) techniques and to adapt the model and the methods to the user-defined requirements in accuracy and computational speed.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["765374"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["CONSIGLIO NAZIONALE DELLE RICERCHE", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSITY OF DURHAM", "KEMIJSKI INSTITUT", "LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN", "Masarykova univerzita", "POLITECNICO DI MILANO", "UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN", "ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA", "UNIVERSITAT WIEN", "ASTRAZENECA UK LIMITED", "BASECLICK GMBH", "DYNAMIC BIOSENSORS GMBH"], "EU_Contribution": ["EUR 3 827 591,28"], "Project_Title": ["DNA as a training platform for photodynamic processes in soft materials"], "Total_Cost": ["EUR 3 827 591,28"], "Country": ["Italy", "France", "United Kingdom", "Slovenia", "Germany", "Czech Republic", "Italy", "Ireland", "Italy", "Austria", "United Kingdom", "Germany", "Germany"], "Project_ACR": ["LightDyNAmics"], "Technology_Description": "Light interaction with biomaterials is the driving mechanism of fundamental biological processes, from photosynthesis to DNA photodamage, and is a powerful tool in biomedicine for analytical, diagnostic and therapeutic purposes. The main goal of LightDyNAmics is to achieve a complete understanding of the ultrafast dynamical processes at the molecular scale induced by UV light absorption in DNA, and to unveil the mechanisms leading to photodamage of the genetic code. At the same time, our project will transfer this knowledge on light-matter interaction to a broad class of optoelectronic materials, highly relevant for Europe`s high-tech industries.", "To": ["2022-03-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-04-01"], "Project_ID": ["765266"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["UNIVERSITAIR MEDISCH CENTRUM UTRECHT", "UNIVERSITAIR MEDISCH CENTRUM UTRECHT"], "EU_Contribution": ["EUR 1 997 297,99"], "Project_Title": ["Extracellular Vesicle-Inspired CArdiac Repair"], "Total_Cost": ["EUR 1 997 297,99"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["EVICARE"], "Technology_Description": "More than 3.5 million people are newly diagnosed with heart failure every year in Europe with a long-term prognosis of 50% mortality within 4 years. There is a major need for more innovative, regenerative therapies that have the potential to change the course of disease. My hypothesis is that we can recondition heart failure by stimulating cardiac repair with extracellular vesicles that are derived from progenitor cells. In my laboratory, extracellular released vesicles containing a cocktail of stimulating factors, are amongst the most potent vectors for cardiac repair.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["725229"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITEIT MAASTRICHT", "FONDAZIONE IRCCS ISTITUTO NAZIONALE DEI TUMORI", "UNIVERSITE DE LIEGE", "ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM", "DEUTSCHES KREBSFORSCHUNGSZENTRUM", "INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE", "ONCORADIOMICS", "MIRADA MEDICAL LTD", "PERSPECTUM DIAGNOSTICS LTD", "HEALTH INNOVATION VENTURES BV"], "EU_Contribution": ["EUR 3 860 059,68"], "Project_Title": ["A new era in personalised medicine: Radiomics as decision support tool for diagnostics and theragnostics in oncology"], "Total_Cost": ["EUR 3 860 059,68"], "Country": ["Netherlands", "Italy", "Belgium", "Netherlands", "Germany", "France", "Belgium", "United Kingdom", "United Kingdom", "Netherlands"], "Project_ACR": ["PREDICT"], "Technology_Description": "The high degree of tumour (genomic and phenotypic) heterogeneity influences patient\u2019s response to therapy and hampers wide deployment of personalised medicine for cancer treatment. Thus, there is an imperative need for new technologies that can accurately detect tumour heterogeneity, allow for patient stratification and assist clinicians in providing the right diagnosis and treatment for the right patient. PREDICT\u2019s mission is to address this huge unmet need.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-10-01"], "Project_ID": ["766276"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["UNIVERSITY OF HULL"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["A Novel Hybrid Photovoltaic\u2013Thermoelectric Power Generation System Employing the Flat-plate Micro-channel Heat Pipe"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["PV-TE-MCHP"], "Technology_Description": "Integrating a thermoelectric (TE) module into a PV module can convert the accumulated heat of the PV into electricity, thus increasing electricity yield of the unit. A traditional spectrum integration PV-TE unit, by coupling the equal sized TE and PV modules, can harvest 30% more electricity than the PV unit alone. However, the pair-arrangement between the PV and TE modules appears to be economically unfeasible, owing to the significantly higher cost and lower power output of the TE module. By introducing a low cost and high efficiency micro-channel heat pipe (MCHP) and placing the PV onto the evaporator of the MCHP and TE underneath its condenser, the system\u2019s cost will be significantly reduced while its power output remains almost same as to the pair-arranged PV-TE system. The proposed MSCA programme aims to characterise and optimise the novel PV-TE-MCHP, by integrating the excellence of the host applicant in PV and MCHP and the expertise of the researcher applicant in TE, solar energy and heat transfer technology, and by sharing the knowledge of both the host and researcher applicants in PV/T and computer simulation. The tasks involved include (a) conceptual design; (b) computer modelling/optimisation; (c) prototype construction & testing; and (d) economic and environmental performance analyses. As a result, the programme will deliver a novel PV-TE-MCHP prototype that, compared to the existing PV-TE systems, has a significantly lower cost while the electrical output remains the same. From the MSCA point of view, the project will attract an experienced researcher with particular knowledge in PV/T, TE and computer simulation into Europe. This will (a) achieve transfer of knowledge from outside into Europe, thus helping growing EU\u2019s knowledge-based economy and society; (b) develop a long term contact network among the researcher, host organisation, partner organisation and other associated institutions; and (c) enable advanced training to the researcher.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["745614"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSIDADE DE EVORA", "UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA", "BEN-GURION UNIVERSITY OF THE NEGEV", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "POLITECNICO DI TORINO", "UNIVERSITE D'AVIGNON ET DES PAYS DE VAUCLUSE", "UNIVERSIDAD DE BURGOS", "UNIVERSITE BORDEAUX MONTAIGNE", "INSTITUTE OF COMMUNICATION AND COMPUTER SYSTEMS"], "EU_Contribution": ["EUR 3 298 257,36"], "Project_Title": ["European Doctorate in ARchaeological and Cultural Heritage MATerials science"], "Total_Cost": ["EUR 3 298 257,36"], "Country": ["Portugal", "Italy", "Israel", "Spain", "Italy", "France", "Spain", "France", "Greece"], "Project_ACR": ["ED-ARCHMAT"], "Technology_Description": "The ED-ARCHMAT (European Doctorate in Archaeological and Cultural Heritage Materials Science) EJD aims to train a new generation of creative and entrepreneurial ESR able to face current and future challenges in Archaeological/Cultural Heritage protection and management and to convert knowledge and ideas into products and services for economic and social benefit. The study, management and optimization of Archaeological and CH sites and objects is a sector with a strong multidisciplinary connotation. Accordingly the ED-ARCHMAT international consortium includes HEI, SME, Museums, Conservations Labs (such as the GCI in LA), and IT/Business Schools and proposes a coherent joint doctoral program aiming at overcoming national, sectoral and inter-disciplinary boundaries in PhD research in the field of Archaeometry/Conservation Science. The ED-ARCHMAT EJD will have a strong ESR mobility component, with the final goal of leading to lasting PhD-level cooperation between beneficiaries and partners. The EJD will also strengthen the transmission and exploitation of knowledge and enhance the innovation process in the general CH area where the increasing development of more sophisticated chemical and physical analytical techniques and of ICT have highlighted the existence of a knowledge gap that needs to be filled. The successful ED-ARCHMAT ESR will acquire innovative skills and key competence spanning across the Humanities, Materials Science, Business and Management fields, acquiring the professional figure of Conservation Scientist 1) Conservation science ; 2) Development of Diagnostic and Monitoring tools; 3) New Conservation Materials and Methods: characterization of artifacts degradation mechanisms, performance evaluation of new materials, decision making techniques, 4) Equipments : skills in the utilization of different instrumentations, 5) Energy efficient and sustainable solutions for CH materials; 6) Management and entrepreneurship in Cultural Heritage", "To": ["2022-03-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EJD - European Joint Doctorates"], "Coordinated_in": ["Portugal"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2018-04-01"], "Project_ID": ["766311"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["CARDIFF UNIVERSITY"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Mathematical models of bone externally excited remodelling"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["MMoBEER"], "Technology_Description": "For describing complex systems as bone tissue, with their inner interactions and their interactions with environment the mathematical models become even more complex, that puts demands on theories, methods and assumptions used and the efficiency of numerical methods employed for solving as well as the management of data. The complexity of bone models depends not only on the number of parameters describing different biochemistry and Multi-physics influences but also on different time scales and rate of periodicity of processes involved. In structural analysis non-linearity plays important role for realistic description of real world phenomena. Incorporated the parametric nonlinear analysis of periodically excited hybrid systems into a structural models of bone would be a great advantages for prediction of a more realistic situation for description of the bone mass distribution, delay in the osteoblasts and osteoclasts coupling, osteocytes transferring of signals and more other issues related to the bone adaptively and strength. The aim of the project would be that on the base of existing level of known parameters in bone turnover guided by external loading provide an analytical approach to be solve and interpreted for real description and prediction of bone adaptive behavior. Hybrid systems treat cellular level as discrete system of particles described with system of coupled ordinary differential equations and environmental conditions as a continuous system described with a system of coupled partial differential equations affected with different external signals. The established, measured and explored model will also give an approach closer to the realistic situation and real needs and suggestions for patients with bone problems but also for those who want to have healthy and strong skeleton.", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["752793"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["EUROPEAN MOLECULAR BIOLOGY LABORATORY", "EUROPEAN MOLECULAR BIOLOGY LABORATORY"], "EU_Contribution": ["EUR 2 239 458"], "Project_Title": ["Self-organisation across the scales in early mammalian development"], "Total_Cost": ["EUR 2 239 458"], "Country": ["Germany", "Germany"], "Project_ACR": ["SelforganisingEmbryo"], "Technology_Description": "A defining feature of multi-cellular living systems is the capacity to break symmetry and generate patterns through self-organisation. Our project aims to understand the design principle of multi-cellular self-organisation, using a well-suited model system: early mouse embryos. In mammals eggs lack polarity and symmetry is broken during early embryogenesis, which results in segregation of three cell lineages in the blastocyst. Progressive expansion and coalescence of fluid-filled spaces form the blastocyst cavity that segregates the cavity-facing lineage from the rest. Despite extensive gene expression studies, how molecular and physical signals are dynamically coupled for self-organised blastocyst patterning remains poorly understood. We aim to identify the mechanisms of feedback between cell polarity, mechanics (contractility, adhesion, pressure) and fate operating across sub-cellular to whole organismal scales. For this, we adopt a unique set of strategies that integrate biology and physics: advanced live-imaging, quantification of molecular and physical parameters to integrate into lineage maps, reduced systems to establish physical models, and spatio-temporally controlled manipulations for functional validation of those models. We will build up complexities. At the single-cell level, we will study de novo assembly of the apical domain in relation to cell contact and cortical contractility. For inside-outside patterning, we aim to dissect the coordinated signalling between cell position and fate specification. Furthermore, we will study how fluid cavities, a yet unexplored parameter, contribute to cell sorting, apical polarisation and fate specification through generation of pressure and contact-free cell surfaces. Ultimately, we will reconstitute embryogenesis in silico, reveal emerging properties and design engineer the blastocyst. In all, this study will set a paradigm for studying self-organisation on subcellular to organismal scales.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-09-01"], "Project_ID": ["742732"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 493 838,77"], "Project_Title": ["Fundamental Understanding of Nanoparticle chemistry: towards the prediction of Particulate emissions and Material synthesis"], "Total_Cost": ["EUR 1 493 838,77"], "Country": ["France", "France"], "Project_ACR": ["FUN-PM"], "Technology_Description": "While modern societies are facing urgent challenges related to reduction of particulate matter emissions from transportation engines, recent discoveries on the extraordinary properties of carbonaceous functional nanomaterials have revealed opportunities associated with large-scale, flame-based synthesis of these otherwise unwanted combustion products. In both cases, our ability to study new, optimized solutions based on the specific industrial end-user needs is limited by the absence of theoretical tools able to accurately predict the fluid dynamics and the chemistry involved in nanoparticle formation. Indeed, current knowledge on this fascinating but complex process is still rather incomplete. The proposed research program, FUN-PM, will apply an innovative multi-disciplinary, multi-step approach in order to finally answer many unresolved kinetic questions concerning in particular: 1) formation and growth of molecular PAH precursors; 2) particle inception; 3) subsequent particle growth and oxidation. Each single step will be experimentally isolated taking full advantage of complementary conventional shock tube techniques and up-to-date synchrotron-based detection technologies coupled to a newly constructed high-rate repetition shock tube. If successful, the novel synchrotron-shock tube techniques will be utilized for the first time to obtain unique information on unknown key processes. The experimental results, with extensive theoretical ab-initio calculations on relevant PAH reaction pathways, will constitute the base for the development of a comprehensive, detailed chemical kinetic model for particle chemistry applied to Real Fuels. Such model will improve the prediction capabilities of current CFD codes for use in engine design, fuel reformulation, or industrial process optimization, with considerable benefits to the standards of living of European citizens, the environment, and the EU economy, towards the future of clean transportations and novel nanomaterials.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-02-01"], "Project_ID": ["756785"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET", "KOBENHAVNS UNIVERSITET", "UNIVERSITY COLLEGE LONDON", "DANMARKS TEKNISKE UNIVERSITET"], "EU_Contribution": ["EUR 2 500 000"], "Project_Title": ["Generalised Entropy Models for Spatial Choices"], "Total_Cost": ["EUR 2 574 486,25"], "Country": ["Denmark", "Denmark", "United Kingdom", "Denmark"], "Project_ACR": ["GEM"], "Technology_Description": "This project will create a new category of models that can be used for describing a wide range of spatial choice problems in the social sciences. Spatial settings often have a very large number of choice alternatives. Discrete choice models are used extensively to make counterfactual predictions based on observations of individual choices. Despite forty years of research, current spatial choice models still have two major generic short-comings that seriously limit their ability to make counterfactual predictions. The new category of models will address these two short-comings.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["740369"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6"], "EU_Contribution": ["EUR 166 603,20"], "Project_Title": ["Geometry of Nonnegative Rank"], "Total_Cost": ["EUR 166 603,20"], "Country": ["France"], "Project_ACR": ["NonnegativeRank"], "Technology_Description": "This proposal is centered on nonnegative rank - a notion that modifies the definition of matrix rank. This project is basic research aimed to better understand the geometry of matrices and tensors of nonnegative rank at most r, how this knowledge can be employed to improve exact and numerical nonnegative matrix algorithms, obtain an algorithm for nested polytopes in dimension three, and address questions about mixture models in statistics. Computing and understanding nonnegative rank is truly interdisciplinary. Completing this project requires techniques from polyhedral geometry, real algebraic geometry, optimization, statistics, symbolic algebra, and numerics.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["748354"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF BRIGHTON"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Dual Function Polymer Materials for Blood Contacting Applications"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["DualFun"], "Technology_Description": "Surface-induced thrombosis and infection are two main complications which cause failure of medical devices. Device-related thrombosis is associated with activation of blood clotting and platelets adhesion and activation. Infection of the implanted devices occurred as a result of bacteria adhesion to the biomaterial surface. A genuinely biocompatible polymer for blood-contacting devices should have both antithrombotic and antibacterial functionalities as both types of complication lead to an increase in morbidity, extended hospital stay and mortality.", "To": ["2019-09-17, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-18"], "Project_ID": ["749207"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAET BERN", "UNIVERSITAET BERN"], "EU_Contribution": ["EUR 2 499 380"], "Project_Title": ["Reconstruction of Pollinator-Mediated Speciation by Identification and Substitution of Causative Mutations"], "Total_Cost": ["EUR 2 499 380"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["RESPEC"], "Technology_Description": "A central aim of contemporary research on the origin of species is to identify the genes that are functionally differentiated between nascent species. Understanding the molecular-genetic basis of speciation will answer important questions that are of broad interest to geneticists, ecologists and evolutionary biologists. The RESPEC project will identify such \u201cspeciation genes\u201d, map them onto conventional phylogenies and genetically reconstruct the process of speciation. Pollinator-mediated speciation is an attractive system to achieve these goals. Speciation in Petunia is recent, ongoing and prezygotic. Shifts in pollination syndromes are complex but are composed of distinct traits that can be studied individually. The advertising traits color and scent are known to be encoded by major effect genes, but for morphological traits no such information is available.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["741354"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITAET BERN"], "EU_Contribution": ["EUR 187 419,60"], "Project_Title": ["Maternal Enteric Microbiota for Offspring's Repertoire development and Illness Susceptibility"], "Total_Cost": ["EUR 187 419,60"], "Country": ["Switzerland"], "Project_ACR": ["MEMORIS"], "Technology_Description": "Recently, it has emerged that early life exposure to commensal microbes is crucial to instruct our immune system and prevent later life autoimmune and metabolic diseases. The host lab now showed that this education begins even earlier \u2013 during gestation by signals from the maternal intestinal microbiota. Using the E. coli strain HA 107, genetically engineered to grow in vitro without the ability to persist in vivo, they demonstrated that transient intestinal colonisation of pregnant germ-free mouse dams drives neonatal innate immune maturation. However, the long-term consequences of maternal microbiota cues especially for the adaptive immune system of the adult offspring remain elusive.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["744257"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 497 547"], "Project_Title": ["Structural and Functional Architectures of Multi-Kingdom Microbial Consortia Colonizing Plant Roots"], "Total_Cost": ["EUR 1 497 547"], "Country": ["Germany", "Germany"], "Project_ACR": ["MICRORULES"], "Technology_Description": "The roots of healthy plants are colonized by a rich diversity of microbes, forming multi-kingdom microbial consortia that impact plant productivity. Despite the expected high connectivity between root microbiota members, our understanding of microbe-microbe interactions in structuring microbial networks in plant roots as well as their functional impact on plant growth remains poorly understood. Based on recent findings in my group, I propose a conceptual framework aiming at a functional understanding the holo-plant microbiome, where microbial interactions play an integral role in structuring root-associated microbial communities and maintaining microbiota balance and plant health. ", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-09-01"], "Project_ID": ["758003"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["KEYGENE NV"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["Aeroponic Inulin and Rubber"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["AIR"], "Technology_Description": "Natural rubber is an essential commodity for the European society. However, the natural rubber market is seriously endangered. Finding an alternative rubber source for the rubber tree is an urgent issue for EU. The EU has funded several projects on alternative rubber crops in the past. Taraxacum koksaghyz (TKS) was identified as the most promising alternative. However, this wild plant is small and does not produce sufficient rubber to be economically profitable. Rubber production can be increased by plant breeding and by improving the growing conditions.", "To": ["2020-02-29, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-SE - Society and Enterprise panel"], "Coordinated_in": ["Netherlands"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-03-01"], "Project_ID": ["752921"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["PRINS LEOPOLD INSTITUUT VOOR TROPISCHE GENEESKUNDE", "PRINS LEOPOLD INSTITUUT VOOR TROPISCHE GENEESKUNDE", "MEDICAL RESEARCH COUNCIL", "UNIVERSITE CATHOLIQUE DE LOUVAIN", "DALBERG DATA INSIGHTS"], "EU_Contribution": ["EUR 149 783"], "Project_Title": ["Enhanced Place Finding (EPF) of TB transmission hotspots"], "Total_Cost": ["EUR 149 783"], "Country": ["Belgium", "Belgium", "United Kingdom", "Belgium", "Belgium"], "Project_ACR": ["TB-EPF"], "Technology_Description": "TB is transmitted via person-to-person aerosols. Recent studies suggests that in TB endemic areas up to 70% of transmission events take place outside the household in public places. Moreover, TB transmission is unequally spatially distributed and occurs in transmission hotspot areas. Mathematical models consequently demonstrated that identifying hotspots and blocking within-hotspot-transmission through targeted public health interventions will be the most efficient way of lowering the TB burden. In the present PoC proposal we aim to complement the population-based Enhanced-Case-Finding intervention tested in the INTERRUPTB study, with a spatially more targeted \u201cEnhanced-Place-Finding\u201d (EPF) approach to identify transmission hotspots in an unbiased fashion. Using traditional methods to find transmission hotspots can only be done retrospectively after years of data collection. Therefore we propose a novel EPF strategy to detect transmission hotspots in real-time using phone-tracking technology to establish a spatial map of aggregated TB patients movements. Within the ERC-funded INTERRUPTB study in The Gambia, we sequenced 2000 mycobacterial isolates, which allows us to establish a bacterial genetic transmission network. Within the PoC proposal, we seek to reconsent these patients to analyze their everyday movements using classical contact investigation complemented by phone tracking, to determine which public places have an increased risk of TB transmission. We aim to demonstrate that phone tracking of TB patients can be a cheap, easy, and, most importantly, prospective TB transmission hotspots identification tool, no longer requiring molecular epidemiological investigations. Such a finding can ultimately be developed into an app that warns national TB programs of early TB outbreaks, so that early public health measures like increased ventilation and active case finding can be initiated. This approach can furthermore be applied to other infectious diseases.", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-09-01"], "Project_ID": ["727695"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["DOW CORNING EUROPE SA", "UNIVERSITA DEGLI STUDI DI FERRARA", "UNIVERSITE DE FRIBOURG"], "EU_Contribution": ["EUR 773 848,08"], "Project_Title": ["Impact of air pollutants on cutaneous responses in both healthy and compromised skin barrier, and innovative solutions to protect skin against urban pollution"], "Total_Cost": ["EUR 773 848,08"], "Country": ["Belgium", "Italy", "Switzerland"], "Project_ACR": ["CITYCARE"], "Technology_Description": "Nowadays, our skin is increasingly more assaulted, as a result of the increasingly complexity of our living environment. Because of its critical location, the skin is continuously exposed not only to natural environmental stress factors, such as UV radiation, ozone and extreme weather conditions associated with climatic changes, but also to pollutants/aggressors of anthropic origin, such as cigarette smoke and diesel/gasoline fuel exhaust. By combining the complementary expertise of the three partners involved in the present consortium, i.e. polymer technology and formulation expertise (DCE), skin barrier understanding and biochemistry/molecular biology (UoF), and impact of diesel/gasoline exhaust on cellular responses (UNIFR), this project will aim (i) at better understanding the consequences of air pollutants on both skin integrity and function, (ii) at investigating the synergistic effects of air pollutants such as ozone, cigarette smoke and diesel exhaust with UV radiation, (iii) at discovering innovative solutions to protect skin against those environmental stressors using both a curative approach based on the optimization of the delivery and efficacy of antioxidant compounds, and a preventive approach, based on the formation of a polymeric barrier film at the skin surface, (iv) at studying the impact of air pollutants on both healthy skin and compromised, damaged skin since the number of individuals suffering from skin diseases such as atopic dermatitis and psoriasis continuously increases with the increasingly level of air pollution and air-conditioning systems. The variety of training offered under this EID proposal will enable three early-stage researchers to build strong S&T background as well as to develop numerous transferable skills for their future career. The present training program will allow the researchers to expand their knowledge to new domains and applications, while also providing good networking opportunities.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["Belgium"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["765602"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["FONDAZIONE TELETHON", "THE UNIVERSITY OF EDINBURGH", "UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II.", "UNIVERSITE PARIS DIDEROT - PARIS 7", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE", "UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 2 975 345"], "Project_Title": ["Control Engineering of Biological Systems for Reliable Synthetic Biology Applications"], "Total_Cost": ["EUR 2 996 856,25"], "Country": ["Italy", "United Kingdom", "Italy", "France", "Switzerland", "United Kingdom", "France", "United Kingdom"], "Project_ACR": ["COSY-BIO"], "Technology_Description": "Synthetic Biology aims at rational engineering of living organisms to improve human well-being and environmental sustainability, thus promising a paradigm shift in human technology. Its full potential has not been achieved yet because of the complexity of engineering biological systems where basic biological parts are intrinsically noisy and not modular. The overarching goal of COSY-BIO is to develop a theoretical framework and innovative technological tools to engineer reliable biological systems that are robust despite their individual components being not by translating principles of control engineering to molecular and cell biology. Automatic control is a well-established engineering discipline to build \u201ccontrollers\u201d to steer the dynamic behaviour of a physical system in a desired fashion. By building upon control engineering for physical systems and by exploiting the unique features of living organisms, this project will identify generally applicable approaches to design closed-loop feedback controllers for biological systems. To handle biological complexity, the project will explore three strategies of increasing difficulty \u201cexternal\u201d controllers, \u201cembedded\u201d controllers and \u201cmulti-cellular\u201d controllers. External controllers will be implemented in a computer acting on cells using small molecules via microfluidics devices. Embedded controllers will be made from biological parts and integrated within individual cells to steer their behaviour. Multicellular controllers envisage two cell populations, one made up of cells with embedded controllers (controller cells) and the other will be the controlled population (target cells). In addition, a rapid prototyping platform will enable to speed up the design-build-test cycles by means of optimal experimental design, microfluidics and cell-free systems. Proof-of-principles demonstrations in bacteria and yeast with relevance to biotechnology will be tackled to prove the usefulness of this revolutionary technology.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-01-2016-2017 - FET-Open research and innovation actions"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["766840"], "Call_for_Proposal": ["H2020-FETOPEN-1-2016-2017"]}, -{"Partners": ["UNIVERSITY OF BRADFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "TECHNISCHE UNIVERSITEIT DELFT", "UNIVERSIDAD DE ZARAGOZA", "JUSTUS-LIEBIG-UNIVERSITAET GIESSEN", "BILKENT UNIVERSITESI VAKIF", "UNIVERSITAET ULM", "UNIVERSITY OF SOUTHAMPTON", "UNIVERSITY OF NEWCASTLE UPON TYNE"], "EU_Contribution": ["EUR 2 834 979,84"], "Project_Title": ["DyViTo: Dynamics in Vision and Touch - the look and feel of stuff"], "Total_Cost": ["EUR 2 834 979,84"], "Country": ["United Kingdom", "United Kingdom", "Netherlands", "Spain", "Germany", "Turkey", "Germany", "United Kingdom", "United Kingdom"], "Project_ACR": ["DyViTo"], "Technology_Description": "Real world tasks as diverse as drinking tea or operating machines require us to integrate information across time and the senses rapidly and flexibly. Understanding how the human brain performs dynamic, multisensory integration is a key challenge with important applications in creating digital and virtual environments. Communication, entertainment and commerce are increasingly reliant on ever more realistic and inmmersive virtual worlds that we can modify and manipulate. Here we bring together multiple perspectives (psychology, computer science, physics, cognitive science and neuroscience) to address the central challenge of the perception of material and appearance in dynamic environments. Our goal is to produce a step change in the industrial challenge of creating virtual objects that look, feel, move and change like \u2018the real thing\u2019. We will accomplish this through an integrated training programme that will produce a cohort of young researchers who are able to fluidly translate between the fundamental neuro-cognitive mechanisms of object and material perception and diverse applications in virtual reality. The training environment will provide 11 ESRs with cutting-edge, multidisciplinary projects, under the supervision of experts in visual and haptic perception, neuroimaging, modelling, material rendering and lighting design. This will provide perceptually-driven advances in graphical rendering and lighting technology for dynamic interaction with complex materials (WP1-3). Central to the fulfillment of the network is the involvement of secondments to industrial and public outreach partners. Thus, we aim to produce a new generation of researchers who advance our understanding of the \u2018look and feel\u2019 of real and virtual objects in a seamlessly multidisciplinary way. Their experience of translating back and forth between sectors and countries will provide Europe with key innovators in the developing field of visual-haptic technologies.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["765121"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["UNIVERZITET U NOVOM SADU FAKULTET TEHNICKIH NAUKA", "University of Novi Sad Faculty of Sciences", "Kreativno edukativni centar", "VISOKA TEHNICKA SKOLA STRUKOVNIH STUDIJA U ZRENJANINU", "Udruzenje naucnih komunikatora", "CENTAR ZA PROMOCIJU NAUKE"], "EU_Contribution": ["EUR 98 000"], "Project_Title": ["Friend to understand"], "Total_Cost": ["EUR 112 700"], "Country": ["Serbia", "Serbia", "Serbia", "Serbia", "Serbia", "Serbia"], "Project_ACR": ["Friend2U"], "Technology_Description": "Our mission of exposing the researchers as ordinary people with an extraordinary job to the public at large in Serbia started in 2010. Annual impact assessment reports show that we significantly influenced the perception and knowledge of the general public regarding WHAT the researchers do, but they also showed that there is room for improving the ways of showing WHO the researchers are, by making the personalities and faces of the researchers recognizable to the society, as well as in clarifying WHY they become researchers, i.e. their motivation and inspiration to explain why research matters to society. Therefore, without losing a focus on WHAT, RN 2014-2015 will focus on the questions of WHO and WHY in order to offer a new dimension of perceiving the researchers and offer more answers beyond the WHAT question. ", "To": ["2015-12-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-NIGHT-2014 - European Researchers' Night (NIGHT)"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Serbia"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2014-05-01"], "Project_ID": ["633396"], "Call_for_Proposal": ["H2020-MSCA-NIGHT-2014"]}, -{"Partners": ["UNIVERSIDAD AUTONOMA DE MADRID", "UNIVERSIDAD AUTONOMA DE MADRID"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Imaging-XChem: A computational package for ultrafast electronic control in chemistry"], "Total_Cost": ["EUR 150 000"], "Country": ["Spain", "Spain"], "Project_ACR": ["Imaging-XChem"], "Technology_Description": "Commercial quantum-chemistry computational packages are widely used in science and chemical industry to predict the properties and reactivity of molecules and to design new compounds and drugs that can eventually be synthesized in the laboratory. The software developed in the framework of the ERC AdG project XCHEM is aimed at providing a full quantum mechanical description of a large variety of chemical processes that cannot be addressed by standard quantum chemistry packages, namely those processes in which molecular ionization takes place. An accurate description of molecular ionization is crucial to develop new applications and make reliable predictions in emerging scientific disciplines, such as attochemistry, single-molecule imaging, and coherent attosecond control of chemical reactions. ", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["780284"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["WAGENINGEN UNIVERSITY", "UNIVERSITAET BREMEN", "RIJKSUNIVERSITEIT GRONINGEN", "INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE", "INSTITUTO VALENCIANO DE INVESTIGACIONES AGRARIAS", "Biologicke centrum AV CR, v. v. i.", "KOPPERT BV", "FOOD AND AGRICULTURE ORGANIZATION OF THE UNITED NATIONS FAO", "CAB INTERNATIONAL", "VETERINAERMEDIZINISCHE UNIVERSITAET WIEN"], "EU_Contribution": ["EUR 3 288 069"], "Project_Title": ["Breeding Invertebrates for Next Generation BioControl (BINGO)"], "Total_Cost": ["EUR 3 288 069"], "Country": ["Netherlands", "Germany", "Netherlands", "France", "Spain", "Czech Republic", "Netherlands", "Italy", "United Kingdom", "Austria"], "Project_ACR": ["BINGO"], "Technology_Description": "BACKGROUND", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2015-01-01"], "Project_ID": ["641456"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["UNIVERSITAETSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITAET MAINZ", "UNIVERSITAETSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITAET MAINZ"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Bifunctional and regeneratively active biomaterial: Towards an ultimate solution for osteoarthritis treatment"], "Total_Cost": ["EUR 150 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["ArthroDUR"], "Technology_Description": "Osteoarthritis (OA) is the most common form of arthritis of the joints, affecting over 70 million EU citizens. At present, no cure for OA is available; only symptomatic therapies may help to ameliorate this painful disorder. OA affects the integrity of the cartilage and progresses to an increased damage in its surrounding tissues, inclusive bone, and to inflammation of the synovial tissue. The latter reaction is caused by an accumulation of bone splinters. The therapy of choice would be \u2013 if available \u2013 bidirectional: first, regeneration of the damaged cartilage (by implants) and second, dissolution of the bone fragments (by injections). This proposal presents for the first time this two-fold solution. ", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["767234"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 484 688"], "Project_Title": ["Comet and Asteroid Re-Shaping through Activity"], "Total_Cost": ["EUR 1 484 688"], "Country": ["Germany", "Germany"], "Project_ACR": ["CAstRA"], "Technology_Description": "The proposed project will significantly improve the insight in the processes that have changed a comet nucleus or asteroid since their formation. These processes typically go along with activity, the observable release of gas and/or dust. Understanding the evolutionary processes of comets and asteroids will allow us to answer the crucial question which aspects of these present-day bodies still provide essential clues to their formation in the protoplanetary disc of the early solar system. ", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2018-03-01"], "Project_ID": ["757390"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["FREIE UNIVERSITAET BERLIN", "FREIE UNIVERSITAET BERLIN"], "EU_Contribution": ["EUR 1 373 022"], "Project_Title": ["Protest and Order. Democratic theory, contentious politics, and the changing shape of western democracies"], "Total_Cost": ["EUR 1 373 022"], "Country": ["Germany", "Germany"], "Project_ACR": ["POWDER"], "Technology_Description": "The research project aims to analyze the interrelationship between protest and political order under the contextual conditions of the changing shape of modern western democracy. Two groups of ques-tions are connected to this study perspective, which will be answered by means of a democratic-theoretically-led synchronous comparison of selected contemporary protest movements \u2013 anonymous digi-tal protest movements, transnationally organized alter-globalization protest movements, the No Border movement and the rightwing identitarian protest movement: The aim is to clarify firstly (1) the extent to which the new forms of protest question the premises of democratic orders, what potential for further de-velopment lies within the new forms of protest on the one hand, and what are the challenges to democracy on the other. Secondly, the aim is to determine (2) the influence and relevance held by the democratic order itself in an age of the changing shape of democracy with regard to the specific formation of the new forms of protest, and what statements can be made on how the formation of the order is changed, in turn, by the new forms of protest themselves. In order to achieve these study perspectives, POWDER consists of an overarching democratic-theoretical framework project (TFP) and four empirical subprojects (SP 1-4), which each analyze one of the protest movements mentioned in the context of a qualitative approach (documentary analysis, participatory observation, qualitative interviews). The comparison of these protest movements investigates (I) recurring patterns, but also contrasting assessments with regard to the interre-lationship between the political order and the protest movements, examines at a second level (II) the dif-ferent manners in which the new forms of protest challenge democratic-theoretical dimensions, and at-tempts at the third level (III) to reconstruct a general democratic-theoretical determination of meaning of present-day protest movements.", "To": ["2023-03-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-04-01"], "Project_ID": ["757452"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["EBERHARD KARLS UNIVERSITAET TUEBINGEN", "EBERHARD KARLS UNIVERSITAET TUEBINGEN"], "EU_Contribution": ["EUR 1 498 216"], "Project_Title": ["Chromatin Packing and Architectural Proteins in Plants"], "Total_Cost": ["EUR 1 498 216"], "Country": ["Germany", "Germany"], "Project_ACR": ["CHROMATADS"], "Technology_Description": "The three-dimensional organization of the genome, which strikingly correlates with gene activity, is critical for many cellular processes. The evolution of molecular techniques has allowed us to unveil chromatin structure at an unprecedented resolution. The most intriguing chromatin structures observed in animals are TADs (Topologically Associating Domains), which represent the functional and structural chromatin domains demarcating the genome. Structural proteins such as insulators proteins, on the other hand, have been shown to play crucial roles in mediating the formation of TADs. However, major structural factors relevant to chromatin structure are still waiting to be discovered in land plants. My preliminary work shows that TADs are widely distributed across the rice genome, and motif sequence analysis suggests the enrichment of plant-specific transcription factors at TAD boundaries, which jointly give rise to an exciting hypothesis that these proteins might be the long-sought-after insulators in land plants. By using various state-of-the-art molecular and computational tools, this timely project aims to fill a huge gap in plant functional genomics and substantially advance our understanding of three-dimensional chromatin structure. This project consists four major aims, which collectively will uncover the identities of plant insulator proteins and generate insights into the dynamics of structural chromatin domains during stress adaptation. Aim 1 will identify and characterize the stability and plasticity of functional chromatin domains in the rice genome during temperature stress adaptation. Aim 2 will identify insulator elements and other structural features of chromatin packing in the Marchantia polymorpha genome from a structural genomics approach. Aim 3 will establish the role of candidate proteins as plant insulators. Lastly, Aim 4 will generate functional insights into the molecular mechanism by which plant insulators shape the three-dimensional genome.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["757600"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["HUMANITAS UNIVERSITY"], "EU_Contribution": ["EUR 262 269"], "Project_Title": ["Circadian Control of Histone Methylation Dynamics through the Fine-tuning of Methionine Metabolic Flux"], "Total_Cost": ["EUR 262 269"], "Country": ["Italy"], "Project_ACR": ["MetEpiClock"], "Technology_Description": "The circadian clock directs almost all aspects of diurnal physiology, including metabolism. Defects in circadian rhythms influence physiology and behavior with implications for numerous pathological conditions, including cancer, metabolic syndrome, obesity, diabetes and cardiovascular diseases. By controlling metabolic homeostasis at the cellular level, the clock can directly influence cellular regulatory networks, including those that govern chromatin dynamics. The goal of this proposal is to investigate if metabolic pathways able to influence gene expression via chromatin dynamics are under circadian control and whether these regulatory networks are crucial for the maintenance of a correct metabolic homeostasis. We will test if the clock governs the \u201cmethylation potential\u201d of the cell by regulating the diurnal expression of rate-limiting enzymes of methionine metabolism. By using metabolite restriction, pharmacological and gene editing approaches we will disrupt circadian rhythmicity of SAM and SAH. We will then use state-of-the-art methods including, transcriptomics, epigenomics and metabolomics to investigate the impact of this regulatory network on circadian transcriptional regulation, histone methylation dynamics and metabolic homeostasis. By dissecting how circadian regulation, metabolism and epigenetics are interconnected we will gain novel insights into how these factors contribute to normal physiology and disease.", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["749869"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE"], "EU_Contribution": ["EUR 1 982 925"], "Project_Title": ["mechanical BEhavior of Fluid-INduced Earthquakes"], "Total_Cost": ["EUR 1 982 925"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["BEFINE"], "Technology_Description": "Fluids play an important role in fault zone and in earthquakes generation. Fluid pressure reduces the normal effective stress, lowering the frictional strength of the fault, potentially triggering earthquake ruptures. Fluid injection induced earthquakes (FIE) are direct evidence of the effect of fluid pressure on the fault strength. In addition, natural earthquake sequences are often associated with high fluid pressures at seismogenic depths. Although simple in theory, the mechanisms that govern the nucleation, propagation and recurrence of FIEs are poorly constrained, and our ability to assess the seismic hazard that is associated with natural and induced events remains limited. This project aims to enhance our knowledge of FIE mechanisms over entire seismic cycles through multidisciplinary approaches, including the following: ", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["757290"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["CENTRO INTERNAZIONALE DI ALTISTUDI AGRONOMICI MEDITERRANEI", "CONSIGLIO NAZIONALE DELLE RICERCHE", "UNIVERSITA DEGLI STUDI DI BARI ALDO MORO", "CENTRO DI RICERCA, SPERIMENTAZIONE E FORMAZIONE IN AGRICOLTURA BASILE CARAMIA", "INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "INSTITUTO VALENCIANO DE INVESTIGACIONES AGRARIAS", "UNIVERSITE CATHOLIQUE DE LOUVAIN", "NATURAL ENVIRONMENT RESEARCH COUNCIL", "RUSSELL IPM LTD", "BENAKI PHYTOPATHOLOGICAL INSTITUTE", "MEDITERRANEAN AGRONOMIC INSTITUTE OF CHANIA", "INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE DE TUNISIE"], "EU_Contribution": ["EUR 1 777 500"], "Project_Title": ["Capacity Building And Raising Awareness In Europe And In Third Countries To Cope With Xylella fastidiosa"], "Total_Cost": ["EUR 1 777 500"], "Country": ["Italy", "Italy", "Italy", "Italy", "France", "Spain", "Spain", "Belgium", "United Kingdom", "United Kingdom", "Greece", "Greece", "Tunisia"], "Project_ACR": ["CURE-XF"], "Technology_Description": "CURE-FX aims to establish a multidisciplinary research program to answer the urgent need to improve prevention, early detection and control of Xylella fastidiosa (Xf). An appropriate approach to this emergency should include a coordination and multidisciplinary interaction between a plurality of competences and it can be facilitated by a more intense exchange and mobility of researchers.The objectives of CURE-FX are: To exchange the scientific capacities and novelties among the European Countries as well as between EU and third countries, in particular sensitive neighbor countries. To strengthen the knowledge and the know-how on Xf in third countries having intense exchange of plant material with Europe. To raise awareness in relation to Xf. These objectives will be acheived through: Strengthen preventive measures by consolidating expertise and awareness of plant health agencies, decision-makers and relevant stakeholders; Analyze Xf-hosts interaction and epidemiology; Develop advanced diagnostic tools for the detection and characterization of Xf and associated vectors; Consolidate innovative approaches for disease prevention, monitoring and control; Improving pest risk analysis, phytosanitary legislations and contingency measures for a safe plant material trade and Integrating with current platforms for adequate communication and dissemination ensuring an effective knowledge transfer among the various actors involved. The proposal involves partners from the following countries: Italy, France, Greece, Spain, Belgium, UK, Egypt, Morocco, Tunisia, Lebanon and Iran. Partner countries selected are differently involved in the study and management of quarantine pests, although each one with a different role, approach and competence. These countries can be divided into two groups: Group 1: countries where the disease is already present (Italy, France, Iran); Group 2: the other countries where the disease is currently absent, but the risk of its introduction is high", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Other", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["734353"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["INSTITUTO DE CIENCIAS SOCIAIS"], "EU_Contribution": ["EUR 148 635,60"], "Project_Title": ["Uncertain Power: Representing the king in the Portuguese empire (1640-1750)"], "Total_Cost": ["EUR 148 635,60"], "Country": ["Portugal"], "Project_ACR": ["UNCERTAINPOWER"], "Technology_Description": "This project aims at analysing the authority of the viceroys and governors-general - the highest representatives of the Portuguese kings \u2013 in the States of India and Brazil between 1640 and 1750 and as such, it deals with the relevance of non-formal expressions of power and authority, and their role in the efficiency of political communication. UNCERTAINPOWER seeks early expressions of the combination between formal and non-formal expressions of power and authority, namely in places where the physical presence of the main decision-makers was impossible to happen. In a world with ever-changing systems of communication, where virtual forms of power become more and more present, to offer a diachronic perspective on the uncertainties that long-distance expressions of power entail is relevant. The choice of the early-modern Portuguese empire is related with its early presence in the four parts of the world in a period when technologies of power and of communication were very different from ours. In UNCERTAINPOWER, issues that are still relevant today, such as the ways of expressing authority in very different socio-cultural contexts, the reception of this authority, as well as the links between these processes and the conservation of society will be discussed. Which were the ways chosen by Portuguese viceroys and governors to communicate their power and authority with the societies under their control? How did these royal agents exercise the prerogative of representing the royal power in an empire with a significant territorial extension and with a plurality of cultural and political realities? How did they adjust their political cultures to the local needs? How did the local contexts influence their ways of governing? And how did mobility challenge the meanings of power and authority? The more tangible outcomes of this project include 6 articles, 1 book and a virtual exhibition.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Portugal"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["749427"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["DUBLIN CITY UNIVERSITY", "FH OO FORSCHUNGS & ENTWICKLUNGS GMBH", "LINNEUNIVERSITETET", "TECHNISCHE UNIVERSITEIT EINDHOVEN", "UNIVERSITAT LINZ", "AWS-INSTITUT FUR DIGITALE PRODUKTEUND PROZESSE GGMBH", "RAIFFEISENLANDESBANK OBEROSTERREICHAG"], "EU_Contribution": ["EUR 3 869 128,44"], "Project_Title": ["Pioneering the Digital Future for Omnichannel Retail Managers"], "Total_Cost": ["EUR 3 869 128,44"], "Country": ["Ireland", "Austria", "Sweden", "Netherlands", "Austria", "Germany", "Austria"], "Project_ACR": ["PERFORM"], "Technology_Description": "The overall goal of PERFORM is to establish a European training network to prepare the next generation of Digital Retail Managers. Established Business Models need to be revised as customer behaviour is changing. Customers no longer prefer online or instore purchasing but switch between channels to suit their own personal requirements. Innovative digital technologies such as Internet of Things, Big Data, advanced analytics as well as augmented reality novel payment systems and visualisation concepts can create a unique and individual customer experience.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-01-01"], "Project_ID": ["765395"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["DANMARKS TEKNISKE UNIVERSITET", "ALBERT-LUDWIGS-UNIVERSITAET FREIBURG", "LUNDS UNIVERSITET", "FUNDACAO CALOUSTE GULBENKIAN", "ARCTICMASS EHF"], "EU_Contribution": ["EUR 1 559 675,88"], "Project_Title": ["Advanced use of mosses for biotechnological solutions"], "Total_Cost": ["EUR 1 559 675,88"], "Country": ["Denmark", "Germany", "Sweden", "Portugal", "Iceland"], "Project_ACR": ["MossTech"], "Technology_Description": "MossTech will expand the tools for green biotechnology. By using the simplest land plants, the mosses, MossTech will develop new green cell factories for the production of proteins, lipids and fine chemicals. MossTech will train 6 highly qualified ESRs in modern biotechnology with the focus on expanding the use of green cells in biotechnological applications. The consortium of three universities, one research institution and four companies together provides a strong background for training in scientific and transferable skills. ", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-10-01"], "Project_ID": ["765115"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM", "ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM"], "EU_Contribution": ["EUR 2 251 719"], "Project_Title": ["DNA Damage and Repair and its Impact on Healthy Ageing"], "Total_Cost": ["EUR 2 251 719"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["Dam2Age"], "Technology_Description": "We pioneered an initially highly controversial connection between DNA damage and (accelerated) aging. In the previous ERC grant \u2018DamAge\u2019 we reached the stage that (segmental) aging in DNA repair-deficient mice can be largely controlled. The severity of the repair defect determines the rate of segmental aging; the repair pathways affected influence which organs age fast; conditional repair mutants allow targeting accelerated aging to any organ. Importantly, we found that dietary restriction (DR), the only universal intervention known to delay aging, extends remaining life- and healthspan in progeroid Ercc1\u0394/- mutants by 200% (see Vermeij et al., Nature 2016 and fig.2). Also Xpg-/- progeroid repair mice strongly benefit from DR, generalizing this finding. The prominent Alzheimer- and Parkinson-like neurodegeneration is even retarded up to 30-fold(!) disclosing powerful untapped reserves unleashed by 30% less food, with enormous clinical potential. Also we discovered that in accelerated and normal aging gene expression declines due to accumulating stochastic transcription-blocking lesions and that DR counteracts genomic dysfunction. In Dam2Age we will focus on the cross-talk between DNA damage, aging and DR with emphasis on the relevance for normal aging, elucidate underlying mechanisms and use our unique -for DR research superior- mouse models and a variety of novel assays to search for effective nutritional-pharmacological DR mimetics. This serves as a stepping stone towards potent universal therapy for a range of repair-deficient progeroid syndromes and prevention of many aging-related diseases, most urgently dementia\u2019s, to promote sustained health.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["742426"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITETET I TROMSOE", "MATIS OHF", "HASKOLI ISLANDS", "UNIVERSITEIT UTRECHT", "THE MANCHESTER METROPOLITAN UNIVERSITY", "CENTRO TECNOLOGICO DEL MAR - FUNDACION CETMAR", "MAPIX TECHNOLOGIES LTD", "SYNTESA APS"], "EU_Contribution": ["EUR 2 724 033,96"], "Project_Title": ["Social Science Aspects of Fisheries for the 21st Century"], "Total_Cost": ["EUR 2 724 033,96"], "Country": ["Norway", "Iceland", "Iceland", "Netherlands", "United Kingdom", "Spain", "United Kingdom", "Denmark"], "Project_ACR": ["SAF21"], "Technology_Description": "SAF21 is an interdisciplinary and intersectoral network that embeds the social scientists of the future into EU fisheries management systems. It trains experts in analysis of human social behaviour for the better management of socio-ecological complex systems such as fisheries. Behaviour of fishers is complex as trust building and norms acceptance influence compliance with fishing regulations in unpredictable ways. The desired behaviour of fishers is often different from the actual subsequent one as those involved adapt to and find ways around new regulatory regimes, often with catastrophic consequences on resources. Therefore, an integrated understanding of the fine mechanisms governing fishers\u2019 behaviour in relation with the regulative processes is needed, to the benefit of decision makers, fishing industry and the environment alike. Academic research and training have insufficiently reflected this need. SAF21 will contribute to rectifying this by training researchers in using tools of the 21st century, e.g. computational sociology techniques, to analyse this topic from a multitude of angles: public understanding of fisheries, trust and norms, social and regulative norms, social marketing of fisheries norms, stakeholders interaction in different management systems and socio-economic resilience. This knowledge will initiate the development of innovative management strategies, especially when it comes to shifting to new regulatory regimes. The wide-ranging training envisaged will offer a structured doctoral training in academic and transferable skills in addition to highly intersectoral non-academic mobility opportunities. Thus, the SAF21 candidates will have the necessary skills and experience to cross disciplines and work sectors. SAF21 will provide researchers the opportunity to fulfill their scientific social responsibility at a higher level than conventional doctoral programs, by ensuring significant time and training for public engagement and outreach.", "To": ["2018-12-31, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["642080"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN", "LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN"], "EU_Contribution": ["EUR 2 499 333"], "Project_Title": ["Human interaction and the evolution of spoken accent"], "Total_Cost": ["EUR 2 499 333"], "Country": ["Germany", "Germany"], "Project_ACR": ["InterAccent"], "Technology_Description": "If a group of people were stranded on a desert island with limited contact to outside communities for a period of time, then the group would develop its own characteristic way of speaking or spoken accent. A lack of suitable data as input to an evolutionary computational model has meant that we have but a poor understanding of how spoken accent emerges out of human interaction. Yet a breakthrough in this area is critical for explaining the various forces - including contact between individuals through increased migration - that shape spoken accent development ultimately leading to language diversification and change. The project remedies this deficiency by developing a model of how random, local interactions between individuals leading to group-specific spoken accents can push the sound patterns of languages between stable and changing states. The methodological innovation is that the model's predictions of how spoken accent evolves will be constrained by longitudinal observations about how it actually develops within a group of speakers over time. We seek to generalise from diverse types of data: from children growing up in remote rural communities as opposed to high-contact urban settings; from languages that differ markedly in their sound structure; and from groups of adults isolated together for several months during an Antarctic winter. The project's scientific impact is on developing a computational framework for unifying historical sound change with the cognitive mechanisms by which speech is communicated and adapted to different social settings. The further impact is on understanding how migration and exposure to other accents change the sounds of language. The long-term significance of the project is to build a computationally predictive model of the way that microscopic idiosyncrasies in how humans process speech in everyday conversations accumulate into group-level macroscopic spoken accent change leading to language diversification.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["742289"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["IDRYMA IATROVIOLOGIKON EREUNON AKADEMIAS ATHINON", "IDRYMA IATROVIOLOGIKON EREUNON AKADEMIAS ATHINON"], "EU_Contribution": ["EUR 2 355 000"], "Project_Title": ["PRECISION CARE IN SYSTEMIC AUTOIMMUNITY: AN INTEGRATED MULTI-TISSUE/LEVEL APPROACH FOR SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)"], "Total_Cost": ["EUR 2 355 000"], "Country": ["Greece", "Greece"], "Project_ACR": ["LUPUSCARE"], "Technology_Description": "Systemic lupus erythematosus (SLE) is a heterogeneous disease whereby an interplay of environmental, genetic and epigenetic factors lead to perturbation of complex biological networks culminating into diverse clinical phenotypes of varying severity. High throughput methods have allowed an \u201cinitial glimpse\u201d into pathogenesis and have laid the foundations for a molecular-based taxonomy for personalized therapy. Based on our experience with the molecular characterization of SLE, a recently completed RNA sequencing analysis of 150 patients, and our track- record of \u201cparadigm shift\u201d trials in SLE, we will integrate data from multi-tissue analyses with novel technologies to improve its diagnosis, monitoring and therapy, and ask fundamental pathogenetic questions in systemic autoimmunity. More specifically, we will design gene expression panels and \u201cexpression profile\u201d/\u201dclinical trait\u201d correlation matrices for diagnostics, personalized immunotherapy and improved clinical trial design. In a systematic multi-tissue approach, we will examine the role of somatic mutations in enhancing immune hyperactivity and the risk for lymphoma. The staggering (7-9:1) female predominance will be elucidated through elaborate genomic, epigenomic and microbiota analyses of family trios. Finally, we will be pursuing the innovative hypothesis that the fundamental abnormalities of SLE lie within the bone marrow hematopoietic stem cells (HSCs) - from which all cells that participate in the pathogenesis of SLE originate - and establish it as a unifying pathogenetic mechanism. By a combination of novel experimental analyses with single cell genomics, multi\u2013omics, humanized animal models, genome editing and an \u201corgan on-a-chip\u201d device, we will validate HSCs as a therapeutic target. The utility of SLE research extends beyond its boundaries, by providing unique insights as to how the immune system recognizes self-constituents and maintains its homeostasis, and how gender impacts on disease biology.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Greece"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["742390"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITAT ZURICH", "UNIVERSITAT ZURICH"], "EU_Contribution": ["EUR 1 362 401"], "Project_Title": ["New paradigms for correlated quantum matter:Hierarchical topology, Kondo topological metals, and deep learning"], "Total_Cost": ["EUR 1 362 401"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["PARATOP"], "Technology_Description": "Discovering, classifying and understanding phases of quantum matter is a core goal of condensed matter physics. Next to the notion of symmetry breaking phases, the concept of topological phases of matter is a prevailing theme of recent research. Topological phases are envisioned for various applications due to their universal and robust properties, such as protected conducting boundary modes, and provoke fundamental questions about the nature of many-body quantum states by providing the basis for exotic quasiparticles.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["757867"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["UNIVERSITE DE GENEVE", "UNIVERSITE DE GENEVE"], "EU_Contribution": ["EUR 2 497 525"], "Project_Title": ["Unequal Democracies"], "Total_Cost": ["EUR 2 497 525"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["UneqDems"], "Technology_Description": "The proposed research program explores the implications of rising income inequality for the political process in advanced democracies and for the policies produced by competition among political parties and organized interests. The program posits that the political implications of inequality operates through two channels: inequality influences what citizens want from government, but it also affects political participation and influence and hence, by extension, government responsiveness to the preferences of different citizens. Students of the politics of inequality have tended to focus on only one channel, to the neglect of the other. The fundamental objective of the proposed research program is to develop a unified framework that draws on both research traditions and, in so doing, addresses lacunae in each. Another objective is to explore how the political consequences of low-end inequality (growing separation of the poor from the middle class) differ from the political consequences of high-end inequality (the growing concentration of income at the very top of the income distribution). The core questions that animate the research program are \u201cmacro\u201d questions, pertaining processes and outcomes that are observed at the country level (or, in other words, the political-system level), but these questions will be addressed, in part, through analyses of individual attitudes, preferences and behavior. The latter analyses will involve a couple of original surveys, including a survey of attitudes towards the rich, as well as the use of existing national and cross-national survey data. With respect to macro-level comparisons, the research program will emphasize changes over time: changes in the structure of inequality as well as the level of inequality, changes in preferences and coalitions among citizens and organized interests and, finally, changes in income (or class) bias in democratic representation.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["741538"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["ANTERYON BV", "VRIJE UNIVERSITEIT BRUSSEL"], "EU_Contribution": ["EUR 1 011 868,56"], "Project_Title": ["Next generation Compact Lightsource And Spectrometer Systems"], "Total_Cost": ["EUR 1 011 868,56"], "Country": ["Netherlands", "Belgium"], "Project_ACR": ["xCLASS"], "Technology_Description": "Increasing health and environmental awareness of European citizens has led to an urgent demand for spectral analysis of matter. However, what is missing are novel and cost-effective methods to sense the desired analytes with high sensitivity and high reliability using small and portable devices. Moreover, there is a severe shortage in the European spectroscopy industry of graduates and PhDs with the right expertise along the complete technology supply chain for the development of such micro-spectrometer systems. Training and education in all its aspects, namely in optical modeling and design, fabrication and prototyping, measurements and characterization, sensor readout and data analysis towards proof-of concept demonstration up to industrial valorisation of the micro-spectrometer systems is crucial, but to our knowledge not offered today as a whole.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["Netherlands"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["765635"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["UNIVERSITE DE NEUCHATEL", "UNIVERSITE DE NEUCHATEL"], "EU_Contribution": ["EUR 1 997 675"], "Project_Title": ["Towards a decentred history of the Middle East: Transborder spaces, circulations, frontier effects and state formation, 1920-1946"], "Total_Cost": ["EUR 1 997 675"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["BORDER"], "Technology_Description": "While the crisis of the territorial nation-state in the Middle East has once again been brought to a head by the wars in Iraq and Syria, it cannot be simply understood as the logical consequence of an imported political construction. Based on two epistemological notions \u2013 borderlands as histoire-probl\u00e8me (history-as-problem) and the co-production of borders between state and society \u2013 this research project proposes to rethink the classical historical narrative about the emergence of the post-Ottoman Middle East. Taking its cue from trans-border phenomena and thus paying attention to the circulation of people, goods and ideas as well as to everyday encounters between local actors and state representatives, the project will be guided by four principle objectives to offer:", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["725269"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["GOETEBORGS UNIVERSITET"], "EU_Contribution": ["EUR 247 059"], "Project_Title": ["The microbial degradation and utilization of mucin by Bacteroides in ulcerative colitis"], "Total_Cost": ["EUR 247 059"], "Country": ["Sweden"], "Project_ACR": ["MUC"], "Technology_Description": "The gastrointestinal tract is colonized by a community of microbes, the microbiota, which has a significant impact on human health and nutrition. The mucus gel layer structure provides the barrier between the microbiota and the intestine preventing the occurrence of the inflammation process. Indeed, an altered microbiota (towards mucus degrading bacteria) and defects in the mucus structure have been shown to be associated with inflammatory bowel diseases, such as ulcerative colitis.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["748336"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF ST MARK & ST JOHN", "ASSOCIATION GENETHON", "PANEPISTIMIO THESSALIAS", "FONDAZIONE PER LA RICERCA BIOMEDICA AVANZATA ONLUS", "STICHTING VU", "THE UNIVERSITY OF LIVERPOOL", "CHRISTOS PAPADOPOULOS & SIA O.E.", "TZARTOS - DIAGNOSIS & RESEARCH IN NEUROIMMUNOLOGY MEDICAL LIMITED LIABILITY COMPANY", "MYOMEDIX GMBH", "DLD GESELLSCHAFT FUR DIAGNOSTIKA UND MEDIZINISCHE GERATE MBH", "EUROPEAN MOLECULAR BIOLOGY LABORATORY", "IMMUNDIAGNOSTIK AG", "UNIVERSITAT KONSTANZ", "RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG", "ZENTRALINSTITUT FUER SEELISCHE GESUNDHEIT", "University of Florida", "STELLENBOSCH UNIVERSITY"], "EU_Contribution": ["EUR 1 458 000"], "Project_Title": ["Muscle Stress Relief: An integrated research program linking together basic research on secondary myopathies in stress states to innovative translation in applied myology."], "Total_Cost": ["EUR 1 606 500"], "Country": ["United Kingdom", "France", "Greece", "Italy", "Netherlands", "United Kingdom", "Greece", "Greece", "Germany", "Germany", "Germany", "Germany", "Germany", "Germany", "Germany", "United States", "South Africa"], "Project_ACR": ["Muscle stress relief"], "Technology_Description": "A diverse variety of medical or lifestyle conditions lead to a progressive loss of muscle force by functionally impairing myofibril contractility and causing ultimately myofibril loss. Major underlying risk factors of chronic muscle force loss are ageing, inactive lifestyles, and unbalanced nutrition. Together, these factors are predicted to lead to an endemic incidence of muscle weakness both in the developed countries. Clinical research on the mechanisms involved requires a multidisciplinary approach covering aspects of ageing, metabolism, and on the humoral cross-talk of muscle with other key organs including heart, liver, kidney, and lung. To achieve this, six European groups with complementary expertise in inter-organ-cross-talk during stress-induced secondary myopathies will team-up with a leading team in the U.S. with expertise in the translation of muscle research into therapeutic interventions, and with one team from South Africa with cutting-edge expertise in the regulation of regenerative capacities in muscle. ", "To": ["2020-02-29, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["645648"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOMATERIALES- CIC biomaGUNE", "GLYCODIAG", "UNIVERSITA DEGLI STUDI DI MILANO", "UNIVERSITE GRENOBLE ALPES", "UNIVERSITE JOSEPH FOURIER GRENOBLE 1", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "STICHTING VU", "DEUTSCHES KREBSFORSCHUNGSZENTRUM", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "UNIVERSITEIT LEIDEN", "GLYCOUNIVERSE GMBH & CO KGAA", "THE UNIVERSITY OF MANCHESTER", "DC4U", "MIDATECH PHARMA ESPANA SL", "STIFTUNG TIERAERZTLICHE HOCHSCHULE HANNOVER", "STICHTING VUMC"], "EU_Contribution": ["EUR 3 811 581"], "Project_Title": ["Development of Selective Carbohydrate Immunomodulators Targeting C-type Lectin Receptors on Antigen Presenting Cells"], "Total_Cost": ["EUR 3 811 581"], "Country": ["Spain", "France", "Italy", "France", "France", "Spain", "Netherlands", "Germany", "Germany", "Netherlands", "Germany", "United Kingdom", "Netherlands", "Spain", "Germany", "Netherlands"], "Project_ACR": ["IMMUNOSHAPE"], "Technology_Description": "IMMUNOSHAPE aims at training a new generation of scientists that will be capable of combining state of the art synthesis and screening technology to develop new lead structures for highly selective glycan based multivalent immunotherapeutics for the treatment of cancer, autoimmune diseases and allergy. To this end, we have set up a training program in a unique academic-industrial environment that will educate young researchers in scientific and practical biomedical glycoscience with the final aim to produce new talent and innovation in the field and improve their career perspectives in both academic and non-academic sectors. The unique combination of 10 academic groups with expertise in automated solid-phase carbohydrate synthesis, microarray based highthroughput screening technology, tumour immunology, structural glycobiology, multivalent systems and medicinal chemistry along with 4 industrial partners active in nanomedicine, immunotherapy, medicinal device development and the fabrication of scientific instrumentation will provide a multidisciplinary and multisectorial training to 15 ESRs in biomedical glycoscience and its industrial applications.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-01-01"], "Project_ID": ["642870"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["UNIVERSITAT ZURICH", "ASTON UNIVERSITY", "UNIVERSITAET BAYREUTH"], "EU_Contribution": ["EUR 3 588 125"], "Project_Title": ["Predictive Reagent Antibody Replacement Technology"], "Total_Cost": ["EUR 3 588 125"], "Country": ["Switzerland", "United Kingdom", "Germany"], "Project_ACR": ["PRe-ART"], "Technology_Description": "Predictive Reagent Antibody Replacement Technology (PRe-ART) will create a foundational new technology platform to completely replace conventional antibody technology within medical diagnostics and basic life science research. In a multidisciplinary approach combining basic science, protein engineering and computational prediction, Pre-ART will generate non-antibody components which can be combined in an entirely modular fashion to create molecules that bind any peptide of choice. Such a biotechnological revolution is timely because of current failings in the reagent antibody market, after forty years still based on monoclonal antibodies (mAbs) to detect biomolecules, when 50% of all commercial reagent mAbs have been shown to not function correctly. ", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-01-2016-2017 - FET-Open research and innovation actions"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["764434"], "Call_for_Proposal": ["H2020-FETOPEN-1-2016-2017"]}, -{"Partners": ["INSTITUTO POLITECNICO DO PORTO", "UNIVERSITAET DUISBURG-ESSEN", "UNIVERSIDAD DE SALAMANCA", "VIRTUAL POWER SOLUTIONS SA", "NEBUSENS, S.L.", "DISCOVERGY GMBH"], "EU_Contribution": ["EUR 2 160 000"], "Project_Title": ["Enabling Demand Response for short and real-time Efficient And Market Based smart Grid Operation - An intelligent and real-time simulation approach"], "Total_Cost": ["EUR 2 385 000"], "Country": ["Portugal", "Germany", "Spain", "Portugal", "Spain", "Germany"], "Project_ACR": ["DREAM-GO"], "Technology_Description": "Smart Grid (SG) concepts are rapidly being transferred to the market and huge investments have been made in renewable based electricity generation and rolling out smart meters. However, the present state of the art does not ensure neither a good return of investment nor a sustainable and efficient power system. The work so far in the EU involves mainly larger stakeholders, namely power utilities and manufacturers more focused on production and grid resources. A closer attention to the demand side of the system is required, and especially in the interaction with the new methods for SG management.", "To": ["2019-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Portugal"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-02-01"], "Project_ID": ["641794"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["TEL AVIV UNIVERSITY", "TEL AVIV UNIVERSITY"], "EU_Contribution": ["EUR 1 345 282"], "Project_Title": ["C\u00b0 symplectic geometry"], "Total_Cost": ["EUR 1 345 282"], "Country": ["Israel", "Israel"], "Project_ACR": ["CSG"], "Technology_Description": "\"The objective of this proposal is to study \"\"continuous\"\" (or C^0) objects, as well as C^0 properties of smooth objects, in the field of symplectic geometry and topology. C^0 symplectic geometry has seen spectacular progress in recent years, drawing attention of mathematicians from various background. The proposed study aims to discover new fascinating C^0 phenomena in symplectic geometry.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["757585"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["GOETEBORGS UNIVERSITET"], "EU_Contribution": ["EUR 173 857,20"], "Project_Title": ["The Role of Neuroinflammation in Alzheimer\u2019s Disease"], "Total_Cost": ["EUR 173 857,20"], "Country": ["Sweden"], "Project_ACR": ["INFLAMM-ALZ"], "Technology_Description": "Alzheimer\u2019s disease (AD) is a major public health problem with substantial economical and social impacts worldwide. Despite intense research, the pathological mechanisms of AD are still unclear. Under homeostasis, a delicate balance is struck between disposal of pathogenic proteins by the brain\u2019s immune cells, microglia, and the inflammation produced by these cells. Indeed, during an acute activation, microglia are protective, but if microglia enter an over-activated state they can induce chronic inflammation through oxidative stress that in turn leads to neuronal damage. Thus, gaining data on the chain of events involved in microglial action is a prerequisite to understanding AD. This project is a large interdisciplinary collaborative effort involving well-established methods such as confocal imaging and transgenic zebrafish, with newly developed photopharmacological tools. Drs Kettunen, Gr\u00f8tli and Andr\u00e9asson provide the world-leading expertise required for the project. By coordinating this project, Dr Mourabit will gain invaluable experience in biomedical research, photochemistry, project management, supervision, and the production of scientific results. The novel photoresponsive probes used here will allow for photonic in vivo de/activation of microglia, generating new information on their spatiotemporal activity, in real-time. This state-of-the-art resolution of cell-tracking and control of microglial signalling will provide innovative data on the pathology of neuroinflammation. We believe this interdisciplinary team will push the boundaries of research in AD. This project has the potential to identify new treatments for AD, and influence the direction of neurobiology. This project will create a unique career opportunity for Dr Mourabit, enabling him to crossover from an environmental background to biomedical research. The marrying of such interconnected disciplines will help Dr Mourabit set the foundations of an eclectic and vibrant research group.", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["750403"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM", "ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM"], "EU_Contribution": ["EUR 149 938"], "Project_Title": ["Real-time tracking of whisker kinematics for closed-loop neuroscientific experiments"], "Total_Cost": ["EUR 149 938"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["WhiskTrackGP"], "Technology_Description": "We study the sensorimotor adaptation in the cerebellum with the whiskers of the mouse as a model system. The whiskers are a sophisticated sensorimotor apparatus with which the mouse actively profiles its immediate 3D environment by swiftly whisking. To estimate distances, orientation and texture of its surroundings, the mouse uses a \u2018maximum contact, minimum penetration\u2019 scheme, with sensorimotor decisions taking place within as little as 10 ms. This scheme imposes the main experimental challenge to whisker-based studies: hair-like structures moving at high speeds need to be tracked accurately to ascribe whisker motion to cerebellar function. In order to capture the motion of the whiskers accurately, high-speed image acquisition at high frame rates (ca. 1000 fps) is required. On account of the paradigms developed to relate neural activity to whisker behavior, high-throughput and real-time whisker tracking are required. We have evaluated all presently available whisker-tracking tools that delivered the desired kinematics of whisker behavior. However, all have failed in terms of computational time and/or acquisition frequency, which rendered them unsuited both for offline use and for real-time applications. To address these limitations, we propose the commercialization of WhiskTrackGP, a high-performance image-acquisition and -processing platform for bleeding-edge neuroscientific experiments on behavior. WhiskTrackGP is a hardware-software platform that can recognize the kinematics of multiple whiskers simultaneously with minimal intervention from the experimenter. It is realized as powerful whisker-tracking software ported on a special hardware platform based on NVidia GP-GPUs and Maxeler Dataflow-Engines. We demonstrate accelerated offline video analysis in the order of 10000x (from an original processing time of 9.4 sec down to 0.9 msec). WhiskTrackGP comprises a \u201cone-stop shop\u201d solution for labs and companies active in the field of behavioral studies.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["768914"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["UNIVERSITAET BERN", "UNIVERSITAET BERN"], "EU_Contribution": ["EUR 2 500 000"], "Project_Title": ["DEVELOPMENT OF HEALTHY HOST-MICROBIAL MUTUALISM IN EARLY LIFE"], "Total_Cost": ["EUR 2 500 000"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["HHMM-Neonates"], "Technology_Description": "Background", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["742195"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["TECHNISCHE UNIVERSITEIT DELFT", "TECHNISCHE UNIVERSITEIT DELFT"], "EU_Contribution": ["EUR 1 499 941"], "Project_Title": ["SCHEDULING OF EVENT-TRIGGERED CONTROL TASKS"], "Total_Cost": ["EUR 1 499 941"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["SENTIENT"], "Technology_Description": "The advances in electronic communication and computation have enabled the ubiquity of Cyber-Physical Systems (CPS): digital systems that regulate and control all sorts of physical processes, such as chemical reactors, water distribution and power networks. These systems require the timely communication of sensor measurements and control actions to provide their prescribed functionalities. Event-triggered control (ETC) techniques, which communicate only when needed to enforce performance, have attracted attention as a mean to reduce the communication traffic and save energy on (wireless) networked control systems (NCS). However, despite ETC\u2019s great communication reductions, the scheduling of the aperiodic and largely unpredictable traffic that ETC generates remains widely unaddressed \u2013 hindering its true potential for energy and bandwidth savings.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["755953"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 2 208 618,75"], "Project_Title": ["Visualising transport dynamics of transmembrane pumps"], "Total_Cost": ["EUR 2 208 618,75"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["VisTrans"], "Technology_Description": "The project will investigate multi-component molecular machines that drive substrates across the cell envelope of bacteria. Some of the machines pump antibiotics or toxins, and so contribute to drug resistance and virulence in pathogenic strains. Questions that will be addressed include what the molecular pumps look like, how they are assembled and regulated, how they capture and translocate substrates, and the stereochemical basis for the cooperative switching of substrate-binding states. Molecular pumps that will be studied include tripartite systems driven by ATP hydrolysis, which play a central role in the efflux of macrolide antibiotics and secretion of toxins in Gram-negative bacteria, and those that use secondary transporters energized by electrochemical gradients. We will build upon our earlier observations to prepare a series of intermediates encompassing the key steps in the transport processes, to visualize tertiary and quaternary structural changes, the pathway of substrates in the efflux pumps, and the threading of toxin polypeptides through the constricted channel in the secretion assembly. The pumps and secretion systems cycle through intermediate states, and these will be studied at high resolution by cryoEM and crystallography to understand how the conformational states switch with strong cooperativity and avoid futile cycles that dissipate energy. Our work indicates that the activity of these transporters can be modulated by small peptides and potential co-factors, and we will address how these work. The project will build on our novel approach to engineer the pump assemblies that enables structural analysis at high resolution in isolation and in situ, and will be complemented with mechanistic analyses in vitro and in vivo. The project will deliver a comprehensive, structure-based description of the mechanism of drug efflux and protein translocation by transport machines and their regulation in diverse pathogenic bacteria.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["742210"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITAT ZURICH", "UNIVERSITAT ZURICH"], "EU_Contribution": ["EUR 1 008 665"], "Project_Title": ["Inequality - Public Policy and Political Economy"], "Total_Cost": ["EUR 1 008 665"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["IneqPol"], "Technology_Description": "Over the past decades, many developed countries have seen considerable increases in income and wealth inequality. Political and economic arguments for and against offsetting this rise in inequality have been put forward. This research program aims at informing this debate by developing new models that capture these trends and by analyzing their optimal policy implications, both theoretically and quantitatively. The goal is to bring together approaches from public economics, labor economics, macroeconomics, and political economy to explore whether rising inequality necessitates institutional responses and, if so, which ones. ", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["757721"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["GLOBAL LIGHTNING PROTECTION SERVICES AS", "UNIVERSITY OF SOUTHAMPTON"], "EU_Contribution": ["EUR 1 093 151,52"], "Project_Title": ["Lightning protection of wind turbine blades with carbon fibre composite materials"], "Total_Cost": ["EUR 1 093 151,52"], "Country": ["Denmark", "United Kingdom"], "Project_ACR": ["SPARCARB"], "Technology_Description": "The consortium behind SPARCARB \u2013 Global Lightning Protection Services A/S (GLPS, non-academic beneficiary), Denmark, together with the University of Southampon (SOTON, academic beneficiary entitled to award doctoral degrees), UK, and six Partner organizations \u2013 aims at providing an innovative international, interdisciplinary and intersectoral training network for four Early-Stage Researcher (ESRs), which will integrate in a single project (1) Science-based Training in material and electrical engineering; (2) Transferable Skills-based Training in carbon fibre, wind turbines, lightning protection technologies, business and innovation, and other competences; (3) and Research-based Training designed around cutting-edge challenges for the Wind Power Industry, which has identified the need for continuous research on lightning protection of large wind turbines with blades incorporating CFC structural components.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-EID - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-EID)"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["Denmark"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2015-01-01"], "Project_ID": ["642771"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["COMMUNAUTE D' UNIVERSITES ET ETABLISSEMENTS UNIVERSITE BOURGOGNE - FRANCHE - COMTE", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "FOUNDATION FOR THEORETICAL AND COMPUTATIONAL PHYSICS AND ASTROPHYSICS", "TECHNISCHE UNIVERSITAT DARMSTADT", "THE UNIVERSITY OF SUSSEX", "UNIVERSITE DE TECHNOLOGIE DE TROYES", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "QUTOOLS GMBH", "QUBIG GMBH", "TEEM PHOTONICS SA"], "EU_Contribution": ["EUR 3 833 637,12"], "Project_Title": ["Light-Matter Interfaces for Quantum Enhanced Technology"], "Total_Cost": ["EUR 3 833 637,12"], "Country": ["France", "United Kingdom", "Bulgaria", "Germany", "United Kingdom", "France", "Switzerland", "Germany", "Germany", "France"], "Project_ACR": ["LIMQUET"], "Technology_Description": "Quantum technology means the ability to organise and control the components of a functional system governed by the laws of quantum physics. The goal of this project is to train high-level young researchers through the development of innovative techniques to interface light and matter at the quantum level using atoms, nanostructures and photons, with applications in optics and quantum information processing. Well-trained and versatile researchers are needed to satisfy the demands of this rapidly growing field, in which there is also a strong drive and low threshold for industrial involvement. A prerequisite for success is the enhancement of the close connection between experimental, technological and theoretical studies. The proposed network, Light-Matter Interfaces for Quantum Enhanced Technology, LIMQUET, consists of seven academic and three industrial beneficiaries, complemented by one industrial partner. The academic partners are experienced but reasonably young groups with already established collaborations. The industrial partners have experience in developing and manufacturing high-quality components for research and industrial purposes. Within the Network, we anticipate highlights in (i) light-matter interfaces at the quantum level through the realisation of quantum networks using atoms, ions, and photons, (ii) the interfacing of light with light, in particular for light storage, (iii) adapting strategies originally developed in quantum optics to an integration into designed nanostructures, and (iv) the development of robust tools for quantum control and photonics. The training Network will enhance and use the synergy between the partners to produce a high-level doctoral training program in the field of quantum research and technology, including complementary skills and a pertinent impact of outreach activities. In order to enhance their career perspectives, all the ESRs will be jointly supervised and will be hosted on secondment by a company of the project.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-01-01"], "Project_ID": ["765075"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["UNIVERSITE D'AIX MARSEILLE"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Epigenetic control of retinoic acid-dependent genes during heart development"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["EPIGENHEART"], "Technology_Description": "EPIGENHEART proposes a unique and competitive training for heart development research centred on congenital heart diseases (CHD), a leading cause of death in Europe . Defects in the pathways involved in myocardial lineages at the venous pole of the heart are found to be the origin of CHD and atrial arrhythmias. Epigenetic gene regulation has influence in maintenance of cellular identity, differentiation, and is deregulated in many diseases. The involvement of epigenetic dysregulation in CHD is poorly described, much of the mechanistic detail involved in triggering these events in the context of heart development remains unclear. RA signalling is preferentially active in the venous pole region of the embryonic heart. A deregulation of the retinoic acid (RA) has been implicated in venous pole defects in patients. How RA signalling takes part in the genetic and epigenetic network regulating the venous pole lineage decisions needs to be studied in details. With the use of in vitro, ex vivo and in vivo approaches in transgenic and deficient mouse embryos combined with transcriptomic and chromatin profiling, the two interacting research lines of EPIGENHEART fulfils this goal. EPIGENHEART is expected to increase the knowledge on the genetic and epigenetic network regulating the formation of the venous pole, which will contribute to better understand the associated heart diseases. Apart from the impact on human health, the project will contribute to ER\u00b4s future career prospects and European scientific excellence and competitiveness.", "To": ["2017-06-30, Grant Agreement terminated |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-07-01"], "Project_ID": ["661183"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN"], "EU_Contribution": ["EUR 212 016,60"], "Project_Title": ["Processes of indigenous community resistance to large extractive projects and their struggles for autonomy in Chile and Peru"], "Total_Cost": ["EUR 212 016,60"], "Country": ["Ireland"], "Project_ACR": ["LandGrab"], "Technology_Description": "The aim of this Fellowship is for the researcher, Dr Rajiv Maher, to develop his professional capacity, advanced training, interdisciplinary skills, high-impact dissemination, and practical experience in line with the criteria for a leading independent researcher in the EU. This proposal aims to investigate the processes of indigenous community resistance to large natural resource extraction projects and their struggles for autonomy in Chile and Peru. The proposal will also examine the strategies used by companies and governments to gain community acceptance such as those relating to Corporate Social Responsibility (CSR).", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-11-01"], "Project_ID": ["707485"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["TEL AVIV UNIVERSITY", "TEL AVIV UNIVERSITY"], "EU_Contribution": ["EUR 1 499 375"], "Project_Title": ["from SPArsity to DEep learning"], "Total_Cost": ["EUR 1 499 375"], "Country": ["Israel", "Israel"], "Project_ACR": ["SPADE"], "Technology_Description": "Lately, deep learning (DL) has become one of the most powerful machine learning tools with ground-breaking results in computer vision, signal & image processing, language processing, and many other domains. However, one of its main deficiencies is the lack of theoretical foundation. While some theory has been developed, it is widely agreed that DL is not well-understood yet.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["757497"], "Call_for_Proposal": ["ERC-2017-STG"]}, -{"Partners": ["TECHNISCHE UNIVERSITAET GRAZ", "ENTRECHEM SL", "SAROMICS BIOSTRUCTURES AB", "ERNST-MORITZ-ARNDT-UNIVERSIT\u00c4T GREIFSWALD", "ENZYMICALS AG", "KUNGLIGA TEKNISKA HOEGSKOLAN", "DSM CHEMICAL TECHNOLOGY R & D BV", "VIAZYM BV", "UNIVERSIDAD DE OVIEDO", "RUHR-UNIVERSITAET BOCHUM", "UNIVERSITAET BIELEFELD", "TECHNISCHE UNIVERSITAET BRAUNSCHWEIG", "INNOSYN BV"], "EU_Contribution": ["EUR 2 787 956,64"], "Project_Title": ["BIOCASCADES- Sustainable and Scalable Biocatalytic Cascade Reactions Training Network"], "Total_Cost": ["EUR 2 787 956,64"], "Country": ["Austria", "Spain", "Sweden", "Germany", "Germany", "Sweden", "Netherlands", "Netherlands", "Spain", "Germany", "Germany", "Germany", "Netherlands"], "Project_ACR": ["BIOCASCADES"], "Technology_Description": "In BIOCASCADES, nine early-stage researchers (ESRs) will investigate the development of sustainable (chemo)enzymatic cascade reactions under the \u2018green chemistry\u2019 philosophy. The proposed BIOCASCADES project combines different techniques such as compartmentalization, protein engineering and reaction engineering in order to develop commercially viable and environmentally benign one pot reactions. By avoiding intermediate downstream- and purification-steps, cascade reactions minimize production costs, energy demand and waste production and are thus expected to make a major contribution for the development of sustainable and efficient production processes.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-EID - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-EID)"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["634200"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["UNIVERSITAETSKLINIKUM HAMBURG-EPPENDORF", "UNIVERSIDAD POMPEU FABRA", "UNIVERSITAET OSNABRUECK", "KUNGLIGA TEKNISKA HOEGSKOLAN", "GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER", "WHITEMATTER LABS GMBH", "THE UNIVERSITY OF HERTFORDSHIRE HIGHER EDUCATION CORPORATION", "PAL ROBOTICS SL"], "EU_Contribution": ["EUR 3 778 125"], "Project_Title": ["Socialising Sensori-Motor Contingencies"], "Total_Cost": ["EUR 3 778 125"], "Country": ["Germany", "Spain", "Germany", "Sweden", "Germany", "Germany", "United Kingdom", "Spain"], "Project_ACR": ["socSMCs"], "Technology_Description": "As robots become more omnipresent in our society, we are facing the challenge of making them more socially competent. However, in order to safely and meaningfully cooperate with humans, robots must be able to interact in ways that humans find intuitive and understandable. Addressing this challenge, we propose a novel approach for understanding and modelling social behaviour and implementing social coupling in robots. Our approach presents a radical departure from the classical view of social cognition as mind-reading, mentalising or maintaining internal rep-resentations of other agents. This project is based on the view that even complex modes of social interaction are grounded in basic sensorimotor interaction patterns. SensoriMotor Contingencies (SMCs) are known to be highly relevant in cognition. Our key hypothesis is that learning and mastery of action-effect contingencies are also critical to enable effective coupling of agents in social contexts. We use \u201csocSMCs\u201d as a shorthand for such socially rele-vant action-effect contingencies. We will investigate socSMCs in human-human and human-robot social interaction scenarios. The main objectives of the project are to elaborate and investigate the concept of socSMCs in terms of information-theoretic and neurocomputational models, to deploy them in the control of humanoid robots (PR2, REEM-C) for social entrainment with humans, to elucidate the mechanisms for sustaining and exercising socSMCs in the human brain, to study their breakdown in patients with autism spectrum disorders, and to benchmark the socSMCs approach in several demonstrator scenarios. Our long term vision is to realize a new socially competent robot technology grounded in novel insights into mechanisms of functional and dysfunctional social behavior, and to test novel aspects and strategies for human-robot interaction and cooperation that can be applied in a multitude of assistive roles relying on highly compact computational solutions.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["FETPROACT-2-2014 - Knowing, doing, being: cognition beyond problem solving"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["641321"], "Call_for_Proposal": ["H2020-FETPROACT-2014"]}, -{"Partners": ["TECHNISCHE UNIVERSITAET WIEN"], "EU_Contribution": ["EUR 178 156,80"], "Project_Title": ["Nanofiber-based atomic Bragg structures"], "Total_Cost": ["EUR 178 156,80"], "Country": ["Austria"], "Project_ACR": ["NanoBragg"], "Technology_Description": "In this proposal, we want to create an atomic Bragg structure by carefully adjusting the inter-atomic spacing between nanofiber-trapped atoms to approach a Bragg resonance. The structure allows to engineer the atom-nanofiber coupling for quantum-information applications. We hence build on the recent rapid progress of a novel light-matter interface based on an atomic ensemble trapped in an optical lattice created by the evanescent field of nanofiber-guided light. The small effective area of the evanescently guided light field results in a large optical depth per atom on the few-percent level. The number of atoms can easily reach several thousands for nanofibers with a length of few millimeres. In combination with the proven coherence properties, it is an ideal candidate for the implementation of fundamental building blocks for quantum information processing (QIP), such as efficient fiber-integrated quantum memories for light and optical nonlinearities on the few-photon level. However, in view of recent discoveries related to the coupling between polarization and propagation direction of the nanofiber modes, we believe that the true potential of the nanofiber system can only be unleashed by developing specialized protocols. Those protocols need to take the extraordinary polarization properties of the nanofiber-guided modes and the multilevel structure of the atoms into account. Specialized protocols will benefit from the enhanced coupling of the atoms to the nanofiber provided by the Bragg structure. We will characterize the transmission and reflection properties of the nanofiber-coupled atomic Bragg structure, with special attention to polarization effects. Subsequently we will demonstrate how the Bragg resonance can be used to enhance the spontaneous emission of the atomic array into nanofiber-guides modes with a desired propagation direction and how this significantly improves the success rate of the DLCZ quantum memory protocol.", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["658556"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["Initial conditions of exoplanet formation in protoplanetary disks"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["ICED"], "Technology_Description": "There is now a substantial population of exoplanets with well-determined masses, radii, and orbital parameters in a range of host stellar systems. JWST will bring an increase in exoplanets with atmospheric spectroscopy measurements, moving the field from pure discovery to population synthesis and characterization. Many of the best-studied planetary systems are massive and located within 1AU of their central stars; it is not clear whether all of these planets migrated from farther out in their natal disks to this location or if they could have formed in situ. Both scenarios should produce distinct compositions resulting from multiple strong, time-dependent chemical gradients in their disks due to thermal sublimation and grain processing effects. These effects likely set the bulk chemical composition of the planet\u2019s core and atmosphere, which are accreted from different material in the disk. By determining the physical conditions within 1AU, I will confirm whether they are sufficient to support in situ planet formation. I will also map the distribution of key planetary building blocks in both the solid phase (dust grains) and gas phase. This will be accomplished by interpreting disks\u2019 flux as a function of wavelength with radiative transfer models including detailed sublimation and condensation physics, and comparing observed spectral features in both the solid and gaseous phases in molecular and atomic form to those predicted by models. This project will provide training through research in numerical methods and exoplanet characterization techniques, which are important in the long term for my career goals to lead a research group in planetary formation. Through development courses, I will improve my marketability for senior research positions and in turn transfer my infrared observing skills and US and European network connections to the host. This project increases the visibility of the host and European exoplanetary astronomy on an international scale.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["749864"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF WARWICK", "THE UNIVERSITY OF WARWICK", "ECOLE DES HAUTES ETUDES EN SCIENCES SOCIALES"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["The International Register of Academic Job Categories. Facilitating Careers in the European Research Area"], "Total_Cost": ["EUR 150 000"], "Country": ["United Kingdom", "United Kingdom", "France"], "Project_ACR": ["INTAC"], "Technology_Description": "The Proof of Concept INTAC project will create a prototype of an online Register which systematically lists, explains and compares formal job categories and status positions of research- and teaching staff in 575 higher education institutions in France, Germany and Great Britain. It will set up the Register on a public multilingual platform and provide resources for career-relevant decision-making (such as career guidelines, CV templates, visualisation and mapping tools for career tracks and status systems, identifier of job equivalents, a community forum). While international academic mobility is growing at high rates and academic systems are rapidly changing, job-seekers as well as recruiting institutions often grapple with the fact that job and status categories in academic institutions (such as PRAG, Akademische R\u00e4tin or Teaching Fellow) are difficult to understand for those coming from other institutions or systems. As a consequence, academics may not recognize the most suitable career paths and academic institutions may not receive the best applications. Responding to a demand from academics, employers, unions, associations and organisations in the higher education sector, the INTAC Register aims to facilitate academic recruitments, make national and international academic job markets more transparent and help academic career planning in the European Research Area. In order to bring the Register to the market, INTAC will create a diversified revenue stream, including regular premium user fees and licensing to academic social media. Future sponsors from the public sector will be invited to commission more institutions, countries and service functions to be included into the Register. INTAC draws on the comparative research of the ERC DISCONEX (\u201cThe Discursive Construction of Academic Excellence\u201d) project on categorizations and careers of academic researchers in the UK, France, Germany and the U.S.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["754895"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Developing a Fibrosis Targeting and Tissue Reparative (FiTTeR) Therapy for the Infarcted Myocardium via an Injectable Functionalized Extracellular Matrix Hydrogel"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["FiTTeR"], "Technology_Description": "As a Marie Sk\u0142odowska-Curie Fellow, I will develop, characterize, and determine the efficacy of a biomaterial platform to target pathologic fibrosis and promote tissue repair following myocardial infarction (MI). I have an ideal background and will perform well in this project based on my expertise in extracellular matrix (ECM) derived biomaterials, characterizing the immune response to biomaterials, and evaluating in vivo outcomes. The proposed system will consist of a protein fragment tethered to an injectable hydrogel. The hydrogel carrier will be composed of ECM, which has been shown to facilitate tissue repair processes by local modulation of immune cell phenotype . The cryptic protein fragment, recently isolated and recombinantly produced by the Stevens Group , has gained attention for its ability to regulate the onset of fibrosis by interfacing with cells to abrogate the release of matrix metalloproteinases (MMPs). No therapies currently exist to prevent or mitigate fibrosis. Developing a sophisticated delivery system for a cryptic protein fragment will enable the broad potential of targeting pathologic fibrosis to be realized. This system will be advantageous in simultaneously providing localized delivery, combined immunomodulatory and regulatory properties of the ECM and recombinant protein fragment, and sustained release of the protein fragment during degradation of the ECM hydrogel. The combination of my expertise (in ECM hydrogels, characterizing the host response to biomaterials, and translating technologies) and Prof Molly Stevens\u2019s supervision and world-class interdisciplinary biomaterials-focused group, the 2014 Research Group of the Year (European Life Science Awards), at Imperial College London (ICL), together make this project ideally suited for success.", "To": ["2019-08-20, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-21"], "Project_ID": ["746980"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FREIE UNIVERSITAET BERLIN", "FREIE UNIVERSITAET BERLIN"], "EU_Contribution": ["EUR 148 500"], "Project_Title": ["EVOLchip - predicting antibiotic resistance for sustainable antibiotic stewardship"], "Total_Cost": ["EUR 148 500"], "Country": ["Germany", "Germany"], "Project_ACR": ["Evolchip"], "Technology_Description": "Antibiotic resistance is rife (fig. 1), yet notoriously difficult to predict. Here I propose to assess the applied potential of an easy to use device, \u2018EVOLchip\u2019 that allows to test antibiotic treatment schemes within a few weeks for their risk of inducing antimicrobial resistance. If successful, this would allow to use current antibiotics much longer and to reuse old antibiotics in combination. Such tests can be conducted at hospital level by any trained medical microbiologist and hence be implemented into routine antibiotic stewardship. ", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["768210"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["CENTRE INTERNATIONAL DE RECHERCHE AUX FRONTIERES DE LA CHIMIE", "CENTRE INTERNATIONAL DE RECHERCHE AUX FRONTIERES DE LA CHIMIE"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["ITO-free multi-coloured nanoscale engineered OLEDs for large-area flexible lighting and full-colour active-matrix displays"], "Total_Cost": ["EUR 150 000"], "Country": ["France", "France"], "Project_ACR": ["FlexNanoOLED"], "Technology_Description": "FlexNanoOLED aims at expanding the groundbreaking research developed within the ERC project SUPRAFUNCTION into a radically new and unprecedented technology to enable the fabrication of flexible ITO-free multi-coloured nanoscale engineered organic LEDs. In a recent breakthrough, we have developed a novel device architecture for optoelectronics which relies on a nanomesh scaffold and demonstrated its full potential by realising supramolecular nanowire photovoltaic devices with performances surpassing those of standard organic photodetectors.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-10-01"], "Project_ID": ["766936"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON", "UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 2 499 954"], "Project_Title": ["Control of cerebral blood flow by capillary pericytes in health and disease"], "Total_Cost": ["EUR 2 499 954"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["BrainEnergy"], "Technology_Description": "Pericytes, located at intervals along capillaries, have recently been revealed as major controllers of brain blood flow. Normally, they dilate capillaries in response to neuronal activity, increasing local blood flow and energy supply. But in pathology they have a more sinister role. After artery block causes a stroke, the brain suffers from the so-called \u201cno-reflow\u201d phenomenon - a failure to fully reperfuse capillaries, even after the upstream occluded artery has been reperfused successfully. The resulting long-lasting decrease of energy supply damages neurons. I have shown that a major cause of no-reflow lies in pericytes: during ischaemia they constrict and then die in rigor. This reduces capillary diameter and blood flow, and probably degrades blood-brain barrier function. However, despite their crucial role in regulating blood flow physiologically and in pathology, little is known about the mechanisms by which pericytes function.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["740427"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSIDAD POMPEU FABRA", "UNIVERSIDAD POMPEU FABRA"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Technologies for Supporting Online Music Education"], "Total_Cost": ["EUR 150 000"], "Country": ["Spain", "Spain"], "Project_ACR": ["TECSOME"], "Technology_Description": "Online learning has impacted and changed music education significantly all over the world in the last decade. Music schools and teachers have now access to a much wider audience, increasing their business opportunities specially by overcoming the geographical constraints. However, online music performance education cannot scale to MOOC level given that the student assessments rely on individual instructor review, as is the case in the well known online courses from Berklee Online. The need of a personal assessment procedure limits the growth and expansion of these courses.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["768530"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["AALTO-KORKEAKOULUSAATIO", "AALTO-KORKEAKOULUSAATIO"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Transparent and Flexible Li-Organic 3D Thin-Film Microbattery"], "Total_Cost": ["EUR 150 000"], "Country": ["Finland", "Finland"], "Project_ACR": ["TransFlexBattery"], "Technology_Description": "In this Proof-of-Concept project we will demonstrate the practical feasibility of a fundamentally novel transparent and flexible Li-organic thin-film microbattery. The strong basis for the project is the new hybrid Li-organic electrode materials discovered in the PI's ERC Advanced Grant Project \u201cMolecular-Layer-Engineered Inorganic-Organic Hybrid Materials (LAYERENG-HYBMAT)\u201d. These hybrid thin-film materials are fabricated by the combined atomic/molecular layer deposition (ALD/MLD) technique which uniquely allows for fabrication of highly conformal thin-film coatings on various flexible, sensitive, functional and/or nanostructured surfaces. Within this PoC project we will (1) design and construct an actual optimized all-ALD/MLD Li-organic battery cell, (2) confirm its optical transparency and mechanical flexibility as expected, (3) identify the most potential applications for this new type of 3D thin-film microbattery, (4) assess its real-life business opportunities, and (5) build up a network of academic and industrial collaborators for the further advancement of the novel technology.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["780041"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["UNIVERSITAET BERN", "UNIVERSITAET BERN"], "EU_Contribution": ["EUR 1 915 000"], "Project_Title": ["All-optical deconstruction of thalamic control of sleep-wake states."], "Total_Cost": ["EUR 1 915 000"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["Opto-Sleep"], "Technology_Description": "While the functions of sleep are still a matter of debate and may include memory consolidation, brain clearance, anabolism and plasticity, the neural substrates of sleep and wake states are the subject of intense study. Successive sleep-wake cycles rely on an appropriate balance between sleep-promoting nuclei of the brain located in the anterior hypothalamus and, arousal-promoting nuclei from the posterior hypothalamus and the brainstem. My laboratory identified different subsets of hypothalamic cells that controls wakefulness and rapid-eye movement (also called paradoxical) sleep using optogenetics in combination with high-density electrophysiology in freely-behaving mice. We further identified their connections with (and functional modulation of) other sleep-wake circuits throughout the brain. Although we and others have dissected important subcortical and cortical sleep-wake circuits in the brain, the precise mechanism bridging sub-cortical circuits to thalamic and cortical networks remains unclear. ", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["725850"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON", "UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 2 163 061"], "Project_Title": ["Advanced clinical photoacoustic imaging systems based on optical microresonator detection"], "Total_Cost": ["EUR 2 163 061"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["Photoclin"], "Technology_Description": "Photoacoustic imaging is widely viewed as one of the most exciting and promising biomedical imaging techniques to have emerged in recent years. It offers major opportunities for increasing our understanding of basic biological processes at an anatomical, physiological and molecular level, and for improving the clinical diagnosis and treatment of cancer and other major diseases. The aim of this project is to develop and evaluate a new generation of advanced photoacoustic scanners for clinical photoacoustic imaging based on a novel, highly sensitive, optical microresonator ultrasound sensor. This type of sensor offers the prospect of a major step forward in terms of imaging performance by providing orders of magnitude higher sensitivity than equivalently sized conventional detectors with the necessary broadband frequency response and small element size for high image quality. As a consequence, it promises greater penetration depth and improved image quality than possible with current state-of-the-art photoacoustic scanners. This will pave the way for in vivo high resolution human imaging at depths currently unattainable, opening up entirely new clinical applications in oncology, cardiovascular medicine, regenerative medicine and other areas which have hitherto been impossible due to hardware limitations. The project will involve the development of novel polymer optical microresonator sensors, advanced parallelised optical read-out schemes for real-time image acquisition, and engineering complete imaging instruments for use in clinical studies. These instruments will then be evaluated in a variety of clinical contexts including the assessment of skin cancer, head and neck cancers, cardiovascular disease and reconstructive surgery.", "To": ["2022-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["741149"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITAET BERN", "UNIVERSITAET BERN"], "EU_Contribution": ["EUR 140 625"], "Project_Title": ["Development of a compact, user-friendly and cost effective source for the generation of powerful and broad ultrashort pulses in the deep-UV"], "Total_Cost": ["EUR 140 625"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["DUVlight"], "Technology_Description": "Here we present an original design of a compact and portable set-up able to generate very broadband (70-100 nm at 300 nm) and powerful (>1uJ/pulse) ultrashort deep-UV pulses. Compared with other schemes, it guarantees an aberration-free propagation, an easy installation and minimal dispersion. The present project aims to bring the current prototype to the level of a commercial device. The conceived design will allow to manufacture a compact, portable and cost effective device, which will be user-friendly and with almost no required maintenance. ", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["768598"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["EBERHARD KARLS UNIVERSITAET TUEBINGEN", "EBERHARD KARLS UNIVERSITAET TUEBINGEN"], "EU_Contribution": ["EUR 2 496 875"], "Project_Title": ["Wide Incremental learning with Discrimination nEtworks"], "Total_Cost": ["EUR 2 496 875"], "Country": ["Germany", "Germany"], "Project_ACR": ["WIDE"], "Technology_Description": "Although homo sapiens has been endowed with language for over 50,000 years, the invention of alphabet-like scripts 3,000 years ago dominates Western linguistic thinking. Training in literacy starts in early childhood, and because of this, words and letter-like sound units can naturally seem to be the building blocks of language. The Chinese writing system highlights the cultural-specificity of this approach: characters are juxtaposed without intervening spaces, and their interpretation is highly context-dependent. Words are not singled out. And although more frequent characters contain parts indicating pronunciation, it is syllables that are referred to, not letter-like sound units.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["742545"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET", "SIMULA RESEARCH LABORATORY AS", "UNIVERSITY OF GLASGOW", "UNIVERSITEIT MAASTRICHT", "UNIVERSITAETSKLINIKUM HAMBURG-EPPENDORF", "ACESION PHARMA APS", "CLYDE BIOSCIENCES LIMITED"], "EU_Contribution": ["EUR 4 101 221,52"], "Project_Title": ["EU Training Network on Novel Targets and Methods in Atrial Fibrillation"], "Total_Cost": ["EUR 4 101 221,52"], "Country": ["Denmark", "Norway", "United Kingdom", "Netherlands", "Germany", "Denmark", "United Kingdom"], "Project_ACR": ["AFib-TrainNet"], "Technology_Description": "The AFib-TrainNet consortium will enable promising young scientists to become excellent research leaders of the future, capable of fighting the challenges that Atrial Fibrillation (AF) presents to the European population. AF is the most common sustained cardiac arrhythmia, occurring in between 1-2% of the general population. More than 6 million Europeans suffer from this arrhythmia and its prevalence is expected to increase by more than two-fold during the next 40 years due to increased life expectancy. Thus, AF is said to assume epidemic proportions. Current options for pharmacological therapy are limited by both low efficacy and side effects, including life\u2010threatening ventricular arrhythmias and severe extra-cardiac toxicities.", "To": ["2019-08-31, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-09-01"], "Project_ID": ["675351"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["KATHOLIEKE UNIVERSITEIT LEUVEN"], "EU_Contribution": ["EUR 160 800"], "Project_Title": ["Solving large systems of polynomial equations by using multi-linear algebra tools"], "Total_Cost": ["EUR 160 800"], "Country": ["Belgium"], "Project_ACR": ["TENSOROOTS"], "Technology_Description": "The modelling of real-life nonlinear processes is commonly done via local linearization, i.e., by fitting linear models to small ranges of the process. Linearization is, however, quite limited in range and model properties. A foundational step is currently being made by moving from linear to multi-linear or polynomial models to capture more general features of a nonlinear process over larger ranges. A second important development is Big Data: nowadays we often encounter high-dimensional datasets with multiple `independent\u2019 modes of variation. This increases the numbers of equations and variables and the degrees of the polynomials in the multi-linear models that are required. Big Data research is a key priority in the EU Horizon 2020 Work Programme.", "To": ["2019-08-31, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["746979"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAT ZURICH", "UNIVERSITAT ZURICH"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Neuroprotective human antibodies to the flexible tail of the prion protein"], "Total_Cost": ["EUR 150 000"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["NeuroQure"], "Technology_Description": "The misfolding of the cellular prion protein (PrPC) causes infectious neurodegenerative conditions called prion diseases. In the framework of the ERC-funded study \u201cThe Prion Protein in Health and Disease\u201d the team of Adriano Aguzzi has discovered that antibodies against the flexible tail (FT) of PrPC are neuroprotective against prion pathologies. Here we propose to clone and express such antibodies from humans and to develop them as antiprion therapeutics. The principal investigator has founded a company (www.mabylon.com) which has established a high-yield method for cloning paired heavy and light chains from human memory B cells. The proposed research program will identify rare anti-FT immunoreactive individuals among large populations by high-throughput screening. The clinical information of the selected individuals will help to identify antibodies from persons devoid of pathologies that may be related to anti-PrPC autoimmunity. Therefore, the human antibodies generated within this program will represent fast-track investigational new drug (IND) candidates with safety profiles superior to those of murine or humanized antibodies. Completion of the proposed activities will lead to the development of therapies against prion diseases, which are currently considered untreatable and invariably fatal.", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["768415"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 212 194,80"], "Project_Title": ["Understanding the role of the rainbow trout metagenome on growth and health in aquaculturally farmed fish"], "Total_Cost": ["EUR 212 194,80"], "Country": ["Denmark"], "Project_ACR": ["HappyFish"], "Technology_Description": "Aquaculture is the fastest growing food-producing sector world-wide: >50% of consumed fish are farmed and the increasing human demand for high quality protein will continue. The most important challenge for securing continued development of green aquaculture is sustainable solutions to improve feed efficiency as feed makes up >50% of the total cost for producing a fish. Further, animal protein is increasingly substituting plant based ingredients for fish feed; this has yet unknown effects on related metabolic processes affecting growth and health. Promising solutions for optimizing feed efficiency and fish health stem from recent studies that sequence metagenomes (combined microbial DNA in the host gut) to detail out how the complete gut microbiome (the microbial community in the gut) interacts with metabolic and immunological pathways in human and mice; results that have revolutionized the way we understand how microbes affects human health. Identification of beneficial bacteria holds a huge potential for optimizing feed efficiency and boost immunity in farmed fishes. The aim of this project is to pursue this potential. I will apply a multidisciplinary approach using metagenomics to describe, for the first time, the complete metagenome of the rainbow trout gut. This combined genomic resource will be coupled with carefully planned feeding experiments to identify associations with the host trout gut-microbiota and i) animal vs. plant based diets, ii) genes of the host fish, and iii) individual growth and metabolic traits such as growth rate and fat content of the host trout. Results will yield new knowledge on microbe-host interactions in rainbow trout and may lead to new products (e.g. probiotics and fish feed) enhancing fish health by actively modulating the microbiota. The project will additionally establish trout as a general model for the study of how modulation of the microbiota can give rise to increased health and meat quality in any farmed animal.", "To": ["2020-07-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-08-01"], "Project_ID": ["745723"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["LUNDS UNIVERSITET"], "EU_Contribution": ["EUR 1 674 240"], "Project_Title": ["The Translational Cancer Faster Forward doctoral programme \u2013 CanFaster"], "Total_Cost": ["EUR 3 348 480"], "Country": ["Sweden"], "Project_ACR": ["CanFaster"], "Technology_Description": "CanFaster is a joint venture among industry, health care and academia to enhance and accelerate innovations and clinical implementation within oncology. The vision of CanFaster is to prolong and save lives of cancer patients through integrated development and commercialization/implementation of diagnostic/treatment alternatives, thus reaching the market and patient more rapidly. CanFaster will save lives of cancer patients, not for future generations, but for today\u00b4s. The CanFaster programme is enabled by an intimate collaboration between industry, health care system and academia (in total ~7 million Euro will be invested), and will contribute to the Europe 2020 strategy, where one million new research jobs are needed to reach the Innovation Union flagship initiative. The collected track record of all partners in the proposed CanFaster programme demonstrates an impressive history of entrepreneurial spirit, state-of the art medical care but also truly world-class scientific excellence within translational cancer research. The CanFaster regional doctoral programme, recruiting 16 ESRs, will be hosted within CREATE Health, a translational cancer research programme with broad international collaboration partners and excellent out-put for the last 10 years. Main objectives of CanFaster are (i) Increased transnational and intersectorial mobility (ii) Intersectorial improvements through intensified collaboration within oncology between academia, industry and hospital/regional health care organisations. (iii) Acceleration of innovation, attracting international investors leading to increased number of SMEs in the region and (iv) Education of a new generation of excellent multidisciplinary, entrepreneurial scientists. This is achieved through the attraction of the MSCA program for industrial partners to add-on to the EU and public national funding of the programme with financial and in-kind contribution.", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2016 - Co-funding of regional, national and international programmes"], "Funding_scheme": ["MSCA-COFUND-DP - Doctoral programmes"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["754299"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2016"]}, -{"Partners": ["KING'S COLLEGE LONDON"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Developing new drone-based gas sensing technology to characterise fire emission plumes by miniature low cost sensors"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["FIRE-PLUME-SENSE"], "Technology_Description": "This project will deliver new drone-based gas sensing technologies for environmental monitoring, specifically to characterise the complex pollution (CO, CO2, NOx, O3 etc) plumes from wildfires. It builds on the success of these low-cost miniature sensors recently demonstrated by the ER and her industry collaborator in volcanic plumes, combined with Host expertise on fire science and remote sensing geography and partner expertise in drone applications and laboratory sensor tests. It takes timely opportunity of a major coordinated atmospheric campaign on fire plumes. Biomass burning emissions substantially influence air quality on local to regional scales as well as global atmospheric composition. Atmospheric modelling efforts to predict fire plume impacts require knowing the emission composition, which can vary greatly between different fires and also between different plume measurement altitudes, and temporally, depending on precise fuel makeup, degree of smouldering vs flaming combustion, etc. Existing approaches (ground-based, aircraft, satellite) all have limitations in quantifying the emissions, near-downwind plume height and chemical evolution. Our development of new drone-based fire plume gas sensing technology aims to fill this current \u2018data gap\u2019. There is high potential for future societal benefit through widespread applications of the new technology to detect and chemically map wildfire but also other plume hazards (e.g. volcanoes, landfill sites, industry accident releases).", "To": ["2019-01-08, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-01-09"], "Project_ID": ["706924"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["NATIONAL UNIVERSITY OF IRELAND GALWAY", "GOETEBORGS UNIVERSITET", "FUNDACION DE LA COMUNIDAD VALENCIANA CENTRO DE INVESTIGACION PRINCIPEFELIPE", "VIB", "PROTOQSAR 2000 SL", "TARBIAT MODARES UNIVERSITY (INSTRUCTOR'S TRAINING UNIVERSITY)"], "EU_Contribution": ["EUR 607 500"], "Project_Title": ["Exploiting Protein Complexes that Induce Cell-death"], "Total_Cost": ["EUR 607 500"], "Country": ["Ireland", "Sweden", "Spain", "Belgium", "Spain", "Iran"], "Project_ACR": ["EPIC"], "Technology_Description": "The formation of specific protein complexes are key events in life-and-death decisions made by cells. Inappropriate decisions underpin a plethora of disease conditions from degenerative diseases to cancer while the role of the complexes in these processes make them important therapeutic targets. Our ability to develop small molecules to target death-inducing protein complexes has been hampered by an inability to measure complex formation in cells in real-time and by the absence of robust high-throughput assays for the discovery of new lead molecules that target these complexes. ", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["690939"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE", "ROBERT KOCH-INSTITUT", "INSTITUTO NACIONAL DE SAUDE DR. RICARDO JORGE", "Department of Health", "FRIEDRICH LOEFFLER INSTITUT - BUNDESFORSCHUNGSINSTITUT FUER TIERGESUNDHEIT", "Folkh\u00e4lsomyndigheten (The Public Health Agency of Sweden)", "HELLENIC PASTEUR INSTITUTE", "INSERM - TRANSFERT SA", "PRINS LEOPOLD INSTITUUT VOOR TROPISCHE GENEESKUNDE", "SPITALUL CLINIC DR VICTOR BABES BUCURESTI - SVB", "ISTITUTO NAZIONALE PER LE MALATTIE INFETTIVE LAZZARO SPALLANZANI-ISTITUTO DI RICOVERO E CURA A CARATTERE SCIENTIFICO", "INSTITUTO DE SALUD CARLOS III", "ORSZAGOS EPIDEMIOLOGIAI KOZPONT", "MEDIZINISCHE UNIVERSITAT GRAZ", "BERNHARD-NOCHT-INSTITUT FUER TROPENMEDIZIN", "PHILIPPS UNIVERSITAET MARBURG"], "EU_Contribution": ["EUR 1 443 927"], "Project_Title": ["European Research Infrastructure on Highly Pathogenic Agents 2"], "Total_Cost": ["EUR 1 443 927"], "Country": ["France", "Germany", "Portugal", "United Kingdom", "Germany", "Sweden", "Greece", "France", "Belgium", "Romania", "Italy", "Spain", "Hungary", "Austria", "Germany", "Germany"], "Project_ACR": ["ERINHA2"], "Technology_Description": "ERINHA2 aims to complete the work carried out during the first preparatory phase (PP1) - ERINHA - in order to reach the financial, administrative and technical maturity necessary to complete the establishment of the Research Infrastructre and ensure that the operation phase can begin in 2018. ERINHA2 will therefore finalise the decision to use the status of an association and prepare the necessary legal document to register the RI depending on the country voted on to host the Central Coordinating Unit. ERINHA2 will prepare all procedures and protocols (human resources, IPR, ethics) needed to effectively operate the RI. The financial and business plans prepared in ERINHA (PP1) will updated and presented to national and international stakeholders to obtain their agreement to fund the infrastructure. An overarching group of activities - WP5, Stakeholders and commitment - will aim to accompany all partner countries in their efforts to obtain agreements and funding. This WP5 will ensure all relevant stakeholders and potential users are informed of the progress, services and benefits of ERINHA. The utlimate outcome of ERINHA2 will be the signtature of the ERINHA statutes among the founding countries to officially establish the RI and enter into the construction phase.", "To": ["2017-06-30, closed project |"], "Meta": [""], "Topic_s": ["INFRADEV-2-2015 - Preparatory Phase of ESFRI projects"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["689622"], "Call_for_Proposal": ["H2020-INFRADEV-1-2015-2"]}, -{"Partners": ["ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN", "FREIE UNIVERSITAET BERLIN", "UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "TECHNISCHE UNIVERSITAET WIEN", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "ECOLE NORMALE SUPERIEURE DE LYON", "FORSCHUNGSZENTRUM JULICH GMBH", "UNIVERSITAT DE BARCELONA", "SCIENCE AND TECHNOLOGY FACILITIES COUNCIL", "SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI DI TRIESTE", "UNIVERSITEIT VAN AMSTERDAM", "CSC-TIETEEN TIETOTEKNIIKAN KESKUS OY", "SCUOLA NORMALE SUPERIORE", "NATIONAL UNIVERSITY OF IRELAND GALWAY", "AALTO-KORKEAKOULUSAATIO"], "EU_Contribution": ["EUR 4 836 895,75"], "Project_Title": ["An e-infrastructure for software, training and consultancy in simulation and modelling"], "Total_Cost": ["EUR 4 836 896,25"], "Country": ["Switzerland", "Ireland", "Germany", "Italy", "France", "Austria", "United Kingdom", "Germany", "France", "Germany", "Spain", "United Kingdom", "Italy", "Netherlands", "Finland", "Italy", "Ireland", "Finland"], "Project_ACR": ["E-CAM"], "Technology_Description": "E-CAM will create, develop and sustain a European infrastructure for computational science applied to simulation and modelling of materials and of biological processes of industrial and societal importance. Building on the already significant network of 15 CECAM centres across Europe and the PRACE initiative, it will create a distributed, sustainable centre for simulation and modelling at and across the atomic, molecular and continuum scales. ", "To": ["2020-09-30, ongoing project |"], "Meta": [""], "Topic_s": ["EINFRA-5-2015 - Centres of Excellence for computing applications"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["676531"], "Call_for_Proposal": ["H2020-EINFRA-2015-1"]}, -{"Partners": ["EUROPEAN MOLECULAR BIOLOGY LABORATORY", "ABO AKADEMI", "CONSIGLIO NAZIONALE DELLE RICERCHE", "UNIVERSITY OF DUNDEE", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "INSTITUTO DE SALUD CARLOS III", "FUNDACIO CENTRE DE REGULACIO GENOMICA", "FUNDACION PARA EL FOMENTO DE LA INVESTIGACION SANITARIA Y BIOMEDICA DE LA COMUNITAT VALENCIANA", "INSTITUTO DE BIOLOGIA MOLECULAR E CELULAR-IBMC", "MEDZINARODNE LASEROVE CENTRUM", "USTAV MOLEKULARNI GENETIKY AKADEMIE VED CESKE REPUBLIKY VEREJNA VYZKUMNA INSTITUCE", "UNIVERSITETET I OSLO", "BIOTECHNOLOGY AND BIOLOGICAL SCIENCES RESEARCH COUNCIL", "ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM", "UNIVERSITE DE MONS", "Masarykova univerzita", "UNIVERSITEIT VAN AMSTERDAM", "INSTYTUT BIOLOGII DOSWIADCZALNEJ IM. M. NENCKIEGO POLSKIEJ AKADEMII NAUK", "WEIZMANN INSTITUTE OF SCIENCE", "UNIVERSIDADE DE COIMBRA", "ROUMEN TSANEV INSTITUTE OF MOLECULAR BIOLOGY BULGARIAN ACADEMY OF SCIENCES"], "EU_Contribution": ["EUR 1 497 910"], "Project_Title": ["Euro-BioImaging Preparatory Phase II - Project"], "Total_Cost": ["EUR 1 497 910"], "Country": ["Germany", "Finland", "Italy", "United Kingdom", "France", "Spain", "Spain", "Spain", "Portugal", "Slovakia", "Czech Republic", "Norway", "United Kingdom", "Netherlands", "Belgium", "Czech Republic", "Netherlands", "Poland", "Israel", "Portugal", "Bulgaria"], "Project_ACR": ["EuBI PPII"], "Technology_Description": "Euro-BioImaging (EuBI) is the pan-European research infrastructure project for imaging technologies in biological and medical sciences and has been on the ESFRI Roadmap since 2008. In close match with the scope and objectives of the INFRADEV2 call, Preparatory Phase II (PPII) funding will enable EuBI:", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["INFRADEV-2-2015 - Preparatory Phase of ESFRI projects"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Germany"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2016-01-01"], "Project_ID": ["688945"], "Call_for_Proposal": ["H2020-INFRADEV-1-2015-2"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "ETHNIKO IDRYMA EREVNON", "UNIVERSITY OF SURREY", "UNIVERSIDAD DE ZARAGOZA", "RENISHAW PLC", "M-SOLV LTD", "THE UNIVERSITY OF SUSSEX"], "EU_Contribution": ["EUR 3 358 044"], "Project_Title": ["Graphene-based nanomaterials for touchscreen technologies: Comprehension, Commerce and Communication"], "Total_Cost": ["EUR 3 358 044"], "Country": ["France", "Spain", "Greece", "United Kingdom", "Spain", "United Kingdom", "United Kingdom", "United Kingdom"], "Project_ACR": ["Enabling Excellence"], "Technology_Description": "\u201cEnabling Excellence\u201d offers integral R&D training at PhD level around one of the most active and exciting topics at the forefront of nanoscience and nanotechnology, graphene-based nanostructures and materials. We propose a training experience built on three interrelated pillars, namely COMPREHENSION AND CONTROL, COMMERCE, and COMMUNICATION.", "To": ["2019-03-31, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2015-04-01"], "Project_ID": ["642742"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["EUROPEAN MOLECULAR BIOLOGY LABORATORY", "ABO AKADEMI", "UNIVERSITY OF DUNDEE", "UNIVERSITA DEGLI STUDI DI TORINO", "INSTITUT CURIE", "ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM", "FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)"], "EU_Contribution": ["EUR 1 780 585"], "Project_Title": ["Global BioImaging Project - International imaging infrastructure services for the life science community"], "Total_Cost": ["EUR 1 780 585"], "Country": ["Germany", "Finland", "United Kingdom", "Italy", "France", "Netherlands", "Spain"], "Project_ACR": ["Global BioImaging"], "Technology_Description": "\"The EC H2020 funded \"\"Global BioImaging Project\"\" enables Euro-BioImaging, the research infrastructure for access to biological and medical imaging technologies on the ESFRI roadmap, to work together with its international counterparts - the Australian Microscopy and Microanalysis Research Facility (AMMRF), the National Imaging Facility (Australia) and India-BioImaging - on concrete and sustainable services for imaging infrastructure staff and users. The project is based on their signed collaboration agreements regarding the successful operation of imaging infrastructures to support research in the areas of biological and medical sciences. Euro-BioImaging together with the AMMRF, NIF and India-BioImaging will exchange best practice in imaging facility management and operation, quality management, open access policies; develop and support common training activities in infrastructure operation and cutting-edge imaging technologies for facility staff and users; develop a common virtual platform for training material on imaging technologies; develop a common virtual platform for image data analysis software. Both platforms will be openly accessible for the scientific community. ", "To": ["2018-11-30, ongoing project |"], "Meta": [""], "Topic_s": ["INFRASUPP-6-2014 - International cooperation for research infrastructures"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Germany"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2015-12-01"], "Project_ID": ["653493"], "Call_for_Proposal": ["H2020-INFRASUPP-2014-2"]}, -{"Partners": ["NATIONAL UNIVERSITY OF IRELAND GALWAY", "MEDIZINISCHE UNIVERSITAT INNSBRUCK", "LUNDS UNIVERSITET", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "DANMARKS TEKNISKE UNIVERSITET", "STICHTING KATHOLIEKE UNIVERSITEIT", "COLLAGEN SOLUTIONS (UK) LIMITED", "ORBSEN THERAPEUTICS LIMITED"], "EU_Contribution": ["EUR 3 995 083,44"], "Project_Title": ["Development of Biomaterial-based Delivery Systems for Parkinson\u2019s disease - an Integrated Pan-European Approach"], "Total_Cost": ["EUR 3 995 083,44"], "Country": ["Ireland", "Austria", "Sweden", "France", "Denmark", "Netherlands", "United Kingdom", "Ireland"], "Project_ACR": ["BrainMatTrain"], "Technology_Description": "BrainMatTrain focuses on a comprehensive understanding of Parkinson\u2019s disease (PD), from basics to translation, fully supported by 8 full partners partner organisation (4 research institutions, 2 hospitals, 2 SMEs) and one partner organisation (SME specialist in device design). This ETN will educate and train 15 Earlty Stage Researchers (ESRs) in functioanlised biomaterials, materials science, functionlisation strategies, molecular biology, stem cell biology, in vitro model systems, in vivo neuroimaging, animal models and prototype design. Recruited ESRs will receive compulsory discipline-specific, generic and complementary transferable skills training. BrainMatTrain will develop multi-modal collagen reservoir scaffolds incorporating moieties targetitng the neuroinflammatoiry and neuroprotective phases of the underlying pathology of Parkinson\u2019s disease. The researchers will undertake cross-disciplinary and intersectorial research projects, which when married together will deliver a novel, biomaterial-based, therapeutic device for the treatment of Parkinson\u2019s disease. The research training programme is designed to ensure high-calibre graduates, best placed to secure employment in the private or public sector. Fellows will experience both private and public sector research and development environments through a considered secondment plan.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-01-01"], "Project_ID": ["676408"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["AGENZIA PER LA PROMOZIONE DELLA RICERCA EUROPEA", "FUNDACAO PARA A CIENCIA E A TECNOLOGIA", "GENIKI GRAMMATIA EREVNAS KAI TECHNOLOGIAS", "DIENST VOOR WETENSCHAPPELIJKE EN TECHNISCHE INFORMATIE- SERVICE D'INFORMATION SCIENTIFIQUE ET TECHNIQUE", "OESTERREICHISCHE FORSCHUNGSFOERDERUNGSGESELLSCHAFT MBH", "DEUTSCHES ZENTRUM FUER LUFT - UND RAUMFAHRT EV", "INSTYTUT PODSTAWOWYCH PROBLEMOW TECHNIKI POLSKIEJ AKADEMII NAUK", "VEREIN EURESEARCH", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "TECHNOLOGICKE CENTRUM AKADEMIE VED CESKE REPUBLIKY", "INSTITUTO DE SALUD CARLOS III", "ETHNIKO IDRYMA EREVNON"], "EU_Contribution": ["EUR 1 996 828,50"], "Project_Title": ["Research Infrastructures Consortium for Horizon 2020"], "Total_Cost": ["EUR 2 145 266,01"], "Country": ["Italy", "Portugal", "Greece", "Belgium", "Austria", "Germany", "Poland", "Switzerland", "France", "Czech Republic", "Spain", "Greece"], "Project_ACR": ["RICH"], "Technology_Description": "The National Contact Points perform valuable services in guiding and supporting national applicants in preparing proposals for Horizon 2020 funding. We expect that through an enhanced transnational cooperation and networking between National Contact Points for research infrastructures, a higher quality of their consulting services and thus of proposals and projects can be achieved. Therefore, the specific objective of RICH (Research Infrastructures COnsortium for Horizon 2020) is to facilitate trans-national co-operation between NCPs for research infrastructures with a view to identifying and sharing good practices and raising the general standard of support to programme applicants, taking into account the diversity of actors that make up the constituency of the Research Infrastructures Part.", "To": ["2018-11-30, ongoing project"], "Meta": [""], "Topic_s": ["INFRASUPP-8-2014 - Network of National Contact Points"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Research Organisations", "Other", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations"], "From": ["2014-12-01"], "Project_ID": ["646713"], "Call_for_Proposal": ["H2020-INFRASUPP-2014-1"]}, -{"Partners": ["UNIVERSITETET I OSLO"], "EU_Contribution": ["EUR 196 400,40"], "Project_Title": ["Blending Stoichiometric and Metabolic Theories from Genes to Populations: Resource Stochiometry and Temperature Effects on Consumers with Contrasting Life-history Strategies"], "Total_Cost": ["EUR 196 400,40"], "Country": ["Norway"], "Project_ACR": ["STOICHIOMET"], "Technology_Description": "Human-induced global warming and increased nutrient bioavailability are impacting on species evolution and ecosystem functioning worldwide. Single effects of each global change factor on consumer life history have been well assessed by the metabolic theory of ecology, and ecological and biological stoichiometry, respectively, and for each biological level from genes to populations. However, their potential consequences when both interact remain elusive because of the non-additive nature of their effects. STOICHIOMET project proposes to (i) study the single and interactive effects of temperature and nutrients in food on consumer performance; and (ii) test simultaneously cornerstone concepts of both metabolic (Bergman rule) and stoichiometric theories (growth rate hypothesis; phosphorus-allocation hypothesis). To aim these, a field survey and coupled growth bioassays, following 4 (temperature) \u00d7 4 (elemental dietary composition) experimental designs, will be conducted. Consumer growth response of selected model species (Chlamydomonas, Selenastrum, Brachionus, Diaptomus, Daphnia, Drosophila) will be measured at each level in terms of: ribosomal DNA genes and intergenic spacers; genome size; nucleic acid and protein content; cell size; body size and elemental composition; and growth rates. Additional data treatment will be performed to model growth rate and coupled variables as functions of body size, temperature and resource stoichiometry, and hence, theoretically integrate metabolic and stoichiometric conceptual frameworks. Multidisciplinarity of STOICHIOMET project, interrelating genetics, biochemistry, metabolism, ecology and evolution knowledge, will contribute to the scientific development of PhD Bullejos, and together with its training programme, will favour his future re-establishment. In addition, STOICHIOMET project represents an unique opportunity to create a network among researchers from different knowledge areas and excellent European institutions.", "To": ["2019-01-08, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-10-12"], "Project_ID": ["658838"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["BIOBANKS AND BIOMOLECULAR RESOURCES RESEARCH INFRASTRUCTURE CONSORTIUM (BBMRI-ERIC)", "STICHTING KANKERREGISTER - FONDATION REGISTRE DU CANCER", "SCHWEIZERISCHER NATIONALFONDS ZUR FORDERUNG DER WISSENSCHAFTLICHEN FORSCHUNG", "MASARYKUV ONKOLOGICKY USTAV", "CHARITE - UNIVERSITAETSMEDIZIN BERLIN", "TARTU ULIKOOL", "INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE", "IDRYMA IATROVIOLOGIKON EREUNON AKADEMIAS ATHINON", "ACADEMISCH ZIEKENHUIS LEIDEN", "NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU", "WROCLAWSKIE CENTRUM BADAN EIT+ SPZOO", "KAROLINSKA INSTITUTET", "DOKUZ EYLUL UNIVERSITESI", "CENTRE INTERNATIONAL DE RECHERCHE SUR LE CANCER", "KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN", "ISTITUTO ORTOPEDICO RIZZOLI", "UNIVERSITY COLLEGE LONDON", "DEUTSCHES KREBSFORSCHUNGSZENTRUM", "FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG"], "EU_Contribution": ["EUR 4 949 448,90"], "Project_Title": ["implementAtion anD OPeration of the gateway for healTh into BBMRI-ERIC"], "Total_Cost": ["EUR 4 949 448,91"], "Country": ["Austria", "Belgium", "Switzerland", "Czech Republic", "Germany", "Estonia", "France", "Greece", "Netherlands", "Norway", "Poland", "Sweden", "Turkey", "France", "Germany", "Italy", "United Kingdom", "Germany", "Germany"], "Project_ACR": ["ADOPT BBMRI-ERIC"], "Technology_Description": "\"BBMRI-ERIC: the Biobanking and BioMolecular resources Research Infrastructure - European Research Infrastructure Consortium, aims to establish, operate and develop a Pan-European distributed research infrastructure in order to facilitate the access to biological resources as well as facilities and to support high quality biomolecular and biomedical research. ", "To": ["2018-09-30, ongoing project |"], "Meta": [""], "Topic_s": ["INFRADEV-3-2015 - Individual implementation and operation of ESFRI projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Austria"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["676550"], "Call_for_Proposal": ["H2020-INFRADEV-1-2015-1"]}, -{"Partners": ["UNIVERSITE DE BOURGOGNE", "UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK", "KOBENHAVNS UNIVERSITET", "NATIONAL UNIVERSITY OF IRELAND GALWAY", "INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE", "WAGENINGEN UNIVERSITY", "SYDDANSK UNIVERSITET", "BIOFILM CONTROL SAS", "GENXPRO GMBH"], "EU_Contribution": ["EUR 2 841 979,50"], "Project_Title": ["Training and research in Listeria monocytogenes Adaptation through Proteomic and Transcriptome deep Sequencing Analysis"], "Total_Cost": ["EUR 2 841 979,50"], "Country": ["France", "Ireland", "Denmark", "Ireland", "France", "Netherlands", "Denmark", "France", "Germany"], "Project_ACR": ["List_MAPS"], "Technology_Description": "List_MAPS is a network dedicated to the training of innovative young researchers in the field of Microbiology and Systems Biology. It focuses on Listeria monocytogenes, an ubiquitous pathogen that is in the EU the leading cause of mortality and food recalls due to foodborne pathogens, costing the EU millions of euro per annum in medical care and associated costs in the food sector. ESRs will develop scientific expertise through PhD training, mobility of researchers, summer schools, workshops and transfer-of-knowledge in the areas of Transcriptomics, Proteomics, Sequencing and Systems Biology. Working in this dynamic state-of-the-art field will provide for training of ESRs to the highest level, with co-operation and movement between academia and industry that will enhance ESR training. The overall objective of the research programme is to tackle food safety through the combination of high throughput Epigenetics, Deep sequencing of transcripts, Proteomics, Bioinformatics, Mathematics and Microbiology to decipher the transcriptional regulatory circuitry that drives adaptation and virulence of L. monocytogenes from farm to fork. This information will be exploited to understand how environmental conditions and food composition can influence GI tract adaptation/virulence and to develop an innovative transcriptome-based tool to assess in silico the virulence of large collections of isolates. This developed tool aims at replacing the currently used burdensome animal models. ", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-03-01"], "Project_ID": ["641984"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["UNIVERSITETET I OSLO", "HELSINGIN YLIOPISTO", "DANMARKS TEKNISKE UNIVERSITET", "ABO AKADEMI", "UNIVERSITAET HAMBURG", "METEO-FRANCE", "UNIVERSITETET I BERGEN", "WAGENINGEN UNIVERSITY"], "EU_Contribution": ["EUR 4 073 903,28"], "Project_Title": ["MARine MAnagement and Ecosystem Dynamics under climate change"], "Total_Cost": ["EUR 4 073 903,28"], "Country": ["Norway", "Finland", "Denmark", "Finland", "Germany", "France", "Norway", "Netherlands"], "Project_ACR": ["MARmaED"], "Technology_Description": "The proposed European Training Network, MARmaED, connects science, policy and people and transcends national borders, disciplinary barriers and sectorial divides. By building a greater knowledge base and train the next generation of scientists to think across disciplines, MARmaED contributes to reinforce Europe\u2019s position as a global leader in marine science and ensure blue growth and sustainable exploitation of marine living resources. ", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["675997"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["CENTRAL EUROPEAN RESEARCH INFRASTRUCTURE CONSORTIUM EUROPEAN RESEARCH INFRASTRUCTURE CONSORTIUM", "EUROPEAN SPALLATION SOURCE ERIC", "ASSOCIATION INTERNATIONALE EXTREME-LIGHT-INFRASTRUCTURE DELIVERY CONSORTIUM", "KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW", "TECHNISCHE UNIVERSITAET MUENCHEN", "HELMHOLTZ-ZENTRUM GEESTHACHT ZENTRUM FUR MATERIAL- UND KUSTENFORSCHUNG GMBH", "UZHGORODSKYI NACIONALNYI UNIVERSITET", "ESP CENTRAL LIMITED"], "EU_Contribution": ["EUR 3 325 755"], "Project_Title": ["ACCELERATing Europe's Leading Research Infrastructures"], "Total_Cost": ["EUR 3 325 757"], "Country": ["Italy", "Sweden", "Belgium", "Netherlands", "Germany", "Germany", "Ukraine", "United Kingdom"], "Project_ACR": ["ACCELERATE"], "Technology_Description": "CERIC-ERIC (CERIC) is a distributed research infrastructure for fundamental and applied research on novel materials and biomaterials. The RI has been in operation for 2 years and provides open access to a broad range of instruments and expertise across research communities, in order to support the research community world-wide in tackling the most challenging problems of materials research. The ACCELERATE project is proposed to support CERIC sustainability through activities of collaborative development of policies with other research infrastructures (RIs), in particular new and forming ERIC entities. ACCELERATE will assist sustainability, relevance and effectiveness of the RI through preparation of frameworks for services to private and public entities, outreach to new scientific and industrial networks and geographical areas and a methodology for RI social impact assessment. Together with the RI partners CERIC will also carry out several intense courses for development of future RI managerial, IL and TT staff. The project will be carried out while maintaining vigorous communication with research and industrial communities, policy makers, EC administration and other RI stakeholders.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["INFRADEV-03-2016-2017 - Individual support to ESFRI and other world-class research infrastructures"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Other", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Other"], "From": ["2017-01-01"], "Project_ID": ["731112"], "Call_for_Proposal": ["H2020-INFRADEV-2016-1"]}, -{"Partners": ["SCIENCE AND TECHNOLOGY FACILITIES COUNCIL", "CSC-TIETEEN TIETOTEKNIIKAN KESKUS OY", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "EUROPEAN MOLECULAR BIOLOGY LABORATORY", "SURFSARA BV", "STICHTING EGI", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "KARLSRUHER INSTITUT FUER TECHNOLOGIE", "THE UNIVERSITY OF EDINBURGH", "STICHTING LIBER", "TRUST-IT SERVICES LIMITED", "ATHINA-EREVNITIKO KENTRO KAINOTOMIAS STIS TECHNOLOGIES TIS PLIROFOFORIAS, TON EPIKOLNONION KAI TIS GNOSIS", "JISC LBG", "PARTNERSHIP FOR ADVANCED COMPUTINGIN EUROPE AISBL", "CONSIGLIO NAZIONALE DELLE RICERCHE", "ISTITUTO NAZIONALE DI FISICA NUCLEARE", "STIFTUNG DEUTSCHES ELEKTRONEN-SYNCHROTRON DESY", "ISTITUTO NAZIONALE DI GEOFISICA E VULCANOLOGIA", "BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION", "GEORG-AUGUST-UNIVERSITAT GOTTINGENSTIFTUNG OFFENTLICHEN RECHTS", "KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW", "INTEGRATED CARBON OBSERVATION SYSTEM EUROPEAN RESEARCH INFRASTRUCTURE CONSORTIUM", "GEANT VERENIGING", "ISTITUTO NAZIONALE DI ASTROFISICA", "BIOBANKS AND BIOMOLECULAR RESOURCES RESEARCH INFRASTRUCTURE CONSORTIUM (BBMRI-ERIC)", "EUROPEAN SPALLATION SOURCE ERIC", "NATURAL ENVIRONMENT RESEARCH COUNCIL", "EUROPEAN X-RAY FREE-ELECTRON LASERFACILITY GMBH", "ECRIN EUROPEAN CLINICAL RESEARCH INFRASTRUCTURE NETWORK", "THE UNIVERSITY OF MANCHESTER", "PIN SOC.CONS. A R.L. - SERVIZI DIDATTICI E SCIENTIFICI PER L UNIVERSITA DI FIRENZE", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "CINECA CONSORZIO INTERUNIVERSITARIO"], "EU_Contribution": ["EUR 9 953 067,50"], "Project_Title": ["The European Open Science Cloud for Research Pilot Project."], "Total_Cost": ["EUR 9 953 067,50"], "Country": ["United Kingdom", "Finland", "Germany", "Germany", "Netherlands", "Netherlands", "France", "Germany", "United Kingdom", "Netherlands", "United Kingdom", "Greece", "United Kingdom", "Belgium", "Italy", "Italy", "Germany", "Italy", "Spain", "Germany", "Netherlands", "Finland", "Netherlands", "Italy", "Austria", "Sweden", "United Kingdom", "Germany", "France", "United Kingdom", "Italy", "France", "Italy"], "Project_ACR": ["EOSCpilot"], "Technology_Description": "The EOSCpilot project will support the first phase in the development of the European Open Science Cloud (EOSC) as described in the EC Communication on European Cloud Initiatives [2016]. ", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["INFRADEV-04-2016 - European Open Science Cloud for Research"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations", "Other", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Other", "Other", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Other", "Other", "Research Organisations", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Research Organisations", "Other", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations"], "From": ["2017-01-01"], "Project_ID": ["739563"], "Call_for_Proposal": ["H2020-INFRADEV-2016-2"]}, -{"Partners": ["UNIVERSIDAD POLITECNICA DE MADRID", "BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION", "INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE", "FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS", "SEAGATE SYSTEMS UK LIMITED", "DEUTSCHES KLIMARECHENZENTRUM GMBH", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "CA TECHNOLOGIES DEVELOPMENT SPAIN SA", "FUJITSU TECHNOLOGY SOLUTIONS GMBH", "JOHANNES GUTENBERG-UNIVERSITAT MAINZ"], "EU_Contribution": ["EUR 3 803 407,92"], "Project_Title": ["BigStorage: Storage-based Convergence between HPC and Cloud to handle Big Data"], "Total_Cost": ["EUR 3 803 407,92"], "Country": ["Spain", "Spain", "France", "Greece", "United Kingdom", "Germany", "France", "Spain", "Germany", "Germany"], "Project_ACR": ["BigStorage"], "Technology_Description": "The consortium of this European Training Network (ETN) \"BigStorage: Storage-based Convergence between HPC and Cloud to handle Big Data\" will train future data scientists in order to enable them and us to apply holistic and interdisciplinary approaches for taking advantage of a data-overwhelmed world, which requires HPC and Cloud infrastructures with a redefinition of storage architectures underpinning them - focusing on meeting highly ambitious performance and energy usage objectives.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2015-01-01"], "Project_ID": ["642963"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["INSTITUTO DE ASTROFISICA DE CANARIAS", "STIFTUNG KIEPENHEUER-INSTITUT FUER SONNENPHYSIK", "UNIVERSITY COLLEGE LONDON", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "ISTITUTO NAZIONALE DI ASTROFISICA", "UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "STOCKHOLMS UNIVERSITET", "THE QUEEN'S UNIVERSITY OF BELFAST", "LEIBNIZ-INSTITUT FUR ASTROPHYSIK POTSDAM (AIP)", "FONDAZIONE ISTITUTO RICERCHE SOLARI LOCARNO", "UNIVERSITETET I OSLO", "THE UNIVERSITY OF SHEFFIELD", "THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN", "UNIVERSITA DEGLI STUDI DI CATANIA", "SVEUCILISTE U ZAGREBU - GEODETSKI FAKULTET", "ASTRONOMICKY USTAV AVCR VVI", "ASTRONOMICAL INSTITUTE OF THE SLOVAK ACADEMY OF SCIENCES", "NATIONAL OBSERVATORY OF ATHENS", "UNIVERSITE PAUL SABATIER TOULOUSE III", "UNIVERSITAET GRAZ", "UNIWERSYTET WROCLAWSKI", "EOTVOS LORAND TUDOMANYEGYETEM"], "EU_Contribution": ["EUR 3 998 750"], "Project_Title": ["Preparatory Phase for the European Solar Telescope"], "Total_Cost": ["EUR 9 053 638,75"], "Country": ["Spain", "Germany", "United Kingdom", "Spain", "Italy", "Italy", "Germany", "Sweden", "United Kingdom", "Germany", "Switzerland", "Norway", "United Kingdom", "Ireland", "Italy", "Croatia", "Czech Republic", "Slovakia", "Greece", "France", "Austria", "Poland", "Hungary"], "Project_ACR": ["PRE-EST"], "Technology_Description": "The European Solar Telescope (EST) will be a revolutionary Research Infrastructure that will play a major role in answering key questions in modern Solar Physics. This 4-meter class solar telescope, to be located in the Canary Islands, will provide solar physicists with the most advanced state-of-the-art observing tools to transform our understanding of the complex phenomena that drive the solar magnetic activity. The principal objective of the present Preparatory Phase is to provide both the EST international consortium and the funding agencies with a detailed plan regarding the implementation of EST.", "To": ["2021-03-31, ongoing project"], "Meta": [""], "Topic_s": ["INFRADEV-02-2016 - Preparatory Phase and support to early phase of ESFRI projects"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["739500"], "Call_for_Proposal": ["H2020-INFRADEV-2016-2"]}, -{"Partners": ["UNIVERSITAETSKLINIKUM AACHEN", "FORSCHUNGSZENTRUM JULICH GMBH", "WEIZMANN INSTITUTE OF SCIENCE", "UNIVERSITAET DUISBURG-ESSEN", "SOFTWARE COMPETENCE CENTER HAGENBERG GMBH", "TEL AVIV UNIVERSITY", "THE UNIVERSITY OF SUSSEX", "KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW", "ANDOR TECHNOLOGY LIMITED", "IBIDI GMBH", "GRADIENTECH AB", "STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS"], "EU_Contribution": ["EUR 3 866 665,32"], "Project_Title": ["Research Training Network on Integrated Component Cycling in Epithelial Cell Motility"], "Total_Cost": ["EUR 3 866 665,32"], "Country": ["Germany", "Germany", "Israel", "Germany", "Austria", "Israel", "United Kingdom", "Netherlands", "United Kingdom", "Germany", "Sweden", "Netherlands"], "Project_ACR": ["InCeM"], "Technology_Description": "Cell migration (cell motility) is a fundamental biological process that is pivotal in (i) tissue formation and repair (health) and (ii) tissue invasion during carcinogenesis (disease). Understanding and controlling cell migration will have major clinical impact. Clarifying mechanisms driving cell motility has been challenging due to the complex underlying cellular mechanisms; these involve multiple components coordinated by structural, chemical and physical signals in terms of time and space. To accomplish breakthroughs in this field, researchers are needed who (i) master cutting-edge experimental techniques for monitoring the different cellular processes at high resolution and (ii) have competencies in theoretical science for integrating the resulting data sets into mechanistic mathematical models for predicting motile cell behaviour.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations"], "From": ["2015-01-01"], "Project_ID": ["642866"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["FORSCHUNGSZENTRUM JULICH GMBH", "EUROPEAN SPALLATION SOURCE ERIC", "EUROPEAN SPALLATION SOURCE ESS AB", "LUNDS UNIVERSITET", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "INTEGRATED DETECTOR ELECTRONICS AS"], "EU_Contribution": ["EUR 3 800 932,50"], "Project_Title": ["Solid-State Neutron Detector - A new Neutron Detector for High-Flux Applications"], "Total_Cost": ["EUR 3 800 932,50"], "Country": ["Germany", "Sweden", "Sweden", "Sweden", "France", "Norway"], "Project_ACR": ["SoNDe"], "Technology_Description": "The Solid-State Neutron Detector \u2013 SoNDe \u2013 project aims to develop a high-resolution neutron detector technique that will enable the construction of position-sensitive neutron detectors for high-flux sources, such as the upcoming European Spallation Source (ESS). Moreover, by avoiding the use of 3He in this detector the 3He-shortage, which might otherwise impede the construction of such large-scale facilities, can be alleviated. The main features of the envisioned detector technique are:", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["INFRADEV-1-2014 - Design studies"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-05-01"], "Project_ID": ["654124"], "Call_for_Proposal": ["H2020-INFRADEV-1-2014-1"]}, -{"Partners": ["GEIE ERCIM", "STICHTING CENTRUM VOOR WISKUNDE EN INFORMATICA", "CONSIGLIO NAZIONALE DELLE RICERCHE", "FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS", "TECHNISCHE UNIVERSITEIT DELFT", "VERENIGING EUROCRIS", "ISTITUTO NAZIONALE DI GEOFISICA E VULCANOLOGIA", "UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 4 370 000"], "Project_Title": ["A Europe-wide Interoperable Virtual Research Environment to Empower Multidisciplinary Research Communities and Accelerate Innovation and Collaboration"], "Total_Cost": ["EUR 4 370 000,25"], "Country": ["France", "Netherlands", "Italy", "Greece", "Netherlands", "Netherlands", "Italy", "Netherlands"], "Project_ACR": ["VRE4EIC"], "Technology_Description": "The VRE4EIC project addresses key data and software challenges in supporting multidisciplinary data driven sciences. These include:", "To": ["2018-09-30, ongoing project |"], "Meta": [""], "Topic_s": ["EINFRA-9-2015 - e-Infrastructures for virtual research environments (VRE)"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["France"], "Activity": ["Other", "Research Organisations", "Research Organisations", "Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555", "Higher or Secondary Education Establishments", "Other", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["676247"], "Call_for_Proposal": ["H2020-EINFRA-2015-1"]}, -{"Partners": ["KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW", "ARCHIVES GENERALES DU ROYAUME ET ARCHIVES DE L'ETAT DANS LES PROVINCES", "CENTRE D'ETUDES ET DE DOCUMENTATION GUERRE ET SOCIETES CONTEMPORAINES / HET STUDIE- EN DOCUMENTIECENTRUM OORLOG EN HEDENDAAGSE MAATSCHAPPIJ", "ZIDOVSKE MUZEUM V PRAZE", "STIFTUNG ZUR WISSENSCHAFTLICHEN ERFORSCHUNG DER ZEITGESCHICHTE - INSTITUT FUR ZEITGESCHICHTE IFZ", "KING'S COLLEGE LONDON", "YAD VASHEM THE HOLOCAUST MARTYRS AND HEROES REMEMBRANCE AUTHORITY", "THE UNITED STATES HOLOCAUST MEMORIAL MUSEUM", "BUNDESARCHIV", "THE WIENER LIBRARY INSTITUTE OF CONTEMPORARY HISTORY LBG", "International Tracing Service", "ZYDOWSKI INSTYTUT HISTORYCZNY IM. EMANUELA RINGELBLUMA", "MEMORIAL DE LA SHOAH", "WIENER WIESENTHAL INSTITUT FUR HOLOCAUST-STUDIEN - VWI", "ONTOTEXT AD", "\"INSTITUTUL NATIONAL PENTRU STUDIEREA HOLOCAUSTULUI DIN ROMANIA \"\"ELIE WIESEL\"\"\"", "MAGYARORSZAGI ZSIDO HITKOZSEGEK SZOVETSEGE TARSADALMI SZERVEZET", "INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE", "VALSTYBINIS VILNIAUS GAONO ZYDU MUZIEJUS", "DOKUMENTACNE STREDISKO HOLOKAUSTU OBCIANSKE ZDRUZENIE", "STOWARZYSZENIE CENTRUM BADAN NAD ZAGLADA ZYDOW", "FONDAZIONE CENTRO DI DOCUMENTAZIONE EBRAICA CONTEMPORANEA -CDEC - ONLUS", "THE JEWISH MUSEUM OF GREECE", "KAZERNE DOSSIN MEMORIAAL, MUSEUM EN DOCUMENTATIECENTRUM OVER HOLOCAUST EN MENSENRECHTEN"], "EU_Contribution": ["EUR 7 969 673,75"], "Project_Title": ["European Holocaust Research Infrastructure"], "Total_Cost": ["EUR 7 969 673,75"], "Country": ["Netherlands", "Belgium", "Belgium", "Czech Republic", "Germany", "United Kingdom", "Israel", "United States", "Germany", "United Kingdom", "Germany", "Poland", "France", "Austria", "Bulgaria", "Romania", "Hungary", "France", "Lithuania", "Slovakia", "Poland", "Italy", "Greece", "Belgium"], "Project_ACR": ["EHRI"], "Technology_Description": "The European Holocaust Research Infrastructure (EHRI) project seeks to transform archival research on the Holocaust. The vision of EHRI is to integrate the data, services and expertise of existing Holocaust infrastructures on an unprecedented scale. It will allow researchers from across the globe transnational and virtual access to the integrated infrastructure, and provide them with innovative digital tools and methods to (collaboratively) explore and analyse Holocaust sources. EHRI will thereby become an indispensable tool for the study of the Holocaust from a pan-European perspective. ", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["INFRAIA-1-2014-2015 - Integrating and opening existing national and regional research infrastructures of European interest"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Netherlands"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations", "Other", "Research Organisations", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Other", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Other", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Other", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Other"], "From": ["2015-05-01"], "Project_ID": ["654164"], "Call_for_Proposal": ["H2020-INFRAIA-2014-2015"]}, -{"Partners": ["UNIVERSITY OF GLASGOW", "CHALMERS TEKNISKA HOEGSKOLA AB", "AARHUS UNIVERSITET", "THE UNIVERSITY OF SUSSEX", "ULTRAHAPTICS LIMITED"], "EU_Contribution": ["EUR 2 999 870"], "Project_Title": ["Levitation with localised tactile and audio feedback for mid-air interactions"], "Total_Cost": ["EUR 2 999 870"], "Country": ["United Kingdom", "Sweden", "Denmark", "United Kingdom", "United Kingdom"], "Project_ACR": ["Levitate"], "Technology_Description": "\"This project will be the first to create, prototype and evaluate a radically new human-computer interaction paradigm that empowers the unadorned user to reach into levitating matter, see it, feel it, manipulate it and hear it. Our users can interact with the system in a walk-up-and-use manner without any user instrumentation.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-01-2016-2017 - FET-Open research and innovation actions"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["737087"], "Call_for_Proposal": ["H2020-FETOPEN-1-2016-2017"]}, -{"Partners": ["UNIVERSITETET I OSLO", "KOBENHAVNS UNIVERSITET", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "UNIVERSITE LYON 1 CLAUDE BERNARD", "FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG", "TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY", "INTERNATIONAL RESEARCH INSTITUTE OFSTAVANGER AS"], "EU_Contribution": ["EUR 4 103 572,68"], "Project_Title": ["Nano-tailoring organo-mineral materials -Controlling strength and healing with organic molecules in mineral interfaces"], "Total_Cost": ["EUR 4 103 572,68"], "Country": ["Norway", "Denmark", "United Kingdom", "France", "Germany", "Israel", "Norway"], "Project_ACR": ["NanoHeal"], "Technology_Description": "Cement production for the construction industry contributes up to 5% of anthropogenic CO2 emissions. Developing more environmentally friendly concrete requires the assessment of strength for a diverse range of new cement materials. Similar issues arise during the development of biocompatible cements for medical applications. Properties of naturally cemented materials of organic origin are of key importance in the oil industry, with carbonate reservoirs prone to creep, particularly during the injection of CO2 for enhanced oil recovery or permanent storage. However, despite the importance of cement materials to our infrastructure, health and environment, we still lack the fundamental basis for understanding the strength of cemented aggregates. Granular pastes and sediments transform to strong solids through reactions at nano-confined mineral interfaces, where nucleation and growth at the adjacent solid surfaces are affected in a manner not yet understood. There is a need for improved concepts, theories and models. ", "To": ["2018-12-31, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2015-01-01"], "Project_ID": ["642976"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["AGENCE NATIONALE DE LA RECHERCHE", "FONDS ZUR F\u00d6RDERUNG DER WISSENSCHAFTLICHEN FORSCHUNG", "FONDS NATIONAL DE LA RECHERCHE SCIENTIFIQUE", "BULGARIAN NATIONAL SCIENCE FUND", "DEUTSCHE FORSCHUNGSGEMEINSCHAFT", "INNOVATIONSFONDEN", "MINISTERIO DE ECONOMIA, INDUSTRIA Y COMPETITIVIDAD", "GENIKI GRAMMATIA EREVNAS KAI TECHNOLOGIAS", "NEMZETI KUTATASI FEJLESZTESI ES INNOVACIOS HIVATAL", "MINISTERO DELL'ISTRUZIONE, DELL'UNIVERSITA' E DELLA RICERCA", "Lietuvos mokslo taryba", "VALSTS IZGLITIBAS ATTISTIBAS AGENTURA", "STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN", "NEDERLANDSE ORGANISATIE VOOR WETENSCHAPPELIJK ONDERZOEK", "NARODOWE CENTRUM BADAN I ROZWOJU", "FUNDACAO PARA A CIENCIA E A TECNOLOGIA", "Unitatea Executiva pentru Finantarea Invatamantului Superior, a Cercetarii, Dezvoltarii si Inovarii", "VERKET F\u00d6R INNOVATIONSSYSTEM", "VETENSKAPSRADET - SWEDISH RESEARCH COUNCIL", "Ministrstvo za izobrazevanje, znanost in sport", "SLOVENSKA AKADEMIA VIED", "TURKIYE BILIMSEL VE TEKNOLOJIK ARASTIRMA KURUMU", "THE ENGINEERING AND PHYSICAL SCIENCES RESEARCH COUNCIL"], "EU_Contribution": ["EUR 6 052 612,50"], "Project_Title": ["The Flagship ERA-NET"], "Total_Cost": ["EUR 18 341 250"], "Country": ["France", "Austria", "Belgium", "Bulgaria", "Germany", "Denmark", "Spain", "Greece", "Hungary", "Italy", "Lithuania", "Latvia", "Netherlands", "Netherlands", "Poland", "Portugal", "Romania", "Sweden", "Sweden", "Slovenia", "Slovakia", "Turkey", "United Kingdom"], "Project_ACR": ["FLAG-ERA II"], "Technology_Description": "FLAG-ERA, the Flagship ERA-NET, gathers national and regional funding organisation with the goal of supporting, together with the European Commission, the FET Flagship initiatives and more generally the FET Flagship programme. Most funding organisations in Europe participate, either directly or as associated members. FLAG-ERA contributes to the construction of the two Flagship initiatives on Graphene and Human Brain research, through a range of activities such as the launch of joint calls supporting transnational projects in synergy with the Flagships, contribution to the Flagship partnering framework, identification of potential partnering projects, information on funding opportunities for the Flagships, and networking events. The activities in FLAG-ERA are organised around periodic events gathering all stakeholders and structured in sessions dedicated to the various objectives and related tasks of the project. FLAG-ERA II is the second ERA-NET project, implemented as an ERA-NET Cofund, starting in December 2016 for a period of 5 years, following the first FLA-ERA ERA-NET project which lasted from October 2013 to November 2016.", "To": ["2021-11-30, ongoing project"], "Meta": [""], "Topic_s": ["FETFLAG-01-2016 - Partnering environment for FET flagships"], "Funding_scheme": ["ERA-NET-Cofund - ERA-NET Cofund"], "Coordinated_in": ["France"], "Activity": ["Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Research Organisations", "Research Organisations"], "From": ["2016-12-01"], "Project_ID": ["730027"], "Call_for_Proposal": ["H2020-FETFLAG-01-2016"]}, -{"Partners": ["NATIONAL UNIVERSITY OF IRELAND GALWAY"], "EU_Contribution": ["EUR 175 866"], "Project_Title": ["The transnational mobility of cheap print: British chapbooks in Italy, 1800-1850"], "Total_Cost": ["EUR 175 866"], "Country": ["Ireland"], "Project_ACR": ["CHAP"], "Technology_Description": "This action proposes mobility for an Italian researcher living in Britain to work in Ireland on a transnational historico-literary project. Her research focuses on the cross-cultural transfer of cheap print between Britain and Italy in the first half of the nineteenth century. The project advances existing knowledge of popular publishing and reading in two ways. Firstly, it contributes to the European historiography of cheap publications by extending the investigation of their production, distribution and reception to the Italian context. Secondly, and most importantly, it provides a concrete idea of the cross-cultural nature of cheap literature by exploring the mechanisms which regulate its migration from one linguistic and cultural realm to another. The transnational trajectory of cheap print is investigated with a focus on translation and on its potential to establish fruitful negotiations between the literary and cultural repertoires of the source and the target context. The project examines a corpus of chapbooks translated from English into Italian published between 1800 and 1850. The Italian chapbooks and their sources are analysed using an interdisciplinary approach which integrates theories of textuality, the history of the book and of reading, and translation studies. The comparative approach followed in my study will significantly enhance our understanding of popular literature and of the processes which led to the formation of a shared European heritage of popular culture. The multidisciplinary research environment at NUIG provides the ideal conditions for the researcher to develop this project and the skills necessary for her future academic career. The collaboration of Dr Niall \u00d3 Cios\u00e1in and the training that she will undertake in the history of the book will be particularly important to integrate her familiarity with translation and the eighteenth- and nineteenth-century Italian cultural context with new knowledge of popular publishing and reading.", "To": ["2017-08-31, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["660143"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["NATIONAL UNIVERSITY OF IRELAND GALWAY"], "EU_Contribution": ["EUR 187 866"], "Project_Title": ["Engaging Urban Youth: Community, Citizenship, and Democracy"], "Total_Cost": ["EUR 187 866"], "Country": ["Ireland"], "Project_ACR": ["CMCG"], "Technology_Description": "Disadvantaged youth in urban environments often experience marginalization and disenfranchisement that can lead to disastrous consequences for them, their families, and wider society. We know that successfully engaging these young men and women in the institutions, communities, and contexts in which they live and building their capacity as social actors can be a critical factor in their positive development as individuals and future role as citizens. Yet, there is still relatively little known empirically about the specific contexts, strategies, and mechanisms through which disadvantaged urban youth can be most effectively engaged. This research is designed to develop the expertise of the experienced researcher to enable him to contribute much needed in-depth knowledge of how best to engage young people as citizens both civic and political actors with autonomy and responsibility for contributing to the common good. This work will be done through a comparative case study in three Irish cities. The methodology will involve a consultative process with designated stakeholders in each city including local politicians, policy leaders, service providers, service users, youth representatives and youth workers. It will involve field observations and interviews with young men and women in three selected case study cities, each having a distinct urban identity: Large multi-cultural (Dublin); Post-Conflict ( Belfast) and Smaller Regional City (Galway). Dissemination and Public Engagement are central to this proposal. The research will impact on the participating stakeholders by providing tangible and accessible research findings. It will impact on the field of urban youth studies by offering a comparative framework applicable to other urban contexts in Europe and globally. The impact for the experienced researcher will be the development of specific expertise with a view to developing further European and global studies of this important field.", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["661541"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["NARODOWE CENTRUM NAUKI", "FONDS ZUR F\u00d6RDERUNG DER WISSENSCHAFTLICHEN FORSCHUNG", "FONDS NATIONAL DE LA RECHERCHE SCIENTIFIQUE", "FONDS VOOR WETENSCHAPPELIJK ONDERZOEK-VLAANDEREN", "BULGARIAN NATIONAL SCIENCE FUND", "MINISTRY OF EDUCATION YOUTH AND SPORTS", "INNOVATIONSFONDEN", "SUOMEN AKATEMIA", "AGENCE NATIONALE DE LA RECHERCHE", "BUNDESMINISTERIUM FUER BILDUNG UND FORSCHUNG", "VDI TECHNOLOGIEZENTRUM GMBH", "GENIKI GRAMMATIA EREVNAS KAI TECHNOLOGIAS", "NEMZETI KUTATASI FEJLESZTESI ES INNOVACIOS HIVATAL", "SCIENCE FOUNDATION IRELAND SFI", "MATIMOP - THE ISRAELI CENTER FOR R&D", "MINISTERO DELL'ISTRUZIONE, DELL'UNIVERSITA' E DELLA RICERCA", "CONSIGLIO NAZIONALE DELLE RICERCHE", "VALSTS IZGLITIBAS ATTISTIBAS AGENTURA", "STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN", "NORGES FORSKNINGSRAD", "NARODOWE CENTRUM BADAN I ROZWOJU", "FUNDACAO PARA A CIENCIA E A TECNOLOGIA", "Unitatea Executiva pentru Finantarea Invatamantului Superior, a Cercetarii, Dezvoltarii si Inovarii", "SLOVENSKA AKADEMIA VIED", "Ministrstvo za izobrazevanje, znanost in sport", "MINISTERIO DE ECONOMIA, INDUSTRIA Y COMPETITIVIDAD", "VETENSKAPSRADET - SWEDISH RESEARCH COUNCIL", "SCHWEIZERISCHER NATIONALFONDS ZUR FORDERUNG DER WISSENSCHAFTLICHEN FORSCHUNG", "TURKIYE BILIMSEL VE TEKNOLOJIK ARASTIRMA KURUMU", "THE ENGINEERING AND PHYSICAL SCIENCES RESEARCH COUNCIL", "The Technology Strategy Board", "OESTERREICHISCHE FORSCHUNGSFOERDERUNGSGESELLSCHAFT MBH"], "EU_Contribution": ["EUR 11 510 008,29"], "Project_Title": ["QuantERA ERA-NET Cofund in Quantum Technologies"], "Total_Cost": ["EUR 39 783 228"], "Country": ["Poland", "Austria", "Belgium", "Belgium", "Bulgaria", "Czech Republic", "Denmark", "Finland", "France", "Germany", "Germany", "Greece", "Hungary", "Ireland", "Israel", "Italy", "Italy", "Latvia", "Netherlands", "Norway", "Poland", "Portugal", "Romania", "Slovakia", "Slovenia", "Spain", "Sweden", "Switzerland", "Turkey", "United Kingdom", "United Kingdom", "Austria"], "Project_ACR": ["QuantERA"], "Technology_Description": "QuantERA ERA-NET Cofund in Quantum Technologies", "To": ["2021-10-31, ongoing project"], "Meta": [""], "Topic_s": ["FETPROACT-03-2016 - FET ERANET Cofund in Quantum Technologies"], "Funding_scheme": ["ERA-NET-Cofund - ERA-NET Cofund"], "Coordinated_in": ["Poland"], "Activity": ["Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2016-11-01"], "Project_ID": ["731473"], "Call_for_Proposal": ["FETPROACT-2016"]}, -{"Partners": ["BCAM - BASQUE CENTER FOR APPLIED MATHEMATICS"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Derivation of Effective Dynamics from Microscopic Evolution Equations"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["DEDMEE"], "Technology_Description": "The derivation of macroscopic (effective) equations from microscopic considerations is a long-standing challenge of the mathematical analysis of many-body problems. In this research proposal, we focus on the derivation of (linear or non-linear) kinetic and Hartree-type equations from microscopic quantum models. ", "To": ["2017-05-31, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2015-06-01"], "Project_ID": ["660021"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITAET ZU KOELN"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Freedom of Teaching and Political Control:The Case of Thomas Aquinas\u2019 Assimilation in William of Peter Godin\u2019s Lectura Thomasina (14th C.)"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["TEACHPOL"], "Technology_Description": "The project intends to explore the speculative, historical, and political functions assumed by William of Peter Godin\u2019s Lectura thomasina in the assimilation and teaching of Thomas Aquinas\u2019 doctrines after the series of condemnations, censures, and corrections promulgated by some political authorities between the end of the 13th and the beginning of the 14th century. The text, still unpublished and preserved in fifteen manuscripts, does not represent a mere collection of Thomas\u2019 dicta, but rather a sort of authorized handbook for students, which frequently replaced the direct lecture of Aquinas\u2019 texts. In line with the educational policies, but true to Thomas\u2019 intentions, the Lectura thomasina is an outstanding multidisciplinary document: it harmonizes speculative contents from Thomas Aquinas\u2019 texts with political pressures and religious convinctions.", "To": ["2017-05-14, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-05-15"], "Project_ID": ["657033"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["NATIONAL UNIVERSITY OF IRELAND GALWAY"], "EU_Contribution": ["EUR 175 866"], "Project_Title": ["The Application of Advanced Raman Spectroscopies to the Quantitative Analysis of Industrial Chromatography Columns"], "Total_Cost": ["EUR 175 866"], "Country": ["Ireland"], "Project_ACR": ["RICC"], "Technology_Description": "Dr. Kevin Buckley (KB) was awarded his PhD from University College London (UCL) in 2011. At UCL he had worked to develop Raman spectroscopy as a tool for bone-disease diagnosis and he subsequently took a position as a Laser Spectroscopy Scientist, at the Rutherford Appleton Lab (RAL) in Oxfordshire, England, to continue this work. After leaving RAL, KB moved to the University of British Columbia (UBC) in Vancouver, Canada. At UBC he worked to develop a Raman spectroscopy-based instrument for detecting chemical changes in (donated) human red blood cells as they age in plastic blood-bags. He has recently (Aug 2015) returned to his home country of Ireland and the primary aim of the proposed Marie Sk\u0142odowska-Curie Fellowship is to reintegrate him with the research community there. The primary scientific objectives of the fellowship to develop novel analytical methods based on Spatially Offset Raman Spectroscopy (SORS) for applications in biopharmaceutical manufacturing. It is proposed that this interdisciplinary research take place under the supervision of Dr. Alan Ryder (AR) in the Nanoscale Biophotonics Lab (NBL) at the National University of Ireland, Galway. The combination of KB\u2019s SORS expertise with AR\u2019s biopharma expertise has the potential to deliver innovative science; KB is one of the few researchers in the world who has years of experience with SORS of complex materials (he trained under the inventor of SORS, Prof. P. Matousek FRSC, at RAL) and AR is an international leader in the development of quantitative analytical methods for biopharmaceutical manufacturing processes. In addition to scientific objectives, the fellowship programme has been designed to develop KB\u2019s career and enhance his ability as a scientist. He will be provided with opportunities to develop academic teaching skills and will prepare a specific career development strategy. AR will also mentor KB as he prepares post-fellowship grant proposals and begins his independent academic career.", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["705249"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE UNIVERSITY OF SUSSEX"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Structural and Functional Studies of ATRX- Syndrome Protein"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SFSASP"], "Technology_Description": "The eukaryotic genome is packaged into chromatin, which needs to be unpacked to provide necessary access by cellular factors for varied cellular functions. However, DNA can be rendered accessible by the action of energy-consuming chromatin remodelling proteins. One such protein is ATRX that harbours an N-terminal plant homeodomain (PHD) and a C-terminal helicase domain that confers ATPase activity and identifies ATRX as a member of the snf2 family member of chromatin remodellers. ATRX has been shown to localize in vivo with constitutive heterochromatin in pericentromeric regions as well as telomeres where it works in complex with DAXX for the deposition of the Histone3.3. Mutations in the ATRX gene give rise to ATR-X syndrome, a severe X-linked mental retardation syndrome often accompanied by alpha-thalassemia. Mounting evidence links ATRX mutations to cancer and to malignancies that depend on a telomerase-independent pathway of telomere maintenance called the \u2018alternative lengthening of telomeres (ALT) pathway, linking ATRX to aging. Despite these advances however, there is lack of understanding of the molecular mechanism of ATRX and of its role within these pathologies. The proposed research aims to investigate the structural and functional properties of ATRX, and to define at a molecular level how it interacts with DAXX to remodel chromatin. We will use a combination of biophysical techniques like NMR, Isothermal Calorimetry and western blotting to characterize ATRX interaction with partner proteins. X-ray crystallography, Cryo-electron microscopy and Small angle X-ray scattering techniques will be used to elucidate the structure of ATRX complexes. We will also design assays to measure the enzymatic activity of the ATRX snf2 domain by itself and in presence of DNA and/or its interacting partners. These studies will provide insight into a potential new mechanism of chromatin remodelling and will help us elucidate the consequences of disease-related ATRX mutations.", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["660349"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITETET I OSLO"], "EU_Contribution": ["EUR 208 400,40"], "Project_Title": ["Bacterial Adhesion Control through Surface TArgeted Regulation"], "Total_Cost": ["EUR 208 400,40"], "Country": ["Norway"], "Project_ACR": ["BAC-STAR"], "Technology_Description": "Fundamental investigations of bacterial adhesion will create the knowledge base to advance surface engineering approaches.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["704903"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITY OF CENTRAL LANCASHIRE"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Black Women/Black Nationalism \u2013 Feminist Discourses on Nation-building in American and British Literature and Visual Arts"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["BWBN"], "Technology_Description": "My research aims to make a significant contribution to the scholarship on contemporary Black women artists in the US & the UK. It will pose a polemical formulation of Black feminist literature and visual arts of the 1980s and 90s in light of postcolonial scholarship. These two decades saw a flowering of talent of Black British and American women: in the US they are described as Black Women\u2019s Renaissance and in the UK as Black Arts Movement. Both movements came to fruition in the aftermath of civil rights and feminist struggles of black people in the US and UK. This project will investigate how the work of African American and Black British female artists reflected interaction and intersection of cultural nationalism and black feminism. It will demonstrate that feminist narratives and artworks of that period, usually not associated with black cultural nationalism, played a pivotal role in the continuation of indigenous cultural politics of Black cultural nationalism, which came to being in the 1960s and 70s in the US. During that period African American art strove to validate black culture as a culture possessing its own ideas and forms of aesthetic expression. The cause of BCN was propelled through the veneration of Black values, sensibilities, symbols, and rituals, which, as this project will argue, became also central to the identity politics of the artists of Black Women Renaissance and Black Arts Movement in the decades that followed. My project will demonstrate that this strategy of validating black culture, which was so empowering in the 1960s and 70s, ultimately turned to be counter-productive for the goals of black feminism, as it created a limited number of positions from which black women\u2019s subjectivity could be articulated. UCLan with its world-class researchers in transatlantic studies (i.e. Prof. Rice) and Black Arts and black feminism (i.e. Prof. Lubaina Himid, a founder of Black Arts Movement) provides an ideal host institution.", "To": ["2018-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-08-01"], "Project_ID": ["706741"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["EUROPEAN SPALLATION SOURCE ERIC", "EUROPEAN SPALLATION SOURCE ESS AB", "CESKE VYSOKE UCENI TECHNICKE V PRAZE", "KOBENHAVNS UNIVERSITET", "TEKNOLOGISK INSTITUT", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "INSTITUT MAX VON LAUE - PAUL LANGEVIN", "FORSCHUNGSZENTRUM JULICH GMBH", "MAGYAR TUDOMANYOS AKADEMIA WIGNER FIZIKAI KUTATOKOZPONT", "ELETTRA - SINCROTRONE TRIESTE SCPA", "ISTITUTO NAZIONALE DI FISICA NUCLEARE", "TECHNISCHE UNIVERSITEIT DELFT", "CONSORCIO PARA LA CONSTRUCCION, EQUIPAMIENTO Y EXPLOTACION DE LA SEDE ESPANOLA DE LA FUENTE EUROPEA DE NEUTRONES POR ESPALACION", "LUNDS UNIVERSITET", "MITTUNIVERSITETET", "PAUL SCHERRER INSTITUT", "SCIENCE AND TECHNOLOGY FACILITIES COUNCIL", "EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH", "DANMARKS TEKNISKE UNIVERSITET"], "EU_Contribution": ["EUR 19 941 964"], "Project_Title": ["Building a research infrastructure and synergies for highest scientific impact on ESS"], "Total_Cost": ["EUR 19 941 964"], "Country": ["Sweden", "Sweden", "Czech Republic", "Denmark", "Denmark", "France", "France", "Germany", "Hungary", "Italy", "Italy", "Netherlands", "Spain", "Sweden", "Sweden", "Switzerland", "United Kingdom", "Switzerland", "Denmark"], "Project_ACR": ["BrightnESS"], "Technology_Description": "The science of materials has always been at the centre of scientific and technological progress in human development. The tools to understand materials that fashion them to meet our societal needs have been just as important. Thermal neutrons are one of the most powerful probes that look directly at the structure and dynamics of materials from the macro- to the microscopic scale and from nano-seconds to seconds. It is therefore natural that a group of 17 European Partner Countries have joined together to construct the world\u2019s most powerful neutron source, the European Spallation Source (ESS). The importance of ESS has been recognised by ESFRI who have prioritised it as one of three Research Infrastructures (RIs) for this INFRADEV-3 call. However, simply constructing the most powerful spallation neutron source will not, by itself, ensure the maximum scientific or technological impact. What is needed is an integrated program that ensures that key challenges are met in order to build an ESS that can deliver high impact scientific and technological knowledge. With a timeline of 36 months, involving 18 Consortium Partners and a budget of \u20ac 19.941.964, the BrightnESS proposal will ensure that (A) the extensive knowledge and skills of European companies, and institutes, are best deployed in the form of In-Kind Contributions to ESS for its construction and operation, (B) that technology transfer both to, and from, the ESS to European institutions and companies is optimised and, (C) that the maximum technical performance is obtained from the ESS target, moderators and detectors in order to deliver world class science and insights for materials technology and innovation.", "To": ["2018-08-31, ongoing project |"], "Meta": [""], "Topic_s": ["INFRADEV-3-2015 - Individual implementation and operation of ESFRI projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Sweden"], "Activity": ["Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Jiri Matas", "Tel.: +420 22435721", "Fax: +420 224357385", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["676548"], "Call_for_Proposal": ["H2020-INFRADEV-1-2015-1"]}, -{"Partners": ["THE UNIVERSITY OF SUSSEX"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Faking It: The production, perception, and function of social voice modulation"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["Voice Modulation"], "Technology_Description": "The human voice is a social tool. Non-linguistic voice cues can influence judgements of attractiveness, formidability, trustworthiness, intelligence, and general likeability, with meaningfully differential social outcomes depending on whether ones voice is credited, unduly or not, with positive or negative attributes. Yet, despite its apparent societal implications and the known capacity for vocal control, studies of human voice perception have focused on static rather than dynamic speech. The proposed project will explore the vastly understudied niche of human voice modulation. The Research Objectives of the project are to: (1) Provide the first experimental evidence of voice modulation in four novel social contexts (political debate, commercial ad, public lecture, and first date); (2) Describe the structure and production mechanisms of modulated speech using new technology developed through a secondment; (3) Identify individual and environmental factors that affect the use and nature of modulated speech; (4) Test the extent to which voice modulation effectively influences social attributions and decisions. The project will be the first to examine voice modulation across cultures, addressing a serious need for comparative research in psychology, and facilitating international collaboration. The research objectives will be achieved through a unique combination of lab and field voice recordings, spectrotemporal speech analysis, questionnaire data, cross-cultural and cross-linguistic playback experiments, and sophisticated statistical modelling. This original line of research will provide ample insight into how the voice affects human behaviour, ultimately helping to uncover the functions and origins of nonverbal communication, but also educating lay and scientific communities about social stereotyping and its socioeconomic impact. Importantly, the Fellowship will put me in an excellent position to secure a research station in one of the top European universities.", "To": ["2018-01-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-02-01"], "Project_ID": ["655859"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["NATIONAL UNIVERSITY OF IRELAND GALWAY"], "EU_Contribution": ["EUR 175 866"], "Project_Title": ["Genome surveillance by small non-coding RNAs"], "Total_Cost": ["EUR 175 866"], "Country": ["Ireland"], "Project_ACR": ["GSR"], "Technology_Description": "Water, oxygen, and sunlight are essential to most forms of life, yet they also represent a challenging environment for the genetic material as they drive reactions that lead to damage of DNA. To ensure cell survival, an elaborate response to DNA damage maintains genome integrity. Until recently, the DNA damage response (DDR) was described as a wave of protein posttranslational modifications that signal the presence of DNA damage to the cell and mobilize enzymatic repair pathways. Recently, genome-wide screens and advances in next-generation sequencing (NGS) shed light on the role of RNA-binding proteins and non-coding RNAs (ncRNAs) in the DDR. A novel class of small ncRNAs produced from the vicinity of DNA double strand breaks (DSB) \u2013 DNA damage-inducible ncRNAs (diRNAs) - were identified in plants, flies, and mammals. Our understanding of the biogenesis of diRNAs and their role in DSB repair is currently limited by the lack of methods for their detection that can be implemented in every laboratory. The aim of this project is to close this technological gap by developing robust and versatile methods of analysis of diRNA biogenesis. Our original approach consists to map diRNAs using NGS technology at site-specific DSBs inducible by an endonuclease, and to create the first database of human diRNAs. The knowledge of the sequences of diRNAs will allow us to develop methods for detection of both precursor and mature diRNAs. To identify novel players of the diRNA biogenesis pathway, we will perform a small-scale siRNA-based screen of RNA-binding proteins using the developed methods. This study will lead to important technological and knowledge-based developments in the DDR field, and to a better understanding of how the \u201cnon-coding\u201d genome regulates important cellular functions.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["706828"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITAET ZU KOELN"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Characterising plant interactions with bacteria that promote the uptake of nitrogen and sulphur from organic sources"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["PINBAC"], "Technology_Description": "The plant rhizosphere contains an abundant and diverse array of microbes, and plants interact with this microbial community in diverse ways, from mutualistic to neutral to pathogenic. It is proposed that future agricultural systems should strategically incorporate mutualistic plant-microbe associations, whereby high-performing combinations of plant genotypes and microbial populations are co-cultivated to promote improved nutrient use efficiency and decreased fertiliser application. Currently, there is a poor scientific understanding of the precise biochemical transformations and exchanges that occur in mutualistic associations between plants and microbes, and it is also unclear which specific microbial species are the most effective for supporting plant growth and nutrition. There is evidence that plant genotypes exhibit differing capacities to shape their rhizospheric microbiome , but our poor mechanistic understanding of this phenomenon prevents breeding strategies to select crop varieties that will host favourable microbial interactions. Therefore, this project proposes to address these gaps in scientific knowledge, by undertaking co-cultivation experiments that investigate which specific bacterial species are most effective for enhancing plant uptake of nitrogen (N) and sulphur (S) from organic sources, as well as which specific Arabidopsis accessions are the most receptive hosts for these interactions. Next, isotope labelling and metabolic flux studies will be undertaken in the best and worst performing plant-microbe combinations, to define the specific biochemical routes of N & S transfer that are favourable for plant nutrition. Also, genetic investigations will be undertaken to find the key genes responsible for favourable plant-microbe interactions. This project combines the complementary expertise of its participants to deliver high-quality training to the researcher, which will enhance his professional maturity in this strategically important field.", "To": ["2018-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-07-01"], "Project_ID": ["705808"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITE DE PARIS-SORBONNE (PARIS IV)"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["The dawn of writing in Western Mediterranean: a comparative approach to the Iberian epigraphic corpus"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["ZEPHYROS"], "Technology_Description": "This project proposes a study of all known Iberian inscriptions (about 2.000 documents dating from the 5th century BC to the 1st century AD) in a comparative and interdisciplinary perspective. The study of the Iberian corpus will be set in a broad cultural context, including the rise of the first Western written traditions and their linguistic and cultural contacts. I will focus on issues such as the relationship between text and object, the Iberian adoption of exogenous epigraphic models (mainly Phoenician/Punic, Greek and Latin), and the level of literacy within the male and female spheres of this society.", "To": ["2017-09-14, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-15"], "Project_ID": ["655938"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITE DE PARIS-SORBONNE (PARIS IV)"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Literature against anti-Semitism (1940-1944). French and Soviet emigr\u00e9 writers in France against the persecution of the Jews"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["LIAGAN"], "Technology_Description": "The research project Literature against anti-Semitisme (1940-1944). French and Soviet emigr\u00e9 writers in France against the persecution of the Jews aims at investigating the views which writers had of the persecution of the Jews in Occupied France. More exactly, it aims at approaching the texts of the writers who reacted to the injustices suffered by the Jews who became exiles and were hunted down as Others, before being simply eliminated. In this context, we intend to study various works of fiction (stories, novels, poetry) in which the question of the persecution of the Jews is at stake. The project is defined by two axes: (1) the French writers who raised their voices against the persecutions of which the Jews were victims in France, (2) \u00e9migr\u00e9 writers from Central and Oriental Europe (Russian, Russian-language, Georgian) who lived in France during the Occupation and who also stood up against these injustices. ", "To": ["2017-05-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-06-01"], "Project_ID": ["652978"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITE DE PARIS-SORBONNE (PARIS IV)"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Ancient Egypt\u2019s Wine Rebirth"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["EGYWINE"], "Technology_Description": "The present paradigm on wine history states that viticulture is originated in the Near East and that Europe\u2019s wine culture is a Greek and Roman heritage. The Egyptian wine culture is one of the world\u2019s most ancients, however, the extensive archaeological evidences have not been fully investigated.", "To": ["2018-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["699858"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITY OF CENTRAL LANCASHIRE"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["MILK BANKING AND THE UNCERTAIN INTERACTION BETWEEN MATERNAL MILK AND ETHANOL"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["MUIMME"], "Technology_Description": "Donor human milk banks are expanding around the world at an exponential rate, which is directly linked to global increases in premature births. The importance of human milk for prematurely born infants has been extensively identified, even among the recent social scientific work that has questioned the efficacy of human milk and health considerations. In addition, research also shows that a significant percentage of these mothers, at least initially, experience lactation problems. Europe is taking a leadership role in expansion of human milk banks, although issues associated with alcohol consumption and maternal donations are a concern for clinicians and health care staff, given the increasing problems associated with drinking among women of childbearing age. Europe with the highest alcohol per capita consumption rates in the world, makes these issues particularly immediate. The United Kingdom (UK) with its long history and current global leadership role is an ideal place to study these considerations which will inform these larger issues of human milk for the prematurely born infant. A leader in this century old intervention, supporting not only one of the oldest hospital based banks in Europe, but also an important cross-border collaborations on the island of Ireland, along with a research based national bank in Scotland, each representing different cases contributing significantly to the re-birth of the medical control of human milk. The UK is poised to offer the world vital information regarding donor human milk banking, maternal bodies and \u2018trust\u2019, an important sociological social theoretical concept which will be used to frame the triangulated data collected for this project (including interviews, archival data, and ethnographic information). Supporting an excellent experienced female researcher to return to the academy following a maternity/career break, this project directly supports women and science in society. MUIMME is an old Irish word for wet-nurse.", "To": ["2017-03-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-04-01"], "Project_ID": ["654495"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITETET I OSLO"], "EU_Contribution": ["EUR 208 400,40"], "Project_Title": ["Unraveling the ecology of a widespread fungal group by genomic, isotopic and physiological analyses"], "Total_Cost": ["EUR 208 400,40"], "Country": ["Norway"], "Project_ACR": ["Mycena"], "Technology_Description": "This proposal aims to shed light on the life strategy of Mycena (or bonnet mushrooms), a widespread group of macrofungi and with important functions in forests and other terrestrial ecosystems. While its members have traditionally been uniformly assumed to be degraders of litter, wood and other dead biological matter, very recent research has suggested that several members could in fact be parasitically or mutualistically biotrophic with plants. In numerous studies, environmental sequences with affinity to Mycena have been observed associated with plant roots. To solve this puzzle, we will use a multifaceted, interdisciplinary approach where we combine traditional knowledge about fungal cultivation with advanced DNA sequencing technology and isotope analyses techniques. The rapidly developing high throughput DNA sequencing technology (HTS) produces millions of DNA strands within hours, and by applying this to plant roots, we will quickly obtain an overview of the presence of Mycena in or on plant roots (indicating a possible biotrophic relationship). We will create a database of Mycena sequences from our own sequencing as well as sequences already publicly available. By sequencing the entire genome of five carefully selected species of Mycena, we will be able to analyse the genomic content associated with different life strategies. As molecular identification of Mycena associated with plant roots does not indicate an ecological interaction per se, we will employ innovative research techniques designed to quantify potential interactions. Isotopic fractionation of carbon/nitrogen of Mycenas and plants at field sites can reveal the mushroom\u00b4s source of carbon, and co-culturing of biotrophic Mycenas together with plants will provide direct evidence for the nature of their relationship(s). This research will clarify the ecology of a prominent and widespread genus of fungi, thereby illuminating its role in forest and general plant ecology.", "To": ["2017-07-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-08-01"], "Project_ID": ["658849"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["NATIONAL UNIVERSITY OF IRELAND GALWAY"], "EU_Contribution": ["EUR 187 866"], "Project_Title": ["Real-time diagnostics for Enabling Advanced laser-based roll to roll materials Processing"], "Total_Cost": ["EUR 187 866"], "Country": ["Ireland"], "Project_ACR": ["REAP"], "Technology_Description": "An experienced researcher with laboratory expertise in real time monitoring of laser-matter-ambient-interactions will be diversified towards scalable production which is desperately needed to fully realise the potential of high repetition rate, multi-kiloWatt, femtosecond and picoseconds laser technologies. The fabrication of integrated multifunctional thin film devices by additive (inkjet, spray) and subtractive (laser) manufacturing on Roll to Roll (R2R) production platforms is also suddenly possible and desperately needed to transform the competitiveness of Europe\u2019s SME manufacturing sector. The training programme will lead to scalable innovation by developing diagnostics for ultra-precision laser processes. The initial objective of the project is to identify which intersecting value chains for real time or in-line diagnostics can fully realise the potential of short pulse laser structuring. Three diagnostics based on gated (i) spectral analysis of laser generated plasma plumes, (ii) image analysis of laser material ambient interactions and (iii) laser induced breakdown spectroscopy will be developed. The Fellow will demonstrate two process diagnostics using the R2R pilot line at the industry site. The application of these on-line tools will create pathways for cost effective production based on new nano-inspired materials relevant to flexible large area electronics. The multi-partner training environment provides excellent facilities for the talented ambitious Fellow. Over 30+ researchers will be directly impacted by the project. An active programme of knowledge transfer and information dissemination is also proposed based on industrial workshop, active conference participation, journal publications, and science promotion.", "To": ["2017-06-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-07-01"], "Project_ID": ["659454"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITETET I OSLO"], "EU_Contribution": ["EUR 196 400,40"], "Project_Title": ["Hybrid Particle-Field Approach Including Electrostatics for Large-Scale Simulations of Biological Systems"], "Total_Cost": ["EUR 196 400,40"], "Country": ["Norway"], "Project_ACR": ["HYPERBIO"], "Technology_Description": "Despite the continuous progress in computer simulations, the typical time and size bottlenecks are nowadays still heavily affecting the feasibility of large-scale simulations of complex biological systems at the molecular resolution accuracy. The current proposal aims at formulating a new hybrid particle-field approach including explicit treatment of electrostatic interactions for computational modelling of complex biological environments. The proposed method will combine the computational advantages of a self-consistent field approach (linear scaling cost for computation of intermolecular interactions, easy parallelization), becoming increasingly popular in polymer and soft-matter simulations, with a rigorous treatment of particles and explicit electrostatics. The proposed approach will allow fast and reliable simulations of polyelectrolyte mixtures, including biological charged membranes, multi-phase systems, and biological polymers (polysaccharides, proteins, nucleic acids etc), and it will make it possible to break by orders of magnitude the current limits for biomolecular simulations both in time and size. The project will have a main development part, where the self-consistent field formalism with electrostatics will be derived and implemented, and an applicative part, where the new methodology will be tested on lipopolysaccharide moieties. These large amphiphilic and chemically complex molecules constitute the outer membrane of Gram- bacteria, and are to date one of the major research targets to in antibiotic resistance studies. This project is multidisciplinary and involves international collaboration. This project would have a great positive impact on the applicant\u2019s early stage researcher career, identifying her as one of the key players in the opening a new pathway into molecular simulations of biological systems.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["704491"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["NATIONAL UNIVERSITY OF IRELAND GALWAY", "NATIONAL UNIVERSITY OF IRELAND GALWAY"], "EU_Contribution": ["EUR 1 477 622"], "Project_Title": ["Immune Response and Social Cognition in Schizophrenia"], "Total_Cost": ["EUR 1 477 622"], "Country": ["Ireland", "Ireland"], "Project_ACR": ["iRELaTE"], "Technology_Description": "Schizophrenia, affecting 0.5-1% of the population, is ranked by the World Health Organisation as more disabling than paraplegia or blindness in 18-34 year olds. Current treatments, developed over 50 years ago, are only partly effective in treating this disability, and new treatments are lacking. To address this treatment impasse, this project aims to develop and test a novel immune based model of deficits in social cognition \u2013 the set of mental operations that underlie social interactions (e.g. emotion recognition, theory of mind) and strongly predict social disability in schizophrenia. Based on recent discoveries in schizophrenia genetics, this project asks: (1) are genetic causes of deficits in social cognition mediated by effects on immune function during development and (2) does early social environment moderate these effects? To address these questions, the project has two parts. Part A focuses on neuropsychological and neuroimaging studies of social cognition in patients and healthy adults so as to (1) provide an innovative characterisation of the effects of inflammatory markers (e.g. pro-/anti- inflammatory cytokines) on social cognition, (2) establish whether these markers mediate the effects of recently identified genetic risk loci on schizophrenia, and (3) identify to what extent early social environment (e.g. parental relationships, childhood trauma) moderates this relationship. Part B focuses on behavioural and pharmacological studies in mice to (1) establish the causal effects of early immune challenge and early social environment on social cognition, and (2) test the translational benefits of anti-inflammatory treatment to normalize the resulting deficits. By validating an immune based model of schizophrenia, this project has the potential to move beyond current (dopamine based) treatments, and suggest groundbreaking alternatives for understanding and treating social disability in this and other neurodevelopmental disorders.", "To": ["2021-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-07-01"], "Project_ID": ["677467"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["THE UNIVERSITY OF SUSSEX"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Plant resilience and floral adaptation to pollinator change during a range expansion"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["FLORADAPT"], "Technology_Description": "Interactions among plants and floral visitors determine the outcome of many important processes, such as pollination, plant reproductive success and, in the longer term, plant evolution. Recent evidence shows human-induced pollinator declines and in consequence plants are experiencing new \u201cpollinator environments\u201d. These changes can be detrimental to plant populations, or alternatively, they could be resilient by adapting to the new environments. This project will use a multidisciplinary combination of field studies and genome sequencing to investigate the resilience and potential for evolutionary change of plant populations when faced with changes in pollinators. For this I will use the recent large-scale range expansion of a European insect-pollinated herb, Digitalis purpurea, as a natural experiment to compare pollinators, floral traits, and estimates of heritability in native versus naturalised populations in the New World. The naturalised populations are pollinated by different animals, and could harbour lower genetic variation. Dense molecular marker panels will be used to estimate heritability in the field. The results will provide important insight into 1) the evolution of plant traits in conditions that could favour innovative change, and 2) the consequences of human-induced environmental changes on plant and pollinator populations in the long term. The main novelty is the combination of the study of changed natural selection regimes with the estimation of trait heritability in the same wild populations. This project will increase my competitiveness for academic consolidation through training a critical period in my career. Working at the University of Sussex will provide excellent training in insect evolution and conservation, bioinformatics, and teaching and mentoring students in a top-class research environment. In turn, I will contribute my knowledge on plant biology through teaching and collaborations in a mostly animal-oriented group.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["706365"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["NATIONAL UNIVERSITY OF IRELAND GALWAY", "NATIONAL UNIVERSITY OF IRELAND GALWAY"], "EU_Contribution": ["EUR 1 499 329"], "Project_Title": ["Frontier Research on the Dielectric Properties of Biological Tissue"], "Total_Cost": ["EUR 1 499 329"], "Country": ["Ireland", "Ireland"], "Project_ACR": ["BIOELECPRO"], "Technology_Description": "The dielectric properties of biological tissues are of fundamental importance to the understanding of the interaction of electromagnetic fields with the human body. These properties are used to determine the safety of electronic devices, and in the design, development and refinement of electromagnetic medical imaging and therapeutic devices. Many historical studies have aimed to establish the dielectric properties of a broad range of tissues. A growing number of recent studies have sought to more accurately estimate these dielectric properties by standardising measurement procedures, and in some cases, measuring the dielectric properties in-vivo. However, these studies have often produced results in direct conflict with historical studies, casting doubt on the accuracy of the currently utilised dielectric properties. At best, this uncertainty could significantly delay the development of electromagnetic imaging or therapeutic medical devices. At worst, the health dangers of electromagnetic radiation could be under-estimated. The applicant will embark upon frontier research to develop improved methods and standards for the measurement of the dielectric properties of biological tissue. The research programme will accelerate the design and development of electromagnetic imaging and therapeutic devices, at a time when the technology is gaining significant momentum. The primary objective of the research is to develop a deep understanding of the fundamental factors which contribute to errors in dielectric property measurement. These factors will include in-vivo/ex-vivo measurements and dielectric measurement method used, amongst many others. Secondly, a new open-access repository of dielectric measurements will be created based on a greatly enhanced understanding of the mechanisms underlying dielectric property measurement. Finally, new electromagnetic-based imaging and therapeutic medical devices will be investigated, based on the solid foundation of dielectric data.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["637780"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["UNIVERSITETET I OSLO", "UNIVERSITETET I OSLO"], "EU_Contribution": ["EUR 1 499 439"], "Project_Title": ["Effects of Medication Use in Pregnancy on Infant Neurodevelopment"], "Total_Cost": ["EUR 1 499 439"], "Country": ["Norway", "Norway"], "Project_ACR": ["DrugsInPregnancy"], "Technology_Description": "Currently, thousands of pregnant women in the EU and worldwide are being increasingly prescribed medications for which we do not have sufficient information on fetal safety. I hypothesize that our current understanding of safety pharmacology is oversimplified and that medication prescribed during pregnancy may play an unrecognized role in the development of neurodevelopmental disorders.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["639377"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["THE UNIVERSITY OF SUSSEX", "THE UNIVERSITY OF SUSSEX"], "EU_Contribution": ["EUR 1 494 865"], "Project_Title": ["Sensory Experiences for Interactive Technologies"], "Total_Cost": ["EUR 1 494 865"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["SenseX"], "Technology_Description": "The senses we call upon to interact with technology are still very limited relying mostly on visual and auditory senses. The grand challenge and vision of this project is to gain a rich and integrated understanding on touch, taste, and smell experiences for interactive technologies.", "To": ["2020-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-04-01"], "Project_ID": ["638605"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["UNIVERSITAET ZU KOELN", "UNIVERSITAET ZU KOELN"], "EU_Contribution": ["EUR 1 928 750"], "Project_Title": ["Many-body physics and superconductivity in 2D materials"], "Total_Cost": ["EUR 1 928 750"], "Country": ["Germany", "Germany"], "Project_ACR": ["SUPER-2D"], "Technology_Description": "The goal of this project is to prepare and functionalize layered materials and then to characterize them in-situ using a novel combination of electrical transport, photoelectron and optical spectroscopy. This approach provides a solution to the intense research efforts in trying to engineer, probe and unravel many-body physics and the superconducting coupling mechanism in layered solids. The materials under investigation are based on the families of graphene, dichalcogenides and iron based superconductors. Chemical functionalization using dopants and strain allows for an unprecedented control over their physical properties. The proposed material systems provide a new arena to explore diverse condensed matter phenomena such as electron correlation, electron-phonon coupling and superconductivity. The groundbreaking aspects of this proposal are as follows: (1) development of a unique setup where electrical transport, angle-resolved photoemission (ARPES) and optical spectroscopy is measured in-situ on the same sample, (2) large-area deterministic layer-by-layer growth by chemical vapour deposition (CVD) and molecular beam epitaxy, (3) the effects of mechanical strain and hence large pseudomagnetic fields on the electronic band structure will be investigated using ARPES, (4) the effects of alkali metal doping on the superconducting transition temperature and the spectral function will be investigated using transport, ARPES and optical spectroscopies shining light onto the superconducting pairing mechanisms in different classes of materials. The proposal's feasibility is firmly grounded on the pioneering work of the PI\u2019s group on superconducting coupling in functionalized graphene and the in-situ ARPES measurements of a CVD grown graphene/BN heterostructure.", "To": ["2020-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-06-01"], "Project_ID": ["648589"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["THE UNIVERSITY OF SUSSEX", "THE UNIVERSITY OF SUSSEX", "THE UNIVERSITY OF LIVERPOOL"], "EU_Contribution": ["EUR 1 000 565"], "Project_Title": ["Sexual Orientation and Gender Identity Claims of Asylum: A European human rights challenge"], "Total_Cost": ["EUR 1 000 565"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom"], "Project_ACR": ["SOGICA"], "Technology_Description": "This project will generate the first ever theoretically and empirically-grounded comparative and comprehensive picture of the status and legal experiences of asylum-seekers across Europe claiming international protection on the basis of their sexual orientation or gender identity (SOGI), and determine how the European asylum systems can treat more fairly asylum claims based on the claimant\u2019s SOGI. Every year, thousands of individuals claim asylum in Europe based on their SOGI, and more often than not their claims are treated unfairly, especially considering the disproportionately high rate of refusals on these grounds. There have been very limited attempts to address this issue, and this research will overcome this gap by carrying out a study more comprehensive than any other done in this field in the past, and producing outcomes that are unparalleled in terms of their reach. ", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["677693"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["NATIONAL UNIVERSITY OF IRELAND GALWAY", "NATIONAL UNIVERSITY OF IRELAND GALWAY"], "EU_Contribution": ["EUR 1 499 431"], "Project_Title": ["Clarifying Optimal Sodium Intake Project"], "Total_Cost": ["EUR 1 499 431"], "Country": ["Ireland", "Ireland"], "Project_ACR": ["COSIP"], "Technology_Description": "Hypertension is a leading risk factor for cardiovascular disease (CVD) globally, accounting for 25-35% of the population-attributable fraction. Sodium (salt) intake is a key determinant of blood pressure, and reducing sodium intake has emerged as an important target for population-based interventions to prevent CVD. However, there is considerable uncertainty about the optimal level of sodium (salt) intake that is associated with lowest CVD risk, and whether optimal levels differ for different populations and individuals. In this proposal, we will answer key fundamental research questions about the association of sodium intake with blood pressure and CVD risk. Our research challenges current guideline recommendations of low-sodium intake for all populations. Specifically, we will: a) determine whether sustained (long-term) low sodium intake is associated with beneficial (or adverse) effects on established and novel CV biomarkers; b) explore whether inter-daily \u2018pattern\u2019 of sodium intake is an important determinant of 24-hour blood pressure pattern; c) determine whether the association between sodium intake and CVD varies by ethnicity, sex, age, other dietary factors (e.g. potassium intake), or other factors in 2 large international epidemiologic studies (PURE and INTERSTROKE; n>125,000 individuals); d) quantify the population-attributable fraction of excess sodium intake on global burden of CVD (stroke, myocardial infarction, heart failure and CV death), and model the potential impact of various population-based approaches to reducing sodium intake; e) determine whether sodium intake is associated with other vascular-related clinical conditions, namely including atrial fibrillation, cognitive impairment and falls (providing novel information); f) determine whether genetic variants associated with \u2018salt sensitivity\u2019 and hypertension are association with blood pressure and stroke, and whether these associations are modified by sodium intake.", "To": ["2020-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-05-01"], "Project_ID": ["640580"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["UNIVERSITAET ZU KOELN", "UNIVERSITAET ZU KOELN"], "EU_Contribution": ["EUR 1 488 048"], "Project_Title": ["The radiative interstellar medium"], "Total_Cost": ["EUR 1 488 048"], "Country": ["Germany", "Germany"], "Project_ACR": ["RadFeedback"], "Technology_Description": "The pressure, radiation, and ionization from the warm (UV emitting) and hot (X-ray emitting) gas has a significant impact on the cold, star-forming interstellar medium. We propose to carry out a comprehensive 3D study of the turbulent, multi-phase ISM in different environments that includes, for the first time, a proper treatment of UV and X-ray emission from stellar (primary) sources and extended (secondary) sources like cooling shock fronts and evaporating clouds. We do this by means of massively parallel, high-resolution 3D simulations that capture the complex interplay of gravity, magnetic fields, feedback from massive stars (ionizing radiation, radiation pressure, stellar winds, supernovae), heating and cooling including X-rays and cosmic rays, and chemistry. We are developing a novel, original and highly efficient method to accurately treat the transfer of radiation from multiple point and extended sources in the 3D simulations. Radiation and chemistry will be coupled to achieve self-consistent heating, cooling, and ionization rates. Moreover, accurate synthetic observations covering the large dynamic range from X-rays down to radio emission will be generated to set the results in the proper observational context. This will enable us to address the key science questions: How efficient is stellar feedback in different environments and which feedback process is dominant? What is the precise role of UV radiation and X-rays, also from secondary sources? Are the observations following the key dynamical players? How do we best interpret ISM observations from ALMA, SKA, or ATHENA? How do we assist in designing future observations? With the resources requested here we will perform the most self-consistent theoretical study of the multi-phase ISM so far, thus building up a leading group for ISM research in Europe. To stimulate worldwide scientific activities and interactions we will make all data available to the community through an open-access web interface.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["679852"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["UNIVERSITETET I OSLO", "UNIVERSITETET I OSLO"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Controlling Cardiomyocyte Dyadic Structure"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Norway", "Norway"], "Project_ACR": ["CARDYADS"], "Technology_Description": "Contraction and relaxation of cardiac myocytes, and thus the whole heart, are critically dependent on dyads. These functional junctions between t-tubules, which are invaginations of the surface membrane, and the sarcoplasmic reticulum allow efficient control of calcium release into the cytosol, and also its removal. Dyads are formed gradually during development and break down during disease. However, the precise nature of dyadic structure is unclear, even in healthy adult cardiac myocytes, as are the triggers and consequences of altering dyadic integrity. In this proposal, my group will investigate the precise 3-dimensional arrangement of dyads and their proteins during development, adulthood, and heart failure by employing CLEM imaging (PALM and EM tomography). This will be accomplished by developing transgenic mice with fluorescent labels on four dyadic proteins (L-type calcium channel, ryanodine receptor, sodium-calcium exchanger, SERCA), and by imaging tissue from explanted normal and failing human hearts. The signals responsible for controlling dyadic formation, maintenance, and disruption will be determined by performing high-throughput sequencing to identify novel genes involved with these processes in several established model systems. Particular focus will be given to investigating left ventricular wall stress and stretch-dependent gene regulation as controllers of dyadic integrity. Candidate genes will be manipulated in cell models and transgenic animals to promote dyadic formation and maintenance, and reverse dyadic disruption in heart failure. The consequences of dyadic structure for function will be tested experimentally and with mathematical modeling to examine effects on cardiac myocyte calcium homeostasis and whole-heart function. The results of this project are anticipated to yield unprecedented insight into dyadic structure, regulation, and function, and to identify novel therapeutic targets for heart disease patients.", "To": ["2020-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-07-01"], "Project_ID": ["647714"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["UNIVERSITETET I OSLO", "UNIVERSITETET I OSLO"], "EU_Contribution": ["EUR 1 995 963,75"], "Project_Title": ["ALMA \u2013 The key to the Sun\u2019s coronal heating problem."], "Total_Cost": ["EUR 1 995 963,75"], "Country": ["Norway", "Norway"], "Project_ACR": ["SolarALMA"], "Technology_Description": "How are the outer layers of the Sun heated to temperatures in excess of a million kelvin? A large number of heating mechanisms have been proposed to explain this so-called coronal heating problem, one of the fundamental questions in contemporary solar physics. It is clear that the required energy is transported from the solar interior through the chromosphere into the outer layers but it remains open by which physical mechanisms and how the provided energy is eventually dissipated. The key to solving the chromospheric/coronal heating problem lies in accurate observations at high spatial, temporal and spectral resolution, facilitating the identification of the mechanisms responsible for the transport and dissipation of energy. This has so far been impeded by the small number of accessible diagnostics and the challenges with their interpretation. The interferometric Atacama Large Millimeter/submillimeter Array (ALMA) now offers impressive capabilities. Due to the properties of the solar radiation at millimeter wavelengths, ALMA serves as a linear thermometer, mapping narrow layers at different heights. It can measure the thermal structure and dynamics of the solar chromosphere and thus sources and sinks of atmospheric heating. Radio recombination and molecular lines (e.g., CO) potentially provide complementary kinetic and thermal diagnostics, while the polarisation of the continuum intensity and the Zeeman effect can be exploited for valuable chromospheric magnetic field measurements. ", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["682462"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["THE UNIVERSITY OF SUSSEX", "THE UNIVERSITY OF SUSSEX"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Zebrafish vision in its natural context: from natural scenes through retinal and central processing to behaviour."], "Total_Cost": ["EUR 1 500 000"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["NeuroVisEco"], "Technology_Description": "All visual systems are specialised to best serve an animal\u2019s sensory niche, yet how such specialisations are achieved through phylogenetic and developmental adaptations of the \u2018common vertebrate visual system blueprint\u2019 are poorly understood. I will study these adaptations in the visual system of zebrafish. I will use two-photon functional imaging and computational modelling to investigate how the visual system of zebrafish samples and processes behaviourally meaningful stimuli in the natural world. I will then use optogenetic manipulations while zebrafish navigate a virtual reality environment to directly probe the role of visual circuits in driving behaviour. Specifically, I will pursue four Aims:", "To": ["2021-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["677687"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["UNIVERSITETET I OSLO", "UNIVERSITETET I OSLO"], "EU_Contribution": ["EUR 1 443 472"], "Project_Title": ["Resonant Nuclear Gamma Decay and the Heavy-Element Nucleosynthesis"], "Total_Cost": ["EUR 1 443 472"], "Country": ["Norway", "Norway"], "Project_ACR": ["gRESONANT"], "Technology_Description": "THE GRAND CHALLENGE: The \u201cHoly Grail\u201d of nuclear astrophysics is to understand the astrophysical processes responsible for the formation of the elements. A particularly challenging part is the description of the heavy-element nucleosynthesis. The only way to build the majority of these heavy nuclides is via neutron-capture processes. Unaccounted-for nuclear structure effects may drastically change these rates. ", "To": ["2020-02-29, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-03-01"], "Project_ID": ["637686"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["UNIVERSITETET I OSLO", "UNIVERSITETET I OSLO"], "EU_Contribution": ["EUR 1 350 000"], "Project_Title": ["The role of 5HT3a inhibitory interneurons in sensory processing"], "Total_Cost": ["EUR 1 350 000"], "Country": ["Norway", "Norway"], "Project_ACR": ["SurfaceInhibition"], "Technology_Description": "How do cortical circuits process sensory stimuli that leads to perception? Sensory input is encoded by complex interactions between principal excitatory neurons and a diverse population of inhibitory cells. Distinct inhibitory neurons control different subcellular domains of target principal neurons, suggesting specific roles of different cells during sensory processing. However, the individual contribution of these inhibitory subtypes to sensory processing remains poorly understood. This is mainly due to the technical challenges of recording the activity of identified cell types in-vivo, in response to quantified sensory stimuli. Therefore, I propose a novel approach based on four pillars: 1) An optically accessible circuit in the superficial layers of the cortex, comprised of inhibitory cells expressing the serotonin receptor 5HT3a, and the distal dendrites of pyramidal neurons. 2) A novel combination of electrophysiology and 3D two-photon imaging to simultaneously record the activity of morphologically identified 5HT3a cells and their dendritic targets. 3) A head-fixed perceptual decision task, whereby mice use their whiskers to determine the location of an object, allowing an accurate description of the sensory stimulus. 4) The integration of experimental data and computer models to gain mechanistic insights into circuit functions. The 5HT3a cells and the distal dendrites of pyramidal neurons receive \u2018top-down\u2019 contextual information from other cortical areas that is essential for constructing meaningful perceptions of sensory stimuli. Thus I hypothesize that 5HT3a cells influence sensory perceptions by controlling the excitability of the pyramidal cell distal dendrites that integrate top-down and sensory input. Thus, I will not only reveal novel functions of inhibitory neurons, I will also shed light on how top-down and sensory input is integrated, and I will provide novel methods to test the functions of other cell types in normal mice and disease models.", "To": ["2020-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-12-01"], "Project_ID": ["639272"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["ALFRED-WEGENER-INSTITUT HELMHOLTZ-ZENTRUM FUR POLAR- UND MEERESFORSCHUNG"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["ARCGATE: maximizing the potential of Arctic Ocean Gateway array"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["ARCGATE"], "Technology_Description": "Predictions that the Arctic Ocean might be ice-free by the middle of the 21st century are of major social, economic, political and scientific interest. Making sensible decisions on European Arctic economic development requires that scientific knowledge and data are more accessible and usable by both academics and non-academics alike. ARCGATE aims to obtain innovative physical and biogeochemical budgets for the Arctic Ocean based on the Arctic gateway observations. Integrating Arctic gateway observations the applicant has recently developed an innovative method to obtain quasi-synoptic and time varying comprehensive budget estimates using a box inverse model. The main objective of ARCGATE is to extend the inverse box model methodology to calculate multi-year Arctic heat and fresh water (FW) budget variations during 2004-2010, including import of heat, export of FW and storage of both. Over 20 million euro has already been spent on Arctic observations during this period. The host institute of this proposal holds about half of historical Arctic gateway observations. The obtained budget estimates will be disseminated and exploited through an open data policy. Furthermore, ARCGATE aims to push disciplinary and sectional boundaries. By applying the same pan-Arctic approach, the total alkalinity budget for summer 2005 will be calculated. A sound estimate of the total alkalinity budget will significantly advance understanding of the entire carbonate system of the Arctic Ocean. Mobility from UK to Germany is key to the success of ARCGATE enabling synthesis of the pan-Arctic inverse box-model developed in UK over the last six years with state-of-the-art estimates of Arctic Ocean heat, FW storage changes in time, and a new interpretation of total alkalinity all developed at the host institute for this project. Close links to the commercial Arctic shipping sector will be developed by disseminating the results of ARCGATE at international shipping conferences.", "To": ["2017-06-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations"], "From": ["2015-07-01"], "Project_ID": ["652757"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITAET ZU KOELN", "UNIVERSITAET ZU KOELN"], "EU_Contribution": ["EUR 1 676 423,75"], "Project_Title": ["Many-Body Physics with Driven Open Quantum Systems of Atoms, Light and Solids"], "Total_Cost": ["EUR 1 676 423,75"], "Country": ["Germany", "Germany"], "Project_ACR": ["DOQS"], "Technology_Description": "Understanding the quantum many-particle problem is one of the grand challenges of modern physics. While tremendous progresses have been made over the past decades in thermodynamic equilibrium, nonequilibrium many-body quantum physics is still in its infancy. Strong motivation for addressing this challenge comes from recent experimental developments in diverse areas, ranging from cold atomic gases over light-driven semiconductors to microcavity arrays. This moves systems into the focus, which are located on the interface of quantum optics, many-body physics and statistical mechanics. They share in common that coherent and driven-dissipative quantum dynamics occur on an equal footing, creating scenarios without immediate counterpart in traditional condensed matter systems. This project has the goal of pushing forward the understanding of such driven open quantum systems. To this end, we follow a combined approach structured around three key challenges. (i) We aim to identify novel macroscopic phenomena, which manifestly witness microscopic non-equilibrium conditions. This concerns non-thermal stationary states, where we will shape an understanding of non-equilibrium phase diagrams and the associated phase transitions, in particular constructing a notion of driven quantum criticality. But it also encompasses the identification of new universal regimes in open system time evolution. Finally, we will extend the concept of topological order to a broader non-equilibrium context, motivated by quantum information applications. (ii) We will create new theoretical tools, in particular advancing a flexible Keldysh dynamical quantum field theory for driven open quantum systems. (iii) We will address a broad spectrum of cutting edge experimental platforms in view of exploring our theoretical scenarios, and to foster mutual cross-fertilization. With an emphasis on cold atomic gases, this program also comprises exciton-polariton condensates and coupled circuit QED architectures.", "To": ["2021-01-31, ongoing project |"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-02-01"], "Project_ID": ["647434"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG", "RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG", "UNIVERSITETET I OSLO"], "EU_Contribution": ["EUR 1 413 750"], "Project_Title": ["How nature affects cooperation in common pool resource systems"], "Total_Cost": ["EUR 1 413 750"], "Country": ["Germany", "Germany", "Norway"], "Project_ACR": ["NATCOOP"], "Technology_Description": "The constraints and dynamics set by nature have a deep and significant impact on economic fundamentals and the ability to successfully manage renewable resources. This can be taken into account to formulate effective policies. However, the causal pathway from the natural to the social environment and its feedback for sustainable resource use is often overlooked, not the least because preferences and incentives are traditionally viewed as being stable and fixed. Yet, it is high time to take this new perspective: Social-ecological systems around the globe are under mounting stress and common pool resources are vital, in particular in developing countries. This project aims to establish how nature shapes preferences and incentives of economic agents and how this in turn affects common-pool resource management. To this end, I investigate three mechanisms: (A) how tipping points and thresholds in the natural system may encourage cooperation; (B) how the volatility of resource abundance influences risk preferences and how this in turn affects community-based management; and (C) how leadership, which is closely linked to risk preferences, interacts with the natural environment to foster cooperation that overcomes common-pool dilemmas. NATCOOP's bold agenda pushes the frontier of economics and sustainability science. Not only the investigation of the feedbacks between nature and cooperation from a new angle, also the scale and scope of the project -- combining cases from different socio-economic and ecological setting at three continents with theoretical and statistical work -- will generate new knowledge and be highly rewarding. Though challenging, I am confident that my background in economics and ecology puts me in an ideal position to achieve this important task. My ultimate goal is to identify circumstances in which natural preconditions and the social setting may go hand in hand to promote the sustainable use of renewable resources.", "To": ["2021-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-08-01"], "Project_ID": ["678049"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA", "UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA"], "EU_Contribution": ["EUR 1 672 103"], "Project_Title": ["Harmonic Analysis and Differential Equations: New Challenges"], "Total_Cost": ["EUR 1 672 103"], "Country": ["Spain", "Spain"], "Project_ACR": ["HADE"], "Technology_Description": "This project sets forth cutting-edge challenges in the field of Mathematical Physics that will be solved within a common framework by making novel use of classical tools of Harmonic Analysis such as Oscillatory Integrals and Trigonometric Sums, the Cauchy operator, and the so-called Carleman estimates. Three aspects will be covered:", "To": ["2020-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-12-01"], "Project_ID": ["669689"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["UNIVERSITAET ZU KOELN", "UNIVERSITAET ZU KOELN"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Mediation of stem cell identity and aging by proteostasis"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["StemProteostasis"], "Technology_Description": "By 2050, the global population over the age of 80 will triple. Thus, research for improving the quality of life at older age can be of enormous benefit for our ever-aging society. To address this challenge we propose an innovative approach based on a combination of stem cell research with genetic experiments in C. elegans. Mechanisms that promote protein homeostasis (proteostasis) slow down aging and decrease the incidence of age-related diseases. Since human embryonic stem cells (hESCs) replicate continuously in the absence of senescence, we hypothesize that they can provide a novel paradigm to study proteostasis and its demise in aging. We have found that hESCs exhibit increased proteasome activity. Moreover, we have uncovered that the proteasome subunit RPN-6 is required for this activity and sufficient to extend healtshpan in C. elegans. However, the mechanisms by which the proteasome regulates hESC function remain unknown. Our first aim is to define how the proteasome regulates not only hESC identity but also aging and the onset of age-related diseases. Moreover, one of the next challenges is to define how other proteostasis pathways impinge upon hESC function. We hypothesize that, in addition to the proteasome, hESCs differentially regulate other subcellular stress response pathways designed to protect them from disequilibrium in the folding and degradation of their proteome. We will perform a comprehensive study of proteostasis of hESCs and mimic this network in somatic cells to alleviate age-related diseases. Finally, we will determine whether loss of proteostasis promotes somatic stem cell (SC) exhaustion, which is one of the most obvious characteristics of the aging process and contributes to tissue degeneration. By using mouse models we will examine whether sustained proteostasis delays neural SC exhaustion. Our research will have an impact in several fields such as stem cell research, neurogenesis, proteostasis, aging and age-related diseases.", "To": ["2021-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-07-01"], "Project_ID": ["677427"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["UNIVERSITETET I OSLO", "UNIVERSITETET I OSLO"], "EU_Contribution": ["EUR 1 571 553,75"], "Project_Title": ["The Economics and Politics of Conservation"], "Total_Cost": ["EUR 1 571 553,75"], "Country": ["Norway", "Norway"], "Project_ACR": ["CONSERVATION"], "Technology_Description": "The UN\u2019s approach to climate policy is to focus on national emission caps for greenhouse gases. Most of the economic theory on environmental agreements is also studying such a demand-side approach, even though it is well known that such an approach has several flaws, including carbon leakage and the incentive to free ride. Recent theory has suggested that a better approach may be to focus on the supply-side of the equation, rather than the demand-side. While this recent theory is promising, it is only indicative and has several shortcomings that must be analysed. The goal of this project is to investigate in depth how to best use conservation as an environmental policy tool. The project aims at integrating the theory of emissions and pollution with a model of extraction and thus the supply of exhaustible resources in a coherent and dynamic game-theoretic framework. I will apply this framework to analyse negotiations, agreements, and contracts on extraction levels, and how such policies can interact, complement or substitute for agreements focusing on consumption/emissions. It will also be important to develop and apply the tools of political economics to investigate which (second-best) agreement one may expect to be feasible as equilibria of the game. For highly asymmetric settings, where the possessors of the resource are few (such as for tropical forests), side transfers are necessary and contract theory will be the natural analytical tool when searching for the best agreement. However, also standard contract theory needs to be developed further once one recognizes that the \u201cagent\u201d in the principal-agent relationship is an organization or a government, rather than an individual.", "To": ["2021-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-08-01"], "Project_ID": ["683031"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["HELMHOLTZ ZENTRUM POTSDAM DEUTSCHESGEOFORSCHUNGSZENTRUM GFZ", "UNIVERSITETET I OSLO", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "UNIVERSITA DEGLI STUDI ROMA TRE", "UNIVERSITY OF DURHAM", "UNIVERSITEIT UTRECHT", "THE UNIVERSITY OF EDINBURGH", "UNIVERSITE DE MONTPELLIER", "UNIVERSITE DE RENNES I"], "EU_Contribution": ["EUR 3 910 105,80"], "Project_Title": ["Understanding subduction zone topography through modelling of coupled shallow and deep processes"], "Total_Cost": ["EUR 3 910 105,80"], "Country": ["Germany", "Norway", "Switzerland", "Spain", "Italy", "United Kingdom", "Netherlands", "United Kingdom", "France", "France"], "Project_ACR": ["SUBITOP"], "Technology_Description": "The SUBITOP ETN is a framework for training and career development of young researchers in Geodynamics, Geophysics, Geology and Geomorphology. It has a scientific focus on the dynamics of continental margins where tectonic plates are recycled through subduction. Subduction processes have shaped and govern many aspects of the topography of Europe, and other continents, and they determine the patterns and intensity of geological hazards such as earthquakes, volcanic activity and landsliding. The Training Network will imbue 15 young scientists with the ability to address the links between the geological processes within subduction zones and the processes that impact the Earth\u2019s surface above, using a comprehensive range of modelling and observation techniques and exploiting the full diversity of active and ancient subduction systems within Europe.", "To": ["2020-02-29, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["674899"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["UNIVERSITAET ZU KOELN", "UNIVERSITAET ZU KOELN"], "EU_Contribution": ["EUR 2 499 735"], "Project_Title": ["The Making of the Earth \u2013 Reading the Geochemical Code from Meteorites and the Earth\u2019s Oldest Rocks"], "Total_Cost": ["EUR 2 499 735"], "Country": ["Germany", "Germany"], "Project_ACR": ["INFANT EARTH"], "Technology_Description": "It is still an open question how Earth became the rocky habitable planet as we know it today. This is because there is a significant time gap of several 100 million years between Earth\u2019s oldest rock archives (ca. 4 billion years old) and most extraterrestrial samples like meteorites that archive the birth of our solar system ca. 4.5 billion years ago. Within this time gap, three key processes that shaped our planet took place, i.e., Earth\u2019s growth via asteroidal collisions, formation of the metal core and a first solid crust, and the delivery of volatiles such as water. Because rock samples are lacking, these fundamental processes have to be traced indirectly, by using highly sophisticated geochemical tools like isotope or trace element compositions of younger rocks or meteorites. ", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["669666"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["NATIONAL UNIVERSITY OF IRELAND GALWAY", "INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE", "JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN", "RANDOX TEORANTA", "GOETEBORGS UNIVERSITET", "Fundaci\u00f3 Institut d'Investigaci\u00f3 Biom\u00e8dica de Bellvitge", "LUDWIG BOLTZMANN GESELLSCHAFT OSTERREICHISCHE VEREINIGUNG ZUR FORDERUNG DER WISSENSCHAFTLICHEN FORSCHUNG", "ROYAL COLLEGE OF SURGEONS IN IRELAND", "KATHOLIEKE UNIVERSITEIT LEUVEN", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "OPTIMATA LTD", "UNIVERSITAET STUTTGART"], "EU_Contribution": ["EUR 3 628 756,80"], "Project_Title": ["Endoplasmic Reticulum Stress in Health and Disease"], "Total_Cost": ["EUR 3 628 756,80"], "Country": ["Ireland", "France", "Germany", "Ireland", "Sweden", "Spain", "Austria", "Ireland", "Belgium", "United Kingdom", "Israel", "Germany"], "Project_ACR": ["TRAIN-ERS"], "Technology_Description": "Endoplasmic reticulum (ER) stress is emerging as a common feature in the pathology of numerous diseases including cancer, neurodegenerative disorders, metabolic syndromes and inflammatory diseases. Thus ER stress represents a potential therapeutic intervention point to be exploited to develop novel therapies, diagnostic tools and markers for these diseases. However, exploitation is hampered by the shortage of scientists with interdisciplinary training that can navigate with ease between the academic, industrial and clinical sectors, and that have the scientific and complementary skills, together with an innovative outlook, to convert research findings into commercial and clinical applications. This proposal will bring young researchers together with world-leading academics, clinicians and industry personnel, who are united in (1) their goal of forming a network of excellence aimed at understanding the ER stress response mechanistically and quantitatively and (2) applying this understanding to identify and validate the most suitable intervention points in order to provide innovative knowledge-driven strategies for the treatment of ER stress-associated diseases. ", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["675448"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["THE UNIVERSITY OF SUSSEX", "THE UNIVERSITY OF SUSSEX", "USTAV MOLEKULARNI GENETIKY AKADEMIE VED CESKE REPUBLIKY VEREJNA VYZKUMNA INSTITUCE"], "EU_Contribution": ["EUR 2 447 409"], "Project_Title": ["Defective DNA Damage Responses in Dominant Neurodegenerative Diseases"], "Total_Cost": ["EUR 2 447 409"], "Country": ["United Kingdom", "United Kingdom", "Czech Republic"], "Project_ACR": ["SIDSCA"], "Technology_Description": "DNA single-strand breaks (SSBs) are the most frequent DNA lesions arising in cells and are a major threat to cell survival and genome integrity, as indicated by the elevated genetic deletion, embryonic lethality, or neurological disease observed if single-strand break repair (SSBR) is attenuated. In particular, SSBR defects are associated with hereditary neurodegeneration in humans, as illustrated by the genetic diseases ataxia oculomotor apraxia-1 (AOA1), spinocerebellar ataxia with axonal neuropathy-1 (SCAN1), and microcephaly with early onset seizures (MCSZ). However, two major questions remain: what are the mechanisms by which SSBs trigger neurodegeneration, and to what extent do SSBs contribute to other genetic and/or sporadic neurodegenerative disease? Based on exciting new data we now propose that the impact of SSBs on neurodegeneration extends beyond rare SSBR-defective diseases to include more common motor neurone diseases (amyotrophic lateral sclerosis) and the genetically dominant spinocerebellar ataxias (SCAs). Ultimately, we suggest that SSBs might also be an etiological factor in normal human ageing. Finally, again based on new data, we propose that SSBs induce neurodegeneration by triggering over-activation of the SSB sensor protein, PARP1; thereby identifying inhibitors of this protein (currently licensed for cancer treatment) as a possible therapy for neurodegeneration. We will now address these hypotheses using a range of cutting edge molecular/cellular techniques. In particular we will (a), systematically examine all relevant amyotrophic lateral sclerosis/motor neurone disease (ALS/MND) and spinocerebellar ataxia (SCA) proteins for involvement in the DNA damage response, (b) Identify the mechanism/s by which ALS and SCA proteins engage in the DNA damage response, (c) Identify the role of ALS and SCA proteins in the DNA damage response, and (d) Explore PARP1 as a possible therapeutic target for treatment of neurodegenerative disease.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2016-10-01"], "Project_ID": ["694996"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE", "INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE", "INSTITUT MINES-TELECOM"], "EU_Contribution": ["EUR 1 492 252,50"], "Project_Title": ["Signal processing and Learning Applied to Brain data"], "Total_Cost": ["EUR 1 492 252,50"], "Country": ["France", "France", "France"], "Project_ACR": ["SLAB"], "Technology_Description": "Understanding how the brain works in healthy and pathological conditions is considered as one of the challenges for the 21st century. After the first electroencephalography (EEG) measurements in 1929, the 90\u2019s was the birth of modern functional brain imaging with the first functional MRI and full head magnetoencephalography (MEG) system. In the last twenty years, imaging has revolutionized clinical and cognitive neuroscience.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["676943"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["UNIVERSITETET I OSLO", "UNIVERSITETET I OSLO"], "EU_Contribution": ["EUR 2 900 000"], "Project_Title": ["Disequilibirum metamorphism of stressed lithosphere"], "Total_Cost": ["EUR 2 900 000"], "Country": ["Norway", "Norway"], "Project_ACR": ["DIME"], "Technology_Description": "Most changes in mineralogy, density, and rheology of the Earth\u2019s lithosphere take place by metamorphism, whereby rocks evolve through interactions between minerals and fluids. These changes are coupled with a large range of geodynamic processes and they have first order effects on the global geochemical cycles of a large number of elements.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["669972"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["THE UNIVERSITY OF SUSSEX", "THE UNIVERSITY OF SUSSEX", "ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE", "KOBENHAVNS UNIVERSITET", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 2 442 399,99"], "Project_Title": ["Trust, Global Traders, and Commodities in a Chinese International City"], "Total_Cost": ["EUR 2 442 399,99"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom", "Denmark", "United Kingdom"], "Project_ACR": ["TRODITIES"], "Technology_Description": "Trust, Global Traders, and Commodities in a Chinese International City", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["669132"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["NATIONAL UNIVERSITY OF IRELAND GALWAY", "UNIVERSIDADE DO MINHO", "THE ROYAL VETERINARY COLLEGE", "UNIVERSITEIT MAASTRICHT", "SOFRADIM PRODUCTION SASU", "TECHNOLOGIKO EKPEDEFTIKO IDRYMA IPIROU", "STEMCELL TECHNOLOGIES SARL", "PROXY BIOMEDICAL LIMITED", "STEMCELL TECHNOLOGIES UK LTD"], "EU_Contribution": ["EUR 3 876 965,64"], "Project_Title": ["Engineering in vitro microenvironments for translation of cell-based therapies for tendon repair"], "Total_Cost": ["EUR 3 876 965,65"], "Country": ["Ireland", "Portugal", "United Kingdom", "Netherlands", "France", "Greece", "France", "Ireland", "United Kingdom"], "Project_ACR": ["Tendon Therapy Train"], "Technology_Description": "Tendon Therapy Train is a research, training and innovation programme for human and equine tendon repair and regeneration that will exploit recent advancements in tissue engineering by self-assembly (TESA) technologies which have led to the clinical translation and commercialisation of advanced therapy medicinal products (ATMPs). Although TESA therapies have the potential to revolutionise healthcare for numerous clinical targets, a lack of researchers with the necessary interdisciplinary skillset to advance the field is limiting clinical translation. Tendon therapy train, a network of 8 beneficiaries and 8 partners (7 universities, 7 companies and 2 hospitals) from six countries across Europe, will train a cohort of 15 researchers to doctoral level in the interdisciplinary area of ATMPs. The innovative credentials of the research and training programme involve engineering suitable ex vivo culture environments that, by mimicking the native tendon tissue milieu (human and equine), will maintain the tenogenic phenotype of tendon derived cells and differentiate non-tendon derived cells (stem cells and dermal fibroblasts) towards the tenogenic lineage, subsequently enabling development of three-dimensional cell-assembled tissue equivalents, the clinical potential of which will be assessed in suitable preclinical models. The comprehensive Tendon Therapy Train programme will equip researchers with transferable inter- and multidisciplinary skills that will further European-based knowledge, innovation, competitiveness and leadership in the field of TESA / ATMP and ultimately enable clinical translation and commercialisation of the developed technologies.", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-02-01"], "Project_ID": ["676338"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["NATIONAL UNIVERSITY OF IRELAND GALWAY"], "EU_Contribution": ["EUR 2 194 800"], "Project_Title": ["Career Development and Mobility Fellowships in Medical Device Research and Development: A C\u00daRAM Industry-Academia Training Initiative."], "Total_Cost": ["EUR 4 389 600"], "Country": ["Ireland"], "Project_ACR": ["MedTrain"], "Technology_Description": "MedTrain is a new Industry-Academia Training, Career Development, and Mobility Fellowship Programme in Medical Device Research and Development at C\u00daRAM. C\u00daRAM, the national Centre for Research in Medical Devices, is a distributed research centre, headquartered in the National University of Ireland, Galway (NUIG), and composed of multiple academic partners from around Ireland (NUIG, University College Dublin (UCD), University College Cork (UCC), Royal College of Surgeons in Ireland (RCSI), Molecular Medicine Ireland) and 35+ industry partners. MedTrain will offer 31 prestigious two-year postdoctoral fellowships for incoming mobility to eligible Experienced Researchers in the area of Medical Device Research and Development across two calls. Experienced researchers, by definition under Marie Sk\u0142odowska-Curie Actions (MSCA), are those in possession of a doctoral degree (or at least four years full-time equivalent research experience) at the time of the recruitment by the host organisation. Fellowships must comply with the MSCA mobility rule. Career breaks will be taken into account. Fellowships are open to candidates of any nationality who shall not have resided or carried out their main activity (work, studies, etc.) in Ireland for more than 12 months in the three years immediately prior to the time of recruitment by the host organisation. Compulsory national service and/or short stays such as holidays are not taken into account. MedTrain is based on individual-driven mobility, meaning that fellows will have the freedom to choose their research area (provided it falls within the remit of C\u00daRAM), their supervisor and their secondment organisation. Fellows will be hosted in a C\u00daRAM academic host organisation (NUIG, UCC, UCD, RCSI) and will second to a suitable research performing organisation in the non-academic sector, located in any country in the world appropriate to meet the needs of the fellows\u2019 research, training and career development requirements.", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2015-FP - Marie Sk\u0142odowska-Curie Co-funding of regional, national and international programmes (COFUND-FP)"], "Funding_scheme": ["MSCA-COFUND-FP - Fellowship programmes"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["713690"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2015"]}, -{"Partners": ["CENTRE D ESTUDIS DEMOGRAFICS", "CENTRE D ESTUDIS DEMOGRAFICS"], "EU_Contribution": ["EUR 1 174 500"], "Project_Title": ["Equalizing or disequalizing? Opposing socio-demographic determinants of the spatial distribution of welfare."], "Total_Cost": ["EUR 1 174 500"], "Country": ["Spain", "Spain"], "Project_ACR": ["EQUALIZE"], "Technology_Description": "This project aims to investigate the extent to which current trends in family formation, living arrangements and gender-specific education levels are related to the spatial distribution of welfare and the emergence of jobless households in contemporary societies. Inter alia, we aim to explore whether the welfare disequalizing, impoverishing and polarizing effects that are currently associated with recent patterns in assortative mating, lone parenthood and household composition are offset by an unprecedented phenomenon that is sweeping the world during the last decades: the rapid process education expansion in tandem with a reversal of the gender gap in education. The extent to which these two opposing forces occur and which of them is more influential in shaping the distribution of welfare between and within countries is among the main goals of this project. To this end, we will draw upon a variety of household surveys and the world largest sources of census microdata: the Integrated Public Use Microdata Series (IPUMS) project and the Latin American and Caribbean Demographic Centre. Because of their unparalleled geographical coverage and detail, these sources of data constitute exceptional instruments to study socio-demographic phenomena that have been vastly underutilized by the international research community. Triangulating our analysis at the micro, meso and macro levels, we will establish formal linkages between welfare distributions and its socio-demographic correlates to unveil insightful relationships that have been unsatisfactorily explored so far because of the lack of appropriately harmonized, sufficiently detailed and georeferenced datasets. We will strongly emphasize the spatial distribution of variables to unravel local patterns that might take place at highly disaggregated levels, therefore not being discernible to traditional (not as finely-grained) approaches.", "To": ["2020-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2015-05-01"], "Project_ID": ["637768"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["OSLO UNIVERSITETSSYKEHUS HF", "ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON", "UNIVERSITAT POLITECNICA DE VALENCIA", "KNIGHT SCIENTIFIC LIMITED", "UNIVERSITETET I OSLO"], "EU_Contribution": ["EUR 3 031 375"], "Project_Title": ["A paradigm shift in cancer therapy \u2013 using mitochondria-powered chemiluminescence to non-invasively treat inaccessible tumours"], "Total_Cost": ["EUR 3 031 375"], "Country": ["Norway", "Greece", "Spain", "United Kingdom", "Norway"], "Project_ACR": ["Lumiblast"], "Technology_Description": "Brain cancers such as glioblastoma multiforme (GBM) are practically incurable due to their location, invasiveness and highly aggressive nature. The use of light-based treatments of GBM by activating tumor-localized photosensitizers, such as in photodynamic therapy (PDT) has been clinically evaluated, but with limited success. This is mainly due to the limited penetration of light into tissue and the efficient spread of tumor cells typically up to at least 2 cm from the resection margin. Moreover, the existing photon based treatments (photodynamic therapy) are highly invasive and usually require open-cranium surgery, due to the need for external light sources. In the Lumiblast project the photons are produced inside the tumor cells in the form of chemiluminescence avoiding the major limitation of using external light to treat solid, deep-sited and inaccessible tumors. The principle utilized in Lumiblast may also be relevant for cancers of other origins. Due to its nature Lumiblast is expected to act on individual cells, rather than the collective lesion; it could thus completely eliminate the hitherto incurable GBM. Each GBM cell is expected to become a small lamp providing the light required for the photosensitive agents to become activated, killing the tumour cells from the inside. Lumiblast requires a concerted interdisciplinary action. The project coordinator (Berg\u2019s group, Oslo University Hospital, OUS) is world renowned in PDT and photomedicine, while the team from the University of Athens (Georgios Vougioukalakis\u2019 group, UoA) is up and coming with high expertise in synthetic chemistry. The Polytechnic University of Valencia (Miguel Miranda\u2019s group, UPV) team is headed by a world leader in Photochemistry, the University of Oslo partner (Hanne H. T\u00f8nnensen\u2019s group, UiO) is specialized in pharmaceutical formulation, and Knight Scientific Ltd (KSL, CEO Jan Knight) is an SME with an impressive track record in ROS-activated luminescence. This 4.5-year project will establish the Lumiblast breakthrough technology by providing proof-of-concept in extracellular systems, GBM cell cultures and animal models, with the vision to advance Lumiblast to the clinic 5-6 years after the end of the proposed project.", "To": ["2021-03-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-1-2014 - FET-Open research projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["712921"], "Call_for_Proposal": ["H2020-FETOPEN-2014-2015-RIA"]}, -{"Partners": ["EUROPEAN CENTRE FOR MEDIUM-RANGE WEATHER FORECASTS", "METEO-FRANCE", "INSTITUT ROYAL METEOROLOGIQUE DE BELGIQUE", "DANMARKS METEOROLOGISKE INSTITUT", "EIDGENOESSISCHES DEPARTEMENT DES INNERN", "DEUTSCHER WETTERDIENST", "LOUGHBOROUGH UNIVERSITY", "NATIONAL UNIVERSITY OF IRELAND GALWAY", "INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK", "BULL SAS", "NVIDIA SWITZERLAND AG", "OPTALYSYS"], "EU_Contribution": ["EUR 3 977 952,50"], "Project_Title": ["Energy-efficient SCalable Algorithms for weather Prediction at Exascale"], "Total_Cost": ["EUR 3 977 952,50"], "Country": ["United Kingdom", "France", "Belgium", "Denmark", "Switzerland", "Germany", "United Kingdom", "Ireland", "Poland", "France", "Switzerland", "United Kingdom"], "Project_ACR": ["ESCAPE"], "Technology_Description": "ESCAPE will develop world-class, extreme-scale computing capabilities for European operational numerical weather prediction (NWP) and future climate models. The biggest challenge for state-of-the-art NWP arises from the need to simulate complex physical phenomena within tight production schedules. Existing extreme-scale application software of weather and climate services is ill-equipped to adapt to the rapidly evolving hardware. This is exacerbated by other drivers for hardware ", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["FETHPC-1-2014 - HPC Core Technologies, Programming Environments and Algorithms for Extreme Parallelism and Extreme Data Applications"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-10-01"], "Project_ID": ["671627"], "Call_for_Proposal": ["H2020-FETHPC-2014"]}, -{"Partners": ["EBERHARD KARLS UNIVERSITAET TUEBINGEN", "CARL VON OSSIETZKY UNIVERSITAET OLDENBURG", "UNIVERSITETET I BERGEN", "THE UNIVERSITY OF SUSSEX", "KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW", "TECHNISCHE UNIVERSITAET WIEN", "UNIVERSITAET INNSBRUCK", "CONSIGLIO NAZIONALE DELLE RICERCHE", "MULTI CHANNEL SYSTEMS MCS GMBH", "EKB TECHNOLOGIES LTD", "INILABS GMBH"], "EU_Contribution": ["EUR 3 867 784,92"], "Project_Title": ["In the eye of the observer: Visual processing at the heart of the retina"], "Total_Cost": ["EUR 3 867 784,92"], "Country": ["Germany", "Germany", "Norway", "United Kingdom", "Netherlands", "Austria", "Austria", "Italy", "Germany", "Israel", "Switzerland"], "Project_ACR": ["switchBoard"], "Technology_Description": "All visual information is broadcasted by an intra-retinal pathway formed by a group of neurons called bipolar cells. They collect photoreceptor signals in the outer retina and relay the signals to the inner retinal neurons. This transfer of visual information is far from passive: Each of the at least 10 bipolar cell types transforms the photoreceptor signals in a unique and highly specific way. As a result, the bipolar cell output signals form the first \u201celementary operations\u201d from which the neural circuits of the inner retina compose a feature-oriented description of the visual world. Reflecting the partitioning of visual information into parallel channels, the retinal layer in which bipolar cell axon terminals meet their synaptic partners, is highly organized: This so-called \u201cinner plexiform layer\u201d effectively serves as the retina\u2019s \u201cswitch board\u201d: The input is provided by the different bipolar cell \u201cchannels\u201d, while the output is carried by an even larger number of channels, represented by ganglion cells that form the optic nerve. Each of the ~20 ganglion cell types composes its feature-extracting circuits from a specific set of bipolar cell input it receives. Owing to its regular structure and ease of experimental access, the retina is amongst the best understood self-standing neuronal networks in neuroscience. Indeed, recent advances hold the exciting promise that an in-depth understanding of the bipolar cells \u2013 an entire class of neurons \u2013 and their role in the first critical steps of visual processing is within reach. Our proposal aims to train young researchers in world-leading research labs towards completing this goal. We will accomplish this by exposing the students to a host of cutting-edge techniques and a broad spectrum of research approaches within the training network \u2013 from imaging at synaptic resolution, transgenetics and retina degeneration models to the application of retinal circuit principles for signal processing in artificial vision chips.", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-11-01"], "Project_ID": ["674901"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["TECHNISCHE UNIVERSITAET DRESDEN", "NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU", "VYSOKA SKOLA BANSKA - TECHNICKA UNIVERZITA OSTRAVA", "NATIONAL UNIVERSITY OF IRELAND GALWAY", "INTEL CORPORATION SAS", "TECHNISCHE UNIVERSITAET MUENCHEN", "GNS MBH GESELLSCHAFT FUR NUMERISCHE SIMULATION MBH"], "EU_Contribution": ["EUR 3 534 198,75"], "Project_Title": ["Runtime Exploitation of Application Dynamism for Energy-efficient eXascale computing"], "Total_Cost": ["EUR 3 534 198,75"], "Country": ["Germany", "Norway", "Czech Republic", "Ireland", "France", "Germany", "Germany"], "Project_ACR": ["READEX"], "Technology_Description": "High Performance Computing (HPC) has become a major instrument for many scientific and industrial fields to generate new insights and product developments. There is a continuous demand for growing compute power, leading to a constant increase in system size and complexity. Efficiently utilizing the resources provided on Exascale systems will be a challenging task, potentially causing a large amount of underutilized resources and wasted energy. Parameters for adjusting the system to application requirements exist both on the hardware and on the system software level but are mostly unused today. Moreover, accelerators and co-processors offer a significant performance improvement at the cost of increased overhead, e.g., for data-transfers.", "To": ["2018-08-31, ongoing project |"], "Meta": [""], "Topic_s": ["FETHPC-1-2014 - HPC Core Technologies, Programming Environments and Algorithms for Extreme Parallelism and Extreme Data Applications"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-09-01"], "Project_ID": ["671657"], "Call_for_Proposal": ["H2020-FETHPC-2014"]}, -{"Partners": ["NATIONAL UNIVERSITY OF IRELAND GALWAY"], "EU_Contribution": ["EUR 233 555,40"], "Project_Title": ["Genome editing for spatiotemporal analysis of centriolar SATellite BIOgenesis and FUNction in cellular stress responses"], "Total_Cost": ["EUR 233 555,40"], "Country": ["Ireland"], "Project_ACR": ["SATBIOFUN"], "Technology_Description": "The centrosome is the major microtubule-organizing centre of a cell. It also serves as the base for the primary cilium, an antenna-like structure that allows cells to respond to external stimuli. Around the centrosome lie a number of electron dense cytoplasmic granules, termed centriolar satellites. These are involved in protein trafficking and are crucial for normal centrosome and cilium assembly and function. However, little is known about satellite composition, biogenesis or regulation. Mutations in a number of genes encoding satellite proteins cause ciliopathies, demonstrating their importance in the etiology of disease. Emerging data also shows that satellites contribute to the cellular stress response. The central scientific goal of this proposal is to systematically dissect, for the first time, the molecular mechanisms underpinning centriolar satellite biogenesis and function. Coupling genome-editing and cutting-edge imaging techniques we will perform morphometric quantitative analysis of satellite proteins to delineate their specific role in the cellular response to stress. This project encompasses an Outgoing Phase during which the Fellow will be trained in advanced, high-content, automated, and super-resolution microscopy, and computational analysis to study satellite biogenesis and function. Within this phase a secondment to the biotech sector will occur during which the Fellow will learn cutting-edge DNA manipulation methods. The Return Phase allows the transfer of this knowledge to Europe whilst the Fellow receives training in the analysis of stress responses. Alongside this the Fellow will follow a program of courses to acquire a range of complementary skills, including industry-related skills and teaching qualifications. Together, this will accomplish the overarching objective of developing the Fellow\u2019s career to a position of professional maturity, thereby facilitating her long-term goal of establishing her own independent research group in Europe.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-07-01"], "Project_ID": ["702601"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["NATIONAL UNIVERSITY OF IRELAND GALWAY", "NATIONAL UNIVERSITY OF IRELAND GALWAY"], "EU_Contribution": ["EUR 891 386"], "Project_Title": ["Voices Of Individuals: Collectively Exploring Self-determination"], "Total_Cost": ["EUR 891 386"], "Country": ["Ireland", "Ireland"], "Project_ACR": ["VOICES"], "Technology_Description": "The right to make one\u2019s own decisions and to have these decisions respected by law is a basic human freedom which most adults take for granted. However, for many people with disabilities (especially people with intellectual, psycho-social and other cognitive disabilities) this fundamental right has been denied \u2013 informally, in the private sphere, and formally, in the public sphere through States\u2019 laws and policies. ", "To": ["2018-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-06-01"], "Project_ID": ["638768"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["ERDYN CONSULTANTS", "ZENTRUM FUR SOZIALE INNOVATION GMBH", "RISE RESEARCH INSTITUTES OF SWEDEN AB", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "AGENCE NATIONALE DE LA RECHERCHE"], "EU_Contribution": ["EUR 799 837,50"], "Project_Title": ["Tools and Actions for Impact Assessment and Policy makers Information"], "Total_Cost": ["EUR 873 442,50"], "Country": ["France", "Austria", "Sweden", "Switzerland", "France"], "Project_ACR": ["TAIPI"], "Technology_Description": "TAIPI, Tools and Actions for Impact Assessment and Policy makers Information, is a CSA proposal to the \u201cPolicy environment for FET Flagships\u201d topic of the call H2020-FETFLAG-2014. TAIPI addresses the scope of the this topic by undertaking actions related to: (i) Assessing the impacts of FET Flagship initiatives, including through metrics and indicators; (ii) Collection of information need for policy making, e.g. through consultation actions and surveys. The general objective of TAIPI is to support and strengthen the FET Flagship Initiative and the two selected Flagships. Specific objectives of TAIPI are: (i) To develop assessment methodologies along with the required toolkits which will be applied respectively to HBP and Graphene Flagships, (ii) To carry out the impact assessment of both Flagships and the Flagship policy by applying the specifically developed methodology and tools, (iii) To collect and provide information for policy makers and funding organizations participating to Flagships initiative, (iv) To transfer to the Flagships these developed toolkits, and to enable them to use these tools after the end of the CSA, thus ensuring the sustainability of the project activities. TAIPI is composed of 5 work packages: WP1 Management, WP2 Development of methodology, WP3 Impact assessment, WP4 Support to policy makers, WP5 Dissemination. TAIPI will assess the impacts of HBP and Graphene, enhance the flow of information from the Flagships towards policy makers, relevant stakeholders and wider public, improve the understanding of the impacts of the Flagships on science, technology, economy and society and contribute to create a stable and structured environment for the benefit of the FET Flagships. The environment created by TAIPI will thus benefit to the Flagships, allowing them to concentrate on the fields where they bring the highest added value to their stakeholders while they rely on up-to-date tools, developed by TAIPI, to monitor in real time their impacts.", "To": ["2017-12-31, closed project"], "Meta": [""], "Topic_s": ["FETFLAG-2-2014 - 2014: Policy environment for FET Flagships"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["France"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["650029"], "Call_for_Proposal": ["H2020-FETFLAG-2014"]}, -{"Partners": ["FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS", "UNIVERSITE CLERMONT AUVERGNE", "UNIVERSITE BLAISE PASCAL CLERMONT-FERRAND II", "THE UNIVERSITY OF SUSSEX", "RIJKSUNIVERSITEIT GRONINGEN", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "KARLSRUHER INSTITUT FUER TECHNOLOGIE"], "EU_Contribution": ["EUR 2 892 500"], "Project_Title": ["Mind and Time: Investigation of the Temporal Traits of Human-Machine Convergence"], "Total_Cost": ["EUR 2 892 500"], "Country": ["Greece", "France", "France", "United Kingdom", "Netherlands", "United Kingdom", "Germany"], "Project_ACR": ["TIMESTORM"], "Technology_Description": "Contemporary research endeavours aim at equipping artificial systems with human-like cognitive skills, in an attempt to promote their intelligence beyond repetitive task accomplishment. However, despite the crucial role that the sense of time has in human cognition, both in perception and action, the capacity of artificial agents to experience the flow of time remains largely unexplored. The inability of existing systems to perceive time constrains their potential understanding of the inherent temporal characteristics of the dynamic world, which in turn acts as an obstacle to their symbiosis with humans. Time perception is without doubt, not an optional extra, but a necessity for the development of truly autonomous, cognitive machines.", "To": ["2018-06-30, ongoing project"], "Meta": [""], "Topic_s": ["FETPROACT-2-2014 - Knowing, doing, being: cognition beyond problem solving"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Greece"], "Activity": ["Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-01-01"], "Project_ID": ["641100"], "Call_for_Proposal": ["H2020-FETPROACT-2014"]}, -{"Partners": ["UNIVERSITETET I OSLO", "UNIVERSITETET I OSLO"], "EU_Contribution": ["EUR 1 495 079"], "Project_Title": ["Enacting the Good Economy: Biocapitalization and the little tools of valuation"], "Total_Cost": ["EUR 1 495 079"], "Country": ["Norway", "Norway"], "Project_ACR": ["LITTLE TOOLS"], "Technology_Description": "What shall we live off in the future? Where will our food come from, and what will form the basis for our economies? A so-called \u201cblue revolution\u201d, where fish become farmed rather than caught, is increasingly presented as an answer to the above questions. This transformation of the economy exemplifies ongoing efforts to produce new forms of capital out of the ordering and reordering of life. These processes are intimately related to the expanding life sciences, the bioeconomy and what is sometimes called new forms of biocapital.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["637760"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["UNIVERSITAET ZU KOELN", "UNIVERSITAET ZU KOELN", "UNIVERSITAET BREMEN"], "EU_Contribution": ["EUR 1 125 575"], "Project_Title": ["Enhanced Qualitative and Multi-Method Research in Political Science"], "Total_Cost": ["EUR 1 125 575"], "Country": ["Germany", "Germany", "Germany"], "Project_ACR": ["ENHANCEDQMMR"], "Technology_Description": "Over the last 20 years, qualitative methods in political science have developed rapidly on three dimen-sions. First, set theory was formulated as an alternative to what is called the quantitative worldview. Second, process tracing for the analysis of mechanisms evolved as a complement to the estimation of marginal effects. Process tracing has also been tied to Bayesianism as opposed to frequentism. Third, process tracing became an element of multi-method research (MMR), integrating it with frequentist statistics or Qualitative Comparative Analysis (QCA). ", "To": ["2020-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-05-01"], "Project_ID": ["638425"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["THE UNIVERSITY OF EDINBURGH", "INTEL GMBH", "INTEL DEUTSCHLAND GMBH", "FUJITSU TECHNOLOGY SOLUTIONS GMBH", "BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION", "TECHNISCHE UNIVERSITAET DRESDEN", "ALLINEA SOFTWARE LIMITED", "EUROPEAN CENTRE FOR MEDIUM-RANGE WEATHER FORECASTS", "ARCTUR RACUNALNISKI INZENIRING DOO"], "EU_Contribution": ["EUR 8 114 504"], "Project_Title": ["Next Generation I/O for Exascale"], "Total_Cost": ["EUR 8 114 504"], "Country": ["United Kingdom", "Germany", "Germany", "Germany", "Spain", "Germany", "United Kingdom", "United Kingdom", "Slovenia"], "Project_ACR": ["NEXTGenIO"], "Technology_Description": "The overall objective of the Next Generation I/O Project (NEXTGenIO) is to design and prototype a new, scalable, high-performance, energy efficient computing platform designed to address the challenge of delivering scalable I/O performance to applications at the Exascale. It will achieve this using highly innovative, non-volatile, dual in-line memory modules (NV-DIMMs). These hardware and systemware developments will be coupled to a co-design approach driven by the needs of some of today\u2019s most demanding HPC applications. By meeting this overall objective, NEXTGenIO will solve a key part of the Exascale challenge and enable HPC and Big Data applications to overcome the limitations of today\u2019s HPC I/O subsystems.", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["FETHPC-1-2014 - HPC Core Technologies, Programming Environments and Algorithms for Extreme Parallelism and Extreme Data Applications"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-10-01"], "Project_ID": ["671591"], "Call_for_Proposal": ["H2020-FETHPC-2014"]}, -{"Partners": ["UNIVERSITAET ZU KOELN", "UNIVERSITAET ZU KOELN"], "EU_Contribution": ["EUR 1 965 250"], "Project_Title": ["Reading Global. Constructions of World Literature and Latin America"], "Total_Cost": ["EUR 1 965 250"], "Country": ["Germany", "Germany"], "Project_ACR": ["RG"], "Technology_Description": "The debate on world literature is among the most significant cultural historical controversies of our time. This contribution to the debate aims to pursue two goals in particular:", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["646714"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["THE UNIVERSITY OF SUSSEX"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Healing from Enclosure: A Political Agroecology of a Science-and-Society Potato Controversy in Belgium"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["HealingFromEnclosure"], "Technology_Description": "Against the background of the ongoing crisis of the world\u2019s food systems, this research project investigates how agricultural knowledge shapes, and is shaped by, its broader cultural, economic, socio-technical and socio-ecological context. A transdisciplinary approach \u2013theoretically and empirically explorative, methodologically innovative, and action-oriented\u2014to the production, transmission and application of agricultural knowledge in Belgium, and Europe more broadly, offers a powerful way of thinking about the complex relationships that exist between food systems and agricultural knowledge. ", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["707807"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "FUNDACION PARA EL FOMENTO DE LA INVESTIGACION SANITARIA Y BIOMEDICA DE LA COMUNITAT VALENCIANA"], "EU_Contribution": ["EUR 1 671 875"], "Project_Title": ["Integrating genomics, epidemiology and evolution to accelerate tuberculosis eradication"], "Total_Cost": ["EUR 1 671 875"], "Country": ["Spain", "Spain", "Spain"], "Project_ACR": ["TB-ACCELERATE"], "Technology_Description": "When the scale of the tuberculosis (TB) epidemic was highlighted by its declaration as a \"Global Emergency\" by WHO in 1993, it was envisaged that the efficient use of existing tools would result in a progressive decline towards eradication. This has not occurred. At the current pace of decline in TB incidence the Millennium objective to eradicate it by 2050 will not be met. Predictions of epidemiological models were inaccurate and current control programs and technologies have shown their limitations to control the transmission of the disease. To overcome these limitations we need a technological, methodological and conceptual leap forward that can reveal the unknowns of TB epidemiology. I propose whole genome sequencing (WGS) as the technology that can mediate this advance. While WGS has been applied mostly to retrospective datasets I propose to use it in prospective samples from a low-burden region at a population scale. Genome information will fill the gap between epidemiology and evolution to have a direct impact on public health. This will allow to develop innovative methodologies to describe transmission at an unprecedented resolution and as a consequence to differentiate among risks factors associated to the bacteria, the host, the environment and their interactions. Elucidation of these factors will lead to better models used to design new strategies and accelerate global TB eradication. In addition, I will show how the real-time integration of data in public eHealth systems combined with in situ interventions will accelerate TB eradication. The strength of the project resides in its multidisciplinary approach to TB epidemiology that will provide answers to yet-out-of-reach questions. It will lead to improving health status at the local level as well as to epidemiological and control programs at a global scale. In summary, the project will open new ways to foster the long sought outcome of the tuberculosis community: TB eradication.", "To": ["2020-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations"], "From": ["2015-07-01"], "Project_ID": ["638553"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["NATIONAL UNIVERSITY OF IRELAND GALWAY", "NATIONAL UNIVERSITY OF IRELAND GALWAY"], "EU_Contribution": ["EUR 149 101"], "Project_Title": ["Medically Licensed Mesenchymal Stem Cells for Acute Respiratory Distress Syndrome."], "Total_Cost": ["EUR 149 101"], "Country": ["Ireland", "Ireland"], "Project_ACR": ["CCMI-ARDS"], "Technology_Description": "Acute Respiratory Distress Syndrome (ARDS) is a devastating condition, which kills 40% of sufferers, resulting in hundreds of thousands of deaths worldwide annually. Despite decades of intensive research efforts, there are no clinical therapeutic strategies available for this catastrophic condition. In our ERC Starter Grant, HA-NFkB-VILI, we have shown Mesenchymal Stem Cells (MSCs) to be beneficial in several relevant preclinical ARDS models. ", "To": ["2015-12-31, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2014 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-01-01"], "Project_ID": ["641392"], "Call_for_Proposal": ["ERC-2014-PoC"]}, -{"Partners": ["UNIVERSITETET I OSLO", "UNIVERSITETET I OSLO"], "EU_Contribution": ["EUR 1 499 572"], "Project_Title": ["Bivariational Approximations in Quantum Mechanics and Applications to Quantum Chemistry"], "Total_Cost": ["EUR 1 499 572"], "Country": ["Norway", "Norway"], "Project_ACR": ["BIVAQUM"], "Technology_Description": "The standard variational principles (VPs) are cornerstones of quantum mechanics, and one can hardly overestimate their usefulness as tools for generating approximations to the time-independent and time-dependent Schr\u00f6odinger equations. The aim of the proposal is to study and apply a generalization of these, the bivariational principles (BIVPs), which arise naturally when one does not assume a priori that the system Hamiltonian is Hermitian. This unconventional approach may have transformative impact on development of ab initio methodology, both for electronic structure and dynamics.", "To": ["2020-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-04-01"], "Project_ID": ["639508"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["UNIVERSITAET ZU KOELN"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Costs and optimality of gene expression levels in Escherichia coli"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["OPTEX"], "Technology_Description": "The precise expression of protein coding genes is of crucial importance to all organisms, since proteins are involved in virtually all vital processes. Some proteins need to be available at exactly the right amount to perform cellular functions sustainably and thereby maximize fitness. Consequently, gene expression needs to be accurately controlled. For these reasons, it has been hypothesized that cells evolve towards a state in which expression levels are optimally tuned to maximize fitness in the current environment. The cell\u2019s growth and resource distribution is constrained by tradeoffs between the costs and benefits of a particular expression level. Recent investigations of the global effects of protein levels provide insights into the mutual dependency between expression and growth. To test this central hypothesis in systems biology, we use Escherichia coli which is the best-characterized model organism for fundamental research on gene expression, as well as for biotechnological applications. We aim to advance the understanding of the costs and benefits of expression by systematically investigating its ~4000 genes with gene deletion- and expression libraries. The effect of the expression level for each gene on fitness will be quantified through precise high throughput growth rate measurements. We will dissect general cellular cost-factors from gene specific effects which allow us to systematically uncover the mechanistic causes of the cost of protein overexpression. The burden manifests in universal protein biosynthesis costs but also specific costs such as eventual detrimental effects. The benefits are determined by the function of a protein: metabolic activity, structural component, and other roles. We will test if these contributions collectively converge to an optimum to maximize fitness. Optimality is a common objective in man-made systems and engineering and it will be intriguing to learn how natural selection has shaped cells according to this concept.", "To": ["2019-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-02-01"], "Project_ID": ["707352"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["NATIONAL UNIVERSITY OF IRELAND GALWAY"], "EU_Contribution": ["EUR 175 866"], "Project_Title": ["Mathematical modelling of soft tissues"], "Total_Cost": ["EUR 175 866"], "Country": ["Ireland"], "Project_ACR": ["SOFT-TISSUES"], "Technology_Description": "Dr Valentina Balbi is an Italian national, trained in Applied Mathematics in Italy and in Mechanics in France and at Stanford University. She publishes articles in high-impact factor journals, at the frontiers of applied mathematics and other disciplines. She is requesting funds for two years, to work with Professor Michel Destrade and join his group of Biomechanics at NUI Galway, Ireland.", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-03-01"], "Project_ID": ["705532"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE UNIVERSITY OF SUSSEX"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["A Quantum Boost for Atomic Sensors"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["QBAS"], "Technology_Description": "Atom interferometry provides extremely sensitive measurements of quantities such as rotations and accelerations. This project will theoretically investigate how quantum entanglement between atoms and photons can enhance the sensitivity of atom-interferometry. The aim of this project is to drastically enhance the sensitivity of atom interferometers, to deliver practical sensing devices of unprecedented sensitivity. This increased sensitivity may lead to new technologies, such as ultra-sensitive gravity gradiometers for the detection of mineral reserves, as well as important applications to fundamental physics, such as tests of fundamental theories beyond the standard model.", "To": ["2018-08-08, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-08-09"], "Project_ID": ["704672"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["BCAM - BASQUE CENTER FOR APPLIED MATHEMATICS"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Forecast of time-varying effects of post-GFC monetary policy + a novel computing application"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["Post-GFC Monetary Policy"], "Technology_Description": "Central banks worldwide routinely use models in assessing and forecasting the global and domestic economic outlook in order to determine the most suitable monetary policies. Economies evolve over time and policies that worked in the 1980s might not be viable at the present time, thus models must be flexible to account for these changes. Undoubtedly, it is difficult to identify the exact point in time when a change in macroeconomic behaviour occurs, particularly a change that will trigger a reactive monetary policy to neutralise its negative effects. The current project proposes a new methodology, which due to its local nature can react faster to changes in the process than other existing methodologies. This project aims at breaking new ground in several respects. First, by proposing for the first time a nonparametric local linear estimator of multivariate processes with possible smooth or abrupt changes in the parameters. Second, by developing a user-friendly computational package with the aforementioned functionality. Finally, by investigating the effect for G7 and Eurozone economies of the monetary policies driven by the global financial crisis.", "To": ["2018-01-19, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2016-01-20"], "Project_ID": ["657182"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["PHILIPPS UNIVERSITAET MARBURG"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Functional characterization of the cell division inhibitor MipZ"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["MIPZ"], "Technology_Description": "Correct positioning of the division plane is essential for the generation of normal offspring. In Caulobacter crescentus, the spatiotemporal control of cell division is mediated by MipZ, a conserved P-loop ATPase forming bipolar gradients with a concentration minimum at the cell centre. Antagonizing the polymerization of the essential divisome component FtsZ, MipZ inhibits divisome assembly near the poles, thereby limiting cytokinesis to midcell. Gradient formation involves a dynamic localization cycle, in which freely diffusible MipZ monomers interact with polar complexes of the centromere-binding protein ParB and then dimerize in an ATP-dependent manner. Dimers dissociate from ParB and are immobilized within the cell through non-specific interaction with chromosomal DNA. Spontaneous ATP hydrolysis triggers disassembly of the complex, releasing MipZ monomers that are recaptured by ParB. How ParB stimulates dimer formation and how DNA-bound dimers inhibit FtsZ assembly is still unknown. We will address these questions by characterizing previously isolated MipZ mutants with FtsZ/ParB interaction defects, using a combination of fluorescence microscopy, two-hybrid analysis, biochemistry, and biophysical techniques such as surface plasmon resonance, microscale thermophoresis or hydrogen-deuterium-exchange mass spectrometry. We will also use synthetic biological and modelling approaches to rebuild the system in a simplistic form to thus gain in-depth knowledge of the function of the different elements.", "To": ["2017-08-02, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-08-03"], "Project_ID": ["659174"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITAET ZU KOELN", "UNIVERSITAET ZU KOELN"], "EU_Contribution": ["EUR 1 683 120"], "Project_Title": ["Using cis-regulatory mutations to highlight polygenic adaptation in natural plant systems"], "Total_Cost": ["EUR 1 683 120"], "Country": ["Germany", "Germany"], "Project_ACR": ["AdaptoSCOPE"], "Technology_Description": "The goal of this project is to demonstrate that novel aspects of the molecular basis of Darwinian adaptation can be discovered if the polygenic basis of adaptation is taken into account. This project will use the genome-wide distribution of cis-regulatory variants to discover the molecular pathways that are optimized during adaptation via accumulation of small effect mutations. Current approaches include scans for outlier genes with strong population genetics signatures of selection, or large effect QTL associating with fitness. They can only reveal a small subset of the molecular changes recruited along adaptive paths. Here, instead, the distribution of small effect mutations will be used to make inferences on the targets of polygenic adaptation across divergent populations in each of the two closely related species, A. thaliana and A. lyrata. These species are both found at diverse latitudes and show sign of local adaptation to climatic differences. Mutations affecting cis-regulation will be identified in leaves of plants exposed to various temperature regimes triggering phenotypic responses of adaptive relevance. Their distribution in clusters of functionally connected genes will be quantified. The phylogeographic differences in the distribution of the mutations will be used to disentangle neutral from adaptive clusters of functionally connected genes in each of the two species. This project will identify the molecular pathways subjected collectively to natural selection and provide a completely novel view on adaptive landscapes. It will further examine whether local adaptation occurs by convergent evolution of molecular systems in plants. This approach has the potential to find broad applications in ecology and agriculture.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["648617"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["THE UNIVERSITY OF SUSSEX", "THE UNIVERSITY OF SUSSEX", "UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 149 170"], "Project_Title": ["DHaptics: Creating silent and sharp Mid-air Haptics using phased array of ultrasound transducers"], "Total_Cost": ["EUR 149 170"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom"], "Project_ACR": ["DHaptics"], "Technology_Description": "A fundamental shift is underway in how we interact with our computers and devices. Products such as Microsoft\u2019s Kinect and Leap Motion\u2019s desktop controller enable us to dispose of the keyboard and mouse and instead control our devices without touching them. Touchless sensing products are being launched across the consumer electronics, automotive and healthcare industries. A significant and well noted problem with touchless sensing is a lack of tactile feedback.", "To": ["2016-05-31, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2014 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2014-12-01"], "Project_ID": ["640749"], "Call_for_Proposal": ["ERC-2014-PoC"]}, -{"Partners": ["ALFRED-WEGENER-INSTITUT HELMHOLTZ-ZENTRUM FUR POLAR- UND MEERESFORSCHUNG"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Up-scaling Arctic diversity analysis to link community organisation and ecosystem functioning"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["ARCDIV"], "Technology_Description": "Arctic oceans are undergoing major changes in many of its fundamental physical constituents, such as a shift from multi- to first-year ice, shorter ice-covered periods, increasing freshwater runoff, and warming and alteration in the distribution of water masses. Such changes, often resulting from anthropogenic stressors, have profound impacts on the chemical and biological processes that are at the root of Arctic marine food webs, influencing their structure, function and biodiversity. Yet, much research addressing these on-going changes is practically and financially limited to local scales or rather exploratory by nature, making it imperative to better characterise and understand the structural and functional diversity of ecological systems that contribute to the marine Arctic across larger scales. We aim to offer more insight in the distributions and abundance of macrobenthic species in Arctic seascapes, e.g. bivalves, polychaetes, and crustaceans that live in marine soft bottoms. Building on recent pan-Arctic community data from ~5000 locations, we address a fundamental challenge in Arctic ecological research by employing quantitative methods thus far not feasible. We will use multi-species distribution models that allow determining interactions between species; link functions to environmental characteristics using 4th-corner models. Key is that such approaches link traits and environment without the necessity of including sample locations, holding promise for an approach that translates ecosystem function directly to services; look for indirect interactions and feedbacks between polar benthic macrofauna and ecosystem functioning by employing structural equation models. This enables full inference of spatial diversity patterns of Arctic benthic communities and link community organisation and ecosystem functioning, allowing us to understand the interplay between fine- and broad-scale patterns and processes structuring rapidly changing polar benthic ecosystems.", "To": ["2018-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations"], "From": ["2016-06-01"], "Project_ID": ["700796"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["ETHNIKO IDRYMA EREVNON"], "EU_Contribution": ["EUR 164 653,20"], "Project_Title": ["Distributed vibrational and acoustic sensing technology"], "Total_Cost": ["EUR 164 653,20"], "Country": ["Greece"], "Project_ACR": ["DIVAS"], "Technology_Description": "The main target of the DIVAS project is the design and development of a low-cost opto-electronic interrogator for distributed vibration detection on standard communication optical fibers, based on Phase-OTDR technology (Phase-sensitive Optical Time Domain Reflectometry). This system is compatible with communication optical fiber devices, and it takes the advances of this innovating field. It will be developed through custom design of a set of electronic and optoelectronic components. Its distributed feature allows the collection of vibrational information along the entire optical fiber length, which is equivalent to thousands and thousands of inline sensors. This feature combined with extreme sensitivity, makes this interrogator an efficient low-price option in vibration detections. For reasons of cost effectiveness, communication optical fiber lines are, normally, adjacent to strategic buildings such us railway, gas, and petrol lines; using one of the available redundant optical fibers, it is possible to retrieve vibrational information for seismic security or for civil structural health monitoring. Using also specifically installed optical fibers, this interrogator may have a wide range of applications from environmental protection purposes (such as terrestrial fauna and marine life protection), to control of intrusions in a wide area (e.g. military context) or, finally, for security purposes such as monitoring nuclear power plants (in order to know if structural damages are approaching before a leakage occurs). The project aims for the development of a compact portable prototype, ready for field tests, which will be tried on at least in one civil engineering application (structural health monitoring), in collaboration with the academic partner. With the help of the industrial partner, the prototype will be adapted for the production line to reach the market with a competitive cost that will ensure its widespread dissemination in all possible fields.", "To": ["2018-06-07, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Greece"], "Activity": ["Research Organisations"], "From": ["2016-06-08"], "Project_ID": ["706221"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF EV"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Selective recovery of gallium from wastewaters of GaAs fabrication industry using siderophore based bisorptive biocomposites"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["GaLIophore"], "Technology_Description": "The projected use of GaAs and CIGS solar panel will lead to 137 tonnes deficit of Ga in 2020. As the Ga can only be economically mined as a by-product of bauxite mining which is not going to increase dramatically in near future, the only way to meet the projected EU requirement is by the recovery of Ga from scraps (LED waste) or GaAs fabrication industry wastewater. However, there is so far no commercially viable technology available.", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations"], "From": ["2016-10-01"], "Project_ID": ["704852"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["NATIONAL UNIVERSITY OF IRELAND GALWAY"], "EU_Contribution": ["EUR 248 063,40"], "Project_Title": ["Bioelectroreduction of nitrogen to ammonia: the incorporation of nitrogenase within enzymatic biological fuel cells for simultaneous production of electrical energy and ammonia."], "Total_Cost": ["EUR 248 063,40"], "Country": ["Ireland"], "Project_ACR": ["Bioelectroammonia"], "Technology_Description": "Enzymatic biological fuel cells (EBFCs) utilise enzymes as biological catalysts to produce electrical energy from chemical energy, usually being fuelled by simple molecules such as glucose or ethanol, in the presence of O2. This technology provides an alternative to the use of expensive metal catalysts (such as platinum) and offers the ability for electrical energy to be produced under much milder conditions, such as near-neutral pH and room temperature. The cathodes of EBFCs usually employ O2 as the oxidant and final electron acceptor; this proposal seeks to utilise N2 in its place. Not only does the use of N2 as the oxidant circumvent issues relating to dissolved O2 concentrations and solubility (limited to less than 1 mM), but it also presents the possibility to produce industrially important NH3 (using a novel technology) whilst simultaneously producing electrical energy.", "To": ["2018-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-06-01"], "Project_ID": ["654836"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE UNIVERSITY OF SHEFFIELD"], "EU_Contribution": ["EUR 251 857,80"], "Project_Title": ["Engineered Near-Infrared Photosynthesis"], "Total_Cost": ["EUR 251 857,80"], "Country": ["United Kingdom"], "Project_ACR": ["EngiNear-IR"], "Technology_Description": "Sunlight is the most abundant and sustainable energy source available to us. It drives photosynthesis, the source of all food and most energy resources on Earth. Phototrophic organisms use antenna complexes to absorb solar energy, and derived excitation energy migrates towards specialised pigment-protein complexes called reaction centres. Here, photosynthetic electron transfer is initiated, converting solar energy into a form that can be stored and used to power cell metabolism. The absorption characteristics of antenna and reaction centre complexes determine the specific wavelengths of light that can be captured and converted into chemical energy; light at other wavelengths is not used, representing a major limitation of light-harvesting efficiency. Improving this efficiency will play a key role in ensuring food and energy security for the future, a societal challenge to be met by the H2020 programme.", "To": ["2018-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-12-01"], "Project_ID": ["660652"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER", "THE UNIVERSITY OF EDINBURGH", "KAROLINSKA INSTITUTET", "CHARITE - UNIVERSITAETSMEDIZIN BERLIN", "SEREND-IP GMBH", "AQUILA BIOMEDICAL LIMITED", "REPRODUKTIIVMEDITSIINI TAK AS"], "EU_Contribution": ["EUR 346 500"], "Project_Title": ["Molecular Mechanisms of Endometriosis"], "Total_Cost": ["EUR 346 500"], "Country": ["Germany", "United Kingdom", "Sweden", "Germany", "Germany", "United Kingdom", "Estonia"], "Project_ACR": ["MOMENDO"], "Technology_Description": "Endometriosis (the presence of endometrial-like tissue or \u2018lesions\u2019 outside the uterus) is a chronic inflammatory disease affecting 6-10% of reproductive age women. It is associated with pelvic pain, painful periods, pain with sexual intercourse, and subfertility. The socioeconomic impacts of endometriosis are considerable. The recent WERF EndoCost study (a worldwide cost-of-illness study) reported that endometriosis reduced work productivity in 51% and negatively affected relationships in 50% of women with endometriosis. Current treatment options include invasive and repeated surgeries, or hormonal suppression with significant side effects analogous to a premature menopause. While several general concepts of the etiology of the disease such as retrograde menstruation, coelomic metaplasia, lymphovascular metastasis or the embryonic rest theory have been developed, the molecular mechanisms underlying the disease are currently still incompletely understood, hampering the development of efficient targeted therapies with limited side effects. MOMENDO utilizes the potential of an interdisciplinary consortium of leading world endometriosis experts to provide a deeper understanding of key molecular processes contributing to disease etiology and progression. By employing a wide range of experimental methods (biomarker and epigenetic studies on patient tissues, advanced animal models of the disease, proprietary atomic force microscopy for marker-free diagnostics) and novel and innovative conceptual approaches (adult stem cells, microRNAs, iron-induced inflammatory responses, novel endocrine concepts), MOMENDO will substantially contribute to a deeper understanding of the molecular mechanisms that explain the inflammatory pain associated with endometriosis and the persistent growth of endometriosis lesions. By combining the respective strengths of non-academic and clinical partners, MOMENDO expect to successfully translate these findings into novel therapeutic approaches.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-01-01"], "Project_ID": ["691058"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["UNIVERSITAET BIELEFELD", "UNIVERSITA DEGLI STUDI DELL'INSUBRIA", "EOTVOS LORAND TUDOMANYEGYETEM", "HELSINGIN YLIOPISTO", "UNIVERSITA DEGLI STUDI DI MILANO", "UNIVERSITAET ZU KOELN", "Orszagos Onkologiai Intezet", "HEIDELBERG PHARMA GMBH", "EXIRIS SRL"], "EU_Contribution": ["EUR 3 746 420,28"], "Project_Title": ["Peptide-Drug Conjugates for Targeted Delivery in Tumor Therapy"], "Total_Cost": ["EUR 3 746 420,28"], "Country": ["Germany", "Italy", "Hungary", "Finland", "Italy", "Germany", "Hungary", "Germany", "Italy"], "Project_ACR": ["MAGICBULLET"], "Technology_Description": "Many tumor cells are characterized by the overexpression of certain antigens. Molecules that specifically recognize these structures are suitable as homing devices in tumor therapy. Conjugates of anticancer drugs with such a delivery vector targeting tumors would be a \u201cmagic bullet\u201d according to the Nobel laureate Paul Ehrlich. Three antibody-drug conjugates (ADC) have already been approved for anticancer therapy. However, ADC have e.g. limitations with respect to tumor penetration, high manufacturing costs, and require challenging conjugation chemistry. Peptide-drug conjugates can have a high drug loading, easily penetrate tissue, and can be easily prepared in a homogenous form with straightforward and well-defined conjugation chemistry. ", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["642004"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["THE UNIVERSITY OF SUSSEX", "THE UNIVERSITY OF SUSSEX"], "EU_Contribution": ["EUR 149 645"], "Project_Title": ["The development, evaluation and commercialisation of an early years test of colour vision deficiency."], "Total_Cost": ["EUR 149 645"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["COLOURTEST"], "Technology_Description": "Colour vision deficiency (CVD) is a genetic disorder of colour vision that affects 7.4% of European males and 0.4% of European females. Although there are reliable tests for diagnosing CVD in adults and older children, there are only a few tests for young children, and fundamental issues with these tests render them unreliable. For example, colours used in the tests are too similar for young children to discriminate given their immature colour vision, tasks are too difficult for them to complete, tests either over- or under-diagnose CVD, or are not widely accessible. Therefore, the current situation is that CVD can be reliably diagnosed only from about 5 years onwards. Earlier diagnosis would enable steps to be taken to ensure CVD children are not disadvantaged in early years education that relies on colour coded schemes and materials. Our goal is to develop, evaluate and bring to market an age-appropriate early years test for CVD. Our research on the ERC funded \u2018CATEGORIES\u2019 project is investigating the development of colour perception in over 1400 infants and toddlers. This extensive testing has given us specialist insight into the exact colours that are appropriate for an early years test for CVD. We have also developed age-appropriate tasks that measure young children\u2019s responses to colour in a reliable and efficient manner. In the current project we propose to develop an early years CVD test in the form of an app. The test will use the colours that we have defined and the tasks that we have developed, and we aim for it to provide an accurate CVD diagnosis. The project will take the test to proof of concept and will establish the scientific validity, technical feasibility and commercialisation process. We aim that the test will be the \u2018gold standard\u2019 for educators, clinicians, scientists and parents. This will ensure that CVD can be detected earlier than is currently the case, bringing important and tangible benefits for education, clinical practice and research.", "To": ["2018-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2015 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-12-01"], "Project_ID": ["692694"], "Call_for_Proposal": ["ERC-2015-PoC"]}, -{"Partners": ["THE UNIVERSITY OF SUSSEX", "UMEA UNIVERSITET", "UNIVERSIDAD DE SEVILLA", "ROMA OKTATASI ALAP"], "EU_Contribution": ["EUR 207 000"], "Project_Title": ["Higher Education Internationalisation and Mobility: Inclusion, Equalities and Innovations"], "Total_Cost": ["EUR 207 000"], "Country": ["United Kingdom", "Sweden", "Spain", "Hungary"], "Project_ACR": ["HEIM"], "Technology_Description": "The proposed research/innovation project (HEIM) focuses on how principles of equity and inclusion can be applied to internationalisation strategies and programmes in higher education, at both staff and student levels. It focuses on the Roma community in Europe as a critical example of a marginalised group. HEIM will interrogate and develop the concept and practices of higher education internationalisation in Europe through questions about who is able to participate in and benefit from policy initiatives and strategic interventions. It asks whether certain social groups are disadvantaged or excluded from the opportunities that mobility offers. It will examine motivations and experiences, and the hidden costs of border crossings in terms of socio-political and affective considerations. Its objectives include comparative investigation of data on who is participating in selected internationalisation programmes; producing accounts based on literature, statistical data and empirical research. It will create a set of guidelines for reflexive and inclusive approaches to the internationalisation of higher education. Through its interdisciplinary and intersectoral approaches, it will contribute to methodological innovation across different fields. It will build research and innovation capacity by constructing teams and sharing knowledge between early stage and experienced researchers. It will exchange knowledge about internationalisation programmes in the partner organisations via co-written papers, statistical datasets, literature reviews, training and workshops. The Partnership is between three universities (Sussex, Ume\u00e5 and Seville) and a non-academic organisation, the Roma Education Fund (REF). Via secondments, staff exchange, training and collaborative inquiry, the project will investigate internationalisation policies, interventions and methodologies in different national locations.", "To": ["2017-12-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other"], "From": ["2015-01-01"], "Project_ID": ["643739"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["CENTRE D ESTUDIS DEMOGRAFICS"], "EU_Contribution": ["EUR 239 191,20"], "Project_Title": ["Family formation decisions and gender attitudes in crisis times: an international, historical and longitudinal comparison."], "Total_Cost": ["EUR 239 191,20"], "Country": ["Spain"], "Project_ACR": ["FAMilyDECisions"], "Technology_Description": "During the last decades, Spain has experienced not only an strong decrease on its fertility levels but also a significant delay in its timing to childbearing, so much so that it has been considered one of the countries with the lowest-low and latest-late fertility in the world. This research aims to better understand the reasons behind young adults\u2019 behaviors in family dynamics in a moment where it is possible to approach the impact of the economic crisis from different dimensions of the analysis. An extended scientific literature can be found about family formation dynamics and fertility, especially for European countries and mainly using a quantitative perspective. This mainly qualitative project proposes an innovative methodology to analyze the Spanish case from a three different perspectives of analysis: a cross-country comparison (five countries in 2012), an historical comparison (Spain 1985 vs. 2012) and a longitudinal comparison (Spain, same sample in 2012 and 2017). Furthermore, mixed methods will be applied considering the contextualization of qualitative data with quantitative data from census and surveys as complementary approaches; and the application of quantitative analysis to qualitative data. Main data from Spain in 2012 comes directly from the words of young adults in three different moments of their family formation decisions: i) to start a stable relationship; ii) to become parents; and iii) to expand the family after the first child. Main data consists of eighty (80) in-depth personal interviews already carried out to young adults between 24 and 35 years old, living in the Madrid and Barcelona metropolitan areas, that will be compared with an identical sample in the US, Sweden, Japan and Korea. Historical data comes from an existing comparable study from middle 80\u2019s in Spain and longitudinal data will be obtained after re-interview in 2017 the same sample interviewed in 2012 for Spain.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2016-10-01"], "Project_ID": ["657030"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE UNIVERSITY OF SUSSEX", "THE UNIVERSITY OF SUSSEX"], "EU_Contribution": ["EUR 149 630"], "Project_Title": ["HeartRater: Tools for the systematic evaluation of interoceptive ability"], "Total_Cost": ["EUR 149 630"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["HeartRater"], "Technology_Description": "The Proof-of-Concept grant seeks to develop a commercializable platform to quantify how sensitive individuals are to their own heartbeats. This platform will have applications in clinical psychology, personalized medicine and beyond.", "To": ["2018-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2015 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["693143"], "Call_for_Proposal": ["ERC-2015-PoC"]}, -{"Partners": ["INSTITUTO DE ASTROFISICA DE CANARIAS", "ISTITUTO NAZIONALE DI ASTROFISICA", "UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "STOCKHOLMS UNIVERSITET", "THE QUEEN'S UNIVERSITY OF BELFAST", "UNIVERSITY COLLEGE LONDON", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "CONSIGLIO NAZIONALE DELLE RICERCHE", "INSTITUTO NACIONAL DE TECNICA AEROESPACIAL ESTEBAN TERRADAS", "A.D.S. INTERNATIONAL SRL", "ARCOPTIX SA", "ANDOR TECHNOLOGY LIMITED"], "EU_Contribution": ["EUR 2 977 273"], "Project_Title": ["Getting Ready for EST"], "Total_Cost": ["EUR 3 956 730"], "Country": ["Spain", "Italy", "Italy", "Germany", "Sweden", "United Kingdom", "United Kingdom", "Spain", "Italy", "Spain", "Italy", "Switzerland", "United Kingdom"], "Project_ACR": ["GREST"], "Technology_Description": "The present project is intended to take the European Solar Telescope (EST) to the next level of development by undertaking crucial activities to improve the performance of current state-of-the-art instrumentation. Legal, industrial and socio-economic issues will also be addressed, as key questions for the attainment of EST. The particular developments and strategic tasks proposed here can be summarised in the following specific objectives:", "To": ["2018-05-31, ongoing project"], "Meta": [""], "Topic_s": ["INFRADEV-1-2014 - Design studies"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-06-01"], "Project_ID": ["653982"], "Call_for_Proposal": ["H2020-INFRADEV-1-2014-1"]}, -{"Partners": ["HAROKOPIO UNIVERSITY", "QUEEN MARY UNIVERSITY OF LONDON", "INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE", "CONSIGLIO NAZIONALE DELLE RICERCHE", "FUNDACION PARA EL FOMENTO DE LA INVESTIGACION SANITARIA Y BIOMEDICA DE LA COMUNITAT VALENCIANA", "BIOTECH VANA SL", "Randox Laboratories Ltd", "MARASCIO FERNANDO", "SANOFI-AVENTIS DEUTSCHLAND GMBH", "ENOSIS MASTICHOPARAGOGON CHIOU", "PERSPECTUM DIAGNOSTICS LTD", "Univerzitet u Novom Sadu - Medicinski fakultet", "UNIVERZITET U ISTOCNOM SARAJEVU"], "EU_Contribution": ["EUR 2 124 000"], "Project_Title": ["Mastiha treatment for healthy obese with NAFLD diagnosis (MAST4HEALTH)."], "Total_Cost": ["EUR 2 124 000"], "Country": ["Greece", "United Kingdom", "France", "Italy", "Spain", "Spain", "United Kingdom", "Italy", "Germany", "Greece", "United Kingdom", "Serbia", "Bosnia and Herzegovina"], "Project_ACR": ["MAST4HEALTH"], "Technology_Description": "MAST4HEALTH is set on the concept of a multidisciplinary approach to assess a non-pharmacological intervention for managing NAFLD/NASH, one of the most common complications of obesity and diabetes mellitus in Western populations affecting approximately 50% of diabetics and 76% of obese patients. Because of limitations in current NAFLD treatment therapies, many new efforts focus on exploring non-pharmacologic means for managing the disease and in particular through dietary substances or bioactive phytochemicals in fruits, vegetables, and plants or their products. MAST4HEALTH aims at exploring the effect of Mastiha, a natural product of Greece which was recently shown to possess antioxidant/anti-inflammatory and lipid lowering properties. We designed a multicenter randomized double blind placebo controlled (parallel arm) clinical trial to test the effectiveness of Mastiha supplement as new non-pharmacologic strategy for NAFLD/NASH treatment. MAST4HEALTH will explore gene-diet interactions, more specifically the potential personalized activity of the Mastiha, and correlate genetic and epigenetic markers with metabolomic and intestinal microbiota profiles pre- and post-intervention. The effectiveness of the proposed intervention will be evaluated via clinical and laboratory markers of the disease. To this end, MAST4HEALTH will train a number of researchers and PhD students in multidisciplinary approaches of this survey. MAST4HEALTH is expected to build and enhance cooperation among partners meanwhile strengthening the interaction between our academic and non-academic sectors", "To": ["2020-02-29, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Greece"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["691042"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA", "BCAM - BASQUE CENTER FOR APPLIED MATHEMATICS", "INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE", "BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION", "TOTAL S.A."], "EU_Contribution": ["EUR 580 500"], "Project_Title": ["Geophysical Exploration using Advanced GAlerkin Methods"], "Total_Cost": ["EUR 580 500"], "Country": ["Spain", "Spain", "France", "Spain", "France"], "Project_ACR": ["GEAGAM"], "Technology_Description": "The main objective of this Marie Curie RISE action is to improve and exchange interdisciplinary knowledge on applied mathematics, high performance computing, and geophysics to be able to better simulate and understand the materials composing the Earth's subsurface. This is essential for a variety of applications such as CO2 storage, hydrocarbon extraction, mining, and geothermal energy production, among others. All these problems have in common the need to obtain an accurate characterization of the Earth's subsurface, and to achieve this goal, several complementary areas will be studied, including the mathematical foundations of various high-order Galerkin multiphysics simulation methods, the efficient computer implementation of these methods in large parallel machines and GPUs, and some crucial geophysical aspects such as the design of measurement acquisition systems in different scenarios. ", "To": ["2017-12-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["644202"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["Teknologian tutkimuskeskus VTT Oy", "AALTO-KORKEAKOULUSAATIO", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.", "RISE PROCESSUM AB", "KUNGLIGA TEKNISKA HOEGSKOLAN", "STIFTELSEN SINTEF", "INSTITUT TECHNOLOGIQUE FCBA (FORETCELLULOSE BOIS-CONSTRUCTION AMEUBLEMENT)", "INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE", "FUNDACION TECNALIA RESEARCH & INNOVATION", "KOMPETENZZENTRUM HOLZ GMBH", "LATVIJAS VALSTS KOKSNES KIMIJAS INSTITUTS", "INSTITUTUL DE CHIMIE MACROMOLECULARA PETRU PONI", "BIO BASE EUROPE PILOT PLANT VZW"], "EU_Contribution": ["EUR 2 628 700"], "Project_Title": ["Research Infrastructure for Circular Forest Bioeconomy"], "Total_Cost": ["EUR 2 630 950"], "Country": ["Finland", "Finland", "Germany", "Sweden", "Sweden", "Norway", "France", "France", "Spain", "Austria", "Latvia", "Romania", "Belgium"], "Project_ACR": ["ERIFORE"], "Technology_Description": "The ERIFORE will realize the European potential to consolidate its place as a world leader in biomass based research and innovations. ERIFORE builds on a new firm alliance aiming to establish open access distributed forest bioeconomy research infrastructure across Europe enabling scientific discoveries to be transferred to new business models, novel products and services enabling sustainable growth. The research infrastructure will focus on topics supporting Circular Forest Bioeconomy concepts starting from fundamental teaching and knowledge sharing to high level research laboratories and large scale piloting facilities.", "To": ["2018-01-31, closed project"], "Meta": [""], "Topic_s": ["INFRADEV-1-2014 - Design studies"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Finland"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Other", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Other"], "From": ["2016-01-01"], "Project_ID": ["654371"], "Call_for_Proposal": ["H2020-INFRADEV-1-2014-1"]}, -{"Partners": ["FONDATION EUROPEENNE DE LA SCIENCE", "AGENZIA PER LA PROMOZIONE DELLA RICERCA EUROPEA", "ETHNIKO IDRYMA EREVNON"], "EU_Contribution": ["EUR 1 951 092"], "Project_Title": ["MERIL-2 MAPPING OF THE EUROPEAN RESEARCH INFRASTRUCTURE LANDSCAPE"], "Total_Cost": ["EUR 1 951 092"], "Country": ["France", "Italy", "Greece"], "Project_ACR": ["MERIL-2"], "Technology_Description": "The MERIL-2 project aims to create an authoritative, exhaustive online source of scientific and policy relevant data on European research infrastructures (RIs) of more than national relevance. It addresses the work programme priorities of promoting the development and coordination of policy and international cooperation in the domain of RIs. MERIL-2 builds on the successful development of the original MERIL and research mapping exercise initiated by the ESF membership and which services ESFRI. MERIL-2 aims to achieve step changes in terms of: 1) The comprehensiveness of RIs identified in the portal from 900 to 1200+ and the full publication of those identified from 500 to 800; 2) The utility of the portal in terms of functionalities, analytical capacity and intermediation; 3) Stakeholder value in terms of policy relevant data including financial and human resource dimensions and coverage of RI mapping processes and tools in comparator regions. These objectives will be met through a synergistic partnership of three organisations; European Science Foundation (ESF), the Greek National Documentation Centre (EKT-NHRF) and Agency for the Promotion of Research (APRE), that harnesses the complementary strengths of advanced portal design, European member state communication systems and deep knowledge of the RI landscape and data acquisition requirements under the leadership of an expert advisory committee. On a practical level, the approach will include redesign of the portal with enhanced functionalities, expert/ESFRI and NDI consultations on policy data needs and parameters, a complementary review of RI data policies and strategies and policies including implications of policy data provision and resourcing a publishing completion function for non-responsive RIs. These actions will lead to an enhanced MERIL-2 portal with comprehensive coverage of the European RI landscape and high quality systems and data of stakeholder interest with flexible, open and user oriented interfaces.", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["INFRASUPP-5-2014 - Policy measures for research infrastructures"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["France"], "Activity": ["Other", "Research Organisations", "Research Organisations"], "From": ["2016-03-01"], "Project_ID": ["654296"], "Call_for_Proposal": ["H2020-INFRASUPP-2014-2"]}, -{"Partners": ["THE UNIVERSITY OF SUSSEX", "UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6", "RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN", "UNIVERSITA DEGLI STUDI DI CATANIA", "FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS", "UNIVERSITA DEGLI STUDI DELL'AQUILA", "UNIVERSIDAD DE MALAGA", "UNIVERSITETET I OSLO"], "EU_Contribution": ["EUR 3 918 484,14"], "Project_Title": ["Modelling and Computation of Shocks and Interfaces"], "Total_Cost": ["EUR 3 918 484,14"], "Country": ["United Kingdom", "France", "Germany", "Italy", "Greece", "Italy", "Spain", "Norway"], "Project_ACR": ["ModCompShock"], "Technology_Description": "The proposed ITN entitled \"Modelling and computation of Shocks and Interfaces\" will focus on the training of young researchers in the general area of nonlinear hyperbolic and convection dominated PDEs with emphasis on innovative modelling and computational methods.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["642768"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["UNIVERSIDADE DO PORTO", "UNIVERSITA DEGLI STUDI DI MILANO", "NATIONAL UNIVERSITY OF IRELAND GALWAY", "UNIVERSITA DEGLI STUDI DI PERUGIA"], "EU_Contribution": ["EUR 720 000"], "Project_Title": ["Sexual Plant Reproduction \u2013 Seed formation"], "Total_Cost": ["EUR 751 500"], "Country": ["Portugal", "Italy", "Ireland", "Italy"], "Project_ACR": ["SexSeed"], "Technology_Description": "By 2050, it is estimated that the human population will reach 9 billion. To feed this growing population, it will be necessary to at least double agricultural yields, without increasing the amount of arable land. ", "To": ["2020-02-29, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Portugal"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["690946"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["NATURAL ENVIRONMENT RESEARCH COUNCIL", "MARIENE INFORMATIE SERVICE MARIS BV", "ISTITUTO NAZIONALE DI OCEANOGRAFIA E DI GEOFISICA SPERIMENTALE", "INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER", "HELLENIC CENTRE FOR MARINE RESEARCH", "AGENZIA NAZIONALE PER LE NUOVE TECNOLOGIE, L'ENERGIA E LO SVILUPPO ECONOMICO SOSTENIBILE", "UNIVERSITE DE LIEGE", "CONSIGLIO NAZIONALE DELLE RICERCHE", "INSTITUT ROYAL DES SCIENCES NATURELLES DE BELGIQUE", "NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO", "ALFRED-WEGENER-INSTITUT HELMHOLTZ-ZENTRUM FUR POLAR- UND MEERESFORSCHUNG", "BUNDESAMT FUR SEESCHIFFFAHRT UND HYDROGRAPHIE", "ALL-RUSSIAN RESEARCH INSTITUTE OF HYDROMETEOROLOGICAL INFORMATION-WORLD DATA CENTRE", "VLAAMS INSTITUUT VOOR DE ZEE VZW", "UNIVERSITAET BREMEN", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "52\u00b0North Initiative for Geospatial Open Source Software GmbH", "IEEE FRANCE SECTION", "SOCIB - CONSORCIO PARA EL DISENO, CONSTRUCCION, EQUIPAMIENTO Y EXPLOTACION DEL SISTEMA DE OBSERVACION COSTERO DE LAS ILLES BALEARS"], "EU_Contribution": ["EUR 1 912 086,25"], "Project_Title": ["Extending the Ocean Data Interoperability Platform"], "Total_Cost": ["EUR 1 912 086,25"], "Country": ["United Kingdom", "Netherlands", "Italy", "France", "Greece", "Italy", "Belgium", "Italy", "Belgium", "Netherlands", "Germany", "Germany", "Russia", "Belgium", "Germany", "Spain", "Germany", "France", "Spain"], "Project_ACR": ["ODIP 2"], "Technology_Description": "The Ocean Data Interoperability Platform project is promoting the development of a common global framework for marine data management by developing interoperability between existing regional e-infrastructures. Through a series of international workshops attracting relevant domain experts a number of prototype interoperability solutions will be developed which will be implemented by the regional data infrastructures to provide users with open access to good quality multidisciplinary data and associated services. Improved access to a range of marine data will facilitate re-use of the data and support researchers in addressing grand challenges such as climate change and conservation of marine resources.", "To": ["2018-03-31, ongoing project"], "Meta": [""], "Topic_s": ["INFRASUPP-6-2014 - International cooperation for research infrastructures"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Other", "Other", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2015-04-01"], "Project_ID": ["654310"], "Call_for_Proposal": ["H2020-INFRASUPP-2014-2"]}, -{"Partners": ["UNIVERSITE D'AIX MARSEILLE", "BERNHARD-NOCHT-INSTITUT FUER TROPENMEDIZIN", "THE SECRETARY OF STATE FOR ENVIRONMENT, FOOD AND RURAL AFFAIRS", "UNIVERSITAETSKLINIKUM BONN", "Department of Health", "UNIVERSITAET BASEL", "UNIVERZA V LJUBLJANI", "BIOMEDICINSKE CENTRUM SLOVENSKEJ AKADEMIE VIED", "VIROLOGICKY USTAV SLOVENSKEJ AKADEMIE VIED", "ISTITUTO NAZIONALE PER LE MALATTIE INFETTIVE LAZZARO SPALLANZANI-ISTITUTO DI RICOVERO E CURA A CARATTERE SCIENTIFICO", "ROBERT KOCH-INSTITUT", "ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM", "ACADEMISCH ZIEKENHUIS LEIDEN", "INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE", "INSTITUT PASTEUR", "FRIEDRICH LOEFFLER INSTITUT - BUNDESFORSCHUNGSINSTITUT FUER TIERGESUNDHEIT", "THE PIRBRIGHT INSTITUTE LBG", "AGRICULTURAL RESEARCH COUNCIL (ARC)", "NATIONAL HEALTH LABORATORY SERVICES", "FEDERAL STATE BUDGETARY SCIENTIFIC INSTITUTION CHUMAKOV INSTITUTE OF POLIOMYELITIS AND VIRAL ENCEPHALITIDES", "SCIENTIFIC RESEARCH INSTITUTE OF INFLUENZA OF THE MINISTRY OF HEALTHCARE AND SOCIAL DEVELOPMENT OF THE RUSSIAN FEDERATION", "RESEARCH INSTITUTE OF VACCINES AND SERA II MECHNIKOV", "WUHAN INSTITUTE OF VIROLOGY, CHINESE ACADEMY OF SCIENCES", "COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION", "Folkh\u00e4lsomyndigheten (The Public Health Agency of Sweden)", "FONDATION MERIEUX"], "EU_Contribution": ["EUR 10 792 868"], "Project_Title": ["European Virus Archive goes global"], "Total_Cost": ["EUR 12 168 054,68"], "Country": ["France", "Germany", "United Kingdom", "Germany", "United Kingdom", "Switzerland", "Slovenia", "Slovakia", "Slovakia", "Italy", "Germany", "Netherlands", "Netherlands", "France", "France", "Germany", "United Kingdom", "South Africa", "South Africa", "Russia", "Russia", "Russia", "China", "Australia", "Sweden", "France"], "Project_ACR": ["EVAg"], "Technology_Description": "The overall objective will be to create and mobilise an International network of high calibre centres around a strong European group of institutes selected for their appropriate expertises, to collect, amplify, characterise, standardise, authenticate, distribute and track, mammalian and other exotic viruses. The network of EVAg laboratories including 25 institutions represents an extensive range of virological disciplines. The architecture of the consortium is based on the association of capacities accessible to the partners but also to any end-users through the EVAg web-based catalogue. This concept has been elaborated and tested for its efficiency during the successful EVA project (FP7). The project will integrate more facilities dedicated to high risk pathogen (HRP) manipulation (1 in EVA, 13 in EVAg) The access to products derived from those HRP will be enhanced and for instance the production of diagnostic reagents will be facilitated. The new project will also provide access to high containment biosafety facilities to carry out in vivo studies of infectious disease using natural or models hosts, to look at prophylactic or therapeutic control measures and to develop materials for the evaluation of diagnostic tests, meaning an extensive capacity to service and to training. EVAg will also link up with other network-based virus-associated programmes that exist globally. However, looking further ahead, EVAg is conceived ultimately to be an open entity aiming at developing synergies and complementarity capabilities in such a way as to offer an improved access to researchers. This project will generate the largest collection of mammalian viruses in the world and move beyond the current state-of-the-art to provide an increasingly valuable resource and service to the world\u2019s scientific community, including government health departments, higher education institutes, industry and, through information systems, the general public.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["INFRAIA-1-2014-2015 - Integrating and opening existing national and regional research infrastructures of European interest"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations"], "From": ["2015-04-01"], "Project_ID": ["653316"], "Call_for_Proposal": ["H2020-INFRAIA-2014-2015"]}, -{"Partners": ["INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE", "HAVFORSKNINGSINSTITUTTET", "THE UNIVERSITY OF STIRLING", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "HELLENIC CENTRE FOR MARINE RESEARCH", "Nemzeti Agrarkutatasi es Innovacios Kozpont", "INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER", "NOFIMA AS", "JIHOCESKA UNIVERZITA V CESKYCH BUDEJOVICICH", "NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU", "SINTEF FISKERI OG HAVBRUK AS", "SINTEF OCEAN AS", "UNIVERSIDAD DE LAS PALMAS DE GRAN CANARIA", "WAGENINGEN UNIVERSITY", "UNIVERSITEIT GENT", "STICHTING WAGENINGEN RESEARCH", "AquaTT UETP Ltd", "INRA TRANSFERT S.A.", "UNIVERSITE DE LORRAINE", "DANMARKS TEKNISKE UNIVERSITET", "CENTRO DE CIENCIAS DO MAR DO ALGARVE", "INSTITUTO ESPANOL DE OCEANOGRAFIA", "European Aquaculture Technology and Innovation Platform"], "EU_Contribution": ["EUR 9 708 867"], "Project_Title": ["AQUAculture infrastructures for EXCELlence in European fish research towards 2020"], "Total_Cost": ["EUR 9 708 867"], "Country": ["France", "Norway", "United Kingdom", "Spain", "Greece", "Hungary", "France", "Norway", "Czech Republic", "Norway", "Norway", "Norway", "Spain", "Netherlands", "Belgium", "Netherlands", "Ireland", "France", "France", "Denmark", "Portugal", "Spain", "Belgium"], "Project_ACR": ["AQUAEXCEL2020"], "Technology_Description": "AQUAEXCEL2020 aims to integrate top class European aquaculture research facilities of very diverse nature, covering all relevant scientific fields for research and innovation in aquaculture, from genetics to technology through pathology, physiology and nutrition. It will put in place a user-friendly one-stop access to high-quality services and resources from 39 installations covering both established and new aquaculture species, all types of experimental systems as well as sequencing facilities. Giving a prominent place to EU aquaculture industry research needs through a strong involvement of the European Aquaculture Technology and Innovation Platform, it will enable excellent research and sustainable innovation to both public and private sector. It will benefit from the support of the ESFRI infrastructures EMBRC (Marine Biology) and ELIXIR (Life Sciences data) and bring aquaculture research specificities to their agendas.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["INFRAIA-1-2014-2015 - Integrating and opening existing national and regional research infrastructures of European interest"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Other"], "From": ["2015-10-01"], "Project_ID": ["652831"], "Call_for_Proposal": ["H2020-INFRAIA-2014-2015"]}, -{"Partners": ["EUROPEAN MOLECULAR BIOLOGY LABORATORY", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "EARLHAM INSTITUTE", "THE UNIVERSITY OF MANCHESTER", "TARTU ULIKOOL", "Stichting Netherlands Bioinformatics Centre", "FUNDACION CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III", "FUNDACIO CENTRE DE REGULACIO GENOMICA", "FUNDACION DE LA COMUNIDAD VALENCIANA CENTRO DE INVESTIGACION PRINCIPEFELIPE", "FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)", "UNIVERSIDAD DE MALAGA", "BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "UNIVERSIDAD POMPEU FABRA", "FUNDACIO INSTITUT MAR D INVESTIGACIONS MEDIQUES IMIM", "FUNDACAO CALOUSTE GULBENKIAN", "INESC ID - INSTITUTO DE ENGENHARIADE SISTEMAS E COMPUTADORES, INVESTIGACAO E DESENVOLVIMENTO EM LISBOA", "INSTITUTO DE BIOLOGIA EXPERIMENTAL E TECNOLOGICA", "CENTRO DE CIENCIAS DO MAR DO ALGARVE", "CSC-TIETEEN TIETOTEKNIIKAN KESKUS OY", "UNIVERSITETET I BERGEN", "NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU", "UNIVERSITETET I TROMSOE", "UNIVERSITETET I OSLO", "SWISS INSTITUTE OF BIOINFORMATICS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE", "CENTRE DE COOPERATION INTERNATIONALE EN RECHERCHE AGRONOMIQUE POUR LEDEVELOPPEMENT - C.I.R.A.D. EPIC", "INSTITUT PASTEUR", "CONSIGLIO NAZIONALE DELLE RICERCHE", "LINKOPINGS UNIVERSITET", "UNIVERZA V LJUBLJANI", "NACIONALNI INSTITUT ZA BIOLOGIJO", "USTAV ORGANICKE CHEMIE A BIOCHEMIE, AV CR, V.V.I.", "Masarykova univerzita", "CESNET ZAJMOVE SDRUZENI PRAVNICKYCH OSOB", "VIB", "DANMARKS TEKNISKE UNIVERSITET", "BIOMEDICAL SCIENCES RESEARCH CENTER ALEXANDER FLEMING", "THE HEBREW UNIVERSITY OF JERUSALEM", "ATHINA-EREVNITIKO KENTRO KAINOTOMIAS STIS TECHNOLOGIES TIS PLIROFOFORIAS, TON EPIKOLNONION KAI TIS GNOSIS", "FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS", "THE UNIVERSITY OF EDINBURGH", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 19 051 482"], "Project_Title": ["ELIXIR-EXCELERATE: Fast-track ELIXIR implementation and drive early user exploitation across the life-sciences."], "Total_Cost": ["EUR 19 051 482"], "Country": ["Germany", "United Kingdom", "United Kingdom", "United Kingdom", "Estonia", "Netherlands", "Spain", "Spain", "Spain", "Spain", "Spain", "Spain", "Spain", "Spain", "Spain", "Portugal", "Portugal", "Portugal", "Portugal", "Finland", "Norway", "Norway", "Norway", "Norway", "Switzerland", "France", "France", "France", "France", "Italy", "Sweden", "Slovenia", "Slovenia", "Czech Republic", "Czech Republic", "Czech Republic", "Belgium", "Denmark", "Greece", "Israel", "Greece", "Greece", "United Kingdom", "United Kingdom"], "Project_ACR": ["ELIXIR-EXCELERATE"], "Technology_Description": "The life sciences are undergoing a transformation. Modern experimental tools study the molecules, reactions, and organisation of life in unprecedented detail. The precipitous drop in costs for high-throughput biology has enabled European research laboratories to produce an ever-increasing amount of data. Life scientists are rapidly generating the most complex and heterogeneous datasets that science can currently imagine, with unprecedented volumes of biological data to manage.", "To": ["2019-08-31, ongoing project |"], "Meta": [""], "Topic_s": ["INFRADEV-3-2015 - Individual implementation and operation of ESFRI projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Germany"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Other", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["676559"], "Call_for_Proposal": ["H2020-INFRADEV-1-2015-1"]}, -{"Partners": ["CONSIGLIO NAZIONALE DELLE RICERCHE", "Koninklijk Instituut voor het Kunstpatrimonium", "Doerner Institut, Bayerische Staatsgem\u00e4ldesammlungen", "STIFTUNG PREUSSISCHER KULTURBESITZ", "RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN", "STATENS MUSEUM FOR KUNST", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "Museo Nacional del Prado", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE", "Soci\u00e9t\u00e9 civile SYNCHROTRON SOLEIL", "FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS", "IDRYMA ORMYLIA", "Magyar Tudomanyos Akademia Atommagkutato Intezete", "MAGYAR TUDOMANYOS AKADEMIA WIGNER FIZIKAI KUTATOKOZPONT", "AGENZIA PER LA PROMOZIONE DELLA RICERCA EUROPEA", "OPIFICIO DELLE PIETRE DURE", "ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA", "MINISTERIE VAN ONDERWIJS, CULTUUR EN WETENSCHAP", "UNIWERSYTET MIKOLAJA KOPERNIKA W TORUNIU", "LABORATORIO NACIONAL DE ENGENHARIA CIVIL", "BRITISH MUSEUM", "THE NATIONAL GALLERY", "THE J. PAUL GETTY TRUST"], "EU_Contribution": ["EUR 7 994 987,73"], "Project_Title": ["Integrated Platform for the European Research Infrastructure ON Cultural Heritage"], "Total_Cost": ["EUR 8 157 487,73"], "Country": ["Italy", "Belgium", "Germany", "Germany", "Germany", "Denmark", "Spain", "Spain", "France", "France", "France", "Greece", "Greece", "Hungary", "Hungary", "Italy", "Italy", "Italy", "Netherlands", "Poland", "Portugal", "United Kingdom", "United Kingdom", "United States"], "Project_ACR": ["IPERION CH"], "Technology_Description": "IPERION CH aims to establish the unique pan-European research infrastructure in Heritage Science by integrating national world-class facilities at research centres, universities and museums. The cross-disciplinary consortium of 23 partners (from 12 Member States and the US) offers access to instruments, methodologies and data for advancing knowledge and innovation in the conservation and restoration of cultural heritage. Fourth in a line of successful projects (CHARISMA-FP7, Eu-ARTECH-FP6 and LabS-TECH network-FP5), IPERION CH widens trans-national access by adding new providers with new expertise and instruments to the three existing complementary platforms ARCHLAB, FIXLAB and MOLAB. ", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["INFRAIA-1-2014-2015 - Integrating and opening existing national and regional research infrastructures of European interest"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Other"], "From": ["2015-05-01"], "Project_ID": ["654028"], "Call_for_Proposal": ["H2020-INFRAIA-2014-2015"]}, -{"Partners": ["CSC-TIETEEN TIETOTEKNIIKAN KESKUS OY", "BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION", "CENTRE EUROPEEN DE RECHERCHE ET DE FORMATION AVANCEE EN CALCUL SCIENTIFIQUE", "CINECA CONSORZIO INTERUNIVERSITARIO", "CINES", "DEUTSCHES KLIMARECHENZENTRUM GMBH", "UMWELTBUNDESAMT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (UBA GMBH)", "EBERHARD KARLS UNIVERSITAET TUEBINGEN", "THE UNIVERSITY OF EDINBURGH", "ISTITUTO NAZIONALE DI GEOFISICA E VULCANOLOGIA", "FORSCHUNGSZENTRUM JULICH GMBH", "INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK", "SURFSARA BV", "UNINETT SIGMA AS", "UNINETT SIGMA2 AS", "SCIENCE AND TECHNOLOGY FACILITIES COUNCIL", "UNIVERSITY COLLEGE LONDON", "TRUST-IT SERVICES LIMITED", "ETHNIKO DIKTYO EREVNAS TECHNOLOGIAS AE", "KARLSRUHER INSTITUT FUER TECHNOLOGIE", "STICHTING LIBER", "KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW", "E-SCIENCE DATA FACTORY", "LUNDS UNIVERSITET", "KONINKLIJK NEDERLANDS METEOROLOGISCH INSTITUUT-KNMI", "HELMHOLTZ ZENTRUM POTSDAM DEUTSCHESGEOFORSCHUNGSZENTRUM GFZ", "CLARIN ERIC", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "JISC LBG", "UNIVERZITET U NOVOM SADU", "EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH", "HELSINGIN YLIOPISTO", "EUROPEAN MOLECULAR BIOLOGY LABORATORY", "UPPSALA UNIVERSITET", "BIOSENSE INSTITUTE - RESEARCH AND DEVELOPMENT INSTITUTE FOR INFORMATION TECHNOLOGIES IN BIOSYSTEMS", "UNITED KINGDOM ATOMIC ENERGY AUTHORITY"], "EU_Contribution": ["EUR 18 865 385"], "Project_Title": ["EUDAT2020"], "Total_Cost": ["EUR 19 052 882"], "Country": ["Finland", "Spain", "France", "Italy", "France", "Germany", "Austria", "Germany", "United Kingdom", "Italy", "Germany", "Poland", "Netherlands", "Norway", "Norway", "United Kingdom", "United Kingdom", "United Kingdom", "Greece", "Germany", "Netherlands", "Netherlands", "France", "Sweden", "Netherlands", "Germany", "Netherlands", "Germany", "United Kingdom", "Serbia", "Switzerland", "Finland", "Germany", "Sweden", "Serbia", "United Kingdom"], "Project_ACR": ["EUDAT2020"], "Technology_Description": "EUDAT2020 brings together a unique consortium of e-infrastructure providers, research infrastructure operators, and researchers from a wide range of scientific disciplines under several of the ESFRI themes, working together to address the new data challenge. ", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["EINFRA-1-2014 - Managing, preserving and computing with big research data"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Finland"], "Activity": ["Other", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Other", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Other", "Research Organisations", "Research Organisations", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Other", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations"], "From": ["2015-03-01"], "Project_ID": ["654065"], "Call_for_Proposal": ["H2020-EINFRA-2014-2"]}, -{"Partners": ["FORSCHUNGSZENTRUM JULICH GMBH", "Gauss Centre for Supercomputing (GCS) e.V.", "GRAND EQUIPEMENT NATIONAL DE CALCUL INTENSIF", "THE UNIVERSITY OF EDINBURGH", "BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION", "CSC-TIETEEN TIETOTEKNIIKAN KESKUS OY", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "SURFSARA BV", "UNIVERSITAT LINZ", "UPPSALA UNIVERSITET", "CINECA CONSORZIO INTERUNIVERSITARIO", "INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK", "UNINETT SIGMA2 AS", "ETHNIKO DIKTYO EREVNAS TECHNOLOGIAS AE", "UNIVERSIDADE DE COIMBRA", "NATIONAL UNIVERSITY OF IRELAND GALWAY", "ISTANBUL TEKNIK UNIVERSITESI", "THE CYPRUS RESEARCH AND EDUCATIONAL FOUNDATION", "\"ASSOCIATION \"\"NATIONAL CENTRE FOR SUPERCOMPUTING APPLICATIONS\"", "VYSOKA SKOLA BANSKA - TECHNICKA UNIVERZITA OSTRAVA", "NEMZETI INFORMACIOS INFRASTRUKTURA FEJLESZTESI IRODA", "KORMANYZATI INFORMATIKAI FEJLESZTESI UGYNOKSEG", "KOBENHAVNS UNIVERSITET", "MACHBA - INTERUNIVERSITY COMPUTATION CENTER", "PARTNERSHIP FOR ADVANCED COMPUTINGIN EUROPE AISBL", "UNIVERZA V LJUBLJANI", "VYPOCTOVE STREDISKO SLOVENSKEJ AKADEMIE VIED"], "EU_Contribution": ["EUR 15 000 000"], "Project_Title": ["PRACE 4th Implementation Phase Project"], "Total_Cost": ["EUR 16 354 408,25"], "Country": ["Germany", "Germany", "France", "United Kingdom", "Spain", "Finland", "Switzerland", "Netherlands", "Austria", "Sweden", "Italy", "Poland", "Norway", "Greece", "Portugal", "Ireland", "Turkey", "Cyprus", "Bulgaria", "Czech Republic", "Hungary", "Hungary", "Denmark", "Israel", "Belgium", "Slovenia", "Slovakia"], "Project_ACR": ["PRACE-4IP"], "Technology_Description": "PRACE, the Partnership for Advanced Computing, was established in May 2010 as a permanent pan-European High Performance Computing service providing world-class systems for world-class science. Six systems at the highest performance level (Tier-0) are deployed by Germany, France, Italy and Spain providing researchers with over 9 billion core hours of compute time. HPC experts from twenty-five member states - funded in part in three implementation projects - enabled users from academia and industry to ascertain leadership and remain competitive in the Global Race. Currently PRACE is preparing for PRACE 2.0, the successor of the initial five year period. ", "To": ["2017-12-31, closed project"], "Meta": [""], "Topic_s": ["EINFRA-4-2014 - Pan-European High Performance Computing infrastructure and services"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations", "Other", "Higher or Secondary Education Establishments", "Research Organisations", "Other", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Other", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2015-02-01"], "Project_ID": ["653838"], "Call_for_Proposal": ["H2020-EINFRA-2014-2"]}, -{"Partners": ["DEUTSCHES KLIMARECHENZENTRUM GMBH", "EUROPEAN CENTRE FOR MEDIUM-RANGE WEATHER FORECASTS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "CENTRE EUROPEEN DE RECHERCHE ET DE FORMATION AVANCEE EN CALCUL SCIENTIFIQUE", "BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION", "SCIENCE AND TECHNOLOGY FACILITIES COUNCIL", "MET OFFICE", "THE UNIVERSITY OF READING", "SVERIGES METEOROLOGISKA OCH HYDROLOGISKA INSTITUT", "NATIONAL UNIVERSITY OF IRELAND GALWAY", "FONDAZIONE CENTRO EURO-MEDITERRANEO SUI CAMBIAMENTI CLIMATICI", "DEUTSCHER WETTERDIENST", "SEAGATE SYSTEMS UK LIMITED", "BULL SAS", "ALLINEA SOFTWARE LIMITED"], "EU_Contribution": ["EUR 4 951 048,75"], "Project_Title": ["Excellence in SImulation of Weather and Climate in Europe"], "Total_Cost": ["EUR 4 951 048,75"], "Country": ["Germany", "United Kingdom", "France", "Germany", "France", "Spain", "United Kingdom", "United Kingdom", "United Kingdom", "Sweden", "Ireland", "Italy", "Germany", "United Kingdom", "France", "United Kingdom"], "Project_ACR": ["ESiWACE"], "Technology_Description": "ESiWACE will substantially improve efficiency and productivity of numerical weather and climate simulation on high-performance computing platforms by supporting the end-to-end workflow of global Earth system modelling in HPC environment. This will be obtained by improving and supporting (1) scalability of models, tools and data management on state-of-the-art supercomputer systems (2) Usability of models and tools throughout the European HPC eco-system, and (3) the Exploitability of the huge amount of resulting data.", "To": ["2019-08-31, ongoing project |"], "Meta": [""], "Topic_s": ["EINFRA-5-2015 - Centres of Excellence for computing applications"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-09-01"], "Project_ID": ["675191"], "Call_for_Proposal": ["H2020-EINFRA-2015-1"]}, -{"Partners": ["ARCTUR RACUNALNISKI INZENIRING DOO", "NATIONAL UNIVERSITY OF IRELAND GALWAY", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.", "INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK", "ETHNIKO DIKTYO EREVNAS TECHNOLOGIAS AE", "FUNDACION PUBLICA GALLEGA CENTRO TECNOLOGICO DE SUPERCOMPUTACION DE GALICIA", "VYSOKA SKOLA BANSKA - TECHNICKA UNIVERZITA OSTRAVA", "YOTTA ADVANCED COMPUTING DOO ZA ISTRAZIVANJE I USLUGE", "UNIVERSITATEA DE VEST DIN TIMISOARA", "INSTITUTE OF INFORMATION AND COMMUNICATION TECHNOLOGIES", "RUDER BOSKOVIC INSTITUTE", "HERCULESSTICHTING", "FONDS VOOR WETENSCHAPPELIJK ONDERZOEK-VLAANDEREN", "VILNIAUS UNIVERSITETAS", "MEO-SERVICOS DE COMUNICACOES E MULTIMEDIA SA", "HIGH PERFORMANCE COMPUTING WALES", "BANGOR UNIVERSITY"], "EU_Contribution": ["EUR 1 998 363,75"], "Project_Title": ["Supercomputing Expertise for SmAll and Medium Enterprise Network"], "Total_Cost": ["EUR 1 998 363,75"], "Country": ["Slovenia", "Ireland", "Germany", "Poland", "Greece", "Spain", "Czech Republic", "Croatia", "Romania", "Bulgaria", "Croatia", "Belgium", "Belgium", "Lithuania", "Portugal", "United Kingdom", "United Kingdom"], "Project_ACR": ["SESAME NET"], "Technology_Description": "Network of HPC Competence Centres for SMEs", "To": ["2017-05-31, closed project"], "Meta": [""], "Topic_s": ["EINFRA-6-2014 - Network of HPC Competence Centres for SMEs"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Slovenia"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Other", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Higher or Secondary Education Establishments"], "From": ["2015-06-01"], "Project_ID": ["654416"], "Call_for_Proposal": ["H2020-EINFRA-2014-2"]}, -{"Partners": ["UNIVERSITEIT UTRECHT", "EUROPEAN MOLECULAR BIOLOGY LABORATORY", "DIAMOND LIGHT SOURCE LIMITED", "CONSORZIO INTERUNIVERSITARIO RISONANZE MAGNETICHE DI METALLO PROTEINE", "JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN", "STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS", "Masarykova univerzita", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "FORSCHUNGSVERBUND BERLIN EV", "Soci\u00e9t\u00e9 civile SYNCHROTRON SOLEIL", "LUNDS UNIVERSITET", "UNIVERSITEIT LEIDEN", "ACADEMISCH ZIEKENHUIS LEIDEN", "INSTALLATION EUROPEENNE DE RAYONNEMENT SYNCHROTRON", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "INSTRUCT ACADEMIC SERVICES LIMITED", "AARHUS UNIVERSITET", "EUROPEAN SPALLATION SOURCE ERIC", "EUROPEAN SPALLATION SOURCE ESS AB", "EOTVOS LORAND TUDOMANYEGYETEM", "UNIVERSIDADE NOVA DE LISBOA", "INSTITUTO DE TECNOLOGIA QUIMICA E BIOLOGICA - UNIVERSIDADE NOVA DE LISBOA", "OULUN YLIOPISTO", "PANEPISTIMIO PATRON", "WEIZMANN INSTITUTE OF SCIENCE"], "EU_Contribution": ["EUR 9 999 534,25"], "Project_Title": ["Infrastructure for NMR, EM and X-rays for translational research"], "Total_Cost": ["EUR 9 999 534,25"], "Country": ["Netherlands", "Germany", "United Kingdom", "Italy", "Germany", "Netherlands", "Czech Republic", "Spain", "Germany", "France", "Sweden", "Netherlands", "Netherlands", "France", "France", "United Kingdom", "Denmark", "Sweden", "Sweden", "Hungary", "Portugal", "Portugal", "Finland", "Greece", "Israel"], "Project_ACR": ["iNEXT"], "Technology_Description": "Structural biology provides insight into the molecular architecture of cells up to atomic resolution, revealing the biological mechanisms that are fundamental to life. It is thus key to many innovations in chemistry, biotechnology and medicine such as engineered enzymes, new potent drugs, innovative vaccines and novel biomaterials.", "To": ["2019-08-31, ongoing project |"], "Meta": [""], "Topic_s": ["INFRAIA-1-2014-2015 - Integrating and opening existing national and regional research infrastructures of European interest"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Other", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["653706"], "Call_for_Proposal": ["H2020-INFRAIA-2014-2015"]}, -{"Partners": ["UNIVERSITAET ZU KOELN"], "EU_Contribution": ["EUR 2 354 400"], "Project_Title": ["a.r.t.e.s. EUmanities - European Graduate School for the Humanities Cologne"], "Total_Cost": ["EUR 4 708 800"], "Country": ["Germany"], "Project_ACR": ["artes EUmanities"], "Technology_Description": "artes EUmanities offers a doctoral programme (DP) with a mandatory mobility phase, as part of the established artes Graduate School for the Humanities Cologne (AGSHC). Designed around the needs of each individual Early Stage Researcher (ESR) in the Humanities, it will provide places for up to 10 ESRs every year for 3 years.", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2015-DP - Marie Sk\u0142odowska-Curie Co-funding of regional, national and international programmes (COFUND-DP)"], "Funding_scheme": ["MSCA-COFUND-DP - Doctoral programmes"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["713600"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2015"]}, -{"Partners": ["UNIVERSITAET POTSDAM", "THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN", "LANCASTER UNIVERSITY", "UNIVERSITA DEGLI STUDI DI FIRENZE", "UNIVERSIDAD POMPEU FABRA", "STICHTING VU", "FAKULTETA ZA INFORMACIJSKE STUDIJE V NOVEM MESTU", "MEDIZINISCHE UNIVERSITAT GRAZ"], "EU_Contribution": ["EUR 3 878 421,12"], "Project_Title": ["Complex Oscillatory Systems: Modeling and Analysis"], "Total_Cost": ["EUR 3 878 421,12"], "Country": ["Germany", "United Kingdom", "United Kingdom", "Italy", "Spain", "Netherlands", "Slovenia", "Austria"], "Project_ACR": ["COSMOS"], "Technology_Description": "Many natural and artificial systems are often composed of oscillatory elements which, besides evolving according to their own non-trivial internal dynamics, mutually interact. As a result, many temporal and spatial scales are typically present, often accompanied by the spontaneous emergence of collective properties. Altogether, such features make the task of understanding the resulting evolution a challenging interdisciplinary problem. Zero-knowledge methods do generally require too large amount of data to allow drawing meaningful conclusions. In order to overcome this limitation, it is necessary to add skilful hypotheses about the structure of the underlying model and, thereby, on the relevant variables. This task is often tackled in an ad hoc way and the approach is based rather on personal preferences than on objective elements. The goal of this project is to fill the gap, by developing a general and coherent set of tools for the system identification and control, as well as to improve our ability to make predictions. The task will be pursued by combining top-down with bottom-up approaches which will be used to identify the most appropriate variables. Such analysis will be integrated by performing suitable case studies and mutually validating the various techniques to test the correctness of the underlying assumptions (both in the context of theoretical models as well as in experimental time series, such as physiological and neural data). A user-friendly software package will be ultimately developed to make the methods accessible to a broad set of potential users, including those with minimal theoretical competences. Furthermore, we will train a new generation of scientists able to implement a broad range of interdisciplinary approaches to the multivariate time signals that may be generated by the evolution of complex systems.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-EJD - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-EJD)"], "Funding_scheme": ["MSCA-ITN-EJD - European Joint Doctorates"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-01-01"], "Project_ID": ["642563"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["INSTITUT MAX VON LAUE - PAUL LANGEVIN", "EUROPEAN SPALLATION SOURCE ESS AB", "EUROPEAN SPALLATION SOURCE ERIC", "SCIENCE AND TECHNOLOGY FACILITIES COUNCIL", "PAUL SCHERRER INSTITUT", "TECHNISCHE UNIVERSITAET MUENCHEN", "FORSCHUNGSZENTRUM JULICH GMBH", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "TECHNISCHE UNIVERSITEIT DELFT", "HELMHOLTZ-ZENTRUM BERLIN FUR MATERIALIEN UND ENERGIE GMBH", "HELMHOLTZ-ZENTRUM GEESTHACHT ZENTRUM FUR MATERIAL- UND KUSTENFORSCHUNG GMBH", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "KOBENHAVNS UNIVERSITET", "DANMARKS TEKNISKE UNIVERSITET", "NUCLEAR PHYSICS INSTITUTE OF THE ASCR VVI", "CONSORCIO PARA LA CONSTRUCCION, EQUIPAMIENTO Y EXPLOTACION DE LA SEDE ESPANOLA DE LA FUENTE EUROPEA DE NEUTRONES POR ESPALACION", "MAGYAR TUDOMANYOS AKADEMIA ENERGIATUDOMANYI KUTATOKOZPONT", "LABORATORIO DE INSTRUMENTACAO E FISICA EXPERIMENTAL DE PARTICULAS", "UNIVERSITA DEGLI STUDI DI PARMA"], "EU_Contribution": ["EUR 10 863 447"], "Project_Title": ["World class Science and Innovation with Neutrons in Europe 2020 \u2013 SINE2020"], "Total_Cost": ["EUR 12 080 866,25"], "Country": ["France", "Sweden", "Sweden", "United Kingdom", "Switzerland", "Germany", "Germany", "France", "Netherlands", "Germany", "Germany", "Spain", "Denmark", "Denmark", "Czech Republic", "Spain", "Hungary", "Portugal", "Italy"], "Project_ACR": ["SINE2020"], "Technology_Description": "Today\u2019s society is being transformed by new materials and processes. Analytical techniques underpin their development and neutrons, with their unique properties, play a pivotal role in a multi-disciplinary, knowledge-based approach. Industry and the neutron research community must however work together more closely to enhance their innovation potential.", "To": ["2019-09-30, ongoing project |"], "Meta": [""], "Topic_s": ["INFRADEV-4-2014-2015 - Implementation and operation of cross-cutting services and solutions for clusters of ESFRI and other relevant research infrastructure initiatives"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["654000"], "Call_for_Proposal": ["H2020-INFRADEV-1-2014-1"]}, -{"Partners": ["SABANCI UNIVERSITESI", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "AALBORG UNIVERSITET"], "EU_Contribution": ["EUR 418 500"], "Project_Title": ["TACTILENet: Towards Agile, effiCient, auTonomous and massIvely LargE Network of things"], "Total_Cost": ["EUR 517 500"], "Country": ["Turkey", "United Kingdom", "Denmark"], "Project_ACR": ["TACTILENet"], "Technology_Description": "The vision for the 5th generation of mobile networks (5G) includes at its heart the Internet of Things (IoT) paradigm, leading to a new era of connectivity where billions of devices exchange data and instill intelligence in our everyday life. The EU has set out to play a leading role in developing 5G technologies by consolidating and building upon the most important research and innovation results attained in previous research programs. Nevertheless, 5G is still in its early research stages. Various issues must be resolved before it can become a reality: we need to join forces \u2013 across countries, continents, and sectors.", "To": ["2019-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Turkey"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-02-01"], "Project_ID": ["690893"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["MALOPOLSKA VOIVODSHIP", "AKADEMIA GORNICZO-HUTNICZA IM. STANISLAWA STASZICA W KRAKOWIE", "Akademia Sztuk Pieknych im Jana Matejki w Krakowie", "THE HENRYK NIEWODNICZANSKI INSTITUTE OF NUCLEAR PHYSICS, POLISH ACADEMY OF SCIENCES", "POLITECHNIKA KRAKOWSKA", "UNIWERSYTET JAGIELLONSKI", "UNIWERSYTET ROLNICZY IM. HUGONA KOLLATAJA W KRAKOWIE", "INSTYTUT NAUK GEOLOGICZNYCH POLSKIEJ AKADEMII NAUK", "UNIWERSYTET EKONOMICZNY W KRAKOWIE", "KRAKOWSKI SZPITAL SPECJALISTYCZNY IM. JANA PAWLA II", "UNIWERSYTET PEDAGOGICZNY IM KOMISJI EDUKACJI NARODOWEJ W KRAKOWIE", "PANSTWOWA WYZSZA SZKOLA ZAWODOWA W TARNOWIE", "PANSTWOWA WYZSZA SZKOLA ZAWODOWA WNOWYM SACZU"], "EU_Contribution": ["EUR 354 506"], "Project_Title": ["Malopolska Researchers' Night 2014-2015"], "Total_Cost": ["EUR 443 723,50"], "Country": ["Poland", "Poland", "Poland", "Poland", "Poland", "Poland", "Poland", "Poland", "Poland", "Poland", "Poland", "Poland", "Poland"], "Project_ACR": ["Power2Nights"], "Technology_Description": "The project Malopolska Researchers' Night will be implemented in the years 2014 and 2015 respectively for the eighth and ninth time. The event has already permanently inscribed in the calendar of Malopolska scientific events, enjoying growing from year to year popular among participants and becoming one of the biggest Nights in Europe. In 2013, this event was attended by over 55 thousand people, while in the first year of the project (2007) the event was attended only by 3.5 thousand people. The event program specified in the application is even richer than before \u2013 it will take over 1 thousand activities, mainly interactive workshops, presentations, demonstrations and experiments as well as shows with the participation of scientists. It is estimated that 60 thousand people will participate in the events in 2014 and 65 thousand people in 2015. Malopolska Researchers' Night is to first of all show participants how interesting is the work of scientists and how fascinating they are people. Through fun, in accessible and understandable way for everybody, we want to show that all around us is the science, and that scientists in their laboratories are working every day to make our life better, easier and more modern. The main motto of the project for the years 2014 and 2015 will be to present the successes of Malopolska scientists working in international scientific-research teams. The event will be held in six cities of the Region: Krakow, Tarnow, Nowy Sacz and Niepolomice and - for the first time in 2014 - also in Skawina and Andrychow. In addition, it is planned the live broadcast from selected locations via event website. The program will be prepared by almost 900 researchers, more than 1 600 students, about 120 research groups from more than 30 partners. Thanks to the extensive promotional campaign the information about the event will reach to nearly 3.5 million people each year.", "To": ["2015-12-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-NIGHT-2014 - European Researchers' Night (NIGHT)"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Poland"], "Activity": ["Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2014-05-01"], "Project_ID": ["633330"], "Call_for_Proposal": ["H2020-MSCA-NIGHT-2014"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "ACADEMISCH ZIEKENHUIS LEIDEN", "FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION", "THE UNIVERSITY OF LIVERPOOL", "ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOCIENCIAS", "MEDICAL RESEARCH COUNCIL", "JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN", "INSTITUT FUR MOLEKULARE BIOLOGIE GGMBH", "UNIVERSITY OF DUNDEE", "Novo Nordisk A/S"], "EU_Contribution": ["EUR 3 407 194,44"], "Project_Title": ["European Research Training to Decipher The Ub Code : identification of potential biomarkers and drug targets"], "Total_Cost": ["EUR 3 407 194,44"], "Country": ["France", "Germany", "Netherlands", "Switzerland", "United Kingdom", "Spain", "United Kingdom", "Germany", "Germany", "United Kingdom", "Denmark"], "Project_ACR": ["UbiCODE"], "Technology_Description": "Essential role of protein modification by members of the Ubiquitin family: Post-translational modifications (PTM) by members of the Ubiquitin (Ub) family represent an efficient way to regulate protein function at several levels: to change their localisation, activity, their interaction with partner proteins or their stability at the right time and cellular compartment, according to the cell requirements. Defects in this homeostatic equilibrium result in pathologies such as cancer, neurodegeneration, inflammation or multiple infections. For this reason, this research area has become very attractive for fundamental scientists as well as for the pharmaceutical industry aiming to identify potential targets for therapeutic intervention. Ub family members hold a homeostatic equilibrium within the cell and are interconnected in various ways including the regulation of enzymes that control the modified status of target proteins. Interestingly, Ub and Ub-like (UbL) proteins can modify themselves, forming intricate and complex chains. This landscape has recently expanded with the discovery of the formation of heterologous chains among UbL molecules including SUMO or NEDD8 but also other PTMs such as phosphorylation or acetylation. This unsuspected complexity of what is now known as the \u00abUbiquitin Code\u00bb, which is an unknown universal language that needs to be deciphered to understand protein homeostasis and its associated pathologies. To decrypt this complex code requires joint collaborative multidisciplinary efforts at all levels, including the use of distinct molecular systems and model organisms and the latest technological developments to explore chemical, biochemical, molecular, pharmacological and clinical aspects of protein modification by members of the Ub family. UbiCODE represents an unprecedented effort to understand this code in an integrated manner.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-01-01"], "Project_ID": ["765445"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA", "UNIVERSITA DI PISA", "Surflay Nanotec GmbH", "BAYERISCHE JULIUS-MAXIMILIANS UNIVERSITAT WURZBURG", "GESELLSCHAFT FUR ANGEWANDTE MIKRO UND OPTOELEKTRONIK MIT BESCHRANKTERHAFTUNG AMO GMBH", "UNIVERSITA DEGLI STUDI DI GENOVA", "UNIVERSITE DE STRASBOURG", "UNIVERSITY OF CYPRUS"], "EU_Contribution": ["EUR 3 650 589"], "Project_Title": ["SupramolecularlY eNgineered arCHitectures for optoelectRonics and photONICS: a multi-site initial training action"], "Total_Cost": ["EUR 3 650 589"], "Country": ["United Kingdom", "United Kingdom", "Italy", "Italy", "Germany", "Germany", "Germany", "Italy", "France", "Cyprus"], "Project_ACR": ["SYNCHRONICS"], "Technology_Description": "Photonics will play a major, enabling role in the future of ICT and healthcare. However, to fulfill its potential and deliver on its promises, photonics will heavily rely on novel and more performing materials, that can be manufactured cheaply for the specific requirements of photonic applications. To lead this \u201cphotonics revolution\u201d and rip the societal benefits of being at the leading-edge of novel technological and scientific developments, the EC needs a highly-skilled scientific and technical workforce that can effectively implement the transition to a truly \u201cknowledge-based society\u201d.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Chiara Andreoli", "Tel.: +3901071781854", "Fax: +39 010 7170817", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Other", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-01-01"], "Project_ID": ["643238"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6", "NACIONALNI INSTITUT ZA BIOLOGIJO", "STICHTING NIOZ, KONINKLIJK NEDERLANDS INSTITUUT VOOR ONDERZOEK DER ZEE", "HELSINGIN YLIOPISTO", "INSTYTUT OCEANOLOGII POLSKIEJ AKADEMII NAUK", "UNIWERSYTET GDANSKI", "NATIONAL UNIVERSITY OF IRELAND GALWAY", "GOETEBORGS UNIVERSITET", "UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA", "HELLENIC CENTRE FOR MARINE RESEARCH", "THE HEBREW UNIVERSITY OF JERUSALEM", "STAZIONE ZOOLOGICA ANTON DOHRN", "UNIVERSITETET I BERGEN", "CENTRO DE CIENCIAS DO MAR DO ALGARVE", "ALFRED-WEGENER-INSTITUT HELMHOLTZ-ZENTRUM FUR POLAR- UND MEERESFORSCHUNG", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "VLAAMS INSTITUUT VOOR DE ZEE VZW", "THE SCOTTISH ASSOCIATION FOR MARINESCIENCE LBG", "THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS", "MARINE BIOLOGICAL ASSOCIATION OF THE UNITED KINGDOM", "NATURAL ENVIRONMENT RESEARCH COUNCIL", "MARINE SCOTLAND", "AquaTT UETP Ltd"], "EU_Contribution": ["EUR 9 999 911,47"], "Project_Title": ["Association of European Marine Biological Laboratories Expanded"], "Total_Cost": ["EUR 9 999 911,48"], "Country": ["France", "Slovenia", "Netherlands", "Finland", "Poland", "Poland", "Ireland", "Sweden", "Spain", "Greece", "Israel", "Italy", "Norway", "Portugal", "Germany", "Germany", "Belgium", "United Kingdom", "United Kingdom", "United Kingdom", "United Kingdom", "United Kingdom", "Ireland"], "Project_ACR": ["ASSEMBLE Plus"], "Technology_Description": "Marine biological stations have offered services and biological resources to science for more than a century. ASSEMBLE Plus will provide scientists from academia, industry and policy with a quality-assured programme of Transnational Access (TA) and Virtual Access (VA) to marine biological stations offering a wide variety of marine ecosystems, unique marine biological resources, state-of-the-art experimental and analytical facilities with integrated workflows, historical observation data, and advanced training opportunities. The goal is to stimulate European excellence in fundamental and applied research in marine biology and ecology, thereby improving our knowledge- and technology-base for the blue economy, policy and education. ASSEMBLE Plus brings together 33 marine stations and institutes with modern research infrastructure and track-records of unique service provision from 14 European and associated countries under the leadership of the European Marine Biological Resource Centre (EMBRC), an ESFRI consortium developed from the previous ASSEMBLE (FP7) partnership. Joint Research Activities involving all partners aim to develop innovative new technologies and/or methodologies to be offered to users through the TA and VA programmes. A coherent series of Networking Activities (NAs) will strengthen the culture of cooperation within and beyond the consortium, providing benchmarks for refined practices of service provision, disseminating interoperable protocols, engaging with novel user communities, and sharing insights into business strategies. The sum of the actions envisaged in ASSEMBLE Plus will ultimately increase the number of users of marine biological stations and shape novel strategic development perspectives, to be based on effective integration and efficient complementarities, resulting in a key contribution to their long-term sustainability.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["INFRAIA-01-2016-2017 - Integrating Activities for Advanced Communities"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Other"], "From": ["2017-10-01"], "Project_ID": ["730984"], "Call_for_Proposal": ["H2020-INFRAIA-2016-1"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Comprehensive code for stellar dating, and analysis of exoplanetary systems observed by direct imaging"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["THOT"], "Technology_Description": "THOT is an ambitious project for delivering estimated ages for large numbers of stars in the Galaxy. The main aims of THOT are: 1) To gather all the techniques for stellar dating, 2) to update those having the most potential for application to data from new and upcoming missions, 3) to develop a code to automate stellar dating and, 4) to apply this code to study exoplanetary systems observed by direct imaging. This ambitious programme will be delivered at the University of Birmingham (UoB) by Dr. Moya, supervised by Prof. William Chaplin in close collaboration with Drs. A. Miglio and G. Davies. A two-year plan including working packages, deliverables, milestones, and training objectives is presented, showing the feasibility and innovation of the project. THOT has three secondments planned at different academic institutes: 1) CAB \u2013 INTA/CSIC, Spain, Dr. David Barrado, 2) IA, Portugal, Dr. Elisa Delgado, and 3) UNED, Spain, Dr. Luis Manuel Sarro. These secondments complement the needed skills for the project and open key collaboration lines for THOT and for the long-term project for which THOT is the first step: an EU collaboration network for stellar dating and the development of a \u201cmap of ages\u201d to understand how the region of the Galaxy around our Sun evolves. Because of his career, Dr. Moya will be able to make the most of this fellowship opportunity. The Solar and Stellar group, led by Prof. Chaplin at UoB, is the best option for him to deliver success. The proven leadership and independent thinking of Dr. Moya, together with the new opportunities and skills that the UoB research group offers, will provide a major boost to Dr. Moya\u2019s scientific career. A complete plan for dissemination, exploitation and communication of the results is also presented. The UoB is committed to the successful outcome of THOT. UoB and the institutes that will host the secondments all have proven track records of successfully hosting Marie Curie fellows as outlined in Part B section 5.", "To": ["2019-10-15, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-16"], "Project_ID": ["749962"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["VEREIN EURESEARCH", "Ministerio de Ciencia, Tecnolog\u00eda e Innovaci\u00f3n Productiva", "BULGARIAN ACADEMY OF SCIENCES", "AGENCIJA ZA MOBILNOST I PROGRAME EUROPSKE UNIJE", "IDRYMA PROOTHISIS EREVNAS", "ACADEMY OF SCIENTIFIC RESEARCH AND TECHNOLOGY ASRT", "SIHTASUTUS EESTI TEADUSAGENTUUR", "ETHNIKO IDRYMA EREVNON", "RANNSOKNAMIDSTOD ISLANDS", "AGENZIA PER LA PROMOZIONE DELLA RICERCA EUROPEA", "IRISH UNIVERSITIES ASSOCIATION", "MATIMOP - THE ISRAELI CENTER FOR R&D", "INSTYTUT PODSTAWOWYCH PROBLEMOW TECHNIKI POLSKIEJ AKADEMII NAUK", "UNIVERSITATEA DE STIINTE AGRICOLE SI MEDICINA VETERINARA A BANATULUI REGELE MIHAI I AL ROMANIEI DIN TIMISOARA", "TURKIYE BILIMSEL VE TEKNOLOJIK ARASTIRMA KURUMU"], "EU_Contribution": ["EUR 1 498 353"], "Project_Title": ["Net4Mobility: Network of the Marie Sk\u0142odowska-Curie Actions National Contact Points"], "Total_Cost": ["EUR 1 777 949,25"], "Country": ["Switzerland", "Argentina", "Bulgaria", "Croatia", "Cyprus", "Egypt", "Estonia", "Greece", "Iceland", "Italy", "Ireland", "Israel", "Poland", "Romania", "Turkey"], "Project_ACR": ["Net4Mobility"], "Technology_Description": "The objective of the Net4Mobility project is to facilitate the transnational cooperation between the National Contact Points (NCPs) of the Marie Sklodowska-Curie Actions (MSCA). The project aims to achieve the following two goals: 1) mutual support and thus raising the general standard of applicants (taking into account the diversity of the different actors) 2) to better inform the research and innovation stakeholders on funding possibilities in the MSCA and help them to improve their performance. Thus, ultimately our goal is to support research and innovation. As a synergy effect, the work processes of REA, EC and NCPs will be optimized and more effective. ", "To": ["2018-01-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-NCP-2014 - Trans-national cooperation among Marie Sk\u0142odowska-Curie National Contact Points (NCP)"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Switzerland"], "Activity": ["Other", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Other", "Higher or Secondary Education Establishments", "Other", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2015-02-01"], "Project_ID": ["640603"], "Call_for_Proposal": ["H2020-MSCA-NCP-2014"]}, -{"Partners": ["THE CYPRUS INSTITUTE", "UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA", "HUMBOLDT-UNIVERSITAET ZU BERLIN", "BERGISCHE UNIVERSITAET WUPPERTAL", "UNIVERSITY OF CYPRUS", "UNIVERSITA DEGLI STUDI DI FERRARA", "RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN", "THE HEBREW UNIVERSITY OF JERUSALEM"], "EU_Contribution": ["EUR 3 755 601"], "Project_Title": ["Simulation in multiscale physical and biological systems"], "Total_Cost": ["EUR 3 755 601"], "Country": ["Cyprus", "Italy", "Germany", "Germany", "Cyprus", "Italy", "Germany", "Israel"], "Project_ACR": ["STIMULATE"], "Technology_Description": "Simulation alongside theory and experiment is nowadays considered an integral part of scientific discovery. As computation speeds up and new technologies and instruments improve, data generation in all fields of science is rapidly increasing. As a consequence, researchers face new challenges: Data collection exceeds by far the capacity to validate, analyze, visualize, store, and curate the information contained. Additionally, traditional, single-scale, macroscopic physical models are becoming inadequate for the accuracy requirements of modern physical, biological and engineering applications that involve multiscale phenomena occurring over vastly different scales. Tackling these challenges will transform our approach to research potentially leading to unprecedented data-driven scientific discoveries. The overall goal of STIMULATE is to deliver an innovative interdisciplinary educational and research program in simulation and data science, which educates students to best address the challenges posed by exascale computing and intensive data applications, producing computational science professionals tactically positioned to become leaders in both academia and industry. The project proposes a rigorous network-wide training program and research projects that combine mathematical modeling and algorithms for exascale simulations and data-intensive science with applications in the fields of Computational Fluid Dynamics, Computational Biology and Particle and Nuclear Physics with focus in lattice Quantum Chromodynamics. Students will be seconded to industrial partners that will complement expertise in computer technologies, mathematical modeling and data analytics with hands-on training. Experts from eight degree-awarding institutions, three research centers and three companies are engaged in the project. Each of the fifteen fellows of the program will obtain a single joint Ph.D. degree from three academic institutions.", "To": ["2022-05-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EJD - European Joint Doctorates"], "Coordinated_in": ["Cyprus"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-06-01"], "Project_ID": ["765048"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["ROYAL COLLEGE OF SURGEONS IN IRELAND", "LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN", "UNIVERSIDAD COMPLUTENSE DE MADRID", "INSTITUTE OF EXPERIMENTAL MEDICINE - HUNGARIAN ACADEMY OF SCIENCES", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "CENTRO DE INVESTIGACION BIOMEDICA EN RED ENFERMEDADES NEURODEGENERATIVAS", "SARISSA BIOMEDICAL LIMITED", "BIOTALENTUM TUDASFEJLESZTO KFT", "FUNDACION TEOFILO HERNANDO"], "EU_Contribution": ["EUR 3 487 463,28"], "Project_Title": ["Interdisciplinary training network on the purinergic P2X7 receptor to control neuroinflammation and hyperexcitability in brain diseases."], "Total_Cost": ["EUR 3 487 463,28"], "Country": ["Ireland", "Germany", "Spain", "Hungary", "Germany", "Spain", "United Kingdom", "Hungary", "Spain"], "Project_ACR": ["PurinesDX"], "Technology_Description": "Brain disorders affect ~179 million people and their families in Europe alone, with an annual cost to the taxpayer estimated at \u20ac800 billion- a greater economic burden than cardiovascular disease and cancer combined. Despite diverse etiology, overlap in clinical symptoms and comorbidities between brain disorders suggests shared patho-mechanisms. In particular, hyperexcitible states driven by glial activation and neuroinflammation appear near ubiquitous. Targeting these mechanisms offers the potential to ameliorate symptoms and reverse disease progression across a broad span of brain disorders. Functioning as a gatekeeper to neuroinflammation and mechanistic link between neuronal hyperexcitability and glial activation, the ATP-gated, ionotropic purinergic P2X7 receptor (P2X7R) offers the most promising target for pharmacological intervention in the neuroinflammation-hyperexcitability pathway, to date. With breakthroughs in understanding P2X7R function, highly promising effects demonstrated for antagonists in models of brain disease and vast investment in P2X7R-related drug development programmes, now is the perfect time to pool resources. PurinesDX brings together global leaders in translational research in purinergic signalling, Europe\u2019s leading clinical specialists in a broad range of brain diseases, and industrial partners specializing in drug and biomarker development. Sharing unique genetic tools, newly developed diagnostic devices and novel, selective and brain-stable P2X7R antagonists, the synergism facilitated within PurinesDX will extend to the training of an urgently needed new generation of highly skilled, innovative, creative and entrepreneurial scientists. Alongside the provision of this interdisciplinary, international and intersectoral environment, an original and high level training in state-of-the-art neuroscience will be provided, nurturing a cohort of highly competitive researchers with potential to drive a new era of neuroscience research.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["766124"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET", "UNIVERSITE DU LUXEMBOURG", "UNIVERSIDAD REY JUAN CARLOS", "CARDIFF UNIVERSITY", "REGION HOVEDSTADEN", "3SHAPE TRIOS AS", "GMV SOLUCIONES GLOBALES INTERNET SAU", "SYNOPSYS (NORTHERN EUROPE) LIMITED", "AALBORG UNIVERSITET"], "EU_Contribution": ["EUR 4 013 444,88"], "Project_Title": ["Rapid Biomechanics Simulation for Personalized Clinical Design"], "Total_Cost": ["EUR 4 013 444,88"], "Country": ["Denmark", "Luxembourg", "Spain", "United Kingdom", "Denmark", "Denmark", "Spain", "United Kingdom", "Denmark"], "Project_ACR": ["RAINBOW"], "Technology_Description": "Clinical experts make design decisions on treatments, interventions, or on devices. ICT empowers them with patient-specific simulation models that enable better-informed design decisions. But patient-specific computational medicine is currently cumbersome, slow, and unintuitive; it relies on complex processing by technical experts, and it is hence far from reaching its full potential on clinical design, and scarcely used.", "To": ["2022-03-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2018-04-01"], "Project_ID": ["764644"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["UNIVERSITETET I OSLO", "STICHTING NATURALIS BIODIVERSITY CENTER", "GOETEBORGS UNIVERSITET", "KOBENHAVNS UNIVERSITET", "ROYAL BOTANIC GARDENS KEW", "ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS", "AGENTSCHAP PLANTENTUIN MEISE", "BASECLEAR BV", "ROYAL BOTANIC GARDEN EDINBURGH"], "EU_Contribution": ["EUR 4 062 035,52"], "Project_Title": ["Molecular Identification of Plants"], "Total_Cost": ["EUR 4 062 035,52"], "Country": ["Norway", "Netherlands", "Sweden", "Denmark", "United Kingdom", "Greece", "Belgium", "Netherlands", "United Kingdom"], "Project_ACR": ["Plant.ID"], "Technology_Description": "Many of the nearly 400,000 species of plants provide food, feed, medicines, and construction materials. Besides these positive impacts, plants also affect us negatively through pollen allergies, poisonous species, as invasive species, and as adulterants in herbal medicines. Nevertheless, plants are the most promising biological resource for our future. Current extinction risks of global flora and vast decline in taxonomic expertise demand accurate and rapid identification approaches to understand and valorise botanical biodiversity. Advances in genomic data and DNA sequencing are revolutionizing plant systematics, and modern molecular identification methods make it possible to accurately determine plants in ways that were technically impossible only a decade ago. Recently, it has become possible to detect substitution in herbal pharmaceuticals, monitor invasive alien species, trace fragments such as pollen and spores, uncover illegal trade in endangered species, make rapid and accurate molecular biodiversity assessments, and study historical plant diversity through DNA in museum specimens. However, to efficiently harvest the potential of the opportunities provided by the new genomic techniques, society today is in urgent need of trained biosystematists experienced in both taxonomy and in handling enormous amounts of genomic data. Plant.ID will innovatively address these challenges by bringing together academic and non-academic partners including regulatory agencies, industry, SMEs and NGO stakeholders, with the aim of developing molecular identification of plants through tailored approaches to species delimitation, metabarcoding, gene capture, and genomic barcoding, in order to empower stakeholders with simplified molecular identification of plants. By bridging classical taxonomic expertise with cutting-edge genomic approaches, Plant.ID will train a new generation of ESRs who will have immediate relevance to harnessing the central role of plants in the modern world.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["765000"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["ACADEMISCH ZIEKENHUIS GRONINGEN", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "THE UNIVERSITY OF NOTTINGHAM", "UNIVERSITATSKLINIKUM ERLANGEN", "CHARITE - UNIVERSITAETSMEDIZIN BERLIN", "OTICON A/S", "WIDEX AS", "COCHLEAR RESEARCH AND DEVELOPMENT LIMITED"], "EU_Contribution": ["EUR 3 928 915,08"], "Project_Title": ["Research School for TINnitus Assessment, Causes and Treatments"], "Total_Cost": ["EUR 3 928 915,08"], "Country": ["Netherlands", "France", "United Kingdom", "Germany", "Germany", "Denmark", "Denmark", "United Kingdom"], "Project_ACR": ["TIN-ACT"], "Technology_Description": "Tinnitus (\u201cringing in the ears\u201d) is a very common and potentially devastating condition. People with tinnitus, continuously hear a penetrating phantom sound in absence of actual sound. An estimated 50.8 million EU citizens hear tinnitus, of which 5.1 million are severely bothered by it. Tinnitus can totally disrupt normal societal participation. Hence, tinnitus leads to enormous societal costs (\u20ac140 billion per year in Europa), mainly due to loss of productivity. Since tinnitus primary occurs at advanced age (>50 years), it is a severe challenge to the European ambition to continued inclusion of the aging population in the work force. To date, the research into tinnitus has progressed almost nowhere in the development of effective and reliable treatments for tinnitus. The applicants of the current proposal are convinced that in order to cure tinnitus, we need researchers that can bridge the gap between basic fundamental research, applied clinical research and product development. The major aim of the proposal is to train 15 future scientists who understand how basic neural mechanisms of tinnitus can be studied in animal models and human tinnitus patients, and how complementary research techniques can be used towards curing tinnitus. The central hypothesis of TIN-ACT is that reduced peripheral auditory input (via hearing loss) causes pathological changes centrally in the brain that manifest as the perception of tinnitus. In a balanced consortium, the research is organized in three scientific work packages that study how these pathological changes can be assessed, what causes them, and how they can be treated. A comprehensive training program provides specialized training by research, complementary skills and soft skills (including entrepreneurship). We will train 15 early stage researchers (ESRs) towards an excellent understanding of tinnitus assessment, causes and treatments, and with job perspectives both in the academic and non-academic sectors.", "To": ["2021-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-11-01"], "Project_ID": ["764604"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["FUNDACIO PRIVADA INSTITUT CATALA D'INVESTIGACIO QUIMICA", "UNIVERSITE DE NEUCHATEL", "FREIE UNIVERSITAET BERLIN", "THE UNIVERSITY OF WARWICK", "CONSIGLIO NAZIONALE DELLE RICERCHE", "INSTITUTE OF ORGANIC CHEMISTRY - POLISH ACADEMY OF SCIENCES", "UNIVERSITE DE STRASBOURG", "MIND THE BYTE SL", "COVESTRO DEUTSCHLAND AG"], "EU_Contribution": ["EUR 2 525 640,84"], "Project_Title": ["Network of Functional Molecular Containers with Controlled Switchable Abilities"], "Total_Cost": ["EUR 2 525 640,84"], "Country": ["Spain", "Switzerland", "Germany", "United Kingdom", "Italy", "Poland", "France", "Spain", "Germany"], "Project_ACR": ["NOAH"], "Technology_Description": "NOAH deals with the education of early-stage researchers (ESRs) in a multidisciplinary chemical research program within the area of functional molecular containers, encapsulation processes and their applications with the possibility to end up with a PhD degree. The proposed training network aims to bring in a great variety of scientific attributes to 10 selected ESRs, ranging from the experimental organic and inorganic synthesis to computational chemistry. Photo- and electro-chemistry, MS/gas-phase chemistry, X-ray diffraction and optical spectroscopy techniques will be also included in the scientific formation and development of the recruited ESRs. The trainees will also receive education in complementary and transferable skills through attendance to local and network-wide dedicated training seminars (e.g. dissemination, communication, organization, governance, ethics\u2026). The training program includes the exposure of the ESRs to chemical research carried out in the non-academic sector or in a technological centre by means of full recruitment or short stage secondments in one of the three chemical European companies or the technological centre operating at very different levels: one large company, Covestro, two SMEs, Mind the Byte and Biolitec and one technological centre Leitat. ESRs will also gain insight in the transfer process of knowledge from academia to industry and other complementary soft-skills. The proposed ETN constitutes an ideal framework to acquaint ESRs, in a modest amount of time (3 years), with a great variety of scientific skills, experimental techniques, soft-skills and technologies. Ten ESRs will be incorporated in a multidisciplinary team formed by 7 research groups of multiple nationalities that are focused on a common goal and with high involvement of 3 non-academic partners and one technological centre. All PIs are internationally recognized scientists and the scholar scientists have wide experience as tutors and mentors of ESRs.", "To": ["2022-03-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-04-01"], "Project_ID": ["765297"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["UNIVERZA V LJUBLJANI", "UNIVERSITA DEGLI STUDI DI MILANO", "UNIVERSITEIT UTRECHT", "UNIVERSITAET BASEL", "LUNDS UNIVERSITET", "UNIVERSITE GRENOBLE ALPES"], "EU_Contribution": ["EUR 3 080 389,68"], "Project_Title": ["Multidisciplinary European Joint Doctorate in the Design and Development of Glyco Drugs"], "Total_Cost": ["EUR 3 080 389,68"], "Country": ["Slovenia", "Italy", "Netherlands", "Switzerland", "Sweden", "France"], "Project_ACR": ["PhD4GlycoDrug"], "Technology_Description": "The PhD4GlycoDrug consortium has a main goal to offer a European Joint Doctorate educational training network in Glyco-Drug Discovery and Development. The network combines 6 academic partners with long tradition in PhD training and accredited doctoral studies in Organic Chemistry, Medicinal Chemistry, Structural Biology and Pharmacology/Pharmacy. Non-academic partners, 5 SMEs and a research institute also constitute the consortium to offer intersectoral exposure and quality training in transferable skills to entrepreneurial ESRs.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EJD - European Joint Doctorates"], "Coordinated_in": ["Slovenia"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["765581"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["QUEEN MARY UNIVERSITY OF LONDON", "UNIVERSIDAD POMPEU FABRA", "INSTITUT MINES-TELECOM", "UNIVERSITAT LINZ", "SONY EUROPE LIMITED", "DOREMIR MUSIC RESEARCH AB", "ROLI Ltd"], "EU_Contribution": ["EUR 3 937 088,16"], "Project_Title": ["New Frontiers in Music Information Processing"], "Total_Cost": ["EUR 3 937 088,16"], "Country": ["United Kingdom", "Spain", "France", "Austria", "United Kingdom", "Sweden", "United Kingdom"], "Project_ACR": ["MIP-Frontiers"], "Technology_Description": "Music Information Processing (also known as Music Information Research; MIR) involves the use of information processing methodologies to understand and model music, and to develop products and services for creation, distribution and interaction with music and music-related information. MIR has reached a state of maturity where there are standard methods for most music information processing tasks, but as these have been developed and tested on small datasets, the methods tend to be neither robust to different musical styles or use contexts, nor scalable to industrial scale datasets. To address this need, and to train a new generation of researchers who are aware of, and can tackle, these challenges, we bring together leading MIR groups and a wide range of industrial and cultural stakeholders to create a multidisciplinary, transnational and cross-sectoral European Training Network for MIR researchers, in order to contribute to Europe's leading role in this field of scientific innovation, and accelerate the impact of innovation on European products and industry.", "To": ["2022-03-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-04-01"], "Project_ID": ["765068"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["UNIVERSITEIT TWENTE", "GENERAL ELECTRIC DEUTSCHLAND HOLDING GMBH", "TECHNISCHE UNIVERSITAET MUENCHEN", "KARLSRUHER INSTITUT FUER TECHNOLOGIE", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "CENTRE EUROPEEN DE RECHERCHE ET DE FORMATION AVANCEE EN CALCUL SCIENTIFIQUE", "ASSOCIATION POUR LA RECHERCHE ET LE DEVELOPPEMENT DES METHODES ET PROCESSUS INDUSTRIELS", "SAFRAN SA", "SAFRAN HELICOPTER ENGINES", "ANSYS FRANCE SAS"], "EU_Contribution": ["EUR 3 873 159"], "Project_Title": ["Machine learning for Advanced Gas turbine Injection SysTems to Enhance combustoR performance."], "Total_Cost": ["EUR 3 873 159"], "Country": ["Netherlands", "Germany", "Germany", "Germany", "United Kingdom", "France", "France", "France", "France", "France"], "Project_ACR": ["MAGISTER"], "Technology_Description": "Air transportation is expected to grow persistently over the next decades. Clean combustion technology for aircraft engines is a key enabler to reduce the impact of this growth on ecosystems and humans\u2019 health. The vision for European aviation is shaped by the Advisory Council for Aviation Research and Innovation in Europe in the Flight Path 2050 goals, which define stringent regulations on pollutant emissions. To meet these goals, the major engine manufacturers develop lean premixed combustors operated at very high pressure. This development introduces a large risk for reduced reliability and lifetime of engines: pressure oscillations in the combustor called thermoacoustics. Much research has been dedicated to study this phenomenon over the last decades with mixed success. Industrial experience shows that the pressure oscillations often surface as late as the full engine has been built and tested. Traditional engineering methods fall short of predictability during the design of the engines due to a high sensitivity of thermoacoustics with respect to barely known input parameters. Aviation industry encounters currently the fourth industrial revolution: cyber-physical systems analyze and monitor technical systems and take automated decisions. This industrial revolution is known as \u201cIndustry 4.0\u201d in Germany and \u201cIndustrial Internet\u201d in the USA. An essential enabler of the fourth industrial revolution is Machine Learning. The ITN MAGISTER will utilize Machine Learning to predict and understand thermoacoustics in aircraft engine combustors, and lead combustion research a revolutionary new approach in this area. The participation of the major aircraft engine OEMs GE, Rolls Royce, Safran ensures industrial relevance and outreach of the results. The project will shape early career talents in a network of world leading scientists and industrial partners to work on one of the most severe design issues in aviation technology in the spirit of the fourth industrial revolution.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-09-01"], "Project_ID": ["766264"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["EBERHARD KARLS UNIVERSITAET TUEBINGEN", "MEDIZINISCHE UNIVERSITAET WIEN", "ACADEMISCH ZIEKENHUIS GRONINGEN", "KATHOLIEKE UNIVERSITEIT LEUVEN", "KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN", "REGION HOVEDSTADEN", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "KING'S COLLEGE LONDON", "ABX CRO ADVANCED PHARMACEUTICAL SERVICES FORSCHUNGSGESELLSCHAFT MBH", "PHILIPS ELECTRONICS NEDERLAND B.V.", "SIEMENS HEALTHCARE GMBH"], "EU_Contribution": ["EUR 3 858 940,08"], "Project_Title": ["Innovative Training Network towards raising and supporting the next generation of creative and entrepreneurial cross-speciality imaging experts"], "Total_Cost": ["EUR 3 858 940,08"], "Country": ["Germany", "Austria", "Netherlands", "Belgium", "Germany", "Denmark", "France", "United Kingdom", "Germany", "Netherlands", "Germany"], "Project_ACR": ["HYBRID"], "Technology_Description": "Modern medicine seeks to personalize diagnosis and treatment to the needs of individual patients. Personalized medicine approaches use non-invasive imaging to detect and characterize disease. While anatomical and molecular imaging systems have become a commodity, these systems have also grown complex. Complexity is further increased by the introduction of combined (hybrid) imaging systems, such as PET/CT, SPECT/CT or PET/MR. Within the context of hybrid imaging, these systems provide multi-parametric image information that has proven promising in rendering diagnoses and subsequent therapeutic management of patients more effective. The growing complexity of diagnostic and therapeutic regimens in light of the drive to integrate multiple layers of biomarker information no longer supports the operation of hybrid imaging modalities by singular specialists, but instead requires a new generation of open-minded, technology-fluent and applications-oriented experts. ", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-10-01"], "Project_ID": ["764458"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["UNIVERSITEIT ANTWERPEN", "UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6", "UNIVERSIDAD DE VALLADOLID", "LATVIJAS ORGANISKAS SINTEZES INSTITUTS", "ITA-SUOMEN YLIOPISTO", "KLINIKUM DER UNIVERSITAET ZU KOELN", "INSTITUTO DE BIOLOGIA EXPERIMENTAL E TECNOLOGICA"], "EU_Contribution": ["EUR 3 002 689,44"], "Project_Title": ["Integrated Training in Dry Eye Disease Drug Development (IT-DED3)"], "Total_Cost": ["EUR 3 002 689,44"], "Country": ["Belgium", "France", "Spain", "Latvia", "Finland", "Germany", "Portugal"], "Project_ACR": ["IT-DED3"], "Technology_Description": "The European network for Integrated Training in Dry Eye Disease Drug Development (IT-DED3) aims to deliver multidisciplinary and entrepreneurial researchers trained to develop new therapies for patients suffering from dry eye diseases (DED). DED is a chronic, multifactorial disease of the ocular surface and is a major and increasing healthcare problem due to its high prevalence and economic burden because of the ageing population and frequent computer/tablet/smartphone usage.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["765608"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["DUBLIN CITY UNIVERSITY"], "EU_Contribution": ["EUR 175 866"], "Project_Title": ["Knowledge Discovery in Data as Collaboration of Human and Software Actors"], "Total_Cost": ["EUR 175 866"], "Country": ["Ireland"], "Project_ACR": ["KDD-CHASER"], "Technology_Description": "The KDD-CHASER project aims to develop a process model and software platform for collaborative knowledge discovery in data (KDD). Traditionally, KDD has been an expert-driven process, but more recently, special types of KDD processes have begun to emerge that involve non-expert individuals in various roles. With sufficiently intelligent software tools, it is even possible for such individuals to take charge of the process and use KDD to extract useful knowledge from their own personal data, but this possibility is not adequately covered by the established process model of KDD. The project addresses this problem by exploring the requirements of incorporating autonomous software and non-expert humans as actors in the KDD process and distilling these into a new process model, consisting of a data model and a workflow model, that satisfies the requirements.", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["746837"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG", "CONSIGLIO NAZIONALE DELLE RICERCHE", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "STICHTING CENTRUM VOOR WISKUNDE EN INFORMATICA", "COMPAGNIE IBM FRANCE SA", "MANAGEMENT, ARTIFICIAL INTELLIGENCE AND OPERATIONS RESEARCH SOCIETA' A RESPONSABILITA' LIMITATA", "TECHNISCHE UNIVERSITAT DORTMUND", "RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG", "ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA", "UNIVERSITAET KLAGENFURT", "STICHTING KATHOLIEKE UNIVERSITEIT BRABANT", "UNIVERSITAET ZU KOELN"], "EU_Contribution": ["EUR 3 063 483,72"], "Project_Title": ["Mixed-Integer Non-Linear Optimisation Applications"], "Total_Cost": ["EUR 3 063 483,72"], "Country": ["Germany", "Italy", "France", "Netherlands", "France", "Italy", "Germany", "Germany", "Italy", "Austria", "Netherlands", "Germany"], "Project_ACR": ["MINOA"], "Technology_Description": "Building upon the achievements of the Marie-Curie ITN Mixed-Integer Non-Linear Optimization (MINO) (2012 - 2016), the goal of the Mixed-Integer Non-Linear Optimisation Applications (MINOA) proposal is to train the next generation of highly qualified researchers and managers in applied mathematics, operations research and computer science that are able to face the modern imperative challenges of European and international relevance in areas such as energy, logistics, engineering, natural sciences, and data analytics. Twelve Early-Stage Researchers (ESRs) will be trained through an innovative training programme based on individual research projects motivated by these applications that due to their high complexity will stimulate new developments in the field. The mathematical challenges can neither be met by using a single optimisation method alone, nor isolated by single academic partners. Instead, MINOA aims at building bridges between different mathematical methodologies and at creating novel and effective algorithmic enhancements. As special challenges, the ESRs will work on dynamic aspects and optimisation in real time, optimisation under uncertainty, multilevel optimization and non-commutativity in quantum computing. The ESRs will devise new effective algorithms and computer implementations. They will validate their methods for the applications with respect to metrics that they will define. All ESRs will derive recommendations, both for optimised MINO applications and for the effectiveness of the novel methodologies. These ESRs belong to a new generation of highly-skilled researchers that will strengthen Europe'e human capital base in R&I in the fast growing field of mathematical optimisation. The ESR projects will be pursued in joint supervision between experienced practitioners from leading European industries and leading optimisation experts, covering a wide range of scientific fields (from mathematics to quantum computing and real-world applications).", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["764759"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["ETHNIKO IDRYMA EREVNON", "HITS GGMBH", "UNIVERSITA' DEGLI STUDI DI SIENA", "UNIVERSITE DE CAEN NORMANDIE", "ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON", "TECHNISCHE UNIVERSITAET DRESDEN", "AvantiCell Science Ltd", "FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS", "THE UNIVERSITY OF SHEFFIELD", "STICHTING VU"], "EU_Contribution": ["EUR 3 555 758,88"], "Project_Title": ["A European training network for the discovery of neurotrophins small molecule mimetics as candidate therapeutic agents for neurodegeneration and neuroinflammation"], "Total_Cost": ["EUR 3 555 758,88"], "Country": ["Greece", "Germany", "Italy", "France", "Greece", "Germany", "United Kingdom", "Greece", "United Kingdom", "Netherlands"], "Project_ACR": ["EuroNeurotrophin"], "Technology_Description": "Neurodegenerative diseases (ND) like AD, PD, MS and ALS/MND are on the rise in developed societies worldwide. Currently, there exists no cure for any ND, and most of the available drugs fail to tackle ND pathogenesis. Preclinical studies point to the therapeutic potential of neurotrophins, which have been shown to control a number of aspects of survival, development and function of neurons. However, the poor pharmacokinetic properties of neurotrophins render their use as drugs prohibitive.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Greece"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["765704"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["UNIVERSITEIT ANTWERPEN", "ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM", "FORSCHUNGSZENTRUM JULICH GMBH", "THE UNIVERSITY OF SHEFFIELD", "UNIVERSITAIR ZIEKENHUIS ANTWERPEN", "SYNTHETIC MR AB (PUBL)", "ICOMETRIX NV", "MRR SYSTEMS LIMITED", "QUANTIB BV", "SIEMENS HEALTHCARE"], "EU_Contribution": ["EUR 3 874 166,64"], "Project_Title": ["Breakthroughs in Quantitative Magnetic resonance ImagiNg for improved DEtection of brainDiseases"], "Total_Cost": ["EUR 3 874 166,64"], "Country": ["Belgium", "Netherlands", "Germany", "United Kingdom", "Belgium", "Sweden", "Belgium", "United Kingdom", "Netherlands", "Belgium"], "Project_ACR": ["B-Q MINDED"], "Technology_Description": "Magnetic resonance imaging (MRI) is one of the most useful and rapidly growing neuroimaging tools. Unfortunately, signal intensities in conventional MRI images are expressed in relative units that depend on scanner hardware and acquisition protocols. While this does not hinder visual inspection of anatomy, it hampers quantitative comparison of tissue properties within a scan, between successive scans, and between subjects. In contrast, advanced quantitative MRI (Q-MRI) methods like MR relaxometry or diffusion MRI do enable absolute quantification of biophysical tissue characteristics. Evidence is growing that Q-MRI techniques detect subtle microscopic damage, enabling more accurate and early diagnosis of neurodegenerative diseases. However, due to the long scan time required for Q-MRI, causing discomfort for patients and limiting the throughput, Q-MRI methods have not entered clinical practice yet. ", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-01-01"], "Project_ID": ["764513"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["UNIVERSITY OF BATH", "FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA", "UNIVERSITAT JAUME I DE CASTELLON", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "\"NATIONAL CENTER FOR SCIENTIFIC RESEARCH \"\"DEMOKRITOS\"\"\"", "UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA", "BAR ILAN UNIVERSITY", "SWANSEA UNIVERSITY", "UNIVERSITAT KONSTANZ", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "OXFORD PHOTOVOLTAICS LIMITED", "3GSOLAR PHOTOVOLTAICS LTD", "GREATCELL SOLAR UK LIMITED", "UAB MODERNIOS E-TECHNOLOGIJOS", "SAULE SP ZOO"], "EU_Contribution": ["EUR 3 852 446,40"], "Project_Title": ["MAking pErovskiteS TRuly explOitable"], "Total_Cost": ["EUR 3 852 446,40"], "Country": ["United Kingdom", "Italy", "Spain", "United Kingdom", "Greece", "Italy", "Israel", "United Kingdom", "Germany", "Switzerland", "United Kingdom", "Israel", "United Kingdom", "Lithuania", "Poland"], "Project_ACR": ["MAESTRO"], "Technology_Description": "The European Training Network MAESTRO (MAking pErovskiteS TRuly explOitable) will generate new skills, knowledge and innovation in the exploitation of perovskite materials in solar power and efficient lighting through establishing exploitation paths for perovskite devices in an integrated unitary approach. MAESTRO is an intersectoral and multidisciplinary network of 10 academic and 7 industrial beneficiaries from 8 EU and Associated countries, including 2 countries in the EU-13. It focusses on perovskite semiconductors, a material shown in the last 4 years to have a major impact on solar power and potentially also in display technology. Our research aims to make perovskite based devices commercially viable. MAESTRO offers broad skills development and experience of cross sector research to 15 Early Stage Researchers, ESRs. Training is provided in (i) science and technology across physics, chemistry, materials science, electrical engineering, in two major application areas, solar cells and light emitting diodes, and other uses such as lasers and photodiodes; (ii) exploitation from laboratory to fabrication; (iii) transferable skills of communication, information technology, organization, planning, teamwork, leadership; (iv) skills needed for innovation, such as understanding markets, product life cycles, business models, return on investment. Gender aspects are addressed through supervisors, mentors and training. The research undertaken by MAESTRO will teach the ESRs how to deal with complexities and uncertainties, making them very broad and highly adaptable. Their PhDs will position them to be comfortable in both corporate and academic worlds. They will be able to seek careers that are rewarding professionally and financially, through career paths in self-employment, finance, consultancy, contracting, engineering, computer science, production", "To": ["2021-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Chiara Andreoli", "Tel.: +3901071781854", "Fax: +39 010 7170817", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-11-01"], "Project_ID": ["764787"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK", "UNIVERSIDADE DO MINHO", "UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA", "JACOBS UNIVERSITY BREMEN GGMBH", "UNIVERSITY OF LEICESTER", "INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE"], "EU_Contribution": ["EUR 3 094 944,48"], "Project_Title": ["Yeast Biotechnology Doctoral Training Programme"], "Total_Cost": ["EUR 3 094 944,48"], "Country": ["Ireland", "Portugal", "Italy", "Germany", "United Kingdom", "France"], "Project_ACR": ["YEASTDOC"], "Technology_Description": "YEASTDOC is a European Joint Doctoral programme to train researchers for outstanding careers as leaders in the field of yeast biotechnology. Six academic institutions are joined by 7 industry and 2 training partner organisations to offer an international training programme leading to the award of joint PhD degrees. The interdisciplinary, trans-sectoral research topic takes advantage of recent technological developments to link fundamental research in yeasts with new applications in the beverage and white biotechnology sectors. 12 Early Stage Researchers will each carry out a 36-month joint PhD project between two academic institutions, spending at least 12 months at each partner university in a different European country. All projects include an industry co-supervisor from a partner organisation and ESRs have an industry secondment of 4-6 months to gain intersectoral experience. Additional research training is provided via summer schools, scientific conferences, doctoral seminars and practical workshops. Further training in innovation-related skills will be provided through network-wide courses that include technology transfer management and entrepreneurship. Transferrable skills training is delivered locally in graduate schools and by network courses in responsible research and innovation, scientific writing, and research leadership. ESRs will disseminate research outcomes in the scientific sector and will participate in outreach activities to engage targeted public audiences in research. All training will receive ECTS credits and be mutually recognised by all academic partners. A joint governance and ESR monitoring structure, including external experts, will assure the quality of the training programme. The long-term impact of the EJD will be an accredited, sustainable, inter-institutional doctoral programme that delivers high quality PhD graduates to drive research and innovation to maintain competitiveness in European biotechnology.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EJD - European Joint Doctorates"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["764927"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU", "CENTRE EUROPEEN DE RECHERCHE ET DE FORMATION AVANCEE EN CALCUL SCIENTIFIQUE", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "TECHNISCHE UNIVERSITAET MUENCHEN", "TECHNISCHE UNIVERSITAET BERLIN", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "SAFRAN SA", "SAFRAN HELICOPTER ENGINES", "ANSALDO ENERGIA SWITZERLAND AG"], "EU_Contribution": ["EUR 3 974 482,80"], "Project_Title": ["Annular Instabilities and Transient Phenomena in Gas Turbine Combustors"], "Total_Cost": ["EUR 3 974 482,80"], "Country": ["Norway", "France", "France", "Germany", "Germany", "United Kingdom", "Switzerland", "France", "France", "Switzerland"], "Project_ACR": ["ANNULIGhT"], "Technology_Description": "The gas turbine industry is a vital driver of innovation, economic growth, jobs, trade and mobility in the EU in both the aviation and power generation sectors. It is a multi-billion Euro high-technology industry whose future competitiveness depends on a new generation of creative engineers with multi-disciplinary skills who can accelerate the development of new innovations needed for flexible, efficient power generation and sustainable aviation.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-10-01"], "Project_ID": ["765998"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["ERASMUS UNIVERSITEIT ROTTERDAM", "INSTITUTE OF DEVELOPMENT STUDIES", "UNIVERSITAT PASSAU", "FREIE UNIVERSITAET BERLIN", "HUMBOLDT-UNIVERSITAET ZU BERLIN", "WAGENINGEN UNIVERSITY", "UNIVERSITY OF BRIGHTON", "SVERIGES LANTBRUKSUNIVERSITET", "STICHTING IHE DELFT", "FONDAZIONE PANGEA ONLUS"], "EU_Contribution": ["EUR 3 872 823,12"], "Project_Title": ["Well-being, Ecology, Gender, and cOmmunity"], "Total_Cost": ["EUR 3 872 823,12"], "Country": ["Netherlands", "United Kingdom", "Germany", "Germany", "Germany", "Netherlands", "United Kingdom", "Sweden", "Netherlands", "Italy"], "Project_ACR": ["WEGO"], "Technology_Description": "WEGO (Well-being, Ecology, Gender and cOmmunity) is a trans-national network aims to develop a shared research and training agenda to educate the next generation of interdisciplinary social-environmental scientists on feminist political ecology in Europe. WeGO\u2019s research examines gender relations in community organizing from a feminist-informed political ecology (FPE) framework. From an international and interdisciplinary perspective, WEGO looks at gender and power relations in community responses to the current climate, economic and environmental crises in different socio-ecological contexts. WEGO aims to provide insightful and compelling analysis about the importance of gendered community response to climate, economic and environmental change as well as more detailed knowledge about what changes are required for greater resilience and sustainability. Gender is understood as a critical variable in shaping resource access and control, interacting with class, caste, race, culture, and ethnicity to shape processes of ecological change and the prospects of any community for sustainable development. WEGO research will look at resilience and sustainability by examining the gendered role of women in care work for the community and for the environment. The cases chosen \u2013 from in and outside of Europe are sites that can feed into innovative European Policy on sustainable development.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Other"], "From": ["2018-01-01"], "Project_ID": ["764908"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["UNIVERSITEIT GENT", "HELSINGIN YLIOPISTO", "AALTO-KORKEAKOULUSAATIO", "UNIVERSITETET I OSLO", "Asociacion - Centro de Investigacion Cooperativa en Nanociencias - CIC NANOGUNE", "NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO", "UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK", "INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM", "RUHR-UNIVERSITAET BOCHUM", "KATHOLIEKE UNIVERSITEIT LEUVEN"], "EU_Contribution": ["EUR 3 898 797,84"], "Project_Title": ["A European Training Network for Functional Hybrid Coatings by Molecular Layer Deposition"], "Total_Cost": ["EUR 3 898 797,84"], "Country": ["Belgium", "Finland", "Finland", "Norway", "Spain", "Netherlands", "Ireland", "Belgium", "Germany", "Belgium"], "Project_ACR": ["HYCOAT"], "Technology_Description": "HYCOAT is the first ETN at the intersection of chemistry, physics, materials science and engineering dealing with the synthesis and applications of hybrid coatings grown by molecular layer deposition (MLD). With self-limiting binary reactions, MLD is the ideal ultra-thin film deposition technique, offering unique advantages for growing uniform, conformal hybrid films providing precise and flexible control over the film thickness and chemical composition at molecular scale. This new field of MLD is pioneered at nanoscience laboratories across Europe. HYCOAT provides a European approach to facilitate an interdisciplinary and multi-environment (Universities, Research Centers, SMEs & Large industries) platform for training a new generation of MLD researchers. A coordinated effort of 10 beneficiaries and 16 partner organizations from 7 European countries (Belgium, Finland, Germany, Ireland, Netherlands, Norway and Spain), HYCOAT targets the development of novel precursor chemistries, processes, characterisation and modelling of MLD and the demonstration of hybrid coatings in four key high impact fields of application relevant for European industries, in packaging, biomedical, electronics and batteries. Understanding and engineering of hybrid coatings by MLD is essential for its wide range of applications and the interaction with European high-tech industry is ensured through the active participation of 10 industries, 2 university hospitals and a synchrotron facility. Training will take place through research projects, courses and workshops, with the emphasis on self-directed, hands-on, collaborative learning. This European knowledge alliance with an inter- and trans-disciplinary mobility and an intense collaboration between the private and public entities is needed to equip the next generation of researchers and extrapolate Europe\u2019s current pioneering role in the science of MLD towards a leadership in economic and societal impact of innovations enabled by MLD.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["765378"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["UNIVERSITE DE BORDEAUX", "ECOLE NATIONALE SUPERIEURE DES MINES DE PARIS", "ECOLE NATIONALE D'INGENIEURS DE TARBES", "LULEA TEKNISKA UNIVERSITET", "UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA", "BCAM - BASQUE CENTER FOR APPLIED MATHEMATICS", "FUNDACION TECNALIA RESEARCH & INNOVATION", "SAFRAN SA", "SIRRIS HET COLLECTIEF CENTRUM VAN DE TECHNOLOGISCHE INDUSTRIE"], "EU_Contribution": ["EUR 2 316 282,12"], "Project_Title": ["European Network for Alloys Behaviour Law Enhancement"], "Total_Cost": ["EUR 2 316 282,12"], "Country": ["France", "France", "France", "Sweden", "Spain", "Spain", "Spain", "France", "Belgium"], "Project_ACR": ["ENABLE"], "Technology_Description": "ENABLE aims to train early-stage researchers in what is referred to as an outstanding challenge for the future of manufacturing: developing novel solutions for forecasting and mastering processes relevant for all factories using metallic alloys. ", "To": ["2022-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations"], "From": ["2018-02-01"], "Project_ID": ["764979"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Evolution of cell fate decision during development"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["EvoCellFate"], "Technology_Description": "\"During development cells progressively acquire specific features that result in the definition of cellular fates.Inter- and intra-specific homologous cell lineages show significant variation in the adoption of particular cell fates. Yet, at present the genetic and molecular mechanisms underlying these intra-specific changes in cell fate and how variation in cell fates is biased during evolutionary trajectories are largely unknown. In this project I will use the vulva system in genetically tractable nematodes to i)identify the molecular basis of intraspecific cell fate variation and ii)to investigate whether evolutionary trajectories in cell fate variation are developmentally constrained in distinct nematode genera. In Caenorhabditis species, among the six \"\"vulva precursor cells\"\", only one termed P3.p shows fate evolution within and among species.In contrast,in Oscheius species(sister genus)other vulva precursor cells fates evolve faster, named P4.p and P8.p. The work is structured into two main objectives. First,I will investigate the molecular and genetic basis of intraspecific P3.p cell fate variation in C.elegans using quantitative genetics, whole-genome sequencing and modern genome editing techniques. Second,I will probe the role of developmental constrains in biasing evolutionary trends of cell fate variation by using a combination of random mutagenesis and quantitative genetics.This project will contribute to integrate the field of evolution of development with a population and quantitative genetic framework and will provide a mechanistic genetic understanding of cell fate variation during development and evolution at several evolutionary scales. Based on a highly successful research group in a worldwide-recognized institute and its network of collaborators,it will allow me to obtain a strong background in evolutionary theory,nematode development,genome bioinformatic skills and quantitative genetics,building on my strong molecular and developmental background\"", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2017-11-01"], "Project_ID": ["751530"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF SUSSEX"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Restart of blocked replication fork at replication fork barrier"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["Rep. Fork Restart"], "Technology_Description": "Errors in replication of DNA lead to serious diseases like cancer, inherited neurological and muscular diseases. Replication is constantly challenged by various obstacles that can result in error-prone replication. Replication fork barriers (RFBs) include proteins bound to DNA, structure forming sequences and DNA/RNA hybrids. Replication forks (RFs) stalled or blocked at these barriers can be rescued by a converging fork. But if this fails blocked RF must be restarted to complete replication. Restart using homologous recombination (HR) can lead to gross chromosomal rearrangements and copy number variations. The newly restarted replication fork is also prone to slippage leading to mutation and rearrangements. ", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["749631"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM", "UNIVERSITEIT MAASTRICHT", "THE UNIVERSITY OF READING", "LEIBNIZ-INSTITUT FUR ANALYTISCHE WISSENSCHAFTEN-ISAS-EV", "UNIVERSITAETSKLINIKUM WUERZBURG - KLINIKUM DER BAYERISCHEN JULIUS-MAXIMILIANS-UNIVERSITAT", "ALACRIS THERANOSTICS GMBH", "UNIVERSIDAD DE SANTIAGO DE COMPOSTELA"], "EU_Contribution": ["EUR 3 881 891,88"], "Project_Title": ["TArgeting Platelet Adhesion receptors in thrombosiS"], "Total_Cost": ["EUR 3 881 891,88"], "Country": ["United Kingdom", "Netherlands", "United Kingdom", "Germany", "Germany", "Germany", "Spain"], "Project_ACR": ["TAPAS"], "Technology_Description": "TAPAS will position Europe at the forefront of innovative research to prevent thrombosis and thromboinflammation, and will train a uniquely-qualified cohort of ESRs in a highly intersectorial and multi-disciplinary programme that will equip them with the knowledge and transferable skills required in the broad biomedical sector. The research will focus on platelets which are small cells in the blood that play a critical role in prevention of excessive bleeding following injury (haemostasis). Activation of platelets in diseased vessels gives rise to thrombotic disorders such as heart attack and stroke, two of the major causes of morbidity and mortality. Patients at risk of thrombosis are treated with medicines that inhibit platelets for life, but many patients still undergo thrombotic episodes or encounter serious bleeds through diminished haemostasis. There is thus an urgent need for novel and safe anti-platelet medicines that powerfully target thrombosis but preserve haemostasis. In TAPAS, an original and innovative approach will be undertaken to find new ways to target thrombosis through co-operation of academic experts in distinct disciplines with key skills from the private sector. TAPAS will generate and integrate knowledge from analytical complex \u2018omics\u2019, advanced microscopy, cell biology, microfluidics, in vivo models, contemporary systems biology and high throughput screens to identify new targets for therapeutic intervention and novel lead compounds or biologics. The research skills developed in this programme are applicable to other complex diseases and represent essential training in modern day research for the next cohort of academic and private sector scientists that are able to convert complex biological understanding into new medicines. The shared knowledge and close interaction between beneficiaries and partners makes this programme ideally suited to an EJD and will deliver 15 ESRs in 21st century biomedical research.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EJD - European Joint Doctorates"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["766118"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["THE UNIVERSITY OF SHEFFIELD", "UNIVERSITY OF DURHAM", "CHALMERS TEKNISKA HOEGSKOLA AB", "RANPLAN WIRELESS NETWORK DESIGN LTD", "TELEVIC CONFERENCE", "GAPWAVES AB", "UNIVERSITAT POLITECNICA DE VALENCIA"], "EU_Contribution": ["EUR 2 880 995,40"], "Project_Title": ["mmWave Communications in the Built Environments"], "Total_Cost": ["EUR 2 880 995,40"], "Country": ["United Kingdom", "United Kingdom", "Sweden", "United Kingdom", "Belgium", "Sweden", "Spain"], "Project_ACR": ["WAVECOMBE"], "Technology_Description": "The foreseen exponential growth of mobile data traffic will not be uniform across geographical areas, but is mainly concentrated in hot spots that are usually located in the built environments (BEs) such as central business districts, stations, airports, stadiums, dense urban environments, etc. This poses considerable challenges that we believe can be solved by ultra dense deployment of millimetre-wave (mmW) small-cells (SCs) in conjunction with massive multiple-input multipleoutput (MIMO) in 5G and beyond 5G (B5G) wireless networks. However, there are a number of research challenges that need to be addressed for a successful deployment of 5G/B5G wireless networks: even if the theoretical background of massive MIMO is by now rather complete, the actual performance characterization and measurements of mmW antenna arrays has not yet been fully addressed at either the component or system level; mmW radio channel measurements have been performed but with limited time delay resolution, single antennas and over single radio links; and mmW bands have been considered for mobile communications, but the level of detail and diversity of BEs necessary for meaningful mmW SC deployment has not been fully exploited. Therefore, we propose here a research approach that combines the three disruptive key enabling technologies for 5G/B5G with the aim to answer fundamental questions that are still not well understood. ", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["766231"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN", "THE UNIVERSITY OF MANCHESTER", "VRIJE UNIVERSITEIT BRUSSEL", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "FONDAZIONE EDMUND MACH", "INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE", "UNIVERSIDAD DE ZARAGOZA", "LALLEMAND SAS", "SINGER INSTRUMENT COMPANY LIMITED", "NOVOZYMES A/S"], "EU_Contribution": ["EUR 3 684 848,76"], "Project_Title": ["Generation of new yeast strains for improved flavours and aromas in beer and wine"], "Total_Cost": ["EUR 3 684 848,76"], "Country": ["Ireland", "United Kingdom", "Belgium", "Spain", "Italy", "France", "Spain", "France", "United Kingdom", "Denmark"], "Project_ACR": ["Aromagenesis"], "Technology_Description": "This project aims to train the next generation of researchers to provide knowledge and expertise for two major industries in the EU, namely the beer and wine industries. Yeasts belonging to the Saccharomyces stricto sensu group are the workhorses of these industries and an understanding of how yeasts contribute to the complex flavours and aromas of beer and wine is essential for the improvement of existing fermentation technology and for the development new flavoursome beverages.", "To": ["2021-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-12-01"], "Project_ID": ["764364"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["UNIVERSITETET I OSLO"], "EU_Contribution": ["EUR 208 400,40"], "Project_Title": ["Interfaces for Relational Listening: body, telematics, memory, migration"], "Total_Cost": ["EUR 208 400,40"], "Country": ["Norway"], "Project_ACR": ["INTIMAL"], "Technology_Description": "In the European context of migration and diasporas, and at the intersection of sound art, music cognition, psychology and human-computer interaction, this project will develop INTIMAL: a novel physical-virtual \u201cembodied system\u201d for relational listening. Through the artistic practice of telematic sonic performance this system will interconnect people\u2019s bodily motion and voice with their memories and dreams of distant locations. ", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["752884"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["NATIONAL UNIVERSITY OF IRELAND GALWAY"], "EU_Contribution": ["EUR 248 063,40"], "Project_Title": ["Carabids as biocontrol agents for slugs in Oregon and Ireland - a novel and interdisciplinary approach to determine key malacophagous species and beneficial management options"], "Total_Cost": ["EUR 248 063,40"], "Country": ["Ireland"], "Project_ACR": ["CaraSlug"], "Technology_Description": "One of the challenges identified under Horizon 2020 is the building of a sustainable agri-food industry. Agricultural pests such as slugs are major contributors to financial losses in the farming sector and the use of pesticides, which is currently the mainstay of control, is an unsustainable management option due to their toxicity to non-target species and consumers but also because of their cost and variable efficacy. Biocontrol poses a more sustainable approach to pest control, but the only commercially available agent against slugs is the nematode Phasmarhabditis hermaphrodita which is ineffective against a number of key pest species, has a short shell life and is not permitted in countries outside of Europe (e.g. USA). CaraSlug aims to assess the potential of native carabid species as biocontrol agents against slug pests in Oregon and Ireland. For the first time, high-throughput sequencing and real-time PCR will be used in combination to analyse the gut contents of carabids collected over one year from vulnerable crops. Carabid species which are found to feed extensively on slugs and are abundant in crops at times when major slug damage occurs will be selected for feeding trials in the laboratory to further understand their feeding behaviour and biocontrol potential. By comparing the abundance of both pest and predator species and by determining the availability of alternative prey in differently managed crops e.g. with and without beetle banks over a year, management systems which provide optimum conditions for malacophagous carabid species will be identified. This project is interdisciplinary, combining \u2018classic\u2019 ecology and environmental management approaches with the latest advances in molecular biology and both the experienced researcher and the hosts will benefit greatly from the combined team\u2019s expertise. By directly involving farmers in our research, this project will also form an important link between academia and the community.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["750296"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["NATIONAL UNIVERSITY OF IRELAND GALWAY"], "EU_Contribution": ["EUR 187 866"], "Project_Title": ["Treatment of contaminated land using a biochar/media mixture"], "Total_Cost": ["EUR 187 866"], "Country": ["Ireland"], "Project_ACR": ["TOOLBOX"], "Technology_Description": "Waste disposal and treatment is a major source of contamination of soils, surface and groundwater, and accounts for 35% of the 1.1 million contaminated sites in Europe. Leaching of the organic solvent trichloroethylene (TCE) into groundwater has been identified as a primary issue with unlined landfills , affecting up to 70% of leachates tested. Mainly used as a metal degreaser and dry-cleaning reagent, TCE is difficult to treat; current treatment methods, such as anaerobic digestion or air stripping , are ineffective and/or expensive. This project will investigate the use biochar, or other appropriate media, for treatment of TCE contaminated water via two technologies - permeable reactive interceptors (PRIs) and permeable contaminant retaining filter (PCRF) bags. This novel, low-cost solution will address the requirements of European Union (EU) legislation, including the Water Framework Directive (WFD). The project will be based at the National University of Ireland, Galway (NUIG) with supervision by Dr Mark Healy (GeoEnvironmental Engineering Research Group \u2013 GENE) and support from Dr Florence Abram (Functional Environmental Microbiology - FEM). As the applicant has experience in TCE treatment from a microbial background, this highly novel, interdisciplinary proposal will compliment and strengthen her existing skillset by approaching this technology from an engineering perspective, with support from a research group that has a strong track record in this research area. With detailed career development assistance, multiple opportunities to further her strong publication record, access to numerous and varied fora for dissemination of results and support for IP exploitation, this proposal will have a significant impact in reintegrating the applicant back into the EU research community from her current research position in New Zealand.", "To": ["2019-07-09, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-10"], "Project_ID": ["748106"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF SUSSEX"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Quantum Sensing with Quantum Optical Networks"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["QUSON"], "Technology_Description": "Quantum sensing exploits effects such as entanglement to enhance the sensitivity of measurement devices. In the last decade we have witnessed a significant advance in experimental platforms such as trapped ion setups and superconducting circuits. These systems are never free from noise and dissipation, however, interactions between qubits and photons or phonons can be controlled with lasers or external fields. Even in strong dissipative regimes, cooperative effects may induce complex quantum dynamics with emergent phenomena such as non-equilibrium phase transitions and multistability. The question then arises whether we can exploit those many-body effects in robust metrological protocols. ", "To": ["2020-06-03, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-06-04"], "Project_ID": ["752180"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITETET I OSLO"], "EU_Contribution": ["EUR 208 400,40"], "Project_Title": ["Deciphering the mycobiome of indoor environments by high-throughput sequencing"], "Total_Cost": ["EUR 208 400,40"], "Country": ["Norway"], "Project_ACR": ["MycoIndoor"], "Technology_Description": "Fungi have ubiquitous distribution in natural ecosystems and are also common in the built environment, where people spend major parts of their lifetime. When moisture is present, fungal growth can cause material deterioration and adverse effects on the occupant\u2019s health. Traditional methods for analyzing the indoor mycobiome, such as culturing and microscopy, have severe limitations.", "To": ["2020-02-29, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["741332"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE GRENOBLE ALPES", "UNIVERSITY OF LEEDS", "EUROPEAN SPALLATION SOURCE ERIC", "AARHUS UNIVERSITET", "THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN", "UNIVERSITAET HAMBURG", "NATIONAL UNIVERSITY OF IRELAND MAYNOOTH", "UNIVERSITY OF SURREY", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE"], "EU_Contribution": ["EUR 3 243 291,48"], "Project_Title": ["RAtionalising Membrane Protein crystallisation"], "Total_Cost": ["EUR 3 243 291,48"], "Country": ["France", "United Kingdom", "Sweden", "Denmark", "Ireland", "Germany", "Ireland", "United Kingdom", "United Kingdom"], "Project_ACR": ["RAMP"], "Technology_Description": "Membrane proteins form more than 85% of drug targets, but just 600 unique membrane protein crystal structures have been determined. A better understanding of how to crystallize membrane proteins reliably is therefore urgently required. The Innovative Training Network \u201cRAtionalising Membrane Protein crystallisation\u201d \u2013 RAMP will bring together cutting-edge physical chemistry methods for crystallisation condition control and phase diagram exploration, and the development of new lipids and screens in conjunction with industry with the most challenging biological problems. The network includes expert academic and industrial research groups in crystallisation theory, methods development, membrane protein crystallography, drug development and novel structural techniques like time-resolved and neutron crystallography. We will develop new, rational methods for crystallising membrane proteins, focusing particularly on transporters that are also interesting drug targets. The new robust crystallisation methods will also allow us to use emerging European research infrastructures like XFEL or ESS to gain insight into membrane protein function because the techniques will provide the necessary precise control of crystal size. ", "To": ["2021-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-03-01"], "Project_ID": ["722687"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["CONSIGLIO NAZIONALE DELLE RICERCHE", "Koninklijk Instituut voor het Kunstpatrimonium", "THE CYPRUS INSTITUTE", "USTAV TEORETICKE A APLIKOVANE MECHANIKY AVCR", "DEUTSCHES ARCHAOLOGISCHES INSTITUT", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "CONSORCIO PARA LA CONSTRUCCION, EQUIPAMIENTO Y EXPLOTACION DEL CENTRO NACIONAL DE INVESTIGACION SOBRE LA EVOLUCION HUMANA", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "DIGITAL RESEARCH INFRASTRUCTURE FOR THE ARTS AND HUMANITIES", "FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS", "Magyar Tudomanyos Akademia Atommagkutato Intezete", "THE DISCOVERY PROGRAMME : CENTRE FOR ARCHAEOLOGY AND INNOVATION IRELAND", "Israel Antiquities Authority", "CENTRAL EUROPEAN RESEARCH INFRASTRUCTURE CONSORTIUM EUROPEAN RESEARCH INFRASTRUCTURE CONSORTIUM", "PIN SOC.CONS. A R.L. - SERVIZI DIDATTICI E SCIENTIFICI PER L UNIVERSITA DI FIRENZE", "MINISTERIE VAN ONDERWIJS, CULTUUR EN WETENSCHAP", "UNIWERSYTET MIKOLAJA KOPERNIKA W TORUNIU", "LABORATORIO NACIONAL DE ENGENHARIA CIVIL", "JAVNI ZAVOD REPUBLIKE SLOVENIJE ZA VARSTVO KULTURNE DEDISCINE", "UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 3 999 449"], "Project_Title": ["The European Research Infrastructure for Heritage Science Preparatory Phase"], "Total_Cost": ["EUR 3 999 449"], "Country": ["Italy", "Belgium", "Cyprus", "Czech Republic", "Germany", "Spain", "Spain", "France", "France", "Greece", "Hungary", "Ireland", "Israel", "Italy", "Italy", "Netherlands", "Poland", "Portugal", "Slovenia", "United Kingdom"], "Project_ACR": ["E-RIHS PP"], "Technology_Description": "E-RIHS PP is a coordination and support action addressing the topic \u201cPreparatory Phase and support to early phase of ESFRI projects\u201d within the call H2020-INFRADEV-02-2016. The specific action addressed by this project is the preparation of E-RIHS, the European Research Infrastructure for Heritage Science (HS), one of the six new projects which entered the ESFRI Roadmap in 2016, and the only research infrastructure project in the Social and Cultural Innovation section of the Roadmap. E-RIHS will help the preservation of the World\u2019s Heritage by enabling cutting-edge research in HS, liaising with governments and heritage institutions to promote its constant development and, finally, raising the appreciation of the large public for cultural and natural heritage and the recognition of its historic, social and economic significance.", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["INFRADEV-02-2016 - Preparatory Phase and support to early phase of ESFRI projects"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2017-02-01"], "Project_ID": ["739503"], "Call_for_Proposal": ["H2020-INFRADEV-2016-2"]}, -{"Partners": ["THE UNIVERSITY OF SUSSEX"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Zebrafish colour vision: a functional approach to studying outer retinal wiring strategies"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ColourFish"], "Technology_Description": "Colour vision is critical animals to navigate their environment. Here, two or more spectrally distinct cone-photoreceptor types are needed in the retina which must be postsynaptically combined to extract contrasts in wavelength.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["748716"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF SUSSEX"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Representing Idiocy and Intellectual Disability in Early Modern English Literature, 1500-1640"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["Renaissance Idiocy"], "Technology_Description": "My project will consider several examples of natural or artificial fools, clowns, idiots portrayed in the literary production of England from 1500 to 1640 and will investigate how early modern notions of intellectual deficiency primarily in medicine but also in society shaped the creation of those same figures. My literary corpus will include not only dramatic texts but also jestbooks, which notably offer a wealth of information on real or fantastic fools of the time, and poetical works. Folly in the sense of lack of wit, rather than the loss of it \u2013 which is the definition of madness \u2013 will be my primary focus. While the theme of madness in connection with early modern literature has been explored at length, the same cannot be said for cognitive disability or lack of intelligence. The main reason for this is that only recently have a small number of scholars started to discuss and bring together historical, medical and legal notions of natural folly in the early modern period. In the past, remarkable attempts at historicizing natural folly have bordered into discourses on madness and analogue mental disorders thus blurring the difference between the two conditions, the same difference that Renaissance legislation actually sought to define. In the wake of very recent trends in disability studies, therefore, I will use legal but especially medical theories of foolishness and idiocy to explore the characters of my corpus and to highlight, on a scientific and social basis, their separate nature from those conceived of as lunatics. Furthermore, because the exploration of intellectual disability in my period of interest is relatively a new field, I expect to find in the fools of my corpus hints to theories or assumptions that have not been discussed yet.", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["745642"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITETET I OSLO"], "EU_Contribution": ["EUR 196 400,40"], "Project_Title": ["Images in Exile:Gender and representations among Syrian Kurdish women in Norway"], "Total_Cost": ["EUR 196 400,40"], "Country": ["Norway"], "Project_ACR": ["IMEX"], "Technology_Description": "The project Images in Exile (IMEX) addresses the current refugee crisis and its implications for Syrian Kurdish women in Europe. It challenges images about Muslim women, who are often the subject of debates on the supposed dichotomy between an imagined secular progressive West and religious backwards East. Kurdish women disrupt this dichotomy through an alternative portrayal in global media. Whereas Kurds were previously often pictured as terrorists, backward, and conservative, they are now presented as courageous fighters against, and victims of, Islamic terrorism; and as progressive forces that include women in their ranks. Ideas about progressive, feminist and secular forms of governance are strongly developed in Kurdish political thought, and central in local self-representations.", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-03-01"], "Project_ID": ["753935"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITETET I OSLO"], "EU_Contribution": ["EUR 196 400,40"], "Project_Title": ["Functional dissection of the head-direction circuit in mouse retrosplenial cortex."], "Total_Cost": ["EUR 196 400,40"], "Country": ["Norway"], "Project_ACR": ["RSCHD"], "Technology_Description": "Head direction (HD) cells provide directional information during spatial navigation and thus act as an", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-03-01"], "Project_ID": ["753608"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITETET I OSLO"], "EU_Contribution": ["EUR 196 400,40"], "Project_Title": ["The evolutionary origins and consequences of human-commensalism in Passer sparrows"], "Total_Cost": ["EUR 196 400,40"], "Country": ["Norway"], "Project_ACR": ["EVOSPARROW"], "Technology_Description": "Human-commensal species are almost constantly present in our daily lives; they are the mice in our fields or the sparrows in our gardens. The evolutionary trajectories of these species are intertwined with our own through the development of agriculture and human civilization, yet we know surprisingly little about their origins. ", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["748299"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITETET I OSLO"], "EU_Contribution": ["EUR 208 400,40"], "Project_Title": ["Linking micro- and macroevolution: macroevolutionary quantitative genetics of Drosophila wing morhology"], "Total_Cost": ["EUR 208 400,40"], "Country": ["Norway"], "Project_ACR": ["FLYWING"], "Technology_Description": "The striking mismatch between evolution at short (microevolution) and long (macroevolution) time scales is a major remaining problem in evolutionary biology (the paradox of stasis). FLYWING will apply novel quantitative genetic theories and statistical methods to analyses of exceptionally high quality data to make a major step forward to solve the paradox of stasis.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["747338"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["INSTITUTO DE MEDICINA MOLECULAR", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE UNIVERSITY OF SUSSEX", "WEIZMANN INSTITUTE OF SCIENCE", "FONDAZIONE TELETHON", "INSTITUTUL DE BIOCHIMIE", "Lipotype GmbH", "GENOMED, DIAGNOSTICOS DE MEDICINA MOLECULAR SA", "PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE", "UNIVERSIDAD DE BUENOS AIRES", "THE CHILDREN'S HOSPITAL OF PHILADELPHIA NON PROFIT ORG"], "EU_Contribution": ["EUR 1 102 500"], "Project_Title": ["Genetic and Small Molecule Modifiers of Lysosomal Function"], "Total_Cost": ["EUR 1 156 500"], "Country": ["Portugal", "United Kingdom", "United Kingdom", "Israel", "Italy", "Romania", "Germany", "Portugal", "Chile", "Argentina", "United States"], "Project_ACR": ["LysoMod"], "Technology_Description": "LysoMod will innovate in the area of personalized medicine for disorders linked to lysosomal dysfunction. This will be achieved by implementing a collaborative staff-exchange program between highly complementary and multidisciplinary academic and non-academic partners with expertise in pharmacology, medicinal chemistry, cell biology, biochemistry, mouse and human genetics, transcriptomics, proteomics and lipidomics. Based on the critical role that lysosomes play in cells, a better understanding of lysosomal function will have a major impact on human health, fostering the development of new strategies to improve quality of life for people affected by a variety of diseases, ranging from lysosomal storage diseases (LSDs) to age-related neurodegenerative disorders. LysoMod\u2019s specific objectives are: 1) to develop and further optimize existing therapies for LSDs; 2) to identify new targets for personalized therapies for LSDs; and 3) to investigate the cross-talk between lysosomal function, signalling pathways and gene expression regulation. The pioneer work of a participant in the consortium led to the development of a drug that is approved for clinical use. LysoMod will i) investigate the mechanisms of action of this and other drugs in lysosome-related disorder; ii) identify modifier genes involved in LSD pathology and test their potential as new targets for personalized therapeutic approaches; iii) identify candidate RNAs that can be targeted to enhance lysosomal function. The companies in the consortium will ensure a rapid transfer of new knowledge into applications for diagnostics and clinical trials. Prioritising lysosomal dysfunction as a highly relevant biomedical problem, the LysoMod consortium will implement a mentored staff-exchange program to provide young researchers with high-level training in innovative approaches for exploring biological systems, preparing the next generation of researchers for careers either in the private or public health sectors.", "To": ["2021-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Portugal"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other"], "From": ["2017-03-01"], "Project_ID": ["734825"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSITY OF LEEDS", "Asociacion - Centro de Investigacion Cooperativa en Nanociencias - CIC NANOGUNE", "RAITH GMBH", "CHALMERS TEKNISKA HOEGSKOLA AB", "UNIVERSITAT KONSTANZ", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "GRAPHENEA SA", "AALTO-KORKEAKOULUSAATIO"], "EU_Contribution": ["EUR 3 884 019,12"], "Project_Title": ["QUantum Electronics Science and TECHnology training"], "Total_Cost": ["EUR 3 884 019,12"], "Country": ["France", "United Kingdom", "Spain", "Germany", "Sweden", "Germany", "Switzerland", "Spain", "Finland"], "Project_ACR": ["QuESTech"], "Technology_Description": "Quantum Electronics provides a challenging and innovative multidisciplinary framework for training young researchers with excellent prospects for a career either in the industry or in academia. In this promising area, the \u201cQuantum Electronics Science and Technology training\u201d project, with acronym QuESTech, will create a European network of experts providing state-of-the-art training for young researchers in the general field of experimental, applied and theoretical Quantum Electronics.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["766025"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["NATIONAL UNIVERSITY OF IRELAND GALWAY"], "EU_Contribution": ["EUR 175 866"], "Project_Title": ["Novel, highly effective and selective anticancer metallodrugs"], "Total_Cost": ["EUR 175 866"], "Country": ["Ireland"], "Project_ACR": ["TSPO METALLODRUGS"], "Technology_Description": "Dr. Leila Tabrizi, an Iranian national, is making an application to this programme to carry out a 24 months project in the area of medicinal chemistry in the group of Dr. A. Erxleben at the National University of Ireland, Galway.", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["749621"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAET KASSEL", "AARHUS UNIVERSITET", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "IBM RESEARCH GMBH", "INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE", "NVISION IMAGING TECHNOLOGIES GMBH", "TTI-Technologie-Transfer-Initiative GmbH", "TECHNISCHE UNIVERSITAET MUENCHEN", "TECHNISCHE UNIVERSITAET WIEN", "UNIVERSITAT DES SAARLANDES", "UNIVERSITAET ULM", "THALES SA", "COMMUNAUTE D' UNIVERSITES ET ETABLISSEMENTS UNIVERSITE BOURGOGNE - FRANCHE - COMTE"], "EU_Contribution": ["EUR 3 881 935,42"], "Project_Title": ["Quantum-enhanced Sensing via Quantum Control"], "Total_Cost": ["EUR 3 881 935,42"], "Country": ["Germany", "Denmark", "France", "France", "Switzerland", "France", "Germany", "Germany", "Germany", "Austria", "Germany", "Germany", "France", "France"], "Project_ACR": ["QuSCo"], "Technology_Description": "Quantum technologies aim to exploit quantum coherence and entanglement, the two essential elements of quantum physics. Successful implementation of quantum technologies faces the challenge to preserve the relevant nonclassical features at the level of device operation. It is thus deeply linked to the ability to control open quantum systems. The currently closest to market quantum technologies are quantum communication and quantum sensing. The latter holds the promise of reaching unprecedented sensitivity, with the potential to revolutionize medical imaging or structure determination in biology or the controlled construction of novel quantum materials. Quantum control manipulates dynamical processes at the atomic or molecular scale by means of specially tailored external electromagnetic fields. The purpose of QuSCo is to demonstrate the enabling capability of quantum control for quantum sensing and quantum measurement, advancing this field by systematic use of quantum control methods. QuSCo will establish quantum control as a vital part for progress in quantum technologies.", "To": ["2021-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Corinna Hahn", "Tel.: +49 681 95 92 3362", "Fax: +49 681 95 92 3370", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["765267"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["OTTO-FRIEDRICH-UNIVERSITAET BAMBERG", "COPENHAGEN BUSINESS SCHOOL", "CRANFIELD UNIVERSITY", "INSTITUT FUER ARBEITSMARKT- UND BERUFSFORSCHUNG (IAB) DER BUNDESAGENTUR FUER ARBEIT", "TOULOUSE BUSINESS SCHOOL -TBS", "VAASAN YLIOPISTO", "STICHTING VU", "AIRBUS SAS"], "EU_Contribution": ["EUR 3 947 612,40"], "Project_Title": ["Global mobility of employees"], "Total_Cost": ["EUR 3 947 612,40"], "Country": ["Germany", "Denmark", "United Kingdom", "Germany", "France", "Finland", "Netherlands", "France"], "Project_ACR": ["GLOMO"], "Technology_Description": "Promoting labour mobility across Europe is a central objective of the Europe 2020 Strategy and it aims to tackle increasing labour and skill shortages in the EU. Cross-border labour mobility is expected to benefit both individual citizens, employers and the aggregate economy. In addition, intra-EU mobility is a means to foster European integration. Although migration into OECD countries increases, driven largely by people moving within the EU, migration into and within Europe is still short of target levels. Despite a favourable legal framework for mobility, migrants still face a wide range of problems and obstacles that hamper cross-border labour mobility. Employment prospects for immigrants are below those of natives and overqualification, i.e. employment below skill levels, is widespread in most European countries. Consequently, the growth potential of immigrants is far from realised. Little is known about transnational mobility patterns and the length of migration episodes as well as about retention processes of foreign employees. There is considerable scope to make existing labour mobility more efficient and beneficial for all parties involved.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Other", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-01-01"], "Project_ID": ["765355"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["INSTITUTE OF DEVELOPMENT STUDIES", "INSTITUTE OF DEVELOPMENT STUDIES", "EUROPEAN UNIVERSITY INSTITUTE"], "EU_Contribution": ["EUR 2 499 126,50"], "Project_Title": ["Pastoralism, Uncertainty and Resilience: Global Lessons from the Margins"], "Total_Cost": ["EUR 2 499 126,50"], "Country": ["United Kingdom", "United Kingdom", "Italy"], "Project_ACR": ["PASTRES"], "Technology_Description": "Existing institutions, legal frameworks and governance systems are not equipped to respond to growing global uncertainties and the challenges of building resilience. Radical new thinking is needed. Important lessons potentially can come from surprising quarters. Drawing insights from pastoral areas across three continents, we will ask: What lessons can we learn from pastoral systems responding to rapid change that help us understand how to live with uncertainty and build resilience? Learning from the margins \u2013 through a reversal in conventional policy learning and debate - this project will draw out principles from deeply-embedded, culturally-rich responses to rapid change and uncertainty in pastoral areas in Africa (Borana, Ethiopia), Asia (Qinghai-Tibet, China) and Europe (Sardinia, Italy). ", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["740342"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["GRAND ACCELERATEUR NATIONAL D'IONS LOURDS", "ISTITUTO NAZIONALE DI FISICA NUCLEARE", "EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH", "JYVASKYLAN YLIOPISTO", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "GSI HELMHOLTZZENTRUM FUER SCHWERIONENFORSCHUNG Gmbh", "RIJKSUNIVERSITEIT GRONINGEN", "THE HENRYK NIEWODNICZANSKI INSTITUTE OF NUCLEAR PHYSICS, POLISH ACADEMY OF SCIENCES", "UNIWERSYTET WARSZAWSKI", "\"INSTITUTUL NATIONAL DE CERCETARE -DEZVOLTARE PENTRU FIZICA SI INGINERIE NUCLEARA \"\"HORIA HULUBEI\"\" (IFIN-HH)\"", "FONDAZIONE BRUNO KESSLER", "EBG (Entwicklungs- und Betriebsgesellschaft) MedAustron GmbH", "KATHOLIEKE UNIVERSITEIT LEUVEN", "UNIVERSITE LIBRE DE BRUXELLES", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "GROUPEMENT INTERET PUBLIC ARRONAX", "JUSTUS-LIEBIG-UNIVERSITAET GIESSEN", "JOHANNES GUTENBERG-UNIVERSITAT MAINZ", "LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN", "UNIVERSITAET ZU KOELN", "\"NATIONAL CENTER FOR SCIENTIFIC RESEARCH \"\"DEMOKRITOS\"\"\"", "UNIVERSITA DEGLI STUDI DI MILANO", "FUNDACAO DA FACULDADE DE CIENCIAS DA UNIVERSIDADE DE LISBOA FP", "CENTRO DE INVESTIGACIONES ENERGETICAS, MEDIOAMBIENTALES Y TECNOLOGICAS-CIEMAT", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "UNIVERSIDAD DE SANTIAGO DE COMPOSTELA", "UNIVERSIDAD DE SEVILLA", "THE UNIVERSITY OF LIVERPOOL", "UNIVERSITY OF YORK", "Magyar Tudomanyos Akademia Atommagkutato Intezete"], "EU_Contribution": ["EUR 10 000 000"], "Project_Title": ["European Nuclear Science and Application Research 2"], "Total_Cost": ["EUR 10 000 000"], "Country": ["France", "Italy", "Switzerland", "Finland", "France", "Germany", "Netherlands", "Poland", "Poland", "Romania", "Italy", "Austria", "Belgium", "Belgium", "France", "France", "Germany", "Germany", "Germany", "Germany", "Greece", "Italy", "Portugal", "Spain", "Spain", "Spain", "Spain", "United Kingdom", "United Kingdom", "Hungary"], "Project_ACR": ["ENSAR2"], "Technology_Description": "ENSAR2 is the integrating activity for European nuclear scientists who are performing research in three of the major subfields defined by NuPECC: Nuclear Structure and Dynamics, Nuclear Astrophysics and Nuclear Physics Tools and Applications. It proposes an optimised ensemble of Networking (NAs), Joint Research (JRAs) and Transnational Access Activities (TAs), which will ensure qualitative and quantitative improvement of the access provided by the current ten infrastructures, which are at the core of this proposal. The novel and innovative developments that will be achieved by the RTD activities will also assure state-of-the-art technology needed for the new large-scale projects.", "To": ["2020-02-29, ongoing project"], "Meta": [""], "Topic_s": ["INFRAIA-1-2014-2015 - Integrating and opening existing national and regional research infrastructures of European interest"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["654002"], "Call_for_Proposal": ["H2020-INFRAIA-2014-2015"]}, -{"Partners": ["HELSINGIN YLIOPISTO", "HELSINGIN YLIOPISTO"], "EU_Contribution": ["EUR 1 999 987"], "Project_Title": ["Gene knock-up via 3\u2019UTR targeting to treat Parkinson\u2019s disease"], "Total_Cost": ["EUR 1 999 987"], "Country": ["Finland", "Finland"], "Project_ACR": ["PD UpReg"], "Technology_Description": "Parkinson\u2019s disease (PD) affects 1% of elderly persons and is currently incurable. PD pathogenesis is driven, at least in part, by defects in proteostasis and mitochondrial function, leading to degeneration of dopaminergic axons and neuronal death. Neurotrophic factors (NTFs) such as GDNF can protect and restore dopaminergic axons. However, attempts to deploy NTFs ectopically in therapy models, or to increase proteostasis and mitochondrial function, have met with only limited success.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["724922"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["Institute of Science and Technology Austria", "Institute of Science and Technology Austria"], "EU_Contribution": ["EUR 2 410 292"], "Project_Title": ["Tracing Evolution of Auxin Transport and Polarity in Plants"], "Total_Cost": ["EUR 2 410 292"], "Country": ["Austria", "Austria"], "Project_ACR": ["ETAP"], "Technology_Description": "Multicellularity in plants evolved independently from other eukaryotes and presents a unique, alternative way how to deal with challenges of life. A major plant developmental module is the directional transport for the plant hormone auxin. The crucial components are PIN auxin transporters, whose polar, subcellular localization determines directionality of auxin flow through tissues. PIN-dependent auxin transport represents a unique model for studying the functional link between basic cellular processes, such as vesicle trafficking and cell polarity, and their developmental outcome at the level of the multicellular organism. Despite decades of intensive research, the classical approaches in the established models are approaching their limits and many crucial questions remain unsolved, in particular related to PIN structure, regulatory motifs and evolutionary origin ", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["742985"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITETET I OSLO", "UNIVERSITETET I OSLO"], "EU_Contribution": ["EUR 2 499 961"], "Project_Title": ["Scalable inference algorithms for Bayesian evolutionary epidemiology"], "Total_Cost": ["EUR 2 499 961"], "Country": ["Norway", "Norway"], "Project_ACR": ["SCARABEE"], "Technology_Description": "Advances in sequencing technologies are currently providing an unprecedented opportunity to a detailed discovery of the mechanisms involved in the evolution and spread of microbes causing human infectious disease. Simultaneously the developers of statistical methods face an enormous challenge to cope with the wealth of data brought by this opportunity. We have very recently demonstrated the ability of our advanced computational approaches to deliver breakthroughs in understanding pathogen evolution and transmission in numerous highlight results published in Science, PNAS and top-ranking Nature journals. The rise of microbial Big Data gives a promise of a giant leap in making causal discoveries, however, the existing statistical methods are neither able to cope with the size and complexity of the emerging data sets nor designed to answer the novel biological questions they enable. To fulfil the promise of giant leaps SCARABEE will leverage scalable inference methods by a unique combination of machine learning algorithms and Bayesian statistical models for evolutionary epidemiology. We focus on central biological questions about adaptation, epistasis, genome evolution and transmission of microbes causing infectious disease. The Big Data combined with the novel inference methods will make it possible to answer a multitude of important questions that remain currently intractable. Through our close collaboration with the leading research centres in infectious disease epidemiology and genomics we expect the SCARABEE project to considerably advance understanding of the evolution and transmission of numerous pathogens that pose a major threat to human health, which will be important for reducing their disease burden in the future. Large-scale biological data will be used to benchmark the developed methods, which will be made publicly available as free software packages to benefit the wide community of microbiologists and infectious disease epidemiologists.", "To": ["2022-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["742158"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSIDAD DE ZARAGOZA", "UNIVERSIDAD DE ZARAGOZA"], "EU_Contribution": ["EUR 2 483 136"], "Project_Title": ["Catalytic Dual-Function Devices Against Cancer"], "Total_Cost": ["EUR 2 483 136"], "Country": ["Spain", "Spain"], "Project_ACR": ["CADENCE"], "Technology_Description": "Despite intense research efforts in almost every branch of the natural sciences, cancer continues to be one of the leading causes of death worldwide. It is thus remarkable that little or no therapeutic use has been made of a whole discipline, heterogeneous catalysis, which is noted for its specificity and for enabling chemical reactions in otherwise passive environments. At least in part, this could be attributed to practical difficulties: the selective delivery of a catalyst to a tumour and the remote activation of its catalytic function only after it has reached its target are highly challenging objectives. Only recently, the necessary tools to overcome these problems seem within reach.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["742684"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITETET I OSLO", "UNIVERSITETET I OSLO"], "EU_Contribution": ["EUR 1 990 213"], "Project_Title": ["Abiota, Biota, Constraints in Macroevolutionary Processes"], "Total_Cost": ["EUR 1 990 213"], "Country": ["Norway", "Norway"], "Project_ACR": ["macroevolution.abc"], "Technology_Description": "To what degree do microevolutionary processes that happen on a generational time scale matter for macroevolutionary patterns recorded on time scales of millions of years in the fossil record? To answer this fundamental question in evolutionary biology, we need a model system in which we can overcome the conceptual and empirical boundaries imposed by disparate timescales. macroevolution.abc will develop bryozoans as the Drosophila of macroevolution, integrating molecular, fossil, phenotypic, ecological and environmental data to shed light on the currently inaccessible \u201cDark Time Scale\u201d (thousands, to tens of thousands of years), spanning the chasm between microevolution studied by population geneticists and evolutionary ecologists and macroevolution studied by paleontologists and comparative phylogeneticists. Using bryozoans, a little-known but uniquely ideal study group for evolutionary questions, I will generate, then cross-integrate, (i) empirical time series of intra- and interspecific biotic interactions; (ii) phenotypic data describing variation within genetic individuals, variation among contemporaneous individuals in both extinct and living populations; (iii) robust estimates of abundance shifts in fossil populations; and (iv) speciation and extinction rate estimates from molecular phylogenies and the fossil record. The new bryozoan model evolutionary system will provide answers to previously intractable questions such as \u201cdo ecological interactions crucial for individual survival matter for group diversification patterns observed on geological time scales\u201d and \u201cwhy do we have to wait a million years for bursts of phenotypic change\u201d?", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["724324"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "AALTO-KORKEAKOULUSAATIO", "ACADEMISCH ZIEKENHUIS LEIDEN", "ATHENS UNIVERSITY OF ECONOMICS AND BUSINESS - RESEARCH CENTER", "BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION", "BAUHAUS-UNIVERSITAET WEIMAR", "BERGISCHE UNIVERSITAET WUPPERTAL", "Bloomfield Science Museum Jerusalem (BSMJ)", "CARDIFF UNIVERSITY", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "CONSIGLIO NAZIONALE DELLE RICERCHE", "CINECA CONSORZIO INTERUNIVERSITARIO", "DANMARKS TEKNISKE UNIVERSITET", "DEBRECENI EGYETEM", "DE MONTFORT UNIVERSITY", "ECOLE NORMALE SUPERIEURE", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "FONDEN TEKNOLOGIRADET", "FORSCHUNGSZENTRUM JULICH GMBH", "FORTISS GMBH", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.", "FUNDACAO D. ANNA SOMMER CHAMPALIMAUD E DR. CARLOS MONTEZ CHAMPALIMAUD", "HEINRICH-HEINE-UNIVERSITAET DUESSELDORF", "HELSINGIN YLIOPISTO", "HITS GGMBH", "CENTRE HOSPITALIER UNIVERSITAIRE VAUDOIS", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "Institut du Cerveau et de la Moelle \u00e9pini\u00e8re", "INSTITUTE OF EXPERIMENTAL MEDICINE - HUNGARIAN ACADEMY OF SCIENCES", "Institute of Science and Technology Austria", "INSTITUT JOZEF STEFAN", "INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE", "INSTITUT PASTEUR", "JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN", "KARLSRUHER INSTITUT FUER TECHNOLOGIE", "KAROLINSKA INSTITUTET", "KING'S COLLEGE LONDON", "KUNGLIGA TEKNISKA HOEGSKOLAN", "LABORATORIO EUROPEO DI SPETTROSCOPIE NON LINEARI", "LINNEUNIVERSITETET", "MEDIZINISCHE UNIVERSITAT INNSBRUCK", "ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON", "NORGES MILJO-OG BIOVITENSKAPLIGE UNIVERSITET", "OSTERREICHISCHE STUDIENGESELLSCHAFTFUR KYBERNETIK VEREIN", "RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN", "RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG", "SABANCI UNIVERSITESI", "SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO SANT'ANNA", "STICHTING CENTRUM VOOR WISKUNDE EN INFORMATICA", "STICHTING KATHOLIEKE UNIVERSITEIT", "STIFTUNG FZI FORSCHUNGSZENTRUM INFORMATIK AM KARLSRUHER INSTITUT FUR TECHNOLOGIE", "THE RESEARCH COMMITTEE OF THE TECHNICAL UNIVERSITY OF CRETE", "TECHNISCHE UNIVERSITAET DRESDEN", "TECHNISCHE UNIVERSITAET GRAZ", "TECHNISCHE UNIVERSITAET MUENCHEN", "TEL AVIV UNIVERSITY", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE HEBREW UNIVERSITY OF JERUSALEM", "THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN", "THE UNIVERSITY OF EDINBURGH", "THE UNIVERSITY OF MANCHESTER", "UNIVERSIDAD AUTONOMA DE MADRID", "UNIVERSIDAD DE CASTILLA - LA MANCHA", "UNIVERSIDAD DE GRANADA", "UNIVERSIDADE DO MINHO", "UNIVERSIDAD POLITECNICA DE MADRID", "UNIVERSIDAD REY JUAN CARLOS", "UNIVERSITA DEGLI STUDI DI PAVIA", "UNIVERSITAET BERN", "UNIVERSITAET BIELEFELD", "UNIVERSITAETSKLINIKUM AACHEN", "UNIVERSITAETSKLINIKUM HAMBURG-EPPENDORF", "UNIVERSITAT ZURICH", "UNIVERSITAT DE BARCELONA", "UNIVERSIDAD POMPEU FABRA", "UNIVERSITE D'AIX MARSEILLE", "UNIVERSITE DE BORDEAUX", "UNIVERSITEIT ANTWERPEN", "UNIVERSITETET I OSLO", "UNIVERSITY COLLEGE LONDON", "UPPSALA UNIVERSITET", "WEIZMANN INSTITUTE OF SCIENCE", "TECHNISCHE UNIVERSITAT DARMSTADT", "UNIVERSITE DE GENEVE", "UNIVERSITY OF GLASGOW", "MEDICAL RESEARCH COUNCIL", "UNIVERSITAET HAMBURG", "HUMBOLDT-UNIVERSITAET ZU BERLIN", "KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW", "ISTITUTO NAZIONALE DI FISICA NUCLEARE", "CONSORCI INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER", "UNIVERSITA DEGLI STUDI DI MILANO", "FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA", "ISTITUTO SUPERIORE DI SANITA", "UNIVERSITE DE LIEGE", "UNIVERSITEIT VAN AMSTERDAM", "DEUTSCHES ZENTRUM FUR NEURODEGENERATIVE ERKRANKUNGEN EV", "THE UNIVERSITY OF SHEFFIELD", "UNIVERSITY OF THE WEST OF ENGLAND, BRISTOL", "UNIVERSITY OF SURREY", "TTY-SAATIO", "UNIVERSITY OF LEEDS", "UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6", "THE UNIVERSITY OF SUSSEX", "MIDDLESEX UNIVERSITY HIGHER EDUCATION CORPORATION", "UNIVERSITE LYON 1 CLAUDE BERNARD", "POLITECNICO DI TORINO", "UNIVERSITEIT GENT", "KATHOLIEKE UNIVERSITEIT LEUVEN", "UNIVERSITAET BASEL", "STICHTING VU", "SWISS INSTITUTE OF BIOINFORMATICS", "EUROPEAN BRAIN RESEARCH INSTITUTE R ITA LEVI-MONTALCINI FONDAZIONE*EBRI", "SCUOLA NORMALE SUPERIORE", "UNIVERSITEIT MAASTRICHT", "THE UNIVERSITY OF HERTFORDSHIRE HIGHER EDUCATION CORPORATION"], "EU_Contribution": ["EUR 89 000 000"], "Project_Title": ["Human Brain Project Specific Grant Agreement 1"], "Total_Cost": ["EUR 89 000 000"], "Country": ["Switzerland", "Finland", "Netherlands", "Greece", "Spain", "Germany", "Germany", "Israel", "United Kingdom", "France", "France", "Italy", "Italy", "Denmark", "Hungary", "United Kingdom", "France", "Switzerland", "Denmark", "Germany", "Germany", "Germany", "Portugal", "Germany", "Finland", "Germany", "Switzerland", "United Kingdom", "France", "Hungary", "Austria", "Slovenia", "France", "France", "Germany", "Germany", "Sweden", "United Kingdom", "Sweden", "Italy", "Sweden", "Austria", "Greece", "Norway", "Austria", "Germany", "Germany", "Turkey", "Italy", "Netherlands", "Netherlands", "Germany", "Greece", "Germany", "Austria", "Germany", "Israel", "United Kingdom", "Israel", "United Kingdom", "United Kingdom", "United Kingdom", "Spain", "Spain", "Spain", "Portugal", "Spain", "Spain", "Italy", "Switzerland", "Germany", "Germany", "Germany", "Switzerland", "Spain", "Spain", "France", "France", "Belgium", "Norway", "United Kingdom", "Sweden", "Israel", "Germany", "Switzerland", "United Kingdom", "United Kingdom", "Germany", "Germany", "Netherlands", "Italy", "Spain", "Italy", "Spain", "Italy", "Belgium", "Netherlands", "Germany", "United Kingdom", "United Kingdom", "United Kingdom", "Finland", "United Kingdom", "France", "United Kingdom", "United Kingdom", "France", "Italy", "Belgium", "Belgium", "Switzerland", "Netherlands", "Switzerland", "Italy", "Italy", "Netherlands", "United Kingdom"], "Project_ACR": ["HBP SGA1"], "Technology_Description": "Understanding the human brain is one of the greatest scientific challenges of our time. Such an understanding can provide profound insights into our humanity, leading to fundamentally new computing technologies, and transforming the diagnosis and treatment of brain disorders. Modern ICT brings this prospect within reach. The HBP Flagship Initiative (HBP) thus proposes a unique strategy that uses ICT to integrate neuroscience data from around the world, to develop a unified multi-level understanding of the brain and diseases, and ultimately to emulate its computational capabilities. The goal is to catalyze a global collaborative effort. During the HBP\u2019s first Specific Grant Agreement (SGA1), the HBP Core Project will outline the basis for building and operating a tightly integrated Research Infrastructure, providing HBP researchers and the scientific Community with unique resources and capabilities. Partnering Projects will enable independent research groups to expand the capabilities of the HBP Platforms, in order to use them to address otherwise intractable problems in neuroscience, computing and medicine in the future. In addition, collaborations with other national, European and international initiatives will create synergies, maximizing returns on research investment. SGA1 covers the detailed steps that will be taken to move the HBP closer to achieving its ambitious Flagship Objectives.", "To": ["2018-03-31, ongoing project"], "Meta": [""], "Topic_s": ["FETFLAGSHIP - FETFLAGSHIP"], "Funding_scheme": ["SGA-RIA - SGA-RIA"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-04-01"], "Project_ID": ["720270"], "Call_for_Proposal": ["H2020-Adhoc-2014-20"]}, -{"Partners": ["NATIONAL UNIVERSITY OF IRELAND GALWAY", "NATIONAL UNIVERSITY OF IRELAND GALWAY"], "EU_Contribution": ["EUR 149 954"], "Project_Title": ["Challenging Hypertension Through Novel Medical Device Development"], "Total_Cost": ["EUR 149 954"], "Country": ["Ireland", "Ireland"], "Project_ACR": ["REALTA"], "Technology_Description": "Hypertension directly causes approximately 25% of heart attacks in Europe and, in its progressed form of cardiovascular disease, it is estimated to cause 42% of all deaths across Europe annually. Untreated hypertension is one of the primary contributors to a number of the medical conditions with the greatest burden of care, including stroke, dementia and kidney failure. One of the most promising avenues for the treatment of hypertension has been research into primary aldosteronism (PA). In the last ten years, PA has been recognised as the most common curable cause of hypertension. PA is thought to account for up to 18% of all cases of hypertension within the population and is caused by benign shallow adenomas on the surface of the adrenal gland. Researchers have identified the effective treatment of PA as a clear mechanism to address Europe\u2019s hypertension problem. However, finding an effective surgical or pharmaceutical treatment for PA has been challenging to date. ", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["754308"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["UNIVERSITY OF EAST ANGLIA", "UNIVERSITY OF EAST ANGLIA"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Getting to the root of ageing: somatic decay as a cost of germline maintenance"], "Total_Cost": ["EUR 2 000 000"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["GermlineAgeingSoma"], "Technology_Description": "The trade-off between survival and reproduction lies at the core of the evolutionary theory of ageing. Removal of germ cells extends somatic lifespan implying that reduced reproduction frees up resources for survival. Remarkably, however, the disruption of germline signalling increases lifespan without the obligatory reduction in fecundity, thus challenging the key role of the survival-reproduction trade-off. Recent breakthroughs suggest that protection and repair of the genome and the proteome of the germ cells is costly and compromised germline maintenance increases mutation rate, which can reduce offspring fitness. Thus, expensive germline maintenance can be a missing link in the puzzle of cost-free lifespan extension. This hypothesis predicts that when germline signalling is manipulated to increase investment into somatic cells, the germline maintenance will suffer resulting in increased mutation rate and reduced offspring fitness, even if total fecundity is unaffected. I propose a research program at the interface of evolutionary biology and biogerontology that focuses on phenotypic and evolutionary costs of germline maintenance. First, I will genetically manipulate germline signalling to boost investment into soma and estimate mutation rate and competitive fitness of the resulting offspring using Caenorhabditis elegans nematodes. Second, I will employ experimental evolution in nematodes to assess the long-term evolutionary costs of increased germline maintenance. Third, I will use germline transplantation in zebrafish Dario rerio to directly test whether germline proliferation reduces investment into soma in a vertebrate. Understanding how increased investment into the soma damages the germline and reduces offspring fitness will provide a major advance in our understanding of ageing evolution and will have serious implications for applied research programs aimed at harnessing the power of germline signalling to postpone ageing.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["724909"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["THE UNIVERSITY OF SUSSEX", "THE UNIVERSITY OF SUSSEX"], "EU_Contribution": ["EUR 1 999 390"], "Project_Title": ["Violence Elites and Resilience in States Under Stress"], "Total_Cost": ["EUR 1 999 390"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["VERSUS"], "Technology_Description": "Political violence affects 2 billion citizens across the developing world. Conflict contributes to political decline, high corruption and poverty, poor social cohesion and low institutional trust. VERSUS represents a new direction in political, geographic and empirical subnational studies of conflict and governance. It determines how violence erupts from political processes in varied environments and examines how common internal and external shocks create new trajectories of governance, violence and potential for political resilience. It argues that political relationships between subnational elites and regimes incentivise political violence in developing states. Through a suite of multi-and-mixed methods including power mapping, extensive elite interviews, Bayesian spatial models and dynamic network innovations, VERSUS creates multiple real-time measures of power distribution across select African, Middle Eastern and Asian states for widespread research and policy use. It has five objectives: to advance a developing paradigm on subnational political architectures and environments over static institutionalism; to generate several measures of comparative political power distributions in developing states that capture the degree and depth of regime and elite relationships; to design and test scenarios to explain how, when and where violence erupts as a strategic function of architectures and environments; to develop and implement novel conflict \u2018resilience\u2019 tests of regimes, elites and vulnerable members of society in response to internal and external shocks. This creates a state\u2019s \u2018carrying capacity\u2019 for shocks and violence; and finally, to collaborate with development practitioners and civil society to implement new standards for elite transparency, support for human rights and \u2018good governance\u2019 outcomes.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["726504"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITAET ZU KOELN", "UNIVERSITAET ZU KOELN"], "EU_Contribution": ["EUR 2 406 250"], "Project_Title": ["Majorana Fermions in Topological Insulator Platforms"], "Total_Cost": ["EUR 2 406 250"], "Country": ["Germany", "Germany"], "Project_ACR": ["MajoranaTopIn"], "Technology_Description": "Majorana fermions were recently discovered in topological superconductors as exotic quasiparticles having the curious property of being their own antiparticles. They are not only interesting as novel relativistic quasiparticles, but are also useful for realizing fault-tolerant quantum computers. However, currently available platforms to materialize Majorana fermions are limited, and the existing platforms have respective drawbacks for actually building qubits for a scalable quantum computer. Also, various unusual properties are predicted for Majorana fermions, but few have been experimentally addressed. To make a leap in the Majorana-fermion research which is technically highly demanding, one needs to grow state-of-the-art materials and tightly combine them with mesoscopic device research. By performing such an integrated research efforts in the same laboratory, this project aims to explore new platforms for Majorana qubits and to establish new methodologies to address peculiar physics of Majorana fermions. As new platforms, we pursue (i) three-dimensional topological-insulator nanoribbons and (ii) ferromagnetic topological-insulator thin films, both of which will be proximity-coupled to an s-wave superconductor. Each of them allows for conceiving Majorana qubits based on different principles, which will be tested in this project. Also, by developing new methodologies, we will elucidate (i) non-Abelian statistics probed by interferometry and (ii) quantized/universal heat transport phenomena probed by thermal conductance. These works will be complemented by materials growth efforts involving molecular beam epitaxy and detailed characterizations of the local electronic states using scanning tunnelling spectroscopy. If successful, this project will not only contribute to the realization of scalable quantum computers, but also elucidate the non-Abelian statistics, which is a fundamentally new property of particles and is ground breaking in physics.", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["741121"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["THE UNIVERSITY OF SUSSEX", "THE UNIVERSITY OF SUSSEX"], "EU_Contribution": ["EUR 1 979 270"], "Project_Title": ["Time-Resolved Nonlinear Ghost Imaging"], "Total_Cost": ["EUR 1 979 270"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["TIMING"], "Technology_Description": "This project addresses major challenges in Terahertz (THz) sensing at the forefront of the experimental and theoretical investigation. The results will have far-reaching implications in complex science. They will target the next generation of THz imagers, acknowledged as unique diagnostic tools in cross-disciplinary fields in light of the THz\u2019s distinctive ability to unambiguously discriminate molecular compounds.", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["725046"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["CINECA CONSORZIO INTERUNIVERSITARIO", "THE UNIVERSITY OF EDINBURGH", "BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION", "UNIVERSITAET STUTTGART", "SURFSARA BV", "CSC-TIETEEN TIETOTEKNIIKAN KESKUS OY", "ETHNIKO DIKTYO EREVNAS TECHNOLOGIAS AE", "KUNGLIGA TEKNISKA HOEGSKOLAN", "NATIONAL UNIVERSITY OF IRELAND GALWAY", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 9 206 161,50"], "Project_Title": ["Transnational Access Programme for a Pan-European Network of HPC Research Infrastructures and Laboratories for scientific computing"], "Total_Cost": ["EUR 9 216 248,59"], "Country": ["Italy", "United Kingdom", "Spain", "Germany", "Netherlands", "Finland", "Greece", "Sweden", "Ireland", "France"], "Project_ACR": ["HPC-EUROPA3"], "Technology_Description": "HPC-Europa3 aims at maintaining the persistency of a high quality service of transnational access to the most advanced HPC infrastructures available in Europe for the European research science community. European researchers could rely on the existence of such transnational access activity for almost two decades, and the main aim of this new innovative 3rd edition of HPC-Europa series is to fill the gap left in the four years since the end of the last initiative has ended. ", "To": ["2021-04-30, ongoing project"], "Meta": [""], "Topic_s": ["INFRAIA-01-2016-2017 - Integrating Activities for Advanced Communities"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2017-05-01"], "Project_ID": ["730897"], "Call_for_Proposal": ["H2020-INFRAIA-2016-1"]}, -{"Partners": ["UNIVERSITETET I OSLO", "UNIVERSITETET I OSLO"], "EU_Contribution": ["EUR 1 999 481,75"], "Project_Title": ["The Missing Link of Episodic Memory Decline in Aging: The Role of Inefficient Systems Consolidation"], "Total_Cost": ["EUR 1 999 481,75"], "Country": ["Norway", "Norway"], "Project_ACR": ["AgeConsolidate"], "Technology_Description": "Which brain mechanisms are responsible for the faith of the memories we make with age, whether they wither or stay, and in what form? Episodic memory function does decline with age. While this decline can have multiple causes, research has focused almost entirely on encoding and retrieval processes, largely ignoring a third critical process\u2013 consolidation. The objective of AgeConsolidate is to provide this missing link, by combining novel experimental cognitive paradigms with neuroimaging in a longitudinal large-scale attempt to directly test how age-related changes in consolidation processes in the brain impact episodic memory decline. The ambitious aims of the present proposal are two-fold: ", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["725025"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["KATHOLIEKE UNIVERSITEIT LEUVEN", "TARKI Tarsadalomkutatasi Intezet Zrt", "UNIVERSITEIT VAN AMSTERDAM", "STOCKHOLMS UNIVERSITET", "UNIVERSITAT TRIER", "CENTRE D ESTUDIS DEMOGRAFICS", "LISER - LUXEMBOURG INSTITUTE OF SOCIO-ECONOMIC RESEARCH", "UNIVERSITEIT ANTWERPEN", "UNIVERSITY OF ESSEX", "DEUTSCHES INSTITUT FUR WIRTSCHAFTSFORSCHUNG DIW (INSTITUT FUR KONJUNKTURFORSCHUNG) EV", "CONSERVATOIRE NATIONAL DES ARTS ET METIERS", "CENTRE FOR EUROPEAN POLICY STUDIES", "UNIVERSITA DI PISA", "UNIVERSITY OF SOUTHAMPTON", "Luxembourg Income Study, asbl", "THE UNIVERSITY OF MANCHESTER", "STREDOEUROPSKY INSTITUT PRE VYSKUMPRACE ZDRUZENIE", "PANTEIO PANEPISTIMIO KOINONIKON KAIPOLITIKON EPISTIMON", "CENTRALNY INSTYTUT OCHRONY PRACY - PANSTWOWY INSTYTUT BADAWCZY"], "EU_Contribution": ["EUR 9 345 420,50"], "Project_Title": ["Integrating Research Infrastructure for European expertise on Inclusive Growth from data to policy"], "Total_Cost": ["EUR 9 345 420,50"], "Country": ["Belgium", "Hungary", "Netherlands", "Sweden", "Germany", "Spain", "Luxembourg", "Belgium", "United Kingdom", "Germany", "France", "Belgium", "Italy", "United Kingdom", "Luxembourg", "United Kingdom", "Slovakia", "Greece", "Poland"], "Project_ACR": ["InGRID-2"], "Technology_Description": "Referring to the increasingly challenging EU2020-ambitions of Inclusive Growth , the objectives of the InGRID-2 project are to advance the integration and innovation of distributed social sciences research infrastructures (RI) on \u2018povety, living conditions and social policies\u2019 as well as \u2018working conditions, vulnerability and labour policies\u2019. InGRID-2 will extend transnational on-site and virtual access, organize mutual learning and discussions of innovations, and improve data services and facilities of comparative research. The focus areas are a) integrated and harmonized data, (b) links between policy and practice, and (c) indicator-building tools.", "To": ["2021-04-30, ongoing project"], "Meta": [""], "Topic_s": ["INFRAIA-01-2016-2017 - Integrating Activities for Advanced Communities"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Other", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2017-05-01"], "Project_ID": ["730998"], "Call_for_Proposal": ["H2020-INFRAIA-2016-1"]}, -{"Partners": ["UNIVERSITY OF CENTRAL LANCASHIRE", "UNIVERSITY OF CENTRAL LANCASHIRE", "DOLPHIO TECHNOLOGIES INFORMATIKAI KORLATOLT FELELOSSEGU TARSASAG"], "EU_Contribution": ["EUR 149 723"], "Project_Title": ["Multilingual work spaces for sign language users \u2013 An online portal driving social innovation"], "Total_Cost": ["EUR 149 723"], "Country": ["United Kingdom", "United Kingdom", "Hungary"], "Project_ACR": ["SIGNSPACE"], "Technology_Description": "This project aims to pilot a social innovation by translating some of the findings of the ERC-funded MULTISIGN project (\u201cMultilingual behaviours in sign language users\u201d) into an online portal which promotes and facilitates transnational communication by deaf people through sign languages. The portal provides activities to users that increase their meta-linguistic awareness about the bi- and multilingual use of sign languages. Specifically, we will exploit research data and analyses by translating them into a resource with educational units that support upskilling of deaf people in order to communicate remotely with signers of other sign languages. The MULTSIGN project had demonstrated that sign language users have a unique enhanced potential, compared to spoken languages, to communicate across language boundaries, and the project will enable signers to exploit this potential. The portal also provides a service for setting up flexibly adaptable bi- and multilingual online work spaces for transnational groups of sign language users, with an integrated tool for sign-to-sign-translation between different sign languages. This will enable disadvantaged deaf communities, who are largely isolated from international contact, to access developments and resources already available elsewhere among international deaf communities but not linguistically accessible. The project is a collaboration between an academic partner, the University of Central Lancashire (UCLan) in the UK and a private company with special expertise in the relevant area, Dolphio Technologies, in Hungary. Our joint team will develop the design and test the technical infrastructure for the project. We will conduct demonstration, training and piloting workshops in several countries, and develop a business plan for further development and sustainability of the portal based on its marketable potential.", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-04-01"], "Project_ID": ["737587"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["INSTRUCT ACADEMIC SERVICES LIMITED", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "VIB", "Masarykova univerzita", "JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN", "AARHUS UNIVERSITET", "ETHNIKO IDRYMA EREVNON", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "OULUN YLIOPISTO", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "WEIZMANN INSTITUTE OF SCIENCE", "CONSORZIO INTERUNIVERSITARIO RISONANZE MAGNETICHE DI METALLO PROTEINE", "UNIVERSITEIT UTRECHT", "UNIVERSIDADE NOVA DE LISBOA", "INSTITUTO DE TECNOLOGIA QUIMICA E BIOLOGICA - UNIVERSIDADE NOVA DE LISBOA", "KAROLINSKA INSTITUTET", "CHEMICKY USTAV SLOVENSKEJ AKADEMIEVIED"], "EU_Contribution": ["EUR 3 950 000"], "Project_Title": ["Releasing the full potential of Instruct to expand and consolidate infrastructure services for integrated structural life science research"], "Total_Cost": ["EUR 3 950 000"], "Country": ["United Kingdom", "United Kingdom", "Belgium", "Czech Republic", "Germany", "Denmark", "Greece", "Spain", "Finland", "France", "Israel", "Italy", "Netherlands", "Portugal", "Portugal", "Sweden", "Slovakia"], "Project_ACR": ["INSTRUCT-ULTRA"], "Technology_Description": "Instruct-Ultra aims to advance the scope and efficiency of implementation of Instruct and consolidate the foundations for long-term sustainability. This will be achieved through specific objectives: expand Instruct membership to new Member States and increase global links; engage new user communities; improve efficiencies in service delivery; improve data capture and management; adjust the scale and reliability of the infrastructure. Instruct-Ultra will deliver these alongside the transition to ERIC legal status and rapid developments in, and increased demand for, integrated structural biology infrastructure. These advances in the scale and speed of delivery will earn further trust within the life science community. One focus will to expand membership to Eastern European states and EFTA countries, integrating their structural biology communities into Instruct and providing new opportunities to support research excellence and raise standards. Opportunities for engaging with industrialised and developing countries outside the ERA will build on existing cooperative work between Instruct and Asian, African and South American countries to establish strong bilateral programmes of benefit to both parties, giving Instruct better engagement in emerging global challenges and positioning Instruct as a trusted global resource for high quality structural biology services. Starting from baseline operations four years ago Instruct has now identified key areas of service which should be expanded, new potential user groups, and opportunities for more reliable, efficient and sometimes remotely used workflows. Instruct-Ultra will therefore test new modes of access and pilot new service methods in high demand areas to accelerate access for more users. Instruct-Ultra will reinforce Instruct operations by updating and expanding the business plan and structural biology roadmap, whilst improving the interface with academia and industry as a strategy to sustainability.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["INFRADEV-03-2016-2017 - Individual support to ESFRI and other world-class research infrastructures"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["United Kingdom"], "Activity": ["Other", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2017-01-01"], "Project_ID": ["731005"], "Call_for_Proposal": ["H2020-INFRADEV-2016-1"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "THE UNIVERSITY OF SUSSEX"], "EU_Contribution": ["EUR 1 347 992"], "Project_Title": ["Screening for cancer in the post-genomic era: diagnostic innovation and biomedicalisation in comparative perspective"], "Total_Cost": ["EUR 1 347 992"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom"], "Project_ACR": ["CANCERSCREEN"], "Technology_Description": "Cancer screening and the diagnostics industry: a comparative analysis of the political economy of diagnostic innovation.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["716689"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["UNIVERSITA CA' FOSCARI VENEZIA", "UNIVERSITA CA' FOSCARI VENEZIA", "EESTI KIRJANDUSMUUSEUM"], "EU_Contribution": ["EUR 1 496 675"], "Project_Title": ["Ethnobotany of divided generations in the context of centralization"], "Total_Cost": ["EUR 1 496 675"], "Country": ["Italy", "Italy", "Estonia"], "Project_ACR": ["DiGe"], "Technology_Description": "Understanding the logics of obtaining, managing and perceiving of local natural resources, particularly plants, is crucial for ensuring sustainability of human life, as the use of plants is a key for survival of humans. The proposed research will create an advanced understanding of the mechanisms of changes in ethnobotanical knowledge experienced by traditional societies/minor ethnic groups when dominating group try to unify and/or erode this practical knowledge. It will also evaluate the effects of the sudden cease to existence of such centralization and following impact of the trial of revival of discontinued traditional etnobotanical knowledge. Research will evaluate the effect of several social and cultural factors on the evolution of ethnobotanical knowledge of four compact, but divided ethnic minorities that had experienced for shorter (25 years) or longer (70 years) period different influences affecting their plant use and very different social conditions (including welfare and economy). As a long-term outcome, based on the result of present and consequent studies scientists will be able to predict the extent and depth of the changes occurring in the ethnobotanical knowledge and as a applied outcome learn to direct and educate people in the way that the knowledge necessary for sustainable maintenance and utilization of local plant resources will be constantly evolving in the way supporting health and well-being of different populations.", "To": ["2022-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2017-06-01"], "Project_ID": ["714874"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["ILMATIETEEN LAITOS", "HELSINGIN YLIOPISTO", "CONSIGLIO NAZIONALE DELLE RICERCHE", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "NATIONAL INSTITUTE OF RESEARCH AND DEVELOPMENT FOR OPTOELECTRONICS", "CESKY HYDROMETEOROLOGICKY USTAV", "LEIBNIZ INSTITUT FUER TROPOSPHAERENFORSCHUNG e.V.", "KARLSRUHER INSTITUT FUER TECHNOLOGIE", "NATIONAL OBSERVATORY OF ATHENS", "NORSK INSTITUTT FOR LUFTFORSKNING STIFTELSE", "UNIVERSITAT POLITECNICA DE CATALUNYA", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "UNIVERSIDAD DE VALLADOLID", "THE UNIVERSITY OF MANCHESTER", "NATURAL ENVIRONMENT RESEARCH COUNCIL", "SCIENCE AND TECHNOLOGY FACILITIES COUNCIL", "KONINKLIJK NEDERLANDS METEOROLOGISCH INSTITUUT-KNMI", "PAUL SCHERRER INSTITUT", "EIDGENOSSISCHE MATERIALPRUFUNGS- UND FORSCHUNGSANSTALT", "THE CYPRUS INSTITUTE", "Instytut Geofizyki Polskiej Akademii Nauk", "LUNDS UNIVERSITET", "INSTITUT ROYAL D'AERONOMIE SPATIALEDE BELGIQUE", "NATIONAL UNIVERSITY OF IRELAND GALWAY", "EESTI MAAULIKOOL", "AARHUS UNIVERSITET", "INSTITUTE OF NUCLEAR RESEARCH AND NUCLEAR ENERGY - BULGARIAN ACADEMY OF SCIENCES", "JRC -JOINT RESEARCH CENTRE- EUROPEAN COMMISSION"], "EU_Contribution": ["EUR 3 999 996,25"], "Project_Title": ["ACTRIS PPP - Aerosols, Clouds and Trace gases Preparatory Phase Project"], "Total_Cost": ["EUR 3 999 996,25"], "Country": ["Finland", "Finland", "Italy", "France", "Romania", "Czech Republic", "Germany", "Germany", "Greece", "Norway", "Spain", "Spain", "Spain", "United Kingdom", "United Kingdom", "United Kingdom", "Netherlands", "Switzerland", "Switzerland", "Cyprus", "Poland", "Sweden", "Belgium", "Ireland", "Estonia", "Denmark", "Bulgaria", "Belgium"], "Project_ACR": ["ACTRIS PPP"], "Technology_Description": "The Research Infrastructure (RI) ACTRIS \u2013 Aerosols, Clouds and Trace Gases - is the pan-European RI that consolidates activities amongst European partners for observations of aerosols, clouds, and trace gases and for understanding of the related atmospheric processes, to provide RI services to wide user groups. ", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["INFRADEV-02-2016 - Preparatory Phase and support to early phase of ESFRI projects"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Finland"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Other", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["739530"], "Call_for_Proposal": ["H2020-INFRADEV-2016-2"]}, -{"Partners": ["ISTITUTO NAZIONALE DI ASTROFISICA", "ISTITUTO NAZIONALE DI ASTROFISICA", "UNIVERSITAET HAMBURG", "ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA"], "EU_Contribution": ["EUR 1 496 250"], "Project_Title": ["Deciphering RAdio NOn-thermal Emission on the Largest scales"], "Total_Cost": ["EUR 1 496 250"], "Country": ["Italy", "Italy", "Germany", "Italy"], "Project_ACR": ["DRANOEL"], "Technology_Description": "This proposal aims to understand the origin of the radio emission detected in the most massive objects in our Universe: galaxy clusters.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["714245"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["LUNDS UNIVERSITET", "THE UNIVERSITY OF SHEFFIELD", "KOBENHAVNS UNIVERSITET", "OULUN YLIOPISTO", "AARHUS UNIVERSITET", "CLU srl", "ALFRED-WEGENER-INSTITUT HELMHOLTZ-ZENTRUM FUR POLAR- UND MEERESFORSCHUNG", "NORSK POLARINSTITUTT", "NATURAL ENVIRONMENT RESEARCH COUNCIL", "State Educational Institution of Higher Professional Education TOMSK STATE UNIVERSITY", "JIHOCESKA UNIVERZITA V CESKYCH BUDEJOVICICH", "POLARFORSKNINGSSEKRETARIETET", "NIBIO - NORSK INSTITUTT FOR BIOOKONOMI", "STOCKHOLMS UNIVERSITET", "HELSINGIN YLIOPISTO", "GRONLANDS NATURINSTITUT", "Instytut Geofizyki Polskiej Akademii Nauk", "TURUN YLIOPISTO", "UNIVERSITETET I OSLO", "LUONNONVARAKESKUS", "INSITUTE FOR BIOLOGICAL PROBLEMS OF CRYOLITHOZONE SIBERIAN BRANCH RUSSIAN ACADEMY OF SCIENCES", "M.V. LOMONOSOV MOSCOW STATE UNIVERSITY", "SVERIGES LANTBRUKSUNIVERSITET", "ZENTRALANSTALT FUR METEOROLOGIE UNDGEODYNAMIK", "UNIVERSITAET INNSBRUCK", "YUGRA STATE UNIVERSITY", "JARDFEINGI", "RANNSOKNARSTODIN RIF", "UNIVERSITE LAVAL", "INSTYTUT GEOGRAFII I PRZESTRZENNEGO ZAGOSPODAROWANIA IM STANISLAWA LESZCZYCKIEGO POLSKIEJ AKADEMII NAUK", "CONSIGLIO NAZIONALE DELLE RICERCHE", "University of Alaska", "SUDURNES SCIENCE AND LEARNING CENTER", "ILMATIETEEN LAITOS", "CAFF SKRIFSTOFAN A ISLANDI", "UNIVERSITETET I TROMSOE", "AURORA COLLEGE", "THE ARTIC INSTITUTE OF NORTH AMERICA", "UMBILICAL DESIGN AB", "AF TECHNOLOGY AB", "METEOROLOGISK INSTITUTT", "LANDBUNADARHASKOLI ISLANDS", "RIJKSUNIVERSITEIT GRONINGEN", "INTERNATIONAL POLAR FOUNDATION", "MAPILLARY AB", "University Centre in Svalbard"], "EU_Contribution": ["EUR 10 000 000"], "Project_Title": ["International Network for Terrestrial Research and Monitoring in the Arctic"], "Total_Cost": ["EUR 10 000 000"], "Country": ["Sweden", "United Kingdom", "Denmark", "Finland", "Denmark", "Italy", "Germany", "Norway", "United Kingdom", "Russia", "Czech Republic", "Sweden", "Norway", "Sweden", "Finland", "Greenland", "Poland", "Finland", "Norway", "Finland", "Russia", "Russia", "Sweden", "Austria", "Austria", "Russia", "Faeroe Islands", "Iceland", "Canada", "Poland", "Italy", "United States", "Iceland", "Finland", "Iceland", "Norway", "Canada", "Canada", "Sweden", "Sweden", "Norway", "Iceland", "Netherlands", "Belgium", "Sweden", "Norway"], "Project_ACR": ["INTERACT"], "Technology_Description": "INTERACT aims for a geographically comprehensive and excellent state-of-the-art terrestrial research infrastructure throughout the Arctic and adjoining forest and alpine regions to identify environmental change, to facilitate understanding and prediction of future change and to inform decision makers about societally-relevant impacts. INTERACT is the fundamental building block and one-stop-shop for EU and international projects, programmes and organisations requiring access to northern lands, data and services, and includes a rapid response capability to potential hazards. INTERACT is pan-Arctic, multidisciplinary and crosses EU call domains by linking to forest, coastal, marine and atmospheric communities. ", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["INFRAIA-01-2016-2017 - Integrating Activities for Advanced Communities"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Other", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Other", "Research Organisations", "Other", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["730938"], "Call_for_Proposal": ["H2020-INFRAIA-2016-1"]}, -{"Partners": ["THE UNIVERSITY OF SUSSEX", "THE UNIVERSITY OF SUSSEX"], "EU_Contribution": ["EUR 149 903"], "Project_Title": ["Design of a new non-existing layer of information delivery through smell"], "Total_Cost": ["EUR 149 903"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["OWidgets"], "Technology_Description": "The idea for this proposal is to demonstrate the design of olfactory widgets (OWidgets) as a proof-of-concept implementation based on the semantic integration of smell to convey specific information to the user. We will showcase the meaningful design of OWidgets in two distinct markets. Widgets are well established as simple application extensions, integrated in a larger application and usually pre-installed on a device. Widgets allow quick access to information without requiring a user to open the application that manages this information. OWidgets will expand the existing range of widgets and provide users with a new non-existing layer of information delivery through smell, and consequently allow the creation of novel experiences in various application contexts.", "To": ["2018-01-31, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-02-01"], "Project_ID": ["737576"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["UNIVERSITE DE FRANCHE-COMTE", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON", "CONSORZIO INTERUNIVERSITARIO NAZIONALE PER LA SCIENZA E TECNOLOGIA DEI MATERIALI", "INSTITUT POLYTECHNIQUE DE GRENOBLE", "UNIVERSITAET ZU KOELN", "CEDRAT TECHNOLOGIES SA", "AIXTRON SE", "STMICROELECTRONICS SRL"], "EU_Contribution": ["EUR 3 382 787,16"], "Project_Title": ["Piezoelectric Energy Harvesters for Self-Powered Automotive Sensors: from Advanced Lead-Free Materials to Smart Systems"], "Total_Cost": ["EUR 3 382 787,16"], "Country": ["France", "United Kingdom", "France", "Italy", "France", "Germany", "France", "Germany", "Italy"], "Project_ACR": ["ENHANCE"], "Technology_Description": "\"The proposed Initial Training Network entitled \"\"Piezoelectric Energy Harvesters for Self-Powered Automotive Sensors: from Advanced Lead-Free Materials to Smart Systems (ENHANCE)\"\" will provide Early Stage Researchers (ESRs) with broad and intensive training within a multidisciplinary research and teaching environment. Key training topics will include development of energy harvesters compatible with MEMS technology and able to power wireless sensor. Applied to automobiles, such technology will allow for 50 kg of weight saving, connection simplification, space reduction, and reduced maintenance costs - all major steps towards creating green vehicles. Other important topics include technology innovation, education and intellectual asset management.", "To": ["2021-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-05-01"], "Project_ID": ["722496"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["RELAIS CULTURE EUROPE ASSOCIATION", "UNIVERSITAT DE VALENCIA", "UDRUZENJE ZA KULTURU I UMJETNOST CRVENA", "BUNKER ZAVOD ZA ORGANIZACIJO IN IZVEDBO, KULTURNIH PRIREDITEV", "ZNANSTVENORAZISKOVALNI CENTER SLOVENSKE AKADEMIJE ZNANOSTI IN UMETNOSTI", "INSTITUT ZA KRIMINOLOGIJO PRI PRAVNI FAKULTETI V LJUBLJANI", "BEDEN ISLEMSEL SANATLAR DERNEGI", "IZMIR EKONOMI UNIVERSITESI", "ISTANBUL TEKNIK UNIVERSITESI", "FUNDACJA TEREN OTWARTY", "UNIVERSITY COLLEGE LONDON", "UNIVERSITA DEGLI STUDI DI PERUGIA", "ASSOCIAZIONE CITTA EUROPEA DEI MESTIERI D'ARTE", "GENERIQUES ASSOCIATION", "FORUM TUNISIEN POUR LES DROITS ECONOMIQUES ET SOCIAUX"], "EU_Contribution": ["EUR 1 858 500"], "Project_Title": ["Art / culture / economy to democratize society. Research in placemaking for alternative narratives"], "Total_Cost": ["EUR 1 858 500"], "Country": ["France", "Spain", "Bosnia and Herzegovina", "Slovenia", "Slovenia", "Slovenia", "Turkey", "Turkey", "Turkey", "Poland", "United Kingdom", "Italy", "Italy", "France", "Tunisia"], "Project_ACR": ["trans-making"], "Technology_Description": "The project trans-making aims to establish a multilateral network of research and innovation staff active in the fields of placemaking/place-based art activities as a space to create alternative narratives for social, economic and democratic renewal.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["France"], "Activity": ["Other", "Higher or Secondary Education Establishments", "Other", "Other", "Higher or Secondary Education Establishments", "Research Organisations", "Other", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other", "Other", "Other"], "From": ["2017-01-01"], "Project_ID": ["734855"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK", "THE EUROPEAN MARINE ENERGY CENTRE LIMITED", "INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER", "UNIVERSITY OF STRATHCLYDE", "FUNDACION TECNALIA RESEARCH & INNOVATION", "DANMARKS TEKNISKE UNIVERSITET", "WAVEC/OFFSHORE RENEWABLES - CENTRO DE ENERGIA OFFSHORE ASSOCIACAO", "AALBORG UNIVERSITET", "OFFSHORE RENEWABLE ENERGY CATAPULT", "FUNDACION INSTITUTO DE HIDRAULICA AMBIENTAL DE CANTABRIA", "STICHTING TIDAL TESTING CENTRE", "ECOLE CENTRALE DE NANTES", "FUNDACAO EUROCEAN", "SMARTBAY IRELAND", "SINTEF ENERGI AS", "THE UNIVERSITY OF EXETER", "FUNDACION CENER-CIEMAT", "CONSIGLIO NAZIONALE DELLE RICERCHE", "FLOWAVE TT LIMITED", "GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER", "STICHTING MARITIEM RESEARCH INSTITUUT NEDERLAND", "FUNDACION CENTRO TECNOLOGICO DE COMPONENTES", "UNIVERSITA DEGLI STUDI DI FIRENZE", "UNIVERSITY OF PLYMOUTH", "CONSORCIO PARA EL DISENO, CONSTRUCCION, EQUIPAMIENTO Y EXPLOTACION DE LA PLATAFORMA OCEANICA DE CANARIAS", "NATIONAL UNIVERSITY OF IRELAND GALWAY", "ENTE VASCO DE LA ENERGIA", "THE QUEEN'S UNIVERSITY OF BELFAST", "NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU", "UNIVERSITY OF SURREY", "SSPA SWEDEN AB.", "BISCAY MARINE ENERGY PLATFORM SA", "MARIENE INFORMATIE SERVICE MARIS BV", "CSC-TIETEEN TIETOTEKNIIKAN KESKUS OY", "UPPSALA UNIVERSITET", "OCEANIDE", "UNIVERSITY OF LIMERICK", "THE UNIVERSITY OF EDINBURGH", "EUROPEAN OCEANENERGY ASSOCIATION EU OEA"], "EU_Contribution": ["EUR 10 592 285,23"], "Project_Title": ["Marine Renewable Infrastructure Network for Enhancing Technologies 2"], "Total_Cost": ["EUR 10 592 285,23"], "Country": ["Ireland", "United Kingdom", "France", "United Kingdom", "Spain", "Denmark", "Portugal", "Denmark", "United Kingdom", "Spain", "Netherlands", "France", "Portugal", "Ireland", "Norway", "United Kingdom", "Spain", "Italy", "United Kingdom", "Germany", "Netherlands", "Spain", "Italy", "United Kingdom", "Spain", "Ireland", "Spain", "United Kingdom", "Norway", "United Kingdom", "Sweden", "Spain", "Netherlands", "Finland", "Sweden", "France", "Ireland", "United Kingdom", "Belgium"], "Project_ACR": ["MARINET2"], "Technology_Description": "Integrating activities planned under MaRINET 2 build upon the achievements of the advanced community created in MaRINET FP7. MaRINET 2 will ensure the continued integration and enhancement of all leading European research infrastructure and facilities specialising in research, development and testing of offshore renewable energy systems including electrical sub systems and grid integration through a range of TRLs (1-7). MaRINET FP7 proved the added value of uniting these facilities, and substantially improving their capability as a community of practice to deliver consistent testing services ensuring, quantifiable, stepwise innovation and progress in the development of devices and key components, and identifying critical areas for further technical investigation and enhancement. Whilst activities proposed under MaRINET 2 will follow the same formula, balancing networking/ joint research/ and transnational access, the consortium and scope of work is expanded to include xx partners in xx countries with xx facilities. The e-infrastructure programme fills a strategic gap. Taking stock of existing capacities for data management/sharing; it addresses user requirements and demonstrates the operation of a new system based on standards and tools adapted from the SeaDataNet infrastructure. The European Commission and member states recognise offshore renewable energy as an important source of clean energy that can: generate economic growth and employment; increase energy security; and boost competitiveness and technological innovation. The realisation of this potential depends on the accelerated development, deployment and grid integration of reliable, efficient technologies for harvesting offshore renewable energy, which in turn requires robust and exhaustive testing in dedicated facilities operated by practitioners with specialised expertise. MaRINET 2 provides this ecosystem, and is pre-eminently suited to fostering the next generation of offshore renewable energy devices.", "To": ["2021-06-30, ongoing project"], "Meta": [""], "Topic_s": ["INFRAIA-01-2016-2017 - Integrating Activities for Advanced Communities"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Other", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Other", "Other", "Higher or Secondary Education Establishments", "Other", "Other", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other"], "From": ["2017-01-01"], "Project_ID": ["731084"], "Call_for_Proposal": ["H2020-INFRAIA-2016-1"]}, -{"Partners": ["THE UNIVERSITY OF SHEFFIELD", "MAKEA INDUSTRIES GMBH", "HELSINGIN YLIOPISTO", "INSTITUTUL DE SOCIOLOGIE", "UNIVERSITETET I OSLO", "LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE", "AARHUS UNIVERSITET", "KOBENHAVNS UNIVERSITET", "HASKOLI ISLANDS", "HASKOLINN A AKUREYRI", "MAKERS PARTNERSHIP", "ASOCIATIA HATCH ATELIER", "RG MENNTARADGJOF SLF", "ARHUS KOMMUNE"], "EU_Contribution": ["EUR 531 000"], "Project_Title": ["MAKERSPACES IN THE EARLY YEARS: ENHANCING DIGITAL LITERACY AND CREATIVITY (MakEY)"], "Total_Cost": ["EUR 549 000"], "Country": ["United Kingdom", "Germany", "Finland", "Romania", "Norway", "United Kingdom", "Denmark", "Denmark", "Iceland", "Iceland", "United Kingdom", "Romania", "Iceland", "Denmark"], "Project_ACR": ["MakEY"], "Technology_Description": "This two-year project involves an international and inter-sector research and training network that focuses on the potential of makerspaces, which are specific spaces that enable creative design and the production of both digital and non-digital artefacts, to foster the digital literacy and creative skills of young children. A key aim of the project is to inform educational policy and practice in this area, enabling formal learning institutions (early years settings and primary schools) to learn from practice in non-formal learning spaces, and vice-versa, and also to foster innovation and entrepreneurship in the makerspace sector, enabling SMEs to develop robust business models and appropriate resources for future work in this area. The project involves 16 academic and non-academic beneficiaries and 10 non-academic, non-beneficiary partners across 6 EU countries (Denmark, Finland, Iceland, Norway, Romania, UK), an Associated Country (Colombia) and 4 Third Countries (Australia, Canada, South Africa and USA). This global network of university scholars, cultural industry partners in makerspaces, early years practitioners, museum educators and librarians will engage in a collaborative research and training programme that addresses 4 objectives, which are to:", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["734720"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "ISTITUTO NAZIONALE DI ASTROFISICA", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "SCIENCE AND TECHNOLOGY FACILITIES COUNCIL", "EUROPEAN SOUTHERN OBSERVATORY - ESO EUROPEAN ORGANISATION FOR ASTRONOMICAL RESEARCH IN THE SOUTHERN HEMISPHERE", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "UNIVERSITEIT LEIDEN", "FIRST LIGHT IMAGING SAS", "OFFICE NATIONAL D'ETUDES ET DE RECHERCHES AEROSPATIALES", "NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO", "INSTITUTO DE ASTROFISICA DE CANARIAS", "MAGYAR TUDOMANYOS AKADEMIA CSILLAGASZATI ES FOLDTUDOMANYI KUTATOKOZPONT", "UNIWERSYTET WARSZAWSKI", "NATIONAL OBSERVATORY OF ATHENS", "NATIONAL UNIVERSITY OF IRELAND GALWAY", "KOBENHAVNS UNIVERSITET", "UNIVERSITE DE LIEGE", "UNIVERSIDADE DO PORTO", "LEIBNIZ-INSTITUT FUR ASTROPHYSIK POTSDAM (AIP)", "POLITECNICO DI MILANO", "NORDIC OPTICAL TELESCOPE SCIENTIFIC ASSOCIATION", "DEPARTMENT OF INDUSTRY", "HERIOT-WATT UNIVERSITY", "THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS", "LIVERPOOL JOHN MOORES UNIVERSITY", "UNIVERSITY OF DURHAM", "THE UNIVERSITY OF EXETER", "UNIVERSITY OF BATH", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE UNIVERSITY OF SHEFFIELD", "INSTITUT D'OPTIQUE THEORIQUE ET APPLIQUEE IOTA - SUPOPTIQUE"], "EU_Contribution": ["EUR 10 000 000"], "Project_Title": ["Optical Infrared Coordination Network for Astronomy"], "Total_Cost": ["EUR 10 011 619,61"], "Country": ["United Kingdom", "France", "Italy", "Germany", "United Kingdom", "Germany", "Spain", "Netherlands", "France", "France", "Netherlands", "Spain", "Hungary", "Poland", "Greece", "Ireland", "Denmark", "Belgium", "Portugal", "Germany", "Italy", "Sweden", "Australia", "United Kingdom", "United Kingdom", "United Kingdom", "United Kingdom", "United Kingdom", "United Kingdom", "United Kingdom", "United Kingdom", "France"], "Project_ACR": ["OPTICON"], "Technology_Description": "Europe has become a global leader in optical-near infrared astronomy through excellence in space and ground-based experimental and theoretical research. While the major infrastructures are delivered through major national and multi-national agencies (ESO, ESA) their continuing scientific competitiveness requires a strong community of scientists and technologists distributed across Europe\u2019s nations.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["INFRAIA-01-2016-2017 - Integrating Activities for Advanced Communities"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["730890"], "Call_for_Proposal": ["H2020-INFRAIA-2016-1"]}, -{"Partners": ["UNIVERSITAET ZU KOELN", "UNIVERSITAET ZU KOELN"], "EU_Contribution": ["EUR 1 489 916"], "Project_Title": ["Social integration and boundary making in adolescence"], "Total_Cost": ["EUR 1 489 916"], "Country": ["Germany", "Germany"], "Project_ACR": ["SOCIALBOND"], "Technology_Description": "The idea of boundary making has moved to the centre of influential agendas in immigration research. While many studies show the location and meaning of ethnic boundaries to vary across contexts, the conditions under which actors pursue different strategies of boundary making and produce different configurations of boundaries remain largely unknown. A major reason is the lack of a contextual unit of analysis that allows one to look at a large number of comparable social fields in which processes of boundary making unfold.", "To": ["2022-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-02-01"], "Project_ID": ["716461"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["UNIVERSITY OF ULSTER", "UNIVERSIDAD DE JAEN", "NATIONAL UNIVERSITY OF IRELAND GALWAY", "LULEA TEKNISKA UNIVERSITET", "HOGSKOLAN I HALMSTAD", "UNIVERSITA DEGLI STUDI DI FIRENZE", "I+ SRL", "KARDE AS", "FUNDACION AGEING SOCIAL LAB", "ACADEMISCH ZIEKENHUIS GRONINGEN", "ASSOCIAZIONE NOVILUNIO", "SWEDISH ADRENALINE AB"], "EU_Contribution": ["EUR 976 500"], "Project_Title": ["The use of computational techniques to Improve compliance to reminders within smartenvironments"], "Total_Cost": ["EUR 1 084 500"], "Country": ["United Kingdom", "Spain", "Ireland", "Sweden", "Sweden", "Italy", "Italy", "Norway", "Spain", "Netherlands", "Italy", "Sweden"], "Project_ACR": ["REMIND"], "Technology_Description": "The aim of this Project is to create an International and Intersectoral network to facilitate the exchange of staff to progress developments in reminding technologies for persons with dementia which can be deployed in smart environments. The focus will be on developing staff and partner skills in the areas of user centered design and behavioral science coupled with improved computational techniques which in turn will offer more appropriate and efficacious reminding solutions. This will be further supported through research involving user centric studies into the use of reminding technologies and the theory of behaviour change to improve compliance of usage.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Higher or Secondary Education Establishments", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["734355"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSITE D'AVIGNON ET DES PAYS DE VAUCLUSE", "UNIVERSIDAD COMPLUTENSE DE MADRID", "CONSIGLIO NAZIONALE DELLE RICERCHE", "ADSI-AUSTRIAN DRUG SCREENING INSTITUTE GMBH", "PHARMAGNOSE VIOTECHNOLOGIKI ANONYMI ETAIREIA", "UNI-PHARMA KLEON TSETIS, FARMAKEFTIKA ERGASTIRIA ANONYMOS VIOMICHANIKIKAI EMPORIKI", "SERVIZO GALEGO DE SAUDE", "NATAC BIOTECH SL", "ALNUMED GMBH", "NEURO-SYS"], "EU_Contribution": ["EUR 1 732 500"], "Project_Title": ["Bioactive compounds from Olea europaea: investigation and application in food, cosmetic and pharmaceutical industry"], "Total_Cost": ["EUR 1 732 500"], "Country": ["Greece", "France", "France", "Spain", "Italy", "Austria", "Greece", "Greece", "Spain", "Spain", "Germany", "France"], "Project_ACR": ["Olive-Net"], "Technology_Description": "The goal of Olive-Net project is to introduce a novel approach for the exploration, valorization and marketing of new products based on bioactive compounds from Olea europaea. This will be achieved through an extended and well-balanced scheme of researcher\u2019s secondments between universities and enterprises from EU & Associated countries as well as universities from Third countries. A mutual scientific project developed on the needs and interests of both sectors exploiting the existing expertise will be the base of this proposal. Products and side-products of the olive tree such as olive oil, edible olive fruits, olive mill waste and olive tree leaves, will be subjected to a series of state-of-the-art extraction and isolation cascades in order to provide extracts, enriched fractions and isolated compounds of high purity. Target chemical categories will involve the well known olive oil polyphenols and secoiridoids, that will be assessed for their safety and pharmacological effects against inflammation, osteoarthritis, cardiovascular disease, etc. in cell-based and in vivo assays. All active ingredients will be identified and characterized with advanced analytical techniques, in order to be integrated in formulations and products in the area of nutraceuticals/dietary supplements. Within this project, core scientific multidisciplinary knowledge from different research areas will be integrated creating valuable synergies. Expertise will be transferred by means of the seconded researchers training in environments with different research orientation where complimentary skills are required. Special attention will be given to dissemination activities aiming to public awareness of benefits of healthy diet(s). Olive-Net aspires to create a successful model promoting considerably researchers\u2019 competences and long-lasting collaboration between Industry and Academia.", "To": ["2021-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Greece"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-03-01"], "Project_ID": ["734899"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH", "EUROPEAN SPALLATION SOURCE ERIC", "RHP TECHNOLOGY GMBH", "ION BEAM APPLICATIONS SA", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "Soci\u00e9t\u00e9 civile SYNCHROTRON SOLEIL", "Bruker HTS GmbH", "STIFTUNG DEUTSCHES ELEKTRONEN-SYNCHROTRON DESY", "FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.", "GSI HELMHOLTZZENTRUM FUER SCHWERIONENFORSCHUNG Gmbh", "HEIDELBERGER IONENSTRAHL THERAPIE (HIT) BETRIEBS GESELLSCHAFT AM UNIVERSITATSKLINIKUM HEIDELBERG MIT BESCHRANKTER HAFTUNG", "HELMHOLTZ-ZENTRUM BERLIN FUR MATERIALIEN UND ENERGIE GMBH", "JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN", "JOHANNES GUTENBERG-UNIVERSITAT MAINZ", "KARLSRUHER INSTITUT FUER TECHNOLOGIE", "UNIVERSITAET SIEGEN", "MAGYAR TUDOMANYOS AKADEMIA WIGNER FIZIKAI KUTATOKOZPONT", "CONSIGLIO NAZIONALE INGEGNERI", "ISTITUTO NAZIONALE DI FISICA NUCLEARE", "POLITECNICO DI MILANO", "POLITECNICO DI TORINO", "RIGAS TEHNISKA UNIVERSITATE", "UNIVERSITA TA MALTA", "UNIVERSITEIT TWENTE", "INSTYTUT CHEMII I TECHNIKI JADROWEJ", "POLITECHNIKA WARSZAWSKA", "ASSOCIACAO DO INSTITUTO SUPERIOR TECNICO PARA A INVESTIGACAO E DESENVOLVIMENTO", "\"INSTITUTUL NATIONAL DE CERCETARE -DEZVOLTARE PENTRU FIZICA SI INGINERIE NUCLEARA \"\"HORIA HULUBEI\"\" (IFIN-HH)\"", "Institute of Electrical Engineering, Slovak Academy of Sciences", "COSYLAB LABORATORIJ ZA KONTROLNE SISTEME DD", "CONSORCIO PARA LA CONSTRUCCION EQUIPAMIENTO Y EXPLOTACION DEL LABORATORIO DE LUZ SINCROTRON", "CENTRO DE INVESTIGACIONES ENERGETICAS, MEDIOAMBIENTALES Y TECNOLOGICAS-CIEMAT", "LUNDS UNIVERSITET", "UPPSALA UNIVERSITET", "PAUL SCHERRER INSTITUT", "UNIVERSITE DE GENEVE", "THE UNIVERSITY OF HUDDERSFIELD", "SCIENCE AND TECHNOLOGY FACILITIES COUNCIL", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 10 000 000"], "Project_Title": ["Accelerator Research and Innovation for European Science and Society"], "Total_Cost": ["EUR 10 176 755,75"], "Country": ["Switzerland", "Sweden", "Austria", "Belgium", "France", "France", "France", "Germany", "Germany", "Germany", "Germany", "Germany", "Germany", "Germany", "Germany", "Germany", "Germany", "Germany", "Hungary", "Italy", "Italy", "Italy", "Italy", "Latvia", "Malta", "Netherlands", "Poland", "Poland", "Portugal", "Romania", "Slovakia", "Slovenia", "Spain", "Spain", "Sweden", "Sweden", "Switzerland", "Switzerland", "United Kingdom", "United Kingdom", "United Kingdom"], "Project_ACR": ["ARIES"], "Technology_Description": "Particle accelerators are essential tools for delivering excellence in many scientific fields and are widely used in industrial, healthcare and other applications. The demand of pushing further their scientific reach and of reinforcing their impact on society results in new challenges that must be addressed in the years to come: existing infrastructures are stretched to all performance frontiers, several world-class accelerator-based facilities on the ESFRI roadmap are under construction, and strategic decisions are needed for future accelerator facilities, to be realised on a global scale. ", "To": ["2021-04-30, ongoing project"], "Meta": [""], "Topic_s": ["INFRAIA-01-2016-2017 - Integrating Activities for Advanced Communities"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Switzerland"], "Activity": ["Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Denise Ogden", "Tel.: +44-1484-473192", "Fax: +44-1484-472682", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["730871"], "Call_for_Proposal": ["H2020-INFRAIA-2016-1"]}, -{"Partners": ["UNIVERSITETET I OSLO", "UNIVERSITETET I OSLO"], "EU_Contribution": ["EUR 1 476 948"], "Project_Title": ["The Global and Local Organization of Production"], "Total_Cost": ["EUR 1 476 948"], "Country": ["Norway", "Norway"], "Project_ACR": ["GLOBALPROD"], "Technology_Description": "A defining feature of the global economy is the gradual fragmentation of production across firms and", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["715147"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "STICHTING ASTRON, NETHERLANDS INSTITUTE FOR RADIO ASTRONOMY", "INSTITUT DE RADIO ASTRONOMIE MILLIMETRIQUE SOCIETE CIVILE", "ISTITUTO NAZIONALE DI ASTROFISICA", "JOINT INSTITUTE FOR VERY LONG BASELINE INTERFEROMETRY AS A EUROPEAN RESEARCH INFRASTRUCTURE CONSORTIUM (JIV-ERIC)", "THE UNIVERSITY OF MANCHESTER", "CHALMERS TEKNISKA HOEGSKOLA AB", "SCIENCE AND TECHNOLOGY FACILITIES COUNCIL", "STICHTING SRON NETHERLANDS INSTITUTE FOR SPACE RESEARCH", "OBSERVATOIRE DE PARIS", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "UNIVERSIDAD DE ALCALA", "EUROPEAN SOUTHERN OBSERVATORY - ESO EUROPEAN ORGANISATION FOR ASTRONOMICAL RESEARCH IN THE SOUTHERN HEMISPHERE", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.", "RIJKSUNIVERSITEIT GRONINGEN", "DUBLIN INSTITUTE FOR ADVANCED STUDIES", "STICHTING INTERNATIONAL LOFAR TELESCOPE", "UNIWERSYTET MIKOLAJA KOPERNIKA W TORUNIU", "UNIVERSITAET ZU KOELN", "VENTSPILS AUGSTSKOLA", "AALTO-KORKEAKOULUSAATIO", "THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN", "KOREA ASTRONOMY AND SPACE SCIENCE INSTITUTE", "TURUN YLIOPISTO", "UNIVERSITE DE BORDEAUX", "TECHNISCHE UNIVERSITEIT DELFT", "UNIVERSITY OF GLASGOW", "DEPARTMENT OF SCIENCE AND TECHNOLOGY"], "EU_Contribution": ["EUR 10 000 000"], "Project_Title": ["Advanced Radio Astronomy in Europe"], "Total_Cost": ["EUR 10 513 023,13"], "Country": ["Germany", "Netherlands", "France", "Italy", "Netherlands", "United Kingdom", "Sweden", "United Kingdom", "Netherlands", "France", "United Kingdom", "Spain", "Germany", "Germany", "Netherlands", "Ireland", "Netherlands", "Poland", "Germany", "Latvia", "Finland", "Ireland", "South Korea", "Finland", "France", "Netherlands", "United Kingdom", "South Africa"], "Project_ACR": ["RadioNet"], "Technology_Description": "RadioNet is a consortium of 28 institutions in Europe, Republic of Korea and South Africa, integrating at European level world-class infrastructures for research in radio astronomy. These include radio telescopes, telescope arrays, data archives and the globally operating European Network for Very Long Baseline Interferometry (EVN). RadioNet is de facto widely regarded to represent the interests of radio astronomy in Europe.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["INFRAIA-01-2016-2017 - Integrating Activities for Advanced Communities"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["730562"], "Call_for_Proposal": ["H2020-INFRAIA-2016-1"]}, -{"Partners": ["UNIVERSITAET ZU KOELN", "UNIVERSITAET ZU KOELN"], "EU_Contribution": ["EUR 1 495 875"], "Project_Title": ["An Exascale aware and Un-crashable Space-Time-Adaptive Discontinuous Spectral Element Solver for Non-Linear Conservation Laws"], "Total_Cost": ["EUR 1 495 875"], "Country": ["Germany", "Germany"], "Project_ACR": ["Extreme"], "Technology_Description": "\"The dynamics of fluids and plasma is described by non-linear conservation laws. Transient behaviour on multiple scales involving turbulence and shocks is intrinsic to these problems. Due to their low dispersion and dissipation errors, adaptive high order numerical methods currently receive growing attention in academia and industry and form an emerging key technology. The potential benefits are massively improved computational efficiency and drastic reduction in memory consumption. Both benefits can be easily justified theoretically, in particular for a space-time adaptive high order method. However, due to high algorithmic complexity, the theoretical performance is difficult to sustain on massively parallel supercomputers. The first challenge that we will address in this project is to design novel, exascale aware, space-time adaptive algorithms and implement them in an open source solver that will scale on over 10^6 computing cores. Another indispensable property for the successful industrialisation of space-time adaptive high order methods is robustness. Robustness, i.e. an \"\"un-crashable\"\" solver, which still retains all the positive benefits of the high order scheme is the \"\"holy grail\"\" of the current research on these methods. This requires new mathematical concepts. The second challenge we will address here is to construct a provable un-crashable, space-time adaptive, high order solver without excessive artificial dissipation. Our mathematical key to achieve robustness is not intuitive at first sight: skew-symmetry. We will show that a specific skew-symmetric formulation guided by careful mathematics will allow us to design methods that are consistent with the second law of thermodynamics. This physical consistency is important as it will enable us to construct a new class of un-crashable space-time adaptive high order methods. We will demonstrate the supremacy of this efficient and robust solver in complex large scale science and engineering applications.\"", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["714487"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER", "MARIENE INFORMATIE SERVICE MARIS BV", "NATURAL ENVIRONMENT RESEARCH COUNCIL", "BUNDESAMT FUR SEESCHIFFFAHRT UND HYDROGRAPHIE", "SVERIGES METEOROLOGISKA OCH HYDROLOGISKA INSTITUT", "INSTITUTO ESPANOL DE OCEANOGRAFIA", "HELLENIC CENTRE FOR MARINE RESEARCH", "ISTITUTO NAZIONALE DI OCEANOGRAFIA E DI GEOFISICA SPERIMENTALE", "ALL-RUSSIAN RESEARCH INSTITUTE OF HYDROMETEOROLOGICAL INFORMATION-WORLD DATA CENTRE", "AGENZIA NAZIONALE PER LE NUOVE TECNOLOGIE, L'ENERGIA E LO SVILUPPO ECONOMICO SOSTENIBILE", "ISTITUTO NAZIONALE DI GEOFISICA E VULCANOLOGIA", "MIDDLE EAST TECHNICAL UNIVERSITY", "ALFRED-WEGENER-INSTITUT HELMHOLTZ-ZENTRUM FUR POLAR- UND MEERESFORSCHUNG", "UNIVERSITE DE LIEGE", "HAVFORSKNINGSINSTITUTTET", "AARHUS UNIVERSITET", "International Council for the Exploration of the Sea", "JRC -JOINT RESEARCH CENTRE- EUROPEAN COMMISSION", "MARINE INSTITUTE", "INSTITUTO HIDROGRAFICO", "STICHTING NIOZ, KONINKLIJK NEDERLANDS INSTITUUT VOOR ONDERZOEK DER ZEE", "INSTITUT ROYAL DES SCIENCES NATURELLES DE BELGIQUE", "VLAAMS INSTITUUT VOOR DE ZEE VZW", "HAFRANNSOKNASTOFNUNIN", "ILMATIETEEN LAITOS", "INSTYTUT METEOROLOGII I GOSPODARKIWODNEJ - PANSTWOWY INSTYTUT BADAWCZY", "TALLINNA TEHNIKAULIKOOL", "LATVIJAS HIDROEKOLOGIJAS INSTITUTS", "P.P. SHIRSHOV INSTITUTE OF OCEANOLOGY OF RUSSIAN ACADEMY OF SCIENCES", "INSTITUTE OF OCEANOLOGY - BULGARIAN ACADEMY OF SCIENCES", "INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE MARINA GRIGORE ANTIPA", "IVANE JAVAKHISHVILI TBILISI STATE UNIVERSITY", "Institute of Oceanography and Fisheries", "NACIONALNI INSTITUT ZA BIOLOGIJO", "UNIVERSITA TA MALTA", "ISRAEL OCEANOGRAPHIC AND LIMNOLOGICAL RESEARCH LIMITED", "CONSIGLIO NAZIONALE DELLE RICERCHE", "INSTYTUT OCEANOLOGII POLSKIEJ AKADEMII NAUK", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "STICHTING DELTARES", "SUOMEN YMPARISTOKESKUS", "UKRAINIAN SCIENTIFIC CENTRE OF ECOLOGY OF THE SEA", "ETT SPA", "EUROGOOS", "DEUTSCHES KLIMARECHENZENTRUM GMBH", "CINECA CONSORZIO INTERUNIVERSITARIO", "CSC-TIETEEN TIETOTEKNIIKAN KESKUS OY", "SCIENCE AND TECHNOLOGY FACILITIES COUNCIL", "ETHNIKO DIKTYO EREVNAS TECHNOLOGIAS AE", "UNIVERSITETET I BERGEN", "HELMHOLTZ ZENTRUM FUR OZEANFORSCHUNG KIEL", "52\u00b0North Initiative for Geospatial Open Source Software GmbH", "SERVICE HYDROGRAPHIQUE ET OCEANOGRAPHIQUE DE LA MARINE", "ORION - INSTITOUTO AEIFORIAS KAI ANAPTIKSEON", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA"], "EU_Contribution": ["EUR 9 999 737,50"], "Project_Title": ["SeaDataCloud - Further developing the pan-European infrastructure for marine and ocean data management"], "Total_Cost": ["EUR 9 999 737,50"], "Country": ["France", "Netherlands", "United Kingdom", "Germany", "Sweden", "Spain", "Greece", "Italy", "Russia", "Italy", "Italy", "Turkey", "Germany", "Belgium", "Norway", "Denmark", "Denmark", "Belgium", "Ireland", "Portugal", "Netherlands", "Belgium", "Belgium", "Iceland", "Finland", "Poland", "Estonia", "Latvia", "Russia", "Bulgaria", "Romania", "Georgia", "Croatia", "Slovenia", "Malta", "Israel", "Italy", "Poland", "Spain", "Netherlands", "Finland", "Ukraine", "Italy", "Belgium", "Germany", "Italy", "Finland", "United Kingdom", "Greece", "Norway", "Germany", "Germany", "France", "Cyprus", "France", "Italy"], "Project_ACR": ["SeaDataCloud"], "Technology_Description": "The SeaDataNet pan-European infrastructure has been developed by NODCs and major research institutes from 34 countries. Over 100 marine data centres are connected and provide discovery and access to data resources for all European researchers. Moreover, SeaDataNet is a key infrastructure driving several portals of the European Marine Observation and Data network (EMODnet), initiated by EU DG-MARE for Marine Knowledge, MSFD, and Blue Growth. SeaDataNet complements the Copernicus Marine Environmental Monitoring Service (CMEMS), coordinated by EU DG-GROW. However, more effective and convenient access is needed to better support European researchers. The standards, tools and services developed must be reviewed and upgraded to keep pace with demand, such as developments of new sensors, and international and IT standards. Also EMODnet and Copernicus pose extra challenges to boost performance and foster INSPIRE compliance. More data from more data providers must be made available, from European and international research projects and observing programmes. ", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["INFRAIA-01-2016-2017 - Integrating Activities for Advanced Communities"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Research Organisations", "Research Organisations", "Other", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Other", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2016-11-01"], "Project_ID": ["730960"], "Call_for_Proposal": ["H2020-INFRAIA-2016-1"]}, -{"Partners": ["SCHWEIZERISCHER NATIONALFONDS ZUR FORDERUNG DER WISSENSCHAFTLICHEN FORSCHUNG", "DEUTSCHES ZENTRUM FUER LUFT - UND RAUMFAHRT EV", "SOCIEDAD PARA EL FOMENTO DE LA INNOVACION TECNOLOGICA S.L. - INNOVATEC", "HERMANN VON HELMHOLTZ-GEMEINSCHAFT DEUTSCHER FORSCHUNGSZENTREN EV", "NEDERLANDSE ORGANISATIE VOOR WETENSCHAPPELIJK ONDERZOEK", "COMISSAO DE COORDENACAO E DESENVOLVIMENTO REGIONAL DO CENTRO", "USTAV FYZIKALNI CHEMIE J. HEYROVSKEHO AV CR, v. v. i.", "SERVICE PUBLIC FEDERAL DE PROGRAMMATION POLITIQUE SCIENTIFIQUE", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CONSIGLIO NAZIONALE DELLE RICERCHE", "SCIENCE FOUNDATION IRELAND SFI", "UNIVERSITE DE LAUSANNE", "WROCLAWSKIE CENTRUM BADAN EIT+ SPZOO"], "EU_Contribution": ["EUR 1 992 983,75"], "Project_Title": ["Towards better Synchronisation of Priority Settings and Evaluation Mechanisms for Research Infrastructures Beyond National Relevance"], "Total_Cost": ["EUR 2 001 983,75"], "Country": ["Switzerland", "Germany", "Spain", "Germany", "Netherlands", "Portugal", "Czech Republic", "Belgium", "France", "Italy", "Ireland", "Switzerland", "Poland"], "Project_ACR": ["InRoad"], "Technology_Description": "The main objective of the proposal is to contribute to a better harmonisation and synchronisation of priority-setting-, funding- evaluation and life-cycle management of Research Infrastructures (RI through the exchange of best practices among the main stakeholders in member states, associated countries and at European level. The regional dimension will explicitly be taken into account by integrating, where appropriate, smart specialisation strategies in the work carried out.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["INFRASUPP-01-2016 - Policy and international cooperation measures for research infrastructures"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Switzerland"], "Activity": ["Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2017-01-01"], "Project_ID": ["730928"], "Call_for_Proposal": ["H2020-INFRASUPP-2016-1"]}, -{"Partners": ["UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN", "UNIVERSIDAD DE VALLADOLID", "LINKOPINGS UNIVERSITET", "THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN", "LABORATORIO IBERICO INTERNACIONAL DE NANOTECNOLOGIA", "NATIONAL UNIVERSITY OF IRELAND GALWAY", "THE QUEEN'S UNIVERSITY OF BELFAST", "UNIVERSIDAD COMPLUTENSE DE MADRID", "KARLSRUHER INSTITUT FUER TECHNOLOGIE", "ZECLINICS SL", "LENTIMED MEDICAL DEVICES SL", "Experimental Pharmacology and Oncology Berlin-Buch GmbH", "XENOPAT SL", "ECM INGENIERIA AMBIENTAL SL", "ICON CLINICAL RESEARCH LIMITED", "OCUPHARM DIAGNOSTICS SL", "VORNIA LIMITED"], "EU_Contribution": ["EUR 945 000"], "Project_Title": ["Drug Discovery and Delivery NEtwork for ONcology and Eye Therapeutics"], "Total_Cost": ["EUR 945 000"], "Country": ["Ireland", "Spain", "Sweden", "Ireland", "Portugal", "Ireland", "United Kingdom", "Spain", "Germany", "Spain", "Spain", "Germany", "Spain", "Spain", "Ireland", "Spain", "Ireland"], "Project_ACR": ["3D NEONET"], "Technology_Description": "Severe ocular disorders are affecting the lives of more than 100Mill people world-wide and at least 25% of the population above 70 years of age, a growing demographic group in EU. More than 8 million people lose their lives to cancer every year, making cancer a leading cause of pre-mature mortality in the world. The main hallmarks of severe eye conditions (i.e angiogenesis, inflammation and vascular permeability) play also pivotal roles in cancer, being therapeutic targets to treat both kind of diseases.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["734907"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["ATOS SPAIN SA", "TECHNISCHE UNIVERSITAET BERLIN", "UNIVERSITE DE STRASBOURG", "STIFTELSEN SINTEF", "BCAM - BASQUE CENTER FOR APPLIED MATHEMATICS", "SZECHENYI ISTVAN UNIVERSITY", "Konrad-Zuse-Zentrum f\u00fcr Informationstechnik Berlin", "FUNDACION PUBLICA GALLEGA CENTRO TECNOLOGICO DE SUPERCOMPUTACION DE GALICIA", "KUNGLIGA TEKNISKA HOEGSKOLAN", "STICHTING EUROPEAN SERVICE NETWORK OF MATHEMATICS FOR INDUSTRY AND INNOVATION"], "EU_Contribution": ["EUR 2 435 064,50"], "Project_Title": ["Mathematical Modelling, Simulation and Optimization for Societal Challenges with Scientific Computing"], "Total_Cost": ["EUR 2 435 064,50"], "Country": ["Spain", "Germany", "France", "Norway", "Spain", "Hungary", "Germany", "Spain", "Sweden", "Netherlands"], "Project_ACR": ["MSO4SC"], "Technology_Description": "The challenges of society show rising complexity and their solution process increasingly requires a holistic approach. It is necessary to provide decision makers with tools that allow long-term risk analysis, improvements or even optimization and control. ", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["EINFRA-22-2016 - User-driven e-infrastructure innovation"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Spain"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Other"], "From": ["2016-10-01"], "Project_ID": ["731063"], "Call_for_Proposal": ["H2020-EINFRA-2016-1"]}, -{"Partners": ["MALMO HOGSKOLA", "UNIVERSITY OF STRATHCLYDE", "UMEA UNIVERSITET", "BUNDESANSTALT FUER MATERIALFORSCHUNG UND -PRUEFUNG", "SYDDANSK UNIVERSITET", "UNIVERSITETET I OSLO", "KOBENHAVNS UNIVERSITET", "LINNEUNIVERSITETET"], "EU_Contribution": ["EUR 2 982 879"], "Project_Title": ["Smart capture phases for proteomics, glycomics and biomarker assays"], "Total_Cost": ["EUR 2 982 879"], "Country": ["Sweden", "United Kingdom", "Sweden", "Germany", "Denmark", "Norway", "Denmark", "Sweden"], "Project_ACR": ["BioCapture"], "Technology_Description": "The overall objective of BioCapture is to develop novel robust assays for proteinaceous biomarkers associated with cancer and to develop innovative tools for assaying elusive cancer related posttranslational modifications in proteins. This will be achieved by exploiting robust glycan, peptide and protein binders in the form of Molecularly Imprinted Polymers (MIPs) or plastic antibodies alongside generic enrichment combined with selected reaction monitoring-based mass spectrometry assays. In addition, sequence specific MIPs for multiple proteotypic peptides will be developed for use as capture phases in array format followed by MS or fluorescence based readout as well as a coupling of both detection techniques. The artificial receptors will be developed by various Molecular Imprinting techniques. The research results will lead to technological advances having a major impact on 1) health care since it will profit from methods for earlier, more reliable diagnosis of diseases, 2) drug discovery allowing a faster target or biomarker identification; and 3) biochemistry research laboratories in resulting in improved protein fractionation tools for revealing low abundant post translational modifications. The training of researchers will be performed by a consortium consisting of in total 15 partners whereof 6 polymer/materials research groups, 5 protein/glycan chemistry/analysis groups, 1 separation technology companies, 2 expert groups on platforms for multiplex analysis and one diagnostic company. This forms the basis for a very exciting interdisciplinary training program. Thus 11 early stage researchers (ESRs) working on specific tasks within five work packages will follow a rich training program providing a well-balanced spectrum of scientific, business and entrepreneurial skills.", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-11-01"], "Project_ID": ["722171"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["DANMARKS TEKNISKE UNIVERSITET", "UNIVERSIDAD AUTONOMA DE MADRID", "LUNDS UNIVERSITET", "UNIVERSITETET I OSLO", "POLITECNICO DI MILANO", "UNIVERSITAT DE BARCELONA", "FELIXROBOTICS BV", "NOVAHEP AB", "BIOMODICS APS"], "EU_Contribution": ["EUR 4 028 783,40"], "Project_Title": ["European Training Network for Cell-based Regenerative Medicine"], "Total_Cost": ["EUR 4 028 783,40"], "Country": ["Denmark", "Spain", "Sweden", "Norway", "Italy", "Spain", "Netherlands", "Sweden", "Denmark"], "Project_ACR": ["Training4CRM"], "Technology_Description": "The main objective of Training4CRM is to train a new generation of 15 highly inter-disciplinary early stage researchers at the highest international level and quality, who will be immediately employable in both the academic and industrial sectors due to their highly sought after cross- and interdisciplinary insights and expertise. Training4CRM addresses existing gaps within Cell-based Regenerative Medicine for treatment of neurodegenerative disorders (e.g. Parkinson\u00b4s, Huntington\u00b4s, Epilepsy), which occur as a result of progressive loss of structure, function and/or death of neurons in the brain. The disorders have a high prevalence and are associated with impairments and disabilities with high emotional, financial and social burden. New scientific discoveries and technologies are needed, and Training4CRM sets out with the ambition to educate and train students within and across different scientific disciplines to be able to master the design, fabrication and testing of completely new tools and materials within the fields of: Micro- and Nanoengineering (nano/microstructures, 3D scaffolds and 3D lab-on-a-chip devices of different materials, geometries, architectures and properties, wireless electronic components; Biotechnology (human stem cells, human induced pluripotent stem cells, optogenetics, tissue engineering; Pre-clinical studies for the purpose of investigating in vivo, in experimental animals, how the developed cells, materials, structures affect the animal at the physiological and behavioral levels, unravelling the therapeutic effects of the developed strategies.", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-11-01"], "Project_ID": ["722779"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["NATIONAL UNIVERSITY OF IRELAND GALWAY", "INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE", "ENIOS APPLICATIONS IDIOTIKI KEFALAIOUCHIKI ETAIREIA", "METASYSX GMBH"], "EU_Contribution": ["EUR 832 500"], "Project_Title": ["Targeting IRE1 in disease"], "Total_Cost": ["EUR 886 500"], "Country": ["Ireland", "France", "Greece", "Germany"], "Project_ACR": ["INSPIRED"], "Technology_Description": "The overarching objective of this Interfere to Suppress or Promote IRE1 (INSPIRED) RISE programme is to drive research and innovation in cell stress and drug development for cancer and neurodegenerative diseases by forming an interdisciplinary and intersectoral network of experts with strong, dynamic and productive interactions. The partners will work together, each bringing their unique expertise, to develop new classes of therapeutics for these common diseases. By fostering a shared culture of research, innovation and collaboration, the participants will accelerate advances in the field of cell stress responses. The staff members who participate in the programme will develop new skills, learn new technologies and be exposed to new environments which will considerably enhance their career opportunities. Advancing drug development in the stress response field has potential translational and commercial opportunities for the participants and will benefit European society as a whole from economic and health perspectives.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["734749"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["FORSCHUNGSZENTRUM JULICH GMBH", "Gauss Centre for Supercomputing (GCS) e.V.", "GRAND EQUIPEMENT NATIONAL DE CALCUL INTENSIF", "THE UNIVERSITY OF EDINBURGH", "BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION", "CSC-TIETEEN TIETOTEKNIIKAN KESKUS OY", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "SURFSARA BV", "UPPSALA UNIVERSITET", "CINECA CONSORZIO INTERUNIVERSITARIO", "INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK", "UNINETT SIGMA2 AS", "ETHNIKO DIKTYO EREVNAS TECHNOLOGIAS AE", "UNIVERSIDADE DE COIMBRA", "NATIONAL UNIVERSITY OF IRELAND GALWAY", "ISTANBUL TEKNIK UNIVERSITESI", "THE CYPRUS INSTITUTE", "\"ASSOCIATION \"\"NATIONAL CENTRE FOR SUPERCOMPUTING APPLICATIONS\"", "VYSOKA SKOLA BANSKA - TECHNICKA UNIVERZITA OSTRAVA", "NEMZETI INFORMACIOS INFRASTRUKTURA FEJLESZTESI IRODA", "KORMANYZATI INFORMATIKAI FEJLESZTESI UGYNOKSEG", "KOBENHAVNS UNIVERSITET", "MACHBA - INTERUNIVERSITY COMPUTATION CENTER", "PARTNERSHIP FOR ADVANCED COMPUTINGIN EUROPE AISBL", "UNIVERZA V LJUBLJANI", "VYPOCTOVE STREDISKO SLOVENSKEJ AKADEMIE VIED", "CENTRE DE RECHERCHE EN AERONAUTIQUE ASBL - CENAERO"], "EU_Contribution": ["EUR 15 000 000"], "Project_Title": ["PRACE 5th Implementation Phase Project"], "Total_Cost": ["EUR 16 105 293,69"], "Country": ["Germany", "Germany", "France", "United Kingdom", "Spain", "Finland", "Switzerland", "Netherlands", "Sweden", "Italy", "Poland", "Norway", "Greece", "Portugal", "Ireland", "Turkey", "Cyprus", "Bulgaria", "Czech Republic", "Hungary", "Hungary", "Denmark", "Israel", "Belgium", "Slovenia", "Slovakia", "Belgium"], "Project_ACR": ["PRACE-5IP"], "Technology_Description": "PRACE, the Partnership for Advanced Computing is the permanent pan-European High Performance Computing service providing world-class systems for world-class science. Systems at the highest performance level (Tier-0) are deployed by Germany, France, Italy and Spain providing researchers with over 11 billion core hours of compute time. HPC experts from 25 member states enabled users from academia and industry to ascertain leadership and remain competitive in the Global Race. Currently PRACE is in transition to PRACE 2, the successor of the initial five year period. The objectives of PRACE-5IP are to build on and seamlessly continue the successes of PRACE and start new innovative and collaborative activities proposed by the consortium. These include: assisting the transition to PRACE 2 including an analysis of Trans National Access; strengthening the internationally recognised PRACE brand; continuing and extend advanced training which so far provided more than 18 800 persontraining days; preparing strategies and best practices towards Exascale computing; coordinating and enhancing the operation of the multi-tier HPC systems and services; and supporting users to exploit massively parallel systems and novel architectures. A high level Service Catalogue is provided. The proven project structure will be used to achieve each of the objectives in 6 dedicated work packages. The activities are designed to increase Europe's research and innovation potential especially through: seamless and efficient Tier-0 services and a pan-European HPC ecosystem including national capabilities; promoting take-up by industry and new communities and special offers to SMEs; implementing a new flexible business model for PRACE 2; proposing strategies for deployment of leadership systems; collaborating with the ETP4HPC, CoEs and other European and international organisations on future architectures, training, application support and policies. This will be monitored through a set of KPIs.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["EINFRA-11-2016 - Support to the next implementation phase of Pan-European High Performance Computing infrastructure and services (PRACE)"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations", "Other", "Higher or Secondary Education Establishments", "Research Organisations", "Other", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Other", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations"], "From": ["2017-01-01"], "Project_ID": ["730913"], "Call_for_Proposal": ["H2020-EINFRA-2016-1"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM", "FEMTONICS KUTATO ES FEJLESZTO KORLATOLT FELELOSSEGU TARSASAG", "MAGYAR TUDOMANYOS AKADEMIA WIGNER FIZIKAI KUTATOKOZPONT", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "ACQUIFER AG", "UNIVERSITEIT UTRECHT", "ASTON UNIVERSITY", "CENTRE EUROPEEN DE RECHERCHE EN BIOLOGIE ET MEDECINE", "ART PHOTONICS", "M-SQUARED LASERS LIMITED", "GLUCOSET AS", "FUDAN UNIVERSITY", "EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY"], "EU_Contribution": ["EUR 1 269 000"], "Project_Title": ["Transcribing the processes of life: Visual Genetics"], "Total_Cost": ["EUR 1 269 000"], "Country": ["United Kingdom", "Hungary", "Hungary", "Germany", "Germany", "Netherlands", "United Kingdom", "France", "Germany", "United Kingdom", "Norway", "China", "China"], "Project_ACR": ["VISGEN"], "Technology_Description": "The Visual Genetics (VISGEN) consortium brings together eight academic and five commercial scientifically leading teams to address the unique challenge of visualizing nuclear processes in intact brain in real-time. By exchanging knowledge between academic and commercial sectors in Europe, as well as undertaking training secondments at leading Universities in China the team will grow its European and global competitiveness in a world-leading forefront of neuroscience and genetic technology. Visualisation of transcription in living systems has not been witnessed directly, this multidisciplinary and international project will herald a new era where this idea becomes a regular research tool and translates to a clinical and diagnostic technology in the future. The team will use a unique biotagging platform to develop the technology that is required to interrogate transcription. The intersectoral effort requires the amalgamation of knowledge from neuroscientists, synthetic chemists, engineers, physicists, analytical chemists, nanobiologists, behavioural scientists, laser technology and image processing experts. The consortium combines expertise from thirteen organisations from seven countries to build the multidisciplinary team and share the knowledge that addresses and will overcome the task of realising real-time and spatially resolved genetic studies. Once developed, the technology can be utilized for other medical-based research and development projects aimed at early stage disease diagnosis, cancer detection, and toxicity studies. Real-time visual genetics will transform our understanding of the state-of-the-art and herald transformative changes in the field of neuroscience, and in general life science.", "To": ["2021-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-03-01"], "Project_ID": ["734862"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["UNIVERSITETET I OSLO", "FREIE UNIVERSITAET BERLIN", "FONDATION NATIONALE DES SCIENCES POLITIQUES", "INSTITUT FUER HOEHERE STUDIEN - INSTITUTE FOR ADVANCED STUDIES", "INSTITUTE OF SOCIOLOGY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC PUBLIC RESEARCH INSTITUTION", "UNIWERSYTET JAGIELLONSKI", "UNIVERSITEIT ANTWERPEN", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "UNIVERSITEIT TWENTE"], "EU_Contribution": ["EUR 3 873 718,80"], "Project_Title": ["The Post-crisis Legitimacy of the European UnionEuropean Training Network"], "Total_Cost": ["EUR 3 873 718,80"], "Country": ["Norway", "Germany", "France", "Austria", "Czech Republic", "Poland", "Belgium", "United Kingdom", "Netherlands"], "Project_ACR": ["PLATO"], "Technology_Description": "Is there a crisis in the legitimacy of the European Union? That research question is timely and important. Investigating it is also an ideal way of training research leaders of tomorrow to rethink our assumptions about the study of legitimate political order. Whilst, however, the financial crisis has raised new questions about the legitimacy of the EU, existing theories of legitimacy crises are largely based on single-state political systems. New theory is, therefore, needed to understand what would count as legitimacy crises in the case of a non-state political system such as the EU. PLATO\u2019s (The Post-Crisis Legitimacy of the EU) ESRs will work together as a team to build new theory from 15 investigations into different standards and actors with whom the EU may need to be legitimate. ESRs will go well beyond the state-of-the-art by building a theory of legitimacy crisis in the EU from a uniquely interdisciplinary understanding of how democracy, power, law, economies and societies all fit together with institutions within and beyond the state to affect the legitimacy of contemporary political order. By developing the analytical tools needed to understand a core predicament in which the EU may both need to develop legitimate forms of political power beyond the state and find those forms of power hard to achieve, PLATO will train ESRs with the conceptual clarity needed to define new research questions at the very frontiers of their disciplines and the methodological skills needed to research those questions. They will also be prepared for careers in the non-academic sector (policy-advice, consulting, civil society, European institutions and expert bodies). PLATO\u2019s ambitious cross-university, cross-country and cross-sectoral programme of research training, supervision and secondments will pool resources from a unique network of 9 research-intensive universities and 11 non-academic partners who are themselves key users of state-of-the-art social science research.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["722581"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["UNIVERSITAET ZU KOELN", "STOCKHOLMS UNIVERSITET", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "GOETEBORGS UNIVERSITET", "MEDICAL RESEARCH COUNCIL", "UNIVERSITE DE GENEVE", "STICHTING KATHOLIEKE UNIVERSITEIT", "UNIVERSITY OF NEWCASTLE UPON TYNE", "KHONDRION BV"], "EU_Contribution": ["EUR 3 920 630,04"], "Project_Title": ["Regulation of mitochondrial expression"], "Total_Cost": ["EUR 3 920 630,04"], "Country": ["Germany", "Sweden", "Germany", "Sweden", "United Kingdom", "Switzerland", "Netherlands", "United Kingdom", "Netherlands"], "Project_ACR": ["REMIX"], "Technology_Description": "Mitochondria are essential organelles found in every eukaryotic cell, required to convert food into usable energy. The mitochondrial oxidative phosphorylation (OXPHOS) system, which produces the majority of cellular energy in the form of ATP, is controlled by two distinct genomes: the nuclear and the mitochondrial genome (mtDNA). Mutations in mitochondrial genes encoded by either genome could cause diseases affecting OXPHOS system, called mitochondrial diseases, whose prevalence has been estimated to be \u22481:8500. Moreover, dysfunction of mitochondrial OXPHOS system has emerged as a key factor in a myriad of \u201ccommon\u201d diseases, including neurodegenerative and metabolic disorders like Parkinson\u2019s and Alzheimer\u2019s Disease, Type 2 Diabetes, and was linked to aging process. Despite all this, it is surprising that our understanding of the mechanisms governing the mitochondrial gene expression and its associated pathologies remain superficial and therapeutic interventions unexplored. The basic machineries for mtDNA replication, mtDNA transcription and mitochondrial translation are known, but the regulation of these processes in response to metabolic demands is poorly understood. The complex nature of mitochondrial gene expression that relies on two different genomes calls for a multidisciplinary approach where different teams of researchers join forces. Studies in this area are not only of basic scientific interest but may also provide new avenues towards treatment of mitochondrial dysfunction in a variety of human diseases.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-10-01"], "Project_ID": ["721757"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "ETHNIKO IDRYMA EREVNON", "STICHTING OAPEN*OPEN ACCESS PUBLISHING IN EUROPEAN NETWORKS", "STIFTUNG DEUTSCHE GEISTESWISSENSCHAFTLICHE INSTITUTE IM AUSLAND - DGIA", "GEORG-AUGUST-UNIVERSITAT GOTTINGENSTIFTUNG OFFENTLICHEN RECHTS", "UBIQUITY PRESS LIMITED", "OPEN BOOK PUBLISHERS COMMUNITY INTEREST COMPANY", "DIGITAL RESEARCH INFRASTRUCTURE FOR THE ARTS AND HUMANITIES", "UNIVERSITA DEGLI STUDI DI TORINO"], "EU_Contribution": ["EUR 1 997 878,13"], "Project_Title": ["High Integration of Research Monographs in the European Open Science infrastructure"], "Total_Cost": ["EUR 1 997 878,13"], "Country": ["France", "Greece", "Netherlands", "Germany", "Germany", "United Kingdom", "United Kingdom", "France", "Italy"], "Project_ACR": ["HIRMEOS"], "Technology_Description": "HIRMEOS will improve five important publishing platforms for the open access monographs in the SSH and enhance their technical capacities and services, rendering technologies and content interoperable and embedding them fully into the European Open Science Cloud. The project focuses on the monograph as a significant mode of scholarly communication in the SSH and tackles the main obstacles of the full integration of important platforms supporting open access monographs and their contents. HIRMEOS will prototype innovative services for monographs in view of full integration in the European Open Science Cloud by providing additional data, links and interactions to the documents, paving the way to new potential tools for research assessment, which is still a major challenge in the SSH. The platforms participating (OpenEdition Books, OAPEN Library, EKT Open Book Press, Ubiquity Press and G\u00f6ttingen University Press ) will be enriched with tools that enable identification, authentication and interoperability (DOI, ORCID, Fundref), and tools that enrich information and entity extraction (INRIA (N)ERD), the ability to annotate monographs (Hypothes.is), and gather usage and alternative metric data. HIRMEOS will also enrich the technical capacities of the Directory of Open Access Books (DOAB), a most significant indexing service for open access monographs globally, to receive automated information for ingestion, while it will also develop a structured certification system to document monograph peer-review. Partners will develop shared minimum standards for their monograph publications, such that allow the full embedding of technologies and content in the European Science Cloud. Finally, the project will have a catalyst effect in including more disciplines into the Open Science paradigm, widening its boundaries towards the SSH.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["EINFRA-22-2016 - User-driven e-infrastructure innovation"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations", "Other", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["731102"], "Call_for_Proposal": ["H2020-EINFRA-2016-1"]}, -{"Partners": ["KAROLINSKA INSTITUTET"], "EU_Contribution": ["EUR 173 857,20"], "Project_Title": ["Self and others in the sensorimotor system: a computational neuroanatomy of sensory attenuation"], "Total_Cost": ["EUR 173 857,20"], "Country": ["Sweden"], "Project_ACR": ["TICKLE ME"], "Technology_Description": "Why can\u2019t you tickle yourself? Previous behavioural and neuroimaging evidence suggests that when we move one hand to touch the other, the resulting tactile sensation is perceived as less intense compared to identical touches of external origin. This sensory attenuation (SA) phenomenon is hypothesized to arise because our brains use internal information about the motor command (efference copy) to predict the tactile consequences of the movement and attenuate the tactile feedback based on these predictions. However, little is known about how the brain produces SA. \u2018TICKLE ME\u2019 combines, for the first time, computational motor control theory, force perception behavioural experiments, and state-of-the-art neuroimaging methods to address how the human brain distinguishes between self-generated and externally-generated touch.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["704438"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Stable Crosslinked Graphene Membranes for Water and Molecular Separation"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["StaGraM"], "Technology_Description": "With less than 1 percent of drinkable water on Earth and growing pollution the demand for drinking water can only be met through the advanced separation and purification technology. Membrane-based filtration technologies are standard separation processes and are widely used in water treatment; however their performance is still severely limited due to their underperformance in terms of flux, selectivity, porosity, cleaning ability, and stability. Recent advancement in nanostructured membranes based on layered graphene construct enables a paradigm shift in the membrane development due to its almost zero resistance for water molecules and 100% rejection of other components. Recent reports suggest that an ideal membrane could be realized using graphene because of its atomic thickness, high mechanical strength, and chemical inertness. Although the graphene based membranes showed excellent separation performance; unfortunately their durability and stability is the biggest obstacle in realization of its full potential. ", "To": ["2019-08-08, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-09"], "Project_ID": ["707220"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["AARHUS UNIVERSITET", "UNIVERSITEIT LEIDEN", "HERIOT-WATT UNIVERSITY", "UNIVERSITE PAUL SABATIER TOULOUSE III", "THE UNIVERSITY OF LIVERPOOL", "WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER", "UNIVERSITAET ZU KOELN", "STICHTING KATHOLIEKE UNIVERSITEIT", "GRAPHIC SCIENCE LIMITED"], "EU_Contribution": ["EUR 4 009 451,64"], "Project_Title": ["The Extensive and Ubiquitous Role of Polycyclic Aromatic Hydrocarbons (PAHs) in Space"], "Total_Cost": ["EUR 4 009 451,64"], "Country": ["Denmark", "Netherlands", "United Kingdom", "France", "United Kingdom", "Germany", "Germany", "Netherlands", "United Kingdom"], "Project_ACR": ["EUROPAH"], "Technology_Description": "Large Polycyclic Aromatic Hydrocarbon (PAH) molecules are deeply interwoven in the fabric of the Universe and lock up ~15% of the elemental carbon in the interstellar medium (ISM) of galaxies. They dominate the mid-infrared emission characteristics of galaxies that can be used to trace star formation locally as well as in the early universe, they influence the phase structure of the ISM and the star formation rate of galaxies, and they are the epitome of molecular complexity in space, heralding the importance of top-down chemistry. In spite of the influential role of PAHs in the ISM, their lifecycle, catalytic activity, interaction with interstellar radiation, gas and grains and their role in the organic inventory of solar system bodies is still poorly understood. The EUROPAH ETN aims to change this by creating a highly multidisciplinary network that combines astronomy, molecular physics, molecular spectroscopy, environmental science, quantum chemistry, surface sciences, and plasma physics in a comprehensive research and training program. EUROPAH will train 16 ESRs through cutting edge individual research and innovation projects investigating key physical and chemical processes of PAHs in space and related terrestrial settings and linking directly to R&D needs of our industrial beneficiaries. EUROPAH will engage all ESRs in industry driven innovation activities aimed at R&D of the industrial participants products and services, including outreach activities led by our industrial science communication beneficiary. Research and innovation training is complemented by an extensive program of network-wide training events to expose ESRs to all disciplines in the network and to instill in them a comprehensive set of transferable skills. This will provide the ESRs with a unique learning environment in a multidisciplinary setting aimed at developing a research oriented creative and innovative mind set and will place them well for a future career in academia or in industry.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-10-01"], "Project_ID": ["722346"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["NATIONAL UNIVERSITY OF IRELAND GALWAY", "UNIVERSITAET REGENSBURG", "RIJKSUNIVERSITEIT GRONINGEN", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "ERNST-MORITZ-ARNDT-UNIVERSIT\u00c4T GREIFSWALD", "UMEA UNIVERSITET", "NATAC BIOTECH SL", "UNIVERSITY OF DUNDEE", "NIZO FOOD RESEARCH BV", "UNIVERSITY OF NEWCASTLE UPON TYNE", "NESTEC S.A"], "EU_Contribution": ["EUR 3 385 026,36"], "Project_Title": ["Training Network to Understand and Exploit Mechanisms of Sensory Perception in Bacteria"], "Total_Cost": ["EUR 3 385 026,36"], "Country": ["Ireland", "Germany", "Netherlands", "Spain", "United Kingdom", "Germany", "Sweden", "Spain", "United Kingdom", "Netherlands", "United Kingdom", "Switzerland"], "Project_ACR": ["PATHSENSE"], "Technology_Description": "The PATHSENSE (Pathogen Sensing) ETN will bring together an interdisciplinary team of world-leading researchers from Europe to tackle a highly ambitious scientific project, focusing on the molecular mechanisms of sensory perception in bacterial pathogens. PATHSENSE will establish an innovative doctoral training programme that will deliver 13 PhD graduates and high-impact scientific outputs. The relationship between molecular structures and biological function is central to understanding any living system; however the research methodologies required to unravel these relationships are often complex and fast-changing. The team participating in this Network has the infrastructure and track-record to train ESRs in these state-of-the art methodologies, including structural biology, proteomics & protein biochemistry, molecular biology, bacterial genetics, food microbiology, mathematical modelling, cell biology, microscopy and comparative genomics. PATHSENSE will investigate the poorly understood structure-function relationships that exist within a large multi-protein complex called a \u201cstressosome\u201d, which acts as a sensory organelle in bacteria. The project will involve extensive inter-sectoral mobility of the ESRs across 7 EU countries to make full use of the complementary skills available at each of the hosting institutions. The inter-sectoral Network comprises 8 leading Universities, 1 public research institution, 4 companies (from spin-off to large multi-national) and 1 governmental agency. A major objective of this Network will be to exploit the fundamental research to develop novel antimicrobial treatments that have applications in the food and public health sectors. This project will deliver high-impact science, 13 highly-trained innovative researchers and will produce a long-lasting inter-sectoral network of collaborators who will continue to work together to exploit fundamental research for the socio-economic benefit of Europe.", "To": ["2021-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-04-01"], "Project_ID": ["721456"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM", "UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 2 493 318"], "Project_Title": ["A Unified Framework for the Assessment and Application of Cognitive Models"], "Total_Cost": ["EUR 2 493 318"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["UNIFY"], "Technology_Description": "Cognitive models formalize substantive theory about how people reason, learn, decide, and act. Cognitive models also serve as measurement tools that explain observed behavior in terms of constituent psychological processes. Because of their unique ability to estimate latent processes, cognitive models are increasingly applied throughout cognitive neuroscience and clinical psychology. Despite their theoretical appeal and growing popularity, however, the field of cognitive modeling presents an often bewildering proliferation of ideas and techniques. Current applications appear idiosyncratic, and the state-of-the-art remains unclear. This lack of systematicity makes it difficult for researchers and practitioners to develop, understand, and apply important cognitive models.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["743086"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "ETHNIKO IDRYMA EREVNON", "STICHTING OAPEN*OPEN ACCESS PUBLISHING IN EUROPEAN NETWORKS", "STIFTUNG DEUTSCHE GEISTESWISSENSCHAFTLICHE INSTITUTE IM AUSLAND - DGIA", "KNOWLEDGE UNLATCHED CIC"], "EU_Contribution": ["EUR 408 586,25"], "Project_Title": ["Design for Open access Publications in European Research Areas for Social Sciences and Humanities"], "Total_Cost": ["EUR 408 586,25"], "Country": ["France", "Greece", "Netherlands", "Germany", "United Kingdom"], "Project_ACR": ["OPERAS-D"], "Technology_Description": "OPERAS-D (Design) project will support the 5 main partners (\u201ccore group\u201d) of the OPERAS network in the development of a European e-infrastructure for open access publications in the Social Sciences and Humanities (SSH). The project will address long-term requirements for the development of the e-infrastructure and community building, as well as seek to expand other interested parties within and beyond Europe, and in diverse fields of the SSH. ", "To": ["2018-06-30, ongoing project"], "Meta": [""], "Topic_s": ["INFRASUPP-03-2016 - Support to policies and international cooperation for e-infrastructures"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations", "Other", "Research Organisations", "Other"], "From": ["2017-01-01"], "Project_ID": ["731031"], "Call_for_Proposal": ["H2020-INFRASUPP-2016-1"]}, -{"Partners": ["\"NATIONAL CENTER FOR SCIENTIFIC RESEARCH \"\"DEMOKRITOS\"\"\"", "NATIONAL OBSERVATORY OF ATHENS", "HELLENIC CENTRE FOR MARINE RESEARCH", "ETHNIKO IDRYMA EREVNON", "ATHINA-EREVNITIKO KENTRO KAINOTOMIAS STIS TECHNOLOGIES TIS PLIROFOFORIAS, TON EPIKOLNONION KAI TIS GNOSIS", "IDRIMA MEIZONOS ELLINISMOU", "EPISTIMI EPIKOINONIA"], "EU_Contribution": ["EUR 160 000"], "Project_Title": ["REsearchers' Nights organized by Athens area Research Institutions to convey the science benefits to the public and motivate young people to science careers"], "Total_Cost": ["EUR 160 000"], "Country": ["Greece", "Greece", "Greece", "Greece", "Greece", "Greece", "Greece"], "Project_ACR": ["RENA"], "Technology_Description": "A diverse team of experts in scientific research and science communication from leading Research Institutes and Educational Organizations, located in the Athens Metropolitan area, is formed to organize the Researcher's Night activities for the years 2016 and 2017. By adopting the concept \u201cScience invites People\u201d, we propose a large scale REN, in 2016, at NCSR \"Demokritos\", the largest Science Research campus in Greece, and a similar event in 2017 at at the Foundation of the Hellenic World, a multiplex where science meets entertainment and exploration, organized by the National Observatory of Athens.", "To": ["2017-11-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-NIGHT-2016 - European Researchers' Night"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Greece"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Other"], "From": ["2016-05-01"], "Project_ID": ["722973"], "Call_for_Proposal": ["H2020-MSCA-NIGHT-2016"]}, -{"Partners": ["SABANCI UNIVERSITESI"], "EU_Contribution": ["EUR 251 053,20"], "Project_Title": ["A Mechanism Design and Cheap Talk Approach to Mediation"], "Total_Cost": ["EUR 251 053,20"], "Country": ["Turkey"], "Project_ACR": ["Mediation"], "Technology_Description": "Mediation is an alternative dispute resolution (ADR) technique. If two or more parties are in disagreement, then they can take the case to a court and let the judge give the final decision. Alternatively, the disputing parties can get the help of an experienced, neutral third party (i.e., the mediator) who facilitates a negotiation and help the disagreeing parties reach an agreement short of litigation. The mediation process is private and confidential, possibly enforced by law (European Mediation Directive 2008). The rising popularity of mediation can be explained by the increasing workload of courts, by the fact that mediation is less costly than litigation, and by the desire of some control over the final decision.", "To": ["2018-07-31, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Turkey"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-08-01"], "Project_ID": ["659780"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["LUNDS UNIVERSITET", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSITAETSMEDIZIN GOETTINGEN - GEORG-AUGUST-UNIVERSITAET GOETTINGEN - STIFTUNG OEFFENTLICHEN RECHTS", "DEUTSCHES ZENTRUM FUR NEURODEGENERATIVE ERKRANKUNGEN EV", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "EXPLORA NOVA SARL", "UMECRINE AB"], "EU_Contribution": ["EUR 3 129 428,16"], "Project_Title": ["Synaptic dysfunction in Neurodegenerative Diseases"], "Total_Cost": ["EUR 3 129 428,16"], "Country": ["Sweden", "United Kingdom", "France", "Germany", "Germany", "Switzerland", "France", "Sweden"], "Project_ACR": ["SYNDEGEN"], "Technology_Description": "Neurodegenerative diseases (NDDs) of aging are a growing burden on societies. Although studies on the degeneration of neurons have been a main focus of research, increasing evidence points to synapses as the site where Alzheimer\u2019s disease (AD), Parkinson\u2019s disease (PD) and Huntington\u2019s disease (HD) begin. There is growing evidence that synapses are sites of early and aberrant protein misfolding, aggregation and spread in NDDs. A key problem in research on NDDs has been that the normal physiological roles at synapses of the aggregation-prone proteins (\u03b2- amyloid/amyloid precursor protein, tau, \u03b1-synuclein and huntingtin), which are linked pathologically and genetically to these diseases, are not known. Using cutting-edge technologies and multidisciplinary approaches the SYNDEGEN consortium aims to bring together leading experts in cell biology, synapse biology and imaging, stem cell biology and NDDs in Europe to determine the molecular and cellular mechanisms whereby synapses become dysfunctional in AD, PD and HD for the purpose of developing novel therapies. The goal of the consortium is to train talented young scientists in interdisciplinary, innovative and collaborative research aimed at the development of novel molecular based treatment strategies for these major diseases of aging. A gap in the training of students in these important diseases is that disease expertise and novel methods to study synapses are localized in isolated groups in different locations in the EU. Similar questions are being asked about the mechanisms of synaptic dysfunction in AD, PD and HD, but no one university or company has sufficiently broad knowledge and technical expertise required to study and develop therapies for synaptic dysfunction in these disorders. This training programme will be implemented in 6 academic centres and 2 SMEs representing a comprehensive, highly interactive and multidisciplinary partnership.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["721802"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["LUNDS UNIVERSITET", "TECHNISCHE UNIVERSITAET DRESDEN", "LINNEUNIVERSITETET", "MOLECULAR SENSE LTD", "BAR ILAN UNIVERSITY", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V."], "EU_Contribution": ["EUR 6 084 949"], "Project_Title": ["Parallel network-based biocomputation: technological baseline, scale-up and innovation ecosystem"], "Total_Cost": ["EUR 6 084 949"], "Country": ["Sweden", "Germany", "Sweden", "United Kingdom", "Israel", "Germany"], "Project_ACR": ["Bio4Comp"], "Technology_Description": "Many technologically and societally important mathematical problems are intractable for conventional, serial computers. Therefore, a significant need exists for parallel-computing approaches that are capable to solve such problems within reasonable time frames. Recently, part of our consortium demonstrated proof-of-principle of a parallel-computation system in which a given combinatorial problem is encoded into a graphical, modular network that is embedded in a nanofabricated planar device. The problem is then solved by a large number of independent biological agents, namely molecular-motor-propelled protein filaments, exploring the network in a highly parallel fashion (PNAS 113, 2591 (2016)). Notably, this approach uses orders of magnitude less energy than conventional computers, thus addressing issues related to power-consumption and heat-dissipation. Within Bio4Comp we (i) will establish the technological and scientific basis for robust upscaling of this approach, (ii) will demonstrate scalability by systematically increasing the problem size by several orders of magnitude, and (iii) will develop new algorithms with the aim to open up a wide range of applications. Additionally, we will (iv) help foster and structure an ecosystem of scientists and companies that will accelerate the path to market acceptance, including the creation of a joint roadmap. Benefits to society will include the ability to solve hitherto intractable problems, and the development of a sustainable and energy-efficient computing approach that is radically different from current information and communications technology.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["FETPROACT-01-2016 - FET Proactive: emerging themes and communities"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2017-01-01"], "Project_ID": ["732482"], "Call_for_Proposal": ["FETPROACT-2016"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 264 668,40"], "Project_Title": ["Understanding the Commitment in Organized Crime"], "Total_Cost": ["EUR 264 668,40"], "Country": ["France"], "Project_ACR": ["UCOC"], "Technology_Description": "This project is structured around a central question: how do individuals get involved in organized crime? To answer it, the analysis will focus on the social conditions of the criminal commitment and promotion towards superior spheres of drug trafficking. I will use the notion of \u201ccriminal career,\u201d increasing and updating the existing knowledge on the steps that allow an upward social mobility. This problematic implies first to describe and analyze the universe of organized crime, its subdivisions, its hierarchies, its divides, and the structure of its opportunities. Then, it also necessary to put the framework of the biographical trajectories into a historical, social and political perspective. ", "To": ["2021-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2018-03-01"], "Project_ID": ["752743"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["HASKOLI ISLANDS", "UNIVERSITAET BREMEN", "THE OPEN UNIVERSITY", "TECHNISCHE UNIVERSITAET WIEN", "FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG", "UNIVERSITETET I OSLO", "UNIVERSITAET BIELEFELD", "TECHNISCHE UNIVERSITEIT DELFT", "EIDGENOSSISCHE MATERIALPRUFUNGS- UND FORSCHUNGSANSTALT", "STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN", "INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM", "TESCAN BRNO SRO", "CARL ZEISS SMT GMBH"], "EU_Contribution": ["EUR 3 878 757"], "Project_Title": ["Low energy ELEctron driven chemistry for the advantage of emerging NAno-fabrication methods"], "Total_Cost": ["EUR 3 878 757"], "Country": ["Iceland", "Germany", "United Kingdom", "Austria", "Germany", "Norway", "Germany", "Netherlands", "Switzerland", "Netherlands", "Belgium", "Czech Republic", "Germany"], "Project_ACR": ["ELENA"], "Technology_Description": "Chemistry is fundamental to nanotechnology, as chemistry can prepare specifically tailored molecules to serve, in a bottom-up approach, as the building blocks for the fabrication of functional and structured nano-materials. Nanotechnology is the technology of the 21st century with applications from electronics to biotechnology and medicine. The next decade will thus be characterized by an increasing industrial demand for novel nanostructures with individual physical and chemical properties tuned to specific applications. This, in turn, requires increased flexibility and control over material composition, shape and resolution. To meet this demand the chemistry and the physics behind new and emerging nanoscale fabrication methods must be well understood and this understanding must be systematically deployed to advance these methods into commercially viable fabrication technologies. Simultaneously to ensure that Europe is a significant player in this economically and technologically important industry, the European nanotechnology industry must have access to well trained individuals with both the technical skills and a broad understanding of the physical and chemical parameters governing the performance of next generation processing techniques and, the skills and drive needed for further innovation and entrepreneurship in the nano-technology field. ELENA addresses these scientific and training needs by: i) studying the chemistry underpinning two emerging nano-technology writing techniques; Focused Electron Beam Induced Processing and Extreme Ultra Violet Lithography, ii) exploiting knowledge gained in (i) to develop these techniques such that they may be made commercially competitive, and iii) training a new generation of European scientists with a fundamental understanding of the physics and chemistry behind these processes and the mind set for innovation and entrepreneurship to provide an exemplar for up-skilling European nanotechnology industry.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Iceland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-10-01"], "Project_ID": ["722149"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["CONSIGLIO PER LA RICERCA IN AGRICOLTURA E L'ANALISI DELL'ECONOMIA AGRARIA", "UNIVERSITA DEGLI STUDI DI MILANO", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "KWS LOCHOW GMBH", "KEYGENE NV"], "EU_Contribution": ["EUR 486 000"], "Project_Title": ["Exploring the molecular control of seed yield in crops"], "Total_Cost": ["EUR 792 000"], "Country": ["Italy", "Italy", "Spain", "Germany", "Netherlands"], "Project_ACR": ["ExpoSEED"], "Technology_Description": "ExpoSEED aims to integrate forward and reverse genetic approaches to dissect the molecular mechanisms that control seed/kernel (hereafter referred as seed) yield in model species and to transfer the acquired knowledge to selected crops as legumes and cereals. The identification of \u201cmolecular hubs\u201d that determine seed number and size will put the basis for the development of breeding tools to improve seed production at the beginning of the seed market.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-01-01"], "Project_ID": ["691109"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["KATHOLIEKE UNIVERSITEIT LEUVEN"], "EU_Contribution": ["EUR 160 800"], "Project_Title": ["Multifunctional Cellulose Magnetic Hybrid (CMH) Nanomaterial for Integrating Downstream Processing of Microalgae"], "Total_Cost": ["EUR 160 800"], "Country": ["Belgium"], "Project_ACR": ["CMHAlgae"], "Technology_Description": "Microalgae are a promising new biomass source for the production of chemicals and biofuel. Notwithstanding extensive R&D efforts, the cost and energy demand the production process remain too high, particularly in downstream processing. We believe the efficiency of microalgae downstream processing can be greatly improved through the use of nanotechnology. Hybrid and/or multifunctional nanoparticles can be tailored with multiple functional groups to combine several unit operations in a single technology. In this project, we combine expertise on Fe3O4 nanomaterials and cell disruption technologies from the experienced researcher with expertise of the two co-supervisors in nanocellulose materials and microalgae harvesting to create a bio-based and re-usable Cellulose Magnetic Hybrid (CMH) nanomaterial for downstream processing of microalgae. As a basis we will use nanocellulose, a natural material that can easily be grafted with multiple functional groups. The nanocellulose will be equipped with quaternary ammonium groups to generate flocculating and cell disruption activity, as well as pH-responsive to allow detachment of the nanomaterial after processing. The nanocellulose will be linked to an Fe3O4 nanoparticles, which will allow separating the microalgal biomass from the medium as well as recovery of the nanomaterial after downstream processing. Thus, our CMH nanomaterial will be capable of combined flocculation, dewatering and cell disruption of microalgae and can be removed from the biomass and re-used after processing. The techno-economic feasibility of this novel technology will be demonstrated in two model systems: lipid production in Nannochloropsis and astaxanthin production in Haematococcus. We believe that this CMH nanomaterial will be able to achieve a critical cost reduction in microalgal downstream processing and truly advance large-scale microalgae biomass production towards commercialization.", "To": ["2019-08-01, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-02"], "Project_ID": ["751637"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 212 194,80"], "Project_Title": ["Regulation and Metabolic Engineering of Saponins for use as bio-pesticides."], "Total_Cost": ["EUR 212 194,80"], "Country": ["Denmark"], "Project_ACR": ["REMES"], "Technology_Description": "Insect pests and pathogens cause major losses in agriculture, and there is a critical need to develop novel and sustainable methods to reduce these losses. Plants produce a vast diversity of specialized chemicals that deter antagonist, but in spite of their potential for pest management they are still largely unexplored. We need to understand better how such defence compounds are synthesized by plants and what biotic and abiotic conditions trigger and regulate their production, in order to develop and use them sustainably. The objective of my REMES project is to uncover the genetic and molecular regulation of triterpenoid saponin biosynthesis, using the insect-resistant wild crucifer Barbarea vulgaris as a model system, and explore their use as bio-pesticides. I will 1) characterize transcriptional regulators of the saponin biosynthetic pathway; 2) explore how saponin biosynthesis responds to different functional types of insects and pathogens in B. vulgaris; and 3) manipulate the regulatory responses and production of saponins to assess their potential as sustainable bio-pesticides. In the project, I will take advantage of the experience and state-of-the-art facilities at the host in systems biology, molecular biology, biochemistry, bioinformatics, metabolomics and plant-insect interactions; in turn, I will contribute my own expertise in characterization of transcriptional regulation of specialized metabolism in plants. With the project I will consolidate my career in research whilst also developing important academic and transferrable skills for pursuing a future career in academia. Altogether, the project will improve our understanding of saponin biosynthesis and regulation, which will improve the industrial interest and means to develop crops with modified content of saponins and ecologically appropriate defence reactions, either through classical breeding or genetic engineering.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["752437"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Defining the immunological interplay between fibroblastic reticular cells and anti-tumour T cells"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["FIBROCAN"], "Technology_Description": "Lymph nodes are sites where immune responses are robustly initiated. Paradoxically, they are also very common metastatic sites, where tumour progression is well-tolerated. Robust evidence defines a role for fibroblastic reticular cells (FRCs) in preventing T cells from acquiring effector functions within lymph nodes, and deleting T cells that show self-reactivity. FIBROCAN will test the hypothesis that FRCs systematically shut down anti-tumour T cell responses, testing mechanisms of suppression in vitro and in vivo, and charting tumour antigen presentation by FRCs to T cells for the first time. ", "To": ["2018-06-30, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-07-01"], "Project_ID": ["707525"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["STICHTING KATHOLIEKE UNIVERSITEIT", "STICHTING KATHOLIEKE UNIVERSITEIT"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["A biomechanically driven, patient specific pre-planning and surgical tool to optimize placement of a novel meniscus prosthesis"], "Total_Cost": ["EUR 150 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["BioMechMeniscus"], "Technology_Description": "In this BioMechMeniscus project we will develop a workflow for optimal placement of a novel meniscus implant. The medial meniscus implant (named \u2018Trammpolin\u2019) has been developed using methods developed during the BioMechTools project such as 1) principle component analyses based on MRI-segmented image to assess the anatomical shape of the meniscus, 2) assessing sensitivity of cartilage stresses and implant strains on size and design-parameters using finite element techniques and 3) utilizing load-predictions from our award-winning musculoskeletal models. ", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["768338"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Situating the New Urban University: Higher Education in an Era of Global Urbanization"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["NEW URBAN UNIVERSITY"], "Technology_Description": "The global impact of urbanization presents unprecedented opportunities and profound challenges for universities. It significantly impacts the expectations placed on universities and where in the world \u2013 and the city \u2013 they need to adapt their institutional infrastructures, pedagogical practices and ways of operating. The multiscalar networks of global urbanization mean urban universities must be understood as being more than simply located \u2018in the city\u2019. The \u2018new urban university\u2019 is regionalizing and globalizing in dramatic, chaotic ways. What capacities do universities have as urban leaders in a globalizing world? How can universities better mobilize in, and for, extended city-regions? How can marginalized urban communities inform universities\u2019 spatial and strategic actions? Situating the New Urban University responds to the challenges of global urbanization by illustrating how higher education providers can better serve people in places, versus drawing people to a place. By taking stock of the influence major sociospatial changes in urban regions have on universities (e.g. globalization, neoliberalization), the project: (1) provides an international assessment of universities\u2019 engagement practices and impacts; and (2) presents a major comparative examination of higher education systems at the city-regional scale. In-depth studies of universities\u2019 spatial strategies in the London and New York global city-regions will speak directly to best practices in creating and sustaining reflexive, resilient university-society networks for diverse communities in urban contexts. Stakeholder involvement from the initial phases of the research allows the project to integrate direct input from in the research design and outputs. Situating the New Urban University deepens academic and policy understandings of how knowledge transfer takes place in global city-regions, enabling higher education and urban policymakers to optimize universities\u2019 contributions and societal impact.", "To": ["2017-09-30, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["657522"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Large Deviations and Measure Rigidity in Dynamics"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["LDMRD"], "Technology_Description": "The proposition aims to develop new tools in ergodic theory and dynamical systems, and explore applications to problems related to mathematical physics, geometry and arithmetics. The first general objective is to advance large deviation theory for non-compact dynamical systems. We plan to deduce new subexponential large deviation bounds for Gibbs measures on the countable Markov shift and explore how these results are linked to applications such as Pomeau-Manneville dynamics describing intermittence in the theory of turbulent flows, dynamical properties of the Gauss map, which is deeply connected to Diophantine approximation, and homogeneous dynamics such as the Teichm\u00fcller flow on translation surfaces. The second general objective is to investigate Host-type measure rigidity theory for toral automorphisms and homogeneous dynamics. This topic relates to currently ongoing research on measure classification theorems, which have been influential in several applications such Diophantine approximation and quantum ergodicity.", "To": ["2017-08-31, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["655310"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["Synthetic magnetism with ultracold Fermi gases of strontium"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["SYMULGAS"], "Technology_Description": "Since the first observation of a gaseous Bose Einstein condensate , ultracold atoms have provided a unique perspective into the quantum world. In a few seconds a piece of hot metal is transformed into an extremely dilute, nanokelvin gas, which is governed by quantum statistics - a new state of matter. Quantum gases are so versatile that with the same apparatus one can, for example, explore superfluidity and ultracold chemical reactions, or even search for changes in fundamental constants . A new frontier of physics, with multidisciplinary appeal, explores topological states of matter, such as the ones predicted to emerge when quantum gases are immersed in a synthetic gauge field.", "To": ["2017-07-31, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-08-01"], "Project_ID": ["661171"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["KING'S COLLEGE LONDON"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Logical and Psychological Foundations for a Teleosemantic Theory of Productivity"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["TeleoLogic"], "Technology_Description": "How can we understand sentences we\u2019ve never heard before? What distinguishes meaningful things from nonmeaningful things? These questions pose the problems of productivity and intentionality, respectively. ", "To": ["2019-08-31, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["741316"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["AGENZIA NAZIONALE PER LE NUOVE TECNOLOGIE, L'ENERGIA E LO SVILUPPO ECONOMICO SOSTENIBILE", "THE QUEEN'S UNIVERSITY OF BELFAST", "THE UNIVERSITY OF WARWICK", "CALIFORNIA INSTITUTE OF TECHNOLOGYCORP"], "EU_Contribution": ["EUR 342 000"], "Project_Title": ["BIaxial STRETCHing of PLLA-WS2 nanocomposites FOR thinner and stronger BIOMEDical scaffolds"], "Total_Cost": ["EUR 400 500"], "Country": ["Italy", "United Kingdom", "United Kingdom", "United States"], "Project_ACR": ["Bi-Stretch-4-Biomed"], "Technology_Description": "New materials are now opening clinical treatments in which a temporary scaffold is used to support regeneration of healthy tissue. The specific need that inspires our research is for thinner and stronger bioresorbable vascular scaffolds (BVS) for coronary heart disease. BVS are poised to replace metal stents due to the excellent clinical outcomes: beyond keeping the vessel open during the first six months after surgery, the BVS leaves behind a healthy blood vessel after the scaffold is gone, being completely absorbed by the body approximately two years after surgery. The material that has achieved clinical approval for BVS is poly(L-lactic acid), PLLA. It is not as strong and stiff as metals, so the scaffold is three times thicker than the metal stents, making it more difficult for surgeons to move through arteries to reach the site of the lesion. Thinner Scaffolds that can be seen by x-ray imaging during surgery would facilitate adoption of the technology and benefit thousands of patients in the EU and US. The proposed Action will provide the fundamental understanding needed to reinforce PLLA by tungsten disulphide (WS2) nanotubes to achieve both the strength and x-ray opacity needed. Improving materials for BVS requires an interdisciplinary approach by materials science, polymer processing, and bioengineering. The proposed Action will connect EU scientists with a polymer scientist at Caltech in the US who has specialized knowledge of PLLA BVS and the relevant structure-processing-property relationships (Kornfield). European scientists bring expertise in WS2 nanotubes that are powerful additives for enhancing polymer properties (Di Luccio), compounding polymers with nanotubes (McNally), biaxial stretching to induce strength and orientation in polymers (Menary), multiscale modeling to connect nanoscale to continuum scale (Figiel), multimethod characterization of structure in nanocomposites (Schiller) and the response of cells to nanoparticles (Kornfield).", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-02-01"], "Project_ID": ["691238"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["UNIVERSITY OF WOLVERHAMPTON", "NOTTINGHAMSHIRE HEALTHCARE NHS FOUNDATION TRUST", "ALZHEIMER EUROPE", "UNIVERSITE DU LUXEMBOURG", "UNIVERSITEIT TWENTE", "STICHTING ZORGGROEP SINT MAARTEN", "PANTON BV", "TECHNISCHE UNIVERSITAET DRESDEN", "ALEXIANER ST. HEDWIG KLINIKEN BERLIN GMBH", "FUNDACIO EURECAT", "PIBARQUITECTURASIX SLP", "FUNDACION INTRAS", "UNIVERSITAT POLITECNICA DE CATALUNYA", "DU IT SOCIETA A RESPONSABILITA LIMITATA", "QUEENSLAND UNIVERSITY OF TECHNOLOGY - QLD QUT"], "EU_Contribution": ["EUR 531 000"], "Project_Title": ["Designing for People with Dementia: designing for mindful self-empowerment and social engagement"], "Total_Cost": ["EUR 535 500"], "Country": ["United Kingdom", "United Kingdom", "Luxembourg", "Luxembourg", "Netherlands", "Netherlands", "Netherlands", "Germany", "Germany", "Spain", "Spain", "Spain", "Spain", "Italy", "Australia"], "Project_ACR": ["MinD"], "Technology_Description": "This project aims to help people with dementia engage in social contexts to improve psychosocial wellbeing. People who are affected by Alzheimer\u2019s disease or other dementias often face cognitive, behavioural and psychosocial difficulties, including impairment and degeneration of memory and of perceptions of identity. In a social context, this can cause difficulties of recognizing, relating to and empathising with other people. These difficulties often pose a challenge for engaging socially, reinforcing their effects and reducing personal well-being. ", "To": ["2020-02-29, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["691001"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE", "LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE", "UNIVERSIDADE FEDERAL DA BAHIA", "UNIVERSITY OF BRISTOL", "ST GEORGE'S HOSPITAL MEDICAL SCHOOL", "MEDICAL RESEARCH COUNCIL", "Massey University"], "EU_Contribution": ["EUR 2 348 803"], "Project_Title": ["Understanding asthma phenotypes: going beyond the atopic/non-atopic paradigm"], "Total_Cost": ["EUR 2 348 803"], "Country": ["United Kingdom", "United Kingdom", "Brazil", "United Kingdom", "United Kingdom", "United Kingdom", "New Zealand"], "Project_ACR": ["AsthmaPhenotypes"], "Technology_Description": "Fifteen years ago it was widely believed that asthma was an allergic/atopic disease caused by allergen exposure in infancy; this produced atopic sensitization and continued exposure resulted in eosinophilic airways inflammation, bronchial hyper-responsiveness and reversible airflow obstruction. It is now clear that this model is at best incomplete. Less than one-half of asthma cases involve allergic (atopic) mechanisms, and most asthma in low-and-middle income countries is non-atopic. Westernization may be contributing to the global increases in asthma prevalence, but this process appears to involve changes in asthma susceptibility rather than increased exposure to \u201cestablished\u201d asthma risk factors. Understanding why these changes are occurring is essential in order to halt the growing global asthma epidemic.This will require a combination of epidemiological, clinical and basic science studies in a variety of environments. ", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["668954"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["THE UNIVERSITY OF WARWICK", "EURECOM", "UNIVERSITA DEGLI STUDI DI SASSARI", "PARIS-LODRON-UNIVERSITAT SALZBURG", "SOCIAL CURRENCIES MANAGEMENT S.L.", "XLAB RAZVOJ PROGRAMSKE OPREME IN SVETOVANJE DOO", "MICHIGAN STATE UNIVERSITY", "INSTITUTE OF AUTOMATION CHINESE ACADEMY OF SCIENCES", "UNIVERSIDADE ESTADUAL DE CAMPINAS", "HONG KONG BAPTIST UNIVERSITY", "NANYANG TECHNOLOGICAL UNIVERSITY", "SOUTH CHINA UNIVERSITY OF TECHNOLOGY", "NEW JERSEY INSTITUTE OF TECHNOLOGY", "INDRAPRASTHA INSTITUTE OF INFORMATION TECHNOLOGY DEHLI", "THE UNIVERSITY OF SYDNEY", "CENTRO DE APLICACIONES TECNOLOGICAS DE AVANZADA", "MONASH UNIVERSITY SUNWAY CAMPUS MALAYSIA SDN BHD"], "EU_Contribution": ["EUR 2 025 000"], "Project_Title": ["Computer Vision Enabled Multimedia Forensics and People Identification"], "Total_Cost": ["EUR 2 025 000"], "Country": ["United Kingdom", "France", "Italy", "Austria", "Spain", "Slovenia", "United States", "China", "Brazil", "Hong Kong", "Singapore", "China", "United States", "India", "Australia", "Cuba", "Malaysia"], "Project_ACR": ["IDENTITY"], "Technology_Description": "Forensics is a well-established science that aims at applying various disciplines to the law, both civil and criminal, in order to solve questions related to crime. It is mainly concerned with proving and investigating infringements, identifying perpetrators and describing modus operandi. Biometrics, on the other hand, is a relatively new science that aims at measuring and analysing a person's unique characteristics, both behavioural and physical. It is mainly concerned with the development of technological solutions to extract and evaluate a person's biometric data mainly for verification and identification purposes.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-01-01"], "Project_ID": ["690907"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN", "LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN", "RIJKSUNIVERSITEIT GRONINGEN"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Substrate import at work: single-molecule studies of ABC transporters"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Germany", "Germany", "Netherlands"], "Project_ACR": ["SM-IMPORT"], "Technology_Description": "ABC (ATP Binding Cassette) transporters represent the most abundant and diverse family of transport proteins known that play crucial roles in numerous cellular processes. Despite their importance, all proposed molecular models for transport are based on indirect evidence due to the inability of classical biophysical and biochemical techniques to directly visualize dynamic structural changes. To solve this problem, I suggest a novel approach that can decipher the molecular mechanisms of transport, with the ultimate goal to use this knowledge against pathogenic bacteria, for treatment of ABC-related diseases or multi-drug resistance of cancer cells.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["638536"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["FUNDACION CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Molecular mechanisms regulating cardiovascular remodeling by Adamts1"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["MERC"], "Technology_Description": "Professor Redondo\u2019s group has recently identified Adamts1 as one of the major mediators in vascular wall remodeling. They showed that Adamts1+/-, Adamts1-/- and KD-Adamts1 mice present aortic dilation, aneurysms, medial degeneration and hypotension, leading to the hypothesis that Adamts1 deficiency results in a new familial form of thoracic aortic aneurysm (FTAAD) potentially relevant in human aortic disease. They have also found that nitric oxide synthase (NOS) inhibitors reverse aortic dilation and medial degeneration in Marfan mice and Adamts1-deficient mice. The objective of my project is to study the molecular mechanisms mediating these aortic diseases in mice, and to specifically assess the role of nitric oxide (NO) and related signaling pathways, including those of Adamts1 and its substrates, in the medial degeneration and aortic dilation in both mouse models. I plan to identify potential targets common to both aortopathies and analyze them in patients with syndromic and non-syndromic aortic diseases. I think this project has a strong potential to identify therapeutic targets and prognostic or diagnostic markers for human cardiovascular diseases that constitute one of the major causes of mortality worldwide.", "To": ["2018-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2016-06-01"], "Project_ID": ["703561"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["A bird\u2019s (social) life: development and senescence in wild social networks."], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SOCIALIFE"], "Technology_Description": "Over the course of an individual\u2019s lifetime, the strength and type of social interactions change markedly with age. Because social interaction underpins many aspects of fitness, the contributions of age-related changes in social behaviour to fitness variation are a key process to understand. Yet, little work has been possible owing to the challenges of quantifying social behaviour in large numbers of individuals over their lifetimes. I thus aim at testing the hypothesis that age-related variation in social behaviour contributes to age-related changes in survival and reproduction. The project will make the most of the exceptional novel infrastructure and statistical approaches developed by my host group in Oxford to quantify and manipulate social interactions in free-living birds.", "To": ["2019-08-31, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["752084"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["EUROPEAN SOCIAL SURVEY EUROPEAN RESEARCH INFRASTRUCTURE CONSORTIUM", "EUROPEAN RESEARCH INFRASTRUCTURE CONSORTIUM FOR THE SURVEY OF HEALTH, AGEING AND RETIREMENT IN EUROPE", "CESSDA AS", "KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW", "STICHTING KATHOLIEKE UNIVERSITEIT BRABANT", "UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 8 494 397"], "Project_Title": ["Synergies for Europe's Research Infrastructures in the Social Sciences"], "Total_Cost": ["EUR 8 884 397"], "Country": ["United Kingdom", "Germany", "Norway", "Netherlands", "Netherlands", "Netherlands"], "Project_ACR": ["SERISS"], "Technology_Description": "Europe is facing huge socio-economic challenges: an economic crisis with a young generation in search of jobs, population ageing potentially straining inclusion and innovation of our societies, climate change with its pressures to redesign energy, transport and housing patterns, just to name some of the most urgent \u201cGrand Challenges\u201d. SERISS brings together three research infrastructures in the social sciences: the European Social Survey (ESS), the Survey for Health Ageing and Retirement in Europe and the Consortium of European Social Science Data Archives (CESSDA). Also involved in SERISS are non-ESFRI research infrastructures: GGP - Generations and Gender Programme; EVS - European Values Survey and the WageIndicator Survey. ", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["INFRADEV-4-2014-2015 - Implementation and operation of cross-cutting services and solutions for clusters of ESFRI and other relevant research infrastructure initiatives"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-07-01"], "Project_ID": ["654221"], "Call_for_Proposal": ["H2020-INFRADEV-1-2014-1"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM", "UNIVERSITEIT VAN AMSTERDAM", "CENTRAAL BUREAU VOOR DE STATISTIEK"], "EU_Contribution": ["EUR 2 499 533"], "Project_Title": ["Intergenerational Reproduction and Solidarity in an Era of Family Complexity"], "Total_Cost": ["EUR 2 499 533"], "Country": ["Netherlands", "Netherlands", "Netherlands"], "Project_ACR": ["FamilyComplexity"], "Technology_Description": "One of the important consequences of the Second Demographic Transition has been the increasing complexity of families. The aim of this project is to study how rising family complexity has affected two fundamental aspects of intergenerational relationships: reproduction and solidarity. Theoretically, family complexity is distinguished into four dimensions: (a) the length, timing and nature of exposure to the child, (c) biological relatedness to the child, and (c) characteristics of parent-parent ties (triadic effects), (d) characteristics of the wider family network. Using insights from several disciplines, I develop a common theoretical framework for understanding intergenerational reproduction and solidarity. To test the theory, an innovative multiactor survey is developed with an oversampling strategy in which for each adult child, information is collected on all parent figures, and for each parent, information on all adult children. In addition, register data are used to analyze one aspect of reproduction in a dynamic fashion (educational reproduction) and vignette data are used to analyze one aspect of solidarity in more depth (norms prescribing solidarity). By studying reproduction and solidarity as outcomes, I shift the traditional focus from examining how the SDT has affected individual well-being, to the question of how the SDT has affected relationships. In doing so, I analyze a new problem in demography and sociology and contribute to classic debates about population ageing and social inequality. Theoretically, the study of family complexity yields unique opportunities to test ideas about the nature of intergenerational relationships and will shed new light on the traditional dichotomy of social vis-\u00e0-vis biological bases of intergenerational relationships. Methodological innovation is made by developing solutions for well-known problems of multiactor data, thereby strengthening the theoretical relevance of survey data for the social sciences.", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2015-11-01"], "Project_ID": ["669334"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["UNIVERSIDAD CARLOS III DE MADRID", "UNIVERSIDAD DE ZARAGOZA", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "UNIVERSITEIT VAN AMSTERDAM", "AALTO-KORKEAKOULUSAATIO", "UNIVERSITAT DE VALENCIA"], "EU_Contribution": ["EUR 2 663 237,25"], "Project_Title": ["Bridging the gap: from Individual Behaviour to the Socio-tEchnical MaN"], "Total_Cost": ["EUR 2 663 237,75"], "Country": ["Spain", "Spain", "United Kingdom", "United Kingdom", "Netherlands", "Finland", "Spain"], "Project_ACR": ["IBSEN"], "Technology_Description": "Developing models of real-world societal scenarios and systems is a key topic in the research agenda of social sciences, but is hindered by the lack of controlled experimentation with large groups of people. IBSEN will provide a breakthrough by building a repertoire of human behaviour in large (1000+ persons) structured groups using controlled experiments. To that end, we will develop a novel setup for large groups of people that will provide an experimental protocol, the necessary software and analytical tools to allow us to deal with thousands of people at the same time. We will apply our setup to specific research questions, focusing on novel phenomenology that may arise in large systems as compared to typical smaller ones, to find the rules that govern human behaviour in those cases, including the influence of social context and individual identity on them. We will assess our approach by building a model of human interaction in groups based on the behavioural rules we have found. The project requires a high-degree of interdisciplinarity; accordingly, the team consists of physicists, economists, social psychologists, and computer scientists. On the other hand, this is a high-risk project, as the experimental design may prove unfeasible for really large systems and extracting meaningful data from the participants\u2019 actions may not be possible. Notwithstanding, encouraging results in some pilot studies run by partners underpin the scientific feasibility of the concept and approach. If successful, researchers will be able to build on our findings to develop a human behaviour simulator, a technology providing a basis for socio-economic simulations that would radically change many fields, from robotics to economics, with technological and societal impacts, including policy-making in socially pressing issues. We will thus lay the foundations to kick start a new way of doing social science for the problems arising in a technologically highly connected society.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-1-2014 - FET-Open research projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["662725"], "Call_for_Proposal": ["H2020-FETOPEN-2014-2015-RIA"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET", "UNIVERSITEIT VAN AMSTERDAM", "LEIBNIZ-INSTITUT FUR GEMUSE- UND ZIERPFLANZENBAU GROSSBEEREN/ERFURT EV", "AARHUS UNIVERSITET", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "INOQ GmbH", "UNIWERSYTET MIKOLAJA KOPERNIKA W TORUNIU", "AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH", "DLF SEEDS AS", "TECHNISCHE UNIVERSITAET GRAZ", "ABITEP GMBH", "ACIB GmbH"], "EU_Contribution": ["EUR 3 907 754,64"], "Project_Title": ["Boosting plant-Endophyte STability, compatibility and Performance Across ScaleS"], "Total_Cost": ["EUR 3 907 754,64"], "Country": ["Denmark", "Netherlands", "Germany", "Denmark", "Spain", "Germany", "Poland", "Austria", "Denmark", "Austria", "Germany", "Austria"], "Project_ACR": ["BestPass"], "Technology_Description": "We need to increase the crop yield while reducing pesticide and use of inorganic fertiliser to meet the challenges of world population growth and climate change. Plant endophytic microorganisms can improve plant yield and enhance plant tolerance to abiotic stress as well as to pathogens under experimental conditions, but these effects are often not sufficiently stable for practical application. How do we boost the stability and reliability of the positive effects of endophytes on plants? We need to understand the genetic basis of beneficial interactions between crops and endophytes and extent this basis exhibits phenotypic plasticity at all interaction levels from the cellular to the field environment. This requires increasing our knowledge of the molecular mechanisms underlying the effects of endophytes, including intra and inter-kingdom exchange and distribution of resources (nutrients), signalling and possibly regulation between and inside the partners, the mutual induced production of secondary metabolites and the environmental cues which influence crop-endophyte interactions. The genetic variation and its plasticity in host and microbe will be exploited in to establish crop breeding and inoculum production processes for boosting the establishment and stability of plant-microbe mutualisms to benefit crop development, stress tolerance, pathogen resistance and quality. In this project we will provide fundamental biological as well as practical knowledge about interactions between endophytes and plants. This improved understanding will pave the way for increased use of endophytes to improve sustainability and plant productivity in a reliable way. The participants in this project comprise many of the key institutions and industries working with these problems and provide a uniquely strong consortium to address the key issues. Furthermore, the consortium will train a new generation of scientists who have the insight and skills to continue this task in their careers.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations"], "From": ["2015-09-01"], "Project_ID": ["676480"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["STAB VIDA INVESTIGACAO E SERVICOS EM CIENCIAS BIOLOGICAS LDA", "UNIVERSITY OF HULL", "GENOLOGICA MEDICA SL", "INSTITUT ZA ONKOLOGIJU I RADIOLOGIJU SRBIJE", "GENETIKS SAGLIK HIZMETLERI TICARETLIMITED SIRKETI", "UNIWERSYTET JAGIELLONSKI", "FUNDACAO DA FACULDADE DE CIENCIAS DA UNIVERSIDADE DE LISBOA FP", "FCIENCIAS.ID - ASSOCIACAO PARA A INVESTIGACAO E DESENVOLVIMENTO DE CIENCIAS", "UNIVERSIDAD SAN MARTIN DE PORRES ASOCIACION", "Institut Pasteur Du Maroc", "UNIVERSITE HASSAN II DE CASABLANCA", "PARSEQ LAB CO LTD", "FEDERAL UNIVERSITY OF AGRICULTURE ABEOKUTA", "RESPUBLIKA ONKOLOGIYA ILMIY MARKAZI", "UNIVERSITY OF TECHNOLOGY SYDNEY", "Sloan-Kettering Institute for Cancer Research CORPORATION", "MILLI ONKOLOGIYA MERKEZI"], "EU_Contribution": ["EUR 976 500"], "Project_Title": ["Blood test for clinical therapy guidance of non-small cell lung cancer patients"], "Total_Cost": ["EUR 1 039 500"], "Country": ["Portugal", "United Kingdom", "Spain", "Serbia", "Turkey", "Poland", "Portugal", "Portugal", "Peru", "Morocco", "Morocco", "Russia", "Nigeria", "Uzbekistan", "Australia", "United States", "Azerbaijan"], "Project_ACR": ["LungCARD"], "Technology_Description": "Lung cancer is the most common cancer worldwide. NSCLC alone make up about 75% of all lung cancers and most hospitals currently test all NSCLC patients for EGFR mutations (pharmacogenomics) for treatment decision (personalised medicine) \u2013 i.e., patients with mutation(s) in EGFR gene should receive a EGFR-Tyrosine Kinase Inhibitor (TKI) drug (e.g. afitinib) treatment; while those that do not present mutations in such gene, should be treated with chemotherapy. Currently, the laboratories use PCR and Sanger sequencing technologies to perform the EGFR analysis from tumour biopsies - Fixed Paraffin Embedded (FFPE) samples. Still, some patients (e.g., 30% in UK) may never get histological confirmation because they are too sick to make a biopsy. Furthermore, the results obtained with current methods still present low quality, mainly due to poor quality/low yield of DNA extracted from FFPE samples. The FP7 LungCARD project (www.lungcard.eu) has developed and demonstrated a LungCARD system - an automatic system composed by microfluidic chip and chip analyser - that allows to capture circulating tumour cells (CTCs) from blood samples, amplify by multiplex PCR and detect EGFR mutations, including also a software for data analysis and report. Although this new blood test has proven to be faster, cost-effective and human error-free, the detection of somatic mutations in EGFR gene at frequencies lower than 20% is still a weak point. ", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Portugal"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations"], "From": ["2017-01-01"], "Project_ID": ["734790"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["CENTRO DE NEUROCIENCIAS E BIOLOGIACELULAR ASSOCIACAO", "CONSIGLIO NAZIONALE DELLE RICERCHE", "Faculdade de Farm\u00e1cia da Universidade de Lisboa", "HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "UNIVERSITA DEGLI STUDI DI BARI ALDO MORO", "UNIVERSIDADE DO PORTO", "INSTYTUT BIOLOGII DOSWIADCZALNEJ IM. M. NENCKIEGO POLSKIEJ AKADEMII NAUK", "KING'S COLLEGE LONDON", "MEDIAGNOST GESELLSCHAFT FUR FORSCHUNG UND HERSTELLUNG VON DIAGNOSTIKA GMBH", "ASSOCIACAO PROTECTORA DOS DIABETICOS DE PORTUGAL", "OROBOROS INSTRUMENTS GmbH", "MICRO-BIOLYTICS GMBH"], "EU_Contribution": ["EUR 454 500"], "Project_Title": ["mitoFOIE GRAS: Non-invasive Profiling of Mitochondrial Function in Non-Alcoholic Fatty Liver Disease"], "Total_Cost": ["EUR 454 500"], "Country": ["Portugal", "Italy", "Portugal", "Germany", "Spain", "Italy", "Portugal", "Poland", "United Kingdom", "Germany", "Portugal", "Austria", "Germany"], "Project_ACR": ["mtFOIE GRAS"], "Technology_Description": "\"Non-Alcoholic Fatty Liver Disease (NAFLD), including its more pathologic consequence, non-alcoholic steatohepatitis (NASH), is believed to be the most common chronic liver disease worldwide, affecting between 6 to 37% of the population. NAFLD is a so called \u2018silent killer\u2019, as clinical symptoms only surface at late stages of the disease, when it is no longer treatable: untreated, NAFLD/NASH can lead to cirrhosis and hepatocellular carcinoma, culminating in liver failure. Currently the best method of diagnosing and staging the disease is liver biopsy, a costly, invasive and somewhat risky procedure, not to mention unfit for routine assessment. Besides, no therapeutic consensus exists for NAFLD/NASH treatment.", "To": ["2021-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Portugal"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-06-01"], "Project_ID": ["734719"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["HELMHOLTZ ZENTRUM POTSDAM DEUTSCHESGEOFORSCHUNGSZENTRUM GFZ", "FUTUREWATER BV", "ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA", "TECHNISCHE UNIVERSITAET WIEN", "GECOSISTEMA SRL", "STICHTING DELTARES", "UNIVERSITY OF BRISTOL", "MIDDLESEX UNIVERSITY HIGHER EDUCATION CORPORATION", "UMWELTBUNDESAMT", "HR WALLINGFORD LIMITED"], "EU_Contribution": ["EUR 3 884 131,08"], "Project_Title": ["A Large-Scale Systems Approach to Flood Risk Assessment and Management"], "Total_Cost": ["EUR 3 884 131,08"], "Country": ["Germany", "Netherlands", "Italy", "Austria", "Italy", "Netherlands", "United Kingdom", "United Kingdom", "Germany", "United Kingdom"], "Project_ACR": ["SYSTEM-RISK"], "Technology_Description": "Flood risk systems are characterised by physical and socio-economic processes acting at different space-time scales, by non-stationary and non-linear behaviour, and by a significant degree of interdependence between processes. This may lead to surprising developments and unanticipated side effects of risk reduction measures. A novel systems approach is needed that captures this dynamics and accounts for the interactions of the system components. We propose the ETN SYSTEM-RISK which aims at developing this systems approach for large spatial scales, from large river basins to the European scale. The research concept of SYSTEM-RISK builds upon the entire risk chain, from the source of hazard to consequences, and analyses the interactions and temporal dynamics in flood risk systems. In this way, the linear risk chain is replaced by a more realistic approach with interdependent links. SYSTEM-RISK exposes early-stage researchers (ESR) to all knowledge domains along the risk chain, and gives them, at the same time, the opportunity to build specific research profiles. The interdisciplinary setting and the focus on interactions and spatio-temporal dynamics of risk system will expand the mental models and lead to a new generation of creative scientists, able to transfer their systems perspective from flood risk systems to other fields. We bring together internationally leading groups in flood research with institutions from the non-academic main sectors exploiting flood research \u2013 consultancy, insurance industry and governmental sector. Close interaction will support the ESRs in developing trans-disciplinary skills with an understanding of both fundamental science and application. SYSTEM-RISK will deliver a suite of methods and tools for assessing and managing flood risk across large regions. This will be of highest importance for the EU Flood Directive and Strategy on Adaptation for Climate Change due to the EU\u2019s key role in dealing with risks transcending national borders.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations"], "From": ["2016-01-01"], "Project_ID": ["676027"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["FUNDACIO INSTITUT CATALA DE NANOCIENCIA I NANOTECNOLOGIA", "CONSIGLIO NAZIONALE DELLE RICERCHE", "Teknologian tutkimuskeskus VTT Oy", "UNIVERSITAT POLITECNICA DE VALENCIA", "UNIVERSITE DES SCIENCES ET TECHNOLOGIES DE LILLE - LILLE I", "UNIVERSITA POLITECNICA DELLE MARCHE", "MENAPIC SAS"], "EU_Contribution": ["EUR 2 915 885,75"], "Project_Title": ["All-Phononic circuits Enabled by Opto-mechanics"], "Total_Cost": ["EUR 2 915 886,25"], "Country": ["Spain", "Italy", "Finland", "Spain", "France", "Italy", "France"], "Project_ACR": ["PHENOMEN"], "Technology_Description": "This project is at the intersection of photonics, RF signal processing and phononics, aiming to achieve an all-optical phononic circuit using coherent phonons as the state variable. The concept is based on cavity optomechanics (OM) to develop GHz- frequency in-chip phononic circuits for room temperature operation. The circuits will integrate OM-pumped phonon sources and detectors as well as phonon processing components (waveguides, splitters, memories, photonic RF signal processing) to process information with phonons outside the cavity. The project seeks to prove two concepts. One is the efficient generation of GHz to tens of GHz coherent phonons, coupling them efficiently into a waveguide, engineering their propagation with low losses and detecting them at room temperature. The other is the synchronisation of two or more self-sustained OM cavities, which relies on the integration of several phononic components. Phonon-based processing will enable on-chip synchronisation and transfer of information carried between optical channels by phonons, which could eventually serve as a future scalable platform for, e.g., practical information processing with phonons. The technical work is organised in three work-packages: Theory, Components and Integration. The consortium is made up by three leading research institutes, three universities with an internationally recognised track-record in their respective areas of expertise and an industrial partner bringing their photonics, phononics, optomechanics, electrical engineering, integration, nanofabrication, theory, multi-physics/multi-scale modelling, instrumentation and application of detectors to the project.", "To": ["2019-08-31, ongoing project |"], "Meta": [""], "Topic_s": ["FETOPEN-1-2014 - FET-Open research projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-09-01"], "Project_ID": ["713450"], "Call_for_Proposal": ["H2020-FETOPEN-2014-2015-RIA"]}, -{"Partners": ["ECOLE CENTRALE DE LYON", "UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II.", "KATHOLIEKE UNIVERSITEIT LEUVEN", "UNIVERSITY OF BRISTOL", "UNIVERSITE DE FRANCHE-COMTE"], "EU_Contribution": ["EUR 3 131 359,47"], "Project_Title": ["VIbro-acoustics of PERiodic media"], "Total_Cost": ["EUR 3 131 359,47"], "Country": ["France", "Italy", "Belgium", "United Kingdom", "France"], "Project_ACR": ["VIPER"], "Technology_Description": "VIPER is a European Joint Doctorate network focused on research in VIbroacoustic of PERiodic media. Structural periodic", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-EJD - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-EJD)"], "Funding_scheme": ["MSCA-ITN-EJD - European Joint Doctorates"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["675441"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["TECHNISCHE UNIVERSITEIT EINDHOVEN", "TECHNISCHE UNIVERSITAET GRAZ", "TECHNISCHE UNIVERSITEIT DELFT", "UNIVERSITAET BIELEFELD", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "UNIVERSITY OF HULL", "MICROINNOVA ENGINEERING GMBH"], "EU_Contribution": ["EUR 3 896 827,50"], "Project_Title": ["Catalyst Cascade Reactions in \u2018One-Flow\u2019 within a Compartmentalized, Green-Solvent \u2018Digital Synthesis Machinery\u2019 \u2013 End-to-End Green Process Design for Pharmaceuticals"], "Total_Cost": ["EUR 3 896 827,50"], "Country": ["Netherlands", "Austria", "Netherlands", "Germany", "France", "United Kingdom", "United Kingdom", "Austria"], "Project_ACR": ["One-Flow"], "Technology_Description": "\"ONE-FLOW translates \u2018vertical hierarchy\u2019 of chemical multistep synthesis with its complex machinery into self-organising \u2018horizontal hierarchy\u2019 of a compartmentalized flow reactor system \u2013 a biomimetic digital flow cascade machinery with just one reactor passage. To keep horizontal hierarchy manageable, orthogonality among the consecutive reactions needs to be increased. The winning point of nature is to have invented catalytic cascades. ONE-FLOW will uplift that by enabling the best bio- and chemocatalysts working hand in hand. 4 synthetic flow cascades ('metabolic pathways\u2019) and 1 flow cascade driven by automated intelligence ('signaling pathway') will produce 4 Top-list 2020 drugs. \u2018The Compartmentalized Smart Factory\u2019 will develop organic, inorganic, and mechanical compartmentalization. \u2018The Green-Solvent Spaciant Factory\u2019 will fluidically allow the use of interim reaction spaces (spaciants). \u2018The Systemic Operations Factory\u2019 will aim at full orthogonality using data-base guided ultimate process harmonization. \u2018The Digital Machine-to-Machine Factory\u2019 will alter the landscape of chemical synthesis by virtue of the \"\"Internet of Chemical Things\"\". Automated machine-to-machine data transfer enables relegation of process monitoring to central computer systems under the oversight of chemists. \u2018The Fully Continuous Integrated Factory\u2019 will develop a commercial platform technology under the auspices of sustainability-driven process-design evaluation, making amenable the new kind of processing to all chemists. ONE-FLOW has massive impact potential: i) 38 billion Euro production cost saving; ii) 300 million EUR cost saving per drug; iii) address diseases with 500 billion Euro medication costs; iv) increase market share of emerging high-tech SME players by 10% in 10 years; v) open new windows of opportunity (personalized medicine) with 200-500 million Euro per disease; and vi) achieve 40% female share on a senior scientist level (ONE-FLOW: 34% senior, 57% junior).\"", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-01-2016-2017 - FET-Open research and innovation actions"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["737266"], "Call_for_Proposal": ["H2020-FETOPEN-1-2016-2017"]}, -{"Partners": ["STIFTUNG DEUTSCHES ELEKTRONEN-SYNCHROTRON DESY", "ISTITUTO NAZIONALE DI FISICA NUCLEARE", "CONSIGLIO NAZIONALE DELLE RICERCHE", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSITY OF STRATHCLYDE", "ASSOCIACAO DO INSTITUTO SUPERIOR TECNICO PARA A INVESTIGACAO E DESENVOLVIMENTO", "SCIENCE AND TECHNOLOGY FACILITIES COUNCIL", "Soci\u00e9t\u00e9 civile SYNCHROTRON SOLEIL", "THE UNIVERSITY OF MANCHESTER", "THE UNIVERSITY OF LIVERPOOL", "AGENZIA NAZIONALE PER LE NUOVE TECNOLOGIE, L'ENERGIA E LO SVILUPPO ECONOMICO SOSTENIBILE", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA", "UNIVERSITAET HAMBURG", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 2 999 900"], "Project_Title": ["Proposal for a Horizon 2020 Design Study on the \u201cEuropean Plasma Research Accelerator with eXcellence In Applications\u201c (EuPRAXIA)"], "Total_Cost": ["EUR 2 999 900"], "Country": ["Germany", "Italy", "Italy", "France", "United Kingdom", "Portugal", "United Kingdom", "France", "United Kingdom", "United Kingdom", "Italy", "France", "Italy", "Germany", "United Kingdom", "United Kingdom"], "Project_ACR": ["EuPRAXIA"], "Technology_Description": "EuPRAXIA will produce a conceptual design report for the worldwide first 5 GeV plasma-based accelerator with industrial beam quality and user areas. EuPRAXIA is the required intermediate step between proof-of-principle experiments and ground-breaking, ultra-compact accelerators for science, industry, medicine or the energy frontier (\u201cplasma linear collider\u201d). The study will design accelerator technology, laser systems and feedbacks for improving the quality of plasma-accelerated beams. Two user areas will be developed for a novel Free Electron Laser and High Energy Physics detector science. An implementation model will be proposed, including a comparative study of possible sites in Europe, a cost estimate and a model for distributed construction and installation at one central site. EuPRAXIA will be a new large research infrastructure with an estimated footprint of about 250 m. If the design study is approved, then it will lay the foundation for a possible decision on construction in 2020. ", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["INFRADEV-1-2014 - Design studies"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-11-01"], "Project_ID": ["653782"], "Call_for_Proposal": ["H2020-INFRADEV-1-2014-1"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON", "UNIVERSITEIT VAN AMSTERDAM", "THE UNIVERSITY OF EDINBURGH", "BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION", "SURFSARA BV", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "UNIVERSITE DE GENEVE", "THE UNIVERSITY OF SHEFFIELD", "CBK SCI CON LIMITED", "UNIVERSIDAD POMPEU FABRA", "LIFETEC GROUP BV", "ACELLERA LABS SL", "EVOTEC AG*", "BULL SAS", "Janssen Pharmaceutica NV"], "EU_Contribution": ["EUR 4 938 215,75"], "Project_Title": ["A Centre of Excellence in Computational Biomedicine"], "Total_Cost": ["EUR 4 938 216,25"], "Country": ["United Kingdom", "Netherlands", "United Kingdom", "Spain", "Netherlands", "United Kingdom", "Switzerland", "United Kingdom", "United Kingdom", "Spain", "Netherlands", "Spain", "Germany", "France", "Belgium"], "Project_ACR": ["CompBioMed"], "Technology_Description": "This Centre of Excellence will advance the role of computationally based modelling and simulation within biomedicine. Three related user communities lie at the heart of the CoE: academic, industrial and clinical researchers who all wish to build, develop and extend such capabilities in line with the increasing power of high performance computers. Three distinct exemplar research areas will be pursued: cardiovascular, molecularly-based and neuro-musculoskeletal medicine.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["EINFRA-5-2015 - Centres of Excellence for computing applications"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-10-01"], "Project_ID": ["675451"], "Call_for_Proposal": ["H2020-EINFRA-2015-1"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["'Feeling European'. The Visual Construction of EU Identity."], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["EVI"], "Technology_Description": "European Visual Identity - Summary", "To": ["2017-07-31, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-08-01"], "Project_ID": ["660793"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM", "UNIVERSITY COLLEGE LONDON", "INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK", "BAYERISCHE AKADEMIE DER WISSENSCHAFTEN", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "UNIVERSITEIT LEIDEN", "SCIENCE AND TECHNOLOGY FACILITIES COUNCIL", "ALLINEA SOFTWARE LIMITED", "CBK SCI CON LIMITED", "SAINT PETERSBURG NATIONAL RESEARCH UNIVERSITY OF INFORMATION TECHNOLOGIES, MECHANICS AND OPTICS", "BRUNEL UNIVERSITY LONDON"], "EU_Contribution": ["EUR 3 942 885"], "Project_Title": ["Computing Patterns for High Performance Multiscale Computing"], "Total_Cost": ["EUR 4 122 864,36"], "Country": ["Netherlands", "United Kingdom", "Poland", "Germany", "Germany", "Netherlands", "United Kingdom", "United Kingdom", "United Kingdom", "Russia", "United Kingdom"], "Project_ACR": ["ComPat"], "Technology_Description": "Multiscale phenomena are ubiquitous and they are the key to understanding the complexity of our world. Despite the significant progress achieved through computer simulations over the last decades, we are still limited in our capability to accurately and reliably simulate hierarchies of interacting multiscale physical processes that span a wide range of time and length scales, thus quickly reaching the limits of contemporary high performance computing at the tera- and petascale. Exascale supercomputers promise to lift this limitation, and in this project we will develop multiscale computing algorithms capable of producing high-fidelity scientific results and scalable to exascale computing systems. Our main objective is to develop generic and reusable High Performance Multiscale Computing algorithms that will address the exascale challenges posed by heterogeneous architectures and will enable us to run multiscale applications with extreme data requirements while achieving scalability, robustness, resiliency, and energy efficiency. Our approach is based on generic multiscale computing patterns that allow us to implement customized algorithms to optimise load balancing, data handling, fault tolerance and energy consumption under generic exascale application scenarios. We will realise an experimental execution environment on our pan-European facility, which will be used to measure performance characteristics and develop models that can provide reliable performance predictions for emerging and future exascale architectures. The viability of our approach will be demonstrated by implementing nine grand challenge applications which are exascale-ready and pave the road to unprecedented scientific discoveries. Our ambition is to establish new standards for multiscale computing at exascale, and provision a robust and reliable software technology stack that empowers multiscale modellers to transform computer simulations into predictive science.", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["FETHPC-1-2014 - HPC Core Technologies, Programming Environments and Algorithms for Extreme Parallelism and Extreme Data Applications"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["671564"], "Call_for_Proposal": ["H2020-FETHPC-2014"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["Effectiveness evaluation of traditional and third wave Emotion Regulation strategies in clinical and non-clinical youth population"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["PEACEFUL MIND"], "Technology_Description": "Mental-Health problems in youth such as disruptive behavioural disorders, substances abuse, aggressive behaviors, depression, anxiety, etc. is an expanding and global concern. Numerous Mental-Health problems in youth are significantly related with poor capacity of Emotion Regulation (ER). Adaptive ER strategies influence the intensity, duration, and expression of emotions, modifying emotional reactions in a socially tolerable and sufficiently flexible way. Thus, learning adaptive ER strategies has strong potential in promoting physical and psychological well-being in youth. However, the promise of an easy access and implementation of ER programs remains disappointedly unrealised for the following reasons. (1) Learning of ER competencies is almost invisible in European school curricula. (2) There is a lack of studies in youth that compare ER strategies to provide sufficient evidence-based criteria and guidelines. (3) The needs of the digital natives\u2019 generation have not been taken into consideration in ER programs, often lacking the engaging and motivational aspects and a high quality assessment. (4) There is an issue of adaptability of ER interventions to the school context. Thus, the main objective of PEACEFUL MIND is to develop an attractive program, using Information and Communication Technologies, as well as ecological and objective measures, to teach youths adaptive ER strategies. By doing so, we will directly influence social, emotional, and cognitive development of youths that will have an impact during their entire lives. Finally, the multidisciplinary training objective will provide an extensive clinical training in third wave therapies, training in research methodology, gaining experience in teaching, tutoring, and additional research competencies, which will open up the opportunity to become an expert in both the academic and private sectors, and will greatly contribute to my objective of becoming a scientific leader in third wave therapies and e-health.", "To": ["2018-09-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-04-01"], "Project_ID": ["656333"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITE PARIS 13"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Collective personalities: from individuals to groups, and back"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["GROUPIND"], "Technology_Description": "Many organisms, including humans, group together and perform collective actions such as birds forming coordinated flocks to evade predators, forage or roost. Some, as social insects, have evolved complex societies in which the unit of selection is not the individual, as in most vertebrates, but the colony. Yet, in both there is evidence of consistent behavioural variability among both individuals and groups. The study of collective behaviour - coordinated actions resulting in emergent properties at the group level - and the study of animal personality - between individual differences that are consistent over time and contexts - have progressed tremendously in the last two decades and are converging in their search for the link between individuality and collectivity, a fundamental and timely issue in biology. The GROUPIND project aims to investigate the relationship between individual personality and group personality by using ants and starlings as study organisms, both of which showing distinct collective behaviour and marked individual behavioural variability. The project will use a comparative approach to address the following objectives: (1) To characterize, also upon experimental manipulation, the composition of personalities in the group and understand how this relates to personality at the group level. Are group personalities an average of individual personalities within the group? Do they result from different distributions of individual personalities? Are there keystone individuals that exert a disproportionate influence on the group personality? (2) To understand how diversity of individual personalities contributes to decision making and to the ecological success at the group level, and how this would feed back at the individual level. By bridging two major fields of study, this project will shed new light on the ability of groups to function effectively, unravelling the consequences that personality differences can exert on social life and its evolution.", "To": ["2017-09-30, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["659106"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITEIT MAASTRICHT", "UNIVERSITEIT VAN AMSTERDAM", "UNIVERSITY OF GLASGOW", "THE BOARD OF TRUSTEES OF THE TATE GALLERY", "UNIVERSIDADE NOVA DE LISBOA", "TECHNISCHE HOCHSCHULE KOLN", "UNIVERSITA DEGLI STUDI ROMA TRE", "AKADEMIA SZTUK PIEKNYCH W WARSZAWIE", "UNIVERSIDADE DO PORTO", "COMUNE DI MILANO"], "EU_Contribution": ["EUR 3 812 140,80"], "Project_Title": ["New Approaches in the Conservation of Contemporary Art"], "Total_Cost": ["EUR 3 812 140,80"], "Country": ["Netherlands", "Netherlands", "United Kingdom", "United Kingdom", "Portugal", "Germany", "Italy", "Poland", "Portugal", "Italy"], "Project_ACR": ["NACCA"], "Technology_Description": "The importance of European cultural heritage has been generally acknowledged. A significant part of this heritage, however, modern and contemporary art, runs a great risk of getting lost for future generations, because it is particularly difficult to preserve. Proper care requires resolving fundamental questions concerning the identity and authenticity of modern and contemporary artworks and the consequences for their conservation, rethinking historically grown professional distinctions as those between the curator and the conservator, re-organizing the institutional ecosystem, and establishing frameworks for international, interdisciplinary and intersectoral research and training collaboration. The aim of this Marie Curie Innovative Training Network is to educate a new generation of professional curators, conservators and academic researchers who are properly equipped to face these challenges. The key notion guiding the research and training programmes will be the notion of reflective practice. Starting from the theoretical framework of practice theory, the research programme will investigate conservation practices through the comparative analysis of their impact on modern and contemporary artworks\u2019 biographies. The training programme will focus on the development of a reflective professional attitude, which is a pre-requisite in this increasingly complex and collaborative field.", "To": ["2019-05-31, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2015-06-01"], "Project_ID": ["642892"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM", "CARDIFF UNIVERSITY", "MAAT France", "CONSIGLIO NAZIONALE DELLE RICERCHE", "UNIVERSIDAD DE ALCALA", "MARTIN-LUTHER-UNIVERSITAET HALLE-WITTENBERG"], "EU_Contribution": ["EUR 1 005 875"], "Project_Title": ["GLOBal Infrastructures for Supporting Biodiversity research"], "Total_Cost": ["EUR 1 005 875"], "Country": ["Netherlands", "United Kingdom", "France", "Italy", "Spain", "Germany"], "Project_ACR": ["GLOBIS-B"], "Technology_Description": "Biodiversity and ecosystem research is addressing the grand societal challenge to predict the biosphere under global environmental change. To advance scientific progress in understanding the complexity of natural systems it is required that supporting research infrastructures cooperate globally to serve the essential data at different temporal and spatial scales. This includes providing the capabilities to process big and massive datasets. GLOBIS-B is a global cooperation of world-class research infrastructures with a focus on targeted services to support frontier research that deals with predicting the biosphere and measuring the indicators of biodiversity change. The project brings key scientists together with global research infrastructure operators and legal interoperability experts to address research needs and infrastructure services underpinning the concept of Essential Biodiversity Variables (EBVs). EBVs were proposed by the GEO Biodiversity Observation Network (GEO BON) and are a prerequisite for understanding biodiversity and ecosystem change. Integrated scientific and technical workshops will identify the required primary data, analysis tools, methodologies etc. to develop an infrastructure development agenda for computing EBVs and to explore the discovery of required and interoperable data at larger spatial and temporal scales. Applications of common standards and workflows that are \u2018self-documenting\u2019 and openly shared facilitate international cooperation, and realistic and pragmatic solutions are explored to streamline the legal bottlenecks for the reciprocal use of data and software tools from different origins. Solutions should be workable for both the scientific communities and the cooperating research infrastructures, especially in regard to achieving direct machine-machine interactions. The interaction with national, supra-national and global policy bodies contributes to potential refinements of general policies supporting legal interoperability.", "To": ["2018-05-31, ongoing project"], "Meta": [""], "Topic_s": ["INFRASUPP-6-2014 - International cooperation for research infrastructures"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-06-01"], "Project_ID": ["654003"], "Call_for_Proposal": ["H2020-INFRASUPP-2014-2"]}, -{"Partners": ["UNIVERSITY OF BATH", "RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN", "FONDAZIONE BRUNO KESSLER", "UNIVERSITA DEGLI STUDI DI GENOVA", "MAPLESOFT EUROPE LIMITED", "UNIVERSITE DE LORRAINE", "COVENTRY UNIVERSITY", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "UNIVERSITAET KASSEL", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "UNIVERSITAT LINZ"], "EU_Contribution": ["EUR 499 603,75"], "Project_Title": ["SC-square - Satisfiability Checking and Symbolic Computation: uniting two communities to solve real problems"], "Total_Cost": ["EUR 499 603,75"], "Country": ["United Kingdom", "Germany", "Italy", "Italy", "United Kingdom", "France", "United Kingdom", "United Kingdom", "Germany", "Germany", "Austria"], "Project_ACR": ["SC-square"], "Technology_Description": "The use of advanced methods to solve practical and industrially relevant problems by computers has a long history. Whereas Symbolic Computation is concerned with the algorithmic determination of exact solutions to complex mathematical problems, more recent developments in the area of Satisfiability Checking tackle similar problems but with different algorithmic and technological solutions. ", "To": ["2018-08-31, ongoing project |"], "Meta": [""], "Topic_s": ["FETOPEN-3-2015 - Coordination and Support Activities"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Higher or Secondary Education Establishments"], "From": ["2016-07-01"], "Project_ID": ["712689"], "Call_for_Proposal": ["H2020-FETOPEN-2015-CSA"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM", "UNIVERSITETET I STAVANGER", "UNIVERSITY OF SOUTHAMPTON", "FTK FORSCHUNGSINSTITUT FUR TELEKOMMUNIKATION UND KOOPERATION EV", "STICHTING EGI", "ENGINEERING - INGEGNERIA INFORMATICA SPA", "INMARK ESTUDIOS Y ESTRATEGIAS SA", "INMARK EUROPA SA"], "EU_Contribution": ["EUR 2 500 000"], "Project_Title": ["Education for Data Intensive Science to Open New science frontiers"], "Total_Cost": ["EUR 2 500 000"], "Country": ["Netherlands", "Norway", "United Kingdom", "Germany", "Netherlands", "Italy", "Spain", "Spain"], "Project_ACR": ["EDISON"], "Technology_Description": "The EDISON project will focus on activities to establish the new profession of ' Data Scientist', following the emergence of Data Science technologies (also referred to as Data Intensive or Big Data technologies) which changes the way research is done, how scientists think and how the research data are used and shared. This includes definition of the required skills, competences framework/profile, corresponding Body Of Knowledge and model curriculum. It wil develop a sustainability/business model to ensure a sustainable increase of Data Scientists, graduated from universities and trained by other professional education and training institutions in Europe. ", "To": ["2017-08-31, closed project |"], "Meta": [""], "Topic_s": ["INFRASUPP-4-2015 - New professions and skills for e-infrastructures"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-09-01"], "Project_ID": ["675419"], "Call_for_Proposal": ["H2020-INFRASUPP-2015-1"]}, -{"Partners": ["UNIVERSITY OF BRISTOL", "UNIVERSITY OF BRISTOL", "ISTANBUL TEKNIK UNIVERSITESI", "BATH SPA UNIVERSITY"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Beyond East and West: Developing and Documenting an Evolving Transcultural Musical Practice"], "Total_Cost": ["EUR 2 000 000"], "Country": ["United Kingdom", "United Kingdom", "Turkey", "United Kingdom"], "Project_ACR": ["Integrating Turkish"], "Technology_Description": "For composers in Turkey today, the urge to integrate the beauties of Turkey\u2019s rich musical heritage into contemporary concert music has become almost an imperative. But differences in tuning, texture, and between oral and notated orientations to performance have presented seemingly intractable obstacles. This project systematises practical processes essential for the creation of a new, East-West strand of contemporary music and opera. It initiates cutting-edge research workshops in Istanbul, Holland and the UK to: 1. Train top-level traditional instrumentalists and singers in Turkey effectively to perform a new repertoire; 2. Train top professional Western singers in non-Western techniques and nuances of vocal production; 3. Develop approaches for modelling such music's impacts on Turkish and Western musicians\u2019 adaptive processes in rehearsal and performance, and diverse audiences\u2019 perceptions of such music; 4. Create an ensemble interface (including newly designed instruments) to increase capacity for merging sounds beyond levels now achievable; 5. Produce groundbreaking studies on timbre to provide new insights into how sound is produced; 6. Establish a new template for mapping Eastern and Western tuning systems onto one another. This research, together with an orchestration manual for Turkish sounds will comprise the core of a published (CUP) team-authored e-book, Integrating Turkish Instruments and Voices into Contemporary Music (ITI), with included audio and visual examples linked as an online resource. Looking further, this project\u2019s multi-modal, transdisciplinary approach also suggests a model for probing how the \u2018free play\u2019 of the imagination (Kant) possible within processes of art and its creation can provide metaphors towards understanding one of the most urgent and compelling issues of our time: how to transcend cultural barriers (real or imagined) that exist today.", "To": ["2020-08-31, ongoing project |"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["648810"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["KING'S COLLEGE LONDON"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Structural and functional studies of LARP4, a new RNA binding protein involved in mRNA stabilisation and cell migration"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["LARP4MOT"], "Technology_Description": "RNA-binding proteins (RBPs) act at multiple levels to regulate gene expression, including mRNA splicing, polyadenylation, localisation, stability, decay and translational efficiency and, although central to health and disease, much of this precise concerted regulation remains to be uncovered. The recently discovered LARP4 is an RBP that affects mRNA stability and binds to polyA as well as the polyA-binding protein (PABP). Intriguingly, LARP4 has recently been identified as a regulator of cell morphology and migration in an RNAi screen, but little is known about how control of gene expression at the translational level is coordinated during cell migration and invasion. Since aberrant cell migration contributes to the development of human diseases including cancer, chronic inflammation and atherosclerosis, LARP4 represents an excellent RBP to advance our understanding of key cellular mechanisms relating to mRNA processing and turnover. ", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["655341"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["PIN SOC.CONS. A R.L. - SERVIZI DIDATTICI E SCIENTIFICI PER L UNIVERSITA DI FIRENZE", "INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE", "CLARIN ERIC", "KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW", "THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN", "CONSIGLIO NAZIONALE DELLE RICERCHE", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS", "KING'S COLLEGE LONDON", "OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN", "Istituto Centrale per il Catalogo Unico delle biblioteche italiane e per le informazioni bibliografiche", "GEORG-AUGUST-UNIVERSITAT GOTTINGENSTIFTUNG OFFENTLICHEN RECHTS", "SOCIETA INTERNAZIONALE PER LO STUDIO DEL MEDIOEVO LATINO-S.I.S.M.E.L.ASSOCIAZIONE", "ACADEMY OF ATHENS", "FACHHOCHSCHULE POTSDAM", "DIGITAL RESEARCH INFRASTRUCTURE FOR THE ARTS AND HUMANITIES"], "EU_Contribution": ["EUR 11 999 711"], "Project_Title": ["Pooling Activities, Resources and Tools for Heritage E-research Networking, Optimization and Synergies"], "Total_Cost": ["EUR 11 999 711"], "Country": ["Italy", "France", "Netherlands", "Netherlands", "Ireland", "Italy", "France", "Spain", "Greece", "United Kingdom", "Austria", "Italy", "Germany", "Italy", "Greece", "Germany", "France"], "Project_ACR": ["PARTHENOS"], "Technology_Description": "PARTHENOS aims at strengthening the cohesion of research in the broad sector of Linguistic Studies, Humanities, Cultural Heritage, History, Archaeology and related fields through a thematic cluster of European Research Infrastructures, integrating initiatives, e-infrastructures and other world-class infrastructures, and building bridges between different, although tightly, interrelated fields. PARTHENOS will achieve this objective through the definition and support of common standards, the coordination of joint activities, the harmonization of policy definition and implementation, and the development of pooled services and of shared solutions to the same problems.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["INFRADEV-4-2014-2015 - Implementation and operation of cross-cutting services and solutions for clusters of ESFRI and other relevant research infrastructure initiatives"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555", "Higher or Secondary Education Establishments", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2015-05-01"], "Project_ID": ["654119"], "Call_for_Proposal": ["H2020-INFRADEV-1-2014-1"]}, -{"Partners": ["UNIVERSITY OF PORTSMOUTH HIGHER EDUCATION CORPORATION"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Cosmology with voids and superclusters: combining theory, simulation and observation"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["COSMOVOID"], "Technology_Description": "The aim of this cosmology proposal is to study the contents, history and evolution of our Universe, using the distribution of matter on large scales. I propose to study new methods to identify and catalogue rare voids and superclusters in the large-scale structure of the Universe and to study their statistical, morphological and dynamical properties. I will use these studies to propose new observables and new techniques of data analysis based on these structures, and to use this knowledge to test theories of gravitation, dark energy and the initial conditions of the early Universe. Interest in cosmic voids in particular has increased greatly in recent years, as they have been suggested as extremely competitive probes of cosmology, according to some estimates significantly out-performing other methods. Yet there remain unsolved theoretical difficulties in the modelling of voids and even a lack of consensus on how to identify them and how to relate theory and observation. Even less is currently known about superclusters. These are among the important issues I propose to address. My proposal consists in roughly equal parts of: analysis of the latest high-quality survey data which will available from the Sloan Digital Sky Survey (SDSS) and the Dark Energy Survey (DES); analysis of the state-of-the-art Jubilee ISW and weak lensing simulations run on the Juropa supercomputer in Germany; and theoretical work to combine insights from data and simulation to improve our understanding of cosmology. The proposed work is to be carried out in collaboration with leading experts in the respective fields from across the European Community, in particular in the United Kingdom, Spain and Germany.", "To": ["2017-09-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["660053"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["LOCAL OWNERSHIP IN SECURITY SECTOR REFORM ACTIVITIES WITHIN CSDP OPERATIONS OF THE EU"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["EU and SSR"], "Technology_Description": "Between 2002 and 2014, the EU has deployed 30 civilian and military operations in Europe, Africa and Asia, under its Common Security and Defense Policy (CSDP). For most of these operations, the EU has a mandate to do activities related to the Security Sector Reform (SSR), aimed at the provision of national and human security within a framework of democratic governance. One of the core assumptions underpinning the EU\u2019s operations has been that SSR has to be \u201clocally owned\u201d in order to be successful, meaning that local agents should internalize principles and objectives of externally driven reforms. Local ownership, however, remains a neglected concept not only theoretically speaking, but it is also very difficult to be implemented in practice. The theoretical and policy gap informs three principal aims of this project. First, the project will adopt a fresh theoretical framework for the study of local ownership. Drawing on the work of Michel Foucault, the project will conceptualize local ownership as a technology of international security \u201cgovernmentality\u201d wherein external actors employ set of techniques with the aim of turning local agents into subjects responsible for externally-driven security sector reform agenda. Such an approach will situate local ownership of CSDP operations within a wider context of emerging liberal security governance and explain why it continuously face implementation difficulties in semi-liberal or illiberal settings. Second, the project will obtain new empirical insights into how local ownership is being practised on the ground within three ongoing CSDP operations (EULEX Kosovo, EUPOL COPPS and EUTM Mali) and into why these projects continue to face implementation problems. The third objective of the project is to develop a set of policy recommendations that will assist future policy planners in conceiving more reflexive, context-sensitive and cost-effective local ownership strategies to be applied in current or future CSDP operations.", "To": ["2017-10-06, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-10-07"], "Project_ID": ["656971"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["INSTITIUID TEICNEOLAIOCHTA BHAILE ATHA CLIATH"], "EU_Contribution": ["EUR 175 866"], "Project_Title": ["Automated Raman spectral Cytology for detection of human papillomavirus (HPV) infection and cervical pre-cancer"], "Total_Cost": ["EUR 175 866"], "Country": ["Ireland"], "Project_ACR": ["ARC-HPV"], "Technology_Description": "The Experienced Researcher (ER), Dr Shiyamala Duraipandian, who is at the centre of this application, will, through this MSCA Fellowship, enhance her research and innovation potential through advanced training, international and inter-sectoral mobility. The ER will develop methods for detecting high risk HPV infection and dysplasia using Raman spectroscopy in cervical cells collected during routine Pap smear screening. Her skills in instrument and software development and patient testing will complement the expertise of the host laboratory. During the project measurable knowledge transfer towards the ER will be facilitated through DIT\u2019s Postdoctoral Training Programme, RESC induction and specialist skills transfer, strengthened academic and industry network contacts, via existing networks and industry events, and preparation of a dedicated career development plan.", "To": ["2018-01-17, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-01-18"], "Project_ID": ["661398"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["STICHTING KATHOLIEKE UNIVERSITEIT", "STICHTING KARAKTER", "UNIVERSITY OF LEICESTER", "KING'S COLLEGE LONDON", "KAROLINSKA INSTITUTET", "UNIVERSITAT DE BARCELONA", "BRAINGAZE SL", "FUNDACIO HOSPITAL UNIVERSITARI VALL D'HEBRON - INSTITUT DE RECERCA", "EUROFINS MEDIGENOMIX GMBH", "JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN", "UNIVERSITAETSKLINIKUM WUERZBURG - KLINIKUM DER BAYERISCHEN JULIUS-MAXIMILIANS-UNIVERSITAT", "UNIVERSITETET I BERGEN", "FUNDACIO CENTRE DE REGULACIO GENOMICA"], "EU_Contribution": ["EUR 3 913 940,43"], "Project_Title": ["Mastering skills in the training Network for attention deficit hyperactivity and autism spectrum Disorders"], "Total_Cost": ["EUR 3 913 940,43"], "Country": ["Netherlands", "Netherlands", "United Kingdom", "United Kingdom", "Sweden", "Spain", "Spain", "Spain", "Germany", "Germany", "Germany", "Norway", "Spain"], "Project_ACR": ["MiND"], "Technology_Description": "Attention deficit/hyperactivity disorder (ADHD) and autism spectrum disorders (ASD) are frequent, chronic and highly heritable neurodevelopmental disorders. Despite their societal importance, progress in understanding disease biology has been slow and no curative treatment options are available.", "To": ["2018-12-31, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Other", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2015-01-01"], "Project_ID": ["643051"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["KING'S COLLEGE LONDON"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Investigating Natural, Historical, And Institutional Transformations - Cities"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["INHABIT Cities"], "Technology_Description": "The overall aim of INHAbIT is to improve understandings of the dynamics of water service provision in urban environments in the global South. In particular, INHAbIT will explore historical processes and transformations that have shaped water service configurations, the politics of socio-technical urban water supply systems and the socio-ecological processes shaping the urban waterscape. INHAbIT is innovative in that it takes an interdisciplinary approach and aims at developing new methodologies and conceptual approaches. To this aim, INHAbIT has identified three objectives, which combine theoretical, methodological and empirical elements: undertake a theoretical synthesis that brings urban political ecology perspectives into engagement with institutional bricolage; explore and test innovative methodologies for tracking informality and investigating socio-natural processes; undertake empirical work and building up a robust body of rigorously researched historical and qualitative data on natural, historical and institutional transformations that have shaped and continuously re-shape water service realities in Lilongwe (Malawi) and Maputo (Mozambique). While taking a critical approach, INHAbIT is also cognizant of the needs of policy makers and practitioners for solutions that work for serving with adequate water a growing population. The researcher, Maria Rusca, will explore the implications of INHAbIT\u2019s research findings for policy and practice and disseminate accordingly. INHAbIT, thus, will be both scientifically innovative and policy relevant.", "To": ["2017-09-13, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-14"], "Project_ID": ["656738"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["POLITECNICO DI TORINO", "UNIVERSITY OF BRISTOL", "ECOLE NATIONALE SUPERIEURE D'ARTS ET METIERS", "GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER", "LUXEMBOURG INSTITUTE OF SCIENCE AND TECHNOLOGY", "ELAN-AUSY GMBH"], "EU_Contribution": ["EUR 3 095 280,36"], "Project_Title": ["FULLY INTEGRATED ANALYSIS, DESIGN, MANUFACTURING AND HEALTH-MONITORING OF COMPOSITE STRUCTURES"], "Total_Cost": ["EUR 3 095 280,36"], "Country": ["Italy", "United Kingdom", "France", "Germany", "Luxembourg", "Germany"], "Project_ACR": ["FULLCOMP"], "Technology_Description": "Composite structures are massively exploited in many engineering fields. For instance, the state-of-the-art civil aircraft (B787 and A350) are mostly made of composite materials. The design of composites leads to challenging tasks since those competencies that stemmed from the adoption of metallic materials are often inadequate for composites. Insights on many different disciplines and tight academic/industrial cooperation are required to fully exploit composite structure capabilities. The skills and the employability of young researchers increase to a great extent through an interdisciplinary and intersectoral training. The existing training schemes are often based on specific themes and disciplines rather than on a broad interdisciplinary and academic-industrial integrated approach. The main aim and novelty of this project is the creation of a multidisciplinary, intersectoral and international research training network based on a strong academic basis and industrial partnerships for a new generation of top talented young researchers that will work in the European academic and industrial scenarios. The multidisciplinary features are guaranteed by the presence of 7 universities, 1 research centre and 1 industry. The intersectoral approach will be pursued by including secondments and specific industrial training requirements in each individual project. The consortium is composed by partners from 8 countries. OTC partners were included for secondment and training opportunities; they were chosen on the basis of their expertise and to enhance the internationality features of the training. Their presence is seen as an opportunity for the European partners and researchers to strengthen competencies. The full spectrum of the design of composite structures will be dealt with - manufacturing, health-monitoring, failure, modelling, multiscale approaches, testing, prognosis and prognostic - to develop integrated analysis tools to improve the design of composites.", "To": ["2019-05-31, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-06-01"], "Project_ID": ["642121"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["DEBRECENI EGYETEM"], "EU_Contribution": ["EUR 109 679,40"], "Project_Title": ["Knowledge, Skills and Attitudinal Competences for Quality Early childhood Education and Care"], "Total_Cost": ["EUR 109 679,40"], "Country": ["Hungary"], "Project_ACR": ["ECECWorkforce"], "Technology_Description": "The education and training of the Early Childhood Education and Care (ECEC) workforce is of prime importance as it equips practitioners with the knowledge, skills and attitudinal competences needed to work with children. Training supports them in creating quality environments for children to enhance the quality of provision and subsequent child outcomes. The research is timely with the increased interest in the benefits of quality ECEC for supporting the holistic development of children, but with a need to understand more about the role of the workforce in this. Whilst qualifications have been established as important for the quality of ECEC, little is known about the nature of the qualifications and the role that they play in developing the knowledge, skills and attitudinal competences needed to best enhance the quality of ECEC provision. The research will focus on ECEC qualification requirements, structure, content and characteristics across Europe. The project will analyse (via secondary data) the qualification requirements across Europe, the composition of the qualifications and their relationship to child outcomes. This macro level analysis will be supported by a detailed investigation (via empirical research) into the delivery of qualifications and the role they play in developing the knowledge, skills and attitudinal competences appropriate to the context. The detailed investigation of qualifications will consider the formulation, delivery, experiences and application of ECEC higher education training in the host\u2019s institution, selected for its expertise in training kindergarten pedagogues in Hungary. ECEC in Hungary is under explored, whilst also offering an interesting case to study due to how its history, market composition and quantity of provision contrast with those experienced by the Fellow in the UK. Pertinent for this research is emerging evidence on the divergent views of the knowledge, skills and attitudinal competences needed to work in ECEC.", "To": ["2017-02-28, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Hungary"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["657512"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Hierarchical surface patterns from dissolution-reaction-crystallisation mediated evaporation controlled self-assembly (DRC-ECA) and its antimicrobial coating application"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["DRC-ECSA"], "Technology_Description": "A preliminary study by the applicant (Dr. Hua Wu (HW)) has proposed a novel dissolution-reaction-crystallisation mediated evaporation controlled self-assembly (DRC-ECSA) mechanism, from surprising and unprecedented observations of complex residual surface patterns with hierarchical architecture self-assembled upon evaporative drying of a ZnO nanofluid droplet. This mechanism is very di\ufb00erent from that previously established for the co\ufb00ee ring e\ufb00ect and other ECSA processes, and the morphological and nanostructural details of the obtained surface patterns also depend intricately on \u2013 thus are tuneable by \u2013 a range of physical parameters. Much of the complexity due to these corroborating factors remains to be fully explored. The aim of the project is threefold: 1) to fully understand the DRC-ECSA mechanism by comprehensively investigating the effects of physical parameters such as the solvent mixtures, evaporation rate, ZnO nanofluid concentration, shape and size of ZnO particles, addition of surfactants and polymers, substrate chemistry, droplet volume, temperature and humidity; 2) to apply and extend the DRC-ECSA mechanism (e.g. in a confined geometry and using binary particle mixtures) to obtain sophisticated surface patterns with tailored morphologies and hierarchical structures; 3) to evaluate the efficacy of the surface patterns for potential applications in antimicrobial coatings. By leading and engaging in the proposed project, Dr. HW will acquire new skills and knowledge in a range of interdisciplinary and multidisciplinary scientific and technical areas, including non-equilibrium ECSA, nucleation and crystal growth, morphological and structural characterization, nanoparticle synthesis, and microbiology of nanostructured surfaces. A broad range of transferrable skills acquired through the enriching experience of this interdisciplinary project will be very beneficial to Dr. HW\u2019s longer term career plans to become an independent research leader.", "To": ["2017-09-03, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-04"], "Project_ID": ["656830"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Magnetic micromachines based on protocell design and engineering"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["MagProtoCell"], "Technology_Description": "Protocells are artificial cellular systems exhibiting lifelike properties, which are proposed as a stepping-stone for understanding the origin of life on Earth. Features such as encapsulation, replication, metabolism and selective exchange of chemicals with the environment will enable their use as micromachines in a number of emerging applications (e.g., environment clean-up, clinical diagnosis, drug delivery, remote sensing, bioreactor technology). However, progress in such applications will be enhanced by the synthetic construction of protocells capable of directed movement in fluidic environments in response to external stimuli. To date, motility has been achieved only in a few cases, which involve a response to changes in chemical concentrations (chemotaxis) in the surrounding medium. However, controlling the chemical composition of the local environment is challenging, and thus alternative ways to stimulate motility are needed. In this regard, external magnetic fields (MFs) will enable high levels of control of protocell motility and spatial disposition to be achieved by employing noncontact forces. This is the aim of this proposal: to design and construct synthetic protocells able to sense and respond to external MFs. A key outcome of the work will be the development of a new class of magnetic micromachines based on protocell design and engineering. Such machines will couple MF-directed motility with the temporal and spatial delivery of advanced biomimetic functions. The key factor of the proposed methodology is the inclusion of colloidal magnetic particles at strategic locations in the protocell composition or in the external medium. Thereby, the expertise of the applicant (Dr. Rodr\u00edguez Arco) in the field of MF-responsive materials will be applied to the multidisciplinary and cutting-edge field of protocells in which the hosting group at the University of Bristol (under the leadership of Prof. Mann FRS) has made great progress in the last few years.", "To": ["2017-04-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-05-01"], "Project_ID": ["656490"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITE PARIS 13"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Homotopy theory of cosimplicial unstable (co-)algebras over the Steenrod algebra"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["HotCoalgebras"], "Technology_Description": "This research proposal is in mathematics, its content is part of algebraic topology and homotopy theory. It aims at deepening our understanding of the homotopy theory of cosimplicial unstable (co-)algebras over the Steenrod algebra and its relation to the homotopy theory of cosimplicial spaces. This is achieved by new methods developed recently by the ER (Dr. Biedermann) and coauthors and by methods from Goodwillie calculus. Specifically, there are three closely related parts/work packages: ", "To": ["2017-04-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-05-01"], "Project_ID": ["661067"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Stereocontrolled synthesis of polypropionates based on building block assembly strategies by lithiation-borylation methodologies"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["BBLOCK"], "Technology_Description": "Amongst all natural products, polyketides constitute a very important class due to their broad spectrum of biological activities (eg. antibiotic, antitumoral, antifungal, antiparasitic). Many of these compounds are referred to as polypropionates, which are characterized by sequences of methyl- and hydroxy-bearing stereogenic centres, enabling large numbers of possible stereochemical permutations. The importance of these natural products as therapeutic agents and as biomedical tools together with their structural complexity has made these molecules attractive targets for synthetic organic chemistry. The key to construct these systems, which posses a high level of stereochemical information, is the control of the absolute and relative stereochemistry of each centre. Herein we propose the development of a novel and general strategy for the synthesis of any polypropionate-like molecule based on the construction of a building block assembly platform. This process will capitalize on the well-established lithiation-borylation methodology so complete control of both relative and absolute stereochemistry of all chiral centres will be achieved. The power of the strategy will be demonstrated in the synthesis of the polypropionate core of the antibiotic Streptovaricin U. The successful development of this research will shortcut the synthesis of stereochemically defined polypropionates combining building blocks of varying length. Moreover, the possibility to modify the stereochemistry of any centre will allow access to all known natural polypropionate fragments and will permit the preparation of non-natural analogues too. The development of such an ambitious and innovative project in the University of Bristol will be facilitated by generating, transferring, sharing and disseminating knowledge, and will enhance my career development following the training plan envisioned.", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["655682"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["Rearm cultivated tomato with natural and durable resistance mechanisms from wild tomato species"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["DURETO"], "Technology_Description": "Insects are gaining resistance to commercially available pesticides and effective insecticides (e.g. neonicotinoids) are currently being banned. Consequently, there is a real threat that the EU vegetable production will be affected. Wild tomato species have the ability to defend themselves by producing natural defence compounds that have a toxic or repellent effect on insects. These compounds are produced and stored in glandular hairs (trichomes) on the plant stem and leaf surface. Extensive breeding in protected environments led to the loss of these defence compounds in cultivated tomatoes. It was previously shown that the introduction of the terpene 7-epizingiberene biosynthetic pathway from a wild tomato in trichomes of cultivated tomato results in an enhanced resistance to insects. However, the regulatory factors that govern the production of these defence compounds seem also essential for successful incorporation of \u2018wild resistance\u2019 into breeding material. Here, I aim to discover metabolic defence mechanisms present in the trichomes of wild tomato species that can be re-introduced into cultivated tomato with a focus on post-transcriptional regulation of biosynthetic pathways. I will evaluate insect resistance in a collection of wild and cultivated tomato accessions and associate phenotypic and transcriptional data via a Systems Biology approach. I will also sequence small RNAs and compare them quantitatively with messenger RNAs to identify post-transcriptional regulations. Next, I will follow a comparative genomic approach by mapping the selected transcripts to their corresponding tomato genomes to associate polymorphisms and resistance phenotypes. These results will be directly translated into molecular markers that the industry can implement in breeding programmes. This proposal will help me become an independent researcher, combining my background in plant biology with knowledge on bioinformatics, biostatistics and state-of-the-art technology.", "To": ["2017-04-30, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-05-01"], "Project_ID": ["655656"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI TRENTO"], "EU_Contribution": ["EUR 180 277,20"], "Project_Title": ["The neural basis of visual interaction between scenes and objects"], "Total_Cost": ["EUR 180 277,20"], "Country": ["Italy"], "Project_ACR": ["SEEING FROM CONTEXT"], "Technology_Description": "We easily categorize places and objects in a single glance, a computationally complex task presenting a central challenge for vision neuroscience. Considerable evidence points to a division of scene and object processing into two distinct neural pathways, relying on different types of visual cues. However, scenes and objects are also known to strongly interact in visual perception, as seen in contextual effects of background on object perception. At present, the neural mechanisms by which scenes and objects interact remain unknown, leaving a critical gap in our understanding of these two major visual paths. The main goal of this multi-method proposal is to uncover the neural mechanisms of scene-object interactions. I therefore propose three competing theoretical models. A parallel model predicts only stimulus-driven representations of scenes and objects in the visual cortex. In contrast, interactive models predict that representations of scenes and objects in the visual cortex are influenced by one-another. However, whereas a visual-interactive model suggests direct interaction, a feedback model suggests that the interaction is mediated by frontal regions. To test this, I propose a novel psychophysical paradigm of seeing objects from scene context and scenes from object context. Thereby, I will examine how scene and object processing are affected by one-another and identify the potential neural sources of these modulations using fMRI (objective 1). Thereafter, I will use MEG to decode the timeline of these neural processes (objective 2). Establishing a clear neurocognitive model for scene-object interaction would not only advance our understanding of the two central paths of the ventral visual stream, but also significantly contribute to the definition of vision as an interactive system rather than a set of specialized parallel modules. Shifting from localized visual modules to interactive visual processes will broaden my expertise as a cognitive neuroscientist.", "To": ["2018-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["659778"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["KING'S COLLEGE LONDON"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Single Molecule Study of Protease Mechano-Specificity"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["MECHANOPROTEASES"], "Technology_Description": "Single-molecule enzymology offers new possibilities to dissect catalytic reactions that were previously unapproachable using biochemistry techniques conducted in the bulk. In particular, recent discoveries conducted at the single molecule level, such as the unanticipated force-mediated protein degradation pathway in the proteasome, highlight the close relation between mechanical forces and proteolysis in vivo. While much has been discovered about protein enzymology in the recent decades, the question of how mechanical force affects enzymatic catalysis remains vastly elusive. The main goal of this proposal is to understand the mechanobiology of proteolysis at the single molecule level. We will use the newly developed force-clamp spectroscopy technique, together with molecular biology engineering techniques and bioinformatics structural analysis to elucidate the molecular mechanisms that underlie protease catalysis under mechanical force. Successful enzymatic activity relies on the enzyme:substrate (E:S) assembly. Upon mechanical unfolding, proteins unveil their buried substrate sites, also called cryptic sites, thus favoring the formation of the E:S complex and ultimately permitting the subsequent chemical reaction. A key feature of recent mechano-chemistry experiments at the single bond level is that the rate at which the reduction of a protein disulfide bond occurs in the presence of a nucleophile is exponentially dependent on the stretching force. Hence, it is tempting to speculate that, in the case of an enzymatic reaction, the catalytic rate will be also force-dependent. We anticipate that the curved geometry of the bound substrate inhibits the E:S assembly at high-forces, implying a novel mechano-specificity character of proteases. Within a multidisciplinary approach, here we propose a series of innovative experiments to directly probe the effect of force on the kinetics of protease hydrolysis.", "To": ["2017-03-31, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-04-01"], "Project_ID": ["656721"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Role of Id4 in the adult subventricular zone of normal and injured brain"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["ID4"], "Technology_Description": "The aim of this proposal is to propose a scientific research project and a training plan for Dr. Brenda Rocamonde. The scientific research project aims to understand the function of the transcriptional regulator Id4 in the adult subventricular zone (SVZ) under physiological and pathological conditions. The SVZ is one of the largest neurogenic niches of the adult brain, generating new neurons from neural stem and progenitor cells, throughout adulthood. This region is activated after brain injury, such as ischemic stroke. Inhibitor of DNA binding 4 (Id4) is a transcriptional regulator that acts by antagonizing transcription factors. In the developing brain, Id4 is required for neural progenitor cell proliferation and differentiation. However, the function of Id4 in the adult SVZ has not been reported. We have observed that Id4 is expressed in neural stem cells and cells of the neuronal lineage in the adult SVZ. We propose to use in vivo approaches to (i) determine Id4 function in the SVZ by loss and gain of function approaches, and (ii) evaluate its role in the response of the SVZ to ischemic stroke, a major cause of disability in Europe. This project, undertaken in an international research center and carried out by a talented fellow will provide insights into the mechanisms underlying the regulation of adult neurogenesis in the normal and injured brain. In addition, we are proposing a career development plan for Dr. Rocamonde that includes training on scientific and transferable skills. This plan will widen Dr. Rocamonde\u2019s competences and provide her with the tools to become a leading independent researcher.", "To": ["2017-07-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2015-08-01"], "Project_ID": ["661044"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["Tensionless strings of six-dimensional superconformal theories"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["6D STRINGS"], "Technology_Description": "Despite the important role they play in M-theory, six-dimensional superconformal field theories (SCFTs) are to this day not well understood. A characteristic feature of 6d SCFTs is that their degrees of freedom include tensionless strings; while some properties of these strings have been studied in recent years, the 2d SCFTs that govern their behavior have not been constructed. In this proposal I outline a research plan to determine the 2d theories governing the strings, and use this knowledge to study the dynamics of six-dimensional SCFTs.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["708045"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Hydrocarbon Oxidation Mechanisms Elucidated from Radical scavenging"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["HOMER"], "Technology_Description": "Oxidation reactions of hydrocarbons are of central importance to both atmospheric and combustion chemistry, where they play a pivotal role in determining the capacity of a hydrocarbon to persist in the air or burn as a fuel. However, quantitative and complete measurements of the mechanisms by which oxidation occurs are very uncommon. Yet it is these mechanisms that ultimately determine the chemistry, influencing such diverse processes as tropospheric ozone production, secondary organic aerosol formation, soot formation and autoignition of fuels. Conventional approaches typically involve mimicking atmospheric or combustion conditions within a chemical reactor. Common to both of these chemical regimes are the phenomena of radical chain propagation, radical\u2013radical reactions and multiple reaction pathways, leading to complex reaction mixtures that evolve rapidly with time. Subsequent gas samples are subjected to detailed and often ambiguous interpretation, placing high demands on detailed chemical models in which only a small proportion of the reactions described within underwent direct experimental measurement. This fellowship seeks to challenge these existing approaches with an alternative methodology in which the short-lived initial products of oxidation, the alkyl radicals, are rapidly converted into stable halogenated species before reaction mixtures become complex, providing crucial information on the fundamental reaction steps at work in these systems. These mixtures will be analyzed by conventional, low cost gas-chromatography methodologies, where the inherent sensitivity and discriminating power of the electron-capture detector towards halocarbons will be exploited. By combining this technique with recent insights into radical scavenging using molecular halogens, a unique and diverse apparatus emerges, which will be used to interrogate several classes of reaction.", "To": ["2018-04-03, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-04-04"], "Project_ID": ["702794"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["The impact of Massive Binary Stars through Cosmic Times"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["BinCosmos"], "Technology_Description": "Massive stars, i.e. stars that are up to million times brighter than ordinary stars such as our Sun, play many important roles in astrophysics. They can be considered as (I) Cosmic Engines as they transformed the pristine and dark Universe left after the Big Bang into the modern Universe in which we live today. We use them as (II) Cosmic Probes to study the most distant galaxies and we monitor their eruptions and explosions as (III) Cosmic Transients. As a result, various fields in astrophysics heavily rely on the input of stellar models. Unfortunately, the widely used models are out-dated: they consider massive stars to be single. ", "To": ["2017-03-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-04-01"], "Project_ID": ["661502"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["Identification and characterization of the sex pheromone sensitive response gene(s) in the European Corn Borer males"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["ECBStrainShift"], "Technology_Description": "Night-active Lepidoptera are among the most speciose group of animals (~120.000 known species) and they possess a unique sexual communication system: females attract conspecific males by using a species-specific sex pheromone blend. Due to this fine-tuning, the development of novel pheromone systems is an evolutionary mystery: production of a new pheromone blend by females and preference for that blend by males must be established simultaneously, which is difficult to explain when the female blend and the male response are controlled by independently assorting genes. The pheromone strains of the European Corn Borer, Ostrinia nubilalis provide one of the best model system for a better understanding of pheromone (co)-evolution, because in these strains the females produce opposite proportions of E11- and Z11-tetradecenyl acetate, to which only strain-specific males are attracted. The genes responsible for the strain difference in female production are autosomally encoded and identified as fatty-acyl reductase while the gene(s) underlying male response has(have) been found to be sex-linked but have not been identified yet. For years they have been hypothesized to be olfactory receptors (ORs). However, we found with fine-scale mapping that the ORs map away from the Z-linked response locus and we showed two new candidate genes mapping at the male response region on the Z chromosome. The new candidates are involved in neurogenesis in other species and therefore are interesting for all olfaction and neurogenesis studies, including studies on humans. With our multidisciplinary experience, combining genetic engineering, neurophysiology and behaviour, we wish to identify the genetic change of the genes underlying male response in O. nubilalis and functionally characterize their involvement in olfaction. This approach has the potential to a) identify novel genetic mechanisms that underlie the evolution of pheromone communication and b) develop new pest management strategies", "To": ["2017-10-14, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-10-15"], "Project_ID": ["661322"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["TECHNISCHE UNIVERSITAET WIEN"], "EU_Contribution": ["EUR 166 156,80"], "Project_Title": ["Many-body effects in hybrid quantum systems"], "Total_Cost": ["EUR 166 156,80"], "Country": ["Austria"], "Project_ACR": ["MEHYB"], "Technology_Description": "The interdisciplinary field of hybrid quantum systems pursues the integration of different quantum systems from AMO and solid-state physics to harness their combined functionalities in an optimal way. Prominent examples are long-lived spin ensemble quantum memories for superconducting qubits or (opto-)mechanical quantum transducers, which are currently experimentally implemented for future quantum information processing applications.", "To": ["2017-03-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-04-01"], "Project_ID": ["657788"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["\u201cEPIgenetic impacts on early-stage SPECiation and adaptive radiation\u201d"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["EpiSpec"], "Technology_Description": "Phenotypic plasticity plays a key role at the onset of the speciation process, facilitating diversification though the induction of novel phenotypes in response to distinct environments. Via genetic accommodation and genetic assimilation, this influence may extend throughout the speciation process and beyond, into subsequent speciation events. While the epigenetic regulation of gene expression that mediates phenotypic plasticity has been extensively studied in lab-based model organisms, very little is known about epigenetic variation in natural populations. This project will be the first epigenetic study explicitly focused on the speciation process. Using cutting-edge techniques, the applicant will characterize DNA methylation variation within and among the sympatric species of a recently discovered endemic cichlid fish radiation in Lake Massoko, Tanzania. Specifically the applicant will test: if 1) newly formed species differ in the distributions of epigenetic marks across the genome, 2) genomic variants linked to phenotypic divergence among species are in genomic regions unusually high in DNA methylation, as expected under a hypothesis of epigenetic differences preceding fixed nucleotide differences during adaptive divergence, 3) genomic regions diverging in patterns of methylation among incipient species are also exhibiting high levels of methylation in populations of Astatotilapia calliptera, the ancestral, colonizing species. The results of this pioneering project will provide the first empirical evidence of the importance of epigenetic variation during the emergence of new species.", "To": ["2017-03-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-04-01"], "Project_ID": ["659791"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["KING'S COLLEGE LONDON"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["The role of innate lymphoid cells in regulating intestinal inflammation"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["Tbet ILC JFN"], "Technology_Description": "The maintenance of intestinal homeostasis has local and systemic implications for the host health and depends on a balance regulated by interactions between the immune system and the gut microbiota. Recently, it has become clear that a newly identified group of cells, innate lymphoid cells (ILCs), have a crucial role in intestinal homeostasis and host defence. ILCs respond rapidly to changes in the gut microenvironment and produce several cytokines that regulate intestinal inflammation. Although the pathways responsible for ILCs\u2019 development and differentiation are only starting to be elucidated, the transcription factor T-bet has emerged as a key regulator of these processes.", "To": ["2017-04-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-05-01"], "Project_ID": ["659882"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE FRANCIS CRICK INSTITUTE LIMITED", "Cancer Research UK"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Investigating eukaryotic replisome dynamics at the single molecule level"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["SMI REP"], "Technology_Description": "For cells to reproduce, an accurate duplicate of the genome must be created. This is no small task. The genetic information stored in each cell consists of ~6 billion pairs of nucleobases (base pairs, bp) assembled as a polymer 2 metres long and 2 nanometres in diameter, with the structural form of a double helix. For a mammalian cell to divide, this deoxyribonucleic acid (DNA) must be copied in a time frame on the order of 1 day, or ~70,000bp a second. DNA replication is common to all 3 domains of life, bacteria, archaea and eukarya and is accomplished by a complex of proteins. This proposal brings together a researcher of great proficiency in single molecule methods and multidisciplinary research with the Single Molecule Imaging group at the London Research Institute, one of the world leading centres in DNA replication. Combined, we will build unique instruments and develop single molecule assays to understand the molecular gymnastics of DNA replication in eukaryotes. We will elucidate rates of DNA unwinding by eukaryotic helicases and establish enhancements by association with other proteins. We will also study replisome dynamics by observing synthesis of DNA on custom templates in real time. This will allow detection of replication loops and stalling that may occur. We will also examine the mechanism of lesion bypass. The insight gained is impossible with classical biochemical techniques, as individual replisomes are observed in real time rather than measuring an average of a population. Our methods will reveal heterogeneities and obtain precise quantitative details of the dynamics. Features such as pauses and back slips will enable the study of intermediate states and conformational changes linked to replisome dynamics. This proposal will satisfy academic curiosity of understanding life at the most fundamental level but will also increase our knowledge of the how the cell works and thus becomes the building blocks for disease treatment and cures of the future.", "To": ["2017-07-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2015-08-01"], "Project_ID": ["657479"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["KING'S COLLEGE LONDON"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Characterization of islet-specific CD8 T cells in the honeymoon of type 1 diabetes"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["HONEYDIAB-8"], "Technology_Description": "Type 1 Diabetes (T1D) is a metabolic disease that results from the autoimmune attack against insulin-producing \u03b2-cells in the pancreatic islets of Langerhans. T1D usually comprises a phase called \u2018honeymoon\u2019, an interesting though poorly studied period of the disease where exogenous insulin requirements are decreased, postulating a possible attempt of \u03b2-cell regeneration and a remission of the autoimmunity. The proposed research aims to identify and characterize islet-specific CD8 T cells, the final effectors of \u03b2-cell death, in the honeymoon of T1D. We plan to perform a cross-sectional and longitudinal study with T1D patients where the immunological and metabolic characterization will be collected during the first year of the disease, and analysed by flow cytometry, enzyme immunoassays, gene expression and functional assays. ", "To": ["2018-09-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-15"], "Project_ID": ["704974"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITAET HAMBURG"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Interactions, Spins and Edges in Optical Lattices with Topological Band Structures"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["ISOTOP"], "Technology_Description": "Electrons in a magnetic field experience a drift transverse to their velocity, which gives rise to intriguing effects such as the whole family of Hall Effects. Interestingly, this drift can also appear without a charged particle and without magnetic field, i.e. for ultra-cold quantum gases in optical lattices with non-trivial topology, described by a Berry curvature. This enables researchers to use the tunability of quantum gases and allow for studies beyond the possibilities of condensed matter systems. Furthermore, it allows to mimic and study in great detail fascinating effects such as topological insulators and edge-states. Especially, the interplay between topology and interactions is not well understood and the existence of many interesting states, such as topological insulators, fractional Chern insulators and topological superfluids, is predicted, but have not yet been observed. In recent years, great progress has been made in engineering topological band structures for quantum gases. Whereas theoretical proposals are well developed, so far there are only few experimental realizations of topological band structures, especially for fermionic quantum gases. In this action, we want to create non-trivial topological band structures and explore (many-body) phases that can emerge for fermions and mixtures of bosons and fermions. We will map out the Berry curvature and study the detection of edge states, which provides a clear signature of a non-trivial topology. For the first time, we will realize a new creation and detection method for topological band structures and study high spin Fermi systems in topological optical lattices.", "To": ["2018-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["652837"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU"], "EU_Contribution": ["EUR 196 400,40"], "Project_Title": ["Software-defined Intermittent Networking"], "Total_Cost": ["EUR 196 400,40"], "Country": ["Norway"], "Project_ACR": ["SINet"], "Technology_Description": "In the ever-growing Internet of Things (IoT), Wireless Sensor Networks (WSNs) play an increasingly important role, with a strong demand for robust solutions in extreme environments. The aim of this proposal is to develop a networking solution that handles the intermittent communication links that characterise such environments.", "To": ["2018-05-01, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-05-02"], "Project_ID": ["699924"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Building a computational basis for the brain response in the left ventral occipito-temporal cortex: Understanding the Sparse Familiarity Model of visual word recognition"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["SFM4VOT"], "Technology_Description": "The left ventral occipito-temporal cortex (lvOT) is an integral part of the ventral visual processing stream and is consistently activated in response to visual words. Recently, I developed a computational implementation of the lvOT functioning during visual word recognition, the sparse familiarity model (SFM). The single assumption of the SFM is that the statistical patterns of letter string familiarity are the fundament of lvOT functioning. The SFM is able to simulate prominent lvOT benchmark contrasts and its simulations predict brain activation of the lvOT in multiple fMRI studies. The main aim of the present proposal is to use the model to systematically investigate hotly debated topics in word recognition research concerning current theoretical approaches for the lvOT: (1) The influence of learning and (2) domain specificity (i.e. for words) vs. generalization (i.e., to face and object recognition) of lvOT function and neuronal populations. In the course of these investigations, the SFM will be developed into a learning model and a generalized model for word, face, and object recognition. Central to this will be high-density electrophysiological measurements (MEG) that sample brain activation with high temporal resolution and reasonable spatial resolution, to allow connectivity analysis at different time points. The MEG measurement, in addition to fMRI measures, will be essential to test theoretical assumptions concerning the proposed two stages of the SFM that differ fundamentally in terms of neuronal and cognitive mechanisms. Critical will be the association of these stages to different time windows and assumptions about the brain networks involved. The host, Prof. Fiebach at Frankfurt University, has a strong focus on the neurocognitive basis of language and access to an MEG, which is essential for realizing this project. To summarize, the goal of the project is to establish the sparse familiarity model and extend its functioning to resolve current debates.", "To": ["2018-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-04-01"], "Project_ID": ["707932"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["A multi-method perspective on children's use of rehearsal in serial recall tasks"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["MMPCURSRT"], "Technology_Description": "Rehearsal is a key construct in models of immediate memory and refers to the overt or covert repetition of items to counteract forgetting. A long-standing assumption is that children younger than 7 years do not engage in rehearsal, as such children tend not to show key \u2018experimental effects\u2019 thought to be signatures of rehearsal. However, given a growing debate in the adult experimental literature on the interpretation of these effects, and more recent concerns in the developmental literature about how one should understand changes in their magnitude, the questions of when rehearsal develops, and the role that it plays in supporting serial recall in children become open once again.", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["707141"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["NonAdiabatic Molecular Dynamics of organic Intermediates in Atmospheric chemistry"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["NAMDIA"], "Technology_Description": "Earth\u2019s atmosphere is a massive photochemical reactor, and human activities are changing its chemical composition, impacting both climate and air quality. Detailed chemical mechanisms \u2013 constructed from coupled kinetic networks of thousands of elementary reactions \u2013 are crucial in advancing our fundamental understanding of atmospheric chemistry, and developing reliable predictive models. Because the elementary mechanistic details of volatile organic compound (VOC) oxidation are often beyond the reach of experiment, in silico molecular kinetics studies (utilizing ab initio quantum chemistry and nonequilibrium statistical mechanics) are increasingly used to construct atmospheric chemistry models \u2013 particularly for describing VOC kinetics on electronic ground states.", "To": ["2018-05-01, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-05-02"], "Project_ID": ["701355"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Dangerous Masculinities: Young Men in Italian Cinema of the 1940s-1960s"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["Young-Italian 2015"], "Technology_Description": "The present project aims to examine Italian cinema during the twenty-year period from 1943 to 1963 in relation to the construction of the image of the young Italian man. The main goals are to understand how Italian cinema from the post-war period to the \u2018economic boom\u2019 gave substance to male national identities and to situate those identities within an emerging youth culture produced by the new consumer society in Italy.", "To": ["2018-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-11-01"], "Project_ID": ["704227"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Accounting for genocide: legal and scientific accounting practices in the wake of the Srebrenica genocide"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["Genocide accounting"], "Technology_Description": "\u201cAccounting for genocide\u201d empirically considers two sociomaterial practices of accounting for the 1995 Srebrenica genocide in Bosnia and Herzegovina. First, it scrutinizes efforts of national and international organizations to (ac)count how many Bosniak men were massacred and who was killed in July 1995. The second question about accounting analyses how those politically responsible at the time of the genocide are legally tried at the International Criminal Tribunal for the former Yugoslavia (ICTY). The first practice of accounting is based on inter alia forensic science, statistics, missing persons lists and witnesses conveniently subsumed under \u2018atrocity victim identification\u2019 (AVI), the second practice is the domain of adversarial legal proceedings, developing international criminal law, transitional justice and controversies over the Srebrenica genocide and legitimacy of the ICTY. A rigorous qualitative analysis focusing on the various locations\u2014mass-graves, family assistance centres, forensic laboratories, the ICTY, public domain\u2014where objects like remains, missing persons, identities, crimes, DNA evidence, and legal cases come to matter provides a deep understanding of the question of how both practices of accounting become entangled and co-construct each other.", "To": ["2017-12-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["660707"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["LINKOPINGS UNIVERSITET"], "EU_Contribution": ["EUR 173 857,20"], "Project_Title": ["Transistor sensors for in-vivo sucrose monitoring in plants"], "Total_Cost": ["EUR 173 857,20"], "Country": ["Sweden"], "Project_ACR": ["Trans-Plant"], "Technology_Description": "In order to address the challenge of undernourishment we need to understand better how plants grow, how they interact with their environment, and how to increase plants\u2019 productivity. During the past decades important progress has been made in plant biology due to the development of genetic and genomic tools. Still many questions remain unanswered highlighting the need for the development of complementary technologies to genetic methods. Plants\u2019 growth and productivity are determined by photosynthesis and the way its products, such as sucrose, are distributed and utilized during the growth and development of the plant. The goal of Trans-Plant is the development of a complementary technology based on organic bioelectronics that will allow in-vivo sucrose monitoring in the vascular tissue of the plant from source to sink and give new insight to the transport mechanism of sucrose. This project will focus on interfacing organic bioelectronics with plants and developing the devices in-vivo where the plant\u2019s complex structure consists of an integral part of the device. It will open up new possibilities for monitoring and controlling physiology in plants and result in the development of a state of the art device concept and technique for organic bioelectronics and plant science. During the fellowship Eleni Stavrinidou will be trained to develop a unique set of expertise, she will gain new knowledge and skills in more than one discipline, she will acquire transferable skills and she will expand her scientific and industrial network through collaborations and meetings. Therefore this fellowship will accelerate her scientific and professional development.", "To": ["2018-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-11-01"], "Project_ID": ["702641"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Assessing the aerosol radiative impact employing advanced methods to reduce uncertainties in the aerosol optical properties"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["REDRAF"], "Technology_Description": "Understanding how anthropogenic aerosols impact the Earth\u2019s climate system is a daunting challenge. Aerosol radiative effects are strongly dependent on the optical and microphysical properties of the particles. Uncertainties in the absorption coefficient and the single scattering albedo (SSA) contribute significantly to the overall uncertainties in the optical properties of aerosol and their radiative effect. Not only does hydration cause an increase in size, but it also alters the complex refractive index (RI) of the particle; the real part of the RI governs the scattering of light by the aerosol and the imaginary part the degree of absorption. Thus, quantifying the relationships of chemical composition, relative humidity (RH) and particle phase with complex RI is critical for predicting the aerosol radiative forcing. Since these optical properties determine the magnitude and even the sign of the effect of aerosol on the Earth\u2019s energy balance, it is vital that we understand their range. Although techniques have been developed to measure the scattering and absorption cross-sections of ambient and laboratory particles, interpreting measurements can be challenging. Using a new technique to accurately determine the extinction cross-sections of single particles developed in the Bristol laboratory, we will provide a rigorous assessment of treatments used to characterise the optical properties of aerosol. Of particular emphasis, we will examine the optical properties of mixed-component aerosol and the influence of chemical aging of organic aerosol on light absorption. Crucially, the parameterisations for optical properties that result will then be used to refine (and assess sensitivities of direct forcing to) the treatment of aerosol properties in radiative transfer and global climate models. This work will also provide crucial information to improve our understanding of field and remote sensing instruments.", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["700843"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["The environmental fate and effects of microplastics in freshwater ecosystems"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["FreshwaterMPs"], "Technology_Description": "EU member states are currently working towards the realisation of environmental goals specified in the Water Framework Directive (WFD), which aims to protect both human and ecosystem health. Microplastic particles (MPs) are emerging pollutants of increasing concern and are formed primarily when plastic waste degrades in the environment. The impacts of MPs on freshwater biota are not known, however, they may present a potentially persistent and ecotoxicological pollution problem. Accordingly, the goal of this project is to assess the environmental risk of MPs in freshwater habitats. To achieve this, a detailed investigation of MP environmental persistence will be carried out. This will provide environmental fate summaries for different polymer classes and enable the modelling of their degradation processes. This will be combined with laboratory studies to assess relevant sub-lethal endpoints such as reproduction, fitness, inflammation, and oxidative stress. As MPs are known to accumulate co-occurring organic pollutants, the toxicity of virgin MPs will be compared to MPs conditioned with relevant freshwater pollutants. This work will build towards a sophisticated state-of-the-art mesocosm study that will evaluate both MP fate and impacts in model ecosystems. The establishment of a novel framework for the environmental risk assessment of MPs will inform our ability to achieve conservation objectives taking into account MPs as emerging pollutants. The merit of this is that protection goals may be better accommodated in policy and management through the generation of so far unavailable data on MP persistence and environmental toxicity. Taken together, the project will generate so far unavailable data sets to assess for the first time the environmental impacts of freshwater MPs. Thus, the outcomes will highly relevant for academia, politics, stakeholders and society.", "To": ["2017-03-31, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-04-01"], "Project_ID": ["660306"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["KING'S COLLEGE LONDON"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Genetic analysis of rare and common variation in a large Brazilian bipolar family"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["BBFGEN"], "Technology_Description": "This proposal describes my aim to use a uniquely large multigenerational family to better understand the genetic underpinnings of mood disorders: the Brazilian Bipolar Family (BBF). The family has a high incidence of mood disorders, featuring diminishing age of onset over generations and assortative mating, whereby many of the marriages in the family are between individuals with a psychiatric disorder. Mood disorders are leading contributors to the global burden of disease. Bipolar disorder is characterized by periods of elevated mood and periods of depression. Major depressive disorder is characterized by pervasive and persistent low mood, low self-esteem and loss of interest or pleasure in normally enjoyable activities. Heritability estimates are 37% for MDD and up to 75% for BP. The current picture for complex disorders is of a genetic architecture consisting of both common and rare variants contributing risk. Genetic studies of mood disorders have not yet individual variants/genes accounting for a large increase in risk. The effect of common variants in the family context is unclear. I propose to utilize the BBF as a unique resource for studying both common and rare variation in mood disorders. Its size offers a powerful means for mapping genetic loci for mood disorders that are individually rare but common within the family. It also provides us with a unique model in which to analyse individual genetic risk profiles, utilizing the large sample size of and predictive ability of previous case-control association studies for each family member into a polygenic risk score. This will also allow me to assess assortative mating, which may act to increase polygenic risk to mood disorders over generations. I will develop an approach which will allow me to incorporate genome-wide case-control study results into family studies \u2013 something with broad utility for the field. My study will shed light on the genetic pathology of mood disorders, aiding prevention and treatment.", "To": ["2017-04-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-05-01"], "Project_ID": ["658195"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Improved Fluid Dynamics for Relativistic Heavy Ion Collisions"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["IMFDforHIC"], "Technology_Description": "One of the fundamental questions in the field of high-energy physics is what are the properties of strongly interacting matter at high temperature or density, when one expects a transition from hadronic degrees of freedom to deconfined matter, quark-gluon plasma (QGP), where the degrees of freedom are quarks and gluons. ", "To": ["2017-12-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["655285"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["KING'S COLLEGE LONDON"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["The Making of Modernist Resistance, 1880-1950"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ssmscaifa"], "Technology_Description": "The vibrant diversity of an increasingly global modernity owes much to the cross-cultural exchanges between British and Indian modernists during their collaborations in civil rights, anti-colonial, and anti-fascist activism from the 1880s to the 1950s. The proposed project examines the shifting nature of literary and political contributions to activist movements made by four such networks of British and Indian modernists to illuminate their integral role in creating what I contend is a distinctively modernist resistance. As early as the 1880s, theosophists from Britain partnered with renowned Indian spiritualists to bridge cultural gaps between colonizer and colonized through shared mystical experiences to emphasize an innate unity among human beings. By 1919, however, the disillusionment following World War I coupled with India\u2019s outrage about the Amritsar Massacre in which General Dyer and his troops opened fire killing hundreds of innocent Indians, supplanted such yearnings for unity with efforts to protect democratic freedoms from threats by right-wing extremists through a secular socialist resistance. Mulk Raj Anand, initially drawn to the liberal humanism of the Bloomsbury Group eventually joined the radical socialists of India\u2019s Progressive Writers Association in 1936. Women like Sarojini Naidu and Virginia Woolf fought for women\u2019s equality and opportunities to join in anti-right-wing resistance. Mahatma Gandhi and Jawaharlal Nehru, influenced by the socialist ideologies of the Fabian Society, incorporated them into Indian nationalism and governance. This study explores the relationship between the ideologies of these networks to establish what the shift from spiritualism to secular socialist nationalism reveals about the nature of modernist resistance and the conditions of modernity that inspired it. The world view underpinning this resistance was integral in defining the post-war identities of Britain and India as secular socialist-leaning democracies.", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["659376"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM", "UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Precision Multi-Scale Predictions for the LHC: Higgs, Jets and Supersymmetry"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["MULTISCALE"], "Technology_Description": "My project will boost the precision of theoretical predictions for collisions at the Large Hadron Collider. Precise predictions are crucial to further constrain the properties of the recently-discovered Higgs boson, and uncover a faint signal of Beyond-the-Standard Model physics. I will focus on the strong interactions, which dominate the theoretical uncertainty and play a role at multiple energy scales, including those related to the incoming protons, the hard scattering, the masses of (new) particles, the transverse momentum and size of jets.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["677323"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI TRENTO", "UNIVERSITA DEGLI STUDI DI TRENTO"], "EU_Contribution": ["EUR 1 499 678"], "Project_Title": ["The Home-Migration Nexus: Home as a Window on Migrant Belonging, Integration and Circulation"], "Total_Cost": ["EUR 1 499 678"], "Country": ["Italy", "Italy"], "Project_ACR": ["HOMInG"], "Technology_Description": "The experience of home lies at the core of everyday life, but only through migration is it revealed as a complex and elusive social construction, whose micro analysis illuminates macro social issues and problems. How home works in the life trajectories of those who left it behind, and what the search for home says of immigrant integration and of the influence of mobility on domesticity, are the central questions of HOMInG. By deconstructing the tension between the static face of home and the dynamic face of migrant lives, this programme marks a turning point in the study of the social and emotional appropriation of space. It builds on a mixed-method research design on home as experienced by labour and forced migrants, under different household arrangements, compared across several countries and groups of reference. ", "To": ["2021-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-11-01"], "Project_ID": ["678456"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Electrophile-Mediated Three-Component Enantiospecific Cross-Couplings"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["EMTECS"], "Technology_Description": "One of the most challenging aspects of Suzuki-Miyaura reactions is the stereospecific cross-coupling of sp3 substituted boronic esters with aryl halides. Recently, the host group developed a metal-free, stereospecific cross-coupling reaction of chiral alkyl boronates with electron-rich aromatics, promoted by the use of electrophilic oxidants. This proposal seeks to substantially extend this cross-coupling chemistry through the application of a range of different electrophiles that will not only mediate the cross-coupling process, but also remain in the final product, creating multiple carbon\u2013carbon bonds stereospecifically. In particular, the application of electrophilic organometallic species will be investigated so as to take advantage of the power of metal catalysts in the formation of carbon\u2013carbon bonds. Through the use of this strategy, doubly functionalised enantiopure aromatic compounds may be formed in a very efficient three-component coupling process that utilises readily accessible enantiopure alkyl boronic esters, electron-rich aromatics and catalytically generated organometallic electrophiles.", "To": ["2017-02-28, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-03-01"], "Project_ID": ["652890"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["Wnt Enhancer LandscapE CharacTerization"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["WntELECT"], "Technology_Description": "Despite significant efforts, cancer remains one of the major health challenges in Europe.", "To": ["2018-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["706443"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITY OF BRISTOL", "UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 1 998 546"], "Project_Title": ["Bird Inspired Autonomous Flight"], "Total_Cost": ["EUR 1 998 546"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["BIAF"], "Technology_Description": "The agile and efficient flight of birds shows what flight performance is physically possible, and in theory could be achieved by unmanned air vehicles (UAVs) of the same size. The overall aim of this project is to enhance the performance of small scale UAVs by developing novel technologies inspired by understanding how birds are adapted to interact with airflows. Small UAVs have the potential to dramatically change current practices in many areas such as, search and rescue, surveillance, and environmental monitoring. Currently the utility of these systems is limited by their operational endurance and their inability to operate in strong turbulent winds, especially those that often occur in urban environments. Birds are adapted to be able to fly in these conditions and actually use them to their advantage to minimise their energy output.", "To": ["2021-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-04-01"], "Project_ID": ["679355"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["UNIVERSITE DE CAEN NORMANDIE", "UNIVERSITE DE CAEN NORMANDIE"], "EU_Contribution": ["EUR 1 153 750"], "Project_Title": ["Theory of Stein Spaces in Berkovich Geometry"], "Total_Cost": ["EUR 1 153 750"], "Country": ["France", "France"], "Project_ACR": ["TOSSIBERG"], "Technology_Description": "Complex Stein spaces may be thought of as analytic analogues of the affine schemes of algebraic geometry. They may be characterized in several manners: using convergence of holomorphic functions, topological properties or potential-theoretic properties, for instance. Especially useful for applications is the fact that their coherent cohomology vanishes. Despite the crucial importance of this theory in complex analytic geometry, its p-adic counterpart has hardly been sketched.", "To": ["2020-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-07-01"], "Project_ID": ["637027"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["KING'S COLLEGE LONDON"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Multi-modal interrogation of instinctive behaviours and intrahypothalamic connectivity"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["DRIVOME"], "Technology_Description": "Mammalian behaviour is driven by instincts such as hunger, sex and aggression which are familiar to everyone from daily experience. Anomalies in these instincts cause disorders such as anorexia, excessive sexual drive and episodic dyscontrol syndrome, and potentially also psychologically difficult situations like marital infidelity. Neuronal circuits that drive these instincts reside in the hypothalamus where research is gaining pace rapidly.", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["701986"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM", "UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 1 748 656,25"], "Project_Title": ["Migration as Development"], "Total_Cost": ["EUR 1 748 656,25"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["MADE"], "Technology_Description": "How do processes of development and social transformation shape human migration? More specifically, how do development process affect the geographical orientation, timing, composition and volume of both internal and international migration? The relation between development and human mobility is highly contested. While economic development in poor countries and areas is usually seen as the most effective way to reduce migration, other studies suggest that development actually increases migration. However, evidence has remained highly inconclusive so far because of theoretical and methodological limitations. ", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["648496"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["UNIVERSITY OF DUNDEE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Unravelling PIM kinase signal integration in the T cell response"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["PIM PROTEOMICS"], "Technology_Description": "Understanding how T cells integrate alternative signal combinations to determine immune response strength and functionality is of critical importance for rational design of immunomodulatory therapies. The PIM kinase family have been identified as important regulators of cell division, survival and protein synthesis independent of, but in parallel to the key signalling molecule mTOR. I propose to use cutting-edge quantitative proteomic technology to identify substrates and downstream protein networks regulated by PIM kinase in activated T cells. I will investigate where these downstream targets qualitatively diverge from, or quantitatively interact with, the mTOR signalling pathway (Objective 1 and 2). Using advanced cell culture and mathematical modelling I will quantify how this co-ordinated activity regulates T cell division, survival and differentiation outcomes (Objective 3). This comprehensive exploration of PIM kinase and mTOR signalling pathway integration will provide important fundamental insight into how these signals combine to regulate T cell fate and may be manipulated in the context of immunotherapy or cancer.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["705984"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["KING'S COLLEGE LONDON"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Cortical circuit assembly in the developing mouse neocortex"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["CorCir"], "Technology_Description": "The developing neocortex consists of two major neuronal subtypes\u2013pyramidal neurons and interneurons. These two subtypes come together in the cortical plate, forming cortical circuits that can integrate and respond to external and internal stimuli. Despite recent advancement in the research on cortical networks of the developing brain, the mechanism involved in cortical circuit assembly remains relatively unexplored. This project aims to identify the sequence of events and factors involved in cortical circuit assembly in the developing mouse brain. As such, this project can be broadly divided into three main parts namely lamination, synaptogenesis and maturation of the MGE interneurons specifically. Currently, the exact mechanisms that govern MGE interneurons are still unknown except that it may involve cues that are produced by the pyramidal neurons. Therefore, we aim to use existing transcriptome data of the different neuronal layers coupled with the acquisition of the early- and late- born MGE interneurons transcriptome in order to identify the receptor-ligand pair that is involved in the specific lamination of MGE interneuron. We also aim to understand the sequence of events that occur during synaptogenesis and maturation of MGE interneurons. To achieve this, we will be performing live imaging on organotypic brain slices of sparsely labeled MGE interneurons and by selectively killing specific classes of interneurons in order to determine the effect of these cells on the maturation of the parvalbumin-expressing interneuron. Altogether, this proposed project will give a better insights into the factors and mechanisms underlying cortical circuit assembly in the developing brain and will pave the way for a better understanding into the aetiology of certain neurodevelopmental disorders.", "To": ["2019-08-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-15"], "Project_ID": ["705311"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE UNIVERSITY OF EDINBURGH", "THE UNIVERSITY OF EDINBURGH", "UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 1 457 185"], "Project_Title": ["Induction of Broad-Coverage Semantic Parsers"], "Total_Cost": ["EUR 1 457 185"], "Country": ["United Kingdom", "United Kingdom", "Netherlands"], "Project_ACR": ["BroadSem"], "Technology_Description": "In the last one or two decades, language technology has achieved a number of important successes, for example, producing functional machine translation systems and beating humans in quiz games. The key bottleneck which prevents further progress in these and many other natural language processing (NLP) applications (e.g., text summarization, information retrieval, opinion mining, dialog and tutoring systems) is the lack of accurate methods for producing meaning representations of texts. Accurately predicting such meaning representations on an open domain with an automatic parser is a challenging and unsolved problem, primarily because of language variability and ambiguity. The reason for the unsatisfactory performance is reliance on supervised learning (learning from annotated resources), with the amounts of annotation required for accurate open-domain parsing exceeding what is practically feasible. Moreover, representations defined in these resources typically do not provide abstractions suitable for reasoning.", "To": ["2021-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["678254"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["TECHNISCHE UNIVERSITAET WIEN"], "EU_Contribution": ["EUR 166 156,80"], "Project_Title": ["Entangled Twin Atom Beams"], "Total_Cost": ["EUR 166 156,80"], "Country": ["Austria"], "Project_ACR": ["ETAB"], "Technology_Description": "Many of the fascinating phenomena predicted by quantum mechanics, like non-local correlations and entanglement, were implemented with photons in the framework of quantum optics. It is today a mature field with applications emerging in cryptography, random number generation, and quantum computation. Based on the analogy between matter waves and electromagnetic waves and on particle-wave duality, quantum atom optics started to develop recently, thanks to the development of tools for matter wave manipulation. A crucial point for the success of quantum optics was the availability of twin-photon sources, based on a non-linear medium. Very recently, several approaches towards realizing twin-atom pairs have been investigated (most notably by the applicant and the host institution of this proposal) and successfully realized. The ETAB project will use this new twin atom beam (TAB) source to implement quantum atom optics experiments. Characterization of the resulting strongly correlated states will be performed through measurement of correlation functions. These experiments will go beyond the analogy with quantum optics due to fundamental differences between atoms and photons: mass and intrinsic nonlinearity due to interactions. This second property allows high efficiency twin atom beam generation, with an important pump depletion. This allows us to investigate new physics, including beyond linear response, quantum simulation, and non-equilibrium physics. Furthermore, by preparing the twin beams in an entangled state, we will perform the first test of Bell inequalities with untrapped atoms, which could rule out spontaneous decoherence or gravitational nonlinearity models.", "To": ["2017-03-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-04-01"], "Project_ID": ["656530"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["KING'S COLLEGE LONDON", "KING'S COLLEGE LONDON"], "EU_Contribution": ["EUR 1 759 064"], "Project_Title": ["Quantum Black Holes: A macroscopic window into the microstructure of gravity"], "Total_Cost": ["EUR 1 759 064"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["QBH"], "Technology_Description": "The thermodynamic behavior of black holes is a precious clue in unravelling the microscopic structure of quantum gravity. High precision computations of quantum black hole entropy provide a new window into the fundamental microscopic theory of gravity and its deviations from classical general relativity. Traditional methods of quantum field theory have proved to be not well-suited to perform these computations. Two breakthroughs in my recent work establish new ground for progress.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["681908"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["UNIVERSITAET BERN", "UNIVERSITAET BERN", "THE UNIVERSITY OF READING", "MODUL UNIVERSITY VIENNA GMBH"], "EU_Contribution": ["EUR 1 952 183"], "Project_Title": ["Indigenous Communities, Land Use and Tropical Deforestation"], "Total_Cost": ["EUR 1 952 183"], "Country": ["Switzerland", "Switzerland", "United Kingdom", "Austria"], "Project_ACR": ["INCLUDE"], "Technology_Description": "Tropical deforestation is an important contributor to climate change, through the release of significant amounts of carbon in the atmosphere. The main proximate cause of deforestation in tropical regions is agricultural expansion, followed by timber extraction. The general objective of this research is to understand how the interaction of technological, environmental, economic and social factors influence land use dynamics, including household decisions, about agricultural expansion and resource extraction in sensitive tropical regions. More specific questions relate to the role of various governance structures, particularly those recognizing common property regimes of land tenure to indigenous and rural communities, and the deliberative evaluation about the opportunity of reforming such structures in order to reduce deforestation and forest degradation. Although such aspects have been addressed in a variety of contexts, the approach proposed here is novel as a) it explicitly models the interaction between institutional, environmental, technological and socio-economic factors at different spatio-temporal scales, b) it specifically focuses on the governance structures associated with different land tenure regimes through the lenses of Social Network Analysis (SNA), c) uses a Q-methodology framework to develop a participatory approach to study stakeholders\u2019 perspectives and attitudes on the necessary governance interventions to prevent deforestation and forest degradation and d) it assesses the relationships between agricultural expansion, deforestation, governance structures and stakeholders\u2019 attitudes, with particular attention to the sensitivity of household land use decisions and resource extraction. In order to meet the research objectives, this project will focus on the province of Salta in the dry Chaco in North-Western Argentina, a region characterized by high rates of land cover change and the presence of indigenous/rural communities.", "To": ["2021-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-11-01"], "Project_ID": ["681518"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["UNIVERSITE MONTPELLIER III PAUL VALERY"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["The Court of Elizabeth I \u2013 A European Drama"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["COEED"], "Technology_Description": "The enduring fascination in anglophone research with the political culture of Elizabethan England has often served to occlude the fact that responses to the Tudor monarch were formulated across renaissance Europe. A pan-European range of dramatic texts bears witness to the anxiety and consuming interest which surrounded Elizabeth I. Such texts have often been neglected or referenced briefly as points of illustration. Moreover, these texts (where afforded any consideration) have most commonly been seen in terms of national traditions of literary production, rather than integrated into a Europe-wide vision of cultural debate and exchange. None of these texts has been considered in recent centuries for their theatrical potential or placed in close conversation with Elizabethan (or post-Elizabethan) literary production. ", "To": ["2018-10-02, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-10-03"], "Project_ID": ["702104"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["KING'S COLLEGE LONDON"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Regulation of lipid-mediated immunity in the intestine"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["LIPID IMMUNITY"], "Technology_Description": "The gastrointestinal tract is continuously exposed to multiple antigens from commensal bacteria, food and pathogens. The mechanisms by which the gut mucosa tolerates trillions of commensal bacteria without developing inflammation remains poorly understood. It is increasingly appreciated that commensal bacteria-derived products regulate the homeostasis and/or function of many immune cell populations. Commensal bacteria-derived lipids are recognized by a population of unconventional T cells, called NKT cells. NKT cells specifically recognize through their T cell receptor lipid antigens presented by the MHC-I-like molecule CD1 which is expressed by a variety of immune cells within the intestinal tissue. Importantly, commensal-derived lipids modulate the numbers, phenotype and function of intestinal NKT cells. Conversely, dysregulation of NKT cell activation and/or CD1 expression have been associated with the development of colitis in mice and humans. Despite the abundance and diversity of microbial-derived lipids present in the gut, the molecular and cellular mechanisms that mediate their recognition by immune cells and the identity of the antigen presenting cells involved in this process remain unknown. By using a combination of multiparametric flow cytometry, genetic engineering and in vivo experiments this proposal aims to unravel the mechanisms and functional consequences of lipid-presentation in the mucosa. These studies will provide a better understanding of the factors that modulate intestinal immunity, with the potential to improve therapies for patients suffering from intestinal inflammatory diseases and possibly a broader range of disorders.", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["703639"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["KING'S COLLEGE LONDON", "KING'S COLLEGE LONDON"], "EU_Contribution": ["EUR 1 993 802,59"], "Project_Title": ["Dissecting the cellular mechanics of contact inhibition of locomotion"], "Total_Cost": ["EUR 1 993 802,59"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["CIL2015"], "Technology_Description": "Our aim is to dissect the mechanisms of contact inhibition of locomotion (CIL), a process whereby migrating cells collide and repel each other, as it is now clear that CIL is pivotal to understanding embryogenesis and pathologies such as cancer. We have developed an in vivo model using Drosophila macrophages (hemocytes), along with novel analytical tools, to examine the contact inhibition response in cells during development. We therefore have an unprecedented opportunity to address CIL in a genetically tractable organism within a physiologically relevant setting. This model has revealed that a precisely controlled CIL response is a significant driving force behind the acquisition of embryonic patterns, and recent data show that this precision requires a series of synchronized changes in cytoskeletal dynamics. Our central hypothesis is that key to this cellular \u2018dance\u2019 is mechanosensation of the collision, which integrates subsequent signaling mechanisms to choreograph the steps of the contact inhibition process. The first part of this proposal will elucidate the molecular mechanisms controlling CIL by exploiting our unique ability to live image and genetically dissect this process in Drosophila. We will also take an interdisciplinary approach to elucidate the mechanical aspects of the response, which will allow us to examine the feedback between signaling pathways and the physical forces of the CIL response. We will subsequently extend our detailed understanding of the CIL process, and our novel set of analytical tools, to mammalian cell types and model systems. This will allow us to develop new assays to directly probe the mechanics of CIL and begin to investigate the function of this underexplored process in other cell types. This in depth knowledge of the response places us in the best position to extend our understanding of CIL to new physiologically relevant scenarios that in the future will impact on human health.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["681808"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM", "UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 1 999 012"], "Project_Title": ["Children and social robots: An integrative framework"], "Total_Cost": ["EUR 1 999 012"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["CHILDROBOT"], "Technology_Description": "Robots used to be made for labor; now, they are increasingly also made for relationships. Social robots can learn from us, teach us, play with us, and assist us. With the market for social robots expected to grow substantially in the next 20 years, social robots are likely to become a life-changing technology similar to personal computers or smart phones. Still, we still know little about one of the most intriguing, relevant, and timely issues in this process \u2013 children\u2019s interaction with social robots. Children are not only increasingly recognized and targeted as early adopters of new technologies; they may also be more susceptible to potential effects of interacting with robots than are adults.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["682733"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Molecular palaeobiology and comparative genomics of chelicerate terrestrialisation"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["CheliceLand"], "Technology_Description": "Animals have marine origins, with only three phyla including lineages that can complete every phase of their life cycle outside of water\u2013saturated environments. These phyla are the Vertebrata (reptiles, birds and mammals), the Mollusca (land snails and the slugs) and the Arthropoda (e.g. insects, spiders, centipedes). The process through which animals adapted to life on land is referred to as terrestrialisation and it is one of the most fascinating unresolved problems in evolutionary biology. The crossing of the water\u2013land barrier was the most extreme case of adaptation to a new environment in animal history. In fact, the difference between the sea and the subaereal environment is so extreme that astrobiology uses terrestrialisation as an analog to study how life could adapt to a new planet. ", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["655814"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM", "UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Exploring the Plurality of New Worlds: Their Origins, Climate and Habitability"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["EXO-ATMOS"], "Technology_Description": "Recent surveys have revealed an amazing, and yet unexplained, diversity of planets orbiting other stars. The key to understanding and exploiting this diversity is to study their atmospheres. This is because exoplanets\u2019 atmospheres are unique laboratories that hold the potential to transform our understanding of planet formation, physics, and habitability. This is a new opportunity to place the Solar System and the Earth\u2019s ecosystem in a broader context; one of the main goals of modern astrophysics.\u00a0", "To": ["2021-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["679633"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["UNIVERSITY OF BRISTOL", "UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 1 986 356"], "Project_Title": ["Bio-Inspired Tools for Glycoscience"], "Total_Cost": ["EUR 1 986 356"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["GLYCO-TOOLS"], "Technology_Description": "Cell surface carbohydrates play key roles in cell recognition mechanisms. O-glycosylation is a ubiquitous post-translational modification that is highly dynamic and responsive to cellular stimuli through the action of cycling enzymes. Expression of specific O-glycans is linked to changes in gene expression in, for example, inflammatory bowel disease, cystic fibrosis and several types of cancer. ", "To": ["2020-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-07-01"], "Project_ID": ["648239"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM", "UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 1 499 938"], "Project_Title": ["The mind's eye: How expectation and attention shape perception"], "Total_Cost": ["EUR 1 499 938"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["PERCEPT"], "Technology_Description": "Perception is more than meet\u2019s the eye; how we see the world is critically shaped by attention (what is relevant) and as a growing body of work indicates, by past experience (what is likely). Overturning the classical notion of perception as a largely bottom-up process, the idea that our brain is a prediction machine, continually trying to predict what is \u2018out there\u2019 based on past experience, is quickly growing in stature and influence. Yet, little is still known about how predictions shape perceptual experience. Moreover, it is completely unknown to what extent predictive processing occurs automatically. Lastly, how the brain ultimately \u2018decides\u2019 on one hypothesis or interpretation of the current sensory state is still unclear. The proposed research program will address these outstanding questions with the ultimate aim to better understand how the brain infers the world and the mechanisms that give rise to perceptual experience. It will do so through an integrated application of psychophysical, neuroimaging, brain stimulation, mathematical modelling, and pharmacological techniques. The research program comprises three projects. The first project will examine how expectations are implemented in the brain and shape stimulus processing, independently from and aided by attention. The second project will reveal if one can teach oneself to be free of expectation and associated habitual responding, through intensive mental training, as cultivated by meditation. The third project will test the idea that the striatum, a subcortical brain region, and its irrigation by the neurotransmitter dopamine play a critical role in updating our internal model about the environment and thereby conscious perception. The proposed research will be critical in elucidating the mechanisms that underlie experience and the extent to which these mechanisms are plastic, and will have important implications for the study of clinical disorders characterized by dysfunctional experience of the world.", "To": ["2021-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-08-01"], "Project_ID": ["679399"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM", "UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 1 996 362,50"], "Project_Title": ["The Logic of Conceivability: Modelling Rational Imagination with Non-Normal Modal Logics"], "Total_Cost": ["EUR 1 996 362,50"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["LoC"], "Technology_Description": "\u201cThe human imagination remains one of the last uncharted territories of the mind\u201d ", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["681404"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["KING'S COLLEGE LONDON"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Towards a typology of Visigothic script: the Beatus British Library Add. 11695 and its potential for dating and localising Visigothic script manuscripts"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ViGOTHIC"], "Technology_Description": "The main aim of the proposal is to establish a point of reference for the analysis of Visigothic script, the primary carrier of Latin writing in the Iberian Peninsula from the 8th to the 14th centuries. To date, most palaeographical analysis of Visigothic script has been conducted using a traditional methodology and following heterogeneous criteria, which has led to subjective results difficult to share or evaluate. In contrast, my research will create a computerised database of quantitative data by applying a specially designed method, a starting point that will allow codices written in Visigothic script to be described, compared and placed in their socio-cultural context. Innovative techniques for digital analysis of manuscript sources that will be acquired in the host institution will allow me to gain new insights into the analysis of the script while opening new avenues of research by applying digital tools to its study. The knowledge thus generated will be of great practical importance for future palaeographical and textual research establishing criteria upon which advanced studies can build. It will offer a means of understanding the script, its manuscripts, and its cultural context. ", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["656298"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN", "JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN"], "EU_Contribution": ["EUR 2 458 468"], "Project_Title": ["Cell-cell interactions at the neurovascular interface"], "Total_Cost": ["EUR 2 458 468"], "Country": ["Germany", "Germany"], "Project_ACR": ["NEUROVESSEL"], "Technology_Description": "The coordinated orchestration of cell movements is a vital process for assembling functional structures. In recent years we have learned a simplifying lesson: organ development is governed by a limited set of conserved cell-to-cell communication signaling pathways repeatedly used in different contexts. Particularly fascinating is the parallelism between the vascular and nervous systems. My lab has been working for more than a decade on the molecular and functional parallelism between nervous and vascular system development and plasticity. Although it is clear that cellular communication between the different cells in the brain is fundamental for brain function, very little is known about the signaling effectors that are used for such trans-cellular signaling. Molecular pathways involved in the crosstalk between vessels and neuronal cells are slowly emerging. How this crosstalk signaling is integrated at the interface of the different cellular players (neurons, endothelial cells, glial cells) for proper brain development and function is still poorly understood. Here I propose to delineate the molecular pathways that govern such communication in order to understand basic mechanisms of brain development, function and dysfunction. Using a combination of state-of-the-art inducible and cell type-specific genetics, both in mouse and zebrafish, together with high-resolution light microscopy and multi-photon live imaging we will examine the cell-context dependent integration of signaling pathways in building up proper neuronal/glial structures and functional networks. We will use advanced ultra-structural analysis using serial block-face electron microscopy (SBEM) to obtain high-resolution maps of cortical structures. Functionally, we will characterize the integration of vascular/glial/neuronal signals during cortical neuronal migration, arborization, synaptic connectivity, higher-order integrative cortical function and behavior-related plasticity in vivo.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["669742"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM", "UNIVERSITEIT VAN AMSTERDAM", "THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 1 497 270"], "Project_Title": ["The design and development of efficient biocatalytic cascades and biosynthetic pathways for the sustainable production of amines"], "Total_Cost": ["EUR 1 497 270"], "Country": ["Netherlands", "Netherlands", "United Kingdom"], "Project_ACR": ["BIOSUSAMIN"], "Technology_Description": "The objective of this project is to design and develop biocatalytic cascades, using purified enzymes in vitro, as well as biosynthetic pathways in whole cell microbial organisms. These biocatalytic cascades and biosynthetic pathways will be developed for the synthesis of chiral and achiral amines that are of particular interest for the chemical industry. The amine functionality will be introduced using amine dehydrogenases (AmDHs) as biocatalysts in the pivotal core enzymatic step. AmDHs are a new class of enzymes that have recently been obtained by protein engineering of wild-type amino acid dehydrogenases. However, only two AmDHs have been generated so far and, moreover, they show a limited substrate scope. Therefore protein engineering will be undertaken in order to expand the substrate scope of the already existing AmDHs. In addition, novel AmDHs will be generated starting from different wild-type amino acid dehydrogenases as scaffolds, whose amino acid and DNA sequences are available in databases, literature, libraries, etc. In particular, protein engineering will be focused on the specific chemical targets that are the objectives of the designed biocatalytic cascades and in addition, screening for more diverse substrates will also be carried out. Finally, the AmDHs will be used in combination with other enzymes such as alcohol dehydrogenases, oxidases, alkane monooxygenases, etc., to deliver variously functionalised amines and derivatives as final products with elevated yields, perfect chemo- regio- and stereoselectivity, enhanced atom efficiency and minimum environmental impact. Such an approach will be realised through the design of new pathways that will convert inexpensive starting materials from renewable resources, encompassing the internal recycling of redox equivalents, the use of inorganic ammonia as nitrogen source and, if necessary, only molecular oxygen as the innocuous additional oxidant. Water will be the sole by-product.", "To": ["2020-04-30, ongoing project |"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-05-01"], "Project_ID": ["638271"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["UNIVERSITY OF BRISTOL", "UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 1 873 483"], "Project_Title": ["Exponential sums, translation invariance, and applications"], "Total_Cost": ["EUR 1 873 483"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["ESTIA"], "Technology_Description": "Title: Exponential Sums, Translation Invariance, and Applications. ", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["695223"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM", "UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 1 405 652"], "Project_Title": ["Causal Analysis of Feedback Systems"], "Total_Cost": ["EUR 1 405 652"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["CAFES"], "Technology_Description": "Many questions in science, policy making and everyday life are of a causal nature: how would changing A influence B? Causal inference, a branch of statistics and machine learning, studies how cause-effect relationships can be discovered from data and how these can be used for making predictions in situations where a system has been perturbed by an external intervention. The ability to reliably make such causal predictions is of great value for practical applications in a variety of disciplines. Over the last two decades, remarkable progress has been made in the field. However, even though state-of-the-art causal inference algorithms work well on simulated data when all their assumptions are met, there is still a considerable gap between theory and practice. The goal of CAFES is to bridge that gap by developing theory and algorithms that will enable large-scale applications of causal inference in various challenging domains in science, industry and decision making. ", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["639466"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["UNIVERSITY OF BRISTOL", "UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 1 999 885"], "Project_Title": ["Isotope CYcling in the LABrador Sea"], "Total_Cost": ["EUR 1 999 885"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["ICY-LAB"], "Technology_Description": "The high-latitude regions are experiencing some of the most rapid changes observed in recent decades: polar temperatures are rising twice as fast as the global mean and there are concerns about the impact of sea-ice and glacier retreat on global oceans and climate. The high-latitude North Atlantic is also a key region for ecologically and economically important natural resources such as fisheries. How these resources will change in the future depends strongly on the response of marine biogeochemical cycling of essential nutrients to increasing anthropogenic stress.", "To": ["2021-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-07-01"], "Project_ID": ["678371"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM", "UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 1 499 909"], "Project_Title": ["Accurate simulations of strongly correlated systems with tensor network methods"], "Total_Cost": ["EUR 1 499 909"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["TENSORNETSIM"], "Technology_Description": "This project aims to achieve ground-breaking advances in the biggest challenge in computational condensed matter physics: the accurate simulation of strongly correlated systems (SCS), which give rise to fascinating phenomena such as high-Tc superconductivity (HTSC), quantum spin liquids with topological order, and other exotic phases of matter. While for one-dimensional (1D) systems tremendous progress has been made thanks to the famous density-matrix renormalization group (DMRG) method, in higher dimensions accurate methods have been lacking for many years. Recently, I achieved several major breakthroughs with tensor network methods, which can be seen as an extension of DMRG to higher dimensions. I was able to show that these methods outperform previous state-of-the-art approaches for several challenging models, making it clear that these methods will play a pivotal role in understanding SCS in 2D, in the same way as DMRG has revolutionized the study of 1D systems.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["677061"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM", "UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 1 499 999"], "Project_Title": ["The physics and forensics of neutron star explosions"], "Total_Cost": ["EUR 1 499 999"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["CSINEUTRONSTAR"], "Technology_Description": "Neutron stars offer a unique environment in which to develop and test theories of the strong force. Densities in neutron star cores can reach up to ten times the density of a normal atomic nucleus, and the stabilizing effect of gravitational confinement permits long-timescale weak interactions. This generates matter that is neutron-rich, and opens up the possibility of stable states of strange matter, something that can only exist in neutron stars. Strong force physics is encoded in the Equation of State (EOS), the pressure-density relation. This is linked to macroscopic observables such as mass M and radius R via the stellar structure equations. By measuring and inverting the M-R relation we can recover the EOS and diagnose the underlying dense matter physics.", "To": ["2020-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-06-01"], "Project_ID": ["639217"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["KING'S COLLEGE LONDON", "KING'S COLLEGE LONDON"], "EU_Contribution": ["EUR 2 499 817"], "Project_Title": ["Mitochondrial DNA degradation and sterile inflammation in the heart"], "Total_Cost": ["EUR 2 499 817"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["RAMBO"], "Technology_Description": "Heart failure is the leading cause of morbidity and mortality in developed countries including EU. Novel and efficient therapeutics to treat patient with heart failure have to be developed. Mitochondria are subcellular organelles that produce energy and dynamic organelles that fuse and divide. Dysregulated mitochondrial activity results in generation of free radicals which cause damage to cellular components. We reported that mitochondrial quality control by autophagy is essential for normal cardiac functions (Nat Med 2007). Mitochondrial DNA (mtDNA) contains bacteria-like unmethylated CpG motifs, which are inflammatogenic. We reported that mtDNA that escapes from autophagy-mediated degradation leads to inflammatory responses in cardiomyocytes and heart failure (Nature 2012). Damaged mitochondria in failing hearts are selectively removed by mitochondria-selective autophagy, mitophagy. Mitophagy is preceded by mitochondrial fission, which divides elongated mitochondria into pieces for autophagy. Although Atg32 is essential for mitophagy in yeast, no homologue has been known in mammals. Recently, we identified Bcl2-like protein 13 (Bcl2-L-13) as a functional mammalian homologue of Atg32 which induces mitochondrial fragmentation and mitophagy (Nat Commun in press) in mammalian cells. While methylation of nuclear DNA involves in epigenetic regulation of protein synthesis, the significance of mtDNA methylation in transcription and autophagy-medicated inflammation remains to be elucidated. Our pilot study showed an isoform of DNA methyltransferase targets to mitochondria for mtDNA methylation. In this proposal, we shall attempt to characterize regulation mechanism of Bcl2-L-13 and its in vivo function and to elucidate the physiological significance of mtDNA methylation. Furthermore, we shall elucidate the role of mtDNA methylation and Bcl2-L-13 in the genesis of heart failure and examine whether these will be the therapeutic targets for the treatment of heart failure.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["692659"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM", "UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 1 999 858"], "Project_Title": ["Finance/Security practice after 9/11: Following the Money from Transaction to Trial"], "Total_Cost": ["EUR 1 999 858"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["FOLLOW"], "Technology_Description": "The aim of FOLLOW is to understand and analyse the security practices that render financial transactions into security intelligence, into court evidence. The novel approach is to map the path of the suspicious financial transaction as a \u2018chain of translation.\u2019 I ask what gets lost and added in the process of translating financial records from banks to courts. I deliver fine-grained empirical analysis of four key elements \u2013 privacy challenges, knowledge practices, situated judgement, and effects \u2013 at each link in the chain: banks, Financial Intelligence Units (FIUs) and courts. I focus on four European Union member states that are most different cases: UK, Netherlands, Spain and Poland.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["682317"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM", "UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["At the roots of corruption: a behavioral ethics approach"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["Corruption Roots"], "Technology_Description": "For many years, human cooperation has been praised as beneficial in organizational and personal settings. Indeed, cooperation allows people to develop trust, build meaningful relationships, achieve mutually beneficial outcomes, and strengthen bonding with one's group members. However, while the benefits of cooperation are clear, very little is known about its possible negative aspects. Such negative aspects include the potential emergence of unethical conduct among cooperating partners, or as termed here \u2013 corrupt collaboration. Such joint unethical efforts, benefiting (directly or indirectly) one or more of the involved parties, occur in business, sports, and even academia. Corrupt collaboration emerges when one party bends ethical rules (here: lie) to set the stage for another party to further bend ethical rules and get the job done, that is, secure personal profit based on joint unethical acts. We propose that corrupt collaborations most commonly occur when all involved parties gain from the corrupt behavior. The current proposal is aimed at unfolding the roots and nature of corrupt collaborations; their existence, the psychological and biological processes underlying them, and the settings most likely to make corrupt collaboration emerge and spread. Accordingly, the information gathered in the current proposal has the potential to change the commonly held conceptions regarding the unidimensional \u2013 positive \u2013 nature of cooperation. It will help create a comprehensive understanding of cooperation and, specifically, when it should be encouraged or, alternatively, monitored.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["637915"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["UNIVERSITY OF BRISTOL", "UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 1 978 060"], "Project_Title": ["Quantum Photonic Engineering"], "Total_Cost": ["EUR 1 978 060"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["QPE"], "Technology_Description": "By harnessing the unique properties of quantum mechanics (superposition and entanglement) to encode, transmit and process information, quantum information science offers significant opportunities to revolutionise information and communication technologies. ", "To": ["2020-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-05-01"], "Project_ID": ["640079"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["UNIVERSITY OF BRISTOL", "UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 1 863 321"], "Project_Title": ["Effects of maternal gestational adiposity on fetal development and perinatal, postnatal and next generation health."], "Total_Cost": ["EUR 1 863 321"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["ObesityDevelop"], "Technology_Description": "Pregnant women who are overweight/obese have increased risks of adverse perinatal outcomes, and of having offspring who are subsequently overweight/obese. A potentially important consequence of this is that it will drive the obesity epidemic across generations. Evidence from animal models supports this, but it has not been explored in humans. Furthermore, we need to know the mechanisms linking maternal adiposity to adverse offspring and next generation outcomes in order to develop preventive interventions. ", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-11-01"], "Project_ID": ["669545"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["KING'S COLLEGE LONDON", "KING'S COLLEGE LONDON", "THE UNIVERSITY OF NOTTINGHAM", "THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN", "UNIVERSITY OF SOUTHAMPTON"], "EU_Contribution": ["EUR 3 394 214,88"], "Project_Title": ["Brain network based stratification of mental illness"], "Total_Cost": ["EUR 3 394 214,88"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom", "Ireland", "United Kingdom"], "Project_ACR": ["STRATIFY"], "Technology_Description": "To reduce the burden of mental disorders it is a formidable aim to identify widely applicable disease markers based on neural processes, which predict psychopathology and allow for targeted interventions. We will generate a neurobehavioural framework for stratification of psychopathology by characterising links between network properties of brain function and structure and reinforcement\u2013related behaviours, which are fundamental components of some of the most prevalent mental disorders, major depression, alcohol use disorder and ADHD. We will assess if network configurations define subtypes within and if they correspond to comorbidity across these diagnoses. We will identify discriminative data modalities and characterize predictors of future psychopathology.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["695313"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 258 107,40"], "Project_Title": ["Elaboration and degeneration of complex traits: The visual systems of lizards and snakes"], "Total_Cost": ["EUR 258 107,40"], "Country": ["United Kingdom"], "Project_ACR": ["Evol-Eyes"], "Technology_Description": "In \u201cOn the origin of species\u201d Charles Darwin used the human eye as an example of a complex character the evolution of which would have been hard to explain. Since then the vertebrate eye and the origin of vision more broadly held a central role in evolutionary biology. Recent advances in genomics, developmental biology and physiology, have allowed some advancement in our understanding of the origin of animal vision that however, is still patchy at best. Surprisingly, modern integrative studies have largely overlooked the visual systems of the Squamata (i.e. the lizards and snakes), a group comprising ~25% of terrestrial vertebrates, displaying exceptional diversity, and with greater variation in eye morphology and retinal photoreceptors than all other vertebrates combined. I propose to use the powerful but overlooked squamate system to answer major questions in visual science. I will integrate genomic, physiological and anatomical data to understand the genomic underpinning of phenotypic variation in the vertebrate visual system the relative roles of adaptation and constraints in the origin of novel visual phenotypes, and to understand whether complex visual systems can be re-elaborated following evolutionary degeneration. ", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["703438"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "UNIVERSITY OF BRISTOL", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 1 818 553"], "Project_Title": ["Search for a new form of matter: the sterile neutrino"], "Total_Cost": ["EUR 1 818 553"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom", "United Kingdom"], "Project_ACR": ["SOLID"], "Technology_Description": "The goal of this proposal is to search for an entirely new kind of matter. This type of matter called a sterile neutrino doesn\u2019t interact with known particles and can only manifest itself through quantum mixing with the three neutrinos of the standard model, the prevailing theory of particle physics. The known neutrinos are by far the most abundant massive particles in the Universe. More than 70 years after the postulation of the existence of the neutrino, its nature and fundamental properties remain, paradoxically, poorly known. The discovery of the quantum mixing of neutrinos: neutrino oscillations, was a major surprise as it implied that neutrinos have mass which they do not have in the standard model. In this context the existence of a sterile neutrino is a natural extension but the discovery of this new state of matter would a profound challenge for the theory to explain. Several new anomalous experimental results have appeared which could be accounted for by the presence of a light sterile neutrino but each result taken separately is not statistically significant. New oscillation patterns in the neutrino energy spectrum would be a clear signature of the new state but are difficult to measure due to experimental and background limitations. We propose the most sensitive search to date for this oscillation signature using two key assets:", "To": ["2021-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["682474"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM", "UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 1 918 306"], "Project_Title": ["Groups and Violence: A Micro-sociological Research Programme"], "Total_Cost": ["EUR 1 918 306"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["GROUPVIOLENCE"], "Technology_Description": "The Group Violence research programme aims to understand how group behaviour affects the likelihood and severity of violence in public space. While the prevailing social scientific focus remains on individual perpetrators and background factors, the empirical reality of public violence is one of multiple attackers, multiple victims and multiple bystanders. The research proposed here furthers the study of violence with a novel theory that identifies how group behaviour affects the outcome of antagonistic situations \u2013 and with comparative empirical studies to test the theory. The central question is how and to what extent 1) mutual alignment of attention and action, and 2) a sense of moral community enable group members to commit violence. Project 1 (PI and post-doc) considers mutual alignment down to the minutest detail, based on close-up qualitative and quantitative video analyses of sequences of bodily cues. Based on judicial case files, project 2 (PI and assistants) will quantitatively analyse mutual alignment in an extensive range of violent interactions. Four PhD projects compare the role of mutual alignment and moral community in antagonistic situations in groups that differ from each other in these respects: police teams (project 3), street youth (4), football hooligans (5), and bouncers (6). Relying on an innovative method to reconstruct antagonistic situations by repeated and comparative qualitative interviewing, projects 3-6 will also relate the meanings of violence and masculine identity to the moral community of the group. Project 7 (PI and post-doc) uses qualitative and statistical analyses of the interview data generated in projects 3-6 for an extensive comparison of group behaviour in antagonistic situations. The ambition is to produce exemplary understanding of the crucial role that groups play in violence. This proposal shows how: through detailed and extensive comparative empirical testing that will further develop the new theory.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["683133"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["UNIVERSITY OF BRISTOL", "UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 1 971 866"], "Project_Title": ["Consequences of out-group conflict"], "Total_Cost": ["EUR 1 971 866"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["Outgroup"], "Technology_Description": "The aim of this project is to determine the proximate and ultimate consequences of a fundamental but neglected aspect of sociality: out-group conflict. In a wide range of social species, from ants to humans, group members invest considerable defensive effort against individual intruders and rival groups. The lasting impacts of these conflicts with conspecifics are poorly understood. I will integrate empirical and theoretical approaches to uncover the effect of out-group conflict on: (i) individual behaviour, within-group interactions and group decision-making; (ii) steroid hormones that underlie stress, social behaviour and reproduction; (iii) variation in reproductive success arising from maternal investment and offspring care; and (iv) the evolution of societal structure, cooperation and punishment among group-mates, and weaponry and fortification. I will achieve these ambitious objectives using proven experimental paradigms, innovative non-invasive sampling, long-term monitoring, and state-of-the-art analytical methods to collect data from two highly tractable model systems that I have established over the last 4 years: a captive-breeding population of the cichlid fish Neolamprologus pulcher and a habituated wild population of dwarf mongooses (Helogale parvula). I will use some of the same data to inform the assumptions of mathematical models and evolutionary simulations in the development of a rigorous, predictive framework on out-group conflict, which I will test using both my model systems and phylogenetically controlled meta-analyses across species. The management and consequences of conflict are of major importance to science, human society and global politics. My novel and inter-disciplinary proposal will not only significantly advance our understanding of the evolution of sociality, but will invigorate a variety of existing research programmes across biology, anthropology, economics, psychology, and the social and political sciences.", "To": ["2021-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-07-01"], "Project_ID": ["682253"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["UNIVERSITY OF BRISTOL", "UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 1 467 038"], "Project_Title": ["Comparative Analysis of Social Spaces in Post-Industrial Nations"], "Total_Cost": ["EUR 1 467 038"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["CASSPIN"], "Technology_Description": "The proposed research has two overarching objectives. First, it aims to examine whether it is possible and appropriate to extend a novel way of measuring social class recently devised for the United Kingdom to other post-industrial nations for the purposes of cross-national comparative research. If it is, the project will begin to explore, through secondary and primary analysis of large-scale survey data, the different shapes and trajectories of the class structures \u2013 or \u2018social spaces\u2019 \u2013 of various nation states. This will involve examination of which classes and sub-classes predominate and which have emerged or declined, as well as the different gender and ethnic/nationality constitutions of the classes and the distinct effects these differences have for understanding cultural and political struggles and, ultimately, the distribution of power or \u2018recognition\u2019 in each country. Second, the project aims to explore, through both statistical analysis and qualitative interviews, how social class is actually lived, experienced and balanced against other pressures and sources of recognition in everyday life, with a focus on three specific nations: the United States, Germany and Sweden. Of particular interest in this respect is the balancing of desire for recognition through money and education \u2013 the two cornerstones of social class in post-industrial capitalist societies \u2013 and their associated lifestyles with desires for recognition and love within the family. The comparative analysis included in both research aims will be guided by the hypothesis that national differences depend on the nature of the welfare regime in operation, especially as it relates to the nature and extent of workforce feminisation, though the research will also be alive to the possibility of alternative \u2013 or no significant \u2013 sources of contrast.", "To": ["2021-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["677055"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN", "JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN"], "EU_Contribution": ["EUR 2 497 398"], "Project_Title": ["Endothelial long non-coding RNAs"], "Total_Cost": ["EUR 2 497 398"], "Country": ["Germany", "Germany"], "Project_ACR": ["Angiolnc"], "Technology_Description": "Endothelial cells comprise the inner cellular cover of the vasculature, which delivers metabolites and oxygen to the tissue. Dysfunction of endothelial cells as it occurs during aging or metabolic syndromes can result in atherosclerosis, which can lead to myocardial infarction or stroke, whereas pathological angiogenesis contributes to tumor growth and diabetic retinopathy. Thus, endothelial cells play central roles in pathophysiological processes of many diseases including cardiovascular diseases and cancer. Many studies explored the regulation of endothelial cell functions by growth factors, but the impact of epigenetic mechanisms and particularly the role of novel non-coding RNAs is largely unknown. More than 70 % of the human genome encodes for non-coding RNAs (ncRNAs) and increasing evidence suggests that a significant portion of these ncRNAs are functionally active as RNA molecules. Angiolnc aims to explore the function of long ncRNAs (lncRNAs) and particular circular RNAs (circRNAs) in the endothelium. LncRNAs comprise a heterogenic class of RNAs with a length of > 200 nucleotides and circRNAs are generated by back splicing.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["667255"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM", "UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 1 256 624"], "Project_Title": ["Moonshine and String Theory"], "Total_Cost": ["EUR 1 256 624"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["MST"], "Technology_Description": "The purpose of the proposed research is to forward the understanding of the umbral moonshine discovered recently by myself. I plan to study it in the context of string theory. Moreover, I aim to use this new discovery to gain a deeper understanding of certain fundamental aspects of the theory. ", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["640159"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM", "UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 1 959 690"], "Project_Title": ["Psychosystems:Consolidating Network Approaches to Psychopathology"], "Total_Cost": ["EUR 1 959 690"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["Psychosystems"], "Technology_Description": "I have recently introduced the Network Approach to Psychopathology. This approach is based on the interpretation of mental disorders as causal systems. Such systems have two basic building blocks: symptoms (i.e., problems like insomnia, fatigue, and concentration problems) and connections between symptoms (i.e., causal and homeostatic relations, such as insomnia \u2192 fatigue \u2192 concentration problems). Together, these building blocks constitute a network, which can be analyzed as a complex system. I have successfully used this approach to explain important phenomena in psychopathology research, such as comorbidity, spontaneous recovery, and prevalence differences between disorders. In addition, I have invented techniques to identify dynamic network structures from time series data, as obtained through experience sampling methodology. This proposal consolidates the Network Approach to Psychopathology through (a) further development and testing of methodologies, and (b) applications of the model to important research domains in clinical psychology. The project is structured in two postdoc projects and two Ph. D. projects. Postdoc project Network estimation and control develops analysis techniques for the estimation of large symptom networks. Postdoc project Early warning signals and transitions investigates whether transitions in symptom networks can be predicted using early warning signals, such as critical slowing down. Ph. D. project Resilience and vulnerability tests the hypothesis that more strongly connected networks are more vulnerable to disorders and investigates whether depressive episodes lead to prolonged changes in network structure. Ph. D. project The dark matter of psychopathology investigates the role of \"anti-symptoms\" \u2013 networks of positive factors that have buffering effects on symptom networks. This new approach to the study of psychopathology aims to establish a breakthrough in the understanding of mental disorders.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["647209"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["KING'S COLLEGE LONDON", "KING'S COLLEGE LONDON"], "EU_Contribution": ["EUR 2 274 225"], "Project_Title": ["The values of French language and literature in the European Middle Ages"], "Total_Cost": ["EUR 2 274 225"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["TVOF"], "Technology_Description": "Two questions about linguistic identity lie at the heart of this project. What is the relation historically between language and identity in Europe? How are cognate languages demarcated from each other? Normative models of national languages helped shape Europe. Yet they did not become hegemonic until the 19th century. Indeed, they were imposed (not always successfully) on a linguistic map of Europe more fluid and complex than most histories of national languages allow. In the Middle Ages multilingualism was common, as was the use of non-local languages, notably Latin, but also French. This project undertakes a revaluation of the nature and value of the use of French in Europe during a crucial period, 1100-1450, less in terms of its cultural prestige (the traditional focus of scholarship) than of its role as a supralocal, transnational language, particularly in Western Europe and the Eastern Mediterranean. The project fosters collaboration between, and cuts across, different intellectual and national scholarly traditions, drawing on expertise in codicology, critical theory, linguistics, literature, and philology; it involves scholars from a range of European countries and North America, entailing empirical research around a complex and widely disseminated textual tradition vital to medieval understandings of European history and identity, L\u2019Histoire ancienne jusqu\u2019\u00e0 C\u00e9sar. This case study will ground and stimulate broader speculative reflection on the two core questions concerning linguistic identity. While the project builds on prior critiques of the construction of, and investment in, national languages and literary traditions, it has a broad historical scope, and will offer an innovative, genuinely international perspective, in terms of both its object of study and method. Indeed, its final aim, through and beyond its consideration of French as a lingua franca, is to interrogate that language\u2019s role in the emergence of a European identity in the Middle Ages.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["670726"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["UNIVERSITY OF BRISTOL", "UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 2 397 430"], "Project_Title": ["Global land ice, hydrology and ocean mass trends"], "Total_Cost": ["EUR 2 397 430"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["GlobalMass"], "Technology_Description": "Sea level rise will be one of the most serious and costly consequences of future climate change. Constraining the sources and sinks of sea level change is essential for understanding the drivers of past variations and for improving predictions of future behaviour. Matching estimates of sea level rise with the components that affect it is a long standing problem in geosciences spanning multiple disciplines: oceanography, glaciology, hydrology and solid Earth physics. Traditionally, each part of the problem has been tackled separately using different data, techniques and physical understanding. This is because of the challenge in determining just one component but also because of the different expertise and understanding within the various communities. The proposed research will, for the first time, tackle all components simultaneously. I will combine all the relevant observations (both from satellites and in situ) with physical principles of the coupled system to solve for all components of the sea level budget. First, I will produce a data-driven estimate for glacio-isostatic adjustment that is independent of any assumptions about Earth structure or ice loading history. Second, I will partition the sea level budget into its steric, hydrological, cryospheric and solid earth components for 1981-2020. Third, I will apply the methods and datasets to re-evaluate the 20th Century sea level record. These advances will also result in the determination of regional mass trends of land ice and hydrology over a ~30 year period. In the process of attaining these goals in geosciences, I will also develop state of the art techniques for statistical inference of Big Data. I have developed and tested the approach, using a subset of the data, for the Antarctic ice sheet. The approach is unique, global in scale and will address fundamental problems across four different disciplines in geosciences, as well as advancing techniques in statistical inference and computer science.", "To": ["2021-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-08-01"], "Project_ID": ["694188"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["TECHNISCHE UNIVERSITEIT EINDHOVEN", "TECHNISCHE UNIVERSITAT DARMSTADT", "UNIVERSIDAD CARLOS III DE MADRID", "JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN", "AALTO-KORKEAKOULUSAATIO", "VYSOKE UCENI TECHNICKE V BRNE", "POLITECHNIKA WARSZAWSKA", "UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA", "CESKE VYSOKE UCENI TECHNICKE V PRAZE", "UNIVERSITA DEGLI STUDI DELL'AQUILA", "UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN", "KUNGLIGA TEKNISKA HOEGSKOLAN", "DANMARKS TEKNISKE UNIVERSITET"], "EU_Contribution": ["EUR 3 785 419,68"], "Project_Title": ["Convergence of Electronics and Photonics Technologies for Enabling Terahertz Applications"], "Total_Cost": ["EUR 3 785 419,68"], "Country": ["Netherlands", "Germany", "Spain", "Germany", "Finland", "Czech Republic", "Poland", "Italy", "Czech Republic", "Italy", "Ireland", "Sweden", "Denmark"], "Project_ACR": ["CELTA"], "Technology_Description": "CELTA: Convergence of Electronics and Photonics Technologies for Enabling Terahertz Applications aims to produce the next generation of researchers who will enable Europe to take a leading role in the multidisciplinary area of utilizing Terahertz technology for applications involving components and complete systems for sensing, instrumentation, imaging, spectroscopy, and communications. All these technologies are key to tackle important solutions in a large number of focus areas relevant for the societal challenges identified in the Horizon2020 work programme. To achieve this objective, CELTA is comprised of eleven leading research institutions and assembled a comprehensive research training programme for all the fifteen early stage researchers (ESRs). CELTA integrates multidisciplinary scientific expertise, complementary skills, and experience working in academia and industry to empower ESRs to work in interdisciplinary teams, integrate their activities, share expertise, and promote a vision of a converged co-design and common engineering language between electronics and photonics for Terahertz technologies. Therefore, CELTA will introduce the strategy of converged electronics and photonics co-design in its research program and makes a special effort on establishing a common engineering language in its training program across the electronics, photonics and applications disciplines. We believe this common engineering language and converged co-design is mandatory to make the next logical step towards efficient and innovation solutions that can reach the market. The detailed compendium of lectures on state-of-the art technology, soft skills and entrepreneurship is accompanied by a research programme that focuses on THz key technologies. CELTA ESRs will develop three demonstrators: beam steering technology for communication applications, a photonic vector analyser for spectroscopy and materials characterization, and a THz imager for sensing applications.", "To": ["2020-02-29, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Jiri Matas", "Tel.: +420 22435721", "Fax: +420 224357385", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["675683"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["UNIVERSITY OF PORTSMOUTH HIGHER EDUCATION CORPORATION"], "EU_Contribution": ["EUR 250 104,60"], "Project_Title": ["Students, social change and the construction of the post-independence Algerian state, 1962-1978"], "Total_Cost": ["EUR 250 104,60"], "Country": ["United Kingdom"], "Project_ACR": ["STUSOCSTA"], "Technology_Description": "This project seeks to bring a new perspective to understanding state construction in Algeria after independence. Through a history of the first generations of Algerians who went to university in the 1960s and 1970s, it explores the intersections between political and institutional transformations and social, cultural and economic processes. These processes include increasing literacy, rural to urban migration, migration to study abroad and changes in gender relations and family structures. Bringing together concepts and methodologies from across a number of humanities and social science disciplines, the project will produce a case study setting out new approaches to studying state-building as a dynamic process which takes place at different levels of power (transnational, national and local) and which both shapes, and is shaped by, individual agency and wider processes. The goal is for this approach to be applicable to a range of other post-colonial contexts, challenging teleological readings of post-independence histories and homogenising understandings of post-independence states. ", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["705763"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM", "UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 1 391 324"], "Project_Title": ["Quantification and modality in the realm of questions"], "Total_Cost": ["EUR 1 391 324"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["QuModQu"], "Technology_Description": "The interpretation of linguistic expressions has been investigated from various theoretical perspectives, ranging from linguistics and philosophy to logic and cognitive science, leading to many applications in computer science. At the heart of this enterprise is a simple yet powerful notion of meaning as truth-conditional content. Despite its merits, this view has a fundamental limitation: while suitable for statements, it does not apply to other sentence types, like questions.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["680220"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "STICHTING VU", "UNIVERSITA DEGLI STUDI DI VERONA", "WAGENINGEN UNIVERSITY", "UNIVERZITA PALACKEHO V OLOMOUCI", "QUEEN MARY UNIVERSITY OF LONDON", "TURUN YLIOPISTO", "PHOTON SYSTEMS INSTRUMENTS SPOL SRO", "PHYCOSOURCE SARL", "UMEA UNIVERSITET", "RIJKSUNIVERSITEIT GRONINGEN"], "EU_Contribution": ["EUR 3 866 945,22"], "Project_Title": ["Solar Energy to Biomass - Optimisation of light energy conversion in plants and microalgae"], "Total_Cost": ["EUR 3 866 945,22"], "Country": ["Germany", "France", "Netherlands", "Italy", "Netherlands", "Czech Republic", "United Kingdom", "Finland", "Czech Republic", "France", "Sweden", "Netherlands"], "Project_ACR": ["SE2B"], "Technology_Description": "In the face of the increasing global consumption of fossil resources, photosynthetic organisms offer an attractive alternative that could meet our rising future needs as clean, renewable, sources of energy and for the production of fine chemicals. Key to the efficient exploitation of these organisms is to optimise the conversion of Solar Energy into Biomass (SE2B). The SE2B network deals with this optimisation in an interdisciplinary approach including molecular biology, biochemistry, biophysics and biotechnology. Regulation processes at the level of the photosynthetic membranes, integrating molecular processes within individual proteins up to flexible re-arrangements of the membranes, will be analysed as a dynamic network of interacting regulations. SE2B will yield information about the similarities and differences between cyanobacteria, green algae, diatoms and higher plants, the organisms most commonly employed in biotechnological approaches exploiting photosynthetic organisms, as well as in agriculture. ", "To": ["2020-02-29, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["675006"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM", "UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 2 499 780"], "Project_Title": ["Separation Technology for A Million Peaks"], "Total_Cost": ["EUR 2 499 780"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["STAMP"], "Technology_Description": "Extremely high separation powers are required to fully characterize complex mixtures that are of crucial importance in many fields, such as life science (including systems biology), food science, renewable energy sources and feedstocks, and high-tech materials. The STAMP project is aimed at obtaining a peak capacity of one million in liquid-phase analytical separations. Spatial three-dimensional liquid chromatography will be used to achieve this goal. The major advantage of this technique is that all second-dimension separations and \u2013 in a next step \u2013 all third-dimension separations are performed in parallel. This allows high-resolution separations to be performed in each dimension, while the total analysis time remains reasonable. Optical and mass-spectrometric imaging techniques are envisaged as detection methods after printing (STAMPing) the effluent from the 3D separation body on a suitable substrate. The STAMP project also has a number of sub-targets that will bring additional significant benefits to all the above application fields. ", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["694151"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET", "INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE", "UPPSALA UNIVERSITET", "UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA", "JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN", "EUROPEAN MOLECULAR BIOLOGY LABORATORY", "CENTRE EUROPEEN DE RECHERCHE EN BIOLOGIE ET MEDECINE", "INSTITUT PASTEUR", "SYSTASY BIOSCIENCE GMBH", "Novo Nordisk A/S"], "EU_Contribution": ["EUR 3 744 859,32"], "Project_Title": ["Unraveling Principles of PDZ-mediated Cell Signaling"], "Total_Cost": ["EUR 3 744 859,32"], "Country": ["Denmark", "France", "Sweden", "Italy", "Germany", "Germany", "France", "France", "Germany", "Denmark"], "Project_ACR": ["PDZnet"], "Technology_Description": "PDZnet will create an innovative European PhD training network focusing on unraveling PDZ domain-mediated signaling networks. The emphasis will be on signaling nodes essential for the development of cancer and diseases of the nervous system, conditions that affect millions of Europeans and are major societal challenges. PDZ domains are protein and lipid recognizing modules that play a central role in trafficking and organizing diverse cell signaling assemblies, thereby allowing information to be transmitted from receptors, ion channels and transporters in the cell membrane. PDZ domain mediated interactions are emerging as conceptually novel and promising drug targets, with exciting opportunities for the development of novel therapies, especially within cancer and brain diseases. We will establish a European multidisciplinary platform integrating a plethora of complementary life science disciplines that range from chemical development of inhibitors to studies in live animals. The network encompasses 8 academic and 2 industrial beneficiaries as well as one industrial and one academic partner, which are all committed to promote frontline research, innovation and educational activities within the study of PDZ domain-mediated signal transduction pathways related to brain diseases and cancer. This interdisciplinary network will establish an outstanding training opportunity for Early Stage Researchers, who will be integrated in projects unraveling intracellular PDZ domain interactomes to provide pertinent information for discovering drug-related interactions. In a comprehensive and integrated training effort, involving a combination of scientific and transferable skills, the students will receive an interdisciplinary, intersectoral and innovative doctoral training from experienced industrial and academic leaders in well-reputed European Institutions.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-09-01"], "Project_ID": ["675341"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["UNIVERSITAT ZURICH", "UNIVERSITAT DES SAARLANDES", "UNIVERSITY OF BRISTOL", "UNIVERSITA DEGLI STUDI DI PAVIA", "Stichting Sanquin Bloedvoorziening", "UNIVERSITAIR MEDISCH CENTRUM UTRECHT", "CONSORCI INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER", "INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "ARIVIS AG", "EPIGEM LIMITED", "Nanion Technologies GmbH", "OPTOROBOTIX APS", "Fundaci\u00f3 Institut de Recerca Contra la Leucemia Josep Carreras"], "EU_Contribution": ["EUR 3 896 558,64"], "Project_Title": ["Regulation of red cell life-span, erythropoiesis, survival, senescence and clearance"], "Total_Cost": ["EUR 3 896 558,64"], "Country": ["Switzerland", "Germany", "United Kingdom", "Italy", "Netherlands", "Netherlands", "Spain", "France", "France", "Germany", "United Kingdom", "Germany", "Denmark", "Spain"], "Project_ACR": ["RELEVANCE"], "Technology_Description": "Anaemia is the most common pathological condition affecting 1.6 billion individuals worldwide. It thus presents a serious health care problem and an economic burden. Reduction in red blood cell (RBC) number can be caused by blood loss, diet, stress conditions including endurance sport, and pathologies which are caused by primary genetic aberrations or are secondary to the malfunction of other cell types. Transfusion of RBC, which is often the only cure for severe cases of anaemia, is associated with risks such as thrombosis and transfusion reactions due to allo-immunisation. There is an unmet need to improve treatment of anaemia through early and accurate diagnosis, targeted treatment, and increased safety and effectiveness of RBC transfusion. The aim of RELEVANCE is to improve fast and cost-effective diagnosis of the underlying cause of primary anaemia, and to improve treatment options for both general and personalised medicine. We defined five key objectives: (1) to improve diagnostics of anaemia, particularly for hereditary rare forms of anaemia (RA); (2) to find novel treatments for anaemia that target RBC production, ageing and clearance; (3) to reduce premature loss of RBC following transfusion; (4) to produce cultured RBC for transfusion; (5) to monitor and optimise RBC function during sport and exercise. RELEVANCE will train 15 early stage researchers (ESR) at four SMEs and eight academic partners, two of whom are at blood supply centres and two are diagnostic centres for RA. The continuous interactions between the clinic, blood supply centers, basic research, and industry will select for the most relevant unmet medical needs, and will stimulate innovative procedures that are immediately probed for applicability and validity both in a research and a clinical setting. RELEVANCE will organize three open access summer schools, extending training beyond the ESR of the ITN sustaining the critical number of young talented professionals in the field.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Corinna Hahn", "Tel.: +49 681 95 92 3362", "Fax: +49 681 95 92 3370", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations"], "From": ["2015-09-01"], "Project_ID": ["675115"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Main group chemistry, inorganic polymers, catalysis, silicon- and phosphorus-based polymers"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["LWIMT"], "Technology_Description": "Inorganic polymers are of widespread interest as a result of their useful combination of physical and chemical properties, which offer exciting opportunities for their use as advanced materials for many different applications. In the proposed research state-of-the-art strategies worked out in organic catalysis will be applied for the first time to main group substrates to form main group element-element (specifically Si\u2013O and PV\u2013O) bonds, targeting efficient new routes to inorganic polymers that involve mild reaction conditions and permit microstructure control. Once formed, the new polymeric materials will be characterized in detail and potential applications explored. To achieve these objectives Dr. Lipeng Wu, an exceptionally talented young scientist from China who performed his Ph.D. and postdoc in top organic catalysis groups in Germany (Matthias Beller, Rostock) and the USA (F. Dean Toste, UC Berkeley), will work in the internationally leading research group of Prof. Ian Manners (Bristol, UK) with expertise in catalysis with main group substrates, inorganic polymers, and polymer materials science. Armed with the new knowledge and experience gained, following the fellowship Dr. Wu aims to obtain an academic position in China where catalysis with main group compounds and inorganic polymers play a key role.", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["701972"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE UNIVERSITY OF NOTTINGHAM", "ROENTDEK - HANDELS GMBH", "JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN", "PHOTEK LIMITED", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "AARHUS UNIVERSITET", "CONSIGLIO NAZIONALE DELLE RICERCHE", "FORSCHUNGSVERBUND BERLIN EV", "Soci\u00e9t\u00e9 civile SYNCHROTRON SOLEIL"], "EU_Contribution": ["EUR 3 180 705,84"], "Project_Title": ["Angular studies of photoelectrons in innovative research environments"], "Total_Cost": ["EUR 3 180 705,84"], "Country": ["United Kingdom", "Germany", "Germany", "United Kingdom", "France", "Denmark", "Italy", "Germany", "France"], "Project_ACR": ["ASPIRE"], "Technology_Description": "In the ASPIRE project, whose academic and industrial beneficiaries are world leading in their complementary fields of expertise, the overarching research goal is the measurement of photoelectron angular distributions (PADs) in the \u201cmolecular frame\u201d (MF) of systems of biological relevance. These MF-PADs can be interpreted as electron diffraction patterns, achieved by \u201cilluminating the molecule from within\u201d, and enable the shapes and motions of individual molecules to be interrogated. Such knowledge is needed for the development of new medicines (the shapes of drug molecules dictate their function) and new materials (efficient solar cells can be constructed if energy dissipation processes in molecules are understood). Progress in this area is highly technologically driven, requiring high repetition rate, short wavelength light sources and fast detectors. The input of private sector beneficiaries is therefore critical to the scientific objectives, as well as to the enhanced training environment. Work packages on advanced light source and detector developments will feed into the overall goal through secondments, regular virtual meetings and face-to-face network meetings. The symbiosis of the developments that will take place in ASPIRE will create a research and training environment that is world-leading and optimally tailored to capitalise, for example, on the investment that has been made in the European XFEL facility. The ESRs will be trained in world-leading laboratories and will benefit from the exchange of best practice among beneficiaries and partners, and from unique training events. ASPIRE will therefore ensure that European research remains competitive in the global market, and that the trained researchers will be uniquely well-placed to contribute to the development of novel instrumentation in the future.", "To": ["2020-02-29, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations"], "From": ["2016-03-01"], "Project_ID": ["674960"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["UNIVERSITY OF BRISTOL", "UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 2 436 379"], "Project_Title": ["Efficient, Flexible Synthesis of Molecules with Tailored Shapes: from Photo-switchable Helices to anti-Cancer Compounds"], "Total_Cost": ["EUR 2 436 379"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["FRESCO"], "Technology_Description": "The creation of new molecular entities and subsequent exploitation of their properties is central to a broad spectrum of research disciplines from medicine to materials but progress has been limited by the difficulties associated with chemical synthesis. We are now proposing a fundamentally new strategy, which has the potential to revolutionise how we conduct complex organic synthesis. The basic C\u2013C bond-forming step involves the reaction of a lithiated carbamate with a boronic ester to give a homologated boronic ester with complete stereocontrol. Furthermore, the reaction shows >98% efficiency in most cases and can be conducted iteratively and in one pot (up to 9 iterations has been demonstrated with full stereocontrol). We will now extend this methodology to more functionalised carbamates as this will enable the rapid synthesis of polypropionates, which are amongst the most important classes of biologically active molecules. The robust methodology is now ripe for transfer to the solid phase as this will enable the preparation of libraries of these molecules. Through applying our assembly-line-synthesis methodology to complex molecules with diverse structures, we will demonstrate its scope, robustness, and full potential. The methodology enables stereochemistry to be \u2018dialled in\u2019 to a carbon chain, which in turn controls the conformation and we will exploit this feature in the shape-selective synthesis of molecules. We will explore how the sense of helical chirality of these molecules can be switched (M to P) just with light. We will target helical molecules with specific groups at specific places for optimum binding to disrupt protein\u2013protein interactions involved in cancer. Finally, our methodology provides ready access to a family of building blocks that represent common repeat units found in polyketides. By combining these building blocks iteratively using lithiation-borylation, we should be able to rapidly and reliably prepare complex natural products.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["670668"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["KING'S COLLEGE LONDON"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["The involvement of epidermal stem cells in spatiotemporal ERK activity propagation"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SKINFRET"], "Technology_Description": "Stem cells are central to maintenance of mammalian epidermis. This proposal focuses on how stem cells communicate with their microenvironment by intercellular propagation of growth signal. I will investigate the involvement of epidermal stem cells in a novel growth signal propagation pattern I found in my PhD research. In this research, I visualized extracellular signal regulated kinase (ERK) activity in the skin of living mice by FRET-based observation of transgenic mouse expressing a sensitive biosensor for ERK. By this approach, I found a novel pattern of intercellular ERK activity propagation, which we named SPREAD. In SPREAD, bursts of localized ERK activation concentrically propagated to their surrounding 100 -300 cells. The timing and location of SPREAD emergence suggested the involvement of epidermal stem cells. To test this possibility I will combine my expertise of FRET imaging with in vivo and in vitro systems for mouse and human keratinocytes in the host laboratory. By crossing ERK biosensor mice with various mouse strains that marks Lgr5+, Lgr6+, or Lrig1+ stem cells, I will observe whether the centre cells of SPREADs are epidermal stem cells in vivo. In addition, I will culture keratinocytes expressing the ERK FRET biosensor on an artificially engineered substrate to recapitulate SPREAD in vitro. To study whether SPREADs are also seen in human skin, I will exploit a skin reconstruction system, called organotopic culture. The method allows culture of keratinocytes on collagen matrices embedded with various fibroblast populations with various densities. The significance of the features of SPREAD (shape, size, amplitude etc.) will be addressed by generating various types of ERK activity propagation by using light-induced ERK activation system. This approach will bring fresh insights into how stem cells control their local tissue structures via intercellular propagation of growth signal and how microenviromental factors effect on the propagation pattern.", "To": ["2018-06-26, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-06-27"], "Project_ID": ["704587"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITAT KONSTANZ", "UNIVERSITAT KONSTANZ", "UNIVERSITAET STUTTGART"], "EU_Contribution": ["EUR 2 036 750"], "Project_Title": ["Active Suspensions with Controlled Interaction Rules"], "Total_Cost": ["EUR 2 036 750"], "Country": ["Germany", "Germany", "Germany"], "Project_ACR": ["ASCIR"], "Technology_Description": "Self-propelling, i.e., active colloidal particles constitute a novel class of non-equilibrium systems which exhibit structural and dynamical features similar to those in assemblies of bacteria or other motile organisms. Due to their reduced complexity, they provide an intriguing chance to understand the formation of dynamical structures in non-equilibrium systems in unprecedented detail. A central question in this rapidly growing field is, how interaction-rules determine the creation of e.g. swarms or complex networks. In addition to ordinary inter particle and hydrodynamic forces, interaction-rules can be much more complex. For example, they can regulate the particle motility depending on their relative orientation, their local density or otherwise distinct particle configurations.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["693683"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["UNIVERSITY OF BRISTOL", "ECOLE CENTRALE DE LYON", "UNIVERSITY OF NORTHUMBRIA AT NEWCASTLE", "UNIVERSITAET INNSBRUCK", "HELMHOLTZ ZENTRUM POTSDAM DEUTSCHESGEOFORSCHUNGSZENTRUM GFZ", "EIDGENOESSISCHE FORSCHUNGSANSTALT WSL", "MBIOINFORM APS", "UNIVERZA V LJUBLJANI", "INSTITUTUL DE BIOLOGIE BUCURESTI", "HASKOLINN A AKUREYRI", "ENOVEO SARL", "ABERYSTWYTH UNIVERSITY", "DR. BRILL + PARTNER GMBH INSTITUT FUER HYGIENE UND MIKROBIOLOGIE"], "EU_Contribution": ["EUR 3 897 006,48"], "Project_Title": ["Microorganisms in Warming Arctic Environments"], "Total_Cost": ["EUR 3 897 006,48"], "Country": ["United Kingdom", "France", "United Kingdom", "Austria", "Germany", "Switzerland", "Denmark", "Slovenia", "Romania", "Iceland", "France", "United Kingdom", "Germany"], "Project_ACR": ["MicroArctic"], "Technology_Description": "The Arctic plays a key role in the Earth\u2019s climate system and is an area of growing strategic importance for European policy. In this ETN, we will train the next generation of Arctic microbiology and biogeochemistry experts who, through their unique understanding of the Arctic environment and the factors that impact ecosystem and organism response to the warming Arctic, will be able to respond to the need for leadership from public, policy and commercial interests. The training and research programme of MicroArctic is made up of seven interlinked Work Packages (WP). WP1 to WP4 are research work packages at the cutting edge of Arctic microbiology and biogeochemistry and these will be supported by three overarching WPs (WP5-7) associated with the management, training and dissemination of results. WP1 will deliver information about the role of external inputs (e.g., atmospheric) of nutrients and microorganism that drive biogeochemical processes in relation to annual variation in Arctic microbial activity and biogeochemical processes. WP2 will explore ecosystem response on time scales of 100s of years to these inputs using a chrnosequence approach in the already changing Arctic. The effect of time and season and the warming of the Arctic on ecosystem functioning and natural resources will be quantified through geochemical analyses and next generation multi-omics approaches. Complementing WP1 and WP2, WP3 will focus on organism response and adaptation using a range of biochemical, molecular, experimental and culturing approaches. WP4 will address specific applied issues such as colonisation by pathogenic organisms and biotechnological exploitation of Arctic ecosystems. MicroArctic will bring together interdisciplinary experts from both the academic and non-academic sectors across Europe into a network of 20 Institutions across 11 countries.", "To": ["2020-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-04-01"], "Project_ID": ["675546"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 162 864,60"], "Project_Title": ["Unconditional parental regard: Its nature and its consequences"], "Total_Cost": ["EUR 162 864,60"], "Country": ["Netherlands"], "Project_ACR": ["UPR"], "Technology_Description": "Unconditional parental regard refers to parents accepting children for who they are, even when they disapprove of children\u2019s achievements (e.g., school grades). Psychological theory holds that children internalize unconditional regard to feel worthy for who they are. Children may thus feel less pressured to excel, and become more intrinsically motivated and less afraid of failure. However, unconditional regard has received little empirical scrutiny. The main objectives of this 24-month Marie Curie IF-GF are (a) to investigate the nature and consequences of unconditional parental regard in childhood; (b) to provide advanced training in experimental research (pioneered by the partner organization) and intervention development (pioneered by the beneficiary); and (c) to provide advanced training in soft skills and entrepreneurial skills. Thus, it brings the applicant closer to mid-term career goals of becoming a leading expert and establishing a research group in the field of socialization\u2014a field where the EU currently lags behind the US. In this project, one study explores how parents express unconditional regard (Study 1). Two experiments investigate the causal effects of unconditional regard on children\u2019s self-worth and motivation (Study 2-3). An observational-longitudinal study investigates whether the effects of unconditional regard sustain over time in children\u2019s lives (Study 4). The studies will be conducted in specialized laboratories under supervision of leading experts. The project strengthens the EU\u2019s position in the field of socialization, and establishes a long-term cross-disciplinary collaboration between the applicant and participating parties. The results will have timely societal implications: Contemporary EU youth suffer more ill-being and motivational problems than did previous generations. To help alleviate these problems, the applicant will develop and implement an unconditional-regard intervention in partnership with EU health-care professionals.", "To": ["2018-05-31, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["705217"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITY OF HULL", "UNIVERSIDAD DE GRANADA", "ASSOCIAZIONE ORLANDO", "UNIVERSITEIT UTRECHT", "UNIVERSIDAD DE OVIEDO", "UNIWERSYTET LODZKI", "ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA", "KOZEP-EUROPAI EGYETEM"], "EU_Contribution": ["EUR 3 719 102,04"], "Project_Title": ["GRACE: Gender and Cultures of Equality in Europe"], "Total_Cost": ["EUR 3 719 102,04"], "Country": ["United Kingdom", "Spain", "Italy", "Netherlands", "Spain", "Poland", "Italy", "Hungary"], "Project_ACR": ["GRACE"], "Technology_Description": "The aim of the GRACE (Gender and Cultures of Equality in Europe) project is to systematically investigate the cultural production of gender equalities within Europe. Extending the success of GEMMA, the Erasmus Mundus \u2018Masters of Excellence\u2019 in Women\u2019s and Gender Studies, the central objective of GRACE is to become the programme of reference for innovative interdisciplinary doctoral training for early career researchers. Previous scholarly work focuses on European gender equality policies. GRACE draws on innovative and interdisciplinary methodologies to investigate an under-examined aspect of those processes, namely the production of cultures of equality that underpin, enable and constrain those changing policy and legislative frameworks. Our methodological approach understands culture as neither normative frameworks nor ways of representing the world, but more fundamentally as the process through which people create the worlds they inhabit. The GRACE project will recruit, employ and provide advanced training for 15 ESRs who will research the production of cultures of gender equality across five specific sites where cultures of gender equalities are produced and contested by differently situated social agents. These five sites form the core of our research and training Work Packages, and are focused as follows: mediated cultures of gender equality (WP 1); urban cultures of gender equality (WP 2); intellectual and activist cultures of gender equality (WP 3); textual and artistic cultures of gender equality (WP 4); employing cultures of gender equality (WP 5). In sum, GRACE is designed to: equip the next generation of ESRs to play a leading role in developing advanced techniques for investigating the production of cultures of gender equality; translate creative and critical capacities into innovative cultural practices within and beyond academia; and enable them to take up positions as experts in producing new gender equalities cultures.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["675378"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["KARLSTADS UNIVERSITET", "WIRTSCHAFTSUNIVERSITAT WIEN", "USECON THE USABILITY CONSULTANTS GMBH", "JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN", "UNABHAENGIGES LANDESZENTRUM FUER DATENSCHUTZ", "UNISCON UNIVERSAL IDENTITY CONTROL GMBH", "TEL AVIV UNIVERSITY", "UNIVERSITY COLLEGE LONDON", "CRONTO LIMITED"], "EU_Contribution": ["EUR 3 376 517,40"], "Project_Title": ["Privacy and Usabiliy"], "Total_Cost": ["EUR 3 376 517,40"], "Country": ["Sweden", "Austria", "Austria", "Germany", "Germany", "Germany", "Israel", "United Kingdom", "United Kingdom"], "Project_ACR": ["Privacy.Us"], "Technology_Description": "With the rapid accumulation and processing of personal data by numerous organizations, it is of paramount importance to protect people from adverse uses of their data, while allowing them to enjoy the benefits the use of these data can possibly provide. This is the question of protecting citizens\u2019 privacy, while enabling them to make informed decisions regarding their actions with privacy implications.", "To": ["2019-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-12-01"], "Project_ID": ["675730"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM", "ACADEMISCH ZIEKENHUIS GRONINGEN", "UNIVERSITAT DE BARCELONA", "JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN"], "EU_Contribution": ["EUR 2 572 664,04"], "Project_Title": ["Deciphering the Metabolism of Haematological Cancers"], "Total_Cost": ["EUR 2 572 664,04"], "Country": ["United Kingdom", "Netherlands", "Spain", "Germany"], "Project_ACR": ["HaemMetabolome"], "Technology_Description": "It has long been realised that metabolism is central to cellular development, proliferation and homeostasis. Collectively, aberrations in metabolism are now recognised as a major hallmark of cancer, opening new avenues for personalised medicine. As haematological malignancies are multi-factorial diseases, our main emphasis will be on the integration of biomedical multi-omics data and computational systems modelling with the ultimate aim to understand metabolic regulation in haematological cancers. HaemMetabolism is design to unravel the regulatory mechanisms that link cell cycle control and metabolism. For this we will screen a panel of haematological cancer cell lines for the metabolic phenotypes and against a library of inhibitors. Gene-function analyses will be performed using shRNA libraries directed against key metabolome regulators. Validation will occur in primary patient samples in vitro and in vivo in preclinical humanized niche xenograft mouse models. A systems biomedicine approach will be integrated build genome-scale transcriptional models that explain deregulated metabolic pathways relevant for the development of haematological malignancies. This work will not only open new avenues for drug discovery but will also provide a multi-disciplinary framework for student training in biomedical technologies.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-EJD - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-EJD)"], "Funding_scheme": ["MSCA-ITN-EJD - European Joint Doctorates"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["675790"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM", "UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 1 499 875"], "Project_Title": ["Fickle Formulas. The Political Economy of Macroeconomic Measurement"], "Total_Cost": ["EUR 1 499 875"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["FICKLEFORMS"], "Technology_Description": "Macroeconomic indicators are integral to economic governance. Measurements of growth, unemployment, inflation and public deficits inform policy, for example through growth targets and the inflation-indexation of wages. These indicators tell us \u201chow economies are doing\u201d and citizens often punish politicians who fail to deliver on them.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["637683"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["SCIENCE AND TECHNOLOGY FACILITIES COUNCIL"], "EU_Contribution": ["EUR 2 548 800"], "Project_Title": ["Rutherford International Fellowship Programme"], "Total_Cost": ["EUR 5 097 600"], "Country": ["United Kingdom"], "Project_ACR": ["RIFP"], "Technology_Description": "The Rutherford International Fellowship Programme (RIFP) will be a new, high-quality Post-Doctoral scheme aimed at research excellence and promoting researcher mobility and training.", "To": ["2020-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2014-FP - Marie Sk\u0142odowska-Curie Co-funding of regional, national and international programmes (COFUND-FP)"], "Funding_scheme": ["MSCA-COFUND-FP - Fellowship programmes"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations"], "From": ["2015-07-01"], "Project_ID": ["665593"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2014"]}, -{"Partners": ["PERCUROS BV", "ACADEMISCH ZIEKENHUIS LEIDEN", "TECHNISCHE UNIVERSITEIT DELFT", "UNIVERSITA DEGLI STUDI DI CAMERINO", "TECOBIOSCIENCES GMBH", "UNIVERSITEIT VAN AMSTERDAM", "UNIVERSITETET I BERGEN", "HELSE BERGEN HF*HAUKELAND UNIVERSITY HOSPITAL", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "THE UNIVERSITY OF SHEFFIELD", "UNIVERSITEIT MAASTRICHT", "JENACELL GMBH", "MEDRES-MEDICAL RESEARCH GMBH", "ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM"], "EU_Contribution": ["EUR 3 922 309,44"], "Project_Title": ["Image-Guided Surgery (IGS) and Personalised Postoperative Immunotherapy To Improving Cancer Outcome"], "Total_Cost": ["EUR 3 922 309,44"], "Country": ["Netherlands", "Netherlands", "Netherlands", "Italy", "Germany", "Netherlands", "Norway", "Norway", "Switzerland", "United Kingdom", "Netherlands", "Germany", "Germany", "Netherlands"], "Project_ACR": ["ISPIC"], "Technology_Description": "The basic concept of our proposal is to develop nanoparticle-based encapsulated libraries of different immunotherapeutic biomolecules for treatment after surgery as part of a novel cancer management strategy. The current state-of-art for the management of cancer starts with surgery, after identification of an accessible tumour mass. Surgery remains an effective treatment option for many types of cancer today and it is considered curative treatment for most solid tumours. It forms part of a multidisciplinary approach used in conjunction with radiotherapy or chemotherapy. These approaches, however, have several limitations, including inability of surgical resection to affect distal metastatic disease, toxicity to healthy tissues with chemotherapy and lack of effectiveness of radiation therapy in more aggressive tumours. The observation that cancer can relapse months or years after initial surgery implies that micrometastases still resides within the body in a latent state. Our proposal is to take cancer therapy to beyond state-of-art by implementing techniques which will take us into new directions. This includes a) new methods to identify immune gene profiles and biomarkers b) transgenic mouse models where the complex interactions that underlie immune function can be visualised as multiplexed events in real time and c) the use of nanoparticle-based libraries of immune modulating reagent combinations. There are three key objectives within this project: i) to use immune gene signatures to monitor disease progression and therapeutic efficacy of immunotherapy combinations on nanoparticle-based platforms, ii) to optimise the platform to encapsulate libraries of immune components for more personalised, accurate and timely delivery of the payload to its intended target and iii) to optimise the overall cancer management process of image-guided surgery followed by postoperative immunotherapy so that we can ultimately provide a lifetime of protection against cancer.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Netherlands"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["675743"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK", "JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN", "ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON", "UNIVERSITY OF BATH", "FACHHOCHSCHULE NORDWESTSCHWEIZ", "H. Lundbeck A/S", "MERCK KOMMANDITGESELLSCHAFT AUF AKTIEN", "PHARMATEN ANONYMOS VIOMICHANIKI KAI EMPORIKI ETAIREIA PHARMAKEFTIKON KAI KALLYNTIKON PROIONTON", "SIRIUS ANALYTICAL INSTRUMENTS LTD", "Janssen Pharmaceutica NV"], "EU_Contribution": ["EUR 3 856 253,04"], "Project_Title": ["Pharmaceutical Education And Research with Regulatory Links: Innovative drug development strategies and regulatory tools tailored to facilitate earlier access to medicines"], "Total_Cost": ["EUR 3 856 253,04"], "Country": ["Ireland", "Germany", "Greece", "United Kingdom", "Switzerland", "Denmark", "Germany", "Greece", "United Kingdom", "Belgium"], "Project_ACR": ["PEARRL"], "Technology_Description": "The European Pharma industry is a major contributor to EU well-being, both in public health and economic (sales >200 billion \u20ac/year) terms. To maintain global leadership, it must respond to challenges from low-cost producers e.g. China by bringing new drug molecules to market in a streamlined, cost-effective manner. This strategy is underscored by recent initiatives of European regulators to expedite the approval of \u201cbreakthrough drugs\u201d so patients can gain earlier access to life-saving drugs. To realise these goals, scientists with an integral understanding of drug development and regulatory approval processes are urgently needed. ", "To": ["2020-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-05-01"], "Project_ID": ["674909"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["KING'S COLLEGE LONDON", "KING'S COLLEGE LONDON"], "EU_Contribution": ["EUR 1 947 665"], "Project_Title": ["Dark Matter and the Early Universe in the LHC Era"], "Total_Cost": ["EUR 1 947 665"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["DARKHORIZONS"], "Technology_Description": "The discovery of a Higgs like particle in its first science run shows that we are truly in the LHC era and when collisions resume we will learn more about the physics of the TeV scale. ", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["648680"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["UNIVERSITY OF BRISTOL", "UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 1 548 738"], "Project_Title": ["New Catalytic Asymmetric Strategies for N-Heterocycle Synthesis"], "Total_Cost": ["EUR 1 548 738"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["CatHet"], "Technology_Description": "Medicinal chemistry requires more efficient and diverse methods for the asymmetric synthesis of chiral scaffolds. Over 60% of the world\u2019s top selling small molecule drug compounds are chiral and, of these, approximately 80% are marketed as single enantiomers. There is a compelling correlation between drug candidate \u201cchiral complexity\u201d and the likelihood of progression to the marketplace. Surprisingly, and despite the tremendous advances made in catalysis over the past several decades, the \u201cchiral complexity\u201d of drug discovery libraries has actually decreased, while, at the same time, for the reasons mentioned above, the \u201cchiral complexity\u201d of marketed drugs has increased. Since the mid-1990s, there has been a notable acceleration of this \u201ccomplexity divergence\u201d. Consequently, there is now an urgent need to provide efficient processes that directly access privileged chiral scaffolds. It is our philosophy that catalysis holds the key here and new processes should be based upon platforms that can exert control over both absolute and relative stereochemistry. In this proposal we outline the development of a range of N-heteroannulation processes based upon the catalytic generation and trapping of unique or unusual classes of organometallic intermediate derived from transition metal insertion into C-C and C-N sigma-bonds. We will provide a variety of enabling methodologies and demonstrate applicability in flexible total syntheses of important natural product scaffolds. The processes proposed are synthetically flexible, operationally simple and amenable to asymmetric catalysis. Likely starting points, based upon preliminary results, will set the stage for the realisation of aspirational and transformative goals. Through the study of the organometallic intermediates involved here, there is potential to generalise these new catalytic manifolds, such that this research will transcend N heterocyclic chemistry to provide enabling methods for organic chemistry as a whole.", "To": ["2020-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-04-01"], "Project_ID": ["639594"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM", "UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 1 479 515"], "Project_Title": ["Profiling and targeting news readers \u2013 implications for the democratic role of the digital media, user rights and public information policy"], "Total_Cost": ["EUR 1 479 515"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["PersoNews"], "Technology_Description": "In the digital media environment, user attention is scarce and competition for \u2018eyeballs\u2019 is fierce. Profiling and targeting readers with customised news and advertisements that match their individual interests is widely seen as a solution. The personalization of news media content enables new financing strategies and means to capture the audience\u2019s attention. But personalisation is also part of a more fundamental paradigm shift in the media\u2019s role from public interest intermediary to personal information coach. This research will answer critical questions about the implications for individual users and contribute to a new normative theory of the role of personalised media in a democratic society.", "To": ["2020-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-08-01"], "Project_ID": ["638514"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["UNIVERSITY OF BRISTOL", "UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 1 233 672"], "Project_Title": ["Cultural Evolution of Kinship Diversity: Variation in Language, Cognition, and Social Norms Regarding Family"], "Total_Cost": ["EUR 1 233 672"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["VARIKIN"], "Technology_Description": "Why do human societies differ in whom they class as family? Why are cousins classed with siblings in some societies but not others? Accounting for the variable ways that cultures classify kin is an enduring puzzle. The VARIKIN project takes a cultural evolutionary approach to variety and unity and engages different fields\u2013cultural phylogenetics, corpus linguistics, and cross-cultural child development. VARIKIN-Evolution asks how and why does kinship diversity evolve across cultures and over time? Using comparative phylogenetic modeling of cultural evolution we investigate the dynamics of how kinship terminologies and family norms change in eight language families. Are there \u201cuniversal\u201d patterns of change, or does local cultural history and context determine changes in family organisation? How do social norms drive change in kinship terminology? VARIKIN-Usage investigates how people use kinship language by using corpus linguistics, surveys, and interviews to quantify patterns of usage in spoken and written language. How frequently are kinship terms used in different contexts and what meanings are more prevalent? Do patterns vary between languages, and can the patterns of usage at the individual level be linked to historical processes of change? VARIKIN-Development investigates how children acquire and understand kinship across cultures. Using participant observation and elicitation tasks, we characterise children\u2019s social learning of kinship in a small-scale, non-Western community. Are there cross-cultural patterns of acquisition? Can socialisation produce constraints on the kinds of kinship children can learn? These three research directions are united by a coherent framework for the integration of macro- and micro-evolutionary processes. With a highly multidisciplinary background, the Applicant is uniquely positioned to direct this vanguard project towards a comprehensive understanding of diversity in how we classify our social worlds.", "To": ["2020-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-07-01"], "Project_ID": ["639291"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["UNIVERSITY OF BRISTOL", "UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 2 499 938"], "Project_Title": ["Implementing Multi-Party Computation Technology"], "Total_Cost": ["EUR 2 499 938"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["IMPaCT"], "Technology_Description": "The goal of IMPaCT is to turn Multi-Party Computation (MPC) from a stage in which we are beginning to obtain practical feasibility results, to a stage in which we have fully practical systems. It has long been acknowledged that MPC has the potential to provide a transformative change in the way security solutions are enabled. As it presently stands this is currently only possible in limited applications; deployments in restricted scenarios are beginning to emerge. However, in turning MPC into a fully practical technology a number of key scientific challenges need to be solved; many of which have not yet even been considered in the theoretical literature. The IMPaCT project aims to address this scientific gap, bridge it, and so provide the tools for a future road-map in which MPC can be deployed as a widespread tool, as ubiquitous as encryption and digital signatures are today.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["690978"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM", "UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 1 498 352"], "Project_Title": ["Data activism: The politics of big data according to civil society"], "Total_Cost": ["EUR 1 498 352"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["DATACTIVE"], "Technology_Description": "With the diffusion of \u2018big data\u2019, citizens become increasingly aware of the critical role of information in modern societies. This awareness gives rise to new social practices rooted in technology and data, which I term \u2018data activism\u2019. While activists see massive data collection by governments and businesses as a challenge to civil rights, big data also offer new opportunities for collective action.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["639379"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["ASTON UNIVERSITY", "LZH LASER ZENTRUM HANNOVER E.V.", "FUNDACIO INSTITUT DE CIENCIES FOTONIQUES", "UNIVERSITAT DE BARCELONA", "AXOL BIOSCIENCE LTD", "Kite Innovation (Europe) Limited"], "EU_Contribution": ["EUR 3 225 890,50"], "Project_Title": ["Custom architecturally defined 3D stem cell derived functional human neural networks fortransformative progress in neuroscience and medicine"], "Total_Cost": ["EUR 3 225 891,25"], "Country": ["United Kingdom", "Germany", "Spain", "Spain", "United Kingdom", "United Kingdom"], "Project_ACR": ["MESO_BRAIN"], "Technology_Description": "The development of methods to isolate and generate human stem cells along with technology to selectively differentiate them into specific cell and tissue types has excited many with the promise of the ability to study human cell function and utilise them for regeneration in disease and trauma. However, to date, attempts to develop regenerative brain and central nervous system therapies have been disappointing, with the introduced stem cell derived neurons not integrating nor signalling physiologically with endogenous cells. A major confounding issue has been that derived neurons are grown in two dimensions, which does not mimic the in vivo three dimensional interactions nor the myriad developmental cues they would receive in vivo. ", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-1-2014 - FET-Open research projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-09-01"], "Project_ID": ["713140"], "Call_for_Proposal": ["H2020-FETOPEN-2014-2015-RIA"]}, -{"Partners": ["UNIVERSITAET BERN", "JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN", "IFOM FONDAZIONE ISTITUTO FIRC DI ONCOLOGIA MOLECOLARE", "UNIVERSITE LIBRE DE BRUXELLES", "MAGYAR TUDOMANYOS AKADEMIA SZEGEDIBIOLOGIAI KUTATOKOZPONT", "UNIVERSITE D'ARTOIS", "RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "STICHTING VU", "THE OPEN UNIVERSITY", "GENXPRO GMBH"], "EU_Contribution": ["EUR 3 067 402,32"], "Project_Title": ["Brain barriers training"], "Total_Cost": ["EUR 3 067 402,32"], "Country": ["Switzerland", "Germany", "Italy", "Belgium", "Hungary", "France", "Germany", "Switzerland", "Netherlands", "United Kingdom", "Germany"], "Project_ACR": ["BtRAIN"], "Technology_Description": "The brain barriers function to protect the central nervous system (CNS) from neurotoxic compounds. By the same traits they unfortunately block delivery of drugs to the CNS thus hindering proper diagnosis and effective treatment of neurological disorders including Alzheimer\u2019s disease and multiple sclerosis. The unusual complexity of the brain barriers has severely hampered progress in the market of CNS targeting therapeutics. BtRAIN bridges this gap by creating particular knowledge on vertebrate brain barrier signature genes and their specific roles in regulating brain barrier function in development, health, ageing and disease. Brain barrier signature genes will be identified by combining cross-species and cross-system brain barrier transcriptome analysis with dedicated bioinformatics. These data will be made available for brain barrier datamining in the userfriendly online platform BBBHub. Within BtRAIN, the side-by-side comparison of a unique and broad armamentarium of different vertebrate in vitro and in vivo brain barrier models will allow to develop and validate particular in vitro brain barrier models that are suited to reliably predict brain barrier function in vivo. Combined with an accompanying in depth analysis of the pathological alterations of the brain barriers during neurological disorders BtRAIN will create unique knowledge to overcome the unmet need for the development of diagnostic and therapeutic tools able to breach the brain barriers. In BtRAIN 12 academic, 6 non-academic partners and 1 European network will jointly train young researchers at unique interfaces of brain barrier research, bioinformatics, business development and science communication for an international research or entrepreneur career. To create this expert pool is the motivation for the involved partners as it will advance the Euopean capacity to bring innovative approaches to the untapped potential of the CNS therapeutic market.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-09-01"], "Project_ID": ["675619"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "IN Srl", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "WEIZMANN INSTITUTE OF SCIENCE", "EVOGENE LTD"], "EU_Contribution": ["EUR 4 871 410"], "Project_Title": ["Transforming the future of agriculture through synthetic photorespiration"], "Total_Cost": ["EUR 4 871 410"], "Country": ["Germany", "Italy", "United Kingdom", "Israel", "Israel"], "Project_ACR": ["FutureAgriculture"], "Technology_Description": "For a new green revolution to feed the continually increasing population, agriculture productivity will have to be significantly improved. Photorespiration represents a big challenge in this respect, because it dissipates energy and leads to the futile loss of CO2, thereby limiting plant growth yield. Implementing an efficient metabolic bypass for photorespiration can therefore increase the photosynthetic efficiency of many cultivated crops. Several such routes were previously proposed. However, these routes were limited to existing enzymes and pathways and provided only partial improvement. Here, we propose a radically different approach: to engineer entirely novel CO2-neutral or CO2-positive photorespiration bypasses based on novel enzyme chemistry that support significantly higher agricultural yields. These bypass routes could support 60% higher biomass yield per turn of the Calvin Cycle and >30% higher yield per ATP. Our project innovatively integrates different research disciplines and combines academic research with industrial implementation. In silico studies will integrate biochemical logic and pathway modelling to explore all possible photorespiration pathways and identify the most efficient routes. In vitro research will establish novel enzyme functions via enzyme engineering and directed evolution. Full pathways will be reconstituted and optimized in vitro using a novel mass spectrometry based platform. High in vivo activity will be selected by implementing the pathways in engineered E. coli strains. Enhanced photosynthetic efficiency will be demonstrated in cyanobacteria expressing the synthetic pathways. Finally, the most promising synthetic pathways will be implemented in higher plants and growth phenotypes will be monitored. The proposed project comprises a significant advance in synthetic biology \u2013 applying biochemical principles to modify the very core of carbon metabolism with synthetic pathways that carry multiple novel enzymatic functions.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-1-2014 - FET-Open research projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-01-01"], "Project_ID": ["686330"], "Call_for_Proposal": ["H2020-FETOPEN-2014-2015-RIA"]}, -{"Partners": ["UMEA UNIVERSITET", "THE UNIVERSITY OF MANCHESTER", "INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE", "SCIENCE AND TECHNOLOGY FACILITIES COUNCIL"], "EU_Contribution": ["EUR 3 907 375"], "Project_Title": ["Parallel Numerical Linear Algebra for Future Extreme-Scale Systems"], "Total_Cost": ["EUR 3 907 375"], "Country": ["Sweden", "United Kingdom", "France", "United Kingdom"], "Project_ACR": ["NLAFET"], "Technology_Description": "The NLAFET proposal is a direct response to the demands for new mathematical and algorithmic approaches for applications on extreme scale systems, as identified in the FETHPC work programme and call. This project will enable a radical improvement in the performance and scalability of a wide range of real-world applications relying on linear algebra software, by developing novel architecture-aware algorithms and software libraries, and the supporting runtime capabilities to achieve scalable performance and resilience on heterogeneous architectures. The focus is on a critical set of fundamental linear algebra operations including direct and iterative solvers for dense and sparse linear systems of equations and eigenvalue problems. Achieving this requires a co-design effort due to the characteristics and overwhelming complexity and immense scale of such systems. Recognized experts in algorithm design and theory, parallelism, and auto-tuning will work together to explore and negotiate the necessary tradeoffs. ", "To": ["2018-10-31, ongoing project |"], "Meta": [""], "Topic_s": ["FETHPC-1-2014 - HPC Core Technologies, Programming Environments and Algorithms for Extreme Parallelism and Extreme Data Applications"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations"], "From": ["2015-11-01"], "Project_ID": ["671633"], "Call_for_Proposal": ["H2020-FETHPC-2014"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA", "UNIVERSITY OF BRISTOL", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "CONSIGLIO NAZIONALE DELLE RICERCHE", "UNIVERSITAT WIEN", "UNIVERSITAET PADERBORN", "UNIVERSITAET ULM", "UNIVERSITE LIBRE DE BRUXELLES", "UNIVERSITY OF SOUTHAMPTON"], "EU_Contribution": ["EUR 2 681 713,75"], "Project_Title": ["Quantum Simulation on a Photonic Chip"], "Total_Cost": ["EUR 2 681 713,75"], "Country": ["Italy", "United Kingdom", "United Kingdom", "Italy", "Austria", "Germany", "Germany", "Belgium", "United Kingdom"], "Project_ACR": ["QUCHIP"], "Technology_Description": "Simulation is a fundamental computational tool for modern science with applications ranging from drug design to materials science. Quantum simulators have the potential to revolutionize the way simulations are performed by accessing system sizes that are untractable in classical machines. As a result, they will become a suite of powerful and precise instruments enabling the investigation of relevant phenomena in the dynamics of complex quantum systems, such as quantum transport and energy transfer, as well as implementing quantum improved computation - tasks hard to simulate classically. QUCHIP aims at implementing quantum simulation on integrated photonic processors. Photons present unique advantages deriving from their mobility and the immunity to decoherence: these two features make them substantially different from any other quantum system. Moreover integrated quantum photonics capitalizes on the multi-billion dollar investment already placed into photonics development and commercialization. QUCHIP will exploit these advantages to implement quantum walk experiments in which several photons propagate over complex circuit architectures \u201cjumping\u201d between different waveguides. This platform represents the most resource-efficient quantum computation scheme to date: Boson Sampling. Recent computational theory findings have shown exceptional potential for this scheme to achieve the quantum supremacy regime in which quantum systems surpass classical ones. QUCHIP will develop new photonic technologies, ranging from on-chip sources of single photons to complex waveguide architectures and on-chip detectors. We will explore the dynamics of noisy quantum networks and develop practical schemes to demonstrate key structural and functional elements of the network dynamics. The benefits range from insights into the dynamics of complex systems to a dramatic push forward for the realization of an experimental device whose output cannot be formally calculated by classical means.", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["FETPROACT-3-2014 - Quantum simulation"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-03-01"], "Project_ID": ["641039"], "Call_for_Proposal": ["H2020-FETPROACT-2014"]}, -{"Partners": ["CHALMERS TEKNISKA HOEGSKOLA AB", "UNIVERSITAET STUTTGART", "TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY", "INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE", "UNIVERSITAET AUGSBURG", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "UNIVERSITEIT GENT", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION", "FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS", "THE UNIVERSITY OF EDINBURGH", "RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN", "THE UNIVERSITY OF MANCHESTER", "ETA SCALE AB", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.", "FUNDACION UNIVERSITARIA SAN ANTONIO DE CARTAGENA", "NANE RAZVAN"], "EU_Contribution": ["EUR 1 489 980,75"], "Project_Title": ["EuroLab-4-HPC: Foundations of a European Research Center of Excellence in High Performance Computing Systems"], "Total_Cost": ["EUR 1 489 981,25"], "Country": ["Sweden", "Germany", "Israel", "France", "Germany", "Switzerland", "Belgium", "Switzerland", "Spain", "Greece", "United Kingdom", "Germany", "United Kingdom", "Sweden", "Germany", "Spain", "Netherlands"], "Project_ACR": ["EuroLab-4-HPC"], "Technology_Description": "Europe has built momentum in becoming a leader in large parts of the HPC ecosystem. It has brought together technical and business stakeholders from application developers via system software to exascale systems. Despite such gains, excellence in high performance computing systems is often fragmented and opportunities for synergy missed. To compete internationally, Europe must bring together the best research groups to tackle the longterm challenges for HPC. These typically cut across layers, e.g., performance, energy efficiency and dependability, so excellence in research must target all the layers in the system stack. ", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["FETHPC-2-2014 - HPC Ecosystem Development"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-09-01"], "Project_ID": ["671610"], "Call_for_Proposal": ["H2020-FETHPC-2014"]}, -{"Partners": ["UNIVERSITEIT GENT", "TELECOMMUNICATION SYSTEMS INSTITUTE", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "POLITECNICO DI MILANO", "UNIVERSITEIT VAN AMSTERDAM", "RUHR-UNIVERSITAET BOCHUM", "MAXELER TECHNOLOGIES LIMITED", "SYNELIXIS LYSEIS PLIROFORIKIS AUTOMATISMOU & TILEPIKOINONION MONOPROSOPI EPE", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 3 989 930,50"], "Project_Title": ["Exploiting eXascale Technology with Reconfigurable Architectures"], "Total_Cost": ["EUR 3 989 931,25"], "Country": ["Belgium", "Greece", "United Kingdom", "Italy", "Netherlands", "Germany", "United Kingdom", "Greece", "United Kingdom"], "Project_ACR": ["EXTRA"], "Technology_Description": "To handle the stringent performance requirements of future exascale High Performance Computing (HPC) applications, HPC systems need ultra-efficient heterogeneous compute nodes. To reduce power and increase performance, such compute nodes will require reconfiguration as an intrinsic feature, so that specific HPC application features can be optimally accelerated at all times, even if they regularly change over time. ", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["FETHPC-1-2014 - HPC Core Technologies, Programming Environments and Algorithms for Extreme Parallelism and Extreme Data Applications"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["671653"], "Call_for_Proposal": ["H2020-FETHPC-2014"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM", "UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 1 999 830"], "Project_Title": ["Becoming Men: Performing responsible masculinities in contemporary urban Africa"], "Total_Cost": ["EUR 1 999 830"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["Becoming Men"], "Technology_Description": "This anthropological study examines the reconfiguration of masculinities in urban Africa over the last 30 years. Focusing on how practices and discourses of empowerment and equality shape male subjectivities, this study builds upon a significant body of nuanced research on masculinities in Africa. Since the mid-1980s academic and public discourses have depicted African masculinity as both precarious and predatory. Economic insecurity, urbanization, shifting gender norms, and growing gender parity have accompanied claims that African masculinity is \u2018in crisis\u2019. More recently, new stories of urban men embracing responsible fatherhood, condemning intimate partner violence, and demanding homosexual rights have emerged as exemplars of progressive possibility. To disentangle these seemingly competing claims about African masculinities and shed light on the scientific, political, and economic projects that shape them, this research theorises that the discourses and practices that pathologise and politicise masculinity are simultaneously performing and producing gendered selves on multiple scales in the name of gender equality. Recently, \u2018male involvement\u2019 has become a rallying cry throughout the vast global development assemblage, around which governments, NGOs, research networks, activists, and local communities fight gender inequality to promote health, economic development, and human rights. In this research, a range of male-involvement initiatives provides a lens through which to study how masculinities are diversely imagined, (re)configured, and performed through men\u2019s engagements with this assemblage, in both its local and global manifestations. Multi-sited ethnographic research will focus on six cities where the PI has active research ties: Nairobi and Kisumu, Kenya; Johannesburg and Durban, South Africa; and Dar es Salaam and Mwanza, Tanzania.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["647314"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["UNIVERSIDAD DE BURGOS", "AGENZIA NAZIONALE PER LE NUOVE TECNOLOGIE, L'ENERGIA E LO SVILUPPO ECONOMICO SOSTENIBILE", "CONSORZIO INTERUNIVERSITARIO PER LO SVILUPPO DEI SISTEMI A GRANDE INTERFASE", "MISKOLCI EGYETEM", "PANEPISTIMIO PATRON", "MBN NANOMATERIALIA SPA", "ADVAMAT SRO", "ADMATIS KUTATO, GYARTO ES KERESKEDELMI KORLATOLT FELELOSSEGU TARSASAG", "BRIMATECH SERVICES GMBH", "AEROSPACE & ADVANCED COMPOSITES GMBH", "EASN Technology Innovation Services BVBA"], "EU_Contribution": ["EUR 2 698 062,50"], "Project_Title": ["Innovative Coarsening-resistant Alloys with enhanced Radiation tolerance and Ultra-fine -grainedStructure for aerospace application"], "Total_Cost": ["EUR 2 698 062,50"], "Country": ["Spain", "Italy", "Italy", "Hungary", "Greece", "Italy", "Czech Republic", "Hungary", "Austria", "Austria", "Belgium"], "Project_ACR": ["ICARUS"], "Technology_Description": "ICARUS proposes a new thermodynamic methodology able to identify the elements and the relative chemical composition allowing a nanocrystalline state to occupy a relative minimum of the Gibbs free energy, which makes the nanostructure reasonably stable against coarsening. This approach will be integrated, in synergy with multiscale and thermodynamic (Nano-Calphad) modeling, in order to implement a High-Throughput Screening (HTS) tool that will open a new horizon of discovery and exploration of multinary thermal stable nanocrystalline alloys, exhibiting superb tailored properties. ICARUS brings a radically new concept by addressing a still unsolved problem in the stabilization of nanocrystalline alloys. The materials discovery approach of ICARUS will be synergistic with the forefront industrial production technologies of nanomaterials and alloys. ", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-1-2014 - FET-Open research projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-09-01"], "Project_ID": ["713514"], "Call_for_Proposal": ["H2020-FETOPEN-2014-2015-RIA"]}, -{"Partners": ["UNIVERSITY OF PORTSMOUTH HIGHER EDUCATION CORPORATION", "UNIVERSITY OF PORTSMOUTH HIGHER EDUCATION CORPORATION"], "EU_Contribution": ["EUR 1 701 132,50"], "Project_Title": ["Cosmological Tests of Gravity"], "Total_Cost": ["EUR 1 701 132,50"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["CosTesGrav"], "Technology_Description": "Einstein\u2019s theory of General Relativity (GR) is tested accurately within the local universe i.e., the solar system, but this leaves open the possibility that it is not a good description at the largest scales in the Universe. The standard model of cosmology assumes GR as a theory to describe gravity on all scales. In 1998, astronomers made a surprising discovery that the expansion of the Universe is accelerating, not slowing down. This late-time acceleration of the Universe has become the most challenging problem in theoretical physics. Within the framework of GR, the acceleration would originate from an unknown \u201cdark energy.\u201d Alternatively, it could be that there is no dark energy and GR itself is in error on cosmological scales. The standard model of cosmology is based on a huge extrapolation of our limited knowledge of gravity. This discovery of the late time acceleration of the Universe may require us to revise the theory of gravity and the standard model of cosmology based on GR. ", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["646702"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["Oscillatory long-Range Coherence in Attention"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["ORCA"], "Technology_Description": "Attention -the ability to focus selectively on task relevant information and resist distraction- plays a critical role in many everyday life situations, such as in school or while driving. With an almost constant stream of information reaching us through smart phones and computers, our world becomes increasingly distracting, requiring enhanced attentional capabilities. This calls for new approaches to improve attention, also benefiting patients populations suffering from attention deficits. Is it possible to safely improve attention without medication? And how does the brain actually guides attention and resist distractions? The proposed research aims to answer these questions by combining a novel brain stimulation technique, transcranial alternating current stimulation (tACS) with state of the art neuroimaging methods. It will specifically test the intriguing hypothesis that attention can be enhanced by synchronizing rhythmic activity between two brain regions previously shown to be involved in attention. In the first study I will assess the effects of stimulation on attention performance, while simultaneously measuring neural activity using electroencephalogram (EEG). This will allow me to determine to what extent tACS can improve attention and investigate the causal role of neural oscillations in attention. In the second study, tACS will be combined with functional magnetic resonance imaging (fMRI) allowing to bridge the literature on neural oscillations (derived from EEG research) and attention networks (derived from fMRI research). Specifically, it will provide novel insights into the exact neural network subserving oscillatory activity associated with attention. Taken together, this project will not only investigate an innovative way to improve attention, with important implication for future clinical studies, but will also have a major contribution to cognitive neuroscience theories of attention.", "To": ["2018-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-08-01"], "Project_ID": ["702402"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITAET ULM", "UNIVERSITAET STUTTGART", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "JOHANNES GUTENBERG-UNIVERSITAT MAINZ", "AARHUS UNIVERSITET", "THE UNIVERSITY OF NOTTINGHAM", "UNIVERSITY OF DURHAM", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG", "CENTRE INTERNATIONAL DE RECHERCHE AUX FRONTIERES DE LA CHIMIE", "CONSIGLIO NAZIONALE DELLE RICERCHE", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "UNIVERSITEIT VAN AMSTERDAM", "UNIVERSITAET INNSBRUCK", "TECHNISCHE UNIVERSITEIT EINDHOVEN", "UNIVERSITAET KASSEL"], "EU_Contribution": ["EUR 4 383 000"], "Project_Title": ["Rydberg Quantum Simulators"], "Total_Cost": ["EUR 4 695 000"], "Country": ["Germany", "Germany", "France", "Germany", "Denmark", "United Kingdom", "United Kingdom", "Switzerland", "Germany", "France", "Italy", "Germany", "Netherlands", "Austria", "Netherlands", "Germany"], "Project_ACR": ["RYSQ"], "Technology_Description": "Quantum Simulators provide new levels of understanding of equilibrium and out-of-equilibrium properties of many-body quantum systems, one of the most challenging problems in physics. The main objective of the RYSQ project is to use Rydberg atoms for quantum simulations, because their outstanding versatility will allow us to perform a great variety of useful quantum simulations, by exploiting different aspects of the same experimental and theoretical tools. By implementing not only one but a whole family of Rydberg Quantum Simulators, the project will address both the coherent and incoherent dissipative dynamics of many-body quantum systems, with potential applications in the understanding and design of artificial light harvesting systems, large quantum systems with controlled decoherence, and novel materials. This will be achieved by building upon a novel generic approach to quantum simulation, where Rydberg atoms allow both digital (gate) and analog (interaction) simulations. ", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["FETPROACT-3-2014 - Quantum simulation"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-03-01"], "Project_ID": ["640378"], "Call_for_Proposal": ["H2020-FETPROACT-2014"]}, -{"Partners": ["JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN", "JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN"], "EU_Contribution": ["EUR 1 499 693,71"], "Project_Title": ["Non-coding RNA in Vascular Ageing"], "Total_Cost": ["EUR 1 499 693,71"], "Country": ["Germany", "Germany"], "Project_ACR": ["NOVA"], "Technology_Description": "Life expectancy in the European Union is rising and the prevalence of age-induced cardiovascular disease increases concomitantly. Endothelial dysfunction is a hallmark of aging in the vasculature and is the underlying cause of many cardiovascular disorders, like hypertension, acute myocardial infarction and stroke. This proposal aims to better understand the molecular mechanisms behind aging that lead to endothelial dysfunction.", "To": ["2020-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-04-01"], "Project_ID": ["638178"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Formal Truth in Epistemology"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["TREPISTEME"], "Technology_Description": "Understanding the notions of truth and knowledge has been at the root of the philosophical enterprise since the very beginning. It turns out that these notions are intimately related and that understanding truth requires understanding knowledge and vice versa. Constitutive questions concerning these notions, such as \u201cAre there truths that cannot be known?\u201d can only be understood, let alone answered, if we have a grasp of both notions. Epistemology, conceived as the study of human knowledge, should therefore simultaneously investigate the notion of truth. Surprisingly, very little research has been conducted from this perspective. Rather research on truth and research on knowledge has been mostly conducted independently. This project will approach the traditional epistemological question of the definition of knowledge from this integrated perspective, and attempt to bridge a gap between current research in epistemology and research on theories of truth. ", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["703539"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM", "UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Causes and consequences of change in public opinion about Europe"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["EUROPINIONS"], "Technology_Description": "Causes and consequences of change in public opinion about Europe", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["647316"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM", "UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 1 497 764"], "Project_Title": ["Corporate Network Governance: Power, Ownership and Control in Contemporary Global Capitalism"], "Total_Cost": ["EUR 1 497 764"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["CORPNET"], "Technology_Description": "The character of global business networks has long fascinated but continues to divide scholars of global markets and governance. A well-established perspective looks at the changes in global networks and sees an emerging cohesive transnational capitalist class. However, a rival line of inquiry sees the rise of competing corporate elites. Scholars also disagree on the origins of emergent patterns of corporate networks. Do they reflect institutional preferences of corporate and political elites? Or are they unintended by-products of corporate conduct? Third, there are fundamental differences of opinion on how patterns of global corporate ownership relate to actual power in the governance of such networks.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["638946"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["The unique dioxygenases of phytophagous spider mites: new enzyme players in plant-herbivore interactions?"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["DOGMITE"], "Technology_Description": "Detoxification of poisonous xenobiotics in animals is typically performed by multi-gene enzyme families. Within arthropods, only insect genomes have been studied in detail where these families are well characterized. I recently uncovered a new enzyme family in the genome of a non-insect arthropod, the extremely polyphagous plant-feeding mite Tetranychus urticae and showed that this proliferated family was acquired via horizontal gene transfer from a fungal donor. The family codes for intradiol ring cleaving dioxygenases which cleave a particular set of aromatic structures, commonly found in pesticides and plant metabolites. Here, I propose to functionally characterize this exciting new gene family and to elucidate its role in xenobiotic detoxification, with a focus on plant secondary metabolites. First, to create a general picture, I will map the in situ expression of dioxygenases and time their responses to plant-derived secondary defense metabolites. Second, guided by preliminary results, I plan to study how these new herbivore enzymes counteract polyphenol oxidases, well-known plant defense enzymes that act against herbivores and target the same class of substrates. State-of-the-art plant transformation experiments will be performed in order to meticulously dissect their counterplay. Finally, by means of an unbiased multi-layered strategy, I will functionally characterize these new dioxygenases. Dioxygenases will be introduced into biological systems by functional expression in E. coli or insect cells, and by genetically transforming Drosophila. Cutting-edge differential metabolomics will identify the substrates and reaction products. By means of this project, I expect to unravel the selective advantage of this new family for phytophagous mites and open up avenues to exciting biotechnological applications which I expect to extend well beyond agriculture.", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["658795"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITAET KASSEL", "UNIVERSITAET KASSEL"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Human Cooperation to Protect the Global Commons"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["HUCO"], "Technology_Description": "The objectives of this research are to reveal the nature of large-scale human cooperation and to develop strategies for the protection of our global environment. Human activities are now the major driver of change in the biosphere, including the climate, the water cycle, and the distribution of species and biodiversity \u2013 with adverse effects that range from the local to the global scale. Since there is no world government that can enforce the protection of the global commons we have to rely on voluntary cooperation by sovereign actors. Previous findings from various disciplines have taught us important lessons about the nature of human cooperation. However, these literatures have almost exclusively focused on local or regional cooperation problems and their findings cannot be readily transferred to the international level. The research proposed here will fill this crucial gap. The methodological approach is genuinely interdisciplinary. In particular, the project will use and combine theoretical, experimental, evolutionary, and empirical methods. The interdisciplinary research team will start by analyzing case studies of international cooperation (or lack thereof). In an iterative process, the case-specific results will be explored in a rigorous context-free analysis using theoretical modeling, experiments, and simulations. With this, the project will: systematically analyze human cooperation from the local to the global scale and the differences between those scales; investigate which institutional arrangements enhance or prevent cooperative behavior at the global level; investigate whether individuals and groups are able to choose the right institutions and which factors determine their choice; synthesize the results to derive theoretical and practical insights about human cooperation and develop effective strategies for the management of the global commons; bring forward the integration of concepts and methods across disciplines for the study of human cooperation.", "To": ["2020-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-08-01"], "Project_ID": ["636746"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Probabilistic Assessment of Reduction and Transfer of Natural Earthquake Risk"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["PARTNER"], "Technology_Description": "Seismic risk management in fast-growing populated seismic areas is a challenge for governments and communities in case of catastrophic events. Seismic resilience options are considered to mitigate risk, by either reducing the risk through vibration-control designs of risky assets, or by transferring the risk into the capital markets, through disaster financing options or (re)insurers. Both strategies require a good understanding of the seismic risk, which can be achieved only through thorough ground-motion uncertainty quantification and propagation to structural response, and accurate estimates of damage, cost and downtime estimates of the affected assets.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["704679"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["KING'S COLLEGE LONDON"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["GENOMIC AND METABOLIC REGULATION OF METASTATIC CANCER STEM CELLS"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["GENMETASTEM"], "Technology_Description": "The major causes of cancer deaths are relapse and resistance to current therapies associated with the presence of cancer stem cells (CSCs) and metastatic growth in distant organs. CSCs have the ability to self-renew and differentiate in non-CSCs. In breast cancer, acquisition of stemness properties has been closely related to epithelial-mesenchymal transition (EMT), a key process in cancer invasion and metastasis triggered via Rho-ROCK mediated actomyosin contractility. Interestingly, in melanoma, transition from elongated-mesenchymal to amoeboid mode of movement (MAT) driven by Rho-ROCK signalling has been associated with increased stemness. Furthermore, preliminary data from host lab shows that actomyosin cytoskeletal regulates glutamine metabolism in both melanoma and breast cancer cells. Metabolic cues participate in stem cell self-renewal regulation, suggesting that, in very contractile cells, the regulation of EMT, metastatic spread and tumour initiation might be functionally linked to stemness via metabolic clues. Nevertheless, how very contractile cells regulate genes involved in all these processes remains unexplored. As increasing contractility via EMT in carcinoma cells or via MAT in melanoma cells correlates with increasing stemness, we hypothesize a molecular link between the pathways regulating both migration and stemness abilities, which will be maintained across tumour types (from carcinoma to melanoma). The main goal of this proposal is to understand how tumour cells can acquire stem cell traits to successfully metastasize and how this can be regulated by the actomyosin cytoskeletal by using an interdisciplinary approach that combines state-of-the-art techniques in molecular and cellular biology, biochemistry, in vivo imaging and animal models. This will allow to identify key important genes regulating both stemness traits and metastatic spread with the ultimate goal of unravelling novel drug targets and prognostic markers of distant relapse.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["659022"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["KING'S COLLEGE LONDON"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Engineering the 3D Niche to enHANCE functionality of hepatocytes derived from human iPSCs"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ENHANCE"], "Technology_Description": "Induced pluripotent stem cell derived hepatocytes (i-Heps) afford us the exciting possibility of redressing the growing shortage in liver transplantation tissue and heralding in a new era of patient specific drug and disease modelling. Clinical applications are restricted by their poor functionality in comparison to the gold standard \u2013 freshly isolated primary hepatocytes. Emerging evidence suggests the three dimensional environment surrounding a cell (the niche) critically influences cellular function. The objective of ENHANCE is to identify relevant factors from the extracellular niche which promote i-Hep function in 3D and the mechanisms by which they achieve this. This new knowledge will be used to generate functionally optimized i-Hep constructs suitable for clinical transplantation, with proof of concept studies being performed in rodent models of liver failure. This European Fellowship at Kings College London will provide the researcher with advanced training in iPSC technology, i-Hep generation, 2D niche component screening, 3D cell engineering and animal transplantation. A secondment to SME DefiniGEN Ltd will evaluate the feasibility of transfer to a commercial i-Hep production platform as a critical step towards clinical trials.", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["705607"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["Trauma Studies in the Digital Age: The Impact of Social Media on Trauma Processing in Life Narratives and in Trauma Literature: the Case of Hungary"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["TRAPRODIG"], "Technology_Description": "The aim of the TRAPRODIG project is to analyse cultural and literary trauma processing in the framework of digital memory studies, particularly in relation to the similarities and differences of collective trauma processing and trauma literature in modern democracies and dictatorships; with a special trans-cultural focus on the case of Hungary as a post-socialist country with unresolved twentieth century collective traumas and on life narratives of Hungarian migrants in Europe, especially in the United Kingdom.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["701883"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["KING'S COLLEGE LONDON"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Re-Exploring the Logic of Gandhian Violence: Gandhi and his Followers in the Quit India Movement, Bengal 1942-45"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["Gandhian Politics"], "Technology_Description": "'Re-Exploring the Logic of Gandhian Violence: Gandhi and his Followers in the Quit India Movement, Bengal 1942-45", "To": ["2018-09-12, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-13"], "Project_ID": ["702950"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["KING'S COLLEGE LONDON"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Tracing the global fertility chain- A new political economy of outsourced reproduction"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["globalfertilitychain"], "Technology_Description": "In a new kind of post-Fordist niche, called the reproductive bio-economy, organised around the \u201cflow\u201d of reproductive substances and organs, such as egg cells, embryos and wombs, women are increasingly commercialising their bodies by working as oocyte vendors, surrogate mothers or tissue providers. There is fundamental disagreement among scholars and policy makers on how the reproductive bio-economy should be organised. Market critics propose a gift economy based on altruistic donations and informed consent, while market proponents encourage the commercialisation of reproductive tissues and the remuneration of tissue providers. This research addresses and moves beyond the conflicting terms (gift v. commodity, reproduction v. production, labour v. donation) in which the debate has been framed. It empirically investigates how (bio-)value is created and governed in one particular strand of the \u201cactually existing\u201d reproductive bio-economy, i.e. the global fertility industry, by exploring the intricate ways in which reproductive tissues and labour move in and out of a commodity state as they move through different regimes of governance. By ethnographically mapping the shifting regimes of labour and property in one specific fertility chain that is becoming increasingly popular, i.e. between Israel/Palestine, South Africa (oocyte vending) and Nepal (surrogacy), the volatile boundaries between gift and commodity, value and waste, labour and donation, property and entitlement will be unpacked. This will be done in an attempt to discern \u201chidden strategies of resistance\u201d of female reproductive workers in the Global South, and propose alternative and more emancipatory ways of configuring the governance of the reproductive bio-economy.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["704261"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Communication through Polarity-Switchable Foldamers"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["REFOLDAMER"], "Technology_Description": "We propose to develop a new, artificial but bio-inspired mechanism for communicating information in chemical systems, by using the potential for hydrogen-bond reorganisation of novel dynamic 'refoldable foldamers', combined with biology's information storage mechanisms. Biological information is encoded in DNA or RNA by two dimensional arrangements of hydrogen bond donors and acceptors in nucleotide sequences: we will innovate nanoscale communication devices that read information encoded in this way, and translate it directly into a chemical feature (catalytic activity, ligand-binding ability) at a site remote from the source of information. Conceptually we shall telescope the biological processes of transcription and translation into a single conformational event in a single molecule.", "To": ["2018-04-03, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-04-04"], "Project_ID": ["701318"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["KING'S COLLEGE LONDON"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["The War on Music. Heritage, Islam and Peacekeeping in relation to the Islamist attacks in Mali"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["WARMUSIC"], "Technology_Description": "This project offers a critical approach to the recent phenomenon of the Islamist attacks on cultural heritage. Its objectives are to analyze 1) the performative and musical dimensions of Islamic identity during conflicts and 2) the global protection policies of the so-called \u201cintangible heritage\u201d. In addition, it aims at 3) building a new paradigm for post-conflict reconstruction and peacekeeping in collaboration with King\u2019s College London experts and with international organizations (Secondment). The research develops around a central case-study: the attacks on music (formal interdictions, threats to musicians, destruction of musical instruments) that occurred during the Northern Mali occupation by armed groups claiming to be Islamists in 2012, and the intangible heritage protection and reconstruction programs implemented by the Malian Government, UNESCO, UN peace force and the European Union. ", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["702725"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["Radical Contextualism and the Science of Meaning"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["RContext"], "Technology_Description": "The project investigates the impact that \u2018radical contextualism\u2019 (RC) has upon certain foundational issues in the philosophy of language, formal semantics, and philosophy of science. What motivates RC is the idea that our interpretation of a word, and what we refer to by using it, might be very different on different occasions of use. This suggests that our ability to interpret words, or to understand what they mean, depends in part on our being familiar with certain features of the occasions on which words are actually put to use. However, since communicative occasions are not systematically tractable, this seems to render systematic theories of meaning impossible. My chief objective is to think of a way out of this difficulty whilst taking the intuition behind RC seriously. ", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["656273"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITEIT UTRECHT", "UNIVERSITEIT UTRECHT", "UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 1 907 944"], "Project_Title": ["Technique in the Arts. Concepts, Practices, Expertise (1500-1950)"], "Total_Cost": ["EUR 1 907 944"], "Country": ["Netherlands", "Netherlands", "Netherlands"], "Project_ACR": ["ARTECHNE"], "Technology_Description": "The transmission of \u2018technique\u2019 in art has been a conspicuous \u2018black box\u2019 resisting analysis. The tools of the humanities used to study the transmission of ideas and concepts are insufficient when it comes to understanding the transmission of something as non-propositional and non-verbal as \u2018technique\u2019. The insights of the neurosciences in, for example, the acquisition and transmission of drawing skills are not yet sufficiently advanced to be historically restrictive. However, only in the most recent years, the history of science and technology has turned to how-to instructions as given in recipes. This project proposes to undertake the experimental reconstruction of historical recipes to finally open the black box of the transmission of technique in the visual and decorative arts. Considering \u2018technique\u2019 as a textual, material and social practice, this project will write a long-term history of the theory and practice of the study of \u2018technique\u2019 in the visual and decorative arts between 1500 and 1950. The three central research questions here are: (1) what is technique in the visual and decorative arts, (2) how is technique transmitted and studied, and (3) who is considered expert in technique, and why? This project will make a breakthrough in our understanding of the transmission of technique in the arts by integrating methodologies typical for the humanities and historical disciplines with laboratory work. Also, by providing a history of technique in the arts, this project lays the historical foundations of the epistemologies of conservation, restoration and technical art history precisely at a moment of greatest urgency. The connection between the history of science and technology and the expertise in conservation, restoration and technical art history (in the Ateliergebouw in Amsterdam) this project envisions builds the intellectual infrastructure of a new field of interdisciplinary research, unique in Europe.", "To": ["2020-08-31, ongoing project |"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["648718"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["HUMBOLDT-UNIVERSITAET ZU BERLIN"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["The implementation of the EU employment policies in Germany, Italy and Denmark"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["EUP"], "Technology_Description": "Unemployment is one of the major challenges that the world economy is facing at present. The European Union (EU) is trying to cope with this problem by promoting the flexicurity strategy (Europe 2020: COM(2010) 2020 final). This strategy aims to conciliate the flexibility requested by companies and the social and employment security needed by workers (COM(2007) 359 final). One of its main aspects concerns the relevant role recognized to active and passive labour market policies (active and passive LMPs). At the same time, the flexicurity concept is vague and ambiguous: this aspect brings difficulties in its implementation, and can have negative implications on the level of protection of unemployed people. The research project aims to analyse the legal implementation/adaptation (i./a.) of the flexicurity strategy \u2013 with regard to active and passive LMPs \u2013 in three member states: Germany, Italy and Denmark, that are representative of three different kinds of social security systems in EU, (Continental, Mediterranean and Nordic systems). ", "To": ["2017-05-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-06-01"], "Project_ID": ["654925"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Multicompartmental Designs For Protocells"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["Protoeukaryotes"], "Technology_Description": "Protocells are artificial mimics of cellular systems exhibiting some of the quintessential characteristics of living systems such as compartmentalization, replication and selective exchange of chemical species with the environment. Apart from enabling better understanding about the origin of life, protocells can also be perceived as micromachines which can be programmed to perform functions such as clinical diagnosis, drug delivery, remote sensing, environment detoxification, etc. The range of applications for protocells can be broadened by increasing their structural complexity which would enable complex functions. However, to date the structural complexity of protocellular models has been minimal. Eukaryotic cells are model systems for complexity with compartmentalization into membrane bound organelles interacting through selective exchange of metabolites resulting in complex chemical networks which make possible smart functions such as feedback regulation and homeostasis. No parallel of this hierarchical organization exists in protocell literature. The aim of this proposal is to address this issue by design and construction of multicompartmental protocell models capable of complex functions such as self-regulation, locomotion and light harvesting. The interaction between the various compartments will be enabled by constructing gates across their membranes using stimuli responsive polymers to allow compartments to activate pathways which can affect the function or metabolite level of another compartment, leading to self-regulation of function or metabolite levels in the protocell. It is in this regard that the previous expertise of the applicant (Dr. Pavan Kumar) in constructing gates to control the transport in nanochannels will be applied to the multi-disciplinary and cutting edge field of protocells in which the hosting group at the University of Bristol (under the leadership of Prof.Stephen Mann FRS) has made tremendous progress in the last few years.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["705165"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Quantum Unique Ergodicity and Random Waves on Graphs"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["QUERWG"], "Technology_Description": "The proposal aims to address two important conjectures of Quantum Chaos, Quantum Unique Ergodicity and the Random Wave hypothesis, via the analysis of eigenfunctions of the Laplacian on discrete graphs. It will provide a better understanding of two difficult problems of mathematical physics through an original approach, while developing spectral theory on graphs. The latter has a strong potential of applications in the study of networks, whose understanding is of great importance in the modern world. The expertise of the experienced researcher on analysis on graphs will be ideally complemented by the quantum chaos and ergodic theory specialists of the University of Bristol, to ensure the success of this project.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["703162"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["The impact of recent retrotransposon invasions on the evolution of human neural gene expression"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["Evolutionary Neurogenomics"], "Technology_Description": "Throughout evolution, primate genomes have been under attack by different classes of retrotransposons, retrovirus-derived mobile DNA elements. As a result, an astonishing ~50% of the human genome is derived from many types of retrotransposons. I previously showed that primate-specific retrotransposon invasions are restricted by primate-specific KRAB zinc finger proteins. These findings suggest that through recruitment to thousands of new genomic locations, KRAB zinc finger proteins have become intimately integrated into pre-existing gene regulatory pathways. Retrotransposons are an important source for evolutionary novelties, but the impact of thousands of human-specific retrotransposon-KZNF regulatory modules on the evolution of human gene expression patterns is unknown. There is increasing evidence that retrotransposons become reactivated during neural differentiation, suggesting that neuronal gene-regulatory networks may be extra sensitive to retrotransposon insertions. Furthermore, new retrotransposon insertions may hold clues to the mechanism of human disease: Even when retrotransposons are efficiently silenced in health, they may become aberrantly activated by changes in DNA methylation observed in neurological diseases and cancer. Using a previously established human and non-human primate stem cell cortical neuron differentiation assay, I will identify, validate and functionally test neurodevelopmental genes that have come under the control of retrotransposons. This will address the impact of recent waves of retrotransposon insertions on the evolution of human neural gene expression patterns and opens up the exploration of how new retrotransposon insertions may be correlated to human neurological disorders. The Marie Sk\u0142odowska-Curie individual fellowship will provide the opportunity to establish my research group in Europe and re-integrate in Dutch and EU networks, as well as allow me to achieve my professional development training goals.", "To": ["2017-05-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-06-01"], "Project_ID": ["659193"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Optimizing for Happiness in Personal Finance"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["OHPF"], "Technology_Description": "In this project, we will (1) investigate the ability to use the log of emotional states captured with wearable trackers for improving affective forecasting abilities of people, (2) build a tool for managing personal finance that integrates prediction analytics, and (3) evaluate if accurate expectations about purchases increase happiness of individuals. ", "To": ["2017-09-29, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-30"], "Project_ID": ["655723"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Brain growth under social pressure: mathematical modelling of brain growth when individuals face social challenges"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SocialBrain"], "Technology_Description": "Growing and maintaining a large brain entails substantial energetic costs. A large brain can evolve if costs are compensated by benefits from associated cognitive abilities. Leading hypotheses for brain evolution consider benefits arising from the solution of ecological and social problems. However, progress has been hindered by the unavailability of mathematical theory generating testable hypotheses from known causes.", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["701464"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Efficient Spin-Photon Coupling in the Solid-State"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ESPCSS"], "Technology_Description": "The efficient coupling of a single electron spin to a single photon would represent a major milestone in our technological progress, and would lead to revolutionary advancements in communication and computation technologies exploiting quantum mechanical phenomena. Recently nano-scale `domes' of semiconductor known as quantum dots have emerged as the leading platform upon which this goal can be achieved; they can host localised electrons, and around them micro `pillars' can be grown which serve to channel photon emission. The catch, however, is that these are solid-state systems, and a quantum dot inevitably interacts with a large perturbing environment. The central question motivating this research is: ", "To": ["2018-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-04-01"], "Project_ID": ["703193"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Generation of prototissues from functional and chemoselective protocells"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["Smart Protocells"], "Technology_Description": "Protocells are micro-compartments able to perform or mimic primitive biological functions of real cells. Because of this, they are proposed as stepping-stones towards the understanding of the origin of life on Earth. These \u201csmart\u201d microcapsules find potential applications in a variety of fields including medicine, pharmacology, energy conversion, and bioengineering. Progress in these fields will be considerably enhanced by gaining control over communication between protocells, as well as engineering collective functions of protocells.", "To": ["2019-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-02-01"], "Project_ID": ["701876"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["Democratization through Education? The role of education in strengthening civil agency and voice in Sub-Saharan Africa. (Case study: Uganda)"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["EDU-DEM"], "Technology_Description": "EDU-DEM advances our understanding of the role of education in fostering democratization processes in sub-Saharan Africa from the bottom up. Education has been long treated as an area of development programming that is separate from strengthening civil society formation and democratization processes. We still face several knowledge gaps in existing research on how education increases the agency of the wider civil sphere. This void is striking and it is here where EDU-DEM makes an innovative contribution to existing debates. In doing so, EDU-DEM will 1) explore the correlations between educational attainment and civil society characteristics and agency; 2) assess how formal and non-formal education systems and programmes increase the attention to and comprehension of local politics; 3) identify innovative, multi-scalar and context-specific approaches to nurture democratization processes through education.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["702880"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["CO2 LOSS FROM STREAMS IN EUROPEAN KARST SYSTEMS"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["EURO-KARST"], "Technology_Description": "The proposed study aims to elucidate novel aspects about carbon cycling within European karstic watersheds, via stable isotope and flux determinations of dissolved and particulate carbon. Rivers situated in karst bedrock are thought to emit significant quantities of CO2, and due to their large combined surface areas and the abundance of karst terrains worldwide, these features play a crucial but as yet unclear role in the global carbon cycle. The projected work will address this lack of information through the innovative use of stable isotopes, together with the modeling of CO2 evasion and simultaneous flux determinations of dissolved and particulate riverine carbon. The rivers of study are located in Bavaria, Germany, and are tributaries of the Rhine River in a prominent karst terrain of the Franconian Alb. For comparison, a watershed situated in silicate bedrock, the Uhl\u00ed\u0159sk\u00e1 Basin in the Czech Republic, will also be investigated. The research findings will reduce uncertainties in the global carbon budget, and clarify linkages between carbon cycling and climate change. This is an important topic for policymakers in Europe, given the political and economic impacts of global warming.", "To": ["2019-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-02-01"], "Project_ID": ["706088"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 242 929,80"], "Project_Title": ["Duality For Logic On Words"], "Total_Cost": ["EUR 242 929,80"], "Country": ["Netherlands"], "Project_ACR": ["DFLOW"], "Technology_Description": "Duality For Logic on Words (DFLOW)", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["655941"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["Deep learning and Bayesian inference for medical imaging"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["DeeBMED"], "Technology_Description": "Diseases characteristic for modern western civilization, such as cancer, diabetes or cardiovascular disorders, lead to millions of deaths per year in the European Union. In order to decrease this enormous quantity, medical imaging should be widely available at early diagnostics and every stage of a therapy. Nowadays, there are various diagnostics techniques including CT, PET, MRI, however, analysis of a medical image is time-consuming and expensive. Development of new effective automatic tool for medical imaging will appear a new strategy in highly specific control of incidences and disease progression. The aim of the DeeBMED project is to develop powerful automatic medical imaging tool that can cope with main problems associated with complex images like medical scans: multimodality of data distribution, large number of dimension and small number of examples, small amount of labeled data, multi-source learning, and robustness to transformations. In this project I will propose a probabilistic framework that combines different deep neural networks (DNN), such as feedforward nets, convolutional nets, Gaussian processes. I will apply DNN to model probabilistic relationships among a medical scan, a disease label, and hidden variables representing latent factors in data. In the case of a small sample size DNN are prone to overfitting. A possible remedy for that is Bayesian learning, however, it is still challenging how to apply it to DNN. In this project I will use various approaches: modelling weights uncertainty, Dropout, Bayesian Distillation. As the result I predict identification of the first highly effective medical imaging analysis tool that in the future will be widely used by radiologists in medical institutes in the whole EU. Novel automation will drastically reduce time and costs of analysis and provide more accessible diagnostics. The project will be carried out at the University of Amsterdam, under the supervision of Prof. Max Welling.", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["702666"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["KING'S COLLEGE LONDON"], "EU_Contribution": ["EUR 269 857,80"], "Project_Title": ["Valuing Innovation Options and Policy Flexibility Under Uncertainty"], "Total_Cost": ["EUR 269 857,80"], "Country": ["United Kingdom"], "Project_ACR": ["INNOVATIONOPTIONS"], "Technology_Description": "This proposal consists of a two-year outgoing phase (1.5 years at MIT and 6-month secondment at LUISS U. in Italy) and one-year re-integration phase at King\u2019s College London. Following advanced innovation training, it aims to develop new ideas and frameworks based on real options theory to appraise innovation options and policy flexibility. Besides training/development and dissemination, the proposal will examine two research themes: ", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-08-01"], "Project_ID": ["653413"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["KING'S COLLEGE LONDON", "KING'S COLLEGE LONDON"], "EU_Contribution": ["EUR 149 761"], "Project_Title": ["Commercialisation of new miniaturised, automated robots for high throughput training and assessment of dexterity in rats and mice."], "Total_Cost": ["EUR 149 761"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["Miniature Robots"], "Technology_Description": "The invention: We have developed new, cost-effective miniature robots using 3D printers and customised electronics and software. Large numbers of robots can run in parallel unattended for 24 hours a day, 7 days a week. These robots can be adapted for a variety of applications in industry and research. In this Proof of Concept phase we will begin commercialisation of one of our robots.", "To": ["2017-12-31, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2015 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-07-01"], "Project_ID": ["713410"], "Call_for_Proposal": ["ERC-2015-PoC"]}, -{"Partners": ["KING'S COLLEGE LONDON", "KING'S COLLEGE LONDON"], "EU_Contribution": ["EUR 1 999 776"], "Project_Title": ["REACH: Risk, Resilience, Ethnicity and AdolesCent Mental Health"], "Total_Cost": ["EUR 1 999 776"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["REACH"], "Technology_Description": "The overarching aim of REACH is to examine groundbreaking questions on the developmental origins of psychosis in migrant and minority ethnic populations using a highly innovative accelerated cohort study of adolescents, to be conducted in south London (UK). It has been known for over 50 years that the incidence of psychotic disorders is high in many migrant and minority ethnic groups across many countries. Our seminal study (AESOP) on this, for example, found that incidence rates were 3 to 6 times higher in black Caribbean and black African populations in the UK than in the white British. There have, however, been no public health initiatives specifically designed to tackle this problem \u2013 this is a public health tragedy. In part this inaction is due to a limited understanding of why rates of disorder are elevated. This points to an urgent need for research that can shed light on why the incidence of psychosis is so high in some populations and, more importantly, provide information on how and when to intervene to reduce risk. In seeking to do this, REACH will break new ground. To achieve these aims, REACH will use highly innovative methods to recruit, assess and follow at one and two years 3 overlapping school-based cohorts of adolescents aged 11-12, 12-13 and 13-14 years (total sample, 2,760; 552 of whom will be assessed more intensively). Collection of data on a) psychotic and other experiences of emotional distress, b) socio-environmental risk and, uniquely, protective factors, and c) psychological and biological (HPA axis related) mechanisms, will enable REACH to examine cutting edge questions about the developmental origins of psychosis. REACH is an ambitious study that, critically, seeks to explain (not just document) ethnic differences and in doing so provide concrete proposals for prevention strategies and interventions to reduce risk of psychosis and other poor mental health outcomes during adolescence, a key developmental stage, in diverse ethnic groups.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["648837"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["LUNDS UNIVERSITET", "LUNDS UNIVERSITET", "LAVISION GMBH"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Frequency Recognition Algorithm for Multiple Exposures"], "Total_Cost": ["EUR 150 000"], "Country": ["Sweden", "Sweden", "Germany"], "Project_ACR": ["FRAME"], "Technology_Description": "This proof of concept (PoC) project seeks to explore the possibility of commercializing an optical imaging instrument with the unique ability of permitting a single detector to acquire and store several images simultaneously. This new concept, which is named Frequency Recognition Algorithm for Multiple Exposures (FRAME), employs an \"image-coding\" strategy, where different exposures are given a unique structural \u201ccode\u201d. Thanks to this novel coding approach, the camera sensor may be exposed to light several times before readout is necessary \u2013 a completely new feature within the field of optical imaging. ", "To": ["2017-05-31, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2015 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-06-01"], "Project_ID": ["692987"], "Call_for_Proposal": ["ERC-2015-PoC"]}, -{"Partners": ["KATHOLIEKE UNIVERSITEIT LEUVEN", "ECOLE NORMALE SUPERIEURE", "RUHR-UNIVERSITAET BOCHUM", "ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE", "UNIVERSITY OF BRISTOL", "CRYPTOEXPERTS SAS", "NXP SEMICONDUCTORS BELGIUM NV", "TECHNISCHE UNIVERSITEIT EINDHOVEN"], "EU_Contribution": ["EUR 3 893 199,84"], "Project_Title": ["European Integrated Research Training Network on Advanced Cryptographic Technologies for the Internet of Things and the Cloud"], "Total_Cost": ["EUR 3 893 199,84"], "Country": ["Belgium", "France", "Germany", "United Kingdom", "United Kingdom", "France", "Belgium", "Netherlands"], "Project_ACR": ["ECRYPT-NET"], "Technology_Description": "The goal of this ETN is to develop advanced cryptographic techniques for the Internet of Things and the Cloud and to create implementations that offer a high level of security and increased usability, for a wide range of physical computation platforms. The ITN will equip a group of 15 early stage researchers with a set of interdisciplinary skills combining mathematics, computer science and electrical engineering that will allow them to create advanced cryptographic solutions that will be available for commercial applications. The 8 partners (including 2 companies) are leading research teams in the area of applied cryptology with a strong track record of collaboration; it is complemented by 6 partner organisations from industry (including 2 SMEs).The training from the ERSs will be guided by a personal development plan. A central component is training by research supported by an intensive program of workshops, summer schools, seminars, research visits, and secondments. The training will be complemented with transferable skills that also support the transfer of research to an industrial context. The management structure of the project is built on a pro-active approach with responsibilization of the fellows. The dissemination and outreach of the project activities target a broad range of stakeholders. The ITN contributes to the ERA by helping to overcome the fragmentation in the area of applied cryptology. The research supports the trust and security component of the Digital Agenda for Europe and responds to the growing attention of EU policy makers for societal needs related to privacy and cybersecurity. The societal relevance and timeliness of this research has been emphasized by revelations made by Snowden, that provide clear evidence of mass surveillance by nation states and of serious weaknesses of our current infrastructure. An essential component of a response to these revelations consists a broad deployment of advanced and innovative cryptographic techniques.", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2015-03-01"], "Project_ID": ["643161"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["COVENTRY UNIVERSITY", "UNIVERSITY OF SOUTHAMPTON", "HOCHSCHULE MAGDEBURG-STENDAL", "DANMARKS TEKNISKE UNIVERSITET"], "EU_Contribution": ["EUR 126 000"], "Project_Title": ["Knowledge Exchange for Efficient Passage of Fishes in the Southern Hemisphere"], "Total_Cost": ["EUR 135 000"], "Country": ["United Kingdom", "United Kingdom", "Germany", "Denmark"], "Project_ACR": ["KEEPFISH"], "Technology_Description": "The decline of freshwater fish biodiversity is proceeding at an alarming and persistent rate. Given that most fish must undertake some form of migration in order to complete their life-cycle, of particular concern is the proliferation of hydropower schemes that block migration routes, as well as a variety of other barriers such as weirs and culverts. Several locations in the southern hemisphere are among the major global hotspots of hydropower development. They are also home to some of the least studied fish communities in the world. Mitigation measures for fish passage have traditionally relied on designs developed for strong swimming fishes of the northern hemisphere. These designs are ineffective for generally smaller, relatively weak swimming fish, such as those found in temperate regions of the southern hemisphere, but there is very little understanding of the mechanisms involved. This innovative project represents the first systematic attempt to bring together world-leading practitioners from Europe with biologists, engineers and stakeholders from the southern hemisphere in an effort to exchange knowledge and construct a shared vision for fish passage science and policy. This will be achieved through systematic review, expert consultation, ecological modelling, training programmes, networking and stakeholder engagement using a novel combination of approaches. The outcomes will include: high quality journal publications; a summer school; a set of funding bids based on a co-constructed research strategy; and a model predicting fish passage for species of the southern hemisphere. The project\u2019s key performance indicators will include: number of publications on fish passage in the southern hemisphere; uptake of robust methods in fish passage research; corresponding citations; metrics indicating public awareness (online activity, readership of popular publications, number of people reached in public engagement events); and policy citations.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["690857"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 174 864,60"], "Project_Title": ["Neither Dwarf nor Leviathan: Explaining Territorial and Functional Variation in State Capacity"], "Total_Cost": ["EUR 174 864,60"], "Country": ["Netherlands"], "Project_ACR": ["STATE CAPACITY"], "Technology_Description": "Citizens live longer, happier lives where states are able to perform their core functions effectively. Even though weak states have received considerable attention from scholars and policy-makers, the concept of state weakness has remained under-theorized. The shortcomings of current conceptualizations are revealed by mounting empirical evidence that (1) state capacity does not extend homogeneously across national territories and (2) that a state\u2019s capacity to control and coerce citizens is distinct from its capacity to care for them by providing education and public health. Previous work mostly assumed that the reason why states do not exercise coercion and care throughout the territory is simply their inability to do so. This perspective, however, cannot explain why states invest more in building capacity in some regions than in others, or why coercive and caring capacity are geographically uneven. To understand this, it is crucial to acknowledge that states in the developing world can and do invest in building capacity, but are also confronted with the need to ration resources.", "To": ["2018-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-07-01"], "Project_ID": ["656361"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI DI TRIESTE"], "EU_Contribution": ["EUR 262 269"], "Project_Title": ["Enabling motor control after a spinal cord injury through nanoscaled electrical"], "Total_Cost": ["EUR 262 269"], "Country": ["Italy"], "Project_ACR": ["EPI_nanoSTIM"], "Technology_Description": "A spinal cord injury (SCI) has consistent social costs, due to dramatic and disabling consequences and a high incidence on the youngest and most productive population, which can hardly be alleviated by the very few and controversial therapeutic treatments. In a recent case report, epidural electrostimulation combined with an intense training enabled some highly variable conscious motor control of legs in four motor complete spinal cord injured volunteers. The aim of understanding the mechanisms behind these improvements can help define more effective pharmacological and electrical stimulating protocols with breakthrough technology to restore functions after a SCI. Experiments will be performed on adult rats, with an experimental SCI closer to human chronic lesions, on which I will apply the novel enabling protocol with epidural electrostimulation associated with an intense motor training. Outcome will be evaluated with innovative combinations of electromyographic and kinematic assessments of locomotion and standing posture, in vivo terminal intracellular recordings from lumbar motoneurons and histological examination of spared axons across the lesion. Then, I will employ carbon nanotubes to devise nanostructured innovative stimulation arrays for a more specific and focussed epidural stimulation to enhance recovery. ", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["661452"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITA POLITECNICA DELLE MARCHE", "STUDIO ASSOCIATO GAIA SNC DEI DOTTORI ANTONIO SARA E MARTINA MILANESE", "UBICA SRL", "BOGAZICI ULUSLARARASI EGITIM DANISMANLIK MERKEZI VE TICARET LIMITED SIRKETI", "DIVERS ALERT NETWORK EUROPE FOUNDATION", "STICHTING NHTV INTERNATIONALE HOGESCHOOL BREDA", "NOORDWES-UNIVERSITEIT", "THE COLLEGE OF EXPLORATION", "DIVERS ALERT NETWORK SOUTHERN AFRICA", "BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY"], "EU_Contribution": ["EUR 1 611 000"], "Project_Title": ["Green Bubbles RISE for sustainable diving"], "Total_Cost": ["EUR 1 620 000"], "Country": ["Italy", "Italy", "Italy", "Turkey", "Malta", "Netherlands", "South Africa", "United States", "South Africa", "United States"], "Project_ACR": ["GreenBubbles"], "Technology_Description": "Recreational SCUBA divinga has become a mass leisure activity engaging millions of divers worldwide. The diving industry generates large direct and indirect revenues for coastal communities and Marine Protected Areas (MPAs). Other benefits linked to diving include the promotion of ocean stewardship, contribution to scientific research, fostering social inclusion and personal development. Yet, diving has also negative impacts, due to damage or disturbance of marine habitats and organisms and to conflicts with local communities for the access to/use of the same resources, equity issues, or cultural clashes. These aspects clearly relate to the three pillars of sustainability, covering environmental, economic and social dimensions and can only be addressed by a systemic approach.", "To": ["2018-12-31, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other", "Other", "Higher or Secondary Education Establishments"], "From": ["2015-01-01"], "Project_ID": ["643712"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["UNIVERSITA CATTOLICA DEL SACRO CUORE", "STICHTING VU", "BETTER VALUE HEALTHCARE LTD", "ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM", "UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA", "LINKCARE HEALTH SERVICES SL", "DEBRECENI EGYETEM", "Myriad Genetics Srl", "EUROPEAN PUBLIC HEALTH ASSOCIATION", "STICHTING VUMC", "MOUNT SINAI SCHOOL OF MEDICINE", "ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING MCGILL UNIVERSITY"], "EU_Contribution": ["EUR 792 000"], "Project_Title": ["Personalized PREvention of Chronic DIseases"], "Total_Cost": ["EUR 792 000"], "Country": ["Italy", "Netherlands", "United Kingdom", "Netherlands", "Italy", "Spain", "Hungary", "Italy", "Netherlands", "Netherlands", "United States", "Canada"], "Project_ACR": ["PRECeDI"], "Technology_Description": "The aim of the Personalized pREvention of Chronic DIseases consortium (PRECeDI) is to provide high-quality, multidisciplinary knowledge through training and research in Personalized Medicine (PM), with specific reference to prevention of chronic diseases. There is a large consensus that PM is a driver of innovation for research and health care, and also for the health care system and industry as a whole. In order to harness the potential of this new concept, the PRECeDI consortium provides a cohesive framework for training staff from academic and non-academic (NA) institutions on research topics related to PM, with specific reference to the prevention of chronic diseases where there is a lack of substantial evidence, though the potential is huge. The acquisition of skills from staff will come from dedicated secondments aimed at training on research topics not available at the home institutions, and attendance to courses, workshops, seminars, conferences. The goal of secondment is to enable staff to make informed decisions for appropriately serve health care systems, new biotech industries and policy makers at the dawn of the post-genomic era", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-01-01"], "Project_ID": ["645740"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN", "JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN"], "EU_Contribution": ["EUR 148 750"], "Project_Title": ["Commercialization of an innovative tomographic reconstruction algorithm (Super-sampling SART)for various geometry setups"], "Total_Cost": ["EUR 148 750"], "Country": ["Germany", "Germany"], "Project_ACR": ["SuperSART"], "Technology_Description": "In this proposal, we would like to advance our high quality and highly flexible multi-purpose three-dimensional tomographic reconstruction algorithm from a state of the art research tool to an innovative commercial software product. Transmission tomography uses N-1 dimensional images to reconstruct an N-dimensional object. It is applicable on a multitude of applications ranging from scientific to industrial level. Our implementation has already proven its superior image reconstruction capabilities for incomplete and low signal-to-noise ratio electron tomography and X-ray microscopy data against the established reconstruction algorithms. In addition, the reconstruction time is reduced to between 50% and 90% compared to other reconstruction methods. Thus, it offers crucial advantages for multi-dimensional image visualization and interpretation, in particular for quantitative information extraction.", "To": ["2017-06-30, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2015 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["693521"], "Call_for_Proposal": ["ERC-2015-PoC"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "KAROLINSKA INSTITUTET", "KING'S COLLEGE LONDON", "UNIVERSITE DE LIEGE", "GENOME RESEARCH LIMITED", "KARLSRUHER INSTITUT FUER TECHNOLOGIE", "RIKEN THE INSTITUTE OF PHYSICAL AND CHEMICAL RESEARCH", "CONSORCI INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER", "BGI EUROPE INSTITUTE FOND"], "EU_Contribution": ["EUR 3 758 916,75"], "Project_Title": ["Computational and functional annotation of genomic elements during development of the model vertebrate zebrafish"], "Total_Cost": ["EUR 3 758 916,75"], "Country": ["United Kingdom", "United Kingdom", "Germany", "Sweden", "United Kingdom", "Belgium", "United Kingdom", "Germany", "Japan", "Spain", "Denmark"], "Project_ACR": ["ZENCODE-ITN"], "Technology_Description": "The recent explosion of next generation sequencing (NGS) data has caught Europe unprepared and led to a critical shortage of computational biology expertise. As NGS methods are expected to become pervasive from basic science to personalised medicine there is an urgent need for highly skilled young scientists trained in both computational biology and experimental wet lab biology. Our network addresses this important problem of the postgenomic era. We aim to provide multi-disciplinary skills for a solid foundation in computational biology and developmental genomics. Developmental genomics is central to understanding of ontogeny and many genetic and congenital anomalies, but was outside the scope of the landmark ENCODE and FANTOM projects. ENCODE highlighted the need for an in vivo vertebrate model that enables high throughput in vivo functional testing of hypotheses generated from genome scale annotation. Zebrafish is an ideal model for extending the scope of genomics to vertebrate development. We aim to comprehensively annotate functional elements, decipher genomic codes of transcription, as well as coding and non-coding gene function during development and enhance zebrafish as an attractive developmental, comparative and disease model. The participants include 7 non-academic members (2 of which are beneficiaries), major zebrafish genomics laboratories, eminent computational biologists and world class genomics technology experts active in FANTOM and ENCODE. The training program involves 15 ESRs, more than 40 intersectoral and interdisciplinary secondments totalling 19 months, 7 training courses and 2 workshops/conferences. The main outcome of this programme is a cohort of researchers with computational, experimental laboratory and transferable skills ready to further their career in academia, public health and the private sector.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Other"], "From": ["2015-01-01"], "Project_ID": ["643062"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["HELMHOLTZ ZENTRUM FUR OZEANFORSCHUNG KIEL", "LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN", "INSTITUT DE PHYSIQUE DU GLOBE DE PARIS", "UNIVERSITA DEGLI STUDI DI MILANO", "CESKA ZEMEDELSKA UNIVERZITA V PRAZE", "JOANNEUM RESEARCH FORSCHUNGSGESELLSCHAFT MBH", "USTAV VIED O ZEMI SLOVENSKEJ AKADEMIE VIED", "THERMO FISHER SCIENTIFIC (BREMEN) GMBH", "JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN", "THE HEBREW UNIVERSITY OF JERUSALEM", "CESKA GEOLOGICKA SLUZBA", "INSTYTUT PALEOBIOLOGII IM.ROMANA KOZLOWSKIEGO POLSKIEJ AKADEMII NAUK", "TECHNISCHE UNIVERSITAET GRAZ", "KOBENHAVNS UNIVERSITET", "JR-AQUACONSOL GMBH"], "EU_Contribution": ["EUR 3 749 331,24"], "Project_Title": ["Brachiopods As SEnsitive tracers of gLobal marINe Environment: Insights from alkaline, alkaline Earth metal, and metalloid trace element ratios and isotope systems"], "Total_Cost": ["EUR 3 749 331,24"], "Country": ["Germany", "Germany", "France", "Italy", "Czech Republic", "Austria", "Slovakia", "Germany", "Germany", "Israel", "Czech Republic", "Poland", "Austria", "Denmark", "Austria"], "Project_ACR": ["BASE-LiNE Earth"], "Technology_Description": "Data on seawater composition since the start of the Phanerozoic eon ~540 million years ago provide essential information for understanding long-term chemical processes of socio-economic dimension like the evolution of life, land-ocean interaction, atmospheric chemistry, ecosystem adaptation to climate change, oceanic trace metal cycling, and for applied geological processes like the formation of submarine energy resources. Although partly known this knowledge is still limited pending new methodical prospects and innovative analytical techniques. Following this approach, the proposed ETN \"BASE-LiNE Earth\" will train early stage researchers (ESRs) who will extend the knowledge of the complex and long-term Phanerozoic seawater history by the determination of original proxy information preserved in reliable ancient geological archives using cutting edge technologies and experimental approaches. In order to amplify this process the ESRs will be exposed to academic and non-academic high-tech institutions linking biogeochemical research and training in biology, ecology, geochemistry as well as chemical analytics to engineering and cutting edge analytical instrumentation. Multi- and interdisciplinary environments will expose our ESRs to highly demanded transferable skills increasing their employability when it comes to job application. \"BASE-LiNE Earth\" will offer societally important deliverables like time series of past trace element and isotope cycling and models about ocean material fluxes in and out of the Phanerozoic Ocean. This will be shared in publications, reports and exhibitions. Interactive lecturing material will be offered for education in general and specifically for high school teachers. Through collaboration with high-tech companies the ETN will contribute to establish both, new approaches for the exploration of hydrocarbon reservoirs and innovative and sophisticated analytical instrumentation for trace element and isotope measurements.", "To": ["2018-12-31, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["643084"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["UNIVERSITY OF BRISTOL", "BAUHAUS-UNIVERSITAET WEIMAR", "ARISTOTELIO PANEPISTIMIO THESSALONIKIS", "UNIVERSITA DEGLI STUDI DEL SANNIO", "PANEPISTIMIO PATRON", "CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL", "VCE VIENNA CONSULTING ENGINEERS ZT GMBH", "STIFTELSEN NORGES GEOTEKNISKE INSTITUTT", "UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II.", "HOCHTIEF ENGINEERING GMBH"], "EU_Contribution": ["EUR 909 000"], "Project_Title": ["EXperimental Computational Hybrid Assessment of Natural Gas pipelines Exposed to Seismic Risk"], "Total_Cost": ["EUR 909 000"], "Country": ["United Kingdom", "Germany", "Greece", "Italy", "Greece", "Germany", "Austria", "Norway", "Italy", "Germany"], "Project_ACR": ["EXCHANGE-Risk"], "Technology_Description": "EXCHANGE-Risk is an Intersectoral/International Research and Innovation staff exchange scheme between academia and the industry in Europe and North America focusing on mitigating Seismic Risk of buried steel pipeline Networks that are subjected to ground-imposed permanent deformations. It also aims at developing a Decision Support System for the Rapid Pipeline Recovery to minimize the time required for inspection and rehabilitation in case of a major earthquake. EXCHANGE-Risk involves novel hybrid experimental and numerical work of the soil-pileline system at a pipe, pipeline and network level integrated with innovative technologies for rapid pipe inspection. The outcome of the project is a series of well targeted exchanges between the partners (involving more than 30 early stage and experienced researchers) within a well defined framework of innovation that ensures transfer of knowledge between the academia and the industry, Europe and North America as well wide dissemination of the methodologies and tools developed to the engineering community.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-01-01"], "Project_ID": ["691213"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["CONSIGLIO NAZIONALE DELLE RICERCHE", "THE UNIVERSITY OF SHEFFIELD", "UNIVERSITA DI PISA", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.", "TARTU ULIKOOL", "SCUOLA IMT (ISTITUZIONI, MERCATI, TECNOLOGIE) ALTI STUDI DI LUCCA", "GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER", "KING'S COLLEGE LONDON", "SCUOLA NORMALE SUPERIORE", "AALTO-KORKEAKOULUSAATIO", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "TECHNISCHE UNIVERSITEIT DELFT"], "EU_Contribution": ["EUR 5 000 000"], "Project_Title": ["SoBigData Research Infrastructure"], "Total_Cost": ["EUR 5 917 500"], "Country": ["Italy", "United Kingdom", "Italy", "Germany", "Estonia", "Italy", "Germany", "United Kingdom", "Italy", "Finland", "Switzerland", "Netherlands"], "Project_ACR": ["SoBigData"], "Technology_Description": "One of the most pressing and fascinating challenges scientists face today, is understanding the complexity of our globally interconnected society. The big data arising from the digital breadcrumbs of human activities promise to let us scrutinize the ground truth of individual and collective behaviour at an unprecedented detail and scale. There is an urgent need to harness these opportunities for scientific advancement and for the social good. The main obstacle to this accomplishment, besides the scarcity of data scientists, is the lack of a large-scale open infrastructure, where big data and social mining research can be carried out.", "To": ["2019-08-31, ongoing project |"], "Meta": [""], "Topic_s": ["INFRAIA-1-2014-2015 - Integrating and opening existing national and regional research infrastructures of European interest"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["654024"], "Call_for_Proposal": ["H2020-INFRAIA-2014-2015"]}, -{"Partners": ["LINKOPINGS UNIVERSITET", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA"], "EU_Contribution": ["EUR 823 500"], "Project_Title": ["PEROVSKITE OPTOELECTRONICS"], "Total_Cost": ["EUR 1 233 000"], "Country": ["Sweden", "United Kingdom", "Italy"], "Project_ACR": ["PEOPLE"], "Technology_Description": "The goal of this project is to develop a lasting collaboration between top class research teams in Europe and China that fosters progress in the broad area of perovskite optoelectronics through progress in materials science, chemistry, device physics, photophysics, and device engineering. This will be realized via a cross-European, trans-continental network. Such a network is required as perovskite opotoelectronics is a research area that requires strong collaborations between researchers with different background. More specifically, the PEOPLE network is intended as a key driver for the development of perovskite optoelectronics. Multiple disciplines need to be involved so that PEOPLE can cover the entire knowledge chain: the design/synthesis of perovskite materials, processing/characterization of perovskite films, photovoltaic applications of perovskites, other emerging optoelectronic devices based on perovskites, device physics and photophysics. The combined expertise in PEOPLE is essential to achieve a transformative impact. This project regroups leading research teams in the domain of perovskite optoelectronics, with complementary expertise, in an attempt to synergise the research effort in this area.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Chiara Andreoli", "Tel.: +3901071781854", "Fax: +39 010 7170817"], "From": ["2016-01-01"], "Project_ID": ["691210"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["BRISTOL NATURAL HISTORY CONSORTIUM", "UNIVERSITY OF BRISTOL", "UNIVERSITY OF THE WEST OF ENGLAND, BRISTOL"], "EU_Contribution": ["EUR 127 855"], "Project_Title": ["Bristol Bright Night"], "Total_Cost": ["EUR 127 855"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom"], "Project_ACR": ["BGCN"], "Technology_Description": "Bristol\u2019s proposal for the Marie Sk\u0142odowska-Curie Researchers\u2019 Night programme takes part across 2014 and 2015. Bristol\u2019s programme for Researchers\u2019 Night has an ambition to involve a wide cross-section of researchers across the city\u2019s two universities centred on the theme \u2018Bristol Bright Night\u2019 highlighting the innovative research undertaken by Bristol-based researchers addressing local and global societal challenges. During the Researchers\u2019 Night the city\u2019s waterfront will be transformed into an Innovation Laboratory giving everyone equal access to ground-breaking research, in particular young and family audiences. Bristol has the advantage of having several world-renowned public venues within a short walk of each other in its historical centre. These will host the Researchers\u2019 Night 2014 and 2015. Additionally, in 2015 special opportunities will be provided for celebrating the 10th anniversary of the Researchers\u2019 Night, and the programme will also benefit from Bristol\u2019s designation as European Green Capital in 2015. Bristol\u2019s programme for Researchers\u2019 Night will focus on environmental science and sustainability research conducted locally and through European projects, particularly by Marie Sk\u0142odowska-Curie (MSC) fellows, however, Bristol\u2019s digital and creative media cluster will also be involved.", "To": ["2015-09-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-NIGHT-2014 - European Researchers' Night (NIGHT)"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["United Kingdom"], "Activity": ["Other", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2014-06-01"], "Project_ID": ["633328"], "Call_for_Proposal": ["H2020-MSCA-NIGHT-2014"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI SALERNO", "UNIVERSITA DEGLI STUDI DI CAGLIARI", "UNIVERSITA DEGLI STUDI DI MILANO", "UNIVERZITA PALACKEHO V OLOMOUCI", "USTAV INFORMATIKY AV CR", "USTAV TEORIE INFORMACE A AUTOMATIZACE AV CR VVI", "TECHNISCHE UNIVERSITAET WIEN", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "UNIVERSITAT DE BARCELONA", "UNIVERSITEIT VAN AMSTERDAM", "UNIVERSITA DEGLI STUDI DELL'INSUBRIA", "UNIVERSITAT AUTONOMA DE BARCELONA", "UNIVERSITAET BERN"], "EU_Contribution": ["EUR 504 000"], "Project_Title": ["Syntax Meets Semantics: Methods, Interactions, and Connections in Substructural logics."], "Total_Cost": ["EUR 580 500"], "Country": ["Italy", "Italy", "Italy", "Czech Republic", "Czech Republic", "Czech Republic", "Austria", "Spain", "Spain", "Netherlands", "Italy", "Spain", "Switzerland"], "Project_ACR": ["SYSMICS"], "Technology_Description": "Substructural logics are formal reasoning systems that refine classical logic by weakening the structural rules in Gentzen sequent calculus.", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["689176"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSITY OF BRISTOL", "WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER", "JOHANNES GUTENBERG-UNIVERSITAT MAINZ", "UNIVERSITEIT UTRECHT", "UNIVERSITA DEGLI STUDI ROMA TRE", "UNIVERSITY OF DURHAM", "UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 3 661 113,24"], "Project_Title": ["Complex RhEologies in Earth dynamics and industrial Processes"], "Total_Cost": ["EUR 3 661 113,24"], "Country": ["France", "United Kingdom", "Germany", "Germany", "Netherlands", "Italy", "United Kingdom", "United Kingdom"], "Project_ACR": ["CREEP"], "Technology_Description": "The CREEP Innovative Training Network is a training and career development platform for early stage researchers (ESRs) in Geodynamics, Mineral Physics, Seismology, Fluid Mechanics, and Materials Sciences. It aims to structure the collaboration in research and doctoral training between 10 leading academic centers in Earth Sciences in Europe: the CNRS (FR), represented by Geosciences Montpellier and the FAST Orsay, the universities of Bristol, Durham and UCL (UK), Munster and Mainz (DE), Roma TRE (IT) and Utrecht (NL), and as a partner organization: ETH (CH), and 11 partner organizations whose activity encompasses a variety of industrial applications of rheology: oil (Baker Hughes, Schlumberger) and chemical industries (AkzoNobel), glass (Schott) and steel (APERAM) producers, and high-technology SMEs (Rockfield, IGEM, GMuG, MP Strumenti, Geospatial Research, Reykjavik Geothermal). ", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-04-01"], "Project_ID": ["642029"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["COOPERACION LATINOAMERICANA DE REDES AVANZADAS", "GEANT LIMITED", "GEANT VERENIGING", "REDE NACIONAL DE ENSINO E PESQUISA", "CORPORACION RED NACIONAL ACADEMICA DE TECNOLOGIA AVANZADA", "CORPORACION RED UNIVERSITARIA NACIONAL", "Consorcio Ecuatoriano para el Desarrollo de Internet Avanzado", "CORPORACION UNIVERSITARIA PARA EL DESARROLLO DE INTERNET AC", "THE UBUNTUNET ALLIANCE FOR RESEARCH AND EDUCATION NETWORKING", "WEST AND CENTRAL AFRICAN RESEARCH AND EDUCATION NETWORK", "ARAB STATES RESEARCH AND EDUCATION NETWORK ASREN GEMEINNUTZIGE GMBH", "CESNET ZAJMOVE SDRUZENI PRAVNICKYCH OSOB", "ETHNIKO DIKTYO EREVNAS TECHNOLOGIAS AE", "SURFnet bv", "COUNCIL FOR SCIENTIFIC AND INDUSTRIAL RESEARCH", "GROUPEMENT D INTERET PUBLIC POUR LERESEAU NATIONAL DE TELECOMMUNICATIONS POUR LA TECHNOLOGIE L ENSEIGNEMENT ET LA RECHERCHE", "NEMZETI INFORMACIOS INFRASTRUKTURA FEJLESZTESI IRODA", "KORMANYZATI INFORMATIKAI FEJLESZTESI UGYNOKSEG", "CARRIBEAN KNOWLEDGE AND LEARNING NETWORK FOUNDATION LIMITED", "NATIONAL INFORMATION TECHNOLOGY CENTER", "TEIN COOPERATION CENTER FOUNDATION"], "EU_Contribution": ["EUR 1 355 972"], "Project_Title": ["Middleware for collaborative Applications and Global vIrtual Communities"], "Total_Cost": ["EUR 1 821 872,50"], "Country": ["Uruguay", "United Kingdom", "Netherlands", "Brazil", "Colombia", "Chile", "Ecuador", "Mexico", "Netherlands", "Ghana", "Germany", "Czech Republic", "Greece", "Netherlands", "South Africa", "France", "Hungary", "Hungary", "Grenada", "Kyrgyzstan", "South Korea"], "Project_ACR": ["MAGIC"], "Technology_Description": "The MAGIC Project seeks to establish a set of agreements for Europe, Latin America and other participating World Regions, aiming at consolidating and completing the building blocks of middleware necessary for the establishment of a marketplace of services and real-time applications for international and inter-continental research groups which facilitates mobility and the work of global science communities. More specifically, the project specific goals are:", "To": ["2017-04-30, closed project"], "Meta": [""], "Topic_s": ["INFRASUPP-7-2014 - e-Infrastructure policy development and international cooperation"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Uruguay"], "Activity": ["Other", "Other", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Other", "Other", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Other", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-05-01"], "Project_ID": ["654225"], "Call_for_Proposal": ["H2020-INFRASUPP-2014-2"]}, -{"Partners": ["ATHINA-EREVNITIKO KENTRO KAINOTOMIAS STIS TECHNOLOGIES TIS PLIROFOFORIAS, TON EPIKOLNONION KAI TIS GNOSIS", "THE UNIVERSITY OF MANCHESTER", "TECHNISCHE UNIVERSITAT DARMSTADT", "INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE", "EUROPEAN MOLECULAR BIOLOGY LABORATORY", "AGROKNOW IKE", "STICHTING LIBER", "UNIVERSITEIT VAN AMSTERDAM", "THE OPEN UNIVERSITY", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "FUNDACION CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III", "THE UNIVERSITY OF SHEFFIELD", "GESIS-LEIBNIZ-INSTITUT FUR SOZIALWISSENSCHAFTEN EV", "ETHNIKO DIKTYO EREVNAS TECHNOLOGIAS AE", "FRONTIERS MEDIA SA", "THE UNIVERSITY OF STIRLING", "UNIVERSITY OF GLASGOW", "BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION"], "EU_Contribution": ["EUR 5 375 535,50"], "Project_Title": ["Open Mining INfrastructure for TExt and Data"], "Total_Cost": ["EUR 6 068 072,50"], "Country": ["Greece", "United Kingdom", "Germany", "France", "Germany", "Greece", "Netherlands", "Netherlands", "United Kingdom", "Switzerland", "Spain", "United Kingdom", "Germany", "Greece", "Switzerland", "United Kingdom", "United Kingdom", "Spain"], "Project_ACR": ["OpenMinTeD"], "Technology_Description": "Recent years witness an upsurge in the quantities of digital research data, offering new insights and opportunities for improved understanding. Text and data mining is emerging as a powerful tool for harnessing the power of structured and unstructured content and data, by analysing them at multiple levels and in several dimensions to discover hidden and new knowledge. However, text mining solutions are not easy to discover and use, nor are they easily combinable by end users. OpenMinTeD aspires to enable the creation of an infrastructure that fosters and facilitates the use of text mining technologies in the scientific publications world, builds on existing text mining tools and platforms, and renders them discoverable and interoperablethrough appropriate registriesand a standards-based interoperability layer, respectively. It supports training of text mining users and developers alike and demonstrates the merits of the approach through several use cases identified by scholars and experts from different scientific areas, ranging from generic scholarly communication to literaturerelated tolife sciences, food and agriculture, and social sciences and humanities. Through its infrastructural activities, OpenMinTeD\u2019s vision is tomake operational a virtuous cycle in which a) primary content is accessed through standardised interfaces and access rules b) by well-documented and easily discoverable text mining services that process, analyse, and annotate text c) to identify patterns and extract new meaningful actionable knowledge, which will be used d) for structuring, indexing, and searching content and, in tandem, e) acting as new knowledge useful to draw new relations between content items and firing a new mining cycle. To achieve its goals, OpenMinTeD brings together different stakeholders, content providers and scientific communities, text mining and infrastructure builders, legal experts, data and computing centres, industrial players, and SMEs.", "To": ["2018-05-31, ongoing project"], "Meta": [""], "Topic_s": ["EINFRA-1-2014 - Managing, preserving and computing with big research data"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Greece"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2015-06-01"], "Project_ID": ["654021"], "Call_for_Proposal": ["H2020-EINFRA-2014-2"]}, -{"Partners": ["BRUNEL UNIVERSITY LONDON", "SIGMA ORIONIS SA", "THE UBUNTUNET ALLIANCE FOR RESEARCH AND EDUCATION NETWORKING", "UNIVERSITA DEGLI STUDI DI CATANIA", "WEST AND CENTRAL AFRICAN RESEARCH AND EDUCATION NETWORK", "KUNGLIGA TEKNISKA HOEGSKOLAN", "DAR ES SALAAM INSTITUTE OF TECHNOLOGY", "KAROLINSKA INSTITUTET", "COUNCIL FOR SCIENTIFIC AND INDUSTRIAL RESEARCH"], "EU_Contribution": ["EUR 1 339 125"], "Project_Title": ["Energising Scientific Endeavour through Science Gateways and e-Infrastructures in Africa"], "Total_Cost": ["EUR 1 339 125"], "Country": ["United Kingdom", "France", "Netherlands", "Italy", "Ghana", "Sweden", "Tanzania", "Sweden", "South Africa"], "Project_ACR": ["Sci-GaIA"], "Technology_Description": "In African Communities of Practice (CoPs), international collaboration and the pursuit of scientific endeavour has faced a major barrier with the lack of access to e-Infrastructures and high performance network infrastructure enjoyed by European counterparts. With AfricaConnect, the proposed AfricaConnect2 and regional developments, this situation is changing rapidly. In the project Teaming-up for exploiting e-Infrastructures' potential to boost RTDI in Africa (eI4Africa) it has been demonstrated clearly that it is possible to develop e-Infrastructures in Africa. It has also been demonstrated clearly that, as with the rest of the world, easy to use web portals, or Science Gateways, are needed to help CoPs to easily access e-Infrastructure facilities and through these collaborate with CoPs across the world. However, a major problem exists: it is very difficult for non-experts to develop Science Gateways and supporting e-Infrastructures. Elements of guides and supporting materials exist but these are either written for different audiences or out of date. This present Coordination and Support Action, called Energising Scientific Endeavour through Science Gateways and e-Infrastructures in Africa (Sci-GaIA), therefore proposes to bring together these materials into clearly structured guides and educational documents that can be used to train and support representatives of NRENs, CoPs and, importantly, Universities to develop Science Gateways and other e-Infrastructures services in Africa. Sci-GaIA plans to work with new and emerging CoPs to develop these exciting technologies, to strengthen e-Infrastructure service provision, especially in terms of open access linked data, and to deliver training and dissemination workshops. This will give a sustainable foundation on which African e-Infrastructures can be developed and be linked to scientific networks across Africa. Importantly, the results of our project will be usable by CoPs in Europe and the rest of the world.", "To": ["2017-04-30, closed project"], "Meta": [""], "Topic_s": ["INFRASUPP-7-2014 - e-Infrastructure policy development and international cooperation"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Other", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2015-05-01"], "Project_ID": ["654237"], "Call_for_Proposal": ["H2020-INFRASUPP-2014-2"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "KING'S COLLEGE LONDON", "HUMBOLDT-UNIVERSITAET ZU BERLIN", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "UNIVERSITAT DE BARCELONA", "AALTO-KORKEAKOULUSAATIO", "DANMARKS TEKNISKE UNIVERSITET", "BAYERISCHE AKADEMIE DER WISSENSCHAFTEN", "CSC-TIETEEN TIETOTEKNIIKAN KESKUS OY", "BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION", "PINTAIL LTD"], "EU_Contribution": ["EUR 4 910 624,48"], "Project_Title": ["The Novel Materials Discovery Laboratory"], "Total_Cost": ["EUR 4 910 624,48"], "Country": ["Germany", "United Kingdom", "Germany", "United Kingdom", "Spain", "Finland", "Denmark", "Germany", "Finland", "Spain", "Ireland"], "Project_ACR": ["NoMaD"], "Technology_Description": "Essentially every new commercial product, be they smart phones, solar cells, batteries, transport technology, artificial hips, etc., depends on improved or even novel materials. Computational materials science is increasingly influential as a method to identify such critical materials for both R&D. Enormous amounts of data, precious but heterogeneous and difficult to access or utilise, are already stored in repositories scattered across Europe. The NoMaD CoE will open new HPC opportunities by enabling access to this data and delivering powerful new tools to search, retrieve and manage it.", "To": ["2018-10-31, ongoing project"], "Meta": [""], "Topic_s": ["EINFRA-5-2015 - Centres of Excellence for computing applications"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Other", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-11-01"], "Project_ID": ["676580"], "Call_for_Proposal": ["H2020-EINFRA-2015-1"]}, -{"Partners": ["COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "FORSCHUNGSZENTRUM JULICH GMBH", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "AGENZIA NAZIONALE PER LE NUOVE TECNOLOGIE, L'ENERGIA E LO SVILUPPO ECONOMICO SOSTENIBILE", "CENTRE EUROPEEN DE RECHERCHE ET DE FORMATION AVANCEE EN CALCUL SCIENTIFIQUE", "INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK", "UNIVERSITA DEGLI STUDI DI TRENTO", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.", "UNIVERSITY OF BATH", "THE CYPRUS INSTITUTE", "CONSIGLIO NAZIONALE DELLE RICERCHE", "UNIVERSITE LIBRE DE BRUXELLES", "BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION"], "EU_Contribution": ["EUR 5 403 491"], "Project_Title": ["Energy oriented Centre of Excellence for computer applications"], "Total_Cost": ["EUR 5 689 521,11"], "Country": ["France", "Germany", "Germany", "Italy", "France", "Poland", "Italy", "Germany", "United Kingdom", "Cyprus", "Italy", "Belgium", "Spain"], "Project_ACR": ["EoCoE"], "Technology_Description": "The aim of the present proposal is to establish an Energy Oriented Centre of Excellence for computing applications, (EoCoE). EoCoE (pronounce \u201cEcho\u201d) will use the prodigious potential offered by the ever-growing computing infrastructure to foster and accelerate the European transition to a reliable and low carbon energy supply. To achieve this goal, we believe that the present revolution in hardware technology calls for a similar paradigm change in the way application codes are designed. EoCoE will assist the energy transition via targeted support to four renewable energy pillars: Meteo, Materials, Water and Fusion, each with a heavy reliance on numerical modelling. These four pillars will be anchored within a strong transversal multidisciplinary basis providing high-end expertise in applied mathematics and HPC.", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["EINFRA-5-2015 - Centres of Excellence for computing applications"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2015-10-01"], "Project_ID": ["676629"], "Call_for_Proposal": ["H2020-EINFRA-2015-1"]}, -{"Partners": ["LUNDS UNIVERSITET", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "CONSORCIO PARA EL DISENO, CONSTRUCCION, EQUIPAMIENTO Y EXPLOTACION DELCENTRO DE LASERES PULSADOS ULTRACORTOS ULTRAINTENSOS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "ELETTRA - SINCROTRONE TRIESTE SCPA", "FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS", "FORSCHUNGSVERBUND BERLIN EV", "GSI HELMHOLTZZENTRUM FUER SCHWERIONENFORSCHUNG Gmbh", "HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF EV", "FUNDACIO INSTITUT DE CIENCIES FOTONIQUES", "MEDZINARODNE LASEROVE CENTRUM", "INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU FIZICA LASERILOR PLASMEI SI RADIATIEI", "FYZIKALNI USTAV AV CR V.V.I", "ASSOCIACAO DO INSTITUTO SUPERIOR TECNICO PARA A INVESTIGACAO E DESENVOLVIMENTO", "LABORATORIO EUROPEO DI SPETTROSCOPIE NON LINEARI", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "WOJSKOWA AKADEMIA TECHNICZNA IM JAROSLAWA DABROWSKIEGO", "POLITECNICO DI MILANO", "STICHTING KATHOLIEKE UNIVERSITEIT", "SCIENCE AND TECHNOLOGY FACILITIES COUNCIL", "UNIVERSITY OF STRATHCLYDE", "UNIVERSIDADE DE COIMBRA", "LATVIJAS UNIVERSITATE", "SZEGEDI TUDOMANYEGYETEM", "STICHTING VU", "VILNIAUS UNIVERSITETAS"], "EU_Contribution": ["EUR 10 000 000"], "Project_Title": ["The Integrated Initiative of European Laser Research Infrastructures"], "Total_Cost": ["EUR 10 000 000,89"], "Country": ["Sweden", "France", "Spain", "France", "Italy", "Greece", "Germany", "Germany", "Germany", "Spain", "Slovakia", "Romania", "Czech Republic", "Portugal", "Italy", "Germany", "Poland", "Italy", "Netherlands", "United Kingdom", "United Kingdom", "Portugal", "Latvia", "Hungary", "Netherlands", "Lithuania"], "Project_ACR": ["LASERLAB-EUROPE"], "Technology_Description": "LASERLAB-EUROPE is the European consortium of major national laser research infrastructures, covering advanced laser science and applications in most domains of research and technology, with particular emphasis on areas with high industrial and social impact, such as bio- and nanophotonics, material analyses, biology and medicine. ", "To": ["2019-11-30, ongoing project"], "Meta": [""], "Topic_s": ["INFRAIA-1-2014-2015 - Integrating and opening existing national and regional research infrastructures of European interest"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-12-01"], "Project_ID": ["654148"], "Call_for_Proposal": ["H2020-INFRAIA-2014-2015"]}, -{"Partners": ["EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH", "OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN", "UNIVERSITE CATHOLIQUE DE LOUVAIN", "INSTITUTE OF NUCLEAR RESEARCH AND NUCLEAR ENERGY - BULGARIAN ACADEMY OF SCIENCES", "RUDER BOSKOVIC INSTITUTE", "FYZIKALNI USTAV AV CR V.V.I", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "STIFTUNG DEUTSCHES ELEKTRONEN-SYNCHROTRON DESY", "JOHANNES GUTENBERG-UNIVERSITAT MAINZ", "KARLSRUHER INSTITUT FUER TECHNOLOGIE", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN", "MAGYAR TUDOMANYOS AKADEMIA WIGNER FIZIKAI KUTATOKOZPONT", "TEL AVIV UNIVERSITY", "FONDAZIONE BRUNO KESSLER", "ISTITUTO NAZIONALE DI FISICA NUCLEARE", "VILNIAUS UNIVERSITETAS", "UNIVERSITETET I BERGEN", "AKADEMIA GORNICZO-HUTNICZA IM. STANISLAWA STASZICA W KRAKOWIE", "LABORATORIO DE INSTRUMENTACAO E FISICA EXPERIMENTAL DE PARTICULAS", "INSTITUT JOZEF STEFAN", "CENTRO DE INVESTIGACIONES ENERGETICAS, MEDIOAMBIENTALES Y TECNOLOGICAS-CIEMAT", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "INSTITUTO DE FISICA DE ALTAS ENERGIAS", "INSTITUTO TECNOLOGICO DE ARAGON", "LUNDS UNIVERSITET", "SCIENCE AND TECHNOLOGY FACILITIES COUNCIL", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "UNIVERSITY COLLEGE LONDON", "UNIVERSITY OF BRISTOL", "UNIVERSITY OF GLASGOW", "THE UNIVERSITY OF LIVERPOOL", "THE UNIVERSITY OF MANCHESTER", "THE UNIVERSITY OF BIRMINGHAM", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "UNIVERSITE DE GENEVE"], "EU_Contribution": ["EUR 10 000 000"], "Project_Title": ["Advanced European Infrastructures for Detectors at Accelerators"], "Total_Cost": ["EUR 12 909 986,73"], "Country": ["Switzerland", "Austria", "Belgium", "Bulgaria", "Croatia", "Czech Republic", "France", "France", "Germany", "Germany", "Germany", "Germany", "Germany", "Hungary", "Israel", "Italy", "Italy", "Lithuania", "Norway", "Poland", "Portugal", "Slovenia", "Spain", "Spain", "Spain", "Spain", "Sweden", "United Kingdom", "United Kingdom", "United Kingdom", "United Kingdom", "United Kingdom", "United Kingdom", "United Kingdom", "United Kingdom", "United Kingdom", "Switzerland", "Switzerland"], "Project_ACR": ["AIDA-2020"], "Technology_Description": "Particle physics is at the forefront of the ERA, attracting a global community of more than 10,000 scientists. With the upgrade of the LHC and the preparation of new experiments, the community will have to overcome unprecedented challenges in order to answer fundamental questions concerning the Higgs boson, neutrinos, and physics beyond the Standard Model. Major developments in detector technology are required to ensure the success of these endeavours. ", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["INFRAIA-1-2014-2015 - Integrating and opening existing national and regional research infrastructures of European interest"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Switzerland"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-05-01"], "Project_ID": ["654168"], "Call_for_Proposal": ["H2020-INFRAIA-2014-2015"]}, -{"Partners": ["INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER", "FUNDACION AZTI - AZTI FUNDAZIOA", "BLUE LOBSTER IT LIMITED", "THE SECRETARY OF STATE FOR ENVIRONMENT, FOOD AND RURAL AFFAIRS", "FONDAZIONE CENTRO EURO-MEDITERRANEO SUI CAMBIAMENTI CLIMATICI", "CONSIGLIO NAZIONALE DELLE RICERCHE", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "STICHTING DELTARES", "ETT SPA", "EUROGOOS", "FLUIDION", "ILMATIETEEN LAITOS", "HELLENIC CENTRE FOR MARINE RESEARCH", "HELMHOLTZ-ZENTRUM GEESTHACHT ZENTRUM FUR MATERIAL- UND KUSTENFORSCHUNG GMBH", "INSTITUTO HIDROGRAFICO", "HAVFORSKNINGSINSTITUTTET", "INSTITUTE OF OCEANOLOGY - BULGARIAN ACADEMY OF SCIENCES", "INTERNATIONAL RESEARCH INSTITUTE OFSTAVANGER AS", "MARIENE INFORMATIE SERVICE MARIS BV", "MARINE INSTITUTE", "NORSK INSTITUTT FOR VANNFORSKNING", "ISTITUTO NAZIONALE DI OCEANOGRAFIA E DI GEOFISICA SPERIMENTALE", "MINISTERIE VAN INFRASTRUCTUUR EN MILIEU", "SLR ENVIRONMENTAL CONSULTING(IRELAND)LIMITED", "SMARTBAY IRELAND", "SVERIGES METEOROLOGISKA OCH HYDROLOGISKA INSTITUT", "SOCIB - CONSORCIO PARA EL DISENO, CONSTRUCCION, EQUIPAMIENTO Y EXPLOTACION DEL SISTEMA DE OBSERVACION COSTERO DE LAS ILLES BALEARS", "SUOMEN YMPARISTOKESKUS", "UNIVERSITA TA MALTA", "UNIVERSITAT POLITECNICA DE CATALUNYA", "VLAAMS INSTITUUT VOOR DE ZEE VZW", "EURO-ARGO ERIC", "DURAND DOMINIQUE, DENIS, FABRICE"], "EU_Contribution": ["EUR 9 998 876,47"], "Project_Title": ["Joint European Research Infrastructure network for Coastal Observatory \u2013 Novel European eXpertise for coastal observaTories"], "Total_Cost": ["EUR 9 998 876,47"], "Country": ["France", "Spain", "United Kingdom", "United Kingdom", "Italy", "Italy", "France", "Spain", "Netherlands", "Italy", "Belgium", "France", "Finland", "Greece", "Germany", "Portugal", "Norway", "Bulgaria", "Norway", "Netherlands", "Ireland", "Norway", "Italy", "Netherlands", "Ireland", "Ireland", "Sweden", "Spain", "Finland", "Malta", "Spain", "Belgium", "France", "Norway"], "Project_ACR": ["JERICO-NEXT"], "Technology_Description": "The coastal area is the most productive and dynamic environment of the world ocean with significant resources and services for mankind.", "To": ["2019-08-31, ongoing project |"], "Meta": [""], "Topic_s": ["INFRAIA-1-2014-2015 - Integrating and opening existing national and regional research infrastructures of European interest"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-09-01"], "Project_ID": ["654410"], "Call_for_Proposal": ["H2020-INFRAIA-2014-2015"]}, -{"Partners": ["STICHTING ASTRON, NETHERLANDS INSTITUTE FOR RADIO ASTRONOMY", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "ISTITUTO NAZIONALE DI ASTROFISICA", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "JOINT INSTITUTE FOR VERY LONG BASELINE INTERFEROMETRY AS A EUROPEAN RESEARCH INFRASTRUCTURE CONSORTIUM (JIV-ERIC)", "JOINT INSTITUTE FOR V.L.B.I. IN EUROPE (J.I.V.E.)", "INSTITUTO NACIONAL DE TECNICA AEROESPACIAL ESTEBAN TERRADAS", "THE UNIVERSITY OF EDINBURGH", "RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG", "THE OPEN UNIVERSITY", "FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG", "STICHTING VU", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "UNIVERSITEIT VAN AMSTERDAM", "UNIVERSIDAD DE GRANADA", "STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN", "INSTITUT D'ESTUDIS ESPACIALS DE CATALUNYA FUNDACION", "INSTITUTO DE FISICA DE ALTAS ENERGIAS", "UNIVERSIDAD COMPLUTENSE DE MADRID", "ISTITUTO NAZIONALE DI FISICA NUCLEARE", "SCIENCE AND TECHNOLOGY FACILITIES COUNCIL", "STIFTUNG DEUTSCHES ELEKTRONEN-SYNCHROTRON DESY", "SURFnet bv", "GTD SISTEMAS DE INFORMACION SA"], "EU_Contribution": ["EUR 14 991 194"], "Project_Title": ["Astronomy ESFRI and Research Infrastructure Cluster"], "Total_Cost": ["EUR 14 991 194"], "Country": ["Netherlands", "France", "Italy", "United Kingdom", "Netherlands", "Netherlands", "Spain", "United Kingdom", "Germany", "United Kingdom", "Germany", "Netherlands", "France", "Netherlands", "Spain", "Netherlands", "Spain", "Spain", "Spain", "Italy", "United Kingdom", "Germany", "Netherlands", "Spain"], "Project_ACR": ["ASTERICS"], "Technology_Description": "ASTERICS (Astronomy ESFRI & Research Infrastructure Cluster) aims to address the cross-cutting synergies and common challenges shared by the various Astronomy ESFRI facilities (SKA, CTA, KM3Net & E-ELT). It brings together for the first time, the astronomy, astrophysics and particle astrophysics communities, in addition to other related research infrastructures. The major objectives of ASTERICS are to support and accelerate the implementation of the ESFRI telescopes, to enhance their performance beyond the current state-of-the-art, and to see them interoperate as an integrated, multi-wavelength and multi-messenger facility. An important focal point is the management, processing and scientific exploitation of the huge datasets the ESFRI facilities will generate. ASTERICS will seek solutions to these problems outside of the traditional channels by directly engaging and collaborating with industry and specialised SMEs. The various ESFRI pathfinders and precursors will present the perfect proving ground for new methodologies and prototype systems. In addition, ASTERICS will enable astronomers from across the member states to have broad access to the reduced data products of the ESFRI telescopes via a seamless interface to the Virtual Observatory framework. This will massively increase the scientific impact of the telescopes, and greatly encourage use (and re-use) of the data in new and novel ways, typically not foreseen in the original proposals. By demonstrating cross-facility synchronicity, and by harmonising various policy aspects, ASTERICS will realise a distributed and interoperable approach that ushers in a new multi-messenger era for astronomy. Through an active dissemination programme, including direct engagement with all relevant stakeholders, and via the development of citizen scientist mass participation experiments, ASTERICS has the ambition to be a flagship for the scientific, industrial and societal impact ESFRI projects can deliver.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["INFRADEV-4-2014-2015 - Implementation and operation of cross-cutting services and solutions for clusters of ESFRI and other relevant research infrastructure initiatives"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Netherlands"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-05-01"], "Project_ID": ["653477"], "Call_for_Proposal": ["H2020-INFRADEV-1-2014-1"]}, -{"Partners": ["STICHTING NATURALIS BIODIVERSITY CENTER", "JUSTUS-LIEBIG-UNIVERSITAET GIESSEN", "MUZEUL NATIONAL DE ISTORIE NATURALA GRIGORE ANTIPA", "UNIVERSITEIT UTRECHT", "GIMARIS", "BRUNEL UNIVERSITY LONDON", "UNIVERSITY OF BRISTOL", "THE UNIVERSITY OF READING", "UNIVERSITATEA DIN BUCURESTI", "UNIVERSITAET BREMEN"], "EU_Contribution": ["EUR 3 784 088,60"], "Project_Title": ["Drivers of Pontocaspian biodiversity RIse and DEmise"], "Total_Cost": ["EUR 3 784 088,60"], "Country": ["Netherlands", "Germany", "Romania", "Netherlands", "Netherlands", "United Kingdom", "United Kingdom", "United Kingdom", "Romania", "Germany"], "Project_ACR": ["PRIDE"], "Technology_Description": "Since the 1930s, the unique endemic aquatic biota of the Caspian-Black Sea region is facing a biodiversity crisis as it is severely affected by anthropogenic activities such as habitat destruction, invasive species and pollution. Understanding long-term natural biotic and abiotic drivers of lake system change and biotic response to perturbations in the past 2 Ma \u2013 i.e. gradual, rapid and/or threshold responses \u2013 is absolutely necessary to assess the current response of Pontocaspian biota to rising natural- and human-induced perturbations. The Pontocaspian example mirrors the complex global ecological and biodiversity challenge due to Global Change. This challenge can only be addressed through an integrated cross-disciplinary research involving climate, earth- and bio-sciences. PRIDE (Pontocaspian biodiversity RIse and DEmise) is a fully integrated academia-industry training network of scientists with complementary cutting-edge competences. PRIDE focuses on the evolution of Pontocaspian biota over the past 2 million years. The extraordinary endemic biodiversity, coupled with a high-amplitude record of palaeoenvironmental change, makes it an ideal system to study drivers of past and current biodiversity crises. By linking Pontocaspian palaeoenvironmental and biodiversity changes we will reconstruct biological resilience to environmental change and apply this knowledge to the current Pontocaspian biodiversity crisis to model future diversity shifts under different Global Change scenarios. PRIDE will provide outstanding interdisciplinary technical training, new skills acquisition and career development for 15 early stage researchers. An innovative outreach plan will deliver our results to stakeholders and the public. PRIDE results from existing, successful collaborative relationships and will expand to include 17 first-class private and academic geological and biological institutions allowing Europe to remain world-leading in integrated studies of biodiversity change.", "To": ["2019-02-28, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Netherlands"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-03-01"], "Project_ID": ["642973"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["UNIVERSITY OF LEEDS", "UNIVERSITY OF HULL", "Pannon Egyetem", "THE UNIVERSITY OF SHEFFIELD"], "EU_Contribution": ["EUR 405 000"], "Project_Title": ["Development of flexible pyrolysis-catalysis processing of waste plastics for selective production of high value products through research and innovation"], "Total_Cost": ["EUR 634 500"], "Country": ["United Kingdom", "United Kingdom", "Hungary", "United Kingdom"], "Project_ACR": ["FLEXI-PYROCAT"], "Technology_Description": "The Research and Innovation Staff Exchange project aims to develop and maintain long term collaborations between Universities in the European Union with China and Australia. The collaboration is centered around the goal of advancing beyond the current state-of-the-art of wastes pyrolysis through staff exchanges with world-leading researchers in pyrolysis process engineering, catalysis and modelling/simulation. Advancement beyond the state-of-the-art is the innovation of introducing novel catalysts into the pyrolysis process to produce the next generation of advanced thermal treatment technologies for plastic wastes. ", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-01-01"], "Project_ID": ["643322"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["STICHTING DELTARES", "AALTO-KORKEAKOULUSAATIO", "CENTRO DE ESTUDIOS Y EXPERIMENTACION DE OBRAS PUBLICAS - CEDEX", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "DHI", "INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU GEOLOGIE SI GEOECOLOGIE MARINA-GEOECOMAR", "HR WALLINGFORD LIMITED", "HAMBURGISCHE SCHIFFBAU-VERSUCHSANSTALT GMBH", "INTERNATIONAL ASSOCIATION OF HYDRAULIC ENGINEERING AND RESEARCH", "INSTYTUT BUDOWNICTWA WODNEGO POLSKIEJ AKADEMII NAUK", "INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER", "LOUGHBOROUGH UNIVERSITY", "LABORATORIO NACIONAL DE ENGENHARIA CIVIL", "GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER", "NATURAL ENVIRONMENT RESEARCH COUNCIL", "NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU", "SAMUI DESIGN AND MANAGEMENT LIMITED", "THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN", "UNIVERSITA DEGLI STUDI DI CATANIA", "UNIVERSIDAD DE CANTABRIA", "UNIVERSITY OF HULL", "UNIVERSITAT POLITECNICA DE CATALUNYA", "UNIVERSIDADE DO PORTO", "UNIVERSITEIT TWENTE"], "EU_Contribution": ["EUR 9 979 376,17"], "Project_Title": ["HYDRALAB+ Adapting to climate change"], "Total_Cost": ["EUR 9 979 376,17"], "Country": ["Netherlands", "Finland", "Spain", "France", "Denmark", "Romania", "United Kingdom", "Germany", "Netherlands", "Poland", "France", "United Kingdom", "Portugal", "Germany", "United Kingdom", "Norway", "United Kingdom", "United Kingdom", "Italy", "Spain", "United Kingdom", "Spain", "Portugal", "Netherlands"], "Project_ACR": ["HYDRALAB-PLUS"], "Technology_Description": "HYDRALAB is an advanced network of environmental hydraulic institutes in Europe, which has been effective in providing access to a suite of major and unique environmental hydraulic facilities from across the whole European scientific community.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["INFRAIA-1-2014-2015 - Integrating and opening existing national and regional research infrastructures of European interest"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Netherlands"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Other", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["654110"], "Call_for_Proposal": ["H2020-INFRAIA-2014-2015"]}, -{"Partners": ["HELSINGIN YLIOPISTO", "EURO-ARGO ERIC", "EISCAT SCIENTIFIC ASSOCIATION", "CONSIGLIO NAZIONALE DELLE RICERCHE", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER", "FORSCHUNGSZENTRUM JULICH GMBH", "ISTITUTO NAZIONALE DI GEOFISICA E VULCANOLOGIA", "NATURAL ENVIRONMENT RESEARCH COUNCIL", "Euro-Mediterranean Seismological Centre", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "UNIVERSITAET BREMEN", "UNIVERSITEIT VAN AMSTERDAM", "UNIVERSITA DEL SALENTO", "INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE", "UMWELTBUNDESAMT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (UBA GMBH)", "GOETEBORGS UNIVERSITET", "MARINE BIOLOGICAL ASSOCIATION OF THE UNITED KINGDOM", "THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS", "DEUTSCHES KLIMARECHENZENTRUM GMBH", "NORGES FORSKNINGSRAD", "EUROPEAN MOLECULAR BIOLOGY LABORATORY", "UNIVERSITETET I TROMSOE", "EUROGOOS", "CONSORCIO PARA EL DISENO, CONSTRUCCION, EQUIPAMIENTO Y EXPLOTACION DE LA PLATAFORMA OCEANICA DE CANARIAS", "KOBENHAVNS UNIVERSITET", "ILMATIETEEN LAITOS", "LUNDS UNIVERSITET", "UNIVERSITA DEGLI STUDI DELLA TUSCIA", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "HELMHOLTZ ZENTRUM FUR OZEANFORSCHUNG KIEL", "NORSK INSTITUTT FOR LUFTFORSKNING STIFTELSE", "CARDIFF UNIVERSITY", "THE UNIVERSITY OF EDINBURGH", "CSC-TIETEEN TIETOTEKNIIKAN KESKUS OY", "CINECA CONSORZIO INTERUNIVERSITARIO", "STICHTING EGI"], "EU_Contribution": ["EUR 14 683 534,25"], "Project_Title": ["Environmental Research Infrastructures Providing Shared Solutions for Science and Society"], "Total_Cost": ["EUR 14 998 034,25"], "Country": ["Finland", "France", "Sweden", "Italy", "France", "France", "Germany", "Italy", "United Kingdom", "France", "Switzerland", "Germany", "Netherlands", "Italy", "France", "Austria", "Sweden", "United Kingdom", "United Kingdom", "Germany", "Norway", "Germany", "Norway", "Belgium", "Spain", "Denmark", "Finland", "Sweden", "Italy", "France", "Germany", "Norway", "United Kingdom", "United Kingdom", "Finland", "Italy", "Netherlands"], "Project_ACR": ["ENVRI PLUS"], "Technology_Description": "ENVRIPLUS is a cluster of research infrastructures (RIs) for Environmental and Earth System sciences, built around ESFRI roadmap and associating leading e-infrastructures and Integrating Activities together with technical specialist partners. ENVRIPLUS is driven by 3 overarching goals: 1) favoring cross-fertilization between infrastructures, 2) implementing innovative concepts and devices across RIs, and 3) facilitating research and innovation in the field of environment to an increasing number of users outside the RIs. ENVRIPLUS organizes its activities along a main strategic plan where sharing multi-disciplinary expertise will be most effective. It aims to improve Earth observation monitoring systems and strategies, including actions towards harmonization and innovation, to generate common solutions to many shared information technology and data related challenges, to harmonize policies for access and provide strategies for knowledge transfer amongst RIs. ENVRIPLUS develops guidelines to enhance trans-disciplinary use of data and data-products supported by applied use-cases involving RIs from different domains. ENVRIPLUS coordinates actions to improve communication and cooperation, addressing Environmental RIs at all levels, from management to end-users, implementing RI-staff exchange programs, generating material for RI personnel, and proposing common strategic developments and actions for enhancing services to users and evaluating the socio-economic impacts. ENVRIPLUS is expected to facilitate structuration and improve quality of services offered both within single RIs and at pan-RI level. It promotes efficient and multi-disciplinary research offering new opportunities to users, new tools to RI managers and new communication strategies for environmental RI communities. The produced solutions, services and other project results are made available to all environmental RI initiatives, thus contributing to the development of a consistent European RI ecosystem.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["INFRADEV-4-2014-2015 - Implementation and operation of cross-cutting services and solutions for clusters of ESFRI and other relevant research infrastructure initiatives"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Other", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Other", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other", "Research Organisations", "Other"], "From": ["2015-05-01"], "Project_ID": ["654182"], "Call_for_Proposal": ["H2020-INFRADEV-1-2014-1"]}, -{"Partners": ["PSIQUADRO SOCIETA COOPERATIVA", "ISTITUTO NAZIONALE DI FISICA NUCLEARE", "UNIVERSITA DEGLI STUDI DI PERUGIA", "OBSERVA", "UNIVERSITA POLITECNICA DELLE MARCHE"], "EU_Contribution": ["EUR 249 050"], "Project_Title": ["SHAring Researchers\u2019 Passion for Excellence and Results. European Reserarchers' Night in the Centre of Italy 2014 - 2015"], "Total_Cost": ["EUR 332 065"], "Country": ["Italy", "Italy", "Italy", "Italy", "Italy"], "Project_ACR": ["SHARPER"], "Technology_Description": "The SHARPER project (Sharing Researchers\u2019 Passion for Excellence and Results - The European Researchers\u2019 Night in the Centre of Italy, 2014 \u2013 2015) wants to make the researchers\u2019 quest for excellence accessible to everybody in cities and communities where researchers act and live. ", "To": ["2015-12-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-NIGHT-2014 - European Researchers' Night (NIGHT)"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Italy"], "Activity": ["Other", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2014-05-01"], "Project_ID": ["633367"], "Call_for_Proposal": ["H2020-MSCA-NIGHT-2014"]}, -{"Partners": ["WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER", "UNIVERSITA DELLA CALABRIA", "UNIVERSITA DEGLI STUDI DI CATANIA", "THE GLASGOW CALEDONIAN UNIVERSITY", "UNIWERSYTET WARSZAWSKI", "FONDATION NATIONALE DES SCIENCES POLITIQUES", "SYDDANSK UNIVERSITET", "WIRTSCHAFTSUNIVERSITAT WIEN", "THE COLLEGE OF MANAGEMENT ACADEMIC STUDIES", "UNIVERSIDAD DE SEVILLA", "IMPACT HUB BERLIN GMBH", "THE HUB SICILIA SOCIETA COOPERATIVA", "MUJERES SUPERVIVIENTES DE VIOLENCIAS DE GENERO: DESDE EL SUR CONSTRUYENDO LA IGUALDAD", "MALMO FOTBOLLFORENING", "LES ATELIERS DE ENTREPRENEURIAT HUMANISTE", "FUNDACJA FEMINOTEKA", "social - design - business Verein zur F\u00f6rderung der Kreativ- und Sozialwisrtschaft, gabarage upcycling design", "MINGA 1212 SOCIAL ENTERPRISE ARENA", "INVERCLYDE COMMUNITY DEVELOPMENT TRUST", "FAIVELOVITZ RONNY ADINA", "COOMPANION KOOPERATIV UTVECKLING SKANE EK. FOR."], "EU_Contribution": ["EUR 1 192 500"], "Project_Title": ["For a Better Tomorrow: Social Enterprises on the Move"], "Total_Cost": ["EUR 1 192 500"], "Country": ["Germany", "Italy", "Italy", "United Kingdom", "Poland", "France", "Denmark", "Austria", "Israel", "Spain", "Germany", "Italy", "Spain", "Sweden", "France", "Poland", "Austria", "Israel", "United Kingdom", "Israel", "Sweden"], "Project_ACR": ["FAB-MOVE"], "Technology_Description": "The project \u201cFor a Better Tomorrow: Social Enterprises on the Move (FAB-MOVE)\u201d brings together researchers and practitioners in order to explore the question of how social enterprises can grow and flourish. These objectives will be achieved through a carefully crafted network of academic and non-academic partner organisations co-operating worldwide.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Other", "Other", "Other", "Other", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-01-01"], "Project_ID": ["688991"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT", "UNIVERSITE DE LORRAINE", "UNIVERSITA DEGLI STUDI DI PADOVA", "AALBORG UNIVERSITET", "NOVITOM SAS", "AARHUS UNIVERSITET", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSITE GRENOBLE ALPES", "THE UNIVERSITY OF AUCKLAND", "THE NEW ZEALAND INSTITUTE FOR PLANT AND FOOD RESEARCH LIMITED", "UNIVERSIDAD NACIONAL AUTONOMA DE MEXICO", "SAITAMA UNIVERSITY", "NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY"], "EU_Contribution": ["EUR 175 500"], "Project_Title": ["PROviding new insighT into INteractions between soil fUnctions and Structure"], "Total_Cost": ["EUR 459 000"], "Country": ["France", "France", "Italy", "Denmark", "France", "Denmark", "France", "France", "New Zealand", "New Zealand", "Mexico", "Japan", "Japan"], "Project_ACR": ["PROTINUS"], "Technology_Description": "The PROTINUS proposal assembles a multi-disciplinary team to combine advanced, applied and theoretical research to create a new standard in imaging, analysing, modelling and predicting the interactions between soil structure and soil functions. Soil structure impacts a whole range of services soil renders to ecosystems, including for example contaminant filtering, carbon storage, root growth, and microbiological diversity. ", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-01-01"], "Project_ID": ["645717"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["\"NATIONAL CENTER FOR SCIENTIFIC RESEARCH \"\"DEMOKRITOS\"\"\"", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "UNIVERSITE DE MONS", "BONUS THERAPEUTIC LTD", "BIOIMAG SOLUCIONES DE CONTRASTE SL", "TEXNOLOGIKES LYSEIS BIOEKPOMPIS OE"], "EU_Contribution": ["EUR 472 500"], "Project_Title": ["Multimodal imaging of the in vivo fate of bone transplants"], "Total_Cost": ["EUR 472 500"], "Country": ["Greece", "Spain", "Belgium", "Israel", "Spain", "Greece"], "Project_ACR": ["VIVOIMAG"], "Technology_Description": "The main objective of VIVOIMAG is to develop bone implants including a new contrast agent sensitive to enzymatic activity of metaloproteases, which will permit for the first time to follow the integration and cell differentiation activity in bone tissue bioreactors in vitro and in grafts in vivo using existing non invasive magnetic resonance imaging techniques. The proposal aims at integrating a magnetically functionalized extracellular matrix material into the bone scaffolds, seeding them with cells, implanting them in animal models and following the fate of the implants in vivo using MRI. The aim is to obtain similar results with the magnetically modified scaffolds as the ones obtained currently but having now endowed the grafts with enzymatic reporting activity that can be monitored noninvasively in the living animal. There are currently no methods to detect in situ and in vivo this enzymatic activity without previously sacrificing the transplanted animals, therefore the successful accomplishment of this project would have huge and prolonged impact in the medical field of tissue regeneration.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Greece"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-06-01"], "Project_ID": ["645757"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["UNIVERSITAET HAMBURG", "BIOSYNTIA APS", "CHALMERS TEKNISKA HOEGSKOLA AB", "CHR. HANSEN A/S", "DSM FOOD SPECIALTIES BV", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "STICHTING VU", "TECHNISCHE UNIVERSITAET BERLIN", "THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN", "THE UNIVERSITY OF EDINBURGH", "RIJKSUNIVERSITEIT GRONINGEN", "UNIVERSITY OF YORK"], "EU_Contribution": ["EUR 3 987 358,20"], "Project_Title": ["Synthetic Circuits for Robust Orthogonal Production"], "Total_Cost": ["EUR 3 987 358,20"], "Country": ["Germany", "Denmark", "Sweden", "Denmark", "Netherlands", "Switzerland", "Netherlands", "Germany", "United Kingdom", "United Kingdom", "Netherlands", "United Kingdom"], "Project_ACR": ["SynCrop"], "Technology_Description": "The repertoire of industrially produced fine chemicals in various biological systems will rapidly expand using the tools from the emerging field of synthetic biology. However, the high-level production of non-natural products or de novo activities through synthetic circuits compromises the integrity of host organisms, which significantly impacts or even prevents the development of an industrial pipeline. Our ability to exploit the potential of synthetic biology for industrial production is constrained by our understanding of the integrated cell response when introducing a new synthetic circuit into the homeostatic network of the cell. SynCrop\u2019s main goal is to establish a European Training Network that merges the fragmented scientific expertise in theoretical, experimental and application-driven quantitative biology to educate the next generation of researchers to construct modular and tunable synthetic circuits and foster the development of novel production platforms for food additives (e.g. vitamins, carotenoids and exopolysaccharides). Researchers with inter-disciplinary skills in both experimental and computational biology are needed to solve complex application-driven problems. SynCrop brings together ten academic partners from quantitative biology, cell engineering, microbial physiology and mathematical modelling fields and six industrial partners, including key experts in metabolic engineering and industrial biotechnology. The consortium will provide 15 early-stage researchers with cutting-edge multi-disciplinary research training, through tailored research projects, rigorous exchange of expertise among researchers and partners, and participation in specialised courses, workshops and conferences augmented by extensive training in complementary skills. SynCrop will generate a strong cohort of highly-employable scientists with unique inter-disciplinary and intersectoral skills to address complex questions and develop innovative biotechnological processes.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["764591"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["FONDATION DE L'INSTITUT DE RECHERCHE IDIAP", "PHILIPS ELECTRONICS NEDERLAND B.V.", "UNIVERSITE PAUL SABATIER TOULOUSE III", "UNIVERSITAIR ZIEKENHUIS ANTWERPEN", "FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG", "STICHTING KATHOLIEKE UNIVERSITEIT", "INESC ID - INSTITUTO DE ENGENHARIADE SISTEMAS E COMPUTADORES, INVESTIGACAO E DESENVOLVIMENTO EM LISBOA", "LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN", "INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM", "STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS", "UNIVERSITAET AUGSBURG", "THE UNIVERSITY OF SHEFFIELD"], "EU_Contribution": ["EUR 3 856 029,12"], "Project_Title": ["Training Network on Automatic Processing of PAthological Speech"], "Total_Cost": ["EUR 3 856 029,12"], "Country": ["Switzerland", "Netherlands", "France", "Belgium", "Germany", "Netherlands", "Portugal", "Germany", "Belgium", "Netherlands", "Germany", "United Kingdom"], "Project_ACR": ["TAPAS"], "Technology_Description": "There are an increasing number of people across Europe with debilitating speech pathologies (e.g., due to stroke, Parkinson's, etc). These groups face communication problems that can lead to social exclusion. They are now being further marginalised by a new wave of speech technology that is increasingly woven into everyday life but which is not robust to atypical speech. TAPAS is proposing a programme of pathological speech research, that aims to transform the well-being of these people.", "To": ["2021-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Switzerland"], "Activity": ["Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["766287"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["THE UNIVERSITY OF SHEFFIELD", "TTY-SAATIO", "ASOCIACION CENTRO TECNOLOGICO CEIT-IK4", "UNIVERSITY OF BEDFORDSHIRE", "INNOLAS LASER GMBH"], "EU_Contribution": ["EUR 3 208 740"], "Project_Title": ["Nanoscale self-assembled epitaxial nucleation controlled by interference lithography"], "Total_Cost": ["EUR 3 208 740"], "Country": ["United Kingdom", "Finland", "Spain", "United Kingdom", "Germany"], "Project_ACR": ["NanoStencil"], "Technology_Description": "By overcoming all the limitations of conventional top-down nanostructuring, the NanoStencil project seeks to initiate a new process paradigm for the production of dense arrays of identical nanostructures of precise size, shape and composition. It achieves this by combining the simplicity of structuring with light, with the advantages of molecular self-assembly, to provide a single step, cost effective and state of the art capability for next-generation ordered arrays of nanostructures. New methods to achieve such structures are a vital requirement for the exploitation of devices in the quantum regime. In our approach, laser interference patterning is applied by means of ultrashort pulses to material surfaces at the nanostructure formation phase, where it acts to modify local reaction processes providing energetically favourable sites for the nucleation of self-assembly. The approach is based on some established principles and prior art gained within the consortium, but is yet to be demonstrated at the device scale.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-01-2016-2017 - FET-Open research and innovation actions"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-10-01"], "Project_ID": ["767285"], "Call_for_Proposal": ["H2020-FETOPEN-1-2016-2017"]}, -{"Partners": ["UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSITA DEGLI STUDI DI PALERMO", "UNIVERSIDAD DE SALAMANCA", "UNIVERSITAET HAMBURG", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "UNIVERSITY OF ESSEX", "UNIVERSITEIT UTRECHT", "FONDATION NATIONALE DES SCIENCES POLITIQUES", "NATURAL ENVIRONMENT RESEARCH COUNCIL", "ISTITUTO NAZIONALE DI OCEANOGRAFIA E DI GEOFISICA SPERIMENTALE", "Ministry of National Infrastructure, Energy and Water Resources"], "EU_Contribution": ["EUR 3 893 087,88"], "Project_Title": ["Understanding the Mediterranean Salinity Crisis"], "Total_Cost": ["EUR 3 893 087,88"], "Country": ["France", "France", "Italy", "Spain", "Germany", "Spain", "United Kingdom", "Netherlands", "France", "United Kingdom", "Italy", "Israel"], "Project_ACR": ["SALTGIANT"], "Technology_Description": "As society moves into an era where environmental change has an ever-growing place in the political agenda, the demand for a new generation of scientists working at the interface between the natural and social sciences is growing. SALTGIANT contributes to satisfy this demand within a rare cross-disciplinary network of natural and social scientists dedicated to understanding the formation of the Mediterranean Salt Giant, one of the largest salt deposits on Earth, and its implications for sub-seafloor microbial life, risk assessment in the oil industry, geo-economics of the Mediterranean region and the history of oceanography. SALTGIANT will bring together 22 academic organizations (11 beneficiaries, 11 partners), 2 private sector Oil&Gas companies and 1 specialist in transferable skills training from 8 European countries to stimulate interdisciplinary and intersectorial knowledge exchange between geologists, geophysicists, geochemists, microbiologist, geographers and historians in a network with PhD students at its core. SALTGIANT combines (i) geological and geochemical field work, (ii) laboratory measurements and experiments, (iii) numerical modeling at a wide range of spatial and temporal scales and (iv) empirical social sciences data collection and analysis, guaranteeing exposure of the research fellows to state-of-the-art scientific knowledge and hands-on practical training in a field rich in applications of both intellectual and societal relevance.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2018-01-01"], "Project_ID": ["765256"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["POLITECNICO DI MILANO", "UNIVERSITA DEGLI STUDI DI MILANO", "LUNDS UNIVERSITET", "UNIVERSIDAD DE ZARAGOZA", "UNIVERSITAT POLITECNICA DE VALENCIA", "KARLSRUHER INSTITUT FUER TECHNOLOGIE", "MEDTRONIC BAKKEN RESEARCH CENTER B.V.", "MORTARA INSTRUMENT EUROPE SRL"], "EU_Contribution": ["EUR 3 056 990,04"], "Project_Title": ["MultidisciplinarY training network for ATrial fibRillation monItoring, treAtment and progression"], "Total_Cost": ["EUR 3 056 990,04"], "Country": ["Italy", "Italy", "Sweden", "Spain", "Spain", "Germany", "Netherlands", "Italy"], "Project_ACR": ["MY-ATRIA"], "Technology_Description": "MY-ATRIA brings together universities, companies and hospitals from 5 European countries (Italy, Spain, Sweden, Netherlands and Germany). The main scope of MY-ATRIA is to establish a multidisciplinary network able to develop research and training \u201cwithout walls\u201d among academic, industrial and clinical entities in the area of cardiac, atrial disease. The composite nature of the MY_ATRIA network will ensure a highly qualified training and research infrastructure, which meets the needs of academic research, industrial exploitation and clinical end-users. MY_ATRIA will generate a new profile of Researcher with an intersectoral expertise able to fill the existing gap between basic research and clinical/businessoriented solutions. The training and research activities of MY-ATRIA are designed to pursue innovation in three domains: i) Educational concepts: MY_ATRIA will implement a new, intersectoral paradigm of PhD training to shape a modern professional Researcher with cross-competencies and able to accelerate the transfer of advances in basic science to market and clinics. ii) Basic science: MY_ATRIA will gain new knowledge about atrial functioning, atrial arrhythmias development and response to treatment, using multi-sectoral, model based integrative approach to explore the complex processes of electrical, contractile, and structural remodeling of the atrial myocardium. iii) Technology solutions: MY_ATRIA will develop new methodologies and technologies for the early detection of atrial arrhythmias, its monitoring, progression and risk stratification as well as for a better patient treatment.", "To": ["2021-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-11-01"], "Project_ID": ["766082"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["ALBUFERA ENERGY STORAGE SL", "UNIVERSITY OF LEICESTER", "SCIONIX LIMITED", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "TECHNISCHE UNIVERSITAET GRAZ", "UNIVERSITY OF SOUTHAMPTON", "DANMARKS TEKNISKE UNIVERSITET"], "EU_Contribution": ["EUR 2 998 130"], "Project_Title": ["Sulfur-Aluminium Battery with Advanced Polymeric Gel Electrolytes"], "Total_Cost": ["EUR 2 998 130"], "Country": ["Spain", "United Kingdom", "United Kingdom", "Spain", "Austria", "United Kingdom", "Denmark"], "Project_ACR": ["SALBAGE"], "Technology_Description": "Sulfur-Aluminium Battery with Advanced Polymeric Gel Electrolytes (SALBAGE)", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-01-2016-2017 - FET-Open research and innovation actions"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Spain"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["766581"], "Call_for_Proposal": ["H2020-FETOPEN-1-2016-2017"]}, -{"Partners": ["POLITECNICO DI MILANO", "UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA", "UNIVERSITY OF GLASGOW", "PHILIPPS UNIVERSITAET MARBURG", "TECHNISCHE UNIVERSITAET DRESDEN", "MICRO PHOTON DEVICES S.R.L."], "EU_Contribution": ["EUR 3 106 381"], "Project_Title": ["micro-crystals Single Photon InfraREd detectors"], "Total_Cost": ["EUR 3 106 381,25"], "Country": ["Italy", "Italy", "United Kingdom", "Germany", "Germany", "Italy"], "Project_ACR": ["microSPIRE"], "Technology_Description": "\u00b5SPIRE aims at establishing a technological platform for homo- and hetero- structure based photonic and electronic devices using the self-assembling of epitaxial crystals on patterned Si substrates.", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-01-2016-2017 - FET-Open research and innovation actions"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-11-01"], "Project_ID": ["766955"], "Call_for_Proposal": ["H2020-FETOPEN-1-2016-2017"]}, -{"Partners": ["AARHUS UNIVERSITET", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "VIB", "UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK", "BIOMODICS APS", "HUMBOLDT-UNIVERSITAET ZU BERLIN", "SPINVERSE OY", "Universidade Federal do Par\u00e1"], "EU_Contribution": ["EUR 3 787 932,50"], "Project_Title": ["in vivo optogeneticS, elecTrophysiology and phArmacology with an ultRasonically-powered DUST for Parkinson's Disease"], "Total_Cost": ["EUR 3 803 057,50"], "Country": ["Denmark", "Germany", "France", "Belgium", "Ireland", "Denmark", "Germany", "Finland", "Brazil"], "Project_ACR": ["STARDUST"], "Technology_Description": "The main goal of the STARDUST project is to realize a novel wireless implantable and independent micro-scale device (200x200x200 \u00b5m3) enabling in-vivo electrophysiology, optogenetics and ultra-localized drug delivery in freely moving animals. The device will be used to target specific neural circuits of the brain and test a new therapeutic approach for Parkinson\u2019s Disease (PD). ", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-01-2016-2017 - FET-Open research and innovation actions"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["767092"], "Call_for_Proposal": ["H2020-FETOPEN-1-2016-2017"]}, -{"Partners": ["Fundaci\u00f3 Institut d'Investigaci\u00f3 Biom\u00e8dica de Bellvitge", "Academisch Medisch Centrum bij de Universiteit van Amsterdam", "ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS", "INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE", "VIB", "TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY", "MEDIZINISCHE UNIVERSITAET WIEN", "IBM ISRAEL - SCIENCE AND TECHNOLOGY LTD", "APPLIED RESEARCH USING OMIC SCIENCES SL", "EVOTEC (FRANCE) SAS"], "EU_Contribution": ["EUR 3 831 957,72"], "Project_Title": ["Targeting the metabolism-immune system connections in Cancer"], "Total_Cost": ["EUR 3 831 957,72"], "Country": ["Spain", "Netherlands", "France", "France", "Belgium", "Israel", "Austria", "Israel", "Spain", "France"], "Project_ACR": ["META-CAN"], "Technology_Description": "\"Cancer cells show common features of profound metabolic changes and escape from the immune system, independently of their tissue of origin. These metabolic adaptations are not limited to glucose metabolism (the \"\"Warburg effect\"\") but are more general and affect several metabolic pathways in cancer cells as well as in the stroma, including immune cells. This network will explore how nutrients and hypoxia regulate the tumor-immune system interplay, and how this communication is controlled by oncogenes, metabolic regulators and current or potential drugs targeting metabolism. ", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-09-01"], "Project_ID": ["766214"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["DANMARKS TEKNISKE UNIVERSITET", "BANG & OLUFSEN AS", "FORCE TECHNOLOGY", "UNIVERSITE DE NANTES", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "DXO LABS", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "BANGOR UNIVERSITY", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V."], "EU_Contribution": ["EUR 4 076 702,28"], "Project_Title": ["Hyperrealistic Imaging Experience"], "Total_Cost": ["EUR 4 076 702,28"], "Country": ["Denmark", "Denmark", "Denmark", "France", "France", "France", "United Kingdom", "United Kingdom", "United Kingdom", "Germany", "Germany"], "Project_ACR": ["RealVision"], "Technology_Description": "The aim of realistic digital imaging is the creation of high quality imagery, which faithfully represents the physical environment. The ultimate goal is to create images, which are perceptually indistinguishable from a real scene. The RealVision network brings together leading universities, centers focused on industrial development and companies in Multimedia, Optics, Visual Communication, Visual Computing, Computer Graphics and Human Vision research across Europe, with the aim of training a new generation of scientists, technologists, and entrepreneurs that will move Europe into a leading role in innovative hyper-realistic imaging technologies. Current imaging technologies capture only a fraction of visual information that the human eye can see. The colours and dynamic range are inadequate for most real-world scenes and not all depth cues required for natural 3D vision are captured. This limits the realism of the experience and has hampered the introduction of 3D technology. Advancement in imaging technologies makes it possible to circumvent these bottlenecks in visual systems. As a result, new visual signal-processing areas have emerged such as light fields, ultra-high definition, highframe rate and high dynamic range imaging. The novel combinations of those technologies can facilitate a hyper-realistic visual experience. This will without doubt be the future frontier for new imaging systems. However there are several technological barriers that need to be overcome as well as challenges in what are the best solutions perceptually. The goal of this network is to combine expertise from several disciplines as engineering, computer science, physics, vision science and psychology \u2013 usually disconnected \u2013 and train ESRs to be capable of working with all stages and aspects of visual processing to overcome existing interdisciplinary and intersectorial barriers to efficiently develop truly perceptually better visual imaging systems.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["765911"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM", "UNIVERSITY OF LEICESTER", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSIDAD COMPLUTENSE DE MADRID", "UNIVERSITEIT VAN AMSTERDAM", "WAGENINGEN UNIVERSITY", "KARLSRUHER INSTITUT FUER TECHNOLOGIE", "LEIBNIZ - INSTITUT FUER PFLANZENGENETIK UND KULTURPFLANZENFORSCHUNG", "UNIVERSITAET HAMBURG", "UNIVERSITAT WIEN"], "EU_Contribution": ["EUR 3 107 819,88"], "Project_Title": ["Meiotic Control of Recombination in Crops"], "Total_Cost": ["EUR 3 107 819,88"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom", "France", "France", "Spain", "Netherlands", "Netherlands", "Germany", "Germany", "Germany", "Austria"], "Project_ACR": ["MEICOM"], "Technology_Description": "The increasing growth of human population and the intrinsic increase in world pollution, together with the uncertain challenge of climate change will undeniably require an internationally sustained effort to meet the global food demand. An increase of food production by at least 50% has been projected to be necessary by 2050. Thus, Food Security is one of the most important challenges for the future. Classical plant breeding has been crucial to improve our crop species from the beginning of human civilizations until now. Classical plant breeding harnesses the natural genetic variation that is generated by meiotic recombination. During meiosis, new allele combinations are obtained which could confer new improved phenotypes. Nevertheless, plant breeders are reaching the limits of this methodology. These boundaries are intrinsically shaped by the restrictions on the frequency and distribution of meiotic recombination in the different crop species. In cereals, it has been estimated that 30-50% of genes rarely (if at all) recombine, limiting the genetic variation available to use by plant breeders. The MEICOM consortium has been designed to prepare future scientists, academics, plant breeders and policy makers in how to manipulate and control meiotic recombination in different crops (brassicas, wheats, barley, tomato, maize) and to provide a sustainable assurance on Food Security for the future. MEICOM is a network of the finest European Plant Meiosis Researchers with internationally acclaimed industrial partners to gain knowledge and transfer it into our training programme and the general public.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["765212"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["DANMARKS TEKNISKE UNIVERSITET", "KOBENHAVNS UNIVERSITET", "UNIVERSITEIT ANTWERPEN", "ACCENT PRO 2000 s.r.l.", "STICHTING CENTRUM VOOR WISKUNDE EN INFORMATICA", "PAUL SCHERRER INSTITUT", "BUNDESANSTALT FUER MATERIALFORSCHUNG UND -PRUEFUNG", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "LUNDS UNIVERSITET", "THE UNIVERSITY OF MANCHESTER", "OCV CHAMBERY INTERNATIONAL"], "EU_Contribution": ["EUR 3 999 114"], "Project_Title": ["MUltiscale, Multimodal and Multidimensional imaging for EngineeRING"], "Total_Cost": ["EUR 3 999 114"], "Country": ["Denmark", "Denmark", "Belgium", "Romania", "Netherlands", "Switzerland", "Germany", "France", "Sweden", "United Kingdom", "France"], "Project_ACR": ["MUMMERING"], "Technology_Description": "The overarching goal of MUMMERING is to create a research tool that encompasses the wealth of new 3D imaging mo-dalities that are surging forward for applications in materials engineering, and to create a doctoral programme that trains 15 early stage researchers (ESRs) in this tool. This is urgently needed to prevent that massive amounts of valuable tomogra-phy data ends on a virtual scrapheap. The challenge of handling and analysing terabytes of 3D data is already limiting the level of scientific insight that is extracted from many data sets. With faster acquisition times and multidimensional modali-ties, these challenges will soon scale to the petabyte regime. To meet this challenge, we will create an open access, open source platform that transparently and efficiently handles the complete workflow from data acquisition, over reconstruction and segmentation to physical modelling, including temporal models, i.e. 3D \u201cmovies\u201d. We consider it essential to reach this final step without compromising scientific standards if 3D imaging is to become a pervasive research tool in the visions for Industry 4.0.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-01-01"], "Project_ID": ["765604"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI UDINE", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "TECHNISCHE UNIVERSITEIT DELFT", "ISTANBUL TEKNIK UNIVERSITESI", "UNIVERSITAT AUTONOMA DE BARCELONA", "MAGNES AG", "RISE RESEARCH INSTITUTES OF SWEDEN AB", "INSTITUT JOZEF STEFAN", "VRIJE UNIVERSITEIT BRUSSEL", "UNIVERSITATEA POLITEHNICA DIN BUCURESTI", "AKADEMIA GORNICZO-HUTNICZA IM. STANISLAWA STASZICA W KRAKOWIE", "TEKNISKA HOGSKOLAN I JONKOPING AB", "INEB-INSTITUTO NACIONAL DE ENGENHARIA BIOMEDICA", "ELSYCA NV", "LIMACORPORATE SPA"], "EU_Contribution": ["EUR 3 726 379,44"], "Project_Title": ["Advanced integrative solutions to Corrosion problems beyond micro\u2013scale: towards long-termdurability of miniaturized Biomedical, Electronic and Energy systems"], "Total_Cost": ["EUR 3 726 379,44"], "Country": ["Italy", "Switzerland", "Netherlands", "Turkey", "Spain", "Switzerland", "Sweden", "Slovenia", "Belgium", "Romania", "Poland", "Sweden", "Portugal", "Belgium", "Italy"], "Project_ACR": ["mCBEEs"], "Technology_Description": "mCBEEs Innovative Training Network is a joint venture between academy and industry with a primary goal to train young researchers in the field of corrosion and corrosion protection of micro- and nanodevices. The network focuses on the study of corrosion mechanisms beyond microscale of components in miniaturized systems in different environments using localized techniques, and the development of multifunctional protective coatings to increase the long-term durability of such components. Corrosion phenomena occurring in micro- and nanodimensional components can develop in a completely different path than in their bulk counterparts and corrosion might influence the functional properties of small components in a much more severe manner. Three main strategic fields where corrosion could seriously compromise the performance of micro- or nanodevices have been identified: biotechnology (micro/nano-robotic implants, micro/nano-electrodes for recording and stimulating neuronal activity, or micro-featured prosthesis implants); electronics (micro/nano-components in electronic boards, magnetooptical thin films, multiferroic micro/nano-devices); and energy technology (metallic foam-based micro- and nanostructured electrodes, self-standing nanoarchitectures). Several disciplines (physics, electrochemistry, engineering, biology and robotics) converge to provide a multidisciplinary approach to accomplish mCBEEs goals. The ITN brings together 15 beneficiaries and 3 partners including 4 research institutes and 4 private companies belonging to 9 EU Member states, and to 2 associated states (Switzerland, Turkey). The Consortium complementarity will enable a high-level, multifaceted educational programme, where specials efforts will be done to bridge fundamental research with industrial applications. The educational programme is integrated with training in soft skills and aims at providing a network of highly qualified researchers able to tackle challenges both in Academia and Industry.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-10-01"], "Project_ID": ["764977"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["TECHNISCHE UNIVERSITAET DRESDEN", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "UNIVERSITAET GRAZ", "UNIVERSITE DE LIEGE", "THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 3 997 843,75"], "Project_Title": ["Mechanics with Molecules"], "Total_Cost": ["EUR 3 997 843,75"], "Country": ["Germany", "France", "Spain", "Austria", "Belgium", "United Kingdom"], "Project_ACR": ["MEMO"], "Technology_Description": "In this project, single molecule-machines will be constructed and tested on a surface and one at a time, controlling the rotation and the work delivered by a single molecule-motor directly at the atomic scale. The molecule motors and gears, designed and tested by MEMO, will be further adapted to applications requiring collective and synchronous motion. ", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-01-2016-2017 - FET-Open research and innovation actions"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["766864"], "Call_for_Proposal": ["H2020-FETOPEN-1-2016-2017"]}, -{"Partners": ["CONSIGLIO NAZIONALE DELLE RICERCHE", "THE TRUSTEES OF BOSTON UNIVERSITY", "INSTITUT CURIE", "REGION NORDJYLLAND (NORTH DENMARK REGION)", "FLUIGENT SA", "HANSABIOMED LIFE SCIENCES OU"], "EU_Contribution": ["EUR 2 982 275"], "Project_Title": ["Integrated nanoparticle isolation and detection system for complete on-chip analysis of exosomes"], "Total_Cost": ["EUR 2 983 525"], "Country": ["Italy", "United States", "France", "Denmark", "France", "Estonia"], "Project_ACR": ["INDEX"], "Technology_Description": "The aim of Project INDEX is to isolate and characterize nanoparticles available in bodily fluids through development and integration of novel technological breakthroughs. The technology will enable the analysis of clinically valuable nanoparticles called exosomes towards new generation diagnostics. Exosomes are known to mediate communication between cells and their effective utilization holds a great promise of revolutionizing the standard of clinical care. However, their detection and molecular profiling is technically challenging. The proposed technology will isolate exosomes that are as small as 30nm in diameter from human plasma with high purity, and provide in-depth, multi-parameter characterization of the particles through digital counting, size determination, and biological phenotyping. ", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-01-2016-2017 - FET-Open research and innovation actions"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-10-01"], "Project_ID": ["766466"], "Call_for_Proposal": ["H2020-FETOPEN-1-2016-2017"]}, -{"Partners": ["UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK"], "EU_Contribution": ["EUR 187 866"], "Project_Title": ["Exploring gender equality in Irish higher education: Qualitative case-study research into the response to, and process of Athena SWAN"], "Total_Cost": ["EUR 187 866"], "Country": ["Ireland"], "Project_ACR": ["GendeResearchIreland"], "Technology_Description": "It has been shown that gender equality interventions in the higher education sector are vital in addressing career advancement challenges facing female academics and researchers, in particular the higher up the career ladder researchers progress. This proposed research would explore a gender equality intervention, Athena SWAN, which seeks to encourage commitment to advancing the careers of women in science. It has been shown that barriers to career advancement are mainly due to institutional factors, rather than individual ones, such as career drive or skill. Strengthening research and innovation in Europe, with respect to encouraging gender diversity to support science excellence and relevance, is an identified priority of Horizon 2020. This proposed study would explore the response to, and processes of, the Athena SWAN programme in one European country, Ireland. With a number of EC funded projects in Europe, and research growing, the time is ripe for conducting this research and informing the developing theoretical and policy context for gender equality in higher education in Europe. Athena SWAN is a new intervention in Ireland (since 2015) and this novelty in the process, alongside the context of change within institutions, would elicit a wealth of qualitative data findings that would be generalisable across European institutions. Given my expertise in qualitative research methods and participation in a FP7 gender equality project, I am in the best position to restart my career in this field of inquiry, within a highly stimulating and renowned social science research environment. Supporting this original research would result in a wealth of useful findings for peer researchers, the policy sector and the wider research and innovation community in Europe, as well as engaging with the public. I would seek to promote the Fellowship with a zeal reflecting the sentiment of the extraordinary woman in science who inspired this programme, Dr. Marie Sk\u0142odowska-Curie.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["750408"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ASTON UNIVERSITY", "MIMETAS BV", "ST GEORGE'S HOSPITAL MEDICAL SCHOOL", "UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK", "UNIVERSITA DEGLI STUDI DI TORINO", "INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE", "UNIVERSITAET ROSTOCK", "FUNDACION PARA LA INVESTIGACION DEL HOSPITAL UNIVERSITARIO LA FE DE LA COMUNIDAD VALENCIANA", "KATHOLIEKE UNIVERSITEIT LEUVEN", "UNIVERSITEIT MAASTRICHT"], "EU_Contribution": ["EUR 3 929 698,80"], "Project_Title": ["Innovation in modelling Placenta for Maternal and Fetal Health"], "Total_Cost": ["EUR 3 929 698,80"], "Country": ["United Kingdom", "Netherlands", "United Kingdom", "Ireland", "Italy", "France", "Germany", "Spain", "Belgium", "Netherlands"], "Project_ACR": ["iPLACENTA"], "Technology_Description": "\u201cThe placenta is the least understood human organ but arguably one of the most important\u201d-NIH Human Placenta Project . Innovation in Modelling Placenta for Maternal and Fetal Health (iPLACENTA) is a European Training Network (ETN), and will act as a springboard for promoting international, intersectoral and multi/inter-disciplinary training, career development and collaboration of fifteen early-stage researchers (ESRs) in Maternal and Fetal Health. iPLACENTA will improve our ability to study, model and visualise the placenta. iPLACENTA focuses on doctoral-level training and will be delivered by eleven participating universities located in ten different European countries. It coordinates research and training collaboration among world-leading academic institutions in Europe, providing a new combination of in-depth international expertise. iPLACENTA\u2019s unique network aims are to improve our ability to study the placenta through in vitro and mathematical modelling (WP1&2). Whilst enhancing visualisation and assessment of the placenta in animal models and the clinic, thus enhancing investigation and prognosis of complicated pregnancies. To link the research to industrial exploitation, the network brings together four different businesses; two established companies as beneficiaries Mimetas (MIM) (organ-on-a-chip developer) and Moor, a clinical-technology specialist, together with two partners that are industrial global brands Samsung (SAM) and FujifFilm VisualSonics (FUJ). Together they will work with academics and clinicians to develop new placenta-on-a-chip technology (WP1), in silico placenta modelling (WP2), new modalities of laser technology to visualise the placenta in vivo (WP3), improve maternal-cardiovascular assessment and validate novel ultrasound tools for diagnosis of complicated pregnancies (WP3). Cross-sectorial training delivered by Business and Law Schools, Industry, Clinical specialist and European leaders in OpenScience-OpenInnovation.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["765274"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["CHALMERS TEKNISKA HOEGSKOLA AB", "NPL MANAGEMENT LIMITED", "LATVIJAS UNIVERSITATE", "UNIVERSITY OF SURREY", "BEN-GURION UNIVERSITY OF THE NEGEV"], "EU_Contribution": ["EUR 2 991 978,75"], "Project_Title": ["High Frequency Topological Insulator devices for Metrology"], "Total_Cost": ["EUR 2 991 978,75"], "Country": ["Sweden", "United Kingdom", "Latvia", "United Kingdom", "Israel"], "Project_ACR": ["HiTIMe"], "Technology_Description": "In this project we will study and exploit the properties of 3D topological insulator (TI) materials incorporated into high frequency devices. The main driver of the project is the prospect of using a TI nanoribbon to create a topologically protected single-electron charge pump that can be used as a metrological quantum current standard, or in other words to lay the technological foundations for a TI-based device that can realize the SI Ampere. An accurate charge pump that can operate at temperatures and magnetic fields achievable using affordable table-top systems would be of immediate use in the realization of the Ampere. The technological development in this project will lay the groundwork or charge pumping in TI nanoribbons, as well as for other devices that exploit the unique properties of TI for high-frequency applications including sensing, precision measurement and topologically protected quantum computation. ", "To": ["2022-01-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-01-2016-2017 - FET-Open research and innovation actions"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["766714"], "Call_for_Proposal": ["H2020-FETOPEN-1-2016-2017"]}, -{"Partners": ["COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH", "ASG SUPERCONDUCTORS SPA", "BABCOCK NOELL GMBH", "ELYTT ENERGY SL", "OXFORD INSTRUMENTS NANOTECHNOLOGY TOOLS LIMITED", "SIGMAPHI", "TESLA ENGINEERING LIMITED", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "KARLSRUHER INSTITUT FUER TECHNOLOGIE", "PAUL SCHERRER INSTITUT", "SCIENCE AND TECHNOLOGY FACILITIES COUNCIL"], "EU_Contribution": ["EUR 501 097,50"], "Project_Title": ["Future Superconducting Magnet Technology"], "Total_Cost": ["EUR 501 097,50"], "Country": ["France", "Switzerland", "Italy", "Germany", "Spain", "United Kingdom", "France", "United Kingdom", "France", "Germany", "Switzerland", "United Kingdom"], "Project_ACR": ["FuSuMaTech"], "Technology_Description": "The CERN\u2019s projects, HL-LHC and FCC, will create a big push in the state of the art of High-Field Superconducting magnets in the ten coming years. The performance of superconducting materials such as Nb3Sn and HTS will be developed to yield higher performance at lower costs and the construction materials and techniques will be advanced. At the same time, in the context of Energy\u2019s savings, Industry is experiencing a renewed interest in the domain of industrial superconductivity with fault current limiters, wind generators, electric energy storage, etc. Besides, Medical Research shows a strong interest in High-Field MRI, especially for the brain observation. Considering the social impact of the investment of the HL-LHC project and FCC study, CERN and CEA have established a Working Group on Future Superconducting Magnet Technology (FuSuMaTech).The Working Group has explored a large spectrum of possible synergies with Industry, and has proposed a set of relevant R&D&I projects to be conducted between Academia and industry. To keep the leading position of Europe in the domain, the most efficient way is to support joint activities of Industry and academic partners on the common concerns in view of overcoming the technological barriers. The FuSuMaTech Initiative aims to create the frame of collaborations and to provide common tools to all the EU actors of the domain. The FuSuMatech Initiative is a dedicated and large scale silo breaking programme which will create a sustainable European Cluster in applied Superconductivity. It will enlarge the innovative potential especially in High Field NMR and MRI, opening future breakthroughs in the brain observation. The FuSuMaTech Phase 1 is the first step of the FuSuMaTech Initiative. It is based on practical cases studies and will consist in preparing:", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-03-2017 - FET-Open Coordination and Support Actions"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations"], "From": ["2017-11-01"], "Project_ID": ["766974"], "Call_for_Proposal": ["H2020-FETOPEN-3-2017"]}, -{"Partners": ["FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.", "ELESTOR BV", "BAR ILAN UNIVERSITY", "MAGYAR TUDOMANYOS AKADEMIA TERMESZETTUDOMANYI KUTATOKOZPONT", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "JENABATTERIES GMBH", "AMER-SIL SA", "INDUSTRIE DE NORA SPA-IDN", "ZURCHER HOCHSCHULE FUR ANGEWANDTE WISSENSCHAFTEN", "VYSOKA SKOLA CHEMICKO-TECHNOLOGICKA V PRAZE", "UNIVERSITAET STUTTGART"], "EU_Contribution": ["EUR 3 796 578,36"], "Project_Title": ["European Training Network to improve materials for high-performance, low-cost next- generation redox-flow batteries"], "Total_Cost": ["EUR 3 796 578,36"], "Country": ["Germany", "Netherlands", "Israel", "Hungary", "France", "Germany", "Luxembourg", "Italy", "Switzerland", "Czech Republic", "Germany"], "Project_ACR": ["FlowCamp"], "Technology_Description": "Renewable energy sources like wind turbines require large-scale, stationary energy storage systems to balance out fluctuations in energy generation. FlowCamp will advance the development of one of the most promising storage systems: redox-flow batteries (RFBs). The recruited fellows will develop materials (membranes, electrodes, electrolytes, catalysts, sealing materials) and macrohomogeneous models for three next generation RFBs (hydrogen-bromine, organic and zinc-air systems). They will then upscale the new systems to prototype level (TRL4/5), and validate them using the cutting-edge battery testing facilities available for the prestigious German-funded RedoxWind project at Fraunhofer ICT. The new RFB technologies can be combined in energy storage systems tailored to a wide variety of application scenarios, with lower cost, longer service life and higher efficiency than conventional (e.g. Li-ion) storage devices. ", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["765289"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["UNIVERSITY OF SURREY", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA", "TECHNISCHE UNIVERSITAET WIEN", "HEIDELBERGCEMENT AG"], "EU_Contribution": ["EUR 3 415 255,56"], "Project_Title": ["Engineered Calcium-Silicate-Hydrates for Applications"], "Total_Cost": ["EUR 3 415 255,56"], "Country": ["United Kingdom", "Switzerland", "Italy", "Austria", "Germany"], "Project_ACR": ["ERICA"], "Technology_Description": "ERICA stands for engineered calcium-silicate-hydrates for applications. Inorganic hydrates, such as C-S-H, are used in applications from construction to dentistry. In every case, there is need to optimise the hydrate properties for the application. More reactive cements are needed to lower the CO2 impact of construction. Dentistry needs improved mechanical stability. The traditional way to improve hydrates is by trial and error. This is ineffective. ERICA offers a transformative materials science approach based on gaining detailed understanding the associated nanoscience. ERICA seeks coherent understanding and control of hydrate nucleation and growth as a means to control properties; of the first water sorption cycle when hydrates undergo structural change the consequences of which for performance are only just becoming apparent; and of water transport in hydrates that severely impacts degradation. To do this ERICA exploits recent developments in understanding of hydrate chemistry, in 1H NMR relaxometry and in numerical modeling. Success with ERICA will (i) give industry ways to target design hydrates; (ii) create numerical software tools to model hydrate performance; and (iii) leave good practice and know-how to adopt emergent methods. ERICA trains 13 multi-disciplinary researchers: ESRs ready to find employment with cement product manufacturers, instrumentation manufacturers, in numerical modeling and in academia. This cohort is much needed by industry. The ESRs receive comprehensive academic and transferable skills training comprised of residential schools, workshops, peer learning and industry secondments. Training and dissemination are delivered in collaboration with the industry-academic cement science network: NANOCEM. Courses will be made into MOOCs. ERICA is led by 4 universities and an international cement manufacturer. It is supported by 5 Partner companies.", "To": ["2021-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-11-01"], "Project_ID": ["764691"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI ROMA TRE", "UNIVERSITY OF GLASGOW", "IHP GMBH - INNOVATIONS FOR HIGH PERFORMANCE MICROELECTRONICS/LEIBNIZ-INSTITUT FUER INNOVATIVE MIKROELEKTRONIK", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "NEXTNANO GMBH"], "EU_Contribution": ["EUR 3 206 498,75"], "Project_Title": ["Far-infrared Lasers Assembled using Silicon Heterostructures"], "Total_Cost": ["EUR 3 206 498,75"], "Country": ["Italy", "United Kingdom", "Germany", "Switzerland", "Germany"], "Project_ACR": ["FLASH"], "Technology_Description": "The THz part of the electromagnetic spectrum (0.3-10 THz) is currently exploited in commercial security screening systems (weapon detection beneath clothes), medical diagnostics tools (skin and breast cancer, burns, and in ophthalmology) and production-line monitoring (non-destructive test in the pharmaceutical industry). Existing sources of THz radiation are still too large and expensive to be a massively deployed in all of the existing and proposed applications, which include large bandwidth wireless communications and the extension of security screening to far-infrared spectroscopic identification of chemicals and explosives up to 10 THz. A lower production cost, a higher level of integration with control electronics, and a broader range of emitted wavelength are all desirable to expand the application of THz radiation.", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-01-2016-2017 - FET-Open research and innovation actions"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-11-01"], "Project_ID": ["766719"], "Call_for_Proposal": ["H2020-FETOPEN-1-2016-2017"]}, -{"Partners": ["Teknologian tutkimuskeskus VTT Oy", "CARL VON OSSIETZKY UNIVERSITAET OLDENBURG", "UNIVERSITY OF DURHAM", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "IBM RESEARCH GMBH"], "EU_Contribution": ["EUR 2 919 037,50"], "Project_Title": ["Energy Filtering Non-Equilibrium Devices"], "Total_Cost": ["EUR 2 919 037,50"], "Country": ["Finland", "Germany", "United Kingdom", "France", "Switzerland"], "Project_ACR": ["EFINED"], "Technology_Description": "This project aims for revolutionary energy filtering nano-devices for information and communications technology (ICT). It is at the intersection of phononics, photonics, nanoscale electro-thermal devices and molecular engineering. By building new energy filtering devices down to molecular scales we aim to generate new knowledge and understanding of the electronic, phononic and near-field energy/heat fluxes at the fundamental limits of nano-scale energy management, and to demonstrate novel proof-of-concept non-equilibrium phonon engineered electro-thermal devices in real applications. The efficient nano-scale thermal management necessitate developing new theoretical and experimental tools for understanding and mastering the individual non-equilibrium energy/particle channels and inter-channel couplings. Control of the physical mechanisms behind non-equilibrium electronic energy filtering effects will be firstly addressed by non-linear transport in molecular junctions by developing new research tools that combine state-of-the-art molecular synthesis, bolometers, scanning probe microscopy technologies and theoretical modelling. In parallel with the molecular bottom-up approach, we will work with scalable thermionic nano-junctions, which not only have great technological potential of their own but also serve as a model system for the molecular devices. By employing non-linear out of equilibrium electro-thermal effects in molecular and scaled-down junction systems, we pursue the realization of proof-of-concept ICT devices utilizing these technologies within the time span of the project. This project will combine synergies in theory, experiment and technology-development covering different fields from chemistry to electronics. The project partners, who are leaders in their respective fields, form a consortium that is uniquely positioned to achieve the ambitious objectives.", "To": ["2021-06-30, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-01-2016-2017 - FET-Open research and innovation actions"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Finland"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-01-01"], "Project_ID": ["766853"], "Call_for_Proposal": ["H2020-FETOPEN-1-2016-2017"]}, -{"Partners": ["COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "DANMARKS TEKNISKE UNIVERSITET", "QUANTUMWISE A/S", "UNIVERSITE PARIS DIDEROT - PARIS 7", "CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL", "UNIVERSITAT DE VALENCIA"], "EU_Contribution": ["EUR 3 894 248,70"], "Project_Title": ["Concepts and tools in molecular spintronics"], "Total_Cost": ["EUR 3 894 248,70"], "Country": ["France", "Denmark", "Denmark", "France", "Germany", "Spain"], "Project_ACR": ["COSMICS"], "Technology_Description": "Molecular spintronics is an emergent field combining the flexibility of molecular electronics and and molecular magnetism with the advantages of spintronics. Its main goal is the manipulation of the electron spin by a wise combination of ad-hoc molecules and inorganic substrate. Besides the rich magnetic behavior resulting from the interaction between a magnetic molecule and a metal surface, or vice versa, additional functions such as switchability by external parameters (light, voltage) can be integrated. This multi-disciplinary field offers a wide range of routes towards spin-based devices with potential technological applications in information storage and processing However, due to the very large number of possible material combinations there is an urgent need for fundamental understanding, guiding concepts and tools to scale up and systematize the search of new smart functional molecular designs. Our scientific target is to develop a modelling platform around molecular spintronics that is essential to stimulate fundamental as well as applied/technological research and facilitate the emergence of new key enabling technologies.", "To": ["2021-10-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-01-2016-2017 - FET-Open research and innovation actions"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["766726"], "Call_for_Proposal": ["H2020-FETOPEN-1-2016-2017"]}, -{"Partners": ["UNIVERSITAETSKLINIKUM AACHEN", "IDRYMA IATROVIOLOGIKON EREUNON AKADEMIAS ATHINON", "MOSAIQUES DIAGNOSTICS GMBH", "MEDIZINISCHE UNIVERSITAET WIEN", "RD NEPHROLOGIE SAS", "INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE", "UNIVERSITEIT MAASTRICHT", "KAROLINSKA INSTITUTET", "DSM R & D SOLUTIONS BV"], "EU_Contribution": ["EUR 2 795 346"], "Project_Title": ["Combatting the CardioRenal Syndrome: towards an integrative Analysis to reduce cardiovascular burden in chronic kidney disease"], "Total_Cost": ["EUR 2 795 346"], "Country": ["Germany", "Greece", "Germany", "Austria", "France", "France", "Netherlands", "Sweden", "Netherlands"], "Project_ACR": ["CaReSyAn"], "Technology_Description": "Successfully combatting a complex disease requires multi-disciplinary and methodically well-trained scientists. CaReSyAn strives to accomplish exactly this: we will train scientists to successfully integrate proteomics, clinical, experimental and bioinformatical analyses to enhance the understanding, diagnosis and therapy of the cardiorenal syndrome (CRS). CRS comprises disorders of the heart, vessels and kidneys, including the increased development of cardiovascular disease (CVD) in patients with chronic kidney disease (CKD). With ~45% of all deaths in CKD patients caused by CVD, the socio-economic burden of CRS is extremely high.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-01-01"], "Project_ID": ["764474"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["FYZIKALNI USTAV AV CR V.V.I", "THE UNIVERSITY OF NOTTINGHAM", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "CENTRO DE CALCULO IGS SOFTWARE SOCIEDAD LIMITADA", "UNIVERZITA KARLOVA", "JOHANNES GUTENBERG-UNIVERSITAT MAINZ"], "EU_Contribution": ["EUR 3 682 973,75"], "Project_Title": ["Antiferromagntic spintronics"], "Total_Cost": ["EUR 3 682 973,75"], "Country": ["Czech Republic", "United Kingdom", "Germany", "Spain", "Czech Republic", "Germany"], "Project_ACR": ["ASPIN"], "Technology_Description": "The aim of the project is to open and explore a new research avenue, with emerging and future information technologies at its horizon, where antiferromagnets take the center stage. Antiferromagnets and ferromagnets represent two fundamental forms of magnetism with antiferromagnets being the more abundant of the two. However, it has been notoriously difficult to manipulate and detect antiferromagnets by any practical means due to their compensated magnetic moment. This has left antiferromagnets over their hundred-year history virtually unexploited and only poorly explored, in striking contrast to the thousands of years of fascination and utility of ferromagnets. The project builds on our very recent discovery of a new relativistic spin-torque phenomenon that allow us to efficiently control antiferromagnetic moments in spintronic devices and by this to unlock a multitude of known and newly identified unique features of this \u201cdormant-giant\u201d class of materials. We propose to explore three intertwined research areas in order to scientifically establish: (i) The concept of antiferromagnetic memory-logic suitable for the development of future \u201cBeyond Moore\u201d information technologies. (ii) The concept of antiferromagnetic memory-logic components responding to pulses of lengths downscaled by twelve orders of magnitude from seconds to picoseconds. (iii) The concept in which antiferromagnets provide a unifying platform for realizing synergies among three prominent fields of contemporary condensed matter physics, namely spintronics, Dirac quasiparticles, and topological phases. Our very recent achievements, including the demonstration of a USB proof-of-concept antiferromagnetic memory, make Europe a birthplace of the emerging field of antiferromagnetic spintronics. To contribute in a decisive way that the future science and technology impact of the field remains in Europe, we bring together a critical mass of seven academic and a SME partner covering all the necessary skills.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-01-2016-2017 - FET-Open research and innovation actions"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Czech Republic"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["766566"], "Call_for_Proposal": ["H2020-FETOPEN-1-2016-2017"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM", "UNIVERSITEIT LEIDEN", "Honda Research Institute Europe GmbH", "NEC EUROPE LTD"], "EU_Contribution": ["EUR 2 060 348,04"], "Project_Title": ["Experience-based Computation: Learning to Optimise"], "Total_Cost": ["EUR 2 060 348,04"], "Country": ["United Kingdom", "Netherlands", "Germany", "United Kingdom"], "Project_ACR": ["ECOLE"], "Technology_Description": "The overall theme of our proposed doctoral programme is ECOLE: Experience-based COmputation: Learning to optimisE. It seeks novel synergies between nature inspired optimisation and machine learning to address new challenges that arise in industry due to the increasing complexity of products, product development and production processes. The unique aspect of ECOLE is to study and capture the notion of experience that is associated with expert engineers, who have worked on complex optimisation tasks for a certain time, in a computational framework composed of machine learning and optimisation strategies. We aim at developing cutting-edge optimisation algorithms that can continuously accumulate experience by learning from development projects both over time and across different problem categories. The more such algorithms are used for different optimisation problems, the better they become since their accumulated experience increases. The Consortium consists of two world-leading universities, the University of Birmingham (UK) and the University of Leiden (The Netherlands), both in the top 150 in the 2016-17 Times Higher Education World University Rankings, and two innovative companies, Honda Research Institute Europe GmbH (Germany) in the automotive sector and NEC Europe Ltd (UK) in the ICT sector. All have world-leading research groups with complementary expertise that support ECOLE. ECOLE fills an urgent need in Europe for highly skilled optimisation and machine learning experts who have first-hand industrial experiences allowing sustainable know-how growth for solving future challenges. Its entire training programme is centred around a set of novel research projects proposed for early stage researchers (ESRs), complemented by domain knowledge training, hands-on engineering training and transferable skill training. ESRs will spend 50% of their time in the non-academic beneficiaries and be trained in different academic environments and industrial sectors.", "To": ["2022-03-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-04-01"], "Project_ID": ["766186"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN", "EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH", "PAUL SCHERRER INSTITUT", "HELSINGIN YLIOPISTO", "UNIVERSITY OF LEEDS", "LEIBNIZ INSTITUT FUER TROPOSPHAERENFORSCHUNG e.V.", "IONICON ANALYTIK GMBH", "UNIVERSITAT WIEN", "KARLSRUHER INSTITUT FUER TECHNOLOGIE", "TOFWERK AG"], "EU_Contribution": ["EUR 3 919 734,36"], "Project_Title": ["CLOUD-MObility, Training and InnOvation Network"], "Total_Cost": ["EUR 3 919 734,36"], "Country": ["Germany", "Switzerland", "Switzerland", "Finland", "United Kingdom", "Germany", "Austria", "Austria", "Germany", "Switzerland"], "Project_ACR": ["CLOUD-MOTION"], "Technology_Description": "The aim of CLOUD-MOTION is to establish a network of early stage researchers (ESRs, all PhD students) at 10 institutions across Europe. The role of aerosol nucleation and ice nucleation for atmospheric aerosol, clouds and climate is investigated.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-09-01"], "Project_ID": ["764991"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["UNIVERSITY OF HULL", "NOVA ID FCT - ASSOCIACAO PARA A INOVACAO E DESENVOLVIMENTO DA FCT", "UNIVERSIDADE ABERTA", "UNIVERSITEIT UTRECHT", "UNIVERSITAET GRAZ", "UNIVERSITE DE TECHNOLOGIE DE TROYES", "UNIVERSITA DEGLI STUDI DI MESSINA", "UNIVERSITA DEGLI STUDI GABRIELE D'ANNUNZIO DI CHIETI-PESCARA"], "EU_Contribution": ["EUR 3 854 797,56"], "Project_Title": ["CiRcular Economy: SusTainability Implications and guidING progress"], "Total_Cost": ["EUR 3 854 797,56"], "Country": ["United Kingdom", "Portugal", "Portugal", "Netherlands", "Austria", "France", "Italy", "Italy"], "Project_ACR": ["CRESTING"], "Technology_Description": "CRESTING will train Early Stage Researchers (ESR) in cutting edge systematic analysis of the process of transformation to a Circular Economy (CE). Establishing a CE (such that the maximum value is extracted from materials and waste generation minimised) is a major policy area within the European Union and elsewhere. Explicitly seen as increasing economic competitiveness and laying a foundation for environmental employment, CE policies are designed to increase resource efficiency and decrease carbon dependency. Previous and ongoing research into the CE, however, has been largely concerned with strategies for implementation. The many different fields of activity comprising the CE (e.g., re-use, recovery, recycling, eco-design amongst others) operate with varying degrees of effectiveness in different places and for different materials. These fields of activity have not been critically analysed as an interrelated social, technical, environmental and, significantly, spatial phenomenon. This programme will advance the critical analysis of the concept and sustainability implications of the CE by the training of 15 ESR analysing CE-related activity and initiatives in a range of geographic and economic settings. CRESTING is divided between 5 work packages (WP) analysing: current discourse and policy contexts (WP1); corporate engagement with the CE (WP2); public sector engagement in the CE (WP3); the potential for local economic development and employment from the CE (WP4); and measuring life cycle impacts and developing sustainability indicators relevant to the CE (WP5). With multidisciplinary and international supervisory teams including non-academic partners within each WP, CRESTING will 1) analyse the sustainability implications of the CE; 2) analyse the spatial dimension of the CE and 3) translate these analyses into specific actions for managing the transformation to the CE.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["765198"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["KATHOLIEKE UNIVERSITEIT LEUVEN", "DOSEVUE", "UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.", "ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM", "INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM"], "EU_Contribution": ["EUR 3 932 775"], "Project_Title": ["ACOUSTIC MARKERS FOR ENHANCED REMOTE SENSING OF RADIATION DOSES"], "Total_Cost": ["EUR 3 932 775"], "Country": ["Belgium", "Belgium", "Italy", "Germany", "Netherlands", "Belgium"], "Project_ACR": ["AMPHORA"], "Technology_Description": "Approximately 50% of all cancer patients receive radiation therapy as part of their treatment. The aim is hereby to maximise tumor irradiation and to minimize healthy tissue irradiation. This implies a need for appropriate dosimetry strategies that can effectively measure the actual radiation dose imparted on the tumor. However, state-of-the-art dosimetry cannot quantify the dose distribution in (and around) the tumor, hereby inhibiting the full potential of radiotherapy.", "To": ["2021-10-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-01-2016-2017 - FET-Open research and innovation actions"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2017-11-01"], "Project_ID": ["766456"], "Call_for_Proposal": ["H2020-FETOPEN-1-2016-2017"]}, -{"Partners": ["UNIVERSITY OF PLYMOUTH", "UNIVERSITY COLLEGE LONDON", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "STOCKHOLMS UNIVERSITET", "KAROLINSKA INSTITUTET", "ISTITUTI FISIOTERAPICI OSPITALIERI", "UNIVERSITA DEGLI STUDI DI CATANIA", "SCRIBA NANOTECNOLOGIE SRL", "MEDICAL TRIALS ANALYSIS ITALY SRL", "The Hyve B.V.", "STICHTING KATHOLIEKE UNIVERSITEIT", "KATHOLIEKE UNIVERSITEIT LEUVEN"], "EU_Contribution": ["EUR 3 687 311,88"], "Project_Title": ["An Integrated Platform for Developing Brain Cancer Diagnostic Techniques"], "Total_Cost": ["EUR 3 687 311,88"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom", "Sweden", "Sweden", "Italy", "Italy", "Italy", "Italy", "Netherlands", "Netherlands", "Belgium"], "Project_ACR": ["AiPBAND"], "Technology_Description": "The mission of AiPBAND is to train a new generation of entrepreneurial and innovative early-stage researchers (ESRs) in the early diagnosis of brain tumours using molecular biomarkers in the blood, meeting the medical and societal challenges of this emerging field. AiPBAND will focus on gliomas, a range of devastating and progressive brain tumours affecting around 25,000 people each year in Europe and responsible for the majority of deaths from primary brain tumours.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["764281"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Microdosimetry study of a new radiation therapy method based on proton minibeams"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["u-PBeam"], "Technology_Description": "Radiotherapy (RT) is the medical use of ionising radiation to treat cancer. The main challenge is to deposit a high enough (curative) dose in the tumor while risk organs near the tumour remain at tolerable doses. About 52% of cancer patients receive RT at least once during treatment. The RT has achieved great success in the cure or palliation of various cancers, but for improving this statistic, new treatment modalities as proton radiotherapy (PT) are rapidly expanding. PT achieves very high dose conformity around the target, allowing a better protection of the organs at risk (decreasing radiation side effect). However, using PT the dose delivered to a tumour is still conditioned by the dose that can be tolerated by the surrounding normal tissues. This is particularly critical for certain types of radioresistant tumours, such as hypoxic tumors, for those localized near organs at risk or sensitive structures (e.g. the spinal cord), and paediatrics cancers. For these types of cancers with poor prognosis it is imperative to find new RT approaches that reduce the normal tissue complication probability (NTCP). A recent novel therapy aim to increase the effective dose therapies by using a distinct dose delivery method based on proton minibeams (pMBRT). To implement this promising technique at clinical centers, microdosimetric data are required on the radiation quality aspects of proton minibeams to take advantage of their enhanced relative biological effectiveness versus conventional radiotherapy sources. Currently there are only one array of microdosimeters, as the proposed herein, capable of measuring these parameters in proton therapy. This is the challenge where a candidate approach is preferred.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2017-10-01"], "Project_ID": ["745109"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["A General Strategy for the Iterative Assembly of Complex 1,3-Polyol Motifs"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["GRITAP"], "Technology_Description": "An attractive approach to preparing molecules with common repeat units is iterative synthesis, an approach that is extensively used by Nature in the synthesis of large biomolecules. Nature also uses this tactic for small-molecule synthesis even though common repeat units are not always immediately apparent, the archetypical example being polyketide synthesis. In contrast, iterative strategies in chemical synthesis are often much less efficient requiring several functional-group interconversions and purifications between chain-extension steps. We recently reported an \u201cAssembly Line Synthesis\u201d method for the iterative, reagent-controlled homologation (chain extension) of a boronic ester. This process enabled the conversion of a simple boronic ester into a molecule bearing 10 contiguous methyl substituents in an effectively \u201cone-pot\u201d process. Whilst these methyl-rich carbon chains are rare in natural products, hydroxyl-rich carbon chains (1,3-polyols) are ubiquitous and often show pronounced and useful biological activity. It would therefore be very useful if this or a related strategy could be applied to the fully stereocontrolled synthesis of 1,3-polyols. Herein, we outline a general strategy for the synthesis of 1,3-polyols that hinges on the merging of two well-established methodologies: lithiation\u2013borylation and catalytic diboration. We expect to achieve complete control over both relative and absolute stereochemistry in the iterative synthesis of 1,3-polyboronic esters, enabling stereochemistry to be essentially dialled-in. Subsequent oxidation of the boron esters reveals the desired 1,3-related polyol. The strategy will be applied to the total synthesis of one of the most complex polyols known, bahamaolide A, a macrocyclic polyol\u2013polyene natural product with potent antifungal properties. This strategy promises to be the most efficient synthetic route to these highly biologically active and hugely important class of compounds.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["746045"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE DE LIEGE", "THE HEBREW UNIVERSITY OF JERUSALEM", "UNIVERSITA DEGLI STUDI DI PADOVA", "CONSIGLIO NAZIONALE DELLE RICERCHE", "KILOLAMBDA TECHNOLOGIES LTD", "PROBAYES SAS"], "EU_Contribution": ["EUR 2 993 640"], "Project_Title": ["Coherent Optical Parallel Computing"], "Total_Cost": ["EUR 2 993 640"], "Country": ["Belgium", "Israel", "Italy", "Italy", "Israel", "France"], "Project_ACR": ["COPAC"], "Technology_Description": "COPAC is a transformative novel area in computing both because of the technology, coherent information transfer by ultrafast laser addressing of engineered quantum dots, QD, arrays and because of the specialized parallel processing of large amounts of information. We will make foundational experimental, theoretical and algorithmic innovations to demonstrate a new technological paradigm for ultrafast parallel multi-valued information processing. We aim to develop a ground-breaking nonlinear coherent spectroscopy combining optical addressing and spatially macroscopically resolved optical readout to achieve unprecedented levels of speed, density and complexity. Two key high-risk / high-reward pioneering elements are the quantum engineered coherent concatenation of units and the multidirectional optical detection. Experimental demonstrations on tailored multilayer QD arrays of increasing complexity, integration into a device and novel hardware and matched compilers will be delivered. Preliminary experimental demonstrations of the response of solutions and of QD films are available as is the validation of logic operation in parallel.", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-01-2016-2017 - FET-Open research and innovation actions"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-11-01"], "Project_ID": ["766563"], "Call_for_Proposal": ["H2020-FETOPEN-1-2016-2017"]}, -{"Partners": ["UNIVERSITY OF GLASGOW", "BAYERISCHE JULIUS-MAXIMILIANS UNIVERSITAT WURZBURG", "UNIVERSITAET DUISBURG-ESSEN", "UNIVERSIDADE DO ALGARVE", "NPL MANAGEMENT LIMITED", "UNIVERSITAT AUTONOMA DE BARCELONA", "UNIVERSITE DE MONTPELLIER", "TECHNISCHE UNIVERSITAET WIEN", "CONSIGLIO NAZIONALE DELLE RICERCHE", "KEYSIGHT TECHNOLOGIES BELGIUM"], "EU_Contribution": ["EUR 3 866 553,36"], "Project_Title": ["Doctoral Training Network in Terahertz Technologies for Imaging, Radar and Communication Applications"], "Total_Cost": ["EUR 3 866 553,36"], "Country": ["United Kingdom", "Germany", "Germany", "Portugal", "United Kingdom", "Spain", "France", "Austria", "Italy", "Belgium"], "Project_ACR": ["TeraApps"], "Technology_Description": "Our future world will be one of ubiquitous sensor systems - a \u201cReal World Web\u201d where billions of devices, machines, or \u201cthings\u201d will connect to the internet. In 2008, more machines were connected to the internet than there are humans on the planet, and by 2020 there are predicted to be 50 billion machines connected to the internet. As a consequence, there will be an ever-increasing hunger for communications bandwidth, both at a local level within an office or apartment, and at nodes within data centres and server farms. The terahertz (THz) band is yet to be exploited, and occupies frequencies from 0.3 to 3 GHz (1mm to 100um) occupying a middle ground between microwaves and infrared light. THz technologies are also set to revolutionize a range of imaging, sensing, and quantum optics applications.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-01-01"], "Project_ID": ["765426"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["Fundaci\u00f3 Institut d'Investigaci\u00f3 Biom\u00e8dica de Bellvitge"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Activation of PI3K signalling in the pathogenesis of Vascular Anomalies"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["PI3K-VAs"], "Technology_Description": "Vascular anomalies are rare soft tissue tumours and malformations formed by abnormal vascular elements of various types, and mainly affect infants, children and young adults. These lesions are painful, many lead to bleeding, infections, organ dysfunction, and they can damage and metastasise to other tissues. Current treatment strategies are invasive, not fully efficient, and there is a high risk of recurrence. To date no specific targeted therapies have been developed. Most of the studies on vascular anomalies are descriptive and focused on their clinical aspects; at the moment, there is a lack of molecular understanding and pre-clinical studies on the field of vascular anomalies. Thus, identifying the causative molecular alterations of vascular anomalies and understanding their biology will lead to more refined diagnoses and will provide better and more directed therapies. Recent published and unpublished observations from our laboratory show that activation of phosphoinositide 3-kinase (PI3K) signalling pathway drive to the developments of a fraction of vascular anomalies; however, the underlying molecular and cellular mechanisms remain enigmatic. In this proposal we aim to (i) unveil alterations in the PI3K signalling pathway components that are involved in the pathogenesis of vascular anomalies, (ii) understand the role of PI3K pathway activation in the development and maintenance of these lesions, and (iii) explore the potential of repurposing PI3K pathway inhibitors for these conditions. For this, we have set up collaboration with clinicians who will provide a large collection of vascular anomalies from patients. Also, in collaboration with Pharma, we aim to use PI3K inhibitors for these diseases. Importantly, these collaborations will allow us to translate our findings into the clinic for future clinical trials. This project proposal seeks to broad our understanding of PI3K activation in vascular biology and to ultimately improve patients\u2019 quality of life.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2018-09-01"], "Project_ID": ["749731"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KUNGLIGA TEKNISKA HOEGSKOLAN", "ASTON UNIVERSITY", "BIOENERGY 2020+ GMBH", "FUNDACION CENER-CIEMAT", "ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS", "STICHTING WAGENINGEN RESEARCH", "STICHTING ENERGIEONDERZOEK CENTRUM NEDERLAND", "AGENZIA NAZIONALE PER LE NUOVE TECNOLOGIE, L'ENERGIA E LO SVILUPPO ECONOMICO SOSTENIBILE", "KARLSRUHER INSTITUT FUER TECHNOLOGIE", "Laboratorio Nacional de Energia e Geologia I.P.", "POLITECNICO DI TORINO", "STIFTELSEN SINTEF", "TECHNISCHE UNIVERSITEIT DELFT", "TECHNISCHE UNIVERSITAET GRAZ", "Teknologian tutkimuskeskus VTT Oy"], "EU_Contribution": ["EUR 9 968 144"], "Project_Title": ["Biofuels Research Infrastructure for Sharing Knowledge II"], "Total_Cost": ["EUR 9 977 271,01"], "Country": ["Sweden", "United Kingdom", "Austria", "Spain", "Greece", "Netherlands", "Netherlands", "Italy", "Germany", "Portugal", "Italy", "Norway", "Netherlands", "Austria", "Finland"], "Project_ACR": ["BRISK II"], "Technology_Description": "The vision of BRISK II is to establish a centre of excellence in the field of 2nd and 3rd generation biofuels via the uniting of leading European research infrastructures. Building upon the success of its FP7 predecessor, BRISK II Networking Activities will consolidate knowledge in the field, reaching out to a wide set of stakeholders and potential users. Databases generated within the project will serve as a valuable resource for academia and industry. The business plan will boost momentum beyond H2020 so that the research infrastructures can be utilised between framework programmes or even independently. Joint Research Activities will yield a manifold improvement in the characterisation of feedstocks for thermochemical and biochemical conversion processes, tying micro-scale and macro-scale phenomena in novel ways. Enhanced measurement techniques will lead to significant gains in process flexibility and reliability. New biorefining approaches are intended to explore novel process combinations, ones that cannot be tested without a concerted effort between project partners. Assimilated data and knowledge will be input to simulation tools for use in a broad spectrum of analyses. Transnational Access supports the biofuels research community through the availability of high-quality installations within a well-structured framework.", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["INFRAIA-01-2016-2017 - Integrating Activities for Advanced Communities"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2017-05-01"], "Project_ID": ["731101"], "Call_for_Proposal": ["H2020-INFRAIA-2016-1"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Design of Hyper Tall Onshore Wind Turbine Towers"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["HYPER TOWER"], "Technology_Description": "\"HYPER TOWER is a very promising project that will lead to a radical increase in the wind turbine tower height and consequently to an increase in the energy potential harvested by wind structures. The project reaches its aims of constructing taller, more robust and economical towers by realizing 6 work packages that are formulated and developed in 2 years. In approaching the \"\"20-20-20\"\" targets, more and more energy has to come from sustainable energy sources and since \"\"The taller the wind tower is, the greener the energy is\"\", a constant trend of taller wind energy structures is observed. The civil engineers' challenge of constructing taller structures, with heavier machinery hanging at greater heights has led to the need of evolution of a new tower configuration that can reassure the structure's robustness along with a feasible construction schedule.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["747921"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF LEEDS"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Testing communication strategies to save lives in emergency evacuation"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["EVACUATION"], "Technology_Description": "The EU urgently seeks to improve emergency evacuation preparedness. EU public spaces are getting more crowded. Fires and terrorist attacks require emergency evacuation. Faster evacuation from public buildings during emergencies saves more lives. Observations of actual emergencies show that people tend to be slow to respond to evacuation alarms (taking up to 10 minutes) and take the familiar route out instead of the nearest exit. The EU calls for evidence-based recommendations for evacuations, which are mostly non-existent. The state of the art uses computer models of evacuation speed, but more realism is needed. We take the novel approach of combining state of the art computer modeling with insights from risk communication to improve speed and survival in emergency evacuations. This project aims to: ", "To": ["2020-02-29, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["748647"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FREIE UNIVERSITAET BERLIN"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Characterisation method for spin-dependent processes in solar energy technology"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["SpinSolar"], "Technology_Description": "In the search for renewable energy sources, solar energy shows great promise through its conversion to electricity and storable fuels using artificial photosynthesis. A detailed understanding of the energy conversion processes on the nanoscale is needed for the rational design and improvement of solar technology. This project is aimed at the development of a methodology for in-depth characterisation of spin-dependent processes in solar energy devices. The method will be based on a novel combination of pulse Electron Spin Resonance (ESR) and Electrically Detected Magnetic Resonance (EDMR) spectroscopy with arbitrarily shaped pulses. ESR by itself has already proven to be instrumental for advancing the understanding of natural photosynthesis and the increased sensitivity of EDMR allows the extension of this technique to assembled devices.", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["743419"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI TORINO", "UNIVERSITA DEGLI STUDI DEL PIEMONTE ORIENTALE AMEDEO AVOGADRO", "AALBORG UNIVERSITET", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "ECOLE POLYTECHNIQUE", "KARADENIZ TEKNIK UNIVERSITESI", "LIQTECH INTERNATIONAL A/S", "Societ\u00e0 Metropolitana Acque Torino S.p.A.", "CENTRO DE INVESTIGACIONES ENERGETICAS, MEDIOAMBIENTALES Y TECNOLOGICAS-CIEMAT", "PANEPISTIMIO IOANNINON", "UNIVERSITAT POLITECNICA DE VALENCIA"], "EU_Contribution": ["EUR 3 897 678,24"], "Project_Title": ["Interdisciplinar cross-sectoral approach to effectively address the removal of contaminants of emerging concern from water"], "Total_Cost": ["EUR 3 897 678,24"], "Country": ["Italy", "Italy", "Denmark", "France", "France", "Turkey", "Denmark", "Italy", "Spain", "Greece", "Spain"], "Project_ACR": ["AQUAlity"], "Technology_Description": "AQUAlity is a multidisciplinary and cross-sectoral European Training Network, that consist in eighteen participants (7 universities, 3 research institutes and 8 companies) and aims to generate and promote highly skilled scientists with the potential to face the present and future challenges concerning the protection of water resources from contaminants of emerging concern (CECs). AQUAlity will enroll fifteen early-stage researchers (ESRs) to conduct cutting-edge research on multidisciplinary aspects of novel hybrid technologies for the removal of CECs from aqueous systems. Moreover, ESRs will be trained to develop their creativity, critical and autonomous thinking, and entrepreneurial skills, thus boosting their scientific skills and innovation capacity in the field of water treatment technologies. This goal will be attained via a structured training-through-research programme, consisting of original individual research projects (performed both at the beneficiary organization and through intersectoral secondments) and education on technical and transferable skills (performed both at local level and with network-wide events). The overall research goal of AQUAlity is to develop highly innovative hybrid green technologies for CECs removal from aqueous systems by unconventional solar advanced oxidation processes (AOP) in combination with high flux ceramic nanofiltration membranes. Hence, ESRs will conduct frontier research in the field of AOP (organic photocatalysis, sensitized photocatalysts, photo-Fenton), materials development, nanofiltration technology, and will develop innovative hybrid photochemical/membranes systems to be tested on different waters to prove their potential for the production of high-quality water. Advanced analytical tools for the determination of CECs, their degradation products and water safeness will be developed. Thanks to the presence of industrial participants, AQUAlity aims for the commercial exploitation of part of the research results.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["765860"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["UNIVERSITEIT LEIDEN"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["Investigating the mechanisms that shape galaxies in and around massive clusters"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["ClusterGal"], "Technology_Description": "For decades, astronomers have known that some galaxies are living in dense associations known as \u201cgalaxy clusters\u201d, and that many of their properties, e.g. their morphology, colour, and gas content, differ from those of galaxies living in more isolated parts of the Universe (like our Milky Way). However, understanding the physical origin of these differences has so far proved elusive, constituting a major gap in our understanding of galaxy formation.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["747645"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["USTAV PRO SOUDOBE DEJINY AV CR V.V.I"], "EU_Contribution": ["EUR 142 720,80"], "Project_Title": ["Articulating the free market: A cultural history of the economic transformation in Central Europe, 1989-1999"], "Total_Cost": ["EUR 142 720,80"], "Country": ["Czech Republic"], "Project_ACR": ["ATFM"], "Technology_Description": "This project excavates how cultural production was influenced by and interacted with the introduction of free market mechanisms in Central Europe after 1989. Concentrating specifically on the 1990s, it argues that this decade now deserves to be studied historically, rather than being understood as part of a present \u201cpost-communist\u201d condition. The collapse of state socialism and (re)instatement of democracy has been theorised from an economic, political, and social perspective, but its significance for cultural production has been neglected. This project analyses how this economic change was perceived and rooted in society through cultural representations. Specifically, it investigates how the fields of cinema and television responded to the introduction of a free market economy in Poland, Czech Republic, and Slovakia. Its main object of investigation is the reciprocal relationship between the effects of economic change on cultural production and this production as an agent in economic change. The proposed research will attend to the cultural dimension of the economic transformation in order to understand the symbolic meanings and narratives that gave the economic and political changes coherence and social validity at the time. ", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Czech Republic"], "Activity": ["Research Organisations"], "From": ["2018-02-01"], "Project_ID": ["749475"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM"], "EU_Contribution": ["EUR 144 000"], "Project_Title": ["Surface Promoted Enhanced Transport of Li-ions"], "Total_Cost": ["EUR 144 000"], "Country": ["Belgium"], "Project_ACR": ["SUPER-Lion"], "Technology_Description": "As a rechargeable energy source lithium ion batteries (LIB) with a solid-state electrolyte is a highly desired option compared to LIB with liquid electrolytes due to several advantages, such as improved safety and extended lifetime, in addition to enabling devices with both high energy and power densities. However, despite an extensive research effort in this field development of all-solid-state batteries have not yet started to reached its full potential, largely because of the lack of suitable electrolyte candidate materials that offers both high ionic conductivity and good electrochemical stability. We propose, within SUPER-Lion, the use of a novel nano composite electrolyte (NCE) that would enable solid-state LIB to reach their full potential, achieving both high ionic conductivities, combined with good mechanical and electrochemical stability. The NCE consists of a nanoporous insulator that provides both mechanical stability and a high effective internal surface area. The internal surface of the nanoporous matrix is coated with nanometer thin layers of a lithium salt that supply the necessary Li+ ions. The enhanced ion transport at the interface between the surface of the insulator and the lithium salt is exploited to make a NCE with high ion conductivity. By exploiting the effect of nanoconfinment the ionic conductivity of such interfaces can be enhanced by several orders of magnitude through an effect described as superionic transitions. The NCE will be manufactured through the combination of atomic layer deposition (ALD) and molecular layer deposition (MLD). Due to the self-limiting nature of the ALD/MLD technique it is perfect for deposition of thin layers where uniformity, subatomic thickness control and high quality films are of utter most importance. The ALD/MLD technique also enables the NCE to be deposited on 3D structured electrodes with high aspect ratios, thus enabling a further increase in the power and energy density of all-solid state batteries.", "To": ["2018-11-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Belgium"], "Activity": ["Research Organisations"], "From": ["2017-03-15"], "Project_ID": ["752716"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Novel smart glyco-nanomaterials as targeted therapeutics."], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["Glyco-Platforms"], "Technology_Description": "Cell surface carbohydrates play key roles in cell recognition mechanisms. Protein-carbohydrate interactions typically exhibit high specificity and weak affinities toward their carbohydrate ligand. This low affinity is compensated in nature by the architecture of the protein, the host presenting the carbohydrate ligands in a multivalent manner or as clusters on the cell or mucosal surface. O-glycosylation is a ubiquitous post-translational modification that is highly dynamic and responsive to cellular stimuli through the action of the cycling enzymes. Expression of specific O-glycans is linked to changes in gene expression in, for example, inflammatory bowel disease, cystic fibrosis and several types of cancer. Understanding these glycosylation patterns at molecular and functional levels will allow mechanisms associated with bacterial-host interactions, bowel disease and other cancers to be defined, which will facilitate the development of new effective therapeutics and diagnostic tools for these conditions. The proposal centers on the chemo-enzymatic synthesis of novel multivalent mucin-type O-glycan probes for the screening of O-glycosylation-linked interactions in health and in disease and the development of smart glyco-nanoparticles as drug delivery systems. This is a multidisciplinary project involving synthetic organic and inorganic chemistry and glycobiology.", "To": ["2019-10-09, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-10"], "Project_ID": ["748103"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Artificial Life TodayAnthropological and Sociological Analysis of Life Engineering"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["ARTENGINE"], "Technology_Description": "We are witnessing profound changes in our societies via biosciences and bio-technologization. Biotechnologies, synthetic biology, and new genetics in general represent key areas of life sciences, characterised by rapid technological and scientific development. The biotechnologies as key areas of contemporary cultural and social transformations are influenced by specific technological rationality and power that is inscribed in the very foundations of modern society. The power is biopower/biopolitics, which names, creates, and controls life. The project addresses contemporary challenges in the field of biopolitical life engineering, specifically in case of PGD (preimplantantion genetic diagnosis) technology. There is a lack of reflection on the broader social and cultural context and on the ramifications of synthetic life engineering, PGD in the Czech Republic from the anthropological and sociological points of view. These issues remain unanalysed, contributing to a lack of understanding of the specific concerns of synthetic life and life sciences in the Eastern European and post-socialist context. This proposed project will analyse social context of technology PGD in the Czech Republic in comparison with Germany. This project is guided by the main questions: How is the field of life engineering, particularly PGD technology, culturally and socially structured in the Czech Republic in comparison with Germany? What kinds and forms of agency are involved there? Are there any specific concerns in public debates relating to life engineering in comparisons of Eastern and Western Europe? The main aim of this research, which will be conducted on case studies of two European countries, is to analyse and interpret through sociological and anthropological perspective the ways in which current forms of biopower and ideas of artificial life have been influencing the social field of life engineering, especially PGD technology.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["750088"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Biodegradable Water-Soluble Cylindrical Block Copolymer Micelles and their Applications in Nanomedicine"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["JTIM"], "Technology_Description": "Block copolymer (BCP) self-assembly in solution has attracted considerable attention for many decades because it can yield ordered nanoscopic core-shell structures (micelles) with a wide range of morphologies. These aggregates offer potential applications in many fields, and cylinders are among the most promising for uses in nanomedicine (e.g. as drug delivery vehicles). In this proposal, state-of-the-art strategies to access well-defined micelles with tailored structures will be applied to the preparation of biodegradable monodisperse cylindrical micelles and block comicelles in water. Once formed, the micelles and their hierarchical assemblies will be characterized in detail and explored in potential nanomedical applications. To achieve these objectives Dr. Jia Tian, an exceptionally talented young scientist from China who performed his Ph.D. in a top supramolecular chemistry group in China (Zhan-Ting Li, Fudan University), will work in the internationally leading polymer and materials research group of Prof. Ian Manners (Bristol, UK) where he will learn polymer synthesis and state-of-the-art self-assembly techniques and will obtain a broad background in polymer and BCP synthesis, self-assembly, and polymer materials science. Armed with the new knowledge and experience gained, following the fellowship Dr. Tian aims to obtain an academic position in China where soft materials such as biodegradable BCPs and their applications in nanomedicine will play a key role.", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["750527"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Synthesis of sp3-Rich Organofluorine Compounds through Homologation of Boronic Esters"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["FOOTLOOSE"], "Technology_Description": "Organofluorine compounds are highly sought after owing to diverse and numerous applications that take advantage of the unique properties imparted by the presence of one or more C\u2013F bonds. The chemical stability and conformational landscape of molecules, together with the small size of the fluorine atom, has the made the replacement of a C\u2013H or C\u2013OH bond with a C\u2013F one of the most rewarding modifications during the hit-to-lead stage in medicinal chemistry programs. Because many applications are dependent on the absolute and relative configuration of the fluorine-containing group, methods that can introduce such groups in a stereoselective manner are particularly attractive. ", "To": ["2019-07-26, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-27"], "Project_ID": ["749862"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 251 857,80"], "Project_Title": ["Photo- And Radical induced Reactivity of Atmospheric Oxidants"], "Total_Cost": ["EUR 251 857,80"], "Country": ["United Kingdom"], "Project_ACR": ["PhARRAO"], "Technology_Description": "The research program will seek to explore the mechanisms and formation/reaction rates of various oxidizing agents pertinent to tropospheric chemistry, using cutting-edge experimental apparatuses and theoretical methods. ", "To": ["2020-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["746593"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["TECHNISCHE UNIVERSITEIT DELFT"], "EU_Contribution": ["EUR 151 798,90"], "Project_Title": ["Asynchronous Time-domain Neural Recording Interfaces"], "Total_Cost": ["EUR 151 798,90"], "Country": ["Netherlands"], "Project_ACR": ["ATiNaRI"], "Technology_Description": "Implantable neural recording devices are being used by neuroscientists and neurosurgeons for monitoring the behaviour of particular parts of the brain. With the advancement of microelectronics manufacturing processes, wireless multi-channel neural recording systems have become available during the last decade. However, the capabilities of neural recording implants are still limited by their power density in order not to harm the surrounding tissue by heat generation, and by their total power consumption which limits the operational longevity of the implant. If the operational capabilities and longevity of the neural recording implants are to be improved, new methods of power consumption reduction are required.", "To": ["2019-07-17, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-18"], "Project_ID": ["752819"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["The impact of literary translation funding on the transnational mobility of minor European literatures."], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["Apricale"], "Technology_Description": "This project will investigate the rationale, function and impact of funding for the translation, publication and promotion of European literature. State, supranational and third-sector structures for funding translations have been in place for several decades across Europe, promoting literary and cultural diversity. Applying sociological tools to translation, literary and cultural studies, this research will analyse how recent and current schemes inform practical decisions on acquisition, publishing and marketing strategies by target publishers across multiple European countries.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["749871"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Advanced Ecosystem for Broad Heterogeneous Memory Usage"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["ECO-H-MEM"], "Technology_Description": "Supercomputers are a key tool for professionals from many disciplines to address society challenges, enabling them to perform, e.g., climate change simulations or genome analysis. EC\u2019s HPC Strategy, implemented in H2020, devises the need to bring Europe's high-performance computing technology to the exascale era, being energy efficiency one of the major challenges. Since providing the required amount of memory for upcoming exascale applications is non-viable by means of top-performance technology only, due to energy consumption and dissipation constraints, vendors are incorporating a variety of additional memory subsystems built upon different technologies, which provide diverse features and limitations (e.g., Intel\u2019s Knights Landing processor). Deciding what data to host in each memory subsystem is far from trivial and poses notable performance implications. Recent research has focused on their use for specific purposes such as resilience or to host selected data objects based on some basic criteria. The aim of this project is to move a big step forward and develop technology to build an innovative generic software ecosystem to facilitate the efficient use of heterogeneous memory systems, what will be crucial to leverage the full potential of exascale platforms. BSC is an excellent institution to develop this research because of its top-level facilities and researchers, its multiple collaborations with industry, and the exceptional training, dissemination, and communication opportunities it offers. While Prof. Ayguad\u00e9 will supervise this fellowship bringing the experience of a brilliant consolidated career and leading roles in European projects, technology transfer to Intel will boost the impact of the project. This undoubtedly represents an outstanding opportunity for the candidate to complement his GPU Computing experience, consolidating his research career in system software for many-core architectures while reintegrating in a long-term position in Europe.", "To": ["2020-02-29, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2018-03-01"], "Project_ID": ["749516"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Stereoregular Inorganic Polymer Analogues of Polyolefins"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["VAIM"], "Technology_Description": "Inorganic polymers are of great interest as a result of their interesting properties, which offer exciting opportunities for their use as functional materials. Currently inorganic polymers generated through dehydrocoupling of group 13/15 amine- or phosphine-borane adducts are atactic and lack crystallinity, precluding their use in a variety of applications. The proposed research targets stereoregular polyaminoboranes and polyphosphinoboranes, inorganic analogues of stereoregular polyolefins, and potentially block copolymers, through catalytic dehydropolymerization using chiral earth abundant transition metal catalysts. The stereoregular polymers and block copolymers will be characterized in detail, and potential applications explored. To achieve these objectives a highly talented young scientist, Dr. Vincent Annibale, wishes to work in the highly multidisciplinary and internationally leading research group of Prof. Ian Manners at the University of Bristol for 2 years. Dr. Annibale has a wealth of expertise in synthetic transition metal chemistry from his previous postdoctoral and Ph.D. work. With a Marie Sklodowska Fellowship Dr. Annibale would gain exceptionally valuable experience and would become proficient in the field of polymer and materials science, which would be extremely important for his future career, preferably in academia, or in industry.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["748371"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF LEEDS"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Living Well: Provisioning Systems for Sustainable Resource Use and Human Well-Being"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["LIVEWELL"], "Technology_Description": "Humanity faces the challenge of how to achieve a high level of well-being for all people without destabilizing the planetary processes that facilitated the rise of civilization. This project revolves around the intermediating role of physical and social provisioning systems that link resource use and social outcomes. Provisioning systems mediate the relationship between biophysical inputs and social outcomes via the material practices and cultural meanings associated with the consumption of specific commodities (i.e. energy, housing, transport, etc.). A better understanding of provisioning systems can provide insight on how to achieve high levels of well-being at low levels of resource consumption that are within planetary boundaries.", "To": ["2019-10-01, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-02"], "Project_ID": ["752358"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF DURHAM"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["fault STRength breAkdown and Implications for earthquake Nucleation"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["STRAIN"], "Technology_Description": "Our ability to limit the societal and economic impact of the earthquakes is strongly tied to our understanding of the physics lying behind the earthquake phenomenology. Most earthquakes are generated along pre-existing faults that suddenly fail after prolonged periods of tectonic stressing. Indeed, an earthquake is generated by the imbalance between the elastic energy provided by the rocks surrounding the fault and the strength drop of the fault itself, which is degraded by progressive slip. A large number of experimental and geophysical data well characterize the first-order resistance of the rocks either before (\u201cstatic\u201d strength) or after the initiation of seismic slip (\u201cdynamic\u201d strength). However, there is a fundamental lack of understanding about how exactly the fault strength decrease slip (STRAIN weakening) and about the real elasticity of the rock masses around the fault, i.e. the \u201cspring\u201d that triggers the earthquakes. We propose the first systematic study of the changes in rock strength with progressive strain using two world-class deformation apparatuses hosted at Durham University, integrating a wide range of microstructural observations and lab seismology techniques to have insights into the microphysics of deformation. We also propose to acquire an unprecedented dataset on the elasticity of fault rocks at in situ conditions, which will be combined with shear experiments to produce empirically calibrated models of fault zone that may shed new light on the process of earthquake nucleation and of potential seismic precursors.", "To": ["2019-09-10, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-11"], "Project_ID": ["748400"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Geometric and analytic aspects of isoparametric hypersurfaces"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["ISOPARAMETRIC"], "Technology_Description": "Isoparametric hypersurfaces are intriguing geometric objects whose study has revealed connections with several areas of mathematics and mathematical physics, and which have typically been investigated with differential geometric, algebraic or topological techniques.", "To": ["2019-04-15, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-04-16"], "Project_ID": ["745722"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Development of highly efficient and stable organic light-emitting diodes based on delayed fluorescent materials for solid-state lighting applications"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["THF-OLED"], "Technology_Description": "At present, OLED technology is expected to be practically applied to flat panel displays and solid state lighting sources because of its unique characteristics of low-cost processing, flexibility, and low power consumption. Till date, a large number of fluorescent and phosphorescent materials have been developed to improve the electroluminescence (EL) efficiency of OLEDs. As a result, highly durable and practically applicable OLEDs using these materials have been realized. However, the internal quantum efficiency of OLEDs based on fluorescent materials is only 25% because of the limit imposed by the electron spin-statistics under electrical excitation. In contrast, OLEDs using phosphorescent materials based on luminescence from the triplet state can achieve 100% internal quantum efficiency. Recently, an alternative realistic approach, called thermally activated delayed fluorescence (TADF), has been established to obtain ultimate 100% internal EL quantum efficiency in organic light-emitting diodes (OLEDs). But owing to rather a long transient lifetime of the triplet excited states, high efficiency roll-off and low operational stability at high current density are pertaining concerns in TADF based OLEDs. To address these challenges, the present state-of-the-art TADF-OLED technology uses a TADF molecule as an assistant dopant and a fluorescent molecule as an end emitter in a host matrix, called TADF assisted fluorescence (TAF-OLED). However, TAF-OLED approach has several inherent technical challenges associated with device physics, fabrication and cost. Through this research proposal we present a more simplified and realistic approach, called TADF hosted fluorescence (THF), to enhance the performance and operational stability by using TADF material as host material and fluorescent molecule as end emitter eliminating the need of external host matrix thus mitigate the technical issues associated with TAF-OLEDs.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["748430"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN"], "EU_Contribution": ["EUR 239 860,80"], "Project_Title": ["Linguistic Dimensions of Sexual Normativity"], "Total_Cost": ["EUR 239 860,80"], "Country": ["Germany"], "Project_ACR": ["LIDISNO"], "Technology_Description": "LIDISNO is the first large-scale research project that analyses the role of language in the discursive formation of sexual normativity. Based on poststructuralist and Queer Linguistic theorisations of language and sexuality as discursively shaped, the project highlights the historical relativity and variability of sexual normativity by adducing empirical linguistic evidence from various time periods. In contrast to earlier work, which has largely postulated sexuality-related discursive shifts without verifying them in larger amounts of linguistic data, LIDISNO uses corpus linguistically informed critical discourse analysis to study the linguistic corollaries of three sexuality-related normative shifts: 1. language use about a person before and after their public coming out, with US Latino pop singer Ricky Martin as a case study, 2. language use to express same-sex experiences pre- vs. post-Stonewall, and 3. sexuality-related language use before and after 1890, i.e. the time of the oft-cited desire-to-identity shift in the conceptualisation of sexuality. Each of these shifts is studied through comparisons of pairs of text corpora pre- and post-dating the respective shift, while drawing on quantitative and qualitative corpus linguistic methods (frequency of sexuality-related features, frequency lists, keyword lists, semantic keyness, concordances, collocations, colligations) with the help of the tools AntConc and Wmatrix. These linguistic analyses are complemented by a comparison of findings across corpus pairs and comparisons with various types of supplementary data (interviews, personal narratives, major English reference corpora). LIDISNO will improve our understanding how linguistic practices shape sexual normativity. Its findings will be used to advance the theorisation of normativity as an analytical tool in critical discourse studies and to devise language policies that foster greater tolerance and inclusion of non-heterosexual individuals.", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["740257"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["A combination of approaches from the molecular to the integrative plant level to understand the bases of stomatal responses to CO2 and their variability"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["STOCOVAR"], "Technology_Description": "Understanding plant responses to rising atmospheric CO2 is of major interest given the necessity to select and develop new crop cultivars that will perform better in a changing global climate. By regulating the exchange of water and CO2 between the interior of the leaf and the atmosphere, stomata -the pores at the leaf surface- play a major role in CO2-mediated processes. Stomatal aperture is constantly adjusted, in response to internal cues and external environmental signals, through turgor changes of the two guard cells that surround the pore. Plants respond to elevated CO2 levels by reducing stomatal aperture, and recent advances have shed light on the intracellular machinery responsible for this response. However, little is understood about the variability in stomatal responses to CO2, both among and within species. This project will decipher the main factors responsible for variations in stomatal responses to CO2. It will specifically address the roles of ABA-signalling, photosynthesis and stomatal morphology in the response of stomatal conductance (gs) to CO2 and how this impacts on plant performance. These will be investigated from the cellular to the level of the whole plant by using the model plant Arabidopsis thaliana and major European crops. Genetic diversity will be used in different forms (mutants, association studies, inter-specific comparison) to identify the causal factors of variation. The knowledge gained into gs responses will be integrated into predictive models for water-use efficiency to scale-up to whole plant performance.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["740222"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Shark extinctions: past and present"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SHARKS-XT"], "Technology_Description": "Species are going extinct at an accelerated rate. Yet, some species are more resilient than others. Understanding what determines species susceptibility to extinction is crucial to address species loss; however, current knowledge provides mixed clues. SHARKS-XT aims to study fossil and modern sharks to determine what factors can help predicting their extinctions; and to assess if modern sharks are responding differently to current extinction threats, or if the predictors of the past can aid conservation efforts. To reach our research objectives we propose three work packages (WPs) in which we will: (WP1) integrate what is currently known in palaeontology and neontology to create a comprehensive trait-dataset of all fossil and living sharks; and employ a novel combination of quantitative methods to establish the relative role and interactions between (WP2) intrinsic (traits) and (WP3) extrinsic (environment) factors in determining extinction susceptibility. We will then compare our results to assess if the predictors (or interactions between predictors) of extinction are consistent across different timescales. The strength of this proposal lies in the use of sharks as a model because they: (1) have an abundant fossil record that goes deep in geological time; (2) have shown resilience to major environmental changes in the past; (3) have lower extinction rates, (4) are being affected the most by the current biodiversity crisis; and (5) play key roles in stabilising marine systems. This research has the potential of assessing how far the rich resources of the fossil record may be used to address modern risks, and could have important societal impacts: by identifying predictors of shark extinction, the role of the climate in establishing such predictors, and the extent to which the predictors of the past can be used to address today\u2019s extinction crisis; it would be possible to re-focus conservation efforts.", "To": ["2020-05-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-06-01"], "Project_ID": ["745844"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ASTON UNIVERSITY"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Smart Modulation Methods for Energy Efficient Operation and Health Monitoring of Future Motor Drives"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SmaMoMeMoDs"], "Technology_Description": "The goal of this Fellowship, entitled \u201cSmart Modulation Methods for Energy Efficient Operation and Health Monitoring of Future Motor Drives\u201d (SmaMoMeDs) is to train an outstanding researcher (Dr Lassi Aarniovuori) with a strong academic background through a research project focused on the innovative modulation algorithms for a new technology wide-bandgap gallium nitride (GaN) and silicon carbide (SiC) based inverter bridges (power switches) that will be used in future motor drives. These new switches allow the use of ultra-high switching frequencies in motor drives, creating opportunities to improve the performance, reliability and energy-efficiency of the motor drives systems. The proposed smart modulation methods are aimed 1) to identify the motor parameters for the control system, 2) to optimize the modulation method according to the operating conditions, 3) to detect any changes in the mechanical or electrical behavior of the motor parameters for health monitoring. The applicant Dr. Aarniovuori will be trained in the field of electrical power engineering, power electronics, motors, and drives. These are the key components in any modern industrial applications and they are a part of people\u2019s everyday live in all welfare societies. The Fellow will get a unique training experience at the host \u2013 Aston University its industrial partner Jaguar Landrover (JLR)., its academic partners Newcastle University (UK) and Politecnic Torino (Italy).", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["746900"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 257 191,20"], "Project_Title": ["Towards a unified mechanistic model of oceanic island biogeography"], "Total_Cost": ["EUR 257 191,20"], "Country": ["Spain"], "Project_ACR": ["UNISLAND"], "Technology_Description": "Understanding how ecological and evolutionary processes shape patterns of biodiversity remains a central challenge for ecological and biogeographic theory. Oceanic islands, because of their spatiotemporal properties, provide the most promising arena to address this challenge. UNISLAND will advance general theory by applying novel ecological, evolutionary and genomics approaches to explicitly test mechanistic predictions derived from the recently developed General Dynamic Model (GDM). The GDM, while an island focused model, is of broad ecological relevance, because it encompasses generally held ecological relationships, such as the species area relationship (SAR) and the species abundance distribution (SAD). Two key mechanistic predictions derived from the GDM have so far been untested, and are the focus of UNISLAND. The first is that the older an island is, the more old are the single island endemic species (SIEs) that evolved on that island. The second is that single island endemic species (SIEs) have higher extinction probabilities that other species. UNISLAND is embedded in a multidisciplinary framework involving: comparative phylogenetics; community-level modeling; \u2018museum\u2019 genomics; and spatially-explicit coalescent-based analysis. Data generated by UNISLAND will evaluate the range shift and extinction risk (species-level and ecosystem-level), thus addressing international and European-level research priorities. Through the collaborative phase between the ER and OPS, UNISLAND will provide the ER with state of the art skills in historical DNA genomics and ecological modelling that will be transferred to the CSIC during the return phase. The complementary research profiles of the OPS, RPS and ER, their mutual interests in the spatial structuring of biodiversity, and the application of modern fit for purpose methodology, underpin the strength of UNISLAND.", "To": ["2020-09-15, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-09-16"], "Project_ID": ["747238"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Boron chemistry in a new light: exploring the radical reactivity of boronate complexes through photochemical strategies"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["PHOTO-BORAD"], "Technology_Description": "In the last decade photoredox reactions have emerged as tremendously versatile processes for organic synthesis, enabling reactive radical species to be generated at specific positions in an organic molecule under very mild conditions (visible-light irradiation). Over the same decade the host group have developed a suite of transformations exploiting the fundamental chemistry of boron, many of which involve 1,2-metallate rearrangement of boronate complexes. We now seek to merge these two major pillars of synthetic methodology, which are currently unconnected, to create a new field which we believe has significant potential for organic synthesis. ", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-03-01"], "Project_ID": ["744242"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITA' DEGLI STUDI DI SIENA", "VIRTUAL INSTITUTE FOR ARTIFICIAL ELECTROMAGNETIC MATERIALS AND METAMATERIALS - METAMORPHOSE VI AISBL", "NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.", "Teknologian tutkimuskeskus VTT Oy", "UNIVERSITA POLITECNICA DELLE MARCHE", "KING'S COLLEGE LONDON", "FUNDACIO INSTITUT CATALA DE NANOCIENCIA I NANOTECNOLOGIA", "I.D.S. - INGEGNERIA DEI SISTEMI - S.P.A.", "ECOLE SUPERIEURE DE PHYSIQUE ET DECHIMIE INDUSTRIELLES DE LA VILLE DEPARIS", "THALES SA", "POLITECNICO DI TORINO"], "EU_Contribution": ["EUR 670 000"], "Project_Title": ["NANOARCHITECTRONICS"], "Total_Cost": ["EUR 670 000"], "Country": ["Italy", "Belgium", "Netherlands", "Germany", "Finland", "Italy", "United Kingdom", "Spain", "Italy", "France", "France", "Italy"], "Project_ACR": ["NANOARCHITECTRONICS"], "Technology_Description": "This FET-open Coordination and Support Action is called \u201cNanoarchitectronics\u201d (NTX) to denote a new interdisciplinary research area at the crossroad of Electromagnetics and Nanoelectronics. NTX It is a new technology aimed at conceiving, designing and developing reconfigurable, adaptive and cognitive structures, sensorial surfaces and functional \u201cskins\u201d with unique physical properties, and engineering applications in the whole electromagnetic spectrum; through assembling building blocks at nanoscale in hierarchical architectures. The conception of this new area responds to the need of unifying concepts, methodologies and technologies in Communications, Environment Sensing Systems, Safety and Security, Bio-Sensing Systems and Imaging Nanosystems, within a wide frequency range. This FET project proposal gathers thirteen universities, research centers and high-tech industries, belonging to eight European countries. ", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-02-2016 - FET-Open Coordination and Support Actions"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["737135"], "Call_for_Proposal": ["H2020-FETOPEN-2-2016"]}, -{"Partners": ["ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE"], "EU_Contribution": ["EUR 2 492 036"], "Project_Title": ["Skill Acquisition in Humans and Robots"], "Total_Cost": ["EUR 2 492 036"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["SAHR"], "Technology_Description": "Society is rapidly opening its doors to robots in our daily life with autonomous vehicles, rehabilitation devices and autonomous appliances. These robots will face unexpected changes in their environment, to which they will have to react immediately and appropriately. Even though robots exceed largely humans\u2019 precision and speed of computation, they are far from matching humans\u2019 capacity to adapt rapidly to unexpected changes. In the past decades, robotics has made leaps forward in the design of increasingly complex robotic platforms to meet these challenges. In this endeavour, it has benefited from advances in optimization for solving high-dimensional constrained problems and in machine learning (ML) to analyse vast amounts of data. These methods are powerful for planning in slow-paced tasks and when the environment is known. This project addresses a growing need for methods that show fast and on-line reactivity. ", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["741945"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["TECHNISCHE UNIVERSITEIT EINDHOVEN", "TECHNISCHE UNIVERSITEIT EINDHOVEN"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Piloting cascaded continuous flow synthesis for the pharmaceutical industry"], "Total_Cost": ["EUR 150 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["PICASCO"], "Technology_Description": "PICASCO aims to deliver the commercial proof of concept of a novel endto- end flow manufacturing and a novel corresponding compact flow mini plant. This is performed through the first continuous 4-step solvent-free flow manufacturing of a pharmaceutically relevant API compound at an industrial scale. Currently applied batch manufacturing techniques leave much room for improved quality, efficiency, cost-effectiveness and environmental friendliness. Flow multi-step manufacturing can address all these issues simultaneously, but to date has not been brought to an industrially useful scale. PICASCO sets out to scale this final barrier.", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["780765"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["UNIVERSITEIT LEIDEN", "UNIVERSITEIT LEIDEN"], "EU_Contribution": ["EUR 1 999 761"], "Project_Title": ["Food citizens? Collective food procurement in European cities: solidarity and diversity, skills and scale"], "Total_Cost": ["EUR 1 999 761"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["FOOD CITIZENS"], "Technology_Description": "Considerable attention goes to \u2018smart\u2019 urban food procurement, with little notice of the cultural diversity within Europe. For a growing urban population (80% by 2050), food is a mediator of relations within social networks, not only a commodity or nutrient. Eaters are not just consumers but social actors whose meaning-making depend on faith, gender, age, income, or kinship. How we procure and share food is thus central to cultural understandings of citizenship: the project studies in-depth nine cases of collective food procurement across three European cities, asking if collective food procurement networks indicate emerging forms of \u2018food citizenship\u2019, or if they concomitantly co-produce hegemonic notions of participation and belonging \u2013 and either way, how.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["724151"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSIDAD DE OVIEDO", "UNIVERSIDAD DE OVIEDO"], "EU_Contribution": ["EUR 2 456 250"], "Project_Title": ["Deconstructing Ageing: from molecular mechanisms to intervention strategies"], "Total_Cost": ["EUR 2 456 250"], "Country": ["Spain", "Spain"], "Project_ACR": ["DeAge"], "Technology_Description": "Over many years, our research group has explored the complex relationship between cancer and ageing. As part of this work, we have generated mouse models of protease deficiency which are protected from cancer but exhibit accelerated ageing. Further studies with these mice have allowed us to unveil novel mechanisms of both normal and pathological ageing, to discover two new human progeroid syndromes, and to develop therapies for the Hutchinson-Gilford progeria syndrome, now in clinical trials. We have also integrated data from many laboratories to first define The hallmarks of ageing and the current possibilities for Metabolic control of longevity. Now, we propose to leverage our extensive experience in this field to further explore the relative relevance of cell-intrinsic and -extrinsic mechanisms of ageing. Our central hypothesis is that ageing derives from the combination of both systemic and cell-autonomous deficiencies which lead to the characteristic loss of fitness associated with this process. Accordingly, it is necessary to integrate multiple approaches to understand the mechanisms underlying ageing. This integrative and multidisciplinary project is organized around three major aims: 1) to characterize critical cell-intrinsic alterations which drive ageing; 2) to investigate ageing as a systemic process; and 3) to design intervention strategies aimed at expanding longevity. To fully address these objectives, we will use both hypothesis-driven and unbiased approaches, including next-generation sequencing, genome editing, and cell reprogramming. We will also perform in vivo experiments with mouse models of premature ageing, genomic and metagenomic studies with short- and long-lived organisms, and functional analyses with human samples from both progeria patients and centenarians. The information derived from this project will provide new insights into the molecular mechanisms of ageing and may lead to discover new opportunities to extend human healthspan.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["742067"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["IFOM FONDAZIONE ISTITUTO FIRC DI ONCOLOGIA MOLECOLARE", "IFOM FONDAZIONE ISTITUTO FIRC DI ONCOLOGIA MOLECOLARE"], "EU_Contribution": ["EUR 2 451 250"], "Project_Title": ["Inherited disfunctions of brain microcirculation"], "Total_Cost": ["EUR 2 451 250"], "Country": ["Italy", "Italy"], "Project_ACR": ["V-EPC"], "Technology_Description": "Cerebral cavernous malformations (CCM) is a disease characterized by focal capillary-venous cavernomas located in the central nervous system. These malformations are fragile and bleed leading to seizures, paralysis and cerebral hemorrhages. The familial form of CCM is due to loss of function mutations of anyone of three genes called Ccm1, Ccm 2 and Ccm 3. Open skull surgery is the only possible therapy since effective medical treatments are still missing. In mouse models of CCM and human patients\u2019 specimens, endothelial cells (ECs) lining the cavernomas co-express endothelial, mesenchymal and stem cell markers. These features combined to high cell proliferation are reminiscent of tumor initiating cells. In preliminary work, we isolated a rare population of highly proliferative ECs (V-EPC) intermingled with the normal vascular endothelium in vivo and co-expressing endothelial and stem cell markers. Our working hypothesis is that CCM originates from the clonal expansion of these V-EPCs that are more sensitive than mature endothelium to inactivation of Ccm genes. This possibility is supported by the observation that V-EPCs present a comparable gene expression profile and selective markers than the ECs lining CCM cavernomas. The project is divided in three related objectives: 1) To define the nature and functions of V-EPCs in normal vessels; 2) to test the capacity of V-EPCs to trigger the formation of CCM by undergoing clonal expansion in vivo; 3) to test whether targeting V-EPCs or inducing V-EPC maturation by pharmacological tools reduce or prevent the formation of CCM. If successful this work will introduce novel concepts in vascular biology such as: 1) the presence of resident V-EPCs that are differentially sensitive than mature endothelium to the same genetic mutation and angiogenic stimuli; 2) the identification of specific signaling pathways in V-EPC that explain their high proliferative potential; 3) the identification of V-EPC as therapeutic targets for CCM.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["742922"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["INSTITUTE OF EXPERIMENTAL MEDICINE - HUNGARIAN ACADEMY OF SCIENCES", "INSTITUTE OF EXPERIMENTAL MEDICINE - HUNGARIAN ACADEMY OF SCIENCES"], "EU_Contribution": ["EUR 1 597 575"], "Project_Title": ["Specificity of cortico-thalamic interactions and its role in frontal cortical functions"], "Total_Cost": ["EUR 1 597 575"], "Country": ["Hungary", "Hungary"], "Project_ACR": ["FRONTHAL"], "Technology_Description": "Frontal cortical areas are responsible for a wide range of executive and cognitive functions. Frontal cortices communicate with the thalamus via bidirectional pathways and these connections are indispensable for frontal cortical operations. Still, we have very little information about the specificity of connections, synaptic interactions and plasticity between frontal cortex and thalamus and the roles of these interactions in frontal cortical functions.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Hungary"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["742595"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITAT AUTONOMA DE BARCELONA", "UNIVERSITAT AUTONOMA DE BARCELONA"], "EU_Contribution": ["EUR 1 943 924"], "Project_Title": ["Behavioral-evolutionary analysis of climate policy: Bounded rationality, markets and social interactions"], "Total_Cost": ["EUR 1 943 924"], "Country": ["Spain", "Spain"], "Project_ACR": ["EVOCLIM"], "Technology_Description": "Distinct climate policies are studied with incomparable approaches involving unique criteria and impacts. I propose to unite core features of such approaches within a behavioral-evolutionary framework, offering three advantages: evaluate the effectiveness of very different climate policy instruments in a consistent and comparative way; examine policy mixes by considering interaction between instruments from a behavioral as well as systemic perspective; and simultaneously assessing policy impacts mediated by markets and social interactions.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["741087"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITY OF BRISTOL", "UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 2 294 320"], "Project_Title": ["Mechanisms of electroreception in bees and other terrestrial animals"], "Total_Cost": ["EUR 2 294 320"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["ElectroBee"], "Technology_Description": "Many animal species can detect the electric fields in their environment. Electroreception has mainly been studied in aquatic vertebrates; fish like sharks and rays, gymnotid and mormirid electric fish, the lamprey, the platypus, the coelacanth, and one mammalian species, a dolphin. We have discovered that bumblebees can detect and learn about the weak electric fields that arise when they approach a flower. This is the first example of electroreception in a non-conductive medium, aerial electroreception (AE). Recently, we showed that AE can be achieved through the electro-mechanical coupling of mechanosensory hairs to the weak electric field surrounding the animal. This is much like the hair-raising sensation humans used to experience by browsing an arm near to a cathodic television set. Yet, humans cannot sense the weak electric fields surrounding a flower, so this potentially informative physical quantity had escaped scientific attention. To date, little is known about AE, its sensory ecology and evolution.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["743093"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM", "UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Mapping the retrotransposon-mediated layer of neuronal gene regulation in the human genome"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["PRIMATE-TE-IMPACT"], "Technology_Description": "Throughout evolution, the human genome has been attacked by retrotransposons, parasitic DNA elements that spread through our genome by a copy-paste activity. I previously showed that SVA elements, the youngest class of retrotransposons in our genome, harbour a strong gene-regulatory potential which is normally repressed by KRAB zinc finger protein ZNF91 (Jacobs et al., 2014, Nature). However, for reasons unknown, repression of retrotransposons is much less efficient in the human brain, resulting in activation of the enhancer potential of SVA elements spread throughout the human genome. The importance of these SVA insertions for the evolution of human neuronal gene-regulatory networks, and how many genes have come to depend on SVA's regulatory influence, remains elusive. In this research program, I will use \u2018cortical organoids\u2019; three-dimensional brain tissues derived from human and primate stem cells, to investigate how recent SVA insertions have impacted human neuronal gene expression. Furthermore, I will investigate how changes of the epigenetic landscape in neurons affect the activity of retrotransposons in our genome and the influence they have on nearby neuronal genes. Finally, I will explore the possibility that loss of epigenetic silencing of retrotransposons is responsible for dysregulation of genes associated with neurological diseases. Preliminary findings suggest a potential role for retrotransposons in susceptibility loci for Alzheimer's and Parkinson's disease. Finding further support for this in the current research program, will form the basis of a novel concept which explains how changes in the epigenetic landscape can uncover a dormant genetic predisposition to disease.", "To": ["2022-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["716035"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN", "JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN"], "EU_Contribution": ["EUR 2 500 000"], "Project_Title": ["Dissecting and targeting ubiquitin networks in the course of bacterial infections"], "Total_Cost": ["EUR 2 500 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["Ub-BAC"], "Technology_Description": "Ubiquitination represents one of the most versatile post-translational modifications in eukaryotes and is involved in regulation of numerous cellular processes. Despite prokaryotes lacking this system, facultative intracellular bacteria like Salmonella, Shigella and Legionella have evolved multiple strategies to manipulate the host ubiquitin (Ub) system to their own benefit. This proposal is focussed on gaining a fundamental understanding of the Ub system in the course of bacterial infections. We will employ advanced quantitative proteomics to perform a global analysis of the dynamic changes in the ubiquitinome and phosphoproteome of epithelial cells and macrophages upon infection with Salmonella, Shigella and Legionella. The comprehensive datasets will constitute an invaluable resource freely available to the scientific community. We expect to identify novel pathways triggered by selected bacterial ligases and will characterise their contribution to pathogenicity and virulence, as well as their suitability for being targeted in a therapeutic setting. Both medicinal chemistry and structural biology approaches will be exploited to identify inhibitors for NEL-type bacterial ligases. Hypothesis-driven projects within the work program focus on (i) a novel chemical modification of Ub controlling Legionella infections and (ii) the observation that Ub chains on Salmonella can form nanoscale clusters that recruit and activate multiple signalling pathways within the host cell. Super-resolution microscopy and single-molecule imaging will be used to visualise and dissect these Ub-triggered complexes.", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["742720"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITY OF GLASGOW", "UNIVERSITY OF GLASGOW", "THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 3 005 817,75"], "Project_Title": ["Game-changing Precision Medicine for Curing All Myeloproliferative Neoplasms"], "Total_Cost": ["EUR 3 005 817,75"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom"], "Project_ACR": ["ChAMPioN"], "Technology_Description": "Despite decades of research, developing ways to overcome drug resistance in cancer is the most challenging bottleneck for curative therapies. This is because, in some forms of cancer, the cancer stem cells from which the diseases arise are constantly evolving, particularly under the selective pressures of drug therapies, in order to survive. The events leading to drug resistance can occur within one or more individual cancer stem cell(s) \u2013 and the features of each of these cells need to be studied in detail in order to develop drugs or drug combinations that can eradicate all of them. The BCR-ABL+ and BCR-ABL- myeloproliferative neoplasms (MPN) are a group of proliferative blood diseases that can be considered both exemplars of precision medicine and of the drug resistance bottleneck. While significant advances in the management of MPN have been made using life-long and expensive tyrosine kinase inhibitors (TKI), patients are rarely cured of their disease. This is because TKI fail to eradicate the leukaemia stem cells (LSC) from which MPN arise and which persist in patients on treatment, often leading to pervasive drug resistance, loss of response to therapy and progression to fatal forms of acute leukaemia. My goal is to change the way we study the LSC that persist in MPN patients as a means of delivering more effective precision medicine in MPN that is a \u201cgame-changer\u201d leading to therapy-free remission (TFR) and cure. Here, I will apply an innovative strategy, ChAMPioN, to study the response of the MPN LSC to TKI in innovative pre-clinical laboratory models and directly in patients with MPN - up to the resolution of individual LSC. This work will reveal, for the first time, the molecular and clonal evolution of LSC during TKI therapies, thus enabling the development of more accurate predictions of TKI efficacy and resistance and rational approaches for curative drug therapies.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["742349"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["POLITECNICO DI MILANO", "POLITECNICO DI MILANO"], "EU_Contribution": ["EUR 2 351 544"], "Project_Title": ["An Integrated Heart Model for the simulation of the cardiac function"], "Total_Cost": ["EUR 2 351 544"], "Country": ["Italy", "Italy"], "Project_ACR": ["iHEART"], "Technology_Description": "The goal of this project is to construct, mathematically analyze, numerically approximate, computationally solve, and validate on clinically relevant cases a mathematically-based integrated heart model (IHM) for the human cardiac function. The IHM comprises several core cardiac models \u2013 electrophysiology, solid and fluid mechanics, microscopic cellular force generation, and valve dynamics \u2013 which are then coupled and finally embedded into the systemic and pulmonary blood circulations. It is a multiscale system of Partial Differential Equations (PDEs) and Ordinary Differential Equations (ODEs) featuring multiphysics interactions among the core models.", "To": ["2022-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["740132"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITY OF BRISTOL", "UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 2 495 578"], "Project_Title": ["Generalization in Mind and Machine"], "Total_Cost": ["EUR 2 495 578"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["M and M"], "Technology_Description": "Is the human mind a symbolic computational device? This issue was at the core Chomsky\u2019s critique of Skinner in the 1960s, and motivated the debates regarding Parallel Distributed Processing models developed in the 1980s. The recent successes of \u201cdeep\u201d networks make this issue topical for psychology and neuroscience, and it raises the question of whether symbols are needed for artificial intelligence more generally.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["741134"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN", "JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN"], "EU_Contribution": ["EUR 2 497 140"], "Project_Title": ["Acetogenic bacteria: from basic physiology via gene regulation to application in industrial biotechnology"], "Total_Cost": ["EUR 2 497 140"], "Country": ["Germany", "Germany"], "Project_ACR": ["ACETOGENS"], "Technology_Description": "Demand for biofuels and other biologically derived commodities is growing worldwide as efforts increase to reduce reliance on fossil fuels and to limit climate change. Most commercial approaches rely on fermentations of organic matter with its inherent problems in producing CO2 and being in conflict with the food supply of humans. These problems are avoided if CO2 can be used as feedstock. Autotrophic organisms can fix CO2 by producing chemicals that are used as building blocks for the synthesis of cellular components (Biomass). Acetate-forming bacteria (acetogens) do neither require light nor oxygen for this and they can be used in bioreactors to reduce CO2 with hydrogen gas, carbon monoxide or an organic substrate. Gas fermentation using these bacteria has already been realized on an industrial level in two pre-commercial 100,000 gal/yr demonstration facilities to produce fuel ethanol from abundant waste gas resources (by LanzaTech). Acetogens can metabolise a wide variety of substrates that could be used for the production of biocommodities. However, their broad use to produce biofuels and platform chemicals from substrates other than gases or together with gases is hampered by our very limited knowledge about their metabolism and ability to use different substrates simultaneously. Nearly nothing is known about regulatory processes involved in substrate utilization or product formation but this is an absolute requirement for metabolic engineering approaches. The aim of this project is to provide this basic knowledge about metabolic routes in the acetogenic model strain Acetobacterium woodii and their regulation. We will unravel the function of \u201corganelles\u201d found in this bacterium and explore their potential as bio-nanoreactors for the production of biocommodities and pave the road for the industrial use of A. woodii in energy (hydrogen) storage. Thus, this project creates cutting-edge opportunities for the development of biosustainable technologies in Europe.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["741791"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["THE UNIVERSITY OF EDINBURGH", "THE UNIVERSITY OF EDINBURGH", "KING'S COLLEGE LONDON", "PUBLIC HEALTH FOUNDATION OF INDIA"], "EU_Contribution": ["EUR 1 479 558"], "Project_Title": ["Investigating the Design and Use of Diagnostic Devices in Global Health"], "Total_Cost": ["EUR 1 479 558"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom", "India"], "Project_ACR": ["DiaDev"], "Technology_Description": "Many people living in resource-poor settings have never had access to the laboratory facilities or technical expertise that are needed to diagnose diseases. With the development and deployment of a new generation of affordable, easy-to-use, and portable diagnostic devices that are designed for places with no laboratory infrastructure, the global landscape of diagnosis is dramatically changing. Can portable diagnostic devices strengthen health systems in resource-poor settings? DiaDev is the first study to comprehensively address this question through comparison across multiple devices, sites of production, and contexts of use. Diagnostic technologies are often championed as universal solutions to health equity and access. This ethnographic study investigates the extent to which how diagnostic devices work and what they can achieve depends on the locally specific relationships through which they are designed and used. Five ethnographic case studies from the USA, India and Sierra Leone examine the partnerships between donors, governments, humanitarian organisations and users that characterise current models of technological innovation and implementation in global health, the processes by which diagnostic devices are integrated with health infrastructures in target settings, and the practices of knowledge production and use they entail. The ultimate aim is to generate new insight into (i) changing relationships of power between governments, donors, and business in global health, and (ii) the ways in which diagnostic devices are transforming health systems in resource-poor settings. It will produce a new context-specific and comparative framework for exploring the opportunities and challenges involved in the design and use of diagnostic devices. Through innovative collaborative methods it will also develop a set of \u2018health system strengthening tools\u2019 that will enable stakeholders to improve the design and use of these devices in dialogue with the project findings.", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2017-05-01"], "Project_ID": ["715450"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["UNIVERSITY OF BRISTOL", "UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 2 499 238"], "Project_Title": ["Synthetic Cellularity via Protocell Design and Chemical Construction"], "Total_Cost": ["EUR 2 499 238"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["PCELLS"], "Technology_Description": "We propose to undertake an ambitious 5-year multidisciplinary programme that seeks to pioneer and establish a fundamentally new paradigm in protolife research that is based on novel conceptual and experimental advances in the design and construction of rudimentary forms of synthetic cell-like micro-ensembles (protocells). Our approach is positioned at the interface between materials chemistry, soft matter science and synthetic biology, and will address the following aspects of protocell design and construction: (i) functional complexity in protocell phenotypes, (ii) protocell self-structuring and metamorphosis, (iii) multi-compartmentalization and protocell endosymbiosis, and (iv) collective behavior in protocell communities. We will initiate unprecedented increases in the complexity of individual protocells by developing new types of structural architectures with advanced functions including photosynthetic protocells and motile proteinosomes, and develop innovative strategies for the chemical secretion of spatially extended extra-protocellular hydrogel matrices and induction of protocell metamorphosis. We will develop a modular micro-engineering approach to protocell multi-compartmentalization with the aim of generating coordinated enzyme- and gene-activated endosymbiotic interactions, and pioneer the experimental study of collective behaviour in communities of synthetic protocells. Our overall aim is to pioneer a modern approach to synthetic cellularity that advances the chemical and physical basis of protocell structure and function, and spearheads the development of future technologies based on autonomously functioning chemical micro-compartments with applications in bioinspired micro-storage and delivery, micro-reactor technologies, cytomimetic engineering, and the development of integrated constructs for diverse procedures in synthetic biology.", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["740235"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITY OF HULL", "UNIVERSITY OF HULL"], "EU_Contribution": ["EUR 2 581 155"], "Project_Title": ["Morphodynamic Stickiness: the influence of physical and biological cohesion in sedimentary systems"], "Total_Cost": ["EUR 2 581 155"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["GEOSTICK"], "Technology_Description": "Our coasts, estuaries, & low-land river environments are some of the most sensitive systems to sea-level rise & environmental change. In order to manage these systems, & adapt to future changes, we desperately need to be able to predict how they will alter under various scenarios. However, our models for these environments are not yet robust enough to predict, with confidence, very far into the future. Moreover, we also need to improve how we use our understanding of modern environments in reconstructing paleo-environments, where significant assumptions have been made in the way in which relationships derived from the modern have been applied to ancient rocks.", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["725955"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM", "UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["An Empirical Foundation for Understanding Positive Emotions"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["PEP"], "Technology_Description": "Positive emotions are of great importance for our physical and mental health and for our social relationships. However, scientific knowledge of positive emotions is lacking, with research to date being both fractionated and scarce. The Positive Emotions Project (PEP) takes on the challenge of formulating a foundational, empirically-based framework of positive emotions. This is accomplished by a set of studies combining methodologies that examine both subjective and objective elements of 17 positive emotions, including gratitude, awe, amusement, compassion, and relief. Central to the investigation is the integration of cross-cultural and developmental approaches, in order to differentiate between consistent patterns and idiosyncratic features. Project 1 will use experience sampling to map out the experience of positive emotions across ten dramatically different cultures, examining subjective elements of emotions, such as antecedent events and psychological states. Project 2 will comprehensively establish which nonverbal facial and vocal signals are associated with different positive emotions across cultures and ages. Project 3 will provide an integrated multi-level account of positive emotions, considering similarities and differences across emotions, taking into account cross-cultural and developmental patterning of subjective and objective features. The empirical and theoretical results of PEP will result in new, innovative paradigms, and substantial, freely available datasets that will help to redress the current dearth of data and approaches for understanding positive emotions. It will also provide the basis for a much-needed scientific, multifaceted account of positive emotion. Such a model will benefit scientists across many disciplines, including affective computing, behavioural economics, and psychiatry, whose work builds on psychological models of emotions.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["714977"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["UNIVERSITY OF BRISTOL", "UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 1 778 516"], "Project_Title": ["Log Correlations and Random Matrices"], "Total_Cost": ["EUR 1 778 516"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["LogCorRM"], "Technology_Description": "Random Matrix Theory has been of central importance in Mathematical Physics for over 50 years. It has deep connections with many other areas of Mathematics and a remarkably wide range of applications. In 2012, a new avenue of research was initiated linking Random Matrix Theory to the highly active area of Probability Theory concerned with the extreme values of logarithmically correlated Gaussian fields, such as the branching random walk and the two-dimensional Gaussian Free Field. This connects the extreme value statistics of the characteristic polynomials of random matrices asymptotically to those of the Gaussian fields in question, allowing some important and long-standing open questions to be addressed for the first time. It has led to a flurry of activity and significant progress towards proving some of the main conjectures. A remarkable discovery has been that the characteristic polynomials of random matrices exhibit, asymptotically, a hierarchical branching/tree structure like that of the branching random walk. However, many of the most important questions remain open. My aim is to attack some of these problems using ideas and techniques that have so far not been applied to them: I believe it is possible to compute some important statistical quantities relating to the extreme values of characteristic polynomials exactly, for the first time, by establishing connections with integrable systems, representation theory, and enumerative combinatorics. Such connections have not previously been explored. I anticipate that this will have a significant impact on an area that is currently in a rapid phase of development and that it will settle some of the principal unresolved conjectures. I further believe that ideas exploiting the hierarchical branching structure may have new and unexpected implications for areas connected with Random Matrix Theory, including, in particular, Number Theory, and I plan to explore these too.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["740900"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITAET LEIPZIG", "UNIVERSITAET LEIPZIG"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Quantitative understanding of target recognition on DNA based on directional zipping processes"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["ZIPgeting"], "Technology_Description": "In the recent years a number of protein systems have been identified that recognize long (tens of base pairs) DNA sequences and allow flexible programmability of their target specificity. This promoted an enormous range of applications in genome engineering and synthetic biology. This project aims to decipher the mechanisms by which these proteins recognize their DNA targets in order to develop quantitative models/predictors for target recognition and to avoid off-target effects.", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["724863"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["AGENZIA NAZIONALE PER LE NUOVE TECNOLOGIE, L'ENERGIA E LO SVILUPPO ECONOMICO SOSTENIBILE", "INSTITUTO NACIONAL DE SAUDE DR. RICARDO JORGE", "INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU BIORESURSE ALIMENTARE", "FUNDACION CIDETEC", "UNIVERSITE DE PAU ET DES PAYS DE L'ADOUR", "ARISTOTELIO PANEPISTIMIO THESSALONIKIS", "CESKA ZEMEDELSKA UNIVERZITA V PRAZE", "SZEGEDI TUDOMANYEGYETEM", "Finnish Food Safety Authority Evira", "RIJKSINSTITUUT VOOR VOLKSGEZONDHEID EN MILIEU", "TECHNISCHE UNIVERSITAET MUENCHEN", "INSTITUT JOZEF STEFAN", "J.Z.U. INSTITUT ZA JAVNO ZDRAVJE NA REPUBLIKA MAKEDONIJA SKOPJE", "INSTITUT SCIENTIFIQUE DE SANTE PUBLIQUE", "TURKIYE BILIMSEL VE TEKNOLOJIK ARASTIRMA KURUMU", "FUNDATIA DAS - PENTRU O MOLDOVA BAZATA PE CUNOASTERE", "PREMOTEC GMBH"], "EU_Contribution": ["EUR 1 959 537,75"], "Project_Title": ["Progressing towards the construction of METROFOOD-RI"], "Total_Cost": ["EUR 1 959 538,25"], "Country": ["Italy", "Portugal", "Romania", "Spain", "France", "Greece", "Czech Republic", "Hungary", "Finland", "Netherlands", "Germany", "Slovenia", "Former Yugoslav Republic of Macedonia", "Belgium", "Turkey", "Moldova", "Switzerland"], "Project_ACR": ["PRO-METROFOOD"], "Technology_Description": "The general objective of PRO-METROFOOD is to bring the emerging METROFOOD-RI ESFRI project to the level of maturity required for entering in the active project list, strengthening the Consortium and planning the future phases. The specific objectives have been set up in close relationship with the \u201cESFRI SWG & IG Recommendation\u201d. 4 specific objectives have been identified: OBJ1 \u2013 design strategies on the medium and long terms; OBJ2 \u2013 provide the organizational framework of METROFOOD-RI; OBJ3 \u2013 demonstrate the capability of METROFOOD-RI to supply scientific services and prepare the chart of services; OBJ4 \u2013 establish plans to coherently integrate METROFOOD-RI into the European landscape, realising coordination with EU and National initiatives and positioning at a global level. The strategic Plan will be tailored to the Pan European Infrastructure current and envisaged capabilities, market opportunities and business needs. It will be developed by involving funding agencies, relevant authorities supporting METROFOOD-RI and other stakeholders. A management conceptual model will be developed and the framework will be designed under operational, strategic and institutional aspects. Management procedures suitable for the different phases will set up, so to cover short and long-term goals. A Quality Documentation System (QDS) will be developed and a data management plan (DMP) will be defined. In order to demonstrate the capability of PRO-METROFOOD to supply services and to test its inter-operability, pilot services will be performed. In strict accordance with the METROFOOD-RI strategies, plans to coherently integrate METROFOOD-RI into the European landscape will be developed. A Communication plan and education and training programmes will be developed for the different phases of METROFOOD-RI realization (earl, preparatory, implementation and operational phases). For each phase the main coordinator, the target group and the main training subject areas will be specified.", "To": ["2017-12-31, closed project"], "Meta": [""], "Topic_s": ["INFRADEV-02-2016 - Preparatory Phase and support to early phase of ESFRI projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["739568"], "Call_for_Proposal": ["H2020-INFRADEV-2016-2"]}, -{"Partners": ["FUNDACION IMDEA NANOCIENCIA", "SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI DI TRIESTE", "SERVICIO DE SALUD DE CASTILLA LA MANCHA", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "Mfd-diagnostics GmbH", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 3 752 057,50"], "Project_Title": ["Towards an active bypass for neural reconnection"], "Total_Cost": ["EUR 3 752 057,50"], "Country": ["Spain", "Italy", "Spain", "France", "Germany", "Spain"], "Project_ACR": ["ByAxon"], "Technology_Description": "ByAxon is devoted to the development of a new generation of sensors and electrodes based on nanotechnology materials for neural interfacing. We aim to design and build a prototype of an active implant that could work directly at the spinal cord (SC) level. This implant will be primary focused on restoring the transmission of electrical signals in the injured SC, acting as an active local bypass, something not possible with current technology. Further applications might include deep brain stimulation or retinal implants, among others.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-01-2016-2017 - FET-Open research and innovation actions"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations"], "From": ["2017-01-01"], "Project_ID": ["737116"], "Call_for_Proposal": ["H2020-FETOPEN-1-2016-2017"]}, -{"Partners": ["UNIVERSITY OF BRISTOL", "UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 1 946 995"], "Project_Title": ["Sound and Early Assessment of Leakage for Embedded Software"], "Total_Cost": ["EUR 1 946 995"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["SEAL"], "Technology_Description": "Side channel attacks use, alongside information such as plaintexts or ciphertexts, leakage about the (secret) key-dependent intermediate state(s), and deliver a `key ranking' as a result. Kocher's attacks [15] [16] showed that for many practical implementations, observing a few encryptions made complete key recovery possible in practice. The academic research into combating these attacks so far has largely focused on approaches and tools to equip specialised cryptographic engineers with access to a specialist lab and tools. ", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["725042"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITY OF BRISTOL", "UNIVERSITY COLLEGE LONDON", "STICHTING KATHOLIEKE UNIVERSITEIT", "UNIVERSITY OF LIMERICK"], "EU_Contribution": ["EUR 2 886 323,75"], "Project_Title": ["Magnetic Control of Polymorphism in Pharmaceutical Compounds"], "Total_Cost": ["EUR 2 886 323,75"], "Country": ["United Kingdom", "United Kingdom", "Netherlands", "Ireland"], "Project_ACR": ["MagnaPharm"], "Technology_Description": "This H2020-FETOPEN-2016-2017 proposal initiates a major international effort to direct polymorphism in pharmaceutical compounds through crystallizing in high magnetic fields. The ability to direct polymorphism would have a transformative effect on almost all pharmaceutical compounds, and hence on society.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-01-2016-2017 - FET-Open research and innovation actions"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["736899"], "Call_for_Proposal": ["H2020-FETOPEN-1-2016-2017"]}, -{"Partners": ["LINKOPINGS UNIVERSITET", "LINKOPINGS UNIVERSITET"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Predicting future methane fluxes from Northern lakes"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["METLAKE"], "Technology_Description": "The new global temperature goal calls for reliable quantification of present and future greenhouse gas (GHG) emissions, including climate feedbacks. Non-CO2 GHGs, with methane (CH4) being the most important, represent a large but highly uncertain component in global GHG budget. Lakes are among the largest natural sources of CH4 but our understanding of lake CH4 fluxes is rudimentary. Lake emissions are not yet routinely monitored, and coherent, spatially representative, long-term datasets are rare which hamper accurate flux estimates and predictions.", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["725546"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["OBSERVATOIRE DE PARIS", "ISTITUTO NAZIONALE DI RICERCA METROLOGICA", "PHYSIKALISCH-TECHNISCHE BUNDESANSTALT", "NPL MANAGEMENT LIMITED", "GROUPEMENT D INTERET PUBLIC POUR LERESEAU NATIONAL DE TELECOMMUNICATIONS POUR LA TECHNOLOGIE L ENSEIGNEMENT ET LA RECHERCHE", "CESNET ZAJMOVE SDRUZENI PRAVNICKYCH OSOB", "INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK", "UNIVERSITE PARIS 13", "MUQUANS", "Menlo Systems GmbH", "PIKTIME SYSTEMS SP ZOO", "USTAV PRISTROJOVE TECHNIKY AVCR VVI", "SEVEN SOLUTIONS SL", "OPTOKON AS", "AKADEMIA GORNICZO-HUTNICZA IM. STANISLAWA STASZICA W KRAKOWIE", "UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 1 994 645"], "Project_Title": ["CLOck NETwork Services: Strategy and innovation for clock services over optical-fibre networks"], "Total_Cost": ["EUR 1 994 646,25"], "Country": ["France", "Italy", "Germany", "United Kingdom", "France", "Czech Republic", "Poland", "France", "France", "Germany", "Poland", "Czech Republic", "Spain", "Czech Republic", "Poland", "United Kingdom"], "Project_ACR": ["CLONETS"], "Technology_Description": "\"A scientific and technological paradigm change is taking place, concerning the way that very high performance time and frequency reference signals are distributed, moving from radio signal broadcasting to signal transport over optical fibre networks. The latter technology demonstrates performance improvements by orders of magnitude, over distances up to continental scale. Research infrastructures are developing several related technologies, adapted to specific projects and applications. ", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["INFRAINNOV-02-2016 - Support to Technological Infrastructures"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Paolo Antonio Mastroeni", "Tel.: +39-011-3919541", "Fax: +39-011-346384", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["731107"], "Call_for_Proposal": ["H2020-INFRAINNOV-2016-1"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM", "UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 1 457 063"], "Project_Title": ["Cognitive Semantics and Quantities"], "Total_Cost": ["EUR 1 457 063"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["CoSaQ"], "Technology_Description": "At the heart of the multi-faceted enterprise of formal semantics lies a simple yet powerful conception of meaning based on truth-conditions: one understands a sentence if one knows under which circumstances the sentence is true. This notion has been extremely fruitful resulting in a wealth of practical applications. But to what extent can it also account for the human linguistic behavior? The past decade has seen the increasing interaction between cognitive science and formal semantics, and the emergence of the new field of experimental semantics. One of its main challenges is the traditional normative take on meaning, which makes semantic theories hard to compare with experimental data. The aim of this project is to advance experimental semantics by building cognitive semantics, that is semantics founded on cognitive representations instead of normative logical abstractions.", "To": ["2022-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-02-01"], "Project_ID": ["716230"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["DIGITAL RESEARCH INFRASTRUCTURE FOR THE ARTS AND HUMANITIES", "GEORG-AUGUST-UNIVERSITAT GOTTINGENSTIFTUNG OFFENTLICHEN RECHTS", "UNIVERSITEIT GENT", "UNIWERSYTET WARSZAWSKI", "UNIVERSIDADE NOVA DE LISBOA", "FACULDADE DE CIENCIAS SOCIAIS E HUMANAS DA UNIVERSIDADE NOVA DE LISBOA", "CENTAR ZA DIGITALNE HUMANISTICKE NAUKE", "GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER", "INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE", "KING'S COLLEGE LONDON", "UNIVERSITY OF GLASGOW", "KNIHOVNA AV CR V. V. I.", "HELSINGIN YLIOPISTO", "SWISS INSTITUTE OF BIOINFORMATICS", "UNIVERSIDAD NACIONAL DE EDUCACION A DISTANCIA", "UNIVERSITY OF HAIFA"], "EU_Contribution": ["EUR 2 717 320"], "Project_Title": ["DARIAH ERIC Sustainability Refined"], "Total_Cost": ["EUR 2 717 320"], "Country": ["France", "Germany", "Belgium", "Poland", "Portugal", "Portugal", "Serbia", "Germany", "France", "United Kingdom", "United Kingdom", "Czech Republic", "Finland", "Switzerland", "Spain", "Israel"], "Project_ACR": ["DESIR"], "Technology_Description": "Europe has a long and rich tradition as a centre for the arts and humanities. However, the digital transformation poses challenges to the arts and humanities research landscape all over the world. Responding to these challenges the Digital Research Infrastructure for Arts and Humanities (DARIAH) was launched as a pan-European network and research infrastructure. After expansion and consolidation, which involved DARIAH\u2019s inscription on the ESFRI roadmap, DARIAH became a European Research Infrastructure Consortium (ERIC) in August 2014.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["INFRADEV-03-2016-2017 - Individual support to ESFRI and other world-class research infrastructures"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["731081"], "Call_for_Proposal": ["H2020-INFRADEV-2016-1"]}, -{"Partners": ["UNIVERSITE DE LIMOGES", "BANGOR UNIVERSITY", "IHP GMBH - INNOVATIONS FOR HIGH PERFORMANCE MICROELECTRONICS/LEIBNIZ-INSTITUT FUER INNOVATIVE MIKROELEKTRONIK", "AGENZIA NAZIONALE PER LE NUOVE TECNOLOGIE, L'ENERGIA E LO SVILUPPO ECONOMICO SOSTENIBILE", "UNIVERSITA DEGLI STUDI DI PADOVA", "CREO MEDICAL LIMITED"], "EU_Contribution": ["EUR 3 978 517,50"], "Project_Title": ["Semiconductor-based Ultrawideband Micromanipulation of CAncer STEm Cells"], "Total_Cost": ["EUR 3 978 517,50"], "Country": ["France", "United Kingdom", "Germany", "Italy", "Italy", "United Kingdom"], "Project_ACR": ["SUMCASTEC"], "Technology_Description": "SUMCASTEC explores radically new approach for cancer stem cells (CSCs) real time isolation (i.e. within minutes vs current 40 days) and neutralization. A novel micro-optofluidic lab-on-chip (LOC) platform will be developed through a joint and iterative effort by biologists, clinicians and engineers. For the first time, a single LOC will be capable of delivering ultra-wide broadband radiation to compare cell spectral signatures, image subcellular features, and hence modulate CSCs microenvironment conditions with unprecedented space and time resolution. It will be driven to isolate CSCs from heterogeneous differentiated and stem cell populations, and force CSCs differentiation, ultimately inducing sensitivity to anticancer treatments. Extensive in vitro and in vivo testing along with biophysical modelling will validate the approach and establish the proof-of-principle within the project life-time, while laying the groundwork for further development of future electrosurgical tools that will be capable CSCs neutralization in tissue. ", "To": ["2020-06-30, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-01-2016-2017 - FET-Open research and innovation actions"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["737164"], "Call_for_Proposal": ["H2020-FETOPEN-1-2016-2017"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM", "UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 1 499 766"], "Project_Title": ["Towards a neural and cognitive architecture of consciousness"], "Total_Cost": ["EUR 1 499 766"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["CONSCIOUSNESS"], "Technology_Description": "For decades the cognitive neuroscience community has expended significant effort identifying system-level neural correlates of human consciousness, broad neural signatures that distinguish conscious from unconscious processes at the level of whole brain regions. Meanwhile, within the field of neurobiology, rapid progress has been made in understanding the neurotransmitter systems underlying basic sensory processes (e.g. in mice, monkeys). This research has, however, been performed in relative isolation from studies of human consciousness, and clear opportunities to link the two levels of description remain largely unexplored. Here I will establish this link by combining state-of-the-art neuroimaging techniques with pharmacological interventions. ", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["715605"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["PROTOBIOS OU", "TARTU ULIKOOL", "SIHTASUTUS TARTU ULIKOOLI KLIINIKUM", "TALLINNA TEHNIKAULIKOOL", "KING'S COLLEGE LONDON", "HELSINGIN YLIOPISTO", "HELSINGIN JA UUDENMAAN SAIRAANHOITOPIIRIN KUNTAYHTYM\u00c4", "ELVESYS SAS", "OU QURETEC"], "EU_Contribution": ["EUR 1 305 000"], "Project_Title": ["Towards Early Molecular Diagnostics of Schizophrenia"], "Total_Cost": ["EUR 1 305 000"], "Country": ["Estonia", "Estonia", "Estonia", "Estonia", "United Kingdom", "Finland", "Finland", "France", "Estonia"], "Project_ACR": ["SZ_TEST"], "Technology_Description": "Schizophrenia (SZ) is a severe mental disorder affecting more than 0.7% of the adult population. One of the most disabling and emotionally devastating illnesses known to man, SZ is also associated with considerable socioeconomic burden. In general, the chronic nature and the high degree of patient disability make SZ the fourth leading cause of disease burden across the globe with the management costs making up ~3% of the total healthcare budget in the Western countries. The situation is even direr in some regions, including northern Sweden and Finland, where relative prevalence of SZ exceeds two to three times corresponding national or regional averages. Poorly understood aetiology and limited diagnostic arsenal make it difficult to detect and treat SZ in a timely and efficient manner. This underscores a critical need for better understanding of the mechanisms underlying SZ and development of new diagnostic possibilities allowing its early detection, ideally prior to the onset of psychosis. The SZ_TEST will address these challenges by coordinating efforts with complementary areas of expertise in genetics, epigenetics, neurodevelopment, molecular psychiatry, clinical immunology and biotech R&D. The overarching hypothesis underlying our work is that genetic vulnerabilities, neurodevelopmental defects, exposure to pathogens, immune system status and specific lifestyle choices may compound the risk of SZ and that a systematic multivariate analysis of these factors should result in substantially improved diagnostic tools. SZ_TEST will work towards the development of molecular diagnostics tools for early detection of SZ, by using relevant cohorts of human subjects, unique animal and cell models, and combining unbiased high-throughput omic screens with knowledge-based candidate marker analyses. SZ_TEST training network is expected to have a major impact on improving the quality of life and reducing the health care costs in Europe and worldwide.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Estonia"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["734791"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM", "UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 1 300 775"], "Project_Title": ["Non AdS holography and generalized geometric structures"], "Total_Cost": ["EUR 1 300 775"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["GenGeoHol"], "Technology_Description": "Holography is by now a fundamental tool in the understanding of both strongly coupled conformal field theories (CFTs) and quantum theories of gravity. While holography in Anti de Sitter (AdS) space-times is rather well understood, we currently lack a basic picture of what it means in non-AdS space-times. Considering non-AdS space-times is an essential and urgent next step in the study of quantum gravity as we seem to live in a universe with a positive cosmological constant that is approaching de Sitter (dS) in the far future. Also, the near-horizon geometries of black holes are typically described by more exotic geometries that need to be understood on their own right.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["715656"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["UNIVERSITY OF HULL", "MUNTERS EUROPE AB", "INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK", "DATA CENTRE ALLIANCE LIMITED", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "NPS HUMBER LIMITED", "HISENSE GERMANY GMBH", "APPLIED INDUSTRIAL TECHNOLOGIES LTD"], "EU_Contribution": ["EUR 1 156 500"], "Project_Title": ["Low Energy Dew Point Cooling for Computing Data Centres"], "Total_Cost": ["EUR 1 845 000"], "Country": ["United Kingdom", "Sweden", "Poland", "United Kingdom", "France", "United Kingdom", "Germany", "Greece"], "Project_ACR": ["DEW-COOL-4-CDC"], "Technology_Description": "Cooling systems for Computing & Data Centres consume 30% to 40% of energy delivered into the centre spaces, while electricity use in CDCs represents 1.3% of the world total energy consumption. The traditional vapour compression cooling systems for CDCs are neither energy efficient nor environmentally friendly. Several alternative cooling systems, e.g., adsorption/absorption, ejector, and evaporative types, have certain level of energy saving potential but exhibit some inherent problems that have restricted their wide applications in CDCs. This RISE programme aims to form an international and inter-sectoral network of organisations working on a joint research and innovation programme dedicated to develop the design theory, computerised tool and technology prototypes for a novel CDC dew point cooling system. Such a system, comprising a few critical and highly innovative components (i.e., dew point air cooler, adsorbent sorption/regeneration cycle, micro-channels-loop-heat-pipe (MCLHP) based CDC heat recovery system, paraffin/expanded-graphite based heat storage/exchanger, and internet-based intelligent monitoring and control system), is expected to achieve 60% to 90% of electrical energy saving and have a comparable initial price to traditional CDC air conditioning systems, thus removing the above outstanding problems remaining with existing CDC cooling systems. Within the programme, the participants will exchange skills and knowledge that will allow them to progress towards the key target set for the CDC dew point cooling system, and strengthen collaborative research among different countries and sectors. The advances in the novel CDC dew point cooling system will have potential market opportunities for non-academic participants in the programme, and have significant benefits to European society and economy. The staff members who participate in the programme will develop new skills, be exposed to new research environments and have their career perspectives widened.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["734340"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA", "UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Evaluation of commercial potential of a low-cost kit based on DNA-nanoswitches for the single-step measurement of diagnostic antibodies"], "Total_Cost": ["EUR 150 000"], "Country": ["Italy", "Italy"], "Project_ACR": ["AB-SWITCH"], "Technology_Description": "\"Antibodies are among the most widely monitored class of diagnostic biomarkers. Immunoassays market now covers about 1/3 of the global market of in-vitro diagnostics (about $50 billion). However, current methods for the detection of diagnostic antibodies are either qualitative or require cumbersome, resource-intensive laboratory procedures that need hours to provide clinicians with diagnostic information. A new method for fast and low-cost detection of antibodies will have a strong economic impact in the market of in-vitro diagnostics and Immunoassays.", "To": ["2018-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-02-01"], "Project_ID": ["727313"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA", "UNIVERSITAT POLITECNICA DE CATALUNYA", "LEIBNIZ-INSTITUT FUER NEUE MATERIALIEN GEMEINNUETZIGE GMBH", "KING'S COLLEGE LONDON", "UNIVERSITAIR MEDISCH CENTRUM UTRECHT", "MIND THE BYTE SL", "NOVIOCELL BV"], "EU_Contribution": ["EUR 7 134 928,75"], "Project_Title": ["Mechanical control of biological function"], "Total_Cost": ["EUR 7 134 928,75"], "Country": ["Spain", "Spain", "Germany", "United Kingdom", "Netherlands", "Spain", "Netherlands"], "Project_ACR": ["MECHANO-CONTROL"], "Technology_Description": "Mechanical forces transmitted through specific molecular bonds drive biological function, and their understanding and control hold an uncharted potential in oncology, regenerative medicine and biomaterial design. However, this potential has not been realised, because it requires developing and integrating disparate technologies to measure and manipulate mechanical and adhesive properties from the nanometre to the metre scale. We propose to address this challenge by building an interdisciplinary research community with the aim of understanding and controlling cellular mechanics from the molecular to the organism scale. At the nanometric molecular level, we will develop cellular microenvironments enabled by peptidomimetics of cell-cell and cell-matrix ligands, with defined mechanical and adhesive properties that we will dynamically control in time and space trough photo-activation. The properties under force of the molecular bonds involved will be characterized using single-molecule atomic force microscopy and magnetic tweezers. At the cell-to-organ scale, we will combine controlled microenvironments and interfering strategies with the development of techniques to measure and control mechanical forces and adhesion in cells and tissues, and to evaluate their biological response. At the organism scale, we will establish how cellular mechanics can be controlled, by targeting specific adhesive interactions, to impair or abrogate breast tumour progression in a mouse model. At all stages and scales of the project, we will integrate experimental data with multi-scale computational modelling to establish the rules driving biological response to mechanics and adhesion. With this approach, we aim to develop specific therapeutic approaches beyond the current paradigm in breast cancer treatment. Beyond breast cancer, the general principles targeted by our technology will have high applicability in oncology, regenerative medicine and biomaterials.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["FETPROACT-01-2016 - FET Proactive: emerging themes and communities"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["731957"], "Call_for_Proposal": ["FETPROACT-2016"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM", "UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 1 465 097"], "Project_Title": ["Fast and efficient sponge engines drive and modulate the food web of reef ecosystems"], "Total_Cost": ["EUR 1 465 097"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["SPONGE ENGINE"], "Technology_Description": "Coral reefs are iconic examples of biological hotspots, highly appreciated because of their ecosystem services. Yet, they are threatened by human impact and climate change, highlighting the need to develop tools and strategies to curtail changes in these ecosystems. Remarkably, ever since Darwin\u2019s descriptions of coral reefs, it has been a mystery how one of Earth\u2019s most productive and diverse ecosystems thrives in oligotrophic seas, as an oasis in a marine desert. My team recently discovered the \u2018sponge loop\u2019 pathway (Science, De Goeij et al 2013) that efficiently retains and transfers energy and nutrients on the reef. We recognized sponges as potential (and so far neglected) key ecosystem drivers, and accumulated evidence on sponge loops in other ecosystems, such as deep-sea coral reefs. As a result, current reef food web models, lacking sponge-driven resource cycling, are incomplete and need to be redeveloped. However, mechanisms that determine the capacity of sponge 'engines', how they are fuelled, and drive communities are unknown. ", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["715513"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["STICHTING VU", "KING'S COLLEGE LONDON", "GOETEBORGS UNIVERSITET", "UNIVERSITY OF BRISTOL", "ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM", "KAROLINSKA INSTITUTET", "UNIVERSITEIT TWENTE", "UNIVERSITA DEGLI STUDI DI CAGLIARI", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "JANSSEN-CILAG AKTIEBOLAG"], "EU_Contribution": ["EUR 3 163 687,92"], "Project_Title": ["Childhood and Adolescence Psychopathology: unravelling the complex etiology by a large Interdisciplinary Collaboration in Europe"], "Total_Cost": ["EUR 3 163 687,92"], "Country": ["Netherlands", "United Kingdom", "Sweden", "United Kingdom", "Netherlands", "Sweden", "Netherlands", "Italy", "United Kingdom", "Sweden"], "Project_ACR": ["CAPICE"], "Technology_Description": "In the Roadmap for Mental Health and Wellbeing Research in Europe (ROAMER), top-priority is research into child and adolescent mental health symptoms. CAPICE (Childhood and Adolescence Psychopathology: unravelling the complex etiology by a large Interdisciplinary Collaboration in Europe) will address this priority. ", "To": ["2021-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-02-01"], "Project_ID": ["721567"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM", "UNIVERSITY OF LEICESTER", "UNIVERSITAETSMEDIZIN GOETTINGEN - GEORG-AUGUST-UNIVERSITAET GOETTINGEN - STIFTUNG OEFFENTLICHEN RECHTS", "INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE", "ECOLE NORMALE SUPERIEURE", "UNIVERSIDAD DE SALAMANCA", "KING'S COLLEGE LONDON", "UNIVERSITAETSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITAET MAINZ"], "EU_Contribution": ["EUR 2 584 755,72"], "Project_Title": ["Liaison in Scientific Training for European auditory Neuroscience"], "Total_Cost": ["EUR 2 584 755,72"], "Country": ["Netherlands", "United Kingdom", "Germany", "France", "France", "Spain", "United Kingdom", "Germany"], "Project_ACR": ["LISTEN"], "Technology_Description": "This ITN will train 10 ESRs to meet the urgent need for translation of Auditory Neuroscience into commercial and pharmaceutical products to treat hearing disorders including tinnitus. Tinnitus is the debilitating perception of imaginary sound that is often associated with hearing loss. This Liaison in Scientific Training for European auditory Neuroscience (LISTEN) is a consortium of top hearing scientists in industry and academia, who specialize in hearing mechanisms and translation to commercial applications, enabling broad career opportunities for our ESRs. The multidisciplinary training environment includes leading labs and companies from 7 EU states, specialized in research, drug and instrumental development. Hearing is vulnerable to noise trauma, medication and aging, and in the future hearing loss will be one of the top ten disease burdens for Europe. Europe must rapidly exploit academic knowledge to invest in treatments for hearing disorders including drug development. Young scientists entering this field must acquire a broad and detailed background in neuroscience, acoustics, biophysics and signal processing, and employ genetic, molecular, pharmacology, anatomy and imaging methods. No single European institute can encompass this, but together, our LISTEN network will enable young scientists and entrepreneurs to unravel hearing mechanisms and design the next-generation of treatments. Work Package 1 (WP1) focuses on neural coding of sounds from the cochlea to neocortex, including auditory processing for localizing sounds and complex cognitive tasks in both normal hearing and following hearing loss. WP2 will identify molecular and genetic mechanisms of the hyperexcitability underlying tinnitus, exploit new techniques for monitoring tinnitus and develop new drug therapies. Integration of the WPs will enable new insights into disease mechanisms and WP3 will provide the ESRs with an essential multidisciplinary background for their research and successful careers.", "To": ["2020-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-12-01"], "Project_ID": ["722098"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI SALERNO", "TECHNISCHE UNIVERSITEIT EINDHOVEN", "FUNDACION TECNALIA RESEARCH & INNOVATION", "ICI CALDAIE SPA", "KT - KINETICS TECHNOLOGY SPA", "L AIR LIQUIDE SA"], "EU_Contribution": ["EUR 688 500"], "Project_Title": ["PROcess intensification through the development of innovative MEmbranes and CAtalysts"], "Total_Cost": ["EUR 688 500"], "Country": ["Italy", "Netherlands", "Spain", "Italy", "Italy", "France"], "Project_ACR": ["PROMECA"], "Technology_Description": "PROMECA strategic objective is to substantially contribute to the increase of knowledge, skills, and competitiveness in the European research area and industry, through the design and deployment of a thorough plan of research and secondment of researchers between top-level EU academia and industrial partners, contributing to the main European Policies on innovation. In line with the MSCA-RISE general objectives, the project will:", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["734561"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM", "UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 1 926 634"], "Project_Title": ["The Impact of Massive Binaries Through Cosmic Time"], "Total_Cost": ["EUR 1 926 634"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["BinCosmos"], "Technology_Description": "Massive stars play many key roles in Astrophysics. As COSMIC ENGINES they transformed the pristine Universe left after the Big Bang into our modern Universe. We use massive stars, their explosions and products as COSMIC PROBES to study the conditions in the distant Universe and the extreme physics inaccessible at earth. Models of massive stars are thus widely applied. A central common assumption is that massive stars are non-rotating single objects, in stark contrast with new data. Recent studies show that majority (70% according to our data) will experience severe interaction with a companion (Sana, de Mink et al. Science 2012). ", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["714063"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI TERAMO", "UNIVERSITA DEGLI STUDI DI CAGLIARI", "UNIVERSIDAD DE BURGOS", "AVANTEA srl", "BIOTALENTUM TUDASFEJLESZTO KFT", "IMAGENE", "BIOBANKS AND BIOMOLECULAR RESOURCES RESEARCH INFRASTRUCTURE CONSORTIUM (BBMRI-ERIC)", "UNIVERSITA DEGLI STUDI DI MODENA E REGGIO EMILIA"], "EU_Contribution": ["EUR 765 000"], "Project_Title": ["Setting an interdisciplinary/sectorial/international research network to explore dry storage as an alternative strategy for cells/germplasm biobanking"], "Total_Cost": ["EUR 841 500"], "Country": ["Italy", "Italy", "Spain", "Italy", "Hungary", "France", "Austria", "Italy"], "Project_ACR": ["DRYNET"], "Technology_Description": "The number of biobanks for diagnostic/clinical/biodiversity preservation purposes is increasing exponentially, representing an economic burden for the EU. Cryopreservation (Liquid Nitrogen LN) is the only cells/gametes long-term repository method. LN storage is expensive though, requires dedicated facilities, is hazardous, carries pathogens and has high carbon footprint. DRYNET objective is to set an inter-sectorial/multidisciplinary/international network between EU academic (5), SME (3), the EU pan-Biobank, and international partners (Japan/Thailand), with the aim of sharing knowhow & expertise to lay down the theoretical and early empirical basis for the dry storage of cells/germplasm. DRYNET merges the partner\u2019s expertise, theoretical/ biophysical/ mathematical modelling, cellular/ molecular/ insect biology, embryology, mechanical engineering into a coherent approach towards dry storage of cells/germplasm. International/inter-sectorial secondments, with meeting/workshop/summer school will be primary tools to implement our strategy for biobanking. Outreaching activities will guarantee public awareness of the project. DRYNET\u2019s relies on water subtraction to induce a reversible block of metabolism, a survival strategy available in nature (anhydrobiosis). The work plan foresees the exploitation of natural xero-protectants (Late Embryogenesis Abundant proteins), loaded/expressed in gametes/cells, before drying. The best drying approaches, supported by theoretical/biophysical/math modelling, will be implemented by SMEs/academy partners. DRYNET will bring a simplification of currents practices, with cost and carbon footprint reduction, for the maintenance/shipping of biobanks. DRYNET will generate young scientists with transferable skills, ensuring career prospect in academia/industry. DRYNET strengthens the international/sectorial network between different disciplines, ensures long-term sustainability of the project, and boosts European competitiveness in biobanking.", "To": ["2021-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2017-03-01"], "Project_ID": ["734434"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["UNIVERSITY OF BRISTOL", "UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 149 918"], "Project_Title": ["Quaternary Amino Acids on Scale for Medicine and Agroscience"], "Total_Cost": ["EUR 149 918"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["QUATERMAIN"], "Technology_Description": "Enantiopure quaternary amino acids, carrying two carbon-based substituents at the \u03b1 carbon, are one of the most important groups of modified \u03b1 amino acids, of great commercial value in the development of new pharmaceuticals and agrochemicals. Certain of these quaternary amino acids are readily available by stereoselective \u03b1 alkylation of available amino acids, but not those functionalized by the addition of \u03b1-aryl groups. In this project, we propose to develop an industrially scalable, practical method for the synthesis of \u03b1-arylated quaternary amino acids in enantiomerically pure form by streamlining, optimization and scale-up of a reaction we discovered while working on the synthesis of quaternary amino acids as conformational controllers within an ERC-funded Advanced Grant. The method is operationally simple and employs only inexpensive commodity chemicals as precursors. It uses no chiral auxiliary or catalyst, and exploits both structure and stereochemistry of the starting amino acid to make the quaternary amino acids in enantiomerically pure form. It avoid the use of transition metals, freeing the method from the potential problems associated with their toxicity, cost and volatility of supply. The nearest competitive methods are either limited in scope to electron-deficient aryl rings, or they employ toxic and expensive transition metal catalysts. Interest in the method has been garnered from the fine chemical, pharmaceutical and agrochemical industry, but further work on scale-up and practical issues are needed for the technology to become industry-ready.", "To": ["2018-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-11-01"], "Project_ID": ["727296"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI MILANO", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSITY OF NEWCASTLE UPON TYNE", "UNIVERSITE CATHOLIQUE DE LOUVAIN", "UNIVERSITEIT VAN AMSTERDAM", "THE UNIVERSITY OF BIRMINGHAM", "UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II.", "AICURIS ANTI-INFECTIVE CURES GMBH", "ANTIBIOTX APS", "BIOVERSYS AG", "NAICONS SRL"], "EU_Contribution": ["EUR 3 931 378,20"], "Project_Title": ["An integrated mulTidisciplinary appRoach towards a new generAtIon of aNtibiotics: Targeting function and cross-talk of bacterial Envelope proTein machineries"], "Total_Cost": ["EUR 3 931 378,20"], "Country": ["Italy", "France", "United Kingdom", "Belgium", "Netherlands", "United Kingdom", "Italy", "Germany", "Denmark", "Switzerland", "Italy"], "Project_ACR": ["Train2Target"], "Technology_Description": "Train2Target is a multidisciplinary European Training Network built to address the challenge of the discovery of alternative antimicrobials. Innovative strategies to deliver a next generation of drugs are urgently needed. The alarming threats and spread of multi-drug resistant bacteria is currently leaving clinicians with very limited options to combat infections especially those from Gram-negative pathogens. ", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["721484"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["STICHTING ASTRON, NETHERLANDS INSTITUTE FOR RADIO ASTRONOMY", "THE UNIVERSITY OF MANCHESTER", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "ISTITUTO NAZIONALE DI ASTROFISICA", "CHALMERS TEKNISKA HOEGSKOLA AB", "GEANT LIMITED", "STICHTING EGI", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "FORSCHUNGSZENTRUM JULICH GMBH", "SKA ORGANISATION", "SCIENCE AND TECHNOLOGY FACILITIES COUNCIL", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "INSTITUTO DE TELECOMUNICACOES", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "ETHNIKO DIKTYO EREVNAS TECHNOLOGIAS AE", "STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN", "JOINT INSTITUTE FOR VERY LONG BASELINE INTERFEROMETRY AS A EUROPEAN RESEARCH INFRASTRUCTURE CONSORTIUM (JIV-ERIC)", "STICHTING INTERNATIONAL LOFAR TELESCOPE", "UPPSALA UNIVERSITET", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "UNIVERSITE DE GENEVE", "COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION", "AARNET PTY LTD", "THE RESEARCH TRUST OF VICTORIA UNIVERSITY OF WELLINGTON", "COUNCIL FOR SCIENTIFIC AND INDUSTRIAL RESEARCH", "UNIVERSITY OF CAPE TOWN", "NATIONAL RESEARCH FOUNDATION", "RESEARCH DATA ALLIANCE FOUNDATION"], "EU_Contribution": ["EUR 2 999 995"], "Project_Title": ["Advanced European Network of E-infrastructuresfor Astronomy with the SKA"], "Total_Cost": ["EUR 2 999 995"], "Country": ["Netherlands", "United Kingdom", "United Kingdom", "Italy", "Sweden", "United Kingdom", "Netherlands", "Germany", "Germany", "United Kingdom", "United Kingdom", "Spain", "Portugal", "France", "Greece", "Netherlands", "Netherlands", "Netherlands", "Sweden", "Switzerland", "Switzerland", "Australia", "Australia", "New Zealand", "South Africa", "South Africa", "South Africa", "United Kingdom"], "Project_ACR": ["AENEAS"], "Technology_Description": "The objective of the AENEAS project is to develop a concept and design for a distributed, federated European Science Data Centre (ESDC) to support the astronomical community in achieving the scientific goals of the Square Kilometre Array (SKA). The scientific potential of the SKA radio telescope is unprecedented and represents one of the highest priorities for the international scientific community. By the same token, the large scale, rate, and complexity of data the SKA will generate, present challenges in data management, computing, and networking that are similarly world-leading. SKA Regional Centres (SRC) like the ESDC will be a vital resource to enable the community to take advantage of the scientific potential of the SKA. Within the tiered SKA operational model, the SRCs will provide essential functionality which is not currently provisioned within the directly operated SKA facilities. AENEAS brings together all the European member states currently part of the SKA project as well as potential future EU SKA national partners, the SKA Organisation itself, and a larger group of international partners including the two host countries Australia and South Africa.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["INFRASUPP-03-2016 - Support to policies and international cooperation for e-infrastructures"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Netherlands"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Other", "Other", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Other", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations"], "From": ["2017-01-01"], "Project_ID": ["731016"], "Call_for_Proposal": ["H2020-INFRASUPP-2016-1"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI PAVIA", "ECOLE ROYALE MILITAIRE - KONINKLIJKE MILITAIRE SCHOOL", "UNIVERSIDAD DE EXTREMADURA"], "EU_Contribution": ["EUR 270 000"], "Project_Title": ["TOOLS FOR MAPPING HUMAN EXPOSURE TO RISKY ENVIRONMENTAL CONDITIONS BY MEANS OF GROUND AND EARTH OBSERVATION DATA"], "Total_Cost": ["EUR 324 000"], "Country": ["Italy", "Belgium", "Spain"], "Project_ACR": ["EOXPOSURE"], "Technology_Description": "The goal of the EOxposure project is to build tools to quantify the exposure of population and economic assets to multiple risks using novel information layers from current and future Earth Observation (EO) missions, as well as the growing sensor web on the ground.", "To": ["2021-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-03-01"], "Project_ID": ["734541"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["UNIVERSITY OF BRISTOL", "UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 1 809 752"], "Project_Title": ["High-Pressure High-Temperature Superconductivity"], "Total_Cost": ["EUR 1 809 752"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["HPSuper"], "Technology_Description": "Superconductors promote electrical currents without loss and are exploited for applications like magnets in medical imaging. Further applications like large scale usage in electrical power generation and transmission, however, are limited by the need to cool materials below a critical temperature Tc. Thus, novel superconductors with higher Tc are highly desirable.", "To": ["2022-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-02-01"], "Project_ID": ["715262"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["UNIVERSITETET I STAVANGER", "UNIVERSITY OF LINCOLN", "UNIVERSITEIT TWENTE", "UNIVERSITAT AUTONOMA DE BARCELONA", "LINKOPINGS UNIVERSITET", "UNIVERSIDADE DE AVEIRO", "AALBORG UNIVERSITET", "COMUNIDADE INTERMUNICIPAL DA REGIAO DE AVEIRO", "REGIO TWENTE"], "EU_Contribution": ["EUR 3 709 815,84"], "Project_Title": ["The Role of Universities in Innovation and Regional Development"], "Total_Cost": ["EUR 3 709 815,84"], "Country": ["Norway", "United Kingdom", "Netherlands", "Spain", "Sweden", "Portugal", "Denmark", "Portugal", "Netherlands"], "Project_ACR": ["RUNIN"], "Technology_Description": "The Role of Universities in Innovation and Regional Development (RUNIN) is a European Training Network for Early-Stage Researchers (ESRs) in the field of science and innovation studies. The aim of the network is to train researchers on how universities contribute to innovation and economic growth in their regions through research seeking to examine how universities fulfill their third mission in relation to regional industry and explore the range of university engagement with regional firms and institutions. The project operationalises the main research question of how universities can contribute to innovation and regional development through four main themes: People and Networks, Policies and Interventions, Places and Territories, and Practices and Governance. The aim of the training programme is to equip the next generation of researchers with the skills required to work across employment sectors, collaborate with a wide range of stakeholders and find the practical relevance of their specialist knowledge, in the process creating new knowledge on universities\u2019 role in innovation and regional development. There is an increased focus on the instrumentalist position of universities as important drivers of regional development, and the aim of the training programme is therefore to equip a new generation of researchers who can work within this field in the academic world or as specialist policy makers at the regional, national or European level. The programme will capitalise on host institutions\u2019 infrastructure, including supervision, methods training and quality assurance review systems. In addition, it will offer a comprehensive programme of learning through individual research projects, secondments, and eight targeted training events aimed at developing both research-specific and transferable skills.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2016-09-01"], "Project_ID": ["722295"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM", "STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS", "JUSTUS-LIEBIG-UNIVERSITAET GIESSEN", "UNIVERSITY OF BRISTOL", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "MEDICAL RESEARCH COUNCIL", "FUTURESYNTHESIS SP ZOO", "ELVESYS SAS"], "EU_Contribution": ["EUR 3 097 183,68"], "Project_Title": ["Regulated Assembly of Molecular Machines for DNA REPAIR: a Molecular Analysis training Network"], "Total_Cost": ["EUR 3 097 183,68"], "Country": ["Netherlands", "Netherlands", "Germany", "United Kingdom", "France", "United Kingdom", "Poland", "France"], "Project_ACR": ["DNAREPAIRMAN"], "Technology_Description": "The European Training Network DNAREPAIRMAN aims to train a new generation of innovative young scientists in cutting edge biophysical research methodology to address central questions in biology concerning the mode of action of critical molecular machines with relevance for human health. The Network consists of a highly collaborative consortium consisting of 12 participants coming from academia, industry, and the creative sector. Participating laboratories in the Network are part of established research schools within renowned research organizations and Universities, with supervisors who are experts within their respective research field, publish regularly in high-impact journals and have received EURYI and ERC awards. This environment of excellence offers a multidisciplinary PhD program to 12 young researchers (ESRs), through training in the analysis of basic chemical and physical principles that underlie the correct timing and localization of events during DNA repair. In addition training will center around method development using methodology, equipment, software and experience provided first-hand by four small technology-driven companies. Individual research projects as well as personal training plans will be implemented for each ESR, incorporating a local training program, multiple rotations within partner laboratories, exposure to the non-academic sector and Network meetings. ESRs will follow scientific workshops, courses in transferable skills, career development and entrepreneurship, and will disseminate and communicate their projects to a diverse audience in close collaboration with the creative sector. DNAREPAIRMAN will result in a new generation of mature and innovative European scientists with a thorough understanding of fundamental quantitative principles underlying biology, with experience in technique development, and affinity for the academic as well as the non-academic research setting, providing a broad and promising career perspective.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["722433"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN", "KAROLINSKA INSTITUTET", "STOCKHOLMS LANS LANDSTING", "UNIVERSITEIT GENT", "UNIVERSITA DEGLI STUDI DI PADOVA", "THE UNIVERSITY OF SHEFFIELD", "SP PROCESS DEVELOPMENT AB", "UNIVERSITAET BERN", "TURUN YLIOPISTO", "MEDIMMUNE LIMITED", "ASTRAZENECA AB"], "EU_Contribution": ["EUR 3 971 347,92"], "Project_Title": ["Molecular Tools for Nucleic Acid Manipulation for Biological Intervention"], "Total_Cost": ["EUR 3 971 347,92"], "Country": ["United Kingdom", "Germany", "Sweden", "Sweden", "Belgium", "Italy", "United Kingdom", "Sweden", "Switzerland", "Finland", "United Kingdom", "Sweden"], "Project_ACR": ["MMBio"], "Technology_Description": "MMbio will bridge the classically separate disciplines of Chemistry and Biology by assembling leading experts from academia and non-academic partners (industry, technology transfer & science communication) to bring about systems designed to interfere therapeutically with gene expression in living cells. Expertise in nucleic acid synthesis, its molecular recognition and chemical reactivity is combined with drug delivery, cellular biology and experimental medicine. This project represents a concerted effort to make use of a basic and quantitative understanding of chemical interactions to develop and deliver oligonucleotide molecules of utility for therapy. Our chemical biology approach to this field is ambitious in its breadth and represents a unqiues opportunity to educate young scientists across sectorial and disciplinary barriers. Training will naturally encompass a wide range of skills, requiring a joint effort of chemists and biologists to introduce young researchers in a structured way to and array of research methodologies that no single research grouping could provide. The incorporation of early-stage and later stag ebiotechnology enterprises ensures that commercialisation of methodologies as well as the drug development process is covered in this ITN. We hope that MMBio will train scientists able to understand both the biological problem and the chemistry that holds the possible solution and develop original experimental approaches to stimulate European academic and commercial success in this area.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["721613"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["OSLO UNIVERSITETSSYKEHUS HF", "UNIVERSIDAD DE CORDOBA", "NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU", "UNIVERSITE PARIS 13", "CASCINATION AG", "UNIVERSITAET BERN", "INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE", "STIFTELSEN SINTEF", "TECHNISCHE UNIVERSITEIT DELFT"], "EU_Contribution": ["EUR 4 041 920,04"], "Project_Title": ["High Performance Soft-tissue Navigation"], "Total_Cost": ["EUR 4 041 920,04"], "Country": ["Norway", "Spain", "Norway", "France", "Switzerland", "Switzerland", "France", "Norway", "Netherlands"], "Project_ACR": ["HiPerNav"], "Technology_Description": "Primary liver cancer, which consists predominantly of hepatocellular carcinoma (HCC), is the fifth most common cancer worldwide and the third most common cause of cancer mortality. A successful surgical resection of HCC requires complete removal of the tumour while sparing as much healthy tissue as possible. Due to technical and clinical difficulties relatively low percentage of patients are eligible for resection. There is an urgent need to increase the patient eligibility and improve the survival prognosis after liver interventions. HiPerNav will train early stage researchers (biomedical engineers and medical doctors) to become international leading in key areas of expertise through a novel coordinated plan of individual research projects addressing specific bottlenecks in soft tissue navigation for improved treatment of liver cancer. The multi-disciplinary dialogue and work between clinicians and biomedical engineers is crucial to address these bottlenecks. By providing researchers with knowledge and training within specific topics from minimally invasive treatment, biomedical engineering, research methodologies, innovation and entrepreneurship, the link between academic research and industry will be strengthened. This allows for easy transfer of promising results from the research projects to commercially exploitable solutions. The global image guided surgery devices market is promising; it was valued at USD 2.76 billion in 2013 and is projected to expand 6.4% from 2014 to 2022 to reach USD 4.80 billion in 2022. The market for soft-tissue navigation is still in its infancy, mainly due to challenges in achieved accuracy for targeting deformable and moving organs. By providing multi-disciplinary training, the researchers in this consortium of international leading research institutions, universities and industry will initiate true translational research from academic theoretical ideas to the clinical testing of prototype, developed solutions and tools.", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2016-11-01"], "Project_ID": ["722068"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "UNIVERSITA CA' FOSCARI VENEZIA", "CHALMERS TEKNISKA HOEGSKOLA AB", "UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6", "UNIVERSITE PARIS DIDEROT - PARIS 7", "VRIJE UNIVERSITEIT BRUSSEL", "UNIVERSITEIT VAN AMSTERDAM", "UNIVERSITAET LEIPZIG"], "EU_Contribution": ["EUR 5 817 276,25"], "Project_Title": ["Opinion Dynamics and Cultural Conflict in European Spaces"], "Total_Cost": ["EUR 5 817 276,25"], "Country": ["Germany", "Italy", "Sweden", "France", "France", "Belgium", "Netherlands", "Germany"], "Project_ACR": ["ODYCCEUS"], "Technology_Description": "Social media and the digitization of news and discussion fora are having far-reaching effects on the way individuals and communities communicate, organize, and express themselves. Can the information circulating on these platforms be tapped to better understand and analyze the enormous problems facing our contemporary society? Could this help us to better monitor the growing number of social crises due to cultural differences and diverging world-views? Would this facilitate early detection and perhaps even ways to resolve conflicts before they lead to violence? The Odycceus project answers all these questions affirmatively. It will develop the conceptual foundations, methodologies, and tools to translate this bold vision into reality and demonstrate its power in a large number of cases. ", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["FETPROACT-01-2016 - FET Proactive: emerging themes and communities"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["732942"], "Call_for_Proposal": ["FETPROACT-2016"]}, -{"Partners": ["KING'S COLLEGE LONDON", "KING'S COLLEGE LONDON"], "EU_Contribution": ["EUR 1 427 361"], "Project_Title": ["Particle-Surface Interactions in Near Field Optics: Spin-orbit Effects of Light and Optical/Casimir Forces"], "Total_Cost": ["EUR 1 427 361"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["PSINFONI"], "Technology_Description": "PSINFONI aims to open new avenues of research in ultrafast routing and polarization synthesis of light in nanophotonics, and in the manipulation, sorting, levitation and trapping of nanoparticles, molecules, or single atoms near novel nanomaterial surfaces. To this end, we will explore the fundamentals and applications of a range of novel nanophotonic phenomena: (i) spin-orbit interactions of light for polarization-controlled optical routing and polarization synthesis at the nanoscale; (ii) repulsive and switchable lateral optical forces on particles near engineered surfaces for optical manipulation and sorting; and (iii) Casimir repulsive and lateral forces for quantum levitation / frictionless nanomaterials. All these diverse phenomena can be studied under the single framework of particle-surface interactions in the near field, greatly diversifying the research outcomes from a single research effort. Knowledge of the full 3D electromagnetic fields in particle-surface systems will form the foundation from which to explore fundamental aspects and limitations of the above mentioned effects, opening new applications in information technologies and new nanomaterials. Proof of principle experimental demonstrations will be performed where possible.", "To": ["2022-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-03-01"], "Project_ID": ["714151"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["PSIQUADRO SOCIETA COOPERATIVA", "EUROPEAN GRAVITATIONAL OBSERVATORY", "ISTITUTO NAZIONALE DI FISICA NUCLEARE", "UNIVERSITA DEGLI STUDI DI PERUGIA", "UNIVERSITA POLITECNICA DELLE MARCHE", "UNIVERSITA DEGLI STUDI DI PALERMO", "OBSERVA"], "EU_Contribution": ["EUR 384 600"], "Project_Title": ["SHAring Researchers\u2019 Passion for Engagement and Responsibility"], "Total_Cost": ["EUR 512 743,75"], "Country": ["Italy", "Italy", "Italy", "Italy", "Italy", "Italy", "Italy"], "Project_ACR": ["SHARPER"], "Technology_Description": "Researchers love to engage with nature, society, with future and ultimately with all the complex challenges that will allow them to contribute to a better world. Researchers also love to engage with other people to make the quest they\u2019re involved in a collective endeavour. All this make researchers persons passionate for engagement who are developing a growing sense of responsibility related to their work and their role in society. In such a professional life researchers experience strong driving forces such as enthusiasm, emotions, combined with new knowledge and innovative discoveries. All these elements are summarized in the acronym SHARPER - Sharing Researchers\u2019 Passion for Engagement and Responsibility the name of the European Researchers\u2019 Night in the Centre and South of Italy that will take place on the 30th of September 2016 and on the 29th of September 2017 simultaneously in five cities: Perugia, L\u2019Aquila, Ancona and Palermo \u2013 the four capital cities of the regions Marche, Umbria, Abruzzo, Sicily and in Cascina the city hosting the European Gravitational Observatory one of the cutting edge European research facilities. This network of cities combined with their Research Institutions and with their social and cultural actors provides a team of excellence and reliability both in the fields of research and science communication at national and international level. The SHARPER project will create effective communication bridges between researchers and the cities and communities they live and act within, through: street labs, exhibitions, performances in city squares or activities that will take place in focal city venues, where citizens use to spend their everyday life. SHARPER 2016-2017 will geographically broaden the impact of the communication actions of European Researchers\u2019 Night in Italy massively engaging kids, young students, schools, associations and citizens at large actively involved by researchers since the planning phase of the activities.", "To": ["2017-11-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-NIGHT-2016 - European Researchers' Night"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Italy"], "Activity": ["Other", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2016-05-01"], "Project_ID": ["722981"], "Call_for_Proposal": ["H2020-MSCA-NIGHT-2016"]}, -{"Partners": ["GOETEBORGS UNIVERSITET", "UNIVERSITY COLLEGE LONDON", "UNIVERSITEIT VAN AMSTERDAM", "INSTITUTO UNIVERSITARIO DE LISBOA", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "UNIVERSITEIT HASSELT", "UNIVERSITEIT UTRECHT", "ISTITUTO PER I BENI ARTISTICI CULTURALI E NATURALI DELLA REGIONE EMILIA ROMAGNA"], "EU_Contribution": ["EUR 3 867 561"], "Project_Title": ["Critical Heritage Studies and the Future of Europe_Towards an integrated, interdisciplinary and transnational training model in cultural heritage research and management"], "Total_Cost": ["EUR 3 867 561"], "Country": ["Sweden", "United Kingdom", "Netherlands", "Portugal", "Spain", "Belgium", "Netherlands", "Italy"], "Project_ACR": ["CHEurope"], "Technology_Description": "CHEurope focuses on developing a new integrated theoretical and methodological framework to enhance the academic and professional training and open future job opportunities in cultural heritage preservation, management and promotion. Heritage has commonly been perceived through its contingent relationship to other areas, preventing it to be considered as a \u2018legitimate\u2019 scientific discipline. Moreover, research and practice in this field are still too often seen as separate dimensions. Thus, there is an increasing need to address these diverging trends in the expanding heritage industry with a critical approach that situates cultural heritage in its social, economic and political frameworks, as well as in professional practice. ", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2016-11-01"], "Project_ID": ["722416"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["UNIVERSITAET BIELEFELD", "UNIVERSITEIT VAN AMSTERDAM", "UNIVERSITE CATHOLIQUE DE LOUVAIN", "UNIVERSITE PARIS I PANTHEON-SORBONNE", "UNIVERSITA CA' FOSCARI VENEZIA", "UNIVERSITA CATTOLICA DEL SACRO CUORE", "UNIVERSITY OF SURREY"], "EU_Contribution": ["EUR 3 864 090,24"], "Project_Title": ["Expectations and Social Influence Dynamics in Economics"], "Total_Cost": ["EUR 3 864 090,24"], "Country": ["Germany", "Netherlands", "Belgium", "France", "Italy", "Italy", "United Kingdom"], "Project_ACR": ["ExSIDE"], "Technology_Description": "Expectations play a crucial role in determining the behaviour of many economic decision makers. The recent financial and economic crisis has highlighted the importance of expectation dynamics for economic development, the success of firm strategies and public policies. The Innovative Training Network ExSIDE aims at improving our understanding of the role of expectation formation and social influence for economic dynamics and for the optimal design of economic policy. ", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EJD - European Joint Doctorates"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["721846"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["INTEGRATED CARBON OBSERVATION SYSTEM EUROPEAN RESEARCH INFRASTRUCTURE CONSORTIUM", "UNIVERSITETET I BERGEN", "UNIVERSITA DEGLI STUDI DELLA TUSCIA", "UNIVERSITE DE VERSAILLES SAINT-QUENTIN-EN-YVELINES.", "RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG", "USTAV VYZKUMU GLOBALNI ZMENY AV CR VVI", "RIJKSUNIVERSITEIT GRONINGEN", "NATURAL ENVIRONMENT RESEARCH COUNCIL", "HELSINGIN YLIOPISTO", "LUNDS UNIVERSITET", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "UNIVERSITEIT ANTWERPEN", "NATIONAL INSTITUTE OF RESEARCH AND DEVELOPMENT FOR OPTOELECTRONICS", "ORSZAGOS METEOROLOGIAI SZOLGALAT", "UNIVERSIDAD DE LAS PALMAS DE GRAN CANARIA", "NATIONAL OBSERVATORY OF ATHENS", "UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN", "EESTI MAAULIKOOL", "Instituto Superior de Agronomia", "UNIVERSITY OF THE WITWATERSRAND JOHANNESBURG", "UNIWERSYTET PRZYRODNICZY W POZNANIU*", "DANMARKS TEKNISKE UNIVERSITET", "HELMHOLTZ ZENTRUM FUR OZEANFORSCHUNG KIEL", "UNIVERSITAET BREMEN", "JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN", "INSTITUT ROYAL D'AERONOMIE SPATIALEDE BELGIQUE", "DEUTSCHER WETTERDIENST", "LEIBNIZ-INSTITUT FUR OSTSEEFORSCHUNG WARNEMUNDE STIFTUNG"], "EU_Contribution": ["EUR 4 719 680"], "Project_Title": ["Readiness of ICOS for Necessities of integrated Global Observations"], "Total_Cost": ["EUR 4 719 680"], "Country": ["Finland", "Norway", "Italy", "France", "Germany", "Czech Republic", "Netherlands", "United Kingdom", "Finland", "Sweden", "Switzerland", "Belgium", "Romania", "Hungary", "Spain", "Greece", "Ireland", "Estonia", "Portugal", "South Africa", "Poland", "Denmark", "Germany", "Germany", "Germany", "Belgium", "Germany", "Germany"], "Project_ACR": ["RINGO"], "Technology_Description": "The proposed project \u201cReadiness of ICOS for Necessities of integrated Global Observations\u201d (RINGO) aims to further development of ICOS RI and ICOS ERIC and foster its sustainability. The challenges are to further develop the readiness of ICOS RI along five principal objectives: ", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["INFRADEV-03-2016-2017 - Individual support to ESFRI and other world-class research infrastructures"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Finland"], "Activity": ["Other", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations"], "From": ["2017-01-01"], "Project_ID": ["730944"], "Call_for_Proposal": ["H2020-INFRADEV-2016-1"]}, -{"Partners": ["LUNDS UNIVERSITET", "LUNDS UNIVERSITET"], "EU_Contribution": ["EUR 1 969 445"], "Project_Title": ["Pancreatic islet dysfunction and type 2 diabetes \u2013 beyond the genome"], "Total_Cost": ["EUR 1 969 445"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["PAINTBOX"], "Technology_Description": "The prevalence of type 2 diabetes (T2D) is rapidly increasing worldwide and despite great efforts to prevent and cure the disease, the increase persist. There is an urgent need to develop innovative and effective prevention and treatment strategies for T2D. ", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["725840"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET", "KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 2 176 250"], "Project_Title": ["The Ocular Glymphatic System"], "Total_Cost": ["EUR 2 176 250"], "Country": ["Denmark", "Denmark"], "Project_ACR": ["GlymphEye"], "Technology_Description": "The glymphatic system is a highly organized brain-wide mechanism by which fluid wastes are removed from the brain that was recently described by my team. The glymphatic system clears 65% of amyloid-beta from the normal adult brain. A rapidly evolving literature has shown that the major neurodegenerative diseases of the eye, macular degeneration and glaucoma, may also result from the toxicity of uncleared protein wastes, including amyloid-beta. Yet the eye, like the brain, has no traditional lymphatic vessels. In this application, I propose that two of the most significant causes of human visual loss, macular degeneration and glaucoma \u2013 previously thought of as both intractable and unrelated \u2013 are instead mechanistically allied disorders that not only share a common causal pathway, but may both be therapeutically modified by targeting dysregulation of the glymphatic pathway. As such, this proposal seeks to link the biology of a fundamentally new pathway for both metabolic substrate and waste transport in the adult brain, to diseases of the eye that have long been resistant to either understanding or treatment. ", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["742112"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITE CATHOLIQUE DE LOUVAIN"], "EU_Contribution": ["EUR 160 800"], "Project_Title": ["The top quark crucible: Standard Model and beyond the Standard Model physics in top quark precision studies"], "Total_Cost": ["EUR 160 800"], "Country": ["Belgium"], "Project_ACR": ["TQCRCBL"], "Technology_Description": "This proposal describes the exploration of properties of the top quark for the study of Standard Model physics and tests of physics beyond the Standard model. Research will be conducted starting from the data of 13 TeV run of the Large Hadron Collider with particular focus on the determination of the top quark mass and other observables that might be sensitive to subtle new physics, which hides in standard searches for new physics carried out at the Large Hadron Collider experiments, in particular searches that suffer from large systematic uncertainties in the sensitive regions of phase space.", "To": ["2019-08-31, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["702768"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE UNIVERSITY OF WARWICK"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Beyond the Secular: Narrativizing religious change in contemporary German novels"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["BeSec"], "Technology_Description": "The death of God and the disenchantment of the world are central to self-presentations of modernity. At the dawn of the third millennium, however, the worldwide growth of religious fundamentalisms as well as the pluralisation and individualization (but not the disappearance) of faith in the West suggest the need for a more nuanced understanding of the relation between secularity, modernity and religion. This is not only a matter for empirical research in Social, Political and Religious Studies. \u201cModernity,\u201d \u201csecularity\u201d and \u201creligion\u201d are, in important ways, interpretive categories shaped by cultural narratives through which individuals and societies understand their world. The project \u201cBeyond the Secular\u201d studies a defined corpus of such narratives: contemporary German-language novels which articulate non-secular and religious experiences and worldviews. Through an interdisciplinary methodology combining close reading and narratological analysis with contextual readings in religious sociology, theology, and political philosophy, the project seeks to determine the potential of literature for the perception and narrativization of religious change in late modern societies.", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["656000"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Anti-EGFR Monoclonal Antibody Conjugated Thermoresponsive Liposome for Triple Negative Breast Cancer Thermo-Chemotherapy"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["MULTIFUNSOME"], "Technology_Description": "In Europe, breast cancer is by far the most important cause of cancer death among women. In particular, triple negative breast cancer (TNBC) is an aggressive histological subtype with limited treatment options and associated with poorer prognosis than other breast cancer subtypes. MULTIFUNSOME proposes the use of an anti-Epidermal Growth Factor Receptor (EGFR) monoclonal antibody-conjugated thermoresponsive liposome to deliver simultaneously an anticancer drug and superparamagnetic iron oxide nanoparticles (SPIO) to TNBC cells for thermo-chemotherapy. We will investigate: 1) the effect of combining anti-EGFR targeting and magnetic hyperthermia (MH) on TNBC in such thermo-chemotherapy and 2) how chemical-physical properties of the SPIOs and liposomes influence the therapeutic activity of the formulation. By conjugating anti-EGFR monoclonal antibody to a liposomal delivery system for targeting, drug and SPIO internalization into EGFR overexpressing TNBC cells will be greatly enhanced. SPIO co-encapsulation in the drug nano-cargo will induce a thermal dose to the TNBC cells when an alternating magnetic field is applied. MH will make TNBC cells more sensitive to chemotherapy and trigger the release of drugs intracellularly by enhancing the lipid membrane permeability. As a result, the effectiveness of chemotherapy could be synergistically enhanced by the concurrent application of MH and chemotherapy. The core size of SPIO will serve as a design parameter that can be readily manipulated to maximize the heating efficient of the multicore SPIO so as to minimize the necessary iron oxide content and maximize the drug encapsulation efficiency. The fellowship program will include a comprehensive training which will help the fellow to develop a unique multidisciplinary expertise. Furthermore, the project will generate important knowledge, impacts and collaborations in the European Research Area and could potentially address the critical need for a more efficacious TNBC therapy.", "To": ["2019-08-31, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["700309"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Epigenetically Stable Cloned Plants: Increasing The Epigenetic and Phenotypic Diversity of Plants through Tissue-Specific Regeneration"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["Epi-Somaclone"], "Technology_Description": "Most of phenotypic variation comes from variation in DNA sequence. However, a number of studies have clearly shown that phenotype variation and diversity can also be the result of epigenetic changes. The major goal of this proposal is to develop a novel methodology for robust production of epigenetically stable plant variants, in order to increase epigenetic and phenotypic diversity. A key element in the project will be a recent breakthrough in the generation of clonal individuals from different tissue types using inducible overexpression of the embryonic regulatory protein RKD4. Preliminary work shows that plants regenerated from roots inherit many aspects of root specific methylation and gene expression patterns, even in the leaf tissue. Importantly, these features are stably transmitted across generations. For this project, I propose to: (1) evaluate physiological consequences of altered epigenomes in RKD4 regenerated plants; (2) compare (epi)genomic and phenotypic variation between plants regenerated using hormones and RKD4 overexpression; (3) compare epigenomic and phenotypic consequences in regenerants of different Arabidopsis thaliana accessions and close A. thaliana relatives Arabidopsis lyrata and Capsella rubella. The program, which will be carried out under supervision of Detlef Weigel, a world leader in plant genetics and genomics, will substantially contribute to increasing the toolkit for plant breeders to generate meaningful phenotypic diversity.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-10-01"], "Project_ID": ["751204"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["WEIZMANN INSTITUTE OF SCIENCE", "WEIZMANN INSTITUTE OF SCIENCE"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["SFICAM: Ultrafast Fiber-Based Single-Photon Camera for Advanced Microscopy"], "Total_Cost": ["EUR 150 000"], "Country": ["Israel", "Israel"], "Project_ACR": ["SFICAM"], "Technology_Description": "Light microscopy is critical to many fields, from biology and medicine to technology development and industry. One important breakthrough that enabled the development of super-resolution microscopy was the development of enhanced cameras capable of recording low light-level images with single-photon sensitivity. However such gain in spatial resolution is compromised by low temporal resolution, since these cameras work at video rate or somewhat faster, while many applications require to characterize dynamics which could be a million times faster. ", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["779971"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 200 194,80"], "Project_Title": ["Investigating Changes in Antarctic Marine Ecosystems using Environmental DNA"], "Total_Cost": ["EUR 200 194,80"], "Country": ["Denmark"], "Project_ACR": ["ICEDNA"], "Technology_Description": "The earth's climate is changing rapidly and nowhere more so than in polar regions. The Intergovernmental Panel on Climate Change has noted that polar marine ecosystems are especially vulnerable to climate change impacts, through the synergistic effects of both thermal climate changes and ocean acidification. How such impacts will transpire biologically and the flow-on effects from this are quite unclear, and there is broad acknowledgment of this scientifically and in terms of public policy. Polar ecosystems are extremely difficult to work in and gather field data from, so there is a strong need to appraise the efficacy of powerful new techniques for studying them. This project (ICEDNA) proposes to appraise and apply the nascent technique of environmental DNA (eDNA) analysis to elucidate how polar marine ecosystems respond to environmental impacts. ICEDNA leverages on recent manipulative and ecological field experiments in Antarctic nearshore ecosystems. These experiments focused on detection of fine scale human impacts from research stations and the biological impacts from ocean acidification. By marrying spatially and temporally nested eDNA data with traditional physical, chemical and biological data collection techniques, ICEDNA will yield a thorough understanding of the uses and limits of eDNA for marine (and polar) biodiversity and ecological monitoring, which is at the forefront of marine ecological research. These data will also yield unprecedented insight into (1) how polar marine communities respond to small scale human impacts and (2) how these communities respond to the large scale human impact of ocean acidification. ICEDNA combines the latest eDNA methods from Europe with the applicants extensive applied ecology experience, to produce a dynamic multidisciplinary researcher.", "To": ["2019-11-24, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-11-25"], "Project_ID": ["749851"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["STICHTING KATHOLIEKE UNIVERSITEIT"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["Tuning Emergent Phases in 2D Materials"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["EMERGE"], "Technology_Description": "The goal of EMERGE is to create new types of two-dimensional materials of the highest quality, and exploit new types of quantum phenomena that emerge in the lower dimensional limit. By combining ultra-high purity fabrication of 2D materials with a high level of control, with high precision spectroscopy, we aim at being able to tailor the phase of these materials with atomic precision. Since the discovery of graphene, there has been an ongoing search for new Dirac materials which exhibit exotic electronic behavior in the two-dimensional limit, in which the spin and electronic degrees of freedom can be manipulated. Toward this end, the family of transition metal dichalcogenides (TMDCs) is extremely promising, as this family of materials exhibits semiconducting behavior, novel spin transport, charge ordering, and superconductivity, when simply selecting the transition metal ion and the interface. However, the role of the environment and how this determines the quantum phases of these materials is still not well understood, and moreover there are still many of these materials which have not been realized. The objective here will be to fabricate and tune TMDCs at the 2D limit, to realize new types of TMDCs, in order to realize exotic phases of matter to unravel the role of the environment and material in creating and discovering new types of quantum phases of matter in these materials. Our goals will be accomplished by combining CVD fabrication of TMDC single layers in ultra-high vacuum, with in-situ characterization of these films with cutting edge spin-polarized scanning tunneling microscopy at ultra-low temperature and high magnetic fields, and angular resolved photoemission in order to fully understand the electronic properties of our materials.", "To": ["2019-08-03, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-04"], "Project_ID": ["751437"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["LUNDS UNIVERSITET", "LUNDS UNIVERSITET"], "EU_Contribution": ["EUR 1 875 000"], "Project_Title": ["Novel Approach to Systematically Characterize Exercise- and Nutrient- responsive genes in Type 2 diabetes and cardiovascular disease"], "Total_Cost": ["EUR 1 875 000"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["NASCENT"], "Technology_Description": "Proposal summary", "To": ["2022-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-02-01"], "Project_ID": ["681742"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["LUNDS UNIVERSITET", "LUNDS UNIVERSITET"], "EU_Contribution": ["EUR 1 999 412"], "Project_Title": ["Learning to See in a Dynamic World"], "Total_Cost": ["EUR 1 999 412"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["SEED"], "Technology_Description": "The goal of SEED is to fundamentally advance the methodology of computer vision by exploiting a dynamic analysis perspective in order to acquire accurate, yet tractable models, that can automatically learn to sense our visual world, localize still and animate objects (e.g. chairs, phones, computers, bicycles or cars, people and animals), actions and interactions, as well as qualitative geometrical and physical scene properties, by propagating and consolidating temporal information, with minimal system training and supervision. SEED will extract descriptions that identify the precise boundaries and spatial layout of the different scene components, and the manner they move, interact, and change over time. For this purpose, SEED will develop novel high-order compositional methodologies for the semantic segmentation of video data acquired by observers of dynamic scenes, by adaptively integrating figure-ground reasoning based on bottom-up and top-down information, and by using weakly supervised machine learning techniques that support continuous learning towards an open-ended number of visual categories. The system will be able not only to recover detailed models of dynamic scenes, but also forecast future actions and interactions in those scenes, over long time horizons, by contextual reasoning and inverse reinforcement learning. Two demonstrators are envisaged, the first corresponding to scene understanding and forecasting in indoor office spaces, and the second for urban outdoor environments. The methodology emerging from this research has the potential to impact fields as diverse as automatic personal assistance for people, video editing and indexing, robotics, environmental awareness, augmented reality, human-computer interaction, or manufacturing.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["648379"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["LUNDS UNIVERSITET", "LUNDS UNIVERSITET"], "EU_Contribution": ["EUR 1 985 818"], "Project_Title": ["The next-generation planet formation model"], "Total_Cost": ["EUR 1 985 818"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["PLANETESYS"], "Technology_Description": "The goal of this ERC Consolidator Grant proposal is to make significant contributions to our understanding of the formation of planetary systems and the chemical composition of planets. I will achieve this by developing a planet formation model that integrates the most relevant physical processes and combines the newly discovered pebble accretion mechanism with gravitational interaction between a high number of growing embryos. Exploiting the results of the computer simulations will allow me to address three major, outstanding research questions in the study of planets and their formation:", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["724687"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER", "THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 147 963,75"], "Project_Title": ["Hybrid Membranes Incorporating Metal-Organic Frameworks"], "Total_Cost": ["EUR 147 963,75"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["MemMOFs"], "Technology_Description": "Research undertaken on ERC Advanced Grant 226593 (COORDSPACE) has delivered a new exciting range of metal organic frameworks (MOFs). These substances show ultra-high porosity and this makes them ideal for many high value commercial applications, including gas separations. Of specific interest is NOTT-300, a unique, porous solid with exceptional, selective, CO2 and SO2 uptake properties and remarkable acetylene vs ethylene, ethylene vs ethane, and CO2 vs CH4 separation abilities. We now target the incorporation of NOTT-300 into gas separation media to impart these systems with the extraordinary properties of NOTT-300 to fulfil an urgent unmet need within a range of industries. This project will develop and deliver a market-ready mixed matrix membrane (MMM) incorporating NOTT-300", "To": ["2017-11-30, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2014 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-12-01"], "Project_ID": ["665632"], "Call_for_Proposal": ["ERC-2014-PoC"]}, -{"Partners": ["STICHTING KATHOLIEKE UNIVERSITEIT"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["Neural correlates of working memory control in aged bilinguals"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["NeWMaBIL"], "Technology_Description": "Identification of factors that slow down cognitive depletion in ageing is today one of the main objectives of the aged society. Within the concept of cognitive reserve (CR), bilingualism has evidenced to shape cognition by enhancing the capacity of cognitive control (CgCnt). CgCnt and working memory (WM) capacities are strongly interrelated systems which are depleted by ageing. However, the exploration of how bilingualism shapes cognition in old populations is scarce and recently subjected to debate. Under this framework, sensitive approaches (such as the exploration of the neural oscillatory activity) that enable objective investigation of the effects of bilingualism on cognitive ageing are necessary. Neural oscillations represent the mechanisms responsible for cognition. Furthermore, they offer a direct measure of the cognitive architecture and of any reorganizational process accounting in the brain by factors as bilingualism. Nevertheless, the neural code of WM control in old bilinguals has not been explored yet. The current project aims to investigate, with magnetoencephalography (MEG), the neural correlates of WM control in young and old adult bilingual individuals. Resulting data will open a window into the role of bilingualism on the neural architecture of the working brain.", "To": ["2017-12-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["657255"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["OBSERVATOIRE DE LA COTE D'AZUR (OCA)", "OBSERVATOIRE DE LA COTE D'AZUR (OCA)"], "EU_Contribution": ["EUR 1 717 811"], "Project_Title": ["Ultimate Angular Resolution Astrophysics with kernel-phase and full-aperture interferometry"], "Total_Cost": ["EUR 1 717 811"], "Country": ["France", "France"], "Project_ACR": ["KERNEL"], "Technology_Description": "Astronomy requires large telescopes to improve the sensitivity and the angular resolution of its observations. Of these qualities, angular resolution is the most difficult to maintain in the optical and near-infrared, since the atmosphere reduces it to that of a 10 cm aperture, regardless of the telescope size. On the one-hand, Adaptive Optics (AO) actively compensates for this effect but the improvement is often partial only. On the other hand, interferometric techniques (most notably sparse aperture masking interferometry) passively allow the extraction of self-calibrating observables, that boost the angular resolution, but severely affect the sensitivity of observations. A framework newly established by the PI of the proposal however now makes it possible to extract generalized self-calibrating observables called kernel-phases from conventional AO-corrected images. The work outlined in this proposal will make it possible to scientifically exploit the high angular resolution imaging capability of this technique, to improve its robustness and to expand its capabilities. The framework offers a very general purpose high angular resolution imaging tool for astronomers as well as wavefront control experts. This proposal is organized in five work-packages of increasing challenge that include: the reinterpretation of existing archival data with a super-resolution capability, the expansion of its robustness to open up new more challenging use-cases, a special focus on the development of a very high-dynamic range mode, the adaptation of interferometric image reconstruction techniques, and the development of new advanced AO concepts. The consequences of this project will have a major impact on the design and scientific exploitation of future high angular resolution instrumentation on the existing generation of 8-10 meter class telescopes as well as on the upcoming generation of 30-40 meter giants, championned by Europe and its E-ELT.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2016-10-01"], "Project_ID": ["683029"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["FUNDACI\u00d3 MARKETS, ORGANIZATIONS AND VOTES IN ECONOMICS"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Peer effects and endogenous network formation"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["PEERS"], "Technology_Description": "The aim of this project is to develop a theoretical and empirical framework to simultaneously study network formation and peer effects in education. The problem is important from a methodological perspective, as there do not exist general purpose estimatable models of social dynamics in Economics which treat the network formation process as endogenous and simultaneously contemplate network effects on behaviour and its feedback on the network formation process. The possibility of understanding the formation of social networks in terms of the characteristics of the agents forming links is severely limited in most applications by the presence of peer effects that alter these characteristics. Conversely one of the main difficulties in measuring peer effects in any context is that peer groups are endogenous. This project will have two main components (1) a theoretical component and (2) an empirical/experimental component. The theoretical component aims to construct and study in detail the properties of some models of peer effects treating network formation endogenously. In the empirical/experimental component I will estimate and test the models by (a) Relying on two datasets, one of which already exists and one of which is under construction, and which I am currently using on two related projects and (b) Building a detailed longitudinal dataset including information on social network structure and various kinds of behaviours and attitudes using surveys and economic experiments .", "To": ["2017-05-31, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2015-06-01"], "Project_ID": ["657332"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["KAROLINSKA INSTITUTET"], "EU_Contribution": ["EUR 173 857,20"], "Project_Title": ["Nano Traction"], "Total_Cost": ["EUR 173 857,20"], "Country": ["Sweden"], "Project_ACR": ["Nano Traction"], "Technology_Description": "In this Marie Sk\u0142odowska-Curie Fellowship project entitled \u201cNano Traction\u201d I will design a platform for the directed autonomous movement of nano- and microparticles. This will be achieved using a completely novel form of traction based on the dynamic covalent attachment of the particles to a surface. Asymmetrically applied redox potentials will induce motion allowing the electrical control of nano- and microparticle motion and the creation of particles that autonomously move and seek out cells that are producing reactive oxygen species a key indicator of disease. This Fellowship will be undertaken under the supervision of Prof. Molly Stevens in the Division of Biomaterials and Regenerative Medicine at the Karolinska Institute (KI), which has the world-leading expertise in functional nanomaterial synthesis, biomaterials engineering, cell biology and tissue engineering crucial to the objectives of this proposal. This ground-breaking new method of particle control at micro and nanometre length scales will have application in many areas including; precision actuation for nanorobotics and microfluidics and; the creation of cell seeking particles for biosensing and the targeted delivery of nanoparticle agents. It will not only initiate new research areas at the cutting edge of nano- and biomaterials science, but will help me to establish my own independent research career following the proposed Fellowship.", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["747414"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["PROCTER & GAMBLE TECHNICAL CENTRESLIMITED", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "THE UNIVERSITY OF BIRMINGHAM", "UNIVERSITY OF BRISTOL", "KATHOLIEKE UNIVERSITEIT LEUVEN", "CONSORZIO INTERUNIVERSITARIO PER LO SVILUPPO DEI SISTEMI A GRANDE INTERFASE", "UNIVERSITEIT GENT", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.", "PROCTER & GAMBLE SERVICES COMPANY NV"], "EU_Contribution": ["EUR 3 908 202,48"], "Project_Title": ["BIOfilm management and CLEANing by leveraging fundamental understanding of biological, chemical and physical combined approaches"], "Total_Cost": ["EUR 3 908 202,48"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom", "United Kingdom", "Belgium", "Italy", "Belgium", "Germany", "Belgium"], "Project_ACR": ["BIOCLEAN"], "Technology_Description": "BIOCLEAN addresses the urgent need to create a sustainable training network across academia, industry and the healthcare sector which will fill the gap in Europe and beyond to produce highly skilled multi-disciplinary young scientists competent in chemistry, engineering and experimental wet lab biology. BIOCLEAN will deliver this network of young scientists who can apply their proven skill sets gained during the project life time to solve industrial and healthcare sector real life biofilm management challenges.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-10-01"], "Project_ID": ["722871"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["LUNDS UNIVERSITET", "LUNDS UNIVERSITET"], "EU_Contribution": ["EUR 2 621 251"], "Project_Title": ["Deciphering cell heterogeneity in tumors using arrays of nanowires to controllably poke single cells in longitudinal studies"], "Total_Cost": ["EUR 2 621 251"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["NanoPokers"], "Technology_Description": "Cancer is responsible for 20% of all deaths in Europe. Current cancer research is based on cell ensemble measurements or on snapshot studies of individual cells. However, cancer is a systemic disease, involving many cells that interact and evolve over time in a complex manner, which cell ensemble studies and snapshot studies cannot grasp. It is therefore crucial to investigate cancer at the single cell level and in longitudinal studies (over time). Despite the recent developments in micro- and nanotechnologies, combined with live cell imaging, today, there is no method available that meets the crucial need for global monitoring of individual cell responses to stimuli/perturbation in real-time. ", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["682206"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["AARHUS UNIVERSITET"], "EU_Contribution": ["EUR 212 194,80"], "Project_Title": ["The influence of Earth-surface processes on solid-Earth, ice-sheet, and sea-level interactions for Scandinavian Ice-Sheet collapse"], "Total_Cost": ["EUR 212 194,80"], "Country": ["Denmark"], "Project_ACR": ["EROSIVE"], "Technology_Description": "One of the grand challenges for society in the future will be to cope with the consequences of a changing climate and resulting changes in global sea level. Yet, predictions of past and future scenarios are associated with significant uncertainties, as we do not currently understand all processes that influence ice-sheet variability and thereby global ice volume. One key shortcoming relates to Earth-surface processes. Fjord formation by selective glacial erosion has the potential to elevate surrounding regions significantly by erosional unloading (~1 km in Greenland). However, the consequences for ice-sheet dynamics and global sea level have never been explored. My approach is to combine state-of-the-art numerical modelling efforts from the two disciplines of sea-level research and glacial geomorphology with empirical data analysis, in order to investigate the influence of such processes on the solid Earth, ice sheets, and sea level. I will apply this novel modelling scheme to study the former Scandinavian Ice Sheet (SIS), where remarkable empirical constraints exist on glacial isostatic rebound, past ice sheet extent, and deposited sediment volumes. By investigating a former ice sheet, I will improve our understanding of processes that are highly relevant for the future evolution of existing ice sheets. This will improve the scientific basis for decision makers to shape well-founded policies for optimal adaptation to future sea-level changes. While acquiring new expertise in glacial geology and sedimentology, I will i) constrain solid-Earth deformation and global sea-level changes due to Quaternary erosion and deposition in the Scandinavian region, ii) assess the influence of long-term glacial erosion for SIS dynamics, ice volume, and sea-level contributions, and iii) gain significant insight into important interactions between surface processes, solid-Earth deformation, ice-sheet variability and sea-level change, and improve our understanding of SIS collapse.", "To": ["2020-07-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-08-01"], "Project_ID": ["745669"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF BATH", "UNIVERSITY OF BRISTOL", "UNIVERSITAT ZURICH", "MICROSEMI SEMICONDUCTOR LIMITED", "MEDTRONIC BAKKEN RESEARCH CENTER B.V.", "MEDIZINISCHE UNIVERSITAET WIEN", "UNIVERSITAIR MEDISCH CENTRUM UTRECHT", "FAKULTNI NEMOCNICE U SV. ANNY V BRNE"], "EU_Contribution": ["EUR 4 944 347,50"], "Project_Title": ["Adaptive Bio-electronics for Chronic Cardiorespiratory Disease"], "Total_Cost": ["EUR 4 944 347,50"], "Country": ["United Kingdom", "United Kingdom", "Switzerland", "United Kingdom", "Netherlands", "Austria", "Netherlands", "Czech Republic"], "Project_ACR": ["CResPace"], "Technology_Description": "This consortium will pioneer disruptive technology for bio-electronic medicine to provide much needed therapies for cardiorespiratory and functional neurological disease. The technology implements small neural networks known as central pattern generators (CPG) to deliver fit-and-forget bio-electronic implants that respond to physiological feedback in real time, are safer, simpler, non-invasive, and have autonomy exceeding the patient lifespan. Multichannel neurons will be made to compete on analogue chips to obtain flexible motor sequences underpinned by a wide parameter space. By building large scale nonlinear optimization tools and using them to assimilate electrophysiological data, we will develop a method for automatically finding the network parameters that accurately reproduce biological motor sequences and their adaptation to multiple physiological inputs. In this way, we will have resolved the issue of programming analogue CPGs which has long been the obstacle to using neural chips in medicine. An adaptive pacemaker will be constructed, tested, validated and trialled on animal models of atrio-ventricular block and left bundle branch block to demonstrate the benefits of heart rate adaptation, beat-to-beat cardiac resynchronization and respiratory sinus arrhythmia. By providing novel therapy for arrhythmias, heart failure and their comorbidities such as sleep apnoea and hypertension, CResPace will extend patients\u2019 life and increase quality of life.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["FETPROACT-01-2016 - FET Proactive: emerging themes and communities"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["732170"], "Call_for_Proposal": ["FETPROACT-2016"]}, -{"Partners": ["UNIVERSITY OF BRISTOL", "BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY"], "EU_Contribution": ["EUR 251 857,80"], "Project_Title": ["The Basal Roughness of Ice Sheets from Radio-Echo Sounding"], "Total_Cost": ["EUR 251 857,80"], "Country": ["United Kingdom", "United States"], "Project_ACR": ["BRISRES"], "Technology_Description": "The subglacial environment beneath the Greenland and Antarctic ice sheets is one of the physically least well characterised environments on Earth. Ice sheet model simulations demonstrate high sensitivity to their basal sliding parameterisation which is governed by basal roughness, the thermal state of the bed, and lithology (presence or absence or deformable sediments). Compiling observations of the current state of the glacier bed is therefore crucial for the accuracy of ice sheet modelling and future predictions of sea level change. Radio-echo sounding (RES) is the only existing geophysical technique that has sufficient data coverage to enable ice-sheet-wide information to be obtained from the bed. In general, however, quantitative analysis of radar sounding data, and integration with electromagnetic and geostatistical approaches, lags significantly behind the data availability.", "To": ["2020-08-20, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-08-21"], "Project_ID": ["747336"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ITA-SUOMEN YLIOPISTO", "EBERHARD KARLS UNIVERSITAET TUEBINGEN", "THE QUEEN'S UNIVERSITY OF BELFAST", "UNIVERSITE DE STRASBOURG", "TECHNISCHE UNIVERSITEIT EINDHOVEN", "UNIVERSITA DEGLI STUDI DI PADOVA", "UNIVERSITEIT UTRECHT", "OZ BIOSCIENCES SAS", "SIMCYP LIMITED"], "EU_Contribution": ["EUR 3 933 729,36"], "Project_Title": ["Educational Network in Ocular Drug Delivery and Therapeutics"], "Total_Cost": ["EUR 3 933 729,36"], "Country": ["Finland", "Germany", "United Kingdom", "France", "Netherlands", "Italy", "Netherlands", "France", "United Kingdom"], "Project_ACR": ["OcuTher"], "Technology_Description": "Ocular drug development has transformed from niche area to a major field in drug development in which many companies, including European big pharma has entered recently. Ocular drug development is a unique field in terms of drug targets and end-points of activity, local drug administration routes, tissue barriers and pharmacokinetics, drug delivery and formulation challenges and local toxicity issues. These issues are slowing down the development of drugs for the unmet needs in ophthalmology. The main objective of the proposal is to educate experts of preclinical ocular R&D to facilitate the success of European pharmaceutical industry and research community. This objective will be reached by joining forces of the leading European academic and industrial researchers in ophthalmology, materials science and nanomedicine, drug delivery and targeting, and systems pharmacology. We shall educate 15 Early Stage Researchers in a network where they will receive tailored, multi-disciplinary and inter-sectoral education in preclinical ocular drug development. The thesis projects are directed to the drug treatment of retinal diseases, the major challenge in the field. The proposal combines new drug candidates from the experts of ophthalmology, innovative drug delivery technologies from pharmaceutical scientists and companies, and modern in vitro, in silico and in vivo methods from various partners. The thesis projects include secondments in academic and industrial partner laboratories and course programme that encompasses the relevant fields in ocular drug development. Therefore, this proposal presents unique combination of innovation and education in the field with obvious need for such education. The ESRs and other outcomes of this project will greatly benefit the future competitiveness of European science and industry in this field of expanding importance.", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-11-01"], "Project_ID": ["722717"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "ALBERT-LUDWIGS-UNIVERSITAET FREIBURG", "KLINIKUM DER UNIVERSITAET ZU KOELN", "ACADEMISCH ZIEKENHUIS LEIDEN", "MEDIZINISCHE UNIVERSITAET WIEN", "TECHNISCHE UNIVERSITAET WIEN", "FUNDACION PARA LA INVESTIGACION MEDICA APLICADA FIMA", "UNIVERSITY OF BRISTOL", "UNIVERSITAETSKLINIKUM WUERZBURG - KLINIKUM DER BAYERISCHEN JULIUS-MAXIMILIANS-UNIVERSITAT", "STRATEC CONSUMABLES GMBH"], "EU_Contribution": ["EUR 2 539 859,76"], "Project_Title": ["European Network on Anti-Cancer Immuno-Therapy Improvement by modification of CAR and TCR Interactions and Nanoscale Geometry"], "Total_Cost": ["EUR 2 539 859,76"], "Country": ["Spain", "Germany", "Germany", "Netherlands", "Austria", "Austria", "Spain", "United Kingdom", "Germany", "Austria"], "Project_ACR": ["EN_ACTI2NG"], "Technology_Description": "The EN-ACTI2NG program (European Network on Anti-Cancer Immuno-Therapy Improvement by modification of CAR and TCR Interactions and Nanoscale Geometry) emanates from the recent clinical evidence that T cells expressing engineered tumor-specific immune receptors can eradicate certain tumors that do not respond to conventional treatment. To obtain T cells with reactivity to a wider array of tumors and to improve efficiency and on- and off-target toxicity are current challenges Therefore the EN-ACTI2NG program aims 1) to train PhD students with expertise in development of new and improved T cell-mediated cancer immuno-therapies; 2) to endow the PhD students with the ability to establish efficient communication between the academic and industrial research environments and between scientists and the general public; 3) to improve T cell mediated anti-cancer immuno-therapy by the identification and development of new cancer-specific immune receptors and enhancing their function by identifying and modifying their molecular mechanism of action. To reach these objectives we have designed individual research projects ranging from biophysical analysis of immune receptors, via molecular modification of their structure and testing their tumor killing capacity in cell-based and pre-clinical assays to product development. Secondments will assure that each PhD student will be exposed to these complementary approaches and that there will be synergic feedback between the projects, producing innovative results that could otherwise not be achieved. Extensive training in research-specific skills, career development and a continuous training in communication skills will allow the PhD students to become facilitators of the process of transformation of scientific innovation into products with social and economic value. As such, the EN-ACTI2NG program should contribute to overcoming the more general challenge of converting the European Community into an innovation-driven society.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["721358"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["GENOME RESEARCH LIMITED"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Unravelling host intestine-parasite interactions that define immune responses to whipworms"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["GUTWORM"], "Technology_Description": "Whipworms (Trichuris trichuira) are soil-transmitted helminths that infect about 700 million people in the tropics and sub-tropics and cause the human disease, trichuriasis. Whipworms live preferentially in the cecum of their hosts where they tunnel through epithelial cells and cause inflammation potentially resulting in colitis. Despite extensive research, the role of whipworm interactions with epithelial and immune cells in triggering parasite expulsion remains unclear, hindering the development of anti-parasite therapies. The ultimate goal of my research proposal is to investigate and understand this interaction in detail. To achieve this, I will use T. muris, a mouse model of T. trichuira infection in humans. This research proposal has three key aims. First, to identify new parasite and host genes that could interplay and modulate immunological outcomes. Second, to characterize the role of host genes in whipworm infection and immunity. Here, novel and known candidate mutations conferring susceptibility to colitis identified through the Wellcome Trust Sanger Institute - Mouse Genetics Project will be targeted. Thus, I will challenge mutant mouse lines with T. muris and evaluate the influence of these mutations on anti-parasite immunity and expulsion. Finally, upon identification of key genes regulating the immune response to whipworms, I will explore the mechanism of action of selected genes and their effect on the parasite. For this, I will take advantage of the vast range of \u2018omic\u2019 technologies and facilities available at the WTSI. This project will generate novel fundamental data on host-whipworms interactions and also support future efforts to control these parasites by the identification of potential new therapeutic targets. Moreover, resulting knowledge of the parasiteimmunological interplay could be exploited to understand other intestinal inflammatory diseases such as ulcerative colitis that have many similarities with trichuriasis.", "To": ["2017-09-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations"], "From": ["2015-10-01"], "Project_ID": ["656347"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["JACOBS UNIVERSITY BREMEN GGMBH", "RASDAMAN GMBH", "PLYMOUTH MARINE LABORATORY", "EUROPEAN CENTRE FOR MEDIUM-RANGE WEATHER FORECASTS", "METEOROLOGICAL AND ENVIRONMENTAL EARTH OBSERVATION SRL", "COMMUNICATION & INFORMATION TECHNOLOGIES EXPERTS ANONYMOS ETAIREIA SYMVOULEFTIKON KAI ANAPTYXIAKON YPIRESION", "THE AUSTRALIAN NATIONAL UNIVERSITY"], "EU_Contribution": ["EUR 2 839 743"], "Project_Title": ["Agile Analytics on Big Data Cubes"], "Total_Cost": ["EUR 2 839 743,75"], "Country": ["Germany", "Germany", "United Kingdom", "United Kingdom", "Italy", "Greece", "Australia"], "Project_ACR": ["EarthServer-2"], "Technology_Description": "EarthServer-2 makes Agile Analytics on Big Earth Data Cubes of sensor, image, simulation, and statistics data a commodity for non-experts and experts alike through", "To": ["2018-04-30, ongoing project"], "Meta": [""], "Topic_s": ["EINFRA-1-2014 - Managing, preserving and computing with big research data"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2015-05-01"], "Project_ID": ["654367"], "Call_for_Proposal": ["H2020-EINFRA-2014-2"]}, -{"Partners": ["JACOBS UNIVERSITY BREMEN GGMBH", "JACOBS UNIVERSITY BREMEN GGMBH"], "EU_Contribution": ["EUR 2 312 481"], "Project_Title": ["Holomorphic Dynamics connecting Geometry, Root-Finding, Algebra, and the Mandelbrot set"], "Total_Cost": ["EUR 2 312 481"], "Country": ["Germany", "Germany"], "Project_ACR": ["HOLOGRAM"], "Technology_Description": "Dynamical systems play an important role all over science, from celestial mechanics, evolution biology and economics to mathematics. Specifically holomorphic dynamics has been credited as \u201cstraddling the traditional borders between pure and applied mathematics\u201d. Activities of numerous top-level mathematicians, including Fields medalists and Abel laureates, demonstrate the attractivity of holomorphic dynamics as an active and challenging research field.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["695621"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["IE UNIVERSIDAD"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Between Social Values and Profitable Performance: The Case of B-Corporations"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["BCorp"], "Technology_Description": "How entrepreneurs could profit from social responsible investments? This issue implies a balance between entrepreneurs\u2019 investments in profitable business models and their engagement in non-profit social actions. To address this question, the project studies the B-Corporations as a new legal business form of corporations (private and public) pursuing benefits for society and shareholders. A non-profit certifying organization, B-Lab, analyses the impact of these companies on society, with particular attention to their ability to provide to \u2018communities\u2019 beneficial products or services. Although first established in US, now they are present in 34 countries across 121 industries. Employing this legal form of social companies, the proposal exploits the notion of community-focused strategies (CFS) to refer to the actions that entrepreneurs should pursue to establish links with communities to fulfill reciprocal social values. If people join communities to satisfy their identity needs, entrepreneurs might seek to align their ventures\u2019 strategy to them to improve entrepreneurial performance. Building on social identity theory, entrepreneurial and strategy research, this project adopt mainly a demand-oriented approach. First, it tries to explain differences in new ventures\u2019 performance investigating how B-Corps interact with their communities and through them access customers\u2019 information and gaining loyalty. Second, it explores and profiles the B-Corps as new examples of social entrepreneurial ventures. Finally, it studies entrepreneurs\u2019 strategies to develop long-term interactions with the communities. The statistical evidence is drawn from secondary data, surveys to entrepreneurs, and lab experiments. Implications on ventures\u2019 success rate, growth and drawbacks of the interplay between social entrepreneurship and CFS are discussed.", "To": ["2018-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["655676"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["EUROPEAN MOLECULAR BIOLOGY LABORATORY", "UNIVERSITAIR MEDISCH CENTRUM UTRECHT", "FUNDACIO INSTITUT DE CIENCIES FOTONIQUES", "FUNDACIO CENTRE DE REGULACIO GENOMICA", "UNIVERSITY OF DUNDEE", "BIOBANKS AND BIOMOLECULAR RESOURCES RESEARCH INFRASTRUCTURE CONSORTIUM (BBMRI-ERIC)", "IDRYMA IATROVIOLOGIKON EREUNON AKADEMIAS ATHINON", "ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM", "EATRIS ERIC", "ECRIN EUROPEAN CLINICAL RESEARCH INFRASTRUCTURE NETWORK", "THE UNIVERSITY OF LIVERPOOL", "ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI", "HEINRICH-HEINE-UNIVERSITAET DUESSELDORF", "INFRAFRONTIER GMBH", "HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH", "INSTRUCT ACADEMIC SERVICES LIMITED", "CONSORZIO INTERUNIVERSITARIO RISONANZE MAGNETICHE DI METALLO PROTEINE", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "STAZIONE ZOOLOGICA ANTON DOHRN", "THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS", "FORSCHUNGSVERBUND BERLIN EV", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN", "THE UNIVERSITY OF MANCHESTER", "STICHTING VU", "DEUTSCHES KREBSFORSCHUNGSZENTRUM", "LEIBNIZ-INSTITUT DSMZ-DEUTSCHE SAMMLUNG VON MIKROORGANISMEN UND ZELLKULTUREN GMBH*", "JACOBS UNIVERSITY BREMEN GGMBH", "KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW", "CSC-TIETEEN TIETOTEKNIIKAN KESKUS OY", "CAB INTERNATIONAL", "MEDIZINISCHE UNIVERSITAET WIEN", "ACADEMISCH ZIEKENHUIS GRONINGEN", "UNIVERSITA DEGLI STUDI DI TORINO"], "EU_Contribution": ["EUR 14 837 800"], "Project_Title": ["Coordinated Research Infrastructures Building Enduring Life-science services"], "Total_Cost": ["EUR 14 837 800"], "Country": ["Germany", "Netherlands", "Spain", "Spain", "United Kingdom", "Austria", "Greece", "Netherlands", "Netherlands", "France", "United Kingdom", "Italy", "Germany", "Germany", "Germany", "United Kingdom", "Italy", "Spain", "France", "Italy", "United Kingdom", "Germany", "United Kingdom", "Germany", "United Kingdom", "Netherlands", "Germany", "Germany", "Germany", "Netherlands", "Finland", "United Kingdom", "Austria", "Netherlands", "Italy"], "Project_ACR": ["CORBEL"], "Technology_Description": "The social and economic challenges of ageing populations and chronic disease can only be met by translation of biomedical discoveries to new, innovative and cost effective treatments. The ESFRI Biological and Medical Research Infrastructures (BMS RI) underpin every step in this process; effectively joining scientific capabilities and shared services will transform the understanding of biological mechanisms and accelerate its translation into medical care.", "To": ["2019-08-31, ongoing project |"], "Meta": [""], "Topic_s": ["INFRADEV-4-2014-2015 - Implementation and operation of cross-cutting services and solutions for clusters of ESFRI and other relevant research infrastructure initiatives"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Germany"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Other", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Other", "Research Organisations", "Other", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Other", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["654248"], "Call_for_Proposal": ["H2020-INFRADEV-1-2014-1"]}, -{"Partners": ["HAUS DER WISSENSCHAFT BRAUNSCHWEIG GMBH", "TECHNISCHE UNIVERSITAET BRAUNSCHWEIG"], "EU_Contribution": ["EUR 189 000"], "Project_Title": ["Crossing Borders - In jedem steckt ein Forscher / European Researchers Night 2014 + 2015"], "Total_Cost": ["EUR 189 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["BS_Night_140926_150925"], "Technology_Description": "Crossing Borders, pushing the limits of knowledge, inventing new methods, technologies, materials to improve our life. That\u00b4s what research is all about. What is needed for this is simple: a clever mind and curiosity. With the slogan Crossing Borders \u2013there is a researcher in all of us we want to show how diverse research careers and findings can be and how they impact the everyday life. Furthermore, during the European Researchers\u00b4 Night we want to advertise research as a career especially to young people. This is why we are bringing researchers into town - research is right at home in Braunschweig. Our region is one of the most research intensive regions in Europe, boasting the highest density of scientists. To make this visible we are embarking in a bet: we want to assemble at least 1,000 researchers at a so-called Researcher-Flashmob. We expect around 10,000 visitors who are invited to be part of the bet before the event and who can be part of a whole range of small events on the night to get up-and-close with the researchers. Events include playing games together, an elevator pitch, hands-on-experiments or a Science Slam. This way we are encouraging people to enjoy research and show how research makes life easier. At the same time we dispel the myth surrounding researchers. An extensive awareness campaign before the event will help spreading the message even beyond the night itself. After the campaign we expect at least 85,000 people to know about the European Researchers\u00b4 Night (ERN) and its objectives. ", "To": ["2015-10-31, closed project |"], "Meta": [""], "Topic_s": ["MSCA-NIGHT-2014 - European Researchers' Night (NIGHT)"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Germany"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2014-05-01"], "Project_ID": ["633320"], "Call_for_Proposal": ["H2020-MSCA-NIGHT-2014"]}, -{"Partners": ["UNIVERSITATEA POLITEHNICA DIN BUCURESTI"], "EU_Contribution": ["EUR 137 422,80"], "Project_Title": ["LV DC microgrids for evolved energy communities"], "Total_Cost": ["EUR 137 422,80"], "Country": ["Romania"], "Project_ACR": ["DCNextEve"], "Technology_Description": "Microgrids are an important concept in the emerging power industry field. They are widely recognized as an innovative eco-system when it comes to a flexible and reliable option for the integration of distributed energy renewable resources (DER). The research on direct current (DC) power distribution systems is taking ground especially for applications where the end-use loads are natively DC (e.g. data centers, offices, residential). Efficiency, reliability, lower capital cost, simpler control strategies, higher power quality are the most cited advantages compared with AC microgrids. The primary technical research objective of this project is the design and analysis of novel methods for management and control of multiple building scale DC microgrids operating on a defined territory. Specifically the major technical objectives are: (a)To enhance the state of the art in the DC microgrid field with a holistic design, modelling, control framework for clusters of LV building level DC microgrids (the emerging community prosumers of tomorrow;) (b) To develop and validate models for typical elements of DC microgrids. The models will follow an innovative and yet unexplored approach based on hybrid dynamic system analysis; (c) To develop and test models for optimal operation of clusters of DC microgrids under uncertainty. The optimization models will look for different objectives to be optimized while taking into account the technical and economic constraints of the systems operating in either stand-alone or interconnected mode; (d) To develop and validate distributed control schemes for ad-hoc clusters of DC microgrids. Career development objectives are: (a) To enhance the research skills of the Fellow with complementary knowledge in power quality, modeling and control specific for DC grids, (b) To facilitate the transfer of knowledge to the society, scientific community and industry and to explore the commercial potential of the research outcomes.", "To": ["2018-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Romania"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-07-01"], "Project_ID": ["708844"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["TECHNISCHE UNIVERSITAET BRAUNSCHWEIG"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Identification of cellular identities and characterization of the STAT3 signalling pathway in Purkinje cell layer regeneration"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["PURKINJEREG"], "Technology_Description": "There are many degenerative diseases affecting the cerebellum (as certain cerebellar ataxia) with severe locomotor symptoms, in which the Purkinje cells (PCs), the sole-output cerebellar neurons, suffer from degeneration. The adult regenerative capacity of neurons in mammals is extremely low. However, the zebrafish is a model organism that exhibits extensive adult neurogenesis and regeneration, and is therefore most likely to elucidate key cerebellar regenerative mechanisms that are currently unknown. The proposed project will focus on the study of PC regeneration using an inducible cell type specific ablation technique, in which the recovery of PCs cannot involve the plasticity of remaining cells, making this tool superior to existing protocols which rely on mechanical injuries. In such PC-ablated zebrafish the time course of PC layer recovery will be analyzed by behavioral tests, which will also reveal specific functions of the zebrafish cerebellum. Cellular processes of regeneration will be revealed by the analysis of double transgenic zebrafish strains addressing: the cellular sources of regenerating PC progenitors, their spatial distribution, potential migratory routes of de novo differentiating PCs, and cellular interactions accompanying a proper restoration of a functional PC layer. We also expect to obtain first insights into potential molecular processes involved in the degeneration-regeneration processes of PCs, considering Stat3- signaling (with important roles in tissue restoration) as a promising candidate to promote PC regeneration by employing inhibitor studies, and to derive functional consequences for the organism. These results are fundamental to understanding and eventually treating diseases affecting the cerebellum. Therefore, these studies about PCs regeneration in zebrafish will reach beyond basic research by revealing molecular and cellular potentials and constraints for neuronal regeneration therapeutic approaches in the vertebrate brain.", "To": ["2018-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-07-01"], "Project_ID": ["703961"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["NEW BULGARIAN UNIVERSITY", "TRAKIYSKI UNIVERSITET", "PLOVDIVSKI UNIVERSITET PAISIY HILENDARSKI", "MEDITCINSKY UNIVERSITET-PLOVDIV", "UNIVERSITY OF RUSE ANGEL KANCHEV", "Medical University Of Varna", "JOINT INNOVATION CENTRE OF BAS", "THE BRITISH COUNCIL"], "EU_Contribution": ["EUR 201 000"], "Project_Title": ["Researchers in the Knowledge Triangle"], "Total_Cost": ["EUR 248 645"], "Country": ["Bulgaria", "Bulgaria", "Bulgaria", "Bulgaria", "Bulgaria", "Bulgaria", "Bulgaria", "United Kingdom"], "Project_ACR": ["K-TRIO 2"], "Technology_Description": "The K-TRIO 2 consortium organized in several years Researchers\u2019 Night in Bulgaria in different cities making people and especially children and youth aware of researchers\u2019 profession and the contribution of research to economy and society. The public opinion surveys show that the Researchers\u2019 Night became a popular event in many Bulgarian cities. People enjoy the variety of activities offered and would like to make the Researchers\u2019 Night a regular \u201cFall rendez-vous\u201d in their city with a lot of fun and interaction with researchers.", "To": ["2015-11-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-NIGHT-2014 - European Researchers' Night (NIGHT)"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Bulgaria"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other"], "From": ["2014-06-01"], "Project_ID": ["633175"], "Call_for_Proposal": ["H2020-MSCA-NIGHT-2014"]}, -{"Partners": ["UNIVERSITE PARIS-SUD", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "JACOBS UNIVERSITY BREMEN GGMBH", "UNIVERSITE GRENOBLE ALPES", "UNIVERSITE JOSEPH FOURIER GRENOBLE 1", "TECHNISCHE UNIVERSITAET KAISERSLAUTERN", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "UNIWERSYTET SLASKI", "THE UNIVERSITY OF SHEFFIELD", "UNIVERSITY OF SOUTHAMPTON", "THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS", "UNIVERSITE DE VERSAILLES SAINT-QUENTIN-EN-YVELINES.", "THE UNIVERSITY OF WARWICK", "UNIVERSITAT ZURICH", "LOGILAB", "SIMULA RESEARCH LABORATORY AS", "UNIVERSITEIT GENT", "EUROPEAN X-RAY FREE-ELECTRON LASERFACILITY GMBH", "FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG"], "EU_Contribution": ["EUR 7 633 845,50"], "Project_Title": ["Open Digital Research Environment Toolkit for the Advancement of Mathematics"], "Total_Cost": ["EUR 7 643 071,25"], "Country": ["France", "France", "Germany", "France", "France", "Germany", "United Kingdom", "Poland", "United Kingdom", "United Kingdom", "United Kingdom", "France", "United Kingdom", "Switzerland", "France", "Norway", "Belgium", "Germany", "Germany"], "Project_ACR": ["OpenDreamKit"], "Technology_Description": "OpenDreamKit will deliver a flexible toolkit enabling research groups to set up Virtual Research Environments, customised to meet the varied needs of research projects in pure mathematics and applications and supporting the full research life-cycle from exploration, through proof and publication, to archival and sharing of data and code.", "To": ["2019-08-31, ongoing project |"], "Meta": [""], "Topic_s": ["EINFRA-9-2015 - e-Infrastructures for virtual research environments (VRE)"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["676541"], "Call_for_Proposal": ["H2020-EINFRA-2015-1"]}, -{"Partners": ["THE OPEN UNIVERSITY", "OBSERVATOIRE DE PARIS", "UNIVERSITY COLLEGE LONDON", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "INSTITUTO NACIONAL DE TECNICA AEROESPACIAL ESTEBAN TERRADAS", "STICHTING VU", "SCIENOFFICE, COMUNICACAO DE CIENCIA LDA", "OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN", "INTERNATIONAL RESEARCH SCHOOL OF PLANETARY SCIENCES", "ILMATIETEEN LAITOS", "DEUTSCHES ZENTRUM FUER LUFT - UND RAUMFAHRT EV", "ABERYSTWYTH UNIVERSITY", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "NATURAL HISTORY MUSEUM", "JACOBS UNIVERSITY BREMEN GGMBH", "ISTITUTO NAZIONALE DI ASTROFISICA", "AARHUS UNIVERSITET", "MAGYAR TUDOMANYOS AKADEMIA WIGNER FIZIKAI KUTATOKOZPONT", "USTAV FYZIKY ATMOSFERY AV CR, v.v.i.", "MATIS OHF", "WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER", "FONDATION EUROPEENNE DE LA SCIENCE", "GFI INFORMATIQUE SA", "CORIOLYS", "MEDIZINISCHE UNIVERSITAT GRAZ", "INSTITUT ROYAL D'AERONOMIE SPATIALEDE BELGIQUE", "LATVIJAS UNIVERSITATE", "UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA", "INSTYTUT NAUK GEOLOGICZNYCH POLSKIEJ AKADEMII NAUK", "VILNIAUS UNIVERSITETAS", "INSTITUTE OF ACCELERATING SYSTEMS AND APPLICATIONS", "UNIVERSITEIT LEIDEN", "CENTRUM BADAN KOSMICZNYCH POLSKIEJ AKADEMII NAUK", "STIFTUNG INTERNATIONAL SPACE SCIENCE INSTITUTE"], "EU_Contribution": ["EUR 9 945 361"], "Project_Title": ["EUROPLANET 2020 Research Infrastructure"], "Total_Cost": ["EUR 10 234 226,05"], "Country": ["United Kingdom", "France", "United Kingdom", "France", "Spain", "Netherlands", "Portugal", "Austria", "Italy", "Finland", "Germany", "United Kingdom", "Germany", "United Kingdom", "Germany", "Italy", "Denmark", "Hungary", "Czech Republic", "Iceland", "Germany", "France", "France", "France", "Austria", "Belgium", "Latvia", "Spain", "Poland", "Lithuania", "Greece", "Netherlands", "Poland", "Switzerland"], "Project_ACR": ["EPN2020-RI"], "Technology_Description": "The Europlanet 2020 Research Infrastructure (EPN2020-RI) will address key scientific and technological challenges facing modern planetary science by providing open access to state-of-the-art research data, models and facilities across the European Research Area. Its Transnational Access activities will provide access to world-leading laboratory facilities that simulate conditions found on planetary bodies as well as specific analogue field sites for Mars, Europa and Titan. Its Virtual Access activities will make available the diverse datasets and visualisation tools needed for comparing and understanding planetary environments in the Solar System and beyond. By providing the underpinning facilities that European planetary scientists need to conduct their research, EPN2020-RI will create cooperation and effective synergies between its different components: space exploration, ground-based observations, laboratory and field experiments, numerical modelling, and technology.", "To": ["2019-08-31, ongoing project |"], "Meta": [""], "Topic_s": ["INFRAIA-1-2014-2015 - Integrating and opening existing national and regional research infrastructures of European interest"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations"], "From": ["2015-09-01"], "Project_ID": ["654208"], "Call_for_Proposal": ["H2020-INFRAIA-2014-2015"]}, -{"Partners": ["UNIVERSITY OF LEEDS", "UNIVERSIDAD DE CANTABRIA", "EIDGENOESSISCHE ANSTALT FUER WASSERVERSORGUNG ABWASSERREINIGUNG UND GEWAESSERSCHUTZ", "NORSK INSTITUTT FOR VANNFORSKNING", "THE UNIVERSITY OF BIRMINGHAM", "FORSCHUNGSVERBUND BERLIN EV", "STICHTING IHE DELFT", "HELMHOLTZ-ZENTRUM FUER UMWELTFORSCHUNG GMBH - UFZ", "UNIVERSITA DEGLI STUDI DI TRENTO", "NATURAL ENVIRONMENT RESEARCH COUNCIL"], "EU_Contribution": ["EUR 3 923 988,84"], "Project_Title": ["A EUROpean training and research network for environmental FLOW management in river basins"], "Total_Cost": ["EUR 3 923 988,84"], "Country": ["United Kingdom", "Spain", "Switzerland", "Norway", "United Kingdom", "Germany", "Netherlands", "Germany", "Italy", "United Kingdom"], "Project_ACR": ["EUROFLOW"], "Technology_Description": "A EUROpean training and research network for environmental FLOW management in river basins", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["765553"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["TECHNISCHE UNIVERSITAET BRAUNSCHWEIG", "TECHNISCHE UNIVERSITAET BRAUNSCHWEIG"], "EU_Contribution": ["EUR 1 994 250"], "Project_Title": ["Gain by Strain: Precise Cuts of Cyclopropanes as Key to Molecular Complexity"], "Total_Cost": ["EUR 1 994 250"], "Country": ["Germany", "Germany"], "Project_ACR": ["GAINBYSTRAIN"], "Technology_Description": "A central discipline of chemistry is the design und creation of molecules with defined structural and chemical properties. Stretching synthetic horizons is a never-ending endeavor to inspirit the chemist\u2019 s creativity in preparing compounds and materials yet to be discovered. Relying on their high strain energy cyclopropanes, as carriers of the most fundamental ring geometry, offer a unique reactivity which allows for a multitude of transformations being grouped in ring-opening reactions, cycloadditions and rearrangements. Major advantage of all these processes is the cyclopropane-derived intrinsic atom-economy.", "To": ["2020-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-07-01"], "Project_ID": ["648711"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["JACOBS UNIVERSITY BREMEN GGMBH", "TECHNISCHE UNIVERSITAET MUENCHEN"], "EU_Contribution": ["EUR 159 795,60"], "Project_Title": ["Towards Intelligent Cognitive AUVs"], "Total_Cost": ["EUR 159 795,60"], "Country": ["Germany", "Germany"], "Project_ACR": ["TIC-AUV"], "Technology_Description": "In recent years, long-term autonomy and persistent autonomy have ecome key areas of interest for marine robotics researchers. Ocean observatories require autonomous robot deployments over months or years. Deep-water oilfield inspection and intervention with autonomous vehicles is now a commercial reality, but fielded robots rely heavily on accurate a priori models of the subsea assets. Robustness to errors in autonomous contact tasks requires detection of execution errors.", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-03-01"], "Project_ID": ["709136"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE"], "EU_Contribution": ["EUR 175 419,60"], "Project_Title": ["Association of Uranium with Organic Matter- and Iron-bearing Colloids in Wetland Environments"], "Total_Cost": ["EUR 175 419,60"], "Country": ["Switzerland"], "Project_ACR": ["UMIC"], "Technology_Description": "In the context of decreasing water standards for uranium (U) concentrations in drinking water, the use of natural or constructed wetlands is often proposed for cost-effective small-scale water treatment. The underlying mechanism is immobilization of the dissolved form of uranium, U(VI), through its reduction to a less mobile form, U(IV). However, the long-term stability of U(IV) species formed is not well understood. Indeed, a significant amount of U is found labile, even in its reduced form, and contaminates the hydrologic network in several sites. Previous studies suggest that the colloidal phase is responsible for the dispersion of U(IV) in the watershed. In addition, it has been hypothesized that the propensity of the colloidal phase to bind and mobilize U(IV) depends on the association of Fe with colloidal natural organic matter (NOM), and on the colloids conformation. However, these hypotheses need to be investigated and information is lacking on the processes leading to the formation of the pressented vector of U(IV) dissemination, i.e. Fe-NOM colloids. Understanding these processes is crucial for predicting the efficiency of wetlands as traps of U water contamination. We propose to (i) further characterize wetland colloids, in a broader panel of wetlands, and use correlation analysis to pinpoint factors controlling the NOM shape and its ability for Fe- and U-binding; (ii) test in batch experiments the effect of Fe sources on NOM properties in solution; and (iii) test the reactivity of Fe-NOM colloids with U(IV) and identify the U(IV) binding mechanisms at molecular levels. The original approach proposed will help decision making for uses of wetland filters, and also generate fundamental knowledge about NOM reactivity. The project involves the state-of-the-art expertise of the host institute (EPFL) about U geochemistry in wetlands, and the complementary expertise of Geneva University about characterization of colloidal organic matter.", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["701542"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["TECHNISCHE UNIVERSITAET GRAZ", "UNIVERSITAET GRAZ", "UNIVERSIDADE DO PORTO", "TECHNISCHE UNIVERSITAT HAMBURG-HARBURG", "RUHR-UNIVERSITAET BOCHUM", "WAGENINGEN UNIVERSITY", "UNIVERSITE D'AIX MARSEILLE"], "EU_Contribution": ["EUR 3 029 223,96"], "Project_Title": ["Light-driven sustainable biocatalysis training network"], "Total_Cost": ["EUR 3 029 223,96"], "Country": ["Austria", "Austria", "Portugal", "Germany", "Germany", "Netherlands", "France"], "Project_ACR": ["PhotoBioCat"], "Technology_Description": "Pharmaceutical and chemical products present in everyday life are currently obtained from waste- and energy-intensive processes. Alternative routes that overcome this waste challenge should offer a cleaner and long-lasting solution. PhotoBioCat aims at developing efficient and sustainable light-driven enzyme-catalyzed chemical processes to a commercial industrial level. The PhotoBioCat EJD will train 12 ESRs in cutting edge research projects on (i) the development of chemical and biological catalytic systems for the synthetic use of visible light for the production of pharmaceuticals, bulk-, fine- and specialty chemicals, (ii) up-scaling and optimization of commercially relevant processes together with industry, (iii) defining a road-map for the industrial implementation of photobiocatalysis. The double degree program allows in-depth training in two complementary disciplines, further strengthened by a transferable skills training with strong industry participation.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EJD - European Joint Doctorates"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["764920"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["TECHNISCHE UNIVERSITAET BRAUNSCHWEIG"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["SINGLE-MOLECULE DNA SEQUENCING THROUGH DNA ORIGAMI NANOANTENNAS."], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["Origami-SEQ"], "Technology_Description": "The inner working of many fundamental biological nanomachines implies many stochastic changes in conformation and molecular interactions. These changes are reflected as variability in the activity of the same molecule over time, and in heterogeneous activities between different molecules. By the direct observation at the molecular scale of these nanomachines activity, single-molecule fluorescence techniques have gained access to this stochastic information, which is otherwise missed by bulk techniques but is essential for their understanding. However, the widespread use of these techniques in many biological systems has been hampered by the low working concentration (nM) determined by the diffraction limit of light, and current nanophotonic solutions to this problem are technically too demanding. Here, we propose self-assembled DNA origami nanoantennas as nanophotonic platforms aiming to break this concentration barrier by means of fluorescence signal enhancing and reduction of the observation volume. The versatility of DNA origami structures, biocompatibility and ability for site-directed immobilization of biomolecules, make them perfectly suited to perform complex biological assays. In the presented action we aim to achieve single-molecule fluorescence DNA sequencing using DNA origami nanoantennas to probe the potential of these platforms to perform complex bioassays, in the high concentration regime and demanding multiplexing. Moreover, since they avoid the fabrication and instrumental challenges related to other nanophotonic devices, self-assembly DNA origami nanoantennas are amenable, easy to handle and friendly technology to the biological experimenter, and thus we expect to boost their use in biology. Besides, the fulfilment of this action will provide the fellow with a complete formative training that would boost his future scientific career, and will generate also a new DNA-sequencing technology that will impact positively European scientific excellence.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["746635"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Advanced catalyst electrodes from Ionic liquid modified PtNi nanowire arrays for PEFCs"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["IonPEFC"], "Technology_Description": "Recent developments in PEFC research have seen a significant enhancement of catalyst activities and a reduction of cost at a reduced loading of precious metals by employing novel Pt-based extended surface area nanostructures alloyed with transitional metals, but the low stability caused by the easy dissolution of transitional metals in acidic PEFC environment, and the large difficulty to be integrated into devices due to the unconventional morphology of extended surface area nanostructures as Pt/C nanoparticle catalysts limit them mainly to pure material research, resulting in an increasing gap with real high performance devices. ", "To": ["2019-08-02, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-03"], "Project_ID": ["739940"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["QUEEN MARY UNIVERSITY OF LONDON"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Light-addressable potentiometric sensors (LAPS) for zinc imaging with high spatiotemporalresolution for elucidating the role of zinc in age related macular degeneration."], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ZINCLAPS"], "Technology_Description": "Light-addressable potentiometric sensors (LAPS) have great potential as a tool for functional electrochemical imaging of the attachment area of cells, providing information such as ion concentration, extracellular potentials and ion channel activity. The technique is particularly attractive for analysing cell responses of cells with planar polarisation as the cell-surface attachment area is not accessible to conventional electrophysiological measurements. However, current systems suffer either from poor resolution or slow scanning speed. In this project, we propose to develop a novel LAPS setup with high spatiotemporal resolution combined with two-photon fluorescence microscopy that allows imaging of physiological processes with submicron resolution and in real time. Novel zinc sensitive surfaces will be developed and used in conjunction with the new high-resolution and high-speed LAPS setup to investigate the role of zinc in age related macular degeneration (AMD). The retina and the underlying retinal pigment epithelium contain high concentrations of zinc. Several eye disorders are associated with altered zinc balance, and zinc supplementation has become a choice of treatment for diseases like agerelated macular degeneration. Despite its importance in health and diseases of the eye, it is still not well understood how zinc participates in cellular and molecular events and how zinc supplementation might be beneficial. We will investigate zinc fluxes at the basal side of the retinal pigment epithelium where zinc is suspected to play a key role in the formation of deposits and the initiation of AMD. The results of the study may lead to new treatments to prevent, forestall, or reverse the effects of the disease and may also help to elucidate zinc's role in other diseases including type 2 diabetes, pancreatic cancer, and Alzheimer disease and are therefore expected to impact the pharmaceutical industry and increase the quality of life for an ageing population.", "To": ["2019-06-20, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-21"], "Project_ID": ["745820"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM", "KATHOLIEKE UNIVERSITEIT LEUVEN", "IRCCS AZIENDA OSPEDALIERA UNIVERSITARIA SAN MARTINO-IST-ISTITUTO NAZIONALE PER LA RICERCA SUL CANCRO", "THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN", "KLINIKUM DER UNIVERSITAET ZU KOELN", "THE ROYAL VETERINARY COLLEGE", "SURGACOLL TECHNOLOGIES LIMITED", "LIFETEC GROUP BV"], "EU_Contribution": ["EUR 3 607 596,36"], "Project_Title": ["Controlling Cartilage to Bone Transitions for Improved Treatment of Bone Defects and Osteoarthritis"], "Total_Cost": ["EUR 3 607 596,36"], "Country": ["Netherlands", "Belgium", "Italy", "Ireland", "Germany", "United Kingdom", "Ireland", "Netherlands"], "Project_ACR": ["CarBon"], "Technology_Description": "A well-functioning locomotor system is essential for human well-being. This is an important consideration in our aging population with the increased associated costs of ensuring high quality of life. Many people suffer from diseases of the locomotor system, such as bone defects or osteoarthritis, for which current treatments are insufficient. To develop new treatments, CarBon includes 6 academic partners, 3 companies and 3 charitable foundations, working together to train 14 young scientists. We will combine knowledge from the fields of tissue engineering, cartilage and bone developmental biology and pathobiology using skills from the disciplines of cell biology, computational modelling, biotechnology (bioreactors, biomaterials) and drug discovery.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["721432"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["CONSIGLIO NAZIONALE DELLE RICERCHE", "ATHINA-EREVNITIKO KENTRO KAINOTOMIAS STIS TECHNOLOGIES TIS PLIROFOFORIAS, TON EPIKOLNONION KAI TIS GNOSIS", "UNIWERSYTET WARSZAWSKI", "JISC LBG", "UNIVERSITAET BREMEN", "UNIVERSIDADE DO MINHO", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "PIN SOC.CONS. A R.L. - SERVIZI DIDATTICI E SCIENTIFICI PER L UNIVERSITA DI FIRENZE", "INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT", "EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH", "INTERNATIONAL CENTER FOR RESEARCH ON THE ENVIRONMENT AND THE ECONOMY"], "EU_Contribution": ["EUR 1 997 837,50"], "Project_Title": ["OpenAIRE - CONNECTing scientific results in support of Open Science"], "Total_Cost": ["EUR 1 997 837,50"], "Country": ["Italy", "Greece", "Poland", "United Kingdom", "Germany", "Portugal", "France", "Italy", "France", "Switzerland", "Greece"], "Project_ACR": ["OpenAIRE-Connect"], "Technology_Description": "Open Science is around the corner. Scientists and organizations see it as a way to speed up, improve quality and reward, while policy makers see it as a means to optimize cost of science and leverage innovation. Open Science is an emerging vision, a way of thinking, whose challenges always gaze beyond its actual achievements. De facto, today\u2019s scientific communication ecosystem lacks tools and practices to allow researchers to fully embrace Open Science. OpenAIRE-Connect aims to provide technological and social bridges, and deliver services enabling uniform exchange of research artefacts (literature, data, and methods), with semantic links between them, across research communities and content providers in scientific communication. It will introduce and implement the concept of Open Science as a Service (OSaaS) on top of the existing OpenAIRE infrastructure, delivering out-of-the-box, on-demand deployable tools. OpenAIRE-Connect will adopt an end-user driven approach (via the involvement of 5 prominent research communities), and enrich the portfolio of OpenAIRE infrastructure production services with a Research Community Dashboard Service and a Catch-All Notification Broker Service. The first will offer publishing, interlinking, packaging functionalities to enable them to share and re-use their research artifacts (introducing \u201cmethods, e.g. data,software, protocols). This effort, supported by the harvesting and mining \u201cintelligence\u201d of the OpenAIRE infrastructure, will provide communities with the content and tools they need to effectively evaluate and reproduce science. OpenAIRE-Connect will combine dissemination and training with OpenAIRE\u2019s powerful NOAD network engaging research communities and content providers in adopting such services. These combined actions will bring immediate and long-term benefits to scholarly communication stakeholders by affecting the way research results are disseminated, exchanged, evaluated, and re-used.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["EINFRA-22-2016 - User-driven e-infrastructure innovation"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Other", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Other"], "From": ["2017-01-01"], "Project_ID": ["731011"], "Call_for_Proposal": ["H2020-EINFRA-2016-1"]}, -{"Partners": ["UNIVERSITAT DE BARCELONA", "TECHNISCHE UNIVERSITAET BRAUNSCHWEIG", "UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA", "EXPERT YMAGING SL", "AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH", "MEDIZINISCHE UNIVERSITAET WIEN", "FONDATION SUISSE POUR LA RECHERCHEEN MICROTECHNIQUE"], "EU_Contribution": ["EUR 3 759 790"], "Project_Title": ["Overcoming the Limits of Diffraction with Superresolution Lighting on a Chip"], "Total_Cost": ["EUR 3 759 790"], "Country": ["Spain", "Germany", "Italy", "Spain", "Austria", "Austria", "Switzerland"], "Project_ACR": ["ChipScope"], "Technology_Description": "The physical laws of diffraction generally limit the spatial resolution of optical systems, being about 200 nm for light in the visible range. Within ChipScope we want to overcome this limit by developing the scientific and technological basis for a completely new approach to optical superresolution, based on semiconductor nano Light Emitting Diode (nanoLED) arrays with individual pixel operation. The core idea of ChipScope is to use spatially resolved illumination instead of spatially resolved detection for achieving microscopy functionality with superresolution. This will be made possible by developing chip-based nanoLED arrays with light emitting diode (LED) dimensions and distances much smaller than the wavelength of visible light (i.e. <50 nm). Thus, ChipScope will develop the highest resolution LED arrays in the world. These new devices will enable novel science in general and superresolution in particular. Making optical superresolution ubiquitously available is expected to lead to foundational breakthroughs in virtually every field of research and technology that makes use of optical microscopes. Within the project, the first chip-sized \u201cChipScope microscopes\u201d will be developed, tested, calibrated and compared with state-of-the-art microscopy systems. During the course of the project, a game changing real-time imaging device for scientific investigation of living tissue will be used to study the in-cell mechanisms in Chronic Obstructive Pulmonary Disease (COPD) syndrome as a proof-of-concept of the new science and applications that will follow.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-01-2016-2017 - FET-Open research and innovation actions"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2017-01-01"], "Project_ID": ["737089"], "Call_for_Proposal": ["H2020-FETOPEN-1-2016-2017"]}, -{"Partners": ["TEL AVIV UNIVERSITY", "THE UNIVERSITY OF WARWICK", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "UNIVERSITEIT TWENTE", "BERGISCHE UNIVERSITAET WUPPERTAL", "UNIVERSITE DE FRANCHE-COMTE", "UNIVERSITE DE BORDEAUX", "THE UNIVERSITY OF EXETER", "UNIVERSIDAD AUTONOMA DE MADRID", "FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG"], "EU_Contribution": ["EUR 3 932 721,72"], "Project_Title": ["Control of flexible structures and fluid-structure interactions"], "Total_Cost": ["EUR 3 932 721,72"], "Country": ["Israel", "United Kingdom", "United Kingdom", "Netherlands", "Germany", "France", "France", "United Kingdom", "Spain", "Germany"], "Project_ACR": ["ConFlex"], "Technology_Description": "We propose to develop systems and control theory needed to understand and control large flexible structures and fluid structure interactions. The beneficiaries are a group of 15 academics from the fields of modelling, control theory, distributed parameter systems and fluid dynamics, aeroelasticity, swimming and marine engineering, working in either mathematics or engineering departments, with strong links between us. We are located at 10 universities in the UK, France, The Netherlands, Spain, Germany and Israel. In addition, we have four partner universities in Canada, China, USA and France and 11 prestigious industry partners, mostly from Europe. We believe that our backgrounds and skills are sufficiently close so that we can (and do) communicate with ease, but also sufficiently distinct so that we can cover many aspects of this field, and hence (as a consortium) offer outstanding training to young researchers. We believe that this area will have a great impact on the technology of the future, as well as on our understanding of nature, and we are eager to train new scientists and engineers in this broad field. We believe that Science and Technology in Europe will greatly benefit from this research, and from the education and and knowledge that we will impart to a new generation of researchers. Our research plans are organized into five scientific work packages, which cover mathematical systems theory, modelling and model reduction, relevant aspects of control theory, and applications. The applications that we plan to investigate concern a wide range of flexible structures in interaction with fluids: wind turbines, aircraft wings, precision machine tools, vessels linked by cables as encountered in marine salvage operations and microscopic electromechanical devices. These apparently unrelated systems face similar challenges and can be analysed and controlled in a unified framework.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["765579"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["COVENTRY UNIVERSITY", "EIGEN VERMOGEN VAN HET INSTITUUT VOOR LANDBOUW EN VISSERIJONDERZOEK", "LUONNONVARAKESKUS", "UNIVERSITAET FUER BODENKULTUR WIEN", "RIJKSUNIVERSITEIT GRONINGEN", "LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN", "MINISTERIE VAN INFRASTRUCTUUR EN MILIEU"], "EU_Contribution": ["EUR 3 891 072,60"], "Project_Title": ["Building Resourceful and Resilient Communities through Adaptive and Transformative Environmental Practice"], "Total_Cost": ["EUR 3 891 072,60"], "Country": ["United Kingdom", "Belgium", "Finland", "Austria", "Netherlands", "Germany", "Netherlands"], "Project_ACR": ["RECOMS"], "Technology_Description": "RECOMS will train 15 ESRs in transdisciplinary approaches to support resourceful and resilient community environmental practice, tackling societal challenges (e.g. food, energy and climate change), nurturing the potential of stakeholders and vulnerable groupings to create adaptive and transformative sustainability pathways. RECOMS will increase the mobility of ESRs, enhance their Scientific, Professional, Personal and Transferable Skills and impact on their career prospects as researchers, policy makers, facilitators, consultants, change agents, social innovators and environmental educators. The consortium of 7 beneficiaries and 4 partners comprised of public, private and non-profit organisations allows a comparative approach to studying community resourcefulness across a range of (trans) national settings in 6 EU countries. Fundamental is the coupled social-ecological and critical lens to evolutionary resilience thinking, as complex, dynamic and process based, denoting the capacity of a system to change. RECOMS raises capacities to implement practice-based solutions via 15 research projects, divided along 3 interconnected themes: Unlocking and Empowering; Adapting and Transforming; Collaborating and Connecting. RECOMS addresses EU goals of sustainable and inclusive growth and territorial resource-based development, enhancing social cohesion and social innovation. The joint training organised in training events includes integrated action-based learning, collaborative community practice, and experimenting with an assemblage of visual and creative interactive communication techniques. The joint training is complemented by online reflective learning portfolios, local training at hosting institutes, the job-training via secondments and the support of Specialist Practitioner Advisors. RECOMS will impact on varied target groups including communities and policy-makers, and share its outcomes with non-participants via a range of communication and dissemination activities.", "To": ["2022-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2018-03-01"], "Project_ID": ["765389"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["UNIVERSITY STEFAN CEL MARE SUCEAVA", "JOHANNES GUTENBERG-UNIVERSITAT MAINZ", "UNIVERSITAT DE VALENCIA", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "INSTITUTUL DE CHIMIE MACROMOLECULARA PETRU PONI", "UKRORGSYNTEZ", "SRL POLIVALENT-95"], "EU_Contribution": ["EUR 954 000"], "Project_Title": ["Multifunctional Spin Crossover Materials"], "Total_Cost": ["EUR 954 000"], "Country": ["Romania", "Germany", "Spain", "France", "Romania", "Ukraine", "Moldova"], "Project_ACR": ["SPINSWITCH"], "Technology_Description": "This project deals with an exchange programme of seven research teams with the aim to establish and consolidate a network for the design of innovative multifunctional materials based upon iron(II) spin crossover complexes: their synthesis, magnetic and spectroscopic studies, investigations on their crystalline, liquid crystalline and morphological structures, pressure effects on spin crossover properties and, particularly, their implementation into pressure sensors. The synthetic part of this project aims to access novel types of crystalline and liquid crystalline spin crossover complexes, hybrid luminescent materials, photo-switchable liquid crystalline compounds, composites and nano-objects of original morphologies and transition characteristics. These switchable materials will become a matter of different experiments under pressure: magnetic and M\u04e7ssbauer measurements under hydrostatic pressure and optical experiments in a gas pressure cell. This will allow to reach an important impact on the synthesis of new bistable materials, on their behaviour under pressure, and to make them an active part of different pressure sensors. The academic participants involved in this work have collaborated on joint projects and have co-authored several scientific papers. The two industrial institutions have a recognized expertise in organic and material synthesis, commercialization, as well possessing experience on elaboration of spin transition materials. The establishment of this joint exchange programme will promote and strengthen the complementarity of the participants and will stimulate cross-fertilization, thus forming an excellent centre of synergy in research, innovation and technology in the area of functional materials. This network offers a complete training in the synthesis and characterization of new spin crossover materials for various applications.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Romania"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["734322"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["UNIVERSITATEA POLITEHNICA DIN BUCURESTI", "UNIVERSITATEA POLITEHNICA DIN BUCURESTI"], "EU_Contribution": ["EUR 185 925"], "Project_Title": ["Radio wave propagation in heterogeneous media: implications on the electronics of Cosmic Neutrino Detectors"], "Total_Cost": ["EUR 185 925"], "Country": ["Romania", "Romania"], "Project_ACR": ["CosNeD"], "Technology_Description": "Detection of cosmic neutrinos can answer very important questions related to some extremely energetic yet unexplained astrophysical sources such as: compact binary stars, accreting black holes, supernovae etc., key elements in understanding the evolution and fate of the Universe. Moreover, these particles carry the highest", "To": ["2018-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Romania"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-11-01"], "Project_ID": ["714637"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["THE UNIVERSITY OF WARWICK"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Multi-functional DUAL PHOSphorus-based organoCATalysts for stereoselective ring-opening polymerisation"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["DUAL-PHOSCAT"], "Technology_Description": "The stereocontrolled ring-opening polymerisation (ROP) of chiral cyclic esters for the preparation of biodegradable polymers with precise and finely-tuned properties remains a research challenge. Only Few catalysts/initiators have been reported to produce stereoregular high molecular weight polymers; most of them being highly sensitive and/or toxic organometallic species. Organocatalysed ROP produces polymers that are free of residual metal contaminates but to date, does not allow high productivities with high levels of stereocontrol. In this context, the multi-disciplinary proposal DUAL-PHOSCAT proposes to develop chiral tunable dual phosphorus-based organocatalysts to overcome these challenges. For this, a stepwise-synthesis strategy to tailor the organocatalyst architectures and an inventive combinatorial approach using self-assembled oganocatalysts will be investigated. The stepwise synthesis will bind together using chiral linkers, chiral phosphorus-based molecules and chiral thioureas molecules.The self-assembled dual organocatalysts will be obtained combining chiral amine-thioureas and chiral phosphoric acids. These systems will be investigated for the ROP of rac-lactide and rac-beta-butyrolactone. The proposed catalysts enable great advances in the preparation of isotactic polylactide (PLA) stereocomplex and highly tactic poly-3-hydroxybutyrate (PHB) in terms of catalyst stability, productivity, activity and stereoselectivity, in turn making these catalysts efficient green alternative to sensitive and /or toxic organometallic initiators for the synthesis of metal-free highly stereoregular polyesters under industrially-relevant conditions. The PLA and PHB obtained will find potential applications in packaging and fibers (as green alternative to petroleum-based plastics) or as biomedical devices that is in line with the H2020 programme (e.g. Climate action, environment, resource efficiency and raw materials and Health, Demographic and well-being).", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["752405"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["SLOVENSKA ORGANIZACIA PRE VYSKUMNEA VYVOJOVE AKTIVITY ZDRUZENIE", "SLOVENSKA AKADEMIA VIED", "I-EUROPA SRO", "CENTRUM VEDECKO TECHNICKYCH INFORMACII SLOVENSKEJ REPUBLIKY"], "EU_Contribution": ["EUR 248 300"], "Project_Title": ["Festival of Science European Researchers\u00b4 Night 2016 - 2017 in Slovakia"], "Total_Cost": ["EUR 347 700"], "Country": ["Slovakia", "Slovakia", "Slovakia", "Slovakia"], "Project_ACR": ["ERN16-17 SVK"], "Technology_Description": "European Researchers` Night has been successfully implemented 9times and has covered 4 from 8 regions all over Slovakia. In 2015 it took place in 6 cities, the event featured nearly 1.000 researchers and was attended by up to 160.000 visitors. Thanks to interactive presentations of scientific work and research, in very friendly and informal atmosphere, we managed to increase the interest and augmented awareness of science in general public. The main objective is to inform the general public about the inconspicuous, yet fundamental influence of the scientists within the society and to present their outcomes, which are crucial for society. The project supports also the area of regional development and intensifies interaction between hundreds of scientists. The concept for ERN 2016-2017 will have common themes to all venues and locations in Slovakia: Experience the Science (2016) and Science is the story (2017). Active participation of researchers from different institutions, various fields, focusing on various subjects of research will create great platform for showing young people how lively and impulsive could scientific career be. People will have an opportunity to spend all day visiting different presentations and stands, lectures and discussions, testing scientific applications, and getting in touch with real researchers. Thanks to these direct exchanges and discussions they can discover the \"human face\" of researchers and are more likely to remember their successes or stories. In 2016 we intend to prepare exceptional and bigger event in regard to 10th anniversary of ERN in Slovakia as well as the Slovak Presidency of EU Council. Unique celebration of science will be supported by various pre events and teasers and engaged more cultural institutions. Presidency of EU Council will also offer additional space for promoting ERN event as crucial part of enhancing the visibility of the Slovak and EU research.", "To": ["2017-11-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-NIGHT-2016 - European Researchers' Night"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Slovakia"], "Activity": ["Other", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2016-05-01"], "Project_ID": ["723000"], "Call_for_Proposal": ["H2020-MSCA-NIGHT-2016"]}, -{"Partners": ["INSTITUT PASTEUR"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Labeling Flavivirus capsid protein to unravel its dynamics during infection and egress by correlative super-resolution fluorescence and cryo-electron microscopy"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["FLAVIC DYNAMICS"], "Technology_Description": "Vector-borne diseases are major worldwide threats. Specifically, mosquito-borne diseases from the flavivirus genus such as West Nile and dengue viruses are raising major concerns on human health. There are few or no treatment/vaccine strategies to fight these viruses and the relatively poor knowledge of their life cycle (entry and egress) contributes to the deficit in treatment possibilities. A deeper knowledge of the virus cycle is required to unlock the development of antivirals.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["703519"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["INSTITUT PASTEUR"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Interaction between gut-microbiota and the central stress system in cognitive alterations associated with aging."], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["Microbiota and aging"], "Technology_Description": "Aging drives cognitive impairment and general health demise increasing the susceptibility to neurodegenerative disorders in healthy individuals. It is also associated with changes in the gut-microbiota and a general increase in the secretion of stress hormones, known to have debilitating effects when sustained. The gut-microbiota has recently emerged has a crucial modulator of cognitive abilities and general health. Nonetheless, the causes and consequences of the gut-microbiota changes seen in aging are currently unknown. In this application, we propose to study the importance of the age-associated gut-microbiota changes on brain functions, by swapping the gut-microbiota from aged mice into young mice and vice-versa. This will allow knowing the contribution of the gut-microbiota in the cognitive decline and depressive state associated with aging. Furthermore, we will test if the increase in stress hormones known to occur during aging are upstream of those age-associated microbiota changes, by testing the involvement of the amygdala to the hypothalamus-adrenal axis in this phenomena. This will be achieved by using a chemo-genetic approach to control the activation of each component of this pathway. This project will provide the first description of the functional repercussions of the age-associated changes in the gut-microbiota composition on learning and memory deficits and depression, and possibly elucidate one of the upstream mechanisms responsible. The outcome of this work will pave the way toward the elaboration of probiotic treatments against the detrimental effect of aging.", "To": ["2018-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2016-05-01"], "Project_ID": ["708466"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 2 499 761"], "Project_Title": ["Exoribonuclease-mediated degradation of nascent RNA in Malaria Parasites: A Novel Mechanism in Virulence Gene Silencing"], "Total_Cost": ["EUR 2 499 761"], "Country": ["France", "France"], "Project_ACR": ["PlasmoSilencing"], "Technology_Description": "Background: The human protozoan malaria parasite P. falciparum causes approximately 200 million infections and 0.7 million deaths (mainly children) per year. In the well-studied asexual blood stages, cyclic monocistronic gene activation occurs at the transcriptional level; however, relatively few transcription factors have been identified, thus other types of regulatory processes that contribute to this coordinated gene expression are believed to exist. Through the study of molecular process of monoallelic expression of immune evasion genes in P. falciparum (project funded by a previous ERC grant to A. Scherf), we discovered an entirely new mechanism of gene silencing. We demonstrated that an exoribonuclease silences genes linked to severe malaria. A non-canonical 3\u2019-5\u2019exoribonuclease termed PfRNase II destroys nascent RNA made from promoter regions, leading to cryptic unstable mRNA. Parasites carrying a deficient PfRNase II produce full-length mRNA and long noncoding RNA. The molecular events and the number of genes directly controlled by this novel type of posttranscriptional gene silencing remain elusive. ", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2015-11-01"], "Project_ID": ["670301"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["INSTITUT PASTEUR"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Characterization of zebrafish innate lymphoid cells and IL-22"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["ZF-ILC"], "Technology_Description": "The immune system can be subdivided into two main arms: the innate and the adaptive. Recently, it was identified a new family of cells belonging to the innate system but that phenotypically and functionally resemble the specific subtypes of adaptive T lymphocytes. In mice and in humans, these innate lymphoid cells (ILCs) play critical roles in host defense, in shaping the microbiota and in tissue repair at mucosal tissues via secreting cytokines such as IL-22. The innate system is more ancient than the adaptive, however, the existence and diversity of ILCs in organisms other than mammals remains unknown. Also unknown is how ILCs interact with other cells within tissues. This project will address the existence and role of the different subsets of ILCs and the conservation of IL-22 function in a distant relative, the zebrafish, a genetically tractable vertebrate with remarkable optical accessibility. ", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["708128"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6", "CENTRO DE CIENCIAS DO MAR DO ALGARVE", "NATURAL ENVIRONMENT RESEARCH COUNCIL", "THE SCOTTISH ASSOCIATION FOR MARINESCIENCE LBG", "STAZIONE ZOOLOGICA ANTON DOHRN", "MARINE SCOTLAND", "MARINE BIOLOGICAL ASSOCIATION OF THE UNITED KINGDOM", "FORSCHUNGSVERBUND BERLIN EV", "CONSIGLIO NAZIONALE DELLE RICERCHE", "THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS", "TUNATECH GMBH", "XELECT LIMITED", "INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE", "UNIVERSITETET I TROMSOE", "CAB INTERNATIONAL", "UNIVERSITEIT GENT", "INSTITUT PASTEUR", "HELMHOLTZ-ZENTRUM FUER INFEKTIONSFORSCHUNG GMBH", "EUROPEAN MOLECULAR BIOLOGY LABORATORY", "UNIVERSITE DE MARNE LA VALLEE", "TEL AVIV UNIVERSITY", "UNIVERSITE DE NICE SOPHIA ANTIPOLIS", "SCALPRO AS", "LEIBNIZ-INSTITUT DSMZ-DEUTSCHE SAMMLUNG VON MIKROORGANISMEN UND ZELLKULTUREN GMBH*", "HELLENIC CENTRE FOR MARINE RESEARCH", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSITETET I BERGEN"], "EU_Contribution": ["EUR 9 041 611"], "Project_Title": ["European Marine Biological Research Infrastructure Cluster to promote the Blue Bioeconomy"], "Total_Cost": ["EUR 9 041 611"], "Country": ["France", "Portugal", "United Kingdom", "United Kingdom", "Italy", "United Kingdom", "United Kingdom", "Germany", "Italy", "United Kingdom", "Germany", "United Kingdom", "France", "Norway", "United Kingdom", "Belgium", "France", "Germany", "Germany", "France", "Israel", "France", "Norway", "Germany", "Greece", "France", "Norway"], "Project_ACR": ["EMBRIC"], "Technology_Description": "Marine (blue) biotechnology is the key to unlocking the huge economic potential of the unique biodiversity of marine organisms. This potential remains largely underexploited due to lack of connectivity between research services, practical and cultural difficulties in connecting science with industry, and high fragmentation of regional research, development and innovation (RDI) policies. To overcome these barriers, EMBRIC (European Marine Biological Resource Infrastructure Cluster) will link biological and social science research infrastructures (EMBRC, MIRRI, EU-OPENSCREEN, ELIXIR, AQUAEXCEL, RISIS) and will build inter-connectivity along three dimensions: science, industry and regions. The objectives of EMBRIC are to: (1) develop integrated workflows of high quality services for access to biological, analytical and data resources, and deploy common underpinning technologies and practices; (2) strengthen the connection of science with industry by engaging companies and by federating technology transfer (TT) services; (3) defragment RDI policies and involve maritime regions with the construction of EMBRIC. Acceleration of the pace of scientific discovery and innovation from marine bioresources will be achieved through: (i) establishment of multidisciplinary service-oriented technological workflows; (ii) joint development activities focusing on bioprospection for novel marine natural products, and marker-assisted selection in aquaculture; (iii) training and knowledge transfer; (iv) pilot transnational access to cluster facilities and services. EMBRIC will also connect TT officers from contrasted maritime regions to promote greater cohesion in TT practices. It will engage with policy-makers with the aim of consolidating a perennial pan-European virtual infrastructure cluster rooted in the maritime regions of Europe and underpinning the blue bioeconomy.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["INFRADEV-4-2014-2015 - Implementation and operation of cross-cutting services and solutions for clusters of ESFRI and other relevant research infrastructure initiatives"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2015-06-01"], "Project_ID": ["654008"], "Call_for_Proposal": ["H2020-INFRADEV-1-2014-1"]}, -{"Partners": ["INSTITUT PASTEUR"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Dissecting dsRNA uptake in RNAi-based antiviral immunity"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["DDRR"], "Technology_Description": "Important viral infectious diseases, such as dengue and chikungunya, are transmitted to humans by insect vectors. One of the key factors that modulates whether an insect is competent or not to transmit a given pathogen is its innate immune response. The major antiviral defense in insects is the RNA interference (RNAi) mechanism that is activated by the detection of viral double-stranded RNA (dsRNA). During antiviral RNAi a silencing immune signal is transported from one cell to another to set an antiviral state (systemic RNAi). To be primed, non-infected cells must sense this silencing signal and internalize it. Although dsRNA as a mediator of local antiviral immunity is well established in insects, the effectors of a systemic immune response are not identified. For instance, the identification of the dsRNA receptor in insects remains elusive. This proposal intends to dissect the mechanism of dsRNA uptake in insects with special focus on discovering its receptor. I propose to combine functional (genome wide RNAi screen, in vivo dsRNA oral uptake) with binding (electrophoretic mobility shift assay, surface plasmon resonance) and structural assays (expression, production and studies of complexes receptor/dsRNA) using Drosophila melanogaster as insect model and an array of viruses in order to identify and characterize the dsRNA receptor.To be found, the manipulation of this receptor could help control the insect vectors of emerging viral diseases. Understanding how the infection is controlled within the insect before crossover to the human host could generate new strategies to disrupt pathogen transmission.", "To": ["2017-05-31, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2015-06-01"], "Project_ID": ["656398"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["INSTITUT PASTEUR"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Mechanisms of \u03b1-synuclein spreading, implications for synucleinopathies"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["NEUROTUNN"], "Technology_Description": "A common feature of neurodegenerative diseases, including highly prevalent illnesses, is the presence of misfolded protein aggregates in affected regions of the nervous system. Aggregates result from the misfolding of one or more specific proteins, for example, amyloid-\u03b2 in Alzheimer\u2019s disease, \u03b1-synuclein in Parkinson\u2019s disease, and the normal prion protein in transmissible spongiform encephalopathies (TSEs). Recently a series of exciting studies has suggested a prion-like mechanism underlying the pathological spreading of misfolded proteins (mainly tau, \u03b1-synuclein and huntingtin) involved in various neurodegenerative diseases. Particularly striking is the recovery of \u03b1-synuclein aggregates from engrafted embryonic neurons in post-mortem brains transplanted from Parkinson\u2019s patients. Thus, while questioning the therapeutic use of transplants, the understanding of the molecular and cellular fundaments of cell-to-cell transmission of proteinaceous aggregates is clearly in the early stages of investigation and may represent a more readily accessible target for novel disease-modifying therapies, allowing the development of possible common therapeutic strategies. ", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2016-03-01"], "Project_ID": ["702465"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["INSTITUT PASTEUR", "INSTITUT PASTEUR"], "EU_Contribution": ["EUR 1 976 100"], "Project_Title": ["Perivascular cells at the crossroads of inflammation, regeneration and fibrosis"], "Total_Cost": ["EUR 1 976 100"], "Country": ["France", "France"], "Project_ACR": ["PERIF"], "Technology_Description": "The survival of organisms requires the ability to repair tissues upon injury, as well as, after birth, to fight foreign invaders that may have contaminated the wound. This last function is mediated by a complex host response involving immune cells, blood vessels and inflammatory mediators that collectively intend to neutralize the harmful agent and eliminate damaged/necrotic tissue. Initially beneficial, this massive inflammatory response comes with a cost, and adult injured tissues usually heal with a scar, which is an area of fibrous tissue that transiently replaces normal tissue. In chronic settings, scarring can become excessive in a process called fibrosis, to the point of preventing functional recovery of the injured organ and be life threatening. Nearly half of all deaths in industrialized world are due to diseases involving inappropriate, often chronic, inflammatory and fibrotic responses, including lung, kidney and liver diseases, scleroderma, inflammatory bowel diseases, muscular dystrophies, cardiovascular diseases, and tumors. However our current knowledge of the biological processes regulating fibrosis is partial, which has hindered therapeutic advances in the field. Recent data from our team and others drew new attention on a discrete population of mesenchymal cells that wraps around vessels, variously called mural cells, perivascular cells or pericytes, as a major source for profibrotic stromal cells generating scar tissue. Previously known for their vascular protective functions, increasing evidence suggests new and unexpected roles for these cells also in inflammation, repair/regeneration, and cancer. These new findings raise a number of challenging questions relative to their functional diversity, as well as mechanisms of activation/ regulation in disease. The identification and specific targeting of functional subsets of mesenchymal perivascular cells may have notable impact in research and medicine, paving the way for new therapeutic avenues in inflammatory/fibrotic diseases and cancer.", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2015-11-01"], "Project_ID": ["648428"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["INSTITUT PASTEUR", "INSTITUT PASTEUR"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Regulation of cell size and shape in bacteria"], "Total_Cost": ["EUR 1 500 000"], "Country": ["France", "France"], "Project_ACR": ["RCSB"], "Technology_Description": "Proper cell size and shape are important for many biological functions, such as metabolism, signaling, motility, and development. This proposal addresses the fundamental question of how bacteria control their morphology and their cell volume with high precision, using the rod-like bacterium Escherichia coli as a primary model system. Bacterial cell shape is physically determined during growth by the enzymatic expansion and remodeling of the peptidoglycan (PG) cell wall, a partially ordered elastic meshwork that is the pressure-bearing component of the cell envelope. In this proposal we will address two fundamental questions: ", "To": ["2021-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2016-04-01"], "Project_ID": ["679980"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["INSTITUT PASTEUR", "INSTITUT PASTEUR"], "EU_Contribution": ["EUR 1 791 250"], "Project_Title": ["Mechanisms of epigenetic inheritance by short RNAs"], "Total_Cost": ["EUR 1 791 250"], "Country": ["France", "France"], "Project_ACR": ["RNAEPIGEN"], "Technology_Description": "Epigenetic mechanisms are considered to be central to the development of multicellular organisms made of different cell types, all having identical genomes. Similarly, they may explain how genetically identical organisms are capable of adapting to distinct environmental conditions. Yet, the molecular mechanisms regulating how epigenetic traits can be inherited during cell division or across generations are not fully understood. Using the nematode Caenorhabditis elegans, we have recently revealed how the nuclear Argonaute protein CSR-1 and its associated short RNAs participate in global transcriptional regulation and chromatin organization. This unprecedented observation opened up a new class of molecular mechanisms by which Argonaute proteins and their bound short RNAs may actively contribute to epigenetic inheritance in animals.", "To": ["2021-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2016-02-01"], "Project_ID": ["679243"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["UNIVERSITETET I STAVANGER", "HELSINGIN YLIOPISTO", "BOURNEMOUTH UNIVERSITY", "TYOTERVEYSLAITOS", "PROFESSIONSHOJSKOLEN ABSALON S/I", "HOGSKOLEN I MOLDE", "KRIMINALOMSORGSDIREKTORATET", "STICHTING FORENSISCH PSYCHIATRISCHCENTRUM DR. S. VAN MESDAG", "FOOTPRINTS PROJECT"], "EU_Contribution": ["EUR 445 500"], "Project_Title": ["Improving collaborative working between correctional and mental health services"], "Total_Cost": ["EUR 445 500"], "Country": ["Norway", "Finland", "United Kingdom", "Finland", "Denmark", "Norway", "Norway", "Netherlands", "United Kingdom"], "Project_ACR": ["CO-LAB"], "Technology_Description": "Effective collaboration between mental health (MHS) and correctional services (CS) impacts on mental illness and reduces reoffending rates. Service leaders have indicated a need for more effective models of collaboration. Researchers have identified the Change Laboratory Model (CLM) of workplace transformation as a more effective means of supporting interagency collaborative practice than current integration tools. It provides a way to optimise the effectiveness of mental healthcare provision to offenders through a model that fosters innovation and collaborative processes. However, the change laboratory, highly successful internationally and in other clinical contexts, is a new idea in prison development, none as yet being applied to the challenges facing the MHS and CS. The wickedness, complexity and unpredictability of challenges facing interagency working in these secure environments means that piloting the CLM is premature and it must first be adapted to the MHS/CS context. The aim of this study is to validate the change laboratory model ready for implementation in practice. This RISE application builds a community of practice that enriches international research capacity and cooperation to achieve this aim. It brings academic knowledge of the Change Laboratory model to the market of interagency practices between mental health and correctional services for the development of innovation and the advancement of integrated service provision to mentally ill offenders. Knowledge exchange takes place through secondments, interactive workshops, the development of workforce training programmes, study tours, shadowing opportunities and ethnographic research. Through this knowledge exchange, the consortium delivers a user-informed prototype of change laboratory model ready for implementation in the MHS and CS field. This validated change laboratory model, offers the ERA a clear strategy with which to promote integrated care for mentally ill offenders.", "To": ["2021-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Other", "Other"], "From": ["2017-02-01"], "Project_ID": ["734536"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["INSTITUT PASTEUR", "INSTITUT PASTEUR"], "EU_Contribution": ["EUR 1 499 763"], "Project_Title": ["Study of the interplay between CRISPR interference and DNA repair pathways towards the development of novel CRISPR tools"], "Total_Cost": ["EUR 1 499 763"], "Country": ["France", "France"], "Project_ACR": ["CRISPAIR"], "Technology_Description": "CRISPR-Cas loci are the adaptive immune system of archaea and bacteria. They can capture pieces of invading DNA and use this information to degrade target DNA through the action of RNA-guided nucleases. The consequences of DNA cleavage by Cas nucleases, i.e. how breaks are processed and whether they can be repaired, remains to be investigated. A better understanding of the interplay between DNA repair and CRISPR-Cas is critical both to shed light on the evolution and biology of these fascinating systems and for the development of biotechnological tools based on Cas nucleases. CRISPR systems have indeed become a popular tool to edit Eukaryotic genomes. The strategies employed take advantage of different DNA repair pathways to introduce mutations upon DNA cleavage. In bacteria however, the introduction of breaks by Cas nucleases in the chromosome has been described to kill the cell. Preliminary data indicates that this might not always be the case and that some DNA repair pathways could compete with CRISPR immunity allowing cells to survive. Using a combination of bioinformatics and genetics approaches we will investigate the interplay between CRISPR and DNA repair in bacteria with a particular focus on the widely used CRISPR-Cas9 system. The knowledge gained from this study will then help us develop novel tools for bacterial genome engineering. In particular we will introduce a NHEJ pathway in E.coli making it possible to perform CRISPR knockout screens. Finally using CRISPR libraries and multiplexed targeting, we will generate for the first time all combinations of pair-wise gene knockouts in an organism, a task that for now remains elusive, even for large consortiums and with the use of automation. This will enable to decipher genome-scale genetic interaction networks, an important step for our understanding of bacteria as a system.", "To": ["2021-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2016-03-01"], "Project_ID": ["677823"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI PAVIA", "UNIVERSITA DEGLI STUDI DI PAVIA", "INSTITUT PASTEUR"], "EU_Contribution": ["EUR 1 686 875"], "Project_Title": ["Population genomics of co-evolution between non-retroviral RNA viruses and their hosts"], "Total_Cost": ["EUR 1 686 875"], "Country": ["Italy", "Italy", "France"], "Project_ACR": ["NIRV_HOST_INT"], "Technology_Description": "Recent discoveries clearly show that non-retroviral RNA viruses, despite not coding for reverse transcriptase and integrase, can transfer genetic material to their hosts, similarly to DNA viruses and retroviruses. The distribution of non-retroviral integrated RNA viruses (NIRVs) in host populations, mechanisms of NIRVs formation and effects on hosts are unclear. The main objective of this proposal is to uncover the complex biological interactions between non-retroviral RNA viruses and their hosts using the model system \u201cAedes albopictus and Flavivirus\u201d. This system is ideal because Ae. albopictus is a known vector of non-retroviral RNA viruses, including several highly relevant for public health such as dengue viruses (Flaviviridae, Flavivirus) and NIRVs phylogenetically related to Flaviviruses have been identified in its genome. First, a population genomic approach will be used to interrogate the genome of Ae. albopictus from different geographic populations at their DNA and RNA levels. This approach will permit the systematic characterization of the distributions of NIRVs in natural host populations, the analyses of correlations between the presence of NIRVs and viral infections and the description of NIRVs genomic context, from which insights on mechanisms of NIRVs formation can be derived. Secondly, tissue-specificity of the NIRVs, their trans-generational stability and impact on mosquito biology will be analysed in a controlled laboratory environment. Somatic integrations could contribute to acquired immunity to their respective viruses or establishment of persistent viral infection. Germ-line integrations could have an evolutionary impact. If NIRVs affect Ae. albopictus vector competence or the genome of emerging viral populations, they could be manipulated for vector control purposes. Additionally, results on NIRV distribution in natural host populations and mechanisms of NIRVs formation will have implications in medicine because several non-retroviral RNA viruses are emerging as delivery systems for gene therapy applications.", "To": ["2021-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2016-05-01"], "Project_ID": ["682394"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["INSTITUT PASTEUR", "INSTITUT PASTEUR"], "EU_Contribution": ["EUR 1 498 955"], "Project_Title": ["New and mature neurons in adult circuits: telling memories apart"], "Total_Cost": ["EUR 1 498 955"], "Country": ["France", "France"], "Project_ACR": ["NEWRON"], "Technology_Description": "How does the brain distinguish between memories that closely resemble each other? The hippocampal dentate gyrus has been suggested to serve this purpose by generating non-overlapping memory representations in a process termed \u201cpattern separation\u201d. Intriguingly, during adult life, the dentate gyrus is constantly supplied with new neurons, providing new circuit elements that can incorporate into the neuronal network. How the activity of new adult-born neurons and mature granule cells combines to drive the production and storage of distinct memories represents a new frontier in understanding brain function. However, to determine how these neurons transform similar synaptic input patterns into decorrelated spike output patterns representing distinct memories, we need to monitor and manipulate their subthreshold and suprathreshold activity during behaviour.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2016-10-01"], "Project_ID": ["678790"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["INSTITUT PASTEUR"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Genetics of Alternative Transcript Abundance upon immune Cellular Activation"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["GATTACA"], "Technology_Description": "The human body is constantly exposed to infectious agents. Efficient immune response is therefore fundamental to protect the cells from infection and keep individuals healthy. Still, extreme variations are observed in the efficiency of immune response among individuals and populations. Recently, the dissection of the genetic bases of the host immune response to infection has fostered a large interest in the scientific community. As a result, there is now a growing understanding of the influence of genetic variation on the transcriptional reprogramming of immune cells during infection. However, it is now widely accepted that the underlying \u2018one gene\u2013one protein\u2019 paradigm is overly simplistic and cannot account for the full complexity of the transcriptome. Here, we propose to study how genetic variants affect transcript diversity to modulate the response to pathogens at the individual and population levels. To do so, we will seek to identify genetic variants that have conferred a selective advantage to human populations through modulation of isoforms usage in response to infection. This work will rely on an innovative strategy that combines coexpression-based studies of the isoform regulatory networks with analysis of the genetic determinants of splicing in response to infection. In doing so, this study should improve our understanding of isoform regulation and identify novel regulatory elements and splicing factor-target relationships in the specific context of infection.", "To": ["2017-09-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2015-10-01"], "Project_ID": ["655417"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["INSTITUT PASTEUR"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Glucose metabolism and mTOR pathway role in CD8+ T cell control of HIV-1"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["GLUTORHIV"], "Technology_Description": "Antiretroviral therapy can decrease HIV-1 below the limit of detection but fails to eliminate the virus completely. One of the main goals of a HIV-1 vaccine is the generation of cytotoxic CD8 T cell responses that counteract the virus. CD8 T cells participate in the control of viremia early but progressively show weakened functions, which leads to loss of virus control. HIV controllers are a rare group of infected patients who can control the virus for years without antiretroviral therapy. CD8 T cells from HIV-controllers display an outstanding capacity to eliminate infected CD4 T cells ex vivo but the underlying mechanisms are still not understood.", "To": ["2018-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2016-04-01"], "Project_ID": ["706871"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["INSTITUT PASTEUR", "INSTITUT PASTEUR"], "EU_Contribution": ["EUR 2 750 000"], "Project_Title": ["Microbial invasion and dissemination within the host, mechanisms and effects"], "Total_Cost": ["EUR 2 750 000"], "Country": ["France", "France"], "Project_ACR": ["INVADIS"], "Technology_Description": "An infection is defined by the deleterious consequences of the interactions between a pathogen and a host. Thus, studying the biology of infection reveals critical properties of hosts and pathogens, and is a way forward to address basic biological questions and improve health.", "To": ["2021-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2016-11-01"], "Project_ID": ["681829"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["INSTITUT PASTEUR", "INSTITUT PASTEUR"], "EU_Contribution": ["EUR 1 147 500"], "Project_Title": ["Bacterial, cellular and epigenetic factors that control enteropathogenicity"], "Total_Cost": ["EUR 1 147 500"], "Country": ["France", "France"], "Project_ACR": ["BacCellEpi"], "Technology_Description": "Understanding the establishment and persistence of bacterial infections in the gut requires integrating an ensemble of factors including bacterial and host components and the presence of other microorganisms. We will capitalize on 25 years of studies on the bacterium Listeria monocytogenes used as a model, to focus on three objectives which will significantly increase our knowledge of the bacterium, of the cell biology of infection and of the epigenetic reprogramming upon infection. ", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2015-10-01"], "Project_ID": ["670823"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["UNIVERSITEIT UTRECHT", "TECHNISCHE UNIVERSITAET DRESDEN", "INSTITUT CURIE", "THE FRANCIS CRICK INSTITUTE LIMITED", "CARDIFF UNIVERSITY", "UNIVERSITY COLLEGE LONDON", "INSTITUT PASTEUR", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSITAET BASEL"], "EU_Contribution": ["EUR 3 935 968,56"], "Project_Title": ["Principles of Polarity \u2013 Integrating genetic, biophysical and computational approaches to understand cell and tissue polarity"], "Total_Cost": ["EUR 3 935 968,56"], "Country": ["Netherlands", "Germany", "France", "United Kingdom", "United Kingdom", "United Kingdom", "France", "France", "Switzerland"], "Project_ACR": ["PolarNet"], "Technology_Description": "The ability of cells to polarize underlies the most basic biological functions such as motility and response to external challenges, but also the formation and maintenance of tissues in a multicellular organism. The importance of cell polarity is underscored by the fact that cell polarity is essential for animal development and is perturbed in disease states such as cancer. Understanding cell polarity requires knowledge of the molecular players involved and a quantitative description of their biochemical interactions, as well as the mechanical processes underlying polarity establishment. PolarNet brings together academic and private partners from 7 European countries to establish a multidisciplinary, intersectoral training and research programme that will study the basic principles of cell polarity. The research will combine complementary model systems ranging from fungi and cultured mammalian cells to whole organisms, and employ a broad set of approaches such as advanced genetics, protein biochemistry, high-resolution live imaging and image analysis, biophysics and theoretical modelling. This setting provides an opportunity to train early stage researchers in a unique combination of experimental and theoretical approaches. This will provide an excellent starting point for a successful career in the rapidly expanding field of multidisciplinary or \u2018integrative\u2019 biology. Training Europe\u2019s next generation of scientists at the forefront of cell and organismal polarity research is crucial for progress in several medically important fields, including cancer research and stem cell biology. The tight collaboration with non-academic partners will strengthen the technological base of different projects and provide early stage researchers with insights into the translation potential of the performed studies and the career development opportunities in biomedical industry.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["675407"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["SKA ORGANISATION", "NATIONAL RESEARCH FOUNDATION", "COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION"], "EU_Contribution": ["EUR 4 955 475"], "Project_Title": ["Square Kilometre Array: Infrastructure Detailed Design for SKA Phase 1"], "Total_Cost": ["EUR 4 955 475"], "Country": ["United Kingdom", "South Africa", "Australia"], "Project_ACR": ["IN-SKA"], "Technology_Description": "The Square Kilometre Array (SKA) is an international project to construct the largest and most sensitive radio telescope ever conceived. The SKA will use hundreds of thousands of radio telescopes receivers, in three unique configurations, which will enable astronomers to monitor the sky in unprecedented detail and survey the entire sky thousands of times faster than any system currently in existence. The SKA telescopes will be co-located in Africa and in Australia. South Africa\u2019s Karoo desert will cover the core of the high and mid frequencies of the radio spectrum which will have telescopes spread all over the continent, with Australia\u2019s Murchison region covering the low frequency range and hosting the survey instrument. The objective of the IN-SKA proposal is to support the implementation of the SKA, enabling the start of construction in 2018 and delivery of first science around 2020. To achieve this, the proposal plans to provide resources to complete the Detailed Design of the core SKA Infrastructure required in South Africa and Australia. The proposed programme will address the design of roads and civil works, power distribution to run the telescope and supporting computing facilities, antenna foundations and the specialist design of new buildings; buildings that will be suitable for maintaining a pristine radio-quiet environment needed to ensure that SKA is able to achieve its science goals. In addition to driving innovation in many areas, and supporting the SKA as an inspirational vehicle for skills, industry and outreach, the ultimate deliverables of tender documentation ready for construction will place European and other national industry in leading positions to benefit directly from implementation of the SKA in 2018.", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["INFRADEV-3-2015 - Individual implementation and operation of ESFRI projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations"], "From": ["2016-01-01"], "Project_ID": ["676621"], "Call_for_Proposal": ["H2020-INFRADEV-1-2015-1"]}, -{"Partners": ["INSTITUT PASTEUR", "INSTITUT PASTEUR"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Common mechanisms of host membrane trafficking subversion by intracellular pathogens to rupture bacterial containing vacuoles"], "Total_Cost": ["EUR 2 000 000"], "Country": ["France", "France"], "Project_ACR": ["EndoSubvert"], "Technology_Description": "A common strategy of bacterial pathogens is active or passive uptake into host cells. There, they can localize within a bacterial containing vacuole (BCV) or access the host cytoplasm through BCV rupture. Hence, intracellular pathogens are often classified as vacuole-bound or cytoplasmic. Recently, this definition has been challenged by the discovery that many vacuole-bound pathogens, including Mycobacterium tuberculosis and Salmonella enterica, access the host cytoplasm, and by the insight that cytoplasmic bacteria, like Shigella flexneri or Listeria monocytogenes, do not always escape the BCV. Despite this increasing complexity, a precise understanding lacks for why and how a pathogen \u201cchooses\u201d between a BCV or the cytoplasm and yet this is very important: because of differential pathogen sensing in membrane-bound and cytoplasmic compartments, intracellular localization leads to induction of different host responses. Therefore, a comprehensive understanding of the processes controlling BCV integrity is not only essential, but can provide new therapeutic targets. Our previous research has implemented innovative fluorescence microscopy to track the invasion steps of pathogenic bacteria. We have further integrated a large-volume, correlative, light/electron microscopy (CLEM) workflow via focused ion beam scanning electron microscopy. This uncovered the subversion of host Rab cascades by Shigella to rupture its BCV. Starting with the Shigella model of epithelial cell invasion, we will delineate the precise molecular mechanisms controlling BCV integrity in different host cell types. We will analyze (i) the scaffolds of host pathways for membrane remodeling, (ii) their subversion by various pathogens, and (iii) their differential regulation depending on pathophysiological conditions. Together, this will allow development of novel, rational antimicrobial strategies and will yield fundamental insight into understudied cell biological mechanisms of membrane trafficking.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-01-01"], "Project_ID": ["682809"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH", "PHILIPPS UNIVERSITAET MARBURG", "RIJKSUNIVERSITEIT GRONINGEN", "UPPSALA UNIVERSITET", "INSTITUT PASTEUR", "UNIWERSYTET JAGIELLONSKI", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "Novartis Pharma AG", "RIDGEVIEW INSTRUMENTS AB", "ASTRAZENECA AB", "GIOTTO BIOTECH"], "EU_Contribution": ["EUR 3 836 995,92"], "Project_Title": ["Accelerated Early staGe drug diScovery"], "Total_Cost": ["EUR 3 836 995,92"], "Country": ["Germany", "Germany", "Netherlands", "Sweden", "France", "Poland", "Switzerland", "Switzerland", "Sweden", "Sweden", "Italy"], "Project_ACR": ["AEGIS"], "Technology_Description": "The development of effective novel drugs - especially for rare and neglected diseases - is one of the biggest challenges of the upcoming decades, as illustrated by the recent Ebola outbreak. Moreover, European innovation in new drug registrations is dramatically falling behind compared to the US and Asia.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-01-01"], "Project_ID": ["675555"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["INSTITUT PASTEUR", "INSTITUT PASTEUR", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 499 726"], "Project_Title": ["Reconstituting Autophagosome Biogenesis in vitro"], "Total_Cost": ["EUR 1 499 726"], "Country": ["France", "France", "Germany"], "Project_ACR": ["Autophagy in vitro"], "Technology_Description": "Autophagy is a catabolic pathway that delivers cytoplasmic material to lysosomes for degradation. Under vegetative conditions, the pathway serves as quality control system, specifically targeting damaged or superfluous organelles and protein-aggregates. Cytotoxic stresses and starvation, however, induces the formation of larger autophagosomes that capture cargo unselectively. Autophagosomes are being generated from a cup-shaped precursor membrane, the isolation membrane, which expands to engulf cytoplasmic components. Sealing of this structure gives rise to the double-membrane surrounded autophagosomes. Two interconnected ubiquitin (Ub)-like conjugation systems coordinate the expansion of autophagosomes by conjugating the autophagy related (Atg)-protein Atg8 to the isolation membrane. In an effort to unravel the function of Atg8, we reconstituted the system on model membranes in vitro and found that Atg8 forms together with the Atg12\u2013Atg5-Atg16 complex a membrane scaffold which is required for productive autophagy in yeast. Humans possess seven Atg8-homologs and two mutually exclusive Atg16-variants. Here, we propose to investigate the function of the human Ub-like conjugation system using a fully reconstituted in vitro system. The spatiotemporal organization of recombinant fluorescent-labeled proteins with synthetic model membranes will be investigated using confocal and TIRF-microscopy. Structural information will be obtained by atomic force and electron microscopy. Mechanistic insights, obtained from the in vitro work, will be tested in vivo in cultured human cells. We belief that revealing 1) the function of the human Ub-like conjugation system in autophagy, 2) the functional differences of Atg8-homologs and the two Atg16-variants Atg16L1 and TECPR1 and 3) how Atg16L1 coordinates non-canonical autophagy will provide essential insights into the pathophysiology of cancer, neurodegenerative, and autoimmune diseases.", "To": ["2020-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2015-04-01"], "Project_ID": ["638603"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["INSTITUT PASTEUR"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Making a yeast-based candidate vaccine against Porcine Epidemic Diarrhea Virus (PEDV)"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["PIGYVAX"], "Technology_Description": "PIGYVAX aims to create pig vaccine candidates against PEDV, a pathogen of swine causing significant challenges to the swine industry globally. This project will utilize yeast-based vaccine carrying nanoparticles of measles ribonucleoprotein (RNP) fused with PEDV spike protein (S1). The multimerization of monomeric S1 antigen through RNP will increase immunogenicity due to better recognition of antigen presenting cells. As the yeast delivery system has strong auto-adjuvant properties, the vaccine does not require complementation with accessory adjuvant, which reduces the cost of vaccine production. Moreover, P. pastoris yeast, commonly present on fruits, is a certified safe microorganism for animal feeds rendering it a most practical and convenient way to deliver vaccines to large-scale farms. Therefore, we aim to use this vaccine platform to express S1 antigen of PEDV and deliver it orally to stimulate a protective immune response against PEDV in sows, which will be passively transferred to fully protect piglets from succumbing to the disease. In this project, Dr. Phanramphoei Frantz will utilize her knowledge on pathogenesis of PEDV and the yeast-RNP platform while gaining expertise on vaccine study and development from the host institute. This will initiate a successful collaboration project between Institut Pasteur and BIOTEC (Thailand) to where the experienced researcher will return after the project.", "To": ["2018-06-12, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2016-06-13"], "Project_ID": ["707128"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET", "SAROMICS BIOSTRUCTURES AB", "ENAMINE LIMITED LIABILITY COMPANY,RESEARCH AND PRODUCTION ENTERPRISE"], "EU_Contribution": ["EUR 1 286 630,94"], "Project_Title": ["Selective Agonists For Serotonin Receptors"], "Total_Cost": ["EUR 1 286 630,94"], "Country": ["Denmark", "Sweden", "Ukraine"], "Project_ACR": ["SAFER"], "Technology_Description": "SAFER will train 5 ESRs, PhD students, to obtain ample scientific, business and transferrable skills, arming them with the expertise to translate knowledge into products and services with importance for European industry and society. All ESRs will first train together at one university to develop complementary skills and basic research data; and subsequently move to two SMEs for applied and commercial research. ", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-09-01"], "Project_ID": ["765657"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["THE UNIVERSITY OF NOTTINGHAM", "HELSINGIN YLIOPISTO", "NIZO FOOD RESEARCH BV", "UNIVERSIDADE NOVA DE LISBOA", "INSTITUTO DE TECNOLOGIA QUIMICA E BIOLOGICA - UNIVERSIDADE NOVA DE LISBOA", "PURAC BIOCHEM BV", "INSTITUT PASTEUR", "Green Biologics Ltd.", "STICHTING WAGENINGEN RESEARCH"], "EU_Contribution": ["EUR 3 910 777,56"], "Project_Title": ["UNDERSTANDING THE CLOSTRIDIUM SPORE, A PREREQUISTE FOR DISEASE INTERVENTIONS AND EXPLOITATION"], "Total_Cost": ["EUR 3 910 777,56"], "Country": ["United Kingdom", "Finland", "Netherlands", "Portugal", "Portugal", "Netherlands", "France", "United Kingdom", "Netherlands"], "Project_ACR": ["CLOSPORE"], "Technology_Description": "Bacterial endospores are the most resistant life-forms on earth and the most important single feature of the genus Clostridium. Thus, whilst the pathogenesis of its notorious pathogens (C. botulinum, C. perfringens and C. difficile) is ascribed to the devastating toxins produced (neurotoxins, endotoxins and cytotoxins), it is their capacity to produce spores that lies at the heart of the diseases they cause. This is because spores play the pivotal role in the spread of infection (eg, C. difficile) and in foodstuff contamination and food poisoning (eg, C. botulinum and C. perfringens). The processes of spore formation (sporulation) and germination (return of the dormant spore to toxin-producing, vegetative cells), therefore, represent key intervention points. On the other hand, the majority of clostridia are entirely benign and can sustainably produce all manner of useful chemicals and fuels. Crucially, the regulation of chemical production is intimately linked to that of sporulation. Spores of benign species may also be used as a delivery system for treating cancer. Yet, despite the spore\u2019s importance, little is known of the developmental processes of sporulation and germination. This is because research and training efforts on Clostridium spores are fragmented and there is no coherence between researchers working on pathogenic and industrially important species. CLOSPORE will address this deficiency by pooling the resources of Europe\u2019s leading universities, research organisations and companies, to create an intersectorial Research and Training Programme that is multi-facetted, interdisciplinary and focused on clostridial spores. Accordingly, CLOSPORE will produce the innovative, applied research leaders of the future, able to tackle the big societal challenges facing Europe and the world.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations"], "From": ["2015-01-01"], "Project_ID": ["642068"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["INSTITUT PASTEUR"], "EU_Contribution": ["EUR 2 354 400"], "Project_Title": ["Institut Pasteur International Docotal Program"], "Total_Cost": ["EUR 4 708 800"], "Country": ["France"], "Project_ACR": ["PASTEURDOC"], "Technology_Description": "PASTEURDOC is an advanced educational and research program, hosted by the Institut Pasteur in Paris. Its goal is to train junior investigators possessing medical and/or scientific educational backgrounds to become future leaders in academic education and research institutions, international organizations, private companies, or administration. PASTEURDOC is intended to co-fund and advance the already well-established and very successful Pasteur Paris University International Doctoral Program, in operation since 2009 in partnership with three renowned Parisian universities. PASTEURDOC will enhance the host capacity to train young researchers, while strengthening the Marie Sk\u0142odowska-Curie Actions recommendations for professional development of early-stage researchers. ", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2014-DP - Marie Sk\u0142odowska-Curie Co-funding of regional, national and international programmes (COFUND-DP)"], "Funding_scheme": ["MSCA-COFUND-DP - Doctoral programmes"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2015-10-01"], "Project_ID": ["665807"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2014"]}, -{"Partners": ["STICHTING VUMC", "OTICON A/S", "THE UNIVERSITY OF NOTTINGHAM"], "EU_Contribution": ["EUR 1 637 488,08"], "Project_Title": ["HEAR-ECO Innovative Hearing Aid Research - Ecological Conditions and Outcome Measures"], "Total_Cost": ["EUR 1 637 488,08"], "Country": ["Netherlands", "Denmark", "United Kingdom"], "Project_ACR": ["HEAR-ECO"], "Technology_Description": "In today\u2019s ageing European population, hearing impairment is an increasing concern for public health and societal participation. The percentage of hearing-impaired people will rise from around 16% of the adult EU population now to around 40% in 2030. Hearing aid (HA) fitting is the most widely prescribed solution for hearing impairment. However, only around 30%-40% of adults with hearing impairment use HAs in daily life. One of the reasons for this is that methods used to develop and evaluate HAs are still not based on conditions in which HAs are actually used. Thus the potential of improved HA technology to meet the needs of individual users in their daily lives is acutely under-exploited. The science in HEAR-ECO will help to facilitate the paradigm shift which is needed to bridge the gap. Such a paradigm shift requires a new generation of hearing scientists that are able to integrate conventional Audiology with Motivational and Social psychology (motivation to listen, cognition), Psychophysiology (pupillometry, PEP, EEG), and HA technology. HEAR-ECO will train six ESRs capable of spanning these disciplines and translating their knowledge into innovative technological HA evaluation and development. The six ESRs will be trained through local training at academic partners in The Netherlands and the UK and secondment to one of the largest hearing aid manufacturers in the world in Denmark \u2013 and through network wide training, including an associated partner in Liverpool. The ESRs will be capable of developing and combining new tools and outcome measures for realistic everyday communication and translating this to innovative technological HA evaluation and development.", "To": ["2021-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["765329"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA", "KOBENHAVNS UNIVERSITET", "UNIVERSITY COLLEGE LONDON", "FORSCHUNGSVERBUND BERLIN EV", "HELLENIC CENTRE FOR MARINE RESEARCH", "ISPA CRL"], "EU_Contribution": ["EUR 3 950 859,24"], "Project_Title": ["INternational training at the Science-Policy Interface for Researchers in Europe, for Nature"], "Total_Cost": ["EUR 3 950 859,24"], "Country": ["France", "Italy", "Denmark", "United Kingdom", "Germany", "Greece", "Portugal"], "Project_ACR": ["Inspire4Nature"], "Technology_Description": "The growing recognition that biological diversity is a global asset of tremendous value to present and future generations has underpinned a number of multilateral environmental policy agreements, including the EU Biodiversity Strategy to 2020. Implementing these agreements requires a global-scale cooperation among conservation scientists to collect, mobilise and synthesise biodiversity data and ecological knowledge, and translating them directly into recommendations for conservation action and indicators of progress towards meeting internationally agreed goals and targets. Inspire4Nature\u2019s purpose is to contribute to the formation of a new generation of creative, entrepreneurial and innovative early-stage researchers by providing them with both research-related and transferable skills which will enable them to work at this science-policy interface, converting their knowledge and ideas into tools for tackling complex global environmental problems. To do so, we propose an ambitious training programme combining individual research projects (leading to PhD degrees) of a high scientific standard strategically positioned at the science-policy interface in biodiversity conservation with a rich network-wide training programme including training events and joint projects that will provide the ESRs with a wide diversity of scientific, communication and project management skills. The Consortium\u2019s strength comes from an unprecedented collaboration between academic and non-academic conservation organisations that will generate in the European research area a unique focus of professional training at the interface between conservation science and policy.", "To": ["2022-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["766417"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["KATHOLIEKE UNIVERSITEIT LEUVEN", "KOBENHAVNS UNIVERSITET", "INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE", "DOHLER GMBH", "CARGILL R&D CENTRE EUROPE"], "EU_Contribution": ["EUR 3 437 311,68"], "Project_Title": ["Enginomics in food quality design: the case of shelf-stable fruit-, vegetable- and legume-based foods"], "Total_Cost": ["EUR 3 437 311,68"], "Country": ["Belgium", "Denmark", "France", "Germany", "Belgium"], "Project_ACR": ["FOODENGINE"], "Technology_Description": "The overarching objective of FOODENGINE is to provide, for the first time, a research-based training programme to a new generation of young food scientists and technologists by introducing an enginomics approach in food quality design. It connects an omics approach to instrumentally quantify food quality with an advanced engineering approach using multi-response kinetics to model food quality changes during processing and storage. At the same time, FOODENGINE will develop models linking the enginomics-based instrumental food quality design with sensory properties, consumer acceptability and consumer preferences to create new products appealing to consumers. FOODENGINE provides unique interdisciplinary, international and intersectoral training opportunities to 13 ESRs, each for 36 months. This extensive international (5 countries), intersectoral (2 universities, 1 research institute and 6 food (ingredient) companies) and interdisciplinary (food engineering, food chemistry, food nutrition and sensory/consumer research) training should lead for all ESRs to a PhD degree. FOODENGINE will boost the career perspectives of the FOODENGINE fellows to the top level. In addition, it has the ambition to become a best-practise example for structuring PhD research training in food science and technology at the European level. Although FOODENGINE specifically focusses on sustainable commodities which are essential parts of a healthy lifestyle (fruit-, vegetable-, legume-based food ingredients and foods), the skills and new ways of thinking the fellows will acquire are generic and can be extrapolated beyond the specific application area (diverse range of food systems or food processes) in their future careers.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-01-01"], "Project_ID": ["765415"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA", "TECHNISCHE UNIVERSITAET WIEN", "UNIVERSITA DEGLI STUDI DI PERUGIA", "THE UNIVERSITY OF NOTTINGHAM", "UNIVERSIDAD DE CANTABRIA", "INSTITUT FRANCAIS DES SCIENCES ET TECHNOLOGIES DES TRANSPORTS, DE L'AMENAGEMENT ET DES RESEAUX", "COVENTRY UNIVERSITY", "UNIVERSITY COLLEGE LONDON", "LANCASTER UNIVERSITY", "UNIVERSITAET INNSBRUCK", "CELU EKSPERTS", "DURTH ROOS CONSULTING GMBH", "SOCIETA' AZIONARIA PRODOTTI ASFALTICO BITUMINOSI AFFINI - S.A.P.A.B.A. S.P.A."], "EU_Contribution": ["EUR 3 878 868,96"], "Project_Title": ["Sustainable, Accessible, Safe, Resilient and Smart Urban Pavements"], "Total_Cost": ["EUR 3 878 868,96"], "Country": ["Italy", "Austria", "Italy", "United Kingdom", "Spain", "France", "United Kingdom", "United Kingdom", "United Kingdom", "Austria", "Latvia", "Germany", "Italy"], "Project_ACR": ["SAFERUP"], "Technology_Description": "Urban pavements comprise almost 40% of European cities and are the main means by which people travel every day. Urban pavements must accommodate all users in the most efficient, safe, sustainable and smart way. A key factor to increase the liveability of tomorrow\u2019s Smart cities will be transforming the way urban pavements are perceived, designed, built, maintained and function. SAFERUP! aims to provide cities with innovative solutions that will form the future urban paved environment, by training talented researchers in the fields of: smart, recycled and durable paving materials; provision for vulnerable users (e.g. elderly & disabled) accessibility and protection; studying user behaviour; life cycle analysis; wash-off water management and bioremediation; tempered and acoustic pavements; energy harvesting and self-sensing technologies. The SAFERUP! Consortium believes in this future and has created a unique team of world leading commercial and academic research engineers and scientists, with the diverse range of expertise needed to develop the novel solutions required to deliver this future and its anticipated benefits. Fifteen ESRs will undertake their PhDs in a research and training programme designed to optimise their multidisciplinary and cross-sectoral experience through secondments and a variety of SAFERUP!-wide fora. All ESRs\u2019 projects are interrelated and considerable synergies, trans-project contributions and collaborations will occur. A key focus of the training will be career planning, entrepreneurship and skills development in particular communication. SAFERUP! participants with communication expertise will develop the communication and dissemination strategy to maximise the exploitation of the developed solutions. SAFERUP! will create a new generation of professionals with multidisciplinary expertise in urban pavements and allied fields appealing to employers, who will expand the social benefits of the new urban pavements well beyond the end of SAFERUP!", "To": ["2022-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-03-01"], "Project_ID": ["765057"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON", "UNIVERZITA KARLOVA", "UNIWERSYTET JAGIELLONSKI", "BUDAPESTI CORVINUS EGYETEM", "TARTU ULIKOOL", "UNIVERZITET U BEOGRADU"], "EU_Contribution": ["EUR 3 508 841,16"], "Project_Title": ["Delayed Transformational Fatigue in Central and Eastern Europe"], "Total_Cost": ["EUR 3 508 841,16"], "Country": ["United Kingdom", "Czech Republic", "Poland", "Hungary", "Estonia", "Serbia"], "Project_ACR": ["FATIGUE"], "Technology_Description": "The aim of FATIGUE is to develop theoretically and empirically robust explanations for the causes and consequences of rise of illiberalism and authoritarianism in post-communist Europe (and Europe, more generally) with reference to the concept of 'delayed transformational fatigue'. The project will seek to answer the following questions:", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["765224"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["RIJKSUNIVERSITEIT GRONINGEN", "AALBORG UNIVERSITET", "THE UNIVERSITY OF EDINBURGH", "EUROPA-UNIVERSITAT FLENSBURG", "UNIVERSITETET I STAVANGER", "CHALMERS TEKNISKA HOEGSKOLA AB"], "EU_Contribution": ["EUR 4 067 521,56"], "Project_Title": ["Energy Systems in Transition"], "Total_Cost": ["EUR 4 067 521,56"], "Country": ["Netherlands", "Denmark", "United Kingdom", "Germany", "Norway", "Sweden"], "Project_ACR": ["ENSYSTRA"], "Technology_Description": "To facilitate the necessary energy transition, there is an urgent need for highly trained professionals with the scientific knowledge and professional skills to analyse, understand and design relevant (new) energy systems and governance in different sectors and administration. The proposed project Energy Systems in Transition (ENSYSTRA) aims to train 15 ESRs in this field. The objectives of ENSYSTRA are 1) to develop state-of-the-art science of energy systems transition, scenario analysis and energy modelling tools with emphasis on interdisciplinary model collaboration, 2) to provide ESRs with interdisciplinary, inter-sectoral and applied perspectives on the energy transition, 3) to provide new skills and competences for interdisciplinary analysis, 3) to establish collaboration between key universities and their networks, 4) to create and increase linkages between different academic disciplines, applied research, industry and the public sector, 5) develop links and synergies between relevant scientific arenas, and 6) to contribute to accessible energy science based on open source work environments. By focussing on a prominent \u2018\u2019living lab\u2019\u2019 of the energy transition, the North Sea region, the project will bring together a strong network and analytical capacity to understand energy system & scenario modeling; new energy technologies & infrastructures; actor behavior & interactions; and policy & market design, linking the regional to the international scale. Through a carefully designed training programme, ESRs are trained in both scientific and transferable skills with ample opportunity to collaborate between different projects and partners. The total effort will result in major progress in the field of energy system analysis and transition modelling. By the combined use and improvement of a range of modelling tools and methods, the project will deliver integral insights in energy transition pathways, policy implications and options for the North Sea region.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["765515"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH", "Bruker HTS GmbH", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "CONSIGLIO NAZIONALE DELLE RICERCHE", "Columbus Superconductors SpA", "HELMHOLTZ-ZENTRUM BERLIN FUR MATERIALIEN UND ENERGIE GMBH", "I-CUBE RESEARCH", "ISTITUTO NAZIONALE DI FISICA NUCLEARE", "TECHNISCHE UNIVERSITAET DRESDEN", "TECHNISCHE UNIVERSITAET WIEN", "UNIVERSITAET SIEGEN", "UNIVERSITAET STUTTGART", "WIRTSCHAFTSUNIVERSITAT WIEN"], "EU_Contribution": ["EUR 3 841 922,16"], "Project_Title": ["European Advanced Superconductivity Innovation and Training"], "Total_Cost": ["EUR 3 841 922,16"], "Country": ["Switzerland", "Germany", "France", "Italy", "Italy", "Germany", "France", "Italy", "Germany", "Austria", "Germany", "Germany", "Austria"], "Project_ACR": ["EASITrain"], "Technology_Description": "The two greatest obstacles to a wide spread adoption of superconductivity remain the limited understanding of its fundamental principles and the yet insufficient capability for large-scale, cost-effective deployment of the technology. Science rather than serendipity is the key to unlock the potentials of this alluring natural phenomenon. The proposed ITN integrates sound research projects aimed at learning to predict the behaviour of superconducting materials, at introducing innovative manufacturing techniques, at developing efficient cryogenic refrigeration techniques as key enablers for future applications and establishing these technologies as the new state of the art. The ambitious goals of this consortium are (1) making advanced superconductors fitter for the market, (2) assessing their innovation capacities and (3) equipping a new generation of researchers with the unique skills required to convert knowledge into products: Efficient grid power management, 21st century medical imaging, leaps in effectiveness of wind power generators, efficient electric propulsion systems and sustainable refrigeration for industry give an impression of the potential societal benefits that superconductor-based technologies can catalyze. This initiative under European leadership federates leading universities, research centres and industries, embracing a variety of science sectors, such as physics and mathematics, material sciences, process and mechanical engineering, refrigeration, cryogenics and innovation management. The intriguing blend of science and engineering, compounded by visionary application opportunities in companies, creates a fertile environment for innovative training of early-stage researchers. Significant training lead-times call for a dedicated action. This ITN will provide its fellows with a sound knowledge in the relevant fields along with business competences and prepare them for a broad spectrum of career opportunities in research and industry.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Switzerland"], "Activity": ["Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["764879"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["UNIVERSITE CATHOLIQUE DE LOUVAIN", "FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS", "DSM Ahead BV", "UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II.", "DANMARKS TEKNISKE UNIVERSITET", "JOHANNES GUTENBERG-UNIVERSITAT MAINZ", "ECOLE SUPERIEURE DE PHYSIQUE ET DECHIMIE INDUSTRIELLES DE LA VILLE DEPARIS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 3 340 690,20"], "Project_Title": ["Double Dynamics for design of new responsive polymer networks and gels"], "Total_Cost": ["EUR 3 340 690,20"], "Country": ["Belgium", "Greece", "Netherlands", "Italy", "Denmark", "Germany", "France", "France"], "Project_ACR": ["DoDyNet"], "Technology_Description": "Polymeric gels and networks are ubiquitous in daily life (foodstuff, cosmetics) and high-added value applications (tissue engineering, adhesives, coating, drug release, portable batteries, additive manufacturing). They can be either permanent (covalently crosslinked) and resist flow, or physical (reversible) and easy to process while creeping at long times. The grand challenge is to efficiently combine and control within the same material, distinct features of these two classes of networks, such as large mechanical strength, deformability, swelling and self-healing, in order to create multiply responsive materials for new applications.", "To": ["2021-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2017-11-01"], "Project_ID": ["765811"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG", "KUNGLIGA TEKNISKA HOEGSKOLAN", "LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN", "SCUOLA NORMALE SUPERIORE", "SYDDANSK UNIVERSITET", "ECOLE NATIONALE SUPERIEURE DE CHIMIE DE PARIS", "NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU", "DANMARKS TEKNISKE UNIVERSITET"], "EU_Contribution": ["EUR 3 745 978,92"], "Project_Title": ["Training network for COmputational Spectroscopy In Natural sciences and Engineering"], "Total_Cost": ["EUR 3 745 978,92"], "Country": ["Germany", "Sweden", "Germany", "Italy", "Denmark", "France", "Norway", "Denmark"], "Project_ACR": ["COSINE"], "Technology_Description": "During the last two decades, ab-initio Quantum Chemistry has become an important scientific pillar in chemical research. For electronic ground states, well established theoretical research tools exist, that can be applied by scientists in order to guide experimental interpretation and synthesis design. For optical properties and excited electronic states, dominated by electron correlation, computational tools are lagging behind and are currently missing the accuracy needed in order to have predictive power. However, such tools are urgently required for the fundamental understanding of natural photo-initiated processes as well as organic optical devices.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["765739"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["UNIVERSITE DE LIMOGES", "AKADEMIA GORNICZO-HUTNICZA IM. STANISLAWA STASZICA W KRAKOWIE", "RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN", "MONTANUNIVERSITAT LEOBEN", "UNIVERSITE D'ORLEANS", "UNIVERSIDADE DO MINHO"], "EU_Contribution": ["EUR 3 737 239,56"], "Project_Title": ["Advanced THermomechanical mOdelling of Refractory linings"], "Total_Cost": ["EUR 3 737 239,56"], "Country": ["France", "Poland", "Germany", "Austria", "France", "Portugal"], "Project_ACR": ["ATHOR"], "Technology_Description": "Refractories are heat-resistant materials used as inner linings of high temperature furnaces, reactors and processing units. ATHOR (Advanced THermomechanical multiscale mOdelling of Refractory linings) is an innovative, collaborative and interdisciplinary project that brings together 6 academic beneficiaries and 8 private partners. The main objective is to develop high-end engineering technologies in material engineering and numerical simulations thanks to an intensive cooperation between academia, raw materials suppliers, refractory producers and end-users. Starting from material characterization, all significant properties will be investigated, including fracture behaviour, tension and compression creep behaviour, corrosion and thermal shock resistance. The interdisciplinary aspects will be addressed thanks to a multiscale approach looking at the influences of micro-, meso- and macro-characteristics on each other. To conduct their research and interlink the different topics, the 15 recruited researchers will take advantage of the most sophisticated numerical tools to model, design and predict the life of different lining configurations in critical operation conditions.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["764987"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["INSTITUT PASTEUR"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Uncovering the role of cis genetic elements in antigenic variation of Plasmodium falciparum using the CRISPR-Cas9 genome editing technology"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["REACT"], "Technology_Description": "Malaria is an infectious human disease caused by parasitic protozoans of the Plasmodium type. P. falciparum causes the most lethal form with about 400.000 deaths annually. Pathogenesis involves expression of clonally variant molecules encoded by multi gene families at the surface of the infected host cells (erythrocyte). The most important virulence factor is called PfEMP1, which undergoes antigenic variation and is encoded by 60 var gene members. Despite the major scientific efforts, the molecular mechanisms orchestrating antigenic variation are still elusive. The reason is the lack of tools to perform genome editing in the natural epigenetic context, which is crucial in this important immune escape process.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["741447"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["INSTITUT PASTEUR"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Metabolic characterization of ILCs under homeostatic or stress conditions."], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["ILMET"], "Technology_Description": "Innate lymphoid cells (ILCs) are the most recently identified components of the innate immune system. ILCs colonize mainly mucosa-associated tissues and they have a crucial role in metabolic homeostasis, and defense against infections and cancer. ILCs are highly plastic and they rapidly shape their functional output in response to local environmental cues. Two ILC subsets (ILC2 and NK cells) have been respectively implicated in the maintenance of adipose tissue homeostasis and in the development of chronic inflammation in obese patients. It has been shown that cellular metabolism affects the development and function of adaptive lymphocytes. In contrast, very little is known about innate lymphocytes metabolic requirements under homeostatic conditions and how they metabolically adapt to environmental perturbations.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["746828"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["INSTITUT PASTEUR"], "EU_Contribution": ["EUR 264 668,40"], "Project_Title": ["Elucidating the role of m6A RNA methylation on the replication and pathogenesis of influenza A virus."], "Total_Cost": ["EUR 264 668,40"], "Country": ["France"], "Project_ACR": ["IAV-m6A"], "Technology_Description": "It has recently become apparent that post-transcriptional editing of mRNA by methylation of adenosines (m6A) plays a key role in regulating gene expression. In particular, total loss of m6A editing blocks the development of early embryos in a number of organisms. However, how m6A modifications, which are added in the nucleus and primarily detected by 3 cytoplasmic \u201creader\u201d proteins, exert their effects remains unknown. The presence of m6A on viral transcripts has been known for 40 years, yet has only recently been shown to enhance HIV-1 gene expression and replication. Influenza A virus (IAV) that, like HIV-1, replicates in the nucleus, is known to bear a high level of m6A on viral RNA. However, whether and how m6A editing affects IAV replication remains unknown. Here, the researcher proposes the investigation of the role of m6A in IAV pathogenesis. The main objectives of this proposal are; to compile a precise map of m6A sites on IAV-PR8 RNA, determine their functional significance on replication and RNA trafficking, assess how m6A machinery is altered in IAV infected cells, and evaluate the conservation of these sites across additional pathogenic IAV strains.", "To": ["2020-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2017-06-01"], "Project_ID": ["747810"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["INSTITUT PASTEUR", "BACMINE SL", "SWANSEA UNIVERSITY"], "EU_Contribution": ["EUR 900 000"], "Project_Title": ["SustainAble Farming for Effective Aquaculture"], "Total_Cost": ["EUR 900 000"], "Country": ["France", "Spain", "United Kingdom"], "Project_ACR": ["SAFE-Aqua"], "Technology_Description": "Aquaculture is an important food source for the world\u2019s growing population. The increasing demand and productivity of aquaculture leads to global trade in breeding stock, genetic material and aquaculture products for human consumption, but also exacerbates the globalization of pathogens.SAFE-Aqua, an international inter- and multidisciplinary consortium, aims to provide scientific solutions to solve disease-related issues in aquaculture using shrimp as a model through research and innovation staff exchange and sharing of knowledge and ideas from research to market. SAFE-Aqua will explore the benefits of developed feed additives on keeping a healthy gut microbial balance, enhancing immune-capacity, and maintaining nutritional integrity of shrimp as a product. To assess these beneficial effects, SAFE-Aqua will synergize the cutting-edge technology platforms, multidisciplinary and complementary expertise, as well as infrastructure from networks of the partnership among the leading research institutes in France, UK and Thailand and a synthetic biology company in Spain. ", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["734486"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["UNIVERSITE DE MONTPELLIER", "UNIVERSITEIT LEIDEN", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "SLOVENSKA TECHNICKA UNIVERZITA V BRATISLAVE", "FUNDACIO INSTITUT DE CIENCIES FOTONIQUES", "INSTITUT PASTEUR", "THE MANCHESTER METROPOLITAN UNIVERSITY", "ACQUIFER AG", "TATRAMED SOFTWARE SRO", "PHASEVIEW"], "EU_Contribution": ["EUR 3 562 028,64"], "Project_Title": ["Training European Experts in Multilevel Bioimaging, Analysis and Modelling of Vertebrate Development and Disease"], "Total_Cost": ["EUR 3 562 028,64"], "Country": ["France", "Netherlands", "France", "United Kingdom", "Slovakia", "Spain", "France", "United Kingdom", "Germany", "Slovakia", "France"], "Project_ACR": ["ImageInLife"], "Technology_Description": "This proposal sprang from European scientists in both academia and industry who identified a common challenge: setting up a training frame to educate the next generation of imagers in complex biological systems (healthy & pathological), so they are able to master all major aspects of this competitive field and bring important innovations to universities and companies.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["721537"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["INFRAFRONTIER GMBH", "HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH", "USTAV MOLEKULARNI GENETIKY AKADEMIE VED CESKE REPUBLIKY VEREJNA VYZKUMNA INSTITUCE", "OULUN YLIOPISTO", "CENTRE EUROPEEN DE RECHERCHE EN BIOLOGIE ET MEDECINE", "BIOMEDICAL SCIENCES RESEARCH CENTER ALEXANDER FLEMING", "VETERINAERMEDIZINISCHE UNIVERSITAET WIEN", "Toronto Centre for Phenogenomics Inc.", "EUROPEAN MOLECULAR BIOLOGY LABORATORY", "HELMHOLTZ-ZENTRUM FUER INFEKTIONSFORSCHUNG GMBH", "MEDIZINISCHE HOCHSCHULE HANNOVER", "TSE SYSTEMS GMBH", "AYOXXA BIOSYSTEMS GMBH", "KOBENHAVNS UNIVERSITET", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "UNIVERSITAT AUTONOMA DE BARCELONA", "INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "INSTITUT PASTEUR", "Biomedcode Hellas SA", "TEL AVIV UNIVERSITY", "CONSIGLIO NAZIONALE DELLE RICERCHE", "STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS", "ACADEMISCH ZIEKENHUIS GRONINGEN", "FUNDACAO CALOUSTE GULBENKIAN", "KAROLINSKA INSTITUTET", "MEDICAL RESEARCH COUNCIL", "GENOME RESEARCH LIMITED", "THE UNIVERSITY OF SHEFFIELD"], "EU_Contribution": ["EUR 4 955 877,16"], "Project_Title": ["Towards enduring mouse resources and services advancing research into human health and disease"], "Total_Cost": ["EUR 4 968 252,16"], "Country": ["Germany", "Germany", "Czech Republic", "Finland", "France", "Greece", "Austria", "Canada", "Germany", "Germany", "Germany", "Germany", "Germany", "Denmark", "Spain", "Spain", "France", "France", "France", "Greece", "Israel", "Italy", "Netherlands", "Netherlands", "Portugal", "Sweden", "United Kingdom", "United Kingdom", "United Kingdom"], "Project_ACR": ["INFRAFRONTIER2020"], "Technology_Description": "The INFRAFRONTIER RI integrates European Mouse Clinics and the European Mouse Mutant Archive with the common goal to ensure access to mouse models for basic research of human health and disease, and to translate this knowledge into therapeutic approaches for the benefit of the European society. ", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["INFRADEV-03-2016-2017 - Individual support to ESFRI and other world-class research infrastructures"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Germany"], "Activity": ["Other", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["730879"], "Call_for_Proposal": ["H2020-INFRADEV-2016-1"]}, -{"Partners": ["INSTITUT PASTEUR", "INSTITUT PASTEUR"], "EU_Contribution": ["EUR 1 675 746"], "Project_Title": ["Development, maintenance and functions of Resident Macrophages."], "Total_Cost": ["EUR 1 675 746"], "Country": ["France", "France"], "Project_ACR": ["ResidentMacroPhage"], "Technology_Description": "Macrophages are professional phagocytic cells that orchestrate homeostatic and innate immune functions, via the scavenging of cells, debris, and pathogens, and the production of cytokines, both concurring to tissue homeostasis and repair. This project aims to investigate in vivo the development and functions of macrophages, which have considerable phenotypic and functional diversity depending on their tissue of residence and pathophysiological conditions. Because this diversity is not well understood, the functions of macrophages in vivo have not been well characterized. Most hematopoietic cells renew from hematopoietic stem cells (HSC), however recent evidence has shown that tissue \u2018resident\u2019 macrophages are generated from yolk sac progenitors, expand and differentiate within developing seeded tissues, and self-maintain in adults independently of HSC. In contrast to HSC-derived macrophages, resident macrophages proliferate locally in steady state and might self-renew. Thus, two lineages of macrophages coexist in most adult tissues. To critically assess the contribution of resident macrophages to tissue repair/regeneration, this proposal aims to determine their developmental pathway and the underlying molecular mechanisms that control their renewal and functions in vivo. This project will investigate the control of differentiation and proliferation in the resident macrophage lineage by combining state-of-the-art genetic fate-mapping approaches with innovative live-imaging in mice. We will develop novel methodologies to visualize the interactions between cell cycle and differentiation, to identify the molecular control of macrophage proliferation and to decipher their specific role during regeneration. This work will significantly increase our knowledge of the differentiation, proliferation and function of resident macrophages in development and tissue repair and will open new venues of research into the role of self-renewing macrophages in regeneration and aging.", "To": ["2021-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2016-12-01"], "Project_ID": ["715230"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["NOFIMA AS", "UNIVERSITA DEGLI STUDI DI FIRENZE", "WAGENINGEN UNIVERSITY", "INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE", "AARHUS UNIVERSITET", "CENTRE DE RECHERCHE DE L INSTITUT PAUL BOCUSE", "UNIVERSIDAD DE LA REPUBLICA"], "EU_Contribution": ["EUR 2 933 056,80"], "Project_Title": ["BRINGING DOWN BARRIERS TO CHILDREN\u2019S HEALTHY EATING"], "Total_Cost": ["EUR 2 933 056,80"], "Country": ["Norway", "Italy", "Netherlands", "France", "Denmark", "France", "Uruguay"], "Project_ACR": ["Edulia"], "Technology_Description": "Edulia responds to the urgent need of EU society to find new ways to tackle the escalating issue of obesity, through promoting healthier eating from childhood. Based on the relations of sensory perception, pleasure, food choice and food behaviour, the project will look for new approaches to drive children to like and actively choose healthy foods, developing healthier habits. Edulia is a multi-disciplinary and inter-sectorial European Training and Research Network with a global reach. Our network will train a new generation of innovative and adaptable researchers, with highly specialised skills across complementary fields studying children\u2019s food choice, while exposing them to cross-sector experiences, in order to build strong career development paths. The training program includes multidisciplinary scientific training within natural and social sciences, secondments in academic and non-academic organisations, and courses in transferable skills, promoting science communication and outreach. The overall aim of the research programme is to better understand how multiple factors act as barriers for children\u2019s healthy eating and how to tackle them, bringing together leading scientists in the Food Choice arena in a collaborative network that will transcend the limits of this project and strengthen European research. Edulia will go further than the classical approach of \u201cteaching children what is healthy\u201d, by exploring approaches such as positive marketing, nudging strategies, focusing on peer and family social interactions, studying sensory and non-sensory parameters that influence what is eaten (food choice) and how much is eaten (intake), and exploiting the positive food sensory characteristics which can drive healthy eating through enhancing pleasure. We will ultimately propose innovative approaches to support children\u2019s healthier eating, providing a strong knowledge base and clear guidance for children, the general public, the food industry and EU policy makers.", "To": ["2022-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Norway"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["764985"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["AUDEERING GMBH", "AUDEERING GMBH"], "EU_Contribution": ["EUR 149 937,50"], "Project_Title": ["Voice Emotion detection by Appraisal Inference"], "Total_Cost": ["EUR 149 937,50"], "Country": ["Germany", "Germany"], "Project_ACR": ["VocEmoApI"], "Technology_Description": "The automated sensing of human emotions has gained a lot of commercial attention lately. For facial and physiological sensing many companies offer first professional products. Recently, voice analytics has become a hot topic, too, with first companies emerging for the telecom, entertainment, and robot markets (e.g. Sympalog, Aldebaran, etc.). Current vocal emotion detection approaches rely on machine learning where emotions are identified based on a reference set of expression clips. The drawback of this method is the need to rely on a small set of basic, highly prototypical emotions. Real life emotion detection application fields such as clinical diagnosis, marketing research, media impact analysis, and forensics and security, require subtle differentiations of feeling states. VocEmoApI will develop a first-of-its-kind proof-of-concept software for vocal emotion detection based on a fundamentally different approach: Focusing on vocal nonverbal behavior and sophisticated acoustic voice analysis, it will exploit the building blocks of emotional processes. This approach will infer not only basic emotion categories but also much finer distinctions such as subcategories of emotion families and subtle emotions. The development of VocEmoApI draw\u2019s extensively on the results of the applicant\u2019s Advanced Grant, providing a solid theoretical basis. Market analysis through marketing research partners will be conducted and the prototype software will be utilized to promote the technology and estimate a product value based on feedback from industry contacts. Strong impact of VocEmoApI on large markets such as household robotics, public security, clinical diagnosis and therapy, call analytics, and marketing research can expected.", "To": ["2017-04-30, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2015 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Germany"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-11-01"], "Project_ID": ["680883"], "Call_for_Proposal": ["ERC-2015-PoC"]}, -{"Partners": ["RIJKSUNIVERSITEIT GRONINGEN"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["Aptamer nanostructures dual-targeted to the HER receptor family for cancer therapy"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["ADHERE"], "Technology_Description": "The proposed research programme deals with the development of aptamer nanostructures for targeted cancer therapy. Immunotherapy encompasses a growing field of anti-cancer therapeutics that target cancer cells expressing specific antigens, such as members of the HER receptor. Currently, immunoglobulins directed to HER1, better known as EGFR, and HER2 are used in the clinical management of several types of cancer. There are, however, several disadvantages associated with the production and application of immunoglobulins. Moreover, there is evidence that dual-targeting of multiple receptors at the same time is advantageous for improving clinical outcome and reducing drug resistance. Aptamers, which are short single-stranded oligonucleotides that can bind a target molecule in a similar fashion as immunoglobulins, may form, due to their physicochemical properties, a superior alternative strategy for targeted cancer therapy. In ADHERE, I will design (WP1) and investigate in vitro (WP2) and in vivo (WP3) the use of aptamer nanostructures with bispecific (against both EGFR and HER2) and multivalent (up to 4 binding ligands) targeting properties for cancer cell targeting.", "To": ["2018-02-28, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["707229"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITAET HAMBURG", "UNIVERSITY OF PLYMOUTH", "FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA", "THE UNIVERSITY OF HERTFORDSHIRE HIGHER EDUCATION CORPORATION", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.", "DANIELI TELEROBOT LABS S.R.L."], "EU_Contribution": ["EUR 3 106 495,20"], "Project_Title": ["Safety Enables Cooperation in Uncertain Robotic Environments"], "Total_Cost": ["EUR 3 106 495,20"], "Country": ["Germany", "United Kingdom", "Italy", "United Kingdom", "Germany", "Italy"], "Project_ACR": ["SECURE"], "Technology_Description": "The majority of existing robots in industry are pre-programmed robots working in safety zones, with visual or auditory warning signals and little concept of intelligent safety awareness necessary for dynamic and unpredictable human or domestic environments. In the future, novel cognitive robotic companions will be developed, ranging from service robots to humanoid robots, which should be able to learn from users and adapt to open dynamic contexts. The development of such robot companions will lead to new challenges for human-robot cooperation and safety, going well beyond the current state of the art. Therefore, the SECURE project aims to train a new generation of researchers on safe cognitive robot concepts for human work and living spaces on the most advanced humanoid robot platforms available in Europe. The fellows will be trained through an innovative concept of project-based learning and constructivist learning in supervised peer networks where they will gain experience from an intersectoral programme involving universities, research institutes, large and SME companies from public and private sectors. The training domain will integrate multidisciplinary concepts from the fields of cognitive human-robot interaction, computer science and intelligent robotics where a new approach of integrating principles of embodiment, situation and interaction will be pursued to address future challenges for safe human-robot environments.", "To": ["2019-08-31, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Chiara Andreoli", "Tel.: +3901071781854", "Fax: +39 010 7170817", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-09-01"], "Project_ID": ["642667"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["INSTITUT PASTEUR", "INSTITUT PASTEUR"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["RNA virus attenuation by altering mutational robustness"], "Total_Cost": ["EUR 150 000"], "Country": ["France", "France"], "Project_ACR": ["1toStopVax"], "Technology_Description": "RNA viruses have extreme mutation frequencies. When a RNA virus replicates, nucleotide mutations are generated resulting in a population of variants. This genetic diversity creates a cloud of mutations that are potentially beneficial to viral survival, but the majority of mutations are detrimental to the virus. By increasing the mutation rate of a RNA virus, viral fitness is reduced because it generates more errors, and attenuates the virus during in vivo infection. Another feature that affects RNA virus fitness is mutational robustness. Mutational robustness is the ability to buffer the negative effects of mutation. ", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2016-09-01"], "Project_ID": ["727758"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["TEL AVIV UNIVERSITY", "TEL AVIV UNIVERSITY"], "EU_Contribution": ["EUR 1 696 888"], "Project_Title": ["Understanding Deep Face Recognition"], "Total_Cost": ["EUR 1 696 888"], "Country": ["Israel", "Israel"], "Project_ACR": ["DeepFace"], "Technology_Description": "Face recognition is a fascinating domain: no other domain seems to present as much value when analysing casual photos; it is one of the few domains in machine learning in which millions of classes are routinely learned; and the trade-off between subtle inter-identity variations and pronounced intra-identity variations forms a unique challenge. ", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["725974"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V."], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Development of a Microwave Assisted Cell Disruption of Biomass and Extraction of Valuable Compounds"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["Amicrex"], "Technology_Description": "The combination of biomass valorisation, process intensification and green technology is an attractive research challenge for the European Community being in line with the \u201cResource-efficient Europe\u201d flagship initiatives by optimizing the use of material, energy resources and gaining valuable products with lower impact on our environment and health. The AMICREX project accepts this challenge and aims to develop an integrated process design for future industrial implementation, where by-products from agro industrial processes (e.g. carrot peels) can be valorised by recovering high- value nonpolar components (e.g. carotenoids, well recognized natural pigments and widely used in the food and cosmetic industries) through a microwave intensified microemulsion extraction process. The AMICREX concept can be extended to address the challenges proposed by extraction of nonpolar metabolites, especially carotenoids, from other renewable biomass sources (e.g. Microalgae). The key aspects of the proposed technology are 1) avoid the use of hazardous organic solvents in nonpolar compounds\u2019 extraction by using microemulsion as extraction media, and 2) improve extraction kinetics by microwave cell disruption method in order to liberate intracellular compounds and make them available for the subsequent extraction process.", "To": ["2018-09-09, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations"], "From": ["2015-05-01"], "Project_ID": ["661198"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["TTY-SAATIO", "MITTUNIVERSITETET", "UNIVERSITAT DE VALENCIA", "UNIVERSITY OF NEWCASTLE UPON TYNE", "CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.", "HOLOGRAFIKA HOLOGRAMELOALLITO FEJLESZTO ES FORGALMAZO KFT", "RAYTRIX GMBH"], "EU_Contribution": ["EUR 3 801 840,48"], "Project_Title": ["European Training Network on Full Parallax Imaging"], "Total_Cost": ["EUR 3 801 840,48"], "Country": ["Finland", "Sweden", "Spain", "United Kingdom", "Germany", "Germany", "Hungary", "Germany"], "Project_ACR": ["ETN-FPI"], "Technology_Description": "Current displays fall far short of truly recreating visual reality. This can never be achieved by painting an image on a flat surface such as a TV screen, but requires a full-parallax display which can recreate the complete lightfield, i.e. the light traveling in every direction through every point in space. Recent years have seen major developments towards this goal, promising a new generation of ultra-realistic displays with applications in medicine, informatics, manufacturing, entertainment, gaming and more. However, achieving this will require a new generation of researchers trained both in the relevant physics, and in the biology of human vision. The European Training Network on Full-Parallax Imaging (ETN-FPI) aims at developing this new generation. The research concept of the network is to depart from the notations of plenoptics, light field and integral imaging, used sometimes interchangeably, and to harmonize and advance further the research in these areas under the umbrella of the wider and viewer-centred FPI concept. Fifteen early-stage researchers will be employed on novel inter-disciplinary FPI projects. The training disciplines include theoretical and applied optics, multi-dimensional image processing, and visual neuroscience. The targeted applications range from plenoptic microscopy to interaction with visual content generated by wide field-of-view displays. Extensive studies on perception of continuous parallax and subjective tests on various displays are planned. The training program includes local training, online seminars, workshops, training schools and a conference. The researchers trained within the network are expected to gather competitive skills and become highly competent in bringing innovations to the field of ultra-realistic and interactive visual media. This will enhance their employability in a rapidly growing sector in academia and industry and position Europe as a leader in this emerging multidisciplinary field.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-10-01"], "Project_ID": ["676401"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["UNIVERSIDADE DO PORTO", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "EFACEC ENGENHARIA E SISTEMAS SA", "GREATCELL SOLAR UK LIMITED", "INSTYTUT CHEMII FIZYCZNEJ POLSKIEJ AKADEMII NAUK", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSITAET ULM"], "EU_Contribution": ["EUR 2 993 403,50"], "Project_Title": ["New technological advances for the third generation of Solar cells"], "Total_Cost": ["EUR 2 993 403,75"], "Country": ["Portugal", "Switzerland", "Portugal", "United Kingdom", "Poland", "France", "Germany"], "Project_ACR": ["GOTSolar"], "Technology_Description": "It is believed that solid-state perovskite solar cells (PSCs) will be the next generation of power source, contributing for fostering the use of photovoltaics in buildings\u2019 roofs and facades. Actually, their transparency, various possibilities of colors and high kWh/nominal power ratio offer to PSCs an opportunity to conquer markets that are not attainable by traditional silicon solar cells. To turn this ambition to a marketable product several efforts are still needed and this project aims to give relevant answers to those key challenges.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-1-2014 - FET-Open research projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Portugal"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["687008"], "Call_for_Proposal": ["H2020-FETOPEN-2014-2015-RIA"]}, -{"Partners": ["FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS", "KARLSRUHER INSTITUT FUER TECHNOLOGIE", "COVESTRO DEUTSCHLAND AG", "AVANZARE INNOVACION TECNOLOGICA SL", "GVS S.P.A.", "UNIVERSIDADE DO MINHO", "UNIVERSITEIT TWENTE", "PROMOLDING BV"], "EU_Contribution": ["EUR 3 794 898,96"], "Project_Title": ["European Training Network to Accelerate the Development Chain of Nanostructured Polymers"], "Total_Cost": ["EUR 3 794 898,96"], "Country": ["Germany", "United Kingdom", "Greece", "Germany", "Germany", "Spain", "Italy", "Portugal", "Netherlands", "Netherlands"], "Project_ACR": ["TheLink"], "Technology_Description": "Research and training in TheLink spans the material development chain for nanostructured polymers. These materials, including phase separated polymers and composites, are attracting scientific and industrial interest due to the outstanding properties and functionalities that can be achieved. However, to exploit the potential of these materials an in-depth understanding of the relationship between nano/micro structures and macro-level properties is required.", "To": ["2018-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2014-11-01"], "Project_ID": ["642890"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["STICHTING EGI", "OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN", "VLAAMS INSTITUUT VOOR DE ZEE VZW", "INSTITUTE OF INFORMATION AND COMMUNICATION TECHNOLOGIES", "SWISS NATIONAL GRID ASSOCIATION (SWING)", "CESNET ZAJMOVE SDRUZENI PRAVNICKYCH OSOB", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.", "GESELLSCHAFT FUR WISSENSCHAFTLICHE DATENVERARBEITUNG MBH GOTTINGEN", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "CSC-TIETEEN TIETOTEKNIIKAN KESKUS OY", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE", "ETHNIKO DIKTYO EREVNAS TECHNOLOGIAS AE", "SVEUCILISTE U ZAGREBU SVEUCILISNI RACUNSKI CENTAR", "MAGYAR TUDOMANYOS AKADEMIA SZAMITASTECHNIKAI ES AUTOMATIZALASI KUTATOINTEZET", "ISTITUTO NAZIONALE DI FISICA NUCLEARE", "CONSORZIO INTERUNIVERSITARIO RISONANZE MAGNETICHE DI METALLO PROTEINE", "PROVINCIA LOMBARDO VENETA - ORDINEOSPEDALIERO DI SAN GIOVANNI DI DIO- FATEBENEFRATELLI", "CONSIGLIO NAZIONALE DELLE RICERCHE", "ENGINEERING - INGEGNERIA INFORMATICA SPA", "SURFSARA BV", "AKADEMIA GORNICZO-HUTNICZA IM. STANISLAWA STASZICA W KRAKOWIE", "LABORATORIO DE INSTRUMENTACAO E FISICA EXPERIMENTAL DE PARTICULAS", "ICETA INSTITUTO DE CIENCIAS, TECNOLOGIAS E AGROAMBIENTE DA UNIVERSIDADE DO PORTO", "UPPSALA UNIVERSITET", "USTAV INFORMATIKY, SLOVENSKA AKADEMIA VIED", "TURKIYE BILIMSEL VE TEKNOLOJIK ARASTIRMA KURUMU", "SCIENCE AND TECHNOLOGY FACILITIES COUNCIL", "BIOBANKS AND BIOMOLECULAR RESOURCES RESEARCH INFRASTRUCTURE CONSORTIUM (BBMRI-ERIC)", "EUROPEAN MOLECULAR BIOLOGY LABORATORY", "EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH", "EISCAT SCIENTIFIC ASSOCIATION", "FOOD AND AGRICULTURE ORGANIZATION OF THE UNITED NATIONS FAO", "AGROKNOW IKE", "MAAT France", "THE TRUSTEES OF INDIANA UNIVERSITY", "ACADEMIA SINICA", "ADVANCED SCIENCE AND TECHNOLOGY INSTITUTE", "INSTITUT TEKNOLOGI BANDUNG", "UNIVERSITI PUTRA MALAYSIA"], "EU_Contribution": ["EUR 8 000 000"], "Project_Title": ["Engaging the EGI Community towards an Open Science Commons"], "Total_Cost": ["EUR 8 650 001,50"], "Country": ["Netherlands", "Austria", "Belgium", "Bulgaria", "Switzerland", "Czech Republic", "Germany", "Germany", "Spain", "Finland", "France", "France", "Greece", "Croatia", "Hungary", "Italy", "Italy", "Italy", "Italy", "Italy", "Netherlands", "Poland", "Portugal", "Portugal", "Sweden", "Slovakia", "Turkey", "United Kingdom", "Austria", "Germany", "Switzerland", "Sweden", "Italy", "Greece", "France", "United States", "Taiwan", "Philippines", "Indonesia", "Malaysia"], "Project_ACR": ["EGI-Engage"], "Technology_Description": "Over the last decade, the European Grid Infrastructure (EGI) has built a distributed computing and data infrastructure to support over 21,000 researchers from many disciplines with unprecedented data analysis capabilities. EGI builds on the European and national investments and relies on the expertise of EGI.eu - a not-for-profit foundation that provides coordination to the EGI Community, including user groups, EGI.eu participants in the EGI Council, and the other collaborating partners.", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["EINFRA-1-2014 - Managing, preserving and computing with big research data"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Netherlands"], "Activity": ["Other", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Other", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Other", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-03-01"], "Project_ID": ["654142"], "Call_for_Proposal": ["H2020-EINFRA-2014-2"]}, -{"Partners": ["EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH", "WIRTSCHAFTSUNIVERSITAT WIEN", "FEI ELECTRON OPTICS BV", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN", "KARLSRUHER INSTITUT FUER TECHNOLOGIE", "UNIVERSITY OF GLASGOW", "UNIVERSITE DE GENEVE", "AMS AG", "CIS FORSCHUNGSINSTITUT FUR MIKROSENSORIK GMBH"], "EU_Contribution": ["EUR 3 872 524,56"], "Project_Title": ["Smart Sensor Technologies and Training for Radiation Enhanced Applications andMeasurements"], "Total_Cost": ["EUR 3 872 524,56"], "Country": ["Switzerland", "Austria", "Netherlands", "Germany", "France", "Germany", "Germany", "United Kingdom", "Switzerland", "Austria", "Germany"], "Project_ACR": ["STREAM"], "Technology_Description": "STREAM is a 4-year multi-site training network that aims at career development of Early Stage Researchers (ESRs) on", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Switzerland"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations"], "From": ["2016-01-01"], "Project_ID": ["675587"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V."], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["NANOSTRUCTURED LARGE AREA PLASMONIC SYSTEMSDEPOSITED BY GAS FLOW SPUTTERING AND PLASMA-ENHANCED CVD PROCESSES"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["NanoLAPS"], "Technology_Description": "Nanocomposites made of metallic nanoparticles (e.g. Au, Ag, Cu) embedded in a transparent matrix may display unique optical properties due to plasmonic effects resulting from the interaction of light with particles of nanometric size. This original behavior can be exploited in a wide range of applications including chemical and bio-sensors with extremely high sensitivity, spectroscopy, solar energy harvesting, and nanophotonics.", "To": ["2017-03-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations"], "From": ["2015-04-01"], "Project_ID": ["655628"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["FUNDACIO CENTRE DE REGULACIO GENOMICA"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Detection of Chromatin Bridges during Cytokinesis"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["NoCut"], "Technology_Description": "Duplication of the genome and its division into two daughter cells during mitosis is vital for survival of the organism. Cells have multiple mechanisms to ensure that this process is accomplished correctly thereby preserving the integrity of the genome. The final check before cell division is made by the NoCut abscission pathway. In yeast and animal cells, this mechanism monitors completion of chromosome separation, delaying abscission when chromosome bridges spanning the division site are detected. ", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2016-03-01"], "Project_ID": ["705602"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V."], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Development of a new immunoassay platform based on porous antibody microparticles"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["IMPAM"], "Technology_Description": "Rapid and sensitive analyte determination in small volumes is one of the main tasks in modern diagnostics for the development of miniaturized in vitro test systems. This is critically important for both health and environmental diagnostics. The traditional approach (ELISA) is a time-consuming multistep process with sensitivity limitations due to usually used planar supports for detection. In this project we intend to develop a new approach for biosensing based on porous antibody microparticles. For this purpose, the combination of a new technique to assemble porous particles at mild conditions (host know-how) and highly sensitive ELISA-based detection system (applicant know-how) will be used. The porous particles will work as a platform with two crucial features: i) specific immunochemical reactions are realized on highly developed particle surface, ii) separation and detection in small volumes (micrometer dimensions). We believe that the proposed approach may open new avenues in future for effective diagnostics.", "To": ["2017-09-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations"], "From": ["2015-10-01"], "Project_ID": ["657079"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["BILKENT UNIVERSITESI VAKIF"], "EU_Contribution": ["EUR 157 845,60"], "Project_Title": ["Quantifying and Protecting the Privacy of Genomic Data"], "Total_Cost": ["EUR 157 845,60"], "Country": ["Turkey"], "Project_ACR": ["GenoPri"], "Technology_Description": "Genomic data carries a lot of sensitive information about its owner such as his predispositions to sensitive diseases, ancestors, physical attributes, and genomic data of his relatives (leading to interdependent privacy risks). Individuals share vast amount of information on the Web, and some of this information can be used to infer their genomic data. Hence, there is a need to clearly understand the privacy risks on genomic data of individuals considering publicly available information on the Web. It is also crucial to protect genomic privacy of individuals without compromising the utilization of genomic data in research and healthcare.", "To": ["2018-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Turkey"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["707135"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V."], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["A mature Quokka for everyone \u2013 advancing the capabilities and accessibility of numerical solar cell simulations"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["Quokka Maturation"], "Technology_Description": "This project is placed in the field of photovoltaics (PV), which is on the eve of competing with conventional electricity generation on a purely economic basis, and is able to effectively tackle ecologic and socio-economic problems caused by the existing energy system based on fossil fuels.", "To": ["2018-01-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations"], "From": ["2016-02-01"], "Project_ID": ["655852"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "ECOLE FRANCAISE DE ROME"], "EU_Contribution": ["EUR 1 999 182,94"], "Project_Title": ["Promoting, Patronising and Practising the Arts in Roman Aristocratic Families (1644-1740). The Contribution of Roman Family Archives to the History of Performing Arts"], "Total_Cost": ["EUR 1 999 182,94"], "Country": ["France", "France", "Italy"], "Project_ACR": ["PERFORMART"], "Technology_Description": "Rome, centre of the Catholic Church and capital of the Papal States, strewn with churches and religious institutions, was also, in the 17th and 18th centuries, the scene of intense conflicts and rivalries between some twenty leading aristocratic families, highly adept at organising musical, theatrical and choreographic performances to display their political sympathies. The artistic life that animated the palaces and country villas of this elite has been far less studied than that of the papal court, the grand theatres or the principal churches of Rome. The PERFORMART project aims to enrich our understanding of the history of performing arts among the Roman nobility between 1644 and 1740 by exploiting the abundant documentation contained in the archives of eleven leading aristocratic families. The present proposal arises from the previous research of the principal investigator in the Orsini-Lante Archives. For the first time, PERFORMART will bring together specialised archivists and historians, all expert in different aspects of this micro-society, in a systematic collaboration between the history of the performing arts, choreographic studies, and art, music, social, and economic history. Via a relational database, this collaboration will bring to light original sources able to elucidate the social and artistic practices of Roman families, the motivations and conditions of patronage, the material framework of artistic productions, the status of the artist and his degree of dependence on his protectors, and, finally, the political, local and international impact of the involvement of these noble families on the artistic life of Rome.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations"], "From": ["2016-09-01"], "Project_ID": ["681415"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["UNIVERSITY OF STRATHCLYDE", "UNIVERSITY OF GLASGOW", "UNIVERSITE DE PAU ET DES PAYS DE L'ADOUR", "UNIVERSITA DEGLI STUDI DI CASSINO E DEL LAZIO MERIDIONALE", "UNIVERSITY OF DURHAM", "UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II.", "INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE", "TECHNISCHE UNIVERSITEIT DELFT", "CENTRE DE COOPERATION INTERNATIONALE EN RECHERCHE AGRONOMIQUE POUR LEDEVELOPPEMENT - C.I.R.A.D. EPIC", "CENTRE INTERNACIONAL DE METODES NUMERICS EN ENGINYERIA", "LIMITSTATE LIMITED", "NOBATEK", "KEMPFERT GEOTECHNIK GMBH", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE"], "EU_Contribution": ["EUR 3 954 945,78"], "Project_Title": ["Training Engineers and Researchers to Rethink geotechnical Engineering for a low carbon future"], "Total_Cost": ["EUR 3 954 945,78"], "Country": ["United Kingdom", "United Kingdom", "France", "Italy", "United Kingdom", "Italy", "France", "Netherlands", "France", "Spain", "United Kingdom", "France", "Germany", "Switzerland"], "Project_ACR": ["TERRE"], "Technology_Description": "TERRE aims to develop novel geo-technologies to address the competitiveness challenge of the European construction industry in a low carbon agenda. It will be delivered through an inter-sectoral and intra-European coordinated PhD programme focused on carbon-efficient design of geotechnical infrastructure. Industry and Research in the construction sector have been investing significantly in recent years to produce innovative low-carbon technologies. However, little innovation has been created in the geo-infrastructure industry, which is lagging behind other construction industry sectors. TERRE aims to close this gap through a network-wide training programme carried out by a close collaboration of eleven Universities and Research Centres and three SMEs. It is structured to provide a balanced combination of fundamental and applied research and will eventually develop operational tools such as software for low-carbon geotechnical design and a Decision Support System for infrastructure project appraisal. The research fellows will be involved in inter-sectoral and intra-European projects via enrolment in 8 \u2018Joint-Awards\u2019 and 7 \u2018Industrial\u2019 PhDs. The research fellows will be trained in low-carbon design by developing novel design concepts including eco-reinforced geomaterials, \u2018engineered\u2019 vegetation, engineered soil-atmosphere interfaces, biofilms, shallow geothermal energy and soil carbon sequestration. Distinctive features of TERRE are the supervision by an inter-sectoral team and the orientation of the research towards technological applications. Training at the Network level includes the development of entrepreneurial skills via a special programme on \u2018Pathways to Research Enterprise\u2019 to support the research fellows in establishing and leading spin-out companies after the end of the project.", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2015-11-01"], "Project_ID": ["675762"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V."], "EU_Contribution": ["EUR 1 907 325"], "Project_Title": ["Self-replicating Colloidal Assemblies"], "Total_Cost": ["EUR 1 907 325"], "Country": ["Germany", "Germany"], "Project_ACR": ["REPLICOLL"], "Technology_Description": "Self-replication is the preeminent property of living systems and natural materials. Nature builds and repairs by self-replication. Purely synthetic materials so far lack this important ability. An indispensable prerequisite is the multi-directional control of interactions between the building blocks of materials. In order to generate colloidal building blocks, which are able to self-replicate in a non-biological two-step process, i.e. without the use of DNA, we propose to create a new class of patchy colloidal particles bearing three patches of two different chemical functionalities. The new production process will yield precise control over the patch location and chemistry and thus also gives particles that go well beyond known ABA- or ABC-type Janus particles. ", "To": ["2020-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2015-07-01"], "Project_ID": ["648365"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "UNIVERSITAT LINZ", "RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN", "BUNDESANSTALT FUER MATERIALFORSCHUNG UND -PRUEFUNG", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.", "HIGH TECH COATINGS GMBH"], "EU_Contribution": ["EUR 3 024 827"], "Project_Title": ["Laser-induced Nanostructures as Biomimetic Model of Fluid Transport in the Integument of Animals"], "Total_Cost": ["EUR 3 024 827,50"], "Country": ["Greece", "Spain", "Austria", "Germany", "Germany", "Germany", "Austria"], "Project_ACR": ["LiNaBioFluid"], "Technology_Description": "The integument of an animal body has various functions, which are often achieved by specific micro- and/or nano- hierarchical structures. Examples are the very low water friction and air retention of water spiders or the swim fern of salvinia and the outstanding adhesion properties of geckos. In this project, we will employ advanced laser-processing strategies based on self-organization, to mimic the specific topography and the excellent wetting properties of the integument of bark bugs and moisture harvesting lizards resulting from adaptations to their environment. Flat bark bugs darken during rain fall due to a super-wettable body surface with capillaries out of which water spreads onto plain areas of the bug. For moisture harvesting in lizards wettability takes place in opposed direction, i.e. from plain areas into a capillary network on the skin. A fast and directional transport results from a special geometry of capillaries. Thus as general objective we want to test whether both effects, i.e. fast capillary transport (lizard) and liquid spreading onto plain areas (bark bugs), can be combined by optimized structures with hierarchical geometry. The outcome of this innovative biomimetic exploitation of wetting effects is expected to lead to a radically new technological approach of laser-generated surface textures on micro- and nanometer scale. Especially for control of friction and wear in liquids, leveraging new results can be expected, e.g. for developing slide bearings. The extension of surface structures over large areas is feasible. Thus, laser-fabrication of biomimetic surfaces with extreme wetting properties can be also anticipated in further applications, e.g. lubrication, water and oil separation, reduced drag in underwater applications, high power device cooling. All related to an innovative and sustainable reduction of CO2 emission.", "To": ["2018-06-30, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-1-2014 - FET-Open research projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Greece"], "Activity": ["Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-07-01"], "Project_ID": ["665337"], "Call_for_Proposal": ["H2020-FETOPEN-2014-2015-RIA"]}, -{"Partners": ["BSH ELECTRODOMESTICOS ESPANA SA", "AIRBUS DEFENCE AND SPACE GMBH", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.", "UNIVERSITEIT TWENTE", "UNIVERSIDAD POLITECNICA DE MADRID", "CENTRE TECHNOLOGIQUE ALPHANOV", "CONSIGLIO NAZIONALE DELLE RICERCHE", "THE UNIVERSITY OF BIRMINGHAM", "LEIBNIZ-INSTITUT FUR POLYMERFORSCHUNG DRESDEN EV", "ROBERT BOSCH GMBH"], "EU_Contribution": ["EUR 3 567 962,52"], "Project_Title": ["EUROPEAN ESRs NETWORK ON SHORT PULSED LASER MICRO/NANOSTRUCTURING OF SURFACES"], "Total_Cost": ["EUR 3 567 962,52"], "Country": ["Spain", "Germany", "Germany", "Netherlands", "Spain", "France", "Italy", "United Kingdom", "Germany", "Germany"], "Project_ACR": ["LASER4FUN"], "Technology_Description": "Today, industrial markets demand highly added value products offering new features at a low-cost. To this extent, technologies to modify surfaces instead of creating composites or applying coatings on surfaces can offer new industrial opportunities. Current state of the art identifies short pulsed(SP)/ultra-short pulsed(USP) laser-material processing as a promising technology for structuring surfaces and thus for embedding new functionalities for industrial applications. The LASER4FUN research programme pursues to go far beyond the current state through the development of new surface micro/nano-structuring/patterning methods by using emerging SP/USP laser technologies (LIPSS, DLIP, DLW & hybrid tech). The research will focus on the interaction of laser energy with several materials (metals, semiconductors, polymers, glasses & advanced materials) and on new surface functionalities like tribology, aesthetics and wettability.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Spain"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-09-01"], "Project_ID": ["675063"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "ARM LIMITED", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.", "SCAPOS AG", "THE UNIVERSITY OF MANCHESTER", "BULL SAS", "VIRTUAL OPEN SYSTEMS", "BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION", "FORSCHUNGSZENTRUM JULICH GMBH", "KALRAY SA", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 8 629 247,50"], "Project_Title": ["European Exascale Processor Memory Node Design"], "Total_Cost": ["EUR 8 629 247,50"], "Country": ["France", "United Kingdom", "Switzerland", "Greece", "Germany", "Germany", "United Kingdom", "France", "France", "Spain", "Germany", "France", "France"], "Project_ACR": ["ExaNoDe"], "Technology_Description": "ExaNoDe will investigate, develop integrate and validate the building blocks (technology readiness level 5) for a highly efficient, highly integrated, multi-way, high-performance, heterogeneous compute element aimed towards exascale computing. It will build on multiple European initiatives for scalable computing, utilizing low- power processors and advanced nanotechnologies. ExaNoDe will draw heavily on the Unimem memory and system design paradigm defined within the EUROSERVER FP7 project, providing low-latency, high-bandwidth and resilient memory access, scalable to Exabyte levels.", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["FETHPC-1-2014 - HPC Core Technologies, Programming Environments and Algorithms for Extreme Parallelism and Extreme Data Applications"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations"], "From": ["2015-10-01"], "Project_ID": ["671578"], "Call_for_Proposal": ["H2020-FETHPC-2014"]}, -{"Partners": ["FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS", "ICEOTOPE RESEARCH & DEVELOPMENT LTD", "ALLINEA SOFTWARE LIMITED", "ENGINSOFT SPA", "EXACT LAB SRL", "MONETDB SOLUTIONS B.V.", "VIRTUAL OPEN SYSTEMS", "ISTITUTO NAZIONALE DI ASTROFISICA", "ISTITUTO NAZIONALE DI FISICA NUCLEARE", "THE UNIVERSITY OF MANCHESTER", "UNIVERSITAT POLITECNICA DE VALENCIA", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V."], "EU_Contribution": ["EUR 8 442 547,50"], "Project_Title": ["European Exascale System Interconnect and Storage"], "Total_Cost": ["EUR 8 442 547,50"], "Country": ["Greece", "United Kingdom", "United Kingdom", "Italy", "Italy", "Netherlands", "France", "Italy", "Italy", "United Kingdom", "Spain", "Germany"], "Project_ACR": ["ExaNeSt"], "Technology_Description": "ExaNeSt will develop, evaluate, and prototype the physical platform and architectural solution for a unified Communication and Storage Interconnect and the physical rack and environmental structures required to deliver European Exascale Systems. The consortium brings technology, skills, and knowledge across the entire value chain from computing IP to packaging and system deployment; and from operating systems, storage, and communication to HPC with big data management, algorithms, applications, and frameworks. Building on a decade of advanced R&D, ExaNeSt will deliver the solution that can support exascale deployment in the follow-up industrial commercialization phases. Using direction from the ETP4HPC roadmap and soon-available high density and efficiency compute, we will model, simulate, and validate through prototype, a system with:", "To": ["2018-11-30, ongoing project"], "Meta": [""], "Topic_s": ["FETHPC-1-2014 - HPC Core Technologies, Programming Environments and Algorithms for Extreme Parallelism and Extreme Data Applications"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Greece"], "Activity": ["Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2015-12-01"], "Project_ID": ["671553"], "Call_for_Proposal": ["H2020-FETHPC-2014"]}, -{"Partners": ["BAYERISCHE JULIUS-MAXIMILIANS UNIVERSITAT WURZBURG", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "UPPSALA UNIVERSITET", "HELMHOLTZ-ZENTRUM BERLIN FUR MATERIALIEN UND ENERGIE GMBH", "IOLITEC IONIC LIQUIDS TECHNOLOGIES GMBH", "GABO:MI GESELLSCHAFT FUR ABLAUFORGANISATION:MILLIARIUM MBH & CO KG", "ARTTIC"], "EU_Contribution": ["EUR 3 872 980"], "Project_Title": ["Diamond materials for the photocatalytic conversion of CO2 to fine chemicals and fuels using visible light"], "Total_Cost": ["EUR 3 872 981,25"], "Country": ["Germany", "France", "Germany", "United Kingdom", "Sweden", "Germany", "Germany", "Germany", "France"], "Project_ACR": ["DIACAT"], "Technology_Description": "In DIACAT we propose the development of a completely new technology for the direct photocatalytic conversion of CO2 into fine chemicals and fuels using visible light. The approach utilises the unique property of man-made diamond, now widely available at low economic cost, to generate solvated electrons upon light irradiation in solutions (e.g. in water and ionic liquids). The project will achieve the following major objectives on the way to the efficient production of chemicals from CO2:", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-1-2014 - FET-Open research projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-07-01"], "Project_ID": ["665085"], "Call_for_Proposal": ["H2020-FETOPEN-2014-2015-RIA"]}, -{"Partners": ["THE UNIVERSITY OF EDINBURGH", "BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION", "KUNGLIGA TEKNISKA HOEGSKOLAN", "INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.", "DEUTSCHES ZENTRUM FUER LUFT - UND RAUMFAHRT EV", "T-SYSTEMS SOLUTIONS FOR RESEARCH GMBH", "UNIVERSITAT JAUME I DE CASTELLON", "THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 3 861 400,99"], "Project_Title": ["Programming Model INTERoperability ToWards Exascale (INTERTWinE)"], "Total_Cost": ["EUR 3 861 400,99"], "Country": ["United Kingdom", "Spain", "Sweden", "France", "Germany", "Germany", "Germany", "Spain", "United Kingdom"], "Project_ACR": ["INTERTWINE"], "Technology_Description": "This project addresses the problem of programming model design and implementation for the Exascale. The first Exascale computers will be very highly parallel systems, consisting of a hierarchy of architectural levels. To program such systems effectively and portably, programming APIs with efficient and robust implementations must be ready in the appropriate timescale. A single, \u201csilver bullet\u201d API which addresses all the architectural levels does not exist and seems very unlikely to emerge soon enough. We must therefore expect that using combinations of different APIs at different system levels will be the only practical solution in the short to medium term. Although there remains room for improvement in individual programming models and their implementations, the main challenges lie in interoperability between APIs. It is this interoperability, both at the specification level and at the implementation level, which this project seeks to address and to further the state of the art. INTERTWinE brings together the principal European organisations driving the evolution of programming models and their implementations. The project will focus on seven key programming APIs: MPI, GASPI, OpenMP, OmpSs, StarPU, QUARK and PaRSEC, each of which has a project partner with extensive experience in API design and implementation. Interoperability requirements, and evaluation of implementations will be driven by a set of kernels and applications, each of which has a project partner with a major role in their development. The project will implement a co- design cycle, by feeding back advances in API design and implementation into the applications and kernels, thereby driving new requirements and hence further advances.", "To": ["2018-09-30, ongoing project |"], "Meta": [""], "Topic_s": ["FETHPC-1-2014 - HPC Core Technologies, Programming Environments and Algorithms for Extreme Parallelism and Extreme Data Applications"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["671602"], "Call_for_Proposal": ["H2020-FETHPC-2014"]}, -{"Partners": ["FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V."], "EU_Contribution": ["EUR 410 093,75"], "Project_Title": ["Observing Emergence"], "Total_Cost": ["EUR 410 093,75"], "Country": ["Germany"], "Project_ACR": ["OBSERVE"], "Technology_Description": "In line with the mission of the FET programme the overarching aim of OBSERVE is to support Europe to grasp leadership early on in new and emerging technology areas that promise to renew the basis for European competitiveness and growth and that will make a difference for society in the decades to come. For this purpose OBSERVE addresses the concrete objective of identifying new opportunities and directions for interdisciplinary research towards new and visionary technology of any kind. More specifically OBSERVE will:", "To": ["2017-05-31, closed project"], "Meta": [""], "Topic_s": ["FETOPEN-2-2014 - Coordination and Support Activities"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations"], "From": ["2015-06-01"], "Project_ID": ["665136"], "Call_for_Proposal": ["H2020-FETOPEN-2014-CSA"]}, -{"Partners": ["FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.", "AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH"], "EU_Contribution": ["EUR 383 593,50"], "Project_Title": ["Tracing impacts of the FET programme"], "Total_Cost": ["EUR 383 593,75"], "Country": ["Germany", "Austria"], "Project_ACR": ["FET_TRACES"], "Technology_Description": "The FET_Traces project will measure and assess the direct and indirect impacts of the FET programme on the science and technology landscape and its perception by individual researchers who are potential proposers for FET Open and FET Proactive projects. The impact assessment will be based on a comprehensive theoretic foundation, it will develop a targeted indicator set covering central aspects of the FET mission like novelty, multi-disciplinarity, innovation eco-systems, and becoming a relevant player in the European funding landscape. ", "To": ["2017-11-14, closed project"], "Meta": [""], "Topic_s": ["FETOPEN-2-2014 - Coordination and Support Activities"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2015-07-15"], "Project_ID": ["665083"], "Call_for_Proposal": ["H2020-FETOPEN-2014-CSA"]}, -{"Partners": ["UNIVERSITAT POLITECNICA DE CATALUNYA", "STICHTING DELTARES", "CHALMERS TEKNISKA HOEGSKOLA AB", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.", "ASSOCIATION POUR LA RECHERCHE ET LE DEVELOPPEMENT DES METHODES ET PROCESSUS INDUSTRIELS", "KATHOLIEKE UNIVERSITEIT LEUVEN", "STICHTING KATHOLIEKE UNIVERSITEIT"], "EU_Contribution": ["EUR 2 404 943"], "Project_Title": ["Global systems Rapid Assessment tools through Constraint FUnctional Languages"], "Total_Cost": ["EUR 2 404 943,75"], "Country": ["Spain", "Netherlands", "Sweden", "Germany", "France", "Belgium", "Netherlands"], "Project_ACR": ["GRACeFUL"], "Technology_Description": "The making of policies coping with Global Systems is a process that necessarily involves stakeholders from diverse disciplines, each with their own interests, constraints and objectives. People play a central role in such collective decision making and the quest for solutions to a problem generally intertwines its very specification. ", "To": ["2018-01-31, closed project"], "Meta": [""], "Topic_s": ["FETPROACT-1-2014 - Global Systems Science (GSS)"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-02-01"], "Project_ID": ["640954"], "Call_for_Proposal": ["H2020-FETPROACT-2014"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI PARMA", "HELSINGIN YLIOPISTO", "ITA-SUOMEN YLIOPISTO", "LATVIJAS ORGANISKAS SINTEZES INSTITUTS", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "UNIVERZA V LJUBLJANI", "TAROS CHEMICALS GMBH & CO KG", "UNIVERSITEIT ANTWERPEN", "APTUIT (VERONA) SRL", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V."], "EU_Contribution": ["EUR 2 793 330,72"], "Project_Title": ["Interdisciplinary Training Network for Validation of Gram-Negative Antibacterial Targets"], "Total_Cost": ["EUR 2 793 330,72"], "Country": ["Italy", "Finland", "Finland", "Latvia", "United Kingdom", "Slovenia", "Germany", "Belgium", "Italy", "Germany"], "Project_ACR": ["INTEGRATE"], "Technology_Description": "Antimicrobial resistance is posing a continuously-rising threat to global health. Indeed, one key recommendation from the recent \u201cAction plan against the rising threats from Antimicrobial Resistance\u201d report (submitted by the Commission to the European Parliament and Council (15.11.2011)) is the development of effective antimicrobials or alternatives for treatment of human and animal infections. The INTEGRATE project is a direct response to this. We have assembled a team of 10 beneficiaries from eight EU member states, encompassing both academic and non-academic sectors and different disciplines, to form a consortium committed to training Early Stage Researchers (ESRs) in the discovery and preclinical validation of novel Gram-negative antibacterial agents and antibacterial targets. The principle aim of the consortium is to provide a training platform where students are exposed to every aspect of the antimicrobial discovery process, ranging from target identification and validation, through organic synthesis, in silico design and compound screening, to mode-of-action and possible resistance mechanisms. This exposure will be accomplished through a concrete secondment plan, coupled with a series of high-level consortium-wide training events and networking programmes. Our intention is to reverse the current fragmentation of approaches towards antibacterial discovery through mutual cooperation. The INTEGRATE training framework is built on an innovative research project aimed at targeting important but non-essential gene products as an effective means of reducing bacterial fitness, thereby facilitating clearance of the pathogen by the host immune system. To achieve this, the individual work programmes have been designed to seamlessly inter-mesh contributions from the fields of in silico design, organic synthesis, molecular biology and biochemistry, and the very latest in vitro and in vivo screening technologies.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations"], "From": ["2015-01-01"], "Project_ID": ["642620"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["UNIVERSITAT POLITECNICA DE VALENCIA"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["ZEolitic reactor hosting Subphthalocyanines and Metal Oxides as photocatalytic system for opto-electronic applications"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["ZESMO"], "Technology_Description": "Solar light promoted CO2 reduction could be the \u201cgreenest\u201d alternative to fossil fuels as it would also decrease the atmospheric CO2 emissions. ZESMO comes from the idea of developing an efficient, robust and low-cost photocatalytic system to improve reported conversion rates for CO2 reduction by H2O. Some of the problems to overcome are the limited wavelength response (frequently limited to only 4% of the total solar light energy), photo-corrosion and low quantum efficiencies. The photocatalyst presented in this proposal is designed to tackle these issues and achieve a better performance by incorporating Suphthalocyanine (SubPc) (light harvester) and metal clusters (semiconductor) into zeolites. Zeolite\u2019s pores act as \u201cnano-reactors\u201d entrapping both species and enhancing chemical stability and catalytic activity. The second part of the project deals with the evaluation of the photocatalytic activity of a series of synthesised hybrids. The system will be subjected to operation lifetime studies for its possible future commercialisation. ", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["709023"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V."], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["High efficiency GaInP/GaAs Tandem wafer bonded solar cell on silicon"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["HISTORIC"], "Technology_Description": "Direct conversion of photons into electricity is a promising clean energy solution to answer the challenge of energy supply security, competitiveness of the EU industry, electricity prices and climate change. Monocrystalline silicon (c-Si), the dominant technology on the photovoltaic (PV) market, benefits from a strong industry and record power conversion efficiency of 25%, with a cost decreasing every year. However, c-Si technology, mainly limited by material properties, has very little room for efficiency improvement. Much higher efficiencies has been achieved by stacking diodes made of III-V semiconductors; but for cost and availability reasons, the III-V solar cells are restricted to specific markets (space & terrestrial concentration). A hybrid solution combining the advantages III-V multi-junction cells with the benefits of Si, the most wide-spread PV material, offers great opportunities. Indeed, efficiencies up to 35% under 1-sun AM1.5G conditions is expected for a triple junction device based on conventional c-Si cells combined with additional (Al)GaAs and GaInP pn-junctions (4 \u00b5m of III-V material on top of a c-Si wafer). However the direct epitaxial growth of (Al)GaAs & GaInP on Si is highly mismatched and sufficient material quality has not been achieved so far. The innovative approach proposed in this project bypass the mismatch and enables to combine high crystal quality III-V compounds with Si through wafer bonding: III-V layers are grown lattice matched on GaAs or Ge and then bonded to Si, followed by substrate lift-off & re-use. The validity of the approach has been proven at Fraunhofer ISE with un-optimized GaInP/GaAs//Si triple-junction solar cells with >25% efficiency. This research project, relying on modeling and experimental work to optimize the cell structure (light trapping, bond interface quality, current matching, etc.), targets the significant breakthrough of a GaInP/GaAs//Si triple junction reaching >30% efficiency on large areas (>4cm2).", "To": ["2017-05-31, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations"], "From": ["2015-06-01"], "Project_ID": ["655272"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSIDADE DE AVEIRO", "HELMHOLTZ-ZENTRUM GEESTHACHT ZENTRUM FUR MATERIAL- UND KUSTENFORSCHUNG GMBH", "LATVIJAS UNIVERSITATES POLIMERU MEHANIKAS INSTITUTS", "SMALLMATEK - SMALL MATERIALS AND TECHNOLOGIES LDA", "SYNPO AKCIOVA SPOLECNOST"], "EU_Contribution": ["EUR 900 000"], "Project_Title": ["Development of Smart Nano and Microcapsulated Sensing Coatings for improving of Material Durability/Performance"], "Total_Cost": ["EUR 900 000"], "Country": ["Portugal", "Germany", "Latvia", "Portugal", "Czech Republic"], "Project_ACR": ["SMARCOAT"], "Technology_Description": "The proposal aims to develop an innovative approach to impart sensing functionality and detect substrate degradation. The degradation processes targeted will be corrosion of metallic substrates and mechanical damage by impact on fibre reinforced plastics and composites (FRP), used as structural components in the vehicle industry worldwide.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Portugal"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["645662"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "CENTRE FOR RENEWABLE ENERGY SOURCES AND SAVING FONDATION", "European Distributed Energy Resources Laboratories e.V.", "DNV GL NETHERLANDS B.V.", "KEMA NEDERLAND BV", "DANMARKS TEKNISKE UNIVERSITET", "ENEL INGEGNERIA E RICERCA SPA", "ENEL PRODUZIONE SPA", "INSTITUT POLYTECHNIQUE DE GRENOBLE", "INSTITUTE OF COMMUNICATION AND COMPUTER SYSTEMS", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.", "ORMAZABAL CORPORATE TECHNOLOGY, A.I.E.", "OFFIS EV", "RICERCA SUL SISTEMA ENERGETICO - RSE SPA", "SINTEF ENERGI AS", "FUNDACION TECNALIA RESEARCH & INNOVATION", "TECHNISCHE UNIVERSITEIT DELFT", "UNIVERSITY OF STRATHCLYDE", "Teknologian tutkimuskeskus VTT Oy"], "EU_Contribution": ["EUR 9 999 987"], "Project_Title": ["European Research Infrastructure supporting Smart Grid Systems Technology Development, Validation and Roll Out"], "Total_Cost": ["EUR 9 999 987"], "Country": ["Austria", "France", "Greece", "Germany", "Netherlands", "Netherlands", "Denmark", "Italy", "Italy", "France", "Greece", "Germany", "Spain", "Germany", "Italy", "Norway", "Spain", "Netherlands", "United Kingdom", "Finland"], "Project_ACR": ["ERIGrid"], "Technology_Description": "Renewable energy sources are key enablers to decrease greenhouse gas emissions and to cope with the anthropogenic global warming. The intermittent behaviour of them and their limited storage capabilities present new challenges to power system operators in maintaining power quality and reliability. However, the increased availability of advanced automation and communication technologies has also provided new intelligent solutions to these challenges. Previous work has presented various new methods to operate highly interconnected power grids with corresponding components in a more effective way. As a consequence of these developments the traditional power system is transformed into a cyber-physical system, a Smart Grid. Previous and ongoing research activities have mainly focused on validating certain aspects of Smart Grids, but until now no integrated approach for analysing and evaluating complex configurations in a cyber-physical systems manner is available. ", "To": ["2020-04-30, ongoing project |"], "Meta": [""], "Topic_s": ["INFRAIA-1-2014-2015 - Integrating and opening existing national and regional research infrastructures of European interest"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Austria"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2015-11-01"], "Project_ID": ["654113"], "Call_for_Proposal": ["H2020-INFRAIA-2014-2015"]}, -{"Partners": ["UNIVERSITY OF SURREY", "INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE", "THE UNIVERSITY OF EDINBURGH", "TECHNISCHE UNIVERSITAET MUENCHEN", "INSTITOUTO TECHNOLOGIAS YPOLOGISTONKAI EKDOSEON DIOFANTOS", "INSTITUTO DE TELECOMUNICACOES", "TTY-SAATIO", "NOISELESS IMAGING OY", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V."], "EU_Contribution": ["EUR 3 866 329,44"], "Project_Title": ["Machine Sensing Training Network"], "Total_Cost": ["EUR 3 866 329,44"], "Country": ["United Kingdom", "France", "United Kingdom", "Germany", "Greece", "Portugal", "Finland", "Finland", "Germany"], "Project_ACR": ["MacSeNet"], "Technology_Description": "The aim of this Innovative Training Network is to train a new generation of creative, entrepreneurial and innovative early-stage researchers (ESRs) in the research area of measurement and estimation of signals using knowledge or data about the underlying structure. With its combination of ideas from machine learning and sensing, we refer to this research topic as \u201cMachine Sensing\u201d. We will train all ESRs in research skills needed to obtain an internationally-recognized PhD; to experience applying their research a non-Academic sector; and to gain transferrable skills such as entrepreneurship and communication skills. We will further encourage an open \u201creproducible research\u201d approach to research, through open publication of research papers, data and software, and foster an entrepreneurial and innovation-oriented attitude through exposure to SME and spin-out Partners in the network. In the research we undertake, we will go beyond the current, and hugely popular, sparse representation and compressed sensing approaches, to develop new signal models and sensing paradigms. These will include those based on new structures, nonlinear models, and physical models, while at the same time finding computationally efficient methods to perform this processing. We will develop new robust and efficient Machine Sensing theory and algorithms, together methods for a wide range of signals, including: advanced brain imaging; inverse imaging problems; audio and music signals; and non-traditional signals such as signals on graphs. We will apply these methods to real-world problems, through work with non-Academic partners, and disseminate the results of this research to a wide range of academic and non-academic audiences, including through publications, data, software and public engagement events.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations"], "From": ["2015-01-01"], "Project_ID": ["642685"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["UNIVERSITAT DE GIRONA", "EASY INNOVA S.L.", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.", "ADMIN LEUVEN bvba"], "EU_Contribution": ["EUR 378 000"], "Project_Title": ["Social, complementary or community virtual currencies transfer of knowledge to SME: a new era for competitiveness and entrepreneurship"], "Total_Cost": ["EUR 378 000"], "Country": ["Spain", "Spain", "Germany", "Belgium"], "Project_ACR": ["VirCoin2SME"], "Technology_Description": "With the advent of social networks and Mobile networks, new online communities are being created around sustainable topics (environmental, social, community development). The phenomena, known as digital social innovation, generates a positive ecosystem where business and social development enabled with new behaviours boosted by social, complementary or community currencies deployed as virtual currencies have a great potential for competitiveness, and entrepreneurship, but also for fostering social responsibility in Europe. ", "To": ["2016-11-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2014-12-01"], "Project_ID": ["645767"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["KURATORIUM FUER VERKEHRSSICHERHEIT", "\"HELLENIC RESEARCH AND EDUCATIONAL INSTITUTE \"\"PANOS MYLONAS\"\" FOR THE ROAD SAFETY AND THE PREVENTION/REDUCTION OF TRAFFIC ACCIDENTS\"", "TALLINNA TEHNIKAULIKOOL", "CO-PLAN INSTITUTI PER ZHVILLIMIN EHABIITATIT", "MIDDLE EAST TECHNICAL UNIVERSITY", "SUOMALAINEN LIIKENNETUTKIMUSKESKUS OY", "UNIVERSITETI POLIS SHPK", "STICHTING WETENSCHAPPELIJK ONDERZOEK VERKEERSVEILIGHEID", "TELECOMMUNICATION AND COMPUTER NETWORKING TNC SHPK", "TECHNISCHE UNIVERSITAET WIEN"], "EU_Contribution": ["EUR 499 500"], "Project_Title": ["Traffic Safety Cultures and the Safe Systems Approach \u2013 Towards a Cultural Change Research and Innovation Agenda for Road Safety"], "Total_Cost": ["EUR 499 500"], "Country": ["Austria", "Greece", "Estonia", "Albania", "Turkey", "Finland", "Albania", "Netherlands", "Albania", "Austria"], "Project_ACR": ["TraSaCu"], "Technology_Description": "Traffic Safety Culture (TraSaCu) aims at developing a cultural approach in road traffic safety research and accident prevention. Traditional approaches to traffic safety shall be complemented by a cultural perspective which has emerged recently in safety research and prevention. Safety culture has been identified as an important factor of road safety as it helps understanding and explaining the typical patterns of risk perception and risk taking that prevail in different national, regional or local traffic systems as well as their relationships with numbers and forms of accidents. A weak safety culture produce higher numbers of accidents which are more severe. A strong safety culture helps reducing the number of accidents as well as mitigating their severity. It strengthens safety relevant attitudes and behaviour and it is also a condition for making road safety measures more effective.", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Austria"], "Activity": ["Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Other", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2015-03-01"], "Project_ID": ["645690"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF EV", "CHALMERS TEKNISKA HOEGSKOLA AB", "TECHNISCHE UNIVERSITEIT DELFT", "INSTITUT NATIONAL POLYTECHNIQUE DE TOULOUSE", "KARLSRUHER INSTITUT FUER TECHNOLOGIE", "LAPPEENRANNAN TEKNILLINEN YLIOPISTO", "TECHNICKA UNIVERZITA V LIBERCI", "POLITECHNIKA LODZKA", "UNIVERSITY OF BATH", "ITA-SUOMEN YLIOPISTO"], "EU_Contribution": ["EUR 3 819 642,12"], "Project_Title": ["Smart tomographic sensors for advanced industrial process control"], "Total_Cost": ["EUR 3 819 642,12"], "Country": ["Germany", "Sweden", "Netherlands", "France", "Germany", "Finland", "Czech Republic", "Poland", "United Kingdom", "Finland"], "Project_ACR": ["TOMOCON"], "Technology_Description": "A decisive gap in the process industry is the lack of qualified distributed process parameter measurements for optimal control. Process tomography is a ground-breaking technology to bridge this gap. Just with the recent development in high-power massive parallel computing this technology has gained the required real-time capability. TOMOCON as a European network of leading academic and industrial partners from different sectors dedicates its efforts in research and training towards development of tomography-based industrial process control. With that it shall generate new scientific and technical knowledge in this emerging field; develop and demonstrate new technological solutions of advanced industrial control by tomographic sensors; align tomography-based process control with concepts of knowledge-based control, big data analysis and advanced human-machine interfaces; and enhance the scientific and transferable skills of early stage researchers to meet future needs of the industry. Together with world-leading industrial sensor and control solution providers, process engineering and production companies TOMOCON shall demonstrate the functionality of tomography-assisted process control in four industry-relevant demonstration cases, which serve as benchmarks to demonstrate improvements in energy and resource efficiency as well as product quality. That is: control of inline fluid separation, control of microwave drying processes, control of continuous metal casting, and control of batch crystallization processes.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["764902"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["Fundacion IMDEA Energia", "NORTHWESTERN UNIVERSITY"], "EU_Contribution": ["EUR 239 191,20"], "Project_Title": ["Solar Energy Storage PERovskites"], "Total_Cost": ["EUR 239 191,20"], "Country": ["Spain", "United States"], "Project_ACR": ["SESPer"], "Technology_Description": "Solar energy, attractive source of energy being it free and endless, can be converted into electricity by means of a Concentrating Solar Power (CSP) plant. However, the biggest limit of such technology is the intermittency and the diurnal nature of the solar light. For their future development, CSP plants need to be coupled with storage system. Among the existing thermal storage systems, the ThermoChemical Storage (TCS) is one of the most promising technology and it is based on the exploitation of the reaction heat of a reversible chemical reaction. Just recently, perovskite systems have drawn increasing interest as promising candidates for TCS systems. Perovskites are generally indicated as ABO3, with A and B the two cations of the structure and with O the oxygen. They exhibit a continuous, quasi-linear oxygen release/uptake within a very wide temperature range. Their reduction being endothermic consists in the heat storage step, while the exothermic oxidation releases heat when it is required. The overall objective of the proposal is to study more earth abundant compositions (Ca-, Fe-, Mn- or Co-based) of perovskites for identifying one or more promising candidate storage medium for the design and the realization of a prototype of a multilevel-cascaded TCS system. It aims at solving the no-easy solution problem of the wide temperature range to be covered by a TCS system for CSP plant by using perovskites with different operating temperatures cascaded from the lowest operating temperature to the maximum one. As main result it could bring the TCS systems to a level closer to the market scale. The research project will be developed in collaboration with the IMDEA Energy Institute and the Materials Science and Engineering Department of Northwestern University. This project idea is totally in line with the current strict global energy and environmental politics and also with the Horizon 2020 objectives.", "To": ["2020-11-12, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2017-11-13"], "Project_ID": ["746167"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSIDAD DE NAVARRA", "THE UNIVERSITY OF EDINBURGH", "ADURO BIOTECH EUROPE BV", "FUNDACION PARA LA INVESTIGACION MEDICA APLICADA FIMA"], "EU_Contribution": ["EUR 1 279 782,36"], "Project_Title": ["Training Network for the education of the next generation scientist in targeting the supressive capacity of regulatory T-cells specifically within tumours"], "Total_Cost": ["EUR 1 279 782,36"], "Country": ["Spain", "United Kingdom", "Netherlands", "Spain"], "Project_ACR": ["Tumor-Treg-Targeting"], "Technology_Description": "Tumour immune-therapy has made dramatic improvements in recent years, saving the lives of cancer patients who just a few years ago would have been considered untreatable. It thereby became apparent that one specific type of immune cell, so called regulatory T-cells, critically hampers the efficacy of tumour immune-therapy. Tumours, however, attract and exploit the immune-regulatory function of Tregs to dampen local immune responses and to induce local tolerance.", "To": ["2022-05-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations"], "From": ["2018-06-01"], "Project_ID": ["765394"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["TECHNISCHE UNIVERSITAET WIEN"], "EU_Contribution": ["EUR 166 156,80"], "Project_Title": ["BioNetIllustration: User centric illustrations of biological networks"], "Total_Cost": ["EUR 166 156,80"], "Country": ["Austria"], "Project_ACR": ["BioNetIllustration"], "Technology_Description": "In living systems, one molecule is commonly involved in several distinct physiological functions. The roles of molecules are commonly summarized in pathway diagrams, which, however, are abstract, hierarchically nested and thus is difficult to comprehend especially by non-expert audience. The primary goal of this research in visualization is to intuitively support the comprehensive understanding of relationships among biological networks using interactively computed illustrations. Illustrations, especially in textbooks of biology are carefully designed to clearly present reactions between organs as well as interactions within cells. Automatic generation of illustrative visualizations of biological networks is thus the technical content of this proposal. Automatic generation of hand-drawn illustrations has been a challenging task due to the difficulty of algorithmically describing a human creative process such as evaluating and selecting significant information and composing meaningful explanations in a visually plausible manner. Our high-level idea in BioNetIllustration is to simulate this process by decomposing the entire problem into multiple steps including content-driven layout and illustration design as well as spatio-temporal event transitions across multiple representations. As a pioneer study on illustrations, a new visualization framework for these network illustrations will be developed. This study can be achieved by matching the unique competences of the researcher and the host research group and allows an innovative synthesis to produce hand-drawn like illustrations of biological networks. The project also involves experts from several disciplines including network and medical visualization, data mining, systems biology as well as perceptual psychology. The result will provide a new direction for physiological process analysis and accelerate the knowledge transfer not only within experts but also to the public.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["747985"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["DANMARKS TEKNISKE UNIVERSITET", "TECHNISCHE UNIVERSITAET WIEN", "MAELARDALENS HOEGSKOLA", "TECHNISCHE UNIVERSITAET KAISERSLAUTERN", "TTTECH COMPUTERTECHNIK AG", "SYSGO AG", "ABB AB"], "EU_Contribution": ["EUR 4 000 793,40"], "Project_Title": ["Fog Computing for Robotics and Industrial Automation"], "Total_Cost": ["EUR 4 000 793,40"], "Country": ["Denmark", "Austria", "Sweden", "Germany", "Austria", "Germany", "Sweden"], "Project_ACR": ["FORA"], "Technology_Description": "We are at the beginning of a new industrial revolution (Industry 4.0): disruptive technologies such as cyber-physical systems, machine-to-machine communication, Big Data and machine learning, and human-robot collaboration will transform the manufacturing and industrial automation sectors. However, Industry 4.0 will only become a reality through the convergence of Operational and Information Technologies (OT & IT). The European Parliament, says that \u201ca very wide range of skills is required for [Industry 4.0] implementation. [\u2026] the convergence of IT, manufacturing, automation technology and software requires the development of a fundamentally new approach to training IT experts.\u201d The FORA interdisciplinary, international, intersectoral network will train the next generation of researchers to lead this convergence and cross the IT-OT gap. The convergence will be achieved through the new concept of Fog Computing, which is a logical extension from Cloud Computing towards the edge of the network (where machines are located), enabling applications that demand guarantees in safety, security, and real-time behavior. Research objectives focus on: a reference system architecture for Fog Computing; resource management mechanisms and middleware for deploying mixed-criticality applications in the Fog; safety and security assurance; service-oriented application modeling and real-time machine learning. Our ambitious objectives require individuals with a unique combination of interdisciplinary and intersectoral skills. Thus, FORA\u2019s 15 ESRs will receive integrated training across key areas (computer science, electrical engineering, control engineering, industrial automation, applied mathematics and data science) necessary to fully realize the potential of Fog Computing for Industry 4.0 and will move between academic and industrial environments to promote interdisciplinary and intersectoral learning.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-10-01"], "Project_ID": ["764785"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["CENTRE INTERNACIONAL DE METODES NUMERICS EN ENGINYERIA", "UNIVERSITA DEGLI STUDI DI PAVIA", "SWANSEA UNIVERSITY", "TECHNISCHE UNIVERSITAET MUENCHEN", "ECOLE CENTRALE DE NANTES", "INSTITUTO SUPERIOR TECNICO", "UNIVERSITE LIBRE DE BRUXELLES", "TECHNISCHE UNIVERSITEIT EINDHOVEN"], "EU_Contribution": ["EUR 3 831 509,88"], "Project_Title": ["Industrial decision-making on complex production technologies supported by simulation-based engineering"], "Total_Cost": ["EUR 3 831 509,88"], "Country": ["Spain", "Italy", "United Kingdom", "Germany", "France", "Portugal", "Belgium", "Netherlands"], "Project_ACR": ["ProTechTion"], "Technology_Description": "Simulation-based engineering (SBE), in which traditional R&D, design and production technologies are complemented with computer simulations, has revolutionized the industrial sector. Computer simulations are critical for control of manufacturing processes, non-destructive-testing and decision-making at production phases, and shorten the lead-time of design and development processes, thus reducing both costs and time-to-market. ", "To": ["2022-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EJD - European Joint Doctorates"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["764636"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["TTY-SAATIO", "SVEUCILISTE U ZAGREBU FAKULTET ELEKTROTEHNIKE I RACUNARSTVA", "UNIVERSITA DEGLI STUDI ROMA TRE", "NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU", "MAELARDALENS HOEGSKOLA", "LEONARDO - SOCIETA PER AZIONI", "CROSSCONTROL AB", "XYLON DOO", "BENEQ OY"], "EU_Contribution": ["EUR 3 957 576,84"], "Project_Title": ["Immersive Visual Technologies for Safety-critical Applications"], "Total_Cost": ["EUR 3 957 576,84"], "Country": ["Finland", "Croatia", "Italy", "Norway", "Sweden", "Italy", "Sweden", "Croatia", "Finland"], "Project_ACR": ["ImmerSAFE"], "Technology_Description": "In many contexts \u2013 heavy work machines, emergency response, control centres \u2013 human operators face complex and demanding situations where their decisions can have far-reaching consequences on productivity, environment, and even human lives. In order to deal with such challenges, the operator needs full situational awareness, which can be achieved by sensing relevant visual data about the operating environment, refining it into mission-critical information, and presenting it in an immersive, intuitively comprehensible manner. This can be achieved by Immersive Visual Technologies (IVT) delivering ultra-realistic and interactive visual experience. ", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-01-01"], "Project_ID": ["764951"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["TTY-SAATIO", "UNIVERSITEIT MAASTRICHT", "KEMIRA OYJ", "KUNGLIGA TEKNISKA HOEGSKOLAN", "KATHOLIEKE UNIVERSITEIT LEUVEN", "PREDILNICA LITIJA DOO", "TECHNISCHE UNIVERSITAET GRAZ", "UNIVERZA V MARIBORU"], "EU_Contribution": ["EUR 3 832 629,48"], "Project_Title": ["A Training Network on Designing Novel Bio-based Fibre Products for Targeted Advanced Properties and New Applications"], "Total_Cost": ["EUR 3 832 629,48"], "Country": ["Finland", "Netherlands", "Finland", "Sweden", "Belgium", "Slovenia", "Austria", "Slovenia"], "Project_ACR": ["FibreNet"], "Technology_Description": "FibreNet will train young fibre-professionals having multidisciplinary view to develop sustainable bio-based fibre products with tailored properties for different application fields in both academic and non-academic sectors. Bio-based fibre products are one of the corner-stones in the European bio-based industry corresponding to 12% of the employment in manufacturing. The industry, including such sectors as packaging, paper, biocomposites and biomedical and hygienic textiles, is currently undergoing a fundamental transformation in order to respond to the competition raised i) by low-wage countries and ii) by fossil-based materials. A common consensus in Europe is that to remain competitive and sustain the bio-based fibre industries in Europe, we should focus on developing new high added value products that have specific functionalities but reduced environmental impacts.", "To": ["2021-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["764713"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA", "TOYOTA MOTOR EUROPE"], "EU_Contribution": ["EUR 743 618,88"], "Project_Title": ["European Industrial Doctorate in Innovative POLYmers for Lithium Battery TEchnologies"], "Total_Cost": ["EUR 743 618,88"], "Country": ["Spain", "Belgium"], "Project_ACR": ["POLYTE"], "Technology_Description": "POLYTE-EID European Industrial Doctorate will offer excellent training opportunities to 3 Early Stage Researchers in the area of Polymers for Electrochemical Energy Storage. POLYTE-EID puts together the expertise in batteries for automotive of Toyota Motor Europe (TME) with the academic excellence in polymers of the University of the Basque Country (POLYMAT). The final objective is to train scientists who may face some of the upcoming European energy and transportation challenges. The project proposal is a well-balanced combination of fundamental material&polymer science with applied research in electrochemical energy storage technologies. The project will search the development of new polymeric materials to increase the performance and security of actual and future batteries.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-01-01"], "Project_ID": ["765828"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI PERUGIA", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.", "KAUNO TECHNOLOGIJOS UNIVERSITETAS", "KATHOLIEKE UNIVERSITEIT LEUVEN", "UNIVERSITE DE NANTES", "UNIVERSITY OF NEWCASTLE UPON TYNE", "Research Center for Non Destructive Testing GmbH", "TWI LIMITED", "THE UNIVERSITY OF WARWICK", "BRUSSELS AIRLINES"], "EU_Contribution": ["EUR 3 808 670,04"], "Project_Title": ["NDTonAIR: Training Network in Non-Destructive Testing and Structural Health Monitoring ofAircraft structures"], "Total_Cost": ["EUR 3 808 670,04"], "Country": ["Italy", "France", "Germany", "Lithuania", "Belgium", "France", "United Kingdom", "Austria", "United Kingdom", "United Kingdom", "Belgium"], "Project_ACR": ["NDTonAIR"], "Technology_Description": "The \u201cNDTonAIR\u201d consortium involves Universities, Research Organisations and major European companies working on new Non-Destructive Testing (NDT) and Structural Health Monitoring (SHM) techniques for aerospace, of which both are key technologies. The goal is to train a new generation of scientists and engineers with a wide background of theoretical and experimental skills, capable of developing their research and entrepreneurial activities both in academy and industry and playing an active role in promoting the importance of quality inspection and structural monitoring in aerospace components. ", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-10-01"], "Project_ID": ["722134"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Simple fusion systems and linking systems"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["FusionSystems"], "Technology_Description": "The classification of finite simple groups is often regarded as one of the major mathematical achievements of the 20th century. Its importance lies not only in the fundamental result, but also in the methodology and conceptual framework developed for its proof. Most intriguingly, it turned out that the structure of a finite group is closely connected to the structure of the p-local subgroups, i.e. the normalizers of non-trivial p-subgroups, for a suitably chosen prime p. Of particular importance is the prime 2. Even though the proof of the classification of finite simple groups is insightful in its major conceptual approach, it is extremely long and difficult in its details. Thus, it would be of great interest to obtain a simplified proof. Moreover, to gain the maximum benefit from the methods of the proof of the classification, it is highly desirable to work in a more general context which in particular allows also for applications in the modular representation theory of finite groups. Saturated fusion systems provide a conceptual framework for this and connect to important questions in homotopy theory. A program to find a new and better proof of the classification of finite simple groups through a classification of simple fusion systems at the prime 2 has been recently outlined by Aschbacher. Two parts of our proposal concern classification problems for fusion systems. Their significance lies not only in completing important cases in Aschbacher's program, but also in giving new insight into the relative abundance of exotic examples, i.e. fusion systems not induced by any finite group. In the third part we attack a major problem in the algebraic theory of fusion systems by defining an analogue in fusion systems of centralizers of subgroups of finite groups. This will simultaneously facilitate a classification of fusion systems in the spirit of Aschbacher's program, and lead to a combinatorial understanding of maps between classifying spaces of fusion systems.", "To": ["2018-07-31, Grant Agreement terminated |"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-08-01"], "Project_ID": ["707758"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["How single DNA polymerases make decisions during proofreading"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["DNA Pol III"], "Technology_Description": "DNA polymerases (DNA Pols) make various decisions during DNA replication. Decisions regarding nucleotide selection, lesion bypass and how to respond to replication errors are a few important examples. During replication, DNA Pols can synthesize DNA at remarkable rates, e.g. 1,000 bp/s for E. Coli DNA Pol III. However, errors can be introduced during replication, resulting in a terminal DNA mismatch. Mismatches can then be sensed and removed by action of the 3\u2019 to 5\u2019 exonuclease activity of the DNA Pol. How DNA Pols can sense mismatches to initiate proofreading and how the primer strand migrates into the exonuclease domain, often a distance of 30 \u00c5, is the focus of this proposal. Moreover, this research aims to understand mechanisms of proofreading in higher complexity DNA Pol assemblies at single-molecule resolution. Proofreading will be studied with the model enzyme E. Coli DNA Pol III, consisting of separate protein subunits that assemble to form a higher order complex, namely the polymerase, exonuclease and the \u03b22-clamp, which is a processivity factor that encircles the DNA and increases the affinity of the polymerase to the DNA. The proposed work will employ single-molecule FRET in order to evaluate proofreading dynamics at high spatial and temporal resolution. Three main objectives will be performed in order to understand (1) how DNA mismatches initiate proofreading (2) how mutations within the exonuclease domain affect proofreading and (3) how DNA lesions can influence proofreading as a function of position within the DNA template. These objectives will be achieved with a single-molecule FRET assay containing fluorescently labelled DNA to monitor proofreading dynamics in real time. This work will shift the knowledge frontier by advancing our understanding of proofreading during DNA replication in order to better realise the relationship between DNA mutations and the development of human diseases like cancer.", "To": ["2018-03-31, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-04-01"], "Project_ID": ["705015"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSIDAD DE ZARAGOZA", "UNIVERSITEIT GENT", "ASTON UNIVERSITY", "UNIVERSITAET HOHENHEIM", "STOCKHOLMS UNIVERSITET", "QUEEN MARY UNIVERSITY OF LONDON", "THE UNIVERSITY OF EDINBURGH", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.", "ORGANICS LIMITED", "AVA GREEN CHEMISTRY DEVELOPMENT GMBH"], "EU_Contribution": ["EUR 3 623 830,56"], "Project_Title": ["Advanced Carbon Materials from Biowaste: Sustainable Pathways to Drive Innovative Green Technologies"], "Total_Cost": ["EUR 3 623 830,56"], "Country": ["Spain", "Belgium", "United Kingdom", "Germany", "Sweden", "United Kingdom", "United Kingdom", "Germany", "United Kingdom", "Germany"], "Project_ACR": ["GreenCarbon"], "Technology_Description": "The energy crisis, environmental pollution and global warming are serious problems that are of great concern throughout the world. Around 40% of the world\u2019s energy consumption is dedicated to the production of materials and chemicals. Thus, there is a need to develop high-performance materials based on renewable resources, simpler to synthesise and cost effective. Carbon materials derived from renewable resources (e.g., biomass) are ideal candidates to meet these needs. The main objective of our proposed Innovative Training Network is to develop new scientific knowledge, capability, technology, and commercial products for biomass-derived carbons (BCs); thus impacting the way that Europe uses and innovates with sustainable carbon materials. This will be accomplished through outstanding research and training programmes for fourteen early-stage researchers (ESRs). Our proposed research programme is feasible given the varied expertise and knowledge of the academic and industrial participants. We expect that GreenCarbon will improve our ability to rationally design a range of functionalised BC-derived materials using different individual and synergistically coupled processes and expand their practical applications. Our research programme comprehensively covers all aspects from precursors (the nature of biomass) to processing (thermochemical conversion, porosity development, chemical functionalisation) and application (e.g., CO2 capture, heterogeneous catalysis and chemicals from biomass) enabling a unique design of engineered sustainable BC materials. At the same time, our training programme is designed with the aim to empower the ESRs through the provision of a comprehensive and coherent training package, which includes complementary competencies and knowledge in all the science, engineering and business skills so as to be capable of deploying new technologies within different environments both inside and outside of academia.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-10-01"], "Project_ID": ["721991"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["UMEA UNIVERSITET", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "OREBRO UNIVERSITY", "BEN-GURION UNIVERSITY OF THE NEGEV", "UNIVERSITY OF THE WEST OF ENGLAND, BRISTOL", "UNIVERSITAET HAMBURG", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V."], "EU_Contribution": ["EUR 3 874 726,44"], "Project_Title": ["SOcial Cognitive Robotics in The European Society"], "Total_Cost": ["EUR 3 874 726,44"], "Country": ["Sweden", "Spain", "Sweden", "Israel", "United Kingdom", "Germany", "Germany"], "Project_ACR": ["SOCRATES"], "Technology_Description": "SOCRATES is a PhD training program for 15 young researchers, created to develop the field of Social Robotics with an application focus on Robotics in Eldercare. ", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2016-11-01"], "Project_ID": ["721619"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["PARTNERSHIP FOR ADVANCED COMPUTINGIN EUROPE AISBL", "EUROPEAN TECHNOLOGY PLATFORM FOR HIGH PERFORMANCE COMPUTING"], "EU_Contribution": ["EUR 2 551 875"], "Project_Title": ["European eXtreme Data and Computing Initiative"], "Total_Cost": ["EUR 2 551 875"], "Country": ["Belgium", "Netherlands"], "Project_ACR": ["EXDCI"], "Technology_Description": "The three most significant HPC bodies in Europe, PRACE, ETP4HPC and EESI, have come together within EXDCI to coordinate the strategy of the European HPC Ecosystem in order to deliver its objectives. In particular, the project will harmonize the road-mapping and performance monitoring activities of the ecosystem to produce tools for coherent strategy-making and its implementation by:", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["FETHPC-2-2014 - HPC Ecosystem Development"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Belgium"], "Activity": ["Other", "Other"], "From": ["2015-09-01"], "Project_ID": ["671558"], "Call_for_Proposal": ["H2020-FETHPC-2014"]}, -{"Partners": ["STICHTING KATHOLIEKE UNIVERSITEIT", "STICHTING KATHOLIEKE UNIVERSITEIT"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Commercialising a novel diagnostic panel for patient stratification in Age-related MACULAr Degeneration"], "Total_Cost": ["EUR 150 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["MACULA2"], "Technology_Description": "In MACULA2 we aim to develop a genetic diagnostic test for complement activation that will allow proper stratification of patients with age-related macular degeneration (AMD). AMD is an inflammatory disease, the #1 cause of blindness in the world, with 196 million patients estimated for 2020. Such a test does not currently exist, strongly hampering drug development and patient treatment. Poor patient stratification contributes to high failure rates in trials for AMD. Local and systemic inflammation in AMD are caused by deregulated activation of the alternative pathway of the complement system. In AMD, some patients have higher complement activation levels compared to controls, which stimulates further inflammation. Several complement-lowering therapies for AMD are under development. Pharmaceutical companies are aware that patients with a genetic predisposition to higher complement activation levels will potentially benefit most from such treatments. Without sound patient stratification, therapies that are currently in clinical trials may not reach the statistical significance needed for approval. However, certain individuals might actually benefit from these therapies because of their specific genetic makeup. We aim to solve the challenge of patient stratification in AMD by developing a novel diagnostic test based on genetic testing combined with a patient questionnaire. An AMD diagnostic test will contribute towards a precision medicine approach towards treatment of patients.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["737607"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.", "LOUGHBOROUGH UNIVERSITY", "UNIVERZA V LJUBLJANI", "FUNDACION CENER-CIEMAT", "POLYMER COMPETENCE CENTER LEOBEN GMBH", "ACCADEMIA EUROPEA DI BOLZANO", "ELECTRICITE DE FRANCE", "KENERGIA SVILUPPO SRL"], "EU_Contribution": ["EUR 3 576 247,56"], "Project_Title": ["Photovoltaic module life time forecast and evaluation"], "Total_Cost": ["EUR 3 576 247,56"], "Country": ["Germany", "United Kingdom", "Slovenia", "Spain", "Austria", "Italy", "France", "Italy"], "Project_ACR": ["SOLAR-TRAIN"], "Technology_Description": "The quality assurance in the photovoltaic industry is yet in its infancy, requiring both underpinning science and trained personnel to reduce costs of energy. An unmet industrial requirement is an accelerated, and operating environment specific, service life time and energy yield assessment. SOLAR-TRAIN will qualify ESRs in the field of PV durability as part of a highly innovative, multi-disciplinary project meeting industry requirements. The objective is to develop novel, validated models for the service life time and energy prediction of PV modules and systems. The elements to this puzzle are researched in the frame of 14 PhD projects with individual areas of focus, such as (a) climatic degradation factors, (b) system analytics, (c) material (polymer) parameters, (d) service life & energy models, (e) linking production to performance and (f) performance enhancement by improved O&M. Commercial and test samples will be produced and tested in the distributed measurement campaign during this project. They will be exposed to state-of-the-art and to-be-developed stress cycles to allow a validated link of degradation to stresses, production methods, materials and methods of deployment. Accelerated and lower cost test cycles for the assessment of innovative materials and module developments will be delivered. The project is integrated both in terms of research as well as training. This inter-sectoral approach provides excellent theoretical and technical background as well as immersion in different business sectors and career mentoring, allowing ESRs to build up a sustainable professional network across Europe. For a most effective cross-sectoral training, the project\u2019s beneficiaries and partners represent the entire value chain, from materials developers / manufacturers through to operators and insurance companies. SOLAR-TRAIN will deliver on the targets stated in Issue Paper No. 2 of the SET Plan to maintain and strengthen PV leadership in Europe.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-09-01"], "Project_ID": ["721452"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["KAROLINSKA INSTITUTET"], "EU_Contribution": ["EUR 173 857,20"], "Project_Title": ["A multifunctional self-immolative hydrogel for accelerating the healing of chronic wounds"], "Total_Cost": ["EUR 173 857,20"], "Country": ["Sweden"], "Project_ACR": ["Multi-SIP Hydrogel"], "Technology_Description": "In this Marie Sk\u0142odowska-Curie Fellowship project entitled \u201cMulti-SIP Hydrogel\u201d I will design a modular synthetic platform for preparing multifunctional self-immolative polymer (SIP) hydrogels designed to accelerate tissue regeneration in chronic skin wounds. The hydrogels will contain multiple SIP components, each designed to rapidly degrade and deliver a therapeutic payload in response to a specific biochemical stimulus typical of a chronic wound (e.g., reactive oxygen species or enzymatic action). During the two years of this Fellowship, I aim to establish a proof-of-principle SIP-hydrogel system that will undergo sequential stimuli-responsive degradation and promote cell proliferation in vitro. This Fellowship will be undertaken under the supervision of Prof. Molly Stevens in the Division of Biomaterials and Regenerative Medicine at the Karolinska Institute (KI), which has the world-leading expertise in polymer chemistry, biomaterials engineering, cell biology and tissue engineering crucial to the objectives of the proposed work plan. Due to the modular design of the \"Multi-SIP Hydrogel\" platform, there is broad scope for designing SIP-hydrogels matched to different tissue types once a proof-of-principle is established. This will initiate new research areas at the cutting edge of biomaterials science, which will help me to establish my own independent research career following the proposed Fellowship.", "To": ["2019-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-02-01"], "Project_ID": ["705475"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Towards a Reliable Model for Dark Matter Search Experiments"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SABRE"], "Technology_Description": "There is ample evidence that our Milky Way is embedded in a halo of Dark Matter. While the sun is revolving around the galactic center, it moves through this halo resulting in a constant Dark Matter wind on earth. The revolution of the earth around the sun produces then an annual modulation of the intensity of this wind. Dark Matter detection experiments have produced contradicting results so far. While the DAMA/LIBRA experiment reports the measurement of an annual modulation consistent with a Dark Matter signal, other experiments have not seen an interaction so far. The SABRE experiment aims to shed light on this controversy by detecting the annual modulation in the same target material as DAMA but with improved the sensitivity and using twin detectors in the northern and southern hemispheres. SABRE is currently preparing for a proof of principle at the same underground laboratory in Italy where DAMA operates, and will upgrade afterwards to the full-scale experiment.", "To": ["2018-06-30, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-07-01"], "Project_ID": ["703650"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITEIT GENT", "TECHNISCHE UNIVERSITEIT DELFT", "RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN", "VYSOKA SKOLA CHEMICKO-TECHNOLOGICKA V PRAZE", "UNIVERSITAT POLITECNICA DE CATALUNYA"], "EU_Contribution": ["EUR 3 715 183,44"], "Project_Title": ["Sustainable Product, Energy and Resource Recovery from Wastewater"], "Total_Cost": ["EUR 3 715 183,44"], "Country": ["Belgium", "Netherlands", "Germany", "Czech Republic", "Spain"], "Project_ACR": ["SuPER-W"], "Technology_Description": "In many cases energy, water and resources contained in wastewater may have significant value if recovered. Therefore, the EU is currently confronted with a paradigm shift from wastewater treatment to resource recovery. To facilitate this shift, the SuPER-W European Joint Doctorate programme trains early-stage researchers (ESRs) in developing technologies for water, energy, nutrient and metal reuse, and bioproduction from (waste)water. The ESRs obtain knowledge and skills needed to turn environmental problems into economic opportunities. SuPER-W focuses not only on technology development through research, but the ESRs are also trained in translating research into policy, creative problem-solving, identification of bottlenecks for effective implementation of resource recovery technologies, development of business cases and urban/industrial ecosystems, and assessment of sustainability and the role of public perception and policy in innovation. Furthermore, they acquire a set of commercial, entrepreneurial and managerial skills that prepare them as future leaders. All ESRs are supervised by at least 2 promoters from 2 universities and co-supervised by a researcher from a non-academic partner organisation. Moreover, they conduct an internship in the non-academic sector in the first and last project year, contributing to more effective dissemination and exploitation of their research results. To organise the training, SuPER-W brings together leading researchers from 5 renowned universities and 12 associated non-academic partner organisations, including industrial partners involved in technology development, SMEs focused on consultancy/engineering, a service provider, a government agency, and professional network organisations. ESRs who successfully defend the PhD thesis and finish the doctoral training programme receive a double or joint PhD degree, jointly awarded by the universities of his/her promoters, as well as a joint doctoral training certificate of SuPER-W.", "To": ["2020-02-29, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-EJD - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-EJD)"], "Funding_scheme": ["MSCA-ITN-EJD - European Joint Doctorates"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["676070"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN", "RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Semiconductor-based quantum network"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["SEQUNET"], "Technology_Description": "Quantum networking would enable the connection of quantum processing nodes to increase computing power, long distance intrinsically secure communication, and the sharing of quantum resources over wide networks. Fully realizing these prospects requires local nodes with many coupled qubits connected by photonic links. Currently, qubits with good prospects for scaling to large numbers provide no optical interface, while optically addressable systems appear difficult to scale. This project aims to establish the fundamentals for quantum networks consisting of potentially scalable semiconductor spin qubits in gated GaAs quantum dots. These electrically controlled qubits have been proven viable for quantum computing, but so far have not been interfaced coherently with photons.", "To": ["2021-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["679342"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM", "STICHTING KATHOLIEKE UNIVERSITEIT"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["Large-scale cortical communication: Brain oscillatory mechanisms of attention allocation and selective inhibition"], "Total_Cost": ["EUR 165 599,30"], "Country": ["United Kingdom", "Netherlands"], "Project_ACR": ["BrainCrossTalk"], "Technology_Description": "This research proposal aims to identify basic mechanisms of local and global communication within the human brain enabling dynamic information processing. Specifically, I will investigate how the human brain allocates cognitive resources (via selective attention and inhibition) and therefore, dynamically engages and disengages frontal and posterior cortical areas. Several oscillatory mechanisms have been proposed to orchestrate such local and global cortical communication. While there are theoretical models hypothesising such mechanisms (i.e. gating by inhibition and cognitive resource allocation), to date no systematic empirical investigation of the interaction between these mechanisms exists. The current proposal aims at filling this gap by investigating the interaction \u2013 and the complexity thereof \u2013 between the neuronal mechanisms of different cognitive operations when they need to be integrated. The results will therefore serve to establish a common framework that links individual mechanisms and maps their interactions in the human brain.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["703456"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "THE UNIVERSITY OF EXETER", "KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 1 999 555"], "Project_Title": ["The makeup of the modern horse: a history of the biological changes introduced by human management"], "Total_Cost": ["EUR 1 999 555"], "Country": ["France", "France", "United Kingdom", "Denmark"], "Project_ACR": ["PEGASUS"], "Technology_Description": "The horse provided us with rapid transportation, an almost unrivaled secondary product that tremendously impacted the politico-economical trajectory of our societies, revolutionizing the circulation of ideas, people, languages, religions and communication. Horse chariotry and cavalry also changed warfare and beyond the battlefield new equestrian technologies have stimulated agricultural productivity. However, the 5,500 year long history of horse domestication and management, which transformed the natural evolutionary trajectory of wild horses into the more than 625 domestic breeds living today, is difficult to reconstruct from archaeology, history and modern genetics alone. Yet, with archaeogenetics, one can access the genetic information from past individuals and track in great detail past population trajectories. In this project, I propose to build on the latest advances in the analysis of ancient DNA molecules to gather new genomic, epigenomic and metagenomic information from ancient horses. This will be integrated with archaeozoological, isotopic and historical data to enhance our understanding of the multiple processes underlying the transformation of the animal that perhaps most impacted our history. Starting from the characterization of pre-domestic populations of wild horses, I will evaluate the genomic and dietary impact of early domestication stages and will explore whether horses were independently domesticated in Iberia and the Pontic-Caspian steppe. I will follow how the emergence of chariotry and the development of heavy cavalry impacted the horse\u2019s behavioural, physiological and biological makeup. I will reveal the horse characteristics that were preferred in various historical contexts and will investigate a diversity of management strategies and husbandry conditions to reveal their impact on horses, from classical and late antique periods until the recent creation of modern breeds by means of intensive selective breeding.", "To": ["2021-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-12-01"], "Project_ID": ["681605"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["FORSCHUNGSZENTRUM JULICH GMBH", "FORSCHUNGSZENTRUM JULICH GMBH", "RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN", "UNIVERSITA DEGLI STUDI DI FERRARA"], "EU_Contribution": ["EUR 2 379 276"], "Project_Title": ["Search for electric dipole moments using storage rings"], "Total_Cost": ["EUR 2 379 276"], "Country": ["Germany", "Germany", "Germany", "Italy"], "Project_ACR": ["srEDM"], "Technology_Description": "One of the great mysteries in the natural sciences is the dominance of matter over antimatter in the universe. According to our present understanding, the early universe contained the same amount of matter and antimatter. If the universe had behaved symmetrically as it developed, every particle would have been annihilated by one of its antiparticles. We therefore owe our very existence to mechanisms that have led to a world where something that we call matter remains. We propose to study such mechanisms by searching for electric dipole moments (EDMs) of charged hadrons in a new class of precision storage rings. Our project will lay the foundations for a new European flagship research infrastructure. The breaking of the combined charge conjugation and parity symmetries (CP-violation) in the Standard Model is not strong enough to explain the observed excess of matter and further sources of CP-violation must be sought. These sources could manifest themselves in Electric Dipole Moments of elementary particles, which occur when the centroids of positive and negative charges are mutually and permanently displaced. The observation of an electric dipole moment will elucidate the mechanisms which led to the matter that dominates the universe. Although the measurement principle, the time development of the polarization vector subject to a perpendicular electric field, is simple, the smallness of the effect makes this an enormously challenging project. This can only be mastered through the common effort of an international team of accelerator and particle physicists, working closely with engineers. The proponents of this design study and the research environment at the Forschungszentrum J\u00fclich (Germany), including the conventional storage ring COSY, provide the optimal basis for one of the most spectacular possibilities in modern science: finding an EDM as a signal for new physics beyond the Standard Model and perhaps explaining the puzzle of our existence.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["694340"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN", "RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN"], "EU_Contribution": ["EUR 2 499 884"], "Project_Title": ["Multi-Scale Description of Non-Universal Behavior in Turbulent Combustion"], "Total_Cost": ["EUR 2 499 884"], "Country": ["Germany", "Germany"], "Project_ACR": ["MILESTONE"], "Technology_Description": "Combustion is an extremely important field for our society. The development of new, step-change technologies is essential and greatly benefits from computational design. However, turbulent combustion physics are complex, highly non-linear, of multi-scale and multi-physics nature, and involve interactions at many time-scales. This makes modeling quite challenging such that accurate predictive models, especially for the formation of pollutants, are not available. Today, the two major challenges for developing predictive simulations of turbulent combustion are first to account for its multi-scale nature by considering the non-universal behavior of small-scale turbulence, which is known to be critically important for turbulence-chemistry interactions, and second, to provide data in sufficient detail for rigorous analysis of model deficiencies and unambiguous model development. These two issues are addressed in the proposed work. The main overall objectives are: 1) Establish a new multi-scale framework to analyze and model turbulent combustion phenomena based on a new way to describe turbulence using so-called dissipation elements, which are space-filling regions in a scalar field allowing to capture its small-scale morphology and non-universality. 2) Create new unprecedented datasets using direct numerical simulations (DNS) and provide new analysis methods to develop and validate combustion models; this will include automatically reducing and optimizing chemical kinetic mechanisms for use in DNS and developing an on-the-fly chemistry reduction technique. 3) Apply new modeling approaches to complex and highly non-linear modeling questions, such as pollutant formation in turbulent spray combustion. The successful outcome of the project will provide new and unprecedented datasets, a quantitative description of the impact of non-universality in small-scale turbulence on different aspects of turbulent combustion, and the basis for an entirely new multi-scale closure.", "To": ["2021-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["695747"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["UNIVERSIDAD COMPLUTENSE DE MADRID"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Ireland and Late-Georgian British Imaginings of Belonging: With Particular Reference to William Wordsworth"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["ILBIB"], "Technology_Description": "Belonging \u2013 a concept at the heart of which lies a yearning for home \u2013 has domestic, regional, national, and even cosmopolitan implications. It was a particularly important concept in late-Georgian Britain (c. 1780-1830), during which time socio-political instabilities fostered an inward-looking impetus, prompting Britons to ask what home meant and what attachment to home entailed.", "To": ["2019-09-14, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-15"], "Project_ID": ["749888"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN", "RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN"], "EU_Contribution": ["EUR 1 786 563"], "Project_Title": ["Engineering Quantum Error Correction"], "Total_Cost": ["EUR 1 786 563"], "Country": ["Germany", "Germany"], "Project_ACR": ["EQEC"], "Technology_Description": "This proposal will advance the theory of quantum error correction towards its application in real physical devices, in particular superconducting transmon qubit systems. The research will result in proposals for experiments: how to use physical qubits to redundantly represent logical quantum information and how error information can be obtained and classically processed. The research will consider novel ways of using transmon qubits to achieve a universal fault-tolerant surface code architecture. The research will produce a design of a universal fault-tolerant architecture in which qubits are encoded in the electromagnetic field of a (microwave) cavity. Research will also focus on mathematical and numerical studies in quantum error correction which are technology-independent, but shed light on coding overhead, decoding efficiency and logical universality.", "To": ["2021-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-04-01"], "Project_ID": ["682726"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["DANMARKS TEKNISKE UNIVERSITET", "BAYER TECHNOLOGY SERVICES GMBH", "Bayer AG", "UNIVERSITE LYON 1 CLAUDE BERNARD", "UNIVERSITY OF STRATHCLYDE", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "ALFA LAVAL COPENHAGEN A/S", "UNILEVER U.K. CENTRAL RESOURCES LIMITED", "RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN"], "EU_Contribution": ["EUR 4 090 249,44"], "Project_Title": ["Advancing Modelling for Process-Product Innovation, Optimization, Monitoring and Control in Life Science Industries"], "Total_Cost": ["EUR 4 090 249,44"], "Country": ["Denmark", "Germany", "Germany", "France", "United Kingdom", "United Kingdom", "Denmark", "United Kingdom", "Germany"], "Project_ACR": ["ModLife"], "Technology_Description": "The ModLife project is a European Training Network initiative that brings together 5 leading European universities, 4 global industrial players and 2 SMEs to undertake research and training in the area of product-process innovation, optimization monitoring and control for life sciences and biotechnology industries. Modlife aims to develop Advanced Model-Based Optimization, Monitoring and Control as Enabling Technologies for bioprocess-product development and innovation tailored for the needs in life science industries. ModLife ETN will address excellence in research and training of next generation biochemical and process engineers in life sciences industries through: (1) Offering comprehensive training and knowledge transfer opportunities in multidisciplinary and multi-sectoral fields for training early stage researchers with multidisciplinary knowledge and competences bridging engineering and life sciences (2) Integrating and creating synergies among individually excellent but otherwise fragmented bioprocess engineering research centers across the European union in life sciences and biotechnology industries, (3) Building on advances in modeling and simulation, to develop cutting edge model-based enabling technologies and applications for optimization, monitoring and control for bioprocess and product development and innovation.", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2015-11-01"], "Project_ID": ["675251"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN", "RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN"], "EU_Contribution": ["EUR 1 491 875"], "Project_Title": ["Fundamental Studies in Catalysis \u2013 Reactivity Design with Experimental and Computational Tools"], "Total_Cost": ["EUR 1 491 875"], "Country": ["Germany", "Germany"], "Project_ACR": ["FunCatDesign"], "Technology_Description": "Catalysis is ubiquitous in modern academic and industrial chemistry as well as an integral and indispensable discipline that may contribute to solutions of current global challenges. While the field has grown significantly over the past few decades, with numerous transformations that were previously unthinkable now being possible, progress has frequently relied on serendipitous discoveries or elaborate screening efforts. Although it is indisputable that high-throughput screening is an extremely lucrative approach to generate a wealth of chemical information, the next frontier in the development of innovative approaches to meet the high demand for predictable, selective and sustainable processes will likely arise from fundamental insight. However, owing to the complexity of catalytic processes, the fleeting and frequently highly sensitive nature of intermediates and the associated challenges in gaining fundamental mechanistic understanding, insight-driven developments and especially reactivity designs have so far been extremely rare. The objective of this proposal is to capitalize on the tools of experimental and computational chemistry as a powerful means to gain access to the fundamental mechanistic details of key catalytic steps that are required to allow reactivity design. The specific subject for study will focus on the most significant challenges in nickel-catalysis - a highly promising area in the context of sustainability and synthetic diversity owing to nickel\u2019s relatively large abundance and also high reactivities towards relatively inert bonds. The proposed studies will address challenges in relation to Ni-catalyzed C-H activation, cross-coupling and trifluoromethylation reactions, as well as the exploration of novel avenues in catalysis at multinuclear sites.", "To": ["2020-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-05-01"], "Project_ID": ["637993"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN", "RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN"], "EU_Contribution": ["EUR 2 500 000"], "Project_Title": ["A Sequence Classification Framework for Human Language Technology"], "Total_Cost": ["EUR 2 500 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["SEQCLAS"], "Technology_Description": "This project will develop a unifying framework of novel methods for sequence classification and thus make a major break-through in automatic speech recognition and machine translation, advancing these areas of human language technology (HLT) beyond state-of-the-art. Despite the huge progress made in the field, the specific aspect of sequence classification has not been addressed adequately in the past research in these disciplines and remains a big challenge. The proposed project will provide a novel framework under consistent consideration of the leading aspect of sequence classification. It will break the ground for a deeper, more comprehensive foundation for sequence classification and pave the way for a new generation of algorithms that will put human language technology on a more solid basis and that will accelerate progress in the field across several disciplines. ", "To": ["2021-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-08-01"], "Project_ID": ["694537"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["CRANFIELD UNIVERSITY", "PANEPISTIMIO IOANNINON", "UNIVERSITA DEGLI STUDI DELLA CAMPANIA LUIGI VANVITELLI", "EXIS INNOVATION LTD"], "EU_Contribution": ["EUR 1 995 113"], "Project_Title": ["An Innovative Method for Improving the Structural Integrity using SMA Revolutionary Technology"], "Total_Cost": ["EUR 1 995 113"], "Country": ["United Kingdom", "Greece", "Italy", "United Kingdom"], "Project_ACR": ["InnoSMART"], "Technology_Description": "The project proposes to develop a revolutionary coating that will be able to alter and control the mechanical properties of materials by external stimuli. This novel coating will be able to contribute to the stiffness and rigidity of an elastic metallic structure, to withstand the expected loading conditions safely, to enhance the integrity of a damaged structure and at the same time to protect it from corrosion. Such coating can bring multiple breakthroughs from the design level to the maintenance and repair level of the structure. The innovative compounds of the proposed coating are elements of smart materials - Shape Memory Alloys (SMAs). SMA elements are designed materials that have one or more properties that can be significantly changed in a controlled fashion by external stimuli. They can sense temperatures or stress as a function of change in damping, stiffness, electrical resistivity and deflection. It is specifically the latter aspect, which makes SMAs highly interesting for the particular application, since it is the actuation function built into the material. The innovative concept of the coating is described briefly as follows: upon mechanical loading the structure and hence the coating are deformed together as a system. However, by heating the coating, the SMA elements tend to recover their experienced deformations and return to their original shape. At this point, shear forces will be developed to the interface between coating and structure. The developed shear forces are expected to mitigate the deformation of the structure and reduce the level of the stress field. The latter is a great benefit for the regions, where cracks exist, since the local reduction of the stress field will delay the crack propagation and hence the structural failure. Finally, the coating will be also followed by a system that will ensure a satisfactory cover of the metallic surface, as well as a module for assessing the effect of any structural defects that may exist.", "To": ["2018-06-30, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-1-2014 - FET-Open research projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-07-01"], "Project_ID": ["664892"], "Call_for_Proposal": ["H2020-FETOPEN-2014-2015-RIA"]}, -{"Partners": ["RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN", "RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN"], "EU_Contribution": ["EUR 1 988 750"], "Project_Title": ["Symbolic Analysis of Temporal and Functional Behavior of Networked Systems"], "Total_Cost": ["EUR 1 988 750"], "Country": ["Germany", "Germany"], "Project_ACR": ["SYMBIOSYS"], "Technology_Description": "The goal of SYMBIOSYS is to assure the reliability and interoperability of networked (software) systems, a crucial requirement in today\u2019s networked information society. To this end, we devise a software and systems analysis methodology that \u2013 for the first time \u2013 considers the vital influence factors that determine the behavior of networked systems, especially including input and temporal uncertainty of network interactions. With SYMBIOSYS, we will be able to automatically and effciently explore and analyze the vast amount of distributed execution paths in networked systems in a highly structured manner inspired by Symbolic Execution (SE).", "To": ["2020-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-08-01"], "Project_ID": ["647295"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["TECHNISCHE UNIVERSITEIT EINDHOVEN", "KATHOLIEKE UNIVERSITEIT LEUVEN", "RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN", "INCAS 3", "RIJKSUNIVERSITEIT GRONINGEN", "ANTEA NEDERLAND BV"], "EU_Contribution": ["EUR 3 632 486,25"], "Project_Title": ["Exploring the Unknown through Reincarnation and Co-evolution"], "Total_Cost": ["EUR 3 632 486,25"], "Country": ["Netherlands", "Belgium", "Germany", "Netherlands", "Netherlands", "Netherlands"], "Project_ACR": ["Phoenix"], "Technology_Description": "Humans have been exploring the world from the depths of the oceans to the edges of the universe. Yet many environments remain inaccessible, even to modern cutting-edge technology. Therefore problems like exploring the status of waste water under the Fukushima reactor, or discover suitable sites for underground CO2 storage remain unsolved.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-1-2014 - FET-Open research projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-10-01"], "Project_ID": ["665347"], "Call_for_Proposal": ["H2020-FETOPEN-2014-2015-RIA"]}, -{"Partners": ["CRANFIELD UNIVERSITY", "PANEPISTIMIO PATRON", "PANEPISTIMIO IOANNINON", "LULEA TEKNISKA UNIVERSITET", "EXIS INNOVATION LTD"], "EU_Contribution": ["EUR 2 495 863"], "Project_Title": ["An Advanced Methodology for the Inspection and Quantification of Damage on Aerospace Composites and Metals using an Innovative Approach"], "Total_Cost": ["EUR 2 495 863"], "Country": ["United Kingdom", "Greece", "Greece", "Sweden", "United Kingdom"], "Project_ACR": ["CompInnova"], "Technology_Description": "There is an innovative need for more efficient and reliable damage inspection, reducing time and cost of aircraft infrastructures, as well as maintenance-especially C and D Checks- without compromising the safety of passengers and goods transported. The CompInnova project is focused upon the development of an innovative inspection methodology, with automated and manual capabilities, for any type of composite and metallic aircraft structures. The novel structural integrity approach is comprised by three parts: a qualified Phased Array (PA) and Infrared Thermography (IRT) method attached to a mobile Vortex robot, a Damage Tolerance (DT) structural integrity assessment technique processed on a computer and an innovative repair system.", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-1-2014 - FET-Open research projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-09-01"], "Project_ID": ["665238"], "Call_for_Proposal": ["H2020-FETOPEN-2014-2015-RIA"]}, -{"Partners": ["PANEPISTIMIO IOANNINON"], "EU_Contribution": ["EUR 164 653,20"], "Project_Title": ["Location Based Suggestion of Keyword Queries"], "Total_Cost": ["EUR 164 653,20"], "Country": ["Greece"], "Project_ACR": ["LBSKQ"], "Technology_Description": "Query suggestion is a recent and important add-on feature of Web search engines (e.g., Google), which helps users to express their information needs precisely. Specifically, given the fact that the user may not be able to find appropriate keywords for her search, the system recommends to her a small set of keyword queries that are likely to match her original intention. As an example, when a user searches for \u201cconvertible car,\u201d she may miss all the documents indexed under \u201ccabriolet.\u201d Therefore, the engine suggests \u201ccabriolet\u201d as a follow-up query to the user. There has been extensive research in the past decade on effective query suggestion. However, none of the existing keyword query suggestion methods consider the user\u2019s location. We argue that the queries suggested to a user not only should be semantically relevant to her original query, but also should give results near the user\u2019s location, especially when these queries are expressed by a mobile user; otherwise, the suggested queries might not be of interest to the user. Therefore, there is a need for effective location-based keyword query suggestion (LBKQS) models. The objectives of this project are (1) the development of LBKQS models, (2) the evaluation of the proposed models, (3) the development of efficient and scalable LBKQS techniques based on the most effective models. In the end, we expect our system to provide appropriate query suggestions to mobile users in real-time.", "To": ["2017-03-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Greece"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-04-01"], "Project_ID": ["657347"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSIDAD DE SEVILLA"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Mastering the energetic particle distribution in a magnetohydrodynamic active plasma"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["FIREFELM"], "Technology_Description": "FIREFELM \u2013 fast ions, radial electric field and edge localized mode \u2013 is an interdisciplinary project aimed at getting a better understanding of the basic mechanisms responsible for the energetic particle transport in fusion as well as in astrophysical plasmas making use of advanced diagnostic systems and state-of-the-art numerical tools. The main goal of this proposal is to control the dynamics between energetic particles, radial electric fields and magnetohydrodynamic (MHD) perturbations in the plasma edge and its impact on the overall plasma confinement. The mechanisms underlying the fast ion transport induced by MHD instabilities, such as Edge Localized Modes (ELMs) and externally applied Magnetic Perturbations (MPs) will be studied through innovative diagnosis techniques developed at the University of Seville and the Centro Nacional de Aceleradores (CNA) in Seville, Spain and employed in different fusion devices such as ASDEX Upgrade (Germany) and MAST Upgrade (UK). This project consists of three main research lines which follow a bottom up approach: the first research line is dedicated to fusion technology and aims at the development of the new generation of fast ion loss detectors (FILDs). New FILD systems will be able to provide absolute fluxes of escaping ions, their poloidal distribution and critical information on the wave-particle momentum and energy exchange. These advanced FILDs will be employed to characterize the interdependence between fast ion losses and radial electric fields and to study the role of fast ions in plasma edge stability and in the ELM cycle. Unraveling the interaction between MHD instabilities and energetic particles in tokamak plasmas will advance our understanding of the observed particle acceleration and transport in the solar corona and help to identify similarities between tokamak and astrophysical plasmas. This third research line will shed light on the anomalous heating of the solar corona and generation of the solar wind.", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["708257"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN"], "EU_Contribution": ["EUR 257 860,80"], "Project_Title": ["Operator algebraic approach to topological phases"], "Total_Cost": ["EUR 257 860,80"], "Country": ["Germany"], "Project_ACR": ["OATP"], "Technology_Description": "Topologically ordered phases are a new state of matter, discovered only around the late '80s. In recent years interest in such states has sparked, one of the reasons being applications to topological quantum computing: the topological properties make the state robust against perturbations, making them ideal components in an environment where (thermal or other) noise is one's biggest enemy. By now there is a plethora of examples of topologically ordered states, whose only unifying feature seems to be that they do not fall into the Landau theory of phases. Although there are many examples, the mathematical framework to rigorously study such systems is less clear, in particular if one wants to consider both so-called long range entangled phases and symmetry protected phases. The goal of this project is to tackle this problem.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["657004"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITAT AUTONOMA DE BARCELONA", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "PANEPISTIMIO IOANNINON", "CHALMERS TEKNISKA HOEGSKOLA AB", "LEIBNIZ-INSTITUT FUER FESTKOERPER- UND WERKSTOFFFORSCHUNG DRESDEN E.V.", "VILNIAUS UNIVERSITETAS", "FAKULTET INZENJERSKIH NAUKA UNIVERZITETA U KRAGUJEVCU", "ISTITUTO NAZIONALE DI RICERCA METROLOGICA", "Happy Plating GmbH"], "EU_Contribution": ["EUR 3 274 969,68"], "Project_Title": ["Smart ELECTrodeposited Alloys for environmentally sustainable applications: from advanced protective coatings to micro/nano-robotic platforms"], "Total_Cost": ["EUR 3 274 969,68"], "Country": ["Spain", "United Kingdom", "Greece", "Sweden", "Germany", "Lithuania", "Serbia", "Italy", "Austria"], "Project_ACR": ["SELECTA"], "Technology_Description": "SELECTA is a highly inter-disciplinary initiative which has the primary goal of training young researchers in the field of smart electrodeposited metallic alloys suitable for environmental / sustainable development applications. The Network encompasses the fabrication and in-depth characterization of: (i) innovative protective coatings, (ii) resilient micro/nano-electromechanical systems, and (iii) wirelessly actuated micro/nano-robotic platforms for cutting-edge environmental applications. The project will explore new types of electrodeposited alloys (based on Fe, Cu or Al; free from hazardous and scarce raw elements), with tunable structure (amorphous, nanocrystalline), morphology (dense, nanoporous) and geometry (films, micropillars, nanowires), to meet specific technological demands (high wear/corrosion resistance, superior magnetic properties or hydrophobicity). SELECTA aims to integrate technological progress with environmental sustainability concerns, which is one of the major \u201cSocietal Challenges\u201d listed in the Horizon 2020 Work Programme. Several disciplines (Physics, Electrochemistry, Engineering, Environmental Sciences, Biology and Robotics) converge together to provide a holistic approach to accomplish the SELECTA goals. The project brings together 10 Beneficiaries and 7 Partner Organizations (including 5 private companies), belonging to 10 EU Member States (plus Switzerland and Serbia). Special efforts will be devoted to bridge fundamental science with commercialisation of the research outcome. The complementarities among partners will render a high-level, multi-faceted educational programme. World-class research will be combined with unique training opportunities in soft skills, such as career planning, dissemination, intellectual property rights, entrepreneurship or management. The Network aims to provide highly-qualified specialists able to face future professional challenges in either Academia or Industry in an independent manner.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Paolo Antonio Mastroeni", "Tel.: +39-011-3919541", "Fax: +39-011-346384", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["642642"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["PANEPISTIMIO IOANNINON"], "EU_Contribution": ["EUR 168 391,80"], "Project_Title": ["Identity matching from still images without face information"], "Total_Cost": ["EUR 168 391,80"], "Country": ["Greece"], "Project_ACR": ["StillNoFace"], "Technology_Description": "In computer vision, human identity matching from images and/or video has been an active research topic for more than two decades and its popularity is increasing with the increase in computing power. The state of the art techniques are based on face images and gait recognition from long video sequences. However, in many real applications only some static images of the subject may be available where face information is missing (e.g. posterior views). These scenarios have not been addressed by the research community as they are difficult to handle. In this action, we propose a method for matching identities from a set of 2D images of a person without any facial information. The method consists of two steps: at first, the human body is modelled by a 3D articulated model whose pose is estimated by its 2D projections onto the images. Then, biometric features are computed by fitting 3D deformable models to the image data, thus capturing the form and size of the main parts of the anatomy. The overall framework works under a probabilistic framework, with a learning step, in order to encode pose and anatomy variations between a set of individuals that are to be identified.", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Greece"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["656094"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITAET BREMEN", "UNIVERSITAET BREMEN"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Surface modulation of wounds: heal by inhalants!Novel drug-based treatment for excessive scars and chronic wounds."], "Total_Cost": ["EUR 150 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["SUMOWO"], "Technology_Description": "The innovative concept of the ERC Starting Grant project \u201cKeratinocytes and Matrix metalloproteinases: driving force of skin wound contraction?\u201d was to use inhalants for skin wounds and it proved to be excellent and functional. Surface Modulation of Wounds (SUMOWO) with these anti-inflammatory, pro-migratory and anti-fibrotic compounds will be beneficial for chronic wound healing and reduce excessive scarring. This novel drug-based treatment strategy marks a novel era of wound care. A clinical phase 1 study on healthy volunteers is planned to show the product\u2019s safety and tolerability for skin use \u2013 the first step towards clinical application. The goal of SUMOWO is to deliver clinical proof of concept, to provide a thorough market analysis with contact to key-players, to secure our intellectual property rights on an international platform, to accelerate commercial exploitation and ultimately, to restore patients\u2019 life quality.", "To": ["2017-12-31, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2015 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["693017"], "Call_for_Proposal": ["ERC-2015-PoC"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI TORINO", "POLITECNICO DI TORINO", "UNIVERSITAT POLITECNICA DE VALENCIA", "AALBORG UNIVERSITET", "PANEPISTIMIO IOANNINON", "ACEA PINEROLESE INDUSTRIALE SPA", "LIQTECH AS"], "EU_Contribution": ["EUR 630 000"], "Project_Title": ["Enhancing water quality by developing novel materials for organic pollutant removal in tertiary water treatments"], "Total_Cost": ["EUR 630 000"], "Country": ["Italy", "Italy", "Spain", "Denmark", "Greece", "Italy", "Denmark"], "Project_ACR": ["MAT4TREAT"], "Technology_Description": "The MAT4TREAT project consists in a consortium of 8 Universities, 5 of them European (UNITO, AAU, POLITO, UPV and UOI), and the other three from outside the EU (UNLP, McGill, SU), as well as two non academic institutions (ACEA and LQT). These groups are committed to work in the development of novel materials to be used in innovative integrated water tertiary treatments (to remove, for instance, Emerging Pollutants). This ambitious goal will be achieved by world leading research groups in the following fields: (i) graphene-based and other carbon-related materials, (ii) polymeric materials, (iii) oxidic ceramic materials, and (iv) hybrid inorganic-polymeric materials. ", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["645551"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["THE CYPRUS INSTITUTE", "BERGISCHE UNIVERSITAET WUPPERTAL", "RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN", "TECHNISCHE UNIVERSITEIT EINDHOVEN", "UNIVERSITY OF CYPRUS", "UNIVERSITA DEGLI STUDI DI FERRARA", "UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA"], "EU_Contribution": ["EUR 3 723 916,32"], "Project_Title": ["High Performance Computing in Life Sciences, Engineering And Physics"], "Total_Cost": ["EUR 3 723 916,32"], "Country": ["Cyprus", "Germany", "Germany", "Netherlands", "Cyprus", "Italy", "Italy"], "Project_ACR": ["HPC-LEAP"], "Technology_Description": "Progress in computers and algorithms in the last years has made numerical simulation and modelling a key research methodology in both academia and industry, which in turn drives exascale computing in order to maintain excellence in research and innovation. A disruptive evolution in computer technologies is required for attaining exascale performances in the coming years bringing challenges that urgently need to be addressed across science and engineering fields. Therefore new interdisciplinary strategies are required in order to educate the next generation of scientists to address such challenges enabling them to be at the forefront of their respective research fields. Instead of the traditional domain-specific training, integrated approaches are needed that can be best implemented by collaborative networks of universities, research institutes and industrial partners. We propose a highly interdisciplinary joint doctorate program realized by bringing together world-leading experts in applied mathematics, high performance computing technologies, particle and nuclear physics, fluid dynamics and life sciences to appropriately train researchers in Europe to exploit high performance computing, advance science and promote innovation. Students will be trained in mathematical and computational concepts underpinning current and future numerical simulations in turbulent flows, computational biology and lattice quantum chromodynamics. The research projects are designed to enhance collaborations and interactions across these disciplines, integrating non-academic partners, and to develop methodologies that efficiently use large-scale numerical simulations on future high performance computer systems. Students who complete this training program will be versatile to undertake highly interdisciplinary projects, well positioned to embark on a successful career in academia or the industrial sector.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-EJD - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-EJD)"], "Funding_scheme": ["MSCA-ITN-EJD - European Joint Doctorates"], "Coordinated_in": ["Cyprus"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-04-01"], "Project_ID": ["642069"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["UNIVERSITY OF BATH", "UNIVERSITY OF BATH"], "EU_Contribution": ["EUR 789 823,77"], "Project_Title": ["Externally Tuneable Separations for Membrane Reactors"], "Total_Cost": ["EUR 789 823,77"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["TUNEMEM"], "Technology_Description": "I will develop an all new type of reactor for pharmaceutical and chemical process applications \u2013 the \u2018tuneable membrane reactor\u2019. These contain ground-breaking conducting polymer composite membranes that will allow in-situ tuning of the molecular selectivity for both neutral and charged species through them. This is revolutionary: current state-of-the-art membranes can be electrically tuned for charged species only. The project is timely, developing a new technology that can give the EU a competitive advantage for our declining pharmaceutical and (petro)chemical manufacturing base and builds on my recent research innovations.", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-08-01"], "Project_ID": ["646769"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["KATHOLIEKE UNIVERSITEIT LEUVEN", "HELSINGIN YLIOPISTO", "RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN", "KUNGLIGA TEKNISKA HOEGSKOLAN", "NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA", "TARTU ULIKOOL", "MEAB CHEMIE TECHNIK GMBH", "MYTILINEOS ANONIMI ETAIRIA - OMILOS EPICHEIRISEON", "ALOUMINION TIS ELLADOS VIOMICHANIKI KAI EMPORIKI ANONYMOS ETAIREIA VEAE", "TITAN CEMENT COMPANY AE"], "EU_Contribution": ["EUR 3 720 893,40"], "Project_Title": ["European Training Network for Zero-waste Valorisation of Bauxite Residue (Red Mud)"], "Total_Cost": ["EUR 3 720 893,40"], "Country": ["Belgium", "Finland", "Germany", "Sweden", "Greece", "Estonia", "Germany", "Greece", "Greece", "Greece"], "Project_ACR": ["REDMUD"], "Technology_Description": "To tackle its (critical) raw material dependency, Europe needs comprehensive strategies based on sustainable primary mining, substitution and recycling. Freshly produced flows and stocks of landfilled industrial residues such as mine tailings, non-ferrous slag and bauxite residue (BR) can provide major amounts of critical metals and, concurrently, minerals for low-carbon building materials. The European Training Network for Zero-Waste Valorisation of Bauxite Residue (REDMUD) therefore targets the vast streams of new and stockpiled BR in the EU-28. BR contains several critical metals, is associated with a substantial management cost, whereas spills have led to major environmental incidents, including the Ajka disaster in Hungary. To date, zero-waste valorisation of BR is not occurring yet. The creation of a zero-waste BR valorisation industry in Europe urgently requires skilled scientists and engineers, who can tackle the barriers to develop fully closed-loop environmentally-friendly recovery flow sheets. REDMUD trains 15 researchers in the S/T of bauxite residue valorisation, with emphasis on the recovery of Fe, Al, Ti and rare earths (incl. Sc) while valorising the residuals into building materials. An intersectoral and interdisciplinary collaboration of EU-leading institutes and scientists has been established, which covers the full value chain, from BR to recovered metals and new building materials. Research challenges include the development of efficient extraction of Fe, Al, Ti and rare earths (incl. Sc) from distinct (NORM classified) BRs and the preparation of new building materials with higher than usual Fe content. By training the researchers in pyro-, hydro- and ionometallurgy, electrolysis, rare-earth extraction and separation technology, inorganic polymer and cement chemistry, Life Cycle Assessment (LCA), NORM aspects and characterisation, they become the much needed scientists and engineers for the growing European critical raw materials industry.", "To": ["2018-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2014-12-01"], "Project_ID": ["636876"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION", "UNIVERSITAET STUTTGART", "FORSCHUNGSZENTRUM JULICH GMBH", "NUMERICAL ALGORITHMS GROUP LTD", "RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN", "TERATEC"], "EU_Contribution": ["EUR 4 048 845"], "Project_Title": ["Performance Optimisation and Productivity"], "Total_Cost": ["EUR 4 048 845"], "Country": ["Spain", "Germany", "Germany", "United Kingdom", "Germany", "France"], "Project_ACR": ["POP"], "Technology_Description": "High performance Computing is becoming a fundamental tool for the progress of science and engineering and as such for economic competitiveness. The growing complexity of parallel computers is leading to a situation where code owners and users are not aware of the detailed issues affecting the performance of their applications. The result is often an inefficient use of the infrastructures. Even when the need to get further performance and efficiency is perceived, code developers may not have sufficient insight on its detailed causes for addressing the problem properly. This may lead to blind attempts to restructure codes and consequent lack of efficiency. ", "To": ["2018-03-31, ongoing project"], "Meta": [""], "Topic_s": ["EINFRA-5-2015 - Centres of Excellence for computing applications"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Other", "Higher or Secondary Education Establishments", "Other"], "From": ["2015-10-01"], "Project_ID": ["676553"], "Call_for_Proposal": ["H2020-EINFRA-2015-1"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM", "AnalytiCon Discovery GmbH", "MERCACHEM BV"], "EU_Contribution": ["EUR 1 565 180,58"], "Project_Title": ["Delivering Better Starting Points for Drug Discovery: New Compound Libraries Driven By Intelligent Design"], "Total_Cost": ["EUR 1 565 180,58"], "Country": ["United Kingdom", "Germany", "Netherlands"], "Project_ACR": ["iDESIGN"], "Technology_Description": "Whilst the need to generate new therapeutics has never been more important, drug discovery is at the same time becoming much more difficult. In short, we need to be more efficient at developing drugs. One way of achieving this is to reduce the attrition rates, which currently blight the drug-discovery process, by populating compound screening libraries with more structurally diverse and higher quality, i.e. designed, molecules to provide better starting points for drug development. Pharma also needs a new type of researcher given an increasing proportion of scientists are now finding employment in smaller companies, where they need to be more flexible, entrepreneurial and business-aware. iDESIGN seeks to address these key challenges by combining the complementary expertise from both academic and industrial sectors. iDESIGN has the following Principal Objectives: 1) to use the ESRs' individual research projects to develop new, structurally diverse, 'smart' compound libraries for the sector to use in hit-identification screening campaigns; 2) to provide a training programme which will see the ESRs becoming expert synthetic and medicinal chemists, confident research scientists, consummate professionals, effective communicators and innovators with a creative and entrepreneurial spirit. iDESIGN will begin with an academic training phase, during which the ESRs will undertake project-wide training whilst acquiring the synthesis skills to generate bespoke molecular scaffolds, which they will elaborate and validate using in silico and experimental methods. The ESRs will then transfer to one of the industrial partners to take full advantage of their Industrial Supervisors' expertise and the available instrumentation to complete the library-generation aspect of their research projects. All 6 ESRs will return to Birmingham for their final 2 months to allow their Academic Supervisors to oversee directly the final stages of their PhD thesis preparation.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-01-01"], "Project_ID": ["765116"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI VERONA"], "EU_Contribution": ["EUR 1 098 720"], "Project_Title": ["INnovative Verona university\u2019s Inter-disciplinary, Inter-sectoral and International Training Experience"], "Total_Cost": ["EUR 2 197 440"], "Country": ["Italy"], "Project_ACR": ["INVITE"], "Technology_Description": "INVITE is a doctoral programme at the University of Verona (UNIVR), Italy, with a strong inter-sectoral, inter-disciplinary and international research and training dimension. The project is co-financed by the Regione del Veneto and involves many partner organisations: 17 universities and research centres in Europe and beyond, 13 enterprises and organisations from the economic sector, 3 public organisations and 1 network. ", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2016 - Co-funding of regional, national and international programmes"], "Funding_scheme": ["MSCA-COFUND-DP - Doctoral programmes"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["754345"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2016"]}, -{"Partners": ["FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS", "RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN", "EML EUROPEAN MEDIA LABORATORY GMBH", "CEDAT 85 SRL"], "EU_Contribution": ["EUR 414 000"], "Project_Title": ["Hands-free Voice-enabled Interface to Web Applications for Smart Home Environments"], "Total_Cost": ["EUR 414 000"], "Country": ["Greece", "Germany", "Germany", "Italy"], "Project_ACR": ["LISTEN"], "Technology_Description": "Nowadays, it is becoming increasingly affordable to enhance the home environment with several automation schemes, allowing remote control of e.g., heating/cooling, communication, lighting, media, etc. Such smart home functionalities are essential for people with disabilities and the elderly, as they not only provide assistive control of important everyday functionalities, but may prove to be life-saving in case of emergency. However, smart home functionalities may become useless for people who need those most, if they cannot be accessed via a natural, easy to use, interface.", "To": ["2019-05-31, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Greece"], "Activity": ["Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-06-01"], "Project_ID": ["644283"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["UNIVERSITE DE RENNES I", "ELASTISYS AB", "TECHNISCHE UNIVERSITAET BERLIN", "U-HOPPER SRL"], "EU_Contribution": ["EUR 2 067 625,44"], "Project_Title": ["FogGuru: Training the Next Generation of European Fog Computing Experts"], "Total_Cost": ["EUR 2 067 625,44"], "Country": ["France", "Sweden", "Germany", "Italy"], "Project_ACR": ["FogGuru"], "Technology_Description": "\"A survey of 1000+ IT professionals has shown that the biggest challenge faced by the cloud computing industry today is the \"\"lack of [human] resources / expertise\"\". The objective of FogGuru is to train eight talented early-stage researchers with an innovative and intersectoral research program to constitute the next generation of European Cloud and Fog computing experts. Besides their scientific and technical education, FogGuru ESRs will receive extensive training in technological innovation and entrepreneurship as well as soft skills. These combined skills will enable them to fully master the innovation process stemming from fundamental research towards invention and development of innovative products and services, and to real-life deployment, experimentation and engagement with beta-testers.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-09-01"], "Project_ID": ["765452"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "UNIVERSITE CLERMONT AUVERGNE", "COMMUNAUTE D' UNIVERSITES ET ETABLISSEMENTS UNIVERSITE BOURGOGNE - FRANCHE - COMTE", "UNIVERSITA DEGLI STUDI DI UDINE", "UNIVERSIDADE DE COIMBRA", "UNIVERSITEIT GENT", "IMASENIC ADVANCED IMAGING S.L."], "EU_Contribution": ["EUR 2 266 907,76"], "Project_Title": ["AdvanCed Hardware/Software Components for Integrated/Embedded Vision SystEms"], "Total_Cost": ["EUR 2 266 907,76"], "Country": ["Spain", "France", "France", "Italy", "Portugal", "Belgium", "Spain"], "Project_ACR": ["ACHIEVE"], "Technology_Description": "ACHIEVE-ETN aims at training a new generation of scientists through a research programme on highly integrated hardware-software components for the implementation of ultra-efficient embedded vision systems as the basis for innovative distributed vision applications. They will develop core skills in multiple disciplines, from image sensor design to distributed vision algorithms, and at the same time they will share the multidisciplinary background that is necessary to understand complex problems in information-intensive vision-enabled applications. Concurrently, they will develop a set of transferable skills to promote their ability to cast their research results into new products and services, as well as to boost their career perspectives overall. Altogether, ACHIEVE-ETN will prepare highly skilled early-stage researchers able to create innovative solutions for emerging technology markets in Europe and worldwide but also to drive new businesses through engaging in related entrepreneurial activities. The consortium is composed of 6 academic and 1 industrial beneficiaries and 4 industrial partners. The training of the 9 ESR\u2019s will be achieved by the proper combination of excellent research, secondments with industry, specific courses on core and transferable skills, and academic-industrial workshops and networking events, all in compliance with the call\u2019s objectives of international, intersectoral and interdisciplinary mobility.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-10-01"], "Project_ID": ["765866"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 263 440,80"], "Project_Title": ["Understanding how plants overcome drought by controlling stomatal function: applicability and impacts on agriculture"], "Total_Cost": ["EUR 263 440,80"], "Country": ["Spain"], "Project_ACR": ["AgroPHYS"], "Technology_Description": "Land plants have coped with drought since they first colonized dry land. Drought is the most frequent cause of water stress \u2013 a functional and structural plant response to low water availability. An understanding of the impact, mechanisms and traits underlying drought tolerance in agricultural plant species is essential to improve productivity, and it further represents a major European priority (SFS-01-2016): optimizing agriculture in a changing climate with reduced water availability and a growing population. To address this urgent need it is necessary to first understand how stomata regulate leaf gas exchange, since stomatal is the main limitation of photosynthesis in crops under water stress. Both hydraulic and non-hydraulic or hormonal signals are the main drivers of stomatal regulation. Therefore, AgroPHYS proposes to investigate how these signals interact to protect plants against damaging desiccation. This project will generate physiological knowledge, at UTAS, from a range of experimental techniques and apply it to a physiology-based model and an automatic plant-based sensor to guide both irrigation management and research, at IRNAS-CSIC. The objectives of AgroPHYS are (i) to evaluate the relative importance and coordination of hydraulic and hormonal signals in plant stomatal responses to drought and recovery, and (ii) to apply this knowledge, by means of a mechanistic model and a plant sensor, to predict productivity relative to water consumption in agricultural plant species with different water use strategies. The outgoing research group is at the cutting-edge of physiological research and the environment of learning will provide maximum benefit to the candidate and excellent opportunities to interact with researchers from across the globe. These skills and knowledge will be transferred back to IRNAS-CSIC, providing essential data not only for scientific research on plant function but also for precision agriculture and optimal management of irrigation.", "To": ["2020-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-08-01"], "Project_ID": ["751918"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITEIT UTRECHT"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["Towards a mathematical conjecture for the Landau-Ginzburg/conformal field theory correspondence and beyond"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["MACOLAB"], "Technology_Description": "Initially a model to describe superconductivity, Landau-Ginzburg (LG) models were promoted in the late 80s to supersymmetric quantum field theories (QFTs) completely characterized by a polynomial W called potential. They gained importance in string theory and algebraic geometry as they play an interesting role in homological mirror symmetry. On the other hand, conformal field theories (CFTs) have been another kind of QFTs which display conformal symmetry. They have focused many efforts to understand the mathematical structures which encode them, e.g. inspiring the definition of vertex operator algebras (Borcherds, Fields medalist \u201988) or pushing forward our knowledge of modular tensor categories. Despite seeming two very different topics, LG models and CFTs are intimately related via a result of theoretical physics \u2014 the LG/CFT correspondence\u2014 stating that the infrared fixed point of a LG model with potential W is a CFT of central charge c(W). Mathematically this implies equivalences of categories of matrix factorizations (which describe defects of LG models) and categories of representations of vertex operator algebras (which describe defects of CFT). Up to date, we lack a complete understanding of the LG/CFT correspondence and we only have a few examples. The main goal of this Marie Curie is to find a mathematical statement for it, via completing a list of examples, exploring their properties (e.g. tensoriality or even modularity of the categories) and then attacking the main goal. Utrecht University (host institution) is one of the few places in Europe hosting experts in representation, category and Galois theory and mathematical physics, providing exactly the necessary and complementary expertise required to achieve this goal. These results will build a surprising bridge between very different areas of mathematics, opening new research gates completely inspired by physics.", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["747555"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FUNDACIO PRIVADA INSTITUT CATALA D'INVESTIGACIO QUIMICA", "FUNDACIO PRIVADA INSTITUT CATALA D'INVESTIGACIO QUIMICA"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Separation membranes for carbon dioxide removal from gas streams"], "Total_Cost": ["EUR 150 000"], "Country": ["Spain", "Spain"], "Project_ACR": ["MEMCARB"], "Technology_Description": "Carbon dioxide separation, capture and utilization is expected to become a major business opportunity in the near future. Beyond current industrial needs for natural gas or biogas purification, regulatory issues imposing emission control will also contribute to a fast growth in this market. At the industrial level, CO2 separation is still an expensive process, typically based in alkaline amine solutions or cryogenic distillation, and low-cost alternatives are needed. Membrane-based technologies are the most preferred for gas purification processes due to their easy implementation and very low operational costs. However, CO2 separation through membrane systems is not competitive nowadays, due to the low selectivity and poor stability of the available materials. This weakness precludes fully exploitation of the intrinsic benefits (functional and economic) of membrane technologies.", "To": ["2019-10-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-05-01"], "Project_ID": ["780255"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["KATHOLIEKE UNIVERSITEIT LEUVEN", "RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN", "UNIVERSITEIT GENT", "MONTANUNIVERSITAT LEOBEN", "UNIVERSITA DEGLI STUDI DI PADOVA", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "LINKOPINGS UNIVERSITET", "KUNGLIGA TEKNISKA HOEGSKOLAN", "SHANKS VALORIZATION & QUARRY", "ITALCEMENTI FABBRICHE RIUNITE CEMENTO SPA"], "EU_Contribution": ["EUR 3 844 721,16"], "Project_Title": ["EU Training Network for Resource Recovery through Enhanced Landfill Mining"], "Total_Cost": ["EUR 3 844 721,16"], "Country": ["Belgium", "Germany", "Belgium", "Austria", "Italy", "Switzerland", "Sweden", "Sweden", "Belgium", "Italy"], "Project_ACR": ["NEW-MINE"], "Technology_Description": "Europe has somewhere between 150,000 and 500,000 landfill sites, with an estimated 90% of them being \u201cnon-sanitary\u201d landfills, predating the EU Landfill Directive of 1999. These older landfills tend to be filled with municipal solid waste and often lack any environmental protection technology. In order to avoid future environmental and health problems, many of these landfills will soon require expensive remediation measures. This situation might appear bleak, but it does present us with an exciting opportunity for a combined resource-recovery and remediation strategy, which will drastically reduce future remediation costs, reclaim valuable land, while at the same time unlocking billions of tonnes of valuable resources contained within these landfills. However, the widespread adoption of Enhanced Landfill Mining (ELFM) in the EU, as envisaged by NEW-MINE, urgently requires skilled scientists, engineers, economists and policy makers who can develop cost-effective, environmentally friendly ELFM practices and regulatory frameworks. All this demands a European commitment to concerted, inter- and transdisciplinary research and innovation. The NEW-MINE project trains 15 early-stage researchers (ESRs) in all the aspects of landfill mining, in terms of both technological innovation and multi-criteria assessments for ELFM. The technological innovation follows a value-chain approach, from advanced landfill exploration, mechanical processing, plasma/solar/hybrid thermochemical conversion and upcycling, while the multi-criteria assessment methods allow the ESRs to compare combined resource-recovery/remediation ELFM methods with the \u201cDo-Nothing\u201d, \u201cClassic remediation\u201d and \u201cClassic landfill mining with (co-)incineration\u201d scenarios. By training the ESRs in scientific, technical and a range of soft skills, all based on a collaboration involving EU-leading institutes, they become highly sought-after scientists and engineers for the rapidly emerging ELFM and recycling industries.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-09-01"], "Project_ID": ["721185"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Dissection of the mammalian transcription termination mechanism by CRISPRi technology."], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["dCas9"], "Technology_Description": "RNA polymerase II (RNAPII) transcribes protein-coding genes in eukaryotes. The proper RNAPII transcription termination is crucial for generation of functional mRNAs, and then proteins. Termination, or stop of RNA synthesis, may occur before or after mRNA 3\u2019-end cleavage and polyadenylation. In the last decade many details have been acquired about mRNA maturation, but still little is known about the termination per se. In this proposal I will redress this problem.", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["747391"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF SOUTHAMPTON", "INSTITUT DE RECHERCHES EN INGENIERIE DES SURFACES SAS", "UNIVERSIDAD DE BURGOS", "INSTITUTO PEDRO NUNES ASSOCIACAO PARA A INOVACAO E DESENVOLVIMENTO EM CIENCIA E TECNOLOGIA", "JIHLAVAN, AS", "CESKE VYSOKE UCENI TECHNICKE V PRAZE", "JOHN CRANE UK LIMITED", "ARTIA NANO - ENGINEERING & CONSULTING IKE", "FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS"], "EU_Contribution": ["EUR 3 510 527,04"], "Project_Title": ["SOLUTION - Solid lubrication for emerging engineering applications"], "Total_Cost": ["EUR 3 510 527,04"], "Country": ["United Kingdom", "France", "Spain", "Portugal", "Czech Republic", "Czech Republic", "United Kingdom", "Greece", "Greece"], "Project_ACR": ["SOLUTION"], "Technology_Description": "SOLUTION will provide research and training program for 14 early stage researchers (ESR) pursuing their PhD in various disciplines covering the broadly defined area of solid lubricant coatings. The project combines theoretical approaches represented by advanced nanoscale simulations, laboratory design and fabrication of novel solid lubricants supported by simulations, and the up-scaling of promising solutions and their application in selected emerging engineering applications.", "To": ["2021-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Jiri Matas", "Tel.: +420 22435721", "Fax: +420 224357385", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555"], "From": ["2017-02-01"], "Project_ID": ["721642"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["RIJKSUNIVERSITEIT GRONINGEN", "UNIVERSITA DEGLI STUDI DI PAVIA", "SANKO TEKSTIL ISLETMELERI SANAYI VETICARET ANONIM SIRKETI", "RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN", "TECHNISCHE UNIVERSITAET GRAZ", "SESAM-BIOTECH GMBH", "NORGES MILJO-OG BIOVITENSKAPLIGE UNIVERSITET", "UNIVERSITY OF YORK", "DSM FOOD SPECIALTIES BV", "WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER"], "EU_Contribution": ["EUR 3 078 262,44"], "Project_Title": ["Harnessing the power of enzymatic oxygen activation"], "Total_Cost": ["EUR 3 078 262,44"], "Country": ["Netherlands", "Italy", "Turkey", "Germany", "Austria", "Germany", "Norway", "United Kingdom", "Netherlands", "Germany"], "Project_ACR": ["OXYTRAIN"], "Technology_Description": "For the selective and effective incorporation of oxygen into biological molecules (oxygenation reaction), several enzyme types have evolved in nature. They catalyse crucial reactions in various metabolic routes. The chemistry feasible with these biocatalysts is unrivalled when compared with conventional chemical methods. Therefore, these oxygenating enzymes are very promising tools in biotechnological approaches. However, when compared with other enzyme classes, such as hydrolases, oxygenases are still in their infancy considering their biotechnological potential. To fully exploit the catalytic power of oxygenases, several hurdles have to be taken for which a higher level of knowledge on these enzymes is needed while also technical aspects have to be solved.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["722390"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["DANMARKS TEKNISKE UNIVERSITET", "TECHNISCHE UNIVERSITEIT DELFT", "RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN", "SILICOLIFE LDA", "CHALMERS TEKNISKA HOEGSKOLA AB", "SESAM-BIOTECH GMBH", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE"], "EU_Contribution": ["EUR 3 994 075,80"], "Project_Title": ["Predictive and Accelerated Metabolic Engineering Network"], "Total_Cost": ["EUR 3 994 075,80"], "Country": ["Denmark", "Netherlands", "Germany", "Portugal", "Sweden", "Germany", "Switzerland"], "Project_ACR": ["PAcMEN"], "Technology_Description": "The world economy is dependent on fossil resources: oil, gas and coal. The fossil resources are finite and their consumption causes catastrophic environmental changes. Therefore we need to move towards sustainable economy using renewable resources for energy and chemicals production. Via metabolic engineering approach, novel microbial cells can be created that can convert biomass and waste into fuels and chemicals. Metabolic engineering however distinguishes itself from other engineering disciplines by low predictability of the design and long turnover times for the cell factory construction and screening. Therefore there is a need for scientists, who can address these challenges.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["722287"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "FORSCHUNGSZENTRUM JULICH GMBH", "HELMHOLTZ-ZENTRUM FUER UMWELTFORSCHUNG GMBH - UFZ", "UNIVERSITE DE LIEGE", "EBERHARD KARLS UNIVERSITAET TUEBINGEN", "KOBENHAVNS UNIVERSITET", "UNIVERSITE DE LAUSANNE", "UNIVERSITE DE NEUCHATEL", "MUQUANS", "ITASCA CONSULTANTS"], "EU_Contribution": ["EUR 3 865 769,64"], "Project_Title": ["European training Network for In situ imaGing of dynaMic processes in heterogeneous subsurfAce environments"], "Total_Cost": ["EUR 3 865 769,64"], "Country": ["France", "Spain", "Germany", "Germany", "Belgium", "Germany", "Denmark", "Switzerland", "Switzerland", "France", "France"], "Project_ACR": ["ENIGMA"], "Technology_Description": "The ENIGMA network will train a new generation of young researchers in the development of innovative sensors, field survey techniques and inverse modelling approaches. This will enhance our ability to understand and monitor dynamic subsurface processes that are key to the protection and sustainable use of water resources. ENIGMA focuses mainly on critical zone observation, but the anticipated technological developments and scientific findings will also contribute to monitor and model the environmental footprint of an increasing range of subsurface activities, including large-scale water abstraction and storage, enhanced geothermal systems and subsurface waste and carbon storage. While many subsurface structure imaging methods are now mature and broadly used in research and practice, our ability to resolve and monitor subsurface fluxes and processes, including solute transport, heat transfer and biochemical reactions, is much more limited. The shift from classical structure characterization to dynamic process imaging, driven by ENIGMA, will require the development of multi-scale hydrogeophysical methods with adequate sensitivity, spatial and temporal resolution, and novel inverse modelling concepts. For this, ENIGMA will gather (i) world-leading academic teams and emerging companies that develop innovative sensors and hydrogeophysical inversion methods, (ii) experts in subsurface process upscaling and modelling, and (iii) highly instrumented field infrastructures for in-situ experimentation and validation. ENIGMA will thus create a creative and entrepreneurial environment for trainees to develop integrated approaches to water management with interdisciplinary field-sensing methods and novel modelling techniques. ENIGMA will foster EU and international cooperation in the water area by creating new links between hydrogeological observatories, academic research groups, innovative industries and water managers for high-level scientific and professional training.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["722028"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["KUNGLIGA TEKNISKA HOEGSKOLAN", "KUNGLIGA TEKNISKA HOEGSKOLAN"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Dried Blood Spot sampling at home in Therapeutic Drug Monitoring"], "Total_Cost": ["EUR 150 000"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["xMEMSDBS"], "Technology_Description": "A new disposable sampling device that allows quantitative measurements from Dried Blood Spots (DBS) has been developed with support of the ERC AdG xMEMS.", "To": ["2018-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["727818"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["IBM RESEARCH GMBH"], "EU_Contribution": ["EUR 175 419,60"], "Project_Title": ["Monolithic Optoelectronic Devices on Silicon"], "Total_Cost": ["EUR 175 419,60"], "Country": ["Switzerland"], "Project_ACR": ["MODES"], "Technology_Description": "Nowadays, microelectronics set the pace for the whole knowledge-based economy and society in terms of the ever rising demand for mobile devices and the exponentially growing internet data transfer. However, the widening gap between the increasing number of transistors on a single Si chip and the delivered performance indicates the approaching limits of classical device scaling. Additionally, this miniaturization results in severe energy dissipation in the interconnection of devices. A smart way to overcome this emerging power consumption crisis is to avoid heating by replacing the on-chip and/or chip-to-chip electrical interconnects with optical interconnects. Due to their direct bandgap, III-V compounds are ideal for the integration of photonics with Si-based electronics on the very same chip. This would enable large-scale optoelectronics integration hindered so far by coupling- and overlay issues introduced by state-of-the-art III-V bonding on Silicon. ", "To": ["2018-06-30, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-07-01"], "Project_ID": ["704045"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Anderson Transition in a Quantum Gas Signatures and Characterization"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["AnTraQuGa"], "Technology_Description": "Anderson localization (AL) \u2013 an effect arising from interference of multiple-scattering events and leading to a complete halt of transport in disordered media \u2013 is a fundamental phenomenon, ubiquitous in all wave physics. ", "To": ["2017-12-31, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2016-01-01"], "Project_ID": ["655933"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["PERCUROS BV", "ACADEMISCH ZIEKENHUIS LEIDEN", "UNIVERSITAETSMEDIZIN GOETTINGEN - GEORG-AUGUST-UNIVERSITAET GOETTINGEN - STIFTUNG OEFFENTLICHEN RECHTS", "UNIVERSITEIT MAASTRICHT", "ITHERA MEDICAL GMBH", "TAGWORKS PHARMACEUTICALS BV", "RAYFOS LTD", "TECHNISCHE UNIVERSITAET MUENCHEN", "MAUNA KEA TECHNOLOGIES", "GAMMA TECHNOLOGIES LIMITED", "ANTIBODIES FOR RESEARCH APPLICATIONS BV", "TECOBIOSCIENCES GMBH", "ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 2 430 000"], "Project_Title": ["Preclinical Intra-Operative Image-Guided Surgery and Post-Operative Radiotherapy of Tumours"], "Total_Cost": ["EUR 2 430 000"], "Country": ["Netherlands", "Netherlands", "Germany", "Netherlands", "Germany", "Netherlands", "United Kingdom", "Germany", "France", "United Kingdom", "Netherlands", "Germany", "Netherlands", "Germany"], "Project_ACR": ["PRISAR"], "Technology_Description": "The main objective and basic concept of our proposal is to improve intra-operative and post-operative targeted surgical probes and new detection systems for surgical intervention of cancer. The work revolves around the mobility of clinicians, scientists and technologists between twelve consortium partners and across four different countries. The goal is the implementation of inter-disciplinary, inter-sector, cross-training of personnel. As a consequence, this will serve to accelerate the development of improved imaging technologies and hybrid fluorescence/radionuclide probes for the surgical intervention of cancer. The hypothesis is that if we can develop a hybrid probe for both targeted image-guided surgery and post-operative molecular radiotherapy, we would be implementing a revolutionary imaging and therapeutic approach for oncology surgeons to help their patients by improving better overall survival and quality of life for the patient. There are four key objectives within this project: 1) synthesis of a near infra-red fluorescence (NIRF)-dye conjugated to a peptide that is targeted towards a tumour associated antigen, 2) deliver a novel clinical optoacoustic handheld camera to detect the fluorescence probe in deep tissue, 3) validate the probe/target combination across the subcellular, cellular, endoscopic and macroscopic levels with state-of-art technologies, and 4) develop the probe further by targeting a radionuclide entity to the fluorescent construct for postoperative radiotherapy. Surgeons would have a more definitive reference for resection, if the tumour margin can be clearly defined. If this can be achieved, the impact would be (a) reduced recurrence rates in patients by lowering the risk of residual tumour tissue remaining after surgery and as a consequence improve survival, (b) minimised removal of healthy tissues, c) reduced patient morbidity and hospital stay and d) significant health cost benefits.", "To": ["2019-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Netherlands"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2015-02-01"], "Project_ID": ["644373"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["QUEEN MARY UNIVERSITY OF LONDON"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Role of GST gene variation in susceptibility to mercury (Hg)-induced neurodevelopmental disorders (NDD) in zebrafish"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["GSTHgNDD"], "Technology_Description": "Environmental factors, including the heavy metal mercury, are recognized as having a dominant influence on the aetiology and prevalence of neurodevelopmental behavioural disorders. This proposal will develop a new model for assessing the role of gene:environment interactions, specifically genetic predisposition for toxicity, in risk for disease, and identify early markers predictive of toxicity and later phenotypes. This will directly relate to the EC work program for Health, demographic change and wellbeing, with respect to both 'Personalized medicine' for non-communicable diseases and 'Early development' addressing mental health from childhood to older ages. The project uses the zebrafish model to investigate the relationship between glutathione-S-transferase (GST)-related genetic background, developmental exposure to mercury, and risk for neurodevelopmental disorders. This will be achieved by exposure of wild-type and CRISPR-generated Gst mutant embryos to mercury, and testing whether genetic predisposition leads to increased risk for toxin-induced behavioural phenotypes. We will test for altered biochemical, transcriptomic and epigenomic modifications that may serve as potential early markers for insult. The results obtained in this proposal will have significant impact on the ability to conduct individual and population specific toxicity risk assessment, and may lead to novel measures for early detection of increased risk and alleviation of potential adverse outcomes. The high-quality original research presented in the proposal will not only enable the Experienced Researcher to reach a position of professional maturity in her career, but will also allow her to develop a spectrum of new and interdisciplinary skills, integrating her previous training and knowledge into the behavioural genetics skills set. This project will also allow Dr. Brennan's group to integrate developmental toxicology into existing behavioural research, and will generate new collaborations.", "To": ["2019-06-19, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-20"], "Project_ID": ["705572"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "THE UNIVERSITY OF EXETER", "WAGENINGEN UNIVERSITY", "TECHNISCHE UNIVERSITAET DRESDEN", "KOBENHAVNS UNIVERSITET", "UNIVERSIDAD DE VALLADOLID", "UNIVERSITEIT UTRECHT", "FUNDACION CIDAUT", "FRIEDRICH-SCHILLER-UNIVERSITAT JENA", "UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK"], "EU_Contribution": ["EUR 3 896 688,10"], "Project_Title": ["Critical Transitions in Complex Systems"], "Total_Cost": ["EUR 3 896 688,10"], "Country": ["United Kingdom", "United Kingdom", "Netherlands", "Germany", "Denmark", "Spain", "Netherlands", "Spain", "Germany", "Ireland"], "Project_ACR": ["CRITICS"], "Technology_Description": "Complex systems research has been on the forefront of scientific priorities of many national research councils and the EU for more than a decade. Many very interesting phenomena have been identified and explored, but the development of the underpinning mathematical theory has been lagging behind. The proposed training network builds on an emerging development in applied mathematics to provide proper mathematical theory for the existence of early-warning signals for sudden changes in dynamical behaviour, so-called critical transitions, which have been reported by applied scientists in various contexts. Practical implications for the existence of such early-warning signals are far reaching, since these would enable the development of better control strategies to avoid or diminish the effect of catastrophes. Topical examples include epileptic seizures, stock market collapses, earthquakes, and climate. Attending to the mathematical underpinning for critical transitions in complex systems, it is apparent that the relevant mathematical discipline of bifurcation theory, that has been developed to great acclaim and use for primarily low-dimensional deterministic autonomous (i.e. intrinsically time-independent) dynamical systems, and (in the context of phase transitions) for material science, does not apply without nontrivial modification to most of the complex systems contexts. The training network is a response to the needs of applied scientists (including many in the private sector) for a proper mathematical underpinning of early-warning signals. After their training, the trained researchers will be at the very forefront of this rapidly developing field, with many practical skills and crucial theoretical insights into the possibilities (and impossibilities) of early-warning signals for critical transitions in a wide range of contexts.", "To": ["2019-03-31, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-04-01"], "Project_ID": ["643073"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Conserving the Legacy of Evolution into the Future"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["CLEF"], "Technology_Description": "Conserving the Legacy of Evolution (CLEF) would provide a comprehensive framework for translating biodiversity datasets into conservation plans. We now have a unique opportunity to improve the outlook for biodiversity by taking advantage of the wealth of newly available data on species ranges, functional characteristics, and phylogenetic data. CLEF proposes to: (1) develop sophisticated, yet easy-to-use biodiversity models that improve our understanding of where diversity occurs and better predict how diversity might change in the future, and (2) integrate the output of these biodiversity models with systematic conservation planning. CLEF would advance a new generation of biodiversity modelling that considers multiple species in one step rather than the standard practice of estimating species diversity by aggregating individual models. Early work has suggested these multi-species biodiversity models show great promise for improving present and future biodiversity estimates, but these models have yet to be comprehensively tested. Here, we will build and test these models for plant species in the French Alps, and compare the outputs to existing process-based models at identical scale and resolution. The second phase of CLEF is to develop a tool that directly uses the outputs of these models in conservation prioritization software. This tool will have the option of including phylogenetic, functional data, and future distributions by building on recent developments in this area. CLEF will demonstrate this approach for 2700 plant species to assign conservation priorities for the entire French Alps Region considering functional diversity, evolutionary diversity, climate and land-use change and protected area status. The methods resulting from CLEF could be used for any species-level biodiversity dataset\u2014helping scientists and conservationists better understand, predict, and plan to keep evolution\u2019s legacy intact.", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2015-09-01"], "Project_ID": ["659422"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UMWELTBUNDESAMT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (UBA GMBH)", "SUOMEN YMPARISTOKESKUS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "FORSCHUNGSZENTRUM JULICH GMBH", "HELMHOLTZ-ZENTRUM FUER UMWELTFORSCHUNG GMBH - UFZ", "THE RESEARCH COMMITTEE OF THE TECHNICAL UNIVERSITY OF CRETE", "CONSIGLIO NAZIONALE DELLE RICERCHE", "EUROPEJSKIE REGIONALNE CENTRUM EKOHYDROLOGII POLSKIEJ AKADEMII NAUK", "UNIVERZITET U NOVOM SADU", "SVERIGES LANTBRUKSUNIVERSITET", "NATURAL ENVIRONMENT RESEARCH COUNCIL", "VLAAMS GEWEST", "INSTITUT PO BIORAZNOOBRAZIE I EKOSISTEMNI IZSLEDVANIYA BALGARSKA AKADEMIYA NA NAUKITE", "GISAT S.R.O.", "HELSINGIN YLIOPISTO", "MASINOTEK OY", "SENCKENBERG GESELLSCHAFT FUR NATURFORSCHUNG", "GEOHIRES INTERNATIONAL GMBH", "MAGYAR TUDOMANYOS AKADEMIA OKOLOGIAI KUTATOKOZPONT", "BEN-GURION UNIVERSITY OF THE NEGEV", "LATVIJAS UNIVERSITATES AGENTURA LATVIJAS UNIVERSITATES BIOLOGIJAS INSTITUTS", "RIJKSUNIVERSITEIT GRONINGEN", "FUNDACAO DA FACULDADE DE CIENCIAS DA UNIVERSIDADE DE LISBOA FP", "UNIVERSITATEA DIN BUCURESTI", "INSTITUTE OF LANDSCAPE ECOLOGY OF THE SLOVAK ACADEMY OF SCIENCES", "ZNANSTVENORAZISKOVALNI CENTER SLOVENSKE AKADEMIJE ZNANOSTI IN UMETNOSTI", "UNIVERSIDAD DE GRANADA", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "BIOSENSE INSTITUTE - RESEARCH AND DEVELOPMENT INSTITUTE FOR INFORMATION TECHNOLOGIES IN BIOSYSTEMS"], "EU_Contribution": ["EUR 4 999 138"], "Project_Title": ["European Long-Term Ecosystem and socio-ecological Research Infrastructure"], "Total_Cost": ["EUR 4 999 138"], "Country": ["Austria", "Finland", "France", "Germany", "Germany", "Greece", "Italy", "Poland", "Serbia", "Sweden", "United Kingdom", "Belgium", "Bulgaria", "Czech Republic", "Finland", "Finland", "Germany", "Germany", "Hungary", "Israel", "Latvia", "Netherlands", "Portugal", "Romania", "Slovakia", "Slovenia", "Spain", "Spain", "Serbia"], "Project_ACR": ["eLTER"], "Technology_Description": "A collective effort is needed to create the environmental research infrastructure for answering pressing questions in a world of rapid social, economic and environmental change.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["INFRAIA-1-2014-2015 - Integrating and opening existing national and regional research infrastructures of European interest"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Austria"], "Activity": ["Other", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations"], "From": ["2015-06-01"], "Project_ID": ["654359"], "Call_for_Proposal": ["H2020-INFRAIA-2014-2015"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM", "UNIVERSITA CA' FOSCARI VENEZIA", "ASTON UNIVERSITY", "FONDAZIONE PER LA RICERCA E L'INNOVAZIONE", "UNIVERSIDAD DE GRANADA", "LUNDS UNIVERSITET", "UNIVERSITE DE MONTPELLIER", "HOCHSCHULE KARLSRUHE-TECHNIK UND WIRTSCHAFT", "UNIONE REGIONALE DELLE CAMERE DI COMMERCIO INDUSTRIA, ARTIGIANATO E AGRICOLTURA DEL VENETO", "CENTRE FOR EUROPEAN POLICY STUDIES", "STEINBEIS TRANSFERZENTREN GMBH AN DER HOCHSCHULE KARLSRUHE", "VERKET F\u00d6R INNOVATIONSSYSTEM", "GALDON SOFTWARE SA", "RIEKE PACKAGING SYSTEMS LIMITED", "BUREAU SATORI SAS", "UNIVERSITE DE NEUCHATEL", "NATIONAL UNIVERSITY OF SINGAPORE PUBLIC COMPANY LIMITED BY GUARANTEE", "CORNELL UNIVERSITY", "THE REGENTS OF THE UNIVERSITY OF CALIFORNIA", "UNIVERSITY OF SAN DIEGO"], "EU_Contribution": ["EUR 1 057 500"], "Project_Title": ["Smart Manufacturing for EU Growth and Prosperity"], "Total_Cost": ["EUR 1 057 500"], "Country": ["United Kingdom", "Italy", "United Kingdom", "Italy", "Spain", "Sweden", "France", "Germany", "Italy", "Belgium", "Germany", "Sweden", "Spain", "United Kingdom", "France", "Switzerland", "Singapore", "United States", "United States", "United States"], "Project_ACR": ["MAKERS"], "Technology_Description": "MAKERS will bring together leaders from business, academia and policy to study issues related to the drivers and dynamics of sustaining the competitiveness of EU manufacturing sectors. The project\u2019s innovative research, training and mobility activities will address key concerns related to the historic opportunity for the EU to lead a manufacturing renaissance that not only upgrades existing manufacturing competences but, more importantly, develops new technological capabilities across EU regions to support regional industrial resilience for more distributed and sustainable socio-economic growth and prosperity. ", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["691192"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM", "ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Towards solving myopia: from genes to pathways using an integrated approach"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["MYOP-PATH"], "Technology_Description": "Background: ", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["648268"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["UNIVERSITAT DE BARCELONA", "LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN", "UNIVERSITE DE NEUCHATEL", "THE UNIVERSITY OF STIRLING", "STOCKHOLMS UNIVERSITET", "THE UNIVERSITY OF EDINBURGH", "ECOLE NORMALE SUPERIEURE"], "EU_Contribution": ["EUR 3 670 853,76"], "Project_Title": ["Diaphora: Philosophical Problems, Resilience and Persistent Disagreement"], "Total_Cost": ["EUR 3 670 853,76"], "Country": ["Spain", "Germany", "Switzerland", "United Kingdom", "Sweden", "United Kingdom", "France"], "Project_ACR": ["DIAPHORA"], "Technology_Description": "DIAPHORA serves as a European research and training platform for collaborative research on the nature of philosophical problems, their resilience and the sources of persistent divergence of expert opinion about them, and their relation to conflicts in the practical sphere. More specifically, DIAPHORA\u2019s 3 principal research objectives are (A) to diagnose what makes philosophical problems so resilient and to clarify to what extent the sustained lack of convergence in philosophy can successfully be explained by the hardness of its problems; (B) to explain why the tendency has not been towards a general agnosticism about candidate solutions, but rather towards divergence, and to identify features of philosophical method that allow for such persistent peer disagreement; and (C) to explore whether the dynamics of philosophical debate, despite the subject\u2019s highly theoretical nature, bears important and instructive resemblances to the dynamics of debates about more practical matters and their political and socio-economical antecedents \u2013 and hence whether philosophical problems and their attempted resolution can illuminate, and be illuminated by, the procedural and methodological difficulties besetting strategies for the adjudication of public affairs, thereby determining what philosophical thought might contribute to society at large. DIAPHORA joins 7 leading European research centres in philosophy, and 5 partner organisations, 3 of which from the non-academic sector, in the fields of international conflict management, mediation and policy-making, as well as the analysis of social conflict and cultural diversity. It undertakes to provide 14 Early Stage Researchers with the knowledge and skills necessary to meet the demands of top-level research within its remit, as well as professional complementary skills training in both the academic and non-academic sectors, with the goal of widening their potential societal contributions and improving their individual career prospects.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["675415"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM", "ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM"], "EU_Contribution": ["EUR 1 495 715"], "Project_Title": ["Origins of Alzheimer's disease across the life-course"], "Total_Cost": ["EUR 1 495 715"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["ORACLE"], "Technology_Description": "The origins of Alzheimer\u2019s disease (AD) remain elusive. The long pre-clinical phase of AD is universally recognized, but it is not known when predisposition for AD develops nor when the first signs and symptoms become discernable. In this regard, an essential role is played by the \u2018reserve\u2019 capacity of the brain, which is built up in early life and acts as buffer against adverse risk factors later in life. However, life-time trajectories of build up and loss of reserve and its determinants remain poorly understood.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["678543"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM", "ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Cerebellar modules and the Ontogeny of Sensorimotor Integration"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["COSI"], "Technology_Description": "The perfect execution of a voluntary movement requires the appropriate integration of current bodily state, sensory input and desired outcome. To assure that this motor output becomes and remains appropriate, the brain needs to learn from the result of previous outputs. The cerebellum plays a central role in sensorimotor integration, yet -despite decades of studies- there is no generally excepted theory for cerebellar functioning. I recently demonstrated that cerebellar modules, identified based on anatomical connectivity and gene expression, differ distinctly in spike activity properties. It is my long-term goal to identify the ontogeny of anatomical and physiological differences between modules, and their functional consequences. My hypothesis is that these differences can explain existing controversies, and unify contradicting results into one central theory. ", "To": ["2021-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["680235"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM", "ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM"], "EU_Contribution": ["EUR 1 969 586,04"], "Project_Title": ["Embryonic origins of cardiovascular health in later life: disentangling early causal pathways in a lifecourse perspective"], "Total_Cost": ["EUR 1 969 586,04"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["EMBRYOandLATERHEALTH"], "Technology_Description": "Children born preterm or with a small size at birth have increased risks of cardiovascular disease and type 2 diabetes in adulthood. These intriguing associations strongly suggest that common diseases have at least part of their origins in early fetal life. From both an etiological and preventive perspective, it is important to disentangle the early fetal critical periods and causal pathways. An accumulating body of evidence suggests that early pregnancy, or even the preconception period, may influence the risk of cardiovascular and metabolic disease throughout the lifecourse. The main hypothesis for this project is that adverse exposures before or very early in pregnancy induce embryonic and placental developmental adaptations, which permanently affect cardiovascular and metabolic development and predispose individuals to both adverse outcomes at birth and cardiovascular and metabolic dysfunction and diseases in later life. I will use an integrated epidemiological, molecular and clinical full lifecourse approach from preconception to adulthood embedded in three population-based cohort studies. Innovative element are: 1) focus on developmental adaptations during the embryonic phase and early placentation assessed by advanced imaging studies at 6, 8, 10 and 12 weeks of gestation; (2) detailed cardiovascular and metabolic studies in infancy and late childhood, including 3T MRI of the heart, aorta, liver and abdomen, metabolomics analyses; and (3) genome-wide DNA-methylation studies to identify specific DNA-methylation changes related to preconception or early pregnancy exposures, which persist in late childhood and adulthood and are associated with cardiovascular and metabolic outcomes in later life. With these approaches, this project will provide unique and important new perspectives into the earliest origins of cardiovascular disease and type 2 diabetes and will ultimately contribute to development of preventive strategies focused on future parents and children.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["648916"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["AGENCIA PER A LA COMPETITIVITAT DE LA EMPRESA"], "EU_Contribution": ["EUR 5 097 600"], "Project_Title": ["ACCI\u00d3 programme to foster mobility of researchers with a focus in applied research and technology transfer"], "Total_Cost": ["EUR 10 195 200"], "Country": ["Spain"], "Project_ACR": ["TECNIOspring PLUS"], "Technology_Description": "TECNIOspring PLUS Fellowship Programme is proposed by ACCI\u00d3, the Catalan Agency for Business and Competitiveness, attached to the Ministry for Business and Labour of the Government of Catalonia. ", "To": ["2021-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2015-FP - Marie Sk\u0142odowska-Curie Co-funding of regional, national and international programmes (COFUND-FP)"], "Funding_scheme": ["MSCA-COFUND-FP - Fellowship programmes"], "Coordinated_in": ["Spain"], "Activity": ["Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2016-07-01"], "Project_ID": ["712949"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2015"]}, -{"Partners": ["UNIVERSITE DE BORDEAUX", "UNIVERSITE DE BORDEAUX"], "EU_Contribution": ["EUR 1 859 413"], "Project_Title": ["Unraveling the origin of the Initial Mass Function"], "Total_Cost": ["EUR 1 859 413"], "Country": ["France", "France"], "Project_ACR": ["COSMIC-DANCE"], "Technology_Description": "Despite the tremendous progress achieved over the past decade, the study of stellar formation is far from complete. We have not yet measured the minimum mass for star formation, nor the shape of the IMF down to the least massive free-floating planets, or know how universal this shape is. Although clusters are the building blocks of galaxies, little is known about their early dynamical evolution and dispersal into the field. The main culprit for this state of affairs is the high level of contamination and incompleteness in the sub-stellar regime, even for the best photometric and astrometric surveys.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["682903"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["THE HEBREW UNIVERSITY OF JERUSALEM"], "EU_Contribution": ["EUR 91 254,60"], "Project_Title": ["Smart Markets via Computation"], "Total_Cost": ["EUR 91 254,60"], "Country": ["Israel"], "Project_ACR": ["SMAC"], "Technology_Description": "E-commerce, modern-day government auctions, the sharing economy \u2013 these all have in common the optimization of resource allocation through the combination of economics and computation. This trend holds enormous socio-economic opportunity: for example, it allows online auctions, personalized advertising that supports the internet ecosystem, government repacking of radio spectrum to support growing communication needs, and flexible pricing that reflects true demand. It also poses an enormous challenge due to the sophisticated treatment of resources it requires, a challenge which theoretical computer science and algorithmic game theory in particular are uniquely positioned to address. ", "To": ["2017-09-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["708935"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM", "ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM"], "EU_Contribution": ["EUR 149 937"], "Project_Title": ["Automated framework for rapid simulations of high-detail brain models"], "Total_Cost": ["EUR 149 937"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["BrainFrame"], "Technology_Description": "Traditional methods of software modeling and simulation take prohibitive amounts of time to run for the size and complexity of biologically realistic neuron populations (e.g. >1 million). For instance, simulation of a 100 high-detail (Inferior-Olive) neuron-network for 10 minutes of brain time take 42 hours to complete on an modern PC workstation. To tackle this problem - common to the international neuroscience community -, we have turned to hardware-accelerated simulation platforms. We have employed award-winning, FPGA -based, dataflow machines provided by Maxeler Technologies, which offer high-performance computing capabilities and come with programming tools of unprecedented user friendliness. Our current Maxeler setups have offered impressive acceleration rates of more than 4 orders of magnitude (x10000). Despite the achieved speeds, however, we have found the Maxeler programming tools to be cumbersome to learn by neuromodelers with little hardware knowledge. Engineering personnel has, thus, been employed to assist them in (efficiently) translating and deploying their models. To streamline this process and bring a powerful tool directly to the hands of modelers, we propose BrainFrame, a novel system consisting of Maxeler hardware and a comprehensive software toolflow, effectively adding an abstraction level for neuromodelers to work on without specific knowledge of the underlying simulation platform. BrainFrame comprises a \u201cone-stop shop\u201d, integrated solution primarily targeting labs and companies active in the field of brain-modeling research and applications.", "To": ["2016-01-31, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2014 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-02-01"], "Project_ID": ["641000"], "Call_for_Proposal": ["ERC-2014-PoC"]}, -{"Partners": ["ISARDSAT SL", "UNIVERSITE PAUL SABATIER TOULOUSE III", "CENTRO DE ASESORIA DOCTOR FERRER SL", "INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT"], "EU_Contribution": ["EUR 895 500"], "Project_Title": ["Root zone soil moisture Estimates at the daily and agricultural parcel scales for Crop irrigation management and water use impact \u2013 a multi-sensor remote sensing approach"], "Total_Cost": ["EUR 895 500"], "Country": ["Spain", "France", "Spain", "France"], "Project_ACR": ["REC"], "Technology_Description": "Sustainable water use is a growing concern in Europe. Nowadays, agriculture is an important pressure on water resources especially in Mediterranean countries where irrigation can represent up to 80% of the consumptive uses of water. Increasing water use efficiency in agriculture has been thus identified as one of the key themes relating to water scarcity and drought (EEA Report No 1/2012). It now becomes necessary to improve on-farm irrigation management by adjusting irrigation to crop water requirements along the growing season.", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Spain"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations"], "From": ["2015-03-01"], "Project_ID": ["645642"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM", "ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["DNA rEpair impaired Mice with accElerated Neurodegeneration as Tool to Improve Alzheimer therapeutics"], "Total_Cost": ["EUR 150 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["Dementia"], "Technology_Description": "Alzheimer\u2019s disease (AD) affects worldwide ~50 million people. Preclinical research relies mainly on transgenic mouse models overexpressing mutant human proteins that are altered in <5% of AD cases (e.g. \u03b2-amyloid and tau), however, despite prominent protein aggregates, they fail to show the dramatic neurodegeneration and cognitive decline of patients, indicating that plaques and tangles may not be the only requirement for AD. Age is the most determining factor in AD, but is poorly represented in current AD models.", "To": ["2016-12-31, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2014 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-07-01"], "Project_ID": ["665335"], "Call_for_Proposal": ["ERC-2014-PoC"]}, -{"Partners": ["PLANETEK ITALIA SRL", "PLANETEK HELLAS ETAIREIA PERIORISMENIS EFTHYNIS YPIRESIES CHARTOGRAFISIS MESO DORYFOROU", "NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA", "TECHNOLOGIKO PANEPISTIMIO KYPROU", "University of the Aegean-Research Unit", "UNIVERSITA DEGLI STUDI DI BARI ALDO MORO", "TWT GMBH SCIENCE & INNOVATION", "I-SEA", "CLOUDSIGMA AG"], "EU_Contribution": ["EUR 1 584 000"], "Project_Title": ["Semantic EO Data Web Alert and Retrieval Framework"], "Total_Cost": ["EUR 1 584 000"], "Country": ["Italy", "Greece", "Greece", "Cyprus", "Greece", "Italy", "Germany", "France", "Switzerland"], "Project_ACR": ["SEO-DWARF"], "Technology_Description": "Technological advances in remote sensing have increased the availability of satellite images with different spatiotemporal and spectral characteristics.There is difficulty for retrieving the most appropriate data for each user's needs.One key challenge is to connect the quantitative information of the EO images with the qualitative (high-level user queries) and be able to mine these connections in big archives.An inherent question arises; how to retrieve EO images based on user semantically aware questions.Content based EO image retrieval techniques have been introduced for bridging the gap between low-level image features and high-level queries.The main constraint of the existing approaches is the generalization of the problem.The formulated ontologies are not focused on the constraints of EO images.The main objective of SEO-DWARF is to realize the content-based search of EO images on an application specific basis.The marine application domain and data from Sentinels 1,2,3, ENVISAT will be used.Queries such as \u201cCalculate the rate of increasing chlorophyll in the NATURA area\u201d will be answered by the SEO-DWARF, helping users to retrieve the appropriate EO images for their specific needs or alert them when a specific phenomenon occurs.The research contains the:a) ontology formalization for the specific research topics,b) determination of the semantic queries for the application domains,c) algorithm development for extracting metadata from the EO images,d) design of an architecture of the platform to perform the semantic image retrieval and storage and management of the extracted metadata.All four aspects will be integrated in an innovative and user-friendly web based platform enabling the users to retrieve images for marine applications or register for a semantic alert.A strong and experienced research team, of 4 academic and 5 industrial partners, coming from Greece(3), Italy(2), Germany(1), France(1), Cyprus(1) and Switzerland(1) constitute the project\u2019s consortium.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Italy"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-01-01"], "Project_ID": ["691071"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "PERCUROS BV", "THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN", "TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY", "CARDIFF UNIVERSITY", "UNIVERSITAIR MEDISCH CENTRUM UTRECHT", "AO-FORSCHUNGSINSTITUT DAVOS", "AARHUS UNIVERSITET", "PROCORE LTD", "UNIVERSITEIT MAASTRICHT"], "EU_Contribution": ["EUR 3 971 459,88"], "Project_Title": ["Targeting Cartilage Regeneration in joint and intervertebral disc diseases"], "Total_Cost": ["EUR 3 971 459,88"], "Country": ["Netherlands", "United Kingdom", "Netherlands", "United Kingdom", "Israel", "United Kingdom", "Netherlands", "Switzerland", "Denmark", "Israel", "Netherlands"], "Project_ACR": ["TargetCaRe"], "Technology_Description": "Mobility, important for well-being, is seriously impaired by chronic low back pain and osteoarthritis in many people due to degeneration of cartilaginous tissue of the intervertebral disc and joint. To develop a treatment for these diseases this ETN aims to combine expertise in novel highly advanced drug delivery carriers with dedicated targeting tools, state of the art imaging techniques and expertise in stem cell and joint biology by training 15 young scientists in 12 partner institutes located in 5 different countries.", "To": ["2019-02-28, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2015-03-01"], "Project_ID": ["642414"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["ECOLE D'ECONOMIE DE PARIS", "ECOLE D'ECONOMIE DE PARIS"], "EU_Contribution": ["EUR 1 598 307,50"], "Project_Title": ["The Economics of Ethnic Prejudice"], "Total_Cost": ["EUR 1 598 307,50"], "Country": ["France", "France"], "Project_ACR": ["Econ_Prejudice"], "Technology_Description": "Why do ethnic differences matter in some cases and not in others? What determines the strength of ethnic self-identification? This question is central to understanding the consequences of ethnic divisions for conflict and economic development and their policy implications but it was neglected by economic research until now. This project aims at filling this gap by endogenizing ethnic identity. We study how the salience of ethnic differences depends on economic and social context and policies of nation building. Our research program is organized around 3 pillars focusing on social, economic, and political determinants of ethnic tensions, respectively. The first pillar tests social psychology theories of ethnic identity using natural experiments, generated by forced mass movements of ethnic groups in Eastern Europe and from Eastern Europe to Central Asia as a result of WWII. The second pillar studies how market interactions between representatives of different ethnic groups and, in particular, ethnic occupational segregation affects ethnic tensions in the context of historical anti-Jewish violence following agro-climatic income shocks in the 19th and 20th century Eastern Europe. The third pillar focuses on the effects of political manipulation on ethnic conflict in the context of the historical experiment of nation building in Central Asia. It studies how political empowerment of a certain ethnic elite in a multi-ethnic traditional society coupled with a set of nation-building policies affects ethnic conflicts depending on the pre-existing ethnic mix and the distribution of political power among ethnic elites. This research will shed light on factors that make ethnic diversity important for conflict and economic development.", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-11-01"], "Project_ID": ["646662"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["Mapping the neuronal representation in dorsal inferior colliculus through optical imaging, stimulus optimization and optogenetics"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["OPTIMAPIC"], "Technology_Description": "Despite being the most accessible subcortical auditory structure, little is known about the dorsal cortex (ICd) of the inferior colliculus. Limited physiological evidence hints at functions regarding detection of frequency-modulation, novel sounds and selective attention. This project tries to address three fundamental questions regarding the ICd, namely: (1) what are optimal stimuli for the neurons in the ICd, (2) why is the neuronal activity in ICd important for the organism and (3) how does the neuronal circuit achieve the necessary computation. Taking advantage of state-of-the-art in vivo optical imaging, I will search for effective stimulus features through a population-wide stimulus optimization approach (WP1). The ability to measure neuronal activity over weeks expands the range of sound stimuli researchers can deliver, providing a basis for a more unbiased stimulus search. Moreover, groups of cells that respond to similar features can be detected, while extra efforts can be diverted towards identifying optimal stimuli for the remaining cells. Secondly, a behavioural paradigm will be developed to probe the effect of selective attention on neuronal activity of the ICd (WP2). At the same time, comparing neuronal and behavioural response will help us understand how neuronal representations translate into percept and actions of the animal. Finally, I will investigate how neuronal activities in the ICd are shaped by projections from other brain regions, through the imaging of synaptic terminals from these inputs and, subsequently, optogenetic manipulations. The results will lead to a major understanding in the sensory processing at the auditory midbrain and the functional significance of its interactions with other brain regions. These research outcomes are not ends in themselves, but will provide the Fellow with a basis for further research as an independent group leader.", "To": ["2017-02-28, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-03-01"], "Project_ID": ["660157"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DELL'AQUILA", "UNIVERSITY OF NEWCASTLE UPON TYNE", "THE UNIVERSITY OF MANCHESTER", "ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM", "REGION HOVEDSTADEN"], "EU_Contribution": ["EUR 607 500"], "Project_Title": ["Training network for Research on molecUlar and Biomechanical Interactions in CONnective tissue disorders"], "Total_Cost": ["EUR 877 500"], "Country": ["Italy", "United Kingdom", "United Kingdom", "Netherlands", "Denmark"], "Project_ACR": ["RUBICON"], "Technology_Description": "RUBICON will establish a global network for staff exchange of scientists and for research training focussed on connective tissue disorders. It will bring together leading scientific groups from 5 European and 5 non-European countries who will study the molecular and biomechanical factors involved in the pathophysiology of connective tissues, including tendons, cartilage and bone. The ambitious objectives of RUBICON are to increase our knowledge of the mechanisms underlying diverse connective tissue disorders, identify commonalities and targetable pathways, and reinforce multidisciplinary awareness in this fundamental research field. ", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-01-01"], "Project_ID": ["690850"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["EUROPEAN VACCINE INITIATIVE - EEIG", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.", "Statens Serum Institut", "SCLAVO VACCINE ASSOCIATION", "ACADEMISCH ZIEKENHUIS LEIDEN", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "STICHTING WAGENINGEN RESEARCH", "ECRIN EUROPEAN CLINICAL RESEARCH INFRASTRUCTURE NETWORK", "EATRIS ERIC", "VACCINE FORMULATION INSTITUTE LIMITED", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "INSTITUTO DE BIOLOGIA EXPERIMENTAL E TECNOLOGICA", "GENIBET - BIOPHARMACEUTICALS SA", "HELMHOLTZ-ZENTRUM FUER INFEKTIONSFORSCHUNG GMBH", "Foundation BIOMEDICAL PRIMATE RESEARCH CENTRE", "LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE", "Department of Health", "MINISTERIE VAN VOLKSGEZONDHEID, WELZIJN EN SPORT", "INSTITUT DE RECERCA I TECNOLOGIA AGROALIMENTARIES", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "UNIVERSITE DE LAUSANNE", "UNIVERSITA' DEGLI STUDI DI SIENA", "UNIVERSITEIT LEIDEN", "INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE", "INSTRUCT ACADEMIC SERVICES LIMITED", "BIOASTER FONDATION DE COOPERATION SCIENTIFIQUE"], "EU_Contribution": ["EUR 10 599 993"], "Project_Title": ["European Vaccine Research and Development Infrastructure"], "Total_Cost": ["EUR 10 599 993"], "Country": ["Germany", "Germany", "Denmark", "Italy", "Netherlands", "France", "Netherlands", "France", "Netherlands", "United Kingdom", "United Kingdom", "Portugal", "Portugal", "Germany", "Netherlands", "United Kingdom", "United Kingdom", "Netherlands", "Spain", "Switzerland", "Switzerland", "Italy", "Netherlands", "France", "United Kingdom", "France"], "Project_ACR": ["TRANSVAC2"], "Technology_Description": "TRANSVAC2 is the follow-up project to its successful predecessor project TRANSVAC, the European Network of Vaccine Research and Development funded under FP7. The TRANSVAC2 consortium comprises a comprehensive collection of leading European institutions that propose to further advance with the previous initiative towards the establishment of a fully operational and sustainable European vaccine R&D infrastructure. TRANSVAC2 will support innovation for both prophylactic and therapeutic vaccine development based on a disease-overarching and one-health approach, thereby optimising the knowledge and expertise gained during the development of both human and animal vaccines. This will be achieved by bridging the translational gap in biomedical research, and by supporting cooperation between public vaccine R&D institutions of excellence, related initiatives and networks in Europe, and industrial partners. TRANSVAC2 will complement and integrate with existing European research infrastructures in both the public and private sectors. TRANSVAC2 will function as leverage and innovation catalyst between all stakeholders involved in vaccine R&D in Europe and -by providing integrated and overarching vaccine R&D services- will contribute to the development of effective products to address European and global health challenges, to controlling the burden and spread of infectious diseases, and reinforce the economic assets represented by vaccine developers in Europe.", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["INFRAIA-01-2016-2017 - Integrating Activities for Advanced Communities"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Other", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Other", "Research Organisations"], "From": ["2017-05-01"], "Project_ID": ["730964"], "Call_for_Proposal": ["H2020-INFRAIA-2016-1"]}, -{"Partners": ["STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["Parton Dynamics in QCD Hadron Structure: collinear FFs and unpolarized TMDs"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["ParDHonS_FFs.TMDs"], "Technology_Description": "This project is about the understanding of the structure and dynamics of hadrons in terms of their partonic constituents, quarks and gluons. The aim of this project is to achieve a state-of-the-art determination of collinear fragmentation functions (FFs) of charged pions and kaons, and of unpolarized transverse-momentum-dependent parton distribution functions (TMDs) of the proton. Cutting-edge statistical and computational tools, previously developed for a determination of collinear parton distribution functions (PDFs), will be generalized and used in conjunction with all the experimental information currently available. The results obtained on the one hand will provide precision tools for phenomenological studies in hadron-particle and high-energy collider physics, and on the other hand will improve the knowledge of nucleon structure and hadronization.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Research Organisations"], "From": ["2018-09-01"], "Project_ID": ["752748"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM", "POLITECNICO DI MILANO", "UNIVERSIDADE DO PORTO", "TECHNISCHE UNIVERSITEIT DELFT", "KUNGLIGA TEKNISKA HOEGSKOLAN", "TTY-SAATIO", "NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU", "UNIVERSITAT POLITECNICA DE VALENCIA", "VYSOKE UCENI TECHNICKE V BRNE", "MER MEC FRANCE", "ROADSCANNERS OY", "EVOLEO TECHNOLOGIES LDA"], "EU_Contribution": ["EUR 1 057 500"], "Project_Title": ["Rail Infrastructure Systems Engineering Network"], "Total_Cost": ["EUR 1 170 000"], "Country": ["United Kingdom", "Italy", "Portugal", "Netherlands", "Sweden", "Finland", "Norway", "Spain", "Czech Republic", "France", "Finland", "Portugal"], "Project_ACR": ["RISEN"], "Technology_Description": "Social and economic growth, security and sustainability in Europe are at risk of being compromised due to aging and failing railway infrastructure systems. This partly reflects a recognised skill shortage in railway infrastructure engineering. This project, RISEN, aims to enhance knowledge creation and transfer using both international and intersectoral secondment mechanisms among European Advanced Rail Research Universities/SMEs and Non-EU, world-class rail universities including the University of Illinois at Urbana Champaign (USA), Massachusetts Institute of Technology (USA), Southwest Jiaotong University (China) and University of Wollongong (Australia). This project adds research skill mobility and innovation dimension to existing bilateral collaborations between universities through research exchange, joint research supervision, summer courses, international training and workshops, and joint development of innovative inventions. It spans over 4 years from April 2016 to March 2020. ", "To": ["2020-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-04-01"], "Project_ID": ["691135"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["THE UNIVERSITY OF SHEFFIELD", "ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA", "FIN-CERAMICA FAENZA SPA", "BUDAI EGESZSEGKOZPONT KFT", "ANSYS FRANCE SAS", "ADAGOS", "AESCULAP AG"], "EU_Contribution": ["EUR 1 588 449,60"], "Project_Title": ["SPINe: Numerical and Experimental Repair strategies"], "Total_Cost": ["EUR 1 588 449,60"], "Country": ["United Kingdom", "Italy", "Italy", "Hungary", "France", "France", "Germany"], "Project_ACR": ["SPINNER"], "Technology_Description": "The SPINNER EID will train a group of Bioengineering early stage researchers to be in a position to design the next generation of repair materials and techniques for spine surgery. SPINNER brings together partners from the biomaterials (Finceramica), implantable devices (Aesculap), and computational modelling (Ansys, Adagos) industries with orthopaedic clinicians (National Centre for Spinal Disorders, NCSD) and academic experts in cell, tissue and organ scale biomaterials and medical device testing (Universities of Sheffield and Bologna). All projects will be fully grounded in practical industrial and clinical requirements, where the number of patients requiring complex spine surgery is rapidly expanding, and the biomedical engineering industry needs suitably trained, innovators to produce economic solutions to support healthy ageing for the people of Europe.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-01-01"], "Project_ID": ["766012"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["TECHNISCHE UNIVERSITEIT EINDHOVEN", "ABB SCHWEIZ AG"], "EU_Contribution": ["EUR 510 748,56"], "Project_Title": ["Advanced Solid State Transformers"], "Total_Cost": ["EUR 510 748,56"], "Country": ["Netherlands", "Switzerland"], "Project_ACR": ["ASSTRA"], "Technology_Description": "ASSTRA is an interdisciplinary training and research project that targets the development of advanced solid state transformer technology which enables a sustainable and flexible (\u2018Smart\u2019), DC-equipped energy supply system with a large share of renewable energy sources. This futuristic electrification network has in its core a flexible power conversion unit, distributing electrical energy from sources to loads in a similar fashion as today\u2019s internet hubs distribute information from senders to receivers. Specifically, this power conversion unit integrates state-of-the-art technology, such as Silicon-Carbide, in order to implement power electronics building blocks and magnetic components featuring breaking through performances, which will ultimately enable its industrial deployment. ", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-01-01"], "Project_ID": ["765774"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["CENTRE TECNOLOGIC DE TELECOMUNICACIONS DE CATALUNYA", "ALCATEL-LUCENT DEUTSCHLAND AG"], "EU_Contribution": ["EUR 495 745,92"], "Project_Title": ["Future Optical Networks for Innovation, Research and Experimentation"], "Total_Cost": ["EUR 495 745,92"], "Country": ["Spain", "Germany"], "Project_ACR": ["ONFIRE"], "Technology_Description": "Future (5G) services will impose stringent requirements in the design and operation of transport networks: increased capacity, low latency, high availability and dynamicity, reduced service provisioning with lower OpEx, while considering end-to-end service objectives (QoS and QoT). ", "To": ["2021-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-10-01"], "Project_ID": ["765275"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Atomistic Electrodynamics-Quantum Mechanical Framework for Characterizing, Manipulating and Optimizing Nonlinear Optical Processes in 2D Materials"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ELECTROQUANTUM-2D"], "Technology_Description": "Two-dimensional (2D) materials, which include graphene, phosphorene, and transition metal dichalcogenides monolayers, exhibit extraordinary linear and nonlinear optical properties not attainable in bulk media. They find tremendous potentials in many photonic and optoelectronic applications, such as all-optical signal processing, optical amplification, nonlinear switching, optical microscopy, quantum detection, and sensing. The availability of first-principle, fast, efficient computer codes is a prerequisite to the bottom-up design of 2D materials. However, theoretical modeling of 2D materials faces great challenges as it needs to incorporate effects of finite size, edge truncation, periodic modulation, nonlocal, and quantum confinement. Here, we aim at developing atomistic electrodynamics-quantum mechanical theoretical models and implementing them in high-performance computing (HPC) software for characterizing, manipulating, and optimizing nonlinear optical processes (NOP) in 2D materials. The main objectives of this ambitious project are: (1) To develop a macroscopic electrodynamics approach for simulating NOP in 2D materials. (2) To develop an atomistic electrodynamics quantum mechanical framework for modeling NOP in 2D materials and compare the atomistic model to the macroscopic approach. (3) To develop user-friendly and reliable HPC software that seamlessly integrates and implements the theoretical models. (4) Using the software and theoretical models, emerging applications of 2D materials will be investigated, including solar cells, nonlinear microscopy, and biosensing. The project will have high impacts on: (1) advances in the science, technology, and industry of UK and Europe; (2) applicant\u2019s future career development; (3) research, industrial, and transferrable knowledge exchange between the host and applicant; (4) design and commercialization of 2D material enabled devices; (5) training of students and researchers in several interdisciplinary disciplines.", "To": ["2020-01-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-15"], "Project_ID": ["752898"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["VA-Q-TEC AG"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Thermally efficient, cost-reduced nanostructured foams for vacuum insulation panels"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["THEcore"], "Technology_Description": "Climate change is an energy problem, says the conclusion of studies related to global warming. Aware of this \u201cinconvenient truth\u201d, Europe launched strategies, with precise energy savings and gas emissions reductions, to be reached by 2020 and an ultimate sustainable energy system by 2050. As a large share of energy consumption is spent by the household sector (heating, air conditioning, refrigeration), advanced thermal insulation products give a crucial contribution to better energy efficiency.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-SE - Society and Enterprise panel"], "Coordinated_in": ["Germany"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-06-01"], "Project_ID": ["748256"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["POLITECHNIKA WARSZAWSKA", "INSTITUT JOZEF STEFAN", "POLITECHNIKA WROCLAWSKA", "SLOVENSKA TISKOVNA AGENCIJA DOO"], "EU_Contribution": ["EUR 1 273 500"], "Project_Title": ["Reverse EngiNeering of sOcial Information pRocessing"], "Total_Cost": ["EUR 1 314 000"], "Country": ["Poland", "Slovenia", "Poland", "Slovenia"], "Project_ACR": ["RENOIR"], "Technology_Description": "In today's world, access to information is a decisive factor advancing industry, society and even culture. It is therefore of great importance to understand why and how some information (e.g. some memes) spreads virally with great ease, while other is met with disinterest and omission. Uncovering the reasons may allow promoting important information, like warnings about cyber-attacks, while stifle harmful rumors, such as vaccines causing autism. The aim of the project is to treat the vast complexity of such information dynamics in social systems by involving researchers in social sciences, journalism, computing, data mining and complexity science.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Poland"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-01-01"], "Project_ID": ["691152"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["UNIVERSITA CA' FOSCARI VENEZIA"], "EU_Contribution": ["EUR 180 277,20"], "Project_Title": ["Reader, Author, Scholar in a Context of Information Overflow.How to master and manage knowledge when there is too much to know?"], "Total_Cost": ["EUR 180 277,20"], "Country": ["Italy"], "Project_ACR": ["RASCIO"], "Technology_Description": "The Mamluk period (1250-1517) is an example in terms of intellectual vivacity. Scholars and books travel easily, ideas are extensively discussed and shared, and the sum of knowledge available is always increasing. When it is no longer possible to master all the knowledge alone, and by heart, how do scholars compose new books?", "To": ["2020-01-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-15"], "Project_ID": ["749180"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["Biomechanical Characterization of Carotid Plaque Rupture"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["BIO-CAPTURE"], "Technology_Description": "Stroke is the second leading cause of mortality worldwide. Most stroke events are triggered by an atherosclerotic plaque rupture in a carotid artery. Current clinical decisions for the carotid plaque removal surgery are made without assessing the plaque rupture risk as no reliable means exists today. Biomechanics can help to develop such risk assessment tools; yet, the fundamental knowledge on biomechanical descriptors of plaque rupture is missing.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["749283"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["INTERNATIONALES INSTITUT FUER ANGEWANDTE SYSTEMANALYSE", "INTERNATIONALES INSTITUT FUER ANGEWANDTE SYSTEMANALYSE"], "EU_Contribution": ["EUR 1 819 250"], "Project_Title": ["The Demography of Sustainable Human Wellbeing"], "Total_Cost": ["EUR 1 819 250"], "Country": ["Austria", "Austria"], "Project_ACR": ["EmpoweredLifeYears"], "Technology_Description": "This project will apply two distinctly demographic concepts to research questions that go far beyond demography. The wellbeing indicators proposed here will be based on life table methods and the recently operationalized concept of Demographic Metabolism \u2013 modelling social change through the replacement of generations \u2013 will be used to get a quantitative analytical handle on the temporal dynamics of improving human wellbeing. ", "To": ["2022-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Austria"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-11-01"], "Project_ID": ["741105"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["HELSINGIN YLIOPISTO", "HELSINGIN YLIOPISTO"], "EU_Contribution": ["EUR 2 500 000"], "Project_Title": ["Age at maturity in Atlantic salmon: molecular and ecological dissection of an adaptive trait"], "Total_Cost": ["EUR 2 500 000"], "Country": ["Finland", "Finland"], "Project_ACR": ["MATURATION"], "Technology_Description": "Life history is the nexus of biology, because various biological questions ultimately revolve around the causes and consequences of variation in reproduction and survival, i.e. fitness. Traditionally, a major tool in life-history research has been quantitative genetics because it provides an important statistical link between phenotype and genotype. However, the mechanisms by which evolution occurs may remain unclear unless such traditional approaches are combined with molecular investigations. Another complicating factor is that the fitness of male vs female life histories do not always align, and hence life history traits may be shaped by sexual conflict. This is why life-history approaches focusing on both quantifying the conflict and understanding its resolution at the genetic level are needed. ", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["742312"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "ALBERT-LUDWIGS-UNIVERSITAET FREIBURG", "UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA", "TECHNISCHE UNIVERSITAET WIEN", "UNIVERZA V MARIBORU", "KARLSRUHER INSTITUT FUER TECHNOLOGIE"], "EU_Contribution": ["EUR 2 012 205,24"], "Project_Title": ["Towards Next-generation Eco-efficient PHOTO and EMULSION PolymerisationsImparting Synergy to Process, Products and Applications"], "Total_Cost": ["EUR 2 012 205,24"], "Country": ["France", "Germany", "Germany", "Spain", "Austria", "Slovenia", "Germany"], "Project_ACR": ["PHOTO-EMULSION"], "Technology_Description": "The polymer industry is going through one of the most significant periods of change in its history. Driven by new environmental regulations, the development of eco-efficient processes and zero-VOC products has become an absolute necessity. In this field, 2 technologies stand out: Polymerisation in dispersed media and Photopolymerisation. To maintain EU leadership in this sector, PHOTO-EMULSION aims at training a creative, entrepreneurial & innovative next-generation of 8 Early-Stage Researchers (ESRs) who can push towards new eco-friendly polymerisation processes. Our primary strength is a demanding technical knowledge base bringing together, for the first time, all disciplines related to these 2 strategic fields. Secondly, we will broaden traditional doctoral training by targeting transferable and specialized skills sought after by the employers, and learned through innovative methods: tandem ESRs, distance language learning, ESR as itinerant science educator, online courses, ESR-led subproject, highly interactive meetings, and industrial secondments. In research, we will develop a \u201chybrid\u201d next-generation technology based on thiol-ene photopolymerisation in dispersed media. Advanced manufacturing based on photoreactor promises a wave of high sulfur content dispersed products (films, nanoparticles, porous network). Their outstanding properties open the door to applications responding to current Industral needs such as non-leaching materials, O2 barrier and biobased waterborne coatings, biologically-active particles, hybrid nanosensors and monolithic chromatography column. PHOTO-EMULSION involves a high-quality research network including 8 internationally reputed academic institutions, 4 leading companies and 2 non-profit organisations. Balanced & EU-wide, our diversity expresses through the participation of 8 countries (Austria, France, Germany, Ireland, Poland, Slovenia, Sweden & Spain), 50% female scientists-in-charge, and structures supporting gender equality.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["765341"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Boosting Reward-based Attention through VEstibular STimulation"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["BRAVEST"], "Technology_Description": "Intrinsically rewarding stimuli strongly favour attentional capture (AC) in humans, this effect being dramatic in a number of addiction disorders. The physiology of this phenomenon is poorly understood, but recent neuroimaging studies point to a role of the Anterior Cingulate Cortex (aCC) in this kind of attentional engagement. A way to act on this circuitry would provide compelling evidence and be a major advance for the cognitive and clinical neuroscience of motivation. ", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2018-02-01"], "Project_ID": ["746154"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["OXFORD BROOKES UNIVERSITY"], "EU_Contribution": ["EUR 255 349,80"], "Project_Title": ["Social Sustainability and Urban Regeneration Governance: An International Perspective"], "Total_Cost": ["EUR 255 349,80"], "Country": ["United Kingdom"], "Project_ACR": ["SURGE"], "Technology_Description": "The aim of the research is to support the career development of an experienced researcher through an interdisciplinary project that tackles a crucial policy issue for cities globally, that of urban regeneration governance. Developing a novel interdisciplinary conceptual framework, and applying a stakeholder evaluative frame in the analysis, the project explores the governance of urban regeneration projects in two world cities, Vancouver and London.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["749154"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["HELSINGIN YLIOPISTO", "INTEGRATED CARBON OBSERVATION SYSTEM EUROPEAN RESEARCH INFRASTRUCTURE CONSORTIUM", "PIN SOC.CONS. A R.L. - SERVIZI DIDATTICI E SCIENTIFICI PER L UNIVERSITA DI FIRENZE", "EUROPEAN SOCIAL SURVEY EUROPEAN RESEARCH INFRASTRUCTURE CONSORTIUM", "CESSDA AS", "ECRIN EUROPEAN CLINICAL RESEARCH INFRASTRUCTURE NETWORK", "STICHTING ASTRON, NETHERLANDS INSTITUTE FOR RADIO ASTRONOMY", "INSTITUT MAX VON LAUE - PAUL LANGEVIN", "STICHTING EGI", "AGENZIA PER LA PROMOZIONE DELLA RICERCA EUROPEA", "TURUN YLIOPISTO"], "EU_Contribution": ["EUR 1 999 867,50"], "Project_Title": ["European Research Infrastructures in the International Landscape"], "Total_Cost": ["EUR 1 999 867,50"], "Country": ["Finland", "Finland", "Italy", "United Kingdom", "Norway", "France", "Netherlands", "France", "Netherlands", "Italy", "Finland"], "Project_ACR": ["RISCAPE"], "Technology_Description": "RISCAPE will provide systematic, focused, high quality, comprehensive, consistent and peer-reviewed international landscape analysis report on the position and complementarities of the major European research infrastructures in the international research infrastructure landscape. ", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["INFRASUPP-01-2016 - Policy and international cooperation measures for research infrastructures"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments", "Other", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Research Organisations", "Research Organisations", "Other", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["730974"], "Call_for_Proposal": ["H2020-INFRASUPP-2016-1"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI BRESCIA", "UNIVERSITA DEGLI STUDI DI BRESCIA"], "EU_Contribution": ["EUR 2 084 180,82"], "Project_Title": ["Spatiotemporal multimode complex optical systems"], "Total_Cost": ["EUR 2 084 180,82"], "Country": ["Italy", "Italy"], "Project_ACR": ["STEMS"], "Technology_Description": "The STEMS project is about exploiting the new concept that has been recently introduced by the PI and his co-workers, namely the self-control of the spatial coherence of optical beams in multimode nonlinear optical fibers. This concept will enable a breakthrough technology, capable of delivering high-energy optical pulses with high-average powers and much higher beam quality from fiber lasers than what is possible today. High-power fiber lasers are largely limited by transverse mode instabilities, and the loss of spatial coherence in delivery fibers. Optical fibers provide the backbone of today\u2019s internet communication networks, and enable compact, low cost light sources for a variety of industrial and biomedical applications. In most of these applications, single-mode fibers are used. Replacing single-mode fibers with multimode fibers leads to a dramatic growth of transmission capacity, and a substantial increase of average power and pulse energy from fiber lasers. However, because of spatial dispersion and resulting mode interference, multimode fibers suffer from an inherent randomization of the spatial transverse beam profile, leading to a loss of spatial coherence. My approach is to exploit the intensity dependent refractive index, or Kerr nonlinearity, of glass fibers to recover the spatial coherence of a multimode wave, and compensate for temporal modal dispersion.", "To": ["2022-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["740355"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITE DE NEUCHATEL", "UNIVERSITE DE NEUCHATEL"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Ultrastable optical frequency comb systems"], "Total_Cost": ["EUR 150 000"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["ULTRASTABLE"], "Technology_Description": "The invention of optical frequency combs revolutionized numerous fields in metrology and was honoured by the 2005 Nobel Prize in Physics. Frequency combs have many new emerging applications in optical telecommunications, broadband high-precision spectroscopy and sensing, etc. Monitoring of environmentally relevant gases and pollutants, medical sensing of biomarkers in human breath, or remote sensing of gases relevant for resources exploitation or farming are important areas, in which frequency comb systems might find large applications in the future. However, so far, frequency comb systems are mainly used in basic research, despite their large potential for commercial applications. New technology solutions are required to enlarge the application range of this technology and make it accessible for real-world systems.", "To": ["2018-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["727493"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM", "SILIXA LTD", "RS HYDRO LTD", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "NATURALEA CONSERVACIO, SL", "LUXEMBOURG INSTITUTE OF SCIENCE AND TECHNOLOGY", "SVERIGES LANTBRUKSUNIVERSITET", "FORSCHUNGSVERBUND BERLIN EV", "HELMHOLTZ ZENTRUM POTSDAM DEUTSCHESGEOFORSCHUNGSZENTRUM GFZ", "HYDRORESEARCH SAM JOHANSSON AB", "UVDYNE LIMITED", "ISARDSAT SL", "EVVOS SA", "SETUR - INGENIERIE - AUDIT - CONSEIL"], "EU_Contribution": ["EUR 2 115 000"], "Project_Title": ["Smart high-frequency environmental sensor networks for quantifying nonlinear hydrological process dynamics across spatial scales"], "Total_Cost": ["EUR 2 335 500"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom", "France", "Spain", "Spain", "Luxembourg", "Sweden", "Germany", "Germany", "Sweden", "United Kingdom", "Spain", "Luxembourg", "France"], "Project_ACR": ["HiFreq"], "Technology_Description": "Regulators and industries are challenged by the difficulty to analyse and predict the impact of nonlinear environmental processes on short-term and long-term responses of ecosystems to environmental change. Until very recently, the development of most conventional monitoring, forecasting and prediction tools has been based on the assumption of stationary environmental systems. In the context of global change these tools are increasingly pushed towards and even beyond their design limits (the latter resulting in the first line from the prevailing limitations in spatial and temporal resolution of environmental observations).", "To": ["2020-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-12-01"], "Project_ID": ["734317"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE", "STICHTING WAGENINGEN RESEARCH", "FRIEDRICH LOEFFLER INSTITUT - BUNDESFORSCHUNGSINSTITUT FUER TIERGESUNDHEIT", "THE PIRBRIGHT INSTITUTE LBG", "THE SECRETARY OF STATE FOR ENVIRONMENT, FOOD AND RURAL AFFAIRS", "MOREDUN RESEARCH INSTITUTE", "INSTITUTO NACIONAL DE INVESTIGACIONY TECHNOLOGIA AGRARIA Y ALIMENTARIA OA MP", "INSTITUT DE RECERCA I TECNOLOGIA AGROALIMENTARIES", "EIDGENOESSISCHES DEPARTEMENT DES INNERN", "PANSTWOWY INSTYTUT WETERYNARYJNY - PANSTWOWY INSTYTUT BADAWCZY", "MARINE SCOTLAND", "AARHUS UNIVERSITET", "AGENCE NATIONALE DE SECURITE SANITAIRE DE L'ALIMENTATION, DE L'ENVIRONNEMENT ET DU TRAVAIL", "THE UNIVERSITY OF EDINBURGH", "ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM", "ISTITUTO ZOOPROFILATTICO SPERIMENTALE DELLE VENEZIE", "THE UNIVERSITY OF NOTTINGHAM", "UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN", "International Livestock Research Institute", "COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION", "FEDERAZIONE EUROPEA DI ZOOTECNICA", "InSCREENeX GmbH", "Leica Microsystems CMS GmbH", "NOLDUS INFORMATION TECHNOLOGY BV", "EPIBIOSAFE LTD", "VERTEBRATE ANTIBODIES LIMITED", "INMUNOLOGIA Y GENETICA APLICADA SA", "INRA TRANSFERT S.A."], "EU_Contribution": ["EUR 9 999 140,50"], "Project_Title": ["Veterinary Biocontained facility Network for excellence in animal infectiology research and experimentation"], "Total_Cost": ["EUR 10 017 890,50"], "Country": ["France", "Netherlands", "Germany", "United Kingdom", "United Kingdom", "United Kingdom", "Spain", "Spain", "Switzerland", "Poland", "United Kingdom", "Denmark", "France", "United Kingdom", "Netherlands", "Italy", "United Kingdom", "Ireland", "Kenya", "Australia", "Italy", "Germany", "Germany", "Netherlands", "United Kingdom", "United Kingdom", "Spain", "France"], "Project_ACR": ["VetBioNet"], "Technology_Description": "VetBioNet seeks to complement and strengthen the present European capacity and competence to meet the challenges of (re)emerging infectious diseases by establishing a comprehensive network of pre-eminent European BSL3 infrastructures, international organisations, and industry partners that is dedicated to advance research on epizootic and zoonotic diseases and to promote technological developments. ", "To": ["2022-02-28, ongoing project"], "Meta": [""], "Topic_s": ["INFRAIA-01-2016-2017 - Integrating Activities for Advanced Communities"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Research Organisations", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-03-01"], "Project_ID": ["731014"], "Call_for_Proposal": ["H2020-INFRAIA-2016-1"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 200 194,80"], "Project_Title": ["Genomic and proteomic analysis of Palaeolithic, Neolithic and Bronze Age humans from Central-Southern Italy"], "Total_Cost": ["EUR 200 194,80"], "Country": ["Denmark"], "Project_ACR": ["PALAEO-ENEO"], "Technology_Description": "This project aims at reconstructing the ancestry and oral disease of Palaeolithic, Neolithic and Bronze Age anatomically modern humans from Central-Southern Italy, using genome-wide profiling and mass spectrometry-based proteomic analysis of skeletal remains and mineralised dental plaque (archaeological dental calculus). In Europe, the transition from hunter-gatherer to agricultural communities (Neolithisation) and the Bronze Age migration into Central Europe from the Asian steppe were the most important demographic events since the initial peopling by anatomically modern humans. However, until now, no Palaeolithic and only a few of Neolithic and Bronze age individuals from South Europe have been characterised for genomic analysis. As a consequence, the genetic base of outstanding peopling and migratory processes in prehistoric Europe, such as: (a) the East-West population structure among European hunter-gatherers, and (b) the Neolithic Southern European horizon known as the Cardial culture, still need to be fully understood. Similarly, metagenomic analysis of Palaeolithic and Neolithic dental calculus has been limited to preliminary screening of a limited number of samples, with no associated metaproteomic analysis. What taxonomic groups and metabolic functions were lost or gained with Neolithisation? How this affected oral heath? The genomic characterisation of Palaeolithic, Neolithic and Bronze Age humans from Southern Europe will be integrated with a metagenomic and metaproteomic analysis of dental calculus to produce the richest possible personal \u201c-omics\u201d profiling so far achievable for ancient humans. The two main research objectives are: 1. Integrate Palaeolithic, Neolithic and Bronze Age human genomic data from Central-Southern Italy within the genomic landscape available for all ancient and present-day West Eurasians, and 2. Reconstruct the oral microbiome, and its metabolic interactions with the host, before and after Neolithisation.", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["751349"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF GLASGOW", "UNIVERSITY OF NEWCASTLE UPON TYNE", "THE QUEEN'S UNIVERSITY OF BELFAST", "TURUN YLIOPISTO", "ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM", "MOSAIQUES DIAGNOSTICS GMBH", "IDRYMA IATROVIOLOGIKON EREUNON AKADEMIAS ATHINON", "TAMPEREEN YLIOPISTO", "GenomeScan B.V.", "ALMAC DIAGNOSTICS LIMITED"], "EU_Contribution": ["EUR 2 629 315,80"], "Project_Title": ["Translational Research Network in Prostate Cancer"], "Total_Cost": ["EUR 2 629 315,80"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom", "Finland", "Netherlands", "Germany", "Greece", "Finland", "Netherlands", "United Kingdom"], "Project_ACR": ["TransPot"], "Technology_Description": "The Translational Research Network for Prostate Cancer (TransPot) program adopts an innovative, multidisciplinary approach, providing highly sought-after, effective solutions for incurable prostate cancer (PC).", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["721746"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["CENTRO DE NEUROCIENCIAS E BIOLOGIACELULAR ASSOCIACAO", "FYZIOLOGICKY USTAV AKADEMIE VED CESKE REPUBLIKY VEREJNA VYZKUMNA INSTITUCE (VVI)", "UNIVERSITA DEGLI STUDI DI BARI ALDO MORO", "Faculdade de Farm\u00e1cia da Universidade de Lisboa", "INSTYTUT BIOLOGII DOSWIADCZALNEJ IM. M. NENCKIEGO POLSKIEJ AKADEMII NAUK", "UNIVERSIDADE DO PORTO", "INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE", "CONSIGLIO NAZIONALE DELLE RICERCHE", "HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 3 202 195,68"], "Project_Title": ["Bioenergetic Remodeling in the Pathophysiology and Treatment of Non-Alcoholic Fatty Liver Disease"], "Total_Cost": ["EUR 3 202 195,68"], "Country": ["Portugal", "Czech Republic", "Italy", "Portugal", "Poland", "Portugal", "France", "Italy", "Germany", "Spain"], "Project_ACR": ["Foie Gras"], "Technology_Description": "FOIE GRAS provides innovative training for 13 early stage researchers (ESRs) to answer two critical and unanswered questions: a) Is hepatic bioenergetic remodelling involved in NAFLD pathogenesis, and target for stratification or therapeutic/lifestyle interventions? and b) Is the disruption of the gut-liver axis involved in NAFLD progression? In Western Societies, there has been a recent surge of non-alcoholic fatty liver disease (NAFLD). Its progression to nonalcoholic steatohepatitis (NASH) is a leading risk factor for development of Type 2 diabetes, cirrhosis, and hepatocellular carcinoma. FOIE GRAS is first in supporting a cohesive and synergistic intersection of complementary and interdisciplinary training skills from academic and non-academic partners. FOIE GRAS combines strong scientific expertise with integrated and complementary training in translational research, clinical practice, technology commercialization, and public outreach, the combination of which in targeting NAFLD is lacking in the EU. Industrial partners CETICS, Mediagnost and Seahorse Biosciences provide experience on technology commercialization alongside scientific contributions while the affiliated patient organization will contribute with important training in societal awareness topics. ESRs training will utilize network-wide workshops and secondments to foster translation of basic research to clinical applications and SME creation. This diverse yet integrated skill set enhances the employment prospects of the trained researchers in both academic and non-academic sectors. Researchers will be endowed with excellent basic scientific knowledge and timely technology transfer know-how for developing novel therapeutic approaches for reversing the burden of NAFLD, thereby advancing both health and economic well-being of European citizens and approaching NAFLD research in the EU from its counterparts in the US and Asia.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Portugal"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations"], "From": ["2017-01-01"], "Project_ID": ["722619"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["THE UNIVERSITY OF SHEFFIELD", "FUNDACION PARA LA INVESTIGACION BIOMEDICA DEL HOSPITAL UNIVERSITARIO CLINICO SAN CARLOS", "HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH", "UNIVERSITE DE NANTES", "QUEEN MARY UNIVERSITY OF LONDON", "ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOCIENCIAS", "UNIVERSITAIR MEDISCH CENTRUM UTRECHT", "UNIVERSIDADE DA BEIRA INTERIOR", "SEQOMICS BIOTECHNOLOGIA KORLATOLT FELELOSSEGU TARSASAG", "INTELLIGENT PHARMA SL"], "EU_Contribution": ["EUR 3 818 970,36"], "Project_Title": ["Tribbles Research and Innovation Network"], "Total_Cost": ["EUR 3 818 970,36"], "Country": ["United Kingdom", "Spain", "Germany", "France", "United Kingdom", "Spain", "Netherlands", "Portugal", "Hungary", "Spain"], "Project_ACR": ["TRAIN"], "Technology_Description": "This proposal was developed in the context of the medical need to tackle the clinical consequences of obesity-related diseases more holistically. Dysregulation of common molecular pathways that govern the physiological functioning of adipocytes, immune cells and prostate epithelium cells have been reported in immuno-metabolic disease (such as obesity) and several cancers. The individual projects described in the proposal will investigate regulators of these pathways with a focus on a recently described family of pseudokinases, namely tribbles proteins, which have a key role in controlling immunity, metabolism and cancer, and which here will serve as prototypical examples for integrative metabolocentric cancer research. Tribbles are envisaged to contribute directly to the development and progression of prostate cancer, the prognosis of which is substantially worsened in individuals with immuno-metabolic disease.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-09-01"], "Project_ID": ["721532"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 200 194,80"], "Project_Title": ["Monotonicity in Logic and Complexity"], "Total_Cost": ["EUR 200 194,80"], "Country": ["Denmark"], "Project_ACR": ["MiLC"], "Technology_Description": "MiLC will develop logical characterisations of monotone complexity classes, yielding languages and systems which are machine-independent and well suited for reasoning over such classes of functions. Monotone Boolean functions abound in the theory of computation, e.g. in sorting algorithms and clique detection in graphs, and nonuniform classes of monotone functions have been well studied in computational complexity under the lens of monotone circuits. ", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["753431"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 200 194,80"], "Project_Title": ["Effects of common European tree species on interactions between C and N processes in soil and soil biota"], "Total_Cost": ["EUR 200 194,80"], "Country": ["Denmark"], "Project_ACR": ["AFOREST"], "Technology_Description": "One of the greatest challenges of the 21st century is to mitigate global climate changes caused by increasing emissions of greenhouse gases. Since soils constitute a larger carbon (C) pool than the vegetation and atmosphere together an important strategy could be to sequester more C in soils. Plant-soil interactions play an important role for ecosystem services such as C sequestration and N retention in soil and such interactions receive increasing attention among scientists and policymakers. Novel techniques such as next generation sequencing methods in combination with analysis of C stock patterns under different tree species present an opportunity to highlight complex processes and mechanisms which underlie C and N fluxes in soil. The proposed research is designed to (1) explore litter-mediated effects of common European tree species on C and N turnover in soil, (2) characterize effects of tree species on community structure and composition of soil biota, (3) evaluate the impact of common European tree species on metabolic diversity and structure and composition of functional genes related to C and N turnover: and finally, (4) to synthesize the role of soil biota for C and N turnover in soils. The research will be carried out within a unique common garden experiment with monoculture stands of six common European tree species; the broadleaves beech (Fagus sylvatica L.), pedunculate oak (Quercus robur L.), lime (Tilia cordata L.), sycamore maple (Acer pseudoplatanus L.) and ash (Fraxinus excelsior L.) and the conifer Norway spruce (Picea abies (L.) Karst.). The proposed Marie-Curie fellowship is promising to highlight impacts of common European trees on complex interactions among soil microbiota and soil fauna and highlights their role for C and N stocks and fluxes. Results obtained from this research will contribute to bridge gaps in ecological theory in term of ecosystem functions and services.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["747824"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KATHOLIEKE UNIVERSITEIT LEUVEN"], "EU_Contribution": ["EUR 160 800"], "Project_Title": ["Coping with Inhospitable Sweetness: Insights from a (Diversity)^3 Study of Nectar Acinetobacters"], "Total_Cost": ["EUR 160 800"], "Country": ["Belgium"], "Project_ACR": ["D3NAs"], "Technology_Description": "\"Plants are hotspots of microbial diversity, and novel lineages of plant-associated microorganisms are continuously described. Recently, floral nectar has been identified as the natural habitat of different highly adapted yeasts and bacteria which can withstand elevated sugar contents and the presence of plant secondary metabolites with defensive functions. As a consequence of their metabolism, these microorganisms can reduce the nutritional value of nectar and profoundly alter its chemistry, and thus modify pollinators\u2019 foraging behavior and indirectly affect plant fitness. Although the bacterial species Acinetobacter nectaris and A. boissieri (\"\"nectar acinetobacters\"\", NAs) are among the most frequent bacterial nectar-dwellers, their diversity and intriguing ubiquitous occurrence in floral nectar still remain poorly characterized. Through a comprehensive study of the phenotypic, phylogenetic and genomic diversity (\u201cdiversity(D)^3 approach\u201d) of NAs, the proposed project aims to explain why A. nectaris and A. boissieri are particularly well suited to thrive in the \u201cinhospitable sweetness\u201d of floral nectar. This research question will be addressed by using state-of-the-art methodologies of high-throughput phenotyping, phylogenetic inference and whole-genome sequencing and analysis. The combination of expertises in applied phylogenetics of the applicant (experienced researcher, ER) and in phenomics and genomics of the host institute will be key for a successful completion of the work plan. Additionally, the implementation of this action will involve training in management, communication, dissemination and exploitation of results, and networking, all of which will boost the ER's potential for reaching a position of professional maturity.\"", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["742964"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CONSIGLIO NAZIONALE DELLE RICERCHE"], "EU_Contribution": ["EUR 180 277,20"], "Project_Title": ["Photosynthetic energy balance, chloroplast integrity, carbon flow and epigenetic regulation of isoprenoid biosynthesis during leaf development and senescence"], "Total_Cost": ["EUR 180 277,20"], "Country": ["Italy"], "Project_ACR": ["LEAF-OF-LIFE"], "Technology_Description": "The methyl erythritol phosphate (MEP) pathway in the chloroplast synthesizes isoprenoids (a class of hydrocarbons) by almost exclusively utilising carbon and energy supplied by photosynthesis in plant leaves. Volatile isoprenoids (antioxidant hydrocarbons), isoprenoid-type cytokinins (plant \u2018youth\u2019 hormone), carotenoids (photoprotective pigments), and abscisic acid (plant \u2018stress\u2019 hormone) are some of the active isoprenoid end-products of the MEP pathway that play a role in leaf senescence. We aim to quantify and model age-specific relationships between photosynthesis and MEP pathway during natural and abiotic-stress induced leaf senescence in three different plant systems: wheat (a crop), poplar (a plantation tree) and Arabidopsis (the model species for genomics). By combining leaf age-specific chloroplast energy balance estimation through photosynthesis modelling, quantification of carbon demands of isoprenoid biosynthesis using stable isotope tracing and advanced real-time analytical techniques, monitoring plastome and chloroplast integrity, and whole-epigenome sequencing, LEAF-OF-LIFE will (i) develop a versatile quantitative method for predicting leaf senescence trajectories based on the relationship between photosynthesis and isoprenoid biosynthesis during senescence and (ii) identify novel gene cascades involved in epigenomic regulation of the MEP pathway during natural and abiotic stress-induced leaf senescence. A thorough understanding of leaf age-specific changes in energy and carbon demands of isoprenoid biosynthesis will provide a strong mechanistic basis to phenology models of autumn senescence in deciduous trees. Discovery of novel gene regulatory cascades involved in age-specific changes in isoprenoid biosynthesis will be spearheading new research intended to target MEP pathway so as to alter leaf life span (delay stress-induced leaf senescence) in major global crops and plantations.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations"], "From": ["2017-06-01"], "Project_ID": ["746821"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 200 194,80"], "Project_Title": ["Paleoproteomics for cultural heritage conservation: biomolecular analysis of ancient Egyptian paint binders"], "Total_Cost": ["EUR 200 194,80"], "Country": ["Denmark"], "Project_ACR": ["EGYPTOMICS"], "Technology_Description": "This project aims to identify the biological species of origin, as well as molecular damage, of proteins used as binding media in ancient Egypt painted artifacts and architecture specimens dating 3000 BC - 600 AD by applying mass spectrometry-based proteomic strategies.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["750270"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KAROLINSKA INSTITUTET"], "EU_Contribution": ["EUR 185 857,20"], "Project_Title": ["Molecular Mechanisms of Dynamic and Spatial Control of Eph Receptors clustering"], "Total_Cost": ["EUR 185 857,20"], "Country": ["Sweden"], "Project_ACR": ["DynaSpaCER"], "Technology_Description": "There is mounting evidence that the spatial and temporal organization of ligands at cell-cell interfaces modulates signaling. In particular, for Eph receptors and their ligands (ephrins) this phenomenon is widely recognized but poorly understood due to difficulties in controlling and analyzing membrane protein microenvironments at the nanoscale. A combination of different techniques ranging from DNA nanotechnology to high resolution microscopies via standard biochemical techniques and computational tools will be used to provide a molecular understanding of the roles of the spatial and temporal organization of ligands in receptor signaling. Substrates that recreate the intramembrane signalling geometry at cell-cell contacts are designed and produced by employing ligand decorated DNA nanostructures anchored on artificial supported lipid bilayers. This allows an unparalleled control of spatial distribution of the ligands and their dynamics. TIRF/STORM super-resolution microscopy is used to measure size and dynamics of clustering and biochemical assays will quantify the receptor spatial distribution and activation levels. Together with computational simulation and modeling of clustering dynamics, these efforts will lead to a molecular mechanism of spatial organization of ligands and receptors during clustering and how this affects signaling.", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["707203"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE FRANCIS CRICK INSTITUTE LIMITED"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Role of perforin-like proteins and phospholipases in malaria parasite egress"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["MalariaEgress"], "Technology_Description": "The malaria parasite Plasmodium falciparum, which causes ~600,000 deaths annually, propagates within host erythrocytes. Roughly synchronous egress of blood stage parasites in vivo causes the periodic fevers associated with malaria and is essential for parasite replication. Blocking parasite egress can stop disease progression, so understanding its mechanism is key to identifying new drug targets. Egress of malaria parasites from host erythrocytes involves the rupture of two membranes- the parasitophorous vacuole membrane and the erythrocyte membrane. It is unclear how the parasitophorous vacuole membrane ruptures during egress, and what mechanism is responsible for poration of the erythrocyte membrane. While it has been shown that egress is protease-dependent, the effector molecules that bring about the disruption of both membranes remain unknown. Potential effector molecules include parasite perforin-like proteins (PLPs) and phospholipases. This project aims to test the hypothesis that Plasmodium PLPs and phospholipases are involved in malarial egress. First, we will apply newly developed conditional knockout strategies to establish the role in egress of a candidate perforin-like protein. Second, we aim to devise a novel conditional genetic screen to identify egress related phospholipases in a medium-throughput manner. This work will add to the efforts being made to understand egress and will attempt to develop a much needed forward genetic screen in the malaria parasite. The interdisciplinary approach proposed here combines the experienced researcher (ER)\u2019s skills in genomics and the host laboratory\u2019s expertise in malarial cell biology and conditional knockout technologies. This will equip the ER with the right exposure and new skills to pursue a future independent research career in malaria research.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["751865"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KAROLINSKA INSTITUTET"], "EU_Contribution": ["EUR 185 857,20"], "Project_Title": ["An innovative class of nanoparticles (\u201cSmartCubes\u201d) for the targeted delivery of protein therapeutics"], "Total_Cost": ["EUR 185 857,20"], "Country": ["Sweden"], "Project_ACR": ["SmartCubes"], "Technology_Description": "'SmartCubes' are an innovative class of nanoparticles for the targeted delivery of protein therapeutics. The objective is to deliver high levels of membrane proteins to cancer cells to combat disease. I will achieve this by creating novel 'sponge-like' targeted nanoparticles (SmartCubes) to selectively deliver unprecedented levels of a cancer therapeutic protein to colon adenocarcinoma cells.", "To": ["2018-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["703666"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN", "STICHTING VU", "VRIJE UNIVERSITEIT BRUSSEL", "UNIVERSITETET I BERGEN", "ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOMATERIALES- CIC biomaGUNE", "WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER", "IMANOVA LIMITED", "ASTRAZENECA AB", "STICHTING VUMC"], "EU_Contribution": ["EUR 3 912 634,77"], "Project_Title": ["PET Imaging in Drug Design and Development"], "Total_Cost": ["EUR 3 912 634,77"], "Country": ["United Kingdom", "Netherlands", "Belgium", "Norway", "Spain", "Germany", "United Kingdom", "Sweden", "Netherlands"], "Project_ACR": ["PET3D"], "Technology_Description": "The drug development strategy currently pursued by the pharmaceutical industry worldwide is inefficient and unsustainable for the health care system. To keep the latter affordable, drug development should become more efficient and drug treatment should become more \u201cpersonalized\u201d and \u201crationalized\u201d. Molecular imaging can play a pivotal role in changing the landscape of drug design/development and improving the health care system. Positron Emission Tomography (PET) imaging, in particular, is the technology that has the potential to lead this fundamental innovation by providing at a much earlier stage reliable answers to key questions emerging during the care cycle: what and where is the disease? Is the disease accurately targeted by the therapy? Is the treatment effective? By answering the questions above, PET imaging has the capacity to render much more effectively the transition from pre-clinical to clinical phase, and to strongly facilitate the development of better drugs at an earlier stage and in a much more sustainable manner. The main obstacle to this change of paradigm in drug design and development is the lack of suitably trained translational scientists directly involved in PET imaging and imaging scientists with high-profile training in chemistry and PET-radiochemistry, which is particularly dramatic in Europe. This consortium is ideally suited to fill this gap, by providing top-quality training to the next generation of translational PET imaging scientists who will play a key role in shaping the future of drug design and development. The PET3D ETN will focus on 15 cutting-edge research projects in the 3 main therapeutic areas (oncology, cardiovascular, central nervous system) that will be conducted by 15 ESRs at 8 European beneficiary Institutions, 6 academic (all having a PET center on site) and 2 non-academic (one with a PET center on site and one big pharmaceutical company) representing the drug design and development terminus of the project.", "To": ["2020-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["675417"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["CARDIFF UNIVERSITY"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Artificial engineered Phonons for application in Integrated Photonics"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["APIP"], "Technology_Description": "Stimulated Brillouin (SBS) and Raman Scattering (SRS) effects have led to numerous applications in fiber optics (e.g. tunable laser and amplifiers). In integrated photonics, recent progress in opto-mechanics have shown that artificial analogue to the Raman effect, namely mechanical structure resonances, can be engineered and could results in new applications. That said, a few challenges must still be addressed before fiber applications of SRS can be transposed in a \u00b5m size optical chip. In particular the frequency of the mechanical resonances -aka artificial phonons- is still too low (<10Ghz) for most applications, and the light-phonon interaction is much weaker in waveguides compared to what is obtained in cavity opto-mechanics. Moreover current approaches relying on Radio-frequency measurements do not allow investigating high frequency (>10GHz) resonances. ", "To": ["2019-09-05, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-06"], "Project_ID": ["751939"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["GLAXOSMITHKLINE VACCINES SRL", "INSTITUTO DE MEDICINA MOLECULAR", "UNIVERSITA DEGLI STUDI DI MILANO", "UNIVERSITEIT LEIDEN", "ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOCIENCIAS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "THE UNIVERSITY OF MANCHESTER", "SVEUCILISTE U RIJECI, MEDICINSKI FAKULTET", "LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "GLYCOUNIVERSE GMBH & CO KGAA"], "EU_Contribution": ["EUR 3 554 499,69"], "Project_Title": ["A training network for the rational design of the next generation of well-defined glycoconjugate vaccines"], "Total_Cost": ["EUR 3 554 499,69"], "Country": ["Italy", "Portugal", "Italy", "Netherlands", "Spain", "France", "United Kingdom", "Croatia", "Germany", "Germany", "Germany"], "Project_ACR": ["GLYCOVAX"], "Technology_Description": "GLYCOVAX is a network for the education of promising young scientists who will learn how to rationally design a next generation of well-defined and innovative glycoconjugate vaccines to improve current preventive therapies and to tackle unmet medical needs. Glycoconjugate vaccines represent the key for success of vaccination in children. The covalent linkage to proteins renders carbohydrates able to evoke a T-cell memory response. Current vaccines are prepared from heterogeneous mixtures of sugars linked by unspecific methods to the carrier protein giving complex mixtures of products. Due to this intricate structure, it has not been possible to apply a medicinal chemistry approach in the development of glycoconjugate vaccines and to fully understand their mechanism of action. Combination of novel approaches for glycan synthesis and site-selective conjugation methods now gives access to conjugates defined in sugar component and attachment site, thus leading to robust structure-immunogenicity relationship. Advancements in structural biophysics can be applied to select the optimal glycan antigen. By combining the beneficiaries\u2019 expertise in carbohydrate synthesis, bioconjugation, high throughput screening, structural glycobiology, vaccinology and immunology, together with the experience in project management, GLYCOVAX will create a multidisciplinary environment where 14 young researchers will contribute to develop a novel route towards improved, safer and better characterized glycoconjugate vaccines, and contemporarily acquire transferable skills which will lead them to become the new leaders of academic or industrial research. The network will involve 9 academic groups and 2 industrial partners as Beneficiaries, and one SME as Partner Organization. The profound interaction between academy and industry will aid the students to get new concepts and visions for translating their ideas from the bench to the manufacturing of the next generation of glycoconjugate vaccines.", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Italy"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-11-01"], "Project_ID": ["675671"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["BILKENT UNIVERSITESI VAKIF"], "EU_Contribution": ["EUR 145 845,60"], "Project_Title": ["3D Silicon Micromachining with Infrared ultrafast LasErs"], "Total_Cost": ["EUR 145 845,60"], "Country": ["Turkey"], "Project_ACR": ["SMILE"], "Technology_Description": "The aim of the present proposal is to initiate an interdisciplinary research program to develop 3D micromachining of silicon towards novel silicon photonics and microfluidic applications. We are motivated by the myriad of applications based on 3D micromachining of glass that peaked in the early 2000's, and still continues to impact integrated photonics and microfluidics, among other fields. These successes were achieved using lasers at wavelengths for which glass is transparent (most commonly 1 um, 800 nm and their second harmonics). Most of the important results demonstrated in glass can be carried over to silicon using a long-wavelength laser (beyond 1.1 um, silicon is highly transparent), though it is clear that the physics will be different, not least because glass is amorphous and silicon is crystalline. To this end, we propose an interdisciplinary research effort that includes first developing the necessary laser technology, then building up the physical understanding, and finally pursuing high impact applications. Our approach can be summarized as:", "To": ["2017-09-29, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Turkey"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-30"], "Project_ID": ["660769"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["DIGITAL RESEARCH INFRASTRUCTURE FOR THE ARTS AND HUMANITIES", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW", "GEORG-AUGUST-UNIVERSITAT GOTTINGENSTIFTUNG OFFENTLICHEN RECHTS"], "EU_Contribution": ["EUR 1 930 139"], "Project_Title": ["Humanities at Scale: Evolving the DARIAH-ERIC"], "Total_Cost": ["EUR 1 941 576,25"], "Country": ["France", "France", "Netherlands", "Germany"], "Project_ACR": ["HaS-DARIAH"], "Technology_Description": "The \u2018Humanities at Scale\u2019 project will further the DARIAH ERIC\u2019s aim to integrate digitally enabled research in the arts and humanities in Europe and beyond and to operate a platform to enable trans-national arts and humanities research. The project will help DARIAH sustain existing knowledge in digital arts and humanities in Europe and enable new one. DARIAH connects various hubs of excellence in the domain and helps them share their results and innovations. By sharing knowledge, DARIAH works proactively to enhance the reach of digital arts and humanities within the European Research Area (ERA). This proposals aims to address some critical limitations of the current model of sharing knowledge in DARIAH and of connecting the national services in digital arts and humanities initiatives in Europe.", "To": ["2017-12-31, closed project"], "Meta": [""], "Topic_s": ["INFRADEV-3-2015 - Individual implementation and operation of ESFRI projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["675570"], "Call_for_Proposal": ["H2020-INFRADEV-1-2015-1"]}, -{"Partners": ["THE UNIVERSITY OF LIVERPOOL", "AMSTERDAM SCIENTIFIC INSTRUMENTS BV", "EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH", "FONDAZIONE CENTRO NAZIONALE DI ADROTERAPIA ONCOLOGICA", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "GSI HELMHOLTZZENTRUM FUER SCHWERIONENFORSCHUNG Gmbh", "ION BEAM APPLICATIONS SA", "LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN", "EBG (Entwicklungs- und Betriebsgesellschaft) MedAustron GmbH", "PAUL SCHERRER INSTITUT", "UNIVERSITY COLLEGE LONDON", "THE UNIVERSITY OF MANCHESTER", "UNIVERSIDAD DE SEVILLA", "VIALUX MESSTECHNIK + BILDVERARBEITUNG GMBH"], "EU_Contribution": ["EUR 3 871 703,52"], "Project_Title": ["Optimization of Medical Accelerators"], "Total_Cost": ["EUR 3 871 703,52"], "Country": ["United Kingdom", "Netherlands", "Switzerland", "Italy", "Spain", "Germany", "Belgium", "Germany", "Austria", "Switzerland", "United Kingdom", "United Kingdom", "Spain", "Germany"], "Project_ACR": ["OMA"], "Technology_Description": "Cancer is a major social problem, and it is the main cause of death between the ages 45-65 years. In the treatment of cancer, radio therapy (RT) plays an essential role. RT with hadrons (protons and light ions), due to their unique physical and radiobiological properties, offers several advantages over photons for specific cancer types. In particular, they penetrate the patient with minimal diffusion, they deposit maximum energy at the end of their range, and they can be shaped as narrow focused and scanned pencil beams of variable penetration depth. Although significant progress has been made in the use of particle beams for cancer treatment, an extensive research and development program is still needed to maximize the healthcare benefits from these therapies. ", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-02-01"], "Project_ID": ["675265"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["EUROPEAN SOUTHERN OBSERVATORY - ESO EUROPEAN ORGANISATION FOR ASTRONOMICAL RESEARCH IN THE SOUTHERN HEMISPHERE", "EUROPEAN SOUTHERN OBSERVATORY - ESO EUROPEAN ORGANISATION FOR ASTRONOMICAL RESEARCH IN THE SOUTHERN HEMISPHERE"], "EU_Contribution": ["EUR 1 999 250"], "Project_Title": ["Globular clusters as living fossils of the past of galaxies"], "Total_Cost": ["EUR 1 999 250"], "Country": ["Germany", "Germany"], "Project_ACR": ["ArcheoDyn"], "Technology_Description": "Globular clusters (GCs) are enigmatic objects that hide a wealth of information. They are the living fossils of the history of their native galaxies and the record keepers of the violent events that made them change their domicile. This proposal aims to mine GCs as living fossils of galaxy evolution to address fundamental questions in astrophysics: (1) Do satellite galaxies merge as predicted by the hierarchical build-up of galaxies? (2) Which are the seeds of supermassive black holes in the centres of galaxies? (3) How did star formation originate in the earliest phases of galaxy formation? To answer these questions, novel population-dependent dynamical modelling techniques are required, whose development the PI has led over the past years. This uniquely positions him to take full advantage of the emerging wealth of chemical and kinematical data on GCs.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["724857"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSITY OF GLASGOW", "THE UNIVERSITY OF MANCHESTER", "MEDIZINISCHE HOCHSCHULE HANNOVER", "UNIVERSITAETSKLINIKUM HEIDELBERG", "OULUN YLIOPISTO", "MOSAIQUES DIAGNOSTICS GMBH", "ACQUIFER AG"], "EU_Contribution": ["EUR 3 137 377,32"], "Project_Title": ["Development and disease of the renal tract"], "Total_Cost": ["EUR 3 137 377,32"], "Country": ["France", "United Kingdom", "United Kingdom", "Germany", "Germany", "Finland", "Germany", "Germany"], "Project_ACR": ["RENALTRACT"], "Technology_Description": "The renal tract (kidneys, the ureters, bladder) is a complex organ system crucial for maintaining the body homeostasis. This organ system arises from different precursor pools through a complex program of patterning, differentiation and morphogenesis in embryonic development. Alteration of this program leads to renal tract malformations (RTM) that are incompatible with a healthy life. While some of these RTM can be surgically corrected, others develop into chronic entities that may lead to renal failure; the burden for the patients and for the socio-economic impact for the health systems is immense. Although congenital RTM are amongst the most frequent human birth defects, the different programs that direct normal and pathological development have remained poorly understood. ", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-06-01"], "Project_ID": ["642937"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER", "DEIMOS CASTILLA LA MANCHA SL", "GOMSPACE APS", "UNIVERSITAET STUTTGART", "UNIVERSITAT POLITECNICA DE CATALUNYA", "UNIVERSITY COLLEGE LONDON", "THE TECH TOYBOX, INC.", "EUROCONSULT SA", "Concentris Research Management GmbH"], "EU_Contribution": ["EUR 5 726 750"], "Project_Title": ["DISCOVERER \u2013 DISruptive teChnOlogies for VERy low Earth oRbit platforms"], "Total_Cost": ["EUR 5 726 750"], "Country": ["United Kingdom", "Spain", "Denmark", "Germany", "Spain", "United Kingdom", "United States", "France", "Germany"], "Project_ACR": ["DISCOVERER"], "Technology_Description": "We envision a radical redesign of Earth observation platforms for sustained operation at significantly lower altitudes than the current state of the art, using a combination of new aerodynamic materials, aerodynamic control and air-breathing electric propulsion for drag-compensation, for a variety of observation methods with the aim of creating a new platform paradigm.", "To": ["2021-03-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-01-2016-2017 - FET-Open research and innovation actions"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["737183"], "Call_for_Proposal": ["H2020-FETOPEN-1-2016-2017"]}, -{"Partners": ["BILKENT UNIVERSITESI VAKIF"], "EU_Contribution": ["EUR 145 845,60"], "Project_Title": ["Energy Efficient FPGA Accelerators for Graph Analytics Applications"], "Total_Cost": ["EUR 145 845,60"], "Country": ["Turkey"], "Project_ACR": ["FPGA Accelerators"], "Technology_Description": "It is reported that data centers today consume up to 3 percent of the global electricity usage. This is expected to increase in the upcoming years as the amount of data processed in the cloud increases substantially. An effective way for data centers to achieve better performance and energy efficiency is to perform computation on specialized processing elements. Field programmable gate arrays (FPGAs) enable customization of logic after manufacturing to achieve better energy efficiency compared to general purpose processors. Today, prominent hardware and software companies are investing in data center solutions that integrate FPGAs with CPUs, and significant energy consumption and performance improvements have been demonstrated for several data center applications. However, the main barrier for wide spread adoption of FGPAs in data centers is the cost of programming, which typically requires months of development time by hardware designers. This makes it unaffordable for small-to-medium software companies to effectively utilize the available FPGAs. The purpose of this project is to lower this barrier for emerging graph analytics applications for knowledge discovery and machine learning. The basic idea is to use an abstract interface that allows a domain expert to describe an application as a set of serial functions defined per vertex and/or edge. We propose a customizable implementation template that automatically maps the abstract user functions to massively parallel FPGA implementations. The proposed template will hide from users many low level implementation details such as parallelization, pipelining, synchronization, memory access optimization, race and deadlock avoidance, etc. This will help bridge the gap between high level application descriptions and costly hardware implementations. Our preliminary architecture simulations have shown that the proposed graph processors can achieve significantly better energy efficiency than general purpose processors.", "To": ["2018-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Turkey"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-04-01"], "Project_ID": ["704476"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["KUNGLIGA TEKNISKA HOEGSKOLAN", "UNIVERSITEIT UTRECHT", "FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)", "FORSCHUNGSZENTRUM JULICH GMBH", "THE UNIVERSITY OF EDINBURGH", "THE UNIVERSITY OF MANCHESTER", "EUROPEAN MOLECULAR BIOLOGY LABORATORY", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "FORWARD TECHNOLOGIES AB", "BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION", "IAN HARROW CONSULTING LTD"], "EU_Contribution": ["EUR 4 782 286"], "Project_Title": ["Centre of Excellence for Biomolecular Research"], "Total_Cost": ["EUR 4 782 286,25"], "Country": ["Sweden", "Netherlands", "Spain", "Germany", "United Kingdom", "United Kingdom", "Germany", "Germany", "Sweden", "Spain", "United Kingdom"], "Project_ACR": ["BioExcel"], "Technology_Description": "Life Science research has become increasingly digital, and this development is accelerating rapidly. Biomolecular modelling techniques such as homology modelling, docking, and molecular simulation have advanced tremendously due to world-leading European research, resulting in extreme demands for better computational performance and throughput as these tools are used in applied research and industrial development. This research has direct influence on our daily life in areas such as health and medical applications, the development of new drugs, efficient drug delivery, biotechnology, environment, agriculture and food industry. Life Science is one of the largest and fastest growing communities in need of high-end computing, and it is a critically important industrial sector for Europe. However, compared to some other disciplines, the use of e-Infrastructure is still relatively new - many advanced techniques are not applied commercially due to limited experience. It requires significant support to:", "To": ["2018-10-31, ongoing project |"], "Meta": [""], "Topic_s": ["EINFRA-5-2015 - Centres of Excellence for computing applications"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-11-01"], "Project_ID": ["675728"], "Call_for_Proposal": ["H2020-EINFRA-2015-1"]}, -{"Partners": ["BILKENT UNIVERSITESI VAKIF", "BILKENT UNIVERSITESI VAKIF"], "EU_Contribution": ["EUR 1 995 625"], "Project_Title": ["Graphene based smart surfaces: from visible to microwave"], "Total_Cost": ["EUR 1 995 625"], "Country": ["Turkey", "Turkey"], "Project_ACR": ["SmartGraphene"], "Technology_Description": "The aim of this proposal is to develop adaptive camouflage systems using graphene-enabled smart surfaces. We propose a new class of active surfaces capable of real-time electrical-control of its appearance in a very broad spectrum ranging from visible to microwave covering 6 orders of magnitude in wavelength. The proposed method relies on controlling electromagnetic waves by tuning density of high-mobility charges on single or multilayers of atomically thin graphene electrodes. We will realize this goal by efficient gating of large-area graphene using ionic liquids which yields unprecedented ability to control intensity and phase of the reflected and transmitted electromagnetic waves from the surface. Based on underlying physical mechanisms and applications, the proposed research plan is structured in 3 main directions; (1) Active surfaces in microwave and THz, (2) Active thermal surfaces, and (3) Active surfaces in the visible. ", "To": ["2021-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Turkey"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["682723"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["BILKENT UNIVERSITESI VAKIF"], "EU_Contribution": ["EUR 157 845,60"], "Project_Title": ["\u201cThe Role of Urbanization in Female Empowerment: the Turkish Case in Comparative Perspective\u201d"], "Total_Cost": ["EUR 157 845,60"], "Country": ["Turkey"], "Project_ACR": ["Female Empowerment"], "Technology_Description": "Female empowerment is perceived both as a policy tool for the betterment of overall welfare of the societies, as well as a policy target both in Europe and throughout the world. However, women still lag behind men in education, economic affluence, and political representation in many countries, even in some of the most \u201cdeveloped\u201d ones. The proposed project aims to shed light on the dynamics behind female empowerment, specifically focusing on the role of urbanization. Modernization and industrialization bring about several advantages for many women such as better education and livelihoods, better say for themselves and their children, and fairer political representation. Yet, urbanization remains insufficient to eradicate the extant problems that women have faced and creates new challenges and obstacles for many. The proposed project argues that female empowerment is a multi-faceted, multi-level phenomenon that calls for such a research strategy and hypothesizes that urbanization has a complex, non-linear effect on female empowerment. To better understand the concept at hand and pinpoint the ways to enhance it, the project incorporates country-, local-, and individual-levels of analysis. The project also combines the strengths of quantitative and qualitative techniques to offer a fuller picture about female empowerment. The main focus of the project is the relationship between urbanization and female empowerment in Turkey, while it also provides a comparative global-level analysis with clear implications for Europe. The proposed research aims to make novel contributions to the feminist studies, urban studies, development studies, and democratization literatures and enhance the competitiveness of European research. In addition to its academic merit, the project also has policy implications aimed at policymakers for future policies and projects, as well as the society at large which could be implemented throughout Europe.", "To": ["2018-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Turkey"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-04-01"], "Project_ID": ["702073"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN", "MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN"], "EU_Contribution": ["EUR 1 993 421"], "Project_Title": ["DNA end protection in Immunity and Cancer"], "Total_Cost": ["EUR 1 993 421"], "Country": ["Germany", "Germany"], "Project_ACR": ["DNAendProtection"], "Technology_Description": "This proposal addresses a fundamental issue in molecular biology: how is repair of DNA double-strand breaks (DSBs) steered towards the appropriate physiological outcome? DSBs are cytotoxic DNA lesions that arise as a by-product of DNA replication, but also as a physiological intermediate during antigen receptor diversification in the Immune system. DNA end processing is a major determinant of DSB repair outcome. Resection of DNA ends is a prerequisite for physiological repair of replication-associated breaks by homologous recombination, but detrimental for productive end-joining events during immunoglobulin class switch recombination (CSR) in B lymphocytes. Furthermore, inappropriate resection of DSBs can cause loss of genetic information and chromosome deletions, which are common features of cancer genomes.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2015-09-01"], "Project_ID": ["638897"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN", "MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN"], "EU_Contribution": ["EUR 1 999 877"], "Project_Title": ["Neural mechanisms of multisensory perceptual binding"], "Total_Cost": ["EUR 1 999 877"], "Country": ["Germany", "Germany"], "Project_ACR": ["ACoolTouch"], "Technology_Description": "Sensory perception involves the discrimination and binding of multiple modalities of sensory input. This is especially evident in the somatosensory system where different modalities of sensory input, including thermal and mechanosensory, are combined to generate a unified percept. The neural mechanisms of multisensory binding are unknown, in part because sensory perception is typically studied within a single modality in a single brain region. I propose a multi-level approach to investigate thermo-tactile processing in the mouse forepaw system from the primary sensory afferent neurons to thalamo-cortical circuits and behaviour.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2016-09-01"], "Project_ID": ["682422"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["THE UNIVERSITY OF NOTTINGHAM"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Simulations for multi-level Analysis of interactions in Tunnelling based on the Building Information Modelling technology"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SATBIM"], "Technology_Description": "With increasing urbanization and mobility, the need for underground facilities and consequently efficient and safe design and construction techniques grows. The goal of the SATBIM project is to develop a multi-level simulation model for tunnel-structure interaction integrated in the framework of Building Information Modelling to support engineering decisions during the project life cycle and to allow for the evaluation and minimization of risks on the existing infrastructure. SATBIM is an integrated platform for structural analysis, visualisation and optimization of the mechanized tunnelling process from early stages of the design over to the construction and the operation phase. The complete concept will be validated using industrial data with reference to the Rastatter tunnel project in Germany. The output will have wide implication on technology with expected high academic and industrial impact.", "To": ["2018-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["702874"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH", "EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH"], "EU_Contribution": ["EUR 1 463 750"], "Project_Title": ["Multi Ion Reflection Apparatus for Collinear Laser Spectroscopy of radionuclides"], "Total_Cost": ["EUR 1 463 750"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["MIRACLS"], "Technology_Description": "Employing laser spectroscopy (LS) to study radionuclides is equally rich in its long tradition as it is manifold in its active pursuit today as virtually all radioactive ion beam (RIB) facilities do or are planning to host dedicated setups. Probing the hyperfine structure of an atom or ion with laser light is a powerful technique to infer nuclear properties such as a nuclide\u2019s spin, charge radius, or electromagnetic moments. This information provides insight into a wide range of contemporary questions in nuclear physics such as the mechanism driving the emergence and disappearance of nuclear shells far away from stability.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-01-01"], "Project_ID": ["679038"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["TTY-SAATIO", "AARHUS UNIVERSITET", "UNIVERSITAT ZURICH", "THE UNIVERSITY OF MANCHESTER", "INSTITUT JOZEF STEFAN", "ALLIANCEBERNSTEIN LIMITED", "ING GROEP NV"], "EU_Contribution": ["EUR 3 463 286,40"], "Project_Title": ["Training for Big Data in Financial Research and Risk Management"], "Total_Cost": ["EUR 3 463 286,40"], "Country": ["Finland", "Denmark", "Switzerland", "United Kingdom", "Slovenia", "United Kingdom", "Netherlands"], "Project_ACR": ["BigDataFinance"], "Technology_Description": "BigDataFinance, a Marie Sk\u0142odowska-Curie Innovative Training Network \u201cTraining for Big Data in Financial Research and Risk Management\u201d, provides doctoral training in sophisticated data-driven risk management and research at the crossroads of Finance and Big Data for 13 researchers. The main objectives are i) to meet an increasing commercial demand for well-trained researchers experienced in both Big Data techniques and Finance and ii) to develop and implement new quantitative and econometric methods for empirical finance and risk management with large and complex datasets. To achieve the objectives, the emphasis is put on exploiting big data techniques to manage and use datasets that are too large and complex to process with conventional methods.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-10-01"], "Project_ID": ["675044"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN", "MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN"], "EU_Contribution": ["EUR 1 457 938"], "Project_Title": ["Safeguarding Cell Identities: Mechanisms Counteracting Cell Fate Reprogramming"], "Total_Cost": ["EUR 1 457 938"], "Country": ["Germany", "Germany"], "Project_ACR": ["REPROWORM"], "Technology_Description": "Regenerating tissues by reprogramming cells has the potential to become a therapeutic approach for replacing lost tissues in patients suffering from injury or degenerative diseases such as Alzheimer\u2019s or Muscular Dystrophy. Strategies to generate required tissues using embryonic stem cells or induced pluripotent stem cells (iPSCs) are associated with either ethical or medical safety issues. An alternative strategy is to directly reprogram cells to the required tissue type by forced expression of cell fate-inducing transcription factors (TFs). Direct reprogramming (DR) has the potential to circumvent unsafe proliferative pluripotent cell stages and it allows in vivo procedures. However to date, DR is successful in only a few cell types and it is not well understood why most cells are refractory to DR. Recently, we provided evidence that inhibitory mechanisms play an important role in restricting cell fate conversion. We identified factors inhibiting direct conversion of germ cells into specific neurons or muscle cells. Additionally, preliminary studies in our group revealed other factors that inhibit ectopic cell fate induction in somatic cells. ", "To": ["2020-02-29, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2015-03-01"], "Project_ID": ["637530"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["UNIVERSITY OF BATH", "UNIVERSITY OF BATH", "MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN", "THE UNIVERSITY OF EDINBURGH"], "EU_Contribution": ["EUR 2 497 996"], "Project_Title": ["Evolutionary genomics: new perspectives and novel medical applications"], "Total_Cost": ["EUR 2 497 996"], "Country": ["United Kingdom", "United Kingdom", "Germany", "United Kingdom"], "Project_ACR": ["EvoGenMed"], "Technology_Description": "To make for better diagnostics and safer applications of genomics we need a better understanding of our genome and how it functions. Until recently we thought we knew: intergenic sequence must be largely \u201cjunk\u201d and mutations that, for example, affect genes but not the protein (synonymous mutations) must be effectively neutral. This degenerate genome view accords with the nearly-neutral theory\u2019s prediction that selection will be weaker when populations are small. But is this all there is to it? I shall investigate two new interrelated perspectives on genome evolution. First, I suggest that to mitigate errors, owing to our high error rates, our genome can be under stronger, not weaker, selection. Second, that errors might be a source of evolutionary novelty. Error mitigation, my team has shown, often involves selection on seemingly innocuous mutations such as synonymous changes. Remarkably, we discovered that selection to ensure error-proof splicing is possibly more prevalent on synonymous mutations when populations are small, making seemingly innocuous mutations stronger candidates for human diseases. I shall provide the first test of the new error-proofing perspective through comparative genomic analysis on synonymous site evolution. To investigate error as a source of novelty I shall consider whether expression piggy-backing (expression of a gene affecting its neighbors) forces rewiring of gene networks. Importantly, I shall translate our new understanding to enable better diagnostics and improved therapeutics. I shall develop a much-needed computer package to identify candidate disease-causing synonymous changes. In addition, knowing how synonymous sites modulate splicing will allow me to design better intronless transgenes. Transgenes must also be inserted in genomic regions immune to piggy-backing. I will examine transposable element related piggy-backing to characterize \u201csafe\u201d sites for therapeutic gene insertion and mammalian transgenesis more generally.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["669207"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["MEDIZINISCHE UNIVERSITAET WIEN", "CARDIFF UNIVERSITY", "FUNDACIO SANT JOAN DE DEU", "KOBENHAVNS UNIVERSITET", "THE UNIVERSITY OF LIVERPOOL", "THE UNIVERSITY OF MANCHESTER", "UNIVERSITA DEGLI STUDI DI FIRENZE", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "UNIVERSITE DE PICARDIE JULES VERNE", "STICHTING VU", "BIOTALENTUM TUDASFEJLESZTO KFT", "S.A.F.AN. BIOINFORMATICS - SAS DI PUGLIESE LUISA", "TISSUEGNOSTICS GMBH"], "EU_Contribution": ["EUR 3 657 194,64"], "Project_Title": ["Calcium-Sensing Receptor (CaSR): Therapeutics for Non-Communicable Diseases"], "Total_Cost": ["EUR 3 657 194,64"], "Country": ["Austria", "United Kingdom", "Spain", "Denmark", "United Kingdom", "United Kingdom", "Italy", "United Kingdom", "France", "Netherlands", "Hungary", "Italy", "Austria"], "Project_ACR": ["CaSR Biomedicine"], "Technology_Description": "The calcium sensing receptor (CaSR) is a class C Gprotein-coupled receptor that plays a pivotal role in systemic calcium metabolism by regulating parathyroid hormone secretion and urinary Ca excretion. Abnormal CaSR function is implicated in calciotropic disorders, and in non-calciotropic disorders such as Alzheimer\u2019s disease (AD), cardiovascular disease (CVD), diabetes (DM), sarcopenia and cancer, which account for >25% of the global disease burden. The CaSR is a unique GPCR whose principal physiological ligand is the Ca2+ ion; it is expressed almost ubiquitously; interacts with multiple G\u03b1 subtypes regulating highly divergent downstream signalling pathways, depending on the cellular context. The CaSR Biomedicine is a fully translational project that utilises the concept of a single molecule, the CaSR, influencing a range of physiological and disease processes, to develop a unique, strong multidisciplinary and intersectoral scientific training programme preparing 14 young scientists to become specialists in GPCR biology and signalling.", "To": ["2020-02-29, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-03-01"], "Project_ID": ["675228"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["DANMARKS TEKNISKE UNIVERSITET", "THE UNIVERSITY OF MANCHESTER", "LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN", "LUNDS UNIVERSITET", "NOVOZYMES A/S", "WYATT TECHNOLOGY EUROPE GMBH", "MEDIMMUNE LIMITED", "KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 4 067 745,48"], "Project_Title": ["Protein-excipient Interactions and Protein-Protein Interactions in formulation"], "Total_Cost": ["EUR 4 067 745,48"], "Country": ["Denmark", "United Kingdom", "Germany", "Sweden", "Denmark", "Germany", "United Kingdom", "Denmark"], "Project_ACR": ["PIPPI"], "Technology_Description": "The revolution of biotechnology has led to the creation of various types of therapeutic biologics with the potential to provide treatment for new chronic and malignant diseases. Though the potential advantages of biologics lay in their high specificity and potency combined with few side effects, their formulation still remains a large challenge to pharmaceutical scientists. This is in part due to the complex, not-well understood relationship between the physicochemical properties of proteins and formulation conditions required for protein stability. A comprehensive understanding of the molecular mechanisms behind protein stabilization and solubility would provide the formulation scientists with knowledge of the interplay between formulation and stability that in turn could potentially make formulation development faster, cheaper and less labour intensive than the currently used broad screening approach. Understanding the susceptibilities of formulations to protein aggregation and denaturation can reduce the response time to for instance product failure. Few universities in Europe have formulation of biologics as a scientific subject. Consequently, the pharmaceutical industry is forced to train scientists - a challenge for larger companies, and an insurmountable task for smaller companies. Scientists in the field of structural biology, biophysics, protein formulation and stability have formed a consortium to systematically map physicochemical properties of biologics, formulation conditions and protein stability. The main objective of the consortium is to provide a new generation of innovative and entrepreneurial early-stage researchers that will develop methodologies, tools and databases to guide the formulation of robust biologics. The consortium will not only provide an excellent platform to train a new generation of formulation scientists, but also establish avenues for designing new formulation strategies and thereby securing the leading edge of EU expertise.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["675074"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN", "MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Exploring the Potential for Therapeutic Lineage Reprogramming of Diabetes"], "Total_Cost": ["EUR 150 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["TheLiRep"], "Technology_Description": "Diabetes is a degenerative disease that affects over 350 million persons worldwide. Type 1 and type 2 diabetes are associated with either destruction or dysfunction of pancreatic insulin-producing \u03b2 cells. Despite the availability of insulin as treatment to temporarily restore the glucostasis, this remedy is unable to avoid either the acute dangers of hypoglycemia or the long-term complications of hyperglycemia. Eventually, the challenge of treating diabetes centers on the replacement of pancreatic \u03b2 cells. Due to serious organ shortage for pancreas transplantation, cell-based therapy represents the most promising option and different potential sources for new \u03b2 cells are currently being explored, including embryonic stem cells and other cell types. A particularly attractive therapeutic strategy is to convert liver adult cells of diabetic patients into functional pancreatic \u03b2 cells through lineage reprogramming. Fate conversion of liver to pancreas is conceivable for numerous physiological and developmental reasons, and, possibly, suitable for future clinical applications. My ERC-funded project (ERC Starting Grant \u201cHEPATOPANCREATIC\u201d) is focused on the molecular mechanisms underlying cellular plasticity between liver and pancreatic cells. This study has led to the identification of a novel factor, whose ectopic expression converts mouse liver cells into pancreatic cells. Here, we propose a defined and focused set of measures aimed at: 1) extending these findings in human liver cells to assess whether this strategy may be exploited to develop an autologous cell-based therapy of diabetes; and 2) elaborating a solid intellectual property strategy. The \u201cTheLiRep\u201d Proof of Concept (PoC) funding will ensure the full exploitation of the ERC idea and bridge the gap between my research and the earliest stage of a marketable innovation.", "To": ["2016-10-31, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2014 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2015-05-01"], "Project_ID": ["641036"], "Call_for_Proposal": ["ERC-2014-PoC"]}, -{"Partners": ["BILKENT UNIVERSITESI VAKIF"], "EU_Contribution": ["EUR 157 845,60"], "Project_Title": ["Control of Triboelectricity from Micro to Macro as a Principle ofSticking, Particulate Contamination and ESD Prevention of Micromachines"], "Total_Cost": ["EUR 157 845,60"], "Country": ["Turkey"], "Project_ACR": ["Tribocharge"], "Technology_Description": "Microelectromechanical systems (MEMS) is the technology of micromachines up to 100 micrometers in size. In the era of minituarization, MEMS represents a huge and rapidly growing market, which will exceed $20B by 2020 and Europa constitutes about 20% of the total world market. However, the technology struggles with some problems preventing its fast development. This proposal aims to deal with those related to tribocharging (frictional electricity), which has been overlooked so far. Tribocharging is a very common event causing value losses due to electrostatic sticking and electrostatic discharging (ESD) problems in many industrial manufacturing processes such as static cling of powder materials in drug processing, ESD problems in electronics. Attempts to eliminate static electricity from solid and liquid materials includes the addition of antistatic agents to them that increases the deposition of water from ambient moisture and the addition or doping of some conducting materials e.g. carbon powder into plastics and a conductive path removes the excess electrostatic charge. However, these solutions are not generally very practical and limited by the specific applications in micro dimensions. In this proposal, we focused on the elimination of static charge that accumulates on MEMS. To eliminate static electricity from MEMS, I will use the chemical approach that we introduced (Science, 2013). Firstly, we aim to eliminate the excess static charge from polymer based (MEMS) using this approach by incorporating antistatic and anti-sticking properties to these micro devices for the first time. Secondly, ESD will be eliminated in these micro devices using the same approach based on the scavenging of excess electrostatic charges. Finally, it will be possible to extend the lifetime of these micro devices by eliminating problems such as sticking, (charged) particulate contamination due to e.g. wear, and ESD that mainly arise from tribocharging.", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Turkey"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["707643"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER", "THE UNIVERSITY OF MANCHESTER", "LANCASTER UNIVERSITY"], "EU_Contribution": ["EUR 1 456 252,50"], "Project_Title": ["New Science and Technology of Artificial Layered Structures and Devices"], "Total_Cost": ["EUR 1 456 252,50"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom"], "Project_ACR": ["MATTERDESIGN"], "Technology_Description": "The extensive and growing library of layered crystals opens up the exciting possibility of exfoliating them into single atomic layers and stacking these atomic layers back together in new sequences to fabricate a new class of artificial van der Waals solids, with novel properties and functionalities. The principal objectives of this proposal are to study the fundamental physics and chemistry of novel materials, structures and devices synthesised by assembling different two-dimensional (2D) crystals and to exploit their unique properties for diverse applications. ", "To": ["2021-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["679689"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["TECHNISCHE UNIVERSITEIT EINDHOVEN", "UNIVERSITEIT UTRECHT", "STOCKHOLMS UNIVERSITET", "LEIBNIZ-INSTITUT FUER NEUE MATERIALIEN GEMEINNUETZIGE GMBH", "THE UNIVERSITY OF MANCHESTER", "CHALMERS TEKNISKA HOEGSKOLA AB", "AKZO NOBEL PULP AND PERFORMANCE CHEMICALS AB", "SEPAREX SAS", "NANOLYTICS GMBH"], "EU_Contribution": ["EUR 3 378 227,90"], "Project_Title": ["A multiscale approach towards mesostructured porous material design"], "Total_Cost": ["EUR 3 378 227,90"], "Country": ["Netherlands", "Netherlands", "Sweden", "Germany", "United Kingdom", "Sweden", "Sweden", "France", "Germany"], "Project_ACR": ["MULTIMAT"], "Technology_Description": "MULTIMAT addresses (1) the industrial and societal need for affordable materials that have a highly defined and large porosity together with the required (mechanical, chemical and/or thermal) robustness for application in thermal insulation, catalysts, fuel cells and oil spill remediation and (2) the scientific need to better understand the mechanisms underlying the assembly of small building blocks into larger structures that are ordered hierarchally across multiple scales (\"multiscale assembly\"). Together this will contribute to achieving MULTIMAT's future aim: Understanding and ultimately steering the bottom-up construction of materials with complex hierarchical structures. ", "To": ["2020-02-29, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-03-01"], "Project_ID": ["676045"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["TELECOMMUNICATION SYSTEMS INSTITUTE", "THE QUEEN'S UNIVERSITY OF BELFAST", "STMICROELECTRONICS GRENOBLE 2 SAS", "ACCIONA CONSTRUCCION SA", "THE UNIVERSITY OF MANCHESTER", "POLITECNICO DI TORINO", "CHALMERS TEKNISKA HOEGSKOLA AB", "SYNELIXIS LYSEIS PLIROFORIKIS AUTOMATISMOU & TILEPIKOINONION MONOPROSOPI EPE"], "EU_Contribution": ["EUR 4 237 397,50"], "Project_Title": ["Energy-efficient Heterogeneous COmputing at exaSCALE"], "Total_Cost": ["EUR 4 237 397,50"], "Country": ["Greece", "United Kingdom", "France", "Spain", "United Kingdom", "Italy", "Sweden", "Greece"], "Project_ACR": ["ECOSCALE"], "Technology_Description": "In order to reach exascale performance current HPC servers need to be improved. Simple scaling is not a feasible solution due to the increasing utility costs and power consumption limitations. Apart from improvements in implementation technology, what is needed is to refine the HPC application development as well as the architecture of the future HPC systems.", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["FETHPC-1-2014 - HPC Core Technologies, Programming Environments and Algorithms for Extreme Parallelism and Extreme Data Applications"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Greece"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-10-01"], "Project_ID": ["671632"], "Call_for_Proposal": ["H2020-FETHPC-2014"]}, -{"Partners": ["INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE", "ECOLE NORMALE SUPERIEURE"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Optical strategies to investigate NMDA receptor functional diversity and its therapeutic potential"], "Total_Cost": ["EUR 185 076"], "Country": ["France", "France"], "Project_ACR": ["OptoNMDA"], "Technology_Description": "NMDA receptors (NMDARs) form a class of receptors gated by glutamate, the major neurotransmitter in the mammalian brain. These receptors play fundamental roles in synaptic transmission and plasticity. They are also involved in numerous pathologies including stroke, mental retardation or schizophrenia. NMDARs are thus targets of strong therapeutic interest. NMDARs are tetramers usually composed of two GluN1 and two GluN2 subunits encoded by four different genes (GluN2A-D), resulting in a large number of receptor subtypes having distinct anatomical, biophysical, pharmacological and signalling properties. Understanding the functional role of these individual subtypes in the brain is of great importance to develop new strategies to counteract the deleterious effects of NMDAR dysregulation. However, tools allowing targeting of a specific population of NMDARs in a given neuronal circuit are currently lacking. The OptoNMDA research programme proposes the development of an innovative optical approach to selectively enhance the activity of NMDARs containing the GluN2B subunit (GluN2B-NMDARs) in ex vivo and in vivo preparations. This approach consists in developing photo-convertible polyamine derivatives that can reversibly isomerize between an inactive and active configuration with light to act on the GluN2B-NMDAR polyamine allosteric modulating site in a precise spatio-temporal manner (opto-allostery). I will study the physiological and potential therapeutic roles of these compounds by testing their effects on synaptic transmission and plasticity and on genetic models of NMDAR hypo-function. Compared to previous studies targeting orthosteric (competitive) sites, the opto-allostery approach will allow manipulation of NMDARs in a more specific and physiological manner. This project should thus provide critical novel information on NMDARs, and more generally, on the physiology and pathology of excitatory synapses.", "To": ["2018-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2016-04-01"], "Project_ID": ["701467"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Enzymatic DNA deamination and the immunity/cancer balance"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["APOBEC"], "Technology_Description": "Genomic instability is a key hallmark of cancer. Chromosome translocations require the formation of pairs of double-strand breaks (DSB) and trans-chromosomal ligation of the broken ends. Members of the AID/APOBEC family of enzymes deaminate cytosine (C) to uracil (U) in the context of a polynucleotide substrate. Excision of the U residue from DNA produces an abasic site, leading to incision of the DNA strand containing the abasic site by the conventional base-excision repair pathway. The introduction of proximal incisions on both DNA strands can generate a DSB intermediate for chromosomal translocation. AID acts on C residues at immunoglobulin loci in activated B cells to trigger antibody gene diversification and is the only member of the AID/APOBEC family that is currently known to act physiologically on endogenous nuclear DNA. Off-target deamination by AID results in nucleotide substitutions and genomic rearrangements in B lymphocyte tumours. APOBEC1 edits mRNA transcripts in the small intestine. Liver-directed misexpression of APOBEC1 is oncogenic in transgenic mice. APOBEC3 enzymes are ubiquitously expressed and act on C residues in the cDNA viral replication intermediates as part of a host restriction pathway. APOBEC3A and APOBEC3B have been shown to be capable of causing genomic damage in mammalian cells. Access to the nucleus by APOBEC family members likely permits DNA deamination activity that introduces mutations and genomic instability during tumourigenesis. I have generated mice that harbour FLAG-tagged forms of AID, APOBEC1, APOBEC3A or APOBEC3B inserted at the ROSA26 locus, preceded by a floxed stop sequence for conditional expression. This system will be used to understand the role of cytosine deamination in tumour progression in tissue- and time-specific contexts in vivo through whole genome sequencing of tumours. The long-term goal is to initiate the development of reagents to regulate APOBEC activity in basic science and clinical oncology.", "To": ["2017-03-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations"], "From": ["2015-04-01"], "Project_ID": ["660883"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH", "THE UNIVERSITY OF MANCHESTER", "JOHANNES GUTENBERG-UNIVERSITAT MAINZ", "Advanced Accelerator Applications", "INSTITUTO SUPERIOR TECNICO", "FONDAZIONE CENTRO NAZIONALE DI ADROTERAPIA ONCOLOGICA", "KATHOLIEKE UNIVERSITEIT LEUVEN", "LEMER PAX"], "EU_Contribution": ["EUR 2 829 269,88"], "Project_Title": ["MEDICIS-produced radioisotope beams for medicine"], "Total_Cost": ["EUR 2 829 269,88"], "Country": ["Switzerland", "United Kingdom", "Germany", "France", "Portugal", "Italy", "Belgium", "France"], "Project_ACR": ["MEDICIS-PROMED"], "Technology_Description": "Pure accelerated radioisotope beams have been used for 50 years in fundamental physics R&D, e.g. for nuclear structure studies (pear shaped exotic nuclei, Nature 2013); CERN-ISOLDE plays a central role in developing accelerator technologies and fostering collaborative approaches to advance this field of isotope mass separation online. Our most recent contribution was the use of nanomaterial targets for more intense and reliable beam production, and laser ion sources for their purification (discovery of yet unknown 233Francium).", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Switzerland"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-04-01"], "Project_ID": ["642889"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["POLITECNICO DI TORINO", "ECOLE NATIONALE SUPERIEURE DE CHIMIE DE MONTPELLIER"], "EU_Contribution": ["EUR 139 500"], "Project_Title": ["Synthesis and photopolymerisation of new fluorinated macromonomers for the obtaining of high performance fluoropolymers"], "Total_Cost": ["EUR 238 500"], "Country": ["Italy", "France"], "Project_ACR": ["PhotoFluo"], "Technology_Description": "The PhotoFluo project consists in a consortium of three teams (two from Europe and one from Canada) committed to work for developing novel fluoropolymers suitable for optical and electronic devices, membranes for fuel cells and Li batteries, microfluidics, and biomaterials. This ambitious goal will be achieved starting from designing new perfluoropolyalkylether building blocks (PFPAE) improving safety (not bioaccumulative like perfluoroalkylics) and having chemical inertness, flexibility in a wide temperature range, very low refractive index and wettability. PFPAE will be chain extended to tune final properties; exploiting OH functionalities, these precursors will be functionalized to make telechelic macromonomers for suitable crosslinking (via both radical and ionic processes). The polymers will be synthesized by photoinduced polymerization, chosen as an efficient and eco-friendly process: the polymer formation is fast (no more than minutes compared to hours requested by thermal processes), is solvent free, is carried out at room temperature consuming low amount of energy, permits spatial resolution, as it mainly occurs in the illuminated areas. After obtaining an original portfolio of PFPAE polymers, they will be fully characterized and tested in view of innovate applications. ", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-02-01"], "Project_ID": ["690917"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN", "ABERYSTWYTH UNIVERSITY", "LOUGHBOROUGH UNIVERSITY", "VORNIA LIMITED", "MSC.SOFTWARE LTD."], "EU_Contribution": ["EUR 931 500"], "Project_Title": ["Novel Cell Migration Assay Based on Microtissue Technology and Tissue-Specific Matrices"], "Total_Cost": ["EUR 1 053 000"], "Country": ["Ireland", "United Kingdom", "United Kingdom", "Ireland", "United Kingdom"], "Project_ACR": ["MATRIXASSAY"], "Technology_Description": "Cell migration assays are commonly used to study wound healing, cancer cell invasion, and tissue development. Problems associated with the gap closure assays typically employed are that: ", "To": ["2019-05-31, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-06-01"], "Project_ID": ["644175"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["BOURNEMOUTH UNIVERSITY", "CENTRE DE RECHERCHE DE L INSTITUT PAUL BOCUSE", "HELLENIC HEALTH FOUNDATION", "RONGE & PARTNER GMBH", "KOBENHAVNS UNIVERSITET", "UNIVERSITY OF MACEDONIA"], "EU_Contribution": ["EUR 499 500"], "Project_Title": ["Shaping Smarter Consumer Behaviour and Food Choice"], "Total_Cost": ["EUR 499 500"], "Country": ["United Kingdom", "France", "Greece", "Austria", "Denmark", "Greece"], "Project_ACR": ["FoodSMART"], "Technology_Description": "Compared to meals prepared at home, meals eaten out tend to contain more calories, total fat and saturated fat and it is here where the consumer has very little control or knowledge of the nutrient profile of the food they are eating (Bohm and Quartuccio, 2008). The positive association between the rise in consumption of food prepared outside the home and the increasing prevalence of obesity has been described as a major health and wellbeing societal challenge. Attempts to increase public awareness of appropriate ways to eat more healthily unfortunately do not seem to have led to significant changes in patterns of food purchase and consumption especially from an eating \u2018out-of-home\u2019 situation. It has become obvious that the development of effective measures for improvement requires further systematic research and a radical approach. The aim of FoodSMART is to develop an innovative technical (ICT) menu solution that enables informed consumer choice when eating out that takes into account individual characteristics (such as culture, dietary requirements and age group) as well as product (specification) and environmental cues (choice architecture and consumption setting). ", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-01-01"], "Project_ID": ["643999"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["CONSIGLIO NAZIONALE DELLE RICERCHE", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "LEIBNIZ INSTITUT FUER TROPOSPHAERENFORSCHUNG e.V.", "NATIONAL OBSERVATORY OF ATHENS", "NORSK INSTITUTT FOR LUFTFORSKNING STIFTELSE", "ILMATIETEEN LAITOS", "PAUL SCHERRER INSTITUT", "HELSINGIN YLIOPISTO", "EIDGENOSSISCHE MATERIALPRUFUNGS- UND FORSCHUNGSANSTALT", "EUROPEAN CENTRE FOR MEDIUM-RANGE WEATHER FORECASTS", "METEOROLOGISK INSTITUTT", "NATIONAL INSTITUTE OF RESEARCH AND DEVELOPMENT FOR OPTOELECTRONICS", "LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN", "JRC -JOINT RESEARCH CENTRE- EUROPEAN COMMISSION", "UNIVERSIDAD DE VALLADOLID", "UNIVERSIDAD DE GRANADA", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "KONINKLIJK NEDERLANDS METEOROLOGISCH INSTITUUT-KNMI", "CESKY HYDROMETEOROLOGICKY USTAV", "LUNDS UNIVERSITET", "THE CYPRUS INSTITUTE", "RHEINISCHES INSTITUT FUER UMWELT-FORSCHUNG AN DER UNIVERSITAET ZU KOELN E.V.", "DEUTSCHER WETTERDIENST", "UNIVERSITY OF LEEDS", "NATURAL ENVIRONMENT RESEARCH COUNCIL", "Pannon Egyetem", "B.I. Stepanov Institute of Physics of the National Academy of Sciences of Belarus", "CONSORZIO NAZIONALE INTERUNIVERSITARIO PER LE SCIENZE FISICHE DELLA MATERIA", "INSTITUTE OF NUCLEAR RESEARCH AND NUCLEAR ENERGY - BULGARIAN ACADEMY OF SCIENCES", "NATIONAL UNIVERSITY OF IRELAND GALWAY", "Instytut Geofizyki Polskiej Akademii Nauk"], "EU_Contribution": ["EUR 9 541 194,51"], "Project_Title": ["Aerosols, Clouds, and Trace gases Research InfraStructure"], "Total_Cost": ["EUR 10 126 484,54"], "Country": ["Italy", "France", "Germany", "Greece", "Norway", "Finland", "Switzerland", "Finland", "Switzerland", "United Kingdom", "Norway", "Romania", "Germany", "Belgium", "Spain", "Spain", "Spain", "Netherlands", "Czech Republic", "Sweden", "Cyprus", "Germany", "Germany", "United Kingdom", "United Kingdom", "Hungary", "Belarus", "Italy", "Bulgaria", "Ireland", "Poland"], "Project_ACR": ["ACTRIS-2"], "Technology_Description": "ACTRIS-2 addresses the scope of integrating state-of-the-art European ground-based stations for long term observations of aerosols, clouds and short lived gases capitalizing work of FP7-ACTRIS. ACTRIS-2 aims to achieve the construction of a user-oriented RI, unique in the EU-RI landscape. ", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["INFRAIA-1-2014-2015 - Integrating and opening existing national and regional research infrastructures of European interest"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Other", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2015-05-01"], "Project_ID": ["654109"], "Call_for_Proposal": ["H2020-INFRAIA-2014-2015"]}, -{"Partners": ["EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH", "TTY-SAATIO", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "KARLSRUHER INSTITUT FUER TECHNOLOGIE", "TECHNISCHE UNIVERSITAT DARMSTADT", "ISTITUTO NAZIONALE DI FISICA NUCLEARE", "UNIVERSITEIT TWENTE", "CONSORCIO PARA LA CONSTRUCCION EQUIPAMIENTO Y EXPLOTACION DEL LABORATORIO DE LUZ SINCROTRON", "CENTRO DE INVESTIGACIONES ENERGETICAS, MEDIOAMBIENTALES Y TECNOLOGICAS-CIEMAT", "SCIENCE AND TECHNOLOGY FACILITIES COUNCIL", "THE UNIVERSITY OF LIVERPOOL", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "INTER-UNIVERSITY RESEARCH INSTITUTE CORPORATION, HIGH ENERGY ACCELERATOR RESEARCH ORGANISATION", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "UNIVERSITE DE GENEVE"], "EU_Contribution": ["EUR 2 999 000"], "Project_Title": ["European Circular Energy-Frontier Collider Study"], "Total_Cost": ["EUR 3 989 842"], "Country": ["Switzerland", "Finland", "France", "France", "Germany", "Germany", "Italy", "Netherlands", "Spain", "Spain", "United Kingdom", "United Kingdom", "United Kingdom", "Japan", "Switzerland", "Switzerland"], "Project_ACR": ["EuroCirCol"], "Technology_Description": "The award of the 2013 Nobel Prize for Physics acknowledged the leading role of Europe in particle physics, which has a global community of over 10,000 scientists. To reinforce its pole position throughout the 21st century, Europe must be ready to propose an ambitious post-LHC accelerator project by 2018/19. This is one of the main recommendations of the updated European Strategy for Particle Physics, adopted by the CERN Council in May 2013.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["INFRADEV-1-2014 - Design studies"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Switzerland"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-06-01"], "Project_ID": ["654305"], "Call_for_Proposal": ["H2020-INFRADEV-1-2014-1"]}, -{"Partners": ["TECHNISCHE UNIVERSITEIT DELFT"], "EU_Contribution": ["EUR 242 929,80"], "Project_Title": ["Biocrete \u2013 Bio-inspired bacteria-based stress-responsive concrete."], "Total_Cost": ["EUR 242 929,80"], "Country": ["Netherlands"], "Project_ACR": ["Biocrete"], "Technology_Description": "The proposed project aims to develop biocrete a bio-inspired stress-responsive concrete. Biocrete will be realized through the cross-pollination of the fields of: bacteria-based self-healing concrete; and bio-inspired organic-inorganic materials synthesis. This cross-pollination will see bacteria incorporated in hydrogel systems for the formation of novel bio-inspired bacteria-activated organic-inorganic composite materials, or bio-composite materials for short. In order to develop these bio-composite materials technologies the applicant will receive advanced training in organic-inorganic materials synthesis, with a focus on calcium carbonate precipitation in polymer hydrogels. He will also master state-of-the-art organic-inorganic materials analysis techniques including serial sectioning by cryo-focused ion beam milling (cryo-FIB), and ultimately by cryo-scanning transmission electron microscopy (cryo-STEM). Such techniques will provide insights on the formation of the bio-composite materials, which will be key in ultimately controlling their morphology and mechanical properties. Biocrete will be born through the incorporation of these bio-composite materials technologies into concrete materials. Biocrete will be tested for its crack sealing and mechanical performance. It is envisaged biocrete have a superior crack healing action over conventional concrete materials, resulting in better functional performance and more durable concrete construction.", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["747736"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["INSTITUTE OF COMMUNICATION AND COMPUTER SYSTEMS", "THE UNIVERSITY OF MANCHESTER", "BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION", "FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS", "SCIENCE AND TECHNOLOGY FACILITIES COUNCIL", "INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM", "ZEROPOINT TECHNOLOGIES AB", "ICEOTOPE RESEARCH & DEVELOPMENT LTD", "ARM LIMITED", "SYNELIXIS LYSEIS PLIROFORIKIS AUTOMATISMOU & TILEPIKOINONION MONOPROSOPI EPE", "MAXELER TECHNOLOGIES LIMITED", "NEURASMUS BV", "ISTITUTO NAZIONALE DI FISICA NUCLEARE", "ISTITUTO NAZIONALE DI ASTROFISICA", "EUROPEAN CENTRE FOR MEDIUM-RANGE WEATHER FORECASTS", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V."], "EU_Contribution": ["EUR 19 949 022,50"], "Project_Title": ["Co-designed Innovation and System for Resilient Exascale Computing in Europe: From Applications to Silicon"], "Total_Cost": ["EUR 19 949 022,50"], "Country": ["Greece", "United Kingdom", "Spain", "Greece", "United Kingdom", "Belgium", "Sweden", "United Kingdom", "United Kingdom", "Greece", "United Kingdom", "Netherlands", "Italy", "Italy", "United Kingdom", "Germany"], "Project_ACR": ["EuroEXA"], "Technology_Description": "To achieve the demands of extreme scale and the delivery of exascale, we embrace the computing platform as a whole, not just component optimization or fault resilience. EuroEXA brings a holistic foundation from multiple European HPC projects and partners together with the industrial SME focus of MAX for FPGA data-flow; ICE for infrastructure; ALLIN for HPC tooling and ZPT to collapse the memory bottleneck; to co-design a ground-breaking platform capable of scaling peak performance to 400 PFLOP in a peak system power envelope of 30MW; over four times the performance at four times the energy efficiency of today\u2019s HPC platforms. Further, we target a PUE parity rating of 1.0 through use of renewables and immersion-based cooling.", "To": ["2021-02-28, ongoing project"], "Meta": [""], "Topic_s": ["FETHPC-01-2016 - Co-design of HPC systems and applications"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Greece"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["754337"], "Call_for_Proposal": ["H2020-FETHPC-2016"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET", "ASTRAZENECA AB", "UNIVERSITAETSKLINIKUM FREIBURG", "INSTITUTO DE BIOLOGIA MOLECULAR E CELULAR-IBMC", "ACADEMISCH ZIEKENHUIS LEIDEN", "MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN", "USTAV MOLEKULARNI GENETIKY AKADEMIE VED CESKE REPUBLIKY VEREJNA VYZKUMNA INSTITUCE"], "EU_Contribution": ["EUR 2 068 409,16"], "Project_Title": ["Improving Genome Editing Efficiency (IMGENE)"], "Total_Cost": ["EUR 2 068 409,16"], "Country": ["Denmark", "Sweden", "Germany", "Portugal", "Netherlands", "Germany", "Czech Republic"], "Project_ACR": ["IMGENE"], "Technology_Description": "CRISPR genome editing technology is considered to become the greatest technological improvement in biomedical research since the invention of the polymerase chain reaction 25 years ago and pharmaceutical companies as well as academic research are eager to apply it. However, the efficiency of introducing defined changes into the genome by CRISPR is still low, currently limiting its application in basic research, industry and gene therapy. IMGENE unites expert European research groups of academia and industry to address by innovative and complementary approaches the low efficiency of precise genome editing using CRISPR technology. To our best knowledge, IMGENE is the only concerted approach to tackle the important problem of low genome editing efficiency of CRISPR in a multidisciplinary, intersectorial manner. The IMGENE consortium consisting of 6 academic and 1 industrial beneficiary (AstraZeneca), 2 industrial partners (Taconic; MilliporeSigma), and the patient organization Genetic Alliance, aims to improve the genome editing efficiency of CRISPR by research training of 8 ESRs to unleash the full potential of this technology. Combining complementary knowledge on protein chemistry, molecular biology, cellular biology, viral vectors, transgenic mice, gene therapy, and bioinformatics present in the network, IMGENE will establish novel tools and protocols for improved CRISPR genome editing efficiency that will be of immediate benefit for health and life science research, the pharmaceutical industry, and the application of gene therapy. In addition, IMGENE addresses crucial ethical questions related to the application of genome editing technology in animals, plants, and humans, which have to be solved to gain acceptance by the society. By excellent research training of 8 ESRs on a scientifically and economically highly relevant topic and additional training in transferable skills, IMGENE will educate novel leaders with great career perspectives in industry and academia.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["765269"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["The role of danger signal and cellular competition in the elimination of B cells lacking the B cell receptor."], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["BCRdangerCOMPETITION"], "Technology_Description": "B cells represent a specialized population of lymphocytes responsible for adaptive immune responses and life-long immune memory. All mature B cells carry B cell receptors (BCRs) on the surface and it is through the BCR that B cells recognize foreign antigens and subsequently provide antibody responses. Acute ablation of the BCR in resting mature na\u00efve B cells in mice leads to a fast disappearance of Immunoglobulin negative (Ig-) B cells from peripheral lymphoid system. This phenomenon has been mainly explained by a \u201ctonic\u201d signal provided by the BCR, essential for B cell survival. However, there are at least two other possible, not mutually exclusive, mechanisms. In this proposal I hypothesize that i) loss of the BCR structure provides a \u201cdanger\u201d signal leading to apoptosis of Ig- B cells; ii) Ig- B cells are eliminated as a result of cellular competition with the Ig+ B cells. I will test these 2 hypothesis by i) addressing the unfolded protein response (UPR) in Ig- B cells as a possible \u201cdanger signal\u201d followed by in vivo genetic rescue experiments testing for its causality in Ig- B cell depletion; ii) I will produce pure Ig- B cell cultures, exploiting the novel system of genome editing of primary B cells, and address - in vitro and in vivo - the fitness, proliferation and differentiation capacity of Ig- B cells in presence and absence of cellular competition with Ig+ B cells. By addressing these points my work might provide a first-time evidence for the existence of \u201ca danger signal\u201d initiated in a B cell upon BCR ablation and prove its causality in Ig- B cell disappearance. On the other hand, elimination of Ig- B cells as a result of cellular competition with Ig+ B cells is a novel concept with important implications for lymphoma biology and potential clinical applications.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations"], "From": ["2017-04-01"], "Project_ID": ["752747"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Identification and validation of human proteins that control tau seeding in cell-based and in vivo models"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["Tau Seeding"], "Technology_Description": "The microtubule-associated protein tau is the most commonly misfolded protein in neurodegenerative disorders including Alzheimer\u2019s disease and other related tauopathies. These neurological illnesses are hypothesized to share a common mechanism of disease progression, where pathogenic aggregates or \u2018seeds\u2019 of the tau protein function as templates promoting misfolding of functional, soluble tau protein. Under this premise, therapeutic strategies that modulate the seeding cascade, have high potential to interfere with the disease process. ", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations"], "From": ["2017-11-01"], "Project_ID": ["752901"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["OBSERVATOIRE DE PARIS"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["High Sensitivity Matter-Wave Gravitation Sensors"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["MWGRAV"], "Technology_Description": "After more than 20 years of fundamental research, atom interferometers have reached sensitivity and ", "To": ["2018-04-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-04-15"], "Project_ID": ["660081"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Database Analysis for Evaluation of Seismic Performance Assessment Tools"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["DatA ESPerT"], "Technology_Description": "In highly industrialised regions, earthquakes severely affect societies in terms of economic, social and environmental consequences due to the complex integrated and highly sensitive industries - even in areas of medium to low seismicity like Europe. Whereas the seismic behaviour of typical building structures is broadly understood and reflected in technical guidelines and damage prognosis tools worldwide, event reports and even assessment tools for industrial facilities are scarce, mainly because affected facilities are usually not generally accessible and are, thus, not covered by reconnaissance teams. After the 2012 Earthquake in the Italian Regione Emilia-Romagna (RE-R), however, the regional government gathered very detailed data on seismic damages to more than 3000 industrial / business facilities in order to distribute financial compensations. The data was collected in an extremely comprehensive database including \u2013 besides many other aspects \u2013 type, size and location of the business as well as damage to structures, components and stored goods and costs of reconstruction. Within the proposed DatA ESPerT project, the researcher will exploit this globally unique SFINGE-database in a rigorous way, in order to develop mathematical tools to assess the seismic performance of industrial facilities and to give damage prognoses for future earthquakes. Due to the comparable socio-economic context and similar seismic hazard levels, the research results will be valid for many regions in Southern Europe. Additional aspects of the project consider the development of cost/performance curves for seismic mitigation measures and the investigation of the geographical damage distribution in relation to the seismological circumstances in the Emilia-Romagna. The work is strongly supported by RWTH Aachen, by Munich RE reinsurance company and by RE-R who assured to the researcher within an official agreement access to the confidential SFINGE-database in the project's framework.", "To": ["2019-06-15, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-16"], "Project_ID": ["743458"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Unlocking the potential of ultrahigh field 23Na magnetic resonance to quantify tissue sodium content for probing viability of the heart: where physics, biology and medicine meet"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["SODIUMMRI-4-EU"], "Technology_Description": "Cardiovascular diseases (CVD) are the leading cause of death with 60% of CVDs associated with coronary artery diseases (CAD). CAD is the major cause of myocardial infarction (MI), commonly known as heart attack, which can be life threatening and places a huge socio-economic burden on the EU. The most widely used therapy for CAD is revascularization, and myocardial viability is a determining factor and predictor for patient outcomes. Magnetic resonance imaging (MRI) has become a mainstay of clinical diagnosis, but so far has seen limited use in the study of the heart. Here I aim to unlock the potential of myocardial viability imaging with physiometabolic MRI to provide a new instrument for the diagnosis and assessment of therapy success of CAD. Therefore I propose a quantitative approach based on MRI of sodium (23Na) that will allow me to observe new features of the working heart, at a level of resolution that will be highly valuable in understanding, finely diagnosing, and designing treatments for CVD. To meet this goal I pursue the development of cutting edge sodium MRI technology. Its capacity for quantitative assessment of sodium tissue content will be validated in model systems and in healthy subjects. The clinical applicability of 23Na MRI for viability imaging will be examined in revascularized MI patients. For this purpose I will leverage the sensitivity gain inherent to ultrahigh field MRI (B0\u22657.0 T), capitalize on my outstanding expertise in the field of physiometabolic MRI and build on my interdisciplinary skills formed around MRI physics. In this project, this expertise will be taken to the next level to elucidate the progression of sodium concentration in ischemic myocardial tissue. This research will eliminate the main barriers to the study of tissue viability and will open entirely new possibilities for non-invasive, in vivo phenotyping as a tool for individualised medicine tailored to offset a major socio-economic burden on the EU induced by CVD.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["752489"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM"], "EU_Contribution": ["EUR 269 857,80"], "Project_Title": ["Stem Cell-Derived Exosomes for the treatment of Traumatic and Degenerative Eye Disease"], "Total_Cost": ["EUR 269 857,80"], "Country": ["United Kingdom"], "Project_ACR": ["EXO-EYE"], "Technology_Description": "The death and dysfunction of retinal ganglion cells (RGC) is a major cause of blindness in traumatic and degenerative ocular disease. For example, 60M people are affected by glaucoma with 4.5M becoming blind in both eyes, whilst optic neuritis affects 5/100,000 people and represents a significant problem for sufferers. RGC are the sole projection neurons and their axons make up the optic nerve, making them exquisitely sensitive to injury. As CNS neurons are irreplaceable, neuroprotective strategies are paramount to therapies aimed at preserving vision but as of yet, no such therapy exists. Current research has demonstrated significant neuroprotection by mesenchymal stem cells (MSC) including those from the bone marrow (BMSC), acting not as replacements for RGC but rather, as paracrine-mediated support cells. Clinical trials are already ongoing to test their efficacy in patients. Despite this, the exact mechanism behind their neuroprotective potential is not well understood. Recent studies have shown that exosomes, extracellular vesicles containing proteins, mRNA and miRNA may mediate much of the paracrine support offered by MSC and thus act as an easily purifiable cell-free alternative therapy for RGC neuroprotection. This proposal aims to assess the therapeutic efficacy of BMSC-derived exosomes, their characterisation and that of their RNA cargo. We will test these exosomes in animal models of traumatic (optic nerve crush) and degenerative (glaucoma) eye disease. Specifically, this proposal employs a novel strategy to promote RGC survival (relevant to ONC and glaucoma) and axon regeneration (relevant to optic nerve crush) through the use of exosomal delivery of mRNA/miRNA into injured RGC utilizing in vitro and in vivo injury models, RNAseq and CRISPR technology.", "To": ["2020-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["749346"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 146 591,10"], "Project_Title": ["Temporal delays in mathematical models of cell biology processes"], "Total_Cost": ["EUR 146 591,10"], "Country": ["United Kingdom"], "Project_ACR": ["TEMPOMATH"], "Technology_Description": "The primary aim of the action is the construction and analysis of new predictive and verifiable mathematical models that can uncover the effects of time delays upon various cell biology processes. In this timely project we aim to apply cutting edge functional differential equation techniques to interrogate a number of cell biology processes of huge current interest, including collective cell movement, tumour growth and self-organizing pattern formation. The ultimate goal of this research is to develop new mathematical ways to understand and control cell biology processes. The successful outcome of this project will be robust and experimentally testable mathematical theories that can be applied to a wide variety of biological and medical problems, whenever temporal delays are relevant.", "To": ["2019-01-09, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-10"], "Project_ID": ["748193"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["TECHNISCHE UNIVERSITEIT DELFT"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["Exploring Thermoelectric and Spintronic properties of Molecular Devices"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["TherSpinMol"], "Technology_Description": "The development of wearable and diffuse electronics has prompted a global need for converting heat into electrical power.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["748642"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["In-toto imaging of C. elegans larval development using adaptive optics light-sheet microscopy"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["Lightsheetelegans"], "Technology_Description": "Our project aims to combine concepts and methodologies from biology, physics and engineering to address a fundamental question in neuroscience: how is the nervous system rewired during development transitions. The nematode C. elegans is one of the most important model organisms in neuroscience due to its relatively simple stereotypical anatomy, well-studied genetics and behavior, translucent body and nervous system, ideally suited for in-toto (in its entirety) imaging. Yet most of the knowledge available refers to adult animals, and little is known about neuronal plasticity and mechanisms of behavioral changes during development. ", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations"], "From": ["2017-03-01"], "Project_ID": ["746497"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI VERONA"], "EU_Contribution": ["EUR 164 203,80"], "Project_Title": ["Medicine, Heresy and Freedom of Thought in sixteenth-century Italy:a Network of Dissident Physicians in the Confessional Age"], "Total_Cost": ["EUR 164 203,80"], "Country": ["Italy"], "Project_ACR": ["netdis"], "Technology_Description": "I am an expert researcher on the religious and medical history of sixteenth-century Italy. Applying for a GF, supervised by professors Findlen - at Stanford - and Barbierato - at the Univr-, I will examine and interpret the link between sixteenth-century heretical thought and the rise of modern science, exploring the local, national and trans-national levels of this connection. NETDIS will use digital humanities tools to reveal the network of Italian physicians who developed non-conformist religious views. By exploring the nature, extent and function of the ties among physicians, NETDIS will inquire into the genesis of freedom of thought - which stands today at the core of European identity - as an embryonic value shared by most physicians in response to the spread of intolerance in the confessional age. This will have a positive insights for several ongoing difficulties facing the EU, such as the revival of religious violence (i.e. terrorism). Working on NETDIS I will learn innovative methodologies; I will gain new perspectives for an international career; I will write my first monograph.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["748645"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["IBM RESEARCH GMBH", "IBM RESEARCH GMBH"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Local molecular profiling of tumor tissue sections: towards personalized immunotherapy"], "Total_Cost": ["EUR 150 000"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["BioProbe-PIT"], "Technology_Description": "Cancer heterogeneity has reinforced the need for personalized treatment modalities. Pre-therapeutic diagnostic testing of heterogeneous tumors helps avoid inefficacious treatments, optimizes targeted therapy and improves quality of life. Within targeted therapy, immunotherapy has led to significant improvements in treatment outcomes and is swiftly being integrated in diagnostic workflows. In this context, routine diagnostic tests currently do not exist, and treatments are further challenged by heterogeneity. Spatially resolved molecular probing of tumors prior to treatment would allow prediction of patient response to immunotherapeutics.", "To": ["2018-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-08-01"], "Project_ID": ["727761"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM", "THE UNIVERSITY OF BIRMINGHAM"], "EU_Contribution": ["EUR 1 952 373,99"], "Project_Title": ["Creating an Alternative umma: Clerical Authority and Religio-political Mobilisation in Transnational Shii Islam"], "Total_Cost": ["EUR 1 952 373,99"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["ALTERUMMA"], "Technology_Description": "This interdisciplinary project investigates the transformation of Shii Islam in the Middle East and Europe since the 1950s. The project examines the formation of modern Shii communal identities and the role Shii clerical authorities and their transnational networks have played in their religio-political mobilisation. The volatile situation post-Arab Spring, the rise of militant movements such as ISIS and the sectarianisation of geopolitical conflicts in the Middle East have intensified efforts to forge distinct Shii communal identities and to conceive Shii Muslims as part of an alternative umma (Islamic community). The project focusses on Iran, Iraq and significant but unexplored diasporic links to Syria, Kuwait and Britain. In response to the rise of modern nation-states in the Middle East, Shii clerical authorities resorted to a wide range of activities: (a) articulating intellectual responses to the ideologies underpinning modern Middle Eastern nation-states, (b) forming political parties and other platforms of socio-political activism and (c) using various forms of cultural production by systematising and promoting Shii ritual practices and utilising visual art, poetry and new media.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["724557"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN", "MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN"], "EU_Contribution": ["EUR 1 499 883"], "Project_Title": ["Quantitative analysis of variability and robustness in spatial pattern formation"], "Total_Cost": ["EUR 1 499 883"], "Country": ["Germany", "Germany"], "Project_ACR": ["SPACEVAR"], "Technology_Description": "During embryonic development a single cell turns into a complex organism. This process is characterized by an antagonism between variation and stability. On the one hand, development is a tightly controlled process; tissues need to be specified at the right time, at the correct spatial position, and with a defined size. On the other hand, regulation should not be too rigid, since embryos need to adjust to environmental perturbations and correct errors caused by noisy gene expression. We will study variation and stability during pattern formation in the zebrafish heart. We seek to understand the origin of embryo-to-embryo variability as well as robustness against perturbation.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-01-01"], "Project_ID": ["715361"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN", "MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN"], "EU_Contribution": ["EUR 2 043 804,98"], "Project_Title": ["Thermal Magnetic Resonance: A New Instrument to Define the Role of Temperature in Biological Systems and Disease for Diagnosis and Therapy"], "Total_Cost": ["EUR 2 043 804,98"], "Country": ["Germany", "Germany"], "Project_ACR": ["ThermalMR"], "Technology_Description": "Temperature is a physical parameter with diverse biological implications and crucial clinical relevance. With an ever increasing interest in thermal applications, non-invasive in vivo methods to modulate temperature and characterize subsequent effects are imperative. Magnetic resonance (MR) is a mainstay of diagnosis but lacks inherent means for focal thermal modulation.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["743077"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN", "OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN"], "EU_Contribution": ["EUR 1 713 352,50"], "Project_Title": ["Levels and Trends of Health Expectancy: Understanding its Measurement and Estimation Sensitivity"], "Total_Cost": ["EUR 1 713 352,50"], "Country": ["Austria", "Austria"], "Project_ACR": ["LETHE"], "Technology_Description": "Better health is central to human happiness and wellbeing. It also contributes substantially to economic progress, as healthy populations live longer and are more productive. Accordingly, the EU defined the improvement of health as a fundamental element of its \u201cEurope 2020\u201d strategy. The corresponding public health policies are assessed on the basis of a structural indicator for \u201cHealth Expectancy\u201d (HE). Unfortunately, HE estimates are extremely sensitive to certain methodological issues of which many are widely ignored. First, the common measurement of population health by the responses to specific survey questions is ambiguous. As a consequence, statistics on levels and trends of HE vary significantly depending on the underlying survey data and health indicators. Almost completely unrecognized is a second problem: HE estimates are also highly sensitive to particular technical features, e.g. the age range and partitioning selected for analysis and the technique chosen to add the health dimension to the life table. The efforts that have been hitherto undertaken to improve the estimation of HE focus primarily on the measurement of health with surveys, whereas the effects of the chosen HE indicator, data and method remain largely unexplored. The central aim of LETHE is to fill these gaps through a systematic exploration of the HE indicator\u2019s sensitivity to these issues. To emphasize the empirical significance of the proposed research, the effects will be investigated in the context of some major actual research questions, in particular the \u201ccompression versus expansion of morbidity\u201d debate and the differences in HE between European populations and subpopulations. Finally, the project aims to identify the particular health measure that is most strongly associated with people\u2019s actual happiness. These innovative approaches feature the potential to provide not only new insights into the levels and trends of HE, but also about its main drivers and causation mechanisms.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Austria"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["725187"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN", "MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN"], "EU_Contribution": ["EUR 149 948"], "Project_Title": ["SMALL MOLECULES TO TREAT METABOLIC SYNDROME"], "Total_Cost": ["EUR 149 948"], "Country": ["Germany", "Germany"], "Project_ACR": ["PREVMETSYN"], "Technology_Description": "SMALL MOLECULES TO TREAT METABOLIC SYNDROME", "To": ["2018-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-01-01"], "Project_ID": ["727726"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "BERGISCHE UNIVERSITAET WUPPERTAL", "KARLSRUHER INSTITUT FUER TECHNOLOGIE", "FORSCHUNGSZENTRUM JULICH GMBH", "PAUL SCHERRER INSTITUT", "FUNDACION CENTRO DE ESTUDIOS AMBIENTALES DEL MEDITERRANEO", "LEIBNIZ INSTITUT FUER TROPOSPHAERENFORSCHUNG e.V.", "UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK", "ITA-SUOMEN YLIOPISTO", "FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS", "ISTITUTO NAZIONALE DI FISICA NUCLEARE", "UNIVERSITATEA ALEXANDRU IOAN CUZA DIN IASI", "UNIVERSITY OF LEEDS", "HELSINGIN YLIOPISTO"], "EU_Contribution": ["EUR 8 941 289,64"], "Project_Title": ["Integration of European Simulation Chambers for Investigating Atmospheric Processes \u2013 Towards 2020 and beyond"], "Total_Cost": ["EUR 9 289 955,24"], "Country": ["France", "Germany", "Germany", "Germany", "Switzerland", "Spain", "Germany", "Ireland", "Finland", "Greece", "Italy", "Romania", "United Kingdom", "Finland"], "Project_ACR": ["EUROCHAMP-2020"], "Technology_Description": "Atmospheric simulation chambers are the most advanced tools for elucidating processes that occur in the atmosphere. They lay the foundations for air quality and climate models and also aid interpretation of field measurements. EUROCHAMP-2020 will further integrate the most advanced European atmospheric simulation chambers into a world-class infrastructure for research and innovation. A co-ordinated set of networking activities will deliver improved chamber operability across the infrastructure, as well as standard protocols for data generation and analysis. Outreach and training activities will foster a strong culture of cooperation with all stakeholders and users. Collaborative links will be established with other environmental research infrastructures to promote integration and sustainability within the European Research Area. Cooperation with private sector companies will be actively promoted to exploit the innovation potential of the infrastructure by supporting development of scientific instruments, sensor technologies and de-polluting materials. Trans-national access will be extended to sixteen different chambers and four calibration centres. A new, upgraded data centre will provide virtual access to a huge database of experimental chamber data and advanced analytical resources. Joint research activities will enhance the capability of the infrastructure to provide improved services for users. Measurement techniques and experimental protocols will be further developed to facilitate new investigations on climate change drivers, impacts of air quality on health and cultural heritage, while also stimulating trans-disciplinary research. Advanced process models will be developed for interpretation of chamber experiments and wider use in atmospheric modelling. Overall, EUROCHAMP-2020 will significantly enhance the capacity for exploring atmospheric processes and ensure that Europe retains its place as the world-leader in atmospheric simulation chamber research.", "To": ["2020-11-30, ongoing project"], "Meta": [""], "Topic_s": ["INFRAIA-01-2016-2017 - Integrating Activities for Advanced Communities"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-12-01"], "Project_ID": ["730997"], "Call_for_Proposal": ["H2020-INFRAIA-2016-1"]}, -{"Partners": ["MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN", "MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Glioblastoma Subtype Avatar models for Target Discovery and Biology"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["iGBMavatars"], "Technology_Description": "The Glioblastoma Multiforme (GBM) is the most common primary brain tumor and it is incurable. Two major challenges affect GBM clinical management: its heterogeneity (which treatment will best fit this very patient?) and its resistance to available treatments (will the patient benefit in any way from the chosen therapy?). Here we approach these questions with a personalized entry point. First, we aim to create \u201chumanized\u201d experimental models of GBM accurately reflecting patients at molecular level. These GBM Subtype Avatars models (GSA) will be exploited as \u201ctargeted patients\u201d in personalized biology and intervention studies. Since GBM exists as molecular subtypes with similar histopathology but mutually exclusive genetic lesions and molecular features, we will generate GSA by targeting mutations recurrently associated with Proneural, Classical or Mesenchymal GBM subtypes into adult human neural stem cells (NSC). Evidence supports that these cells can give rise to high-grade gliomas when engineered with the appropriate genetic lesions. Next, engineered NSC will be orthotopically implanted into immunocompromised rats and the resulting tumors profiled for gene expression, DNA methylation and copy number aberrations. These profiles will be compared to those generated in patient-derived xenografts and biopsies. Second, to identify drug targets favoring patients\u2019 response to the current standard of care, we will exploit GSA for state-of-art genetic screens in vivo. Specifically, we will seek for synthetic lethal interactions between DNA damaging agents and the GSA transcriptome using an in vivo CRISPRi screening approach. Third, to investigate the molecular basis of GBM heterogeneity in GSA models, we will combine genetic and immunophenotypic tracing with gene expression and epigenomic profiling. Identifying tumor-specific vulnerabilities in a dismal disease urging for effective therapies and its molecular fingerprinting convey conceivably rapid Translation in Oncology.", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-07-01"], "Project_ID": ["714922"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["JOINT INSTITUTE FOR VERY LONG BASELINE INTERFEROMETRY AS A EUROPEAN RESEARCH INFRASTRUCTURE CONSORTIUM (JIV-ERIC)", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CHALMERS TEKNISKA HOEGSKOLA AB", "DEPARTMENT OF SCIENCE AND TECHNOLOGY", "ISTITUTO NAZIONALE DI ASTROFISICA", "MINISTERIO DE FOMENTO", "SKA ORGANISATION", "STICHTING ASTRON, NETHERLANDS INSTITUTE FOR RADIO ASTRONOMY", "STICHTING INTERNATIONAL LOFAR TELESCOPE", "TECHNISCHE UNIVERSITAET MUENCHEN", "UNIVERSITY OF LEEDS", "THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 2 983 682,50"], "Project_Title": ["Joining up Users for Maximising the Profile, the Innovation and the Necessary Globalisation of JIVE"], "Total_Cost": ["EUR 3 312 308,59"], "Country": ["Netherlands", "France", "Sweden", "South Africa", "Italy", "Spain", "United Kingdom", "Netherlands", "Netherlands", "Germany", "United Kingdom", "United Kingdom"], "Project_ACR": ["JUMPING JIVE"], "Technology_Description": "\u201cJoining up Users for Maximising the Profile, the Innovation and the Necessary Globalisation of JIVE\u201d (JUMPING JIVE) aims to prepare and position European Very Long Baseline Interferometry (VLBI) for the SKA era, and to secure the role of JIV-ERIC in the European and global landscape of Research Infrastructures. ", "To": ["2021-01-31, ongoing project"], "Meta": [""], "Topic_s": ["INFRADEV-03-2016-2017 - Individual support to ESFRI and other world-class research infrastructures"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Netherlands"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-12-01"], "Project_ID": ["730884"], "Call_for_Proposal": ["H2020-INFRADEV-2016-1"]}, -{"Partners": ["MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN", "JUSTUS-LIEBIG-UNIVERSITAET GIESSEN", "UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA", "FUNDACIO CENTRE DE REGULACIO GENOMICA", "THE HEBREW UNIVERSITY OF JERUSALEM", "AARHUS UNIVERSITET", "UNIVERSITAIR MEDISCH CENTRUM UTRECHT", "QIAGEN AARHUS AS"], "EU_Contribution": ["EUR 3 870 807,84"], "Project_Title": ["circular RNA Biology Training Network: from biogenesis to biomarkers"], "Total_Cost": ["EUR 3 870 807,84"], "Country": ["Germany", "Germany", "Italy", "Spain", "Israel", "Denmark", "Netherlands", "Denmark"], "Project_ACR": ["circRTrain"], "Technology_Description": "CircRTrain focuses on circular RNAs (circRNAs), a new large class of single-stranded RNAs with covalently closed ends. CircRNAs have only very recently attracted high general interest and become the focus of an increasing number of publications: recent discoveries through sequencing technology and computational analyses have revealed the widespread existence of circRNAs in animal cells. Particularly in neural tissues, circRNA expression is high, dynamic, and evolutionarily conserved. In aging animal brains the expression of certain circRNAs is strongly elevated, suggesting connections to age-related diseases. The study of circRNAs thus emerges as a novel topic with highest importance for the understanding of such diverse conditions as neurodegenerative diseases, aging, and cancer. Moreover, the highly stable expression and their presence in human blood and exosomes make circRNAs attractive biomarker candidates. ", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["721890"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["KATHOLIEKE UNIVERSITEIT LEUVEN", "KATHOLIEKE UNIVERSITEIT LEUVEN", "UNIVERSITAET BERN"], "EU_Contribution": ["EUR 1 044 000"], "Project_Title": ["Homo Mimeticus: Theory and Criticism"], "Total_Cost": ["EUR 1 044 000"], "Country": ["Belgium", "Belgium", "Switzerland"], "Project_ACR": ["HOM"], "Technology_Description": "Mimesis is one of the most influential concepts in Western thought. Originally invoked to define humans as the \u201cmost imitative\u201d creatures in classical antiquity, mimesis (imitation) has recently been at the centre of theoretical debates in the humanities, social sciences, and the neurosciences concerning the role of \u201cmimicry,\u201d \u201cidentification,\u201d \u201ccontagion,\u201d and \u201cmirror neurons\u201d in the formation of subjectivity. And yet, despite the growing confirmations that imitation is constitutive of human behaviour, mimesis still tends to be confined to the sphere of realistic representation. The HOM project combines approaches that are usually split in different areas of disciplinary specialization to provide a correction to this tendency.", "To": ["2021-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-11-01"], "Project_ID": ["716181"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER", "UNIVERSITY OF DURHAM", "UNIVERSITY OF GLASGOW", "GEORG-AUGUST-UNIVERSITAT GOTTINGENSTIFTUNG OFFENTLICHEN RECHTS", "KARLSRUHER INSTITUT FUER TECHNOLOGIE", "UNIVERSITE CATHOLIQUE DE LOUVAIN", "LUNDS UNIVERSITET", "UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 3 930 753,09"], "Project_Title": ["Innovative Network for Monte Carlo Event Generators for LHC Physics"], "Total_Cost": ["EUR 3 930 753,09"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom", "Germany", "Germany", "Belgium", "Sweden", "United Kingdom"], "Project_ACR": ["MCnetITN3"], "Technology_Description": "We propose a European Training Network that will provide a total of 540 ESR-months of training in Monte Carlo event generator physics and techniques, and related applications in experimental particle physics.", "To": ["2021-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["722104"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["UNIVERSITY OF STRATHCLYDE", "OTTO-VON-GUERICKE-UNIVERSITAET MAGDEBURG", "UNIVERSITE DE ROUEN NORMANDIE", "STICHTING KATHOLIEKE UNIVERSITEIT", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "THE UNIVERSITY OF MANCHESTER", "FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG", "Syncom"], "EU_Contribution": ["EUR 3 926 004,12"], "Project_Title": ["Continuous Resolution and Deracemization of Chiral Compounds by Crystallization"], "Total_Cost": ["EUR 3 926 004,12"], "Country": ["United Kingdom", "Germany", "France", "Netherlands", "Switzerland", "United Kingdom", "Germany", "Netherlands"], "Project_ACR": ["CORE"], "Technology_Description": "Industries are in need of highly skilled academically trained experts and powerful sets of tools enabling the design, control & prediction of optimized & efficient production process of future high-value products such as chiral pharmaceuticals. The CORE Network will in parallel train 15 ESRs and develop tools, approaches and methods within the area of Continuous Resolution (CORE), the process to obtain enantiopure molecules of chiral compounds.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-10-01"], "Project_ID": ["722456"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Here be Spiral DRAGNs"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["Spiral DRAGNs"], "Technology_Description": "Until recently, it was thought that large double-lobed radio sources are always hosted by massive elliptical galaxies in the local Universe and that the merger phenomenon responsible for the elliptical morphology is also responsible for triggering the AGN. Consequently, the existence of spiral galaxies that host double-lobed radio sources (\u201cspiral DRAGNs\u201d) is inconsistent with leading galaxy formation models. However, these systems have been confirmed to exist, calling into question our current understanding of galaxy formation. This project aims to establish the role of these systems in galaxy formation: either reconciling their existence with current models or challenging the idea of the standard feedback model. I propose a multi-pronged approach to this project: First, I will study the parsec-scale environment in the immediate vicinity of the AGN and determine whether properties of the central black hole in these spiral hosts are similar to those of the black holes hosted by elliptical galaxies; Second, I will study the megaparsec-scale environment of spiral DRAGNs to determine whether their environment is responsible for their unique nature. I will achieve the first science goal using Very Long Baseline Interferometry (VLBI) radio observations. I will achieve the second science goal using a combination of archival and new data at multiple wavelengths. Together these two science goals will enable us to definitively determine whether spiral DRAGNs are a result of the intrinsic properties of the black hole, a result of their large-scale environment, or a combination of both these factors. Furthermore, I will exploit my role as lead for the Radio Galaxy Zoo project on spiral DRAGNs to find more of these sources. To-date there have been only four spiral DRAGNs detected. Increasing the sample size is imperative for testing the hypotheses that will be formed in the above two science goals, and enable statistically significant conclusions to be drawn.", "To": ["2018-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["660432"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER", "THE UNIVERSITY OF MANCHESTER", "KATHOLIEKE UNIVERSITEIT LEUVEN"], "EU_Contribution": ["EUR 1 584 202,30"], "Project_Title": ["Radical Solutions for Hysteresis in Single-Molecule Magnets"], "Total_Cost": ["EUR 1 584 202,30"], "Country": ["United Kingdom", "United Kingdom", "Belgium"], "Project_ACR": ["RadMag"], "Technology_Description": "Single-molecule magnets (SMMs) display magnetic hysteresis that is molecular in origin, and these materials have huge potential to be developed as nano-scale devices. The big challenge is to create SMMs that function without the need for liquid-helium cooling.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["646740"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["UNIVERSITAET GRAZ", "SOUTH-WEST UNIVERSITY NEOFIT RILSKI", "DIETHNES PANEPISTIMIO ELLADOS", "Institute of National History Skopje", "BILKENT UNIVERSITESI VAKIF", "UNIVERSITATEA DE STAT DIN MOLDOVA", "INSTITUTUL DE ISTORIE NICOLAE IORGA", "ODESSA NATIONAL I.I. MECHNIKOV UNIVERSITY", "SHOTA RUSTAVELI STATE UNIVERSITY", "FEDERAL STATE BUDGETARY EDUCATIONALINSTITUTION OF HIGHER EDUCATION PYATIGORSK STATE UNIVERSITY", "\"\"\"Matenadaran\"\" M.Mashtots Institute of Ancient Manuscripts\"", "AZERBAYCAN MILLI ELMLER AKADEMIYASININ ARXEOLOGIYA VE ETNOGRAFIYA INSTITUTU"], "EU_Contribution": ["EUR 1 665 000"], "Project_Title": ["Knowledge Exchange and Academic Cultures in the Humanities: Europe and the Black Sea Region, late 18th \u2013 21st Centuries"], "Total_Cost": ["EUR 1 665 000"], "Country": ["Austria", "Bulgaria", "Greece", "Former Yugoslav Republic of Macedonia", "Turkey", "Moldova", "Romania", "Ukraine", "Georgia", "Russia", "Armenia", "Azerbaijan"], "Project_ACR": ["KEAC-BSR"], "Technology_Description": "When the transfer of modern sciences to and the study of the Black Sea Region (BSR) began in the late 18. century, this area was not yet considered part of Europe. The proposed inter/multidisciplinary research and exchange project\u2019s title refers to that fact. Knowledge and science exchange between Europe and the BSR intensified in the course of the 19th and early 20th century and was interrupted when as result of WWI/WWII a significant part of the BSR was integrated into the Soviet Union\u2019s orbit. The BSR disappeared behind the Iron Curtain and the academic cultures of West and East drifted apart. The previous 25 years have witnessed strengthening ties between BSR countries and between the BSR and the rest of Europe as well as globalisation of knowledge and scientific exchange. The integration of the BSR into the European Research Area (ERA) is on the way but not yet completed. The proposed project provides excellent opportunities to critically reflect the sketched processes and to look into future.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations"], "From": ["2017-01-01"], "Project_ID": ["734645"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER", "THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 149 924"], "Project_Title": ["A compact radioisotope dating device for rapid sample analysis"], "Total_Cost": ["EUR 149 924"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["CompactDating"], "Technology_Description": "The FNPMLS project (ERC n.648381) has successfully demonstrated that resonance ionization spectroscopy can be performed efficiently and with high resolution on an accelerated beam (CRIS). This novel and versatile methodology has been used to measure exotic nuclei down to rates of less than 20 atoms/second. In order to achieve these results the CRIS method has had to efficiently remove interference isotopes that would otherwise saturate the detectors. The key advantages of the method are its high selectivity, interference suppression and compact size. In principle it can be combined with mass spectrometry techniques such as ICP-MS and IRMS to enhance their respective sensitivity by more than three orders of magnitude in a compact table top device. This would have applications in the industries that utilize radioisotope detection for molecular labelling and dating. We believe that our methodology has the potential to significantly reduce the costs associated detecting isotopes such as 14C. In this project we will define and develop a commercialization strategy and effective route to market as well as produce a well defined IP position. A prototype device with autosampling capabilities will be constructed and used for benchmarking and validation tests that will further inform the marketing strategy. The final deliverables of this project will be a package consisting of a working prototype that demonstrates the ability to rapidly analyse biological samples and a commercialization strategy that has a clearly defined route to market and IP position.", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["768258"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER", "THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 2 337 548"], "Project_Title": ["Biocatalytic Amine Synthesis via Hydrogen Borrowing"], "Total_Cost": ["EUR 2 337 548"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["BIO-H-BORROW"], "Technology_Description": "Amine containing compounds are ubiquitous in everyday life and find applications ranging from polymers to pharmaceuticals. The vast majority of amines are synthetic and manufactured on large scale which creates waste as well as requiring high temperatures and pressures. The increasing availability of biocatalysts, together with an understanding of how they can be used in organic synthesis (biocatalytic retrosynthesis), has stimulated chemists to consider new ways of making target molecules. In this context, the iterative construction of C-N bonds via biocatalytic hydrogen borrowing represents a powerful and unexplored way to synthesise a wide range of target amine molecules in an efficient manner. Hydrogen borrowing involves telescoping redox neutral reactions together using only catalytic amounts of hydrogen.", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["742987"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 212 194,80"], "Project_Title": ["Why do We Need a Realist Constitutional Theory to Study the Politics of Constitutional Change in the Middle East?"], "Total_Cost": ["EUR 212 194,80"], "Country": ["Denmark"], "Project_ACR": ["Realist"], "Technology_Description": "This research programme aims to make contribution to comparative political and legal theory by studying the recent constitutional transformation in the Middle East in at least three grounds. First, in arguing that a constitution always comes into being as a result of a historical process and a decision (will), such historical-sociological context and power relations behind the creation of constitutions can be grappled with best by a realist political and legal theory. A realist approach sees constitutions as the ultimate battleground for the groups competing for power to constitute the foundational norms and values of society. Second, if a constitution is created by a decision, there is always an agency behind that decision that executes its will power. In democratic theory such agency is being defined as the people, but the people cannot manifest its will without a representative (e.g. a class, constituent assemblies, or conventions). To this end, a realist approach carefully examines the agency of Islamic political parties so as to understand the peculiarity of the constitution-making in the Middle-East. Peculiarity here is that the recent revolutions brought Islamic parties to government, but this has only helped destabilizing the new, or present, constitutions and weakening the hope for accommodation of Islamist groups in a liberal democratic and secular constitution. Third, a comparative realist approach examines both the Western and Islamic sources of legitimacy so as to have a nuanced understanding of the contemporary crises of legitimacy which now dominates the entire region. Such comparative study is necessary because the Western (secular) concepts and institutions such as constitution, freedom of association, competitive elections, parliamentarianism and liberal rights have already moved from the Western context to other regions, setting the agenda of political discourse.", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["746390"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA", "THE UNIVERSITY OF EXETER", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "UNIVERSITEIT TWENTE", "FONDAZIONE EDMUND MACH", "AEROVISION BV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "VLAAMSE INSTELLING VOOR TECHNOLOGISCH ONDERZOEK N.V.", "FORSCHUNGSZENTRUM JULICH GMBH", "QUESTUAV LTD"], "EU_Contribution": ["EUR 3 062 364,12"], "Project_Title": ["Training on Remote Sensing for Ecosystem modElling"], "Total_Cost": ["EUR 3 062 364,12"], "Country": ["Italy", "United Kingdom", "Spain", "Netherlands", "Italy", "Netherlands", "Germany", "Belgium", "Germany", "United Kingdom"], "Project_ACR": ["TRuStEE"], "Technology_Description": "Understanding and predicting ecosystem functions remains a major challenge in evaluating ecosystem services and biophysical controls on biosphere-atmosphere interactions, as current dynamic vegetation models are still not capable of grasping the spatial and temporal variability in ecosystem processes. Remote sensing (RS) data at a range of scales from proximal observations to global extent sampling can detect essential changes in plant traits (PTs), biodiversity and ecosystem functioning, providing a method for scaling-up. However there are still methodological and technical constraints that hamper a systematic incorporation of RS in ecosystem models, including scalability and multi-source data integration issues. TRuStEE will train a new generation of scientists with complementary and interdisciplinary skills in ecosystem modelling, plant physiology, RS technologies and big data analysis, addressing the specific objectives: 1) to identify essential biodiversity variables (EBVs) and the link with PTs and ecosystem functional properties (EFPs), inferable from RS, 2) to investigate a completely new avenue for assessing vegetation photosynthetic efficiency from RS measurements of canopy fluorescence, 3) to assimilate diverse RS data streams with varying spatial and temporal resolution in dynamic ecosystem models and 4) to exploit new satellite missions (e.g. ESA-FLEX, ESA-Sentinels, NASA-GEDI) and EO products for the upscaling of PTs, EBVs and EFPs. The early stage researchers (ESRs) involved will strongly benefit from the network of internationally recognized scientists and private companies with relevant expertise in these topics. The cooperation program proposed will link academic and non-academic participants to allow the circulation of ESRs giving them the opportunity to become new research and innovation leaders in the most cutting edge sophisticated technologies in the field, increasing their employability in both academic and private sectors.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-10-01"], "Project_ID": ["721995"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Post-transition metal chalcogenides: 2D nanoelectronics and photonics"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["PTMCnano"], "Technology_Description": "Post-transition metal chalcogenides (PTMCs) such as InSe or GaSe are members of the rapidly expanding family of two-dimensional (2D) materials. Unlike graphene, they possess an electronic band gap, enabling electrostatic confinement of electrons by using local gate electrodes, and therefore the creation of quantum dots (QD). QDs can be employed as the bases for spin qubits, possible building blocks of solid state quantum computers. Recent results of the host suggest that PTMCs may surpass other gapped 2D crystals in electron mobility, making possible the fabrication of QDs of exceptional quality. Moreover, their near-direct band gap enables their use in photovoltaic, photodetection and LED applications, and opens the way for interfacing photons with spin qubits, essential in long-distance communication between quantum computers. The proposed objectives entail the realization of electrostatic confinement to study state of the art PTMC QDs, and testing their viability as spin qubits via magnetoconductance measurements, and also the investigation of the electro-optical response of 2D heterostructures to address single photon to electron conversion in QDs, and possibilities towards application in communication, sensing and solar power conversion.", "To": ["2019-09-17, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-18"], "Project_ID": ["751883"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER", "THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 1 965 170,98"], "Project_Title": ["Next Steps in Cosmology with CMB Spectral Distortions"], "Total_Cost": ["EUR 1 965 170,98"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["CMBSPEC"], "Technology_Description": "The average spectrum of the cosmic microwave background (CMB) has long been known to be extremely close to a perfect blackbody. Yet, several processes, standard and non-standard, exist that may cause deviations from a blackbody spectrum, commonly referred to as CMB spectral distortions. Classical distortion shapes are known as Compton-y and chemical potential (\u00b5-type) distortions; however, recently it has been shown that more general distortions can be created at redshifts 10^4 < z < 3\u00d710^5. This makes spectral distortions a unique and powerful probe of different early-universe processes. The immense potential of CMB spectral distortion measurements and their synergies with upcoming CMB anisotropy studies (Litebird, COrE+, Stage-IV CMB) has identified them as an important future target, with several innovative experimental concepts (e.g., PIXIE, APSERa) being actively discussed by the cosmology community.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["725456"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 269 857,80"], "Project_Title": ["Stimuli-Responsive Two-Dimensional Materials for Renewable Energy"], "Total_Cost": ["EUR 269 857,80"], "Country": ["United Kingdom"], "Project_ACR": ["2DMAT4ENERGY"], "Technology_Description": "I will engineer van der Waals (vdW) heterostructures of two-dimensional (2D) materials with tuneable electrochemical response for exploitation in renewable energy applications. These heterostructures, which are constructed by stacking 2D crystals on top of each other, have been attracting increasing attention in solid-state physics, optoelectronics, and photonics but their full potential in electrochemical applications such as energy storage, conversion, and sensing remains completely unexploited. I will control their electrochemical response by external stimuli including electric field, strain, and illumination. In order to succeed, I will first develop a solid understanding of the unexplored key electrochemical properties of 2D materials and their dependence on these stimuli. I will fully exploit my recent experience in 2D materials\u2019 research and the access to the world-class nanofabrication and characterisation facilities and scientific expertise at Cornell University, the University of Manchester, and National Physical Laboratory.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["746685"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER", "THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 2 498 645"], "Project_Title": ["Nanopores for New Molecular Nitrogen Chemistry"], "Total_Cost": ["EUR 2 498 645"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["NANOCHEM"], "Technology_Description": "We will study the adsorption, binding, transport and reactivity of N-containing substrates within the nanopores of functionalized and doped metal-organic framework (MOF) materials. A range of important target molecules (e.g., NH3, N2H4, N2O, NO, NO2 and N2O4) will be studied in this project, which aims to re-define the molecular chemistry for these energetic N-compounds in confined space, and to develop selective catalytic reduction (SCR) of NOx in the presence of NH3, urea and hydrocarbons. The PI has extensive experience in the field of coordination chemistry and hybrid materials, and seeks to change research direction to develop new gas phase catalysts and to gain fundamental understanding of molecular interactions, properties and function of specific energy, environmentally-related substrates within MOFs. Research objectives include the:", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["742401"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Non-Thermal PLasma Enabled cAtalysis-Separation system for UpgRading biogasto mEthane-NTPleasure"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["NTPleasure"], "Technology_Description": "Biogas (CO2, 15~60 vol.%, CH4, 40~75 vo.l%) is produced by the anaerobic digestion of organic wastes such as sewage, food wastes and landfill, which can produce biomethane as the transport fuel. Therefore, extensive efforts have been dedicated for the separation of CO2 from biogas to enrich CH4 present. In addition, the further utilization of separated CO2 (e.g. CO2 to methanol or CH4) is also a challenge for directing its carbon cycle and hence reducing the current greenhouse gas emissions. In this project, an integrated separation-nonthermal plasma (NTP)-catalyst system will be developed to enable the full utilization and valorisation of biogas. The system will be based on selective capture of CO2 from the biogas stream using ultra-thin SAPO-34 zeolite membranes (~1 \u03bcm thickness) and the subsequent NTP-assisted catalytic CO2 methanation on Ni- and/or Co-based catalysts supported on 5A zeolite membrane (~3 \u03bcm thickness). The integrated design combining CO2 capture with CO2 methanation at ambient temperature will be an excellent candidate for further exploitation in the industrial scale biogas upgrade process. This project will also use transient kinetics and advanced in-situ characterization methods to understand the reaction mechanism and nature of the active site, including steady-state isotope kinetic analysis, short-time-on-stream diffuse reflectance infra spectroscopy and near ambient pressure X-ray photoelectron spectroscopy, etc.", "To": ["2020-01-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-15"], "Project_ID": ["748196"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Gender gap in students\u2019 achievement: the role of social, economic, geographical and cultural variables"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["GE.GAP-EDU"], "Technology_Description": "The study of academic achievement as function of \u2018gender\u2019 has received an increasing interest. Nevertheless, this topic seems still topical, at least for the following reasons: until now, some explanatory variables have been picked out but, probably, further unexplored factors exist; 2) the relationship between those factors has not been disclosed yet, i.e. it is not clear if interaction effects between them exist. In particular, the sectorial literature has investigated gender-related stereotypes\u2019 effects on academic achievement but it has not studied possible interactions between stereotypes and the other variables frequently used to study students\u2019 performance; 3) the inter-national comparison is undoubtedly an adequate method to deepen the study of gender-based gap. Nevertheless, the big international research institutes use national data, and it is clear that, when we use big data (such as national ones), almost automatically, some dangerous compensations occur, leading data to a false medium value. Our approach based also on the intra-national comparison is able to avoid those compensations. In fact, the comparisons between macro-geographical clusters produce better data, i.e. data that reproduce the reality more realistically, with three main consequences: 1) to improve the probability of picking out factors that can explain academic achievement depend on gender variable; 2) to guide local (inter-/national) policies; 3) to produce new data that can be used in future researches. Moreover, also the cross-national comparison (between macro-geographical areas within different Countries) could produce new important data because, through it, some possible \u201cregularities\u201d across different Countries can be disclosed, such as, for example, the same interaction effect between stereotypes and social-economic variables, etc. It could be an interesting headway in the field because it could indicate results that are true independently from specific context.", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["752874"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Russian Nationalism and the Ukraine Crisis: The Impact of Nationalist Actors on Russian Foreign Policy"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["RUSNAT"], "Technology_Description": "As nationalist sentiments are on the rise among broader Russian public, nationalist actors may exercise a more significant role in Russian politics. The main objectives of RUSNAT are: 1) to analyse the impact of the events in Ukraine on representative organizations of grassroots nationalism in Russia; 2)to analyse the ideologies of Russian nationalists and the Russian government with respect to the events in Ukraine;3)to develop a theoretical and conceptual framework appropriate for the analysis of the impact of Russian nationalists\u2019 activism on the government\u2019s foreign policy towards neighbouring countries with Russian populations, e.g. the Baltic states. They will be achieved through Discourse Analysis, Critical Discourse Analysis and close reading of primary sources generated by nationalists and representatives of Russian foreign policy from 2014 to 2016. I will construct a database covering nationalist frames, elite discourse (civic, ethnic, imperialist), and nationalist disruptive events. The influence of nationalists will be considered as positive if a nationalist frame is adopted by the elite discourse at a later date and if elite discourse changes after sudden disruption events organized by the nationalists. This research offers insight into the influence of nationalist actors on policy-making in post-communist societies; it helps assess the extent to which in non-democratic contexts foreign policy is driven by nationalist ideals in its initial phases; it contributes to our understanding of Russia\u2019s relations with neighbouring countries with Russian populations and with the European Union as a geostrategic partner with whom Russia shares this neighbourhood; and, it will help us understand whether the growing influence of nationalist actors directly encourages the radicalization of Russian policies in near abroad. This is relevant for the design and implementation of EU policies regarding its Eastern neighbourhood and strategic partnership with Russia.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["752387"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["The use of mass spectrometry and optical methods to determine the influence of cofactors on the structure and stability of proteins"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["PHOTO_IMS"], "Technology_Description": "This fellowship will use novel instrumentation to define the role of cofactors on the structure and stability of proteins. We have recently adapted a commercially available Synapt ion mobility mass spectrometer to allow it to perform optical measurements on conformer and mass selected ions, in collaboration with Waters Corp. The heart of this instrument is the ion mobility cell, IM-MS measurements are possible in this instrument, as for any Synapt mass spectrometer, but uniquely we are able to trap ions that have been conformer selected, to allow optical measurements in a so called \u2018photo SRIG\u2019 (stacked ring ion guide). Such optical measurements can take several forms, including IR-spectroscopy, UV/Vis-spectroscopy, which will provide structural analysis of co-factors and coenzymes, photo-dissociation to sequence the proteins as well as fluorescence to probe global conformations.", "To": ["2020-02-29, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["750642"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 496 607,50"], "Project_Title": ["Metrology of Carbohydrates for Enabling European Bioindustries"], "Total_Cost": ["EUR 496 607,50"], "Country": ["United Kingdom"], "Project_ACR": ["CARBOMET"], "Technology_Description": "CarboMet will foster and drive collaboration, cross-fertilisation and communication among stakeholders to facilitate a uniform approach to the metrology and/or measurement of carbohydrates for exploitation in biopharmaceuticals, diagnosis of disease and precision medicine, food and personal care and sustainable material BioIndustries. This will be achieved through a consolidated approach towards the modification of key emerging technologies or identification of radically new technologies currently unforeseen by technology roadmaps.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-02-2016 - FET-Open Coordination and Support Actions"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["737395"], "Call_for_Proposal": ["H2020-FETOPEN-2-2016"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Molecular Robotics for Synthesis and Catalysis"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["RoboCat"], "Technology_Description": "The aim of this project is to design, synthesize and investigate the operation of synthetic molecular machines capable of performing sophisticated tasks in chemical synthesis. The molecular machines are inspired by biological systems, where substrates are shuttled between different enzymatic sites, undergoing chemical transformations at each step. Control of substrate position allows for reactions to occur in a specific sequence, with the molecular machine dictating the selectivity of each successive chemical reaction. The project both seeks to optimize the structure of the molecular machines for use as a synthetic platform and demonstrate their usefulness for synthesis and catalysis in model reactions. The successful demonstration of this concept would mark the beginning of a fundamentally new approach for the construction of molecules.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["746993"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER", "THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 1 755 278,75"], "Project_Title": ["Illuminating Atomic Scale Processes in Liquids and Gases"], "Total_Cost": ["EUR 1 755 278,75"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["EvoluTEM"], "Technology_Description": "EvoluTEM: Illuminating Atomic Scale Processes in Liquids and Gases", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["715502"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER", "THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 2 926 425"], "Project_Title": ["Correlative tomography"], "Total_Cost": ["EUR 2 926 425"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["CORREL-CT"], "Technology_Description": "Proposal summary (half page)", "To": ["2021-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-11-01"], "Project_ID": ["695638"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER", "THE UNIVERSITY OF MANCHESTER", "KAROLINSKA INSTITUTET"], "EU_Contribution": ["EUR 1 999 337,50"], "Project_Title": ["Children and Adolescents with PaRental mental Illness: Understanding the \u2018who\u2019 and \u2018how\u2019 of targeting interventions"], "Total_Cost": ["EUR 1 999 337,50"], "Country": ["United Kingdom", "United Kingdom", "Sweden"], "Project_ACR": ["CAPRI"], "Technology_Description": "At least 10% of mothers and 5% of fathers have a mental illness. Family, educational and social lives of children and adolescents with parental mental illness (CAPRI) are disrupted by deprivation and repeated hospitalisation. This is an urgent political and public health concern. The Child and Adolescent Mental Health in Europe (CAMHEE) report urges us \u2018to acknowledge and attend to the needs of children and families with parental mental health... \u2019 recommending better information on CAPRI risks and resilience so interventions can target those at highest risk. This groundbreaking interdisciplinary programme exploits my unique combination of expertise in epidemiology and neuroscience to deliver on CAMHEE objectives for CAPRI. ", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["682741"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER", "THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 1 995 655,76"], "Project_Title": ["Fundamental Physics Using Black Widow, Redback and Transitional Pulsar Binaries"], "Total_Cost": ["EUR 1 995 655,76"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["Spiders"], "Technology_Description": "I will use an innovative coupled approach to facilitate a paradigm shift in the use of neutron stars as a probe of high energy physics. The compactness, rapid rotation and large magnetic fields of neutron stars make them, along with black holes, the most extreme objects found in our Universe. Neutron stars are therefore formidable laboratories to study fundamental physics, as they allow us to probe regimes simply unavailable to Earth-based experiments. However, in spite of their potential utility, there are still a number of important outstanding questions in this field. Key amongst these are: What is the neutron star equation of state? How do neutron stars become the fastest rotating stellar objects in the Universe? How do millisecond pulsars affect their environment? Answering these questions has a broad multi-disciplinary impact, far beyond the field of neutron star research alone; however, at present our ability to answer these questions is limited by cherry picking individual objects for study. In this proposal I describe how I will move away from the biases inherent in the idiosyncratic nature of particular sources to a comprehensive population analysis, and specifically, how I will use a particular class of neutron star systems, known as \u201cspider binaries\u201d, to discover the most massive and the fastest spinning neutron stars that exist. Such extreme cases are of crucial importance for constraining the neutron star equation of state and thus determining the boundary for stellar mass black hole formation. This knowledge in turn can tell us about possible phase transitions of matter at high densities and provide observable quantities that can then be tested against Earth-based experiments, feeding back into high energy physics theories. I will achieve these goals through a transformational observational approach to finding new spider systems and drawing on innovative techniques from other fields to improve parameter estimation.", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["715051"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["AKZO NOBEL CAR REFINISHES BV", "THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 1 276 871,40"], "Project_Title": ["Sustainable Organic Coatings for Corrosion Protection"], "Total_Cost": ["EUR 1 276 871,40"], "Country": ["Netherlands", "United Kingdom"], "Project_ACR": ["SUSTICOAT"], "Technology_Description": "BACKGROUND / NEED:", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["Netherlands"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["721451"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER", "THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 149 817"], "Project_Title": ["An ultra compact greenhouse gas remote sensing system for ranges between 500 and 2000 m"], "Total_Cost": ["EUR 149 817"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["CarbSens"], "Technology_Description": "The CO2Volc project (ERC n.279802) has produced an active remote sensing instrument based on the differential absorption LIDAR principle, called CO2DIAL. It is designed to measure column averaged CO2 concentrations for path lengths between 500 and 2000 m. A key advantage over other open-path techniques is that no retroreflector or separate active source is required for fence-line monitoring. It therefore fills a key operational gap in CO2 sensing technologies. In addition, through a laser replacement, the instrument can be used to measure also CH4, allowing both main carbon gas species to be quantified, and producing the name of this project, CarbSens. An affordable greenhouse gas (GHG) sensing platform with spatial coverage of 2000 m that fits into a backpack, can be mounted on an aircraft, car, mast or even a drone would have a wide variety of commercially attractive applications. These include efficient monitoring of CO2 leakage from CO2 storage sites or urban traffic, quantification of fugitive CH4 upon hydraulic fracturing (fracking), CH4 leakage from pipelines or biogas tanks, or refining regional GHG budgets for improved climate modeling. A system with the features of the CO2DIAL is not commercially available. We believe that our technology has the potential to create a new market for affordable, man-portable remote gas sensors, and carbon quantification services. In the initial project phase we will define an adequate commercialization strategy, focusing on user groups in the hydrocarbon and carbon sequestration industries. A commercial prototype will then be derived from the CO2DIAL. A focus will be to make the system affordable (<40 k\u20ac) and even more compact and lightweight (< 10 kg) to arrive at an instrument that is suitable for a large group of users. The final goal of the proposal is to produce a portfolio consisting of a working commercial prototype and a marketing strategy, including either secured licensing or the initiation of a spin-out company.", "To": ["2018-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["727626"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Structural Engineering of 2D Atomic Planes towards Task-Specific, Freestanding Superstructures through Combined Physical-Chemical Pathway"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["CHEPHYTSSU"], "Technology_Description": "The research on 2D nanomaterials has boomed since the discovery of graphene by professors Geim and Novoselov in 2004. After a decade of steady development, the available library of 2D crystals is highly rich including graphene derivatives, hexagonal boron nitride, many chalcogenides and various oxides. However, the technological advances and urgent environmental and sustainable energy issues such as CO2 capture and separation, energy storage and conversion (photovoltatic system, supercapacitor etc) call for advanced materials with not only properties of individual layers but also new functionalities. Particularly, researches on superstructures with unique properties such as amphiphilicity still remain blank. Physically, it is now possible to create such hybrid superstructures by placing different 2D crystals on top of each other in a designed sequence; while engineering the 2D units through a chemical way endows a high flexibility in surface chemistry tailoring and increase the mechanical stability due to the strongly bonded interface. Taking these into consideration, here we propose a combined chemical-physical pathway to engineer task-specific, mechanically freestanding superstructures based on 2D atomic planes in a simple and scalable manner. Three new material concepts are proposed including amphiphilic superstructure (hydrophilic outer layer and hydrophobic inner layer), gas selective superstructure (CO2-phililc outer layer and gas shape selective inner layer) and flexible superstructure with outer layer functionalized with metal oxide nanoparticles confined in ordered mesopores and inner conductive graphene. The obtained superstructures with these structural features will be oriented environmental and sustainable energy issues such as CO2 capture and separation, water purification and flexible electrode. Finally, structure-performance relationship will be unraveled fundamentally.", "To": ["2018-07-24, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-07-25"], "Project_ID": ["707096"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER", "THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 149 662"], "Project_Title": ["Enhancing OLED device performance using Fused Borylated Materials"], "Total_Cost": ["EUR 149 662"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["B-Brighter"], "Technology_Description": "Organic Light Emitting Diodes (OLEDs) are attractive for use in high efficiency illumination and flexible displays. The current state of the art OLED materials use Ir or Pt based phosphorescent materials, which whilst achieving impressive efficiencies have significant cost, and supply issues associated with rare precious metals. Metal free OLEDs are preferable based on low relative cost and ease of fabrication but to date have not been competitive with Ir / Pt based OLEDs. This is because metal free OLEDs have relatively low efficiency as light emission is due to fluorescence inherently limiting the systems to 25% of excitons. A new approach has now enabled metal free OLEDs to break this efficiency barrier \u2013 using the phenomena of thermally activated delayed fluorescence (TADF). However, TADF emitters in the deep red / Near infra red (NIR) region of the spectra (desired for applications in optical communications, night vision devices and sensors) are rare and currently sub-optimal.", "To": ["2018-01-31, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2015 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-08-01"], "Project_ID": ["713368"], "Call_for_Proposal": ["ERC-2015-PoC"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER", "THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 3 488 955,91"], "Project_Title": ["Discovering Fast Transients and Pulsars with MeerKAT for Cosmology and to Test the Laws of Gravity"], "Total_Cost": ["EUR 3 488 955,91"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["MeerTRAP"], "Technology_Description": "Short duration bursts of cosmic radio emission provide us with a potent tool for studying the extremes of physics. In the form of periodic pulses from pulsars they can be used as precision instruments to test theories of gravity, understand the emission processes and the equation of state of ultra-dense matter. In the form of transient bursts we can use them to study the physics governing explosive events such as gamma-ray bursts, merging neutron stars, annihilating black holes or hitherto unknown phenomena. Observing how these bursts are affected by their passage through the distant Universe allows us to probe its physical state. To harness the combined power of periodic and bursting radio sources to explore physics beyond that possible in a terrestrial laboratory I propose MeerTRAP: Meer (more) TRAnsients and Pulsars, a project to continuously use the MeerKAT telescope to search the radio sky for pulsars and fast transients and to rapidly and accurately locate them. Utilising the excellent sensitivity and sky coverage of MeerTRAP my team will discover many rare and scientifically important pulsar types: relativistic binaries, intermittent emitters, transitioning systems. Current radio telescopes have only explored the tip of the transients \"iceberg\" and MeerTRAP will transform our knowledge of these manifestations of extreme physics. It will detect hundreds of new bursts, which will all be well localised, allowing us to identify hosts and distances, greatly enhancing their use as cosmological probes. Localisation also enables measurement of their true fluxes, polarisation and spectral indices which are all crucial to identify their origin. To achieve this we will design, implement and exploit state-of-the-art hardware and software. We will also use the MeerLICHT optical telescope, which will track MeerKAT, to give us a crucial glimpse of the optical sky immediately before and after any radio transient to further constrain their origin and the associated physics.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["694745"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER", "THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 2 494 328,75"], "Project_Title": ["Prenylated-flavins: Application and Biochemistry"], "Total_Cost": ["EUR 2 494 328,75"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["pre-FAB"], "Technology_Description": "Our group has recently discovered a new type of cofactor: a prenylated-flavin that has azomethine ylide properties. This cofactor is an integral part of the widespread ubiD/ubiX system. The latter is implicated in the non-oxidative reversible decarboxylation of aromatic substrates, and plays a pivotal role in bacterial ubiquinone biosynthesis or microbial biodegradation of aromatic compounds. We established UbiX acts as a novel flavin prenyltransferase, linking a dimethylallyl moiety to the flavin N5 and C6 atoms. Formation of the holo-UbiD enzyme involves oxidative maturation of the new cofactor, creating the novel azomethine ylide moiety. The dipolarophile substrate binds directly above the azomethine ylide group, and our data strongly suggests 1,3-dipolar cycloaddition chemistry supports reversible decarboxylation in these enzymes. While 1,3-dipolar cycloaddition is commonly used in organic chemistry, this presents the first example of an enzymatic 1,3-dipolar cycloaddition reaction. Our model for UbiD catalysis hints at new routes in alkene hydrocarbon production or aryl (de)carboxylation. ", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["695013"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER", "THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 1 997 219"], "Project_Title": ["Delivering on the Promise of Measuring Dark Energy from Cosmic Lensing"], "Total_Cost": ["EUR 1 997 219"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["COSMIC LENS"], "Technology_Description": "The apparent gravitational distortion of distant galaxies, \u2018cosmic lensing\u2019, allows us to map dark matter and hence unveil the nature of the mysterious dark energy. I will develop novel approaches to cosmic lensing and use these to place constraints on dark energy using the Dark Energy Survey (DES). Themes 1 and 2 address key systematic effects crucial for the extraction of cosmology in theme 3. Theme 1: The lensing community has spent two decades trying to find the perfect galaxy shape measurement method. We will take a unique approach by translating a technique common in particle physics and the CMB to lensing: we will simulate images matched to observed galaxy positions and shapes, and vary lensing to accurately calibrate shapes. We will make the code public and use it to produce the final public DES shear catalogues. Theme 2: We will exploit my innovative and successful program of coordinated international challenges from shear measurement and apply it to mitigating galaxy intrinsic alignments (IA). I have shown that knowledge of IAs is essential for leveraging the potential of cosmic lensing for cosmology and described a mitigation method, but this needs to be tested on simulations. I will coordinate international IA simulation efforts and identify the optimum method for removing intrinsic alignments and apply it to the DES data. Theme 3: We have developed a skeleton software framework for cosmology, CosmoSIS. We will write modules for cosmology from imaging data incorporating the main systematic effects, and use CosmoSIS to produce the final constraints on cosmology from DES lensing. We will incorporate constraints on sterile neutrinos from particle physics for the first time. If the current tensions between cosmic lensing the CMB are confirmed by this work we will have discovered the need for new physics. Furthermore, the work in this proposal will place us in prime position to exploit the main cosmology surveys of the next decade (LSST, Euclid, WFIRST).", "To": ["2021-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["681431"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Measurement of charm matter-antimatter asymmetries"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["CharmingAntimatter"], "Technology_Description": "Flavour physics, and the study of antimatter in particular, is one of the most exciting fields at the frontier of fundamental physics research. It is driven by the question of what happened to the antimatter after the Big Bang and is a recognized long-term priority as part of the CERN European strategy for particle physics. Nature provides particles that contain both matter and antimatter quarks as ideal laboratories for the discovery of matter-antimatter asymmetries (CP violation). This proposal will focus on the least explored of these particles, charm mesons; CP violation discoveries in strange and beauty mesons have already led to Nobel Prizes.", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["704733"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 233 811"], "Project_Title": ["The invisible city. Mapuche mapping of Santiago de Chile."], "Total_Cost": ["EUR 233 811"], "Country": ["United Kingdom"], "Project_ACR": ["MAPS-URBE"], "Technology_Description": "The proposed research explores experiences of urban space among young indigenous Mapuche living in Santiago de Chile, in order to make visible indigenous subjects whose daily lives, collective concerns and social circumstances are often relegated to the margins of policy making and public interest. It seeks to research the impact of displacement and social exclusion on indigenous youth, as well as offer a means of intervention. The project will identify a set of mutually negotiated research aims alongside young Mapuche, developing a series of collaborative and participatory methods, including mapping, video and exhibition making, to offer a better understanding of indigenous experiences of the city as a kind of \u201cin betweeness\u201d - as expressed by the term Mapurbe, from mapu (earth) and urbe (city) - used to symbolize the on-going negotiation of marginality and displacement from the ancestral territory. The outcome of the collaborative research will be used to address the relationship with non-Mapuche citizens through two exhibitions (in Chile and Europe), offering young Mapuche an opportunity to make an active intervention into public discourse. The proposed research thus aims to apply theoretical knowledge, collaborative methods and modes of representation to issues of critical social interest in ways that are directly applicable to other context within Latin America and across Europe. The necessary training-through-research will be at the Instituto de Estudios Urbanos y Territoriales - Pontificia Universidad Cat\u00f3lica (Chile), and at the Granada Centre for Visual Anthropology - University of Manchester (UK). This will provide the researcher with theoretical and technical competencies in Urban Studies and Visual Anthropology. The proposed research will contribute to the strengthening of European networking at an interdisciplinary and inter-continental level, building an international dialogue that will have positive and practical impacts on the European Research Area.", "To": ["2020-02-29, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-03-01"], "Project_ID": ["707537"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Visible Light-Mediated Synthesis of Nitrogen-Centered Radicals: New Reactivity via Photoredox Catalysis and Electron-Transfer Complexes"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["NCR"], "Technology_Description": "Nitrogen-containing molecules are among the most important class of compounds due to their relevance as medicines, agrochemicals, organic materials and dyes. Nitrogen-centered-radicals are a class of very versatile synthetic intermediates with great potential in the synthesis of N-containing molecules. However, to date, difficulties associated to their generation have severely limited their use and exploitation. Here we propose the development of two conceptually novel and general ways to prepare Nitrogen-centered radicals using visible light as sustainable and inexpensive source of energy. These processes will capitalize on recent developments in the host group that has disclosed the use of easy-to-make aryl oximes for the organocatalytic generation of iminyl radicals. This proposal seeks to substantially expand this visible light chemistry through the development of methods for the generation and use of any known Nitrogen-centered radical. The power of this approach will be demonstrated by the short synthesis of the complex molecule legionaminic acid, responsible for the spread of hospital-acquired infections. Furthermore, these methods will be integrated with other reaction platforms that, taking advantage of visible light as source of energy, will engage the Nitrogen-centered radical in new reactivity modes, to allow novel and powerful multicomponent reactions.", "To": ["2019-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-02-01"], "Project_ID": ["703238"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Transition Friction in the Ecuadorian Amazon: A Green Economy Ethnography"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["TRANSITION-FRICTION"], "Technology_Description": "The dominant framing of humanity\u2019s current predicament emphasizes \u2018planetary limits\u2019 and impending environmental collapse, with \u2018green economy\u2019 strategies as a necessary response. Initiatives for transitions to \u2018green\u2019 production and consumption patterns are emerging and multiplying, at different scales and all over the world. The visions of \u2018sustainability\u2019 underpinning these initiatives are diverse, and their heterogeneous socio-ecological effects raise urgent questions of justice. With a focus on the power dynamics and inequalities of green transition initiatives, TRANSITION-FRICTION will cross-fertilise three literatures \u2013 political ecology, transition studies and ethnographies of global connections.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["707017"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Bimetallic catalytic arylation of simple arenes"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["BiMetArylation"], "Technology_Description": "The development of new methodologies for the preparation of biologically and industrially interesting compounds remains one of the fundamental challenges in chemistry. Aryl-aryl bond formation is one of the most important tools in modern organic synthesis. These biaryl motifs are very often found in pharmaceutical, agrochemicals, organic materials and natural products. Given the abundance of C\u2013H bonds in organic molecules, the selective activation and use of these bonds in controlled synthetically useful transformations is an immensely important topic. In this context, direct C\u2013H arylation has emerged as a powerful methodology for the synthesis of biaryls. However, in most methodologies described so far, the arene substrate must fulfil certain requirements such as containing strong electron-withdrawing or electron-donating groups, or bearing special directing groups. Substrates lacking this feature either are unreactive or must be used in large excess (often as solvents). The coupling of \u2018simple arenes\u2019, which are not considered as pi-electron-deficient or -rich remains challenging.", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["702177"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Olfactory processing of repellent and attractive stimuli in the brain of Drosophila"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["OPRAS"], "Technology_Description": "Mosquito-borne diseases present one of the greatest threats to human health. Mosquitoes find humans by detecting human body odour and CO2 with their olfactory system. This project addresses the fundamental and still unresolved question of how odorant valence is coded in the brain and why odorants that are attractive (positive valence) at low concentrations, switch to being repulsive (negative valence) at high concentrations. This phenomenon of valence switch is well conserved throughout the animal kingdom and represents an ideal paradigm to address a key question in the neurosciences, i.e. how information processing in neuronal networks leads to behavioural responses. To advance the understanding of valence coding and olfactory processing, the Experienced Researcher (ER) will capitalise on her detailed knowledge of the evolutionary well conserved olfactory system of the fruitfly Drosophila melanogaster, using its powerful genetic and experimental approaches (e.g. Riabinina et al, 2015, Nature Methods; Gao et al, 2015, Nature Neuroscience). The key goal of the project is to identify patterns of neuronal activity that code for odorant valence. To achieve this goal, we will record responses of small subsets of genetically labelled second-order olfactory neurons by patch-clamp while activating olfactory receptor neurons optogenetically or by odorants of known behavioural valence. We will apply statistical and machine learning techniques to detect parameters of neuronal activity, indicative of odorant valence. ", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["701109"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER", "THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 2 171 622,89"], "Project_Title": ["Elucidating the role of ultraviolet radiation in melanoma"], "Total_Cost": ["EUR 2 171 622,89"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["MMUVR"], "Technology_Description": "Melanoma incidence continues to increase across Europe and compared to other cancers, it disproportionately affects young people, causing a significant loss in life-years in those affected. Ultraviolet radiation (UVR) is the only environmental risk factor in melanoma, but the underlying genetic constitution of the individual also plays an important role. However, our knowledge of the gene-gene and gene-environment interactions in melanomagenesis is still very limited and here we will use various cutting-edge technologies to investigate the role of UVR in melanoma initiation and progression. We have developed mouse models of UVR-driven melanoma that closely mimic UVR-driven melanoma in humans and these provide an unprecedented opportunity to dissect how different wavelengths and patterns of UVR exposure affect melanomagenesis. We propose a multidisciplinary programme of work to examine how host genetic susceptibility factors and responses such as DNA damage repair and inflammation affect melanoma development and progression following UVR exposure. We will integrate knowledge from our animal experiments with epidemiological, histopathological, clinical, and genetic features of human tumours to improve stratification of human melanoma and thereby assist clinical management of this deadly disease. Our overarching aim is to develop a validated stratification approach to melanoma patients that will assist in the development of effective public health campaigns for individuals at risk across Europe.", "To": ["2021-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["671262"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Fast particle-based time integrator for incompressible flows simulations"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["FastFlowSim"], "Technology_Description": "The FastFlowSim project\u2019s aim is to develop a fast and accurate particle-based time integrator for the simulation of incompressible flows. The developments will be done within the framework of the particle finite element method and using a semi-Lagrangian semi-implicit formulation of the flow equations. The principal strategy used to attain a faster method is to push further the stability limit of the time integrator which allows us to take larger time steps without deteriorating the accuracy.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["702138"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER", "THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 1 922 451"], "Project_Title": ["Nucleation of Organic Crystals onto 2D materials"], "Total_Cost": ["EUR 1 922 451"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["NOC2D"], "Technology_Description": "The formation of crystalline solids from liquid-phase precursor is a central idea in materials chemistry. Organic crystal structures can be found in a large number of products, including food, explosives, pigments and pharmaceuticals. Control of molecular assembly is therefore a fundamental problem for both research and industry and it involves substantial scientific and economic challenges. For example, polymorphism is crucial for drug manufacturers because the crystal structure, morphology and size, can all affect the stability, efficacy and production cost of the drug. Therefore, it is essential to achieve a deep understanding on the molecular processes happening at the early stage of crystallization. Although important results have been obtained, our understanding on how a crystal of organic molecules nucleates on a surface is still poor. To go beyond state-of-the art we need techniques able to probe rare nucleation events with nanoscale resolution and very high sensitivity, providing direct insights on the structure of the nuclei and their interaction with the environment. ", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["648417"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Unsymmetric diborane(4) compounds for small molecule activation and B-B coupling"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["DIBOR"], "Technology_Description": "Organoboron complexes are ubiquitous in synthesis due to their utility in functional group transformations and the Nobel Prize winning Suzuki-Miyaura reaction. Furthermore, the advent of frustrated Lewis pair chemistry and BB multiple bonds has demonstrated that organoboron compounds can activate small molecules (e.g., CO) and sigma bonds (including H2), reactivity previously thought to be the domain of transition metal catalysts. As part of the renaissance in organoboron chemistry diborane(4) compounds (R2B-BR2) have received considerable interest, particularly that react as boryl anion equivalents. Recent unpublished work at UNIMAN has developed an efficient, scalable route to a synthetically useful unsymmetric diborane(4) compound, specifically (RO)2B-BCl2(NHC), (1, NHC = N-heterocyclic Carbene). The DIBOR project will exploit this breakthrough using 1 (and new congeners synthesised in this fellowship) as key precursors to;", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["703227"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER", "THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 149 250"], "Project_Title": ["A new architecture for visual display technology based upon recent advances in our understanding of visual physiology."], "Total_Cost": ["EUR 149 250"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["MeloVDU"], "Technology_Description": "The last twenty years has seen a huge improvement in the quality of images produced by commercial visual display units. Nevertheless, they still do not fully recreate the range of sensations we experience during natural vision. We have designed a prototype visual display that will allow us to take advantage of recent developments in visual neurophysiology to address that limitation. We request funds to construct this prototype and explore its performance as a necessary proof of concept for its commercialisation.", "To": ["2017-05-31, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2015 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-12-01"], "Project_ID": ["692645"], "Call_for_Proposal": ["ERC-2015-PoC"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Magnetic Sensors based on Two-Dimensional Materials/Si"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["2DSi"], "Technology_Description": "Magnetoresistance sensors based on the change in electrical resistance upon an external magnetic field are widely used in day to day applications. The magnetic sensor industry sells billions of dollars worth of sensors every year and there is an ever-growing demand for magnetic sensors with high sensitivity, small size, low power consumption and low cost with compatibility with existing electronic systems. The project aims to develop a new class of highly sensitive magnetoresistance sensors based on doped Si and two dimensional (2D) layered materials, with a focus on single layer graphene and single layer WS2 which could be easily extended to other low dimensional layered materials. This plan will utilize the advantages of tunnelling through SiO2, gate tunability of 2D materials and the geometry of Si to obtain highly sensitive magnetic sensors from Si, which is very unique and novel. The large magnetoresistance observed in graphene by the applicant's group (Gopinadhan et al. Phys. Rev. B 88, 195429 (2013)) can be utilized to get an additional positive change in total resistance per unit applied magnetic field for higher sensitivity. Si can be integrated monolithically, in contrast, 2D layered materials such as graphene possess excellent electrical, thermal and mechanical properties. Its high mobility of carriers are very attractive for high speed applications. The interface between Si and 2D materials are little explored, however there is an enormous technological interest for applications such as graphene-based transparent electrodes in Si solar cells, high speed non-volatile flash memory, microwave switches, voltage controlled diodes, logic devices etc. Furthermore, most of the existing magnetic sensors are electron based and the possibility of both n and p type magnetic sensors due to the electric field tunability of 2D materials may provide new applications such as magnetic sensor and diode (p-n junction) in one active device.", "To": ["2017-08-02, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-08-03"], "Project_ID": ["659963"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER", "THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 2 294 781"], "Project_Title": ["Developing and delivering neurocomputational models to bridge between brain and mind."], "Total_Cost": ["EUR 2 294 781"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["BRAIN2MIND_NEUROCOMP"], "Technology_Description": "The promise of cognitive neuroscience is truly exciting \u2013 to link mind and brain in order to reveal the neural basis of higher cognitive functions. This is crucial, scientifically, if we are to understand the nature of mental processes and how they arise from neural machinery but also, clinically, if we are to establish the basis of neurological patients\u2019 impairments, their clinical management and treatment. Cognitive-clinical neuroscience depends on three ingredients: (a) investigating complex mental behaviours and the underlying cognitive processes; (b) mapping neural systems and their function; and (c) methods and tools that can bridge the gap between brain and mental behaviour. Experimental psychology and behavioural neurology has delivered the first component. In vivo neuroimaging and other allied technologies allow us to probe and map neural systems, their connectivity and neurobiological responses. The principal aim of this ERC Advanced grant is to secure, for the first time, the crucial third ingredient \u2013 the methods and tools for bridging systematically between cognitive science and systems neuroscience.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["670428"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Novel Electrochemical Exfoliation Approach to the Synthesis of Large Area, Defect-Free and Single Layer Graphene and Its Application in Fuel Cells"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["GRAPHENERGY3"], "Technology_Description": "Large area, scalable production of single layer and defect free graphene is important for its use in industrial applications. Currently, common methods used to prepare graphene include micromechanical cleavage, chemical vapor deposition, and chemical reduction. However, all these methods have their own shortcomings, for example, difficulty in scale-up or poor quality due to significant defects. To address this issue, in this project, we will focus on developing a novel electrochemical cathodic exfoliation approach to produce high quality graphene. Non-covalent edge-functionalization will be employed to open graphite edges. Upon a negative potential applied on the functionalized graphite electrode, H+ cations from protic ionic liquid electrolyte will be inserted into graphite interlayers and be reduced to hydrogen gas to further open the edge of graphite, which will facilitate the larger imidazolium cations to intercalate, expand and completely exfoliate graphite to single layer graphene. This cathodic exfoliation approach is nondestructive to the resultant graphene, and maintains its perfect structure and electronic properties, which will result in high electrochemical stability and benefit the performance of graphene-based fuel cell electrocatalysts. Finally proton exchange membrane fuel cells will be fabricated with graphene based electrocatalysts above and these are expected to exhibit high power density and long term durability, which may produce a promising future energy technology.", "To": ["2017-08-16, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-08-17"], "Project_ID": ["660064"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Borylated Conjugated Materials"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["BORCOM"], "Technology_Description": "Recent work at the University of Manchester has developed an efficient synthetic method for transition metal free electrophilic borylation of aromatics and heteroaromatics. This approach has recently been extended to the fusion of conjugated materials containing the acceptor moiety benzothiadiazole \u2013 a group that is ubiquitous in materials for organic electronics. This functionalization leads to a significant increase in the electron affinity of the materials and a considerable reduction in the band gap, consistent with near-IR emission in organic light emitting diodes (OLEDs), ambipolar organic field effect transistor (OFET) mobility, improved n-type stability and effective light harvesting in organic photovoltaic cells (OPVs). The BORCOM project will use this methodology to deliver novel molecules and polymers that exhibit high electron affinities and small band gaps by functionalization of azole or azine containing acceptors in the conjugated backbone. The performance of the new materials as n-type semiconductors in OFETs, light harvesting and electron acceptors in OPVs and dopants/emitters in OLEDs will be evaluated.", "To": ["2017-06-30, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-07-01"], "Project_ID": ["660149"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Fungal resistance to antifungals is promoted by cell heterogeneity"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["FUNFIT"], "Technology_Description": "The number of people who die from fungal infections is estimated to be equivalent to or greater than the numbers that die from either tuberculosis or malaria. There are only 3 classes of antifungal drugs available to treat these invasive diseases and resistance against these drugs is increasing. In this study I will investigate how antifungal resistance is impacted by cell heterogeneity in the pathogenic fungus Aspergillus fumigatus. The main hypothesis that I will test is that fungal cell heterogeneity provides subpopulations of cells with greater fitness to resist antifungal treatment. I will determine: (1) which features of three distinct fungal cell types contribute to cell heterogeneity; (2) which cell types and subpopulations of these cells show highest resistance or survival against antifungals; and (3) the roles of septal plugging and cell ploidy in the mechanistic basis of fungal cell heterogeneity. Cutting edge technologies that will be used in this study will include: (1) flow cytometry and fluorescence activated cell sorting (FACS) to identify and select cell subpopulations to test their antifungal resistance, (2) automated, high throughput, high content live cell imaging to analyse the resistance of single cells to antifungals, (3) advanced live-cell imaging techniques including GFP photoactivation and fluorescence recovery after photobleaching (FRAP) to identify septal pore plugging; and (4) laser microdissection to further analyse septal pore plugging. With these advanced techniques I will study the mechanistic basis of fungal resistance mediated by cell heterogeneity. My results will ultimately show how fungal cell heterogeneity impacts fitness against antifungal drugs and they will be the starting point for designing novel antifungal therapies that reduce this fitness.", "To": ["2017-05-31, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-06-01"], "Project_ID": ["659003"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Identification of genes and pathways regulated by the HAT activity of MOZ"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["HAT-MOZ-sphere"], "Technology_Description": "The research programme will comprise the study of the Histone acetyl transferase (HAT) MOZ (Monocytic leukaemia Zinc finger) a critical player in the development and maintenance of the haematopoietic system. In addition, translocations of MOZ are associated with Acute Myeloblastic Leukaemia. Given the importance of this protein in haematopoiesis and leukaemogenesis, it would be essential to further understand the function of MOZ and in particular to identify the genes regulated by its HAT activity of MOZ. A mouse line specifically mutated to abrogate the HAT enzymatic activity of MOZ has been developed in the host laboratory, and represents a powerful and unique tool for the study of MOZ HAT activity. Using Chromatin ImmunoPrecipitation followed by sequencing (ChIP-seq), genome wide targets of MOZ will be determined and the consequences of the deletion of its HAT activity on the epigenetic landscape will be investigated through the survey of several histone modifications and RNA polymerase II recruitment. The non-histone targets of MOZ will be identified through the SILAC technique. Finally a MOZ murine leukaemic model has been developed, based on the transduction of bone marrow cells with a retrovirus encoding MOZ-TIF2, one of the fusion proteins involving MOZ. ChIP-seq will be performed in these leukaemic cells to identify genes targeted by MOZ-TIF2 and changes in epigenetic marks at these loci. Overall, this project will provide a better understanding of MOZ HAT activity in haematopoiesis and leukaemogenesis. Crucially, this project will enable Dr Anne Largeot to obtain and develop a wide range of new and transferable skills through a variety of multidisciplinary training programs. Relying on the knowledge and expertise of her supervisor and the exceptionally high calibre of the Cancer Research UK Manchester Institute, this project will enable Dr Anne Largeot to achieve her long-term objective of obtaining a leadership position in a competitive European Institute", "To": ["2017-08-31, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["658625"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["CO2 as a traceless directing group for catalytic meta C-H olefinations"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["metaC-Hfunct"], "Technology_Description": "The development of methods for the transition metal-catalysed functionalization of C-H bonds is revolutionizing synthetic organic chemistry by providing tools to simplify and accelerate the synthesis and modification of a myriad of known and still unknown organic molecules including aromatic compounds. However, in these processes, the ability to discriminate between C-H bonds for subsequent transformation into other functional groups still remains as a major challenge. To date, much progress has been made on developing strategies for the ortho-functionalization of arenes, mainly through the derivatization of the substrates with directing groups. meta-Functionalization approaches, on the other hand, are extremely scarce despite eta-substitution is a widespread motive amongst biologically active molecules. ", "To": ["2017-03-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-04-01"], "Project_ID": ["656841"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["MASS POLITICAL LIFE WRITING"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["POLITICALLIFEWRITING"], "Technology_Description": "Self-narration is extraordinarily common in contemporary culture. The practice constitutes an extremely popular literary genre, is widespread on the internet in the form of diaries updated daily by huge numbers of web users, and is used in organisational training and as a tool in personal therapy education. Employing an interdisciplinary approach \u2013 drawing on social history, sociology, semiotics and textual analysis \u2013 my research project will examine one of the \"archaeological\" elements underpinning this success: the mass political use of the autobiographical form, first by communism and subsequently by feminism after the Second World War, with a focus on the Italian experience. The Italian Communist Party (PCI) was the largest communist party in the Western world, and Italy\u2019s experience of feminism is one of the most significant on the European continent. Both movements made intense political use of the autobiographical form. The Italian communists inherited the activist autobiographical framework characteristic of the Bolshevik experience. Self-narration was a prerequisite to joining the PCI until the second half of the fifties; however, this organisational practice became obsolete over the course of the sixties. The link between autobiographical accounts and political activism was subsequently revived by feminism in the seventies, in the context of consciousness raising groups. The main objectives of the project are the following: A) to analyse the mass political use of the autobiographical account in Italy since the Second World War; B) to use this analysis to produce an innovative interpretation of the actual success of self-narration. They will be fulfilled through research in the archives of the PCI and the Italian feminist movement. I will use Italian historical events as a case study to highlight the obscure political origins of a specific activity \u2013 self-narration \u2013 that unites various contemporary national cultures of Europe in a transnational manner.", "To": ["2017-08-31, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["658297"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Organometallic Single-Molecule Magnets"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["OrganoMag"], "Technology_Description": "In this project, we will develop new single-molecule magnets (SMMs) that combine the strong magnetic anisotropy of lanthanide ions with a series of novel radical ligands. Highly unusual di- and tri-metallic Ln-SMMs are proposed in which the metals are bridged by radicals with heavy Group 15 donor atoms (i.e. the pnictogens, phosphorus-bismuth). The SMM field is dominated by systems with diamagnetic ligands: our radical ligands are novel, hence their applications in single-molecule magnetism will be unprecedented. We will exploit the rich electrochemistry of the proposed ligands: our DFT calculations show that the target heavy pnictogen radical anions have huge spin densities on the donor atoms, hence the diffuse unpaired spin of the radicals will provide a way of switching off the quantum tunnelling mechanisms that otherwise prevent hysteresis. Ultimately, this project introduces the potential for creating SMMs that show hysteresis at unprecedentedly high temperatures.", "To": ["2017-09-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["653784"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Dam-nations? A study on dams, nation-building and transboundary water relations through case-studies from Ethiopia and Tajikistan"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["DAM-NET"], "Technology_Description": "The aim of DAM-NET is to enable the Future Fellow (FF) to carry out a state-of the art research project, investigating how ruling elites can use the symbolic value of a large hydraulic infrastructure to construct and disseminate their particular idea of the nation and legitimize their hold on power. The study will expand on the largely unexplored link between water and social power, bringing new insights into the analysis of transboundary water relations and on the role that discourse and nationalism play in water politics. Throughout a varied set of activities, the project will allow transfer of knowledge and the training of the FF, thus improving his employability and career perspectives.", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["654861"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Neural basis of semantic control"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["NBSC"], "Technology_Description": "Every form of semantically-driven human behavior is supported by semantic \u2018control\u2019, which refers to executive processes that regulate access to semantic knowledge. To understand everyday verbal and nonverbal activities (e.g., speaking, object use), as well as impairments after brain damage, it is crucial to establish how semantic control is implemented in the brain. ", "To": ["2018-01-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-02-01"], "Project_ID": ["658341"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Deaf life narratives in times of transition."], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["DEALS"], "Technology_Description": "The research project concerns deaf people who use a signed language, such as BSL (British Sign Language). It investigates the potential of a culturally familiar practice, storytelling, as a means of promoting agency, resilience and better well being. Using techniques of narrative therapy, narrative analysis and grounded theory, the project will explore the significance of life story work to enhance well being from a cross cultural perspective, engaging with deaf migrants from diverse nation states. It will result in a life story instrument, piloted during the study that exploits the visual learning strengths of deaf people and the properties of visual (non-textual) languages through digital media. It extends current research on narrative methods as a form of cultural brokering and emancipatory methodologies within critical deaf epistemologies.", "To": ["2017-10-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-11-01"], "Project_ID": ["656285"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Multi-modal optical imaging platform for Biology"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["MOIPB"], "Technology_Description": "With the progress of biological investigation, there comes a strong wish or need for imaging biological samples with multi-modality and on different scales. To meet this need, this project will develop a multi-modal 3D optical imaging platform that images on the multi-scale, from tissues to molecules, by integrating optical coherence tomography (OCT), stimulated emission depletion microscopy (STED), and fluorescence correlation spectroscopy (FCS). Incorporation of structured illumination, adaptive optics and focused engineering will improve spatial resolution, imaging depth, and molecular concentration sensitivity. The investigated technique will be tested and applied to biology investigation, including but not limited to, tissue and cell recovery in the Zebrafish (as a model organism) after laser damage. The multi-scale structural and functional image, as well as the dynamics on the protein level provided by this investigation, will potentially reveal tissue and cell recovery mechanisms, and in the long run contribute to the cure of disease along with understanding the mechanisms of tissue damage. This project will advance the state-of-the-art in optical imaging, and create new links between basic research and biological and clinical applications.", "To": ["2018-12-31, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["699718"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER", "THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 1 846 541,99"], "Project_Title": ["Fundamental nuclear properties measured with laser spectroscopy"], "Total_Cost": ["EUR 1 846 541,99"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["FNPMLS"], "Technology_Description": "The prime research theme of this project is the study of short-lived exotic nuclei with laser spectroscopy. Over the next 5 years my team will study the role of three-nucleon forces and their associated influence on nuclear structure and the limits of nuclear existence. This work will investigate the interplay between tensor and central forces and the associated effect on quantum shells in exotic nuclear systems. This proposal will study how the shape of the nucleus is modified at the limits of nuclear existence. We will use innovative laser spectroscopy methods to achieve these goals. The project will be carried out at the ISOLDE facility, CERN, which is the premier radioactive beam facility at the precision frontier. The proposed research activity closely matches the NuPECC (Nuclear Physics European Collaboration Committee) 2010 Long Range Plan. The wider scientific impact of this research will influence modelling explosive stellar processes and nuclear synthesis, understanding the structure of astrophysical compact-objects such as neutron stars and predicting regions of enhanced stability in the super heavy elements. The FNPMLS project will develop ultra-sensitive methodologies that set a new paradigm in laser spectroscopy. It builds on the cutting edge technology of collinear resonance ionization spectroscopy (CRIS) that I have developed during my STFC Advanced Fellowship. The CRIS technique combines the high resolution nature of collinear laser spectroscopy with the high sensitivity of resonance ionization spectroscopy. The research programme and investment outlined in this proposal will place my team in a unique and world leading position. This work will happen in advance of the next generation of radioactive beam facility such as SPIRAL2, FAIR and FRIB and will provide the essential ingredients for future fundamental questions.", "To": ["2020-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-04-01"], "Project_ID": ["648381"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 495 500"], "Project_Title": ["Control of contact interactions for robots acting in the world"], "Total_Cost": ["EUR 1 495 500"], "Country": ["Germany", "Germany"], "Project_ACR": ["CONT-ACT"], "Technology_Description": "What are the algorithmic principles that would allow a robot to run through a rocky terrain, lift a couch while reaching for an object that rolled under it or manipulate a screwdriver while balancing on top of a ladder? Answering this seemingly na\u00efve question resorts to understanding the fundamental principles for robot locomotion and manipulation, which is very challenging. However, it is a necessary step towards ubiquitous robots capable of helping humans in an uncountable number of tasks. The fundamental aspect of both locomotion and manipulation is that the dynamic interaction of the robot with its environment through the creation of physical contacts is at the heart of the tasks. The planning of such interactions in a general manner is an unsolved problem. Moreover, it is not clear how sensory information (e.g. tactile and force sensors) can be included to improve the robustness of robot behaviors. Most of the time, it is simply discarded. CONT-ACT has the ambition to develop a consistent theoretical framework for motion generation and control where contact interaction is at the core of the approach and an efficient use of sensory information drives the development of high performance, adaptive and robust planning and control methods. CONT-ACT develops an architecture based on real-time predictive controllers that fully exploit contact interactions. In addition, the structure of sensory information during contact interactions is experimentally analyzed to create sensor representations adapted for control. It is then possible to learn predictive models in sensor space that are used to create very reactive controllers. The robot constantly improves its performance as it learns better sensory models. It is a step towards a general theory for robot movement that can be used to control any robot with legs and arms for both manipulation and locomotion tasks and that allows robots to constantly improve their performances as they experience the world.", "To": ["2020-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2015-06-01"], "Project_ID": ["637935"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["CONSIGLIO NAZIONALE DELLE RICERCHE"], "EU_Contribution": ["EUR 180 277,20"], "Project_Title": ["Smart Metal Organic Frameworks for Sensing Volatile Organic Compounds"], "Total_Cost": ["EUR 180 277,20"], "Country": ["Italy"], "Project_ACR": ["SmartMOFs"], "Technology_Description": "SmartMOFs targets a new generation of Metal Organic Frameworks (MOFs) for sensing harmful volatile organic compounds (VOCs). The innovation of SmartMOFs is based on a combined sensing approach, where both optical and electrical changes in the MOF material enable the recognition event. The primary step to meet the required combination of specific absorption/emission and conductivity properties is the selection of the MOF structural units, supported by theoretical investigations. The selected units will offer extensive connectivity, flexibility, tunable porosity and functionalization of the inner surface of the network, with groups interacting with the analytes by means of coordination bonds, p-p interactions or hydrogen bonds. Harmful volatile compounds will entail gases and solvents (e.g., alcohols, benzene, hexane, cyclohexane). The SmarMOFs sensors will show increased selectivity and sensitivity with respect to the state-of-the-art. Deposition of the new MOF materials on surfaces to create sensor devices will be accomplished by advanced deposition techniques. SmartMOFs will thus overtake the current bottleneck of processability that limits practical applications of these materials, filling the gap between basic research and marketable applications. The high interdisciplinarity of SmartMOFs and its foreseen applications in the highly relevant area of public health will be a springboard for the Experienced Researcher to start a successful career in the academic or industrial sectors.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations"], "From": ["2017-06-01"], "Project_ID": ["751175"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Sources and sinks for excess Xe and Ar on the Moon"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["XeMoon"], "Technology_Description": "Noble gases trace the evolution of reservoirs inside terrestrial planetary bodies because their isotopic signatures are diagnostic of volatile sources. In addition, original compositions can be modified by radioactive decay of rock forming elements, providing constraints on the chemistry of an interior reservoir and the time at which it was isolated (since when noble gases were retained). Some lunar samples are known to preserve signatures in xenon and argon that were degassed from one or more interior sources to the exosphere, then incorporated into the regolith, potentially allowing this record to be read. In this work I will combine (i) my expertise in lunar evolution, sample characterization and the 40Ar-39Ar system, (ii) the University of Manchester\u2019s expertise in xenon isotope systematics, world-leading instrumentation for xenon isotopic analysis and state-of-the-art sample characterisation facilities, and (iii) expertise relevant to the lunar exosphere from a network of collaborators. With this team, I will (i) determine the range of xenon and argon signatures in lunar regolith samples and the times at which they were incorporated, (ii) develop a model of the lunar exosphere to infer source reservoir compositions from those measured in samples and so (iii) investigate the number of contributing lunar reservoirs, their compositions and their histories. The results of this interdisciplinary study will be disseminated to the range of specialist and non-specialist audiences. They will serve to test models of lunar evolution, allow comparison with the Earth and Mars to gain wider understanding of terrestrial planetary bodies, and stimulate engagement with planetary science. Additionally, I will develop my leadership and teaching skills by completing the University of Manchester\u2019s New Academics Programme, equipping me to move to the next stage of my career as a researcher, leader and teacher for the next generation of multidisciplinary planetary scientists.", "To": ["2020-04-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-05-01"], "Project_ID": ["749815"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM", "ASSOCIATION DES AMIS DE LA MEDECINE SOCIALE", "INSTITUT NATIONAL POLYTECHNIQUE DE TOULOUSE", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSITE PAUL SABATIER TOULOUSE III"], "EU_Contribution": ["EUR 193 500"], "Project_Title": ["Next generation of 3D multifunctional materials and coatings for biomedical applications"], "Total_Cost": ["EUR 274 500"], "Country": ["United Kingdom", "France", "France", "France", "France"], "Project_ACR": ["NEXT-3D"], "Technology_Description": "NEXT-3D is an innovative European-Australian project that consists of 4 academic and 2 non-academic members. The research methodology is based on the multi-disciplinary and inter-sectorial collaboration among the network participants and focuses into main themes: 3D Printing, Enhance Coating, and medical translation with the main aim to develop the next generation of multifunctional 3D materials for orthopaedic and dental implants. Multifunctional materials with drug delivery properties and antibacterial properties are desirable by clinicians. These materials promote healing and can reduce and prevent from unexpected effects on patients. Research will be conducted following a multi- and inter-disciplinary research methodology designed to develop innovative biomedical materials using advanced processing technologies (3D laser printing and sintering) with market potential. The proposed research and innovative programme will lead to the advancement of knowledge in the field and to new materials with superior properties.", "To": ["2018-05-31, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Other", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2015-06-01"], "Project_ID": ["645749"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI PADOVA", "UNIVERSITA DEGLI STUDI DI PADOVA", "TECHNISCHE UNIVERSITEIT DELFT"], "EU_Contribution": ["EUR 1 999 985"], "Project_Title": ["A seamless multi-scale model for contact, friction, and solid lubrication"], "Total_Cost": ["EUR 1 999 985"], "Country": ["Italy", "Italy", "Netherlands"], "Project_ACR": ["FricLess"], "Technology_Description": "Friction and wear are liable for enormous losses in terms of energy and resources in modern society. Costs related to unwanted friction in industrialised countries are estimated to be about 3% of the gross domestic product. Urgency is even greater nowadays as friction between micro-components has become the bottleneck of several applications for which miniaturisation is critical.", "To": ["2021-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["681813"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "UNIVERSITAETSMEDIZIN GOETTINGEN - GEORG-AUGUST-UNIVERSITAET GOETTINGEN - STIFTUNG OEFFENTLICHEN RECHTS"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Neurophysiological Biomarkers of Cortical Plasticity Induced by Neuromodulation"], "Total_Cost": ["EUR 159 461,38"], "Country": ["United Kingdom", "Germany"], "Project_ACR": ["NeuroN"], "Technology_Description": "One of the major issues when dealing with therapies for the rehabilitation of the lower limbs in stroke survivors is the in-deep assessment of their effectiveness and the lack of biomarkers for motor recovery. The motor functionality after therapy is evaluated only through clinical tests and scales which do not give information on the effective muscle state and the changes at the corticospinal level. The aim of restoring the motor functions has moved much of the attention of clinicians and researcher towards the use of the combination of brain stimulation techniques for the assessment of cortical excitability and Brain-Computer Interfaces (BCI) for the control of rehabilitation devices. This intervention induces cortical plasticity and reactivates the closed-loop pathway between the impaired cortical tract and the limb by using the cortical command to drive the device for the generation of the afferent volley. However, nothing is known about the changes of the neurophysiological correlates and how these influence the effective recovery of motor functions. NeuroN represents the first systematic attempt to investigate the neurophysiological correlates of changes in the excitability of the cortical areas responsible for ankle dorsiflexion in chronic hemiparetic stroke survivors with drop foot impairment and to identify novel biomarkers of motor recovery. NeuroN aims at filling the gap of knowledge on the functional effects of increased plasticity in chronic stroke survivors by integrating a BCI robot-based platform with the high-density surface electromyographic (HD-sEMG) recordings. The information coming from the decomposition of HD-sEMG signals give insight into the behavior of the motoneurons in the spinal cord and on the effective control command. NeuroN is expected to address one of the most intriguing issues in the neurorehabilitation field: the novel biomarkers developed will help in shaping new therapies for the recovery of motor function of stroke patients.", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["660905"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["Longitudinal employer\u2013employee perspectives on the role of human capital investments for retirement transitions"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["LEEP"], "Technology_Description": "European and national ageing policies give high priority to increasing retirement age and employability of older people, but no effective solution exists. The project aims to provide practical recommendations based on evidence on the role of human capital investments (at individual and company level) for retirement transitions. This is still an understudied area in ageing research. It is also neglected by policy-makers who miss the fact that employees must be willing and able to work longer, and employers must be willing and able to provide adequate opportunities for extended employment. ", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Research Organisations"], "From": ["2017-10-01"], "Project_ID": ["748671"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich"], "EU_Contribution": ["EUR 2 500 000"], "Project_Title": ["Soft Micro Robotics"], "Total_Cost": ["EUR 2 500 000"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["SOMBOT"], "Technology_Description": "The field of Micro and Nano Robotics has made impressive strides over the past decade as researchers have created a variety of small devices capable of locomotion within liquid environments. Robust fabrication techniques have been developed, some devices have been functionalized for potential applications, and therapies are being actively considered. While excitement remains high for this field, we are facing a number of significant challenges that must be addressed head-on if continued progress towards clinical relevance is to be made. This project will address what we consider to be primary roadblocks to be overcome. This includes the development of bioerodable and non-cytotoxic microrobots, development of autonomous devices capable of self-directed targeting, catheter-based delivery of microrobots near the target, tracking and control of swarms of devices in vivo, and the pursuit of clinically relevant therapies. ", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["743217"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["BILKENT UNIVERSITESI VAKIF", "BILKENT UNIVERSITESI VAKIF"], "EU_Contribution": ["EUR 1 276 640"], "Project_Title": ["Theory and Empirics of Asymmetry"], "Total_Cost": ["EUR 1 276 640"], "Country": ["Turkey", "Turkey"], "Project_ACR": ["TEA"], "Technology_Description": "Why is there a Volcker disinflation but no Bernanke re-inflation? It is not only because of the zero lower bound as a nascent literature is suggesting that monetary policy is more potent in a contractionary stance than in an expansionary stance away from the ZLB as well. But why? Why is it that central banks cut interest rates much faster than they raise them? Why does it seem like financial markets give much different responses to seemingly similar macroeconomic news at different times? Are these all related? ", "To": ["2022-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Turkey"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-03-01"], "Project_ID": ["726400"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 3 146 598"], "Project_Title": ["Cryogenic Rare-event Observatory with Surface Sensitivity"], "Total_Cost": ["EUR 3 146 598"], "Country": ["France", "France"], "Project_ACR": ["CROSS"], "Technology_Description": "CROSS will set the grounds for large-scale experiments searching for neutrinoless double beta decay with zero background at an exposure scale of ~1 tonne x year and with very high energy resolution \u2013 about 1.5\u2030 \u2013 in the region of interest. These features will enable searching for lepton number violation with unprecedented sensitivity, penetrating in prospect the direct-ordering region of the neutrino masses. CROSS will be based on arrays of TeO2 and Li2MoO4 bolometers enriched in the isotopes of interest 130Te and 100Mo, respectively. There are strong arguments in favor of these choices, such as the high double beta transition energy of these candidates, the easy crystallization processes of TeO2 and Li2MoO4, and the superior bolometric performance of these compounds in terms of energy resolution and intrinsic purity. The key idea in CROSS is to reject surface events (a dominant background source) by pulse-shape discrimination, obtained by exploiting solid-state-physics phenomena in superconductors. The surfaces of the crystals will be coated by an ultrapure superconductive aluminium film, which will act as a pulse-shape modifier by delaying the pulse development in case of shallow energy depositions, exploiting the long quasi-particle life-time in aluminium. This method will allow getting rid of the light detectors used up to now to discriminate surface alpha particles, simplifying a lot the bolometric structure and achieving the additional advantage to reject also beta surface events, which unfortunately persist as an ultimate background source if only alpha particles are tagged. The intrinsic modularity and the simplicity of the read-out will make CROSS easily expandable. The CROSS program is focused on an intermediate experiment with 90 crystals, installed underground in the Canfranc laboratory, which will be not only extremely competitive in the international context but also a decisive step to demonstrate the enormous potential of CROSS in terms of background.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["742345"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Cyclic Arylenevinylene Polymers"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["CyclAr"], "Technology_Description": "Research work at the University of Manchester (UNIMAN) has developed an efficient synthetic method to prepare arylenevinylene polymers with control of molecular weight and end-group functionality by the ring-opening metathesis polymerization (ROMP) of strained 1,9-cyclophanedienes. The CyclAr project will use this methodology to deliver conjugated polymers of novel topologies, including rings, 8-shapes, trefoils and others. Macromolecular rings will be prepared by ring expansion metathesis polymerization (REMP) using a tethered ruthenium carbene complex and more complex topologies from telechelic polymers prepared from a bifunctional ruthenium carbene complex. Electron rich (p-type) and electron poor (n-type) polymer topologies will be prepared from the appropriate functionalised cyclophanedienes and topological heterojunctions examined. These molecules will be screened for their photovoltaic performance as the novel molecular topologies can lead to an enhanced charge separation and fewer loss mechanisms - key factors in achieving higher power conversion efficiency in OPVs. The synthetic methodology to be adopted is novel and application of these topological arylenevinylene polymers as semiconducting materials in device fabrication is unprecedented.", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["703125"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Soft Chemical Control of the Physical Properties of Layered Solids"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SOLLAY"], "Technology_Description": "This research programme is fundamental solid state chemistry at the boundary with condensed matter physics. It will discover new transition metal compounds with layered crystal structures and aims to put them on the world stage by exploiting the compositional tunability which is intrinsic to non-molecular systems. The discovery and chemical rationalisation of new composition-structure-property relationships is anticipated to lead eventually to future industrial developments in applications as wide ranging as superconductors, thermoelectric materials, magnetic materials, batteries and heterogeneous catalysis. Parallel to the research, the fellow\u2019s outreach activities will centre on highlighting these \u201csynthetic minerals\u201d to the general public in a permanent exhibit. The host group and the fellow bring complementary expertise to the project and the career development of the fellow will be through the research and outreach and also in the development of collaborations with Oxford Physics, and the world-leading international facilities for neutron and synchrotron X-ray science at the local Harwell campus and in Grenoble.", "To": ["2018-07-25, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-07-26"], "Project_ID": ["658832"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSIDAD POMPEU FABRA", "UNIVERSIDAD POMPEU FABRA", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 1 888 033"], "Project_Title": ["Information Theory with uncertain laws"], "Total_Cost": ["EUR 1 888 033"], "Country": ["Spain", "Spain", "United Kingdom"], "Project_ACR": ["ITUL"], "Technology_Description": "Shannon's Information Theory paved the way for the information era by providing the mathematical foundations of digital information systems. A key underlying assumption of Shannon's key results is that the probability law that governing system is known, allowing to optimize the codebook and decoder accordingly. ", "To": ["2022-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["725411"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["LUNDS UNIVERSITET", "LUNDS UNIVERSITET"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Uncovering targets for ex vivo expansion of hematopoietic stem cells to enhance cell therapies of blood disorders"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["UNEXPECTED"], "Technology_Description": "Mechanisms of self-renewal in hematopoietic stem cells (HSCs) have been subject to intense studies during the last decades. However, this is still a poorly defined process and very limited progress has been made in the long sought goal of expanding HSCs ex vivo to allow for critical improvements of bone marrow transplantation procedures for cancer patients and potentially a broader use of HSCs in gene therapy and regenerative medicine. The aim of this research program is to systematically identify and characterize regulators of self-renewal in human HSCs and to develop strategies for stem cell expansion. Within the project we will develop novel paradigms for CRISPR (clustered regularly interspaced short palindromic repeats) mediated gene editing in primary human HSCs to enable detailed assessment of gene function. We will further employ forward genetic screening approaches based on both CRISPR/Cas9 gene editing and RNA interference (RNAi) gene silencing to identify regulators of renewal and differentiation in human HSCs. Large numbers of HSCs will be targeted with genome-wide lentiviral CRISPR (sgRNA) and short hairpin RNA (shRNA) libraries. Screening assays for HSC self-renewal will be evaluated in a pooled format and de-convoluted using next generation sequencing, allowing thousands of perturbations to be assayed in parallel. Candidate genes from the screens will be studied further using genetic barcoding and transplantations assays in immundeficient mice to test whether they can be targeted to induce expansion of HSCs ex vivo. Finally, based on our findings, we aim to develop GMP compatible conditions for HSC expansion in preparation for clinical trials involving expansion of umbilical cord blood derived stem cells to treat patients with acute leukemia.", "To": ["2020-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-08-01"], "Project_ID": ["648894"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["HERIOT-WATT UNIVERSITY", "HERIOT-WATT UNIVERSITY", "UNIVERSITY OF DUNDEE"], "EU_Contribution": ["EUR 1 999 407"], "Project_Title": ["Real-TIME probing of Ultrafast Phenomena"], "Total_Cost": ["EUR 1 999 407"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom"], "Project_ACR": ["UPTIME"], "Technology_Description": "The perception of the world surrounding us depends on how we illuminate and capture it. For example, our direct observation of high-speed phenomena is limited by the speed of the human visual system. A well known method to visualize fast events is to capture them at very high frame rates with high-speed cameras, and then play the movie in slow-motion, enabling us to understand what happens at short timescales. ", "To": ["2020-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-07-01"], "Project_ID": ["640537"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["MONTANUNIVERSITAT LEOBEN", "STIFTELSEN SINTEF", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "HBI HAERTER GMBH", "BAYERISCHES LASERZENTRUM", "GENERAL ELECTRIC (SWITZERLAND) GMBH", "ACONDICIONAMIENTO TARRASENSE ASSOCIACION"], "EU_Contribution": ["EUR 939 137,50"], "Project_Title": ["Design Study for the European Underground Research Infra-structure related to Advanced Adiabatic Compressed Air Energy Storage"], "Total_Cost": ["EUR 1 373 637,50"], "Country": ["Austria", "Norway", "Switzerland", "Germany", "Germany", "Switzerland", "Spain"], "Project_ACR": ["RICAS2020"], "Technology_Description": "Challenges like climate change, economic, social and sustainable development as well as security are closely linked to the energy supply of European societies. In 2009, the European Union adopted a \u2018climate and energy package\u2019 including that at least 20% of EU gross final energy consumption have to come from renewable energy sources until 2020. The challenge of RICAS2020 is given by intermittent renewable energy sources which require increased energy storage to time shift this energy to meet daily demand. As a consequence, the demand for technologies for providing and storing energy is consequently increasing. ", "To": ["2018-05-31, ongoing project"], "Meta": [""], "Topic_s": ["INFRADEV-1-2014 - Design studies"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations"], "From": ["2015-06-01"], "Project_ID": ["654387"], "Call_for_Proposal": ["H2020-INFRADEV-1-2014-1"]}, -{"Partners": ["ROYAL COLLEGE OF SURGEONS IN IRELAND", "UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN"], "EU_Contribution": ["EUR 175 866"], "Project_Title": ["Local delivery of PTH(1-34) from an injectable collagen-hydroxyapatite scaffold for non-invasive treatment of bisphosphonate associated atypical femoral fractures"], "Total_Cost": ["EUR 175 866"], "Country": ["Ireland", "Ireland"], "Project_ACR": ["InjectCHA"], "Technology_Description": "Having recently returned to the EU following Postdoctoral training in Australia, I hope to work as a MSCA Reintegration Fellow to tackle a devastating clinical orthopaedic challenge for which there is currently no effective treatment. Specifically, bisphosphonate (BP) associated atypical femoral fractures (AFFs) in osteoporotic patients which are associated with excruciating pain and high levels of morbidity and mortality. The scientific goal of this proposal is to integrate my tools in bone tissue engineering with the advanced drug delivery expertise of Prof. David Brayden\u2019s group at University College Dublin (UCD) to develop a novel injectable therapeutic scaffold as a non-invasive treatment for AFFs. This proposal outlines an innovative research project that aims to implement a revolutionary strategy utilising Teriparatide (PTH-(1-34)) to target BP remobilisation away from AFF site and induce bone repair. In addition, a tissue engineering strategy will be employed that combines a regenerative, load bearing biomaterial for controlled local delivery of PTH(1-34) as a pioneering advance for AFF treatment. As a newly appointed academic, the training objective of this grant is to attain the requisite scientific and complementary skills to successfully develop an independent research programme. This will be achieved through the expert supervision and input of Prof. Brayden and backed up by colleagues in the lab and UCD staff training activities. In addition, by managing the project, I will further develop skills relating to planning and reporting, financial management, dissemination, patent filing and commercialisation. I will also avail of opportunities to recruit and supervise students on this project or related works. In summary, this grant will provide invaluable help to establish an independent research niche in active and emerging research fields, while equipping me with the skills needed as a newly appointed lecturer embarking on an independent research career.", "To": ["2018-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["705994"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU", "INSTITUTO SUPERIOR TECNICO", "UNIVERSIDADE DO PORTO", "LINKOPINGS UNIVERSITET", "UNIVERSIDAD DE SEVILLA", "MARITIME ROBOTICS AS", "NORUT NORTHERN RESEARCH INSTITUTE AS", "FUNDACION ANDALUZA PARA EL DESARROLLO AEROESPACIAL", "HONEYWELL INTERNATIONAL SRO", "INNOVATIONSGESELLSCHAFT TECHNISCHE UNIVERSITAT BRAUNSCHWEIG MBH"], "EU_Contribution": ["EUR 3 851 102,88"], "Project_Title": ["Autonomous Unmanned Aerial Systems for Marine and Coastal Monitoring"], "Total_Cost": ["EUR 3 851 103,31"], "Country": ["Norway", "Portugal", "Portugal", "Sweden", "Spain", "Norway", "Norway", "Spain", "Czech Republic", "Germany"], "Project_ACR": ["MarineUAS"], "Technology_Description": "European countries have vast coasts and economic zones that go far into the Atlantic and Arctic oceans and are challenging to monitor and manage. The need to protect and manage the vulnerable natural environment and marine resources in a sustainable manner is an important policy that is manifested in European legislation such as the European Strategy for Marine and Maritime Research. Moreover, the drive towards activities in more remote locations and harsher environment demands new approaches and technologies. A key technology is the increased use of autonomous unmanned aerial vehicle systems (UAS) instead of manned aircraft, buoys, ships or satellite-based remote sensing. UAS offers potential advantages such as high endurance, reduced cost, increased flexibility and availability, rapid deployment, higher accuracy or resolution, and reduced risk for humans and negative impact on the environment. ", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["642153"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["STICHTING VU", "THE UNIVERSITY OF NOTTINGHAM", "UNIVERSITY OF GLASGOW", "BAYERISCHE JULIUS-MAXIMILIANS UNIVERSITAT WURZBURG", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE", "UNIVERSIDAD AUTONOMA DE MADRID", "ARGEN-X", "GRIFFIN DISCOVERIES BV"], "EU_Contribution": ["EUR 3 893 983,56"], "Project_Title": ["ONCOgenic Receptor Network of Excellence and Training"], "Total_Cost": ["EUR 3 893 983,56"], "Country": ["Netherlands", "United Kingdom", "United Kingdom", "Germany", "France", "Germany", "France", "Spain", "Belgium", "Netherlands"], "Project_ACR": ["ONCORNET"], "Technology_Description": "Cancer is a leading health concern. There is a need to fully understand the fundamental processes underlying development of cancer. There is increasing evidence that G protein-coupled receptors (GPCRs) and their associated signalling cascades are involved in both cancer progression and metastasis. As oncogenic GPCRs are likely to be amenable to manipulation via drugs they are ideal therapeutic targets. In ONCORNET (Oncogenic Receptor Network of Excellence and Training) we propose to target two oncogenic GPCRs; the chemokine receptors CXCR4 and CXCR7. These are highly expressed in a range of tumours and yet their role in cancer progression is not well understood. We will focus on unravelling how CXCR4 and CXCR7 are or can be modulated (small molecules, pepducins, nanodies) and investigate the effects on oncogenic responses. This represents crucial knowledge that we currently do not have and yet may well provide potential leads for drug development and commercialisation. ONCORNET will bring together the leading research scientists and labs in Europe with an interest in GPCRs and 15 early stage researchers. We will employ all the latest multidisciplinary research technologies to understand the role of these GPCRs in cancer and develop CXCR4 and CXCR7 tools for diagnostic and therapeutic purposes. Importantly, developed approaches can be extrapolated to other oncogenic GPCRs. The ONCORNET consortium will offer an extensive multidisciplinary training programme to the ESRs to ensure that they can operate in today\u2019s drug discovery programmes. This will include both research (e.g. drug discovery, proteomics, imaging, modelling) and transferable (e.g. entrepreneurship, writing, media training) skill sets \u2013that is rarely offered at PhD level. We will train ESRs to develop the next generation of multidisciplinary scientists with skills that are highly demanded by many of today\u2019s employers in drug development industries.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["641833"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["UNIVERSITE PARIS III SORBONNE NOUVELLE"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Rethinking Work: Intellectual Responses to the 2008 Financial Crisis in French Film and Media"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["WORKRETHINK"], "Technology_Description": "Social critics have observed how, since the 1970s, many forms of work have become increasingly redundant due to technological advances. At the same time, Europe has witnessed economic crises, financialization, growing inequality and debt, yet also responses to these phenomena in, for example, movements advocating debt relief and a citizens\u2019 basic income. These issues have become particularly acute in the wake of the 2008 financial crisis. In France since the crisis there has been an increase in rhetoric surrounding the notion of work as well as many films engaging with this issue.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["708042"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["ACADEMISCH ZIEKENHUIS GRONINGEN", "OTTO-VON-GUERICKE-UNIVERSITAET MAGDEBURG", "UNIVERSITY OF YORK", "H. Lundbeck A/S", "Fondazione Stella Maris", "UNIVERSITEIT UTRECHT", "HADASSAH MEDICAL ORGANIZATION", "PATTERN RECOGNITION COMPANY GMBH", "BRAIN INNOVATION BV", "WHITEMATTER LABS GMBH"], "EU_Contribution": ["EUR 3 886 818,12"], "Project_Title": ["Training the Next Generation of European Visual Neuroscientistsfor the benefit of innovation in health care and high-tech industry"], "Total_Cost": ["EUR 3 886 818,12"], "Country": ["Netherlands", "Germany", "United Kingdom", "Denmark", "Italy", "Netherlands", "Israel", "Germany", "Netherlands", "Germany"], "Project_ACR": ["NextGenVis"], "Technology_Description": "The human visual brain can learn and adapt to change, which solves many of the problems posed by an ever-changing visual environment. However, to maintain a consistent overall representation of the visual world, the brain also has to retain previously acquired neuronal mechanisms. The key is to strike a balance between plasticity and stability.", "To": ["2019-02-28, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-03-01"], "Project_ID": ["641805"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["SCHOOL OF ORIENTAL AND AFRICAN STUDIES, UNIVERSITY OF LONDON", "SCHOOL OF ORIENTAL AND AFRICAN STUDIES, UNIVERSITY OF LONDON", "UNIVERSITAT TRIER", "THE UNIVERSITY OF BIRMINGHAM", "FREIE UNIVERSITAET BERLIN"], "EU_Contribution": ["EUR 2 499 618"], "Project_Title": ["The Multimedia Yasna"], "Total_Cost": ["EUR 2 499 618"], "Country": ["United Kingdom", "United Kingdom", "Germany", "United Kingdom", "Germany"], "Project_ACR": ["MUYA"], "Technology_Description": "What exactly are the words which priests recite in the Yasna, the core ritual of one of the most ancient and influential living religions, Zoroastrianism? What is their meaning and how do they relate to the ritual actions? The Yasna is significant for our cultural heritage not only because of its influential thought system which arguably impacted on post-exilic Judaism, nascent Christianity and Islam, but also because with parts of it going back to the 2nd millennium BCE, it is the oldest witness to Iranian languages. Its full appreciation, however, is severely hampered by the presence of outdated editions and translations or by their absence altogether. Moreover, the relationship between the text recited and the action performed during the ritual is unexplored due to a lack of documentary evidence. The Multimedia Yasna proposes to fill these gaps in a methodologically ground-breaking fashion.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["694612"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["UNIVERSIDAD DE SEVILLA"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Bond Activation and Catalysis by Transition Metal Frustrated Lewis Pairs"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["TM-FLPS"], "Technology_Description": "Catalysis is critical to the delivery of future growth in the manufacturing sector: ca. 75% of all chemicals currently require catalysts at some stage in their manufacture, with catalytic processes generating \u20ac1,000 Bn in products world-wide. This proposal targets a step-change in homogenous catalysis by approaching it from a new perspective. Frustrated Lewis Pairs (FLPs) are among the most promising new avenues for the development of future catalysts and offer important advantages in the context of sustainability. Thus the young field of FLP chemistry has experienced an enormous expansion since its founding discoveries one decade ago. However, this rapid development contrasts with the very limited number of examples in the literature in which one of the Lewis acid/base (LA/B) components is based on a transition metal. The current proposal aims to combine the rich chemistry of transition metals (ultimately Earth-abundant elements) with the powerful reactivity offered by FLP systems by substituting one of its LA/B components by a transition metal. The extraordinary structural diversity of transition metals, along with the rich variety of elementary reactions that take place over those centres, are attributes that will extend the usefulness of FLPs far beyond the present (mainly) hydrogenation reactions and should allow developing new catalytic processes unreachable for current homogeneous catalysts. The possibilities are as unexplored as unlimited. We aim to exploit Pt and Au systems, for which preliminary results are available in the host group and will give high confidence of short-term success. Subsequently we will build on the key principles so established to expand our approach to ecologically more benign first-row transition metals. The potential in bond activation and catalysis of the resulting transition metal FLP systems will be explored with the ultimate goal of developing novel catalytic cycles of industrial relevance.", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["706008"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSIDAD PUBLICA DE NAVARRA"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Disentangling the effects of CO2 fertilization, nutrient limitation and water availability on forest ecosystem processes: Estimating their long-term consequences on SW European forests"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["DENDRONUTRIENT"], "Technology_Description": "European forestry is fast evolving as forests could experience in the near future important changes in climate and also in management, which is moving from timber production to values such as bioenergy, carbon sequestration, biodiversity and others. These factors could change the idoneity of traditional forestry in Scots pine forests (which cover important areas in Europe). The project\u00b4s objectives are: 1) To characterize past and estimate future effects of forest management and climate change on carbon and nutrient budgets in Pinus sylvestris stands in SW Europe, to support sustainable forestry that maximizes nutrient and carbon use efficiency and therefore tree growth; 2) To develop, evaluate and apply reliable ecologically-based mathematical models that can be applied in forest management, to study interactions among elevated atmospheric CO2, tree growth and limiting nutrients and moisture. To achieve these objectives the project will be implemented in three stages: 1) Field and archival samples form experimental plots in Scot pine stands in the Pyrenees will be used to analyze connections between soil, leaf and stem nutrient status in the last 16 years. The magnitude of ecosystem biomass and nutrient pools will be estimated to calculate the historical change of nutrient use efficiency by the pines. Historical leaf NUE will be estimated through leaf area scanning combined with chemical analysis. Stem water and nutrient status will be estimated by wood scanning combined with techniques discriminating isotopes of carbon and nitrogen. 2) The ecosystem model FORECAST-Climate will be calibrated, validated, and used as a virtual lab to test the relative importance of nutrient, water, and CO2 availability on tree growth. 3) A battery of climate change (temperature, precipitation and CO2 concentration) and forest management scenarios will be simulated to assess their long-term consequences and provide guidelines on the potential consequences of each management option.", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["656810"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSIDAD AUTONOMA DE MADRID"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Changing the course of cognitive decline in normal aging with positive emotions by training brain plasticity"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["MEMOTION"], "Technology_Description": "Aging is a primary health concern for all European countries and the entire world. Healthy adults experience memory declines that affect daily functioning, yet their ability to process emotion is well-preserved. The benefit of utilizing older adults spared emotional abilities to help mitigate memory declines has not been previously explored and will have substantial implications for daily life. The current project has two main goals. First, we will employ cutting-edge functional imaging technology to investigate age-related neural interactions between emotion and memory. To this end, electroencephalography (EEG) will record electrical brain activity non-invasively while participants perform an innovative memory task with an emotional component. Second, we will implement an innovative memory training programme to test brain plasticity, with a focus on transferring these benefits to daily life. It will enhance the importance of age-related preserved emotions to improve memory deficits. EEG activity will be recorded before and after training to examine the neural changes as a result of training. Besides the extensive research experience of the applicant in fundamental research of aging, the novel approach will be to conduct this project by synergizing key aspects of fundamental and applied sciences, emphasizing transfer of knowledge and collaboration with industry. There is a clear benefit of the mobility for both the applicant and the host, ensuring high quality results and dissemination. In this regard, the host will ensure the acquisition of new technical, management, tutorial and transferable skills. The applicant will also benefit from a multidisciplinary environment enhancing international collaboration that will surely contribute to diversify her career. Finally, via a specialized Career Development Plan, the host will provide the ideal training and validation environment, through which the applicant will reach unprecedented levels of professional maturity", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["660031"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITE DE LORRAINE", "UNIVERSITE DE LORRAINE"], "EU_Contribution": ["EUR 2 810 229"], "Project_Title": ["Isotope Fractionation of Light Elements Upon Ionization: Cosmochemical and Geochemical Implications"], "Total_Cost": ["EUR 2 810 229"], "Country": ["France", "France"], "Project_ACR": ["Photonis"], "Technology_Description": "Light elements such as hydrogen and nitrogen present large isotope variations among solar system objects and reservoirs (including planetary atmospheres) that remain unexplained at present. Works based on theoretical approaches are model-dependent and do not reach a consensus. Laboratory experiments are required in order to develop the underlying physical mechanisms. The aim of the project is to investigate the origins of and processes responsible for isotope variations of the light elements and noble gases in the Solar System through an experimental approach involving ionization of gaseous species. We will also investigate mechanisms and processes of isotope fractionation of atmophile elements in planetary atmospheres that have been irradiated by solar UV photons, with particular reference to Mars and the early Earth. Three pathways will be considered: (i) plasma ionisation of gas mixtures (H2-CO-N2-noble gases) in a custom-built reactor; (ii) photo-ionisation and photo-dissociation of the relevant gas species and mixtures using synchrotron light; and (iii) UV irradiation of ices containing the species of interest. The results of this study will shed light on the early Solar System evolution and on processes of planetary formation.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["695618"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["UNIVERSIDAD AUTONOMA DE MADRID", "UNIVERSIDAD AUTONOMA DE MADRID"], "EU_Contribution": ["EUR 1 704 375"], "Project_Title": ["Using extreme magnetic field microscopy to visualize correlated electron materials"], "Total_Cost": ["EUR 1 704 375"], "Country": ["Spain", "Spain"], "Project_ACR": ["PNICTEYES"], "Technology_Description": "Strong electronic correlations often produce intertwined phases where multiple length scales coexist. These produce spatially varying electronic properties containing unique insight on the many-body effects that determine the emergence of novel collective behavior. Addressing the problem of electron correlations requires powerful microscopes probing electronic properties down to atomic scale.", "To": ["2021-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["679080"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Ostreid herpesvirus 1: Genetic selection of Resistant strains and environmental interaction in the Atlantic coast of Spain (Galicia)"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["ResisGal"], "Technology_Description": "One of the main concerns in the aquaculture sector is the significant mortality of the Pacific oyster, Crassostrea gigas, the principal shellfish cultivated worldwide. Among other factors, the presence of a virus has been directly associated with these mortality events which can largely exceed normal losses. The economic impact of the disease in oyster production has reached worrying levels since it has been spread to important producer countries in both hemispheres. ", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2015-09-01"], "Project_ID": ["659072"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSIDAD DE SEVILLA", "UNIVERSIDAD DE SEVILLA"], "EU_Contribution": ["EUR 1 106 936"], "Project_Title": ["Analysis of moving incompressible fluid interfaces"], "Total_Cost": ["EUR 1 106 936"], "Country": ["Spain", "Spain"], "Project_ACR": ["FLUID-INTERFACE"], "Technology_Description": "The research of this proposal is focused on solving problems that involve the evolution of fluid interfaces. The project will investigate the dynamics of free boundaries arising between incompressible fluids of different nature. The main concern is well-posed scenarios which include the possible formation of singularities in finite time or existence of solutions for all time. These contour dynamics issues are governed by fundamental fluid mechanics equations such as the Euler, Navier-Stokes, Darcy and quasi-geostrophic systems. They model important problems such as water waves, viscous waves, Muskat, interface Hele-Shaw and SQG sharp front evolution. All these contour dynamics frameworks will be studied with emphasis on singularity formation and global existence results, not only for their importance in mathematical physics, but also for their mathematical interest. This presents huge challenges which will in particular require the use of different tools and methods from several areas of mathematics. A new technique, introduced to the field by the Principal Investigator, has already enabled the analysis of several singularity formations for the water waves and Muskat problems, as well as to obtain global existence results for Muskat. The main goal of this proposal is to develop upon this work, going far beyond the state of the art in these contour dynamics problems for incompressible fluids.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["639227"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["THE UNIVERSITY OF SHEFFIELD"], "EU_Contribution": ["EUR 237 493,80"], "Project_Title": ["\u201cCan bean yield losses caused by drought, heat stress and climate change be ameliorated by enhancing pod-specific stomatal conductance?\u201d"], "Total_Cost": ["EUR 237 493,80"], "Country": ["United Kingdom"], "Project_ACR": ["Pod Yield"], "Technology_Description": "CO2-induced climate change is causing global warming and droughts, resulting in crop yield losses. Common bean (Phaseolus vulgaris) is among the most important food crops worldwide, but is very vulnerable to heat- and drought-induced yield losses. The key objective of this project is to experimentally test the potential for increased pod transpiration to enhance bean pod yield under climate-change-associated drought and heat stress. I will fill an empirical void by, for the first time, testing this critical hypothesis in (1) naturally drought- and heat- tolerant tepary bean (Phaseolus acutifolius) using transcriptomic analysis, and (2) by transgenic enhancement of pod-specific stomatal conductance in the stress-intolerant common bean (P. vulgaris). For comparative transcriptomic analysis of Phaseolus pod drought and heat responses I will be trained in RNAseq, and for transgenic experiments I will produce stable Phaseolus transformants and characterise pod water flux by cutting-edge terahertz spectroscopy during the out-going phase in the lab of Prof. Covarrubias at the Institute of Biotechnology, National Autonomous University of Mexico (IBT-UNAM). I have designed a soybean promoter-driven construct that will direct expression of a dominant Arabidopsis allele to enhance Phaseolus pod stomatal opening and this will be compatible for use in many legume crops. To transfer this important agri-tech innovation back to Europe, I will characterise tepary bean and the transgenic plant\u2019s growth and yield responses to a Future Climate Change Scenario during the return phase at the beneficiary, the University of Sheffield (USFD). At the USFD the group of Prof. Gray has unique expertise in stomatal and guard cell responses to elevated [CO2] and combines infrared thermography and infrared-gas analysis to phenotype whole-plant CO2 growth responses. The project uses an interdisciplinary and translational approach to tackle food security issues under climate change.", "To": ["2020-06-11, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-12"], "Project_ID": ["700867"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["FUNDACION DEUSTO", "FUNDACION DEUSTO", "UNIVERSIDAD AUTONOMA DE MADRID"], "EU_Contribution": ["EUR 2 065 125"], "Project_Title": ["Dynamic Control and Numerics of Partial Differential Equations"], "Total_Cost": ["EUR 2 065 125"], "Country": ["Spain", "Spain", "Spain"], "Project_ACR": ["DYCON"], "Technology_Description": "This project aims at making a breakthrough contribution in the broad area of Control of Partial Differential Equations (PDE) and their numerical approximation methods by addressing key unsolved issues appearing systematically in real-life applications. ", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["694126"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["COLLEGE DE FRANCE", "COLLEGE DE FRANCE"], "EU_Contribution": ["EUR 2 249 196,25"], "Project_Title": ["Anionic redox processes: A transformational approach for advanced energy materials"], "Total_Cost": ["EUR 2 249 196,25"], "Country": ["France", "France"], "Project_ACR": ["ARPEMA"], "Technology_Description": "Redox chemistry provides the fundamental basis for numerous energy-related electrochemical devices, among which Li-ion batteries (LIB) have become the premier energy storage technology for portable electronics and vehicle electrification. Throughout its history, LIB technology has relied on cationic redox reactions as the sole source of energy storage capacity. This is no longer true. In 2013 we demonstrated that Li-driven reversible formation of (O2)n\uf02d peroxo-groups in new layered oxides led to extraordinary increases in energy storage capacity. This finding, which is receiving worldwide attention, represents a transformational approach for creating advanced energy materials for not only energy storage, but also water splitting applications as both involve peroxo species. However, as is often the case with new discoveries, the fundamental science at work needs to be rationalized and understood. Specifically, what are the mechanisms for ion and electron transport in these Li-driven anionic redox reactions? ", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["670116"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["UNIVERSIDAD DE SEVILLA", "UNIVERSIDAD DE SEVILLA"], "EU_Contribution": ["EUR 2 843 750"], "Project_Title": ["Molecular mechanisms of acute oxygen sensing."], "Total_Cost": ["EUR 2 843 750"], "Country": ["Spain", "Spain"], "Project_ACR": ["OxygenSensing"], "Technology_Description": "Oxygen (O2) is essential for life on Earth. This proposal deals with the study of the molecular mechanisms underlying acute O2 sensing by cells, a long-standing issue that is yet to be elucidated. In recent years, the discovery of hypoxia inducible transcription factors and their regulation by the O2-dependent hydroxylases has provided a solid framework for understanding genetic responses to sustained (chronic) hypoxia. However the mechanisms of acute O2 sensing, necessary for the activation of rapid, life-saving, compensatory respiratory and cardiovascular reflexes (e.g. hyperventilation and sympathetic activation), are unknown. While the primary goal of the project is to characterize the molecular mechanisms underlying acute O2 sensing by arterial chemoreceptors (carotid body \u2013CB- and adrenal medulla \u2013AM-), we will also extend our study to other organs (e.g. pulmonary and systemic arteries) of the homeostatic acute O2-sensing system. We will investigate the role of mitochondria, in particular complex I (MCI), in acute O2 sensing. Previous data from our group demonstrated that rotenone, a MCI blocker, selectively occludes responsiveness to hypoxia in CB cells. In addition, our unpublished data indicate that sensitivity to hypoxia (but not to other stimuli) is lost in mice with genetic disruption of MCI genes in CB and AM cells. We have shown that the adult CB is a plastic organ that contains a population of multipotent neural stem cells. Hence, another objective of the project is to study the role of these stem cells in CB modulation (over- or infra-activation), which may participate in the pathogenesis of diseases. In the past, our group has made seminal contributions to unveiling the cellular bases of arterial chemoreception. The discovery of stem cells in the CB and the generation of new genetically modified mouse models, put us in a leading position to elucidate the molecular bases of acute O2 sensing and their biomedical implications.", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-11-01"], "Project_ID": ["669220"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["ATHINA-EREVNITIKO KENTRO KAINOTOMIAS STIS TECHNOLOGIES TIS PLIROFOFORIAS, TON EPIKOLNONION KAI TIS GNOSIS", "UNIVERSITAT DE BARCELONA", "INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE", "UNIVERSITAT LINZ", "STIFTELSEN SINTEF", "UNIVERSITY OF STRATHCLYDE", "TECHNISCHE UNIVERSITAET WIEN", "Evolute GmbH"], "EU_Contribution": ["EUR 3 408 202,08"], "Project_Title": ["Algebraic Representations in Computer-Aided Design for complEx Shapes"], "Total_Cost": ["EUR 3 408 202,08"], "Country": ["Greece", "Spain", "France", "Austria", "Norway", "United Kingdom", "Austria", "Austria"], "Project_ACR": ["ARCADES"], "Technology_Description": "ARCADES aims at disrupting the traditional paradigm in Computer-Aided Design (CAD) by exploiting cutting-edge research in mathematics and algorithm design. Geometry is now a critical tool in a large number of key applications; somewhat surprisingly, however, several approaches of the CAD industry are outdated, and 3D geometry processing is becoming increasingly the weak link. This is alarming in sectors where CAD faces new challenges arising from fast point acquisition, big data, and mobile computing, but also in robotics, simulation, animation, fabrication and manufacturing where CAD strives to address crucial societal and market needs. The challenge taken up by ARCADES is to invert the trend of CAD industry lagging behind mathematical breakthroughs and to build the next generation of CAD software based on strong foundations from algebraic geometry, differential geometry, scientific computing, and algorithm design. Our game-changing methods lead to real-time modelers for architectural geometry and visualisation, to isogeometric and design-through-analysis software for shape optimisation, and marine design & hydrodynamics, and to tools for motion design, robot kinematics, path planning, and control of machining tools. One of the Network SMEs estimates that the innovative impact of ARCADES may enable them to get ahead of competition for up to 2 years, thus benefiting about 40% of their customers. The participants span a multidisciplinary and multisectoral spectrum for realising our vision, all being international leaders at various stages of the pipeline. They form an outstanding ecosystem for training the next generation of applied mathematicians, computer scientists and engineers for achieving our scientific breakthroughs, and who are equipped with a double career advantage: excellent research training, and exposure to industrial research environments through a nexus of secondments among Universities, Research and Innovation Centers, and industrial teams.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Greece"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-01-01"], "Project_ID": ["675789"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI MILANO", "THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN", "UNIVERSITEIT ANTWERPEN", "UNIVERSITAT DE BARCELONA", "ACADEMISCH ZIEKENHUIS LEIDEN"], "EU_Contribution": ["EUR 3 086 435,52"], "Project_Title": ["Modulation of glycolytic flux as a new approach for treatment of atherosclerosis and plaque stabilization: a multidisciplinary study"], "Total_Cost": ["EUR 3 086 435,52"], "Country": ["Italy", "United Kingdom", "Belgium", "Spain", "Netherlands"], "Project_ACR": ["MOGLYNET"], "Technology_Description": "The mission of MoGlyNet is to define a joint doctorate educational training model in Drug Discovery and Development where Academia and Industry join their forces for:", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-EJD - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-EJD)"], "Funding_scheme": ["MSCA-ITN-EJD - European Joint Doctorates"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["675527"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["UNIVERSITEIT MAASTRICHT", "UNIVERSITEIT MAASTRICHT"], "EU_Contribution": ["EUR 1 799 034,44"], "Project_Title": ["Migrant Life Course and Legal Status Transition"], "Total_Cost": ["EUR 1 799 034,44"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["MiLifeStatus"], "Technology_Description": "When does citizenship provide a boost to migrant integration? A fast-track to citizenship can maximise the potential for settlement success, though too short a pathway can disincentivise integration. Not all migrants have an equal interest in naturalising and some are discouraged by restrictive policies. Yet little is known about why, how and for whom legal status transition matters and, especially, how policy variation impacts on this relation. Which migrants are most discouraged by stricter requirements for naturalisation? For whom carries citizenship the largest pay-off? Does it still matter if a migrant acquires citizenship after a long waiting period? This project combines for the first time the ideas that a) migrants have different motivations to naturalise; b) legal status transitions are conditioned by the institutional and socioeconomic contexts in origin and destination countries and c) the potential \u2018integration premium\u2019 associated with naturalisation is conditioned by the trajectory into citizenship. ", "To": ["2021-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-08-01"], "Project_ID": ["682626"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["HUMANITAS UNIVERSITY", "HUMANITAS UNIVERSITY", "ISTITUTO EUROPEO DI ONCOLOGIA SRL"], "EU_Contribution": ["EUR 2 500 000"], "Project_Title": ["The inflammatory gene expression program in macrophages: An integrative approach for the systematic characterization of transcriptional co-regulators"], "Total_Cost": ["EUR 2 500 000"], "Country": ["Italy", "Italy", "Italy"], "Project_ACR": ["MEDICI"], "Technology_Description": "Tissue responses to microbial and endogenous danger signals involve the activation of both resident and monocyte-derived macrophages, as well as the coordinated inducible expression of hundreds of inflammatory genes. Gene transcription is controlled by the information contained in thousands of genomic regulatory elements (enhancers and promoters), which is first read by transcription factors (TFs) and then integrated and relayed to the transcriptional machinery via an array of co-regulators with disparate biochemical activities and functions. The recent work of several groups, including our own, has extensively characterized how in macrophages the genomic regulatory sequences controlling inflammatory gene expression are coordinately bound and activated by myeloid lineage-determining TFs and broadly expressed stimulus-activated TFs. However, we still have a very incomplete understanding of the necessary next step in the process, namely how distinct combinations of DNA-bound TFs regulate recruitment and function of the co-regulators and machineries that control gene transcription. ", "To": ["2021-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-11-01"], "Project_ID": ["692789"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["UNIVERSIDAD AUTONOMA DE MADRID"], "EU_Contribution": ["EUR 1 274 400"], "Project_Title": ["Programme for Post-Doctoral Talent Attraction to CEI UAM+CSIC"], "Total_Cost": ["EUR 2 548 800"], "Country": ["Spain"], "Project_ACR": ["InterTalentum"], "Technology_Description": "The Programme for Post-Doctoral Talent Attraction to CEI UAM+CSIC, InterTalentum, is a programme developed by the Universidad Aut\u00f3noma de Madrid (UAM), which intends on building particularly favourable environment to attract the best experienced researchers in the four Focus Research Areas of CEI UAM+CSIC: Biology and Biomedicine, Nanoscience, Nanotechnology and Advanced Materials, Theoretical Physics and Mathematics and Social Sciences, Legal Sciences and Humanities. The program aims at exploiting the full potential of the CEI UAM+CSIC to offer the fellows a truly interdisciplinary and intersectorial training that will strengthen their curricula and provide the region of Madrid with a pool of researchers capable of preserving the long standing tradition for scientific excellence and bridging the gap between academic and applied research. Within the proposed 60 months co-funding period (48 months of fellowships), distributed in two International Calls, InterTalentum will offer to 18 incoming experienced researchers, of any nationality, the opportunity to develop her/his research project within the framework of a vast network of institutions participating under CEI UAM+CSIC, an International Excellence initiative and a Global Campus, including some worldwide reference research laboratories at Universidad Aut\u00f3noma de Madrid (UAM, included its Joint Research Institutes and Health Institutes), Consejo Superior de Investigaciones cient\u00edficas (CNB - Centro Nacional de Biotecnolog\u00eda, ICMM - Instituto de Ciencia de Materiales de Madrid, ICP - Instituto de Cat\u00e1lisis y Petroqu\u00edmica , ICV - Instituto de Cer\u00e1mica y Vidrio, IMM - Instituto de Microelectr\u00f3nica de Madrid), Madrid Advanced Research Institutes \u201cIMDEAS\u201d (IMDEA \u2013 Alimentaci\u00f3n, IMDEA Nanociencia). Researchers will be selected through a transparent and international evaluation process taking into consideration the whole range of experience of the candidates.", "To": ["2021-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2015-FP - Marie Sk\u0142odowska-Curie Co-funding of regional, national and international programmes (COFUND-FP)"], "Funding_scheme": ["MSCA-COFUND-FP - Fellowship programmes"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["713366"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2015"]}, -{"Partners": ["UNIVERSIDAD DE SEVILLA", "UNIVERSIDAD DE SEVILLA"], "EU_Contribution": ["EUR 2 312 500"], "Project_Title": ["R-loops as a major modulator of transcription-associated recombination and chromatin dynamics"], "Total_Cost": ["EUR 2 312 500"], "Country": ["Spain", "Spain"], "Project_ACR": ["TARLOOP"], "Technology_Description": "Understanding the causes of genome instability, a condition linked to cancer and cancer-prone genetic diseases, is a major question in Molecular Biology and Biomedicine. Probably the most important natural cause of genome instability is transcription, which is known to induce both mutation and recombination from bacteria to human cells. Different studies suggest that transcription-associated recombination (TAR) is in large part due to collisions between transcription and replication, but increasing evidence indicate that R-loops, formed by a DNA-RNA hybrid and a displaced single-stranded DNA, may be a major determinant of genome instability. This is of particular relevance, provided our recent observation that tumor suppressor BRCA2 gene is involved in R-loop prevention/resolution and that, therefore, R-loops may represent a major potential source of tumorigenesis. The goal of this project is to understand the mechanisms of R-loop dynamics by identifying the functions and elements acting in cis and trans, that is, the DNA sequences and genes controlling R-loop formation and removal. The project will be based on a multidisciplinary approach using Saccharomyces cerevisiae and human cell lines. We plan: a) to identify the proteins and mechanism that actively works in the formation and prevention of intermediates responsible for R-loop-mediated TAR; b) to define the histone residues linked to R-loop formation and its role in chromatin dynamics, and c) to establish how the different trans and cis elements control genome-wide R-loop\u2013mediated genome instability whether or not in association with replication fork impairment, double-strand break accumulation, chromatin structure and mRNP biogenesis and export. The functional relevance of selected conserved genes will be validated in Caenorhabditis elegans as a model organism. The long-term objective of the proposal is to decipher the mechanisms by which R-loops modulate chromatin dynamics and genome instability.", "To": ["2020-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-12-01"], "Project_ID": ["669898"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 2 348 938"], "Project_Title": ["Duality in Formal Languages and Logic - a unifying approach to complexity and semantics"], "Total_Cost": ["EUR 2 348 938"], "Country": ["France", "France"], "Project_ACR": ["DuaLL"], "Technology_Description": "Dualities between algebraic and topological structure are pervasive in mathematics, and toggling back and forth between them has often been associated with important breakthroughs. The main objective of this project is to bring this important tool to bear on a number of subjects in theoretical computer science thereby advancing, systematising, and unifying them.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2015-09-01"], "Project_ID": ["670624"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["UNIVERSITE PARIS III SORBONNE NOUVELLE"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Francophone African and Caribbean Theaters"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["FACT"], "Technology_Description": "The cultural and artistic expressions of Black minorities are still unknown, devalued, and understudied in France today where exclusion and discrimination keep growing. Therefore it is urgent to analyze and recognize the work of African and Caribbean dramatists who embody the diversity and multiculturalism of our global contemporary world. The goal of FACT (Francophone African & Caribbean Theaters) is to revisit the history of Francophone Black theaters born out of the brutal encounter of Europe, Africa and the Americas, and to evaluate the effects of colonialism and postcolonialism on contemporary France. This colonial legacy is still denied today although being an integral part of the French national history. As a specialist of Caribbean theater, I will join the Theater studies Department at the University Sorbonne Nouvelle to collaborate with Professor Chalaye, specialist of African drama, to examine plays written by dramatists from Africa and the Caribbean from the 1960s to date. We intend to show that migrations that followed decolonization have transformed, nourished and enriched the French nation. We also want to challenge not only stereotypes and prejudices against Black minorities, but also the conception of a homogeneous unique French identity. FACT will contribute to make Francophone African and Caribbean drama more visible in the field by creating a database of texts and audio/videorecordings and by developing a postcolonial analysis of the materials. The outcome of FACT will create awareness among the general public of the reality of a multi-racial and multi-cultural nation born of a shared colonial history with the ultimate goal to encourage French and European citizens to lose their fears of the \u201cOther,\u201d to be opened to the difference, and to welcome and celebrate the diversity of Europe.", "To": ["2017-05-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-06-01"], "Project_ID": ["657877"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSIDAD AUTONOMA DE MADRID", "UNIVERSITY OF DURHAM", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "KARLSRUHER INSTITUT FUER TECHNOLOGIE", "UNIVERSITAT DE VALENCIA", "UNIVERSITAT ZURICH", "ISTITUTO NAZIONALE DI FISICA NUCLEARE", "UNIVERSITAT DE BARCELONA", "GEORG-AUGUST-UNIVERSITAT GOTTINGENSTIFTUNG OFFENTLICHEN RECHTS", "UNIVERSITY OF SOUTHAMPTON", "RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG"], "EU_Contribution": ["EUR 3 855 581,28"], "Project_Title": ["The Elusives Enterprise: Asymmetries of the Invisible Universe"], "Total_Cost": ["EUR 3 855 581,28"], "Country": ["Spain", "United Kingdom", "France", "Germany", "Germany", "Spain", "Switzerland", "Italy", "Spain", "Germany", "United Kingdom", "Germany"], "Project_ACR": ["ELUSIVES"], "Technology_Description": "NEUTRINOS and DARK MATTER (DM) are the most abundant and also the most elusive building-blocks of nature because of their tenuous couplings to the ordinary matter we are made of. Each particle has a mirror image with identical mass and opposite charge: its antiparticle. What is the essential nature of particles and antiparticles? This is a most fundamental open question in science. The laws of physics are almost -but not quite- symmetric for particles and antiparticles, and this could explain why the universe is made of matter, i.e. why we are here. Tiny differences detected in visible matter are largely insufficient, while an asymmetric behaviour of neutrinos or of DM may be the seed. In turn, the unnaturally symmetric behaviour of strong interactions points to a new particle, the axion, also a superb DM candidate. For the first time, the connection between these asymmetries in the visible and invisible world will be addressed. Very timely, an ambitious experimental search of asymmetric behaviour has been launched on neutrinos, axions and other DM, and the Higgs, with imminent major breakthroughs. The path to understand the Universe and build the New Standard Model must confront this problem. The mission of Elusives ITN is to form the new generation of researchers to accomplish this task, focusing on phenomenology with the necessary link to experiment. This is the first transnational such program, exploiting the capital investment in new experiments and overcoming the fragmentation of the research effort. ELUSIVES ITN is uniquely placed for it: * World-leadership in all relevant areas; * Multidisciplinarity; * Key theorists and experimentalists; * Outstanding training record; * CERN, Fermilab, SuperKamiokande and ADMX partners; * World leading cutting-edge research-related industry; * Highest professional beneficiary dissemination; * Top-quality expertise from emerging countries; * Optimal gender balance with over 50% female international leaders as coordinators.", "To": ["2020-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-04-01"], "Project_ID": ["674896"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["UNIVERSITEIT UTRECHT"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["Controlling micro- and nano-channel transport with selective solvation"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["COMNACTSS"], "Technology_Description": "The motivation for the COMNACTSS project comes from recent evidence that the selective solvation of ions in liquid mixtures has a dramatic influence on the interaction between colloids. Selective solvation introduces a new energy scale that is comparable with or often exceeds the thermal energy and this energy can be utilized for the dispersion of uncharged nano-particles, offering a polymer-and-surfactant-free pathway to nano-particle stabilization. The combination of a large energy-scale and chemical specificity offers a new handle for inducing liquid structuring and controlling flow at interfaces in confined and heterogeneous environments. I therefore propose to study theoretically, and by using molecular simulations, selective solvation in micro- and nano-fluidics. The research objectives are (i) gaining fundamental understanding of the dynamics of salt-containing mixtures in micro- and nano-fluidic channels and using it to investigate the transport of macromolecules through such channels. The use of salty mixtures will enable to greatly increase the transport of ions and macromolecules through pores, and the ability to control this transport, a key issue in science and technology. (ii) To uncover novel liquid-liquid interface destabilization mechanisms. The COMNACTSS project will advance the field of nanofluidics by introducing a new research paradigm which will enable new fundamental insights into the molecular organization and dynamics of complex fluids, with excellent potential to produce applications.", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["656327"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITEIT ANTWERPEN"], "EU_Contribution": ["EUR 172 800"], "Project_Title": ["Warmed Icelandic Soils, Lipids and Sequencing: towards a better understood climate proxy"], "Total_Cost": ["EUR 172 800"], "Country": ["Belgium"], "Project_ACR": ["WISLAS"], "Technology_Description": "The distribution of the soil bacterial membrane lipids \u201cbranched glycerol dialkyl glycerol tetraethers\u201d (brGDGTs) in geological records has been used to reconstruct palaeoclimatic conditions, specifically the mean annual air temperature and soil pH. However, the large error associated with the most recent brGDGT-based calibration, makes this method unsuitable for determining absolute temperatures. The fellow aims to perform geochemical and microbiological work that will result in the improvement of this palaeotemperature proxy. Firstly, an improved analytical method will be used, targeting not only fifteen brGDGTs that are currently used for palaeoclimate reconstructions, but including an additional fifteen brGDGT lipids, and a suite of precursors, whose diversity in soils is unstudied. This extended dataset will be measured in a well-studied, naturally (geothermally) warmed soil, linking the observed lipid distributions directly to the measured in-situ soil temperature (covering a 0-35\u00b0C gradient). Furthermore, the applicability of the novel temperature proxy proposed, will be tested in a well-studied dataset of European soils, covering a latitudinal temperature gradient. Although environmental studies point towards the Acidobacteria as the source organism, only one brGDGT has been found in an Acidobacterial culture so far and brGDGTs are still considered to be \u201corphan lipids\u201d. Using a novel approach to identify the source organism, the fellow proposes to study the microbial community using a next-generation sequencing method. Tracking the patterns in (Acido)bacterial distribution along a temperature gradient, will enable the fellow to ascertain if the changes in the brGDGT pool are caused by a shift in the microbial community, or are caused by phenotypic plasticity. This interdisciplinary project will improve the accuracy and interpretation of lipid-based palaeoclimate reconstructions and will extend the applicant\u2019s scientific experience and career perspectives.", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["707270"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSIDAD AUTONOMA DE MADRID", "UNIVERSIDAD AUTONOMA DE MADRID"], "EU_Contribution": ["EUR 1 987 750"], "Project_Title": ["Unconventional Bifunctional Catalysts"], "Total_Cost": ["EUR 1 987 750"], "Country": ["Spain", "Spain"], "Project_ACR": ["UNBICAT"], "Technology_Description": "The development of sustainable chemical processes is one of the most important features in modern chemistry. It has become a key research area worldwide providing solutions to important societal demands by optimizing the use of natural resources and minimizing waste and environmental impact. Among the relevant methods for achieving this goal, catalysis represents a key and central approach. Both Organocatalysis and Metal Catalysis have emerged as solutions to the problems in this context. In this field, the progress of a novel bifunctional organocatalyst that could increase the number of different activations, and therefore the synthesis of valuable enantio-enriched molecules, would be highly desirable. Especially important, but still unknown, are the bifunctional-catalysts based on a Neutral Coordinate Organocatalyst and Photo-Organocatalysts. This proposal aims to develop two new unconventional approaches for the synthesis of bifunctional organocatalysts.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["647550"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Control of the Homeostasis of Actin through Time: actin homeostasis during embryonic development by means of single-molecule imaging and simulation in C. elegans"], "Total_Cost": ["EUR 185 076"], "Country": ["France", "France"], "Project_ACR": ["CHAT"], "Technology_Description": "In embryonic cells, actomyosin forms a cortical reticulated gel that turns over rapidly, is weakly organized, and is composed of a variety of structures, with distinct architectures and dynamics, which are nucleated and elongated by different factors, and bind to specific sets of actin-binding proteins that modulate their dynamics. Understanding how actin is distributed between these structures is critical to understand the biology and mechanics of the actin cytoskeleton and therefore its role in processes ranging from morphogenesis and cell division to endocytosis and polarization.", "To": ["2017-03-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2015-04-01"], "Project_ID": ["661451"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITA CA' FOSCARI VENEZIA"], "EU_Contribution": ["EUR 250 518,60"], "Project_Title": ["Neurodidactics of Performing Arts: The Impact of Drama Teaching on Second Language Acquisition"], "Total_Cost": ["EUR 250 518,60"], "Country": ["Italy"], "Project_ACR": ["NPA"], "Technology_Description": "Since the 1990s, Educational Neuroscience has become an emerging field of research which studies cognitive brain functions (thinking, memory, attention, emotions) and interfaces with the educational environment with the aim of improving teaching and learning. Simultaneously, \"Drama Teaching\", a teaching methodology based on performing arts introduced in the 1970s, is now generating interest, especially in Foreign Language Learning. This research project will investigate aspects of cognition involved in the language learning process and it will analyse how Drama Teaching dynamics can impact language learning and proficiency. In order to define Drama Teaching as a methodology which involves the brain-mind-body dimension and fosters development of the learner as a whole person, a cognitive perspective will be adopted in relation to issues of a) embodied cognition, b) role of emotions in learning, c) impact of context and experience on learning d) cross-cultural identity process, development and awareness. Theoretical scientific investigation will be conducted on cognitive aspects relevant to learning, followed by the study and observation of dramatization practices. Development of curriculum and course implementation will follow. Particular attention will be given to the assessment of learning results and proficiency levels, as well as to the cognitive and emotional factors. The inter-disciplinary perspective adopted by this study is aimed at contributing to the debate on creative, interactive Foreign Language Education taking place in Europe and in the world. The scope is to contribute to the multi-disciplinary inquiries of Educational Neuroscience by elaborating a neuroscientifically grounded theory of Drama Teaching which gives educators guidelines to expand the range of teaching possibilities in accordance with the principles of Learning/Teaching of the \"Common European Framework of Reference for Languages\".", "To": ["2018-06-21, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-06-22"], "Project_ID": ["660495"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["HELMHOLTZ-ZENTRUM GEESTHACHT ZENTRUM FUR MATERIAL- UND KUSTENFORSCHUNG GMBH", "AIRBUS DEFENCE AND SPACE GMBH", "UNIVERSIDADE DE AVEIRO", "SMALLMATEK - SMALL MATERIALS AND TECHNOLOGIES LDA"], "EU_Contribution": ["EUR 648 000"], "Project_Title": ["MULTI-functional metallic SURFaces via active Layered Double Hydroxide treatments"], "Total_Cost": ["EUR 648 000"], "Country": ["Germany", "Germany", "Portugal", "Portugal"], "Project_ACR": ["MULTISURF"], "Technology_Description": "The main objective of the proposal is development of active multi-functional surfaces with high level of self-healing ability on the basis of Layered Double Hydroxide (LDH) structures formed on different industrially relevant metallic substrates. The main idea of the project is based on \u201csmart\u201d triggered release on demand for functional organic or inorganic anionic compounds intercalated into intergallery spaces of LDHs. The active functionality is achieved via controllable substrate-governed growth of LDH architectures on Al, Mg and Zn based alloys. The functional anions such as corrosion inhibitors, biocides, drugs, or hydrophobic agents are introduced into the intergallery spaces during the growth of LDH or upon a post-treatment stage. The release of the functional agents occurs only on demand when the respective functionality is triggered by the relevant external stimuli such as presence of anions or local pH change. ", "To": ["2018-12-31, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["645676"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["POLITECNICO DI MILANO", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "UNIVERSIDAD DE SEVILLA"], "EU_Contribution": ["EUR 450 000"], "Project_Title": ["Sustainable Design and Management of Industrial Assets through Total Value and Cost of Ownership"], "Total_Cost": ["EUR 450 000"], "Country": ["Italy", "United Kingdom", "Spain"], "Project_ACR": ["Sustain-Owner"], "Technology_Description": "SoThe project will examine the potential of Total Value and Cost of Ownership (TVO, TCO) for supporting the design and through-life management of industrial assets.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-01-01"], "Project_ID": ["645733"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["UNIVERSITAET POTSDAM", "UNIVERSITE PARIS DESCARTES", "JYVASKYLAN YLIOPISTO", "NIRX MEDIZINTECHNIK GMBH", "UNIVERSIDAD POMPEU FABRA"], "EU_Contribution": ["EUR 3 848 639,76"], "Project_Title": ["Understanding and predicting developmental language abilities anddisorders in multilingual Europe"], "Total_Cost": ["EUR 3 848 639,76"], "Country": ["Germany", "France", "Finland", "Germany", "Spain"], "Project_ACR": ["PREDICTABLE"], "Technology_Description": "PredictAble aims to train a new generation of young scientists at the crossroads between academic research, technological development in the private sector and clinical practice to pioneer an interdisciplinary approach to language related developmental disorders, like specific language impairment (SLI) and developmental dyslexia (DD). The innovative and timely research program will enhance the understanding of the cognitive mechanisms that underlie developmental disorders of spoken and written language by pooling international experts from academia and the private sector. For the first time, PredictAble applies a truly multidisciplinary and cross-linguistic perspective with a unique and novel combination of cutting-edge approaches and techniques for studying mono- and bilingual children. Thus, PredictAble will provide young researchers with an excellent foundation for making scientific progress in this area, in collaboration with technology development and the transfer of research outcomes to applicants in the private sector and the health sector/clinical practice. Highly recognized experts in the area of language acquisition in very young mono- and bilingual children will work together on the acquisition of spoken and written language in a cross-linguistic approach. The complementarity of the different languages in PredictAble will make it possible to identify language-specific and cross-linguistically valid effects. In cooperation with technological partners from the private sector, PredictAble will optimize recently developed technologies in the area of developmental cognitive neuroscience to render them suitable for use with very young children and as diagnostic tools to detect early risks for language-related impairments.", "To": ["2019-02-28, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2015-03-01"], "Project_ID": ["641858"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["MUSEUM NATIONAL D'HISTOIRE NATURELLE", "UNIVERSITAT AUTONOMA DE BARCELONA", "CERDAN INGENIEROS S.L.", "MARTIN LOYER", "UNIVERSITE D'AIX MARSEILLE", "UNIVERSITE D'AVIGNON ET DES PAYS DE VAUCLUSE", "UNIVERSITE PARIS DIDEROT - PARIS 7", "UNIVERSITE PARIS III SORBONNE NOUVELLE", "CABILDO INSULAR DE LANZAROTE", "ASSOCIACIO GEOPARC CONCA DE TREMP -MONTSEC"], "EU_Contribution": ["EUR 1 296 000"], "Project_Title": ["Geoparks: Heritage, Education and Sustainable Development - an Innovative Methodology for Southern Countries. Case Study in Morocco (Atlas Mountains, Marrakech)"], "Total_Cost": ["EUR 1 296 000"], "Country": ["France", "Spain", "Spain", "France", "France", "France", "France", "France", "Spain", "Spain"], "Project_ACR": ["Geopark"], "Technology_Description": "According to the Charter of the European Geoparks Network adopted in Greece the 5th June of 2000, a European Geopark \u201cis a territory which includes a particular geological heritage and a sustainable territorial development strategy supported by a European programme to promote development. [\u2026]\u201d.These territories have been labelled regarding their geological, cultural and ecological heritage - since the early 2000s this Label knows a growing success among European countries, particularly in the West (France, Germany, Italy, Spain). In 2013, 54 European Geoparks received the precious label. This international recognition by UNESCO attracts Southern countries to implement development strategies in line with the recommendations of good-practices management oriented by international organizations. Indeed, UNESCO takes into account a plurality of selective criteria such as a remarkable heritage (geology, archaeology, biodiversity, cultural), citizen participation, sustainable regional economic development plan, heritage and socio-economic values for local populations, etc. to proceed to the inscription process. It is based on an integrated and sustainable management & conservation strategy of natural and cultural heritage from an interdisciplinary approach (Humanities and Life & Earth Sciences) in consultation with local stakeholders (local communities, universities and civil society). Currently, there is no \u201cGeopark methodology\u201d adapted to the South. Thus, the GEOPARK project aims to study potential and compared areas (EU/Africa) with remarkable geological, ecological, social and cultural heritage. One located in Central Catalunia (Spain) and the other in the Zat Valley (Morocco) - Marrakech. Endowed with varied skills in Humanities and Life and Earth Sciences, GEOPARK project partners (public, private) propose to study biodiversity, geology, prehistory, social aspects, heritage, tourism as a geopark based on empirical surveys, field collecting data and shared experience.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Other"], "From": ["2015-01-01"], "Project_ID": ["644015"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER", "WIRTSCHAFTSUNIVERSITAT WIEN", "UNIVERSIDAD DE SEVILLA", "TECHNISCHE UNIVERSITEIT EINDHOVEN", "PICTURE GMBH", "CUPENYA BV"], "EU_Contribution": ["EUR 855 000"], "Project_Title": ["Propelling Business Process Management by Research and Innovation Staff Exchange"], "Total_Cost": ["EUR 1 273 500"], "Country": ["Germany", "Austria", "Spain", "Netherlands", "Germany", "Netherlands"], "Project_ACR": ["RISE_BPM"], "Technology_Description": "RISE_BPM networks world-leading research institutions and corporate innovators to develop new horizons for Business Process Management (BPM). BPM is a boundary-spanning discipline focused on division and re-integration of day-to-day work in organisations and on analysis of process data for organisational decision-making. Recent break-through innovations in Social Computing, Smart Devices, Real-Time Computing, and Big Data Technology create a strong impetus for propelling BPM into a pervasive corporate topic that enables design of entirely new products and services.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-05-01"], "Project_ID": ["645751"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["UNIVERSIDAD AUTONOMA DE MADRID", "NARODOWE CENTRUM BADAN JADROWYCH", "POLITECHNIKA WARSZAWSKA"], "EU_Contribution": ["EUR 310 500"], "Project_Title": ["Super-Kamiokande plus"], "Total_Cost": ["EUR 310 500"], "Country": ["Spain", "Poland", "Poland"], "Project_ACR": ["SKPLUS"], "Technology_Description": "This proposal is a part of ongoing global efforts to understand the most fundamental elements of matter and their interactions. We aim to investigate neutrino interactions using the existing experimental facility in Japan, the Super-Kamiokande (SK) detector located in the Kamioka Observatory (Gifu Prefecture) and owned by the Partner of this Project: the Institute for Cosmic Ray Research of the University of Tokyo. ", "To": ["2018-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2014-12-01"], "Project_ID": ["641540"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "JRC -JOINT RESEARCH CENTRE- EUROPEAN COMMISSION", "EUROPEAN RESEARCH SERVICES GMBH", "LEIDOS BIOMEDICAL RESEARCH INC", "THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN", "STIFTELSEN SINTEF", "THE UNIVERSITY OF LIVERPOOL", "EIDGENOSSISCHE MATERIALPRUFUNGS- UND FORSCHUNGSANSTALT", "GESELLSCHAFT FUR BIOANALYTIK MUNSTER EV"], "EU_Contribution": ["EUR 4 995 181"], "Project_Title": ["European Nanomedicine Characterization Laboratory"], "Total_Cost": ["EUR 5 627 303,50"], "Country": ["France", "Belgium", "Germany", "United States", "Ireland", "Norway", "United Kingdom", "Switzerland", "Germany"], "Project_ACR": ["EUNCL"], "Technology_Description": "In order to accelerate the development of the nanomedicine business in Europe, EU-NCL interconnects 8 European and 1 American key reference facilities with a proven expertise in physical, chemical, in vitro and in vivo biological characterisation of nanoparticles for medical applications. The objective is to reach a level of international excellence in nanomedicine characterization for all medical indication, and make it accessible to all organisations developing candidate nanomedicines prior to their submission to the regulatory agencies in order to get the approval for clinical trials and later the marketing authorization. EU-NCL is partnered with the sole international reference facility namely the Nanotechnology Characterisation Lab of the USA to get a faster international harmonization of analytical protocols. EU-NCL is closely connected to national medicine agencies and to the European Medicine Agency in order to permanently adapt its analytical services to the need and requests of the regulators. EU-NCL is designed, organized and operated according to the highest EU regulatory and quality standards in order to provide a full analytical cascade of 42 assays. Within EU-NCL, 6 analytical facilities will offer a Trans National Access to their existing analytical services but they will also develop new or improved analytical assays under the Joint Research Activities in order to keep EU-NCL at the cutting edge of the nanomedicine characterisation. A complementary set of networking activities will make EU-NCL able to deliver to the European academic or industrial scientists the best analytical services they dramatically require for accelerating the industrial development of their candidate nanomedicines. An exploitation and business plan will be proposed at the end of the project in order to submit a sustainable development plan beyond the initial period of 4 years.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["INFRAIA-1-2014-2015 - Integrating and opening existing national and regional research infrastructures of European interest"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2015-05-01"], "Project_ID": ["654190"], "Call_for_Proposal": ["H2020-INFRAIA-2014-2015"]}, -{"Partners": ["POLITECNICO DI MILANO", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "UNIVERSITEIT GENT", "TECHNISCHE UNIVERSITEIT EINDHOVEN", "SORIN GROUP ITALIA SRL", "PHILIPS MEDICAL SYSTEMS NEDERLAND BV", "MATERIALISE NV", "BIOENGINEERING LABORATORIES", "LIFETEC GROUP BV", "FEOPS NV"], "EU_Contribution": ["EUR 3 835 204,56"], "Project_Title": ["MUltiSectoral Integrative approaches to CArdiac care"], "Total_Cost": ["EUR 3 835 204,56"], "Country": ["Italy", "United Kingdom", "Belgium", "Netherlands", "Italy", "Netherlands", "Belgium", "Italy", "Netherlands", "Belgium"], "Project_ACR": ["MUSICARE"], "Technology_Description": "MUltiSectoral Integrative approaches to CArdiac care \u2013 MUSICARE - is proposed by a team of universities, companies and hospitals from 4 EU countries (Italy, United Kingdom, The Netherlands, Belgium). The main scope of MUSICACARE is to structure a new trans-sectoral and multidisciplinary network capable of developing research and technology with no barriers between academia, industries and clinicians in the cardiac arena, and of shaping young researchers with a novel and truly multidisciplinary mindset, capable of developing clinical- and business-oriented technology including tools for the advancement of base knowledge. MUSICARE activity will impact on the field of cardiac surgery in three ways: ", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["642458"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["UNIVERSIDAD AUTONOMA DE MADRID", "UNIVERSITY OF DURHAM", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH", "UNIVERSITAT DE VALENCIA", "UNIVERSITAT ZURICH", "ISTITUTO NAZIONALE DI FISICA NUCLEARE", "UNIVERSITAT DE BARCELONA", "GEORG-AUGUST-UNIVERSITAT GOTTINGENSTIFTUNG OFFENTLICHEN RECHTS", "UNIVERSITY OF SOUTHAMPTON", "RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 2 070 000"], "Project_Title": ["InvisiblesPlus"], "Total_Cost": ["EUR 2 322 000"], "Country": ["Spain", "United Kingdom", "France", "Germany", "Switzerland", "Spain", "Switzerland", "Italy", "Spain", "Germany", "United Kingdom", "Germany", "Spain"], "Project_ACR": ["InvisiblesPlus"], "Technology_Description": "NEUTRINOS (Ns) and DARK MATTER (DM) are the most abundant particles in the universe. Their couplings to ordinary matter are so tenuous that they remained undiscovered -invisible- until very recently. N masses and DM constitute the first evidence ever of physics beyond the Standard Model of particle physics. The path to build the New Standard Model must confront the fundamental nature of the particles in the invisible sector at large. Furthermore, for each particle there is a mirror image with identical mass and opposite charge(s): its antiparticle. The laws of physics are almost particle-antiparticle symmetric: an asymmetry in Ns and/or DM properties may be the required seed that explains why the universe is made of matter and not antimatter, i.e. how come we are here, a fact unexplained by standard physics. In turn, the unnaturally symmetric behavior of strong interactions points to a new particle, the axion, a superb dark matter candidate. Very timely, an ambitious international experimental search has been launched on Ns, axions, other DM and Higgs physics with major breakthroughs expected soon.", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2016-02-01"], "Project_ID": ["690575"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU", "NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO", "NATURAL ENVIRONMENT RESEARCH COUNCIL", "STIFTELSEN SINTEF", "FUNDACION CIUDAD DE LA ENERGIA", "PANSTWOWY INSTYTUT GEOLOGICZNY - PANSTWOWY INSTYTUT BADAWCZY", "ISTITUTO NAZIONALE DI OCEANOGRAFIA E DI GEOFISICA SPERIMENTALE", "SINTEF ENERGI AS", "ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS", "SOTACARBO - SOCIETA TECNOLOGIE AVANZATE CARBONE SPA.", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "GLOWNY INSTYTUT GORNICTWA", "SINTEF PETROLEUM AS", "BUREAU DE RECHERCHES GEOLOGIQUES ET MINIERES"], "EU_Contribution": ["EUR 3 252 279"], "Project_Title": ["European Carbon Dioxide Capture and Storage Laboratory Infrastructure"], "Total_Cost": ["EUR 3 252 279,60"], "Country": ["Norway", "Netherlands", "United Kingdom", "Norway", "Spain", "Poland", "Italy", "Norway", "Greece", "Italy", "Switzerland", "Poland", "Norway", "France"], "Project_ACR": ["ECCSEL"], "Technology_Description": "ECCSEL aims at gaining recognition as a world-class research infrastructure based within leading European Carbon Capture and Storage (CCS) institutions and knowledge centres. It will be due for registration in 2015, forming a legal entity allocating efforts and resources to selected scientific and technological aspects of the CCS chain. ", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["INFRADEV-3-2015 - Individual implementation and operation of ESFRI projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations"], "From": ["2015-09-01"], "Project_ID": ["675206"], "Call_for_Proposal": ["H2020-INFRADEV-1-2015-1"]}, -{"Partners": ["UNIVERSITAET POTSDAM", "ENZA ZADEN RESEARCH & DEVELOPMENT BV", "BIOATLANTIS"], "EU_Contribution": ["EUR 1 268 698,32"], "Project_Title": ["Genetic and molecular priming approaches to increase crop strength and stress tolerance"], "Total_Cost": ["EUR 1 268 698,32"], "Country": ["Germany", "Netherlands", "Ireland"], "Project_ACR": ["CropStrengthen"], "Technology_Description": "The project provides advanced systems biology training for 5 ESRs who will develop novel methods for increasing crop strength and resistance to stress by alternative genetic and genomic, non-GMO, technologies: (1) Selecting allelic variants of a novel gene identified by members of the consortium which regulates oxidative and abiotic stress tolerance and (2) Molecular priming by biostimulants or low doses of H2O2 to induce stress-protective mechanisms in crops. This dual approach will meet the growing EU push towards secure, sustainable and safe means of food production (Dir.2009/128/EC & EU Reg. EC/178/2002). The genetic approaches are combined with high-throughput technologies for transcriptome, metabolome, and phenotypic analyses, combined with advanced bioinformatics. Both approaches to increasing crop yield are growing in importance, with the biostimulants industry expected to reach $2.2B globally by 2018. Equipping ESRs with these skills will enable them to develop their research careers in academia or industry. Training will be conducted at the University of Potsdam (UP, Coordinator), Germany, and two companies: BioAtlantis (BA), Ireland, and Enza Zaden (EZ), The Netherlands. Prof. B. Mueller-Roeber (UP) has extensive research management and teaching experience and will supervise the ESRs as PhD students. BA is internationally recognized for producing innovative biostimulants and has 3 patents filed, while EZ is among the top ten in vegetable breeding worldwide. All partners have experience in coordination and participation in EU FP7 projects. The expected results will increase our understanding of the molecular basis of stress tolerance and provide two alternative strategies for crop improvement and increasing food production. BA and EZ will ensure rapid dissemination of applied research to end users.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-EID - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-EID)"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["642901"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["CLARIN ERIC", "UNIVERZITA KARLOVA", "EBERHARD KARLS UNIVERSITAET TUEBINGEN", "KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 1 495 300"], "Project_Title": ["Strengthening the CLARIN Infrastructure."], "Total_Cost": ["EUR 1 495 300"], "Country": ["Netherlands", "Czech Republic", "Germany", "Denmark"], "Project_ACR": ["CLARIN-PLUS"], "Technology_Description": "CLARIN, the Common Language Resource and Technology Research Infrastructure, has gained force and momentum over the last 10 years. It is being constructed as a distributed e-infrastructure for the Humanities and Social Sciences to enable sustainable access, exploitation and integration of Europe\u2019s vast amount of language-based data and related technology. ", "To": ["2017-12-31, closed project"], "Meta": [""], "Topic_s": ["INFRADEV-3-2015 - Individual implementation and operation of ESFRI projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Netherlands"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["676529"], "Call_for_Proposal": ["H2020-INFRADEV-1-2015-1"]}, -{"Partners": ["PANEPISTIMIO KRITIS", "TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY", "TECHNISCHE UNIVERSITAET WIEN"], "EU_Contribution": ["EUR 648 000"], "Project_Title": ["Non-Hermitian Quantum Wave Engineering"], "Total_Cost": ["EUR 648 000"], "Country": ["Greece", "Israel", "Austria"], "Project_ACR": ["NHQWAVE"], "Technology_Description": "The concept of parity-time (PT)-symmetry is extensively studied now owing to the ubiquitous applications within the fields of optics, photonics, and plasmonics. Among the many recent developments in PT-systems, the application of pseudo-Hermitian ideas not only promises a new generation of photonic and plasmonic components such as lasers, spasers, modulators, waveguides, and detectors, but also opens new avenues for innovative electronics architectures for signal manipulation from integrated circuits to antenna arrays, and allows for direct contact with cutting edge technological problems appearing in (nano)-antenna theory, split-ring resonator arrays, and metamaterials. More recently, potential applications have also been proposed in connection with magnetic and acoustic structures. ", "To": ["2020-02-29, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Greece"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["691209"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["UNIVERSIDAD AUTONOMA DE MADRID", "KATHOLIEKE UNIVERSITEIT LEUVEN", "RIJKSUNIVERSITEIT GRONINGEN", "UNIVERSITE PAUL SABATIER TOULOUSE III", "UNIVERSITA DEGLI STUDI DI PERUGIA", "UNIVERSITAT WIEN", "UNIVERSITAT DE BARCELONA", "UNIVERSITA DI PISA", "UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6", "UNIVERSIDADE DO PORTO", "UNIVERSITAT DE VALENCIA", "UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA"], "EU_Contribution": ["EUR 3 785 867,52"], "Project_Title": ["Theoretical Chemistry and Computational Modelling"], "Total_Cost": ["EUR 3 785 867,52"], "Country": ["Spain", "Belgium", "Netherlands", "France", "Italy", "Austria", "Spain", "Italy", "France", "Portugal", "Spain", "Spain"], "Project_ACR": ["TCCM"], "Technology_Description": "Theoretical Chemistry and Computational Modelling (TCCM) is emerging as a powerful tool to help in the rational design of new products and materials for pharmaceutical, chemical, energy, computer, and new-materials industries. To achieve this goal, it is necessary to go beyond the traditional electronic structure studies, and merge complementary techniques that are normally not available at a single research group. The research programme of the TCCM-EJD aims at applying computational modelling to problems demanded by the industry and with high societal relevance, namely Materials with special properties, Biomolecules for new therapies and Energy storage. The objective of the Joint Doctorate is to prepare future research leaders, able to develop and use multidisciplinary computational techniques (methods and software), with solid communication skills, with many contacts established through the intensive relationship with worldwide leading researchers of 12 European universities and 14 additional partners, including 7 industrial and spin-off companies. A Joint Doctorate in TCCM is already operative since 2011, based on a fully participative scientific discussion and assessment of all research projects with a clear interdisciplinary character and the direct participation of the non-academic sector. The training programme puts the emphasis in common training, including 3 annual International Workshops, 3 schools on High Performance Computing and 3 tutorials in new computer codes. Career development opportunities are enhanced with regular inter-sectoral activities, transferable skill education and career coaching.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-EJD - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-EJD)"], "Funding_scheme": ["MSCA-ITN-EJD - European Joint Doctorates"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-01-01"], "Project_ID": ["642294"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["COMUNE DI GENOVA", "ASSOCIAZIONE FESTIVAL DELLA SCIENZA", "CONSIGLIO NAZIONALE DELLE RICERCHE", "FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA", "UNIVERSITA DEGLI STUDI DI GENOVA", "SIIT SOCIETA CONSORTILE PER AZIONI SIGLABILE SIIT SCPA", "IL GIARDINO LETTERARIO DELFINO ASSOCIAZIONE", "DISTRETTO LIGURE DELLE TECNOLOGIE MARINE SCRL"], "EU_Contribution": ["EUR 160 000"], "Project_Title": ["Party do not stop. Having fun with researchers"], "Total_Cost": ["EUR 160 531,25"], "Country": ["Italy", "Italy", "Italy", "Italy", "Italy", "Italy", "Italy", "Italy"], "Project_ACR": ["Party do not stop"], "Technology_Description": "\"\"\"Party do not stop\"\" includes the proposal of two editions of the Researchers' Night to be carried out in Liguria in 2014 and 2015. ", "To": ["2015-12-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-NIGHT-2014 - European Researchers' Night (NIGHT)"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Italy"], "Activity": ["Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Other", "Research Organisations", "Research Organisations", "Chiara Andreoli", "Tel.: +3901071781854", "Fax: +39 010 7170817", "Higher or Secondary Education Establishments", "Other", "Other", "Research Organisations"], "From": ["2014-05-01"], "Project_ID": ["633306"], "Call_for_Proposal": ["H2020-MSCA-NIGHT-2014"]}, -{"Partners": ["UNIVERSITAT AUTONOMA DE BARCELONA", "UNIVERSITAT DE BARCELONA", "UNIVERSIDAD DE SEVILLA", "MIDDLESEX UNIVERSITY HIGHER EDUCATION CORPORATION", "TAMPEREEN YLIOPISTO", "UNIVERSIDADE DA CORUNA", "UNIVERSIDAD DE LA LAGUNA", "UNIVERSITA DEGLI STUDI DI MILANO", "UNIVERSITA DELLA CALABRIA", "UNIVERSITE DE TOULOUSE II - LE MIRAIL"], "EU_Contribution": ["EUR 2 344 500"], "Project_Title": ["Global trends in social inequalities in Europe and Latin America and exploring innovative ways to reduce them through life, occupational and educational trajectories research to face uncertainty"], "Total_Cost": ["EUR 2 344 500"], "Country": ["Spain", "Spain", "Spain", "United Kingdom", "Finland", "Spain", "Spain", "Italy", "Italy", "France"], "Project_ACR": ["INCASI"], "Technology_Description": "The overall aim of this project is to create an International Network for Comparative Analysis of Social Inequalities (INCASI) with 19 universities, 10 from Europe and 9 from Latin America. The purpose is to conduct comparative research in the area of social inequalities. Through this network we hope to foster a space for collective reflection and the development of synergies between network partners that allow us to undertake innovative studies whose outputs have an impact on academic and policy debates on the subject. The project will also contribute to informing the design of public policies to tackle social inequalities. In so doing, we aim to contribute innovative solutions that improve citizens\u2019 living standards, reduce social inequalities and promote social justice. This is in line with Horizon 2020\u2019s objectives.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["691004"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "POLO D'INNOVAZIONE DI GENOMICA, GENETICA E BIOLOGIA SCARL", "UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA", "UNIVERSITA DEGLI STUDI DI PERUGIA", "MICROTEST MATRICES LTD", "GENIALIS D.O.O"], "EU_Contribution": ["EUR 1 053 000"], "Project_Title": ["Monitor population immunity against vaccine preventable diseases"], "Total_Cost": ["EUR 1 053 000"], "Country": ["United Kingdom", "Italy", "Italy", "Italy", "United Kingdom", "Slovenia"], "Project_ACR": ["Vaccinesurvey"], "Technology_Description": "In the recent years an unprecedented effort has been made to increase the rates of childhood immunization in resource poor countries. This has translated into an increased number of children receiving vaccines and a parallel decrease in the rate of illnesses from vaccine preventable diseases. However, in some regions it has proven difficult to achieve optimal levels of immunization mainly because of issues concerning communication, management and poor utilization of resources. Recent studies have questioned the validity of available vaccine coverage data and the way they are collected. Currently, both the progress of the vaccination programs and indirectly the level of protection in a population are inferred on the basis of administrative records. This largely unverified information is also utilized as performance indicator to allocate funds from government and donor agencies. Such self-certification practice does not incentivize the optimization of resources while it has been increasingly questioned in terms of its validity and integrity. We propose to develop and validate an innovative technical solution based on an assay system that integrates multiplex capability and analytical performance, to simultaneously quantify antibody levels against the major vaccine components, with both automation and wireless connectivity to produce spatial-temporal co-ordinates of individual determinations. The multiplex capability will facilitate the analysis of cross coverage monitoring while generating reactivity profiles against the different vaccine components to discriminate vaccinated versus infected individuals. Spatial temporal co-ordinates of assay results will be used to generate interactive data sets for modeling changes in the age-specific risk of infection and the risk of outbreaks. The proposed system represents a formidable tool of unprecedented power to monitor the progress of different vaccination programs and experimentally validate record-based coverage data.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["645754"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "CHALMERS TEKNISKA HOEGSKOLA AB", "UNIVERSIDAD COMPLUTENSE DE MADRID", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V."], "EU_Contribution": ["EUR 2 036 981,25"], "Project_Title": ["CAlcium Rechargeable BAttery Technology"], "Total_Cost": ["EUR 2 036 981,25"], "Country": ["Spain", "Sweden", "Spain", "Germany"], "Project_ACR": ["CARBAT"], "Technology_Description": "\"We propose calcium based rechargeable batteries to be a FET helping to solve some of the Grand Challenges our modern society is facing: pollution, oil-dependency, and climate change. Today transportation contributes to >25% of the total CO2-emissions globally and while electrification of the sector is on-going still <1% of cars run on batteries \u2013 mainly due to issues of cost and driving ranges feasible (energy density limited). While the cost of the totally dominant Li-ion battery (LIB) technology has been reduced by an impressive 50%(!) the last decade, LIBs are slowly reaching their fundamental limits in terms of energy density. Furthermore, the risk of limited lithium supply and associated cost increases cannot be ignored. Therefore, new sustainable battery chemistries must be developed and Next Generation Batteries was indeed ranked as the #2 game-changing technology by the World Economic Forum in Davos 2016. ", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-01-2016-2017 - FET-Open research and innovation actions"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2017-10-01"], "Project_ID": ["766617"], "Call_for_Proposal": ["H2020-FETOPEN-1-2016-2017"]}, -{"Partners": ["DESCUBRE - FUNDACION ANDALUZA PARA LA DIVULGACION DE LA INNOVACION Y EL CONOCIMIENTO", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "UNIVERSIDAD DE MALAGA", "UNIVERSIDAD DE ALMERIA", "UNIVERSIDAD DE GRANADA", "UNIVERSIDAD DE CADIZ", "UNIVERSIDAD DE CORDOBA", "INSTITUTO MUNICIPAL DE GESTION MEDIOAMBIENTAL - JARDIN BOTANICO DE CORDOBA", "UNIVERSIDAD DE SEVILLA", "UNIVERSIDAD DE JAEN", "UNIVERSIDAD PABLO DE OLAVIDE", "AYUNTAMIENTO DE MALAGA", "CONSEJERIA DE ECONOMIA INNOVACION CIENCIA Y EMPLEO", "INSTITUTO ANDALUZ DE INVESTIGACIONY FORMACION AGRARIA PESQUERA ALIMENTARIA Y DE LA PRODUCCION ECOLOGICA"], "EU_Contribution": ["EUR 159 000"], "Project_Title": ["RESEARCHERS SQUARE"], "Total_Cost": ["EUR 422 423,75"], "Country": ["Spain", "Spain", "Spain", "Spain", "Spain", "Spain", "Spain", "Spain", "Spain", "Spain", "Spain", "Spain", "Spain", "Spain"], "Project_ACR": ["RESSQUA"], "Technology_Description": "\u2018Researchers Square\u2019 is designed to increase the awareness of research as a solution to the numerous challenges faced by people all around the world and mainly in Europe. The idea of the project, \u2018Better Living through Science: from Social Sciences and Humanities to Maths and Technology\u2019, has been conceived in times of crisis, a moment where becomes clearer that we must join efforts to find innovative solutions to encourage young people\u2019s interest in research. It responds also to the challenge of building bridges between researchers and general public, showing that science could give answer to the societal challenges that we are facing in Europe.", "To": ["2015-11-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-NIGHT-2014 - European Researchers' Night (NIGHT)"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Spain"], "Activity": ["Other", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations"], "From": ["2014-04-01"], "Project_ID": ["633304"], "Call_for_Proposal": ["H2020-MSCA-NIGHT-2014"]}, -{"Partners": ["FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS", "BEN-GURION UNIVERSITY OF THE NEGEV", "ADVANCED WAVE SENSORS S.L.", "PANEPISTIMIO KRITIS", "JOBST TECHNOLOGIES GMBH", "UNIVERSIDAD AUTONOMA DE MADRID", "INSTITUT CURIE"], "EU_Contribution": ["EUR 3 411 478,75"], "Project_Title": ["Capturing non-Amplified Tumor Circulating DNA with Ultrasound Hydrodynamics"], "Total_Cost": ["EUR 3 412 478,75"], "Country": ["Greece", "Israel", "Spain", "Greece", "Germany", "Spain", "France"], "Project_ACR": ["CATCH-U-DNA"], "Technology_Description": "The project suggests replacing the labor-intensive, occasionally biased and costly PCR method currently used for the detection of genetic markers with a simple, non-PCR based DNA quantification method. The suggested system will exploit the ability of acoustic waves to probe the hydrodynamic shape of surface-bound molecules, rather than mass. The scientific challenge to be addressed is to push the limit of detection to the zM range obviating the need to use a polymerase for DNA amplification. The technological challenge is to fabricate ultra sensitive acoustic devices and after capturing with high efficiency very low numbers of DNA present in a complex medium detecting them on the device surface. These ambitious goals will be achieved by developing novel probes and nanoparticles of tailor-made sizes and shapes for enhanced acoustic response; exploiting high frequency acoustic devices up to the GHz range; and, employing magnetic beads with microfluidics for specific target-capturing and enrichment. The proof-of-principle will be demonstrated during the detection of circulating-tumor DNA (ctDNA), currently an area perceived by cancer researchers as the \u201cHoly Grail\u201d of future cancer diagnosis, prognosis and treatment. We intend to validate our integrated acoustic platform towards the detection of common mutations occurring in colorectal and lung cancers, i.e., KRAS, EGFR and BRAF in serum. We anticipate that the \u201cCATCH-U-DNA\u201d concept will set the foundations for a simpler, more sensitive and affordable diagnostic method, from which patients in both the developed and developing countries will greatly benefit.", "To": ["2020-05-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-01-2016-2017 - FET-Open research and innovation actions"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Greece"], "Activity": ["Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2017-06-01"], "Project_ID": ["737212"], "Call_for_Proposal": ["H2020-FETOPEN-1-2016-2017"]}, -{"Partners": ["JOHN INNES CENTRE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Computational Prediction and Validation of RNA thermometer at transcriptome-wide scale in living cell"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ComPreValRther"], "Technology_Description": "Temperature is crucial to plants\u2019 growth and development. The cold and heat stresses may drastically inhibit plant growth and cause yield losses in crops. Understanding the temperature responding mechanism is crucial to adapt the crops to withstand extreme temperature changes caused by global warming. Among other temperature regulation mechanism, RNA thermometers (RNATs) can instantaneously respond to temperature shift and directly control translational efficiency therefore protein abundance. To date, no RNAT has been identified in plant mainly due to the fact that instead of sequence level conservation, RNATs only have structure level conservation; also because in-vivo RNA structure probing used to be technically challenging. The host lab has developed a powerful platform for in vivo RNA secondary structure probing at both targeted individual RNA and genome-wide scale. This proposed study aims to globally identify RNA thermometers in plants for the first time, and to quantitatively elucidate the role of RNA structure in the post-transcriptional regulation of gene expression in response to temperature. I will measure the alteration of in vivo RNA structural features in Arabidopsis thaliana under different temperature regime. Additionally, Ribosome profiling data and RNA-Seq data will be combined to study the translation efficiency under the corresponding temperature. Together with the identified significantly changed RNA structure elements, we will be able to determine the putative RNAT. Finally, I will validate the predicted RNATs through studying nature variations. I will perform in-vivo RNA structure probing and determine whether the identified single nucleotide variations (SNV) will have significant effects on temperature-regulatory elements. Besides the potential for crop improvement, our approach to globally measure RNA secondary structure and the corresponding translation efficiency will be easily applied to other organisms and various environmental stimuli.", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations"], "From": ["2017-08-01"], "Project_ID": ["753958"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT", "UNIVERSITE DE BRETAGNE OCCIDENTALE", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSITE DE NANTES", "FUNDACAO GASPAR FRUTUOSO", "FCIENCIAS.ID - ASSOCIACAO PARA A INVESTIGACAO E DESENVOLVIMENTO DE CIENCIAS", "WAGENINGEN UNIVERSITY", "UNIVERSIDAD DE SEVILLA", "LEIBNIZ-ZENTRUM FUER MARINE TROPENOEKOLOGIE (ZMT) GMBH", "TERRA MARIS", "CREOCEAN"], "EU_Contribution": ["EUR 1 557 000"], "Project_Title": ["Planning in A liquiD worlD with tropicaL StakEs: solutions from an EU-Africa-Brazil perspective"], "Total_Cost": ["EUR 1 723 500"], "Country": ["France", "France", "France", "France", "Portugal", "Portugal", "Netherlands", "Spain", "Germany", "France", "France"], "Project_ACR": ["PADDLE"], "Technology_Description": "Marine environments are subject to growing pressures as traffic, increasing demand and changing land-use of coastal areas, seabed exploitation, dredging or mining, fishing, tourism, development of renewable energies, etc. Sustainably managed oceans and seas can contribute to economic growth and employment, and will allow the international community to meet its global targets, including the reduction of poverty and hunger as detailed in the global 2030 Sustainable Development Agenda. Thus, marine environments are considered opportunities for future growth not only in Europe, but also in bordering marine areas like the tropical Atlantic.", "To": ["2021-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-07-01"], "Project_ID": ["734271"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI PERUGIA", "POLO D'INNOVAZIONE DI GENOMICA, GENETICA E BIOLOGIA SCARL", "INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT", "UNIVERSITA DEGLI STUDI DI MILANO", "CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TECNICAS (CONICET)", "CENTRO DE INVESTIGACION Y DE ESTUDIOS AVANZADOS DEL INSTITUTO POLITECNICO NACIONAL"], "EU_Contribution": ["EUR 738 000"], "Project_Title": ["Harnessing Plant Reproduction for Crop Improvement"], "Total_Cost": ["EUR 738 000"], "Country": ["Italy", "Italy", "France", "Italy", "Argentina", "Mexico"], "Project_ACR": ["PROCROP"], "Technology_Description": "Increased crop productivity through genetic improvement of plants has significantly impacted world agriculture and the world\u2019s population. Crop plants have followed the general pattern of introduction, selection, and hybridization. Once introgressed, selection and breeding strategies have led to new cultivars with improved yield and adaptation. Unfortunately, many of these important traits are typically polygenic. The consequence is that only certain unique allele combinations comply to generate elite performing genotypes. The fixation of a given genotype occurs naturally in species that display an asexual type of seed production named apomixis (i.e. clonal seed production). Unfortunately, apomixis does not naturally occur in major crop species with few exceptions (Citrus, mango and mangosteen). In crop species, apomixis would enable the instantaneous fixation of the complete genome of the best plants. When coupled with male-sterility systems, apomictic reproduction (with no need for male contribution) could help in addressing issues related to transgene escape from GM crops to organic or conventional crops, and thereby allow for better coexistence systems. This trait by itself is highly valuable for agriculture, but despite many efforts it has never been possible to introduce it into the domesticated crop species of today. The financial and economic impacts of the development of apomixis technology and its application to major crops are amazing (\u20ac1800-2300 million per annum per crop). The overall goal of the proposal is to allow for a synergy of inter-related European and international expertise to better understand the mechanisms of sexual/apomictic plant reproduction and to facilitate the application of this increased knowledge in the development of new approaches for agriculture and food industry to increase productivity.", "To": ["2019-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2015-02-01"], "Project_ID": ["645674"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Global searches for dark matter and new physics with GAMBIT using effective field theory"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["DarkGAMBIT"], "Technology_Description": "\"The nature of dark matter (DM) is arguably the biggest mystery in fundamental physics. Many experimental efforts are underway which aim to detect this elusive matter and measure its properties, using a wide variety of techniques, however to make full use of this data a combined statistical analysis must be performed which makes use of the data from all these experiments simultaneously, and compares this data to the predictions of many different theories while including all uncertainties, correlations and theoretical nuances self-consistently. Analyses of this kind are known as \"\"global fits\"\". I propose to use a newly developed, open-source global-fitting tool called GAMBIT to perform the largest and most robust combined statistical analysis of DM data to date. To do this I will extend the capabilities of GAMBIT to allow it to work with a class of models known as \"\"effective theories\"\" which efficiently parameterise the degrees of freedom relevant to experiments at a particular energy scale, so that a global fit can be performed in a fully model-independent way. This will require several connected layers of effective theory to be utilised, to account for the different energy scales involved in the diverse set of DM experiments currently underway. The project is highly interdisciplinary and makes use of recent theoretical developments and experimental results in high energy physics, particle astrophysics, astronomy, nuclear physics, and computational statistics. The proposal will generate a transfer of knowledge to the host institution while developing the candidate's theoretical expertise in new directions, particularly particle astrophysics. The results of the project will be of wide use to the dark matter community, both in terms of direct analysis results and via the development of open-source computational tools for use in future analyses, and will provide robust guidance to experimentalists as to which dark matter candidates are the most promising.\"", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["752162"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE PARIS III SORBONNE NOUVELLE"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Film Heritage and Archival Practices: Past and Present Transcontinental Encounters"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["TRANSARCHIVES"], "Technology_Description": "The main question that guides this research project is: what can Europe learn about its past and present film archiving and heritage practices through collections kept abroad? Focusing on Latin America, the objective of this Fellowship is to identify how the dissemination of European film heritage informs past and present archival practices, and the understanding of both European identity and its representations. It will analyse a decade (1948\u20131959) of circulation of films between both continents shaped by the creation of Cinematheques affiliated with the International Federation of Film Archives (FIAF). It will concentrate, more specifically, on the film exchanges between the Cin\u00e9math\u00e8que Fran\u00e7aise and the Cinematheques of Argentina, Brazil and Uruguay. Nowadays, especially for younger generations, it is difficult to imagine the way films travelled in the 1950s. To gain a better understanding of why these four institutions entered this exchange circuit, it is necessary to analyse the actual corpus, especially now that digital technologies are making these films visible again. Adopting an inter-archival and multilingual methodology, which expands cross-continentally, this Fellowship will emphasise the transnational dimensions of film and to highlight the common connections between archival collections around the world. This innovative approach will demonstrate the value of analysing the history of exhibition abroad to review and complement the European film histories written until now. A thorough study of these channels of European film dissemination will also help to understand past European film archiving and heritage practices in order to assist present institutional and policy-making decisions related to film preservation, exhibition and accessibility more broadly.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["746257"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF GLASGOW"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Stressfully Transmitted Diseases: How your partner\u2019s past stress affects your current and future health"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["STressD"], "Technology_Description": "Early-life stress can reduce the lifespan of individuals and recent work shows that this lifespan reduction can be transmitted to reproductive partners. However, the mechanisms that allow early-life stress to damage the health of individuals that did not experience early-life stress themselves have been little studied. ", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["751356"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CENTRE INTERNACIONAL DE METODES NUMERICS EN ENGINYERIA"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Towards Submarine Landslides and Their Consequences"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["ToSubC"], "Technology_Description": "The last decade has witnessed a boom in offshore infrastructures, including not only oil and gas platforms and submarine pipelines due to the shift of energy exploration from onshore to offshore but also offshore wind farms, offshore electricity grid infrastructure, and submarine communication cables and routes. This boom significantly enhances the importance of the estimation of potential submarine landslides and their consequences. It is true that submarine landslides may have a unexpectedly long travel distance and damage infrastructure thousands of kilometers away. However numerical modelling of the entire process of submarine landslides is a long-standing challenge. In addition to constitutive models for describing both solid-like and fluid-like behaviour of sediments, it requires also advanced numerical approaches capable of tackling extremely large deformation experienced by materials as well as interactions between structures, seawater, and sediments. This project is motivated by these challenges and aims to develop innovative continuum models and numerical approaches for simulating submarine landslides and their consequences. A unified mixed Lagrangian finite element formulation will be derived for handling solid mechanics (infrastructure), fluid dynamics (seawater), and poromechanics (sediments). Viscoeplastoplastic constitutive models will be developed for capturing the solid-fluid transitional behaviour of sediments. The proposed formulation and models will be implemented on a high performance computing based numerical platform within the framework of the particle finite element method for fully coupled analyses of submarine landslides. The intended outcome is a computational tool that can simulate the complete process of real-world submarine landslides, ranging from the initiation of failure through the sliding process to the final deposition and predicting their impact on offshore infrastructures.", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-08-01"], "Project_ID": ["744281"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["Syrian Imaginations of Europe"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["SYRMAGINE"], "Technology_Description": "Refugees\u2019 attempts to flee to a certain country are usually preceded by imaginations about possible destination countries. These imaginations not only contribute to refugees\u2019 decisions where to seek asylum but also have an effect on how refugees experience realities when they eventually arrive in the destination country. The research project \u2018SYRMAGINE \u2013 Syrian Imaginations of Europe\u2019 focusses on how Europe is imagined by Syrian refugees settling in Syria\u2019s neighbouring countries and examines how refugees\u2019 imaginations affect their attitudes to seek asylum in European countries. SYRMAGINE understands \u201cgeographical imaginations\u201d of Europe as subjective human conceptions of a geographical location and stresses the differences between \u201cimagined regions\u201d and reality. The project adopts an interdisciplinary mixed-method approach combining a large sample of individual surveys, semi-directive interviews and an online ethnography in two recipient and transit countries of Syrian refugees in the Middle East, Lebanon and Turkey. ", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["748344"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSIDAD DE GRANADA"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Soft Computing and Computer Vision for Comparative Radiography in Forensic Identification"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["SKELETON-ID"], "Technology_Description": "There is an urgent need of providing forensic practitioners with accurate, robust, unbiased and automate identification systems. This fact makes more sense in the field of forensic anthropology due to the poor technological development, the increasing number of mass disasters, and the unapproachable and shameful number of unidentified people in the EU. SKELETON-ID is intended to fill this technological gap by proposing a novel computer-aided automatic paradigm, which will be implemented and validated through the development of clavicle and frontal sinus identification systems.", "To": ["2020-03-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-04-01"], "Project_ID": ["746592"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich"], "EU_Contribution": ["EUR 175 419,60"], "Project_Title": ["Quantifying atmospheric ice nucleating particle (INP) concentrations via advances in measurement techniques and field studies of ice nucleation"], "Total_Cost": ["EUR 175 419,60"], "Country": ["Switzerland"], "Project_ACR": ["ATM-METFIN"], "Technology_Description": "The focal point of the research proposal is to combine the current technological advancement and scientific questions regarding the unknowns of atmospheric ice nucleation. Ice nucleation is an important pathway for cloud formation and initiation of precipitation, therefore playing a significant role in the Earth\u2019s hydrological cycle and energy and radiative balance. Several questions pertinent to ice nucleation remain unanswered, partially due to gaps in instrumental technology and lack of ambient measurements. The proposed work primarily focuses on the mechanisms of ice nucleation in the atmosphere, more specifically the number, physics and chemistry of biogenic and anthropogenic aerosol particles able to act as ice nucleating particles (INP). Field measurements with technological improvements to the existing Portable Ice Nucleation Chamber (PINC) are planned. One of the goals is to continue the time series measurements of INP parameters at the Iza\u00f1a Observatory in Tenerife, where measurements have been ongoing since 2013 by the host institution. Since the INP concentration exponentially decreases with increasing temperature, and it is the warmer sub-zero temperatures that are more relevant for the initial ice formation in mixed-phase, the goal is to extend the measurements of INP parameters at the Iza\u00f1a Observatory in Tenerife to temperatures above \u221230\u00b0C. Using additional instrumentation in the field, the role of mineral dust, particles of anthropogenic origin and marine primary biogenic particles as potential INP will be investigated in more detail. From a technical perspective, the work will concentrate on lowering the detection limits of PINC and on improving its ability to differentiate between water droplets and ice crystals. These improvements will allow measuring INP at warmer sub-zero temperatures and in immersion/condensation mode, both of which are more relevant for the first ice formation in supercooled clouds than our current measurements.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["751470"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITETET I TROMSOE"], "EU_Contribution": ["EUR 208 400,40"], "Project_Title": ["Chip-based MUSICAL nanoscopy for imaging endocytosis pathways of phage viruses in liver sinusoidal endothelial cells"], "Total_Cost": ["EUR 208 400,40"], "Country": ["Norway"], "Project_ACR": ["MUSICAL"], "Technology_Description": "Research in biology is both empowered and limited by the fluorescence imaging technology, which has witnessed a huge leap in resolution limits through super-resolved optical microscopy or also referred as optical nanoscopy. Over the last few decades, numerous optical nanoscopy techniques have been reported for either spatial or temporal resolution enhancement. Nevertheless, the present state-of-the-art of optical nanoscopy lacks to provide high optical resolution (50 nm or better) at high temporal resolution (~1 Hz) over large field of view (> 500 X 500 \u03bcm2) in live-cell friendly imaging conditions, such as without special buffer/fluorophores and with minimum photo-toxicity. In this proposal, the aim is to provide ~50 nm optical resolution at significantly small temporal scales (~ seconds) in photochemical environment which is physiologically conducive for in-vivo bio-imaging applications. This is achieved by incorporating complementary knowledge and intra-disciplinary skills on the computational nanoscopy (of the experienced researcher, ER) and chip-based optical nanoscopy technique (developed by the hosting PI). The aim is to apply Multiple Signal Classification algorithm (MUSICAL), a computational nanoscopy algorithm developed by the experienced researcher with the fluctuating illumination provided by waveguide chip-based optical nanoscopy developed at the host university, namely Universite it Troms\u00f8, under the ERC funded project (Nanoscopy, PI: Ahuliwalia). The technique shall be used to image and understand endocytosis transport-highway of phages virus in liver endothelial scavenger cells.", "To": ["2019-06-08, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-09"], "Project_ID": ["749666"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSIDAD AUTONOMA DE MADRID"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Exploiting supramolecular interactions in phthalocyanine chemistry"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["PhthaloSupra"], "Technology_Description": "The present project aims at realizing a significant step forward in the use of noncovalent interactions as a \u201ctool\u201d to self-assemble phthalocyanines (Pc), planar and aromatic macrocycles which possess several unique physicochemical properties such as an intense absorption in the red/near-infrared region of the solar spectrum, a rich redox chemistry, and a tuneable bandgap. In PhthaloSupra, the fellow will prepare stable Pc-based supramolecular polymers self-assembled though the combination of pi-stacking, and hydrogen or halogen bonding interactions, noncovalent interactions which have never been used \u201csimultaneously\u201d to self-assemble in a controlled fashion Pc derivatives into supramolecular polymers. For such ensembles, he will study some fundamental properties such as their self-assembly mechanism, light-harvesting capability, and helical chirality, all aspects that are raising nowadays a great deal of scientific attention. The photovoltaic properties of some of the prepared architectures will also be investigated contributing to address the European and international growing interest towards reducing energy consumption through the realization of smart materials for low-cost optoelectronic technologies. Diffusion of the PhthaloSupra achievements will be given not only to specialized researchers, but also, an importantly, to the general public in the form of several outreach activities. Undoubtedly, the opportunity for the candidate to work in a group of the highest scientific quality such as the one of Prof. Torres, and in a highly multidisciplinary and challenging project such as PhthaloSupra will strengthen his potential to mature further to an independent, highly trained researcher. Moreover, he will develop transferable skills, such as research management and organization, competencies which will help him to function more effectively in multidisciplinary and multicultural environments, thus improving his career perspectives.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["752038"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE"], "EU_Contribution": ["EUR 175 419,60"], "Project_Title": ["Game of Drones: Multimedia Streaming with Flying Terminals in Next Generation Mobile Networks"], "Total_Cost": ["EUR 175 419,60"], "Country": ["Switzerland"], "Project_ACR": ["GAMODRONE"], "Technology_Description": "The use of civilian unmanned aerial vehicles (UAV) that allow capturing and streaming video in real-time is steadily increasing. One of the reasons for such interest is that the use of drones, either single units or in swarms, is currently being considered for reconnaissance missions in emergency situations such as earthquakes, radiation leakage in nuclear power plants or in case of a terrorist attack. More challenging applications such as package delivery services are also being considered, in which data speed, reliability and video quality are of paramount importance. Another promising application for civil UAV\u2019s is to help providing flexibility to beyond-5G networks. The main goal of the project (highest priority) is to study efficient adaptive video compression and streaming solutions for interactive and non-interactive omnidirectional video that allow making an efficient use of the available bandwidth while satisfying target delay and video quality requirements. In order to deal with the limited knowledge of the interference environment at the receiver side (which is a likely scenario for airborne terminals) I will study efficient interference management and multi-user detection techniques. In order to further optimize the bandwidth usage, the correlation between the information of different terminals (e.g., when two or more drones within a swarm are capturing partly overlapping panoramas) will be exploited, so that redundant information is kept at the minimum necessary. The secondary goal (lower priority) of the project is the study of how to efficiently exploit the unique UAV\u2019s mobility characteristics to provide additional coverage in congested network areas. This will be carried out by capitalizing on the results of the main goal. In particular, the channel characterization and the interference management techniques studied in the context of video streaming will be adapted to the use of drones as 3D-mobile gap-fillers.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["751062"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSIDAD AUTONOMA DE MADRID"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Post-crisis urban governance transformations in Southern Europe: a comparativist approach"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["URBANiTE"], "Technology_Description": "The post-crisis transformations of the socio-political landscapes in Southern Europe have shaped crucial opportunities for emergent political actors and the civil society to introduce new governance mechanisms. Following a turbulent period of social mobilizations, rapid political and institutional transformations are underway at the city, regional and national levels in countries such as Spain and Greece, and particularly in Madrid and Athens. These provide a crucial theoretical, methodological and analytical challenge for urban studies and a key opportunity for the development of a novel relational comparative approach regarding the modifications of urban governance in Madrid and Athens. The prime research aim of URBANiTE is to investigate the ongoing socio-political developments in the two cities, the relationship between civil society and emergent political actors and the ways these shape institutional changes. The project will produce context-sensitive, innovative outcomes on multi-level territorial governance, of high relevance for science, society and policy, in times of sweeping challenges in Europe and beyond. Moreover, it involves integrated interdisciplinary research with policy implications for the governance of inclusive, innovative and reflective societies, hence fully responds to challenges set out in the Horizon 2020 Societal challenges programme. The Fellowship will provide opportunity for knowledge exchange, as the fellow will bring expertise from the UK and Greece on urban politics, citizenship and grassroots social innovation in austerity contexts. It will also allow the fellow to advance her knowledge in an interdisciplinary research environment and learn from a new regional context, which will contribute to greater understandings of urban governance changes, social innovation and policy implementation in contemporary Europe. Lessons generated will be of wider relevance for EU- level urban governance, with transferable outcomes to other contexts.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["747313"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ECOLE NORMALE SUPERIEURE DE LYON"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["AB Initio Simulations for Super-Earths"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["ABISSE"], "Technology_Description": "Since the discovery of the first exoplanet, a gaseous giant planet, two decades of an extensive planet hunt led to an amazing inventory of close-by planet systems. Among these planets a substantial number are slightly larger than Earth but are still expected to be rocky. No similar object exists in the solar system and little is known about them. One interesting aspect is to determine the habitability of these exotic planets and if life could develop there. It is therefore important to determine what is the structure of the deep interior of these planets and if it can generate a protecting magnetic field.", "To": ["2019-09-03, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-04"], "Project_ID": ["750901"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["JOHANNES GUTENBERG-UNIVERSITAT MAINZ"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["European Travel Writing in Context. The Socio-Political Dimension of Travelogues 1760-1850"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["EUTWIC"], "Technology_Description": "\"Euopean Travel Writing in Context\" investigates the thesis that travel writing is a fundamental medium in the process of the major political and social changes in Europe from the late 18th to the middle of the 19th century. In particular, the processes of the formation of collective national identities and cultures as well as the process of the formation of the middle class with its emphasis on the individual\u2019s identity are implicitly depicted, performed and negotiated in travel writing of the period. ", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["751378"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Targeting epigenetic demethylases: development of covalent inhibitors and PROTACs (Proteolysis Targeting Chimeras)."], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["TEDCIP"], "Technology_Description": "Epigenetics is the study of heritable changes in phenotype that does not involve changes in the underlying DNA sequence. Epigenetic modifications are partly inherited, but unlike the genome itself, are cell specific, plastic, and its mechanisms are affected by different factors and processes such as aging, environmental factors or the use of drugs. The epigenetic changes are the result of epigenetic tags (chemical tags) that can determine gene expression. There are two main types of epigenetic modifications: DNA methylation and histone modifications. Many diseases such as cancer, inflammation, neurological and cardiovascular diseases can be related to aberrant histone modification patterns. Since Histone modifications are mainly carried out by three types of proteins (writers, readers and erasers) there is great therapeutic interest in these proteins, since they may influence disease onset and progression. However, the identification of potent and selective inhibitors is challenging due to structural similarities between individual domains of the \u2018epigenetic\u2019 proteins.", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["744389"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich"], "EU_Contribution": ["EUR 143 750"], "Project_Title": ["Automated detection of damage to buildings"], "Total_Cost": ["EUR 143 750"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["ADDABU"], "Technology_Description": "Hail and storm damages represent the most often occurring cases for building insurance companies. Currently, the damage is estimated by an insurance expert, visiting the damaged building and drafting a report. Researchers at the Computer Vision Lab at ETH Zurich joined forces with business and sales people, spinning out the company Casalva, to strongly reduce such costs via automated image analysis. The idea is that the insurers\u2019 clients upload photos of the damages, which will then be analyzed automatically by a computer. This involves computer vision technologies \u2013 grounded in the ERC project VarCity \u2013 to recognize the damaged building structures and to analyze the corresponding textures as to assess the extent of the damage and the estimated costs for its repair. Cutting costs is not the only consideration, as the fast assessment of damages improves customer satisfaction and prevents the occurrence of additional damages because of a delayed repair (like water leaking before repair). Such follow-on damages are estimated to be 20% of overall costs on average and are therefore far from negligible. Guaranteeing a short term response currently is a major issue, as a single storm may affect thousands of buildings. Processing times tend to stretch out due to the peak in cases following such extreme weather events. Over half of hail storm damage cases concern facade structures. The VarCity project produced methods to automatically parse facades into such structures, and to select the best way to describe their textures. These will be refined to optimally deal with the application area. The remaining technical developments and risk mitigations will be funded through other means (a Swiss project that has already been submitted), while this Proof-of-Concept project will focus on equally important aspects like market analysis, development of a corporate identity and graphical house style for the Casalva spin-off, that has been created but should now get market introduction.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["768610"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI ROMA TRE"], "EU_Contribution": ["EUR 168 277,20"], "Project_Title": ["Polymeric Self-Assembling Units for a Controlled Adsorption and Release at the Nanoscale"], "Total_Cost": ["EUR 168 277,20"], "Country": ["Italy"], "Project_ACR": ["NANODRIVE"], "Technology_Description": "Creating novel building blocks, which allow for an easy and large-scale fabrication of complex materials, is a challenge and a central goal of diverse scientific fields, ranging from Physics to Materials Science. ", "To": ["2019-05-01, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-02"], "Project_ID": ["751255"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["WEIZMANN INSTITUTE OF SCIENCE", "WEIZMANN INSTITUTE OF SCIENCE", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 2 499 944"], "Project_Title": ["Lubricating Cartilage: exploring the relation between lubrication and gene-regulation to alleviate osteoarthritis"], "Total_Cost": ["EUR 2 499 944"], "Country": ["Israel", "Israel", "United Kingdom"], "Project_ACR": ["CartiLube"], "Technology_Description": "Can we exploit insights from the remarkably lubricated surfaces of articular cartilage, to create lubricants that may alleviate osteoarthritis (OA), the most widespread joint disease, affecting millions? These, succinctly, are the challenges of the present proposal. They are driven by our recent finding that lubrication of destabilised joints leads to changes in gene-regulation of the cartilage-embedded chondrocytes to protect against development of the disease. OA alleviation is known to arise through orthopedically suppressing shear-stresses on the cartilage, and a central premise of this project is that, by reducing friction at the articulating cartilage through suitable lubrication, we may achieve the same beneficial effect on the disease. The objectives of this project are to better understand the origins of cartilage boundary lubrication through examination of friction-reduction by its main molecular components, and exploit that understanding to create lubricants that, on intra-articular injection, will lubricate cartilage sufficiently well to achieve alleviation of OA via gene regulation. The project will examine, via both nanotribometric and macroscopic measurements, how the main molecular species implicated in cartilage lubrication, lipids, hyaluronan and lubricin, and their combinations, act together to form optimally lubricating boundary layers on model surfaces as well as on excised cartilage. Based on this, we shall develop suitable materials to lubricate cartilage in joints, using mouse models. Lubricants will further be optimized with respect to their retention in the joint and cartilage targeting, both in model studies and in vivo. The effect of the lubricants in regulating gene expression, in reducing pain and cartilage degradation, and in promoting stem-cell adhesion to the cartilage will be studied in a mouse model in which OA has been induced. Our results will have implications for treatment of a common, debilitating disease.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["743016"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 2 499 513,85"], "Project_Title": ["Evolution of regulatory landscapes at multiple timescales"], "Total_Cost": ["EUR 2 499 513,85"], "Country": ["Spain", "Spain"], "Project_ACR": ["Evoland"], "Technology_Description": "Evolution of animal morphology relies on changes in developmental programs that control body plans and organ shape. Such changes are thought to arise form alteration of the expression of functionally conserved developmental genes and their vast downstream networks. Although this hypothesis has a profound impact on the way we view animal evolution, final proof is still lacking. The hypothesis calls for evolution to take place mainly through modifications of cis-regulatory elements (CREs) controlling gene expression. However, these genomic regions are precisely those that we understand the least and, until recently, basic knowledge on how regulatory information is organized in the 3D genome or how to spatio-temporally assign CREs to their target genes was unknown.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["740041"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 1 979 112"], "Project_Title": ["Climate dimension of natural halogens in the Earth system: Past, present, future"], "Total_Cost": ["EUR 1 979 112"], "Country": ["Spain", "Spain"], "Project_ACR": ["CLIMAHAL"], "Technology_Description": "Naturally-emitted very short-lived halogens (VSLH) have a profound impact on the chemistry and composition of the atmosphere, destroying greenhouse gases and altering aerosol production, which together can change the Earth's radiative balance. Therefore, natural halogens possess leverage to influence climate, although their contribution to climate change is not well established and most climate models have yet to consider their effects. Also, there is increasing evidence that natural halogens i) impact on the air quality of coastal cities, ii) accelerates the atmospheric deposition of mercury (a toxic heavy metal) and iii) that their natural ocean and ice emissions are controlled by biological and photochemical mechanisms that may respond to climate changes. Motivated by the above, this project aims to quantify the so far unrecognized natural halogen-climate feedbacks and the impact of these feedbacks on global atmospheric oxidizing capacity (AOC) and radiative forcing (RF) across pre-industrial, present and future climates. Answering these questions is essential to predict if these climate-mediated feedbacks can reduce or amplify future climate change. To this end we will develop a multidisciplinary research approach using laboratory and field observations and models interactively that will allow us to peel apart the detailed physical processes behind the contribution of natural halogens to global climate change. Furthermore, the work plan also involves examining past-future climate impacts of natural halogens within a holistic Earth System model, where we will develop the multidirectional halogen interactions in the land-ocean-ice-biosphere-atmosphere coupled system. This will provide a breakthrough in our understanding of the importance of these natural processes for the composition and oxidation capacity of the Earth's atmosphere and climate, both in the presence and absence of human influence.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["726349"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITAET LEIPZIG"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Designing and screening two dimensional covalent organic frameworks for effective water splitting"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["2D-COF-WS"], "Technology_Description": "In order to mitigate the energy crisis and serious environmental pollution as well as global warming, the conversion of solar energy into chemical fuels including hydrogen has been extensively developed to flexibly and conveniently utilize this clean energy form. Generally, hydrogen can be produced via photocatalytic water splitting under sunlight irradiation. The efficiency of this solar driven process to synthesize hydrogen depends entirely on the selected semiconducting photocatalysts. ", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["751848"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITEIT ANTWERPEN", "UNIVERSITEIT ANTWERPEN"], "EU_Contribution": ["EUR 149 687,50"], "Project_Title": ["Development of a policy to stop the suffering caused by Nodding Syndrome andOnchocerciasis associated epilepsy"], "Total_Cost": ["EUR 149 687,50"], "Country": ["Belgium", "Belgium"], "Project_ACR": ["NSstop"], "Technology_Description": "Nodding syndrome (NS) is a form of epilepsy characterized by head-nodding, often associated with severe intellectual disability, psychiatric problems and early death. Initially, NS was reported only in onchocerciasis-endemic regions in Tanzania, Uganda and South Sudan. Until recently, the cause of the syndrome was unknown. Therefore, no strategy for prevention and cure was possible. Our ERC project (NSETHIO) discovered that NS is only one of the clinical presentations of onchocerciasis associated epilepsy (OAE) and that this form of epilepsy is probably present in all onchocerciasis endemic regions where onchocerciasis is insufficiently controlled. We estimate that the number of excess cases of epilepsy due to onchocerciasis could be as much as 100,000. Based on NSETHIO findings we will develop an innovative comprehensive OAE policy plan that will prevent children from developing OAE and that will reduce the negative consequences of OAE for the economy and society. This plan includes the following components: strengthening community directed ivermectin (IVM) treatment programs (IVM will stop OAE), establishing an SMS based epilepsy surveillance system by epilepsy trained community-directed IVM distributors, developing a community-based care system using evidence based OAE treatment algorithms and a community-awareness program. We will fine tune the plan during 2 OAE stakeholder workshops, field test it in a high OAE prevalence health zone and calculate its cost. We will create an international OAE alliance including scientists and health care workers, representatives of communities and advocacy groups, WHO, Ministries of Health, non-governmental organizations, the pharmaceutical industry and donors to scale up the implementation of these interventions after the end of the NSstop project. Reducing the burden of disease caused by OAE will have great positive cultural, societal and economic impacts on affected families and villages in many parts of Africa.", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["768815"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG", "RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG"], "EU_Contribution": ["EUR 2 069 000"], "Project_Title": ["Molecular Biology of Nascent Chains: Co-translational folding and assembly of proteins in eukaryotes"], "Total_Cost": ["EUR 2 069 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["TransFold"], "Technology_Description": "Biological activity of cells depends on timely production of natively folded proteins by powerful translation and folding machineries. At a critical regulatory intersection of translation and folding, ribosomes act as integration hubs coordinating chaperone, enzyme and membrane targeting factor activity, and mRNA coding sequence specifies local changes in translation speed, influencing folding. Final assembly of proteins into oligomeric complexes however, has long been considered posttranslational and dependent on random collision of fully synthesized diffusing subunits. In a shift of paradigm our recent evidence now suggests that in bacteria, assembly initiates co-translationally assisted by chaperones, and gene organization into operons drives co-localized translation of complex subunits that impacts efficiency of assembly. Fundamental differences in eukaryotes such as rarity of operons and differing chaperone constellations imply a widely different folding and assembly biology, which remains largely unexplored. Our development of the selective ribosome profiling (SeRP) method now allows ground-breaking identification and definition of dynamic interactions of nascent chains, at near-residue resolution. Using SeRP with supporting biochemistry and microscopy, we will unravel the nascent chain molecular biology underpinning protein folding and assembly in yeast. Specifically, we will establish (1) basic features and prevalence of co-translational protein assembly, (2) how chaperones guide co-translational protein folding to affect assembly, (3) whether translation of subunit-encoding mRNAs is spatially organized, and if so, how this occurs, and (4) to what extent translation speed variations affect assembly. Subunit interaction profiles complemented by mRNA localization will expose the timing and interplay of protein folding and assembly steps linked to protein synthesis, establishing a detailed conceptually new biology of complex assembly in eukaryotes.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["743118"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN", "RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN"], "EU_Contribution": ["EUR 1 973 875"], "Project_Title": ["Search for Higgs bosons decaying to charm quarks"], "Total_Cost": ["EUR 1 973 875"], "Country": ["Germany", "Germany"], "Project_ACR": ["HIGCC"], "Technology_Description": "In the standard model of particle physics (SM), the Higgs boson explains the existence of mass of the elementary particles. However, the model suffers from severe weaknesses: radiative corrections drive the theoretical mass of the Higgs boson to extremely high, unnatural values, while the observed mass is rather low (the famous hierarchy problem). Unknown mechanisms of physics beyond the standard model (BSM) must exist to avoid this unnatural situation. Such BSM mechanisms modify the predicted properties and decay patterns of the Higgs boson. The experimental collaborations at the LHC are measuring these decay patterns as precisely as possible.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["724704"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITEIT UTRECHT", "UNIVERSITEIT UTRECHT", "CITY UNIVERSITY OF LONDON"], "EU_Contribution": ["EUR 2 494 278,75"], "Project_Title": ["Forests and Trees: the Formal Semantics of Collective Categorization"], "Total_Cost": ["EUR 2 494 278,75"], "Country": ["Netherlands", "Netherlands", "United Kingdom"], "Project_ACR": ["ROCKY"], "Technology_Description": "Languages have various ways of referring to collections like families, herds and forests. The grammatical properties of collective expressions critically determine how we understand them. The sentences \u201cthis forest is old\u201d and \u201cthese trees are old\u201d categorize an arboreal collection using a concept (\u201cold\u201d), while conveying different meanings. This semantic difference correlates with the difference in grammatical number between the sentences: singular vs. plural. Such effects of collective categorization in language are crucial for understanding the connections between grammar and the mind, as well as for artificial intelligence. However, currently little is known about the mechanisms underlying our linguistic ability to conceptualize collections. This project aims to develop a novel linguistic theory of this ability, applied to a wide range of empirical phenomena and interdisciplinary challenges in computational semantics and comparative linguistics, benefiting from the recent synergy between linguistics and the psychology of concepts. The idea is that when classifying a collection, speakers rely on two inferential principles with mental concepts: (i) geometric inferences: a forest is considered \u201cfar away\u201d if all of its trees are far; (ii) symmetric inferences: two trees are \u201csimilar\u201d if each of them is similar to the other. The leading hypothesis is that uniform interactions between these inferential principles and the grammar of collective expressions account for collective categorization in language. This hypothesis is explored in three work packages, each of which develops the semantic theory and evaluates it on a different interdisciplinary domain: human interaction with geographic information systems, behavioral linguistic experiments, and comparative linguistics. Together, the three components of the project are expected to lead to a theoretical breakthrough in semantic theory and to enrich its interdisciplinary connections with neighboring disciplines.", "To": ["2022-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["742204"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["THE UNIVERSITY OF HUDDERSFIELD", "THE UNIVERSITY OF HUDDERSFIELD", "BATH SPA UNIVERSITY", "INSTITUT DE RECHERCHE ET DE COORDINATION ACOUSTIQUE MUSIQUE - IRCAM", "UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK"], "EU_Contribution": ["EUR 2 471 416"], "Project_Title": ["Interactive Research in Music as Sound:Transforming Digital Musicology"], "Total_Cost": ["EUR 2 471 416"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom", "France", "Ireland"], "Project_ACR": ["IRiMaS"], "Technology_Description": "In an age when technology is revolutionizing the ways in which music is made and distributed, this project proposes correspondingly to transform approaches to musicology, moving from a primarily fixed, text-based approach to one that incorporates as an integral feature the interactive and aural. It brings skills and expertise from music technology to assist in the development of research strategies and software to enable musicological research to engage more directly with sound. It will pioneer a ground-breaking approach to music research in which dynamic interaction with sound is fundamental and music\u2019s temporal and transient nature are central to research investigations and their dissemination, presenting a significant conceptual challenge to the traditional textual bias of much musical research and leading to new enhanced modes of musicological knowledge. Unlike current Digital Musicology, rather than using software primarily to extract quantized data, IRiMaS facilitates research through dynamic interactive engagement with sound.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Denise Ogden", "Tel.: +44-1484-473192", "Fax: +44-1484-472682", "Higher or Secondary Education Establishments", "Denise Ogden", "Tel.: +44-1484-473192", "Fax: +44-1484-472682", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["741904"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION", "FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION"], "EU_Contribution": ["EUR 2 495 838,75"], "Project_Title": ["Connectivity, plasticity and function of an olfactory memory circuit"], "Total_Cost": ["EUR 2 495 838,75"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["MCircuits"], "Technology_Description": "The brain accumulates knowledge by experience-driven modifications of neuronal connectivity and creates models of the world that enable intelligent behavior. It is thought that these processes are based on autoassociative mechanisms of circuit plasticity. However, direct tests of these fundamental concepts are difficult because they require dense reconstructions of neuronal wiring diagrams. We will dissect structural and functional mechanisms of autoassociative memory in telencephalic area Dp of adult zebrafish, the homologue of olfactory cortex. The small size of the zebrafish brain provides essential advantages for exhaustive measurements of neuronal activity and connectivity patterns. Key predictions of theoretical models will be examined by analyzing effects of odor discrimination learning on the dynamics and stability of odor representations in Dp. The underlying structural circuit modifications will be examined in the same brains by circuit reconstruction using serial block face scanning electron microscopy (SBEM). The dense reconstruction of neuronal ensembles responding to learned and novel odors will allow for advanced analyses of structure-function relationships that have not been possible so far. Odor stimulation in a virtual environment will be combined with optogenetic activation or silencing of neuromodulatory inputs to write and disrupt specific olfactory memories and to analyze the effects on behavior and connectivity. The underlying cellular mechanisms of synaptic plasticity and metaplasticity will be examined by electrophysiology, imaging and optogenetic approaches. Mutants will be used to assess effects of disease-related mutations on circuit structure, function and plasticity. These mechanistic analyses are guided by theoretical models, expected to generate direct insights into elementary computations underlying higher brain functions, and likely to uncover causal links between circuit connectivity, circuit function and behavior.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-10-01"], "Project_ID": ["742576"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSIDAD AUTONOMA DE MADRID", "UNIVERSIDAD AUTONOMA DE MADRID"], "EU_Contribution": ["EUR 149 975"], "Project_Title": ["Complementary Adhesive Coatings based on Molecular Association"], "Total_Cost": ["EUR 149 975"], "Country": ["Spain", "Spain"], "Project_ACR": ["CompAd"], "Technology_Description": "Adhesives constitute a potent and very broad technology, offering innovative solutions to a wide range of industries and providing craftsmen and private consumers with easy-to-use technically-advanced products. For every application in which two elements need to be fastened together, a specific adhesive can in principle be formulated. ", "To": ["2018-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["754795"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["UNIVERSIDAD AUTONOMA DE MADRID", "UNIVERSIDAD AUTONOMA DE MADRID"], "EU_Contribution": ["EUR 1 498 625"], "Project_Title": ["Endolysosomal-mitochondria crosstalk in cell and organism homeostasis"], "Total_Cost": ["EUR 1 498 625"], "Country": ["Spain", "Spain"], "Project_ACR": ["EndoMitTalk"], "Technology_Description": "For many years, mitochondria were viewed as semiautonomous organelles, required only for cellular energetics. This view has been displaced by the concept that mitochondria are fully integrated into the life of the cell and that mitochondrial function and stress response rapidly affect other organelles, and even other tissues. A recent discovery from my lab demonstrated that mitochondrial metabolism regulates lysosomal degradation (Cell Metabolism, 2015), thus opening the way to investigate the mechanism behind communication between these organelles and its consequences for homeostasis. With this proposal, we want to assess how mitochondrial crosstalk with endolysosomal compartment controls cellular homeostasis and how mitochondrial dysfunction in certain tissues may account for systemic effects on the rest of the organism. EndoMitTalk will deliver significant breakthroughs on (1) the molecular mediators of endolysosomal-mitochondria communication, and how deregulation of this crosstalk alters cellular (2), and organism homeostasis (3). Our central goals are: 1a,b. To identify metabolic and physical connections mediating endolysosomal-mitochondria crosstalk; 2a. To decode the consequences of altered interorganelle communication in cellular homeostasis 2b. To study the therapeutic potential of improving lysosomal function in respiration-deficient cells; 3a. To assess how unresolved organelle dysfunction and metabolic stresses exclusively in immune cells affects organism homeostasis and lifespan. 3b. To decipher the molecular mediators by which organelle dysfunction in T cells contributes to age-associated diseases, with special focus in cardiorenal and metabolic syndromes. In sum, EndoMitTalk puts forward an ambitious and multidisciplinary but feasible program with the wide purpose of understanding and improving clinical interventions in mitochondrial diseases and age-related pathologies.", "To": ["2022-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-03-01"], "Project_ID": ["715322"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["UNIVERSIDAD AUTONOMA DE MADRID", "UNIVERSIDAD AUTONOMA DE MADRID"], "EU_Contribution": ["EUR 1 750 625"], "Project_Title": ["A bottom-up topological superconductor based on quantum dot arrays"], "Total_Cost": ["EUR 1 750 625"], "Country": ["Spain", "Spain"], "Project_ACR": ["TOPOQDot"], "Technology_Description": "The realization of a topological superconductor (TS) and of Majorana fermion (MF) quasiparticles promises to open new avenues towards decoherence-robust topological quantum computing. However, further developments in this direction, including the investigation of their topological properties, have been hindered by the lack of a fully conclusive demonstration. In setups based on 1D nanostructures, e.g. semiconductor nanowires and magnetic adatom chains, this is linked to the difficulty to unambiguously assign the main reported signatures, a zero-bias peak in Andreev conductance, to MF modes. This proposal aims to overcome these limitations by exploring an alternative approach in which a 1D TS is built from the bottom up. In particular, arrays of proximity-coupled semiconductor quantum dots (QDs) will be explored as a platform for emulating the Kitaev chain. Such an approach offers the advantage that the evolution of subgap states into MF modes is followed during the assembly of the TS, thereby providing conclusive evidence of their realization. It also enables to controllably adjust the chain parameters to their optimal values where the topological array is most robust. ", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["716559"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSITE DE NANTES", "BATH SPA UNIVERSITY", "THE UNIVERSITY OF BIRMINGHAM", "Faculdade de letras da Universidade de Lisboa", "UNIVERSITAET HAMBURG"], "EU_Contribution": ["EUR 1 107 000"], "Project_Title": ["Slavery in Africa: a dialogue between Europe and Africa"], "Total_Cost": ["EUR 1 107 000"], "Country": ["France", "France", "France", "United Kingdom", "United Kingdom", "Portugal", "Germany"], "Project_ACR": ["SLAFNET"], "Technology_Description": "The overall objective of the project is to establish a top-level scientific network of several institutions and research groups from Europe and Africa on the field of slavery studies. It aims at focusing mutual efforts of 13 partners with extended and complementary competences in their respective research fields and at gathering multidisciplinary expertise in slavery-related issues by encouraging the exchange of young and senior researchers from both continents.", "To": ["2020-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["734596"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["UNIVERSIDAD AUTONOMA DE MADRID", "UNIVERSIDAD AUTONOMA DE MADRID"], "EU_Contribution": ["EUR 1 499 500"], "Project_Title": ["Modification of Molecular structure Under Strong Coupling to confined Light modES"], "Total_Cost": ["EUR 1 499 500"], "Country": ["Spain", "Spain"], "Project_ACR": ["MMUSCLES"], "Technology_Description": "Understanding and controlling the properties of matter is one of the overarching goals of modern science. A powerful way to achieve is this by using light, usually in the form of intense laser beams. However, modern advances in nanophotonics allow us to confine light modes so strongly that their effect on matter is felt even when no external fields are present. In this regime of \u201cstrong coupling\u201d or \u201cvacuum Rabi splitting\u201d, the fundamental excitations of the coupled system are hybrid light-matter states which combine the properties of both constituents, so-called polaritons. Little attention has been paid to the fact that strong coupling can also affect internal structure, such as nuclear motion in molecules. First experimental indications for this effect have been found, but current theory cannot explain or predict such changes. We will thus develop theoretical methods that can treat the modification of molecular structure under strong coupling to confined light modes. This will require advances in the microscopic description of the molecules under strong coupling by explicitly including their rovibrational degrees of freedom, as well as techniques to incorporate the influence of these modes in the macroscopic setting of collective strong coupling. In order to achieve this, we will adapt well-known techniques from quantum chemistry and combine them with the concepts of polariton physics. We will investigate what level of control can be gained through this approach, and whether confined light modes could act as a \u201cphotonic catalyst\u201d to control molecular dynamics without requiring an active ingredient. This could present a novel tool to control photochemical reactions that are of paramount importance in the biological mechanisms of vision and photosynthesis, and hold great interest for use in memories, photoswitching devices, light-driven actuators, or solar energy storage. Consequently, this work could have wide-ranging impact on many different fields of science.", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["714870"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["LOUGHBOROUGH UNIVERSITY", "UNIVERSITAT DE BARCELONA", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSITE D'AIX MARSEILLE", "UNIVERSIDAD POLITECNICA DE MADRID", "UNIVERSIDAD AUTONOMA DE MADRID", "UNIVERSITAET STUTTGART"], "EU_Contribution": ["EUR 526 500"], "Project_Title": ["Stability and Transitions in Physical Processes"], "Total_Cost": ["EUR 711 000"], "Country": ["United Kingdom", "Spain", "France", "France", "Spain", "Spain", "Germany"], "Project_ACR": ["TraX"], "Technology_Description": "Many dynamical processes in natural sciences are organized by invariant objects that behave in rather simple ways under time evolution, such as equilibria, periodic orbits, or higher-dimensional invariant surfaces. These objects and the invariant manifolds attached to them act as landmarks that organize the behavior of other trajectories and yield a qualitative description of the dynamics. By computing strategically chosen landmarks, one can obtain considerable information of the possible behaviors of the system.", "To": ["2021-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-03-01"], "Project_ID": ["734557"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["UNIVERSITY OF DURHAM", "UNIVERSIDAD AUTONOMA DE MADRID", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "UNIVERSITEIT LEIDEN", "THE UNIVERSITY OF NOTTINGHAM", "FUNDACION CENTRO DE ESTUDIOS DE FISICA DEL COSMOS DE ARAGON", "RIJKSUNIVERSITEIT GRONINGEN", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "HITS GGMBH", "ISTITUTO NAZIONALE DI ASTROFISICA"], "EU_Contribution": ["EUR 1 350 000"], "Project_Title": ["Latin American Chinese European Galaxy Formation Network"], "Total_Cost": ["EUR 1 561 500"], "Country": ["United Kingdom", "Spain", "Germany", "Netherlands", "United Kingdom", "Spain", "Netherlands", "Spain", "Germany", "Italy"], "Project_ACR": ["LACEGAL"], "Technology_Description": "Spectacular breakthroughs in astronomy have been driven by a combination of observational advances and groundbreaking computer simulations. Simulations are now accepted as being essential for the interpretation and exploitation of data. Europe is a world leader in this area. Our aim is to build on the highly successful FP7 LACEGAL IRSES to avoid fragmentation of expertise and concentration of supercomputer resources in a few groups. The expansion of LACEGAL will build new research collaborations between Europe and the main centres in Latin America and China, and enhance those established under IRSES. The bulk of exchanges will be undertaken by Early Stage Researchers, who will gain access to unique training in high performance computing, equipping them with skills which are much sought after in academia and industry. We also plan network-wide workshops to share knowledge and provide specialized training, disseminating project results and expertise beyond the membership of LACEGAL. Our research program addresses key questions in galaxy formation and the large-scale structure of the Universe. An important goal is to produce the multi-wavelength theoretical models which are urgently needed to meet the challenge posed by upcoming observations. LACEGAL is particularly timely as it will allow us to analyse new data and to prepare for major international projects in which LACEGAL scientists have leadership: 1) The Dark Energy Survey, 2) the European Space Agency's Gaia mission, 3) The Atacama Large Millimetre Array. 4) The Dark Energy Spectroscopic Instrument survey, 5) The PAU Camera Survey, 6) The Javalambra Survey, 7) ESA\u2019s Euclid mission, 8) The Large Synoptic Survey Telescope, 9) The Square Kilometre Array. LACEGAL will help Europe to play a leading role in the breakthroughs expected from these major international projects.", "To": ["2021-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations"], "From": ["2017-03-01"], "Project_ID": ["734374"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["DESCUBRE - FUNDACION ANDALUZA PARA LA DIVULGACION DE LA INNOVACION Y EL CONOCIMIENTO", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "UNIVERSIDAD DE ALMERIA", "UNIVERSIDAD DE CADIZ", "UNIVERSIDAD DE CORDOBA", "UNIVERSIDAD DE GRANADA", "UNIVERSIDAD DE HUELVA", "UNIVERSIDAD DE JAEN", "UNIVERSIDAD DE MALAGA", "UNIVERSIDAD DE SEVILLA", "UNIVERSIDAD PABLO DE OLAVIDE", "Fundacion Publica Andaluza Progreso y Salud", "INSTITUTO MUNICIPAL DE GESTION MEDIOAMBIENTAL - JARDIN BOTANICO DE CORDOBA"], "EU_Contribution": ["EUR 174 782,82"], "Project_Title": ["Open Researchers"], "Total_Cost": ["EUR 368 010,16"], "Country": ["Spain", "Spain", "Spain", "Spain", "Spain", "Spain", "Spain", "Spain", "Spain", "Spain", "Spain", "Spain", "Spain"], "Project_ACR": ["OPENRESEARCHERS"], "Technology_Description": "\u2018Open Researchers\u2019 is the fifth experience of Andalusia in the European Researchers\u2019 Night. The project is designed to increase the awareness of research as a solution to the numerous challenges faced by citizens all around the world and mainly in Europe. The idea of the project, \u2018The future is today: understandable ground-breaking science for a better living\u2019, has been conceived in a time of change, a moment where becomes clearer that we must join efforts to find sustainable, equal, innovative and creative solutions to give answer to the societal challenges. To this end, according to the RRI, it is essential to promote young people\u2019s interest in Science and Research by opening it to general public through its main protagonists, researchers.", "To": ["2017-11-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-NIGHT-2016 - European Researchers' Night"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Spain"], "Activity": ["Other", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2016-04-01"], "Project_ID": ["722930"], "Call_for_Proposal": ["H2020-MSCA-NIGHT-2016"]}, -{"Partners": ["HELMHOLTZ-ZENTRUM FUER UMWELTFORSCHUNG GMBH - UFZ", "UMWELTBUNDESAMT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (UBA GMBH)", "HELSINGIN YLIOPISTO", "FORSCHUNGSZENTRUM JULICH GMBH", "NATURAL ENVIRONMENT RESEARCH COUNCIL", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "SUOMEN YMPARISTOKESKUS", "SENCKENBERG GESELLSCHAFT FUR NATURFORSCHUNG", "MAGYAR TUDOMANYOS AKADEMIA OKOLOGIAI KUTATOKOZPONT", "CONSIGLIO NAZIONALE DELLE RICERCHE", "FUNDACAO DA FACULDADE DE CIENCIAS DA UNIVERSIDADE DE LISBOA FP", "UNIVERSIDAD DE GRANADA", "EIGEN VERMOGEN VAN HET INSTITUUT VOOR NATUUR- EN BOSONDERZOEK", "INSTITUT PO BIORAZNOOBRAZIE I EKOSISTEMNI IZSLEDVANIYA BALGARSKA AKADEMIYA NA NAUKITE", "USTAV VYZKUMU GLOBALNI ZMENY AV CR VVI", "KOBENHAVNS UNIVERSITET", "THE RESEARCH COMMITTEE OF THE TECHNICAL UNIVERSITY OF CRETE", "BEN-GURION UNIVERSITY OF THE NEGEV", "LATVIJAS UNIVERSITATE", "SOVON VOGELONDERZOEK NEDERLAND", "STIFTELSEN NORSK INSTITUTT FOR NATURFORSKNING NINA", "EUROPEJSKIE REGIONALNE CENTRUM EKOHYDROLOGII POLSKIEJ AKADEMII NAUK", "UNIVERSITATEA DIN BUCURESTI", "BIOSENSE INSTITUTE - RESEARCH AND DEVELOPMENT INSTITUTE FOR INFORMATION TECHNOLOGIES IN BIOSYSTEMS", "INSTITUTE OF LANDSCAPE ECOLOGY OF THE SLOVAK ACADEMY OF SCIENCES", "ZNANSTVENORAZISKOVALNI CENTER SLOVENSKE AKADEMIJE ZNANOSTI IN UMETNOSTI", "SVERIGES LANTBRUKSUNIVERSITET", "EIDGENOESSISCHE FORSCHUNGSANSTALT WSL"], "EU_Contribution": ["EUR 899 820"], "Project_Title": ["Advancing the European Long-Term Ecosystem, critical zone and socio-ecological Research Infrastructure towards ESFRI"], "Total_Cost": ["EUR 899 820,01"], "Country": ["Germany", "Austria", "Finland", "Germany", "United Kingdom", "France", "Finland", "Germany", "Hungary", "Italy", "Portugal", "Spain", "Belgium", "Bulgaria", "Czech Republic", "Denmark", "Greece", "Israel", "Latvia", "Netherlands", "Norway", "Poland", "Romania", "Serbia", "Slovakia", "Slovenia", "Sweden", "Switzerland"], "Project_ACR": ["Advance_eLTER"], "Technology_Description": "Advance_eLTER marks a crucial step in building the distributed European Research Infrastructure of Long-Term Ecosystem Research sites and socio-ecological research platforms (eLTER RI) to provide highest quality data and services complementary to the European and global environmental RIs. The project will conduct important conceptual work and preparatory steps towards enabling European-scale investigation of the \u201cCritical Zone\u201d, major ecosystems and socio-ecological systems, targeted at supporting knowledge-based decision making at various levels concerning ecosystem services and biodiversity.", "To": ["2017-12-31, closed project"], "Meta": [""], "Topic_s": ["INFRADEV-02-2016 - Preparatory Phase and support to early phase of ESFRI projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Other", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2017-01-01"], "Project_ID": ["739558"], "Call_for_Proposal": ["H2020-INFRADEV-2016-2"]}, -{"Partners": ["UNIVERSITAT POLITECNICA DE CATALUNYA", "UNIVERSIDAD DE ALCALA", "UNIVERSIDAD DE SEVILLA", "UNIVERSIDAD DE ZARAGOZA", "TECHNISCHE UNIVERSITAET GRAZ", "UNIVERSITE LIBRE DE BRUXELLES", "UNIVERSITA DEGLI STUDI ROMA TRE", "USTAV INFORMATIKY AV CR", "CENTRO DE INVESTIGACION Y DE ESTUDIOS AVANZADOS DEL INSTITUTO POLITECNICO NACIONAL", "UNIVERSIDAD NACIONAL AUTONOMA DE MEXICO", "CENTRO DE INVESTIGACION EN MATEMATICAS AC", "UNIVERSIDAD AUTONOMA DE SAN LUIS POTOSI", "CARLETON UNIVERSITY", "UNIVERSIDAD DE SANTIAGO DE CHILE"], "EU_Contribution": ["EUR 324 000"], "Project_Title": ["Combinatorics of Networks and Computation"], "Total_Cost": ["EUR 382 500"], "Country": ["Spain", "Spain", "Spain", "Spain", "Austria", "Belgium", "Italy", "Czech Republic", "Mexico", "Mexico", "Mexico", "Mexico", "Canada", "Chile"], "Project_ACR": ["CONNECT"], "Technology_Description": "\"Networks are present in our lives in numerous different environments: to name just a few, networks can model social relationships, they can model the Internet and links between web pages, they might model the spread of a virus infection between people, and they might represent computer processors/sensors that have to exchange information.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["734922"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "TTY-SAATIO", "ECOLE SUPERIEURE DE PHYSIQUE ET DECHIMIE INDUSTRIELLES DE LA VILLE DEPARIS", "UNIVERSITEIT TWENTE", "AIRBUS DEFENCE AND SPACE GMBH", "DTNW OFFENTLICHE PRUFSTELLE GMBH", "MILLIDYNE OY", "UNIVERSITAT ZURICH"], "EU_Contribution": ["EUR 3 901 820,76"], "Project_Title": ["Lubricant impregnated slippery surfaces"], "Total_Cost": ["EUR 3 901 820,76"], "Country": ["Germany", "United Kingdom", "Finland", "France", "Netherlands", "Germany", "Germany", "Finland", "Switzerland"], "Project_ACR": ["LubISS"], "Technology_Description": "LubISS, Lubricant Impregnated Slippery Surfaces, is the first European Training Network with the main objectives of designing, characterizing, and modelling low adhesive easy-to-clean surfaces for anti-icing and anti-fouling. In a coordinated effort among 9 world-class academic institutions and industrial partners from 6 European countries (Finland, France, Germany, Great Britain, Netherlands, Switzerland), advanced lubricant impregnated surfaces will be developed. Drawing upon the distinguished expertise within the consortium, textured surfaces impregnated with a lubricating liquid or gel will be designed and fabricated through modern experimental preparation, multi-scale characterization methods, and high power simulation tools. With these broad capabilities, the LubISS network offers a unique training platform for Early Stage Researchers (ESRs) in a multidisciplinary research endeavor of great technological, industrial and environmental importance. The recently introduced concept of lubricant impregnated surfaces is a promising approach to reduce the adhesion of ice as well as biofilm-forming bacteria-to-surfaces. To achieve societal impact, understanding the intimate relationships between the impregnating lubricant, the surface topography, and the adhesion of ice, bacteria, or other biofouling microorganisms is critical. The general aim of this ITN is two-fold: 1) to establish a fundamental understanding between these relationships through academic and industrial collaborations in physics, chemistry, biomedicine, materials science and engineering, and 2) to educate and train young researchers in this vital area of technology. The LubISS network will investigate many aspects of lubricant impregnated surfaces, including the optimization of the lubricant stability under static and dynamic flow conditions, methods for replenishing the lubricant for long-term applications, and benchmarking against state-of-the-art surfaces.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["722497"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Single Crystalline Halide Metal Perovskites Based Optoelectronics"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["PEROPTO"], "Technology_Description": "The emerging methylammonium lead halide perovskites are near-ideal semiconducting materials. They can be easily formed in to thin semiconducting films, suitable for use in a wide range of optoelectronic devices including solar cells and light emitting diodes, giving them huge potential to replace existing semiconductors in these roles. However, the films normally used in those devices are polycrystalline, containing a high density of grain boundaries and defects which intrinsically limits the performance of these otherwise exceptional materials. The ultimate goal of this fellowship is to integrate ultrathin large scale perovskite single crystal into optoelectronic devices for the first time, leading to a step change in device performance, comparable to that realized when single-crystal silicon was first achieved. This development will be underpinned by a detailed experimental investigation to determine the impact of single-crystal preparation on the electronic and spectroscopic properties of perovskite film, particularly exploring charge carrier diffusion in a material with low defect density and minimal grain-boundaries. Ultimately, we will establish whether a cheap, printable material can achieve optoelectronic devices at the thermodynamic limit \u2013 a goal of the community for the last quarter century. This project will tackle first the synthetic challenges of producing single crystalline perovskite materials with controllable dimensions, and subsequently their integration into optoelectronic devices. This proposal takes advantage of the unique opportunity afforded by the skills of the applicant in the synthesis of controlled dimensional single crystalline perovskite materials and the fabrication of optoelectronic devices, with the world-class materials and spectroscopic characterization expertise at the Cavendish Laboratory. The success of this proposal will place Europe at the forefront of research in the disruptive and dynamic field of perovskite optoelectronics.", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["750677"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAT ZURICH", "UNIVERSITAT ZURICH"], "EU_Contribution": ["EUR 2 500 000"], "Project_Title": ["GeoViSense: Towards a transdisciplinary human sensor science of human visuo-spatial decision making with geographic information displays"], "Total_Cost": ["EUR 2 500 000"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["GeoViSense"], "Technology_Description": "Well-designed mobile, human responsive geographic information technology could improve the lives of millions who daily need to make time critical and societally relevant decisions on the go. However, what are the basic processes with which humans make visuo-spatial decisions when guided by responsive geographic information displays? Visualization research todate has been driven by technical and computational advances to overcome data deluges, but we still have a poor understanding whether, how, and when visual displays support spatio-temporal decision making and action, and for which kinds of users. We will break new ground to overcome this transdisciplinary knowledge gap and aim to: (1) integrate fragmented human-visualization-environment research across the sciences including natural, social/behavioral, and the engineering sciences, all critical to tackle this interdisciplinary problem, (2) develop missing, empirically evaluated design guidelines for human-computer interfaces of current/emerging mobile geographic information technology to support affective, effective, and efficient spatio-temporal decision-making, (3) develop unconventional evaluation methods by critical examination of how perceptual, cognitive, psycho-physiological, and display design factors might influence visuo-spatio-temporal decision making across broad ranges of users and mobile use contexts, and (4) scale up empirical methods from to-date controlled behavioral lab paradigms towards a new in-situ mobile human sensor science. A paradigm shift from current lab-based neuro-cognitive and affective science towards a location-based, close human sensing science will radically change the way we study human behavior across science. In doing so, we can improve spatio-temporal every-day decision making with graphic displays, and facilitate sustainable solutions for the increasingly mobile digital information society having to mitigate environmental emergencies, human refugee crises, or terror attacks.", "To": ["2022-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["740426"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["LUNDS UNIVERSITET", "LUNDS UNIVERSITET"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Neural circuits underlying complex brain function across animals - from conserved core concepts to specializations defining a species\u2019 identity"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["BrainInBrain"], "Technology_Description": "The core function of all brains is to compute the current state of the world, compare it to the desired state of the world and select motor programs that drive behavior minimizing any mismatch. The circuits underlying these functions are the key to understand brains in general, but so far they are completely unknown. Three problems have hindered progress: 1) The animal\u2019s desired state of the world is rarely known. 2) Most studies in simple models have focused on sensory driven, reflex-like processes, and not considered self-initiated behavior. 3) The circuits underlying complex behaviors in vertebrates are widely distributed, containing millions of neurons. With this proposal I aim at overcoming these problems using insects, whose tiny brains solve the same basic problems as our brains but with 100,000 times fewer cells. Moreover, the central complex, a single conserved brain region consisting of only a few thousand neurons, is crucial for sensory integration, motor control and state-dependent modulation, essentially being a \u2018brain in the brain\u2019. To simplify the problem further I will focus on navigation behavior. Here, the desired and actual states of the world are equal to the desired and current headings of the animal, with mismatches resulting in compensatory steering. I have previously shown how the central complex encodes the animal\u2019s current heading. Now I will use behavioral training to generate animals with highly defined desired headings, and correlate neural activity with the animal\u2019s \u2018intentions\u2019 and actions - at the level of identified neurons. To establish the involved conserved core circuitry valid across insects I will compare species with distinct lifestyles. Secondly, I will reveal how these circuits have evolved to account for each species\u2019 unique ecology. The proposed work will provide a coherent framework to study key concepts of fundamental brain functions in unprecedented detail - using a single, conserved, but flexible neural circuit.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["714599"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["LUNDS UNIVERSITET", "LUNDS UNIVERSITET"], "EU_Contribution": ["EUR 1 499 905"], "Project_Title": ["High Resolution Mapping of Fetal and Adult B Cell Fates During Ontogeny"], "Total_Cost": ["EUR 1 499 905"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["FatemapB"], "Technology_Description": "FateMapB aims to understand how the unique differentiation potential of fetal hematopoietic stem and progenitor cells (HSPCs) contribute to functionally distinct cell types of the adult immune system. While most immune cells are replenished by HSPCs through life, others emerge during a limited window in fetal life and sustain through self-renewal in situ. The lineage identity of fetal HSPCs, and the extent of their contribution to the adult immune repertoire remain surprisingly unclear. I previously identified the fetal specific RNA binding protein Lin28b as a post-transcriptional molecular switch capable of inducing fetal-like hematopoiesis in adult bone marrow HSPCs (Yuan et al. Science, 2012). This discovery has afforded me with unique perspectives on the formation of the mammalian immune system. The concept that the mature immune system is a mosaic of fetal and adult derived cell types is addressed herein with an emphasis on the B cell lineage.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["715313"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 2 348 483"], "Project_Title": ["Specialized Ribosomes for Neuronal Protein Synthesis"], "Total_Cost": ["EUR 2 348 483"], "Country": ["Germany", "Germany"], "Project_ACR": ["NeuroRibo"], "Technology_Description": "The ability of the nervous system to respond adaptively relies on modifications to existing proteins as well as changes in gene transcription and mRNA translation. It is now clear that synapses possess the capacity for local protein synthesis, owing to the localization of ribosomes and mRNAs within dendrites. There is emerging interest in the possibility that ribosomes, as cellular machines, are not as static as typically assumed- and may be heterogeneous in composition and specialized for particular functions and cellular compartments. Intriguingly, several studies have noted the presence of ribosomal protein mRNAs in the dendrites and axons, raising the possibility that locally synthesized ribosomal proteins might serve to modify the local ribosome population. Amongst the players in protein synthesis, many signaling proteins, RNA-binding proteins, and most translation factors have been considered as potential regulatory hubs. The ribosomes, thus far, have not been considered. Here we propose to discover the nature and diversity of ribosomes present in neurons, their dendrites and their synapses in the rodent brain. Using a combination of RNA-sequencing, Mass Spectrometry, Fluorescence In situ Hybridization, and new labelling approaches to visualize nascent proteins, we will determine whether neuronal ribosomes are heterogeneous and specialized in different subcellular compartments. The proposed experiments will determine the relationship between the ribosome composition and the neuronal mRNAs that undergo translation. We will also examine how plasticity sculpts the ribosome population to regulate the changes in the proteome that are dynamically regulated by ongoing synaptic events and plasticity.", "To": ["2022-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-08-01"], "Project_ID": ["743216"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["THE UNIVERSITY OF WARWICK"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Tuning mechanical properties of elastomers with stereocontrolled \u03c0-bonds using Wittig chemistry"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["POLY-WITTIG"], "Technology_Description": "Elastomer materials (or rubbers) are hugely important and widely used as a result of their ability to be deformed yet return to their original size and shape upon removal of stress. Owing to these properties and their wide-ranging applicability, a significant body of research has been, and continues to be directed towards the discovery of new materials with specific properties for a wide array of application areas. The properties of elastomers are dependent on a number of factors such as chain length, topology, tacticity, pendant functionality, or cross-linking density. Specifically, the mechanical characteristics of natural elastomers, e.g., those based on polyisoprene, are known to be highly dependent upon the stereochemistry of the double bond in the isoprene unit. However, this concept is seldom exploited to modulate properties of synthetic elastomers despite the potential clear advantages to create materials in which the control over their mechanical properties can be decoupled from their functionality. This is primarily a consequence of the inherent challenges associated with metal-catalyzed stereocontrolled polymerisations. The POLY-WITTIG project proposes to utilize the highly practical Wittig reaction to modulate the stereochemistry of the \u03c0-bond in the elastomer backbone to inturn allow the modulation of materials properties to be controlled. Additionally, heteroatom-modified Wittig variants will be used to synthesize and analyze mechanical properties of elastomers with heteroatom\u2013carbon \u03c0-bonds (e.g., N=C or P=C). Thus, the versatility of Wittig chemistry will provide the unprecedented opportunity to systematically study a library of isolobally substituted elastomers.", "To": ["2019-06-25, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-26"], "Project_ID": ["751150"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Unravelling neuronal heterogeneity in energy homeostasis regulation"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["ARC-NeuroHet"], "Technology_Description": "This MSCA Reintegration proposal is aimed to study the heterogeneity of neuronal populations implicated in the maintenance of energy balance. Because of their location, neurons in the arcuate nucleus of the hypothalamus (ARC) integrate nutrient and hormonal signals carried in the blood. Then, they regulate downstream neuron\u2019s activity in order to adapt food intake and energy expenditure. Deregulation of energy homeostasis can lead to obesity and diabetes, two of the major chronic diseases in the EU. AgRP neurons, an ARC population, have a prominent role in the regulation of food intake and systemic insulin sensitivity. They establish axonal projections with several brain areas and recent evidences show that each sub-circuit can have a specific function in the regulation of food intake and/or glucose homeostasis. For this fellowship I propose to use an innovative experimental approach to investigate a specific novel AgRP neuronal subpopulation, characterized by the expression of the UDP-receptor, P2Y6, as a first step to unravel the heterogeneity of the total population. Although P2Y6 activation increases short-term food intake, its effects on glucose homeostasis are still unknown. I plan to combine new recombinase technologies with state of the art techniques to genetically identify the AgRP, P2Y6 subpopulation and then: 1) characterize their in vivo dynamic response to physiological activators; 2) map specific AgRP+, P2Y6+ sub-circuits and dissect their role in each facet of energy homeostasis; and 3) investigate new molecular markers, as possible drugable targets. Results from this project will unveil new aspects of neuronal heterogeneity that participate in the regulation of energy homeostasis and will contribute to design new strategies to curb the actual obesity trends. The completion of this MSCA fellowship represents an exceptional opportunity to reinforce my professional maturity and to develop my independent research line.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-04-01"], "Project_ID": ["752319"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KAROLINSKA INSTITUTET"], "EU_Contribution": ["EUR 185 857,20"], "Project_Title": ["Pericyte-derived tumor stroma \u2013 a target for cancer therapy"], "Total_Cost": ["EUR 185 857,20"], "Country": ["Sweden"], "Project_ACR": ["PERICYTEStroma"], "Technology_Description": "Cancer is a devastating diagnosis since treatments to prevent a lethal outcome are limited. Tumor constitutes a complex tissue consisting of malignant cells and stromal cells. Emerging studies have shown the importance of stroma in tumor growth, invasion, and metastasis highlighting its potential as an attractive target for cancer therapy. However, the source of tumor stroma generating cells remains elusive. Generation of connective tissue is a general feature of scarring and fibrosis. While scarring is part of the wound healing response, fibrosis represents a failure to terminate tissue repair. In this context, tumors can be considered as \u201cwounds that do not heal\u201d. While studying spinal cord injury-induced scarring, a subpopulation of perivascular cells, type A pericytes, has been shown to be a major source of the stromal scar. Type A pericytes are embedded in the vascular wall but proliferate and leave blood vessels upon injury, differentiating into fibroblast-like cells that deposit extracellular matrix and form the stromal scar. Here, I propose to determine whether type A pericytes are a source of tumor stroma and whether blocking type A pericyte-derived stroma formation can impede cancer progression. Single cell studies to determine pericyte heterogeneity within malignant and non-malignant tissue will be performed. This characterization of heterogeneity is important to distinguish stroma-forming pericytes from the non-forming ones and from tumor cell-derived pericytes as described in Glioblastoma multiforme (GBM). Furthermore, by using combinations of pericyte reporter mice with genetic tools to manipulate pathways regulating cell proliferation and recruitment within specific pericyte subpopulations, I aim to investigate underlying mechanisms mediating pericyte-derived stroma generation. Studying stroma formation using the GBM mouse model, the proposed research intends to uncover common mechanisms of tumor stroma formation and identify new targets for therapy.", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["707449"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["LUNDS UNIVERSITET", "LUNDS UNIVERSITET"], "EU_Contribution": ["EUR 1 498 732"], "Project_Title": ["Optimal diversity in immunity \u2013 to overcome pathogens and maximize fitness; moving from correlative associations to a more mechanistic understanding using wild songbirds."], "Total_Cost": ["EUR 1 498 732"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["Optimal-Immunity"], "Technology_Description": "The Major Histocompatibility Complex (MHC) genes are intensively studied genes in association with disease resistance. MHC proteins are essential for initiating every adaptive immune response and MHC is probably the most extreme example of how selection from a wide range of pathogens maintains high diversity in host immunity genes. However, the functions of the MHC proteins are only known in humans and model organisms, species that cannot be studied under natural conditions. There is therefore a need to study function of MHC proteins in species that can be thoroughly monitored in their natural habitat under varying pathogen regimes and over several generations. These parameters can be assessed in wild songbirds making them excellent study systems. Songbirds have large numbers of MHC gene copies, although little is known about how these affect their immune responses. Does high MHC copy number indicate that songbirds can recognize and combat more pathogens than other animals? They do fight infections satisfactory at their breeding, stopover and overwintering sites. ", "To": ["2021-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-04-01"], "Project_ID": ["679799"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["LUNDS UNIVERSITET", "LUNDS UNIVERSITET"], "EU_Contribution": ["EUR 1 496 625"], "Project_Title": ["Integrative omics of heart failure to inform discovery of novel drug targets and clinical biomarkers"], "Total_Cost": ["EUR 1 496 625"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["inHForm"], "Technology_Description": "Heart failure is a leading cause of morbidity and mortality in the aging European populations. It is the end-stage of myocardial and valvular disease, arising from loss of viable or functional muscle cells in the heart. Therapy is complicated by the multitude of causes and comorbidities of heart failure. New therapeutic targets and clinical biomarkers to individually tailor therapy (\u2018precision medicine\u2019) are greatly needed. This research program aims to realize the promise of precision medicine by applying an integrated proteomic, genomic and epidemiological approach to the underlying causes, mechanisms and consequences for heart failure. The program builds on unique Swedish nation-wide disease registers and large biobanks, the translational research profile of the investigator and experience in genomics, epidemiology and proteomics. The program includes five work packages: (1) comprehensive plasma protein profiling through a discovery pipeline including novel microarray-based methods and mass spectrometry in a population-based cohort of 6000 subjects and clinical cases to identify subjects at risk for heart disease; (2) assessment of heritable components to outcomes in heart disease using nation-wide Swedish registers; (3) genome-wide discovery of variants associated with risk of and outcomes in heart disease as well as endophenotypes for cardiac structure and function, using resequencing and DNA microarrays in large population-based cohorts including >70,000 subjects from three generations; (4) expression profiling in human heart samples and a novel human cardiomyocyte strain assay to translate genomic and proteomic findings to understanding of pathophysiological mechanisms; (5) evaluate the clinical importance of plasma proteins and genetic variants in >3000 clinical cases. This research program is anticipated to result in new insights into the pathophysiology of heart failure and discovery of drug targets and clinical biomarkers.", "To": ["2021-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-04-01"], "Project_ID": ["679242"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["LUNDS UNIVERSITET", "LUNDS UNIVERSITET"], "EU_Contribution": ["EUR 1 492 011"], "Project_Title": ["Sex-limited experimental evolution of natural and novel sex chromosomes: the role of sex in shaping complex traits"], "Total_Cost": ["EUR 1 492 011"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["ComplexSex"], "Technology_Description": "The origin and evolution of sexual reproduction and sex differences represents one of the major unsolved problems in evolutionary biology, and although much progress had been made both via theory and empirical research, recent data suggest that sex chromosome evolution may be more complex than previously thought. The concept of sexual antagonism (when there is a positive intersexual genetic correlation in trait expression but opposite fitness effects of the trait(s) in males and females) has become essential to our understanding of sex chromosome evolution. The goal of this proposal is to understand how the interacting effects of sexual antagonism, sex-linked genetic variation, and sex-specific selection shape the genetic architecture of complex traits. I will test the hypotheses that: 1) individual sexually antagonistic loci are common in the genome, both in separate-sexed species and in hermaphrodites, and drive patterns of sexual antagonism often seen on the trait level. 2) That the response to sex-specific selection in sex-linked loci is usually due to standing sexually antagonistic genetic variation. 3) That sexually antagonistic variation is primarily non-additive in nature. To accomplish this, I will use a combination of approaches, including sex-limited experimental evolution of the X chromosome and reciprocal sex chromosome introgression among distantly related populations of Drosophila, quantitative genetic analysis and experimental evolution mimicking the creation of a novel sex chromosome in the hermaphroditic flatworm Macrostomum, and analytical and simulation modeling. This project will serve to confirm or refute the assumption that trait-level sexual antagonism reflects the contributions of many individual sexually antagonistic loci, increase our understanding of the contribution of coevolution of the sex chromosomes to population divergence, and help provide us with a better general understanding of how genotype maps to phenotype.", "To": ["2021-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["678148"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 212 194,80"], "Project_Title": ["Island Diversity from an Eco-evolutionary Approach"], "Total_Cost": ["EUR 212 194,80"], "Country": ["Denmark"], "Project_ACR": ["IDEA"], "Technology_Description": "The science of island biogeography is currently undergoing a huge resurgence of interest, due mainly to the advent of novel sources of data, most notably on geological dynamics, climate-driven sea-level changes, remotely sensed climate, vegetation structure and topography, and, centrally, the phylogenetic relationships among species. This has paved the way for an understanding of how island geographical dynamics shape dynamics of species diversity and the evolution of clades, but has also opened up a whole range of unanswered questions: How has the emergence of islands affected evolution in clades? How does vegetation structure and topographic complexity shape patterns of diversity? What are the roles of cross-taxon interactions in governing these processes? And how do these patterns scale from the island to the community level?", "To": ["2018-03-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-03-15"], "Project_ID": ["707968"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["HUMANITAS UNIVERSITY"], "EU_Contribution": ["EUR 168 277,20"], "Project_Title": ["Transcriptional regulation by TBX18 in vascular development and disease"], "Total_Cost": ["EUR 168 277,20"], "Country": ["Italy"], "Project_ACR": ["TBX18"], "Technology_Description": "Mural cells (pericytes and vascular smooth muscle) enclose blood vessels and are critical for vascular homeostasis. Absence or malfunction of pericytes or vascular smooth muscle results in aneurysm formation in small or large blood vessels, respectively. Our previous work showed Tbx18 is selectively expressed in mural cells of multiple adult organs.", "To": ["2020-01-01, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-02"], "Project_ID": ["748035"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["LUNDS UNIVERSITET", "LUNDS UNIVERSITET"], "EU_Contribution": ["EUR 1 268 076"], "Project_Title": ["Discovery strategies for Dark Matter and new phenomena in hadronic signatures with the ATLAS detector at the Large Hadron Collider"], "Total_Cost": ["EUR 1 268 076"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["DARKJETS"], "Technology_Description": "The Standard Model of Particle Physics describes the fundamental components of ordinary matter and their interactions. Despite its success in predicting many experimental results, the Standard Model fails to account for a number of interesting phenomena. One phenomenon of particular interest is the large excess of unobservable (Dark) matter in the Universe. This excess cannot be explained by Standard Model particles. A compelling hypothesis is that Dark Matter is comprised of particles that can be produced in the proton-proton collisions from the Large Hadron Collider (LHC) at CERN. ", "To": ["2021-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-02-01"], "Project_ID": ["679305"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["LUNDS UNIVERSITET", "LUNDS UNIVERSITET"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Linking Cardiometabolic Disease and Cancer in the Level of Genetics, Circulating Biomarkers, Microbiota and Environmental Risk Factors"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["BIOMENDELIAN"], "Technology_Description": "Cardiovascular disease (CVD), type 2 diabetes (T2D) and obesity, collectively referred to as cardiometabolic disease, together with cancer are the major morbidities and causes of death. With few exceptions, research on cardiometabolic disease and cancer is funded, studied and clinically applied separately without fully taking advantage of knowledge on common pathways and treatment targets through interdisciplinary synergies. The purpose of this proposal is to reveal causal factors connecting and disconnecting cardiometabolic diseases and cancer, and to understand interactions between gut microbiota, host diet and genetic susceptibility in a comprehensive prospective cohort study design to subsequently allow design of intervention strategies to guide more personalized disease prevention.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["649021"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["DANMARKS TEKNISKE UNIVERSITET", "TECHNISCHE UNIVERSITAET MUENCHEN", "TECHNISCHE UNIVERSITEIT EINDHOVEN", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "MEDIZINISCHE UNIVERSITAET WIEN", "NKT PHOTONICS A/S", "PHILIPS ELECTRONICS NEDERLAND B.V.", "FEMTOLASERS PRODUKTIONS GMBH", "ITHERA MEDICAL GMBH", "EKSPLA UAB"], "EU_Contribution": ["EUR 3 902 716,44"], "Project_Title": ["Multimodal, Functional Bio-Photonic Imaging"], "Total_Cost": ["EUR 3 902 716,44"], "Country": ["Denmark", "Germany", "Netherlands", "Switzerland", "Austria", "Denmark", "Netherlands", "Austria", "Germany", "Lithuania"], "Project_ACR": ["FBI"], "Technology_Description": "FBI fosters education of ESRs on an emerging, multimodal imaging platform and its translation into clinical and biological applications. In FBI, 15 ESRs are trained at world-leading European academic institutions and companies, thus forming strong interdisciplinary relations between industry, technical sciences and clinical end-users.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-10-01"], "Project_ID": ["721766"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["LUNDS UNIVERSITET", "LUNDS UNIVERSITET"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Detailed Characterization of Spray Systems using Novel Laser Imaging Techniques"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["Spray-Imaging"], "Technology_Description": "The multiple scattering of light is a complex phenomenon, commonly encountered but rarely desired. In imaging it induces strong blurring on the recorded photographs, limiting the range of applicability and accuracy of modern optical instruments. A typical example concerns the laser diagnostics of spray systems. The PI has revealed in 2008 a technique based on structured illumination with the important capability to remove the contributions from multiple light scattering, allowing the unique possibility of visualising through dense sprays. Based on this acquired knowledge, the aim of this proposal is to develop and apply three novel imaging techniques for the complete characterizations of spray systems:", "To": ["2020-02-29, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-03-01"], "Project_ID": ["638546"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["CHERRY BIOTECH"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Standard Collagenous ORgans-on-chip ENvisaging Advanced Biological Researches"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["SeCtOR ENABleRs"], "Technology_Description": "SeCtOR ENABleRs aims to develop a convenient kit for the production of partially customizable organs-on-chip. The main motivations that lead us to get involved in this effort are to provide the scientific community of an easy-to-use, economically convenient and standardized microfluidic platform. This is expected to facilitate and promote the diffusion of advanced 3D cell culture systems in routine analyses and make results obtained from different experiences/laboratories more comparable. In this view we envisage possible applications in the field of stem cell biology, personalized medicine, toxicology as well as advanced pre-clinical trials. The kit main components are an ad hoc designed thermoplastic chip and a set of collagenous formulations. The chip design will allow the integration of a thermo-controller device compatible with live cell imaging techniques. A biomimetic approach and a cell-friendly crosslinking strategy will allow to control the composition and the mechanical properties of the collagenous formulations, thus approaching the complexity of natural cell environment. The flexibility of the kit will be demonstrated by obtaining vascularized neuronal and bone models using commercially available cells. Although some risky steps areforeseeable, the innovation in this project is more represented by the concept of organs on chip platform standardization than in significant disruptive breakthroughs. We are convinced that the accessibility to a convenient, standardized and flexible platform is the key to exploit the huge potentialities demonstrated by microfluidics organs on chip. The implementation of the proposed multidisciplinary work plan in an industrial environment will contribute to obtain unconventional complementary skills; understanding of the industrial perspective and needs and will finally guarantee the full exploitation of the project outcomes by establishing future SME/academics collaboration projects.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-SE - Society and Enterprise panel"], "Coordinated_in": ["France"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-09-01"], "Project_ID": ["752277"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE FRANCIS CRICK INSTITUTE LIMITED", "THE FRANCIS CRICK INSTITUTE LIMITED"], "EU_Contribution": ["EUR 2 118 431"], "Project_Title": ["Telomere metabolism in Genome Stability and Disease"], "Total_Cost": ["EUR 2 118 431"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["TelMetab"], "Technology_Description": "Telomeres are specialised nucleoprotein structures that protect chromosome ends from degradation and promiscuous DNA repair activities. Critically short telomeres give rise to Dyskeratosis Congenita and Hoyeraal-Hreidarrson Syndrome (HHS), highlighting the clinical importance of maintaining telomeres. Telomeres also progressively shorten with each cell division, eventually triggering cellular senescence. Although telomerase is able to extend telomeres to solve the \u201cend replication problem\u201d, its re-expression is a major route to cancer cell immortalization. Hence, telomeres and telomerase must be subject to exquisite regulation to maintain telomere homeostasis and organismal function. We have previously implicated the Fe-S helicase RTEL1 in maintaining vertebrate telomeres, which is frequently mutated in HHS. In this ERC proposal, we will employ proteomic methods, super-resolution microscopy, biochemistry and genetic approaches to: i) investigate why telomerase is the cause of telomere dysfunction in the absence of Rtel1, ii) how RTEL1 is controlled during the cell cycle, and iii) how this process is compromised by Rtel1 mutations in HHS. By establishing quantitative PICh to interrogate telomere composition in unprecedented detail, we have uncovered an unappreciated compensation between RTEL1 and ATRX at telomeres and also identified SLX4IP as a key regulator of telomere recombination, which we will characterize at a mechanistic level. We will extend our expertise in quantitative PICh and genome-wide CRISPR screens to identify novel factors that respond to or are lost from telomeres as a result of: i) induction of DNA damage at telomeres, ii) inhibition of p97 segregase, and iii) the onset of senescence. Our proposal will lead to a greater understanding of the causes/consequences of telomere dysfunction in multiple contexts, the factors that mitigate these effects to maintain telomere homeostasis and how these processes are compromised in human diseases.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["742437"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["INSTYTUT LACZNOSCI PANSTWOWY INSTYTUT BADAWCZY"], "EU_Contribution": ["EUR 134 462,40"], "Project_Title": ["Open-source freeware for fiber optic communication and sensing simulations"], "Total_Cost": ["EUR 134 462,40"], "Country": ["Poland"], "Project_ACR": ["SIMFREE"], "Technology_Description": "To meet the constantly increasing traffic in optical networks due to ever growing requirements of society spectral efficiency should be increased by using, an advanced modulation formats and reduced channel spacing. This results in increased spectral power density and interferences with an adjacent channels. Furthermore, dynamic links switching in the network is foreseen. All this makes the physical layer simulations an important task in network modeling, helping to optimise the transmission range of individual optical paths. The commercial tools designed to simulate fiber optic systems, are rather expensive and there is no simpler alternative software of this type. ", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Poland"], "Activity": ["Research Organisations"], "From": ["2017-07-01"], "Project_ID": ["748767"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["AARHUS UNIVERSITET"], "EU_Contribution": ["EUR 200 194,80"], "Project_Title": ["Gregory Nazianzen's methodeology of the theological arguing"], "Total_Cost": ["EUR 200 194,80"], "Country": ["Denmark"], "Project_ACR": ["Gregory"], "Technology_Description": "The objectives of the research project are to show how a strong focus on an early Christian author\u2019s use of classical rhetoric and philosophy (fx. Plato and Aristotle) can deepen our understanding of style and content of ancient Christian texts. This will be exemplified by detailed rhetorical and philological analyses of Gregory Naziansen\u2019s five theological orations. Modern literary theories of reception will be employed to illuminate how Gregory used classical rhetoric and philosophy. The research project will thus revitalize traditional methods of classical philology and combine them with modern literary theories. Further I will study the composition of the cycle of the five theological orations arguing that they are written as a coherent whole. Each oration will also be studied separately clarifying which rhetorical and philosophical methods and techniques the author has used, which connections with classical pagan and early Christian (Alexandrian school) traditions they show, and which kind of theological arguing (positive and negative theology) they are characterized by. The proposed research will at the same time serve as a model for how philological and rhetorical analyses and theories of reception can be used as a tool for analyzing other ancient Christian texts.", "To": ["2017-07-29, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-07-01"], "Project_ID": ["660894"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["TECHNISCHE UNIVERSITEIT EINDHOVEN", "UNIVERSITEIT UTRECHT", "UNIVERSITEIT GENT", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "HELSINGIN YLIOPISTO", "UNIVERSITE DE BORDEAUX", "CHEMCONNECTION BV", "STICHTING KATHOLIEKE UNIVERSITEIT"], "EU_Contribution": ["EUR 3 894 543,36"], "Project_Title": ["Nanomedicine: an integrative approach"], "Total_Cost": ["EUR 3 894 543,36"], "Country": ["Netherlands", "Netherlands", "Belgium", "United Kingdom", "Finland", "France", "Netherlands", "Netherlands"], "Project_ACR": ["NANOMED"], "Technology_Description": "Nanomedicine (NM) is regarded as one of the most promising applications of nanotechnology, as it would allow the development of tailored therapies, with a high level of selectivity and efficacy. Although much research has been performed over the past decades, translation from academia to commercial application remains disappointingly low. Reasons that explain the current moderate success of NM are: (1) promising preclinical results are often poorly predictive for clinical safety and effectiveness, (2) the efficient, scalable and reproducible GMP production of nanocarriers has proven to be challenging and (3) regulatory frameworks are not yet fully equipped to efficiently facilitate the introduction of novel nanomedicines. These obstacles are often encountered since the developmental process from carrier design to clinical assessment is performed by a range of scientists from different backgrounds who have difficulty interacting and communicating with each other to clearly understand the necessary design criteria and the scope and limitations of NM.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["676137"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["UNIVERSITAET LEIPZIG"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Marine Stratocumulus Cloud Cover and Climate"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["MSCCC"], "Technology_Description": "Global climate change is forced by the balance of the warming due to anthropogenic greenhouse gases and the cooling due to anthropogenic aerosol pollution particles. Among these, the cloud-mediated aerosol radiative forcing is by far the main component of the uncertainty. Marine stratocumulus clouds in particular play a decisive role due to their very large net effect on the Earth's radiative energy budget. Stratocumulus clouds occur in the two main regimes of open and closed cells that differ significantly by their cloud cover, and thus by their radiative effect. The main hypothesis of this proposal is that anthropogenic aerosols exert a substantial radiative forcing via their potential to impede or delay the transition from closed to open cells marine stratocumulus, and that this presumably un-buffered effect is not accounted for in forcing estimates by current climate models.", "To": ["2018-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-04-01"], "Project_ID": ["703880"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITA CA' FOSCARI VENEZIA"], "EU_Contribution": ["EUR 180 277,20"], "Project_Title": ["Visualising Engineered Landscapes: an archaeological approach to unlock environmental resilience and sustainability in antiquity"], "Total_Cost": ["EUR 180 277,20"], "Country": ["Italy"], "Project_ACR": ["VEiL"], "Technology_Description": "Contemporary anthropogenic landscapes were shaped by centuries of human action. Land surveying and division were the first forms of widespread landscape engineering performed by pre-industrial societies. Among those, the most complex was unquestionably the Roman Centuriation, which still characterise the rural landscapes of many European countries. Notwithstanding its impact on modern European land organisation, the principles underlying the design approach used by Roman land commissioners are still largely ambiguous. The proposed project thus aims to illuminate the process of landscape engineering undertaken in antiquity by the Roman surveyors and contribute to the discipline of landscape engineering by injecting a new body of evidence into the debate about past land division and design in order to inform models of sustainable practice for contemporary landscape management.", "To": ["2017-07-19, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-07-20"], "Project_ID": ["656337"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["HOEGSKOLAN I BORAS", "THE ROYAL COLLEGE OF ART", "HERIOT-WATT UNIVERSITY", "VILNIAUS DAILES AKADEMIJA", "UNIVERSITAT DER KUNSTE BERLIN", "TECHNISCHE UNIVERSITEIT EINDHOVEN", "PHILIPS ELECTRONICS NEDERLAND B.V.", "AB LUDVIG SVENSSON", "PHILIPS LIGHTING B.V."], "EU_Contribution": ["EUR 3 856 700,88"], "Project_Title": ["ArcInTex ETN"], "Total_Cost": ["EUR 3 856 700,88"], "Country": ["Sweden", "United Kingdom", "United Kingdom", "Lithuania", "Germany", "Netherlands", "Netherlands", "Sweden", "Netherlands"], "Project_ACR": ["ArcInTex ETN"], "Technology_Description": "A fundamental challenge in design research today is to define the design programs that suggest how we can turn our days scientific knowledge and technical development into design for new forms of living that will provide foundations for a more sustainable way of life. Through a cross-disciplinary and cross-national network in architecture, textiles and interaction design the consortium will build and train a new research community to take on this challenge in practice based design research from a broader perspective, in collaboration between academia and the private sector, combining areas of design where Europe by tradition have a very strong position. The proposed ArcInTex ETN aims to strengthen the foundations of design for new forms of more sustainable ways of living by connecting architecture, textiles and interaction design in a training network for Early stage researchers. Deepening connections between textile, architectural and interaction design will open up for new reflective foundations of the design for living in an age of technological innovations, designing for adaptive and responsive environments connecting the scales of the body, the interior and the building. By a combination of in depth specialization, collaborative project work training and company internship, the ESRs of the network will form a highly trained avant-garde ready to take on fundamental challenges both in academia and in the private sector building their work practice on new ideas of material thinking and design thinking with emphasis on sensitive design expressions for reflective living. By strong focus on practice based design research the ETN will contribute to further establish design research at a level similar to that of engineering science in areas of special importance for the design of our future ways of living, which is crusial for academia and private sector collaboration in the given areas of design research.", "To": ["2018-12-31, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["642328"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["GOETEBORGS UNIVERSITET"], "EU_Contribution": ["EUR 185 857,20"], "Project_Title": ["Permafrost thaw \u2013 decadal responses to climate change"], "Total_Cost": ["EUR 185 857,20"], "Country": ["Sweden"], "Project_ACR": ["PERMTHAW"], "Technology_Description": "Permafrost soils contain approximately 1672 Petagram carbon (C), twice the amount of the current atmosphere, and constitute 50% of the world\u2019s belowground C pool. Along with the current change in climate these high latitudinal soils experience increased temperatures, more than any other region, with permafrost degradation as a result. Such thaw of permafrost releases ancient organic matter that has been stored in the frozen soils for centuries. Following microbial degradation, this organic matter can be released to the atmosphere as carbon dioxide (CO2), methane (CH4) and nitrous oxide (N2O), further influencing the climate systems. Thus, a changed climate leads to server alterations of the carbon (C) and nitrogen (N) balance in Arctic and high altitude ecosystems. However, research up to today has mostly focused on the impact of permafrost thaw and the time horizon immediately following this degradation. ", "To": ["2018-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["657627"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 246 668,40"], "Project_Title": ["Evolution of the social brain: How social complexity affects individual cognition in ants"], "Total_Cost": ["EUR 246 668,40"], "Country": ["France"], "Project_ACR": ["BrainiAnts"], "Technology_Description": "This project aims to answer a significant open question in evolutionary neurobiology: how social complexity shapes the brain structure, its associated metabolic costs, and the behavioural capability of individual members of a society. The Social Brain Hypothesis proposes that the complexity of living in group influences encephalization in vertebrates, but this theory has not been critically tested in invertebrate species. Social insects such as ants have miniaturized brains that nevertheless support highly coordinated collective behaviour and striking individual cognitive abilities. This collective behaviour produces an \u201cexternalized\u201d distributed processing of information that may reduce energetic expenses in individual brains. ", "To": ["2018-07-31, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2015-08-01"], "Project_ID": ["660976"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["ITA-SUOMEN YLIOPISTO"], "EU_Contribution": ["EUR 267 793,20"], "Project_Title": ["An interdisciplinary approach to uncover the mechanisms of progression of cartilage damage at the cellular and tissue levels"], "Total_Cost": ["EUR 267 793,20"], "Country": ["Finland"], "Project_ACR": ["INpaCT"], "Technology_Description": "Joint injuries are very frequent, especially among young people. Such injuries seldom heal and over time can lead to cartilage degeneration and ultimately osteoarthritis. Although, it is generally assumed that excessive mechanical loading post-injury can cause or accelerate the progression of cartilage degeneration, the precise mechanisms involved in the pathological processes at different structural length scales are still not fully understood. Thus, novel approaches for understanding structure-function relationships from the cell to tissue level in both health and disease are necessary. The overall aim of this research is to investigate the mechanisms of cartilage damage progression at different levels of tissue organization. The novelty of this research lies in the highly interdisciplinary approach of combining an in vitro model of OA progression with the state-of-the-art materials testing devices, computational modeling and sophisticated microscopic, spectroscopic and molecular biology techniques to carefully assess the mechanics, structure, composition and gene expression on cell and tissue levels. The novel data obtained from this research will shed light on the key mechanobiological pathways by which cartilage cells maintain healthy tissue or mount a healing response following tissue injury and excessive loading. This project is conducted as an international collaboration between University of Eastern Finland, Kuopio, Finland and Massachusetts Institute of Technology, Cambridge, USA. This represents a unique opportunity to bring together the complementary skill sets of Dr. Florea, Dr. Korhonen\u2019s group and Prof. Grodzinsky\u2019s group, with their expertise in biomechanics, computational modeling, biochemistry and cartilage biology. The mutually beneficial collaboration between Europe and USA can advance the field of cartilage research with significant potential to provide novel strategies to reduce/prevent cartilage degeneration for patients in Europe and beyond.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["702586"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITAET LEIPZIG"], "EU_Contribution": ["EUR 239 860,80"], "Project_Title": ["Modeling Common Ground"], "Total_Cost": ["EUR 239 860,80"], "Country": ["Germany"], "Project_ACR": ["ModelingCommonGround"], "Technology_Description": "Language is inherently ambiguous. The meaning of words and sentences depends on the identity of the communicative partners and the nature of the context. In simple behavioral experiments children and adults can use a wide variety of social-contextual cues (jointly known as \u201ccommon ground\u201d) to interpret ambiguous utterances. But this limited empirical evidence \u2013 especially in the developmental context \u2013 does not live up to the theoretical importance of common ground: In theory, common ground is not only involved in online language use but it is also a necessary prerequisite to learn language in the first place. Studying the development of children\u2019s ability to form and use common ground is therefore crucial to understand the psychological foundation of language. It is still unknown how both adults and children integrate different social-contextual cues in complex, naturalistic interactions. Bayesian modeling provides a mathematical framework for formalizing theoretical assumptions about this interaction and deriving quantitative predictions about new experimental situations.", "To": ["2020-09-10, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-11"], "Project_ID": ["749229"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Impact of Intrapartum Antimicrobial Prophylaxis as an early determinant in Microbiome Development"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["IAPEMIDE"], "Technology_Description": "During the last decades, changes in diet and lifestyle have increased the risk of non-communicable diseases in the western countries. It is known that once they are established in the childhood, they continue into adult life with the associated negative impact on health, quality of life and health care costs. The correct establishment of the intestinal microbiota (IM) at the beginning of life plays a key role in health, reducing risk of chronic disease. Some factors affecting this process have been studied; however, other like the intrapartum antimicrobial prophylaxis (IAP), in spite of been present on over 30% of total deliveries, have been much less studied. It is already known that at least 11 types of broad-spectrum antibiotics cross the placenta and reach the foetus. Given the increasingly evident relationship between early microbiota, later disease risk and the rising worries regarding antimicrobial resistances, there is an urgent need to assess the potential adverse consequences of IAP in the establishment of the IM and resistome. This project will be the first to study mechanisms orchestrating the impact of IAP on the neonatal IM establishment. The objectives are: identify the alterations induced by IAP in the neonatal IM development; identify the antibiotic resistance genes that the IM carried as consequence of IAP; study the potential role of infant feeding in the modulation of the microbiota after IAP administration and design of specific dietary strategies for minimising the impact of IAP on the IM establishment. Moreover, if the breast-milk exerts a protective role, it would help to strengthen the maternal breast-feeding recommendations. Following this study, doctors will be better able to address the consequences to make knowledge-based decisions about IAP treatment in those situations where it is not extremely mandatory. Besides, the present project will represent a worthy opportunity for the applicant to improve her research competences and career.", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-08-01"], "Project_ID": ["749255"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAET BERN"], "EU_Contribution": ["EUR 175 419,60"], "Project_Title": ["The cryptic path of tumor-microenvironment interactions in prostate cancer"], "Total_Cost": ["EUR 175 419,60"], "Country": ["Switzerland"], "Project_ACR": ["STOPCa"], "Technology_Description": "In the developed countries, prostate cancer is the second leading cause of cancer-associated death in men, with a predicted rate of 10.9/100.000 men in Europe in 2016. Mortality results when prostate cancer has spread to other organs (metastasis, particularly to the bone). Prostate cancer prognosis and follow-up is mainly performed with routine blood test (prostate specific antigen levels). However, the low/high risk of metastasis for individual patients cannot always be accurately assessed due to tumor heterogeneity and differential rate of tumor progression. Thus, a more thorough understanding of the metastatic processes is needed. ", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["748836"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["LATVIJAS UNIVERSITATE"], "EU_Contribution": ["EUR 145 904,40"], "Project_Title": ["Multimodal Spectral Imaging for Canine Skin Erythema Estimation: from the Lab to the Clinic \u2013 DogSPEC"], "Total_Cost": ["EUR 145 904,40"], "Country": ["Latvia"], "Project_ACR": ["DogSPEC"], "Technology_Description": "In this action, we propose a novel portable and cost-effective multispectral device for smartphones that will monitor dog skin health in terms of erythema. Up to 50-% of European households own a dog, and the five of the ten most common reasons for a veterinary visit can be reflected in erythematous skin. Currently, there are no methods for the objective estimation of the intensity of erythema. In this action, we will first develop multispectral near-infrared device for the detection of extra absorption peaks of hemoglobin. In order to learn about hemodynamics, we will continue with objective measurements of capillary refill time. Then, we will develop a device for the multimodal acquisition of visible multispectral and fluorescence images and near-infrared multispectral data. This will serve for an estimation of erythema intensity by calculating an erythema index. The latter will be validated using existing dermatological tests (e.g. CADESI) in order to study whether erythema index can replace erythema visual assessment. Finally, we will investigate if there is any correlation between erythema and underlying causes (tumors). The proposed methods can simplify and improve current diagnostic procedures in veterinary dermatology.", "To": ["2019-08-21, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Latvia"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-22"], "Project_ID": ["745396"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["STOCKHOLMS UNIVERSITET", "STOCKHOLMS UNIVERSITET"], "EU_Contribution": ["EUR 2 492 834"], "Project_Title": ["Earth Resilience in the Anthropocene (ERA)Integrating non-linear biophysical and social determinantsof Earth-system stability for global sustainabilitythrough a novel community modelling platform"], "Total_Cost": ["EUR 2 492 834"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["ERA"], "Technology_Description": "In 2015, the UN Sustainable Development Goals (SDGs) and the Paris Agreement on climate recognised the deteriorating resilience of the Earth system in the Anthropocene. Maintaining Earth in the interglacial state that enabled the world\u2019s societies to evolve over the past 12,000 years will require industrialised societies to embark on global-scale social transformations. Otherwise, there is a real risk of crossing tipping points in the Earth system triggering abrupt and irreversible changes. ", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["743080"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich"], "EU_Contribution": ["EUR 265 840,20"], "Project_Title": ["Multi-language text summarization"], "Total_Cost": ["EUR 265 840,20"], "Country": ["Switzerland"], "Project_ACR": ["ML-TEXTSUM"], "Technology_Description": "In our daily life, we are submerged by huge amounts of text, coming from different sources such as emails, news, reports, and so on. The availability of unprecedented volumes of data represents both a challenge and an opportunity. On one hand, it can lead to information overload, a phenomenon that limits one\u2019s capacity to understand an issue and act in the presence of too much information. On the other hand, the effective harnessing of this information has undeniable economical potential. Furthermore, In the European context, special needs to be put to multilingualism to guarantee global access to high quality information.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["748900"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ROYAL COLLEGE OF SURGEONS IN IRELAND", "TECHNISCHE UNIVERSITAET DRESDEN", "UNIVERSITE DU LUXEMBOURG", "KATHOLIEKE UNIVERSITEIT LEUVEN", "RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG", "ONCOMARK LIMITED", "UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN", "OPTIMATA LTD", "KRAEFTENS BEKAEMPELSE", "PROTATOUANS - ETAIREIA EREYNAS VIOTECHNOLOGIAS MONOPROSOPI ETAIREIA PERIORISMENIS EYTHINIS", "UNIVERSITAET STUTTGART", "UNIVERSITAETSKLINIKUM AACHEN"], "EU_Contribution": ["EUR 3 583 870,17"], "Project_Title": ["Exploiting MELanoma disease comPLEXity to address European research training needs in translational cancer systems biology and cancer systems medicine"], "Total_Cost": ["EUR 3 583 870,17"], "Country": ["Ireland", "Germany", "Luxembourg", "Belgium", "Germany", "Ireland", "Ireland", "Israel", "Denmark", "Greece", "Germany", "Germany"], "Project_ACR": ["MEL-PLEX"], "Technology_Description": "Novel treatment options and associated personalised, patient-tailored therapies need to be explored and developed for highly heterogeneous and chemotherapy resistant cancers, such as malignant melanoma. This can only be achieved by industry-academia collaborations in newly emerging, innovative research disciplines such as translational cancer systems biology and systems medicine. These disciplines and the associated European training needs provide the foundation for the MEL-PLEX ETN. MEL-PLEX aims to understand the network-level and multi-scale regulation of disease-relevant signalling in melanoma through a combination of quantitative biomedical and computational research approaches that go significantly beyond the current state-of-the-art. Coordinated by the RCSI Centre for Systems Medicine, MEL-PLEX will train 15 early stage researchers through a highly interdisciplinary and intersectoral research training programme. MEL-PLEX comprises 11 beneficiaries and 7 partner organisations from 11 countries, including European and international leaders in personalised melanoma therapy, melanoma systems biology and cancer systems medicine. MEL-PLEX aims to (i) achieve an unmatched depth of molecular and mechanistic disease understanding, (ii) will exploit this knowledge to develop and validate predictive models for disease progression, prognosis and responsiveness to current and novel (co-)treatment options, and (iii) will provide superior and clinically relevant tools and biomarker signatures for personalising and optimising melanoma treatment. The MEL-PLEX ETN addresses current needs in academia and the private sector for researchers that have been trained in an environment that spans across biology, medicine and mathematics, that can navigate confidently between clinical, academic and private sector research environments, and that have developed an innovative and creative mindset to progress research findings towards applications.", "To": ["2018-11-30, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2014-12-01"], "Project_ID": ["642295"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["SOFIISKI UNIVERSITET SVETI KLIMENT OHRIDSKI", "SOFIISKI UNIVERSITET SVETI KLIMENT OHRIDSKI"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Bottom-up Energy Efficient Emulsification and Structured Materials"], "Total_Cost": ["EUR 150 000"], "Country": ["Bulgaria", "Bulgaria"], "Project_ACR": ["ShipShape"], "Technology_Description": "Bottom-up Energy-Efficient Emulsification and Structured Materials Fabrication.", "To": ["2018-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Bulgaria"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["766656"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["VIB"], "EU_Contribution": ["EUR 160 800"], "Project_Title": ["Nanobody-enabled Structural Investigation of a G Protein-Coupled Receptor-Arrestin Complex"], "Total_Cost": ["EUR 160 800"], "Country": ["Belgium"], "Project_ACR": ["NESIAC"], "Technology_Description": "Although many thousands of transient protein-protein interactions (PPIs) are known, there is a disturbing paucity of high-resolution structures of the resulting complexes and the difficulties involved in experimentally determining these atomic structures remain essentially unaddressed.", "To": ["2017-06-30, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Belgium"], "Activity": ["Research Organisations"], "From": ["2015-07-01"], "Project_ID": ["660753"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSIDAD COMPLUTENSE DE MADRID"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["The Kurds in Syria: A complex interplay between local, regional and transnational"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["ROJAVA"], "Technology_Description": "While extremely graphic images from the Syrian civil war appearing at the world media, smiling young Kurdish female guerrillas at the cover of magazines such as Elle, Marie Claire presented another picture. Kurdish fighters have become driving forces in offensives against ISIS and gained worldwide news coverage. However, the story of the Kurds in Syria is more than this.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["748155"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KAROLINSKA INSTITUTET"], "EU_Contribution": ["EUR 185 857,20"], "Project_Title": ["Dissecting the human microbiota-macrophage-innate lymphoid cell crosstalk in the lung"], "Total_Cost": ["EUR 185 857,20"], "Country": ["Sweden"], "Project_ACR": ["MICRO-MACRO-ILC"], "Technology_Description": "It is poorly understood how macrophages interact with other cells and commensal microbes (microbiota) to achieve the balance between barrier immunity and tissue homeostasis in the lung. Novel experimental systems are required to investigate the interaction between macrophages, innate lymphoid cells (ILC), and the microbiota since the immune system, inflammatory responses, and microbiota differ between mice and humans. However, studies in humans are limited by ethical constraints. To overcome this limitation, I will use mice with a human immune system (humanized mice) that are colonized with a human microbiota. The supervisor Dr. Willinger has drastically improved humanized mice by providing critical human factors through knock-in gene replacement. Using this unique tool, I will test the hypothesis that signals from the human microbiota regulate lung immune function through effects on alveolar macrophages and ILC and pursue the following objectives: (1) Define the role of human monocytes/macrophages in the homeostasis of lung ILC; (2) Determine how the human microbiota regulates lung macrophages and ILC; (3) Dissect the role of human monocytes/macrophages in lung inflammation. To achieve these aims, I will employ the state-of-the-art model to reconstitute the human lung immune system and microbiota in the mouse. I will deplete human alveolar macrophages and monocyte subsets to determine how these cells regulate ILC differentiation and lung inflammation. This will be complemented by studies in germ-free humanized mice colonized with a human lung microbiota to investigate immune regulatory effects of the local microbiota. The project will generate critical new insights into the human microbiota-macrophage-ILC crosstalk that cannot be obtained with other experimental approaches. My multidisciplinary approach involving humanized mice, immunology, and germ-free studies has the potential to discover novel approaches to treat human lung disease.", "To": ["2018-11-30, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-12-01"], "Project_ID": ["701258"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["KAROLINSKA INSTITUTET"], "EU_Contribution": ["EUR 185 857,20"], "Project_Title": ["Novel Resolvin D3: its Role and Actions in the Resolution of Aortic Valvular Inflammation and Stenosis"], "Total_Cost": ["EUR 185 857,20"], "Country": ["Sweden"], "Project_ACR": ["RvD3-RAVIS"], "Technology_Description": "Aortic valve stenosis is a progressive inflammatory disorder with poor prognosis if left untreated. Currently the only available treatment is invasive surgical replacement of the valve, therefore new therapeutic strategies are needed. Resolution of inflammation is an active process orchestrated by endogenous specialized proresolving lipid mediators (SPM). These include the resolvins that actively promote catabasis via their potent actions in anti-inflammation, proresolution, tissue regeneration and pain reduction. Recently the complete stereochemistry of resolvin D3 (RvD3) was established. Given its highly potent anti-inflammatory and proresolving actions in murine models and with human cells its role and actions in aortic stenosis (AS) remains to be uncovered. Thus, a goal of this proposal is to elucidate endogenous resolution programs in human aortic valves and define the role and action of RvD3 in AS and calcification. To address this the candidate will employ LC-MS-MS based LM metabololipidomics combined with clinically relevant parameters as well as biochemical and cellular assessments in samples from AS patients. In addition, RvD3 will be used as treatment in a novel preclinical model of murine AS. Implementation of the proposed project will maintain and enhance the candidate\u2019s position at the forefront in the field of resolution biochemistry with advances into valvular pathology. Unraveling the role of RvD3 and resolution programs in aortic inflammation and resolution may enhance current understanding of the molecular mechanism contributing to chronic cardiovascular inflammation and introduce a novel concept for the pathology AS. Furthermore, it may lead to novel therapeutic strategies with a potential to slow or halt the hemodynamic progression of stenosis via turning on resolution programs.", "To": ["2017-10-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-11-01"], "Project_ID": ["656817"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE", "LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["That Special First Time - Boosting Turnout and Satisfaction amongst First Time Voters"], "Total_Cost": ["EUR 150 000"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["FIRSTTIME"], "Technology_Description": "\"FIRSTTIME is dedicated to generating new unique instruments that Election Management Bodies (EMB) worldwide can use to organise a bespoke electoral experience for first time voters and increase their satisfaction and turnout. We will partner with EMBs to test them in real elections. ", "To": ["2017-06-30, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2015 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["680486"], "Call_for_Proposal": ["ERC-2015-PoC"]}, -{"Partners": ["LUNDS UNIVERSITET"], "EU_Contribution": ["EUR 185 857,20"], "Project_Title": ["The epigenetic basis of early-life effects in a wild bird exposed to urban environmental stress"], "Total_Cost": ["EUR 185 857,20"], "Country": ["Sweden"], "Project_ACR": ["URBANEPIGENETICS"], "Technology_Description": "The impact of urbanisation on wildlife is of increasing global concern. It is well known that exposure to urban environmental stressors increases oxidative stress. More recently, exposure to pollutants has been shown to directly modify the epigenome, via DNA methylation, in humans. Oxidative stress may be a key mechanism mediating epigenetic modifications in response to pollutant exposure and thereby influencing development, disease resistance and ageing. This multidisciplinary project outlines the first study to date of the epigenetic basis of early-life effects in a wild bird exposed to urban environmental stress. Early-life stress exposure can have profound effects on phenotypic development and long-term fitness. Epigenetic mechanisms are influenced by environmental cues during development and therefore may mechanistically link developmental conditions with later-life performance. Using urban and rural populations of birds, we will perform experimental studies in the field and lab to examine whether increased oxidative stress during development modifies patterns of global and gene-specific DNA methylation and thereby alters genome stability (via DNA damage and telomere attrition) and expression of antioxidant genes. To achieve this, we propose a new framework to explain how the modification of DNA methylation and telomere length may be linked and decoupled by the direct and indirect effects of oxidative stress at different stages during development. Pilot data support this framework. This will enable us to disentangle the mechanistic relationships between exposure to urban stressors, oxidative stress, DNA methylation and telomere dynamics during development and the consequences for growth and survival in an altricial bird species. The project has implications for multiple EU policies and H2020 focus areas. By combining the researcher\u2019s existing expertise with new skills and opportunities, the project will enhance career prospects and advance the research field.", "To": ["2017-03-31, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-04-01"], "Project_ID": ["659643"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["INSTITUT D'ESTUDIS ESPACIALS DE CATALUNYA FUNDACION"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["SmartClouds Orbital Dynamics and Control"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["SmartCloudsODC"], "Technology_Description": "This Action, entitled \u201cSmartClouds Orbital Dynamics and Control\u201d (SmartCloudsODC), will deliver radical new methodologies for orbital dynamics and control of multi-spacecraft systems to investigate new easy-accessible space-based products and services for Europe. Thanks to the advanced in Miniaturised Electromechanical Systems technology, a new class of low-cost, low-risk space missions - based on multiple cooperative elements - is arising. Assuming smart-clouds of vast numbers of femto-spacecraft, this Action will move from the classic - deterministic - celestial mechanics approach to a new paradigm in space mission design - based on stochastic analyses.", "To": ["2018-08-31, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2016-09-01"], "Project_ID": ["655534"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITAT DE VALENCIA", "UNIVERSITAT DE VALENCIA"], "EU_Contribution": ["EUR 1 827 375"], "Project_Title": ["A Chemical Approach to Molecular Spin Qubits: Decoherence and Organisation of Rare Earth Single Ion Magnets"], "Total_Cost": ["EUR 1 827 375"], "Country": ["Spain", "Spain"], "Project_ACR": ["DECRESIM"], "Technology_Description": "\"Coordination Chemistry and Molecular Magnetism are in an ideal position for the rational design of Single-Molecule Magnets which can be used as molecular spin qubits, the irreducible components of any quantum technology. Indeed, a major advantage of molecular spin qubits over other candidates stems from the power of Chemistry for a tailored and inexpensive synthesis of systems for their experimental study. In particular, the so-called Lanthanoid-based Single-Ion Magnets, which are currently the hottest topic in Molecular Magnetism, have the potential to be chemically designed, tuning both their single-molecule properties and their crystalline environment. This will allow the independent study of the different quantum processes that cause the loss of quantum information, collectively known as decoherence. The study of quantum decoherence processes in the solid state is necessary both to lay the foundations for next-generation quantum technologies and to answer some fundamental questions.", "To": ["2020-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-08-01"], "Project_ID": ["647301"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["UNIVERSITAT DE BARCELONA"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Multitarget compounds with therapeutic potential against Alzheimer disease: Design and in vitro studies"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["CHELALZ"], "Technology_Description": "This fellowship will provide a prolific researcher with an internationally competitive, multi-disciplinary research training at the Chemistry/Biology interface in an EU leading Bioinorganic chemistry team, preparing her to obtain her goal of a faculty position in the EU and her own research team in Medicinal Chemistry.", "To": ["2018-04-22, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["656820"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA", "UNIVERSIDADE DO MINHO", "UNIVERSITAT DE VALENCIA", "TECHNISCHE UNIVERSITAET MUENCHEN", "KATHOLIEKE UNIVERSITEIT LEUVEN", "UNIVERSITAT WIEN", "THE UNIVERSITY OF NOTTINGHAM", "Asociacion - Centro de Investigacion Cooperativa en Nanociencias - CIC NANOGUNE", "GRAPHENEA SA", "UNIVERSIDADE DE AVEIRO"], "EU_Contribution": ["EUR 2 962 661"], "Project_Title": ["Redesigning 2D Materials for the Formulation of Semiconducting Inks"], "Total_Cost": ["EUR 2 962 661"], "Country": ["Spain", "Portugal", "Spain", "Germany", "Belgium", "Austria", "United Kingdom", "Spain", "Spain", "Portugal"], "Project_ACR": ["2D-INK"], "Technology_Description": "2D-INK is targeted at developing inks of novel 2D semiconducting materials for low-cost large-area fabrication processes on insulating substrates through a new methodology, which will exceed the properties of state-of-the-art graphene- and graphene oxide based inks. Achieving this would represent an important step forward in the processing of 2D semiconducting materials and will provide the key parameters for fabricating the next generation of ultrathin electronic appliances.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-1-2014 - FET-Open research projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["664878"], "Call_for_Proposal": ["H2020-FETOPEN-2014-2015-RIA"]}, -{"Partners": ["LINKOPINGS UNIVERSITET", "POLITECNICO DI MILANO", "ALCATEL-LUCENT DEUTSCHLAND AG"], "EU_Contribution": ["EUR 1 043 441,28"], "Project_Title": ["Anticipatory Networking Techniques in 5G and Beyond"], "Total_Cost": ["EUR 1 043 441,28"], "Country": ["Sweden", "Italy", "Germany"], "Project_ACR": ["ACT5G"], "Technology_Description": "The rapid growth in mobile network data traffic contributed to the unprecedented speed of 4G LTE adoption, creating the need of sustainable capacity growth in next generation of wireless systems, namely 5G. A key success factor of 5G is network and management system design for flexibility by prediction and adaptation. To this end, anticipation is a promising new approach. By predicting and adapting to upcoming events at various time scales, an anticipatory network improving the operation quality and efficiency. First, network resources ranging from spectrum and buffers can be managed optimally to meet users\u2019 requirements. Second, network operators can jointly plan how to share infrastructures and resources to meet their demands at lower costs and better energy efficiency. ", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-EID - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-EID)"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-05-01"], "Project_ID": ["643002"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["UNIVERSITAT DE VALENCIA"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Spintronics with Non-Conventional 2D Materials"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["SPIN2D"], "Technology_Description": "Since the discovery of graphene in 2004, a member of the two-dimensional (2D) materials family, the amazing properties of these materials at the single layer level have attracted an enormous attention. Thanks to the plethora of available compounds, an extremely wide richness of properties covering the full range of electrical and magnetic behaviors is expected. For spintronics, the combination of 2D layers in designed multilayer stacks can be envisaged as a way to obtain highly optimized modules that, combined altogether, will allow the realization of fully 2D advanced spintronic devices (2D spinFETs, 2D spinOLEDs, 2D MTJs for 2D memories, etc..) leading towards their ultimate miniaturization and engineering. ", "To": ["2017-05-17, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-05-18"], "Project_ID": ["659378"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE", "LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE"], "EU_Contribution": ["EUR 1 276 880"], "Project_Title": ["Multinationals, Institutions and Innovation in Europe"], "Total_Cost": ["EUR 1 276 880"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["MASSIVE"], "Technology_Description": "Multinational Enterprises (MNEs) are key \u2018tectonic forces\u2019, shaping the \u2018mountains\u2019 in a far-from-flat world economic geography. In 2010, MNEs generated value added for approximately US$16 trillion accounting for more than a quarter of world GDP (UNCTAD, 2012). The progessive expansion of firms from emerging economies into multinational enterprises is unprecedented. Outflows of FDIs from developing economies reached the record level of $426 billion in 2012, corresponding to 31% of global outflows, up from 16% in 2007 (UNCTAD, 2013). ", "To": ["2020-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-06-01"], "Project_ID": ["639633"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE", "LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE"], "EU_Contribution": ["EUR 1 508 821,75"], "Project_Title": ["Constrained Democracy: Citizens\u2019 Responses to Limited Political Choice in the European Union"], "Total_Cost": ["EUR 1 508 821,75"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["EUDEMOS"], "Technology_Description": "National governments operate under the growing constraints of European integration that limit the choices they can offer citizens and the policy instruments they can use. Yet, despite the centrality of political choice to the functioning of electoral democracy, we know very little about the consequences of constrained political choices for citizens\u2019 engagement in democratic processes. Across Europe, an increasing number of citizens are supporting extreme parties or declining to take part in democratic elections. This project offers the first systematic examination of how the range and substance of political choices offered to citizens in the EU shape democratic perceptions and electoral behaviour. Understanding how citizens perceive and react to the growing constraints on domestic politics is crucial to a diagnosis of European democracy and for an evidence-based debate on reform of EU institutions. Building on the Principal Investigator\u2019s award-winning research on electoral democracy and extensive experience of designing and analysing cross-national surveys and experiments, this project is a pioneering study of the consequences of constrained democracy. It uniquely combines a large-N cross-national analysis of citizens\u2019 responses to mainstream party convergence and case studies of the \u2018emergency politics\u2019 of the Eurozone crisis with micro-level experimental work. This project aims to transform the study of citizens\u2019 democratic attitudes and behaviour by focusing on the importance of political choice. By developing and testing a theoretical model of heterogeneous citizen responses to the constrained political choice, the project provides insights into why citizens turn against mainstream parties or exit democratic processes altogether. This further allows EUDEMOS to develop proposals for how institutions can be designed to facilitate citizens\u2019 participation in and satisfaction with democratic processes in a multi-level European Union.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["647835"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Scientific Models, Fiction and Imagination"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SCIMOD"], "Technology_Description": "The project aims to systematically explore a novel approach to model-based reasoning drawing on the relationship between the debate on the nature of scientific models from philosophy of science and the debate on the nature of fiction from aesthetics. Many contemporary philosophers of science argue that learning with models involves a special cognitive function that they call \u201csurrogative reasoning\u201d or \u201cmodel-based reasoning\u201d. Understanding model-based reasoning can be divided into two subprojects: what model-systems are (SP1) and how knowledge about the model is converted/interpreted into knowledge about the target (SP2). Work within (SP1) will be driven by the hypothesis that scientific models are akin to the fictions of literature and the arts. Work within (SP2) will be driven by the hypothesis that interpretation is mediated by a representational relation converting a fact about the model system into a claim about the target system. The project relies on the normative and descriptive methodology of analytical naturalised philosophy of science, which focuses on examples and case studies. The project will benefit from the combination of Frigg\u2019s expertise in philosophy of science and modelling and of Salis\u2019 original specialization in the areas of aesthetics and the philosophy of fiction. Furthermore, we will collaborate with the experts from the CPNSS Philosophy of Physics project at LSE, with the decision theorists and social choice experts in the LSE\u2019s Choice Group and with the CATS (Centre for the Analysis of Time Series) group on climate models based at LSE. This study will lead to new insights into the nature of scientific modelling and model-based reasoning and it will open new lines of research by injecting a new and fresh perspective from aesthetics into philosophy of science.", "To": ["2017-09-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["654034"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["SCIENCE BUSINESS PUBLISHING LIMITED", "SCIENCE BUSINESS PUBLISHING LIMITED", "EVRO-SREDOZEMSKA UNIVERZA", "CIENCIA VIVA-AGENCIA NACIONAL PARA A CULTURA CIENTIFICA E TECNOLOGICA", "VISION2020 NETWORK LTD", "ASSOCIATION EUROPEENNE DES EXPOSITIONS SCIENTIFIQUES TECHNIQUES ET INDUSTRIELLES", "UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK", "EIRMA EUROPE AISBL", "SVEUCILISTE U ZAGREBU MEDICINSKI FAKULTET"], "EU_Contribution": ["EUR 958 759"], "Project_Title": ["ERC = ScienceSquared"], "Total_Cost": ["EUR 958 759"], "Country": ["United Kingdom", "United Kingdom", "Slovenia", "Portugal", "United Kingdom", "Belgium", "Ireland", "Belgium", "Croatia"], "Project_ACR": ["ScienceSquared"], "Technology_Description": "The ERC is a great success scientifically, and now wants to broaden its popular and political support. But it has a problem: Most EU citizens don\u2019t care about some Brussels agency they never heard of. The solution is in the ERC\u2019s mandate: frontier research. It has science \u2013 the cutting edge variety, that can capture the imagination, change the world and stimulate curiosity. We have seen the power of a fundamental science story elsewhere, and how it can focus attention on the institution behind it: the Higgs boson and CERN. It takes high scientific achievement, great story-telling, a tight focus, creative communications and a sustained effort to build a mass following in science. We believe the ERC can achieve this \u2013 to matter as the source of cool science, to students, investors, policy makers, researchers, and all citizens generally, in all 28 EU member-states and beyond. The ERC can invent science and mirror it back to society. In short, ERC = ScienceSquared.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-SUPPORT-2014 - ERC Support for novel ways to highlight the work funded by the ERC and reach out a wider public. "], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["United Kingdom"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Higher or Secondary Education Establishments", "Other", "Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["672302"], "Call_for_Proposal": ["ERC-2014-SUPPORT-1"]}, -{"Partners": ["UNIVERSITAT DE BARCELONA"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["The fate of black holes in high-energy physics -- exploring their dynamical instabilities"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["BHstabNL"], "Technology_Description": "Humankind has always been on a quest to uncover the secrets of our universe and \"detect the inmost force that binds the world and guides its course\". We intend to take important steps towards a more profound understanding of nature's mysteries by employing black holes (BHs).", "To": ["2018-09-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-29"], "Project_ID": ["655360"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK"], "EU_Contribution": ["EUR 187 866"], "Project_Title": ["Decoding Stress Resilience"], "Total_Cost": ["EUR 187 866"], "Country": ["Ireland"], "Project_ACR": ["DE-STRESS"], "Technology_Description": "Stress is a common feature of our lives yet some people respond to stress better than others, a concept known as resilience. There is a growing body of experimental data which has implicated several brain structures and molecular mechanisms. However to date there has been limited focus on the bed nucleus of the stria terminalis (BNST) and the mechanisms in this brain region which could be involved. One of several proteins expressed by the BNST, which is a key regulator of the stress response, is the pituitary adenylate cyclase-activating peptide (PACAP). But the expression of PACAP is under the control of stress-responsive nucleotides called miRNAs. Thus, there exists a complex system in the BNST which regulates the stress-response and hypothetically could be involved in mediating resilience. To test this hypothesis, the DE-STRESS project will conduct a series of experiments with the objectives of (i) determining whether PACAP expression in the BNST is different in states of resilience and susceptibility, (ii) identifying miRNAs that are differentially expressed in these states and which regulate PACAP expression and (iii) elucidating their functional effects on the stress response. Hence, the DE-STRESS project uses an innovative approach to decode the concept of stress resilience and will advance understanding of the pathophysiology of stress-induced disorders. Additional objectives of the project include dissemination and transfer of knowledge to relevant stakeholders, forming collaborations within academia and industry with a view to commercialising research findings as well as develop project management and career development skills of the applicant. In line with the Work Programme for the MSCA fellowships, the knowledge and competencies gained by the applicant will add to developing his potential to achieve professional maturity and leadership in the field so that he may continue to make significant contributions to society and the economy.", "To": ["2018-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-07-01"], "Project_ID": ["704995"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Adolescents, Parents and Digital Media: Looking for the pattern that dis/connects"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["AdoDigitFamX"], "Technology_Description": "This project will use a trans-disciplinary framework of social and developmental psychology and media and communications and the innovative methods of the First Person Perspective and Digital Ethnography to address existing gaps in research into the use of Information Communication Technologies, child development and family communication. Commenting upon research in the field, the recent report www.eukidsonline noted a prevalence of studies based on quantitative methods and a neglect of focus on mobile, convergent and emerging technologies. It also identified a persistent focus on risks and harm rather than opportunities and benefits and the lack of information on the role of adults, safety mediation and their effectiveness. This project fills these gaps by: (1) capturing the actual practices of adolescents with ICTs; (2) understanding how ICTs, family communication and parenting mutually shape one another; (3) exploring the opportunities and risks of ICTs for family and child development and the role of parents as safety mediators. A minimum of ten families with at least one adolescent child aged 13-16 will be recruited through Italian secondary schools to participate in the research which will involve data gathering via micro cameras (subcams) and video-interviews. Our innovative methods will provide new knowledge on: parents\u2019 and adolescents\u2019 individual and interpersonal practices in relation to ICTs; the goals, motives, representations and emotions underlying these practices and ICTs mediation processes in everyday family life. The implications of ICTs use for families and children\u2019s health will also be considered. The results will be disseminated to socio-educational and clinical agencies, policy makers, and the general public. The fellowship will be hosted by the Department of Social Psychology at the London School of Economics and Political Science, a pioneer in Digital Ethnography and co-supervised by the Department of Media and Communications.", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["660743"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITAT DE BARCELONA"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Collective Phenomena in dense Active Matter: phase transitions and non-equilibrium dynamics."], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["COLPHAM"], "Technology_Description": "The overall aim of the research activities presented in this proposal is to elucidate the general principles governing the physics of many-body systems of active particles when excluded-volume interactions compete with internal driving forces. We aim to reach a general understanding of this novel class of \u201cactive materials\u201d and give an answer to the following question: How are the structure of the liquid and solid phases, and their mechanical response to an applied deformation, affected by self-propulsion? Statistical mechanics can efficiently deal with a broad class of soft matter systems at thermal equilibrium. However, active matter evolves in a non-equilibrium manner, as it is made of elements which have their own source of motion, which demands a new conceptual framework to describe it. By combining numerical simulations and theoretical analysis of model systems, we intend to get new quantitative predictions that can be tested experimentally in suspensions of self-propelled colloids, active emulsions or dense assemblies of cells, and exploit our results to design and characterise novel materials through collaboration with experimental groups. The completion of this programme will represent a major contribution into this fast-growing field with direct applications in materials science and biophysics: the engineering of synthetic materials that mimic the behaviour of living matter is a major challenge of current science and technology.", "To": ["2017-07-14, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-07-15"], "Project_ID": ["657517"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITAT DE BARCELONA"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Fast Thermalization of the Quark-Gluon Plasma"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["FastTh"], "Technology_Description": "Understanding the properties of extreme phases of nuclear matter created in relativistic heavy ion collisions is one of the major challenges in theoretical physics. Matter under such extreme conditions was present in the very early universe and is nowadays produced in relativistic heavy ion collisions. In this proposal we address two questions that are central to the understanding of the very early stages of such collisions from the perspective of both strongly and weakly coupled field theory: What is the time-scale of the thermalization and why does it happen so fast?", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["658574"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITAT DE VALENCIA"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Tuning of 2D materials properties through controlled functionalization with opto-electroactive complexes"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["Terpy2DMat"], "Technology_Description": "Ultrathin two-dimensional nanosheets of layered transition metal dichalcogenides (TMDCs) are the fascinating materials for several applications in electronics, opto-electronics, spintronics, sensing, catalysis, energy storage and conversion, to name a few. The fields have witnessed huge attention world-wide in recent years. In spite of advancement of the 2D materials, there is a lack of proper chemical functionalization. Therefore, apposite functionalization of TMDCs to tune electronic charge and spin properties beyond current systems is extremely crucial. Herein, we propose chemical functionalization of 2D-TMDCs by optical and electroactive functional terpyridyl (tpy) complexes. The functional terpyridyl complexes offer numerous advantages including (i) much more robustness due to strong metal-to-ligand back bonding through [d\u03c0(M)-p\u03c0(L)] as compared to the organic ligands, (ii) versatile coordination modes, (iii) tunable, and reversible redox properties, and (iv) switchable metal-to-ligand charge-transfer (MLCT) band in the visible region. Through this functionalization we will be able to: ", "To": ["2019-01-15, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-01-16"], "Project_ID": ["706238"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["FUNDACIO INSTITUT DE RECERCA DE L'ENERGIA DE CATALUNYA"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Micro-Solid Oxide Fuel Cells based on highly catalytic ceramic oxide thin films nanostructures"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["Micro-SOLUTION"], "Technology_Description": "Solid Oxide Fuel Cells (SOFCs) are one of the most efficient and fuel flexible power generators. However, a great limitation on their applicability in portable devices arises from long start up times involving high energy consumption. A recent revolution based on the integration of SOFCs in mainstream silicon technology allows overcoming these drawbacks while opening new avenues for the use of fuel cells as uninterrupted power generators in mobile applications such as consumer electronics. Starting from the most recent breakthroughs of the hosting group, the Micro-SOLUTION project will be focused on improving the performance of \u00b5SOFCs at high temperatures (\u2265700 \u00baC) by developing thin film full-ceramic electrode materials with high catalytic activity. To achieve this goal, surface decoration of highly stable thin film nanostructured electrodes will be carried out. Further integration of the optimized electrodes in \u03bcSOFC cells will bring power densities above 500mW/cm2. The inter/multidisciplinary approach proposed in the Micro-SOLUTION project will allow the researcher acquiring new skills in Key Enabling Technologies such as nano- and micro-technology. Moreover, two different secondments in the Institute of Microelectronics of Barcelona and the company FAE will complement the researcher\u2019s training giving him a multisectoral point of view and a clear idea of transfer knowledge activities in the field of Solid Oxide Fuel Cells. Therefore, planned research and training activities in the Micro-SOLUTION project will re-enforce a position of professional maturity in research and will provide the researcher new career perspectives.", "To": ["2017-06-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2015-07-01"], "Project_ID": ["659270"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITAT DE BARCELONA"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Rotational effects on strongly gravitating systems with matter"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["REGMat"], "Technology_Description": "Black holes (BHs), where gravity is strongest in the universe, are the objects where we must confront the most extreme phenomena predicted by general relativity (GR) and extensions thereof. As for the majority of astrophysical bodies, BHs are typically spinning. However, addressing rotation in GR is notoriously difficult. Moreover, BHs are \u2018dirty\u2019: they are accompanied by clouds of gas or accretion disks, which introduce deviations from the known vacuum solutions. The complexity of the Einstein equations, taking into account the presence of matter and the rotation of spacetime, hampers attempts to model realistic BHs.", "To": ["2017-09-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["656882"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITAT DE BARCELONA"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["A novel isotope tool to assess nanoparticle toxicity in wetland plants"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["NANOREM"], "Technology_Description": "Nanoparticles (NPs), metal particles of less than 100nm, are increasingly emitted to the environment from a variety of anthropogenic sources. However, their toxic effects on living organisms, capacity to enter the food chain, and impact in environmental health are poorly understood. NANOREM is a research project aiming to provide the first comprehensive insight into the toxicity of zinc oxide (ZnO) nanoparticles in wetland plants. This information is essential to evaluate correctly the risk of releasing large quantities of NPs to the environment. In this project we will make use of cutting edge isotope techniques to trace the sources of NP pollution, and to understand how NPs might change the current paradigm of metal cycling and assimilation by plants. Furthermore, NPs will be synthesized from plants and plant extracts using novel methods, and fully characterized.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["704957"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Aryl amide metallofoldamersas selective saccharide sensors"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["RAMSES"], "Technology_Description": "Carbohydrate recognition is fundamental in varied biological processes such as cellular differentiation, cell\u2013cell interactions, immune defence and inflammatory response; consequently it plays key roles in tumour growth and metastasis, adhesion of viruses and bacteria to host cells and in immune and inflammatory disorders.", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2016-03-01"], "Project_ID": ["707071"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["KATHOLIEKE UNIVERSITEIT LEUVEN", "KATHOLIEKE UNIVERSITEIT LEUVEN", "STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Cancer treatment during pregnancy: from fetal safety to maternal efficacy"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Belgium", "Belgium", "Netherlands"], "Project_ACR": ["CRADLE"], "Technology_Description": "The evolution in drug regulation of the last 50 years has left pregnant women and their fetuses orphaned. This is particularly problematic for cancer during pregnancy, which raises a difficult and conflicting medical ethical decision process and which has recently become increasingly frequent. In 2012 we published the first prospective study indicating that antenatal exposure to cancer treatment can overall be considered safe. Building on this proof of concept, the current proposal wants to take a groundbreaking step towards developing a standard of care for cancer during pregnancy by addressing \u2013in an integrated fashion- the challenges at the level of the fetus, the mother and the fetomaternal barrier. At the core of this proposal lies an international registry of pregnant women with cancer, along with a registry of their children, and biobanks of maternal, placental, cord blood and tumoral tissues. Research track \u2018child\u2019 aims to deliver robust evidence of fetal safety. Research track \u2018mother\u2019 aims to address the emerging concerns in the oncological management of the mother, and specifically, the possible distinct biology of pregnancy-associated breast cancer, the most frequent cancer type in pregnancy. The research approach includes large-scale clinical follow-up studies along with laboratory studies on patient biomaterials, including pharmacological investigations and RNA-sequencing studies. Complementary to these studies is research track \u2018placenta\u2019 in which cutting-edge models of human placental research are used to address the poorly understood physiological basis of the placental barrier function in this specific situation. This ambitious program will rely on a multidisciplinary team of experts. Not only may the scientific deliverables of this proposal constitute a major step forward to the well-being of both mother and fetus in a pregnancy complicated by cancer, the methodological approach may also provide critical impetus to further research in this field.", "To": ["2020-09-30, ongoing project |"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2015-10-01"], "Project_ID": ["647047"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["UNIVERSITAT DE BARCELONA", "UNIVERSITAT DE BARCELONA", "THE UNIVERSITY OF SUSSEX"], "EU_Contribution": ["EUR 1 495 753"], "Project_Title": ["Women travelling to seek abortion care in Europe: the impact of barriers to legal abortion on women living in countries with ostensibly liberal abortion laws"], "Total_Cost": ["EUR 1 495 753"], "Country": ["Spain", "Spain", "United Kingdom"], "Project_ACR": ["BAR2LEGAB"], "Technology_Description": "In many European countries with ostensibly liberal abortion laws, women face legal restrictions to abortion beyond the first trimester of pregnancy, as well as other barriers to legal abortion, in particular shortages of providers willing and able to offer abortion due to poor training and to conscientious objection among physicians. The Council of Europe has recognized that conscientious objection can make access to safe abortion more difficult or impossible, particularly in rural areas and for low income women, who are forced to travel far to seek abortion care, including abroad. The WHO also highlights that delaying abortion care increases risks for women\u2019s reproductive health. Despite the relevance of this topic from a public health and human rights perspective, the impact of procedural and social barriers to legal abortion on women in countries with ostensibly liberal abortion laws has not been studied by social scientists in Europe. This five-year research project is envisaged as a ground-breaking multi-disciplinary, mixed-methods investigation that will fill this gap, by capitalizing on previous, pioneer anthropological research of the PI on abortion and conscientious objection. It will contribute to the anthropology of reproduction in Europe, and particularly to the existing literature on abortion, conscientious objection and the medicalization of reproduction, and to the international debate on gender inequalities and citizenship, by exploring how barriers to legal abortion are constructed and how women embody and challenge them in different countries, by travelling or seeking illegal abortion, as well as their conceptualizations of abortion and their self perception as moral/political subjects. The project will be carried out in France, Italy and Spain, where the few existing studies show that women face several barriers to legal abortion as well as in the UK, the Netherlands and Spain, where Italian and French women travel to seek abortion care.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["680004"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["DOKUZ EYLUL UNIVERSITESI"], "EU_Contribution": ["EUR 145 845,60"], "Project_Title": ["DEVELOPMENT OF A HIGH PERFORMANCE FLOWING ELECTROLYTE-DIRECT METHANOL FUEL CELL STACK THROUGH MODELING AND EXPERIMENTAL STUDIES"], "Total_Cost": ["EUR 145 845,60"], "Country": ["Turkey"], "Project_ACR": ["FEDMFC"], "Technology_Description": "Flowing electrolyte-direct methanol fuel cell (FE-DMFC) is a novel energy technology in which the performance of the conventional DMFC is increased by eliminating the methanol crossover problem. There are some studies found in the literature to predict the performance of this fuel cell using one and two-dimensional single phase models. The validation of these models was done using the experimental test results for the membrane electrode assemblies (MEA) built with conventional materials. In this project, the main objective is to develop a high performance FE-DMFC stack through modeling and experimental studies. For this purpose, a three-dimensional and two-phase multiphysics model, which includes all the transport phenomena in all the layers, will be developed to predict the performance of the FE-DMFC stack accurately. To validate this model, a FE-DMFC stack based on alternative MEA materials (i.e. materials having lower cost, and higher stability and reaction kinetics) will be manufactured in-house in cooperation with the partner organization in Europe. After validating this model, the effect of significant design and operating parameters of the stack on the output parameters will be investigated; thus the parameters that increase the performance of this fuel cell mostly will be determined. This project will have have a very positive impact in Dr. Colpan's career as it will help him to develop lasting integration with his institution and increase his network in Europe. The knowledge and results gained as a result of the research conducted during this project will be shared with other researchers, scientists, and general public through several activities (e.g. conference, seminar, and papers in the journals, webpage, and visiting schools). It is expected that the results of this project will make a significant progress toward commercialization of the FE-DMFC, which in turn contributes to the economy and social prosperity of European society.", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Turkey"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["661579"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE", "LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE"], "EU_Contribution": ["EUR 1 257 242,51"], "Project_Title": ["Research on Macroeconomic Fluctuations and Trade"], "Total_Cost": ["EUR 1 257 242,51"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["MACROTRADE"], "Technology_Description": "The proposal is divided into three strands whose main goals are to i) study macroeconomic fluctuations, ii) identify the mechanisms that drive and propagate these fluctuations, and iii) use the empirical findings to inform and formulate models that can be used for quantitative policy and positive analysis.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["681664"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["UNIVERSITAT DE VALENCIA", "UNIVERSITAT DE VALENCIA"], "EU_Contribution": ["EUR 1 716 954"], "Project_Title": ["Statistical Learning for Earth Observation Data Analysis."], "Total_Cost": ["EUR 1 716 954"], "Country": ["Spain", "Spain"], "Project_ACR": ["SEDAL"], "Technology_Description": "SEDAL is an interdisciplinary project that aims to develop novel statistical learning methods to analyze Earth Observation (EO) satellite data. In the last decade, machine learning models have helped to monitor land, oceans, and atmosphere through the analysis and estimation of climate and biophysical parameters. Current approaches, however, cannot deal efficiently with the particular characteristics of remote sensing data. In the coming few years, this problem will largely increase: several satellite missions, such as the operational EU Copernicus Sentinels, will be launched, and we will face the urgent need to process and understand huge amounts of complex, heterogeneous, multisource, and structured data to monitor the rapid changes already occurring in our Planet.", "To": ["2020-08-31, ongoing project |"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["647423"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["Fundaci\u00f3 Institut de Recerca Contra la Leucemia Josep Carreras", "Fundaci\u00f3 Institut de Recerca Contra la Leucemia Josep Carreras"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["GENOMIC, CELLULAR AND DEVELOPMENTAL RECONSTRUCTION OFINFANT MLL-AF4+ ACUTE LYMPHOBLASTIC LEUKEMIA"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Spain", "Spain"], "Project_ACR": ["INFANTLEUKEMIA"], "Technology_Description": "Infant cancer is very distinct to adult cancer and it is progressively seen as a developmental disease. An intriguing infant cancer is the t(4;11) acute lymphoblastic leukemia (ALL) characterized by the hallmark rearrangement MLL-AF4 (MA4), and associated with dismal prognosis. The 100% concordance in twins and its prenatal onset suggest an extremely rapid disease progression. Many key issues remain elusive: ", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2016-01-01"], "Project_ID": ["646903"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["UNIVERSITAT DE BARCELONA", "UNIVERSITAT DE BARCELONA"], "EU_Contribution": ["EUR 2 138 825"], "Project_Title": ["A New Strategy for Gravity and Black Holes"], "Total_Cost": ["EUR 2 138 825"], "Country": ["Spain", "Spain"], "Project_ACR": ["GravBHs"], "Technology_Description": "General Relativity (GR) encompasses a huge variety of physical phenomena, from the collision of astrophysical black holes, to the dynamics (via holography) of strongly-coupled plasmas and the spontaneous symmetry-breaking in superconductors. Black holes play a central role in all this. However, their equations are exceedingly hard to solve. The apparent lack of a generic tunable parameter that allows to solve the theory perturbatively (like the electric coupling constant in electrodynamics, or the rank of the gauge group in large-N Yang-Mills theory) is arguably the single most important obstacle for generic efficient approaches to the physics of strong gravity and black holes. I argue that one natural parameter suggests itself: GR can be defined in an arbitrary number of dimensions D. Recently I have demonstrated that the limit of large D is optimally tailored for the investigation of black holes, classical and potentially also quantum. Explicit preliminary studies have proved that the concept is sound, powerful, and applicable even in four dimensions.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["692951"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE", "LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE"], "EU_Contribution": ["EUR 1 662 942"], "Project_Title": ["Bayesian Peer Influence: Group Beliefs, Polarisation and Segregation"], "Total_Cost": ["EUR 1 662 942"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["BPI"], "Technology_Description": "The objective of this research agenda is to provide a new framework to model and analyze dynamics of group beliefs, in order to study phenomena such as group polarization, segregation and inter-group discrimination. We introduce a simple new heuristic, the Bayesian Peer Influence heuristic (BPI), which is based on rational foundations and captures how individuals are influenced by others' beliefs. We will explore the theoretical properties of this heuristic, and apply the model to analyze the implications of belief dynamics on social interactions. ", "To": ["2021-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-08-01"], "Project_ID": ["681579"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE", "LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE"], "EU_Contribution": ["EUR 1 294 699"], "Project_Title": ["Designing Effective Public Policies"], "Total_Cost": ["EUR 1 294 699"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["DEPP"], "Technology_Description": "This proposal outlines a number of projects in public economics, with links to other fields such as macro, real estate, labor, and gender economics. The projects evolve around several large administrative datasets from the UK and Denmark, and they advance approaches and methodologies that have recently been developed in public economics into new areas. There is a strong public policy focus running through the proposal, including tax policy, transfer policy, family policy, and indirectly monetary policy. The objective is to achieve a comprehensive understanding of how government interventions affect two key markets: the housing market and the labor market.", "To": ["2021-05-31, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["681696"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS", "STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["From haplotype to phenotype: a systems integration of allelic variation, chromatin state and 3D genome data"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["HAP-PHEN"], "Technology_Description": "High-throughput sequencing methods are breaching the barrier of $1000 per genome. This means that it will become feasible to sequence the genomes of many individual and create a deep catalog of the bulk of human genetic variation. A great task will lie in assigning function to all this genetic variation. Genome wide association studies have already shown that 40% of all loci significantly associated with disease are found in intergenic, supposedly regulatory regions. One of the current challenges in human genetics is that variants that affect expression on a single allele cannot be directly linked, because only have genotype information, rather then haplotype information. The overarching aim of the project is to resolve haplotypes in order to identify genetic variants that affect gene expression. We will do this in three sub-projects. In the first main project we will use 3D genome information gathered from Hi-C experiments to haplotype the genomes of six lymphoblastoid cell lines. We will integrate these data with chromatin profiling and RNAseq data in order to build integrative models for the prediction of gene expression and the effect of genetic variation on gene expression. In the second project we will perform haplotyping the breast cancer genes BRCA1/2 in a large cohort of individuals that come from families with a high-risk of hereditary breast cancer. Allelic imbalance in BRCA1/2 expression levels are known to be associated with an increased risk for breast cancer. We will aim to find genetic variants that are associated with a decreased allelic expression of BRCA1/2 to improve breast cancer risk assessment. Finally, we will develop a novel tool to study 3D genome organization of single alleles, which will allow us to identify how individual alleles are organized in the nucleus and identify multi-way interactions (i.e. involving more than two genomic loci). With this we hope to better understand how complex 3D organization contributes to gene regulation.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2015-09-01"], "Project_ID": ["637587"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE", "LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE"], "EU_Contribution": ["EUR 1 992 442,51"], "Project_Title": ["Narrative Ordering and Explanation in the Sciences: Historical Investigations and Perspectives"], "Total_Cost": ["EUR 1 992 442,51"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["NARRATIVENSCIENCE"], "Technology_Description": "The aim of this project is to understand the role of narrative in modern science. Narratives have appeared in many places in the human, social and natural sciences over the past two centuries. They can be found both in accounts of real situations and in simulations of virtual situations, in empirical work and in theorizing. It is clear that narratives have played important roles for scientists well beyond the simple act of reporting. Yet we lack an account of what kinds of thing scientists know from using narrative and how such \u2018narrative knowing\u2019 is constituted. Indeed, with the notable exceptions of medicine and evolutionary biology, even the study of those field narratives, as narratives, has been largely ignored by both historians of science and narrative scholars.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["694732"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK", "UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK"], "EU_Contribution": ["EUR 990 087"], "Project_Title": ["Creative Agency and Religious Minorities: \u2018hidden galleries\u2019 in the secret police archives in 20th Century Central and Eastern Europe"], "Total_Cost": ["EUR 990 087"], "Country": ["Ireland", "Ireland"], "Project_ACR": ["Hidden Galleries"], "Technology_Description": "This project concerns the creative agency of religious minorities in the transformation of Central and Eastern Europe societies in the 20th century. It constitutes the first comparative research on the secret police archives in the region from the perspective of the history and anthropology of religion and offers a radical perspectival shift on the value and uses of the secret police archives away from questions of justice and truth to questions of creative agency and cultural patrimony. Interdisciplinary in nature it combines archival, anthropological and cultural studies approaches to provide a re-examination and re-contextualization of the holdings of secret police archives in three states; Romania, Moldova and Hungary. The secret police archives, in addition to containing millions of files on individuals monitored by the state, also constitute a hidden repository of confiscated religious art and publications of religious minorities that were persecuted in the 20th century under fascism and communism. The investigation of these materials will be complemented by ethnographic research and the impact of the research will be extended through a public exhibition of previously hidden materials. The project has three principal stages: 1) copy/retrieve and catalogue examples of this creative material from the archives; 2) engage in ethnographic research with the communities that produced this material in order to explore the meaning and power of these artistic creations at the time of their production and in the context of post-socialism; 3) curate and stage a touring exhibition that re-presents the narratives and experiences of religious groups through their own artistic creations in order to conduct research in real time on questions of religious pluralism and intolerance in contemporary society. Through these three steps, this project will shed fresh light on the role that minority religious groups played in challenging the hegemonic order and in extending pluralism.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["677355"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["UNIVERSITAT DE BARCELONA", "UNIVERSITAT DE BARCELONA", "CONSIGLIO NAZIONALE DELLE RICERCHE"], "EU_Contribution": ["EUR 2 400 000"], "Project_Title": ["Testing the role of Mediterranean thermohaline circulation as a sensor of transient climate events and shaker of North Atlantic Circulation"], "Total_Cost": ["EUR 2 400 000"], "Country": ["Spain", "Spain", "Italy"], "Project_ACR": ["TIMED"], "Technology_Description": "The Mediterranean Sea is an excellent sensor of transient climate conditions at different time scales. Changes in Mediterranean water properties result from complex interactions between the Atlantic inflow, local climate and north and south atmospheric teleconnections. In turn, Mediterranean outflow waters spill into the Atlantic Ocean, thus acting as a net salt and heat source for the Atlantic Meridional Overturning Circulation (AMOC). Climate models anticipate changes in these circulation systems within decades; thus it becomes critical to understand the natural range of variations in the Mediterranean Thermohaline Circulation (MedTHC) and whether these can alter the AMOC. An innovative approach, based on both well-established and newly-developed analytical methods will be applied to characterize, qualitatively and quantitatively, past changes in the MedTHC dynamics. Specific time windows representing very different transient periods (18-14 ka BP; 9.5-6.5 ka BP and the last 2 kyr) will be targeted in order to understand the distinctive role that individual forcing mechanisms exerted in controlling MedTHC changes. Particular emphasis will be placed on building robust regional chronologies and proxy records with unprecedented high-resolution. This approach will combine proxy data from sediment cores and deep-sea corals along the main paths of water masses as they cross the Mediterranean basins and exit into the North Atlantic. This paleo-data analysis will be complemented with novel climate model paleo-simulations to test the sensitivity of the AMOC to changes in Mediterranean outflow under varying AMOC conditions. The main goals are to identify: (1) the natural range of MedTHC variability; (2) the forcings and inter-regional teleconnections driving MedTHC changes; (3) the associated impact onto the AMOC. The assessment of the forcings controlling MedTHC and the ensuing impact on the AMOC will allow us to gauge the consequences of future Mediterranean changes.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2017-01-01"], "Project_ID": ["683237"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["UNIVERSITAT DE BARCELONA", "UNIVERSITAT DE BARCELONA", "INSTITUTE OF POLITICAL ECONOMY AND GOVERNANCE"], "EU_Contribution": ["EUR 2 500 000"], "Project_Title": ["The Birth of Party Democracy. The Emergence of Mass Parties and the Choice of Electoral Laws in Europe and North America (1870-1940)"], "Total_Cost": ["EUR 2 500 000"], "Country": ["Spain", "Spain", "Spain"], "Project_ACR": ["partydemocracy"], "Technology_Description": "The project will develop a theoretically-based account of the emergence of mass parties, the choice of electoral institutions, and the final crystallization of different party systems in Europe and North America during the emergence of mass democracy and the formation of modern parties (1870-1940). It will combine statistical and historical methods to explain the formation of diverse party systems as the outcome of political choices made at particular critical junctures that involved the creation of nonsocialist and socialist parties, the mobilization of their corresponding electorates, and the strategic response of ppolitical elites (often through the manipulation of electoral laws and sometimes through the creation of new electoral coalitions).", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2017-01-01"], "Project_ID": ["694318"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE", "LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE"], "EU_Contribution": ["EUR 1 049 855"], "Project_Title": ["Labour market dynamics and optimal policies"], "Total_Cost": ["EUR 1 049 855"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["DYNAMICSS"], "Technology_Description": "From pension reforms to UI extensions, the optimal tax and program design literature is often ill-equipped to provide clear guidance in policy debates on the reform of social insurance and tax-and-benefit systems. The reason is that this literature is mostly focused on static settings, while these programs are inherently dynamic: they specify a schedule of tax and benefits that is time or state dependent and they affect individuals\u2019 decisions throughout their lifetime. ", "To": ["2021-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["679704"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["MARTIN-LUTHER-UNIVERSITAET HALLE-WITTENBERG"], "EU_Contribution": ["EUR 236 210,40"], "Project_Title": ["The Dynamics of Solidarity on Madagascar: An Ethnography of Political Conflicts and Appeasement Strategies in the Context of a Pronounced Consens Norm"], "Total_Cost": ["EUR 236 210,40"], "Country": ["Germany"], "Project_ACR": ["DySoMa"], "Technology_Description": "The aim of this anthropological research project is to improve understanding of the peace-making processes operating in the ongoing Malagasy political crisis. A dispute in 2009 over the Malagasy presidency, the most powerful political position on the island, marked the beginning of a particularly difficult period. At first tensions were limited to the national political level, but the situation rapidly degenerated into a more general social crisis as international support was suspended, the economy plummeted down and the population of about 22 million had to cope with great insecurity.", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-11-01"], "Project_ID": ["702497"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIWERSYTET MARII CURIE-SKLODOWSKIEJ"], "EU_Contribution": ["EUR 245 361,60"], "Project_Title": ["Effect of water and wastewater treatment on the properties of engineered nanomaterials (ENMs) in context of their fate, toxicity and interaction with other contaminants"], "Total_Cost": ["EUR 245 361,60"], "Country": ["Poland"], "Project_ACR": ["SAFEnano"], "Technology_Description": "The primary goal of this study is to use the state-of-the-art methods to study the changes of engineered nanomaterials (ENMs) during water and wastewater treatment and to evaluate how these changes will affect ENMs fate, toxicity and interaction with other contaminants. ", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Poland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["699794"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["FUNDACIO INSTITUT DE RECERCA DE L'ENERGIA DE CATALUNYA", "UNIVERSITAT POLITECNICA DE CATALUNYA", "TECHNISCHE UNIVERSITEIT DELFT", "VLAAMSE INSTELLING VOOR TECHNOLOGISCH ONDERZOEK N.V.", "ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA", "UNIVERSITE JOSEPH FOURIER GRENOBLE 1", "UNIVERSITE GRENOBLE ALPES", "GENERAL ELECTRIC DEUTSCHLAND HOLDING GMBH", "EFACEC ENERGIA - MAQUINAS E EQUIPAMENTOS ELECTRICOS SA"], "EU_Contribution": ["EUR 3 527 433"], "Project_Title": ["Innovative controls for renewable sources Integration into smart energy systems"], "Total_Cost": ["EUR 3 527 433"], "Country": ["Spain", "Spain", "Netherlands", "Belgium", "Italy", "France", "France", "Germany", "Portugal"], "Project_ACR": ["INCITE"], "Technology_Description": "The continuous increase of the share of renewable energy sources is redefining the electrical networks. In future infrastructures, an important number of agents (sources, storage devices and consumers) will have intelligent interfaces allowing the regulation of the injection and extraction of power into the grid. This context will create multiple alternatives to increase the efficiency in electricity generation and consumption, to reduce energy costs and to provide a more reliable operation of electrical grids. These future networks will be only possible with suitable control algorithms. INCITE is a multi-sectoral consortium gathering experts on control and power systems, from academia and industry with the purpose of providing innovative control solutions for the future electrical networks.", "To": ["2019-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-12-01"], "Project_ID": ["675318"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "JOHANNES GUTENBERG-UNIVERSITAT MAINZ", "UNIVERSITAT DE BARCELONA", "UNILEVER RESEARCH AND DEVELOPMENT VLAARDINGEN BV", "CORDOUAN TECHNOLOGIES SAS", "UNIVERSITAT WIEN", "FORSCHUNGSZENTRUM JULICH GMBH", "FREIE UNIVERSITAET BERLIN", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 3 899 357,64"], "Project_Title": ["TRANSPORT OF SOFT MATTER AT THE NANOSCALE"], "Total_Cost": ["EUR 3 899 357,64"], "Country": ["United Kingdom", "France", "Germany", "Spain", "Netherlands", "France", "Austria", "Germany", "Germany", "United Kingdom"], "Project_ACR": ["NANOTRANS"], "Technology_Description": "We propose a Multi-Partner ITN-ETN network on Transport of Soft Matter at the Nanoscale. The scientific topic, which is the focus of the proposal, is an emerging field of science and technology. Challenges such as design of environmentally friendly engineering materials or understanding the principles of biological organization crucially depend on fundamental understanding of transport of fluids and colloids at the nanoscale. Topics we will study within NANOTRANS are at the core of modern technology (i.e. active design of \u201csmart\u201d nanomaterials, nanofluidic and \u201clab on a chip\u201d devices, sustainable nanocompounds, energy storage, contaminants dissemination in environment, oil recovery, drug delivery and disease treatment). ", "To": ["2020-02-29, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["674979"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["FUNDACIO INSTITUT DE RECERCA DE L'ENERGIA DE CATALUNYA", "FUNDACIO INSTITUT DE RECERCA DE L'ENERGIA DE CATALUNYA"], "EU_Contribution": ["EUR 1 841 387"], "Project_Title": ["Breaking the temperature limits of Solid Oxide Fuel Cells: Towards a newfamily of ultra-thin portable power sources"], "Total_Cost": ["EUR 1 841 387"], "Country": ["Spain", "Spain"], "Project_ACR": ["ULTRA-SOFC"], "Technology_Description": "Solid Oxide Fuel Cells (SOFCs) are one of the most efficient and fuel flexible power generators. However, a great limitation on their applicability arises from temperature restrictions. Operation approaching room temperature (RT) is forbidden by the limited performance of known electrolytes and cathodes while typical high temperatures (HT) avoid their implementation in portable applications where quick start ups with low energy consumption are required. ", "To": ["2021-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2016-04-01"], "Project_ID": ["681146"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["STICHTING VU", "UNIVERSITY OF YORK", "MAGYAR TUDOMANYOS AKADEMIA TERMESZETTUDOMANYI KUTATOKOZPONT", "UNIVERSITAT DE BARCELONA", "VERNALIS (R&D) LIMITED", "ZOBIO BV", "BEACTICA AB", "Novartis Pharma AG"], "EU_Contribution": ["EUR 3 842 481,96"], "Project_Title": ["FRAGments training NETwork"], "Total_Cost": ["EUR 3 842 481,96"], "Country": ["Netherlands", "United Kingdom", "Hungary", "Spain", "United Kingdom", "Netherlands", "Sweden", "Switzerland"], "Project_ACR": ["FRAGNET"], "Technology_Description": "The promise of more efficient lead discovery is fuelling the enthusiasm for fragment-based lead discovery (FBLD). In this approach, highly sensitive biochemical and biophysical screening technologies are being used to detect the low affinity binding of low molecular weight compounds (the so-called fragments) to protein targets that are involved in pathophysiological processes. By investigating the molecular interactions between fragment hit(s) and the target protein, a detailed understanding of the binding event is obtained. This enables the rational and efficient optimisation of the hit fragment. The optimised compounds represent high quality leads for drug development. The necessary FBLD technologies and approaches have emerged mainly from small and specialised biotech companies. At present, FBLD is being adopted throughout pharmaceutical sciences, including by pharmaceutical companies, SMEs and academic research groups. So far, the necessary training that is needed to obtain an holistic view of the possibilities and opportunities that FBLD provides is missing, most likely because the highly multidisciplinary nature of the FBLD work is difficult to capture within one (academic) institute. Therefore, we have established FragNet as a dedicated FBLD training network. The consortium consists of the most prominent pharmaceutical companies, biotech companies and academic groups that have jointly shaped the FBLD research area. FragNet is committed to train 15 ESRs in all facets of FBLD using the combined technologies, skills and knowledge. This will include both research (e.g., technologies on the interface of chemistry and biology) and transferable skill sets (e.g., writing, media training, entrepreneurship and thorough understanding of scientific knowledge transfer). This will enable the ESRs to excel in today\u2019s drug discovery and chemical biology programmes that are performed in public and private organisations in the pharmaceutical sciences.", "To": ["2020-02-29, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-03-01"], "Project_ID": ["675899"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["UNIVERSITAT DE BARCELONA"], "EU_Contribution": ["EUR 242 683,20"], "Project_Title": ["Using the halo model to maximise the information gain from forthcoming weak-lensing surveys."], "Total_Cost": ["EUR 242 683,20"], "Country": ["Spain"], "Project_ACR": ["Halo modelling"], "Technology_Description": "The mechanism behind the current phase of accelerated expansion of the Universe is not understood. Either space is filled with dark energy, a substance that has never been detected in an earth-bound laboratory, or the gravitational equations of Einstein are incorrect and acceleration arises naturally within the correct theory. There are now a wide variety of models that purport to explain accelerated expansion, and often these models make different predictions for how matter is clustered in the Universe. Weak gravitational lensing uses measurements of the deflection of light from distant galaxies to infer the intervening distribution of matter, and thus allows us to discriminate between acceleration models. However, in its present state the lack of accurate modelling for the distribution of matter as a function of cosmological paradigm will be the major limitation in the interpretation of forthcoming weak lensing data: the goal of the 'halo modelling' project is to provide the required accuracy of modelling. To achieve this, the Fellow will take a novel hybrid approach; combining results from perturbation theory, high-accuracy simulations and semi-analytics. Crucially, the 'halo modelling' project will simultaneously improve our understanding of the distribution of baryons relative to dark matter in the Universe, and incorporate this. The current ignorance of the level of mass redistribution caused by baryonic feedback processes has the potential to severely degrade the constraining power of forthcoming lensing surveys.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["702971"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE", "LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE"], "EU_Contribution": ["EUR 1 287 755"], "Project_Title": ["Market Beliefs and Optimal Policy in the Presence of Disasters"], "Total_Cost": ["EUR 1 287 755"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["Disasters"], "Technology_Description": "My proposal consists of two strands linked by a common theme--namely a concern for the impact of disasters, in financial markets and more generally--and by a shared methodology.", "To": ["2020-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-05-01"], "Project_ID": ["639744"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN", "Fundaci\u00f3 Institut de Recerca Contra la Leucemia Josep Carreras", "KAROLINSKA INSTITUTET", "UNIVERSITAT ROVIRA I VIRGILI", "INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH", "BIOBAM BIOINFORMATICS SL", "CHRONOS THERAPEUTICS LIMITED", "4SC DISCOVERY GMBH", "NESTLE INSTITUTE OF HEALTH SCIENCES SA"], "EU_Contribution": ["EUR 3 825 128,16"], "Project_Title": ["Chromatin and MetabolismChromatin-metabolism interactions as targets for healthy living"], "Total_Cost": ["EUR 3 825 128,16"], "Country": ["Germany", "Spain", "Sweden", "Spain", "France", "Germany", "United Kingdom", "Germany", "Spain", "United Kingdom", "Germany", "Switzerland"], "Project_ACR": ["ChroMe"], "Technology_Description": "Metabolic disorders are at pandemic levels. Based on recent estimates, ~50% of Europeans are overweight, 20% are obese and 10% have type II diabetes. Obesity and insulin resistance impact European health to the tune of \u20ac110 billion per year. These disorders have genetic, nutritional and lifestyle causes. However, the molecular mechanisms that link nutrients and lifestyle to gene activity and chromatin are poorly understood, and drug targets are only starting to be identified. Pioneering experiments by ChroMe labs now reveal how sugars, exercise, the gut microbiome and novel drugs regulate chromatin. These novel links promise to substantially improve our understanding and treatment of metabolic disorders. National governments and the EU invest major resources to address the burden of the \u201cmetabolic syndrome\u201d. However, there is an urgent need for expert human capital able to dissect metabolic diseases, exploit new targets and establish innovative therapies. No local nor international program currently provides adequate training at this emerging interface of chromatin and metabolism. ", "To": ["2020-02-29, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-03-01"], "Project_ID": ["675610"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE", "LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE"], "EU_Contribution": ["EUR 1 568 276"], "Project_Title": ["New perspectives on inflation"], "Total_Cost": ["EUR 1 568 276"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["INFL"], "Technology_Description": "The research in this proposal will contribute to our knowledge of the dynamics and effects of inflation through the perspective of risk-adjusted inflation and valuation formulas. The goal is to provide new perspectives on inflation and its impact on resource constraints.", "To": ["2021-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-07-01"], "Project_ID": ["682288"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY", "UNIVERSITAET BAYREUTH", "HUMBOLDT-UNIVERSITAET ZU BERLIN", "TECHNISCHE UNIVERSITEIT EINDHOVEN", "NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO", "INNOVATIONLAB GMBH", "UNIVERSITE DE FRIBOURG", "UNIVERSITY OF CYPRUS", "UNIVERSITAT DE VALENCIA"], "EU_Contribution": ["EUR 3 870 919,80"], "Project_Title": ["Interfaces in opto-electronic thin film multilayer devices"], "Total_Cost": ["EUR 3 870 919,80"], "Country": ["United Kingdom", "United Kingdom", "Israel", "Germany", "Germany", "Netherlands", "Netherlands", "Germany", "Switzerland", "Cyprus", "Spain"], "Project_ACR": ["INFORM"], "Technology_Description": "Development of new materials over the past decade paved the way for organic/hybrid electronics into commercial applications. Now, perfection of material interfaces in organic/hybrid thin-film devices is key to drive the technology further and enable new, more advanced applications. INFORM offers a paradigm shift from focusing on materials to focusing on devices by probing, modelling and controlling relevant processes that take place at interfaces, e.g. charge transfer, injection and collection. By training researchers in this exciting, highly multidisciplinary area, INFORM contributes to the need for skilled, knowledgeable researchers in the field of multilayer thin-film devices in Europe. INFORM will generate fundamental insights and apply them to improve the performance and reliability of relevant devices that will allow INFORM\u2019s industrial partners to grow their markets and take full advantage of the low-temperature, low-cost and large-area processing potential of new generation semiconductors. The challenges are wide-ranging and thus require a cross-European, multidisciplinary, intersectorial and multifaceted approach. The INFORM network consists of partners with complementary skills and toolboxes, including 9 academic groups fully equipped, experienced and knowledgeable in multilayer device research and supervision. The involvement of 4 non-academic partners at the highest level, through supervision of 2 ESRs and secondments, ensures ESR exposure to the industrial workplace and simultaneously provides benefits to the non-academic partners. Complementary training activities in personal skills (e.g writing and communicating), is given by a specialist partner. The combination of high level research and intense training endows the ESRs with multidisciplinary know-how and hands-on skills for careers that impact not only the field of multilayer devices, but also the broader quests for renewable energy resources and development of nanotechnology.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["675867"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS", "STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS"], "EU_Contribution": ["EUR 2 497 125"], "Project_Title": ["Genomics of Chromosome Architecture and Dynamics in Single Cells"], "Total_Cost": ["EUR 2 497 125"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["GoCADiSC"], "Technology_Description": "The spatial architecture of mammalian interphase chromosomes, each consisting of tens of megabases of DNA, poses an intriguing topological problem and is relevant for various nuclear functions. A major challenge is that chromosome architecture exhibits substantial stochastic cell-to-cell variation. To unravel the principles of chromosome organization, new single-cell genome-wide approaches that capture the intrinsic variability are needed.", "To": ["2022-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-03-01"], "Project_ID": ["694466"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["UNIVERSITY OF DURHAM", "UNIVERSITY OF DURHAM", "LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE", "UNIVERSITA CA' FOSCARI VENEZIA"], "EU_Contribution": ["EUR 2 092 125"], "Project_Title": ["Knowledge For Use [K4U]: Making the Most of Social Science to Build Better Policies"], "Total_Cost": ["EUR 2 092 125"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom", "Italy"], "Project_ACR": ["K4U"], "Technology_Description": "\u2018Research is an investment in our future\u2019 says Horizon 2020. That\u2019s only true if you know what to do with it. When it comes to social policy, we don\u2019t really know how to put our research results to use. K4U aims to remedy this. K4U will construct a radically new picture of how to use social science to build better social policies. This picture will be founded on an ambitious philosophical study of the technology of social science including a thorough reconceptualisation of objectivity, deliberation and the role of values in the science/society interface. Current work, primarily by the evidence-based policy and practice movement, focusses on knowledge production: encouraging high quality studies and vetting them. Little attention goes to knowledge use: How is social science knowledge to be used in policy design and deliberation \u2013 how should it be used so that policy outcomes are more effective and more reliably predictable and competing values and points of view are respected in policy choice and implementation? ", "To": ["2020-10-31, ongoing project |"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-11-01"], "Project_ID": ["667526"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["UNIVERSITAT DE VALENCIA"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Long Range Surface Plasmon Polaritons as an Alternative Information Carrier for Nanoscale Quantum Circuitry"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["QuP"], "Technology_Description": "The aim of this innovative and high-impact interdisciplinary proposal is to investigate the potential properties and applications of plasmonic metallic nanostructures that enable the confinement of light to scales beyond the diffraction limit, known as quantum plasmonics. Latest studies have revealed the quantization of surface plasmon polaritons (SPPs). It could be the stepping stone for the generation of miniaturized photonic components for the quantum control of light. This implies that the SPPs would represent a totally new sort of information carrier for nanoscale circuitry, enabling a revolutionary bridge between current diffraction-limited microphotonics and bandwith-limited nanoelectronics, paving the way for integrated quantum information processing. Thus, in a first stage we will develop integrated nanoscale quantum plasmonics building blocks on-a-chip, such as efficient single-photon sources or transistors, which is the component required for the fabrication of true nanoscale quantum computing logic gates. We also plan to exploit the low-Ohmic-losses and prospects for large scale production of ultra-compact cutting-edge graphene plasmonic circuits. This research will be lastly applied to single molecule sensing. Experiments will be performed using innovative techniques for nanofabrication of photonic nanostructures and for characterization. The expected results will allow taking advantage of quantum interference effects, setting up the optical response of the extremely low losses Long Range (LR) SPPs modes within a quantum framework and showing that graphene layers produce strong light-matter interaction and extreme optical field confinement. The results will be compared with ab initio simulations, giving a precise and consistent experimental and theoretical panorama of quantum plasmonics.", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["704998"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["WELSH ASSEMBLY GOVERNMENT"], "EU_Contribution": ["EUR 9 558 000"], "Project_Title": ["Strengthening International Research Capacity in Wales"], "Total_Cost": ["EUR 19 116 000"], "Country": ["United Kingdom"], "Project_ACR": ["SIRCIW"], "Technology_Description": "Scientists in Wales are efficient, productive, collaborative, impactful and in many cases world leading. Recent evidence shows scientific excellence but a lack of critical mass in areas most likely to drive a knowledge economy through innovation and translation. This application forms the foundation of the 'S\u00ear Cymru (Stars Wales) II Programme' designed to produce a step change in Welsh scientific capacity, building on excellence and investing in early career researchers. This integrated proposal marries Marie Sk\u0142odowska-Curie COFUND fellowships with European Structural Funds, university, industrial and Welsh Government funding to bring in 140 new fellowships (90 via SIRCIW) in strategic areas including clinical science, engineering, physics, mathematics and applied Social Sciences.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2014-FP - Marie Sk\u0142odowska-Curie Co-funding of regional, national and international programmes (COFUND-FP)"], "Funding_scheme": ["MSCA-COFUND-FP - Fellowship programmes"], "Coordinated_in": ["United Kingdom"], "Activity": ["Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2015-09-01"], "Project_ID": ["663830"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2014"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSITY OF LEEDS", "CONSIGLIO NAZIONALE DELLE RICERCHE", "UNIVERSITE PARIS-SUD", "UNIVERSITAET REGENSBURG"], "EU_Contribution": ["EUR 2 798 445"], "Project_Title": ["Ultrashort Pulse Generation from Terahertz Quantum Cascade Lasers"], "Total_Cost": ["EUR 2 798 445"], "Country": ["France", "United Kingdom", "Italy", "France", "Germany"], "Project_ACR": ["ULTRAQCL"], "Technology_Description": "The generation of ultrafast and intense light pulses is an underpinning technology across the electromagnetic spectrum enabling the study of fundamental light-matter interactions, as well as industrial exploitation in a plethora of applications across the physical, chemical and biological sciences. A benchmark system for such studies is the modelocked Ti:Sapphire laser, which has grown from being a laboratory curiosity to an essential tool in a broad range of application sectors. Beyond Ti:Sapphire systems, there have been impressive developments in semiconductor based devices for pulse generation in the optical range. These benefit from low system costs and are an enabling technology in new application domains including high speed communications.", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-1-2014 - FET-Open research projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["665158"], "Call_for_Proposal": ["H2020-FETOPEN-2014-2015-RIA"]}, -{"Partners": ["LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE", "LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE"], "EU_Contribution": ["EUR 1 217 313,76"], "Project_Title": ["INDIVIDUAL ACTION THROUGH SOCIAL ORGANIZATIONS: THE CASE OF POVERTY"], "Total_Cost": ["EUR 1 217 313,76"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["IATSO"], "Technology_Description": "There is arguably a lack of research on organizations with social goals in management. For an extreme case, i.e., of poverty, Prahalad (2006) described compelling examples of innovative organizations in South Asia, which he suggested served the poor. However, very little is known about: 1) What factors \u2018cause\u2019 social organizations, for instance, in settings of extreme poverty, to grow and scale up \u2018successfully,\u2019 and how and why?, and 2) What organizational factors influence \u2018social performance\u2019 for target groups, and how and why, and under which conditions (where and when), and for whom? Building on insights from our earlier theoretical and empirical work on networks, leadership, and learning, as well as our extensive pilot studies in India, we will explore how and why social organizations grow and scale up, in relation to social outcomes for relevant target groups, using mixed methods (a qualitative phase followed by a quantitative phase, to first build and then test theory). We propose to study organizations in an extreme setting, where arguably, social problems are worst: of poverty in South Asia, and picked the education sector given its potential importance for enabling people to move out of poverty. We believe that a better understanding of how and why organizations scale up successfully to enable target groups in poverty to be more proactive is also relevant from a practical perspective. It is for instance at the heart of the new Sustainable Development Goals, and it is our hope to make a contribution into this direction.", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-11-01"], "Project_ID": ["695524"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA", "UNIVERSITE PARIS-SUD", "UNIVERSITAT DE BARCELONA", "ALACRIS THERANOSTICS GMBH", "AB ANALITICA SRL"], "EU_Contribution": ["EUR 2 906 801,25"], "Project_Title": ["PROtein SEQuencing using Optical single molecule real-time detection"], "Total_Cost": ["EUR 2 906 801,25"], "Country": ["Italy", "France", "Spain", "Germany", "Italy"], "Project_ACR": ["PROSEQO"], "Technology_Description": "The advent of analytical techniques with extremely low limits of detection has led to dramatic progresses mostly in the field of nucleic acids sequencing. Despite the advent of the next generation sequencing platforms, the current genome sequencing task remains formidable, and revolutionary advances in DNA sequencing technology are still demanded. Nevertheless, the primary actors in virtually all life processes are the proteins coded by DNA sequences known as genes. Proteins can yield far more compelling revelations than may be gleaned from DNA alone. Protein sequencing may radically transform patient treatment, enabling precise monitoring of disease response to therapeutics at the molecular level. Single-molecule sequencing of proteins is of enormous value, offering the potential to detect diminishingly small quantities of proteins that may have been altered by alternative splicing or post-translational modification. In this project, we build upon current state-of-the-art sequencing technologies to develop novel proof-of-principle technologies for high-throughput protein sequencing and single molecule DNA/RNA sequencing. The work proposed herein will provide: (i) a new sequencing technology development that utilizes plasmonic nanostructures in order to enhance the optical detection and to control the molecules movement by means of optical trapping; (ii) a novel approach of plasmonic based optical spectroscopy for sequencing of protein; (iii), a rigorous analytical model to reconstruct the exact sequence from the signals recorded; and (iv) a plasmonic device that can perform both nucleic acids and amino-acids sequencing in one functional unit. These research efforts provide a foundation for the novel use of systems for a wide range of applications, such as the framework to investigate next generation protein sequencing, as well as high-throughput DNA sequencing and genetic diagnostics.", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-1-2014 - FET-Open research projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Chiara Andreoli", "Tel.: +3901071781854", "Fax: +39 010 7170817", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-03-01"], "Project_ID": ["687089"], "Call_for_Proposal": ["H2020-FETOPEN-2014-2015-RIA"]}, -{"Partners": ["THE UNIVERSITY OF EXETER", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "PLATFORM KINETICS LIMITED", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "UNIVERSITAT DE BARCELONA"], "EU_Contribution": ["EUR 2 978 882,50"], "Project_Title": ["Magnetically actuated bio-inspired metamaterials"], "Total_Cost": ["EUR 2 978 882,69"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom", "France", "Spain"], "Project_ACR": ["ABIOMATER"], "Technology_Description": "This project will deliver a new class of metamaterials whose functionality can be controlled by external magnetic fields. The materials consist of micromotors, comprising an anisotropically \u201chard\u201d and \u201csoft\u201d ferromagnetic particle pair embedded in a polymer matrix, and promise wide-ranging technological applications. The project, involves 5 partners with expertise in experimental and theoretical physics, biological science and technology. Building upon a detailed analysis of the physical properties of the individual motors, and their dependency on their magnetic and material properties, the team will develop methods for incorporating the motors into elastic membranes (MEMs). We shall analyse the mechanical and optical properties of these constructs and the ways in which they can be modulated by the external magnetic fields. These novel properties will then be used to produce prototype devices: ", "To": ["2018-10-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-1-2014 - FET-Open research projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2015-11-01"], "Project_ID": ["665440"], "Call_for_Proposal": ["H2020-FETOPEN-2014-2015-RIA"]}, -{"Partners": ["LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Identity Management on Social Media by Diasporic LGBTQs"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["FACELOOK"], "Technology_Description": "The internet, and social media in particular, create new opportunities and pose new challenges for the ways people think about themselves as well as manage the expressions of their identities. In this research project I aim to enrich our knowledge about the transformations of identity in the new media landscape of the early XXI century by investigating those transformations from the perspective of diasporic LGBTQs, that is, lesbian, gay, bisexual, transgender and queer people. I will focus on the latest theories on social media and identity about 1) fixating the fragmented self (van Zoonen 2013), 2) collapsed contexts (boyd 2011) and 3) the multiplication of contexts (Papacharissi 2011), by investigating those phenomena from the perspective of Polish post-accession immigrants to the UK. I will examine what diasporic LGBTQs and their social media\u2019s uses can teach us about the relationship between the internet and identity, as well as what opportunities and difficulties social media create to a group that faces different challenges of exclusion and discrimination. I will first use a quantitative survey to map the diversity of social media used by Polish LGBTQs in the UK. However, because I am primarily interested in meanings of daily media practices, it is qualitative methods, and in-depth interviews in particular, which will form the core of my methodological toolkit. At the same time, to trigger more and better quality data I will combine traditional qualitative methods with such innovative approaches as think-aloud protocols (which require from participants to talk about the activity in which they are involved) and digital methods (the methods of the medium under scrutiny).", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["699745"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE", "LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE"], "EU_Contribution": ["EUR 1 275 043,75"], "Project_Title": ["Information Technology and Institutions Supporting Human Capital Accumulation and Exchange"], "Total_Cost": ["EUR 1 275 043,75"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["INFO TECHNOLOGY"], "Technology_Description": "Information technology revolutions transform the production and exchange of ideas and drive profound institutional and cultural change. History provides unique settings to document the causal impact of changes in information technology and institutions, and the best evidence on their long-run effects.", "To": ["2020-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-05-01"], "Project_ID": ["638957"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS", "STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS"], "EU_Contribution": ["EUR 149 500"], "Project_Title": ["Exploiting vulnerabilities in protein synthesis for cancer diagnosis and therapy"], "Total_Cost": ["EUR 149 500"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["Diricore"], "Technology_Description": "Tumor growth requires continuous synthesis of proteins, nucleic acids and lipids that are important components of the cell. Demand for amino acids as the building blocks for protein synthesis in rapidly dividing tumor cells is often much higher than that of normal cells. Such increased demand can represent a vulnerability of the tumor. Importantly, this vulnerability is already being exploited for therapy in one instance: Addition of L-asparginase - an enzyme lowering the concentration of the amino acid asparagine in blood - to chemotherapy against acute lymphoblastic leukemia, resulted in a dramatic increase in cure from 5% to 95% of patients treated. Recent scientific publications highlight the fact that tumors are often metabolically rewired, and multiple examples of altered amino acid demand and/or turnover have been demonstrated in different cancer indications. Multiple drugs are under development that target amino acid availability, uptake or biosynthesis.", "To": ["2016-10-31, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2014 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2015-05-01"], "Project_ID": ["665317"], "Call_for_Proposal": ["ERC-2014-PoC"]}, -{"Partners": ["STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["Breaking down arenavirus cell entry"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["BRACE"], "Technology_Description": "Hemorrhagic fever viruses are serious human threats for which we don\u2019t have adequate treatments available, which is painfully highlighted by the current Ebola virus outbreak in Western Africa. These viruses are obligatory intracellular parasites that make use of the host machinery at every phase of their infection cycle. Virus attachment and entry are the initial steps, which requires engagement of a viral glycoprotein with a cell surface receptor. This interaction then triggers internalization of the virus particle via a Trojan horse-like vesicular pathway, eventually resulting in the release of the viral genome into the cytoplasm of the target cell. We have recently shown that cell entry of at least some hemorrhagic fever viruses (i.e. Ebola virus and Lassa virus) is even more sophisticated, as it requires triggered-recognition of an intracellular receptor as an unexpected additional step. A precise understanding of how these major pathogens enter cells is required to reveal the mechanisms by which they cause disease. In this application, I will combine targeted engineering of viral systems with a genomics approach that enables crystal-clear, yeast-like genetics in human cells. Focusing on arenaviruses, these genome-wide surveys will reveal host factors indicative of virus entry tactics never observed before. I will use biochemistry, microscopy, and cell biological assays to examine in detail the virus-host interplay with these factors and will identify promising new antiviral targets for arenavirus family members that cause human disease. Overall, I foresee that this project will provide a much-needed window on the unique cell entry strategies of these lethal pathogens, which thus far revealed a surprising diversity in the biological host networks being hijacked to establish infection.", "To": ["2017-09-30, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Netherlands"], "Activity": ["Research Organisations"], "From": ["2015-10-01"], "Project_ID": ["660417"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK"], "EU_Contribution": ["EUR 175 866"], "Project_Title": ["Stilbene and entomopathogenic nematodes: Unlocking the potential"], "Total_Cost": ["EUR 175 866"], "Country": ["Ireland"], "Project_ACR": ["STEPN-UP"], "Technology_Description": "Bacteria frequently form intimate associations with a eukaryotic host where they may have critical roles in the development, behavior, and/or functions of their animal symbiont. While the underlying molecular mechanisms are poorly understood there is increasing evidence that the bacteria are employing proteins or molecules to send signals to their host. My goal is to understand the inter-kingdom signalling that occurs between a bacterium and its animal host using, as a model, the interaction between an entomopathogenic nematode (EPN) called Heterorhabditis and its symbiotic bacterium, Photorhabdus.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["706272"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Organisational public engagement with science and society (OPEST)"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["OPEST"], "Technology_Description": "There is a widely entertained, societal obligation on the part of scientific institutions to serve society with social impact and to engage citizens in research policy. This is also evidenced in recent policy documents (e.g. the European Union Framework Programme for Research and Innovation defines tackling societal challenges through research as one of the main priorities for Europe in the next decade), and by procedures of research funding bodies that require plans for engaging society with the results of the funded research. As a result, universities and scientific institutions face an imperative to facilitate \u2018pathways to impact\u2019 for their research as this can be an important factor in determining funding beyond serving society. While research on resources for PE has mainly focused on scientists, little attention has been paid to the institutional context in which PE occurs. OPEST \u2013 Organisational Public Engagement with Science and Technology will examine how RIs are engaging society. We aim to assemble an international database of comparable data on the culture of PE at institutions and to develop PE indicators for assessing institutional PE. The study has been implemented in Portugal in 2014. This project will allow conducting the study in the UK, Germany, Italy, Netherlands and the US. ", "To": ["2018-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-04-01"], "Project_ID": ["708434"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITAT DE BARCELONA"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Frobenius related invariants and singularities"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["Frobenius"], "Technology_Description": "This is a project in commutative algebra of positive characteristic, which has also many connections with algebraic geometry. The main goal of this project is to study the relations between some classes of rings that arise in prime characteristic, F-singularities, and three specific notions. These are the symmetric signature, a new invariant defined by the Experienced Researcher in his Ph.D. thesis; the generalized Hilbert-Kunz function, a recent generalization of the classical Hilbert-Kunz function studied intensively in prime characteristic algebra; and the FFRT property, a positive characteristic version of the notion of finite representation type, important in representation theory. As a guideline for the future research, eight concrete problems are stated and will be investigated by the Experienced Researcher with the help of the Supervisor. The strategy to complete this task include the acquisition of new knowledge, which will be obtained, among other things, also through the organization of weekly seminars with the collaboration of the host institution. The arguments of this project, F-singularities in particular, are important topics in commutative algebra and algebraic geometry which are developing and growing fast in these years, especially in the USA and in Japan. As a further way to promote the development of these topics also in Europe, the Experienced Researcher and the Supervisor plan to organize a small workshop which will take place in the host institution at the end of the fellowship.", "To": ["2019-02-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-02-15"], "Project_ID": ["701807"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITAT DE BARCELONA"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Combinatorics in Transcendental Dynamics"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["CoTraDy"], "Technology_Description": "Complex dynamics studies the evolution of a complex manifold under the action of a holomorphic map. In this proposal we study the dynamical systems generated by transcendental (either entire or meromorphic) maps acting on the complex plane. By using a wide range of classic and new techniques, we investigates epecially the combinatorics of these maps: that is to say, we build relations between the dynamics of the transcendental map on some specific subset of the complex plane and the dynamics of the shift map on the space of infinite sequences over the integers. Combinatorics in this setting is a powerful tool to understand the dynamics of transcendental maps and to understand the structure of specific families of transcendental maps. The study of combinatorics for transcendental maps is also likely to offer new insights in the combinatorics for rational maps and possibly in other areas of complex dynamical systems, like the systems generated by the iteration of holomorphic maps on manifolds with more than one complex dimension.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["703269"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITAT DE BARCELONA"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Cosmology with future large-scale surveys"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["COSMOFLAGS"], "Technology_Description": "New challenges for large galaxy surveys:", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["706896"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["FORSCHUNGSVERBUND BERLIN EV", "UNIVERSITAT DE VALENCIA", "UNIVERSITEIT TWENTE", "CONSIGLIO NAZIONALE DELLE RICERCHE", "UNIVERSITAET AUGSBURG", "UNIVERSIDAD POLITECNICA DE MADRID", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "TOSHIBA RESEARCH EUROPE LIMITED", "CHALMERS TEKNISKA HOEGSKOLA AB"], "EU_Contribution": ["EUR 3 855 693,24"], "Project_Title": ["Dynamic electromechanical control of semiconductor nanostructures by acoustic fields"], "Total_Cost": ["EUR 3 855 693,24"], "Country": ["Germany", "Spain", "Netherlands", "Italy", "Germany", "Spain", "France", "United Kingdom", "United Kingdom", "Sweden"], "Project_ACR": ["SAWTrain"], "Technology_Description": "The dynamic modulation of semiconductor structures using vibrations provides a powerful tool for the control of the materials properties required for novel functionalities. Surface acoustic waves (SAWs) with GHz-frequencies and micrometre-size wavelength can be generated using piezoelectric transducers fabricated with standard integrated circuit technology. Their small propagation velocity and high sensitivity to disturbances confined to a superficial region have long been exploited in electronic signal processing and sensor applications. The SAW-induced modulation of the electro-optical properties of semiconductor structures is now been used for a wide range of applications including advanced sensors, the control of chemical processes, as well as the coherent control of carriers, spins, photons, and phonons down to the single-particle level. The latter are presently been exploited for different functionalities including advanced waveguide modulators, tuneable optical resonators, and single-electron pumps and single-photon sources.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2015-06-01"], "Project_ID": ["642688"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["UNIVERSITAT DE VALENCIA"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Remotely quantifying vegetation productivity: exploiting sun-induced fluorescence-photosynthesis relationships through field and modelling methods"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["FLUOPHOT"], "Technology_Description": "During the past few years airborne/spaceborne detection and quantification of sun-induced chlorophyll fluorescence (SIF) emitted by terrestrial vegetation became possible at several narrow wavelengths. These improvements in Earth Observation technology offer huge possibilities to increase our knowledge on the basic functioning of the Earth\u2019s vegetation, i.e. the photosynthetic process of plants resulting in atmospheric carbon uptake. However, still some efforts are required for establishing well-funded relationships between SIF and photosynthesis under different plant physiological states. Hence, in order to improve the quantification of photosynthesis through SIF, the main aim of this proposal (FLUOPHOT) is to further establish the link between the SIF characteristics and both the actual and potential photosynthesis of the plant. This will be achieved by coupling dedicated field/laboratory measurements and campaigns with modelling activities. As a result of the planned activities, significant progress is foreseen in the remote quantification of vegetation productivity. FLUOPHOT strives to unravel fundamental SIF-photosynthesis systems at the leaf and canopy scale. These findings are in direct support of ESA\u2019s candidate Earth Explorer mission FLEX, and eventually will lead to unbiased global estimates of photosynthetic carbon uptake.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["701815"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITAT DE BARCELONA"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Innovation Systems in Financial Crisis: Technological Dynamics, Industrial Structure and Business Cycles"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["cRISys"], "Technology_Description": "This research project will investigate from an empirical, theoretical and normative perspective the impact of financial crisis on innovation systems, and in particular knowledge networks and technology clusters, and by extension, on technological trajectories, industrial dynamics and economic growth of afflicted EU economies. It will also explore the latent link between technological dynamics and business cycles, and examine to what extent a strategic mix of RTDI, industrial and regional policies can address structural causes of crises and foment techno-economic development by building the capacities of innovation systems and bridging the technology gap. ", "To": ["2017-06-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-07-01"], "Project_ID": ["659530"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITY OF NEWCASTLE UPON TYNE", "UNIVERSIDAD DE LLEIDA", "UNIVERSITAT DE VALENCIA", "UNIVERSITEIT VAN AMSTERDAM", "RIJKSUNIVERSITEIT GRONINGEN"], "EU_Contribution": ["EUR 1 044 000"], "Project_Title": ["Cultural Narratives of Crisis and Renewal"], "Total_Cost": ["EUR 1 044 000"], "Country": ["United Kingdom", "Spain", "Spain", "Netherlands", "Netherlands"], "Project_ACR": ["CRIC"], "Technology_Description": "The objective of the \u201cCultural Narratives of Crisis and Renewal\u201d project is to examine cultural production and cultural practices in periods of societal crisis at the turn-of the 20th Century on both sides of the Atlantic. The overarching aim of the project is to investigate the role of cultural production, not just as a vehicle to elaborate cohesive narratives in moments of crisis, but as a space to create alternative imaginaries for social renewal. We need to explore the changing nature of our societies and the reconfiguration of regional and/or national cultural landscapes into globalized real (and virtual) spaces that erode the cultural frontiers of the nation-state.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-01-01"], "Project_ID": ["645666"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["UNIVERSITAT DE VALENCIA", "UNIVERSITAT DE VALENCIA"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["HYBRID MAGNETIC SUPERCAPACITORS"], "Total_Cost": ["EUR 150 000"], "Country": ["Spain", "Spain"], "Project_ACR": ["Hy-MAC"], "Technology_Description": "The purpose of Hy-MAC is to assess both technical and economic viability of using magnetic nanocomposites based on the combination of carbon nanoforms (graphene) with magnetic nanoparticle as hybrid supercapacitors. These hybrid magnetic materials have shown to exhibit unique supercapacitive properties, which can be significantly enhanced by application of an external magnetic field. Thus, the specific capacitance increases up to a 500% by applying an external magnetic field. Taking advantage of these results, in this proposal we plan to fabricate and test prototype supercapacitive devices exhibiting better performances than those reported for commercial supercapacitors.", "To": ["2017-11-30, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2015 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["713704"], "Call_for_Proposal": ["ERC-2015-PoC"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA", "UNIVERSITY COLLEGE LONDON", "UNIVERSITAT DE BARCELONA", "BEN-GURION UNIVERSITY OF THE NEGEV", "STICHTING VU", "UNIVERSITY OF DURHAM", "MEDICAL RESEARCH INFRASTRUCTURE DEVELOPMENT AND HEALTH SERVICES FUND BY THE SHEBA MEDICAL CENTER", "NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO", "MOTEK MEDICAL B.V."], "EU_Contribution": ["EUR 3 911 673,24"], "Project_Title": ["Perception and Action in Complex Environments"], "Total_Cost": ["EUR 3 911 673,24"], "Country": ["France", "Italy", "United Kingdom", "Spain", "Israel", "Netherlands", "United Kingdom", "Israel", "Netherlands", "Netherlands"], "Project_ACR": ["PACE"], "Technology_Description": "The PACE research and training programme sits at the interface between basic science, technology and clinics, in order to unveil how humans control and adapt their movements in complex, naturalistic environments. Such a research agenda has major consequences for understanding how these movements are impacted by specific brain insults and how these impairments can be compensated for via new rehabilitation methods. Improving rehabilitation programmes for sensory and motor disabilities across the lifespan is a major societal challenge in western countries and many obstacles need to be overcome. To provide but one example, with regard to eye-hand coordination of upper limb movement remaining abilities are rarely assessed in stroke patients or sensory-disabled children and this impacts both prognostic estimation and rehabilitation. New technologies, such as robotics or virtual reality, provide an exciting change in perspective to transfer state-of-the-art knowledge from basic research on sensorimotor transformation into the clinical domain. To meet these societal challenges, it is crucial to train a new generation of early-stage researchers in a programme such as PACE where fundamental and applied/clinical research are effectively integrated via collaborative research, doctoral secondments and theoretical courses \u2013 in other words, one in which clinicians, neuroscientists, theoreticians and engineers can contribute around a well-defined problem: how humans acquire, lose and recover movement performance. With 8 academic, 1 clinical and 1 private beneficiaries, and 5 partner organizations (4 industrial, 1 in science communication), PACE structures a training and research programme that is both highly interdisciplinary and intersectoral. Our goal is to meet both fundamental and clinical well-identified challenges as well as preparing young scientists for future european research & development in the fields of human movement studies and rehabilitation medicine.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations", "Chiara Andreoli", "Tel.: +3901071781854", "Fax: +39 010 7170817", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-04-01"], "Project_ID": ["642961"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["UNIVERZITA KARLOVA", "FONDAZIONE ENI ENRICO MATTEI", "LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "FONDATION JEAN-JACQUES LAFFONT,TOULOUSE SCIENCES ECONOMIQUES"], "EU_Contribution": ["EUR 2 115 000"], "Project_Title": ["Global Excellence in Modelling of Climate and Energy"], "Total_Cost": ["EUR 2 115 000"], "Country": ["Czech Republic", "Italy", "United Kingdom", "United Kingdom", "France"], "Project_ACR": ["GEMCLIME"], "Technology_Description": "The global GEMCLIME project focuses on major aspects of energy economics and climate change, which is a prime example of an important global and complex scientific and policy problem. GEMCLIME covers the drivers of climate change, the examination of climate change and energy-related risks and vulnerabilities, the valuation of economic impacts of climate change mitigation and adaptation policies, and the investigation of major policy responses to global climate and energy challenges. GEMCLIME follows an integrated approach to modelling the impacts of climate and energy policies. The analysis of drivers, impacts, and responses to climate change attributes particular attention to the economics of renewable energies and the valuation of non-marketed goods. While GEMCLIME is focused on fundamental economic research, our results also provide support to evidence-based policy. GEMCLIME brings together both globally and regionally the most excellent institutions and researchers with wide-ranging research experience in the context of a collaborative scheme of research exchanges and networking. The members of the consortium share their skills and knowledge from the areas of climate change, energy, resource, health, environmental, and agricultural economics, while drawing on the expertise of participants in financial economics, applied macroeconomics, microeconomics, and econometrics. Our consortium also includes researchers and academics from non-economic disciplines, including political scientists, sociologists, lawyers, environmental scientists, and other scientists related to climate and energy. The reciprocal transfer of knowledge between the members of the consortium is supported by a staff exchange including senior research fellows, professors, early-career academics, and doctoral students. Our global project aims at supporting research mobility between the EU on one side, and the USA, Canada, New Zealand, Australia, South Africa, Singapore, and Chile on the other side.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Czech Republic"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2016-10-01"], "Project_ID": ["681228"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["LINKOPINGS UNIVERSITET", "THE UNIVERSITY OF SHEFFIELD", "RANPLAN WIRELESS NETWORK DESIGN LTD", "IQUADRAT INFORMATICA SL"], "EU_Contribution": ["EUR 634 500"], "Project_Title": ["Deploying High Capacity Dense Small Cell Heterogeneous Networks"], "Total_Cost": ["EUR 634 500"], "Country": ["Sweden", "United Kingdom", "United Kingdom", "Spain"], "Project_ACR": ["DECADE"], "Technology_Description": "Broadband mobile networks are experiencing exponential traffic growth. It is predicted that this trend will continue in the next five to ten years with an estimated compound annual growth rate of 0.6 to 1.0. Hence the traffic (mostly data) carried by a mobile operator\u2019s network in 2022 could be over 1000 times of that in 2012. This traffic growth presents a huge challenge to both the mobile industry and to academic researchers.", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-08-01"], "Project_ID": ["645705"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS", "STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS"], "EU_Contribution": ["EUR 149 750"], "Project_Title": ["A treatment for BRAF inhibitor resistant melanoma"], "Total_Cost": ["EUR 149 750"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["2MoveMate4Melanoma"], "Technology_Description": "Some 50% of human melanoma tumors have activating mutations in the BRAF gene. BRAF inhibitor drugs given either alone or in combination with MEK inhibitors have improved progression-free and overall survival in patients with BRAF mutant metastatic melanoma. However, drug resistance invariably limits the duration of clinical benefit of such treatments and is almost always associated with re-activation of signaling through the MAP kinase pathway in the presence of drug due to secondary mutations in the pathway. This highlights the urgent need to develop strategies to treat melanomas that have developed resistance to BRAF and/or MEK inhibitors. ", "To": ["2017-10-31, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2015 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2016-05-01"], "Project_ID": ["712951"], "Call_for_Proposal": ["ERC-2015-PoC"]}, -{"Partners": ["COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "BUNDESANSTALT FUER GEOWISSENSCHAFTEN UND ROHSTOFFE", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "THE UNIVERSITY OF READING", "STIFTELSEN NORSAR", "UNIVERSITA DEGLI STUDI DI FIRENZE", "DEUTSCHES ZENTRUM FUER LUFT - UND RAUMFAHRT EV", "KONINKLIJK NEDERLANDS METEOROLOGISCH INSTITUUT-KNMI", "LEIBNIZ-INSTITUT FUR ATMOSPHARENPHYSIK EV AN DER UNIVERSITAT ROSTOCK", "ANDOYA SPACE CENTER AS", "INSTITUTET FOR RYMDFYSIK", "NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU", "USTAV FYZIKY ATMOSFERY AV CR, v.v.i.", "Euro-Mediterranean Seismological Centre", "UNIVERSITE DE LA REUNION", "UNIVERSITAET BERN", "TEL AVIV UNIVERSITY", "NATIONAL UNIVERSITY OF IRELAND MAYNOOTH", "VEDURSTOFA ISLANDS", "UNIVERSITY OF ANTANANARIVO", "INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA PAMANTULUI", "FUNDACAO GASPAR FRUTUOSO", "CENTRE NATIONAL DE LA CARTOGRAPHIEET DE LA TELEDETECTION"], "EU_Contribution": ["EUR 2 985 250"], "Project_Title": ["Atmospheric dynamics Research InfraStructure in Europe"], "Total_Cost": ["EUR 3 242 382,50"], "Country": ["France", "Germany", "France", "United Kingdom", "Norway", "Italy", "Germany", "Netherlands", "Germany", "Norway", "Sweden", "Norway", "Czech Republic", "France", "France", "Switzerland", "Israel", "Ireland", "Iceland", "Madagascar", "Romania", "Portugal", "Tunisia"], "Project_ACR": ["ARISE2"], "Technology_Description": "It has been robustly demonstrated that variations in the circulation of the middle atmosphere influence weather and climate throughout the troposphere all the way to the Earth\u2019s surface. A key part of the coupling between the troposphere and stratosphere occurs through the propagation and breaking of planetary-scale Rossby waves and gravity waves. Limited observation of the middle atmosphere and these waves in particular limits the ability to faithfully reproduce the dynamics of the middle atmosphere in numerical weather prediction and climate models. ARISE2 capitalizes upon the work of the EU-funded first ARISE project combining for the first time international networks with complementary technologies such as infrasound, lidar and airglow. This joint network provided advanced data products that started to be used as benchmarks for weather forecast models. The ARISE network also allows enhanced and detailed monitoring of other extreme events in the Earth system such as erupting volcanoes, magnetic storms, tornadoes and tropical thunderstorms. In order to improve the ability of the network to monitor atmospheric dynamics, ARISE2 proposes to extend i) the existing network coverage in Africa and the high latitudes, ii) the altitude range in the stratosphere and mesosphere, iii) the observation duration using routine observation modes, and to use complementary existing infrastructures and innovative instrumentations. Data will be collected over the long term to improve weather forecasting to monthly or seasonal timescales, to monitor atmospheric extreme events and climate change. Compared to the first ARISE project, ARISE2 focuses on the link between models and observations for future assimilation of data by operational weather forecasting models. Among the applications, ARISE2 proposes infrasound remote volcano monitoring to provide notifications to civil aviation. The data portal will provide high-quality data and advanced data products to a wide scientific community.", "To": ["2018-08-31, ongoing project |"], "Meta": [""], "Topic_s": ["INFRADEV-1-2014 - Design studies"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Other", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2015-09-01"], "Project_ID": ["653980"], "Call_for_Proposal": ["H2020-INFRADEV-1-2014-1"]}, -{"Partners": ["UNIVERSITAT ROVIRA I VIRGILI", "KOZEP-EUROPAI EGYETEM", "ASOCIACION GITANA DE MUJERES DROM KOTAR MESTIPEN DE BARCELONA", "UNIVERSITAT DE BARCELONA", "UNIVERSITAT AUTONOMA DE BARCELONA", "BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY", "THE UNIVERSITY OF AUCKLAND", "QUEENSLAND UNIVERSITY OF TECHNOLOGY - QLD QUT", "UFSCar"], "EU_Contribution": ["EUR 391 500"], "Project_Title": ["Overcoming Inequalities in Schools and Learning Communities: Innovative Education for a New Century"], "Total_Cost": ["EUR 499 500"], "Country": ["Spain", "Hungary", "Spain", "Spain", "Spain", "United States", "New Zealand", "Australia", "Brazil"], "Project_ACR": ["SALEACOM"], "Technology_Description": "Overcoming Inequalities in Schools and Learning Communities: Innovative Education for a New Century (SALEACOM here after) proposes the collaboration between 7 research groups (Australia, Brazil, New Zealand, Hungary, South Africa, Spain, USA) and 1 non academic institution (Drom Kotar Mestipen) with a global scope to address educational and social exclusion in schools and learning communities. SALEACOM seeks to create an International Research Network that has the following aims: (i) to increase worldwide cooperation in the study of successful actions with children and youth systematically underserved; (ii) to provide high-quality training programs for teachers and educational researchers aiming at overcoming inequalities; (iii) to develop interdisciplinary solutions for and with learners most heavily affected by inequalities, including access and quality of higher education; (iv) to design strengths-based methodologies for international comparative research to further the impact of research on the lives of students who have been historically excluded (v) to create a global program of successful educational actions to be implemented across educational systems. To promote coherent and effective cooperation among the research team, it accounts for the inclusion of researchers across disciplines, stages in their careers and cultures, committed to conducting strengths-based international research to further impact the lives of students who have been traditionally unsuccessful in educational contexts. To maximise the research outcomes of this proposal, researcher exchanges are based on partners\u2019 complementarities in skills, methodological expertise and knowledge of several excluded populations that face similar challenges globally (i.e. Roma, Indigenous populations, African American, among others.). In parallel to developing interdisciplinary successful educational actions in schools and learning communities, we will explore paradigms, principles and practices.", "To": ["2017-12-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-01-01"], "Project_ID": ["645668"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON", "UNIVERSITAT DE BARCELONA", "STICHTING LIBER", "UNIVERSITAT WIEN", "UNITED NATIONS ECONOMIC COMMISSION FOR LATIN AMERICA AND THE CARIBBEAN"], "EU_Contribution": ["EUR 496 582"], "Project_Title": ["Leaders Activating Research Networks: Implementing the LERU Research Data Roadmap and Toolkit"], "Total_Cost": ["EUR 496 582,50"], "Country": ["United Kingdom", "Spain", "Netherlands", "Austria", "Chile"], "Project_ACR": ["LEARN"], "Technology_Description": "We live in the age of the \u2018data deluge\u2019, where digital technology enables us to store petabytes of data and to make that available for sharing as open data. Sharing data has the potential to revolutionise the way that researchers work. It avoids costly duplication in the collecting of data and enables research collaborations across the world which otherwise would not be possible.", "To": ["2017-05-31, closed project"], "Meta": [""], "Topic_s": ["INFRASUPP-7-2014 - e-Infrastructure policy development and international cooperation"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2015-06-01"], "Project_ID": ["654139"], "Call_for_Proposal": ["H2020-INFRASUPP-2014-2"]}, -{"Partners": ["UNIVERSITAT DE BARCELONA"], "EU_Contribution": ["EUR 239 191,20"], "Project_Title": ["Contextualising psychosocial wellbeing and mental health within sociocultural dynamics"], "Total_Cost": ["EUR 239 191,20"], "Country": ["Spain"], "Project_ACR": ["PSYCHOCONTEXT"], "Technology_Description": "The lack of contextualization of the science and applications of mental health is the source of a large part of its criticisms. From the lack of research on how social dynamics influence the well-being of citizens, to the gaps in research and coordinated implementation of different disciplines involved in mental health in a changing environment, there are still many limitations for a contextualised and integrated view.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["654808"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["SCIENCE AND TECHNOLOGY FACILITIES COUNCIL", "STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS", "EUROPEAN MOLECULAR BIOLOGY LABORATORY", "Masarykova univerzita", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "CONSORZIO INTERUNIVERSITARIO RISONANZE MAGNETICHE DI METALLO PROTEINE", "INSTRUCT ACADEMIC SERVICES LIMITED", "UNIVERSITEIT UTRECHT", "LUNA SAS", "ISTITUTO NAZIONALE DI FISICA NUCLEARE"], "EU_Contribution": ["EUR 3 981 125"], "Project_Title": ["World-wide E-infrastructure for structural biology"], "Total_Cost": ["EUR 3 981 125"], "Country": ["United Kingdom", "Netherlands", "Germany", "Czech Republic", "Spain", "Italy", "United Kingdom", "Netherlands", "France", "Italy"], "Project_ACR": ["West-Life"], "Technology_Description": "The focus of structural biology is shifting from single macromolecules produced by simpler prokaryotic organisms, to the macromolecular machinery of higher organisms, including systems of central relevance for human health. Structural biologists are expert in one or more techniques. They now often need to use complementary techniques in which they are less expert. Instruct supports them in using multiple experimental techniques, and visiting multiple experimental facilities, within a single project.", "To": ["2018-10-31, ongoing project"], "Meta": [""], "Topic_s": ["EINFRA-9-2015 - e-Infrastructures for virtual research environments (VRE)"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Other", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations"], "From": ["2015-11-01"], "Project_ID": ["675858"], "Call_for_Proposal": ["H2020-EINFRA-2015-1"]}, -{"Partners": ["UNIVERSITAT DE BARCELONA", "KOBENHAVNS UNIVERSITET", "DEMOCRITUS UNIVERSITY OF THRACE", "FERA SCIENCE LIMITED"], "EU_Contribution": ["EUR 526 500"], "Project_Title": ["KNOWLEDGE FOR PESTICIDES CONTROL"], "Total_Cost": ["EUR 526 500"], "Country": ["Spain", "Denmark", "Greece", "United Kingdom"], "Project_ACR": ["KNOWPEC"], "Technology_Description": "KKNOWPEC, Knowledge for pesticides control, aims to create a transnational research network between Europe and Latin America focused on the challenge of unwanted pesticides in the environment. KNOWPEC wants to identify the occurrence and fate of banned and toxic pesticides in drinking and natural waters in agricultural areas of Latin America where knowledge on occurrence and risk is scarce. KNOWPEC wants to assess the environmental and potential human risks of the pesticides detected, and to provide solutions for both reducing pollution at source, and remediating contaminated water. Together, KNOWPEC will promote the sharing of knowledge at each step from pesticide analysis, toxicity and risk assessment to advanced treatment technologies that jointly enables the design of sustainable solutions to each pesticide pollution problem. Moreover, we want to create the tools of information and networking for a source of collaboration between European and Latin America institutions under the framework of the environmental and human protection from pesticides. ", "To": ["2020-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-07-01"], "Project_ID": ["690618"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["UNIVERSIDAD COMPLUTENSE DE MADRID", "UNIVERSITAT DE VALENCIA", "ASTON UNIVERSITY", "POLITECHNIKA WROCLAWSKA", "OPTEGRA MVZ GMBH"], "EU_Contribution": ["EUR 2 484 775,44"], "Project_Title": ["European Dry Eye Network"], "Total_Cost": ["EUR 2 484 775,44"], "Country": ["Spain", "Spain", "United Kingdom", "Poland", "Germany"], "Project_ACR": ["EDEN"], "Technology_Description": "EDEN is a platform for the training and career development of 10 early-stage researchers (ESRs) in Vision Sciences. It coordinates research and training collaboration among 4 leading academic institutions in Europe, providing for a new combination of in-depth expertise from different countries. Furthermore, to strengthen the contact with the industrial world, the network has the following partners: (1) large company of hospitals, 1 SME that provides advance ophthalmic devices for ocular examination and (2) large companies specialized in eye-care products. It emphasises experience-based training through cross-disciplinary research projects that will analyse the lacrimal functional unit with state-of-the-art technology and assess the structural and physiological changes occurring in Dry Eye Disease (DED) patients. This will spur the generation of newer metrics to better differentiate between normal and DED patients. Further benefits include improvements in DED diagnosis and monitoring, studies on the effect of various DED treatments, development of DED aetiology-specific treatments and exploration of the risk factors that favour development of the disease or intensify its symptoms.", "To": ["2019-02-28, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-EJD - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-EJD)"], "Funding_scheme": ["MSCA-ITN-EJD - European Joint Doctorates"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-03-01"], "Project_ID": ["642760"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["EUROPEAN MOLECULAR BIOLOGY LABORATORY", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "LEIBNIZ-INSTITUT FUR PFLANZENBIOCHEMIE", "UNIVERSITAT DE BARCELONA", "THE UNIVERSITY OF BIRMINGHAM", "CONSORZIO INTERUNIVERSITARIO RISONANZE MAGNETICHE DI METALLO PROTEINE", "UNIVERSITEIT LEIDEN", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "UPPSALA UNIVERSITET", "BIOBANKS AND BIOMOLECULAR RESOURCES RESEARCH INFRASTRUCTURE CONSORTIUM (BBMRI-ERIC)", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE", "SWISS INSTITUTE OF BIOINFORMATICS", "CENTRO DI RICERCA SVILUPPO E STUDI SUPERIORI IN SARDEGNA SOCIETA' A RESPONSABILITA' LIMITATA"], "EU_Contribution": ["EUR 7 697 733,75"], "Project_Title": ["PhenoMeNal: A comprehensive and standardised e-infrastructure for analysing medical metabolic phenotype data"], "Total_Cost": ["EUR 8 018 723,75"], "Country": ["Germany", "United Kingdom", "Germany", "Spain", "United Kingdom", "Italy", "Netherlands", "United Kingdom", "Sweden", "Austria", "France", "France", "Switzerland", "Italy"], "Project_ACR": ["PhenoMeNal"], "Technology_Description": "In the coming decade a significant number of the 500.000.000 European (EU/EEA) citizens will have their genome determined routinely. This will be complemented with much cheaper (currently ~20 Euro per measurement) acquisition of the metabolome of biofluids (e.g. urine, saliva, blood plasma) which will link the genotype with metabolome data that captures the highly dynamic phenome and exposome of patients. Having such low cost solutions will enable, for the first time, the development of a truly personalised and evidence-based medicine founded on hard scientific measurements. The exposome includes the metabolic information resulting from all the external influences on the human organism such as age, behavioural factors like exercise and nutrition or other environmental factors. ", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["EINFRA-1-2014 - Managing, preserving and computing with big research data"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Germany"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations"], "From": ["2015-09-01"], "Project_ID": ["654241"], "Call_for_Proposal": ["H2020-EINFRA-2014-2"]}, -{"Partners": ["UNIVERSITAT DE BARCELONA", "UNIVERSITAT DE BARCELONA"], "EU_Contribution": ["EUR 149 950"], "Project_Title": ["Personified Self Interaction"], "Total_Cost": ["EUR 149 950"], "Country": ["Spain", "Spain"], "Project_ACR": ["PSI"], "Technology_Description": "This proof of concept is based on the ERC Advanced Grant TRAVERSE (2009-2015). It will exploit immersive virtual reality in a new form of psychological clinical intervention akin to Gestalt Therapy. The primary aim of this Proof of Concept project is to generate a business model that would allow us to diffuse our technology to thousands of counsellors and psychologists around the world. In order to accomplish that we commission further trials to extend the evidence base of the approach, investigate through market research the extension of the technique for business practice, develop a commercial prototype with consumer equipment that would be low cost but high quality, exhibit our product at international conferences, and make the system available on loan to psychologists or counsellors who wished to try it, and generally start the process of diffusion. Moreover, we that our low cost system incorporates patentable inventions that would be investigated in an IP strategy. Through this approach we will develop the Business Model and a draft Business Plan for mass take up of our applications.", "To": ["2017-12-31, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2015 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-07-01"], "Project_ID": ["712984"], "Call_for_Proposal": ["ERC-2015-PoC"]}, -{"Partners": ["UNIVERSITE DU LUXEMBOURG", "UNIVERSITA DEGLI STUDI DI TORINO", "ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA", "THE UNIVERSITY OF HUDDERSFIELD", "INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE", "APIS HRISTOVICH EOOD", "NOMOTIKA SRL", "DLVSYSTEM SRL"], "EU_Contribution": ["EUR 1 152 000"], "Project_Title": ["MIREL - MIning and REasoning with Legal texts"], "Total_Cost": ["EUR 1 264 500"], "Country": ["Luxembourg", "Italy", "Italy", "United Kingdom", "France", "Bulgaria", "Italy", "Italy"], "Project_ACR": ["MIREL"], "Technology_Description": "The management of large repositories of norms, and the semantic access and reasoning to these norms are key challenges in Legal Informatics. The MIREL project will create an international and inter-sectorial network to define a formal framework and to develop tools for MIning and REasoning with Legal texts, with the aim of translating these legal texts into formal representations that can be used for querying norms, compliance checking, and decision support. The development of the MIREL framework and tools will be guided by the needs of three industrial partners, and validated by industrial case studies. MIREL promotes mobility and staff exchange between SMEs to academies in order to create an inter-continental interdisciplinary consortium in Law and Artificial Intelligence areas including Natural Language Processing, Computational Ontologies, Argumentation, and Logic & Reasoning.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Luxembourg"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Denise Ogden", "Tel.: +44-1484-473192", "Fax: +44-1484-472682", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-01-01"], "Project_ID": ["690974"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["ACADEMISCH ZIEKENHUIS LEIDEN", "STICHTING INSTITUTE FOR HUMAN ORGAN AND DISEASE MODEL TECHNOLOGIES", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM", "UNIVERSIDAD DE ZARAGOZA"], "EU_Contribution": ["EUR 520 472,50"], "Project_Title": ["Organ on Chip in Development"], "Total_Cost": ["EUR 520 472,50"], "Country": ["Netherlands", "Netherlands", "Germany", "France", "Belgium", "Spain"], "Project_ACR": ["ORCHID"], "Technology_Description": "Organ-on-chip technology will revolutionize the healthcare domain by offering new and ground breaking solutions to different industries and especially for regenerative medicine and medication.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-03-2017 - FET-Open Coordination and Support Actions"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["766884"], "Call_for_Proposal": ["H2020-FETOPEN-3-2017"]}, -{"Partners": ["THE UNIVERSITY OF LIVERPOOL", "UNIVERSITY OF PLYMOUTH", "INNOVATION FOR AGRICULTURE", "CONSIGLIO NAZIONALE DELLE RICERCHE", "AINIA", "BRETAGNE DEVELOPPEMENT INNOVATION", "SYSTEMS RESEARCH INSTITUTE OF THE POLISH ACADEMY OF SCIENCES IBS PAN", "UNIVERSITAT POLITECNICA DE VALENCIA", "UNIVERSITE DE LORRAINE", "UNIVERSITE TOULOUSE 1 CAPITOLE", "LINKING ENVIRONMENT AND FARMING LBG", "KERNOCK PARK PLANTS LIMITED", "FEDERACION EMPRESARIAL DE AGROALIMENTACION DE LA COMUNIDAD VALENCIANA(FEDACOVA)", "AGENZIA LUCANA DI SVILUPPO E DI INNOVAZIONE IN AGRICOLTURA"], "EU_Contribution": ["EUR 1 332 000"], "Project_Title": ["Enhancing and implementing Knowledge based ICT solutions within high Risk and Uncertain Conditions for Agriculture Production Systems"], "Total_Cost": ["EUR 1 332 000"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom", "Italy", "Spain", "France", "Poland", "Spain", "France", "France", "United Kingdom", "United Kingdom", "Spain", "Italy"], "Project_ACR": ["RUC-APS"], "Technology_Description": "Increasingly challenging global and environmental requirements have resulted in agricultural systems coming under increasing pressure to enhance their resilience capabilities in order to respond to the abrupt changes in resource quality, quantity and availability, especially during unexpected environmental circumstances, such as uncertain weather, pests and diseases, volatile market conditions and commodity prices. Therefore, integrated solutions are necessary to support the whole food agricultural life-cycle value chain. Solutions necessarily must consider the products\u2019 cycle, as well as each of the value chain stages. Thus, managing risks and the uncertain availability of information will lead farmers to take advantage of these managerial, technical and social based-solutions. This implies the need for innovative technology-based knowledge management system to capture the agricultural information, at a variety of regional locations, in terms of collecting, storing, processing, and disseminating information about uncertain environmental conditions that affect agricultural decision-making production systems. Hence, from the genetic design of the seed, till their planting and harvest processes, RUCAPS provides knowledge of the full agricultural life-cycle based-decision making process to realise the key impacts of every stage of the agriculture-related processes. Therefore, RUCAPS implies the development of a high impact research project in order to integrate real-life based agriculture requirements, alternative land management scenarios, unexpected weather and environmental conditions as well as supporting innovation in the development of agriculture production systems, operations, logistics and supply chain management and the impact of these systems and processes over the end-users and customers. This is to be conceived through the integration of standard and customised solutions for facilitating the collaborative engagement within the agriculture value chain.", "To": ["2020-10-02, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other", "Research Organisations", "Research Organisations", "Other", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2016-10-03"], "Project_ID": ["691249"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["UNIVERSITAT DE BARCELONA"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Politicians\u2019 traits and public policies: learning how personal features influence fiscal outcomes"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["POLITRAITS"], "Technology_Description": "Nowadays there is little doubt that maximizing social welfare is not the sole goal of policymakers. Policy choices such as the level of taxation and spending are at the core of public economics. A positive approach to this field takes into account the fact that budgets and policies are set by political agents who are office-seekers. Early studies on political economy have focused on institutional factors, voters\u2019 preferences, interests groups, and party ideology as major drivers of public policies. But a growing number of theoretical and empirical studies have started to examine the particular features of political leaders (e.g. gender or ethnicity) as relevant determinants of economic outcomes and policies.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["749547"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAT DE VALENCIA"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Commissioning, first tests and upgrade of a high-power S-Band Radio Frequency (RF) system for R+D of high-gradient normal-conducting accelerating cavities in breakdown science and RF conditioning"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["HGRF-IFIC"], "Technology_Description": "New Radio Frequency (RF) High-Gradient (HG) knowledge and technology in normal conducting accelerator structures has been developed by the accelerator Physics community in the recent years in X-Band frequency. Significant progress has been made to understand the RF high-gradient behavior, breakdown phenomena and cavities conditioning processes, but extensive R&D is still needed in this very interdisciplinary and phenomenology research area. This project proposes the commissioning and upgrade of a novel high-power RF system in S-Band to perform systematic breakdown studies and conditioning of cavities in this frequency range, in particular interesting for medical applications. The main challenge is the implementation of a hard real-time control of amplitude and phase at microsecond scale of the pulsed megawatt RF power delivered to the structures under test. The power delivery has to be done under stringent controlled and automated conditions in order to perform the conditioning and avoid permanent damage to the structures. In addition, a power boost upgrade of the system is envisaged to reach the power limits that medical high-gradient structures need to be pushed to. A close relation with industry partners is to be carried out in order to commission the new solid-state power modulator and test structures. The outcome of this R&D project can be crucial to make more compact linear accelerators, resulting in lower cost and size, which can have a potential impact in several applications: hadrontherapy facilities based on linear accelerators, which will be emphasized in this project due to its advantageous features; industrial applications such as cargo scanning; or scientific applications such as free-electron-lasers and Compton sources.", "To": ["2019-05-18, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-19"], "Project_ID": ["750871"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAT AUTONOMA DE BARCELONA", "KUNGLIGA TEKNISKA HOEGSKOLAN", "AERIS TECNOLOG\u00cdAS AMBIENTALES S.L.", "INNOVA BIC - BUSINESS INNOVATION CENTRE SRL", "MERGUS PROMOTION HANDELSBOLAG"], "EU_Contribution": ["EUR 688 500"], "Project_Title": ["ADVANCED MULTIFUNCTIONAL NANOSTRUCTURED MATERIALS APPLIED TO REMOVE ARSENIC IN ARGENTINIAN GROUNDWATER"], "Total_Cost": ["EUR 688 500"], "Country": ["Spain", "Sweden", "Spain", "Italy", "Sweden"], "Project_ACR": ["NANOREMOVAS"], "Technology_Description": "Daily intake of arsenic polluted water by cattle in Argentina is becoming of increasing concern, especially due to the important size of the livestock export market where EU is a main customer. Because natural forage or alfalfa grown without irrigation is used to feed livestock, drinking water is considered the main source of arsenic for cattle (several studies reveal arsenic concentrations in phreatic water samples above 0.15 mg/L, the level that suggest causing chronic intoxication in cattle). Therefore, as it has been demonstrated, there is a risk of exposure for the human health due to the introduction in the food chain through milk or meat. In view of arsenic toxicity and the large number of people exposed to its effects worldwide, there is a clear need for the implementation in remote exploitations of affordable and sustainable treatment methodologies to provide potable water to cattle. To face this problem and provide a solution, NANOREMOVAS pursues to develop and implement a pilot plant for the remote treatment of arsenic polluted waters based on the application of state-of-art advanced multifunctional nanostructured materials, already tested at the laboratory level. In this sense, NANOREMOVAS includes the cooperation between the industry and academia of partners from Europe and Argentina. Besides the required research and innovation to demonstrate the technical and economic feasibility of the developed water recycling technique, the seconded researchers will carry out a series of tasks and outreach activities, promoting entrepreneurship culture and support of young innovative companies in order to set-up technological partnerships within the water and livestock sector. Furthermore, NANOREMOVAS represents a significant contribution to knowledge and technology transfer from the academia to the industrial sector, through the partners well established reputation as transfer hubs, that will led to quickly creating designs and industrial equipment/processes/model", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["645024"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["CENTRO DE INVESTIGACION ECOLOGICA YAPLICACIONES FORESTALES CONSORCIO"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Resilience of Soil Stoichiometry in subartic soils under Temperature-Induced Soil Carbon Losses: Where does the N go?"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["StoiCa"], "Technology_Description": "Global warming can trigger enormous releases of carbon (C) from soils, with positive feedbacks to climate change. Northern high latitude soils can constitute a major contributor to this positive feedback loop. Climate change predictions are however still largely uncertain, partly due the lack of accurate representation of vegetation and soil microbial feedbacks and C and nitrogen (N) interactions. Warming enhances microbial mineralization of soil organic matter (SOM) (i.e. soil C outputs) to a higher degree than vegetation productivity (i.e. soil C inputs), resulting in large C losses from northern soils. Pioneer results point to proportional N losses in response to warming, which may be the key to this phenomenon. This project will combine the expertise of a multidisciplinary group of leading researchers on ecosystem stoichiometry, stable N isotopic methods and applied biotechnology with the existence of unique and established research sites in geothermal systems in Iceland to reveal the fate of N lost in response to warming, and uncover the mechanisms behind observed soil C losses. StoiCa will elucidate, for first time, three key knowledge gaps: (1) the rates, forms and mechanisms of N losses from arctic soils under warming; (2) the transient- and persistent responses and the warming-induced transitions from a closed to a leaky, open N cycle; (3) the shifts towards a more symbiotic N cycle and role of thermo-adapted mycorrhiza in stimulating plant growth. This proposal directly addresses two cross-cutting priorities of sustainable development and climate action from the H2020 Work Programme. It also represents an exceptional opportunity for the candidate to acquire the essential skills that she lacks and that will convert her into a highly competitive European researcher in climate change biogeochemistry, while obtaining intersectorial capacities that will open new career avenues.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["750252"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAT DE BARCELONA"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Unlocking the virtual body: Exploiting the symbiotic relationship between an avatar and its user to modify bodily experience and improve the outcome of eating disorder treatment"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["SYMBIOTIC BODY"], "Technology_Description": "Successfully fighting eating disorders (EDs), whose prevalence is rising and expected to be one of the highest-ranking causes of mental illness in the Western world by 2020 with ever-increasing costs of institutional healthcare in and beyond Europe, interdisciplinary efforts to elucidate their underlying, enigmatic, mechanism of body image disturbance, BID (the experience of one\u2019s body as fatter/larger than it actually is) and improving the effectiveness of existing evidence-based interventions are now imperative, also according to the European Council of EDs and the National Institute of Mental Health (USA). Substantial advances in this area crucially depend on improved understanding of disease mechanisms while extant treatment strategies are hindered by the lack of specified conceptual models underlying the mechanism driving the extremes of BID in EDs, causing huge costs to individuals and society at large. However, as reported in the top-tier journals, the applicant and co-workers\u2019 \u201callocentric lock\u201d model of EDs provides a rich conceptual framework for elucidating the source of BID and factors causing ED patients to be \u201clocked\u201d in a \u201cvirtual body\u201d (e.g. my body is fat) that they detest and differs from the real one. This interdisciplinary project (with integrated training), going beyond the state-of-the-art not only aims at a) providing further evidence for the existence of allocentric lock in EDs and b) assessing its neural bases, but also c) setting and tuning a virtual reality-based embodiment device able to unblock the \u201cvirtual body\u201d by exploiting the symbiotic relationship between an avatar and its user, and testing it in integrated first-line ED treatment approaches (randomized controlled clinical trial). The Symbiotic Body project work, also having the potential to open a path to a new vision of e-health (strategic H-2020 area) -e-mbodied health, will be disseminated and notified to the international scientific/clinical community and the general public.", "To": ["2020-01-11, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-12"], "Project_ID": ["745948"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAT DE BARCELONA"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Ramon Llull (1232-1316): A Vernacular Writer Between Christianity and Islam"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["Christianus Arabicus"], "Technology_Description": "Ramon Llull\u2019s Cent noms de D\u00e9u is the only versified work which entered the net of self-quotations and self-references which Llull used to promote and advertise his own production as a new alternative to his contemporary science and literature. In spite of his condemnation of troubadour lyric in his Book of Contemplation, Llull wrote many poems with a mnemonic-didactic purpose related to the learning of his epistemological system, i.e. the Art. Yet some his poems and some of his literary works are strongly related with contemporary literature and literary uses which he exploited and transformed to attract a wider audience. These literary \u2018traps\u2019 were a useful tool to spread the Art among all social classes, thus enhancing the fulfilment of Llull\u2019s project: the conversion of all the unbelievers. The new critical edition of this work will help advancing my research on why Llull used poetic forms albeit he despised them and will provide new materials for understanding the circulation of culture and of ideas in the Mediterranean area in the XIII-XIV centuries.", "To": ["2019-10-01, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-02"], "Project_ID": ["746221"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK"], "EU_Contribution": ["EUR 248 063,40"], "Project_Title": ["Photon-recycling for high-efficiency energy harvesting in GaAs photovoltaic devices on silicon"], "Total_Cost": ["EUR 248 063,40"], "Country": ["Ireland"], "Project_ACR": ["RECHARGE"], "Technology_Description": "The Internet of Things promises billions of connected sensors and devices measuring and reporting information about the world around us. Due to the limited lifetime of batteries, this vision will not be realised without energy harvesting solutions providing power autonomy to sensors, a topic specifically prioritised in the 2016-2017 Work programme of Horizon 2020 (page 100). This project aims to develop and demonstrate high-efficiency and low-cost GaAs photovoltaic energy harvesters as power sources for wireless sensors, and equip the fellow with the entrepreneurial competencies required to commercialise the results. ", "To": ["2020-06-04, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-05"], "Project_ID": ["746516"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAT DE BARCELONA"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Our Galaxy at full HD"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["Gal-HD"], "Technology_Description": "Some astrophysical mechanisms that are crucial for the evolution of our Galaxy, and of galaxies in general, like the assemblage of the Galactic halo, the spiral arms dynamics, and the star formation processes, are poorly understood. But this research field is on the verge of an important breakthrough thanks to the ESA Gaia mission that is gathering an unprecedented census of positions, distances, velocities and stellar properties for a billion stars. Now it is time that the European scientists exploit their output data. Our Galaxy at full High Definition (Gal-HD) is a project that will use the Gaia data releases and follow-up surveys to investigate key galaxy evolution processes. We will do this by detecting the signatures that they produce in the stellar phase-space of the Galaxy. Gal-HD will pioneer in: 1) the detection of Ultra Faint Dwarf Galaxies in the halo as probes for cosmological models, 2) the investigation of the large-scale kinematics of the disk and the nature of the spiral arms, 3) the study of the nearby kinematics as tracer of the local star formation. The project combines observational and theoretical astrophysics with data mining. The Experienced Researcher (ER) has deep expertise in Galactic dynamics, analysis of kinematic data and substructure detection tools. The Host Group is expert in Galactic astronomy, coordinates the development of the novel Gaia Archive and will train the ER on the Archive mining tools required. The strong preparation for the Gaia exploitation of the ER and the Host Group puts them in clear advantage to make a substantial contribution to the field and to be in the front lead of the Gaia science. This research will bring the ER closer to her long-term career goals of being a consolidated leading researcher. Gal-HD will also participate in preserving the European leadership in Galactic astronomy and space astrometry, and contribute to the Gaia scientific harvest that Europe has planned and invested for.", "To": ["2020-02-29, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["745617"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CENTRO DE INVESTIGACION COOPERATIVADE ENERGIAS ALTERNATIVAS FUNDACION", "UNIVERSITE DE BORDEAUX"], "EU_Contribution": ["EUR 161 590,22"], "Project_Title": ["Solid-state reactions for thermal energy storage"], "Total_Cost": ["EUR 161 590,22"], "Country": ["Spain", "France"], "Project_ACR": ["SOLSTORE"], "Technology_Description": "In this project proposal reversible solid-state chemical reactions (eutectoids, peritectoids) are proposed for the storing of thermal energy at high temperature (300-800 \u00b0C). The development of a novel heat storage concept, based on solid-solid reactions, proposed in this project, could contribute to open new scenarios in the thermal energy storage field. To the best of our knowledge, the use of this class of reactions for TES applications has not been explored so far. The goal of this study is the identification of solid-state reactions fulfilling a large number of scientific and technological requirements (high storage capacity, good thermal conductivity, mechanical and chemical stability, complete reversibility of a charging/discharging cycles etc.). ", "To": ["2019-03-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2017-03-15"], "Project_ID": ["752520"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK"], "EU_Contribution": ["EUR 1 416 000"], "Project_Title": ["APC Postdoctoral EXcellence Programme"], "Total_Cost": ["EUR 2 832 000"], "Country": ["Ireland"], "Project_ACR": ["APEX"], "Technology_Description": "APEX (APC Postdoctoral EXcellence) is an innovative intersectoral trans- disciplinary training, career development and mobility programme based at the APC Microbiome Institute, UCC, which focuses on the research area of gut microbiota and their role in human health and disease. APEX will offer 20 fellowships for incoming mobility with all fellows hosted in an APC academic host organisation: UCC, Teagasc, the Agriculture, Food and Development Authority (Teagasc) or the Cork Institute of Technology (CIT). ", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2016 - Co-funding of regional, national and international programmes"], "Funding_scheme": ["MSCA-COFUND-FP - Fellowship programmes"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["754535"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2016"]}, -{"Partners": ["UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK"], "EU_Contribution": ["EUR 187 866"], "Project_Title": ["Microbiota-immune interaction in colorectal cancer"], "Total_Cost": ["EUR 187 866"], "Country": ["Ireland"], "Project_ACR": ["IMMUNO_CRC"], "Technology_Description": "The human gastrointestinal tract harbours trillions of bacteria that have co-evolved to play important roles in health and disease, conferring immunological, metabolic and neurological benefits to the host. This assemblage is known as the Gut Microbiota and has been a focus of investigation over the last decade. Altered gut microbiota composition has been associated with colorectal cancer (CRC), and studies in germ-free mice established an important role for some gut microbiota members in oncogenesis outcome, tumour progression and response to therapy. Data from the host laboratory show that patients with CRC harbour specific gut microbiota sub-types, among which some are associated with distinct mucosal gene-expression profiles. Thus either directly or through their metabolites, these tumour-associated microbiota appear to differentially recruit and interact with host inflammatory cells, which we hypothesize may be involved in different outcomes of carcinogenesis. The presence of particular immune cells is known to be prognostic of clinical outcome, because it often creates a tumour-promoting environment. Therefore, strategies aimed at manipulating the tumour-associated microbiota in CRC represent a promising therapeutic approach for patients. IMMUNO-CRC\u2019s goal is to elucidate the mechanisms by which certain bacterial sub-types associated with CRC may alter immune function and influence clinical outcome. Using multicolour flow cytometry, I will analyse infiltrating immune cells characteristic of different inflammatory responses and microbiota sub-types. Histo-immunophenotyping analysis on tumour biopsies will determine their inflammation and cancer phenotype. Metabolomics will identify specific microbial metabolites involved in the regulation and progression of inflammation. Ultimately, this unique and innovative combination of techniques will pave the way for novel therapeutics targeting the human microbiota for cancer treatment.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["752047"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAT DE VALENCIA"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Single-Molecule Spintronics: a Coordination Chemistry Approach to Quantum Computing"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["SIMOF"], "Technology_Description": "The project proposed herein develops in the frame of the Coordination Chemistry approach to Molecular Magnetism and Molecular Spintronics, aiming at the design, synthesis and characterisation of new prototypes of multifunctional and multiresponsive molecular magnetic devices based on Single Ion Magnets (SIMs), as models of electro- and photoswitchable multiple Quantum Bits and Quantum Gates (QGs) for the physical implementation of Quantum Information Processing in the emerging field of Quantum Computation.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["748921"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK"], "EU_Contribution": ["EUR 187 866"], "Project_Title": ["Molecular Characterisation of Anthropogenic Secondary Organic Aerosols."], "Total_Cost": ["EUR 187 866"], "Country": ["Ireland"], "Project_ACR": ["MOCHA"], "Technology_Description": "Secondary organic aerosol (SOA) accounts for a large fraction of atmospheric aerosol mass and can have significant effects on atmospheric composition, human health, and climate. However, considerable uncertainty exists on the chemical composition of SOA, as well as the sources and processes leading to its formation in the atmosphere. In this project state-of-the-art analytical techniques will be used to determine the molecular composition of secondary organic aerosols in ambient urban air and the identity of the precursor volatile organic compounds (VOCs). These field measurements will provide detailed information on VOCs and particle composition that can be linked to specific pollution sources, such as vehicle emissions and biomass burning. A detailed programme of simulation chamber experiments will also be conducted to investigate the formation of SOA from anthropogenic VOCs that most strongly influenced aerosol composition at the measurement site. The simulation chamber experiments will generate novel information on the reaction pathways for anthropogenic SOA formation that can be incorporated into atmospheric models dealing with both air quality and climate. Overall, the unique information obtained from this combined field and laboratory study is expected to contribute to a greatly improved understanding of the composition, sources and processes leading to organic aerosol formation in the atmosphere, and in turn, the impact of SOA on human health and climate. During this project, the Fellow will receive high quality training through research that will significantly improve scientific knowledge and provide a strong platform for building an independent research career. A wide range of complementary and transferable skills will also be developed to enhance future career prospects.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["751527"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAT DE BARCELONA"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Understanding the role of environmental and climatic changes in shaping subterranean diversity to preserve Europe\u2019s unique hidden biodiversity"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["HiddenLife"], "Technology_Description": "Climate warming and other anthropogenic perturbations are affecting ecosystems worldwide, contributing to the sixth mass extinction. Documenting and explaining a vanishing biodiversity are major challenges in evolutionary and ecological research, but understanding biodiversity is an essential step towards halting its loss and the degradation of ecosystem services, a headline target of EU 2020 biodiversity strategy. Caves are isolated and extreme habitats that, like oceanic islands, offer unparalleled opportunities for biodiversity research. Subterranean ecosystems are simpler than surface ones. Their stable climatic conditions, scarcity of food and absence of light drive the evolution of highly adapted fauna. Because of the difficulty to access and explore caves and the rarity of cave dwelling organisms, the study of the subterranean realm has lagged behind the research conducted in other experimental ecosystems. Despite of their reputedly stable climatic conditions, recent studies show that global warming may impact subterranean habitats by rising temperatures and, consequently, threatening troglobionts, which have low tolerance to temperature variations, causing the reduction of optimal habitat and driving narrowly distributed species to extinction. HIDDENLIFE project aims to improve our understanding of one of the top biodiversity hotspots in Europe\u2013the Dinarides, and its unique cave fauna, to ensure its conservation and future well-being. Through a multidisciplinary approach that combines state of the art molecular and statistical tools, I will investigate the systematics, phylogeography, and environmental preferences of three independent lineages of cave spiders. This will contribute to untangling the mechanisms that shaped their origin and present day diversity and distribution. By projecting potential distributions under predicted scenarios of global warming, I will predict future habitat suitability and assess vulnerability of this unique and fragile fauna.", "To": ["2019-06-04, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-05"], "Project_ID": ["749867"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAT DE VALENCIA"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Molecular glues for perovskite materials"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["PerovSAMs"], "Technology_Description": "This project aims at optimizing the interface between halide perovskites and different semiconductors through the use of self-assembled monolayers (SAMs). Such interface engineering will be applied to perovskite solar cells where SAMs will play the role of \u201cmolecular glues\u201d between the active perovskite layer and charge transport layers (n- and p-type metal oxides as well as organic semiconductors). Through the grafting and self-assembly of short bifunctional molecules, PerovSAMs will ensure a smooth and close contact at the interfaces, favouring charge transfer in the cell, thus minimizing losses and enhancing the power conversion efficiency (PCE). Furthermore, this versatile methodology will also be applied to perovskite nanocrystals (NCs). Surface functionalization of the NCs with SAMs will allow the formation of a perovskite shell with a different chemical composition creating core-shell quantum dots with superior photovoltaic properties, boosting the incipient field of perovskite NC-based solar cells.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["747599"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAT DE VALENCIA"], "EU_Contribution": ["EUR 159 126"], "Project_Title": ["Molecule for low diffusion TPCs for rare event searches"], "Total_Cost": ["EUR 159 126"], "Country": ["Spain"], "Project_ACR": ["MELODIC"], "Technology_Description": "One of the most promising technologies to search for neutrinoless double beta decay (0nubb) is a high pressure xenon gas (HPGXe) time projection chamber (TPC) with electroluminescent (EL) amplification. The key advantage of an EL HPGXe TPC is the capability to uniquely image the track of the two emitted electrons in a 0nubb event, together with high energy resolution. The current imaging performance is limited by the diffusion of the ionization electrons during drift. This proposal describes a research program to reduce diffusion by adding CH4 molecular additives to the xenon gas to improve the imaging capability in an EL HPGXe TPC enhancing the sensitivity to the 0nubb decay, within the context of the NEXT collaboration. Dr. Lopez March and the two supervisors Prof. Gomez Cadenas and Prof. Nygren propose to develop the project in two stages: 1) characterization of the CH4 molecular additive in a small detector at the University of Texas at Arlington (UTA), Outgoing Phase); 2) exploit the new gas mixture to perform the measurement of the topological signature with the NEXT-DEMO TPC at the Instituto de Fisica Corpuscular (SPAIN) and with the NEW TPC at the underground Laboratorio Subterr\\'aneo de Canfranc (LSC) (Return Phase). The objectives of the MELODIC project have been planned to boost the career development of the fellow. The overall training received by Dr. Lopez March in the proposed research project will give her independence and professional maturity. She will become a truly, multidisciplinary researcher capable of integrating different areas of research (operation of detectors and physics data analysis) making her uniquely trained for leading her own line of research.", "To": ["2019-09-17, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-18"], "Project_ID": ["740055"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAT DE BARCELONA", "UNIVERSITAT DE BARCELONA"], "EU_Contribution": ["EUR 1 835 220"], "Project_Title": ["Beyond Precision Cosmology: dealing with Systematic Errors"], "Total_Cost": ["EUR 1 835 220"], "Country": ["Spain", "Spain"], "Project_ACR": ["BePreSysE"], "Technology_Description": "Over the past 20 years cosmology has made the transition to a precision science: the standard cosmological model has been established and its parameters are now measured with unprecedented precision. But precision is not enough: accuracy is also crucial. Accuracy accounts for systematic errors which can be both on the observational and on the theory/modelling side (and everywhere in between). While there is a well-defined and developed framework for treating statistical errors, there is no established approach for systematic errors. The next decade will see the era of large surveys; a large coordinated effort of the scientific community in the field is on-going to map the cosmos producing an exponentially growing amount of data. This will shrink the statistical errors, making mitigation and control of systematics of the utmost importance. While there are isolated and targeted efforts to quantify systematic errors and propagate them through all the way to the final results, there is no well-established, self-consistent methodology. To go beyond precision cosmology and reap the benefits of the forthcoming observational program, a systematic approach to systematics is needed. Systematics should be interpreted in the most general sense as shifts between the recovered measured values and true values of physical quantities. I propose to develop a comprehensive approach to tackle systematic errors with the goal to uncover and quantify otherwise unknown differences between the interpretation of a measurement and reality. This will require to fully develop, combine and systematize all approaches proposed so far (many pioneered by the PI), develop new ones to fill the gaps, study and explore their interplay and finally test and validate the procedure. Beyond Precision Cosmology: Dealing with Systematic Errors (BePreSysE) will develop a framework to deal with systematics in forthcoming Cosmological surveys which, could, in principle, be applied beyond Cosmology.", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["725327"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["FUNDACAO D. ANNA SOMMER CHAMPALIMAUD E DR. CARLOS MONTEZ CHAMPALIMAUD", "FUNDACAO D. ANNA SOMMER CHAMPALIMAUD E DR. CARLOS MONTEZ CHAMPALIMAUD"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Neuroimmune activation as a novel therapeutic approach for IBD"], "Total_Cost": ["EUR 150 000"], "Country": ["Portugal", "Portugal"], "Project_ACR": ["NeurIMM"], "Technology_Description": "NeurIMM has been designed to investigate the commercial and technical viability of a novel, targeted therapy for Inflammatory Bowel Disease (IBD), based on a recently uncovered signaling axis between intestinal type 3 innate lymphoid cells (ILC3s) and enteric glial cells. This discovery by the team of Prof. Henrique Veiga-Fernandes in the ERC CoG grant 647274 \u2018GliaInnateSensing\u2019 was recently published in Nature (Ibiza et al, Nature 2016). NeurIMM proposes the use of a glial cell-derived immunomodulator to restore intestinal homeostasis, by inducing a tissue protective immune response. Importantly, this novel therapy will also promote tissue healing to reverse immune-cell mediated tissue damage, leading to improved outcomes for the patient. This could have major implications for patients suffering from IBD. In addition, this approach also has potential as an effective therapy against cancer, (pediatric) gastroenteritis and other inflammatory disorders.", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Portugal"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["764332"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["HELSINGIN YLIOPISTO", "HELSINGIN YLIOPISTO"], "EU_Contribution": ["EUR 2 420 429"], "Project_Title": ["Translational implications of the discovery of brain-draining lymphatics"], "Total_Cost": ["EUR 2 420 429"], "Country": ["Finland", "Finland"], "Project_ACR": ["BrainDrain"], "Technology_Description": "In 2010, 800 billion Euros was spent on brain diseases in Europe and the cost is expected to increase due to the aging population. \u2013 Here I propose to exploit our new discovery for research to alleviate this disease burden. In work selected by Nature Medicine among the top 10 \u201dNotable Advances\u201d and by Science as one of the 10 \u201dBreakthroughs of the year\u201d 2015, we discovered a meningeal lymphatic vascular system that serves brain homeostasis. We want to reassess current concepts about cerebrovascular dynamics, fluid drainage and cellular trafficking in physiological conditions, in Alzheimer\u2019s disease mouse models and in human postmortem tissues. First, we will study the development and properties of meningeal lymphatics and how they are sustained during aging. We then want to analyse the clearance of macromolecules and protein aggregates in Alzheimer\u2019s disease in mice that lack the newly discovered meningeal lymphatic drainage system. We will study if growth factor-mediated expansion of lymphatic vessels alleviates the parenchymal accumulation of neurotoxic amyloid beta and pathogenesis of Alzheimer\u2019s disease and brain damage after traumatic brain injury. We will further analyse the role of lymphangiogenic growth factors and lymphatic vessels in brain solute clearance, immune cell trafficking and in a mouse model of multiple sclerosis. The meningeal lymphatics could be involved in a number of neurodegenerative and neuroinflammatory diseases of considerable human and socioeconomic burden. Several of our previous concepts have already been translated to clinical development and we aim to develop proof-of-principle therapeutic concepts in this project. I feel that we are just now in a unique position to advance frontline European translational biomedical research in this suddenly emerging field, which has received great attention worldwide.", "To": ["2022-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["743155"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 149 921"], "Project_Title": ["BOTFIND: Finding Bots, Detect Harassing Automation, and Restoring Trust in Social Media Civic Engagement"], "Total_Cost": ["EUR 149 921"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["BOTFIND"], "Technology_Description": "Social media platforms have become tools for manipulating public opinion during elections. In particular, \u201cbots\u201d are algorithms that automate rapid, widespread interactions with citizens, often with deleterious effects on public knowledge of science, social inequality, and public policy options. Through the ERC COMPROP Consolidator award, researchers have demonstrated that even simple bots (i) effectively keep negative messages and fake news in circulation longer (ii) target journalists and civil society groups and (iii) operate with little oversight from social media firms. Such algorithms have negative consequences both for public trust in technology innovation and for the quality of public deliberation in Europe\u2019s democracies. ERC researchers have been able to identify highly automated, politically-manipulative social media accounts post hoc. This project will allow researchers to take what we have learned and produce an online tool that allows people to evaluate suspicious social media accounts. Most social media platforms are slow to address troll and bot activity, so this innovative tool will put ERC research into public service in Europe\u2014and around the world.", "To": ["2019-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["767454"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["THE UNIVERSITY OF EXETER"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Perceptual Learning"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["Perceptual Learning"], "Technology_Description": "Perceptual learning is fundamental to human cognition. It can be defined as an enhancement in the ability to distinguish between similar stimuli (that otherwise would be very hard to tell apart) as a consequence of experience with them, or with stimuli similar to the target stimuli. This allows the wine connoisseur to distinguish between different wines, the bird watcher to tell one warbler from another, and people to identify that face as a given person rather than someone else, if the face is taken from an ethnic grouping that they are familiar with. My research focuses on the mechanisms responsible for perceptual learning. By using a range of neuroscience techniques (tDCS, fMRI, TMS/MEP, EEG/ERP) in conjunction with the behavioural designs provided by experimental psychology I will investigate the neural basis for perceptual learning, test a computational model of the phenomenon, and try to control the development and expression of this perceptual skill. This programme of research will train me in new techniques, further develop my expertise in the domain of perceptual learning, and allow me to work in one of the leading laboratories for this type of research at the present time. It will also allow me to raise my and my discipline's profile, and to do this, as part of this research proposal, I will convene an International Workshop on Perceptual Learning to bring together the various researchers working on this issue and publish the proceedings as an edited book.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["743702"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA", "ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA"], "EU_Contribution": ["EUR 1 997 000"], "Project_Title": ["Alchemy in the Making: From ancient Babylonia via Graeco-Roman Egypt into the Byzantine, Syriac and Arabic traditions (1500 BCE - 1000 AD)"], "Total_Cost": ["EUR 1 997 000"], "Country": ["Italy", "Italy"], "Project_ACR": ["AlchemEast"], "Technology_Description": "The AlchemEast project is devoted to the study of alchemical theory and practice as it appeared and developed in distinct, albeit contiguous (both chronologically and geographically) areas: Graeco-Roman Egypt, Byzantium, and the Near East, from Ancient Babylonian times to the early Islamic Period. This project combines innovative textual investigations with experimental replications of ancient alchemical procedures. It uses sets of historically and philologically informed laboratory replications in order to reconstruct the actual practice of ancient alchemists, and it studies the texts and literary forms in which this practice was conceptualized and transmitted. It proposes new models for textual criticism in order to capture the fluidity of the transmission of ancient alchemical writings. AlchemEast is designed to carry out a comparative investigation of cuneiform tablets as well as a vast corpus of Greek, Syriac and Arabic writings. It will overcome the old, pejorative paradigm that dismissed ancient alchemy as a \"pseudo-science\", by proposing a new theoretical framework for comprehending the entirety of ancient alchemical practices and theories. Alongside established forms of scholarly output, such as critical editions of key texts, AlchemEast will provide an integrative, longue dur\u00e9e perspective on the many different phases of ancient alchemy. It will thus offer a radically new vision of this discipline as a dynamic and diversified art that developed across different technical and scholastic traditions. This new representation will allow us to connect ancient alchemy with medieval and early modern alchemy and thus fully reintegrate ancient alchemy in the history of pre-modern alchemy as well as in the history of ancient science more broadly.", "To": ["2022-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["724914"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITAT DE VALENCIA", "UNIVERSITAT DE VALENCIA"], "EU_Contribution": ["EUR 1 969 821"], "Project_Title": ["Collective Infectious Units and the Social Evolution of Viruses"], "Total_Cost": ["EUR 1 969 821"], "Country": ["Spain", "Spain"], "Project_ACR": ["Vis-a-Vis"], "Technology_Description": "A widely accepted view in virology is that virions function as independent infectious units. However, recent work by us and others indicates that viruses are often transmitted as more complex structures, such as virion aggregates, lipid vesicles or protein matrices harbouring multiple infectious particles. This demonstrates that viruses can be transmitted as \u201ccollective infectious units\u201d, in sharp contrast with the current paradigm. Critically, these recent discoveries now set the stage for the evolution of social interactions, a previously unappreciated facet of viruses. I propose to investigate how collective infectious units drive virus social evolution using state-of-the-art tools from the fields of virology, genetics, structural biology, and nanotechnology. The effects of collective infectivity on viral fitness will be tested directly using experimental evolution and genetic engineering, and confirmed in vivo. Three widely different viruses will be used to achieve generality: human enteroviruses, a vector-borne rhabdovirus, and a baculovirus. Furthermore, the implications of virus social interactions for the maintenance of genetic diversity, evolvability, virulence evolution, and the emergence of drug resistance will be investigated. Radically new processes such as the putative extracellular fusion of viral particles will be also explored. I expect that infectious units constituted by viruses from different species will be uncovered as well, with far-reaching implications for epidemiology. It is becoming increasingly recognized that parasite sociality is a disease determinant, and our results may therefore inspire new antiviral strategies. In sum, this project aims at laying the foundations of virus sociality from a mechanistically-informed, bottom-up approach. Importantly, beyond their practical importance viruses will also provide a simple and tractable system that will help us to establish more general principles of social evolution.", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["724519"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITAT DE VALENCIA", "UNIVERSITAT DE VALENCIA"], "EU_Contribution": ["EUR 1 998 750"], "Project_Title": ["Smart Coordination Polymers with Compartmentalized Pockets for Adaptive Guest Entrance"], "Total_Cost": ["EUR 1 998 750"], "Country": ["Spain", "Spain"], "Project_ACR": ["S-CAGE"], "Technology_Description": "The S-CAGE project aims to develop a new generation of crystalline solids with periodically-organized discrete voids, or compartments, that would benefit from the combination of the high stability and robustness of dense materials with the structural diversity and versatility (and therefore large applicability) of open frameworks. These coordination polymers (CPs) will be capable of interacting with guest species in the absence of large channels or permanent pores due to the presence of dynamic entrances. This could open new horizons towards the design of unprecedented materials as an enhanced interplay between the guests and the frameworks will be achieved resulting from the confined space of the compartmentalized pockets.", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["724681"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE", "LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE"], "EU_Contribution": ["EUR 1 483 992"], "Project_Title": ["Justice, Morality, and the State in Amazonia"], "Total_Cost": ["EUR 1 483 992"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["JUSTAM"], "Technology_Description": "The project will investigate the social, cultural and cognitive bases of justice, or the morally correct assignment of goods and evils, with a focus on the indigenous peoples of Western Amazonia. It will develop an analysis of issues ranging from emotions, fairness, entitlement and equality in contexts of resource distribution, to punishment, vengeance, and attributions of responsibility. This will enlarge our understanding of how and why patterns of moral judgement vary across cultures, with particular attention paid to the role played by cultural constructions of personhood. The current situation of rapid social change in Amazonia, driven largely by the increased presence of the state in everyday life, provides a unique opportunity for assessing how morality and ethics are shaped by social conditions such as the size of networks of cooperation, processes for generating consensus, and the management of conflicts and disputes. This will be used to address longstanding questions concerning the evolution of morality, including how fairness is linked to cooperation within ever larger groups. The innovative methodology, combining ethnography with experiments and games adapted from psychology, economics, and experimental philosophy, will allow for a vastly more comprehensive set of data on justice in action than has previously been achieved. This will permit the elaboration of a sophisticated and distinctively Amazonian theory of justice, grounded in emotional responsiveness to others and respect for personal autonomy, that is capable of entering into critical dialogue with mainstream Western theories and understandings, while also challenging a number of dominant stereotypes of small-scale, non-state societies. The results will further be used to formulate a general framework for development projects and policy interventions with indigenous peoples, which could drastically improve their success rate and potentially be adapted for use in a range of global contexts.", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["715725"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["CARDIFF AND VALE UNIVERSITY HEALTH BOARD", "UNIVERSITAT DE BARCELONA", "HOSPITAL CLINIC I PROVINCIAL DE BARCELONA", "CARDIFF UNIVERSITY"], "EU_Contribution": ["EUR 274 500"], "Project_Title": ["International impact of TALK\u00a9: a simple and practical approach to multi-professional structured feedback and debriefing, to be used after unplanned learning events in clinical environments."], "Total_Cost": ["EUR 274 500"], "Country": ["United Kingdom", "Spain", "Spain", "United Kingdom"], "Project_ACR": ["TALK"], "Technology_Description": "TALK\u00a9 is a communication tool which aims to guide multi-professional clinical teams learning and improving quality of patient care and patient safety together. It is a simple and practical approach to multi-professional structured feedback and debriefing, to be used after unplanned learning events in clinical environments. ", "To": ["2020-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["United Kingdom"], "Activity": ["Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["734753"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG", "UNIVERSITAT DE VALENCIA", "ISTITUTO NAZIONALE DI FISICA NUCLEARE", "\"NATIONAL CENTER FOR SCIENTIFIC RESEARCH \"\"DEMOKRITOS\"\"\""], "EU_Contribution": ["EUR 3 795 000"], "Project_Title": ["Astroparticle and Oscillations Research with Cosmics in the Abyss (ARCA and ORCA)"], "Total_Cost": ["EUR 3 795 000"], "Country": ["Netherlands", "France", "Germany", "Spain", "Italy", "Greece"], "Project_ACR": ["KM3NeT 2.0"], "Technology_Description": "KM3NeT is a large Research Infrastructure that will consist of a network of deep-sea neutrino telescopes in the Mediterranean Sea with user ports for earth and sea sciences. The main science objectives, a description of the technology and a summary of the costs are presented in the KM3NeT 2.0 Letter of Intent. Following the appearance of KM3NeT 2.0 on the ESFRI roadmap 2016 and in line with the recommendations of the Assessment Expert Group in 2013, this proposal addresses the Coordination and Support Actions (CSA) to prepare a legal entity for KM3NeT, thereby providing a sustainable solution for the operation of the Research Infrastructure during ten (or more) years. During the EU-funded Design Study (2006 - 2010) and Preparatory Phase (2008-2012), a cost-effective technology was developed, deep-sea sites were selected and the Collaboration was formed. This proposal constitutes a second Preparatory Phase. The project will be carried out within the context of the current KM3NeT Collaboration which already has a provisional implementation of the management and governance of the Research Infrastructure in place. The resources requested will be complemented by the Collaboration.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["INFRADEV-02-2016 - Preparatory Phase and support to early phase of ESFRI projects"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Netherlands"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations"], "From": ["2017-01-01"], "Project_ID": ["739560"], "Call_for_Proposal": ["H2020-INFRADEV-2016-2"]}, -{"Partners": ["LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE", "LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE"], "EU_Contribution": ["EUR 1 497 505"], "Project_Title": ["The Design of Social Policy in a Heterogeneous World"], "Total_Cost": ["EUR 1 497 505"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["HETEROPOLIS"], "Technology_Description": "Modern societies are characterized by tremendous heterogeneity in economic outcomes: from heterogeneity in wages and employment, to heterogeneity in capital income, wealth and health outcomes. It is unclear, however, how to map heterogeneity in these outcomes to heterogeneity in welfare. This mapping is crucial for the design of tax and benefit systems, providing insurance against individual risk and redistributing income between individuals, while maintaining proper incentives.", "To": ["2022-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-02-01"], "Project_ID": ["716485"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["SIMULA RESEARCH LABORATORY AS", "SIMULA RESEARCH LABORATORY AS"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Mathematical and computational foundations for modeling cerebral fluid flow."], "Total_Cost": ["EUR 1 500 000"], "Country": ["Norway", "Norway"], "Project_ACR": ["Waterscales"], "Technology_Description": "Your brain has its own waterscape: whether you are reading or sleeping, fluid flows through the brain tissue and clears waste in the process. These physiological processes are crucial for the well-being of the brain. In spite of their importance we understand them but little. Mathematics and numerics could play a crucial role in gaining new insight. Indeed, medical doctors express an urgent need for multiscale modeling of water transport through the brain, to overcome limitations in traditional techniques. Surprisingly little attention has been paid to the numerics of the brain's waterscape however, and fundamental knowledge is missing.", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Norway"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-04-01"], "Project_ID": ["714892"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE", "LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE"], "EU_Contribution": ["EUR 1 489 518"], "Project_Title": ["Addressing Too Big to Fail: Resolution, Organizational Structure, and Funding of Global Banks"], "Total_Cost": ["EUR 1 489 518"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["TBTF"], "Technology_Description": "One of the main unresolved challenges of the recent financial crisis is how society should deal with global banks that are \u201ctoo big to fail.\u201d The collapse of Lehman Brothers vividly demonstrated the costs of the failure of such an institution, with sweeping repercussions for the financial system and the broader economy. Yet, implicit public guarantees that would prevent such failures are equally costly, creating moral hazard in the form of increased risk taking and incentives for financial institutions to become larger and more complex.", "To": ["2021-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-12-01"], "Project_ID": ["715467"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["UNIVERSITAT DE BARCELONA", "UNIVERSITAT DE BARCELONA"], "EU_Contribution": ["EUR 149 962"], "Project_Title": ["Making Complex Gas Analytics Friendly and Available ASAP"], "Total_Cost": ["EUR 149 962,50"], "Country": ["Spain", "Spain"], "Project_ACR": ["GasApp"], "Technology_Description": "GasApp aims at bringing the capability to detect gases to every existing smartphone in just a few months. Carrying out a gas measurement will be as simple as taking a snapshot with the phone\u2019s camera. Technically, we will rely on colorimetry methods to turn the presence of chemical substances into colour changes. GasApp wants to take a fast track towards accurate, highly specific, and highly accessible measurements by rethinking the concept of \u201cubiquitous sensing\u201d. Instead of developing new complex electronic devices, our approach builds upon existing ubiquitous devices (i.e. smartphones), a new software App and inexpensive Tags based on knowledge produced in an ERC-funded project to achieve a user friendly gas-sensing product ASAP, and making business out of this opportunity. ", "To": ["2018-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["727297"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU GEOLOGIE SI GEOECOLOGIE MARINA-GEOECOMAR", "INSTITUTUL NATIONAL DE CERCERTARE DEZVOLTARE PENTRU STIINTE BIOLOGICE RA", "Unitatea Executiva pentru Finantarea Invatamantului Superior, a Cercetarii, Dezvoltarii si Inovarii", "Agentia de Administrare a Retelei Nationale de Informatica Pentru Educatie si Cercetare", "WasserCluster Lunz - Biologische Station GmbH", "BULGARIAN ACADEMY OF SCIENCES", "USTAV VYZKUMU GLOBALNI ZMENY AV CR VVI", "EUROPPORTUNITIES OU", "UNIVERSITE DE LORRAINE", "Bundesanstalt fuer Gewaesserkunde", "HELMHOLTZ-ZENTRUM GEESTHACHT ZENTRUM FUR MATERIAL- UND KUSTENFORSCHUNG GMBH", "HELLENIC CENTRE FOR MARINE RESEARCH", "SZECHENYI ISTVAN UNIVERSITY", "UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK", "CONSIGLIO NAZIONALE DELLE RICERCHE", "CORILA - CONSORZIO PER IL COORDINAMENTO DELLE RICERCHE INERENTI AL SISTEMA LAGUNARE DI VENEZIA", "INTEGRATED CARBON OBSERVATION SYSTEM EUROPEAN RESEARCH INFRASTRUCTURE CONSORTIUM", "EUROPEAN MULTIDISCIPLINARY SEAFLOORAND WATER COLUMN OBSERVATORY - EUROPEAN RESEARCH INFRASTRUCTURE CONSORTIUM (EMSO ERIC)", "INSTITUTUL DE CHIMIE ACADEMIA DE STIINTE A MOLDOVEI", "STICHTING DELTARES", "UNIVERSITAT POLITECNICA DE CATALUNYA", "AUTORIDAD PORTUARIA DE SEVILLA", "STICHTING IHE DELFT", "THE UNIVERSITY OF STIRLING", "THE UNIVERSITY OF BIRMINGHAM", "NATURAL ENVIRONMENT RESEARCH COUNCIL", "PLYMOUTH MARINE LABORATORY", "Odessa State Environmental University", "DEMOCRITUS UNIVERSITY OF THRACE"], "EU_Contribution": ["EUR 3 996 405"], "Project_Title": ["PREPARATORY PHASE FOR THE PAN-EUROPEAN RESEARCH INFRASTRUCTURE DANUBIUS\u2013RI \u201cTHE INTERNATIONAL CENTRE FOR ADVANCED STUDIES ON RIVER-SEA SYSTEMS"], "Total_Cost": ["EUR 3 996 405"], "Country": ["Romania", "Romania", "Romania", "Romania", "Austria", "Bulgaria", "Czech Republic", "Estonia", "France", "Germany", "Germany", "Greece", "Hungary", "Ireland", "Italy", "Italy", "Finland", "Italy", "Moldova", "Netherlands", "Spain", "Spain", "Netherlands", "United Kingdom", "United Kingdom", "United Kingdom", "United Kingdom", "Ukraine", "Greece"], "Project_ACR": ["DANUBIUS-PP"], "Technology_Description": "DANUBIUS-PP is a three-year project to raise DANUBIUS-RI (International Centre for Advanced Studies on River-Sea Systems) to the legal, financial and technical maturity required for successful implementation and development. DANUBIUS-RI is a pan-European distributed research infrastructure (RI) building on existing expertise to support interdisciplinary research on river-sea (RS) systems, spanning the environmental, social and economic sciences. It will provide access to a range of RS systems, facilities and expertise, a \u2018one-stop shop\u2019 for knowledge exchange, access to harmonised data, and a platform for interdisciplinary research, education and training.", "To": ["2019-11-30, ongoing project"], "Meta": [""], "Topic_s": ["INFRADEV-02-2016 - Preparatory Phase and support to early phase of ESFRI projects"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Romania"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Other", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-12-01"], "Project_ID": ["739562"], "Call_for_Proposal": ["H2020-INFRADEV-2016-2"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN", "OROBOROS INSTRUMENTS GmbH", "UNIVERSITAT DE VALENCIA", "UNIVERSITA' DEGLI STUDI DI SIENA", "THE QUEEN'S UNIVERSITY OF BELFAST"], "EU_Contribution": ["EUR 2 877 076,80"], "Project_Title": ["Training in Cancer Mechanisms and Therapeutics"], "Total_Cost": ["EUR 2 877 076,80"], "Country": ["Ireland", "Austria", "Spain", "Italy", "United Kingdom"], "Project_ACR": ["TRACT"], "Technology_Description": "The European community requires early stage researchers (ESRs) trained in next-generation technologies for improved detection and treatment of oral and oesophageal cancers. The number of oral cancers diagnosed in the EU has increased by over 75% in the last 30 years, with long-term survival rates of only 50%. This is typically due to the late diagnosis of the disease and resistance to current therapies. Through the collaborative expertise of clinicians, biochemists, immunologists, and chemists TRACT will enable ESRs to discover novel insights into the molecular and cellular basis of these cancers and generate new diagnostic tools and therapeutics that improve patient response and survival. Each Institution brings unique but complementary expertise in cancer metabolism, metabolomics, high-resolution imaging, biomarker identification, computational modelling, medicinal chemistry, target validation, drug development and translational medicine. Industrial placements in five European countries will ensure ESRs receive specialised training in the development of next-generation technologies in such areas as whole genome sequencing, CRISPR technology, drug screening, exosome isolation and analysis, cancer imaging, metabolism and metabolite analysis in addition to the unique employment experience of working in the private sector. Courses in commercialisation, project management and presentation skills will ensure ESRs will have the ability to present their results to the entire cross-section of the European community, through public engagement. TRACT will deliver a cohort of internationally mobile cancer researchers with interdisciplinary skills who will have enhanced career prospects and be in a position to have an impact on the European and global research stage by providing new technologies that can drive entrepreneurship into the European economy and improved diagnostics and treatment options for cancer patients in Europe and beyond.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["721906"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["KING'S COLLEGE LONDON", "KING'S COLLEGE LONDON", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 499 095"], "Project_Title": ["Authority and Innovation in Early Franciscan Thought (c. 1220-56)"], "Total_Cost": ["EUR 1 499 095"], "Country": ["United Kingdom", "United Kingdom", "France"], "Project_ACR": ["INNOVATION"], "Technology_Description": "INNOVATION anticipates a breakthrough in scholarly understanding of the medieval origins of modern Western philosophy. This breakthrough will be achieved by exposing the pioneering nature of early thirteenth-century Franciscan thought and its pivotal significance for the subsequent formation of the Western philosophical identity. The work of early Franciscans has largely been neglected in scholarly circles, on the assumption that they merely codified the work of past authorities, where later Franciscans developed innovative ideas that laid the foundation for the development of modern philosophy. INNOVATION will contest this assumption by producing the first comprehensive study of the sources, method, content, and later medieval reception of early Franciscan thought. In conducting this study, I will implement a groundbreaking method of reading scholastic texts, which is attentive to the way that practice informed theory in the high Middle Ages. This \u2018practice-led\u2019 hermeneutic will provide a resource for re-envisaging the entire state of the art in the study of scholasticism. As regards early Franciscans, it will allow me to identify novelty, often due to the use of Islamic sources, where past scholars have perceived unoriginality. On this basis, I will highlight previously unnoticed connections between the early and late Franciscan schools. By these means, I will illustrate how Western thought has been nourished by the ethos of a particular religious order and by Islamic thought, pointing up a shared Muslim-Western philosophical identity that is often overlooked but urgently needed to overcome severe fractures in today\u2019s society. At the same time, I will emphasize that Franciscan ideas only became modern once removed from their practice-led context. In juxtaposing the cultural paradigms of philosophy and religious practice, consequently, I will advance knowledge by producing the first nuanced scholarly account of the Franciscan origins of modern Western thought.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2017-01-01"], "Project_ID": ["714427"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["DUNDALK INSTITUTE OF TECHNOLOGY", "Institut Catal\u00e0 de Recerca de l'Aigua, Fundaci\u00f3 Privada", "EESTI MAAULIKOOL", "FORSCHUNGSVERBUND BERLIN EV", "KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW", "UNIVERSITAT DE BARCELONA", "UNIVERSITE DE GENEVE", "UPPSALA UNIVERSITET"], "EU_Contribution": ["EUR 3 056 654,16"], "Project_Title": ["Management of Climatic Extreme Events in Lakes Reservoirs for the Protection of Ecosystem Services"], "Total_Cost": ["EUR 3 056 654,16"], "Country": ["Ireland", "Spain", "Estonia", "Germany", "Netherlands", "Spain", "Switzerland", "Sweden"], "Project_ACR": ["MANTEL"], "Technology_Description": "Environmental perturbations to lakes and reservoirs occur largely as episodic climatic events. These range from relatively short mixing events to storms and heat waves. While the driving events occur along a continuum of frequency and magnitude, however, their effect is generally longer lasting than the events themselves. In addition, the more extreme weather events are now becoming increasingly frequent, a trend that has been linked to directional climate change and is projected to continue in the coming decades. Understanding the impact of these short-lived pressures requires monitoring that captures the event (hours\u2013days) and the ensuing impact, that can last for months or even years. Only recently has automated high frequency monitoring (HFM) of lakes been adopted throughout Europe. This Training Network will investigate the effects of the most extreme events, and of cumulative lower magnitude events, using HFM, while at the same time training a cohort of doctoral students in state-of-the art technology, data analysis and modelling. The aim of the EJD is to change the way in which water quality monitoring is carried out so that the effects of episodic climatic events can be understood, thus ensuring that future water management strategies can explicitly account for their effects.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EJD - European Joint Doctorates"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["722518"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["UNIVERSITAT DE VALENCIA", "UNIVERSITAT DE VALENCIA"], "EU_Contribution": ["EUR 1 527 351,26"], "Project_Title": ["Chemical Engineering of Functional Stable Metal-Organic Frameworks: Porous Crystals and Thin Film Devices"], "Total_Cost": ["EUR 1 527 351,26"], "Country": ["Spain", "Spain"], "Project_ACR": ["chem-fs-MOF"], "Technology_Description": "Metal-Organic-Frameworks (MOFs) offer appealing advantages over classical solids from combination of high surface areas with the crystallinity of inorganic materials and the synthetic versatility (unlimited combination of metals and linkers for fine tuning of properties) and processability of organic materials. Provided chemical stability, I expect combination of porosity with manipulable electrical and optical properties to open a new world of possibilities, with MOFs playing an emerging role in fields of key environmental value like photovoltaics, photocatalysis or electrocatalysis. The conventional insulating character of MOFs and their poor chemical stability (only a minimum fraction are hydrolytically stable) are arguably the two key limitations hindering further development in this context.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["714122"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["CONSIGLIO NAZIONALE DELLE RICERCHE", "STAZIONE ZOOLOGICA ANTON DOHRN", "UNIVERSITETET I TROMSOE", "THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN", "HELMHOLTZ ZENTRUM FUR OZEANFORSCHUNG KIEL", "KATHOLIEKE UNIVERSITEIT LEUVEN", "UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK", "ECOAST", "FUNDACION CENTRO DE EXCELENCIA EN INVESTIGACION DE MEDICAMENTOS INNOVADORES EN ANDALUCIA", "MICRODISH BV", "CONSORZIO ITALBIOTEC"], "EU_Contribution": ["EUR 2 853 005,40"], "Project_Title": ["Improving the flow in the pipeline of the next generation of marine biodiscovery scientists"], "Total_Cost": ["EUR 2 853 005,40"], "Country": ["Italy", "Italy", "Norway", "United Kingdom", "Germany", "Belgium", "Ireland", "Belgium", "Spain", "Netherlands", "Italy"], "Project_ACR": ["MarPipe"], "Technology_Description": "MarPipe is a consortium of 11 partners (IBP-CNR, SZN, UiT, UNIABDN, GEOMAR, KULeuven, UCC, eCOAST, MEDINA, MicroDish, Italbiotec) based in 8 countries (I, N, UK, D, B, IRL, E, NL), including 3 from the non-academic sector. We will train 11 ESRs in marine drug-discovery, providing these researchers with unique skills toward becoming world leaders in this research field and to advance their careers in academia or industry. MarPipe PhDs will be trained in a programme including training-by-research, joint courses of technical, scientific and transferrable skills, active participation to public scientific events, and an intense inter-sectoral networking exchange plan. ", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations"], "From": ["2016-11-01"], "Project_ID": ["721421"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK", "UNIVERSITY OF STRATHCLYDE", "INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER", "WAVEC/OFFSHORE RENEWABLES - CENTRO DE ENERGIA OFFSHORE ASSOCIACAO", "CONSORCIO PARA EL DISENO, CONSTRUCCION, EQUIPAMIENTO Y EXPLOTACION DE LA PLATAFORMA OCEANICA DE CANARIAS", "SINTEF ENERGI AS", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.", "CONSIGLIO NAZIONALE DELLE RICERCHE", "UNIVERSITEIT GENT", "STICHTING MARITIEM RESEARCH INSTITUUT NEDERLAND", "UPPSALA UNIVERSITET", "AALBORG UNIVERSITET", "BIRD & BIRD LLP"], "EU_Contribution": ["EUR 1 999 798,75"], "Project_Title": ["Marine Renewable Energy Research Infrastructure"], "Total_Cost": ["EUR 1 999 798,75"], "Country": ["Ireland", "United Kingdom", "France", "Portugal", "Spain", "Norway", "Germany", "Italy", "Belgium", "Netherlands", "Sweden", "Denmark", "United Kingdom"], "Project_ACR": ["MARINERGI"], "Technology_Description": "The objective of MARINERG-i is to become the leading internationally distributed infrastructure in the Marine Renewable Energy (MRE) sector. Its integrated nature and co-ordinated approach will accelerate the research development and deployment of offshore wind, wave, tidal and combined energy technologies and help maintain Europe as a global leader in this industry. In addition MARINERG-i will strengthen European, scientific and engineering excellence and expertise as it\u2019s combined facilities represent an indispensable tool to foster innovation across a large variety of MRE technologies and systems and through all key stages of technology development (TRL\u2019s 1-9). ", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["INFRADEV-02-2016 - Preparatory Phase and support to early phase of ESFRI projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["739550"], "Call_for_Proposal": ["H2020-INFRADEV-2016-2"]}, -{"Partners": ["LEIBNIZ-INSTITUT FUR RAUMBEZOGENE SOZIALFORSCHUNG (IRS) EV", "UNIWERSYTET IM. ADAMA MICKIEWICZA W POZNANIU", "ROSKILDE UNIVERSITET", "UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK", "BALLYHOURA DEVELOPMENT LTD", "LEIBNIZ-INSTITUT FUR LANDERKUNDE EV", "University of the Aegean-Research Unit", "OTELO EGEN", "INSTITUTO UNIVERSITARIO DE LISBOA"], "EU_Contribution": ["EUR 2 529 895,32"], "Project_Title": ["Social Enterpreneurship in Structurally Weak Rural Regions: Analysing Innovative Troubleshooters in Action"], "Total_Cost": ["EUR 2 529 895,32"], "Country": ["Germany", "Poland", "Denmark", "Ireland", "Ireland", "Germany", "Greece", "Austria", "Portugal"], "Project_ACR": ["RURACTION"], "Technology_Description": "Structurally weak rural regions are faced with major social and economic problems. In comparison to urban or intermediate regions, predominantly rural regions are economically less productive and they provide a less extensive scope of desired goods and services. As a consequence, the regions experience a loss of inhabitants, especially of young and highly skilled people. Thus, downward spirals are set in motion that further reduce economic opportunities and prevent rural regions from overcoming their structural deficits. ", "To": ["2020-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2016-12-01"], "Project_ID": ["721999"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["KATHOLIEKE UNIVERSITEIT LEUVEN"], "EU_Contribution": ["EUR 160 800"], "Project_Title": ["Probing local ROS distributions in Calcium signaling microdomains after myocardial infarction"], "Total_Cost": ["EUR 160 800"], "Country": ["Belgium"], "Project_ACR": ["MICROS"], "Technology_Description": "An increasing number of people suffer cardiovascular diseases and experience myocardial infarction (MI). The subsequent heart remodeling is characterized by weaker contractility, hypertrophy and lethal arrhythmias. The poorly-understood underlying mechanism is related to calcium (Ca2+) mishandling in cardiomyocytes and oxidative stress. To date, most of the studies described global cellular processes and were unable to propose efficient therapies. ", "To": ["2019-07-17, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-18"], "Project_ID": ["752824"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["LUNDS UNIVERSITET", "LUNDS UNIVERSITET"], "EU_Contribution": ["EUR 1 990 895"], "Project_Title": ["Collider Phenomenology and Event Generators"], "Total_Cost": ["EUR 1 990 895"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["MorePheno"], "Technology_Description": "Collider physics is about exploring the smallest constituents of matter, and unravelling the basic laws of the Universe. Unfortunately there can be a huge gap between a one-line formula of a fundamental theory and the experimental reality it implies. Phenomenology is intended to fill that gap, e.g. to explore the consequences of a theory such that it can be directly compared with data. ", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-11-01"], "Project_ID": ["668679"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["THE UNIVERSITY OF EDINBURGH", "THE UNIVERSITY OF EDINBURGH"], "EU_Contribution": ["EUR 2 456 120"], "Project_Title": ["f-block hydrocarbon interactions: exploration; exploitation"], "Total_Cost": ["EUR 2 456 120"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["f-ex"], "Technology_Description": "Understanding, controlling, and predicting the subtle interactions that hydrocarbons form with metals is a major challenge in molecular science, and a key technology enabler in areas such as homogeneous catalysis, drug recognition, polymer properties, and metal recovery. For the f-block, it is important due to the urgent need for clean access to critical elements such as neodymium, and the safe handling of nuclear waste. However, technical challenges of paramagnetism, radiotoxicity, and relativistic effects, make quantifying and exploiting f-block hydrocarbon interactions very hard using traditional methods or calculations alone. ", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["740311"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET", "IFOM FONDAZIONE ISTITUTO FIRC DI ONCOLOGIA MOLECOLARE", "PANEPISTIMIO PATRON", "KAROLINSKA INSTITUTET", "KRAEFTENS BEKAEMPELSE", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "UNIVERSITE DE GENEVE", "STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS", "ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON", "KANCERA AB"], "EU_Contribution": ["EUR 3 990 269,16"], "Project_Title": ["Targeting SYNthetic lethal interactions for new cancer treatments TRAINing network"], "Total_Cost": ["EUR 3 990 269,16"], "Country": ["Denmark", "Italy", "Greece", "Sweden", "Denmark", "United Kingdom", "Switzerland", "Netherlands", "Greece", "Sweden"], "Project_ACR": ["SYNTRAIN"], "Technology_Description": "Breast and ovarian cancer constitute serious health challenges in the EU. To identify new improved cancer therapeutic approaches, we will pursue a multi-facetted synthetic lethal approach, which takes advantage of the inherent genetic instability of cancer cells. Most mutations acquired by cancer cells do not cause lethality, but the very same mutations may cause cell death when a second gene in a redundant pathway is inactivated. Thus, targeting a gene that is synthetic lethal together with a cancer-specific mutation will kill only cancer cells while sparing normal cells. Synthetic lethal approaches have been clinically pioneered by members of our consortium, by combining cancer-promoting mutations (e.g. in BRCA2) with inactivating combinations of DNA repair genes. We will use this approach as the scientific frame for our ETN (SYNTRAIN) consisting of 9 academic and 1 SME beneficiary as well as 3 partners. We aim to identify synthetic lethal interactions and exploit them to innovate future breast and ovarian cancer treatments through compound screening and development. SYNTRAIN consists of World leading researchers with complementary knowledge in genome maintenance and stress response pathways, and a critical mass of expertise for providing an excellent training in screening methodologies, mechanistic investigations, and drug discovery. We will offer a structured training program that exceeds the capacities of each individual member. We will educate a future generation of cancer researchers with a high innovative capacity and skills that enhances their career prospects in both academia and industry. Our aims are to train young researchers: i) in techniques preparing for a career in cancer research, ii) in complementary skills relevant for work in academia and the pharma industry and iii) to become creative and entrepreneurial, capable of bridging the gap between basic and applied research.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-09-01"], "Project_ID": ["722729"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["ECRIN EUROPEAN CLINICAL RESEARCH INFRASTRUCTURE NETWORK", "THE UNIVERSITY OF LIVERPOOL", "CONSORZIO PER VALUTAZIONI BIOLOGICHE E FARMACOLOGICHE", "STICHTING KATHOLIEKE UNIVERSITEIT", "INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE", "HELSINGIN JA UUDENMAAN SAIRAANHOITOPIIRIN KUNTAYHTYM\u00c4", "FUNDACIO SANT JOAN DE DEU", "SWISS CLINICAL TRIAL ORGANISATION VEREIN", "KAROLINSKA INSTITUTET", "HELSE BERGEN HF*HAUKELAND UNIVERSITY HOSPITAL", "TARTU ULIKOOL", "ARISTOTELIO PANEPISTIMIO THESSALONIKIS", "OKIDS GMBH", "THE NATIONAL CHILDREN'S RESEARCH CENTRE", "VERENIGING SAMENWERKENDE OUDER- EN PATIENTENORGANISATIES"], "EU_Contribution": ["EUR 3 296 000"], "Project_Title": ["Paediatric Clinical Research Infrastructure Network"], "Total_Cost": ["EUR 3 296 000"], "Country": ["France", "United Kingdom", "Italy", "Netherlands", "France", "Finland", "Spain", "Switzerland", "Sweden", "Norway", "Estonia", "Greece", "Austria", "Ireland", "Netherlands"], "Project_ACR": ["PedCRIN"], "Technology_Description": "Children\u2019s health is a major societal challenge for Europe and the world, requiring development of paediatric medicines and treatments strategies based on evidence derived from clinical trials demonstrating efficacy and safety in infants and children, rather than on uncritical extrapolation from adult data (over 50 % of the medicines used for children had not been tested in this specific age group).", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["INFRADEV-03-2016-2017 - Individual support to ESFRI and other world-class research infrastructures"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["France"], "Activity": ["Other", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Other", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other", "Other", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["731046"], "Call_for_Proposal": ["H2020-INFRADEV-2016-1"]}, -{"Partners": ["ARISTOTELIO PANEPISTIMIO THESSALONIKIS", "ECOLE NATIONALE SUPERIEURE DES MINES DE PARIS", "FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG", "UNIVERSITAET FUER BODENKULTUR WIEN", "POLITECNICO DI TORINO", "UPPSALA UNIVERSITET", "ASTON UNIVERSITY", "ADVANCED TECHNOLOGY PARTNERS SRL", "THE UNIVERSITY OF SHEFFIELD", "OSSDSIGN AB", "ESTIA CONSULTING & ENGINEERING S.A.", "BEIJING UNIVERSITY OF CIVIL ENGINEERING AND ARCHITECTURE", "FEDERAL STATE BUDGETARY EDUCATIONAL INSTITUTION OF HIGHER EDUCATION NOSOV MAGNITOGORSK STATE TECHNICAL UNIVERSITY", "Shanghai University", "FEDERAL STATE-FUNDED EDUCATION INSTITUTION OF HIGHER PROFESSIONAL EDUCATION PERM NATIONAL RESEARCH POLYTECHNIC UNIVERSITY", "Arizona Board of Regents", "Michigan Technological University", "SAINT PETERSBURG NATIONAL RESEARCH UNIVERSITY OF INFORMATION TECHNOLOGIES, MECHANICS AND OPTICS", "University of Florida"], "EU_Contribution": ["EUR 900 000"], "Project_Title": ["Fracture Across Scales and Materials, Processes and Disciplines"], "Total_Cost": ["EUR 1 125 000"], "Country": ["Greece", "France", "Germany", "Austria", "Italy", "Sweden", "United Kingdom", "Italy", "United Kingdom", "Sweden", "Greece", "China", "Russia", "China", "Russia", "United States", "United States", "Russia", "United States"], "Project_ACR": ["FRAMED"], "Technology_Description": "Fracture of materials is problematic across many disciplines and scales, from large building collapses and costly preventative engineering fixes to the personal injuries caused by bone fracture. 80\u201390% of all structural failures occur as a result of fatigue and thus fracture mechanisms. Extensive testing of materials for fracture parameters before use in specific applications can be costly, wasteful and prohibitive when creating large structures. Computer models can be used to assess the probability and impact of fracture for a specific application and material, thus serving as a prediction tool. However, the models used are not accurate and reliable across multiple scales and across varying applications. ", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Greece"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["734485"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["ONCOWORM: Using functional genomics in highly regenerative flatworms to find novel cancer genes"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["Oncoworm"], "Technology_Description": "This project will take direct action in exploiting the powerful planarian model system to achieve novel insights into the molecular processes underpinning oncogenesis and cancer. Based on the principle that biochemical and physiological functions of many genes are conserved across phyla we will identify planarian genes that control the migration, proliferation and differentiation of the highly proliferative pluripotent adult stem cells (pASCs). We will combine a bespoke specially designed partial irradiation assay, bioinformatic and expression based candidate gene identification and the capacity to perform RNAi based screens of gene function to identify novel genes controlling pASCs that are conserved in humans. Those novel genes of greatest promise will then be studied in mammalian cancer cell lines using the insight gleaned from planarians. This project brings together, for the first time, a world-class planarian laboratory with an eminent cancer cell biologist, Dr Kosaka, who will acquire all the expertise required to exploit the planarian system and at the same time transfer his extensive knowledge of cancer biology to the Aboobaker laboratory.", "To": ["2018-04-04, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-04-05"], "Project_ID": ["656816"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM", "KORE TECHNOLOGY LTD", "IONICON ANALYTIK GMBH", "UNIVERZITA KOMENSKEHO V BRATISLAVE", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSITATSMEDIZIN ROSTOCK", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "UNIVERSITAET INNSBRUCK", "STICHTING KATHOLIEKE UNIVERSITEIT", "USTAV FYZIKALNI CHEMIE J. HEYROVSKEHO AV CR, v. v. i."], "EU_Contribution": ["EUR 2 538 628,20"], "Project_Title": ["Ion-Molecule Processes for Analytical Chemical Technologies"], "Total_Cost": ["EUR 2 538 628,20"], "Country": ["United Kingdom", "United Kingdom", "Austria", "Slovakia", "France", "Germany", "Germany", "Austria", "Netherlands", "Czech Republic"], "Project_ACR": ["IMPACT"], "Technology_Description": "Soft chemical-ionization mass-spectrometry (SCIMS) is an exquisitely sensitive analytical technique with applications to health, the environment and security that are vital to the EU. However, the recent, rapid and widespread adoption of this technique has caught Europe unprepared. The resultant shortage in analytical chemical expertise has created an urgent need for highly skilled young researchers to be trained in the wide variety of SCIMS methods. IMPACT addresses this skills\u2019 shortage by establishing an intersectoral and multidisciplinary SCIMS training network. IMPACT also brings cohesion to the fragmented SCIMS research and development activities within the EU. To date, most SCIMS developments have been driven not by users but by manufacturers, whose main focus has been on increased sensitivity. However, just as crucial is improved selectivity. Indeed, many users consider improved selectivity to be the key to taking SCIMS technology to a whole new level. Instead of private and public sectors working independently, we need a fresh, intersectoral approach. IMPACT will achieve this through intersectoral work packages and multidisciplinary research projects. In place of major and costly changes in instrumental design, IMPACT\u2019s projects will focus on developing new methods for improved chemical specificity by manipulating ion chemistry. Hence, IMPACT\u2019s fresh approach will produce a step change in SCIMS instrumentation to deliver both economic and societal benefit to the EU. Specifically, IMPACT will train 10 ESRs within an integrated partnership of commercial, governmental and academic organisations, with planned secondments, 5 Advanced Training Courses, 7 interactive Complementary Skills Workshops, and 4 ESR Centred Research Meetings. IMPACT will therefore provide Europe with both a world-class capability in SCIMS technology and a cohort of highly trained researchers who will bring the benefits of that technology to citizens across the EU.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2016-01-01"], "Project_ID": ["674911"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["CONSIGLIO NAZIONALE DELLE RICERCHE", "UNIVERSITE PARIS DESCARTES", "STIFTUNG FRANKFURT INSTITUTE FOR ADVANCED STUDIES", "TECHNISCHE UNIVERSITAT DARMSTADT"], "EU_Contribution": ["EUR 3 481 874,75"], "Project_Title": ["Goal-based Open-ended Autonomous Learning Robots"], "Total_Cost": ["EUR 3 481 875"], "Country": ["Italy", "France", "Germany", "Germany"], "Project_ACR": ["GOAL-Robots"], "Technology_Description": "This project aims to develop a new paradigm to build open-ended learning robots called `Goal-based Open-ended Autonomous Learning' (GOAL). GOAL rests upon two key insights. First, to exhibit an autonomous open-ended learning process, robots should be able to self-generate goals, and hence tasks to practice. Second, new learning algorithms can leverage self-generated goals to dramatically accelerate skill learning. The new paradigm will allow robots to acquire a large repertoire of flexible skills in conditions unforeseeable at design time with little human intervention, and then to exploit these skills to efficiently solve new user-defined tasks with no/little additional learning. This innovation will be essential in the design of future service robots addressing pressing societal needs. The project will develop the GOAL paradigm by pursuing three main objectives: (1) advance our understanding of how goals are formed and underlie skill learning in children; (2) develop innovative computational architectures and algorithms supporting (2a) the self-generation of useful goals based on user/task independent mechanisms such as intrinsic motivations, and (2b) the use of such goals to efficiently and autonomously build large repertoires of skills; (3) demonstrate the potential of GOAL with a series of increasingly challenging demonstrators in which robots will autonomously develop complex skills and use them to solve difficult challenges in real-life scenarios. The interdisciplinary project consortium is formed by leading international roboticists, computational modelers, and developmental psychologists working with complementary approaches. This will allow the project to greatly advance our understanding of the fundamental principles of open-ended learning and to produce a breakthrough in the field of autonomous robotics by producing for the first time robots that can autonomously accumulate complex skills and knowledge in a truly open-ended way.", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-1-2014 - FET-Open research projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-11-01"], "Project_ID": ["713010"], "Call_for_Proposal": ["H2020-FETOPEN-2014-2015-RIA"]}, -{"Partners": ["POLITECNICO DI TORINO", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "TEL AVIV UNIVERSITY", "UNIWERSYTET WARSZAWSKI", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "ENVISENS TECHNOLOGIES SRL", "PENTALUM TECHNOLOGIES LTD", "SITAEL SPA"], "EU_Contribution": ["EUR 3 555 982,80"], "Project_Title": ["Cloud-MicroPhysics-Turbulence-Telemetry: An inter-multidisciplinary training network for enhancing the understanding and modeling of atmospheric clouds"], "Total_Cost": ["EUR 3 555 982,80"], "Country": ["Italy", "United Kingdom", "Germany", "Israel", "Poland", "France", "Italy", "Israel", "Italy"], "Project_ACR": ["COMPLETE"], "Technology_Description": "Clouds are the largest source of uncertainty in weather prediction, climate science, and remain a weak link in modeling atmospheric circulation. This is rooted in the fact that clouds depend on the physical and chemical processes over a huge range of scales, from the collisions of micron-sized droplets and particles to the airflow dynamics on the scales of thousands of meters. Since ambiguities related to representation of clouds in climate models prevail, explorative observations are still needed. The challenge is on the one hand to establish connections across this range of scales, from aerosol and particle microphysics to macro-scale turbulent dynamics in clouds, and on the other to combine knowledge and training across vastly different scientific and engineering disciplines. The aim of COMPLETE is to develop an inter/multidisciplinary training network that will prepare high-potential early stage researchers (ESRs) with both scientific and industrially-oriented skills that will advance our understanding in these multi-scale complex natural phenomena. COMPLETE will vastly improve Europe\u2019s position as a global leader in technology, science and innovation to address climate change challenges. The training programme will combine the scientific investigation of specific aspects of cloud physics and related turbulent dynamics with training in key professional skills. This comprises an exceptional experimental programme that includes field experiments, laboratory and numerical simulations, the design and development of advanced fast temperature probes, velocity MEMS and innovative atmospheric mini radio-sondes; all aimed at the production of new, Lagrangian based, cloud fluctuation datasets, required to reduce the fragmentation of results and knowledge in this field.", "To": ["2020-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-06-01"], "Project_ID": ["675675"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["UNIVERSITAT POLITECNICA DE CATALUNYA", "GEORG-AUGUST-UNIVERSITAT GOTTINGENSTIFTUNG OFFENTLICHEN RECHTS", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS", "INSTITUTO DE MICROCIRUGIA OCULAR DOS SLP", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIWERSYTET MIKOLAJA KOPERNIKA W TORUNIU", "UNIVERSITY OF GLASGOW", "PICOQUANT INNOVATIONS GMBH"], "EU_Contribution": ["EUR 3 495 300,48"], "Project_Title": ["Advanced BiomEdical OPTICAL Imaging and Data Analysis"], "Total_Cost": ["EUR 3 495 300,48"], "Country": ["Spain", "Germany", "Germany", "United Kingdom", "Spain", "France", "Poland", "United Kingdom", "Germany"], "Project_ACR": ["BE-OPTICAL"], "Technology_Description": "Biomedical imaging is a research field that is producing ground breaking scientific discoveries that enhance the health and life quality of European citizens and have a huge economic impact. In order to maintain Europe\u2019s leading position in the field, it is crucial to invest in the people who will lead R&D, and to promote the academic-private sector partnerships that will transfer the novel technologies to the market. ", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-10-01"], "Project_ID": ["675512"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["FUNDACIO CENTRE DE REGULACIO GENOMICA", "INSTITUT CURIE", "EUVITRO SLU", "THE FRANCIS CRICK INSTITUTE LIMITED", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "LEAD DISCOVERY CENTER GMBH", "TECHNISCHE UNIVERSITAET DRESDEN", "EUROPEAN MOLECULAR BIOLOGY LABORATORY", "CHERRY BIOTECH"], "EU_Contribution": ["EUR 2 802 399,48"], "Project_Title": ["A multidisciplinary approach to cell division: From human oocyte to synthetic biology"], "Total_Cost": ["EUR 2 802 399,48"], "Country": ["Spain", "France", "Spain", "United Kingdom", "Germany", "Germany", "Germany", "Germany", "France"], "Project_ACR": ["DivIDe"], "Technology_Description": "The cell is the universal unit of living matter, and there cannot be propagation of life without cell division. DivIDe aims to investigate the mechanisms and principles of cell division and to reproduce them in vitro with synthetic approaches. Crucial to cell division is the mitotic spindle, a structure whose main duty is the separation of chromosomes. The spindle is made of microtubules (MT), molecular motors, and MT-binding factors, some of which show astounding complexity. The mitotic spindle is the one of the cellular structures that best represents the ability of biological matter to self-organize though arrays of dynamic protein-protein interactions. It rapidly assembles when cells enter mitosis, and it disassembles, after sister chromatid separation and mitotic exit. The complexity and dynamic behaviour of the mitotic spindle captures the imagination of synthetic biologists and modellers. These \u201cmolecular engineers\u201d try to understand and harness the principles of self-organization to generate new biological structures endowed with the most typical features of biological matter, the ability to harness energy to do mechanical or chemical work. The emerging discipline of synthetic biology aims to bring together modellers, physicists, and chemists, with biochemists, structural biologists and cell biologists. So does DivIDe, which will train a new generation of molecular engineers endowed with a strong basis in quantitative computational and biochemical methods, and therefore capable of addressing cellular and molecular mechanisms. Furthermore, molecular engineering harbours industrial applications, and DivIDe will continuously provide results for potential exploitation by the three SME partners. Training in management skills, conceptual and ethical thinking, communication and networking will complement the scientific offer. In summary, DivIDe will be able to teach an integrated package of skills and will train the molecular biologists of the future.", "To": ["2020-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-04-01"], "Project_ID": ["675737"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["ACADEMISCH ZIEKENHUIS LEIDEN", "LUDGER LTD", "GENOS DOO ZA VJESTACENJE I ANALIZU", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "STICHTING VU", "ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA", "FACULDADE DE CIENCIAS MEDICAS DA UNIVERSIDADE NOVA DE LISBOA", "NOVA ID FCT - ASSOCIACAO PARA A INOVACAO E DESENVOLVIMENTO DA FCT", "STICHTING VUMC"], "EU_Contribution": ["EUR 3 293 890,66"], "Project_Title": ["Exploiting Glycosylation of Colorectal Cancer for the development of improved diagnostics and therapeutics"], "Total_Cost": ["EUR 3 293 890,66"], "Country": ["Netherlands", "United Kingdom", "Croatia", "Germany", "France", "Netherlands", "Italy", "Portugal", "Portugal", "Netherlands"], "Project_ACR": ["GlyCoCan"], "Technology_Description": "Colorectal cancer (CRC) is a major worldwide cancer burden with about 1.4 million cases in 2012 and an annual mortality of approximately 700,000. Early detection is crucial as treatment is most efficient in early stages where population based screenings could substantially reduce incidence and mortality.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["676421"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "STIFTUNG DEUTSCHES ELEKTRONEN-SYNCHROTRON DESY", "ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "INSTITUT ZA NUKLEARNE NAUKE VINCA", "TEL AVIV UNIVERSITY", "AKADEMIA GORNICZO-HUTNICZA IM. STANISLAWA STASZICA W KRAKOWIE", "THE UNIVERSITY OF LIVERPOOL", "UNIVERSITE DE STRASBOURG", "UNIVERSITE PARIS-SUD", "INTER-UNIVERSITY RESEARCH INSTITUTE CORPORATION, HIGH ENERGY ACCELERATOR RESEARCH ORGANISATION", "NATIONAL UNIVERSITY CORPORATION THEUNIVERSITY OF TOKYO", "NATIONAL UNIVERSITY CORPORATION TOHOKU UNIVERSITY", "NATIONAL UNIVERSITY CORPORATION KYUSHU UNIVERSITY"], "EU_Contribution": ["EUR 1 179 000"], "Project_Title": ["Europe-Japan Accelerator Development Exchange Programme"], "Total_Cost": ["EUR 2 281 500"], "Country": ["Switzerland", "France", "France", "Spain", "Germany", "United Kingdom", "United Kingdom", "Serbia", "Israel", "Poland", "United Kingdom", "France", "France", "Japan", "Japan", "Japan", "Japan"], "Project_ACR": ["E-JADE"], "Technology_Description": "The Europe-Japan Accelerator Development Exchange Programme (E-JADE) addresses the urgent need of exchange of ideas on R&D and implementation of future accelerators for particle physics. It does so by exchanging accelerator scientists and experts between Europe and Japan.", "To": ["2018-12-31, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Switzerland"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-01-01"], "Project_ID": ["645479"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["TECHNISCHE UNIVERSITAET MUENCHEN", "TECHNISCHE UNIVERSITAET MUENCHEN", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 872 500"], "Project_Title": ["Cell biology of myelin wrapping, plasticity and turnover"], "Total_Cost": ["EUR 1 872 500"], "Country": ["Germany", "Germany", "Germany"], "Project_ACR": ["Myelination"], "Technology_Description": "The myelin sheath is a plasma membrane extension that is laid down in regular spaced segments along axons of the nervous system. In the central nervous system it is formed by oligodendrocytes that spirally wrap their plasma membrane around axons to generate a highly abundant, tightly packed stack of membranes with unique structural properties. Previously, myelin has been regarded as an inert and purely insulating membrane, but it now appears that myelin is metabolically active, providing metabolic support to the underlying axon and participating in information processing by modulating velocity and synchronicity of nerve impulses in neuronal networks. In addition, myelination is not limited to the period of early post-natal development, but continuous into adulthood where it appears to be regulated by neuronal stimuli. This paradigm shift should be fuelled by new knowledge about myelin biology. Here, we plan to fill this gap by addressing the molecular basis of myelin growth, plasticity and remodelling. We will determine the factors that determine whether and to what extent an axon will be myelinated or not, the forces that drive myelin around the axon, the structural basis of myelin plasticity and the mechanisms of myelin turnover in the adult. We will test the hypothesis that microglia actively participate in myelin turnover by taking up myelin fragments that pinch off from the myelin sheath. To realize these aims we plan to pursue an integrative and multidisciplinary approach by bringing together genetics, biochemistry, proteomics and imaging in various model systems. The innovation arises from the combination of high-resolution imaging with molecular approaches in different cell types to obtain a unifying mechanistic understanding of myelin formation, maintenance and degradation. If successful, the project would not only explain how myelin is generated during brain development, but also give insight into how myelin plasticity could fine-tune neuronal networks.", "To": ["2020-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2015-08-01"], "Project_ID": ["647168"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "THE REGENTS OF THE UNIVERSITY OF CALIFORNIA"], "EU_Contribution": ["EUR 2 283 747"], "Project_Title": ["Radiocarbon constraints for models of C cycling in terrestrial ecosystems: from process understanding to global benchmarking"], "Total_Cost": ["EUR 2 283 747"], "Country": ["Germany", "Germany", "United States"], "Project_ACR": ["14Constraint"], "Technology_Description": "The overall goal of 14Constraint is to enhance the availability and use of radiocarbon data as constraints for process-based understanding of the age distribution of carbon in and respired by soils and ecosystems. Carbon enters ecosystems by a single process, photosynthesis. It returns by a range of processes that depend on plant allocation and turnover, the efficiency and rate of litter decomposition and the mechanisms stabilizing C in soils. Thus the age distribution of respired CO2 and the age of C residing in plants, litter and soils are diagnostic properties of ecosystems that provide key constraints for testing carbon cycle models. Radiocarbon, especially the transit of \u2018bomb\u2019 14C created in the 1960s, is a powerful tool for tracing C exchange on decadal to centennial timescales. 14Constraint will assemble a global database of existing radiocarbon data (WP1) and demonstrate how they can constrain and test ecosystem carbon cycle models. WP2 will fill data gaps and add new data from sites in key biomes that have ancillary data sufficient to construct belowground C and 14C budgets. These detailed investigations will focus on the role of time lags caused in necromass and fine roots, as well as the dynamics of deep soil C. Spatial extrapolation beyond the WP2 sites will require sampling along global gradients designed to explore the relative roles of mineralogy, vegetation and climate on the age of C in and respired from soil (WP3). Products of this 14Constraint will include the first publicly available global synthesis of terrestrial 14C data, and will add over 5000 new measurements. This project is urgently needed before atmospheric 14C levels decline to below 1950 levels as expected in the next decade.", "To": ["2021-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Higher or Secondary Education Establishments"], "From": ["2016-12-01"], "Project_ID": ["695101"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN", "UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN", "THE UNIVERSITY OF WARWICK", "UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 1 579 298,75"], "Project_Title": ["Integrable Random Structures"], "Total_Cost": ["EUR 1 579 298,75"], "Country": ["Ireland", "Ireland", "United Kingdom", "United Kingdom"], "Project_ACR": ["IntRanSt"], "Technology_Description": "The last few years have seen significant advances in the discovery and development of integrable models in probability, especially in the context of random polymers and the Kardar-Parisi-Zhang (KPZ) equation. Among these are the semi-discrete (O'Connell-Yor) and log-gamma (Seppalainen) random polymer models. Both of these models can be understood via a remarkable connection between the geometric RSK correspondence (a geometric lifting, or de-tropicalization, of the classical RSK correspondence) and the quantum Toda lattice, the eigenfunctions of which are known as Whittaker functions. This connection was discovered by the PI and further developed in collaboration with Corwin, Seppalainen and Zygouras. In particular, we have recently introduced a powerful combinatorial framework which underpins this connection. I have also explored this connection from an integrable systems point of view, revealing a very precise relation between classical, quantum and stochastic integrability in the context of the Toda lattice and some other integrable systems. The main objectives of this proposal are (1) to further develop the combinatorial framework in several directions which, in particular, will yield a wider family of integrable models, (2) to clarify and extend the relation between classical, quantum and stochastic integrability to a wider setting, and (3) to study thermodynamic and KPZ scaling limits of Whittaker functions (and associated measures) and their applications. The proposed research, which lies at the interface of probability, integrable systems, random matrices, statistical physics, automorphic forms, algebraic combinatorics and representation theory, will make novel contributions in all of these areas.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["669306"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["ISTITUTO NAZIONALE DI ASTROFISICA", "UNIVERSITY OF LEICESTER", "STICHTING SRON NETHERLANDS INSTITUTE FOR SPACE RESEARCH", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "NATIONAL OBSERVATORY OF ATHENS", "THALES ALENIA SPACE ITALIA SPA", "DANMARKS TEKNISKE UNIVERSITET", "CENTRUM ASTRONOMICZNE IM. MIKOLAJAKOPERNIKA POLSKIEJ AKADEMII NAUK", "UNIVERSITA DEGLI STUDI DI FERRARA", "UNIVERSITA DEGLI STUDI DI PERUGIA", "UNIVERSITE DE LIEGE", "UNIVERSITA DEGLI STUDI DI GENOVA", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "Teknologian tutkimuskeskus VTT Oy", "LANCASTER UNIVERSITY", "CESKE VYSOKE UCENI TECHNICKE V PRAZE", "UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN", "UNIVERSITA DEGLI STUDI DI PALERMO", "TARTU OBSERVATORY - ESTONIAN MINISTRY OF EDUCATION AND RESEARCH", "UNIVERSIDAD DE ALICANTE", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "EBERHARD KARLS UNIVERSITAET TUEBINGEN", "LABORATORIO DE INSTRUMENTACAO E FISICA EXPERIMENTAL DE PARTICULAS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSITE DE GENEVE", "ISTITUTO NAZIONALE DI FISICA NUCLEARE"], "EU_Contribution": ["EUR 4 982 477"], "Project_Title": ["Integrated Activities for the High Energy Astrophysics Domain"], "Total_Cost": ["EUR 5 085 247"], "Country": ["Italy", "United Kingdom", "Netherlands", "Germany", "Greece", "Italy", "Denmark", "Poland", "Italy", "Italy", "Belgium", "Italy", "France", "Finland", "United Kingdom", "Czech Republic", "Ireland", "Italy", "Estonia", "Spain", "Spain", "Germany", "Portugal", "France", "Switzerland", "Italy"], "Project_ACR": ["AHEAD"], "Technology_Description": "We propose a set of integrated Activities in the High Energy Astrophysics Domain (AHEAD) in response to the INFRAIA-2014-2015 call Research Infrastructures for High EnergyAstrophysics.", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["INFRAIA-1-2014-2015 - Integrating and opening existing national and regional research infrastructures of European interest"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Jiri Matas", "Tel.: +420 22435721", "Fax: +420 224357385", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2015-09-01"], "Project_ID": ["654215"], "Call_for_Proposal": ["H2020-INFRAIA-2014-2015"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA"], "EU_Contribution": ["EUR 2 492 500"], "Project_Title": ["Quantum Spectroscopy: exploring new states of matter out of equilibrium"], "Total_Cost": ["EUR 2 492 500"], "Country": ["Germany", "Germany", "Spain"], "Project_ACR": ["QSpec-NewMat"], "Technology_Description": "This project addresses the development of novel theoretical and computational tools that utilize the quantum nature of light to understand and control quantum phenomena in complex systems in and out of equilibrium. Some examples of these processes include exciton-exciton interaction, quantum coherence, assisted energy and charge transport, photochemistry, and new states of matter. ", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["694097"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["AARHUS UNIVERSITET", "MEDIZINISCHE HOCHSCHULE HANNOVER", "HELMHOLTZ-ZENTRUM FUER INFEKTIONSFORSCHUNG GMBH", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "UNIVERSITAIR MEDISCH CENTRUM UTRECHT", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "UNIVERSITA DEGLI STUDI DI TORINO", "AARHUS UNIVERSITETSHOSPITAL", "Janssen Vaccines and Prevention B.V."], "EU_Contribution": ["EUR 3 961 943,28"], "Project_Title": ["Training network providing cutting-EDGE knowlEDGE on Herpes Virology and Immunology"], "Total_Cost": ["EUR 3 961 943,28"], "Country": ["Denmark", "Germany", "Germany", "United Kingdom", "Netherlands", "Germany", "Italy", "Denmark", "Netherlands"], "Project_ACR": ["EDGE"], "Technology_Description": "Herpesviruses are widely spread, and cause life-long infections. Most individuals carry multiple herpesviruses, which can cause severe diseases, especially in children, immunocompromised individuals, and elderly. There are currently no safe vaccines against herpesvirus infections and current treatments are not satisfactory. With new insights into the molecular basis for diseases caused by immunodeficiency, and with the increasing numbers of elderly in Europe, there is now an unmet demand for improved treatments of herpesvirus infections. Combined with the progress in basic herpesvirus research, this calls for education of a new generation of scientists with strong research skills, advanced insights into disease mechanisms, and understanding of how industry brings innovative research into the market. In this application we propose an interactive education program for early stage researchers (ESR) in leading European laboratories, hospitals, and biotech companies. The focus will be on the virology and immunology of herpesvirus infections in the context of basic research as well as application of research-acquired knowledge. Our program will prepare the ESRs to manage goal-oriented interactions between academia, the clinics, and the biotech industry. The ESRs will acquire broad theoretical and methodological expertises involving several sectors to obtain the skills required for overcoming the cultural gaps From Bench to Bedside and From Discovery to Innovation. This can only be achieved through a network-based approach. We propose to develop a platform to educate the next generation of scientists to solve the outstanding problems in prevention and treatment of herpesvirus infections. The ESRs will be ideally trained to translate cutting-edge discoveries to novel products and to innovative treatment serving the European people, and hence to improve handling of present and emerging health challenges, as well as to foster the European biopharmaceutical industry sector.", "To": ["2020-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-05-01"], "Project_ID": ["675278"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN", "JOHN INNES CENTRE", "UNIVERSITAET FUER BODENKULTUR WIEN", "UNIVERSITAT ZURICH", "KOBENHAVNS UNIVERSITET", "THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN", "ENVIROTECH INNOVATIVE PRODUCTS LTD", "JUSTUS-LIEBIG-UNIVERSITAET GIESSEN", "LEIBNIZ - INSTITUT FUER PFLANZENGENETIK UND KULTURPFLANZENFORSCHUNG", "TEAGASC - AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY"], "EU_Contribution": ["EUR 4 013 668,80"], "Project_Title": ["CEREALPATH - Training in innovative and integrated control of cereal diseases"], "Total_Cost": ["EUR 4 013 668,80"], "Country": ["Ireland", "United Kingdom", "Austria", "Switzerland", "Denmark", "Ireland", "Ireland", "Germany", "Germany", "Ireland"], "Project_ACR": ["CEREALPATH"], "Technology_Description": "There is a massive and urgent effort needed to ensure security of food supply for the growing world population. This challenge of doubling crop yields by 2050 provides the motivation for this project, entitled Cereal Pathology \u2013 training in innovative and integrated control of cereal diseases (CEREALPATH). Cereals are the most important source of human calories, but we lose billions of euro worth of grain annually due to diseases that reduce yield. CEREALPATH is a multidisciplinary, multisectoral training programme built using the complimentary expertise from 22 participants from 8 European countries, including 7 Universities, 3 research institutes, 11 industry and one regulatory agency. The consortium will combine and share expertise in different approaches to disease control to offer standardized, high quality doctoral training at an advanced level to 15 ESRs. CEREALPATH will expose researchers to research and innovation in both industry and academia. The training equips researchers with the skills and opportunities to develop innovative methods contributing to integrated disease control programmes, thus matching their potential to the jobs of the future and helping Europe and the world meet the critical need of global food security.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations"], "From": ["2015-09-01"], "Project_ID": ["674964"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "KUNGLIGA TEKNISKA HOEGSKOLAN"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Dynamics and transport of quantum matter --- exploring the interplay of topology, interactions and localization"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Germany", "Germany", "Sweden"], "Project_ACR": ["QUANTMATT"], "Technology_Description": "Quantum matter is condensed matter which properties are dominated by the quantum nature of its constituents. The two most fundamental properties of quantum mechanics are interference and entanglement. How do these properties, and their derivatives, show up in an experiment? And how does one control them? These are the fundamental questions addressed in this proposal.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["679722"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["INSTITUTO DE MEDICINA MOLECULAR", "Faculdade de Farm\u00e1cia da Universidade de Lisboa", "UNIVERSITY COLLEGE LONDON", "UNIVERSITAET ULM", "UNIVERSIDAD DE LA RIOJA", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "INSTITUT CURIE", "UNIVERSITAT WIEN", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 2 542 770,72"], "Project_Title": ["A training network for the chemical site-selective modification of proteins: Preparation of the next-generation of therapeutic chemically-defined protein conjugates"], "Total_Cost": ["EUR 2 542 771,03"], "Country": ["Portugal", "Portugal", "United Kingdom", "Germany", "Spain", "United Kingdom", "France", "Austria", "Germany"], "Project_ACR": ["ProteinConjugates"], "Technology_Description": "ProteinConjugates is an inter- and multi-disciplinary network for the education of talented young scientists who will learn how to rationally design and construct the next generation of chemically-defined and innovative protein drug-conjugates for the targeted treatment of serious conditions such as cancer or rheumatoid arthritis. A complementary interaction between academy and pharmaceutical industry is at the centre of such a network, which involves 8 academic groups and 1 SME partner as beneficiaries, and 2 leading European industrial partner organizations that will host secondments while providing training. The combined expertise of the beneficiaries and industrial partners in synthesis of complex molecules, molecular dynamics, supramolecular self-assembly, site-selective chemical protein modification, protein/antibody engineering, cancer therapeutics and drug development together with the experience in project management and training of PhDs and Postdocs of the PIs, will create a multidisciplinary environment where 10 young researchers can foster their knowledge and skills while developing the most innovative ideas in the emerging fields of chemical site-selective protein modification and protein biotherapeutics. Exposure to the highly dynamic and multidisciplinary ProteinConjugates environment will contribute to the education of the next generation of leaders in the emerging field of protein biotherapeutics, a key area of research and drug development for Europe's competitiveness.", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Portugal"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2015-11-01"], "Project_ID": ["675007"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN"], "EU_Contribution": ["EUR 1 338 500"], "Project_Title": ["Wavefunctions for strongly correlated systems"], "Total_Cost": ["EUR 1 338 500"], "Country": ["Germany", "Germany", "Germany"], "Project_ACR": ["WASCOSYS"], "Technology_Description": "Strongly correlated quantum systems, which are at the heart of many open problems in condensed matter,", "To": ["2020-02-29, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Higher or Secondary Education Establishments"], "From": ["2015-03-01"], "Project_ID": ["636201"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["UNIVERSITE LIBRE DE BRUXELLES", "UNIVERSITE LIBRE DE BRUXELLES"], "EU_Contribution": ["EUR 2 250 000"], "Project_Title": ["Role of Apolipoproteins L in immunity and disease"], "Total_Cost": ["EUR 2 250 000"], "Country": ["Belgium", "Belgium"], "Project_ACR": ["APOLs"], "Technology_Description": "Work conducted in my laboratory on the trypanosome killing factor of human serum led to the identification", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["669007"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM", "FEMTONICS KUTATO ES FEJLESZTO KORLATOLT FELELOSSEGU TARSASAG", "MAGYAR TUDOMANYOS AKADEMIA WIGNER FIZIKAI KUTATOKOZPONT", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "PECSI TUDOMANYEGYETEM - UNIVERSITY OF PECS"], "EU_Contribution": ["EUR 4 271 481,25"], "Project_Title": ["Visual genetics: establishment of a new discipline to visualize neuronal nuclear functions in real-time in intact nervous system by 4D Raman spectroscopy"], "Total_Cost": ["EUR 4 271 481,25"], "Country": ["United Kingdom", "Hungary", "Hungary", "Germany", "Hungary"], "Project_ACR": ["NEURAM"], "Technology_Description": "Due to technical constraints the observation and analysis of endogenous transcriptional processes in living and functioning organisms is not feasible today. Therefore our understanding of the nuclear processes and the options to diagnose or intervene at genetic level is seriously constrained. Our proposal offers a cutting-edge technique to overcome this limitation. The aim is to visualize nuclear processes in intact brain in real-time leading to a new high-tech product development, prototype scientific equipment at the research institutes and in the long run new tools to study and cure human diseases. The main objectives are to: 1) develop Stimulated Raman Spectroscopy (SRS)-based technologies to visualize endogenous transcription at single cell and single gene level; 2) develop tools for loading alkyne-tagged nucleosides and nucleotide analogues into neurons; 3) distinguish neuron types without labelling by SRS; 4) track transcription processes in intact brain with high temporal and spatial resolution; 5) study link between single gene function and behavior; 5) develop and commercialise a 4D-SRS microscope for broad range of applications. The combination of label-free neuron mapping and visualization of nuclear activity at single gene level provides a new level of information of the structural and functional organization of the brain.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-1-2014 - FET-Open research projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["712821"], "Call_for_Proposal": ["H2020-FETOPEN-2014-2015-RIA"]}, -{"Partners": ["UNIVERSITE DE STRASBOURG", "BASF SE", "KATHOLIEKE UNIVERSITEIT LEUVEN", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "UNIVERSITE DE MONS", "HUMBOLDT-UNIVERSITAET ZU BERLIN", "KARLSRUHER INSTITUT FUER TECHNOLOGIE", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "CONSIGLIO NAZIONALE DELLE RICERCHE", "UNIVERSITY COLLEGE LONDON", "SCRIBA NANOTECNOLOGIE SRL"], "EU_Contribution": ["EUR 3 826 359,72"], "Project_Title": ["Integrated self-assembled SWITCHable systems and materials: towards responsive organic electronics \u2013 a multi-site innovative training action"], "Total_Cost": ["EUR 3 826 359,72"], "Country": ["France", "Germany", "Belgium", "Spain", "Belgium", "Germany", "Germany", "Germany", "Italy", "United Kingdom", "Italy"], "Project_ACR": ["iSwitch"], "Technology_Description": "iSwitch will offer top-level multi-disciplinary and supra-sectorial training to a pool of talented young researchers, involving contributions from different scientific and technological fields such as, supramolecular chemistry, materials, nanoscience, physics and engineering. iSwitch\u2019s appointees will be trained through lecture courses, dedicated international schools and workshops, topical conferences, secondments to other consortium nodes and an ambitious and carefully planned research activities benefiting from the expertise of world-leading senior PIs and of younger but well-established PIs with outstanding track records in training and research. Additionally, iSwitch will generate new ground-breaking S&T knowledge needed to obtain efficient and fast switching in supramolecular electro- and opto-active materials as a response to external stimuli. This will be accomplished via controlled self-assembly of multicomponent architectures incorporating molecular switches, for fabricating responsive and multifunctional optoelectronic supramolecular devices. We are particularly interested in developing nano- and macro-scale switchable transistors and light-emitting devices as new solutions to (nanoscale) multifunctional organic-based logics.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["642196"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["TECHNISCHE UNIVERSITAET MUENCHEN", "UNIVERSITA DEGLI STUDI DI TRENTO", "UNIVERSITY OF DURHAM", "STIFTUNG FRANKFURT INSTITUTE FOR ADVANCED STUDIES", "LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN", "RSK TEHNOLOGII ZAO", "BAYERISCHE FORSCHUNGSALLIANZ BAVARIAN RESEARCH ALLIANCE GMBH"], "EU_Contribution": ["EUR 2 795 000"], "Project_Title": ["An Exascale Hyperbolic PDE Engine"], "Total_Cost": ["EUR 2 872 500"], "Country": ["Germany", "Italy", "United Kingdom", "Germany", "Germany", "Russia", "Germany"], "Project_ACR": ["ExaHyPE"], "Technology_Description": "Many aspects of our life, but also cutting-edge research questions, hinge on the solution of large systems of partial differential equations expressing conservation laws. Such equations are solved to compute accurate weather forecast, complex earthquake physics, hematic flows in patients, or the most catastrophic events in the universe. Yet, our ability to exploit the predictive power of these models is still severely limited by the computational costs of their solution. Thus, the simulation of earthquakes and their induced hazards is not yet accurate enough to prevent human losses. And our ability to model astrophysical objects is still insufficient to explain our observations.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["FETHPC-1-2014 - HPC Core Technologies, Programming Environments and Algorithms for Extreme Parallelism and Extreme Data Applications"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other"], "From": ["2015-10-01"], "Project_ID": ["671698"], "Call_for_Proposal": ["H2020-FETHPC-2014"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "UNIVERSITEIT UTRECHT", "THERMO FISHER SCIENTIFIC (BREMEN) GMBH"], "EU_Contribution": ["EUR 3 672 625"], "Project_Title": ["Mass spectrometric technology for next generation proteomics in systems medicine"], "Total_Cost": ["EUR 5 038 875"], "Country": ["Denmark", "Germany", "Netherlands", "Germany"], "Project_ACR": ["MSmed"], "Technology_Description": "Systems medicine designates the application of global approaches to human health and disease. Genomic technologies, especially next-generation sequencing, are already pioneering this new area. There is an urgent need to advance proteomics technologies to a similar level. This will help revolu\u00actionize diagnosis and prognosis based on the expression levels and modifications of proteins in cells, tissues, organoids or body fluids. Our vision is to make mass spectrometry so robust and powerful that it will be present in every biological laboratory and in every clinic. ", "To": ["2019-11-30, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-1-2014 - FET-Open research projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-12-01"], "Project_ID": ["686547"], "Call_for_Proposal": ["H2020-FETOPEN-2014-2015-RIA"]}, -{"Partners": ["WEIZMANN INSTITUTE OF SCIENCE", "BAR ILAN UNIVERSITY", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "UNIVERSITE DE GENEVE", "UNIVERSIDAD CARLOS III DE MADRID", "AUGMANITY NANO LTD"], "EU_Contribution": ["EUR 3 979 069"], "Project_Title": ["NanoSmells: Artificial remote-controlled odorants"], "Total_Cost": ["EUR 3 979 069"], "Country": ["Israel", "Israel", "Germany", "Switzerland", "Spain", "Israel"], "Project_ACR": ["NanoSmell"], "Technology_Description": "Despite years of promise, an odor-emitting component in devices such as televisions, phones, computers and more has yet to be developed. Two major obstacles in the way of such development are poor understanding of the olfactory code (the link between odorant structure, neural activity, and odor perception), and technical inability to emit odors in a reversible manner. Here we propose a novel multidisciplinary path to solving this basic scientific question (the code), and in doing so generate a solution to the technical limitation (controlled odor emission). The Bachelet lab will design DNA strands that assume a 3D structure that will specifically bind to a single type of olfactory receptor and induce signal transduction. These DNA-based \"artificial odorants\" will be tagged with a nanoparticle that changes their conformation in response to an external electromagnetic field. Thus, we will have in hand an artificial odorant that is remotely switchable. The Hansson lab will use tissue culture cells expressing insect olfactory receptors, functional imaging, and behavioral tests to validate the function and selectivity of these switchable odorants in insects. The Carleton lab will use imaging in order to investigate the patterns of neural activity induced by these artificial odorants in rodents. The Sobel lab will apply these artificial odorants to the human olfactory system, and measure perception and neural activity following switching the artificial smell on and off. Finally, given a potential role for olfactory receptors in skin, the Del Rio lab will test the efficacy of these artificial odorants in promoting wound healing. At the basic science level, this approach may allow solving the combinatorial code of olfaction. At the technology level, beyond novel pharmacology, we will provide proof-of-concept for countless novel applications ranging from insect pest-control to odor-controlled environments and odor-emitting devices such as televisions, phones, and computers.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-1-2014 - FET-Open research projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-09-01"], "Project_ID": ["662629"], "Call_for_Proposal": ["H2020-FETOPEN-2014-2015-RIA"]}, -{"Partners": ["CITY UNIVERSITY OF LONDON", "CITY UNIVERSITY OF LONDON", "COPENHAGEN BUSINESS SCHOOL"], "EU_Contribution": ["EUR 1 739 387"], "Project_Title": ["Corporate Arbitrage and CPL Maps: Hidden Structures of Controls in the Global Economy"], "Total_Cost": ["EUR 1 739 387"], "Country": ["United Kingdom", "United Kingdom", "Denmark"], "Project_ACR": ["CORPLINK"], "Technology_Description": "Political science conceptualises state-market relations as balancing acts between the public sphere (the state or government) and the private sphere (the market, dominated by large corporate bodies). The expansion of the global market has been led by the rise of large and highly mobile multinational firms. Since many of these companies command turnover comparable to the GDP of middle size states, globalisation is often seen as a global shift of power from states to markets, where corporate power stems from centralisation of resources, capital and structural influence over politics and society. ", "To": ["2020-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-12-01"], "Project_ID": ["694943"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["UNIVERSITA CA' FOSCARI VENEZIA"], "EU_Contribution": ["EUR 262 269"], "Project_Title": ["The Catholic Charismatic Renewal (CCR): an Historical Analysis Between US and Europe"], "Total_Cost": ["EUR 262 269"], "Country": ["Italy"], "Project_ACR": ["CAT-CAM"], "Technology_Description": "The research project aims to analyze the history of the Catholic Charismatic Renewal (CCR), a spiritual awakening movement which was founded in 1967 in the United States of America within the Catholic Church and which spread rapidly throughout the world, so much so that today its has more than 120 million members. The proposal intends to focus on three specific objectives:", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["654994"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["TARTU ULIKOOL"], "EU_Contribution": ["EUR 228 421,80"], "Project_Title": ["Socrates and Plato on Epistemic Authority"], "Total_Cost": ["EUR 228 421,80"], "Country": ["Estonia"], "Project_ACR": ["SPEA"], "Technology_Description": "It often happens that we accept as true what other people tell us, and by doing so, we acquire knowledge about the world. We trust each other, and we often grant teachers and experts authority over our beliefs. The inter-subjective nature of belief formation has recently moved into the very center of epistemology. However, it is rarely mentioned that the reflection on the role of other people in our knowledge-acquisition has a distinguished historical pedigree, one that still deeply affects the way think about these issues. In particular, the Greek philosophers\u2019 treatment of the notions of authority, trust, and disagreement has exerted strong influence on the subsequent history of philosophy. Up to now, however, there has been no systematic study of this important aspect of Greek thought. This project, \u201cSocrates and Plato on Epistemic Authority\u201d, focuses on the role attributed to what philosophers call \u201cepistemic authority\u201d (i.e. authority over belief) in knowledge acquisition and belief formation in the classical era of Ancient Greek philosophy (esp. in Socrates and Plato). Thus, the project aims to improve the understanding of Greek epistemology and to offer a historical background and an independent contribution to a central epistemological topic.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Estonia"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["659241"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON", "DEUTSCHES FORSCHUNGSZENTRUM FUR KUNSTLICHE INTELLIGENZ GMBH", "UNIVERZITA KARLOVA", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "STUDIO GOBO LIMITED", "UNIVERSITAT DES SAARLANDES", "Institute of Science and Technology Austria", "EDINBURGH NAPIER UNIVERSITY"], "EU_Contribution": ["EUR 3 264 733"], "Project_Title": ["Distributed 3D Object Design"], "Total_Cost": ["EUR 3 264 733"], "Country": ["United Kingdom", "Germany", "Czech Republic", "Germany", "United Kingdom", "Germany", "Austria", "United Kingdom"], "Project_ACR": ["DISTRO"], "Technology_Description": "The DISTRO network brings together leading laboratories in Visual Computing and 3D Computer Graphics research across Europe with the aim of training a new generation of scientists, technologists, and entrepreneurs that will move Europe into a leading role in the scientific and technological innovation in the area of casual, distributed 3d object design and customization.", "To": ["2018-12-31, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Corinna Hahn", "Tel.: +49 681 95 92 3362", "Fax: +49 681 95 92 3370", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-01-01"], "Project_ID": ["642841"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["UNIVERSITEIT UTRECHT", "UNIVERSITAT DE GIRONA", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "LEIBNIZ - INSTITUT FUR KATALYSE EV AN DER UNIVERSITAT ROSTOCK", "UNIVERSITAET BERN", "DSM CHEMICAL TECHNOLOGY R & D BV", "KATHOLIEKE UNIVERSITEIT LEUVEN", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "UNIVERSITE DE BRETAGNE OCCIDENTALE"], "EU_Contribution": ["EUR 3 318 634,08"], "Project_Title": ["Non-Noble Metal Catalysis - NoNoMeCat"], "Total_Cost": ["EUR 3 318 634,08"], "Country": ["Netherlands", "Spain", "Switzerland", "Germany", "Switzerland", "Netherlands", "Belgium", "Germany", "France"], "Project_ACR": ["NoNoMeCat"], "Technology_Description": "Transition metal catalysts are formidable tools towards greener chemistry, allowing for low-waste, energy-efficient, and selective reactions. However, the noble metals (Ru, Os, Rh, Ir, Pd, Pt) that are currently most common in homogeneous catalysts suffer from high toxicity and environmental impact in addition to their scarcity and ensuing high cost. First-row metals (Mn, Fe, Co, Ni, Cu) are emerging as environmentally benign alternatives, but to this day rarely equal the performance of their noble counterparts. The NoNoMeCat network aims at providing excellent and structured interdisciplinary training to a generation of young researchers in the field of Non-Noble Metal homogeneous Catalysis who will push the boundaries of the field in terms of catalyst stability, selectivity, mechanistic understanding, and scalability. These challenges are addressed in three areas of high fundamental and practical significance: the oxidation of hydrocarbons, the formation of new C-X bonds (C-C, C-N) bonds through cross-coupling reactions, and clean energy production. NoNoMeCat will enrol 14 Early Stage Researchers (ESRs) who will receive structured training in experimental and theoretical aspects of non-noble metal chemistry as well as transferable skills such as research integrity, scientific communication and public outreach. Tight integration of non-academic partners will expose all ESRs to aspects of both fundamental interdisciplinary research and industrial application, paving the way for long-standing intersectorial collaborations.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["675020"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "UNIVERSITAET STUTTGART", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "ERNST & YOUNG ABOGADOS SLP"], "EU_Contribution": ["EUR 606 198"], "Project_Title": ["Innovative infrastructure for astronomical research based on stratospheric balloons"], "Total_Cost": ["EUR 606 198,75"], "Country": ["Spain", "Germany", "Germany", "Spain"], "Project_ACR": ["ORISON"], "Technology_Description": "ORISON addresses an innovative research infrastructure based on scientific instrumentation integrated into movable stabilized balloon platforms. Many Astronomical observations and experiments are severely limited by the Earth\u2019s atmosphere: atmospheric turbulence, atmospheric absorption, scattering and emissions, bad weather and other phenomena degrade or prevent many astronomical observations. To solve that, scientists utilise specific space missions, such as the Hubble Space Telescope, whose costs are immense and whose availability is highly restricted. ", "To": ["2017-07-31, closed project"], "Meta": [""], "Topic_s": ["INFRASUPP-2-2015 - Innovative procurement pilot action in the field of scientific instrumentation"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-02-01"], "Project_ID": ["690013"], "Call_for_Proposal": ["H2020-INFRASUPP-2015-2"]}, -{"Partners": ["THE HEBREW UNIVERSITY OF JERUSALEM"], "EU_Contribution": ["EUR 278 674,20"], "Project_Title": ["Behavior-dependent interactions between frontal and somatosensory cortices"], "Total_Cost": ["EUR 278 674,20"], "Country": ["Israel"], "Project_ACR": ["AG-GF"], "Technology_Description": "The mammalian brain integrates behaviorally relevant sensory information by recruiting large parts of the neocortex to enable precise perception, apt decisions and adequate actions. The large-scale interactions and the distinct roles of the various neocortical regions, namely frontal motor-related areas and posterior sensory-related regions, remain poorly understood. Here, we aim to characterize how behavior-related activity in higher-order regions (e.g. frontal area) of the mouse is spatiotemporally organized, and how does it relate to lower-order regions (e.g. somatosensory cortex). Mice will be trained on an S1-dependent texture discrimination task under head-fixed conditions, enabling simultaneous imaging of neuronal populations. First, we will use a novel wide-field preparation to map lower and higher-order functions throughout the cortex. Next, we will zoom-in on specific areas of interest using two-photon microscopy to achieve single cell resolution. Finally, we will use an array of labeling techniques to track behavior-dependent activity of neuronal populations that project to a specific area. A special emphasis will be to identify how the activity in subsets of neurons that project \u2018top-down\u2019, from frontal areas to the primary sensory area, relates to different behavioral aspects. We expect that our results will provide fundamental insights into the contribution of frontal cortical regions to perception-related and decision-related activity before sensation (anticipation), during sensation (texture touch) and after sensation (holding in memory and 'licking for reward' action). We believe that this multidisciplinary project in behaving animals is a challenging and promising approach bound to generate novel and exciting results which will be of great interest to the scientific community.", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-08-01"], "Project_ID": ["659719"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI CAMERINO", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "BIOMOLECULAR RESEARCH GENOMICS SRL", "UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA", "EPIGENETIKS GENETIK BIYOINFORMATIK YAZILIM AS", "ELVESYS SAS"], "EU_Contribution": ["EUR 337 500"], "Project_Title": ["Advanced bioinformatics for genome and metagenome analyses and discovery of novel biocatalists from extremophiles: implications for improving industrial bioprocesses"], "Total_Cost": ["EUR 337 500"], "Country": ["Italy", "United Kingdom", "Italy", "Italy", "Turkey", "France"], "Project_ACR": ["MeTABLE"], "Technology_Description": "The aim of this proposal is to acquire new insights about the mechanisms of environmental adaptation, particularly for cold-adapted organisms, and to discover novel metabolic pathways and enzymes with potential industrial value. We intend to accomplish this goal by establishing a collaboration and a knowledge-exchange network between industrial and academic partners aiming at developing bioinformatic tools for genomic analysis and biotechnology tools for directed evolution. The partners present high complementarity: UNICAM holds genomic sequences from psychrophilic and mesophilic ciliates that need to be annotated and analysed. Sabanci provides environmental samples for the isolation and characterization of new extremophiles. CAMBRIDGE provides the know-how for the discovery of new metabolic pathways valuable for understanding environmental adaptation. BMR Genomics and COMSATS possess all the facilities for genome sequencing and annotation and bioinformatic expertise with the purpose of developing new tools to analyse genomes of microorganisms from extreme environment. UNIMIB owns the facilities for the heterologous expression of gene sequences in bacteria and yeasts and technologies to assess and implement the properties of novel enzymes towards industrial application. We are confident that the establishment of the international research network proposed, with its synergistic effects, will significantly contribute to push all the involved laboratories to the top level in the field of production of active biomolecules and in the discovery of mechanisms of molecular adaptation under extreme environmental conditions. These discoveries may help the manufacturing of a new generation of ordinary facilities, as cleaning agents, biofuels, with a significant impact on the everyday life of European citizens.", "To": ["2018-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2014-12-01"], "Project_ID": ["645693"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["TECHNISCHE UNIVERSITAET WIEN", "PHYSIKALISCH-TECHNISCHE BUNDESANSTALT", "LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN", "RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG", "JYVASKYLAN YLIOPISTO", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "TOPTICA PHOTONICS AG"], "EU_Contribution": ["EUR 3 970 327,50"], "Project_Title": ["Towards a nuclear clock with Thorium-229"], "Total_Cost": ["EUR 3 970 327,50"], "Country": ["Austria", "Germany", "Germany", "Germany", "Finland", "Germany", "Germany"], "Project_ACR": ["nuClock"], "Technology_Description": "Atomic clocks are the backbone of our modern communication and navigation technology, e.g. through the global positioning system (GPS). Improving these clocks will open up exciting new applications in geodesy, fleet tracking, autonomous vehicles, augmented reality and shed light on some of the most fundamental questions in research.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-1-2014 - FET-Open research projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-06-01"], "Project_ID": ["664732"], "Call_for_Proposal": ["H2020-FETOPEN-2014-2015-RIA"]}, -{"Partners": ["STICHTING WAGENINGEN RESEARCH", "DEUTSCHES INSTITUT FUER LEBENSMITTELTECHNIK", "EUROPEAN FOOD INFORMATION RESSOURCE AISBL", "INSTITUT JOZEF STEFAN", "WAGENINGEN UNIVERSITY", "UNIVERSITY OF SURREY", "RISE RESEARCH INSTITUTES OF SWEDEN AB", "AALBORG UNIVERSITET", "DE LA CUEVA GONZALEZ COTERA JAVIER", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "EUROPEAN FOOD INFORMATION COUNCIL AISBL", "INSTITUTE OF FOOD RESEARCH", "CONSIGLIO NAZIONALE DELLE RICERCHE", "CENTRE EUROPEEN POUR LA NUTRITION ET LA SANTE", "AALTO-KORKEAKOULUSAATIO", "GS1 DENMARK FORENING"], "EU_Contribution": ["EUR 2 997 283,25"], "Project_Title": ["Research Infrastructure on Consumer Health and Food Intake using E-science with Linked Data Sharing"], "Total_Cost": ["EUR 3 085 299,58"], "Country": ["Netherlands", "Germany", "Belgium", "Slovenia", "Netherlands", "United Kingdom", "Sweden", "Denmark", "Spain", "Switzerland", "Belgium", "United Kingdom", "Italy", "France", "Finland", "Denmark"], "Project_ACR": ["RICHFIELDS"], "Technology_Description": "RICHFIELDS", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["INFRADEV-1-2014 - Design studies"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Netherlands"], "Activity": ["Research Organisations", "Research Organisations", "Other", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Other", "Research Organisations", "Research Organisations", "Other", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-10-01"], "Project_ID": ["654280"], "Call_for_Proposal": ["H2020-INFRADEV-1-2014-1"]}, -{"Partners": ["INSTITUTE OF DEVELOPMENT STUDIES"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Fighting Over Land: Theory and Empirical Evidence from Colombia"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["FOL"], "Technology_Description": "This proposal aims to develop a research agenda on the long-term effect on civil conflict on institutions, particularly on land tenure structure. I start by building a theoretical model to establish the mechanisms and incentives through which actors involved in an armed conflict may be interested on fighting over the control and property rights of rural land. The resulting theoretical hypotheses will be tested using a truly unique, plot-level census data set that I digitised from Official Archives of the province of Antioquia, a Colombian region highly exposed to violence over the last fifty years. This dataset contains plot-level census data collected in 1950-55 for tax purposes. Additionally, I utilise similar plot-level census data for 1995 and 2000. These historical data sets can be easily matched to current cadastral information, available from 2006 onward. Hence, I will have comparable plot-level census datasets from Antioquia for four different periods, which coincide with the main shift of the intensity and expansion of the Colombian conflict. The exogenous nature of the different episodes of the conflict will provide the spatial and temporal variation to identify the effect of violence on land tenure. Several concerns might arise about the potential non-randomness of violence. While I cannot entirely resolve these (i.e. war is not random), I propose different strategies to test the robustness of my results. The contribution of this proposal is twofold. First, this proposal will contribute to the literature on land related conflict and the social consequences of conflict. Second, I provide technical support to many land restitution policies launched in post-conflict settings.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["708448"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "ECOLE NATIONALE DES PONTS ET CHAUSSEES", "ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS", "TECHNOLOGIKO PANEPISTIMIO KYPROU", "RISA SICHERHEITSANALYSEN GMBH", "UAB METIS BALTIC", "EXUS SOFTWARE LTD"], "EU_Contribution": ["EUR 1 845 000"], "Project_Title": ["Transforming Intangible Folkloric Performing Arts into Tangible Choreographic Digital Objects"], "Total_Cost": ["EUR 1 845 000"], "Country": ["Greece", "United Kingdom", "France", "Greece", "Cyprus", "Germany", "Lithuania", "United Kingdom"], "Project_ACR": ["Terpsichore"], "Technology_Description": "Intangible Cultural Heritage (ICH) content means \"the practices, representations, expressions, knowledge, skills \u2013 as well as the instruments, objects, artefacts and cultural spaces associated therewith\". Although, ICH content, especially traditional folklore performing arts, is commonly deemed worthy of preservation by UNESCO (Convention for the Safeguarding of ICH) and the EU Treaty, most of the current research efforts are on the focus is on tangible cultural assets, while the ICH content has been overlooked. The primary difficulty stems by the complex structure of ICH, its dynamic nature, the interaction among the objects and the environment, as well as emotional elements (e.g., the way of expression and dancers' style). TERPSICHORE aims to study, analyse, design, research, train, implement and validate an innovative framework for affordable digitization, modelling, archiving, e-preservation and presentation of ICH content related to folk dances, in a wide range of users (dance professionals, dance teachers, creative industries and general public). The project targets at integrating the latest innovative results of photogrammetry, computer vision, semantic technologies, time evolved modeling, combined with the story telling and folklore choreography. An important output of the project will be a Web based cultural server/viewer with the purpose to allow user\u2019s interaction, visualization, interface with existing cultural libraries (EUROPEANA) and enrichment functionalities to result in virtual surrogates and media application scenarios that release the potential economic impact of the ICH. The final product will support a set of services such as virtual/augmented reality, social media, interactive maps, presentation and learning of European Folk dances with tremendous impact on the European society, culture and tourism.", "To": ["2020-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Greece"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-04-01"], "Project_ID": ["691218"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 174 864,60"], "Project_Title": ["Politics isn\u2019t cool, it\u2019s hot! Do emotions influence political attitudes?"], "Total_Cost": ["EUR 174 864,60"], "Country": ["Netherlands"], "Project_ACR": ["HotPolitics"], "Technology_Description": "Europeans and Americans are anxious about the number of refugees entering their country; angry about unresponsive political elites; or sad how immigrants are treated. To answer the question whether these emotions influence citizens\u2019 political attitudes, the state-of-the-art relies primarily upon self-reported emotions. Yet, when asked to self-report emotions, people are likely to mix their initial emotion with their cognitive evaluation which leads to an invalid measure of the emotion. In HotPolitics, I employ a ground-breaking methodological design by not relying upon self-reported emotions but measuring emotions via the actual physiological responses that citizens experience. Physiological responses are automatic, directed by the autonomous nervous system, when the brain experiences emotion. ", "To": ["2019-09-03, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-04"], "Project_ID": ["750443"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["STIFTUNG DEUTSCHES ELEKTRONEN-SYNCHROTRON DESY", "UNIVERSITE DE GENEVE", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "KARLSRUHER INSTITUT FUER TECHNOLOGIE"], "EU_Contribution": ["EUR 886 500"], "Project_Title": ["SENSE - a roadmap for the ideal low light level sensor development"], "Total_Cost": ["EUR 886 500"], "Country": ["Germany", "Switzerland", "Germany", "Germany"], "Project_ACR": ["SENSE"], "Technology_Description": "Over the last decade substantial improvements were made in the technologies for low light-level detection. It is expected that the coming years may bring a technology revolution in this emerging FET-relevant topic. Various European research groups have played and will play an important role in further advancing this technology since low light-level detection is very important for a lot of research projects and upcoming research infrastructures. Indeed, R&D in this technology is growing and new groups all over Europe and world-wide are getting involved. However, a coordination of these groups \u2013 especially in Europe \u2013 is currently missing; while competition is often speeding up developments especially in the prototyping together with industry, duplication in testing and evaluating available devices for research projects is unfortunately standard.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-3-2015 - Coordination and Support Activities"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["713171"], "Call_for_Proposal": ["H2020-FETOPEN-2015-CSA"]}, -{"Partners": ["POLITECNICO DI MILANO", "FORSCHUNGSVERBUND BERLIN EV", "LUNDS UNIVERSITET", "STIFTUNG DEUTSCHES ELEKTRONEN-SYNCHROTRON DESY", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "AARHUS UNIVERSITET", "AMPLITUDE TECHNOLOGIES SA", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS", "FEMTOLASERS PRODUKTIONS GMBH", "ALBERT-LUDWIGS-UNIVERSITAET FREIBURG"], "EU_Contribution": ["EUR 3 896 869,64"], "Project_Title": ["Molecular Electron Dynamics investigated by IntensE Fields and Attosecond Pulses"], "Total_Cost": ["EUR 3 896 869,64"], "Country": ["Italy", "Germany", "Sweden", "Germany", "Germany", "Denmark", "France", "France", "Greece", "Austria", "Germany"], "Project_ACR": ["MEDEA"], "Technology_Description": "The interaction of matter with light is one of the most fundamental processes occurring in nature with countless scientific and technological applications. In recent years, the continuing development of intense, ultrashort, coherent light sources from the mid-infrared (mid-IR) to the extreme ultraviolet (XUV) spectral range has opened new possibilities for the investigation of this interaction in new and complementary domains. In both the IR and XUV regimes, molecules and clusters of atoms interacting with light exhibit (correlated) multi-electron dynamics evolving on the few femtosecond (1 fs=10-15 s) to attosecond (1 as=10-18 s) timescale. Several experimental and theoretical investigations suggest that ultrafast multielectronic processes might be fundamental in determining the behaviour of molecules and clusters, and that understanding these phenomena might offer new perspectives on processes occurring on \u201cslower\u201d timescales, such as bond-breaking in complex molecules and Coulomb explosion in charged clusters.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2015-01-01"], "Project_ID": ["641789"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "CSC-TIETEEN TIETOTEKNIIKAN KESKUS OY", "TRUST-IT SERVICES LIMITED", "CONSIGLIO NAZIONALE DELLE RICERCHE", "ATHINA-EREVNITIKO KENTRO KAINOTOMIAS STIS TECHNOLOGIES TIS PLIROFOFORIAS, TON EPIKOLNONION KAI TIS GNOSIS", "SCIENCE AND TECHNOLOGY FACILITIES COUNCIL", "ASSOCIATION OF COMMONWEALTH UNIVERSITIES", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "ROYAL IRISH ACADEMY", "BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION", "CAP DIGITAL", "NATIONAL LIBRARY OF IRELAND"], "EU_Contribution": ["EUR 3 999 187,50"], "Project_Title": ["Research Data Alliance - Europe 3"], "Total_Cost": ["EUR 3 999 187,50"], "Country": ["Germany", "Finland", "United Kingdom", "Italy", "Greece", "United Kingdom", "United Kingdom", "France", "Ireland", "Spain", "France", "Ireland"], "Project_ACR": ["RDA Europe"], "Technology_Description": "The Research Data Alliance (RDA) is rapidly building the social and technical bridges that enable open sharing and re-use of data on a global level. RDA/Europe - the European plug-in to the global Research Data Alliance activities \u2013 will ensure that European research, industrial, e-infrastructure and policy stakeholders are all aware of its achievements, engaged with and actively involved in the global RDA activities and will advance the use of its results. European domain scientists and data scientists are involved in and driving a series of working and interest groups, generating first results of RDA and this momentum should be maintained and even increased. A collaborative web platform, currently under strong development, is widely used by the RDA members and coordinating administration. RDA Europe will look for innovative ways of facilitating the take-up and implementation of RDA outputs in Europe, both in academia and industry, and will continue to develop and maintain the RDA web-based collaboration framework. Further steps will be taken in steering, planning and implementing the sustainability of RDA through a legal entity, established in Europe, and investigating the most appropriate business models for long term sustainability. This RDA/Europe proposal will mainly build on the successful consortium of the previous years but strengthen its anchoring at policy, scientific and industrial uptake to drive forward RDA Europe objectives that are all grounded in technological excellence and innovation and have clear international ties. RDA Europe partners are very actively involved in the strategic planning, implementation, marketing & communication of RDA through the governance bodies of RDA.", "To": ["2018-02-28, ongoing project |"], "Meta": [""], "Topic_s": ["EINFRA-3-2014 - Towards global data e-infrastructures \u2013 Research Data Alliance"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Research Organisations", "Research Organisations", "Other", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2015-09-01"], "Project_ID": ["653194"], "Call_for_Proposal": ["H2020-EINFRA-2014-2"]}, -{"Partners": ["LANCASTER UNIVERSITY", "UNIVERSITY OF CYPRUS", "UNIVERSITY OF YORK"], "EU_Contribution": ["EUR 904 500"], "Project_Title": ["Advancing the state of the art of MIMO: the key to the successful evolution of wireless networks"], "Total_Cost": ["EUR 904 500"], "Country": ["United Kingdom", "Cyprus", "United Kingdom"], "Project_ACR": ["ATOM"], "Technology_Description": "The world is experiencing an explosion in wireless broadband usage and global wireless data traffic is expected to grow at an annual rate of 78% through 2016. Multiple-input multiple-output (MIMO) technologies have been envisioned as a key to the successful deployment of next generation networks, which are challenged by many practical constraints, such as spectrum scarcity and dynamical wireless environments. The ATOM project will set an ambitious research agenda to fully exploit the potentials of MIMO technologies for revolutionizing wireless networks. Particularly the overall objective of ATOM is to accelerate the transfer and deployment of research knowledge between European countries and third-country partners in order to provide a framework of advanced MIMO solutions for realizing green, secure and high data throughput wireless communications. The novelty of this project is four-fold. Firstly the project brings together two advanced MIMO technologies, massive MIMO and cloud radio access networks (C-RAN), where a novel heterogeneous network architecture is proposed to boost network capacity by effectively exploiting the advantages of massive MIMO and C-RAN. Secondly a rigorous algorithm-theoretic framework for maximizing energy efficiency is developed for the proposed heterogeneous architecture, where energy harvesting is realized by applying the novel concept, simultaneous wireless information and power transfer (SWIPT). Thirdly dynamic physical layer conditions in wireless environments are used to develop comprehensive security solutions for implementing keyless secure transmissions as well as key establishment, which will bridge the gap between physical layer security and the conventional cryptography. Finally we will extend the existing wireless network testbed available at the consortium and carry out experimental evaluations for closing the gap between theory and practice.", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-02-01"], "Project_ID": ["690750"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Synapse formation and maturity through planar cell polarity pathway"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["SynPCP"], "Technology_Description": "SynPCP is a MSCA-IF-EF project in Neuroscience aimed at deciphering spatiotemporal mechanisms controlled by the planar cell polarity (PCP) protein Scribble (Scrib) in spine during specification and morpho-fonctional plasticity that depend on the dynamics of the actin cytoskeleton and trans-synaptic adhesions. Growing evidences suggest that PCP signaling is fundamental for neuronal development mechanisms, including dendrite morphogenesis and synaptogenesis. PCP signaling defects have been linked to a number of human neuropathies such as autism. Because of its subcellular compartment localization and interaction with actin, we hypothesize that Scrib nanoscale organization within the spine could control cytoskeleton and/or adhesion dynamics. To address this, I plan to study the coupling or interplay between Scrib-dependent signaling and the assembly of actin cytoskeleton macromolecular complexes and its connection to cadherin-adhesion molecules using biochemistry, biophysics and 3D super-resolution optical microscopy techniques, in normal and pathological conditions. This project will provide novel conceptual insights into the nanoscale segregation of PCP proteins in spines and how individual PCP proteins control the actin cytoskeleton to build functional synapses. This project will offer a multilevel and interdisciplinary approach to understand the consequences of mutations of PCP signaling at the nanoscale, cellular and physiological levels, on the establishment, maturation and function of the basic functional unit of neuronal integration in the complex circuit of the hippocampus: the dendritic spine. SynPCP will be setup at the Bordeaux Neurocampus which is well known for its contribution to synapse development and brain function. This project offers a scientific and training program critical for my career but also for the general understanding of the molecular mechanisms underlying the normal and pathological brain.", "To": ["2020-02-29, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2018-03-01"], "Project_ID": ["750253"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["Klinikum der Universitaet Regensburg", "THE UNIVERSITY OF NOTTINGHAM", "ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI", "KAROLINSKA INSTITUTET", "FUNDACION PARA LA INVESTIGACION BIOSANITARIA DE ANDALUCIA ORIENTAL-ALEJANDRO OTERO", "UNIVERSITAET ULM", "ACADEMISCH ZIEKENHUIS GRONINGEN", "UNIVERSITEIT MAASTRICHT", "UNIVERSITAT ZURICH", "PARIS-LODRON-UNIVERSITAT SALZBURG", "UNIVERSYTET MEDYCZNY W LODZI.", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 3 823 896,60"], "Project_Title": ["European School for Interdisciplinary Tinnitus Research"], "Total_Cost": ["EUR 3 823 896,60"], "Country": ["Germany", "United Kingdom", "Italy", "Sweden", "Spain", "Germany", "Netherlands", "Netherlands", "Switzerland", "Austria", "Poland", "France"], "Project_ACR": ["ESIT"], "Technology_Description": "The European School for interdisciplinary tinnitus research (ESIT) provides an opportunity for young researchers to work on leading-edge research projects, which will radically improve the situation of 42 million European tinnitus patients. They will develop new treatment solutions for tinnitus, fundamentally improve existing treatment paradigms, implement innovative research methods, perform the first genetic studies on tinnitus and establish the largest pan-European tinnitus dataset, which will allow the implementation of innovative solutions for personalized tinnitus treatment. High quality network-wide training will prepare the individual researchers with outstanding academic as well as personal skills to perform these tasks. ", "To": ["2021-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2017-04-01"], "Project_ID": ["722046"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["IT-UNIVERSITETET I KOBENHAVN"], "EU_Contribution": ["EUR 200 194,80"], "Project_Title": ["Infrastructuring SuStainable Playbour"], "Total_Cost": ["EUR 200 194,80"], "Country": ["Denmark"], "Project_ACR": ["ISSP"], "Technology_Description": "\"This proposal relates to the sustainability of grassroots, collaborative and participative socio-technical communities to the extent that it focuses on the paradigmatic case of playbour: a concept describing \u201ca condition where play is work and work is play\u201c and referring to those collaborative and participative assemblages where the dimensions of fun and enjoyment, typical of engagement in play, blur and mix with the ones of productivity and professionalization of participation. Overarching goal of this proposal is to develop a set of guidelines and principles which would support practitioners and scholars in nurturing collaborative infrastructures that embed sustainability by (co)design. The research relies on the analytical lens of infrastructure and infrastructural inversion typical of Science and Technology Studies (STS). At the empirical level the research involves a comparative case study approach which will examine socio-technical collectives which are engaged in playbour and are in the maturity stage of their life cycle. Qualitative data gathering (participant observation and interviewing) and inductive analysis techniques (grounded theory) will be adopted for this study. The impact of this study will be relevant to the extent that European Commission is also trying to nurture and steer collaborative, grassroots and innovative initiatives (e.g. \"\"Open and Participative Innovation\"\" and \"\"Collective Awareness Platform for Sustainability and Social Innovation\u201d frames). The result of this research will also provide practical insights for the sustainability of these instances.\"", "To": ["2020-01-07, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-08"], "Project_ID": ["749353"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF LEEDS"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Shear Stress Induced Arterial and Venous Specification through Piezo1"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SAVE"], "Technology_Description": "Arteriovenous malformations (AVMs) are characterised by abnormal connections between arteries and veins due to defects during vascular remodelling. Although often asymptomatic, AVMs can cause intense pain and patients affected present higher risk for strokes and aneurysms. Hereditary AVMs have a prevalence of 18 in 100000 people causing a two-fold increase in mortality in patients younger than 60 years of age. Hereditary AVMs are linked to defective Notch/BMP signalling, however they represent less than 10% of cases. The majority of AVMs do not present genetic mutations and remain idiopathic. ", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["748369"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FORSCHUNGSVERBUND BERLIN EV"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["The genomic basis of convergent evolution in modern sloths (Xenarthra, Mammalia)"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["CONVGENOMS"], "Technology_Description": "At the end of the Pleistocene mass extinctions of the mega-fauna occurred worldwide, in particular in the Americas. Following the last glacial period, mammoths, mastodonts, giant sloths and other large mammals succumbed until extinction (about 10,000 years ago). While some Orders within Mammalia lost a couple of species, the sloths (Folivora, Xenarthra) clade has virtually lost all its diversity, gaining a status of a nearly-extinct suborder. Only two out of the close to 100 genera estimated to have existed survived to the mass extinctions to this date, named Bradypus and Choloepus. In contrast to their giant relatives, the modern sloths are medium-sized animals that developed a very specialized feature: obligatory arboreal suspensory behaviour. Their surprisingly high number of superficial similarities were acquired in parallel \u2013 since both genera are completely unrelated, and probably diverged ~30 Mya \u2013 and represent an amazing example of convergent evolution. In the current Genomics era, we are finally at a point in which full genomes can be assembled for non-model organisms at reasonable costs, bringing unprecedented opportunities for new studies on elementary questions on evolution. Here we propose to study the genomic signs of convergent evolution leading to obligatory suspensory locomotion and low metabolic rate on a comparative genomic analysis including 4 whole genome sloth sequences, three of which will be sequenced and assembled within this study. The Experienced Researcher masters all the bioinformatics expertise to complete the genomes. The host institution offers all the infrastructure and hypothesis thinking to successfully finalize the project. Jointly this team can push the boundaries of biological knowledge beyond, which will help the applicant to mature in order to lead a research group in the future. The applicant will also be trained in project management, supervision, teaching, and presentation of scientific results.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations"], "From": ["2017-10-01"], "Project_ID": ["750747"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["TECHNISCHE UNIVERSITAET DRESDEN", "TECHNISCHE UNIVERSITAET DRESDEN"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Scalable and efficient production of functionalized, high-performance solution-processable graphene-materials"], "Total_Cost": ["EUR 150 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["HIPER-G"], "Technology_Description": "The worldwide increasing need for resources and energy as well as the foreseeable depletion of fossil fuels has led scientists into a race towards finding cleaner, more efficient and sustainable technologies. Graphene is believed to be able to play a crucial role in these developments due to its outstanding properties like excellent conductivity, mechanical strength, flexibility and chemical stability. A possible large-scale application is foreseen in polymer composites, where next to increased mechanical stability, graphene can introduce additional functionalities such as conductivity, antistatic properties or flame retardancy to specialty and commodity polymers. In addition, the potential to integrate cheap graphene-based, printed sensors, actuators, or networking capabilities into every-day products opens up completely new fields of application (e.g. the Internet of Things vision). Current industrial preparation techniques are available to provide graphene at large scale but the materials suffer from drawbacks in terms of processability, which is why despite the great potential, only a very limited number of graphene-enhanced products are available on the market. Recently, we were able to demonstrate a novel technology for the functionalization of graphene. With this approach, we are now focusing to produce functionalized graphene with tailorable properties and improved processability. This breakthrough will open up new possibilities and prospects for the application of graphene. To exploit the potential impact of this approach we are aiming to prove the usability of our functionalized graphene in different applications in cooperation with experienced partners from industry.", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["768930"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI VERONA", "UNIVERSITA DEGLI STUDI DI VERONA"], "EU_Contribution": ["EUR 2 750 000"], "Project_Title": ["Autonomous Robotic Surgery"], "Total_Cost": ["EUR 2 750 000"], "Country": ["Italy", "Italy"], "Project_ACR": ["ARS"], "Technology_Description": "The goal of the ARS project is the derivation of a unified framework for the autonomous execution of robotic tasks in challenging environments in which accurate performance and safety are of paramount importance. We have chosen surgery as the research scenario because of its importance, its intrinsic challenges, and the presence of three factors that make this project feasible and timely. In fact, we have recently concluded the I-SUR project demonstrating the feasibility of autonomous surgical actions, we have access to the first big data made available to researchers of clinical robotic surgeries, and we will be able to demonstrate the project results on the high performance surgical robot \u201cda Vinci Research Kit\u201d. The impact of autonomous robots on the workforce is a current subject of discussion, but surgical autonomy will be welcome by the medical personnel, e.g. to carry out simple intervention steps, react faster to unexpected events, or monitor the insurgence of fatigue. The framework for autonomous robotic surgery will include five main research objectives. The first will address the analysis of robotic surgery data set to extract action and knowledge models of the intervention. The second objective will focus on planning, which will consist of instantiating the intervention models to a patient specific anatomy. The third objective will address the design of the hybrid controllers for the discrete and continuous parts of the intervention. The fourth research objective will focus on real time reasoning to assess the intervention state and the overall surgical situation. Finally, the last research objective will address the verification, validation and benchmark of the autonomous surgical robotic capabilities. The research results to be achieved by ARS will contribute to paving the way towards enhancing autonomy and operational capabilities of service robots, with the ambitious goal of bridging the gap between robotic and human task execution capability.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["742671"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET", "UNIVERSITE DES SCIENCES ET TECHNOLOGIES DE LILLE - LILLE I", "UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II.", "UNIVERSITY OF YORK", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "DEVRO PLC"], "EU_Contribution": ["EUR 2 186 974,80"], "Project_Title": ["Teaching Emerging Methods in Palaeoproteomics for the European Research Area"], "Total_Cost": ["EUR 2 186 974,80"], "Country": ["Denmark", "France", "Italy", "United Kingdom", "Germany", "United Kingdom"], "Project_ACR": ["TEMPERA"], "Technology_Description": "TEMPERA will provide international, intersectoral and interdisciplinary state-of-the-art doctoral training to prepare the next generation of specialists in mass spectrometry-based ancient protein residues analysis for biomolecular diagnostics and conservation of cultural heritage material.", "To": ["2021-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-03-01"], "Project_ID": ["722606"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["FORSCHUNGSVERBUND BERLIN EV", "FORSCHUNGSVERBUND BERLIN EV"], "EU_Contribution": ["EUR 2 499 991"], "Project_Title": ["Volume regulation and extracellular signalling by anion channels"], "Total_Cost": ["EUR 2 499 991"], "Country": ["Germany", "Germany"], "Project_ACR": ["VOLSIGNAL"], "Technology_Description": "Cells must regulate their volume in response to changes in osmolarity and during cell division, migration, apoptosis, and transepithelial transport. Regulated membrane transport of ions and metabolites creates osmotic gradients that secondarily drive water across the membrane. Organic \u2018osmolytes\u2019 such as glutamate also serve in extracellular signalling and volume-regulatory ion transporters are often used for other purposes, putting volume regulation into the context of diverse organismal functions. ", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-10-01"], "Project_ID": ["740537"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["FREIE UNIVERSITAET BERLIN", "FREIE UNIVERSITAET BERLIN"], "EU_Contribution": ["EUR 2 435 113"], "Project_Title": ["The Arabic Anonymous in a World Classic"], "Total_Cost": ["EUR 2 435 113,77"], "Country": ["Germany", "Germany"], "Project_ACR": ["AnonymClassic"], "Technology_Description": "AnonymClassic is the first ever comprehensive study of Kalila and Dimna (a book of wisdom in fable form), a text of premodern world literature. Its spread is comparable to that of the Bible, except that it passed from Hinduism and Buddhism via Islam to Christianity. Its Arabic version, produced in the 8th century, when this was the lingua franca of the Near East, became the source of all further translations up to the 19th century. The work\u2019s multilingual history involving circa forty languages has never been systematically studied. The absence of available research has made world literature ignore it, while scholars of Arabic avoided it because of its widely diverging manuscripts, so that the actual shape of the Arabic key version is still in need of investigation. AnonymClassic tests a number of \u2018high-risk\u2019 propositions, including three key hypotheses: 1) The anonymous Arabic copyists of Kalila and Dimna are de facto co-authors, 2) their agency is comparable to that of the named medieval translators, and 3) the fluctuation of the Arabic versions is conditioned by the work\u2019s fictional status. AnonymClassic\u2019s methodology relies on a cross-lingual narratological analysis of the Arabic versions and all medieval translations (supported by a synoptic digital edition), which takes precisely the interventions at each stage of transmission (redaction, translation) as its subject. Considering the work\u2019s paths of dissemination from India to Europe, AnonymClassic will challenge the prevalent Western theoretical lens on world literature conceived \u2018from above\u2019 with the view \u2018from below,\u2019 based on the attested cross-cultural network constituted by its versions. AnonymClassic will introduce a new paradigm of an East-Western literary continuum with Arabic as a cultural bridge. Against the current background of Europe\u2019s diversifying and multicultural society, AnonymClassic purposes to integrate pre-modern Near Eastern literature and culture into our understanding of Global Culture.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["742635"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["BEYOND THE CODE: SUSTAINABILITY IN OPEN SOURCE"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["BEYOND-CODE"], "Technology_Description": "Open Source (OS) software is particular in that it can be accessed and modified openly. Originating from technological labs, OS is now ubiquitous and a major part of the EU's economy. Some estimate it to be 450 billions per year (EUR). The increasing ubiquity of OS has turned it into a configuration of social and societal elements such as the decentralised ownership of projects or meeting needs that traditional markets cannot. The socio-technical configurations of OS are not evident, perhaps not even intended. The various meanings of sustainability enact how OS ideas are created and travel beyond their original birthing place, but have, as yet, mainly received a rational/economic focus. This project proposes to explore OS as it travels beyond its designing communities and, in so doing, re-functions the meaning of sociological sustainability that hold it in place. ", "To": ["2019-09-15, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-09-16"], "Project_ID": ["744957"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN", "THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN"], "EU_Contribution": ["EUR 1 999 998"], "Project_Title": ["From Typhoid Fever to Antimicrobial Mechanisms"], "Total_Cost": ["EUR 1 999 998"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["TYPHI"], "Technology_Description": "This programme will identify critical host mechanisms that kill bacterial pathogens by exploring a novel mammalian antimicrobial pathway, which I discovered. This pathway protects non-susceptible hosts from typhoid fever. Typhoid fever is caused by Salmonella Typhi, a unique intracellular pathogen that kills more than 200,000 humans per year. Yet, Salmonella Typhi does not infect other mammalian species, such as mice. An understanding of the mechanisms that protect mice from Salmonella Typhi infection will enable me to determine how Salmonella Typhi circumvents these protective mechanisms in humans to cause fatal disease. I have demonstrated that the mechanisms protecting mice are based on an intracellular trafficking process regulated by the Rab32 GTPase. The following critical questions will be addressed:", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["726152"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITE DE FRIBOURG", "UNIVERSITE DE FRIBOURG"], "EU_Contribution": ["EUR 2 495 930"], "Project_Title": ["Locus Ludi: The Cultural Fabric of Play and Games in Classical Antiquity"], "Total_Cost": ["EUR 2 495 930"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["Locus Ludi"], "Technology_Description": "Play and games were ubiquitous in antiquity, among free men and slaves, men and women, adults and children, in town and country. Even gods played. Ludic culture created communities from early childhood to a ripe old age. Did these groups play together, or did they play different games, with distinct rules? And did they play similar games to us? This interdisciplinary project will provide the first comprehensive study of the evidence. Written, archaeological and iconographic sources are abundant, but forgotten in museums and libraries. This neglect is due to the modern Western view of games as children\u2019s pastime, if not a waste of time. Ancient play and games reflect the gendered, religious, economic, and political fabric of a society, as much as they shape the lives of players by transmitting a cultural identity and an intangible heritage. Ludic culture evolves over time and this project intends to provide a benchmark by reconstructing this history in the Greek world, from the birth of the city-state, c. 800 BCE, to the Roman conquest in 146 BCE, and in the Roman world from the Republican age, c. 500 BCE, to the end of the Western Roman Empire, c. 500 CE. ", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["741520"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW", "INSTITUT NATIONAL D'ETUDES DEMOGRAPHIQUES", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "HUNGARIAN CENTRAL STATISTICAL OFFICE DEMOGRAPHIC RESEARCH INSTITUTE", "SZKOLA GLOWNA HANDLOWA W WARSZAWIE", "UNIVERSITEIT UTRECHT", "BUNDESINSTITUT FUR BEVOLKERUNGSFORSCHUNG", "UNIVERSITA COMMERCIALE LUIGI BOCCONI"], "EU_Contribution": ["EUR 1 996 667,50"], "Project_Title": ["Generations and Gender Programme: Evaluate, Plan, Initiate"], "Total_Cost": ["EUR 1 996 667,50"], "Country": ["Netherlands", "France", "Germany", "Hungary", "Poland", "Netherlands", "Germany", "Italy"], "Project_ACR": ["GGP-EPI"], "Technology_Description": "The Generations and Gender Programme (GGP) provides high quality cross-national, longitudinal data for the study of population change. The data provided by the GGP have been used by more than 3,000 researchers worldwide and have led to over 500 peer-reviewed journal articles. The data have provided insights into some of the most pressing societal challenges such as care for older persons, female employment, inequality, social exclusion, social mobility and migration. The overall objective of GGP-EPI is to bring the GGP to the level of maturity required for inclusion as an active project on the 2020 ESFRI Roadmap and eventually for its full implementation as a distributed research infrastructure. Specifically, the project sets out to \u2018Evaluate, Plan and Initiate\u2019 the GGP\u2019s transition to a distributed research infrastructure through a series of activities which will strengthen all aspects of the project from its fieldwork operations through to its long term financing and governance. This includes: (1) To evaluate the GGP\u2019s governance and management structure and to identify the governance, financial, and legal model that will best serve the GGP and its various stakeholders; (2) To plan for the recent and foreseeable technological and data developments and identify the e-needs of the GGP; and (3) To initiate the centralization of the GGP\u2019s operations throughout its data life cycle and especially in connection with new data collection. In doing so, the GGP will strengthen its position in the European Research Area, and will deliver innovative, cutting edge data on population change for researchers and policy makers.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["INFRADEV-02-2016 - Preparatory Phase and support to early phase of ESFRI projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Netherlands"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["739511"], "Call_for_Proposal": ["H2020-INFRADEV-2016-2"]}, -{"Partners": ["Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich"], "EU_Contribution": ["EUR 2 500 000"], "Project_Title": ["In Vivo Single-Cell Mechanomics of Bone Adaptation and Regeneration in the Aging Mouse"], "Total_Cost": ["EUR 2 500 000"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["MechAGE"], "Technology_Description": "Osteoporosis, one of the most prevalent degenerative diseases, is characterized by a reduction in bone mass and increased fracture risk and has been partly attributed to the decrease in mechanical usage of the skeleton. A detailed understanding of the molecular mechanisms governing load-regulated bone remodeling could therefore lead to the identification of molecular targets for the development of novel therapies. Bone remodeling is a multiscale process mediated through complex interactions between multiple cell types and their local 3D environments. However, the underlying mechanisms of how cells respond to mechanical signals are still unclear. By combining single-cell \u201comics\u201d technologies with well-established tissue-scale models of bone mechanobiology, MechAGE proposes to develop the technology required to allow spatially resolved in vivo single-cell mechanomics of bone adaptation and regeneration. CRISPR/Cas technology will be exploited to generate fluorescent reporter mice to identify the different cell types involved in the bone remodeling process. By combining RNA-sequencing of single cells isolated by laser-capture microdissection with micro-finite element analysis and time-lapsed in vivo micro-CT, MechAGE will link the transcriptome of hundreds of single cells to their local mechanical in vivo environment (LivE). This will allow investigation of molecular responses of the cells to LivE changes with aging in established mouse models of bone adaptation and regeneration. In addition to in vivo mechanomics, MechAGE proposes to use cellular and multiscale computational modeling to run in silico simulations of real-world events for better understanding of diseases of aging in mice and to maximize the use of the high quality in vivo mechanomic data. Findings from MechAGE will lead to a systems level understanding of the spatio-temporal regulation of gene expression during the process of load-induced bone adaptation and regeneration in the aging mouse.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["741883"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITAT ZURICH", "UNIVERSITAT ZURICH", "UNIVERSITAET BASEL"], "EU_Contribution": ["EUR 1 499 925"], "Project_Title": ["Spin-Delocalization with a Twist: Chiral Open-Shell Helices"], "Total_Cost": ["EUR 1 499 925"], "Country": ["Switzerland", "Switzerland", "Switzerland"], "Project_ACR": ["INSPIRAL"], "Technology_Description": "Spin-delocalization in molecules containing unpaired electrons gives rise to an unusual intermolecular interaction, named as pancake bond. This bonding interaction couples unpaired electrons between multiple pairs of atoms from each face-to-face oriented spin units, such as phenalenyl radical, and abets formation of assemblies that display large antiferromagnetic interaction in the solid state. This phenomenon governs the potential use of such spin systems as molecular conductors, magneto-optical bistable materials, or molecular spin batteries. Formation of such assemblies during crystallization is spontaneous. It is therefore difficult to control and tune the antiferromagnetic interaction, which dictates the electronic properties of the solid material. Inspired by this challenge, the goal of this project is to develop systems, where the spin-interaction can be tuned within a single molecule to understand principles that govern an intermolecular assembly in the solid state and the bulk properties.", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["716139"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "KOBENHAVNS UNIVERSITET", "UNIVERSITA DEGLI STUDI DI CAMERINO", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "IBM RESEARCH GMBH", "STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN", "UNIVERSITA TA MALTA", "AALTO-KORKEAKOULUSAATIO", "UNIVERSITAT KONSTANZ", "UNIVERSITEIT GENT", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "THALES SA", "TECHNISCHE UNIVERSITEIT DELFT", "Institute of Science and Technology Austria", "HITACHI EUROPE LIMITED", "STMICROELECTRONICS SRL", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 10 000 000"], "Project_Title": ["Hybrid Optomechanical Technologies"], "Total_Cost": ["EUR 10 000 000"], "Country": ["Switzerland", "Denmark", "Italy", "United Kingdom", "Switzerland", "Netherlands", "Malta", "Finland", "Germany", "Belgium", "France", "France", "Netherlands", "Austria", "United Kingdom", "Italy", "Germany"], "Project_ACR": ["HOT"], "Technology_Description": "The hybrid optomechanical technologies (HOT) consortium will lay the foundation for a new generation of devices, which connect, or indeed contain, several platforms at the nanoscale in a single \u201chybrid\u201d system. As hybrid interfaces they will allow to harness the unique advantages of each subsystem within a nano-scale footprint, while as integrated hybrid devices they will enable entirely novel functionalities. A particular focus will be on nano-optomechanical devices that comprise electrical, microwave or optical systems with micro- and nano-mechanical systems. Research in the past decade, in particular by European groups, has shown the significant technological potential that such nano-optomechanical systems can offer, in particular by establishing a new way in which optical, radio-frequency and microwave signals can be interfaced. The present consortium includes leading academic groups and industrial partners to explore the potential of these hybrid-nano-optomechanical systems. It will explore hybrid opto- and electro-mechanical devices operating at the physical limit for conversion, synthesis, processing, sensing and measurement of EM fields, comprising radio, microwave frequencies to the terahertz domain. These spectral domains open realistic applications in the existing application domains of medical (e.g. MRI imaging), security (e.g. Radar and THz monitoring), positioning, timing and navigations (Oscillators) and for future quantum technology. The research aims at specific technological application, with realistic operating conditions and seeks to develop actual system demonstrators. In addition, it will explore how these hybrid transducers can be fabricated within standard CMOS processing, and thereby be made compatible with current manufacturing methods. The HOT devices will thereby impact today\u2019s technology and likewise address potential future need for the manipulation of quantum signals.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["FETPROACT-01-2016 - FET Proactive: emerging themes and communities"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-01-01"], "Project_ID": ["732894"], "Call_for_Proposal": ["FETPROACT-2016"]}, -{"Partners": ["FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "JOHANNES GUTENBERG-UNIVERSITAT MAINZ", "THE UNIVERSITY OF EXETER", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "PHOTEK LIMITED", "PANEPISTIMIO KRITIS"], "EU_Contribution": ["EUR 3 999 250"], "Project_Title": ["Ultrasensitive chiral detection by signal-reversing cavity polarimetry: applications to in-situ proteomics, single-molecule chirality, HPLC analysis, medical diagnostics, and atmospheric studies"], "Total_Cost": ["EUR 3 999 250"], "Country": ["Greece", "Switzerland", "United Kingdom", "Germany", "United Kingdom", "Germany", "United Kingdom", "Greece"], "Project_ACR": ["ULTRACHIRAL"], "Technology_Description": "Chirality is a fundamental property of life, making chiral sensing and analysis crucial to numerous scientific subfields of biology, chemistry, and medicine, and to the pharmaceutical, chemical, cosmetic, and food industries, constituting a market of 10s of billion \u20ac, and growing.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-01-2016-2017 - FET-Open research and innovation actions"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Greece"], "Activity": ["Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["737071"], "Call_for_Proposal": ["H2020-FETOPEN-1-2016-2017"]}, -{"Partners": ["Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "CARLSBERG AS", "DEUTSCHE SAATVEREDELUNG AG", "BASECLEAR BV", "AGROISOLAB GMBH", "HELIOSPECTRA AB", "LEMNATEC GMBH", "NPZ INNOVATION GMBH", "UNIVERSITAT ZURICH", "UNIVERSITAET BASEL"], "EU_Contribution": ["EUR 2 617 989,18"], "Project_Title": ["PlantHUB - Boosting technology transfer and responsible research and innovation (RRI) in plant sciences"], "Total_Cost": ["EUR 2 617 989,18"], "Country": ["Switzerland", "Denmark", "Germany", "Netherlands", "Germany", "Sweden", "Germany", "Germany", "Switzerland", "Switzerland"], "Project_ACR": ["PlantHUB"], "Technology_Description": "In PlantHUB will capture the academic, industrial and regulatory expertise from 5 world-class universities, 1 public research organisation, 1 governmental organization, 8 enterprises including 5 SMEs to train 10 ESRs in skills and competencies necessary to apply responsible research and innovation (RRI) in the area of plant breeding and production. We wish to address the demand of RRI leadership in plant science related research and diffusion of innovation. The individual research projects are demand-driven, responding to the needs of companies - particular SMEs - to increase R&I capacities. The outcomes are new molecular tools for plant breeding, new forage, cereal and oil crop varieties, non-invasive imaging and phenotyping technologies, intelligent lighting systems for plant growth, new software and services for complex genomic analyses, and plant product quality. PlantHUB industrial doctoral programme is ground-breaking in a number of respects: (i) doctoral training is placed into an entrepreneurial environment of leading public and private organisations (ii) it combines practical hands-on R&D and technology transfer in plant breeding and production with RRI training and practise. On completion of the training, graduates will have deep interdisciplinary knowledge of plant breeding, crop improvement, high-throughput technologies, isotope and big data analysis. In combination with a portfolio of transferable skills they will be able to take a lead in stakeholder & public engagement, innovation management, technology transfer and entrepreneurship. Our programme will become a flagship example at the forefront of intersectoral research, underpinned with a carefully created training curriculum to foster awareness, know-how, expertise and competence in RRI.", "To": ["2020-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-12-01"], "Project_ID": ["722338"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["UNIVERSITE DE LIMOGES", "INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON", "UNIVERSITE DE VALENCIENNES ET DU HAINAUT-CAMBRESIS", "FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG", "BUNDESANSTALT FUER MATERIALFORSCHUNG UND -PRUEFUNG", "UNIVERSITA DEGLI STUDI DI PADOVA", "POLITECNICO DI TORINO", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "UNIVERSITAT POLITECNICA DE CATALUNYA", "CENTRE DE RECHERCHES DE L'INDUSTRIEBELGE DE LA CERAMIQUE ASBL", "3DCERAM", "SAINT-GOBAIN CENTRE DE RECHERCHES ET D'ETUDES EUROPEEN", "NORAKER", "ANTHOGYR SAS", "ROBERT BOSCH GMBH", "H.C. STARCK CERAMICS GMBH", "DESAMANERA SRL", "UNIVERSITE MOHAMMED V DE RABAT"], "EU_Contribution": ["EUR 877 500"], "Project_Title": ["Additive Manufacturing Initiative for Transnational Innovation in Europe"], "Total_Cost": ["EUR 877 500"], "Country": ["France", "France", "France", "Germany", "Germany", "Italy", "Italy", "United Kingdom", "Spain", "Belgium", "France", "France", "France", "France", "Germany", "Germany", "Italy", "Morocco"], "Project_ACR": ["AMITIE"], "Technology_Description": "Additive manufacturing (AM) technologies and overall numerical fabrication methods have been recognized by stakeholders as the next industrial revolution bringing customers\u2019 needs and suppliers\u2019 offers closer. It cannot be dissociated to the present trends in increased virtualization, cloud approaches and collaborative developments (i.e. sharing of resources). AM is likely to be one good option paving the way to Europe re-industrialization and increased competitiveness. AMITIE will reinforce European capacities in the AM field applied to ceramic-based products. ", "To": ["2021-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2017-03-01"], "Project_ID": ["734342"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["UNIVERSITE DU MANS", "UNIVERSITE DE NANTES", "CARDIFF UNIVERSITY", "PANEPISTIMIO KRITIS", "UNIWERSYTET SZCZECINSKI", "KOBENHAVNS UNIVERSITET", "FUNDACION CANARIA PARQUE CIENTIFICO TECNOLOGICO DE LA UNIVERSIDAD DE LAS PALMAS DE GRAN CANARIA", "ZURCHER HOCHSCHULE FUR ANGEWANDTE WISSENSCHAFTEN", "MICROPHYT", "INSTITUTO TECNOLOGICO DE CANARIAS, S.A.", "INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER", "UNIVERSITE D ORAN", "UNIVERSITAS BRAWIDJAJA", "UNIVERSITAS PAJAJARAN", "TRUONG DAI HOC SAI GON", "UNIVERSITAS TANJUNGPURA", "UNIVERSITE LAVAL", "UNIVERSITE DU QUEBEC A RIMOUSKI", "MOUNT ALLISON UNIVERSITY", "MIDDLE TENNESSEE STATE UNIVERSITY", "THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK", "UNIVERSITY OF TASMANIA"], "EU_Contribution": ["EUR 1 602 000"], "Project_Title": ["The Genus Haslea, New marine resources for blue biotechnology and Aquaculture"], "Total_Cost": ["EUR 1 602 000"], "Country": ["France", "France", "United Kingdom", "Greece", "Poland", "Denmark", "Spain", "Switzerland", "France", "Spain", "France", "Algeria", "Indonesia", "Indonesia", "Vietnam", "Indonesia", "Canada", "Canada", "Canada", "United States", "United States", "Australia"], "Project_ACR": ["GHaNA"], "Technology_Description": "The GHaNA project aims to explore and characterize a new marine bioresource, for blue biotechnology applications in aquaculture, cosmetics and possibly food and health industry. The project will determine the biological and chemical diversity of Haslea diatoms to develop mass-scale production for viable industrial applications by maximising biomass production and associated high-value compound production, including terpenoids, marennine-like pigments, lipids and silica skeletons. The genus Haslea species type H. ostrearia, produces marennine, a water-soluble blue pigment used for greening oysters in Western France, which is also a bioactive molecule. Haslea diatoms have thus a high potential for use in (1) existing oyster farming, (2) production of pigments and bioactive compounds with natural antibacterial properties, (3) application as a colouring agent within industry, and (4) use of silica skeletons as inorganic \u201cbiocharges\u201d in the formulation of new elastomeric materials. This will be achieved through fundamental and applied-oriented research to isolate fast- growing strains of Haslea, optimising their growth environment to increase marennine and other high-value compound productivity; to develop blue biotechnology specifically applied to benthic microalgae (biorefinery approach, processes); and to develop industrial exploitation of colouring and bioactive compounds through commercial activities of aquaculture, food, cosmetics and health.", "To": ["2021-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other", "Higher or Secondary Education Establishments"], "From": ["2017-03-01"], "Project_ID": ["734708"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["STICHTING WAGENINGEN RESEARCH", "THE QUEEN'S UNIVERSITY OF BELFAST", "VYSOKA SKOLA CHEMICKO-TECHNOLOGICKA V PRAZE", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "LINKOPINGS UNIVERSITET", "AQUAMARIJN MICRO FILTRATION BV", "CSEM CENTRE SUISSE D'ELECTRONIQUE ET DE MICROTECHNIQUE SA - RECHERCHE ET DEVELOPPEMENT"], "EU_Contribution": ["EUR 2 843 040,96"], "Project_Title": ["Smartphone analyzers for on-site testing of food quality and safety"], "Total_Cost": ["EUR 2 843 040,96"], "Country": ["Netherlands", "United Kingdom", "Czech Republic", "Spain", "Sweden", "Netherlands", "Switzerland"], "Project_ACR": ["FoodSmartphone"], "Technology_Description": "Current food quality and safety testing is, to a large extent, an inefficient, expensive and ineffective process, unable to assure food safety for all consumers and unable to prevent major food fraud incidents. A paradigm shift in quality and safety testing is urgently required in order to free resources for an intensified combat against fraud in the food chain. As an enabling technology solution, the FoodSmartphone ETN proposes the development of smartphone-based (bio)analytical sensing and diagnostics tools for simplified on-site rapid pre-screening of food quality and safety parameters and wireless data transfer to servers of relevant stakeholders. FoodSmartphone comprises 7 Training Sites (3 universities, 3 research centres, 1 innovation SME), plus 2 Partner Organisations (1 global food industry and 1 diagnostics SME). The consortium has been built upon highly complementary disciplines: (bio)analytical chemists, biologists, physicists, micro-engineers, mathematicians and food chemists will work together on the joint supra-disciplinary goal. FoodSmartphone provides a unique mix of exciting local PhD research covering all aspects of smartphone-based screening tools plus a wealth of network-wide science & innovation and transferable skills training: the ETN provides more than 14 network-wide and transferable skills training events and 16 optional- and 11 mandatory intersectoral secondment opportunities. The ETN and results thereof will be widely disseminated to key stakeholders, embedded in continuous education programs and translated into a final exploitation plan. Scientific awareness of the next generation and public engagement will be boosted by several well-targeted outreach activities. The scientific training in novel smartphone-based sensing technologies plus the complementary skills training provided will have a major impact on future EU monitoring practices and, moreover, pave the road for Citizen Science approaches to food quality and safety testing.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Netherlands"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations"], "From": ["2017-01-01"], "Project_ID": ["720325"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["SYDDANSK UNIVERSITET", "SYDDANSK UNIVERSITET", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 344 497,50"], "Project_Title": ["Transgenerational regulation of glucose metabolism by noncoding RNAs"], "Total_Cost": ["EUR 1 344 497,50"], "Country": ["Denmark", "Denmark", "Germany"], "Project_ACR": ["TransGen RNA"], "Technology_Description": "Obesity and T2D affect large populations and cause a decline in life expectancy if untreated. The pandemic proportion of obesity and inaptitude of anti-obesity approaches reflect our limited understanding of its complex environmental and genetic etiology. Genome-wide association studies revealed that disease-associated risk variants are often situated in those 98% of the genome not encoding for proteins. This noncoding genomic space yet does not reflect \u2018Junk DNA\u2019 but gives rise to >10,000 noncoding RNAs like microRNAs and long, noncoding RNAs (lncRNAs) that implicated in control of glucose metabolism and energy homeostasis also by the applicant (Kornfeld et al. Nature 2013). ", "To": ["2021-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2016-05-01"], "Project_ID": ["675014"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 499 923"], "Project_Title": ["Genetic Mapping of Evolutionary Developmental Variation using Hybrid Mouse in vitro Crosses"], "Total_Cost": ["EUR 1 499 923"], "Country": ["Germany", "Germany"], "Project_ACR": ["HybridMiX"], "Technology_Description": "Discovering the genetic changes underlying species differences is a central goal in evolutionary genetics. Most evolutionarily important traits affecting fitness are complex or quantitative traits, whose genetic bases are elusive. In mammals, dissecting the genetic basis of complex trait variation is particularly challenging, because efficient genetic mapping requires enormous pedigrees or specialized genetic panels that are typically beyond the resources of individual groups. Using a radically novel method to circumvent breeding limitations by \u201cbreeding\u201d mice in vitro, I propose to dissect the genetic basis of evolutionary developmental variation. This ground-breaking approach will allow me to create large genetic mapping panels of potentially any size from mouse interspecific hybrids of increasing evolutionary divergence. In vitro crosses promise a breakthrough in evolutionary biology: by bypassing hybrid sterility and inviability, we will ask which genetic changes underlie species differences. The proposed experiments address how genetic changes accumulate during evolution of new species to shape gene regulatory networks and cause phenotypic changes at the gene expression, fitness and organismal level. This research has the potential to revolutionize genetic mapping. If realized, its impact on personalized medicine, agricultural science and evolutionary research cannot be understated.", "To": ["2020-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2015-08-01"], "Project_ID": ["639096"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "THE REGENTS OF THE UNIVERSITY OF CALIFORNIA"], "EU_Contribution": ["EUR 257 860,80"], "Project_Title": ["Fuse smFRET and modeling to a new structural biology method and solve the functional ESCRT assembly structure"], "Total_Cost": ["EUR 257 860,80"], "Country": ["Germany", "United States"], "Project_ACR": ["smSTRUCT"], "Technology_Description": "We seek to develop a new structural biology method that is able to overcome barriers to solving very complex functional protein assemblies that are variable enough in their composition and conformation to defeat current methodologies. ", "To": ["2018-12-31, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["659446"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITAT ZURICH", "UNIVERSITAT ZURICH"], "EU_Contribution": ["EUR 2 124 965"], "Project_Title": ["Control and measurement of single macromolecules in space and time"], "Total_Cost": ["EUR 2 124 965"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["COSMOS"], "Technology_Description": "The desire to \u201cfreely suspend the constituents of matter\u201d in order to study their behaviour can be traced back over 200 years to Lichtenberg\u2019s diaries. From radio-frequency ion traps to optical tweezing of colloidal particles, existing methods to trap matter in free space or solution rely on the use of external fields that often strongly perturb the integrity of a macromolecule in solution. Recently, I invented the \u2018electrostatic fluidic trap\u2019, a \u201cfield-free\u201d principle that supports stable, non-destructive confinement of single macromolecules in room temperature fluids, representing a paradigm shift in a nearly century-old field. The spatio-temporal dynamics of a single electrostatically trapped molecule reveals fundamental information on its properties, e.g., size and electrical charge. The charge of a macromolecule is in turn a strong function of its 3D conformation - the molecular basis of biological function. I now aim to develop a new platform to study 3D macromolecular structure and temporal conformation by measuring the electrical charge of a single trapped molecule in real time, using both optical microscopy and electrical detection. Beyond the conformational dynamics of a single molecule, we will also examine interactions between two or more molecules, and the detection of minute structural differences between closely related molecular isoforms. We will further develop a novel approach to electrical transport measurements on single molecules aimed at generating for the first time a catalog of \u2018electrical signatures\u2019 for biomolecules in solution. The ability to experimentally link electrical charge and molecular structure will not only open up a new physical dimension in our understanding of macromolecules, but also advance the development of ultrasensitive, high-throughput molecular sensors for biomedical detection and analytics, potentially enabling an optical or electrical \u201csingle-snapshot\u201d read-out of the proteome or transcriptome of a single cell.", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["724180"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET", "KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 149 956"], "Project_Title": ["Electromagnetic to Optics Transducer"], "Total_Cost": ["EUR 149 956"], "Country": ["Denmark", "Denmark"], "Project_ACR": ["EMOT"], "Technology_Description": "Modern communication and sensing is done with radio- and microwaves on the one hand, and with optical fiber links, on the other. Radio- and microwaves are widely used in commercial and personal communication, as well as in sensing in, for example, medical diagnostics. Optical communication dominates long distance, point-to-point connections, such as internet. This action aims at the development of a miniature device for efficient conversion between these technological platforms. Within the AdG INTERFACE we have developed a novel principle for the opto-electromechnical transducer (Nature, 2014) and filed a US patent. We have further made progress in developing an integrated version of the transducer with enhanced sensitivity. Preliminary market analysis has shown high potential of our device in diverse areas, such as industrial internet of things, airborne intracommunication systems, scientific sensors, measurement instrumentation, radio astronomy, and nuclear magnetic spectroscopy. This action will include the first tests of the device in a flagship application relevant to NMR spectroscopy\u2014a real life MRI scanner\u2014and an extensive effort towards producing a packaged, fiber-coupled, ultralow-noise transducer ready for field demonstrations.", "To": ["2019-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["768491"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 2 212 500"], "Project_Title": ["Systems Neuroscience of Metabolism"], "Total_Cost": ["EUR 2 212 500"], "Country": ["Germany", "Germany"], "Project_ACR": ["SYNEME"], "Technology_Description": "Proopiomelanocortin (POMC)- and Agouti-Related Peptide (AgRP)-expressing, i.e. melanocortin neurons in the hypothalamus, are key regulators of feeding behaviour, glucose metabolism, autonomic responses and higher cognitive functions. They represent targets for fuel-sensing hormones like leptin and insulin that thereby control key processes in systemic energy and glucose homeostasis. Importantly, resistance to these fuel-sensing signals is known to contribute to the current obesity and diabetes epidemic. Consequently, altered POMC- and AgRP-neuron regulation in obesity contributes to the development of numerous metabolic alterations. Although the melanocortin neurons as central regulators of metabolism have been classified according to the expression of their characteristic neuropeptides, it has only recently become clear that even within these populations they represent distinct heterogeneous neurons with respect to their physiological regulation and the biological responses governed by their specific downstream neurocircuits. However, the molecular nature of heterogeneous POMC and AgRP neuron populations, their specific neurocircuitry architecture and their specific functions still remain largely unexplored. Therefore, we will employ a wide array of state-of-the-art molecular systems neuroscience and modern mouse genetics approaches to define (1) the anatomical distribution, (2) molecular signature, (3) neurocircuitry architecture, (4) regulatory principles, (5) specific biological functions, and finally (6) novel druggable regulators of these specific POMC and AgRP microcircuits. We anticipate that the new knowledge generated will not only provide novel insights into the fundamental principles of CNS-dependent control of metabolism but could also lead to targeting these specific neurocircuits to develop novel, specific, tailor-made therapies for diverse aspects of metabolic diseases for which currently only insufficient treatment options are available.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-10-01"], "Project_ID": ["742106"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["STICHTING KATHOLIEKE UNIVERSITEIT", "STICHTING KATHOLIEKE UNIVERSITEIT"], "EU_Contribution": ["EUR 1 978 194"], "Project_Title": ["Characterizing neural mechanisms underlying the efficiency of naturalistic human vision"], "Total_Cost": ["EUR 1 978 194"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["NATVIS"], "Technology_Description": "Our daily-life visual environments, such as city streets and living rooms, contain a multitude of objects. Out of this overwhelming amount of sensory information, our brains must efficiently select those objects that are relevant for current goals, such as cars when crossing a street. The visual system has developed and evolved to optimally perform tasks like these, as reflected in the remarkable efficiency of naturalistic object detection. Little is known about the neural mechanisms underlying this efficiency. NATVIS aims to fill this gap, presenting a comprehensive multi-method and hypothesis-driven approach to improve our understanding of the neural mechanisms underlying the efficient detection of objects in natural scenes. fMRI, MEG, and TMS will be used to study the neural basis of rapid attentional guidance based on scene context and episodic memory, resulting in a full characterization of when, where, and how context- and memory-based expectations interact with attentional templates in visual cortex and beyond. The powerful effects of scene context on object recognition will be studied by testing how context-disambiguated objects are represented in visual cortex, characterizing when context-based predictions bias object processing, and testing for causal interactions between scene- and object-selective pathways in visual cortex. NATVIS will study how the brain uses real-world regularities to support object grouping and reduce clutter in scenes, modelling the cortical representation and neural dynamics of multiple simultaneously presented objects as a function of positional regularity. Finally, advanced multivariate modelling of fMRI data will test the functional relevance and representational content of internally generated templates that are hypothesized to facilitate object detection in scenes. This program of research tackles the next frontier in the neuroscience of high-level vision and attention, embracing the complexity of naturalistic vision.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["725970"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 149 563"], "Project_Title": ["A new tool in drug development: mapping of compound-protein interaction using forward genetics"], "Total_Cost": ["EUR 149 563"], "Country": ["Germany", "Germany"], "Project_ACR": ["ACUSLABS"], "Technology_Description": "Development of new medicines such as chemotherapeutic drugs requires a detailed understanding of their biological mechanism of action. What are the desired and undesired interactions with biological molecules? It is our goal to found a start-up company that will provide a solution to this challenge. Using novel and ground-breaking approaches we can identify target structures and interaction partners of small bioactive molecules at an unmatched and unprecedented resolution. ERC PoC funding will be essential to support our activities to identify optimal strategies and initial customers for our service.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-07-01"], "Project_ID": ["768524"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET", "KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 1 339 600"], "Project_Title": ["Hybrid Epitaxial Materials for Novel Quantum State Detection and Manipulation"], "Total_Cost": ["EUR 1 339 600"], "Country": ["Denmark", "Denmark"], "Project_ACR": ["HEMs-DAM"], "Technology_Description": "Research in quantum information technologies is receiving increasing attention worldwide, and huge efforts are put into the realization of the first reliable building blocks for quantum computation. The main challenge the field is facing today is unquestionably related to the loss of information due to quantum state decoherence. As indicated by our recent experiments, the perennial problem of decoherence might be solved by fully epitaxial semiconductor-superconductor growth techniques of high quality topological superconducting materials. Moreover, quantum systems based around design principles such as gate-controlled semiconductor-superconductor materials that can hold topologically\u2010motivated symmetry protection, might enable simpler forms of control and less dependence on available control technology.", "To": ["2022-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["716655"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 2 500 000"], "Project_Title": ["Treating mitochondrial disease caused by pathogenic mtDNA mutations"], "Total_Cost": ["EUR 2 500 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["mtDNA-CURE"], "Technology_Description": "This proposal describes a series of powerful experimental strategies to develop a completely novel treatment for mtDNA mutation disease based on identifying unknown mechanisms controlling mtDNA replication. Several hundred different mtDNA mutations affect tRNA genes and impair mitochondrial translation leading to human disease. There is typically heteroplasmy with a mixture of wild-type and mutated mtDNA, and the mutations are acting in a \u201crecessive\u201d (loss of function) way. Very high levels of mutated mtDNA are needed to cause disease in affected patients whereas maternal relatives with high, but sub-threshold levels of mutated mtDNA are completely healthy. The corollary of these observations is that even a small increase of wild-type mtDNA may efficiently counteract disease in affected patients. This hypothesis will be validated by a series of genetic experiments with mice harbouring single pathogenic mtDNA mutations. Furthermore, novel factors controlling mtDNA replication will be identified. In particular, we will elucidate the formation and function of the mammalian displacement (D) loop, which provides a switch between abortive and genome length mtDNA replication. This very fundamental problem in mammalian mitochondrial biology has remained unsolved for decades, but I feel that the innovative experimental strategies I present in this proposal are very powerful and should have a fair chance of being successful. In any circumstance, the project will provide important molecular insights into novel mechanisms relevant for mammalian mtDNA replication. Over the years I have been strongly convinced that congruent results from in vivo and in vitro studies are needed to obtain reliable mechanistic insights and this project is therefore based on the close integration of biochemistry, advanced proteomics and state-of-the-art mouse and fly genetics. Finally, I describe a powerful large-scale screening approach to develop small molecular stimulators of mtDNA replication.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-10-01"], "Project_ID": ["741366"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 2 070 000"], "Project_Title": ["Topological Materials: New Fermions, Realization of Single Crystals and their Physical Properties"], "Total_Cost": ["EUR 2 070 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["TOPMAT"], "Technology_Description": "The topologies of the electronic and magnetic structure in reciprocal and real space underlies much of condensed matter physics. Moreover, the properties of single crystals with particular topological electronic structures can mimic phenomena found in high energy physics and cosmology. New classes of quantum materials are found in insulators and semimetals that exhibit non-trivial topologies: they display a plethora of novel phenomena including: topological surface states; new Fermions such as Weyl, Dirac or Majorana; and non-collinear spin textures such as Skyrmions. A hallmark of many of these new quantum properties that are derived from fundamental symmetries of the bulk, is that they are topologically protected. Just recently a general scheme to identify novel Fermions was proposed that is based on the symmetries and the Wyckhoff positions of relevant space groups. These new types of Fermions are a groundbreaking concept beyond the known Dirac and Weyl and have no high-energy counterparts. The translation of these theoretical concepts into realizable materials is one focus of this proposal. The next step is to apply this approach to magnetic space groups so as to identify new magnetic Fermions. We will engineer these topological materials via synthesising high quality single crystals and by applying for example high magnetic fields and high pressure, to tune topological phase transitions, electrical transport properties and surface states. Particularly high-pressure Hall measurements will be developed. Hall measurements allow the investigation of the fundamental electrical transport properties of topological materials such as their carrier densities, oscillation frequencies, mobilities, and anomalous and topological Hall effects. The PI and her team have already synthesized more than 50 different topological materials as single crystals. To boost topological science in Europe even further a single crystal platform will be established within the proposed project.", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-07-01"], "Project_ID": ["742068"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 2 499 356,27"], "Project_Title": ["Probing chemical dynamics at surfaces with ultrafast atom pulses"], "Total_Cost": ["EUR 2 499 356,27"], "Country": ["Germany", "Germany"], "Project_ACR": ["HBEAM"], "Technology_Description": "Ultra-short light pulses have become invaluable in time-resolved studies in chemistry and physics. But many important processes are initiated by collisions. While lasers have revolutionized experiments using light pulses, experimentally proven concepts for producing ultra-short pulses of neutral matter are still in their infancy. Hence, our ability to control when a collision occurs is still extremely limited. Recently, we have reported bunch-compression photolysis, the first demonstrated method for producing ultra-short pulses of neutral matter. Here, photolysis of jet-cooled hydrogen iodide is carried out with femto-second laser pulses whose frequency bandwidth has been spatially ordered. Thus, fast H-atom photoproducts overtake slow ones, producing an ultra-short pulse.The central objective of this project is to develop bunch-compression photolysis as a tool for ultrafast timing experiments involving collisions of ultrashort pulses of H-atoms at synchronously photo-excited solid surfaces. Bunch-compression photolysis allows collisions at a surface to be synchronized with photoexcitation on the ps time scale, opening up new ways to study the dynamics of collisions at selectively photo-excited surfaces that have not yet relaxed. Studies on collision dynamics involving excitons produced in 2D semiconductors is one exciting direction for this work. Experiments on synchronized H atom collisions with vibrationally excited surfaces prepared by infrared photoexcitation is another - this enables kinetics experiments with surface site-specificity as well as the direct observation of reaction intermediates. The work and ideas presented here show how to overcome the most challenging barrier to a new class of time-resolved dynamics experiments, opening new frontiers in the study of surface chemistry, where we will begin to understand how selected degrees of freedom of the solid influence collision dynamics and reaction rates.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-10-01"], "Project_ID": ["742422"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITAT ZURICH", "UNIVERSITAT ZURICH"], "EU_Contribution": ["EUR 2 383 444"], "Project_Title": ["Noise and robustness in the evolution of novel protein phenotypes"], "Total_Cost": ["EUR 2 383 444"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["NoiseRobustEvo"], "Technology_Description": "Living cells are constantly barraged by perturbations that originate within themselves. Especially abundant \u2013 far more than DNA mutations \u2013 are two kinds of such perturbations. The first is gene expression noise, pervasive stochastic variation of transcript and protein levels. The second is mistranslation noise, the misincorporation of amino acids by ribosomes during protein synthesis. Organisms and protein molecules can evolve robustness \u2013 the persistence of well-adapted phenotypes \u2013 to both kinds of noise. Theory predicts that noise and robustness can affect the adaptive evolution of new proteins, but we do not know whether they help or hinder adaptive evolution. We hypothesize that noise and robustness can accelerate protein evolution both separately and jointly. To validate this hypothesis, we will evolve light-emitting fluorescent proteins towards new color phenotypes via directed laboratory evolution in E.coli. During evolution, we will manipulate expression noise by driving FP expression from noisy or quiet promoters, and we will manipulate mistranslation via host strains with low and high mistranslation rates. We will manipulate protein robustness in three biologically important ways, chaperone overexpression, gene duplication, and stabilizing selection. We will study how fast FPs evolve new colors, and analyze protein evolutionary dynamics through a combination of high-throughput sequencing, engineering of selected adaptive mutations, and data-driven modeling. Our project will show how a ubiquitous but poorly understood source of phenotypic variation affects protein innovation. It will also help engineers discover new protein functions. Moreover, our work will help establish FPs as a major platform to study protein evolutionary dynamics. By revealing noise as a new and crucial factor in protein evolution, our observations have the potential to revolutionize molecular evolution research, much like earlier studies of noise have revolutionized cell biology.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["739874"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 999 292"], "Project_Title": ["Fossil Fingerprinting and Identification of New Denisovan remains from Pleistocene Asia"], "Total_Cost": ["EUR 1 999 292"], "Country": ["Germany", "Germany"], "Project_ACR": ["FINDER"], "Technology_Description": "Scientific analyses of ancient biomolecules (proteins, DNA, hard tissues) have transformed our knowledge of archaic hominins present in Eurasia prior to the expansion of modern humans from Africa. In 2010, a finger bone discovered in Siberia was assigned using DNA to a new, previously unknown human group, the Denisovans. The Denisovans interbred with both Asian Neanderthals and AMH over the past 100,000 years; their geographic distribution is now thought to have stretched from the Siberian steppes to the tropical forests of SE Asia and Oceania.", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-06-01"], "Project_ID": ["715069"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["UNIVERSITAT ZURICH", "UNIVERSITAT ZURICH"], "EU_Contribution": ["EUR 2 103 440"], "Project_Title": ["Drivers of Growth in Bank Lending and Financial Crises"], "Total_Cost": ["EUR 2 103 440"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["lending"], "Technology_Description": "Banking crises are thought to be recurrent phenomena that generally come on the heels of strong credit growth. Their damaging real effects have generated a broad agreement among academics and policymakers that financial regulation needs to tighten and to obtain a macroprudential dimension that aims to lessen the negative externalities from the financial to the macro real sector.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["740272"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 968 125"], "Project_Title": ["High Resolution Extreme Ultraviolet Laser Spectroscopy"], "Total_Cost": ["EUR 1 968 125"], "Country": ["Germany", "Germany"], "Project_ACR": ["XUV-COMB"], "Technology_Description": "Discrepancies between theory and experiments have been fuelling the development of physics from the discrete line spectrum of hydrogen, where classical physics fails, to the Lamb shift, which is unexplained by the Dirac equation. At the precision frontier, comparisons between theory and experiment have been performed almost exclusively with atomic hydrogen. To progress from there, it very good accuracy. The spectroscopic investigation of muonic hydrogen, which was successful recently, was the first step in that direction and has brought up a serious challenge to Quantum Electrodynamics (QED). Even though we could solve this problem in the meantime, there might be others waiting to be discovered when leaving the beaten track of ordinary atomic hydrogen. Besides anti-hydrogen, high resolution laser spectroscopy of singly ionized helium is the next logical item on the list. In addition of representing a hitherto unexplored system, He+ allows for a far better test than atomic hydrogen due to the QED power series expansion of its energy levels in terms of ZWith the nuclear charge Z and the fine structure constant the disputed terms are of the order of (Z)6. Unlike ordinary hydrogen, He+ can be readily stored in an ion trap and sympathetically cooled by co-stored ions with an accessible cooling transition. This approach eliminates essentially all dominating experimental uncertainties that we face with ordinary hydrogen today. The 1S-2S resonance is the sharpest and hence most interesting transition. Its observation requires highly coherent extreme ultraviolet radiation at 60.8 nm which can be generated through high order harmonics from a mode locked laser. The resulting frequency comb is most suitable for a two-photon transition as photons from pairs of modes combine to deliver the excitation energy. Other applications of such new laser source are foreseeable.", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-06-01"], "Project_ID": ["742247"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 2 004 375"], "Project_Title": ["Exosome and ribosome coupling"], "Total_Cost": ["EUR 2 004 375"], "Country": ["Germany", "Germany"], "Project_ACR": ["EXORICO"], "Technology_Description": "To date, mechanistic studies on the macromolecular complexes that synthesize or degrade RNAs or proteins have investigated these machines individually to understand how they execute different steps in the gene expression process. Although the individual complexes catalyze their reactions independently of each other in vitro, increasing evidence suggests that they function in a highly coordinated manner in vivo. The molecular basis for such a coordination remains largely unknown. During the past five years, our group has focused on deciphering the mechanisms of multiprotein complexes that mediate mRNA turnover in S. cerevisiae. Here, I propose to take these analyses to the next level and visualize how a major RNA degradation machine, the exosome, is directly coupled to the protein-synthesis machine, the ribosome. In particular, we want to study two different exosome-ribosome assemblies that underpin opposite outcomes of RNA degradation: a constructive function of the nuclear exosome in the maturation of the large ribosomal subunit and a destructive function of the cytoplasmic exosome in the elimination of ribosome-bound mRNAs. Building on our preliminary data from both the yeast and human systems, we will use a combination of bottom-up biochemical reconstitutions and top-down endogenous purifications to isolate 1) an exosome complex and its nuclear cofactors bound to a pre-60S ribosomal subunit and 2) an exosome complex and its cytoplasmic cofactors bound to a stalled 80S ribosome. We will determine the structures of these ~3 - 4 MDa nuclear and cytoplasmic assemblies using the combined information from cryo-electron microscopy and X-ray crystallography approaches. The structural studies, combined with biochemical and genetic information, will reveal how these machines interact and coordinate RNA metabolism with protein synthesis. Overall, this work will provide important insight into the principles that coordinate different steps of eukaryotic gene expression.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-10-01"], "Project_ID": ["740329"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 872 968,75"], "Project_Title": ["Quantum Emitters in non-conventional baths"], "Total_Cost": ["EUR 1 872 968,75"], "Country": ["Germany", "Germany"], "Project_ACR": ["QUENOCOBA"], "Technology_Description": "The coupling of quantum emitters to a common bath gives rise to intriguing quantum optical phenomena, like super-radiance, non-Markovian dynamics, or dipole-dipole interactions. In recent years, new experimental setups are emerging where non-conventional baths, with tailored dispersion relations, can be produced. In particular, atoms (the emitters) can be kept in the proximity of photonic crystals (the bath), whose properties can be engineered thanks to the spectacular progress experienced in nano-fabrication techniques. Low dimensional mate- rials, dispersion relations with Dirac points, or exotic topological features can be designed in photonic crystals, which will dramatically affect the behavior of the emitters. In this scenario, exotic phenomena, unique possibilities for quantum simulation of both coherent and dissipa- tive dynamics, as well as advanced applications are expected to appear. Presently, a new research area is emerging to investigate the physics of emitters coupled to non- conventional baths.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-09-01"], "Project_ID": ["742102"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 2 048 183"], "Project_Title": ["Big-Data Analytics for the Thermal and Electrical Conductivity of Materials from First Principles"], "Total_Cost": ["EUR 2 048 183"], "Country": ["Germany", "Germany"], "Project_ACR": ["TEC1p"], "Technology_Description": "\"Thermal conductivity (TC) is a key characteristic of many materials, particularly those used in the energy and environment sectors (thermoelectrics, thermal-barrier coatings, catalysis, etc.). However, TC is largely unknown \u2212 of the 225,000 identified inorganic semiconductor and insulator crystals, only 100 have any TC data available.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-10-01"], "Project_ID": ["740233"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITAT ZURICH", "UNIVERSITAT ZURICH"], "EU_Contribution": ["EUR 3 344 108"], "Project_Title": ["Towards a multi-ton xenon observatory for astroparticle physics"], "Total_Cost": ["EUR 3 344 108"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["Xenoscope"], "Technology_Description": "Dark matter is one of the greatest mysteries in the Cosmos, as its intrinsic nature is largely unknown. The identification and characterization of dark matter particles is a major endeavor in physics. XENOSCOPE will be a unique project focussed on essential, cutting-edge research towards a multi-ton dark matter detector using liquid xenon (LXe) as target material. With its low energy threshold, ultra-low backgrounds and excellent energy resolution, a LXe observatory will be highly sensitive to other rare interactions, such as from solar and supernova neutrinos, double beta decays of 136Xe, as well as from axions and axion-like particles. To design and construct a 50 t (40 t in the time projection chamber, TPC) detector, a number of critical technological challenges must first be addressed. Fundamental aspects are related to the design of the TPC, including the identification of new photosensors, the optimization of the light and charge collection (hence the energy threshold and resolution), and the minimization of radioactive backgrounds. XENOSCOPE will address all these aspects through a number of small, medium-size and a full-scale (in the z-coordinate of the TPC) prototypes. The goal is to specify the required input for the technical design of the 50 t detector, to be realized by the DARWIN consortium which the PI leads. Arrays of VUV-sensitive SiPMs will be studied as novel light sensors, and a 4-\u03c0 photosensor coverage TPC will be constructed for the first time. Signal detection will be optimized for both low and high-energy readout, thus drastically increasing the dynamic range of a LXe-TPC. Low-background materials will be identified and characterized not only for the photosensors and their read-out, but for all the components of the detector. Finally, a full scale TPC in the z-dimension, 2.6 m in height, will be designed, built and operated and electron drift and extraction into the vapor phase over such large distances for the first time demonstrated.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["742789"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 918 750"], "Project_Title": ["Exceptional Quantum Gravity"], "Total_Cost": ["EUR 1 918 750"], "Country": ["Germany", "Germany"], "Project_ACR": ["eQG"], "Technology_Description": "Motivated by the overwhelming success of symmetry concepts in formulating basic laws of physics, the present proposal (eQG) seeks to develop a new symmetry based approach to the problem of reconciling Quantum Mechanics and Einstein\u2019s General Relativity into a consistent theory of Quantum Gravity, regarded by many as the greatest challenge of contemporary theoretical physics. The need for such a theory is most pressing for the resolution of black hole singularities and the Big Bang, but it is equally crucial to the search for a consistent UV completion of the Standard Model of Particle Physics and the unification of the fundamental interactions. eQG aims to tackle this problem from a new perspective, bringing together very different strands of development: on the one hand, by paying particular attention to recent advances in our understanding of cosmological singularities and the evidence for novel infinite-dimensional duality symmetries near the singularity that has emerged in supergravity and string theory, and to recent progress in formulating \u2018exceptional geometries\u2019 transcending Riemannian geometry; on the other hand, by exploiting insights from modern canonical quantisation towards a better understanding of the basic degrees of freedom and the dynamics of quantum space-time. The main focus of eQG will be the \u2018maximally extended\u2019 exceptional hyperbolic Kac\u2013Moody symmetry E10, whose uniquely distinguished status makes it a prime candidate symmetry for unifying the known dualities of string and M theory, for a conceptually precise scenario of emergent (quantum) space and time near the singularity, and finally, for replacing supersymmetry as a guiding principle for unification. Consequently, the principal goal of eQG will be to explore how this symmetry can define a theory of quantum gravity, how it acts on its fundamental degrees of freedom, what the special features are of the quantised theory, and what physical predictions can be derived from it.", "To": ["2022-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-12-01"], "Project_ID": ["740209"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 472 000"], "Project_Title": ["A Theory of Reliable Hardware"], "Total_Cost": ["EUR 1 472 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["ToRH"], "Technology_Description": "The complexity of computing hardware keeps increasing at a rapid pace, with no end in sight. With growing number of components and ongoing miniaturization, hardware engineers struggle with an increasing number and variety of faults, yet must guarantee correct operation of the system as a whole. This is hindered by a concurrent increase in design complexity, i.e., the trend of integrating ever more diverse circuits into larger systems, which results in a higher complexity of verifying the correctness of a given design -- especially when providing for the possibility that some components may fail.", "To": ["2022-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-08-01"], "Project_ID": ["716562"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 2 378 958"], "Project_Title": ["Creating an electron-positron plasma in a laboratory magnetosphere"], "Total_Cost": ["EUR 2 378 958"], "Country": ["Germany", "Germany"], "Project_ACR": ["PAIRPLASMA"], "Technology_Description": "The visible Universe is predominantly in the plasma state. On Earth, plasmas are less common, but they find many applications in industry and are also studied with the goal of providing an abundant energy source for mankind through fusion energy. The behaviour of plasmas studied thus far, in particular those that are magnetized, is very complex. The complexity manifests itself first and foremost as a host of different wave types, many of which are generically unstable and evolve into turbulence or violent instabilities. This complexity and the instability of these waves stems to a large degree from effects that can be traced back to the difference in mass between the positive and negative species, the ions and the electrons.", "To": ["2022-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-08-01"], "Project_ID": ["741322"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITAT ZURICH"], "EU_Contribution": ["EUR 187 419,60"], "Project_Title": ["Developing a Financial Econometrics Package for the Julia Programming Language"], "Total_Cost": ["EUR 187 419,60"], "Country": ["Switzerland"], "Project_ACR": ["juliaeconometrics"], "Technology_Description": "Julia is a new programming language started at MIT, with a strong focus on numerical computing. Its key advantage compared to languages like R and Python is that Julia is (just in time) compiled, rather than interpreted. As a consequence, Julia effectively combines the convenience of these high level languages with the speed of compiled low level languages such as C++ or Fortran. Speed of execution is critical in many applications, including but not limited to those involving big data. ", "To": ["2020-01-01, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-02"], "Project_ID": ["750559"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAT ZURICH", "UNIVERSITAT ZURICH"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["REsummation-Improved moNtecarlo eVEnt geNeraTor"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["REINVENT"], "Technology_Description": "With the start of the second run of the Large Hadron Collider and the discovery of a particle compatible with the Standard Model Higgs boson, the high-energy particle physics community faces the task to carry out precise measurements of the properties of this new particle, in order to establish its nature. At the same time, it will be equally important to keep looking for the yet elusive signs of New Physics. Both tasks rely on the ability to accurately predict the expected signals and to disentangle them from the known backgrounds. At hadronic colliders like the LHC, accurate modeling of the strong interactions is crucial to interpret the experimental outcomes.", "To": ["2022-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["714788"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 479 105"], "Project_Title": ["Lifespan Inequalities: Why the age-at-death distribution varies between countries and socioeconomic groups"], "Total_Cost": ["EUR 1 479 105"], "Country": ["Germany", "Germany"], "Project_ACR": ["LIFEINEQ"], "Technology_Description": "Individuals and populations are surviving to ever higher ages. A crucial and timely question for policymakers is whether to direct limited resources toward future life expectancy increases or toward reductions of inequalities in longevity. These inequalities, hereafter referred to as lifespan inequality but also known as age-at-death variation, are large, infrequently summarized, and impose major costs on individuals and society. In order to formulate effective policies to reduce lifespan inequality, we need a deeper understanding of the magnitude and causes of divergent age patterns of mortality decline.", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-07-01"], "Project_ID": ["716323"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["UNIVERSITAT ZURICH", "UNIVERSITAT ZURICH"], "EU_Contribution": ["EUR 2 497 500"], "Project_Title": ["Time in Medieval Japan"], "Total_Cost": ["EUR 2 497 500"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["TIMEJ"], "Technology_Description": "The project explores time in medieval Japan, taking a new approach to historical articulations of the concept of time, based on the theory of symbolic forms. It will examine symbolic representations and social regulations of time in a civilisation that is often juxtaposed to contemporary, globalised modernity. We will investigate into medieval Japan as a dynamic and internally differentiated society, and not as a unified \u201ctraditional\u201d culture dominated by a qualitative concept of time. We will focus on its plural ways of registering, measuring, articulating, and regulating time. The aim is to disclose the specific cultural practices operative in the respective ways of negotiating time, and to achieve a more comprehensive and detailed account of human strategies in dealing with this fundamental restriction of our existence. In a closely coordinated set of case studies, we examine representative spheres connected to various symbolic forms and socio-cultural agendas: the Zen monastery, the female court, and the market. An intersectional case study explores the symbolic mediations of the menstrual cycle, connecting these spheres and uniting aspects of the physical, ritual and symbolic regulation of human body time. Each case study explores the symbolic forms prevalent in the respective settings, and the aspects of time that are deemed relevant and selected for symbolic articulation. We will analyse temporal encoding, structure and application in the regulation of affairs, the competence to account and regulate these processes, and the influence on feelings of dismay in the face of the socio-cultural realities of time. Special attention is paid to the conflicts that arise when established regimes of temporal regulation and expression clash with each other and with individual experience. The results will be compared to the history of time in the Western world, and integrated into a theory of the symbolic forms of time.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["741166"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 2 457 500"], "Project_Title": ["Mapping the Cosmic Gas Supply with ALMA"], "Total_Cost": ["EUR 2 457 500"], "Country": ["Germany", "Germany"], "Project_ACR": ["Cosmic_Gas"], "Technology_Description": "The molecular gas phase is the material in galaxies out of which stars form. As such, it is the quantity that controls the star formation rate of a galaxy, thereby the overall stellar mass build-up, and ultimately galaxy evolution through cosmic times. In contrast to studies of the stellar mass and star formation, characterizing this fuel supply in galaxies as a function of cosmic epoch is still in its infancy. The ALMA facility now redefines our ability to map out the cosmic cold gas supply, essentially unknown at present. This ERC proposal is based on extensive approved observational ALMA programs, led by the PI: ASPECS is the first-ever approved ALMA large (150h) program, aimed at providing a comprehensive view of the baryon cycle from gas to stars over cosmic time. ASPECS will provide 3D molecular scans in two ALMA bands of the Hubble Ultra Deep Field -- the iconic cosmological deep field. A second focus is the detailed characterization of the molecular gas content at z>6 in host galaxies of the most distant quasars via ALMA. This will assess the role of cold gas in the build-up of the first (t_Universe < 1 Gyr) massive cosmic structures in the Universe, again through significant approved ALMA programs led by the PI\u2019s group. The studies outlined here will fully capitalize on the unparalleled capabilities of ALMA to map out the cosmic gas supply through cosmic history, and will provide crucial insights to define observational strategies for JWST (the PI is member of the European JWST/MIRI science team). Through his track record, past achievements in the field of galaxy evolution studies, and through the available proprietary data, the PI is uniquely positioned to lead this ambitious program, which will define the global state-of-the-art in cosmological galaxy evolution through high-redshift ISM studies.", "To": ["2022-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-11-01"], "Project_ID": ["740246"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 483 750"], "Project_Title": ["Neural circuits for route planning in goal-directed spatial navigation"], "Total_Cost": ["EUR 1 483 750"], "Country": ["Germany", "Germany"], "Project_ACR": ["NavigationCircuits"], "Technology_Description": "Spatial navigation is a fundamental ability for animals to survive in a geometric space. A prominent feature of rats is their ability to create an internal metric space, or a map, in their brain. While place cells in the hippocampus are considered key elements of the spatial representation system, the activity of these cells primarily depends on the animal\u2019s instantaneous position; thus it is not clear how the brain computes an estimate of future positions, necessary for route planning. Although several ideas have been proposed to extract future representations from place cells, how such information is used in downstream brain structures is still largely unknown. I thus propose to clarify the roles of the hippocampus in the larger context of brain circuits for route planning. A growing body of evidence indicates key roles for the medial prefrontal cortex (mPFC) and the retrosplenial cortex (RSC) in navigation. I hypothesize that RSC, downstream of hippocampal area CA1, may represent the animal\u2019s future position by making use of information from place cells about positions and movements. The future positions may then be evaluated in mPFC, a downstream target of RSC and CA1, which potentially represents the spatial proximity to the goal. I will clarify the key circuit dynamics during route decisions among these structures together with the hippocampus. As route planning requires information about positional relationships in the environment, I will also investigate a role for brief trajectory sequences generated by place cells, or replay, for transferring such information from the hippocampus to RSC. Simultaneous high-density recordings from multiple regions as well as optogenetic silencing of specific projections are all available in freely behaving rats, and extensive use of computational methods will help decipher the codes in navigation circuits. The studies will provide key insights into how internal models in the brain influence cognition and behaviour.", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-05-01"], "Project_ID": ["714642"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Functional Analysis of Host Genetic Variants: Biomarker Selection Towards Improving Female Subfertility Diagnosis and Treatment"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["HOST-SELECT"], "Technology_Description": "Roughly 15% of couples trying to conceive suffer from subfertility. One of its leading causes is developed pathology in woman\u2019s fallopian tubes (tubal pathology or TP). Persistent infection with Chlamydia trachomatis (CT) is the single most common cause of TP. Women with a certain genetic makeup are more likely to develop TP after CT infection. I have so far identified 8 host genes and 13 genetic variants associated with CT infection and TP. Their exact function is, however, not yet elucidated. In this project, I will research the effect of found host genetic factors on CT infection and TP, by analysing their function in a human fallopian tube organoid model. This model optimally simulates in vivo conditions in the tubes. The host institution offers the technology and expertise for conducting such research.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-07-01"], "Project_ID": ["752999"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Quantum Dynamics Beyond the Born-Oppenheimer Picture: Making the most of wave function and trajectory-based approaches"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["BeBOP"], "Technology_Description": "The experienced researcher, Dr. Guillermo Albareda, and the host supervisor, Prof. Angel Rubio, aim at developing a new predictive and practical approach that overcomes the difficulties that current methods have to treat the correlated electron-nuclear dynamics in complex systems. ", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-10-01"], "Project_ID": ["752822"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAT ZURICH", "UNIVERSITAT ZURICH"], "EU_Contribution": ["EUR 1 999 991"], "Project_Title": ["Brain networks controlling social decisions"], "Total_Cost": ["EUR 1 999 991"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["BRAINCODES"], "Technology_Description": "Successful social interactions require social decision making, the ability to guide our actions in line with the goals and expectations of the people around us. Disordered social decision making \u2013 e.g., associated with criminal activity or psychiatric illnesses \u2013 poses significant financial and personal challenges to society. However, the brain mechanisms that enable us to control our social behavior are far from being understood. Here I will take decisive steps towards a causal understanding of these mechanisms by elucidating the role of functional interactions in the brain networks responsible for steering strategic, prosocial, and norm-compliant behavior. I will employ a unique multi-method approach that integrates computational modeling of social decisions with new combinations of multimodal neuroimaging and brain stimulation methods. Using EEG-fMRI, I will first identify spatio-temporal patterns of functional interactions between brain areas that correlate with social decision processes as identified by computational modeling of behavior in different economic games. In combined brain stimulation-fMRI studies, I will then attempt to affect \u2013 and in fact enhance \u2013 these social decision-making processes by modulating the identified brain network patterns with novel, targeted brain stimulation protocols and measuring the resulting effects on behavior and brain activity. Finally, I will examine whether the identified brain network mechanisms are indeed related to disturbed social decisions in two psychiatric illnesses characterized by maladaptive social behavior (post-traumatic stress disorder and autism spectrum disorder). My proposed work plan will generate a causal understanding of the brain network mechanisms that allow humans to control their social decisions, thereby elucidating a biological basis for individual differences in social behavior and paving the way for new perspectives on how disordered social behavior may be identified and hopefully remedied.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["725355"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Mechanisms of collective predator detection and information transfer in African ungulates"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["UNGULATE"], "Technology_Description": "One benefit of sociality in animals is collective predator detection, which provides early warning of threats and enables more effective escape responses. For collective detection to occur, information regarding the presence of predators must be transferred from knowledgeable to na\u00efve individuals. The mechanisms of information sharing have rarely been studied outside of laboratory settings, and for most species it is unclear how information transfer is achieved and how the reliability of transfer is affected by social, ecological, and behavioral factors. Using UAV-based aerial video technology and novel computer vision techniques, The Experience Research (ER) will study the mechanisms of information transfer in groups of African ungulates in their natural savannah habitats. The ER will observe unperturbed herds, and conduct field experiments in which she present threatening stimuli to groups and observe how awareness of the stimuli spreads through the group. Using custom-built automated tracking software, the ER will quantify the behavior of every individual within each group and combine this data with computationally reconstructed visual fields and 3D habitat models. This dataset will enable her to precisely identify the visual information available to each individual continuously throughout each trial and explicitly consider the role of this information in driving individual vigilance strategies in the absence of immediate threats. In undertaking this project, the ER will adapt quantitative methods developed for laboratory settings for use in stochastic, large-scale field studies. This research programme will shed new light on the benefits of sociality, a classic topic in animal behavior, and promote the use of novel quantitative approaches in field studies that will advance the field of behavioural ecology.", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-08-01"], "Project_ID": ["749499"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Role of Listerin ubiquitin ligase in MHC-I antigen presentation"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["IMMUNO-RQC"], "Technology_Description": "Mammalian cells present a fingerprint of their proteome through the display of endogenous peptides on MHC-I complexes. This allows for CD8+ T cells to recognize and kill cells infected with viruses or other intracellular parasites, or cells accumulating aberrant proteins resulting from malignant transformation. The MHC-I peptides originate from protein degradation by the ubiquitin proteasome system, which is responsible for controlled protein turnover. This would mean that viral proteins, which are typically very stable, would escape monitoring. Nevertheless, cells are able to mount an MHC-I immune response minutes after viral infection. Most MHC-I presented peptides are therefore thought to originate from newly synthesized, defective ribosomal products (DRiPs), rather than proteins at the end of their lifespan. Although there is a growing body of evidence showing that antigen presentation is better correlated with protein synthesis rather than protein stability, characterization of the underlying cellular pathway is lacking. Recently, the E3 ubiquitin ligase Listerin has been shown to mark nascent polypeptides resulting from defective mRNAs for degradation. Here we test the hypothesis that this pathway contributes to the production of peptides for MHC-I loading. Our major aim is therefore to investigate the involvement of Listerin in antigen presentation, using 3 different approaches: I) proof-of-principle experiments analyzing the rate of MHC-I presentation of a model protein, comparing the efficiency of its presentation when expressed from an intact or defective mRNA, and when expressed in WT or Listerin knock-out cells; II) global characterization of the MHC-I peptidome of WT and Listerin knock-out cells using mass spectrometry; III) quantitative analysis of the fraction of newly-synthesized proteins undergoing the RQC pathway, and of its possible correlation with the MHC-I peptidome.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-05-01"], "Project_ID": ["749932"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAT ZURICH"], "EU_Contribution": ["EUR 175 419,60"], "Project_Title": ["The evolvability of bacterial multicellularity"], "Total_Cost": ["EUR 175 419,60"], "Country": ["Switzerland"], "Project_ACR": ["EBM"], "Technology_Description": "There are numerous evolutionary origins of multicellularity. Yet, only in a few cases was the origin of multicellularity also followed by an enormous diversification of multicellular forms and functions. This raises the question what determines the evolvability of multicellular phenotypes, i.e. their capacity to undergo evolutionary change? I will study the evolvability of one of the simplest forms of bacterial multicellularity: colony formation in the Bacilli. Despite their simplicity, Bacilli can express a wide range of colony morphologies. The physical forces that shape these morphologies are well understood. In addition, there is a detailed understanding of the gene regulatory network (GRN) underlying colony formation and ample of genomic data. I will study how the GRN underlying multicellularity affects its evolvability. First, I will determine which evolutionary changes in the GRN are associated with the diversification of colony morphologies. To this end, I will construct a phylogenetic tree of the Bacillales, compare all genomes and identify the genetic changes that correlate with changes in colony morphology. Second, I will determine if and how these genetic changes give rise to changes in colony morphology. I will construct Bacillus subtilis mutants, which harbor the identified genetic changes, and examine how their colonies develop. Since colonies come about through the feedback between cells and their environment, I will use a unique combination of state-of-the-art biotechnologies to trace the transcriptomic and environmental changes in the colony over time. This will give an extraordinary detailed account of colony development in the Bacilli. Finally, I will examine why the morphological diversification of colonies was favored by selection, by studying the functional properties of colonies. Altogether, this will be the first comprehensive analysis on the evolvability of multicellularity, thereby giving a unique glimpse on how evolution innovates.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["742235"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Global Climate change impact on phenOtype and ePigenomE stability: Accessing plant adaptability through a 2050 simulation model"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["COPE-50"], "Technology_Description": "One of the key challenges in the 21st century will be food security. Computer modelling using historical data predicts a climate shift towards combination of increasing temperature, rising carbon dioxide (CO2) levels and high Ultraviolet (UV) radiation. Such climatic change could negatively affect productivity of the agricultural systems and thus availability of food for the growing world\u2019s population, which is a very serious concern. However, most of the current debate is based on little experimental evidence. Therefore, we aim to address this question by establishing a strong backbone of phenotypic and molecular data in the frame of the proposed project. Our first objective will be to examine the impact of the predicted 2050 climate on the morphological and physiological performance of the model and the crop plants. Adaptation of plants to environmental cues occurs also at the gene transcriptional level and is widely controlled by epigenetic means. Therefore, in the second objective we will study plant chromatin changes in response to predicted climatic change and their effects on plant phenotypes. Our study will act as a resource to framework the phenotypic and molecular mechanism by which these environmental variations affect crop yields and current estimates of future impacts of climate. Hence, the longer term goal of the project is to contribute towards solving the current food security issues by providing valuable resource of data for scientists along with the strategy makers.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-06-01"], "Project_ID": ["747718"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAT ZURICH"], "EU_Contribution": ["EUR 175 419,60"], "Project_Title": ["Probabilistic neuromorphic architecture for real-time Sensor fusion applied to Smart, water quality monitoring systems"], "Total_Cost": ["EUR 175 419,60"], "Country": ["Switzerland"], "Project_ACR": ["ProbSenS"], "Technology_Description": "\u201cProbSenS\u201d will develop a novel low-power event-driven probabilistic Very Large-Scale Integration (VLSI) architecture for real-time, adaptive and robust multisensor integration. Multisensor integration exploits the extended coverage of multiple detectors to increase perceptual confidence in Smart Systems, but embedded implementations are yet in their infancy due to the lack of hardware able to infer from the multivariate, nonlinear, time-dependent and noisy signals supplied by modern sensors. By using principles of how biological systems promptly combine multisensory information and generate meaningful features in dynamic and uncontrolled real-world conditions, bioinspired Generative Deep Neural Network (GDNN) models are emerging as a powerful, CMOS-amenable computing paradigm to accelerate sensor fusion and enable quick, reliable self-learning and context-awareness under these constraints.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["747848"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAT ZURICH"], "EU_Contribution": ["EUR 175 419,60"], "Project_Title": ["Neuromorphic EMG Processing with Spiking Neural Networks"], "Total_Cost": ["EUR 175 419,60"], "Country": ["Switzerland"], "Project_ACR": ["NEPSpiNN"], "Technology_Description": "The aim of the NEPSpiNN project is to realize a neuromorphic event-based neural processing system that can directly interface with a commercial surface electromyography (sEMG) for the extraction of signal features and classification of the motor neurons output activities. ", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["753470"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["The role of tRNA processing and modifications in protein quality control."], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["MOD-PROT"], "Technology_Description": "Translation of the genetic code into functional proteins is a fundamental biological process essential for cell survival and function. tRNAs are critical in this process because they recognize the codons on the messenger RNA and bring the cognate amino acid to the nascent peptide. To become functional, tRNAs undergo a series of processing steps and chemical modifications. Recently, my host group discovered that cells lacking wobble uridine modifications in the tRNA anticodon display translational slow down, a defect that triggers widespread protein aggregation in yeast and nematodes. These findings were the first to link tRNA metabolism to protein quality control and established tRNA metabolism as a novel layer in the regulation of protein homeostasis. However, the mechanisms underlying this phenomenon remain unknown.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2018-09-01"], "Project_ID": ["746340"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["A microfluidic cryofixation method for time-resolved correlative microscopy"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["umCryofix"], "Technology_Description": "Correlative microscopy, connecting live-cell fluorescence microscopy with electron microscopy (EM), is a powerful tool to relate a dynamic cellular process to the relevant cellular ultrastructure leading to better understanding of fundamental mechanisms, and further, the underlying cause of disease. This is not only important for fundamental science but can guide diagnostic and treatment efforts for virtually any affliction, ranging from Alzheimer\u2019s disease, to HIV, to cancer. In this work, I propose a novel microfluidic cryofixation method that enables time-resolved correlative microscopy. The new method dramatically improves the time resolution with which live images can be correlated to EM images by eliminating the need to transfer the sample from the light microscope to a dedicated cryofixation machine. Current state-of-the-art systems require at least one second while preparation times up to a few minutes are common. Here I propose a new microfluidics-based paradigm that will overcome this barrier by carrying out cryofixation directly within the field of view of a light microscope. This method allows a dynamic process to be arrested at a known time, so that it can be correlated to cellular ultrastructure in EM images. This new method is a critical advance for studying dynamic processes such as membrane trafficking, cell division, and synaptic transmission.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-06-01"], "Project_ID": ["749830"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Active Resonator Development for nano-EPR of single crystal proteins"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["Act-EPR"], "Technology_Description": "In order to keep up with societal challenges of the 21st century, we must devise sustainable ways to efficiently store and retrieve energy from hydrogen. This \u201chydrogen economy\u201d is one path for the future of clean energy. Nature\u2019s solution to this challenge is a branch of enzymes called hydrogenases which typically use an organometallic active-site to reversibly split molecular hydrogen to hydrogen-ions and energy, in the form of electrons. Here, we choose to focus on [FeFe]-hydrogenase due to its high catalytic behavior. To understand these metallo-enzymes we must be able to study the enzymes grown as a single crystal. Single crystal protein Electron Paramagnetic Resonance (EPR) experiments are the ultimate method to study the paramagnetic states of hydrogenases and obtain the full magnetic interactions reflecting the electronic structure of the active site. Ultimately the catalytic activity of the hydrogenase can be understood by relating the information of the magnetic principal axes to the known protein structure of the enzyme. However, the application of single-crystal EPR is severely limited by the small crystals sizes that are usually available (sub-nanoliter to nanoliter volumes). The Key Enabling Technologies outlined in this fellowship have the potential to increase the sensitivity of EPR by a factor of 30 through the application of highly innovative concepts based on planar micro-resonators (PMR). This technology provides the sensitivity needed for the applicant to be the first to study single crystals of the [FeFe]-hydrogenase enzyme with EPR and advance the \u201chydrogen economy\u201d.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-05-01"], "Project_ID": ["745702"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 999 998"], "Project_Title": ["Structural Studies on Focal Adhesions"], "Total_Cost": ["EUR 1 999 998"], "Country": ["Germany", "Germany"], "Project_ACR": ["FocAd"], "Technology_Description": "Focal adhesions (FA) are gigantic protein complexes whose formation is triggered by integrin ligand activation. FAs represent (1) a sensing platform and anchoring points to the outside environment and, (2) a machinery to transduce this information by initiating signaling pathways for cell growth, survival, migration and polarization. Failure in the regulation of FA leads to developmental defects and contributes to the formation of aggressive cancers. Hence, understanding FA formation is the basis for counteracting these detrimental effects. Recently, mass spectrometry and advanced light microscopy clarified players involved in the FA assembly and implicated sophisticated regulation networks of membranes and actin cytoskeletons in the growth of FAs. However, the molecular mechanisms of FA formation and signaling still remain unclear.", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-07-01"], "Project_ID": ["724209"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 931 303"], "Project_Title": ["The chemistry and physics of RNP granules: how they form, age and cause disease"], "Total_Cost": ["EUR 1 931 303"], "Country": ["Germany", "Germany"], "Project_ACR": ["PhaseAge"], "Technology_Description": "Recent studies suggest that defective ribonucleoprotein (RNP) granules and altered RNA processing cause neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). However, defective RNP granules only develop late in life, suggesting that young cells have mechanisms in place to prevent their formation. We recently demonstrated that physiological RNP granules form through phase separation in the cytoplasm and adopt a liquid-like state, but with time transition into an aberrant disease-associated state with solid material properties. Focussing on this conceptual advance, we will", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-04-01"], "Project_ID": ["725836"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Middle Palaeolithic projectile weapon TIPs: a regional and assemblage scale perspective on Neanderthal POINT technologies across Europe"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["TIP-N-POINT"], "Technology_Description": "Stone-tipped hunting weapons are an important marker of the technical and cognitive capacities of Palaeolithic hominins and represent a crucial tipping point in human behavioural evolution. Neanderthals were skilled hunters, as indicated by zooarchaeological and isotope analyses, but preserved remains of organic spears are sparse and potential lithic weapon tips are not ubiquitously present during the Middle Palaeolithic (MP, ca.300,000-40,000BP). Unravelling this enigma and reconstructing the technology underlying MP hunting events is one of the key challenges in studies of Neanderthal behaviour.", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-11-01"], "Project_ID": ["745662"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Quantum Artificial Neural Networks with Tensor Network Algorithmus"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["Q-ANNTENNA"], "Technology_Description": "During the recent years, modern machine learning (ML) has sparked a revolution in areas so diverse as computer vision, voice recognition, medical diagnosis and finance. On its own, quantum information processing (QIP) has also gained tremendous momentum and a novel field, quantum machine learning (QML), has emerged from the intersection of the two disciplines. Interestingly, much of the understanding underlying the last revolution of ML is strongly connected to insights gained from condensed matter and statistical physics. It is then natural to use well-understood techniques to describe quantum many-body systems, namely, tensor networks (TN) in the context of ML.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-04-01"], "Project_ID": ["748549"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAT ZURICH"], "EU_Contribution": ["EUR 175 419,60"], "Project_Title": ["Multi-particle scattering amplitudes for precision collider physics"], "Total_Cost": ["EUR 175 419,60"], "Country": ["Switzerland"], "Project_ACR": ["MPAmplitudes"], "Technology_Description": "Scattering amplitudes determine the probability of interactions between fundamental particles. They are essential ingredients for phenomenological predictions in high-energy physics. Experiments at modern colliders, such as the Large Hadron Collider (LHC) at CERN, are probing fundamental interactions at previously unexplored scales of energy. The high energy involved in these interactions is responsible for the production of many particles in the final state, which needs to be theoretically understood with high accuracy in order to make the most out of experimental data. The goal of this research project is the analytic calculation of multi-particle scattering amplitudes at higher orders in perturbation theory, and in particular the two-loop five-point amplitudes in quantum chromodynamics, needed for theoretical predictions at next-to-next-to-leading order in perturbation theory. These are of great relevance for LHC phenomenology, since our success in finding new physics can depend on our capability of distinguishing its effects from the large QCD background of multi-particle processes, which needs to be known with high precision. The method used for the calculation builds upon state-of-the-art techniques, such as multi-loop integrand reduction and generalized unitarity. These techniques exploit the knowledge of the universal analytic and algebraic structure of amplitudes, and are suited for handling the complexity of multi-particle calculations. The technologies and tools which will be developed for this project are very general and will thus provide a framework useful for future precision calculations, opening up a new frontier for high-precision multi-particle theoretical predictions for collider experiments.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["746223"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 251 611,20"], "Project_Title": ["Temporal predictions in the auditory cortex: neural mechanisms and their specificity across species and stimulus domains"], "Total_Cost": ["EUR 251 611,20"], "Country": ["Germany"], "Project_ACR": ["BrainPredictDynamics"], "Technology_Description": "Following a recent paradigm shift in neuroscience, the brain is often thought to generate active predictions of its environment. Neural predictions of temporal information, in particular, are a current research frontier. A key challenge is to provide a unifying mechanistic explanation of neural expectations ranging from microscopic electrophysiology, via models of interacting populations of neurons, to macroscopic signals observed non-invasively. Auditory and speech perception are the optimal testing ground for studying temporal dynamics of predictive processing in the brain, as most auditory signals only gain meaning as temporal sequences. ", "To": ["2021-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2018-09-01"], "Project_ID": ["750459"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Mapping the Intraflagellar Transport - A High-resolution Study of Intraflagellar Transport Trains in Chlamydomonas Cells"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["TRAIN SPOTTING"], "Technology_Description": "Cilia are highly conserved eukaryotic organelles that, with the exception of fungi and higher plants are present in nearly all types of organisms from protists to mammals. Through their motility, sensory, and signaling functions cilia play crucial roles in human physiology and development. Defects in cilia have profound impact on human health. Cilia assembly requires a dedicated protein shuttle, intraflagellar transport (IFT), a bidirectional motility of multi-megadalton protein arrays along ciliary microtubules. Although the overall mechanism of transport is generally described, complete high resolution structural description is necessary for the detailed understanding of this complex system.", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-08-01"], "Project_ID": ["753954"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Population genomics and experimental evolution of ribosomal RNA gene variants in Arabidopsis thaliana"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["rDNAevol"], "Technology_Description": "The central importance of ribosomal RNA genes (rDNA) for our understanding of biology cannot be overstated: they are evolutionarily the oldest genes, they are the most highly expressed genes in any organism, and their expression is central to cellular growth. Because of the requirement for large quantities of rRNA, eukaryotic genomes contain clusters with hundreds to thousands of rDNA copies arranged in tandem. Despite their high copy number, there is little sequence variation across all rDNA genes within an individual and across individuals in a given species, due to the still mysterious process of concerted evolution. Since not all rDNA copies are expressed, we can already suspect that selection cannot act directly on all rDNA copies. Although our understanding of concerted evolution, and the molecular mechanism how it is achieved (homogenization), has improved over the last decades, no attempt to study it in the context of silent or active rDNA clusters has been made. In the described research programme I will take full advantage of the model plant Arabidopsis thaliana to attack this important connection. The diversity of genetic resources available such as experimental populations to effectively unlinked its two rDNA clusters, the large catalog of over 1,001 publicly available re-sequenced genomes combined with corresponding expression data, as well as its accessibility for genetic manipulation make it an ideal system to pursue the following specific aims: (1) Perform a population genomic analysis of the sequence variability within silent and active rDNA clusters, (2) Generate targeted induced mutations in rDNAs by genome editing to (3) describe the fate and fitness of both natural rDNA variants and newly induced mutations.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-04-01"], "Project_ID": ["752846"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Identifying and deciphering the mechanism of the cellular machinery responsible for disaggregation of intracellular prion-like Tau aggregates"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["REVERSING TAUOPATHY"], "Technology_Description": "Tauopathies are a group of neurodegenerative diseases, the most common of them being Alzheimer\u2019s disease, which are associated with the aggregation of protein Tau in the brain. Despite major research efforts world-wide, the mechanism of Tau aggregation and its pathogenesis giving rise to such neurodegenerative diseases is not yet understood. Therapeutics to cure these tauopathies, including Alzheimer\u2019s disease, are urgently needed. We aim to identify the conditions, the cellular machinery responsible and the mechanism of disaggregation of intracellular prion-like Tau aggregates in HEK293 cell lines, with one condition already been identified (starvation). For identifying the conditions of disaggregation, high resolution confocal microscopy will be used for visualizing intracellular Tau aggregates tagged with yellow fluorescence protein (YFP). For deciphering the cellular components responsible for disaggregation, the proteins associated with the aggregates will be identified using quantitative mass spectrometry from SILAC (stable isotope labeling with amino acids in cell culture) labeled cells. Moreover, candidate factors will be downregulated by siRNA to establish their involvement in aggregate disassembly. Such components individually and in combination will then be analyzed for their disaggregation activity in vitro using filter trap assay for the quantification of disaggregation. Cryo-electron tomography of Tau aggregates under various conditions (e.g. during disaggregation) will be carried out in collaboration with Prof. Wolfgang Baumeister (MPIB). Besides contributing to the benefit of humankind, the proposed research work on neurodegenerative diseases will allow me to grow as a researcher and will help me in realizing my true potential as a scientist. The MPIB and the Hartl lab in particular will play an important role in this regard due the availability of state-of-the-art research facilities and an intellectually stimulating environment.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-06-01"], "Project_ID": ["749370"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 753 125"], "Project_Title": ["Solving The Pathway of LADDERane biosynthesis"], "Total_Cost": ["EUR 1 753 125"], "Country": ["Germany", "Germany"], "Project_ACR": ["STePLADDER"], "Technology_Description": "Ladderanes are highly unusual hydrocarbon moieties with linearly concatenated cyclobutane rings. They are found in the membranes of bacteria performing anaerobic ammonium oxidation (\u201canammox\u201d). How these complicated molecules are produced is expected to involve both novel enzymes and specially evolved versions of known proteins, but the details remain enigmatic. How do these enzymes assemble such intricate carbon skeletons? How do they control the complex stereochemistry involved? How do they deal with the typical nonreactivity of hydrocarbons? And how do they overcome the ring strain inherent in these molecules? Answering these and other questions about the molecular mechanism of ladderane biosynthesis will open up new frontiers in enzymology. ", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-06-01"], "Project_ID": ["724362"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Modelling superconductivity and spin-related effects in hybrid molecular/two-dimensional materials"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["SuperSpinHyMol"], "Technology_Description": "At the intersection of materials science, solid-state physics and quantum chemistry, the design of novel materials in which two or more physical properties are combined into the same solid is currently attracting important attention. In this project, we propose the development of a new generation of hybrid molecular/two-dimensional materials formed by a coordination complex processed into a two-dimensional superconducting substrate (e.g. CuPc@NbSe2 or [V(C3S5)3]@TaS2). The selected molecules to form such architectures are nanomagnets that can be used as molecular spin qubits, the irreducible components of any quantum technology. By using state-of-the-art first-principles methods combined with recent theoretical developments in the host group we intend to establish a full theoretical and computational framework for the rational design of these new hybrid nanomaterials, which can potentially enable the coherent coupling between distant molecular spin qubits through new superconducting phases. With this aim in mind, we will simulate their electronic properties in the normal and superconducting phase, as well as the spin-related effects that will take place due to the interplay between molecular magnetism and superconductivity at the nanometre scale. SuperSpinHyMol will be hosted by a leading expert in the field, Prof. \u00c1ngel Rubio, director of the MPSD (Germany) and will also involve collaboration with top international experimental groups, which will fabricate and characterise the proposed materials. Thus, the theoretical results of this project will be benchmarked against high-resolution experiments and refined when necessary. In the long-term, the progress of this project is expected to have profound impacts on materials science, condensed matter physics, as well as molecular magnetism, providing the foundations to guide the design of new nanodevices using chemical engineering for future advances in quantum computing and molecular spintronics.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-10-01"], "Project_ID": ["751047"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Targeting of host proteins by unrelated pathogen effectors and their surveillance by allelic immune receptors"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["TOPPER"], "Technology_Description": "Pathogens secrete effectors into host cells to promote virulence and often establish disease by interception of basal defence components. One widespread mechanism of disease resistance in plants requires nucleotide-binding oligomerization (NOD)-like receptor (NLR) genes. Recognition of an effector by a cognate NLR prevents pathogen proliferation. A co-evolutionary arms race between the host barley and the pathogenic powdery mildew fungus Blumeria graminis forma specialis hordei (Bgh) has driven the functional diversification of allelic NLR variants encoded at the MLA disease resistance locus (for Mildew locus A). Recent work revealed that Bgh effectors detected by allelic MLA receptor variants are unexpectedly sequence-unrelated and evolved independently from different ancestors. Additionally, the MLA orthologs in wheat and rye, Sr33 and Sr50, confer isolate-specific resistance to the stem rust pathogen Puccinia graminis forma specialis tritici (Pgt). This is remarkable because rust and mildew fungi belong to different phyla and cannot encode sequence-related effectors. MLA variants can therefore not have diversified to directly bind sequence-related effectors and thus monitor effector-mediated modifications of host targets conserved between different cereals. ", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2018-09-01"], "Project_ID": ["742263"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Minirhizotron: Phenology And Root TraitS"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["Mr.PARTS"], "Technology_Description": "Mr.PARTS investigates plant belowground carbon investment and the timing of root development. Root turnover is an important part of global carbon (C) cycles and plants may alter investment into root systems due to nutrient imbalances or droughts as well as under anthropogenic global change. However, soils are difficult to study and root biomass is highly spatially and temporally variable, especially as seasonal timing (phenology) of aboveground plant events may affect resource investment and growth periods belowground. I focus on advancing specially designed camera systems for belowground observatories (minirhizotrons; MR) for non-destructive root/soil system observation and repeatable quantification of root biomass, life/death status and traits, using frequent automated data collection and automatic data processing. I will develop new MR instruments and deploy them first in a greenhouse-based mesocosm at the host institution in a controlled and well monitored setting, then a transfer to the field in a thoroughly instrumented (e.g. multiple height eddy covariance CO2, above-ground phenology cameras, soil lysimeters) study site as part of an ecosystem-scale experiment manipulating nutrient stoichiometry in a seasonally dry savanna in Spain. Data streams from the MR instruments will be processed by machine learning techniques and compared and calibrated against manual measurements of root biomass and root traits made via conventional destructive soil coring as well as whole system above-ground phenology, water and carbon budgets, to identify links between above- and belowground phenology as well as root control over ecosystem C fluxes. In addition, a paired 13C isotope labelling experiment will investigate C partitioning to non- root biomass building pools (e.g. root exudates, mycorrhizal fungi, maintenance respiration) to produce an integrated budget of plant belowground C investment and the controls on root production.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-06-01"], "Project_ID": ["748893"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Molecular mechanisms of the mechanical interaction between the cell nucleus and the actin cytoskeleton"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["MiMEtiC"], "Technology_Description": "The cytoskeleton plays a pivotal role in growth, development, and disease by sensing mechanical stress and mediating structural remodeling and cell functional responses. The cytoskeleton, which is linked directly to the nuclear lamina and thereby to chromatin, has recently been proposed to impact on chromatin remodeling and transcriptional activity. However, the mechanisms and biological consequences of force-dependent chromatin remodeling have remained elusive. Within this context main goals for my project are 1) to characterize nuclear rheology and stress transmission over the nuclear-cytoskeletal linkage, 2) to identify molecular mechanisms of force transmission into the nucleus and 3) to develop a numerical model of cell contractility and remodeling to systematically and quantitatively investigate the stress transmission to the nucleus to test my hypothesis that global force application to the nucleus can control nuclear mechanics, chromatin structure and transcriptional activity in a predictable, biologically meaningful way.", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-03-01"], "Project_ID": ["748004"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Active Organ Phantoms for Medical Robotics"], "Total_Cost": ["EUR 150 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["ACTIVEPHANTOM"], "Technology_Description": "Robot-assisted and minimally invasive medical procedures are impacting medical care by increasing accuracy, reducing cost, and minimizing patient discomfort and recovery times after interventions. Developers of commercial robotic surgical systems and medical device manufacturers look for realistic phantoms that can be used in place of animal experiments or cadavers to test procedures and to train medical personnel. Existing phantoms are either made from hard materials, or they lack anatomical detail, and they are mainly passive and thus unrealistic. ", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-03-01"], "Project_ID": ["737530"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Multidimensional Analysis of Axis Patterning in Plant Embryo"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["MAAP"], "Technology_Description": "Plant cells are immobile, therefore positional signaling is essential for body patterning. While many genes involved in positional signaling in plants are known, we currently lack a mechanistic understanding of their functions. Embryonic axis pattering is the earliest and simplest instances of positional signaling. In Arabidopsis thaliana, embryo is initially radial symmetry. Soon after, the embryo switches to bilateral symmetry and development continues along the newly-established axis. How these patterns emerge from a small group of homogeneous cells remains a fundamental unanswered question in developmental biology. Answering this question requires an in-depth analysis of the spatio-temporal relationship between gene expression and cellular patterns. Today, advanced microscopy and latest image analysis allow us to quantify division, growth and gene expression in individual cells throughout embryogenesis. The host group has been studying the regulatory role of homeobox proteins, PHABULOSA (PHB) and PHAVOLUTA (PHV). Distribution of PHB/PHV protein is restricted by microRNA to apical embryo, triggering embryonic shoot formation. If the PHB/PHV distribution is a positional signal reflecting apical-basal axis, how do they regulate cellular growth and division patterns to establish axis? I will generate a 4D map of axis patterning, extract high quality quantitative data to develop spatial computer models, and examine the interplay between geometry and genetic regulation on axis patterning. I will also apply same approaches to study embryos in other Brassicaceae species. Such comparative developmental analysis will reveal the core mechanism of axis formation shared among these species and also provide insights into the origins of their embryonic morphological diversity.", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-08-01"], "Project_ID": ["753138"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 998 750"], "Project_Title": ["Enforced ATP wasting as a general design principle to rationally engineer microbial cell factories"], "Total_Cost": ["EUR 1 998 750"], "Country": ["Germany", "Germany"], "Project_ACR": ["StrainBooster"], "Technology_Description": "One global challenge of humanity in the 21st century is the shift from a petrochemical to a bio-based production of chemicals and fuels. An enabling technology towards this goal is metabolic engineering which uses computational and experimental methods to construct microbial cell factories with desired properties. While it has been shown that genetically engineered microorganisms can, in principle, produce a broad range of chemicals, novel approaches to improve the performance of those strains are urgently needed to develop economically viable bioprocesses.", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-05-01"], "Project_ID": ["721176"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Investigating inflammatory signaling by combining phospho- and ubiquitin proteomics with CRISPR/Cas9 technology"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["Cytokineproteomics"], "Technology_Description": "Deregulation of pro-inflammatory cytokine signalling is the underlying cause for many inflammatory diseases. Thus, understanding the molecular mechanism of cytokine signalling is necessary to develop suitable therapies. The enormous complexity of cytokine cascades has however impeded the development of new therapies. To shed more light into these intertwined signaling cascades, I plan to use a proteomics approach that allows the identification of signalling mechanisms in a multi-dimensional and unbiased fashion. The recent development of the EasyPhos protocol in the Mann laboratory will allow me to take an unprecedented look at phosphorylation events occurring in cells stimulated by single and by combinations of disease relevant cytokines. Simultaneously I will be able to detect changes in the ubiquitinome using the di-Gly enrichment strategy. By combining phosphoproteomics and ubiquitin proteomics with the CRISPR/Cas9 technology to delete and modify members of diverse signaling pathways, I will be able to analyze the role of these players and their post translational modifications in the respective signalling pathways. This study will therefore investigate the mechanisms and the relationship between phosphorylation and ubiquitylation in cytokine signalling in an unprecedented way and has the potential to result in the identification of new therapeutic strategies for the treatment of a range of inflammatory diseases.", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-03-01"], "Project_ID": ["746329"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAT ZURICH", "UNIVERSITAT ZURICH"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Towards clinical trials for a novel treatment for stroke"], "Total_Cost": ["EUR 150 000"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["NOGOPROOF"], "Technology_Description": "Stroke is the leading cause of adult disability and represents a major health problem in the EU and the Western world. Despite available acute care treatment and rehabilitation therapies, more than half of the patients remain disabled and there is a large unmet medical need accordingly. Regeneration of interrupted nerve fiber tracts and plastic \u201chardware\u201d changes in the adult mammalian central nervous system are extremely restricted, a phenomenon which represents a key reason for the low degree of recovery following CNS injuries including stroke. The molecular impediments that form the basis of this phenomenon are neurite growth inhibitory proteins expressed in central nervous system myelin, in particular the membrane protein Nogo-A which was discovered by our group. Importantly, antibodies directed against Nogo-A have been shown to induce axonal regeneration, enhance plastic circuit rearrangements and mediate significant improvements in functional recovery in rodent and non-human primate models of stroke and spinal cord injury. As recently shown in the ERC advanced grant supported the project \u2018Nogorise\u2019, almost full functional recovery was observed in rats with large strokes when anti-Nogo-A antibody treatment was followed by intensive rehabilitative training. As currently no therapy for human stroke patients beyond acute care and rehabilitation exists, there is a substantial market opportunity for the anti- Nogo-A therapy. The proposed activities within the present project aim at further establishing preclinical proof-of-concept for an anti-Nogo-A administration paradigm translatable to human stroke patients and development of human antibodies targeting Nogo-A. The expected data package will allow the critical transition from preclinical to clinical development and support the development of a comprehensive business strategy.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-03-01"], "Project_ID": ["727444"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 499 813"], "Project_Title": ["Emergent properties of cell surface glycosylation in cell-cell communication"], "Total_Cost": ["EUR 1 499 813"], "Country": ["Germany", "Germany"], "Project_ACR": ["GLYCONOISE"], "Technology_Description": "The surface of every living cell is covered with a dense matrix of glycans. Its particular composition and structure codes important messages in cell-cell communication, influencing development, differentiation, and immunological processes. The matrix is formed by highly complex biopolymers whose compositions vary from cell to cell, even between genetically identical cells. This gives rise to population noise in cell-cell communication. A second level of noise stems from glycans present on the same cell that disturb the decoding of the message by glycans binding receptors through competitive binding. Glycan-based communication is characterized by a high redundancy of both glycans and their receptors. Thus, noise and redundancy emerge as key properties of glycan-based cell-cell communication, but their extent and function are poorly understood.", "To": ["2022-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-02-01"], "Project_ID": ["716024"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Innate Immune Cell Swarms: Integrating and Adapting Single Cell and Population Dynamics in Inflamed and Infected Tissues"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["IMMUNE CELL SWARMS"], "Technology_Description": "Neutrophils are essential effector cells of the innate immune response. Intravital microscopy studies have recently changed our perspective on neutrophil tissue dynamics. They revealed swarm-like migration patterns in several models of inflammation and infection: Neutrophil populations show strikingly coordinated behavior with phases of highly directed chemotaxis and clustering at local sites of tissue damage. My previous work established that neutrophils self-amplify this swarming response by auto-signaling, which provided the first molecular basis for the collective nature of neutrophil swarms (L\u00e4mmermann et al., Nature 2013). However, we are still at the beginning of unraveling the molecular pathways behind this newly discovered phenomenon. ", "To": ["2022-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-02-01"], "Project_ID": ["715890"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Mechanisms of Regeneration Initiation"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["IniReg"], "Technology_Description": "Injury poses a key threat to all multicellular organisms. However, while some animals can fully restore lost body parts, others can only prevent further damage by mere wound healing. Which molecular mechanisms determine whether regeneration is induced or not is an unsettled fundamental question. I will use whole body regeneration, one of the most fascinating biological processes, as an experimental paradigm to identify the mechanisms of regeneration initiation. As a model organism I will employ planarians, flatworms with extraordinary plasticity that regenerate every piece of their body within a few days. I will mechanistically dissect how these animals rapidly induce an efficient regeneration program in response to tissue loss and define the key switches that determine whether a wound regenerates. Combining the astonishing regenerative abilities of planarians with new technologies I will first comprehensively describe the molecular changes occurring during the amputation response. Second, with a powerful novel assay developed in my lab - dormant fragments - that allows for the first time the separation of wounding from tissue loss in a single planarian, I will analyze the dynamics of the earliest regenerative events. Third, I will functionally characterize the regeneration-initiating signals and their target pathways combining in vivo RNAi and phenotypic assays. Fourth, with a regeneration-deficient planarian species, I will test whether the identified key regulators act as network nodes that can be utilized to rescue regeneration. Importantly, using the regenerating zebrafish fin as an experimental paradigm I will investigate conserved roles of these network nodes and validate general principles of regeneration initiation. This project will not only uncover conserved mechanisms of regeneration initiation but will also identify the switches that must be levered to induce regeneration in non-regenerating animals.", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-04-01"], "Project_ID": ["716894"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["UNIVERSITAT ZURICH"], "EU_Contribution": ["EUR 175 419,60"], "Project_Title": ["Optical Interrogation of Hippocampal Dentate Granule Circuit Dynamics in Health and Disease"], "Total_Cost": ["EUR 175 419,60"], "Country": ["Switzerland"], "Project_ACR": ["Circdyn"], "Technology_Description": "Understanding the cellular and synaptic basis of memory remains a central goal of modern neuroscience. Physical traces of memory exist as an enduring, experience-dependent change in neural activity in response to learning. In the hippocampus, a key region of the mammalian brain involved in memory formation and recall, new neurons are continually generated in the dentate gyrus (DG) where they form an integral part of the existing functional circuitry. Despite its key position in the hippocampal formation, however, the function of DG and its adult-born neurons in vivo has not been carefully investigated. Here, by applying transgenic and optogenetic approaches \u2013 including multicolour genetically encoded activity reporters \u2013 together with longitudinal two-photon imaging, we aim to study functional dynamics and plastic changes in DG in health and disorder. We propose that activity patterns in DG cell populations show activity-dependent changes during learning and construct a cellular and circuit basis for contextual memory engrams. We will also investigate how synaptic alterations in excitation-inhibition balance and defects in adult neurogenesis in DG lead to neurological disorders such as Rett syndrome.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["709288"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 239 860,80"], "Project_Title": ["Stellar Populations and Dynamics: a comprehensive IMF analysis"], "Total_Cost": ["EUR 239 860,80"], "Country": ["Germany"], "Project_ACR": ["SPanD"], "Technology_Description": "The number distribution of stars by mass in a stellar system, at birth, is given by the initial mass function (IMF). The IMF not only regulates the chemical enrichment of a galaxy, but it also determines its spectrum and the mass scale. Moreover, it is the bridge between the physics and properties of individual stars and the light that we observe from distant galaxies. Therefore, the IMF constitutes a fundamental piece in modern Astrophysics. Since the pioneers works suggested an invariant IMF in all star-forming systems, the universality of the IMF has been a common assumption in every extra-galactic study over the last 50 years. However, recent claims of IMF variations in nearby massive galaxies have challenged this standard picture. The Stellar Populations and Dynamical (SPanD) project aims to perform critical study of these IMF variations, by combining both stellar populations and dynamical techniques to derive the IMF in nearby and high-redshift objects. Given the strong dependence of most of the astronomical observables on the IMF, a comprehensive IMF analysis as proposed in SPanD is crucial to better understand our observations, and ultimately, to understand how galaxies have formed and evolved.", "To": ["2020-01-15, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-01-16"], "Project_ID": ["702607"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITAT ZURICH", "UNIVERSITAT ZURICH"], "EU_Contribution": ["EUR 1 999 090"], "Project_Title": ["Neuromorphic Electronic Agents: from sensory processing to autonomous cognitive behavior"], "Total_Cost": ["EUR 1 999 090"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["NeuroAgents"], "Technology_Description": "\"Neural networks and deep learning algorithms are currently achieving impressive state-of-the-art results. In parallel computational neuroscience has made tremendous progress with both theories of neural computation and with hardware implementations of dedicated brain-inspired computing platforms.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["724295"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITAT ZURICH", "UNIVERSITAT ZURICH"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Decoding cell-to-cell variation in genome integrity maintenance"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["DiVineGenoMe"], "Technology_Description": "Cells must ensure the integrity of their genome, and failure to do so can lead to mutations and cause disease. A sophisticated molecular network senses genomic lesions and coordinates their faithful repair with other DNA transactions, including transcription and DNA replication. Research over the last years has significantly advanced our understanding of the DNA damage response and continues to provide crucial insights that explain how cells deal with genotoxic stress to avoid malignant transformation.", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["714326"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Modelling 2D Transition Metal Dichalcogenide Heterostructures"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["MODHET"], "Technology_Description": "Although TMDs have been studied for decades, studies have been mostly limited to bulk materials. The properties of TMDs in atomically thin 2D forms can be significantly different from those in the bulk, such as the size of the band gap, the nature of the band gap (direct versus indirect), the existence of tightly-bound charged excitons. The physics of heterostructures formed by stacking different kinds of TMD layers are even more versatile and unexpected. While recent studies have experimentally demonstrated the possibility of synthesizing such novel 2D materials, the present project aims to study these new types of materials from a theoretical standpoint. We will perform state-of-the-art first-principles simulations using the most advanced exchange-correlation functionals developed in the host group for the accurate description of dynamical and charge transfer process within the time dependent density functional theory (TDDFT) as well as many-body perturbation approaches using the GW self-energy and including excitonic effects at the level of the Bethe Salpeter equation. We will also develop and implement new multi-scale algorithms in the codes needed to handle some of the tasks detailed in the project. This European Fellowship project will be hosted by a leading expert in the field, Prof. Angel Rubio of the University of the Basque Country (Spain). The project will also involve collaboration with top international experiment groups. The theoretical results acquired in this project will be used to guide and compare to experimental results with the goal of developing novel devices for future advances in nanoelectronics, photoelectronics and plasmonics. The progress of this project in exploring and understanding new physics of 2D TMDs and developing novel devices will have profound impacts on condensed matter physics, material science, as well as nano- and bio-science in the next decade.", "To": ["2019-03-02, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-03-03"], "Project_ID": ["709382"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 257 860,80"], "Project_Title": ["Characterizing Function Genetic Variants Linking Immunity and Psychiatric Disorders"], "Total_Cost": ["EUR 257 860,80"], "Country": ["Germany"], "Project_ACR": ["IMAGENE"], "Technology_Description": "Understanding genetic risk for disease is one of the major goals in human genetics. Genome-wide association studies (GWAS) have identified thousands of genetic variants associated with complex human diseases, the majority of them locating in regulatory regions outside of genes. The identification of functional regulatory variants underlying such GWAS associations and understanding their pattern of activity is the key for understanding biological processes behind each genetic association to disease \u2013 and without such understanding, targeted interventions and drugs to affect the relevant pathways are not possible.", "To": ["2020-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-08-01"], "Project_ID": ["706636"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 494 963"], "Project_Title": ["Interaction Dynamics of Bacterial Biofilms with Bacteriophages"], "Total_Cost": ["EUR 1 494 963"], "Country": ["Germany", "Germany"], "Project_ACR": ["BIOFAGE"], "Technology_Description": "Biofilms are antibiotic-resistant, sessile bacterial communities that occupy most moist surfaces on Earth and represent a major mode of bacterial life. Another common feature of bacterial life is exposure to viral parasites (termed phages), which are a dominant force in bacterial population control throughout nature. Surprisingly, almost nothing is known about the interactions between biofilm-dwelling bacteria and phages. This proposal is designed to fill this gap using a combination of novel methodology, experimental systems, and mathematical modeling. We have recently developed a new microscopic imaging technique that allows us to image and track all individual cells and their gene expression inside biofilms. First, we will use this technique for tracking the population dynamics of bacteria and phages within biofilms at single cell resolution. By genetically manipulating bacterial hosts and their phages, and by varying environmental conditions, we will investigate the fundamental biological and physical determinants of phage spread within biofilm communities. Second, we will study how biofilms respond to phage attack on both intra-generational and evolutionary time scales, focusing in particular on proximate response mechanisms and the population dynamics of phage-resistant and phage-susceptible cells as a function of biofilm spatial structure. Lastly, we will combine our novel insights to engineer phages that manipulate the composition of biofilm communities, either by subtraction of particular bacterial species or by addition of novel phenotypes to existing biofilm community members. Altogether, the proposed research promises to uncover the major mechanistic and evolutionary elements of biofilm-phage interactions. This combined work will greatly enrich our knowledge of microbial ecology and motivate novel strategies for bacterial biofilm control, an increasingly urgent priority in light of widespread antibiotic resistance.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-01-01"], "Project_ID": ["716734"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 499 437,50"], "Project_Title": ["Computer-Assisted Language Comparison: Reconciling Computational and Classical Approaches in Historical Linguistics"], "Total_Cost": ["EUR 1 499 437,50"], "Country": ["Germany", "Germany"], "Project_ACR": ["CALC"], "Technology_Description": "By comparing the languages of the world, we gain invaluable insights into human prehistory, predating the appearance of written records by thousands of years. The traditional methods for language comparison are based on manual data inspection. With more and more data available, they reach their practical limits. Computer applications, however, are not capable of replacing experts' experience and intuition. In a situation where computers cannot replace experts and experts do not have enough time to analyse the massive amounts of data, a new framework, neither completely computer-driven, nor ignorant of the help computers provide, becomes urgent. Such frameworks are well-established in biology and translation, where computational tools cannot provide the accuracy needed to arrive at convincing results, but do assist humans to digest large data sets. ", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-04-01"], "Project_ID": ["715618"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 836 070"], "Project_Title": ["Microstructured Topological Materials: A novel route towards topological electronics"], "Total_Cost": ["EUR 1 836 070"], "Country": ["Germany", "Germany"], "Project_ACR": ["MiTopMat"], "Technology_Description": "Topological semi-metals such as Cd3As2 or TaAs are characterized by two bands crossing at isolated points in momentum space and a linear electronic dispersion around these crossing points. This linear dispersion can be mapped onto the Dirac- or Weyl-Hamiltonian, describing relativistic massless fermions, and thus relativistic phenomena from high-energy physics may appear in these materials. For example, the chirality, \u03c7=\u00b11, is a conserved quantity for massless fermions, separating the electrons into two distinct chiral species. A new class of topological electronics has been proposed based on chirality imbalance and chiral currents taking the role of charge imbalance and charge currents in electronics. Such devices promise technological advances in speed, energy efficiency, and quantum coherent processes at elevated temperatures.", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-04-01"], "Project_ID": ["715730"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 443 000"], "Project_Title": ["Connecting SOLar and stellar Variabilities"], "Total_Cost": ["EUR 1 443 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["SOLVe"], "Technology_Description": "The proposed project aims at answering four general questions of high scientific importance:", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-01-01"], "Project_ID": ["715947"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["UNIVERSITAT ZURICH", "UNIVERSITAT ZURICH"], "EU_Contribution": ["EUR 1 474 133"], "Project_Title": ["Welfare state politics under pressure: Identifying priorities, trade-offs and reform opportunities among citizens, political and economic elites"], "Total_Cost": ["EUR 1 474 133"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["WELFAREPRIORITIES"], "Technology_Description": "In times of austerity, the politics of the welfare state involve tough choices and even trade-offs: whose risks should benefit from social solidarity in a context of shrinking resources? Should the welfare state prioritize the needs of the elderly or those of the young? Those of people in the workforce or outside of the workforce? Of natives or of immigrants? ", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["716075"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 892 500"], "Project_Title": ["Fundamentals of ASymmeTric Organo-CATalysis"], "Total_Cost": ["EUR 1 892 500"], "Country": ["Germany", "Germany"], "Project_ACR": ["FASTO-CAT"], "Technology_Description": "For most biologically relevant molecules their chirality is decisive for their function. Within the last two decades asymmetric organo-catalysis has emerged as an environmental benign, metal-free alternative for conventional asymmetric transition metal catalysis. The organo-catalysts, which employ catalyst-substrate interaction motifs commonly found for enzymes, yield unprecedented enantiomeric excesses. Despite the success of these organo-chemical routes, remarkably little is known about the molecular details of the interaction between the catalyst and the substrate. Consequently, there is virtually no rationale method to optimize reaction conditions particularly as related to structure-function relationships. Also the exact nature of the intermediates that induce chirality has remained elusive. The aim of this proposal is to experimentally quantify the formation of reaction intermediates and the nature of intermediate induced chirality that lie at the heart of asymmetric control. This will be achieved by using a combination of advanced spectroscopic techniques. With advanced vibrational spectroscopies (ultrafast two-color and two-dimensional infrared spectroscopy), dielectric spectroscopy, and NMR spectroscopy together with quantum chemical calculations we will quantify structure-dependent interactions: binding geometry, strength of attraction, lifetime of binding, reaction intermediates, and the role of steric repulsion, probed on all timescales relevant to catalytic processes ranging from femtoseconds to seconds. Correlation of such information with the enantiomeric excess obtained in catalytic processes will allow isolating the essential ingredients for stereocontrol. Such molecular-level insights will provide fundamental parameters for optimization of reaction conditions and will initiate the transition from a trial and error approach towards a rational design of new catalytic processes.", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-04-01"], "Project_ID": ["714691"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 461 200"], "Project_Title": ["Mapping metabolic regulators at a genome-scale to switch bacteria from growth to overproduction of chemicals"], "Total_Cost": ["EUR 1 461 200"], "Country": ["Germany", "Germany"], "Project_ACR": ["MapMe"], "Technology_Description": "Metabolic engineering creates improved microbes for industrial biotechnology. Rational design of industrial microbes centres on modifications of genes with known roles in the production pathway of interest. However, genes that are unrelated to the production pathway are also known to substantially impact productivity. To date there are no methods that allow the prediction of such distal genes on a rational basis. Effects of distal genes are indirect, and mediated through regulatory interactions between metabolites and proteins, most of which are currently unknown even in the well-studied microbe Escherichia coli. The lack of knowledge of metabolite-protein interactions thus effectively prohibits systematic exploration of distal regulatory relationships, with the consequence that models used to predict metabolic engineering targets are severely limited and rarely applied in industrial biotechnology. Previously, we used small-scale metabolic models and metabolomics to infer metabolite-protein interactions in specific pathways. In this project we propose a novel genome-wide endeavor to map metabolite-protein interactions across the entire metabolic network. For this purpose, we will use the recently developed CRISPR interference system to quantitatively perturb >900 single metabolic genes in E. coli. Combining the metabolomics data of these >900 gene perturbations with a genome-scale metabolic model will enable us to infer functionally relevant metabolite-protein interactions. Finally, we will apply this knowledge to the model-guided metabolic engineering of superior E. coli strains. Specifically, we want E. coli to cease growth upon induction and focus all its metabolic resources towards synthesis of succinic acid. This controlled uncoupling of growth from overproduction on a rational basis will break new grounds in metabolic engineering and opens up novel applications in industrial biotechnology.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-01-01"], "Project_ID": ["715650"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["UNIVERSITAT ZURICH", "UNIVERSITAT ZURICH"], "EU_Contribution": ["EUR 1 970 000"], "Project_Title": ["Wiring up the SomatoSensory Cortex"], "Total_Cost": ["EUR 1 970 000"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["InterWiring"], "Technology_Description": "Understanding how the mammalian brain network acquires its ability during development to process information and interact with the environment is one of the fundamental challenges in modern biology.", "To": ["2021-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-11-01"], "Project_ID": ["679175"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["UNIVERSITAT ZURICH", "UNIVERSITAT ZURICH"], "EU_Contribution": ["EUR 1 994 981"], "Project_Title": ["Bacterial cooperation at the individual cell level"], "Total_Cost": ["EUR 1 994 981"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["BactInd"], "Technology_Description": "All levels of life entail cooperation and conflict. Genes cooperate to build up a functional genome, which can yet be undermined by selfish genetic elements. Humans and animals cooperate to build up societies, which can yet be subverted by cheats. There is a long-standing interest among biologists to comprehend the tug-of-war between cooperation and conflict. Recently, research on bacteria was successful in identifying key factors that can tip the balance in favour or against cooperation. Bacteria cooperate through the formation of protective biofilms, cell-to-cell communication, and the secretion of shareable public goods. However, the advantage of bacteria being fast replicating units, easily cultivatable in high numbers, is also their disadvantage: they are small and imperceptible, such that measures of cooperation typically rely on averaged responses across millions of cells. Thus, we still know very little about bacterial cooperation at the biological relevant scale: the individual cell level. Here, I present research using the secretion of public goods in the opportunistic human pathogen Pseudomonas aeruginosa, to tackle this issue. I will explore new dimensions of bacterial cooperation by asking whether bacteria engage in collective-decision making to find optimal group-level solutions; whether bacteria show division of labour to split up work efficiently; and whether bacteria can distinguish between trustworthy and cheating partners. The proposed research will make two significant contributions. First, it will reveal whether bacteria engage in complex forms of cooperation (collective decision-making, division of labour, partner recognition), which have traditionally been associated with higher organisms. Second, it will provide insights into the evolutionary stability of cooperation \u2013 key knowledge for designing therapies that interfere with virulence-inducing public goods in infections, and the design of stable public-good based remediation processes.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["681295"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 997 853"], "Project_Title": ["Dissecting the (epi)genetic origins of phenotypic variation and metabolic disease susceptibility"], "Total_Cost": ["EUR 1 997 853"], "Country": ["Germany", "Germany"], "Project_ACR": ["DismantlingNoise"], "Technology_Description": "Current estimates place the prevalence of obesity beyond 1 billion by the year 2030. As a critical risk factor for heart disease, diabetes and stroke, obesity represents one of the chief socio-economic challenges of our day. While studies have mapped a genetic framework for understanding obesity, the etiological contribution of several regulatory layers, and in particular epigenetic regulation, remain poorly understood. A perfect example, we know that isogenic C57Bl6/J mice can vary by as much as 100% in body weight upon high fat feeding; currently, we have no mechanistic explanation for the emergence of such phenotypic variation. Here, I propose three aims dedicated towards understanding the (epi)genetic control of phenotypic variation and disease susceptibility. First, we will catalogue epigenome and phenome variation to an unprecedented depth and resolution in the isogenic context. Next, we will examine two completely novel models of epigenetically sensitized bi-stable obesity and thus begin a mechanistic dissection of phenotypic variation. Finally, we will map a series of gene-gene and gene-environment epistasis interactions including eight models of developmental plasticity and approximately a dozen chromatin regulator mutants. The latter epistasis matrix will identify the molecular mechanisms that trigger, amplify and buffer phenotypic variation and stochastic obesity in mice. The functional (epi)phenomics approach is unique. It builds the first unbiased framework against which to understand developmental plasticity and phenotypic variation, and at the same time generates powerful resources for disease researchers worldwide.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-01-01"], "Project_ID": ["682679"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 2 498 013"], "Project_Title": ["Rules of self-organization and reengineering of liver tissue"], "Total_Cost": ["EUR 2 498 013"], "Country": ["Germany", "Germany"], "Project_ACR": ["RULLIVER"], "Technology_Description": "We want to understand the rules of self-organization underlying tissue structure and function. To address this problem, we have chosen the mouse liver with its complex apico-basal polarity of hepatocytes and its unique 3D tissue organization. We aim at identifying the rules of self-organization of liver tissue and their implementation at the molecular level. Our ultimate goal is to demonstrate that it is possible to reengineer liver tissue structure. The first aim will be to develop a digital geometrical model of liver tissue, i.e. an accurate 3D digital representation of the cells, forming the tissue and their sub-cellular components, in the developing, adult and regenerating liver, and unravel the principles for how the cells are organized to generate liver cell architecture. In aims 2 and 3, we will identify the molecular mechanisms underlying such geometrical rules. In particular, the second aim will be to characterize the molecular mechanisms responsible for hepatocyte cell polarity and predictably modify cell organization in vitro. The third aim will consist of introducing genetic perturbations to alter hepatocyte cell organization (cell polarity) and cell-cell interactions to predictably modify the structure and function of liver tissue. The fourth aim will be to develop a physical model of liver tissue self-assembly and organization. The project is ambitious as it aims to understand the rules of tissue organization in 3D in a mammalian organ to such an extent that it is possible to make predictions of tissue response to genetic perturbations and reengineer it to modify its structural and functional properties.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2016-10-01"], "Project_ID": ["695646"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 2 640 632,89"], "Project_Title": ["Electron-lattice-spin correlations and many-body phenomena in 2D semiconductors and related heterostructures"], "Total_Cost": ["EUR 2 640 632,89"], "Country": ["Germany", "Germany"], "Project_ACR": ["FLATLAND"], "Technology_Description": "Two-dimensional crystalline materials exhibit exceptional physical properties and offer fascinating potential as fundamental building blocks for future two-dimensional electronic and optoelectronic devices. Transition metal dichalcogenides (TMDCs) are of particular interest as they show a variety of many-body phenomena and correlation effects. Key properties are: i) additional internal degrees of freedom of the electrons, described as valley pseudospin and layer pseudospin, ii) electronic many-body effects like strongly-bound excitons and trions, and iii) electron-lattice correlations like polarons. While these phenomena represent intriguing fundamental solid state physics problems, they are of great practical importance in view of the envisioned nanoscopic devices based on two-dimensional materials. ", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2016-10-01"], "Project_ID": ["682843"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Uneven lives: female economy, migration patterns and citizenship in Early Modern Italy"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["FemEcoMig"], "Technology_Description": "FemEcoMig aims to study the connections between migration patterns and female property, work and social networks in Early Modern Italy: it focuses on domestic and international migrations and on female migrants (and their families) who moved to the duchy of Savoy-Piedmont during the period 1650-1800. The project aims to change the common narrative on the history of migration by bringing into the topic a range of historiographical problems that are often considered characteristic of the history of women. It will inquire into the role women's paid and unpaid work and into the use of female property in settlement paths; it will also tackle the extent of female social networks and their use to access to urban resources. The second objective is to analyse the connections between female migration and the achievement of naturalisation. This section will investigates foreign women applying for naturalisation and the reasons for their application. The project will tackle the contents of the grant, and the conditions in which citizenship was enacted and will inquire into the links between migration and settlement paths, economic activities and family strategies.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["703737"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 2 250 000"], "Project_Title": ["Development and Evolution of Colour Patterns in Danio species"], "Total_Cost": ["EUR 2 250 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["DanioPattern"], "Technology_Description": "Colour patterns are prominent features of many animals and have important functions in communication such as camouflage, kin recognition and mate selection. Colour patterns are highly variable and evolve rapidly leading to large diversities even within a single genus. As targets for natural as well as sexual selection, they are of high evolutionary significance. The zebrafish (Danio rerio), a vertebrate model organism for the study of development and disease, displays a conspicuous pattern of alternating blue and golden stripes on the body and on the anal- and tailfins. Mutants with spectacularly altered patterns have been analysed, and novel approaches in lineage tracing have provided first insights into the cellular and molecular basis of colour patterning. These studies revealed that the mechanisms at play are novel and of fundamental interest to the biology of pattern formation. Closely related Danio species have very divergent colour patterns in body and fins offering the unique opportunity to study development and evolution of colour patterns in vertebrates building on the thorough analysis of one model species. Our research in zebrafish will explore the basis of direct interactions between chromatophores mediated by channels and junctions. We will investigate the divergent mode of stripe formation in the fins and the molecular influence of the cellular environment on chromatophore interactions. In closely related Danio species, we will investigate the cellular interactions during pattern formation. We will analyse transcriptomes and genome sequences to identify candidate genes providing the molecular basis for pigment pattern diversity. These candidate genes will be tested by creating mutants and exchanging allelic variants using the CRISPR/Cas9 system. The work will lay the foundation to understand not only the genetic basis of variation in colour pattern formation between Danio species, but also the evolution of biodiversity in other vertebrates.", "To": ["2021-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2016-11-01"], "Project_ID": ["694289"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 2 350 000"], "Project_Title": ["Genome sequences from extinct hominins"], "Total_Cost": ["EUR 2 350 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["100 Archaic Genomes"], "Technology_Description": "Neandertals and Denisovans, an Asian group distantly related to Neandertals, are the closest evolutionary relatives of present-day humans. They are thus of direct relevance for understanding the origin of modern humans and how modern humans differ from their closest relatives. We will generate genome-wide data from a large number of Neandertal and Denisovan individuals from across their geographical and temporal range as well as from other extinct hominin groups which we may discover. This will be possible by automating highly sensitive approaches to ancient DNA extraction and DNA libraries construction that we have developed so that they can be applied to many specimens from many sites in order to identify those that contain retrievable DNA. Whenever possible we will sequence whole genomes and in other cases use DNA capture methods to generate high-quality data from representative parts of the genome. This will allow us to study the population history of Neandertals and Denisovans, elucidate how many times and where these extinct hominins contributed genes to present-day people, and the extent to which modern humans and archaic groups contributed genetically to Neandertals and Denisovans. By retrieving DNA from specimens that go back to the Middle Pleistocene we will furthermore shed light on the early history and origins of Neandertals and Denisovans.", "To": ["2021-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2016-11-01"], "Project_ID": ["694707"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Modelling of Generic Extreme mass-ratio inspirals"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["MoGEs"], "Technology_Description": "Inspiralling binaries of compact objects are a promising source of gravitational waves (GWs) in the upcoming era of GW astronomy. The MoGEs project proposes to take the next step in modelling the evolution of compact binaries using the gravitational self-force (GSF) formalism. Until now, the linear-in-mass-ratio GSF has only been calculated under the simplifying assumptions of non-spinning, circular, and/or equatorial binaries. MoGEs will, for the first time, calculate linear-in-mass-ratio GSF including all effects of spin, eccentricity and inclination.", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-03-01"], "Project_ID": ["705229"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 2 181 250"], "Project_Title": ["Small - and nano - scale soft phononics"], "Total_Cost": ["EUR 2 181 250"], "Country": ["Germany", "Germany"], "Project_ACR": ["Smartphon"], "Technology_Description": "Colloid and polymer science allows the engineering of acoustic and optical material functionalities of hierarchical structures on various length scales commensurate with and well below the characteristic length scales of phonons and photons. Periodic structures act as both hypersonic phononic and visible light photonic crystals (phoxonics). We recently extended the decade-old field to hypersonic phononics. Many important questions in this young field are just being raised and require new conceptual and technical approaches to address them.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2016-09-01"], "Project_ID": ["694977"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 505 000"], "Project_Title": ["Imaging synaptic plasticity by ultra-high field magnetic resonance spectroscopy in health and psychiatric disease"], "Total_Cost": ["EUR 1 505 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["SYNAPLAST MR"], "Technology_Description": "A large number of psychiatric disorders (major and bipolar depression (MDD / BD), schizophrenia, obsessive-compulsive disorder (OCD), addiction, anxiety, attention deficit hyperactivity syndrome (ADHS), posttraumatic stress disorder (PTSD), autism) lack objective criteria for primary diagnosis, early differential diagnosis with regard to subtypes in treatment response and disease progression or effective therapy monitoring. Hence, the search for relevant biomarkers is of high importance. This proposal suggests the development of novel methodology for highly spatially and temporally resolved imaging of disease effects on neurotransmission, membrane processes related to synaptic plasticity and brain energy metabolism in psychiatric disorders and the acute and chronic impact of related pharmacological treatment in the human brain. To that, the advantages of a unique 9.4 T whole body human magnetic resonance imaging (MRI) system for 1H, 31P and 13C magnetic resonance spectroscopic imaging shall be exploited. Highly innovative enabling MRI technology including parallel transmission, very high order B0 shimming, a real time field stabilization and motion correction approach along with the principles of advanced encoding and non-Fourier image reconstruction shall ensure high data quality. Next to obtaining 20 novel image contrasts based on steady state metabolite concentrations, the ultimate goal of the proposed research is to enable functional spectroscopic imaging in the entire human brain in order to investigate adaptation of neurotransmission and brain metabolism to environmental stimuli as well as the impact of acute pharmacological intervention. Finally, the spatially and temporally resolved metabolic imaging technology shall be used for investigation of patients with major depressive disorder to reveal novel biomarkers relevant for diagnostics and patient stratification.", "To": ["2021-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2016-07-01"], "Project_ID": ["679927"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["UNIVERSITAT ZURICH", "UNIVERSITAT ZURICH"], "EU_Contribution": ["EUR 1 700 000"], "Project_Title": ["Developing multi-modality nanomedicines for targeted annotation of oncogenic signaling pathways"], "Total_Cost": ["EUR 1 700 000"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["NanoSCAN"], "Technology_Description": "Spatial and temporal changes in the underlying biochemistry of cancer control disease progression and response/resistance to treatment. Developing methods to detect changes in oncogenic signaling at an early stage is vital to further our understanding of cancer, and will advance the next generation of anti-cancer therapies. Nanomedicine is the medical application of nanotechnology to diagnose or treat disease. In light of the recent introduction of tools like Positron Emission Tomography/Magnetic Resonance Imaging (PET/MRI) scanners, there is now a new opportunity to develop hybrid imaging protocols that can simultaneously take advantage of the functional and anatomic information available from PET/MRI to address changes in oncogenic signaling pathways. The work outlined in this interdisciplinary ERC Project is designed to advance new chemistry and imaging methods to measure changes in oncogenic signaling in various cancers before, during and after treatment using PET/MRI. The long-term goals are to expand the scope and utility of radiolabelled nanomedicines as dual-modality PET/MRI probes for detecting changes in oncogenic signaling in various cancers and develop efficient methods for translating new technologies to the clinic. Successful completion of this ERC Project has the potential to transform personalised clinical management of cancer patients via advanced PET/MRI detection of oncogenic signaling processes.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["676904"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 2 500 000"], "Project_Title": ["Blood Vessel Development and Homeostasis: Identification and Functional Analysis of Genetic Modifiers"], "Total_Cost": ["EUR 2 500 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["ZMOD"], "Technology_Description": "The vascular system is a complex network of blood vessels that transports gases, nutrients and hormones throughout the organism. Most blood vessels that form during development and growth arise by the sprouting of new capillaries from pre-existing vessels, a process termed angiogenesis. An imbalance in angiogenesis contributes to the pathogenesis of numerous disease states: insufficient angiogenesis limits tissue recovery in ischemic disease, whereas stimulation of angiogenesis by cancer cells promotes tumor vascularization and growth. Angiogenesis inhibitors are already in clinical use for anti-tumor therapy; however, multiple reports of resistance are calling for the identification of additional targets. Furthermore, vascular malformations are a significant cause of morbidity and mortality. While the genetic basis for some vascular malformations is known, many genetic factors, including modifiers that affect the age-of-onset and severity of phenotypes, remain to be identified. Identifying modifier genes is important not only to fully assess genetic risk, but also to provide novel targets for therapy; however, identifying modifier genes has proven challenging. We recently uncovered a novel and simple way to identify modifier genes. By investigating gene and protein expression differences between knockout (mutant) and knockdown (antisense treated) zebrafish embryos, we found that mutations in specific genes, including some encoding angiogenic factors, lead to the upregulation of compensating (i.e., modifier) genes while knocking down these same genes does not. We hypothesize that the modifier genes identified through this approach in zebrafish also play important roles in humans. Thus, we will use this simple strategy to identify new genes that regulate vascular formation and homeostasis, and subsequently analyze their function in zebrafish as well as in mammalian models, as they are likely to play key roles in vascular development and disease.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2016-10-01"], "Project_ID": ["694455"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 2 495 000"], "Project_Title": ["Physics of Star Formation and Its Regulation"], "Total_Cost": ["EUR 2 495 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["PhysSF"], "Technology_Description": "In the past decade we learned when and where stellar mass was built up in galaxies through cosmic time, now we must understand the physical causes in order to answer `How do galaxies form and evolve?\u2019. This ERC project is designed to greatly advance our understanding of the physics of the star formation (SF) process and its regulation in typical star forming galaxies. The ERC project consists of 2 complementary parts: (A) an unparalleled characterization of the SF process in nearby galaxies through full exploitation of the revolutionary capabilities of the latest millimeter interferometers (ALMA) and optical integral field units (MUSE). This study will constrain the key physical parameters for the SF process on only 50pc scales - the scale of large HII regions and their predecessors, giant molecular clouds. At this crucial scale, the MUSE-ALMA-HST Survey will provide a characterization of the SF history, stellar/gaseous surface densities, metallicities of stars and gas, the stellar radiation field, extinction, and stellar/gas kinematics, and thus uncover the physical conditions that control and regulate the SF process. Part (B) will place the results of part (A) in a cosmological context, by characterizing key galaxy quantities (e.g., gas mass fraction, specific SF rates, gas depletion times) in fully representative galaxy samples after (z<3) and before (z>3) the peak epoch of cosmic star formation density. In addition to providing the critically needed constraints on the conditions that govern the SF process, this ERC project will provide the observational benchmark for state-of-the art galaxy simulations and models. The PI is internationally recognized as a leader in SF studies in nearby and distant galaxies, and has successfully led large international collaborations that strongly shaped our current understanding of the SF process. Through her track record and access to the required data, the PI is uniquely positioned to successful lead this ambitious program.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2016-10-01"], "Project_ID": ["694343"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 2 496 250"], "Project_Title": ["Structural biology of mammalian transcription regulation"], "Total_Cost": ["EUR 2 496 250"], "Country": ["Germany", "Germany"], "Project_ACR": ["TRANSREGULON"], "Technology_Description": "The regulation of gene transcription by RNA polymerase (Pol) II underlies cell differentiation and organism development, and its dysregulation causes many cancers. Transcription regulation occurs during initiation, when Pol II assembles with initiation factors on promoter DNA, but also during mRNA chain elongation, when Pol II pauses near the promoter before it restarts upon activation. Our previous ERC Advanced Grant \u2018TRANSIT\u2019 enabled us to provide molecular insights into yeast Pol II initiation and its regulation by the Mediator coactivator complex (Plaschka et al., Nature 2015; Sainsbury et al., Nature 2012, Lariviere et al, Nature 2012). Here, with our new proposal \u2018TRANSREGULON\u2019 we wish to open a new frontier and provide the structural basis for mammalian Pol II regulation during elongation. We will use an integrated structural biology approach combining X-ray crystallography, cryo-electron microscopy, and crosslinking, to obtain the first atomic structure of a mammalian Pol II enzyme (aim 1), the structure of the negative elongation factor NELF (aim 2), which is required for promoter-proximal pausing by mammalian Pol II, and the threedimensional architecture of the promoter-proximally paused Pol II complex (aim 3) containing the multiprotein pausing factors NELF and DSIF, and eventually also the pause release factor p-TEFb. This ground-breaking work will make the transition from yeast to human structural biology of transcription, will provide the molecular basis for a central mechanism of cellular regulation, and will advance structural biology methods for dissecting large and transient mammalian multicomponent complexes.", "To": ["2021-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2016-07-01"], "Project_ID": ["693023"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Understanding the molecular basis of stochastic bi-stable obesity"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["EPOC"], "Technology_Description": "Substantial evidence indicates that even when genetically matched, we are not created equal. The mechanisms underlying such non-Mendelian phenotype variation are sufficient to elicit complex disease but remain unknown. ", "To": ["2018-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2016-12-01"], "Project_ID": ["707123"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 2 469 136"], "Project_Title": ["Absolute Spin Dynamics in Quantum Materials"], "Total_Cost": ["EUR 2 469 136"], "Country": ["Germany", "Germany"], "Project_ACR": ["ABSOLUTESPIN"], "Technology_Description": "One of the greatest challenges in exploiting the electron spin for information processing is that it is not a conserved quantity like the electron charge. In addition, spin lifetimes are rather short and correspondingly coherence is quickly lost. This challenge culminates in the coherent manipulation and detection of information from a single spin. Except in a few special systems, so far, single spins cannot be manipulated coherently on the atomic scale, while spin coherence times can only be measured on spin ensembles. A new concept is needed for coherence measurements on arbitrary single spins. Here, the principal investigator (PI) will combine a novel time- and spin-resolved low-temperature scanning tunneling microscope (STM) with the concept of pulsed electron paramagnetic resonance. With this unique and innovative setup, he will be able to address long-standing problems, such as relaxation and coherence times of arbitrary single spin systems on the atomic scale as well as individual spin interactions with the immediate surroundings. Spin readout will be realized through the detection of the absolute spin polarization in the tunneling current by a superconducting tip based on the Meservey-Tedrow-Fulde effect, which the PI has recently demonstrated for the first time in STM. For the coherent excitation, a specially designed pulsed GHz light source will be implemented. The goal is to better understand the spin dynamics and coherence times of single spin systems as well as the spin interactions involved in the decay mechanisms. This will have direct impact on the feasibility of quantum spin information processing with single spin systems on different decoupling surfaces and their scalability at the atomic level. A successful demonstration will enhance the detection limit of spins by several orders of magnitude and fill important missing links in the understanding of spin dynamics and quantum computing with single spins.", "To": ["2021-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2016-07-01"], "Project_ID": ["681164"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["REalistic Simulations and ObservationaL Validation of small-scale Energy channels on the Sun"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["RESOLVE"], "Technology_Description": "Sun-like stars possess magnetically confined, upper atmospheres. These coronae have temperatures of several million degrees and thus are much hotter than the underlying stellar surfaces (photospheres) which have temperatures of the order of 6000 degrees. The coronae are hotter than the photospheres because magnetic energy is generated by convective motions beneath the stellar surface and then transported through the photosphere into the corona where it is dissipated. The key to understanding the heating of the corona is to determine how, and at which spatial and temporal scales, energy is being transported into the stellar atmosphere. Both theory and simulations suggest that a substantial fraction of the energy transfer happens at spatial scales smaller than those currently observationally resolvable. The main goal of the proposed research is to bridge this gap between what we expect from theory and what we can observe. The proposed research will use numerical simulations to characterize the energy flux and look for its (spectropolarimetric) signature. This signature will then be used to create maps of the energy flux on the actual Sun using the highest-resolution observations (50-70 km) which are available: those from the 1-meter Sunrise balloon-borne observatory, and the 1.5-meter GREGOR, Europe's largest solar telescope. We will validate the diagnostics by comparing these maps of the observed energy flux into the solar atmosphere with co-spatial observations of the hot plasma structures seen in the upper atmosphere. Understanding the energy transfer combines the strengths of advanced simulations and the unprecedented observations as well as combining the expertise of world-leading solar groups in Germany and Spain. This research will have a major impact on our understanding of the heating of upper atmosphere. It is the ideal project and set of collaborations to further the experienced researcher's scientific career.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-01-01"], "Project_ID": ["707837"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITAT ZURICH"], "EU_Contribution": ["EUR 187 419,60"], "Project_Title": ["The role of the iron-sulpur cluster in human DNA polymerase delta"], "Total_Cost": ["EUR 187 419,60"], "Country": ["Switzerland"], "Project_ACR": ["TRISCPOL"], "Technology_Description": "The human genome is composed of 3 billion base pairs of DNA that are replicated prior to every cell division with an astonishing accuracy. High-fidelity replication is necessary to maintain genome stability, and hence to avoid premature ageing and cancer. This project aims at understanding the role of the iron-sulphur (FeS) cluster in human DNA polymerase delta (Pol \u03b4), one of the major replicases.", "To": ["2018-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["707299"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 239 860,80"], "Project_Title": ["Attention and memory components in every-day cognitive problems in aging"], "Total_Cost": ["EUR 239 860,80"], "Country": ["Germany"], "Project_ACR": ["MEMORAGE"], "Technology_Description": "Older individuals experience problems in many every-day tasks, due to age-related decline in cognitive functions. Cognitive frailty is a societal and economical challenge, as it affects elderly\u2019s quality of life and need for care. To understand, and counteract, cognitive difficulties, we need to be able to measure them. Basic research has revealed essential knowledge on age-related cognitive and neuronal changes. However, the correlation between laboratory task performance, brain alterations, and experienced difficulties in daily life is imperfect. In the realms of attention and memory, the problem may lie in the tasks we use. Most laboratory tasks are made of brief trial structures, which is useful to isolate specific process components. Real world tasks, while built of smaller components, are complex and extend over time. This project presents a multi-method neuro-cognitive approach to unravel sources of older individuals\u2019 deficit. The research is based on leading theoretical models and includes behavioral data modeling, eye-movement and EEG data analyses. At my TC host, Wolfe\u2019s Visual Attention Lab (Harvard Medical School), we will create new extended hybrid search and foraging tasks that enable us not only to look at the small components, but also to analyze how they interact over time, and how they relate to age-specific daily problems. At Bundesen\u2019s Center for Visual Cognition (University of Copenhagen), the new knowledge will be integrated into the computational \u201cTheory of Visual Attention\u201d framework and the model-based assessment procedure. Our aim is to advance the theoretical knowledge about attention and memory and improve cognitive assessment products. Commercialization of the newly developed tests will be exploited together with the industrial partner Cambridge Cognition, a company producing cognitive assessment tools. The outcome will be relevant to the development of technology, products, and strategies to meet the needs of our aging population.", "To": ["2020-02-29, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-03-01"], "Project_ID": ["702483"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 330 625"], "Project_Title": ["Gravity, Inflation, and Galaxies: Fundamental Physics with Large-Scale Structure"], "Total_Cost": ["EUR 1 330 625"], "Country": ["Germany", "Germany"], "Project_ACR": ["GrInflaGal"], "Technology_Description": "Over the past two decades, a data-driven revolution has occurred in our understanding of the origin and evolution of our Universe and the structure within it. During this period, cosmology has evolved from a speculative branch of theoretical physics into precision science at the intersection of gravity, particle- and astrophysics. Despite all we have learned, we still do not understand why the Universe accelerates, and how the structure in the Universe originated. Recent breakthrough research, with leading contributions by the PI of this proposal, has shown that we can make progress on these questions using observations of the large-scale structure and its tracers, galaxies. This opens up a fascinating, new interdisciplinary research field: probing Gravity and Inflation with Galaxies. The goal of the proposed research is to first, probe our theory of gravity, General Relativity, on cosmological scales. Second, it aims to shed light on the origin of the initial seed fluctuations out of which all structure in the Universe formed, by constraining the physics and energy scale of inflation. While seemingly unrelated, the main challenge in both research directions consists in understanding the nonlinear physics of structure formation, which is dominated by gravity on scales larger than a few Mpc. By making progress in this understanding, we can unlock a rich trove of information on fundamental physics from large-scale structure. The research goals will be pursued on all three fronts of analytical theory, numerical simulations, and confrontation with data. With space missions, such as Planck and Euclid, as well as ground-based surveys delivering data sets of unprecedented size and quality at this very moment, the proposed research is especially timely. It will make key contributions towards maximizing the science output of these experiments, deepen our understanding of the laws of physics, and uncover our cosmological origins.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2016-09-01"], "Project_ID": ["678652"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["THE UNIVERSITY OF EDINBURGH", "THE UNIVERSITY OF EDINBURGH", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 2 499 331"], "Project_Title": ["An integrated approach to understanding the impact of de novo mutations on the mammalian genome"], "Total_Cost": ["EUR 2 499 331"], "Country": ["United Kingdom", "United Kingdom", "Germany"], "Project_ACR": ["DENOVOMUT"], "Technology_Description": "Understanding the process of spontaneous mutation is fundamental for understanding the genetic basis of quantitative variation, the threat posed by declining population size in conservation biology and the distribution of nucleotide variation in the genome. I will address these and other unanswered questions concerning the evolutionary impact of spontaneous mutation using the house mouse as a model system. With the first, highly replicated mutation accumulation (MA) experiment in any vertebrate, I will study the impact of mutation accumulation on fitness and other quantitative traits and on genomic variation. I will pay particular attention to the effects of mutations in the heterozygous state, since this is important for resolving two important questions: 1. The threat posed by deleterious mutation accumulation in humans, where natural selection has weakened in many populations, and in endangered species, where declining effective population size has made selection less effective, and 2. The extent by which new mutations sustain response to artificial selection. By characterizing many thousands of mutation events by genome sequencing of MA lines and wild mice, I will determine the molecular spectrum and the factors explaining mutation rate variation across the genome. I will exploit this new knowledge to address the long-unanswered question of the causes of correlations between nucleotide diversity and the recombination rate and the density of conserved genomic elements. I will develop new approaches, incorporating the simultaneous action of mutation, selection, drift and recombination, to determine the contributions of background selection and selective sweeps to variation in nucleotide diversity, and to quantify the contributions of coding and noncoding mutations to fitness variation. ", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-01-01"], "Project_ID": ["694212"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["UNIVERSITAT ZURICH", "UNIVERSITAT ZURICH"], "EU_Contribution": ["EUR 1 499 755"], "Project_Title": ["How Infection History Shapes the Immune System: Pathogen-induced Changes in Regulatory T Cells"], "Total_Cost": ["EUR 1 499 755"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["Immune Regulation"], "Technology_Description": "Studying host-pathogen interactions by focusing on the interaction of a single pathogen with the host has defined our understanding of these events and the insights gained form the basis for the therapeutic and vaccination strategies we use today. However, people become infected with multiple pathogens throughout their lifetime, at times even simultaneously. Still, it is largely unknown how the immune response to one pathogen alters the body\u2019s ability to respond to a second infectious agent or the susceptibility to autoimmunity or cancer. This project will address this question by focusing on infection-induced changes in regulatory T cells (Tregs) as they may lead to biased suppression and changes in the nature of subsequent immune responses.", "To": ["2021-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["677200"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 2 418 750"], "Project_Title": ["Solar magnetic field and its influence on solar variability and activity"], "Total_Cost": ["EUR 2 418 750"], "Country": ["Germany", "Germany"], "Project_ACR": ["SOLMAG"], "Technology_Description": "For life on Earth, the Sun is the most important astrophysical object in the universe. For astrophysicists, the atmosphere of the Sun presents an intriguing, complex and extremely varied environment generated by continuous dynamic, small-scale interactions between plasma and intricately structured magnetic fields.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2016-10-01"], "Project_ID": ["695075"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 239 860,80"], "Project_Title": ["REciprocal LOcal ADapatation: the genetic, behavioural and chemical study of the evolutionary maintenance of a mutualism"], "Total_Cost": ["EUR 239 860,80"], "Country": ["Germany"], "Project_ACR": ["RELOAD"], "Technology_Description": "The goal of this research is to identify and characterize genetic, behavioural and biochemical mechanisms underlying reciprocal local adaptation between partners in a complex mutualism. It will focus on a unique and outstanding model system found in the New World tropics: the \u201cdevil\u2019s gardens\u201d created by the ant, Myrmelachista schumanni, whose workers systematically attack and kill seedlings of foreign plants that germinate too close to their host plants. This cultivation behaviour results in low diversity, orchard-like stands of their host plants in the middle of some of the most diverse rainforests on earth. This project will bring together researchers from Harvard University and the Max Planck Institute to address three main questions through a combination of newly developed genome sequencing techniques, large-scale field-ecology behavioural experiments and state-of-the-art chemical analyses: (1) Do Myrmelachista schumanni and its host plants reciprocally influence each other\u2019s population sizes, level of gene flow and genetic structure? (2) How specialized are interactions between Myrmelachista schumanni and the several species of plants that it cultivates? (3) What are some of the proximate mechanisms underlying host specificity, and in particular, can ants recognize different plant species and if so, how? In carrying out this research, postdoctoral fellow Pierre-Jean Mal\u00e9 will expand his expertise by gaining training in phylogenomics and chemical ecology. The project, referred to here as \"RELOAD\" (forREciprocal LOcal ADaptations), will also enable him to broaden the ecological and evolutionary scale of his research, and enhance his long-term goal of obtaining a faculty position at a European university and/or research institution.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2016-07-01"], "Project_ID": ["705846"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["The impact of TFIID on the transcription initiation machinery \u2013 a structural perspective."], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["POL2-TFIID"], "Technology_Description": "Transcription is a first step of gene expression, a process by which a functional gene product is synthesized based on genetic information from DNA. Gene expression is tightly regulated with complex mechanisms that give cells the flexibility to adapt to a variable environment. Defects in regulation and transcription mechanisms leads to serious pathologies in cells and organisms, that in humans includes cancer development, autoimmunity and neurological disorders, cardiovascular diseases etc. ", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2016-03-01"], "Project_ID": ["708500"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITAT ZURICH", "UNIVERSITAT ZURICH", "INILABS GMBH"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Embedded Neuromorphic Sensory Processor"], "Total_Cost": ["EUR 150 000"], "Country": ["Switzerland", "Switzerland", "Switzerland"], "Project_ACR": ["NeuroPsense"], "Technology_Description": "Neuromorphic computing has demonstrated high potential for creating computing systems with order-of-magnitude improvements in energy efficiency and robustness to noisy or unreliable sensory signals, such as those inherent in vision. However, a significant roadblock to realizing the full potential of this emerging brain-inspired technology is the current practical need to use inefficient and slow (high latency) legacy von Neumann architectures to convert the input data that needs to be processed, and supply it to the neuromorphic system for further processing. ", "To": ["2017-11-30, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2015 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-06-01"], "Project_ID": ["713736"], "Call_for_Proposal": ["ERC-2015-PoC"]}, -{"Partners": ["UNIVERSITAT ZURICH"], "EU_Contribution": ["EUR 175 419,60"], "Project_Title": ["Systematic profiling of molecular changes during prion disease progression"], "Total_Cost": ["EUR 175 419,60"], "Country": ["Switzerland"], "Project_ACR": ["Prionomics"], "Technology_Description": "Prion diseases are fatal neurodegenerative diseases and are caused by proteinaceous infectious particles termed prions. The infectious agent of prion diseases has been identified decades ago, but the actual cellular processes that subsequently cause neurons to degenerate remain poorly understood. ", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["706138"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITAT ZURICH"], "EU_Contribution": ["EUR 175 419,60"], "Project_Title": ["A novel approach for detecting polygenic adaptation applied to FORest tree candidate GEne NETworks"], "Total_Cost": ["EUR 175 419,60"], "Country": ["Switzerland"], "Project_ACR": ["FORGENET"], "Technology_Description": "Unravelling the mechanisms of selection that allow species to adapt to changing environments has been a perpetual goal of evolutionary genetics. A current paradigm shift seems to radically change our view regarding the major mechanisms of evolutionary change. Ample experimental data indicates that most traits that potentially play a role in adaptations are controlled by many genes that may not act independently, but as members of complex gene interaction networks. Thus, it is widely agreed that most adaptation events in natural populations are reached via so-called polygenic adaptation, involving small changes at multiple genes at a time. Nevertheless, methods are still lacking to detect such adaptive gene associations. The main objective of FORGENET is to propose NetAdapt, a network-based test of polygenic selection for candidate-gene data. NetAdapt exploits candidate-gene data both as genotype and functional genomic data. First, based on the functional genomic information inherent to candidate gene data, it proposes to construct a gene interaction network, whose topology can be used to define a null hypothesis of neutrality. Second, based on the genotype data, it proposes a test for detecting selection on gene interactions, i.e. epistatic selection, based on linkage disequilibrium statistics. NetAdapt is expected to enhance our understanding how selection acts on gene networks and to propose new candidate genes for future genotyping. NetAdapt will be applied to published data on coniferous forest trees that have been genotyped from haploid tissue, which offers a straightforward application. Many conifers are endangered by climate change and estimating their adaptability is an important European research priority. FORGENET will study the evolution of flowering time genes at spruces along latitudinal gradients, and drought tolerance in Mediterranean pine species.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["705972"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Flame retardant Nanocontainers"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["NOFLAME"], "Technology_Description": "Since we live in the polymer age, and polymers are highly inflammable, flame retardants have become a key component in industry to reduce the impact of fires. Flame retardants save people's lives, their property and in some cases even the environment. However, traditional flame retardants like halogenated compounds present some serious disadvantages, like environmental persistence and toxicity, and their use is currently limited by REACH (EC 1907/2006). Halogen-free flame retardants like organophosphorus compounds or metal hydroxides, on the other hand, deteriorate the mechanical properties and have poor effectiveness. In this area, nanotechnology provides us some badly needed new approaches. In NOFLAME, we will explore a new approach based on the development of polymer flame retardant nanocontainers with high thermal stability, low flammability and good compatibility with polymeric matrices. These nanocontainers will help solve the problems of poor dispersion and low interfacial adhesion of the inorganic and hybrid nanomaterials applied so far. Furthermore, the ability to encapsulate a wide range of substances makes them highly attractive to develop multifunctional nanomaterials. The main activities within NOFLAME are: 1) the synthesis of several nanocontainers and the encapsulation of organic and inorganic flame retardant compounds, 2) the introduction of the nanocontainers in the polymer matrix and 3) the evaluation of their influence on the mechanical and flame retardant properties of the final material. Combining their expertise for NOFLAME, the fellow Dr. Maria Velencoso, the host MPIP and the partner BAM will execute a thrilling research project to produce novel flame retardant nanomaterials and meet an urgent need of the European plastics industry.", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2016-03-01"], "Project_ID": ["705054"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Synthetic Mimicry of Cellular Polarisation"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["POLAR"], "Technology_Description": "Biological self-organisation through spontaneous symmetry breaking is essential for the emergence and maintenance of life. Cell polarity, where an asymmetric distribution of molecules is achieved within a cellular compartment, is one of the simplest and most studied examples. However, due to the diversity and complexity of nature, and despite the many known pathways and theoretical models, the fundamental mechanisms are still poorly understood. I propose a \u2018bottom-up\u2019 synthetic biology approach to build a synthetic system capable of mimicking cellular polarisation in an artificial compartment. Modular fusion proteins will be engineered from small, well-characterised protein domains and reconstituted into artificial membrane-bound compartments such as Giant Unilamellar Vesicles (GUVs) and microfluidic water-in-oil droplets. The self-organisation of these proteins through autocatalytic membrane-recruitment will be monitored with a variety of fluorescence microscopy techniques. In doing so, I will create a minimal, defined system in which to test general principles of biological self-organisation, abstracted from the \u2018noise\u2019 of natural systems. Further, orthogonal synthetic systems could be introduced into living organisms to control morphology and other functions, or be used to build higher-level mimics of life such as proto-cells.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-09-01"], "Project_ID": ["705587"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITAT ZURICH"], "EU_Contribution": ["EUR 175 419,60"], "Project_Title": ["Beyond double-strand break repair: specific mechanisms of homologous recombination at stressed replication forks."], "Total_Cost": ["EUR 175 419,60"], "Country": ["Switzerland"], "Project_ACR": ["RecInRep"], "Technology_Description": "Genomic instability is the main driving force of tumourigenesis, as highlighted by the cancer predisposition conferred by mutations in caretaker genes. DNA replication stress has recently received much attention, for its causative role in transformation and as a strategy for cancer therapy. Besides other mechanisms protecting replicating chromosomes from genotoxic stress, transient fork remodelling into four-way junctions (fork reversal) is emerging as a key transaction to assist template repair or to tolerate DNA damage and replication interference. Factors and mechanisms modulating this transaction are just beginning to emerge. The central recombinase RAD51 was recently shown to promote fork reversal, uncovering a fork-specific role for homologous recombination (HR) proteins, beyond their established role in the double-strand break repair. However, the molecular determinants controlling RAD51-mediated fork remodelling are yet unknown. I propose to gain mechanistic insight into the role of RAD51 and other HR proteins in replication stress, using an integrated, multidisciplinary approach, which combines my current biochemical expertise with specialized cell biology and single-molecule techniques available in the host lab. In particular, I will first set up a microscopy-based screen to identify factors that regulate RAD51 recruitment at replication forks upon stress. Then, I will use a combination of single-molecule and cell biology techniques to investigate how these novel RAD51 regulators mediate in vivo RAD51 role in fork protection and remodelling. Finally, I will establish an in vitro system to study biochemically the mechanisms by which RAD51 and the novel identified factors catalyse replication fork remodelling. I believe that this \"holistic\" approach will be instrumental not only to define the molecular basis of cancers with a HR-defective genetic background, but also to provide the groundwork to develop more effective chemotherapeutic strategies.", "To": ["2018-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-04-01"], "Project_ID": ["704817"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 181 002,60"], "Project_Title": ["Discrete Dirac Mechanics and Geometric Numerical Integration Methods for Plasma Physics"], "Total_Cost": ["EUR 181 002,60"], "Country": ["Germany"], "Project_ACR": ["DDM-GNI"], "Technology_Description": "In recent years it has been realised that the preservation of certain structures and properties of mathematical equations is of utmost importance when bringing them in a form understandable by computers. Ignoring such properties often leads to incorrect results in the corresponding simulations. In plasma and fusion physics this is especially true as the mathematical equations are highly complex and direct comparison with the experiments is very difficult. Still, the application of structure-preserving numerical algorithms to plasma physics has not gained much attention and todays computer codes do not use such methods. Consequently, these codes are not able to reproduce important physical effects observed in the experiments, hindering progress in research.", "To": ["2018-03-31, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2016-04-01"], "Project_ID": ["708124"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["A Computational Framework For Quantitative Modeling of Leaf Development in Arabidopsis and Cardamine"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["CFQMLD"], "Technology_Description": "Understanding how form emerges in living organisms is a fundamental challenge for biology. Progress, however, has been confounded by the complex chain of interactions underlying the organization of macroscopic forms from molecular processes. Consequently, insights into the manner in which individual genes contribute to the development of form have been elusive; even in well-studied model organisms. In this context, leaves provide a striking example of the self-organization of form \u2013 displaying remarkable diversity within and between species. Now, exploiting the close relation between simple leafed A. thaliana and compound leafed C. hirsuta, the Tsiantis lab has identified the key genetic factors underlying their distinct leaf shapes. This opens the door to a detailed understanding of the developmental factors sculpting leaf form. ", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-01-01"], "Project_ID": ["703886"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Chromatin targeting and remodelling by bacterial effectors in plant immunity"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["CHERI"], "Technology_Description": "In nature, plants are challenged by disease-causing pathogens such as viruses, bacteria and fungi. Understanding mechanisms of plant disease and disease resistance is of fundamental importance to sustainable agriculture and human health. Unlike mammals, plants lack a circulating immune system. Plants instead rely on the innate immune capacity of each cell and systemic signals that disseminate from infection sites. Successful pathogens use effectors to suppress plant immunity and cause disease. Plants have evolved disease resistance genes encoding immune receptors that perceive specific pathogen effectors to mount effector-triggered immunity. In Arabidopsis, a heteromeric pair of intracellular immune receptors forms a functional recognition complex which senses virulence activities of two structurally unrelated bacterial effectors at the nuclear chromatin. Results suggest that effector targeting of histone modifications and chromatin remodelling interferes with host basal immunity and that this is transduced by the receptor pair to activation of defence pathways. The underlying molecular mechanisms remain unclear. We have found that the two bacterial effectors interact with an overlapping set of chromatin-associated proteins and with certain immune receptor domains. We hypothesize that the effectors converge on the same chromatin machinery for promoting disease and that their actions are intercepted by the immune receptor system which is physically connected to basal immunity signalling components. By using the effectors as molecular probes, this proposal aims to elucidate how the chromatin environment is modulated during infection and how effector perturbations are converted to effective immunity.", "To": ["2018-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2016-04-01"], "Project_ID": ["705631"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Elucidating the Mechanisms of Insect\u2019s Chemical Taste to Understand Specific Host-Plant Selection"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["ChemoSense"], "Technology_Description": "The sense of taste enables an animal to decide what it eats and drinks. Insects are able to discriminate among soluble chemicals via their gustatory receptors (GRs) in order to accept or reject a certain food plant or initiate mating and oviposition. Despite their essential role in the insect\u2019s overall food intake, survival and reproductive success, relatively little is known about insect GRs, especially in beetles. This is surprising given their importance as agricultural and forestry pests, their global distribution and huge species number as herbivorous insects. I aim to identify and characterise GRs that mediate host plant selection in a specialist poplar leaf beetle, Chrysomela populi. These beetles feed on economically important poplar trees and damage timber plantations worldwide. It is hypothesised that the phenolic glucoside salicin in poplar is a major taste stimulant for C. populi and enhances feeding activity. However, it is unknown how salicin or, alternatively, other taste stimulants are detected by, and interact with specific GRs in C. populi to elicit feeding behaviour. I will elucidate these mechanisms by (i) identification of candidate genes encoding GRs in C. populi via tissue specific transcriptome sequencing and transcript visualisation via RNA-FISH, (ii) knock-down of single GR genes via RNAi to test the feeding behaviour of RNAi-silenced beetles, and (iii) test whether any of the taste stimulants from poplar function as in vivo and in vitro ligand for specific C. populi GRs by tissue-specific electrophysiological recordings and heterologous expression, respectively. These results will shed new light on the question how GRs function as regulators for herbivorous beetles to select and consume specific plants, which will significantly advance our knowledge in understanding host plant selection. As poplar leaf beetles are important pests, the results may also pave the way for timely development of sustainable pest management in forestry.", "To": ["2018-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2016-12-01"], "Project_ID": ["705151"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITAT ZURICH"], "EU_Contribution": ["EUR 175 419,60"], "Project_Title": ["Understanding and Boosting Motivation using Brain Stimulation"], "Total_Cost": ["EUR 175 419,60"], "Country": ["Switzerland"], "Project_ACR": ["BOOMSTIM"], "Technology_Description": "Imagine losing the motivation to do the job that you used to enjoy. The idea of doing those tasks overwhelms you. You cannot push yourself to give the best efforts and end up doing the bare minimum. What are the brain processes that cause such depleted motivation and how can we restore the motivation to put in effort in order to achieve goals? To address these questions, I propose a series of studies to gain a theoretical and practical understanding of the causal relationship between brain computations of effort and the motivation to energise behavior to achieve goals. Specifically I plan to conduct, for the first time, a combined brain stimulation-functional neuroimaging (Transcranial Magnetic Stimulation-TMS; functional Magnetic Resonance Imaging-fMRI) experiment to perturb brain regions whose activity represents the amount of effort costs, and measure its impact on neural value computations in a remote but interconnected brain region known to drive choice behavior. This change in causal interplay in the brain should have a quantifiable impact on the motivation to expend effort. I will then use this theoretical knowledge to design a large-scale application of an inexpensive brain stimulation method (Transcranial Direct Current Stimulation-tDCS) to increase motivation, thus establishing a realistic and versatile protocol for restoring motivation in rehabilitative settings. In sum, my research will address the overarching question of how motivation can be enhanced with neuroscience techniques, by combining computational and neuroimaging advances in effort discounting with causal brain stimulation methods. This project will allow me to be trained in the two most common brain stimulation techniques at a pioneering lab in Europe, and forge a new collaborative research line at the Laboratory for Social and Neural Systems Research at the University of Zurich.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["702799"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Reconstitution of the basic molecular mechanism of phagocytosis \u2013 a bottom-up synthetic biology approach"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["minimal-phagocyte"], "Technology_Description": "The ability of cells to engulf large objects, such as invading microorganisms or apoptotic cells, is crucial to innate immunity and tissue remodelling. The molecular basis of this process - phagocytosis - is complex, involving numerous receptors and signalling pathways. Nevertheless, the biophysical process is always the same: the cell membrane deforms and reshapes to wrap around the particle, and upon closure and abscission of the resultant cup, the particle is internalised. Although the key molecular players in individual phagocytic pathways have been identified, we still know very little about the basic biophysics common to all phagocytic pathways. I propose to fill this gap in our knowledge by creating a \u201cminimal phagocyte\u201d: I aim to reconstitute a minimal, dynamic actin cytoskeleton and artificial phagocytic receptors in giant unilamellar vesicles (GUVs), thereby identifying the molecular components that are not only necessary but also sufficient for phagocytosis. Using synthetic biology to build a bottom-up model of phagocytosis should answer many open questions, including: are spatial cues resulting from particle binding required for membrane wrapping around the particle? Is directed initiation of actin polymerisation sufficient to render GUVs capable of phagocytosis? What is the role of the membrane-supporting actin cortex and how does the affinity of the receptors affect the engulfment process? Beyond phagocytosis, the minimal-model approach I propose will also be useful to study other cellular functions requiring actin-driven membrane reorganisation, such as cell mobility. In line with the objectives set by ERA-NET ERASynBio and the Horizon 2020 work programme (which identified synthetic biology as one of the \u201ccutting-edge biotechnologies as future innovation drivers\u201d), the creation of \u201cprotocells\u201d will not only enhance our understanding of biology, but ultimately also result in novel biotechnological applications, such as improved drug delivery systems.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2016-09-01"], "Project_ID": ["703132"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 984 375"], "Project_Title": ["Ultrafast spin transport and magnetic order controlled by terahertz electromagnetic pulses"], "Total_Cost": ["EUR 1 984 375"], "Country": ["Germany", "Germany"], "Project_ACR": ["TERAMAG"], "Technology_Description": "In order to fully exploit the electron spin as a signal carrier in future information processing, spins need to be transported and flipped as fast as possible. Spintronics research aims at implementing these operations by electric fields in circuitry, but has so far been limited to frequencies below ~10 GHz. The much faster complementary femtomagnetism approach employs femtosecond laser pulses (carrier frequency ~400 THz), but is not compatible with microelectronics technology.", "To": ["2021-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2016-07-01"], "Project_ID": ["681917"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 884 875"], "Project_Title": ["The Physics of Galaxies 7 Gyr Ago"], "Total_Cost": ["EUR 1 884 875"], "Country": ["Germany", "Germany"], "Project_ACR": ["LEGA-C"], "Technology_Description": "Over the past decade, redshift surveys and multi-wavelength imaging campaigns have drawn up an empirical picture of how many stars had formed in which types of galaxies over the history of the universe. However, we have yet to unravel the individual pathways along which galaxies evolve, and the physical processes that drive them. Continuing with the previous approach -- larger and deeper photometric samples -- is not adequate to achieve this goal. A change of focus is required.", "To": ["2021-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2016-04-01"], "Project_ID": ["683184"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Defining the genetics of grapheme-colour synaesthesia"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["SynGenes"], "Technology_Description": "Synaesthesia is a common neurodevelopmental phenomenon (2-5% of the population) where stimulation of one sense automatically triggers an experience of another. Familial clustering indicates that synaesthesia is highly heritable. However, this genetic contribution is poorly understood and likely heterogeneous, a major hindrance to our understanding of the neurobiology. My objective is to remove this barrier through the most comprehensive interrogation of synaesthesia genetics to date, utilizing state-of-the-art technologies and integrative approaches.", "To": ["2018-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2016-06-01"], "Project_ID": ["704393"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["STICHTING WAGENINGEN RESEARCH"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["Development of an in vitro cellular model to predict the immunological impact of dietary proteins"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["IVSysImmunoProt"], "Technology_Description": "As the world population continues to grow and a shortage of protein supply is foreseen, there is a need to identify new and sustainable protein sources. While these alternative proteins must be of high nutritional quality, they also need to be safe for consumption. Dietary proteins and their digestion products can influence a number of regulatory systems, including the immune system. By interacting with elements of the immune system, proteins can help balance and stabilize immune responses, but may also trigger adverse effects such as allergic reactions. While the effects of proteins and peptides on the adaptive immunity have been examined in a number of studies, few have studied how these molecules are absorbed through the small intestine and interact with the innate immune system. Since, in order to trigger an immune response proteins must first be transported across the intestinal wall and interact with the innate immune system, understanding these processes is key to determining the immunological effects of protein consumption. The aim of the proposed project is to develop an in vitro model to evaluate the impact of dietary proteins on the immune system. This research will first examine the uptake of proteins and their digests across the intestinal wall using cellular models mimicking the intestinal epithelium and subsequently investigate the effect of the absorbed proteins/peptides on the immune system\u2019s key players, including the dendritic and T cells. The model system that this research aims to develop could help shed light on the roles played by dietary proteins in regulating intestinal immunity and serve as a tool to evaluate the immunological properties of novel and sustainable proteins. Thus, this research is of relevance not only to the European food industry, but also to public health.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Research Organisations"], "From": ["2016-09-01"], "Project_ID": ["703929"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Spectral synthesis of multidimensional supernova explosion models"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["SNSM"], "Technology_Description": "Core-collapse supernovae are the explosive deaths of massive stars. They are the main production sites of the heavy elements in the Universe, drive galactic dynamic and chemical evolution, and produce exotic remnants such as black holes and neutron stars. To interpret observations and advance our understanding of the origin of the elements, sophisticated spectral models are needed. The main science objective in this proposal is to compute the first spectral models of multi-dimensional core collapse explosion simulations. These models will then be compared with available high-quality data to derive information on nucleosynthesis yields and supernova structure. The proposed work involves the development of spectral modelling tools from current 1D to multi-D capability, and application of these to recently computed state-of-the-art 3D explosion simulations. This innovative project will allow a milestone in supernova research to be reached by producing the first light curves and spectra of modern 3D simulations, and will approach us to solving an almost 50 year standing mystery of how supernovae explode and how the elements are produced.", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2016-10-01"], "Project_ID": ["702538"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Elucidation of autophagy using novel chemical probes"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["ChemBioAP"], "Technology_Description": "The interest on autophagy, an evolutionarily conserved process in eukaryotes, has enormously increased in the last years, since autophagy is involved in many diseases such as cancer and neurodegenerative disorders. Autophagosome formation is the key process in autophagy. Despite extensive work, the model of autophagosome formation is not yet well established. Some important questions on autophagosome biogenesis remain to be elusive, such as where the bona fide marker protein of autophagosome, LC3, is lipidated, how lipidated LC3 functions in autophagosome formation, and how the proteins for LC3 lipidation and delipidation are involved in autophagosome formation. Although genetic approaches have been useful to identify genes involved in autophagy, they are chronic and thereby the dynamics of phenotypic change cannot be followed, making them not suited for study highly dynamic process such as autophagosome formation. Herein, I propose to develop and use novel chemical probes to address these issues. First, I plan to prepare semi-synthetic caged LC3 proteins and apply them to monitor dynamics of autophagosome formation in the cell in order to address those questions on autophagosome formation. The semi-synthetic LC3 proteins are expected to confer a temporal control and to realize manipulation of protein structure, which renders such studies possible. Second, I intend to develop a versatile approach targeting specific endogenous proteins using a reversible chemically induced dimerization (CID) system, termed as \u201cknock on and off\u201d strategy. I plan to use this approach to elucidate the function of two distinct PI3K complexes in autophagosome formation. On one hand, the establishment of novel approaches will open up a new avenue for studying biological processes. On the other hand, the use of the tool will reveal the mechanism of autophagy.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2016-09-01"], "Project_ID": ["678899"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 495 000"], "Project_Title": ["Are social skills determined by early live experiences?"], "Total_Cost": ["EUR 1 495 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["ApeAttachment"], "Technology_Description": "Social bonding success in life impacts on health, survival and fitness. It is proposed that early and later social experience as well as heritable factors determine social bonding abilities in adulthood, although the relative influence of each is unclear. In humans, the resulting uncertainty likely impedes psychological and psychiatric assessment and therapy. One problem hampering progress for human studies is that social bonding success is hard to objectively quantify, particularly in adults. I propose to directly address this problem by determining the key influences on social bonding abilities in chimpanzees, our closest living relative, where social bonding success can be objectively quantified, and is defined as number of affiliative relationships maintained over time with high rates of affiliation.", "To": ["2021-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2016-04-01"], "Project_ID": ["679787"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["UNIVERSITAT ZURICH", "UNIVERSITAT ZURICH"], "EU_Contribution": ["EUR 1 489 340,95"], "Project_Title": ["The Role of Local Protein Degradation in Neurotransmitter Release and Homeostatic Plasticity"], "Total_Cost": ["EUR 1 489 340,95"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["SynDegrade"], "Technology_Description": "While many neurons live for decades, the proteins that determine neural function have half-lives of hours to weeks. On the one hand, this allows for plastic changes during development and learning. On the other hand, this poses the question of how stable neural function can be achieved and maintained at all. Several neurological diseases, such as epilepsy or migraine, have been linked to uncontrolled neural function. However, the molecular mechanisms that stabilize nervous system function are poorly understood. The major site of regulation of neural activity is the chemical synapse. Synaptic function is tightly linked to the specific composition and abundance of proteins at synapses. However, the molecular pathways underlying the homeostatic control of protein levels at synapses, henceforth called synaptic proteostasis, are largely unknown.", "To": ["2021-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["679881"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Towards a Complete Quantitative Model of the FOF1 ATP Synthase"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["F-ATPase"], "Technology_Description": "The FOF1-ATPase is a complex nanomotor that synthesizes nearly 90% of the ATP made during cellular respiration. It consists of two coupled rotary motors: an integral membrane complex driven by proton flow across lipid bilayers (FO) and an enzymatic complex that converts ADP and inorganic phosphate to ATP (F1). The rotational portion of these motors acts as a camshaft, inducing conformational changes that lead to ATP synthesis in the F1 motor\u2019s three functional catalytic sites. The F1 motor can perform ATP synthesis in the absence of FO, and it can also work in reverse, hydrolyzing ATP to pump protons against an established gradient. Over the last 30 years many important aspects of this motor\u2019s function have been elucidated by careful biochemical work and further understood by clever biophysical experiments. However, there is still not a complete, quantitative description of the whole thermodynamic cycle\u2014one that fully describes the interactions between all three separate catalytic sites and accounts for the need to exchange ATP (found abundantly) for the relatively sparse ADP.", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2016-03-01"], "Project_ID": ["707154"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Mechanisms of protein translocation in ER-associated protein degradation and the related protein import into the apicoplast of Plasmodium falciparum"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["ERAD_SELMA"], "Technology_Description": "The removal of misfolded proteins is an essential process in all cells. Failure to dispose of such proteins often results in disease. A particularly intriguing process serves to discard misfolded proteins from the endoplasmic reticulum (ER). The ER does not itself degrade proteins, so machinery has evolved that moves misfolded proteins into the cytosol where they can be degraded by the proteasome. This retro-translocation process is called ERAD (for ER-associated protein degradation). By comparison with other membrane translocation processes, the mechanism of ERAD is poorly understood. How are misfolded proteins distinguished from folding intermediates? How are proteins moved across the membrane? How is the energy for membrane translocation provided? To answer these fundamental questions I will use a combination of in vitro reconstitution experiments with purified proteins from S. cerevisiae and experiments in intact yeast cells. It appears that some ERAD components have been adapted to function in protein translocation in a very different setting. Many parasites like the malaria causing P. falciparum contain a plastid-like organelle, called the apicoplast. It is the site of several metabolic pathways essential for the parasite\u2019s survival, and thus an important drug target. Like other organelles of endosymbiotic origin, the apicoplast lost most of its genetic information and has to import proteins. This is a particularly challenging endeavour because four membranes surround the apicoplast. It is thought that symbiont specific ERAD-like machinery (SELMA) mediates proteins translocation across the second-outermost membrane. However, not much is known about SELMA. What is its molecular composition? Which aspects of SELMA are conserved in comparison to the classical ERAD machinery? I will address these important questions using a completely novel combination of biochemical and genetic approaches.", "To": ["2021-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2016-03-01"], "Project_ID": ["677770"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 497 374,99"], "Project_Title": ["Rydberg dressed quantum many-body systems"], "Total_Cost": ["EUR 1 497 374,99"], "Country": ["Germany", "Germany"], "Project_ACR": ["RyD-QMB"], "Technology_Description": "The project \u201cRydberg dressed quantum many-body systems\u201d (RyD-QMB) will experimentally study long-range interacting atomic quantum many-body systems with tailored microscopic interactions. It will explore supersolidity expected for ultracold bosonic systems with soft-core interactions and realize quantum magnets, that are designable almost at will and feature unprecedented coupling strengths. As such, it opens new directions for atomic quantum simulation and paves the way towards the experimental study and the design of frustrated magnets, interacting topological systems and artificial quantum gauge fields, topics, that not only push the limits of quantum simulators for solid state physics, but also reach out into the field of high energy physics.", "To": ["2021-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2016-06-01"], "Project_ID": ["678580"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 2 500 000"], "Project_Title": ["Myelinic nanochannels in neurodegenerative diseases"], "Total_Cost": ["EUR 2 500 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["MyeliNANO"], "Technology_Description": "Myelin is made by highly specialized glial cells and enables fast axonal impulse propagation. We have discovered that oligodendrocytes in the CNS are, in addition to myelination, required for the integrity and survival of axons, independent of the presence or absence of myelin itself. More recently, we found the underlying mechanism and could show that glycolytic oligodendrocytes provide axons with pyruvate/lactate. These metabolites are transported through a system of myelinic nanochannels to the axonal compartment, in which mitochondria generate ATP. The finding was a paradigm-shift for the physiological function of axonassociated glia, and opens now the intriguing possibility that oligodendrocytes are important modifiers of neurological diseases in which myelinated axons are lost. This includes, in addition to multiple sclerosis, also classical neuropsychiatric disorders. We will generate novel genetic tools in mice that allow us to study the role myelin and secondary axonal loss in higher brain functions. We will test the challenging hypothesis that reducing oligodendroglial support of axonal metabolism is a risk for differen neurodegenerative disorders. These involve the previously neglected ultrastructure of CNS myelin with cytosolic (20-300 nanometer wide) channels within the myelin sheath. These 'nanochannels' couple the oligodendrocyte soma metabolically to the adaxonal space, but are vulnerable to aging and physical injury. We hypothesize that cellular mechanisms as diverse as neuroinflammation and the aggregation of misfolded proteins in myelinic nanochannels cause perturbations of the axonal energy metabolism. When combined, the findings of MyeliNANO will shed new light on previously unknown functions of CNS myelin and will pave the way for metabolic neuroprotection as a therapeutic approach to a range of neurodegenerative diseases.", "To": ["2021-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2016-04-01"], "Project_ID": ["671048"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["UNIVERSITAT ZURICH", "UNIVERSITAT ZURICH"], "EU_Contribution": ["EUR 1 991 721"], "Project_Title": ["General Relativistic Effect in Galaxy Clustering as a Novel Probe of Inflationary Cosmology"], "Total_Cost": ["EUR 1 991 721"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["GREinGC"], "Technology_Description": "Substantial advances in cosmology over the past decades have firmly established the standard model of cosmology. However, the physical nature of the early Universe and dark energy (or inflationary cosmology) remains poorly understood. To resolve these issues, a large number of galaxy surveys are planned to measure millions of galaxies in the sky, promising precision measurements of galaxy clustering with enormous statistical power. Despite these advances in observation, the standard theoretical description of galaxy clustering is based on the Newtonian description, inadequate for measuring the relativistic effects from the early Universe and the deviations of modified gravity from general relativity. In recent years, the applicant, for the first time, developed the linear-order general relativistic description of galaxy clustering and showed that the relativistic effect in galaxy clustering is already measurable at a few-sigma level in current surveys like the Sloan survey", "To": ["2021-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["680886"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 999 625"], "Project_Title": ["The tiny and the fast: the role of subcortical sensory structures in human communication"], "Total_Cost": ["EUR 1 999 625"], "Country": ["Germany", "Germany"], "Project_ACR": ["SENSOCOM"], "Technology_Description": "In Europe, approximately one hundred million people are impaired in their communication abilities. These include people with autism spectrum disorders (ca. 3 million) and individuals with dyslexia (ca. 50 million). Current neuroscience research typically associates cognitive functions including communication abilities with the cerebral cortex. By and large, this approach ignores the complex subcortical processing machinery before sensory signals reach the cortex. However, recent pioneering studies imply that dysfunction in tiny subcortical sensory structures can cause selective deficits in our ability to understand others. My goal is to (i) investigate the role of subcortical sensory structures in analysing communication signals and (ii) specify how dysfunction in subcortical-cortical interaction can cause human communication disorders. To do this we will combine very recently developed ultra-high-resolution neuroimaging with a cutting-edge multimodal approach including neurostimulation, and computational neuroimaging. The project will relate sensory subcortical responses to concrete communication behaviour, as observed in healthy individuals and individuals with communication disorders. I expect two key results: First, we will uncover the principles of how subcortical sensory structures operate for dynamic auditory and visual communication signals; this will lead to a novel model of subcortical-cortical interactions that can explain key functions in human communication. Second, the results will resolve long-standing puzzles about the nature of two of the most common hereditary communication deficits (developmental dyslexia and autism spectrum disorders). Immediate consequences of this proposal will include a translational project aimed at improving communication functions with behavioural interventions. Together, the findings may revolutionise our understanding of how sensory subcortical structures shape one of our most important cognitive functions\u2014communication.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2016-01-01"], "Project_ID": ["647051"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 2 750 000"], "Project_Title": ["Spin Orbitronics for Electronic Technologies"], "Total_Cost": ["EUR 2 750 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["SORBET"], "Technology_Description": "Spintronics is a vibrant field of research that involves the intimate interaction of magnetic structure on the atomic scale with spin currents and spin-polarized charge currents. SORBET is focussed on an emerging sub-field of spintronics, namely that of spin orbitronics. Recent discoveries in this field concern the interplay of several distinct spin orbit coupling derived phenomena that, together, allow for the highly efficient current", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2015-11-01"], "Project_ID": ["670166"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["UNIVERSITAT ZURICH", "UNIVERSITAT ZURICH"], "EU_Contribution": ["EUR 2 500 000"], "Project_Title": ["Function and malfunction of the prion protein"], "Total_Cost": ["EUR 2 500 000"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["PRION2020"], "Technology_Description": "Transmissible spongiform encephalopathies (TSE) are caused by the ordered aggregation of PrPC into prions consisting of PrPSc. Similar pathogenetic principles operate in Alzheimer\u2019s and Parkin-son\u2019s disease, and a growing list of further diseases whose prevalence is steadily rising. Familial TSE are invariably associated with PrPC mutations, and the dearth of genetic modifiers has hampered our understanding of prion diseases. Therefore, the first objective of my proposal utilizes a cell-based high-throughput quantitative prion replication assay (developed during my previous ERC instalment) for genome-wide unbiased screens employing new genetics tools (CRISPR, siRNA li-braries, next-gen sequencing) to identify modifiers of prion uptake, replication, and secretion. The second objective aims at clarifying the basis of prion neurotoxicity and will be developed along two alleys: (a) we will uncover the molecular basis of spongiosis (the neuronal vacuolation characteristic of prion diseases), which we suspect to be a main driver of pathology, and (b) we will perform CRISPR-based synthetic lethality screens to identify genes that become essential to prion-infected cell lines (which do not experience prion toxicity) and may not be expressed by neurons. The third objective is to understand the function of PrPC in cellular physiology, and focuses on our evidence that (a) PrPC interacts with an orphan G-protein coupled receptor to maintain peripheral myelin integrity and (b) that PrPC may trigger cell death in response to ER stressors. While certain pathways of degeneration will undoubtedly be specific to prion infections, I expect that some targets will prove common to a variety of protein aggregation diseases including Alzheimer\u2019s and Parkinson\u2019s disease, and may perhaps translate into novel diagnostics and therapeutics. Hence the proposed project may not only open new perspectives in prion biology but also yield insights applicable to much more common diseases.", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-11-01"], "Project_ID": ["670958"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Comparative analysis of planarian regeneration - why some worms regenerate while others don\u2019t"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["RegEvolve"], "Technology_Description": "The ability to regenerate lost body parts is widespread amongst animals, yet humans, for example, can only regenerate specific organs. Why some animals regenerate while others hardly do remains a fascinating conundrum, especially so in face of \u201csurvival of the fittest\u201d. Even amongst planarian flatworms, famous for their ability to regenerate from random tissue fragments, species exist that have completely lost the ability to regenerate. This proposal will exploit the unique diversity of planarian regenerative abilities amongst to ask why some worms regenerate while others do not. We and others have established that planarian Wnt signalling acts as critical node in the evolution of regeneration defects. Using this finding as strategic focus for comparisons between regenerating and non-regenerating species, we will investigate i) the cell biological mechanisms that shape Wnt pathway activity; ii) the genomic mechanisms that differentially deploy critical pathway regulators; and iii) evolutionary mechanisms in form of life history trait trade-offs as possible driving force behind the drift of regenerative abilities. Key to the project is a diverse collection of regenerating and regeneration-deficient species that my lab has established. Focused comparisons between our two primary model species D. lacteum and S. mediterranea, employing pan-planarian antibodies and functional genomics, will allow us to understand the detailed causes of altered pathway activity. Comparisons amongst the entire collection of 50 species will provide the necessary breadth for identifying and studying the evolutionary principles that \u201cnaturally select\u201d regeneration-deficient planarians. The comparative approach of RegEvolve will thus uniquely bridge the proximate (molecular)- with the ultimate (evolutionary) causes of regeneration defects and such interdisciplinary endeavour between molecular and evolutionary regeneration research will lead to new and profound insights into both fields.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2015-10-01"], "Project_ID": ["649024"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["UNIVERSITAT ZURICH", "UNIVERSITAT ZURICH"], "EU_Contribution": ["EUR 2 498 915"], "Project_Title": ["Mesoscale Brain Dynamics: Computing with Neuronal Pathways"], "Total_Cost": ["EUR 2 498 915"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["BRAINCOMPATH"], "Technology_Description": "Brain computations rely on proper signal flow through the complex network of connected brain regions. Despite a wealth of anatomical and functional data \u2013 from microscopic to macroscopic scale \u2013 we still poorly understand the principles of how signal flow is routed through neuronal networks to generate appropriate behavior. Brain dynamics on the 'mesoscopic' scale, the intermediate level where local microcircuits communicate via axonal pathways, has remained a particular blind spot of research as it has been difficult to access under in vivo conditions. Here, I propose to tackle the mesoscopic level of brain dynamics both experimentally and theoretically, adopting a fresh perspective centered on neuronal pathway dynamics. Experimentally, we will utilize and further advance state-of-the-art genetic and optical techniques to create a toolbox for measuring and manipulating signal flow in pathway networks across a broad range of temporal scales. In particular, we will improve fiber-optic based methods for probing the activity of either individual or multiple neuronal pathways with high specificity. Using these tools we will set out to reveal mesoscopic brain dynamics across relevant cortical and subcortical regions in awake, behaving mice. Specifically, we will investigate sensorimotor learning for a reward-based texture discrimination task and rapid sensorimotor control during skilled locomotion. Moreover, by combining fiber-optic methods with two-photon microscopy and fMRI, respectively, we will start linking the meso-level to the micro- and macro-levels. Throughout the project, experiments will be complemented by computational approaches to analyse data, model pathway dynamics, and conceptualize a formal theory of mesoscopic dynamics. This project may transform the field by bridging the hierarchical brain levels and opening significant new avenues to assess physiological as well as pathological signal flow in the brain.", "To": ["2021-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-02-01"], "Project_ID": ["670757"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Density-Functional Theory for Thermoelectric Phenomena"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["ThermalDFT"], "Technology_Description": "The development of sustainable energy sources poses a great challenge for our society. Due to the scarcity of natural resources it is of crucial importance to optimize the efficiency of our energy production. Virtually every energy generation process is accompanied with the generation of waste heat, for example in the form of plumes from power plants. Even if only part of this waste heat is transformed into useful energy the overall efficiency of energy production is increased. In recent years there has been renewed interest in thermoelectric phenomena, due to their potential impact on designing new devices capable of converting waste heat into electricity. Furthermore, it has become evident that nanoscale devices, which implement their functionality at the level of single molecules, potentially offer a much enhanced efficiency for the conversion of heat to electricity compared to bulk materials.", "To": ["2018-10-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2016-10-15"], "Project_ID": ["701796"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 946 250"], "Project_Title": ["Logical Foundations for the Future of Safe Systems Programming"], "Total_Cost": ["EUR 1 946 250"], "Country": ["Germany", "Germany"], "Project_ACR": ["RustBelt"], "Technology_Description": "A longstanding question in the design of programming languages is how to balance safety and control. C-like languages give programmers low-level control over resource management at the expense of safety, whereas Java-like languages give programmers safe high-level abstractions at the expense of control.", "To": ["2021-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2016-04-01"], "Project_ID": ["683289"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["UNIVERSITAT ZURICH", "UNIVERSITAT ZURICH"], "EU_Contribution": ["EUR 2 913 143,75"], "Project_Title": ["Film Colors. An Interdisciplinary Approach."], "Total_Cost": ["EUR 2 913 143,75"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["Filmcolors"], "Technology_Description": "Film is in essence colored light projected onto a screen. Its aesthetics are thus highly determined by the material properties of film and the optical configuration of the cinematic apparatus. To this day, however, there is no systematic study of the relationship between the technology and aesthetics of film colors, despite the fact that, following the digital turn in film production and distribution, the understanding of this relationship is more essential than ever before.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["670446"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["UNIVERSITAT ZURICH", "UNIVERSITAT ZURICH"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Mechanisms and functional significance of diffusion barriers for asymmetric segregation of age in neural stem cells"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["STEMBAR"], "Technology_Description": "Neural stem/progenitor cells (NSPCs) continue to generate new neurons throughout life in distinct regions of the mammalian brain. Adult neurogenesis has been implicated in brain function and altered neurogenesis has been associated with a number of neuropsychiatric diseases such as depression and cognitive ageing. A key feature of somatic stem cell division is the ability to divide asymmetrically and symmetrically for neurogenic and self-renewing cell division, respectively. However, it remains unknown how age is segregated in the context of somatic stem cell division, i.e., if the cellular history and the replicative age of the mother stem cell is passed onto its progeny. Thus, we hypothesized that \u2013 similar to the previously described barrier that exists in budding yeast \u2013 somatic stem cells, and more specifically NSPCs, form a diffusion barrier during cell division to retain aging or senescence factors within the stem cell, generating a mechanism for how age is asymmetrically distributed. Indeed, we found the existence of a diffusion barrier that is established during NSPC division, identifying a new mechanism of cellular segregation and asymmetry. With the program proposed here I aim i) to study the effects of the barrier on asymmetric segregation of aging factors and to develop novel tools to visualize the mammalian diffusion barrier, ii) to characterize the presence of a diffusion barrier in endogenous NSPCs in relation to cell division history, iii) to analyse the mechanisms underlying age-associated weakening of the NSPC diffusion barrier, and iv) to evaluate if genetic and pharmacological rescue of the barrier is sufficient to ameliorate the age-dependent decline of neurogenesis. The insights gained from the studies proposed here have the potential to substantially advance our understanding of NSPC biology, to identify a new mechanism underlying the neurogenic process, and to reshape our understanding of asymmetric cell division of somatic stem cells.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["682256"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 2 495 593,75"], "Project_Title": ["Presynaptic Regulatory Principles in Synaptic Plasticity, Neuronal Network Function, and Behaviour"], "Total_Cost": ["EUR 2 495 593,75"], "Country": ["Germany", "Germany"], "Project_ACR": ["SYNPRIME"], "Technology_Description": "Neuronal signalling via synaptic vesicle (SV) fusion is the fastest membrane fusion event in mammalian cells. Its speed and the ability of presynapses to sustain SV fusion at high stimulation rates are key requirements for brain function. Plastic changes of SV fusion rates have long been thought to control complex brain processes such as working memory, but the link between presynaptic plasticity and complex brain functions remains hypothetical. A key determinant of presynaptic efficacy is that synapses maintain a release-ready or primed SV pool that can be refilled rapidly. SV priming is mediated by a set of dedicated priming proteins (Munc13s, CAPSs, and accessory proteins), which are of pervasive and essential functional importance for synaptic efficacy, and - based on in vitro studies - of capacious potential to regulate exactly the type of synaptic plasticity that is associated with brain circuit characteristics involved in complex behaviours. However, this 'catholic' role of the SV priming machinery in brain function has never been tested, mainly because essential genetic models for studies in vivo have been lacking. Using (i) 4 newly generated conditional KO and KI mouse lines, (ii) 17 additional KOs/KIs (12 ours), (iii) high-end EM approaches (iv) KO-replacement strategies, (v) electrophysiological and optophysiological analyses, and (vi) behavioural studies, we will examine the SV priming machinery in intact circuits in order to (a) define the mechanisms and cell biological basis of SV priming, of its dynamics, and of defined priming-dependent synaptic plasticity states, and to (b) define the causal links between SV priming, synapse function, synaptic plasticity, circuit characteristics, and behaviour. These studies will generate a comprehensive delineation of the role of SV priming in intact neural circuits, which is not only essential for basic science but also for psychiatry, because all key priming proteins are linked to neuropsychiatric diseases.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2015-09-01"], "Project_ID": ["670283"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 148 613"], "Project_Title": ["spim4You: customised solutions for light sheet microscopes and imaging data analysis."], "Total_Cost": ["EUR 148 613"], "Country": ["Germany", "Germany"], "Project_ACR": ["spim4You"], "Technology_Description": "Biological research heavily relies on visualization of biological samples by microscopy. In recent years light-sheet microscopy has emerged as a paradigm shifting technique. Only with light sheet microscopy it is for instance possible to follow every cell in a living system throughout development, to monitor brain activity of a live animal or to study cancer cells in their native three dimensional environment within an organism. Thus, light sheet microscopy has the potential to revolutionize biological research and in the near future every research establishment will have a light sheet microscope. During the Hourglass ERC grant, my laboratory developed two widely used open access solutions for light sheet microscopy: ", "To": ["2017-04-30, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2015 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2015-11-01"], "Project_ID": ["680901"], "Call_for_Proposal": ["ERC-2015-PoC"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 2 484 375"], "Project_Title": ["Crystalline and vitreous silica films and their interconversion"], "Total_Cost": ["EUR 2 484 375"], "Country": ["Germany", "Germany"], "Project_ACR": ["CRYVISIL"], "Technology_Description": "Silicon is the most abundant element in the earth\u2019s crust. Its oxide, silica (SiO2) is the basis for most minerals of the earth\u2019s crust, and also for a number of technological applications ranging from window glass, via electronics to catalysis. The structure of crystalline materials such as quartz or silica-based minerals is well understood due to the application of scattering techniques such as x-ray or neutron diffraction, for example, which allow accurate structure determinations. Silica, however, also forms glasses, which are amorphous or vitreous. Its structure is not well understood. In fact, diffraction techniques have only been able to deliver pair correlation functions, which reveal the density of a material around a given atom, but do not allow a detailed reconstruction of the atomic structure as in the case of crystalline materials. Until recently, a real space image of a silica glass with atomic resolution had not been recorded. Using scanning probe techniques applied to a thin silica film grown atomically flat on a metal substrate, it has been possible to reveal, for the first time, an atomically resolved image of vitreous silica. Both, a crystalline as well as a vitreous phase have been imaged. With this system, it is now possible to address the transition from a vitreous state to a crystal-line in real space by developing a scanning probe microscope that allows the study of its structure over a wide range of temperatures ranging from cryogenic temperatures to 1500 K. It is the purpose of this grant application to build such a device and apply it to the crystal-glass transition and the study of vibrational properties. This instrument may also be used to address a number of scientific problems related to other glass-formers, such as borates and the influence of silica modifications by atom doping, for example.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2016-01-01"], "Project_ID": ["669179"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 3 176 850"], "Project_Title": ["Collective modes in 4d-metal compounds and heterostructures"], "Total_Cost": ["EUR 3 176 850"], "Country": ["Germany", "Germany"], "Project_ACR": ["Com4Com"], "Technology_Description": "Compounds of transition metals with 4d valence electrons (\u201c4d metals\u201d) play eminent roles in many areas of condensed matter physics ranging from unconventional superconductivity to oxide electronics, but fundamental questions about the interplay between the spin-orbit coupling and electronic correlations at the atomic scale remain unanswered. Momentum-resolved spectroscopies of collective electronic excitations yield detailed insight into the magnitude and spatial range of the electronic correlations, and have thus decisively shaped the conceptual understanding of quantum many-body phenomena in 3d-electron systems. We will devise and build a novel resonant inelastic x-ray scattering (RIXS) instrument capable of determining the dispersion relations of electronic collective modes in 4d-metal compounds with full momentum-space coverage, high energy resolution, and monolayer sensitivity. ", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2016-01-01"], "Project_ID": ["669550"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 2 500 000"], "Project_Title": ["Novel Cells for Organ Repair"], "Total_Cost": ["EUR 2 500 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["PROMETHEUS"], "Technology_Description": "In adult organisms, the natural ability to regenerate tissues damaged by injury or aging resides in multipotent tissue-specific precursors in local microenvironments. The number of these precursors is often either limited or declines sharply with age. Moreover, long-term adverse side effects of cancer treatments affect patients of any age. Such treatments tend to diminish the stem cell and progenitor cell populations.", "To": ["2020-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2015-08-01"], "Project_ID": ["669168"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 609 375"], "Project_Title": ["Unraveling the history of adaptation in an island model: Cape Verde Arabidopsis"], "Total_Cost": ["EUR 1 609 375"], "Country": ["Germany", "Germany"], "Project_ACR": ["CVI_ADAPT"], "Technology_Description": "Islands have played a pivotal role in evolutionary theory since Darwin and Wallace. Due to their isolation, they represent natural laboratories, providing uncomplicated microcosms where fundamental principles of the evolutionary process can be revealed. One area where island systems can provide a crucial advance is in evolutionary genetics. Here, a primary goal is to reconstruct the mechanisms, mode and tempo of the evolutionary process by identifying specific adaptive functional variants and studying the historical dynamics of these in nature. However, even with recent advances in tools and technologies (e.g., affordable genome-wide sequencing, developments in genome manipulation), the complexity of most natural systems makes this a challenging task.", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2015-11-01"], "Project_ID": ["638810"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Millet and beans, language and genes. The origin and dispersal of the Transeurasian family."], "Total_Cost": ["EUR 2 000 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["Eurasia3angle"], "Technology_Description": "The question about the origin and dispersal of the Transeurasian languages (i.e. Japonic, Koreanic, Tungusic, Mongolic and Turkic) is one of the most disputed issues in linguistic history. Eurasia3angle will address this question from an interdisciplinary perspective. My key objective is to effectively synthesize linguistic, archaeological and genetic evidence in a single approach, for which I use the term \"triangulation\". To this end, my project will bring together a highly qualified interdisciplinary team of doctoral and postdoctoral researchers along with world-eminent experts, who will focus on testing the Farming/Language Dispersal Hypothesis for the Transeurasian languages. The FLDH attributes the dispersal of some of the world's major language families to the adoption of agriculture and subsequent population expansion, whereby the language of new farmers displaced that of preexisting hunter gatherers. In contrast to its application to the major language families in East Asia, the FLDH has not been tested yet for the Transeurasian languages. My research team will specifically investigate the hypothesis that the Transeurasian languages derive from a homeland in South Manchuria and that their early dispersal should be associated with the spread of cultivation of millet and beans. For this purpose, we will use advanced techniques recently introduced to the individual disciplines, such as the application of phylogenetic methods to linguistic classification, a focus on derivational morphology in the reconstruction of subsistence-related language, a matrix-based comparison of archaeological cultures and a model-based approach applied to genome-wide autosomal data. Converging these partial perspectives into a more holistic understanding of what really happened in the past is quite a challenge. However, if successful, this research will be a break-through in the investigation of human prehistory in general and in the long-standing Transeurasian debate in particular.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2015-09-01"], "Project_ID": ["646612"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Metabolic and Genetic Regulation of Ageing"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["MetAGEn"], "Technology_Description": "Ageing is a complex physiological process that affects almost all species, including humans. Despite its importance for all of us, the biology of ageing is insufficiently understood. To uncover the molecular underpinnings of ageing, I propose an interdisciplinary research program that will identify and investigate metabolic and genetic regulators of ageing.", "To": ["2020-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2015-08-01"], "Project_ID": ["640254"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 2 500 000"], "Project_Title": ["Reshuffling genes and genomes: from experimental evolution to synthetic biology in plants"], "Total_Cost": ["EUR 2 500 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["GENEVOSYN"], "Technology_Description": "GENEVOSYN has three highly ambitious objectives that will enable the engineering of new generations of crop plants. The project consists of three complementary workpackages (WPs) and will use both synthetic genomes and naturally available genomes as raw material for novel biotechnology and synthetic biology approaches. It will employ experimental gene and genome transfer as well as recently discovered natural (horizontal) genome transfer processes to generate new crop varieties and species. In WP1, the plastid (chloroplast) will be developed as a highly efficient platform for synthetic biology applications in plants. This will be accomplished by pursuing bottom-up and top-down synthetic biology approaches. They include the construction of large synthetic multigene operons towards introducing new complex metabolic pathways into plants, and the design, synthesis, assembly and booting up of radically redesigned synthetic genomes that ultimately will allow us to expand the genetic code and thereby the amino acid repertoire of plant cells. In WP2, GENEVOSYN aims at developing a technology for mitochondrial genome engineering in plants. The possibility to alter the genetic information in plant mitochondria by transformation would revolutionize both basic and applied research on plant mitochondria, and pave the way to harnessing the enormous potential of mitochondrial biotechnology. Finally, WP3 will exploit recently discovered horizontal genome transfer processes for the creation of novel crop species and the improvement of existing ones. To this end, we will use grafting-assisted horizontal genome transfer between crop species in the nightshade family (Solanaceae) to (i) generate new combinations of nuclear and plastid genomes and determine the impact of the plastid genome and specific plastid genes on plant growth and stress tolerance, and (ii) produce novel (synthetic) species that arise from the combination of entire nuclear genomes of existing species.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2015-10-01"], "Project_ID": ["669982"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 2 064 583"], "Project_Title": ["Molecular reconstitution of epigenetic centromere inheritance"], "Total_Cost": ["EUR 2 064 583"], "Country": ["Germany", "Germany"], "Project_ACR": ["RECEPIANCE"], "Technology_Description": "Accurate segregation of the parental genome to the daughter cells during mitosis is essential for cell and organismal viability, protecting against cell death or cellular transformation. Kinetochores are crucial for accurate chromosome segregation because they link chromosomes to spindle microtubules. Kinetochores sprout from unique chromosomal loci named centromeres. In most eukaryotes, centromere specification does not rely on defined DNA sequences. Rather, centromere specification relies on epigenetic mechanisms, the most prominent of which is identified in the enrichment at centromeres of the histone H3 variant CENP-A. Deposition of new CENP-A at every cell cycle is vital for centromere maintenance through cell division. RECEPIANCE aims to dissect the molecular mechanism of CENP-A deposition through reductionist approach based on two main pillars, biochemical reconstitution and structural analysis. ", "To": ["2020-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2015-08-01"], "Project_ID": ["669686"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 78 125"], "Project_Title": ["CoPIRL: Compact High Power Picosecond Infrared Laser for Scar Free Surgery and Bio-Diagnostics."], "Total_Cost": ["EUR 78 125"], "Country": ["Germany", "Germany"], "Project_ACR": ["CoPIRL"], "Technology_Description": "The PIRL concept is the first method of any to achieve surgery without scar tissue formation. This new laser concept has achieved the long held promise for the laser for attaining the fundamental limit to minimally invasive surgery. The very prospect of high precision surgery without scar tissue formation is readily appreciated to potentially revolutionize surgery and holds equally great promise in providing in situ bio-diagnostics.", "To": ["2016-12-31, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2014 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2015-07-01"], "Project_ID": ["640678"], "Call_for_Proposal": ["ERC-2014-PoC"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 499 946"], "Project_Title": ["Gut Microbiota in Nervous System Autoimmunity: Molecular Mechanisms of Disease Initiation and Regulation"], "Total_Cost": ["EUR 1 499 946"], "Country": ["Germany", "Germany"], "Project_ACR": ["GAMES"], "Technology_Description": "Multiple Sclerosis (MS), an autoimmune demyelinating disease affecting the central nervous system (CNS), causes tremendous disability in young adults and inflicts huge economic burden on the society. The incidence of MS is steadily increasing in many countries arguing for environmental factors driven changes in disease induction. How and which environmental factors contribute to disease initiation and progression is unknown. Using a spontaneous mouse model of MS, we have shown that the gut microbiota is essential in triggering CNS autoimmunity. In contrast to the mice housed in conventional housing conditions, germ free (GF) mice, devoid of gut bacteria, were protected from spontaneous experimental autoimmune encephalomyelitis (sEAE). Re-colonization of GF mice with a complex regular gut flora derived from specific pathogen free (SPF) mice resulted in sEAE within 2-3 months. The re-colonization also triggered pro-inflammatory T and B cell responses. However, colonization of GF mice with a reduced gut flora failed to induce sEAE during our observation period suggesting a \u201cspecific\u201d rather than a \u201cbroader\u201d microbial trigger. In this proposal, I want to study the role of gut microbiota in CNS autoimmunity with the following aims:", "To": ["2020-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2015-06-01"], "Project_ID": ["635617"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 266 750"], "Project_Title": ["Origins of the Molecular Cloud Structure"], "Total_Cost": ["EUR 1 266 750"], "Country": ["Germany", "Germany"], "Project_ACR": ["PROMISE"], "Technology_Description": "Understanding the physical processes that control the life-cycle of the interstellar medium (ISM) is one of the key themes in the astrophysics of galaxies today. This importance originates from the role of the ISM as the birthplace of new stars, and therefore, as an indivisible component of galaxy evolution. Exactly how the conversion of the ISM to stars takes place is intricately linked to how the internal structure of the cold, molecular clouds in the ISM forms and evolves. Despite this pivotal role, our picture of the molecular cloud structure has a fundamental lacking: it is based largely on observations of low-mass molecular clouds. Yet, it is the massive, giant molecular clouds (GMCs) in which most stars form and which impact the ISM of galaxies most. I present a program that will fill this gap and make profound progress in the field. We have developed a new observational technique that provides an unparalleled view of the structure of young GMCs. I also have developed a powerful tool to study the most important structural characteristics of molecular clouds, e.g., the probability distribution of volume densities, which have not been accessible before. With this program, the full potential of these tools will be put into use. We will produce a unique, high-fidelity column density data set for a statistically interesting volume in the Galaxy, including thousands of molecular clouds. The data set will be unmatched in its quality and extent, providing an unprecedented basis for statistical studies. We will then connect this outstanding observational view with state-of-the-art numerical simulations. This approach allows us to address the key question in the field: Which processes drive the structure formation in massive molecular clouds, and how do they do it? Most crucially, we will create a new, observationally constrained framework for the evolution of the molecular cloud structure over the entire mass range of molecular clouds and star formation in the ISM.", "To": ["2021-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2016-02-01"], "Project_ID": ["639459"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 147 094"], "Project_Title": ["Rapid and Inexpensive Diagnosis of Heparin Induced Thrombocytopenia Using Glycan Arrays Containing Synthetic Glycosaminoglycans"], "Total_Cost": ["EUR 147 094"], "Country": ["Germany", "Germany"], "Project_ACR": ["HITCHIPDIAG"], "Technology_Description": "Rapid and Inexpensive Diagnosis of Heparin Induced Thrombocytopenia Using Glycan Arrays Containing Synthetic Glycosaminoglycans Heparin, a complex glycosaminoglycan (GAG) carbohydrate, is the most commonly used anticoagulant. Twelve million patients in the EU are treated annually for conditions including acute coronary syndrome, deep-vein thrombosis and cardiopulmonary bypass surgery. Heparin-induced thrombocytopenia (HIT) is a dangerous adverse side effect of heparin administration. HIT-II develops after major surgery or dialysis and results in infarction, multi-organ failure and 20% mortality. In Europe 100,000 patients develop HIT-II annually.", "To": ["2016-09-30, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2014 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2015-04-01"], "Project_ID": ["665607"], "Call_for_Proposal": ["ERC-2014-PoC"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Structural and mechanistic study of ion transport in Channelrhodopsin-2"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["LIIT-ChR2"], "Technology_Description": "Channelrhodopsins are type-I rhodopsin proteins found in green algae that function as sensory photoreceptors and turn into ion channels under illumination. Upon light absorbance, the retinal moiety induces a conformational change on the protein that opens a channel through which ions can pass.", "To": ["2017-03-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2015-04-01"], "Project_ID": ["661784"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Modeling the chronology of deep ocean circulation changes during abrupt climate transitions"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["OCTANT"], "Technology_Description": "The deep ocean circulation affects climate and the global carbon cycle. A prerequisite for improving confidence in future climate projections is the accurate reproduction of past deep ocean circulation changes by models. However our understanding of such changes in terms of transport pathways and transit times is impeded by ambiguities in the chronology of ocean archives. This project aims at helping resolve such ambiguities by investigating to what extent the temporal evolution of the ocean circulation during abrupt climate transitions may be inferred from deep-sea sediment cores.", "To": ["2018-03-18, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2016-03-19"], "Project_ID": ["660893"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["No Biofouling Surfaces"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["NoBios"], "Technology_Description": "Biofilms consist of bacteria, proteins and cells which attached to a solid surface. Prevention of biofilms is of extreme relevance in industry and science as they are ubiquitous and able to provoke corrosion or failure in pipelines, heat exchangers, biomedical devices, artificial implants or food processing facilities. Biofilms are often battled with antibiotics, but bacterial resistance is a major problem. Therefore, novel approaches are required to avoid biofouling. We will explore the application of (1) superamphiphobic coatings, (2) slippery liquid infused porous surfaces and (3) functional pillar arrays surfaces to battle biofouling. These surfaces have in common that they strongly repel water, blood and organic liquids, and even soap-water mixtures due to a synergy between rough topography and a special chemistry. We will monitor and characterize the adhesion of bacteria, proteins and cells to these surfaces depended on shape, size and chemical of composition of the surface and the liquids. Several classical and highly advanced cutting edge methods will be used to investigate the wetting and fouling properties of these surfaces, especially laser scanning confocal microscopy. In the final steps of the research, we will evaluate the robustness of the surfaces and the biocompatibility in order to establish potential real applications in collaboration with industrial partners. We exert a high impact of this fellowship to the scientific community and the rest of society.", "To": ["2017-03-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2015-04-01"], "Project_ID": ["660523"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Experimental Studies of Strongly Interacting Quantum Gases in an Optical Lattice"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["RyM"], "Technology_Description": "Quantum gas systems have been recognized as quantum simulators that can directly compare theoretical models and experiments because of unprecedented experimental conditions. Here, we propose experimental studies on strongly interacting quantum gases in an optical lattice. The key ingredients of our research are the strong and long-range dipolar interactions from Rydberg excited states and two-component Bosonic atoms in optical lattices, which can simulate Heisenberg Hamiltonian. ", "To": ["2017-04-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2015-05-01"], "Project_ID": ["660452"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["LUNDS UNIVERSITET", "LUNDS UNIVERSITET"], "EU_Contribution": ["EUR 2 442 000"], "Project_Title": ["Towards a deepened understanding of combustion processes using advanced laser diagnostics"], "Total_Cost": ["EUR 2 442 000"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["TUCLA"], "Technology_Description": "The field of combustion is of utmost societal/industrial importance while at the same time posing outstanding scientific challenges. In order to handle these, it is extremely important to develop and apply non-intrusive laser-diagnostic techniques with high spatial and temporal resolution for measurements of key parameters such as species concentrations and temperatures. Such techniques have been developed and applied by the PI for more than thirty-five years and the home institute has one of the most advanced instrumentations in academia world-wide. ", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["669466"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "STICHTING KATHOLIEKE UNIVERSITEIT"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Greenhouse Gas Mitigation through Advanced Nitrogen Removal Technology"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Germany", "Germany", "Netherlands"], "Project_ACR": ["GREENT"], "Technology_Description": "Human activities have severe impacts on the biological carbon and nitrogen cycles. The most important consequences of these are global warming and water pollution. Wastewater treatment technology, in particular nitrogen removal systems, improved considerably in the last decade. The application of anaerobic ammonium oxidizing (anammox) bacteria in oxygen-limited granules has the potential to turn wastewater treatment plants into energy-efficient systems with minimal greenhouse gas emissions of carbon dioxide, nitrous oxide and methane. Recently, microorganisms that couple the anaerobic oxidation of methane to denitrification were discovered. An innovative integration of these microorganisms into partial nitritation-anammox systems for wastewater treatment offers an elegant and efficient solution to combat greenhouse gas emissions from wastewater treatment plants. The aim of the GREENT project is to determine nitrous oxide emissions from partial nitritation-anammox bioreactors and the parameters that govern these emissions, and to investigate the responsible pathways in molecular detail. Furthermore, I will explore the feasibility of an innovative bioreactor, which will remove ammonium and methane simultaneously through anammox and anaerobic methane-oxidizing microorganisms. This approach will turn the otherwise harmful methane into a resource for efficient nitrogen removal. These fundamental insights and technological advances will be achieved by a complimentary array of state-of-the-art methodology such as continuous culturing, stable isotope tracing and a combination of -omics methods together with physiological experiments and detailed measurements at full-scale installations. The results of this proposal will be of paramount importance for the wastewater treatment sector, but also indispensable for mathematical modelling, life cycle assessment and understanding the ecophysiology of the involved microorganisms.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["640422"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Integrin specificity in rigidity sensitive proliferation, activation and directional migration of endothelial cells"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["ISPADMEC"], "Technology_Description": "Cells have the extraordinary ability to regulate their morphology, functions and fate to minimal changes in the extracelullar microenvironment. Through multi-protein, cell-matrix adhesions they are able to recognize and respond not only to the chemical diversity of the extracellular matrix (ECM), but also to its physical and topographical features. Mechanical and structural cues encoded in the ECM have an essential role in healthy tissue function where contractility, spreading and proliferation are intricately regulated by cell-cell and cell-matrix adhesion and tension. Unsurprisingly, abnormal ECM mechanics are directly associated with disease and tissue malformation (atherosclerosis, wound healing and tumor formation). Understanding the mechanisms cells use to sense and transduce mechanical signals, as well as the contribution of key players in the process is a pressing, unmet challenge. ", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2015-09-01"], "Project_ID": ["660205"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Mitochondrial Dynamics and Local Protein Synthesis in Dendrites"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["NEUROMITO"], "Technology_Description": "Neurons are specialized cells with polarized morphology. Efficient function dictates that the molecular events crucial for synaptic communication are not centralized at the cell body but distributed to individual subcellular compartments - dendrites, dendritic spines, axons, presynaptic terminals. Local protein synthesis in dendrites is one such mechanism that plays a significant role in synaptic plasticity and memory. However, little is known on how the high-energy demands of local protein synthesis are met at dendrites and spines. Mitochondria, the 'energy houses' of cells, are found in great abundance in neurons. Mitochondria are associated with: nuclear-encoded messenger RNAs for local translation of great majority of mitochondrial proteins; non-coding RNAs for translational regulation of its protein abundance. To meet the local energy demands of protein synthesis, it is likely that mitochondria compartmentalize at dendritic regions and undergo dynamic changes in their proteome and transcriptome. My research project aims at elucidating the dynamics of mitochondria during high-energy demands of local protein synthesis. I will be performing experiments to examine mitochondrial compartmentalization in dendrites. Since simple fluorescence time-lapse imaging is not sensitive enough to visualize mitochondrial dynamics, I will use state-of-the-art imaging tools available in Dr. Erin Schuman\u2019s lab for my experiments. I will also exploit the special neuron culture platforms, Microfluidic chambers, co-invented in the Schuman lab, for this purpose. In addition, I will be performing proteomic and transcriptomic analysis of mitochondria isolated from somata and neurites. To this end, I will use the shared protein mass spectometry facility of the Max Planck Institute for Brain Research and Biophysics for mitochondrial proteomics and the advanced RNA sequencing techniques employed in the Schuman group for mitochondrial transcriptomics.", "To": ["2017-12-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2016-01-01"], "Project_ID": ["657702"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["An astrochemical study of the early evolutionary stages of sub-stellar mass objects"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["ABDES"], "Technology_Description": "Astrochemistry is an inter-disciplinary field that provides an insight into the complex physical and chemical processes at play during the early evolutionary stages in star-formation. Over the last decade, while astrochemical studies have been conducted to understand the early evolutionary stages in high- and low-mass stars, similar work is essentially missing for the least massive stars, called brown dwarfs (BDs). BDs are \u2018sub-stellar\u2019 objects with insufficient mass to burn hydrogen in their cores and shine like stars, but are found as abundantly as Sun-like stars in star-forming regions, making them an equally vital constituent of our Galaxy. ABDES is an innovative inter-disciplinary project, which will deliver radically new advancements in our understanding of the astrochemical processes that occur during the early evolutionary stages in BD-formation. The objectives of ABDES are to characterize the physical and chemical structure of early-stage BDs, and study the fundamental role played by the accretion and outflow processes in shaping their evolution. With the advent of high-class telescopes and instruments with unparalleled sensitivities, it is now feasible to probe deep into the early evolutionary stages of BDs. To achieve these objectives, I have built the largest sample to date of early-stage BDs, using a new set of deep, high-sensitivity, multi-wavelength observations. ABDES will combine these observations with chemical/physical modelling techniques, and provide the first measurements on the astrochemical properties of early-stage BDs. Being an inter-disciplinary research division, the Centre for Astrochemical Studies at MPE, under the supervision of Prof. Caselli, is a great fit to this project, and provides excellent expertise and infrastructure for its successful implementation. ABDES is a pioneering study that will highlight the origins of the faintest stars in our Galaxy, and complete our understanding of star-formation toward the lowest mass end.", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2015-09-01"], "Project_ID": ["659383"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Nonlinear optical coatings at high intensities"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["NICOS"], "Technology_Description": "Optical interference coatings have become a key enabling technology for many laser systems. Modern oscillators and amplifiers are capable of generating ultrashort pulses with energies of several tens of \u00b5J at repetition rates of more than 10 MHz, resulting in several hundreds of watts of average output power. Under the illumination of optical coatings by such intense optical fields, the nonlinear effects manifest themselves. These effects can be exploited for development of novel types of nonlinear optical (NLO) laser components: dielectric multilayer coatings with specified nonlinear properties. In order to use the potential of dielectric coatings as NLO devices, the nonlinear behaviour of dielectric multilayers at intensities which are, from one side, high enough to activate nonlinearities and lower, from other side, than laser damage threshold, has to be carefully explored. As structures of films differ from the ones of bulk materials, then characterization of nonlinear effects in dielectric coatings is to be carried out and numerical values of coatings\u2019 nonlinear parameters are be estimated.", "To": ["2017-09-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2015-10-01"], "Project_ID": ["657596"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["STIFTUNG FRANKFURT INSTITUTE FOR ADVANCED STUDIES", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 257 860,80"], "Project_Title": ["Bayesian computations in the human neocortex: deciphering the neuronal mechanisms of perceptual and syntactic inferences."], "Total_Cost": ["EUR 257 860,80"], "Country": ["Germany", "Germany"], "Project_ACR": ["BayesianHumanCortex"], "Technology_Description": "The diversity of human cognitive abilities contrasts with the homogeneity of its neural bases. Indeed, perception, decision and language processes largely rely on a common neuronal structure \u2013 the neocortex \u2013 whose functioning remains remarkably poorly understood. Recent theories suggest that the six layers of the neocortical microcircuit are specifically interconnected to perform generic computations, thanks to a Bayesian hierarchical combination of top-down expectations (priors) and bottom-up sensory information (likelihoods). However, recording each cortical layer is technically challenging. Mainly limited to animal electrophysiology, the rare empirical investigations of neocortical operations have been incapable of tackling human-specific cognitive abilities, such as syntax processing. Capitalizing on recent advances in human electrophysiology, I will address these challenges by testing whether the elements of Bayesian computations are implemented by 1) distinct cortical layers (e.g. priors in layers 5/6) or, alternatively, 2) distinct neuronal oscillations (e.g. priors in the alpha/beta band). I will then assess whether these neuronal computations form the elementary components of syntax processing. To characterize the exchange of information within and between cortical regions, I will combine whole-brain magnetoencephalography of with invasive electrocorticography and intra-laminar recordings, acquired from patients implanted for clinical purposes. This project, at the intersection of neuroscience, computational theory and linguistics will set the foundations for a mechanistic investigation of human cognition at an unprecedented level of detail, and will therefore allow me to start a competitive scientific career as an independent researcher. Ultimately, this innovative framework will help us understand the building blocks of human cognition, and the way neocortical dysfunctions lead to complex mental disorders such as schizophrenia.", "To": ["2018-07-31, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2015-08-01"], "Project_ID": ["660086"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Mechanisms of natural auto immunity triggered by plant NLR immune receptors"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["NLRs"], "Technology_Description": "Resistance (R) loci with nucleotide binding/leucine rich repeat (NB-LRR or NLR) domains have been identified as the major causal genes for hybrid necrosis, which presents an extreme example of the trade-off between plant growth and the activation of immune system. This is an exciting finding both for plant breeders and plant pathologists. However, how these NLR proteins or even the whole NLR family lead to hybrid necrosis, how they contribute to fitness under natural conditions, and how this is reflected in their extreme sequence variation remain largely unknown. In this proposal, I plan to exhaustively explore their function by systematically knocking out the NLR loci from genome of different Arabidopsis accessions using genome editing, and testing their fitness performance in the natural habitat. I will also reveal the cellular and biochemical mechanisms by which NLR proteins inappropriately interact with other cellular proteins to cause hybrid necrosis and compare the hybrid necrosis activity with pathogen induced immunity.", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2015-09-01"], "Project_ID": ["655295"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["THz Photochemistry: Biased Proton Transfer by Ultrafast Electric Fields"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["THz Photochemistry"], "Technology_Description": "Ultraviolet or visible light induces chemical transformations via electronic excitation. Infrared radiation, corresponding to low-frequency molecular vibrations, can also bring about photochemical reactions by multi-photon absorption. Then, how low photon energies can we reach in photochemistry? In this proposed research, I will realize a novel concept of terahertz photochemistry: activating chemical reactions with intense terahertz (THz) light of extremely low photon energy (1 THz = 4.1 meV).", "To": ["2017-03-31, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2015-04-01"], "Project_ID": ["658467"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Molecular Mechanisms Linking Psychological Stress and Ageing-Related Disease"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["STRESSAGED"], "Technology_Description": "Ageing-related diseases are the leading causes of morbidity and mortality. A ubiquitous and potentially preventable factor predisposing to their development is psychological stress, but the molecular mechanisms underlying this relation are largely unknown. This knowledge gap is addressed by the proposed project, which examines epigenetic modifications and, in particular, DNA methylation changes as molecular signatures that may be induced by lifetime stressors and act in concert with advancing age to shape disease risk. The proposed fellow will first identify the DNA methylation sites that are regulated by stressors and ageing and will then examine how these epigenomic sites determine gene expression and disease outcomes. Among key biological processes, the project will focus on immune dysregulation, a common pathogenic process for several diseases of the ageing. Immune dysregulation will be examined in the periphery but also in the brain, the orchestrator of behavioral, neuroendocrine and immune responses. The project will engage translational approaches using both human samples and animal models, implemented via collaborations among leading institutions and experts in Europe and USA. The applicant has unique interdisciplinary skills to carry out the project, including clinical background as well as experience in both clinical and basic research projects on the two fields brought together in the proposal, the biology of stress and ageing-related diseases. The impact of the project can be tremendous, since elucidating the molecular mechanisms of ageing-related diseases would contribute to the development of biomarkers, targeted prevention strategies and novel treatments for these devastating diseases.", "To": ["2017-04-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2015-05-01"], "Project_ID": ["653240"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Automated synthesis of S. pneumoniae 7F capsular polysaccharide repeating unit as candidate for conjugate vaccines"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["AUTOOLIGO"], "Technology_Description": "The goal of this project is to develop an automated synthesis of the Streptococcus pneumoniae 7F capsular polysaccharide repeating unit, which is of high interest for synthetic vaccines against this pathogen. This structural motif has never been synthesized yet, not even by traditional solution techniques. Our approach is highly innovative in the application of automated oligosaccharide synthesis, which will make the synthetic procedure more time- and cost-effective. ", "To": ["2017-03-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2015-04-01"], "Project_ID": ["652745"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Decoding the DNA damage signalling in C. elegans by proteomic analyses of ADP-ribosylation"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["InVivo_DDR_ADPR"], "Technology_Description": "Preservation of genome integrity and stability is critical for survival and propagation of individuals and species. Organisms have thus evolved rapid and efficient mechanisms -collectively termed the DNA damage response (DDR)- to combat threats posed by DNA damage. Among these, the post-translational modification (PTM) ADP-ribosylation (ADPR) plays a decisive role in effective DDR. Although much is known about the relevance of ADPR upon DNA injury, the underlying molecular mechanisms are still poorly understood and no systematic, unbiased proteome-wide study to determine ADPR targets in vivo has been conducted to date. The most challenging and innovative goal of this proposal is to profile in vivo ADP-ribosylated peptides during DDR in the well-established model system Caenorhabditis elegans by the combined application of advanced proteomic approaches. I will develop novel enrichment strategies that will allow me to confidently map for the first time all the sites of ADPR throughout the C. elegans proteome. I will take advantage of SILAN technology, which allows stable isotope labelling in C. elegans, to determine the quantitative profiles of thousands of ADPR sites during DDR. By bioinformatic analysis, I will select candidate proteins for further investigation of the biological role of DNA damage-induced ADPR. I will then test the biological impact of ADPR of these candidates through site-specific mutation of their identified modification sites. Finally, I will perform biochemical, molecular and functional experiments to study how ADPR alters the activity of these proteins and thereby characterize the mode of ADPR action. Understanding the regulatory networks that underlie such a complex biological process at the organism level will provide new insights for improved treatment of DNA damage-related diseases including cancer. This is an ambitious, innovative, cross-disciplinary project at the forefront of two exciting fields, biology and proteomics.", "To": ["2018-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2016-04-01"], "Project_ID": ["657501"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 616 050"], "Project_Title": ["From Cloud to Star Formation"], "Total_Cost": ["EUR 1 616 050"], "Country": ["Germany", "Germany"], "Project_ACR": ["CSF"], "Technology_Description": "Star Formation is a hierarchical process from the build-up of large clouds to the assembly of stars. This ERC project aims at studying the multi-scale processes of this conversion from diffuse gas to stars. The fundamental data are provided by two PI-led large observing programs at two of the most advanced radio and mm interferometers, the Very Large Array (VLA) and the Plateau de Bure Interferometer (PdBI). This combined approach is designed to address outstanding key questions in the field of cloud and star formation.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2015-09-01"], "Project_ID": ["648505"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Quantifying the effects of interacting nutrient cycles on terrestrial biosphere dynamics and their climate feedbacks QUINCY"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["QUINCY"], "Technology_Description": "Nutrient availability plays a pivotal role in the response of terrestrial ecosystems to increasing atmospheric CO2 and climate change. The global role of nutrients is only poorly understood quantitatively, limiting the predictive understanding of terrestrial biosphere - climate feedbacks. The first generation of global nutrient-carbon cycle models shows strongly diverging estimates of the nutrient effect, resulting from lacking integration of ecosystem observations and fundamental uncertainties in the representation of governing processes. The objective of QUINCY is to clarify the role of the interacting terrestrial nitrogen and phosphorus cycles and their effects on terrestrial C allocation and residence times as well as terrestrial water fluxes. QUINCY will create a novel, predictive framework founded on the principle of resource optimisation, shifting the paradigm of terrestrial biosphere modelling towards an active biological control of matter flows. QUINCY\u2019s main themes are (i) the effects of nutrient availability on plant photosynthesis and respiration, explicitly taking the energy requirement of nutrient acquisition into account, and (ii) the effects of vegetation-soil interactions, namely rhizosphere processes, on plant nutrient availability and soil C turnover. To corroborate these theoretical concepts, QUINCY will synthesise existing and ongoing ecosystem monitoring and manipulation studies. To specifically test emerging hypotheses on the effects of rhizosphere priming on soil C storage and plant nutrition - and to provide currently lacking data for soil-vegetation models - QUINCY will establish a tree mesocosm, elevated CO2 experiment. The novel model concepts will be consistently integrated to form a new general terrestrial biosphere model. For the first time, QUINCY will be able to address the multiway interactions of carbon, nitrogen, phosphorus and water cycles globally in a theoretically well-founded way commensurate with ecosystem observations.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2015-09-01"], "Project_ID": ["647204"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 499 904"], "Project_Title": ["Unraveling interstellar chemistry with broadband microwave spectroscopy and next-generation telescope arrays"], "Total_Cost": ["EUR 1 499 904"], "Country": ["Germany", "Germany"], "Project_ACR": ["ASTROROT"], "Technology_Description": "The goal of the research program, ASTROROT, is to significantly advance the knowledge of astrochemistry by exploring its molecular complexity and by discovering new molecule classes and key chemical processes in space. So far, mostly physical reasons were investigated for the observed variations in molecular abundances. We here propose to study the influence of chemistry on the molecular composition of the universe by combining unprecedentedly high-quality laboratory spectroscopy and pioneering telescope observations. Array telescopes provide new observations of rotational molecular emission, leading to an urgent need for microwave spectroscopic data of exotic molecules. We will use newly developed, unique broadband microwave spectrometers with the cold conditions of a molecular jet and the higher temperatures of a waveguide to mimic different interstellar conditions. Their key advantages are accurate transition intensities, tremendously reduced measurement times, and unique mixture compatibility. ", "To": ["2020-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2015-05-01"], "Project_ID": ["638027"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Origin and Protection of Unstable Repetitive DNA Elements During Sexual Reproduction"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["URDNA"], "Technology_Description": "The objective of this proposal is to define the molecular basis behind the origin and protection of unstable repetitive DNA sequences during sexual reproduction. Eukaryotic genomes contain large amounts of repetitive elements that serve vital roles in cellular physiology. However, repetitive elements are intrinsically unstable, which is caused by a high likelihood for incorrect repair when DNA breaks form within repetitive elements. During sexual reproduction, numerous DNA breaks are actively introduced into the genome, and repetitive sequences particularly threaten genome stability during this specialized developmental program. ", "To": ["2020-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2015-05-01"], "Project_ID": ["638197"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 499 700"], "Project_Title": ["Dynamic Nanoplasmonics"], "Total_Cost": ["EUR 1 499 700"], "Country": ["Germany", "Germany"], "Project_ACR": ["Dynamic Nano"], "Technology_Description": "The key component of nanoplasmonics is metals. When metal nanoparticles are placed in close proximity, the possibility of shaping and controlling near-field and far-field optical properties expands enormously. Near-field coupling between metal nanoparticles is extremely sensitive to nanometer conformational changes. Such strong dependence on conformation provides unique opportunities in manipulating optical response on the nanoscale. Simultaneously, it also raises significant challenges in realization of dynamic plasmonic systems, which can exhibit immediate conformational changes upon a regulated physical or chemical control input. ", "To": ["2020-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2015-04-01"], "Project_ID": ["638001"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 497 125"], "Project_Title": ["Fuel from sunlight: Covalent organic frameworks as integrated platforms for photocatalytic water splitting and CO2 reduction"], "Total_Cost": ["EUR 1 497 125"], "Country": ["Germany", "Germany"], "Project_ACR": ["COFLeaf"], "Technology_Description": "The efficient conversion of solar energy into renewable chemical fuels has been identified as one of the grand challenges facing society today and one of the major driving forces of materials innovation.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2015-09-01"], "Project_ID": ["639233"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 499 750"], "Project_Title": ["Quantitative analysis of Nodal/Lefty-mediated pattern formation"], "Total_Cost": ["EUR 1 499 750"], "Country": ["Germany", "Germany"], "Project_ACR": ["QUANTPATTERN"], "Technology_Description": "How an initially homogenous population of cells self-organizes to form patterned embryos and tissues is a long-standing mystery in the field of developmental biology. Understanding such self-organizing processes is of central importance for regenerative medicine and would inform approaches to transform embryonic stem cells into complex multicellular structures for human tissue replacement. The influential reaction-diffusion model postulates that patterns emerge during development under the influence of poorly diffusive activators and highly diffusive inhibitors, and we have recently found biophysical evidence supporting the differential diffusivity of the activator Nodal and its inhibitor Lefty in zebrafish embryos. While we have begun to define the Nodal/Lefty activator-inhibitor pair as a reaction-diffusion system that can transform a uniform field of cells into an embryo, three important questions remain: First, how is the differential diffusivity of activators and inhibitors achieved in living embryos? The molecular weights of activator and inhibitor proteins are too similar to explain the difference in diffusivities. Second, how do reaction-diffusion systems adapt to tissue size? Embryos can vary considerably in size, but the proportions of their body plans are remarkably constant. How reaction-diffusion systems mediate this scale-invariant patterning in vivo is unknown. Third, how do reaction-diffusion systems self-organize? Embryos are often born with maternally provided prepatterns, and it is unknown whether reaction-diffusion systems also form relevant patterns in the absence of such prepatterns. We will address these questions in zebrafish and mouse embryonic stem cells by combining innovative quantitative experimentation and mathematical modeling. This high-risk/high-gain approach will allow us to unravel general principles underlying self-organizing processes and will inform new strategies for human tissue engineering from embryonic stem cells.", "To": ["2020-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2015-07-01"], "Project_ID": ["637840"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["The mechanism of sleep control through a sleep-active sleep-promoting neuron"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["SLEEPCONTROL"], "Technology_Description": "Sleep is essential for human and animal life and is broadly conserved. The nervous system induces sleep through the activation of sleep-active sleep-promoting neurons but the key mechanisms of sleep control remain to be elucidated. Recent work from my lab showed that the C. elegans nervous system contains a single sleep-active sleep-promoting neuron, called RIS, which is GABAergic and peptidergic as is its vertebrate counterpart. C. elegans shows sleep behavior and allows the easy combination of behavioral assays with functional neural imaging and genetics. Here I propose to study the single neuron RIS as a highly simplified model of a sleep-active neuron. This is a unique and novel approach to sleep research and my expertise on sleep behavior in C. elegans puts me into a pole position to study sleep. I will elucidate the molecular mechanism of activation of sleep-active neurons, analyze the mechanism of homeostasis of sleep-active neurons, and determine the molecular mechanisms by which sleep-active neurons induce sleep in the nervous system. I will combine transcriptional profiling of sleep-active neurons with physiological assays such as functional neural imaging, genetic screening, optogenetics, and functional molecular analysis of mutants. Using the highly simplified C. elegans model, I will boost sleep research and gain mechanistic insight into the regulation of sleep behavior through sleep-active neurons. This will be the first time that sleep-active neurons have been dissected in this way and I expect to identify novel conserved molecular and circuitry mechanisms. This work should provide the basis for understanding the more complex systems that control sleep in vertebrates and for understanding human sleep disorders.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2015-09-01"], "Project_ID": ["637860"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 746 038"], "Project_Title": ["combining SYnthetic Biology and chemistry to create novel CO2-fixing enzymes, ORGanelles and ORGanisms"], "Total_Cost": ["EUR 1 746 038"], "Country": ["Germany", "Germany"], "Project_ACR": ["SYBORG"], "Technology_Description": "Carbon dioxide (CO2) is a potent greenhouse gas whose presence in the atmosphere is a critical factor for global warming. At the same time atmospheric CO2 is a cheap and readily available carbon source that can in principle be used for the synthesis of biomass/biofuels and value-added products. However, as synthetic chemistry lacks suitable catalysts to functionalize the CO2-molecule, there is an increasing need to exploit the CO2-fixing mechanisms offered by Nature for applications at the interface of chemistry and biology. This proposal is centered on reductive carboxylation, a completely novel principle of enzymatic CO2-fixation that we discovered only recently and that is one of the most efficient CO2-fixation reactions described in biology so far. First, we will focus on understanding the novel principle of reductive carboxylation, by studying its catalysis at molecular scale and single step resolution. This will allow us to derive the first detailed catalytic framework for highly efficient CO2-fixation and enable us to engineer novel carboxylation reactions and products. Second, we will establish a new in vitro platform for the assembly and optimization of artificial (\"synthetic\") CO2-fixation pathways that are based on reductive carboxylation and that have been calculated to be kinetically and bioenergetically favored compared with naturally existing CO2-fixation pathways. This platform closes a long-standing gap between the theory and practice of synthetic pathway design, and will be used to develop the first functional in vitro module for CO2-fixation, a \"synthetic organelle\". Finally, we will realize synthetic CO2-fixation in selected biological model systems. To that end, we will implement the optimized in vitro pathways in isolated chloroplasts, as well as alpha-proteobacterial hosts to create novel CO2-fixing organelles and organisms, breaking new grounds in understanding and engineering biological systems for efficient CO2-fixation.", "To": ["2020-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2015-05-01"], "Project_ID": ["637675"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["TEL AVIV UNIVERSITY", "TEL AVIV UNIVERSITY"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Assay for cancer diagnostics by quantification of 5hmC"], "Total_Cost": ["EUR 150 000"], "Country": ["Israel", "Israel"], "Project_ACR": ["OR-HMC"], "Technology_Description": "Assay for cancer diagnostics by quantification of 5hmC", "To": ["2019-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["767931"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["EUROPEAN RESEARCH INFRASTRUCTURE CONSORTIUM FOR THE SURVEY OF HEALTH, AGEING AND RETIREMENT IN EUROPE"], "EU_Contribution": ["EUR 5 493 328"], "Project_Title": ["Achieving world-class standards in all SHARE countries"], "Total_Cost": ["EUR 5 493 328,75"], "Country": ["Germany"], "Project_ACR": ["SHARE-DEV3"], "Technology_Description": "The central objective of this project is to improve European coverage, stability and cross-national comparability of SHARE, the Survey of Health, Ageing and Retirement in Europe, while a sustainable funding model will be negotiated with the member states, DG RTD, DG JRC and several policy-related DGs to fully implement SHARE-ERIC in all SHARE countries.", "To": ["2018-06-30, ongoing project |"], "Meta": [""], "Topic_s": ["INFRADEV-3-2015 - Individual implementation and operation of ESFRI projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations"], "From": ["2015-07-01"], "Project_ID": ["676536"], "Call_for_Proposal": ["H2020-INFRADEV-1-2015-1"]}, -{"Partners": ["FUNDACAO D. ANNA SOMMER CHAMPALIMAUD E DR. CARLOS MONTEZ CHAMPALIMAUD"], "EU_Contribution": ["EUR 160 635,60"], "Project_Title": ["From surrogate hemodynamics-based fMRI towards direct functional imaging of neural activity via sensing activity-induced cell swellings and neurotransmitter releases in vivo"], "Total_Cost": ["EUR 160 635,60"], "Country": ["Portugal"], "Project_ACR": ["SPECIFIC fMRI"], "Technology_Description": "Functional-Magnetic Resonance Imaging (fMRI) has transformed our understanding of brain function due to its ability to noninvasively tag \u2018active\u2019 brain regions. Nevertheless, fMRI only detects neural activity indirectly, by relying on slow hemodynamic couplings whose relationships with underlying neural activity are not fully known. ", "To": ["2017-03-31, Grant Agreement terminated |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Portugal"], "Activity": ["Research Organisations"], "From": ["2015-04-01"], "Project_ID": ["657366"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 988 100"], "Project_Title": ["Atomic-Scale Dynamics of Quantum Materials"], "Total_Cost": ["EUR 1 988 100"], "Country": ["Germany", "Germany"], "Project_ACR": ["dasQ"], "Technology_Description": "Quantum materials exhibit strong electron-electron interaction, which gives rise to such remarkable phenomena as high temperature superconductivity and colossal magnetoresistance. These materials mark one of the frontiers of modern condensed matter physics: a new class of solids where many-body physics dominates. By understanding quantum materials a new generation of devices may become available, greatly boosting our ability to handle information or harvest energy. ", "To": ["2020-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2015-06-01"], "Project_ID": ["633818"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["THE UNIVERSITY OF SHEFFIELD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "Teknologian tutkimuskeskus VTT Oy", "AARHUS UNIVERSITET", "LEIBNIZ-INSTITUT FUR POLYMERFORSCHUNG DRESDEN EV", "UNIVERSIDADE NOVA DE LISBOA", "INSTITUTO DE TECNOLOGIA QUIMICA E BIOLOGICA - UNIVERSIDADE NOVA DE LISBOA", "OXFORD BIOMATERIALS LIMITED", "SPINNOVA OY"], "EU_Contribution": ["EUR 3 741 870,25"], "Project_Title": ["FLow Induced Phase Transitions, A new low energy paradigm for polymer processing"], "Total_Cost": ["EUR 3 741 871,25"], "Country": ["United Kingdom", "United Kingdom", "Finland", "Denmark", "Germany", "Portugal", "Portugal", "United Kingdom", "Finland"], "Project_ACR": ["FLIPT"], "Technology_Description": "Currently there is no truly sustainable pathway for the production of plastics, an industry which in the EU employs 1.45M people, has a turnover of \u20ac89B but consumes ~778GWh of energy per annum. This is an opportunity for industry with pressure increasing to develop low energy, high-quality, wet-processing techniques for consumer products. Here Nature may provide us with inspiration, as over hundreds of millions of years, it has evolved numerous strategies for efficient processing of its materials. One such solution has been recently hypothesised in natural silk spinning: FLIPT: FLow Induced Phase Transitions, a disruptive process which we believe could hold the key to a new low energy paradigm for polymer processing. Our research is promising, as it has already shown that silk is at least 1000 times more efficient at processing than a standard polymer (HDPE).", "To": ["2019-08-31, ongoing project |"], "Meta": [""], "Topic_s": ["FETOPEN-1-2014 - FET-Open research projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-09-01"], "Project_ID": ["713475"], "Call_for_Proposal": ["H2020-FETOPEN-2014-2015-RIA"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET", "UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK", "SIRIUS ANALYTICAL INSTRUMENTS LTD", "Pfizer Limited", "PARAYTEC LIMITED"], "EU_Contribution": ["EUR 216 000"], "Project_Title": ["Driving innovation in pharmaceuticals: integrated studies of physical dissolution properties of crystalline and amorphous forms using enhanced orthogonal monitoring techniques"], "Total_Cost": ["EUR 216 000"], "Country": ["Denmark", "Ireland", "United Kingdom", "United Kingdom", "United Kingdom"], "Project_ACR": ["CRYDIS"], "Technology_Description": "The CRYDIS exchange programme will establish and support international and inter-sectoral transfer of knowledge and expertise in pharmaceutical and instrument science between several EU research institutes and industrial companies. It will also enhance understanding of the value of inter-sectoral exchange mechanisms for taking research to market.", "To": ["2017-12-31, closed project |"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["644056"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON", "BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY"], "EU_Contribution": ["EUR 241 169,40"], "Project_Title": ["Decoding memory processing from experimental and spontaneous human brain activity using intracranial electrophysiological recordings and machine learning based methods."], "Total_Cost": ["EUR 241 169,40"], "Country": ["United Kingdom", "United States"], "Project_ACR": ["DecoMP_ECoG"], "Technology_Description": "Despite the critical importance of memory for cognitive function and socialization, very little is known about how information is stored for later retrieval and use. Understanding how the human brain maintains and stores information would enhance research on memory dysfunction in degenerative diseases, such as the age-related dementias, which represent a large burden for European society, and could facilitate the development of strategies for improving memory.", "To": ["2018-11-21, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-07-01"], "Project_ID": ["654038"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["FACULDADE DE CIENCIAS MEDICAS DA UNIVERSIDADE NOVA DE LISBOA", "UNIVERSIDADE NOVA DE LISBOA"], "EU_Contribution": ["EUR 160 635,60"], "Project_Title": ["Mechanisms of synaptic growth and plasticity"], "Total_Cost": ["EUR 160 635,60"], "Country": ["Portugal", "Portugal"], "Project_ACR": ["Neuronal Trafficking"], "Technology_Description": "My long-term goal is to understand the cellular and molecular mechanisms that govern synaptic growth and plasticity, and how dysfunction in these pathways contributes to disease. Neurons are the most morphologically diverse cell type whose morphology determines many functional aspects of a neuronal network. The primary shape of a neuron is established during axon and dendrite outgrowth and synapse formation, but is subject to subsequent modifications by physiological events. In response to changes in synaptic activity, neurons can alter both pre and postsynaptic elements of the synapse. Defects in synaptic morphology and in activity-dependent plasticity are a hallmark of several neurodegenerative and cognitive disorders. It is therefore critical to know the basic mechanisms by which neurons acquire their shape and change it in response to activity, and to dissect the genes that regulate these processes. To address these questions, this proposal is divided in the following aims:", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Portugal"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["661543"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER", "UNIVERSIDADE NOVA DE LISBOA", "INSTITUTO SUPERIOR DE ESTATISTICA E GESTAO DE INFORMACAO DA UNIVERSIDADE NOVA DE LISBOA - NOVA INFORMATION MANAGEMENT SCHOOL", "UNIVERSITAT JAUME I DE CASTELLON"], "EU_Contribution": ["EUR 3 677 229"], "Project_Title": ["Joint Doctorate in Geoinformatics - Enabling Open Cities"], "Total_Cost": ["EUR 3 677 229"], "Country": ["Germany", "Portugal", "Portugal", "Spain"], "Project_ACR": ["GEO-C"], "Technology_Description": "Urbanisation has been a key trend for centuries and is expected to continue throughout the 21st century as well. Cities have to continuously strive to provide a sustainable, safe and liveable environment for their ever-increasing populations. In recent years, the term \u2018smart cities\u2019 has been coined for initiatives that monitor and analyse different aspects of urban life, and manage service provision intelligently. A key gap in this area relates to how people can understand the processes driving smart cities and their services, and how they can gain a sense of control rather than being controlled by the services provided by a smart city. GEO-C aims to contribute methods and tools to realise smart and open cities, in which all groups of society can participate on all levels and benefit in many ways. The complementary strands of research in GEO-C will lead to an improved understanding of how to build open cities and will produce a prototypical open city toolkit. The toolkit will contain software, libraries, apps and frameworks that enable cities to easily set up or adapt key services, processes and analyses. This research area provides challenging and rewarding topics for early-stage researchers to carry out a PhD. These topics include, for example, participation across all ages and groups of society, the assessment of the quality of life, and fundamental urban services. As the 15 PhD researchers will become experts in the toolkit, their career perspectives will benefit greatly from the toolkits\u2019 public and open release. To further increase the impact of GEO-C and to also optimise career perspectives of the PhD researchers, the city councils of M\u00fcnster, Castell\u00f3n, and Lisbon and several companies across Europe will be closely involved as associated partners. They provide input to the toolkit, host early-stage researchers, and drive the use of the toolkit and the realisation of open cities as envisioned by GEO-C.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-EJD - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-EJD)"], "Funding_scheme": ["MSCA-ITN-EJD - European Joint Doctorates"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-01-01"], "Project_ID": ["642332"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["STOCKHOLMS UNIVERSITET"], "EU_Contribution": ["EUR 185 857,20"], "Project_Title": ["Sources and atmospheric processing of carbonaceous aerosol in East Asia"], "Total_Cost": ["EUR 185 857,20"], "Country": ["Sweden"], "Project_ACR": ["EastAsiaAerosol"], "Technology_Description": "High loading of carbonaceous aerosols from residential combustion of coal and wood fuels, traffic, industry, and biomass burning pollute the air of East Asia. The resulting Atmospheric Brown Clouds (ABC) are in wintertime warming the atmosphere yet dimming the surface in this vast region with severe impact on the climate, food and water security as well as air quality. Although these short-lived climate pollutant (SLCP) aerosols attract large interests across the science-policy interface, efficient mitigation actions are hampered by the limited understanding of the relative contributions of different sources of combustion-derived carbonaceous aerosols and of their subsequent atmospheric processing. Here the relative contribution from fossil fuel and biomass combustion will be quantified by molecular combustion markers and powerful isotopic fingerprinting, including microscale-14C dating of BC and OC aerosols. Aerosol samples will be probed from recently established Sino-Swedish observational program in the four populated and industrialization hotspots in China (North China Plain \u2013 Beijing; Yangtze River Delta \u2013 Shanghai; Pearl River Delta \u2013 Guangzhou; Szechuan Basin\u2013 Chengdu) and from the SE Yellow Sea recipient site on a Jeju Island (Korea Climate Observatory \u2013 Gosan), providing an ideal context for these investigations. The molecular/isotopic fingerprints of such synoptic aerosol samples provide integrated source signature and possibility to assess atmospheric processing during over-ocean long-range transport. This field quantification of BC and OC sources and processing in E Asia will contribute to (a) top-down observation-based test and improvement of bottom-up technology-based emission inventories (uncertain for small-scale and open combustion); (b) improved aerosol parameterization in climate and air quality models, and (c) scientific underpinning for policy makers to make efficient mitigation actions toward decreasing anthropogenic aerosol emissions.", "To": ["2017-04-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-05-01"], "Project_ID": ["659529"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["MUSEE ROYAL DE L'AFRIQUE CENTRALE"], "EU_Contribution": ["EUR 172 800"], "Project_Title": ["Rwenzori Ice Dynamics and Environmental Changes"], "Total_Cost": ["EUR 172 800"], "Country": ["Belgium"], "Project_ACR": ["RIDEC"], "Technology_Description": "At the border between Uganda and the D.R. of Congo, the Rwenzoris form a remote and high-altitude mountain range stretching through the East African Rift System. With heights of 4-5 km, they include Africa's third highest peak (Mt. Stanley, 5109 m) as well as some of the last African glaciers. The combined area of the Rwenzori glaciers declined by more than 75% during the 20th century, and halved between 1987 and 2006. This extreme mass loss may have strong implications for the local hydrology, ecosystems and communities, and recent estimates suggest that the glaciers will disappear in the next decade(s). This trend correlates well with similarly dramatic glacier retreats on Mt Kilimandjaro (Tanzania) and Mt Kenya (Kenya) during the same period, and is attributed to increased air temperature or reduced humidity/cloud cover. Despite recent work on the evolution of glacier extent in the last decades, the measured glacier retreat, as well as the interpretation of the driving climatic factors responsible since the 1980\u2019s, remain controversial and are limited to available data.", "To": ["2017-09-06, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["Belgium"], "Activity": ["Research Organisations"], "From": ["2015-09-07"], "Project_ID": ["656847"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSIDADE DA BEIRA INTERIOR", "BRUNEL UNIVERSITY LONDON", "POLITECHNIKA SLASKA", "ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA", "UNIVERSIDAD DE GRANADA", "UNIVERSITY OF STRATHCLYDE", "ALSITEK LIMITED", "SOFALCA SOCIEDADE CENTRAL DE PRODUTOS DE CORTICA LIMITADA", "BEIRA SERRA - ASSOCIACAO PROMOTORADO DESENVOLVIMENTO RURAL INTEGRADO", "Refractarios ALFRAN, S.A."], "EU_Contribution": ["EUR 567 000"], "Project_Title": ["Reuse of mining waste into innovative geopolymeric-based structural panels, precast, ready mixes and insitu applications"], "Total_Cost": ["EUR 567 000"], "Country": ["Portugal", "United Kingdom", "Poland", "Italy", "Spain", "United Kingdom", "United Kingdom", "Portugal", "Portugal", "Spain"], "Project_ACR": ["REMINE"], "Technology_Description": "The construction sector, currently in crises in some countries due to the economic development model adopted during last decades, can again play an important role for the European economy to be more innovative by using fewer resources (raw materials and energy) and reducing environmental impact (emission of greenhouse gases and dust pollution). Access to raw materials and resource efficiency are at the forefront of the EU political debate and recycling is a main part of the solution of many strategic objectives. It addresses resource scarcity and enhances security of material supply, while contributing to higher energy efficiency and lower environmental impacts. Moreover, recycling offers significant investment, innovation and employment opportunities in the EU. In this context, this RISE programme aims to promote international and inter-sector collaboration through research and innovation staff exchanges, share knowledge and ideas from research to market (and vice-versa) for the advancement of science and the development of innovation within the recycling and valorization of mining and quarrying wastes which represent 27% of the EU total waste generated from economic activities and households, promote utilization of innovative geopolymeric materials in the construction sector, and foster a shared culture of research and innovation that welcomes and rewards creativity and entrepreneurship and helps turn creative ideas into innovative products, services or processes in the materials industry through recycling mining wastes, by taking advantage of the integrated knowledge acquired in the complementary areas of the RISE partners. In this scenario, this RISE action aims at taking advantage of the recent developments in the areas of materials science, processing engineering, structural engineering, infrastructure systems, arts and design and market perspectives, turning mining waste into valuable materials for infrastructure and building products.", "To": ["2018-12-31, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Portugal"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["645696"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["UNIVERSIDADE NOVA DE LISBOA", "FACULDADE DE CIENCIAS SOCIAIS E HUMANAS DA UNIVERSIDADE NOVA DE LISBOA"], "EU_Contribution": ["EUR 160 635,60"], "Project_Title": ["Analysis of the Artistic Exchanges in the Medieval Mediterranean between 12th and 15th Centuries through the Geographical Information Systems (GIS): A Critical Review of Centre and Peripheries"], "Total_Cost": ["EUR 160 635,60"], "Country": ["Portugal", "Portugal"], "Project_ACR": ["ArtMedGIS"], "Technology_Description": "The aim of this research project is to evaluate the artistic exchanges in the Mediterranean during the late Middle Ages through the Geographical Information Systems (GIS). The start point is the selection of certain elements of the Islamic art, developed by the Almoravids in the 12th century. It is assumed that Almoravid arts and architecture were not isolated and can be related to other Mediterranean artistic manifestations due to commercial, political and cultural relations. In this context, the objectives of the project are: to measure the presence of the pre-selected elements in the main artistic manifestations of the Islamic and Christian Mediterranean countries in the late Middle Ages, to apply the new method based on the GIS, through the creation of three databases for studying the exchanges between the main Mediterranean artistic manifestations and Almoravid art, to assess the relation of religion and power with the artistic productions of the Islamic countries in the Mediterranean frame and to review the concepts of centre and peripheries regarding the artistic production in the Mediterranean context.", "To": ["2018-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Portugal"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["699818"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSIDADE NOVA DE LISBOA", "FACULDADE DE CIENCIAS SOCIAIS E HUMANAS DA UNIVERSIDADE NOVA DE LISBOA"], "EU_Contribution": ["EUR 160 635,60"], "Project_Title": ["QUANTIFYING THE IMPACT OF TRANSPORT INFRASTRUCTURES:NETWORK ANALYSIS APPLIED TO THE DIACHRONICALLY STUDYOF THE IBERIAN PENINSULA (From Roman Times to XIXth Century)"], "Total_Cost": ["EUR 160 635,60"], "Country": ["Portugal", "Portugal"], "Project_ACR": ["Mercator-e"], "Technology_Description": "The impact of the transport infrastructures in the development of countries and territories is one of the most current topics in the European policies. The Mercator-e project is designed to analyse the diachronic social, political and economical repercussions of the transport infrastructures during several periods of the Iberian Peninsula. An integrated approach joining multi-proxy analysis (SNA applied to the network centrality, TNA to analyse transport costs & times, demography studies) and the study of archaeo-historical sources will be applied. Analysing the transport communication networks in various time scopes will offer to the academic society new quantified data about the infrastructures morphology and their impact in the political and economical evolution of these territories. Historically, the Iberian Peninsula has had periods with very different political ideologies about the role and needs of infrastructure that will be analysed in this project: 1) The Roman era, 2) The Middle Ages, 3) the Modern Era, and 4) The XIXth Century and the emergence of the railroad.", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Portugal"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["706260"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSIDADE NOVA DE LISBOA", "INSTITUTO DE TECNOLOGIA QUIMICA E BIOLOGICA - UNIVERSIDADE NOVA DE LISBOA", "UNIVERSIDADE NOVA DE LISBOA", "INSTITUTO DE TECNOLOGIA QUIMICA E BIOLOGICA - UNIVERSIDADE NOVA DE LISBOA"], "EU_Contribution": ["EUR 1 795 967,50"], "Project_Title": ["Development of biomaterials through mimesis of plant defensive interfaces to fight wound infections"], "Total_Cost": ["EUR 1 795 967,50"], "Country": ["Portugal", "Portugal", "Portugal", "Portugal"], "Project_ACR": ["MIMESIS"], "Technology_Description": "Fighting microbial infection of wounds, especially in immunocompromised patients, is a major challenge in the 21st century. The skin barrier is the primary defence against microbial (opportunistic) pathogens. When this barrier is breached even non-pathogenic fungi may cause devastating infections, most of which provoked by crossover fungi able to infect both plant and humans. Hence, diabetic patients (ca. 6.4% of the world population), who are prone to develop chronic non-healing wounds, constitute a major risk group. My research is driven by the vision of mimicking the functionality of plant polyesters to develop wound dressing biomaterials that combine antimicrobial and skin regeneration properties.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Portugal"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["647928"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["KUNGLIGA TEKNISKA HOEGSKOLAN", "KUNGLIGA TEKNISKA HOEGSKOLAN"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Boundary value problems for nonlinear integrable equations"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["BOPNIE"], "Technology_Description": "The purpose of this project is to develop new methods for solving boundary value problems (BVPs) for nonlinear integrable partial differential equations (PDEs). Integrable PDEs can be analyzed by means of the Inverse Scattering Transform, whose introduction was one of the most important developments in the theory of nonlinear PDEs in the 20th century. Until the 1990s the inverse scattering methodology was pursued almost entirely for pure initial-value problems. However, in many laboratory and field situations, the solution is generated by what corresponds to the imposition of boundary conditions rather than initial conditions. Thus, an understanding of BVPs is crucial. ", "To": ["2021-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["682537"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["UNIVERSITAET LEIPZIG", "UNIVERSITAET LEIPZIG"], "EU_Contribution": ["EUR 1 498 620"], "Project_Title": ["ECOSYSTEM RESPONSES TO EXOTIC EARTHWORM INVASION IN NORTHERN NORTH AMERICAN FORESTS"], "Total_Cost": ["EUR 1 498 620"], "Country": ["Germany", "Germany"], "Project_ACR": ["ECOWORM"], "Technology_Description": "Earth is experiencing substantial biodiversity losses at the global scale, while both species gains and losses are occurring locally and regionally. Nonrandom changes in species distributions could profoundly influence ecosystem functions and services. However, few experimental tests have examined the influences of invasive ecosystem engineers, which can have disproportionally strong impacts on native ecosystems. Invasive earthworms are a prime example of ecosystem engineers that influence many ecosystems around the world. In particular, European earthworms invading northern North American forests may cause simultaneous species gains and losses with significant consequences for essential ecosystem processes like nutrient cycling and crucial services like carbon sequestration. Using a synthetic combination of field observations, field experiments, lab experiments, and meta-analyses, the proposed work will be the first systematic examination of earthworm effects on relationships between plant communities, soil food webs, and ecosystem processes. Further, effects of a changing climate on the spread and consequences of earthworm invasion will be investigated. Meta-analyses will be used to test if earthworms cause invasion waves, invasion meltdowns, habitat homogenization, and ecosystem state shifts. Global data will be synthesized to test if the relative magnitude of effects differ from place to place depending on the functional dissimilarity between native soil fauna and exotic earthworms. Moving from local to global scale, the present proposal examines the influence of earthworm invasions on biodiversity\u2013ecosystem functioning relationships from an aboveground\u2013belowground perspective. This approach is highly innovative as it utilizes exotic earthworms as an exciting model system that links invasion biology with trait-based community ecology, global change research, and ecosystem ecology, pioneering a new generation of biodiversity\u2013ecosystem function research.", "To": ["2021-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["677232"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["KONINKLIJKE STERRENWACHT VAN BELGIE", "KONINKLIJKE STERRENWACHT VAN BELGIE"], "EU_Contribution": ["EUR 2 500 000"], "Project_Title": ["Rotation and Nutation of a wobbly Earth"], "Total_Cost": ["EUR 2 500 000"], "Country": ["Belgium", "Belgium"], "Project_ACR": ["RotaNut"], "Technology_Description": "The rotation of the Earth has long been used as a measure of time, and the stars as reference points to determine travellers\u2019 whereabouts on the globe. Today, precise timescales are provided using atomic clocks and precise positioning is determined using geodetic techniques such as GPS grounded on two reference frames: the terrestrial frame, fixed relative to the Earth and rotating synchronously with the planet, and the celestial frame, which is immobile in space, where the artificial satellites such as those of GPS are moving. The relationship between these frames is complicated by the fact that the rotation and orientation of the Earth is subject to irregularities induced by global mass redistributions with time and external forcing such as the gravitational pull of the Sun and the Moon. With the advance of observation precision, the causes of Earth orientation changes are progressively being identified by geodesists and geophysicists. The term \u2018precession\u2019 describes the long-term trend of the orientation of the axis of spin, while \u2018nutation\u2019 is the name given to shorter-term periodic variations, which are the prime focus of the present project. The rotation axis of the Earth is moving in space at the level of 1.5km/year due to precession and has periodic variations at the level of 600 meters as seen from space in a plane tangent to the pole. The present observations allow scientists to measure these at the sub-centimetre level enabling them to identify further physics of the Earth\u2019s interior to be taken into account in the Earth orientation models such as the coupling mechanisms at the boundary between the liquid core and the viscoelastic mantle, as well as many other factors (sometimes not yet definitely identified). The proposed research will address many of these and will result in the development of improved global orientation of the Earth with an unprecedented accuracy - at the sub-centimetre level.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Belgium"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2015-09-01"], "Project_ID": ["670874"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["UNIVERSIDADE NOVA DE LISBOA", "FACULDADE DE CIENCIAS SOCIAIS E HUMANAS DA UNIVERSIDADE NOVA DE LISBOA"], "EU_Contribution": ["EUR 234 448,20"], "Project_Title": ["The Profanation of Opera: Music and Drama on Film"], "Total_Cost": ["EUR 234 448,20"], "Country": ["Portugal", "Portugal"], "Project_ACR": ["PROPERA"], "Technology_Description": "The project PROPERA (The Profanation of Opera: Music and Drama on Film) aims to shed new light on the relationship between opera and film. It draws on the hypothesis that the mediation of film displaces, broadens, and enriches our experience and understanding of opera in ways that have not yet been fully explored in their aesthetic and political potential. To fill this gap, the proposed research on the interplay between the two genres and media over the last hundred years will focus on a variety of objects including not only opera-films, but also feature- and short-length mainstream and experimental movies that incorporate opera in relevant and thought-provoking ways. The ultimate goal of looking at opera through the lens of film is to develop and refine a \u201cprofane\u201d approach to a \u201csacred\u201d genre \u2013 that is, to challenge the identification of opera as a live performance art belonging to an inherently conservative tradition so as to reimagine the past, present, and future of the operatic genre in a media-saturated world. Based on an interdisciplinary approach at the crossroads of opera and film studies, musicology, and philosophy, the consequences of this shift of perspective will be explored from the standpoint of production and spectatorship, with regard to traditional and contemporary repertoire alike. Globally seen, the project \u2013 to be carried out at the University of Chicago and the Universidade Nova de Lisboa, but involving several non-academic institutions \u2013 also seeks to create bridges between scholarly research, artistic practice and public engagement. The outcomes include 1 monograph, at least 6 articles, 3 workshops, 1 international conference, 1 festival, 1 conference series, 1 collaborative on-line platform, and 1 international network on opera, film and new media. If successful, the project will have a considerable impact on the scientific career of the candidate and strongly contribute to the internationalization of the host institution.", "To": ["2020-02-29, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Portugal"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-03-01"], "Project_ID": ["708601"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITY OF HAIFA", "UNIVERSITY OF HAIFA"], "EU_Contribution": ["EUR 1 445 151"], "Project_Title": ["Crisis on the margins of the Byzantine Empire: A bio-archaeological project on resilience and collapse in early Christian development of the Negev Desert"], "Total_Cost": ["EUR 1 445 151"], "Country": ["Israel", "Israel"], "Project_ACR": ["NEGEVBYZ"], "Technology_Description": "This project proposes an innovative, integrative and data-intensive approach to understand the parameters for long-term sustainable functioning of complex societies under vulnerable conditions. The broad aim of the research is to explore contexts of collapse and resilience in an ancient society with high levels of socio-political complexity and technological ingenuity within a resource-limited environment. It focuses on the Byzantine early Christian urban centres of the Negev Desert (4th-7th cent. AD) disclosing both the triumph of human ingenuity in conquering the desert through large-scale human settlement and agricultural development as well as a striking and as yet ambiguous case of wholesale systemic collapse. To test hypotheses regarding social disintegration, economic stress, environmental degradation due to climatic or anthropogenic causes, and the question of plague the project integrates approaches in the archaeology of households, landscapes and garbage through use of biomolecular, botanical, zoological, geological, chronometric, artifactual and contextual sources of data. ", "To": ["2020-08-31, ongoing project |"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["648427"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET", "HELMHOLTZ ZENTRUM POTSDAM DEUTSCHESGEOFORSCHUNGSZENTRUM GFZ", "UNIVERSIDAD DE SALAMANCA", "UNIVERSITY COLLEGE LONDON", "ARCADIS GERMANY GMBH", "ARCADIS DEUTSCHLAND GMBH ADE", "KARLSRUHER INSTITUT FUER TECHNOLOGIE", "AMPHOS 21 CONSULTING SL", "HASKOLI ISLANDS", "NIRAS RADGIVENDE INGENIORER OG PLANLAEGGERE AS", "REGION HOVEDSTADEN", "AECOM URS ESPANA SLU"], "EU_Contribution": ["EUR 3 716 533,44"], "Project_Title": ["Metal oxide Aided Subsurface Remediation: From Invention to Injection"], "Total_Cost": ["EUR 3 716 533,44"], "Country": ["Denmark", "Germany", "Spain", "United Kingdom", "Germany", "Germany", "Germany", "Spain", "Iceland", "Denmark", "Denmark", "Spain"], "Project_ACR": ["METAL-AID"], "Technology_Description": "Thousands of sites across Europe are polluted with toxic metals and organic solvents; many more exist worldwide. As EU population grows, clean water will determine the quality of life and economic stability. Most sites remain contaminated because existing technology is costly and disruptive. Society needs an innovative way to decontaminate soil and groundwater directly underground. In METAL-AID, we will develop new technologies through fundamental knowledge.", "To": ["2020-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-07-01"], "Project_ID": ["675219"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6", "UNIVERSIDADE DA CORUNA", "QUEEN MARY UNIVERSITY OF LONDON", "ASSOCIATION POUR LA RECHERCHE ET LE DEVELOPPEMENT DES METHODES ET PROCESSUS INDUSTRIELS", "STICHTING VU", "THE UNIVERSITY OF EDINBURGH"], "EU_Contribution": ["EUR 2 730 241,94"], "Project_Title": ["Deferred Restructuring of Experience in Autonomous Machines"], "Total_Cost": ["EUR 2 784 240,94"], "Country": ["France", "Spain", "United Kingdom", "France", "Netherlands", "United Kingdom"], "Project_ACR": ["DREAM"], "Technology_Description": "A holy grail in robotics and artificial intelligence is to design a machine that can accumulate adaptations on developmental time scales of months and years. From infancy through adult- hood, such a system must continually consolidate and bootstrap its knowledge, to ensure that the learned knowledge and skills are compositional, and organized into meaningful hierarchies. Consolidation of previous experience and knowledge appears to be one of the main purposes of sleep and dreams for humans, that serve to tidy the brain by removing excess information, to recombine concepts to improve information processing, and to consolidate memory.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["FETPROACT-2-2014 - Knowing, doing, being: cognition beyond problem solving"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-01-01"], "Project_ID": ["640891"], "Call_for_Proposal": ["H2020-FETPROACT-2014"]}, -{"Partners": ["ISTITUTO NAZIONALE DI FISICA NUCLEARE", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "UNIVERSITE BLAISE PASCAL CLERMONT-FERRAND II", "UNIVERSITE CLERMONT AUVERGNE", "UNIVERSITE CATHOLIQUE DE LOUVAIN", "LABORATORIO DE INSTRUMENTACAO E FISICA EXPERIMENTAL DE PARTICULAS", "INSTITUTE OF ACCELERATING SYSTEMS AND APPLICATIONS", "UNIVERSITA DEGLI STUDI DI PADOVA", "EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH", "TECHNISCHE UNIVERSITAET MUENCHEN"], "EU_Contribution": ["EUR 2 402 451,84"], "Project_Title": ["Advanced Multi-Variate Analysis for New Physics Searches at the LHC"], "Total_Cost": ["EUR 2 402 452,42"], "Country": ["Italy", "United Kingdom", "France", "France", "Belgium", "Portugal", "Greece", "Italy", "Switzerland", "Germany"], "Project_ACR": ["AMVA4NewPhysics"], "Technology_Description": "With the 2012 discovery of the Higgs boson at the Large Hadron Collider, LHC, the Standard Model of particle physics has been completed, emerging as a most successful description of matter at the smallest distance scales. But as is always the case, the observation of this particle has also heralded the dawn of a new era in the field: particle physics is now turning to the mysteries posed by the presence of dark matter in the universe, as well as the very existence of the Higgs. The upcoming run of the LHC at 13 TeV will probe possible answers to both issues, providing detailed measurements of the properties of the Higgs and extending significantly the sensitivity to new phenomena. ", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["675440"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON", "UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 139 454"], "Project_Title": ["ExoData: a commercially supported space telescope"], "Total_Cost": ["EUR 139 454"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["ExoData"], "Technology_Description": "ExoData will use results from the very successfull ExoMol Advanced Award which created comprehensive spectroscopic line lists to help understand and model the atmospheres of exoplanets. ExoData will help build and fund a satellite aimed at characterising exoplanet atmospheres using a cheap, agile, low earth orbit satellite mission with a launch date this decade. This mission will be part funded by the sale of telescope data to interested international clients. This is a new business model for astonomical satellites. ExoData will (a) fund business development in partnership with a small company created to sell telescope and other data from this mission and (b) use the results of the ExoMol project to model results from this mission and to create software and models that have potential re-sale value. The deliverable will be funded space mission and a novel business model.", "To": ["2017-04-30, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2015 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-11-01"], "Project_ID": ["693297"], "Call_for_Proposal": ["ERC-2015-PoC"]}, -{"Partners": ["FACULDADE DE CIENCIAS MEDICAS DA UNIVERSIDADE NOVA DE LISBOA", "UNIVERSIDADE NOVA DE LISBOA", "FACULDADE DE CIENCIAS MEDICAS DA UNIVERSIDADE NOVA DE LISBOA", "UNIVERSIDADE NOVA DE LISBOA"], "EU_Contribution": ["EUR 147 500"], "Project_Title": ["Epithelial resistance modulation to treat disease"], "Total_Cost": ["EUR 147 500"], "Country": ["Portugal", "Portugal", "Portugal", "Portugal"], "Project_ACR": ["EMODI"], "Technology_Description": "Epithelial barriers are essential for organism\u2019s homeostasis and survival. Defects in resistance of body barrier epithelial tissues and their repair are thought to underlie a range of diseases, which affect millions. Antonio Jacinto\u2019s group has discovered that Septate/Tight Junctions are essential for epithelial repair. These cell-cell junctions can be potentially targeted by candidate compounds that have been identified by Thelial, a Start-Up that will collaborate in this project. In EMODI we will complete preclinical proof of concept of the potential therapeutic activity of two selected compounds, relying on scientific results and technologies developed under ERC starting grant awarded to Dr. Antonio Jacinto. Regarding clinical application, we will focus on rare (orphan) diseases which have been associated to impaired epithelial repair in the gastro-intestinal track for which there are very limited treatment options: Sjoergen Syndrome (SjS) and Eosinophilic Esophagitis (EoE). The plan of activities involves the following steps: 1) Biological efficacy testing of the-1 and the-2 in a zebrafish Tight Junction model and in mouse models of the diseases under focus; 2) Development of IPR based on the biological testing; 3) Consolidate outcomes of steps 1 and 2 into a business plan; 4) Present the business plan to VC funds to seek for extra round of funding. The long-term aim is clinical development of our candidates not only in the context of SjS and EoE but also towards a range of o diseases where impaired epithelial barrier function is impaired and a cause of morbidity.", "To": ["2018-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2015 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Portugal"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["713735"], "Call_for_Proposal": ["ERC-2015-PoC"]}, -{"Partners": ["HEINRICH-HEINE-UNIVERSITAET DUESSELDORF"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Epidermal growth factor receptor (EGFR) activation by cytohesins - Structural Insights"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["EGFR-Activ"], "Technology_Description": "The epidermal growth factor receptor (EGFR) is a key player in many biological responses and its aberrant function is associated with numerous diseases, including a number of cancers. Despite the significant benefits of anti-EGFR agents in some tumours, many challenges remain in the improvement of EGFR-targeted therapies.", "To": ["2017-05-03, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-05-04"], "Project_ID": ["660258"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 246 668,40"], "Project_Title": ["Fractionalized quantum matter: Characterization, realization and generalization"], "Total_Cost": ["EUR 246 668,40"], "Country": ["France", "United Kingdom"], "Project_ACR": ["Fractional"], "Technology_Description": "With the advent of topological phases, we have recently witnessed a revolution in our understanding of different phases of matter. They are described by tools borrowed from mathematical topology, unlike more familiar phases such as (ferro)magnets, classified in terms of symmetry breaking. Within these topological phases, fractionalized states of matter are of the most exotic, intriguing and potentially useful kind. They result from the delicate interplay between strong correlations among its constituents and the topological nature of the parent non-interacting state. They carry fractional quantum numbers and topologically protected excitations, insensitive to local system details (e.g. impurities) and key to efficient, fault-tolerant quantum computation. The fractional quantum Hall effect (FQHE) is still the hallmark of such phases but it needs strong magnetic fields and low temperatures to be realized, severely constraining the latter groundbreaking scientific leap.", "To": ["2018-11-01, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2015-11-02"], "Project_ID": ["653846"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI PARMA", "SABIC PETROCHEMICALS BV"], "EU_Contribution": ["EUR 513 435,60"], "Project_Title": ["SUPRAmolecular polyolefins as oxygen BARRIER materials"], "Total_Cost": ["EUR 513 435,60"], "Country": ["Italy", "Netherlands"], "Project_ACR": ["SUPRABARRIER"], "Technology_Description": "The production of the next generation of oxygen-barrier polyolefins materials capable of meeting the current and future demands of society in a sustainable manner will require both new technologies and highly trained scientists. Supramolecular chemistry provides a powerful approach to develop new materials with emerging properties, such as low permeability to oxygen, maintaining easy processing. The SUPRABARRIER EID ITN will train a new generation of European scientists with the skills necessary to overcome such future demands and simultaneously develop new strategies for the production of new polymeric systems, which greatly impact important fields such as food and medical packaging. The EID proponents are experts in the areas of supramolecular chemistry and polymer production. Expertise of the partners encompasses the general areas of supramolecular and polymer chemistry, with individual research competencies focusing on a number of specific themes including non-covalent chemistry, supramolecular interactions, polymer blending, polymer processing, polymer production, and Life Cycle Assessment (LCA) analysis and characterisation techniques of complex polymeric and self-assembled materials. The complementarity and diversity realized in synthesis, analysis, development, production and applications is crucial for successful research, innovation and training in this area. The partner from the private sector will extend the fellows\u2019 training beyond that of traditional academic settings, in particular he will have the critical role of bridging fundamental science with application and commercialisation of the results. Our activities will thus possess both breadth and quality that can only be achieved through an interdisciplinary Academy/Industrial European effort.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-EID - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-EID)"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["642929"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["ISTITUTO NAZIONALE DI GEOFISICA E VULCANOLOGIA", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "HELMHOLTZ ZENTRUM POTSDAM DEUTSCHESGEOFORSCHUNGSZENTRUM GFZ", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "UNIVERSITETET I BERGEN", "NATURAL ENVIRONMENT RESEARCH COUNCIL", "KONINKLIJK NEDERLANDS METEOROLOGISCH INSTITUUT-KNMI", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "VEDURSTOFA ISLANDS", "Instytut Geofizyki Polskiej Akademii Nauk", "NATIONAL OBSERVATORY OF ATHENS", "INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA PAMANTULUI", "UNIVERSIDADE DA BEIRA INTERIOR", "GEOFYZIKALNI USTAV AV CR, V.V.I.", "UNIVERSITEIT UTRECHT", "BOGAZICI UNIVERSITESI", "COMMUNICATIONS, CLIMATE ACTION AND ENVIRONMENTS", "KOBENHAVNS UNIVERSITET", "UPPSALA UNIVERSITET", "STICHTING ORFEUS", "HELSINGIN YLIOPISTO", "Euro-Mediterranean Seismological Centre", "BUREAU DE RECHERCHES GEOLOGIQUES ET MINIERES", "CONSIGLIO NAZIONALE DELLE RICERCHE", "KONINKLIJKE STERRENWACHT VAN BELGIE", "OULUN YLIOPISTO", "FOLDMERESI ES TAVERZEKELESI INTEZET", "VYZKUMNY USTAV GEODETICKY TOPOGRAFICKY A KARTOGRAFICKY VVI*RESEARCH INSTITUTE OF GEODESY TOPOGRAPHY AND CARTOGRAPHY VUGTK", "AMRA - ANALISI E MONITORAGGIO DEL RISCHIO AMBIENTALE SCARL", "ARISTOTELIO PANEPISTIMIO THESSALONIKIS", "CENTRO EUROPEO DI FORMAZIONE E RICERCA IN INGEGNERIA SISMICA", "Geological Survey of Denmark and Greenland", "OBSERVATORIO DEL EBRO FUNDACION", "INSTITUT NATIONAL DE L ENVIRONNEMENT ET DES RISQUES INERIS", "UNIVERSITA DEGLI STUDI ROMA TRE", "ETHNIKO KENTRO VIOSIMIS KAI AEIFOROU ANAPTYXIS", "LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN", "LULEA TEKNISKA UNIVERSITET", "ZNANSTVENORAZISKOVALNI CENTER SLOVENSKE AKADEMIJE ZNANOSTI IN UMETNOSTI", "Istituto Superiore per la Protezione e la Ricerca Ambientale", "THE UNIVERSITY OF LIVERPOOL", "UNIVERSITY OF KEELE", "ILMATIETEEN LAITOS", "AKADEMIA GORNICZO-HUTNICZA IM. STANISLAWA STASZICA W KRAKOWIE", "UNIVERSITY OF LEEDS", "BASBAKANLIK AFET VE ACIL DURUM YONETIMI BASKANLIGI", "INSTITOUTO GEOLOGIKON KAI METALLEFTIKON EREVNON", "TRUST-IT SERVICES LIMITED"], "EU_Contribution": ["EUR 18 374 344"], "Project_Title": ["EPOS Implementation Phase"], "Total_Cost": ["EUR 31 030 832,46"], "Country": ["Italy", "France", "Germany", "Switzerland", "Norway", "United Kingdom", "Netherlands", "Spain", "Iceland", "Poland", "Greece", "Romania", "Portugal", "Czech Republic", "Netherlands", "Turkey", "Ireland", "Denmark", "Sweden", "Netherlands", "Finland", "France", "France", "Italy", "Belgium", "Finland", "Hungary", "Czech Republic", "Italy", "Greece", "Italy", "Denmark", "Spain", "France", "Italy", "Greece", "Germany", "Sweden", "Slovenia", "Italy", "United Kingdom", "United Kingdom", "Finland", "Poland", "United Kingdom", "Turkey", "Greece", "United Kingdom"], "Project_ACR": ["EPOS IP"], "Technology_Description": "The nations of Europe are distributed around some of the most complex and dynamic geological systems on the planet and understanding these is essential to the security of livelihoods and economic power of Europeans. Many of the solutions to the grand challenges in the geosciences have been led by European scientists \u2013 the understanding of stratigraphy (the timing and distribution of layers of sediment on Earth) and the discovery of the concept of plate tectonics being among the most significant. Our ability to monitor the Earth is rapidly evolving through development of new sensor technology, both on- and below-ground and from outer space; we are able to deliver this information with increasing rapidity, integrate it, provide solutions to geological understanding and furnish essential information for decision makers. ", "To": ["2019-09-30, ongoing project |"], "Meta": [""], "Topic_s": ["INFRADEV-3-2015 - Individual implementation and operation of ESFRI projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Other", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-10-01"], "Project_ID": ["676564"], "Call_for_Proposal": ["H2020-INFRADEV-1-2015-1"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM", "UNIVERSITAET LEIPZIG", "STIFTUNG DEUTSCHE GEISTESWISSENSCHAFTLICHE INSTITUTE IM AUSLAND - DGIA", "UNIVERSITE DE ROUEN NORMANDIE", "LATVIJAS UNIVERSITATE", "UNIWERSYTET SLASKI", "KLAIPEDOS UNIVERSITETAS", "UNIVERSITATSMEDIZIN GREIFSWALD KORPERSCHAFT DES OFFENTLICHEN RECHTS", "UNIVERZITA JANA EVANGELISTY PURKYNE V USTI NAD LABEM", "LUDWIG BOLTZMANN GESELLSCHAFT OSTERREICHISCHE VEREINIGUNG ZUR FORDERUNG DER WISSENSCHAFTLICHEN FORSCHUNG", "STICHTING REINIER VAN ARKEL", "UNIVERSITAET AUGSBURG"], "EU_Contribution": ["EUR 3 729 290,40"], "Project_Title": ["Children Born of War - Past, Present and Future"], "Total_Cost": ["EUR 3 729 290,65"], "Country": ["United Kingdom", "Germany", "Germany", "France", "Latvia", "Poland", "Lithuania", "Germany", "Czech Republic", "Austria", "Netherlands", "Germany"], "Project_ACR": ["CHIBOW"], "Technology_Description": "The physical and psychosocial impact of armed conflict on children is immense and particularly so, if these children are associated with the enemy. Overwhelming evidence suggests that children born of war (CBOW), i.e. children fathered by foreign soldiers and born to local mothers have been and continue to be a major obstacle to successful integration of both their mothers and themselves into post-conflict societies. At a global level, previous UN studies have further emphasized the lack of research on children born out of forced pregnancies in armed conflict. The proposed network addresses the described shortcomings by advancing the knowledge base through systematic analysis of lived experiences of CBOW in a variety of 20th century conflict and post-conflict situations. ", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Other", "Higher or Secondary Education Establishments"], "From": ["2015-03-01"], "Project_ID": ["642571"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["THE SCOTTISH ASSOCIATION FOR MARINESCIENCE LBG", "FRIEDRICH-SCHILLER-UNIVERSITAT JENA", "UNIVERSITAT KONSTANZ", "OSTRAVSKA UNIVERZITA", "A4F ALGAFUEL SA", "VIB", "UNIVERSITEIT GENT", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "PROVIRON HOLDING NV", "APPLIED MATHS NV"], "EU_Contribution": ["EUR 3 794 115,24"], "Project_Title": ["The Algal Microbiome: Friends and Foes"], "Total_Cost": ["EUR 3 794 115,24"], "Country": ["United Kingdom", "Germany", "Germany", "Czech Republic", "Portugal", "Belgium", "Belgium", "France", "Belgium", "Belgium"], "Project_ACR": ["ALFF"], "Technology_Description": "Algal aquaculture is developing exponentially worldwide, with multiple applications in the food, chemical and pharmaceutical industries. Current research in algal biotechnology mostly focuses on metabolite discovery, aquaculture yield improvement and engineering bottlenecks. However, agronomical experience shows that controlling the interaction of land crops with mutualistic or pathogenic microbes is most critical to successful production. Likewise, controlling the microbial flora associated with algae (the 'algal microbiome') is emerging as the biggest biological challenge for their increased usage. Bacteria can control the morphogenesis of algae, while others are indispensable to algal survival. Pathogens are causing devastating diseases, the impact of which worsens with the intensification of aquaculture practices. Thus, the overarching aim of ALFF is to train 15 ESRs (researchers and technologists) within a multinational consortium, whilst bringing a scientific step-change in our understanding of these interactions, leading to the development of superior mass algal cultivation and biocontrol strategies. ALFF tackles: 1) the identification, taxonomy and utilisation of naturally-occurring algal symbionts and pathogens; 2) inter- and intra-species signalling and chemical ecology in aquaculture, natural environment and simplified systems (i.e. axenic cultures +/- symbionts); 3) and harnesses state of the art genomics, molecular, and biochemical techniques to characterise these interactions. A highly interdisciplinary team underpins an ambitious theoretical, field, hands-on training and research program. With the support of high profile institutions, ALFF foresees an exceptionally broad range of dissemination and outreach initiatives to help policy makers and the general public better understand the opportunities and issues relating to the sustainable use of our aquatic freshwater and marine resources, within and beyond the EU.", "To": ["2018-12-31, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["642575"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["UNIVERSITEIT UTRECHT"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["Shifting political power: the nature and consequences of distributed renewable energy transitions"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["POWERSHIFTS"], "Technology_Description": "Global energy transitions are progressing rapidly. Over half of new generation capacity in 2014 came from renewable energy. Individual, community and co-operative decentralized renewable energy (DRE) producers are capturing a growing share of energy markets (e.g. solar, wind, biomass). As their market share increases, DRE producers are becoming increasingly effective political actors. The traditional political privilege enjoyed by incumbent industries is challenged by these DRE actors as they shift control over jobs, economic growth and energy supplies. Political struggles between competing interests are increasing. However, the nature and extent of these power shifts (e.g. changes in access to policy makers, media influence), and their consequences for political systems and their outcomes (e.g. contested carbon targets, renewable energy subsidies) are poorly understood. This project addresses how and why DRE transitions are shifting political power relations, and the consequences of those shifts for political systems and outcomes. Using an interdisciplinary approach grounded in theory on sustainability transitions (i.e. Multi-Level Perspective), power (e.g. Lukes, Foucault) and institutions (i.e. institutional logics) the project will: (1) examine the conditions leading to shifts in political power by analyzing existing political power relations in regimes where DRE transitions are expected, occurring, or stalled; (2) assess the mechanisms by which political power shifts resulting from these DRE transitions are occurring; and, (3) identify the consequences of DRE-related political power shifts for political systems and their outcomes. Objectives will be explored using a global survey of 20 DRE regimes. Survey insights will be expanded in 5 international comparative cases. Findings will address urgent questions highlighted by academics, the EU, and global economic bodies about the political, economic and social impacts of the changing energy landscape.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["751843"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Central Authority and Local Strenght in Early Middle Ages: Comparing social complexity in Northern Iberia and Central Italy (8th \u2013 10th centuries)"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["CALOSEMA"], "Technology_Description": "Intending the Early Middle Ages as one of the most astonishing political and social laboratories in Europe\u2019s history, the main goal of \u201cCALOSEMA\u201d project is the study of social complexity between the 8th and 10th centuries, comparing societies and political landscapes from two European macro-regions: Northern Iberia and Central Italy, in order to (a) to investigate social, economic and political complexities on a continental scale, with the main intention of interpreting \u201clandscapes of social and political inequality\u201d going beyond the contraposition between History and Archaeology; (b) to create a social theory which would allow the insertion of medieval examples in the existing historiographical debates and, finally, (c) to deepen the concepts social and political inequality in the historical evolution of societies and powers which must be always considered as processes in progress, (d) to deconstruct historiographical rhetorics about the birth of different nations and states in Europe (and the origin of Europe itself) in the Early Middle Ages.", "To": ["2019-09-24, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-25"], "Project_ID": ["748161"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF KEELE"], "EU_Contribution": ["EUR 251 857,80"], "Project_Title": ["Motivation\u2013cognition interaction in healthy ageing and Parkinson\u2019s disease"], "Total_Cost": ["EUR 251 857,80"], "Country": ["United Kingdom"], "Project_ACR": ["Motivageing"], "Technology_Description": "Europe is greying. This has enormous economic and social costs for the entire society, through greater numbers of healthy older adults with cognitive decline, and of people with neurodegenerative disorders that can lead to dementia, such as Parkinson\u2019s disease (PD). MOTIVAGEING aims to address this issue by proposing a new approach for the enhancement of working memory (WM) capacity, in order to improve cognitive function, quality of life and wellbeing of healthy older adults and PD patients. In fact, there is no current effective treatment for age-related WM decline or WM deficits and related behavioural and affective problems in PD patients. Based on a promising new theory of cognitive neuroscience, the Motivation-Cognition Interaction (MoCoInt) framework, the present plan employs an interdisciplinary approach: in Study 1, an innovative multimodal functional neuroimaging method is proposed to analyse for the first time the neural mechanisms of MoCoInt in healthy ageing. The new evidence will provide a foundation for Study 2, in which the efficacy of a novel WM training procedure, based on MoCoInt, will be tested in healthy older adults in order to improve their WM capacity. Finally, to understand if this new training procedure can be employed to treat WM deficits in PD, Study 3 investigates for the first time MoCoInt mechanisms in PD patients in relation to pharmacological treatment, through the conduct of a randomised controlled drug trial. Results will enable to extend MoCoInt to healthy and pathological ageing, and to develop a new framework that will be available as a new theoretical model for both researchers and clinicians. MOTIVAGEING will therefore have both a significant scientific multidisciplinary impact, filling several gaps in knowledge in cognitive neuroscience, cognitive and clinical neuropsychology, and a valuable social and economic impact in the European Union, helping to address the crucial issues posed by the ageing population.", "To": ["2021-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["749084"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Elucidating novel post-transcriptional regulatory mechanisms in neural development"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["Brain_stability"], "Technology_Description": "During brain development, neural stem cells (neuroblasts) divide asymmetrically to produce a neuroblast and a neural progenitor cell, the ganglion mother cell (GMC), which will later divide to produce two neurons or glia. Asymmetric protein localization and transcriptional activation are two well-established mechanisms that influence cell fate decisions during this process. I hypothesize that a relatively unexplored regulatory component\u2014mRNA stability\u2014also plays a major role in neural differentiation. mRNA stability is regulated to achieve high temporal and spatial control of gene expression and may therefore provide a powerful way to establish or reinforce cell fate decisions in the nervous system. However, little is known about the functions of regulated mRNA stabilization or decay during development of the brain (or any other complex tissue). Our lab recently discovered that the mRNA encoding a key conserved neural differentiation-promoting transcription factor, Prospero, is unstable in Drosophila neuroblasts, but is stabilized in the more differentiated GMCs. This proposal seeks to expand upon this finding and to determine the extent of mRNA stability regulation and its functional significance in the developing brain. I aim to develop a novel genome-wide technique that will allow quantitative comparison of mRNA decay rates between neuroblasts and GMCs. I will then use this technique to query the function of conserved RNA-binding proteins in the regulation of neural mRNA stability. Finally, I will use our state-of-the-art live brain imaging assays to determine the functional requirement for specific regulatory events in brain development at the cellular and molecular levels. The experiments described in this proposal have the potential to uncover a major new class of post-transcriptional regulatory events that determine the balance between proliferation and differentiation in the developing brain.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["750928"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Learning under Conflict: Effects of political violence on the educational attainment of Palestinian students in the West Bank"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["CSPIWB"], "Technology_Description": "This project aims to examine the causal effect of the Israeli-Palestinian conflict on the achievements of Palestinian high school students in their final exams that conclude the high school degree between the years 1998-2012, and the mechanism behind it. The analysis in the project will rely on a unique data source, which will ensure a relatively clean identification of the effects of conflict on Palestinian students' achievements. Data on students' achievements and schools include unique data on the individual test scores in all subjects at the Palestinian high school final exam (the Tawjihi General Examination) for the whole population of Palestinian students enrolled in their final year of the Arts and the Scientific curricula, and information on the characteristics of all high schools in the West Bank, including unique data on the teachers. The custom-made data on political violence will be comprised of datasets stemming from different sources. The first source is Geographic Information System (GIS) data on various types of conflict-induced restrictions to mobility, including check-points, and roadblocks, within the West Bank, which enable a calculation of the gap of distance and time between individual\u2019s locality of residence and locality of school, with and without the presence of Israeli physical barriers to movement. The second source is conflict-related Palestinian fatalities and prisoners. ", "To": ["2019-07-04, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-05"], "Project_ID": ["752410"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH"], "EU_Contribution": ["EUR 175 419,60"], "Project_Title": ["Higher-loop amplitudes on the sphere: a new approach to the perturbative expansion of quantum field theories"], "Total_Cost": ["EUR 175 419,60"], "Country": ["Switzerland"], "Project_ACR": ["NewLoops"], "Technology_Description": "Almost all we know about particle physics and the Standard Model comes from scattering experiments and our ability to predict them via scattering amplitudes (these measure probabilities of scattering processes). To meet the impressive technological advances of particle colliders like the Large Hadron Collider at CERN, new tools and concepts have emerged over the last 25 years. More than giving methods, they have triggered a revolution in our understanding of the formal microscopic structure of particle physics, a subject people thought they knew everything about.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Research Organisations"], "From": ["2017-10-01"], "Project_ID": ["749793"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FACULDADE DE CIENCIAS MEDICAS DA UNIVERSIDADE NOVA DE LISBOA", "UNIVERSIDADE NOVA DE LISBOA"], "EU_Contribution": ["EUR 160 635,60"], "Project_Title": ["A genetic model for neurorehabilitation"], "Total_Cost": ["EUR 160 635,60"], "Country": ["Portugal", "Portugal"], "Project_ACR": ["GEMiNI"], "Technology_Description": "Coordinated walking in vertebrates and multi-legged invertebrates such as the fruit fly Drosophila melanogaster is controlled by an evolutionarily conserved network capable to control movement in a fast, stable, and energy-efficient way. At the same time, it provides the flexibility to adapt to changes in the terrain, load, and internal motor representations due to disease or injury. Currently, the contribution of different brain structures responsible for the recovery process is only partially understood and, importantly, the role of specific genes remains mostly elusive. Preliminary data shows that adult Drosophila flies in which the two middle legs were amputated improve their gait performance gradually over the course of a few days engaging in a more controlled gait. We also find that mutants for the learning and memory gene rutabaga lack any kind of short- or long-term recovery. These results suggest that flies can readjust their motor circuitry upon injury and that a mechanism of synaptic plasticity might be involved.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Portugal"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["752891"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF LEEDS", "ACADEMISCH ZIEKENHUIS LEIDEN", "KING'S COLLEGE LONDON", "FACULTY OF SCIENCE UNIVERSITY OF ZAGREB", "THE UNIVERSITY OF EDINBURGH", "GLYXERA GMBH", "GENOS DOO ZA VJESTACENJE I ANALIZU", "ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA"], "EU_Contribution": ["EUR 2 864 761,20"], "Project_Title": ["Innovative training in methods for future data"], "Total_Cost": ["EUR 2 864 761,20"], "Country": ["United Kingdom", "Netherlands", "United Kingdom", "Croatia", "United Kingdom", "Germany", "Croatia", "Italy"], "Project_ACR": ["IMforFUTURE"], "Technology_Description": "IMforFUTURE is an innovative multidisciplinary and intersectoral research training programme which addresses current shortcomings in omics research. We aim to open the new research horizon in integration of genetics, glycomics, and epigenomics datasets into systems biology by developing innovative methods for high throughput omics and for integrative analysis of omics data. We focus on ageing, which is the biggest single risk factor for many diseases. By application of our novel methods to emerging datasets representing inflammation and immunology, IMforFUTURE will contribute to understanding of the underlying biological processes involved in diseases and ageing.", "To": ["2021-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["721815"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["UNIVERSITEIT LEIDEN"], "EU_Contribution": ["EUR 197 725,50"], "Project_Title": ["Women at the Cutting Edge. Assessing the gendered impact of industrial logging on well-being in Solomon Islands."], "Total_Cost": ["EUR 197 725,50"], "Country": ["Netherlands"], "Project_ACR": ["WACE"], "Technology_Description": "Women are often negatively affected by industrial logging in tropical forests. They are excluded from decision-making, and are vulnerable to the sexual exploitation, alcoholism and conflict associated with this extractive industry. However, the scientific literature on the impacts of logging on women\u2019s well-being is fragmented, and the subject receives little attention from policy and industry. This project aims to address this gap by: 1) publishing 3 peer-reviewed articles in high-impact, open-access journals on the gendered impacts of logging in Solomon Islands, based on an innovative combination of ethnographic and quantitative research methods; 2) compiling case studies on women in logging concessions in a special issue of the journal of the European Tropical Forest Research Network; 3) developing a methodological toolkit for the systematic assessment of women\u2019s well-being in forest concessions. The project results will be further communicated to professional and lay-audiences through oral presentations, policy briefs, newsletters, a website and on-line articles.", "To": ["2019-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["748242"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["DEUTSCHES ZENTRUM FUR NEURODEGENERATIVE ERKRANKUNGEN EV"], "EU_Contribution": ["EUR 239 860,80"], "Project_Title": ["Assessment of Reserve: Translational Evaluation of Medical Images and Statistics-Prediction models for outcomes of brain health"], "Total_Cost": ["EUR 239 860,80"], "Country": ["Germany"], "Project_ACR": ["ARTEMIS"], "Technology_Description": "Stroke and cognitive decline are among the leading contributors to disease burden and long-term disability worldwide. Despite their prevalence, the contributing disease processes are not fully understood. This is in part due to the lack of (early) prediction models and ways to characterize protective mechanisms, which can help to distinguish between patients and healthy individuals before symptoms manifest. Such prediction models can facilitate prevention strategies for adverse cognitive and functional outcomes, thereby enriching patients\u2019 life quality and reduce the economic burden on society. Advanced neuroimaging techniques, such as MRI, have provided additional insight into the underlying disease biology. One major challenge when using neuroimaging techniques lies in the fact that large amounts of data are required to account for variations in clinical presentation and assessment, necessitating the use of dedicated pipelines for extracting phenotypes. However, most pipelines are developed in research settings and tend to fail when applied to real-life clinical cohorts, leading to a subpar use of rich, available patient datasets.", "To": ["2020-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations"], "From": ["2017-04-01"], "Project_ID": ["753896"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITEIT ANTWERPEN"], "EU_Contribution": ["EUR 160 800"], "Project_Title": ["Anticancer activity of plasma activated medium and its underlying mechanisms: Combined experimental and computational study"], "Total_Cost": ["EUR 160 800"], "Country": ["Belgium"], "Project_ACR": ["Anticancer-PAM"], "Technology_Description": "Cold atmospheric plasma (CAP) is gaining increasing interest for cancer treatment, although the application is still in its early stages. Besides direct CAP treatment of cancer cells, plasma can also be used to activate a liquid medium, which seems to have similar anti-cancer effects as the plasma itself. This so-called plasma activated medium (PAM) is very promising for cancer treatment, as it can be more generally used, e.g., it might be directly injected into tissue of patients. However, the anticancer potential of PAM is not yet fully understood. This is exactly the focus of this project. We will measure the reactive oxygen and nitrogen species (RONS) concentrations in PAM, and also calculate them with a model for plasma-liquid interaction. In addition, we will study the effect of PAM on a catalase model protein by experiments, and perform atomic scale simulations for the interaction of RONS with this protein, to better understand the effect of PAM on cancer cells, because catalase aids cancer cells in overcoming oxidative stress created by PAM.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["743546"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAET SIEGEN"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Development of photoswitchable ligands for the reversible and selective assembly with RNA"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["PHOTORNA"], "Technology_Description": "The proposed project aims at the development of novel functional ligands whose association with ribonucleic acid (RNA) is reversibly activated by light. As several RNA forms are essential key elements in physiological processes, the control of their function or malfunction by the reversible binding of photoswitchable ligands possesses a great potential as a tool in anticancer, antiviral and antimicrobial therapy. Surprisingly, this innovative approach towards a controlled reversible generation of RNA binders was mainly neglected in this highly topical research field. Hence, in this project photochromic hemi-indigo and fulgide derivatives are chosen as a platform for the design of photo-responsive RNA ligands, because i) they exhibit general features of RNA binders; ii) their structure can be reversibly modified by light, iii) the core structures are readily synthesized, and iii) the substitution pattern can be easily varied to enable fine-tuning of binding selectivity based on structure-activity relationships. In addition, conjugates that comprise two photoactive RNA-binding units will be obtained and studied because such bifunctional binders are expected to have very high affinity and selectivity toward RNA. An extensive library of derivatives will be synthesized and tested for their photocontrollable association with RNA. As a special method, real-time NMR-spectroscopic studies with direct irradiation of the sample inside a specifically designed spectrometer will be used to assess in detail the dynamics in the course of the photoinduced ligand\u2013RNA interactions. Overall, it is anticipated that this systematic approach will enable the identification and development of lead structures for controllable RNA-targeting drugs with a great pharmacological potential. Moreover, the high interdisciplinary, innovative character of this challenging project gives the researcher an excellent opportunity to achieve professional maturity and open up best career possibilities.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["749788"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSIDAD POMPEU FABRA"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["The Role of the Ethnic Majority in Integration Processes: Attitudes and Practices towards Immigrants in Catalan Institutions"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["REPCAT"], "Technology_Description": "This project proposal aims to take research on diversity management and integration further by focusing on how ethnic diversity is represented in three central Catalan institutions: the public school system, the Catalan police force and the City council of Barcelona. The case of Catalonia appears particularly relevant for an empirical study on the actual representation of diversity given its pronounced intercultural policy focus, while socio-economic inequality between natives and immigrants is vast, and many immigrants live in situations of precariousness and marginalization. ", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["747075"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF NOTTINGHAM", "INSTITUT FRANCAIS DES SCIENCES ET TECHNOLOGIES DES TRANSPORTS, DE L'AMENAGEMENT ET DES RESEAUX", "UNIVERSITA DEGLI STUDI DI PALERMO", "UNIVERSIDAD DE GRANADA", "POLITECNICO DI MILANO", "EIFFAGE INFRASTRUCTURES GESTION ET DEVELOPPEMENT", "AECOM INFRASTRUCTURE & ENVIRONMENT UK LIMITED", "GAVIN AND DOHERTY GEOSOLUTIONS LTD", "DYNATEST INTERNATIONAL AS"], "EU_Contribution": ["EUR 3 990 940,92"], "Project_Title": ["European Training Network on Sustainable Multi-functional Automated Resilient Transport Infrastructures."], "Total_Cost": ["EUR 3 990 940,92"], "Country": ["United Kingdom", "France", "Italy", "Spain", "Italy", "France", "United Kingdom", "Ireland", "Denmark"], "Project_ACR": ["SMARTI ETN"], "Technology_Description": "Sustainable Multi-functional Automated Resilient Transport Infrastructures ETN, will bring together a stimulating platform where the stakeholders of the transport infrastructure sector will work alongside world-wide experts in smartening of systems (developers of high-tech sensors, advanced monitoring equipment, automated structures, etc.,) with direct support from the roads, railways and airports managers. This environment will enable talented graduates to conceive the transport infrastructure network of the future and will provide them with world-wide extended training in each of the four pillars supporting the SMARTI vision: designed to last by maximising recycling and minimizing impact (Sustainable), conceived not for transport purposes only and towards optimisation of land use (Multi-functional), equipped for communicating with managers and users, to allow a more intuitive use and a simplified management (Automated), built to be adaptable to natural and anthropogenic hazards (Resilient). The consortium will combine and share expertise to offer advanced scientific training structured into network-wide thematic taught modules combined with original research supported by secondments that will expose fellows to both academia and industry and will also allow them with the possibility to be award with Doctoratus Europeus. The training programme will be enriched by specific modules to support job creation by enabling the fellows with business, entrepreneurship, communication, project management and other transferrable skills. A tailored Dissemination strategy will evaluate the variety of channels and means appropriate to allow the fellows to be prepared and successful in reaching both scientific and larger public audiences. As a result, SMARTI ETN will create a new generation of highly-skilled and appealing professionals that will be in great demand in this rapidly expanding field and will benefit Europe and developing countries.", "To": ["2021-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-03-01"], "Project_ID": ["721493"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["UNIWERSYTET ROLNICZY IM. HUGONA KOLLATAJA W KRAKOWIE", "KOBENHAVNS UNIVERSITET", "THE UNIVERSITY OF NOTTINGHAM", "UNIVERSITEIT GENT", "TECHNISCHE UNIVERSITAET BERLIN", "KATHOLIEKE UNIVERSITEIT LEUVEN"], "EU_Contribution": ["EUR 2 078 485,56"], "Project_Title": ["Food science, technology and engineering - European Joint Doctorate training towardsknowledge, skills and mobility"], "Total_Cost": ["EUR 2 078 485,56"], "Country": ["Poland", "Denmark", "United Kingdom", "Belgium", "Germany", "Belgium"], "Project_ACR": ["EJDFoodSci"], "Technology_Description": "The objective of the proposal is to train 8 early stage researches (ESR) in an innovative, international PhD program, to become top-class specialists and professional leaders, highly demanded in the job market, ready to introduce innovations and manage advanced research. The completion of the training programme will provide ESRs with appropriate knowledge, skills and awareness of the science-business reality, crucial for scientific and/or commercial based research projects.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EJD - European Joint Doctorates"], "Coordinated_in": ["Poland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["722166"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["TECHNISCHE UNIVERSITAET MUENCHEN"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Direct Pathway Cloning of Neglected Bacteria in the Hunt for Novel (Bio-)Chemistry"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["DiPaC_MC"], "Technology_Description": "To overcome recent global health threats, such as antibiotic resistance, a resurgence in the discovery of new chemical and thus biomedical diversity from microbial sources is needed. Genome mining in combination with heterologous expression is an approach that will overcome these challenges. It involves incorporation of yet uncharacterized natural product genetic loci into a fast growing heterologous host. For this approach, a prolific source of novel natural product gene clusters is vital. Our collaboration with the Zentralinstitut f\u00fcr Ern\u00e4hrungs- und Lebensmittelforschung (ZIEL, Technische Universit\u00e4t M\u00fcnchen) provides direct access to bacterial isolates completely unexplored in regards to their potential for natural product biosynthesis. Our genome analyses have revealed that many of the ZIEL isolates harbor a large number of uncharacterized natural product gene clusters. Thus, the aim of this proposal is to heterologously express natural product gene clusters from these neglected bacteria to discover novel natural product (bio-)chemistry. Because these organisms are poorly studied, the likelihood of discovering rare or novel biochemistry is immensely increased. Here, we will utilise a novel combination of synthetic biology techniques referred to as Direct Pathway Cloning. This will enable expression vectors to be constructed by large-amplicon PCR (up to 20kb) coupled to Gibson assembly. Development of the methodology is set to revolutionise synthetic biology and metabolic engineering. Downstream outcomes of this proposal will be the identification of novel, potentially bioactive natural products, the characterisation of unusual biochemistry and the addition of enzymes to the \u2018biocatalytic toolkit\u2019 for natural product synthesis and structural alteration.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["745435"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ECOLE NORMALE SUPERIEURE DE LYON", "ECOLE NORMALE SUPERIEURE DE LYON", "FONDATION POUR L'UNIVERSITE DE LYON"], "EU_Contribution": ["EUR 2 496 242,50"], "Project_Title": ["Silver Isotopes and the Rise of Money"], "Total_Cost": ["EUR 2 496 242,50"], "Country": ["France", "France", "France"], "Project_ACR": ["SILVER"], "Technology_Description": "Silver was the primary metal of economic exchange and military finances in ancient Mediterranean and Near-Eastern societies. Silver isotopes will help quantify monetization of these societies by identifying Ag mineral sources, monetary sinks, and its major transfer routes. High-precision stable Ag isotope analysis initiated in Lyon has shed new light on the provenance of silver coinage. This is because Ag isotopes are distinctive of coinage\u2019s intrinsic value in contrast to traditionally-used Pb and Cu isotopes, which may characterize impurities or additives. ", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other"], "From": ["2017-10-01"], "Project_ID": ["741454"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM", "THE UNIVERSITY OF BIRMINGHAM"], "EU_Contribution": ["EUR 1 790 580"], "Project_Title": ["A Comparative Study of Resilience in Survivors of War Rape and Sexual Violence: New Directions for Transitional Justice"], "Total_Cost": ["EUR 1 790 580"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["CSRS"], "Technology_Description": "The profound trauma associated with rape and sexual violence in conflict has been extensively explored within existing scholarship. The fact that many survivors exhibit remarkable post-trauma resilience, however, remains critically under-investigated. CSRS will address this fundamental gap by undertaking a paradigm-shifting empirical study of the underlying conditions for resilience. It will then use this data to pioneer a new, survivor-centred model of transitional justice \u2013 the process of redressing the legacy of massive human rights abuses. ", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["724518"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN", "OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN"], "EU_Contribution": ["EUR 2 496 525"], "Project_Title": ["Simulating 2d Spin Lattices with Ion Crystals"], "Total_Cost": ["EUR 2 496 525"], "Country": ["Austria", "Austria"], "Project_ACR": ["SPICY"], "Technology_Description": "The objective of this project is to experimentally realize a 100-particle quantum simulator with complete quantum control at the single-particle level that will be used for investigating models of interacting spins in two dimensions. ", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Austria"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["741541"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["STICHTING VU", "STICHTING VU"], "EU_Contribution": ["EUR 2 499 714"], "Project_Title": ["Becoming A Minority"], "Total_Cost": ["EUR 2 499 714"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["BAM"], "Technology_Description": "In the last forty years, researchers in the Field of Migration and Ethnic Studies looked at the integration of migrants and their descendants. Concepts, methodological tools and theoretical frameworks have been developed to measure and predict integration outcomes both across different ethnic groups and in comparison with people of native descent. But are we also looking into the actual integration of the receiving group of native \u2018white\u2019 descent in city contexts where they have become a numerical minority themselves? In cities like Amsterdam, now only one in three youngsters under age fifteen is of native descent. This situation, referred to as a majority-minority context, is a new phenomenon in Western Europe and it presents itself as one of the most important societal and psychological transformations of our time. I argue that the field of migration and ethnic studies is stagnating because of the one-sided focus on migrants and their children. This is even more urgent given the increased ant-immigrant vote. These pressing scientific and societal reasons pushed me to develop the project BAM (Becoming A Minority). The project will be executed in three harbor cities, Rotterdam, Antwerp and Malm\u00f6, and three service sector cities, Amsterdam, Frankfurt and Vienna. BAM consists of 5 subprojects: (1) A meta-analysis of secondary data on people of native \u2018white\u2019 descent in the six research sites; (2) A newly developed survey for the target group; (3) An analysis of critical circumstances of encounter that trigger either positive or rather negative responses to increased ethnic diversity (4) Experimental diversity labs to test under which circumstances people will change their attitudes or their actions towards increased ethnic diversity; (5) The formulation of a new theory of integration that includes the changed position of the group of native \u2018white\u2019 descent as an important actor.", "To": ["2022-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["741532"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["TECHNISCHE UNIVERSITAET WIEN", "TECHNISCHE UNIVERSITAET WIEN"], "EU_Contribution": ["EUR 1 513 335,34"], "Project_Title": ["X-ray-waveforms at the Space-Time Resolution Extreme for Atomic-scale Movies"], "Total_Cost": ["EUR 1 513 335,34"], "Country": ["Austria", "Austria"], "Project_ACR": ["XSTREAM"], "Technology_Description": "Nonlinear optics revolutionized the ability to create directed, coherent beams particularly in spectral regions where lasers based on conventional population inversion are not practical. New breakthroughs in extreme nonlinear optics promise a similar revolution in the X-ray regime. In a dramatic and unanticipated breakthrough, an international team lead by the PI demonstrated that the high harmonic generation process (HHG) driven by mid-IR lasers can be used to generate keV photons, implementing a >5000 order nonlinear process, while still maintaining the full phase matching that is necessary for good conversion efficiency. This work represents the most extreme, fully coherent upconversion for electromagnetic waves in the 50 year history of nonlinear optics. Moreover, the limits of HHG are still not understood, either theoretically or experimentally. It may be possible to generate coherent hard X-rays using a tabletop-scale apparatus.", "To": ["2022-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["716950"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["UNIVERSITEIT LEIDEN", "UNIVERSITEIT LEIDEN"], "EU_Contribution": ["EUR 2 498 296"], "Project_Title": ["Open Philology: The Composition of Buddhist Scriptures"], "Total_Cost": ["EUR 2 498 296"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["OpenPhilology"], "Technology_Description": "Buddhist s\u016btras are fundamental sources for understanding the beliefs that once dominated, and largely continue to dominate, Asian societies. But classical philological approaches to these texts, assuming an Ur-text and linear development, misrepresent their nature and obscure their history. Like oral literature the s\u016btras are authorless and textually fluid, their content formulaic and modular, and the situation complicated by their huge volume and the linguistic diversity of their extant versions. Their fluidity and the absence of an Ur-text makes traditional stemmatic editing inappropriate. Other options are also unacceptable: eclectic editions conflate distinct sources, creating texts which never existed historically, while exclusive focus on a single version ignores the tradition\u2019s true richness. ", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["741884"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITAET LEIPZIG", "UNIVERSITAET LEIPZIG"], "EU_Contribution": ["EUR 1 860 875"], "Project_Title": ["Differential Inclusions and Fluid Mechanics"], "Total_Cost": ["EUR 1 860 875"], "Country": ["Germany", "Germany"], "Project_ACR": ["DIFFINCL"], "Technology_Description": "Important problems in science often involve structures on several distinct length scales. Two typical examples are fine phase mixtures in solid-solid phase transitions and the complex mixing patterns in turbulent or multiphase flows. The microstructures in such situations influence in a crucial way the macroscopic behavior of the system, and understanding the formation, interaction and overall effect of these structures is a great scientific challenge. Although there is a large variety of models and descriptions for such phenomena, a recurring issue in the mathematical analysis is that one has to deal with very complex and highly non-smooth structures in solutions of the associated partial differential equations. ", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["724298"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE", "LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE"], "EU_Contribution": ["EUR 1 499 094"], "Project_Title": ["Investigating the predictors of intimate partner violence: a mixed method longitudinal study in Tanzania"], "Total_Cost": ["EUR 1 499 094"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["IPV_Tanzania"], "Technology_Description": "This study proposes a major advance in research on intimate partner violence (IPV), a prominent public health and human rights issue. Worldwide, it is estimated that one in three women experience physical and/or sexual violence by a partner in their lifetime, with even higher rates reported in sub-Saharan Africa (WHO 2013). Cross-sectional surveys have documented the adverse health impacts of IPV and the factors that increase risk of female victimisation and male perpetration. Nonetheless, theoretical and programmatic development has stalled due to lack of clarity on the temporality of identified associations: do documented associations represent risk factors for violence or do they reflect the consequences of abuse? This deficit of understanding is especially pressing in low and middle income countries (LMICs) where few longitudinal cohort studies with IPV as an outcome exist. This study seeks to address this gap by following forward in time a cohort of 1200 Tanzanian women, using state of the art methods to measure violence, encourage disclosure and ensure participant safety. Both quantitative and qualitative data will be collected at 4 discrete time points over 5 years, making this the largest longitudinal study of IPV ever undertaken in the developing world. In addition, an in-depth study of 40 men and a cross-sectional survey of 600 men will be conducted. The goal of the research is to advance our understanding of the predictors and consequences of IPV to better inform the design of interventions to reduce violence in LMICs. Specifically the study aims to: 1) advance the theoretical frameworks of intimate partner violence; 2) investigate the temporality of key factors linked to IPV; 3) map the dynamics of partner violence over time; 4) and investigate pathways leading to intimate partner violence. This research is of immediate necessity to address a vital public health challenge of our time and has the strong potential to have a long lasting impact on shaping the research agenda on intimate partner violence.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["716458"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["AKADEMIA SZTUKI W SZCZECINIE", "UNIVERZITA JANA EVANGELISTY PURKYNE V USTI NAD LABEM", "STOWARZYSZENIE EDUKACJA, NAUKA, KULTURA", "UNIVERSITA DEGLI STUDI DI MACERATA", "POLISH UNIVERSITY ABROAD"], "EU_Contribution": ["EUR 630 000"], "Project_Title": ["Technologies of Imaging in Communication, Art, and Social Sciences"], "Total_Cost": ["EUR 630 000"], "Country": ["Poland", "Czech Republic", "Poland", "Italy", "United Kingdom"], "Project_ACR": ["TICASS"], "Technology_Description": "In the face of images\u2019 proliferation in all areas of human life, we can talk about the necessity of education on how to adjust to and operate in visual space, to read even and develop the language reflecting such culture. ", "To": ["2021-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Poland"], "Activity": ["Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Other", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2017-05-01"], "Project_ID": ["734602"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA", "IMG PHARMA BIOTECH SOCIEDAD LIMITADA", "NANOVEX BIOTECHNOLOGIES SL", "UNIVERSIDAD COMPLUTENSE DE MADRID", "INESC MICROSISTEMAS E NANOTECNOLGIAS-INSTITUTO DE ENGENHARIA DE SISTEMAS DE COMPUTADORES PARA OS MICROSISTEMAS E AS NANOTECNOLOGIAS", "UNIVERSIDADE DO PORTO", "VIENNA BIOCENTER CORE FACILITES GMBH", "ICETA INSTITUTO DE CIENCIAS, TECNOLOGIAS E AGROAMBIENTE DA UNIVERSIDADE DO PORTO"], "EU_Contribution": ["EUR 846 000"], "Project_Title": ["Novel magnetic nanostructures for medical applications"], "Total_Cost": ["EUR 846 000"], "Country": ["Spain", "Spain", "Spain", "Spain", "Portugal", "Portugal", "Austria", "Portugal"], "Project_ACR": ["MAGNAMED"], "Technology_Description": "MAGNAMED designs, fabricates, and assesses novel magnetic nanostructures (MNS) with unique spin configurations for innovative diagnostics and therapy techniques. An early stage detection and an effective treatment are keystones to reduce cancer mortality. Current clinical procedures fail to detect small concentration of tumoral biomarkers. Magnetic nanoparticles (MNP), like beads, have attracted much attention for their capability to improve cancer detection limits and treatment technologies. However, there are several limitations to the use of MNP. As an emerging alternative, MNS are being explored. Unlike MNP, MNS (e.g. nanodisks) present a planar shape with novel properties for diagnosis: high magnetic moment and large size, which can significantly improve the sensor sensitivity, and for therapy: due to their planar shape, alternate magnetic fields provoke a magneto-mechanical action on the cell membrane that triggers cell death. The efficiency of MNS in these two medical applications has not been investigated yet for MNS at the nanometer scale. The challenge of this project is to produce MNS with nanometer dimensions suitable for medical applications. Several lithography techniques will be used to fabricate MNS in vortex and antiferromagnetic spin configurations covering a broad size range (40 to 4000 nm). After functionalization, MNS will be exploited in: (i) Diagnostics, using giant magnetoresistance (GMR) sensors for the detection of tumoral biomarkers (dermcidin and carcinoembryonic antigen), and (ii) Therapy, effectiveness of tumoral cell annihilation by the magneto-mechanical action of MNS will be evaluated in vitro assays of melanoma and colorectal cancer cells. MAGNAMED is a cross-sectoral and interdisciplinary project involving Physics, Chemistry and Medicine. Findings will have a medium-term impact on the European strategy for early stage detection of cancer and a long-term impact on the development of novel and groundbreaking therapeutics techniques.", "To": ["2021-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations"], "From": ["2017-04-01"], "Project_ID": ["734801"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["EUROPEAN MULTIDISCIPLINARY SEAFLOORAND WATER COLUMN OBSERVATORY - EUROPEAN RESEARCH INFRASTRUCTURE CONSORTIUM (EMSO ERIC)", "ISTITUTO NAZIONALE DI GEOFISICA E VULCANOLOGIA", "INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "NATURAL ENVIRONMENT RESEARCH COUNCIL", "HELLENIC CENTRE FOR MARINE RESEARCH", "INNOVA SRL", "MARINE INSTITUTE", "UNIVERSITAT POLITECNICA DE CATALUNYA", "INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU GEOLOGIE SI GEOECOLOGIE MARINA-GEOECOMAR", "INSTITUTO PORTUGUES DO MAR E DA ATMOSFERA IP"], "EU_Contribution": ["EUR 4 359 451,25"], "Project_Title": ["Implementation of the Strategy to Ensure the EMSO ERIC\u2019s Long-term Sustainability"], "Total_Cost": ["EUR 4 370 279,41"], "Country": ["Italy", "Italy", "France", "France", "United Kingdom", "Greece", "Italy", "Ireland", "Spain", "Romania", "Portugal"], "Project_ACR": ["EMSO-Link"], "Technology_Description": "EMSO-Link is a 3-year project underpinning the long-term sustainability of EMSO ERIC, the pan-European distributed Research Infrastructure (RI) composed of fixed point open ocean observatories for the study and monitoring of European seas. EMSO pursues the long-term objective to be part of the upcoming European Ocean Observing System (EOOS), which is expected to integrate multiple platforms and data systems, including other ERICs, to achieve the first sustained, standardized and permanent observatory network of the European seas. EMSO ERIC coordinates the access to the facilities and supports the management of data streams from EMSO observatories. ", "To": ["2020-02-29, ongoing project"], "Meta": [""], "Topic_s": ["INFRADEV-03-2016-2017 - Individual support to ESFRI and other world-class research infrastructures"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations"], "From": ["2017-03-01"], "Project_ID": ["731036"], "Call_for_Proposal": ["H2020-INFRADEV-2016-1"]}, -{"Partners": ["SZKOLA GLOWNA GOSPODARSTWA WIEJSKIEGO", "SZKOLA GLOWNA GOSPODARSTWA WIEJSKIEGO"], "EU_Contribution": ["EUR 1 413 750"], "Project_Title": ["Entrapment of Hypoxic Cancer by Macrophages Loaded with HAP"], "Total_Cost": ["EUR 1 413 750"], "Country": ["Poland", "Poland"], "Project_ACR": ["McHAP"], "Technology_Description": "The proposed project seeks to open a new research front within the field of drug delivery to the solid tumours. Unsatisfactory response of tumours to chemotherapy is mainly related to impaired diffusion of the anticancer drug because of decreased drug uptake due to poor vasculature. Moreover, the drug is not able to penetrate the most hypoxic sites. Cells from these \u2018untreated\u2019 sites are responsible for relapse and metastasis. However, these avascular regions attract macrophages that migrate even to areas far away from blood vessels. Therefore, they might constitute a unique delivery system of drug containing particles to these parts of the tumour mass. A promising example of such particles that could be used are ferritins, whose caged architecture allows for efficient drug encapsulation and whose uptake from macrophage cells has been well demonstrated. My recent ground breaking finding was that macrophages are also able to specifically and actively transfer these taken up ferritins (loaded with the compound of choice) to cancer cells. Thus, these preliminary results indicate the possibility to use macrophages to deliver ferritin encapsulated compounds directly to the tumour cells even in its hypoxic areas. Then, the use of hypoxia-activated prodrugs (HAP) which are selectively activated only in hypoxic regions will be exploited in order to make cancer therapy safer. However, the molecular mechanism of ferritin uptake by macrophages, their storage, and transport to the cancer cells represent key issues to be investigated and pave the way to the experimental design of the present project. ", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Poland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["715048"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["HERIOT-WATT UNIVERSITY", "THALES ALENIA SPACE FRANCE", "LARGE SPACE STRUCTURES GMBH", "AURORA SOFTWARE AND TESTING S.L.", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "FUNDACION PRODINTEC"], "EU_Contribution": ["EUR 1 834 895,07"], "Project_Title": ["Radio Technologies for Broadband Connectivity in a Rapidly Evolving Space Ecosystem: Innovating Agility, Throughput, Power, Size and Cost"], "Total_Cost": ["EUR 1 834 895,07"], "Country": ["United Kingdom", "France", "Germany", "Spain", "France", "Spain"], "Project_ACR": ["REVOLVE"], "Technology_Description": "Radio signals are core to space systems and services; they are the backbone of satellite broadcasting & communications and further represent the primary underpinning technology of the nearly ubiquitous space-based radio navigation services as well as a large number of Earth observation instruments. Radio technologies are therefore central in defining the investment return for a wide range of missions and reflect to a significant fraction of the combined space and ground segment infrastructure. As the frightening rates of concurrent advances in space-related services, business models and technologies are driving the space ecosystem to a new age, the need to re-invent radio technologies for space is becoming increasingly urgent; while the sector is proactively looking for the next game changer, a whole new class of emerging and forecasted missions place urgent demands for drastic reduction in cost with a concurrent radical improvement in throughput, agility, volume/mass and power consumption. ", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations"], "From": ["2017-01-01"], "Project_ID": ["722840"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["UNIVERSITEIT LEIDEN", "UNIVERSITEIT LEIDEN", "UNIVERSITE DE LIEGE"], "EU_Contribution": ["EUR 2 500 000"], "Project_Title": ["Rural Riches. The bottom-up development of Post-Roman Northwestern Europe (450-640)"], "Total_Cost": ["EUR 2 500 000"], "Country": ["Netherlands", "Netherlands", "Belgium"], "Project_ACR": ["Rural Riches"], "Technology_Description": "The question as to how Europe emerged from the collapse of the Roman state in the West has been the subject of academic debate for over a century. Most modern authors agree on the idea that the post-Roman economic development was the result of the initiatives and the demand of the elite. This paradigm of elite control of production and (long-distance) trade seems to be at odds with the vast amounts of objects, often precious and of exotic origin, that are found in the thousands of richly furnished cemeteries of even the smallest rural communities. ", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["741340"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITAET HAMBURG", "UNIVERSITY OF YORK", "ERASMUS UNIVERSITEIT ROTTERDAM", "FACULDADE DE ECONOMIA DA UNIVERSIDADE NOVA DE LISBOA", "UNIVERSIDADE NOVA DE LISBOA", "UNIVERSITA COMMERCIALE LUIGI BOCCONI", "SYDDANSK UNIVERSITET", "ST JUDE MEDICAL COORDINATION CENTER"], "EU_Contribution": ["EUR 3 877 749,36"], "Project_Title": ["Improving Quality of Care in Europe"], "Total_Cost": ["EUR 3 877 749,36"], "Country": ["Germany", "United Kingdom", "Netherlands", "Portugal", "Portugal", "Italy", "Denmark", "Belgium"], "Project_ACR": ["IQCE"], "Technology_Description": "Improving quality of care has been given too little attention in health economic research in the past although it is the central goal of health care systems in Europe. The proposed ETN on \u201cImproving Quality of Care in Europe (IQCE)\u201d aims to address this gap and has the following aims: 1) Create new evidence and improve existing health economic research in the field of quality of care. Research gaps are addressed by empirical, theoretical and experimental approaches with a focus on innovative econometric methods using novel access to databases. 2) Establish a close link of the topical PhD projects to health policy and practice ensuring high relevance and practical applicability of results. Implementation of project results can potentially enhance performance of European health care systems. 3) Train PhD fellows to be experts in the field of quality of care and obtain excellent profiles for different career paths in health economic research or practice. 4) contribute to better coordination of currently fragmented health economic research in Europe. This will improve the competitive position of European health economic research. 5) serve as a model for joint doctorate programmes in health economics in Europe. This will drive the development of PhD programmes in health economics in Europe, which currently are scarce.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["721402"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Decoding planetary compositions using observations and modelling of planet-forming disks"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["DISCO"], "Technology_Description": "Our sun is host to eight planets, and recent discoveries have revealed that there is at least one planet per star in the Galaxy. Moreover, small, rocky planets like the Earth outnumber the Jupiter-like gas giants. The bulk elemental composition of most planets is not yet known, but evidence from the solar system and some extrasolar (proto-)planetary systems suggests there are considerable variations in the abundance of elements such as carbon, chlorine, iron and others. Some of these variations are seen in the rocky planets, others apply to atmospheres of giant planets. Understanding this diversity is important, as the Earth's elemental budget is key to various aspects of its habitability. Therefore, we must understand the origin of planetary compositions if we are to scientifically estimate the number of habitable worlds. In the DISCO project, I will study the elemental abundances in the inner and outer regions of planet-forming disks around young stars and will build models to capture the main processes that affect the gas-ice-refractory balance of specific elements. These analytical models will be implemented in a chemically-based planet population synthesis calculation which can be compared with known planetary compositions and will allow to predict the distribution of elemental compositions of exoplanets.", "To": ["2019-07-02, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-03"], "Project_ID": ["753799"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["PULsar Science Across The Electromagnetic Spectrum"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["PULSATES"], "Technology_Description": "Over the last 50 years the study of pulsars has advanced our scientific knowledge over an incredibly broad range of topics, from particle physics, where they provide the only means of experimentally testing theories that describe the behaviour of matter at densities greater than those in an atomic nucleus, to enabling exquisitely precise tests of gravity. Since their initial discovery, over 2000 pulsars have been found in surveys worldwide, and observed from 100 MHz up to TeV gamma-ray energies, however ten times more than this are expected to be observable in our Galaxy.", "To": ["2019-09-30, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-10-01"], "Project_ID": ["748941"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF SOUTHAMPTON"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Black Holes in String Theory and Holography"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["BH-STRING-HOLO"], "Technology_Description": "Black holes are among the most fascinating and enigmatic objects in our universe. The internal structure of black holes is of significant interest for quantum gravity, for astrophysical phenomena, and for the study of quantum entanglement in systems with many degrees of freedom. ", "To": ["2019-09-30, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["747665"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF WARWICK"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Prisoners of war between Bourbon nations and United Kingdom during the 18th Century: ways of life and humanity in misfortune"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["PriWa"], "Technology_Description": "Armies of the Ancien R\u00e9gime reflected not only the society of their time, but also the politics, importance and international weight of their respective nations. Prisoners of war offer a privileged insight into these issues and, more significantly, into the human and humanitarian feelings of all those involved, politicians and civilians as well as the military. This study will provide a ground-breaking comparative approach to prisoners of war from Britain, Spain and France during the long 18th century. Through correspondence written by the prisoners themselves as well as letters to/by the authorities, we will chart feelings and views towards the conflicts from those directly involved, revealing alternative views of war than those imposed by their sovereigns. In what the prisoners conveyed to their families and to the authorities, we can learn much of the conditions of captivity, which varied considerably depending on religion, social status or military rank. Across the century, we find analogous prisoner of war experiences in different societies and historical periods, but after the French Revolution significant differences begin to emerge because of new political considerations which meant qualitative changes to the status of prisoners of war, since they were henceforth political prisoners, no longer Ancien R\u00e9gime ones. Comparing Britain and Spain with France is essential to perfecting our understanding of how the status and experience of prisoners of war changed between the old order and the new. In brief, this is a study that helps to understand better the changes in the humanitarian measures in war which form the basis of current practice and are at the heart of notions of Human rights.", "To": ["2019-07-02, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-03"], "Project_ID": ["746995"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CIENCIA VIVA-AGENCIA NACIONAL PARA A CULTURA CIENTIFICA E TECNOLOGICA", "INSTITUTO DE BIOLOGIA MOLECULAR E CELULAR-IBMC", "UNIVERSIDADE NOVA DE LISBOA", "INSTITUTO DE TECNOLOGIA QUIMICA E BIOLOGICA - UNIVERSIDADE NOVA DE LISBOA", "UNIVERSIDADE DE COIMBRA"], "EU_Contribution": ["EUR 153 000"], "Project_Title": ["Foreseeing Opportunities, Risks and Emergent Science Issues for the next Generation: Highlighting Trends"], "Total_Cost": ["EUR 153 000"], "Country": ["Portugal", "Portugal", "Portugal", "Portugal", "Portugal"], "Project_ACR": ["FORESIGHT"], "Technology_Description": "Our proposal for ERN 2016-17 is focussed on foresight, exploring alternatives to consider and manage the future with researchers and the public, envisioning new trends of science and technologies and of their impacts on society. Of special concern are the complex problems and challenges that humanity faces: climate change, sustainable energy, food and water supply, ageing and social inclusion, to name but a few of the global trends identified for the next 10-15 years.", "To": ["2017-11-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-NIGHT-2016 - European Researchers' Night"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Portugal"], "Activity": ["Other", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["722968"], "Call_for_Proposal": ["H2020-MSCA-NIGHT-2016"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 200 194,80"], "Project_Title": ["An exploration into the feasibility of simultaneously achieving \u2018No Net Loss\u2019 of biodiversity and ecosystem services, in an uncertain and changing world"], "Total_Cost": ["EUR 200 194,80"], "Country": ["Denmark"], "Project_ACR": ["NNL"], "Technology_Description": "We are evidently currently witnessing an ongoing loss of global biodiversity, caused largely by anthropogenic activity, and thought to be resulting in a loss of associated ecosystem services. However, the economic development that often leads to net loss of ecosystem services also provides benefits to humanity. An optimal balance between development and biodiversity conservation must be found.", "To": ["2017-08-31, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["655497"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["KAROLINSKA INSTITUTET"], "EU_Contribution": ["EUR 185 857,20"], "Project_Title": ["Development of a high-resolution method to monitor structural changes of regulatory RNAs and therapeutic oligo-nucleotides directly in-cell."], "Total_Cost": ["EUR 185 857,20"], "Country": ["Sweden"], "Project_ACR": ["RNAatHD"], "Technology_Description": "MicroRNAs (miRNAs) are master regulators in cells with a complexity yet to be unraveled. By targeting one or more messenger RNAs (mRNAs) they affect a vast number of biological processes and are associated with a broad spectrum of diseases, including cancer. This makes them potential candidates for cancer-diagnostics and -therapeutics. This opportunity can only be fully exploited by a better comprehension of how and when each mRNA is targeted by a miRNA, a fact, which is currently still poorly understood. Besides regulatory RNAs, synthetic \u201canti-sense\u201d oligonucleotides (AONs) are currently tested as cancer drugs. Progress in this field has been slow due to unspecific off-target-effects i.e. the lack of understanding, of the mechanism of AONs targeting mRNAs. This project focuses on overcoming this lack of knowledge of the targeting process. To understand the intermolecular interactions occurring in the cell we will, for the first time, monitor the molecular structure and structural changes (dynamics) of nucleotides (miRNAs as well as AONs) in the living cell, and link these in-cell structures to the molecule\u2019s targeting function. Combining existing knowledge of the host in structural and molecular biology of miRNAs with the experience in methods development in Nuclear Magnetic Resonance (NMR) of the experienced researcher (ER), we will develop a set of robust and reliable in-cell NMR methods to determine cellular concentration, structure and dynamics within the cell at high resolution. The scope of the method will be demonstrated on: (i) a miRNA, miR-34a, which targets more than 50 different mRNAs, related to cancer and other cellular processes, as well as (ii) an AON drug candidate in collaboration with AstraZeneca. This project will benefit drug development against various diseases and will enable the ER to contribute to solving today's health problems and develop further towards becoming a future group leader on the interface of research in academia and industry.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["747446"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["STICHTING KATHOLIEKE UNIVERSITEIT", "STICHTING KATHOLIEKE UNIVERSITEIT"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Synthetic DCs for a T cEll ProdUction Platform"], "Total_Cost": ["EUR 150 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["STEPUP"], "Technology_Description": "Cancer immunotherapy and adoptive transfer of genetically manipulated T cells in particular has shown promising results for the treatment of cancer. Central in cancer immunotherapy is the activation of tumour-specific T cells. However, the wide-spread clinical use of T cell therapies remains limited due to costly, time-consuming and labour-intensive processes associated with the ex vivo activation and expansion of tumour-specific T cells. Artificial antigen presenting cells (aAPCs) have been developed as an alternative for efficient activation of T cells. In the ERC project \u2018PATHFINDER\u2019, Prof. Figdor and his team have developed aAPCs or synthetic dendritic cells (sDCs) based on highly flexible polyisocianide (PIC) polymers, that mimic naturally occurring DCs. The semi-flexible polymer backbone allows for proper arrangement and clustering of antigen and (co-)stimulatory markers, resulting in potent activation and expansion of T cells. With the use of PIC based sDCs, we propose a production platform for tumour specific T cells suitable for cancer immunotherapy. In this ERC PoC project, a team of technological and commercial experts will investigate commercial feasibility of this innovative approach.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["755402"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["KAROLINSKA INSTITUTET"], "EU_Contribution": ["EUR 185 857,20"], "Project_Title": ["Skeletal Muscle Inflammation: ambivalent roles in Exercise and Diabetes"], "Total_Cost": ["EUR 185 857,20"], "Country": ["Sweden"], "Project_ACR": ["SMILED"], "Technology_Description": "In Europe, 52 million people are living with diabetes, with more than 90% of them having type 2 diabetes (T2D), a multifactorial disease associated with obesity and sedentary lifestyle. It leads to severe complications such as cardiovascular events and constitutes an unmanageable economic burden. Skeletal muscle inflammation is emerging as a potential contributor to T2D. Inflammation occurs during exercise and repair and is a hallmark of myopathies, suggesting that it plays crucial roles in skeletal muscle homeostasis. Despite the fact that exercise is associated with inflammation, physical activity has beneficial effects on T2D, which highlights the ambivalent role of muscle inflammation in controlling glucose homeostasis.", "To": ["2018-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["704978"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["KAROLINSKA INSTITUTET"], "EU_Contribution": ["EUR 265 059"], "Project_Title": ["Mechanisms of cellular fatty acid homeostasis"], "Total_Cost": ["EUR 265 059"], "Country": ["Sweden"], "Project_ACR": ["TGDNL"], "Technology_Description": "The ability of cells to precisely maintain an internal steady state of lipids is essential for life. While homeostatic mechanisms controlling specific lipids such as sterols are well characterized, the regulation and coordination of fatty acid (FA) and triacylglycerol (TG) synthesis remains largely unknown. Several common metabolic disorders, including obesity and type 2 diabetes, lead to nonalcoholic fatty liver disease (NAFLD), a condition characterized by increased accumulation of hepatic TGs. Since a significant proportion of subjects with NAFLD develop potentially fatal complications, e.g. non-alcoholic steatohepatitis (NASH) and cirrhosis, it is of fundamental importance to study the mechanisms that promote hepatic lipid accumulation. By combining advanced molecular techniques with state-of-the-art clinical research, a translational approach will be applied herein to uncover how cells coordinate glycerolipid and FA synthesis. The studies focus on acyl-CoA:diacylglycerol O-transferase 2 (DGAT2), an enzyme catalysing the final step of TG biosynthesis and a drug target for NAFLD, which according to recent data may play an important role in FA synthesis regulation. The results generated in this project may uncover novel mechanisms controlling cellular lipid homeostasis and provide new therapeutic avenues to treat NAFLD and NASH.", "To": ["2020-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["704647"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 200 194,80"], "Project_Title": ["Global and local star formation with state-of-the-art physics"], "Total_Cost": ["EUR 200 194,80"], "Country": ["Denmark"], "Project_ACR": ["AdvancedStarForm"], "Technology_Description": "New stars form within large turbulent complexes harboring several thousands of solar masses of cold gas: the molecular clouds. The diffuse gas collapses gravitationally and heats up via compression until nuclear fusion reactions ignite and the star comes to life. The full description involves an intricate interplay between large-scale environmental factors and small-scale processes close to the star, connecting a number of physical mechanisms, including magnetic fields, self-gravity, radiative transfer, and time dependent chemistry.", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["659706"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 212 194,80"], "Project_Title": ["Mixotrophy among small marine phytoflagellates \u2013 prevalence and impact on prokaryotic communities"], "Total_Cost": ["EUR 212 194,80"], "Country": ["Denmark"], "Project_ACR": ["MARIS"], "Technology_Description": "Mixotrophy, i.e. the use of photosynthesis and prey uptake for growth, is increasingly recognized as a major trophic strategy for small (\u2264 20 \u00b5m) phytoflagellates, which are responsible for a significant fraction of global primary production. In fact, marine primary production in many areas is now thought to be supported by organic P and Fe derived from prey. Despite this, a consistent picture of the overall relevance of bacterivory in open ocean and coastal mixotrophic small phytoflagellates (MSP) is lacking. Additionally, a strict dichotomy between `phytoplankton\u00b4 and `zooplankton\u00b4 is still overwhelmingly employed in models predicting the flow of matter and energy through marine systems, leading to potentially flawed and misleading predictions on ecosystem productivity and the health of global fisheries. This is especially significant when considering that anticipated environmental changes related to climate change are expected to shift the phototrophy/mixotrophy balance, with largely unknown consequences. The present study will combine culture and field work to 1) determine how shifts in environmental conditions related to e.g. season, influence coastal MSP abundance, identity and bacterivorous impact on the whole prokaryotic community, and on specific prokaryotic groups, such as unicellular cyanobacteria; and 2) analyze the importance and basic regulation of bacterial uptake for understudied coastal MSP. The proposed project excellently fuses the expertise areas of the experienced researcher, Dr. Anderson (bacterivory and predator-prey interactions), with the supervisor, Prof. Hansen (mixotrophic phytoflagellates) and the international collaborators, Prof. J\u00fcrgens (protist diversity and microbial food web interactions) and Prof. Scanlan (unicellular cyanobacteria), leading to an optimal exchange of knowledge for a successful project outcome. It will additionally restart and further the promising scientific career of Dr. Anderson after her maternity break.", "To": ["2017-04-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-05-01"], "Project_ID": ["658882"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["KAROLINSKA INSTITUTET", "KAROLINSKA INSTITUTET"], "EU_Contribution": ["EUR 2 443 952,50"], "Project_Title": ["Decomposition of pain into celltypes"], "Total_Cost": ["EUR 2 443 952,50"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["PainCells"], "Technology_Description": "Almost 20% of the population has an ongoing pain problem. Pain is caused by a complex recruitment of different types of sensory neurons with different response-profiles and hence, the integrated response of an assembly of different neuronal types results in pain. Due to technical limitations, a system-wide approach to resolve the complexity of cell types and their involvement in the development of pain has yet not been tried.", "To": ["2022-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["740491"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["CENTRO EM REDE DE INVESTIGACAO EM ANTROPOLOGIA", "CENTRO EM REDE DE INVESTIGACAO EM ANTROPOLOGIA"], "EU_Contribution": ["EUR 1 192 144"], "Project_Title": ["CRITICAL APPROACHES TO POLITICS, SOCIAL ACTIVISM, AND ISLAMIC MILITANCY IN THE WESTERN SAHARAN REGION"], "Total_Cost": ["EUR 1 192 144"], "Country": ["Portugal", "Portugal"], "Project_ACR": ["CAPSAHARA"], "Technology_Description": "This project proposes an analysis of the reconfigurations established in the socio-political vocabulary of the western Saharan region \u2013 southern Morocco, Western Sahara and Mauritania \u2013 from the \u201cpost-empire\u201d to the contemporary period. The project should produce an analysis of 1) the social and political structures shared in the region, 2) the local variations of those structures, based on case studies, 3) their specific configurations, based on social markers such as gender, age, and class, 4) the use of those structures in different historical periods. All these will be under theoretical and ethnographic scrutiny in order to achieve its main goal: 5) to understand the recent articulation of the social and political structures of the Western Saharan region, with broader and often exogenous political vocabularies. ", "To": ["2021-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Portugal"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-04-01"], "Project_ID": ["716467"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["ECOLE POLYTECHNIQUE", "THE REGENTS OF THE UNIVERSITY OF CALIFORNIA"], "EU_Contribution": ["EUR 264 668,40"], "Project_Title": ["Solar Wind Heating and Turbulence"], "Total_Cost": ["EUR 264 668,40"], "Country": ["France", "United States"], "Project_ACR": ["SoWHat"], "Technology_Description": "Observations of solar wind (SW) turbulence have usually emphasized magnetohydrodynamic (MHD) scales where the Kolmogorov scaling f \u22125/3 of the magnetic spectra is frequently observed. These spectra are", "To": ["2018-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-11-01"], "Project_ID": ["661472"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA", "THE REGENTS OF THE UNIVERSITY OF CALIFORNIA"], "EU_Contribution": ["EUR 244 269"], "Project_Title": ["A mood-indexed database of scores, lyrics, musical excerpts, vector-based 3D animations, and dance video recordings"], "Total_Cost": ["EUR 244 269"], "Country": ["Italy", "United States"], "Project_ACR": ["MUSICAL-MOODS"], "Technology_Description": "The project aims at the development of an online database of scores, lyrics and musical excerpts, vector-based 3D animations, and dance video recordings, indexed by mood. Such a taxonomy of relations between the musical, linguistic and motion domains will be aimed at interactive music systems and music making. For realising the database, digital scores inclusive of lyrics will be gathered from collections of music in the public domain. Music mood classification using audio and metadata will aim at capturing sophisticated features but using no explicit domain-specific knowledge about a mental state. Datasets will be realised through a cross-modal approach. Validation of the model will be carried out by combining results from an online game-with-a-purpose, for Internet users, and from intermedia case studies for selected dancers. In further case studies, music works will be realised, also by invited artists, for the evaluation of the database in interactive music making. An online call for artists to use the database in music making or sound generation will be aimed at extending the evaluation further. The final database will be made available online for further exploitation. The present research will generate new knowledge for use in next-generation systems of interactive music and music emotion recognition, also contributing to extend the investigation in the broader areas of music making, computational creativity and information retrieval.", "To": ["2018-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-12-01"], "Project_ID": ["659434"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE QUEEN'S UNIVERSITY OF BELFAST", "DUBLIN CITY UNIVERSITY", "CRANFIELD UNIVERSITY", "UNIVERSITAET DUISBURG-ESSEN", "IWW RHEINISCH WESTFALISCHES INSTITUT FUR WASSERFORSCHUNG GEMEINNUTZIGE GMBH", "TECHNISCHE UNIVERSITAT DORTMUND", "SUPREN GMBH", "KOBENHAVNS UNIVERSITET", "UNIVERSITA DEGLI STUDI DI TORINO", "T.E. LABORATORIES LIMITED"], "EU_Contribution": ["EUR 3 722 227,71"], "Project_Title": ["Improved decision-making in contaminated land site investigation and risk assessment"], "Total_Cost": ["EUR 3 723 227,71"], "Country": ["United Kingdom", "Ireland", "United Kingdom", "Germany", "Germany", "Germany", "Germany", "Denmark", "Italy", "Ireland"], "Project_ACR": ["Remediate"], "Technology_Description": "The REMEDIATE ETN comprises 10 beneficiaries (from 5 EU Member States \u2013 the UK, Ireland, Germany, Denmark, and Italy) and 15 partner organisations. The beneficiaries and partner organisations are committed to the provision of innovative research and training for more cost effective and sustainable remediation of contaminated land. It is a multidisciplinary collaboration between internationally renowned research teams (from both the academic and non-academic sectors) each with complementary expertise in a wide range of site investigation and risk assessment technologies. 14 Early Stage Researchers (ESRs) will be recruited into the network and will participate in a structured and integrated research and training programme that will provide them with a highly specific blend of personalised technical and transferable skills. Each research project is designed to benefit the contaminated land sector through development of techniques and tools across a range of disciplines relating to site investigation and risk assessment, to provide better informed solutions for remediation. The unique provision of joint supervision (from both the academic and non-academic sectors) and non-academic mentoring will significantly enhance the fellows\u2019 career prospects within the contaminated land sector. The REMEDIATE ETN will strengthen and enhance existing collaborations between the participating beneficiaries and partner organisations resulting in a cohesive and dynamic network. The output will be a new generation of highly mobile, creative and innovative entrepreneurs with the skills sets necessary to address the technical, economic and social challenges facing the contaminated land sector in Europe, both now and in the future.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["643087"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["UNIVERSITAET BASEL", "UNIVERSITAET BASEL"], "EU_Contribution": ["EUR 1 498 961"], "Project_Title": ["Modular mechanical-atomic quantum systems"], "Total_Cost": ["EUR 1 498 961"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["MODULAR"], "Technology_Description": "Atomic ensembles are routinely prepared and manipulated in the quantum regime using the powerful techniques of laser cooling and trapping. To achieve similar control over the vibrations of nanofabricated mechanical oscillators is a goal that is vigorously pursued, which recently led to the first observations of ground-state cooling and quantum behavior in such systems.", "To": ["2020-12-31, ongoing project |"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["677548"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["UNIVERSITY OF GREENWICH", "UNIVERSITA DEGLI STUDI DELL'AQUILA", "UNIVERSITEIT TWENTE", "SERVICE DEPARTEMENTAL D'INCENDIE ET DE SECOURS DE LA HAUTE-CORSE", "ENTENTE POUR LA FOR\u00caT M\u00c9DITERRAN\u00c9ENNE", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "FUNDACIO D'ECOLOGIA DEL FOC I GESTIO D'INCENDIS PAU COSTA ALCUBIERRE", "UNIVERSIDAD COMPLUTENSE DE MADRID", "UNIVERSITE DE GENEVE", "UNIVERSITA DEGLI STUDI DI PERUGIA", "UNIVERSITE CLERMONT AUVERGNE", "UNIVERSITE DE TECHNOLOGIE DE COMPIEGNE", "UNIVERSITE PARIS DAUPHINE", "ECOLE DE MANAGEMENT DE NORMANDIE", "ROYAL MELBOURNE INSTITUTE OF TECHNOLOGY*RMIT UNIVERSITY", "BUSHFIRE AND NATURAL HAZARDS CRC LIMITED", "UNIVERSITY OF MELBOURNE"], "EU_Contribution": ["EUR 1 080 000"], "Project_Title": ["Geospatial based Environment for Optimisation Systems Addressing Fire Emergencies"], "Total_Cost": ["EUR 1 386 000"], "Country": ["United Kingdom", "Italy", "Netherlands", "France", "France", "France", "Spain", "Spain", "Switzerland", "Italy", "France", "France", "France", "France", "Australia", "Australia", "Australia"], "Project_ACR": ["GEO-SAFE"], "Technology_Description": "In EU and Australia, every year thousands of square miles of forests and other lands burn due to wildfires. These fires cause important economic and ecological losses, and often, human casualties. Both EU and Australian governments are aware of how crucial it is to improve wildfires\u2019 management and containment . Scientists from different specialties, both in EU and Australia, have already developed methods and models in order to improve the management and decision process pertaining to preparedness and response phases in case of bushfire. The present project, named Geospatial based Environment for Optimisation Systems Addressing Fire Emergencies (GEO SAFE), aims at creating a network enabling the two regions to exchange knowledge, ideas and experience , thus boosting the progress of wildfires knowledge and the related development of innovative methods for dealing efficiently with such fires. ", "To": ["2020-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["691161"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI CAGLIARI", "KINGSTON UNIVERSITY HIGHER EDUCATION CORPORATION", "THE WALT DISNEY COMPANY (SWITZERLAND) GMBH", "DEUTSCHE TELEKOM AG", "UNIVERSITY OF PLYMOUTH", "NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU", "HOLOGRAFIKA HOLOGRAMELOALLITO FEJLESZTO ES FORGALMAZO KFT"], "EU_Contribution": ["EUR 2 883 122,64"], "Project_Title": ["innovative Quality Of Experience maNagement in Emerging mulTimedia services"], "Total_Cost": ["EUR 2 883 122,64"], "Country": ["Italy", "United Kingdom", "Switzerland", "Germany", "United Kingdom", "Norway", "Hungary"], "Project_ACR": ["QoE-Net"], "Technology_Description": "The realization of the paradigm of Internet anywhere, anytime and any-device and the diffusion of end-user multimedia devices with powerful and user-friendly capabilities such as smartphones, tablets PCs, mobile gaming terminals and e-books, are leading to the proliferation of a significant amount of emerging multimedia services: immersive environments, mobile online gaming, 3D virtual world, book/newspaper consumption, social networking, IPTV applications, just to cite a few. Some of these services have already reached a major market success, such as the case of newspaper/magazine mobile readers and smartphone multimedia apps. Their success has been achieved especially because a user-centered approach has been followed to design the whole process of content production, service activation, content consumption, service management and updating. From these considerations it arises that management of the Quality of Experience (QoE) is undoubtedly a crucial concept in the deployment of future successful services and it is straightforward to be understood but complex to be implemented in real systems, since there are many variables which will affect QoE, and these variables are changeable and span multidisciplinary areas including multimedia signal processing, communications, computer networking, psychology and sociology. ", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["643072"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["UNIVERSITEIT TWENTE"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["Empowering parents through the development of an online evidence-based mental health promotion school engagement resource"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["EMPOWER"], "Technology_Description": "The promotion of children\u2019s mental health and wellbeing is fundamental to achieving strategic objectives of the EU health policy. Schools are recognised as a key setting to support and enhance children\u2019s social and emotional wellbeing. Evidence to date indicates that school interventions have the greatest impact when they are focused on linking children, teachers and parents in the promotion of positive mental health. To date, however, there is an absence of research and resources to assist schools in supporting parental engagement in mental health promotion. The proposed research aims to address this crucial gap in school mental health. The study will adopt a systematic approach to developing an evidence-based resource for primary schools which is designed to assist school staff in establishing collaborative relationships with parents and align parent and teacher practices in promoting children\u2019s mental health. In order to achieve this, the applicant will (i) systematically review current evidence on existing school-parent engagement frameworks and resources (ii) develop an online school-parent engagement resource based on the current evidence and consultation with school community stakeholders (iii) evaluate the implementation and efficacy of the online resource when implemented as part of a whole school mental health intervention that is being trialled in ten primary schools in Twente. This research will be carried out in collaboration with Prof Bohlmeijer at the Dept. of Psychology, Health and Technology and the Centre of eHealth Research and Disease Management at the University of Twente. The applicant will receive expert training from the Centre of eHealth Research in the development of technology supported mental health interventions. Under the guidance of Prof Bohlmeijer, the applicant will advance her research, management and networking skills and will generate an innovative research niche producing questions for investigation beyond the life of this study.", "To": ["2018-01-03, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-07-06"], "Project_ID": ["655950"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UPPSALA UNIVERSITET"], "EU_Contribution": ["EUR 233 111,60"], "Project_Title": ["Temporality of permanence \u2013material and socio-spatial practices in African urbanism"], "Total_Cost": ["EUR 233 111,60"], "Country": ["Sweden"], "Project_ACR": ["TEMPEA"], "Technology_Description": "The constructed materiality of African urbanism can be seen in buildings and the urban layout, especially when they aspire to permanence by building in stone. These built environments have mostly been analysed through the rather static lens of individual periods and social forces, resulting in uniformly interpreted organic growth (for pre-colonial periods), or as in stages of progress towards the fulfilment of a grand master plan (predominantly in the colonial and post-colonial era). This project seeks to explore the social temporality of African urbanism against the context of its material complements from the perspectives of a range of social and human sciences, in order to obtain a dynamic picture from before to after the colonial era. I aim to provide analyses relevant to the ever more pressing issues of urban ethnic/social coexistence and the implications of urban development.", "To": ["2018-05-13, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-14"], "Project_ID": ["656767"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["STOCKHOLMS UNIVERSITET"], "EU_Contribution": ["EUR 173 857,20"], "Project_Title": ["Water Coalitions: A Comparative Analysis of Agenda Implementation Strategies in Peru and Brazil through the Study of Basin Councils."], "Total_Cost": ["EUR 173 857,20"], "Country": ["Sweden"], "Project_ACR": ["Water Coalitions"], "Technology_Description": "This project aims at establishing and explaining the reasons behind coalition formation and coalition sustainability in water management. It sets its scope on selected basin councils operating in two Latin American countries, Peru and Brazil. Both countries, and the Latin American region in general, have faced numerous conflicts around water management in the past. The relationships between the state and civil society movements over water have been presented as dichotomous, dismissing the complexities of the \u2018street-level bureaucrat\u2019 category. To fill in that gap, this project asks: \u2018what kind of coalitions do bureaucrats and social leaders establish to institutionalise and strengthen specific visions of water management?\u2019 Coalitions are defined as groups of actors who have joined forces to accomplish common objectives. The project investigates (i) the types and characteristics of coalitions between bureaucrats and activists, (ii) the factors that explain coalition formation and membership and, (iii) the relationships between different coalitions. Peru and Brazil are similarly organized through basin councils and a national water authority. Yet, they have three important differences that would lead to fruitful comparison: the level of decentralization, the vision of water institutionalised and, the approach to social participation. This study will shed light on the power differentials between bureaucracies and on the tools available for weak bureaucracies to advance in their agendas. In order to explore these issues I will combine the Advocacy Coalition Framework with the Social-Ecological Systems framework and analyse the data through a cross-case methodology. The project will produce a model on coalition formation and behaviour. Investigating coalition formation and behaviour is urgent if we are to provide multi-actor water governance the tools to perform better than traditional approaches.", "To": ["2017-09-06, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-07"], "Project_ID": ["660394"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITY OF PLYMOUTH", "UNIVERSITEIT GENT", "THE UNIVERSITY OF LIVERPOOL", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 288 000"], "Project_Title": ["Integrating isotopic techniques with Bayesian modelling for improved assessment and management of global sedimentation problems"], "Total_Cost": ["EUR 288 000"], "Country": ["United Kingdom", "Belgium", "United Kingdom", "Spain"], "Project_ACR": ["IMIXSED"], "Technology_Description": "This international RISE programme brings together EU, North American, African and Asian scientists to deliver a powerful tool for sediment management. Siltation of river channels, lakes and reservoirs presents a credible threat to river basin ecosystem service provision and water security. River silt originates in the catchment and the primary driver for mobilisation and translocation downstream is agriculture where loss of soil from slopes threatens food security. Knowledge of sediment source, transfer and residence time dynamics is critical to inform management for future food and water security and cutting-edge nuclear techniques have been developed in a joint UN Food and Agriculture Organisation and International Atomic Energy Agency Coordinated Research Programme to trace river silt back to source. However, the game change in isotopic biogeochemical tracer sophistication has led to a step change in data complexity. While these datasets capture real world complexity in time and space, the conventional statistical approaches to quantify sediment provenance from the tracer data do not. This severely limits the power of isotopic techniques for sediment source apportionment. Advances in ecological source apportionment models based on Bayesian statistics, however, present opportunity. New models, i.e. MixSIAR, have been shown to appropriately address such variability in a quantitative way and, if tailored to river basin sediment tracer data offer to address the above challenge. The central goal is to marry together the strengths of isotopic sediment tracer technology in the EU with ecological source apportionment models developed by North American scientists to deliver a powerful tool to combat threats to global food and water security. The tool will be showcased through its application in water-supply catchments where diffuse sediment and nutrient pollution from agriculture threatens food, water and, through siltation of of HEP dams, energy security.", "To": ["2017-06-30, closed project |"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2015-07-01"], "Project_ID": ["644320"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["UNIVERSITY OF PLYMOUTH"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Donating Robots a Theory of Mind"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["DoRoThy"], "Technology_Description": "This project aims to advance the science and technology of meta-cognition in social robotics. During social interactions, humans use powerful cognitive mechanisms to represent and interpret what others know or intend. Doing so helps us respond appropriately in social interactions: we use a combination of sensory perception together with internal models of what others are (and will be) doing and thinking. We believe these capabilities to be equally important for social robots, a type of robot which is intended to interact with people. Endowing robot with skills to \"read the minds\" of others is not only key to build next-generation assistive and industrial robots, but also presents a considerable research challenge. A challenge with tremendous benefits but few successes to date.", "To": ["2017-09-06, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-07"], "Project_ID": ["657227"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITY OF ESSEX"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Impacts of Nanoparticles on microphytobenthic Biofilms and consequences on the Carbon cycle"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["NanoBioCar"], "Technology_Description": "Intertidal and shallow subtidal zones are key areas for biochemical transformations, and particularly they play a crucial zone in the carbon cycle. In soft-bottom areas, most primary production is performed by photosynthetic microorganisms organised in biofilms, and called microphytobenthos. The organic matter they produce is rapidly respired by bacteria or consumed by higher trophic levels. Together, microphytobenthos and bacteria realise most carbon transformation in these areas, and are therefore important groups to study in a view to understand carbon cycling in coastal zones. Coastal areas are currently under influence of numerous stressors linked to anthropogenic effects. The impacts of \u2018well established\u2019 pollutants, e.g. metals, oils, nitrogen, are fairly well understood; however there is now evidence that new compounds, products of advanced technology, have the potential to disrupt the environment. The aim of this project is to understand how a recently developed family of compounds, namely nanoparticles (NPs), influences the development of biofilms and their impact on the carbon cycle. NP concentrations are increasing dramatically in the environment, but their effect on organisms and ecosystems is currently poorly described. Yet, genotoxic and cytotoxic effects of NPs have been demonstrated, including on microorganisms. In this project, laboratory and field experiments will be performed to characterise the effects of NPs on microphytobenthos and bacteria, on their trophic interactions and on their roles in carbon and nutrient cycles. Two common types of NPs will be tested in a wide range of environmental conditions, to decipher in which conditions NPs are more or less harmful to organisms and processes. Such understanding will allow developing strategies to reduce the impacts of NPs and will be beneficial to environment and human well-being in EU and elsewhere.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["702217"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE UNIVERSITY OF EXETER"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["PEATland modelling for global carbon cycle and climate models"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["PEATmod"], "Technology_Description": "Prediction of future climate change can only be achieved through models of the global climate system and its interactions with earth system processes. The reliability of the predictions depends on building the best understanding of these processes. Changes in the global carbon cycle are a source of major uncertainty in models and terrestrial carbon stored in peatlands is a critical element of this. The action proposed here will bring state-of-the-art process modelling into global vegetation models that are used in projections of future climate change. An improved understanding of peatland dynamics and functions will also have implications for management and climate mitigation strategies for wetlands, agriculture, land-use, and energy. I have worked extensively in North America on one of the most sophisticated peatland process models. I will work with Dan Charman and Angela Gallego-Sala at Exeter to build this model in to one of the most widely used dynamic global vegetation models so that peatlands and their carbon balance are better represented within global climate models. The work will thus allow quantification of the impact of peatlands on the global carbon cycle in the past and in the future. The action will bring top level expertise in peatland modelling back to Europe and build a bridge between the North American peatland modelling community and those in Europe. It will expose me to training and development in the necessary skills, people and laboratories to take this work forward independently in a European institution in the future. The supervisors at Exeter will develop their already strong record in carbon cycle and climate modelling and further develop links with other European workers and key groups in North America. Overall the action will provide a secure launch pad for my career, bring cutting edge skills to Europe and build stronger and long lasting linkages between European and North American science.", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["658041"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["CENTRO DE INVESTIGACION ECOLOGICA YAPLICACIONES FORESTALES CONSORCIO"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["A novel approach to determine canopy nitrification in the phyllosphere of European forests: combining multiple isotope tracers and proteogenomic techniques"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["NITRIPHYLL"], "Technology_Description": "Forest canopies play a significant role in regulating carbon and water exchanges with the atmosphere, with profound effects on our climate. However, their role in altering the chemical composition of precipitation and, consequently, the nutrient cycling within a forest has been less investigated. This is particular relevant for nitrogen (N)-limited forests in the Northern hemisphere, which have been exposed to a rapid human-induced increase in Ndep over the last decades. Much of the scientific attention has been focused on the role of Ndep in enhancing forest C-sink, while we still need to elucidate the fate of Ndep when entering forest and its contribution to N cycling. In particular, it is still not clear whether Ndep is retained, taken up and/or altered by biological transformations when interacting with tree canopies. By applying a quadruple isotope approach I recently demonstrated the occurrence of in-canopy biological nitrification of atmospheric N for UK forests at high Ndep. Hence, NITRIPHYLL intends to extend the multiple isotope approach a) to enlarge the range of conditions under which the process is demonstrated to occur, b) to investigate difference between species in the proportion of microbiologically-derived NO3 and c) the reasons of these differences. Furthermore, by using proteo-genomic techniques we aim to characterize phyllosphere microbial communities involved in canopy nitrification. We will consider i) forests along a gradient of climate and Ndep within the well established EU-ICP forest network and ii) existing N manipulation experiments. NITRIPHYLL for the first time merges two separate research avenues, i.e., the investigation of canopy nitrification with the study of the occurrence, abundance and diversity of bacteria communities in the phyllosphere. Thus, the project will contribute to providing a deeper understanding of how the phyllosphere affects the N, and consequently C, cycling within forests in relation to climate and Ndep.", "To": ["2018-06-05, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2016-06-06"], "Project_ID": ["705432"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITAET BASEL"], "EU_Contribution": ["EUR 187 419,60"], "Project_Title": ["Cold atom-semiconductor quantum interface"], "Total_Cost": ["EUR 187 419,60"], "Country": ["Switzerland"], "Project_ACR": ["3-5-FIRST"], "Technology_Description": "A group III/V semiconductor quantum dot will be interfaced with an ensemble of ultracold alkali atoms (first group). This interface will allow to combine efficient single photon generation in quantum dots with the excellent properties of cold atom quantum memories to build a key element for future high-speed quantum networks. ", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["702304"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITEIT TWENTE", "UNIVERSITEIT TWENTE"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Robot-Assisted Flexible Needle Steering for Targeted Delivery of Magnetic Agents"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["ROBOTAR"], "Technology_Description": "Diagnostic agents are currently injected into the body in an uncontrolled way and visualized using non-real-time imaging modalities. Delivering agents close to the organ and magnetically guiding them to the target would permit a myriad of novel diagnostic and therapeutic options, including on-site pathology and targeted drug delivery. Such an advance would truly revolutionize minimally invasive surgery (MIS). Presently MIS often involves manual percutaneous insertion of rigid needles. These needles deviate from their intended paths due to tissue deformation and physiological processes. Inaccurate needle placement may result in misdiagnosis or ineffective treatment. Thus, the goal of ROBOTAR is to design a robotic system to accurately steer flexible needles through tissue, and enable precise delivery of agents by magnetically guiding them to a designated target.", "To": ["2020-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-06-01"], "Project_ID": ["638428"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["UNIVERSITAET BASEL", "UNIVERSITAET BASEL"], "EU_Contribution": ["EUR 2 490 700"], "Project_Title": ["Directed Evolution of Artificial Metalloenzymes for In Vivo Applications"], "Total_Cost": ["EUR 2 490 700"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["DrEAM"], "Technology_Description": "In the past decade, artificial metalloenzymes (AMs) have emerged as an attractive alternative to the more traditional enzymes and homogeneous catalysts. Such hybrid catalysts result from the incorporation of an abiotic metal cofactor within a macromolecule (protein or oligonucleotide). Artificial metalloenzymes combine attractive features of both homogeneous catalysts and enzymes, including the possibility to genetically optimize the catalytic performance of new-to-nature organometallic reactions. Can artificial metalloenzymes become as catalytically efficient as naturally-evolved metalloenzymes, even in complex biological mixtures? Herein, we outline our efforts to address this challenge by localizing and evolving AMs within the periplasm of Escherichia coli. ", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["694424"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["UNIVERSITAET BASEL", "UNIVERSITAET BASEL", "FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION"], "EU_Contribution": ["EUR 2 499 250"], "Project_Title": ["Signal Transduction and Epigenetic Mechanisms of Breast Cell Plasticity and Cancer"], "Total_Cost": ["EUR 2 499 250"], "Country": ["Switzerland", "Switzerland", "Switzerland"], "Project_ACR": ["STEM-BCPC"], "Technology_Description": "Breast cancer is diagnosed in ~1.4 million women worldwide and ~500,000 lives are lost to the disease annually. Patients may do well after surgery and initial treatment, but drug resistant and fatal metastases often develop. Improved treatment options are urgently needed. The connecting thread of this project is the identification of epigenetic drivers of breast cell fate, tumor heterogeneity and metastasis.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2016-10-01"], "Project_ID": ["694033"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["UNIVERSITAET BASEL", "UNIVERSITAET BASEL"], "EU_Contribution": ["EUR 1 009 351"], "Project_Title": ["Fluid Flows and Irregular Transport"], "Total_Cost": ["EUR 1 009 351"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["FLIRT"], "Technology_Description": "Several important partial differential equations (PDEs) arising in the mathematical description of physical phenomena exhibit transport features: physical quantities are advected by velocity fields that drive the dynamics of the system. This is the case for instance for the Euler equation of fluid dynamics, for conservation laws, and for kinetic equations.", "To": ["2021-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["676675"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["UNIVERSITEIT TWENTE"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["A community of surface bots for creative storytelling"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["COBOTNITY"], "Technology_Description": "Interactive digital storytelling systems can be used to foster the development of creativity skills and enhance social awareness on our societal issues, aspects recognized to be strategic for our own future sustainability and competitiveness. However, current interactive storytelling approaches face important limitations in the implementation of digital characters. On the one hand, some systems provide very capable socially virtual agents used as characters, but enacted in a virtual world where technology is rather a barrier to effective creative thinking and collaboration. On the other hand, settings with tangible objects facilitate discussion in groups as well as the development of relevant critical social skills, but with characters unable to show advanced smart capabilities to enrich storytelling for a more effective process.", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["701991"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITY OF ESSEX", "UNIVERSITY OF ESSEX"], "EU_Contribution": ["EUR 2 499 471"], "Project_Title": ["Disagreements and Language Interpretation"], "Total_Cost": ["EUR 2 499 471"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["DALI"], "Technology_Description": "Natural language expressions are supposed to be unambiguous in context. Yet more and more examples of use of expressions that are ambiguous in context, yet felicitous and rhetorically unmarked, are emerging. In my own work, I demonstrated that ambiguity in anaphoric reference is ubiquitous, through the study of disagreements in annotation, that I pioneered in CL. Since then, additional cases of ambiguous anaphoric reference have been found; and similar findings have been made for other aspects of language interpretation, including wordsense disambiguation, and even part-of-speech tagging. Using the Phrase Detectives Game-With-A-Purpose to collect massive amounts of judgments online, we found that up to 30% of anaphoric expressions in our data are ambiguous. These findings raise a serious challenge for computational linguistics (CL), as assumptions about the existence of a single interpretation in context are built in the dominant methodology, that depends on a reliably annotated gold standard. ", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["695662"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["UNIVERSITY OF PLYMOUTH"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Neurophenomenology of Mental Imagery"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["NeuPheMi"], "Technology_Description": "The NeuPheMi project presents a novel approach in the neuroscientific study of mental imagery. Mechanisms of mental imagery are not yet well understood and while traditional approaches investigated their neural correlates based mostly on problem-solving tasks, NeuPheMi proposes to shed the light on the neural correlates of experiencing mental imagery. By taking into account the subjective experience and using electroencephalography and brain stimulation techniques to investigate the dynamic of neuronal activity during mental imagery in an original neurophenomenological approach, NeuPheMi is expected to bring a better understanding of the neuronal basis of mental imagery and extend our comprehension of human consciousness. ", "To": ["2018-03-21, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-03-22"], "Project_ID": ["660711"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["CENTRO DE INVESTIGACION ECOLOGICA YAPLICACIONES FORESTALES CONSORCIO"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Understanding soil fertility impacts on terrestrial biomass production in a changing environment"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["FIBER"], "Technology_Description": "The feedback between climate and the land carbon (C) cycle poses one of the largest uncertainties in climate change projections. FIBER targets the unresolved challenge for Dynamic Global Vegetation Models (DGVM) to simulate effects of soil fertility and nutrient deposition on biomass productivity (BP) and the land C balance. Accumulating evidence documents how plants adjust their growth strategies and C allocation under multiple limiting resources. Current DGVMs lag behind these new insights, produce widely diverging results for C cycling and nutrient limitation under future scenarios and fail to explain the observed land C sink. This work will provide a new global modelling approach to simulating flexible plant C allocation following optimality principles. A better understanding of the controls on BP is crucial for assessing climate change impacts on ecosystem services and to reduce uncertainty in C cycle and climate change projections.", "To": ["2019-02-27, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-02-28"], "Project_ID": ["701329"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITAET BASEL", "UNIVERSITAET BASEL"], "EU_Contribution": ["EUR 1 744 921"], "Project_Title": ["Holding hands: cell-cell junctions in breast cancer metastasis and resistance to therapy"], "Total_Cost": ["EUR 1 744 921"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["HOLDING-HANDS"], "Technology_Description": "Breast cancer is the most common cancer in women, resulting in as many as 500000 deaths per year worldwide. Patients with breast cancer die unequivocally because of the development of incurable distant metastases and not because of symptoms related to the primary site. Understanding the complex, yet fundamental mechanisms driving breast cancer metastasis is critical to develop therapies tailored to this disease.", "To": ["2021-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["678834"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["UNIVERSITAET BASEL", "UNIVERSITAET BASEL"], "EU_Contribution": ["EUR 2 499 500"], "Project_Title": ["Signal Integration by Gene Regulatory Landscapes"], "Total_Cost": ["EUR 2 499 500"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["INTEGRAL"], "Technology_Description": "Identification of the molecular mechanisms by which gene regulatory landscapes integrate diverse signaling inputs into a robust and dynamic transcriptional output is key to a comprehensive mechanistic understanding of the systems that govern vertebrate organogenesis. We will tackle this by taking advantage of our in-depth knowledge of the self-regulatory signaling systems controlling vertebrate limb development. To capture the dynamics by which the major signaling pathways (BMP, SHH, WNT, FGF) interact to control gene expression, we will profile chromatin architecture, epigenetic marks and the interaction kinetics of transcriptional effectors with cis-regulatory modules (CRMs) during mouse limb bud development. First, we will focus on the Grem1 gene regulatory landscape, as this BMP antagonist is a key node in the system and its spatio-temporal expression is regulated by all four pathways. This analysis will capture the temporal activity of all CRMs in the Grem1 landscape and reveal the ones that are targets of one or several signaling pathways. The functional requirements of single and multiple CRMs with redundant functions will be assessed by gain- and loss-of-function genetics in mice. This analysis together with in silico simulations of the relevant interactions aims to reveal the underlying regulatory logic. Second, the genome-wide datasets will be used to analyse the gene regulatory landscapes of signals involved in epithelial-mesenchymal and auto-regulatory feedbacks. Third, the trans-cis regulatory alterations underlying the evolutionary diversifications that resulted in digit loss and reductions will be functionally studied by comparative analysis of mouse, bovine, pig and chicken limb buds. Finally, as aberrant Grem1 expression predisposes to various diseases and cancers, we will study the trans-cis regulatory alterations that affect the Grem1 landscape in a mouse model of SHH-induced cerebellar medulloblastomas, which depends on aberrant Grem1 expression.", "To": ["2021-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-08-01"], "Project_ID": ["695032"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["UNIVERSITEIT TWENTE", "UNIVERSITEIT TWENTE"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Information-age microscopy for deep vision imaging of biological tissue"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["DEEPVISION"], "Technology_Description": "Modern biology could not exist without the optical microscope. Hundreds of years of research have seemingly developed microscopes to perfection, with one essential limitation: in turbid biological tissue, not even the most advanced microscope can penetrate deeper than a fraction of a millimetre. At larger depths light scattering prevents the formation of an image. DEEP VISION takes a radically new approach to microscopy in order to lift this final limitation.", "To": ["2021-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["678919"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["ARISTOTELIO PANEPISTIMIO THESSALONIKIS", "ARISTOTELIO PANEPISTIMIO THESSALONIKIS", "UNIVERSITAET BASEL", "UNIVERSITAET HOHENHEIM", "UNIVERSITAT WIEN", "OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN"], "EU_Contribution": ["EUR 1 891 875"], "Project_Title": ["Identifying the food cultures of ancient Europe: an interdisciplinary investigation of plant ingredients, culinary transformation and evolution through time"], "Total_Cost": ["EUR 1 891 875"], "Country": ["Greece", "Greece", "Switzerland", "Germany", "Austria", "Austria"], "Project_ACR": ["PLANTCULT"], "Technology_Description": "The project seeks to explore culinary practice among early farming European communities, from the Aegean to Central Europe, spanning the Neolithic through to the Iron Age (7th-1st millennia BC). The project seeks to identify the \u2018food cultures\u2019 of prehistoric Europe, and to reconstruct how cultivated and wild plant foods were transformed into dishes exploring their underlying cultural and environmental contexts and their evolution through time. The project will explore how culinary identities were shaped through the selection of plant foods both in terms of ingredients as well as processing and cooking practices. Thus not only species and meals but also the equipment involved in plant food preparation will be considered for the study area, linking the end product to the relevant technologies of transformation. Macroscopic and microscopic examination of the archaeological finds and experimental replication of various aspects of food preparation techniques informed by ethnographic investigations will form the main analytical tools. The interdisciplinary and contextual examination of the archaeological record will provide a fresh insight into prehistoric cuisine in Europe, the transformation of nature to culture through cooking. The project will revolutionise perceptions of prehistoric food preparation providing insights for the \u2018longue dur\u00e9e\u2019 of traditional plant foods constituting Europe\u2019s intangible cultural heritage.", "To": ["2021-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Greece"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2016-04-01"], "Project_ID": ["682529"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["UNIVERSITEIT TWENTE", "UNIVERSITEIT TWENTE"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["NanoPacks: Assembling nanoparticles via evaporation-driven droplet collapse for ultrasensitive detection techniques"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["NanoPacks"], "Technology_Description": "The foundation of nanophotonics and nanoplasmonics has boosted the development of ultrasensitive detection techniques. Some of these techniques, such as Surface Enhanced Raman Spectroscopy or Surface Enhanced Fluorescence, are able to detect femtomolar concentrations of analytes or even single molecules, only relying on the adsorption of the analytes on a nanostructured surfaces. ", "To": ["2021-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-08-01"], "Project_ID": ["678573"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["CARDIFF METROPOLITAN UNIVERSITY"], "EU_Contribution": ["EUR 251 857,80"], "Project_Title": ["Understanding blood pressure and vascular haemodynamics in implanted Left Ventricular Assist Device patients."], "Total_Cost": ["EUR 251 857,80"], "Country": ["United Kingdom"], "Project_ACR": ["HIT-LVAD"], "Technology_Description": "Background: Advanced heart failure (HF) is a growing health problem in the European Union (EU). Consequently, a growing number of HF patients now depend on state-of-the-art continuous flow Left Ventricular Assist Devices (cf-LVAD) as a bridge to transplant or as a means of destination therapy. Since the introduction and usage of cf-LVAD\u2019s rather than traditional pulsatile LVAD\u2019s, survival rates have significantly improved. However, an increased number of side-effects, including stroke and microvascular bleeding, have been reported. Suggested mechanisms associated with these side effects is lack of pulsatile pressure and flow throughout the system, however there are currently no data on macro/micro haemodynamics in these patients.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["705219"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITEIT TWENTE", "UNIVERSITEIT TWENTE"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Rare earth doped novel on-chip sources"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["RENOS"], "Technology_Description": "The development of compact, low cost, power efficient, tunable lasers and frequency combs spanning large bandwidths, exhibiting excellent output beam characteristics, such as the ones achieved in solid-state sources, and expanding the wavelength ranges of by typical solid-state materials, will greatly benefit application fields such as optical sensing, spectroscopy, metrology and telecommunications.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["648978"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["CENTRO DE INVESTIGACION ECOLOGICA YAPLICACIONES FORESTALES CONSORCIO"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Hydraulic functional traits as determinants of forest function and drought responses. Putting xylem and phloem attributes into the functional trait map."], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["PHLOEMAP"], "Technology_Description": "Forests provide key ecological services such as the regulation of energy, carbon and water balances from local to global scale. These are however under severe pressure due to climate and land use changes, especially in the Mediterranean basin where limited water availability is prominent. It is thus crucial to identify the forest species and areas that are likely to be more vulnerable to reduced water availability and establish how changes in forest composition and structure will impact key ecosystem services. In this project, we will use the functional trait concept to bridge between tree, population, species and forest level and as such enlarge our capacity to predict where and when dramatic changes in forest ecosystem services are likely to occur, especially focusing on the role of phloem and parenchyma tissue in tree and forest functioning in relation to drought. Our objectives are to (i) measure phloem and parenchyma traits of 104 populations of 7 dominant tree species in Catalonia and Portugal, study the relationships between these traits and other hydraulic and functional traits and quantify their variability along gradients in water availability, (ii) integrate phloem and parenchyma traits in the theoretical framework describing tree responses to drought, (iii) determine which combination of traits is the best predictor of drought resistance at intra- and interspecific level and (iv) test how and to which extent variability in phloem and parenchyma traits influences forest performance at different ecological scales and forest vulnerability under climate change scenarios. Classical wood anatomy and plant physiology methods will be used as well as novel 3D techniques and recently developed models will be combined and extended. Our results will contribute to the knowledge needed to design effective strategies to deal with climate change. Transferring it to managers and policy makers, as well as to the society at large, is thus a focus of the proposal.", "To": ["2018-01-14, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2016-01-15"], "Project_ID": ["659191"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE UNIVERSITY OF SHEFFIELD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "HELIA PHOTONICS LTD", "TECHNISCHE UNIVERSITAET MUENCHEN", "UNIVERSITAT KONSTANZ", "ATTOCUBE SYSTEMS AG", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "TECHNISCHE UNIVERSITEIT DELFT", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "UNIVERSITAET BASEL", "KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 3 965 414,04"], "Project_Title": ["Nanoscale solid-state spin systems in emerging quantum technologies"], "Total_Cost": ["EUR 3 965 414,04"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom", "Germany", "Germany", "Germany", "France", "Netherlands", "Switzerland", "Switzerland", "Denmark"], "Project_ACR": ["Spin-NANO"], "Technology_Description": "This network brings together world-leading experts in nano-science and technology from 6 European countries in order to achieve breakthroughs in understanding and successful utilization of nanoscale solid-state spin systems in emerging quantum technologies. The proposed innovative science in the supra-disciplinary field of physics and applications of spin nano-systems will underpin breakthrough developments in quantum computing, quantum communications and networks, and nano-imaging. Important innovative step consolidating the joint effort of the whole consortium is the focus on crystalline solids where magnetic interactions of electron spins with lattice nuclei are negligible and well-controlled. We will develop electrically-controlled spin-quantum-bits (qubits) in Si-Ge quantum dots and nanowires; will optically manipulate spin impurities in diamond in applications for quantum computing and networks and in nano-magnetometry; will achieve new understanding of quantum phenomena due to the spin-valley coupling in atomically thin 2D semiconductors, an emerging class of materials with a promise for quantum technologies. Research training to 15 early stage researchers will be delivered by 14 academic and 7 industrial groups. Network-wide training course in transferable skills will be specially developed and delivered by the Think Ahead (Sheffield), an award winning initiative at the University of Sheffield (award by the Times Higher Education, 2014). Current proposal is designed to advance this multi-disciplinary research field significantly beyond the state-of-the-art, and train a new cohort of researchers capable of developing spin-based solid-state quantum technologies towards real-life applications in the next 5 to 10 years.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["676108"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["UNIVERSITEIT TWENTE", "UNIVERSITEIT TWENTE"], "EU_Contribution": ["EUR 2 250 000"], "Project_Title": ["Vascular Engineering on chip using differentiated Stem Cells"], "Total_Cost": ["EUR 2 250 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["VESCEL"], "Technology_Description": "Organs-on-chip hold great promise for the creation of complex and realistic disease models while having the potential to refine, reduce and (partly) replace existing animal models (3R principle). Of all organs, vasculature is extremely well-suited to realize on-chip since it pervades the whole organism, is present in all other organs, its malfunctioning plays a role in many diseases and finally is ideally suited to approach with microfabrication and microfluidic technologies. In the VESCEL program we propose the development of innovative technologies enabling the use of differentiated human induced pluripotent stem cells (hiPSC) to engineer blood vessels on chip that constitute realistic disease models for thrombosis and neurodegenerative (ND) diseases. The use of differentiated hiPSC allows the realization of blood vessels based upon patient-specific material, without the need for biopsies, while development of integrated microsensors for small molecules (pH, O2, NO) offers the possibility of on-line monitoring. To optimize the hiPSC differentiation conditions we propose the use of a microdroplet platform, that combines high-throughput capability (up to 1000 cells/s) with control of single cell microenvironment. We will also develop a new flexible technology for real 3D vasculature realization using advanced 3D printing technologies. These four innovative technology developments will be integrated in two biomedical applications to study two important classes of diseases, thrombosis and neurodegenerative (ND) diseases. For thrombosis we focus on the study of parameters such as blood pressure and stenosis as well as effects of drugs on thrombus formation, while for ND diseases study we will use a blood brain barrier (BBB) model to investigate nanoparticle and peptide transport across the BBB for a form of Alzheimer\u2019s disease, as well as leukocyte extravasation for multiple sclerosis (MS).", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["669768"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["UNIVERSITY OF PLYMOUTH", "SOFTBANK ROBOTICS EUROPE"], "EU_Contribution": ["EUR 1 345 614,84"], "Project_Title": ["Applications of Personal Robotics for Interaction and Learning"], "Total_Cost": ["EUR 1 345 614,84"], "Country": ["United Kingdom", "France"], "Project_ACR": ["APRIL"], "Technology_Description": "The aim of personal robotics is to design companion robots that can live and interact with people in a very intuitive way. This requires designing robots that are capable of adapting to the human users, via learning during interaction. This proposal aims at the timely establishment of the first European Industrial Doctorate in \u201cApplications of Personal Robotics for Interaction and Learning\u201d (APRIL) to train future researchers and engineers for the emerging field of personal robotics. APRIL strategically adopts a key entrepreneurial ethos which will equip PhD students with radical cross-sector and interdisciplinary skills and mind-set, by combing research on developmental and social cognitive systems with hands-on experiments on the application of human-robot interaction and assistive systems. APRIL is the result of the strategic synergies of Plymouth University Centre for Robotics and Neural Systems with its international leadership and reputation as UK and European hub in cognitive developmental robotics and human-robot interaction, and with Aldebaran Robotics A-Lab R&D Division which has the world leading market position in the personal robotics industry with the robots NAO and Pepper. This is complemented by six international partners from industry (SONY Corporation, MetraLabs GmbH), academia (Osaka, Humboldt Berlin) and robot users (San Raffaele Hospital Milan and SSSA DomoCasa Pisa). The doctoral training strategy of the EID will implement the latest innovative PhD training approaches of situative and social constructivist learning theories with a unique Coaching Programme for a tailored Individual Skills Development Plan, peer-support and student-centred cohort activities, as well as a strong leadership skills programme for continuous professional development. The two beneficiaries will contribute with a pool of over 12 academic and industry supervisors and will fund 5 additional PhD bursaries to match the EID cohort of the 5 Marie Sk\u0142odowska-Curie funded ESR", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-EID - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-EID)"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-01-01"], "Project_ID": ["674868"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["STICHTING IHE DELFT"], "EU_Contribution": ["EUR 190 862,10"], "Project_Title": ["Visualizing aquifers: sustainable water use in the Atacama Desert and beyond"], "Total_Cost": ["EUR 190 862,10"], "Country": ["Netherlands"], "Project_ACR": ["INVISIBLE WATERS"], "Technology_Description": "Billions of people rely for their everyday existence on aquifers. The invisibility of these waters, however, poses formidable challenges for those who rely on them: locating, measuring and controlling aquifers is complex and precarious, yet of utmost importance for human survival in many parts of the world. The overall aim of the proposed project is to explore the vital connections between humans and aquifers in everyday life. Building on trans-disciplinary studies that consider water as the contested nexus of social and political affairs, this project explores groundwater as both mediating and generating diverse \u2018groundwater practices\u2019: as an invisible resource, groundwater requires visualization; as an underground supply, it calls for innovative extractive techniques; as a finite good, groundwater needs to be regulated and controlled; and as a practical everyday resource, it sustains irrigation, sanitation, and human consumption. Through ethnographic fieldwork in Atacama Desert of Northern Chile, this project will develop an analytical framework to understand how social relations are affected by various groundwater practices. The proposed research will explore such practices with a focus on the effects that the visualization of aquifers has on socio-economic and eco-political inequalities. Through transdisciplinary training at the Universidad Cat\u00f3lica del Norte, I will strengthen methodological skills to study the groundwater practices of indigenous communities, hydro-geologists and state administrators. I will transfer the acquired skills to the UNESCO-IHE Institute for Water Education, where I will strengthen understandings of the dynamics among groundwater practices, power, and culture, providing trans-disciplinary input for policymakers engaged in the design and realization of the Sustainable Development Goals. Findings will be disseminated among policymakers, academics, and broader audiences concerned with environmental sustainability.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Netherlands"], "Activity": ["Research Organisations"], "From": ["2017-01-01"], "Project_ID": ["706346"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITAET BASEL", "UNIVERSITAET BASEL"], "EU_Contribution": ["EUR 2 496 460"], "Project_Title": ["Alternative Splicing Codes for Synaptic Specificity"], "Total_Cost": ["EUR 2 496 460"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["SPLICECODE"], "Technology_Description": "Neuronal networks represent an impressive example of highly organized complex systems. Sperry postulated that selective neuronal connectivity is achieved by chemoaffinity labels. Several such labels for axon guidance and topographic mapping have been defined. However, until recently, molecules that direct the recognition of synaptic partners and functional specification of synapses have remained obscure.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["694584"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["CHALMERS TEKNISKA HOEGSKOLA AB", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSITAET BASEL", "AKADEMIA GORNICZO-HUTNICZA IM. STANISLAWA STASZICA W KRAKOWIE", "THE HEBREW UNIVERSITY OF JERUSALEM", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "TECHNISCHE UNIVERSITAET DRESDEN", "RUDER BOSKOVIC INSTITUTE", "EIDGENOSSISCHE MATERIALPRUFUNGS- UND FORSCHUNGSANSTALT"], "EU_Contribution": ["EUR 4 193 147,25"], "Project_Title": ["Reservoir Computing with Real-time Data for future IT"], "Total_Cost": ["EUR 4 193 147,50"], "Country": ["Sweden", "France", "Switzerland", "Poland", "Israel", "France", "Germany", "Croatia", "Switzerland"], "Project_ACR": ["RECORD-IT"], "Technology_Description": "The aim of this proposal is to develop an intelligent biocompatible sensing device which detects complex behavioural changes in ion concentrations. The sensor will use wet NOMFETs, coated Si nanowires, self-conjugated polymers, arrays of photocells, flow of lipids. The level of ions will be measured by monitoring changes in the response function of the system. The high sensitivity of the device will be achieved by ensuring a strong coupling between the environment and the device. The key research challenges will be: accessing the feasibility of the idea to use reservoir computing for sensing complex environmental changes, identifying suitable integration strategies for the components, optimizing the sets of input/output pairs (response functions) and the device components for enhanced sensitivity.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-1-2014 - FET-Open research projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["664786"], "Call_for_Proposal": ["H2020-FETOPEN-2014-2015-RIA"]}, -{"Partners": ["UNIVERSITY OF EAST ANGLIA", "UNIVERSITAT DE LES ILLES BALEARS", "AARHUS UNIVERSITET", "UNIVERSITY OF PLYMOUTH", "FRIEDRICH-SCHILLER-UNIVERSITAT JENA", "NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU", "QUALISYS AB", "WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER", "CONSIGLIO NAZIONALE DELLE RICERCHE", "DANIELI TELEROBOT LABS S.R.L.", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich"], "EU_Contribution": ["EUR 3 460 823,28"], "Project_Title": ["Deictic Communication - A Multidisciplinary Training"], "Total_Cost": ["EUR 3 460 823,28"], "Country": ["United Kingdom", "Spain", "Denmark", "United Kingdom", "Germany", "Norway", "Sweden", "Germany", "Italy", "Italy", "Switzerland"], "Project_ACR": ["DCOMM"], "Technology_Description": "Deictic communication is fundamental to understanding communication in both typical and atypical populations, and forms the key connection between language and objects/locations in the world. It is therefore critical to understanding human-human interaction, and human-system interaction in a range of technology applications \u2013 from mobile phones to cognitive robotics \u2013 and to the enhancement of clinical and educational interventions with typical and atypical populations. This ETN will train the next generation of scientists in the full range of multidisciplinary and cross-sectorial methods necessary to make significant progress in understanding deictic communication, with direct synergies between basic research and application. Training is structured around two interdisciplinary research themes \u2013 Understanding Deictic Communication and Deictic Communication in Application \u2013 both involving extensive and systematic co-supervision and collaboration across sites with key interplay between academic and nonacademic beneficiaries and partners. In turn we expect that a range of applications will be enhanced with increased usability, with associated societal and economic benefit. The training of the cohort of ESR fellows is based on innovative PhD training approaches, providing not only training in interdisciplinary methods, but also employing peer-assisted methods and the latest in educational innovation. This will produce a cohort of highly skilled researchers who will be highly employable given the potential contribution they will make to future research and innovation in the public and private sectors.", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2016-02-01"], "Project_ID": ["676063"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["Fundaci\u00f3 Institut d'Investigaci\u00f3 Biom\u00e8dica de Bellvitge", "UNIVERSITY COLLEGE LONDON", "FORSCHUNGSVERBUND BERLIN EV", "THE BABRAHAM INSTITUTE", "INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE", "CENTRE EUROPEEN DE RECHERCHE EN BIOLOGIE ET MEDECINE", "FUNDACIO PRIVADA INSTITUT D'INVESTIGACIO ONCOLOGICA DE VALL-HEBRON", "UNIVERSITA DEGLI STUDI DI TORINO", "UNIVERSITAET BASEL", "ARIVIS AG"], "EU_Contribution": ["EUR 3 896 334,72"], "Project_Title": ["Deciphering PI3K biology in health and disease"], "Total_Cost": ["EUR 3 896 334,72"], "Country": ["Spain", "United Kingdom", "Germany", "United Kingdom", "France", "France", "Spain", "Italy", "Switzerland", "Germany"], "Project_ACR": ["Phd"], "Technology_Description": "The Phosphoinositide 3-kinase (PI3K) pathway is at the core of multiple fundamental biological processes controlling metabolism, protein synthesis, cell growth, survival, and migration. This inevitably leads to the involvement of the PI3K signalling pathway in a number of different diseases, ranging from inflammation and diabetes to cancer, with PI3K pathway alterations present in almost 80% of human cancers. Therefore, PI3Ks have emerged as important targets for drug discovery and, during 2014, the first PI3K inhibitor was approved by FDA in the US for the treatment of a lymphocytic leukaemia. Nonetheless, our understanding of PI3K-mediated signalling is still poor and only a fraction of the potential therapeutic applications have been addressed so far, leaving a large amount of translational work unexplored. Europe features a set of top quality research institutions and pharmaceutical companies focused on PI3K studies but their activities have been so far scattered. This proposal fills this gap by providing a multidisciplinary network (biochemistry, mouse studies, disease models, drug development, software development) and an unprecedented training opportunity from the bench to the bedside (from pre-clinical discoveries to clinical trials), through cutting edge molecular biology, drug discovery and clinical trial organization. The proposal is aimed at training young investigators in deep understanding of the different PI3K isoforms in distinct tissues and to translate this knowledge into a new generation of PI3K inhibitors, treatment modalities and into identify new uses for existing PI3K inhibitors.", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-11-01"], "Project_ID": ["675392"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["UNIVERSITEIT TWENTE", "UNIVERSITEIT TWENTE"], "EU_Contribution": ["EUR 149 578,75"], "Project_Title": ["Hypermethylated DNA detection using NanoGaps"], "Total_Cost": ["EUR 149 578,75"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["HYMEDNA"], "Technology_Description": "HYMEDNA prepares commercialization of very sensitive point-of-care biosensors for early-stage cancer detection based on the electrical detection of hypermethylated DNA (hmDNA) inside nanogaps.", "To": ["2016-09-30, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2014 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["665651"], "Call_for_Proposal": ["ERC-2014-PoC"]}, -{"Partners": ["UNIVERSITEIT TWENTE", "UNIVERSITEIT TWENTE"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Explore the potentialities of biostealth coatings for tissue engineering and reconstructive medicine"], "Total_Cost": ["EUR 150 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["BioStealth"], "Technology_Description": "BioStealth production of implant coatings provides an exciting business opportunity. BioStealth offers unique advantages of societal and economic importance, such as public health and sick leave. ", "To": ["2016-07-31, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2014 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-02-01"], "Project_ID": ["641342"], "Call_for_Proposal": ["ERC-2014-PoC"]}, -{"Partners": ["UNIVERSITY OF PLYMOUTH"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Paleozoic Seafloor Spreading"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["PASS"], "Technology_Description": "It is now recognised that large oceanic detachment faults are fundamentally important along slow-spreading rate portions of the mid-ocean ridge system. These fault systems have been the target of numerous scientific expeditions leading to a new paradigm of \u201cdetachment-mode\u201d spreading. However, in the modern oceans this style of spreading can only be documented back to 10-12 Ma. To understand these systems in the deep geological past it is necessary to work on ancient examples of detachment faults in ophiolites, slices of oceanic lithosphere that have been emplaced tectonically onto continental margins and which expose ocean floor structures in 3-D. Recent work in the Mirdita ophiolite of Albania has demonstrated that detachment-mode spreading operated in the Jurassic period. This project will extend this record back to the Palaeozoic, by investigating a detachment system preserved in the Thetford Mines Ophiolite of Canada. An integrated field-based structural and palaeomagnetic investigation will test the hypothesis that this example provides the oldest known analogue for modern oceanic detachment systems. Objectives are to: (i) systematically back-strip successive tectonic events that have affected the ophiolite, in order to recover primary seafloor relationships; (ii) determine whether relative tectonic rotation has occurred across the detachment fault, a defining feature of modern examples; and (iii) quantify the role of large- and small-scale faulting in accommodating displacement within the detachment system. The project will provide: (i) extensive training in field-based tectonic applications of palaeomagnetism, directly complementing the Fellow\u2019s existing expertise and experience in laboratory techniques, thereby allowing her to conduct future investigations in complex tectonic environments; and (ii) engagement with the international oceanic scientific community, opening future opportunities to move into oceanic geodynamic research.", "To": ["2017-09-03, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-04"], "Project_ID": ["660362"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["CENTRO DE INVESTIGACION ECOLOGICA YAPLICACIONES FORESTALES CONSORCIO"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Remote sensing INdicators for DROught monitoring"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["INDRO"], "Technology_Description": "Droughts affect most parts of the world. According to the recent previsions of the Intergovernmental Panel on Climate Change1 (IPCC), more frequent and severe droughts are expected. This observation makes it a priority to improve the existing methods of monitoring droughts and their impact on terrestrial ecosystems. Early warning systems need to be developed. Remote sensing (RS) technologies are well-placed to provide such monitoring. Thanks to RS, droughts can be monitored at large scale and at short time resolution (e.g., daily). The proposed project \u201cINDRO\u201d will focus on the definition of new RS-based indicators able to monitor vegetation status and how it is responding to drought. For example, the RS indicators implemented at the moment within the European Drought Observatory (EDO) early monitor system are not sensitive to rapid changes in plant photosynthesis since these indicators have no direct link to plant photosynthetic functioning. The project will analyse the relationships between ecophysiological variables, light use activity (LUE) and existing RS indicators calculated with the data from several satellite sensors. This analysis will reveal which sensors, and which spatial and temporal resolutions are best at quantifying drought. A new generation of RS indicators will be developed to give a better description of plant photosynthetic functioning in drought conditions. The project will map these new indicators for southern Europe to identify the areas affected by drought. Overall, the creation of new RS drought indicators, and the better definition of drought events they bring, will help the development of ecological models and early warning systems, and underpin new avenues for the improvement of national and international drought mitigation and adaptation strategies.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-05-01"], "Project_ID": ["702717"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITY OF PLYMOUTH"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Fundamental physics with intense laser fields"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SF-QFT"], "Technology_Description": "High-intensity lasers have the potential to offer groundbreaking insights into physics both within and beyond the Standard Model, as well as a wealth of applications in science, medicine, technology and industry. There is therefore an international drive to explore fundamental physics in intense laser fields, in the regime where both relativistic and quantum effects are significant.", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["701676"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITEIT TWENTE", "UNIVERSITEIT TWENTE"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["On-Chip Cytometry Printed On Demand"], "Total_Cost": ["EUR 150 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["CyPod"], "Technology_Description": "Cytometry (the characterisation and counting of cells) is essential to clinical diagnostics, biotechnology, food industry, water monitoring and many fields of research. Within the ERC Starting Grant, InstantCount, inkjet printing methods have been developed, which allow us to fabricate cell counting chambers with on-chip sample preparation, simplifying cell counting procedures tremendously. By effectively eliminating all sample preparation steps and efficient usage of reagents CyPod promises low-cost, simple, rapid cell counting, including mobile applications. The fabrication by inkjet printing enables us to offer tailor-made solutions. We expect that CyPod tests can replace expensive and complex instruments in many existing cell counting applications, as well as open new markets, e.g. in agriculture and food industry. This project aims at evaluating and enhancing the competitiveness of CyPod cell counting technology by analysing the market, comparing CyPod with potential competitors and adapting our concept to identified customers\u2019 needs. A product demonstration for potential customers and partners will be prepared and the optimal business strategy will be selected for which a business plan will be devised.", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2015 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["694045"], "Call_for_Proposal": ["ERC-2015-PoC"]}, -{"Partners": ["UNIVERSITY OF PLYMOUTH"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Sediment linkage between land, river and sea: evaluating impacts of historic mining on sediment quality in the coastal zone"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SEDiLINK"], "Technology_Description": "Monitoring datasets available to evaluate past mining impacts on catchment and coastal environmental quality are severely limited in temporal extent presenting a major hindrance to effective decision making for management of legacy pollution to achieve the goals of the EU Water Framework Directive and Mining Waste Directive. The \u201cSediment linkage between land, river and sea: evaluating impacts of historic mining on sediment quality in the coastal zone\u201d (SEDiLINK) research project will develop an innovative sedimentological approach to overcome these important challenges and close this substantial knowledge gap. The SEDiLINK approach will bring together established techniques (e.g. Pb-210 geochronology) with new approaches in evaluating riverine ecosystems (e.g. Pb isotope fingerprint) and deliver an integrated toolkit for evaluation of mine waste impacts. The extensive metal mining history of Tamar River Basin and coastal zone, southwest UK, offers an ideal test-bed in which to develop the novel and powerful SEDiLINK approach for wider application in other EU contaminated fluvial and coastal ecosystems requiring longer term remediation legacy pollution.", "To": ["2017-06-30, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-07-01"], "Project_ID": ["658863"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITY OF PLYMOUTH"], "EU_Contribution": ["EUR 251 857,80"], "Project_Title": ["Inclusive Education for an Inclusive Europe: Examining Social Interactions, Dynamics and Friendship Networks of Students in Mainstream Primary Schools"], "Total_Cost": ["EUR 251 857,80"], "Country": ["United Kingdom"], "Project_ACR": ["IE2"], "Technology_Description": "The overarching research aim of this project is to examine the social interactions, dynamics and friendship networks of all students, with an emphasis on those identified as having special educational needs, in mainstream primary schools. The IE2 project strives to understand how inclusive education is being implemented across three countries (US, UK, Cyprus) and contribute to the debate on how to create a more inclusive European society by providing rigorous research evidence and recommendations. The project sets out to achieve three main objectives. First, to develop an innovative and interdisciplinary methodology to understand the social interactions, peer relationships and friendships with the combination of advanced social network analysis and ethnographic methods. Second, to establish a social network analysis toolkit for schools to enable practitioners understand the social dynamics within their settings. Third, to develop a platform for visualizing large datasets within social sciences and humanities. It is anticipated that the project will generate a significant impact on both the educational and social sciences and the researcher in terms of reaching a higher position of professional maturity. This is a project that is innovative and interdisciplinary as it breaks the boundaries between social sciences and humanities and computational studies, mathematics and statistics.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["660607"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["EUROPEAN SUSTAINABLE ENERGY INNOVATION ALLIANCE - ESEIA, VEREIN FUR FORDERUNG DER EUROPAIESCHEN INNOVATION FUR ERNEUERBARE ENERGIEN", "BRP-POWERTRAIN GMBH & CO KG", "ENERGIE AGENTUR STEIERMARK GEMEINNUTZIGE GMBH", "TECHNISCHE UNIVERSITAET GRAZ", "UNIVERSITE DE LIEGE", "UNIVERSITY OF ZAGREB - FACULTY OF FOOD TECHNOLOGY AND BIOTECHNOLOGY - UZAG PBF", "SVEUCILISTE U ZAGREBU, FAKULTET STROJARSTVA I BRODOGRADNJE", "LAPPEENRANNAN TEKNILLINEN YLIOPISTO", "INSTITUT POLYTECHNIQUE DE GRENOBLE", "BERGISCHER ABFALLWIRTSCHAFTSVERBAND", "UNIVERSITEIT TWENTE", "Laboratorio Nacional de Energia e Geologia I.P.", "TORRES & BELO SA", "\"ASOCIATIA \"\"GREEN ENERGY\"\"\""], "EU_Contribution": ["EUR 1 377 000"], "Project_Title": ["People for tHe eurOpean bioENergy mIX"], "Total_Cost": ["EUR 1 377 000"], "Country": ["Austria", "Austria", "Austria", "Austria", "Belgium", "Croatia", "Croatia", "Finland", "France", "Germany", "Netherlands", "Portugal", "Portugal", "Romania"], "Project_ACR": ["Phoenix"], "Technology_Description": "The development and adoption of renewable and sustainable forms of energy has become a major priority for Europe and is an important theme in H2020. Research into new, energy-related technologies to reduce Europe\u2019s reliance on non-renewable fossil fuels is a critical need, and requires more newly qualified people in areas such as renewable-energy infrastructure management, new energy materials and methods, as well as smart buildings and transport. Bio-energy is particularly relevant to the Work Programme, because it is at the crossroads of several key European policies \u2013 from the Strategic Energy Technology Plan Roadmap on Education and Training (SET-Plan) to the European Bio-economy Strategy for European Food Safety and Nutrition Policy. So far, technological development has concentrated on using crops and wood for fuel, energy and industrial products. These conventional bio-resources are, however, limited, and the use of nonconventional, currently unused or under-utilised bio-resources provides the best possibility for the growth of the bioeconomy. However, European development in this priority field is failing to keep pace with demand due to a lack of qualified personnel, a lack of cohesion and integration among stakeholders, and poorly developed links between professional training and the real needs of industry. Based on seven work packages the Phoenix RISE project will address these issues by exploiting the complementary expertise of its partners and creating synergies between them through the targeted secondments of staff to advance research and innovation knowledge in bio-energy research. Phoenix is an international, interdisciplinary, cross-sectorial project, bringing together a total of 16 partners: 14 from the EU (5 companies and 9 academic organisations) and two Third-Country academic partners to enhance its collective research excellence and create new, post-graduate-level research training in key disciplines that support the provision of bio-energy.", "To": ["2019-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Austria"], "Activity": ["Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other"], "From": ["2015-12-01"], "Project_ID": ["690925"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["UNIVERSITY OF PLYMOUTH", "LIVERPOOL JOHN MOORES UNIVERSITY", "NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA"], "EU_Contribution": ["EUR 517 500"], "Project_Title": ["Partnership for Research in Geopolymer Concretes"], "Total_Cost": ["EUR 517 500"], "Country": ["United Kingdom", "United Kingdom", "Greece"], "Project_ACR": ["PRIGeoC"], "Technology_Description": "Concrete, owing to its availability, easy preparation and fabrication, is the most popular construction material. However, the cement industry is facing unprecedented challenges caused by energy resources and CO2 emissions. Despite the incremental improvements in process efficiency adopted by the cement industry in recent years, OPC production is still responsible for around 6% of all man-made global carbon emissions. The proposed project aims to develop green concretes by using novel geopolymer materials as new binder and recycled concrete as part of the aggregates. The geopolymer is a type of amorphous alumina-silicate products. It can be synthesized by poly-condensation reaction of geopolymetric precursor and alkali polysilicates, which are available in natural materials or from industrial by-products. Geopolymer materials represent an innovative technology that is generating considerable interest in the construction industry, particularly in light of the ongoing emphasis on sustainability. However, although numerous geopolymer systems have been proposed, most are difficult to work with and require great care in their mixing process. Furthermore, the lack of long-term performance and durability data is also a barrier to the acceptance and widespread commercial use of geopolymer concretes in the construction industry. The proposed research will cover not only the finding of novel geopolymers but also provide long-term performance and durability data for geopolymer concretes used in different environments. The research outcome will have a great impact on our understanding of how geopolymer concretes perform in different environments and how their mechanical properties and performance can be improved by using correct mixing processes. The research will also provide vital information on how to revolutionise the production of concrete materials and how to engineer concrete binders using different geopolymers to tailor the properties of the resulting concrete.", "To": ["2020-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["689857"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI PADOVA", "TECHNISCHE UNIVERSITEIT EINDHOVEN", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "UNIVERSITEIT TWENTE", "FREIE UNIVERSITAET BERLIN", "WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER"], "EU_Contribution": ["EUR 2 321 096,40"], "Project_Title": ["Multivalent Molecular Systems for Innovative Applications"], "Total_Cost": ["EUR 2 321 096,40"], "Country": ["Italy", "Netherlands", "United Kingdom", "United Kingdom", "Netherlands", "Germany", "Germany"], "Project_ACR": ["MULTI-APP"], "Technology_Description": "This network brings together the major academic players active in Europe on the fundamentals and application of multivalency and cooperativity. The network is complemented by industrial partners ranging in scale from a small spin-off to a large multinational. The main objective of this consortium is to raise a new generation of researchers able to develop complex chemical systems that harness cooperativity for enhanced functional properties.", "To": ["2018-12-31, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-01-01"], "Project_ID": ["642793"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI CASSINO E DEL LAZIO MERIDIONALE", "STICHTING IHE DELFT", "TTY-SAATIO", "UNIVERSITE PARIS-EST"], "EU_Contribution": ["EUR 3 918 950,64"], "Project_Title": ["Advanced Biological Waste-to-Energy Technologies"], "Total_Cost": ["EUR 3 918 950,64"], "Country": ["Italy", "Netherlands", "Finland", "France"], "Project_ACR": ["ABWET"], "Technology_Description": "The Advanced Biological Waste-to-Energy Technologies (ABWET) EJD provides education and research at PhD level on environmental technologies that convert waste materials into bioenergy, training doctoral candidates to think globally and work in multidisciplinary research teams. This makes ABWET alumni attractive for European universities and industry, able to contribute to solving the global challenges of waste management, energy scarcity and sustainable development. ", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-EJD - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-EJD)"], "Funding_scheme": ["MSCA-ITN-EJD - European Joint Doctorates"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-01-01"], "Project_ID": ["643071"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["UNIVERSITY OF ESSEX"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["French-English bilinguals' processing of morphosyntactic structures: the case of cross-linguistic transfer"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["BilProcess"], "Technology_Description": "One question central to both bilingual first language acquisition (2L1) and second language development (L2) research is to understand the mechanisms that lead to systematic interaction between the languages, i.e. cross-linguistic influence (CLI). To-date, we know that bilinguals\u2019 two languages are continuously co-activated to some extent at the lexicon and sentence level. Bilinguals need to map different syntactic forms, i.e. one or more for each language, onto the same discourse function, which occasionally leads to the entrenchment of the non-targetlike form. Yet, little is known about how the age of acquisition (2L1 vs. L2) and language dominance (expressive abilities, language exposure) affect the processing mechanisms governing this phenomenon. ", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["752153"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF LEEDS"], "EU_Contribution": ["EUR 97 727,40"], "Project_Title": ["The effects of financial capital accumulation on employment and wealth distribution"], "Total_Cost": ["EUR 97 727,40"], "Country": ["United Kingdom"], "Project_ACR": ["FUSION"], "Technology_Description": "This project will analyse the relationship between the logic of financial accumulation and declining working conditions as well as the widening breach in social inequality affecting large segments of the European population. Studies carried out to date have failed to provide a systematic explanation for the relationship between financialisation, employment and wealth distribution. This project will contribute to filling this knowledge gap in the comparative cases of Spain and the UK, two different poles in terms of Eurozone economies.", "To": ["2018-07-02, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-03"], "Project_ID": ["746622"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CESSDA AS", "CHARLES BEAGRIE LIMITED", "ETHNIKO KENTRO KOINONIKON EREVNON", "TARKI ALAPITVANY", "TARTU ULIKOOL", "UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN", "INSTITUTO DE CIENCIAS SOCIAIS", "SVEUCILISTE U ZAGREBU FILOZOFSKI FAKULTET", "INSTITUT EKONOMSKIH NAUKA", "SOCIOLOGICKY USTAV SLOVENSKEJ AKADEMIE VIED", "UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA", "ASOCIATIA ARHIVA ROMANA DE DATE SOCIALE"], "EU_Contribution": ["EUR 2 498 187"], "Project_Title": ["Strengthening and widening the European infrastructure for social science data archives."], "Total_Cost": ["EUR 2 498 187"], "Country": ["Norway", "United Kingdom", "Greece", "Hungary", "Estonia", "Ireland", "Portugal", "Croatia", "Serbia", "Slovakia", "Italy", "Romania"], "Project_ACR": ["CESSDA-SaW"], "Technology_Description": "After CESSDA's successful launch we must now achieve full European coverage, and strength and sustainability for the widened network. ", "To": ["2017-10-31, closed project"], "Meta": [""], "Topic_s": ["INFRADEV-3-2015 - Individual implementation and operation of ESFRI projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Norway"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Other", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2015-08-01"], "Project_ID": ["674939"], "Call_for_Proposal": ["H2020-INFRADEV-1-2015-1"]}, -{"Partners": ["UNIVERSITAET BASEL"], "EU_Contribution": ["EUR 175 419,60"], "Project_Title": ["Emitter-mediated Photon-Phonon InteraCtion"], "Total_Cost": ["EUR 175 419,60"], "Country": ["Switzerland"], "Project_ACR": ["EPPIC"], "Technology_Description": "This action, \u201cEmitter-mediated Photon-Phonon InteraCtion\u201d (EPPIC), will contribute to the research areas of quantum computing and quantum sensors. These are key areas of the quantum technologies flagship initiative, which has the goal of establishing Europe as a leader in the second quantum revolution and its future industrial exploitation.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["747866"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF LIVERPOOL"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Iceland: Physical Anthropology of Colonization and Evolution"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["IPACE"], "Technology_Description": "Iceland was one of the last European countries to be settled, with the main period of migration taking place from the 9th to 10th centuries. After these initial migrations, the population of Iceland is thought to have been largely genetically isolated until the 20th century. It has been suggested that the initial populations were of Scandinavian and Irish descent, with some scholars suggesting that individuals of Irish decent accompanied the Scandinavian Vikings to Iceland as slaves. However, the accuracy of these suggestions is debated, making the genetic and cultural composition of the initial Icelandic population unclear. Therefore, there are a number of important questions regarding the settlement of Iceland and the mobility of early Europeans that remain unanswered. Three of these questions will be the focus of this study: Who were the initial settlers of Iceland? Did the colonisation of Iceland involve elements of the Viking slave trade? How did migration and subsequent isolation impact the biocultural diversity of the Icelandic human population? The proposed project will address these questions by investigating cranial shape with cutting-edge three-dimensional (3D) shape analysis techniques. The project will include analyses of Icelandic archaeological populations and individuals deriving from the two proposed colonizing populations \u2013 i.e. early Scandinavian and Irish human remains. Cranial shape variation will be analysed to identify relationships between the different populations and how Icelandic variation changed after settlement of the island. The findings of this project will significantly add to our understanding of early European migrations, as well as provide new insight into how migration to a new environment, possible adoption of a new diet, and exposure to a new gene pool influenced modern Icelandic population diversity.", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["748200"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSIDAD COMPLUTENSE DE MADRID"], "EU_Contribution": ["EUR 239 191,20"], "Project_Title": ["A new generation of AptaSensors"], "Total_Cost": ["EUR 239 191,20"], "Country": ["Spain"], "Project_ACR": ["APTASENS"], "Technology_Description": "The aim of this project is to design different next generation libraries of biosensors that will yield ready-to-go analytical tools against any target in unprecedented speed and high affinity. The project intends to focus on aptamers, a new generation of recognition elements that will be integrated into bioelectronics devices. ", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["656687"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Pasteur's Empire - French Expertise, Colonialism, and Transnational Science"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["PE-FECATS"], "Technology_Description": "This project investigates how bacteriologists at the Pasteur Institute reimagined the French empire as a biotechnological space of experimentation in the early twentieth century, and conversely, how medical technologies developed in French colonies in Indochina, West Africa and Tunisia were enrolled to both shore up and challenge colonial power. ", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["747591"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAET BASEL"], "EU_Contribution": ["EUR 175 419,60"], "Project_Title": ["Development of an artificial alkane monooxygenase: A leap in bioinspired oxidation catalysis"], "Total_Cost": ["EUR 175 419,60"], "Country": ["Switzerland"], "Project_ACR": ["TAML-ArM"], "Technology_Description": "The oxygenation of inert C-H bonds is a highly challenging reaction that has an enormous untapped potential for the European chemical industry. Indeed, it offers attractive means to upgrade cheap hydrocarbons into high value-added products. Nature relies on iron-based enzymes and oxygen to perform such transformations. In a biomimetic spirit, catalytic alkane hydroxylation is best achieved using iron-based catalysts and H2O2 as oxidant. Compared to natural enzymes, however, such systems display modest performance. In the TAML-ArM project, we aim to the development of a novel approach that consists of creating an artificial alkane monooxygenase by introducing a highly active iron complex within a protein scaffold. This strategy, pioneered in the Ward group, has ample precedent for less challenging reactions, and it potentially represents a significant step forward in bioinspired hydroxylation chemistry. To achieve this goal artificial metalloenzymes merge homogeneous- and enzymatic catalysis, two traditionally complementary strategies. We envision that this approach will: i) improve the catalytic activity by protecting the highly reactive Fe=O-moiety by shielding it from undesirable side-reactions and ii) provide novel selectivities, owing to second coordination sphere interactions between the protein and the substrate. Thanks to this innovative catalytic approach, we will develop a paradigm shifting technology for the selective hydroxylation of hydrocarbons: the reactions will be performed in water at room temperature using benign H2O2 as oxidant.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["747125"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["HELSINGIN YLIOPISTO"], "EU_Contribution": ["EUR 191 325,60"], "Project_Title": ["Speciation in ants: Unraveling the genetic, epigenetic and molecular basis of speciation using wood ants"], "Total_Cost": ["EUR 191 325,60"], "Country": ["Finland"], "Project_ACR": ["SpecIAnt"], "Technology_Description": "The enormous amount of diversity that surrounds us raises one of the key questions in evolutionary biology: How do new species originate? Speciation depends on the evolution of reproductive isolation but, with few exceptions, the genes underlying reproductive isolation and their modes of action are unknown. The novelty of this project lies in testing if, in addition to mutations in genes, epigenetics and gene expression are mechanisms that contribute to the process of speciation. For these aims I will use wood ants and their hybrids combining large-scale data sets on genomes, gene expression and genome-wide methylation. These approaches will be complemented with protein modeling of candidate genes resulting in a multidisciplinary project. Further aims are to develop an outreach programme on evolution for high schools and in collaboration with the Finnish Environment Institute to investigate the role of hybrids in forest ecosystems. Together these objectives yield a project that has high scientific standing and societal importance.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["750015"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FUNDACIO INSTITUT DE CIENCIES FOTONIQUES", "FUNDACIO INSTITUT DE CIENCIES FOTONIQUES"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Platform for label-free quantitative detection of single proteins and extracellular vesicles"], "Total_Cost": ["EUR 150 000"], "Country": ["Spain", "Spain"], "Project_ACR": ["IBIS"], "Technology_Description": "The main objective of the IBIS project is to develop an ultrasensitive, compact and low cost platform for the label-free quantitative detection of single proteins, and specifically the characterisation of nanometric extracellular vesicles. We will develop a prototype to transfer our novel detection scheme from the laboratory to the clinical environment and, based on user-feedback, develop a commercialization plan. ", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["755196"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["UNIVERSITAET BASEL"], "EU_Contribution": ["EUR 175 419,60"], "Project_Title": ["Fate of mammary stem cells during tumorigenesis and clinical implications"], "Total_Cost": ["EUR 175 419,60"], "Country": ["Switzerland"], "Project_ACR": ["MSCFate"], "Technology_Description": "One of the most challenging questions in breast cancer biology is to elucidate the origin of tumor heterogeneity and its contribution to therapy failure. Accumulating evidence suggests that the cell-of-origin, the cell that acquires the first oncogenic event, may define the molecular portrait of the resulting tumor. The fate of mammary Stem Cells (MSC) upon oncogenic perturbation has been poorly explored. Moreover, the Phosphoinositide 3-kinase (PI3K) pathway regulates proliferation/differentiation of MSC and is found hyperactive in breast cancer cells, for example through mutations in PIK3CA, the gene coding for its catalytic subunit. I hypothesize that expression of PIK3CA mutations will perturb mammary tissue homeostasis, initiate mammary cancer and trigger formation of stem-like cancer cells. Using state-of-the-art in situ genetic lineage tracing, I will determine the fate of MSC (identified recently as Procr+ cells) after conditional expression of PIK3CA hotspot mutations (H1047R, E545K). I will also characterize early molecular events responsible for promotion of transformation (Aim 1). When tumors develop, I will determine tumor phenotype and eventual progression to metastasis (Aim 2). Consequently, this study will generate a new mouse model of breast cancer that will be useful for preclinical studies. A panel of PI3K inhibitors is currently under Clinical investigation and clinical reports have shown that the combination of standard chemotherapy with PI3K inhibitors reduces tumor growth but drug-resistance often occurs. To identify resistance mechanisms to PI3K inhibitors, I will generate in vivo models of drug-resistance (Aim 3). My studies will use both hypothesis driven and unbiased approaches, they should: 1. better elucidate transformation of MSC and the resulting tumor heterogeneity, 2. pinpoint novel targets/biomarkers. Ultimately this knew knowledge should result in better therapies for patients.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["750812"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["QUEEN MARY UNIVERSITY OF LONDON", "QUEEN MARY UNIVERSITY OF LONDON"], "EU_Contribution": ["EUR 149 728"], "Project_Title": ["Biomimetic mineralization for enamel regeneration"], "Total_Cost": ["EUR 149 728"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["ENAMULATE"], "Technology_Description": "Dental enamel has a unique chemical composition and a remarkable well-defined hierarchical structure, which together are responsible for its outstanding properties and critical functionality. Once lost, this tissue cannot be regenerated and is directly involved in a variety of dental problems that affect a large percentage of the world population. This ERC PoC project (ENAMULATE) aims to develop the world\u2019s first human dental enamel regeneration material capable of recreating natural enamel in structure and chemical composition; treating dental defects; and replacing restorative materials currently used in dental clinics. The project builds on findings from the ERC Starting Grant STROFUNSCAFF on the development of an elastin-like protein (ELP) self-assembling process capable of triggering and guiding the hierarchical growth of hydroxyapatite as biocompatible, flexible, and robust coatings in vitro over large uneven areas and directly on human enamel and exposed dentinal tubules. ENAMULATE will optimize the crosslinking mechanism to facilitate its clinical use in the operating room, confirm its efficiency in vitro, and validate its performance in an established animal model. The project will also focus on setting up and moving forward a path towards commercialization by consolidating the intellectual property, investigating the industrial viability, and identifying potential markets.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["755191"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["UNIVERSITE DU LUXEMBOURG", "UNIVERSITE DU LUXEMBOURG", "KUNGLIGA TEKNISKA HOEGSKOLAN"], "EU_Contribution": ["EUR 2 499 595"], "Project_Title": ["Actively Enhanced Cognition based Framework for Design of Complex Systems"], "Total_Cost": ["EUR 2 499 595"], "Country": ["Luxembourg", "Luxembourg", "Sweden"], "Project_ACR": ["AGNOSTIC"], "Technology_Description": "Parameterized mathematical models have been central to the understanding and design of communication, networking, and radar systems. However, they often lack the ability to model intricate interactions innate in complex systems. On the other hand, data-driven approaches do not need explicit mathematical models for data generation and have a wider applicability at the cost of flexibility. These approaches need labelled data, representing all the facets of the system interaction with the environment. With the aforementioned systems becoming increasingly complex with intricate interactions and operating in dynamic environments, the number of system configurations can be rather large leading to paucity of labelled data. Thus there are emerging networks of systems of critical importance whose cognition is not effectively covered by traditional approaches. AGNOSTIC uses the process of exploration through system probing and exploitation of observed data in an iterative manner drawing upon traditional model-based approaches and data-driven discriminative learning to enhance functionality, performance, and robustness through the notion of active cognition. AGNOSTIC clearly departs from a passive assimilation of data and aims to formalize the exploitation/exploration framework in dynamic environments. The development of this framework in three applications areas is central to AGNOSTIC. The project aims to provide active cognition in radar to learn the environment and other active systems to ensure situational awareness and coexistence; to apply active probing in radio access networks to infer network behaviour towards spectrum sharing and self-configuration; and to learn and adapt to user demand for content distribution in caching networks, drastically improving network efficiency. Although these cognitive systems interact with the environment in very different ways, sufficient abstraction allows cross-fertilization of insights and approaches motivating their joint treatment.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Luxembourg"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["742648"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["DANMARKS TEKNISKE UNIVERSITET", "DANMARKS TEKNISKE UNIVERSITET"], "EU_Contribution": ["EUR 149 951"], "Project_Title": ["CodeSphere - Discovering Therapeutic Nanoparticles by Molecular Encoding"], "Total_Cost": ["EUR 149 951"], "Country": ["Denmark", "Denmark"], "Project_ACR": ["CodeSphere"], "Technology_Description": "There is currently no high-throughput method to efficiently identify and optimize nanoparticle delivery of therapeutic relevant cargo such as drugs or mRNA before progression through costly clinical development. This is in stark contrast to the situation for small molecules and antibodies, where screening technologies such as high-throughput small molecule screening and phage display in the last decades have proven very successful to aid and drive drug discovery and development.", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["767882"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["HELSINGIN YLIOPISTO"], "EU_Contribution": ["EUR 191 325,60"], "Project_Title": ["What is comparative legal history? Legal historiography and the revolt against formalism, 1930-60"], "Total_Cost": ["EUR 191 325,60"], "Country": ["Finland"], "Project_ACR": ["CLH"], "Technology_Description": "What is comparative legal history? This research aims to show that to understand the rise of this field of inquiry we need first to clarify how historiography changes in time. To this purpose, the proposed research begins from two main ideas.", "To": ["2019-09-20, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-21"], "Project_ID": ["753427"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF EXETER"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Sperm telomere length as a mediator of paternal effects"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["TELOSPERM"], "Technology_Description": "Despite having long been overlooked, paternal effects (influence of fathers on offspring traits via mechanisms other than the transmission of alleles) are now recognized as affecting a broad range of phenotypic traits in the next generation. There is, for example, increasing evidence for transgenerational effects of paternal stress levels with consequences on offspring health. In most cases, the proximate mechanism mediating these paternal effects on offspring remains unknown. ", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["746669"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["STICHTING KATHOLIEKE UNIVERSITEIT BRABANT", "STICHTING KATHOLIEKE UNIVERSITEIT BRABANT"], "EU_Contribution": ["EUR 1 499 046"], "Project_Title": ["Discriminative preferences and fairness ideals in diverse societies: An \u2018experimental economics\u2019 approach"], "Total_Cost": ["EUR 1 499 046"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["DIVERSE-EXPECON"], "Technology_Description": "In economics, a distinction is made between statistical and taste-based discrimination (henceforth, TBD). Statistical discrimination refers to discrimination in a context with strategic uncertainty. Someone who is uncertain about the future behaviour of a person with a different ethnicity may rely on information about the different ethnic group to which this person belongs to form beliefs about the behaviour of that person. This may lead to discrimination. TBD refers to discrimination in a context without strategic uncertainty. It implies suffering a disutility when interacting with \u2018different\u2019 others. This project systematically studies TBD in ethnically diverse societies.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["724231"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITA CA' FOSCARI VENEZIA", "UNIVERSITA CA' FOSCARI VENEZIA"], "EU_Contribution": ["EUR 1 999 976"], "Project_Title": ["Institutions and Metaphysics of Cosmology in the Epistemic Networks of Seventeenth-Century Europe"], "Total_Cost": ["EUR 1 999 976"], "Country": ["Italy", "Italy"], "Project_ACR": ["EarlyModernCosmology"], "Technology_Description": "The focus of this project is the competing confessional discourses on cosmology of the seventeenth century, an epoch in which religious conflicts originated opposing \u2018epistemic cultures\u2019, which were embodied in scholarly institutions and networks such as the Protestant web of northern European universities or the global web of Jesuit colleges.", "To": ["2022-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["725883"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE"], "EU_Contribution": ["EUR 2 500 000"], "Project_Title": ["Additive Micro-Manufacturing for Plastic Micro-flectro-Mechanical-Systems"], "Total_Cost": ["EUR 2 500 000"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["MEMS 4.0"], "Technology_Description": "The manufacturing of silicon-based MEMS today is well advanced because the micro-electro-mechanical devices for automotive, domestic, health-care and consumer electronics can be fabricated with methods from IC industry. Polymer-based MEMS have a great potential for flexible electronics and biomedical applications, but to date, the techniques to engineer functional polymers into 3D microsystems are still at their beginning because a coherent fabrication platform with the right tools and processes does not yet exist. The field could tremendously benefit from a coordinated effort in materials and manufacturing, in particular with a focus on biocompatible plastic materials for biomedical applications. Additive manufacturing such as 3D printing and associated processing such as sintering has already started to transform traditional industry, but is not scalable much below a micrometer because the thermal processing is done in bulk or by lasers on surfaces. MEMS 4.0, in analogy with the industry 4.0 concept, aims to perform concerted research in additive manufacturing at the micro/nanoscale and associated key techniques. Using my expertise in MEMS and Nanotechnology, MEMS 4.0 will push the frontiers in new materials and new processing for MEMS by setting a focus on stencilling, printing, self-assembly and local thermal processing. This coherent processing framework will permit the use of delicate, soft, polymer materials to engineer the next generations of plastic MEMS. We are primarily targeting biodegradable implantable MEMS and permanently implantable glassy carbon MEMS. They are the most challenging to fabricate, but if successful, they also have an enormous impact for future wearables and implantables.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["742685"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITEIT TWENTE", "UNIVERSITEIT TWENTE"], "EU_Contribution": ["EUR 2 500 000"], "Project_Title": ["Chemical Reaction Engineering by Additive Manufacturing of Mesoscale MetaMaterials"], "Total_Cost": ["EUR 2 500 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["CREAM4"], "Technology_Description": "\"The management of mesoscale dynamics is the missing link in gaining complete control over chemical processes like heterogeneous catalysis. The ability to accurately position nanoscale active elements in cellular mesoscale (nm to \u00b5m-range) structures with high symmetrical order is instrumental in streamlining vital molecular or energetic paths. 3D periodicity in the structure that supports active or adsorption sites minimizes spatial variations in mass transport, whereas mesoscale control of the location of these sites gives a route to tuning activity and functionality. The introduction of mesoscale metamaterials expands the on-going trend in chemistry, of more and more dimensionally refined structured elements, a so to speak \"\"Moore's law in Process Intensification\"\". The roadmap to higher process efficiency dictates a next, disruptive step in mastering manufacturing control at smaller dimensions. The proposed disruptive technology to realize the required mesoscale features is Additive Manufacturing, which is the only method offering the desired freedom in shape, symmetry and composition. More specifically, this project explores electrospinning methods with precise intra-wire control of the position of active sites and accurately tuneable 3D inter-wire distances. This is seen as the ideal technique to reach the mesoscale material target, as the method is scalable to practical device volumes. The main ingredients of the novel technology are microfluidic networks to line up nanoparticles, before electrospinning them with integrated micromachined nozzles, and depositing them accurately in the form of 3D nanowire networks, using integrated circuit collector electrodes. Flow-through, cellular materials which are highly homogeneous in size and composition, or with intentionally embedded gradients, having features designed at the mesoscale, will be investigated for applications in the fields of heterogeneous catalysis and solar energy capture and conversion.\"", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["742004"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITEIT TWENTE", "UNIVERSITEIT TWENTE"], "EU_Contribution": ["EUR 2 937 500"], "Project_Title": ["Diffusive Droplet Dynamics in multicomponent fluid systems"], "Total_Cost": ["EUR 2 937 500"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["DDD"], "Technology_Description": "Liquid-liquid extraction - the transfer of a solute from one solvent to another - is a core process in chemical technology and analysis. The current challenge is to miniaturise the analyte extraction process and to optimize the extraction recovery and preconcentration factor. Lacking a priori calculations, this is now often done by trial-and-error. However, to control and optimize the extraction processes, it is crucial to quantitatively understand the diffusive droplet dynamics in multicomponent fluid systems. This is essential and urgently needed not only for modern liquid-liquid extraction processes for diagnostics & microanalysis, for droplet microfluidics, or in the paint & coating industry, but on larger scales also in remediation industry, in chemical technology, or in food processing. These applications of droplets governed by diffusion include cases of immersed droplets in the bulk & on a surface, single & multicomponent droplets & solvents, and cases with high droplet number density. In spite of their relevance, multiphase & multicomponent fluid systems with relevant diffusive droplet dynamics are poorly understood.", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["740479"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITEIT TWENTE", "UNIVERSITEIT TWENTE"], "EU_Contribution": ["EUR 1 498 613,75"], "Project_Title": ["Processing Citizenship: Digital registration of migrants as co-production of citizens, territory and Europe"], "Total_Cost": ["EUR 1 498 613,75"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["ProcessCitizenship"], "Technology_Description": "Intensifying migration waves are changing EU policies\u2015with Hotspots being set up in frontline countries\u2015but also the way knowledge about migrants, institutions and territory is created. Information systems are key enablers of this knowledge. They materialize legislative, political, administrative dynamics in which citizenship, state and territory are co-produced.", "To": ["2022-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-03-01"], "Project_ID": ["714463"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["UNIVERSITEIT TWENTE", "UNIVERSITEIT TWENTE"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Explore the potentialities of living implants for medical devices"], "Total_Cost": ["EUR 150 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["IMPLANTaLive"], "Technology_Description": "IMPLANTaLive coating technology provides an exciting business opportunity. IMPLANTaLive offers unique advantages of societal and economic importance such as public health and sick leave. ", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["737637"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["UNIVERSITAET BASEL", "UNIVERSITAET BASEL"], "EU_Contribution": ["EUR 1 466 916"], "Project_Title": ["Molecular Mechanical Adhesives"], "Total_Cost": ["EUR 1 466 916"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["MMA"], "Technology_Description": "Protein-based hydrogels are commonly used as adhesives and sealants in surgical settings. Fibrin gels, for example, are biocompatible, however their use is hampered by poor mechanical properties. Previous attempts to improve fibrin gel mechanics relied on interpenetrating networks in combination with PEO, collagen and other polymers, however, only modest improvements were observed. The important challenge lies in understanding how molecular design principles can influence gel mechanics on the macroscale. ", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["715207"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["UNIVERSITEIT TWENTE", "UNIVERSITEIT TWENTE"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["BioREAD; a Continuous Barrier Quality Monitoring System for Organs-on-Chip"], "Total_Cost": ["EUR 150 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["BioREAD"], "Technology_Description": "Organs-on-chip are expected to play a crucial role in the pharmaceutical industry for drug development and study of organs and diseases. We propose the development of an electrical detector that enables simple, versatile and continuous quality monitoring of these devices and is essential for commercialization. Combined with recent advances in stem cell technology, Organ-on-Chips can be used to do drug screening on an individual level. Therefore it can serve as instrument for personalized medicine, by determining the effectiveness of selected compounds, as well as possible side-effects to determine safe drug doses on a person-specific level. Moreover, Organs-on-Chip will greatly contribute to a further reduction in the need for animal testing. Besides the pharmaceutical industry, Organs-on-Chip hold great promise for the food and cosmetics industry to test the safety of products.", "To": ["2018-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["727641"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["LIVERPOOL JOHN MOORES UNIVERSITY", "AALTO-KORKEAKOULUSAATIO", "INSTITUTO SUPERIOR TECNICO", "GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER", "UNIVERSITY OF PLYMOUTH", "MAHIDOL UNIVERSITY", "UNIVERSITI KEBANGSAAN MALAYSIA", "UNIVERSITI TEKNOLOGI MALAYSIA", "Wuhan University of Technology"], "EU_Contribution": ["EUR 1 282 500"], "Project_Title": ["REliability and Safety Engineering and Technology for large maritime engineering systems"], "Total_Cost": ["EUR 1 417 500"], "Country": ["United Kingdom", "Finland", "Portugal", "Germany", "United Kingdom", "Thailand", "Malaysia", "Malaysia", "China"], "Project_ACR": ["RESET"], "Technology_Description": "Failure of large complex engineering systems often leads to catastrophic consequences. Their efficient and safe design and operation will avoid or reduce malfunctions, failures and accidents, which would have a significant impact on the daily life of the public in terms of service and product delivery, business interruption, economic losses, human injuries/fatalities, and property and environmental damage. ", "To": ["2021-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["730888"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["UNIVERSITEIT TWENTE", "UNIVERSITEIT TWENTE"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Vascular Tree Formation in Multi-Structural Tissue Engineering"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["VascArbor"], "Technology_Description": "Engineered tissues offer a great promise to the field of medicine as an alternative for donor tissues, for which the supply is not meeting the demands. However, the clinical application of engineered tissues is hampered. The integration of engineered tissues after implantation is limited due to the lack of a vascular network. Currently, strategies to include vascular networks rely on the spontaneous organization of vascular cells, or on the patterning of these cells. However, this results in either vascular networks that are not organized, or networks that lose their initial organization fast. This project will use a unique and novel approach to control vascular development and will therefore result in a vascular network with a controllable long-term organization. By allowing for anastomosis, and increasing nutrient delivery, this project will tackle an essential problem and will greatly enhance the clinical applicability of engineered tissues.", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["724469"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITEIT TWENTE", "UNIVERSITEIT TWENTE"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Sustainable and Advanced Membranes By Aqueous Phase Separation"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["SAMBA"], "Technology_Description": "Membranes play a critical role in the production of safe drinking water and in the treatment of human waste streams. However, membranes themselves are nearly always produced using costly, harmful and environmentally unfriendly aprotic solvents such as N-methyl-pyrrolidone (NMP), dimethylformamide (DMF), or dimethylacetamide (DMAC). This proposal describes a highly novel approach allowing the production of the next generation of advanced membranes without the need to use any organic solvents. Here we make use of so-called responsive polymers that can switch under aqueous conditions from a hydrophilic to a hydrophobic state by a simple change of, for example, pH. In the hydrophilic state, water dissolves the polymers and the so obtained solution can be cast as a thin film. Sudden immersion in a bath at a pH where the polymer becomes hydrophobic, leads to very sudden phase separation whereby the polymer coagulates into a porous film, a membrane. Control over the kinetics of this aqueous phase separation process allows for the fabrication of a large variety of porous structures. Furthermore, this process also works for two oppositely charged polymers, where polyelectrolyte complexation is used to induce phase separation. Crosslinking will be a natural way to guarantee membrane stability but can also be used to further modify/improve membranes. The very nature of this aqueous phase separation process is such that membrane additives that are typically associated with advanced membranes (responsive polymers, enzymes, polyzwitterions, metallic nanoparticles) can readily be incorporated. As such, aqueous phase separation not only allows solvent free membrane production, it also provides a very simple and versatile route for the production of membranes with advanced properties. Finally, the porous structures and novel materials developed within this project could be directly useful for other applications, ranging from adsorption processes and coatings to biomedical materials.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["714744"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["UNIVERSITAET BASEL", "UNIVERSITAET BASEL"], "EU_Contribution": ["EUR 1 999 941"], "Project_Title": ["Hydrogen isotopes in plant-derived organic compounds as new tool to identify changes in the carbon metabolism of plants and ecosystems during the anthropocene"], "Total_Cost": ["EUR 1 999 941"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["HYDROCARB"], "Technology_Description": "HYDROCARB is motivated by the enormous potential that stable hydrogen isotope ratios (\u03b42H values) in plant compounds have as hydrological proxy, but in particular as new proxy for the carbon metabolism in plants. Current conceptual models suggest that \u03b42H values in plant organic compounds are composed of (i) hydrological and (ii) metabolic signals. The hydrological information that is contained in \u03b42H values of plant material is now well understood and is often applied in (paleo-) hydrological research. In contrast, the metabolic information that is contained in plant \u03b42H values is mostly unknown. Intriguing recent research suggests, however, that metabolic signals in the \u03b42H values of plant organic compounds reflect the balance of autotrophic and heterotrophic processes in plants. This suggests that exciting and previously unknown opportunities exist to exploit \u03b42H values in plant compounds for information on the carbohydrate metabolism of plants, which would be relevant for a broad range of biological and biogeochemical disciplines.", "To": ["2022-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["724750"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSITAET HAMBURG", "BAYERISCHE JULIUS-MAXIMILIANS UNIVERSITAT WURZBURG", "TECHNISCHE UNIVERSITEIT EINDHOVEN", "SINGLE QUANTUM BV", "UNIVERSITY COLLEGE LONDON", "THE UNIVERSITY OF SHEFFIELD", "TOSHIBA RESEARCH EUROPE LIMITED", "UNIVERSITAET BASEL", "ATTOCUBE SYSTEMS AG"], "EU_Contribution": ["EUR 3 900 365,28"], "Project_Title": ["Novel Quantum Emitters monolithically grown on Si, Ge and III-V substrates"], "Total_Cost": ["EUR 3 900 365,28"], "Country": ["Italy", "France", "Germany", "Germany", "Netherlands", "Netherlands", "United Kingdom", "United Kingdom", "United Kingdom", "Switzerland", "Germany"], "Project_ACR": ["4PHOTON"], "Technology_Description": "We propose to forge a partnership between the leading European groups working on the next generation of solid state quantum emitters based on novel growth methods such as Droplet Epitaxy. Future, practical Nano-photonics and Quantum Circuits applications demand semiconductor quantum dots that can be grown on substrates with different lattice parameters (Si, Ge, GaAs), different substrate orientations (such as (001) and (111)) and tuneable optical, electrical and spin properties. All these requirements are met by high quality quantum dots grown with Droplet based Epitaxy techniques, circumventing the limitations of currently available systems based on strain-driven dot self-assembly. This vast novel research area at the crossroads of photonics, material science, quantum physics and nano-scale device fabrication will allow delivering top level multidisciplinary training to 15 early stage researcher (ESRs). The successful training of the ESRs by leading academic and 3 full industrial partners will be crucial for achieving the headline goals of this first ever consortium on droplet dot devices: (1) Entangled light emitting diodes with droplet dots grown on (111) substrates (2) Electrically triggered, droplet dot based single photon sources on Si/Ge substrates (3) Strain tuning in droplet dots without wetting layer: photon polarization and single spin control (4) Droplet Dot based single photon sources for non- classical light storage devices based on hybrid quantum systems (dots & laser-cooled atoms). The training and research progress will be discussed and monitored during the 4 project meetings, 3 summer schools and the final international conference on Droplet Dot Devices, all of which are open to the whole scientific community. We expect this network, based on the solid collaboration between growth groups, microscopists, quantum optics experimentalists and theorists to explore the full potential of this emerging technology.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["721394"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["UNIVERSITY OF PLYMOUTH", "DANMARKS TEKNISKE UNIVERSITET", "NORDIC BIOSCIENCE COMPOUND DEVELOPMENT A/S", "ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI", "PROGNOMICS LTD", "SWANSEA UNIVERSITY", "UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA", "CENTRO DE INVESTIGACION BIOMEDICA EN RED ENFERMEDADES NEURODEGENERATIVAS", "UNIVERSITATSMEDIZIN ROSTOCK", "ADVANCED MEDICAL PROJECTS SOCIEDAD LIMITADA"], "EU_Contribution": ["EUR 3 465 749,52"], "Project_Title": ["Blood Biomarker-based Diagnostic Tools for Early Stage Alzheimer\u2019s Disease"], "Total_Cost": ["EUR 3 465 749,52"], "Country": ["United Kingdom", "Denmark", "Denmark", "Italy", "United Kingdom", "United Kingdom", "Italy", "Spain", "Germany", "Spain"], "Project_ACR": ["BBDiag"], "Technology_Description": "Alzheimer\u2019s disease (AD) affects more than 7 million people in Europe and this figure is expected to double every 20 years. Despite intensive efforts, no disease-modifying treatments or preventive strategies are available. The lack of specific, sensitive and minimally invasive diagnostics to identify people with early-stage AD to be included in clinical drug intervention trials is among the main reasons for many notable trial failures. The main challenges in developing the required diagnostics are identification of AD biomarkers and development of their detection techniques. The complex and interdisciplinary nature of the research underlines the need for innovative training of a new generation of researchers in the field. BBDiag responds to such a need and establishes a much-needed ETN for blood based early-AD diagnostics to address these challenges. It brings together leading academic and industrial experts from five major consortia in Europe and uses their synergies to build a triple-i research & training platform with the required multidisciplinary expertise and cutting-edge technologies. BBDiag Fellows will be trained under the Vitae Researcher Development Framework innovatively combined with the BBDiag platform for gaining interdisciplinary scientific and transferable skills as well as personal quality, creative thinking and business mind-set. The ETN has a highly innovative research programme for the discovery of AD biomarkers, development of novel biosensing techniques and point of care tools, and for technological exploitation of the diagnostics. These advances will strongly support improved care provision and development of disease-modifying treatments and preventive strategies for AD patients. More importantly, BBDiag will deliver its first generation of 13 highly-skilled, creative and entrepreneurial Fellows, setting them on a path to successful careers in academia or industry to ensure that the medical and societal challenges imposed by AD are met.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["721281"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN", "LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN"], "EU_Contribution": ["EUR 2 414 500"], "Project_Title": ["Clonal Deletion versus Clonal Diversion: Footprints of Self-Tolerance in the T CellRepertoire"], "Total_Cost": ["EUR 2 414 500"], "Country": ["Germany", "Germany"], "Project_ACR": ["TOLERANCE FOOTPRINT"], "Technology_Description": "Self-tolerance is a key feature of the immune system; its failure causes autoimmune diseases such as Multiple Sclerosis or Type-1-Diabetes. Remarkably, T cell tolerance operates via two fundamentally different mechanisms: potentially dangerous cells are either eliminated (clonal deletion) or re-programmed to differentiate into regulatory T (Treg) cells (clonal diversion). Paradoxically, both tolerance modes can ensue from self-antigen-encounter in the thymus, and the parameters specifying these opposing cell-fates remain poorly understood. Moreover, the relative contribution of clonal deletion versus clonal diversion to tolerance at the level of diverse immune cell repertoires has not been determined. In particular, the paucity of antigen-specific cells is a major experimental obstacle to unravelling to what extent cells with shared autoreactive specificity, yet different T cell receptors (TCRs), are subject to either mode of tolerance.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["742290"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "THE REGENTS OF THE UNIVERSITY OF CALIFORNIA"], "EU_Contribution": ["EUR 211 825,20"], "Project_Title": ["Advancing Rechargeable-Batteries Through In Situ Techniques"], "Total_Cost": ["EUR 211 825,20"], "Country": ["United Kingdom", "United States"], "Project_ACR": ["ARTIST"], "Technology_Description": "Li-ion batteries (LIBs) have enabled the portable device revolution of the last two decades, and have undoubtedly had a dramatic societal impact, with rechargeable electronic devices now ubiquitous. The light Li-containing electrodes, and high working cell voltages (typically >3.5 V) make LIBs the most practical solution for many portable applications. However, when significantly larger storage capacity is demanded, such as in transportation or grid-based energy storage, the limited availability, and consequently elevated cost, of Li becomes prohibitive. This research project will investigate alternative battery technologies that use more earth-abundant ions for charge transport, namely Mg, to enable the next generation of energy storage devices. The atomic-scale mechanisms of Mg-ion insertion/extraction at electrode-electrolyte interfaces and how these interfaces evolve during charging/discharging will be investigated. Complementary in situ techniques will be used to investigate the evolution of electrode structure and chemical state using carefully designed model electrodes. The study of scaled-up electrodes integrated into complete batteries will extend this understanding to more realistic battery cycling conditions. This will provide important insights to help overcome the limitations of the materials currently used in Mg-ion batteries (MIBs). The ground-breaking nature of this proposal lies in the level of fundamental understanding we aspire to achieve based on in situ metrology. We thereby envision the rational design and optimisation of the next generation of rechargeable batteries, guided by more than just the existing empirical approach.", "To": ["2017-12-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-07-01"], "Project_ID": ["656870"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITY OF STRATHCLYDE", "INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE", "CENTRO ITALIANO RICERCHE AEROSPAZIALI SCPA", "ESTECO SPA", "UNIVERSITY OF DURHAM", "INSTITUT JOZEF STEFAN", "POLITECNICO DI MILANO", "UNIVERSITEIT GENT", "DEUTSCHES ZENTRUM FUER LUFT - UND RAUMFAHRT EV", "TECHNISCHE HOCHSCHULE KOLN", "INSTITUT VON KARMAN DE DYNAMIQUE DES FLUIDES"], "EU_Contribution": ["EUR 3 876 853,68"], "Project_Title": ["Uncertainty Treatment and OPtimisation In Aerospace Engineering"], "Total_Cost": ["EUR 3 876 853,68"], "Country": ["United Kingdom", "France", "Italy", "Italy", "United Kingdom", "Slovenia", "Italy", "Belgium", "Germany", "Germany", "Belgium"], "Project_ACR": ["UTOPIAE"], "Technology_Description": "In an expanding world with limited resources and increasing uncertainty, optimisation and uncertainty quantification become a necessity. Optimisation can turn a problem into a solution, thus the main focus of this ETN is to explore and develop new approaches to treat uncertainty in complex engineering systems and use novel optimisation techniques to efficiently deal with large scale problems with many objectives and uncertain quantities. It is generally recognised, in fact, that neglecting the impact of uncertainty on the design of any system or process can lead to unreliable design solutions. Common approaches that make use of safety margins to account for uncertainty in design and manufacturing are not adequate to fully capture the growing complexity of engineering systems and provide reliable and optimal solutions. ", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2017-01-01"], "Project_ID": ["722734"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["WEIZMANN INSTITUTE OF SCIENCE", "WEIZMANN INSTITUTE OF SCIENCE", "INTELLISIV LTD"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Quantum-dot doped polymer fibers for cheap and bright light sources."], "Total_Cost": ["EUR 150 000"], "Country": ["Israel", "Israel", "Israel"], "Project_ACR": ["QDLight"], "Technology_Description": "In optical microscopy low-cost solid state LEDs and lasers have replaced traditional light sources. Major drawbacks of such, typically fiber-coupled light sources are poor flexibility, low modularity and high cost. Since a complete separate system is needed for every excitation color, the size of the economical investment is hindering the adoption of the technology directly contributing to improved research quality in multiple disciplines.", "To": ["2017-06-30, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2015 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-01-01"], "Project_ID": ["680132"], "Call_for_Proposal": ["ERC-2015-PoC"]}, -{"Partners": ["JIHOCESKA UNIVERZITA V CESKYCH BUDEJOVICICH"], "EU_Contribution": ["EUR 142 720,80"], "Project_Title": ["Socs3 gene in oocyte maturation and fertilisation - a novel link between inflammation and infertility"], "Total_Cost": ["EUR 142 720,80"], "Country": ["Czech Republic"], "Project_ACR": ["OOCSOCS"], "Technology_Description": "Increasing maternal age, a prevalent trend in developed countries, negatively influences oocyte quality and consequently female fertility \u2013 5% of all couples experience fertility problems arising from a physiological source in the women. To develop novel approaches to prevent or treat infertility, a more complete understanding of oogenesis is required. The host laboratory has recently identified the Socs3 gene, to date associated only with roles in the immune system, as a novel strong candidate regulating oogenesis. The project exploits a genetic approach to ablate the Socs3 gene from the female germ-line and addresses the role of Socs3 gene during mouse oocyte maturation and fertilisation, e.g. in correct chromosomal segregation, followed by further detailed and cutting-edge functional characterisation. The results could lead to the identification of novel therapeutic targets to treat female infertility. Dr. Veselovska, coming from a world-renown institute, is joining a well-established early mammalian development orientated host group, within the Department of Molecular Biology at the University of South Bohemia. Synergies arising from this multidisciplinary proposal will benefit both host and applicant. In particular, Dr. Veselovska is bringing a wealth of highly relevant mouse oocyte experience and bioinformatics skills for genome-scale analyses that are currently an underrepresented skills set in the host laboratory and host institution, as well as her network of UK based collaborators. She will receive training that is both complementary to her current knowledge and skills and novel and highly contemporary in relation to the experimental approaches used. Consequently, the fellowship award will substantially further the Dr. Veselovska\u2019s career ambitions to become an independent early mammalian developmental biologist within her native Central European region, and facilitate the under-represented exchange of ideas between Western and Eastern European countries.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Czech Republic"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["708255"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["KARLSRUHER INSTITUT FUER TECHNOLOGIE", "IBM RESEARCH GMBH"], "EU_Contribution": ["EUR 515 332,70"], "Project_Title": ["Capillary systems for advanced point-of-care diagnostics"], "Total_Cost": ["EUR 515 332,70"], "Country": ["Germany", "Switzerland"], "Project_ACR": ["CAPSYS"], "Technology_Description": "The worldwide in vitro diagnostic (IVD) is continually growing. At least 36% of the IVD market comprises point-of-care (POC) tests, which are performed by healthcare professional in various settings or by patients themselves. A large number of companies entered the POC testing market in the recent years while bringing significant technological improvements and novel concepts to this market. Yet, many important needs for immunodiagnostics are unmet: POC tests still require relatively large volumes of samples, cannot readily be multiplexed, are not always accurate, and often involve simple liquid displacement \"\"from point A to point B\"\" with minimal control over the distribution of reagents and kinetics of reactions.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-01-01"], "Project_ID": ["764476"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["SCUOLA NORMALE SUPERIORE", "SCUOLA NORMALE SUPERIORE"], "EU_Contribution": ["EUR 2 151 875"], "Project_Title": ["The Interstellar Medium of High Redshift Galaxies"], "Total_Cost": ["EUR 2 151 875"], "Country": ["Italy", "Italy"], "Project_ACR": ["INTERSTELLAR"], "Technology_Description": "When and how did the first galaxies form across Cosmic History? Were they different from present-day ones? This is only a small subset of key cosmological questions that the combination of deep galaxy observations, theoretical modeling, and powerful simulations envisaged here will allow us to answer for the first time. ", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["740120"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITY OF BATH"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Numbers in the brain: the impact of brain lateralization on numerical abilities"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["NUMELAT"], "Technology_Description": "Understanding the neural correlates of number cognition is of both intellectual and societal importance: number cognition gives fundamental insight into the evolution of cognitive processes and poor numeracy limits life chances and is a substantial cost to nations.", "To": ["2020-05-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-06-01"], "Project_ID": ["750200"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["BALTIJOS PAZANGIU TECHNOLOGIJU INSTITUTAS", "ALEKSANDRO STULGINSKIO UNIVERSITETAS", "VIESOJI ISTAIGA SOCIALINIU INOVACIJU INSTITUTAS", "KAUNO TECHNOLOGIJOS UNIVERSITETAS", "LIETUVOS ISTORIJOS INSTITUTAS", "VILNIAUS GEDIMINO TECHNIKOS UNIVERSITETAS VIESOJI ISTAIGA", "VILNIAUS UNIVERSITETAS", "VYTAUTO DIDZIOJO UNIVERSITETAS"], "EU_Contribution": ["EUR 140 405,75"], "Project_Title": ["Researchers' Night: It's Your Friday to Discover!"], "Total_Cost": ["EUR 140 405,75"], "Country": ["Lithuania", "Lithuania", "Lithuania", "Lithuania", "Lithuania", "Lithuania", "Lithuania", "Lithuania"], "Project_ACR": ["LT2016"], "Technology_Description": "\"The LT2016 Researchers\u2019 Night projects for 2016 and 2017 will take place in major Lithuanian cities, i.e. Vilnius, Kaunas, Klaipeda, Siauliai and Moletai, as well as in rural areas. The project aims to enhance public recognition of researchers and their work through bringing scientists and public closer to one another and thus increasing an understanding of the impact of researchers' work on citizen's daily life as well as encouraging young people to choose careers in science and research. Both events will offer a broad range of varied activities addressing all categories of the public at large, regardless of age and scientific background, i.e. notably: Meetings and activities together with researchers; Lectures, discussions; Visits to open laboratories; Real life observations and experiments; European corners; Various contests, games, exhibitions, movie and online broadcast watching. All the activities planned will actively involve researchers and will offer a balanced combination of \"\"serious\"\" activities and funny ones to be attractive for the general public. Activities will be hosted in labs, lecture halls, meeting places, cafes, while in the rural areas they will take place in schools or public spaces. Some activities conducted in the main sites will be broadcasted online. Common concept for the Night in 2016 and 2017 will be Learning about Technology Futures. Therefore activities of Researchers\u2019 Night projects in 2016 will be organised with focus on Virtual Reality thus building foundations for the Night in 2017 which will focus of \"\"science futurity\"\" or Futures of technologies. Both events will be finalised with the grand event unifying different fields - music, science and cinema. We expect at least 500.000 people made aware of the Researchers' Night and its objectives through the awareness campaign and 11.500 direct attendees to the various events planned in 2016 as well as in 2017.\"", "To": ["2017-11-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-NIGHT-2016 - European Researchers' Night"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Lithuania"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["722959"], "Call_for_Proposal": ["H2020-MSCA-NIGHT-2016"]}, -{"Partners": ["UNIVERSITAET BASEL", "UNIVERSITAET BASEL"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Bridging the gap between supramolecular chemistry and current synthetic challenges: Developing artificial catalysts for the tail-to-head terpene cyclization"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["TERPENECAT"], "Technology_Description": "Nature is a rich source of biologically active molecules, among which the largest and most diverse group of natural products are terpenes. Essential drugs like the cancer medication taxol/paclitaxel or the malaria drug artemisinin belong to the terpene family. They are efficiently formed in nature through a so-called tail-to-head terpene cyclization. Chemists are not able to mimic this process with man-made catalysts. This proposal aims at closing this significant research gap by utilizing supramolecular chemistry. Learning how to design such complex catalysts will not only enable us to mimic natural enzymes, but to enter uncharted territory of terpene chemistry.", "To": ["2021-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-11-01"], "Project_ID": ["714620"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["WEIZMANN INSTITUTE OF SCIENCE", "WEIZMANN INSTITUTE OF SCIENCE"], "EU_Contribution": ["EUR 2 437 500"], "Project_Title": ["Algorithms and experimental tools for integrating very large-scale single cell genomics data"], "Total_Cost": ["EUR 2 437 500"], "Country": ["Israel", "Israel"], "Project_ACR": ["scAssembly"], "Technology_Description": "Robust and flexible tissue -and cell-type specific gene regulation- is a definitive prerequisite for complex function in any multi-cellular organism. Modern genomics and epigenomics provide us with catalogues of gene regulatory elements and maps illustrating their activity in different tissues. Nevertheless, we are far from being able to explain emergence and maintenance of cellular states from such data, partly because we so far lacked characterization of individual molecular states and genome control mechanisms at their native resolution -the single cell-. Recently, new approaches developed by the single cell genomics community, with several contributions from our group, allow massive acquisition of data on the transcriptional, epigenomic and chromosomal conformation states in large cohorts of single cells. In this research program, we aim to move forward rapidly to bridge a major gap between these experimental breakthroughs and models of genome regulation in complex tissues. We will develop algorithms and models for representing data the transcriptional profiles, DNA methylation landscapes and Hi-C maps of literally millions of cells. Our tools will be designed specifically to leverage on new single cell RNA-seq, single cell Hi-C, single cell capture-pBat and higher order 4C-seq that we will continue to develop experimentally. Furthermore, we shall enhance and optimize our interdisciplinary framework hand in hand with a working model aiming at unprecedentedly comprehensive single cell analysis of E8-E10 mouse embryos. This will provide us with hundreds of worked-out cases of tissue specific gene regulation. The techniques and insights from these studies will then be used to characterize cell type aberrations and epigenetic reprogramming in tumors. The open algorithms, techniques and methodology we shall develop can accelerate research in multiple groups that will utilize single cell genomics to study numerous questions on gene regulation in the coming years.", "To": ["2022-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["724824"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Supracellular contractility dynamics and cell communication during collective chemotaxis."], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SUPRACELL_COMMUN_CCT"], "Technology_Description": "Collective chemotaxis (CCT) is a fundamental process for embryonic development and cancer metastasis, where groups of cells collectively migrate in response to a chemoattractive signal. While single cell migration depends on polarised actomyosin mechanotransduction and signalling cascades within the same cell, in CCT these functions are shared between different cells to achieve a coordinated, \u2018\u2018supracellular\u2019\u2019 translocation. The molecular mechanisms underlying coordination and cell-cell communication during CCT have been largely overlooked. I propose to address this issue using the neural crest (NC), a highly invasive mesenchymal cell population that migrates throughout the embryo via CCT. NC migration shows extensive similarities with cancer invasion, making it a useful model for studying metastatic migration. Preliminary experiments show that an actomyosin ring-shaped cable, which surrounds the NC cluster, contributes to maintain a supracellular organisation. Also, during CCT, gap junctions appear to regulate synchronous actomyosin contractions in cells located at the cluster\u2019s rear. Therefore, I will study this contractility dynamics in-vitro and in-vivo using Xenopus and zebrafish. I will manipulate the actomyosin cable to understand its contribution to efficient chemotaxis. Then, I will investigate how gap junctions enable synchronisation between neighbouring cells, by imaging the spread of calcium waves in NC clusters and manipulating other diffusible messengers. This study will give significant insights into the mechanisms regulating CCT, which is crucial for deepening our understanding of morphogenesis and cancer biology.", "To": ["2018-09-30, Grant Agreement terminated |"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["703100"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Mechanical regulation of tissue growth and signalling"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["MRTGS"], "Technology_Description": "The control of tissue size and morphology is a fundamental problem that is remarkably ill understood. Although extensive research has focussed on the genetic and biochemical control of tissue growth, significantly less attention has been paid to the mechanical aspect of growth regulation, even though ample evidence indicates that any deformation or shape change is, to some degree, a result of force acting on a mass. Unravelling the basis of the mechanical-biochemical co-regulation in tissue growth control will not only increase our understanding of organismal development but also potentially represent a novel therapeutic target in growth-related diseases such as cancer. With this in mind, I aim to address two central questions: ", "To": ["2017-12-31, Grant Agreement terminated |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["657088"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["RAREFUNCTIONS: The causes and consequences of spatial and temporal variation in rare traits."], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["RareFunctions"], "Technology_Description": "Rare species have long been the focus of conservation attention, but the commonness or rarity of particular characteristics or phenotypes is generally ignored. However, traits can also be rare, and evidence suggests that while rare traits tend to occur in rare species (and so are at greater risk of extinction), not all rare species have rare traits. Further, the diversity of traits present in a community (\u2018functional diversity\u2019) is closely tied to its function, and so rare traits may make essential contributions to ecosystem function and health. For example, predators may be rare in a system, but act as keystone species with effects across the food web. Given the possibility that rare traits make important contributions to ecosystem products and services and given their greater risk of extinction, it is imperative to explore this question of \u201cfunctional rarity\u201d. This project will help overcome the lack of a clear definition for functional rarity, the absence of geographical information on its distribution through space and time, and the need for experimental evidence tying the loss of rare traits to effects on ecosystems. This project aims to apply a system of classification to distinguish between different forms of functional rarity to a comprehensive database of plant diversity and trait values in French permanent grasslands. This will produce one of the most comprehensive inventories showing how functional rarity varies through space and time. In addition, RAREFUNCTIONS will use microbial microcosms to test how the loss of rare traits from a community alters ecosystem function. This proposal will establish baseline knowledge on the distribution of functional rarity in French permanent grasslands, a local hotspot of biodiversity and in decline, while also answering general questions about the causes and consequences of rare traits.", "To": ["2018-05-31, Grant Agreement terminated |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2016-06-01"], "Project_ID": ["657951"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["ISTITUTO NAZIONALE DI FISICA NUCLEARE", "JOHANNES GUTENBERG-UNIVERSITAT MAINZ", "UPPSALA UNIVERSITET", "INSTITUTE OF HIGH ENERGY PHYSICS CHINESE ACADEMY OF SCIENCES"], "EU_Contribution": ["EUR 1 498 500"], "Project_Title": ["An innovative Cylindrical Gas Electron Multiplier Inner Tracker for the BESIII Spectrometer"], "Total_Cost": ["EUR 1 498 500"], "Country": ["Italy", "Germany", "Sweden", "China"], "Project_ACR": ["BESIIICGEM"], "Technology_Description": "Inner Trackers (IT) are key detectors in Particle Physics experiments; excellent spatial resolution, radiation transparency and hardness, and operability under high occupancies are main requirements. While planar Gas Electron Multiplier (GEM) detectors are common in modern spectrometers, only one Cylindrical-GEMs (CGEM) detector has been produced up to now by the KLOE2 Collaboration and is being commissioned.", "To": ["2018-12-31, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2015-01-01"], "Project_ID": ["645664"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["THE HEBREW UNIVERSITY OF JERUSALEM"], "EU_Contribution": ["EUR 263 385"], "Project_Title": ["Motor simulation: Evaluating the role of mirror neurons in humans through ECOG and Lesion Studies"], "Total_Cost": ["EUR 263 385"], "Country": ["Israel"], "Project_ACR": ["MOTOR SIMULATION"], "Technology_Description": "One of the most intriguing, yet controversial findings in neuroscience in the past two decades is the discovery of the mirror neuron system (MNS). These visuo-motor neurons discharge both when a monkey does a particular goal-directed action and also when it observes another individual doing a similar action. The result of this mechanism is thought to be the capacity to recognize that an individual is performing an action, to differentiate this action from others analogous to it, and to use this information in order to act appropriately. This mechanism has been proposed as the basis for social cognition, and deficits in social understanding, such as those seen in autism spectrum disorder, have been linked to deficits in the MNS. Here I propose to use 2 novel approaches to address the neurobiological and behavioral significance of the human mirror neuron system (hMNS). (a) I will use Electrocorticography (ECoG) in neurosurgical patients to assess where, when, and how neurons in the prefrontal, parietal and sensorimotor regions are involved in action recognition. (b) I will employ scalp EEG and behavioral measures in a unique cohort of patients with damage centered in the Inferior Frontal Gyrus (IFG) or the Inferior Parietal Lobule (IPL). If the IFG and IPL are the core regions of the hMNS, patients with lesions to these regions should show deficits in understanding others\u2019 actions, intentions and emotions (when these are expressed by body motion). This research will further our knowledge on the neural underpinnings of social understanding, and on the consequences of deficits in these neural networks.", "To": ["2018-06-30, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-07-01"], "Project_ID": ["655292"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["ECOLE DES HAUTES ETUDES EN SCIENCES SOCIALES"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Humanitarian Passions. The Survival of Christian Iconography in Contemporary Representations of Pain: a Visual Studies Approach"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["HumanitarianPassions"], "Technology_Description": "My research project aims at contributing to understanding the role played by mass communications in contemporary humanitarian crises, through a comparative study of representations of pain in the history of Western iconography.", "To": ["2017-06-14, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-06-15"], "Project_ID": ["658512"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["PERCUROS BV", "ACADEMISCH ZIEKENHUIS LEIDEN", "PROGREDUM GMBH", "TECOBIOSCIENCES GMBH", "ANTONETTI NADIA", "UNIWERSYTET JAGIELLONSKI", "UNIVERSITAETSMEDIZIN GOETTINGEN - GEORG-AUGUST-UNIVERSITAET GOETTINGEN - STIFTUNG OEFFENTLICHEN RECHTS", "PREVENTIA SOCIETA' A RESPONSABILITA' LIMITATA SEMPLIFICATA", "UNIVERSITA DEGLI STUDI DI CAMERINO", "BOURNEMOUTH UNIVERSITY", "ATONOMICS AS", "TACIT BIO INNOVATION LIMITED", "DE MARCHIS VERONICA", "ASSOCIAZIONE CULTURALE CASTELLI ROMANI GREEN TOUR", "AUGEAS ASSOCIAZIONE DI SPORT PROMOZIONE E TURISMO", "SYDDANSK UNIVERSITET", "HELRIK AND LOUW COMPANY LTD", "TECHNICKA UNIVERZITA VO ZVOLENE"], "EU_Contribution": ["EUR 2 430 000"], "Project_Title": ["Characterisation Of A Green Microenvironment And To Study Its Impact Upon Health and Well-Being in The Elderly As A Way Forward For Health Tourism."], "Total_Cost": ["EUR 2 430 000"], "Country": ["Netherlands", "Netherlands", "Germany", "Germany", "Italy", "Poland", "Germany", "Italy", "Italy", "United Kingdom", "Denmark", "United Kingdom", "Italy", "Italy", "Italy", "Denmark", "United Kingdom", "Slovakia"], "Project_ACR": ["CHARMED"], "Technology_Description": "Our society in Europe is still under prepared for the demographic changing situation of an ageing population which began several decades ago. This is visible in the age structure of the population and is reflected by the fact that the population aged 65 years and over is increasing in every European country. The growth in the elderly population may be explained by increased longevity, but at the same time, we also see an increase in debilitating conditions. However, it is also clear that the elderly are afflicted by challenging health conditions as a direct consequence of being elderly which impact their quality of life (QOL), e.g. living alone, depression, recovery from illness, immobility. This is what we would like to address. Living longer should be a privilege but there has been a collective failure to address social implications and QOL issues, where social care and the way it is funded are already in crisis. Our aim in this project is to couple the need for new societal approaches in addressing this changing demographic with improving the economy of green microenvironment sites, where health tourism and creating new jobs in this sector would in turn fund and provide benefits with respect to the well-being of the elderly. The ultimate outcome, through this pan-European academic and industrial project, will be: a) to derive cross-disciplinary and inter-sectorial knowledge of how to improve physical and mental well-being in the elderly, b) to characterise the environmental geology of Nemi and to correlate the identified features with improvements in health, well-being and recovery, c) to train a new generation of specialists in the sector of recreation and health for the tourism industry, d) the training of specialists in social and therapeutic horticulture (STH) as a way to improve physical and mental health, e) to create a model for health tourism, and f) to produce a business plan with an economic impact analysis.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Netherlands"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Other", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["734684"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["LULEA TEKNISKA UNIVERSITET", "THE UNIVERSITY OF BIRMINGHAM", "UNIVERSIDADE DE COIMBRA", "UNIVERSITA DEGLI STUDI DI FIRENZE", "TECHNISCHE UNIVERSITEIT EINDHOVEN", "INSTITUT VON KARMAN DE DYNAMIQUE DES FLUIDES", "RUHR-UNIVERSITAET BOCHUM", "GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER", "SIEMENS INDUSTRY SOFTWARE NV", "SENVION GMBH"], "EU_Contribution": ["EUR 3 811 804,92"], "Project_Title": ["Efficient harvesting of the wind energy"], "Total_Cost": ["EUR 3 811 804,92"], "Country": ["Sweden", "United Kingdom", "Portugal", "Italy", "Netherlands", "Belgium", "Germany", "Germany", "Belgium", "Germany"], "Project_ACR": ["AEOLUS4FUTURE"], "Technology_Description": "As wind energy is considered one of the most promising renewable energy resources, energy production technologies relying on wind energy are currently flourishing under the EU ambitious plan for 2020. Market demands to prepare a generation of researchers within the EU that are able to face the challenge of fulfilling the EU ambitious plan, to sustain the production of wind energy and to innovate and promote wind energy systems (WES) for the future needs, are clearly met in AEOLUS4FUTURE. The primary research aim is to develop a sustainable WES for a variety of EU needs. There are a number of detailed scientific and technical issues that will be addressed by the project starting from identifying the wind energy potential (off-shore and on-shore, including the built environment) to the design of a sustainable and highly efficient WES. Also the new challenging load conditions imposed on wind farms located on places where existing type of wind turbine towers are not suitable require the development of new type of support structures for wind energy converters. This fosters new structural concepts taking advantage of high performance materials e.g. high strength steel and novel maintenance free fasteners. In addition, while most research efforts and practical applications of wind energy have focused on large-scale wind installations in remote offshore or onshore areas, much less attention has been given to wind energy installations near buildings. The project has a major training aim to create technical experts who will be able to lead the necessary industrial developments in the WES, and have a broad overview of a new and emerging multi-disciplinary field. The project will thus enable a number of young scientists and engineers to obtain high level training in various technical aspects of the problem, to gain an overall understanding of how this work fits into the wider EU Directives and plans for the future and in doing so to improve their career prospects.", "To": ["2018-12-31, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["643167"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["ECOLE DES HAUTES ETUDES EN SCIENCES SOCIALES"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Global Inheritances: Personal Identification and Inheritance Rights in the Early Modern Spanish Empire"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["GLOBAL INHERITANCES"], "Technology_Description": "The aim of the project is to study the ways in which the institutions of the early modern Spanish Empire identified the legitimate heirs of mobile individuals coming from the Iberian peninsula who died suddenly, often without making a will, while they were in the monarchy\u2019s extra-European territories, thousands of kilometres away from their home towns and the places where their heirs lived. In the context of a global scale empire, and in the absence of reliable official documentation such as civil and property registers, both the property and identity of these mobile individuals was extremely uncertain. Who were the deceased? What property did they own? Who and where were their heirs? When they died thousands of kilometres away from Europe, how did the institutions transmit the inheritance to their legitimate heirs? How could the courts be sure who they were? How could heirs demonstrate their identities in order to safeguard their rights to succession? For those hundreds of thousands of subjects of the Catholic Monarchy now on the move around four different continents \u2013 and for their families too \u2013 identifying themselves and demonstrating their identities was an urgent and growing need.", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["655316"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UPPSALA UNIVERSITET"], "EU_Contribution": ["EUR 185 857,20"], "Project_Title": ["The evolutionary and ecological implications of mito-nuclear epistasis"], "Total_Cost": ["EUR 185 857,20"], "Country": ["Sweden"], "Project_ACR": ["MITONUC"], "Technology_Description": "The main hypothesis of the proposed research is that, contrary to common and long-standing belief, mitochondrial genetic variation is functional and plays a key role in evolutionary adaptation. I suggest that a novel understanding of selection on mtDNA can derive from simultaneously considering sex-specific selection and genetic interactions between mtDNA and nDNA. Because males are a genetic \u201cdead-end\u201d for mtDNA, mtDNA mutations that are detrimental for males but beneficial for females will spread. This will generate a male-specific genetic load (\u201cthe mother\u2019s curse\u201d). Further, the main energy producing pathway in eukaryotes (the OXPHOS pathway) is built collectively by products of the mitochondrial and the nuclear genome. Thus, mtDNA and nDNA are potentially entangled in an intricate web of epistatic interactions that dictates organismal metabolism. The proposed research is built upon a series of interrelated parts, and will use a very amenable insect model organism and employ a range of different research methodologies. Specific aims of the proposed research is (1) to assess the effects of mito-nuclear genotype on key life history traits such as metabolic rate and test whether these effects are sex-specific in line with the \u201cmother\u2019s curse\u201d and (2) to test the hypothesis that mito-nuclear interactions promotes the maintenance of polymorphism in mitochondrial genome through negative frequency dependent selection. This research will have a range of biological implications, ranging from applied medical genetics over our use of mitochondrial genetic markers in population genetics/biology to speciation and our understanding of thermal adaptation to climate change.", "To": ["2017-09-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["656338"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS", "LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN", "BIOMEDICAL SCIENCES RESEARCH CENTER ALEXANDER FLEMING", "FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA", "THE UNIVERSITY OF EDINBURGH", "Fundaci\u00f3 Institut d'Investigaci\u00f3 Biom\u00e8dica de Bellvitge", "KAROLINSKA INSTITUTET", "WEIZMANN INSTITUTE OF SCIENCE", "DIAGENODE", "UD-GENOMED MEDICAL GENOMIC TECHNOLOGIES KUTATAS-FEJLESZTESI ES SZOLGALTATO KFT", "MOSAIQUES DIAGNOSTICS GMBH", "AvantiCell Science Ltd"], "EU_Contribution": ["EUR 3 782 583,36"], "Project_Title": ["Chromatin Dynamics in Development and Disease"], "Total_Cost": ["EUR 3 782 583,36"], "Country": ["Greece", "Germany", "Greece", "Italy", "United Kingdom", "Spain", "Sweden", "Israel", "Belgium", "Hungary", "Germany", "United Kingdom"], "Project_ACR": ["Chromatin3D"], "Technology_Description": "The cell nucleus is organized and compartmentalized into a highly ordered structure that contains DNA, RNA, chromosomal and histone proteins which make up a structure called chromatin. The dynamics associated with these various components are responsible for regulating physiological processes and the overall stability of the genome. The destabilization of such regulatory mechanisms that act on the chromatin structure are implicated in pathologies such as cancer. Higher order organization of chromatin results in chromosomes which occupy discrete territories within the cell nucleus. Most nuclear processes occur or at least being initiated onto the chromosomes which makes them the main organizing factors in the nucleus. Several proteins that are involved in the replication of DNA, gene transcription and the processing of RNA are found enriched in discrete focal structures. An emerging question is how these structures assemble and are maintained in the absence of membranes and moreover what are the kinetics of stable binding and/or rapid exchange of their components. The dynamic assembly and modification of chromatin during developmental processes as well as the deregulation of such chromatin dynamics during the onset of disease lacks mechanistic insights at present. To address these questions we have put forward a multidisciplinary approach which involves molecular, cellular and systems level approaches by assembling a group of scientists from academia and industry with cross disciplinary expertise and capabilities.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Greece"], "Activity": ["Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Chiara Andreoli", "Tel.: +3901071781854", "Fax: +39 010 7170817", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["642934"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["UPPSALA UNIVERSITET"], "EU_Contribution": ["EUR 173 857,20"], "Project_Title": ["Combining Single Molecule and Ensemble approaches To Investigate Cas9 Target Search"], "Total_Cost": ["EUR 173 857,20"], "Country": ["Sweden"], "Project_ACR": ["CasMETICS"], "Technology_Description": "The CRISPR-Cas9 bacterial immune system has garnered intense interest both as a synthetic biology tool and as a biological system in its own right. Yet the ability of Cas9 to find its guide-RNA-directed binding site in a timely fashion remains mysterious. To find its binding site, the single-stranded guide RNA must recognize the appropriate homologous DNA target within double-stranded chromosomal DNA, without using ATP to melt dsDNA. Moreover, in vitro measurements of Cas9 target search seem to suggest that an individual Cas9 molecule should take on the order of months to discover its target site, far too long to defend against viral infections which can proceed to lysis in less than one hour. To begin to unravel these conundrums, I plan to measure Cas9 target search time in vivo, using both single molecule and bulk approaches. The single molecule assay will use fluorescently tagged dCas9 (a version of Cas9 non-functional for cleavage) targeted against the lac O1 binding site. At t=0 the synthetic inducer IPTG can be flowed in, dissociating LacI from the O1 binding site, and the amount of time needed for dCas9 to bind determined by time-lapse fluorescence microscopy. The bulk version of the assay will exploit the existence of a binding site for the restriction enzyme BsrBI in the lacO1 binding site. As in the single molecule assay, the clock is started by addition of IPTG to growing cells, and the time needed for dCas9 binding is quantified by observed how long is needed for dCas9 to confer protection against BsrBI cleavage of cross-linked and purified chromatin. Finally, I will perform high-speed tracking experiments on searching dCas9 molecules using electroporated fluorescent dye-labeled guide RNAs. These measurements should constrain mechanistic hypotheses about Cas9 target search, and may provide insight into other critical biological processes involving single stranded nucleic acids searching in double stranded nucleic acids, such as homologous recombination.", "To": ["2018-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-04-01"], "Project_ID": ["704206"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["ECOLE DES HAUTES ETUDES EN SCIENCES SOCIALES"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Enacting heritage: The aesthetic dynamics of cultural transmission"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["EnAct"], "Technology_Description": "Aesthetic behaviours and expressive activities carry out a crucial role in human cultural evolution. Aesthetic cognition is important for intersubjective attunement already in early childhood, and attends to cultural emergence and transmission of ideas, practices and norms. However, anthropological scholars haven't ever investigated the cognitive dynamics whereby aesthetic behaviours shape the symbolic processes of constitution and re-enactment of cultural heritage. The proposed research project seeks to address this lacuna by dealing with key issues relating to the role of aesthetic behaviours in cultural transmission. The study focuses on how aesthetic and expressive elements are mobilized in the course of social interaction creatively transforming and communicating knowledge.", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["655942"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["ECOLE DES HAUTES ETUDES EN SCIENCES SOCIALES"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Popular readers and clandestine literature: the case of an early modern translation of Petronius\u2019 Satyricon into Italian (17th C.)"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["PopClandSATYRICON"], "Technology_Description": "The project aims at an in-depth inquiry into a 17th-century unpublished manuscript bearing the translation of Petronius\u2019 Satyricon into Italian. The translation represents a unique document, not only because it is likely to be the first version of Petronius into a modern language, but also because it proves the diffusion of the Satyricon even within the public of popular readers.", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["707253"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITY OF SOUTHAMPTON", "INSTITUTO SUPERIOR DE ENGENHARIA DE LISBOA", "UPPSALA UNIVERSITET", "HELSINGIN YLIOPISTO", "UNIVERSITE PARIS-SUD", "CARLETON UNIVERSITY", "THE REGENTS OF THE UNIVERSITY OF CALIFORNIA", "University of Toyama", "ZEWAIL CITY OF SCIENCE & TECHNOLOGY", "UNIVERSITE ABDELMALEK ESSAADI"], "EU_Contribution": ["EUR 301 500"], "Project_Title": ["Non Minimal Higgs"], "Total_Cost": ["EUR 328 500"], "Country": ["United Kingdom", "Portugal", "Sweden", "Finland", "France", "Canada", "United States", "Japan", "Egypt", "Morocco"], "Project_ACR": ["NonMinimalHiggs"], "Technology_Description": "On July 4th CERN has announced the discovery of a scalar particle at the Large Hadron Collider (LHC), later identified as the Higgs boson. This scientific breakthrough was accomplished due to the joint efforts of thousands of scientists from all around the globe. This long awaited discovery increased our understanding of the world, providing an explanation for the mechanism from which all elementary particles acquire mass. However, there are still fundamental questions awaiting a clear answer: which model better describes nature when all observed properties of this new particle are taken into consideration? Will these new models help to solve other outstanding problems in elementary particle physics? The goal of this project is to look for answers to these crucial questions regarding our understanding of nature.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2015-06-01"], "Project_ID": ["645722"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["THE MANCHESTER METROPOLITAN UNIVERSITY"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["House and home: physical and emotional comfort in the country house, England and Sweden c.1680-1820"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["HAHPEC"], "Technology_Description": "Physical comfort and emotional well-being are common expectations and aspirations across 21st-century Europe. This fellowship explores an important episode in the historical development of these cultural and social norms. The 18th century was a time when the wealthy, at least, had access to a growing range of goods, commodities and technologies, and were becoming increasingly aware of their individual identity. The research focuses on the changing relationship between physical and emotional comfort in the context of the country house, and explores a number of key questions about how the desire for comfort related to gender and life course, and to material objects and the growing specialisation of domestic spaces; how it was perceived through different senses and how it was juxtaposed with feelings of discomfort; and how it was conceived and experienced in two contrasting countries within Europe \u2013 places with very different societies, economies and climates.", "To": ["2017-09-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["658812"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITAET BERN"], "EU_Contribution": ["EUR 187 419,60"], "Project_Title": ["Evidence Based Planning of Future Clinical Research"], "Total_Cost": ["EUR 187 419,60"], "Country": ["Switzerland"], "Project_ACR": ["EBAR"], "Technology_Description": "Clinical studies that are planned without prior consideration of existing evidence potentially experiment with an unnecessarily large number of patients or try to answer a question to which the answer is already available. This project aims to develop a framework of efficient and sustainable research planning that minimizes cost and has the potential to direct resource allocation by optimally planning future clinical studies based on existing evidence. A circular updating process is suggested; before a trial is planned the existing evidence (a network meta-analysis) about the effectiveness of all competing interventions is considered and its conclusiveness is statistically evaluated. If further experiments are needed these are designed considering patient\u2019s preferences and with an aim to render the existing evidence conclusive. The new data is then used to update the existing knowledge. This innovative approach to plan clinical studied requires methodological developments from various fields (biostatistics, operational research, epidemiology) and its feasibility will be evaluated in answering a real clinical question about the best intervention for a given condition and in designing a new trial. The circular updating process is of high interest to public research funding bodies, guideline developers and pharmaceutical companies. The project has a strong public engagement component as patients and major health care organizations are involved in many of the planned activities in the development of the circular updating process. The project will be carried out in a stimulating academic environment (University of Bern) with extensive experience in clinical trials and a secondment in Novartis is planned. I will acquire technical skills in clinical trials, will continue to produce high-impact publications and develop leadership skills. These additions to my curriculum will enable me to progress to an academic carrier in a high-profile European Institute.", "To": ["2018-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["703254"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UPPSALA UNIVERSITET"], "EU_Contribution": ["EUR 173 857,20"], "Project_Title": ["Bridging the gap: an evolutionary genomics approach to illuminate the prokaryote-to-eukaryote transition."], "Total_Cost": ["EUR 173 857,20"], "Country": ["Sweden"], "Project_ACR": ["Gap2bridge"], "Technology_Description": "Eukarya \u2013 one of the three Domains of Life along with Archaea and Bacteria (i.e. prokaryotes) \u2013 include all complex multicellular life forms, as well as a colossal diversity of unicellular microorganisms. At the cellular level, the gap between prokaryotes and eukaryotes is immense, with the latter cell types displaying a large number of complex subcellular organelles and molecular systems. The evolutionary origin of these unique features, and thus of the eukaryotic cell itself, remains one of the most fascinating enigmas in modern biology. Although many eukaryotic-signature proteins (ESPs) are known to trace back to the last eukaryotic common ancestor, their deeper evolutionary origins remain unclear. The major goal of the current proposal is to illuminate the prokaryote to eukaryote transition by elucidating the origin and subsequent evolution of ESPs, as well as their order of emergence. We will focus on the ESPs of archaeal origin with an emphasis on the specific contribution of the newly discovered Lokiarchaeota lineages to the origin of the eukaryotic cell. In addition, we will aim to determine the placement the eukaryote lineage within the tree of Life and infer the age of the \u201cfirst eukaryote\u201d. Finally, we will use a novel phylogenomic approach to infer the gene content of the archaeal ancestors of eukaryotes by mapping the evolution of ESPs along the tree of Life. For this purpose, we will analyse entirely novel genomic data from several uncultivated Lokiarchaeota lineages, as well as novel sequence data from deep-branching key eukaryotes. This project will integrate approaches from distinct disciplines within life sciences and computational sciences (including molecular evolution, genomics/metagenomics and cell biology), with a strong emphasis on phylogenomics. Altogether, the innovative nature of this work combined with state-of-the-art methods and novel key genome data will allow to gain unprecedented insights in the origin and early evolution of Eukarya.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["704263"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["FRIEDRICH-SCHILLER-UNIVERSITAT JENA", "FRIEDRICH-SCHILLER-UNIVERSITAT JENA"], "EU_Contribution": ["EUR 1 965 917"], "Project_Title": ["Unifying concepts in the topological design of non-crystalline materials"], "Total_Cost": ["EUR 1 965 917"], "Country": ["Germany", "Germany"], "Project_ACR": ["UTOPES"], "Technology_Description": "Glasses have traditionally been enabling materials to major societal challenges. Significant breakthroughs on many areas of technological progress have been very closely linked to the exploitation of glassy materials. It is strong consensus that this key role will persist in the emerging solutions to major global challenges in living, energy, health, transport and information processing, provided that the fundamental limitations of the presently available empirical or semi-empirical approaches to glass processing can be overcome.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["681652"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["UNIVERSITAET BERN", "UNIVERSITAET BERN"], "EU_Contribution": ["EUR 1 498 478"], "Project_Title": ["Characterizing Adaptation and Migration Events with Modern and Ancient Genomes"], "Total_Cost": ["EUR 1 498 478"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["CAMERA"], "Technology_Description": "BACKGROUND Ancient DNA research has recently entered the genomics era. Performing \u201cancient population genomics\u201d is now technically possible. Utilizing the temporal aspect of this new data, we can address fundamental evolutionary questions such as the amount of selection acting on the genome or the mode and tempo of the colonization of the world. AIMS The overall goal of the proposed research is to (i) generate and analyse data to answer two long standing questions in human evolution: understanding the molecular basis of human adaptation to high altitude and investigating the timing of the Polynesian-South American contact, (ii) develop statistical approaches that combine ancient and modern genetic data to estimate the timing and the intensity of a selective sweep and an admixture event. METHODOLOGY Application: We will collect, date and DNA sequence human remains. Combining the ancient genetic data, 14C dates with existing modern genomic data will allow us to increase the resolution as to the timing of the adaptive and the admixture event, respectively, while generating unique datasets. Theory: We will build on existing methods based on one-locus classical population genetic models to develop tools to analyse whole genome time serial data. RELEVANCE Ecological: The results will address the fundamental question of how much of the human genome is undergoing selection, better characterize one of the textbook examples of adaptation in humans and contribute to our understanding of the peopling of the Americas. Medical: We will gain insights into the fundamental stress physiology experienced at high altitude and therefore into altitude-related illnesses. Methodological: The methods developed in this project will not only benefit the growing field of ancient genomics but also other fields where data is collected in a temporal manner, such as experimental evolution and epidemiology", "To": ["2021-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-08-01"], "Project_ID": ["679330"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA"], "EU_Contribution": ["EUR 168 277,20"], "Project_Title": ["Stochastic Multi-Scale Modelling for the Analysis of Closed-Loop Interactions among Brain Networks"], "Total_Cost": ["EUR 168 277,20"], "Country": ["Italy"], "Project_ACR": ["STOMMAC"], "Technology_Description": "Brain functions likely emerge from the concerted, context-dependent operations of its microscopic and macroscopic networks. Therefore, the organization and operational principles of such complex systems may be best investigated by using multi-modal approaches, including concurrent measurements of neural activity on multiple spatiotemporal scales. Performing and interpreting such multi-scale measures, though, presents enormous challenges for both experimental and mathematical neuroscientists. Existing analysis methods, however, make limited use of newly acquired concurrent multi-scale information. To dramatically advance analysis methods for these data, I propose a novel multi-scale model that bridges the gap between single cell statistics and neural mass signals. The model describes mixed discrete statistics, covering single cell and small population spike trains, as well as continuous statistics, such as those describing mesoscopic and macroscopic measures of mass neural activity in neuroimaging experiments. These elements are combined by means of copulas, describing multivariate interactions within and between scales of activity. I will extend this method to the level of efficient applicability and, in the course of a secondment with Prof. Logothetis at the Max Planck Institute in T\u00fcbingen, exploit the technique to solve current problems of multi-scale analysis of interactions between cortical and subcortical brain areas. The new mathematical approach will lead to a set of new tools that I will disseminate in an Open Source format for maximal impact, and will be widely applicable to multi-modal recordings in animals and humans, in both research and clinical settings. My own application of this method to multi-modal datasets will establish a deeper general understanding of the mechanisms of large-scale communication among brain areas, with particular emphasis on the principles of communication among networks involved in the formation of declarative memory.", "To": ["2017-06-30, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Chiara Andreoli", "Tel.: +3901071781854", "Fax: +39 010 7170817"], "From": ["2015-07-01"], "Project_ID": ["659227"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UPPSALA UNIVERSITET", "UPPSALA UNIVERSITET"], "EU_Contribution": ["EUR 1 621 940"], "Project_Title": ["Contexts, networks and participation: The social logic of political engagement"], "Total_Cost": ["EUR 1 621 940"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["CONPOL"], "Technology_Description": "The statement that individuals\u2019 immediate social circumstances influence how they think and act in the political sphere is a truism. However, both theoretical and empirical considerations have often prevented political scientists from incorporating this logic into analyses of political behavior. In the CONPOL project we argue that it is necessary to return to the idea that politics follows a social logic in order to push the theoretical and empirical boundaries in explaining political behavior. That is, people do not act as isolated individuals when confronting complex political tasks such as deciding whether to vote and which party or candidate to vote for. Instead politics should be seen as a social experience in which individuals arrive at their decisions within particular social settings: the family, the peer group, the workplace, the neighborhood. In what way do parents and other family members influence an individual\u2019s political choices? What is the role of workmates and neighbors when individuals arrive at political decisions? Do friends and friends\u2019 friends affect how you think and act in the political sphere? To answer such questions the standard approach to gather empirical evidence on political behavior based on national sample surveys needs to be complemented by the use of population wide register data. The empirical core of the CONPOL project is unique Swedish register data. Via the population registers provided by Statistics Sweden it is possible to identify several relevant social settings such as parent-child relations and the location of individuals within workplaces and neighborhoods. The registers also allow us to identify certain network links between individuals. Furthermore, Statistics Sweden holds information on several variables measuring important political traits. A major aim for CONPOL is to complement this information by scanning in and digitalizing election rolls with individual-level information on turnout across several elections.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["683214"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["UNIVERSITAET BERN", "UNIVERSITAET BERN"], "EU_Contribution": ["EUR 1 999 437,50"], "Project_Title": ["Synthetic viability of homologous recombination-deficient cancers"], "Total_Cost": ["EUR 1 999 437,50"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["SYNVIA"], "Technology_Description": "Although various effective anti-cancer drug treatments have become available over the last decades, drug resistance remains the major cause of death of cancer patients. Striking examples are patients with tumors that are defective in DNA repair by homologous recombination (HR). Despite initial responses to cancer therapy, resistance of primary or disseminated tumors eventually emerges, which minimizes therapeutic options and greatly reduces survival. The molecular mechanisms underlying this therapy escape are often poorly understood.", "To": ["2021-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-07-01"], "Project_ID": ["681572"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["UPPSALA UNIVERSITET", "UPPSALA UNIVERSITET"], "EU_Contribution": ["EUR 1 968 750"], "Project_Title": ["Fundamental and Applied Science on Molecular Redox-Catalysts of Energy Relevance in Metal-Organic Frameworks"], "Total_Cost": ["EUR 1 968 750"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["MOFcat"], "Technology_Description": "Organometallic redox-catalysts of energy relevance, i.e. water and hydrogen oxidation, and proton and carbon dioxide reduction catalysts, will be incorporated into metal-organic frameworks (MOFs). Immobilization and spatial organization of the molecular catalysts will stabilize their molecular integrity and ensure longevity and recyclability of the resulting MOFcats. The organized environment provided by the MOF will enable the control of conformational flexibility, diffusion, charge transport, and higher coordination sphere effects that play crucial roles in enzymes, but cannot be addressed in homogenous solution and are thus largely unexplored. The effect that the MOF environment has on catalysis will be directly probed electrochemically in MOFcats that are immobilized or grown on electrode surfaces. In combination with spectroscopic techniques in spectroelectrochemical cells, intermediates in the catalytic cycles will be detected and characterized. Kinetic information of the individual steps in the catalytic cycles will be obtained in MOFs that contain both a molecular photosensitizer (PS) and a molecular catalyst (PS-MOFcats). The envisaged systems will allow light-induced electron transfer processes to generate reduced or oxidized catalyst states the reactivity of which will be studied with high time resolution by transient UV/Vis and IR spectroscopy. The acquired fundamental mechanistic knowledge is far beyond the current state-of-the-art in MOF chemistry and catalysis, and will be used to prepare MOFcat-based electrodes that function at highest possible rates and lowest overpotentials. PS-MOFcats will be grown on flat semiconductor surfaces, and explored as a novel concept to photoanode and -cathode designs for dye-sensitized solar fuel devices (DSSFDs). The design is particularly appealing as it accommodates high PS concentrations for efficient light-harvesting, while providing potent catalysts close to the solvent interface.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["681895"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["UNIVERSITA CA' FOSCARI VENEZIA", "UNIVERSITA CA' FOSCARI VENEZIA", "ECOLE DES HAUTES ETUDES EN SCIENCES SOCIALES"], "EU_Contribution": ["EUR 1 480 625"], "Project_Title": ["Bilingualism in Florentine and Tuscan Works (ca. 1260 - ca. 1416)"], "Total_Cost": ["EUR 1 480 625"], "Country": ["Italy", "Italy", "France"], "Project_ACR": ["BIFLOW"], "Technology_Description": "This project will undertake the first systematic investigation of the various literary documents that circulated simultaneously in more than one language in Tuscany, and especially Florence, between the mid-13th Century and the beginning of 15th Century. ", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["637533"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["UPPSALA UNIVERSITET", "UPPSALA UNIVERSITET"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Evolutionary Stability of Ubiquitous Root Symbiosis"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["HeteroDynamic"], "Technology_Description": "Virtually all terrestrial plants depend on symbiotic interactions with fungi. Arbuscular mycorrhizal (AM) fungi evolved over 450 million years ago, are obligate biotrophs and cannot complete their lifecycle without obtaining carbon from host roots. Mediating nutrient uptake and sequestering carbon in soil this symbiosis lie at the core of all terrestrial ecosystems. Plants on the other hand are facultative mycotrophs but under natural conditions all host roots are colonized as a result of multiple beneficial effects of AM fungi. In the symbiosis, both plants and fungi are promiscuous, forming interactions across individuals and species. In the absence of host-symbiont specificity and given their inability to discriminate among partners prior to interaction, evolutionary theory predicts that \u201cfree riders\u201d would evolve and spread. Yet AM fungi remain evolutionary and ecologically successful. I propose that this is thanks to their unique genomic organization, a temporally dynamic heterokaryosis.", "To": ["2021-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-04-01"], "Project_ID": ["678792"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["UNIVERSITY OF LEICESTER"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Urban Centres and Landscapes in Transition. The Mediterranean FarWest in Late Antiquity"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["MED-FARWEST"], "Technology_Description": "MED-FARWEST is a strongly innovative project that, focussing on the territory located in the far west of the Roman Empire, namely the Iberian Peninsula, will analyse two of the most interesting yet poorly understood phenomena of the crucial period of Late Antiquity (AD 300-700): 1. the complete abandonment of some cities and 2. the dismantling of the Roman rural world. Both phenomena have long seen consideration by a variety of independent researchers, but without satisfactory depth and explanation to the issue. This proposed project will be the first to apply a comprehensive multidisciplinary approach, exploiting techniques developed especially in the sub-discipline of Landscape Archaeology, in which the rural and urban worlds are analysed as a single unit, and thus as part of a single reality in transformation. Hispania provides an ideal \u2018test-bed\u2019 for the study given the results of new fieldwork, an availability of relevant sites (urban/rural), and recent published outputs. The applicant and the proposed Host (University of Leicester) and Partner Organizations (the CSIC-National Research Council of Spain and CINECA of Italy) can draw upon a rich vein of expertise, specialists, research, publications, equipment and infrastructure to generate data, models and results for this project. The approach to be developed will be of major value for addressing other aspects of Roman-late antique transformation in Hispania (urban, rural, social, demographic, economic), but, crucially, will also provide guidelines for analyses elsewhere in the Empire, thus enabling much closer dialogue in approaches and debates both for Late Antiquity and for other periods.", "To": ["2017-10-31, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-11-01"], "Project_ID": ["658045"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITAET BERN", "UNIVERSITAET BERN"], "EU_Contribution": ["EUR 1 953 000"], "Project_Title": ["Mechanisms of RNA-guided genome editing in eukaryotes"], "Total_Cost": ["EUR 1 953 000"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["G-EDIT"], "Technology_Description": "The goal of this project is to contribute to our understanding of RNA-mediated epigenetic mechanisms of genome regulation in eukaryotes. Ciliated protozoa offer a fantastic opportunity to investigate the complex process of trans-generational programming of chromosomal rearrangements, which is thought to serve as a form of immune defense against invasive DNA. Developmental processes in ciliates include extensive rearrangements of the germline DNA, including elimination of transposons and the precise excision of numerous single-copy elements derived from transposons. This process is considered to be maternally controlled because the maternal genome provides essential information in the form of RNA that determines the offspring's genome content and organization. This programmed DNA subtraction, the so-called \u2018RNA scanning\u2019 process, is mediated by trans-generational comparison between the germline and the maternal somatic genome. One of the most intriguing questions is how a complex population of small RNAs representing the entire germline genome can be compared to the entire rearranged maternal genome, resulting in the efficient selection of germline-specific RNAs, which are able to target DNA deletions in the developing genome. All this occurs in a very short time and involves a massively coordinated transport of all the components between three types of nuclei. This project focuses on characterizing the molecular machinery that can orchestrate the massive genome rearrangements in ciliates through nucleic acids and protein interactions. It also addresses the question how RNA targets DNA cleavage at the right place. In addition, this project aims to investigate the role of RNA in guiding chromosomal rearrangements in other eukaryotic systems, particularly in human cancer cells where genome editing often occurs on a large scale. This work may be the first step in providing novel insights into the process of programmed DNA rearrangements in higher eukaryotes.", "To": ["2021-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["681178"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["HEINRICH-HEINE-UNIVERSITAET DUESSELDORF", "HEINRICH-HEINE-UNIVERSITAET DUESSELDORF"], "EU_Contribution": ["EUR 2 499 457,50"], "Project_Title": ["hybridFRET - deciphering biomolecular structure and dynamics"], "Total_Cost": ["EUR 2 499 457,50"], "Country": ["Germany", "Germany"], "Project_ACR": ["hybridFRET"], "Technology_Description": "To understand and modulate biological processes, we need their spatiotemporal molecular models. In this project we propose to build these models by a holistic approach. The recent methodological and technical advances in fluorescence spectroscopy and microscopy as well as in multi-scale modelling of complex biochemical systems set the stage to tackle cross-fertilizing challenges in biophysics, biochemistry and cell biology. The applicant proposes to develop a novel integrative platform for a Molecular Fluorescence Microscope (MFM) to achieve ultimate resolution in space (sub-nanometer) and time (picoseconds) for characterizing structure and dynamics of proteins. MFM will combine Multi-parameter Fluorescence Detection with Computational Microscopy (molecular dynamics and coarse grained simulations) in a hybrid approach, first, to derive a complete molecular description of all fluorescence properties of the tailored dyes in proteins (objectives 1 and 2) and, second, to utilize this information in simulations to report on the protein properties (objective 3). In this hybrid approach high precision FRET measurements are the core experimental technique (hybridFRET). The MFM will allow us to tackle the central biophysical question of how intra- and intermolecular domain interactions modulate proteins' overall structure, dynamics, and thus ultimately function (objective 4). In this proposal we will apply MFM to two prototypic proteins of significant medical relevance. The combination with Multi-parameter Fluorescence Image Spectroscopy will exploit the ultimate resolution of the MFM for molecular protein imaging in live cells. To follow and ultimately understand biological processes, we need their spatiotemporal models of the integrative fluorescence spectroscopy platform. Until now, no holistic use of fluorescence spectroscopy for structural modelling of proteins has been reported.", "To": ["2020-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-12-01"], "Project_ID": ["671208"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["UPPSALA UNIVERSITET", "UPPSALA UNIVERSITET"], "EU_Contribution": ["EUR 1 525 000"], "Project_Title": ["Mosaic loss of chromosome Y (LOY) in blood cells - a new biomarker for risk of cancer and Alzheimer\u2019s disease in men"], "Total_Cost": ["EUR 1 525 000"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["DIALOY"], "Technology_Description": "My recent discoveries show that mosaic loss of chromosome Y (LOY) in peripheral blood is associated with increased risks of cancer and Alzheimer\u2019s disease (AD). These conditions are responsible for >50% of morbidity/mortality in aging men. More than 15% of men older than 70 show some degree of LOY and these men survive on average only half as long as men without LOY. Smoking is strongly associated with LOY and remarkably, the fraction of cells with LOY decreases after cessation of smoking. Cells with LOY can be detected, and disease risks predicted, many years before clinical manifestation of disease. These results of associations between LOY, cancer and smoking have been published in Nature Genetics and Science during 2014.", "To": ["2021-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["679744"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["UNIVERSITAET LEIPZIG", "UNIVERSITAET LEIPZIG"], "EU_Contribution": ["EUR 1 772 625"], "Project_Title": ["Form-frequency correspondences in grammar"], "Total_Cost": ["EUR 1 772 625"], "Country": ["Germany", "Germany"], "Project_ACR": ["FormGram"], "Technology_Description": "This project will document and explain a substantial number of grammatical universals by demonstrating a link between cross-linguistic patterns of language form and general trends of language use. The claim is that frequently expressed meanings tend to be expressed by short forms, not only at the level of words, but also throughout the grammars of languages around the world (form-frequency correspondences). A simple example is the asymmetry in the coding of present-tense forms and future-tense forms in the world\u2019s languages, as one out of a multitude of analogous cases: Present-tense forms tend to be short or zero-coded, while future-tense forms tend to be longer or to have an overt marker. This corresponds to a usage asymmetry: Present-tense forms are generally more frequent than future-tense forms, in all languages. The proposed explanation is that higher-frequency items are more predictable than lower-frequency items, and predictable content need not be expressed overtly or can be expressed by shorter forms. Form-frequency correspondences thus make language structure more efficient, but it still needs to be shown that there exists a mechanism that creates and maintains these efficient structures: recurrent instances of language change driven by the speakers\u2019 preference for user- friendly utterances. The project thus combines cross-linguistic research on grammar, cross-linguistic corpus research and historical linguistics in a ground- breaking way. For reasons that have to do with the history of the discipline, form-frequency correspondences are still largely overlooked and ignored by linguists, so the current project will have a significant impact on our general understanding of human language.", "To": ["2020-10-31, ongoing project |"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-11-01"], "Project_ID": ["670985"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["UNIVERSITAET BERN", "UNIVERSITAET BERN"], "EU_Contribution": ["EUR 1 928 125"], "Project_Title": ["Dissection of a cortical microcircuit for the processing of pain affect"], "Total_Cost": ["EUR 1 928 125"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["CorPain"], "Technology_Description": "It is a fundamental but still elusive question how nociceptive processing is performed in neuronal networks in the cortex for the conscious experience of pain.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["682905"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "UPPSALA UNIVERSITET", "FUNDACIO CENTRE DE REGULACIO GENOMICA", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "VIB", "THE UNIVERSITY OF EXETER", "LUNDS UNIVERSITET", "THE UNIVERSITY OF LIVERPOOL", "ASCIDEA COMPUTATIONAL BIOLOGY SOLUTIONS SL"], "EU_Contribution": ["EUR 3 889 393,20"], "Project_Title": ["Promoting SINgle cell GEnomics to explore the ecology and evolution of hidden microeuKaryotes"], "Total_Cost": ["EUR 3 889 393,20"], "Country": ["Spain", "Sweden", "Spain", "France", "Belgium", "United Kingdom", "Sweden", "United Kingdom", "Spain"], "Project_ACR": ["SINGEK"], "Technology_Description": "Environmental microbial surveys have revealed a remarkable diversity of microeukaryotic life in most ecosystems, the majority of which had previously escaped detection. From an ecological point of view this work highlighted our ignorance of critical microbial players in natural environmental processes, including primary production, biogeochemical cycling and trophic interactions such as parasitism and grazing. Consequently, our understanding of community function is partial, limiting our ability to study environmental change. While, from an evolutionary perspective, we are missing major components of the Tree of Life giving rise to a fragmented understanding of how major cellular functions have evolved. Single cell genomics (SCG), including single cell transcriptomics, is an emerging technology that has the potential to retrieve genomic information from individual uncultured microbes recovered directly from natural environments and promises to provide new tools to investigate microeukaryotes in unparalleled detail. The aim of this ITN is therefore to train a new generation of scientists with the highest expertise, in SCG, from the initial stages of cell sorting to genome sequencing and gene annotation, to the full exploitation of the data obtained. Such progress will allow the European research community for the first time to address critical ecological and evolutionary questions. SINGEK will drive training through research by both local and network-wide activities, secondments, and workshops, and by establishing an environment that extends far beyond each partner team. This training environment will also provide the transferable skills essential for successful career development. This network of well connected and highly qualified scientists with expertise in eukaryotic SCG will be ready to implement this technology beyond ecology and evolution to other fields such as biomedicine or biotechnology driving innovation across the EU.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-01-01"], "Project_ID": ["675752"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["KUNGLIGA TEKNISKA HOEGSKOLAN", "KUNGLIGA TEKNISKA HOEGSKOLAN"], "EU_Contribution": ["EUR 2 097 520"], "Project_Title": ["Flow physics and interaction of laminar-turbulent transition and flow separation studied by direct numerical simulations"], "Total_Cost": ["EUR 2 097 520"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["TRANSEP"], "Technology_Description": "The vision spelled out in this proposal is to overcome the failure of Computational Fluid Dynamics to tackle one of the central unsolved fluid physics problems, namely predicting the sensitive flow physics associated with laminar-turbulent transition and flow separation. A recent, highly influential report by NASA (Slotnick et al., 2014) clearly states that the major shortcoming of CFD is its \u201c\u2026 inability to accurately and reliably predict turbulent flows with significant regions of separation\u201d, most often associated with laminar-turbulent transition. ", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["694452"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["UPPSALA UNIVERSITET", "UPPSALA UNIVERSITET"], "EU_Contribution": ["EUR 1 738 690"], "Project_Title": ["Integrating spatial and genetic information via automated image analysis and interactive visualization of tissue data"], "Total_Cost": ["EUR 1 738 690"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["TissueMaps"], "Technology_Description": "Digital imaging of tissue samples and genetic analysis by next generation sequencing are two rapidly emerging fields in pathology. The exponential growth in digital imaging in pathology is catalyzed by more advanced imaging hardware, comparable to the complete shift from analog to digital images that took place in radiology a couple of decades ago: Entire glass slides can be digitized at near the optical resolution limits in only a few minutes\u2019 time, and fluorescence as well as bright field stains can be imaged in parallel. ", "To": ["2021-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-04-01"], "Project_ID": ["682810"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["FRIEDRICH-SCHILLER-UNIVERSITAT JENA", "FRIEDRICH-SCHILLER-UNIVERSITAT JENA"], "EU_Contribution": ["EUR 2 373 750"], "Project_Title": ["Multi-dimensional interferometric amplification of ultrashort laser pulses"], "Total_Cost": ["EUR 2 373 750"], "Country": ["Germany", "Germany"], "Project_ACR": ["MIMAS"], "Technology_Description": "Ultrafast lasers, which allow the concentration of light in space and time, have been instrumental in revolutionizing industrial production technologies, medical applications and cutting-edge fundamental research. A common demand for many applications is the combination of maximum pulse peak powers with maximum average powers, in extreme cases involving petawatt (PW) peak powers and megawatt (MW) average powers. Additionally, these parameters must be achieved together with an optimum beam quality and high efficiency. The MIMAS project aims to address these demands and enable new realms of performance for ultrafast lasers. ", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["670557"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 251 857,80"], "Project_Title": ["Higher-order interactions and Laplacian dynamics in complex networks: structure, dynamics and control"], "Total_Cost": ["EUR 251 857,80"], "Country": ["United Kingdom"], "Project_ACR": ["HIntNets"], "Technology_Description": "Complex networks are an essential ingredient of modern life, and underpin integral parts of our biological, physical, technological and socio-economic universe. Thus far, such networks have been mainly represented as graphs. However, while graphs can capture pairwise interactions between nodes, fundamental interactions in networks often take place between multiple nodes. For example, in socio-economic networks, the joint coordinated activity of several agents (e.g. buyer, seller, broker); the formation and interactions of coalitions; the emergence of peer pressure; and the existence of triadic closure are all prevalent.", "To": ["2020-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["702410"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["QUEEN MARY UNIVERSITY OF LONDON", "UNIVERSITEIT MAASTRICHT", "UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN", "LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN", "KAROLINSKA INSTITUTET", "LIFEARC"], "EU_Contribution": ["EUR 2 887 041,24"], "Project_Title": ["European Vascular Interventions and Therapeutic Innovation Network"], "Total_Cost": ["EUR 2 887 041,24"], "Country": ["United Kingdom", "Netherlands", "Ireland", "Germany", "Sweden", "United Kingdom"], "Project_ACR": ["EVOluTION"], "Technology_Description": "EVOluTION, a pioneering network within EU in view of its focus on endogenous protective mechanisms, is formed to provide training for 11 young researchers in innovative therapeutic strategies, integrating early detection and prevention, to yield novel approaches to the management of chronic vascular and metabolic diseases that affect the increasing ageing population of Western societies. Fully aligned with the knowledge triangle (business, research and higher education) platform being developed at the EU level, EVOluTION-trained young scientists will gain valuable knowledge and multidisciplinary skills: only interdisciplinary and cross-cutting research can lead to novel therapeutic tools and scientific angles to address these challenging medical, societal and industrial issues. ", "To": ["2020-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2016-04-01"], "Project_ID": ["675111"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH", "RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN", "UNIVERSITE DE STRASBOURG", "BOEHRINGER INGELHEIM PHARMA GMBH &CO KG", "UNIVERSITA DEGLI STUDI DI MODENA E REGGIO EMILIA", "ASTRAZENECA AB", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "UNIVERSITAET BERN", "LEAD DISCOVERY CENTER GMBH"], "EU_Contribution": ["EUR 2 555 534,16"], "Project_Title": ["Big Data in Chemistry"], "Total_Cost": ["EUR 2 555 534,16"], "Country": ["Germany", "Germany", "France", "Germany", "Italy", "Sweden", "Switzerland", "Switzerland", "Germany"], "Project_ACR": ["BIGCHEM"], "Technology_Description": "The advent of the big data era in chemistry and the life sciences requires the development of new computational analysis methods, which are not only of scientific, but also economic relevance. Currently, the international data market already grows six times faster than the entire IT sector, and growth rates further increase. Achieving and sustaining a leadership positions in the big data arena represent critically important challenges for the EU. The economic developments in the emerging big data field are science-driven. Due to complexity and heterogeneity of biochemical and biomedical data, large-scale data exploration and exploitation are intrinsically interdisciplinary tasks. BIGCHEM positions itself at interfaces between chemistry, computer science, and the life science to provide well-structured multidisciplinary training and educate high-in-demand computational specialists capable of operating in interdisciplinary and international research and business settings. Cornerstones of BIGCHEM\u2019s curriculum include on-line lectures and periodic schools taught by internationally leading experts in chemical and life science informatics, a balanced consortium of academia, SMEs, and large industry, and an unprecedented symbiosis of academic and industrial training and application components. Accordingly, BIGCHEM is well positioned to boost multilateral collaborations between academia and industry and train scientists who are highly competitive in the international big data market. In BIGCHEM\u2019s R&D and training activities, the development and evaluation of conceptually novel methods for large-scale data analysis, knowledge extraction, and information sharing with demonstrated practical application potential take center stage. The network has a clearly defined policy for exploitation of new IP through wide involvement of target users, SMEs, and large industry facilitated by the experienced technology transfer department of the coordinator's team.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-EID - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-EID)"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-01-01"], "Project_ID": ["676434"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["UNIVERSITAET BERN", "UNIVERSITAET BERN"], "EU_Contribution": ["EUR 2 255 788"], "Project_Title": ["Deciphering the greenhouse gas record in deepest ice using continuous sublimation extraction / laser spectrometry"], "Total_Cost": ["EUR 2 255 788"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["deepSLice"], "Technology_Description": "The recent anthropogenic global warming makes a detailed understanding of coupling processes between climate and biogeochemical cycles of pressing importance. The atmospheric archive of air bubbles enclosed in polar ice cores provides the only direct record of greenhouse gas changes in the past, and the key to understanding the related changes in biogeochemical cycles and climate/greenhouse gas feedbacks. ", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["667507"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["UPPSALA UNIVERSITET", "UPPSALA UNIVERSITET"], "EU_Contribution": ["EUR 2 496 972"], "Project_Title": ["The Violence Early-Warning System: Building a Scientific Foundation for Conflict Forecasting"], "Total_Cost": ["EUR 2 496 972"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["ViEWS"], "Technology_Description": "The challenges of preventing, mitigating, and adapting to large-scale political violence are daunting, particularly when violence escalates where it is not expected. Early-warning systems of sufficient quality and transparency do not exist, limiting the ability of the international community to effectively assist affected populations. We propose to develop, test, and iteratively improve a pilot Violence Early-Warning System (ViEWS) that is rigorous, data-based, and publicly available to researchers and the international community. This objective is challenging but feasible. The conflict research community has laid the ground for such a system through careful isolation of theoretically manageable sub-components of complex phenomena, and concomitant systematic, disaggregated data collection efforts. A major innovation in the project is to integrate these isolated research programs into a theoretically and methodologically consistent forecasting system, by means of dynamic simulation techniques in combination with Bayesian Model Averaging, and guided by continuous out-of-sample evaluation. This integration effort will not only allow an early-warning system of unprecedented scope and performance, but also build theoretically informative bridges between numerous compartmentalized conflict research programs. Concentrating on theoretical and methodological development, the pilot will be limited in scope to Africa but be scalable. ViEWS will provide early warnings for four forms of political violence: armed conflict involving states and rebel groups, armed conflict between non-state actors, violence against civilians, and forced population displacement, and apply these to specific actors, sub-national geographical units, and countries. Led by H\u00e5vard Hegre, the system will leverage the data resources within the Uppsala Conflict Data program, the world-leading provider of conflict data, in combination with a strong team of highly experienced conflict scholars.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["694640"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["FONDAZIONE BRUNO KESSLER", "A.P.E. RESEARCH SRL", "CSEM CENTRE SUISSE D'ELECTRONIQUE ET DE MICROTECHNIQUE SA - RECHERCHE ET DEVELOPPEMENT", "III-V LAB", "SINGLE QUANTUM BV", "UNIVERSITAET BERN", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "B.I. Stepanov Institute of Physics of the National Academy of Sciences of Belarus", "LFOUNDRY SRL"], "EU_Contribution": ["EUR 3 925 921,75"], "Project_Title": ["All Solid-State Super-Twinning Photon Microscope"], "Total_Cost": ["EUR 3 939 516,25"], "Country": ["Italy", "Italy", "Switzerland", "France", "Netherlands", "Switzerland", "Switzerland", "Belarus", "Italy"], "Project_ACR": ["SUPERTWIN"], "Technology_Description": "The goal of the project is to develop the technology foundation for an advanced optical microscope imaging at a resolution beyond the Rayleigh limit, which is set by the photon wavelength. The proposed microscope technique is based on super-twinning photon states (N-partite entangled states) with the de Broglie wavelength equal to a fraction of the photon wavelength. Such microscopy technique will comprise building blocks for object illumination, capturing of scattered twinning photons and data processing. Based on advanced group-III nitride and III-V alloy epitaxial growths and wafer processing techniques we will build the first solid-state emitter of highly entangled photon states, utilizing the cooperative effect of Dicke superradiance (super-fluorescence) emission. Single-photon avalanche detector arrays with data pre-processing capabilities sufficient for capturing high-order field correlation functions of scattered twinning photons will be developed. A dedicated data processing algorithm for extracting the image of an illuminated object from the statistics of scattered twinning photons will complement the hardware. The project goal is to demonstrate imaging at 42 nm spatial resolution using 5-partite entangled photons at 420 nm wavelength. This quantum imaging technology will open the way for compact, portable, super-resolution microscope techniques, with no moving parts and no requirements to the optical properties of the sample.", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-1-2014 - FET-Open research projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-03-01"], "Project_ID": ["686731"], "Call_for_Proposal": ["H2020-FETOPEN-2014-2015-RIA"]}, -{"Partners": ["ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "TECHNISCHE UNIVERSITEIT DELFT", "FRIEDRICH-SCHILLER-UNIVERSITAT JENA", "KARLSRUHER INSTITUT FUER TECHNOLOGIE", "HEPTAGON OY", "SUSS MICROOPTICS SA", "HOLOEYE PHOTONICS AG", "CARL ZEISS AG", "ASML NETHERLANDS B.V.", "NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO", "JCMWAVE GMBH", "DATALOGIC IP TECH SRL", "Meyer Burger Research AG"], "EU_Contribution": ["EUR 3 855 693,24"], "Project_Title": ["Lossless Photon management \u2013 Optical design for manufacture at different length scales"], "Total_Cost": ["EUR 3 855 693,24"], "Country": ["Switzerland", "Netherlands", "Germany", "Germany", "Finland", "Switzerland", "Germany", "Germany", "Netherlands", "Netherlands", "Germany", "Italy", "Switzerland"], "Project_ACR": ["NOLOSS"], "Technology_Description": "The target of this project is to prepare and train future engineers for the design challenges and opportunities provided by modern optics technology. Such challenges include lossless photon management, modelling at the system, components and feature level, and the link between design and technology. Today all optical designs are often perceived following different approaches, namely geometrical optics, physical optics and nano-photonics. Traditionally these approaches are linked to the different lengths-scale that are important to the system. Starting from the entire system that is macroscopic and uses geometrical optics, over the miniaturized unit that is based on micro-optics and needs physical optics design, down to the active nano-photonics entity that allows steering light truly at the nano-scale but which requires to be designed with rigorous methods that provide full wave solutions to the governing Maxwell\u2019s equations. A design for manufacture of next generation optical applications necessarily requires to bridge the gap between the different length scales and to consider the design at a holistic level. At the core are optical simulation models developed and used in the academic research and the one used for optical designs in industry. Up to now, only the academic partners apply an integral approach to include micro- and nano-photonics in their simulations. Together with the industrial partners projects will be launched to promote the academic developments in optical design and simulation over different length scales towards the industry. The industry will use the know-how to consolidate their expertise, expand their businesses, and occupy new fields of activities. For each research subject, may it be nano-photonics, micro-optics or system engineering, a channel can be provided to access particular knowledge and/or stimulate collaborations.", "To": ["2020-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-EID - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-EID)"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-04-01"], "Project_ID": ["675745"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["KARLSRUHER INSTITUT FUER TECHNOLOGIE", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "DANMARKS TEKNISKE UNIVERSITET", "KEMIJSKI INSTITUT", "UPPSALA UNIVERSITET"], "EU_Contribution": ["EUR 4 114 753,50"], "Project_Title": ["A new class of powerful materials for electrochemical energy storage: Lithium-rich oxyfluorides with cubic dense packing"], "Total_Cost": ["EUR 4 114 753,75"], "Country": ["Germany", "France", "Denmark", "Slovenia", "Sweden"], "Project_ACR": ["LiRichFCC"], "Technology_Description": "The LiRichFCC project will explore an entirely new class of materials for electrochemical energy storage termed \u201cLi-rich FCC\u201d comprising a very high concentration of lithium in a cubic dense packed structure (FCC). The process by which energy is stored in these materials constitutes a paradigm change in the design of battery materials and involves unexpected and surprisingly effective mechanisms: instead of storing lithium ions by intercalation into a stable host, lithium ions are populating and vacating lattice sites of the material itself. This new principle allows for unprecedented energy and power density compared to other battery materials and may revolutionize the use of batteries in applications involving a need for supplying large amounts of energy and power from small spaces.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-1-2014 - FET-Open research projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["711792"], "Call_for_Proposal": ["H2020-FETOPEN-2014-2015-RIA"]}, -{"Partners": ["UPPSALA UNIVERSITET"], "EU_Contribution": ["EUR 185 857,20"], "Project_Title": ["Alphaviral Immunotherapy against Glioblastoma"], "Total_Cost": ["EUR 185 857,20"], "Country": ["Sweden"], "Project_ACR": ["AVITAG"], "Technology_Description": "Alphaviral Immunotherapy against Glioblastoma", "To": ["2018-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["707093"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITAT POLITECNICA DE VALENCIA", "Centro Regionale Information Communication Technology scrl", "POLITECNICO DI MILANO", "SVEUCILISTE U ZAGREBU FAKULTET ELEKTROTEHNIKE I RACUNARSTVA", "PRO DESIGN Electronic GmbH", "THALES COMMUNICATIONS & SECURITY SAS", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "PHILIPS MEDICAL SYSTEMS NEDERLAND BV", "EATON INDUSTRIES (FRANCE) SAS"], "EU_Contribution": ["EUR 5 801 820"], "Project_Title": ["MANGO: exploring Manycore Architectures for Next-GeneratiOn HPC systems"], "Total_Cost": ["EUR 5 801 820"], "Country": ["Spain", "Italy", "Italy", "Croatia", "Germany", "France", "Switzerland", "Netherlands", "France"], "Project_ACR": ["MANGO"], "Technology_Description": "MANGO targets to achieve extreme resource efficiency in future QoS-sensitive HPC through ambitious cross-boundary architecture exploration for performance/power/predictability (PPP) based on the definition of new-generation high-performance, power-efficient, heterogeneous architectures with native mechanisms for isolation and quality-of-service, and an innovative two-phase passive cooling system. Its disruptive approach will involve many interrelated mechanisms at various architectural levels, including heterogeneous computing cores, memory architectures, interconnects, run-time resource management, power monitoring and cooling, to the programming models. The system architecture will be inherently heterogeneous as an enabler for efficiency and application-based customization, where general-purpose compute nodes (GN) are intertwined with heterogeneous acceleration nodes (HN), linked by an across-boundary homogeneous interconnect. It will provide guarantees for predictability, bandwidth and latency for the whole HN node infrastructure, allowing dynamic adaptation to applications. MANGO will develop a toolset for PPP and explore holistic pro-active thermal and power management for energy optimization including chip, board and rack cooling levels, creating a hitherto inexistent link between HW and SW effects at all layers. Project will build an effective large-scale emulation platform. The architecture will be validated through noticeable examples of application with QoS and high-performance requirements.", "To": ["2018-09-30, ongoing project |"], "Meta": [""], "Topic_s": ["FETHPC-1-2014 - HPC Core Technologies, Programming Environments and Algorithms for Extreme Parallelism and Extreme Data Applications"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-10-01"], "Project_ID": ["671668"], "Call_for_Proposal": ["H2020-FETHPC-2014"]}, -{"Partners": ["UNIVERSITAET BERN"], "EU_Contribution": ["EUR 187 419,60"], "Project_Title": ["Associational resistance and neighbor recognition of in common dandelion roots"], "Total_Cost": ["EUR 187 419,60"], "Country": ["Switzerland"], "Project_ACR": ["DARES"], "Technology_Description": "Plants are able to recognize the chemical cues from neighbors and modulate their investment into growth and defense accordingly. While the effects and mechanisms of neighbor recognition on above ground plant-herbivore interactions have been studied extensively, they have rarely been investigated below ground, despite the importance of root herbivores and root-root signaling. The key objectives of DARES are 1) to investigate how does the presence of conspecific and heterospecific neighbors affects the root metabolism and defenses of Taraxacum officinale and its resistance against its main natural enemy, the white grub Melolontha melolotha, 2) to identify the type of chemical information that T. officinale uses to recognize neighbors (above ground volatiles, below ground volatiles or root exudates), and 3) to identify the chemical compounds from neighboring plants that T. officinale responds to. The results of DARES will allow me to assess the importance of associational resistance for below ground interactions. Furthermore, the gained knowledge will help to employ plant-based control strategies of T. officinale as a weed and M. melolontha as a grassland pest.", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["704334"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["SVEUCILISTE U ZAGREBU, FAKULTET STROJARSTVA I BRODOGRADNJE"], "EU_Contribution": ["EUR 158 010"], "Project_Title": ["Structured Training and Advanced Research in Marine Active Structures"], "Total_Cost": ["EUR 158 010"], "Country": ["Croatia"], "Project_ACR": ["STARMAS"], "Technology_Description": "In the last 25 years the total amount of marine trade has nearly doubled. In the same period the container trade has undergone a tenfold increase, making the container fleet the fastest growing fleet at present. With 80% of total EU trade being transported by sea, the maritime transport is of the greatest importance to the EU. The increasing demand in container transportation is met by use of more containerships. Such ships with large bow and stern flares and fine underwater hull are severely hit by an effect known as parametric rolling. Accidents including container loss and vessel structural damage are reported from all around the world. Capsizing could be regarded as a rare event, but the consequences of such event are fatal (loss of the ship and the crew). Agencies, classification societies and the public are showing more and more interests in increasing the safety of large container ships. STARMAS is a highly interdisciplinary integrated research and training programme focused on the application of novel active control methods to increase safety, energy efficiency and quality of life at sea of the 21st century maritime transport. The problem of ship roll on rough seas will be tackled using novel active roll control methodologies. Bi-directional transfer of knowledge and cross-fertilisation between traditionally detached engineering disciplines will be unlocked, utilising a unique research approach to enduring engineering problems related to sea keeping, survival rate, and energy efficiency of marine vessels. The programme will boost the career prospects, increase employability and widen the set of skills of the experienced researcher. The training and research will predominately take place within the academic sector, at the Faculty of Mechanical Engineering and Naval Architecture (FAMENA). The researcher will also benefit from secondments to the non-academic partner Bureau Veritas, Paris, (BV) facilitating an inter-sectoral transfer of knowledge.", "To": ["2018-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Croatia"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["657539"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITAET BERN"], "EU_Contribution": ["EUR 187 419,60"], "Project_Title": ["The Effects of Media News about Immigrants on Majority\u2019s Attitudes and Behaviors towards Immigrants"], "Total_Cost": ["EUR 187 419,60"], "Country": ["Switzerland"], "Project_ACR": ["IMMIGRANTS"], "Technology_Description": "The interdisciplinary IMMIGRANTS project aims at a better understanding of how media influence majority\u2019s attitudes and behaviors towards immigrants \u2013 a socially pressing issue connected to rapid expansion of immigration in Europe. In the project, I will focus on different aspects of media news \u2013 their valence, labels used for immigrants\u2019 ethnicity and pictures of immigrants accompanying media articles about immigrants. The first goal of my research is to investigate how different labels used for immigrants\u2019 ethnicity (nouns vs. adjectives) combined with different valence of media articles about immigrants (positive vs. negative vs. ambivalent) influence participants\u2019 attitudes and behaviors towards immigrants. My second goal is to compare the effects of articles accompanied by different images of immigrants and articles without such images on participants\u2019 attitudes and behaviors towards immigrants. Both goals feature a number of tasks related to the effects of media articles on attitudes and behaviors towards immigrants: I will test underlying mechanisms (e.g., biometrically tracked positive and negative emotions) and boundary conditions (e.g., social status and category salience of an immigrant group, participants\u2019 intergroup contact with immigrants) of these effects. In three studies of the IMMIGRANTS project, I bring together different traditions on media and immigrant research and address several gaps in social scientific literature (e.g., too narrow focus on negative media news in political and media research, too narrow focus on positive intergroup contact and self-reported emotions in psychology). The outcome of IMMIGRANTS can be used to inform guidelines for professional training of journalists, policy makers, and social workers to become more sensitive to the impact of language describing immigrants.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["703495"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["ECOLE DES HAUTES ETUDES EN SCIENCES SOCIALES"], "EU_Contribution": ["EUR 201 024"], "Project_Title": ["Violent settlements: strategic villages and clandestine burial sites in Latin America"], "Total_Cost": ["EUR 201 024"], "Country": ["France"], "Project_ACR": ["StrategicVillages"], "Technology_Description": "In contemporary warfare the power to destroy cities exists alongside with the power to built urban places ex nihilo. In the 70s and 80s, various Latin American States forcedly displaced people to villages created as an instrument of counterinsurgency; at the same time massacres and forced disappearances occurred in these regions. How does the simultaneous creation of strategic villages and clandestine burial sites affect the ways of inhabiting and imagining space in the aftermath of political violence? My study aims at analysing for the first time the connexion between mass violence and the forced creation of built environment. Based on qualitative fieldwork undertaken in Tucum\u00e1n (Argentina) and Ayacucho (Peru) and framed within social anthropology, sociology and human geography, this research will produce a seminal in-depth study of the daily life among the strategic villages in Latin America, by analysing the experience of subjects that were forced to inhabit there.", "To": ["2019-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-02-01"], "Project_ID": ["654923"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["ECOLE DES HAUTES ETUDES EN SCIENCES SOCIALES", "FREIE UNIVERSITAET BERLIN", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 778 500"], "Project_Title": ["Understanding institutional change in Asia: a comparative perspective with Europe"], "Total_Cost": ["EUR 778 500"], "Country": ["France", "Germany", "United Kingdom"], "Project_ACR": ["INCAS"], "Technology_Description": "The project INCAS aims at creating a top-level research and advanced training network on institutional change in Asia, in comparative perspective with Europe. The coordinator, Ecole des Hautes Etudes en Sciences Sociales (France), promotes this network together with Oxford University, Freie Universit\u00e4t Berlin, in collaboration with Waseda University (Japan). The partners have chosen Japan as a reference point because of its comparability with Europe as shown by previous studies, its historical influence on development and further institutional changes in Asia, and the expertise accumulated within our research team.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-06-01"], "Project_ID": ["645763"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["CARDIFF UNIVERSITY"], "EU_Contribution": ["EUR 267 147"], "Project_Title": ["Southern Ocean and Antarctic Climatic Phasing:Tephrochronological Correlation of Southern Ocean Marine Records and Antarctic Ice-cores"], "Total_Cost": ["EUR 267 147"], "Country": ["United Kingdom"], "Project_ACR": ["SHARP"], "Technology_Description": "Determining the temporal relationships of large-scale atmospheric and oceanic fluctuations is crucial for advancing understanding of the mechanisms controlling heat transfer between the Northern and Southern Hemispheres. The thermal bipolar see-saw caused asynchronous interhemispheric climatic changes during the last glacial period and Southern Ocean marine records and the Antarctic ice-cores are valuable archives recording this past climatic variability. Ascertaining the precise phasing of the climatic variability between these records provides crucial boundary conditions for testing models simulating the future behaviour of the bipolar see-saw and assessing potential large-scale oceanic and atmospheric reorganisations under anthropogenic forcing. In addition, establishing tighter constraints on phase relationships between sedimentary evidence for deep-water ventilation of CO2, and ice-core evidence for past atmospheric CO2 variations is key to determining the future response of the Earth system to rising CO2 levels. This project will address this challenge by ascertaining the rate, timing and phasing of Southern Hemisphere climatic changes between 40-10 kyr BP using tephrochronology to independently synchronise the palaeoclimatic sequences using common horizons of volcanic ash as time-synchronous tie-lines. Recognition of ash horizons not visible upon core inspection (cryptotephras) within sequences increasingly distal from volcanic regions has increased the scope of this technique. Cryptotephra identification methods will be used to trace ash horizons visible in Antarctic ice-cores into a marine core network from the Southern Ocean Atlantic sector and to trace previously unknown horizons identified in the marine realm into the Antarctic Atlantic sector EPICA DML ice-core. This region has a high potential for synchronisation due to the number of upwind volcanic regions that have previously deposited volcanic ash over the ice-sheet and Southern Ocean.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["656381"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER", "UNIVERSITE DE REIMS CHAMPAGNE-ARDENNE", "UNIVERSITA DEGLI STUDI DELL'INSUBRIA", "PANEPISTIMIO PATRON", "UPPSALA UNIVERSITET", "\"NATIONAL CENTER FOR SCIENTIFIC RESEARCH \"\"DEMOKRITOS\"\"\"", "SEREND-IP GMBH", "FIDIA FARMACEUTICI SPA", "SEMMELWEIS EGYETEM"], "EU_Contribution": ["EUR 567 000"], "Project_Title": ["Matrix glycans as multifunctional pathogenesis factors and therapeutic targets in cancer"], "Total_Cost": ["EUR 567 000"], "Country": ["Germany", "France", "Italy", "Greece", "Sweden", "Greece", "Germany", "Italy", "Hungary"], "Project_ACR": ["GLYCANC"], "Technology_Description": "Cancer is a leading cause of mortality within the aging European population. Therapeutic targeting is hampered by the complexity of the disease, which includes not only molecular changes within the tumor cell itself, but also within its microenvironment. Tumor angiogenesis, tumor-stroma interactions, interactions with immune cells, with the extracellular matrix and cancer stem cell niches allow for malignant cell survival and promote metastasis, the leading cause for cancer-associated mortality. Proteoglycans (PGs) and glycosaminoglycans (GAGs) \u2013 structurally diverse carbohydrates of the extracellular matrix and cell surfaces - have emerged as novel biomarkers and molecular players both within tumor cells and their microenvironment, as they integrate signals from growth factors, chemokines and integrins, and cell-cell as well as matrix adhesion. Importantly, their expression is dysregulated in numerous tumor entities, and has been shown to modulate each of the hallmarks of cancer as defined by Hanahan and Weinberg (Cell 2011). We hypothesize that dysregulated function of PGs and GAGs simultaneously affects all molecular steps towards cancer metastasis as a general principle applicable to multiple tumor entities. Pharmacological modulation of their function thus emerges as an attractive multitargeted antitumoral approach which simultaneously acts at multiple levels of disease progression. Besides providing extensive knowledge transfer and training for researchers, the combined expertise of the GLYCANC consortium aims at performing a detailed structural analysis of PG and GAG glycans in disease using state-of-the art methodology, analysing their regulation via epigenetic mechanisms and microRNAs, and elucidating molecular mechanisms underlying aberrant PG and GAG function. GLYCANC will lead to a deeper understanding of glycan structures and glycan-dependent mechanisms promoting cancer progression, providing the basis for rational multitargeted anticancer approaches.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2015-07-01"], "Project_ID": ["645756"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["FRIEDRICH-SCHILLER-UNIVERSITAT JENA", "CCKF Ltd", "TECHNOLOGIKO PANEPISTIMIO KYPROU", "3S UNTERNEHMENSBERATUNG GMBH"], "EU_Contribution": ["EUR 679 500"], "Project_Title": ["Transforming European Women\u2019s Entrepreneurship: The Education and Training for Success Programme"], "Total_Cost": ["EUR 679 500"], "Country": ["Germany", "Ireland", "Cyprus", "Austria"], "Project_ACR": ["women entrepreneurs"], "Technology_Description": "The objective of the women entrepreneurs project is to set up and strengthen international and inter-sectoral collaboration in the research field of competence development in young women entrepreneurs and to promote women\u2019s entrepreneurial potential in Europe. ", "To": ["2019-02-28, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-03-01"], "Project_ID": ["645441"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["FREIE UNIVERSITAET BERLIN"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Certifying Large-scale Quantum Information Technologies"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["CerQUIT"], "Technology_Description": "Our modern society and economy depend upon the constant, high-speed transmission and processing of information. Since every instance of computation or communication is realised by some physical device, it is the laws of physics that set the ultimate limits on performance. Applying this reasoning to quantum theory has led to a plethora of algorithms and protocols that achieve previously impossible levels of computational power and security. Realising the full promise of quantum information technologies will require theoretical tools, tailor-made to specific applications, which quantify the performance of a given protocol in a manner that is practical, efficient and satisfying to a sceptical end-user. This problem is particularly pressing in systems that admit a formal description only in terms of infinite dimensions. Experimental progress in such systems has shown them to be extremely promising as quantum technology platforms, but the technical difficulties in the analysis have severely constrained their application for cryptographic and information processing applications.", "To": ["2020-05-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-06-01"], "Project_ID": ["750905"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITEIT LEIDEN"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["Detection of bio-signatures in space research using a new and innovative measurement technique based on laser desorption ionisation mass spectrometry"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["BioTec"], "Technology_Description": "Detection of bio-signatures on planetary objects are of high interest for science and society. Mars is one of the most promising target in our Solar System to find traces of life. Several missions are planned in the future by, e.g., NASA and ESA to find bio-signatures on Mars. Unfortunately, since the first Viking landing on Mars in the 1970s the quest for finding bio-signatures remains unresolved. Therefore, the development of new measurement concepts for the detection of bio-signatures is of high importance for future space missions to Mars.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["750353"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Mechanobiology of the cellular circadian clock"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["MECHADIAN"], "Technology_Description": "The circadian clock is the biological mechanism that directs the physiological ~24 hour oscillations that most living organisms undergo to anticipate the daily pattern of light. In mammals, that rhythmicity results from a highly conserved genetic circuit \u2013based on transcriptional and post-transcriptional regulation\u2013 that works synchronously at a cellular level and differs among tissues. Around the 10% of the mammalian proteins, including essential components of the cell cycle and differentiation pathways have been categorised as circadian. Thus, a clock dysregulation may have pathological consequences, which is the case in some types of cancer. ", "To": ["2020-06-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2018-07-01"], "Project_ID": ["750557"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA"], "EU_Contribution": ["EUR 257 191,20"], "Project_Title": ["Developing Smart 3D Scaffolds based on Conductive Polymers and Carbon Nanotubes for Cardiac Tissue Engineering"], "Total_Cost": ["EUR 257 191,20"], "Country": ["Spain"], "Project_ACR": ["NanoBeat"], "Technology_Description": "Conductive polymers (CP) appear as promising stimulus-responsing electroactive biomaterial for profileration of cells. CP are versatile materials that can be synthesized in different shapes and morphologies, offering a wide range of application in biosensing, implants, drug delivery and tissue engineering. Carbon Nanotubes (CNTs) have become promising advanced materials and gained increasing importance for applications in nanomedicine, such as diagnosis, disease treatment, imaging, and tissue engineering. CNTs can interact with cells, cross the biological barriers, and modify their functions and biology. More recently, CNTs have become a new tool to specifically interact with the central nervous systems and support tissue repair after brain damage. Take into account of such findings, we hypothesize that CNTs exert functional effects on networks of cardiac myocytes and, in addition, the combination of those two materials will generate an outstanding scaffold for other electroactive cell growth, such as cardiac cells. In my current research, I have developed 3D scaffolds of CNT with a CP skeleton (polypyrrole or PEDOT) and, aftewards, the goal of my research and thus the aim of the current proposal is to test such scaffolds for cardiac tissue regeneration. More specific aims are: ", "To": ["2021-04-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-05-01"], "Project_ID": ["753293"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAT ROVIRA I VIRGILI", "TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY", "INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU METALE NEFEROASE SIRARE-IMNR", "POLITECHNIKA GDANSKA", "UNIVERSITAET ULM", "MOLECULAR FINGERPRINT SWEDEN AB", "SITEX 45 SRL", "JLM INNOVATION GMBH", "UNIWERSYTECKIE CENTRUM MEDYCYNY MORSKIEJ I TROPIKALNEJ"], "EU_Contribution": ["EUR 1 386 000"], "Project_Title": ["Development of a non-invassive breath test for early diagnosis of tropical diseases"], "Total_Cost": ["EUR 1 386 000"], "Country": ["Spain", "Israel", "Romania", "Poland", "Germany", "Sweden", "Romania", "Germany", "Poland"], "Project_ACR": ["TROPSENSE"], "Technology_Description": "This project aims at demonstrating the feasibility of a non-invasive, safe and patient-friendly methodology for on-site rapid diagnosis of tropical diseases. The proposed approach is based on breath samples analyses, which are easy to obtain and present no discomfort or risk for patients health. In this study will be enrolled patients with three different types of neglected tropical diseases (Hydatidosis, Leishmaniasis and Dengue) from different geographical locations (Europe, South America and Maghreb). Breath sampling will follow a standardised procedure. Analytical chemistry methods will be employed for the identification of the breath volatile biomarkers of these diseases. A pool of potential nanomaterials with high affinity towards the identified VOCs will be selected (e.g., gold nanoparticles, carbon nanotubes and semiconducting nanowires, either pristine or functionalised with selected hydrophobic organic molecules and/or bio-molecules). For maximising the possibility of success of our methodology, we will investigate the synergic effect of different advanced and complementary chemical sensing techniques: Mid-Infrared Quantum Cascade Laser spectroscopy and different types of Chemical Gas Sensors devices. These techniques are particularly attractive, since they can be miniaturised and are suitable for building on-site portable systems. Advanced pattern recognition algorithms will be employed for building discriminative models for the identification of the fingerprints of the different tropical diseases studied, and multisensors data fusion will be then applied for obtaining enhanced results. A point of care prototype will be proposed on the basis of the results obtained and validated on-site.", "To": ["2019-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2015-02-01"], "Project_ID": ["645758"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["AARHUS UNIVERSITET"], "EU_Contribution": ["EUR 212 194,80"], "Project_Title": ["Photonic-assisted Neuromorphic Computing system"], "Total_Cost": ["EUR 212 194,80"], "Country": ["Denmark"], "Project_ACR": ["PHOTON-NeuroCom"], "Technology_Description": "Neuromorphic computing has emerged as a promising approach to mimic the brain by overcoming the limitation of the conventional computers. The current implementation of neuromorphic computing systems (NCSs) has been done in CMOS technology, which comes with area and power-inefficiency. Enormous effort has been devoted to optimize the area and power-efficiency of such NCSs. One of the most promising approaches is the implementation of NCSs using spin-based devices combined with electronics (i.e. spintronics). Although, power-density is improved by spintronics-based NCSs, they are still far from the power-density of the brain that is attributed to the traditional way of changing the state of magnetic moment using a bias current that contributes to 90% of the total power consumed by such NCSs. Given a technique eliminating or decreasing this bias current, the power density of NCSs can be improved by orders of magnitude. ", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["751089"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ASTON UNIVERSITY", "ALCATEL-LUCENT DEUTSCHLAND AG", "DANMARKS TEKNISKE UNIVERSITET", "INSTITUT MINES-TELECOM", "TECHNISCHE UNIVERSITEIT DELFT"], "EU_Contribution": ["EUR 1 081 619,64"], "Project_Title": ["Fibre optic nonlinear technologies"], "Total_Cost": ["EUR 1 081 619,64"], "Country": ["United Kingdom", "Germany", "Denmark", "France", "Netherlands"], "Project_ACR": ["FONTE"], "Technology_Description": "Fibre-optic communication systems form the backbone of the world\u2019s communication infrastructure as they provide for lion fraction (more than 99%) of the global data traffic. The ongoing exponential growth in network traffic, however, is pushing current technology, whose data rates had increased over several decades, towards its limits. It is widely accepted that the nonlinear transmission effects in optical fibre are now a major limiting factor in modern fibre-optic communication systems. Nonlinear properties of the optical fibre medium limit the conventional techniques to increase capacity by simply increasing signal power. Most of the transmission technologies utilized today have been originally developed for linear (wired or wireless) communication channels. Over the past several decades, significant improvements in data rates were obtained by improvements and modifications within the overall linear transmission paradigm. However, there is much evidence that this trend is going to end within the next decade due to fibre nonlinearity. There is a clear need for radically different approaches to the coding, transmission, and processing of information that take the nonlinear properties of the optical fibre into account. This also requires education and training of a new generation of optical communication engineers and specialists with knowledge on nonlinear methods and techniques. ", "To": ["2022-05-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-06-01"], "Project_ID": ["766115"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["SYDDANSK UNIVERSITET"], "EU_Contribution": ["EUR 200 194,80"], "Project_Title": ["Breaking the Ice: INGOs as Arctic Council Observer Status Applicants"], "Total_Cost": ["EUR 200 194,80"], "Country": ["Denmark"], "Project_ACR": ["ACOSA"], "Technology_Description": "In international politics, the Arctic has emerged as one of the hottest geo-political arenas for international non-governmental organization (INGO) work in the 21st century. One of the big attractions for INGOs has been the leading regional forum, the Arctic Council, which has integrated a way for INGOs to be included into Arctic regional environmental protection and economic development discussions. This role is called \u2018observer status\u2019 and INGOs can apply for, and potentially obtain, observer status within the forum which gives them some degree of access to political discussions as they are unfolding and the political and bureaucratic elite operating on the front line of regional discussions and treaties. ", "To": ["2020-02-29, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["746312"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["INSTITUT POLYTECHNIQUE DE GRENOBLE"], "EU_Contribution": ["EUR 123 384"], "Project_Title": ["Deep understanding and modelling of the hierarchical structure of Prosody"], "Total_Cost": ["EUR 123 384"], "Country": ["France"], "Project_ACR": ["ProsoDeep"], "Technology_Description": "The prime objective of the ProsoDeep project is to gain a deeper understanding of the language of prosody through the analysis of all the levels in the production hierarchy of prosody. In particular, it will exploit the benefits of the top-down and bottom-up approaches through their incorporation within a Deep Prosody Model (DPM). The DPM will facilitate the advancement of speech technologies that rely both on the synthesis of prosody, e.g. text-to-speech (TTS) systems, and its analysis, e.g. speech emotion recognition (SER). To reach this objective the project will draw on a variety of scientific fields, including signal processing, physiology of prosody production and biomechanics, linguistics, and machine learning, and will also be augmented with respiratory measurements.", "To": ["2019-01-17, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-18"], "Project_ID": ["745802"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Superlattices and proximity effects in 2D materials/molecules hybrid van der Waals heterostructures"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["SUPER2D"], "Technology_Description": "Van der Waals heterostructures, in which graphene and related 2D materials are mechanically superimposed in a stacked structure, represent a versatile platform to obtain materials with unique properties. These artificially-assembled materials will revolutionize a number of research fields directly linked to applications, such as information and communication, and ultimately everyday life. In this context, molecules are particularly attractive, since the almost-unlimited degrees of freedom in chemical design offer the possibility to confer ad-hoc functionalities to 2D materials, paving the way to novel and unexplored areas of physics and materials science.", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-11-01"], "Project_ID": ["748971"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITETET I BERGEN"], "EU_Contribution": ["EUR 208 400,40"], "Project_Title": ["Enhancing Seafood Ethics and Sustainability: A Values and Ecosystem-based Management Approach"], "Total_Cost": ["EUR 208 400,40"], "Country": ["Norway"], "Project_ACR": ["eSEAS"], "Technology_Description": "This project aims to explore new ways of securing seafood sustainability by embedding ethics and values in the management framework. In resource management and governance the explicit articulation of values is missing. Values can aid decision-makers in resolving inherent policy trade-offs that emerge at the science-policy nexus. This will facilitate more transparent, accountable, and inclusive public decision-making. eSEAS\u2019 objectives are threefold: a. to promote cutting-edge, interdisciplinary research in the nascent field of seafood ethics; b. to develop three innovative multidisciplinary \u201cfit-for-purpose\u201d decision-support tools to enhance seafood ethics and sustainability; and c. to implement ethical approaches to European management challenges, including the complex multijurisdictional Norwegian-spring spawning and North Sea herring fisheries. The eSEAS action consists of five integrated research and training activities: 1. to define seafood ethics in relation to marine resource sustainability, policy, and governance within a post-normal science approach; 2. to develop an integrated ethical triage approach to assess sustainability with ethical indicators and test it for the balanced harvesting approach; 3. to conduct value chain analyses of European case studies, in response to consumer demand for ethical seafood; 4. to refine the values- and ecosystem-based management approach (VEBMA) I developed by incorporating a robust knowledge quality assessment and a game-theoretical / agent-based modelling approach to search for stable equilibria given stakeholder preferences; and 5. to introduce an ethical approach and apply aspects of the refined VEBMA to the NSS and North Sea herring fisheries management at ICES participatory workshops. Through public engagement and dissemination, eSEAS will catalyze a science-society dialogue and collective actions to enhance seafood ethics and sustainability.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["753937"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FRIEDRICH-SCHILLER-UNIVERSITAT JENA"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Exciton-Phonon Coupling from First Principles"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["EXPHON"], "Technology_Description": "Optical properties of materials are most relevant for a large variety of technological applications, ranging from photovoltaics over various spectroscopy techniques to LEDs and displays. In optical spectra, microscopic quantum many-body effects like excitons, i.e. coupled electron-hole-pair excitations, are measurable at a macroscopic scale and crucially determine the materials properties. Hence, a deep understanding of excitons constitutes an indispensable driving force for innovation in optics and optoelectronics.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["751823"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAET BERN", "BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE"], "EU_Contribution": ["EUR 247 840,20"], "Project_Title": ["Patient-specific tumour growth model for quantification of mechanical 'markers' in malignant gliomas: Implications for treatment outcomes."], "Total_Cost": ["EUR 247 840,20"], "Country": ["Switzerland", "United States"], "Project_ACR": ["GlimS"], "Technology_Description": "Gliomas are the most frequent primary brain tumours in adults (70%) with Glioblastoma multiforme (GBM) being the most frequent and most malignant sub-type (about 50%). Their growth is characterised by infiltration of surrounding healthy tissue, rapid proliferation, and the formation of a necrotic core. GBM growth often creates biomechanical forces that cause compression and displacement of the surrounding brain tissue. This mass-effect is of direct clinical importance; it correlates to functional loss and pressure-induced brain herniation is the leading cause of death for 73% of patients, however this is not used to inform treament. Overall long term prognosis for GBM remains poor, with median overall-survival below 1.5 years and 5-y survival rates below 3%.", "To": ["2020-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Other"], "From": ["2017-06-01"], "Project_ID": ["753878"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN"], "EU_Contribution": ["EUR 175 866"], "Project_Title": ["Excited and exotic hadron resonances from Quantum Chromodynamics"], "Total_Cost": ["EUR 175 866"], "Country": ["Ireland"], "Project_ACR": ["XXQCD"], "Technology_Description": "This project will investigate the newly observed and poorly-understood `XYZ' resonances seen in the spectrum of charmonium resonances around the open-charm threshold. These states are difficult to explain in a simple quark model and a full understanding of their nature requires lattice quantum chromodynamics to provide an ab-initio framework. One important candidate to describe some of these states is a tetraquark configuration of a bound charm quark and anti-quark coupled non-trivially to a light quark and anti-quark. The technical expertise to perform these lattice calculations has only recently been developed and it will be tested and extended in this collaborative project by combining the expertise of the fellow and the PI. ", "To": ["2019-06-29, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-30"], "Project_ID": ["749850"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FRIEDRICH-SCHILLER-UNIVERSITAT JENA"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["\u201cThinking in Images. Herder\u2019s Adrastea from 1801-03 up to nowadays\u201d"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["TIM-Adrastea"], "Technology_Description": "The research project \u201cThinking in Images. Herder\u2019s Adrastea from 1801-03 up to today\u201d will focus on the notion of thinking in images, which has a non-marginal position in the history of philosophy and science. Thinking in images means to refer, at the same time, to a complex system of forms and meanings, which continually changes itself and never follows a time sequence or a causal order. This is what distinguishes this special form of thinking from the logical sequence, from the reasoning by concepts. Analogies, metaphors, myths are only few examples of the way this \u2018visual representation\u2019 works. Such a kind of thinking characterises the children\u2019s thought, mnemonic processes, dreams, mental illnesses, hallucinations; but also, it is possible to find it in the poetry, in mythologies and religions, in mystical visions, as well as in scientific visualisations and in the arts. We will try in this study to clarify the concept of thinking in images and to highlight its value within society and culture. The starting point of the research is one of the most significant authors in the history of philosophy and culture, J.G. HERDER (1744-1803). The researcher\u2019s aim will be to make an Italian translation and a critical edition of the Adrastea (1801-1803), the last and most neglected of HERDER\u2019s works. The researcher will show the importance of this work as regards the author\u2019s position about this topic, thinking in images and will prepare a monography. HERDER edited this magazine the last years of his life and conceived it as a kind of fragmentary encyclopaedia, touching many aspects of the cultural life of his time (from politics to religion, from philosophy to science, from literature and music to esotericism and mystics). From this starting point, researcher will be able to start a multidisciplinary discussion on the topic through the organisation of seminars, workshop and international conferences with the involvement of scholars of different fields of research.", "To": ["2019-03-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-03-15"], "Project_ID": ["753540"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["MOSAIQUES DIAGNOSTICS GMBH"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Molecular profiling of Bladder Cancer to support personalized medicine"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["BioMedBC"], "Technology_Description": "BioMedBC Proposal is focused on improving the patient management of Bladder Cancer (BC). BC presents with the highest recurrence rate and the highest associated costs of all cancers. Due to the intrinsic heterogeneity, the investigated drugs in clinical trials, cannot be easily introduced in the clinical practice. Molecular profiles/ biomarkers (BM) with predictive potential are required to enable patient stratification. The BioMedBC proposal aims at the application of systems biology and cross-omics data integration methodologies to achieve: a) the molecular characterization of BC and b) develop signatures to predict the clinical outcome. To achieve these goals, integration of: i) high resolution proteomics datasets (planned to be acquired within BioMedBC), ii) existing datasets that were obtained in previous EU collaborative projects and iii) publicly available transcriptomics data, will be conducted, focusing on the molecular characterization of BC. Emphasis is given on the investigation of disease prognosis. For this purpose, clinical and follow-up data, available from ongoing prospective studies (n=1758), will be utilized for correlation analysis of the molecular profiles/ biomarkers with disease outcome (recurrence, progression and survival). The prognostic value will be confirmed in newly collected samples with emphasis placed on urinary protein/ peptide profiles, as non-invasive urinary markers is of significant added value. The innovation is held on the prognostic BM that can be further used to stratify patients to those that could be benefited by a potential intervention and guide personalized therapy to improve BC patient management. In parallel, BioMedBC aims at expanding upon the current training of the ER, Dr. Maria Frantzi, on transferability of the basic research results to clinically useful products and create strong career prospects for her desired development as an owner of a future SME.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-SE - Society and Enterprise panel"], "Coordinated_in": ["Germany"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-04-01"], "Project_ID": ["752755"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE MANCHESTER METROPOLITAN UNIVERSITY"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Multi-modal Approaches for Treatment and Evaluation of Swallowing Insufficiencies"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["MATESI"], "Technology_Description": "Human survival is dependent on swallowing because it underpins oral nutrition (eating/drinking) and protection of the respiratory tract. Swallowing difficulties (dysphagia) are a common consequence of a wide range of disorders (eg. stroke, head & neck cancers, ageing) with the results (dehydration/malnutrition/weight loss/increased susceptibility to pneumonia) linked to significant decline in quality of life. There is significant need to improve diagnosis, monitoring and rehabilitation (eg. by developing novel stimulation devices). However, existing gaps in understanding of the co-ordination of muscle activity significantly limit current advances.", "To": ["2020-08-19, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-08-20"], "Project_ID": ["749978"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAT TRIER"], "EU_Contribution": ["EUR 171 000"], "Project_Title": ["City Campus meets Illuminale 2016 / 2017"], "Total_Cost": ["EUR 386 750"], "Country": ["Germany"], "Project_ACR": ["Brainwaves"], "Technology_Description": "With the slogan \u201cBrainwaves\u201d the Researchers\u2019 Night in Trier \u2013 City Campus meets Illuminale\u2013 will be showing that science is for everyone. There is a researcher in all of us. You only need a clever mind and a lot of curiosity. Our aim is to organize a public event showing on the one hand the exciting, interesting side of science and on the other hand how science can improve the citizens' everyday life. Another main target is to enhance public recognition of researchers and their role in society. Practical results of research will be delivered in a comprehensive and illustrative form, showing that science is all around us. To simulate everyday life situations the City Campus is grouped into seven Science Sceneries in the heart of the City. In these Sceneries different research presentation formats will be organized, using new formats of knowledge transfer. To bring science and researchers into peoples\u2019 everyday life, the Sceneries will take place in unusual settings representing peoples\u2019 normal life, e.g. the Science market place with Stage and European Corner, the Scientific Theatre and the area \u201cScience goes to school\u201d. The City Campus program includes hands on experiments and demonstrations, shows, contests, quizzes, exhibitions and much more. A significant number of researchers will participate in public events to interact face-to-face with the public. The visitors \u2013 mobilized through an extensive awareness campaign \u2013 will be given the chance to touch, feel and smell science. To increase the attractiveness the effective event Illuminale will be integrated in the European Researchers\u2019 Night. Artistic illuminations of buildings and places will be combined with interesting spotlights on several areas of research. These spotlights are a metaphor for science and knowledge. Partners are the Trier University of Applied Sciences, the ttm trier Tourismus & Marketing GmbH and the Municipality of Trier.", "To": ["2017-11-30, closed project |"], "Meta": [""], "Topic_s": ["MSCA-NIGHT-2016 - European Researchers' Night"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-04-01"], "Project_ID": ["722955"], "Call_for_Proposal": ["H2020-MSCA-NIGHT-2016"]}, -{"Partners": ["IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE"], "EU_Contribution": ["EUR 2 351 550"], "Project_Title": ["Designing Conjugated Polymers for Photocatalysis and Ion Transport"], "Total_Cost": ["EUR 2 351 550"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["CAPaCITy"], "Technology_Description": "Solar energy conversion will play an essential role in the future supply of clean energy. Secure access to energy sources will require energy conversion technologies that are low impact, distributed and accessible both technically and financially. Molecular electronic materials embody these possibilities, offering facile synthesis, low energy production and the versatility to allow performance to be maximized for specific applications. Moreover, they bring appealing similarities with nature\u2019s intrinsically low impact energy conversion materials. Whilst molecular semiconductors have been studied in detail for solar-to-electric energy conversion they have seldom been studied for solar-to-chemical conversion or for charge storage. However, they bring exciting potential advantages in terms of their light harvesting properties, the range of microstructures possible and the ability to tune their electrical properties. Polymer materials applied to solar chemical generation could open up an innovative route to artificial fuels, with the option to control light harvesting and charge separation through structural control. Polymer materials applied to mixed (electronic / ionic) conduction provide a route to lower cost electrochemical storage, as well as to biocompatible devices and sensors. Stimulated by recent experimental breakthroughs in the application of polymers as photocatalysts and ion transport media I will exploit my expertise in multi-scale modelling and functional characterization of molecular electronic materials and devices to develop a design framework for energy conversion and storage in conjugated polymer materials. This proposal aims to disentangle the parameters that govern the performance of conjugated polymer based photocatalysts and ion transport media to discover the underlying functional mechanisms. The tools generated will serve to enable the design and development of high performance materials for energy conversion devices.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["742708"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITAET BERN"], "EU_Contribution": ["EUR 175 419,60"], "Project_Title": ["Exploiting carbohydrate/N-heterocyclic carbene hybrid complexes as innovative multifunctional oxidation catalysts with tailoring of weak interactions allowing for development of enzyme mimics"], "Total_Cost": ["EUR 175 419,60"], "Country": ["Switzerland"], "Project_ACR": ["GLYCONHC"], "Technology_Description": "The key objective of this project is the development of innovative hybrid complexes for oxidative catalysis of pharmaceutically relevant functional groups (e.g. alcohols, amines, olefins), by combining the beneficial properties of triazolylidine N-heterocyclic carbenes and carbohydrates for synergistic catalysis and molecular recognition, ensuring site-specific bind making and breaking processes and tailored delivery. A range of novel carbohydrate-functionalised NHC complexes (e.g. with Ru(II) and Ir(III)) will be synthesised for these purposes and relationships between carbohydrate structure/geometry and catalytic activity probed, complementing experimental approaches with computational insight.", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-03-01"], "Project_ID": ["749549"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAET BERN"], "EU_Contribution": ["EUR 187 419,60"], "Project_Title": ["Dissecting Rho GTPase signalling networks through acute perturbation techniques"], "Total_Cost": ["EUR 187 419,60"], "Country": ["Switzerland"], "Project_ACR": ["RhoSNATCH"], "Technology_Description": "Recent advances in technologies to measure Rho GTPase signaling with unprecedented spatiotemporal resolution in single living cells have led to novel questions. Important new insights are that Rho GTPase signaling involves the formation of signaling complexes that fluctuate on subminute time and micrometer length scales, and that complex signaling networks involving multiple Rho GTPases fine tune the leading edge dynamics that power fibroblast migration. Novel methodologies are required to dissect this newly discovered signaling complexity. RhoSNATCH aims to characterize these signaling networks by acutely perturbing and recording Rho GTPase signaling at biologically relevant timescales in live-cell imaging experiments of cell migration. I will identify the crosstalk between Rac1/RhoA/Cdc42 that positions and maintains specific Rho GTPase activity zones in time and space and identify dedicated functional signaling modules that fine tune specific cytoskeletal output at the leading edge of motile fibroblasts. ", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["747242"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ECOLE NORMALE SUPERIEURE", "ECOLE NORMALE SUPERIEURE"], "EU_Contribution": ["EUR 149 780"], "Project_Title": ["BabyMinder: Automatic diagnosis of neurocognitive impairment in infants"], "Total_Cost": ["EUR 149 780"], "Country": ["France", "France"], "Project_ACR": ["BabyMinder"], "Technology_Description": "Each year, millions of infants are born with neurodevelopment disorders resulting in cognitive deficits. Although infants are tested for their low-level (visual and auditory) abilities in the health care system, no standard tools exist for evaluating the development of cognitive functions, due to the absence of verbal report and explicit behaviour. Converging evidence now suggests that neural markers obtained from electroencephalographic (EEG) offer a valid approach for tracking the development of cognitive functions in the infant brain. The BabyMinder provides a proof-of-concept for a novel EEG portable system combined with a sensory stimulation application to track normal and impaired neurocognitive processing in infants. Its main purpose will be to help the diagnosis of neurodevelopmental disorders. The BabyMinder will be fully embedded in a wearable system and will feature active electrodes, which provide reliable EEG signals, yet do not require any electrolyte gel or humidification. Although several low-cost and fully portable systems have recently been developed for adults, none of these portable systems has been adapted to infant populations. It will also consist of a functional localizer for the automatic tracking of neurocognitive components. This functional localizer will consist of a stimulation protocol with various types of stimuli presented every few seconds, tapping specific levels of representation while the EEG device will monitor the deployment of dedicated neurocognitive components in real-time. The whole procedure will be embedded in children-friendly animations to keep infants interested. In time, a large database of participants will be collected and combined with state-of-the-art machine learning algorithms using a big data approach, improving the classification of normal vs. impaired neurocognitive processes. We aim to make the BabyMinder a standard tool for the diagnosis of neurodevelopmental disorders in the future.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["768527"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG", "RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Encapsulated eukaryotic ribosome assembly"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["Glowsome"], "Technology_Description": "The production of fully functional ribosomes is vital for every cell, with failure causing human diseases called ribosomopathies. Eukaryotic ribosome assembly is catalyzed by ~200 assembly factors that guarantee efficient and accurate production of ribosomal subunits along a temporally and spatially ordered pathway. About one third of these factors are utilized in the formation of the earliest biogenesis intermediate, termed 90S pre-ribosome or small subunit processome. Recent insight into the 90S structure from a eukaryotic thermophile, Chaetomium thermophilum, has provided a first spatial impression on this most sophisticated process, which includes co-transcriptional RNA folding and processing, and incorporation of ribosomal proteins. Our key discovery was that the nascent ribosomal RNA, which if linear would form a long thread, is co-transcriptionally mounted into a mold formed by a highly interconnected RNA-protein scaffold on the 90S pre-ribosome. This finding raises a novel concept in RNA biology that nascent RNA folds and matures in a protected environment, which is reminiscent of protein folding that can also occur in folding chambers. I plan to challenge the idea that the 90S particle indeed encapsulates the RNA transiently, in order to protect it from unproductive interactions, allowing stepwise folding and maturation in a cascade of interdependent reactions and the involvement of energy-consuming enzymes. The groundbreaking aim of this proposal is to decipher how these processes occur in an encapsulated environment, using C. thermophilum as a model organism. This high-risk project will depend on the successful establishment of novel assays that recapitulate eukaryotic ribosome assembly in vitro, exploiting the thermostable nature of the 90S pre-ribosome. Mechanistic insight into ribosome biogenesis will lead to a better understanding of how this multifaceted process is linked to other key cellular pathways and development of diseases including cancer.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["741781"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["KARLSRUHER INSTITUT FUER TECHNOLOGIE", "KARLSRUHER INSTITUT FUER TECHNOLOGIE"], "EU_Contribution": ["EUR 2 499 981"], "Project_Title": ["Multidimensional CRISPR/Cas mediated engineering of plant breeding"], "Total_Cost": ["EUR 2 499 981,27"], "Country": ["Germany", "Germany"], "Project_ACR": ["CRISBREED"], "Technology_Description": "The implementation of CRISPR/Cas technology has already revolutionised biology and biotechnology. However, for plant breeding its full potential has hardly been applied. The gene pool of a plant species carries a tremendous amount of information regarding how to survive best under various biotic and abiotic stresses. Although countless wild varieties of crops have been safeguarded in gene banks worldwide, much of their genetic information cannot be used in agriculture. Often, adverse and/or favourite traits are linked due to the fact that respective genes are located within close proximity, on the same chromosome. Breeding aims not only to break linkages between such traits but also to tightly fix favourable linkages. In cereals, half of the genome cannot be accessed by classical breeding. The aim of this proposal is to develop techniques based on CRISPR/Cas technology, to engineer plant breeding on the molecular level. With the use of the Cas9 nuclease of S. pyogenes and multiple sgRNAs, it became possible to induce several genomic changes at the same time. The aim of this proposal is to perform genome engineering on a multidimensional level by not only inducing multiple DNA lesions (single and double stranded breaks) but also by applying different Cas9 orthologues to simultaneously target DNA recombination factors directly to the sites of action, or indirectly by influencing their expression. Thus, site-specific initiation of recombination should be coupled with pathway choice, resulting in novel approaches for breaking or fixing linkages. Techniques for genome restructuring, like inversions and translocations, should be established as well as efficient induction of somatic and meiotic crossovers. Therefore, the basis should be laid for combining the best available traits of a species, resulting in transgene free crop plants for a sustainable agriculture. Furthermore, the Cas9-controlled transfer of chromosomal segments between species will also be addressed.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["741306"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION", "FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION"], "EU_Contribution": ["EUR 2 358 625"], "Project_Title": ["Cyclical and Linear Timing Modes in Development"], "Total_Cost": ["EUR 2 358 625"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["CYCLODE"], "Technology_Description": "Organismal development requires proper timing of events such as cell fate choices, but the mechanisms that control temporal patterning remain poorly understood. In particular, we know little of the cyclical timers, or \u2018clocks\u2019, that control recurring events such as vertebrate segmentation or nematode molting. Furthermore, it is unknown how cyclical timers are coordinated with the global, or linear, timing of development, e.g. to ensure an appropriate number of cyclical repeats. We propose to elucidate the components, wiring, and properties of a prototypic developmental clock by studying developmental timing in the roundworm C. elegans. We build on our recent discovery that nearly 20% of the worm\u2019s transcriptome oscillates during larval development \u2013 an apparent manifestation of a clock that times the various recurring events that encompass each larval stage. Our aims are i) to identify components of this clock using genetic screens, ii) to gain insight into the system\u2019s architecture and properties by employing specific perturbations such as food deprivation, and iii) to understand the coupling of this cyclic clock to the linear heterochronic timer through genetic manipulations. To achieve our ambitious goals, we will develop tools for mRNA sequencing of individual worms and for their developmental tracking and microchamber-based imaging. These important advances will increase temporal resolution, enhance signal-to-noise ratio, and achieve live tracking of oscillations in vivo. Our combination of genetic, genomic, imaging, and computational approaches will provide a detailed understanding of this clock, and biological timing mechanisms in general. As heterochronic genes and rhythmic gene expression are also important for controlling stem cell fates, we foresee that the results gained will additionally reveal regulatory mechanisms of stem cells, thus advancing our fundamental understanding of animal development and future applications in regenerative medicine.\u2028", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-10-01"], "Project_ID": ["741269"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITAET KLAGENFURT", "UNIVERSITAET KLAGENFURT", "HUMBOLDT-UNIVERSITAET ZU BERLIN"], "EU_Contribution": ["EUR 2 483 686"], "Project_Title": ["Understanding the Role of Material Stock Patterns for the Transformation to a Sustainable Society"], "Total_Cost": ["EUR 2 483 686,06"], "Country": ["Austria", "Austria", "Germany"], "Project_ACR": ["MAT_STOCKS"], "Technology_Description": "Sustainability transformations imply fundamental changes in the societal use of biophysical resources. Current socioeconomic metabolism research traces flows of energy, materials or substances to capture resource use: input of raw materials or energy, their fate in production and consumption, and the discharge of wastes and emissions. This approach has yielded important insights into eco-efficiency and long-term drivers of resource use. But due to its focus on flows, socio-metabolic research has not yet incorporated material stocks or their services, thereby not fully realizing its analytic potential. MAT_STOCKS addresses this gap by developing a consistent typology, indicators and databases of material stocks and their services, building upon economy-wide material flow analysis. It will create a comprehensive, global, national-level, validated material stocks and services database as well as maps of material stocks from remote-sensing data. This will allow analyzing the stock/flow/service nexus and underpin highly innovative indicators of eco-efficiency overcoming limitations of current approaches which mainly relate resource use or emissions to population and GDP. New insights on stock/flow/service relations, the relevance of spatial patterns and options for decoupling will be used to create a dynamic model to assess option spaces for transformations towards sustainable metabolism. MAT_STOCKS will identify barriers and leverage points for future sustainability transformations and the SDGs, and elucidate their socio-ecological and political implications. Our preliminary analyses suggest that unravelling the stock/flow/service nexus provides a crucial missing link in socio-metabolic research because it explains why, how and where patterns of material and energy use change or remain locked-in. Thereby, important analytical insights will be introduced into the largely normative and local discourses on the transformation towards a sustainable society.", "To": ["2023-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["741950"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["TECHNISCHE UNIVERSITEIT EINDHOVEN", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "FRIEDRICH-SCHILLER-UNIVERSITAT JENA", "UNIVERSITAT LINZ", "IBM RESEARCH GMBH", "TECHNISCHE UNIVERSITAET MUENCHEN"], "EU_Contribution": ["EUR 3 985 417,50"], "Project_Title": ["SiliconLaser"], "Total_Cost": ["EUR 3 985 418,75"], "Country": ["Netherlands", "United Kingdom", "Germany", "Austria", "Switzerland", "Germany"], "Project_ACR": ["SiLAS"], "Technology_Description": "Our research aims to revolutionize the electronics industry by adding intra-chip and chip-to-chip communication at the speed of light, offering a significantly reduced energy consumption. Cubic crystal phase SiGe is known to be great for electronics. We propose to develop hexagonal crystal phase SiGe (Hex-SiGe) which features a direct bandgap and will add photonic capabilities to electronics. Direct bandgap silicon has been the holy grail of the semiconductor industry for many years, since it would allow integrating both electronic and optical functionalities on a silicon platform. Recent theoretical calculations predict that hexagonal crystal phase SixGe1-x features a tunable direct bandgap from 1380-1800 nm, exactly coinciding with the low loss window for optical fibre communications. We have recently developed a generic approach to grow defect-free hexagonal SixGe1-x with tunable composition. We propose to demonstrate efficient light emission from direct bandgap SiGe, followed by the development of a SiGe nanolaser. Work towards CMOS integration is included. The demonstration of a Hex-SiGe nanolaser will serve as a game-changer for transforming the electronics industry.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-01-2016-2017 - FET-Open research and innovation actions"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["735008"], "Call_for_Proposal": ["H2020-FETOPEN-1-2016-2017"]}, -{"Partners": ["FORSCHUNGSINSTITUT FUR MOLEKULARE PATHOLOGIE GESELLSCHAFT MBH", "FORSCHUNGSINSTITUT FUR MOLEKULARE PATHOLOGIE GESELLSCHAFT MBH"], "EU_Contribution": ["EUR 2 500 000"], "Project_Title": ["Transcriptional control of plasma cell development and function"], "Total_Cost": ["EUR 2 500 000"], "Country": ["Austria", "Austria"], "Project_ACR": ["PlasmaCellControl"], "Technology_Description": "Antibody-secreting cells consisting of short-lived proliferating plasmablasts and long-lived quiescent plasma cells are essential for the acute response to infection and long-term protection of the host against pathogens. Only a few regulators (Blimp1, IRF4, XBP1, Aiolos, Ikaros and E-proteins) have been implicated in the transcriptional control of antibody-secreting cells, and their target genes, with the exception of Blimp1 and E-proteins, are still unknown. This proposal aims to systematically identify key players in the development and function of antibody-secreting cells by using the CRISPR/Cas9 and Cre/loxP methods.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Austria"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-01-01"], "Project_ID": ["740349"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITY OF LEEDS", "UNIVERSITY OF LEEDS"], "EU_Contribution": ["EUR 2 271 830"], "Project_Title": ["Intelligent corrosion management underpinned by advanced engineering science"], "Total_Cost": ["EUR 2 271 830"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["INTELLICORR"], "Technology_Description": "Our planet\u2019s population will continue to grow rapidly; between 2010 and 2025 the population will grow by 1.1bn. Urbanisation and growth of the consumer class in developing countries will lead to unprecedented demands on energy. There is arguably no bigger challenge to society than ensuring the security of affordable and environmentally-sustainable energy. ", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["742930"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITAET LEIPZIG", "UNIVERSITAET LEIPZIG"], "EU_Contribution": ["EUR 2 379 250"], "Project_Title": ["What Holds Cancer Cells Back?"], "Total_Cost": ["EUR 2 379 250"], "Country": ["Germany", "Germany"], "Project_ACR": ["HoldCancerBack"], "Technology_Description": "Since decades the bulk of cancer research focusses on the genetic and molecular level. To complement this knowledge, I will focus on the collective behaviour of cancer cells in cell clusters and in the extracellular matrix (ECM).", "To": ["2022-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["741350"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITAET BERN", "UNIVERSITAET BERN"], "EU_Contribution": ["EUR 1 493 736"], "Project_Title": ["Neuronal circuits for emotions in the ventral CA1 hippocampus"], "Total_Cost": ["EUR 1 493 736"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["ventralHippocampus"], "Technology_Description": "A fundamental objective in modern neurosciences is to understand the neural mechanisms of learning and memory in both healthy and pathological conditions. The hippocampus is a high-order cortical brain region important for emotions and cognition. The ventral subdivision of the hippocampus (anterior hippocampus in primates) is mostly involved in anxiety and contextual fear conditioning behaviours. ", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["716761"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["UNIVERSITAET SIEGEN", "UNIVERSITAT TRIER", "LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN", "SWANSEA UNIVERSITY", "THE UNIVERSITY OF BIRMINGHAM", "INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE", "UNIVERZA V LJUBLJANI", "UNIVERSITEIT MAASTRICHT", "STOCKHOLMS UNIVERSITET", "UNIVERSITA DEGLI STUDI DI PADOVA", "UNIVERSIDADE DO ALGARVE", "ASTON UNIVERSITY", "Fachhochschule Dortmund"], "EU_Contribution": ["EUR 958 500"], "Project_Title": ["Computing with Infinite Data"], "Total_Cost": ["EUR 1 462 500"], "Country": ["Germany", "Germany", "Germany", "United Kingdom", "United Kingdom", "France", "Slovenia", "Netherlands", "Sweden", "Italy", "Portugal", "United Kingdom", "Germany"], "Project_ACR": ["CID"], "Technology_Description": "The joint research in this programme will study important aspects\u2014both theoretical as well as applied\u2014of computing with infinite objects. A central aim is laying the grounds for the generation of efficient and verified software in engineering applications. ", "To": ["2021-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["731143"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "KOBENHAVNS UNIVERSITET", "FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG", "AALTO-KORKEAKOULUSAATIO", "UNIVERSITA DEGLI STUDI DI CAMERINO", "UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6", "UNIVERSITAT WIEN", "UNIVERSITAET HAMBURG", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSITAT KONSTANZ", "UNIVERSITEIT GENT", "TECHNISCHE UNIVERSITEIT DELFT", "IBM RESEARCH GMBH", "ROBERT BOSCH GMBH"], "EU_Contribution": ["EUR 3 897 454,32"], "Project_Title": ["OMT - Optomechanical Technologies"], "Total_Cost": ["EUR 3 897 454,32"], "Country": ["Switzerland", "Denmark", "Germany", "Finland", "Italy", "France", "Austria", "Germany", "France", "Germany", "Belgium", "Netherlands", "Switzerland", "Germany"], "Project_ACR": ["OMT"], "Technology_Description": "The proposed project is built on the successful training and research experience of the leading European research groups working in the field of cavity optomechanics. Our ENT unites a total of 14 leading groups in the field, of which two are major industrial players that utilize MEMS and NEMS - Bosch and IBM. The main goal of the project is to exploit optomechanical interactions in views of novel functionality and possible applications of cavity optomechanical systems that were envisioned by consortium partners during their previous research activities. ", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-10-01"], "Project_ID": ["722923"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["FUNDACION CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III", "ACQUIFER AG", "Leica Microsystems CMS GmbH", "CENTRE EUROPEEN DE RECHERCHE EN BIOLOGIE ET MEDECINE", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSITAET BERN", "PHILIPS IBERICA SA"], "EU_Contribution": ["EUR 1 529 110,80"], "Project_Title": ["4D analysis of heart development and regeneration using advanced light microscopy"], "Total_Cost": ["EUR 1 529 110,80"], "Country": ["Spain", "Germany", "Germany", "France", "France", "Switzerland", "Spain"], "Project_ACR": ["4DHeart"], "Technology_Description": "Cardiovascular (CV) disease is a main cause of death worldwide. During adulthood, ischemic heart disease leads to heart failure and perinatally, congenital heart defects are found in over 20% of deaths. Moreover, genetic or epigenetic factors altering development can have an impact much later in life. These facts underscore the need of a better understanding of the genetic and environmental factors that influence CV development. An important way to increase our knowledge is by visualizing cardiac development in vivo. Recent advance in microscopy allows monitoring CV development at a cellular level in organisms such as the zebrafish model. Particularly revolutionary has been the development of light sheet microscopy (LSM). We want to further exploit LSM for in vivo manipulation of cells in the embryonic zebrafish heart and measure with high precision biophysical parameters, by introducing novel features to LSM such as optical tweezers. High throughput cardiac imaging protocols for zebrafish larvae suitable for screenings will be set up. We will develop softwares to enhance resolution of acquisition, large dataset handling and image-processing. The aim is to generate a toolbox to be implemented into existing software packages allowing a complete modeling of zebrafish cardiac morphogenesis. We will adapt LSM for adult zebrafish hearts to study cardiac regeneration and mouse heart development at cellular resolution. Each Early Stage Researchers (ESRs) will develop their own technology to solve a biological problem at the frontier of knowledge. ESRs will receive multidisciplinary (CV development, physics, biocomputing, bioimaging) as well as intersectorial (academic research, SMEs, large companies) training and will achieve unique skills on microscopy, in-vivo imaging and image analysis allowing them to interrogate questions on cardiac development and regeneration. Their profile will be at the interface of a bioengineer and a life science researcher filling a currently existing gap on the market.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["722427"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["UNIVERSITAET BERN"], "EU_Contribution": ["EUR 187 419,60"], "Project_Title": ["DNA repair mechanisms and therapy resistance of BRCA2-deficient cancers"], "Total_Cost": ["EUR 187 419,60"], "Country": ["Switzerland"], "Project_ACR": ["DREMATURE"], "Technology_Description": "Despite the existence of various novel anti-cancer treatments, drug resistance remains a major cause of death in patients with disseminated cancer. To increase specificity and efficacy, modern treatment strategies in molecular oncology employ the \u201csynthetic lethality\u201d concept. An example are BRCA1/2-deficient breast and ovarian cancers that lack DNA repair by homologous recombination (HR). Due to this defect, tumor cells rely more on other DNA repair pathways. When such alternative pathways are jammed, e.g. by poly(ADP-ribose) polymerase inhibitors (PARPi), normal cells with intact HR can survive, whereas cancer cells die. However, even with this sophisticated treatment strategy, resistance to PARPi still occurs and greatly reduces patient survival. The mechanisms driving this resistance are still largely unknown. The main goal of this project is to advance the knowledge on therapy resistance by using a genetically engineered mouse model of BRCA2-deficient breast cancer, which closely mimics the human disease. Like in patients, cancer cells in these animals eventually escape from therapy. I will start by synergizing the next generation sequencing analysis of spontaneous resistant mouse tumors with functional genetic screens using the CRISPR/Cas9 technology. This combination has yielded interesting candidate genes whose loss of function may cause resistance. Two promising candidates, MDC1 and Claspin, will be further investigated using innovative and physiologically relevant 3D tumor organoid cultures. Moreover, I will apply my expertise in modern imaging technology to develop novel approaches to visualize DNA repair dynamics in resistant tumors in vitro and in vivo. I am convinced that by understanding basic resistance mechanisms, smart biosensors can be built to image the DNA damage response and eventually improve clinical decision making. I believe this project will have an impact on the design of strategies to overcome therapy escape in human cancer patients.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["743290"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAET BERN", "UNIVERSITAET BERN"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Connectivity Correlate of Molecular Pathology in Neurodegeneration"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["ConCorND"], "Technology_Description": "Neurodegenerative diseases (NDs) are incurable, debilitating conditions, arise mid-late in life, represent an enormous health and socioeconomic burden and no therapies exist. An enigmatic finding in NDs is the early and selective alteration in intrinsic excitability of vulnerable neurons paralleling changes in its circuitry. However, a gap in understanding exists in ND field about the cause of these alterations and whether these modifications regulate degenerative pathomechanisms. Our recent study, examining mechanisms of Purkinje cell (PC) degeneration in Spinocerebellar ataxia type 1 (SCA1) revealed that the earliest cerebellar alterations occur in the major excitatory inputs onto PCs, the climbing fibers (CFs). Based on this, we propose a novel three-step model of neurodegeneration: First, suboptimal functioning of the presynaptic inputs initiates signaling deficits in target PCs. Second, those alterations trigger maladaptive responses such as altered intrinsic PC excitability, thus amplifying pathogenic cascades. Third, at network level progressive dysfunction triggers compensatory synaptic modifications within the cerebellar circuitry. In this proposal, we will test our new hypothesis for NDs on SCA1 and this will be the first study to test circuit-dependency in NDs by selectively silencing presynaptic inputs and examining molecular responses in the postsynaptic neuron. Specifically, we will 1) Identify the dysfunctional CF associated molecular signature in PCs. 2) Elucidate mechanisms involved in altering intrinsic PC excitability. 3) Map the connectome for a structural correlate of the pathology. Using conditional mouse models, pharmacogenetics, transcriptomics, proteomics and connectomics, we will delineate molecular alterations that govern disease from compensatory alterations. Our systematic approach will not only impact SCA related therapies but the entire spectrum of NDs and has the potential to change the conceptual approach of future studies on NDs.", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["725825"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["GOETEBORGS UNIVERSITET", "UPPSALA UNIVERSITET", "Asociacion - Centro de Investigacion Cooperativa en Nanociencias - CIC NANOGUNE", "UNIVERSITA DEGLI STUDI DI FIRENZE", "UNIVERSITY OF YORK", "STICHTING KATHOLIEKE UNIVERSITEIT", "PAUL SCHERRER INSTITUT", "NANOSC AB", "UNIVERSITA DI PISA", "THALES SA"], "EU_Contribution": ["EUR 3 712 832,50"], "Project_Title": ["Spinoptical nanoantenna-assisted magnetic storage at few nanometers on femtosecond timescale"], "Total_Cost": ["EUR 3 712 832,50"], "Country": ["Sweden", "Sweden", "Spain", "Italy", "United Kingdom", "Netherlands", "Switzerland", "Sweden", "Italy", "France"], "Project_ACR": ["FEMTOTERABYTE"], "Technology_Description": "We will develop the conceptually new paradigm for ultra-dense and ultrafast magnetic storage that will exceed the current technology by two orders of magnitude in storage density (going from terabit/inch2 to tens of terabytes/inch2) and by about four orders of magnitude in operation speed (going from low GHz to THz for read/write). This will be achieved in an all-optical platform that allows deterministic, non-thermal, low-energy, ultrafast magnetization switching at few nanometers and potentially down to a molecular length-scale. The main building block of the envisioned memory unit in this new paradigm is the spinoptical nanoplasmonic antenna that concentrates pulsed polarized light at the nanometer length-scale and enables non-thermal spin-orbit mediated transfer of the light\u2019s angular momentum (orbital and/or spin) to the nanoscale magnetic architectures. In this way fs-pulsed light, assisted by the plasmonic optical spin-selective antenna and the local electromagnetic field enhancement, allows for the precise control of the magnetic state of nanometer sized / molecular magnetic structures. The project aims to elucidate the fundamentals of the emergence and manipulation of light\u2019s orbital and spin angular momenta to achieve non-thermal momentum-transfer-driven ultrafast switching process, to demonstrate its practical realization, and will map its suitability for future upscaling towards industrial implementation in devices.", "To": ["2020-02-29, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-01-2016-2017 - FET-Open research and innovation actions"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-03-01"], "Project_ID": ["737093"], "Call_for_Proposal": ["H2020-FETOPEN-1-2016-2017"]}, -{"Partners": ["UPPSALA UNIVERSITET", "UPPSALA UNIVERSITET"], "EU_Contribution": ["EUR 1 610 000"], "Project_Title": ["Coordination and Composability: The Keys to Efficient Memory System Design"], "Total_Cost": ["EUR 1 610 000"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["CC-MEM"], "Technology_Description": "Computer systems today are power limited. As a result, efficiency gains can be translated into performance. Over the past decade we have been so effective at making computation more efficient that we are now at the point where we spend as much energy moving data (from memory to cache to processor) as we do computing the results. And this trend is only becoming worse as we demand more bandwidth for more powerful processors. To improve performance we need to revisit the way we design memory systems from an energy-first perspective, both at the hardware level and by coordinating data movement between hardware and software.", "To": ["2022-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-03-01"], "Project_ID": ["715283"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["UNIVERSITAET BERN", "UNIVERSITAET BERN"], "EU_Contribution": ["EUR 1 404 062"], "Project_Title": ["Unique Method for a Neutron Electric Dipole Moment Search using a Pulsed Beam"], "Total_Cost": ["EUR 1 404 062"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["BEAM-EDM"], "Technology_Description": "My research encompasses the application of novel methods and strategies in the field of low energy particle physics. The goal of the presented program is to lead an independent and highly competitive experiment to search for a CP violating neutron electric dipole moment (nEDM), as well as for new exotic interactions using highly sensitive neutron and proton spin resonance techniques.", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["715031"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH", "STIFTUNG DEUTSCHES ELEKTRONEN-SYNCHROTRON DESY", "ISTITUTO NAZIONALE DI FISICA NUCLEARE", "THE HENRYK NIEWODNICZANSKI INSTITUTE OF NUCLEAR PHYSICS, POLISH ACADEMY OF SCIENCES", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "SCIENCE AND TECHNOLOGY FACILITIES COUNCIL", "UPPSALA UNIVERSITET", "PAUL SCHERRER INSTITUT", "KARLSRUHER INSTITUT FUER TECHNOLOGIE"], "EU_Contribution": ["EUR 2 279 750"], "Project_Title": ["Accelerator and Magnet Infrastructure for Cooperation and Innovation"], "Total_Cost": ["EUR 2 279 750"], "Country": ["France", "Switzerland", "Germany", "Italy", "Poland", "France", "United Kingdom", "Sweden", "Switzerland", "Germany"], "Project_ACR": ["AMICI"], "Technology_Description": "Development and construction of accelerator based scientific Research Infrastructures are going through a deep paradigm change because of the need for large scale Technological Infrastructures at the forefront of technology to master the key accelerator and magnet science and technology needed for several fields. Indeed, because of the high technological level and of the increased size and time scale of projects, development and construction require more and more sophisticated R&D platforms on key accelerator and magnet technologies, large-scale facilities for their assembly, integration and verification, large concentrations of dedicated skilled personnel and long term relationships between laboratories and industry. In response to those challenges, a few large platforms specialized in interdisciplinary technologies and for applications of direct benefit to society are emerging. The emerging Technological Infrastructure is aiming at creating an efficient integrated ecosystem among laboratories focussed on R&D, with a long term vision for the technological needs of future RIs and industry, including SME, motivated by the innovative environment and the market created by the realisation of the technological needs of several RIs. With a timeline of 30 months, involving 10 Consortium partners, the AMICI proposal will ensure that A) a stronger and optimised integration model between the large existing technological infrastructures is developed and agreed upon, B) that this integrated ecosystem is attracting industries and fostering innovation based on accelerator and SC magnets cutting-edge developments, C) that strategy and roadmaps are clearly defined and understood to strongly position European industries and SMEs on the market of the construction of new Research Infrastructures worldwide, and D) that potential societal applications are identified and disseminated to the relevant partners of this ecosystem.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["INFRAINNOV-02-2016 - Support to Technological Infrastructures"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["731086"], "Call_for_Proposal": ["H2020-INFRAINNOV-2016-1"]}, -{"Partners": ["UPPSALA UNIVERSITET", "UPPSALA UNIVERSITET"], "EU_Contribution": ["EUR 1 494 880"], "Project_Title": ["Chemistry and Biology in Synergy - Studies of hydrogenases using a combination of synthetic chemistry and biological tools"], "Total_Cost": ["EUR 1 494 880"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["CaBiS"], "Technology_Description": "My proposal aims to take advantage of my ground-breaking finding that it is possible to mature, or activate, the [FeFe] hydrogenase enzyme (HydA) using synthetic mimics of its catalytic [2Fe] cofactor. (Berggren et al, Nature, 2013) We will now explore the chemistry and (bio-)technological potential of the enzyme using an interdisciplinary approach ranging from in vivo biochemical studies all the way to synthetic model chemistry. Hydrogenases catalyse the interconversion between protons and H2 with remarkable efficiency. Consequently, they are intensively studied as alternatives to Pt-catalysts for these reactions, and are arguably of high (bio-) technological importance in the light of a future \u201chydrogen society\u201d.", "To": ["2022-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-02-01"], "Project_ID": ["714102"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["UPPSALA UNIVERSITET", "UPPSALA UNIVERSITET"], "EU_Contribution": ["EUR 1 498 954"], "Project_Title": ["Single-Molecule And Structural Studies Of ATP-Dependent Chromatin Remodelling"], "Total_Cost": ["EUR 1 498 954"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["ChromatinRemodelling"], "Technology_Description": "The packaging of genetic information into chromatin regulates a wide range of vital processes that depend on direct access to the DNA template. Many chromatin-interacting complexes impact chromatin structure and their aberrant regulation or dysfunction has been implicated in various cancers and severe developmental disorders. A better understanding of the roles of chromatin-interacting complexes in such disease states requires a detailed mechanistic study. Many chromatin-interacting complexes modify chromatin structure, yet understanding the underlying mechanisms remains a major challenge in the field. Furthermore, how chromatin-interacting complexes are regulated to enable their various functions is incompletely understood. We will address these longstanding questions in two specific aims. Aim I: Building on our expertise in single-molecule biology, we will develop powerful single-molecule imaging approaches to monitor the action of chromatin-interacting complexes in real time. We will further probe how the diverse activities of the chromatin-associated complexes are coordinated and coupled to conformational transitions. Aim II: Drawing on our expertise in structural biology, we will use a range of structural techniques in combination with biochemical approaches to study the vital regulation of chromatin-interacting complexes by their regulatory subunits as well as by chromatin features. We expect to obtain ground-breaking insights into the mechanisms and regulation of disease-related chromatin-associated complexes, which may open up new horizons for developing therapeutic intervention strategies. Furthermore, the approaches developed here will enable the investigation of a large number of chromatin-related processes.", "To": ["2022-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-03-01"], "Project_ID": ["714068"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["UNIVERSITAET BERN", "UNIVERSITAET BERN", "UNIVERSITE DE FRIBOURG"], "EU_Contribution": ["EUR 1 498 275"], "Project_Title": ["Organic Semiconductors Interfaced with Biological Environments"], "Total_Cost": ["EUR 1 498 275"], "Country": ["Switzerland", "Switzerland", "Switzerland"], "Project_ACR": ["OSIRIS"], "Technology_Description": "Transducing information to and from biological environments is essential for bioresearch, neuroscience and healthcare. There has been recent focus on using organic semiconductors to interface the living world, since their structural similarity to bio-macromolecules strongly favours their biological integration. Either water-soluble conjugated polyelectrolytes are dissolved in the biological medium, or solid-state organic thin films are incorporated into bioelectronic devices. Proof-of-concept of versatile applications has been demonstrated \u2013 sensing, neural stimulation, transduction of brain activity, and photo-stimulation of cells. However, progress in the organic biosensing and bioelectronics field is limited by poor understanding of the underlying fundamental working principles. Given the complexity of the disordered, hybrid solid-liquid systems of interest, gaining mechanistic knowledge presents a considerable scientific challenge. The objective of OSIRIS is to overcome this challenge with a high-end spectroscopic approach, at present essentially missing from the field. We will address: 1) The nature of the interface at molecular and macroscopic level (assembly of polyelectrolytes with bio-molecules, interfacial properties of immersed organic thin films). 2) How the optoelectronics of organic semiconductors are affected upon exposure to aqueous environments containing electrolytes, biomolecules and cells. 3) How information is transduced across the interface (optical signals, thermal effects, charge transfer, electric fields, interplay of electronic/ionic transport). Via spectroscopy, we will target relevant optoelectronic processes with ultrafast time-resolution, structurally characterize the solid-liquid interface using non-linear sum-frequency generation, exploit Stark shifts related to interfacial fields, determine nanoscale charge mobility using terahertz spectroscopy in attenuated total reflection geometry, and simultaneously measure ionic transport.", "To": ["2022-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["714586"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "UPPSALA UNIVERSITET", "CENTRO DE NEUROCIENCIAS E BIOLOGIACELULAR ASSOCIACAO", "THE HEBREW UNIVERSITY OF JERUSALEM", "UNIVERZA V LJUBLJANI", "NIMGENETICS, GENOMICA Y MEDICINA S.L.", "BNML BEHAVIORAL & MOLECULAR LAB", "FUNDACION PARA LA INVESTIGACION BIOMEDICA DEL HOSPITAL UNIVERSITARIO LA PRINCESA", "CELL STRESS DISCOVERIES LIMITED"], "EU_Contribution": ["EUR 3 750 898,68"], "Project_Title": ["Training European Network: Metabolic Dysfunctions associated with Pharmacological Treatment of Schizophrenia"], "Total_Cost": ["EUR 3 750 898,68"], "Country": ["Spain", "Sweden", "Portugal", "Israel", "Slovenia", "Spain", "Portugal", "Spain", "Ireland"], "Project_ACR": ["TREATMENT"], "Technology_Description": "TREATMENT is a Marie Sklodowska Curie Innovative Training Network proposal directly addressing the need for high-level training and career paths in risk evaluation of drug induced metabolic dysfunctions, a relevant aspect, so far unexplored by traditional toxicology studies, but urgently needed to challenge current severe limitations of health care interventions in mental disorders. These patients require life-long medications that subsequently trigger metabolic diseases with a strong negative impact on their health and well-being. To achieve this, and improve adherence to treatments, we will evaluate how short-term antipsychotic drug responses impact long-term metabolic control to identify and validate biomarkers with clinically predictive value for targeting drug induced metabolic dysfunctions. This effort will have added commercial value by enabling the design of predictive marker kits for testing adverse secondary metabolic effects of drugs to be used in pharmacological and medical practice. TREATMENT will provide multidisciplinary knowledge, capabilities and tools to implement this ambitious strategy by the training of young scientists in a program that combines pharmacology, metabolism and mental health research with strategies for product and tool design and validation. Our ultimate goal is to empower the intersectorial and trans-national employability of young scientists across academic, public and private sectors to foster the development and implementation of personalized medicine tools that will provide effective treatment regimens for life long health-care interventions and decrease the risk for development of chronic metabolic diseases.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["721236"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["UPPSALA UNIVERSITET"], "EU_Contribution": ["EUR 185 857,20"], "Project_Title": ["Towards an Inclusive Common European Framework for Assisted Reproductive Technologies (ART): Queer Transgender Reproduction in the Age of ART."], "Total_Cost": ["EUR 185 857,20"], "Country": ["Sweden"], "Project_ACR": ["QTReproART"], "Technology_Description": "The use and regulation of Assisted Reproductive Technologies (ARTs) has undergone repeated significant changes since the 1980s, partly to accommodate biotechnological developments, partly to recognize shifts in socio-cultural practices of kinship and family. These changes have generally been towards greater inclusivity but have been variedly legislated and implemented in the diverse European countries, leading to \u2018reproductive migration\u2019. As the numbers of ART users and clinics rise, there is a clear need to provide a common European framework for ART: this is the purpose of this project.", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["749218"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAT ZURICH"], "EU_Contribution": ["EUR 187 419,60"], "Project_Title": ["\u201cFINancial and REAL Sector NETworks in Europe\u201d"], "Total_Cost": ["EUR 187 419,60"], "Country": ["Switzerland"], "Project_ACR": ["FINREALNETS"], "Technology_Description": "Banks\u2019 exposures to similar asset groups could become an important source of contagion when combined with interbank network spillovers. The FINREALNET project aims at elaborating a common portfolio network-based stress-test framework that could find application in regular stress-testing exercises carried out by the regulator. Using an innovative DebtRank-based model FINREALNET suggests identifying Systemically Important Real Sectors (SIRS) at the euro area and test stabilizing effects of sector targeting macro-prudential tools. The Project will comparatively assess the resilience of European Banks to losses on common exposures pre- and post- QE, as the structure of overlapping networks is expected to change after the QE. The FINREALNET project is a perfect springboard for the Principal Investigator (PI) through the possibility to build durable research network, and acquire new skills which are complementary to her current expertise. Those new skills include research skills (theory and methodology), operational skills (algorithm writing), project management skills, language skills (German) and new data treatment skills (during the Secondment at the ECB). Moreover, working papers, presentations and recommendations for the regulator will improve the PI\u2019s visibility as a young researcher and contribute to her research career. FINREALNET also builds a solid foundation for future collaborations. Finally, FINREALNET by its training and research program aims at promoting women\u2019s integration in the domain of Economic research where a traditional gender gap persists.", "To": ["2018-05-31, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["704936"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["The Role of Circulating Monocytes in the Development of Brain Metastases"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["Brain Metastases"], "Technology_Description": "Brain metastases, particularly from breast cancer, are a significant clinical problem. About one fifth of breast", "To": ["2018-02-10, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-05-01"], "Project_ID": ["654985"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["ATHENS UNIVERSITY OF ECONOMICS AND BUSINESS - RESEARCH CENTER"], "EU_Contribution": ["EUR 82 326,60"], "Project_Title": ["Biomedical Information Synthesis with Deep Natural Language Inference"], "Total_Cost": ["EUR 82 326,60"], "Country": ["Greece"], "Project_ACR": ["DNLIBiomed"], "Technology_Description": "Deep neural networks (DNNs) have become a critical tool in natural language processing (NLP) for a wide variety of language technologies, from syntax to semantics to pragmatics. In particular, in the field of natural language inference (NLI), DNNs have become the de-facto model, providing significantly better results than previous paradigms. Their power lies in their ability to embed complex language ambiguities in high dimensional spaces coupled with non-linear compositional transformations learned to directly optimize task-specific objective functions. We propose to adapt Deep NLI techniques to the biomedical domain, specifically investigating question answering, information extraction and synthesis. The biomedical domain presents many key challenges and a critical impact that standard NLI challenges do not posses. First, while standard NLI data sets requires a system to model basic world knowledge (e.g., that \u2018soccer\u2019 is a \u2018sport\u2019), they do not presume a rich domain knowledge encoded in various and often heterogeneous resources such as scientific articles, textbooks and structured databases. Second, while standard NLI data sets presume that the answer/inference is encoded in a single utterance, the ability to reason and extract information from biomedical domains often requires information synthesis from multiple utterances, paragraphs, and even documents. Finally, whereas standard NLI is a broad challenge aimed at testing whether computers can make general inferences in language, biomedical texts are a grounded and impactful domain where progress in automated reasoning will directly impact the efficacy of researchers, physicians, publishers and policy makers.", "To": ["2018-09-30, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Greece"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["751722"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["LEUPHANA UNIVERSITAT LUNEBURG"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Social and ecological networks supporting biodiversity and food security"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["SENet"], "Technology_Description": "Halting biodiversity decline and ensuring food security are urgent and interconnected challenges. I will study how social and ecological structures in interaction generate tradeoffs and synergies between food security and biodiversity conservation. SENet has two aims: A) to identify ecological and socioeconomic structures that benefit or harm food security and biodiversity conservation in a rural, poor study landscape, and B) to develop an integrated network model capable of predicting such effects in similar settings worldwide. Globally, SENet will be the first research to apply (graph-theoretic) network analysis to understand synergies and tradeoffs in the food security\u2013biodiversity nexus. I will develop the integrated model using data from a landscape in Ethiopia, where agricultural expansion and human-wildlife conflicts are driving deforestation. SENet differs from existing approaches that concentrate on increasing agricultural output and overlook that social and ecological outcomes are interdependent and cannot be understood separately. In contrast, my method focuses on the food security of rural villages and on the factors that prompt farmers to clear or to plant forest, to change crops, to migrate elsewhere, etc., i.e., on farmers' decisions that affect both food security and biodiversity. In this context, I will use systematic network analysis to show how farmers are connected through food trade, knowledge exchange and other socioeconomic processes, but also how their crop fields are linked to forests and human\u2013wildlife conflicts. The implementation of SENet will draw on my skills in network analysis and the host\u2019s research excellence on the biodiversity of agricultural landscapes, including their ongoing fieldwork in my study area. This setup ensures a theoretical and empirical foundation for my network models, and a forum for communicating my results to non-academic actors in Ethiopia and Europe.", "To": ["2018-01-14, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-01-15"], "Project_ID": ["661780"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITAET BERN", "UNIVERSITAET BERN"], "EU_Contribution": ["EUR 1 989 938"], "Project_Title": ["Perception of Plant Volatiles"], "Total_Cost": ["EUR 1 989 938"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["PERVOL"], "Technology_Description": "The capacity to produce and perceive organic chemicals is essential for most cellular organisms. Plant leaves that are attacked by insect herbivores for instance start releasing distinct blends of herbivore-induced plant volatiles, which in turn can be perceived by non-attacked tissues. These tissues then respond more rapidly and more strongly to herbivore attack. One major question that constrains the current understanding of plant volatile communication is how plants perceive herbivore induced volatiles. Can plants smell danger by detecting certain volatiles with specific receptors? Or are other mechanisms at play? Answering these questions would push the boundaries of plant signaling research, as it would allow for the creation of perception impaired mutants to perform detailed analyses of the biological functions and potential agricultural benefits of plant volatile perception. ", "To": ["2022-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-03-01"], "Project_ID": ["714239"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["FREIE UNIVERSITAET BERLIN"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Nanoscale Effects within Biological Membranes caused by Radiation"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["NanoMembR"], "Technology_Description": "The NanoMembR project will elucidate key elements of membrane stability under the influence of UV radiation. The stability of biological membranes is of great importance for the structure, homeostasis and functioning of all living systems. Membrane molecules have also attracted, due to their robustness and longevity, strong interest from planetary and space scientists as potential biomarkers for life detection missions to other planets. Membrane damage, perturbation, instability and fragmentation upon UV exposure will be investigated on the nanoscale using cutting-edge infrared nanoscopy. Scattering-type scanning near-field microscopy (s-SNOM) combined with Fourier transform infrared (FTIR) spectroscopy allows to combine spatial information of nanometre resolution with chemical mapping. This novel technique will enable us to study subtle changes in the structural integrity of model membranes and monitor changes in the micro- and nano-domains. In addition, we will be able to correlate membrane stability and membrane composition by intercalating structural and functional modifiers such as sterols, hopanoids and pigments. Upon radiation in oxic environments, the lipid structure of a membrane is known to be altered by peroxidation chain reactions. Under anoxic conditions radiation induced changes in lipid alteration could vary significantly, with intriguing implications for the stability of membrane molecules under different environmental conditions than found on Earth. Understanding fragmentation patterns of membranes and identifying final break-down products will provide scientific support and a database for key biomarkers detectable in remote environments. Results from this work will feed directly into planned experiments on the International Space Station (ISS), which are scheduled on new nanosatellite-technology-based exposure platforms with in-situ infrared spectroscopic capabilities, monitoring membrane stability under the influence of solar and cosmic radiation.", "To": ["2019-05-15, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-16"], "Project_ID": ["706072"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITE DE BORDEAUX", "UNIVERSITE DE BORDEAUX"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Study on Environmental and GenomeWide predictors of early structural brain Alterations in Young students"], "Total_Cost": ["EUR 1 500 000"], "Country": ["France", "France"], "Project_ACR": ["SEGWAY"], "Technology_Description": "Mounting evidence suggests that early life factors have an important impact on the occurrence of late-life neurological diseases. From a public health perspective this is of particular relevance for dementia, the prevalence of which is increasing drastically, with no available preventive treatment, and epidemiological data suggesting that pathological processes may begin many years before clinical diagnosis. MRI-defined structural brain phenotypes are powerful intermediate markers for dementia, and can already show measurable alterations in young and middle-aged adults. These include global and regional brain volumes, gray matter volume and cortical thickness, and markers of white matter integrity. The SEGWAY project aims to: (i) explore the heritability and genetic determinants of structural brain phenotypes in young adults in their early twenties participating in the i-Share study, the largest ongoing student cohort; (ii) take a lifetime perspective by examining the shared genetic contribution to structural brain alterations in young adulthood (i-Share) and late-life, among participants of a large French population-based study (3C-Dijon); (iii) explore the interaction between genetic variants and vascular risk factors with established impact on structural brain phenotypes, in both age groups; (iv) examine the clinical significance of genetic risk variants for structural brain alterations by testing their association with cognitive performance in young and older adults. Replication and of our findings will be sought in the multigenerational Framingham Heart Study and other independent samples. Identifying common biological mechanisms underlying both early and late-life structural brain changes would provide important information on the mechanisms and timecourse of brain aging throughout a lifetime and could be of major importance for identifying of molecular drug targets and characterizing high risk populations most likely to benefit from early interventions.", "To": ["2020-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-12-01"], "Project_ID": ["640643"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["KOC UNIVERSITY", "KOC UNIVERSITY", "QUEEN MARY UNIVERSITY OF LONDON"], "EU_Contribution": ["EUR 1 089 432"], "Project_Title": ["Market Selection, Frictions, and the Information Content of Prices"], "Total_Cost": ["EUR 1 089 432"], "Country": ["Turkey", "Turkey", "United Kingdom"], "Project_ACR": ["INFORMATIVEPRICES"], "Technology_Description": "This project studies information aggregation in multiple-linked auction markets with large numbers of goods and bidders. Past work assumes bidders trade in a single, centralized, frictionless auction market. Instead, I study bidders with unit demand who decide to purchase one of many possible goods which are on auction in distinct markets. The goods traded in each market are identical, common-value objects and the price is determined by a uniform-price auction. Bidders receive imperfect signals about the state of the world and select to bid in one of the auction markets. The markets differ in institutional structure and therefore frictions. Market frictions result from imperfect competition, government interventions, informational frictions, and preference heterogeneity. All such frictions render the gains from trade uncertain.", "To": ["2021-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Turkey"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["681460"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["COLLEGE DE FRANCE", "COLLEGE DE FRANCE"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Wiring synaptic circuits with astroglial connexins: mechanisms, dynamics and impact for critical period plasticity"], "Total_Cost": ["EUR 2 000 000"], "Country": ["France", "France"], "Project_ACR": ["AstroWireSyn"], "Technology_Description": "Brain information processing is commonly thought to be a neuronal performance. However recent data point to a key role of astrocytes in brain development, activity and pathology. Indeed astrocytes are now viewed as crucial elements of the brain circuitry that control synapse formation, maturation, activity and elimination. How do astrocytes exert such control is matter of intense research, as they are now known to participate in critical developmental periods as well as in psychiatric disorders involving synapse alterations. Thus unraveling how astrocytes control synaptic circuit formation and maturation is crucial, not only for our understanding of brain development, but also for identifying novel therapeutic targets.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["683154"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["HELSINGIN YLIOPISTO"], "EU_Contribution": ["EUR 191 325,60"], "Project_Title": ["An analyzer for preterm EEG"], "Total_Cost": ["EUR 191 325,60"], "Country": ["Finland"], "Project_ACR": ["APE"], "Technology_Description": "Compromised early brain development leads to lifelong disabilities, which have a heavy impact on the child, families, as well as society as a whole. Advances in clinical care have led to an increasing number of babies surviving extreme prematurity. The global challenge is to avoid early brain injuries by optimizing neurological care during the early days of neonatal intensive care. This aim necessitates the use of constant, cot-side brain monitoring using the electroencephalograph (EEG), which faces formidable logistic challenges due to the need for large scale data analysis by EEG experts. The only imaginable solution for dealing with the vast amount of EEG information is to automate EEG analysis. This action proposes the development of an original, automated, cot-side Analyser for Preterm EEG (APE). This algorithm will be based on the combination of state of the art biomedical signal processing techniques and recent advances in basic developmental neuroscience. An accurate cot side EEG analyser has strong clinical potential for improving early brain care, leading to lifelong improvements in affected individuals as well as unprecedented opportunities to benchmark new brain interventions. The project will significantly develop the applicant\u2019s career by adding new domains of human neurophysiology and basic neuroscience, bio-signal analysis, as well as conduct of international research projects to his skillset. His secondment to a well-established Finnish SME in the field, MegaEMG, will provide insight into the development of medical devices, commercialization, and regularity environment. The technology developed in this project is translatable into medical devices, providing an opportunity to enhance Europe\u2019s status as a market leader in brain monitoring devices, as well as University of Helsinki\u2019s standing as a centre of excellence for neonatal neurophysiology.", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["656131"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["KATHOLIEKE UNIVERSITEIT LEUVEN", "KATHOLIEKE UNIVERSITEIT LEUVEN"], "EU_Contribution": ["EUR 149 875"], "Project_Title": ["Super-resolution genomic mapping for the microbiome"], "Total_Cost": ["EUR 149 875"], "Country": ["Belgium", "Belgium"], "Project_ACR": ["METAMAPPER"], "Technology_Description": "Animals and bacteria have been working together for about as long as they have co-existed, long before the advent of mankind. The bodies of our ancient ancestors offered protected, nutrient-rich habitats for bacteria. In return, animals could take an evolutionary short-cut to developing new capabilities by \u2018borrowing\u2019 bacterial genes. Indeed, when gut bacteria assist with the digestion of e.g. dietary fiber, the resulting metabolites will subsequently exert an influence on an intricate network of host molecular pathways. Gut microbiota, in addition to host genetics, can therefore constitute a major factor in the etiology of complex disorders, ranging from obesity, cardiovascular disease, autoimmune disease (multiple sclerosis, rheumatoid arthrosis), inflammation (inflammatory bowel disease, Crohn\u2019s) to neurological conditions.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["768826"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["COLLEGE DE FRANCE", "COLLEGE DE FRANCE"], "EU_Contribution": ["EUR 1 997 497,50"], "Project_Title": ["Josephson Junction Spectroscopy of Mesoscopic Systems"], "Total_Cost": ["EUR 1 997 497,50"], "Country": ["France", "France"], "Project_ACR": ["JSPEC"], "Technology_Description": "Spectroscopy is a powerful tool to probe matter. By measuring the spectrum of elementary excitations, one reveals the symmetries and interactions inherent in a physical system. Mesoscopic devices, which preserve quantum coherence over lengths larger than the atomic scale, offer a unique possibility to both engineer and investigate excitations at the single quanta level. Unfortunately, conventional spectroscopy techniques are inadequate for coupling radiation to mesoscopic systems and detecting their small absorption signals. I propose an on-chip, Josephson-junction based spectrometer which surpasses state-of-the-art instruments and is ideally suited for probing elementary excitations in mesoscopic systems. It has an original design providing uniform wideband coupling from 2-2000 GHz, low background noise, high sensitivity, and narrow linewidth.", "To": ["2020-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-04-01"], "Project_ID": ["636744"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM", "FUNDACIO INSTITUT DE CIENCIES FOTONIQUES", "POLITECNICO DI MILANO", "UNIVERSITY COLLEGE LONDON", "INSTYTUT BIOCYBERNETYKI I INZYNIERII BIOMEDYCZNEJ PAN", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "PHYSIKALISCH-TECHNISCHE BUNDESANSTALT", "UNIVERSITY HOSPITAL BIRMINGHAM NHS FOUNDATION TRUST", "FUNDACIO HOSPITAL UNIVERSITARI VALL D'HEBRON - INSTITUT DE RECERCA", "PICOQUANT INNOVATIONS GMBH", "HEMOPHOTONICS SL"], "EU_Contribution": ["EUR 3 835 764,36"], "Project_Title": ["Brain injury and trauma monitoring using advanced photonics"], "Total_Cost": ["EUR 3 835 764,36"], "Country": ["United Kingdom", "Spain", "Italy", "United Kingdom", "Poland", "France", "Germany", "United Kingdom", "Spain", "Germany", "Spain"], "Project_ACR": ["BitMap"], "Technology_Description": "Our vision is to develop a suite of standardised non-invasive devices that will provide essential information about brain health in neurocritical care and neuromonitoring, with a particular emphasis on 1. traumatic brain injury: the \u201csilent epidemic of the third millennium\u201d and 2. hypoxia in newborn children. Survivors present permanent neurological conditions that have a profound impact on the quality of life of individuals and their families, and hence a large socio-economic impact. The key factors influencing these conditions and their treatment are the avoidance of brain hypoxia and metabolic disturbances and this is driving the transfer of new neuromonitoring systems to the bedside where they are being shown to have a transformative effect on patient care.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Other", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-01-01"], "Project_ID": ["675332"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["INSTITUT CURIE", "INSTITUT CURIE"], "EU_Contribution": ["EUR 2 312 500"], "Project_Title": ["Exploring mechanisms of gene repression and escape during X-chromosome inactivation"], "Total_Cost": ["EUR 2 312 500"], "Country": ["France", "France"], "Project_ACR": ["XPRESS"], "Technology_Description": "During mammalian development, precise gene expression patterns have to be established and then maintained, or reversed, in different cellular and tissue contexts. A striking example of such developmentally regulated gene control is X-chromosome inactivation (XCI), whereby one of the two X chromosomes in females is silenced during embryogenesis. XCI is initiated by the non-coding Xist RNA, which coats the chromosome in cis, triggering gene repression, chromatin changes and chromosomal reorganisation. Although Xist\u2019s regulation has been investigated intensively, less is known about the actual mechanisms underlying the process of chromosome-wide gene silencing that it induces. Indeed, X-linked loci show very different kinetics of repression during development, implying regional and/or locus specific diversity. Furthermore, some genes avoid or escape XCI altogether, either constitutively or in a tissue or stage-specific fashion, but the molecular basis for this is unclear. Here we propose to dissect the mechanisms underlying gene regulation during XCI. We will investigate the roles of recently identified Xist partners in gene silencing and perform genetic screens to identify new factors involved in silencing and escape from XCI. Transcription, chromatin status and chromosome conformation during XCI will be investigated in an allelic-specific manner during precise developmental time windows to pinpoint the critical changes accompanying silencing and escape. We will use genetic engineering to alter genomic and epigenomic landscapes of selected loci and target candidate trans-acting factors to their putative regulatory elements. Finally, we will develop tools to explore gene expression during XCI using live cell imaging of embryogenesis. Using this innovative set of approaches, we hope to define both general principles underlying gene silencing and escape in XCI, as well as locus-specific features that could serve as new paradigms for research in developmental epigenetics.", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2015-11-01"], "Project_ID": ["671027"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["COLLEGE DE FRANCE", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Spinor Bose Gases in 1D: Equilibrium properties, Dynamics, and Spin-orbit coupling"], "Total_Cost": ["EUR 185 076"], "Country": ["France", "France"], "Project_ACR": ["Spin1D"], "Technology_Description": "The properties of materials are determined by the order in their most fundamental constituents, generally appearing at sufficiently low temperatures after a phase transition. This generic picture encompasses phenomena as diverse as: the ordering of atoms into perfectly periodic crystals, into superfluid phases for liquid Helium or dilute atomic gases, or even cosmological phenomena. In the case of magnetic materials, usually described in terms of localized spins on lattice, ordering refers to the spatial organization of spins. Examples of such organization are the ferromagnetic and anti-ferromagnetic phases in electronic (spin-1/2) systems: the former is characterized by the parallel alignment of adjacent electron spins in a lattice, while the latter exhibits an antiparallel arrangement of the spins. Spin-exchange interactions are responsible for the emergence of such magnetic quantum phases. Magnetic systems are of the utmost importance for fundamental and applied reasons. A general understanding the nature of magnetic quantum phases of matter requires the study of magnetic systems beyond spin-1/2, where more magnetic phases are possible. ", "To": ["2018-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2016-04-01"], "Project_ID": ["701894"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["An induced pluripotent stem cell-based neuronal model of Spinocerebellar ataxia"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["iPSCAtaxia"], "Technology_Description": "The spinocerebellar ataxias (SCAs) are a diverse group of neurological disorders defined by a loss of motor coordination. No effective treatments exist, and there is thus a pressing need for suitable models in which to study disease progression and to screen potential therapies. Induced pluripotent stem cells (iPSCs), which are capable of differentiation into any cell type of the body, offer the opportunity to study neurodegeneration in vitro. The proposed study aims to be the first in Europe to establish an iPSC-derived model of cerebellar disease, focusing on two genetic subtypes of SCA - SCA14 and 41. Increasing evidence points towards common pathological pathways shared across multiple SCA subtypes, which could provide novel therapeutic targets. There is also evidence to suggest that abnormalities in Purkinje cell development may contribute to the pathogenesis of the SCAs. This model will thus be used to elucidate the molecular mechanisms underlying common SCA-causing disease pathways, and to unravel the neurodevelopmental aspects of these diseases, in order to develop early-intervention therapies. Preliminary results indicate successful differentiation of iPSCs into cerebellar progenitor cells, using a protocol I have optimised. Following terminal differentiation, these cells will be investigated for common disease phenotypes and developmental defects, using a combination of transcriptomic, biochemical, and electrophysiological methods. Results will be validated by comparison with post-mortem brain samples and ataxic mouse models. By adapting this differentiation strategy to a format amenable to high-throughput screening, a pipeline will be established for the identification of novel therapeutic compounds. This groundbreaking study will enable the investigation of mechanisms which render the cells of the cerebellum particularly sensitive to degeneration, as well as providing a platform for pre-clinical screening of therapeutics for neurodegenerative conditions.", "To": ["2018-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-07-01"], "Project_ID": ["699978"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["COLLEGE DE FRANCE", "COLLEGE DE FRANCE"], "EU_Contribution": ["EUR 1 959 283"], "Project_Title": ["Saadian Intellectual and Cultural Life"], "Total_Cost": ["EUR 1 959 283"], "Country": ["France", "France"], "Project_ACR": ["SICLE"], "Technology_Description": "The aim of the interdisciplinary investigation project SICLE is to investigate in a completely new way the intellectual and cultural history of the Saadian period in Morocco (1554-1660), using primarily the Saadian sultans\u2019 library, exceptionally preserved as a \u2018time capsule\u2019 in the El Escorial monastery following king Felipe III\u2019s decision to include it in his own library. The period is a time of direct involvement of Morocco in international politics and exchanges, both in their East-West (with the Ottoman empire) and North-South (with Europe) dimensions, without forgetting Timbuktu and the Songhay empire conquered by Ahmad al-Mansur, the most brilliant ruler of the dynasty. The manuscripts kept in El Escorial mirror the interests and the tastes of the Saadian rulers and of the elite at large. The paratextual information they contain (but ignored by the catalogues) like the various notes, the colophons, the illuminations or the bindings will be systematically collected and analyzed in a trans-disciplinary approach which can be defined as an \u2018archaeology of the book\u2019, combining codicology, philology, archaeometry, anthropology and art history. The same approach will be applied to the books of the \u2018ordinary people\u2019 from Saadian times preserved in Moroccan collections. SICLE goals are to offer: a) a history of the Saadian sultans\u2019 library and an analysis of their interests; b) a cultural and intellectual history of Morocco during the 16th century, with groundbreaking studies on the history of the book, on its economy and on education; c) an evaluation of the relationship with the \u2018outside\u2019 (Christian Europe, the Ottoman empire and sub-Saharan Africa) and the possible influence it had on Saadian intellectual production. Special attention will be paid to the Jewish and Morisco communities in their role of culture brokers.", "To": ["2021-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-02-01"], "Project_ID": ["670628"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["WISSENSCHAFTSZENTRUM BERLIN FUR SOZIALFORSCHUNG GGMBH"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["International Authority and Intellectual Domination: External Donors and Local Organizations in Latin American Social Sciences (1945-1973)."], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["PHILANTHROPIC RULE"], "Technology_Description": "Scholars interested in Global Governance and international authority favour a broadly Weberian idea of legitimacy as the explanation for the stability and effectiveness of international authority. However, I expand here the focus of analysis in order to include additional concepts like \u201ccommonality of interests\u201d and \u201cmeans of domination\u201d, which are crucial for Weber, but absent from the IR literature on international authority. Among the means of domination, knowledge is of particular importance because it distinguishes the rational from the other types of domination, which explains why knowledge, experts, and diplomats have become an increasingly important topic for IR scholars interested in organizations and in authority. The potential consequences of international authority at local level, like resistance and protection, also receive their due consideration. To put it in a nutshell, what this project pretends is to offer a better account of how donor organizations transfer knowledge, money, goods, salaries to local organizations like universities and research centres, purportedly with the intention of making possible for recipients to pursue their educative policies goals and policies. In reality, I submit, these are \u201cmeans of domination\u201d that foundations and IOs award local actors so that they operate teaching programs and research projects chosen by the patrons or, in other words, in order to move local actors to collaborate in realizing the goals of donors. In empirical terms, the question is to what extent international organizations \u2013 UNESCO, ONU \u2013 and transnational ones \u2013 philanthropic foundations like Rockefeller and Ford \u2013 succeed or failed in their efforts to wield influence on academic organizations, more specifically on teaching and research in the social sciences, in Latin America during the post-war years (1945-1973).", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations"], "From": ["2017-07-01"], "Project_ID": ["702562"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["COLLEGE DE FRANCE", "COLLEGE DE FRANCE"], "EU_Contribution": ["EUR 1 483 143,75"], "Project_Title": ["Morphogenesis and Molecular Regulation of Colour Patterning in Birds"], "Total_Cost": ["EUR 1 483 143,75"], "Country": ["France", "France"], "Project_ACR": ["COLOUR PATTERN"], "Technology_Description": "Animals display a tremendous diversity of patterns \u2012from the colourful designs that adorn their body to repeated segmented appendages. Natural patterns result from the formation of discrete domains within developing tissues through the integration of positional cues by cells that consequently adopt specific fates and produce spatial heterogeneity. How can such developmental processes underlie the apparent complexity and diversity of natural patterns? We propose to address this long-standing question with an innovative experimental design: we will make use of natural variation as a powerful tool to facilitate the identification of patterning molecules and morphogenetic events. We will study colour pattern, a crucial adaptive trait that varies extensively in nature, from large colour domains to periodic designs. In amniotes, colour pattern is formed by spatial differences in the distribution of pigment cells and integumentary appendages. While the pigmentation system has been well characterized, the mechanisms governing the formation of compartments in the skin of wild animals have remained unclear, largely because laboratory models do not display ecologically-relevant colour patterns. We will use a combination of forward genetics, developmental biology, modelling, and imaging to study natural variation in the large colour domains of Estrildid finches and the periodic stripes of Galliform birds. For both phenotypes, we will characterize the organization of the embryonic skin and the mode of patterning (i.e., instructional patterning via external cues vs locally-occurring self-organization) underlying their formation, and identify the molecular factors and developmental processes contributing to their variation. Results from these studies will elucidate the biochemical events and tissue rearrangements orchestrating colour patterning in development and shed light on how these processes shape natural variation in this trait\u2012 and more generally, in natural patterns.", "To": ["2020-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-05-01"], "Project_ID": ["639060"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["COLLEGE DE FRANCE"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Topological superfluidity in ultracold gas of Dysprosium atoms"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["Topological superfluidity"], "Technology_Description": "In the last decade experimental and theoretical studies in condensed matter demonstrated that materials with strong spin-orbit coupling can host a new state of matter for the electron gas - a topological insulator. More recently the concept of topological matter was generalized theoretically to superconducting systems with strong spin-orbit coupling. The topological character manifests itself in the presence of quantum states bound to edges or defects that exhibit exotic physical properties. In topological superconductors, edge states are described as Majorana fermions. These exotic particles - originally predicted in high-energy physics - are non-abelian anyons: their quantum statistics is neither bosonic nor fermionic. Observing Majorana fermions would be the first demonstration of such exotic particles. The field of ultracold atoms seems well suited for the realization of superfluid systems with strong spin-orbit coupling. As shown in recent experimental works, manipulating manipulating atomic internal states with lasers can mimick spin-orbit couplings of strong amplitude. We have constructed at College de france a new experimental setup producing ultracold Dysprosium atomic gases. This atomic species exhibits narrow electronic transitions that should allow one to create such a spin-orbit coupling without substantial heating, which is the main requisite for creating a superfluid state. Combining spin-orbit coupling and strong interactions should lead to the formation of a topological superfluid. We will investigate the structure of quasi-particle excitations of this superfluid, which should exhibit edge modes described as Majorana fermions.", "To": ["2017-04-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-05-01"], "Project_ID": ["661433"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["STICHTING VUMC", "STICHTING VUMC", "STICHTING VU"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["GlioDx - Blood platelet-based monitoring and treatment optimisation for glioblastoma patients"], "Total_Cost": ["EUR 150 000"], "Country": ["Netherlands", "Netherlands", "Netherlands"], "Project_ACR": ["GlioDx"], "Technology_Description": "Glioblastoma (GBM) is a devastating primary brain cancer which affects about 230.000 people annually. The choice for treatment depends on the subtype of GBM. An accurate detection of tumour subtype is therefore essential for a personalised targeted treatment. Diagnosis, classification and treatment monitoring occurs currently by radiology and repeated invasive biopsies. There is a need for non-invasive, actionable biomarkers for early-stage diagnosis and disease monitoring.", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2015 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["713727"], "Call_for_Proposal": ["ERC-2015-PoC"]}, -{"Partners": ["ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA"], "EU_Contribution": ["EUR 159 034,56"], "Project_Title": ["NEURODIVERSITY BETWEEN LAW AND SCIENCE"], "Total_Cost": ["EUR 159 034,56"], "Country": ["Italy"], "Project_ACR": ["NEDBELS"], "Technology_Description": "The aim of the research proposal \u201cNeurodiversity between Law and Science\u201d (NEDBELS) is to inquire into the legal impacts and socio-political implications of the concept of neurodiversity. This term pertains to individuals diagnosed with neurodevelopmental disorders such as Asperger\u2019s Syndrome and Autism and hypothesizes the emergence of a new category of difference in the human population. NEDBELS explores how this concept challenges the constitutional principle of equality, as well as how it fosters the need to accommodate new principles in criminal and civil law. This proposal has risen from a need for heightened communication between law and science. Scientific theories, concepts and methods widely permeate law and adjudication, and legal and ethical frameworks intimately drive applied sciences, as in education and health care systems. Therefore, one might reasonably expect that these two worlds would cooperate on a regular basis. However, lawyers, scientists and health care professionals operate largely insulated from one another in research, formal training and daily practice. This divergence prevents vulnerable minorities, such as people with neurodevelopmental disorders, from reaping the full socio-political potential of scientific advancements. NEDBELS\u2019s goal is to increase communication between law and neurosciences through interdisciplinary research methodologies and scientific training-through-research as well as by enhancing the synergy among legal experts, policy makers and scientists in the field of neurodiversity", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["656988"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITAETSKLINIKUM AACHEN", "UNIVERSITAETSKLINIKUM AACHEN"], "EU_Contribution": ["EUR 145 312"], "Project_Title": ["Companion Nanodiagnostics for Quantifying EPR and Stratifying Patients to Targeted Nanotherapies"], "Total_Cost": ["EUR 145 312"], "Country": ["Germany", "Germany"], "Project_ACR": ["CONQUEST"], "Technology_Description": "CONQUEST aims to commercialise a first-of-its-kind platform technology for imaging a biological effect \u2013 i.e. the EPR effect \u2013 that is predictive for a cancer patient's response to tumor-targeted nanomedicine (NM) therapy. CONQUEST thereby addresses a key issue in the (nano)pharmaceutical industry; as currently large proportions of cancer patients do not respond to NM, while others show major improvements in terms of response rates, survival times and quality of life. This trend impairs the outcome of clinical studies and results in many patients receiving treatments that are not effective to them. It would therefore be highly desirable to stratify responders from non-responders prior to study entry or treatment. CONQUEST stands at the basis of introducing a solution to this problem in the pharmaceutical industry. ", "To": ["2017-06-30, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2015 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["680882"], "Call_for_Proposal": ["ERC-2015-PoC"]}, -{"Partners": ["CONSIGLIO NAZIONALE DELLE RICERCHE", "MEDITERRANEAN AGRONOMIC INSTITUTE OF CHANIA", "INSTITUT NATIONAL D'ETUDES SUPERIEURES AGRONOMIQUES DE MONTPELLIER", "UNIVERSITA DEGLI STUDI DI PERUGIA", "AGRICULTURAL UNIVERSITY OF ATHENS", "INSTITUTO ANDALUZ DE INVESTIGACIONY FORMACION AGRARIA PESQUERA ALIMENTARIA Y DE LA PRODUCCION ECOLOGICA", "CONFEDERAZIONE ITALIANA AGRICOLTORI REGIONALE UMBRIA", "SYNDESMOS BIOMHCHANON TYPOPOIHTON EXAGOGON ELAIOLADOY", "OPTIMUM QUALITY SL"], "EU_Contribution": ["EUR 1 296 000"], "Project_Title": ["Bioresources For Oliviculture"], "Total_Cost": ["EUR 1 296 000"], "Country": ["Italy", "Greece", "France", "Italy", "Greece", "Spain", "Italy", "Greece", "Spain"], "Project_ACR": ["BeFOre"], "Technology_Description": "The project aims at establishing a multi-lateral network of research and innovation staff active in olive germplasm access, conservation, evaluation and exploitation, strengthening research capacities through the exchange of knowledge and expertise on a shared research programme focused on developing integrated common protocols to phenotype and characterize plants at molecular, morphological and physiological level, and evaluating the olive oil quality related to varieties. The scientific results of the project will contribute at improving the potential of the olive germplasm collections, repositories and banks as main sources of variability and of the evaluation tools to be used to increase oliviculture sustainability. Particular attention will be paid to issues concerned to international intellectual property rights for conserving, exchanging and using the olive genetic resources. Another aim is to create a long lasting network among partners also promoting new common projects in the frame of Horizon2020 and other international funding sources. The joint exchange programme will involve 9 beneficiaries and 6 partners belonging to AC and NAC sectors and will be performed through a series of short and long term staff exchanges and workshops among European (Italy, Spain, Greece and France) and third countries (Morocco, Lebanon, Jordan, Argentina, Chile and Mexico). The International Olive Council (IOC), represented by IOC Executive Director, Jean-Louis Barjol, expressed its strong support to \u201cBeFOre\u201d planning to play an important role in dissemination activities. Experienced and early stage researchers, technicians and managers, are expected to be exchanged between EU and TC to ensure a good scientific transfer of knowledge and training. Enhancement of careers for the staff involved is expected. The project coordination and management will be ensured by the contribution of a well established coordination group and a Steering Committee.", "To": ["2019-01-31, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Other", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-02-01"], "Project_ID": ["645595"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["TECHNOLOGIKO PANEPISTIMIO KYPROU", "UNIVERSITA DEGLI STUDI ROMA TRE", "ARISTOTELIO PANEPISTIMIO THESSALONIKIS", "UNIVERSITY COLLEGE LONDON", "TELEFONICA INVESTIGACION Y DESARROLLO SA", "SIGNALGENERIX LTD", "INNOVEITORS (INNOVATORS) EFARMOGES YPSILIS TECHNOLOGIAS AE", "CY.R.I.C CYPRUS RESEARCH AND INNOVATION CENTER LTD", "LSTECH LTD"], "EU_Contribution": ["EUR 2 160 000"], "Project_Title": ["EnhaNcing seCurity And privacy in the Social wEb: a user centered approach for the protection of minors"], "Total_Cost": ["EUR 2 160 000"], "Country": ["Cyprus", "Italy", "Greece", "United Kingdom", "Spain", "Cyprus", "Greece", "Cyprus", "United Kingdom"], "Project_ACR": ["ENCASE"], "Technology_Description": "ENCASE will leverage the latest advances in usable security and privacy to design and implement a browser-based architecture for the protection of minors from malicious actors in online social networks. The ENCASE user-centric architecture will consist of three distinct services, which can be combined to form an effective protective net against cyberbullying and sexually abusive acts: a) a browser add-on with its corresponding scalable back-end software stack that collects the users\u2019 online actions to unveil incidents of aggressive or distressed behavior; b) a browser add-on with its associated scalable software stack that analyses social web data to detect fraudulent and fake activity and alert the user; and c) a browser add-on that detects when a user is about to share sensitive content (e.g., photos or address information) with an inappropriate audience and warns the user or his parents of the imminent privacy threat. The third add-on has usable controls that enable users to protect their content by suggesting suitable access lists, by watermarking, and by securing the content via cryptography or steganography. The three browser add-ons and the back-end social web data analytics software stack will be assessed with user studies and piloting activities and will be released to the public. The foundation of the research and innovation activities will be a diligently planned inter-sectorial and interdisciplinary secondment program for Experienced and Early Stage Researchers that fosters knowledge exchange. The academic partners will contribute know-how on user experience assessment, large scale data processing, machine learning and data-mining algorithm design, and content confidentiality techniques. The industrial partners will primarily offer expertise in production-grade software development, access to real-world online social network data, and access to numerous end-users through widely deployed products.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Cyprus"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-01-01"], "Project_ID": ["691025"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM"], "EU_Contribution": ["EUR 160 800"], "Project_Title": ["Pulsed plasma technology for 2D materials integration"], "Total_Cost": ["EUR 160 800"], "Country": ["Belgium"], "Project_ACR": ["PULSE2D"], "Technology_Description": "Atomically thin layers of transition metal dichalcogenides (TMD) are gaining increasing attention as new materials for future Beyond-CMOS electronics. Recently, a great progress has been made in deposition of high quality layers of TMDs paving the way towards wafer scale device manufacturing. However, many fundamental and technological challenges still have to be addressed. Precise tuning of the number of layers, doping, surface functionalization and selective low damage etching of TMDs are among the most critical technological steps. Plasma processing is an enabling technology used for doping, etching and deposition of ultrathin layers in microelectronics industry. However, the application of plasmas for integration of 2D materials remains marginal and poorly controlled. The major challenge for plasma treatment of atomically thin materials is the need for unprecedented control of fluxes and energies of plasma species at the substrate. Pulsed plasma technology holds promise of reaching conditions required for low damage processing of 2D materials with a single atomic layer precision. The ambition of PULSE2D is to develop highly controlled pulsed-plasma technology for integration of TMDs in nano-electronic devices on a wafer-scale. A fundamental study of the mechanisms of interaction between pulsed plasmas and atomically thin TMD materials will be performed. Defect production, adsorption and etching processes will be quantified as a function of plasma parameters. This information will be used to perform atomic layer etching, functionalization and defect healing of TMDs using pulsed plasmas. The research and training activities will enhance technical skills of the candidate in the emerging area of plasma processing of 2D materials, industry-relevant nano-fabrication and measurement of TMDs transport characteristics. High fundamental and technological interest and timeliness of this subject will provide a powerful thrust for the future research career of the candidate.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Belgium"], "Activity": ["Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["752164"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["AKZO NOBEL CHEMICALS BV"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["Better tools for combating insect borne diseases by understanding influences on the fate of common pesticides in paint formulations"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["ChiPyrNMR"], "Technology_Description": "Malaria, Zika virus, dengue fever and yellow fever are mosquito transmitted diseases for which a vaccines either do not exists or are not widely available. Prevention control is the main way to reduce their spread, and the use of insecticides constitutes one of the key measures recommended by World Health Organisation. New innovative methods of bringing the insects into contact with the insecticides include the development of insecticidal paint with the advantage of safer application, targeted dosing and significantly reduced risk of collateral damage to humans and the environment. This project will address some of the challenges in developing these solutions. ", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-SE - Society and Enterprise panel"], "Coordinated_in": ["Netherlands"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-09-01"], "Project_ID": ["749083"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS", "AUDYSSEY LABORATORIES INC"], "EU_Contribution": ["EUR 254 457"], "Project_Title": ["CAPTURING AND REPRODUCTION OF CROWDED ACOUSTIC ENVIRONMENTS FOR IMMERSIVE APPLICATIONS"], "Total_Cost": ["EUR 254 457"], "Country": ["Greece", "United States"], "Project_ACR": ["CROWDMERSE"], "Technology_Description": "CROWDMERSE enables real-time capture, processing, and reproduction of an immersive audio experience to the user of any event of interest, focusing on \u201ccrowded\u201d acoustic events. Acoustic scenes with large audiences, such as sports events or music concerts, present significant challenges for immersive reproduction which have not been so far adequately considered in the signal processing community. Technological breakthrough in sports events broadcasting has a strong potential impact on media providers, and consequently on the European and global economy. The challenges of capturing and reproducing crowded acoustic events include the need to spatially capture and reproduce numerous sound sources, such as the applause and yells of the spectators, in addition to the \u201cmain\u201d sounds of the event. Concerns regarding the privacy of the spectators must not be overlooked: the conversations of the audience members sitting near the microphone sensors must be eliminated. In order to spatially sample large venues, the acoustic sensors should be low-cost, small-sized, and support wireless operation. The developed algorithms should respect the limited sensor resources, while operating in real-time to enable commercial applications. Our final objective is to enable real-time delivery of crowded acoustic events so that the designed platform can be integrated with today\u2019s High-Definition TV programs. CROWDMERSE focuses on sound capturing using multiple closely placed microphones forming a microphone array. The audio content is rendered through a home entertainment system equipped with multiple loudspeakers, accompanying the content of a typical HDTV broadcast. Addressing the scientific challenges and proposing a solution which can be integrated with current broadcasting principles is guaranteed given the previous involvement of the experienced researcher in sports broadcasting projects. The proposed methods are expected to have impact in the general area of immersive sound environments.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Greece"], "Activity": ["Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-10-01"], "Project_ID": ["745677"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF STRATHCLYDE", "UNIVERSITY OF GLASGOW", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSITA DEGLI STUDI DI MILANO", "WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER", "EBERHARD KARLS UNIVERSITAET TUEBINGEN", "UNIVERSITAT DES SAARLANDES", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "UNIVERSITAET INNSBRUCK", "M-SQUARED LASERS LIMITED", "TOPTICA PHOTONICS AG", "HOLOEYE PHOTONICS AG"], "EU_Contribution": ["EUR 3 893 423,76"], "Project_Title": ["Collective effects and optomechanics in ultra-cold matter"], "Total_Cost": ["EUR 3 893 423,76"], "Country": ["United Kingdom", "United Kingdom", "France", "Italy", "Germany", "Germany", "Germany", "Switzerland", "Austria", "United Kingdom", "Germany", "Germany"], "Project_ACR": ["ColOpt"], "Technology_Description": "The network \u201cCollective effects and optomechanics in ultra-cold matter\u201d (ColOpt) will train early-stage researchers (ESR) in fundamental science and applications in the areas of cold atom and quantum physics, optical technologies and complexity science to promote European competiveness in emergent quantum technologies. It consists of nine academic nodes and three companies from six European countries, supported by two partners in Brazil and the USA, five further non-academic partners and one public-private partnership. ", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Corinna Hahn", "Tel.: +49 681 95 92 3362", "Fax: +49 681 95 92 3370", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["721465"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["ECOLE CENTRALE DE NANTES", "ECOLE CENTRALE DE NANTES"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Industrialization of software and libraries for crack propagation in material and structures using the Thick Level Set method"], "Total_Cost": ["EUR 150 000"], "Country": ["France", "France"], "Project_ACR": ["MATCRACK"], "Technology_Description": "The understanding and the reliable prediction of material degradation, crack initiation and propagation is of vital importance in engineering. It allows the evaluation of product lifecycle and the criticality of exceptional loads. Also, it enables maintenance optimization in a wide range of industries (automotive, aircraft, nuclear\u2026). Thanks to the ERC \u201cXLS\u201d grant, a new approach coined TLS (\u201cThick Level Set\u201d) was developed to simulate crack propagation from sane material to critical rupture. The main advantage of this approach is that it takes into account both crack initiation and crack propagation without mesh size or mesh orientation dependency. This combination is not currently available in the industry.", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["766820"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 148 375"], "Project_Title": ["Electrochemical Testing Platform for Advanced Energy Materials"], "Total_Cost": ["EUR 148 375"], "Country": ["France", "France"], "Project_ACR": ["EMPhAsIS"], "Technology_Description": "\"Throughout history, the Li-ion battery technology has relied on cationic redox reactions as the sole source of energy storage capacity. This is no longer true since 2013, where our group had demonstrated that Li-driven reversible formation of (O2)n peroxo-groups in new layered oxides led to extraordinary increases in energy storage capacity. To fully exploit this discovery we were granted in 2015 an advanced ERC grant entitled \"\"Anionic redox processes: A transformational approach for advanced energy materials (ARPEMA)\"\", the goal being to rationalize the fundamental science underpinning this new concept. This calls for new paradigms in characterization techniques to fully track among others the stability of these new compounds as well as the side reactions that they could generate at both electrodes during cycling together with their transport and kinetic properties. To address this critical need we developed a new design test system which enables for monitoring potential, current, temperature, pressure as well as the nature and composition of the released gases together with the impedance built-up at each electrode. Owing to the relative simplicity, high versatility and great reliability of such a new-patented multi-function testing device we anticipate its rapid implementation to various battery technologies. The goal of this project is to develop a proof of concept prototype and a small series production, as well as performing an extensive market analysis and budgeting suppliers, all for establishing an accurate business proposition. This information will be consolidated in a business plan and will be used in the creation of a company together with potential investors. We believe that this device will enable a rapid development of the next generation of high energy density batteries and consists in a global market commercial opportunity.\"", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-07-01"], "Project_ID": ["755456"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON", "UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 148 550"], "Project_Title": ["A neural network builder with remotely controlled parallel computing"], "Total_Cost": ["EUR 148 550"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["NEUROCLOUD"], "Technology_Description": "Neural network simulations have been a driving force behind our advances in the artificial intelligence filed, but also a key tool in our understanding of the human brain. However, exploring such networks usually engages substantial computational resources requiring specific programing skills and dedicated facilities. In our main project NETSIGNAL, we have developed computational environment ARACHNE aiming to facilitate high-end neural network exploration among scientific and industrial users. ARACHNE enables an investigator to construct and explore cellular networks of arbitrary biophysical and architectural complexity using a simple interface on a local computer or a mobile device. Through small-file exchange via the internet, the interface controls a pre-configured computational kernel installed on a remote computer cluster or cloud. Uniquely, ARACHNE can integrate traditional wired network connections with diffuse, volume-transmitted type of inter-cellular signalling, to reflect the emerging role of glia in brain processing. ARACHNE thus affords a flexible neural network design and incorporates latest advances in neuroscience while providing a portable console suitable for IT-untrained explorers. ARACHNE has passed a feasibility and novelty test by independent experts (Aleksin et al, PLoS Comp Biology 2017, in press), its test version is available on-line (https://github.com/LeonidSavtchenko/Arachne/). Our goal here is to determine market potential and the commercial viability of ARACHNE and its conceptual design, but also to establish industry-standard provisions for its commercial exploitation. We plan: (a) to upgrade ARACHNE technical specs, interface, support, etc. to the industry standard; (b) to assess the market and the competitors; (c) to determine IPR position and strategy, (d) to explore budgeting and further funding strategy, (e) to establish initial provisions for its distribution and/or licensing of ARACHNE.", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["767372"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["UNIVERSITE DE MONTPELLIER"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Venomics In Predator-prey Systems"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["VIPS"], "Technology_Description": "Marine invertebrates are a rich source of bioactive compounds, including complex venoms that are highly effective and specific, having evolved through million years of natural selection. Despite their potential for drug discovery, chemical diversity of animal venoms is largely uncharacterized. Recent venomics research led to important technological advances: it is time for an expansion to neglected organisms that could lead to the discovery of compounds with novel biological activities. The main goal of VIPS Project is to address the biochemical diversification of two previously untapped marine predator-prey systems involving an Anthozoan and a corallivorous snail, both producing toxic secretions. The Researcher will be integrated into the research environment of the Universit\u00e9 de Montpellier, where the integration of different research fields (including genomics, proteomics, molecular evolution, peptide synthesis, and electrophysiology) will be used to discover and functionally characterize new bioactive compounds, define their interactions, highlight their evolutionary role and, through secondment, valorise their applicative potential. Focusing on venomous predator-prey couples is an innovative approach that will facilitate the identification of biological activity and evolutionary role of venom components. Wide diffusion of the VIPS Project will be ensured through open access to publications and data, and a variety of communication activities for the lay public that will exploit the appeal of predator-prey systems to highlight the link between basic and applied research. The activities of VIPS Project perfectly complement the background of the Researcher, allowing the achievement of full control over all stages of venomics research, and the development of new transferable skills that will foster her career. VIPS goals are highly relevant to Horizon2020, including the discovery of more efficient and specific drugs and the development of marine biotechnologies.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["748902"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["TECHNISCHE UNIVERSITAT DARMSTADT", "TECHNISCHE UNIVERSITAT DARMSTADT"], "EU_Contribution": ["EUR 2 499 789"], "Project_Title": ["A Global History of Technology, 1850-2000"], "Total_Cost": ["EUR 2 499 789"], "Country": ["Germany", "Germany"], "Project_ACR": ["GLOBAL-HOT"], "Technology_Description": "What role did technology play in the age of colonization and globalization? The proposed project, A Global History of Technology, 1850-2000 (GLOBAL-HOT), explores this vital question. ", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["742631"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["TECHNISCHE UNIVERSITAET DRESDEN", "TECHNISCHE UNIVERSITAET DRESDEN"], "EU_Contribution": ["EUR 2 380 425"], "Project_Title": ["Designer recombinases for efficient and safe genome surgery"], "Total_Cost": ["EUR 2 380 425"], "Country": ["Germany", "Germany"], "Project_ACR": ["GENSURGE"], "Technology_Description": "Recent breakthroughs in the field of genome editing provide a genuine opportunity to establish innovative approaches to repair DNA mutations to replace, engineer or regenerate malfunctioning cells in vitro or in vivo. However, most of the recently developed technologies introduce double-strand DNA breaks at a target locus as the first step to gene correction. These breaks are subsequently repaired by one of the cell intrinsic DNA repair pathways, typically inducing an abundance of insertions and deletions (indels). Ideally, for many applications genome editing should, however, be efficient and specific, without the introduction of indels. Site-specific recombinases (SSRs) allow precise genome editing without triggering endogenous DNA repair pathways and possess the unique ability to fulfill both cleavage and immediate resealing of the processed DNA in vivo. However, customizing the DNA binding specificity of SSRs is not straightforward. With this project, we propose to solve this shortcoming. We have already demonstrated that by applying substrate-linked directed evolution, SSRs can be generated that specifically recognize therapeutic targets. The objective of this project is the development of a universal genome editing platform that allows flexible, efficient and safe gene corrections in cells of any origin without triggering cell intrinsic DNA repair. GenSurge aims to: i) sequence an unprecedented, comprehensive compendium of evolved SSRs to understand the directed molecular evolution process at nucleotide resolution; ii) integrate the knowledge obtained in i) to develop a unique SSR-based approach to correct genomic inversions; iii) develop a universal SSR-based strategy that allows flawless, precise and safe genome editing to correct any gene defect in human, animal or plant cells. The successful implementation of this project will deliver a comprehensive, safe and efficient platform from which genome surgery-based cure strategies can be initiated.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["742133"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE", "ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE"], "EU_Contribution": ["EUR 1 998 393,75"], "Project_Title": ["Inside the Self: from interoception to self- and other-awareness"], "Total_Cost": ["EUR 1 998 393,75"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["INtheSELF"], "Technology_Description": "Modern psychology has long focused on the importance of the body as the basis of the self. However, this focus concerned the exteroceptive body, that is, the body as perceived from the outside, as when we recognize ourselves in the mirror. This influential approach has neglected another important dimension of the body, namely the interoceptive body, that is, the body as perceived from within, as for example when one feels her racing heart. In psychology, research on interoception has focused mainly on its role in emotion. INtheSELF, however, goes beyond this approach, aiming instead to show how interoception and interoceptive awareness serve the unity and stability of the self, analogous to the role of interoception in maintaining physiological homeostasis. To test this hypothesis we go beyond the division between interoception and exteroception to consider their integration in self-awareness. INtheSELF will develop novel, pioneering methods for the study of causal relationships between interoceptive and exteroceptive awareness (WP1), allowing us to test how these two sources of information about the self interact to reflect the balance between stability and adaptation (WP2); how their inter-relation is built in parallel to the development of self-awareness in early childhood and adolescence (WP3); and the role that their interaction has for social relatedness (WP4). INtheSELF provides an alternative to existing psychological theories of the self insofar it goes beyond the apparent antagonism between the awareness of the self from the outside and from within, to consider their dynamic integration. In doing so, INtheSELF aims to elucidate for the first time how humans navigate the challenging balance between inside and out, in terms of both the individual\u2019s natural (interoception vs. exteroception) and social (self vs. others) embodiment in the world.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["724537"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON", "UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Neurocognitive mechanisms of inhibitory control training and transfer effects in children"], "Total_Cost": ["EUR 1 500 000"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["DEVBRAINTRAIN"], "Technology_Description": "Inhibitory control refers to the ability to control behavioural impulses and is critical for cognitive development. It has been traditionally thought of as a stable trait across the lifespan but recent insights from cognitive neuroscience show prolonged changes in brain regions that support inhibitory control indicating greater malleability than previously believed. Because childhood inhibitory control predicts well-being later in life this suggests exciting opportunities for enhancing inhibitory control. I build on highly promising pilot results and draw on a recent neurocognitive model of inhibitory control to test 1) if inhibitory control can be enhanced during childhood, 2) if this transfers onto other domains important for healthy psychological development such as prosocial- and patient decision-making and academic achievement and 3) which factors predict training success. Children aged 5 to 10 years will undergo 8 weeks of inhibitory control training, which is a critical duration for observing prolonged training effects and be compared to a group undergoing active sham-training of comparable stimuli and duration but without inhibition. I will assess training effects on the brain and look at transfer effects onto other domains such as other executive functions, prosocial- and patient decision-making and academic achievement, both immediately and 1 year after training. I expect training to 1) improve inhibitory control, 2) transfer onto performance on above-mentioned domains and 3) elicit neural changes indicating the effectiveness of training for re- and proactive control. I also expect that individual differences in inhibitory control ability and associated brain regions prior to training will predict training success. The proposed research has the potential to generate a new and ground-breaking framework on early malleability of inhibitory control with implications for interventions at the time point of greatest likely impact.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["715282"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["KUNGLIGA TEKNISKA HOEGSKOLAN", "KUNGLIGA TEKNISKA HOEGSKOLAN"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Distributed and Dynamic Graph Algorithms and Complexity"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["DisDyn"], "Technology_Description": "This project aims to (i) resolve challenging graph problems in distributed and dynamic settings, with a focus on connectivity problems (such as computing edge connectivity and distances), and (ii) on the way develop a systematic approach to attack problems in these settings, by thoroughly exploring relevant algorithmic and complexity-theoretic landscapes. Tasks include", "To": ["2022-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-02-01"], "Project_ID": ["715672"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["INSTITUT JOZEF STEFAN", "INSTITUT JOZEF STEFAN", "CENTER ODLICNOSTI NANOZNANOSTI IN NANOTEHNOLOGIJE - NANOCENTER, LJUBLJANA"], "EU_Contribution": ["EUR 149 452"], "Project_Title": ["Ultrafast charge density wave memory for quantum computing"], "Total_Cost": ["EUR 149 452"], "Country": ["Slovenia", "Slovenia", "Slovenia"], "Project_ACR": ["Umem4QC"], "Technology_Description": "The goal of the PoC is to take a newly discovered phenomenon in quantum electronic materials into a potentially disruptive memory technology offering unprecedented high speed, low energy consumption combined with low temperature operation. With the PoC grant we aim to establish: ", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Slovenia"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations"], "From": ["2017-07-01"], "Project_ID": ["767176"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 276 107,40"], "Project_Title": ["The Nexus: an experimental system to study marine larval dispersal"], "Total_Cost": ["EUR 276 107,40"], "Country": ["United Kingdom"], "Project_ACR": ["Nexus"], "Technology_Description": "Dispersal is a fundamental trait for the ecological and evolutionary dynamics of any given species. In marine systems, the primary means of connectivity among fragmented habitats is pelagic larval dispersal (LD). Due to the inherent difficulty of tracking minute larvae in the ocean, we are still lacking critical insights into the internal and external causes and consequences of LD. Here, we propose the development of an experimental infrastructure, the Nexus, composed of 25 interconnected larval rearing/settlement tanks, designed to study larval movements as a model of dispersal. We aim to use the Nexus framework to investigate central questions in LD theory that, up to this point, have been difficult to assess: (1) Do marine organisms exhibit condition-dependent dispersal strategies? (2) If so, how does the interaction of phenotype and environment affect dispersal behaviours (context-dependence)? (3) How will climate change affect condition- and context-dependent dispersal in offspring via parental effects? These are timely issues to address, as a better understanding of the underlying mechanisms regulating LD will help predict species\u2019 responses to rapid environmental change. The intended framework will facilitate the holistic assessment and controlled manipulation of the entire LD process, from the natal environment to post-settlement selection, thereby paving the way for novel research avenues in aquatic dispersal ecology. Each tank in the network can independently be controlled for the type of habitat it provides and corridors can flexibly be opened, closed or made directionally permeable. The versatility of the Nexus offers a high degree of experimental flexibility and control to address key issues in spatial meta-population ecology.", "To": ["2020-02-17, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-02-18"], "Project_ID": ["700838"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Spin triplet pairings in ferromagnet Josephson junctions"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SPIN3"], "Technology_Description": "For a long time, the coexistence of conventional superconductivity and ferromagnetism was believed to be impossible. Cooper pairs in normal superconductors are formed by two electrons with antiparallel spins in a singlet configuration while ferromagnets favour parallel alignment of electron spins. In 2001 it was theoretically predicted that under certain conditions both phases could coexist in hybrid structures, giving rise to a race for the discovery of an entirely new kind of superconducting electron pairing state in which the electrons are in the triplet state. The novel hypothesis of this Action relies on the fact that triplet pairs can be formed combining ferromagnets, normal metals and superconductors into hybrid Josephson junctions, and are stable enough to be used to carry spin information in addition to dissipationless charge transfer, which will represent an enormous improvement in comparison to the presently established spin-singlet-based devices.", "To": ["2017-03-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-04-01"], "Project_ID": ["656485"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Cell-type Specific Mechanisms and Functional Consequences of Altered NMDA Receptor Development and Mecp2 Deficiency on Developing Cortical Circuits"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["NMDARETT"], "Technology_Description": "NMDA receptor (NMDAR) dysfunction has been identified in multiple genetic causes of autism and related neurodevelopmental disorders. I recently showed that loss of Mecp2, the cause of Rett syndrome and some cases of autism, differentially affects NMDAR development at cortical synapses on specific cell-types: slowing down the development in excitatory pyramidal neurons and accelerating the maturation in parvalbumin-positive (PV) inhibitory interneurons. Genetic manipulation of NMDAR expression in Mecp2-deficient mice rescued both cortical function and the premature NMDAR maturation in PV cells. Based on these findings, I hypothesize that this cell-type specific disruption of NMDAR development leads to an imbalance in excitation and inhibition in the developing cortical circuits. To test this idea, I will combine single cell genomic and cell-type specific recording techniques to elucidate how Mecp2 controls the development of synaptic receptors and the impact on network function. In Aim 1, I will use cutting-edge techniques for single-cell RNA sequencing and synaptic recordings of NMDAR maturation in cortical cultures to identify novel cell-type specific mechanisms underlying NMDAR development and the regulation by Mecp2. In Aim 2, I will investigate the functional effects of Mecp2 deficiency and altered NMDAR maturation on the development of cortical network activity using two-photon calcium imaging and multi-electrode array (MEA) recordings. As a neuroscientist and neurologist, this training will prepare me for an independent research career addressing the circuit-based defects underlying Rett syndrome and autism. I have the full support of the University of Cambridge and Wellcome Trust Sanger Institute for the proposed research and my career development. This study will improve our understanding of how loss of Mecp2 alters cortical circuits and has the potential to identify novel cell-type specific targets for developing new therapies for Rett syndrome.", "To": ["2018-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-04-01"], "Project_ID": ["700999"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["TEL AVIV UNIVERSITY", "TEL AVIV UNIVERSITY"], "EU_Contribution": ["EUR 1 395 000"], "Project_Title": ["The \u2018Declining Significance of Gender\u2019 Reexamined: Cross-Country Comparison of Individual and Structural Aspects of Gender Inequality"], "Total_Cost": ["EUR 1 395 000"], "Country": ["Israel", "Israel"], "Project_ACR": ["Struct. vs. Individ"], "Technology_Description": "The comparative research of long-term trends largely neglects structural mechanisms of gender inequality, i.e. the gender bias in which jobs and activities are evaluated and rewarded. I argue that as more women become integrated in positions of power, the stronger the role of structural elements is likely to become. However, because these are less visible and amenable to empirical assessment, they are under-researched compared to individual aspects, and are commonly assumed to be gender-neutral. The implication is that the importance of gender as a determinant of economic inequality in the labour market becomes insufficiently acknowledged, and thus difficult to track and eradicate.", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["724351"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITAT DES SAARLANDES", "CONSIGLIO NAZIONALE DELLE RICERCHE", "FONDAZIONE IRCCS ISTITUTO NEUROLOGICO CARLO BESTA", "COLLEGE DE FRANCE", "INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE", "UNIVERSITAETSKLINIKUM BONN", "Academisch Medisch Centrum bij de Universiteit van Amsterdam", "CARDIFF UNIVERSITY", "ASTON UNIVERSITY", "OSLO UNIVERSITETSSYKEHUS HF", "NPI ELECTRONIC GESELLSCHAFT FUER MESS- UND REGELSYSTEME MBH", "H. Lundbeck A/S"], "EU_Contribution": ["EUR 3 924 324,72"], "Project_Title": ["Training, Research and Raising of Public Awareness in Cell Biology and Pathology of Neuroglia"], "Total_Cost": ["EUR 3 924 324,72"], "Country": ["Germany", "Italy", "Italy", "France", "France", "Germany", "Netherlands", "United Kingdom", "United Kingdom", "Norway", "Germany", "Denmark"], "Project_ACR": ["EU-GliaPhD"], "Technology_Description": "The research in which the young scientists of the EU-GliaPhD consortium will be trained is centred on the role of neuron-glia interactions in brain function and pathology.", "To": ["2020-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Corinna Hahn", "Tel.: +49 681 95 92 3362", "Fax: +49 681 95 92 3370", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-12-01"], "Project_ID": ["722053"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["UNIVERSITE DE LIEGE"], "EU_Contribution": ["EUR 160 800"], "Project_Title": ["Exploring the potential applications of live viral vaccine encoded small-hairpin-RNAs in improving both vaccine safety and efficacy through RNA-interference and stimulation of the innate immune system"], "Total_Cost": ["EUR 160 800"], "Country": ["Belgium"], "Project_ACR": ["Super-Vaccine"], "Technology_Description": "Live vaccines represent one of the most important and effective interventions against the spread of viral disease. As such, they are instrumental in addressing ongoing societal challenges in areas such as healthcare and global food security. However, their capacity to genetically recombine with wild type (WT) viruses circulating in the field remains a primary safety concern. Modifying live vaccine strains to reduce such occurrences would be highly desirable from a safety perspective. Also efforts to enhance the intrinsic potency of vaccine strains would be very beneficial. This would facilitate the use of much lower doses, while reducing the manufacturing resources required to meet market needs and the cost of vaccination programs.", "To": ["2020-09-18, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-19"], "Project_ID": ["753696"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Multiple cellular screens using microfluidic droplets"], "Total_Cost": ["EUR 150 000"], "Country": ["France", "France"], "Project_ACR": ["Multiscreen"], "Technology_Description": "Although some biotechnologies have made huge strides e.g. in automation, data generation, or biochemical methods, cell handling still uses antiquated methods that limit the scale at which assays can be performed. Our ERC-funded microfluidics work has lead to cutting-edge microdroplet manipulation tools for cell handling: While working with 3D cell cultures, we have recently shown that we can obtain great increases in both throughput and detail, while reducing the sample use and the machine footprint. In addition to these quantitative leaps, the microfluidic format also allows qualitatively new biological constructs to be explored by making significant steps towards the organ-on-a-chip framework. The current project therefore aims to show how the technologies developed in our lab can function together in an integrated cell screening platform. This will require demonstrating a convincing proof of concept of the hardware, software, and workflow, in addition to demonstrating the added value to different industries.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-07-01"], "Project_ID": ["768790"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["DE MONTFORT UNIVERSITY"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Evolutionary Computation for Dynamic Constrained Optimization Problems"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ECDCOP"], "Technology_Description": "Evolutionary computation (EC), as an efficient tool, has been widely applied to solve different kinds of stationary optimization problems. However, many real-world optimization problems are dynamic constrained optimization problems (DCOPs), where the objective function, constraints, decision variables, and environmental parameters may change over time. At present, very few attempts have been made to investigate this kind of optimization problems in the communities of optimization and EC. This project aims to fill this gap. In this project, we will concentrate on the design, analysis, and applications of EC for DCOPs, including the following five main aspects. Firstly, we will design a set of benchmark dynamic constrained optimization test environments which can resemble real-world scenarios. Secondly, we intend to design standardized performance indicators to evaluate EC methods for DCOPs. Thirdly, based on the standardized dynamic test and evaluation environments, we will design some novel and effective EC methods to solve DCOPs. Fourthly, we will present theoretical analysis of EC with different constraint-handling techniques for DCOPs, with the aim of establishing the theoretical foundation of this area. Finally, applying the developed EC methods to deal with DCOPs in rail networks is also one key aspect of this project. This project has great potentials to fundamentally change the way in which DCOPs are treated, both from a real-world point of view and from the point of view of advancing our theoretical understanding. The research results of this project will be of great interest to academia in many fields and of significant benefit to many industries that involve DCOPs.", "To": ["2017-11-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-12-01"], "Project_ID": ["661327"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["All Aqueous, continuous, Solid-Liquid SYNergisticEXTRACTion of rare earth elements"], "Total_Cost": ["EUR 150 000"], "Country": ["France", "France"], "Project_ACR": ["SYNEXTRACT"], "Technology_Description": "It is a matter of strategic independence for Europe to urgently find processes taking into account environmental and economic issues, when mining and recycling rare earth elements (REE). As of 2015, only 1% of used REE were recycled in the EU and 80% of the mining operations were performed in China, hence representing a major Sword of Damocl\u00e8s for the rest of the world\u2019s economy. With SYNEXTRACT, we propose to leverage on discoveries made (and patented) within ERC-Adv REE-CYCLE, related to new extracting liquid-liquid process. Hence, SYNEXTRACT will try to implement these discoveries in a Solid-liquid extraction process based on Simulated Moving Bed Chromatography. Such process would complement nicely the liquid-liquid one. Indeed, in case of success, it would not only represent a new approach in chromatography, but it would also enable highly flexible purification processes for REEs containing waste streams, that can easily be adapted to various waste stream lixiviates. Due to the high selectivity, it could even be applied to low REE concentration lixiviates. The process flexibility is one of the main bottleneck to enable their recycling as the research and development cost currently necessary to adapt current liquid-liquid extraction processes prohibits it. It should also be mentioned that SYNEXTRACT process would be all aqueous, therefore avoid the use of organic solvent and would drastically reduce process wastes and running costs.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-07-01"], "Project_ID": ["768722"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["BEN-GURION UNIVERSITY OF THE NEGEV"], "EU_Contribution": ["EUR 263 385"], "Project_Title": ["Embodied and Abstract Concepts in Sensory-motor Deprivation"], "Total_Cost": ["EUR 263 385"], "Country": ["Israel"], "Project_ACR": ["EACISD"], "Technology_Description": "How is information organized in the brain? Does our understanding of everyday concepts rely on our perceptual experience, and our ability to sense them? And can this uncover how abstract information is coded in our brains?", "To": ["2018-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-05-01"], "Project_ID": ["654837"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITEIT LEIDEN"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["Voices of Belonging: Minority Identities, Language and Education in the Netherlands"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["Voices of Belonging"], "Technology_Description": "Youth radicalization is potential triggered by a sense of disconnect from society, and experiences of belonging carry important implications for youth identity formation. Language ideologies, policies, and practices in educational contexts send messages for youth regarding their belonging and/or value in society: the voices heard by youth. In addition, youth communicate their sense of belonging and the belonging of others through their words and actions, including their language choices and social affiliations: the voices of youth. The languages used and preferred by youth may or may not correlate with their educational achievement and identity positions. To illuminate the role of language and education in the development of a sense of belonging by youth in culturally and linguistically diverse contexts, this study is based at a large multicultural school in The Hague and addresses, first, how youth experience, enact, and define a sense of belonging and/or exclusion in their linguistic and educational contexts, second, how the language skills, language use choices, and linguistic affiliations of youth intersect with their educational achievements and sense of belonging, and third, the role of gender and ethnicity in the intersecting influences of language, education, and identity for youth in ethnically and linguistically diverse contexts. These questions are addressed through three stages of research: initial observation as vital for contextual depth and adaptation of appropriate questions, a questionnaire to quantitatively evaluate correlations among language, education, and identity, and a final in-depth stage providing student perspectives and supporting the interpretation of the findings. A broader objective of this research is to inform policies and educational programs that serve ethnically and linguistically diverse youth, providing foundations for the development of more culturally responsive pedagogy in the Netherlands and throughout Europe.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["752550"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FUNDACION CIRCE CENTRO DE INVESTIGACION DE RECURSOS Y CONSUMOS ENERGETICOS", "TECHNISCHE UNIVERSITEIT EINDHOVEN", "LABORATOIRE NATIONAL DE METROLOGIE ET D'ESSAIS", "ENEL INGEGNERIA E RICERCA SPA", "ENEL PRODUZIONE SPA", "UNIVERSITY OF STRATHCLYDE", "ORMAZABAL CORPORATE TECHNOLOGY, A.I.E.", "FUNDACION PARA EL FOMENTO DE LA INNOVACION INDUSTRIAL", "HAEFELY TEST AG"], "EU_Contribution": ["EUR 2 819 753,28"], "Project_Title": ["Metrology Excellence Academic Network for Smart Grids"], "Total_Cost": ["EUR 2 819 753,28"], "Country": ["Spain", "Netherlands", "France", "Italy", "Italy", "United Kingdom", "Spain", "Spain", "Switzerland"], "Project_ACR": ["MEAN4SG"], "Technology_Description": "MEAN4SG network aims to educate 11 young researchers in the smart grids metrology field by constructing a training network gathering the whole innovation value chain. The main EU actors in the field of smart grids metrology have worked together, under the umbrella of the European Association of National Metrology Institutes (EURAMET), and relying on the support of the International Electrotechnical Commission (IEC), in order to design a training program coping with the principal R&D challenges related to metrology for smart grids while tackling the shortage of highly-skilled professionals on this area that has been foreseen by the European Commission, the electricity grids industrial sector and the academia.", "To": ["2020-02-29, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-03-01"], "Project_ID": ["676042"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Computational dynamics studies of drug metabolism by P450 enzymes"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["metabolicomp"], "Technology_Description": "Cytochrome P450 enzymes monitor the metabolism of many drugs and small-molecules, as well as selectively catalyze hydrocarbon substrates for application in biotechnology. Drug-drug interactions are critical to the management of safe and effective pharmaceutical treatments. Thus, it is important to better understand the biological functions and activities of P450 enzymes not only to maximize their clinical significance but also to develop broader application in other fields, such as biofuel. There has been significant investment in computational and theoretical studies of P450 enzymes; however, there remains a need for further dynamical calculations to better explore the involvement of the enzyme active site in competing pathways leading to various products. This project aims to determine the role of P450 enzyme in alcohol and alkene formations, compare and contrast heme and non-heme Fe-containing active sites, and model the effect of enzyme environment, using quantum mechanical calculations and inherent dynamics via quasi-classical simulation. The results from this study will help advance the field of computational modeling and its application in biologically important systems.", "To": ["2019-06-20, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-21"], "Project_ID": ["752491"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KUNGLIGA TEKNISKA HOEGSKOLAN", "KUNGLIGA TEKNISKA HOEGSKOLAN"], "EU_Contribution": ["EUR 1 499 180"], "Project_Title": ["Microfiber Electrofluidics for Integrated Molecular Diagnostics"], "Total_Cost": ["EUR 1 499 180"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["iMDx"], "Technology_Description": "\"Diagnosis of an increasing number of diseases (such as HIV, Ebola and antibiotic resistant bacteria) rely on centralized laboratories with specialized instruments and skilled personnel. This type of clinical analysis with long lead times and high cost is inappropriate for point of care diagnostics. Portable, automated, and disposable devices with integrated molecular diagnostics (iMDx), could solve this problem. Such devices, however, basically do not exist today. ", "To": ["2022-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["715268"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["KUNGLIGA TEKNISKA HOEGSKOLAN", "KUNGLIGA TEKNISKA HOEGSKOLAN"], "EU_Contribution": ["EUR 1 499 952"], "Project_Title": ["Greening the Poles: Science, the Environment, and the Creation of the Modern Arctic and Antarctic"], "Total_Cost": ["EUR 1 499 952"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["GRETPOL"], "Technology_Description": "This project investigates how and why environmental concerns have become so important to our conceptions of the polar regions today. Through a historical study of both the Arctic and Antarctic from 1945 to the turn of the past century, the project explores the connections between how environments are described - particularly through the natural sciences and economics - and the judgments made about how those environments should be administered. The key hypothesis of this project is that the process of describing an environment cannot be separated from the process of controlling and managing it. Changing perceptions of concepts such as development, ecological fragility, and wilderness have provided frames for describing and understanding the polar regions. Why has natural resource extraction been deemed appropriate (or even necessary) in some contexts, and wholly forbidden in others? Why did the concept of sustainable development become important during the 1980s? Can we think of scientific research programs as instruments of colonialism? And why did national parks and conservation agreements become politically useful? GRETPOL will produce a new understanding of how far from being the passive frames for human action, environments (in the polar regions but indeed also beyond) are constructed by human agency. As anthropogenic climate change reduces polar ice extent and threatens the entire globe, the question has never been timelier.", "To": ["2022-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-02-01"], "Project_ID": ["716211"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 212 194,80"], "Project_Title": ["Characterizing drivers of intestinal tissue maturation in vitro and in vivo"], "Total_Cost": ["EUR 212 194,80"], "Country": ["Denmark"], "Project_ACR": ["fetISC"], "Technology_Description": "One of the challenges in regenerative medicine is to generate adult intestinal stem cells (ISCs) from human induced pluripotent stem cells (hiPSC) in vitro in defined conditions. This will be important in order to establish intestinal cell transplantation therapies and a platform for neonatal disease modelling. These issues constitute the main goal of the proposal. The current protocols to direct intestinal differentiation from hiPSC impede their suitability for human transplantation purposes either because they require mice as tissue culture incubators (teratoma formation), long exposure to calf serum, or generate cells with fetal properties. The immature fetal intestine is distinct from its mature counterpart most notably by its absence of differentiated secretory lineages. Moreover the precise location and developmental stage from which ISCs are specified in fetal intestine as well as the mechanisms that govern the progression towards an adult epithelium remain to be elucidated. In order to generate adult ISCs from pluripotent sources it is instrumental to decipher the molecular mechanisms driving ISC maturation under physiological conditions. The project will be initiated with the fine mapping of ISC origin in the fetal epithelium using cell tracing techniques. Then I will characterize how fetal ISCs acquire adult properties at the molecular level. In the host laboratory we hypothesize that differentially expressed transcription factors are responsible for the unique characteristics of fetal and adult ISCs. Recently, using gene expression profiling comparing fetal and adult intestinal cells I have identified specific endodermal transcription factors overexpressed in the immature structures. I expect through the modulation of such factors to trigger the intestinal maturation. To ensure the transferability of the results into clinics I will combine studies with murine models and cells from human fetal and adult intestines.", "To": ["2018-01-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-02-01"], "Project_ID": ["656099"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["STICHTING CENTRUM VOOR WISKUNDE EN INFORMATICA", "STICHTING CENTRUM VOOR WISKUNDE EN INFORMATICA"], "EU_Contribution": ["EUR 2 447 439"], "Project_Title": ["Algebraic Methods for Stronger Crypto"], "Total_Cost": ["EUR 2 447 439"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["ALGSTRONGCRYPTO"], "Technology_Description": "Our field is cryptology. Our overarching objective is to advance significantly the frontiers in design and analysis of high-security cryptography for the future generation.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-10-01"], "Project_ID": ["740972"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Ultrasensitive Cartography of vectorial Force Fields at the nanoscale"], "Total_Cost": ["EUR 150 000"], "Country": ["France", "France"], "Project_ACR": ["CARTOFF"], "Technology_Description": "This project aims at developing and disseminating a new class of ultrasensitive and vectorial force field sensors to build the next generation of scanning probes with improved sensitivity and vectorial readout capacity. The vibrations of a singly clamped silicon carbide nanowire (NW) are readout by optical techniques. Its vibrating extremity oscillates in both transverse directions with quasi-degenerated frequencies due to its quasi-cylindrical geometry. When approaching the NW above a sample surface it experiences an additional force field due to the sample-NW interaction which modifies its mechanical properties. The force field can be fully derived by monitoring frequency shifts and eigenmode rotations. The measurement principle was demonstrated during the HQNOM ERC project by monitoring the perturbation of the NW Brownian motion, its random thermal noise in 2D induced by a voltage biased electrostatic tip. An impressive sensitivity to force field gradients varying by less than 1e-18N over the nanometer sized Brownian motion was demonstrated, as well as a fully vectorial readout capacity which is unaccessible to existing 1D force probes. This vectorial sensitivity, combined with the one-millon-fold improvement in force sensitivity over commercial atomic force microscopes is the starting point of the POC project. The objective is to ensure a wide dissemination of this extraordinary vectorial force field sensors and to progress towards an industrial outreach of the apparatus. To do so, a demonstration prototype will be developed and will serve as a workhorse for the second step, the dissemination phase of the apparatus towards a broader scientific and industrial community.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-11-01"], "Project_ID": ["767579"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["THE UNIVERSITY OF NOTTINGHAM", "MATELYS - RESEARCH LAB"], "EU_Contribution": ["EUR 809 451,36"], "Project_Title": ["European industrial doctorate for advanced, lightweight and silent, multifunctional composite structures"], "Total_Cost": ["EUR 809 451,36"], "Country": ["United Kingdom", "France"], "Project_ACR": ["N2N"], "Technology_Description": "Modern aeronautical structures are increasingly made of composite materials due to their well-known benefits. Despite their superior structural characteristics, composite structures exhibit poor dynamic and acoustic isolation levels compared to conventional metallic ones. As a result and in order to maintain the comfort levels in the passenger and payload compartments within acceptable limits, additional acoustic and vibrational isolation technologies (sound packages) are necessary in several transport applications. If non-optimally designed for a certain application, these sound packages can add substantial weight to the structure, compromising the weight benefits gained by the employment of composites.", "To": ["2022-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-03-01"], "Project_ID": ["765472"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["KAROLINSKA INSTITUTET"], "EU_Contribution": ["EUR 173 857,20"], "Project_Title": ["DNA Origami for drug delivery"], "Total_Cost": ["EUR 173 857,20"], "Country": ["Sweden"], "Project_ACR": ["VECTORIGAMI"], "Technology_Description": "The main objective of this project is to produce innovative DNA self-assembled nanostructures with the goal of evolving new approaches for drug delivery. The properties of the DNA nanostructures will be tuned by introducing new elements into the nanostructures improving their versatility and structural integrity. This project will aim to:", "To": ["2017-05-31, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-06-01"], "Project_ID": ["658676"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["FUNDACION BCMATERIALS - BASQUE CENTRE FOR MATERIALS, APPLICATIONS AND NANOSTRUCTURES"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Biological detection with functionalized Magnetic Sensor"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["BIDMAG"], "Technology_Description": "The key goals of the BIDMAG project are: a) the training of a talented experienced researcher, Dr Lopes, in the fast growing field of science, technology and industrial applications of magnetic biosensors, where the host has a critical knowledge and expertise; and, b) design, development and optimisation of cost-efficient smart hybrid surfaces onto magnetic substrates, able to present magnetic response for detecting bacteria. The interdisciplinary training program includes magnetic materials surface modification, fabrication, modelling, characterisation of Magnetoelastic Resonators (MER), surface biofunctionalisation and detection of the biological parameters, which will enhance and broaden her expertise and increase her exposure to both academic and industrial collaborations. She is a talented researcher who has gained much expertise in interdisciplinary area of electroactive polymer composites during her postgraduate career. This background is invaluable for applying in preparation and characterisation techniques of smart materials. To further her career in magnetic biosensors Dr Lopes needs to gain expertise in functional materials and magnetic characterisation, fields in which BCMaterials has a world-recognised expertise. Additionally, through secondments at academic and industrial co-hosts, at ACREO and VAC, respectively, she will gain additional training in: industrial production of MER and Optimization of compact and commercial MER interrogation systems.The impact of the project will be multidisciplinary, since it has applications ranging from environmental monitorization and food quality control to fast medical diagnostics. Besides, to further boost her career, Dr Lopes needs to increase her supervision and teaching experience, gain project and intellectual property management expertise, research funding and proposal writing skills. Multidisciplinary activities will assist her in acquiring necessary competences and reaching professional maturity.", "To": ["2018-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2016-05-01"], "Project_ID": ["701852"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITY OF NEWCASTLE UPON TYNE", "UNIVERSITY OF NEWCASTLE UPON TYNE"], "EU_Contribution": ["EUR 1 485 642,50"], "Project_Title": ["Confidentiality-preserving Security Assurance"], "Total_Cost": ["EUR 1 485 642,50"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["CASCAde"], "Technology_Description": "\"This proposal aims to create a new generation of security assurance. It investigates whether one can certify an inter-connected dynamically changing system in such a way that one can prove its security properties without disclosing sensitive information about the system's blueprint. ", "To": ["2022-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["716980"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["THE UNIVERSITY OF NOTTINGHAM", "THE UNIVERSITY OF NOTTINGHAM"], "EU_Contribution": ["EUR 149 932"], "Project_Title": ["ImmortaSTEM: Transient Immortalisation for Patient Stem Cell Expansion and Therapeutic Application"], "Total_Cost": ["EUR 149 932"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["ImmortaSTEM"], "Technology_Description": "Under an ERC Advanced Grant, and subsequent PoC grant, Professor Shakesheff's team have invented a new intracellular delivery system that overcomes a problem in drug delivery in stem cell culture as well as regenerative medicine and other therapeutic approaches. The system, called GAG-binding enhanced transduction (GET), enables intracellular delivery of proteins, nucleic acids and particles into cells that resist other non-viral strategies. The work under ERC Advanced Grant and PoC funding has allowed exemplification of the delivery of proteins that promote pluripotency or differentiation, and delivery and expression of mRNA ", "To": ["2018-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["754745"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["THE UNIVERSITY OF EDINBURGH", "THE UNIVERSITY OF EDINBURGH", "INTERACTIVE SCIENTIFIC LTD"], "EU_Contribution": ["EUR 149 951"], "Project_Title": ["A Software Interface for Interactive Ensemble-Based Drug Design"], "Total_Cost": ["EUR 149 951"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom"], "Project_ACR": ["iEBDD"], "Technology_Description": "The ERC project EBDD was funded to bring about a new generation of computer algorithms to implement accurate molecular simulations of biomolecules and their interactions with man-made molecules that are potential new therapeutics. First results from the EBDD project (ERC-StG-2013-336289) indicate the ground-breaking potential of the academic software generated for supporting pre-clinical drug discovery R&D in the pharmaceutical and biotech sectors. Building on these early results from the EBDD project, this proposal aims to prototype an innovative interactive human-computer drug design workflow that will enhance the value of the academic software, and enable new types of R&D processes (hit discovery, hit-to-lead and lead-optimisation) in a preclinical drug discovery environment. ", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-07-01"], "Project_ID": ["754654"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["CONSIGLIO NAZIONALE DELLE RICERCHE", "CONSIGLIO NAZIONALE DELLE RICERCHE", "UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA", "FUNDACIO INSTITUT DE CIENCIES FOTONIQUES"], "EU_Contribution": ["EUR 2 381 875"], "Project_Title": ["Composite integrated photonic platform by femtosecond laser micromachining"], "Total_Cost": ["EUR 2 381 875"], "Country": ["Italy", "Italy", "Italy", "Spain"], "Project_ACR": ["CAPABLE"], "Technology_Description": "The quantum technology revolution promises a transformational impact on the society and economics worldwide. It will enable breakthrough advancements in such diverse fields as secure communications, computing, metrology, and imaging. Quantum photonics, which recently received an incredible boost by the use of integrated optical circuits, is an excellent technological platform to enable such revolution, as it already plays a relevant role in many of the above applications. However, some major technical roadblocks needs to be overcome. Currently, the various components required for a complete quantum photonic system are produced on very different materials by dedicated fabrication technologies, as no single material is able to fulfil all the requirements for single-photon generation, manipulation, storage and detection. This project proposes a new hybrid approach for integrated quantum photonic systems based on femtosecond laser microfabrication (FLM), enabling the innovative miniaturization of various components on different materials, but with a single tool and with very favourable integration capabilities. ", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2017-10-01"], "Project_ID": ["742745"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["HEINRICH-HEINE-UNIVERSITAET DUESSELDORF"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Development and characterization of an ultra-high performance mobile optical atomic clock based on lattice-trapped atoms"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["Mobiclock"], "Technology_Description": "New types of atomic clocks, based on laser-cooled and trapped atoms interrogated by optical lasers, are changing the paradigm for precision measurement of time and frequency. Optical lattice clocks, which provide superb frequency stability, are today complex systems, able to operate only in well-controlled laboratory environments and require continuous personnel intervention. The proposed activity aims to realize the transition from today's laboratory systems into mature mobile instruments. The result of this transition opens outstanding and transformational future fields of application: world-wide accuracy comparisons of stationary clocks, high-precision tests of General Relativity, and mapping of the Earth gravitational potential via relativistic geodesy.", "To": ["2018-04-30, Grant Agreement terminated |"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["707864"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERZITA PAVLA JOZEFA SAFARIKA V KOSICIACH", "OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN", "THE TRUSTEES OF BOSTON UNIVERSITY", "THE REGENTS OF THE UNIVERSITY OF CALIFORNIA", "THE GENERAL HOSPITAL CORPORATION", "OREGON HEALTH AND SCIENCE UNIVERSITY"], "EU_Contribution": ["EUR 351 000"], "Project_Title": ["Adaptation, learning and training for spatial hearing in complex environments"], "Total_Cost": ["EUR 441 000"], "Country": ["Slovakia", "Austria", "United States", "United States", "United States", "United States"], "Project_ACR": ["ALT"], "Technology_Description": "In everyday situations, humans are exposed to multiple concurrent stimuli in complex, continuously changing environments. To correctly extract relevant information, they adapt their processing to reflect the specifics of the current scene, and they learn from previous experience to improve the perceptual strategies used. The current project proposes to perform a series of behavioral experiments, brain imaging studies, and computational modeling 1) to study the auditory mechanisms of adaptation to new reverberant environments for speech processing, sound localization, and learning of new phonetic categories, and 2) to study how attention and mechanisms of implicit and explicit learning are used to cope with complex listening environments. The results will be important, e.g., for development of new prosthetic devices and new virtual reality technologies. Here, they will be used to develop a brain training game that can improve impaired listeners\u2019 performance in complex environments. An additional goal of the proposal is to obtain new knowledge and skills related to studying human perceptual processes and the corresponding neural mechanisms. Skills to perform sensory learning research, psychophysics, non-invasive brain imaging (EEG and fMRI), and computational modeling will be exchanged during the secondments. Also, a series of workshops will be organized to train new researchers to perform research in computational and cognitive neuroscience, with additional goal of enhancing the exchange of information among participants and sharing new results obtained in this project. The project consortium consists of academic, research, medical, and small enterprise organizations based in the EU and USA. The participants have complementary skills necessary to achieve all the defined goals. Their collaboration on this project will result in strengthening of the European Research Area and in establishing new long-term collaborations between EU and US researchers.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Slovakia"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["691229"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["UNIVERSIDAD DE GRANADA", "ISTITUTO NAZIONALE DI GEOFISICA E VULCANOLOGIA", "ILMATIETEEN LAITOS", "EISCAT SCIENTIFIC ASSOCIATION", "UNIVERSITAET BREMEN", "HELSINGIN YLIOPISTO", "MARINE INSTITUTE", "UNIVERSITA DEGLI STUDI DELLA TUSCIA", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES"], "EU_Contribution": ["EUR 1 997 990"], "Project_Title": ["COOPERATION OF RESEARCH INFRASTRUCTURES TO ADDRESS GLOBAL CHALLENGES IN THE ENVIRONMENT FIELD"], "Total_Cost": ["EUR 1 997 990"], "Country": ["Spain", "Italy", "Finland", "Sweden", "Germany", "Finland", "Ireland", "Italy", "France"], "Project_ACR": ["COOP_PLUS"], "Technology_Description": "The COOP+ project is motivated by the interest of several Research Infrastructures in Europe to benefit from extending international collaboration with other Research Infrastructures in their areas of expertise at global, worldwide level.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["INFRASUPP-6-2014 - International cooperation for research infrastructures"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2016-03-01"], "Project_ID": ["654131"], "Call_for_Proposal": ["H2020-INFRASUPP-2014-2"]}, -{"Partners": ["COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "KAROLINSKA INSTITUTET", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSITE DE LIEGE", "UCB PHARMA SA", "ASTRAZENECA AB", "SANOFI-AVENTIS DEUTSCHLAND GMBH"], "EU_Contribution": ["EUR 3 948 843,96"], "Project_Title": ["ISOTOPIC LABELING FOR DRUG INNOVATION"], "Total_Cost": ["EUR 3 948 843,96"], "Country": ["France", "United Kingdom", "Sweden", "France", "Belgium", "Belgium", "Sweden", "Germany"], "Project_ACR": ["ISOTOPICS"], "Technology_Description": "Excessive attrition rates during clinical trials dramatically impact on Drug Discovery and Development (DDD). Absorption, Distribution, Metabolism and Excretion studies carried out on larger series of drug candidates at an earlier stage of the DDD timeline and evaluation of drug efficacy through better assessment of pharmacokinetic/pharmacodynamic relationships, target engagement and receptor occupancy are critically important approaches for de-risking drug innovation since they facilitate early identification of the candidates that display the best in vivo profile. When successfully implemented, this strategy can accelerate the discovery of new therapeutic solutions to existing and emerging diseases, and enhance European pharmaceutical innovation. For implementation, large sets of isotopically-labeled molecules are required and consequently, a huge revival of labeling techniques is urgently needed. Another crucial issue is the scarcity of expert radiochemists in Europe and the lack of first class training programs in this inter-disciplinary field merging chemistry, radiochemistry and medicinal chemistry. The aims of ISOTOPICS are: i) to train the next generation of European chemists with expertise in isotopic labeling and advanced medicinal chemistry through a first-class taught and research training program combined with a highly interactive secondments plan; ii) to develop innovative and general isotopic labeling chemistry and radiochemistry to streamline the synthesis of labeled small-molecule drugs and biologics; iii) to work closely with the European pharmaceutical industry to apply the new labeling methods to drugs currently in development in order to provide solutions to the most pressing problems in drug innovation. This highly interdisciplinary project is expected to have a profound beneficial impact on drug innovation in Europe by providing novel efficient techniques and new experts in the fields of labeling and medicinal chemistries.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-01-01"], "Project_ID": ["675071"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "ARISTOTELIO PANEPISTIMIO THESSALONIKIS", "INSILICO BIOTECHNOLOGY AG", "PROCESS SYSTEMS ENTERPRISE LIMITED", "SILICOLIFE LDA", "HUMBOLDT-UNIVERSITAET ZU BERLIN", "PROTATOUANS - ETAIREIA EREYNAS VIOTECHNOLOGIAS MONOPROSOPI ETAIREIA PERIORISMENIS EYTHINIS", "RIJKSUNIVERSITEIT GRONINGEN", "UNIVERSITAETSKLINIKUM AACHEN", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE"], "EU_Contribution": ["EUR 3 805 423,20"], "Project_Title": ["Systematic Models for Biological Systems Engineering Training Network"], "Total_Cost": ["EUR 3 805 423,20"], "Country": ["United Kingdom", "Spain", "Greece", "Germany", "United Kingdom", "Portugal", "Germany", "Greece", "Netherlands", "Germany", "Switzerland"], "Project_ACR": ["SyMBioSys"], "Technology_Description": "Mathematical, computational models are central in biomedical and biological systems engineering; models enable (i) mechanistically justifying experimental results via current knowledge and (ii) generating new testable hypotheses or novel intervention methods. ", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["675585"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["UNIVERSIDAD POLITECNICA DE MADRID", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "OFFICE NATIONAL D'ETUDES ET DE RECHERCHES AEROSPATIALES", "DEUTSCHES ZENTRUM FUER LUFT - UND RAUMFAHRT EV", "INSTITUT VON KARMAN DE DYNAMIQUE DES FLUIDES", "NUMERICAL MECHANICS APPLICATIONS INTERNATIONAL SA", "AIRBUSGROUP LIMITED", "KATHOLIEKE UNIVERSITEIT LEUVEN", "KUNGLIGA TEKNISKA HOEGSKOLAN"], "EU_Contribution": ["EUR 3 900 365,28"], "Project_Title": ["Stability and Sensitivity Methods for Industrial Design"], "Total_Cost": ["EUR 3 900 365,28"], "Country": ["Spain", "United Kingdom", "United Kingdom", "France", "Germany", "Belgium", "Belgium", "United Kingdom", "Belgium", "Sweden"], "Project_ACR": ["SSeMID"], "Technology_Description": "The increasing environmental awareness of the European society has been always present in the aeronautical community, industry and research centres, having a definite influence on the way the aircraft of the future should be. In this line, the ACARE Vision for 2020, a Group of Renowned Personalities in the aeronautical field, has formulated a clear set of requirements for civil transport aircraft operations in order to reach the following specific environmental goals: halving perceived aircraft noise, 50% cut in CO2 emissions per passenger-km and 80% cut in NOx emissions.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["675008"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["UNIVERSIDAD DE ZARAGOZA"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Controlling Cell Fate through Smart Nanoheaters"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["CONFINES"], "Technology_Description": "Achieving the control of cellular processes is one of the most intriguing challenges in cell biology and medicine. Forefront approaches based on bioengineered nanoparticles might have the potential to target specific cell pathways, thus controlling downstream cell activities in a space and time selective fashion. The present project aims to develop and to validate a smart nanovectorable to activate a specific cell signalling and, on demand, to induce heat mediated cell death of nanovector targeted cells. As proof of concept, CONFINES is conceived to target the Wnt canonical pathway, one of the most studied and fascinating cell signalling, which orchestrates central mechanisms that govern cell proliferation, polarity and stem cell fate. To achieve the proposed objectives, a controlled synthetic approach will tailor Wnt ligands on magnetic nanoparticles, combining targeting and magnetic properties in a uniquenanovector. Owing to its chemico-physical features, NanoWnt will enable complete control of the cell signalling, and it will operate in vitro (human cell cultures) and in vivo (the aquatic invertebrateHydra vulgaris), in a dual mode: i) as an activator of the canonical Wnt pathway in those contexts where it is inactive ii) or upon exposure to a magnetic field, as a nanoheater, enabling specific cell ablation by hyperthermia. From a technological point of view, the project will advance basic knowledge on thermal ablation (via magnetic hyperthermia) and holds promises for translational medicine, providing a breakthrough tool to shape cell fate of nanovector receiving cells. Furthermore, combining diverse expertise, CONFINES will offer the applicant advanced and multidisciplinarytraining in the field of nanomaterial synthesis, characterization and functionalisation as well as in hyperthermia technology, which will complement his current skills based on nanobiotechnology and cellular/molecular biology.", "To": ["2017-09-08, Grant Agreement terminated |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-09"], "Project_ID": ["657566"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["ISTITUTO NAZIONALE DI FISICA NUCLEARE"], "EU_Contribution": ["EUR 180 277,20"], "Project_Title": ["The anomalous magnetic moment of the muon as a benchmark for New Physics Searches"], "Total_Cost": ["EUR 180 277,20"], "Country": ["Italy"], "Project_ACR": ["Gm2m"], "Technology_Description": "The anomalous magnetic moment of the muon has revealed its potential to be the cornerstone for beyond the Standard Model searches, since it is one of the most accurately measured quantity in particle physics. Being the Standard Model in a nutshell, is at the cutting edge of the developments in the field. A persistent discrepancy between theory and experiment exists and has triggered two new challenging and expensive experiments at FermiLab and at JPARC which will push the measurement of that quantity to an unprecedented precision of a 0.14 ppm. At that level, differences beyond theoretical uncertainties among theory collaborations are limiting the theory precision. Thus, they must be resolved with an exceptional precision as well to sort out whether the observed departure is and indication of New Physics and to correspond the enormous experimental effort. The project Gm2m aims to provide the theoretical framework to coordinate and elaborate on a continuous and robust update of the Standard Model prediction of this observable through the use of 1) a user-friendly and modern web-page interface that should allow the community to keep track of the exact state-of-the-art calculation and 2) a new reassessment with unparalleled precision of the uncertainties of the Standard Model. The project Gm2m will consider a set of novel approaches for finding a solution to the current theoretical puzzles, which also demands an exhaustive scrutiny of the theoretical uncertainties at the 0.1ppm level. This effort should culminate in a most robust Standard Model prediction up to date. ", "To": ["2019-06-30, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations"], "From": ["2017-07-01"], "Project_ID": ["702243"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["ISTITUTO NAZIONALE DI FISICA NUCLEARE", "STIFTUNG DEUTSCHES ELEKTRONEN-SYNCHROTRON DESY", "OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN", "THE HENRYK NIEWODNICZANSKI INSTITUTE OF NUCLEAR PHYSICS, POLISH ACADEMY OF SCIENCES", "UNIVERZITA KARLOVA", "INSTITUT JOZEF STEFAN", "MIDDLE EAST TECHNICAL UNIVERSITY", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "INSTITUTO DE FISICA DE ALTAS ENERGIAS", "NARODOWE CENTRUM BADAN JADROWYCH", "QUEEN MARY UNIVERSITY OF LONDON", "SCIENCE AND TECHNOLOGY FACILITIES COUNCIL", "COSTRUZIONI APPARECCHIATURE ELETTRONICHE NUCLEARI C.A.E.N. SPA", "INTER-UNIVERSITY RESEARCH INSTITUTE CORPORATION, HIGH ENERGY ACCELERATOR RESEARCH ORGANISATION", "NATIONAL UNIVERSITY CORPORATION THEUNIVERSITY OF TOKYO"], "EU_Contribution": ["EUR 2 308 500"], "Project_Title": ["Japan and Europe Network for Neutrino and Intensity Frontier Experimental Research"], "Total_Cost": ["EUR 2 308 500"], "Country": ["Italy", "Germany", "Austria", "Poland", "Czech Republic", "Slovenia", "Turkey", "France", "France", "Spain", "Poland", "United Kingdom", "United Kingdom", "Italy", "Japan", "Japan"], "Project_ACR": ["JENNIFER"], "Technology_Description": "European particle physics groups interested in searching signals of new physics both with neutrinos, at T2K experiment, and at the intensity frontier, with the Belle-II experiment at the SUPERKEKB machine, want to share between them and with KEK laboratory their knowledge in data analysis and detector technologies. Such knowledge sharing will enhance skills and competences of all participants, will allow Europe to play a primary role in the search for deviations from the actually known fundamental physics in the flavour sector and, last but not least, will produce an unprecedented collaboration with japanese scientists on the ground of dissemination and outreach.", "To": ["2019-03-31, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-04-01"], "Project_ID": ["644294"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["STIFTUNG DEUTSCHES ELEKTRONEN-SYNCHROTRON DESY", "FORSCHUNGSZENTRUM JULICH GMBH", "B.P. KONSTANTINOV PETERSBURG NUCLEAR PHYSICS INSTITUTE", "RUSSIAN RESEARCH CENTRE KURCHATOV INSTITUTE", "FACILITY FOR ANTIPROTON AND ION RESEARCH IN EUROPE GMBH", "JOINT INSTITUTE FOR NUCLEAR RESEARCH", "HELMHOLTZ-ZENTRUM GEESTHACHT ZENTRUM FUR MATERIAL- UND KUSTENFORSCHUNG GMBH", "TECHNISCHE UNIVERSITAET MUENCHEN", "INSTITUT MAX VON LAUE - PAUL LANGEVIN", "EUROPEAN SPALLATION SOURCE ERIC", "EUROPEAN SPALLATION SOURCE ESS AB", "INSTALLATION EUROPEENNE DE RAYONNEMENT SYNCHROTRON", "EUROPEAN X-RAY FREE-ELECTRON LASERFACILITY GMBH", "ASSOCIATION INTERNATIONALE EXTREME-LIGHT-INFRASTRUCTURE DELIVERY CONSORTIUM", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "INSTITUTE OF APPLIED PHYSICS, RUSSIAN ACADEMY OF SCIENCES", "EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH", "Budker Institute of Nuclear Physics of SB RUS", "FEDERAL SCIENTIFIC RESEARCH CENTRECRYSTALLOGRAPHY AND PHOTONICS OF THE RUSSIAN ACADEMY OF SCIENCES", "LUNDS UNIVERSITET"], "EU_Contribution": ["EUR 1 696 250"], "Project_Title": ["Connecting Russian and European Measures for Large-scale Research Infrastructures"], "Total_Cost": ["EUR 1 696 250"], "Country": ["Germany", "Germany", "Russia", "Russia", "Germany", "Russia", "Germany", "Germany", "France", "Sweden", "Sweden", "France", "Germany", "Belgium", "France", "Russia", "Switzerland", "Russia", "Russia", "Sweden"], "Project_ACR": ["CREMLIN"], "Technology_Description": "This CREMLIN proposal is to foster scientific cooperation between the Russian Federation and the European Union in the development and scientific exploitation of large-scale research infrastructures. It has been triggered by the recent so-called megascience projects initiative launched by and in the Russian Federation which is now very actively seeking European integration. The proposed megascience facilities have an enormous potential for the international scientific communities and represent a unique opportunity for the EU to engage in a strong collaborative framework with the Russian Federation.", "To": ["2018-08-31, ongoing project |"], "Meta": [""], "Topic_s": ["INFRASUPP-6-2014 - International cooperation for research infrastructures"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Research Organisations", "Other", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["654166"], "Call_for_Proposal": ["H2020-INFRASUPP-2014-2"]}, -{"Partners": ["ISTITUTO NAZIONALE DI FISICA NUCLEARE", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "STIFTUNG DEUTSCHES ELEKTRONEN-SYNCHROTRON DESY", "UNIVERSITAT POLITECNICA DE VALENCIA", "ATOS SPAIN SA", "CONSORZIO INTERUNIVERSITARIO RISONANZE MAGNETICHE DI METALLO PROTEINE", "ISTITUTO NAZIONALE DI ASTROFISICA", "LABORATORIO DE INSTRUMENTACAO E FISICA EXPERIMENTAL DE PARTICULAS", "KARLSRUHER INSTITUT FUER TECHNOLOGIE", "UNIVERSITEIT UTRECHT", "EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH", "T-SYSTEMS INTERNATIONAL GMBH", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "FONDAZIONE CENTRO EURO-MEDITERRANEO SUI CAMBIAMENTI CLIMATICI", "Istituto Centrale per il Catalogo Unico delle biblioteche italiane e per le informazioni bibliografiche", "SANTER REPLY SPA", "AKADEMIA GORNICZO-HUTNICZA IM. STANISLAWA STASZICA W KRAKOWIE", "INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK", "STICHTING EGI", "INDRA SISTEMAS SA", "CONSIGLIO NAZIONALE DELLE RICERCHE", "SCIENCE AND TECHNOLOGY FACILITIES COUNCIL", "CESNET ZAJMOVE SDRUZENI PRAVNICKYCH OSOB", "ISTITUTO NAZIONALE DI GEOFISICA E VULCANOLOGIA", "RUDER BOSKOVIC INSTITUTE", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES"], "EU_Contribution": ["EUR 11 138 114"], "Project_Title": ["INtegrating Distributed data Infrastructures for Global ExplOitation"], "Total_Cost": ["EUR 11 565 239"], "Country": ["Italy", "Spain", "Germany", "Spain", "Spain", "Italy", "Italy", "Portugal", "Germany", "Netherlands", "Switzerland", "Germany", "France", "Italy", "Italy", "Italy", "Poland", "Poland", "Netherlands", "Spain", "Italy", "United Kingdom", "Czech Republic", "Italy", "Croatia", "France"], "Project_ACR": ["INDIGO-DataCloud"], "Technology_Description": "The INDIGO-DataCloud project (INDIGO for short) aims at developing a data/computing platform targeted at scientific communities, deployable on multiple hardware, and provisioned over hybrid (private or public) e-infrastructures. This platform will be built by leading European developers, resource providers, e-infrastructures and scientific communities in order to ensure its successful exploitation and sustainability.", "To": ["2017-09-30, closed project"], "Meta": [""], "Topic_s": ["EINFRA-1-2014 - Managing, preserving and computing with big research data"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations"], "From": ["2015-04-01"], "Project_ID": ["653549"], "Call_for_Proposal": ["H2020-EINFRA-2014-2"]}, -{"Partners": ["UNIVERSITE D'AIX MARSEILLE", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "UNIVERSITE CATHOLIQUE DE LOUVAIN", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSITAIR MEDISCH CENTRUM UTRECHT", "AALTO-KORKEAKOULUSAATIO", "SAINT PETERSBURG NATIONAL RESEARCH UNIVERSITY OF INFORMATION TECHNOLOGIES, MECHANICS AND OPTICS", "THE AUSTRALIAN NATIONAL UNIVERSITY", "MULTIWAVE TECHNOLOGIES AG", "MR COILS BV"], "EU_Contribution": ["EUR 3 945 346,25"], "Project_Title": ["MetaMaterials antenna for ultra-high field MRI"], "Total_Cost": ["EUR 4 582 346,25"], "Country": ["France", "France", "Belgium", "France", "Netherlands", "Finland", "Russia", "Australia", "Switzerland", "Netherlands"], "Project_ACR": ["M-CUBE"], "Technology_Description": "M-Cube aims at changing the paradigm of High-Field MRI and Ultra High-Field antennas to offer a much better insight on the human body and enable earlier detection of diseases. Our main objective is to go beyond the limits of MRI clinical imaging and radically improve spatial and temporal resolutions. The clinical use of High-field MRI scanners is drastically limited due to the lack of homogeneity and to the Specific Absorption Rate (SAR) of the Radio Frequency (RF) fields associated with the magnetic resonance.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-01-2016-2017 - FET-Open research and innovation actions"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["736937"], "Call_for_Proposal": ["H2020-FETOPEN-1-2016-2017"]}, -{"Partners": ["UNIVERSITE PARIS XII VAL DE MARNE", "THE UNIVERSITY OF LIVERPOOL", "FUNDACION DE INVESTIGACION DEL CANCER DE LA UNIVERSIDAD DE SALAMANCA", "STICHTING KATHOLIEKE UNIVERSITEIT", "INSTYTUT BIOLOGII DOSWIADCZALNEJ IM. M. NENCKIEGO POLSKIEJ AKADEMII NAUK", "ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS", "UNIVERSITAT AUTONOMA DE BARCELONA", "SCREENCELL"], "EU_Contribution": ["EUR 3 991 096,25"], "Project_Title": ["3-O-sulfated heparan sulfate translocation in altered membrane biology: A newstrategy for early population screening and halting Alzheimer\u2019s neurodegeneration"], "Total_Cost": ["EUR 3 991 096,25"], "Country": ["France", "United Kingdom", "Spain", "Netherlands", "Poland", "France", "Spain", "France"], "Project_ACR": ["ArrestAD"], "Technology_Description": "ArrestAD proposes a novel and visionary thinking resulting from the demonstration of the central role of a particular heparan sulfate species at the intracellular level in neurons and in circulating cells in the molecular pathology of Alzheimer\u2019s disease (AD). AD is a societal challenge for which there is neither prevention nor possible cure. Research in the field has long been refining classic concepts based on the aggregation of A\u03b2 and tau through initial seeding and then spreading. Our vision is different and based on the demonstration that tau abnormal phosphorylation and aggregation is triggered by the interaction of tau with heparan sulfates internalized in neurons and circulating cells only in AD [UPEC R.1; P.1,2]. Based in this new concept, ArrestAD will establish links between AD genetics, disease hallmarks, and altered traffic and intracellular accumulation of heparan sulfates to generate new knowledge underpinning the development of new strategies for detection and treatment of AD. This will open to radically new technologies addressing two major objectives: 1) proving that specific and early diagnosis of AD is possible in circulating cells, and 2) demonstrating that a new class of drug candidates are able to preventing and/or arresting AD-neurodegeneration. To reach these objectives, ArrestAD brings together internationally recognized experts in AD clinics and diagnosis, in heparan sulfate biology, transcriptomics, interactomics, carbohydrate chemistry, enzymology, cell biology, animal experimentation with AD models, and a SME specialized in the development of diagnosis kits using circulating cells. The high-risk character of this joint science and technology research is offset by the multidisciplinary nature of the Consortium and the high socio-economic gain resulting from success. Based in this technology, we will build a diverse portfolio of future projects that will result in a long-term benefit for citizens, economy and society.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-01-2016-2017 - FET-Open research and innovation actions"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["737390"], "Call_for_Proposal": ["H2020-FETOPEN-1-2016-2017"]}, -{"Partners": ["COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["HIV/SIV exploits DCs in mucosal infection: mechanisms of transmission and modulation by semen associated factors"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["DCmucoHIV"], "Technology_Description": "Worldwide a large proportion of all new cases of HIV-1 infection are due to anal sexual intercourse, being the anal/rectal as well as distal colonic mucosa a site of viral uptake and entry. I recently demonstrated that intestinal lamina propria resident DCs migrate towards and extend cellular processes between the tight junctions of columnar epithelium through a CCR5-dependent mechanism, take up R5 but not X4 HIV-1, and then transfer infection to susceptible T cells. Although in mice CX3CR1+DCs are deputed to shuttle microbial antigens, there is no clear idea on which subsets of DCs are located in the human GI tract, are involved in HIV infection and contribute to virus spread, its presentation or possibly to its reservoir. Moreover, the ability of DCs to shuttle the virus across the mucosa may be largely modulated by components of semen, the natural vehicle of HIV during sexual transmission.", "To": ["2017-06-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2015-07-01"], "Project_ID": ["658277"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI MACERATA", "PHILIPS ELECTRONICS NEDERLAND B.V.", "KATHOLIEKE UNIVERSITEIT LEUVEN"], "EU_Contribution": ["EUR 1 527 991,20"], "Project_Title": ["HEalth related Activity Recognition system based on IoT \u2013 an interdisciplinary training program for young researchers"], "Total_Cost": ["EUR 1 527 991,20"], "Country": ["Italy", "Netherlands", "Belgium"], "Project_ACR": ["HEART"], "Technology_Description": "A current trend in healthcare involves the prevention of chronic diseases by changing behaviour towards more healthy lifestyle choices. This is supported by the increased use of wearable sensors and Internet of Things (IoT) devices. Human activity recognition and vital sign monitoring play a significant role in tailoring personal health and behaviour change coaching solutions to each individual, but pose a number of technical, legal, and socio-economic issues, which must be solved to enable a commercial viable solution.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2017 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["766139"], "Call_for_Proposal": ["H2020-MSCA-ITN-2017"]}, -{"Partners": ["THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS", "THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS"], "EU_Contribution": ["EUR 1 498 052"], "Project_Title": ["The Ethics of Oil: Finance Moralities and Environmental Politics in the Global Oil Economy"], "Total_Cost": ["EUR 1 498 052"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["ENERGY ETHICS"], "Technology_Description": "In October 2014, the Chairman of the Bank of England Mark Carney warned that many oil reserves cannot be developed. If so, they would contribute so significantly to increased greenhouse gas emissions that international targets to avoid dangerous levels of global warming would be exceeded. However, stock valuations of oil companies assume that all proven and probable reserves can indeed be produced. Amounting to a potentially enormous debt overhang, the Bank of England has launched an enquiry into the threat of a crisis similar to the subprime mortgage crash, known as the \u2018carbon bubble\u2019. This looming crisis with its \u2018stranded assets\u2019 raises urgent questions about the conflicting dynamics between finance moralities and environmental politics at a time of oil dependency and an uncertain climate future. Grounded in ethnographic fieldwork with oil companies in the US and Norway, energy analysts in the UK and the US, and fossil fuel divestment movements in Germany and the UK, ENERGY ETHICS will develop a new framework for understanding the relationship between oil, money and climate change that counters the prevalent tendency to interpret these issues through aggregated normative systemic analysis only. Taking its starting point in people\u2019s own perceptions of and direct involvement in the oil economy, it will offer a major step forward in understanding how people in positions of influence within the oil economy make financial and ethical valuations of oil. This will contribute to public stakeholder dialogue and wider transdisciplinary engagements. Focusing on oil and its financialization, ENERGY ETHICS has three main research objectives: 1) to examine how people positioned strategically in relation to the global production of oil conceptualise and influence the oil market; 2) to understand the linkages and frictions between these different valuations of oil; and 3) to investigate how oil valuations relate to political reforms and new climate economic initiatives.", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["715146"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["FUNDACIO INSTITUT DE CIENCIES FOTONIQUES"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Visualising Chromatin Structure and Dynamics at the Nanometre Scale with Super-Resolution Fluorescence Microscopy"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["VCSD"], "Technology_Description": "Recently, it has become evident that the spatial organization of chromatin within nuclei is a key factor that can regulate gene silencing and expression. This organization is particularly important in pluripotent stem cells that differentiate into all cell types of the body through chromatin remodelling coupled to altered gene expression. Therapeutic use of these cells demands precise control over chromatin structure to direct differentiation. However, chromatin structure remains poorly resolved due to the nanometre length scales involved and limitations of low spatial resolution, poor signal-to-noise and ensemble averaging in existing methods. VCSD utilizes cutting-edge super-resolution fluorescence microscopy (SRFM) that overcomes these limitations. VCSD will, for the first time: 1) visualize global, 3D chromatin nanoscale structure in individual cells during differentiation; and 2) correlate the dynamics of local chromatin restructuring with the silencing of a central pluripotency gene. The proposed Marie Curie Fellow, Jason Otterstrom, PhD Harvard Biophysics, has extensive experience in fluorescence microscopy applied to biological systems. The host lab supervisor, Dr. Loza-Alvarez, is an expert in SRFM, at the Institute for Photonic Sciences, Barcelona. A secondment is planned in the lab of Dr. Cosma, an expert in the genetic mechanisms controlling pluripotency, at the Barcelona Center for Genomic Regulation. The combined expertise of the fellow and host labs is uniquely suited to establish VCSD as a novel framework for characterizing chromatin structure. The methodology developed is anticipated to be adopted by researchers in stem cell and chromatin biology fields, thereby reinforcing Europe\u2019s global reputation in scientific innovation. The Fellowship will enable Jason to pursue applications of the chromatin structural metrics determined here as an independent biophysical researcher, with the long-term goal of commercializing a stem cell classification system.", "To": ["2018-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2016-04-01"], "Project_ID": ["656873"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["HELSINGIN YLIOPISTO"], "EU_Contribution": ["EUR 179 325,60"], "Project_Title": ["The developmental and evolutionary basis of human intersubjectivity"], "Total_Cost": ["EUR 179 325,60"], "Country": ["Finland"], "Project_ACR": ["DEVOLEMPA"], "Technology_Description": "This research aims to unravel the ontogenetic and phylogenetic roots of the unique human intersubjectivity. Empathy forms the basis of intersubjectivity. In the first part of the research, we address empathy development in young, 6-16-month-old infants who engage in interactive, intentional communication but do not yet cognitively represent others\u2019 mental states. They may, however, attend to and show concern of others\u2019 emotional states, indicating dispositional empathic orientation. This tendency is tested in a peer context, involving emotions of positive and negative valence. In addition, we assess the infants\u2019 early communicative and prosocial behaviours in the emotionally charged situation. This will reveal the early developmental phases of the fundamental base for intersubjectivity. In the second part of the research, the evolution intersubjectivity is tested by assessing empathy in non-human primates. According to the recent cooperative breeding hypothesis, humans evolved as cooperative breeders, which increased sensitivity and motivation to attend to and show concern of others\u2019 emotional states. The hypothesis is tested by assessing rudimentary empathy in common marmosets, a distantly related cooperatively breeding monkey. To allow full comparability, we will use identical methods in the infant and the marmoset studies. The study incorporates theoretical backgrounds and methods from several disciplines, i.e., comparative cognition, animal behaviour, developmental psychology, evolutionary anthropology, and sociological interaction research. The multidisciplinary approach yields understanding of the emotional and cognitive foundation of intersubjective interactions no single discipline can achieve alone. Moreover, the study yields fruitful prospects for future research lines in the respective disciplines and their synthesis.", "To": ["2017-09-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["653957"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Investigation of shape evolution in neutron-rich nuclei using gamma-ray spectroscopy techniques"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["Shape Evolution"], "Technology_Description": "In the past 100 years, various theoretical approaches have been proposed to model the complex strong interaction between the neutrons and protons in a nucleus, however, a thorough understanding of its quantum structure is still far from being complete. Studies of the evolution of nuclear structure in mass regions away from the valley of stability have revealed dramatic modifications of the ordering of single-particle orbitals in exotic nuclei as compared to the ones predicted by the Shell Model. These surprising results have prompted the need for a detailed study of exotic nuclear systems in order to identify the driving forces behind them. The experimental study of these highly unstable exotic nuclear systems is extremely challenging and have become possible only recently due to the advent of radioactive ion beam facilities and highly efficient detection systems.", "To": ["2018-10-02, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2016-10-03"], "Project_ID": ["702590"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "CENTRO DE INVESTIGACIONES ENERGETICAS, MEDIOAMBIENTALES Y TECNOLOGICAS-CIEMAT", "NARODOWE CENTRUM BADAN JADROWYCH"], "EU_Contribution": ["EUR 4 653 523,88"], "Project_Title": ["QUAdrupoleCOrrector"], "Total_Cost": ["EUR 6 647 891,25"], "Country": ["Switzerland", "France", "Spain", "Poland"], "Project_ACR": ["Quaco"], "Technology_Description": "The full exploitation of the Large Hadron Collider (LHC) is the highest priority of the European Strategy for particle physics. Because of this accelerator Europe is in a leading global position on High Energy Physics research. To preserve that position, the LHC will need a major upgrade in the 2020s to increase its luminosity by a factor of five beyond its design value. The novel configuration, known as High Luminosity LHC, is based on the development of key innovative technologies representing exceptional technological challenges.", "To": ["2020-02-29, ongoing project |"], "Meta": [""], "Topic_s": ["INFRASUPP-2-2015 - Innovative procurement pilot action in the field of scientific instrumentation"], "Funding_scheme": ["COFUND-PCP - COFUND (PCP)"], "Coordinated_in": ["Switzerland"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations"], "From": ["2016-03-01"], "Project_ID": ["689359"], "Call_for_Proposal": ["H2020-INFRASUPP-2015-2"]}, -{"Partners": ["COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Broadband Superconducting Nanowire Single Photon Detectors"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["SuSiPOD"], "Technology_Description": "Single-photon detection is an emerging technology, with applications ranging from medical imaging and LIDAR systems to space communication and fundamental quantum optics. Moreover, single-photon detectors are considered an enabling technology for the development of quantum information science, paving the way for the realization of one of the main challenges of the 21st century: the quantum computer. Currently, single-photon detection is carried out using semiconductor-based avalanche photodiodes; however, this technology is limited by large timing jitter, unavoidable dark counts, after pulsing, and limited detection efficiency. A recently proposed alternative relies on a superconducting nanowire biased just below its critical current, so that an impinging photon triggers a transition from the superconducting to the normal state, resulting in a voltage spike at the nanowire leads. The detection efficiency can be boosted close to unity by coupling the superconducting nanowire to the evanescent field propagating in a waveguide. However, the fabrication of high quality, ultra-thin superconducting layers is challenging, and the operation wavelength of such devices is limited by the waveguide band gap. We have identified GaN/AlN as the best suited waveguide material system, approximately lattice matched with NbN, and with a transparent band from 400 to 6000 nm. The target of the SuSiPOD project is the establishment of a technology platform for the fabrication of a new generation of broadband superconducting nanowire single-photon detectors built on III-nitride waveguides, in which photons are coupled laterally with the help of a tapered optical fibre. This new geometry should allow near-unity absorption probability in a wide spectral range, since the substrate is transparent to visible and infrared light. The project success will be proven by the realization of a working prototype which will greatly outperform state-of-the-art single-photon detectors.", "To": ["2017-06-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2015-07-01"], "Project_ID": ["657497"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "STOCKHOLMS UNIVERSITET"], "EU_Contribution": ["EUR 1 495 476"], "Project_Title": ["Emergent spacetime and maximally spinning black holes"], "Total_Cost": ["EUR 1 495 476"], "Country": ["France", "France", "Sweden"], "Project_ACR": ["Emergent-BH"], "Technology_Description": "One of the greatest challenges of theoretical physics is to understand the fundamental nature of gravity and how it is reconciled with quantum mechanics. Black holes indicate that gravity is holographic, i.e. it is emergent, together with some of the spacetime dimensions, from a lower-dimensional field theory. The emergence mechanism has just started to be understood in certain special contexts, such as AdS/CFT. However, very little is known about it for the spacetime backgrounds relevant to the real world, due mainly to our lack of knowledge of the underlying field theories.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["679278"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["OFFICE NATIONAL D'ETUDES ET DE RECHERCHES AEROSPATIALES", "OFFICE NATIONAL D'ETUDES ET DE RECHERCHES AEROSPATIALES"], "EU_Contribution": ["EUR 1 377 290"], "Project_Title": ["AEROelastic instabilities and control of FLEXible Structures"], "Total_Cost": ["EUR 1 377 290"], "Country": ["France", "France"], "Project_ACR": ["AEROFLEX"], "Technology_Description": "Aeroelastic instabilities are at the origin of large deformations of structures and are limiting the capacities of products in various industrial branches such as aeronautics, marine industry, or wind electricity production. If suppressing aeroelastic instabilities is an ultimate goal, a paradigm shift in the technological development is to take advantage of these instabilities to achieve others objectives, as reducing the drag of these flexible structures. The ground-breaking challenges addressed in this project are to design fundamentally new theoretical methodologies for (i) describing mathematically aeroelastic instabilities, (ii) suppressing them and (iii) using them to reduce mean drag of structures at a low energetic cost. To that aim, two types of aeroelastic phenomena will be specifically studied: the flutter, which arises as a result of an unstable coupling instability between two stable dynamics, that of the structures and that the flow, and vortex-induced vibrations which appear when the fluid dynamics is unstable. An aeroelastic global stability analysis will be first developed and applied to problems of increasing complexity, starting from two-dimensional free-vibrating rigid structures and progressing towards three-dimensional free-deforming elastic structures. The control of these aeroelastic instabilities will be then addressed with two different objectives: their suppression or their use for flow control. A theoretical passive control methodology will be established for suppressing linear aeroelastic instabilities, and extended to high Reynolds number flows and experimental configurations. New perturbation methods for solving strongly nonlinear problems and adjoint-based control algorithm will allow to use these aeroelastic instabilities for drag reduction. This project will allow innovative control solutions to emerge, not only in flutter or vortex-induced vibrations problems, but also in a much broader class of fluid-structure problems.", "To": ["2020-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2015-07-01"], "Project_ID": ["638307"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Mapping an uncertain future: Social and spatial change in conflicting Syria"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["FUTURESYRIA"], "Technology_Description": "This research project in Human Geography aims at understanding the spatial and social dynamics of the Syrian conflict (from 2011 onwards). It focuses particularly on the local dimension of both the dynamics of the uprising, the political mobilisations, and the militarisation of the conflict, as well as on the different types of local networks and local organisations and forms of governance that developed since. Looking at the dynamics of the current crisis \u2018from the ground\u2019 helps indeed our understanding of the current spatial and social reorganisations.", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["658133"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 999 805,42"], "Project_Title": ["Dynamic Nuclear Polarization at ultra-fast sample spinning and ultra-low temperature"], "Total_Cost": ["EUR 1 999 805,42"], "Country": ["France", "France", "France"], "Project_ACR": ["ULT-MAS-DNP"], "Technology_Description": "The goal of the project is to develop a new hyperpolarization approach called Magic Angle Spinning Dynamic Nuclear Polarization (MAS-DNP) to reach levels of sensitivity and resolution that have never been achieved, in order to tackle highly relevant chemical and biological questions that remain unanswered so far. Firstly this will provide major advances in NMR crystallography (solving 3D structures by NMR) by showing that distance measurements between nuclei (13C, 15N, etc.) as well as 17O quadrupolar parameters can be extracted from NMR measurements without requiring isotopic labeling. This will be applied to systems that cannot be easily isotopically enriched and for which X-ray analysis is often not suitable. Secondly we propose an innovative strategy to hyperpolarize nuclear spins using MAS-DNP: rather than polarizing the entire system uniformly, we will selectively \u201clight up\u201d regions where we wish to gather important structural information. This will be developed to study protein-ligand interactions (with unprecedented resolution) to answer specific structural questions and potentially impact the field of drug engineering. Finally we will show that the unique experimental setup developed in this project will open up NMR to the routine study of \u201cexotic\u201d, yet ubiquitous and highly informative, nuclei such as 43Ca and 67Zn. Specifically, we will show that MAS-DNP can become a choice technique for the study of diamagnetic metal binding sites, complementing EPR for the study of metalloproteins. These goals will be achieved thanks to the development of original methods and advanced instrumentation, allowing sustainable access to low temperatures (down to 10-20 K) and fast pneumatic sample spinning, under microwave irradiation. We expect to improve the current sensitivity to such an extent that 4 orders of magnitude of experimental timesavings are obtained, resulting in completely new research directions and regimes.", "To": ["2021-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations"], "From": ["2016-07-01"], "Project_ID": ["682895"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Interpreting Dust Polarization Maps to Characterize the Role of the Magnetic Field in Star Formation Processes"], "Total_Cost": ["EUR 1 500 000"], "Country": ["France", "France"], "Project_ACR": ["MagneticYSOs"], "Technology_Description": "\"Rotation and angular momentum transport play a critical role in the formation and evolution of astrophysical objects, including the fundamental bricks of astrophysical structures: stars. Stars like our Sun form when rotating dense cores, in the interstellar medium, collapse until they eventually reach temperatures at which nuclear fusion begins; while planets, including the Earth, form in the rotationally supported disks around these same young stars. One of the major challenges of modern astrophysics is the \u201cangular momentum problem\"\": observations show that a typical star-forming cloud needs to reduce its specific angular momentum by 5 to 10 orders of magnitude to form a typical star such as our Sun. It is also crucial to solve the angular momentum problem to understand the formation of protoplanetary disks, stellar binaries and the initial mass function of newly formed stars. Magnetic fields are one of the key ways of transporting angular momentum in astrophysical structures: understanding how angular momentum is transported to allow star formation requires characterizing the role of magnetic fields in shaping the dynamics of star-forming structures. The MagneticYSOs project aims at characterizing the role of magnetic field in the earliest stage of star formation, during the main accretion phase.", "To": ["2021-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2016-07-01"], "Project_ID": ["679937"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["ERNST-MORITZ-ARNDT-UNIVERSIT\u00c4T GREIFSWALD", "ERNST-MORITZ-ARNDT-UNIVERSIT\u00c4T GREIFSWALD", "UNIVERSITATSMEDIZIN GREIFSWALD KORPERSCHAFT DES OFFENTLICHEN RECHTS"], "EU_Contribution": ["EUR 1 491 250"], "Project_Title": ["Nanomethods to understand what makes an endogenous protein immunogenic"], "Total_Cost": ["EUR 1 491 250"], "Country": ["Germany", "Germany", "Germany"], "Project_ACR": ["PredicTOOL"], "Technology_Description": "One of the major challenges in understanding the complex immune system is the question when and why this defense system attacks endogenous proteins (i.e. self-proteins). Currently, there are no reliable methods to predict what induces such an immune response, despite it has a major impact in medicine by causing autoimmune diseases, and in biotechnology by inducing adverse reactions towards new drugs.", "To": ["2020-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-04-01"], "Project_ID": ["637877"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Electron quantum optics in Graphene"], "Total_Cost": ["EUR 1 500 000"], "Country": ["France", "France"], "Project_ACR": ["COHEGRAPH"], "Technology_Description": "Quantum computing is based on the manipulation of quantum bits (qubits) to enhance the efficiency of information processing. In solid-state systems, two approaches have been explored: ", "To": ["2021-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2016-05-01"], "Project_ID": ["679531"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 476 000"], "Project_Title": ["Spin-orbit mechanism in adaptive magnetization-reversal techniques, for magnetic memory design"], "Total_Cost": ["EUR 1 476 000"], "Country": ["France", "France"], "Project_ACR": ["SMART DESIGN"], "Technology_Description": "Compared to existing Random Access Memories, the Magnetic RAM (MRAM) has the advantage of being non-volatile. Though the basic requirements for reading and writing a single memory element are fulfilled, the present approach based on Spin Transfer Torque (STT) suffers from an innate lack of flexibility. ", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2015-10-01"], "Project_ID": ["638656"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["KUNGLIGA TEKNISKA HOEGSKOLAN", "KUNGLIGA TEKNISKA HOEGSKOLAN"], "EU_Contribution": ["EUR 1 498 729"], "Project_Title": ["Bottom-up hybrid control and planning synthesis with application to multi-robot multi-human coordination"], "Total_Cost": ["EUR 1 498 729"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["BUCOPHSYS"], "Technology_Description": "Current control applications necessitate the treatment of systems with multiple interconnected components, rather than the traditional single component paradigm that has been studied extensively. The individual subsystems may need to fulfil different and possibly conflicting specifications in a real-time manner. At the same time, they may need to fulfill coupled constraints that are defined as relations between their states. Towards this end, the need for methods for decentralized control at the continuous level and planning at the task level becomes apparent. We aim here towards unification of these two complementary approaches. Existing solutions rely on a top down centralized approach. We instead consider here a decentralized, bottom-up solution to the problem. The approach relies on three layers of interaction. In the first layer, agents aim at coordinating in order to fulfil their coupled constraints with limited communication exchange of their state information and design of appropriate feedback controllers; in the second layer, agents coordinate in order to mutually satisfy their discrete tasks through exchange of the corresponding plans in the form of automata; in the third and most challenging layer, the communication exchange for coordination now includes both continuous state and discrete plan/abstraction information. The results will be demonstrated in a scenario involving multiple (possibly human) users and multiple robots.", "To": ["2020-02-29, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-03-01"], "Project_ID": ["639365"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES"], "EU_Contribution": ["EUR 1 839 633,77"], "Project_Title": ["Stars: dynamical Processes driving tidal Interactions, Rotation and Evolution"], "Total_Cost": ["EUR 1 839 633,77"], "Country": ["France", "France"], "Project_ACR": ["SPIRE"], "Technology_Description": "The rotational dynamics of stars strongly impacts their evolution and those of their planetary and galactic environment. Space helio- and asteroseismology recently allowed an observational revolution in this domain. They revealed, e.g., that the core of the Sun is close to a uniform rotation while those of subgiant and red giant stars slow down drastically during their evolution. These important results demonstrate that powerful dynamical mechanisms (internal waves, magnetic fields, turbulence) are in action to extract angular momentum all along the evolution of stars.", "To": ["2020-08-31, ongoing project |"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2015-09-01"], "Project_ID": ["647383"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES"], "EU_Contribution": ["EUR 1 497 411"], "Project_Title": ["non-LinEar sigNal processing for solving data challenges in Astrophysics"], "Total_Cost": ["EUR 1 497 411"], "Country": ["France", "France"], "Project_ACR": ["LENA"], "Technology_Description": "Astrophysics has arrived to a turning point where the scientific exploitation of data requires overcoming challenging analysis issues, which mandates the development of advanced signal processing methods. In this context, sparsity and sparse signal representations have played a prominent role in astrophysics. Indeed, thanks to sparsity, an extremely clean full-sky map of the Cosmic Microwave Background (CMB) has been derived from the Planck data [Bobin14], a European space mission that observes the sky in the microwave wavelengths. This led to a noticeable breakthrough: we showed that the large-scale statistical studies of the CMB can be performed without having to mask the galactic centre anymore thanks to the achieved high quality component separation [Rassat14]. ", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2016-09-01"], "Project_ID": ["678282"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["CHALMERS TEKNISKA HOEGSKOLA AB", "CONSIGLIO NAZIONALE DELLE RICERCHE", "RIJKSUNIVERSITEIT GRONINGEN", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "UNIVERSITAET BASEL", "THE UNIVERSITY OF MANCHESTER", "FUNDACIO INSTITUT CATALA DE NANOCIENCIA I NANOTECNOLOGIA", "UNIVERSITE CATHOLIQUE DE LOUVAIN", "UNIVERSITAET REGENSBURG", "RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "AIXTRON LIMITED", "GESELLSCHAFT FUR ANGEWANDTE MIKRO UND OPTOELEKTRONIK MIT BESCHRANKTERHAFTUNG AMO GMBH", "ALCATEL-LUCENT DEUTSCHLAND AG", "AALTO-KORKEAKOULUSAATIO", "POLITECNICO DI MILANO", "UNIVERSITE DES SCIENCES ET TECHNOLOGIES DE LILLE - LILLE I", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "THALES SA", "UNIVERSITAT AUTONOMA DE BARCELONA", "DANMARKS TEKNISKE UNIVERSITET", "NOKIA OYJ", "STMICROELECTRONICS SRL", "Teknologian tutkimuskeskus VTT Oy", "VARTA MICRO INNOVATION GMBH", "GRAPHENEA SA", "UNIVERSITE DE STRASBOURG", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS", "AVANZARE INNOVACION TECNOLOGICA SL", "TECHNISCHE UNIVERSITAT HAMBURG-HARBURG", "POLITECNICO DI TORINO", "ALBERT-LUDWIGS-UNIVERSITAET FREIBURG", "AIRBUS OPERATIONS SL", "TECHNOLOGICAL EDUCATIONAL INSTITUTE OF CRETE", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA", "CENTRO DE INVESTIGACION COOPERATIVADE ENERGIAS ALTERNATIVAS FUNDACION", "REPSOL SA", "SABANCI UNIVERSITESI", "UMEA UNIVERSITET", "FONDAZIONE BRUNO KESSLER", "TECHNISCHE UNIVERSITAET DRESDEN", "STICHTING KATHOLIEKE UNIVERSITEIT", "THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN", "LINKOPINGS UNIVERSITET", "UNIVERSITAT ZURICH", "TECHNISCHE UNIVERSITAET CHEMNITZ", "FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG", "INSTYTUT TECHNOLOGII MATERIALOW ELEKTRONICZNYCH", "UNIVERSITA DEGLI STUDI DI TRIESTE", "UNIVERSITAET BREMEN", "UNIVERSIDAD DE CASTILLA - LA MANCHA", "KAROLINSKA INSTITUTET", "EIDGENOSSISCHE MATERIALPRUFUNGS- UND FORSCHUNGSANSTALT", "UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN", "UNIVERSITE DE GENEVE", "TECHNISCHE UNIVERSITEIT DELFT", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "NPL MANAGEMENT LIMITED", "OXFORD INSTRUMENTS NANOTECHNOLOGY TOOLS LIMITED", "LANCASTER UNIVERSITY", "UNIVERSITAET HAMBURG", "NOKIA R&D (UK) LIMITED", "STIFTELSEN CHALMERS INDUSTRITEKNIK", "GRUPO ANTOLIN-INGENIERIA SA", "FUNDACIO INSTITUT DE CIENCIES FOTONIQUES", "TECHNISCHE UNIVERSITAET WIEN", "Asociacion - Centro de Investigacion Cooperativa en Nanociencias - CIC NANOGUNE", "UNIVERSIDADE DO MINHO", "PANEPISTIMIO IOANNINON", "CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL", "TECHNISCHE UNIVERSITAET MUENCHEN", "FUNDACION IMDEA NANOCIENCIA", "FONDATION EUROPEENNE DE LA SCIENCE", "SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI DI TRIESTE", "UNIVERSITE DE MONTPELLIER", "UNIVERSIDAD DE ZARAGOZA", "LABORATOIRE NATIONAL DE METROLOGIE ET D'ESSAIS", "HORIBA FRANCE SAS", "UNIVERSITE DE NAMUR ASBL", "KARLSRUHER INSTITUT FUER TECHNOLOGIE", "FRIEDRICH-SCHILLER-UNIVERSITAT JENA", "PIXIUM VISION", "UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6", "CENTRO DE INVESTIGACION BIOMEDICA EN RED", "GUGER TECHNOLOGIES OG", "CONSORCI INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER", "UNIVERSITAET BIELEFELD", "UNIVERSITAET ULM", "BASF SE", "CNM TECHNOLOGIES GMBH", "FUNDACION TECNALIA RESEARCH & INNOVATION", "POLYMEM", "UNIVERSITY COLLEGE LONDON", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "AMALYST LIMITED", "UNIVERSITA DEGLI STUDI DI PADOVA", "UNIWERSYTET WARSZAWSKI", "BRETON SPA", "TECHNISCHE UNIVERSITEIT EINDHOVEN", "DSM Ahead BV", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA", "USTAV FYZIKALNI CHEMIE J. HEYROVSKEHO AV CR, v. v. i.", "G24 POWER LIMITED", "ITALCEMENTI FABBRICHE RIUNITE CEMENTO SPA", "ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA", "TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY", "ATHERM", "UNIVERSITE LIBRE DE BRUXELLES", "SELEX ES SPA", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.", "EPCOS AG", "THE UNIVERSITY OF NOTTINGHAM", "THE UNIVERSITY OF SHEFFIELD", "ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOMATERIALES- CIC biomaGUNE", "UNIVERSITA DI PISA", "ISTITUTO NAZIONALE DI FISICA NUCLEARE", "MAGYAR TUDOMANYOS AKADEMIA ENERGIATUDOMANYI KUTATOKOZPONT", "PANEPISTIMIO KRITIS", "Institute of Mechanics, Bulgarian Academy of Sciences", "BELARUSIAN STATE UNIVERSITY", "UNIVERSITA DEGLI STUDI DI SALERNO", "ITA-SUOMEN YLIOPISTO", "RESEARCH AND DEVELOPMENT OF NANOMATERIALS AND NANOTECHNOLOGY NANO TECHLAB LTD", "QUEEN MARY UNIVERSITY OF LONDON", "PROGNOMICS LTD", "INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM", "ERICSSON AB", "CONSORZIO NAZIONALE INTERUNIVERSITARIO PER LE TELECOMUNICAZIONI", "LIBRE SOCIETA A RESPONSABILITA LIMITATA", "GRINP SRL", "DYESOL ITALIA SRL", "TARTU ULIKOOL", "N VISION SYSTEMS AND TECHNOLOGIES SL", "UNIVERSITAET AUGSBURG", "UNIVERSITY OF SUNDERLAND", "CENTRO RICERCHE FIAT SCPA", "INSTITUTO DE TECNOLOGIAS EMERGENTES DE LA RIOJA", "NANESA SRL", "DELTA TECH SPA", "ABB AB", "INTERNACIONAL DE COMPOSITES SA", "ALCATEL-LUCENT ITALIA S.P.A.", "FUNDACION PARA LA INVESTIGACION, DESARROLLO Y APLICACION DE MATERIALES COMPUESTOS", "FLEXENABLE LIMITED", "INFINEON TECHNOLOGIES AG", "M-SOLV LTD", "NANOSC AB", "NOVALIA LIMITED", "GLAXOSMITHKLINE RESEARCH AND DEVELOPMENT LTD", "LEONARDO - SOCIETA PER AZIONI", "INSTITUT FUR KORROSIONSSCHUTZ DRESDEN GMBH", "ROBERT BOSCH GMBH", "EMBERION OY", "Emberion Ltd", "NOKIA SOLUTIONS AND NETWORKS UK LIMITED"], "EU_Contribution": ["EUR 89 000 000"], "Project_Title": ["Graphene-based disruptive technologies"], "Total_Cost": ["EUR 89 000 000,10"], "Country": ["Sweden", "Italy", "Netherlands", "Spain", "Switzerland", "United Kingdom", "Spain", "Belgium", "Germany", "Germany", "France", "United Kingdom", "Germany", "Germany", "Finland", "Italy", "France", "France", "France", "Spain", "Denmark", "Finland", "Italy", "Finland", "Austria", "Spain", "France", "United Kingdom", "Germany", "Greece", "Spain", "Germany", "Italy", "Germany", "Spain", "Greece", "United Kingdom", "Italy", "Spain", "Spain", "Turkey", "Sweden", "Italy", "Germany", "Netherlands", "Ireland", "Sweden", "Switzerland", "Germany", "Germany", "Poland", "Italy", "Germany", "Spain", "Sweden", "Switzerland", "Ireland", "Switzerland", "Netherlands", "Switzerland", "United Kingdom", "United Kingdom", "United Kingdom", "Germany", "United Kingdom", "Sweden", "Spain", "Spain", "Austria", "Spain", "Portugal", "Greece", "Germany", "Germany", "Spain", "France", "Italy", "France", "Spain", "France", "France", "Belgium", "Germany", "Germany", "France", "France", "Spain", "Austria", "Spain", "Germany", "Germany", "Germany", "Germany", "Spain", "France", "United Kingdom", "United Kingdom", "United Kingdom", "Italy", "Poland", "Italy", "Netherlands", "Netherlands", "Switzerland", "Italy", "Czech Republic", "United Kingdom", "Italy", "Italy", "Israel", "France", "Belgium", "Italy", "Germany", "Germany", "United Kingdom", "United Kingdom", "Spain", "Italy", "Italy", "Hungary", "Greece", "Bulgaria", "Belarus", "Italy", "Finland", "Bulgaria", "United Kingdom", "United Kingdom", "Belgium", "Sweden", "Italy", "Italy", "Italy", "Italy", "Estonia", "Spain", "Germany", "United Kingdom", "Italy", "Spain", "Italy", "Italy", "Sweden", "Spain", "Italy", "Spain", "United Kingdom", "Germany", "United Kingdom", "Sweden", "United Kingdom", "United Kingdom", "Italy", "Germany", "Germany", "Finland", "United Kingdom", "United Kingdom"], "Project_ACR": ["GrapheneCore1"], "Technology_Description": "This project is the second in the series of EC-financed parts of the Graphene Flagship. The Graphene Flagship is a 10 year research and innovation endeavour with a total project cost of 1,000,000,000 euros, funded jointly by the European Commission and member states and associated countries. The first part of the Flagship was a 30-month Collaborative Project, Coordination and Support Action (CP-CSA) under the 7th framework program (2013-2016), while this and the following parts are implemented as Core Projects under the Horizon 2020 framework.", "To": ["2018-03-31, ongoing project"], "Meta": [""], "Topic_s": ["FETFLAGSHIP - FETFLAGSHIP"], "Funding_scheme": ["SGA-RIA - SGA-RIA"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Chiara Andreoli", "Tel.: +3901071781854", "Fax: +39 010 7170817", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Other", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-04-01"], "Project_ID": ["696656"], "Call_for_Proposal": ["H2020-Adhoc-2014-20"]}, -{"Partners": ["KATHOLIEKE UNIVERSITEIT LEUVEN", "KATHOLIEKE UNIVERSITEIT LEUVEN", "UNIVERSITY OF LEEDS"], "EU_Contribution": ["EUR 2 605 897"], "Project_Title": ["Astrochemistry of old stars:direct probing of unique chemical laboratories"], "Total_Cost": ["EUR 2 605 897"], "Country": ["Belgium", "Belgium", "United Kingdom"], "Project_ACR": ["AEROSOL"], "Technology_Description": "The gas and dust in the interstellar medium (ISM) drive the chemical evolution of galaxies, the formation of stars and planets, and the synthesis of complex prebiotic molecules. The prime birth places for this interstellar material are the winds of evolved (super)giant stars. These winds are unique chemical laboratories, in which a large variety of gas and dust species radially expand away from the star.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["646758"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["HEINRICH-HEINE-UNIVERSITAET DUESSELDORF", "HEINRICH-HEINE-UNIVERSITAET DUESSELDORF"], "EU_Contribution": ["EUR 2 393 447,50"], "Project_Title": ["Early Microbial Evolution"], "Total_Cost": ["EUR 2 393 447,50"], "Country": ["Germany", "Germany"], "Project_ACR": ["eMicrobevol"], "Technology_Description": "From the primordial emergence of the earliest cells to the ongoing diversification of modern microbiota, the mechanisms that underlie the origin of major prokaryotic groups are still poorly understood. In principle, the origin of both species and higher taxa among prokaryotes should entail similar mechanisms \u2014 ecological interactions with the environment paired with natural genetic variation involving lineage-specific gene innovations and lineage-specific gene acquisitions. Because eukaryotes started out as a prokaryote lineage, the same holds true at the prokaryote-eukaryote transition. Prokaryotic higher taxa are currently circumscribed by phylogenomic studies encompassing 30-40 proteins for information processing that are universal to all genomes, or nearly so. The core is useful in taxonomy but comprises only about 1% of an average genome. It does not predict gene content in the remaining 99% of the genome, because of the role of lateral gene transfer (LGT) in generating diversity within and between prokaryotic groups. Especially in groups with large pangenomes or broad ecological diversity, the core itself does not reveal which gene innovations underlie the origin of major groups, but gene distributions might. This proposal aims to harness all the evolutionary data that genomes have to offer \u2014 gene trees, gene distributions, and split distributions across sets of trees \u2014 to chart the history of the 99% component of microbial genome evolution and the role of LGT in the origin of higher microbial taxa. The focus is on three important questions: i) What are the quantitative and lineage specific relative contributions of gene transfer from endosymbionts vs. gene transfers from other prokaryotes during eukaryotic genome evolution, ii) Are there significant differences in verticality in comparisons of genome evolution in prokaryotes vs. eukaryotes and how can we statistically better quantify them, and iii) What was the biological nature of the earliest prokaryotes.", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-11-01"], "Project_ID": ["666053"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["UNIVERSITE PARIS DIDEROT - PARIS 7", "UNIVERSITE PARIS DIDEROT - PARIS 7"], "EU_Contribution": ["EUR 1 589 000"], "Project_Title": ["Magnetic approaches for Tissue Mechanics and Engineering"], "Total_Cost": ["EUR 1 589 000"], "Country": ["France", "France"], "Project_ACR": ["MaTissE"], "Technology_Description": "\"While magnetic nanomaterials are increasingly used as clinical agents for imaging and therapy, their use as a tool for tissue engineering opens up challenging perspectives that have rarely been explored. Lying at the interface between biophysics and nanomedicine, and based on magnetic techniques, the proposed project aims to magnetically design functional tissues and to explore the tissular fate of nanomaterials. Magnetic nanoparticles will be safely introduced into therapeutic cells, thus allowing them to be remotely manipulated by external magnets. 3D manipulations of the magnetized cells (patented in 2012) will be used to form tissues with a controlled size and shape through the development of a unique magnetic bioreactor. In a self-integrating all-in-one process, 3D tissue will be shaped from cellular \"bricks\" without the need for a scaffold. The magnetic tissue will be amenable to mechanical stimulation and in situ imaging at each step of its maturation. The project is inherently multidisciplinary:", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-07-01"], "Project_ID": ["648779"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Probing quantum fluctuations of single electronic channels in model interacting systems"], "Total_Cost": ["EUR 1 500 000"], "Country": ["France", "France"], "Project_ACR": ["NSECPROBE"], "Technology_Description": "The fluctuation-dissipation theorem is a prominent milestone in Physics: It links the dissipative response of a physical system to its fluctuations, and provides a microscopic understanding of macroscopic irreversibility. Recent theoretical advances that have generalized the original fluctuation-dissipation theorem to non-linear quantum systems even far from equilibrium, ask for an experimental test, which is the aim of the project. We will measure the current fluctuations and dissipative response of driven quantum systems whose non-linearity arises from strong interactions. We will exploit the flexibility offered by nano-patterned high purity 2D electron gases in order to realize single electron channels in different regimes: 1/ interacting strongly with a single electromagnetic mode (Dynamical Coulomb Blockade of a quantum point contact), 2/ interacting with a single magnetic impurity (Kondo effect in quantum dots), 3/ driving the 2D gas in the fractional quantum Hall effect where current is carried by strongly correlated 1D channels prototypical of Luttinger liquids. Last, we will address a fundamental issue raised in the early days of quantum mechanics: how long does it take for a particle to cross a classically forbidden barrier? While Wigner-Smith\u2019s theorem links the issue to the density fluctuations within the barrier, the fluctuation-dissipation theorem links it further to a quantum relaxation resistance. A full investigation of fluctuation-dissipation relations including quantum effects requires measurements at frequencies hf>k_BT. With the available dilution refrigeration techniques it implies measuring in the few GHz range. Since quantum conductors have an impedance h/e^2~25.8 kohm much larger than the 50ohm impedance of microwave components, new microwave methods able to deal with large impedance values will be developed. They will be based on the extension to finite magnetic field of the wide-band impedance matching methods recently developed by the PI.", "To": ["2020-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2015-05-01"], "Project_ID": ["639039"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES"], "EU_Contribution": ["EUR 2 499 746,66"], "Project_Title": ["The cerebral representation of sequences and roles : investigating the origins of human uniqueness."], "Total_Cost": ["EUR 2 499 746,66"], "Country": ["France", "France"], "Project_ACR": ["NeuroSyntax"], "Technology_Description": "What are the origins of humans\u2019 remarkable capacities to grasp, memorize, and produce complex sequences and rules, as manifested in language and mathematics? During its evolution, the human brain may have acquired a capacity to represent nested rules, based in part on the expansion of circuits involving the inferior frontal gyrus. This hypothesis will be tested using behavioral measures, functional MRI, magneto-encephalography (MEG), electro-corticography (ECOG) and machine learning techniques in human and non-human primates tested in identical paradigms. ", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2016-10-01"], "Project_ID": ["695403"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Production and decay of Hypernuclei by using an intense heavy-ion beam incidenting on a Proton target"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["ProHyPro"], "Technology_Description": "A new hypernuclei program based on the exclusive measurement of (p, \u039bK) reactions in inverse kinematics is proposed. The program is to be held at the heavy-ion beam facility GSI, Germany. GSI is the only facility worldwide where this measurement can be performed. It is considered as a first step towards a world-unique program dedicated to the population and spectroscopy of exotic hypernuclei at the future FAIR facility.", "To": ["2018-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2016-06-01"], "Project_ID": ["705023"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES"], "EU_Contribution": ["EUR 2 500 000"], "Project_Title": ["CMOS/magnetoelectronic Integrated Circuits wil Multifunctional Capabilities"], "Total_Cost": ["EUR 2 500 000"], "Country": ["France", "France"], "Project_ACR": ["MAGICAL"], "Technology_Description": "Spin Transfer Torque Magnetic memories (STT-MRAM) are receiving a growing R&D effort within the microelectronic industry aiming at the replacement of DRAM or SRAM at sub-20nm nodes. ", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2015-11-01"], "Project_ID": ["669204"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES"], "EU_Contribution": ["EUR 2 554 923,90"], "Project_Title": ["Neural mechanisms of learning in the infant brain : from Statistics to Rules and Symbols"], "Total_Cost": ["EUR 2 554 923,90"], "Country": ["France", "France"], "Project_ACR": ["Babylearn"], "Technology_Description": "Infant is the most powerful learner: He learns in a few months to master language, complex social interactions, etc. Powerful statistical algorithms, simultaneously acting at the different levels of functional hierarchies have been proposed to explain learning. I propose here that two other elements are crucial. The first is the particular human cerebral architecture that constrains statistical computations. The second is the human\u2019s ability to access a rich symbolic system. I have planned 6 work packages using the complementary information offered by non-invasive brain-imaging techniques (EEG, MRI and optical topography) to understand the neural bases of infant statistical computations and symbolic competence from 6 months of gestation up until the end of the first year of life.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2016-09-01"], "Project_ID": ["695710"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES"], "EU_Contribution": ["EUR 2 098 157,50"], "Project_Title": ["The Hall Plateau Transition and non-unitary Quantum Field Theory"], "Total_Cost": ["EUR 2 098 157,50"], "Country": ["France", "France"], "Project_ACR": ["NuQFT"], "Technology_Description": "I propose to solve the Quantum Field Theory (QFT) describing the transition between plateaus of quantized Hall conductance in the Integer Quantum Hall Effect (IQHE). ", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2015-10-01"], "Project_ID": ["669205"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["UNIVERSITEIT LEIDEN", "UNIVERSITEIT LEIDEN"], "EU_Contribution": ["EUR 1 807 334"], "Project_Title": ["Moralising Misfortune: A comparative anthropology of commercial insurance"], "Total_Cost": ["EUR 1 807 334"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["MoralisingMisfortune"], "Technology_Description": "This is a study of the morality of commercial life insurance. What moral issues are raised when commercial companies define responsibilities for misfortune and the appropriateness of entitlements? What are the concerns about the financialization of life and intimacy?", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["682467"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Structural studies of mammalian Cys-loop receptors"], "Total_Cost": ["EUR 1 500 000"], "Country": ["France", "France"], "Project_ACR": ["PentaBrain"], "Technology_Description": "In the brain, Cys-loop receptors mediate fast neurotransmission. They function as allosteric signal transducers across the plasma membrane: upon binding of one or more neurotransmitter molecules to an extracellular site, the receptors undergo complex conformational transitions that result in transient opening of an intrinsic ion channel. The Cys-loop family comprises receptors activated by serotonin, acetylcholine, glycine and GABA. Mammalian receptors are also the targets of a legion of psycho-active and therapeutic compounds (including nicotine, benzodiazepines, anti-emetics, general anaesthetics). Our structural knowledge is currently limited to invertebrate homologues. Atomic structures mammalian receptors are therefore acutely missing in order to understand their physiological role in molecular terms, and to be able to develop new drugs targeting them. ", "To": ["2020-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2015-06-01"], "Project_ID": ["637733"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES"], "EU_Contribution": ["EUR 264 668,40"], "Project_Title": ["Large scale structure of the Universe and fundamental physics"], "Total_Cost": ["EUR 264 668,40"], "Country": ["France"], "Project_ACR": ["NLO-CO"], "Technology_Description": "The purpose of this cosmology project is to study the content and evolution of our Universe using the distribution of matter on large scales. A key goal of forthcoming galaxy surveys is probing fundamental physics, such as the mass of neutrinos and the nature of dark energy, the component sourcing cosmic acceleration. The analysis and interpretation of their data crucially relies on the development of perturbation theory methods and other theoretical tools to describe and predict the evolution of large scale structures in the universe, particularly in the non-linear regime. This project aims to establish the optimal approach to compute the growth of structures and to extract information about dark energy and neutrino masses from the data.", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2017-11-01"], "Project_ID": ["706434"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["POLITECHNIKA SLASKA", "UNIVERSITY OF STRATHCLYDE", "KAUNO TECHNOLOGIJOS UNIVERSITETAS", "POLITECHNIKA LODZKA", "UNIVERSITY OF DURHAM", "CENTITVC - CENTRO DE NANOTECNOLOGIA E MATERIAIS TECNICOS FUNCIONAIS E INTELIGENTES ASSOCIACAO", "OSSILA LIMITED", "AIXTRON SE", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 3 717 198,72"], "Project_Title": ["Donor-Acceptor light emitting exciplexes as materials for easily to tailor ultra-efficient OLED lighting"], "Total_Cost": ["EUR 3 717 198,72"], "Country": ["Poland", "United Kingdom", "Lithuania", "Poland", "United Kingdom", "Portugal", "United Kingdom", "Germany", "France"], "Project_ACR": ["EXCILIGHT"], "Technology_Description": "Artificial lighting is a global and growing industry. New forms of efficient solid state lighting (SSL) in particular are rapidly gaining a market share. New OLED technologies (Organic Light Emitting Diode) can revolutionise this industry as they have done in displays because of their potential flexible structure, infinite tailoring of their properties, efficiency and high colour quality. Industrial forecasts predict that the OLED lighting market will grow from $200 million in 2015 to $1.7 billion by 2020. In order to fully benefit from this huge market potential, Europe`s academia and industry are eager to develop new technologies and recruit highly qualified staff. ", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Poland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations"], "From": ["2015-09-01"], "Project_ID": ["674990"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["CENTRE TECNOLOGIC DE TELECOMUNICACIONS DE CATALUNYA", "UNIVERSITA DEGLI STUDI DI PADOVA", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "ATHONET SRL", "UNIVERSITY OF STRATHCLYDE", "WORLDSENSING SL", "HUAWEI TECHNOLOGIES OY (FINLAND) CO LTD", "TOSHIBA RESEARCH EUROPE LIMITED"], "EU_Contribution": ["EUR 3 653 723,88"], "Project_Title": ["Sustainable CellulAr networks harVEstiNG ambient Energy"], "Total_Cost": ["EUR 3 653 723,88"], "Country": ["Spain", "Italy", "United Kingdom", "France", "Italy", "United Kingdom", "Spain", "Finland", "United Kingdom"], "Project_ACR": ["SCAVENGE"], "Technology_Description": "Energy sustainability is key to future mobile networks due to their foreseen capacity upsurge. The objective of the ETN SCAVENGE (Sustainable CellulAr networks harVEstiNG ambient Energy) is to create a training network for early-stage", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-02-01"], "Project_ID": ["675891"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["OSLO UNIVERSITETSSYKEHUS HF", "SORIN CRM SAS", "UNIVERSITAT POLITECNICA DE VALENCIA", "TECHNISCHE UNIVERSITAET DRESDEN", "OVESCO ENDOSCOPY AG", "NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU", "VALOTEC", "FUNDACION PARA LA INVESTIGACION DEL HOSPITAL UNIVERSITARIO LA FE DE LA COMUNIDAD VALENCIANA"], "EU_Contribution": ["EUR 3 957 045,03"], "Project_Title": ["Wireless In-Body Environment"], "Total_Cost": ["EUR 3 957 045,03"], "Country": ["Norway", "France", "Spain", "Germany", "Germany", "Norway", "France", "Spain"], "Project_ACR": ["WiBEC"], "Technology_Description": "WiBEC (Wireless In-Body Environment Communications) is an Innovative Training Network for 16 young researchers, who will be recruited and trained in coordinated manner by Academia, Industry, and Medical Centres. This training will address the Social, Health, and Technology challenges of the H2020:Wireless In-Body Devices. WiBEC\u2019s main objective is to provide high quality and innovative doctoral training to develop the wireless technologies for novel implantable devices that will contribute to the improvement in quality and efficacy of healthcare. Two devices will be used as a focus for the individual researcher\u2019s projects; cardiovascular implants and ingestible capsules to investigate gastro intestinal problems. These devices will enable medical professionals to have timely clinical information at the point of care. The medical motivation is to increase survival rates and improvement of health outcomes with easy and fast diagnosis and treatment. The goal for homecare services is to improve quality of life and independence for patients by enabling ambient assisted living (AAL) at home. In this particular ETN, inter-sectoral and multi-discipline work is essential, as the topic requires cooperation between medical and engineering institutions and industry. This aspect is fulfilled with the participation of two reference hospitals, two medical device manufacturers and three top ranked universities in Europe, covering complementary aspects of the in-body wireless device field. Concerning future employment perspectives; surgery and medical assistance is rapidly becoming more technological than it is today, and a large number of experts combining engineering and medical skills will be required in Europe to enable novel paradigms like AAL to be realised. The ESRs who join this ETN will acquire diverse skills that will enable them to occupy privileged positions to join and promote EU leadership in ICT for Health.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations"], "From": ["2016-01-01"], "Project_ID": ["675353"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES"], "EU_Contribution": ["EUR 1 318 145"], "Project_Title": ["Charge orders, Magnetism and Pairings in High Temperature Superconductors"], "Total_Cost": ["EUR 1 318 145"], "Country": ["France", "France"], "Project_ACR": ["CHAMPAGNE"], "Technology_Description": "For nearly thirty years, the search for a room-temperature superconductor has focused on exotic materials known as cuprates, obtained by doping a parent Mott insulator, and which can carry currents without losing energy as heat at temperatures up to 164 Kelvin. Conventionally three main players were identified as being crucial i) the Mott insulating phase, ii) the anti-ferromagnetic order and iii) the superconducting (SC) phase. Recently a body of experimental probes suggested the presence of a fourth forgotten player, charge ordering-, as a direct competitor for superconductivity. In this project we propose that the relationship between charge ordering and superconductivity is more intimate than previously thought and is protected by an emerging SU(2) symmetry relating the two. The beauty of our theory resides in that it can be encapsulated in one simple and universal \u201cgap equation\u201d, which in contrast to strong coupling approaches used up to now, can easily be connected to experiments. In the first part of this work, we will refine the theoretical model in order to shape it for comparison with experiments and consistently test the SU(2) symmetry. In the second part of the work, we will search for the experimental signatures of our theory through a back and forth interaction with experimental groups. We expect our theory to generate new insights and experimental developments, and to lead to a major breakthrough if it correctly explains the origin of anomalous superconductivity in these materials.", "To": ["2021-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2016-08-01"], "Project_ID": ["694651"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["UNIVERSITY OF CYPRUS", "ENVIRONMENTAL INSTITUTE s.r.o.", "KWR WATER B.V.", "THE AGRICULTURAL RESEARCH ORGANISATION OF ISRAEL - THE VOLCANI CENTRE", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "ADVENTECH - ADVANCED ENVIRONMENTAL TECHNOLOGIES LDA", "UNIVERSIDADE CATOLICA PORTUGUESA", "TECHNISCHE UNIVERSITAET DRESDEN", "UNIVERSITA DEGLI STUDI DI SALERNO", "TECHNISCHE UNIVERSITAET WIEN"], "EU_Contribution": ["EUR 3 708 689,76"], "Project_Title": ["ANtibioticS and mobile resistance elements in WastEwater Reuse applications: risks and innovative solutions"], "Total_Cost": ["EUR 3 708 689,76"], "Country": ["Cyprus", "Slovakia", "Netherlands", "Israel", "Spain", "Portugal", "Portugal", "Germany", "Italy", "Austria"], "Project_ACR": ["ANSWER"], "Technology_Description": "In response to the increasing problem of water shortage, the reuse of treated urban wastewater is considered the most suitable and reliable alternative for sustainable water management and agricultural development. In spite of the benefits associated with this practice, major concerns currently exist, related to the adverse effects regarding chemical and biological contaminants of emerging concern such as antibiotics and mobile antibiotic resistance elements such as antibiotic resistant bacteria and resistance genes. These are now considered as a serious public health problem by various international organizations and the European Commission, because of their spread in the environment, the food chain, drinking water, etc. To tackle these problems, scientists with an interdisciplinary research/training background are urgently needed. This ETN will train a new generation of ESRs to address the risks associated with such contaminants and wastewater reuse. Innovative chemical, microbiological, toxicological and modelling tools, and novel process engineering will form the scientific and training core of their innovative research projects and training. The project will contribute to understanding the fate and transmission of antibiotics and resistance from wastewater to the environment and humans, through soil, ground/surface water and crops. Relevant ELVs will be determined, essential for the development and implementation of regulatory frameworks. This project directly tackles these aspects, by bringing together a multidisciplinary research team, with the private sector, and policy makers and through communication activities towards stakeholders and the wider public.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Cyprus"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["675530"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["REGION HOVEDSTADEN", "REGION HOVEDSTADEN"], "EU_Contribution": ["EUR 2 072 000"], "Project_Title": ["Molecular imaging and targeted therapy of the aggressive phenotype: development of uPAR theranostics for cancer patients"], "Total_Cost": ["EUR 2 072 000"], "Country": ["Denmark", "Denmark"], "Project_ACR": ["uPET"], "Technology_Description": "For practice of personalized medicine in cancer, non-invasive tools for diagnosing at the molecular level are needed. Molecular imaging methods are capable of this while at the same time circumventing sampling error as the whole tumor burden is evaluated.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Denmark"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-10-01"], "Project_ID": ["670261"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["SEAGATE SYSTEMS UK LIMITED", "ALLINEA SOFTWARE LIMITED", "BULL SAS", "UNITED KINGDOM ATOMIC ENERGY AUTHORITY", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "DEUTSCHES FORSCHUNGSZENTRUM FUR KUNSTLICHE INTELLIGENZ GMBH", "DIAMOND LIGHT SOURCE LIMITED", "FORSCHUNGSZENTRUM JULICH GMBH", "KUNGLIGA TEKNISKA HOEGSKOLAN", "SCIENCE AND TECHNOLOGY FACILITIES COUNCIL"], "EU_Contribution": ["EUR 7 882 531"], "Project_Title": ["SAGE"], "Total_Cost": ["EUR 7 882 531,25"], "Country": ["United Kingdom", "United Kingdom", "France", "United Kingdom", "France", "Germany", "United Kingdom", "Germany", "Sweden", "United Kingdom"], "Project_ACR": ["SAGE"], "Technology_Description": "Worldwide data volumes are exploding and islands of storage remote from compute will not scale. We will demonstrate the first instance of intelligent data storage, uniting data processing and storage as two sides of the same rich computational model. This will enable sophisticated, intention-aware data processing to be integrated within a storage systems infrastructure, combined with the potential for Exabyte scale deployment in future generations of extreme scale HPC systems.", "To": ["2018-08-31, ongoing project |"], "Meta": [""], "Topic_s": ["FETHPC-1-2014 - HPC Core Technologies, Programming Environments and Algorithms for Extreme Parallelism and Extreme Data Applications"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["United Kingdom"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2015-09-01"], "Project_ID": ["671500"], "Call_for_Proposal": ["H2020-FETHPC-2014"]}, -{"Partners": ["COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS", "SAFRAN ELECTRONICS & DEFENSE", "UNIVERSITY COLLEGE LONDON", "TECHNISCHE UNIVERSITAET BERLIN"], "EU_Contribution": ["EUR 2 702 397,50"], "Project_Title": ["Data Learning on Manifolds and Future Challenges"], "Total_Cost": ["EUR 2 702 397,50"], "Country": ["France", "Greece", "France", "United Kingdom", "Germany"], "Project_ACR": ["DEDALE"], "Technology_Description": "\"Future data processing challenges in science will enter the \"Big Data\" era, involving massive, as well as complex and heterogeneous data. Extracting, with high precision, every bit of information from scientific data requires overcoming fundamental statistical challenges, which mandate the design of dedicated methods that must be both effective enough to capture the intricacy of real-world datasets and robust to the high complexity of instrumental measurements. Moreover, future datasets, such as those provided by the space mission Euclid, will involve at least gigascale data, which will make mandatory the development of new, physically relevant, data models and the implementation of effective and computationally efficient processing tools. The recent emergence of novel data analysis methods in machine learning should foster a new modeling framework, allowing for a better preservation of the intrinsic physical properties of real data that generally live on intricate spaces, such as signal manifolds. Furthermore, advances in operations research and optimization theory pave the way for effective solutions to overcome the large-scale data processing bottlenecks. In this context, the objective of the DEDALE project is threefold: i) introduce new models and methods to analyze and restore complex, multivariate, manifold-based signals; ii) exploit the current knowledge in optimization and operations research to build efficient numerical data processing algorithms in the large-scale settings; and iii) show the reliability of the proposed data modeling and analysis technologies to tackle Scientific Big Data challenges in two different applications: one in cosmology, to map the dark matter mass map of the universe, and one in remote sensing to increase the capabilities of automatic airborne imaging analysis systems.\"", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-1-2014 - FET-Open research projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["665044"], "Call_for_Proposal": ["H2020-FETOPEN-2014-2015-RIA"]}, -{"Partners": ["UNIVERSITA DEL SALENTO", "UNIVERSITA DEL SALENTO"], "EU_Contribution": ["EUR 1 488 750"], "Project_Title": ["Distributed Optimization Methods for Smart Cyber-Physical Networks"], "Total_Cost": ["EUR 1 488 750"], "Country": ["Italy", "Italy"], "Project_ACR": ["OPT4SMART"], "Technology_Description": "The combination of embedded electronics and communication capability in almost any mobile or portable device has turned this century into the age of cyber-physical networks. Smart communicating devices with their sensing, computing and control capabilities promise to make our cities, transportation systems, factories and living environments more intelligent, energy-efficient, safe and secure. This extremely complex system has raised a number of new challenges involving ICT disciplines. In particular, a novel peer-to-peer distributed computational model is appearing as a new opportunity in which a service is built-up cooperatively by peers, rather than by a unique provider that knows and owns all data. The interdisciplinary \u201cOptimization Community\u201d is facing this revolution sharing a common need: to find new theories, methodologies and tools to optimize over this complex network system. With this in mind, OPT4SMART has a twofold objective. First, to provide a comprehensive theoretical framework to solve distributed optimization problems over peer-to-peer networks. Second, to develop effective numerical tools, based on this framework, to solve estimation, learning, decision and control problems in cyber-physical networks. To achieve this twofold objective, we will take a systems-theory perspective. Specific problems from these four areas will be abstracted to a common mathematical set-up, and addressed by means of interdisciplinary methodologies arising from a synergic combination of optimization, controls, and graph theories. In particular, OPT4SMART will face the challenge of solving optimization problems under severe communication limitations, very-large-scale problem and data size, and real-time computational constraints. The expected result will be a combination of strong theoretical methods and effective numerical toolboxes available to people in Engineering, Computer Science, Mathematics and other areas, who are facing optimization in cyber-physical networks.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["638992"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 2 250 000"], "Project_Title": ["CONTROLLING AND MEASURING RELATIVISTIC MOTION OF MATTER WITH ULTRAINTENSE STRUCTURED LIGHT"], "Total_Cost": ["EUR 2 250 000"], "Country": ["France", "France", "France"], "Project_ACR": ["ExCoMet"], "Technology_Description": "Femtosecond lasers can now provide intensities such that the light field induces relativistic motion of large ensembles of electrons. The ultimate goal of this Ultra-High Intensity (UHI) Physics is the control of relativistic motion of matter with light, which requires a deep understanding of this extreme regime of laser-matter interaction. Such a control holds the promise of major scientific and societal applications, by providing ultra-compact laser-driven particle accelerators and attosecond X-ray sources. Until now, advances in UHI Physics have relied on a quest for the highest laser intensities, pursued by focusing optimally-compressed laser pulses to their diffraction limit. In contrast, the goal of the ExCoMet project is to establish a new paradigm, by demonstrating the potential of driving UHI laser plasma-interactions with sophisticated structured laser beams\u2013i.e. beams whose amplitude, phase or polarization are shaped in space-time.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations"], "From": ["2016-10-01"], "Project_ID": ["694596"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["STICHTING VU", "STICHTING VU", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Extracting Super-Resolution from Classical Fluorescence Microscopy"], "Total_Cost": ["EUR 150 000"], "Country": ["Netherlands", "Netherlands", "France"], "Project_ACR": ["SUPER-RESOL"], "Technology_Description": "The beginning of this century has seen the development of optical super-resolution fluorescence microscopic methods, which yield pictures to resolutions of a few tens of nanometers. This breakthrough has transformed the field of cellular biology, but relies on approaches generally demanding in terms of optics, and which can be applied only on limited classes of fluorophores. This project aims at preparing the commercialization of a new, simple, and cheap, way of extracting super-resolution from images obtained with classical confocal fluorescence microscopes. Currently, this approach yields images with a resolution between 80 nm to 50 nm, which can most likely be increased in a near future. This method can thus be used with any type of fluorophore, just by equipping (confocal) microscopes with a high-end X-Y table and a 2D detector. More complex super-resolution fluorescence microscopic techniques have generated more than 7000 citations in the last years, mostly in biology, but also in chemistry and material sciences. The proposed technology, which can i) easily be implemented for a limited cost and ii) requires no more maintenance and alignment than classical confocal microscopy, is expected to be rapidly implemented in a very large number of laboratories, thus generating new knowledge and a vast range of scientific advances. In the frame of this project, which is a direct consequence of the work started in the frame of the PhotProt ERC advanced grant (id n\u00b0 267333), we will in parallel i) improve the performances of this technology by modifying its present design, ii) perform the necessary patenting of this technology, iii) start market studies to evaluate its actual commercial potential iv) enter in contact with companies devoted to microscope engineering and development, and with detector manufacturers, to raise their interest, and envision under which form this new technology can be commercialized, how to conceive the corresponding commercial prototype.", "To": ["2016-05-31, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2014 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2014-12-01"], "Project_ID": ["640982"], "Call_for_Proposal": ["ERC-2014-PoC"]}, -{"Partners": ["COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES"], "EU_Contribution": ["EUR 1 299 958,26"], "Project_Title": ["Strategic Predictions for Quantum Field Theories"], "Total_Cost": ["EUR 1 299 958,26"], "Country": ["France", "France"], "Project_ACR": ["preQFT"], "Technology_Description": "Ambitious Questions:", "To": ["2020-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2015-06-01"], "Project_ID": ["639729"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["MAGYAR TUDOMANYOS AKADEMIA TARSADALOMTUDOMANYI KUTATOKOZPONT", "MAGYAR TUDOMANYOS AKADEMIA TARSADALOMTUDOMANYI KUTATOKOZPONT"], "EU_Contribution": ["EUR 1 973 500"], "Project_Title": ["No Sword Bites So Fiercly as an Evil Tongue?Gossip Wrecks Reputation, but Enhances Cooperation"], "Total_Cost": ["EUR 1 973 500"], "Country": ["Hungary", "Hungary"], "Project_ACR": ["EVILTONGUE"], "Technology_Description": "Social norms in general, and norms of cooperation in particular, are the cement of all human societies. For the difficult problems of the maintenance and enforcement of social norms and of cooperation, humans have developed surprisingly complex solutions. Reputation mechanisms and gossip are certainly among the compound informal solutions.", "To": ["2020-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Hungary"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2015-12-01"], "Project_ID": ["648693"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["BANGOR UNIVERSITY"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Microbial communities of Temperate, Artic and Tropical peatlands and their role in the response of carbon storage function to global change"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["MicroPEAT"], "Technology_Description": "The present proposal aim at understanding microbial role in peatland sensitivity to climate change at a Global Scale. Peatlands represent one of the most important terrestrial carbon pools, despite they only cover 3% of the earth\u2019s surface they store one third of all terrestrial carbon. This ecosystem has shown to be sensitive to different disturbances in terms of their carbon storage capacity and it is expected a huge CO2 and CH4 release as well as an increase in dissolved organic carbon exportation to freshwater systems, due to climate change. Peatlands cover large extensions in arctic and temperate zones, but they are also present in tropical regions were their ecology and functioning is almost unknown. Due to the valuable peatland role as carbon sink there has been many intents to find out the effect of global change on their functioning, however we are still far to totally comprehend and predict this effect, existing important unsolved questions on the role of microbial decomposer communities (Fungi, Bacteria and Archaea), the structure-function relationship, and so far, none study has assessed the climate change impact at global scale. In order to fill these gaps I propose to survey the microbial communities in Arctic, Temperate and Tropical peatlands and test how differences in origin-legacy can drive peatlands sensitivity to drought events. The proposed methodology is an interdisciplinary approach (combining molecular thechniques, ecosystem measurements and biogeochemistry) with three big components: 1) initial field work study to systematically assess microbial communities from the 3 regions; 2) a microcosm experiment to test the effect of drought (water table reduction) on peatland functioning; 3) a secondment in a drinking water company to put into a management context the results, as these companies are interested in the by-product formation problem thanks to the DOC enhancing in water supplies due to the loss of peatlands storage capacity.", "To": ["2018-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["706616"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Dark energy, non-linearites and effective theories"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["DEFT"], "Technology_Description": "The objective of this project is improving substantially our understanding of the acceleration of the Universe by developing novel effective techniques and semi-analytical methods for non-linear cosmological perturbation theory that will be applied to the data of upcoming high precision surveys. The accelerated expansion of the Universe was first detected in 1998 with Type Ia supernova data, and today there is ample evidence for it from various other observations such as the cosmic microwave background radiation (CMB) and the distribution of galaxies at large scales. We call dark energy the mysterious force that drives the acceleration of the Universe and understanding its origin is one of the major problems in cosmology of our time. The high precision of the near-future probes designed for elucidating the nature of dark energy needs to be matched with very accurate theoretical predictions, in particular concerning non-linear effects in cosmological perturbation theory. Developing efficient methods to compute these effects is a crucial requirement for the interpretation of the future dark energy data. I will apply the methods of effective field theories, that have been widely successful in many areas of physics, to develop new tools for describing dark matter and dark energy perturbations in the linear and non-linear regimes. I will combine these tools with state-of-the-art forecasting techniques to determine the prospects for the detection of dark energy parameters from future large scale structure data (specifically from Euclid) in combination with CMB data from Planck.", "To": ["2017-09-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2015-10-01"], "Project_ID": ["656794"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES"], "EU_Contribution": ["EUR 149 913"], "Project_Title": ["SolarPredict: An advanced predictive tool and service of the Solar 11-yr Activity Cycle"], "Total_Cost": ["EUR 149 913"], "Country": ["France", "France"], "Project_ACR": ["SolarPredict"], "Technology_Description": "The main idea of the SolarPredict Proof of Concept project is to use physically based dynamo models to make solar 11-yr activity predictions, in particular of Earth impacting events, more robust/reliable and to develop the tools to make them accessible (with the appropriate licencing and IPR) to customers (such as private corporations or governmental agencies) as a service, software or paid/freemium applications. The key advantage of our tools/techniques over current ones is both our deep knowledge of the working of the solar dynamo and magnetism and the implementation in solar physics of state-of-the-art variational data assimilation (DA) techniques used daily in weather forecasting. These variational techniques are known to be more robust and versatile than for instance sequential methods or simple geomagnetic precursors thus allowing us to incorporate the highly complex solar magnetic activity and dynamics into our forecasting tools. Thanks to our advanced 2-D direct and adjoint mean field dynamo codes and modern DA technique, we will assimilate the most relevant solar observational data (sunspots numbers, polar cap magnetic field, surface flows...) into our prediction model hence allowing us to develop an operational prototype. Indeed major solar storms are strongly correlated to the intensity of solar cycle and 80% of them are directly due to the presence of complex active regions that are more frequent as the 11-yr cycle intensifies. Thus being able to anticipate the level and geometry of solar global magnetism give us a competitive edge in predicting major solar storms. We will thus bring with the SolarPredict project, our novel variational DA solar prediction algorithm to a more mature state such as to make it operational and useful to private companies and governmental agencies in order to help them evaluate the economic cost of solar activity and associated storms and protect their assets by anticipating such devastating solar activity.", "To": ["2016-08-31, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2014 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2015-03-01"], "Project_ID": ["640997"], "Call_for_Proposal": ["ERC-2014-PoC"]}, -{"Partners": ["AARHUS UNIVERSITET", "INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM", "STICHTING KATHOLIEKE UNIVERSITEIT", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "QUANTUMWISE A/S"], "EU_Contribution": ["EUR 3 395 178,25"], "Project_Title": ["Spintronic-Photonic Integrated Circuit platform for novel Electronics"], "Total_Cost": ["EUR 3 395 178,25"], "Country": ["Denmark", "Belgium", "Netherlands", "France", "Denmark"], "Project_ACR": ["SPICE"], "Technology_Description": "The main objective of SPICE is to realize a novel integration platform that combines photonic, magnetic and electronic components. Its validity will be shown by a conceptually new spintronic-photonic memory chip demonstrator with 3 orders of magnitude higher write speed and 2 orders of magnitude lower energy consumption than state-of-the-art spintronic memory technologies. This enables, e.g., future petabit-per-second processor-memory bandwidths, required in a decade from now, and highly energy-efficient exascale datacenters with reduced carbon footprint. Such a versatile memory will result in so-called Universal Memory: one technology for all memory applications ranging from cache to storage.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-1-2014 - FET-Open research projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-10-01"], "Project_ID": ["713481"], "Call_for_Proposal": ["H2020-FETOPEN-2014-2015-RIA"]}, -{"Partners": ["ASSOCIACAO DO INSTITUTO SUPERIOR TECNICO PARA A INVESTIGACAO E DESENVOLVIMENTO", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "IMAGINE OPTIC", "UNIVERSIDAD POLITECNICA DE MADRID", "STICHTING CENTRUM VOOR WISKUNDE EN INFORMATICA", "CONSIGLIO NAZIONALE DELLE RICERCHE"], "EU_Contribution": ["EUR 3 996 875"], "Project_Title": ["volumetric medical x-ray imaging at extremely low dose"], "Total_Cost": ["EUR 3 996 875"], "Country": ["Portugal", "France", "France", "France", "Spain", "Netherlands", "Italy"], "Project_ACR": ["VOXEL"], "Technology_Description": "Computerized Tomography (CT) has been one of the greatest achievements in medical imaging, but at the cost of a high, potentially harmful, X-ray irradiation dose. The ultimate goal of VOXEL is to provide an alternative to tomography with a disruptive technology enabling 3D X-ray imaging at very low dose. VOXEL aims at prototyping new cameras that will combine the X-ray penetration and nanometre spatial resolution, easiness to use, afforded by avoiding the rotation of the source or the sample, and extremely low dose for maximum impact on medicine and biology. ", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-1-2014 - FET-Open research projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Portugal"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations"], "From": ["2015-06-01"], "Project_ID": ["665207"], "Call_for_Proposal": ["H2020-FETOPEN-2014-2015-RIA"]}, -{"Partners": ["COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Characterizing properties of the interstellar medium to better understand how stars form in galaxies"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["eGALISM"], "Technology_Description": "The complex interplay between the interstellar medium (ISM) and the stars that it gives birth to is central to studies of galaxy evolution. The properties of the ISM, and especially its capacity to cool, determine when and where star formation occurs. Those properties are well-known in the Milky Way but not in external galaxies. Only recently has the extragalactic community dedicated effort to obtain very rich archives of the ISM tracers (dust, CO and now [CII]) from both space and ground based observatories, but we currently lack a detailed multi-wavelength and multiphase modeling that can exploit the data in a self-consistent way.", "To": ["2019-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2017-02-01"], "Project_ID": ["702622"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES"], "EU_Contribution": ["EUR 261 957,60"], "Project_Title": ["Inter-individual variability in learning: an investigation of its determinants"], "Total_Cost": ["EUR 261 957,60"], "Country": ["France"], "Project_ACR": ["LearningDeterminants"], "Technology_Description": "The ability to extract regularities from the environment (statistical learning) is an essential feature of the primate brain. While inter-individual differences exist in statistical learning capacity in humans, little is know as to their origins. The present project proposes to investigate the cognitive and neural determinants of these differences, and to ask what their impact might be on the acquisition of a foundational skill for education, i.e. reading. ", "To": ["2018-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2015-05-01"], "Project_ID": ["661667"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS", "POLITECNICO DI MILANO", "STICHTING VU", "RUHR-UNIVERSITAET BOCHUM", "TELEFONICA INVESTIGACION Y DESARROLLO SA", "F-SECURE OYJ"], "EU_Contribution": ["EUR 702 000"], "Project_Title": ["Restoring Trust in the cyber space: a Systems Security Proposal"], "Total_Cost": ["EUR 702 000"], "Country": ["Greece", "Italy", "Netherlands", "Germany", "Spain", "Finland"], "Project_ACR": ["PROTASIS"], "Technology_Description": "Fueled by a string of high profile attacks and recent revelations about unprecedented cyber surveillance, interest in systems security is rising-not just among industry and governments, but even among individual citizens across Europe. Corporate organizations worry about the viability of their businesses, nation states about cyber attacks by other nation states or terrorist groups, and citizens about the trustworthiness of the ICT infrastructures. The long list of recent security incidents is eroding people's trust in the digital economy and shows that more research is needed.", "To": ["2020-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Greece"], "Activity": ["Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-05-01"], "Project_ID": ["690972"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["CONSIGLIO NAZIONALE DELLE RICERCHE", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "STIFTUNG DEUTSCHES ELEKTRONEN-SYNCHROTRON DESY", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "INSTALLATION EUROPEENNE DE RAYONNEMENT SYNCHROTRON", "FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS", "FORSCHUNGSZENTRUM JULICH GMBH", "FUNDACIO INSTITUT CATALA DE NANOCIENCIA I NANOTECNOLOGIA", "KARLSRUHER INSTITUT FUER TECHNOLOGIE", "LUNDS UNIVERSITET", "Promoscience srl", "FUNDACIO PRIVADA PARC DE RECERCA UAB", "PAUL SCHERRER INSTITUT", "SCIENCE AND TECHNOLOGY FACILITIES COUNCIL", "TECHNISCHE UNIVERSITAET GRAZ", "TECHNISCHE UNIVERSITAET MUENCHEN", "UNIVERSITA DEGLI STUDI DI MILANO", "UNIVERZA V NOVI GORICI", "UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA"], "EU_Contribution": ["EUR 9 994 861"], "Project_Title": ["NANOSCIENCE FOUNDRIES AND FINE ANALYSIS - EUROPE"], "Total_Cost": ["EUR 11 759 061"], "Country": ["Italy", "France", "France", "Germany", "Switzerland", "France", "Greece", "Germany", "Spain", "Germany", "Sweden", "Italy", "Spain", "Switzerland", "United Kingdom", "Austria", "Germany", "Italy", "Slovenia", "Spain"], "Project_ACR": ["NFFA-Europe"], "Technology_Description": "NFFA-EUROPE will implement the first open-access research infrastructure as a platform supporting comprehensive projects for multidisciplinary research at the nanoscale extending form synthesis to nanocharacterization to theory and numerical simulation. The integration and the extension of scope of existing specialized infrastructures within an excellence network of knowledge and know-how will enable a large number of researchers from diverse disciplines to carry out advanced proposals impacting science and innovation. The full suite of key infrastructures for nanoscience will become, through the NFFA-EUROPE project, accessible to a broader community extended to research actors operating at different levels of the value chain, including SMEs and applied research, that are currently missing the benefits of these enabling technologies. NFFA-EUROPE sets out to offer an integrated, distributed infrastructure to perform comprehensive nanoscience and nanotechnology projects from synthesis and nanolithography (with nanofoundry installations) to advanced characterization and theoretical modellization/numerical simulation (with experimental installations including analytical large scale facilities and a distributed theoretical installation including high-performance computing). Coordinated access will be given to complementary facilities co-located in nine well distributed main sites in Europe, ensuring the optimal match between user proposal and technical offer. The research activity of the Consortium will realize innovative solutions on key bottlenecks of nanoscience research, therefore upgrading the facility quality and uniqueness.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["INFRAIA-1-2014-2015 - Integrating and opening existing national and regional research infrastructures of European interest"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["654360"], "Call_for_Proposal": ["H2020-INFRAIA-2014-2015"]}, -{"Partners": ["COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES"], "EU_Contribution": ["EUR 129 807"], "Project_Title": ["Millimeter Wave Massive Arrays enabling RFID/Radar Applications on 5G Smartphones"], "Total_Cost": ["EUR 129 807"], "Country": ["France"], "Project_ACR": ["MAPS"], "Technology_Description": "Nowadays, a rising interest is moving towards the fifth generation (5G) of wireless mobile communication, as numerous devices and different heterogeneous networks will be interconnected, guaranteeing zero-distance connectivity between people, devices and objects. To deal with the ever increasing data traffic demand and the low power consumption requirements in the perspective of a sustainable growth, smart solutions have to provide energy- and cost-efficient services. In this context, the massive antenna arrays deployment in base stations, access points or smartphones, appears like a viable solution to meet these new challenges. Besides communication, the availability of such a technology can also allow other interesting applications such as accurate simultaneous localization and mapping (SLAM) performed by a personal radar integrated in smartphones, enabling new services in the device-to-device communication. In addition, the interrogation of tagged objects placed in the environment through radiofrequency identification (RFID) technology will allow a mapping of the real world into the internet space, enabling environment-related applications and constitute the so called smart space within the Internet of Things concept. Moreover, the reduced wavelength at millimeter-waves (mmW) paves the way for packing a large number of antenna elements into a small area, overcoming the difficult integration of laser-based or mechanical steering devices into mobiles. ", "To": ["2017-01-19, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2015-07-20"], "Project_ID": ["659067"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK", "INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES"], "EU_Contribution": ["EUR 4 698 623,50"], "Project_Title": ["Access to European Nanoelectronics Network"], "Total_Cost": ["EUR 4 698 623,75"], "Country": ["Ireland", "Belgium", "France"], "Project_ACR": ["ASCENT"], "Technology_Description": "ASCENT will provide access to the world\u2019s most advanced 10 nm and beyond-CMOS nanoelectronics data and test structures in Europe\u2019s leading nanofabrication research institutes. The institutes involved have extensive advanced semiconductor processing fabrication facilities, flexible nanofabrication facilities, advanced electrical characterization equipment and expertise in atomistic and TCAD modeling. This will be the first time that access to these state-of-the-art devices and test structures will be available anywhere in the world. The impact of this access, and the resulting advances that will be made, will contribute significantly to competitiveness and growth capacity in the Europe\u2019s nanoelectronics industry. ", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["INFRAIA-1-2014-2015 - Integrating and opening existing national and regional research infrastructures of European interest"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations"], "From": ["2015-05-01"], "Project_ID": ["654384"], "Call_for_Proposal": ["H2020-INFRAIA-2014-2015"]}, -{"Partners": ["INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT", "CENTRE DE COOPERATION INTERNATIONALE EN RECHERCHE AGRONOMIQUE POUR LEDEVELOPPEMENT - C.I.R.A.D. EPIC", "UNIVERSITE RENNES II", "UNIVERSITAET INNSBRUCK", "STIFTELSEN THE STOCKHOLM ENVIRONMENT INSTITUTE", "LANCASTER UNIVERSITY", "Instituto Superior de Agronomia", "LISODE SARL", "GEOMATYS", "VIEIRA PAK MANUELA", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSITE DE GUYANE", "UNIVERSITE DE MONTPELLIER", "UNIVERSITE PAUL SABATIER TOULOUSE III"], "EU_Contribution": ["EUR 1 705 500"], "Project_Title": ["OBSERVATORY OF THE DYNAMICS OF INTERACTIONS BETWEEN SOCIETIES AND ENVIRONMENT IN THE AMAZON"], "Total_Cost": ["EUR 1 849 500"], "Country": ["France", "France", "France", "Austria", "Sweden", "United Kingdom", "Portugal", "France", "France", "France", "France", "France", "France", "France"], "Project_ACR": ["ODYSSEA"], "Technology_Description": "Achieving a sustainable development trajectory in Amazonia is one of the key challenges facing Brazil, and is also an important international concern. ODYSSEA assembles an internationally renowned European and Brazilian multidisciplinary and intersectoral team. We aim to produce fundamental science and tools in order to build an innovative multi-and interdisciplinary observatory to monitor and assess dynamic interactions between Amazon societies and their environments. This observatory will serve as a basis for policy development that integrates social, environmental, political-economic and human health dimensions. Our methodology puts the society at the heart of the observatory\u2019s building process, engaging stakeholders and decision makers in the research to favour advancement of their objectives and commitment to sustainable development issues.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["691053"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["ACADEMISCH ZIEKENHUIS GRONINGEN", "UNIVERSITY OF KENT", "INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE", "STOCKHOLMS UNIVERSITET", "HUMBOLDT-UNIVERSITAET ZU BERLIN", "ERNST-MORITZ-ARNDT-UNIVERSIT\u00c4T GREIFSWALD", "NOVOZYMES A/S", "DSM FOOD SPECIALTIES BV", "UCB Celltech"], "EU_Contribution": ["EUR 3 685 072,68"], "Project_Title": ["Engineering of new-generation protein secretion systems"], "Total_Cost": ["EUR 3 685 072,68"], "Country": ["Netherlands", "United Kingdom", "France", "Sweden", "Germany", "Germany", "Denmark", "Netherlands", "United Kingdom"], "Project_ACR": ["ProteinFactory"], "Technology_Description": "The market for recombinant proteins, including biopharmaceuticals, industrial enzymes and membrane proteins, is estimated to be about 78 billion Euro and rising. A high proportion of the target proteins are produced in bacteria, where secretion out of the cytoplasm is a favoured strategy. However, current production platforms have severe limitations and cannot handle many secreted enzymes and membrane proteins. There is an overwhelming need for new production systems that can deliver these products in greater yields, with higher quality and at lower costs. The 'ProteinFactory' ETN will meet these challenges through the provision of a suite of super-secreting strains with unique capabilities. These strains will be engineered to bypass major production bottlenecks such as secretion stress, and will be capable of secreting an unprecedented range of target molecules. Equally important will be the training of a new generation of researchers, versed in Systems and Synthetic Biology approaches. The ProteinFactory project will involve extensive collaboration between 6 academic Institutes, who provide world-leading expertise in synthetic biology and protein secretion, and 5 non-academic partners who include some of the world's premier biotechnology companies. Training will be inter-sectoral from the outset, with every ESR undertaking extensive secondments within the non-academic partners in order to encourage an entrepreneurial mind-set. The project is furthermore explicitly multi-disciplinary in scope, with two of the five research work packages dominated by theoretical approaches. Based on a responsible innovation approach and with a clear focus on inter-sectoral collaboration, ProteinFactory will deliver a cohort of superbly-trained scientists, put the industrial and SME partners at the forefront of global competition and reinforce European innovation potentials with growth and job creation.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["642836"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["DUBLIN CITY UNIVERSITY", "THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS", "UNIVERSITEIT GENT", "CENTRO DE ESTUDOS SOCIAIS", "OXFORD BROOKES UNIVERSITY", "FORSCHUNGSSTELLE FUR UNABHANGIGE LITERATUR UND GESELLSCHAFTLICHE BEWEGUNGEN OSTEUROPAS AN DER UNIVERSITAT BREMEN", "TALLINNA TEHNIKAULIKOOL"], "EU_Contribution": ["EUR 3 811 357,08"], "Project_Title": ["Around the Caspian: a Doctoral Training for Future Experts in Development and Cooperation with Focus on the Caspian Region"], "Total_Cost": ["EUR 3 811 357,08"], "Country": ["Ireland", "United Kingdom", "Belgium", "Portugal", "United Kingdom", "Germany", "Estonia"], "Project_ACR": ["CASPIAN"], "Technology_Description": "The main goal of this project is to train the next generation of experts on the Caspian region in order to establish, and make sustainable, a network of excellence. This will be achieved through an integrated PhD programme on the Caspian that boosts the researchers\u2019 theoretical, empirical and administrative skills, a thing that will make them extremely competitive for employment in both academic and non-academic sectors but also confident and knowledgeable enough to start their own projects. The training will enhance the research skills of the ESRs while also giving them a first-hand experience with a partner operating in a different environment, thus learning how to apply their skills to different fields and sectors. We expect our network and training to become a leading voice on issues related to the Caspian region both in academia and other sectors.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2015-01-01"], "Project_ID": ["642709"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET", "UNIVERSITY COLLEGE LONDON", "KAROLINSKA INSTITUTET", "THE ROYAL VETERINARY COLLEGE", "UNIVERSITAIR MEDISCH CENTRUM UTRECHT", "NORDIC BIOSCIENCE COMPOUND DEVELOPMENT A/S", "Gr\u00fcnenthal GmbH"], "EU_Contribution": ["EUR 3 558 676,32"], "Project_Title": ["European Training Network on Bone Pain"], "Total_Cost": ["EUR 3 558 676,32"], "Country": ["Denmark", "United Kingdom", "Sweden", "United Kingdom", "Netherlands", "Denmark", "Germany"], "Project_ACR": ["BonePain"], "Technology_Description": "The aim is to create an innovative European PhD training network in bone pain. Millions in Europe and beyond suffer from bone pain, a debilitating complication of many musculoskeletal disorders such as arthritis and bone metastasis. However, being a truly multidisciplinary subject spanning neuroscience, bone biology, and even cancer research, it demands a multidisciplinary approach. Despite a huge negative impact on the quality of life of the patients and on society as a whole, no specific treatment is available. To address this societal challenge and the strong innovation potential, we want to form the first European platform to promote frontline research, innovation and education within bone pain. The network encompasses 5 academic and 2 industrial beneficiaries and 1 industrial partner all committed to creating an outstanding wide-ranging yet integrated training program for early stages researchers to elucidate the mechanisms of bone pain and develop new medicines. We will use in vivo models of arthritic pain, cancer-induced bone pain and fracture pain to investigate the pathophysiology and novel treatment strategies. In vivo electrophysiology will be used for studying the physiology and pharmacology of pain transmission and its modulation. Transgenic mouse models will be used to tease out the specific neuronal receptor subtypes involved. Sophisticated behaviour tests will evaluate response to novel treatments. We will create a biobank of human cancer-infiltrated bone to identify specific patterns of neuronal receptor expression and to validate therapeutic targets in humans. In an extensive training effort covering both specific research skills and transferable skills, the students will obtain an interdisciplinary, state-of-the-art and innovative training from the participants, several of which have experience from international networks. The students will benefit from secondments with industrial partners and with some of the foremost pain researchers in Europe.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["642720"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["UNIVERSITAT ROVIRA I VIRGILI", "ECOLE POLYTECHNIQUE", "NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "SILVACO EUROPE LTD", "INFINISCALE SA", "ADMOS GMBH ADVANCED MODELING SOLUTIONS", "TECHNISCHE HOCHSCHULE MITTELHESSEN", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 742 500"], "Project_Title": ["Design Oriented ModellINg for flexible electrOnics"], "Total_Cost": ["EUR 742 500"], "Country": ["Spain", "France", "Netherlands", "France", "United Kingdom", "France", "Germany", "Germany", "United Kingdom"], "Project_ACR": ["DOMINO"], "Technology_Description": "Our project aims to fill the gap between flexible electronic technology and design by developing highly predictive, generic, open-source, design-oriented organic and oxide based TFT compact model libraries, to be integrated in commercial Electron Design Automation (EDA) environments for full large area low cost circuit design for novel applications. These model libraries will be released together with parameter extraction standard templates to assist in the fast transfer between initial prototype device measurements to full product design. Such a facility will open the opportunity for wide flexible electronics design", "To": ["2018-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2014-12-01"], "Project_ID": ["645760"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["INSTYTUT BIOLOGII DOSWIADCZALNEJ IM. M. NENCKIEGO POLSKIEJ AKADEMII NAUK"], "EU_Contribution": ["EUR 2 302 080"], "Project_Title": ["International Doctoral Programme in Biological Bases of Human Diseases"], "Total_Cost": ["EUR 4 604 160"], "Country": ["Poland"], "Project_ACR": ["Bio4Med"], "Technology_Description": "The major aim of Bio4Med (Biology for Medicine) programme is to provide unique, international, inter-disciplinary and inter-sectoral doctoral training for Early Stage Researchers (ESRs) in the domain of biological bases of human diseases. To achieve this goal it combines 22 leading research groups at the Nencki Institute and their scientific partners from world-class laboratories located in EU Member States, Switzerland, Ukraine, Japan, Canada and US. Research programme includes basic science PhD-projects focused on molecular basis of neurodegeneration, neurological disorders, cancer and metabolic diseases. All supervising researchers engaged in the Bio4Med are at the international forefront of biomedical research and have experience in PhD student supervision. Our programme will foster young researchers\u2019 career development and employability by addressing the following objectives: (i) to offer excellent training in modern biology and endow ESRs with unique scientific knowledge, and experience in cutting-edge experimental techniques; (ii) to enhance research-oriented and transferable skills of ESRs; (iii) to promote scientific mobility via international, inter-disciplinary and inter-sectoral collaboration. The objectives of Bio4Med will be delivered through activities encompassing practical laboratory training, hands-on workshops, lectures corresponding to the theoretical aspects of doctoral projects, research-oriented generic skills courses, transferrable skills courses, progress talks and meetings. The training programme itself, focused on medically important issues, will make ESRs highly attractive to commercial enterprises, particularly in biotechnology and pharmaceutical sectors. Bio4Med programme will increase the regional, national as well as EU competitiveness by providing a new generation of visionary and innovative researchers able to transform basic science into healthcare solutions.", "To": ["2020-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2014-DP - Marie Sk\u0142odowska-Curie Co-funding of regional, national and international programmes (COFUND-DP)"], "Funding_scheme": ["MSCA-COFUND-DP - Doctoral programmes"], "Coordinated_in": ["Poland"], "Activity": ["Research Organisations"], "From": ["2015-05-01"], "Project_ID": ["665735"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2014"]}, -{"Partners": ["COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES"], "EU_Contribution": ["EUR 149 634"], "Project_Title": ["Universal Pulses for Parallel Transmission and Magnetic Resonance Imaging"], "Total_Cost": ["EUR 149 634"], "Country": ["France", "France"], "Project_ACR": ["UniPAT"], "Technology_Description": "The parallel transmission technology is a promising technique to counteract the radiofrequency (RF) field inhomogeneity problem in Magnetic Resonance Imaging (MRI) at ultra-high field. It consists of placing around the subject several RF transmitters that can be controlled independently in amplitude and phase. By using sophisticated algorithms, it is then possible to design the respective waveforms which lead to a uniform excitation. This powerful tool on the other hand has remained a research instrument mostly due to the calibration and calculation time necessary to exploit the technology in each exam (around 10 minutes), and the required expertise to calculate the waveforms. ", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2015 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2016-09-01"], "Project_ID": ["700812"], "Call_for_Proposal": ["ERC-2015-PoC"]}, -{"Partners": ["UNIVERSITEIT UTRECHT", "ACADEMISCH ZIEKENHUIS LEIDEN", "UNIVERSITAETSKLINIKUM HEIDELBERG", "CARDIFF UNIVERSITY", "UNIVERSITE D'AIX MARSEILLE", "KATHOLIEKE UNIVERSITEIT LEUVEN", "ARATANA THERAPEUTICS NV", "AICURIS GMBH & CO. KG", "COMPLIX NV", "UNIVERSITAT WIEN", "VIROVET", "COMPLIX LUXEMBOURG SA"], "EU_Contribution": ["EUR 3 849 086,91"], "Project_Title": ["European Training Network on Antiviral Drug Development"], "Total_Cost": ["EUR 3 849 086,91"], "Country": ["Netherlands", "Netherlands", "Germany", "United Kingdom", "France", "Belgium", "Belgium", "Germany", "Belgium", "Austria", "Belgium", "Luxembourg"], "Project_ACR": ["ANTIVIRALS"], "Technology_Description": "Viral infections are a major cause of disease, mortality and economic losses worldwide. Antiviral therapy is an essential instrument to control virus infections. At present, however, licensed antiviral drugs have been developed only against a limited number of viruses (e.g. HIV, HCV, influenza, herpesviruses). There is a clear and unmet need for antiviral drugs to treat infections with other important human pathogens.", "To": ["2019-02-28, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-03-01"], "Project_ID": ["642434"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU"], "EU_Contribution": ["EUR 208 400,40"], "Project_Title": ["Taming Irregular Computations On Heterogeneous processors"], "Total_Cost": ["EUR 208 400,40"], "Country": ["Norway"], "Project_ACR": ["TICOH"], "Technology_Description": "In the past decade, more and more heterogeneous processors are equipping modern supercomputers. Unfortunately, despite the progress of hardware infrastructure, the utilization of heterogeneous computing is still relatively low in practice. The utilization mainly suffers from two bottlenecks: distributed memories that bring high cost for software engineering and degraded performance, and lack of heterogeneity-oriented scalable approaches for irregular problems. The objective of the project TICOH is to address the issue of currently unsatisfactory utilization of heterogeneous computing for irregular problems such as graph and sparse matrix processing. Following a multi-level approach which bridges the domains of performance measurement, benchmark data analysis, modeling, data structure construction, algorithm design and application integration, TICOH will explore best practices that toward the best performance for irregular computations on the best hardware selection. Specifically, the main focus of the project will be to (a) identify and understand bottlenecks of current heterogeneous computing, (b) benchmark and model heterogenous processors composed of CPU, GPU and high-bandwidth memories, (c) design and evaluate new data structures and algorithms for irregular problems aiming for fully use computing and memory resources, and (d) integrate and apply the newly designed approaches for high-level applications. By empirically investigating these issues, the ultimate goal of the project is to allow a broad range of real-world applications to further benefit from heterogeneous hardware in the new era. Prof. Anne C. Elster will be hosting this action at the HPC-Lab of NTNU. Her research team is known for its experience with heterogeneous computing, and is one of the main partners in the H2020 CloudLightning project. This environment will guarantee successful bidirectional transfer of knowledge.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["752321"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES"], "EU_Contribution": ["EUR 149 404"], "Project_Title": ["Classical Levitonics: transposing quantum levitons to classical waves for single side band wireless data transmissions"], "Total_Cost": ["EUR 149 404"], "Country": ["France", "France"], "Project_ACR": ["C-Levitonics"], "Technology_Description": "The project addresses the field of wireless digital communication. This field has constantly grown during the last twenty years with the development of cell phones and WiFi Local Area Network and with the development of digital TV broadcasting and satellite communications. A second expansion of digital communications has recently started with networks of objects: Bluetooth smart devices are available to consumers and RFID devices are used for object tagging, security identification and health sensors. Connecting devices will lead in a very near future to the Internet of Things. Digital communications form a huge market of 100 billion of transceivers connecting humans and devices. Any technological improvement is expected to generate important economic benefits. This is the aim of C-Levitonics. To physically encode binary information, wireless, optical fiber or copper wire data transmissions are based on the modulation of the phase or the amplitude of an electromagnetic wave, called carrier wave. A new waveform for the phase modulation associated with an elementary symbol (or bit) is proposed. It derives from a direct application to classical physics of the recently discovered levitons in quantum physics, a by-product of a former ERC AdG MeQuaNO project. The new modulation, called Single Side Band Phase Shift Keying (SSB-PSK), provides attractive spectral properties: single side band (SSB) spectrum (highly desired feature in optical or radio communications) and reduced frequency bandwidth allowing more users in a frequency range. Totally new (patent pending) SSB-PSK can operate using existing digital communication technology. A convincing demonstrator based on software radio technology will be delivered. In parallel a market prospective will identify the best markets and the technical specifications adjusted to them. At the end of the C-Levitonics project a start-up will be created providing development, consulting services and licensed technology transfer.", "To": ["2017-05-31, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2015 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2015-12-01"], "Project_ID": ["680875"], "Call_for_Proposal": ["ERC-2015-PoC"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Understanding sexual selection to help controlling an invasive pest species"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["SexSelec_Invasion"], "Technology_Description": "Invasive species can have dramatic consequences on the receiving ecosystem and on human activities. At the same time, invasion episodes offer a rare opportunity to observe evolution in action and study adaptation. Understanding the cornerstone role of sexual selection during adaptation can open an avenue of strategies to fight against pest species. During invasion, novel environmental conditions and rapid changes in the genetic composition of populations are expected to influence the dynamics of sexual selection. However, neither theory nor data clearly predict whether sexual selection would be reinforced or hampered during an invasive episode. Understanding the subtle consequences of invasion on sexual selection is crucial, as mating strategies provide tools to fight against pest species. The Sterile Insect Technique (SIT) successfully eliminated several pest species, limiting side-effects on the ecosystem compared to traditional techniques such as pesticides. In this project, I develop a series of experiments combining artificial selection experiments with large scale phenotyping to investigate the dynamics of sexual selection during invasion and test the potential to exploit mating strategies to control pest populations in an evolutionary sustainable way. As a model species, I will use Drosophila suzukii, a champion of invasion that colonised several continents and islands in the last decades. Because D. suzukii feeds and oviposits on close-to-be-marketed fruits, it causes considerable economic losses and the situation requires rapid action. The results of the project will provide both a fundamental understanding of the dynamics of sexual selection during invasion, and essential information for the development of sustainable, environment friendly methods to fight pest species, in particular D. suzukii.", "To": ["2020-02-29, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2018-03-01"], "Project_ID": ["752452"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["POLITECHNIKA POZNANSKA", "UNIWERSYTET PRZYRODNICZY W POZNANIU*", "INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK", "UNIWERSYTET IM. ADAMA MICKIEWICZA W POZNANIU", "AKADEMIA WYCHOWANIA FIZYCZNEGO IM EUGENIUSZA PIASECKIEGO", "UNIWERSYTET EKONOMICZNY W POZNANIU"], "EU_Contribution": ["EUR 132 775"], "Project_Title": ["Enthusiasm, Passion, Inspiration, Challenge (EPIC) \u2013 join us during the Researchers\u2019 Night and see for yourself how by connecting science and passion one can make a difference!"], "Total_Cost": ["EUR 139 825"], "Country": ["Poland", "Poland", "Poland", "Poland", "Poland", "Poland"], "Project_ACR": ["EPICNIGHT"], "Technology_Description": "\"Researchers\u2019 Night again in Poznan! EPICNight! Enthusiasm, Passion, Inspiration, Challenge\u2013 join us during the Researchers\u2019 Night and see for yourself how by connecting science and passion one can make a difference! Come and uncover the secrets of scientists and researchers! Open the doors to your good neighbours \u2013 researchers! Measure immeasurable and see invisible! Become a researcher for one night and construct DNA helix, have a ride in 3D helmet, design your own clothes or learn the secrets of Eco-robots! Come and sing karaoke songs with researchers and at the end dress up like a famous scientist and dance with us cha-cha or jive. Feel like doing some sport? These and many other attractions are waiting for you to reveal your passion for science and convince you that researchers are just ordinary people with an extraordinary job and various hobbies!", "To": ["2015-12-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-NIGHT-2014 - European Researchers' Night (NIGHT)"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Poland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2014-05-01"], "Project_ID": ["633236"], "Call_for_Proposal": ["H2020-MSCA-NIGHT-2014"]}, -{"Partners": ["FUNDACAO D. ANNA SOMMER CHAMPALIMAUD E DR. CARLOS MONTEZ CHAMPALIMAUD"], "EU_Contribution": ["EUR 160 635,60"], "Project_Title": ["Phenotypic characterization of Liver-derived exosomes populations associated with liver metastasis in pancreatic cancers"], "Total_Cost": ["EUR 160 635,60"], "Country": ["Portugal"], "Project_ACR": ["ONCOSYSTEMS"], "Technology_Description": "Tumors are not isolated entities, but complex systemic networks involving cell-cell communication between transformed and non-transformed cells. The milieu created by tumor-associated cells may either support or halt tumor progression. Non-tumor cells also play a role at distant sites, preparing future metastatic sites to support engraftment and survival of metastatic cells. In addition to cell-cell contact, cells communicate through secreted factors via a highly complex system involving characteristics such as ligand concentration, receptor expression and integration of diverse signaling pathways. Of these, extracellular vesicles such as exosomes are emerging as novel cell-cell communication players in physiological and pathological scenarios. We recently described that exosomes produced by highly metastatic pancreatic cancers (PC) induce Liver Pre-Metastatic Niches (LPMN) supportive of hepatic metastasis. Although we defined how LPMN are induced by PC-derived exosomes, the specific mechanism of how the LPMN support the formation and progression of liver metastatic lesions is still unknown. In addition, while we have been showing that pre-metastatic niches support metastatic spreading, we still do not have appropriate means to detect the formation of these niches by non-invasive methods in clinical settings. Thus we propose to: 1)Characterize the composition of liver-derived exosomes populations in physiologic and LPMN-associated settings by applying state-of-the-art flow cytometry tailored to nanoparticles analysys at a single-exosome level; 2)Test whether liver-derived exosomes interact with metastatic PC cells and play a role in supporting the progression of PC metastatic lesions in the liver. This project has the potential to offer not only a non-invasive alternative to detect and characterize tumor-associated microenvironments, such as LPMN, but also opportunities for novel therapeutic approaches to target pro-tumorigenic cell-cell communication.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Portugal"], "Activity": ["Research Organisations"], "From": ["2017-07-01"], "Project_ID": ["751547"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KINGSTON UNIVERSITY HIGHER EDUCATION CORPORATION"], "EU_Contribution": ["EUR 146 591,10"], "Project_Title": ["Efficient methods for radiative heat transfer analysis in fires and water sprays for fire suppression"], "Total_Cost": ["EUR 146 591,10"], "Country": ["United Kingdom"], "Project_ACR": ["RAD-FIRE"], "Technology_Description": "The annual cost of losses due to fires is estimated at \u20ac126bn, equivalent to 1% of European global gross domestic product (GDP). The use of performance-based fire safety engineering which relies on fire modeling is seen as a good step to reduce fire losses. Thermal radiation is the most dominant mode of heat transfer in fires and its rigorous and efficient modeling is therefore critical for the reliability of fire safety codes employed in fire engineering. The project aims to improve the current modeling strategies of radiative heat transfer in fires and in fire suppression by water sprays where the interaction between fires and water droplets should be taken into account. Current computational methods used in fire modeling and fire suppression suffer from the main following drawbacks: (1) They use the optically gray Planck mean radiative properties of the composite medium, which are too crude to describe the real spectral behavior of thermal radiation (2) The angular dependence of the radiation intensity is usually approximated with too much details without accounting for the real radiation field; (3) The computational mesh taken from the Computational Fluid Dynamics (CFD) part of the general fire code is too detailed and not appropriate for radiative transfer calculations; (4) the computational requirements for current fire CFD codes are prohibitive and this is an obstacle.", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["749220"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Post-translational modifications during floral initiation: molecular dissection of the UFO-dependent LFY activation"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["PFIMDULA"], "Technology_Description": "Flowering plants are the most successful plant group on Earth and provide the basis for most human and animal food. The development of flowers is dependent on a gene regulatory network orchestrated by LEAFY (LFY), the master transcription factor. In Arabidopsis as in other flowering plants, LFY activity is dependent upon its interaction with UFO, a member of the Skp1\u2013Cullin\u2013F-box E3 ubiquitin ligase complex. The goal of this project is to understand why LFY requires interacting with UFO to build flowers. For this, we will apply state-of-the-art technologies including mass-spectrometry, crystallography, biochemistry and plant developmental genetics to identify and characterize the function of Post-Translational Modifications (PTM) on LFY or LFY interacting proteins, with special emphasis on ubiquitination. After identifying key residues involved in the LFY-UFO interaction or targeted by PTM, their functional importance will be assayed in planta. This project should facilitate better understanding of the mechanism of LFY activation. LEAFY and the development of flower will be used here as a model to understand the \u201cactivation by degradation\u201d mechanism, still elusive in most organisms and poorly studied in plants. Moreover, understanding the principles governing LFY activation should provide means to modify at will the architecture of plant inflorescences. This project builds on the current background of the applicant in the field of Mass-Spectrometry combined with the outstanding expertise at Grenoble and high-throughput facilities in Structural biology and plant developmental genetics. Notably, the applicant will work within one of the top French Research Centers and in a multidisciplinary environment that will allow the fellow to acquire complementary \u2018new knowledge and skills\u2019 in structural biology and developmental genetics. This will re-enforce the fellow\u2019s background and professional maturity for employment opportunities in both academia and industry sectors.", "To": ["2019-06-07, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2017-06-08"], "Project_ID": ["752418"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KING'S COLLEGE LONDON"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Newcomers at the University. Welcome practices and staff involvement in the UK"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["WELCOME-UNIVERSITY"], "Technology_Description": "European universities have significantly changed the way of dealing with newcomers in the last thirty years. As a consequence of the explosion of enrolments, educators, professional staff, and authorities have suddenly been confronted to new categories of students. In addition, the university's governance has experienced rapid changes concerning internationalisation and mobility. The issues that primarily concern researchers and authorities regard the dropout of first-year students (FYS) and the utility of mobility programmes to reinforce a \u201cEuropean identity\u201d. ", "To": ["2019-05-22, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-23"], "Project_ID": ["750444"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FORSCHUNGSZENTRUM JULICH GMBH", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "CINECA CONSORZIO INTERUNIVERSITARIO", "BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION", "GRAND EQUIPEMENT NATIONAL DE CALCUL INTENSIF"], "EU_Contribution": ["EUR 25 967 653,25"], "Project_Title": ["Public Procurement of Innovative Solutions for High-Performance Computing"], "Total_Cost": ["EUR 74 193 295"], "Country": ["Germany", "France", "Italy", "Spain", "France"], "Project_ACR": ["PPI4HPC"], "Technology_Description": "In its communication on the \u201cEuropean Cloud Initiative\u201d the European Commission in April 2016 stressed the need for building an European Data Infrastructure including high-end supercomputers, which will around 2022 reach the exascale performance level. In this proposal, a group of leading European supercomputing centres propose the formation of a buyers group to execute a joint Public Procurement of Innovative Solutions (PPI) in the area of high-performance computing (HPC). The co-funding by the European Commission (EC) will allow for a significant enhancement of the planned pre-exascale HPC infrastructure from 2018 on. The total investment is planned to be about \u20ac 73 million.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["EINFRA-21-2017 - Platform-driven e-infrastructure innovation"], "Funding_scheme": ["PPI - Public Procurement of Innovative solutions"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Other"], "From": ["2017-04-01"], "Project_ID": ["754271"], "Call_for_Proposal": ["H2020-EINFRA-2016-2"]}, -{"Partners": ["UNIWERSYTET IM. ADAMA MICKIEWICZA W POZNANIU"], "EU_Contribution": ["EUR 134 462,40"], "Project_Title": ["Electric field driven propulsion and collective dynamics of homogeneous and patchy colloidal capsules."], "Total_Cost": ["EUR 134 462,40"], "Country": ["Poland"], "Project_ACR": ["PaCDoC"], "Technology_Description": "Colloidal capsules are interesting from the point of view of both physics and application. They can be used for controlled material transport and targeted release, and they have shown tremendous potential for fabricating advanced materials through self-assembly. Recently, such capsules have also been able to propel in carrier fluid by methods including magnetic fields, thermal gradients and bubble propulsion mechanisms. Building on former research by the Experienced Researcher and the main supervisor, as well as new areas of expertise, this project will develop novel fabrication routes for microcapsules with and without functionalised shells (patchy capsules) and propel them over milimeter distances using external fields. The main objective of this action is to experimentally demonstrate propulsion of microcapsules via novel methods involving anisotropic electrodeformation and electrorotation. The experimental research will fill the missing gap in the field of propelling capsules, now mostly presented by computational and theoretical work. ", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Poland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["752896"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI TRENTO"], "EU_Contribution": ["EUR 180 277,20"], "Project_Title": ["Study of the role of m6A RNA methylation in the nervous system of Drosophila melanogaster: an in-vivo model to dissect the impact of epitranscriptome reprogramming in physiology and cancer"], "Total_Cost": ["EUR 180 277,20"], "Country": ["Italy"], "Project_ACR": ["EpiMethFly"], "Technology_Description": "The identification of reversible m6A RNA modification strongly points towards the existence of a novel level of complexity of gene expression regulation. Recent studies have suggested that m6A might be involved in several biological processes and that dysregulation of this modification may contributes to neuro-developmental abnormalities and cancer. The aim of the described research is to clarify the role of m6A RNA modification in the nervous system in physiological conditions -during brain development - and to discover its contribution to pathological conditions - Glioblastoma. To achieve this goal I propose to use Drosophila melanogaster to study : Aim 1 the impact of perturbing different members of the m6A machinery on brain morphology, progenitors differentiation and neuronal axon growth and guidance; Aim2 the impact of modulating the levels of m6A RNA modification in a Glioblastoma model and study the effect of this perturbation on tumor growth and progression. The results obtained will be of fundamental importance for the development of the field of epitranscriptomics by shedding light on the biological outcome of m6A modification in-vivo. In particular, Drosophila might become an efficient model to screen for novel members of the m6A machinery and to clarify how m6A is read and translated into a biological response. Finally, the data obtained by the analysis of the Glioblastoma model, will strongly contribute to the understanding of the link between RNA methylation and tumor development and aggressiveness.", "To": ["2019-09-18, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-19"], "Project_ID": ["752621"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Dolphinfish living in a warming ocean: How global climate change is reshaping the distribution, physiology and behaviour of marine migratory species and their associated fisheries."], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["Co-tRiP"], "Technology_Description": "Ranges of individual fisheries are shifting in response to ocean warning. These shifts can cause economic disruptions if a fish population becomes less or more productive or moves out of traditional fishing grounds. Dolphinfish are known to exhibit strong responses to CC through shifts in spawning areas, larval growth, etc. Dolphinfish inhabit tropical and subtropical waters of the world, including Mediterranean, and it supports commercial, artisanal and recreational fisheries. Balearic Islands, provide a paradigmatic case-study area and fishery scenario for a process-based understanding of how CC may impact migrant species of commercial interest in Europe. Co-tRiP objective is to address ecological socioeconomic consequences of CC on a migrant pelagic fish species under fishing pressure in NW Med. Specific objectives include: 1) To estimate the effect of environmental variability on extension and localization of spawning area, phenology of reproduction and growth of dolphinfish; 2) to address how inter-annual variability of spatial distribution, phenology of reproduction and growth of species, and long-term environmental trends can be used in projecting impacts of CC, such as distribution shifts; 3) to evaluate how projected changes would potentially affect fisheries and anticipate the adjustment of industry. Using a multi-model approach, Co-tRiP will provide more insight into the effect of CC on distribution shift. Co-tRiP will build probabilistic maps, based on distribution models, for spawning area through merging disperses data from multiple sources. Models will be used to back-calculate environmental conditions for spawning in past and present, and project how these will change in future. Data will be used to feed a bio-economical model in order to project how phenological changes may impact fishery, and how it may use this information. Further projections on distribution and phenology will be performed using a suite of ensemble models based on CC scenarios.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["746361"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE DE BORDEAUX"], "EU_Contribution": ["EUR 264 668,40"], "Project_Title": ["A Wearable Sensor for Hormones Based on a Native Microbial Sensing"], "Total_Cost": ["EUR 264 668,40"], "Country": ["France"], "Project_ACR": ["SENSHOR"], "Technology_Description": "Connected devices that monitor human biology in real-time represent the next frontier in biosensors. Monitoring hormones is of significant interest as hormones play critical roles in multiple physiological processes including stress adaptation, blood pressure control, reproductive rhythms, and body odor. However, the real-time monitoring of hormones is challenging from a biology, chemistry, and engineering perspective, insulin detection being the one notable success. This project proposes to design a novel wearable device to sense estradiol (through sweat), a hormone responsible for fertility issues and mood disorders in women. This project is highly innovative and ambitious since it combines microbial genetics and protein identification, new polymer and nanoparticles compositions, and a novel sensor design. The wearable device (i.e., bracelet) will contain an optical-to-electrical interface for recording the fluorescence output of a biosensor, based on estradiol sensitive transcription factor isolated from a microbial organism. The biosensor is composed of biopolymers (dendrimers and polypeptides nanoparticles) functionalized with fluorescent molecular beacons (MB) and a hormone-sensitive transcription factor. Without the hormone, the two fluorescent entities of the MB are linked by the protein and no signal is emitted because of fluorescence resonance energy transfer (FRET), while in the presence of estradiol, the MB separate and a fluorescent signal is emitted. The project will be conducted in two international prestigious laboratories in France and in the USA to give to the applicant the best interdisciplinary scientific environment, and ensure the ultimate success of this project. The applicant will be the main spokesperson and lead investigator of the project. This international exposure and this fellowship will provide the applicant a unique and multidisciplinary profile, while facilitating her future academic career as a researcher in France.", "To": ["2020-03-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-03-15"], "Project_ID": ["749973"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Exploding stars from first principles: MAGnetars as engines of hypernovae and gamma-ray BURSTs"], "Total_Cost": ["EUR 1 500 000"], "Country": ["France", "France"], "Project_ACR": ["MagBURST"], "Technology_Description": "The birth of a neutron star with an extremely strong magnetic field, called a magnetar, has emerged as a promising scenario to power a variety of outstanding explosive events. This includes gamma-ray bursts, among the most luminous events observed up to high redshift and therefore useful as cosmological probes, but also supernovae with extreme kinetic energies called hypernovae and other classes of super-luminous supernovae. Simple phenomenological models, where the magnetar rotation period and magnetic field are adjusted, can explain many of these observations but lack a sound theoretical basis. The goal of this proposal is to develop an ab initio description of magnetar powered explosions in order to delineate the role they play for the production of gamma-ray bursts and super-luminous supernovae. This is urgently needed to interpret the growing diversity of explosions observed with ongoing transient surveys (iPTF, CRTS, Pan-STARRS) and in the perspective of future programs of observations such as SVOM and LSST. By using state-of-the-art numerical simulations, the following outstanding questions will be addressed:", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-05-01"], "Project_ID": ["715368"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["UNIVERSITEIT LEIDEN", "INSTALLATION EUROPEENNE DE RAYONNEMENT SYNCHROTRON", "LEIDEN PROBE MICROSCOPY BV", "TECHNISCHE UNIVERSITAET MUENCHEN", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "PANEPISTIMIO PATRON"], "EU_Contribution": ["EUR 3 726 942,50"], "Project_Title": ["Development of continuous two-dimensional defect-free materials by liquid-metal catalytic routes"], "Total_Cost": ["EUR 3 726 942,50"], "Country": ["Netherlands", "France", "Netherlands", "Germany", "France", "Greece"], "Project_ACR": ["LMCat"], "Technology_Description": "Two-dimensional materials (2DMs) such as graphene, hexagonal boron nitride, silicene and others, are currently amongst the most intensively studied classes of materials that hold great promise for future applications in many technological areas. However, the main hurdle against practical utilization of 2DMs is the lack of effective mass production techniques to satisfy the growing qualitative and quantitative demands for scientific and technological applications. The current state-of-the-art synthesis method of 2DMs involves the dissociative adsorption of gas-phase precursors on a solid catalyst. This process is slow by nature, inefficient, and environmentally unfriendly.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-01-2016-2017 - FET-Open research and innovation actions"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["736299"], "Call_for_Proposal": ["H2020-FETOPEN-1-2016-2017"]}, -{"Partners": ["IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE"], "EU_Contribution": ["EUR 137 155"], "Project_Title": ["Few-Cycle Electric Field Waveforms for Advanced Science and Technology"], "Total_Cost": ["EUR 137 155"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["FEWFAST"], "Technology_Description": "The aim is the development of a user friendly high power few cycle, phase stable, light source in the 1500-2000 nm wavelength range. This builds on technical feasibility demonstrated during the ASTEX Advanced Grant. To fully exploit the potential of this light source it is necessary now to optimize the following characteristics: peak power, the ultimate pulse duration, stability and convenience of use. We hope to do this by building on the work carried out in the ASTEX project, that demonstrated the principle of the generation and application of few cycle waveform stable 1800 nm pulses, by optimising the generation, power and convenience of use to enable many potential applications. It is the aim of this project therefore to develop this light source as a user friendly, stand-alone, optical device that can be located after a variety of commercial ultrafast OPA (Optical Parametric Amplifier) systems and so deliver few cycle 1500-2000 nm high power pulses directly to many and varied applications in technology and science. The applications are expected to have industrial/societal impact in Defence, Security, Analytical and Measurement Technology sectors. ", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["767112"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["TALLINNA TEHNIKAULIKOOL", "UNIVERSITE DE LAUSANNE"], "EU_Contribution": ["EUR 1 318 500"], "Project_Title": ["Institutions for Knowledge Intensive Development: Economic and Regulatory Aspects in South-East Asian Transition Economies"], "Total_Cost": ["EUR 1 318 500"], "Country": ["Estonia", "Switzerland"], "Project_ACR": ["IKID"], "Technology_Description": "The prioritisation and deployment of knowledge within an economy remains a key success factor for long-term economic development, increased productivity and socio-economic sustainability. The achievement of knowledge-driven growth is particularly challenging for emerging market economies that are still seeking to catch up to the frontier knowledge economies. The project seeks to understand the causes and consequences of the differences in the evolution of knowledge intensity of economies, with particular focus on transition countries in South-East Asia. We aim to identify some key micro and macro level institutional incentives for development towards a knowledge economy, and stimuli for capital allocation into knowledge-based investments. Moreover, we seek to study and outline some key channels for efficient regulation that might contribute to knowledge intensification in a transition economy. The project makes use of frontier empirical research methods, including advanced stochastic frontier analysis and dynamic panel data estimation techniques. The conceptual underpinnings of the project are at the intersection of industrial organisation theories, new institutional economics, development economics, and modern concepts in regulatory efficiency and justice. The project will develop lasting excellence oriented cooperation with South-East Asian universities, and contribute to R&D capacity building based on European academic values. Promoting of the project results through intersectoral knowledge transfer will be an important task. We aim to contribute to social innovation through policy suggestions, and to a paradigm shift regarding the role of institutions in transition processes. The project is a joint effort of Swiss and Estonian universities\u2019 economics and law researchers with transition studies experience from Eastern Europe, and their fellow researchers from Laos, Vietnam and Cambodia with thorough insight into the institutional context in their societies.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Estonia"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["734712"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["GRAND ACCELERATEUR NATIONAL D'IONS LOURDS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "GSI HELMHOLTZZENTRUM FUER SCHWERIONENFORSCHUNG Gmbh", "THE HENRYK NIEWODNICZANSKI INSTITUTE OF NUCLEAR PHYSICS, POLISH ACADEMY OF SCIENCES", "NUCLEOPOLIS POLE NORMAND DES SCIENCES NUCLEAIRES ET DE LEURS APPLICATIONS"], "EU_Contribution": ["EUR 3 883 390"], "Project_Title": ["International Development of gAnil-spirAL2"], "Total_Cost": ["EUR 3 883 390"], "Country": ["France", "France", "France", "Germany", "Poland", "France"], "Project_ACR": ["IDEAAL"], "Technology_Description": "The objectives of the IDEAAL Project are to explore all possibilities to develop GANIL infrastructure, with its new ESFRI SPIRAL2 facility, in order to ensure its long-term sustainability as one of the premiere European research institutes for nuclear physics, interdisciplinary sciences and related applications. ", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["INFRADEV-03-2016-2017 - Individual support to ESFRI and other world-class research infrastructures"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Other"], "From": ["2017-01-01"], "Project_ID": ["730989"], "Call_for_Proposal": ["H2020-INFRADEV-2016-1"]}, -{"Partners": ["PANEPISTIMIO PATRON", "PANEPISTIMIO PATRON"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Assessing compounds targeting DNA replication licensing complexes as anti-tumor agents"], "Total_Cost": ["EUR 150 000"], "Country": ["Greece", "Greece"], "Project_ACR": ["DynaCOMP"], "Technology_Description": "Cancer is a major clinical, societal and economic burden worldwide and development of novel anti-cancer therapies constitutes a major investment of public and private funds. Despite intense research over decades however, which has led to a much improved understanding of cancer biology, cancer treatment remains a challenge. This is to a large extent due to the genetic heterogeneity of cancer and the ability of cancer cells to escape treatment by constantly undergoing further genetic alterations. During our ERC funded work, we have shown that aberrations in the DNA replication licensing pathway may contribute to the genome plasticity of cancer cells, and appear a common feature of cancer cells. They may however also constitute an Achilles foot, as cancer cells appear more dependent on negative regulators of the licensing system for survival. Cancer cells may therefore be more sensitive than normal cells to compounds targeting this control (inhibition of untimely licensing). We have identified compounds which target the DNA replication licensing inhibitor Geminin. The proposed PoC study will enable us to:", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Greece"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["755284"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["BOGAZICI UNIVERSITESI"], "EU_Contribution": ["EUR 157 734"], "Project_Title": ["Effects of Structural Change on Income Inequality"], "Total_Cost": ["EUR 157 734"], "Country": ["Turkey"], "Project_ACR": ["STRCHANGEINEQ"], "Technology_Description": "This project aims to identify the distributional effects of the structural change phenomenon. It develops a dynamic macroeconomic model that introduces heterogeneities across workers and asset owners into the structural change models. For this purpose, it will focus on growth models with heterogeneous agents and complete asset markets. With this methodology, we will be able to characterize not only the aggregate patterns of structural change, but also its distributional consequences. By uncovering the long term factors behind the evolution of income distribution during structural change, the proposed model will be highly relevant to the most recent debates of rising income inequality in developed countries. The theoretical model will be calibrated to assess and quantify the historical roots of the current distributional picture in U.S. and Europe. In doing so, it will determine the \u201cstructural\u201d level of inequality; a level that is due to the intrinsic forces of structural change. Then any deviations -positive or negative- from this level can be identified as \u201cpolitical\u201d, which would provide a clearer picture of the effects of governmental policies on inequality. This model will be the first in the literature to integrate structural models with distributional issues and will open up a new research area. Finally, the model will be enriched with fiscal policies such as income taxes and productive government spending in order to draw policy conclusions regarding the growth-income inequality relationship in Europe, where boosting economic growth while holding the income inequality at a socially acceptable level has been a major concern in recent years. Therefore, the proposed project will both contribute to advancement of European research and address one of the Societal Challenges targeted by H2020 programs, which is working towards \u201cInclusive, innovative and reflective societies\u201d.", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Turkey"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["753537"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ALMA SISTEMI SAS DI DI IORIO ALESSIO & C", "UNIVERSITY OF SOUTHAMPTON", "MARS SPACE LTD", "UNIVERSITA DEGLI STUDI DI PADOVA", "TECHNOLOGY FOR PROPULSION AND INNOVATION SRL", "THE RESEARCH COMMITTEE OF THE TECHNICAL UNIVERSITY OF CRETE"], "EU_Contribution": ["EUR 792 000"], "Project_Title": ["Plasma Antenna Technologies"], "Total_Cost": ["EUR 792 000"], "Country": ["Italy", "United Kingdom", "United Kingdom", "Italy", "Italy", "Greece"], "Project_ACR": ["PATH"], "Technology_Description": "PATH is intended to promote a collaborative researches focused in the development of high density plasma sources", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Italy"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["734629"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["SINGULARLOGIC ANONYMI ETAIREIA PLIROFORIAKON SYSTIMATON KAI EFARMOGON PLIROFORIKIS", "IQUADRAT INFORMATICA SL", "INSTITUT JOZEF STEFAN", "BANGOR UNIVERSITY", "PANEPISTIMIO THESSALIAS", "LJUBLJANSKI URBANISTICNI ZAVOD DD", "DIMOTIKI EPICHEIRISI YDREFSIS - APOCHETEFSIS SKIATHOU", "IBM Thomas J. Watson Research Center"], "EU_Contribution": ["EUR 1 242 000"], "Project_Title": ["Holistic Surface Water and Groundwater Management for Sustainable Cities"], "Total_Cost": ["EUR 1 242 000"], "Country": ["Greece", "Spain", "Slovenia", "United Kingdom", "Greece", "Slovenia", "Greece", "United States"], "Project_ACR": ["Water4Cities"], "Technology_Description": "Urban water management becomes progressively more challenging in the view of population growth and increasing complexity of water management infrastructure. In this line, there is an ever increase demand from the water providers\u2019 and public authorities\u2019 perspective to critically evaluate the existing water ecosystems at city level in respect to the water supply, waste water treatment, reuse potential and the effect the growing population has on the water ecosystem and endangered species. To enable effective decision making at the entire city level, both surface water and groundwater should be viewed as part of the overall urban water ecosystem with its spatio-temporal availability, quantity and quality and competing uses being taken into account. ", "To": ["2021-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Greece"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-03-01"], "Project_ID": ["734409"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["'Total E-field Reconstruction using a MIchelson TEmporal Scan' for spatio-temporal metrology of ultrashort laser beams"], "Total_Cost": ["EUR 150 000"], "Country": ["France", "France"], "Project_ACR": ["TERMITES"], "Technology_Description": "The technology of femtosecond lasers now makes it possible to reach enormous light intensities with only moderate amounts of energy. These so-called Ultra-High Intensity (UHI) lasers have led to the development of a very active research field, which studies the interaction of light with matter at these extreme intensities. This field is largely motivated by the prospects of generating compact sources of high-energy particles and short-wavelength light, which are being foreseen for applications in particle physics, material science, nuclear fusion technology, medicine. ", "To": ["2018-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-05-01"], "Project_ID": ["727427"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["INNOVACIO I RECERCA INDUSTRIAL I SOSTENIBLE SL"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Advanced Data Modeling and Analysis Applied to next Generation Industry 4.0 settings and the Internet of Things"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["DATAMINE4.0"], "Technology_Description": "DATAMINE4.0 is an IF for Career Development for Natasa Sarafijanovic-Djukic, PhD in Computer/Communication Sciences obtained from EPFL, Switzerland, a researcher in statistical modelling originally from Serbia, whereby she will work in IRIS, a Spanish R&D and advanced engineering SME. The project will study the modeling and analysis of data coming from complex industrial and organizational applications, in order to identify hidden causistic relationships in order to calibrate production and organizational control systems. It is highly multidisciplinary combining data science, statistics, artificial intelligence, telecommunications, specific engineering and organizational domains and information technology processing competences. In line with new paradigms such as Industry 4.0 and the Internet of Things. Although machine learning paradigms have been in existence for several decades, their penetration in the industrial and public organization setting has been limited. The goal is to build calibration and optimization models using advanced statistical and machine learning methods and other artificial intelligence inspired algorithms, for applications in which existing methods have been unsatisfactory. This will have a big impact on productivity and repeatability of winning formulas for key industrial applications such as customized production, public sector applications (e.g. optimization of urban mobility), and food processing. This is in line with findings published by the European Union. The developed data mining solutions will greatly enhance the current performance of the selected applications, allowing them a competitive advantage over current methods. The work will be done in an applied R&D environment in line with the objective for Dr. Natasa Sarafijanovic-Djukic\u2019s career continuation. An engineering approach will be ideally completed with 7 formal scientific trainings, including two academic secondments, each of 2 months.", "To": ["2020-01-07, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-SE - Society and Enterprise panel"], "Coordinated_in": ["Spain"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-01-08"], "Project_ID": ["752907"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF KENT", "UNIVERSITY OF KENT", "UNIVERSITY OF LEEDS", "THE JAMES HUTTON INSTITUTE"], "EU_Contribution": ["EUR 1 953 715,63"], "Project_Title": ["Environmental Spaces and the Feel-Good Factor: Relating Subjective Wellbeing to Biodiversity"], "Total_Cost": ["EUR 1 953 715,63"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom", "United Kingdom"], "Project_ACR": ["RELATE"], "Technology_Description": "We live in a time of profound environmental change. Phenomena such as urbanisation and agricultural intensification have led to ecosystem degradation and species extinctions, and thus a reduction in biodiversity. Yet, while it is now widely asserted in the research, policy and practice arenas that interacting with nature is fundamental to human wellbeing, there is a paucity of evidence characterising how biodiversity, the living component of nature, plays a role in this accepted truth. With RELATE, I will pioneer a completely novel approach to investigating this challenging problem, innovating through interdisciplinary (human geography, environmental psychology, economics and ecology) integration and the use of both qualitative and quantitative methods. As such, RELATE will initiate a step-change in our understanding of how nature underpins human wellbeing. Three objectives will be met: (1) explore how people relate to different biodiversity attributes (particular morphologies, sounds, smells, textures, behaviours and/or cultural meanings associated with species), positively and negatively, across all classes of cultural ecosystem service and types of human-nature experience (intentional, incidental, indirect, thereness); (2) quantify variation in how people value, or not, different biodiversity attributes using a range of monetary and non-monetary valuation techniques, including new subjective wellbeing measures; (3) understand how co-occurrence between biodiversity and people may alter across space/time (both seasonal and inter-decadal), and the impact this may have on human-biodiversity relationships. The crucial trade-offs decision-makers tasked with managing environmental spaces have to make between multiple biodiversity, individual and societal deliverables cannot be optimised until we understand human-biodiversity relationships specifically. Consequently, RELATE will deliver a timely, rich and holistic evidence-base, supported by transformative science.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2017-10-01"], "Project_ID": ["726104"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["THE UNIVERSITY OF EXETER", "THE UNIVERSITY OF EXETER"], "EU_Contribution": ["EUR 2 249 834"], "Project_Title": ["Emergent Constraints on Climate-Land feedbacks in the Earth System"], "Total_Cost": ["EUR 2 249 834"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["ECCLES"], "Technology_Description": "The Land Biosphere is a critical component of the Earth System, linking to climate through multiple feedback processes. Understanding these feedback processes is a huge intellectual challenge. In part because of the pioneering work of the PI (Cox et al., 2000), many of the climate projections reported in the IPCC 5th Assessment Report (AR5) now include climate-carbon cycle feedbacks. However the latest Earth System Models (ESMs) continue to show a huge range in the projected responses of the land carbon cycle over the 21st century. This uncertainty threatens to undermine the value of these projections to inform climate policy. This project (ECCLES) is designed to produce significant reductions in the uncertainties associated with land-climate interactions, using the novel concept of Emergent Constraints - relationships between future projections and observable variations in the current Earth System that are common across the ensemble of ESMs. Emergent Constraints have many attractive features but chief amongst these is that they can make ensembles of ESMs more than the sum of the parts - allowing the full range of ESM projections to be used collectively, alongside key observations, to reduce uncertainties in the future climate. The project will deliver: (i) a theoretical foundation for Emergent Constraints; (ii) new datasets on the changing function of the land biosphere; (iii) Emergent Constraints on land-climate interactions based on observed temporal and spatial variations; (iv) a new generation of scientists expert in land-climate interactions and Emergent Constraints. ECCLES will benefit from the expertise and experience of the PI, which includes training as a theoretical physicist, an early career developing models of the land biosphere for ESMs, and a current career in a department of mathematics where he is at the forefront of efforts to develop and apply the concept of Emergent Constraints (Cox et al., 2013, Wenzel et al., 2016).", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["742472"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "UNIVERSITY OF CAPE TOWN"], "EU_Contribution": ["EUR 1 998 885"], "Project_Title": ["How a mutualism evolves: learning, coevolution, and their ecosystem consequences in human-honeyguide interactions"], "Total_Cost": ["EUR 1 998 885"], "Country": ["United Kingdom", "United Kingdom", "South Africa"], "Project_ACR": ["Honeyguides-Humans"], "Technology_Description": "Species interactions such as mutualism, parasitism and predation underpin much of life\u2019s diversity. We aim to understand the mechanistic role of learnt traits in the origin and maintenance of mutualistic interactions between species, and to test their evolutionary and ecological consequences. To do so, we shall study a remarkable mutualism: the foraging partnership between an African bird species, the greater honeyguide Indicator indicator, and the human honey-hunters whom it guides to bees\u2019 nests. Honeyguides know where bees\u2019 nests are located and like to eat beeswax; humans have the ability to subdue the bees and open the nest, thus exposing beeswax for the honeyguides and honey for the humans. This model system gives us a wonderful opportunity to study mutualisms, because local human and honeyguide populations vary strikingly in whether and how they interact, and because we can readily manipulate these interactions experimentally. We have already demonstrated that it is fully feasible to carry out observational and experimental work at a study site we have established in cooperation with a honey-hunting community in northern Mozambique. Here, and at a series of comparative field sites we have identified in south-eastern Africa, we shall ask: is learning involved in maintaining a geographical mosaic of honeyguide adaptation to local human cultures? How does reciprocal communication between humans and honeyguides mediate their interactions? What are the effects of cultural co-extinctions on each partner and their ecosystems, and how quickly can such cultures be re-ignited following their loss? In so doing we shall test for the first time the hypothesis that reciprocal learning can give rise to matching cultural traits between interacting species. Understanding the role of such phenotypic plasticity is crucial to explain how and why the outcome of species interactions varies in space and time, and to predict how they will respond to a rapidly changing world.", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["725185"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER", "ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA", "PHILIPPS UNIVERSITAET MARBURG", "CARL ZEISS VISION INTERNATIONAL GMBH"], "EU_Contribution": ["EUR 891 000"], "Project_Title": ["PLAsticiTY of Perceptual space Under Sensorimotor interactions"], "Total_Cost": ["EUR 1 066 500"], "Country": ["Germany", "Italy", "Germany", "Germany"], "Project_ACR": ["PLATYPUS"], "Technology_Description": "Space is the foundational characteristic of visual perception and we generally perceive it as continuous and uniform. Behavioural measurements and the properties of our sensory systems however, demonstrate that this is an illusory situation and our percept is constructed by the brain. One example is our lack of awareness of the blind spot that exists in each eye. Space is non-uniformly represented in the visual brain and this representation is dynamically influenced by motor behaviour, in particular by eye movements. The PLATYPUS consortium will investigate the dynamic nature of spatial sensation and perception, focussing on the continuous mutual interaction of motor behaviour and perception. Our research objectives integrate human behavioural and cutting edge non-human primate electrophysiological research techniques and focus on translation of basic into applied research. Focussing on the adaptive nature of vision and action, strategies to perturb and probe perceptual space and geometry will allow measurement of spatial and geometrical perception in humans and the representation of such in non-human primates. This research will extend to applications for people wearing progressive lenses which distort action and space perception, patients with a blind area in their visual field and for virtual reality technology development. PLATYPUS researchers will grow existing and establish new collaborative teams, sharing research techniques, knowledge and mentoring between established and with upcoming researchers in academia and industry. Individuals will benefit from intense scientific and career development training while institutions will benefit from the exchange of state-of-the-art techniques. The ultimate outcome will be increased understanding of the continuously updating neural construction of space and the production of assistive technologies for people needing corrective lenses, with ocular or visual discontinuity and for the growing virtual reality industry.", "To": ["2021-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-07-01"], "Project_ID": ["734227"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["CEMM - FORSCHUNGSZENTRUM FUER MOLEKULARE MEDIZIN GMBH", "CEMM - FORSCHUNGSZENTRUM FUER MOLEKULARE MEDIZIN GMBH"], "EU_Contribution": ["EUR 146 668"], "Project_Title": ["Chemical Hematology: breaking resistance of hematological malignancies through personalized drug trials"], "Total_Cost": ["EUR 146 668"], "Country": ["Austria", "Austria"], "Project_ACR": ["chemos"], "Technology_Description": "Personalized medicine aspires to provide optimal therapy in real-time during patient treatment, however current methodology falls short to deliver this in a robust manner. With this in mind, we invented a method for the screening of thousands of drug responses in small samples of an individual\u2019s peripheral blood by automated microscopy and single-cell image analysis. We termed this method pharmacoscopy. In the course of carrying out the i-FIVE ERC grant project plan, we began screening for novel anti-viral or immune modulating drugs. In the quest to increase the physiological relevance of our screening settings, we investigated the possibility of using peripheral blood cells or bone marrow from individuals. We have thus far been able to show that the approach allows for the screening of anti-inflammatory properties of compounds, and to score for distinct sub-population specific cell cytotoxicity profiles of clinical anti-neoplastic agents through the tracking of fluorescent antibodies and probes. Moreover, we have been able to show that the approach empowers the therapeutic decision-making capability of hema-oncologists in a concrete clinical setting using primary myelofibrosis and lymphoma as test diseases. With funding from this grant, we intend to obtain further clinical data through retrospective trials, and incorporate the results into an information package attractive enough to draw the attention of potential investors. We have secured the intellectual property rights and have assembled the know-how required to enable commercialization efforts. With the unique image-based single cell analysis of human liquid tissues, we believe that chemos has the potential to develop into a service that enables and advances personalized medicine and drug discovery for a broad spectrum of hematological disorders.", "To": ["2017-09-30, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Austria"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2016-10-01"], "Project_ID": ["727416"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES"], "EU_Contribution": ["EUR 2 349 898"], "Project_Title": ["Adaptive Actin Architectures"], "Total_Cost": ["EUR 2 349 898"], "Country": ["France", "France", "France"], "Project_ACR": ["AAA"], "Technology_Description": "Although we have extensive knowledge of many important processes in cell biology, including information on many of the molecules involved and the physical interactions among them, we still do not understand most of the dynamical features that are the essence of living systems. This is particularly true for the actin cytoskeleton, a major component of the internal architecture of eukaryotic cells. In living cells, actin networks constantly assemble and disassemble filaments while maintaining an apparent stable structure, suggesting a perfect balance between the two processes. Such behaviors are called \u201cdynamic steady states\u201d. They confer upon actin networks a high degree of plasticity allowing them to adapt in response to external changes and enable cells to adjust to their environments. Despite their fundamental importance in the regulation of cell physiology, the basic mechanisms that control the coordinated dynamics of co-existing actin networks are poorly understood. In the AAA project, first, we will characterize the parameters that allow the coupling among co-existing actin networks at steady state. In vitro reconstituted systems will be used to control the actin nucleation patterns, the closed volume of the reaction chamber and the physical interaction of the networks. We hope to unravel the mechanism allowing the global coherence of a dynamic actin cytoskeleton. Second, we will use our unique capacity to perform dynamic micropatterning, to add or remove actin nucleation sites in real time, in order to investigate the ability of dynamic networks to adapt to changes and the role of coupled network dynamics in this emergent property. In this part, in vitro experiments will be complemented by the analysis of actin network remodeling in living cells. In the end, our project will provide a comprehensive understanding of how the adaptive response of the cytoskeleton derives from the complex interplay between its biochemical, structural and mechanical properties.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["741773"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["ISTITUTO EUROPEO DI ONCOLOGIA SRL", "ISTITUTO EUROPEO DI ONCOLOGIA SRL"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Dissecting the Function of Multiple Polycomb Group Complexes in Establishing Transcriptional Identity"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Italy", "Italy"], "Project_ACR": ["DissectPcG"], "Technology_Description": "The activities of the Polycomb group (PcG) of repressive chromatin modifiers are required to maintain correct transcriptional identity during development and differentiation. These activities are altered in a variety of tumours by gain- or loss-of-function mutations, whose mechanistic aspects still remain unclear.", "To": ["2022-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Italy"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-11-01"], "Project_ID": ["725268"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER", "NEDERLANDSE ORGANISATIE VOOR WETENSCHAPPELIJK ONDERZOEK", "BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION", "ETHNIKO DIKTYO EREVNAS TECHNOLOGIAS AE", "INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK", "INSTITUTE OF INFORMATION AND COMMUNICATION TECHNOLOGIES", "GENIAS BENELUX BV", "STICHTING SURF", "URANUS COMPUTING LTD"], "EU_Contribution": ["EUR 989 537,50"], "Project_Title": ["e-Infrastructure Reflection Group Support Programme 5"], "Total_Cost": ["EUR 989 537,50"], "Country": ["Germany", "Netherlands", "Spain", "Greece", "Poland", "Bulgaria", "Netherlands", "Netherlands", "United Kingdom"], "Project_ACR": ["e-IRGSP5"], "Technology_Description": "Project Summary", "To": ["2018-11-30, ongoing project"], "Meta": [""], "Topic_s": ["INFRASUPP-03-2016 - Support to policies and international cooperation for e-infrastructures"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-12-01"], "Project_ID": ["730954"], "Call_for_Proposal": ["H2020-INFRASUPP-2016-1"]}, -{"Partners": ["INSTYTUT BIOLOGII DOSWIADCZALNEJ IM. M. NENCKIEGO POLSKIEJ AKADEMII NAUK", "INSTYTUT BIOLOGII DOSWIADCZALNEJ IM. M. NENCKIEGO POLSKIEJ AKADEMII NAUK"], "EU_Contribution": ["EUR 1 312 500"], "Project_Title": ["Functional connectomics of the amygdala in social interactions of different valence"], "Total_Cost": ["EUR 1 312 500"], "Country": ["Poland", "Poland"], "Project_ACR": ["CoSI"], "Technology_Description": "Understanding how brain controls social interactions is one of the central goals of neuroscience. Whereas social interactions and their effects on the emotional state of an individual are relatively well described at the behavioral level, much less is known about neural mechanisms involved in these very complex phenomena, especially in the amygdala, a key structure processing emotions in the brain.", "To": ["2021-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Poland"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2016-12-01"], "Project_ID": ["715148"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "UNIVERSITE PARIS DIDEROT - PARIS 7", "NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "RIJKSUNIVERSITEIT GRONINGEN", "Heinrich-Pette-Institute, Leibniz-Institut fuer experimentelle Virologie", "SERVICIO MADRILENO DE SALUD", "FASMATECH EPISTIMONIKI KAI TECHNOLOGIKI ANONYMI ETAIREIA"], "EU_Contribution": ["EUR 7 148 586,25"], "Project_Title": ["Optomechanics for Virology"], "Total_Cost": ["EUR 7 148 586,25"], "Country": ["Spain", "France", "Netherlands", "France", "Netherlands", "Germany", "Spain", "Greece"], "Project_ACR": ["VIRUSCAN"], "Technology_Description": "Viral infections diagnosis demands novel, cheaper and rapid technologies to overcome present constraints. Current gold standard for diagnosis of viral infections is based on pathogen-targeted nucleic acid identification; thus, it cannot discern infectious stages from latent ones and it demands time consuming adjustments when mutations occur or new emerging viruses are to be included in the diagnostic protocols. Lately, optomechanics has served to fundamental advancements in physics, from gravitational wave detection to the study of mechanical quantum ground states but it has not yet delivered its full applicability potential. ", "To": ["2021-10-31, ongoing project"], "Meta": [""], "Topic_s": ["FETPROACT-01-2016 - FET Proactive: emerging themes and communities"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-11-01"], "Project_ID": ["731868"], "Call_for_Proposal": ["FETPROACT-2016"]}, -{"Partners": ["UNIVERSITY OF SOUTHAMPTON"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Ocean Interaction with Antarctic Ice Shelves"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["OceanIS"], "Technology_Description": "The primary goal OceanIS is to constrain the contribution of changes in Southern Ocean circulation to the recent acceleration in Antarctic Ice Sheet mass loss. Improving our knowledge of ice shelf\u2013ocean interactions is a critical step toward reducing uncertainty in future sea level rise projections. Ice shelves are coastal areas of floating ice that extend from an ice sheet out over the ocean, and their destabilization can trigger rapid ice discharge. It is now evident that ocean\u2013driven basal melt is the major cause of ice loss from Antarctica\u2019s fringing ice shelves. However much of the fundamental dynamics of how the ocean delivers heat to the ice shelves remains unresolved. Progress in this area requires bringing together the fields of ice shelf\u2013ocean interactions and large\u2013scale Southern Ocean oceanography. The Southern Ocean overturning entails the upwelling of Circumpolar Deep Water (CDW) offshore Antarctica. The Antarctic Circumpolar Current has shifted poleward, the impact of which, e.g. over the upwelling of CDW, remains unknown. Since CDW is linked to the highest ice shelf thinning rates yet observed, the variability of the CDW properties and its interaction with the ice shelves is the focus of this proposal. To do this, OceanIS integrates, for the first time, several unique data sets, which extend from the deep ocean to the sub\u2013ice shelf environment. These include data from the Argo network, instrumented seals, and measurements from the only decadal\u2013scale record of ocean properties beneath an Antarctic ice shelf, the Amery ice shelf. OceanIS will help to test which of the suite of current climate models shows ice\u2013ocean interaction processes and CDW variability that are most in line with reality. Given that the forcings driving Southern Ocean changes are expected to continue in the future, results of OceanIS will be a major step toward reducing the uncertainty that surrounds the future stability of the Antarctic Ice Sheet and sea level rise projections.", "To": ["2018-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["661015"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["STICHTING KATHOLIEKE UNIVERSITEIT"], "EU_Contribution": ["EUR 260 929,80"], "Project_Title": ["Ideas and Legitimating Discourse in EU and US Agricultural Policy-Making and their Implications for Transatlantic Trade Relations"], "Total_Cost": ["EUR 260 929,80"], "Country": ["Netherlands"], "Project_ACR": ["AGRIDEASCOURSE.TRADE"], "Technology_Description": "This project comparatively investigates divergence and convergence in agricultural policy ideas and policies in the EU and the US and their interaction with multilateral and transatlantic trade negotiations. Applying an innovative Discursive Institutionalist approach, it uncovers whether and how ideas and discourse affect processes of policy transformation. It thus contributes to an \u2018ideational turn\u2019 in the field of Agricultural Policy Studies which is currently dominated by rationalist interest-based explanations. The outcomes of this research will not only explain the dynamics of agricultural policy change and their effect on past trade negotiations, it will also provide policy makers with insights in the opportunities and limits to develop agricultural policies that are both domestically acceptable and conducive to ongoing transatlantic and international trade negotiations (e.g. TTIP and WTO). This is highly significant considering the important role of agricultural trade policies in tackling the pressing food and environmental challenges of today and tomorrow.", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-08-01"], "Project_ID": ["659838"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITY OF NEWCASTLE UPON TYNE"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Measuring Quality of Life in the general population and Roma minority in Romania: implications for health policies and economic evaluations"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["QoLRO"], "Technology_Description": "The importance of health related quality of life (HRQoL) data in research, clinical practice and health policy has significantly increased over the past decade. EQ-5D-5L is one of the most widely used instruments to measure HRQoL worldwide. Nevertheless, the quality of life of the Romanian general population or ethnic minorities has never been assessed before with EQ-5D-5L. Here, I propose to use EQ-5D-5L to provide locally robust HRQoL data for Romania to support reimbursement decisions and public health interventions in wider and vulnerable groups, such as the Roma minority. A representative sample of the Romanian general population and Roma minority will be recruited and face-to-face interviews will be conducted to explore differences in HRQoL according to sociodemographic characteristics, socioeconomic status and ethnicity. Additionally, population norms and social preferences for different health states (tariff) for EQ-5D-5L will be obtained. ", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["748612"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["POLITECHNIKA POZNANSKA", "UNIWERSYTET PRZYRODNICZY W POZNANIU*", "INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK", "UNIWERSYTET IM. ADAMA MICKIEWICZA W POZNANIU", "AKADEMIA WYCHOWANIA FIZYCZNEGO IM EUGENIUSZA PIASECKIEGO", "UNIWERSYTET EKONOMICZNY W POZNANIU"], "EU_Contribution": ["EUR 133 347,50"], "Project_Title": ["Wielkopolska Researchers\u2019 Night welcomes - Let the experience of the Night last every day!"], "Total_Cost": ["EUR 140 347,50"], "Country": ["Poland", "Poland", "Poland", "Poland", "Poland", "Poland"], "Project_ACR": ["EVERYDAYNIGHT"], "Technology_Description": "\"Researchers\u2019 Night again in Poznan! EVERYDAYNIGHT! Wielkopolska Researchers\u2019 Night welcomes - Let the experience of the Night last every day! Come and see how research influences your every-day life! Reveal the interdisciplinary nature of science and learn how different scientific fields complement each other, making our life better.", "To": ["2017-11-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-NIGHT-2016 - European Researchers' Night"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Poland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["722937"], "Call_for_Proposal": ["H2020-MSCA-NIGHT-2016"]}, -{"Partners": ["WEIZMANN INSTITUTE OF SCIENCE", "WEIZMANN INSTITUTE OF SCIENCE"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["MRI diagnosis using a single-shot imaging technique with unprecedented robustness to field inhomogeneities"], "Total_Cost": ["EUR 150 000"], "Country": ["Israel", "Israel"], "Project_ACR": ["X-Imaging"], "Technology_Description": "This project seeks to exploit cross-term spatiotemporal encoding (xSPEN), a single-shot MRI modality that we introduced last year as part of our efforts to develop new ultrafast techniques in nuclear magnetic resonance. Besides delivering single-shot images in tens of milliseconds, xSPEN exhibits an unprecedented resilience to field inhomogeneities enabling it to access regions that have so far never been scanned by single-scan MRI. Over the last year we have confirmed this and further developed these single-shot measurements, combining it with sequences and algorithms enabling their use in kinetic and diffusivity studies. This PoC proposes to employ these new methods to tackle three problems that pose open challenges in diagnostic radiology, due to their involvement of tissue-metal and tissue-air interfaces subject to strong susceptibility distortions. These include (i) accessing physiological information in the proximity of metal implants; (ii) diagnosing cholesteatomas, a middle-ear growth of chronic recurrence with characteristic diffusion parameters; and (iii) examining and diagnosing optic nerve neurofibromatosis tumours by diffusion and by dynamic contrast enhanced MRI. By enabling non-invasive, mostly diffusion-based characterisations of these challenging radiological problems, xSPEN will provide hitherto unavailable opportunities to perform repetitive, differential diagnoses of diseases whose permanent solution demands invasive radiation and/or surgery procedures. This can in turn free patients from what could be unnecessary, highly invasive and dangerous operations, preserving a normal lifestyle, and alleviating associated healthcare costs. Furthermore, as despite its uniqueness xSPEN is compatible with thousands of contemporary clinical MRI machines, validating its diagnostic use on a suitable cohort of volunteers and patients should open a world-wide market of radiological imaging applications, with a life time of decades.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["751106"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Neuron/mast cell interactions in skin diseases"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["NEMESIS"], "Technology_Description": "Atopic dermatitis (AD) is a chronic skin inflammatory disease affecting 10-20% of children worldwide. The etiology of AD is incompletely understood, but many elements (e.g., genetic, environmental or immune) are thought to contribute to the pathogenesis. The skin is specifically enriched in mast cells (MCs) and innervated by a network of abundant sensory neurons. New findings suggest that nociceptive sensory neurons (nociceptors) might regulate the development of immune responses. Skin MCs also express a transcriptional signature of genes encoding neuropeptide receptors (e.g., Mrgprb2: the receptor for the substance P [SP]), through which MCs might uniquely interact with nociceptors. Based on solid preliminary data, the central hypothesis of this project is that SP-producing nociceptor/Mrgprb2+ MC interactions play a critical role in AD pathogenesis. Using a relevant mouse model of AD and innovative imaging approaches, we now aim to elucidate [1] which subset(s) of nociceptor is involved in AD, [2] how SP+ nociceptor/Mrgprb2+ MC interact in our model and in skin lesions from patients diagnosed with AD and [3] how such interactions might favor skin barrier dysfunction. This project promises to provide new insights into skin neuro-immune interactions and may lead to the discovery of new therapeutic targets to treat AD pathology.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2017-07-01"], "Project_ID": ["749629"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["WIRTSCHAFTSUNIVERSITAT WIEN", "WIRTSCHAFTSUNIVERSITAT WIEN"], "EU_Contribution": ["EUR 1 999 908,75"], "Project_Title": ["Spatially explicit material footprints: fine-scale assessment of Europe\u2019s global environmental and social impacts"], "Total_Cost": ["EUR 1 999 908,75"], "Country": ["Austria", "Austria"], "Project_ACR": ["FINEPRINT"], "Technology_Description": "In the era of globalisation, supply chains are increasingly organised on the international level, thus disconnecting final consumption from the location of material extraction and related environmental and social impacts. Reducing these global impacts \u2013 or footprints \u2013 of European consumption is a major societal and scientific challenge. Methods to assess teleconnections between distant places of raw material extraction and consumption along global supply chains have improved significantly, with multi-regional input-output (MRIO) analysis being the most prominent method applied. However, the limited spatial resolution of MRIO models distorts footprint calculations, as specific properties of raw materials as well as impacts of extraction can vary significantly within production countries. I therefore propose a new method for the calculation of fine-scale material consumption footprints. It will encompass (1) a spatial assessment of global material extraction on a high-resolution grid and (2) a detailed physical model that tracks raw materials from the location of extraction via international transport facilities to processing industries in importing countries. Integrating this very detailed spatial information with a MRIO model will enable the first fine-scale assessment of European countries\u2019 material footprints, overcoming prevailing aggregation errors in footprint indicators. Furthermore, I will investigate environmental and social impacts related to material footprints through linking the spatially explicit multi-regional material flow model with datasets on impacts related to raw material extraction, such as increasing water scarcity, deforestation and mining conflicts. This project will not only lift the accuracy of footprint models to a new level, but will also open up a range of options for sustainability assessments of specific commodity flows. Building on this knowledge, targeted policy instruments for sustainable product supply chains can be designed.", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["725525"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSIDAD POMPEU FABRA", "UNIVERSIDAD POMPEU FABRA", "FUNDACION CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III"], "EU_Contribution": ["EUR 2 499 949"], "Project_Title": ["Tissue regeneration and aging: the decisive quiescent stem-cell state"], "Total_Cost": ["EUR 2 499 949"], "Country": ["Spain", "Spain", "Spain"], "Project_ACR": ["STEM-AGING"], "Technology_Description": "The basic mechanisms of stem cell malfunction during aging are poorly understood even though they underlie the regenerative decline of most organs and tissues as we age. Based on our recent contributions (Nature 2014, Nature 2016), the fields of tissue regeneration and aging converge on the key role of the quiescent state, the preferred state of stem cells in low turnover tissues such as skeletal muscle. Our unifying hypothesis is that stem-cell quiescence maintenance, which requires active proteostasis (protein homeostasis), lies at the basis of stemness, and that its substitution by a senescence state in aging impairs regeneration. How these variables connect to drive stem cell aging is not known. Crucial experimental systems in this proposal are sensitive reporter mice for proteostasis, senescence and quiescence/fate in aging muscle stem cells. The project is divided as follows: Objective 1. Proteostasis and stem cell quiescence maintenance: tracing proteostasis in quiescent stem cells from autophagy and chaperone-mediated autophagy (CMA) reporter mice during aging / impact of autophagy/CMA loss on quiescence and regeneration / molecular regulators of proteostasis. Objective 2. Proteostasis and quiescent stem cell heterogeneity and fate: asymmetric segregation of proteotoxic waste as an instructor of stem cell heterogeneity and regenerative fate. Objective 3. The quiescence-to-senescence-switch in aging muscle stem cells: tracing and isolating senescent stem cells in senescence-cell reporter mice during aging / impact of senescent cell ablation on regenerating aged muscle. Objective 4. Circadian regulation in the quiescent stem-cell state: impact of aging on circadian rhythms and consequences for quiescence maintenance and regeneration. We expect that completion of these objectives will provide new fundamental knowledge on stem-cell biology, regeneration and aging.", "To": ["2022-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2017-11-01"], "Project_ID": ["741966"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich"], "EU_Contribution": ["EUR 2 499 887"], "Project_Title": ["Cybergenetics: Theory and Design Tools for Biomolecular Control Systems"], "Total_Cost": ["EUR 2 499 887"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["CyberGenetics"], "Technology_Description": "We propose to develop a new theory and design tools for the estimation and real-time control of living cells. The control systems designed using these tools will precisely and robustly steer the dynamic behavior of living cells in real time to achieve desired objectives. Cells would be controlled either collectively at the population level, or individually as single cells. The control systems achieving this regulation will be realized either on a digital computer that is interfaced with living cells, or using de novo genetic circuits that are introduced into the cells where they are designed to function as molecular control systems. Our methods will explicitly confront the numerous challenges brought about by the special environment of the cell including nonlinearity, stochasticity, cell-to-cell variability, metabolic burden, etc. The theory and methods developed in this project will thus enable the systematic, rational, and effective feedback control of living cells at the gene level, and will lay the foundation for a new corresponding body of knowledge which we call ``Cybergenetics''. It will also open new research directions in the areas of control theory and estimation.", "To": ["2022-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["743269"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "ERNST-MORITZ-ARNDT-UNIVERSIT\u00c4T GREIFSWALD", "FAKULTNI NEMOCNICE U SV. ANNY V BRNE", "WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER", "ENANTIS S.R.O", "RIJKSUNIVERSITEIT GRONINGEN", "BEN-GURION UNIVERSITY OF THE NEGEV", "MEDIMMUNE LIMITED", "JOHNSON MATTHEY PLC", "UNIVERSITE CATHOLIQUE DE LOUVAIN"], "EU_Contribution": ["EUR 3 827 031,48"], "Project_Title": ["Directed Protein Evolution for Synthetic Biology and Biocatalysis"], "Total_Cost": ["EUR 3 827 031,48"], "Country": ["United Kingdom", "Germany", "Czech Republic", "Germany", "Czech Republic", "Netherlands", "Israel", "United Kingdom", "United Kingdom", "Belgium"], "Project_ACR": ["ES-Cat"], "Technology_Description": "ES-Cat will use directed evolution as a tool to reproduce Nature's remarkable ability to generate molecular machines - in particular enzymes \u2013 that perform at levels near perfection. Instead of seeing rational and combinatorial approaches as alternatives, we combine them in this network to achieve a \u2018smarter\u2019 and more efficient exploration of protein sequence space. By harnessing the forces of Darwinian evolution and design in the laboratory we want to (i) screen large and diverse libraries for proteins with improved and useful functions, (ii) optimize existing proteins for applications in medicine or biotechnology and (iii) provide a better understanding of how existing enzymes evolved and how enzyme mechanisms can be manipulated. This Network brings together leading academic and industrial groups with diverse and complementary skills. The range of methodologies represented in ES-Cat allows an integrated approach combining in silico structural and sequence analysis with experimental high-throughput screening selection methods (phage-, ribozyme and SNAP display, robotic liquid handling, lab-on-a-chip/microfluidics) with subsequent systematic kinetic and biophysical analysis. This integration of methods and disciplines will improve the likelihood of success of directed evolution campaigns, shorten biocatalyst development times, and make protein engineering applicable to a wider range of industrial targets. It will also train the next generation of creative researchers ready to fill roles in tailoring enzymes and other proteins for industrial application in synthetic biology efforts to move towards a bio-based economy, rivaling advances that are being made in the US and allowing the EU economy to harvest its evident socio-economic benefits.", "To": ["2021-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2017-03-01"], "Project_ID": ["722610"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["ACADEMISCH ZIEKENHUIS LEIDEN", "ACADEMISCH ZIEKENHUIS LEIDEN"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Oogenesis spotlighted: making mature human oocytes"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["OVO-GROWTH"], "Technology_Description": "Women who survive childhood cancer often fail to conceive because their eggs are damaged by (gonadotoxic) chemotherapy. A major breakthrough has been the possibility to cryopreserve cortical strips of their ovarian tissue for autologous transplantation later in life. This has led to over 40 successful pregnancies worldwide, the latest in the Netherlands. However, the risk of reintroducing cancer cells with the ovarian graft in patients with previous hematopoietic malignancies is too great and alternatives are needed. ", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["725722"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["IBM RESEARCH GMBH", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "UNIVERSITA DEGLI STUDI DI PERUGIA", "ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA", "CINECA CONSORZIO INTERUNIVERSITARIO", "UNIVERSITAT JAUME I DE CASTELLON", "THE QUEEN'S UNIVERSITY OF BELFAST", "GREENWAVES TECHNOLOGIES", "TECHNISCHE UNIVERSITAET KAISERSLAUTERN"], "EU_Contribution": ["EUR 5 990 510"], "Project_Title": ["Open transPREcision COMPuting"], "Total_Cost": ["EUR 5 990 510"], "Country": ["Switzerland", "Switzerland", "France", "Italy", "Italy", "Italy", "Spain", "United Kingdom", "France", "Germany"], "Project_ACR": ["OPRECOMP"], "Technology_Description": "Guaranteed numerical precision of each elementary step in a complex computation has been the mainstay of traditional computing systems for many years. This era, fueled by Moore's law and the constant exponential improvement in computing efficiency, is at its twilight: from tiny nodes of the Internet-of-Things, to large HPC computing centers, sub-picoJoule/operation energy efficiency is essential for practical realizations. To overcome the \u201cpower wall\u201d, a shift from traditional computing paradigms is now mandatory.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["FETPROACT-01-2016 - FET Proactive: emerging themes and communities"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Switzerland"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["732631"], "Call_for_Proposal": ["FETPROACT-2016"]}, -{"Partners": ["COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES", "CONSIGLIO NAZIONALE DELLE RICERCHE", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "\"NATIONAL CENTER FOR SCIENTIFIC RESEARCH \"\"DEMOKRITOS\"\"\"", "SOLVIONIC", "C-TECH INNOVATION LIMITED", "CENTRO RICERCHE FIAT SCPA", "GEMMATE TECHNOLOGIES SRL", "HAUTE ECOLE SPECIALISEE DE SUISSE OCCIDENTALE", "POLITECHNIKA GDANSKA"], "EU_Contribution": ["EUR 4 999 777,50"], "Project_Title": ["MAGnetic nanoparticle based liquid ENergy materials for Thermoelectric device Applications"], "Total_Cost": ["EUR 4 999 778,75"], "Country": ["France", "Italy", "France", "Greece", "France", "United Kingdom", "Italy", "Italy", "Switzerland", "Poland"], "Project_ACR": ["MAGENTA"], "Technology_Description": "MAGENTA proposes a brand new technological path in thermoelectric materials research for waste-heat recovery applications. The originality of the project is based on the newly discovered thermal-to-electric energy conversion capacity of ionic-liquids and ferrofluids; i.e., colloidal dispersions of magnetic nanoparticles in ionic liquids (IL-FFs). It is an inter-disciplinary and cross-sector R&D project combining concepts and techniques from physics, chemistry and electrochemistry with an active participation from 3 SME and 1 industrial partners implicated in the materials supply-chain, the device design/performance and the market-uptake assessment. Both experimental and theoretical approaches will be employed to build foundational knowledge on novel magneto-thermoelectric phenomena in ferrofluids. Computational simulations will allow \u2018bottom-up\u2019 construction of IL-FFs with optimal conditions for harvesting energy. The end-products of MAGENTA, application specific magneto-thermoelectric materials and devices, will provide innovation leadership to European companies in waste-heat recovery industries. The lead-user industries targeted by MAGENTA are automobile and microelectronic sectors, but demonstration-type thermoelectric generators will also be produced for public outreach actions on waste-heat recovery technologies. Through its foundational, interdisciplinary and cross-sector research & innovation actions, the consortium will become a \u201cseed community\u201d for building an innovation ecosystem around the novel magneto-thermoelectric technology, presenting long-term impacts on future renewal energy science and technology from which the society as a whole can benefit. Withal, MAGENTA offers breakthrough thermoelectric materials that are versatile, cost-effective and non-toxic to assist the economically and environmentally sustainable energy transition in Europe.", "To": ["2020-12-31, ongoing project |"], "Meta": [""], "Topic_s": ["FETPROACT-01-2016 - FET Proactive: emerging themes and communities"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["731976"], "Call_for_Proposal": ["FETPROACT-2016"]}, -{"Partners": ["KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW"], "EU_Contribution": ["EUR 242 929,80"], "Project_Title": ["Causal study of the role of feedback in the perceptual inference of figure location in the primate visual cortex using targeted optogenetics"], "Total_Cost": ["EUR 242 929,80"], "Country": ["Netherlands"], "Project_ACR": ["OptoFeedback"], "Technology_Description": "The perception of complex visual scenes requires active processing by the brain. The visual cortex is hierarchically organized in several areas which are linked by connections projecting from lower to higher areas (feedforward) and connections projecting from higher to lower areas (feedback). More complicated processing occurs in higher areas such as V4, where neurons encode which side of a border belongs to a figure. Feedback connections are large in number but their function is poorly understood. An important role for feedback has been proposed in probabilistic inference, whereby cortical areas \u201cinfer\u201d the reality in the external world based on the sensory information they receive from lower areas, combined with prior hypotheses projected down from higher areas. ", "To": ["2020-08-29, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Netherlands"], "Activity": ["Research Organisations"], "From": ["2017-08-30"], "Project_ID": ["751387"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FUNDACION PRIVADA INSTITUTO DE SALUD GLOBAL BARCELONA"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["NeuroCOGNitive impact of Air pollution exposures in Childhood: Assessment of air pollution effects on the development of cognition and behaviour in children"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["COGNAC"], "Technology_Description": "Neurological disorders such as Autism Spectral Disorders (ASD) in children are lifelong conditions for which there is no cure,treatment options are very limited AND create huge burdens on children, families and society. Potential long-term consequences of poor cognitive performance and presence of autistic traits are poor social development, low educational achievement, diminished economic productivity and unemployment, mental health issues, and increased risk of antisocial behaviour. In the case of ASD, a lifelong disorder, there is no cure and limited treatment options are available. Therefore, it is essential to identify modifiable risk factors to prevent their onset and prevalence. Air pollution is postulated as a risk factor since it is believed to cause neuroinflammation, oxidative stress and neurodegenerative pathology. Traffic noise shows inconclusive associations with cognitive performance. The experience in cognitive and neurobehavioral development epidemiologic analysis and wide-scale modelling at the host institution, with different modelling approaches and existing models available for UK and London at the partner's institutions, and the experience of exposure assessment methods of the fellow dovetail nicely to accomplish the goal of the COGNAC project. This is to explore the associations between air pollution and noise with cognitive performance and the presence of autistic traits in children using a large children cohort. The innovative aspects of this proposal are combining multi-pollutant and noise exposure, using very detailed maps of these environmental stressors and assessing effects at critical windows of exposure. The scientific impact of this fellowship results from the identification of the effect of air pollution and noise in cognitive development and the presence of autistic traits in children. The skills acquired in this fellowship will be decisive fo establishing me in one of the leaders in environmental health applied to neurocognition.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-10-01"], "Project_ID": ["750531"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF EXETER", "THE UNIVERSITY OF EXETER"], "EU_Contribution": ["EUR 1 931 730"], "Project_Title": ["The Problem of European Misperceptions in Politics, Health, and Science:Causes, Consequences, and the Search for Solutions"], "Total_Cost": ["EUR 1 931 730"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["DEBUNKER"], "Technology_Description": "While some people may simply lack relevant factual knowledge, others may actively hold incorrect beliefs. These factual beliefs that are not supported by clear evidence and expert opinion are what scholars call misperceptions (Nyhan and Reifler 2010). This project is principally about misperceptions\u2014the \u201cfacts\u201d that people believe that simply are not true. What misperceptions do Europeans hold on issues like immigration, vaccines, and climate change? Who holds these misperceptions? What demographic and attitudinal variables are correlated with holding misperceptions? And ultimately, what can be done to help reduce misperceptions? ", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["682758"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["THE UNIVERSITY OF EXETER"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Flexible Hyperspectral Infrared Detectors"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["FLAIR"], "Technology_Description": "One of the major driving forces for current research in electronics is the desire to realize the so-called internet of things, an autonomous information network that enables communication between objects without external human intervention. To this end, much of the research effort in device physics is currently directed into sensors technology, and specifically, to photodetectors. The infrared (IR) region of the spectrum is of particular interest as it can carry information about an object\u2019s temperature, and its chemical composition. IR waves are also used for long-range waveguided communication, as well as short-range free space signaling. In IR systems, the readout noise is reduced by exploiting multicolor IR detection, so-called hyperspectral IR, thus lowering false positive detection.", "To": ["2018-09-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["701704"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["CONSIGLIO NAZIONALE DELLE RICERCHE", "STAZIONE ZOOLOGICA ANTON DOHRN", "THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN", "UNIVERSITETET I TROMSOE", "FUNDACION CENTRO DE EXCELENCIA EN INVESTIGACION DE MEDICAMENTOS INNOVADORES EN ANDALUCIA", "SEALIFE PHARMA GMBH", "ECOAST", "EPI-C SRL", "SEA4US BIOTECNOLOGIA E RECURSOS MARINHOS LDA", "UNIVERSITY OF THE WESTERN CAPE"], "EU_Contribution": ["EUR 373 500"], "Project_Title": ["Ocean Medicines"], "Total_Cost": ["EUR 373 500"], "Country": ["Italy", "Italy", "United Kingdom", "Norway", "Spain", "Austria", "Belgium", "Italy", "Portugal", "South Africa"], "Project_ACR": ["Ocean Medicines"], "Technology_Description": "Marine organisms have the capacity to produce a variety of biologically potent natural products. Such novel molecules have new mechanisms of action and therefore could be used to treat human diseases and enhance the quality of life, especially in the ageing segment of the population. However, although there is growing interest in marine natural products (MNP) as potential therapeutic agents for human age-related diseases, few MNPs have reached clinical trials and the market. To fully exploit these promising biological resources, new strategies in the pipeline as well as a new cohort of cross-disciplinary trained scientists are needed to overcome existing bottlenecks and ensure the production of high value biomolecules. ", "To": ["2019-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2015-12-01"], "Project_ID": ["690944"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["UNIVERSITETET I TROMSOE", "UNIVERSITETET I TROMSOE"], "EU_Contribution": ["EUR 143 933"], "Project_Title": ["A gene expression test in blood for breast cancer"], "Total_Cost": ["EUR 143 933"], "Country": ["Norway", "Norway"], "Project_ACR": ["BLOBREC"], "Technology_Description": "The aim of BLOBREC is to develop a blood-based test for the diagnosis of breast cancer. The test is based on results from gene expression analyses in a hospital based nested case-control study in the Norwegian Women and Cancer postgenome cohort study. The controls are healthy population controls from the same cohort. The innovative potential of a gene expression test is the independency from other test for breast cancer like imaging technologies (mammograms, ultrasound, MR) and pathological diagnosis. As such it could be used by itself or in combination with these other technologies. The idea has been considered by the International Search Authorities to be novel and inventive and thus, considered to be patentable.", "To": ["2016-04-30, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2014 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-05-01"], "Project_ID": ["665633"], "Call_for_Proposal": ["ERC-2014-PoC"]}, -{"Partners": ["ASTON UNIVERSITY"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Structured photonics for advanced fibre lasers"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SPAFIL"], "Technology_Description": "The key goals of the project are: (1) the training of a talented, independent researcher, Dr Amos Martinez, to become a successful leading scientist in the fast growing field of science, technology and industrial applications of fibre lasers, (2) exploring new ways to exploit two-dimensional materials, such as graphene, in photonics through femtosecond laser nanostructuring and developing new classes of light sources for applications in optical communications, medical imaging, industrial manufacturing and metrology. This multidisciplinary project has great implications on laser science, nanotechnology, material science and graphene technologies such as graphene plasmonics, metamaterials, phononics and electronics, and will involve both fundamental and applied research. ", "To": ["2017-07-05, Grant Agreement terminated |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-07-06"], "Project_ID": ["659222"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["RUHR-UNIVERSITAET BOCHUM", "RUHR-UNIVERSITAET BOCHUM", "KOZEP-EUROPAI EGYETEM"], "EU_Contribution": ["EUR 1 999 623"], "Project_Title": ["Jews and Christians in the East: Strategies of Interaction between the Mediterranean and the Indian Ocean"], "Total_Cost": ["EUR 1 999 623"], "Country": ["Germany", "Germany", "Hungary"], "Project_ACR": ["JEWSEAST"], "Technology_Description": "This project analyzes Jews in Eastern Christian communities and Eastern Christian sources, beyond the Byzantine context, namely, relations between Jews and Christian communities in the Middle East Central Asia, the Caucasus, Ethiopia, and South India. In order to obtain a truly accurate understanding of the dynamics of Jewish-Christian relations in the non-Latin world during the Middle Ages, these various regions and traditions must be studied together because they were all profoundly interconnected through the exchange and translation of texts, artistic motifs and techniques, and other goods, via long-distance trade along the \u201csilk road\u201d, the Mediterranean, and the Indian Ocean, which, of course, also entailed the movement and encounter of peoples, Jews and Christians among them. The research team endeavors to answer four intertwined questions: 1) what we can know about actual \u201creal-life\u201d interactions between Jews and a variety of Eastern Christian communities; 2) what were the meanings and functions of invented or rhetorical Jewish identities; 3) what is the significance of Jewish-Christian polemics, both written and visual, in lands or among communities where: a) there were supposedly few to no Jews, or Jewish identity was \u201cinvented\u201d; b) there were Jewish and Christian communities who had the opportunity to be in regular contact with one another; 4) how were Christian stories, laws, biblical interpretations, or motifs in which Jews featured prominently, or Jewish tales and motifs about Christians transformed as they were transported from one cultural milieu to another? Because scholars have examined Jewish relations with Christians, and even Muslims primarily in the context of uneven power relationships; namely Jewish-Christian relations in Western Europe or Byzantium, or Jewish-Muslim relations in the Islamic one leaving Jewish-Christian relations untouched apart from shared communal structures, this project opens a new field.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["647467"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["OSRAM GMBH", "UNIVERSITA DEGLI STUDI DI VERONA"], "EU_Contribution": ["EUR 507 277,80"], "Project_Title": ["Time-lapse understanding of the static and human scene and its lighting"], "Total_Cost": ["EUR 507 277,80"], "Country": ["Germany", "Italy"], "Project_ACR": ["SCENEUNDERLIGHT"], "Technology_Description": "Europe has a strong position in the fast-growing photonics and lighting industry but has to face the fast technological changes and, most importantly, a demand for larger transfer from research to industrial innovation and application. With the introduction of Solid State Lighting (SSL) new targets of energy efficiency were set and smart lighting technology was boosted.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-EID - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-EID)"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["Germany"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["676455"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["EUROPROXIMA BV"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["Development of fast antibody-based screening tests for the detection of harmful mycotoxins in food and feed"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["MycoTest"], "Technology_Description": "The contamination of food and feed with harmful fungal derived mycotoxins is a problem worldwide and worsening. Over 400 different mycotoxins are now known, some of them have been studied in great detail, while the data about toxicity and occurrence for many others are scarce. This information is required to determine the risk in relation to animal and human health and establish maximum permitted levels that do not pose any health concerns. The fast elimination of contaminated food and feed from the supply chain is crucial for the protection of human and animal health as many of these toxins can cause serious diseases both after acute and chronic exposure. The occurrence data cannot be provided without fast and reliable detection methods that allow quantification of these toxic contaminants. This research, therefore, is focused on delivering new fast antibody-based (ELISA) screening methods for the detection of three important mycotoxins: T-2/HT-2, ochratoxin A and sterigmatocystin and on the development of a first multiplex flow-through rapid (FTR) test for the simultaneous detection of mycotoxins in food and feed. These tests could be used by food and feed producers, importers and testing laboratories to assure food and feed safety on the European market. The researcher will work for two years with the food safety company EuroProxima (EP) in the Netherlands that will provide training and support of the development of the commercial analytical assays. The project will be also supported by the partner organisations - Institute for Global Food Security (IGFS) at Queen's University Belfast (QUB) and RIKILT Wageningen UR (RIKILT) who will be hosting secondment phases in order to facilitate the work packages. This project aims to combine academic excellence with specialist SME know-how to work on a project with significant impact on public health and that offers a substantial commercial opportunity.", "To": ["2017-09-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-10-01"], "Project_ID": ["655119"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["VIB", "VIB"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["employing protein aggregation as an antibacterial design strategy"], "Total_Cost": ["EUR 150 000"], "Country": ["Belgium", "Belgium"], "Project_ACR": ["PeptIn"], "Technology_Description": "Antibiotic resistance is increasing globally at such a pace that many experts fear the dawn of the post-antibiotic era if we fail to meet the urgent need for novel therapeutics. We evaluated if the working hypothesis of the MANGO ERC project that protein aggregation is driven by sequence specific interactions can be exploited to generate aggregates that are specifically toxic to bacteria without affecting mammalian cells. In particular we examined if peptides encoding aggregation-prone sequence segments of bacterial proteins can display antimicrobial activity by initiating aggregation in bacteria but not in mammalian cells. Unbiased in vitro screening of aggregating peptides lead to the identification of several hits that are strongly bactericidal against drug resistant gram+ S aureus strains, and others against pathogenic gram- E coli strains. The peptides cured mice from bacterial sepsis without apparent toxic side effects. The peptides enter and accumulate in the bacterial cytosol where they cause aggregation of bacterial polypeptides and the formation of inclusion bodies. Although the precise chain of events that leads to cell death remains to be elucidated, the ability to tap into aggregation-prone sequences of bacterial proteomes to elicit antimicrobial activity represents a rich and unexplored chemical space to be mined in search of novel therapeutic strategies to fight infectious diseases that are increasingly threatening global healthcare. However, given the novelty of this concept, the viability of aggregating peptides as antimicrobial therapeutics needs to be further advanced in order to consolidate the already significant interest from the pharmaceutical industry. In the current proposal we outline a series of experiments designed to address some of the key questions that were raised by potential investors and experts from the pharmaceutical sector to whom we presented the current data package.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Belgium"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-07-01"], "Project_ID": ["766811"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["THE UNIVERSITY OF EXETER"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Christian Diversity in Late Antique Sirmium (ca 350 \u2013 ca 450): A Historical, Literary and Theological Study"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["CHRISLAS"], "Technology_Description": "This research follows a Christian community situated on the edge of Central Europe and the Balkans during an intense period of struggles towards its self-definition amongst religious dissent, socio-cultural diversity and political and military hardships. All these resulted in a regionally coloured Christianity, the main characteristics of which are visible in the material as well as literary heritage of this community. The setting is the 4th - 5th century A.D. Sirmium \u2013 modern Sremska Mitrovica (Serbia). At the time, Sirmium was one of the capitals of the Roman province Pannonia, an area which now comprises parts of modern Austria, Hungary, Croatia and Serbia. It is vital to understand the history of religious diversity and identity in that region, which continues to puzzle Europe with its rich cultural heritage, but also with its controversial political, ethnical and religious past. This research will contribute to the better understanding of European culture, and its religious and cultural memory, reinforcing the idea that the concrete realization of Christian identity varies according to context and that there is a complex relationship between religious diversity and identity in a particular place. Once verified with regard to Sirmium, this type of research can be extended to other places / regions in the late antique Mediterranean world. In particular, the applicant envisages a long-term research project on Christian identity in Roman Pannonia and a network of late antique Middle Danube studies. All these will lead to the pursuit of a tenure-track academic position that will enable the applicant to implement this larger Pannonian research. The University of Exeter is the ideal location: it is a growing centre of Late Antique studies, with a cluster of research projects on \u2018Identities and beliefs\u2019 in the ancient world. The fellow will extend her skills by being in Exeter, and will contribute her linguistic and historical expertise to their on-going research.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["658265"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE UNIVERSITY OF EXETER"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Complex parasite communities as drivers of bacterial immunity"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["PHAGECOM"], "Technology_Description": "CRISPR-Cas is one of several distinct bacterial defence mechanisms that provide immunity against viruses (phages) and other mobile genetic elements (MGEs; e.g. plasmids). My research aims at understanding how CRISPR-Cas-mediated immunity is affected by the complexity of MGE communities. Using evolution assays and deep sequencing techniques I aim to study (i) the evolution of CRISPR-Cas-mediated immunity in a complex MGE community (i.e. multiple phages and plasmids), and (ii) determine the associated co-evolutionary dynamics. The proposed research is highly multidisciplinary and will perfectly complement my background in biochemistry and molecular biology. It also allows me to establish collaborations with academic and industrial partners to realize applications in dairy industry and phage therapy. The project will be pivotal for my personal development to become an independent researcher and offers me the unique opportunity to work in one of the most prominent microbial ecology and evolution laboratories worldwide, based at the Biosciences Department at the University of Exeter. Biosciences is a leading institute in evolutionary biology, microbiology and ecology that provides excellent opportunities for academic training and personal career development. I will be exposed to novel ideas and input from renowned researchers belonging to scientific disciplines unrelated to my own background, offering exciting opportunities for knowledge exchange and will have a strong impact on my personal and scientific development. Furthermore, I aim to establish a series of lectures for the general public throughout 2015 (the Year of the Phage) to emphasize the importance of phage research for many aspects of our society, including industry and medicine.", "To": ["2017-12-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["660039"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITAT KONSTANZ"], "EU_Contribution": ["EUR 171 795,60"], "Project_Title": ["Perceiving the intentions of the weakest link: How attributed individual and collective goals impact reactions to low performers in groups"], "Total_Cost": ["EUR 171 795,60"], "Country": ["Germany"], "Project_ACR": ["Goal Attribution in Groups"], "Technology_Description": "Group work has become increasingly important for many tasks and services in organisations, and organisations thus depend on successful team function. The entire group\u2019s performance may depend on the lowest performer (weakest link), but groups\u2019 reactions to low performers are not well understood. We suggest that goal attributions are a neglected but potentially powerful factor: Did the low performer try to outperform others (individual goal) or contribute to the group (collective goal)? In the next step, groups should evaluate whether low performers were trying to succeed (but had insufficient abilities) or were not trying (i.e., had low goal commitment). Failing despite trying will lead to excluding competitive low performers (individual goal) but lead to training cooperative low performers (collective goal). Vice-versa, lack of commitment to the collective goal to cooperate should lead to exclusion, but in attempts to change the individual goal of a competitive low performer (socialisation). These hypotheses will be tested in a series of four experiments to attain the objectives of complementing Dr. Th\u00fcrmer\u2019s skillset in (1) small group theory, (2) small group laboratory experiments, (3) transformative multilevel statistics, and (4) to advance the translational transfer to organizational settings. Publications in leading peer-reviewed scientific journals will disseminate the research results widely. The proposed action will open up the immediate career opportunity to establish his independent research group, will substantially advance his research program, and is a crucial step towards becoming a full professor in Germany. Acquired start-up funding enables extensive pre-testing and will ensure the success of this action. This trans-disciplinary research project will contribute to motivation science, small group research, and organizational science and the findings will help European organisations that rely on group work to improve team functioning.", "To": ["2018-08-31, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["703042"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITY OF GLOUCESTERSHIRE"], "EU_Contribution": ["EUR 162 879"], "Project_Title": ["Situated Learning Opportunities fostered by ICT applications in Alternative Agro-Food Networks"], "Total_Cost": ["EUR 162 879"], "Country": ["United Kingdom"], "Project_ACR": ["SOFIA"], "Technology_Description": "The training-through-research project SOFIA - Situated Learning Opportunities fostered by ICT applications in Alternative Agro-Food Networks- aims at enhancing the researcher potential to make broad his horizons and support his career development. In the light of his research objectives he will acquire new knowledge and transfer that one previously developed to the host organization The SOFIA project will allow the ER to became a key facilitator of multidisciplinary research and innovation teams, applying his interdisciplinary competences in service design for innovation, thus ensuring an independent position to the researcher and his future employability in the academic and/or non-academic context. The research SOFIA aims to analyze innovative organizational models and explore the value of the use of ICT tools (e.g. ubiquitous mobile services) to increase Situated Learning Opportunities (SLOs) in an Alternative Agro-Food Networks (AAFNs), through two methodologies i.e multi-case study analysis of local food systems and rural areas and a web-survey of ICT tools for AAFN. The expected impact of the research is to define a set of reproducible methodologies, models, tools and technologies that can improve the competitiveness of a selected area, leveraging its potential in terms of materials and intangible resources. In addition, the study will aim to analyze ICT tools supporting the information flows management both for decision making and for operational processes in the identified collaborative networks.", "To": ["2018-01-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["702884"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["TECHNISCHE UNIVERSITAET GRAZ", "UNIWERSYTET WARMINSKO MAZURSKI W OLSZTYNIE", "UNIVERZA V MARIBORU", "UMEA UNIVERSITET", "MEDIZINISCHE UNIVERSITAT GRAZ"], "EU_Contribution": ["EUR 2 463 975"], "Project_Title": ["Contrast by Quadrupole Enhanced Relaxation"], "Total_Cost": ["EUR 2 463 975"], "Country": ["Austria", "Poland", "Slovenia", "Sweden", "Austria"], "Project_ACR": ["CONQUER"], "Technology_Description": "The ageing society and demographic change is one of the major challenges which Europe is facing now, and even more so in the future. Mastering this challenge requires radically new diagnostic and therapeutic treatments as key factors in achieving the healthy well-being of European citizens. Molecular imaging (MI) plays a pivotal role in diagnosis, understanding of disease and in the development of effective treatments. ", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-1-2014 - FET-Open research projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["665172"], "Call_for_Proposal": ["H2020-FETOPEN-2014-2015-RIA"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI VERONA"], "EU_Contribution": ["EUR 180 277,20"], "Project_Title": ["The 4th Geneva Convention\u2019s Drafting History as the origin of the Responsibility to Protect (R2P) and Duty to Prevent (D2P)."], "Total_Cost": ["EUR 180 277,20"], "Country": ["Italy"], "Project_ACR": ["REQUE 2"], "Technology_Description": "The objective of this project is to uncover the source materials of current humanitarian norms (Responsibility to Protect and Duty to Prevent) within the first and most important tool of International Humanitarian Law \u2013 the 4th Geneva Convention for the Protection of Civilians (1949). Specifically, this project aims to generate a comprehensive historical and legal account of the drafting process and of the 4th Geneva Convention, as to date, no such comprehensive account exists. The research agenda envisages an innovative Multi factor framework approach, examining alongside the Red Cross archives in Geneva, the important National Archives of the US, France, the UK and Switzerland (the Conventions\u2019 Custodian), who all advocated and pushed for the Convention\u2019s endorsement after WWII. The recent opening of national archives, following the lifting of the 50 year disclosure ban provides unprecedented access to hitherto unpublished materials, which could shed much-needed light upon our comprehension of the Convention\u2019s terms and legal interpretation, based upon the original intentions of the drafters. With the interpretation of this convention deeply contested in both judicial and policy circles, uncovering the original drafting sources of the 4th Geneva Convention\u2019s, could shed much needed light on questions regarding the nature of military occupation, of judicial oversight over armed conflict, and of the attitudes to be attributed to irregular fighting forces and non state actors. Recent events, most notably in the Middle East and North Africa point to an alarming tendency of the erosion of any limits to armed conduct. This process goes hand in hand with the exponential surge in civilian casualties in these armed conflicts. Uncovering the original sources which motivated drafters to limit war \u2013 while accepting its existence as a feature of human nature is all the more timely and relevant today.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["701275"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE UNIVERSITY OF EXETER"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Transgenerational Ecophysiological Responses to Multiple Stressors in a changing Ocean"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["TERMS-Ocean"], "Technology_Description": "Global oceans are currently changing at a faster rate than at any other time over the last 300 million years, exposing marine organisms to multiple environmental stressors, such as climate change and ocean acidification (OA). Coastal marine invertebrates are globally important in terms of the ecosystem services and functions that they provide, hence it is vital to determine whether they can adapt and evolve to cope with these multiple stressors at the rate at which they are occurring. The TERMS-Ocean project will address this key question by determining the role of transgenerational phenotypic plasticity (TPP) in the response of a keystone marine invertebrate to the combined impacts of climate change and OA. TPP examines the potential for phenotypic plasticity in offspring in response to parental stress and has been shown to alleviate physiological responses in single-stressor studies; however there is no evidence to date as to whether TPP can operate when multiple stressors are experienced in combination. Here, a novel common garden experimental design will be employed to examine the transgenerational responses of the sea urchin Paracentrotus lividus to the combined effects of elevated temperature and OA in order to assess whether TPP plays a role in alleviating the effects of these stressors when experienced in combination. This project will be pivotal for my personal development to become an independent researcher and offers me the unique opportunity to work in a top 10 Russel Group University with a global reputation for excellence in environmental and climate change research. Exeter Biosciences is a leading institute in environmental biology and ecology and provides excellent opportunities for academic training and personal career development. A fellowship at Exeter will expose me to novel ideas and input from renowned researchers, offer me exciting opportunities for knowledge exchange, and have a strong impact on my personal and scientific development.", "To": ["2018-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-11-01"], "Project_ID": ["704895"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE UNIVERSITY OF EXETER"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Significant or trivial: Fungi in Polar Ecosystems"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["F-Pole"], "Technology_Description": "Fungi are major components of the Earth's biosphere, playing a pivotal role as decomposers and recyclers of nutrients across different environments. However, fungal diversity and function in marine environments has been poorly studied, leading to a biased picture of fungal distribution. Latest studies indicated a distinct marine fungal diversity, including chytrids which can affect algae and zooplankton communities because of their parasitic lifestyle or function as food source. The project intends to investigate the importance of marine fungi in polar-regions, environments that promote the occurrence of endemism and thus the detection of novel species. WP1 aims to study marine fungal diversity and distribution and to provide novel and unique information on the influence of environmental variables on the biodiversity of fungi in these important and changing environments. Two hypotheses will be tested in this work package: firstly, are the fungi identified representative of 'bona-fide' marine lineages and not land-derived origin? Secondly, do fungi represent a higher diversity in marine polar waters compared to temperate and tropical waters? WP2 aims to elucidate the genes transcribed by polar fungi in these atypical and cold environments. This work will allow me to understand the biological characteristics of these fungi that underpin their diversity and distribution profiles by using comparative meta-transcriptomic analysis of environments rich in polar chytrid lineages. Once both work packages are brought together they will help to fill the gap in our understanding of the marine environment, providing important information on ecology of marine communities. Polar environments are undergoing unprecedented changes, it is therefore crucial to understand important components of the microbial community, specifically fungi. The combination of diversity analysis and reconstruction of biological function will uniquely allow for such progress.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["657141"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["INSTITUTE OF FOOD RESEARCH", "UNIVERSITY OF EAST ANGLIA"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Elucidating how Bifidobacteria shapes the microbiota in response to infant diet."], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["INFANT MICROBIOTA"], "Technology_Description": "After birth we are colonized by a consortium of bacteria that are critical for health. Bifidobacteria represent pioneer members, and reach high levels within the gut microbiota of breast-fed infants. These bacteria are proposed to be critical for establishing \u2018healthy\u2019 microbiota development and immune defense; however the mechanisms remain unknown. We hypothesize that breast-milk metabolism by Bifidobacteria provides microbial-derived metabolic products key to promoting stable colonisation of other members in the microbiota, suggesting a mechanism as to why formula-fed infants have an altered microbiota and associated increased risk to a variety of diseases. This MCSA seeks to elucidate the function of Bifidobacteria with host diet, by developing a model colon ecosystem colonised with defined infant bacterial isolates to identify key bifidobacterial-derived metabolic byproducts that differ between breast milk and formula metabolism using cutting-edge metabolic tracer experiments and [13C]-Bifidobacteria pseudocatenulatum. Aim 2 will determine the genomic and regulatory elements in B. pseudocatenulatum required for adaption/metabolism of breast-milk or infant formula in the model colon via construction of a genome-wide mutant library generated by high through-put transposon mutagenesis. Metabolites identified in aim 1 will be linked to specific bifidobacterial gene function, based on the identity of essential mutants unable to grow in the presence of breast-milk (aim 2). We will also determine how host diet impacts microbiota composition in the model ecosystem, by monitoring microbial diversity by 16S rRNA analysis. Finally, to promote a \u2018healthy\u2019 microbiota, identified breast-milk metabolites will be used to supplement the formula fed model. This research will provide critical insight into the function and mechanism of how infant diet impacts bifidobacteria colonisation, with the potential to identify key bifidobacterial-metabolites that promote life-long health.", "To": ["2017-06-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2015-07-01"], "Project_ID": ["661594"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE UNIVERSITY OF EXETER"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Structure \u2013 Oxidative Stress relationships of metal oxide nanoparticles in the aquatic environment"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SOS-Nano"], "Technology_Description": "The SOS-Nano project will address one of the most pressing cutting edge issues of econanotoxicology at present: to find a structural property of nanoparticles (NPs) to predict their potential toxicity in real aquatic environments, the final sink of released NPs. By using an in vivo natural water exposure system, SOS-Nano will test the suitability of two paradigms, recently demonstrated effective in vitro for ranking the hazard of metal oxide NPs: 1) NPs physical-electrochemical properties for predicting oxidative stress potential, and 2) oxidative stress generation for predicting biological impact. ", "To": ["2017-10-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-11-01"], "Project_ID": ["655134"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE UNIVERSITY OF EXETER", "THE UNIVERSITY OF EXETER"], "EU_Contribution": ["EUR 2 206 205"], "Project_Title": ["Accretion, Winds, and Evolution of Spins and Magnetism of Stars"], "Total_Cost": ["EUR 2 206 205"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["AWESoMeStars"], "Technology_Description": "This project focuses on Sun-like stars, which possess convective envelopes and universally exhibit magnetic activity (in the mass range 0.1 to 1.3 MSun). The rotation of these stars influences their internal structure, energy and chemical transport, and magnetic field generation, as well as their external magnetic activity and environmental interactions. Due to the huge range of timescales, spatial scales, and physics involved, understanding how each of these processes relate to each other and to the long-term evolution remains an enormous challenge in astrophysics. To face this challenge, the AWESoMeStars project will develop a comprehensive, physical picture of the evolution of stellar rotation, magnetic activity, mass loss, and accretion.", "To": ["2021-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-07-01"], "Project_ID": ["682393"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI VERONA"], "EU_Contribution": ["EUR 168 277,20"], "Project_Title": ["DOES IT PROMOTE ECONOMY AND WELL-BEING? THE IMPACT OF TELEWORKING ON ENVIRONMENT AND LABOUR MARKET OUTCOMES"], "Total_Cost": ["EUR 168 277,20"], "Country": ["Italy"], "Project_ACR": ["TELE"], "Technology_Description": "This project examines the telework effects on environment and labour market outcomes. More specifically, the first aim of the project is to analyse the link between job satisfaction, labour productivity and firm performance. The second aim is to examine the effects of teleworking on labour productivity/job satisfaction and environment (e.g. traffic, air pollution). The final aim of this study is to examine how teleworking affects the labour market and housework division between men and women. Two databases are used; the Workplace Employment Relations Survey (WERS) and British Household Panel Survey (BHPS). Various econometric techniques are applied, such as Fixed Effects and Dynamic Generalized Methods of Moments (GMM) models Instrumental Variables (IV) and Generalized Latent Class Ordered Probit Models, Seemingly Unrelated Regressions (SURE) and Three Stage Least Squares (3SLS).", "To": ["2017-05-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-06-01"], "Project_ID": ["652938"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI VERONA", "UNIVERSITA DEGLI STUDI DI VERONA", "POLITECNICO DI MILANO"], "EU_Contribution": ["EUR 1 441 875"], "Project_Title": ["IMPROVING PHOTOSYNTHETIC SOLAR ENERGY CONVERSION IN MICROALGAL CULTURES FOR THE PRODUCTION OF BIOFUELS AND HIGH VALUE PRODUCTS"], "Total_Cost": ["EUR 1 441 875"], "Country": ["Italy", "Italy", "Italy"], "Project_ACR": ["SOLENALGAE"], "Technology_Description": "Solar Energy is the most abundant renewable energy source available for our Planet. Light energy conversion into chemical energy by photosynthetic organisms is indeed the main conversion energy step, which originated high energy containing fossil deposits, now being depleted. By the way, plant or algae biomass may still be used to produce biofuels, as bio-ethanol, bio-diesel and bio-hydrogen. Microalgae exploitation for biofuels production have the considerable advantages of being sustainable and not in competition with food production, since not-arable lands, waste water and industrial gasses can be used for algae cultivation. Considering that only 45% of the sunlight covers the range of wavelengths that can be absorbed and used for photosynthesis, the maximum photosynthetic efficiency achievable in microalgae is 10%. On these bases, a photobioreactor carrying 600 l/m-2 would produce 294 Tons/ha/year of biomass of which 30% to 80%, depending on strain and growth conditions, being oil. However this potential has not been exploited yet, since biomass and biofuels yield on industrial scale obtained up to now were relatively low and with high costs of production. The main limitation encountered for sustained biomass production in microalgae by sunlight conversion is low light use efficiency, reduced from the theoretical value of 10% to 1-3%. This low light use efficiency is mainly due to a combined effect of reduced light penetration to deeper layers in highly pigmented cultures, where light available is almost completely absorbed by the outer layers, and an extremely high (up to 80%) thermal dissipation of the light absorbed. This project aims to investigate the molecular basis for efficient light energy conversion into chemical energy, in order to significantly increase the biomass production in microalgae combining a solid investigation of the principles of light energy conversion with biotechnological engineering of algal strains.", "To": ["2021-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["679814"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["THE UNIVERSITY OF EXETER", "THE UNIVERSITY OF EXETER"], "EU_Contribution": ["EUR 2 212 638,60"], "Project_Title": ["Law, Authority and Learning in Imami Shi'ite Islam"], "Total_Cost": ["EUR 2 212 638,60"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["LAWALISI"], "Technology_Description": "The academic study of Islamic law has, so far, almost exclusively focused on Sunni legal thought. The legal thought and practice of Shi\u2019ite (and other) traditions has been neglected, and this has created a rather skewed account of the history of Islamic law. This project aims to rectify this inadequacy by producing a body of research in which the Imami Shi\u2019ite contribution to Islamic legal history is described, analysed and evaluated. Imami Shi\u2019ites, sometimes termed Twelvers, are the largest branch of Shi\u2019ism today. Imamis form a majority in Iran and Iraq where the major Shi\u2019i centres of legal learning are located.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["695245"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["THE UNIVERSITY OF EXETER", "THE UNIVERSITY OF EXETER"], "EU_Contribution": ["EUR 1 252 067"], "Project_Title": ["Fair and Consistent Border Controls? A Critical, Multi-methodological and Interdisciplinary Study of Asylum Adjudication in Europe"], "Total_Cost": ["EUR 1 252 067"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["ASYFAIR"], "Technology_Description": "\u2018Consistency\u2019 is regularly cited as a desirable attribute of border control, but it has received little critical social scientific attention. This inter-disciplinary project, at the inter-face between critical human geography, border studies and law, will scrutinise the consistency of European asylum adjudication in order to develop richer theoretical understanding of this lynchpin concept. It will move beyond the administrative legal concepts of substantive and procedural consistency by advancing a three-fold conceptualisation of consistency \u2013 as everyday practice, discursive deployment of facts and disciplinary technique. In order to generate productive intellectual tension it will also employ an explicitly antagonistic conceptualisation of the relationship between geography and law that views law as seeking to constrain and systematise lived space. The project will employ an innovative combination of methodologies that will produce unique and rich data sets including quantitative analysis, multi-sited legal ethnography, discourse analysis and interviews, and the findings are likely to be of interest both to academic communities like geographers, legal and border scholars and to policy makers and activists working in border control settings. In 2013 the Common European Asylum System (CEAS) was launched to standardise the procedures of asylum determination. But as yet no sustained multi-methodological assessment of the claims of consistency inherent to the CEAS has been carried out. This project offers not only the opportunity to assess progress towards harmonisation of asylum determination processes in Europe, but will also provide a new conceptual framework with which to approach the dilemmas and risks of inconsistency in an area of law fraught with political controversy and uncertainty around the world. Most fundamentally, the project promises to debunk the myths surrounding the possibility of fair and consistent border controls in Europe and elsewhere.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["677917"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["THE UNIVERSITY OF EXETER", "THE UNIVERSITY OF EXETER"], "EU_Contribution": ["EUR 1 499 997,50"], "Project_Title": ["Ecological and evolutionary constraints on the temperature dependence of the carbon cycle"], "Total_Cost": ["EUR 1 499 997,50"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["TEMPDEP"], "Technology_Description": "The cycling of carbon between the biosphere and the atmosphere is mediated by its transformation and flux through ecosystems. Atmospheric CO2 is fixed by photosynthesis, exchanged between organisms via their interactions, and re-emitted to the atmosphere through the by-products of their metabolism (CO2). These metabolic processes are inherently temperature dependent, and consequently there is potential for elevated rates of respiration (CO2 production) in a warmer world to further accelerate global warming. However, large uncertainties about the magnitude of any response exist, owing to limited understanding of the mechanisms underpinning the temperature dependence of ecosystem metabolism. I approach this problem from a new perspective, by proposing that interactions between evolutionary processes, which influence the frequency and variance of metabolic traits within populations, and ecological interactions between populations, which shape the structure and dynamics of communities, constrain the overall temperature dependence of metabolic fluxes at the ecosystem-level. I will ask: How do differences in thermal responses and the nature of ecological interactions between species influence the temperature response of an ecosystem? What is the rate and magnitude of thermal adaptation? Does coevolution in a community affect thermal adaptation? How do differences in thermal responses and turnover in species composition affect the temperature dependence of ecosystems? I will answer these questions with an array of experiments that recombine microbes isolated from a long-term freshwater warming experiment (+4\u00b0C for 10 years) in communities in the laboratory. This project will break new ground in understanding how patterns and processes at the ecosystem-level emerge from the dynamics of populations and communities over ecological and evolutionary timescales. At the same time, it will contribute substantially to understanding carbon cycle responses to global warming.", "To": ["2021-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["677278"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["THE UNIVERSITY OF EXETER"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["All-organic devices in textiles for wearable electronics"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["E-TEX"], "Technology_Description": "We are surrounded by fabrics, the carpet floors in our homes or offices, the seats in our cars, and obviously all our garments and clothing accessories. There are already examples of smart textiles in garments for monitoring physiological and biomechanical signals. However, the manufacturing schemes for current applications rely mostly on the integration of off-the-shelf electronic components mounted on a textile substrate. Such components are silicon-based, thus unsuitable for applications where flexibility and fault-tolerance are required. ", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["704963"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITAT KONSTANZ", "UNIVERSITAT KONSTANZ"], "EU_Contribution": ["EUR 1 918 600"], "Project_Title": ["Discovery of novel orphan riboswitch ligands"], "Total_Cost": ["EUR 1 918 600"], "Country": ["Germany", "Germany"], "Project_ACR": ["RiboDisc"], "Technology_Description": "Riboswitches are mRNA-based gene-regulatory elements triggered by direct interactions with small molecular ligands. They are exciting targets for novel antibiotic strategies. Many putative riboswitches have been identified using bioinformatics. However, ligand identification is getting more complicated since many motifs are not expected to be involved in simple feedback regulation mechanisms. For such \u201cclassical\u201d riboswitches ligands have been assigned in the past based on testing metabolites selected by educated guesses guided by the associated gene contexts. We are convinced that this approach limits the identification of riboswitches that play regulatory roles in more complex bacterial processes such as virulence, detoxification, communication, and life style adaptations. Within this project, new riboswitch classes will be identified and characterized, paving the way for the development of antibiotics with novel modes of action.", "To": ["2021-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-04-01"], "Project_ID": ["681777"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["THE UNIVERSITY OF EXETER", "THE UNIVERSITY OF EXETER", "ROTHAMSTED RESEARCH LIMITED"], "EU_Contribution": ["EUR 1 975 512"], "Project_Title": ["Understanding and exploiting the insect P450 resistome"], "Total_Cost": ["EUR 1 975 512"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom"], "Project_ACR": ["P450RESIST"], "Technology_Description": "Insect resistance to synthetic insecticides and the anti-herbivore defence chemicals produced by many plants is an ongoing challenge to sustainable pest management while also an exceptional model system to study adaptive evolution. The cytochrome P450s are a superfamily of enzymes that are ubiquitous in nature, and one of the most important enzyme families used by insects to defend themselves against natural and synthetic xenobiotics. Insects have been shown to evolve resistance through quantitative changes in P450 expression or via qualitative changes in P450s that alter metabolic activity. Despite their importance in conferring resistance the variety of regulatory changes that modulate P450 expression in resistant insects and their relative frequency/impact is not fully understood. Furthermore, although qualitative changes in insect P450s associated with resistance are relatively rare they represent a unique opportunity to characterise insecticide/toxin binding and identify the critical structure/function determinants of the P450/insect toxin interaction.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2016-01-01"], "Project_ID": ["646625"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["QUEEN MARY UNIVERSITY OF LONDON"], "EU_Contribution": ["EUR 251 857,80"], "Project_Title": ["Legitimacy, Sovereignty and the Public Sphere"], "Total_Cost": ["EUR 251 857,80"], "Country": ["United Kingdom"], "Project_ACR": ["Legitimacy"], "Technology_Description": "The goal of the research is to redefine the interrelations between the concepts of legitimacy, sovereignty, the public sphere and democracy in order to develop a conception of a more inclusive and participatory public sphere.", "To": ["2020-02-29, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-03-01"], "Project_ID": ["704479"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE UNIVERSITY OF EDINBURGH", "THE UNIVERSITY OF EDINBURGH", "THE UNIVERSITY OF EXETER"], "EU_Contribution": ["EUR 1 550 235"], "Project_Title": ["Evolutionary genetics of guppy sex chromosomes"], "Total_Cost": ["EUR 1 550 235"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom"], "Project_ACR": ["GUPPYSEX"], "Technology_Description": "I propose an integrated programme of molecular genetic studies to fill fundamental gaps in our knowledge of sex chromosome evolution. Specifically, I will use a fish, the guppy (Poecilia reticulata), to test the sexual antagonism (SA) hypothesis of sex chromosome evolution, which is plausible, but lacks direct evidence. SA mutations (that benefit one sex but lower fitness of the other) are proposed to arise in a partially sex-linked (pseudo-autosomal region, or PAR) gene, and establish polymorphisms. To reduce the conflict between the sexes, suppressed recombination between X and Y chromosomes then evolves (unless sex-specific expression evolves first). The guppy is ideal for studying this hypothesis because SA polymorphisms are well documented: male coloration phenotypes make males attractive to females, but also make them conspicuous to predators (while females gain no compensating benefit). Moreover, guppies have a recombination-suppressed sex-linked region that carries multiple coloration genes, yet is thought to have evolved recently. However, no non-Y-linked coloration factor has yet been mapped, and the genetics is complicated by modifers making some XX individuals male, and by male-specific expression of some phenotypes. I will map coloration genes and identify PAR genes using DNA-based markers to take account of these problems. I will test for the predicted lower coloration allele frequencies in natural populations with high versus low predation rates, and do population genetic analyses to test for closer linkage under high predation. I will also use X-Y sequence divergence to estimate the age of the guppy sex chromosome. The project tests predictions that emerge from well-documented differing selection regimes in natural guppy populations. I have therefore assembled a team of collaborators experienced with guppies who can provide behavioural and ecological genetic expertise to complement the strength of my own group in molecular evolutionary genetics.", "To": ["2020-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-08-01"], "Project_ID": ["695225"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI VERONA", "UNIVERSITA DEGLI STUDI DI VERONA"], "EU_Contribution": ["EUR 2 500 000"], "Project_Title": ["The role of immune cells in Alzheimer's disease"], "Total_Cost": ["EUR 2 500 000"], "Country": ["Italy", "Italy"], "Project_ACR": ["IMMUNOALZHEIMER"], "Technology_Description": "\"Alzheimer\u2019s disease is the most common form of dementia affecting more than 35 million people worldwide and its prevalence is projected to nearly double every 20 years with tremendous social and economical impact on the society. There is no cure for Alzheimer's disease and current drugs only temporarily improve disease symptoms. ", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["695714"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["UNIVERSITAT KONSTANZ", "UNIVERSITAT KONSTANZ"], "EU_Contribution": ["EUR 1 497 000"], "Project_Title": ["Artificial Natural Products System Synthesis"], "Total_Cost": ["EUR 1 497 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["ANaPSyS"], "Technology_Description": "\"Traditionally, natural products are classified into \"natural product families\". Within a family all congeners display specific structure elements, owing to their common biosynthetic pathway. This suggests a bio-inspired or \"collective synthesis\", as has been devised by D: W. MacMillan. However, a biosynthetic pathway is confined to these structure elements, thus limiting synthesis with regard to structure diversification. In this research proposal the applicant exemplarily devises a strategic concept to overcome these limitations, by replacing the dogma of \"retrosynthetic analysis\" with \"structure pattern recognition\". This concept is termed \"Artificial Natural Product Systems Synthesis \u2014 ANaPSyS\", and aims to supersede the current \"logic of chemical synthesis\" as a standard practice in this field.", "To": ["2021-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-04-01"], "Project_ID": ["679418"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["THE UNIVERSITY OF EXETER", "THE UNIVERSITY OF EXETER", "ADDIS ABABA UNIVERSITY", "KATHOLIEKE UNIVERSITEIT LEUVEN"], "EU_Contribution": ["EUR 1 031 105"], "Project_Title": ["Becoming Muslim: Conversion to Islam and Islamisation in Eastern Ethiopia"], "Total_Cost": ["EUR 1 031 105"], "Country": ["United Kingdom", "United Kingdom", "Ethiopia", "Belgium"], "Project_ACR": ["BM"], "Technology_Description": "\"Why do people convert to Islam? The contemporary relevance of this question is immediately apparent. \"Becoming Muslim\" will transform our knowledge about Islamisation processes and contexts through archaeological research in Harar, Eastern Ethiopia, and examine this in comparison to other regions in sub-Saharan Africa via publication and a major conference. Assessing genuine belief is difficult, but the impact of trade, Saints, Sufis and Holy men, proselytisation, benefits gained from Arabic literacy and administration systems, enhanced power, prestige, warfare, and belonging to the larger Muslim community have all been suggested. Equally significant is the context of conversion. Why were certain sub-Saharan African cities key points for conversion to Islam, e.g. Gao and Timbuktu in the Western Sahel, and Harar in Ethiopia? Archaeological engagement with Islamisation processes and contexts of conversion in Africa is variable, and in parts of the continent research is static. This exciting 4-year project explores, for the first time, Islamic conversion and Islamisation through focusing on Harar, the most important living Islamic centre in the Horn of Africa, and its surrounding region.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["694254"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["THE UNIVERSITY OF EXETER", "THE UNIVERSITY OF EXETER", "THE UNIVERSITY OF SUSSEX"], "EU_Contribution": ["EUR 2 424 263"], "Project_Title": ["SHARING A GENOME: CASTE ANTAGONISM AND COADAPTATION IN SOCIAL INSECTS"], "Total_Cost": ["EUR 2 424 263"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom"], "Project_ACR": ["CASTECON"], "Technology_Description": "Eusociality, in which workers sacrifice their own reproduction to rear the offspring of queens, is a major focus of interest in evolutionary biology. A key aim during recent decades has been to understand the conflicts of interest within eusocial groups. In contrast, however, little is known about the underlying genetic architecture. In this proposal, we will use a mixture of field experiments and transcriptomics to address novel questions about the evolutionary dynamics of queen-worker interactions. Borrowing concepts from the field of sexual conflict, we will investigate a new idea: that the productivity of social groups is limited because castes are constrained by inter-caste genetic correlations from simultaneously reaching their optimal (dimorphic) phenotypes. We will also quantify caste dimorphism across an environmental gradient, and investigate the plasticity of dimorphism using transplants and social manipulations. In addition, we will cross-foster individuals between nests to test for coadaptation between queens and workers. And we will test a long-standing hypothesis experimentally for the first time: that queens manipulate worker phenotype in their own interests. ", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["695744"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["ASTON UNIVERSITY", "UNIVERSIDADE DE AVEIRO", "UNIVERSITAET LEIPZIG", "UNIVERSITA DEGLI STUDI DI MILANO", "VIB", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "CENTRO CARDIOLOGICO MONZINO", "INSTITUTO PORTUGUES DO SANGUE E DA TRANSPLANTACAO IP", "MOLOGIC LTD", "THERMO FISHER SCIENTIFIC (BREMEN) GMBH", "CENTRO HOSPITALAR E UNIVERSITARIO DE COIMBRA E.P.E."], "EU_Contribution": ["EUR 3 545 010,72"], "Project_Title": ["MASS Spectrometry TRaining network for Protein Lipid adduct ANalysis"], "Total_Cost": ["EUR 3 545 010,72"], "Country": ["United Kingdom", "Portugal", "Germany", "Italy", "Belgium", "Spain", "Italy", "Portugal", "United Kingdom", "Germany", "Portugal"], "Project_ACR": ["MASSTRPLAN"], "Technology_Description": "MASSTRPLAN will train the next generation of interdisciplinary research leaders in advanced molecular analytical techniques to detect oxidized phospholipids & proteins in biological & clinical samples, evaluate their biochemical roles in inflammation, and translate these findings to develop new diagnostic tools. ", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other"], "From": ["2015-10-01"], "Project_ID": ["675132"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["THE UNIVERSITY OF EXETER", "THE UNIVERSITY OF EXETER", "UNIVERSITA DEGLI STUDI DI MILANO"], "EU_Contribution": ["EUR 1 792 778"], "Project_Title": ["Procedural Tools for Effective Growth (PROTEGO) Patterns, Outcomes and Policy DesignProcedural Tools for Effective Growth: Patterns, Outcomes and policy Design"], "Total_Cost": ["EUR 1 792 778"], "Country": ["United Kingdom", "United Kingdom", "Italy"], "Project_ACR": ["PROTEGO"], "Technology_Description": "PROTEGO arises out of a fundamental claim: procedural regulatory instruments have causal effects on the performance of political systems because they trigger accountability towards different stakeholders. The mix of policy instruments may be functional or dysfunctional, depending on how accountability mechanisms are combined. This project provides a theoretical rationale to capture the accountability effects by adopting an extension of delegation theory that considers multiple stakeholders. The theoretical framework will allow us to identify the key social mechanisms that make bureaucracies internalize the preferences of accountees. We will test the observable implications of the framework on outcomes that are crucial to the performance of political systems, such as trust in government, ease of business, control of corruption, sustainability. Empirically, we will collect, validate and analyze original data across the EU and its 28 Member States for the period 2000-2015, distinguishing between instruments that cover central departmental activity and independent regulatory agencies. The new dataset will cover administrative procedure acts, freedom of information, notice and comment, judicial review, impact assessment, environmental appraisal, and non-financial instruments for public spending accountability. These are the procedural instruments that enfranchise accountees. The bivariate relationship between a single instrument and outcomes explains little \u2013 because it\u2019s the overall ecology or mix of instruments that produces causal effects. These ecologies combine in different sequences and paths associated with the outcome. Hence we will draw on a suitable methodological approach - Qualitative Comparative Analysis (QCA). Causality and diffusion across time will be also explored via event-history analysis and principal component analysis. PROTEGO will contribute to theories of regulation and accountability, and provide a robust operational model of data and analysis.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["694632"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["THE UNIVERSITY OF EXETER", "THE UNIVERSITY OF EXETER"], "EU_Contribution": ["EUR 1 968 392,05"], "Project_Title": ["The Evolution of Competition and Cooperation: how polymorphisms in microbial populations optimise virulence and mediate drug resistance"], "Total_Cost": ["EUR 1 968 392,05"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["MathModExp"], "Technology_Description": "Microbes form intricate communities where multiple strains and species communicate cooperate and compete, they can cause life-threatening diseases and destroy our food sources. Metabolism is key to these interactions, yet the way microbes acquire and utilise nutrients is often overlooked in evolutionary studies of pathogenicity, virulence and antibiotic resistance. I will address this by quantifying how microbial community composition is determined by the metabolism, genetics and physiology of individual players, establishing principles by which microbial composition affects virulence and antimicrobial resistance. ", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["647292"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["THE UNIVERSITY OF EXETER", "THE UNIVERSITY OF EXETER"], "EU_Contribution": ["EUR 1 648 265"], "Project_Title": ["Imaging the Dynamical Imprints of Planet Formation in Protoplanetary Discs"], "Total_Cost": ["EUR 1 648 265"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["ImagePlanetFormDiscs"], "Technology_Description": "The gas and dust discs around young stars are thought to be the birthplace of planetary systems and are a key area to study if further progress is to be made on understanding the history of our solar system and our own origins. Once planets have formed in these discs, they dynamically sculpt their environment, for instance by opening tidally-cleared gaps or triggering spiral arms and disc warps. The late stages of this process are likely observed in the \u201ctransitional\u201d discs, where regions spanning tens of astronomical units (AU) have been cleared. The aim of this project is to image the planet formation signatures both during the transitional disc and the earlier T Tauri or Herbig Ae/Be stars phase, where the protoplanetary bodies are just starting to carve gaps in the optically thick disc. For this purpose, we will employ the latest generation of near-infrared, mid-infrared, and sub-millimeter interferometric instruments that will allow us to trace a wide range of stellocentric radii, disc scale heights, and dust opacities. We will make use of recent revolutionary advancements in infrared detector technology and equip the CHARA/MIRC 6-telescope beam combiner with a low-read noise camera that will significantly increase the sensitivity of this instrument and enable us to image protoplanetary discs with 2.5 times higher resolution and much higher efficiency than ever before. These quick-look imaging capabilities will enable us to trace time-variable structures in the inner few AU and to investigate their relation to the commonly observed photometric and spectroscopic variability. Our interferometric observations in spectral lines aim to detect the accretion signatures of the young protoplanets themselves. Employing sophisticated radiation hydrodynamics simulations we will achieve an unprecedented global view on protoplanetary disc structure and obtain fundamentally new constraints on theoretical models of planet formation, planet-disc interaction, and disc evolution.", "To": ["2020-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-07-01"], "Project_ID": ["639889"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["Institute of Science and Technology Austria"], "EU_Contribution": ["EUR 166 156,80"], "Project_Title": ["Rate of Adaptation in a Changing Environment"], "Total_Cost": ["EUR 166 156,80"], "Country": ["Austria"], "Project_ACR": ["RACE"], "Technology_Description": "For thousands of years, we have been changing the environment that surrounds us to satisfy our needs and to make our life safer, easier and more prosperous. However, we are not alone on this planet and the increasing magnitude of alterations we impose on our environment impacts the biosphere at every level, from bacteria to mammals. Many of these anthropogenic influences may be fatal for those species, leading to extinction and decrease of biodiversity. To avoid that, it is crucial to understand the process of adaptation in the context of a changing environment, and to understand the limits to population persistence.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["704172"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Sanskrit \u015aaiva Intellectuals in the Empire: Innovations, Textual Practices and Religious Interactions in the Late Vijayanagara Period"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SSIIE"], "Technology_Description": "This project entitled \u2018\u2018Sanskrit \u015aaiva Intellectuals in the Empire: Innovations, Textual Practices and Religious Interactions in the Late Vijayanagara period\u2019\u2019 examines the transformative role of Sanskrit \u015aaiva intellectuals in reshaping the religious landscape of South India during the late Vijayanagara period, i.e., from the mid-fifteenth century to the end of the sixteenth century. It is intended to be the first in-depth study of the intellectual history of two influential \u015aaiva schools of philosophical theology\u2015\u015aiv\u0101dvaita Ved\u0101nta and V\u012bra\u015baivism\u2015on the basis of a rigorous philological and contextual analysis of selected Sanskrit and vernacular textual sources as well as epigraphic material. The evidence will be discussed in terms of the schools\u2019 major doctrinal and philosophical positions, textual practices, as well as mutual influences and interactions with other religious groups. The aims of this project are: 1) to assess the impact of Sanskrit \u015aaiva intellectuals on the broader intellectual and religious world of the late Vijayanagara period, and their relation to the Vijayanagara royal court; and 2) to shed new light on the complex relationships between the various religious groups active during the last decades of the empire, in a context of increasing sectarian debates and dramatic socio-cultural transformations. The project will be carried out at the University of Oxford, one of the most renowned centres in Europe for the study of late medieval and early modern Sanskrit intellectual history.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["702470"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI VERONA"], "EU_Contribution": ["EUR 180 277,20"], "Project_Title": ["A computer-aided study of the Luwian (morpho-)syntax"], "Total_Cost": ["EUR 180 277,20"], "Country": ["Italy"], "Project_ACR": ["SLUW"], "Technology_Description": "The present project aims at analysing the morpho-syntactical features of the Luwian language working on the available texts and combining a standard linguistic analysis with the implementation of a statistical analysis of the annotated corpus. By glossing the morpho-syntactical structure of a large selection of both cuneiform and hieroglyphic inscriptions using a protocol derived from and compatible with the Penn Treebank Project and the Leiden Glossing Rules, the research will proceed by isolating, mapping and modelling the regular as well as the anomalous features of the morpho-syntax of one of the most important and still largely unexplored languages of the ancient Anatolian branch of Indo-European. The analysis will also identify and focus on the co-dependant syntactical, morphological, semantic and stylistic phenomena present in the corpus (e.g. syntactic triggering of stylistic features, dislocations, topicalisations). The results of the present research will provide the world of the Indo-European studies with the first comprehensive study ever dedicated to morpho-syntax of the Luwian language.", "To": ["2017-05-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-06-01"], "Project_ID": ["655954"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE UNIVERSITY OF EXETER"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Rivers as leak in the terrestrial C sink"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["C-LEAK"], "Technology_Description": "Lateral displacement of carbon (C) from soils across inland waters towards the ocean has been intensified due to anthropogenic perturbations and has significant influence on the anthropogenic C budget and the terrestrial C sink. However, Earth System Models (ESM) which are used to simulate the terrestrial C sink at global scale still ignore these lateral fluxes.", "To": ["2018-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-07-01"], "Project_ID": ["703813"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE UNIVERSITY OF EXETER"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["People under Pressure: Settlement Abandonment and Human Responses to Environmental and Socio-Economic Stress during the Medieval and Post-Medieval Periods"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ABANDONMENT"], "Technology_Description": "The ABANDONMENT project explores the pan-European phenomenon of settlement desertion and shrinkage, which occurred especially during the 14th and 17th centuries. Despite considerable attention being paid to this particularly rich aspect of archaeological records (within several disciplines), the process of abandonment still remains poorly understood. The project aims to explore how rural communities and the settlements they lived in responded to socio-economic and environmental stress. The specific objectives are: (a) to determine the processes of settlement shrinkage and abandonment across England; (b) to contextualise changes in settlement patterns within wider transformations of land-use within distinct regions in the longue dur\u00e9e perspective; (c) to explore the cultural and environmental context of settlement evolution (and extinction) across northern and central Europe to determine the impact of these factors on communities. ", "To": ["2017-12-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["656650"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["SMARTLY: NATIVES OF SMART LIVING SRL", "SMARTLY: NATIVES OF SMART LIVING SRL", "UNIVERSITA DEGLI STUDI DELL'AQUILA"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["MobIle health-Care system for monitoring toxicity and symptoms in cAncer patients ReceivingdiseasE-oriented therapy"], "Total_Cost": ["EUR 150 000"], "Country": ["Italy", "Italy", "Italy"], "Project_ACR": ["iCARE"], "Technology_Description": "The project aims at developing a pre-commercial solution, till preparing its entrance to the market, of a new cost-effective mobile system for technology-aided home treatment with oral drugs in cancer patients. This project stems from the ERC Starting Grant VISION, which demonstrated the effectiveness of model-driven approaches for adaptive context-aware resource configuration in internetworking smart objects and wireless multimedia sensor networks. Pervasiveness and easiness of usage that internetworking smart objects may offer to cancer patients in their everyday life, constitute the baseline of the iCARE system. ", "To": ["2017-11-30, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2015 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Italy"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["693680"], "Call_for_Proposal": ["ERC-2015-PoC"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI VERONA", "UNIVERSITA DEGLI STUDI DI VERONA"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Immunomodulatory effects of sustained pantethine release in inflammatory diseases"], "Total_Cost": ["EUR 150 000"], "Country": ["Italy", "Italy"], "Project_ACR": ["IMPEDE"], "Technology_Description": "Auto-immune diseases such as multiple sclerosis (MS) and rheumatoid arthritis (RA) and inflammation-associated brain diseases including Alzheimer's disease (AD) globally make up a \u20ac45B market and cost society close to \u20ac648B. The huge number of patients with these diseases causes an enormous socioeconomic burden. Currently, MS, AD and RA affect 120M people worldwide. There is no cure for AD and treatments for autoimmune diseases are not fully effective and reducing the inflammatory component in these diseases is a key strategy.", "To": ["2017-07-31, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2015 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-02-01"], "Project_ID": ["693606"], "Call_for_Proposal": ["ERC-2015-PoC"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA", "THE UNIVERSITY OF EXETER", "ITA-SUOMEN YLIOPISTO", "HASKOLI ISLANDS", "CONSIGLIO NAZIONALE DELLE RICERCHE"], "EU_Contribution": ["EUR 1 003 500"], "Project_Title": ["Collective Excitations in Advanced Nanostructures"], "Total_Cost": ["EUR 1 003 500"], "Country": ["Italy", "United Kingdom", "Finland", "Iceland", "Italy"], "Project_ACR": ["CoExAN"], "Technology_Description": "This project aims to develop, fabricate, theoretically and experimentally study carbon based nano-circuits which are able to generate, detect and process broadband electromagnetic (EM) signals. The carbon nanoscale EM sources can be based, in particular, on Cherenkov radiation emerging when electrons move inside carbon nanotubes (CNTs) or between spatially separated graphene sheets. The frequency of the Cherenkov radiation depends on the CNT radius and chirality or on the distance between graphene sheets. The performance of carbon EM nano-emitters is determined by the electron momentum relaxation time, which can be determined by measuring the generated THz and microwave fields. The frequency of the emitted EM radiation can be tuned by acoustic waves that provide distributed feedback for the EM wave. As well, the effects originating from strong coupling between material excitations in carbon-based structures and confined optical modes of microcavities will be investigated. The formation of polariton modes and their collective properties will be analyzed theoretically. Another set of problems to be considered in the proposed research is associated with the quantum mechanics and quantum optics of carbon-based nanostructures. We will look at excitonic and plasmonic collective effects in CNTs (especially narrow-band quasi-metallic ones, where excitonic effects are largely overlooked) and in few-layer planar Weyl materials such as graphene, silicene and germanene. We will also study collective photonics phenomena stemming from the quantum nature of light and look at sophisticated arrangements of carbon-based and other nanostructures in arrays or placing them in microcavities, thus utilizing the significant expertise of some of the participating groups in quantum optics aiming eventually at a design and feasibility study of novel advance-nanostructure-based optoelectronic devices including microwave, terahertz and light generators, detectors and frequency modulators.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2015-10-01"], "Project_ID": ["644076"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOMATERIALES- CIC biomaGUNE", "AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH", "UNIVERSITAET LEIPZIG", "UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6", "UNIVERSITY OF MICHIGAN THE REGENTS OF THE UNIVERSITY OF MICHIGAN", "Yerevan State University", "COMISION NACIONAL DE ENERGIA ATOMICA", "CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TECNICAS (CONICET)", "UNIVERSIDAD NACIONAL DE GENERAL SAN MARTIN"], "EU_Contribution": ["EUR 1 219 500"], "Project_Title": ["Hybrid Drug Delivery Systems upon Mesoporous Materials, Self Assembled Therapeutics and Virosomes"], "Total_Cost": ["EUR 1 219 500"], "Country": ["Spain", "Austria", "Germany", "France", "United States", "Armenia", "Argentina", "Argentina", "Argentina"], "Project_ACR": ["HYMADE"], "Technology_Description": "HYMADE focuses on the development of capsules and engineered colloidal particles for drug delivery combining mesoporous colloids, the Layer by Layer (LbL) technique and virosomes. The capsules and particles have potential applications in cancer and inflammatory diseases such as rheumatoid arthritis and uveitis. ", "To": ["2019-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2015-02-01"], "Project_ID": ["645686"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA", "GOETEBORGS UNIVERSITET", "Xtal Concepts GmbH", "INSTALLATION EUROPEENNE DE RAYONNEMENT SYNCHROTRON", "UNIVERSITAET HAMBURG", "LUNDS UNIVERSITET", "MOLIROM SRL", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "ASTRAZENECA AB"], "EU_Contribution": ["EUR 2 331 284,76"], "Project_Title": ["Advanced XFEL and Synchrotron based Probes of Protein Structure and Dynamics"], "Total_Cost": ["EUR 2 331 284,76"], "Country": ["Italy", "Sweden", "Germany", "France", "Germany", "Sweden", "Italy", "France", "Sweden"], "Project_ACR": ["X-probe"], "Technology_Description": "This cross-disciplinary Marie Curie Innovative Training Network builds upon the transformative opportunities created by existing X-ray sources and new sources soon to be operative in Europe. These opportunities include using ultrafast X-ray sources to extract time-dependent structural information from proteins; and revolutionary possibilities created by X-ray Free Electron Laser radiation for an entirely new regime of pre-damage serial femtosecond crystallography. No lag should exist between building new sources and training the next generation of scientists well versed in using these facilities. Our research training will yield new scientific insights on fundamental properties of protein structure and dynamics: one of the most challenging problems in structural biology; and technological advancements in diverse fields from pharmacology to nanotechnology. ", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["637295"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON", "UNIVERSITAT POLITECNICA DE CATALUNYA", "WEST AQUILA SRL", "ADAPT IT AE", "UNIVERSITA DEGLI STUDI DELL'AQUILA", "IQUADRAT INFORMATICA SL", "ADAPTERA TECHNOLOGIKES LYSEIS VELTISTOPIISIS EFARMOGON YPODOMON PLIROFORIKES KAI TILEPIKINONION MONOPROSPI IKE"], "EU_Contribution": ["EUR 1 080 000"], "Project_Title": ["User-centric Middleware Architecture for Advanced Service Provisioning in Future Networks"], "Total_Cost": ["EUR 1 080 000"], "Country": ["Greece", "Spain", "Italy", "Greece", "Italy", "Spain", "Greece"], "Project_ACR": ["CASPER"], "Technology_Description": "The current paradigm in service provisioning to future communication networks lacks thorough end-to-end interpretation from the quality viewpoint, while the end-users\u2019/customers\u2019 profiles and preferences are mostly not taken into account. The subjective perception of a provided service, known as Quality of Experience (QoE), is one of the most important factors for a user\u2019s decision on retaining the service or giving it up, and the key parameter for enabling advanced customer experience management (CEM). The main objective of CASPER is to combine academic and industrial forces towards leveraging the expected benefits of QoE exploitation in future networks. In particular, CASPER will exploit the most recent approaches in communication networks, such as the Software Defined Networking (SDN) and the Network Functions Virtualisation (NFV), to design and implement a middleware architecture for QoE-driven service provisioning. The architecture will consist of three interlinked modules, one-to-one mapped to the three instrumental functionalities required for the beneficial exploitation of QoE: i) reliable, secure and passive QoE monitoring, ii) efficient, dynamic and objective QoE estimation, and iii) robust and real-time QoE-driven service management. The three modules will be optimised and released as an integrated solution, in order to accelerate the adoption of QoE-driven network service management. The cornerstone of this effort will be a carefully-planned inter-sectorial secondment programme for Experienced Researchers (ERs) and Early Stage Researchers (ESRs). Under this programme, CASPER is expected to foster the exchange of knowledge and strengthen the collaboration among academia and industry through a bidirectional knowledge-sharing approach, where the academic beneficiaries will contribute by conveying their knowledge in QoE analysis and modelling, while industrial beneficiaries will provide their expertise in service development and software implementation.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Greece"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-01-01"], "Project_ID": ["645393"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["UNIVERSITAET INNSBRUCK", "UNIVERSITAT POLITECNICA DE VALENCIA", "UNIVERSITY COLLEGE LONDON", "\"NATIONAL CENTER FOR SCIENTIFIC RESEARCH \"\"DEMOKRITOS\"\"\"", "TECHNISCHE UNIVERSITAET WIEN", "KANSALLISARKISTO", "UNIVERSITY OF LONDON", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "UNIVERSITAET ROSTOCK", "XEROX", "DIREKTION DER JUSTIZ UND DES INNERN", "UNIVERSITAET LEIPZIG", "DIOZESE PASSAU", "DEMOCRITUS UNIVERSITY OF THRACE"], "EU_Contribution": ["EUR 8 220 714,50"], "Project_Title": ["Recognition and Enrichment of Archival Documents"], "Total_Cost": ["EUR 8 220 716,01"], "Country": ["Austria", "Spain", "United Kingdom", "Greece", "Austria", "Finland", "United Kingdom", "Switzerland", "Germany", "France", "Switzerland", "Germany", "Germany", "Greece"], "Project_ACR": ["READ"], "Technology_Description": "\"The overall objective of READ is to implement a Virtual Research Environment where archivists, humanities scholars, computer scientists and volunteers are collaborating with the ultimate goal of boosting research, innovation, development and usage of cutting edge technology for the automated recognition, transcription, indexing and enrichment of handwritten archival documents. This Virtual Research Environment will not be built from the ground up, but will benefit from research, tools, data and resources generated in multiple national and EU funded research and development projects and provide a basis for sustaining the network and the technology in the future. This ICT based e-infrastructure will address the Societal Challenge mentioned in Europe in a Changing World namely the \"transmission of European cultural heritage\" and the \"uses of the past\" as one of the core requirements of a reflective society. Based on research and innovation enabled by the READ Virtual Research Environment we will be able to explore and access hundreds of kilometres of archival documents via full-text search and therefore be able to open up one of the last hidden treasures of Europe's rich cultural hertitage.\"", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["EINFRA-9-2015 - e-Infrastructures for virtual research environments (VRE)"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["674943"], "Call_for_Proposal": ["H2020-EINFRA-2015-1"]}, -{"Partners": ["CONSIGLIO NAZIONALE DELLE RICERCHE", "GEIE ERCIM", "ENGINEERING - INGEGNERIA INFORMATICA SPA", "ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON", "FOOD AND AGRICULTURE ORGANIZATION OF THE UNITED NATIONS FAO", "International Council for the Exploration of the Sea", "INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT", "FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS", "TRUST-IT SERVICES LIMITED", "OLOKLIROMENA PLIROFORIAKA SISTIMATA", "COMMUNICATION & INFORMATION TECHNOLOGIES EXPERTS ANONYMOS ETAIREIA SYMVOULEFTIKON KAI ANAPTYXIAKON YPIRESION", "COLLECTE LOCALISATION SATELLITES SA", "STIFTELSEN GRID ARENDAL", "ASSOCIATION POLE MER BRETAGNE"], "EU_Contribution": ["EUR 5 295 753,75"], "Project_Title": ["Building Research environments for fostering Innovation, Decision making, Governance and Education to support Blue growth"], "Total_Cost": ["EUR 5 295 753,75"], "Country": ["Italy", "France", "Italy", "Greece", "Italy", "Denmark", "France", "Greece", "United Kingdom", "Greece", "Greece", "France", "Norway", "France"], "Project_ACR": ["BlueBRIDGE"], "Technology_Description": "BlueBRIDGE responds to the Juncker Investment Plan opening funding opportunities for e-Infrastructures, innovating current practices in producing & delivering scientific knowledge advice to competent authorities & enlarges the spectrum of growth opportunities in distinctive Blue Growth areas. ", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["EINFRA-9-2015 - e-Infrastructures for virtual research environments (VRE)"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Research Organisations", "Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other"], "From": ["2015-09-01"], "Project_ID": ["675680"], "Call_for_Proposal": ["H2020-EINFRA-2015-1"]}, -{"Partners": ["UNIWERSYTET IM. ADAMA MICKIEWICZA W POZNANIU", "THE UNIVERSITY OF EXETER", "UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA", "INSTYTUT FIZYKI MOLEKULARNEJ POLSKIEJ AKADEMII NAUK"], "EU_Contribution": ["EUR 697 500"], "Project_Title": ["MagIC \u2013 Magnonics, Interactions and Complexity: a multifunctional aspects of spin wave dynamics"], "Total_Cost": ["EUR 756 000"], "Country": ["Poland", "United Kingdom", "Spain", "Poland"], "Project_ACR": ["MagIC"], "Technology_Description": "The artificial patterning of nanoscale structures provides an excellent opportunity for modifying spectra of their excitations, and therefore for designing materials with unforeseen properties. Newly created materials (photonic, magnonic or plasmonic) serve as promising candidates for technological applications in integrated devices with smart functionalities for optoelectronic applications, nanoscale thermal transport control, charge free storage and manipulation of information. Magnetic materials with periodically modulated properties, magnonic crystals (MCs) offer two main distinctive features from which the technology can benefit. Firstly, MCs facilitate tunable excitation spectra controlled via magnetic field. Secondly, being non-volatile materials they facilitate exploitation of the re-programmable properties. Hence, significant international research effort in MagIC is now devoted to the area of magnonics and its cross disciplinary opportunities with photonics, phononics and electronics. The frontiers of new ideas, pushing the limits of knowledge, will be developed. The most prominent directions of research are the exploration of nonlinear effects in MCs, tailoring effective damping, developing theoretical models of the spin wave scattering in nanoscale, investigating effects of the broken periodicity and fractal structures on magnonic spectra. Moreover, MagIC will exploit still unexplored directions of mutual coexistence of magnonic functionalities with these of photonic, plasmonic or phononic in a single nanostructure. The academic exchange (168 months of visits in 4 years) supplemented with abundant network and outreach activities will aim to continue existing collaboration, establishing new links, supporting multilateral transfer of knowledge and expertise among seven European and Ukraine research teams, striving to advance the aforementioned research fields, development of innovation and career for research and innovation staff members.", "To": ["2019-01-31, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Poland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-02-01"], "Project_ID": ["644348"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["THE UNIVERSITY OF EXETER"], "EU_Contribution": ["EUR 255 349,80"], "Project_Title": ["Ecological and evolutionary forces shaping microbial diversity in freshwater blooms"], "Total_Cost": ["EUR 255 349,80"], "Country": ["United Kingdom"], "Project_ACR": ["MicroEcoEvol"], "Technology_Description": "\"Bacterial communities dominate the living biomass on Earth and contribute significantly to all global cycles of matter and energy. However, due to the high genetic heterogeneity of the ecosystems and their richness in diverse microbial species, our knowledge of bacterial communities remains limited. Therefore, in order to understand any bacterial community's ecology and predict how these communities and their respective ecosystems will respond to environmental changes, we need (i) to identify the different ecologically distinct microbial populations (or \"\"clusters\"\") that compose it, and (ii) to determine the interactions between clusters, and how they evolve. To address these challenging goals, this study will use the model system of Microcystis, the cyanobacterium that is mainly responsible for toxic algal bloom in lakes worldwide. The goal of this project is to (i) determine how (and if) Microcystis is specialized into different ecologically and genetically distinct clusters, (ii) to track how the Microcystis populations (or clusters) respond to environmental changes (pH, temperature, pollution from fertilizer runoff) and biological factors (viruses that prey on bacteria). This will allow us to understand how Microcystis populations change and adapt over time, helping us to predict and prevent harmful blooms. Using a unique multidisciplinary approach mixing ecology and evolution, and combining observations from natural time-courses in lakes, in situ experiments in microcosms within lakes, and in vitro experiments, this project will provide an unprecedented understanding of how changing regimes of natural selection, imposed by environmental and biological factors, shape microbial communities on the scales of populations, genomes and genes. This project will provide major advances in bloom understanding, in prediction by the identification new genetic biomarkers and in prevention by defining the conditions under which phage therapy might be a practical strategy.\"", "To": ["2018-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-06-01"], "Project_ID": ["656647"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["EUROPEAN X-RAY FREE-ELECTRON LASERFACILITY GMBH", "STIFTUNG DEUTSCHES ELEKTRONEN-SYNCHROTRON DESY", "ELETTRA - SINCROTRONE TRIESTE SCPA", "ASSOCIATION INTERNATIONALE EXTREME-LIGHT-INFRASTRUCTURE DELIVERY CONSORTIUM", "INSTALLATION EUROPEENNE DE RAYONNEMENT SYNCHROTRON", "HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF EV", "LUNDS UNIVERSITET", "PAUL SCHERRER INSTITUT"], "EU_Contribution": ["EUR 7 000 000"], "Project_Title": ["European Cluster of Advanced Laser Light Sources"], "Total_Cost": ["EUR 7 466 800"], "Country": ["Germany", "Germany", "Italy", "Belgium", "France", "Germany", "Sweden", "Switzerland"], "Project_ACR": ["EUCALL"], "Technology_Description": "Advanced optical laser light sources and accelerator-based X-ray sources, as well as their technologies, scientific applications, and user communities, have developed independently over more than five decades. Driven by the developments at each optical laser and free-electron laser research infrastructures (RIs) in recent years, the gap between the optical laser and accelerator-driven light sources has diminished significantly. Both communities operate, implement, or plan advanced laser light source RIs, combining high-power optical and high-brightness X-ray light sources operated as dedicated user facilities. Operational and technical problems of these RIs have become very similar, if not identical. In specific cases, joint projects by the two communities have been initiated, but a closer and more structured collaboration of the corresponding communities and light sources is urgently required and shall be developed through this project.", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["INFRADEV-4-2014-2015 - Implementation and operation of cross-cutting services and solutions for clusters of ESFRI and other relevant research infrastructure initiatives"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations", "Other", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2015-10-01"], "Project_ID": ["654220"], "Call_for_Proposal": ["H2020-INFRADEV-1-2014-1"]}, -{"Partners": ["TECHNISCHE UNIVERSITEIT EINDHOVEN", "UNIVERSITAET LEIPZIG", "JANSSEN CILAG SA", "UNIVERSIDAD DE CORDOBA", "THALESNANO NANOTECHNOLOGIAI KUTATO-FEJLESZTO ZRT", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "KATHOLIEKE UNIVERSITEIT LEUVEN"], "EU_Contribution": ["EUR 2 248 434,36"], "Project_Title": ["Accelerating photoredox catalysis in continuous-flow systems"], "Total_Cost": ["EUR 2 248 434,36"], "Country": ["Netherlands", "Germany", "Spain", "Spain", "Hungary", "France", "Belgium"], "Project_ACR": ["Photo4Future"], "Technology_Description": "The use of visible light energy to induce chemical transformations constitutes an interesting and green activation mode of organic molecules. However, implementation of this energy source in organic synthetic methodologies and in the industrial production of fine chemicals has been challenging. The Photo4Future Innovative Training Network establishes a training network with five beneficiaries from academia and five beneficiaries from industry to tackle the challenges associated with photochemistry in a coherent and comprehensive fashion. In total 13 Early Stage Researchers will be recruited within the Photo4Future network. The network will provide them with opportunities to undertake research with the aim to overcome the current limitations towards the applicability and scalability of photochemical transformations. This will be achieved through a rational design of novel photocatalytic methodologies, improved catalytic systems and innovative photoreactors. Furthermore, the ESRs will be trained in the Photo4Future graduate school, covering training in scientific, personal and complementary skills. All the ESRs will perform two secondments, of which at least one is carried out with an industrial partner. Consequently, the ESRs will have improved career prospects and a higher employability. Due to the high degree of industrial participation, the Photo4Future network will provide an innovation-friendly environment where scientific results can grow and become products or services that will benefit European economies.", "To": ["2018-12-31, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2015-01-01"], "Project_ID": ["641861"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["MBN RESEARCH CENTER GGMBH", "UNIVERSITA DEGLI STUDI DI FERRARA", "JOHANNES GUTENBERG-UNIVERSITAT MAINZ", "AARHUS UNIVERSITET", "THE OPEN UNIVERSITY", "UNIVERSITE PAUL SABATIER TOULOUSE III", "INSTALLATION EUROPEENNE DE RAYONNEMENT SYNCHROTRON", "ISTITUTO NAZIONALE DI FISICA NUCLEARE"], "EU_Contribution": ["EUR 693 000"], "Project_Title": ["Periodically bent crystals for crystalline undulators"], "Total_Cost": ["EUR 693 000"], "Country": ["Germany", "Italy", "Germany", "Denmark", "United Kingdom", "France", "France", "Italy"], "Project_ACR": ["PEARL"], "Technology_Description": "The PEARL project aims at advancing the technologies for manufacturing of high quality Periodically Bent Crystals (PBCr). The PBCr developed in the course of this project will be utilised for the construction of novel light sources of high-energy (h\u03bd\u2265102 keV up to GeV range) monochromatic electromagnetic radiation by means of a Crystalline Undulator (CU) [1]. The technological and experimental part of this project will be accompanied by the complimentary advanced theoretical research utilising modern theoretical, computational and modelling methods accomplished with high performance computing techniques. A broad interdisciplinary, international collaboration has been created in the frame of FP7 PIRSES-CUTE project, which was focused on initial experimental tests of the CU idea and the related theory, for review see [1]. This project has been successfully completed in March 2015 and left the matter experimentally validated to a degree that is tantalising, requiring further experimentation. In particular CUTE elucidated the demand on manufacturing PBCrs of an exceptional lattice quality, their experimental characterisation and exposure against the high quality beams of ultra-relativistic electrons and positrons for the observation of the strong coherent effects in the photon emission process. PEARL will focus on solving the whole complex of the important technological, experimental and theoretical problems aiming to achieve the major breakthrough in this important research area. The PEARL international collaboration is extended with respect to CUTE and involves the new partners with the essential, necessary, complementary expertise and experimental facilities. The PEARL research programme is highly collaborative and requiring numerous exchange visits between the involved laboratories, joint workshops and conferences. Therefore, RISE type of project is the most suitable for strengthening of this very essential, ongoing, international collaborative research.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Germany"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations"], "From": ["2016-01-01"], "Project_ID": ["690991"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY"], "EU_Contribution": ["EUR 182 509,20"], "Project_Title": ["Role of a novel proteasome-associated DUB \u2013 A boon for therapeutics"], "Total_Cost": ["EUR 182 509,20"], "Country": ["Israel"], "Project_ACR": ["DUBs26S"], "Technology_Description": "Clearing-up old or redundant proteins is essential for cells to live; this job is largely done by 26S Proteasome. The multisubunit complex \u2013 26S Proteasome \u2013 is extraordinarily conserved throughout all eukaryotic phyla, in terms of subunit composition and overall structure. However, in preparation of this research proposal, the Researcher found a novel association of 26S proteasome with a clinically important deubiquitinating enzyme (DUB), USP9X. In a subset of proteasome purified from human tissue by the Researcher, USP9X was in fact the major DUB replacing commonly reported enzymes (USP14, UCH-L5). This finding shatters the notion of proteasome as a static, fixed, complex, and opens up the search for expanded spheres of interaction.", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["748804"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["Centrum Fizyki Teoretycznej Polskiej Akademii Nauk"], "EU_Contribution": ["EUR 146 462,40"], "Project_Title": ["Dance of galaxies: testing General Relativity and alternatives using galaxy velocity fields"], "Total_Cost": ["EUR 146 462,40"], "Country": ["Poland"], "Project_ACR": ["GalaxyDance"], "Technology_Description": "We propose to use information encoded in peculiar velocity statistics of galaxies in the Local Universe as well as observed redshift space distortions (RSD) of distant galaxies for rendering new and very precise constraints on the validity of General Relativity (GR) and competing theories of modified gravity (MG) on cosmological and intergalactic scales.", "To": ["2019-09-03, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Poland"], "Activity": ["Research Organisations"], "From": ["2017-09-04"], "Project_ID": ["748525"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE QUEEN'S UNIVERSITY OF BELFAST"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Shakespeare and Indian Cinematic Traditions"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ShakespeareIndia"], "Technology_Description": "Current work on Shakespeare and India has largely ignored the cinematic idiom. Working with acknowledged expert in global Shakespeare, Professor Mark Thornton Burnett (MTB) of Queen\u2019s University Belfast (QUB), experienced researcher, Dr Rosa Mar\u00eda Garc\u00eda Periago (RMGP), will undertake a fellowship that comprehensively examines for the first time the role of Shakespeare in Indian cinemas, with a focus on regionalism, diversity, locality and gender. Rather than simply engaging with \u2018Bollywood\u2019, the fellowship will direct attention to the variety of expressions of Shakespeare in different Indian film industries, languages and diasporic contexts, the majority of which have been critically neglected. Academic outputs include a project website with database, a journal article, and a co-edited volume. Integrally important to the fellowship\u2019s recovery mission is the centrality of women not only as subjects of representation but also as filmmakers and creative practitioners. Bringing together critical and practice-based enquiries, the fellowship includes two secondments with relevant arts organizations. These practice-led elements complement a sustained intercultural engagement programme, including public-facing lectures, a workshop/film festival and an exhibition, of benefit to QUB, the city of Belfast and beyond. The fellowship, then, will produce original research while generating local and international impact and supporting the career development and mobility of the experienced researcher.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["752060"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["DANMARKS TEKNISKE UNIVERSITET", "LUNDS UNIVERSITET", "THE UNIVERSITY OF EXETER", "FORSCHUNGSVERBUND BERLIN EV", "HUMBOLDT-UNIVERSITAET ZU BERLIN", "FUNDACIO INSTITUT DE CIENCIES FOTONIQUES", "NKT PHOTONICS A/S", "RADIANT LIGHT SL"], "EU_Contribution": ["EUR 4 001 129,28"], "Project_Title": ["Infrared sensing made visible: Combining infrared light sources and upconversion sensors for improved sensitivity in medical applications and gas analysis"], "Total_Cost": ["EUR 4 001 129,28"], "Country": ["Denmark", "Sweden", "United Kingdom", "Germany", "Germany", "Spain", "Denmark", "Spain"], "Project_ACR": ["Mid-TECH"], "Technology_Description": "The mid-infrared (mid-IR) wavelength range is an emerging and important new topic for frontier research. Its general importance relates to a multitude of mid-IR industrial and biomedical sensor applications. Chemical finger prints of most complex molecules such as those found in food, tissue or catalytic compounds all have vibrational spectra in the mid-IR, thus identifiable through mid-IR spectroscopy. Incidentally also the fundamental absorption bands of gas molecules are located in the mid-IR enabling novel instrumentation for mid-IR gas spectroscopy at small concentrations relevant for applications like, \u201cleak-tests\u201d or remote sensing of greenhouse gases.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["642661"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Capital Accumulation Through Informal Urbanization in India"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["Urban Informality"], "Technology_Description": "Unauthorized development, informal real estate & housing markets and informal settlements, referred to collectively here as 'informal urbanization' (IU), remain durable, and likely expanding, in much of the global South. IU hampers the implementation of any urban development plan or policy that require land and which require adequate information about land use and above and below ground infrastructure. While much is known about how capital is accumulated and regulated in sectors of the formal economy, much less is known about how this works in the informal economy and very little is known about how this works in IU sectors. This is due to the assumption, influenced by de Soto's work, that the lack of formal property rights leads to 'dead capital', i.e., capital that cannot accumulate. This wisdom must be challenged for if IU is a significant domain of accumulation, then policies and politics by planners and lawmakers for sustainable & inclusive urban development range from inadequacy to lack of fitness for purpose. This Fellowship integrates David Harvey's accumulation theory with Barbara Harriss-White's social structure of accumulation approach to the informal economy to establish a new strand of research. Fieldwork will occur in two municipalities in India where IU is widespread. The aims are: (1) synthesize the theory & evidence of accumulation via IU and its consequences for urban governance and inclusive development more generally (2) qualitatively study & record the phenomena in six cases (3) apply cross-case analysis and (4) disseminate findings via journal articles, policy briefs, city reports, roundtables with respondents, curriculum input & guest lectures. Based at the Contemporary South Asian Studies Program in the School of Interdisciplinary Area Studies at Oxford, with fieldwork in India, the project strengthens my: research networks, research & project management skills and contributes to fields of urban studies, geography & development studies.", "To": ["2019-09-03, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-04"], "Project_ID": ["749814"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITETET I TROMSOE"], "EU_Contribution": ["EUR 208 400,40"], "Project_Title": ["Multiple Perspectives on Grammatical Gender in the Bilingual Lexicon"], "Total_Cost": ["EUR 208 400,40"], "Country": ["Norway"], "Project_ACR": ["GenBiLex"], "Technology_Description": "Grammatical gender represents an important area of research given the difficulty gender assignment and agreement poses to bilinguals at all levels of proficiency. As such, the objective of GenBiLex is to develop a comprehensive proposal of grammatical gender in the bilingual lexicon that includes psycholinguistic, language acquisition and theoretical linguistic approaches. Little previous research has examined the consequences of differences between the L1 and L2 gender systems, either in terms of the number of gender values (e.g. 2 vs 3 values) or the values themselves (e.g. common/neuter vs masculine/feminine). GenBiLex addresses this crucial gap by examining bilinguals with different types of gender systems in order to offer insight into the representation of and interactions between the L1 and L2 gender features in the lexicon and how this is borne out in the use of gender in the L2. ", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["748966"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["QUEEN MARY UNIVERSITY OF LONDON"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Comparative genomics of sugar-eating bats: Implications for the genetics of glucose metabolism and diabetes"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["CHIROGLU"], "Technology_Description": "Diabetes and impaired glucose tolerance are major threats to human health. These conditions are linked to obesity and poor diet but also have major genetic components. To date, most knowledge of the genetics of sugar metabolism and diabetes comes from epidemiological studies of humans and lab studies of mice. However, novel powerful insights might also be obtained by studying novel non-model species that have undergone evolutionary adaptations for subsisting on high sugar diets. Among mammals, bats are unique in their range of dietary specialisations with up to eight lineages having independently evolved nectar-feeding (\u2018nectarivory\u2019). Yet how these bats are able to survive on high sugar diets, and regulate their blood sugar to resist the damaging effects of glucose toxicity, is not understood. To discover the genes and mutations that confer these abilities in bats, we will use state-of-the-art cross-species targeted genome-capture to obtain thousands of orthologous sequences from all nectar-feeding fruit bats and their non-nectar feeding relatives. We will first identify genes showing signatures of molecular adaptation for each key branch associated with the acquisition of nectar feeding. Second, we will compare these sets of genes, and their respective protein-protein interaction networks, to determine whether divergent bats have evolved nectarivory by recruiting the same genes and pathways. Our findings will improve our understanding of how natural selection has driven dietary specialisation in mammals, and will also shed light on whether related metabolic diseases arise via mutations occurring at the same sites, or instead arise from the disruption of more evolutionarily conserved sites that have not been subject to molecular adaptation.", "To": ["2019-06-04, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-05"], "Project_ID": ["753367"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF EXETER"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Multimedia Communication and Processing over Vehicular Cloud Networks for AutonomousDriving"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["MACROSS"], "Technology_Description": "Autonomous driving technologies have recently drawn enormous research attention. It is predicted that autonomous driving will become the most promising form of future Intelligent Transportation Systems (ITS) and will gradually gain market traction in the coming decade. Although several automobile manufacturers have recently demonstrated prototypes, a great number of technical challenges should be addressed in order to reap the full potential of autonomous driving. This project aims to pioneer a framework that leverages innovative multimedia communication and processing technologies for efficient sensor data exchange in order to support autonomous driving application over vehicular cloud networks (VCNs). The project is unique in its ground-breaking integration of two challenging technical aspects over VCNs: multimedia-driven vehicular wireless communications and network-aware adaptive multimedia processing. The interaction and mutual promotion between these two aspects will enable each to design more efficient operational procedure and protocols. ", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["752979"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["Asociacion - Centro de Investigacion Cooperativa en Nanociencias - CIC NANOGUNE"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Proton-Irradiated Ice: Dynamics and Chemistry from First Principles"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["PROIRICE"], "Technology_Description": "Understanding radiation effects on different materials is of paramount importance for many scientific and technological fields like those related to nuclear energy, space industry, laser- and ion-based materials processing and therapeutic applications. The particular case of radiation effects on pure and mixed water ice is very important in Astrochemistry and Prebiotic Chemistry, being water ice present in cosmic dust grains and on the surface of many bodies in the Solar System like asteroids and several satellites (e.g. Europa, Callisto and Ganymede).", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-10-01"], "Project_ID": ["748673"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITETET I TROMSOE"], "EU_Contribution": ["EUR 196 400,40"], "Project_Title": ["Disentangling variation: A crosslinguistic investigation of bilingualism and non-standardization"], "Total_Cost": ["EUR 196 400,40"], "Country": ["Norway"], "Project_ACR": ["DIVA"], "Technology_Description": "This project will investigate the ways in which variation in the linguistic input affects the trajectory of language development and its final outcome. This exploration of language variation and its contributing factors will bring together both the sociolinguistic and the neurocognitive aspects of the human ability to use language, through adopting a cross-linguistic perspective. Acceptability judgment tasks will be the vehicle to test different domains of grammar, such as word-order patterns, adjective orderings, and grammatical illusions, across different linguistic communities in Scandinavia, Cyprus, and Greece. Through examining acceptability judgments in neurotypical adult populations, this project will foster a novel, three-way comparison across (i) monolingual, bilingual, and bilectal speakers, (ii) three domains of grammar, (iii) varying developmental trajectories within the bilingual population, including heritage language learners and L1 attriters. The combination of on-line and off-line measures will shed light on how different domains of grammar are processed by the monolingual and bilingual mind and elucidate whether some or all types of bilingualism confer a cognitive advantage in this processing. Two key objectives of this project are the investigation of both standard and non-standard varieties and the promotion of linguistic diversity. Ultimately, the findings of this project will generate substantive, empirically informed hypotheses about human language and the bilingual mind. Within the present context of increased multilingualism throughout the lifespan these results are likely to achieve a marked scientific impact.", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["746652"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF EXETER"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Female immune function in compensation for polyandry"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["IMMUNFUNC"], "Technology_Description": "The level of polyandry is a key trait influencing population dynamics and inter-sexual interactions of organisms. In nature, females of some species mate only once in their life time, whereas others mate with multiple males. My research aims at understanding why there is so many variation in the level of polyandry. I will tackle this question by focusing on female immune function. Mating can up-/down-regulate immune function, which is likely to inflict fitness costs on females if they mate with multiple males. If the level of polyandry positively correlates with the efficiency of female immune function, immune function may compensate for the costs of multiple mating. To test this hypothesis, I will use 25 isolines of the fruit fly Drosophila pseudoobscura that genetically differ profoundly in their predisposition to polyandry. This unique system will allow me to examine effects of both mating and genetic variation in polyandry on female immune function. This project will complement my current research that to date has focused on specific applied agricultural-pest systems. I have less experience working on explicitly evolutionary-focused questions, so this research programme will provide an additional dimension to my applied research. Prof Wedell is a leading scientist in the field of experimental evolutionary biology, and is the perfect person to expand my horizons into more conceptual and broader ideas. Under her mentoring, I will be able to develop my own research and skills in proposal writing and teaching. The new knowledge, skills and techniques that I will acquire through the project will feed back to my previous work on agricultural pests, which will result in me being able to bridge the gap between model organism and agricultural pest systems. The unique situation will enable me to develop a unique line of research in both evolutionary and applied biology. Ultimately, this Fellowship will put me in an excellent position for my further career.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["746169"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAT KONSTANZ"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Forcing in Contemporary Philosophy of Set Theory"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["Philosophy Forcing"], "Technology_Description": "Forcing is one of the defining techniques of modern set theory. As of late its extensive and deep mathematical results and related foundational questions gained wider attention in the international debate in the philosophy of mathematics. This can be witnessed by the recent development of different research programs in the philosophy of set theory like the Multiverse or Hyperuniverse Program and the formation of new platforms for discussion like the newly founded Set Theoretic Pluralism network. ", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["752211"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI VERONA"], "EU_Contribution": ["EUR 180 277,20"], "Project_Title": ["Currents and Minimizing Networks"], "Total_Cost": ["EUR 180 277,20"], "Country": ["Italy"], "Project_ACR": ["CuMiN"], "Technology_Description": "The core of this project is Geometric Measure Theory and, in particular, currents and their interplay with the", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["752018"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI PADOVA"], "EU_Contribution": ["EUR 180 277,20"], "Project_Title": ["Tackling early school leaving and low school performance through working with students\u2019 representational spaces. The case of 15 years old students in France, Italy and Greece."], "Total_Cost": ["EUR 180 277,20"], "Country": ["Italy"], "Project_ACR": ["RE-mapping"], "Technology_Description": "The project explores the question of early school leaving and low performance two of the five EU headlines for education in the Horizon 2020 agenda, addressing the wider societal challenge of employment and social inclusion of young people. The project argues that the theorization of \u201ccontext\u201d in current state of the art cannot capture the new emerging dynamics caused by globalization and multiple migrations and seeks to establish that students\u2019 \u201crepresentational spaces\u201d operationalized through their imagined geographies operate as an unidentified and powerful hidden curriculum affecting their educational trajectories and career choices. Towards this purpose, a three step field research will be conducted in three EU countries (France, Italy, Greece). First, the representational spaces of 150 15 years old students, of both urban and rural areas, will be explored through questionnaires and visual methodologies. Second, a discourse analysis of the national education policy documents will be conducted to investigate the responsiveness of national policies to the change of scale (EU, global). Third, focus groups and interviews will be conducted in order to investigate if changing students\u2019 representational spaces, involves changes in their attitudes towards school and learning. Correlations will be explored and cross-group comparisons will be made to transcend the existing categorization of the state of the art. These objectives will contribute to the better understanding of students\u2019 educational and life paths under the lens of the current sociopolitical and economic dynamics. ", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["750405"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Catalytic Enantioselective Allene Cycloisomerisation Reactions for Alkaloid Total Synthesis"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["CATRATS"], "Technology_Description": "A new catalytic enantioselective cycloisomerisation reaction for the direct creation of the azabicyclic core of strychnos alkaloids is proposed. Strychnos alkaloids have been the subject of intensive investigation over the last decades. Recently, leuconicines A and B, which are new members of the Strychnos alkaloid family, have been isolated from extracts of the Malaysian plant Leuconotis maingayi. Leuconicines possess significant bioactivity and they potently reverse multidrug resistance in vincristine-resistant leukemia cells. However, further studies into the biological profile of these natural products are hindered due to insufficient quantities being available from the natural source. In order to secure sufficient quantities and fully determine the therapeutic potential of the leuconicines, a new source of these target molecules is required. A new synthetic route which develops and incorporates \u2018state-of-the-art\u2019 methodologies to rapidly forge the extremely complex 6,5,5,6,6,6 hexacyclic ring system and 4 stereocenters, will provide the material. Nevertheless, the synthetic routes toward complex natural products are usually long, contain many individual steps and involve manipulations after each step. For these reasons, new, simple and synthetically efficient organic transformations which reduce the drain of resources are desired. This Fellowship project combines total synthesis, new catalytic enantioselective methodology development, computational calculations and biological evaluation. It has been designed to augment and complement the research and transferable skills sets of the Marie Curie fellow and will greatly enhance his career prospects accordingly. Through the training and the research results arising, the Fellowship will be beneficial to the fellow, the host institution and European science.", "To": ["2019-06-11, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-12"], "Project_ID": ["751281"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF SURREY"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Development of eco-friendly ironmaking processes based onGPU-enhanced DEM-CFD modelling"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["DECRON"], "Technology_Description": "Blast furnaces are widely used in the iron-making industry. The running of blast furnaces consumes 60% energy of whole steel industry and is primarily responsible for the CO2 blueprints in steel plants. As the steel industry is suffering much with the increase iron ore prices and global economy recession in recent years, it has now become a urgent need to adopt innovative approaches to reduce the production cost in iron-making. It is well recognized that the development of eco-friendly steel plants are urgently demanded. DECRON provides a unique and timely opportunity to bring together the fellow\u2019s research experience in the high performance computing, GPU and discrete element modelling (DEM) with the supervisor\u2019s extensive experience in coupled DEM with computational fluid dynamics (DEM-CFD), particle flow, packing and segregation. This will result in the development of novel charging methods for blast furnaces based upon a thorough micro-mechanistic understanding of the process using GPU-enhanced DEM-CFD, and lead to more precision and better controlled charging systems for blast furnaces. DECRON will for the first time devise an indisputable technological innovation and establish feasible strategies to achieve controlled burden distribution in blast furnaces, which will maximise energy efficiency and reduce CO2 emission in iron-making processes.", "To": ["2019-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["747963"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich"], "EU_Contribution": ["EUR 187 419,60"], "Project_Title": ["Multiscale computational modelling for natural hip biomechanics and tribology"], "Total_Cost": ["EUR 187 419,60"], "Country": ["Switzerland"], "Project_ACR": ["MSCHIPBIO"], "Technology_Description": "Hip osteoarthritis (OA) has already affected over 60 million people worldwide, usually causing persistent pain, reduced quality of life and even physical disability to the patients. Currently, the most effective treatment for end-stage of hip OA is total hip replacement (THR). However, current THR surgery is not as successful in younger patients who have expectation of an active life style compared to aging patients. New generation of treatments such as tissue sparing substitution treatment and regenerative treatment for early degenerative disease of the hip joint for these more active patients is urgently required. The new generation of treatments, however, require an in-depth knowledge of the functional biomechanics and tribology of the cartilage in the hip joint. The proposed action, therefore, aims to develop a novel computational method that can simulate the functional performance of natural hip joint for supporting research and development of new generation of cartilage substitution therapies and regenerative interventions for the early degeneration of hip disorders. The action involves an experienced researcher, Dr Xijin Hua, from the University of Leeds in UK visiting the Institute for Biomechanics at Swiss Federal Institute of Technology in Zurich, under the supervision of Professor Stephen Ferguson for 24 months to work on the project \u201cMultiscale computational modelling for natural hip biomechanics and tribology\u201d (MSCHIPBIO). The action also aims to provide a platform for the fellow and the host organisation to share and transfer the knowledge and skills in the field of musculoskeletal biomechanics, advanced finite element simulation methods, computational fluid dynamics and tissue engineering, for the fellow to gain complementary knowledge and skills, and for the host organisation to broaden the research domains in cartilage substitution and regenerative therapies, and to enhance the leading position in the fields of computational biomechanics.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["745426"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Batteries based on Calcium: from electrolyte development to full cell proof-of-concept"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["BATCA"], "Technology_Description": "The development of rechargeable batteries based on multivalent cations as charge carriers holds promise of enhanced energy density when compared to single valent ions such as lithium or sodium. Proof-of-concept has been achieved for magnesium batteries with complex electrolyte compositions but an analogous technology based on calcium ion would hold promise for faster reaction kinetics due to its lower polarizing character and enhanced energy density due to its lower reduction potential. ", "To": ["2019-05-15, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-05-16"], "Project_ID": ["743439"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI VERONA"], "EU_Contribution": ["EUR 180 277,20"], "Project_Title": ["Gluten Epitope Molecularly imprinted polymer Sensor"], "Total_Cost": ["EUR 180 277,20"], "Country": ["Italy"], "Project_ACR": ["GEMS"], "Technology_Description": "Introduction-state of art of the problem: The main goal of the present proposal is to devise a chemical sensor capable of gluten detection in food. Gluten is the allergen that triggers autoimmuno reactions in people suffering of celiac disease (CD). CD is an autoimmune disorder, characterized a variety of genetic assets, which is estimated to affect the 1-2 % of the European population with direct costs on the healthcare estimated as 3 bn Euros/year. According to the state of the current knowledge gluten-free diet is mandatory in CD. Food shall contain less than 20 mg/kg gluten of to be considered as \u201cgluten-free\u201d and to be eaten safely. ", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["752438"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF EXETER"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Elucidating continental-scale patterns of bird migration with weather radars"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["MigrationRadar"], "Technology_Description": "Migration is a wide-spread phenomenon which allows animals of many different taxa to take advantage of seasonal variation in resource abundance. Radar is a powerful tool to observe and track migratory flights. In this action I will use the existing European network of weather radars to investigate bird migration behaviour and patterns at the continental-scale in relation to topography, weather and insect migration. A unique aspect of this action is that I will have access not only to bird migration data from weather radars, but also to complementary data from small-scale dedicated biological radars (units specifically designed to monitor bird and insect migration), as well as bird ringing and monitoring data from several key locations (migration hotspots). Weather radars will provide data on bird migration patterns at the continental-scale (along the \u201cWestern European Flyway\u201d); the small-scale biological radars will provide more detailed information on insect and bird migration patterns at specific sites; and the ringing and monitoring data will provide species composition at specific points along the flyway. Together this will give us a unique overview of the flux and behaviour of migratory animals across Europe, something that has never before been possible.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["749224"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["INSTITUTE OF FOOD RESEARCH"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Fermentation And behaviour of carbohydrates in the colon"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["FABCARB"], "Technology_Description": "Irritable bowel syndrome (IBS) is one of the most commonly diagnosed conditions in the EU with a prevalence of 10-15%, and although not fatal, it is associated with significant co-morbidities and societal costs. The causes of IBS are not well understood, although it has been suggested that there are dietary triggers of the disease, in particular fermentable carbohydrates such as resistant starch (RS). It is believed that alterations to the gut microbiota in IBS sufferers\u2019 leads to changes in the mechanism of fermentation of carbohydrates, resulting the symptoms such as abdominal pain, bloating and diarrhoea commonly associated with IBS.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations"], "From": ["2017-04-01"], "Project_ID": ["747438"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF EXETER"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Selection for antimicrobial resistance in a complex community context"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SARCOM"], "Technology_Description": "Increased antibiotic resistance (AMR) in a wide range of human pathogens is a growing public health threat, and the World Health Organization (WHO) forecasts a post-antibiotic era for the 21st century (WHO, 2014). The evolution of AMR in bacteria is determined by both the acquisition of resistance through horizontal gene transfer or chromosomal mutation and by the way resistance affects the competitive ability of a microbe in the presence and absence of antibiotics. ", "To": ["2019-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["751699"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["AALTO-KORKEAKOULUSAATIO"], "EU_Contribution": ["EUR 249 793,20"], "Project_Title": ["Micromechanics-based finite element modeling of sandwich structures"], "Total_Cost": ["EUR 249 793,20"], "Country": ["Finland"], "Project_ACR": ["SANDFECH"], "Technology_Description": "The use of novel steel sandwich panels in ship decks instead of conventional stiffened plates offers more economical and energy-efficient designs through material, space and fuel savings. To analyse the global structural response of a large ship within computational limits, the sandwich panels need to be modeled in an averaged (homogenized) sense without accounting for every small detail. Motivated by this, my objective is to develop simplified theoretical and computational micromechanics-based beam and plate models for sandwich panels that have unidirectional structural cores and flexible joints. The key theoretical modeling idea is to consider periodic panels as discrete lattices which are replaced by energetically equivalent, linear micropolar continuum beam and plate models. Subsequently, finite element models for the substitute-continuum beams and plates are formulated. Contrary to existing methods, the proposed approach includes all the necessary features. First, it fully accounts for flexible (e.g. laser-welded) joints of the panels. Second, the determination of all model parameters is straightforward. Third, the derived models can be easily implemented later in various readily available finite element software. ", "To": ["2020-08-22, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-23"], "Project_ID": ["745770"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["Conscripted Volunteering: An Ethnographic Study of Community Engagement Schemes in the Israeli Military"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["ConscriptedVolunteer"], "Technology_Description": "Militaries increasingly engage their soldiers in activities framed as \u2018community engagement\u2019 or \u2018volunteering\u2019, ranging from facilitating activities for children to delivering food to the needy. \u2018Conscripted volunteering\u2019, as I term this phenomenon, is part of a broader \u2018moralization\u2019 of contemporary society that glorifies \u2018volunteering\u2019 as a prominent route for ethical conduct. Under neoliberalism, \u2018volunteering\u2019 becomes an object of intensified political interest and promotion. While \u2018volunteering\u2019 that is facilitated by militaries can be considered as a means to enhance their public legitimacy, inspired by corporate techniques of reputation management, I propose to analyse it also as a governmentality technique that reinforces the ideological and ethical adherence of soldiers. The proposed research project explores the intensive implementation of \u2018conscripted volunteering\u2019 in the Israeli military, a military which is considered a paradigmatic case in studies of armed forces.", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["751924"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF EXETER"], "EU_Contribution": ["EUR 263 943"], "Project_Title": ["Individual Specialisation in Established Biological Invasions: importance and Ecological Impact"], "Total_Cost": ["EUR 263 943"], "Country": ["United Kingdom"], "Project_ACR": ["ISEBI"], "Technology_Description": "Differences between individuals are the substance on which natural selection acts; and individual variation has been identified in many ecological dimensions including diet, habitat use and other behavioural traits. It is therefore surprising that this variation is rarely considered within an invasion biology framework, particularly given the enormous biological and economic costs imposed by established invasive species \u2013 those introduced by humans that aggressively expand outside their native range. Little is known about how individual traits influence established invasions, to the extent that it has been argued that either bold, highly competitive individuals, or individuals that are cautious and less aggressive, may be successful. The impacts of different individual invader phenotypes as risks for native biota are also largely unknown, yet this knowledge is key for effective management. This project will, for the first time, determine: i) the extent, covariance and persistence of variation in multiple traits (dietary, behavioural and cognitive) in individual invasive rats simultaneously and in the wild; ii) the impact of the fundamental ecological processes of competition and predation on effective trait combinations i.e. individual phenotypes; iii) the consequences of different phenotypes for native biota. With invasion rates continuing to increase globally, this multidisciplinary approach draws upon cutting-edge techniques from behavioural ecology, comparative psychology, conservation and invasion biology. It provides novel empirical tests of theory, examining hypotheses untested in individual invaders or individuals of any species in natural contexts. The results will have important implications for theoretical understanding of natural selection, and will integrate individual and community processes in the study of invasive species. They will also be of major importance for applied conservation management actions addressing a key EU and global problem.", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["747120"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF EXETER"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Experimental Programme Investigating Cumulative Culture"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["EPICC"], "Technology_Description": "Humans exhibit a rich and complex material culture with no equivalent in other animals. The unique human capability to accumulate cultural innovations across time allows us to develop powerful technology and drives technological progress. Despite a growing literature investigating cumulative culture, the underlying processes at play in the accumulation of cultural knowledge remain puzzling. The overarching aims of this proposal are to identify the requirements of human cumulative culture both at the individual and population levels and improve our understanding of factors that affect the pace of cultural accumulation. During the course of this action, we will develop innovative experimental methods to investigate three important and timely lines of research and shed new light on the complex processes that underlie cultural accumulation: 1) Identify the cognitive requirements of innovation production and transmission, 2) Evaluate the interplay between population structure and cultural accumulation, 3) Evaluate the effects of ecological factors on the rate of innovation. This action will use lab experiments from psychology and economics and will bring knowledge from anthropology and biology to help explain why only humans are able to accumulate cultural information across time and why rates of cultural accumulation have varied in our evolutionary past.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["748310"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF EXETER"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Using charcoals as a proxy to estimate energy released from small Impact cratering processes"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ImpChar"], "Technology_Description": "Over the last half a century there has been much debate over the quantities and mechanisms of thermal energy release during impacts of small asteroids such as Tunguska event (Russia) or Kaali craters. This has been caused in a large part by the fact that the existing observational and modelling approaches have focused on large impact craters that generate high temperature/pressure transitions which leave noticeable signatures in the rocks they affect. However, small impacts craters developed in unconsolidated materials have not been thought to leave long lasting traces of the thermal energy released during their formation. Recently however, Losiak et al. (2016) found charcoal buried within ejecta blanket of Kaali Main crater where sedimentological analyses and 14C dating suggest that the charcoal was formed at the same time as the craters within which they were found. Subsequently Losiak identified charcoal in Kaali 2/8, Ilumetsa Small, Ilumetsa Large and the Morasko Main craters, indicating that charcoal is not restricted to a single crater, single impact or single location. Project ImpCHAR will use a novel analysis method that measures the reflectance properties of charcoal, which has been recently shown to relate to the energy that created it. ImpCHAR will use this method to determine the heating regime from which the chars were created. In order to achieve this Project ImpCHAR will experimentally recreate the heating conditions in a laboratory setting in order to determine the most likely mechanism of charcoal formation. This will allow developing a method of unequivocally identifying small impact craters developed in vegetated unconsolidated sediments: up to this point most of those kinds of structures could be identified only based on circumstantial evidence of co-existing crater-like shape and occurrence of meteorites. Additionally, ImpCHAR will critically disentangle debate surrounding the energy release during formation of small impact craters.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["749157"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF EXETER"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["No country for old sperm: male aging, sperm aging, and external stressors as determinants of sperm quality and fertility"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SPERMAGE"], "Technology_Description": "Deterioration in sperm quality with age is a major cause of male infertility. This has particular socio-economic relevance for Europe where fatherhood is increasingly delayed and infertility has reached near epidemic levels, costing the EU \u20ac4 billion per annum. The mechanisms causing, and the full consequences of declining sperm quality with age remain very poorly understood. For example, it is unclear how much of the reduction in sperm quality is due to advanced male age or the time sperm are stored within males reproductive organs, and we do not understand the mechanisms responsible for deteriorating sperm quality with increasing male age. The general aim of this project is to disentangle the effects of male aging and sperm aging on sperm quality, fertility and reproductive fitness using Drosophila melanogaster as a model. We will also test putative mechanisms thought to cause age-related fertility declines and test two possible general pathways through which sperm age. This proposal is a much needed integration of evolutionary ecology and sperm physiology, benefiting from the ideal match of skills and expertise of the Applicant (Tourmente - physiology), and the PI (Hosken - evolution). Since the mechanisms and phenomena studied are conserved across animals, the research proposed has high potential to produce results relevant to fundamental and applied research in human aging and reproductive health and animal breeding. The MSC fellowship will be pivotal for Applicants development toward independent research and offers the unique opportunity to work in one of the most prominent evolutionary ecology groups worldwide. The Biosciences Department at the University of Exeter is world-leading and provides excellent opportunities for the personal career development of the Applicant, who in turn brings novel skills to Exeter that will greatly benefit this group.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["749784"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KAROLINSKA INSTITUTET", "KAROLINSKA INSTITUTET", "KAROLINSKA INSTITUTET INNOVATIONS AB"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Novel viral therapy through targeting DNA repair"], "Total_Cost": ["EUR 150 000"], "Country": ["Sweden", "Sweden", "Sweden"], "Project_ACR": ["NOVITREP"], "Technology_Description": "Natural epidemics and outbreaks of emerging infectious diseases are a growing problem internationally. RNA viruses remain under constant attention due to the recent Zika virus (ZIKV) outbreak with potential causal relationship with microcephaly of newly born babies and Ebola virus (EBOV) and Crimean-Congo hemorrhagic fever virus (CCHFV) causing life threatening hemorrhagic fever, demonstrating how zoonotic viruses pose a major global health concern. There is an ongoing need to discover novel therapies to battle these pathogenic viruses given that no specific therapy exists. Developing new antiviral treatments by targeting host cell proteins needed in the viral life cycle is an emerging strategy to improve therapeutic power and reduce acquired drug resistance. ", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-07-01"], "Project_ID": ["755150"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION", "BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION"], "EU_Contribution": ["EUR 149 375"], "Project_Title": ["High Performance Genomics for Software Defined Infrastructures"], "Total_Cost": ["EUR 149 375"], "Country": ["Spain", "Spain"], "Project_ACR": ["Hi-OMICS"], "Technology_Description": "The Hi-OMICS PoC aims to pave the road to commercialisation of the Hi-OMICS Controller, a Software Defined Infrastructure Controller (SDI) specifically designed to efficiently manage Computational Genomics workloads running on upcoming SDI platforms. ", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-10-01"], "Project_ID": ["768626"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON", "IQUADRAT INFORMATICA SL", "ERICSSON AB", "NESSOS AE OLOKLIROMENON LISEON KAI SISTIMATON PLIROFORIKIS", "NEC EUROPE LTD", "EURECOM", "UNIVERSITY OF YORK", "MTN CYPRUS LIMITED", "FUNDACIO PER A LA UNIVERSITAT OBERTA DE CATALUNYA", "POLITECNICO DI MILANO"], "EU_Contribution": ["EUR 3 813 484,32"], "Project_Title": ["Single Point Of aTtachment communications empowered by cLoud computing and bIG data analytics running on-top of massively distributed and loosely-coupled Heterogeneous mobile data neTworks"], "Total_Cost": ["EUR 3 813 484,32"], "Country": ["Greece", "Spain", "Sweden", "Greece", "United Kingdom", "France", "United Kingdom", "Cyprus", "Spain", "Italy"], "Project_ACR": ["SPOTLIGHT"], "Technology_Description": "To handle the unprecedented demand for mobile data traffic, different vendors, operators and research programmes have aimed to develop radio access technologies (RATs) that boost physical-layer link capacity, utilize millimeter wave radio, or further densify network topology. Notable steps have also been made towards shifting baseband processing from the (currently) ultra dense network edge to a central location where coordinated resource management will be performed. Nonetheless, the today\u2019s mobile network ecosystem includes vastly heterogeneous, evidently overlapping (in coverage) and fully isolated (in operation) attachment points that still handle most of the functions necessary for mobile data communications independently. Aiming to meet and surpass the requirements set for the 5G-and-Beyond mobile data network, in SPOTLIGHT we will create a fully-integrated and multi-disciplinary network of Early Stage Researchers (ESRs) that will analyze, design, and optimize the performance of a disruptive new mobile network architecture: the SPOTLIGHT architecture. This architecture promises to break performance limitations present to the currently loosely inter-connected, resource-fragmented and isolated in operation mobile network ecosystem, by transforming the currently loosely-coupled multitude of heterogeneous and multi-layered RATs to a flat coalition of massively distributed antenna sub-systems that are optimally orchestrated by a cloud-empowered network core. Our primary aim will be to support for the first time self-including yet ultra-reliable radio communications at the edge network. To further reduce response time and enhance network resilience, all functions necessary for mobile communications will be subject of i) massive parallelization in cloud platforms at the network core and ii) big data analysis running on-top of a virtual pool of shared energy, radio, computing and storage resources at the network.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Greece"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["722788"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["DUBLIN INSTITUTE FOR ADVANCED STUDIES", "DUBLIN INSTITUTE FOR ADVANCED STUDIES"], "EU_Contribution": ["EUR 1 853 090"], "Project_Title": ["Ejection Accretion Structures in YSOs (EASY)"], "Total_Cost": ["EUR 1 853 090"], "Country": ["Ireland", "Ireland"], "Project_ACR": ["EASY"], "Technology_Description": "For a number of reasons, in particular their proximity and the abundant range of diagnostics to determine their characteristics, outflows from young stellar objects (YSOs) offer us the best opportunity of discovering how astrophysical jets are generated and the nature of the link between outflows and their accretion disks. Models predict that the jet is initially launched from within 0.1 to a few au of the star and focused on scales at most ten times larger. Thus, even for the nearest star formation region, we need high spatial resolution to image the \u201ccentral engine\u201d and test current models. ", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["743029"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITA DELLA SVIZZERA ITALIANA", "UNIVERSITA DELLA SVIZZERA ITALIANA"], "EU_Contribution": ["EUR 2 500 000"], "Project_Title": ["Recurrent Neural Networks and Related Machines That Learn Algorithms"], "Total_Cost": ["EUR 2 500 000"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["AlgoRNN"], "Technology_Description": "Recurrent neural networks (RNNs) are general parallel-sequential computers. Some learn their programs or weights. Our supervised Long Short-Term Memory (LSTM) RNNs were the first to win pattern recognition contests, and recently enabled best known results in speech and handwriting recognition, machine translation, etc. They are now available to billions of users through the world's most valuable public companies including Google and Apple. Nevertheless, in lots of real-world tasks RNNs do not yet live up to their full potential. Although universal in theory, in practice they fail to learn important types of algorithms. This ERC project will go far beyond today's best RNNs through novel RNN-like systems that address some of the biggest open RNN problems and hottest RNN research topics: (1) How can RNNs learn to control (through internal spotlights of attention) separate large short-memory structures such as sub-networks with fast weights, to improve performance on many natural short-term memory-intensive tasks which are currently hard to learn by RNNs, such as answering detailed questions on recently observed videos? (2) How can such RNN-like systems metalearn entire learning algorithms that outperform the original learning algorithms? (3) How to achieve efficient transfer learning from one RNN-learned set of problem-solving programs to new RNN programs solving new tasks? In other words, how can one RNN-like system actively learn to exploit algorithmic information contained in the programs running on another? We will test our systems existing benchmarks, and create new, more challenging multi-task benchmarks. This will be supported by a rather cheap, GPU-based mini-brain for implementing large RNNs.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["742870"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["THE UNIVERSITY OF EXETER", "THE UNIVERSITY OF EXETER"], "EU_Contribution": ["EUR 1 998 722"], "Project_Title": ["Context, Identity and Choice: Understanding the constraints on women's career decisions"], "Total_Cost": ["EUR 1 998 722"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["CIC"], "Technology_Description": "There has been vast improvement in workplace gender equality, but there remain marked differences in the roles in which women and men work. Explanations for this inequality have focused on the barriers women face. However, as women begin to enter male-dominated roles, a new explanation has arisen: that remaining gender inequality must reflect fundamental differences between women and men, including differences in (a) ambition and desire for power, (b) needs for work-life balance, and (c) willingness to take career risks. Central to this analysis is the assumption that the glass ceiling is broken and thus inequality must be due to women\u2019s active choices. This explanation downplays the fact that social context continues to be a barrier to women\u2019s success and places responsibility for gender inequality on women themselves. Indeed, there has arisen the suggestion that gender equality necessitates women overcoming \u2018internal obstacles\u2019, \u2018leaning-in\u2019 and altering their choices (Sandberg, 2013), rather than challenging the status quo. I argue that diametrically contrasting structural barriers with women\u2019s choices is unhelpful. Instead, I suggest that women\u2019s choices are shaped and constrained by the gendered nature of organisational and social contexts and how women see themselves within these contexts. I propose a programme of research, across 3 integrated streams, that investigates how social and organisational structures define identities and constrain women\u2019s choices in relation to ambition, work-life balance, and career risk-taking. I have four key objectives: (1) to clarify how organisational and social contexts define identity and constrain women\u2019s choices, (2) to use an interdisciplinary, multi-methodological approach, to produce innovative theory and data, (3) to work collaboratively with stakeholders, and (4) to inform practical interventions designed to facilitate the increase of women\u2019s participation in hitherto male-dominated roles.", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["725128"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["THE UNIVERSITY OF EXETER", "THE UNIVERSITY OF EXETER", "STICHTING VU"], "EU_Contribution": ["EUR 1 854 256"], "Project_Title": ["Average - Transaction Costs and Risk Management during the First Globalization (Sixteenth-Eighteenth Centuries)"], "Total_Cost": ["EUR 1 854 256"], "Country": ["United Kingdom", "United Kingdom", "Netherlands"], "Project_ACR": ["AveTransRisk"], "Technology_Description": "This project focuses on the historical analysis of institutions and their impact on economic development through the investigation of a legal instrument \u2013 general average (GA) \u2013 which underpins maritime trade by redistributing damages\u2019 costs across all interested parties. This will be pursued through the comparative investigation of GA in those European countries where substantial data exists: Italy, Spain, England, France and the Low Countries (1500-1800). Average and insurance were both created in the Middle Ages to facilitate trade through the redistribution of risk. Insurance has been widely studied, average \u2013 the expenses which can befall ships and cargoes from the time of their loading aboard until their unloading (due to accidents, jettison, and unexpected costs) \u2013 has been neglected. GA still plays an essential role in the redistribution of transaction costs, and being a form of strictly mutual self-protection, never evolved into a speculative financial instrument as insurance did; it therefore represents an excellent case of long-term effectiveness of a non-market economic phenomenon. Although the principle behind GA was very similar across Europe, in practice there were substantial differences in declaring and adjudicating claims. GA reports provide unparalleled evidence on maritime trade which, analysed quantitatively and quantitatively through a novel interdisciplinary approach, will contribute to the reassessment of the role played by the maritime sector in fostering economic growth during the early modern first globalization, when GA was the object of fierce debates on state jurisdiction and standardization of practice. Today they are regulated by the York-Antwerp Rules (YAR), currently under revision. This timely conjuncture provides plenty of opportunities for active engagement with practitioners, thereby fostering a creative dialogue on GA historical study and its future development to better face the challenges of mature globalization.", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["724544"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["IIGM FOUNDATION", "UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6", "BEATSON INSTITUTE FOR CANCER RESEARCH LBG"], "EU_Contribution": ["EUR 900 000"], "Project_Title": ["New algorithms for inference and optimization from large-scale biological data"], "Total_Cost": ["EUR 900 000"], "Country": ["Italy", "France", "United Kingdom"], "Project_ACR": ["INFERNET"], "Technology_Description": "The tremendous technological advance underlying the ongoing genomic revolution in the life sciences has profoundly transformed biological research over the last 10-15 years. The grand challenge ahead is to leverage experimental progress like high-throughput sequencing by developing effective tools for large scale data-based inference and optimization. The goals of INFERNET rely on the transfer of ideas and methods developed in recent years at the boundary between statistical physics and information theory into the world of quantitative biology. We aim at setting up a consortium characterized by a proven track-record of high-quality research in order to implement a highly integrated program leading from the design of new algorithms to concrete biological applications. The consortium will provide the optimal environment to nurture a generation of researchers that will drive new developments at the forefront of these challenging fields.", "To": ["2021-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2017-03-01"], "Project_ID": ["734439"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["THE UNIVERSITY OF EXETER", "THE UNIVERSITY OF EXETER", "PHILIPPS UNIVERSITAET MARBURG"], "EU_Contribution": ["EUR 1 499 623"], "Project_Title": ["Forms of Law in the Early Modern Persianate World, 17th-19th centuries"], "Total_Cost": ["EUR 1 499 623"], "Country": ["United Kingdom", "United Kingdom", "Germany"], "Project_ACR": ["Lawforms"], "Technology_Description": "This project will study concepts and practices of law across the early modern Persianate world, investigating how this specific cultural milieu structured understanding of law, legal expression and efforts to secure rights and justice. It will do so by focusing on the ordinary users of law, rather than on specialists, and by using legal documents written in Persian and associated languages produced in five major linguistic-cultural zones stretching from the Indian subcontinent to Iran and the northern and western Indian Ocean. Working with the surviving record of everyday transactions (legal deeds); formularies that standardised such legal forms; extant adjudication records and relevant jurisprudential literature, we shall pay particularly close attention to language \u2013 exploring how translation, multi-lingualism, orality and literacy facilitated processes of vernacularisation of Islamic law, and was actuated through the social and material world of writing.", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["714569"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["THE UNIVERSITY OF EXETER", "THE UNIVERSITY OF EXETER"], "EU_Contribution": ["EUR 1 499 462"], "Project_Title": ["The cultural evolution and ecology of institutions: An integrated evolutionary approach to the interrelated rules that regulate human social organization and cooperation"], "Total_Cost": ["EUR 1 499 462"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["EVORULES"], "Technology_Description": "Humans live in groups of huge numbers of genetically unrelated individuals due to culturally-inherited social rules (\u201cinstitutions\u201d) that structure groups and provide solutions to coordination and collective action problems. However, only in certain places have societies developed more \u201cinclusive\u201d institutions (e.g. democratic governance, the rule of law) that enable the majority of the population (not just elites) to participate in economic and political activities. Fundamental questions about the evolution of institutions still remain. This project will go beyond existing research by employing an overarching cultural evolutionary framework to address a number of outstanding issues such as: How do institutions evolve over time?, How do cultural and ecological factors affect how institutions emerge and spread?, Why have certain institutions emerged or been adopted in only a limited number of places? I will apply innovative statistical, computational and theoretical models from biology to formally and rigorously test a range of hypotheses concerning the evolution of institutions. The project has 3 main objectives (O). In O1 I will use phylogenetic methods to infer the entangled evolutionary history of the institutions that groups possess. In O2 I will employ epidemiological and comparative statistical models, to investigate what factors affect the probability of institutions spreading between societies. In O3 I will use computer simulations to examine how ecological and social factors have led to the emergence of institutions for collective action in some parts of the world but not others. The objectives of this project therefore involve both modelling and empirically assessing theories using cross-national and historical data on institutions and other relevant variables. This more integrated approach will create a step-change in our understanding of institutional change and how evolutionary and ecological processes have shaped the world we live in today.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["716212"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["Institute of Mechanics, Bulgarian Academy of Sciences", "CONSIGLIO NAZIONALE DELLE RICERCHE", "NARRANDO SRL", "UNIVERSITE DE NAMUR ASBL", "UNIVERSITA DEGLI STUDI DI SALERNO", "RESEARCH AND DEVELOPMENT OF NANOMATERIALS AND NANOTECHNOLOGY NANO TECHLAB LTD", "ILIA VEKUA SOKHUMI INSTITUTE OF PHYSICS AND TECHNOLOGY"], "EU_Contribution": ["EUR 1 651 500"], "Project_Title": ["Multifunctional Graphene-based Nanocomposites with Robust Electromagnetic and Thermal Properties for 3D-printing Application"], "Total_Cost": ["EUR 1 935 000"], "Country": ["Bulgaria", "Italy", "Italy", "Belgium", "Italy", "Bulgaria", "Georgia"], "Project_ACR": ["Graphene 3D"], "Technology_Description": "Graphene 3D project proposes highly innovative pathway for the development of optimized, multifunctional graphene-based polymer composites and structures with desired properties for specific applications, based on combination of three main approaches: (i) controlled processing and material\u2019s characterization; (ii) robust nanocomposite design; and (iii) modeling/optimization of nanocomposite cellular structures with predefined properties. Graphene 3D methodology will result in two major outcomes: Multifunctional nanocomposite material for 3D printing application, as well as Optimized and experimentally validated, 3D printed nanocomposite cellular structures with tunable electromagnetic, thermal and mechanical properties. To reach the goal, the proposal will pursue the following main objectives: (1) to develop an effective processing technique for graphene-based polymer nanocomposite; (2) to correlate processing variables with final micro and nanostructure features; (3) to obtain highly improved nanocomposite properties (electrical, electromagnetic, mechanical, thermal); (4) to propose robust design tool for optimizing process-structure-property-performance parameters, resulting in optimized nanocomposite formulation for 3D printing application; (5) to design nanocomposite-based cellular structures with optimum configuration (structure, geometry) and tunable multifunctional characteristics in view of predefined performances; (6) to prove the design concept by fabrication and experimental validation of both nanocomposite material and 3D printed cellular structures that achieve unique properties. Project research & innovation ideas will bring up the research results from TRL 1-2 to TRL 3-4, with potential for application specified towards high power electronics. Graphene 3D will create a Joint Laboratory on graphene-polymer research for knowledge share in a multidisciplinary international/inter-sectoral consortium having long-term implication.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Bulgaria"], "Activity": ["Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations"], "From": ["2017-01-01"], "Project_ID": ["734164"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["UNIVERSITAET INNSBRUCK", "UNIVERSITAET INNSBRUCK", "LUDWIG BOLTZMANN GESELLSCHAFT GMBH"], "EU_Contribution": ["EUR 2 421 223,75"], "Project_Title": ["Nova Scientia. Early Modern Scientific Literature and Latin"], "Total_Cost": ["EUR 2 421 223,75"], "Country": ["Austria", "Austria", "Austria"], "Project_ACR": ["NOSCEMUS"], "Technology_Description": "Fundamental changes occurred in the study of nature between the late 15th and 18th centuries, leading to the emergence of modern science as we know it. This process would have been impossible without Latin as the scientific lingua franca of the era, just as today's science is hard to imagine without English. At present, this crucial role of Latin is insufficiently acknowledged, and the hundreds of thousands of scientific texts written in Latin have largely remained neglected. This severely limits the scope of research into the history of early modern science, an otherwise thriving field. ", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2017-10-01"], "Project_ID": ["741374"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF EV", "ANKARA UNIVERSITESI", "AARHUS UNIVERSITET", "CONSORCIO PARA LA CONSTRUCCION EQUIPAMIENTO Y EXPLOTACION DEL LABORATORIO DE LUZ SINCROTRON", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "STIFTUNG DEUTSCHES ELEKTRONEN-SYNCHROTRON DESY", "DIAMOND LIGHT SOURCE LIMITED", "ELETTRA - SINCROTRONE TRIESTE SCPA", "EUROPEAN X-RAY FREE-ELECTRON LASERFACILITY GMBH", "HELMHOLTZ-ZENTRUM BERLIN FUR MATERIALIEN UND ENERGIE GMBH", "ISTITUTO NAZIONALE DI FISICA NUCLEARE", "INSTALLATION EUROPEENNE DE RAYONNEMENT SYNCHROTRON", "KARLSRUHER INSTITUT FUER TECHNOLOGIE", "LUNDS UNIVERSITET", "PAUL SCHERRER INSTITUT", "STICHTING KATHOLIEKE UNIVERSITEIT", "SYNCHROTRON-LIGHT FOR EXPERIMENTAL SCIENCE AND APPLICATIONS IN THE MIDDLE EAST", "Soci\u00e9t\u00e9 civile SYNCHROTRON SOLEIL", "UNIWERSYTET JAGIELLONSKI"], "EU_Contribution": ["EUR 9 997 538,88"], "Project_Title": ["Convenient Access to Light Sources Open to Innovation, Science and to the World"], "Total_Cost": ["EUR 9 997 538,88"], "Country": ["Germany", "Turkey", "Denmark", "Spain", "France", "Germany", "United Kingdom", "Italy", "Germany", "Germany", "Italy", "France", "Germany", "Sweden", "Switzerland", "Netherlands", "Jordan", "France", "Poland"], "Project_ACR": ["CALIPSOplus"], "Technology_Description": "In the present project, CALIPSOplus, the relevant synchrotrons and free electron lasers in Europe and the Middle East join forces to contribute to the completion of ERA and to tackle the new challenges arising from the commitment of the EU to Open science, Open innovation and Open to the world. Integration with respect to user access, support, instrumentation, data analysis and data management is strongly pushed forward by this advanced community, looking back at a long tradition of integrated activities funded under FP6 and FP7, and largely profiting from the experiences already gained. The European Synchrotron and FEL User Organisation will be consolidated and the performance and use of the wayforlight portal as pivotal platform of the light sources community will be boosted. Data management of the different facilities will be harmonised and a data management plan for the CALIPSOplus consortium be defined. Particular focus will be on leveraging scientific excellence in EU-13 countries and on widening the use of light sources by users from these regions. This will be achieved by visits to universities in these countries, by dedicated schools and by an especially set-up Twinning programme. As a pilot action a specific Trans-national Access programme will be offered for users from SMEs, closely related to an awareness raising campaign for light sources use and the role of light sources as customers among local industry around the facilities. ", "To": ["2021-04-30, ongoing project"], "Meta": [""], "Topic_s": ["INFRAIA-01-2016-2017 - Integrating Activities for Advanced Communities"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["730872"], "Call_for_Proposal": ["H2020-INFRAIA-2016-1"]}, -{"Partners": ["THE UNIVERSITY OF LIVERPOOL", "THE UNIVERSITY OF LIVERPOOL"], "EU_Contribution": ["EUR 149 893"], "Project_Title": ["New thermo-regulating paints based on nanoencapsulation of phase-change materials"], "Total_Cost": ["EUR 149 893"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["ENERPAINT"], "Technology_Description": "\"The proposal is focused on the innovation potential of thermo-regulating paints for effective thermal insulation and controlled release/uptake of the thermal energy in buildings. These thermo-regulating paints are based on the energy nanocapsules with encapsulated phase change materials, which are under development in ERC 2014 Consolidator grant No. 647969 \"ENERCAPSULE\", and current commercial paint formulations. The addition of the energy nanocapsules able to store and release heat will provide commercial paints thermo-regulating properties. The advantage of energy nanocapsules in the paint formulations is the isolation of the phase-change heat capacitors from the other components of the paint. This will keep the integrity of the encapsulated phase-change materials during heating/cooling cycles, prevent the interaction between paint matrix and phase-change material and, as a result, significantly increase the durability of the thermo-responsive paints to thousands of heating/cooling cycles.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["767173"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["KARLSRUHER INSTITUT FUER TECHNOLOGIE", "KARLSRUHER INSTITUT FUER TECHNOLOGIE"], "EU_Contribution": ["EUR 149 875"], "Project_Title": ["Scanner for novel chemical reactions"], "Total_Cost": ["EUR 149 875"], "Country": ["Germany", "Germany"], "Project_ACR": ["CHEMREACTIONSCAN"], "Technology_Description": "Funded by the ERC-Starting Grant COMBIPATTERNING, we have developed a novel nanolayer-based synthesis based on patterning different materials with laser radiation in form of a pan-cake spots in array format. Our synthesis robot can do it for many different materials, for >40.000 spots per glass slide, in exactly defined stoichiometries, and for <200 \u20ac costs. The robot uses short laser pulses to transfer <1ng \u201cpunched-out\u201d material per spot from a donor foil to a synthesis slide. Then, the reactants embedded in the nano thin polymer pan-cake spots can mix with each other and thus undergo chemical reactions by heating the synthesis slide. Due to the large progress in MALDI imaging and the fluorescent scanners, the results of the reactions can be analyzed in the same array format. The masses found by MALDI imaging in some spots might help us to identify unknown chemical reactions. We believe that the nanolayer-based synthesis developed by us might be a basis for future chemistry stations linking scientists and accelerating their studies to screen for novel chemical reactions in a high throughput manner. Instead of studying the interaction between reactants in a single test glass, the chemists will just spin-coat their educts on microscope slides and supply them together with a file for desired reactant combinations to the server - chemical reaction scanner. Therefore, we want to verify the innovation potential of the nanolayer-based synthesis that should find a market where a novel synthesis strategy on combining novel building blocks should be developed, especially, in the field of novel bioactive chemicals and fluorophores.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["766695"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["UNIVERSITY OF LEEDS", "UNIVERSITY OF LEEDS"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Low Cost Material for Exhaust Catalysis (LowCat)"], "Total_Cost": ["EUR 150 000"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["LOWCAT"], "Technology_Description": "This project aims to develop a low cost catalyst to replace the Platinum Group Metals (PGMs) that are widely used in automotive exhaust catalysis. The ERC Advanced Grant project CODITA (project number 291332) is an investigation into the impacts of cosmic dust in planetary atmospheres. During the course of the project we have developed a novel laboratory synthesis of cosmic dust particle analogues. The kinetics of CO oxidation on this material were studied in order to model the heterogeneous oxidation of CO to CO2 in the troposphere of Venus, where the temperature ranges from 120 - 440\u00b0C. Noting that the conditions on Venus are strikingly similar to those in a vehicle exhaust, this discovery forms the basis of the LowCat proposal. Preliminary experiments show that NO is readily taken up on LowCat, which is the first step in the NOx reduction process. The implication is that LowCat could be developed into a 3-way catalyst that is significantly less expensive than current PGM catalysts. This discovery presents an exciting commercialisation opportunity, with very significant societal impacts. Moving toward market requires a proof of core science, patenting of the discovery and commercialisation. The 18 month project planned has specified milestones, project deliverables and value proposition. There are four objectives in the proposal: 1) determine the potential of LowCat to catalyse the reduction of NO in the presence of ammonia; 2) engineer the catalyst onto a suitable support monolith; 3) carry out diesel engine exhaust trials; 4) commercialise the discovery through a patent application and engagement with an industrial partner and potential license.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["768101"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["UNIVERSITAT AUTONOMA DE BARCELONA", "UNIVERSITAT AUTONOMA DE BARCELONA"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Application of genomic inversions as diagnostic markers in precision medicine"], "Total_Cost": ["EUR 150 000"], "Country": ["Spain", "Spain"], "Project_ACR": ["IN2DIAG"], "Technology_Description": "Despite the initial high expectations of genome variation studies, only a small proportion of the genetic risk of common and complex diseases has been identified so far. Most of the work has focused on single nucleotide polymorphisms (SNPs) and copy number variants (CNVs). Inversions, on the other hand, are a type of structural variant that affects a large fraction of the human genome and is implicated in phenotypic differences in diverse organisms. However, they have been poorly studied because their specific characteristics make their detection especially challenging and how much they contribute to human diseases is not yet well known. As part of the INVFEST ERC Starting Grant, we have developed a novel high-throughput technique for genotyping multiple human inversions in hundreds of individuals, which opens new opportunities in the characterization of inversion functional effects and their association with diseases. The aim of the IN2DIAG project is to increase the value of this technology as an innovative diagnostic kit for human inversions that could be licensed to an industrial partner for its commercialization. To achieve that, the main goals are: (1) Carry out a proof of principle study of the association of inversions and 10 common diseases and other health-relevant traits to demonstrate the potential applicability of the technology; (2) Extend the current market research of inversion genotyping needs in a clinical setting and strengthen the contacts with potential licensees and end-user companies; and (3) Maintain the current IPR strategy and if necessary expand this protection with additional patents of possible new discoveries. Our project therefore involves a combined approach, strengthening both the scientific and commercial aspects of the technology, to bring to the market a new tool for the analysis of previously unknown genetic variants, helping to fulfill precision medicine promises.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["755027"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["STOCKHOLMS UNIVERSITET", "STOCKHOLMS UNIVERSITET"], "EU_Contribution": ["EUR 2 324 391"], "Project_Title": ["Axions: From Heaven to Earth"], "Total_Cost": ["EUR 2 324 391"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["AXION"], "Technology_Description": "Axions are hypothetical particles whose existence would solve two major problems: the strong P, T problem (a major blemish on the standard model); and the dark matter problem. It is a most important goal to either observe or rule out the existence of a cosmic axion background. It appears that decisive observations may be possible, but only after orchestrating insight from specialities ranging from quantum field theory and astrophysical modeling to ultra-low noise quantum measurement theory. Detailed predictions for the magnitude and structure of the cosmic axion background depend on cosmological and astrophysical modeling, which can be constrained by theoretical insight and numerical simulation. In parallel, we must optimize strategies for extracting accessible signals from that very weakly interacting source.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["742104"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 2 362 230"], "Project_Title": ["Star-Planet-Inner Disk Interactions (SPIDI): unveiling the formation and evolution of inner planetary systems"], "Total_Cost": ["EUR 2 362 230"], "Country": ["France", "France"], "Project_ACR": ["SPIDI"], "Technology_Description": "With more than 2,000 confirmed exoplanets discovered to date, and about 4,000 additional candidates, it is now widely accepted that nearly every star in the Galaxy hosts a planetary system. These systems greatly differs from our Solar System: a vast majority of exoplanets revolves at a distance less than the Earth\u2019s orbit (1 astronomical unit, 1 AU), and many orbit very close to their parent star indeed (<0.1 AU). These inner planets, with an orbital period less than 100 days, are quite diverse, ranging from Earth-like to Jupiter-like. How do they form or migrate close their star is still an open issue. ALMA and VLT/SPHERE recently released spectacular images of circumstellar disks around young stars, which exhibit large-scale structures (>10 AU), including rings, gaps, and spiral arms that presumably are the signposts of planet formation. Yet, as powerful as they are, imaging techniques are yet unable to probe the inner disk region. The goal of the SPIDI project is to investigate the origin and evolution of inner planetary systems. Specifically, we will develop dynamical models of inner planets embedded in the accretion disk of young stars to investigate the physical processes that govern the star-disk-planet interactions from 1 AU down to the stellar surface. From these models, we will then predict the observational signatures of disk-embedded inner planetary systems, and devise and implement observations that will allow us to detect them. This can only be done indirectly through simultaneous time domain photometry, spectroscopy, spectropolarimetry, and interferometry. Combined with current results obtained on larger scales, the SPIDI project will thus yield a synthetic view of nascent planetary systems, down to the inner edge of protoplanetary disks. It will bring clues to the origin of our own inner Solar System, and more generally, address the formation process and ubiquity of inner planetary systems throughout the Galaxy.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["742095"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 149 293"], "Project_Title": ["A Photothermal Lateral Flow Test for Visual Point of Care Detection"], "Total_Cost": ["EUR 149 293"], "Country": ["Spain", "Spain"], "Project_ACR": ["HOTFLOW"], "Technology_Description": "The rapid development of cost-effective and efficient biosensors has had a profound worldwide socioeconomic impact. Advances in the fields of microelectronics, materials science and nanotechnology have been vital to the implementation of enhanced sensing platforms aimed at providing alternatives to traditional analytical methods. Further, current sensing platforms are often slow, unreliable and expensive; in particular, when ultralow concentration detection is required. Although progress in the biosensors field typically focuses on clinical point-of-care diagnosis, a clear demand exists in areas such as food safety regulation, environmental policy, military and the arts, where time, cost, portability and ease-of-use of the device are critical. The grand aim of HOTFLOW is to develop an innovative, rapid, inexpensive, versatile and sensitive thermal transduction biosensor for the ultralow detection and quantification of relevant proteins such as tumoral markers. This novel sensing technology will use detection biomolecules linked to plasmonic gold nanoprisms which serve as thermal transducers by based on a lateral flow immunoassay and a \u201csandwich\u201d recognition strategy with capture biomolecules immobilized on a dual-active nitrocellulose membrane support/thermosensitive paper that subsequently functions as photographic and tracing detection element. Although the ambitious thermal sensing device proposed here will be prototyped using simple analytes, this ERC POC project goes significantly beyond the current state-of-the-art in nanoplasmonics and biosensing by proposing the development and elaboration of an almost universal paper-based thermal sensing device. This technology will be implemented and validated by applying it to a specific problem, gastrointestinal cancer diagnosis.", "To": ["2019-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-08-01"], "Project_ID": ["754609"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["UNIVERSITAT KONSTANZ", "UNIVERSITAT KONSTANZ"], "EU_Contribution": ["EUR 147 000"], "Project_Title": ["Blended Learning Course for Police Students: Death Notification with Responsibility"], "Total_Cost": ["EUR 147 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["DNR"], "Technology_Description": "The aim of the proposed transfer project is to develop the blended learning course \u201eDeath Notification with Responsibility\u201c (DNR) for police officers. In situations of unnatural death (accidents, suicides, terror attacks or other forms of violence), police officers have to deliver a death notification to the family members of the deceased. Unnatural death is the worst possible message to be delivered. It will change the lives of those informed decisively and will remain in their memories forever. The core findings of the ERC project \u201eNarratives of Terror and Disappearance\u201c (NoT-240984) established the devastating social effects of uncertainty caused by non-information and the material absence of bodies in confrontation with violent death. ", "To": ["2018-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["754949"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["Academisch Medisch Centrum bij de Universiteit van Amsterdam", "Academisch Medisch Centrum bij de Universiteit van Amsterdam"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Circulating tumor cells for tailoring BMP targeted therapies"], "Total_Cost": ["EUR 150 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["CTC4BMP"], "Technology_Description": "Gastro-intestinal (GI) cancers, including gastro-esophageal junctional (GEJC), gastric (GC), colorectal (CRC) and pancreatic cancer (PC) are devastating malignancies that annually affect over 2 million persons worldwide and lead to more than 600,000 deaths (Globocan 2012). Given the current trends, the incidence of GI cancer is expected to increase further. Conventional therapies include chemo- and radiation therapy combined with surgery. However, amongst cancer patients, GI cancer patients have one of the poorest outcomes with a 5-year survival ranging from only 60% for CRC to a mere 5% for PC", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["737612"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["DEUTSCHES KREBSFORSCHUNGSZENTRUM", "DEUTSCHES KREBSFORSCHUNGSZENTRUM"], "EU_Contribution": ["EUR 2 006 250"], "Project_Title": ["Detecting, understanding and exploiting intracellular redox signaling relays"], "Total_Cost": ["EUR 2 006 250"], "Country": ["Germany", "Germany"], "Project_ACR": ["Redox Relays"], "Technology_Description": "Redox signaling is a process by which endogenous oxidants, derived from metabolism, reversibly modify particular thiols on particular proteins to change their functional behavior in an adaptive manner. However, the molecular mechanisms of redox signaling remain largely unknown. In particular, specificity and efficiency of redox signaling remain unexplained. The now emerging solution to this conundrum is that redox signaling is mediated and channeled by protein-to-protein redox relay chains that dynamically assemble in the cytosolic, nuclear and mitochondrial compartments. We and others have found that H2O2 signals are relayed through thiol peroxidases to neighboring proteins within supramolecular assemblies. Evidence now suggests that so far we have just glimpsed the \u2018tip of the iceberg\u2019, namely that redox relay chains are ubiquitous and also operate for reactive nitrogen and sulfur species. This project aims to systematically uncover, dissect, monitor and manipulate the redox relay chains that give specificity and efficiency to redox signaling. The basic strategy is to tag all protein-coding genes with genetically encoded reporters which \u2013within the context of the living cell\u2013 sense the transmission of thiol oxidizing equivalents within their sphere of immediate proximity (\u224810 nm). A combination of genetic screening, redox proteomics and transcription profiling will then allow to identify the composition of redox relays, their endogenous target proteins und their functional impact on gene regulation. The knowledge about the composition of redox relays will lead to precision tools for the observation and manipulation of defined redox signaling pathways in vivo. The project is expected to yield fundamental insights into the specific molecular links by which reactive oxygen, nitrogen and sulfur species couple changes in metabolism to cellular and organismal adaptations regulating resilience and healthspan.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-10-01"], "Project_ID": ["742039"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE"], "EU_Contribution": ["EUR 149 875"], "Project_Title": ["Accurate cell signatures for the advancement of personalized medicine"], "Total_Cost": ["EUR 149 875"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["Cellphmed"], "Technology_Description": "Patient/individual specific cells, including induced pluripotent stem (iPS) cells will be crucial in defining tomorrow\u2019s medicine owing to their uses in drug discovery, immunotherapy or cell therapy. These clinical applications require the utmost accurate and reliable identity and purity testing, however, the majority of cells stored worldwide fall short of a sufficient level of characterisation. This project aims at validatating and commercializing an innovative method of diagnostic and quality control for human cells. It is based on our unprecedented ability to measure the expression of millions of uncharted RNA biomarkers called TEs, genetic units that contribute over 50% of the genome but that have been completely disregarded until very recently, mainly due to the challenge imposed by their complex analysis. Our new methodology provides a high-density barcode of cellular identity, opening the door for individual-specific cells to broad applications in biotechnology and medicine alike.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["737562"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 860 962,50"], "Project_Title": ["Fast determination of fatigue properties of materials beyond one billion cycles"], "Total_Cost": ["EUR 1 860 962,50"], "Country": ["France", "France"], "Project_ACR": ["FastMat"], "Technology_Description": "Many mechanical structures are submitted to repeated loadings and can break under stress lower than the ultimate tensile stress. This phenomenon is called the fatigue of materials and can be found in many industrial sectors, such as the transport industry, aeronautic industry and energy production. Fatigue design is thus crucial in engineering and it requires the precise characterization of material behavior under cyclic loadings to ensure the safety and reliability of structures throughout their life. An increase in the life span of a structure or a reduction in the number of maintenance phases leads to an increases in the number of cycles applied to this structure. It is presently common to find mechanical systems subjected to several billion cycles, in what is called the gigacycle fatigue domain. The characterization of the fatigue behavior of materials requires fatigue tests to be conducted until fracture for different stress amplitudes. One problem with this method is the test duration, which becomes excessive and beyond possible, particularly for a very high number of cycles. The goal of FastMat is to develop a new method that reduces considerably the duration of fatigue characterization. This method involves the use of only short interrupted tests coupled with a self-heating measurement to characterize the fatigue behavior for very low stress amplitudes. The scientific objective is to develop simultaneously experimental and numerical tools for the fast determination of fatigue behavior. The experimental approach will be developed to estimate simultaneously the dissipation and the stored energy, which directly reflect fatigue damage. For the numerical approach, discrete dislocation dynamics simulations will be developed to establish links between the fatigue damage associated with the evolution of dislocation structures, the stored energy and the dissipated energy.", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-07-01"], "Project_ID": ["725142"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["ACADEMISCH ZIEKENHUIS LEIDEN", "ACADEMISCH ZIEKENHUIS LEIDEN"], "EU_Contribution": ["EUR 1 999 802,50"], "Project_Title": ["The role of complement in the induction of autoimmunity against post-translationally modified proteins"], "Total_Cost": ["EUR 1 999 802,50"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["AUTOCOMPLEMENT"], "Technology_Description": "In many prevalent autoimmune diseases such as rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) autoantibodies are used as diagnostic and prognostic tools. Several of these autoantibodies target proteins that have been post-translationally modified (PTM). Examples of such modifications are citrullination and carbamylation. The success of B cell-targeted therapies in many auto-antibody positive diseases suggests that B cell mediated auto-immunity is playing a direct pathogenic role. Despite the wealth of information on the clinical associations of these anti-PTM protein antibodies as biomarkers we have currently no insight into why these antibodies are formed.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["724517"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["Institute of Science and Technology Austria", "Institute of Science and Technology Austria"], "EU_Contribution": ["EUR 2 306 862"], "Project_Title": ["Interaction and feedback between cell mechanics and fate specification in vertebrate gastrulation"], "Total_Cost": ["EUR 2 306 862"], "Country": ["Austria", "Austria"], "Project_ACR": ["MECSPEC"], "Technology_Description": "Embryogenesis is achieved by the close interplay between the gene regulatory networks that control cell fate specification and the physical processes by which the embryo takes shape. While each of these systems has been extensively investigated over the past decades, comparably little is yet known about how they functionally interact across different scales of organization within the physiological context of the developing embryo. The central aim of this proposal is to elucidate the fundamental principles underlying the interaction and feedback between cell mechanics and fate specification during vertebrate gastrulation. Using zebrafish as a vertebrate model organism, we will explore how germ layer progenitor cell fate specification affects the physical processes by which the gastrula takes shape, and, vice versa, how alterations in cell/tissue mechanics feed back onto the gene regulatory networks and signals controlling progenitor cell fate specification during gastrulation. To dissect the fundamental mechanisms underlying this crosstalk, we will combine genetic, cell biological and biophysical experimentation with mathematical modeling. We expect that this transdisciplinary approach will provide answers to a central yet unresolved question in developmental biology: how the interplay between cell mechanics, dynamics and fate specification drives embryo morphogenesis and patterning.", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["742573"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 499 192"], "Project_Title": ["Gestures in nonhuman and human primates, a landmark of language in the brain? Searching for the origins of brain specialization for language"], "Total_Cost": ["EUR 1 499 192"], "Country": ["France", "France"], "Project_ACR": ["GESTIMAGE"], "Technology_Description": "Most of language functions are under the left brain control in both left- and right-handers and involve structural asymmetries between the two hemispheres. While this asymmetry was considered as associated with handedness, such a relation has been recently questioned. Considering the strong language/gesture links in humans and the continuities between the gestural system in apes and monkeys and some language properties, we recently suggested the hypothesis of a continuity between language lateralization and asymmetry of communicative gestures in both human and nonhuman primates. Given the phylogenetical proximity between those species, comparative research on brain specialization between a non-linguistic gestural system (i.e., in monkeys) versus a linguistic gestural systems in humans (i.e., sign language in deaf) might help evaluating the gestural continuities with language lateralization in term of manual asymmetries, structural and functional lateralization of the brain. ", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["716931"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["THE UNIVERSITY OF EXETER", "THE UNIVERSITY OF EXETER"], "EU_Contribution": ["EUR 2 447 699"], "Project_Title": ["Photonically fused molecular materials"], "Total_Cost": ["EUR 2 447 699"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["PHOTMAT"], "Technology_Description": "Molecular materials are ubiquitous, encompassing smart phone displays, plastic electronics and the molecular machinery of photosynthesis. Many of these remarkable uses depend on interactions between the molecules. Until now these interactions have been electric in character, and have been dictated by how electric charge is distributed over the molecules. PHOTMAT will transform the world of molecular materials by adding a new ingredient \u2013 photons. I will fuse photons and molecules together to create new hybrid states \u2013 part molecule and part photon \u2013 that are dramatically different from those of the constituent molecules and photons. The idea of coupling molecules with photons is a radical new approach with implications that reach across physics, quantum information, chemistry, materials science, nanotechnology and biology.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["742222"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON", "UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 1 498 069"], "Project_Title": ["Analysing South-South Humanitarian Responses to Displacement from Syria: Views from Lebanon, Jordan and Turkey"], "Total_Cost": ["EUR 1 498 069"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["ASSHURED"], "Technology_Description": "Since 2012, over 4 million people have fled Syria in \u2018the most dramatic humanitarian crisis that we have ever faced\u2019 (UNHCR). By November 2015 there were 1,078,338 refugees from Syria in Lebanon, 630,776 in Jordan and 2,181,293 in Turkey. Humanitarian agencies and donor states from both the global North and the global South have funded and implemented aid programmes, and yet commentators have argued that civil society groups from the global South are the most significant actors supporting refugees in Lebanon, Jordan and Turkey. Whilst they are highly significant responses, however, major gaps in knowledge remain regarding the motivations, nature and implications of Southern-led responses to conflict-induced displacement. This project draws on multi-sited ethnographic and participatory research with refugees from Syria and their aid providers in Lebanon, Jordan and Turkey to critically examine why, how and with what effect actors from the South have responded to the displacement of refugees from Syria. The main research aims are:", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["715582"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["INSTALLATION EUROPEENNE DE RAYONNEMENT SYNCHROTRON", "CONSORCIO PARA LA CONSTRUCCION EQUIPAMIENTO Y EXPLOTACION DEL LABORATORIO DE LUZ SINCROTRON", "THE CYPRUS INSTITUTE", "STIFTUNG DEUTSCHES ELEKTRONEN-SYNCHROTRON DESY", "ELETTRA - SINCROTRONE TRIESTE SCPA", "ISTITUTO NAZIONALE DI FISICA NUCLEARE", "INSTRUCT ACADEMIC SERVICES LIMITED", "SYNCHROTRON-LIGHT FOR EXPERIMENTAL SCIENCE AND APPLICATIONS IN THE MIDDLE EAST", "Soci\u00e9t\u00e9 civile SYNCHROTRON SOLEIL", "EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 957 323,75"], "Project_Title": ["Opening Synchrotron Light for Experimental Science and Applications in the Middle East"], "Total_Cost": ["EUR 2 100 823,75"], "Country": ["France", "Spain", "Cyprus", "Germany", "Italy", "Italy", "United Kingdom", "Jordan", "France", "Switzerland", "France"], "Project_ACR": ["OPEN SESAME"], "Technology_Description": "The OPEN SESAME project will ensure optimal exploitation of the Synchrotron light for Experimental Science and Applications in the Middle East (SESAME) light source. With this aim, OPEN SESAME has three key objectives: ", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["INFRASUPP-01-2016 - Policy and international cooperation measures for research infrastructures"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Other", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Research Organisations", "Research Organisations"], "From": ["2017-01-01"], "Project_ID": ["730943"], "Call_for_Proposal": ["H2020-INFRASUPP-2016-1"]}, -{"Partners": ["UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN", "UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN"], "EU_Contribution": ["EUR 148 805"], "Project_Title": ["Antibiofouling Nanopatterned Electrospun Membranes for Nanofiltration Applications"], "Total_Cost": ["EUR 148 805"], "Country": ["Ireland", "Ireland"], "Project_ACR": ["ANEMONE"], "Technology_Description": "Water-stress in an increasing global problem and solutions such as water recycling and seawater desalination are now becoming a necessary part of the water infrastructure. The technology for the production of safe drinking is increasingly dependent on these more diverse sources and a key enabling technology is membrane filtration. While membrane system are effective, the operating costs of such systems are hampered by fouling which increases the energy requirement for process operation. The unique idea of this Proof of Concept is to develop an electrospun nanostructured membrane which can be integrated into water filtration technologies. The unique method of fabrication will produce an inherently antibacterial and antibiofouling surface in a one-step process, cutting the number of manufacturing steps. This concept, when deployed commercially is expected to dramatically reduce the operating costs of membrane processes for water treatment. The commercialisation route of the product will be through the patent protection and the licensing of the technology with a view to rapid commercialisation.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["768731"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["LUNDS UNIVERSITET"], "EU_Contribution": ["EUR 173 857,20"], "Project_Title": ["Next generation nanowire solar cells"], "Total_Cost": ["EUR 173 857,20"], "Country": ["Sweden"], "Project_ACR": ["NEXTNANOCELLS"], "Technology_Description": "Nanowire solar cells are an innovative and promising way to further reduce the cost of photovoltaic electricity for terrestrial applications. Accordingly, the ultimately goal of this project is to develop a multi-junction solar cell composed of an array of III-V nanowire subcells, electrically connected to a state-of-the-art Si solar cell. In order to do so, two different epitaxial techniques will be used to accomplish the epitaxial growth of the nanowires: standard MOVPE growth and the ground-breaking technology of Aerotaxy. Then, the nanowires will be embedded in a polymer and transferred to a Si substrate. ", "To": ["2017-07-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-08-01"], "Project_ID": ["656208"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["WEIZMANN INSTITUTE OF SCIENCE", "WEIZMANN INSTITUTE OF SCIENCE"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Producing hydrogen by water splitting"], "Total_Cost": ["EUR 150 000"], "Country": ["Israel", "Israel"], "Project_ACR": ["watersplit"], "Technology_Description": "This proposal describes a plan to prove the role of electrons\u2019 spin in the photocatalyzed oxidation of water; reaction of two water molecules to form two hydrogen molecules and a single oxygen molecule in its triplet ground state. We found that the catalyst performance is affected by its chiral symmetry, or lack thereof. It is well known that the electrochemical and photoelectrochemical splitting of water requires a high overpotential and that it can be changed by the choice of catalyst; however, the origin of the overpotential was not fully understood. In addition, the artificial water splitting reaction is commonly hampered by the production of hydrogen peroxide, which reduces the hydrogen yield and acts as a strong oxidation agent that can damage the electrochemical cell. The proposed studies will build on our new results which suggest that the chirality of the photoanode material can reduce the overpotential for water splitting and enhance the reaction rate. We found that spin-polarized current causes a spin correlation between the two OH intermediates in the reaction. This spin correlation could both suppress production of hydrogen peroxide and enhance the formation rate of oxygen molecules in the triplet state, improving water splitting efficiency. ", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["764203"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 212 194,80"], "Project_Title": ["A Realizability Approach to Complexity Theory"], "Total_Cost": ["EUR 212 194,80"], "Country": ["Denmark"], "Project_ACR": ["ReACT"], "Technology_Description": "\"Complexity theory concerns fundamental questions on the mathematics of computer science about the amount of resources needed to run programs or solve problems. The ReACT project will build on recent work in realizability models for linear logic to provide new characterizations of existing complexity classes. The end goal is to enable researchers to attack long-standing open problems in complexity theory by using mathematical techniques, tools and invariants from operators algebras and dynamical systems.", "To": ["2017-10-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-11-01"], "Project_ID": ["659920"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE UNIVERSITY OF WARWICK"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Sustainable steel braced frame for multi-hazard mitigation"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SustBracedMHaz"], "Technology_Description": "Modern societies need building infrastructure that is designed and maintained according to high sustainability and resilience standards. Sustainability in construction can be realized with demountable (easy to deconstruct) structures that enable change of the building geometry (adaptability) and reuse of materials and structural members at the end of the building life. Resilience can be realized with structures that can be easily repaired, if damaged, so that building service can be restored within an acceptable short, if not immediate, time after extreme loading conditions. Moreover, the need to design structures against multiple natural (e.g. earthquakes) and man-made (e.g. bomb blast) hazards has been recognized. The goal of the project is to address the aforementioned urgent societal needs by developing a novel steel concentric braced frame (CBF) that can, for the first time, simultaneously achieve the following overall objectives: (a) Sustainability in construction, (b) Enhanced progressive collapse resistance and reparability against a sudden loss of column due to bomb blast; and (c) Easy inspection and repair of damage to allow rapid return to building use and occupation after strong earthquakes.", "To": ["2017-08-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-08-31"], "Project_ID": ["654424"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["SPECTROSWISS SARL", "SPECTROSWISS SARL"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Precision mass spectrometry to leverage applications in life and environmental sciences"], "Total_Cost": ["EUR 150 000"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["Precision4Life"], "Technology_Description": "The unbeatable performance leaders in molecular analysis of biological and environmental samples are the Fourier transform mass spectrometers (FTMS): Orbitrap FTMS and ion cyclotron resonance (FT-ICR MS). However, even FTMS approaches suffer from performance limitations when facing the molecular complexity of samples in modern applications. The primary reasons for these limitations are the space charge effects \u2013 strong Coulombic interactions of many ions oscillating in the trapping devices. Applications suffering from space charge affects include those with (i) significant fluctuation of incoming ion currents; (ii) close spacing of molecular mass/charge ratios to be resolved; and (iii) high spectral dynamic range of ion intensities. To address these performance challenges and as a result of the completed ERC Starting Grant, we propose to increase precision of mass measurements in FT-ICR MS by using the direct cyclotron frequency measurements instead of the space charge-sensitive reduced cyclotron frequency measurements employed currently. We have confirmed the principal feasibility of FT-ICR MS at the cyclotron frequency on both types of commercial FT-ICR MS instruments on the lab level. The aim of our PoC grant application is to realize the benefits of FT-ICR MS at the cyclotron frequency by developing and seamlessly integrating the laboratory-level innovation into commercial instruments at an industry-grade level to leverage life and environmental sciences applications. The action plan includes: (i) enabling integration of prototype ICR mass analyzers into commercial FT-ICR MS instruments via feasibility studies and pilot projects; (ii) analyzing competitive advantages of the project\u2019s outcomes over existing products and workflows, with a focus on frequency (mass) precision increase; (iii) clarifying IPR position, strategy; and (iv) performing market analysis.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-07-01"], "Project_ID": ["768565"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["EUROPEAN FUTURE INNOVATION SYSTEM CENTRE", "JNP STRATIGIKI KAI EPICHIRISIAKI SYMVOULEFTIKI IKE", "ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON", "GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER", "GEANT LIMITED", "PARTNERSHIP FOR ADVANCED COMPUTINGIN EUROPE AISBL", "STICHTING EGI", "THE UNIVERSITY OF EDINBURGH", "CONSIGLIO NAZIONALE DELLE RICERCHE"], "EU_Contribution": ["EUR 1 499 037,50"], "Project_Title": ["European E-Infrastructure Services Gateway"], "Total_Cost": ["EUR 1 499 037,50"], "Country": ["Belgium", "Greece", "Greece", "Germany", "United Kingdom", "Belgium", "Netherlands", "United Kingdom", "Italy"], "Project_ACR": ["eInfraCentral"], "Technology_Description": "EInfraCentral's mission is to ensure that by 2020 a broader/ more varied set of users (including industry) benefits from European infrastructures. A common approach to defining and monitoring e-infrastructures services will increase their uptake. It will also enhance understanding of where improvement can be made in delivering services. The challenge is to shift towards an e-Infrastructure ''market place'' to initiate new service offerings and to engage with a broader set of users and needs. This will be achieved through an exchange of know-how between e-infrastructures consultations with a broad range of existing or potential users. EInfraCentral will pursue 3 specific objectives: 1. Structure an open and guided discussion between e-infrastructures to consensually define a common service catalogue 2. Develop a one-stop shop portal for users to browse the service catalogue and enhance the monitoring of key performance indicators that focus on availability and quality of services and user satisfaction 3. Draw policy lessons for a future European e-infrastructure market place as an extension of the common service catalogue and portal (incorporating a larger number of e-infrastructures). Key highlights of the proposal are: 1.A multidisciplinary team combining technical knowledge & insights from the e-infrastructure community with independent expertise in community building consultation, policy and data mapping and monitoring 2. A co-design process that will involve funders, the e-research infrastructure community and a representative user group (incl. SMEs) 3. On-going user interaction will guide the design and development of the eInfraCentral portal (as the main entry point to European e-infrastructures services) in two phases: a prototype with a first set of services and a full release with a KPI dashboard 4. Reinforce collaboration between e-infrastructures and optimise access to and increase uptake of e-infrastructures services by end users.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["INFRASUPP-03-2016 - Support to policies and international cooperation for e-infrastructures"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Belgium"], "Activity": ["Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other", "Other", "Other", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2017-01-01"], "Project_ID": ["731049"], "Call_for_Proposal": ["H2020-INFRASUPP-2016-1"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 2 283 955"], "Project_Title": ["Stratified turbulence and mixing processes"], "Total_Cost": ["EUR 2 283 955"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["STAMP"], "Technology_Description": "We propose to study turbulence and mixing in stably stratified fluid. Mixing is central to a wide range of questions from the heat uptake in the global ocean, the transport and dilution of pollutants in the atmosphere, the efficient cooling of buildings, to the homogenising of products in the food industry. However, the mechanisms that are responsible and their physical and dynamical aspects are largely unknown, and it is not possible to predict mixing rates from a knowledge of the overall flow and density fields.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["742480"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["KAROLINSKA INSTITUTET", "KAROLINSKA INSTITUTET"], "EU_Contribution": ["EUR 2 413 449"], "Project_Title": ["Mimicking liver disease and regeneration in vitro for drug development and liver transplantation"], "Total_Cost": ["EUR 2 413 449"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["HEPASPHER"], "Technology_Description": "The liver is a vital organ for synthesis and detoxification. The most significant liver diseases are hepatitis, non alcoholic fatty liver disease (NAFLD), non-alcoholic fatty liver steatohepatitis (NASH), carcinoma and cirrhosis. An additional and important cause of liver injury is adverse drug reactions (ADRs). In particular NAFLD is the most common liver disease affecting between 20% and 44% of European adults and 43-70% of patients with type 2 diabetes, and is one prime cause for chronic and end-stage liver disease, such as cirrhosis and primary hepatocellular carcinoma. ", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["742020"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["LUNDS UNIVERSITET", "LUNDS UNIVERSITET"], "EU_Contribution": ["EUR 2 500 000"], "Project_Title": ["Immunity in Ecology and Evolution: 'Hidden' costs of disease, immune function and their consequences for Darwinian fitness"], "Total_Cost": ["EUR 2 500 000"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["EcoImmuneCosts"], "Technology_Description": "Eco-immunology targets one of the great challenges in biology and medicine - how the immune system has evolved to optimize protection and minimize immunopathology (incl. autoimmune) costs. A primary target of my proposal is to study low-virulent pathogens causing mild infections, which for long have been considered harmless. Recent research suggests that this notion is false and that seemingly harmless pathogens entail delayed (\u2018hidden\u2019) fitness costs. However, the mechanisms mediating these costs are still unknown. I will experimentally test if accelerated telomere degradation is a causative mechanism through which small immune costs can accumulate and be translated into senescence and reduced Darwinian fitness. Another key target is immune costs, which may be \u2018hidden\u2019 because of sexually antagonistic effects, and I will study how this may affect immune gene variation, immune costs and Darwinian fitness. These aspects are central for advancing our understanding of the evolution of disease resistance and immune function, incl. immune over-reactions (autoimmunity).", "To": ["2022-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["742646"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERZA V MARIBORU", "UNIVERZA NA PRIMORSKEM UNIVERSITA DEL LITORALE", "UNIVERZA V NOVI GORICI", "NACIONALNI INSTITUT ZA BIOLOGIJO", "GIMNAZIJA FRANCA MIKLOSICA LJUTOMER"], "EU_Contribution": ["EUR 158 994,50"], "Project_Title": ["Science for Life"], "Total_Cost": ["EUR 158 994,50"], "Country": ["Slovenia", "Slovenia", "Slovenia", "Slovenia", "Slovenia"], "Project_ACR": ["SciFe"], "Technology_Description": "Main objectives of the SciFe proposal is to bring researchers to the general public, to inspire youngster to embark on scientific careers, to increase awareness of importance of research and innovation activities, with a view to supporting the public recognition of researchers creating an understanding of the impact of researchers' work on citizen's daily life. For that purpose the awareness campaign (AC) to convey messages under the slogan \u201cScience for Life\u201d will be used in 2016 and 2017. On Fridays 30.9.\u201916 and 29.9.\u201917 SciFe events will be organized with renewed programs in festive and fun atmosphere in Ljutomer, Maribor, Bre\u017eice, Ljubljana, Koper, Izola and Nova Gorica. All SciFe events\u2019 activities aim at offering the public at large an opportunity to cooperate in fascinating experiments, demonstrations, observations etc., to socialize and have fun with researchers in a relaxed atmosphere. The program is appropriate for public in general, regardless their scientific program and especially designed for youngest. SciFe programs\u2019 red line is contribution of science to life in various aspects. The \u00bbEuropean corner\u00ab will be prepared in the heart of every RN location: the visitors will be offered information on EC\u2019s various actions and programs, EU material, \u201cthe Charter and the Code\u201d, information how young people can become researchers and Framework Program witness\u2019s experiences. Intensive awareness campaign is designed according to its main target. The rich communication mix includes active engagement of the young people through the public call targeting primary and secondary schools. Last but not least, the impact assessment will focus to measure the success and the impact of SciFe activities. All that will be achieved through consortium management of all WPs and harmonised communication mix with general public which takes into account existing recognition of the RN event in certain region and its number of inhabitants.", "To": ["2017-11-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-NIGHT-2016 - European Researchers' Night"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Slovenia"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2016-04-01"], "Project_ID": ["722990"], "Call_for_Proposal": ["H2020-MSCA-NIGHT-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 2 043 630"], "Project_Title": ["Active and Driven Systems: Nonequilibrium Statistical Physics"], "Total_Cost": ["EUR 2 043 630"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["ADSNeSP"], "Technology_Description": "Active Matter systems, such as self-propelled colloids, violate time-reversal symmetry by producing entropy locally, typically converting fuel into mechanical motion at the particle scale. Other driven systems instead produce entropy because of global forcing by external fields, or boundary conditions that impose macroscopic fluxes (such as the momentum flux across a fluid sheared between moving parallel walls). ", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["740269"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET", "KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 1 997 592,92"], "Project_Title": ["Repair capacity and genome diversity in mammals"], "Total_Cost": ["EUR 1 997 592,92"], "Country": ["Denmark", "Denmark"], "Project_ACR": ["ReCAP"], "Technology_Description": "Genome evolution is driven by the generation of diversity. In mammals, genome diversification occurs in germline during the specialised division (meiosis) in gametes, when chromosomes recombine and assort into new haploid sets as they are passed from parent to offspring. Recently, the traditional view that genome diversification occurs exclusively in the germline has been challenged by findings that mutations in early embryos may cause predisposition to childhood cancers. We are uniquely placed to explore genome diversification in the germline and early embryos due to our breakthroughs in developing single-cell genomics and reproductive technologies. ", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["724718"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITY OF NEWCASTLE UPON TYNE", "UNIVERSITY OF NEWCASTLE UPON TYNE"], "EU_Contribution": ["EUR 1 995 677"], "Project_Title": ["Who is that? Neural networks and mechanisms for identifying individuals"], "Total_Cost": ["EUR 1 995 677"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["MECHIDENT"], "Technology_Description": "Our social interactions and survival critically depend on identifying specific individuals to interact with or avoid (\u201cwho is that?\u201d). Identifying individuals can be achieved by different sensory inputs, and by many accounts any sensory input elicits a representation of an individual that somehow becomes transmodal or independent of any sensory system. However, how the brain achieves transmodal integration facilitating individual recognition remains a mystery: Investigations in humans allowing direct access to site-specific neuronal processes are generally rare and have not focused on understanding neuronal multisensory integration for person recognition. Also, animal models to study the neuronal mechanisms of related processes have only recently become known. I propose to use direct recordings of neuronal activity in both humans and monkeys during face- and voice-identification tasks, combined with site-specific manipulation of the sensory input streams into the lateral anterior temporal lobe (ATL). The ATL brings together identity-specific content from the senses but the neuronal mechanisms for this convergence are entirely unknown. My core hypothesis is that auditory voice- or visual face-identity input into key ATL convergence sites elicits a sensory-modality invariant representation, which once elicited is robust to degradation or inactivation of neuronal input from the other sense. The central aim is to test this in human patients being monitored for surgery and to directly compare and link the results with those in monkeys where the neuronal circuit and mechanisms can be revealed using optogenetic control of neuronal responses. Analyses will assess neuronal dynamics and sensory integration frameworks. This proposal is poised to unravel how the brain combines multisensory input critical for identifying individuals and cognitive operations to act upon. The basic science insights gained may inform efforts to stratify patients with different types of ATL damage.", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["724198"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITEIT GENT", "UNIVERSITEIT GENT"], "EU_Contribution": ["EUR 1 427 625"], "Project_Title": ["Photonics in Flatland: Band Structure Engineering of 2D Excitons in Fluorescent Colloidal Nanomaterials"], "Total_Cost": ["EUR 1 427 625"], "Country": ["Belgium", "Belgium"], "Project_ACR": ["PHOCONA"], "Technology_Description": "In PHOCONA we aim to develop a new class of highly fluorescent 2D and quasi-2D colloidal nanomaterials for solution-processed coherent light sources and ultrafast single-photon emitters. The 2D excitons are created in suspended semiconductor nanoplates with a thickness below 5 nm, and transition-metal dichalcogenide monolayers. Prepared by colloidal chemistry and liquid-phase exfoliation, respectively, they take advantage of both quantum confinement through their nanoscale dimensions, as well as dielectric confinement via the dielectric mismatch between nanomaterials and surrounding matrix. Via smart nanocrystal design, more specifically by exploiting novel synthesis methods that include asymmetric in-plane confinement potentials, anisotropic crystal structures, and lattice strain-induced band structure modifications in core/shell heterostructures, the nanomaterials will be shaped toward efficient multiexciton and stimulated emission, as well as stable, blinking-free single-photon emission. The intrinsic 2D exciton properties will be further modified toward ultrafast exciton recombination by coupling the nanomaterials to small mode-volume plasmonic nanocavities, hereby placing them in a local photon density-of-states that will lead to a strong Purcell enhancement. The realization of cost-effective, energy-efficient and highly flexible light emitters, which can be synthesized and processed via methods that are scalable to large areas and volumes, forms an important milestone in the ongoing development of optical and quantum communications technology, as well as new lighting and display applications.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["714876"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE", "INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE"], "EU_Contribution": ["EUR 1 498 751,25"], "Project_Title": ["Boosting Brain-Computer Communication with high Quality User Training"], "Total_Cost": ["EUR 1 498 751,25"], "Country": ["France", "France"], "Project_ACR": ["BrainConquest"], "Technology_Description": "Brain-Computer Interfaces (BCIs) are communication systems that enable users to send commands to computers through brain signals only, by measuring and processing these signals. Making computer control possible without any physical activity, BCIs have promised to revolutionize many application areas, notably assistive technologies, e.g., for wheelchair control, and human-machine interaction. Despite this promising potential, BCIs are still barely used outside laboratories, due to their current poor reliability. For instance, BCIs only using two imagined hand movements as mental commands decode, on average, less than 80% of these commands correctly, while 10 to 30% of users cannot control a BCI at all.", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-07-01"], "Project_ID": ["714567"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF EV", "HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF EV"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["All-electrical analytic platform for digital fluidics"], "Total_Cost": ["EUR 150 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["ANALYTICS"], "Technology_Description": "Prospective biosensing technologies will need to tackle the grand challenges arising from the global demographic changes. Among the most crucial tasks is the monitoring of food and environmental quality as well as the medical diagnosis. Digital fluidics offers vast advantages in performing these tasks relying on tiny containers with reacting biochemical species and allowing massively parallelized assays and high throughput screening using optical detection approaches. ", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2017-PoC - ERC-Proof of Concept"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["768584"], "Call_for_Proposal": ["ERC-2017-PoC"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON", "UNIVERSITY COLLEGE LONDON", "UNIVERSITY COLLEGE LONDON HOSPITALSNHS FOUNDATION TRUST"], "EU_Contribution": ["EUR 2 497 841"], "Project_Title": ["Understanding cancer development in BRCA 1/2 mutation carriers for improved Early detection and Risk Control"], "Total_Cost": ["EUR 2 497 841"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom"], "Project_ACR": ["BRCA-ERC"], "Technology_Description": "Recent evidence demonstrates that cancer is overtaking cardiovascular disease as the number one cause of mortality in Europe. This is largely due to the lack of preventative measures for common (e.g. breast) or highly fatal (e.g. ovarian) human cancers. Most cancers are multifactorial in origin. The core hypothesis of this research programme is that the extremely high risk of BRCA1/2 germline mutation carriers to develop breast and ovarian cancer is a net consequence of cell-autonomous (direct effect of BRCA mutation in cells at risk) and cell non-autonomous (produced in distant organs and affecting organs at risk) factors which both trigger epigenetic, cancer-initiating effects. ", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["742432"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["TTY-SAATIO", "TTY-SAATIO"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Pre-Commercialisation of Sound Recognition for Surveillance Applications"], "Total_Cost": ["EUR 150 000"], "Country": ["Finland", "Finland"], "Project_ACR": ["SMARTSOUND"], "Technology_Description": "Audio communication is a major tool for businesses to maintain their competitiveness in the global market. This market is expected to treble by 2020 to $2.145 billion and creates a great demand for novel ideas, such as acoustic pattern recognition technologies. Similarly, the explosion in big data is calling for new data classification methods for improved data indexation and real-time monitoring of the data streams. ", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["737472"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["ISTITUTO NAZIONALE DI FISICA NUCLEARE", "HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF EV", "Prisma Electronics ABEE", "POLITECNICO DI MILANO", "CLEVER OPERATION", "UNIVERSITA DEGLI STUDI DI GENOVA", "UNIVERSITA DI PISA", "STOCKHOLMS UNIVERSITET", "KUNGLIGA TEKNISKA HOEGSKOLAN", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSITA DEGLI STUDI DI PERUGIA", "UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA", "IMPEX HIGHTECH GMBH", "EUROPEAN GRAVITATIONAL OBSERVATORY", "UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II."], "EU_Contribution": ["EUR 1 566 000"], "Project_Title": ["NEw WindowS on the universe and technological advancements from trilateral EU-US-Japan collaboration"], "Total_Cost": ["EUR 1 566 000"], "Country": ["Italy", "Germany", "Greece", "Italy", "France", "Italy", "Italy", "Sweden", "Sweden", "France", "Italy", "Italy", "Germany", "Italy", "Italy"], "Project_ACR": ["NEWS"], "Technology_Description": "NEWS promotes the collaboration between European, US and Japanese research institutions in some key areas of fundamental physics. LIGO and Virgo collaborations have built the largest gravitational wave observatories and exploit the propagation of light and spacetime to detect gravitational waves and probe their sources. The first observation of a signal from a merging black hole system has inaugurated the era of gravitational wave astronomy. The Large Area Telescope collaboration operates a gamma-ray telescope onboard the Fermi Gamma Ray Space Telescope mission and has revolutionized our view of the gamma-ray Universe, by increasing the number of known sources, unveiling new classes of gamma-ray emitters, and probing particle acceleration and electromagnetic emission in space with unprecedented detail. Fermi is the reference all-sky gamma-ray monitor for the follow-up searches for electromagnetic counterparts of gravitational wave sources. The multimessenger astronomical observations will soon be enriched by X-ray polarization detectors. New-generation space telescopes will measure the polarization of X-rays from the cosmic sources and probe the laws of physics under extreme conditions of gravitational and electromagnetic fields. A complementary approach to probe the Universe is provided by particle accelerators built in laboratories. FNAL will provide the cleanest probes for physics beyond the Standard Model of particle physics. The Muon (g-2) experiment will measure the muon anomalous magnetic moment with unprecedented precision. Mu2e will search for the neutrinoless coherent muon conversion to an electron in the Coulomb field of a nucleus, which would be the unambiguous evidence of new, unknown, physics. These endeavors require innovative detectors and cutting-edge technologies that NEWS will develop to open new \u201cwindows\u201d in fundamental physics.", "To": ["2021-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["734303"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI GENOVA", "UNIVERSITA DEGLI STUDI DI GENOVA"], "EU_Contribution": ["EUR 2 396 643,75"], "Project_Title": ["Detection, simulation, modelling and loading of thunderstorm outflows to design wind-safer and cost-efficient structures"], "Total_Cost": ["EUR 2 396 643,75"], "Country": ["Italy", "Italy"], "Project_ACR": ["THUNDERR"], "Technology_Description": "Wind actions are crucial for the safety and cost of structures.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["741273"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON", "UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 149 062"], "Project_Title": ["Antibiotic intracellular delivery via virus-like carriers"], "Total_Cost": ["EUR 149 062"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["AIDViC"], "Technology_Description": "Taking inspiration from natural carriers, such as viruses, a new technology has been developed in our laboratories part of an ongoing ERC starting grant project, Molecular Engineering of Virus-like Carriers (MEViC). We created synthetic viruses using polymers and thus safer materials. They are able of delivering high payload of specific drugs into cells with no detrimental effect. While testing for anticancer therapies, we identified a synthetic virus capable of targeting almost exclusively macrophages. We performed preliminary work showing that this can be successfully applied to deliver antibiotics to rid of intracellular pathogens. This has now open a completely new possibility whereas we can expand our technology for the treatment of several infections as well as to contribute to the ongoing efforts in tackling antibiotic resistance.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["754704"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["RIJKSUNIVERSITEIT GRONINGEN", "RIJKSUNIVERSITEIT GRONINGEN", "VRIJE UNIVERSITEIT BRUSSEL"], "EU_Contribution": ["EUR 2 499 418,75"], "Project_Title": ["Family ties that bind: A new view of internal migration, immobility and labour-market outcomes"], "Total_Cost": ["EUR 2 499 418,75"], "Country": ["Netherlands", "Netherlands", "Belgium"], "Project_ACR": ["FamilyTies"], "Technology_Description": "Internal migration (long-distance moves within national borders) is generally assumed to be beneficial to individuals and households. This FamilyTies project has been designed to make a decisive contribution to a much more comprehensive explanation of internal migration and its labour-market outcomes than current, mainly economic, explanations have achieved thus far. It introduces a novel perspective on internal migration and immobility, which focuses on the role of family outside the household in deciding on whether and where to relocate, and which takes into account contemporary family complexity: the family ties perspective. The aim is to identify the role of family ties in internal migration, immobility and labour-market outcomes. The objectives are:", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["740113"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["MEDICAL RESEARCH INFRASTRUCTURE DEVELOPMENT AND HEALTH SERVICES FUND BY THE SHEBA MEDICAL CENTER", "MEDICAL RESEARCH INFRASTRUCTURE DEVELOPMENT AND HEALTH SERVICES FUND BY THE SHEBA MEDICAL CENTER"], "EU_Contribution": ["EUR 2 457 500"], "Project_Title": ["Transcriptomic m1A - a new key player in the epitranscriptome arena"], "Total_Cost": ["EUR 2 457 500"], "Country": ["Israel", "Israel"], "Project_ACR": ["m1ARNA"], "Technology_Description": "Reversible epigenetic modifications regulate gene expression to define cell fate and response to environmental stimuli. Gene expression tuning by DNA and chromatin modifications is well studied, yet the effect of RNA modifications on gene expression is only starting to be revealed. More than a hundred chemical modifications decorate RNAs, mainly non-coding ones, expanding their nucleotide vocabulary and mediating their diverse functions. Several modifications were globally mapped in mRNA. Only two, N6-methyladenosine (m6A) and N1-methyladenosine (m1A) exhibit a distinct topology alluding to a functional role. We pioneered the identification of m6A that is located preferentially in distinct transcript landmarks, mostly around stop codons and mediates transcript localization, splicing, decay and translation. We now identified m1A which decorates thousands of genes mainly in the start codon vicinity, upstream to the first splice site. Our preliminary results indicate that m1A dynamically responds to environmental stimuli and plays a central role in translation regulation. The regulation and functions of m1A are still terra incognita. Our objectives are to identify m1A writers and erasers, elucidate m1A readers and the mechanisms whereby m1A dictates downstream outcomes, particularly translation regulation. We will study m1A functions in response to physiologic stimuli and stress conditions in cells and animal models by manipulation of the m1A deposition machinery. As epigenetic marks operate in a context-dependent concerted way we will map m1A marks concomitantly with m6A to decipher their interplay in regulating gene expression via a putative \u201cepigenetic RNA code\u201d. The data obtained from parallel mapping of m1A and m6A at a single nucleotide and a single transcript resolution, will expose the interplay between these two mRNA modifications in the context of multilayer epigenetics. The study of m1A circuits may identify targets amenable to therapeutic manipulations.", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Israel"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-07-01"], "Project_ID": ["743168"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["ECOLE POLYTECHNIQUE", "ECOLE POLYTECHNIQUE"], "EU_Contribution": ["EUR 2 472 752"], "Project_Title": ["Charting a New Horizon of Big and Fast Data Analysis through Integrated Algorithm Design"], "Total_Cost": ["EUR 2 472 752"], "Country": ["France", "France"], "Project_ACR": ["BigFastData"], "Technology_Description": "This proposal addresses a pressing need from emerging big data applications such as genomics and data center monitoring: besides the scale of processing, big data systems must also enable perpetual, low-latency processing for a broad set of analytical tasks, referred to as big and fast data analysis. Today\u2019s technology falls severely short for such needs due to the lack of support of complex analytics with scale, low latency, and strong guarantees of user performance requirements. To bridge the gap, this proposal tackles a grand challenge: \u201cHow do we design an algorithmic foundation that enables the development of all necessary pillars of big and fast data analysis?\u201d This proposal considers three pillars: ", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["725561"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["CENTRO DE ESTUDOS SOCIAIS", "CENTRO DE ESTUDOS SOCIAIS"], "EU_Contribution": ["EUR 1 915 381"], "Project_Title": ["The politics of anti-racism in Europe and Latin America: knowledge production, decision-making and collective struggles"], "Total_Cost": ["EUR 1 915 381"], "Country": ["Portugal", "Portugal"], "Project_ACR": ["POLITICS"], "Technology_Description": "The main objective of POLITICS is to innovate knowledge on anti-racism that brings about a greater understanding of how historically rooted injustices are being challenged by institutions and grassroots movements. Considering the centrality and mutual influence of Europe and Latin America in the global processes of racial formation, POLITICS will develop an inter-disciplinary and comprehensive approach towards two core goals: (a) the analysis of processes of knowledge production about \u2018race\u2019 and (anti-)racism in the spheres of (inter)national governmental politics, State universities and grassroots movements; (b) the examination of diverse paths of denunciation and collective mobilisation against everyday racism concerning police practice and representations in the mass media. ", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Portugal"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["725402"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["FUNDACION PRIVADA INSTITUTO DE SALUD GLOBAL BARCELONA"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Acclimatization scenarios and early warning system of temperature-related mortality in Europe"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["ACCLIM"], "Technology_Description": "The research proposed in this project is focused on the study of one of the most challenging and potentially-dangerous impacts of climate in European societies: the mortality associated with environmental temperatures in the current context of global warming. The research objectives of the proposal are (i) the description of the dependency between counts of deaths and climate variables contributing to increased body stress, (ii) the inference of future projections of mortality under scenarios of increased greenhouse gas concentrations, (iii) the study of the effect of adaptation measures on these projections, and (iv) the development of an early warning system of mortality risk as a climate service for European societies. During the implementation of all these objectives, the main results and conclusions of the research will be communicated to the general public and disseminated in specialized circles within and outside the research field. The research and methodology here proposed are clearly innovative, given that the project will integrate climate information and tools with unprecedented high-quality mortality and sociodemographic data in a multidisciplinary approach that will take into account the degree of adaptability of human societies and individuals to scenarios of increased greenhouse gas concentrations in the atmosphere. In this sense, the design of the proposal clearly fits into the main guidelines and objectives defined by the European Commission in the work programme of the initiative Horizon 2020, which contributes to the generation of climate services that provide useful guidance to health care systems, governments and policy makers throughout Europe.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-10-01"], "Project_ID": ["737480"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH", "HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH"], "EU_Contribution": ["EUR 1 498 175"], "Project_Title": ["Mucosal Tolerance and Allergic Predisposition: Does it all start in the gut?"], "Total_Cost": ["EUR 1 498 175"], "Country": ["Germany", "Germany"], "Project_ACR": ["ALLERGUT"], "Technology_Description": "Currently, more than 30% of all Europeans suffer from one or more allergic disorder but treatment is still mostly symptomatic due to a lack of understanding the underlying causality. Allergies are caused by type 2 immune responses triggered by recognition of harmless antigens. Both genetic and environmental factors have been proposed to favour allergic predisposition and both factors have a huge impact on the symbiotic microbiota and the intestinal immune system. Recently we and others showed that the transcription factor ROR(\u03b3t) seems to play a key role in mucosal tolerance in the gut and also regulates intestinal type 2 immune responses. ", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-07-01"], "Project_ID": ["716718"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["THE UNIVERSITY OF EXETER", "THE UNIVERSITY OF EXETER", "UNIVERSITY OF OTAGO"], "EU_Contribution": ["EUR 1 498 337"], "Project_Title": ["The evolutionary ecology of bacterial immune mechanisms"], "Total_Cost": ["EUR 1 498 337"], "Country": ["United Kingdom", "United Kingdom", "New Zealand"], "Project_ACR": ["EVOIMMECH"], "Technology_Description": "Bacteria have a range of immune mechanisms, but it is unclear why this diverse armamentarium evolved. The most important immune mechanisms are (1) Surface Modification (SM) (2) Abortive infection (Abi) (3) Restriction Modification (R-M) (4) CRISPR-Cas and (5) prokaryotic Argonaute (pAgo), all of which can occur as stand-alone mechanisms or in combination. The individual mechanisms differ in key aspects, such as their fitness costs (constitutive versus inducible), specificity (indiscriminate versus specific), the recipient of the benefits (individual versus group), the speed of de novo resistance evolution (rapid versus slow), and heritability of immunity. Here I will take a combined in vitro and in vivo approach to tease apart the variables that drive the evolution of these diverse stand-alone and integrated bacterial immune strategies in nature, and examine their associated co-evolutionary dynamics. I focus on three ecological variables that are consistently important in host-symbiont co-evolution: (1) force of infection (2) spatial structure (3) presence of mutualists (plasmids). First, I will perform in vitro manipulations using Pseudomonas aeruginosa PA14 variants that carry either single or multiple immune mechanisms. Next, I will sequence metagenomes, transcriptomes and viromes of microbial communities from environments that differ in ecological variables that are important in vitro, to examine their importance in vivo. Key ecological mechanisms identified in the first two parts of the project will be used to guide mesocosm experiments to experimentally confirm that these mechanisms are the drivers of the observed patterns of resistance and co-evolution in nature. Finally, I will share my data with mathematical biologists to generate theoretical models to predict and manipulate the evolution of bacterial immune mechanisms, which will facilitate tailored species protection in agriculture and industry. \u2003\u2003", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["714478"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["ERASMUS UNIVERSITEIT ROTTERDAM"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["The Aftermath of a Drug Withdrawal: Modeling Spillover Effects Across Countries and Across Categories"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["WITHDRAWAL AFTERMATH"], "Technology_Description": "The pharmaceutical market is one of the most important industries in the global economy. Projections are that spending on medicines will grow to 1.2 trillion US$ in 2016. Marketing has an important impact in this pharmaceutical industry, but has a particularly negative image. The growing pharmaceutical market increases the pressure for the regulators to approve new medicines and for firms the pressure to market their drugs to stay ahead of the competition. These forces have contributed to the fact that over the past decade many drugs were approved too early, and the number of withdrawn drugs has doubled. A drug withdrawal is when a drug is taken off the market, because it is considered to be harmful typically due to unexpected adverse effects (including deaths). Since the pharmaceutical market directly concerns population health, drug withdrawals can have disastrous consequences. ", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["654862"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["FUNDACIO CENTRE DE RECERCA EN SALUT INTERNATIONAL DE BARCELONA", "FUNDACION PRIVADA INSTITUTO DE SALUD GLOBAL BARCELONA", "LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE", "PRINS LEOPOLD INSTITUUT VOOR TROPISCHE GENEESKUNDE", "CORIS BIOCONCEPT SPRL", "UNIVERZITA KARLOVA", "BMD SOFTWARE LDA", "THE UNIVERSITY OF WARWICK", "INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 3 820 537,80"], "Project_Title": ["Control of leishmaniasis, from bench to bedside and community"], "Total_Cost": ["EUR 3 820 537,80"], "Country": ["Spain", "Spain", "United Kingdom", "Belgium", "Belgium", "Czech Republic", "Portugal", "United Kingdom", "France", "Spain"], "Project_ACR": ["EUROLEISH-NET"], "Technology_Description": "Leishmaniasis control is the topic for EUROLEISH-NET, a Marie Sklodowska-Curie \u2013 Innovative Training Network. Leishmaniasis is a neglected infectious disease and a major public health and veterinary problem that afflicts both developing countries and Europe. The current technological and epidemiological advances underpin the necessity to develop training programmes aiming at developing new tools and strategies to control of leishmaniasis. An excellent group of academic and non-academic institutions in Europe and abroad will host 15 PhD students who will receive training in this programme. The expertise and training that will be offered ranges from parasitology to molecular science, genetics, epidemiology and strategic interventions. The 15 research projects designed encompass drug discovery, drug resistance, diagnostics and vaccine development, population genetics, vector control and integrated control programmes. The designated project supervisors have proven track records of success in research and in training. The incorporation of trainee mobility into the network, together with the commitment, strong affiliations and technology transfer between the participants provide a highly synergistic framework for success. The EUROLEISH-NET coordinators have proven experience in laboratory, field, administrative and financial management, supported by a meticulously planned series of meetings and diligent monitoring of the progression of each researcher. We anticipate an extremely productive training and research output from EUROLEISH-NET. We expect to train the next generation of leading research scientists in this field, endowed with skills that are broadly and internationally transposable.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations"], "From": ["2015-01-01"], "Project_ID": ["642609"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["KAROLINSKA INSTITUTET", "UNIVERSITE DE BORDEAUX", "UNIVERSITA DEGLI STUDI DI MILANO", "DEUTSCHES ZENTRUM FUR NEURODEGENERATIVE ERKRANKUNGEN EV", "Janssen Pharmaceutica NV", "AXON NEUROSCIENCE SE"], "EU_Contribution": ["EUR 3 846 736,44"], "Project_Title": ["Synaptic Dysfunction in Alzheimer Disease"], "Total_Cost": ["EUR 3 846 736,44"], "Country": ["Sweden", "France", "Italy", "Germany", "Belgium", "Slovakia"], "Project_ACR": ["SyDAD"], "Technology_Description": "Given an overwhelming increase of dementia costs and an aging population, there is an urgent need for finding novel therapies for Alzheimer Disease (AD). We are, however, facing a large number of failed clinical trials and a retraction of the nervous system R&D programmes from several big pharmaceutical companies. Increased collaboration between academia and the private sector is required to overcome this challenge.", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-11-01"], "Project_ID": ["676144"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER", "WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER"], "EU_Contribution": ["EUR 1 336 562,50"], "Project_Title": ["Wayfinding Through Orientation"], "Total_Cost": ["EUR 1 336 562,50"], "Country": ["Germany", "Germany"], "Project_ACR": ["WayTO"], "Technology_Description": "Wayfinding is a task that we manage every day while going to work or on vacation. Although wayfinding research has gone through tremendous development, it suffers from fundamental shortcomings: State-of-the art wayfinding research still adheres to the principles of turn-by-turn navigation.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["637645"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["EUROPEAN SPACE AGENCY", "ADVANCED COMPUTER SYSTEMS A.C.S. SPA", "EXPERT SYSTEM IBERIA SL", "TERRADUE SRL", "METEOROLOGICAL AND ENVIRONMENTAL EARTH OBSERVATION SRL", "NATURAL ENVIRONMENT RESEARCH COUNCIL", "DEUTSCHES ZENTRUM FUER LUFT - UND RAUMFAHRT EV", "ALMA SISTEMI SAS DI DI IORIO ALESSIO & C", "EUROPEAN UNION SATELLITE CENTRE", "ISTITUTO NAZIONALE DI GEOFISICA E VULCANOLOGIA", "INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK", "CONSIGLIO NAZIONALE DELLE RICERCHE"], "EU_Contribution": ["EUR 6 561 627"], "Project_Title": ["European Virtual Environment for Research - Earth Science Themes"], "Total_Cost": ["EUR 6 561 627,50"], "Country": ["France", "Italy", "Spain", "Italy", "Italy", "United Kingdom", "Germany", "Italy", "Spain", "Italy", "Poland", "Italy"], "Project_ACR": ["EVER-EST"], "Technology_Description": "The EVER-EST project will enhance Research and Capacity Building in the Earth Science (ES) domain, by providing a generic Service Oriented-based Architecture Virtual Research Environment (VRE) tailored to the needs of the ES community. The full range of both generic and ES data management specific services provided by EVER-EST will facilitate the dynamic approach to collaborative working and research. Scientist will be able to discover, access, process, share and interoperate heterogeneous data, algorithms, results and experiences within and across their communities, including those in domains beyond Earth Science. Data providers will be able to monitor users experience and collect feedback through the VRE, improving their capacity to adapt to end-user needs offering solutions to unlock scientist potentials and creativity. EVER-EST e-infrastructure will be validated by four Virtual Research Communities (VRC) covering different multidisciplinary working ES domains: ranging from Sea Monitoring, to Natural Hazards (floods, weather, wildfires), Land Monitoring and Risk Management (volcanoes and seismic). Each of these VRC will use the VRE according to its own specific requirements for data, software, best practices and community engagement. The VRE will leverage on the results of several FP7 projects which have produced state-of-the-art technologies for scientific data management and curation. Such capabilities will be enriched during the EVER-EST project using the output of a second group of FP7 initiatives providing models, techniques and tools for the preservation of scientific methods and their implementation in computational forms such as scientific workflows. EVER-EST will implement solutions for data publication, citation and trust. EVER-EST will provide the means to climb up existing peaks and obstacles to information sharing in Earth Science allowing research teams to collaboratively collect, manipulate and share resources, allowing creation of new knowledge.", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["EINFRA-9-2015 - e-Infrastructures for virtual research environments (VRE)"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Research Organisations", "Research Organisations"], "From": ["2015-10-01"], "Project_ID": ["674907"], "Call_for_Proposal": ["H2020-EINFRA-2015-1"]}, -{"Partners": ["HOSPITAL UNIVERSITARIO DE FUENLABRADA", "HOSPITAL UNIVERSITARIO DE FUENLABRADA", "FUNDACION CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III"], "EU_Contribution": ["EUR 2 498 687,50"], "Project_Title": ["Integrating Genomics and Avatar Mouse Models to Personalize Pancreatic Cancer Treatment"], "Total_Cost": ["EUR 2 498 687,50"], "Country": ["Spain", "Spain", "Spain"], "Project_ACR": ["AVATAR"], "Technology_Description": "The prognosis of patients with metastatic pancreatic cancer (PDAC) is very poor. Recent studies have started to elucidate the genetic landscape of this disease to show that PDAC is a genetically complex, unstable, and heterogeneous cancer. However, in-depth analysis of individual patient genomes couple with personalize Avatar mouse models is providing highly effective therapeutic opportunities for the individual patient. Thus, metastatic PDAC appears a candidate disease to implement a genomics-base, personalized treatment approach. In this project, we will conduct an open label, multicenter, randomized phase III study in patients with standard of care resistant metastatic pancreatic cancer aiming to test the hypothesis that an integrated personalized treatment approach improves survival compare to a conventional treatment. Patients randomized to the personalize treatment arm will undergo a biopsy of a metastatic lesion to perform a targeted genome analysis using next generation sequencing. In addition, we will generate a personalize Avatar mouse model from the same patient. We will employ sophisticated bioinformatic analysis as well as mining of drug response-genetic databases to select, for each individual patient, candidate therapeutic targets that will be experimentally tested in the patient\u00b4s Avatar model to select the most effective regimen that will ultimately applied to the patient. In addition, based on the genomic data, we will design an individualized monitoring plan for each patient using BEAMing technology to monitor circulating levels of mutated genes. Furthermore, with a discovery goal, we will perform in depth genomic analysis of metastatic PDAC lesions in this cohort of clinically well-annotated patients with Avatar mouse models for therapeutic validation. Overall we expect this work will contribute to our understanding of PDAC and will favourably impact the treatment of this dismal cancer.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Spain"], "Activity": ["Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations"], "From": ["2015-10-01"], "Project_ID": ["670582"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["FORSCHUNGSVERBUND BERLIN EV", "FORSCHUNGSVERBUND BERLIN EV"], "EU_Contribution": ["EUR 1 996 500"], "Project_Title": ["In-cell NMR monitoring of alpha-Synuclein aggregation in neuronal cells"], "Total_Cost": ["EUR 1 996 500"], "Country": ["Germany", "Germany"], "Project_ACR": ["NeuroInCellNMR"], "Technology_Description": "Intracellular aggregation of the human amyloid protein alpha-synuclein is causally involved in Parkinson\u2019s disease, a debilitating neurodegenerative disorder. The goal of this project is to combine low-resolution, fluorescence-imaging methods with high-resolution in-cell NMR and EPR spectroscopy techniques to derive macroscopic and microscopic insights into alpha-synuclein aggregate structures directly in neuronal cells. ", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2015-11-01"], "Project_ID": ["647474"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["HELSINGIN YLIOPISTO", "HELSINGIN YLIOPISTO", "KOC UNIVERSITY"], "EU_Contribution": ["EUR 1 497 160"], "Project_Title": ["Deciphering and reversing the consequences of mitochondrial DNA damage"], "Total_Cost": ["EUR 1 497 160"], "Country": ["Finland", "Finland", "Turkey"], "Project_ACR": ["RevMito"], "Technology_Description": "Mitochondrial DNA (mtDNA) encodes several proteins playing key roles in bioenergetics. Pathological mutations of mtDNA can be inherited or may accumulate following treatment for viral infections or cancer. Furthermore, many organisms, including humans, accumulate significant mtDNA damage during their lifespan, and it is therefore possible that mtDNA mutations can promote the aging process.", "To": ["2020-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-04-01"], "Project_ID": ["637649"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["VILNIAUS UNIVERSITETAS"], "EU_Contribution": ["EUR 130 779,60"], "Project_Title": ["Eat me microglia: lipid scrambling as a signal for synaptic pruning"], "Total_Cost": ["EUR 130 779,60"], "Country": ["Lithuania"], "Project_ACR": ["LIPSYNING"], "Technology_Description": "The development of the nervous system is associated with the generation of excess neuronal synapses that is followed by their tightly controlled removal, a process known as synaptic pruning. In the primate cortex, for example, 70% of connections are selectively lost within the first six months of life. Why are so many synapses lost, what determines which synapses are eliminated, what are the molecular mechanisms involved, and what are the consequences of not getting it right? Recently, several studies have presented microglial phagocytosis as a mechanism for synapse elimination. Neural activity plays a role in synaptic pruning, but the neuronal \u201ceat-me\u201d signals that mediate phagocytic recognition and engulfment of synapses remain to be identified. We hypothesize that cell surface exposure of the lipid phosphatidylserine (PtdSer) is a key \u201ceat-me\u201d signal for synaptic pruning during development. Therefore we aim to define the role of PtdSer in synapse-microglia interaction and to assess the morphological, circuit maturation and behavioural effects of impaired PtdSer exposure in phospholipid scramblase-deficient brains. We propose to use novel custom-made tool to observe PtdSer exposure without interfering with PtdSer-dependent cellular interactions and two mouse models with disrupted PtdSer exposure to study how PtdSer contributes to circuit refinement. The identification of an \u201ceat-me\u201d signal will shed the light on what distinguishes synapses destined to be eliminated from those that survive and will be the first step in understanding why the majority of synapses are turned over during brain development before the final connectome emerges. As aberrant brain wiring during development is known to be defective in a wide range of neurodevelopmental disorders, understanding how circuits are formed and refined during developmental period will be critical to understand their aetiology and initiate the development of the therapy targeting molecular mechanisms of disease.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Lithuania"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["705452"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["VILNIAUS UNIVERSITETAS"], "EU_Contribution": ["EUR 130 779,60"], "Project_Title": ["Spin Transport in Interacting Spin-Orbit Coupled Systems"], "Total_Cost": ["EUR 130 779,60"], "Country": ["Lithuania"], "Project_ACR": ["SPINSOCS"], "Technology_Description": "The physics of charge and spin transport is the basis of current consumer devices. Recent discoveries in solid-state physics have highlighted the importance of the coupling of the electron\u2019s motion to its spin for transport phenomena. However, our understanding of transport with this so-called spin-orbit coupling has been largely limited to non-interacting systems, even though the first experimental systems with well-controlled spin-orbit coupling and interactions are already available.", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Lithuania"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["706839"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["CITY UNIVERSITY OF LONDON", "CHALMERS TEKNISKA HOEGSKOLA AB", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS", "UNIVERSITAET STUTTGART", "MITSUBISHI HITACHI POWER SYSTEMS EUROPE GMBH", "KARLSRUHER INSTITUT FUER TECHNOLOGIE", "UNIVERSITY COLLEGE LONDON", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "DELPHI AUTOMOTIVE SYSTEMS LUXEMBOURG SA"], "EU_Contribution": ["EUR 3 902 492,52"], "Project_Title": ["Holistic Approach of Spray Injection through a Generalized Multi-phase Framework"], "Total_Cost": ["EUR 3 902 492,52"], "Country": ["United Kingdom", "Sweden", "France", "Greece", "Germany", "Germany", "Germany", "United Kingdom", "United Kingdom", "Luxembourg"], "Project_ACR": ["HAoS"], "Technology_Description": "Development of fuel injection equipment (FIE) able to reduce pollutant emissions from liquid-fueled transportation and power generation systems is a top industrial priority in order to meet the forthcoming EU 2020 emission legislations. However, design of new FIE is currently constrained by the incomplete physical understanding of complex micro-scale processes, such as in-nozzle cavitation, primary and secondary atomization. Unfortunately, today\u2019s computing power does not allow for an all-scale analysis of these processes. The proposed program aims to develop a large eddy simulation (LES) CFD model that will account for the influence of unresolved sub-grid-scale (SGS) processes to engineering scales at affordable computing time scales. The bridging parameter between SGS and macro-scales flow processes is the surface area generation/destruction occurring during fuel atomisation; relevant SGS closure models will be developed through tailored experiments and DNS and will be implemented into the LES model predicting the macroscopic spray development as function of the in-nozzle flow and surrounding air conditions. Validation of the new simulation tool, currently missing from today\u2019s state-of-the-art models, will be performed against new benchmark experimental data to be obtained as part of the programme, in addition to those provided by the industrial partners. This will demonstrate the applicability of the model as an engineering design tool suitable for IC engines, gas turbines, fuel burners and even rocket engine fuel injectors. The proposed research and training programme will be undertaken by 15ESRs funded by the EU and one ESR funded independently from an Australian partner; ESRs will be recruited/seconded by universities, research institutes and multinational fuel injection and combustion systems manufacturers that will represent in the best possible way the international, interdisciplinary and intersectoral requirements of the Marie Curie Action guidelines.", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-11-01"], "Project_ID": ["675676"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["CHALMERS TEKNISKA HOEGSKOLA AB"], "EU_Contribution": ["EUR 185 857,20"], "Project_Title": ["Distributed storage based on sparse-graph codes"], "Total_Cost": ["EUR 185 857,20"], "Country": ["Sweden"], "Project_ACR": ["DISC"], "Technology_Description": "The recent years have witnessed the explosion of services and applications such as email, cloud computing, social and media networks, and video sharing. The grand challenge is to store, process and transfer this massive amount of data. According to recent estimates, the data to be stored grows at a rate of 45% per year, a factor of 40 by 2024. Data centers typically employ a collection of cheap devices/nodes, which are connected forming a so-called distributed storage (DS) system, where a central server keeps track of where each file is stored and performs all network operations. Every day, knowingly or unknowingly people connect to various private and public DS systems. It is nowadays accepted that current DS systems cannot face the unabated growing of digital data volume. Nextgeneration storage systems desperately need new technologies to improve their robustness to node failures, storage efficiency, complexity, and cost efficiency, in order to sustain the information revolution of modern societies. This project addresses the challenges above using modern coding theory and optimization theory. Our focus is on the application of sparse-graph erasure correcting codes to large DS networks. The proposed project falls into the category of fundamental research, but it is driven by practical concerns, and we expect our findings to give new and relevant insights for the design of practical coding schemes for next-generation DS systems.", "To": ["2017-04-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-05-01"], "Project_ID": ["658785"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE UNIVERSITY OF NOTTINGHAM"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Sputtering-deposition of metallic nanoparticles onto chiral ionic liquids andapplications in enantioselective hydrogenation"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SDchirnanocat"], "Technology_Description": "The production of fine chemicals, such as chiral molecules, is one of the main applications of the chemical industry. However, any new process developed should be environmentally sound. Metallic nanoparticles (MNPs) have attracted a large interest as catalytic materials due to their small size and high surface to bulk metal ratio, which leads to a greater catalytic activity. These catalysts are easily recyclable, although stabilizing agents are required to prevent agglomeration. In this context, ionic liquids (ILs), salts with melting point <100 \u00baC, can act both as stabilizers and as solvents. Moreover, MNPs may be immobilized in this medium, allowing the separation of the products and the subsequent recycling of the system. However, ILs are not \u201cinnocent\u201d media and can impose a high degree of directionality over the substrates. The employment of chiral ILs adds a new advantage: its potential use in asymmetric catalysis to induce the formation of chiral products. In this project we will merge the asymmetric properties of newly synthesized ILs with the catalytic activity of MNPs. Instead of classical chemical methods, MNPs in ILs will be obtained by sputtering-deposition (SD), an innovative physical technique which enables the fast synthesis of clean MNPs, avoiding the use of organic solvents and reducing agents. In contrast to other physical techniques, the SD of MNPs onto ILs allows the control of the size and shape of MNPs by the appropriate tuning of the sputtering conditions. These three concepts (MNP, chiral IL and SD) converge into the main aim of this project: The development of a novel chiral catalytic system based on MNPs prepared by SD onto chiral ILs for asymmetric hydrogenation reactions. SDchirnanocat will contribute to broaden the fellow competencies and will place him in an excellent position to start an independent career.", "To": ["2018-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-08-01"], "Project_ID": ["704710"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Nano-OptoMechanical Systems for Biological Sensors"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["NOMBIS"], "Technology_Description": "The emergence of antibiotic resistance is one of the major challenges in microbiology and medicine today. Early identification of the pathogens causing an infection and the rapid identification of antibiotic resistance is critical to provide the most effective drugs to the patient and to avoid costly and inefficient treatments that can potentially lead to the development of further resistances. This project proposes application of nano-optomechanical disk resonators to face this challenge. We expect to achieve ultra-sensitive and ultrafast gene-based pathogen detection with subzeptogram (10-21g) mass resolution, beating current techniques. The development of arrays of 100s of microdrum devices per chip will weigh complementary DNA strands to those immobilized on the microdrum surface, so tens of different pathogens in a sample can be identified, along with antibiotic resistances, which are also marked by mutations. The devices will be challenged with a proof-of-principle application to identify sepsis-causing pathogens from blood samples and their resistance to the most commonly used antibiotics. The proposed devices provide a large binding area to reduce the analysis time while preserving extreme sensitivity, down to a few biomolecules (DNA strands). We will be able to screen for tens of different pathogens per chip, with sensitivity good enough to target early infection stages from a standard blood extraction. This multidisciplinary and intersectorial project promotes the collaboration of well-recognized academic research groups expert in the optomechanics field and in the development of novel biosensing tools, a clinical laboratory and an industrial partner, pursuing to generate greater economic and social impact; as well as a highly effective training program for the benefit of the researcher.", "To": ["2018-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2016-11-01"], "Project_ID": ["703354"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["LANCASTER UNIVERSITY", "MEDIZINISCHE UNIVERSITAET WIEN", "POLITECNICO DI TORINO", "INSTITUT CURIE", "Bayer AG", "UNIVERSITAET BREMEN", "Janssen Pharmaceutica NV", "INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE"], "EU_Contribution": ["EUR 3 108 939,48"], "Project_Title": ["Improving Design, Evaluation and Analysis of early drug development Studies"], "Total_Cost": ["EUR 3 108 939,48"], "Country": ["United Kingdom", "Austria", "Italy", "France", "Germany", "Germany", "Belgium", "France"], "Project_ACR": ["IDEAS"], "Technology_Description": "Drug development is a long and costly process which suffers from the major shortcoming that frequently failure is often only determined during the final stage. Recently, it has been recognised that more care needs to be taken during the early stages of development to avoid going into lengthy and costly confirmatory studies with ineffective or harmful treatments. To achieve this goal it is essential to implement efficient methods for the design and analysis of such early development studies. The expertise in this area is, however, limited at the moment and adequate methodology is only partially available. Using a cross-sectorial, transnational approach, the IDEAS network brings together leading public and private sector researchers in the field with ample experience in training to educate, promote and support the future leaders in medical statistics in general and in the design and analysis of early developmental studies in particular.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations"], "From": ["2015-01-01"], "Project_ID": ["633567"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["UNIVERSITAT DE GIRONA", "UNIVERSIDAD DE MURCIA", "FUNDACIO CATALANA PER A LA RECERCA I LA INNOVACIO", "FUNDACI\u00d3N S\u00c9NECA-AGENCIA DE CIENCIA Y TECNOLOG\u00cdA DE LA REGI\u00d3N DE MURCIA", "CONSORCIO PARA LA CONSTRUCCION, EQUIPAMIENTO Y EXPLOTACION DEL CENTRO NACIONAL DE INVESTIGACION SOBRE LA EVOLUCION HUMANA", "FUNDACION CANARIA PARQUE CIENTIFICO TECNOLOGICO DE LA UNIVERSIDAD DE LAS PALMAS DE GRAN CANARIA", "UNIVERSIDAD DE OVIEDO", "CONSEJERIA DE FOMENTO Y MEDIO AMBIENTE - JUNTA DE CASTILLA Y LEON", "CONSORCIO PARA LA CONSTRUCCION EQUIPAMIENTO Y EXPLOTACION DEL LABORATORIO DE LUZ SINCROTRON", "BIOCOMUNICA'T", "INSTITUT DE RECERCA BIOMEDICA DE LLEIDA FUNDACIO PRIVADA DOCTOR PIFARRE", "UNIVERSIDAD DE EXTREMADURA", "FUNDACION MUSEO DE LA CIENCIA DE VALLADOLID", "UNIVERSIDAD DE CANTABRIA"], "EU_Contribution": ["EUR 180 000"], "Project_Title": ["European Researchers' Night: Researchers' For a Better Future"], "Total_Cost": ["EUR 345 040"], "Country": ["Spain", "Spain", "Spain", "Spain", "Spain", "Spain", "Spain", "Spain", "Spain", "Spain", "Spain", "Spain", "Spain", "Spain"], "Project_ACR": ["OurFuture"], "Technology_Description": "The OurFuture: Researchers For a Better Future proposal consists in a two years proposal with different activities that are deeply related. The first activity consists of twelve main Events on the 26th September 2014 and 25th September 2015, organised by five universities, 3 public foundations, one scientific association, one autonomic government and a scientific installation around Spain as well as a Science Museum. A second activity consists on a Drawing Competition, which will be performed before and after the both events. Also special emphasis will be done on the 2.0 tools, using games and videos edited in the previous edition of European Researchers\u2019 Night (ERN). These tools, together with the Drawing Competition, will be used to disseminate Friday Event Activities. ", "To": ["2015-10-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-NIGHT-2014 - European Researchers' Night (NIGHT)"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other", "Other", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Other", "Research Organisations", "Higher or Secondary Education Establishments", "Other", "Higher or Secondary Education Establishments"], "From": ["2014-04-01"], "Project_ID": ["633243"], "Call_for_Proposal": ["H2020-MSCA-NIGHT-2014"]}, -{"Partners": ["ISTITUTO NAZIONALE DI GEOFISICA E VULCANOLOGIA", "INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER", "HELLENIC CENTRE FOR MARINE RESEARCH", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "NATURAL ENVIRONMENT RESEARCH COUNCIL", "MARINE INSTITUTE", "UNIVERSITAET BREMEN", "INSTITUTO PORTUGUES DO MAR E DA ATMOSFERA IP", "INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU GEOLOGIE SI GEOECOLOGIE MARINA-GEOECOMAR", "SLR ENVIRONMENTAL CONSULTING(IRELAND)LIMITED", "ENGINEERING - INGEGNERIA INFORMATICA SPA"], "EU_Contribution": ["EUR 4 298 602"], "Project_Title": ["EMSO implementation and operation: DEVelopment of instrument module"], "Total_Cost": ["EUR 4 529 864,98"], "Country": ["Italy", "France", "Greece", "Spain", "United Kingdom", "Ireland", "Germany", "Portugal", "Romania", "Ireland", "Italy"], "Project_ACR": ["EMSODEV"], "Technology_Description": "The EMSODEV general objective is to catalyse the full operations of the EMSO distributed Research Infrastructure, through the development and deployment of the EMSO Generic Instrument Module (EGIM). EGIM will provide accurate, consistent, comparable, long-term measurements of ocean parameters, which are key to addressing urgent societal and scientific challenges (e.g. climate change and hazards). This will lead to an increased interoperability of EMSO nodes and to the common collection of ocean essential variable time series. ", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["INFRADEV-3-2015 - Individual implementation and operation of ESFRI projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-09-01"], "Project_ID": ["676555"], "Call_for_Proposal": ["H2020-INFRADEV-1-2015-1"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI CAGLIARI"], "EU_Contribution": ["EUR 168 277,20"], "Project_Title": ["Catastrophic Failure in Flexural Lattice Problems"], "Total_Cost": ["EUR 168 277,20"], "Country": ["Italy"], "Project_ACR": ["CAT-FFLAP"], "Technology_Description": "Currently, there is a vast amount of research activity taking place into the development of new materials having unconventional properties and the respective technologies have been opening new eras through various applications for society. This new generation of materials, or metamaterials, have led to interesting physical properties previously thought impossible such as cloaking, negative refraction and materials that contract when heated. Most of those properties are realised in the dynamic response of the material. However, in these dynamic processes uncertainty remains as to whether these metamaterials undergo feasible deformations, remaining intact. Research into the latter is limited. Understanding this phenomenon is important in developing new metamaterials. Additionally it is crucial, for example, in larger structures such as multi-span bridges, pipelines and skyscrapers exposed to earthquakes and terrorist attacks, regularly faced in Europe and their effects can be catastrophic to human life.", "To": ["2019-09-13, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-14"], "Project_ID": ["747334"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE DE LAUSANNE"], "EU_Contribution": ["EUR 175 419,60"], "Project_Title": ["Molecular evolution in the double-clonal longhorn crazy ant"], "Total_Cost": ["EUR 175 419,60"], "Country": ["Switzerland"], "Project_ACR": ["MELCA"], "Technology_Description": "The divergent selective pressures experienced by females and males often lead to the evolution of dramatic morphological, physiological and behavioural differences. Social insects hold a special place for understanding the evolution of phenotypic differences, because one sex at least is subdivided into morphologically distinct reproductive and non-reproductive (worker) castes. This research program will investigate the molecular mechanisms governing the evolution of sex (male vs female) and caste (queen vs worker) differences by studying the remarkable longhorn crazy ant Paratrechina longicornis. This species has evolved an unusual genetic system, whereby queen, male and worker phenotypes do not only result from gene expression differences, but also possess different genetic makeups. Under this system, the genomes of queens and males no longer recombine and evolve as separate entities similar to sex chromosomes. Queens are clones of their mother, males are clones of their father, and sterile workers are produced sexually through the union of queen and male genomes. The MELCA project proposes to take advantage of this double-clonal system to study how selection shapes the evolution and expression of genes involved in phenotypic differences. We will sequence the genomes and transcriptomes of double-clonal queens, males, and workers, and link patterns of gene expression with changes in rates of molecular evolution to test predictions regarding the nature of selection acting on genes involved in sex and caste differences. First, we will investigate the effects of the double-clonal system on patterns of sex-biased and allele-biased gene expression. Second, we will determine if this system leads to differences in rate of evolution for genes with sex or caste functions.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["750766"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITETET I BERGEN"], "EU_Contribution": ["EUR 208 400,40"], "Project_Title": ["Modelling Complex Networks Through Graph Editing Problems"], "Total_Cost": ["EUR 208 400,40"], "Country": ["Norway"], "Project_ACR": ["PROXNET"], "Technology_Description": "The goal of the PROXNET project, which will be realised during the mobility of Christophe Crespelle in the Algorithms group of Bergen, is to open a new way for analysing, modelling and managing complex networks, through graph editing problems.", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["749022"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF LEEDS"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Frequency Comb Spectroscopy of Temperature-dependent Reactions"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["FCSpecTRe"], "Technology_Description": "This goal of this project is to obtain a deeper, molecular level understanding of chemical reactions important to atmospheric and planetary chemistry, specifically reactions involved in the oxidation of organic sulfur molecules. A common theme to experimentally determining chemical reaction rates is to monitor the disappearance of a reactant, perhaps even under pseudo-first order conditions. An ideal experiment, however, would monitor the loss of each reactant and the appearance of each product, under known temperature and pressure conditions, in order to gain a more complete picture of the reaction. This project is a significant step towards the ideal kinetic experiment. Here, mid-infrared cavity-enhanced direct frequency comb spectroscopy (CE-DFCS), a technology used almost exclusively in the physics community, will be used as a tool in the chemistry community to spectroscopically identify reactants, transient species, and products based on their vibrational absorption spectra. This is a rapid, sensitive, broadband, and high-resolution technique, which enables reaction rates to be derived based on the simultaneous measurement of both the reactant disappearance and product appearance. Moreover, CE-DFCS will be coupled to a pulsed Laval supersonic expansion, an essentially wall-less reactor with well-characterized pressure and temperature conditions. Temperature dependent rate constants will be measured over a wide temperature range, relevant to Earth\u2019s atmosphere or even parts of the interstellar medium. This project has a strong interdisciplinary component, combining optical physics, fundamental physical chemistry, and atmospheric chemistry. This attribute arises from the significant two-way transfer of knowledge between the researcher and the Atmospheric and Planetary Chemistry group at the University of Leeds. In addition, the fellow will receive training during the tenure of the fellowship to enable her to become a successful independent scientist.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["743642"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSIDADE DE AVEIRO", "UNIVERSITAET DUISBURG-ESSEN", "SCIENCE AND TECHNOLOGY FACILITIES COUNCIL", "VILNIAUS UNIVERSITETAS", "HELMHOLTZ-ZENTRUM GEESTHACHT ZENTRUM FUR MATERIAL- UND KUSTENFORSCHUNG GMBH", "SMALLMATEK - SMALL MATERIALS AND TECHNOLOGIES LDA"], "EU_Contribution": ["EUR 814 500"], "Project_Title": ["TUneable Multiferroics based on oxygen OCtahedral Structures"], "Total_Cost": ["EUR 814 500"], "Country": ["Portugal", "Germany", "United Kingdom", "Lithuania", "Germany", "Portugal"], "Project_ACR": ["TUMOCS"], "Technology_Description": "The main objective of the project is development of new lead-free multiferroic materialshe for prospective application in forms of films and/or arranged layers in which the cross-coupling (magnetic-dipolar-elastic) can be tuned by both internal and external factors. This objective is to be achieved through preparation, investigation, and optimization of two kinds of Bi-containing oxygen-octahedral (BCOO) systems with paramagnetic ions involved: metastable perovskites and layered double hydroxides (LDHs). The characteristic feature of such materials is a possibility of supplementary control parameters in addition to temperature and external electric/magnetic field. Polarization in such metastable perovskites is easily switched by application of external pressure (or stress in the case of films). Electric and magnetic characteristics of BCOO LDHs are tuned through appropriate anion exchanges. It makes these characteristics dependent on environment conditions: humidity, pH, and presence of specific anion species. The BCOO materials of both mentioned groups are of interest as new and unusual multiferroics. No LDH materials have been considered as potential multiferroics so far, while the metastable BCOO materials proposed in this project have not been obtained before. Besides, a tuneability and high sensibility of their properties to external impacts make them promising for applications in sensors. Exploration and development of such materials require consolidation of specialists of complementary expertise in Physics, Chemistry, and Materials Science, with access to and skills in using specific and unique equipment and facilities. Therefore, formation of an interdisciplinary network of teams with different scientific culture and ensuring the effective knowledge & expertise transfer is important objective of the project. Advance in development of the BCOO multiferroics has potential market opportunities for R&D SME involved in this project.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Portugal"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["645660"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Frontiers in invasive species distribution modelling: incorporating human-associations and intraspecific niche structure to improve risk predictions."], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["InvasiveSDM"], "Technology_Description": "Biological invasions represent a major component of global change through their impacts on biodiversity, ecosystems and societies. Awareness of biological invasion impacts and the critical importance of evidence-based decision making have led to a persistent effort to understand the factors driving invasion success so as to be able to predict invasion outcomes. To this end, a range of modelling tools has been developed. Among them, species distribution models (SDMs) -phenomenological models that statistically relate observed species occurrences to environmental variables- play a critical role in invasion risk assessments. These models rely on ecological niche theory, which predicts that for recent events such as biological invasions, conservatism of the climatic niche is expected. However, recent studies have demonstrated that this approach could be hampered by apparent niche shifts in invasive ranges. Mismatches between native and invasive distributions derived from SDMs have been often interpreted as species adaptations in response to selection pressures in novel environments. However, methodological drawbacks of previous approaches fuel doubts about the biological meaning of these findings. In this project, two unresolved challenges faced by SDMs when applied to the biological invasion process will be examined: how (1) species\u2019 association with human-modified habitats in native ranges and (2) intraspecific niche variation shape the distribution of invasive species at biogeographical scales and how these effects influence the reliability of predictions of invasion risk. To accomplish these goals, I will use an interdisciplinary approach combining global bird distribution data, with molecular phylogenetic data and modern statistical and ecological analyses. The results of the project will contribute to improve prediction accuracy of biological invasions, and will also help better understand the invasion process.", "To": ["2019-07-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-15"], "Project_ID": ["752149"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["VYSOKE UCENI TECHNICKE V BRNE", "VYSOKE UCENI TECHNICKE V BRNE", "UNIVERSITAET STUTTGART"], "EU_Contribution": ["EUR 1 999 874"], "Project_Title": ["THz Frequency Rapid Scan \u2013 Electron Spin Resonance spectroscopy for spin dynamics investigations of bulk and surface materials (THz-FRaScan-ESR)"], "Total_Cost": ["EUR 1 999 874"], "Country": ["Czech Republic", "Czech Republic", "Germany"], "Project_ACR": ["THz-FRaScan-ESR"], "Technology_Description": "Current high frequency electron spin resonance (HFESR) instruments suffer from the disadvantages of being limited to a single frequency and to tiny sample volumes. The study of spin dynamics at frequencies beyond a few hundred gigahertz is currently prohibitively difficult. These limitations are now preventing progress in dynamic nuclear polarization (DNP) and preclude the implementation of zero-field quantum computing. In order to revolutionize sensitivity in nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI) by means of DNP techniques allowing to watch in real time molecular interactions or even to monitor how sophisticated systems (ribosomes) work, the HFESR methods have to be substantially improved. I will develop a novel and worldwide unique technique called broadband terahertz frequency rapid scan (FRaScan) ESR. I intend to implement this method into a working prototype, which will seamlessly span the entire frequency range from 100 GHz to 1 THz, and allow spin dynamics investigation of large samples. This revolutionary new concept based on rapid frequency sweeps will remove all the restrictions and limitations of conventional HFESR methods used nowadays. It will enable for the first time multi-frequency studies of quantum coherence also in zero magnetic field. It will lead to substantial increases in sensitivity and concurrent decrease of measurement time, thus allowing more efficient use of resources. Finally, the method will allow identification of novel DNP signal enhancement agents, ultimately leading to a step change improvement of the MRI method. It will drastically shorten MRI scan times in hospitals, greatly enhancing patient comfort together with significantly better and precise diagnoses. The method will lead to zero field quantum computers with computation power which will be never reached with conventional technology. In summary it will lead to impacts far beyond the scientific community.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Czech Republic"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["714850"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["UNIVERSIDAD DE ZARAGOZA"], "EU_Contribution": ["EUR 257 191,20"], "Project_Title": ["Wearable Cardiorespiratory Monitor"], "Total_Cost": ["EUR 257 191,20"], "Country": ["Spain"], "Project_ACR": ["WECARMON"], "Technology_Description": "The research topic of WECARMON deals with biomedical signal processing, specifically, the analysis of electrocardiogram (ECG) signals for cardiorespiratory system assessment. WECARMON\u2019s main objective is to develop novel system for early non-invasive detection of clinical destabilizations of patients with chronic respiratory diseases, e.g., chronic obstructive pulmonary disease (COPD) and asthma. Its innovative nature is based on two main tools: 1) a long-term (months) wearable ECG device which uses dry electrodes which causes no skin irritation and which are placed in a left leadless armband, and 2) signal processing techniques for estimating respiratory rate and volumes from ECG which are robust against artefacts generated by movements during daily life.", "To": ["2020-10-08, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-09"], "Project_ID": ["745755"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KAROLINSKA INSTITUTET", "KAROLINSKA INSTITUTET"], "EU_Contribution": ["EUR 2 500 000"], "Project_Title": ["Exploration and promotion of neurogenesis in the adult brain"], "Total_Cost": ["EUR 2 500 000"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["Neurogenesis"], "Technology_Description": "It is now well established that new neurons are added to certain regions of the adult brain. There is today considerable interest in the development of regenerative therapies based on modulating endogenous neurogenesis, but it is necessary to better understand these events to assess whether this is rational and realistic. ", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["695096"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["LUNDS UNIVERSITET", "LUNDS UNIVERSITET"], "EU_Contribution": ["EUR 1 203 627"], "Project_Title": ["Mathematical aspects of three-dimensional water waves with vorticity"], "Total_Cost": ["EUR 1 203 627"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["3DWATERWAVES"], "Technology_Description": "The goal of this project is to develop a mathematical theory for steady three-dimensional water waves with vorticity. The mathematical model consists of the incompressible Euler equations with a free surface, and vorticity is important for modelling the interaction of surface waves with non-uniform currents. In the two-dimensional case, there has been a lot of progress on water waves with vorticity in the last decade. This progress has mainly been based on the stream function formulation, in which the problem is reformulated as a nonlinear elliptic free boundary problem. An analogue of this formulation is not available in three dimensions, and the theory has therefore so far been restricted to irrotational flow. In this project we seek to go beyond this restriction using two different approaches. In the first approach we will adapt methods which have been used to construct three-dimensional ideal flows with vorticity in domains with a fixed boundary to the free boundary context (for example Beltrami flows). In the second approach we will develop methods which are new even in the case of a fixed boundary, by performing a detailed study of the structure of the equations close to a given shear flow using ideas from infinite-dimensional bifurcation theory. This involves handling infinitely many resonances.", "To": ["2021-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["678698"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["FAKULTET ZA MASINSTVO I GRADJEVINARSTVO U KRALJEVO UNIVERZITETA U KRAGUJEVCU", "ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA", "STUDIO PEDRINI SRL", "TOPOMATIKA TRODIMENZIONALNO SKENIRANJE, OPTICKI MJERNI SUSTAVI I RACUNALNA OBRADA DOO", "PLAMINGO DOO, COMPANY FOR DOMESTIC AND FOREIGN TRADE, PRODUCTION AND SERVICES"], "EU_Contribution": ["EUR 468 000"], "Project_Title": ["Advanced design rules for optimMAl Dynamic properties of Additive Manufacturing products"], "Total_Cost": ["EUR 468 000"], "Country": ["Serbia", "Italy", "Italy", "Croatia", "Bosnia and Herzegovina"], "Project_ACR": ["A_MADAM"], "Technology_Description": "Additive manufacturing (AM) belongs to key enabling technologies where Europe has the leading research role. The AM technologies put considerably fewer limits on shape of the manufactured objects than conventional technologies, and offer unparalleled freedom to industrial and mechanical designers. Since the AM technologies are insensitive to production scale, they put in focus knowledge and creativity of designers instead of low prices of mass production, paving the way to development of new business models. The AM technologies, therefore, represent a technology platform that may best serve Europe in its intent to develop knowledge-based economy, driven by innovation.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Serbia"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["734455"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["KATHOLIEKE UNIVERSITEIT LEUVEN"], "EU_Contribution": ["EUR 160 800"], "Project_Title": ["HOUSING DUALIZATION: DIVIDED HOUSING CAREERS AND THE FINANCIALIZATION OF HOUSING MARKETS"], "Total_Cost": ["EUR 160 800"], "Country": ["Belgium"], "Project_ACR": ["HOU-DUAL"], "Technology_Description": "Recent years have seen a transformation of housing careers. Significant homeownership declines among young adults is evident across Europe, with growing shares in rental or staying on in the parental home. These are not merely symptoms of a temporary recession, but are outcomes of fundamental changes in labour and housing markets alongside shifting state roles. Even in so-called \u2018homeowner societies,\u2019 a future of mass homeownership appears unlikely. Rather, we see increasingly divided sectors where insiders have seen sizable asset growth contrasted with significant shares shut out from the housing market. Globally, \u2018financialization\u2019 processes have been at forefront of housing market transformation. Financialization describes real forces that have progressively changed the nature of housing, through its integration with global capital flows, neoliberal re/deregulation and increasing commodification: changes that may exacerbate the translation of labour to housing divides. All this, in an era where labour inequalities have increased and housing assets have grown in importance in the face of welfare cutbacks. Given varied homeownership entry, diverging market outcomes, and intergenerational transmission, housing is clearly central to structuring inequalities. Forces of financialization have only amplified the importance of housing towards socio-economic divides. The proposal develops a theoretical and empirical understanding of how European housing is increasingly structured by insider-outsider dynamics - or housing dualization - within contexts of labour inequality and financialization. The quantitative approach is both multi-scalar and interdisciplinary. First addressing macro-level housing divides across national settings, followed by multi-level analyses into individual outcomes structured by differing national and regional contexts. The research builds on distinct literatures across: labour market dualization, comparative housing studies, and financialization.", "To": ["2019-05-22, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-23"], "Project_ID": ["750866"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["OPTOELETTRONICA ITALIA SRL", "DESTINA GENOMICA", "UNIVERSITA DEGLI STUDI DI TRENTO", "UNIVERSIDAD DE GRANADA", "MEDIZINISCHE HOCHSCHULE HANNOVER", "GENEXPLAIN GMBH", "UNIVERSIDADE FEDERAL DE SANTA CATARINA."], "EU_Contribution": ["EUR 445 500"], "Project_Title": ["microRNA biomarkers in an innovative biophotonic sensor kit for high-specific diagnosis"], "Total_Cost": ["EUR 490 500"], "Country": ["Italy", "Spain", "Italy", "Spain", "Germany", "Germany", "Brazil"], "Project_ACR": ["miRNA-DisEASY"], "Technology_Description": "Since 2001\u2019s discovery of microRNAs (miRNAs) in humans, progress in genomics and transcriptomics has increased our comprehension of gene expression regulation. miRNAs are small, noncoding RNA molecules showing huge promise as clinical biomarkers and diagnostic tools for illness and disease, as significant changes in their expression occur in response to pathological states. However, miRNA detection is still challenging nowadays, since costly, complex sample preparations and RNA amplifications are not yet reliable enough for clinical decision making. In this context, three innovative EU companies, Optoi Microelectronics - with microelectronic knowhow and manufacturing skills - DestiNA Genomics - with \u2018error free\u2019 chemical technology for microRNAs recognition \u2013 and GeneXplain \u2013 with bioinformatic capabilities - joined forces with four key academic research groups from the Universities of Trento (Italy), Granada (Spain), Hannover Medical School (Germany) and Santa Catarina (Brazil). All the parties combined their knowledge with respect to miRNA biomarkers with a particular focus on lung cancer, to develop a novel and reliable miRNA detection system for this disease. To this end, research collaborations will address the analysis of miRNAs specifically over-expressed in lung cancer, continuing experimental work already started in the past years, but with greater integration and focus.", "To": ["2019-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Italy"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2015-12-01"], "Project_ID": ["690866"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["THE UNIVERSITY OF EDINBURGH", "THE UNIVERSITY OF EDINBURGH"], "EU_Contribution": ["EUR 1 498 618"], "Project_Title": ["Defining novel mechanisms critical for colorectal tumourigenesis"], "Total_Cost": ["EUR 1 498 618"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["COLGENES"], "Technology_Description": "Cancer genome sequencing has led to a paradigm shift in our understanding of oncogenesis. It has identified thousands of genetic alterations that segregate into two groups, a small number of frequently mutated genes and a much larger number of infrequently mutated genes. The causative role of frequently mutated genes is often clear and are the focus of concerted therapeutic development efforts. The role of those infrequently mutated is often unclear and can be difficult to separate from \u2018mutational noise\u2019. Determining the relevance of low frequency mutations is important for providing a full understanding of processes driving tumourigenesis and if functionally relevant may have broader implications on the applicability of targeted therapies.", "To": ["2022-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["715782"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["UNIVERSITY OF NEWCASTLE UPON TYNE", "UNIVERSITY OF THE WEST OF ENGLAND, BRISTOL", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "LIQUIFER SYSTEMS GROUP GMBH", "EXPLORA SRL", "UNIVERSITA DEGLI STUDI DI TRENTO"], "EU_Contribution": ["EUR 3 216 555"], "Project_Title": ["Living Architecture"], "Total_Cost": ["EUR 3 216 555"], "Country": ["United Kingdom", "United Kingdom", "Spain", "Austria", "Italy", "Italy"], "Project_ACR": ["LIAR"], "Technology_Description": "Living Architecture (LIAR) is a modular bioreactor-wall, which is based on the operational principles of microbial fuel cell technology and synthetic \u2018consortia\u2019 of microbes. LIAR is conceived as a next-generation selectively-programmable bioreactor and integral component of human dwelling, capable of extracting valuable resources from waste water and air, generation of oxygen and production of proteins and fiber by manipulating consortia performance. Its operational principles are grounded in distributed sensing, decentralised autonomous information processing, high-degree of fault-tolerance and distributed actuation and reconfiguration. Applications within urban systems are examined as a form of customizable micro-agriculture for installation in domestic, public (schools, hospitals) and office environments. Such a system has far reaching impacts on the building performance (resilience, resource recycling) manufacturing and design with ecosystems.", "To": ["2019-03-31, ongoing project |"], "Meta": [""], "Topic_s": ["FETOPEN-1-2014 - FET-Open research projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2016-04-01"], "Project_ID": ["686585"], "Call_for_Proposal": ["H2020-FETOPEN-2014-2015-RIA"]}, -{"Partners": ["FUNDACIO INSTITUT CATALA DE NANOCIENCIA I NANOTECNOLOGIA", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "UNIVERSITE GRENOBLE ALPES", "ASSOCIATION POUR LA RECHERCHE ET LE DEVELOPPEMENT DES METHODES ET PROCESSUS INDUSTRIELS", "CENTRE HOSPITALIER UNIVERSITAIRE DE GRENOBLE", "MULTI CHANNEL SYSTEMS MCS GMBH", "UNIVERSITE DE GENEVE", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN", "WAVESTONE LUXEMBOURG S.A."], "EU_Contribution": ["EUR 8 359 862,50"], "Project_Title": ["High-density cortical implants for cognitive neuroscience and rehabilitation of speech using brain-computer interfaces."], "Total_Cost": ["EUR 8 648 827,89"], "Country": ["Spain", "Spain", "France", "France", "France", "Germany", "Switzerland", "United Kingdom", "Germany", "Luxembourg"], "Project_ACR": ["BrainCom"], "Technology_Description": "The goal of BrainCom is to develop a new generation of neuroprosthetic devices for large-scale and high density recording and stimulation of the human cortex, suitable to explore and repair high-level cognitive functions. Since one of the most invalidating neurospychological conditions is arguably the impossibility to communicate with others, BrainCom primarily focuses on the restoration of speech and communication in aphasic patients suffering from upper spinal cord, brainstem or brain damage. To target broadly distributed neural systems as the language network, BrainCom proposes to use novel electronic technologies based on nanomaterials to design ultra-flexible cortical and intracortical implants adapted to large-scale high-density recording and stimulation. The main challenge of the project is to achieve flexible contact of broad cortical areas for stimulation and neural activity decoding with unprecedented spatial and temporal resolution. Critically, the development of such novel neuroprosthetic devices will permit significant advances to the basic understanding of the dynamics and neural information processing in cortical speech networks and the development of speech rehabilitation solutions using innovative brain-computer interfaces. Beyond this application, BrainCom innovations will enable the study and repair of other high-level cognitive functions such as learning and memory as well as other clinical applications such as epilepsy monitoring using closed-loop paradigms. BrainCom will be carried out by a consortium assembled to foster the emergence of a new community in Europe acting towards the development of neural speech prostheses. Thanks to its high interdisciplinarity involving technology, engineering, biology, clinical sciences, and ethics, BrainCom will contribute advances to all levels of the value chain: from technology and engineering to basic and language neuroscience, and from preclinical research in animals to clinical studies in humans.", "To": ["2021-11-30, ongoing project"], "Meta": [""], "Topic_s": ["FETPROACT-01-2016 - FET Proactive: emerging themes and communities"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-12-01"], "Project_ID": ["732032"], "Call_for_Proposal": ["FETPROACT-2016"]}, -{"Partners": ["FOLKEHELSEINSTITUTTET", "NASJONALT KUNNSKAPSSENTER FOR HELSETJENESTEN"], "EU_Contribution": ["EUR 208 400,40"], "Project_Title": ["GUideline Implementation with DEcision Support systems"], "Total_Cost": ["EUR 208 400,40"], "Country": ["Norway", "Norway"], "Project_ACR": ["GUIDES"], "Technology_Description": "Healthcare based on the best available clinical evidence can lead to better quality of care. Evidence-based guidelines are potentially important instruments, but clinicians often do not adhere to them.", "To": ["2017-07-14, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Norway"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2015-07-15"], "Project_ID": ["654981"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["VRIJE UNIVERSITEIT BRUSSEL", "UNIVERSITY OF DUNDEE"], "EU_Contribution": ["EUR 160 800"], "Project_Title": ["The role of national parliaments in the Arab transformation processes"], "Total_Cost": ["EUR 160 800"], "Country": ["Belgium", "United Kingdom"], "Project_ACR": ["ARAB PARLIAMENTS"], "Technology_Description": "The research analyses the role of national parliaments in Egypt, Jordan, Morocco and Tunisia since 2011, and assesses their contributions to the political transformation processes. It diminishes an existing research gap since parliaments have received almost no consideration in \u2018Arab Spring\u2019 research yet. Semi-structured interviews in all four countries with local parliamentarians, academics, NGO representatives, diplomats and similar decision-makers will produce primary data that will be further discussed in workshops at academic institutions in Amman, Cairo, Rabat and Tunis as well as a conference at the University of Dundee. Peer-reviewed articles, open-access contributions and a monograph will disseminate findings to the public.", "To": ["2019-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-02-01"], "Project_ID": ["706113"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["POLITECNICO DI TORINO", "FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG", "UNIVERSITE DE RENNES I", "UNIVERSITA DEGLI STUDI DI PADOVA", "Ustav fyziky materialu, Akademie Ved Ceske republiky, v.v.i.", "ELEMENT MATERIALS TECHNOLOGY HITCHIN LIMITED", "COLOROBBIA CONSULTING SRL", "Nanoforce Technology Limited", "EUROPEAN THERMODYNAMICS LIMITED"], "EU_Contribution": ["EUR 3 882 899,52"], "Project_Title": ["Advanced glasses, Composites And Ceramics for High growth Industries"], "Total_Cost": ["EUR 3 882 899,52"], "Country": ["Italy", "Germany", "France", "Italy", "Czech Republic", "United Kingdom", "Italy", "United Kingdom", "United Kingdom"], "Project_ACR": ["CoACH"], "Technology_Description": "The aim of CoACH (Advanced glasses, Composites And Ceramics for High growth Industries) is to offer a multidisciplinary training in the field of high-tech GLASSES, CERAMICS and COMPOSITES based on effective and proven industry-academia cooperation. Our scientific goals are to develop advanced knowledge on glass and ceramic based materials and to develop innovative, cost-competitive, and environmentally acceptable materials and processing technologies. ", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["642557"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["THE UNIVERSITY OF SHEFFIELD", "UNIVERSITY COLLEGE LONDON", "TECHNISCHE UNIVERSITEIT EINDHOVEN", "POLITECNICO DI MILANO", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "THERENVA", "LEEDS TEST OBJECTS LIMITED", "LIFETEC GROUP BV", "ANSYS FRANCE SAS"], "EU_Contribution": ["EUR 3 700 187,28"], "Project_Title": ["VPH-Cardiovascular Simulation and Experimentation for Personalised Medical Devices"], "Total_Cost": ["EUR 3 700 187,28"], "Country": ["United Kingdom", "United Kingdom", "Netherlands", "Italy", "France", "France", "United Kingdom", "Netherlands", "France"], "Project_ACR": ["VPH-CaSE"], "Technology_Description": "VPH-CaSE is focused on state-of-the-art developments in personalised cardiovascular support, underpinned by simulation and experimentation, building on the foundations of the Virtual Physiological Human (VPH) Initiative. The Individual Research Projects of 14 ESRs provide knowledge exchange across three research clusters ", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["642612"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["UNIVERSIDADE DO PORTO", "LANCASTER UNIVERSITY", "KARLSTADS UNIVERSITET", "TECHNISCHE HOCHSCHULE KOLN", "V\u00e4rmlands l\u00e4ns landsting", "UNIVERSITEIT MAASTRICHT", "LINKOPINGS UNIVERSITET", "EDP COMERCIAL-COMERCIALIZACAO DE ENERGIA SA", "POLITECNICO DI MILANO"], "EU_Contribution": ["EUR 2 283 925,68"], "Project_Title": ["Service Design for Innovation"], "Total_Cost": ["EUR 2 283 926,12"], "Country": ["Portugal", "United Kingdom", "Sweden", "Germany", "Sweden", "Netherlands", "Sweden", "Portugal", "Italy"], "Project_ACR": ["SDIN"], "Technology_Description": "Service Design for Innovation (SDIN)-ETN aims to integrate service design and service innovation approaches that are now dispersed into an innovative research training framework; doing so leverages the creative power of service design to foster innovation. Specific objectives are: creating a mass of researchers who can drive widespread application of service design to leapfrog innovation in European organisations; and developing interdisciplinary competences in the key SDIN area and in key service sectors -ICT, public services and utilities. ", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Portugal"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2015-01-01"], "Project_ID": ["642116"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["POLITECNICO DI MILANO"], "EU_Contribution": ["EUR 244 269"], "Project_Title": ["PHOto-induced Energy flow in Bio-inspired molecular circuits probed with Ultrafast two-dimensional Spectroscopy"], "Total_Cost": ["EUR 244 269"], "Country": ["Italy"], "Project_ACR": ["PHOEBUS"], "Technology_Description": "Solar energy is forecast to cover an important fraction of the world\u2019s energy necessities over the next century. The energy captured from sunlight will be used to drive photovoltaic cells or to produce solar fuels, thus Scientists must learn how to harvest, transfer and store it efficiently. In this framework, the PHOEBUS project aims at providing the design of innovative chemical structures (molecular circuits) that can control in sophisticated ways the flow of excitation energy.", "To": ["2018-09-30, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["655059"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["PRIMA VERA S.P.A.", "ZEPHYRO SPA", "UNIVERSITAET BAYREUTH", "AFEKA - THE ACADEMIC COLLEGE OF ENGINEERING IN TEL AVIV", "POLITECNICO DI MILANO", "ATHINA-EREVNITIKO KENTRO KAINOTOMIAS STIS TECHNOLOGIES TIS PLIROFOFORIAS, TON EPIKOLNONION KAI TIS GNOSIS", "UNIVERSIDAD DE GRANADA", "ENERTECH SOLUTION SRL", "CTADVENTURE SP ZOO", "MEAZON SA", "AFEKA YISSUMIM LTD"], "EU_Contribution": ["EUR 1 206 000"], "Project_Title": ["Support Tool for Energy Efficiency pRogrammes in medical centres"], "Total_Cost": ["EUR 1 206 000"], "Country": ["Italy", "Italy", "Germany", "Israel", "Italy", "Greece", "Spain", "Italy", "Poland", "Greece", "Israel"], "Project_ACR": ["STEER"], "Technology_Description": "To meet the greenhouse gas reduction targets set by the European Commission and to reduce the reliance on imported energy sources from not-EU countries, the energy efficiency sector vitally needs basic analytical and decision support tools. This is especially true for large scale energy-consumer plants (for ex. foundries) but also for medical centres which typically (1) use large amounts of energy, (2) run a wide number of energy consuming machinery with different electrical profiles, (3) serve a weak population that may be heavily affected by energy shortages, (4) have a continuous level of service with special periodicity and peak times, and (5) have to abide to all sorts of strict regulations (for ex. special air quality requirements). ", "To": ["2018-11-30, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Italy"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2014-12-01"], "Project_ID": ["645694"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["POLITECNICO DI MILANO"], "EU_Contribution": ["EUR 168 277,20"], "Project_Title": ["Studying the bricks of microbial cities: characterization and structural properties of exopolysaccharides and their interaction with proteins and cations in anammox granular sludge"], "Total_Cost": ["EUR 168 277,20"], "Country": ["Italy"], "Project_ACR": ["POLIS"], "Technology_Description": "The anaerobic ammonium oxidation (anammox) is an innovative technology for the removal of nitrogen from wastewater (ww) saving 60% of aeration and 100% of organic carbon. Its potential application to municipal ww allow a complete redesign of the present energy-consuming into an energy-yielding ww treatment plant. Due to the slow growth rate of anammox bacteria, their retention in the system, and therefore granule stability, is the main concern of this process. Granular stability is closely related to the properties of their exopolysaccharides (PS) and their interactions with proteins and mono-divalent cations. In the proposed research integrated analytical methods (UV-visible, FT-IR, MALDI-TOF MS, NMR, (pyrolysis)GC-MS, HPLC) will be used to investigate functional PS and their fine structures, unrevealing the mechanisms involved in anammox granular sludge formation and stability. Modern rheological (AOS, LLCT and Microrheology combined with CLSM), light scattering (DLS, SLS) and microscopy techniques (AFM, FT-IR, CLSM) will be used to investigate their interactions with proteins and cations. PS will be isolated from lab- and full-scale reactors. The definition of standardized extraction (loosely/tightly bound-EPS, LB/TB-EPS) and analytical methods will bridge the existing gap for efficient and meaningful comparison of the results from this and future research. The methods set up here, will largely contribute to increase the scientific significance of PS studies in anammox granular sludge area as well as facilitate the entire biofilm research field. Studies on biofouling and biocorrosion will also benefit from the high-quality of the information and basic knowledge acquired. This research will strengthen the EU leadership in anammox granular sludge technology also improving EU scientific excellence in PS research area and provides the researcher an advanced level of multidisciplinary training, opening concrete perspectives for his career development.", "To": ["2017-11-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-12-01"], "Project_ID": ["661429"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI TRENTO"], "EU_Contribution": ["EUR 180 277,20"], "Project_Title": ["The role vision plays in shaping the representation of numbers."], "Total_Cost": ["EUR 180 277,20"], "Country": ["Italy"], "Project_ACR": ["NonVisNumCog"], "Technology_Description": "In the literature on numerical cognition, vision was for a long time assumed to play an important role in the development of number representations. In line with this idea, I recently demonstrated that congenitally blind (CB) present a qualitatively different representation of numbers by comparison to their sighted peers. In this project, I propose to further explore with fMRI techniques whether the CB qualitative different numerical representation is supported by specific cerebral reorganisation of the brain. I also propose to examine whether the qualitative different numerical representations of CB could delay the acquisition of numerical concepts in childhood. I finally propose to explore the extent to which this knowledge of the blind\u2019s numerical representation could be extended to the elaboration of a multisensory mathematics teaching program. I advocate the idea that this research program is crucial because poor mathematical competencies are common among adults and result in employment and day-to-day activities difficulties. Further research into multisensory access to numerical information could therefore lead to education benefits in teaching mathematics to young children but could also promote interventions that target specific mathematical deficits. I am uniquely suited for working on this project due to a number of parallels between the skills the proposed project requires, and the skills I possess. This includes: 1) my successful collaborations with Dr Collignon in the past; 2) good inter-personal skills; 3) my strong background in the research topic; 4) working with a variety of participant populations, and combining different methodologies. If funded, the present project will allow me to continue to explore a large overarching question by applying my pre-existing knowledge to a broader range of experimental techniques and topics - a vital skill to become an independent researcher in Europe.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["700057"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITE PARIS-SUD", "UNIVERSITE PARIS-SUD", "POLITECNICO DI MILANO"], "EU_Contribution": ["EUR 1 498 125"], "Project_Title": ["Chip-scale INtegrated Photonics for the mid-Infra REd"], "Total_Cost": ["EUR 1 498 125"], "Country": ["France", "France", "Italy"], "Project_ACR": ["INsPIRE"], "Technology_Description": "Mid-infrared (mid-IR) spectroscopy is a nearly universal way to identify chemical and biological substances, as most of the molecules have their vibrational and rotational resonances in the mid-IR wavelength range. Commercially available mid-IR systems are based on bulky and expensive equipment, while lots of efforts are now devoted to the reduction of their size down to chip-scale dimensions. The demonstration of mid-IR photonic circuits on silicon chips will benefit from reliable and high-volume fabrication to offer high performance, low cost, compact, low weight and power consumption photonic circuits, which is particularly interesting for mid-IR spectroscopic sensing systems that need to be portable and low cost. ", "To": ["2020-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-04-01"], "Project_ID": ["639107"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI TRENTO"], "EU_Contribution": ["EUR 180 277,20"], "Project_Title": ["Single-Cell Transcriptomics and Spliceosome analysis to uncover new mechanisms of neuronal vulnerability to Huntington\u2019s Disease."], "Total_Cost": ["EUR 180 277,20"], "Country": ["Italy"], "Project_ACR": ["TransSplicHD"], "Technology_Description": "Huntington\u2019s disease (HD) is neurodegenerative disease caused by a CAG repeat expansion mutation in the HTT gene. The pathological process, which ultimately leads to neuronal loss mainly in the caudate and putamen, is induced - in a truly dominant manner - by a single copy of the mutant allele. Transcriptional deregulation has becoming a prevailing feature in HD and changes at single-gene level in RNA biogenesis and aberrant alternative splicing (AS) events have been associated to neuronal vulnerability. Here, I propose to disentangle at genome-wide level the connections between mutant huntingtin expression and RNA processing, and its implications for neuronal vulnerability to death. Specifically, I propose to study alterations in RNA transcription and AS in: Aim 1. Striatal, cortical and cerebellar areas of Hdh knock-in (KI) HD accurate mouse models through global RNAseq; Aim 2. In specific medium spiny neurons (MSN) of the Drd1 or Drd2 direct and indirect pathways of Hdh KI striatum through laser capture dissection and single-cell RNAseq. ", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["706567"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["ASSOCIATION POUR LA RECHERCHE ET LE DEVELOPPEMENT DES METHODES ET PROCESSUS INDUSTRIELS", "ASSOCIATION POUR LA RECHERCHE ET LE DEVELOPPEMENT DES METHODES ET PROCESSUS INDUSTRIELS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE HOSPITALIER UNIVERSITAIRE SAINT ETIENNE - CHU"], "EU_Contribution": ["EUR 1 499 783"], "Project_Title": ["Aneurysmal Arterial Mechanics: Into the Structure"], "Total_Cost": ["EUR 1 499 783,02"], "Country": ["France", "France", "France", "France"], "Project_ACR": ["AArteMIS"], "Technology_Description": "The rupture of an Aortic Aneurysm (AA), which is often lethal, is a mechanical phenomenon that occurs when the wall stress state exceeds the local strength of the tissue. Our current understanding of arterial rupture mechanisms is poor, and the physics taking place at the microscopic scale in these collagenous structures remains an open area of research. Understanding, modelling, and quantifying the micro-mechanisms which drive the mechanical response of such tissue and locally trigger rupture represents the most challenging and promising pathway towards predictive diagnosis and personalized care of AA.", "To": ["2020-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2015-04-01"], "Project_ID": ["638804"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI TRENTO"], "EU_Contribution": ["EUR 180 277,20"], "Project_Title": ["Assembly-based discovery of uncharacterized human microbiomemembers and their tracking across individuals and time"], "Total_Cost": ["EUR 180 277,20"], "Country": ["Italy"], "Project_ACR": ["DiMeTrack"], "Technology_Description": "In this proposal we aim to expose and characterize members of the human-associated microbial dark matter and exploit the novel information to dramatically enhance the resolution of metagenomic profiling and develop accurate predictive/diagnostic tools.", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["707345"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI TRENTO"], "EU_Contribution": ["EUR 180 277,20"], "Project_Title": ["River hydraulics, morphology, and vegetation: A case for improved knowledge and numerical model capabilities"], "Total_Cost": ["EUR 180 277,20"], "Country": ["Italy"], "Project_ACR": ["River-HMV"], "Technology_Description": "The interdisciplinary knowledge and ability for river managers to effectively predict flood risks, restore rivers, and assess future alterations are currently restricted to the limited understanding of how river hydraulics, morphology, and vegetation alter a river\u2019s planform, effect sediment mobility, and control the surrounding habitats. To improve this knowledge and capabilities, this research seeks to i) use physical model flume experiments to quantify the hydraulic, morphologic, and vegetation interactions of a braided channel as well as investigate the use of manipulated channel avulsion as an innovative method to increase a river\u2019s floodplain conveyance, ii) to quantify the accuracy of a cutting-edge numerical model\u2019s simulations, and iii) to improve the numerical model\u2019s functionality. Through increased knowledge, improved model capabilities, and potentially identifying a new technique to increase a degraded river\u2019s floodplain dynamics, this research can improve the efficacy of river managers around the world. In particular, Europe could utilize the contributions of this research to help meet the ecological-morphological aspects of the Water Framework Directives and Flood Directives and to restore many of the heavily altered rivers of the European Alps.", "To": ["2017-09-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["656917"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["ASSOCIATION POUR LA RECHERCHE ET LE DEVELOPPEMENT DES METHODES ET PROCESSUS INDUSTRIELS", "ASSOCIATION POUR LA RECHERCHE ET LE DEVELOPPEMENT DES METHODES ET PROCESSUS INDUSTRIELS", "CENTRE HOSPITALIER UNIVERSITAIRE SAINT ETIENNE - CHU"], "EU_Contribution": ["EUR 1 999 396"], "Project_Title": ["Localization in biomechanics and mechanobiology of aneurysms: Towards personalized medicine"], "Total_Cost": ["EUR 1 999 396"], "Country": ["France", "France", "France"], "Project_ACR": ["BIOLOCHANICS"], "Technology_Description": "Rupture of Aortic Aneurysms (AA), which kills more than 30 000 persons every year in Europe and the USA, is a complex phenomenon that occurs when the wall stress exceeds the local strength of the aorta due to degraded properties of the tissue. The state of the art in AA biomechanics and mechanobiology reveals that major scientific challenges still have to be addressed to permit patient-specific computational predictions of AA rupture and enable localized repair of the structure with targeted pharmacologic treatment. A first challenge relates to ensuring an objective prediction of localized mechanisms preceding rupture. A second challenge relates to modelling the patient-specific evolutions of material properties leading to the localized mechanisms preceding rupture. Addressing these challenges is the aim of the BIOLOCHANICS proposal. We will take into account internal length-scales controlling localization mechanisms preceding AA rupture by implementing an enriched, also named nonlocal, continuum damage theory in the computational models of AA biomechanics and mechanobiology. We will also develop very advanced experiments, based on full-field optical measurements, aimed at characterizing localization mechanisms occurring in aortic tissues and at identifying local distributions of material properties at different stages of AA progression. A first in vivo application will be performed on genetic and pharmacological models of mice and rat AA. Eventually, a retrospective clinical study involving more than 100 patients at the Saint-Etienne University hospital will permit calibrating estimations of AA rupture risk thanks to our novel approaches and infuse them into future clinical practice. Through the achievements of BIOLOCHANICS, nonlocal mechanics will be possibly extended to other soft tissues for applications in orthopaedics, oncology, sport biomechanics, interventional surgery, human safety, cell biology, etc.", "To": ["2020-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2015-05-01"], "Project_ID": ["647067"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI TRENTO"], "EU_Contribution": ["EUR 168 277,20"], "Project_Title": ["Characterizing the Occipital Oscillatory Activity in Blindness"], "Total_Cost": ["EUR 168 277,20"], "Country": ["Italy"], "Project_ACR": ["COcOAB"], "Technology_Description": "The massive reorganization of the occipital regions as a consequence of lack of vision represents one of the most remarkable examples of the plastic potentialities of the human brain. Despite the large amount of neuroimaging evidence proving the involvement of occipital areas of blind individuals in non\u2010visual input processing, the functional role of this sensory reorganized region is still matter of intense debate. In COcOAB, we will use an underexploited neuroimaging technique in this field, magnetoencephalography (MEG), in order to study the oscillatory profile of ensembles of occipital neurons and their brain\u2010wide functional interaction patterns in blind individuals. This will allow us to gather unprecedented information about the functional relevance of non\u2010visual activity in the occipital cortex of blind individuals. Moreover, COcOAB will assess the impact of age onset and duration of visual deprivation on the occipital oscillatory activity, thus providing insights into the relationship between blindness and sensitive periods of maturation in the visual system. The groundbreaking potentials of COcOAB reside in the application of the MEG technique to the study of two experimental domains \u2014 sensory illusions and stimulation at threshold \u2014 that has been so far neglected in the field of sensory deprivation. COcOAB represents a unique testing ground to address how specific regions support perception in a mechanistic fashion in visually deprived individuals, thus challenging the current knowledge on the functionality of these reorganized regions via a highly innovative approach.", "To": ["2018-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-04-01"], "Project_ID": ["701250"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["POLITECNICO DI MILANO", "POLITECNICO DI MILANO", "ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI"], "EU_Contribution": ["EUR 1 903 330"], "Project_Title": ["Mechanobiology of nuclear import of transcription factors modeled within a bioengineered stem cell niche."], "Total_Cost": ["EUR 1 903 330"], "Country": ["Italy", "Italy", "Italy"], "Project_ACR": ["NICHOID"], "Technology_Description": "Many therapeutic applications of stem cells require accurate control of their differentiation. To this purpose there is a major ongoing effort in the development of advanced culture substrates to be used as \u201csynthetic niches\u201d for the cells, mimicking the native ones. The goal of this project is to use a synthetic niche cell culture model to test my revolutionary hypothesis that in stem cell differentiation, nuclear import of gene-regulating transcription factors is controlled by the stretch of the nuclear pore complexes. If verified, this idea could lead to a breakthrough in biomimetic approaches to engineering stem cell differentiation.", "To": ["2020-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2015-05-01"], "Project_ID": ["646990"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["POLITECNICO DI MILANO", "POLITECNICO DI MILANO"], "EU_Contribution": ["EUR 2 484 648"], "Project_Title": ["Structured Reactors with INTensified ENergy Transfer for Breakthrough Catalytic Technologies"], "Total_Cost": ["EUR 2 484 648,75"], "Country": ["Italy", "Italy"], "Project_ACR": ["INTENT"], "Technology_Description": "Critically important heterogeneous catalytic reactions for energy conversion and chemicals production have been run for several decades in fixed bed reactors randomly packed with catalyst pellets, whose operation is intrinsically limited by slow heat removal/supply. There is urgent need for a new generation of process equipment and chemical reactors to address the current quest for process intensification. I propose that a game-changing alternative is provided by structured reactors wherein the catalyst is washcoated onto or packed into structured substrates, like honeycomb monoliths, open-cell foams or other cellular materials, fabricated with highly conductive metallic (Al, Cu) materials. The goal of this project is to fully elucidate fundamental and engineering properties of such novel conductive structured catalysts, investigate new concepts for their design, manufacturing, catalytic activation and operation (e.g. 3D printing, packed foams, energy supply by solar irradiation), and demonstrate their potential for a quantum leap in the intensification of three crucial catalytic processes for the production of energy vectors: i) distributed H2 generation via efficient small-size reformers; ii) conversion of syngas to clean synthetic fuels in compact (e.g. skid-mounted) reactors; iii) production of solar H2. To this purpose I will combine advanced CFD modelling with lab-scale experimentation in order to identify the optimal structure-performance relation of existing and novel substrates, use such new knowledge to design optimized prototypes, apply unconventional additive manufacturing technologies for their production, and construct a semi-industrial tubular pilot reactor to test them at a representative scale. The project results will enable novel reactor designs based on tuning geometry, materials and configurations of the conductive internals to match the activity - selectivity demands of specific process applications, while impacting also other research areas.", "To": ["2021-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-11-01"], "Project_ID": ["694910"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["POLITECNICO DI MILANO", "POLITECNICO DI MILANO"], "EU_Contribution": ["EUR 2 500 000"], "Project_Title": ["Data-Driven Genomic Computing"], "Total_Cost": ["EUR 2 500 000"], "Country": ["Italy", "Italy"], "Project_ACR": ["GeCo"], "Technology_Description": "Next-generation sequencing technology has dramatically reduced the cost and time of reading the DNA. Huge investments are targeted to sequencing the DNA of large populations, and repositories of well-curated sequence data are being collected. Answers to fundamental biomedical problems are hidden in these data, e.g. how cancer arises, how driving mutations occur, how much cancer is dependent on environment. But genomic computing has not comparatively evolved. Bioinformatics has been driven by specific needs and distracted from a foundational approach; hundreds of methods solve individual problems, but miss the broad perspective.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["693174"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["POLITECNICO DI MILANO", "POLITECNICO DI MILANO"], "EU_Contribution": ["EUR 1 496 250"], "Project_Title": ["Structure-dependent microkinetic modelling of heterogeneous catalytic processes"], "Total_Cost": ["EUR 1 496 250"], "Country": ["Italy", "Italy"], "Project_ACR": ["SHAPE"], "Technology_Description": "Despite the fact that the catalyst structure has been an important factor in catalysis science since the discovery of structure sensitive reactions in single crystal studies, its effect on reactivity is neglected in state-of-the-art microkinetic modelling. In reality, the catalyst is dynamic by changing its structure, shape and size in response to the different conditions in the reactor. Thus, the inclusion of such effects within the framework of microkinetic modelling, albeit extremely complex, is of outmost importance in the quest of engineering the chemical transformation at the molecular level. This proposal aims to approach this grand challenge by developing a hierarchical multiscale methodology for the structure-dependent microkinetic modelling of catalytic processes in applied catalysis. In particular this challenging objective will be achieved by acting on two main fronts: ", "To": ["2021-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["677423"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["POLITECNICO DI MILANO", "POLITECNICO DI MILANO", "UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II."], "EU_Contribution": ["EUR 1 994 932,50"], "Project_Title": ["LIVING IN A FRINGE ENVIRONMENT - Investigating occupation and exploitation of desert frontier areas in the Late Roman Empire"], "Total_Cost": ["EUR 1 994 932,50"], "Country": ["Italy", "Italy", "Italy"], "Project_ACR": ["L.I.F.E."], "Technology_Description": "The scope of LIFE is to offer a complete set of archaeological and environmental data to be used to investigate Late Roman settlements along frontier desert areas and to reconstruct the underlying strategy to control the empire\u2019s desert edges. The case study is the chain of Late Roman fortified settlements that punctuate the Kharga Oasis (Egypt\u2019s Western Desert), that in the Fourth Century represented a portion of the southern boundary of the empire. All these sites, located in a remote and harsh environment, share the same architectural features and are endowed with similar agricultural installations, thus suggesting the existence of a highly motivated large-scale strategy of occupation of the region.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["681673"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["POLITECNICO DI MILANO"], "EU_Contribution": ["EUR 244 269"], "Project_Title": ["Patterning Spin-Wave reconfIgurable Nanodevices for loGics and computing."], "Total_Cost": ["EUR 244 269"], "Country": ["Italy"], "Project_ACR": ["SWING"], "Technology_Description": "Spin-waves, i.e. propagating perturbations in the spin arrangement of magnetic materials, are envisioned to revolutionize the way information is carried and processed due to their multiplexing capability and absence of Joule losses. By bringing together the complementary expertise of \u201cCUNY Advanced Science Research Center\u201d (USA) and \u201cPolitecnico di Milano (PoliMi)\u201d (Italy), the \u2018SWING\u2019 project addresses two major issues of current nanoscale magnonics: the efficient guidance of spin-waves in nanostructured materials and the study of spin-waves at the nanoscale.", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-11-01"], "Project_ID": ["705326"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["POLITECNICO DI MILANO", "POLITECNICO DI MILANO"], "EU_Contribution": ["EUR 1 499 020,97"], "Project_Title": ["Control for Orbit Manoeuvring through Perturbations for Application to Space Systems"], "Total_Cost": ["EUR 1 499 020,97"], "Country": ["Italy", "Italy"], "Project_ACR": ["COMPASS"], "Technology_Description": "Space benefits mankind through the services it provides to Earth. Future space activities progress thanks to space transfer and are safeguarded by space situation awareness. Natural orbit perturbations are responsible for the trajectory divergence from the nominal two-body problem, increasing the requirements for orbit control; whereas, in space situation awareness, they influence the orbit evolution of space debris that could cause hazard to operational spacecraft and near Earth objects that may intersect the Earth. However, this project proposes to leverage the dynamics of natural orbit perturbations to significantly reduce current extreme high mission cost and create new opportunities for space exploration and exploitation.", "To": ["2021-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-08-01"], "Project_ID": ["679086"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI TRENTO", "UNIVERSITA DEGLI STUDI DI TRENTO"], "EU_Contribution": ["EUR 1 472 502"], "Project_Title": ["Cortical Representation of Abstract Semantic Knowledge"], "Total_Cost": ["EUR 1 472 502"], "Country": ["Italy", "Italy"], "Project_ACR": ["CRASK"], "Technology_Description": "The study of semantic memory considers a broad range of knowledge extending from basic elemental concepts that allow us to recognise and understand objects like \u2018an apple\u2019, to elaborated semantic information such as knowing when it is appropriate to use a Wilcoxon Rank-Sum test. Such elaborated semantic knowledge is fundamental to our daily lives yet our understanding of the neural substrates is minimal. The objective of CRASK is to advance rapidly beyond the state-of-the-art to address this issue. CRASK will begin by building a fundamental understanding of regional contributions, hierarchical organisation and regional coordination to form a predictive systems model of semantic representation in the brain. This will be accomplished through convergent evidence from an innovative combination of fine cognitive manipulations, multimodal imaging techniques (fMRI, MEG), and advanced analytical approaches (multivariate analysis of response patterns, representational similarity analysis, functional connectivity). Progress will proceed in stages. First the systems-level network underlying our knowledge of other people will be determined. Once this is accomplished CRASK will investigate general semantic knowledge in terms of the relative contribution of canonical, feature-selective and category-selective semantic representations and their respective roles in automatic and effortful semantic access. The systems-level model of semantic representation will be used to predict and test how the brain manifests elaborated semantic knowledge. The resulting understanding of the neural substrates of elaborated semantic knowledge will open up new areas of research. In the final stage of CRASK we chart this territory in terms of human factors: understanding the role of the representational semantic system in transient failures in access, neural factors that lead to optimal encoding and retrieval and the effects of ageing on the system.", "To": ["2020-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-05-01"], "Project_ID": ["640594"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["CONSIGLIO NAZIONALE DELLE RICERCHE", "UNIVERSIDAD DE MALAGA", "TECHNISCHE UNIVERSITAT DARMSTADT", "UNIVERSITA DEGLI STUDI DI TRENTO", "UNIVERSITY OF KENT", "BRITISH TELECOMMUNICATIONS PUBLIC LIMITED COMPANY", "ATOS SPAIN SA"], "EU_Contribution": ["EUR 3 882 227,76"], "Project_Title": ["European Network for Cyber-security"], "Total_Cost": ["EUR 3 882 227,76"], "Country": ["Italy", "Spain", "Germany", "Italy", "United Kingdom", "United Kingdom", "Spain"], "Project_ACR": ["NeCS"], "Technology_Description": "The European Network for Cybersecurity (NECS) was formed in response to the increased need of highly qualified experts able to cope with all the aspects of the European cybersecurity strategy that is currently under implementation.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-09-01"], "Project_ID": ["675320"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["UNIVERSITY OF LEEDS", "TOSHIBA RESEARCH EUROPE LIMITED", "UNIVERSIDAD DE VIGO", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSITA DEGLI STUDI DI PADOVA", "HEINRICH-HEINE-UNIVERSITAET DUESSELDORF", "UNIVERSITE DE GENEVE", "ID QUANTIQUE SA", "INSTITUT MINES-TELECOM", "UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6"], "EU_Contribution": ["EUR 3 924 884,52"], "Project_Title": ["Quantum Communications for ALL"], "Total_Cost": ["EUR 3 924 884,52"], "Country": ["United Kingdom", "United Kingdom", "Spain", "France", "Italy", "Germany", "Switzerland", "Switzerland", "France", "France"], "Project_ACR": ["QCALL"], "Technology_Description": "Quantum Communications for ALL (QCALL) endeavors to take the next necessary steps to bring the developing quantum technologies closer to the doorsteps of end users. Quantum communications (QC) is well-known for its offering ultra-secure cryptographic key-exchange schemes\u2014resilient to any future technological advancement. QCALL will empower a nucleus of researchers in this area to provide secure communications in our continent and, in the long run, to our connections worldwide. With the large scale violations of privacy in the EU exchange of information, this is a crucial moment to pursue this objective. By covering a range of projects, with short, mid, and long-term visions, and using a balanced and multifaceted training programme, QCALL trains a cadre of highly qualified interdisciplinary workforce capable of shaping the R&D section of the field, hence accelerating its widespread adoption. This will ensure that EU will remain at the frontier of research on secure communications and advanced QC systems and devices. In QCALL, we explore the challenges of integrating quantum and classical communication networks; this will be essential in providing cost-efficient services. We experimentally examine and theoretically study new protocols by which network users can exchange secure keys with each other. We investigate disruptive technologies that enable wireless access to such quantum networks, and develop new devices and protocols that enable multi-party QC. Our meticulously planned training programme includes components from shared taught courses through to scientific schools and complementary-skill workshops, supplemented by secondment opportunities and innovative outreach and dissemination activities. This will create a structured model for doctoral training in EU that will last beyond the life of the project, so will the industry-academic collaborations that are essential to the development of the disruptive technologies that will make QC available to ALL.", "To": ["2020-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-12-01"], "Project_ID": ["675662"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["UNIVERSITAT AUTONOMA DE BARCELONA", "UNIVERSITAT AUTONOMA DE BARCELONA"], "EU_Contribution": ["EUR 1 453 868"], "Project_Title": ["Green Locally Unwanted Land Uses"], "Total_Cost": ["EUR 1 453 868"], "Country": ["Spain", "Spain"], "Project_ACR": ["GREENLULUS"], "Technology_Description": "This project examines the role played by the restoration and creation of environmental amenities in the redistribution of urban quality of life. Since no large-scale study has been conducted to measure if greener cities are less racially and socially equitable, I will analyze whether greening projects tend to increase environmental inequalities in 40 cities in the US and Europe and under which conditions such projects can address equity concerns. First, the study will a) develop a new method (an index) to quantify the racial and social impact of greening projects and to compare cities\u2019 performance with each other; b) provide a spatial and quantitative analysis of neighborhood demographic, real estate, and environmental data; and c) apply the index methodology on a unique ranking of cities. Second, my research will analyze the response of private investors to the greening projects and identify the impact of new development projects proposed, approved, and implemented during or upon the completion of greening projects on the neighborhood socio-demographic characteristics. I will assess the extent to which development projects seem to encourage and/or accelerate gentrification, as such projects have been shown to be signs of residents\u2019 exclusion. Additionally, this study will qualitatively analyze cases of community mobilization developed in response to new environmental amenities, through fieldwork in 16 critical neighborhoods (one neighborhood case per city) among the 40 cities. Last, this study will use qualitative methods to analyze the policies and measures that municipalities develop to address exclusion in \u201cgreening\u201d neighborhoods. This groundbreaking longitudinal, systematic, in-depth, and large-scale project in the field of environmental justice will lead to a paradigm shift by hypothesizing that the social and racial inequities present in sustainability projects make green amenities Locally Unwanted Land Uses (LULUs) for poor residents and people of color.", "To": ["2021-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["678034"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["POLITECNICO DI MILANO", "POLITECNICO DI MILANO"], "EU_Contribution": ["EUR 1 887 500"], "Project_Title": ["Exploring the New Science and engineering unveiled by Ultraintense ultrashort Radiation interaction with mattEr"], "Total_Cost": ["EUR 1 887 500"], "Country": ["Italy", "Italy"], "Project_ACR": ["ENSURE"], "Technology_Description": "With the ENSURE project I aim at attaining ground-breaking results in the field of superintense laser-driven ion acceleration, proposing a multidisciplinary research program in which theoretical, numerical and experimental research will be coherently developed in a team integrating in an unprecedented way advanced expertise from materials engineering and nanotechnology, laser-plasma physics, computational science. The aim will be to bring this topic from the realm of fundamental basic science into a subject having realistic engineering applications.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["647554"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["POLITECNICO DI MILANO", "POLITECNICO DI MILANO"], "EU_Contribution": ["EUR 1 822 500"], "Project_Title": ["Very fast Imaging by Broadband coherent RAman"], "Total_Cost": ["EUR 1 822 500"], "Country": ["Italy", "Italy"], "Project_ACR": ["VIBRA"], "Technology_Description": "The VIBRA project aims at developing an innovative microscope for real-time non-invasive imaging of cells and tissues, which promises to have a revolutionary impact on several fields of biology and medicine. Chemically specific vibrational signatures of molecules enable their direct structural characterization. Reliable and quantitative endogenous bio-markers can be established, e.g., to follow cell differentiation and to identify crucial properties of tissues (malignant vs benign phenotype of a tumour). In this way neoplasms can be located and their borders with normal tissue traced for surgery. ", "To": ["2020-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-06-01"], "Project_ID": ["648615"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["TECHNISCHE UNIVERSITAET MUENCHEN"], "EU_Contribution": ["EUR 214 828,20"], "Project_Title": ["Non-Leptonic Three-Body B Decays: Theory and Phenomenology"], "Total_Cost": ["EUR 214 828,20"], "Country": ["Germany"], "Project_ACR": ["NIOBE"], "Technology_Description": "Tests of the Standard Model (SM) of Particle Physics and the search for New Physics (NP) is a central issue in the European program in High-Energy Physics. Weak decays of heavy hadrons have a unique potential for the extraction of SM parameters, the study of CP violation, and the search for NP. Among these, decays of B mesons into three final hadrons are of huge phenomenological interest. They have been studied experimentally at B factories and at the LHC, and will be a cornerstone in the physics program at Belle-II. However, the theoretical basis for such processes has yet not been developed. Through this project, we will establish the theoretical grounds for the description of non-leptonic three-body B decays, from basic principles to phenomenological applications.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["700525"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["DANMARKS TEKNISKE UNIVERSITET", "KATHOLIEKE UNIVERSITEIT LEUVEN", "UNIVERSITAET BREMEN", "INSTITUTTET FOR PRODUKTUDVIKLING", "POLITECNICO DI MILANO", "UNIVERSITY OF STRATHCLYDE", "UNIVERSITY OF BRADFORD", "TECHNISCHE UNIVERSITAET CHEMNITZ", "THE UNIVERSITY OF NOTTINGHAM"], "EU_Contribution": ["EUR 3 446 156,52"], "Project_Title": ["European Training Network on \u201cProcess Fingerprint for Zero-defect Net-shape MICROMANufacturing\u201d"], "Total_Cost": ["EUR 3 446 156,52"], "Country": ["Denmark", "Belgium", "Germany", "Denmark", "Italy", "United Kingdom", "United Kingdom", "Germany", "United Kingdom"], "Project_ACR": ["MICROMAN"], "Technology_Description": "The continuous trend towards miniaturization and multi-functionality embedded in products and processes calls for an ever increasing innovation, research and development within the European manufacturing sector. A necessary condition for the European productive sector to be at the global forefront of technology, ensuring job creation and sustainable growth, is to have access to innovative, entrepreneurial, highly skilled research engineers in the fields of micro manufacturing and micro product/process development. The MICROMAN ITN will provide world excellent research training to 13 ESR in the field of micro manufacturing proposing: (1) innovative technological solutions for high quality and high throughput micro production (micro manufacturing process fingerprint, zero-defect net-shape micro manufacturing) for the micro manufacturing industry; (2) cutting edge inter-disciplinary training in different domains (\u00b5-polymer moulding, \u00b5-metal forming, \u00b5-extrusion, \u00b5-tooling technologies, \u00b5-product metrology, \u00b5-manufacturing process metrology); (3) validation of different micro manufacturing processes by integration into process chains for the production of micro component for the bio-medical, health-care, machine tool, pharmaceutical, quality control sectors. The training strategy is based on the 50-30-20 principle, in which each single ESR will develop a core technical competence, a complementary technical competence, and a general technical competence in all domains addressed by the project with a research effort proportional to the 50%-30%-20% of the total effort. An all-round, comprehensive yet specialized, training in micro manufacturing will be ensured. Specific training on project engineering research management and entrepreneurship completes the training and provides the ESR the required skills to effectively contribute to the competitiveness of the European micro manufacturing industry, and in turn to job creation and well-being of the European society.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["674801"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["POLITECNICO DI MILANO", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "UNIVERSIDADE DO PORTO", "INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE", "CINECA CONSORZIO INTERUNIVERSITARIO", "VYSOKA SKOLA BANSKA - TECHNICKA UNIVERZITA OSTRAVA", "DOMPE FARMACEUTICI SPA", "SYGIC AS"], "EU_Contribution": ["EUR 3 115 251"], "Project_Title": ["AutoTuning and Adaptivity appRoach for Energy efficient eXascale HPC systems"], "Total_Cost": ["EUR 3 115 251,25"], "Country": ["Italy", "Switzerland", "Portugal", "France", "Italy", "Czech Republic", "Italy", "Slovakia"], "Project_ACR": ["ANTAREX"], "Technology_Description": "Energy-efficient heterogeneous supercomputing architectures need to be coupled with a radically new software stack capable of exploiting the benefits offered by the heterogeneity at all the different levels (supercomputer, job, node) to meet the scalability and energy efficiency required by Exascale supercomputers.", "To": ["2018-08-31, ongoing project |"], "Meta": [""], "Topic_s": ["FETHPC-1-2014 - HPC Core Technologies, Programming Environments and Algorithms for Extreme Parallelism and Extreme Data Applications"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-09-01"], "Project_ID": ["671623"], "Call_for_Proposal": ["H2020-FETHPC-2014"]}, -{"Partners": ["POLITECNICO DI MILANO", "POLITECNICO DI MILANO"], "EU_Contribution": ["EUR 149 625"], "Project_Title": ["Mid Infrared SpectrometerS by an Innovative Optical iNterferometer"], "Total_Cost": ["EUR 149 625"], "Country": ["Italy", "Italy"], "Project_ACR": ["MISSION"], "Technology_Description": "The MISSION projects aims at bringing to the market a revolutionary concept of mid-infrared (MIR) interferometer, for a new generation of compact, low-cost, rugged spectrometers. Many applications of chemistry, materials science and life sciences require analysis and identification of substances based on their vibrational absorption spectra in the MIR. Time domain vibrational spectroscopy techniques such as FTIR and 2DIR are based on the use of an optical Michelson interferometer, producing two identical phase-shifted replicas of the input beam. Phase determination is technically very challenging and requires tracking with an auxiliary laser beam and in some cases the use of active stabilization approaches, with feedback control on the interferometer arms, greatly increasing device complexity. We have recently introduced a new optical interferometer, called TWINS, which exploits material birefringence to impose highly controllable delays. TWINS has the advantages of being inherently phase stable, compact, rugged, highly reproducible and potentially low cost. The TWINS concept, for which a patent has been filed, was successfully demonstrated in the visible and the MIR spectral ranges. It is the goal of the MISSION project to unleash the innovation potential of TWINS, by developing, technically validating and bringing to the market a TWINS-based MIR interferometer, paving the way to a new generation of compact and low-cost analytical instruments for a wide range of applications. We have identified a suitable material with broad MIR transparency and huge birefringence: calomel. The MISSION project aims at: i) building a TWINS device based on calomel; ii) demonstrating its application to MIR spectroscopy; and iii) turning it into a commercial product, to be sold either as stand-alone device or as part of a spectroscopic instrument. We expect that TWINS will significantly reduce the cost of MIR interferometers, thus widely broadening their application portfolio.", "To": ["2016-11-30, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2014 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-06-01"], "Project_ID": ["665635"], "Call_for_Proposal": ["ERC-2014-PoC"]}, -{"Partners": ["ASSOCIATION POUR LA RECHERCHE ET LE DEVELOPPEMENT DES METHODES ET PROCESSUS INDUSTRIELS", "ASSOCIATION POUR LA RECHERCHE ET LE DEVELOPPEMENT DES METHODES ET PROCESSUS INDUSTRIELS"], "EU_Contribution": ["EUR 149 673"], "Project_Title": ["Exploitation of Organic Electrochemical Transistors for Biological Ionsensing \u2013 Proof Of Concept"], "Total_Cost": ["EUR 149 673"], "Country": ["France", "France"], "Project_ACR": ["IONOSENSE-POC"], "Technology_Description": "The IONOSENSE-POC project proposes a novel solution to enable label-free, electronic monitoring of live cells in vitro, using innovative organic bioelectronic technology. The device, the organic electrochemical transistor (OECT), integrated with live cells forming a tissue, has been shown to accurately assess the integrity of the cells, providing dynamic, highly sensitive measurements after exposure to toxins/pathogens. Validation against traditional, optical methods, or commercially available electronic monitoring equipment demonstrated the OECT to have equal or improved sensitivity and temporal resolution. As an added bonus, the OECT is fabricated using conducting polymers, which are not only amenable to low cost processing techniques, but are also optically transparent, yielding devices compatible with high resolution imaging techniques, of critical importance to life scientists. In the POC project, we propose to take this extremely promising technological breakthrough developed in an academic environment, and transition it to a prototype suitable for future commercialization. In parallel, the appropriate steps will be taken necessary to ascertain the market niche(s), initially identified as being in the areas of Biomems targeted for diagnostics/drug discovery. Finally, an adapted exploitation strategy will be developed to best suit the technology developed during the IONOSENSE project. The team assembled to execute the project is extremely committed to the commercialization venture, in particular due to significant feedback from industrial partners (potential endusers) from such diverse biomedical applications as the cosmetics industry, neurotoxicology, electrophysiology instrumentation developers, drug development companies etc. The success of this POC project will have broad ranging, highly positive impacts for society in the EU and further, due to reduction of experimentation on animals, improved healthcare outcomes, and economic development to name a few.", "To": ["2016-09-30, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2014 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2015-04-01"], "Project_ID": ["665725"], "Call_for_Proposal": ["ERC-2014-PoC"]}, -{"Partners": ["POLITECNICO DI MILANO", "POLITECNICO DI MILANO"], "EU_Contribution": ["EUR 1 998 113,12"], "Project_Title": ["REsistive-Switch CompUting bEyond CMOS"], "Total_Cost": ["EUR 1 998 113,12"], "Country": ["Italy", "Italy"], "Project_ACR": ["RESCUE"], "Technology_Description": "Digital computers rely today on CMOS (complementary metal-oxide-semiconductor) technology, which improves its performance every generation thanks to the Moore\u2019s law of downscaling. As CMOS transistor size approaches few nm, alternative logic switches with better scaling capability must be identified to prolong Moore\u2019s law beyond CMOS. Among the emerging switching concepts, resistive switching (RS) devices can change their resistance by electrically-induced redox reactions. RS provides the basis for the resistive memory (ReRAM) technology which is currently investigated as future computer memory and storage technology. The objective of this project is to design, develop and demonstrate a novel computing paradigm based on RS devices. The project will pursue this objective at 3 levels of increasing complexity, namely the device fabrication, the design of new logic gates and the demonstration of computing circuits. RS logic will be finally compared to CMOS and other approaches to identify the strength and the potential applications of RS logic in the computing scenario.", "To": ["2020-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-08-01"], "Project_ID": ["648635"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI TRENTO", "UNIVERSITA DEGLI STUDI DI TRENTO"], "EU_Contribution": ["EUR 1 996 428"], "Project_Title": ["Synthetic Lethal Phenotype Identification through Cancer Evolution Analysis"], "Total_Cost": ["EUR 1 996 428"], "Country": ["Italy", "Italy"], "Project_ACR": ["SPICE"], "Technology_Description": "Prostate cancer (PCA) is a genetically heterogeneous disease. Advances in targeted hormonal therapy (second generation anti-androgens) have led to more effective management of castration-resistant prostate cancer (CRPC). Despite these highly potent drugs, disease recurs with new genomic and epigenetic alterations. In this ERC proposal, I will leverage my expertise in cancer genomics and a new computational methodology to unravel the landscape of lethal PCA, with a focus on determining the Achilles\u2019 heel of these aggressive tumours. In Aim 1, I will take advantage of DNA sequencing data from over 1000 patient-derived tumour samples and use highly innovative mathematical algorithms to create a detailed evolution chart for each tumour and identify driver events leading to CRPC. After nominating candidate drivers, we propose testing 10 using in vitro gain- and loss-of-function validations experiments (i.e., CRISPR/Cas9, shRNA, and Tet-On assays) in PCA cell lines using migration, invasion, and cell cycle as readouts. In Aim 2, I will focus on genomic events that occur in recalcitrant CRPC, positing that genetic alterations occurring prior or secondary to treatment harbour clues into resistance. In vitro validations will be performed on the top 10 biomarkers. In Aim 3, I will nominate synthetic lethality combinations by mining CRPC genomic data taken from Stand Up 2 Cancer CRPC clinical trials. I will prioritize mutually exclusive genomic alterations in genes for which approved drugs exist. The top 5-10 candidates will be validated in a prostate lineage-specific manner. In summary, this ERC proposal will leverage my many years of expertise in PCA genomics and emerging public and private CRPC datasets to uncover driver mutations that will enhance our understanding of recalcitrant CRPC. Successful completion of this study should lead to novel treatment approaches for CRPC and to a computational model that may transform our approach to evaluating other cancers.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["648670"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI TRENTO"], "EU_Contribution": ["EUR 180 277,20"], "Project_Title": ["Alpine lakes benthic viral community structure and diversity: a metagenomic and ecological approach"], "Total_Cost": ["EUR 180 277,20"], "Country": ["Italy"], "Project_ACR": ["metaVir-Alp"], "Technology_Description": "Viruses are a key and yet neglected component of freshwater ecosystems. By impacting bacterial communities they influence evolutionary dynamics, mineralisation processes, energy transfer across trophic levels and greenhouse gas emission. Nonetheless, they are among the least understood organisms.", "To": ["2018-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-11-01"], "Project_ID": ["704603"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITAET GRAZ", "SVEUCILISTE U ZAGREBU FAKULTET ELEKTROTEHNIKE I RACUNARSTVA", "SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO SANT'ANNA", "UNIVERSITE LIBRE DE BRUXELLES", "ASSOCIATION POUR LA RECHERCHE ET LE DEVELOPPEMENT DES METHODES ET PROCESSUS INDUSTRIELS", "CORILA - CONSORZIO PER IL COORDINAMENTO DELLE RICERCHE INERENTI AL SISTEMA LAGUNARE DI VENEZIA", "CYBERTRONICA UG (HAFTUNGSBESCHRANKT) GMBH"], "EU_Contribution": ["EUR 3 987 650"], "Project_Title": ["SUBMARINE CULTURES PERFORM LONG-TERM ROBOTIC EXPLORATION OF UNCONVENTIONAL ENVIRONMENTAL NICHES"], "Total_Cost": ["EUR 3 987 650,75"], "Country": ["Austria", "Croatia", "Italy", "Belgium", "France", "Italy", "Germany"], "Project_ACR": ["subCULTron"], "Technology_Description": "subCULTron aims for achieving long-term autonomy in a learning, self-regulating, self-sustaining underwater society/culture of robots in a high-impact application area: Venice, Italy. Our heterogeneous system consists of 3 different agent types: On the sea-ground, artificial mussels are the collective long-term memory of the system, allowing information to stay beyond the runtime of other agents, thus allowing to continue learning from previously learned states. These mussels monitor the natural habitat, including biological agents like algae, bacterial incrustation and fish. On the water surface, artificial lilypads interface with the human society, delivering energy and information influx from ship traffic or satellite data. Between those two layers, artificial fish move/monitor/explore the environment and exchange info with the mussels and lilypads. Artificial mussels are a novel class of underwater agents. We aim to push forward the edge of knowledge with novel sensors (electric sense/electro-communication), novel bio-inspired algorithms (underwater hives) and novel energy harvesting in underwater scenarios. We will improve the world\u2019s record for swarm-size in autonomous collective underwater robotics by almost one order of magnitude. Our application field is a human- and animal-co-inhabited real-world environment of high impact: Venice canals & lagoon. These habitats are highly dynamic and structured, expected to be reflected by a spatial self-structuring of our mussel population. These sub-populations locally perform memetic/ cultural learning algorithms on their specific local data. Thus our cultural evolution algorithms will promote sub-culture development, similar to the human society that does the same above the water level in parallel. Overall, we aim for an artificial society underneath the water-surface to the service of a human society above the water.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["FETPROACT-2-2014 - Knowing, doing, being: cognition beyond problem solving"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-04-01"], "Project_ID": ["640967"], "Call_for_Proposal": ["H2020-FETPROACT-2014"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI TRENTO"], "EU_Contribution": ["EUR 168 277,20"], "Project_Title": ["A New View on Real Actions: Neural Mechanisms of Visuo-Motor Transformations"], "Total_Cost": ["EUR 168 277,20"], "Country": ["Italy"], "Project_ACR": ["BraIn Action"], "Technology_Description": "The goal of this project proposal is to investigate the neural mechanisms of motor control in relation to primary visual function in healthy adults. In particular, I will examine the role of primary visual cortex (V1) in action planning and execution by using a combination of neuroimaging, neurostimulation and behavioural techniques.", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["703597"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI TRENTO", "UNIVERSITA DEGLI STUDI DI TRENTO"], "EU_Contribution": ["EUR 149 943,75"], "Project_Title": ["SILKENE: Bionic silk with graphene or other nanomaterials spun by silkworms"], "Total_Cost": ["EUR 149 943,75"], "Country": ["Italy", "Italy"], "Project_ACR": ["SILKENE"], "Technology_Description": "\"The project aims at designing, developing, scaling-up and optimizing a pre-industrial process towards the mass production of \u201csilkene\u201d, a bionic silk fiber reinforced with graphene, or other nanomaterials such as nanotubes, directly spun by silkworms. The idea is simply based on nanomaterial ingestion and subsequent \u201csilkene\u201d spinning by silkworms. Silkene is expected to be significantly stronger and tougher that its natural counterpart. Since silk produced by silkworms has already impacted our society, the impact of SILKENE project could also be significant. The process under consideration should in this project be technically verified, optimized and taken to a pre-commercial stage, for applications in industrial sectors such as smart or high-performance technical fibers, textiles, and related reinforced composites. The concept has been already preliminarily (see http://arxiv.org/abs/1504.06751) demonstrated at the laboratory scale with spiders, within our ERC Starting Grant \"Bio-inspired Hierarchical Super Nanomaterials\" (BIHSNAM).\"", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2015 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["693670"], "Call_for_Proposal": ["ERC-2015-PoC"]}, -{"Partners": ["INSTITUT MINES-TELECOM", "ECOLE NATIONALE SUPERIEURE DES MINES DE SAINT-ETIENNE"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Smart electroactive 3D models of osteoregeneration"], "Total_Cost": ["EUR 173 076"], "Country": ["France", "France"], "Project_ACR": ["SMART-BONE"], "Technology_Description": "In the European Union alone, the annual number of bone fractures is projected to reach 4.5 million in 2025. Despite the advances in implant technology, grafts prepared using bone extracted from the patient to fill the bone defect are the only material reported so far to retain any significant efficacy in sustaining new bone formation. However, the aging worldwide population and increased life expectancy call for a different answer to the growing need for effective implants for bone fracture healing. ", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["704175"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI TRENTO", "POLSKO JAPONSKA WYZSZA SZKOLA TECHNIK KOMPUTEROWYCH PJWSTK", "Ente Ospedaliero Cantonale"], "EU_Contribution": ["EUR 931 500"], "Project_Title": ["Social Participation for improving emotional, mental, and physical wellbeing in independently living older adults"], "Total_Cost": ["EUR 931 500"], "Country": ["Italy", "Poland", "Switzerland"], "Project_ACR": ["DREAM"], "Technology_Description": "The combination of longer life expectancy, evolving socio-economical norms and conditions, and new technologies are dramatically changing life after retirement, and not always for the better. In more and more countries, pensioners find themselves with many years in front of them, some of them likely characterized by reduced physical and cognitive abilities. For older adults, this span of time out of the workforce was traditionally devoted to the role (and source of great joy) of caring for grandchildren. However, this role is fading out because of increased mobility of children, which often live far away for work, love, or other reasons, leading to an increase of loneliness and social isolation. This project aims at rethinking long life and understanding the socio-economical context that can make this period of life more exiting and attractive.", "To": ["2019-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2016-02-01"], "Project_ID": ["690962"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["UNINOVA-INSTITUTO DE DESENVOLVIMENTO DE NOVAS TECNOLOGIAS-ASSOCIACAO", "NOVA ID FCT - ASSOCIACAO PARA A INOVACAO E DESENVOLVIMENTO DA FCT", "ECOLE NATIONALE SUPERIEURE DES MINES D'ALES", "INSTITUT MINES-TELECOM", "LAPPEENRANNAN TEKNILLINEN YLIOPISTO", "DONETSK INSTITUTE FOR PHYSICS AND ENGINEERING NAMED AFTER O.O. GALKIN OF THE NATIONAL ACADEMY OF SCIENCESS OF UKRAINE", "SOLENE-R", "Blueorizon - Projectos de Engenharia, Unipessoal, Lda"], "EU_Contribution": ["EUR 873 000"], "Project_Title": ["Advanced Humidity to Electricity Converter"], "Total_Cost": ["EUR 873 000"], "Country": ["Portugal", "Portugal", "France", "France", "Finland", "Ukraine", "France", "Portugal"], "Project_ACR": ["HUNTER"], "Technology_Description": "The HUNTER project will develop revolutionary power devices that convert humidity into electrical charge (hygroelectricity), thereby contributing to the European technology and creativity through joint R&D and R&I multisectorial and international cooperation activities supported by knowledge sharing. The devices will harvest electricity from atmospheric humidity and supply a current, such as solar cells capture sunlight and generate electrical power. The successful realization of the project is assured by implementing a coordinated network of knowledge sharing in materials science, physics and chemistry; by solidifying the state-of-the-art understanding in nanoelectronics and by applying bottom-up nanoengineering approaches via an international and inter-sector collaboration of highly qualified researchers from Portugal, France, Finland, Ukraine, Belarus and USA. Both technological (nanoelectronic device fabrication) and fundamental (charge transport mechanisms) issues will be assessed by this multidisciplinary consortium.", "To": ["2019-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Portugal"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-12-01"], "Project_ID": ["691010"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["UNIVERSITAT ZU LUBECK", "POLITECNICO DI MILANO", "OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN"], "EU_Contribution": ["EUR 823 500"], "Project_Title": ["Approximation Methods for Molecular Modelling and Diagnosis Tools"], "Total_Cost": ["EUR 823 500"], "Country": ["Germany", "Italy", "Austria"], "Project_ACR": ["AMMODIT"], "Technology_Description": "This proposal brings together research teams from the EU (Germany, Italy, and Austria) and the Ukraine (Kyiv, Donezk) in the area of applied mathematics with emphasis on medical and life science applications. ", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2015-08-01"], "Project_ID": ["645672"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["LABORATORIO EUROPEO DI SPETTROSCOPIE NON LINEARI", "FUNDACIO INSTITUT DE CIENCIES FOTONIQUES", "UNIWERSYTET JAGIELLONSKI", "UNIVERSITA DEGLI STUDI DI TRENTO", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 2 386 875"], "Project_Title": ["Quantum simulations of insulators and conductors"], "Total_Cost": ["EUR 2 774 375"], "Country": ["Italy", "Spain", "Poland", "Italy", "Switzerland", "France"], "Project_ACR": ["QUIC"], "Technology_Description": "It is now accepted that the conducting or insulating nature of matter is based on various separate ingredients (e.g. disorder, interactions, band filling, dimensionality, topology, etc.). However, their complex interplay is still beyond our understanding because experiments are very difficult and numerical calculations are often inefficient, even for supercomputers. In QUIC we want to achieve a breakthrough in the understanding of the fundamental mechanisms governing insulators and conductors by using quantum simulators, i.e. quantum computers of special purpose, based on fully controllable ultracold gases. In an experiment-theory enterprise, we will engineer several different kinds of such synthetic quantum matter, where we can isolate and study quantitatively the quantum phenomena and phases. We will not only study the physics of real systems, such as disordered and strongly-correlated superconductors and superfluids, but we will also create systems that do not exist so far in nature, such as topological phases in graphene-like lattices. QUIC combines for the first time advanced manipulation techniques of ultracold atomic gases, innovative theoretical ideas of condensed-matter physics and quantum-information methods. The immediate goals of our project are to understand quantitatively the subtle interplay of quantum phenomena in insulators and conductors, explore new promising directions for the engineering of transport in real materials, and lay the foundations for the design of the quantum materials of tomorrow.", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["FETPROACT-3-2014 - Quantum simulation"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2015-03-01"], "Project_ID": ["641122"], "Call_for_Proposal": ["H2020-FETPROACT-2014"]}, -{"Partners": ["NOVA ID FCT - ASSOCIACAO PARA A INOVACAO E DESENVOLVIMENTO DA FCT", "LABORATORIO NACIONAL DE ENGENHARIA CIVIL", "ECOLE NATIONALE SUPERIEURE DES MINES D'ALES", "INSTITUT MINES-TELECOM", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "INSTITUTO DE SOLDADURA E QUALIDADE", "AR DIAGNOSTIC TECNOLOGIAS DE MONITORIZACAO E CONTROLO DO AR LDA", "TECHNOLOGIES EXPERTISES RECHERCHES ANALYTIQUES EN ENVIRONNEMENT", "AMBISALUD CALIDAD AMBIENTAL SL", "ORRION CHEMICALS METALCHEM", "DONETSK INSTITUTE FOR PHYSICS AND ENGINEERING NAMED AFTER O.O. GALKIN OF THE NATIONAL ACADEMY OF SCIENCESS OF UKRAINE", "MATERIALS RESEARCH CENTER", "NANOTECHCENTER LLC", "UNIVERSITE PARIS-SUD", "BELARUSIAN STATE UNIVERSITY"], "EU_Contribution": ["EUR 1 386 000"], "Project_Title": ["NANOMATERIALS-BASED INNOVATIVE ENGINEERING SOLUTION TO ENSURE SUSTAINABLE SAFEGUARD TO INDOOR AIR"], "Total_Cost": ["EUR 1 386 000"], "Country": ["Portugal", "Portugal", "France", "France", "France", "Portugal", "Portugal", "France", "Spain", "France", "Ukraine", "Ukraine", "Ukraine", "France", "Belarus"], "Project_ACR": ["NANOGUARD2AR"], "Technology_Description": "The overall project idea is on contribution to European culture and creativity through developing technological readiness of the breakthrough engineering solution for indoor air safeguard via inter-sectoral European and international cooperation, knowledge sharing, broad skills development and mobility of researchers and innovation staff. ", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Portugal"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["690968"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["POLITECNICO DI MILANO", "ECOLE CENTRALE DES ARTS ET MANUFACTURES", "UNIVERSITE LIBRE DE BRUXELLES", "TECHNISCHE UNIVERSITAT DARMSTADT"], "EU_Contribution": ["EUR 3 832 293,60"], "Project_Title": ["Combustion for Low Emission Applications of Natural Gas"], "Total_Cost": ["EUR 3 832 293,60"], "Country": ["Italy", "France", "Belgium", "Germany"], "Project_ACR": ["CLEAN-Gas"], "Technology_Description": "Natural Gas (NG) will be one of the key parameters of the EU energy policy for the next decades. EU gas imports are expected to reach over 80% of total consumption by 2030. Thus, the EU is investing heavily in natural gas equipment. ", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-EJD - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-EJD)"], "Funding_scheme": ["MSCA-ITN-EJD - European Joint Doctorates"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-01-01"], "Project_ID": ["643134"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI TRENTO"], "EU_Contribution": ["EUR 180 277,20"], "Project_Title": ["RNA-mediated intercellular miscommunication: role of extracellular vesicle cargos in Amyotrophic Lateral Sclerosis"], "Total_Cost": ["EUR 180 277,20"], "Country": ["Italy"], "Project_ACR": ["ExItALS"], "Technology_Description": "Amyotrophic Lateral Sclerosis (ALS) is a rare neurodegenerative disorder that primarily targets upper and lower motor neurons. The progression of the disease is mediated by altered intercellular communication in the spinal cord between neurons and glial cells. Intercellular communication, mainly happening through extracellular vesicles (EVs) is responsible for the horizontal transfer of proteins and RNAs to recipient cells. Recently, I proved that EVs released from ALS mutant astrocytes selectively induced toxicity in wild type motor neuron, thus reinforcing the notion that astrocytes exert toxicity in ALS disease propagation and suggesting EVs as mediators of toxicity. Although, multiple factors can play a role in motor neuron degeneration, recent evidences point toward a fundamental role for RNA and RNA-binding protein dys-homeostasis as crucial players in ALS pathogenesis. Therefore, the overarching goal of ExItALS is to characterize the astrocyte-EVs RNA cargos, -through RNA deep-sequencing (Aim1). This approach will be complemented by the use of high-resolution flow cytometry (secondment) to separate EV populations and determine which one(s) is(are) responsible for motor neuron toxicity (Aim2). The present research proposal is a synthesis of my interests in neurodegenerative diseases and my expertise in biochemistry and neurobiology. At the Host Institution I will greatly benefit from the scientific exchange with several PIs interested in RNA biology, particularly with my supervisor, whose skills in RNA-binding protein biology and bioinformatics analyses will perfectly integrate and consolidate my molecular and biochemical expertise. The MSCA-RI-IF will be instrumental to develop this initial hypothesis into deeper biological understanding of ALS and represent a crucial support to my scientific integration as a competitive, woman investigator in the transition from a researcher position to an independent academic career.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["752470"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI TRENTO"], "EU_Contribution": ["EUR 180 277,20"], "Project_Title": ["A novel in vivo platform to study and target undruggable Ewing onco-chimera."], "Total_Cost": ["EUR 180 277,20"], "Country": ["Italy"], "Project_ACR": ["EwiSarc"], "Technology_Description": "Development of efficient therapeutic strategies in the past years has drastically reduced the lethality of several common types of pediatric and juvenile form of cancer such as leukemia, lymphoma and brain tumors. Such a tremendous success, however, does not include sarcomas treatment, whose mortality rate remains the same as twenty years ago. ", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["749795"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF LEEDS"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Antiferromagnetic straintronics: towards an non-volatile all-voltage controlled memory device"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["PiezoSpin"], "Technology_Description": "The holy grail of magnetic storage research is the discovery of novel all-voltage controlled magnetic metamaterials that enable to develop a universal memory device that simultaneously meet high-power-efficiency and ultra-high storage capacity. Antiferromagnetic (AFM) materials could represent the future of spintronic applications as a result of the numerous interesting features they combine, e.g. they are robust against perturbation due to magnetic fields, produce no stray fields, display ultrafast dynamics and are capable of generating large magneto-transport effects. However, the truly distinctive feature posed by AFM materials when compared to ferromagnetic ones is its modulated magnetic order, which is marginally exploited in spintronics applications.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["748691"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI TORINO", "POLITECNICO DI TORINO", "UNIVERSITA DEGLI STUDI DEL PIEMONTE ORIENTALE AMEDEO AVOGADRO", "UNIVERSITA DEGLI STUDI DI SCIENZE GASTRONOMICHE", "CENTROSCIENZA ONLUS ASSOCIAZIONE", "CREATIVA IMPRESA DI COMUNICAZIONE SRL"], "EU_Contribution": ["EUR 184 250"], "Project_Title": ["Tenth Researchers' night Anniversary for Citizenship in the Knowledge Society"], "Total_Cost": ["EUR 279 250"], "Country": ["Italy", "Italy", "Italy", "Italy", "Italy", "Italy"], "Project_ACR": ["TRACKS"], "Technology_Description": "The Researchers\u2019 Night has been for the eight past editions a regular appointment for researchers and for the different publics of science in Piedmont.", "To": ["2015-11-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-NIGHT-2014 - European Researchers' Night (NIGHT)"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2014-04-01"], "Project_ID": ["633275"], "Call_for_Proposal": ["H2020-MSCA-NIGHT-2014"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI TRENTO", "META GROUP SRL"], "EU_Contribution": ["EUR 99 750"], "Project_Title": ["WhiteRabbit: easily revealing and managing personal information."], "Total_Cost": ["EUR 99 750"], "Country": ["Italy", "Italy"], "Project_ACR": ["WhiteRabbit"], "Technology_Description": "WhiteRabbit aims to bring to the market an innovative software platform. The platform will allow to extract value from personal data, while keeping its subjects in the loop and also complying with upcoming regulations.", "To": ["2018-07-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-04-2016-2017 - FET Innovation Launchpad"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-04-01"], "Project_ID": ["754436"], "Call_for_Proposal": ["H2020-FETOPEN-4-2016-2017"]}, -{"Partners": ["INSTITUT MINES-TELECOM", "INSTITUT MINES-TELECOM"], "EU_Contribution": ["EUR 1 495 287,52"], "Project_Title": ["Context- and Task-Oriented Communication"], "Total_Cost": ["EUR 1 495 287,52"], "Country": ["France", "France"], "Project_ACR": ["CTO Com"], "Technology_Description": "Emergence of a large number of distributed decision and control systems (e.g., in health care, transportation, and energy management), combined with increasing demands of traditional communications (e.g., due to multiview videos), create an imminent need for highly improved communication systems. We advocate that\u2014combined with improvements in battery, antenna, and chip technologies\u2014context- and/or task-oriented communication techniques will bring the desired breakthrough. Specifically, context- oriented techniques will greatly improve performance, because future networks have complex infrastructures (with cache-memories, cloud-RANs, etc.) allowing the terminals to collect side-informations about other terminals\u2019 data or signals, and because many distributed decision systems rely on numerous devices with correlated measurements. Task-oriented techniques promise even larger gains, especially in distributed decision systems where decisions take value on a small range, and thus the traditional approach of communicating sequences of observed signals results in a huge overhead.", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["715111"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI TRENTO", "UNIVERSITA DEGLI STUDI DI TRENTO"], "EU_Contribution": ["EUR 1 499 482"], "Project_Title": ["Culture-free strain-level population genomics to identify disappearing human-associated microbes in the westernized world"], "Total_Cost": ["EUR 1 499 482"], "Country": ["Italy", "Italy"], "Project_ACR": ["MetaPG"], "Technology_Description": "Investigating symbiotic gut microbes with large-scale comparative genomics would allow gaining crucial insights into the \u201cepidemiology\u201d, genetic diversity, and population structure of hundreds of scarcely characterized microorganisms. However, cultivation-based approaches are ineffective at targeting the large fraction of the gut microbial diversity that is hard be grown in vitro. They are also expensive and time consuming, as they need sampling specific bacteria from geographically separated subjects. On the other hand, cultivation-free metagenomic data is now available for thousands of stool samples collected worldwide, but they are not currently exploited for strain-level microbial population genomics because of the lack of suitable computational methods. In Aim1, we leverage our expertise in computational biology to bridge the gap between the fields of metagenomics and population genomics by developing novel and highly innovative methodologies to extract strain-level genomic and genetic profiles from metagenomic samples with the resolution needed by comparative genomics. Such paradigmatic shift will put us in the position of reusing in Aim2 the thousands of available metagenomes and unravel for the first time the population structure of hundreds of uncultivable gut microbes. Among the novel tasks enabled, we will focus in Aim3 on identifying those microbial strains that are currently disappearing in westernized populations as a consequence of urbanization, industrialization, high-fat diets. We will complement the available data with gut metagenomes from novel targeted cohorts of both westernized and non-westernized populations. Our project defines the foundation for cultivation-free strain-level population genomics, provides comparative genomics results with unprecedented resolution for hundreds of under-investigated microbes, and compiles a catalogue of strains undergoing or at risk of primary, secondary, or ecological extinction in westernized populations.", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["716575"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI TRENTO"], "EU_Contribution": ["EUR 180 277,20"], "Project_Title": ["Quantifying ecological effects of small hydropower in Alpine stream ecosystems"], "Total_Cost": ["EUR 180 277,20"], "Country": ["Italy"], "Project_ACR": ["SHYDRO-ALP"], "Technology_Description": "In Europe, hydropower is the largest renewable energy resource accounting for 16% of total production, most of which is concentrated in the Alpine region. However, this renewable energy comes at great environmental costs and development of large dams is now considered untenable in many Countries. While studies addressing the ecological implications of hydropower have mostly focused on large facilities, investigations on small hydropower (SHP) are scarcer. Yet, development of SHP is booming globally and in the Alps rising concerns about cumulative effects on riverine systems.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["748969"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["LUCIDEON LIMITED", "THE UNIVERSITY OF WESTMINSTER LBG", "POLITECNICO DI TORINO", "FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG", "VORNIA LIMITED", "UNIVERSITY OF SOUTHAMPTON", "UNIVERSITAETSKLINIKUM KNAPPSCHAFTSKRANKENHAUS BOCHUM GMBH"], "EU_Contribution": ["EUR 3 918 054,96"], "Project_Title": ["Drug-Free Antibacterial Hybrid Biopolymers for Medical Applications"], "Total_Cost": ["EUR 3 918 054,96"], "Country": ["United Kingdom", "United Kingdom", "Italy", "Germany", "Ireland", "United Kingdom", "Germany"], "Project_ACR": ["HyMedPoly"], "Technology_Description": "There is a general consensus that biomedical polymers of natural and synthetic origin should and will play a very important role in the development of new therapeutic strategies to treat diseases. Due to resistance of bacteria to drugs, infection has become one of the toughest problems in the medical world as there are hardly any effective antibiotics left in the fight against many pathogens. This project aims to develop new therapies through a new combination of technology (a) development of new hybrid polymers with antibacterial functionality,(b) introduction of inhibitors that can permanently deactivate bacteriological proteases and (c) new formulations of bioactive ceramics and glasses that have specific charge potential to prevent bacterial growth. The challenge is to develop new medical polymers that have an intrinsic antibacterial functionality to achieve clinical effectiveness in the field. To develop the challenge to practical medical solutions, a new generation of industrial professionals is needed. They should have a solid multidisciplinary background complemented by the required academic and industrial experiences. The objective of this network is to train young PhD researchers to fill this demand in the strategic area of drug-free antibacterial hybrid biomedical polymers. This EID programme will achieve this by a joint training programme of world class academic and industrial institutes who will provide hands-on training in state of the art research projects related to key fundamental issues that determine the future new therapies of antibacterial biomaterials. The goal is to develop professionals that will play a pivotal role in pushing forward this challenging and knowledge-intense field for the coming decades to benefit the European economy, bring state-of-the-art technology to industry with advanced products for hospitals and personal health care and contribute to the development of therapeutic strategies to improve the quality of life.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-EID - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-EID)"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["United Kingdom"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["643050"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["UNIVERSITE D'ANGERS"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Gender and transnational Humanitarian Commitment for Children (Europe - 1980-2007)"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["GenHumChild"], "Technology_Description": "The main objective of this project is to examine the extent to which \u201cgender\u201d, as category of analysis, can be a useful tool in explaining the nature and the impact of humanitarian aid of western organizations towards children in Europe, between 1980 and 2007, using as case study the relation France (initiator)-Romania (beneficiary). The main objectives are: to identify all the stakeholders involved in the humanitarian aid for children, the targeted problems, if the large framework of intervention to see if formally it addressed these gender particularities; to describe the grassroots activity and the human resources of the humanitarian organisations involved in aiding the children, with a special focus on the motivation(s) that stood behind both the personal and institutional involvement and of there any differences between women and men; a survey on the local impact of each of the major intervention axes, insisting on sensitive issues, such as the accusations of paedophilia and the scandal surrounding international adoptions.", "To": ["2019-09-03, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-04"], "Project_ID": ["748770"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KING'S COLLEGE LONDON"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["A Nano-photoelectric Exosome Biosensor for Point-of-care Diagnosis of Early-stage Cancer"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ExoSensor"], "Technology_Description": "Tumour-derived circulating exosomes are an ideal, easily accessible reservoir of cancer biomarkers to assess disease processes. Quantitatively pinpointing exosome tumour markers, a clinical field of an unmet need is appealing, yet challenging. The main objectives of the proposal are to develop an integrated dual-signalling exosome biosensor (ExoSensor) for rapid and specific detection of GPC1+ exosomes and fabricate a 3D-printed portable prototype for POCT diagnosis of pancreatic cancer, offering an universal technology for clinical cancer diagnosis through quantitatively monitoring the protein marker of cancer-derived exosomes, in a simple way. The novelty resides in creatively achieving accurate, sensitive, and simultaneous detection of exosomes by integrating two synergetic methods (optical and electrochemical) on one single nanosensing platform, avoiding false positive/negative results to the utmost and ensuring the reliability of tests. This European Fellowship at Kings College London will provide the researcher with advanced technical training in molecular biology, exosome, cancer cell and animal handling, analytical chemistry and microscopy and imaging techniques, as well as academic mentoring in research management. A secondment to Cardiff University will seek and confirm the best possible biomarker(s). Another secondment to the industrial partner AstraZeneca Ltd will offer access to various exosomes research (diagnostics, toxicology and therapeutics) and evaluate the feasibility of commercial transfer if possible. Guy\u2019s, St Thomas, and King\u2019s College Hospital (part of King\u2019s Health Partners) will provide valuable clinical samples for final validation stage. Other collaborators will advise on 3D-printing, pancreatic cancer and biomarkers. These interdisplinary contributions are essential and well-related to the proposal research, fostering high-quality cooperation from biology, chemistry, engineering, nanotechnology and clinical areas the other way round.", "To": ["2019-10-10, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-11"], "Project_ID": ["749087"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA", "UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["e-Sequence: a sequential approach to engineer heteroatom doped graphene nanoribbons for electronic applications"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Spain", "Spain"], "Project_ACR": ["e-Sequence"], "Technology_Description": "Graphene nanoribbons (NR) are quasi-1D nanostructures with discrete band gaps, ballistic conduction, and one-atom thickness. Such properties make them ideal candidates to develop low-dimensional semiconductors, which are essential components in nanoelectronics. Atomically-precise control over the structure of NR (width, length, edge, doping) is crucial to fully exploit their potential. However, current approaches for the synthesis of NR suffer from several drawbacks that do not allow attaining such level of precision, therefore alternative methods need to be sought.", "To": ["2022-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["722951"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["SERVICIO DE SALUD DE CASTILLA LA MANCHA", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "AXON CABLE", "UNIVERSITA DEGLI STUDI DI TRENTO", "KUNGLIGA TEKNISKA HOEGSKOLAN", "UNIVERSITE D'AIX MARSEILLE", "UNIVERSITAT DES SAARLANDES"], "EU_Contribution": ["EUR 5 094 120"], "Project_Title": ["Biofunctionalised Electroconducting Microfibres for the Treatment of Spinal Cord Injury"], "Total_Cost": ["EUR 5 888 491,25"], "Country": ["Spain", "United Kingdom", "France", "Italy", "Sweden", "France", "Germany"], "Project_ACR": ["Neurofibres"], "Technology_Description": "Bio-electronic microsystems hold promise for repairing the damaged central nervous system (CNS). However, this potential has not been developed because their implantation inflicts additional neural injury, and ensuing inflammation and fibrosis compromise device functionality. In Neurofibres we want to achieve a breakthrough in \u201cNeuroregenerative Bio-electronics\u201d, developing dual-function devices that will serve as electroactive scaffolds for CNS regeneration and neural circuit activation. We engineered electroconducting microfibres (MFs) that add negligible tissue insult while promoting guided cell migration and axonal regeneration in rodents with spinal cord injury (SCI). The MFs also meet the challenge of probe miniaturisation and biofunctionalisation for ultrasensitive recording and stimulation of neural activity. An interdisciplinary consortium composed of neuroscientists, medical specialists, researchers in biomaterials, protein engineering, physics, and electrical and mechanical engineering, together with a company specialised in fabrication of microcables and microconnectors, will join efforts to design, develop, and test the MFs and complementary technology (microfibre functionalisation, assembling, and electronic interconnection), in order to produce a biologically safe and effective bio-electronic system for the treatment of SCI. This goal will be achieved through five specific objectives: ", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["FETPROACT-01-2016 - FET Proactive: emerging themes and communities"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Spain"], "Activity": ["Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Corinna Hahn", "Tel.: +49 681 95 92 3362", "Fax: +49 681 95 92 3370"], "From": ["2017-01-01"], "Project_ID": ["732344"], "Call_for_Proposal": ["FETPROACT-2016"]}, -{"Partners": ["GREGOR-MENDEL-INSTITUT F\u00dcR MOLEKULARE PFLANZENBIOLOGIE GMBH", "GREGOR-MENDEL-INSTITUT F\u00dcR MOLEKULARE PFLANZENBIOLOGIE GMBH"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Function and Evolution of Attack and Response Strategies during Allelopathy in Plants"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Austria", "Austria"], "Project_ACR": ["FEAR-SAP"], "Technology_Description": "In natural and agricultural habitats, plants grow in organismal communities and therefore have to compete for limited resources. Competition between different crop plants and between crops and weeds leads to losses of potential agricultural product and requires heavy use of fertilizer and herbicides, with negative effects for the environment and human health. Plants have evolved various strategies to outcompete their neighbours and to secure their access to resources; one of them is the release of toxic chemical compounds into the soil that interfere with the growth of neighbouring plants. Many of today\u2019s major crops, such as wheat, rye and maize, produce phytotoxins. Conversely, crop species also suffer from chemical attack by other plants growing in their vicinity. Although many of the chemical compounds applied in this biochemical warfare have been identified, we know little about how they act in the target plant; neither do we understand how some plant species are able to tolerate this chemical attack.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Austria"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["716823"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["RIJKSUNIVERSITEIT GRONINGEN", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "TECHNISCHE UNIVERSITAET CHEMNITZ", "BAYERISCHE JULIUS-MAXIMILIANS UNIVERSITAT WURZBURG", "UNIVERSITE DE MONS", "TECHNISCHE UNIVERSITAET DRESDEN", "HELIATEK GMBH", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "UNIVERSITE D'ANGERS", "MERCK CHEMICALS LTD", "FUNDACIO EURECAT"], "EU_Contribution": ["EUR 3 826 023,84"], "Project_Title": ["Spins for Efficient Photovoltaic Devices based on Organic Molecules"], "Total_Cost": ["EUR 3 826 023,84"], "Country": ["Netherlands", "United Kingdom", "Germany", "Germany", "Belgium", "Germany", "Germany", "Spain", "France", "United Kingdom", "Spain"], "Project_ACR": ["SEPOMO"], "Technology_Description": "Organic solar cells (OSCs) have the potential to become an environmental friendly, inexpensive, large area and flexible photovoltaics technology. Their main advantages are low process temperatures, the potential for very low cost due to abundant materials and scalable processing, and the possibility of producing flexible devices on plastic substrates. To improve their commercialization capacity, to compete with established power generation and to complement other renewable energy technologies, the performance of state-of-the-art OSCs needs to be further improved.", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations"], "From": ["2016-11-01"], "Project_ID": ["722651"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["POLITECNICO DI MILANO", "TECHNISCHE UNIVERSITAET BERLIN", "FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA", "STICHTING VU"], "EU_Contribution": ["EUR 742 500"], "Project_Title": ["Localized Surface Plasmon Resonance in doped semiconductor nanocrystals"], "Total_Cost": ["EUR 1 107 000"], "Country": ["Italy", "Germany", "Italy", "Netherlands"], "Project_ACR": ["SONAR"], "Technology_Description": "Doped semiconductor nanocrystals (dSNCs) are an exciting emerging material. Carrier densities in the range of 1020-1021cm-3 lead to localized surface plasmon resonances (LSPRs) in the near infrared (NIR). Prominent examples are copper chalcogenides, where doping occurs via vacancy formation, and metal oxides (MOs) that show plasmonic response due to impurity doping. Excitingly, both materials display post synthetic carrier density and LSPR tunability over a broad spectral range. Combined with layered two dimensional materials exciting manipulation options appear where the plasmon-exciton coupling or \u2018hot\u2019 carrier extraction enables local photo luminescence manipulation or tracking of local currents in a graphene based nano device. This active control over the LSPR allows active switching of the strength of coupling, useful also for the study of exciton-plasmon, plasmon-plasmon coupling, or plasmon induced \u2018hot\u2019 carrier extraction in nano-heterostructures. Ultralow doping allows the study of quantum plasmonics. Ultrafast photodoping, optical switching, active light manipulation or tunable NIR photon detection are additional exciting applications. While fundamental questions regarding the structure-properties relationship remain open to date the library of materials with such properties is enormous and not yet exhausted. ", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Chiara Andreoli", "Tel.: +3901071781854", "Fax: +39 010 7170817", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["734690"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["CITY UNIVERSITY OF LONDON", "CITY UNIVERSITY OF LONDON"], "EU_Contribution": ["EUR 1 499 672"], "Project_Title": ["Revealing the neurocognitive mechanisms underlying the visual perception of social interactions"], "Total_Cost": ["EUR 1 499 672"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["POINTS"], "Technology_Description": "\u201cSocial perception\u201d has emerged as an umbrella term to describe research addressing the visual perception of others. To date, this discipline has focused on the perception of individuals; for example, researchers have examined the visual processing of faces and facial expressions, body shapes and postures, actions and kinematics. The resulting body of research suggests that social stimuli are detected by specialised mechanisms, recruit dedicated perceptual models, and are processed by particular neural substrates. However, while social perception research has made considerable progress elucidating the visual perception of individuals, virtually nothing is known about the visual perception of social interactions; how we detect, encode, and interpret visual displays of social interactions viewed from third-person perspectives. Given the adaptive value of accurate interaction interpretation, this paucity of knowledge represents a remarkable gap in our understanding of social perception. POINTS will develop a battery of original behavioural and neuroimaging paradigms to reveal the neurocognitive mechanisms that mediate this essential form of social perception. The overarching objective of POINTS will be achieved by addressing five research questions: 1) Do observers exhibit evidence of interaction detection mechanisms? 2) How do we process fleeting visual displays of social interactions? 3) How do we represent dynamic interaction change? 4) Do specialised neural substrates mediate interaction perception? 5) Do some observers exhibit impaired interaction perception? The POINTS project represents a significant step-change in social perception research. Understanding the mechanisms of interaction perception will provide new insights into the organisation of the human visual system, and will inform attempts to remediate socio-cognitive and perceptual deficits in neurodevelopmental populations, including those with Autism Spectrum Disorder.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["715824"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["INSTITUT MINES-TELECOM"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Bioconductive Iongels for Cutaneous Electrophysiology"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["BIKE"], "Technology_Description": "Bioelectronics is limited by the materials that transducer signals across the interface between biology and electronics. For example, in cutaneous recording, the interface between the electrode and skin is the key parameter to get a good recording. For these applications, there is a great deal of interest in developing soft conducting coatings that decrease the impedance between the electrode and the skin. Hence, the interface between the skin and the electrode is improved allowing an easier flow of the ionic and electronic current. Although hydrogel based electrolytes are in use, the continuous evaporation of water does not allow the long-term cutaneous recording. The current proposal is aiming at exploring innovative materials such as iongels that can enhance the ionic conductivity and decrease the impedance with the human skin without suffering evaporation during the recording due to the negligible vapour pressure of ionic liquids. These cutaneous electrodes will be used to monitor the electrical activity of specific organs for a better understanding of the physiology and the pathology of different organs.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["742865"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["POLITECNICO DI TORINO", "OPTIFLOW", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 794 224,80"], "Project_Title": ["Sand Mitigation around Railway Tracks"], "Total_Cost": ["EUR 794 224,80"], "Country": ["Italy", "France", "United Kingdom"], "Project_ACR": ["SMaRT"], "Technology_Description": "In the last decade, a growing number of railways and other civil or industrial infrastructures have been designed and/or built in arid regions worldwide. The European Railway Industry is often selected for such projects, because of its strong overall know-how.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["721798"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["POLITECNICO DI MILANO", "TECHNISCHE UNIVERSITEIT DELFT", "THE UNIVERSITY OF LIVERPOOL", "UNIVERSITY OF GLASGOW"], "EU_Contribution": ["EUR 3 146 893,92"], "Project_Title": ["Network for Innovative Training on ROtorcraft Safety"], "Total_Cost": ["EUR 3 146 893,92"], "Country": ["Italy", "Netherlands", "United Kingdom", "United Kingdom"], "Project_ACR": ["NITROS"], "Technology_Description": "Helicopters and the other vertical flight vehicles, like tilt-rotors, compound helicopters, hybrids and rapidly expanding class of easy to fly vertical take-off personal vehicles, are expected to see widespread use in the future especially as means of transport, exploiting the formidable capability to provide point-to-point connections.", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EJD - European Joint Doctorates"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-11-01"], "Project_ID": ["721920"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["THE QUEEN'S UNIVERSITY OF BELFAST", "DEUTSCHES ZENTRUM FUER LUFT - UND RAUMFAHRT EV", "PANEPISTIMIO PATRON", "UNIVERSITY OF ULSTER", "SWEREA SICOMP AB", "SHORT BROTHERS PLC", "CENTRO RICERCHE FIAT SCPA", "UNIVERSITY OF LIMERICK", "POLITECNICO DI TORINO"], "EU_Contribution": ["EUR 3 933 281,52"], "Project_Title": ["Improving the crashworthiness of composite transportation structures"], "Total_Cost": ["EUR 3 933 281,52"], "Country": ["United Kingdom", "Germany", "Greece", "United Kingdom", "Sweden", "United Kingdom", "Italy", "Ireland", "Italy"], "Project_ACR": ["ICONIC"], "Technology_Description": "The European aerospace, automotive, and rail industries are committed to improving their energy efficiency to meet targets set within the EU\u2019s climate, energy and transport policies. This is motivating the increased use of lightweight composite materials in lieu of heavier metallics. To implement this transition, these industries must reach, at least, the same level of crash performance achieved with metals, but at significantly lower weight and without increasing cost. This is viewed by industry as an exceptionally challenging goal and will require highly trained engineers, versed in the myriad aspects of designing cost-effective, crashworthy composites structures, and capable of harnessing the latest research developments in the fast-changing world of composites. The ICONIC ETN aims to cultivate such a new generation of young engineers; comfortable and fluent in the integration and exploitation of knowledge from fields as diverse as materials science, chemistry, computational methods, solid and damage mechanics, textile technology, structural design and optimisation. These researchers will acquire the skills to enable the sustainable and economically-viable design of a new generation of highly efficient, lightweight transportation composite structures that will provide the maximum protection to occupants through superior crashworthiness. 15 Early Stage Researchers (ESRs) will be recruited to take up posts, across the UK, Ireland, Greece, Germany, Italy and Sweden, in an innovative, multidisciplinary and intersectoral structured research and training programme. ICONIC is supported by a strong consortium from academia, large industrial enterprises and innovative SMEs. A comprehensive training and secondment programme (including joint supervision and industrial mentoring) will equip researchers with additional transferable skills to ensure future employability and career progression.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["721256"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["POLITECNICO DI TORINO", "POLITECNICO DI TORINO"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Integrated Smart Device for Emergency Management"], "Total_Cost": ["EUR 150 000"], "Country": ["Italy", "Italy"], "Project_ACR": ["IDEAL SENSOR"], "Technology_Description": "The project IDEAL SENSOR is developing a wearable wrist band device and a customized structural health monitoring (SHM) system for managing emergencies. The proposed system provides a comprehensive solution for indoor localization, healthcare monitoring, and other general purpose services (fitness, entertainment, health, etc.). Moreover, an infrastructure based on the structural health monitoring will be developed which include all the functionality of standard Structural Health Monitoring (SHM) systems (environmental monitoring, health assessment, etc.), but it performs also indoor localization. In detail, the system is composed of different environmental monitoring sensors (humidity and temperature), body signal monitoring (heart rate, body temperature, humidity, location and images), communication modules (radio frequency (RF) transceiver, GPRS/GSM, GPS and Bluetooth low energy), OLED display. Currently , the prototype has been developed and tested in a STM Nucleo-F401 board which is a developing board provided by STMicroelectronics commonly used for rapid prototyping. In order to commercialize the prototype and make it a feasible product, the current developed system should be redesigned and customized based on our needs and requirements. The electrical parts will be redesigned completely and the best available solutions (price and quality) for each sub-module and components will be used. Moreover, by miniaturizing the prototype and designing a user friendly package and software, it will get the shape of a real smart watch with more features with respect to the current ones.", "To": ["2018-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["727261"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Crosstalk between microbiota metabolites and immune cells, the missing link to brain damage."], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["MetaBiota"], "Technology_Description": "Stroke is the second most common cause of death in Europe: accounting for almost 1.1 million deaths each year, with only 15% of stroke patients being eligible for a specific treatment. I have reported\u2013in this year Nature Medicine\u2019s April issue\u2013that microbiota influences the severity of stroke injury through an impaired intestinal immune function. These findings revealed for the first time the critical implication of the microbiota as a novel and relevant prospective target for therapeutic strategies in stroke. However, the development of efficient therapies requires to identify which bacterial species and bacterial products are involved in the modulation of the immune response and thereby influence stroke outcome. ", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["753893"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ARISTOTELIO PANEPISTIMIO THESSALONIKIS", "AGRITEST SRL", "BETA FIDAN DOKU KULTURU ISLAH ARGEZIRAAT TARIM SULAMA HAYVANCILIK GIDA TURIZM INSAAT SANAYI TICARET LIMITED SIRKETI", "BIOREBA AG", "CONSIGLIO NAZIONALE DELLE RICERCHE", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "XILOGIANNIS BROSS UN.CO", "FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS", "LIFESEQUENCING SL", "MUSTAFA KEMAL UNIVERSITY", "NAMIK KEMAL UNIVERSITESI*NAMIK KEMAL UNIVERSITY NKU", "INSTITUTO VALENCIANO DE INVESTIGACIONES AGRARIAS", "UNIVERSITA DEGLI STUDI DELLA BASILICATA", "INSTITUTE OF PLANT PROTECTION CHINESE ACADEMY OF AGRICULTURE SCIENCES", "INSTITUTO SUPERIOR POLITECNICO DO KWANZA SUL", "UNIVERSITY OF PRETORIA"], "EU_Contribution": ["EUR 630 000"], "Project_Title": ["Virus free Fruit Nurseries"], "Total_Cost": ["EUR 787 500"], "Country": ["Greece", "Italy", "Turkey", "Switzerland", "Italy", "France", "Greece", "Greece", "Spain", "Turkey", "Turkey", "Spain", "Italy", "China", "Angola", "South Africa"], "Project_ACR": ["VirFree"], "Technology_Description": "Fruit trees and grapevine are propagated vegetatively and are often grafted. As a result they suffer from a high number of pathogens such as viruses and viroids, a number of which are causing severe yield losses and reduce the productive life of the affected plants. As these pathogens cannot be controlled by the application of chemicals, the most efficient way to combat them is the production and commercialization of high quality pathogen-tested propagative material. Nevertheless, this procedure is not simple and both academia and private sectors are working towards its improvement. In this direction was built the herein interdisciplinary proposal which brings together academia and private companies to collaborate through their expertise on the following objectives: 1) to identify new viral and viroid strains or species affecting fruit trees and grapevine, 2) to optimise existing and develop novel detection methods and 3) to improve propagation and sanitation methods for producing high quality (virus-tested) plant material of fruit trees and grapevine. In this project diagnostic tools that are currently used in certification programs will be combined with cutting edge technologies such as NGS and Nanobodies. The project has eight academic partners within the EU and associated countries, three within Third Countries and five non-academic partners. The knowledge obtained will be shared among the partners of the proposal and further disseminated to academic institutions, nurseries and other private sectors. Most importantly training of a new generation of researchers will be done in close contact to the needs of both industrial and academic sectors. In conclusion, the results of this proposal will enrich the knowledge on viruses/viroids associated with different diseases, improve the sensitivity of their detection methods, lead to new detection products and further contribute to the improvement of the disseminated propagative material of fruit trees and grapevine.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Greece"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["734736"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["POLITECNICO DI TORINO", "POLITECNICO DI TORINO", "INSTITUT MINES-TELECOM"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["from Cubic To Linear complexity in computational electromagnetics"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Italy", "Italy", "France"], "Project_ACR": ["321"], "Technology_Description": "Computational Electromagnetics (CEM) is the scientific field at the origin of all new modeling and simulation tools required by the constantly arising design challenges of emerging and future technologies in applied electromagnetics. As in many other technological fields, however, the trend in all emerging technologies in electromagnetic engineering is going towards miniaturized, higher density and multi-scale scenarios. Computationally speaking this translates in the steep increase of the number of degrees of freedom. Given that the design cost (the cost of a multi-right-hand side problem dominated by matrix inversion) can scale as badly as cubically with these degrees of freedom, this fact, as pointed out by many, will sensibly compromise the practical impact of CEM on future and emerging technologies. ", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["724846"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["POLITECNICO DI TORINO"], "EU_Contribution": ["EUR 180 277,20"], "Project_Title": ["Flexible Optical Networks \u2013 Time Domain Hybrid QAM: DSP and Physical Layer Modelling"], "Total_Cost": ["EUR 180 277,20"], "Country": ["Italy"], "Project_ACR": ["Flex-ON"], "Technology_Description": "The delivery of fast Internet connections all over Europe is a primary goal of Horizon 2020. In order to avoid the upcoming capacity crunch on transport optical networks, there is an urgent need for a strong investment in the research and development of future-proof optical broadband infrastructures. The Flex-ON project will investigate new technological paradigms in terms of signal generation, digital processing and control-plane management for novel flexible and high-capacity transport optical networks. The primary technical objective of the project is to develop and implement a flexible transceiver prototype with intelligent reconfigurability and arbitrarily low bit-rate granularity. The development of this technology will enable to increase the network capacity and the spectral/energy efficiency, while providing a future-proof flexible solution for an increasingly heterogeneous global network.", "To": ["2017-10-15, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-10-16"], "Project_ID": ["653412"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["POLITECNICO DI TORINO", "POLITECNICO DI TORINO"], "EU_Contribution": ["EUR 1 977 500"], "Project_Title": ["Biomimetic trick to re-balance Osteblast-Osteoclast loop in osteoporoSis treatment: a Topological and materials driven approach"], "Total_Cost": ["EUR 1 977 500"], "Country": ["Italy", "Italy"], "Project_ACR": ["BOOST"], "Technology_Description": "One out of 5 people in their fifties will experience a bone fracture due to osteoporosis (OP)-induced fragility in their lifetime. The OP socio-economic burden is dramatic and involves tens of millions of people in the EU, with a steadily increasing number due to population ageing. Current treatments entail drug-therapy coupled with a healthy lifestyle but OP fractures need mechanical fixation to rapidly achieve union: the contribution of biomaterial scientists in this field is still far from taking its expected leading role in cutting-edge research. Bone remodelling is a well-coordinated process of bone resorption by osteoclasts followed by the production of new bone by osteoblasts. This process occurs continuously throughout life in a coupling with a positive balance during growth and negative with ageing, which can result in OP. We believe that an architecture driven stimulation of the osteoclast/osteoblast coupling, with an avant-garde focus on osteoclasts activity, is the key to success in treating unbalanced bone remodelling. We aim to manufacture a scaffold that mimics healthy bone features which will establish a new microenvironment favoring a properly stimulated and active population of osteoclasts and osteoblasts, i.e. a well-balanced bone cooperation. After 5 years we will be able to prove the efficacy of this approach. A benchmark will be set up for OP fracture treatment and for the realization of smart bone substitutes that will be able to locally \u201ctrick\u201d aged bone cells stimulating them to act as healthy ones. BOOST results will have an unprecedented impact on the scientific research community, opening a new approach to set up smart, biomimetic strategies to treat aged, unbalanced bone tissues and to reduce OP-associated disabilities and financial burdens.", "To": ["2021-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["681798"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["POLITECNICO DI TORINO", "POLITECNICO DI TORINO"], "EU_Contribution": ["EUR 1 222 500"], "Project_Title": ["Coping with water scarcity in a globalized world"], "Total_Cost": ["EUR 1 222 500"], "Country": ["Italy", "Italy"], "Project_ACR": ["CWASI"], "Technology_Description": "We intend to set up a new globalized perspective to tackle water and food security in the 21st century. This issue is intrinsically global as the international trade of massive amounts of food makes societies less reliant on locally available water, and entails large-scale transfers of virtual water (defined as the water needed to produce a given amount of a food commodity). The network of virtual water trade connects a large portion of the global population, with 2800 km3 of virtual water moved around the globe in a year. We provide here definitive indications on the effects of the globalization of (virtual) water on the vulnerability to a water crisis of the global water system. More specifically, we formulate the following research hypotheses: ", "To": ["2020-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-07-01"], "Project_ID": ["647473"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["POLITECNICO DI TORINO", "POLITECNICO DI TORINO"], "EU_Contribution": ["EUR 1 489 219"], "Project_Title": ["Hybrid immune-eluding nanocrystals as smart and active theranostic weapons against cancer"], "Total_Cost": ["EUR 1 489 219"], "Country": ["Italy", "Italy"], "Project_ACR": ["TROJANANOHORSE"], "Technology_Description": "Nanomedicine tools for cancer treatment comprise many nanosized systems, so far developed with smart functions such as efficient drug delivery and cell targeting abilities. However they remain still undercharacterized in terms of immunogenicity, potential toxicity due to the materials itself or the unwanted release of drugs. To overcome these challenges this project aims to develop a new generation of multifunctional therapeutic and diagnostic (thus theranostics) nanosystems displaying non-immunogenicity, improved cancer treatment, cell imaging, and high safety for the hosting organism. The innovative concept behind this approach relies on a core-shell nanosystem with a therapeutically active core, i.e. a TrojaNanoHorse (TNH), here validated against leukaemia. The injectable TNH have a lipid bilayer shell derived from autologous cancer cell membrane, naturally non-immunogenic. The hemocompatibility, antithrombogenicity, and targeting ability with antibodies toward malignant blood cells will be proved during this project. Studies will show the zinc oxide nanocrystal core activation developing toxic reactive oxygen species (ROS) for cancer killing, and its green fluorescence emission. The whole TNH would go beyond the state-of-the-art due to its nature-derived biomimetic shell, absence of drugs, its safety and biodegrading fate, and green luminescent emissions for diagnosis. This project will also develop novel set-up for non-immunogenic therapy and diagnosis, impacting on future technology, new standardized protocols for nanomaterial safety assessment, and study chemical and biological mechanism of ROS development effects on cancer cell. Achieving the ultimate goal of a multifunctional TNH will require multidisciplinary expertise in chemistry, material science, biology, medicine and engineering, opening new horizons as nanomedicine tools for efficient cancer therapy with strong scientific, technological and socio-economic benefits.", "To": ["2021-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["678151"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["POLITECNICO DI TORINO"], "EU_Contribution": ["EUR 197 720,10"], "Project_Title": ["ECOsystem services for resilient and sustainable cities: an ecohydrological approach for Green Urban Spaces"], "Total_Cost": ["EUR 197 720,10"], "Country": ["Italy"], "Project_ACR": ["ECO.G.U.S."], "Technology_Description": "For the first time in recorded history the majority of people live in cities and the increasing urbanization modifies their mass, momentum, and energy budgets: in the next decades redevelopment, densification, population increase and demographic shift, as well as climate change will potentially impact the production and consumption of urban ecosystem services. ", "To": ["2018-11-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-08-15"], "Project_ID": ["701914"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["POLITECNICO DI TORINO", "POLITECNICO DI TORINO"], "EU_Contribution": ["EUR 1 271 138"], "Project_Title": ["Integrated DEsign and control of Sustainable CommUnities during Emergencies"], "Total_Cost": ["EUR 1 271 138"], "Country": ["Italy", "Italy"], "Project_ACR": ["IDEal reSCUE"], "Technology_Description": "Integrated DEsign and control of Sustainable CommUnities during Emergencies", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-11-01"], "Project_ID": ["637842"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["POLITECNICO DI TORINO", "POLITECNICO DI TORINO"], "EU_Contribution": ["EUR 1 404 132"], "Project_Title": ["Design, manufacturing and control of INterfaces in THERMally conductive polymer nanocomposites"], "Total_Cost": ["EUR 1 404 132"], "Country": ["Italy", "Italy"], "Project_ACR": ["INTHERM"], "Technology_Description": "This proposal addresses the design, manufacturing and control of interfaces in thermally conductive polymer/graphene nanocomposites. ", "To": ["2020-02-29, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-03-01"], "Project_ID": ["639495"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["POLITECNICO DI TORINO"], "EU_Contribution": ["EUR 247 728,60"], "Project_Title": ["Ultra-Low Power and Highly-Scalable Interfaces for the Internet of Things"], "Total_Cost": ["EUR 247 728,60"], "Country": ["Italy"], "Project_ACR": ["ULPIoT"], "Technology_Description": "The era of the Internet of Things (IoT), in which every physical entity includes power-autonomous embedded electronics, capturing relevant information by sensors and interacting with objects and humans in a globally interconnected network, is bringing about new challenges in Integrated Circuit (IC) design. The performance of ICs in terms of integration density, power consumption and cost, in fact, is the only limiting factor to the feasibility and/or to the widespread diffusion of IoT-based solutions.", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-02-01"], "Project_ID": ["703988"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["POLITECNICO DI TORINO"], "EU_Contribution": ["EUR 244 269"], "Project_Title": ["Theranostic Injectable Hydrogel for Glioblastoma"], "Total_Cost": ["EUR 244 269"], "Country": ["Italy"], "Project_ACR": ["HyGlio"], "Technology_Description": "Glioblastoma multiforme (GBM) is the most frequent brain tumor in adults and is characterized by invariably fatal prognosis. Although the incidence of GBM is less than 10 to 100,000, the median survival of approximate 1 year from diagnosis makes it a considerable socio-economic burden. The presence of biological barriers for effective drug transport to the brain, the strong migrating-ability of the tumor and its rapid evolution into more aggressive and treatment-resistant variants, make GBM extremely hard to treat with traditional systemic chemotherapy. The HyGlio project proposes an ambitious bottom-up approach to build a multifunctional tool for long-term imaging and treatment of GBM, combining multiple treatment strategies, patient-specificity, and BBB bypassing in an all-in-one system. The system combines the advantages of: (i) Intracranial treatment, which maximizes efficacy while minimizing side effects; (ii) mild gelling conditions of the hydrogel, which reduce potential damages to the healthy tissue; (iii) increased drug penetration and selectivity due to the use of targeted polymer nanoparticles; (iv) Inhibition of molecular mechanisms involved in GBM spreading and aggressiveness; (iv) theranostic potential, due to the presence of magnetic resonance imaging, agents for rapid therapy adjustment according to patient\u2019s needs.", "To": ["2019-09-29, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-30"], "Project_ID": ["658665"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE UNIVERSITY OF NOTTINGHAM", "UNIVERSITY OF BATH", "POLITECNICO DI TORINO", "TECHNISCHE UNIVERSITEIT DELFT", "ISTITUTO NAZIONALE DI GEOFISICA E VULCANOLOGIA", "FUGRO INTERSITE BV", "GEO++ GESELLSCHAFT FUR SATELLITENGESTUTZTE GEODATISCHE UND NAVIGATORISCHE TECHNOLOGIEN MBH", "NOVELTIS SAS", "DEIMOS ENGENHARIA S.A."], "EU_Contribution": ["EUR 3 386 593,80"], "Project_Title": ["Training REsearch and Applications network to Support the Ultimate Real time high accuracy EGNSS solution"], "Total_Cost": ["EUR 3 386 593,80"], "Country": ["United Kingdom", "United Kingdom", "Italy", "Netherlands", "Italy", "Netherlands", "Germany", "France", "Portugal"], "Project_ACR": ["TREASURE"], "Technology_Description": "TREASURE will provide specialist training in the strategic and emerging area of European GNSS. ", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["722023"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["UNIWERSYTET MEDYCZNY W BIALYMSTOKU"], "EU_Contribution": ["EUR 1 569 600"], "Project_Title": ["International Interdisciplinary PhD studies in Biomedical Research and Biostatistics. Supporting the career and training in omic-based research and biostatistics by inter-national and-sectoral mobility"], "Total_Cost": ["EUR 3 139 200"], "Country": ["Poland"], "Project_ACR": ["ImPRESS"], "Technology_Description": "The aim of the project is to launch Interdisciplinary PhD Studies in Biomedicine aimed at young aspiring scientists, who will conduct research on life-style diseases and on biostatistics and bioinformatics methods necessary to process and interpret data obtained in research projects. The studies will provide an outstanding opportunity for in-depth education in high-throughput experimental and computational techniques used in genomics, proteomics, metabolomics and immunology. 15 PhD students will be involved in scientific projects supervised by excellent researchers, outstanding scientists selected from partner organizations, with a profound expertise and experience in: Cancer/Mutagenesis, Cardiovascular diseases, Population Medicine and Epidemiology, Diabetes/Obesity, Metabolic and Neurodegenerative diseases, Regenerative medicine, Molecular Biology, Genomics, Protein Analysis and Proteomics, Metabolomics/Lipidomics, Immunology and Experimental Medicine. They will be employed at Medical University of Bialystok. The development of doctoral students' research potential will be based also on internships, short research visits, conferences and trainings at the partner institutions: CEMBIO San Pablo University, Vienna Biocenter, Spanish National Center for Cardiovascular Research CNIC, Bialystok University of Technology and CenStat at Hasselt University. Industry partner organizations: Agilent Technology, deCODE, ideas4biology and Warsaw Genomics will invite PhD students for scientific visits, to familiarize young researchers with the tools and methods of work and organizational environment in the company. Industry providing their know-how will educate, and prepare their potential employees with high qualifications to get job in the close future. Best young scientists from the beginning of their academic career will be able to gain scientific independence and will have huge motivation to become more involved and creative in the research projects carried out thanks to COFUNDing the project by EC.", "To": ["2023-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2016 - Co-funding of regional, national and international programmes"], "Funding_scheme": ["MSCA-COFUND-DP - Doctoral programmes"], "Coordinated_in": ["Poland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["754432"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2016"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI TORINO", "POLITECNICO DI TORINO", "UNIVERSITA DEGLI STUDI DEL PIEMONTE ORIENTALE AMEDEO AVOGADRO", "UNIVERSITA DEGLI STUDI DI SCIENZE GASTRONOMICHE", "CENTROSCIENZA ONLUS ASSOCIAZIONE", "CREATIVA IMPRESA DI COMUNICAZIONE SRL"], "EU_Contribution": ["EUR 178 250"], "Project_Title": ["Cementing Links between Science and society toward Engagement and Responsibility"], "Total_Cost": ["EUR 271 750"], "Country": ["Italy", "Italy", "Italy", "Italy", "Italy", "Italy"], "Project_ACR": ["CLoSER"], "Technology_Description": "The European Researchers\u2019 Night (ERN) has become an annual tradition in Piedmont thanks to an extraordinary 10 years experience that has made citizens of all ages eagerly awaiting this appointment with the scientific vocation of our district and the European Commission.", "To": ["2018-01-01, closed project"], "Meta": [""], "Topic_s": ["MSCA-NIGHT-2016 - European Researchers' Night"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-05-02"], "Project_ID": ["722749"], "Call_for_Proposal": ["H2020-MSCA-NIGHT-2016"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI TRENTO", "PANEPISTIMIO PATRON", "UNIVERSITA DEGLI STUDI DEL SANNIO", "UNIVERZA V LJUBLJANI", "POLITECHNIKA SLASKA", "UNIVERSITA DEGLI STUDI ROMA TRE", "INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE RENNES", "ARCELORMITTAL BELVAL & DIFFERDANGE SA", "COLUMBIAN CARBON EUROPA SRL", "VCE VIENNA CONSULTING ENGINEERS ZT GMBH"], "EU_Contribution": ["EUR 3 393 811,98"], "Project_Title": ["EXTREME LOADING ANALYSIS OF PETROCHEMICAL PLANTS AND DESIGN OF METAMATERIAL-BASED SHIELDS FOR ENHANCED RESILIENCE"], "Total_Cost": ["EUR 3 393 811,98"], "Country": ["Italy", "Greece", "Italy", "Slovenia", "Poland", "Italy", "France", "Luxembourg", "Italy", "Austria"], "Project_ACR": ["XP-RESILIENCE"], "Technology_Description": "The tremendous impact of natural hazards, such as earthquakes, tsunamis, flooding, etc, which triggered technological accidents, referred to as natural-technological (NaTech) events, was demonstrated by: i) the recent Tohoku earthquake and the following Fukushima disaster in 2011; ii) the UK\u2019s 2015 winter floods which topped \u00a35bn, with thousands of families and businesses that faced financial problems because of inadequate or non-existent insurance. The NaTech problem is quite relevant as up to 10% of industrial accidents, involving the release of Chemical, Biological, Radiological, Nuclear and high-yield Explosives (CBRNE) substances, were triggered by natural hazards. To implement and support the Seveso II Directive 2012/18/EU which regulates the control of major accident hazards involving dangerous substances, XP-RESILIENCE intends to establish a network of individual research projects working towards Advanced Modelling and Protection \u2013via metamaterial-based isolators/layouts- of Complex Engineering Systems for Disaster Reduction and Resilient Communities. In fact, today there is a stronger need than ever to grow researchers that combine a robust academic foundation in reliability/resilience with practical experiences, technological expertise with awareness of the socio-economical context and conviction to furthering research with an entrepreneurial spirit. Hence, the objective of XP-RESILIENCE is to offer innovative research training ground as well as attractive career development and knowledge exchange opportunities for Early Stage Researchers (ESRs) through cross-border and cross-sector mobility for future growth in Europe. XP-RESILIENCE is an inter/multi-disciplinary and intersectoral programme as it includes seven academic partners, one Institute of Applied Science and seven private companies from ten different European countries.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-09-01"], "Project_ID": ["721816"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["CENTRE TECNOLOGIC FORESTAL DE CATALUNYA", "UNIVERSIDAD POLITECNICA DE MADRID", "Instituto Superior de Agronomia", "SVERIGES LANTBRUKSUNIVERSITET", "ITA-SUOMEN YLIOPISTO", "ALBERT-LUDWIGS-UNIVERSITAET FREIBURG", "UNIVERSIDADE DE EVORA", "CENTRO AGRONOMICO TROPICAL DE INVESTIGACION Y ENSENANZA CATIE", "The Pennsylvania State University", "UNIVERSITY OF WASHINGTON", "PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE", "UNIVERSIDADE DE SAO PAULO", "UNIVERSIDAD DE CHILE", "Pacific Northwest Research Station"], "EU_Contribution": ["EUR 1 885 500"], "Project_Title": ["Models and decision SUpport tools for integrated FOrest policy development under global change and associated Risk and UNcertainty"], "Total_Cost": ["EUR 1 885 500"], "Country": ["Spain", "Spain", "Portugal", "Sweden", "Finland", "Germany", "Portugal", "Costa Rica", "United States", "United States", "Chile", "Brazil", "Chile", "United States"], "Project_ACR": ["SuFoRun"], "Technology_Description": "Forest policy and decision makers are challenged by the need to balance the increasing demand for forest-based services (e.g. recreation, protection, conservation) and wood-based products (e.g. timber, fuelwood) with the foreseen scarcity of supply in different situations as for example disturbances (e.g. wildfires, droughts). Under these circumstances research on the impacts of different disturbances on the supply of services and goods is needed. To achieve these multipurpose forest managements and to integrate risk and uncertainty, New tools and models are needed. Furthermore, these tools and models may help to develop new policies that target the achievement of certain level of services while sustaining a certain level of goods supply. This project will take advantage of the knowledge on these topics in European and American organizations. It will further serve to exchange and generate knowledge on multipurpose forests, addressing risk and uncertainty as well as to strengthen research collaboration through active networking, staff exchange and dissemination activities between the participants.", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2016-02-01"], "Project_ID": ["691149"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["AALTO-KORKEAKOULUSAATIO", "ELEKTA OY", "HELSINGIN JA UUDENMAAN SAIRAANHOITOPIIRIN KUNTAYHTYM\u00c4", "PHYSIKALISCH-TECHNISCHE BUNDESANSTALT", "TECHNISCHE UNIVERSITAET ILMENAU", "UNIVERSITA DEGLI STUDI GABRIELE D'ANNUNZIO DI CHIETI-PESCARA", "Teknologian tutkimuskeskus VTT Oy"], "EU_Contribution": ["EUR 3 998 793"], "Project_Title": ["Breaking the Nonuniqueness Barrier in Electromagnetic Neuroimaging"], "Total_Cost": ["EUR 3 998 793"], "Country": ["Finland", "Finland", "Finland", "Germany", "Germany", "Italy", "Finland"], "Project_ACR": ["BREAKBEN"], "Technology_Description": "By combining accurate magnetic measurements of neural activity with near-simultaneous high-definition measurements of cerebral structure \u2013 provided by novel methods in ultra-low-field magnetic resonance imaging (ULF MRI ) \u2013 we will be able to image the dynamics of human brain function at unprecedented resolution and reliability. BREAKBEN will achieve a revolution in neuroimaging; we aim at breaking the barrier for measurement of neuronal currents by ULF MRI (neural current imaging; NCI) as well as breaking the nonuniqueness barrier for magnetoencephalography (MEG) by combining it with ULF MRI and accurately presented a priori information. A key aspect in utilizing the a priori information is injected current density imaging (CDI), which will inform us about the individual conductivity structure of the head. Using novel verification and validation approaches, we will demonstrate the unique advantages of these multimodal techniques. These breakthroughs will result in completely different workflows in brain imaging, also suitable for clinical use. We believe that we are at the edge of a qualitative technology jump with ULF MRI, its applications and combinations. This will lead to a wealth of new applications and revolutionize the way we do magnetism-based measurements of the nervous system. Europe has the unique chance to lead this revolution.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-1-2014 - FET-Open research projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2016-01-01"], "Project_ID": ["686865"], "Call_for_Proposal": ["H2020-FETOPEN-2014-2015-RIA"]}, -{"Partners": ["FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS"], "EU_Contribution": ["EUR 164 653,20"], "Project_Title": ["House Architecture and Heritage in modern Crete"], "Total_Cost": ["EUR 164 653,20"], "Country": ["Greece"], "Project_ACR": ["HArchitHeC"], "Technology_Description": "Cretan minor built heritage dating back to the Venetian and Ottoman periods has until now received scarce attention by scholars and local authorities. The two-year HArchitHeC project (House Architecture and Heritage in modern Crete) wants to focuses on rural and urban houses of Crete in order to reach three main goals: to perceive the built environment in its materiality and its historical evolution; to study how the evolution and interaction of Venetian and Ottoman cultural models built up a hybrid architecture in a colonial dimension; and to identify possible strategies for heritage protection by bringing research to the public realm. To do so, an interdisciplinary innovative approach will be used: a historical study of written sources and an architectural comparative study, by means of an inventory and a comparative study of Venetian and Turkish house prototypes. Such a pilot project aspires to a wider comparative study between Crete and the nearby regions, starting with other Mediterranean islands (Rhodes and Cyprus at first).", "To": ["2018-05-31, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Greece"], "Activity": ["Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555"], "From": ["2016-06-01"], "Project_ID": ["705499"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["FUNDACIO CENTRE DE RECERCA EN EPIDEMIOLOGIA AMBIENTAL - CREAL", "FUNDACION PRIVADA INSTITUTO DE SALUD GLOBAL BARCELONA"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Air Pollution, Growing brAin and cognitive disordeR in children"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain", "Spain"], "Project_ACR": ["APGAR"], "Technology_Description": "Air pollution exposure has been associated with adverse effects on cognition in children. However, the impact of air pollution on the structures and functions of the growing brain in children is unknown. The objectives of the APGAR project are to determine 1) the impact of urban air pollution on the structures and functions of the growing brain in children from the general population, 2) to what extent these structural and functional changes are associated with cognitive performance in children. The APGAR project is a longitudinal study conducted in 400 school age children from the general population, recruited between 2012 and 2013, in different schools in Barcelona, Spain. Psychometric and air pollution measurements were conducted weekly during 2 six-week periods: at the beginning of the school year and 9 months later. Neuroimaging (High-resolution 3-dimensional Magnetic Resonance Imaging (MRI), Diffusion Tensor Images, Fluid Attenuation Inversion Recovery, T2-weighted spin-echo sequences and functional MRI, spectrometry) were also conducted. Interfacing neuroimaging and environmental epidemiology represents an innovative applications of neuroimaging in general population, as previous studies have focused exclusively on effects based on test scores. Using original statistical methods (combination of supervised machine learning methods, feature selection and regression models), we will examine the impact of air pollution on the brain structures correlated with cognitive performance in children. Secondly, we will examine whether profiles of brain changes, specifically related to air pollution exposure, are associated with cognition level in participants. This multidisciplinary project may improve our understanding of the mechanisms that underlie the link between air pollution and cognitive disorder in children, and may lead to public health actions to improve air quality and reduce the burden of disease associated with air pollution in Europe.", "To": ["2017-10-14, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2015-10-15"], "Project_ID": ["656294"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["HASKOLI ISLANDS", "HASKOLI ISLANDS"], "EU_Contribution": ["EUR 1 998 543,75"], "Project_Title": ["The Genetics of Morbidity and Survival in Response to Significant Life Stressors"], "Total_Cost": ["EUR 1 998 545"], "Country": ["Iceland", "Iceland"], "Project_ACR": ["StressGene"], "Technology_Description": "Significant life stressors \u2013 including death of loved ones, being diagnosed with a life-threatening illness, and exposure to natural disasters or violence \u2013 are well-documented risk factors of ill health, disability and premature mortality. Why some individuals remain healthy while others remiss to adverse symptoms, disease or death after exposure to such life stressors remains unclear. The overarching aim of this research program is to advance current understanding of the potential genetic contribution to varying trajectories of health following exposure to significant life stressors. ", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Iceland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["726413"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["POLITECNICO DI TORINO", "POLITECNICO DI TORINO"], "EU_Contribution": ["EUR 149 526"], "Project_Title": ["ToothPic, a large-scale camera identification system based on compressed fingerprints"], "Total_Cost": ["EUR 149 526"], "Country": ["Italy", "Italy"], "Project_ACR": ["ToothPic"], "Technology_Description": "The continuously growing amount of photos posted and distributed over the Internet poses several important problems related to improper use of images, such as exploiting them for commercial purposes, re-posting others\u2019 photos without consent or infringing copyright, posting photos containing unethical or illegal contents, and so forth. Camera identification, which refers to identifying which digital imaging sensor has shot a given picture, exploiting the fact that each sensor leaves a unique fingerprint in all pictures, is a key ingredient in the solution to the aforementioned problems. The ToothPic project aims at validating a breakthrough camera identification technology developed during ERC starting grant \u201cCRISP\u201d. This technology is based on a novel compressed fingerprint format and outperforms state-of-the art techniques by orders of magnitude in terms of storage requirements and identification speed. As a consequence, it enables the deployment of camera-identification services on an unprecedented scale, paving the way for application to popular image sharing and social media sites. The proof-of-concept will consist in a very high-speed implementation of the camera identification core functionality, which will be used to validate the capability of the proposed technology to handle scenarios involving 100+ millions of sensor fingerprints, in real time and at a low cost. A set of demo applications, including a public search engine, taking as input a camera fingerprint or a photo and returning a list of photos acquired by the same camera, will also be implemented in order to raise a broad public interest and attract industries and venture capitalists. Upon successful validation, a European start-up company named \u201cToothPic\u201d will be created to commercialise the proposed technology.", "To": ["2017-02-28, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2014 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["665421"], "Call_for_Proposal": ["ERC-2014-PoC"]}, -{"Partners": ["FUNDACIO CENTRE DE RECERCA EN EPIDEMIOLOGIA AMBIENTAL - CREAL", "FUNDACION PRIVADA INSTITUTO DE SALUD GLOBAL BARCELONA"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Physical Activity, Inflammation and Respiratory health: an integrative analysis of biological, behavioural and environmental determinants"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain", "Spain"], "Project_ACR": ["PAIR"], "Technology_Description": "The link between physical activity with respiratory health and chronic obstructive pulmonary disease (COPD) remains weak and under-investigated. The limited existing research seems to suggest that systemic inflammation could lie in the causal pathway of this relationship, and that inflammatory-related conditions may modify this potential causal mechanism, although these hypotheses remain largely understudied. ", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2016-03-01"], "Project_ID": ["704268"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["MAX PLANCK INSTITUT FUR EISENFORSCHUNG GMBH"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Designing novel smart sensor interfaces based on a biologically abundant peptide motif: coiled-coils"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["smartCC"], "Technology_Description": "Smart interfaces alter their properties in response to an external trigger. Such devices open exciting opportunities for novel technologies with manifold applications. Electrical fields pose easily controllable triggers for smart interfaces and even allow a precise 'digital' switching between 'on' and 'off' states. The research project \u2018smartCC\u2019 will employ a biologically abundant class of biomacromolecules \u2013 coiled-coil peptides \u2013 to prepare smart selective interfaces, whose ability to specifically bind targets can be switched reversibly. Moreover, the produced interface will constitute a highly sensitive sensor by application of the attenuated total reflection infrared reflection technique. The variability of coiled-coils, employed in numerous biological systems, will also extend the potential application bandwidth of smart interfaces significantly. Molecular details of the switching and binding behaviour of the coiled-coils at the interface will be studied to test the feasibility of the envisioned working principle. Furthermore, the novel devices will be tested for an application with industrial relevance. To reach the goals of \u2018smartCC\u2019 a highly interdisciplinary approach is chosen that includes cooperation between three academic and one non-academic European partners. Thus, the implementation of this project will support bringing an emerging technology towards an economical benefit, foster intra European collaborations and mobility as well as strengthen Europe\u2019s scientific sector.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations"], "From": ["2017-06-01"], "Project_ID": ["705857"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["ECOLE POLYTECHNIQUE", "ECOLE POLYTECHNIQUE", "UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6"], "EU_Contribution": ["EUR 1 165 625"], "Project_Title": ["Statistical modelling across price and time scales: a quantitative approach to modern financial regulation"], "Total_Cost": ["EUR 1 165 625"], "Country": ["France", "France", "France"], "Project_ACR": ["STAQAMOF"], "Technology_Description": "This project aims at providing a new quantitative approach to financial regulation, notably in the context of high frequency trading. The key idea of our method is to build relevant statistical models through price and time scales, connecting the microstructure of financial markets to the long term behavior of prices. Doing so, we will be able to understand and quantify the macroscopic consequences of regulatory measures modifying the microscopic design of the market. Succeeding in this modelling task will require to address several intricate statistical problems. In particular new results will be needed in the fields of limit theory for semi-martingales, multifractal processes, rough stochastic differential equations, Hawkes processes and high-dimensional statistics. Hence, through this project, we not only have the hope to provide groundbreaking tools for worldwide regulation of financial markets but, concurrently, to answer important and challenging mathematical problems. In term of analyzing concrete regulatory measures, particular attention will be devoted to the issue of the choice of a proper tick value, that is the minimal price increment allowed on a financial market. Indeed, the tick value is the tool which seems to be favored by most policy makers in order to regulate high frequency trading.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["679836"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Information from Symbols and Illustrations: how to get it without vision"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["InSIght"], "Technology_Description": "In everyday life individuals are bombarded with symbols and illustrations: \u2018poisonous\u2019, \u2018flammable\u2019, \u2018fire evacuation route\u2019 etc.; however this life-saving information is not accessible to all of us.", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["657440"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 1 497 257"], "Project_Title": ["Vibronic control of organic electronic devices"], "Total_Cost": ["EUR 1 497 257"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom"], "Project_ACR": ["VIBCONTROL"], "Technology_Description": "Organic electronics (OE) is an expanding research field that exploits the electronic functionalities of organic molecules to make them robust and cost-efficient building blocks for future electronic devices. Due to the \u2018soft\u2019 character of organic materials, their electronic properties are defined by vibronic coupling (VC) phenomena which are a result of the interaction between electron and nuclear dynamics of the molecule.", "To": ["2020-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-06-01"], "Project_ID": ["639750"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["THE UNIVERSITY OF WARWICK", "THE UNIVERSITY OF WARWICK", "UNIVERSITA DELLA SVIZZERA ITALIANA", "ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA"], "EU_Contribution": ["EUR 2 492 033"], "Project_Title": ["Diversity and Performance: Networks of Cognition in Markets and Teams"], "Total_Cost": ["EUR 2 492 033"], "Country": ["United Kingdom", "United Kingdom", "Switzerland", "Italy"], "Project_ACR": ["BLINDSPOT"], "Technology_Description": "Contemporary organizations face three interrelated, but analytically distinguishable, challenges. First, they should be alert to mistakes that could be catastrophic. Second, they need to allocate attention, especially to correct past mistakes and to make accurate predictions about future developments. Third, they should be innovative, able to stand out from existing categories while being recognized as outstanding. This project investigates these cognitive challenges with the aim of developing a comprehensive sociological approach to study the social properties of cognition. Research on error detection, attention allocation, and recognizant innovation will be conducted in three distinct settings strategically chosen so the scale and complexity of the performance challenges increases across the cases. The research question that cuts across the socio-cognitive challenges asks whether and how diversity contributes to performance. 1) We first test whether social context, understood at the most basic level as the composition of a small collectivity, affects the cognitive activity of pricing. To do so, I use experimental market methods to test whether ethnic and gender diversity deflate price bubbles by disrupting herding behaviour. 2) The second study tests how the social structure of attention affects valuation. The activities involve error correction and accuracy of prediction in estimates by securities analysts; the method is two-mode network analysis; and the timing, intensity, and diversity of attention networks are the effects to be tested. 3) Whereas my first two tests examine relations among competitors, my third examines relations within and across collaborative teams. In studying the network properties of creativity, the challenge is recognizant innovation, the activity involves recording sessions in the field of music, the method is cultural network analysis, and the effects to be tested are the combined effects of stylistic diversity and social structure.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["695256"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION"], "EU_Contribution": ["EUR 175 419,60"], "Project_Title": ["Detection of visual motion in the cortex"], "Total_Cost": ["EUR 175 419,60"], "Country": ["Switzerland"], "Project_ACR": ["Cortical circuits"], "Technology_Description": "Direction selectivity is a feature of selected neurons in the visual cortex that is conserved in evolution. The emergence of cortical direction selectivity has been extensively studied but its circuit mechanism is still debated. My goal is to understand the circuit mechanism of cortical direction selectivity that is independent of retinal direction selectivity. I plan to approach this by using two animal models in which retinal direction selectivity has been disrupted. I will investigate the neuronal circuits of those cortical direction-selective neurons which retain their specificity in these animal models by performing single-cell-initiated functionalized rabies tracing and single-cell electrophysiological recordings. I will ask the three following questions: Do axon terminals of the principal cells of the lateral geniculate nucleus (LGN) fully lose direction selectivity after the abolishment of retinal direction selectivity, or could cortical feedback from layer 6 entrain direction selectivity in a subset of LGN cell axon terminals? What is the synaptic input profile underlying retina-independent cortical direction selectivity in pyramidal neurons? What is the contribution of the local presynaptic networks to the direction-selective tuning of pyramidal neurons with retina-independent cortical direction selectivity? This work will provide insights into how cortical selectively for environmental features arises.", "To": ["2020-08-31, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Research Organisations"], "From": ["2018-09-01"], "Project_ID": ["747836"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "MEDIZINISCHE UNIVERSITAET WIEN", "LUDWIG BOLTZMANN GESELLSCHAFT GMBH", "Masarykova univerzita", "EBERHARD KARLS UNIVERSITAET TUEBINGEN", "UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA", "INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE", "CHARITE - UNIVERSITAETSMEDIZIN BERLIN", "UNIVERSITA DEGLI STUDI DI TORINO", "JUSTUS-LIEBIG-UNIVERSITAET GIESSEN", "INSTITUT GUSTAVE ROUSSY", "GOETEBORGS UNIVERSITET", "UNIVERSITAETSKLINIKUM FREIBURG"], "EU_Contribution": ["EUR 3 849 199,56"], "Project_Title": ["ALK Activation as a target of TRAanslational Science (ALKATRAS): Break free from cancer"], "Total_Cost": ["EUR 3 849 199,56"], "Country": ["United Kingdom", "Austria", "Austria", "Czech Republic", "Germany", "Italy", "France", "Germany", "Italy", "Germany", "France", "Sweden", "Germany"], "Project_ACR": ["ALKATRAS"], "Technology_Description": "This ETN is embedded into an established international research programme; The European Research Initiative on Anaplastic Lymphoma Kinase (ALK)-related malignancies (ERIA; www.erialcl.net) is an existing and functional network of 13 partners, which will cosset and nurture a cohort of early stage researchers to become confident, competent, independent and well-connected European scientists with excellent career perspectives. ERIA was instigated to coordinate research into ALK-related malignancies to facilitate the development of less-toxic and more efficacious therapies. ALK is increasingly recognised as a prevalent oncogene in a number of human malignancies and therefore poses a prominent clinical problem, which requires coordinated research into its oncogenic mechanisms. ERIA now conducts a collaborative multidisciplinary research programme at the interface of biomedical and bio-mechanistic approaches, which will be an excellent environment to train the next generation of European scientists. The 15 recruited fellows will be incorporated into international academic study groups (all partners of the ERIA network) to perform high calibre research and also will be exposed to environments from other sectors to broaden their experience. Secondments will include technical training within individual laboratories and SMEs (TissueGnostics, Galkem, Cambridge Life Sciences, Sofigen and Varionostics) as well as large Pharma (Roche). Training through research will be complemented with a balanced programme of transferable skills and access to local courses. The training of each fellow will be guided by a personal career development plan and supervised by a PhD committee panel. The primary goal of the network is to train the recruited fellows by participation in an internationally competitive research programme and integrating them into an international network. Thereby providing competence in state-of-the-art research and development at the forefront of translational science.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["675712"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["FUNDACIO CENTRE DE RECERCA EN EPIDEMIOLOGIA AMBIENTAL - CREAL", "FUNDACION PRIVADA INSTITUTO DE SALUD GLOBAL BARCELONA"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Engaging Citizens in Science: Promoting the Viability of Participatory Sensing for Monitoring Air and Environmental Quality"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain", "Spain"], "Project_ACR": ["ESAIRE"], "Technology_Description": "Participatory sensing initiatives for monitoring air and environmental quality are flourishing as a result of the citizens\u2019 growing concern about pollution. Scientific teams and Do it Yourself communities are developing personal sensor kits and data aggregation platforms, leveraging smartphones to gather environmental data. However, the human and social aspects that have the power to sustain these citizen science projects do not receive enough attention.", "To": ["2017-03-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2015-04-01"], "Project_ID": ["656439"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["LUDWIG BOLTZMANN GESELLSCHAFT GMBH", "LUDWIG BOLTZMANN GESELLSCHAFT GMBH"], "EU_Contribution": ["EUR 1 499 500"], "Project_Title": ["Common Oncogenic Mechanisms in Multi-Partner Translocation Families in Acute Myeloid Leukemia"], "Total_Cost": ["EUR 1 499 500"], "Country": ["Austria", "Austria"], "Project_ACR": ["ONCOMECHAML"], "Technology_Description": "Acute Myeloid Leukemia (AML) is the most frequent cancer of the blood system, with >80% mortality within 5 years of diagnosis. Straightforward clinical decisions are complicated by the genetic complexity of AML. In particular, fusion proteins arising from chromosomal aberrations are recurrently found in AML and often act as strong driver oncogenes. In \u201cMulti-Partner Translocation\u201d (MPT) families, one specific gene is fused to many recipient loci. Due to this modular architecture, MPT families are of particular interest to comparative studies of oncogenic mechanisms. The three most common MPT families in AML represent translocations of the MLL, RUNX1 and NUP98 genes. Despite their clinical significance, the molecular mechanism of transformation remains unknown for the majority of fusion proteins and it is unclear if transforming mechanisms are conserved within and across different MPT families.", "To": ["2020-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Austria"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2015-06-01"], "Project_ID": ["636855"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN", "ARISTOTELIO PANEPISTIMIO THESSALONIKIS", "UNIVERSITY OF ULSTER", "OULUN YLIOPISTO", "SALUMEDIA TECNOLOGIAS SL", "Chambre de Commerce et d'Industrie de Grenoble", "BEACON HOSPITAL SANDYFORD LIMITED", "PHILIPS ELECTRONICS NEDERLAND B.V."], "EU_Contribution": ["EUR 3 950 971,20"], "Project_Title": ["Connected Health Early Stage Researcher Support System"], "Total_Cost": ["EUR 3 950 971,20"], "Country": ["Ireland", "Greece", "United Kingdom", "Finland", "Spain", "France", "Ireland", "Netherlands"], "Project_ACR": ["CHESS"], "Technology_Description": "Changing demographics and increasing pressure on health related resources mean that new models of care must be found. Fortunately, technology developments and increasing digital literacy mean that we can now put the correct information in the correct hands at the correct time. This is connected health and it allows patients, clinicians, and planners to make better decisions. Ultimately, these decisions can save lives, save money and ensure a better quality of life for the patient during and after treatment.", "To": ["2019-08-31, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-09-01"], "Project_ID": ["676201"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["SVERIGES LANTBRUKSUNIVERSITET", "BIOBANKS AND BIOMOLECULAR RESOURCES RESEARCH INFRASTRUCTURE CONSORTIUM (BBMRI-ERIC)", "KAROLINSKA INSTITUTET", "UPPSALA UNIVERSITET", "UNIVERSITY OF THE WESTERN CAPE", "MAKERERE UNIVERSITY", "STELLENBOSCH UNIVERSITY", "CENTRE INTERNATIONAL DE RECHERCHE SUR LE CANCER", "International Livestock Research Institute", "MEDIZINISCHE UNIVERSITAT GRAZ", "INSTITUTE OF HUMAN VIROLOGY NIGERIA LTDGTE"], "EU_Contribution": ["EUR 2 001 250"], "Project_Title": ["Bridging Biobanking and Biomedical Research across Europe and Africa"], "Total_Cost": ["EUR 2 035 250"], "Country": ["Sweden", "Austria", "Sweden", "Sweden", "South Africa", "Uganda", "South Africa", "France", "Kenya", "Austria", "Nigeria"], "Project_ACR": ["B3Africa"], "Technology_Description": "B3Africa - Bridging Biobanking and Biomedical Research across Europe and Africa will dramatically improve and facilitate the development of better predictive, preventive and personalized healthcare worldwide. The rapidly evolving African biobanks are an invaluable resource: The African population has the greatest genomic diversity on the planet and represents an incredible resource of information to advance biomedical research. B3Africa aims to implement a cooperation platform and technical informatics framework for biobank integration between Africa and Europe. The collaboration harmonizes the ethical and legal framework, biobank data representation and bioinformatics pipelines for sharing data and knowledge among biobanks and allowing access for researchers from both continents. Main actors from the relevant initiatives including Human Heredity and Health in Africa project (H3Africa), European Biobanking and Biomolecular Resources research infrastructure (BBMRI-ERIC) and LMIC Biobank and Cohort Network (BCNet) collaborate in B3Africa to address the following objectives:", "To": ["2018-06-30, ongoing project"], "Meta": [""], "Topic_s": ["INFRASUPP-6-2014 - International cooperation for research infrastructures"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2015-07-01"], "Project_ID": ["654404"], "Call_for_Proposal": ["H2020-INFRASUPP-2014-2"]}, -{"Partners": ["EBERHARD KARLS UNIVERSITAET TUEBINGEN"], "EU_Contribution": ["EUR 239 860,80"], "Project_Title": ["Interacting relativistic quantum dynamics via multi-time integral equations"], "Total_Cost": ["EUR 239 860,80"], "Country": ["Germany"], "Project_ACR": ["Multi-time Integral Eqs."], "Technology_Description": "Multi-time wave functions are quantum-mechanical wave functions with N space-time arguments for N particles. They were suggested by the Nobel laureates Dirac, Tomonaga and Schwinger as a particularly natural way of achieving manifest Lorentz invariance in the Schr\u00f6dinger picture. While for a long time it was not clear how to obtain consistent interacting dynamics for multi-time wave functions, this has changed recently when a series of papers has clarified the theory of multi-time Schr\u00f6dinger equations and provided the first interacting toy models. This project aims, with the long-term goal of a rigorous multi-time formulation of quantum field theory in mind, at improving on these models by considering the possibility of integral equations to formulate interacting dynamics for multi-time wave functions of N=2 particles. This is especially promising, as integral equations avoid a restrictive consistency condition that one faces for differential multi-time equations. Furthermore, the typical ultraviolet divergencies of quantum field theory are avoided.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["705295"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSIDADE DO PORTO", "KATHOLIEKE UNIVERSITEIT LEUVEN", "UNIVERSITE DE STRASBOURG", "CHRISTOS PAPADOPOULOS & SIA O.E.", "LAZER SPORT NV", "CENTER FOR TECHNOLOGY RESEARCH AND INNOVATION (CETRI) LTD"], "EU_Contribution": ["EUR 1 350 000"], "Project_Title": ["Intersectoral Network for Innovation on Smart Thermal Solutions for Bicycle Helmets"], "Total_Cost": ["EUR 1 350 000"], "Country": ["Portugal", "Belgium", "France", "Greece", "Belgium", "Cyprus"], "Project_ACR": ["SmartHELMET"], "Technology_Description": "Bicycle helmets are a tremendously important asset against head injuries during accidents. However, their normal use is often associated with strong thermal discomfort due to the (thermally) insulating nature of the materials used in their structures. This affects directly the willingness to wear helmets, which has direct implications in terms of the risk to which riders are exposed to. However, the capacity and expertise to improve the thermal performance of helmets exist on academic institutions (e.g. expertise in thermal physiology, monitoring of bio-responses, active cooling) but they lack a viable supply chain to go from prototypes to finished products, ready for exploitation. On the other hand, SMEs lack the technical skills and research facilities to perform R&D activities, to solve the mentioned problem. To solve this intersectoral problem, the SmartHELMET project will create a sustainable ecosystem of collaboration and knowledge transfer between academic and industrial partners that will develop the next generation of bicycle helmets with smart thermal management. The project\u2019s innovative aspects in terms of new products, processes and applications are very significant, as the new knowledge has many potential applications in the development of other smart headgear products (e.g. motorcycle helmets, industrial protective headgear, sports related headgear, etc.) as well as smarts products in other sectors where the thermal aspect is crucial (e.g. protective garments, sports clothing and footwear). To achieve its objectives, SmartHELMET will put together research expertise and resources from three large academic partners with market, commercialization and innovation experience from three SMEs, to exchange knowledge through intersectoral staff secondments. The project will bridge research initiatives between the academic and industrial sectors, creating long-term cooperation between them, while raising society awareness about its implications for citizens.", "To": ["2019-02-28, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Portugal"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-03-01"], "Project_ID": ["645770"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["STICHTING CENTRUM VOOR WISKUNDE EN INFORMATICA", "BANCO SANTANDER SA", "VORTECH BV", "ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA", "UNIVERSIDADE DA CORUNA", "ANALISTAS FINANCIEROS INTERNACIONALES SA", "ERNST & YOUNG ACCOUNTANTS LLP", "TECHNISCHE UNIVERSITEIT DELFT", "NIER INGEGNERIA SPA", "UNIPOL GRUPPO FINANZIARIO SPA"], "EU_Contribution": ["EUR 1 522 617,12"], "Project_Title": ["Applied mathematics for risk measures in finance and insurance, in the wake of the crisis"], "Total_Cost": ["EUR 1 522 617,12"], "Country": ["Netherlands", "Spain", "Netherlands", "Italy", "Spain", "Spain", "United Kingdom", "Netherlands", "Italy", "Italy"], "Project_ACR": ["WAKEUPCALL"], "Technology_Description": "The EID WAKEUPCALL has been set up with the knowledge that, in the WAKE of the financial crisis, a reconsideration of fundamental assumptions that have been standard in the mathematical models for the valuation of financial and insurance products, like CALLs is taking place. The crisis alerted to reiterate models, assumptions and computations. It is now better understood that the usual paradigm, in which financial risks can be mitigated, spread, or even hedged away perfectly, is too simplistic for markets under stressed conditions. Lead by the Basel Committee on Banking Supervision, financial and insurance institutions are currently implementing new paradigms regarding risk management. Many of the updates in the risk measures involve sophisticated mathematics. In this sense, the crisis has provided important feedback on appropriate directions for the required mathematical improvements. As regards to hedging and risk mitigation, which are important steps in the risk management chain, nowadays even the hedging of basic financial instruments has become a complicated task. More sophisticated models are needed if hedging programs are to remain effective under financial stress.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-EID - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-EID)"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["Netherlands"], "Activity": ["Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["643045"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["PHILIPS ELECTRONICS NEDERLAND B.V.", "UNIVERSITAETSKLINIKUM AACHEN"], "EU_Contribution": ["EUR 766 122,84"], "Project_Title": ["Real time therapy planning for Thermal based therapy modalities in oncology care."], "Total_Cost": ["EUR 766 122,84"], "Country": ["Netherlands", "Germany"], "Project_ACR": ["AdapTT"], "Technology_Description": "AdapTT will unlock the potential for development of a real time adaptive therapy planning tool for thermal treatment in prostate oncology. Highly specialized and cost effective state-of-the-art scientific solutions can only be developed when complimentary partners of different sectors work synergistically. The intersectoral nature of the European Industrial Doctorates (EID) framework, between industry and academia, is a key requirement for success of the proposed PhD projects. Specific application knowledge on clinical software platforms development, imaging systems and therapy modalities of the industrial partner, has to be combined with fundamental biophysical knowledge and clinical need insights of the clinical academic partner. This combination of European based expertise is unique and being able to be exposed to these different research climates will strongly enhance the employability and career prospects of the early stage researchers (ESR\u2019s), participating in the program. ", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-EID - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-EID)"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["Netherlands"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2015-01-01"], "Project_ID": ["642445"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 245 185,70"], "Project_Title": ["Displacing Deviance: Second-Generation Migrant Youth, Disciplinary Return, and Transnational Social Fields of Inclusion and Exclusion return"], "Total_Cost": ["EUR 245 185,70"], "Country": ["United Kingdom"], "Project_ACR": ["2GENRETURN"], "Technology_Description": "\u2018Displacing Deviance\u2026\u2019 is a state-of-the-art research project into transnational family practices. It examines \u2018disciplinary return\u2019 - young second-generation migrants sent \u2018home\u2019 to their countries of heritage by their parents as a disciplinary measure \u2013 a widespread practice which has not yet been the focus of direct research. Second-generation ties to the homeland are critical to issues of integration, yet understanding of second-generation transnationalism is thin. Examining \u2018disiplinary return\u2019 within the Nigerian diaspora will establish new, in-depth understanding of how migrants navigate transnational structures of opportunity and constraint through their family practice. This will shed light on the relationship between socio-economic challenges faced in \u2018host\u2019 countries, and how migrants build loyalties and identities in a transnational context. It will produce findings of relevance to policy concerns about societal challenges around multicultural integration and minority youth in the education and criminal justice sectors. The research approach is innovative, answering calls for youth-centric, multi-sited, and intergenerational research into transnational families, thus far mostly studied via first-generation migrant parents in single locations. Qualitative research with migrant parents and youth, and participatory research with migrant youth, will be undertaken in the USA, Nigeria and the UK. Supervision by a world expert, Dr Coe at Rutgers, in the outgoing phase will provide a unique training opportunity for the researcher and excellent means to build networks. Expertise gained will be transferred back into Europe in the incoming phase by working with Dr Dwyer, co-director of the Migration Research Unit (Geography Department) at UCL, a hub for migration research with Europe-wide networks. This will maximise output which advance theoretical debates around migration and transnationalism, speak to policy debates, and capture public audiences.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["750495"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UPPSALA UNIVERSITET", "UPPSALA UNIVERSITET"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Spore killer genomics: elucidating causes and consequences of a fungal meiotic drive element"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["SpoKiGen"], "Technology_Description": "The traditional view of the genome is that of a highly coordinated network that has evolved to produce a successful individual. However, the alternative view of the genome as containing intrinsically conflicting parts that coevolve antagonistically, has recently emerged. Today, it is widely accepted that conflicts caused by selfish genetic elements is a driving force for evolutionary innovation, and hence, is of fundamental importance for all aspects of evolution. Nevertheless, empirical data on the topic is largely lacking. Here, I introduce the fungus Neurospora as a novel study system of the evolutionary significance of meiotic drive. In this sexual eukaryote model system, the meiotic drive element Spore killer is found. The cytological properties and natural distribution of Spore killing in Neurospora has been investigated for several decades, and preliminary data suggests that it is an important driver of both genome evolution and of higher-order evolutionary processes. The existing knowledge and resources of this system provide a foundation for the proposed research program, in which I plan to build a tool-kit of genomic and experimental resources to I) identify and characterize the gene(s) encoding Spore killer elements, II) assess the strength of Spore killer as a meiotic drive, III) unravel the evolutionary history of the Spore killer complex in Neurospora, IV) investigate the association between Spore killer and genome evolution, and V) analyze the role of Spore killer as a driver of speciation and mating system transitions. This research program will manifest the Spore killer as a primary and pioneering model for the study of meiotic drive, and profoundly impact our understanding of segregation distorters as drivers of eukaryote genome evolution. Furthermore, insights emerging from the project presented are conceptually important for basic evolutionary biology, in the study of natural selection acting at multitudinal levels in a biological hierarchy.", "To": ["2020-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-05-01"], "Project_ID": ["648143"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["UNIVERSITE DE BOURGOGNE"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Stalling the Replication Fork via the Impedimental Stabilization of Higher-order DNAs"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["STARFISH DNA"], "Technology_Description": "\"Cancer is a generic term for a group of diseases characterized by the uncontrolled growth and spread of cells with abnormal proliferating activity. Most of the anticancer drugs currently used in the clinic trigger irreversible DNA damages and thus, promote replicative stress. As an alternative of irreversible DNA strand breaks, the non-covalent small-molecule stabilization of unusual, non-B DNA structures has emerged as a promising way to create DNA damages. One of such non B-DNA structures is a three-way DNA junction that might fold both upstream and downstream of the replication fork. The stabilization of three-way junctions by small molecules therefore opens a promising way to induce replicative stress in a highly cancer-specific manner. The main goal of the project \"\"STARFISH DNA\"\" (for \"\"Stalling the Replication Fork via the Impedimental Stabilization of Higher-order DNAs\"\") is to identify a new series of compounds capable of creating DNA damages through three-way junction stabilization and to use them either as standalone therapeutic agent to fight against cancers or in combination with established drugs that disrupt cancer signaling pathways in a synergistic manner.\"", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["750368"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM", "ISTITUTO NAZIONALE DI RICERCA METROLOGICA", "HEINRICH-HEINE-UNIVERSITAET DUESSELDORF", "GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER", "PHYSIKALISCH-TECHNISCHE BUNDESANSTALT", "NPL MANAGEMENT LIMITED", "JRC -JOINT RESEARCH CENTRE- EUROPEAN COMMISSION", "UNIVERSITAET ULM", "THE UNIVERSITY OF NOTTINGHAM", "TELEDYNE E2V (UK) LIMITED"], "EU_Contribution": ["EUR 945 000"], "Project_Title": ["Quantum sensors - from the lab to the field"], "Total_Cost": ["EUR 945 000"], "Country": ["United Kingdom", "Italy", "Germany", "Germany", "Germany", "United Kingdom", "Belgium", "Germany", "United Kingdom", "United Kingdom"], "Project_ACR": ["Q-Sense"], "Technology_Description": "Q-SENSE will promote international and inter-sector collaboration for the advancement of science and the development of innovation in the area of cold atom quantum sensors. In particular it fosters a shared culture of research and innovation that turns the Nobel-prize winning ideas of cold atom research and precision measurement (Nobel prizes 1997 and 2005) into innovative products. In particular, we bring together a synergetic network of the world leaders in optical clocks and atom interferometers with technology translators and end user applicants to promote space and terrestrial applications of optical clocks and cold atom gravity sensors with an additional eye on implications on policies via the JRC. Our research and innovation programme will deliver knowledge exchange around a technology demonstrator for a space optical clock, development plans for atom interferometer satellite missions, an open source toolbox for simulations of atom interferometer performance in real-world applications and outreach to over 70 companies and the public raising awareness of the potential of optical clocks and cold atom gravimeters for economic and societal benefits, such as in global water monitoring, humanitarian de-mining, satellite navigation and broadband communication. Q-SENSE will enhance the skills of research- and innovation-related human resources in our partner organisations to work seamlessly across sectors and provide new career perspectives in the emerging area of commercial quantum technologies.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Paolo Antonio Mastroeni", "Tel.: +39-011-3919541", "Fax: +39-011-346384", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-01-01"], "Project_ID": ["691156"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["PANEPISTIMIO THESSALIAS", "UNIVERSIDADE DO PORTO", "IMEDICA SA", "CENTER FOR TECHNOLOGY RESEARCH AND INNOVATION (CETRI) LTD"], "EU_Contribution": ["EUR 828 000"], "Project_Title": ["Intersectoral collaboration for innovation in non-invasive techniques to estimate human brown adipose tissue activity"], "Total_Cost": ["EUR 828 000"], "Country": ["Greece", "Portugal", "Romania", "Cyprus"], "Project_ACR": ["ICI-THROUGH"], "Technology_Description": "Non-invasive, inexpensive, and accurate assessment of adipose tissue (BAT) activity is crucial in the fight against metabolic pandemics such as obesity, and in various industries (e.g., foods, pharmaceuticals). However, the only technique available to measure the activity of this tissue is PET/CT imaging of the glucosetracer 18F-fluorodeoxyglucose , a highly invasive technique that is harmful for human health, expensive, and requires extensive equipment and facilities. The development and validation of non-invasive and practical techniques to accurately estimate human BAT activity requires the creation of new technology and the advancement of the current state of the art. Companies (particularly SMEs) do not have the technical capabilities to conduct R&D activities at the level of excellence required for such development. Academic institutions have the capacity to conduct the necessary R&D but they lack the expertise to develop the prototype post project. To solve this intersectoral problem, the ICI-THROUGH project will create a sustainable innovation platform of intersectoral collaboration between two academic (UOT and UOP) and two industrial (IMED and CETRI) European participants to exchange knowledge on the development of non-invasive techniques to estimate human BAT activity. This will be achieved via a series of clear and measurable research and innovation objectives that will be realized via staff exchanges of experienced and early-stage researchers divided into: networking, research and training, workshop, innovation, dissemination, and public engagement activities. The ICI-THROUGH project is effectively aligned with the scope of the RISE call and its success is in the interest of all participants. Also, exploitation of the obtained tangible outcomes (e.g., prototype) will ensure the partnership\u2019s sustainability post project. Thus, the ICI-THROUGH project has high potential to become a self-sustaining innovation incubator between the four participants.", "To": ["2018-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Greece"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2014-12-01"], "Project_ID": ["645710"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["AARHUS UNIVERSITET"], "EU_Contribution": ["EUR 200 194,80"], "Project_Title": ["Impacts of Greenland Ice Sheet melt on primary productivity and carbon cycling in Greenland coastal ecosystems"], "Total_Cost": ["EUR 200 194,80"], "Country": ["Denmark"], "Project_ACR": ["GrIS-Melt"], "Technology_Description": "Due to recent anthropogenic climate warming, the Greenland Ice Sheet (GrIS) is melting at accelerating rates, increasing the freshwater content of the Arctic Ocean. Freshwater run-off from the GrIS influences circulation patterns and stratification of the water column and also introduces large fluxes of allochthonous organic and inorganic matter into the Greenland coastal environment, both of which have the potential to influence microbial carbon cycling. Changing patterns of circulation and stratification have the potential to effect water column mixing and thus nutrient supply to primary producers, while introduction of particles and suspended sediments can limit light availability to primary producers and provide increased surface area for bacterial activity. Recent studies also documented that GrIS melt water contains significant amounts of bioavailable organic carbon and nutrients, which could provide subsidies to the microbial community, but the impact is unknown. At present, studies have only quantified the effects of GrIS melt water on the physical and chemical environment of Greenland fjords, no studies have addressed the physicochemical effects of melt water and its allochthonous constituents on ecosystem carbon cycling, making it difficult to estimate how increased melting is altering the productivity regimes in coastal marine ecosystem around Greenland. Primary production is the base of the marine food web and supports commercial and sustenance fisheries along the Greenland coast. Melting of the GrIS is expected to intensify in the future. Thus, this project proposes a timely effort to determine the impact of GrIS melt water on productivity and carbon cycling in the Greenland coastal ecosystem, the results of which can be used by climate scientist and fisheries managers to predict the future productivity of an locally and globally important ecosystem.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["752325"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE"], "EU_Contribution": ["EUR 175 419,60"], "Project_Title": ["Increasing the robustness and neural integration of bidirectional prostheses for rehabilitation withrobust and real time Independent Component Analysis"], "Total_Cost": ["EUR 175 419,60"], "Country": ["Switzerland"], "Project_ACR": ["BIREHAB"], "Technology_Description": "Hand loss is a highly disabling event that markedly affects the quality of life. To achieve a close to natural replacement for the lost hand, the user should be provided with the rich sensations that are naturally perceive when grasping or manipulating an object. Ideal bidirectional hand prostheses should involve both a reliable decoding of the user\u2019s intentions and the delivery of nearly \u201cnatural\u201d sensory feedback through remnant afferent pathways, simultaneously and in real time. As such, much effort in the last decade has been directed towards the achievement of both the robust performance necessary for natural prosthesis control and the sensory feedback integration. Despite this however, researchers have struggled so far to translate their findings to clinical and commercial applications, as it is necessary first to develop robust multifunctional myoelectric control algorithms and to characterize the neurophysiological responses elicited by artificial sensory feedback. The first aim of BIREHAB is to characterize the cortical activity evoked by neuromorphic electrical stimulations of the median and ulnar nerve in amputees and compare it with healthy subjects\u2019s undergoing the same protocl. The second aim is to develop a new blind source separation algorithm (Independent Component Analysis) for the robust extraction of muscle synergies and Motor Unit Action Potentials from high density surface electromyogram. ICA will also be useful to overcome the current issues that impair the efficacy of myoelectric prostheses control, such as electrodes cross talk and volume conduction. The implementation of BIREHAB has the potential to aid in the personalization of post-stroke rehabilitation protocols, and to improve the long term efficacy, quality and neural integration of hand prostheses. These results may enable, in the near future, near-natural replacement of missing hands and will help devise new upper limb rehabilitation strategies.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["750947"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE BRITISH LIBRARY BOARD", "MONASH UNIVERSITY", "EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH", "DATACITE \u2013 INTERNATIONAL DATA CITATION INITIATIVE", "THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL", "EUROPEAN MOLECULAR BIOLOGY LABORATORY", "ELSEVIER BV", "ORCID EU", "UNIVERSITAET BREMEN", "PUBLIC LIBRARY OF SCIENCE"], "EU_Contribution": ["EUR 3 456 250"], "Project_Title": ["THOR \u2013 Technical and Human Infrastructure for Open Research"], "Total_Cost": ["EUR 3 458 250"], "Country": ["United Kingdom", "Australia", "Switzerland", "Germany", "United States", "Germany", "Netherlands", "Belgium", "Germany", "United States"], "Project_ACR": ["THOR"], "Technology_Description": "Five years ago, a global infrastructure to uniquely attribute to researchers their scientific artefacts (articles, data, software\u2026) appeared technically and socially infeasible. Since then, DataCite has minted over 3.5m unique identifiers for data. ORCID has deployed an open solution for identification of contributors with over 850,000 registrants in less than 2 years. ", "To": ["2017-11-30, closed project"], "Meta": [""], "Topic_s": ["EINFRA-7-2014 - Provision of core services across e-infrastructures"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Other", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Other"], "From": ["2015-06-01"], "Project_ID": ["654039"], "Call_for_Proposal": ["H2020-EINFRA-2014-2"]}, -{"Partners": ["IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["From CO2, Water and Sunlight to Valuable Solar Fuels: Tracking Reaction Intermediates in Solar Fuel Generation with Ultrafast Spectroscopy for More Efficient Catalysis"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["CO2 Intermediates"], "Technology_Description": "Fundamental understanding of the catalytic chemistry and underlying mechanisms in carbon dioxide (CO2) reduction is an urgent need for efficient solar energy conversion from CO2, water and sunlight to valuable carbon-neutral fuels that urgently need to replace our fossil fuel-based economy of today. This proposal focuses on unraveling the reaction mechanisms of the reduction of CO2 in aqueous photoelectrochemical (PEC) systems in order to allow innovative development of more efficient chemistry for the production of solar fuels based on the understanding of the underlying mechanisms. ", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["749231"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE SAINSBURY LABORATORY"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Dynamic interplay between phosphorylation and ubiquitination during plant receptor kinase-mediated immunity"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["PHOSPH-UBIQ-IMMUN"], "Technology_Description": "The first layer of plant immunity is mediated by the recognition of conserved microbial features known as pathogen-associated molecular patterns (PAMPs) by plasma membrane-localized pattern recognition receptors (PRRs). An immediate downstream substrate of activated PRR complexes is the cytoplasmic kinase BIK1, which is a positive regulator of PAMP-triggered immunity (PTI). The objective of this proposal is to uncover how BIK1 regulates plant immune signalling via the characterization of its substrates in PTI. The host laboratory has recently identified a potential BIK1 phosphorylation motif, which is present in 22 Arabidopsis proteins that are rapidly phosphorylated upon PAMP treatment. Eight of these proteins have been confirmed as true BIK1 phosphorylation substrates and include several proteins involved in protein ubiquitination/deubiquitination, including an E3 ubiquitin ligase and two ubiquitin specific proteases (USPs), which will be the focus of this study. Preliminary data indicate that the E3 ubiquitin ligase is a positive regulator of PTI. Here, I will further characterize the role of this E3 ubiquitin ligase in PTI by characterising the role of its phosphorylation by BIK1, and identifying its substrates and their role in PTI using genetic and biochemical approaches. A similar approach will be used to decipher the role of the two USPs in PTI. The project will directly benefit from my previous experience in working with deubiquitinating enzymes during plant development, which will provide all the necessary technical and theoretical knowledge to ensure the project\u2019s success. This exciting project will allow me resuming my career in science, thus corresponding to the objectives of the People Work Programme. At the end of the project, we will have a better understanding on how activated PRR complexes regulate downstream immune signalling, which is a very important question in innate immunity, in both plants and mammals.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations"], "From": ["2017-07-01"], "Project_ID": ["753641"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CARL VON OSSIETZKY UNIVERSITAET OLDENBURG"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Dark Ocean Cosmeceuticals -DOC-: The Cosmetical and Pharmaceutical Potential of Marine Dissolved Organic Matter"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["DOC"], "Technology_Description": "An ageing population as well as chronic and infectious diseases, pandemic threats and antimicrobial resistance are currently on the rise. As a consequence, increasing attention is paid to the development of novel drugs, treatments and personal care products. In this context, blue biotechnology offers an opportunity to explore the potential of the marine microbial world to produce biological active metabolites, which may support health and wellbeing. The general goal of this proposal is the extraction and identification of biologically active substances in one of the largest reservoirs of organic material on Earth: the recalcitrant marine dissolved organic matter (RDOM) pool. This pool is an unexplored potential source of bioactive substances. For this purpose, the RDOM will be extracted from (1) one of the oldest water masses of the global ocean located at intermediate depths of the North Pacific and (2) the reworked DOM of marine sediments porewater in the North Sea. A comparative screen will be performed with the more recent surface oceanic water of the North Pacific. The antioxidant, immunostimulant and antitumoral potential of these DOM samples will be explored to evaluate possible cosmetical and pharmaceutical suitability. The DOM molecular diversity and features identified by mass spectrometry and nuclear magnetic resonance will be correlated with the different modes of bioactivity. This proposal will enable Dr. Catal\u00e1 to broaden her expertise on molecular characterization of the DOM pool, to learn new methodologies of bioactive substances identification as well as to meet future challenges on marine natural product research, endorsed by the H2020 Societal Challenges of 'Health, Demographic Change and Wellbeing' and 'Marine Research and the Bioeconomy'. This combination of expertise is unique, and thus will be a milestone in Dr. Catal\u00e1 career towards an independent scientist of high international visibility.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["749586"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["GaTHeR, Gender and Transfer of Knowledge in Hunter Gatherer Research"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["GaTHeR"], "Technology_Description": "This project analyses feminist knowledge transfer in mainstream Science. Following the European Research Area key priority of strengthening the Gender dimension in research programs, the goal of this research is building a methodology to better understand the relations between Knowledge Production, Gendered Organisations and Methodological Challenges through a multidisciplinary case-study; hunter-gatherer (HG) research. ", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-06-01"], "Project_ID": ["750640"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAT AUTONOMA DE BARCELONA"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Social Vulnerability and its Intersections: The role of gender in a comparative perspective"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["VINe"], "Technology_Description": "VINE seeks to disentangle the multidimensionality of the risk of social exclusion, focusing on vulnerable populations; specifically, those individuals who are in a fragile condition with regard to integration into the domains of well-being (family, labour market, welfare state). Using EU-SILC microdata, the project analyses the interactions between social vulnerability and different individual characteristics that might magnify it. Secondly, the project intends to study how, and in what ways, these individual characteristics combine to determine economic insecurity at household level. The main contribution of this project is proposing an analysis of how the institutional context as well as individual characteristics affects individual risk of living in vulnerable households, from a comparative and multidimensional perspective. By comparing six European countries, as representatives of different institutional environments, the VINE project aims to deliver a better understanding of the causes and mechanisms that determine both men and women\u2019s exposure to social vulnerability. The innovation herein is the assumption that gender is the main analytical dimension in interactions, when theorised according to the intersectional perspective. With a multi-dimensional explorative analysis, and multinomial logistic regression, the analysis will lead to the development of a synthetic indicator of economic insecurity at the household level, permitting assessment of its interactions with specific individual vulnerability profiles. The final aim is to disentangle factors informing individual\u2019s exposure to different degrees of social vulnerability, analysing their consequences and household\u2019s economic insecurity, and possible influences from the institutional context. Thanks to this project, the ER will fill her gap in quantitative research analysis and she will be able to empower her professional profile compete for tenure-track position in the international academic labour market.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["747433"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["MEDIZINISCHE UNIVERSITAT GRAZ"], "EU_Contribution": ["EUR 218 176,20"], "Project_Title": ["Image-based High-resolution In-silico Modeling of Total Cardiac Function"], "Total_Cost": ["EUR 218 176,20"], "Country": ["Austria"], "Project_ACR": ["InsiliCardio"], "Technology_Description": "Advances in medical imaging have enabled unprecedented ability to image cardiac anatomy and function. So far these technologies have had relatively modest clinical impact as the analysis of such rich multi-modal datasets has proven challenging. In silico models hold vast potential to better harness such datasets by enabling their integration into quantitative frameworks that can aid in gaining better mechanistic insight into cardiac function in health and disease, and thus paving the way towards optimal therapeutic strategies.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-03-01"], "Project_ID": ["750835"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA", "ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA"], "EU_Contribution": ["EUR 1 993 811"], "Project_Title": ["The earliest migration of Homo sapiens in Southern Europe: understanding the biocultural processes that define our uniqueness"], "Total_Cost": ["EUR 1 993 811"], "Country": ["Italy", "Italy"], "Project_ACR": ["SUCCESS"], "Technology_Description": "Anatomically modern humans (AMHs) radiated out of Africa into the rest of the world around 60,000-50,000 years ago. While various evidence suggests arrivals of AMHs in Asia and Australia ca. 45,000 calendar years before present (cal BP), the timing and pattern of the biological and cultural shifts that occurred in Europe around 50,000 to 35,000 cal BP, are hotly debated and are considered to be among the most important questions in paleoanthropology. This period documents 1) the demise of the autochthons Neandertals and their replacement by AMHs as well as 2) dramatic changes in human behaviour and the appearance of various technocomplexes that replaced pre-existing Mousterian cultures. Debate revolves around the question of whether modern behaviour was independently achieved by Neandertals or is directly related to the arrival of AMH. In this context Italy plays a pivotal role due to its geographic position and ecological variability, and key archaeological sites with transitional and early Upper Paleolithic cultures.", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["724046"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["JOHANN HEINRICH VON THUENEN-INSTITUT, BUNDESFORSCHUNGSINSTITUT FUER LAENDLICHE RAEUME, WALD UND FISCHEREI", "FONDAZIONE CENTRO EURO-MEDITERRANEO SUI CAMBIAMENTI CLIMATICI", "WEST AFRICAN SCIENCE SERVICES CENTRE ON CLIMATE CHANGE AND ADAPTED LAND USE", "International Livestock Research Institute", "INTEGRATED CARBON OBSERVATION SYSTEM EUROPEAN RESEARCH INFRASTRUCTURE CONSORTIUM", "UNIVERSITY OF THE WITWATERSRAND JOHANNESBURG", "THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN", "SOUTHERN AFRICAN SCIENCE SERVICE CENTRE FOR CLIMATE CHANGE AND ADAPTIVE LAND MANAGEMENT", "NATIONAL RESEARCH FOUNDATION", "HELMHOLTZ ZENTRUM FUR OZEANFORSCHUNG KIEL", "LEIBNIZ INSTITUT FUER TROPOSPHAERENFORSCHUNG e.V.", "UNIVERSITETET I BERGEN", "UNI RESEARCH AS", "USTAV VYZKUMU GLOBALNI ZMENY AV CR VVI", "LUNDS UNIVERSITET", "INSTITUTO NACIONAL DE DESENVOLVIMENTO DAS PESCAS"], "EU_Contribution": ["EUR 1 999 890"], "Project_Title": ["Supporting EU-African Cooperation on Research Infrastructures for Food Security and Greenhouse Gas Observations"], "Total_Cost": ["EUR 1 999 890"], "Country": ["Germany", "Italy", "Ghana", "Kenya", "Finland", "South Africa", "Ireland", "Namibia", "South Africa", "Germany", "Germany", "Norway", "Norway", "Czech Republic", "Sweden", "Cape Verde"], "Project_ACR": ["SEACRIFOG"], "Technology_Description": "African societies face growing global change risks, with rapidly changing patterns of human settlements and intensity of use of ecosystem services. At the same time, climate variability and climate change trends are intensifying stress on the ecosystems that ensure environmental security, both locally (e.g. ecosystem services), regionally (e.g. sustainable development options) and internationally (e.g. carbon sequestration). Approaches that can address this challenge in an integrated and multidisciplinary way are urgently needed in many places in Africa where there is a close relationship between societal well-being and environmental condition, relating particularly to biomass for energy and food production, and hydrological considerations such as water yields. ", "To": ["2020-02-29, ongoing project"], "Meta": [""], "Topic_s": ["INFRASUPP-01-2016 - Policy and international cooperation measures for research infrastructures"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations", "Other", "Research Organisations", "Other", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2017-03-01"], "Project_ID": ["730995"], "Call_for_Proposal": ["H2020-INFRASUPP-2016-1"]}, -{"Partners": ["ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA", "ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA", "UNIVERSITAET HAMBURG"], "EU_Contribution": ["EUR 1 465 943"], "Project_Title": ["The Magnetised Cosmic Web"], "Total_Cost": ["EUR 1 465 943"], "Country": ["Italy", "Italy", "Germany"], "Project_ACR": ["MAGCOW"], "Technology_Description": "On large scales cosmic matter is distributed in a web consistent of clusters, filaments, walls and voids.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["714196"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["PAUL SCHERRER INSTITUT", "PAUL SCHERRER INSTITUT"], "EU_Contribution": ["EUR 1 999 926"], "Project_Title": ["Hyperfine splittings in muonic atoms and laser technology"], "Total_Cost": ["EUR 1 999 926"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["HyperMu"], "Technology_Description": "The proton radius extracted from the measurements of the 2S-2P energy splitting in muonic hydrogen", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-10-01"], "Project_ID": ["725039"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON", "UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 2 159 035"], "Project_Title": ["Evolving Program Improvement Collaborators"], "Total_Cost": ["EUR 2 159 035"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["EPIC"], "Technology_Description": "EPIC will automatically construct Evolutionary Program Improvement Collaborators (called Epi-Collaborators) that suggest code changes that improve software according to multiple functional and non-functional objectives. The Epi-Collaborator suggestions will include transplantation of code from a donor system to a host, grafting of entirely new features `grown' (evolved) by the Epi-Collaborator, and identification and optimisation of tuneable `deep' parameters (that were previously unexposed and therefore unexploited).", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["741278"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA", "FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA", "QBROBOTICS SRL"], "EU_Contribution": ["EUR 149 787"], "Project_Title": ["A Soft Synergy-based Hand Prosthesis with Hybrid Control"], "Total_Cost": ["EUR 149 787"], "Country": ["Italy", "Italy", "Italy"], "Project_ACR": ["SoftHand Pro-H"], "Technology_Description": "In the project \u201cSoftHands\u201d we have achieved not only a more thorough understanding of the organization and control of hands, but also a principled approach to taming the complexity of hand design. The original concept of \u201csoft synergies\u201d has underpinned the realization of radically new artificial hands: \u201cSoftHands\u201d have been demonstrated to be more adaptive and capable than most artificial hands, yet are simpler to control and more robust. One application of these ideas and technologies which stands out for potential impact and social relevance, although not originally foreseen in the ERC AG plan, is the realization of upper limb pros-theses. The objective to realize a prosthetic hand that is anthropomorphic, aesthetically pleasing, and enables an amputee to perform most activities of daily living as well as advanced prostheses, while being robust, intuitive, and economic as basic body-powered split-hook prostheses requires a much longer and larger re-search and development effort than an ERC POC can support. In this proposal we study the feasibility of applying the SoftHand technology to address one particular, but very important, objective, i.e. work-oriented prostheses. The specific requirements of these applications are high grip power, grasp versatility, resilience, resistance to water, dust, and temperature, durability, power autonomy and low cost \u2013 while factors such as aesthetics or silent operation are less dominant. Of particular relevance is the control interface with the patient. Virtually all work-oriented prostheses are operated via a body-powered cable, which is very intuitive to use and does not need batteries, motors, and sensors. On the other hand, advanced multi-fingered prostheses have sophisticated myoelectric control affording versatility and dexterity. In this project, we will engineer and experiment a novel hybrid control for a SoftHand prosthe-sis, whereby a traditional cable harness commands the advanced mechatronic system of the SoftHand.", "To": ["2018-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Chiara Andreoli", "Tel.: +3901071781854", "Fax: +39 010 7170817", "Research Organisations", "Chiara Andreoli", "Tel.: +3901071781854", "Fax: +39 010 7170817", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["727536"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE", "INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE"], "EU_Contribution": ["EUR 2 499 994"], "Project_Title": ["INTEGRATION AND PROPAGATION OF IMMUNOLOGICAL SIGNALS DURING CANCER AND INFECTION"], "Total_Cost": ["EUR 2 499 994"], "Country": ["France", "France"], "Project_ACR": ["ENLIGHTEN"], "Technology_Description": "The immune system uses both short- and long-range communication mechanisms to mount the coordinated and sophisticated cellular responses required to control microbial infections or fight tumors. Yet, our understanding of how immunological signals are integrated and propagated by individual cells in complex tissue microenvironments remains largely limited.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["741167"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITETET I BERGEN", "UNIVERSITETET I BERGEN"], "EU_Contribution": ["EUR 1 997 918"], "Project_Title": ["Discretion and the child\u00b4s best interests in child protection"], "Total_Cost": ["EUR 1 997 918"], "Country": ["Norway", "Norway"], "Project_ACR": ["DISCRETION"], "Technology_Description": "DISCRETION aims to unlock the black box of discretionary decision-making in child protection cases by a comparative-empirical study of how discretionary decisions are made and justified in the best interests of the child. There are huge research gaps in this important area of the welfare state, with a great deal of uncertainty concerning how, when and why discretionary decisions about the child\u00b4s best interests are different between decision-makers within and between child protection systems.", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["724460"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL", "KATHOLIEKE UNIVERSITEIT LEUVEN", "UNIVERSITY OF NEWCASTLE UPON TYNE", "LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN", "UNIVERSIDADE DO PORTO", "STICHTING VU", "ACADEMISCH ZIEKENHUIS GRONINGEN", "Centre Hospitalier Regional et Universitaire de Lille", "MOTEK MEDICAL B.V.", "GAIT UP SA", "HASOMED HARD-UND SOFTWARE FUER MEDIZIN GESELLSCHAFT MBH", "PATIENTS KNOW BEST LIMITED"], "EU_Contribution": ["EUR 3 059 313,21"], "Project_Title": ["Industrial Academic Initial Training Network towards specific diagnosis and treatment of age-related gait and balance deficits"], "Total_Cost": ["EUR 3 059 313,21"], "Country": ["Germany", "Belgium", "United Kingdom", "Germany", "Portugal", "Netherlands", "Netherlands", "France", "Netherlands", "Switzerland", "Germany", "United Kingdom"], "Project_ACR": ["Keep Control"], "Technology_Description": "Balance and gait deficits are ubiquitous among the older population, and lead to enormous personal, occupational and health care burden. Emerging pharmacological and non-pharmacological interventions to date have only small to moderate effects on these deficits. This is likely due to remaining fundamental questions on underlying mechanisms and treatment. The present project Keep Control consists of a rare EU-wide combination of experts from clinical, biomechanic and neuroscience research, along with experts from the industry, who all aim at gaining a better understanding and treatment of balance and gait deficits in older adults. We aim to scrutinize aspects such as: (1) comparability of balance and gait assessment in the clinic and the home environment, (2) gait and balance deficits as prodromal markers of neurodegeneration, and as markers to differentiate between Parkinsonian syndromes, (3) association between freezing of gait and balance, and (iv) gait and balance deficits in patients with sarcopenia. Tools such as sophisticated lab-based gait and balance assessment devices, perturbation treadmill, wearable devices, electrophysiology and blood and tissue investigations will be implemented. We will further employ promising therapeutic strategies for specific gait and balance deficits in older adults, including both pharmacologic and non-pharmacologic strategies. An entire work package will be dedicated to a novel harmonization and integration approach across the whole network: It will (i) harmonize assessment protocols based on the WHO definition of health and disability, to pave the way for an exhaustive meta-analysis of all data collected, and (ii) foster the active involvement of all study participants by implementation of a participant-controlled medical record. In summary, Keep control will cover the entire range of expertise necessary and utilize cutting edge technology to educate fellows in the area of gait and balance deficits in older adults.", "To": ["2021-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-03-01"], "Project_ID": ["721577"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["HELSINGIN YLIOPISTO", "UNIVERSITEIT GENT", "POLITECHNIKA WARSZAWSKA", "VOXDALE BVBA", "UNIVERSITEIT ANTWERPEN", "Academisch Medisch Centrum bij de Universiteit van Amsterdam", "APTUIT (VERONA) SRL", "UNIVERSIDADE DO PORTO"], "EU_Contribution": ["EUR 2 265 900,12"], "Project_Title": ["Multidisciplinary European training network for development of personalized anti-infective medical devices combining printing technologies and antimicrobial functionality"], "Total_Cost": ["EUR 2 265 900,12"], "Country": ["Finland", "Belgium", "Poland", "Belgium", "Belgium", "Netherlands", "Italy", "Portugal"], "Project_ACR": ["PRINT-AID"], "Technology_Description": "According to ECDC, over 4 million healthcare-associated infections in the EU cause 37,000 deaths and cost EUR 7 billion/year. Half of them are related to medical devices (i.e., catheters, implants) and 80% of these are related to bacterial biofilms. A recent EC report highlighted the medical device sector\u2019s role in driving EU economic growth, employing 500k people in 25k companies (80% are SMEs) with annual sales of EUR 85 billion. The strategy to prevent medical device-infections is alteration of the device\u2019s surface with antimicrobials. However, current antimicrobial surfaces don\u2019t control bacterial growth in tissue surrounding implants, and only Sterilex\u00ae has received regulatory approval in the US as anti-biofilm agent. Participants in this proposal have earlier demonstrated a dramatic in vitro inhibition of biofilm formation by 3D-printing surfaces with antibiotics incorporated into the carrier polymers. This discovery opens new possibilities for printed medical devices that better resist biofilms. Our objective is to set-up a new European education platform to guide and inspire young researchers in the intersectoral exploration of innovative routes to counteract microbial biofilms by fabricating anti-infective, tailored, 3D-printed medical devices. Current opportunities for young researchers to receive an structured, inter-sectoral and up-to-date education on personalized medicine and medical devices are marginal, and to our knowledge PRINT-AID is the first ETN set up for this purpose. State-of-the-art printing technologies will be combined with in vitro and in vivo biofilm models and novel tools for data integration/standardization. Doctoral training will be performed within a high-quality network of 12 participants (5 industrial) from the EU and US. It will include online and face-to-face courses taught by researchers with academic and industrial expertise in biofilms, 3D-printing research, antimicrobials, material science, and drug development.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["722467"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["TECHNISCHE UNIVERSITAET WIEN", "TECHNISCHE UNIVERSITAET WIEN", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 460 826"], "Project_Title": ["Towards chemical accuracy in computational materials science"], "Total_Cost": ["EUR 1 460 826"], "Country": ["Austria", "Austria", "Germany"], "Project_ACR": ["CC4SOL"], "Technology_Description": "This project aims at the development of a novel toolbox of ab-initio methods that approximate the true many-electron wavefunction using systematically improvable perturbation and coupled-cluster theories. The demand and prospects for these methods are excellent given that the highly-accurate coupled-cluster theories can predict atomization- and reaction energies in a wide range of solids and molecules with chemical accuracy (\u224843 meV). However, the computational cost involved inhibits their widespread use in the field of materials science so far. A multitude of suggested developments in the present proposal hold the promise to reduce the computational cost beyond what is currently considered possible by the community. These include explicit correlation methods that augment the conventional wavefunction expansion with terms that depend on the electron pair correlation factors. In contrast to the widely-used homogeneous correlation factors, this proposal aims at the investigation of inhomogeneous correlation factors that can also capture van der Waals interactions. Furthermore this proposal seeks to employ a recently developed combination of atom-centered basis functions and plane wave basis sets, maximizing the compactness in the wavefunction expansion. The combination of these ideas bears the potential to reduce the computational cost of coupled-cluster calculations in solids by three orders of magnitude, leading to a breakthrough in the field of highly-accurate ab-initio simulations. As such the study of challenging solid state physics and chemistry problems forms an important part of this proposal. We seek to investigate molecular adsorption and reactions in zeolites and on surfaces, pressure-driven solid-solid phase transitions of two dimensional layered materials and defects in solids. These problems are paradigmatic for van der Waals interactions and strong correlation, and methods that describe their electronic structure accurately are highly sought after.", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-07-01"], "Project_ID": ["715594"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["LANCASTER UNIVERSITY", "KUNGLIGA TEKNISKA HOEGSKOLAN", "THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "UNIVERSITA DI PISA", "UNIVERSITAT JAUME I DE CASTELLON", "UNIVERSITA CATTOLICA DEL SACRO CUORE", "BOGAZICI UNIVERSITESI", "PHILIPS ELECTRONICS NEDERLAND B.V.", "THE LEEDS TEACHING HOSPITALS NATIONAL HEALTH SERVICE TRUST", "PLUX - WIRELESS BIOSIGNALS S.A."], "EU_Contribution": ["EUR 3 888 273,60"], "Project_Title": ["Personal Technologies for Affective Health"], "Total_Cost": ["EUR 3 888 273,60"], "Country": ["United Kingdom", "Sweden", "Ireland", "United Kingdom", "Italy", "Spain", "Italy", "Turkey", "Netherlands", "United Kingdom", "Portugal"], "Project_ACR": ["AffecTech"], "Technology_Description": "Personalized health is a European priority and one of the strategic research areas for Horizon 2020. This project advances the state-of-the-art of personal health technologies for affective disorders, estimated to be the highest ranking cause of disease by 2020. It marks a significant shift from the current wearable technologies capturing emotional responses whose understanding usually requires physicians\u2019 input, to low-cost self-help technologies for visualizing, exploring and regulating emotions. ", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["722022"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["UNIVERSITAT ZURICH"], "EU_Contribution": ["EUR 187 419,60"], "Project_Title": ["Embodied Cognitive Neuromorphic Technology"], "Total_Cost": ["EUR 187 419,60"], "Country": ["Switzerland"], "Project_ACR": ["ECogNeT"], "Technology_Description": "Biological neuronal networks allow humans and animals to build representations of objects, complex scenes, and temporal sequences and to use these representations to plan and execute goal-directed actions, learn new skills, and constantly adapt to changing situations. Neuronal systems have evolved to be extremely powerful in perceiving and acting in complex and dynamic real-world environments. The field of neuromorphic engineering is realising neuronal computation in a new generation of hardware systems, aiming to enable computation with high efficiency and low energy cost, comparable to biological neuronal networks. In order to use this hardware to implement systems that can solve perceptual, motor, and cognitive tasks, cognitive architectures have to be developed, which integrate elementary cognitive processes in a coherent computational framework. The ECogNeT project aims to develop such a computational framework by realising neural-dynamic models of embodied cognition in neuromorphic hardware. In particular, the computational and conceptual framework of Dynamic Neural Fields will be used to create cognitive computational primitives in neuromorphic hardware, which will organise the hardware neurons in attractor-networks, capable to generate discrete, cognitive representations from sensory inputs. The developed neuromorphic cognitive architecture will be integrated with sensors and motors of a robotic agent and its capability to represent environmental situations and temporal sequences of events will be validated in benchmark scenarios, exploiting the potential of this new technology in development of novel, low-power, fast, and smart devices capable to work in real-world settings in order to advance future prosthetic systems, smart environments, and assistive robots.", "To": ["2018-03-31, Grant Agreement terminated |"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-04-01"], "Project_ID": ["707373"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["KATHOLIEKE UNIVERSITEIT LEUVEN"], "EU_Contribution": ["EUR 172 800"], "Project_Title": ["Public Administration and Technology"], "Total_Cost": ["EUR 172 800"], "Country": ["Belgium"], "Project_ACR": ["PATECH"], "Technology_Description": "Digital technologies are in the centre of the ongoing industrial revolution that is bound to change not only markets, but also societies and governments. Central to these developments is the evolution of public sector technological capacities, that is, an ability of public organizations to explore, develop and/or adapt new technological solutions in public service design, delivery and evaluation. One of the central questions that has so far fallen in between different research strands is how technology affects the evolution of work organization and administrative capacities in public sector. In the context of increasing dependence on technological developments, and thus, related opportunities as well as uncertainties and risks, the conventional public administration accounts fall short in fully grasping the influence of technology on public sector change. The research objectives of the project are to: a) develop a coherent and novel conceptual framework on public sector technological capacities and provide novel and empirically grounded explanations on the co-evolutionary development mechanisms of public organizations and technology through comparative cross-country analysis. In order to map and understand different co-evolutionary patterns, the project will use a comparative approach by studying two different fields (with high and low/moderate level of technological complexity) in two different small states (in an advanced (Belgium) and less advanced (Estonia) socio-economic contexts).", "To": ["2019-05-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-29"], "Project_ID": ["750378"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FONDAZIONE IRCCS ISTITUTO NEUROLOGICO CARLO BESTA", "UNIVERSITEIT MAASTRICHT", "FONDAZIONE IRCCS ISTITUTO NAZIONALE DEI TUMORI", "OSPEDALE SAN RAFFAELE SRL", "YALE UNIVERSITY", "NEUROSCIENCE TECHNOLOGIES SLP", "NsGene A/S", "DI.V.A.L. TOSCANA SRL", "CENTRE EUROPEEN DE RECHERCHE EN BIOLOGIE ET MEDECINE", "ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA"], "EU_Contribution": ["EUR 3 354 464,57"], "Project_Title": ["Molecule-to-man pain network"], "Total_Cost": ["EUR 3 354 464,57"], "Country": ["Italy", "Netherlands", "Italy", "Italy", "United States", "Spain", "Denmark", "Italy", "France", "Italy"], "Project_ACR": ["PAIN-Net"], "Technology_Description": "Neuropathic pain affects 5% of the general population and 40% of patients with neurological diseases, and has a key role in the pathophysiology of cancer pain that affects up to 50% of patients in the early disease stage and 30% of survivors, causing an enormous social burden. Treatments are inadequate with less than 50% of patients achieving 50% of pain relief at best, while up to 30% of cancer pain patients experience insufficient analgesia. Signatures of individual susceptibility to pain and analgesic responsiveness are urgently needed to improve patients\u2019 management. Such advances are expected to originate from integrated clinical, basic science and entrepreneurial research readily translating scientific findings into benefits for patients. To consolidate these aims, a new generation of scientists with wide knowledge in neuropathic pain, focused research skills and experience in the interaction with biotechnology companies is needed. The PAIN-Net programme, based on a highly innovative platform of training-through-research and strongly committed to such objectives, will support such talented and inspired early stage researchers. Their research projects, embedded in an advanced molecule-to-man pain network, will contribute to better understanding individual susceptibility to pain and analgesics responsiveness based on next generation sequencing, whole exome sequencing, epigenetics and pharmacogenomics studies, nociceptor and sodium channel functioning based on biophysics and proteomics studies, targeted analgesics based on high-throughput screening, targeted analgesic delivery based on encapsulated cell bioreactor implants, and to the development and extensive characterisation of the first knock-in mouse models of sodium channel-related neuropathic pain based on the CRISP-Cas technology. Most of all, the PAIN-Net programme will offer the unique opportunity to enhance scientific capabilities and prepare to high level academic or private applied research career.", "To": ["2021-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2017-02-01"], "Project_ID": ["721841"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["FUNDACION PRIVADA INSTITUTO DE SALUD GLOBAL BARCELONA"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Unraveling the protein glycosylation of Plasmodium falciparum is crucial for development of novel therapeutics against malaria"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["SugarBlock"], "Technology_Description": "Annually, malaria causes 200 million clinical cases and more than half a million deaths. Works carried out more than 40 years ago demonstrated that a malaria vaccine offering sterile protective immunity in humans was possible, but the efforts to develop a modern, recombinant \u2018subunit\u2019 malaria vaccine only confer short term protection against clinical malaria in 35-50% of recipients. Several evidences support the presence of foreign short N-glycans and other minor glycosylations in the surfaces of the parasite, Plasmodium faciparum, the causative agent of malaria. In addition, recent studies show that Plasmodium sporozoites present also unknown \u03b1-galactose containing antigens in their surface and that antibodies against them provide sterile protection against malaria in mice. We propose to completely characterize the protein glycosylation present in the surface of the extracellular sporozoites, that travel from the mosquito to the liver, and merozoites, that invade human erythrocytes. We will use different quasi-targeted glycoproteomic approaches, based on the expected simplicity and low variability of these glycosylations in the parasite surface and their affinity to well characterized lectins. The investigation of these uncommon parasitic glycosylations may expose an unexpected Achilles\u2019 heel in the Plasmodium parasite that could be exploited to halt sporozoite development and/or stop merozoite invasion and induce protection against malaria, mimicking what has already been achieved using carbohydrate-protein conjugate vaccines against bacterial infections.", "To": ["2018-08-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2016-08-29"], "Project_ID": ["703305"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["TECHNISCHE UNIVERSITAET DRESDEN", "TECHNISCHE UNIVERSITAET DRESDEN"], "EU_Contribution": ["EUR 2 500 000"], "Project_Title": ["Chiral Morphogenesis - Physical Mechanisms of Actomyosin-Based Left/Right Symmetry Breaking in Biological Systems"], "Total_Cost": ["EUR 2 500 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["CHIMO"], "Technology_Description": "The aim of this grant is to understand how cellular, tissue-scale and organismal left-right asymmetry arises from the chirality of molecular constituents. In many instances the actomyosin cortex, a thin and mechanically active layer of dynamically cross-linked filaments and molecular motors at the surface of cells, drives the emergence of chiral morphogenetic events. In the nematode Caenorhabditis elegans, mesoscale chiral active torques generated by this active layer establish the embryo\u2019s left-right body axis. Here we want to understand how mesoscale actomyosin active torques are generated at the molecular level, and how active torque generation in the actomyosin surface drives chiral morphogenesis of cells, tissues and organisms. Cells and tissues represent a new class of active chiral materials where both the force and the torque balance need to be considered, and we will perform a systematic and cross-scale characterization of active chiral biological matter. We will pursue an interdisciplinary approach at the interface of physics and biology. At the molecular-scale, we will use optical tweezers to measure active torques generated by single molecules of the molecular myosin and the actin polymerizing protein formin. At the cell-scale, we will reconstitute chiral actomyosin flows in vitro and characterize chiral dynamics of single molecules in vivo. At the tissue-scale, we will investigate chiral cell movements in a multicellular environment and unravel the physical basis of chiral tissue flow in vertebrates. Theory is essential at all stages, and we will build a molecular-scale model of actomyosin torque generation that will be coarse-grained to a generalized hydrodynamic description of active chiral matter. This interdisciplinary and cross-scale approach will provide fundamentally new insights into active chiral materials and the mechanisms by which left-right asymmetries arise in development.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["742712"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA", "CARDIFF UNIVERSITY", "CONSIGLIO NAZIONALE DELLE RICERCHE", "ELVESYS SAS", "TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY", "FUNDACIO PRIVADA INSTITUT CATALA D'INVESTIGACIO QUIMICA", "CHIROTECH TECHNOLOGY LIMITED", "UNIVERSITA DEGLI STUDI DI TRIESTE", "KATHOLIEKE UNIVERSITEIT LEUVEN"], "EU_Contribution": ["EUR 3 630 212,28"], "Project_Title": ["ENTREPRENEURING DYNAMIC SELF-ORGANIZED INTERFACES IN PHOTOCATALYSIS: A MULTIDISCIPLINARY TRAINING NETWORK CONVERTING LIGHT INTO PRODUCTS"], "Total_Cost": ["EUR 3 630 212,28"], "Country": ["Italy", "United Kingdom", "Italy", "France", "Israel", "Spain", "United Kingdom", "Italy", "Belgium"], "Project_ACR": ["PHOTOTRAIN"], "Technology_Description": "The global need to move current human technologies into a sustainable future will have a great impact for the world of chemistry and related industries. In close concert with other disciplines, chemistry will be increasingly solicited to identify solutions that are practical, affordable and ultimately sustainable. To meet these objectives, not only research, but also chemical education will need profound reforms that have to be contextualized in the multidisciplinary and intersectoral picture of a sustainable development. It is propelled by these societal needs that, by educating and practising 14 ESRs, PHOTOTRAIN will ensure photo-triggered chemical process to play its central role in sustainability. By capitalising on the basic principles of supramolecular chemistry to program dynamic self-organized photoactive interfaces, it is intended to raise the creativity, knowledge, skills and capacity of the ESRs to conceive new ideas for reforming current industrial transformations into a new generation of \u201clight-triggered\u201d processes. The challenge of developing and transferring light-fuelled processes from a proof-of-principle to an exploitable process is to embark upon a dynamic configuration in which photoactive species are kept separated, act independently and are finally recycled. In particular, through the adoption of a microfluidic system in which programmed different phases allow the formation of photoactive interfaces, it is planned to implement photo-catalytic technologies at the industrial level for triggering stereoselective organocatalytic transformations (i.e., pharmaceutical applications) and/or solar fuels production. By the organisation of targeted individual projects and interdisciplinary secondements, ESRs will be guided toward attractive early-stage career opportunities as researchers, process chemists, chemical engineers and research managers in collective forms at various academic and research institutes, small and large enterprises, and NGOs.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["722591"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["EUROPEAN UNIVERSITY INSTITUTE", "EUROPEAN UNIVERSITY INSTITUTE"], "EU_Contribution": ["EUR 829 000"], "Project_Title": ["Oligopoly Markets and Networks"], "Total_Cost": ["EUR 829 000"], "Country": ["Italy", "Italy"], "Project_ACR": ["Connections"], "Technology_Description": "Via our connections we learn about new ideas, quality of products, new investment opportunities and job opportunities. We influence and are influenced by our circle of friends. Firms are interconnected in complex processes of production and distribution. A firm\u2019s decisions in a supply chain depends on other firms\u2019 choices in the same supply chain, as well as on firms' behaviour in competing chains. Research on networks in the last 20 years has provided a series of tolls to study a system of interconnected economic agents. This project will advance the state of the art by further developing new applications of networks to better understand modern oligopoly markets. ", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["724356"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSIDADE DE LISBOA", "UNIVERSIDADE DO PORTO", "UNIVERSIDADE DO MINHO", "NOVA ID FCT - ASSOCIACAO PARA A INOVACAO E DESENVOLVIMENTO DA FCT", "INSTITUTO UNIVERSITARIO DE LISBOA", "CAMARA MUNICIPAL DE LISBOA"], "EU_Contribution": ["EUR 159 750"], "Project_Title": ["Science in everyday life"], "Total_Cost": ["EUR 159 750"], "Country": ["Portugal", "Portugal", "Portugal", "Portugal", "Portugal", "Portugal"], "Project_ACR": ["SCILIFE"], "Technology_Description": "SCILIFE \u2013 Science in Everyday Life \u2013 is a European Researchers\u2019 Night (ERN) proposal. It builds on previous experience of successful editions to bring ERN\u2019s aims to a different level in the Portuguese context. Using the theme of Science in Everyday Life as a point of departure, SCILIFE will address \u2018traditional\u2019 science and society issues \u2013 e.g. citizens\u2019 engagement with sustainable and inclusive research, scientific careers, society\u2019s involvement in science policy, decision-making and collective deliberation \u2013 but it will do so by bringing Responsible Research and Innovation (RRI) strategically into the public debate. ", "To": ["2017-11-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-NIGHT-2016 - European Researchers' Night"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Portugal"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2016-05-01"], "Project_ID": ["723006"], "Call_for_Proposal": ["H2020-MSCA-NIGHT-2016"]}, -{"Partners": ["ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA", "UNIVERSITE CATHOLIQUE DE LOUVAIN", "OROBOROS INSTRUMENTS GmbH", "JUSTUS-LIEBIG-UNIVERSITAET GIESSEN", "GEMEINNUTZIGE SALZBURGER LANDESKLINIKEN BETRIEBSGESELLSCHAFT", "KAROLINSKA INSTITUTET", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "BIOCRATES LIFE SCIENCES AG", "AvantiCell Science Ltd", "UNIVERSITE DE BORDEAUX"], "EU_Contribution": ["EUR 2 856 812,04"], "Project_Title": ["TRANSlating the role of Mitochondria in Tumorigenesis"], "Total_Cost": ["EUR 2 856 812,04"], "Country": ["Italy", "Belgium", "Austria", "Germany", "Austria", "Sweden", "United Kingdom", "Austria", "United Kingdom", "France"], "Project_ACR": ["TRANSMIT"], "Technology_Description": "The consolidation of the knowledge that cancer is not only a genetic, but also a metabolic disease, has led scientists to investigate the intricate metabolic plasticity that transformed cells must undergo to survive the adverse tumor microenvironment conditions, and the contribution of oncogenes and tumor suppressors in shaping metabolism. In this scenario, genetic, biochemical and clinical evidences place mitochondria as key actors in cancer metabolic restructuring, not only because these organelles have a crucial role in the energy and biosynthetic intermediates production but also because occurrence of mutations in metabolic enzymes encoded by both nuclear and mitochondrial DNA has been associated to different types of cancer. TRANSMIT aims to dissect the metabolic remodeling in human cancers, placing the focus on the role of mitochondria and bridging basic research to the improvement/development of therapeutic strategies. Further, TRANSMIT fosters the communication of this emerging field to the patients and their families. To these aims, TRANSMIT will create a network of seven different countries, among which world-leading basic science and clinical centers of excellence, several industrial partners with up-to-date omics technologies, as well as non-profit foundations and associations who care for cancer patients. By creating the critical mass of scientific excellence, TRANSMIT will allow to transfer the current knowledge into the wide field of cancer research, translating scientific and technical advances into the education and training of eleven Early Stage Researchers. TRANSMIT will implement training-through-research dedicated to unravel the metabolic features of cancer, as well as to provide a full portfolio of complementary skills through the creation of a network of basic, translational and industrial laboratories, devoted to a multidisciplinary/multisectorial education of young scientists.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["722605"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["UNIVERSITY OF STRATHCLYDE", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "ZILINSKA UNIVERZITA V ZILINE", "UNIVERZITET U NOVOM SADU FAKULTET TEHNICKIH NAUKA", "SCHEIDT & BACHMANN SLOVENSKO S.R.O.", "RAMBOLL UK LIMITED", "PANONIT DOO ZA SISTEME ZASNOVANE NA RACUNARU RAZVOJ I PROIZVODNJU U OBLASTI INFORMACIONIH TEHNOLOGIJA"], "EU_Contribution": ["EUR 832 500"], "Project_Title": ["SENSors and Intelligence in BuLt Environment"], "Total_Cost": ["EUR 859 500"], "Country": ["United Kingdom", "Spain", "Slovakia", "Serbia", "Slovakia", "United Kingdom", "Serbia"], "Project_ACR": ["SENSIBLE"], "Technology_Description": "The goal of this project is to develop novel information sensing research and innovation approaches for acquiring, communicating and processing a large volume of heterogeneous datasets in the context of smart buildings, by building an international, inter-disciplinary and inter-sectoral collaboration network through research and innovation staff exchanges and seamless exchange of ideas, expertise, data, testbeds, and know-how. ", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["734331"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE UNIVERSITY OF WARWICK", "LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE"], "EU_Contribution": ["EUR 1 983 400"], "Project_Title": ["Productivity and Development: The Ready-made Garment Productivity Project"], "Total_Cost": ["EUR 1 983 402,25"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom", "United Kingdom"], "Project_ACR": ["RMGPP"], "Technology_Description": "Differences in productivity explain much of differences in income levels across countries, yet little is known about how to improve productivity of manufacturing in the developing world. Recent research reveals very high dispersion in productivity in low-income countries. We examine firm productivity at a uniquely detailed level, collecting sub-factory production and survey data from hundreds of garment manufacturers in several countries. The data, coupled with a new method for comparing productivity, allow us to measure physical productivity in and across firms and among heterogeneous products. Initial results from nearly 100 factories in Bangladesh show significant dispersion of productivity within factories; production lines at the 90th percentile are 50% more efficient than those at the 10th percentile. Differences are highly persistent \u2013 puzzling given that the lines are often on the same production floor. Capital and the quality of the buyer explains a small part of the dispersion: lines producing goods for higher-end buyers are significantly more efficient.", "To": ["2020-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-12-01"], "Project_ID": ["669746"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["EBERHARD KARLS UNIVERSITAET TUEBINGEN"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Gen Duplication and Amplification in Staphylococcal populations"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["GDA in staphylococci"], "Technology_Description": "Bacterial pathogens possess the ability to adapt rapidly to changing environmental conditions which is especially apparent in the hospital setting where bacteria acquire antibiotic resistances readily. Besides well studied mechanisms such as horizontal gene transfer bacteria can alter the genetic material by acquiring gen duplications and amplifications (GDA). Exemplarily an improved gene dosage of a minor resistance determinant can lead to increased resistance to antibiotics. Due to the difficulties in their detection GDAs are almost exclusively studied in model organisms and neglected in natural populations of clinically relevant species such as Staphylococcus aureus. Accordingly many important questions about the frequency and clinical importance of GDAs remain unanswered. State of the art sequencing technologies enable the identification of GDAs by analysis of the coverage scaffold and groundbreaking experiments using 387 USA300 genome sequences showed promising results regarding putative copy number variation of virulence factors. We will extend the GDA analysis to ca. 1200 already available EMRSA15 sequences. This will enable a comprising analysis of gen copy number variation in clinical isolates and might allow identifying genomic regions under strong evolutionary pressure during infection. We will optimize experimental setups for the rapid validation of GDAs by qPCR and develop techniques to study the effects of GDAs in S. aureus. Furthermore we will sequence a selection ca. 70 S. aureus isolates causing chronic infections in patients suffering from cystic fibrosis (CF). This will enable us to optimize the detection of GDAs by NGS and will allow investigating the role of GDAs during adaption to the complex environment within the CF-lung. This project will show new avenues to extract additional valuable biological information from NGS data and will investigate the importance of GDAs during the adaption of S. aureus to the hospital setting and to the CF-lung.", "To": ["2017-12-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["655978"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["AALTO-KORKEAKOULUSAATIO"], "EU_Contribution": ["EUR 267 793,20"], "Project_Title": ["Advanced Wide-Band Transceiver Architectures for Beyond 5G Wireless Systems"], "Total_Cost": ["EUR 267 793,20"], "Country": ["Finland"], "Project_ACR": ["ADVANTAG5"], "Technology_Description": "The fifth generation and beyond radio systems targets 1000 times traffic volumes compared to present state-of-the-art. In order to guarantee the quality of service, communication capacity leap of three orders of magnitude requires sophisticated interference management and communication channel protection from the interference generated by other users. The objective of this project is to develop integrated transceiver hardware structures for massive MIMO/beam forming antenna arrays, supporting agile carrier aggregation, digitally assisted interference management, and full duplex communication, thus enhancing communication efficiency in spatial, temporal and frequency domains. ", "To": ["2020-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["704947"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["LIVERPOOL JOHN MOORES UNIVERSITY"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["The cardiovascular consequences of endurance exercise"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["CARDI-ACHE"], "Technology_Description": "Problem: Exercise training represents an attractive and low-cost strategy to improve cardiovascular health. Recent studies, however, report novel evidence that endurance exercise can lead to potentially detrimental cardiac maladaptations. First, acute exercise-induced elevations in cardiac troponin (cTn) levels have been found, which typically reflect myocardial (micro-)damage and are predictive of future cardiovascular events and mortality. Secondly, myocardial fibrosis has been reported in 12\u201350% of individuals engaged in lifelong exercise training, reflecting scarring of cardiac tissue that is typically found in patients with cardiovascular diseases (CVD). These cardiac maladaptations are highly unexpected and largely unexplained in apparently healthy individuals.", "To": ["2017-05-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-06-01"], "Project_ID": ["655502"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["BIOMEDICAL SCIENCES RESEARCH CENTER ALEXANDER FLEMING", "BIOMEDICAL SCIENCES RESEARCH CENTER ALEXANDER FLEMING"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["A genomics and systems biology approach to explore the molecular signature and functional consequences of long-term, structured fasting in humans"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Greece", "Greece"], "Project_ACR": ["FastBio"], "Technology_Description": "Dietary intake has an enormous impact on aspects of human health, yet scientific consensus about how what we eat affects our biology remains elusive. To address the complex biological impact of diet, I propose to apply an unconventional, \u2018humans-as-model-organisms\u2019 approach to compare the molecular and functional effects of a highly structured dietary regime, specified by the Eastern Orthodox Christian Church (EOCC), to the unstructured diet followed by the general population. Individuals who follow the EOCC regime abstain from meat, dairy products and eggs for 180-200 days annually, in a temporally-structured manner initiated in childhood. I aim to explore the biological signatures of structured vs. unstructured diet by addressing three objectives. First I will investigate the effects of the two regimes, and of genetic variation, on higher-level phenotypes including anthropometric, physiological and biomarker traits. Second, I will carry out a comprehensive set of omics assays (metabolomics, transcriptomics, epigenomics and investigation of the gut microbiome), will associate omics phenotypes with genetic variation, and will integrate data across biological levels to uncover complex molecular signatures. Third, I will interrogate the functional consequences of dietary regimes at the cellular level through primary cell culture. Acute and long-term effects of dietary intake will be explored for all objectives through a two timepoint sampling strategy. This proposal therefore comprises a unique opportunity to study a specific perturbation (EOCC structured diet) introduced to a steady-state system (unstructured diet followed by the general population) in a ground-breaking human systems biology type of study. This approach brings together expertise from genomics, computational biology, statistics, medicine and epidemiology. It will lead to novel insights regarding the potent signalling nature of nutrients and is likely to yield results of high translational value.", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Greece"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-06-01"], "Project_ID": ["716998"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["GOETEBORGS UNIVERSITET"], "EU_Contribution": ["EUR 173 857,20"], "Project_Title": ["Photocaged Kinase Inhibitors as Molecular Tools for Investigating Neurodegenerative Diseases"], "Total_Cost": ["EUR 173 857,20"], "Country": ["Sweden"], "Project_ACR": ["PCAGED-KI"], "Technology_Description": "Protein kinases play a critical role in a number of cellular processes, including cell proliferation, differentiation and apoptosis. Recently, the aberrant regulation of lymphocyte-specific protein tyrosine kinases (LCK) has been associated with the over activation of microglia cells (important immune effector cells that reside in the central nervous system, CNS) and in turn, the development of Alzheimer\u2019s disease (AD). Unfortunately, the detail of LCK's dynamic function and the importance of quantitative, spatial and time-dependent parameters regarding microglia activation is poorly understood. As such, the ability to manipulate LCK activity using light would result in temporal control of enzymatic activity, thus serving as a valuable approach to probe the function of LCK in microglia cells and in turn, further our understanding of AD and related neurodegenerative disorders. While such studies cannot be performed using conventional LCK inhibitors, this project aims to control the enzymatic activity of LCK by the development of a stimuli-responsive release-and-report system, through the introduction of a photolabile 'caging' moiety onto a fluorescent kinase inhibitor. The caging group will also consist of an appropriate \u2018quencher\u2019, quenching the innate fluorescence properties of the inhibitor through energy transfer (FRET). Exposure to light (> 320 nm) will result in decaging of the prodrug to give the active form, while simultaneously switching \u2018on\u2019 the fluorescence \u2014 reporting back to the user that the compound has been activated. To demonstrate the potential of the release-and-report kinase inhibitor as a tool to probe LCK function in microglia cells, confocal microscopy will be employed to visualise the site of microglia activation and the time frame during CNS development in zebrafish model systems.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["745626"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KING'S COLLEGE LONDON"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Strategic U-Turns between the EU and Russia: Explanatory Prospects of Prospect Theory"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["EUEaPRU"], "Technology_Description": "\"The project attempts to test the potential of prospect theory in explaining the strategic choices of countries located in the common neighbourhood between the European Union (EU) and Russia. Under what conditions ruling elites in Eastern Partnership (EaP) countries select EU or Eurasian Economic Union (EaEU) as integration projects? The theoretical expectation is that different values of gains and losses, judged against a given \"\"reference point\"\", are associated with one or another integration project and may be at work in the selection of strategic choices of EaP countries. Prospect theory, a Nobel Prize-winning theoretical construct, has roots in cognitive psychology, but it has uncovered its extraordinary potential to explain decisions under conditions of uncertainly and risk in behavioural economics. The attempts of importing the insights of prospect theory into political science are slowly growing, but there is yet a long way ahead until political science will fully integrate them into its ontological agenda. The proposed project is going to be a pioneering application of prospect theory to the strategic alternatives faced by countries located in the common neighbourhood between the EU and Russia.\"", "To": ["2020-02-29, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["746909"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ANGLIA RUSKIN UNIVERSITY HIGHER EDUCATION CORPORATION"], "EU_Contribution": ["EUR 97 727,40"], "Project_Title": ["Shaping a Preferable Future: Children Reading, Thinking and Talking aboutAlternative Communities and Times"], "Total_Cost": ["EUR 97 727,40"], "Country": ["United Kingdom"], "Project_ACR": ["ChildAct16"], "Technology_Description": "Despite overall agreement that children\u2019s voices matter in the development of policies affecting them, little effort has been made to develop cultural practices encouraging utopianism as a critical attitude to reality and a means of facilitating the expression of formative opinions on the part of children. Nor have young readers\u2019 interpretations of utopian literature been investigated as indicating their perception of the sociopolitical arrangements around them, including the context of the EU.", "To": ["2018-08-20, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-21"], "Project_ID": ["745888"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["EUROPEAN UNIVERSITY INSTITUTE"], "EU_Contribution": ["EUR 168 277,20"], "Project_Title": ["Western Strategies in East Asia. The Reconfiguration of US, British and French security policies in the Pacific Century"], "Total_Cost": ["EUR 168 277,20"], "Country": ["Italy"], "Project_ACR": ["WESTRAT"], "Technology_Description": "The core question that this project tackles is how the three major Western military powers (the US, Britain and France) have adapted their security policies to the shifting center of strategic gravity of international politics from the Euro-Atlantic area to the Asia-Pacific. In addressing this question, WESTRAT conducts a comparative analysis of their evolving security policies in confronting the main \u201ctraditional\u201d and \u201cnon-traditional\u201d security challenges in East Asia, i.e. the rise of China, the proliferation of weapons of mass destruction and piracy. In so doing, this project makes three original contributions. (1) Firstly, WESTRAT offers an empirical contribution as the first work to provide a cross-national comparison of the security policies of the three major Western powers (1990-2016) \u2013 in their national, bilateral, and multilateral configurations \u2013 in what is deemed to be the world\u2019s new center of strategic gravity. It therefore investigates a crucial yet under-explored dimension of contemporary international politics. (2) Secondly, it provides an innovative conceptual framework that sheds light on the emerging networks of national, bilateral and multilateral security arrangements (what we label \u201cnetworked security postures\u201d) in international politics. It thereby contributes to the debates on the under-theorized relationships between bilateralism and multilateralism as venues for security cooperation. (3) Finally, given the absence of a common European strategy toward the region, this project seeks to enrich the policy discussions in the European Union (EU) and to provide policy recommendations on how to bolster cooperation between the EU, its member states, and the US \u2013 and transatlantic relations more generally \u2013 in developing a common strategy towards the (re)emergence of East Asia in world politics. Combining concepts and methods derived from international relations, from sociology, and from history, WESTRAT takes an interdisciplinary perspective.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["752790"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 149 159"], "Project_Title": ["CAPITA: Child Abuse Prevention International Training and Access"], "Total_Cost": ["EUR 149 159"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["CAPITA"], "Technology_Description": "This Proof of Concept proposal is a rare opportunity to translate social program innovation into international impact. Every year, a billion children worldwide are victims of child abuse. The highest rates are in low-and-middle-income countries, affecting children of all ages (WHO, 2012). A small number of child abuse prevention programs for young children have been tested in high-income countries and commercialized. This makes them inaccessible to the vast majority of families at risk of abuse in the developing world.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["737476"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["GOLDSMITHS' COLLEGE", "GOLDSMITHS' COLLEGE"], "EU_Contribution": ["EUR 149 995"], "Project_Title": ["Transforming Gender Justice for Conflict-Related Sexual Violence: The Gender Justice Prototype Framework for Analysis and Action"], "Total_Cost": ["EUR 149 995"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["TRANSFORM"], "Technology_Description": "How to provide justice for conflict-related sexual violence (CRSV) has now become a highly visible and challenging global problem with few solutions. The TRANSFORM project addresses this problem by creating a prototype Gender Justice Framework to guide analysis of, and responses to, conflict-related sexual violence. The ERC Gender of Justice Project (GoJ) provides a unique array of justice indicators and innovative methods that can deliver ground-breaking strategies to combat impunity for conflict-related sexual violence. The prototype Framework exploits these cutting edge analytics and insights by building them into an integrated package of guiding principles and tools for policy-makers and practitioners. These \u2018how to\u2019 guides and instruments map patterns of sexual violence and affected groups, assess the adequacy of criminal and social justice responses, and generate new justice strategies. This prototype framework for analysis and action in this difficult field has wide application for those working in the human rights, international criminal law, transitional justice, and peace building and security sectors in conflict-affected contexts.", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["737515"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["UNIVERSITA CA' FOSCARI VENEZIA"], "EU_Contribution": ["EUR 229 761"], "Project_Title": ["Atlas of Renaissance Antiquarianism"], "Total_Cost": ["EUR 229 761"], "Country": ["Italy"], "Project_ACR": ["ATRA"], "Technology_Description": "ATRA - Atlas of Renaissance Antiquarianism is a digital system that will map the circulation of antiquarian learning in sixteenth-century Europe. Its purpose is to contribute to the promotion of new knowledge on antiquarian studies in the Renaissance and demonstrate how the antiquarian approach \u2013 that based the growth of thought on documented sources and empirical evidence \u2013 played a primary role in the evolution of the entire cultural/intellectual life of Early Modern times. The main intent is to allow the interconnection of data that otherwise would probably never come into contact and to bring to the surface issues not yet bridled in rigid classifications. This will enable the discovery of new cultural itineraries and convergences in Renaissance scholarship; trace the paths that led to parallel or independent ideas; and uncover new trends of thought that can help us better understand the evolution of European civilization and spirit. ", "To": ["2020-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["745704"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["STICHTING KATHOLIEKE UNIVERSITEIT", "STICHTING KATHOLIEKE UNIVERSITEIT"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["The cell surface tetraspanin web drives tumour development and alters metabolic signalling"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["Secret Surface"], "Technology_Description": "Cancer development is characterized by uncontrolled proliferation, cell survival and metabolic reprogramming. Tumour cells are surrounded by a fluid-mosaic membrane that contains tetraspanins (Tspans) which are evolutionary conserved proteins important in the formation of multiprotein complexes at the cell surface (\u2018tetraspanin web\u2019). Increasing evidence indicates that Tspans are involved in cancer, still the architecture of the Tspan web in native tumour membranes and its (patho)physiological functions have not been resolved. Based on my preliminary data, I hypothesize that tumour cells contain a disrupted Tspan web in which Tspan interactions are modified leading to aberrant metabolic signalling and tumour development. This is supported by my discovery that loss of Tspan CD37 leads to spontaneous lymphomagenesis due to activation of the Akt survival pathway. The overall aim of Secret Surface is to unravel the composition, physiological functions and molecular mechanisms of the Tspan web on tumour development and clinical outcome. To achieve this, I will focus on studying lymphomas using a multidisciplinary approach: I. Detailed analyses of Tspan web composition in lymphoma to select clinically relevant Tspans (high-throughput tissue microarray technology, multispectral imaging). II. Resolve the endogenous Tspan web on lymphoma cells (super-resolution microscopy), and generation and analysis of lymphoma cells that have a complete deficiency of multiple Tspans (CRISPR/Cas9 technology). III. Decipher molecular mechanisms underlying Tspan web function in lymphoma cells (membrane organization, membrane-proximal signalling, metabolic reprogramming). With my unique toolbox of Tspan knock-outs coupled to advanced microscopy and metabolic studies, I expect that Secret Surface will lead to a new concept in cellular physiology in which cell surface organization by the Tspan web drives tumour development, which may open new horizons for the generation of new cancer therapies.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["724281"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["WEIZMANN INSTITUTE OF SCIENCE", "WEIZMANN INSTITUTE OF SCIENCE"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["ImmuNogenomics TArgeting Cancer"], "Total_Cost": ["EUR 150 000"], "Country": ["Israel", "Israel"], "Project_ACR": ["INTACt"], "Technology_Description": "Melanoma is the most aggressive, treatment-resistant and lethal type of skin cancer. Its increasing incidence worldwide emphasizes the need for new treatment strategies. Major recent breakthroughs in melanoma therapy have highlighted the role of immune T cell-mediated responses against tumor cells, showing that immune-system recognition of neo-antigens on cancer cells serves as a distinctive immunological signature. However, current strategies to identify neo-antigens are biased, costly and time-consuming. Directly addressing this major therapeutic limitation, this PoC project is aimed at commercializing an innovative tool, called INTACt, for designing highly personalized therapies for melanoma patients, ones that efficiently target the composition of patient-specific neo-antigens that arise as a consequence of mutations in a patient\u2019s melanoma genome. INTACt is designed to identify neo-antigens in a high-throughput, systematic and cost-effective manner in cell lines, fresh tumors, patient-derived xenografts and plasma. INTACt will further identify the patient neo-antigen-reactive T cells to then be returned to the patient, using neo-antigen-specific T cells or RNA vaccines. Such personalized targeting of the patient\u2019s melanoma genetic landscape is key to a significantly improved mortality. Unlike existing therapeutic strategies, INTACt may be considered the ultimate personalized immune therapy for the treatment of melanoma patients to be expended to other cancer types. This patient-specific tool will significantly lower patients\u2019 economic and psychological burden caused by unnecessary chemotherapy and targeted therapy. INTACt also holds the promise of realizing value from enormous past investments in drug candidates that were eliminated due to person-specific toxicities or lack of efficacy as these can be combined with the neo-antigen-based immunotherapy. INTACt will thus enable the creation of new business models for the highly pressured pharmaceutical industry.", "To": ["2018-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["754282"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY", "TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["User behavior Simulation in built Environments"], "Total_Cost": ["EUR 150 000"], "Country": ["Israel", "Israel"], "Project_ACR": ["USE"], "Technology_Description": "The impact of a building design or renovation on the behavior of its intended occupants can be assessed only after the building has been built and occupied (or the renovation has been completed). This is a risky proposition, because design mistakes can cause severe consequences in terms of under-performing buildings, reduced productivity, absenteeism, and general user dissatisfaction. During our ERC-funded project, titled NextGenBim, we were able to develop and demonstrate a method to computationally simulate human behavior in built environments, which allows representing the intended occupants and their activities in a given building. In this PoC we aim to develop a software simulator that allows: (1) to visualize, analyze and evaluate trade-offs between several design options for a new building; and (2) to evaluate the systemic implication of proposed renovations on the operations of a building. The software will potentially impact millions of professionals (architects, civil engineers, internal designers, facility mangers, etc.), especially in the healthcare sector, where large budgets are spent to build and renovate facilities, and in the educational sector, which invests heavily in computer-aided design software to train the next generation of professionals.", "To": ["2018-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["754696"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["STICHTING KATHOLIEKE UNIVERSITEIT BRABANT", "STICHTING KATHOLIEKE UNIVERSITEIT BRABANT"], "EU_Contribution": ["EUR 1 999 747,50"], "Project_Title": ["Innovative Methods for Psychology: Reproducible, Open, Valid, and Efficient"], "Total_Cost": ["EUR 1 999 747,50"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["IMPROVE"], "Technology_Description": "With numerous failures to replicate, common misreporting of results, widespread failure to publish non-significant results or to share data, and considerable potential bias due the flexibility of analyses of data and researcher\u2019s tendency to exploit that flexibility, psychological science is said to experience a crisis of confidence. These issues lead to dissemination of false positive results and inflate effect size estimates in meta-analyses. This leads to poor theory building, an inefficient scientific system, a waste of resources, lower trust in psychological science, and psychology\u2019s outcomes being less useful for society. After having contributed to the literature highlighting these problems the goal of my ERC project is to improve psychological science by offering novel solutions to five vexing challenges: (1) I want to counter misreporting of results by using our new tool statcheck in several studies on reviewers\u2019 tendency to demand perfection and by applying it to actual peer review. (2) I want to counter the biasing effects of common explorations of data (p-hacking) by professing and studying pre-registration and by developing promising new approaches called blind analysis and cross-validation using differential privacy that simultaneously allows for exploration and confirmation with the same data. (3) I want to counter the common problem of selective outcome reporting in psychological experiments by developing powerful latent variable methods that render it fruitless to not report all outcome variables in a study. (4) I want to counter the problem of publication bias by studying and correcting misinterpretations of non-significance. (5) I want to develop and refine meta-analytic methods that allow for the correction of biases that currently inflate estimates of effects and obscure moderation. The innovative tools I develop have the potential to improve the way psychologists (and other scientists) analyse data, disseminate findings, and draw inferences.", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["726361"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["TECHNISCHE UNIVERSITAET DRESDEN", "TECHNISCHE UNIVERSITAET DRESDEN"], "EU_Contribution": ["EUR 2 363 125"], "Project_Title": ["Understanding negative gas adsorption in highly porous networks for the design of pressure amplifying materials"], "Total_Cost": ["EUR 2 363 125"], "Country": ["Germany", "Germany"], "Project_ACR": ["AMPLIPORE"], "Technology_Description": "Negative gas adsorption (NGA) is a new, counterintuitive and paradoxical phenomenon, for the first time reported by my group in 2016: Normal solid materials with significant outer or inner surface area always take up gas when the pressure in the surrounding reservoir is increased (adsorption). NGA networks instead react at a certain point in the opposite direction: They release gas upon external pressure increase, leading to an overall pressure amplification in a closed system. Comparable phenomena have never been reported before. What is so exciting about NGA? We have a unique material in hand, that counteracts to an external force by force amplification.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["742743"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["ECOLE NORMALE SUPERIEURE", "ECOLE NORMALE SUPERIEURE"], "EU_Contribution": ["EUR 2 500 000"], "Project_Title": ["Molecules, magnetic fields and Intermittency in coSmic Turbulence \u2013 Following the energy trail."], "Total_Cost": ["EUR 2 500 000"], "Country": ["France", "France"], "Project_ACR": ["MIST"], "Technology_Description": "The discovery of molecules in the early universe is a challenging providence. Molecules unveil the truly cold universe in which stars form and their rich versatility provides unique diagnostics to unravel the \u201drelative importance of purely gravitational effects and gas dynamical effects involving dissipation and radiative cooling\u201d, recognized 40 years ago by White and Rees to be a central issue in theories of galaxy formation. Molecules also reveal that cosmic turbulence is far less dissipative than predicted by cosmological simulations, with a broad equipartition in a vast variety of media between the thermal energy of the hottest phases and the turbulent energy of the coldest. Our project focuses on the physics of turbulent dissipation, and its link to the emergence of molecules, in the magnetized compressible medium where gravitational instability develops to form stars and seed galaxies in the early universe. It builds on a fundamental property of turbulence, its space-time intermittency: dissipation occurs in bursts. Our team will foster strong interactions between three main research axes: (1) observations of the chemical and thermal markers of turbulent dissipation in the high-redshift and local universe, (2) statistical analyses of the magnetic and velocity fields in samples of unprecedented size and sensitivity to study the non-Gaussian signatures of turbulent dissipation, and (3) numerical experiments dedicated to (a) the space-time structures of turbulent dissipation and the formation of molecules in their wake, and (b) the split of the energy trails between hot/thermal and cold/turbulent phases. This project will benefit from the prodigious capabilities of the ALMA and NOEMA interferometers, the launch of the JWST in 2018, and the Planck satellite data on polarized Galactic foregrounds. The ENS Physics Department, with its strong theoretical and experimental expertise on turbulence, is an ideal place to house such a project.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["742719"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6", "UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6"], "EU_Contribution": ["EUR 2 192 500"], "Project_Title": ["Asymptotic approach to spatial and dynamical organizations"], "Total_Cost": ["EUR 2 192 500"], "Country": ["France", "France"], "Project_ACR": ["ADORA"], "Technology_Description": "The understanding of spatial, social and dynamical organization of large numbers of agents is presently a fundamental issue in modern science. ADORA focuses on problems motivated by biology because, more than anywhere else, access to precise and many data has opened the route to novel and complex biomathematical models. The problems we address are written in terms of nonlinear partial differential equations. The flux-limited Keller-Segel system, the integrate-and-fire Fokker-Planck equation, kinetic equations with internal state, nonlocal parabolic equations and constrained Hamilton-Jacobi equations are among examples of the equations under investigation. ", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["740623"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["OSPEDALE SAN RAFFAELE SRL", "OSPEDALE SAN RAFFAELE SRL"], "EU_Contribution": ["EUR 2 390 000"], "Project_Title": ["Functional Biology of Hepatic CD8+ T cells"], "Total_Cost": ["EUR 2 390 000"], "Country": ["Italy", "Italy"], "Project_ACR": ["FATE"], "Technology_Description": "CD8+ T cells have a key role in eliminating intracellular pathogens and tumors that affect the liver. The protective capacity of these cells relies on their ability to migrate to and traffic within the liver, recognize pathogen- or tumor-derived antigens, get activated and deploy effector functions. While some of the rules that characterize CD8+ T cell behavior in the infected and cancerous liver have been characterized at the population level, we have only limited knowledge of the precise dynamics of intrahepatic CD8+ T cell conduct at the single-cell level. In preliminary data for this project we have developed several advanced imaging techniques that allow us to dissect the interactive behavior of CD8+ T cells within the mouse liver at an unprecedented level of spatial and temporal resolution. We predict that this approach, combined with unique models of hepatitis B virus pathogenesis and a new model of hepatocellular carcinoma created ad hoc for this proposal, will generate novel mechanistic insights into the spatiotemporal determinants that govern the capacity of CD8+ T cells to home and function in the virus- or tumor-bearing liver. Specifically, we plan to pursue two main goals: 1) To assess how the anatomical, hemodynamic and environmental cues that characterize hepatocellular carcinomas shape CD8+ T cell behavior and function; 2) To characterize intrahepatic T cell priming events that induce functionally defective T cell responses. Results emerging from these studies will advance our knowledge on how adaptive immunity mediates pathogen clearance and tumor elimination. This new knowledge may lead to improved vaccination and treatment strategies for immunotherapy of infectious diseases and cancer.", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Italy"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-07-01"], "Project_ID": ["725038"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH", "3D PLUS SA", "JYVASKYLAN YLIOPISTO", "KATHOLIEKE UNIVERSITEIT LEUVEN", "RIJKSUNIVERSITEIT GRONINGEN", "UNIVERSITE DE MONTPELLIER", "FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG"], "EU_Contribution": ["EUR 3 889 953"], "Project_Title": ["RADiation and reliability challenges for electronics used in Space, Avionics, on the Ground and at Accelerators"], "Total_Cost": ["EUR 3 889 953"], "Country": ["Switzerland", "France", "Finland", "Belgium", "Netherlands", "France", "Germany"], "Project_ACR": ["RADSAGA"], "Technology_Description": "Reliability and radiation damage issues have a long and important history in the domain of satellites and space missions. Qualification standards were established and expertise was built up in space agencies (ESA), supporting institutes and organizations (CNES, DLR, etc.) as well as universities and specialized companies. During recent years, radiation concerns are gaining attention also in aviation, automotive, medical and other industrial sectors due to the growing ubiquity and complexity of electronic systems and their increased radiation sensitivity owing to technology scaling. This raises the demand for dedicated design and qualification guidelines, as well as associated technical expertise. Addressing open questions linked to respective qualification requirements, the proposed training network \u201cRADiation and Reliability", "To": ["2021-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Switzerland"], "Activity": ["Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-03-01"], "Project_ID": ["721624"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI GENOVA", "UNIVERSIDAD NACIONAL DE EDUCACION A DISTANCIA", "MIDDLE EAST TECHNICAL UNIVERSITY", "UNIVERSIDAD COMPLUTENSE DE MADRID", "UNIVERSIDADE DO MINHO", "UNIVERSITAT LINZ", "UNIVERSITA DEGLI STUDI DI BRESCIA", "ASSOCIAZIONE ITALIANA PER L ASSISTENZA AGLI SPASTICI PROVINCIA DI BOLOGNA", "FISH - FEDERAZIONE ITALIANA PER IL SUPERAMENTO DELL'HANDICAP ASSOCIAZIONE", "ASOCIACION DE FAMILIARES Y AMIGOS DE PERSONAS CON DISCAPACIDAD DE LA UNIVERSIDAD COMPLUTENSE DE MADRID (AFADIS UCM)", "FRATERNA - CENTRO COMUNITARIO DE SOLIDARIEDADE E INTEGRACAO SOCIAL, CIPRL", "VEREIN ZUR FOERDERUNG ASSISTIERENDER TECHNOLOGIE IN EUROPA", "FUNKA NU AB", "ENGELLI KADIN DERNEGI", "A.I.SM. ASSOCIAZIONE ITALIANA SCLEROSI MULTIPLA ONLUS", "STOCKHOLMS UNIVERSITET"], "EU_Contribution": ["EUR 1 809 000"], "Project_Title": ["RISEWISE -RISE Women with disabilities In Social Engagement"], "Total_Cost": ["EUR 1 809 000"], "Country": ["Italy", "Spain", "Turkey", "Spain", "Portugal", "Austria", "Italy", "Italy", "Italy", "Spain", "Portugal", "Austria", "Sweden", "Turkey", "Italy", "Sweden"], "Project_ACR": ["RISEWISE"], "Technology_Description": "Women with disabilities have more difficulties to find an employment and to integrate in social day life activities than men with disabilities.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other", "Other", "Other", "Other", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Other", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["690874"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Bridging Belief and Practice"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["BBP"], "Technology_Description": "The aim of the proposed research is to bridge the gap between theoretical and empirical studies of religion, which up till now developed separately, as the studies of beliefs and the studies of practices. This will be done by means of elucidating the properties of beliefs and their relation to human embodied religious practices. . I decided to take the best of empirical investigations (phenomenology and the most prominent results of religious studies) and the best of theoretical investigation (analytic philosophy) and make a conceptual work to bridge them. As a methodological basis for this work I have chosen embodied approaches, as they present a link between phenomenological descriptions and strict analytical conceptualizations. Body is a medium between beliefs and practices, thus the concept of belief will be developed in relation to the practice with a body as a focal point and a key source of conceptualizations. The results of the research will be presented in clear-cut analytical terms, easy to use not only by empirical and theoretical researchers of religion, but also by participants of interreligious dialogue, thus contributing to mutual understanding and religious tolerance. I aim to provide a proper, detailed and accurate account of the properties of beliefs in their relation to practice by conceptualizing the results of empirical studies in clear-cut analytical terms. This project is an important step in my professional development, as for its fulfillment I will have to apply all my previous knowledge and interdisciplinary skills, and learn new analytic methods.", "To": ["2017-09-27, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-28"], "Project_ID": ["660954"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["KOZEP-EUROPAI EGYETEM"], "EU_Contribution": ["EUR 146 239,20"], "Project_Title": ["Dynamics of Development: Understanding Adolescents' Intergroup Attitudes, National Feelings, and Perception of Social Norms"], "Total_Cost": ["EUR 146 239,20"], "Country": ["Hungary"], "Project_ACR": ["DYNADE"], "Technology_Description": "Understanding the causes of prejudice is one of the main goals of social psychology. Recently, the interest of researchers turned to the development of prejudice which is highly important for the early prevention of intergroup hostility. Most of these works focus on childhood and much less is known about the development of prejudice in adolescence even though it is a crucial period for the formation of the identity. In my previous research I was able to detect the process of the crystallisation of prejudice among teenagers. Comparing age groups between 12 and 19 years, teenagers\u2019 ethnic prejudices were found to become clearly more coherent by age. ", "To": ["2018-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Hungary"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["658323"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["TECHNISCHE UNIVERSITEIT EINDHOVEN", "INTEL BENELUX BV", "PHILIPS MEDICAL SYSTEMS NEDERLAND BV", "TECHNOLUTION BV", "TECHNISCHE UNIVERSITAET MUENCHEN", "INCHRON GMBH", "FORTISS GMBH", "TECHNISCHE UNIVERSITAT DORTMUND", "KUNGLIGA TEKNISKA HOEGSKOLAN", "IMSYS AB", "ODYS SRL"], "EU_Contribution": ["EUR 3 820 273,63"], "Project_Title": ["Platform-aware Model-driven Optimization of Cyber-Physical Systems"], "Total_Cost": ["EUR 3 820 273,63"], "Country": ["Netherlands", "Netherlands", "Netherlands", "Netherlands", "Germany", "Germany", "Germany", "Germany", "Sweden", "Sweden", "Italy"], "Project_ACR": ["oCPS"], "Technology_Description": "Many modern industrial systems fall in the realm of Cyber-Physical Systems (CPS) because of the tight interaction between computation, communication and control elements (the cyber part), and physical processes such as motion, heating/cooling, vibration, wear and tear (the physical part) within these systems. Traditional design methods involve multiple, often isolated, design phases involving different disciplines (mechanical, electrical, control and software engineering). Requirements related to cost, quality and reliability enforce designs with over-provisioning of platform resources (computation, communication, memory) by large margins at each phase to be able to fulfill system-level requirements in the worst-case scenarios. To replace such overly conservative design process, there is an urgent need for integrative design trajectories that allow for tradeoffs between cost, quality and reliability coping with the tight coordination between the cyber and the physical components. This gives rise to the need for models that accurately capture the interaction between various components (e.g., software, electronics, mechanics, algorithms, power, energy, etc.) and novel design methods that exploit the artifacts of the underlying platforms. ", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-11-01"], "Project_ID": ["674875"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Tracking discoursal shift in news media representation of economic inequality: developing and applying corpus linguistic and critical discourse analysis methods"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["DINEQ"], "Technology_Description": "DINEQ explores changes in the discoursal representation of degrees of economic inequality in selected British newspapers in 1971 and 2011. It is the first applied diachronic linguistic study to combine a consideration of the socio-political history in Britain in those forty years, a comparative analysis of selected public discourses in those two years, and a semantic, grammatical and lexical study of media representations of wealth inequality. The methodological approach used for this project is primarily Corpus Linguistic, but draws also on Systemic-Functional Grammar, and adopts a broadly Critical Discourse Analytic theory of discourse. The interdisciplinary nature of this project is complemented with the expertise of the Supervisor, Prof. Michael Toolan, and the Fellow, Dr. Eva Gomez, both experts in Stylistics and Discourse Analysis. The quality of the proposed project is ensured by the commitment of the members involved and the support committed by the University of Birmingham, one of the leading universities in Europe. This innovative study aims to demonstrate that rigorous and systematic corpus-based discourse analysis can establish discursive change over time, of a kind that is so dispersed and gradual that it is imperceptible in the day-to-day newspaper-reading of the ordinary reader.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["705247"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG", "RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG"], "EU_Contribution": ["EUR 1 896 250"], "Project_Title": ["The role of RNA in centromere biology and genome integrity"], "Total_Cost": ["EUR 1 896 250"], "Country": ["Germany", "Germany"], "Project_ACR": ["cenRNA"], "Technology_Description": "One of the most astonishing processes in the life of a cell is the division into two daughter cells. Such a highly organized process would presumably be regulated tightly by the underlying centromeric DNA sequence; however, the sites of chromosome attachment to the microtubule spindle are regulated by epigenetic mechanisms. The best-characterized epigenetic mark for centromeres is the histone H3-variant CENP-A, which replaces H3 in some of the nucleosomes within centromeric chromatin. Centromeres are embedded in pericentromeric heterochromatin and it has become apparent in recent years that heterochromatin is transcribed into non-coding RNAs. We have recently shown that a long non-coding RNA from pericentromeric heterochromatin of the X chromosome (SATIII) in Drosophila melanogaster localizes in trans to centromeres of all other chromosomes and is an essential component for correct loading and maintenance of CENP-A and, therefore, genome stability. Additional RNAs in Drosophila and RNAs from other species have been linked to centromeric chromatin, but their function is not understood. We propose that a complex, RNA-based epigenetic mechanism regulates centromere establishment and function. ", "To": ["2021-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-07-01"], "Project_ID": ["682496"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["GEANT VERENIGING", "EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH", "CESNET ZAJMOVE SDRUZENI PRAVNICKYCH OSOB", "CSC-TIETEEN TIETOTEKNIIKAN KESKUS OY", "DAASI INTERNATIONAL GMBH", "VEREIN ZUR FOERDERUNG EINES DEUTSCHEN FORSCHUNGSNETZES DFN VEREIN E.V.", "STICHTING EGI", "CONSORTIUM GARR", "ETHNIKO DIKTYO EREVNAS TECHNOLOGIAS AE", "JISC COLLECTIONS AND JANET LIMITEDLBG", "FORSCHUNGSZENTRUM JULICH GMBH", "KARLSRUHER INSTITUT FUER TECHNOLOGIE", "STICHTING LIBER", "MORAVSKA ZEMSKA KNIHOVNA V BRNE", "STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN", "INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK", "GROUPEMENT D INTERET PUBLIC POUR LERESEAU NATIONAL DE TELECOMMUNICATIONS POUR LA TECHNOLOGIE L ENSEIGNEMENT ET LA RECHERCHE", "SCIENCE AND TECHNOLOGY FACILITIES COUNCIL", "SURFnet bv", "SURFSARA BV"], "EU_Contribution": ["EUR 2 941 060"], "Project_Title": ["Authentication and Authorisation for Research and Collaboration (AARC)"], "Total_Cost": ["EUR 2 950 060"], "Country": ["Netherlands", "Switzerland", "Czech Republic", "Finland", "Germany", "Germany", "Netherlands", "Italy", "Greece", "United Kingdom", "Germany", "Germany", "Netherlands", "Czech Republic", "Netherlands", "Poland", "France", "United Kingdom", "Netherlands", "Netherlands"], "Project_ACR": ["AARC"], "Technology_Description": "The goal of AARC is to address technical and functional gaps that prevent the interoperability of existing R&E AAIs. ", "To": ["2017-04-30, closed project"], "Meta": [""], "Topic_s": ["EINFRA-7-2014 - Provision of core services across e-infrastructures"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Netherlands"], "Activity": ["Other", "Research Organisations", "Research Organisations", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Other", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Research Organisations", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-05-01"], "Project_ID": ["653965"], "Call_for_Proposal": ["H2020-EINFRA-2014-2"]}, -{"Partners": ["\"NATIONAL CENTER FOR SCIENTIFIC RESEARCH \"\"DEMOKRITOS\"\"\"", "EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH", "KOBENHAVNS UNIVERSITET", "A I ALIKHANYAN NATIONAL SCIENCE LABORATORY", "NANJING UNIVERSITY", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "NATIONAL ACADEMY OF SCIENCES OF THE REPUBLIC OF ARMENIA"], "EU_Contribution": ["EUR 252 000"], "Project_Title": ["Development and Implementation of new generation of Pseudo Random Number Generators based on Kolmogorov-Anosov K-systems"], "Total_Cost": ["EUR 360 000"], "Country": ["Greece", "Switzerland", "Denmark", "Armenia", "China", "Switzerland", "Armenia"], "Project_ACR": ["MIXMAX"], "Technology_Description": "Modern powerful computers open a new era for the application of the Monte Carlo method for the simulation of physical systems of higher complexity. The Monte Carlo simulations are important computational techniques in many areas of natural sciences and have significant application in particle and nuclear physics, quantum physics, statistical physics, quantum chemistry, material science, among many other multidisciplinary applications. In the heart of the Monte Carlo simulations are Pseudo Random Number Generators (RNG). The primary objective of the proposed network is a systematic development and implementation of the state of the art new generation of Pseudo Random Number Generators based on Kolmogorov-Anosov K-systems, which demonstrates excellent statistical properties, into a multidisciplinary usable product. This innovative class of RNG was proposed earlier by the members of the network and relies on the fundamental discoveries and results of Ergodic theory. In order to turn these ideas and earlier research on K-systems generators into a usable product the network undertakes the following actions: To develop an efficient program of the K-system generator with tunable internal parameters of maximal dimensionality and of the order of the Galois field, embedded into a user friendly environment and with an on-line manual; To provide statistical data representing internal characteristics of the K-system generator as a function of the dimensionality of the generator and of the order of the Galois field; To implement the K-system generator into the concurrent and distributed software at CERN for applications in LHC and other HEP experiments; To perform large scale simulations in Quantum Gravity and Quantum Field Theory based on K-system generator. To disseminate the product at CERN and other research centers.These objectives will be achieved by secondments,exchange of knowledge, collective research and training between staff members of the five partners.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Greece"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-01-01"], "Project_ID": ["644121"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["UNIVERSITEIT UTRECHT", "UNIVERSITEIT UTRECHT"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Addressing Antibiotic Resistance: New Strategies for Overcoming the ESKAPE Pathogens"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["NO-ESKAPE"], "Technology_Description": "Antibiotic resistance poses an alarming threat to global health. Most worrisome are the so-called \u201cESKAPE\u201d pathogens (E. faecium, S. aureus, K. pneumoniae, A. baumanii, P. aeruginosa, and Enterobacter species), a collection of organisms capable of escaping the effects of almost all conventional antibiotics. Key to combating drug-resistant bacteria is the identification of new antibacterial targets and the ability to exploit these targets with novel and unconventional antibiotics.", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["725523"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Calibration of Astronomical Spectrographs with Stabilized Fabry-Perot Etalons"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["STABLE_FABRY"], "Technology_Description": "The \u201choly grail\u201d of exoplanet research today is the detection of an Earth-like planet in the habitable zone of a Sun-like star. Doppler spectroscopy is an indispensable tool for finding and characterizing extrasolar planets; however, detecting an Earth twin by measuring the radial velocity (RV) perturbation it imposes on the parent star requires nearly one order of magnitude better RV precision than the best current spectrographs provide. A key component in addressing the limitations of existing instruments is the development of extremely precise calibration light sources that can be used to track drifts and imperfections of the spectrograph, removing them from the science data. A stable, reliable, and relatively inexpensive calibrator solves a \u201cchicken and egg\u201d problem in the field \u2013 motivating the building of more stable spectrographs, secure in the knowledge that they will be able to perform to their potential. Project STABLE_FABRY consists of developing a novel calibration technique that can be applied to a wide range of high resolution spectrographs. This technique uses a broadband Fabry-Perot etalon to provide the calibration spectrum; the etalon is stabilized by referencing it to an atomic transition using standard laser spectroscopy methods. Our preliminary work already indicates that a stability of 3 cm/s can be reached with this method, making it precise enough for detection of Earth-like planets. The only other currently available calibration technology with demonstrated precision at that level is the laser frequency comb, which is an order of magnitude more complex and significantly more expensive. Our technique can easily be adapted to different echelle spectrographs in the visible and near infrared by simply using an etalon optimized for that particular spectrograph. Developing this concept into an observatory-ready system will present a major breakthrough for high precision spectrographs, enabling detections of Earth twins with Doppler spectroscopy.", "To": ["2018-04-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-04-15"], "Project_ID": ["659985"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["PAUL SCHERRER INSTITUT", "PAUL SCHERRER INSTITUT"], "EU_Contribution": ["EUR 2 328 648,75"], "Project_Title": ["Hyper Quantum Criticality"], "Total_Cost": ["EUR 2 328 648,75"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["HyperQC"], "Technology_Description": "Hyper Quantum Criticality \u2013 HyperQC is a major initiative with the aim of generating and controlling novel phases of correlated magnetic quantum matter, and of exploring them in high-precision experiments. A combination of new capabilities enabled by the development of instrumentation, pioneering ultra-fast studies and experiments on magnetic model materials will allow both the exploration of fundamental Hamiltonians and fully quantitative tests of quantum criticality in hyper-parameter space: temperature, magnetic field, pressure, energy, momentum and time. ", "To": ["2021-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2016-12-01"], "Project_ID": ["681654"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["FUNDACION BCMATERIALS - BASQUE CENTRE FOR MATERIALS, APPLICATIONS AND NANOSTRUCTURES"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Smart Alloys Surface Patterning for Properties Tuning"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["SASPAT"], "Technology_Description": "The SASPAT project presents two main goals: (a) to train the talented young researcher Dr. Jose M. Porro, in the attractive growing field of Magnetic Shape Memory Alloys (MSMAs), where the host and partner institutions have developed their expertise and knowledge; and (b) the design, development and optimisation of smart patterned MSMA surfaces for applications in industrial sectors such as microfluidics and optical microswitching.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-10-01"], "Project_ID": ["753025"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG", "RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG"], "EU_Contribution": ["EUR 2 390 000"], "Project_Title": ["Entanglement Generation in Universal Quantum Dynamics"], "Total_Cost": ["EUR 2 390 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["EntangleGen"], "Technology_Description": "A paradigm example of precise predictions in complex systems is the universal scaling of correlation functions close to phase transitions, with their associated critical exponents. The extension of this concept to time dependent problems has been studied in the classical regime as well as in the quantum regime. A clean experimental confirmation of this prediction in a quantum system as well as of its connection to non-local entanglement generation is the defined goal of this project.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["694561"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Atom-by-Atom Quantum Control of Fermions in Arbitrary Potentials"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["FermiTrap"], "Technology_Description": "The behavior of many-body quantum systems is one of the most difficult problems in modern physics. An interesting and open question is how the properties of a complex many-body system depend on its constituents, and how collective behavior emerges from the underlying few-particle building blocks. Ultracold atoms offer the unique possibility to realize well-controlled quantum systems and study this question directly in the laboratory. We propose a highly adaptable approach to assembling systems of few ultracold fermions in optical micro traps. Using a spatial light modulator, we will implement arbitrary trapping potentials and small optical lattices with novel geometries. A near-deterministic loading scheme will initialize states with extremely low entropies and realize previously inaccessible quantum states. We will perform detailed measurements of static and dynamic spin orderings on small Mott insulating plaquettes and realize unusual cylindrical optical lattices with periodic boundary conditions. Our approach is complementary to many traditional optical lattice experiments and will generate wide interest in mesoscopic Fermi systems.", "To": ["2018-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-04-01"], "Project_ID": ["706487"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIWERSYTET WARSZAWSKI", "UNIWERSYTET WARSZAWSKI"], "EU_Contribution": ["EUR 1 768 125"], "Project_Title": ["A unified theory of finite-state recognisability"], "Total_Cost": ["EUR 1 768 125"], "Country": ["Poland", "Poland"], "Project_ACR": ["LIPA"], "Technology_Description": "Finite-state devices like finite automata and monoids on finite words, or extensions to trees and infinite objects, are fundamental tools of logic in computer science. There are tens of models in the literature, ranging from finite automata on finite words to weighted automata on infinite trees. Many existing finite-state models share important similarities, like existence of canonical (minimal) devices, or decidability of emptiness, or a logic-automata connection. The first and primary goal of this project is to systematically investigate these similarities, and create a unified theory of finite-state devices, which:", "To": ["2021-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Poland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["683080"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY", "TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY"], "EU_Contribution": ["EUR 2 624 517"], "Project_Title": ["Advanced holographic optical neural stimulation for vision restoration and basic research"], "Total_Cost": ["EUR 2 624 517"], "Country": ["Israel", "Israel"], "Project_ACR": ["HoloVision"], "Technology_Description": "When natural sensory input is disrupted, as in outer-retinal degenerative diseases, artificial stimulation of surviving nerve cells offers a potential strategy for bypassing compromised neural circuits and substituting sensory perception. Current neuro-stimulation interfaces that use electrical currents from micro-electrode arrays are already being clinically applied for retinal stimulation, but their performance is ultimately limited by current spread and the requirement for physical contact with an implanted device. Future minimally-invasive systems could use light patterns to photo-induce complex yet precise spatio-temporal activity patterns among surviving retinal neurons, with the ultimate potential of restoring vision to a nearly normal level. ", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["648927"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["ACADEMISCH ZIEKENHUIS GRONINGEN", "OTTO-VON-GUERICKE-UNIVERSITAET MAGDEBURG", "Academisch Medisch Centrum bij de Universiteit van Amsterdam", "CITY UNIVERSITY OF LONDON", "OCUSPECTO OY", "IMPLANDATA OPHTALMIC PRODUCTS GMBH", "UNIVERSITE CLERMONT AUVERGNE", "UNIVERSITE D'AUVERGNE CLERMONT-FERRAND 1", "ECHODIA"], "EU_Contribution": ["EUR 3 870 583,92"], "Project_Title": ["European Glaucoma Research Training Program-Plus"], "Total_Cost": ["EUR 3 870 583,92"], "Country": ["Netherlands", "Germany", "Netherlands", "United Kingdom", "Finland", "Germany", "France", "France", "France"], "Project_ACR": ["EGRET-Plus"], "Technology_Description": "Glaucoma is the most common age-related neurodegenerative eye-disease in western society and one of the four major blinding eye diseases. If untreated or detected too late, glaucoma will end in blindness, yielding a profound loss of quality of life for the individual and major costs to society. Given the vast complexity of glaucoma, to advance assessment and therapy beyond the current state-of-the-art, we need a new generation of researchers who are deeply knowledgeable about and intimately familiar with the many different approaches for study all aspects of glaucoma and the aging visual system: from functional test to anatomy, from gene to ganglion cell, from retina to brain. However, current knowledge is fragmented and so is the corresponding training. Very few researchers have been adequately trained which severely limits progress. Well-trained teams of dedicated glaucoma researchers are pivotal to integrate and extend the highly specialized knowledge, and to make a real difference for the patient.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-01-01"], "Project_ID": ["675033"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSITAET HAMBURG", "UNIVERSITY OF LEEDS", "UNIVERSITY OF GLASGOW", "FORSCHUNGSZENTRUM JULICH GMBH", "CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL", "PAUL SCHERRER INSTITUT"], "EU_Contribution": ["EUR 3 396 439,10"], "Project_Title": ["Magnetic Skyrmions for Future Nanospintronic Devices"], "Total_Cost": ["EUR 3 396 439,60"], "Country": ["France", "Germany", "United Kingdom", "United Kingdom", "Germany", "Germany", "Switzerland"], "Project_ACR": ["MAGicSky"], "Technology_Description": "Challenges facing technology for power efficient, high density, high speed information processing and storage are well recognised, and strategies for meeting them in the short term define the shape of industry roadmaps. As a consequence, in the next ten years, radically new approaches will be implemented and will transform how data is stored and manipulated. Skyrmion-based devices are newcomers to this global race for the next generations of information technology. Skyrmions were discovered in magnetic crystals only a few years ago, but we already have within reach a possibility to create them in nanoscale devices that can be made compatible with conventional integrated circuit technology. Our work in MAGicSky will substantiate this possibility.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-1-2014 - FET-Open research projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2015-09-01"], "Project_ID": ["665095"], "Call_for_Proposal": ["H2020-FETOPEN-2014-2015-RIA"]}, -{"Partners": ["RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG", "RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG"], "EU_Contribution": ["EUR 2 500 000"], "Project_Title": ["Efficient pathways to neutralization and radical production enabled by environment"], "Total_Cost": ["EUR 2 500 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["ETMD_ICEC"], "Technology_Description": "The relaxation of electronically excited systems like atoms and molecules embedded in environment is a key question in chemistry and photobiology and the underlying physical mechanisms have been widely studied. The applicant has predicted theoretically that there are two efficient electronic processes between a system and its neighbors even if the system itself is in its electronic ground state and does not have excess energy, making clear that an important gap exists in our current understanding of systems embedded in environment. There is extensive future potential in filling this gap and we aim at exploring and exploiting it in systems of physical, chemical, and biological interest. The discovered electron-transfer mediated decay (ETMD) [several variants of ETMD have been already verified experimentally] and intermolecular Coulombic electron capture (ICEC) mechanisms give rise to a plethora of surprising electronic phenomena relevant to many fields. In radiation damage, for instance, differently charged cations and electrons are produced by ionization and Auger processes, and ETMD and ICEC continue to be operative, neutralize cations and produce radicals in the environment also after the known mechanisms of radiation damage have ceased to operate. This leads to severe additional damage. Knowing the factors influencing the impact of ETMD and ICEC most, we can exploit this knowledge to be able to suppress or enhance this impact. Such a control is invaluable in many cases, may be even in radiation therapy. We are certain that the novel and fundamental ETMD and ICEC processes can be exploited to probe and control systems embedded in an environment. Such a breakthrough necessitates the advancement of current methodologies far beyond the state-of-the-art, and can only be achieved by the close collaboration of a highly motivated strong team of scientists over a long period of time. The support by the ERC will substantially contribute to the realization of this vision.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["692657"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["CESKE VYSOKE UCENI TECHNICKE V PRAZE", "CESKE VYSOKE UCENI TECHNICKE V PRAZE"], "EU_Contribution": ["EUR 1 499 500"], "Project_Title": ["Artificial Intelligence for Large-Scale Computer-Assisted Reasoning"], "Total_Cost": ["EUR 1 499 500"], "Country": ["Czech Republic", "Czech Republic"], "Project_ACR": ["AI4REASON"], "Technology_Description": "The goal of the AI4REASON project is a breakthrough in what is considered a very hard problem in AI and automation of reasoning, namely the problem of automatically proving theorems in large and complex theories. Such complex formal theories arise in projects aimed at verification of today's advanced mathematics such as the Formal Proof of the Kepler Conjecture (Flyspeck), verification of software and hardware designs such as the seL4 operating system kernel, and verification of other advanced systems and technologies on which today's information society critically depends.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Czech Republic"], "Activity": ["Higher or Secondary Education Establishments", "Jiri Matas", "Tel.: +420 22435721", "Fax: +420 224357385", "Higher or Secondary Education Establishments", "Jiri Matas", "Tel.: +420 22435721", "Fax: +420 224357385"], "From": ["2015-09-01"], "Project_ID": ["649043"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSITAET POTSDAM", "UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 1 999 999,33"], "Project_Title": ["Monsoons of Asia caused Greenhouse to Icehouse Cooling"], "Total_Cost": ["EUR 1 999 999,33"], "Country": ["France", "France", "Germany", "Netherlands"], "Project_ACR": ["MAGIC"], "Technology_Description": "Unraveling the cause for Cenozoic global climate cooling is one of the most important unresolved questions challenging the Earth and Environmental sciences community today. Increased erosion and weathering of the uplifted Tibetan Plateau and Himalayas, is advocated as the primary cause for the enigmatic pCO2 drawdown, that led to global cooling 50 to 34 Myrs ago from the warm ice-free Greenhouse world to the bi-polar Icehouse conditions still prevailing today. Asian Monsoons are genetically linked to high orography associated with the India-Asia collision starting ca. 50 Myrs ago, however, the relation between Greenhouse to Icehouse cooling and Asian Monsoons remains to be explore as they were previously thought to intensify only much later ca. 25 Myrs ago. Our recent findings of monsoonal activity in Asia since at least 45 Myrs ago raises the fascinating possibility that Asian Monsoons may have triggered global cooling from Greenhouse to Icehouse conditions. Testing this novel hypothesis and exploring its implications on feedback mechanisms between regional environments, Asian Monsoons and global climate, will constitute the stimulating objectives of MAGIC. 3 PhDs will provide end-member monsoonal archives well-dated during greenhouse to icehouse cooling from 3 key locations (NE Tibet, SE Asia and Paratethys Sea). These will be analyzed by three postdocs expert in novel proxy methods tailored for MAGIC to infer temperatures, precipitation, salinity, seasonality, paleoaltimetry, wind-patterns, paleoecology and paleogeography at infra-annual, orbital and tectonic time scales. Ultimately, these records and boundary conditions will be integrated into climate models by a dedicated postdoc to unravel the role and behavior of Asian Monsoons with respect to long-term Greenhouse to Icehouse cooling, pCO2 levels as well as global hyperthermal and cooling event such as the PETM, MECO and EOT.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["649081"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "FREIE UNIVERSITAET BERLIN", "CONSIGLIO NAZIONALE DELLE RICERCHE", "LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN", "TECHNISCHE UNIVERSITAET WIEN"], "EU_Contribution": ["EUR 2 000 500"], "Project_Title": ["Analog quantum simulators for many-body dynamics"], "Total_Cost": ["EUR 2 000 500"], "Country": ["Germany", "France", "Germany", "Italy", "Germany", "Austria"], "Project_ACR": ["AQuS"], "Technology_Description": "Quantum simulators promise to provide unprecedented insights into physical phenomena not accessible with classical computers and have the potential to enable radically new technologies. In this proposal, we argue that analog dynamical quantum simulators are currently realisable and constitute a most promising class of architectures to fulfil the ultimate promise to devise quantum machines outperforming classical computers. The approach taken is two-pronged: On the one hand, we devise versatile and practical platforms for dynamical simulators \u2013 making use of systems of ultra-cold atoms in optical lattices and the continuum, as well as cavity polaritons. We suggest a concerted and interdisciplinary research programme of certifying quantum devices and assess them in their computational capabilities, addressing largely unexplored key questions on the power of quantum simulators. On the other, we make use of those devices to probe important questions in fundamental and applied physics, ranging from technology-relevant problems, concerning transport processes or glassy dynamics, via long-standing challenges in the physics of non-equilibrium and thermalisation phenomena, through puzzles in notions of quantum turbulence, to questions in the study of quantum gravity.", "To": ["2017-12-31, closed project"], "Meta": [""], "Topic_s": ["FETPROACT-3-2014 - Quantum simulation"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-01-01"], "Project_ID": ["640800"], "Call_for_Proposal": ["H2020-FETPROACT-2014"]}, -{"Partners": ["RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG", "RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG"], "EU_Contribution": ["EUR 1 999 000"], "Project_Title": ["Decoding the Lateral Expansion of Plant Stems"], "Total_Cost": ["EUR 1 999 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["PLANTSTEMS"], "Technology_Description": "In contrast to animals, in which tissue proliferation in adult individuals is often pathological and deleterious, plants have evolved an indefinite growth habit. A remarkable but under-investigated example is the thickening of plant stems and roots: It is a purely postembryonic growth process and the group of stem cells responsible \u2013 the cambium \u2013 is derived from and embedded in fully differentiated tissues. Consequently, lateral plant growth has to integrate and overcome developmental and physical constraints imposed by participating tissues. This is especially significant in the context of the extracellular matrix, which fixes the position of plant cells relative to each other and provides mechanical support for the plant body. However, how cells sense and modulate their environment during this process is completely unknown. Here, I will leverage the unique growth mode of plants and explore the process of lateral stem growth in the reference plant Arabidopsis thaliana as a paradigm for postembryonic growth and tissue remodelling. Thereby I will address the fundamental question of how cell identities are reprogrammed in vivo and how basic cellular functions like interaction between cells and their matrix contribute to this process. To achieve this I will i) decipher the influence of the extracellular matrix on stem cell activity by cell type-specific modulation of matrix integrity; ii) decode the complex role of brassinosteroid hormones by tuning their activities during stem cell initiation; iii) record cell fate signatures by high-resolution 4-D expression maps for cambium subdomains; and iv) Identify novel signalling cascades connecting the extracellular matrix with underlying cells by forward genetics. Together my results will provide unprecedented insight into lateral stem growth \u2013 a process responsible for the accumulation of wood and a large proportion of terrestrial biomass and will reveal fundamental concepts of growth processes in adult organisms.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["647148"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["\"NATIONAL CENTER FOR SCIENTIFIC RESEARCH \"\"DEMOKRITOS\"\"\"", "\"NATIONAL CENTER FOR SCIENTIFIC RESEARCH \"\"DEMOKRITOS\"\"\""], "EU_Contribution": ["EUR 148 250"], "Project_Title": ["A lab-on-chip platform for blood cell counting and identification at the point-of-care"], "Total_Cost": ["EUR 148 250"], "Country": ["Greece", "Greece"], "Project_ACR": ["pocL-CI"], "Technology_Description": "Blood cell counting/identification is the most powerful and widespread approach throughout the world for assessing an individual\u2019s health status. The diagnosis and monitoring of an infection (e.g. HIV, malaria, bacterial infection), the monitor of a chemotherapy outcome (e.g. in cancer patients) or even the diagnosis of rare diseases (e.g. sickle cell disease, non-Hodgkin lymphomas), relies on analysing the number and/or the morphology of different types of blood cells. Here, we aim to validate a portable, single-cell counting/identification platform that can be used to diagnose and monitor diseases at the point-of-care. The platform consists of a low-cost, handheld, battery-operated, scanner and a disposable microfluidic biochip. The underlying technology, termed \u2018Label-free Cell Identification (L-CI) technology\u2019, is based on the integration of novel, microfabricated components that enable to simultaneously image and count thousands of cells at high spatial resolution. If successfully commercialized, the L-CI platform will be the first medical instrument to perform a blood cell counting test by the end user at home, in few minutes. The potential is enormous as the L-CI platform will replace millions of blood cell tests that routinely performed by trained personnel in clinics and hospitals in the developed world but it will also make blood cell tests available in the developing wold.", "To": ["2017-12-31, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2015 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Greece"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2016-07-01"], "Project_ID": ["693433"], "Call_for_Proposal": ["ERC-2015-PoC"]}, -{"Partners": ["HELSINGIN YLIOPISTO"], "EU_Contribution": ["EUR 265 082,40"], "Project_Title": ["Formation of nano-scale clusters from atmospheric vapors"], "Total_Cost": ["EUR 265 082,40"], "Country": ["Finland"], "Project_ACR": ["nanoCAVa"], "Technology_Description": "This research concentrates on advancing the understanding of the border between the gas and condensed phase by studying the formation of nanoscale clusters from atmospheric vapours (NanoCAVa). Cluster formation and growth is a crucial step in forming new aerosol particles in the atmosphere. We aim to resolve the role of molecular clusters in aerosol formation by targeted field measurements at various locations and precisely controlled chamber experiments. Using and further developing the latest measurement technology, and combining physical and chemical information, enables us to get a full characterization of neutral clusters, which is so far lacking. We utilize the results to create a better description of the dynamics of 1 \u2013 5 nm nano-particles, which often cannot be treated with traditional theories, and to implement the concept of a cluster mode into the general view on the atmospheric aerosol size distribution. Understanding the factors controlling the growth of newly formed clusters into climatically relevant particles and cloud condensation nuclei (CCN) enables estimating their importance in the climate system more accurately. This project will facilitate the ER to pursue a successful research career in atmospheric science and establish her position as an expert of nano-particle measurement technology. It will also strengthen the role of the beneficiary and the partner organization as the leading groups in atmospheric nucleation research and their mutual collaboration.", "To": ["2018-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-08-01"], "Project_ID": ["656994"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG", "RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG"], "EU_Contribution": ["EUR 147 968"], "Project_Title": ["Novel enhancers of functional recovery after stroke"], "Total_Cost": ["EUR 147 968,50"], "Country": ["Germany", "Germany"], "Project_ACR": ["VEGFDANI"], "Technology_Description": "Several forms of neuroadaptation are controlled by transient increases in the nuclear calcium concentration. Nuclear calcium regulates expression of crucial genes and alterations of this signaling network likely underlie many neurological disorders. Our work led us to design two innovative strategies exploiting the therapeutic potential of nuclear calcium signaling: 1-developing direct nuclear calcium signaling activators/inhibitors (NCSA/I) and 2-manipulating expression and/or function of nuclear calcium targets. ", "To": ["2016-08-31, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2014 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-03-01"], "Project_ID": ["640892"], "Call_for_Proposal": ["ERC-2014-PoC"]}, -{"Partners": ["RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Printed Optoelectronic Devices from Nanosheet Network Electrochemically-gated Field Effect Transistors"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["2D-EG-FET"], "Technology_Description": "Much research is underway to create a new class of inexpensive electronic devices fabricated by printing combinations of nanomaterial- & functional polymer-inks onto arbitrary substrates, such as everyday plastic film. This will open a route to a wide range of electronic, optoelectronic & electrochemical applications that are impossible using conventional silicon-based manufacturing approaches. For example, it will enable devices that are mechanically deformable (i.e. flexible or stretchable), optically transparent, or even cheap enough to be considered disposable. Innovative features such as these will enable electronic functionality to be integrated into locations where they are currently not feasible. As such, these printed electronics technologies will have applications in many areas of concern for modern society such as public security, healthcare & environmental protection. Here we aim to fabricate aerosol-jet printed ensembles of semiconductor nanosheets (i.e. nanosheet networks) with controlled composition & morphology, then fabricate these into electrochemically-gated field-effect transistors (E-gated FETs). This will enable the study of electronic transport, charge separation & recombination processes that occur within these networks with the view to apply them within cheap, printable photodetector & electroluminescent devices.", "To": ["2018-05-15, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-05-16"], "Project_ID": ["707644"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["PAUL SCHERRER INSTITUT"], "EU_Contribution": ["EUR 4 248 000"], "Project_Title": ["International, Interdisciplinary and Intersectoral Postdocs"], "Total_Cost": ["EUR 8 496 000"], "Country": ["Switzerland"], "Project_ACR": ["PSI-FELLOW-II-3i"], "Technology_Description": "Large-scale research facilities are enabling cutting edge research and innovation in important domains such as materials science, health and energy. A number of such accelerator facilities is currently under construction in Europe and will become operational within the next ten years. Thus, there is a growing need for highly qualified researchers trained in interdisciplinary research at such facilities and also an increasing demand from companies to use these facilities for developing and testing innovative products.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2015-FP - Marie Sk\u0142odowska-Curie Co-funding of regional, national and international programmes (COFUND-FP)"], "Funding_scheme": ["MSCA-COFUND-FP - Fellowship programmes"], "Coordinated_in": ["Switzerland"], "Activity": ["Research Organisations"], "From": ["2016-10-01"], "Project_ID": ["701647"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2015"]}, -{"Partners": ["PANTEIO PANEPISTIMIO KOINONIKON KAIPOLITIKON EPISTIMON"], "EU_Contribution": ["EUR 164 653,20"], "Project_Title": ["Forecasting oil prices, oil price volatility and economic policy uncertainty"], "Total_Cost": ["EUR 164 653,20"], "Country": ["Greece"], "Project_ACR": ["ENEFOR"], "Technology_Description": "Oil price and oil price volatility forecasts are of major importance, given the oil market is well crowded by participants who proceed to decisions based on these forecasts (e.g. oil traders, monetary policy authorities, etc). The current state-of-the-art forecasting techniques, though, (i) involve a trade-off among internal consistency, forecasting accuracy and easiness to communicate aspects and (ii) do not use ultra high frequency data. Thus, this exciting and innovative project aims to develop new econometric model frameworks to forecast oil price and oil price volatility, which will be successful in enhancing internal consistency, forecasting accuracy and easiness to communicate extracting added-value (in terms of predictability) information from the ultra high sampling frequency. In addition, this project aims to use the forecasted oil price volatility to predict the economic policy uncertainty in Europe, given that oil price shocks exert significant impact on the effectiveness of economic policy. This project will allow the researcher to advance his existing scientific and transferable skills through the cutting-edge training in the state-of-the-art forecasting techniques, as well as, in programming, consultancy and policy formulation skills. The outcome of this training (i) will provide the fellow with an invaluable opportunity for the development of a pioneering research agenda and (ii) will position him as an internationally recognised scholar that contributes to research excellence in Europe. The established capacity of the fellow as an independent researcher in the area of energy economics, the expertise of the scientist-in-charge in state-of-the-art forecasting techniques and the infrastructure of the host organisation offer great complementarities, which will allow these highly innovative model frameworks to be realised. This project will have a great impact not only to the researcher, but also to the host organisation and to the European Research Area", "To": ["2017-04-05, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Greece"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-04-06"], "Project_ID": ["658494"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "LEIBNIZ INSTITUT FUER TROPOSPHAERENFORSCHUNG e.V.", "IONICON ANALYTIK GMBH", "UNIVERSITE D'ORLEANS"], "EU_Contribution": ["EUR 1 080 000"], "Project_Title": ["MARine atmospheric Science Unravelled: Analytical and mass spectrometric techniques development and application"], "Total_Cost": ["EUR 1 269 000"], "Country": ["France", "Germany", "Austria", "France"], "Project_ACR": ["MARSU"], "Technology_Description": "MARSU is a collaborative (4 Member States , including one participant from the non-academic sector, and six Third Countries from South America, Africa and Asia) with the goal of gaining new knowledge and reducing the uncertainty about the effect of aerosols deriving from the air-sea exchange on climate and atmospheric composition connected to air pollution. The results from this key interdisciplinary project will have impact on current and future industrial and legislative developments.", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2016-02-01"], "Project_ID": ["690958"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA", "SHAPE IDIOTIKI KEFALAIOUCHIKI ETAIRIA", "AMERICAN COMPUTERS AND ENGINEERS HELLAS SA", "ECOLE POLYTECHNIQUE", "UNIVERSITE PARIS DIDEROT - PARIS 7", "INSTITUT POLYTECHNIQUE DE GRENOBLE", "UNIVERSITY OF CYPRUS", "GEDIZ UNIVERSITESI", "IZMIR INSTITUTE OF TECHNOLOGY", "IOPTI", "YASAR UNIVERSITESI", "EUPRAXIA LIMITED"], "EU_Contribution": ["EUR 1 620 000"], "Project_Title": ["Optimization Driven Architectural Design of Structures"], "Total_Cost": ["EUR 1 620 000"], "Country": ["Greece", "Greece", "Greece", "France", "France", "France", "Cyprus", "Turkey", "Turkey", "France", "Turkey", "Cyprus"], "Project_ACR": ["OptArch"], "Technology_Description": "\"According to UNEP, the building sector is estimated to be worth 10% of the global GDP and employs 111 million people. In addition, buildings use about 40% of global energy, 40% of global resources and emit approximately 33% of global GHG emissions. Finally, the fact that people today spend, on average, more than 80% of their time indoors, enhances its social importance. All above indicate the necessity to optimize building design.", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Greece"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-02-01"], "Project_ID": ["689983"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE"], "EU_Contribution": ["EUR 243 934,20"], "Project_Title": ["Russia's strategic narrative of the West: A study of influence in Ukraine"], "Total_Cost": ["EUR 243 934,20"], "Country": ["United Kingdom"], "Project_ACR": ["STRATNARRA"], "Technology_Description": "This project investigates the relationship between mass communication and influence in 21st Century international relations. It does so through a study of Russia\u2019s official and media narratives about the West and their reception in Ukraine. Success in today\u2019s information age is said to depend on \u2018whose story wins\u2019. Emerging powers such as Russia have developed various policies and instruments under the banner of \u2018soft power\u2019 to challenge Western hegemony in global media discourse. The projection of counter-hegemonic narratives has been documented extensively, yet we still understand little about their reception and the extent of their influence among target audiences.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["654020"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["FUNDACION BCMATERIALS - BASQUE CENTRE FOR MATERIALS, APPLICATIONS AND NANOSTRUCTURES", "\"NATIONAL CENTER FOR SCIENTIFIC RESEARCH \"\"DEMOKRITOS\"\"\"", "TECHNISCHE UNIVERSITAT DARMSTADT", "UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA", "AMEN TECHNOLOGIES"], "EU_Contribution": ["EUR 580 500"], "Project_Title": ["International Network on Advanced high energy Permanent Magnets"], "Total_Cost": ["EUR 580 500"], "Country": ["Spain", "Greece", "Germany", "Spain", "Greece"], "Project_ACR": ["INAPEM"], "Technology_Description": "The main objective of this Marie Curie RISE action is to improve and exchange interdisciplinary knowledge of materials design by modelling, materials synthesis, characterization, and materials processing for permanent magnet development to be able to provide a critical raw free permanent magnet to the industry. Permanent magnets are indispensable for many commercial and military applications. Major commercial applications include the electric, electronic and automobile industries, communications, information technologies and automatic control engineering. Development and improvement of new technologies based on permanent magnets requires the joint effort of a multidisciplinary researcher collective, involving the expertise of participants on different disciplines including physics, chemistry, materials science and engineering. A consortium with such expertise is put together to undertake an integrative and concerted effort (via knowledge transfer) to provide the fundamental innovations and breakthroughs that are needed to fabricate/implement industrially new phases and microstructures required for the development and application of advanced permanent magnets without the use of critical materials.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-01-01"], "Project_ID": ["691235"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["FORSCHUNGSZENTRUM JULICH GMBH", "INTEL DEUTSCHLAND GMBH", "BAYERISCHE AKADEMIE DER WISSENSCHAFTEN", "BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION", "AURORA SRL", "MEGWARE COMPUTER VERTRIEB UND SERVICE GMBH", "RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG", "EXTOLL GMBH", "THE UNIVERSITY OF EDINBURGH", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.", "KATHOLIEKE UNIVERSITEIT LEUVEN", "STICHTING ASTRON, NETHERLANDS INSTITUTE FOR RADIO ASTRONOMY", "\"ASSOCIATION \"\"NATIONAL CENTRE FOR SUPERCOMPUTING APPLICATIONS\"", "NORGES MILJO-OG BIOVITENSKAPLIGE UNIVERSITET", "HASKOLI ISLANDS", "EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH"], "EU_Contribution": ["EUR 14 998 342"], "Project_Title": ["DEEP - Extreme Scale Technologies"], "Total_Cost": ["EUR 15 873 341,25"], "Country": ["Germany", "Germany", "Germany", "Spain", "Italy", "Germany", "Germany", "Germany", "United Kingdom", "Germany", "Belgium", "Netherlands", "Bulgaria", "Norway", "Iceland", "Switzerland"], "Project_ACR": ["DEEP-EST"], "Technology_Description": "The DEEP-EST (\u201cDEEP - Extreme Scale Technologies\u201d) project will create a first incarnation of the Modular Supercomputer Architecture (MSA) and demonstrate its benefits. In the spirit of the DEEP and DEEP-ER projects, the MSA integrates compute modules with different performance characteristics into a single heterogeneous system. Each module is a parallel, clustered system of potentially large size. A federated network connects the module-specific interconnects. MSA brings substantial benefits for heterogeneous applications/workflows: each part can be run on an exactly matching system, improving time to solution and energy use. This is ideal for supercomputer centres running heterogeneous application mixes (higher throughput and energy efficiency). It also offers valuable flexibility to the compute providers, allowing the set of modules and their respective size to be tailored to actual usage.", "To": ["2020-06-30, ongoing project"], "Meta": [""], "Topic_s": ["FETHPC-01-2016 - Co-design of HPC systems and applications"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2017-07-01"], "Project_ID": ["754304"], "Call_for_Proposal": ["H2020-FETHPC-2016"]}, -{"Partners": ["DUBLIN CITY UNIVERSITY", "LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "\"NATIONAL CENTER FOR SCIENTIFIC RESEARCH \"\"DEMOKRITOS\"\"\"", "CONSIGLIO NAZIONALE DELLE RICERCHE", "USTAV ORGANICKE CHEMIE A BIOCHEMIE, AV CR, V.V.I.", "ATDBIO LIMITED", "BASECLICK GMBH", "LIPINUTRAGEN SRL"], "EU_Contribution": ["EUR 3 556 990,44"], "Project_Title": ["Click Chemistry for Future Gene Therapies to Benefit Citizens, Researchers and Industry"], "Total_Cost": ["EUR 3 556 990,44"], "Country": ["Ireland", "Germany", "United Kingdom", "Greece", "Italy", "Czech Republic", "United Kingdom", "Germany", "Italy"], "Project_ACR": ["ClickGene"], "Technology_Description": "Gene therapy is expected to play a key role in next-generation medicine by correcting the underlying genetic causes of disease, thereby facilitating personalised medicine. Current gene therapy methods possess undesirable side effects, including insertional mutagenesis, toxicity, low efficiency and off-target cutting. Questions also remain regarding the optimal methods for delivering nucleases into cells and tissues. These limitations will be addressed through the original and innovative approach of the ClickGene network. ", "To": ["2018-12-31, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["642023"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Selective ribosome profiling and biochemistry studies on the co-translational protein folding and assembly in eukaryotic protein synthesis"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["srpabsotcpfaaieps"], "Technology_Description": "Biological activity of cells depends on timely production of natively folded proteins by powerful translation and folding machineries. At a critical regulatory intersection of translation and folding, ribosomes act as integration hubs coordinating chaperone, enzyme and membrane targeting factor activity, influencing folding. Final assembly of proteins into oligomeric complexes however, has long been considered post-translational and dependent on random collision of fully synthesized diffusing subunits. In a shift of paradigm, recent evidence from the Bukau laboratory now suggests that in bacteria, assembly initiates co-translationally assisted by chaperones, and gene organization into operons drives co-localized translation of complex subunits that impacts efficiency of assembly. Fundamental differences in eukaryotes such as rarity of operons and differing chaperone constellations imply a widely different folding and assembly biology, which remains largely unexplored. The selective ribosome profiling (SeRP) method, developed by the Bukau lab, now allows ground breaking identification and definition of dynamic interactions of nascent chains, at near-residue resolution. Using SeRP with supporting biochemistry, I will unravel the nascent chain molecular biology underpinning protein folding and assembly in yeast, Saccharomyces cerevisiae, a powerful model for studying the fundamental aspects of this biology. Specifically, I will establish (1) basic features and prevalence of co-translational protein assembly, (2) how chaperones guide co-translational protein folding to affect assembly. Subunit interaction profiles complemented by chaperone interaction profiles, will expose the timing and interplay of protein folding and assembly steps linked to protein synthesis, establishing a detailed conceptually new biology of complex assembly in eukaryotes.", "To": ["2020-04-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-05-01"], "Project_ID": ["753530"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF NEWCASTLE UPON TYNE", "ALCYOMICS LTD", "RISE ACREO AB", "CHR. HANSEN A/S", "DANMARKS TEKNISKE UNIVERSITET", "FUJIFILM DIOSYNTH BIOTECHNOLOGIES UK LIMITED", "LINKOPINGS UNIVERSITET", "SANOFI-AVENTIS DEUTSCHLAND GMBH", "TECHNISCHE UNIVERSITAET BERLIN"], "EU_Contribution": ["EUR 4 038 971,76"], "Project_Title": ["Rapid Bioprocess Development"], "Total_Cost": ["EUR 4 038 971,76"], "Country": ["United Kingdom", "United Kingdom", "Sweden", "Denmark", "Denmark", "United Kingdom", "Sweden", "Germany", "Germany"], "Project_ACR": ["Biorapid"], "Technology_Description": "Reducing lead times of new medicinal drugs to the market by reducing process development and clinical testing timeframes is a critical driver in increasing European (bio)pharmaceutical industry competitiveness. Despite new therapeutic principles (e.g. the use of pluripotent stem cells, regenerative medicine and treatments based on personalised medicine or biosimilars) or regulatory initiatives to enable more efficient production, such as Quality by design (QbD) with associated Process Analytical Technology (PAT) tools , the slow progress in the development of new bioactive compounds still limits the availability of cheap and effective medicines. In addition, the competitiveness of European (bio)pharma industry is impacted by the unavailability of suitably trained personnel. Fundamental changes in the education of scientists have to be realised to address the need for changes in the traditional \u2018big pharma\u2019 business model and the focus on \u2018translational medicine \u2013 more early stage clinical trials with patients, more external innovation and more collaboration\u2019 . These changes in education should be based on combining cutting-edge science from the early stage of product development through to manufacturing with innovation and entrepreneurship as an integral part of the training. The Rapid Bioprocess Development ITN, employing 15 ESRs, brings together industrialist and academic experts with its main aim to address this critical need by developing an effective training framework in rapid development of novel bioactive molecules from the very early stages of potency and efficacy testing to the biomanufacturing process characterisation and effective monitoring. The main focus of the research is on oncology related proteins and recombinant proteins to be used in diabetes treatment, although the resulting monitoring and modelling methods will be applicable to other bioactive molecule process development as demonstrated by validation on a range of relevant bioactives.", "To": ["2018-12-31, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2015-01-01"], "Project_ID": ["643056"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["The role of genome regulation in the origin of animals"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["PREMETAZOAEPIGENOME"], "Technology_Description": "The goal of this proposal is to understand how animals emerged from their unicellular ancestors. It is clear that the role of the genome regulation at the level of chromatin organization plays a crucial role in cell type specification, a hallmark of animals. However, how these genome regulatory mechanisms arose and whether they were already present in the unicellular ancestor of animals remains an open question. So far, there is minimal information to address this question from a comparative point of view. To fill this gap, we will characterize histone modifications, DNA methylation and open chromatin regions in one of the closest unicellular relatives of animals, an ichthyosporean Creolimax fragrantissima, which exhibits a multicellular-like developmental cycle. In particular, we will carry out a comprehensive genome-wide analysis of histone modifications by ChIP-Seq, ATAC-Seq, as well as techniques for detecting the distribution of 6-methyladenosine DNA marks, during the developmental cycle. In parallel, we will also investigate the Myc transcription factor network. Myc, along with its partners Max and Mad have been discovered in unicellular holozoans, suggesting that the network has already regulated cell proliferation and differentiation in the unicellular ancestor of animals. We will detect the genomic targets of Myc, Max and Mad proteins by performing ChIP-Seq. To complement these results with functional studies, we will develop genome editing tools in Creolimax. The data and the comparative analyses will provide significant insights into the nature of the regulatory genome of the last unicellular ancestor of animals. Specifically, we will learn whether the last unicellular ancestor already possessed features of complex genome regulation, such as distal enhancers, gene silencing, and dynamic regulation of chromatin states during development, and to what extent the complexity and function of the Myc transcription factor network was already present.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["747086"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["\u03b2-Lactams as flaviviral NS3 protease inhibitors"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["LIsTEN"], "Technology_Description": "Flaviviral infections already represent a threat to 2.5 billion people living in tropical and sub-tropical regions. As a consequence of climate change and global warming in the near future these infections are expected to spread to areas with moderate climate and the possibility of disease outbreak will exist in Europe, especially around the Mediterranean and Adriatic coast, as well as in the United States of America and large parts of Asia. At the moment no medical treatment against flaviviral diseases is available. Recently, peptide-based compounds which act as flaviviral NS3 protease inhibitors, emerged as potent agents against dengue virus (DENV), Zika virus (ZIKV) and West Nile virus (WNV). These compounds consist of two to four natural or unnatural amino acids and act by binding to the active site of the protease. Accordingly, the incorporation of an electrophilic warhead, a moiety which would facilitate the covalent binding of the inhibitor to the catalytic serine residue, into the peptide inhibitor represents a valuable strategy for the improvement of potency of such inhibitors. The goal of the proposed project is to investigate the potential of \u03b2-lactams as electrophilic warheads in DENV, ZIKV and WNV protease inhibitors. For that purpose, new \u03b2-lactam derivatives will be synthesized, coupled to peptide inhibitors previously developed by the host group and their affinity to the target will be evaluated by biochemical assays. The most potent compounds will be characterized in more detail and their activity against dengue virus replication in cell culture, off-target binding, membrane permeability and metabolic stability will be studied. We expect the formation of a covalent bond between inhibitor and active site of the enzyme to significantly improve inhibitory activity by increasing binding affinity, as well as to ameliorate selectivity and reduce off-target binding.", "To": ["2019-05-01, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-02"], "Project_ID": ["748447"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Ubiquitin-dependent regulation of the microtubule cytoskeleton"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["UBIMAPS"], "Technology_Description": "The microtubule cytoskeleton is a dynamic array of cylindrical polymers that play important roles in various cellular processes including chromosome segregation and ciliogenesis. Hundreds of accessory factors \u2013 grouped under the term microtubule-associated proteins (MAPs) \u2013 orchestrate this network by governing the interaction profile and growth behaviour of microtubules. Due to this critical function, the precise abundance and distribution of MAPs within cells is of high importance and their deregulation is associated with various human diseases, such as ciliopathies and cancer. Surprisingly little is known about mechanisms involved in the regulation of MAPs and so far only a few of them have been identified as targets of the major proteolytic control machinery in cells, i.e. ubiquitin-proteasome system. In this work, I will further explore how MAPs are regulated by ubiquitin-dependent degradation by focussing on a multi-subunit ubiquitin E3 ligase called SCFFbxw5 that seems to play an important role in microtubule control according to preceding experiments of the host lab. Hence, I will investigate in detail two MAPs that were identified as substrates of SCFFbxw5 by the host lab in order to unravel the functional, temporal, and spatial characteristics of their ubiquitylation by SCFFbxw5. Since these MAPs are known to fulfil crucial functions in ciliogenesis and chromosome segregation, this work will promote our knowledge about how ubiquitin-dependent degradation contributes to these processes and may open up novel therapeutic strategies with the associated diseases.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["748315"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG", "RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG"], "EU_Contribution": ["EUR 1 958 101"], "Project_Title": ["Quantum State Assembler"], "Total_Cost": ["EUR 1 958 101"], "Country": ["Germany", "Germany"], "Project_ACR": ["QuStA"], "Technology_Description": "The biggest challenge to using ultracold fermionic atoms to simulate strongly correlated phases is cooling the system to sufficiently low temperatures. The aim of QuStA is to tackle this challenge with a novel bottom-up approach and assemble many-body systems from individually prepared building blocks. This vision has come within reach through recent breakthroughs in our group in preparing and manipulating few-atom systems with unprecedented fidelity. Building on this experience, we will prepare multiple such few-atom systems and develop strategies to merge them adiabatically to form a many-body system.", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["725636"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["\"NATIONAL CENTER FOR SCIENTIFIC RESEARCH \"\"DEMOKRITOS\"\"\""], "EU_Contribution": ["EUR 254 871"], "Project_Title": ["Seismic Moment and Recurrence (SMR) using Luminescence Dating Techniques"], "Total_Cost": ["EUR 254 871"], "Country": ["Greece"], "Project_ACR": ["SMR"], "Technology_Description": "During a seismic-geodynamic process, frictional heating and pressure are generated on sediments fragments resulting in deformation and alteration of minerals contained in them. The luminescence signal enclosed in minerals crystal lattice can be affected and even zeroed during such an event. This has been breakthrough in geochronological studies as it could be utilized as a chronometer for the previous seismic activity of a tectonically active area. Although the employment of luminescence dating has in some cases been successfully described, a comprehensive study outlining and defining protocols for routine luminescence dating applied to neotectonic studies has not been forthcoming. This is due to the fact that the required resetting mechanism of minerals luminescence signal under the influence of friction caused by the relative motion of a fault has been poorly investigated. The proposed project is the experimental investigation, recording and parameterization of the effects of tectonic phenomena on minerals luminescence signal and the development of detailed protocols for the standardization of the luminescence methodology for directly dating deformed geological formations, so that the long-term temporal behaviour of seismically active faults could be reasonably understood and modeled.", "To": ["2020-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Greece"], "Activity": ["Research Organisations"], "From": ["2017-06-01"], "Project_ID": ["743607"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["DUBLIN CITY UNIVERSITY", "INSTITUT BARCELONA D ESTUDIS INTERNACIONALS, FUNDACIO PRIVADA", "KING'S COLLEGE LONDON", "KATHOLIEKE UNIVERSITEIT LEUVEN", "UNIWERSYTET WARSZAWSKI", "RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG", "KIMMAGE DEVELOPMENT STUDIES CENTRE"], "EU_Contribution": ["EUR 3 818 522,52"], "Project_Title": ["Explaining Global India: a multi-sectoral PhD training programme analysing the emergence of India as a global actor"], "Total_Cost": ["EUR 3 818 522,52"], "Country": ["Ireland", "Spain", "United Kingdom", "Belgium", "Poland", "Germany", "Ireland"], "Project_ACR": ["Global India"], "Technology_Description": "The GLOBAL INDIA ETN will deliver a world-class multi-sectoral doctoral training programme focused on India\u2019s emergence as a global and regional power, and its relationship with the EU. International research on India\u2019s global role has not kept pace with the changes to India\u2019s status as a growing economy and significant international actor. This is reflected in the lack of PhD level training programmes in Europe that have a focus on India. Europe lacks a knowledge base on India, the ETN addresses this by creating a multidisciplinary, multi-sectoral network bringing together six leading European universities, with six leading Indian universities, and six non-university partners (one as a beneficiary), all of whom have previously collaborated together. India's actions as a global actor impact on the interests of the EU, and India as a democratic state could potentially be an ally for the EU on international issues that will affect the welfare and security of Europe. The quality of Indian democracy also shapes India\u2019s actions as an international actor and therefore this programme examines the domestic challenges that are shaping Indian democracy and the key international actions of India that are most relevant to its relationship with Europe. The networks training programme is grounded in the academic excellence of the universities and the complimentarily of the strong, diverse range of non-academic partners \u2013 a representative business organisation, a consultancy SME; two think-tanks (in Brussels and New Delhi); a human rights organisation and a global company. The training programme requires that all ESRs will attend 9 network training events, providing workshops on skills (academic and practitioner), with inputs from all partners; complete an internship with a non-academic partner; and conduct extended period of field-work based in an Indian University. Key measurable outputs of the network will be 30 journal articles, 60 policy briefs and an active media presence.", "To": ["2021-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2017-04-01"], "Project_ID": ["722446"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG", "RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG"], "EU_Contribution": ["EUR 1 497 931"], "Project_Title": ["Revealing the electronic energy landscape of multi-layered (opto)electronic devices"], "Total_Cost": ["EUR 1 497 931"], "Country": ["Germany", "Germany"], "Project_ACR": ["ENERGYMAPS"], "Technology_Description": "Modern optoelectronic (OE) devices such as light-emitting or photovoltaic diodes offer exciting opportunities for the future. A wide range of materials has been utilized in these devices, including among others: organic materials, inorganic quantum dots and hybrid perovskites. While the functionality, performance and device physics vary strongly from material to material and device to device, all OE devices depend on the energy levels of their individual components and the interaction of the electronic states at the various heterointerfaces. Lacking a method to map the energy levels in a device, energy level diagrams reported for most devices consist of a combination of individual energy levels for each material, which neglect interactions between the materials (that may cause interfacial dipoles and/or band bending) and do not represent the true energetic landscape. Despite this, they are routinely used for interpretation of device performance and physics.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["714067"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG", "RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG"], "EU_Contribution": ["EUR 2 272 485"], "Project_Title": ["Resolving the molecular mechanisms of intracellular coral-algal symbiosis"], "Total_Cost": ["EUR 2 272 485"], "Country": ["Germany", "Germany"], "Project_ACR": ["SYMCELLS"], "Technology_Description": "Many cells stably integrate microbes to gain ecological advantages for the organism. A remarkable example is the symbiosis between corals and algae, whose provision of photosynthetically fixed nutrients enables coral survival in nutrient-poor habitats. To establish symbiosis, coral cells acquire symbionts via phagocytosis, a process often used for pathogen clearance in other animals. Symbionts reside in phagosomes, and the prevailing view is that, similar to some pathogens, symbionts avoid destruction via phagolysosomal manipulation. Yet, unlike pathogens, symbionts provide nutrients to their host, and this may be key for intracellular persistence. Most research on nutrient translocation has focused on sugars, but surprisingly, sterols may be significant because cnidarians cannot synthesize cholesterol. However, little is known about the underlying molecular mechanisms of symbiosis establishment. Because corals are intractable cell biological models, I will leverage our unique resources and expertise to uncover fundamental aspects of symbiont acquisition and metabolic dependence using the emerging model anemone Aiptasia. To investigate symbiont acquisition (Objective 1), I will distinguish symbiont-phagocytosing cells, test candidate symbiont receptors by gain- and loss-of-function, record symbiont/cell interactions by live-imaging, and generate a symbiosis cell culture system. To understand the significance of symbiont-derived sterols (Objective 2), I will map cellular sterol utilization and identify the sterol transport machinery, test whether symbiont sterols can functionally substitute cholesterol, identify novel sterol-interacting proteins by pull-down assays, and explore symbiont persistence mechanisms using comparative phagosome proteomics. This proposal will for the first time provide a mechanistic understanding of coral-algal symbiosis establishment, a crucial process underpinning coral reefs, economically and ecologically important ecosystems.", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["724715"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG", "RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG"], "EU_Contribution": ["EUR 1 995 250"], "Project_Title": ["Habitability of Oceans and Aqueous Systems on Icy Satellites"], "Total_Cost": ["EUR 1 995 250"], "Country": ["Germany", "Germany"], "Project_ACR": ["Habitat-OASIS"], "Technology_Description": "Icy moons in the outer solar system are prime candidates for harbouring alien life within their sub-surface oceans. Among them Enceladus and Europa are considered to have the largest astrobiological potential. Habitat-OASIS aims to explore the habitability of the ocean worlds of Enceladus, Europa, and other icy satellites using in situ mass spectrometry from on-going and future space missions. At Enceladus (and probably Europa) the ice grains expelled by active plumes carry matter previously dissolved and suspended in the subsurface oceans, allowing constraining their geochemistry. The mass spectrometers aboard the Cassini-Huygens spacecraft currently orbiting Saturn are analysing this material and already delivered spectacular science results. Project 1 of this proposal is the refined data analysis of the Enceladus plume material using novel techniques and is the first ever opportunity to explore in detail a potential ocean habitat outside Earth. Newly developed laser-assisted dispersion experiments will be used to acquire mass spectra on a wide variety of analogue materials, enabling the identification and quantification of inorganic, organic and possibly biogenic compounds embedded in the ice grains. Geochemical aqueous alteration experiments and numerical modelling will support further constraining the habitability of Enceladus and extrapolating the results to other ocean moons. Project 2 will leverage the laboratory capabilities from Project 1 to create a comprehensive library of mass spectra in preparation for the upcoming missions visiting Jupiter\u2019s icy moons: ESA\u2019s JUICE Mission and NASA\u2019s Europa Mission. Even if no plume is present both spacecraft will encounter surface material residing in ejecta clouds around the moons that can be connected to subsurface processes. Having analogue measurements available early in the missions will be critical for exploiting their full potential and will maintain the leading edge of ocean world exploration in Europe.", "To": ["2022-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-02-01"], "Project_ID": ["724908"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG", "RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG"], "EU_Contribution": ["EUR 1 996 000"], "Project_Title": ["Chemically and Thermally Stable Nano-sized Discrete Organic Cage Compounds"], "Total_Cost": ["EUR 1 996 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["CaTs n DOCs"], "Technology_Description": "Shape-persistent organic cage compounds consisting only of covalent bonds are fascinating synthetically targets, because they are studied as hosts for the selective recognition of guest molecules, such as artificial lectins, for catalysis in confined space or for the construction of a new type of porous material. For the latter, the shape-persistency and rigidity of the cage cavity is of utmost importance. There are in principle two existing strategies for the synthesis of shape-persistent organic cage compounds. Strategy I: A stepwise approach by irreversible reactions. Here, the advantage is the chemical stability of the target compound due to the intrinsic stabilities of the formed bonds. The disadvantage of this approach is in general the low overall yield, because the system does not allow any \u2018self-correction\u2019 of once formed bonds. This is different for the other approach used in Strategy II: By using dynamic covalent bond formation as synthetic tool, shape-persistent organic cages can be constructed from rather simple molecular building blocks in one step. Here, the yields are usually very high or even quantitatively, because the reversibility of the reaction allows the system to self-correct. Unfortunately, the resulting compounds are more prone to chemical cleavage of the cages than those synthesized by the irreversible approach.", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["725765"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG", "RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG"], "EU_Contribution": ["EUR 1 659 451"], "Project_Title": ["Galaxy Evolution in the ALMA Era - The Baryon Cycle and Star Formation in Nearby Galaxies"], "Total_Cost": ["EUR 1 659 451"], "Country": ["Germany", "Germany"], "Project_ACR": ["EMPIRE"], "Technology_Description": "A thorough understanding of the processes regulating the conversion of gas into stars is key to understand structure formation in the universe and the evolution of galaxies through cosmic time. Despite significant progress over the past years, the properties of the actual dense, star forming gas across normal disk galaxies remain largely unknown. This will be changed with EMPIRE, a comprehensive 500hr large program led by the PI at the IRAM 30m mm-wave telescope. EMPIRE will provide for the first time extended maps of a suite of dense gas tracers (e.g., HCN, HCO+, HNC) for a sample of nearby, star-forming, disk galaxies.", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["726384"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["WAGENINGEN UNIVERSITY", "WAGENINGEN UNIVERSITY", "UNIVERSITEIT UTRECHT", "RIJKSUNIVERSITEIT GRONINGEN"], "EU_Contribution": ["EUR 2 462 135"], "Project_Title": ["Carbonyl Sulphide: new ways of Observing the Climate System"], "Total_Cost": ["EUR 2 462 135"], "Country": ["Netherlands", "Netherlands", "Netherlands", "Netherlands"], "Project_ACR": ["COS-OCS"], "Technology_Description": "The future climate of our planet strongly depends on the capacity of the biosphere to sequester atmospheric CO2, and on the abundance of stratospheric sulphate aerosols (SSA). These aerosols form a layer that resides at about 16 km altitude that, contrary to CO2, has a cooling effect on climate. These two climate-regulating mechanisms are intricately linked to the atmospheric trace gas carbonyl sulphide (COS).\u00a0", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["742798"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["Institut du Cerveau et de la Moelle \u00e9pini\u00e8re"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Mapping the functional connectome for speed control in spinal motor circuits"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["FunCoSpeedSpine"], "Technology_Description": "The study of spinal circuits underlying locomotion has a rich history, spanning over 100 years of research. Great efforts have been made to map out the connection patterns between motor neurons and different muscle targets. Yet, we know little about how premotor networks govern the recruitment of motor neurons and the control of speed. Recent advances in optogenetics, 3D light patterning and fluorescent-targeted patch clamp recordings of identified neurons now enable to map the functional connectome for speed control in spinal motor circuits. Here we will focus on the role of V2a excitatory premotor interneurons since these cells have the potential to act as a key nexus in the spinal network: i) spanning both in the hindbrain and spinal cord, ii) making direct connections with motor neurons and iii) modulating locomotor speed. Recent studies revealed piecemeal information related to the V2a to motor neurons connection pattern. By taking advantage of the optical clarity of the zebrafish larva, we will implement a comprehensive approach combining in vivo electrophysiology, state-of-the-art 3D optical stimulation of genetically targeted cells and functional calcium imaging to resolve the connectivity map of V2a neurons and answer 3 new key questions:", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2018-02-01"], "Project_ID": ["752199"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ERASMUS UNIVERSITEIT ROTTERDAM", "ERASMUS UNIVERSITEIT ROTTERDAM"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Building EU civil justice: challenges of procedural innovations bridging access to justice"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["EU-JUSTICE"], "Technology_Description": "Civil justice is under pressure. The proclaimed crisis in civil justice results from the ineffectiveness of procedures in terms of the long duration, high costs, and complexity. These undermine access to justice as guaranteed by the Human Rights Convention and the EU Charter of Fundamental Rights. It is illustrative in this regard that 26% of the violation judgments concern undue delay of procedure. A well-functioning civil justice system is pivotal for enforcing rights for consumers and businesses and protecting fundamental rights. Civil justice is also increasingly valued for its contribution to economic growth as seen from the World Bank reports and the EU Justice Agenda for 2020.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["726032"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITE DE NAMUR ASBL", "UNIVERSITE DE NAMUR ASBL"], "EU_Contribution": ["EUR 1 908 375"], "Project_Title": ["Rotifers Highlight the Evolution of Asexuals: the mechanisms of genome evolution in the absence of meiosis"], "Total_Cost": ["EUR 1 908 375"], "Country": ["Belgium", "Belgium"], "Project_ACR": ["RHEA"], "Technology_Description": "Why sexual reproduction is overwhelmingly predominant among the metazoans remains unclear. Ancient asexual taxa are interesting model systems to gain general insights into the adaptive values of sex. The most notorious and the highest taxonomic rank within the metazoans to reproduce asexually is the bdelloid rotifers. While studies suggest that most asexuals arose recently, the published genome of the bdelloid rotifer Adineta vaga provided the first positive evidence for the long-term ameiotic evolution of this group, confirming its ancient asexuality. How bdelloid rotifers have been able to persist despite the expected negative consequences of asexuality is the focus of this ERC proposal. I will study the mechanisms that prevent genome deterioration and promote diversification in the absence of meiotic recombination. I will include sexual rotifer sister clades in the comparison and study all components of the bdelloid lifestyle that may foster their evolution. One of the key components could be their desiccation resistance and the associated DNA double-strand breaks that appear upon prolonged desiccation. To this end, I plan to (i) sequence genomes of sexual rotifers and distinct bdelloid species that diverged a long time ago, including lineages that never experience desiccation; (ii) apply contact genomics, cellular and molecular assays, as well as targeted mutagenesis to uncover their DNA repair mechanisms; (iii) use whole-genome and RAD sequencing to perform a population genomic study of genetic exchanges among bdelloids; and (iv) investigate the function of the meiosis-specific Spo11 gene in bdelloids through targeted mutagenesis and complementation experiments. Using a computational simulation I will generate theoretical predictions on the impact of the mechanisms promoting genome evolution in asexuals. This proposal should revolutionize the field of asexual evolution and provide a new biological model system to study fundamental processes such as DNA repair.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["725998"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION", "FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION"], "EU_Contribution": ["EUR 2 500 000"], "Project_Title": ["Writing, reading and managing stress with H3K9me"], "Total_Cost": ["EUR 2 500 000"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["Epiherigans"], "Technology_Description": "Epigenetic inheritance is the transmission of information, generally in the form of DNA methylation or post-translational modifications on histones that regulate the availability of underlying genetic information for transcription. RNA itself feeds back to contribute to histone modification. Sequence accessibility is both a matter of folding the chromatin fibre to alter access to recognition motifs, and the local concentration of factors needed for efficient transcriptional initiation, elongation, termination or mRNA stability. In heterochromatin we find a subset of regulatory factors in carefully balanced concentrations that are maintained in part by the segregation of active and inactive domains. Histone H3 K9 methylation is key to this compartmentation. ", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-06-01"], "Project_ID": ["743312"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["BRUNEL UNIVERSITY LONDON", "TURKSAT UYDU HABERLESME VE KABLO TV ISLETME AS", "DAVID HOLDING AD", "LK KNOWLEDGE ENGINEERING LTD", "GEBZE TEKNIK UNIVERSITESI"], "EU_Contribution": ["EUR 967 500"], "Project_Title": ["Sustainable energy demand side management for GREEN Data Centers"], "Total_Cost": ["EUR 967 500"], "Country": ["United Kingdom", "Turkey", "Bulgaria", "United Kingdom", "Turkey"], "Project_ACR": ["GREENDC"], "Technology_Description": "The GREENDC proposal contribute to greener data centres by developing a decision support tool that help data centre managers predict energy demands better and evaluate strategies to minimize energy waste and minimize CO2 emissions. GREENDC adopt non-linear energy forecasting model and provide a simulation tool based on dynamic simulation model to allow data centre managers conduct what-if analysis considering factors for energy demands and supply. GREENDC is implemented through knowledge exchange between two academic partners and two industrial partners. Academic partners transfer knowledge on non-linear energy demand forecasting and dynamic simulation to industrial partners while industrial partners transfer their knowledge on data centre operations through secondment activities. The outcome of the GREENDC activities are expected to reduce CO2 emissions and energy waste due to non-optimised energy load balancing from large number of data centres across the Europe.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["734273"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["RIJKSUNIVERSITEIT GRONINGEN", "THE UNIVERSITY OF BIRMINGHAM", "RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG", "OULUN YLIOPISTO", "CHAMBRE DE COMMERCE ET D'INDUSTRIE DE REGION PARIS ILE-DE-FRANCE", "UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II.", "ISTITUTO NAZIONALE DI ASTROFISICA", "INSTITUTO DE ASTROFISICA DE CANARIAS", "UNIVERSITEIT GENT"], "EU_Contribution": ["EUR 3 614 425,92"], "Project_Title": ["SUrvey Network for Deep Imaging Analysis and Learning"], "Total_Cost": ["EUR 3 614 425,92"], "Country": ["Netherlands", "United Kingdom", "Germany", "Finland", "France", "Italy", "Italy", "Spain", "Belgium"], "Project_ACR": ["SUNDIAL"], "Technology_Description": "Though Big Data has become common in many domains nowadays, the challenges to develop efficient and automated mining of the ever increasing data sets by new generations of data scientists are eminent. These challenges span wide swathes of society, business and research. Astronomers with their high-tech observatories are historically at the forefront of this field, but obviously, the impact in e.g. commercial applications, security, environmental monitoring and experimental research is immense. We aim to contribute to this general discussion by training a number of young scientists in the fields of computer science and astronomy, focussing on techniques of automated learning from large quantities of data to answer fundamental questions on the evolution of properties of galaxies. While these techniques will lead to major advances in our understanding of the formation and evolution of galaxies, we will also promote, in collaboration with industry, much more general applications in society, e.g. in medical imaging or remote sensing. We have put together a team of astronomers and computer scientists, from academic and private sector partners, to develop techniques to detect and classify ultra-faint galaxies and galaxy remnants in a deep survey of the Fornax cluster, and use the results to study how galaxies evolve in the dense environment of galaxy clusters. With a team of young researchers we will develop novel computer science algorithms addressing fundamental topics in galaxy formation, such as the huge dark matter fractions inferred by theory, and the lack of detected angular momentum in galaxies. The collaboration is unique - it will develop a platform for deep symbiosis of two radically different strands of approaches: purely data-driven machine learning and specialist approaches based on techniques developed in astronomy. Young scientists trained with such skills are highly demanded both in research and business.", "To": ["2021-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["721463"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "PAUL SCHERRER INSTITUT"], "EU_Contribution": ["EUR 149 997"], "Project_Title": ["Metal Assisted chemical etching of Gratings for X-ray InterferometriC systems"], "Total_Cost": ["EUR 149 997"], "Country": ["Switzerland", "Switzerland", "Switzerland"], "Project_ACR": ["MAGIC"], "Technology_Description": "Phase contrast and scattering-based (dark-field) X-ray imaging can potentially revolutionize the radiological approach to medical imaging because they are intrinsically capable of detecting subtle differences in the electron density of a material and of measuring the effective integrated local small-angle scattering power generated by the microscopic density fluctuations in the specimen. ", "To": ["2018-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2016-11-01"], "Project_ID": ["727246"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["UNIVERSITEIT LEIDEN", "UNIVERSITEIT LEIDEN", "THE UNIVERSITY OF EXETER"], "EU_Contribution": ["EUR 1 444 852"], "Project_Title": ["Reputation Matters in the Regulatory State: Re-thinking the Fundamentals of Regulatory Independence, Credibility and Accountability"], "Total_Cost": ["EUR 1 444 852"], "Country": ["Netherlands", "Netherlands", "United Kingdom"], "Project_ACR": ["RICA"], "Technology_Description": "RICA will fundamentally challenge, reconceptualise and redefine core foundational assumptions of the regulatory state. Arm\u2019s length governance and regulatory independence have become the cornerstone normative and institutional design principles of the European regulatory state. Regulatory credibility is premised on agency insulation from politics with major systemic implications in the form of a rise in non-majoritarianism and a parallel devaluation of the political process. Efforts to compensate through alternative sources of input legitimacy have proven challenging. Conceptualised in a rational-choice tradition, accountability is seen to be in a zero-sum relationship with regulatory autonomy. Bolstering accountability is said to threaten autonomy, undermining the system\u2019s normative foundations.", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["716439"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG", "RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG"], "EU_Contribution": ["EUR 1 499 629"], "Project_Title": ["Multi-scale Star Formation Across Nascent Galaxies"], "Total_Cost": ["EUR 1 499 629"], "Country": ["Germany", "Germany"], "Project_ACR": ["MUSTANG"], "Technology_Description": "One of the fundamental questions in modern astrophysics is how gas is converted into stars during galaxy formation, and how this may have changed with galactic environment and cosmic time. It is widely accepted that the unknown physics of star formation (SF) in molecular clouds and feedback from massive stars represent the main uncertainties in our understanding of galaxy formation. The key open questions are: which physical mechanisms govern the time-evolution of gas towards SF and its subsequent expulsion by feedback? How do these physics change with environment or cosmic time? How did the most extreme stellar systems in the Universe (i.e. globular clusters) form at high redshift? How do the cloud-scale physics of SF and feedback connect cold dark matter cosmology to the observable galaxy population? It is now possible to answer these questions thanks to two crucial developments. (1) The latest generation of billion-euro observatories allow the necessary observational data to be taken. (2) The techniques needed to solve the problem have been developed, tested, and validated, through major theoretical efforts that I have led. These developments position me ideally to answer the above questions with a unique combination of world-leading observational data, fundamental theory, innovative analysis techniques, and state-of-the-art simulations. I will use these to formulate a multi-scale description of SF and feedback, focussing on the cloud-scale physics and advancing the field beyond the phenomenology of galactic scaling relations. I will introduce an empirically-motivated, physical model for cloud-scale SF and feedback in galaxy formation simulations, thereby overcoming their main limitation and making the crucial step of linking the observable galaxy population to cold dark matter cosmology. This ambitious programme bridges observations, theory, and simulations, and can only be realised with the human resources provided by an ERC Starting Grant.", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["714907"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["KAROLINSKA INSTITUTET"], "EU_Contribution": ["EUR 265 059"], "Project_Title": ["Identifying the neuronal basis of self-concept in the human medial prefrontal and medial temporal brain regions"], "Total_Cost": ["EUR 265 059"], "Country": ["Sweden"], "Project_ACR": ["SELFIEv2.0"], "Technology_Description": "Humans have a remarkable ability to construct a complex conceptual representation of their own identity and personality. This self-concept plays a crucial role in everyday life; however, its neurobiological basis remains unknown. Here, we will use the state-of-the-art method of intracranial electroencephalography (iEEG) to characterize the neuronal representation of self-concept at the level of single-neurons in the medial prefrontal and medial temporal brain regions. IEEG will be recorded from awake human subjects, which is possible because a subset of neurosurgical patients requires placement of intracranial electrodes to identify the focus of epileptic seizures. We will conduct our studies during this monitoring time, with no added risk to the patients. Our data will provide unprecedented insights into the neuronal basis of the human self. Our findings will be of great interest to scientists in a broad range of disciplines, including neuroscience, psychology, artificial intelligence, neurology, psychiatry, as well as to the general public. The supervisors are world-leading experts in the neural self-representation (Prof. Ehrsson) and iEEG (Prof. Fried). Their laboratories conduct excellent research, as documented by multiple high-impact publications. The host institution (Karolinska Institute) and the partner institution (University of California, Los Angeles) are among the best universities in the world. Together, the fellowship provides an exceptional opportunity for the experienced researcher to become a leader in his field; he will learn the unique method of iEEG and he will collect the very first data on the neuronal basis of the conceptual self.", "To": ["2021-02-28, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["750955"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["The vision-strike conversion: Neural control of the predatory strike behavior in stomatopods"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["EYEPOD"], "Technology_Description": "Controlling how the body is propelled through space is paramount for survival of most animals. Many species, including humans, use feedback from their visual and proprioceptive systems to correct or confirm body movements. However, feedback is limited to events that form part of the past. For many high performance behaviors, such as catching a fast incoming ball, the appropriate movement must be 1. anticipated from a short observation period and 2. actuated without sensory feedback. ", "To": ["2018-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-08-01"], "Project_ID": ["702238"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 212 194,80"], "Project_Title": ["Wildcat Economics: Informal Mining and Gold from the Global Margins in Contemporary Latin America"], "Total_Cost": ["EUR 212 194,80"], "Country": ["Denmark"], "Project_ACR": ["WILDCAT"], "Technology_Description": "The proposed project will conduct an ethnographic study of small-scale gold mining in South America, otherwise known as \u2018wildcat mining\u2019, and aims to explore the interconnection between formal and informal economic spheres at the global margins. The project will forge a concept of \u2018wildcat economics\u2019: that is, the particular form of small-scale mining that takes place in extremely remote regions of the world essentially \u2018under the radar\u2019, in this case the Amazonian rainforest. As such, WILDCAT will explore forms of globalization that do not comprise direct corporate growth, but emerge from individual ventures, and thus challenges stereotypical renditions of resource extraction and global capitalism. Through this analytical framework, the project provides insights into lesser-understood workings of globalization by offering new ways of conceptualizing the jurisdictions of global capitalism and the economic activities that lie beyond its limits. Fieldwork will take place in the Madre de Dios region of Peru where wildcat mining activity is clustered, and will draw on methodologies of both anthropology and geography. I will significantly benefit from a placement at the University of Copenhagen as it is one of the key European centers for the study of Resource Extraction and Management. Significantly, Copenhagen University houses the Centre for Sustainable Artisanal and Small-Scale Mining (SASMin), which explores the activities and issues associated with small-scale mining around the world. I will be affiliated with this centre as a researcher representing and bringing insights from the discipline of anthropology.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["748303"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["BAYERISCHE JULIUS-MAXIMILIANS UNIVERSITAT WURZBURG", "BAYERISCHE JULIUS-MAXIMILIANS UNIVERSITAT WURZBURG"], "EU_Contribution": ["EUR 2 497 567"], "Project_Title": ["Four experiments in Topological Superconductivity."], "Total_Cost": ["EUR 2 497 567"], "Country": ["Germany", "Germany"], "Project_ACR": ["4-TOPS"], "Technology_Description": "Topological materials have developed rapidly in recent years, with my previous ERC-AG project 3-TOP playing a major role in this development. While so far no bulk topological superconductor has been unambiguously demonstrated, their properties can be studied in a very flexible manner by inducing superconductivity through the proximity effect into the surface or edge states of a topological insulator. In 4-TOPS we will explore the possibilities of this approach in full, and conduct a thorough study of induced superconductivity in both two and three dimensional HgTe based topological insulators. The 4 avenues we will follow are:", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["741734"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 2 492 565"], "Project_Title": ["Climate Dynamics of Exoplanets with Condensible Atmospheres"], "Total_Cost": ["EUR 2 492 565"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["EXOCONDENSE"], "Technology_Description": "Condensible substances, which undergo a phase change from gaseous to liquid or solid condensed form, have a profound impact on planetary atmospheres, and are central to the determination of most key aspects of a planet's climate. The three phases of water operating in Earth's present climate provide the archetype for condensible processes in climate dynamics, but the dawning age of exoplanet discovery and characterization requires that the understanding of phase change effects be expanded far beyond the situations familiar from the study of Earth's climate, or indeed of the climate of any Solar System planet. The goal of this project is to pioneer the advances needed to understand condensible climate dynamics for the vastly broader range of condensible substances, thermodynamic and planetary configurations presented by the growing catalogue of exoplanets. The emphasis will be on the smaller range of planets (super-Earth to Earth mass or size class), which need not have hydrogen-dominated atmospheres and therefore present a richer and highly challenging variety of possible condensible behavior. This class of planets includes all planets that are potentially habitable for Earthlike life, but even planets that are far from habitable shed light on essential features of planets in the Universe, and will be studied. The work will embrace both small scale buoyancy-driven turbulent convection and planetary scale circulations. Idealized numerical simulations, buttressed by theoretical analysis will be employed. Particular emphasis will be put on aspects of exoclimate that are amenable to probing by current observations and improved observational techniques likely to become available in the coming decade. Such properties include cloud properties observable through transit-depth spectra and dayside/nightside temperature and composition contrasts observable through phase curve observations.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["740963"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 999 920"], "Project_Title": ["Structure and Function of the Bacterial Transformasome"], "Total_Cost": ["EUR 1 999 920"], "Country": ["France", "France"], "Project_ACR": ["TransfoPneumo"], "Technology_Description": "Natural genetic transformation, first discovered in Streptococcus pneumoniae by Griffith in 1928, is observed in many Gram-negative and Gram-positive bacteria. This process promotes genome plasticity and adaptability. In particular, it enables many human pathogens such as Streptococcus pneumoniae, Staphylococcus aureus or Neisseria gonorrhoeae to acquire resistance to antibiotics and/or to escape vaccines. For natural transformation to occur, bacteria must develop a highly regulated physiological state called competence, during which a multiprotein machinery, designated as the transformasome, is specifically expressed. The transformasome drives the uptake of extracellular DNA and its subsequent integration into the bacterial genome. This intricate system can be divided into three functional entities: the transformation pilus, the DNA entry pore and the recombination apparatus. The architecture and function of the transformasome remains largely elusive. We propose to dissect the structure and function of this system in the human pathogen Streptococcus pneumoniae. We will combine four complementary approaches to attain our goal: (1) Molecular biology and biochemical studies in vitro (2) Structural biology on purified proteins or protein complexes using X-ray crystallography and cryo-electron microscopy (3) Structure-function studies in vitro and in vivo (4) Structural biology in situ using cryo-tomography.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["725554"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITEIT UTRECHT", "RIJKSUNIVERSITEIT GRONINGEN", "WAGENINGEN UNIVERSITY", "UNIVERSITE DE VERSAILLES SAINT-QUENTIN-EN-YVELINES.", "EIDGENOSSISCHE MATERIALPRUFUNGS- UND FORSCHUNGSANSTALT", "ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE", "RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG", "AKADEMIA GORNICZO-HUTNICZA IM. STANISLAWA STASZICA W KRAKOWIE", "LUNDS UNIVERSITET"], "EU_Contribution": ["EUR 3 361 290,84"], "Project_Title": ["MEthane goes MObile - MEasurements and MOdelling"], "Total_Cost": ["EUR 3 361 290,84"], "Country": ["Netherlands", "Netherlands", "Netherlands", "France", "Switzerland", "United Kingdom", "Germany", "Poland", "Sweden"], "Project_ACR": ["MEMO2"], "Technology_Description": "Mitigation of climate change is a key scientific and societal challenge and also a headline target of the EU2020 strategy. Strong reductions in greenhouse gas emissions are necessary to reach the global warming target agreed on at the 2015 United Nations Convention of Parties in Paris. Such emission reductions can only be achieved if sources are properly quantified and mitigation efforts are verified, but there are large discrepancies between official emission inventories and estimates derived from direct measurement of the air.", "To": ["2021-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-03-01"], "Project_ID": ["722479"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["IMPACT OF AROMA AND AROMA INTERACTIONS ON SWEET FLAVOR PERCEPTION IN JUICES AND SOFT BEVERAGES"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["FLAVODRINKS"], "Technology_Description": "In efforts to help consumers improve their health by reducing their consumption of sugar, salt and fat (Europea 2006/1924/EU), the European Commission recently set new standards for the formulation, production, labeling and advertising of fruit juices (Europea 2012/12/EU). Similar regulations are expected soon for soft drinks. Soft drinks have begun to suffer a poor public image because of their high content of sugar or sugar substitutes, which the beverage industry uses to counteract or mask undesirable flavors. It may be possible to avoid the need to add sugar to fruit juices and soft drinks if we can identify aroma compounds that help the consumer perceive a drink as sweet. Understanding the interaction between aromas allow act on sweetness perceived by the consumer and get drinks with less sugar added.", "To": ["2017-05-31, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2015-06-01"], "Project_ID": ["655545"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["ISTITUTO NAZIONALE DI ASTROFISICA", "REGENTS OF UNIVERSITY OF MINNESOTA"], "EU_Contribution": ["EUR 244 269"], "Project_Title": ["Cosmological simulations of radio bright plasmas"], "Total_Cost": ["EUR 244 269"], "Country": ["Italy", "United States"], "Project_ACR": ["Cosmo Plasmas"], "Technology_Description": "Merging galaxy clusters are among the most energetic events in the Universe. Their interaction generates shocks and turbulence in the ionised cluster medium, driving the amplification of magnetic fields and the acceleration of relativistic particles. This leads to the formation of large diffuse radio sources in some clusters. The next generation of radio telescopes, including the European LOFAR observatory, will revolutionize the field, unveiling a complex picture of these non-thermal processes in clusters. However we still lack numerical simulations to match the capabilities of these instruments. This roots in the complexity of models for MHD-turbulence and cosmic-rays poses challenging demands to simulators. Only recent advances in implementations at the outgoing host and by the applicant make these simulations now feasible.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["658912"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["HERIOT-WATT UNIVERSITY", "CENTRE TECNOLOGIC DE TELECOMUNICACIONS DE CATALUNYA", "GEORGIA INSTITUTE OF TECHNOLOGY"], "EU_Contribution": ["EUR 257 191,20"], "Project_Title": ["Inkjet-Printed Wireless Powered Circuits for Sensing and Identification."], "Total_Cost": ["EUR 269 857,80"], "Country": ["United Kingdom", "Spain", "United States"], "Project_ACR": ["iREACT"], "Technology_Description": "The project establishes the application of inkjet printing as a key technology for the implementation of batteryless and wireless sensor and communication circuits based on wireless power transfer and energy harvesting, enabling the realization of the Internet of Things (IoT). Inkjet printing supports a large volume production, achieves a good resolution necessary for high frequency electronics, enables the use of a variety of low cost and flexible materials, and is a direct-write, and additive manufacturing technology. The research outcomes of the project focus in two goals, 1) demonstrate low profile, conformal, inkjet printed RF energy harvesters and autonomous wireless sensor and communication circuits, and 2) establish inkjet printing in millimeter wave frequencies. ", "To": ["2019-02-10, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2016-02-11"], "Project_ID": ["661621"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITY OF BRADFORD", "UNIVERSITY OF BRADFORD", "THE UNIVERSITY OF WARWICK", "THE UNIVERSITY OF BIRMINGHAM", "THE UNIVERSITY OF NOTTINGHAM", "THE UNIVERSITY OF NOTTINGHAM NINGBO"], "EU_Contribution": ["EUR 2 497 843"], "Project_Title": ["Europe\u2019s Lost Frontiers: exploring climate change, settlement and colonisation of the submerged landscapes of the North Sea basin using ancient DNA, seismic mapping and complex systems modelling"], "Total_Cost": ["EUR 2 497 843"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom", "United Kingdom", "United Kingdom", "China"], "Project_ACR": ["Lost Frontiers"], "Technology_Description": "The only lands on Earth that have not been explored in any depth by science are those that have been lost to the oceans. Global warming at the end of the last Ice Age led to the inundation of vast landscapes that had once been home to thousands of people. These lost lands hold a unique and largely unexplored record of settlement and colonisation linked to climate change over millennia. Amongst the most significant is Doggerland. ", "To": ["2020-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-12-01"], "Project_ID": ["670518"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["CONSIGLIO NAZIONALE DELLE RICERCHE", "PARIS-LODRON-UNIVERSITAT SALZBURG", "UNIVERSITA DEGLI STUDI DI GENOVA", "MIKROBIOLOGICKY USTAV - AVCR, V.V.I.", "EBERHARD KARLS UNIVERSITAET TUEBINGEN", "UNIVERZA V LJUBLJANI", "CARDIFF UNIVERSITY", "NATURAL ENVIRONMENT RESEARCH COUNCIL", "AvantiCell Science Ltd", "FUNDACIO INSTITUT CATALA DE NANOCIENCIA I NANOTECNOLOGIA"], "EU_Contribution": ["EUR 2 814 491,16"], "Project_Title": ["Probing safety of nano-objects by defining immune responses of environmental organisms"], "Total_Cost": ["EUR 2 814 491,16"], "Country": ["Italy", "Austria", "Italy", "Czech Republic", "Germany", "Slovenia", "United Kingdom", "United Kingdom", "United Kingdom", "Spain"], "Project_ACR": ["PANDORA"], "Technology_Description": "PANDORA (Probing safety of nano-objects by defining immune responses of environmental organisms) shall assess the global impact of engineered nanoparticles (NP) on the immune responses of representative organisms covering all evolutionary stages and hierarchical levels from plants to invertebrates and vertebrates. Immunity is a major determinant of the survival and fitness of all living organisms, therefore immunosafety of engineered NP is a key element of environmental nanosafety. PANDORA will tackle the issue of global immunological nanosafety by comparing the impact of widely-used NP (e.g., iron, titanium and cerium oxide) on the human immune response with their effects in representative terrestrial and marine organisms. This comparison will focus on the conserved system of innate immunity/stress response/inflammation, aiming to identify common mechanisms and markers across immune defence evolution shared by plants (Arabidopsis), invertebrate (bivalves, echinoderms, earthworms), and vertebrate (human) species. ", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations"], "From": ["2016-01-01"], "Project_ID": ["671881"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH", "INFRAFRONTIER GMBH", "CENTRE EUROPEEN DE RECHERCHE EN BIOLOGIE ET MEDECINE", "MEDICAL RESEARCH COUNCIL", "USTAV MOLEKULARNI GENETIKY AKADEMIE VED CESKE REPUBLIKY VEREJNA VYZKUMNA INSTITUCE", "Toronto Centre for Phenogenomics Inc.", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "GENOME RESEARCH LIMITED", "CONSIGLIO NAZIONALE DELLE RICERCHE", "UNIVERSITAT AUTONOMA DE BARCELONA", "EUROPEAN MOLECULAR BIOLOGY LABORATORY"], "EU_Contribution": ["EUR 1 103 613,75"], "Project_Title": ["Research Infrastructures for Phenotyping, Archiving and Distribution of Mouse Disease Models - Promoting International Cooperation and User Engagement to Enhance Biomedical Innovation"], "Total_Cost": ["EUR 1 109 863,75"], "Country": ["Germany", "Germany", "France", "United Kingdom", "Czech Republic", "Canada", "Spain", "United Kingdom", "Italy", "Spain", "Germany"], "Project_ACR": ["IPAD-MD"], "Technology_Description": "The IPAD-MD project addresses cooperation and coordination between the pan-European INFRAFRONTIER Research Infrastructure and complementary research infrastructures in America, Asia and Australia, contributing to the global effort of the International Mouse Phenotyping Consortium (IMPC). In order to increase the reach of INFRAFRONTIER, IPAD-MD will also reach out to complementary infrastructures and user communities in Africa. ", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["INFRASUPP-6-2014 - International cooperation for research infrastructures"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Other", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-06-01"], "Project_ID": ["653961"], "Call_for_Proposal": ["H2020-INFRASUPP-2014-2"]}, -{"Partners": ["LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN", "STICHTING KATHOLIEKE UNIVERSITEIT", "ROCHE DIAGNOSTICS GMBH", "THE NOTTINGHAM TRENT UNIVERSITY", "ISTITUTO EUROPEO DI ONCOLOGIA SRL", "MEDIZINISCHE UNIVERSITAT INNSBRUCK", "FUNDACION CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III", "REGION HOVEDSTADEN", "INSTITUT GUSTAVE ROUSSY"], "EU_Contribution": ["EUR 3 627 525,24"], "Project_Title": ["Training Network for the Immunotherapy of Cancer"], "Total_Cost": ["EUR 3 627 525,24"], "Country": ["Germany", "Netherlands", "Germany", "United Kingdom", "Italy", "Austria", "Spain", "Denmark", "France"], "Project_ACR": ["IMMUTRAIN"], "Technology_Description": "In the European Union, cancer is the leading cause of death and the overall cancer incidence is still increasing. As a result of expanding efforts to improve cancer outcome, a main paradigm change is occurring in cancer therapy towards individualized medicine. Antibody-based therapies form an integral and constantly growing part of this approach. Antibody-based therapies will strongly influence the coming decade of cancer care. The importance of immunotherapy has been highlighted by the prestigious Science journal as \u201cbreakthrough of the year 2013\u201d, heralding the rising importance of immunotherapy. Accordingly the need for well-trained and skilled researchers in academia and industry is dramatically increasing in this field. IMMUTRAIN is a training network bringing together experts in the fields of monoclonal antibodies, dendritic cells, T-cells and immunomodulatory nucleic acids with a considerable industrial involvement. The network comprises nine academic research groups and five industrial partners in a total of seven European countries. IMMUTRAIN will actively create synergies between those sectors by forming and promoting young researchers to match the challenges of immunotherapies. Particular focus will be placed on combinatorial therapies and on the new emerging field of bispecific antibodies used to target both the tumor and the patient\u00b4s immune system. Fifteen Ph. D. students (early stage researchers, ESR) reinforced by the project leaders will investigate innovative therapeutic strategies and provide the rationale for future clinical trials. Throughout their projects, ESR will learn to integrate academic and industrial aspects and will sharpen their experimental and complementary skills in a well-designed and diversified training program.", "To": ["2019-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations"], "From": ["2015-12-01"], "Project_ID": ["641549"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["NATIONAL OBSERVATORY OF ATHENS"], "EU_Contribution": ["EUR 152 653,20"], "Project_Title": ["Cyclone processes leading to extreme rainfall in the Mediterranean region"], "Total_Cost": ["EUR 152 653,20"], "Country": ["Greece"], "Project_ACR": ["ExMeCy"], "Technology_Description": "Mediterranean cyclones are among the most important natural hazards in the region, affecting more than 135 million people. The physical mechanisms that make Mediterranean cyclones evolve into severe storms are not yet fully understood due to many uncertainties in the underlying atmospheric processes. These processes are mainly associated with deep convection and air-sea interactions at meso-scales, as well as with large-scale atmospheric systems that affect the region. The scientific objective of the project is to show how these processes lead to extreme rainfall in the Mediterranean and contribute to the better forecasting of cyclones induced extreme rainfall.", "To": ["2018-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Greece"], "Activity": ["Research Organisations"], "From": ["2016-05-01"], "Project_ID": ["658997"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["BIOBANKS AND BIOMOLECULAR RESOURCES RESEARCH INFRASTRUCTURE CONSORTIUM (BBMRI-ERIC)", "EUROPEAN MOLECULAR BIOLOGY LABORATORY", "MEDIZINISCHE UNIVERSITAET WIEN", "INFRAFRONTIER GMBH", "EATRIS ERIC", "ECRIN EUROPEAN CLINICAL RESEARCH INFRASTRUCTURE NETWORK", "UNIVERSIDADE DO MINHO", "USTAV MOLEKULARNI GENETIKY AKADEMIE VED CESKE REPUBLIKY VEREJNA VYZKUMNA INSTITUCE", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "EUROPEAN RESEARCH INFRASTRUCTURE CONSORTIUM FOR THE SURVEY OF HEALTH, AGEING AND RETIREMENT IN EUROPE"], "EU_Contribution": ["EUR 1 995 633,75"], "Project_Title": ["Reseach Infrastructures Training Programme"], "Total_Cost": ["EUR 1 995 633,75"], "Country": ["Austria", "Germany", "Austria", "Germany", "Netherlands", "France", "Portugal", "Czech Republic", "United Kingdom", "Italy", "France", "Germany"], "Project_ACR": ["RItrain"], "Technology_Description": "There has never been a greater need for skilled managers and operators of research infrastructure (RI). Europe must develop the workforce that will turn ~50 nascent RIs with sites in different countries into powerhouses of support for major projects comparable to understanding the blueprint of life or discovering new subatomic particles. RItrain will develop a flagship training programme enabling RIs across all domains to gain expertise on governance, organisation, financial and staff management, funding, IP, service provision and outreach in an international context. It will be designed and delivered by experts who have set up and managed RIs from concept to maturity. We will define competencies required by RIs through consultation with their senior managers. The resulting competency framework will underpin a Bologna-compliant degree, the Master in Research Infrastructure Management, with three delivery routes. (1) Professionals working in RIs (or organisations representing them) can dip into the content, focusing on areas where there is most need. (2) Management teams can take the course as an organisation, dividing modules between them to gain a certificate for the RI. This will flag the RI as an organisation that values staff development, improving its attractiveness as an employer. (3) Recent graduates and others wishing to enhance their employability can take a full master\u2019s degree. Course content will include webinars led by senior managers of RIs. A staff-exchange programme will catalyse exchange of best practice and foster cooperation to develop a mobile work force effective across many RIs. By the end of the project we will be delivering a master\u2019s curriculum funded through course fees. Others with an interest in adopting it will be encouraged to do so, providing a means of expanding the programme. Europe\u2019s research community and global collaborators will gain from world-class facilities to support excellent, high-impact research to benefit humankind.", "To": ["2019-08-31, ongoing project |"], "Meta": [""], "Topic_s": ["INFRASUPP-3-2014 - Strengthening the human capital of research infrastructures"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Austria"], "Activity": ["Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Other", "Research Organisations", "Other", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations"], "From": ["2015-09-01"], "Project_ID": ["654156"], "Call_for_Proposal": ["H2020-INFRASUPP-2014-2"]}, -{"Partners": ["EBERHARD KARLS UNIVERSITAET TUEBINGEN", "EBERHARD KARLS UNIVERSITAET TUEBINGEN"], "EU_Contribution": ["EUR 1 498 353"], "Project_Title": ["From the origin of Earth's volatiles to atmospheric oxygenation"], "Total_Cost": ["EUR 1 498 353"], "Country": ["Germany", "Germany"], "Project_ACR": ["O2RIGIN"], "Technology_Description": "Aim of this project is to understand the connection between endogenic and exogenic processes of our planet that led to the redox contrast between Earth\u2019s surface and interior. For this purpose the time constraints on atmospheric oxygenation can be refined and for the first time linked with a new approach to Earth\u2019s endogenic processes like plate tectonics, mantle melting, volcanism, continent formation and subduction-related sediment- and crust recycling. These objectives will be achieved by using the unique geochemical capabilities of the selenium (Se) isotope system to unlock the geological record of changing oxygen fugacities in the mantle-crust-atmosphere reservoirs. The power of the Se isotope system lies in its redox sensitivity and in the volatile and highly siderophile/chalcophile character of elemental Se. This links Se to the evolution of other volatiles during key geological processes from Earth formation ca. 4.5 Ga ago until today. The occurrence and behavior of Se is fully controlled by accessory micrometric sulfide minerals in the silicate Earth, which may conserve their original Se isotopic signatures over large geological timescales and can be dated via the 187Re-187Os geochronometer. This offers high resolutions in time and space that are groundbreaking for research on Earth System Oxygenation. Covering Earth geologic history, new high-precision Se isotope data of the sedimentary and representative mantle-derived magmatic rock record from all major plate tectonic settings will be combined with the mineral-scale record of robust and global \u201ctime capsules\u201d such as diamond inclusions. Once the evolution into todays dynamic Earth\u2019s Redox System is understood, the investigation will be pushed back in time to Earth\u2019s formation. This involves a reconciliation of the meteoritic and Archean rock and mineral-scale Se isotope record to constrain the origin of volatiles essential for the oceans, generation of an atmosphere and development of life on our planet.", "To": ["2020-02-29, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-03-01"], "Project_ID": ["636808"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["KARLSRUHER INSTITUT FUER TECHNOLOGIE", "INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE TOULOUSE INSAT", "ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA", "PANEPISTIMIO THESSALIAS", "UNIVERSITE D'AIX MARSEILLE", "UNIVERSITY OF LIMERICK", "Institute of Mechanics, Bulgarian Academy of Sciences", "MITIS", "Alcatel Lucent Ireland Limited", "IN'AIR SOLUTIONS"], "EU_Contribution": ["EUR 3 815 117,07"], "Project_Title": ["Research and training network on MIniaturized Gas flow for Applications with enhanced Thermal Effects"], "Total_Cost": ["EUR 3 815 117,07"], "Country": ["Germany", "France", "Italy", "Greece", "France", "Ireland", "Bulgaria", "Belgium", "Ireland", "France"], "Project_ACR": ["MIGRATE"], "Technology_Description": "Depletion of natural resources combined with the extending footprint of mankind has led to a shift in importance of research and development topics. In the 1970s and 1980s process yield was primarily targeted, but emphasis is now focussed on resource efficiency as a primary objective. Routes for resource efficiency have to be identified and implemented to provide a more environmental and resource-oriented technology in near future. ", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-11-01"], "Project_ID": ["643095"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN", "LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN", "EBERHARD KARLS UNIVERSITAET TUEBINGEN"], "EU_Contribution": ["EUR 1 499 125"], "Project_Title": ["Transformations of Food in the Eastern Mediterranean Late Bronze Age"], "Total_Cost": ["EUR 1 499 125"], "Country": ["Germany", "Germany", "Germany"], "Project_ACR": ["FoodTransforms"], "Technology_Description": "Mediterranean cuisine has long been perceived as a timeless constant, already linking the different societies around the sea by the 2nd mill. BC. The geographic frame was considered to be essential, whereas intercultural entanglements as transformative factors were neglected. By integrating archaeological, textual and scientific research, we will shed new light on the transformative power of cultural encounters arising from the intense connectivity between local communities in the Eastern Mediterranean Late Bronze Age and the simultaneous introduction of food of South and East Asian origin (e.g. pepper, nutmeg, cinnamon). We intend to achieve this goal by analysing human remains and pottery vessels from selected sites between the Aegean and Egypt from the 15th to the 12th cent. BC to trace spatial and temporal dynamics. Organic residue analyses of the pottery will shed light on the preparation and consumption of food (e.g. oils, wine, spices). We will include vessels with their contents labelled on them and then link so-far hardly understood Egyptian textual evidence to the contents, which enables a new understanding of these texts for the study of food. We combine the results from residue analyses with a cutting-edge approach to the study of human dental calculus, the potential of which has just been recognized for the understanding of human nutrition: we will analyse DNA from food traces and bacteria as well as proteins, lipids and microremains in dental calculus. This will give unique insight into individual consumption of different oils (olive, sesame etc.), kinds of milk (cow, sheep, goat) and related products (cheese, kefir) and of plants (spices, cereals), which goes far beyond what has been achieved to date. The linkage of food residues in vessels and calculus will allow us to trace processes of homogenization and diversification as consequences of early globalization and better understand food circulation in present and future globalization processes.", "To": ["2021-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-07-01"], "Project_ID": ["678901"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["EOTVOS LORAND TUDOMANYEGYETEM", "EOTVOS LORAND TUDOMANYEGYETEM"], "EU_Contribution": ["EUR 1 511 436"], "Project_Title": ["Astrophysical Dynamics and Statistical Physics of Galactic Nuclei"], "Total_Cost": ["EUR 1 511 436"], "Country": ["Hungary", "Hungary"], "Project_ACR": ["GalNUC"], "Technology_Description": "We address some of the major unsolved questions of galactic nuclei using methods of condensed matter physics. Galactic nuclei host a central supermassive black hole, a dense population of stars and compact objects, and in many cases a bright gaseous disk feeding the supermassive black hole. The observed stellar distribution exhibits both spherical and counterrotating disk-like structures. Existing theoretical models cannot convincingly explain the origin of the stellar disks. Is there also a \u201cdark cusp\u201d or \u201cdark disk\u201d of stellar mass black holes? Are there intermediate mass black holes in the Galactic center? We examine the statistical physics of galactic nuclei and their long term dynamical evolution. A star orbiting a supermassive black hole on an eccentric precessing orbit covers an axisymmetric annulus. The long-term gravitational interaction between such annuli is similar to the Coulomb interaction between axisymmetric molecules constituting a liquid crystal. We apply standard methods of condensed matter physics to examine these astrophysical systems. The observed disk and spherical structures represent isotropic-nematic phase transitions. We derive the phase space distribution and time-evolution of different stellar components including a population of black holes. Further, we investigate the interaction of a stellar cluster with a gaseous disk, if present. This leads to the formation of gaps, warps, and spiral waves in the disk, the redistribution of stellar objects, and possibly the formation of intermediate mass black holes. We explore the implications for electromagnetic and gravitational wave observatories. Dark disks of black holes could provide the most frequent source of gravitational waves for LIGO and VIRGO. These detectors will open a new window on the Universe; the proposed project will open a new field in gravitational wave astrophysics to interpret the sources. We also explore implications for electromagnetic observations.", "To": ["2020-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Hungary"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-08-01"], "Project_ID": ["638435"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET", "KOBENHAVNS UNIVERSITET", "REGION HOVEDSTADEN"], "EU_Contribution": ["EUR 2 500 000"], "Project_Title": ["Reaching the effects of gastric bypass on diabetes and obesity without surgery"], "Total_Cost": ["EUR 2 500 000"], "Country": ["Denmark", "Denmark", "Denmark"], "Project_ACR": ["BYPASSWITHOUTSURGERY"], "Technology_Description": "Gastric bypass surgery results in massive weight loss and diabetes remission. The effect is superior to intensive medical treatment, showing that there are mechanisms within the body that can cure diabetes and obesity. Revealing the nature of these mechanisms could lead to new, cost-efficient, similarly effective, non-invasive treatments of these conditions. The hypothesis is that hyper-secretion of a number of gut hormones mediates the effect of surgery, as indicated by a series of our recent studies, demonstrating that hypersecretion of GLP-1, a hormone discovered in my laboratory and basis for the antidiabetic medication of millions of patients, is essential for the improved insulin secretion and glucose tolerance. But what are the mechanisms behind the up to 30-fold elevations in secretion of these hormones following surgery? Constantly with a translational scope, all elements involved in these responses will be addressed in this project, from detailed analysis of food items responsible for hormone secretion, to identification of the responsible regions of the gut, and to the molecular mechanisms leading to hypersecretion. Novel approaches for studies of human gut hormone secreting cells, including specific expression analysis, are combined with our advanced and unique isolated perfused gut preparations, the only tool that can provide physiologically relevant results with a translational potential regarding regulation of hormone secretion in the gut. This will lead to further groundbreaking experimental attempts to mimic and engage the identified mechanisms, creating similar hypersecretion and obtaining similar improvements as the operations in patients with obesity and diabetes. Based on our profound knowledge of gut hormone biology accumulated through decades of intensive and successful research and our successful elucidation of the antidiabetic actions of gastric bypass surgery, we are in a unique position to reach this ambitious goal.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["695069"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["USTAV MOLEKULARNI GENETIKY AKADEMIE VED CESKE REPUBLIKY VEREJNA VYZKUMNA INSTITUCE", "USTAV MOLEKULARNI GENETIKY AKADEMIE VED CESKE REPUBLIKY VEREJNA VYZKUMNA INSTITUCE", "SLOVENSKA ZDRAVOTNICKA UNIVERZITA V BRATISLAVE"], "EU_Contribution": ["EUR 1 950 000"], "Project_Title": ["Dicer-Dependent Defense in Mammals"], "Total_Cost": ["EUR 1 950 000"], "Country": ["Czech Republic", "Czech Republic", "Slovakia"], "Project_ACR": ["D-FENS"], "Technology_Description": "Viral infection or retrotransposon expansion in the genome often result in production of double-stranded RNA (dsRNA). dsRNA can be intercepted by RNase III Dicer acting in the RNA interference (RNAi) pathway, an ancient eukaryotic defense mechanism. Notably, endogenous mammalian RNAi appears dormant while its common and unique physiological roles remain poorly understood. A factor underlying mammalian RNAi dormancy is inefficient processing of dsRNA by the full-length Dicer. Yet, a simple truncation of Dicer leads to hyperactive RNAi, which is naturally present in mouse oocytes.", "To": ["2020-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Czech Republic"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2015-07-01"], "Project_ID": ["647403"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 246 668,40"], "Project_Title": ["Coupling ATomistics and mesoscAle Plasticity for toUghness of noveL hybrid maTerial"], "Total_Cost": ["EUR 246 668,40"], "Country": ["France"], "Project_ACR": ["CATAPULT"], "Technology_Description": "The project is one of an interactive synergism between theoretical modelling at UC Berkeley's MSE department and the CNRS-LEM and multiple length-scale structural/mechanical characterization and innovative processing at UCB. The researcher will lead the project under the supervision of Pr. Asta (UCB) and Dr. Finel (LEM). The work will be done in strong collaboration with Dr. Devincre (LEM) and experimentalist Pr. Ritchie (UCB). As structural materials reach their performance limits, one of the major scientific challenges for the 21st century is the development of new lightweight, high-performance structural materials to support advances in diverse strategic fields from building to transportation or energy. Tomsia and Ritchie have designed a freeze-casting technique to synthesize materials that closely mirror the hierarchical microstructure of nacre, producing the highest toughness ceramics on record. Now, our goal is to improve the material strength as well as toughness. Preliminary results have been recently obtained in the form of Al2O3/Al-Si composites exhibiting high toughness but a strength still 30% lower than pure metal. Our project aims to identify, characterize and model the material fracture, involving physical processes at many length scales and, finally, to design hybrid material with optimized mechanical properties. Our efforts to define the scientific mechanisms needed to develop such new damage-tolerant materials will follow an innovative multi-scale approach: combination of first-principles modelling of the interfaces and micro-mechanics models of bulk elastic and plastic relaxation, together with experimental data.", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2017-02-01"], "Project_ID": ["702731"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["EBERHARD KARLS UNIVERSITAET TUEBINGEN", "UNIVERSIDAD DE MURCIA", "KUNGLIGA TEKNISKA HOEGSKOLAN", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN", "CARL ZEISS VISION INTERNATIONAL GMBH", "VOPTICA S.L."], "EU_Contribution": ["EUR 3 544 115,04"], "Project_Title": ["Myopia: Fundamental understanding needed"], "Total_Cost": ["EUR 3 544 115,04"], "Country": ["Germany", "Spain", "Sweden", "Spain", "Ireland", "Germany", "Spain"], "Project_ACR": ["MyFUN"], "Technology_Description": "The proposed ETN \u201cMyopia: fundamental understanding needed\u201d (MyFUN) provides an international, interdisciplinary platform to train young scientists at the interface of physics and biology, to study unresolved questions about the visual control of eye growth. It has been extensively documented that the growth of the eye is controlled by closed-loop visual feedback, using retinal image defocus as an error signal. However, with tense education, predominant indoor activity and extensive near work, the eyes of young people grow too long and become near-sighted (myopic), reaching a prevalence of 95% in some Asian cities and 50% at German universities. While myopia is clearly a civilization disorder, it is strikingly unclear by which visual stimuli it is triggered, and how it can be stopped. Emerging optical interventions have still only moderate effects. There are fundamental questions, like \u201cWhy does myopia not limit itself?\u201d, \u201cWhy does undercorrection not reduce its progression?\u201d, \u201cWhy are the effects of new spectacle designs to inhibit myopia so small?\u201d, \u201cWhat determines when it starts and can we find biological markers to predict myopia in individual cases?\u201d. We propose a scheme of novel experiments, divided into 14 research projects that all have sufficient scientific depth and merit to merge into 14 successful PhD theses. The answers to the research questions will fundamentally improve our understanding of myopia, will be recognized worldwide and will represent a major contribution of the European Community to the global problem of the rising incidence of myopia. Our consortium consists of 7 Beneficiaries, combining the expertise of 5 academic partners with excellent research and teaching records and 2 fully integrated private sector partners. MyFUN will be supported by a management team experienced in multi-site training activities and counselled by a scientifically accomplished External Advisory Board.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-01-01"], "Project_ID": ["675137"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["STARLAB BARCELONA SL", "Forschungsgesellschaft f\u00fcr Arbeitsphysiologie und Arbeitsschutz e.V.", "UNIVERSITE DE LIEGE", "UNIVERSITA DEGLI STUDI DI MILANO", "EBERHARD KARLS UNIVERSITAET TUEBINGEN", "INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH"], "EU_Contribution": ["EUR 3 925 588,50"], "Project_Title": ["Studying, Measuring and Altering Consciousness through information theory in the electrical brain"], "Total_Cost": ["EUR 3 925 588,75"], "Country": ["Spain", "Germany", "Belgium", "Italy", "Germany", "France", "United Kingdom", "Germany"], "Project_ACR": ["LUMINOUS"], "Technology_Description": "What is consciousness? Can it be measured? While humankind has struggled with these questions for millennia, our project will focus on more modest but nonetheless ambitious and related goals. Inspired by recent developments in neuroscience and the potential role of fundamental concepts such as information integration and algorithmic complexity, we will study, model, quantify, and alter observable aspects of consciousness. Our vision is that consciousness will someday be electromagnetically measured and altered, and that the associated needed insights will prove crucial to the development cognitive sciences. ", "To": ["2019-08-31, ongoing project |"], "Meta": [""], "Topic_s": ["FETOPEN-1-2014 - FET-Open research projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Spain"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2016-03-01"], "Project_ID": ["686764"], "Call_for_Proposal": ["H2020-FETOPEN-2014-2015-RIA"]}, -{"Partners": ["EBERHARD KARLS UNIVERSITAET TUEBINGEN", "EBERHARD KARLS UNIVERSITAET TUEBINGEN"], "EU_Contribution": ["EUR 1 497 125"], "Project_Title": ["Biochemically modified messenger RNA encoding nucleases for in vivo gene correction of severe inherited lung diseases"], "Total_Cost": ["EUR 1 497 125"], "Country": ["Germany", "Germany"], "Project_ACR": ["BREATHE"], "Technology_Description": "Surfactant Protein B (SP-B) deficiency and Cystic Fibrosis (CF) are severe, fatal inherited diseases affecting the lungs of ten thousands of people, for which there is currently no available cure. Although gene therapy is a promising therapeutic approach, various technical problems, including numerous physical and immune-mediated barriers, have prevented successful application to date. My recent studies were the first to demonstrate the life-saving efficacy of repeated pulmonary delivery of chemically modified messenger RNA (mRNA) in a mouse model of congenital SP-B deficiency. By incorporating balanced amounts of modified nucleotides to mimic endogenous transcripts, I developed a safe and therapeutically efficient vehicle for lung transfection that eliminates the risk of genomic integration commonly associated with DNA-based vectors. I also assessed the delivery of mRNA-encoded site-specific nucleases to the lung to facilitate targeted gene correction of the underlying disease-causing mutations. In comprehensive studies, we show that a single application of nucleases encoded by nucleotide-modified RNA (nec-mRNA) can generate in vivo correction of terminally differentiated alveolar type II cells, which more than quadrupled the life span of SP-B deficient mice. Together with my working group, I aim to further develop this technology to enhance the efficiency and safety of nec-mRNA-mediated in vivo lung stem cell targeting, providing an ultimate cure by permanent correction. Specifically, we will test this approach in humanized mouse models of SP-B deficiency and CF. Developing and genetically engineering humanized models in vivo will be a critical step towards the safe translation of mRNA based nuclease technology to the clinic. With my competitive edge in lung-transfection technology and strong data, I feel that my group is uniquely suited to achieve these goals and to make a highly valuable contribution to the development of an efficient treatment.", "To": ["2020-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-04-01"], "Project_ID": ["637752"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["EBERHARD KARLS UNIVERSITAET TUEBINGEN", "EBERHARD KARLS UNIVERSITAET TUEBINGEN"], "EU_Contribution": ["EUR 1 998 898"], "Project_Title": ["Functional in vivo analysis of cholangiocarcinoma development, progression and metastasis."], "Total_Cost": ["EUR 1 998 898"], "Country": ["Germany", "Germany"], "Project_ACR": ["CholangioConcept"], "Technology_Description": "Genetic heterogeneity and complexity are hallmarks of metastatic solid tumors and therapy resistance inevitably develops upon treatment with cytotoxic drugs or molecular targeted therapies. Cholangiocarcinoma (CCC, or bile duct cancer) represents the second most frequent primary liver tumor and has emerged as a health problem with sharply increasing incidence rates, in particular of intrahepatic CCC (ICC). The reason for increased CCC incidence remains unclear, but influences of western lifestyle and a resulting altered hepatic metabolism have been discussed. Surgical resection represents the only curative option for the treatment of CCC, however, many tumors are irresectable at the time of diagnosis. CCC represents a highly aggressive and metastatic tumor type and currently no effective systemic therapy regimen exists. The overall molecular mechanisms driving CCC formation and progression remain poorly characterized and it thus becomes clear that a detailed molecular characterization of cholangiocarcinogenesis and the identification of robust therapeutic targets for CCC treatment are urgently needed. Taking advantage of our strong expertises in chimaeric (mosaic) liver cancer mouse models and stable in vivo shRNA technology, we here propose a comprehensive and innovative approach to i) dissect molecular mechanisms of cholangiocarcinogenesis, with a particular emphasis on Kras driven ICC development from adult hepatocytes and oncogenomic profiling of ICC metastasis, ii) to employ direct in vivo shRNA screening to functionally identify new therapeutic targets for CCC treatment and iii) to characterize the role of the gut microbiome for CCC progression and metastasis. We envision this ERC-funded project will yield important new insights into the molecular mechanisms of CCC development, progression and metastasis. As our work comprises direct and functional strategies to identify new vulnerabilities in CCC, the obtained data harbor a very high translational potential.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["648084"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["EBERHARD KARLS UNIVERSITAET TUEBINGEN", "EBERHARD KARLS UNIVERSITAET TUEBINGEN"], "EU_Contribution": ["EUR 1 808 200"], "Project_Title": ["Site-directed RNA Editing to Manipulate RNA and Protein Function"], "Total_Cost": ["EUR 1 808 200"], "Country": ["Germany", "Germany"], "Project_ACR": ["RNArepair"], "Technology_Description": "Enzymatically active RNA-guided proteins, like the RNA-induced silencing complex (RISC), are particularly versatile tools for the rationally programmed manipulation of genetic information. After successful re-addressing of various natural RNA-guided machineries it is now time to tackle the engineering of novel, user-defined tools. With this respect we have recently achieved the engineering of an RNA-guided adenosine-to-inosine RNA editing machinery. Since inosine is biochemically read as guanosine, A-to-I editing alters genomic information on the RNA-level and may potentially allow for the manipulation of RNA processing or protein function. We have already achieved to apply our RNA editing approach for the repair of several missense and nonsense point mutations on reporter and disease-related genes in vitro and demonstrated its applicability in mammalian cell culture.", "To": ["2020-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-08-01"], "Project_ID": ["647328"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["PANEPISTIMIO THESSALIAS"], "EU_Contribution": ["EUR 164 653,20"], "Project_Title": ["Music in Detention during the (Post) Civil-War Era in Greece (1947-1957)"], "Total_Cost": ["EUR 164 653,20"], "Country": ["Greece"], "Project_ACR": ["MUSDEWAR"], "Technology_Description": "MUSDEWAR will investigate the use of music in Greek prison camps in the (post) civil-war era (1947-1957). Despite a recent shift in musicology, which has begun to address music\u2019s potential to damage subjectivity, there are still major gaps in the history of music\u2019s use in mass detention camps. Contributing to the wider history of detention camps in the twentieth century, MUSDEWAR will fill this gap by critically examining: (1) the use of music as a means to \u2018re-educate\u2019, punish, humiliate and \u2018break\u2019 prisoners; (2) \u2018performance under orders\u2019: official camp orchestras and choirs; (3) music compositions, performances, and debates on Greek music by intellectuals-detainees. Analysing these aspects will combine historical and empirical research with a critical and theoretical framework. The project will document and reconstruct the use of music and musical life in the camps through archival and textual research, and interviews with former detainees, composers and intellectuals of the time. An interdisciplinary framework will be developed to analyse and interpret research findings, using tools from musicology, history, philosophy, trauma studies and critical theory. MUSDEWAR will deliver a monograph to a major international academic publisher. Moving beyond the humanistic notion of music as an inherently enlightening art, the monograph will synthesize research into an empirically rich and theoretically grounded account of the multifaceted use of music in the Greek camps. Intermediate aims include a project website and two articles to peer-reviewed journals. Actions for networking and knowledge transfer include research presentations, a workshop, a public outreach event (symposium, exhibition), projects in secondary schools, and a proposal for a European Research Council Starting Grant. Results will contribute directly to trans-national public debates about human rights and current forms of detention, particularly with regard to mass asylum seeking in the European Union.", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["Greece"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["706016"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["REGION HOVEDSTADEN"], "EU_Contribution": ["EUR 200 194,80"], "Project_Title": ["Omics Phenotyping of Endocrine Disease in the General Population"], "Total_Cost": ["EUR 200 194,80"], "Country": ["Denmark"], "Project_ACR": ["OPEDGP"], "Technology_Description": "Metabolomics is a relatively new technology that provides information about levels of human metabolites, the low molecule products at the end (downstream) of the metabolic pathways of human physiology. In theory, metabolite profiles may more closely reflect the clinical phenotype and thus potentially improve risk prediction. Another advantage is that that they can be performed on non-invasive biofluids like urine. Several metabolomics studies have suggested that the metabolite profile of an individual can be used as a predictor of type 2 diabetes. However, evidence from large-scale population-based studies with comprehensive phenotypes of diabetes and thyroid disease is limited. The aim of the project is to identify urine metabolite profiles associated with risk of diabetes and thyroid disease and to investigate pathogenetic pathways by identifying genetic determinants of these metabolites. The project takes advantage of the long tradition of population-based and registry-based epidemiological research in Denmark. The experienced researcher will complete a training program supervised by two recognised Danish research institutions with complementary expertise in the fields of epidemiology and genetics, respectively. Hereby the experienced researcher will achieve competences in the field of statistical modelling of epidemiological data with repeated measures and use of the unique Danish registries for research. Furthermore, during the secondment at the partner institution the experienced researcher will receive training in genetic epidemiology. In return, knowledge of metabolomics will be translated to the beneficiary and partner organizations. It is expected that the results will provide novel insights into the pathophysiology of diabetes and thyroid disease and identify novel biomarkers to improve risk prediction in individuals.", "To": ["2017-07-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-08-01"], "Project_ID": ["657595"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["MALMO HOGSKOLA"], "EU_Contribution": ["EUR 185 857,20"], "Project_Title": ["Molecular Imprinting mediated regulation of cell behavior and related biomedical applications"], "Total_Cost": ["EUR 185 857,20"], "Country": ["Sweden"], "Project_ACR": ["MIP4CELL"], "Technology_Description": "Tissue engineering or regenerative medicine, with its ultimate aim of developing true human replacement parts, has recently made enormous progress. The field refers to the use of human cells to replace or regenerate tissues or organs. Ideally, biomaterials for tissue engineering should efficiently mimic functionalities of the natural extracellular matrix (ECM). Hence surfaces of biomaterials should be engineered for dynamic control of cell behaviour. The objective of this proposal is to exploit molecular imprinting as a dynamic methodology for biofunctionalization and tissue engineering. Building on our previous proof of concept demonstration of systems for cell sheet harvesting, we expect to hereby obtain dynamic biofunctionalization of surfaces and overcome limitations of currently used methodologies (e.g. ligand leaching in non-covalent approach, loss of bioactivity in covalent approach, and lack of means for dynamic control of cells adhesion in both). The specific objectives of the proposal are as follows:", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["658953"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["EBERHARD KARLS UNIVERSITAET TUEBINGEN"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Morphogen-like properties of small RNA gradients: A new paradigm for the role of small RNAs in developmental biology"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["MorphGrad"], "Technology_Description": "This fellowship will investigate the mechanisms by which small RNAs function as novel intercellular messengers that provide important developmental signals. By manipulating various small RNA gradient and target parameters, the proposed research seeks to understand how small RNA gradients are interpreted into sharp gene expression domains. The findings from the proposed experiments will provide important insight into the patterning properties of small RNA gradients, and their role in conferring robustness to developmental programs in both plants and animals. The approach taken is a multidisciplinary one that integrates mathematical modelling with qualitative experimental data, generated from a novel reporter system and state-of-the-art confocal imaging and image analysis. The outcome will be a new paradigm for how miRNAs function in development, which will provide important insight into the patterning properties of small RNA gradients.", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-03-01"], "Project_ID": ["709293"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["EBERHARD KARLS UNIVERSITAET TUEBINGEN"], "EU_Contribution": ["EUR 239 860,80"], "Project_Title": ["The impact of climate change on the uptake of arsenic into rice"], "Total_Cost": ["EUR 239 860,80"], "Country": ["Germany"], "Project_ACR": ["RACe"], "Technology_Description": "Rice is the staple food worldwide. Unfortunately, global rice yield is already falling behind population growth. One of the reasons for this is the presence of toxic arsenic (As) in many South(-East) Asian paddy soils, which is known to decrease rice growth and productivity. The current change in Earth\u2019s climate is known to cause land loss due to desertification and inundation and lower (rice) crop yields, thus, threatening the global food security. According to the highest emission scenario for greenhouse gases presented in the 5th assessment report of the IPCC, global annual temperatures could rise by more than 5\u00b0C by the year 2100. How increased temperatures and CO2 concentrations affect As uptake into rice and ultimately the quality and production of rice is unknown and the main research question of this proposal. Rice will be grown in fully controlled growth chambers with elevated temperature and partial pressure of CO2, simulating the cli-mate of the year 2100. Besides determining changes in rice growth and grain yield, the amount of organic and inorganic As in the grain will be determined to assess rice quality. Furthermore, the biogeochemical pro-cesses occurring in the soil and atmosphere during climate change will be investigated and thus, will allow to understand the observed changes in rice yield and quality due to climate change. The amount and speciation of As will be quantified in the soil, plant, and atmosphere. Changes in microbial community abundance and richness will be assessed with modern pyrosequencing techniques. Functional microbial guilds of interest (iron and arsenic metabolizing bacteria) will be assessed by qPCR, pyrosequencing, and clone libraries. Overall, the knowledge obtained within the MSC-GF action on the impact of climate change on As uptake by rice will allow a better risk assessment for productivity of rice in the future and may give ideas for how to prevent a loss in rice yield and quality in a strongly climate impacted future.", "To": ["2019-03-29, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-03-30"], "Project_ID": ["661674"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["MUSEO STORICO DELLA FISICA E CENTRO STUDI E RICERCHE ENRICO FERMI", "ITA-SUOMEN YLIOPISTO", "Masarykova univerzita", "CHARLES RIVER DISCOVERY RESEARCH SERVICES FINLAND OY"], "EU_Contribution": ["EUR 540 000"], "Project_Title": ["Advanced MR methods for characterization of microstructural brain damage"], "Total_Cost": ["EUR 540 000"], "Country": ["Italy", "Finland", "Czech Republic", "Finland"], "Project_ACR": ["MICROBRADAM"], "Technology_Description": "NMR (Nuclear Magnetic Resonance)-based approaches have affirmed as extremely valuable for applications in neurosciences. Nonetheless, the exquisite flexibility of tissue contrast in magnetic resonance imaging (MRI) that can be obtained by proper manipulation of nuclear spins still offers room for technological improvements which can be quickly expanded to clinical routine. In particular, there is extreme need of imaging methods that allow a correct assessment of microstructural damage in many brain diseases, including \u2013 but not limited to \u2013 neurodegenerative diseases. Indeed, current MRI techniques suffer from poor specificity and ultimately lack the ability to identify the microscopic biophysical and biological mechanisms related to the specific features of the pathology.", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-11-01"], "Project_ID": ["691110"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["SCIENCE AND TECHNOLOGY FACILITIES COUNCIL", "UNIVERSITA DEGLI STUDI DI MILANO", "ATHINA-EREVNITIKO KENTRO KAINOTOMIAS STIS TECHNOLOGIES TIS PLIROFOFORIAS, TON EPIKOLNONION KAI TIS GNOSIS", "DEUTSCHES ZENTRUM FUER LUFT - UND RAUMFAHRT EV"], "EU_Contribution": ["EUR 1 999 983,75"], "Project_Title": ["Support to Reinforce the European Strategy Forum for Research Infrastructures"], "Total_Cost": ["EUR 1 999 983,75"], "Country": ["United Kingdom", "Italy", "Greece", "Germany"], "Project_ACR": ["STR- ESFRI"], "Technology_Description": "A 4 year \"Coordination and Support Action\" project led by the Science Technology Facilities Council (UK) in partnership with Universita degli Studi di Milano, (Italy), ATHENA Research and Innovation Centre, (Greece) and German Aerospace Center, DLR (Germany). ", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["INFRASUPP-5-2014 - Policy measures for research infrastructures"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations"], "From": ["2015-03-01"], "Project_ID": ["654213"], "Call_for_Proposal": ["H2020-INFRASUPP-2014-2"]}, -{"Partners": ["ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS", "NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA", "FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS", "PANEPISTIMIO PATRON", "PANEPISTIMIO THESSALIAS"], "EU_Contribution": ["EUR 205 413"], "Project_Title": ["2014-2015 Researchers' Night: The Greek events"], "Total_Cost": ["EUR 219 812,50"], "Country": ["Greece", "Greece", "Greece", "Greece", "Greece"], "Project_ACR": ["ReN2014-15"], "Technology_Description": "ReN2014-5 events will be organized during 2014 and 2015 and will take place in six major cities: i) Athens, Greece\u2019s capital, ii) Thessaloniki, iii) Patras, iv) Heraklion, v) Volos and for the first time in vi) Corfu, the capital of the Ionian Islands. These cities are spread almost nation-wide and cover more than two-thirds of Greece\u2019s total population ensuring a first-hand experience of ReN2014-5 activities from a large audience.", "To": ["2015-11-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-NIGHT-2014 - European Researchers' Night (NIGHT)"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Greece"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2014-06-01"], "Project_ID": ["633303"], "Call_for_Proposal": ["H2020-MSCA-NIGHT-2014"]}, -{"Partners": ["FONDAZIONE BRUNO KESSLER", "GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER", "TECHNISCHE UNIVERSITAET WIEN", "UNIWERSYTET WARSZAWSKI", "TECHNISCHE UNIVERSITEIT DELFT", "INSTITUT NATIONAL DE L'INFORMATION GEOGRAPHIQUE ET FORESTIERE", "ORDNANCE SURVEY LTD", "INSTITUT CARTOGRAFIC I GEOLOGIC DE CATALUNYA", "CENTRUL NATIONAL DE CARTOGRAFIE", "GEODETSKI ZAVOD CELJE IZVAJANJE STROKOVNO-OPERATIVNIH DEL STORITEV V ZADEVAH GEODETSKE SLUZBE TER DRUGIHSTROKOVNO TEHNICNIH DEL DOO", "VERMESSUNG AVT-ZT-GMBH", "VEXCEL IMAGING GMBH", "GEOIMAGING LIMITED"], "EU_Contribution": ["EUR 1 021 500"], "Project_Title": ["innoVation in geOspatiaL and 3D daTA"], "Total_Cost": ["EUR 1 021 500"], "Country": ["Italy", "Germany", "Austria", "Poland", "Netherlands", "France", "United Kingdom", "Spain", "Romania", "Slovenia", "Austria", "Austria", "Cyprus"], "Project_ACR": ["VOLTA"], "Technology_Description": "Geodata are datasets that have a spatial, temporal and thematic aspect to describe phenomena and processes in time, space and topic. Geodata, or geospatial data, are nowadays collected and produced with various sensors and techniques which provide for images, 3D point clouds, thematic maps, etc. Geodata are used in many Geosciences and for various applications such as urban planning, territorial management, damage assessment, environmental monitoring, 3D city modelling, renewable energy assessment, land registry, heritage documentation, etc. Despite a growing market, a large number of applications, a vast series of publications and various acquisition and processing techniques, there are still many unresolved research questions on the automation of processing procedures, and on how to make them more reliable, powerful and scale-invariant. Moreover, an efficient availability, access and use of geospatial data are often missing. This hinders the growth of new applications and societal welfares. Progress in provision of efficiently and effectively derived 3D geospatial information is thus the key to more comprehensive, faster and better exploitation of geodata, for the benefit of individuals and societies. Last but not least, new occupations are emerging in the geospatial industry which requires capacity building for developing new applications of geospatial technologies. The VOLTA project, through secondments, training activities and networking, will facilitate knowledge exchange and career progresses in the geospatial field. The project will develop innovative solutions to (i) automatically provide metric information from images, (ii) fuse heterogeneous data coming from various sensors, (iii) segment 2D and 3D geospatial data and (iv) process large geospatial datasets in the Cloud. The project will share and exploit the complementary expertise of the partners to produce and transfer new skills and innovative solutions for mapping agencies and geospatial companies.", "To": ["2021-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-06-01"], "Project_ID": ["734687"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["LAPIN YLIOPISTO", "UNIVERSITY OF LEEDS", "PACO DESIGN COLLABORATIVE", "POLYTECHNIC OF NAMIBIA PON"], "EU_Contribution": ["EUR 945 000"], "Project_Title": ["Participatory Tools for Human Development with the Youth"], "Total_Cost": ["EUR 945 000"], "Country": ["Finland", "United Kingdom", "Italy", "Namibia"], "Project_ACR": ["PARTY"], "Technology_Description": "Challenges faced by the marginalized youth in developing countries, such as unemployment, are not simple or easily solved. This is influenced by a number of factors including levels of education, gender, self-esteem, geographic location, physical ability and transport. The objective of the project is to contribute to solving the issues related to the youth unemployment in developing countries by creating participatory tools for human development that enable transformational change for the youth. Based on a service design approach, the project will provide tools for the marginalized youth suitable for daily use, enhancing regional democracy, increasing equal opportunities and contributing to human and service development with a particular target group: the San people in South Africa and Namibia. The San are faced with various social, cultural and political difficulties, and their communities are among the poorest in their countries, which are among the most unequal societies in the world. The tools aim to support the youth\u2019s motivation and abilities to participate in the development of their own community towards a wider integration into their national socio-economic systems. ", "To": ["2019-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-02-01"], "Project_ID": ["645743"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich"], "EU_Contribution": ["EUR 2 495 755"], "Project_Title": ["Tailored chemical complexity through evolution-inspired synthetic biology"], "Total_Cost": ["EUR 2 495 755"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["SynPlex"], "Technology_Description": "Creating true molecular complexity in a modular, combinatorial fashion is one of the great visions in applied enzymology and chemistry. Nature achieves this feat by using modular biosynthetic enzymes. These microbial proteins generate many of the most important natural products of therapeutic value, including antiinfective, anticancer, and immunosuppressive agents. To construct such compounds, each enzyme module incorporates and often modifies one building block in an assembly line-like process. Among the known modular enzymes, the recently discovered trans-acyltransferase polyketide synthases (trans-AT PKSs) exhibit an unparalleled biosynthetic diversity and tendency to form extensively mosaic-like hybrid enzymes during evolution. As a consequence, many bioactive polyketides generated by these enzymes exhibit combinatorial-like hybrid structures. This phenomenon provides unprecedented opportunities to understand the evolution of metabolic complexity and to apply these principles to metabolic engineering through parts-based synthetic biology. SynPlex will use a novel hypothesis-driven, multi-faceted strategy to interrogate and utilize the distinct combinatorial properties and metabolic richness of trans-AT PKSs. This multidisciplinary project aims to (i) unravel principles of how mosaic PKSs and their metabolites are formed in Nature, (ii) characterize non-canonical PKS components, (iii) create a toolbox of PKS parts for synthetic biology based on these evolutionary and biochemical principles, and (iv) harness the combinatorial potential of trans-AT systems to access complex natural as well as non-natural products. This innovative concept that merges evolutionary biology, enzymology, synthetic biology, and chemistry will result in a broad understanding of these most complex of all known proteins. It has the potential to provide generic, robust synthetic biology platforms to engineer complex polyketides with a wide range of features in a predictable way.", "To": ["2022-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["742739"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["Social Distress Response in the Context of Empathy in Rats"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["SOCIORATS"], "Technology_Description": "\"Why do humans behave pro-socially to such an extent that it supports the life of other individuals? Similarly, why do certain people harm others by hurting and sometimes killing? Finally, how can we promote pro-sociality and limit harmful actions? The philosopher and economist Adam Smith considered that what motivates us to help a person is that we can \"place ourselves in his situation, we conceive ourselves enduring all the same torments\", thus, holding empathy as the driving force of prosociality. ", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Research Organisations"], "From": ["2017-06-01"], "Project_ID": ["745885"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ACADEMISCH ZIEKENHUIS GRONINGEN"], "EU_Contribution": ["EUR 1 674 240"], "Project_Title": ["Personalised Medicine in Diabetic Chronic Disease Management"], "Total_Cost": ["EUR 3 348 480"], "Country": ["Netherlands"], "Project_ACR": ["PROMINENT"], "Technology_Description": "Diabetes is increasing rapidly from 415 million patients in 2015 to 642 million patients by 2040. As a result, it will become the leading disease worldwide, affecting 1 out of 10 persons globally and 3 out of 4 in low and middle income countries. The World Health Organisation marked World Health Day 2016 as calling for action on diabetes. Despite successful treatment of the inadequate glucose handling, diabetic patients show long-term effects of the disease such as a progressive loss of multiple organ function, in particular in the cardiovascular and renal systems. About half of the diabetic patients are at risk for renal complications associated with a markedly increased disease burden and death rate, the latter even surpassing the death rate in all treated cancer patients. The major reason for the lack of treatment efficacy is the large variation in individual response to the treatment. Consequently, we are left with a huge unmet need in the treatment of this chronic disease. ", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2016 - Co-funding of regional, national and international programmes"], "Funding_scheme": ["MSCA-COFUND-DP - Doctoral programmes"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["754425"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2016"]}, -{"Partners": ["ETHNIKO DIKTYO EREVNAS TECHNOLOGIAS AE", "THE CYPRUS INSTITUTE", "INSTITUTE OF INFORMATION AND COMMUNICATION TECHNOLOGIES", "INSTITUT ZA FIZIKU", "KORMANYZATI INFORMATIKAI FEJLESZTESI UGYNOKSEG", "NEMZETI INFORMACIOS INFRASTRUKTURA FEJLESZTESI IRODA", "UNIVERSITATEA DE VEST DIN TIMISOARA", "UNIVERSITETI POLITEKNIK I TIRANES", "UNIVERZITET U BANJOJ LUCI", "Ss. CYRIL AND METHODIUS UNIVERSITY IN SKOPJE", "JAVNA USTANOVA UNIVERZITET CRNE GORE PODGORICA", "RESEARCH AND EDUCATIONAL NETWORKING ASSOCIATION OF MOLDOVA", "INSTITUTE FOR INFORMATICS AND AUTOMATION PROBLEMS OF THE NATIONAL ACADEMY OF SCIENCES OF THE REPUBLIC OF ARMENIA", "GEORGIAN RESEARCH AND EDUCATIONAL NETWORKING ASSOCIATION", "BIBLIOTHECA ALEXANDRINA*LIBRARY OFALEXANDRIA BIBALEX", "MACHBA - INTERUNIVERSITY COMPUTATION CENTER", "SYNCHROTRON-LIGHT FOR EXPERIMENTAL SCIENCE AND APPLICATIONS IN THE MIDDLE EAST"], "EU_Contribution": ["EUR 3 300 000"], "Project_Title": ["VRE for regional Interdisciplinary communities in Southeast Europe and the Eastern Mediterranean"], "Total_Cost": ["EUR 3 300 000"], "Country": ["Greece", "Cyprus", "Bulgaria", "Serbia", "Hungary", "Hungary", "Romania", "Albania", "Bosnia and Herzegovina", "Former Yugoslav Republic of Macedonia", "Montenegro", "Moldova", "Armenia", "Georgia", "Egypt", "Israel", "Jordan"], "Project_ACR": ["VI-SEEM"], "Technology_Description": "In the last decade, a number of initiatives were crucial for enabling high-quality research - by providing e-Infrastructure resources, application support and training - in both South East Europe (SEE) and Eastern Mediterranean (EM). They helped reduce the digital divide and brain drain in Europe, by ensuring access to regional e-Infrastructures to new member states, states on path to ascension, and states in European Neighborhood Policy area \u2013 in total 14 countries in SEE and 6 in EM. This VI-SEEM proposal brings together these e-Infrastructures to build capacity and better utilize synergies, for an improved service provision within a unified Virtual Research Environment (VRE) for the inter-disciplinary scientific user communities in the combined SEE and EM regions (SEEM).", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["EINFRA-9-2015 - e-Infrastructures for virtual research environments (VRE)"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Greece"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other", "Research Organisations", "Other", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2015-10-01"], "Project_ID": ["675121"], "Call_for_Proposal": ["H2020-EINFRA-2015-1"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 2 499 500"], "Project_Title": ["Dynamic Interplay between Energy and Memory"], "Total_Cost": ["EUR 2 499 500"], "Country": ["France", "France"], "Project_ACR": ["EnergyMemo"], "Technology_Description": "Understanding the links between neuronal plasticity which underlies memory and energy metabolism is a major goal of brain studies. The brain is a main energy consumer and the central regulator of energy homeostasis, and it prioritizes its own supply over peripheral organs. Interestingly, our work demonstrates that the brain is also able to regulate its own activity under energy shortage to favor survival.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-10-01"], "Project_ID": ["741550"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["DANMARKS TEKNISKE UNIVERSITET", "DANMARKS TEKNISKE UNIVERSITET"], "EU_Contribution": ["EUR 2 500 000"], "Project_Title": ["Discovering new Catalysts in the Cluster-Nanoparticle Transition Regime"], "Total_Cost": ["EUR 2 500 000"], "Country": ["Denmark", "Denmark"], "Project_ACR": ["CLUNATRA"], "Technology_Description": "The purpose of this proposal is to establish new fundamental insight of the reactivity and thereby the catalytic activity of oxides, nitrides, phosphides and sulfides (O-, N-, P-, S- ides) in the Cluster-Nanoparticle transition regime. We will use this insight to develop new catalysts through an interactive loop involving DFT simulations, synthesis, characterization and activity testing. The overarching objective is to make new catalysts that are efficient for production of solar fuels and chemicals to facilitate the implementation of sustainable energy, e.g. electrochemical hydrogen production and reduction of CO2 and N2 through both electrochemical and thermally activated processes. ", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["741860"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["THE HEBREW UNIVERSITY OF JERUSALEM", "THE HEBREW UNIVERSITY OF JERUSALEM"], "EU_Contribution": ["EUR 2 499 750"], "Project_Title": ["Coupled Nanocrystal Molecules: Quantum coupling effects via chemical coupling of colloidal nanocrystals"], "Total_Cost": ["EUR 2 499 750"], "Country": ["Israel", "Israel"], "Project_ACR": ["CoupledNC"], "Technology_Description": "Coupling of atoms is the basis of chemistry, yielding the beauty and richness of molecules and materials. Herein I introduce nanocrystal chemistry: the use of semiconductor nanocrystals (NCs) as artificial atoms to form NC molecules that are chemically, structurally and physically coupled. The unique emergent quantum mechanical consequences of the NCs coupling will be studied and tailored to yield a chemical-quantum palette: coherent coupling of NC exciton states; dual color single photon emitters functional also as photo-switchable chromophores in super-resolution fluorescence microscopy; electrically switchable single NC photon emitters for utilization as taggants for neuronal activity and as chromophores in displays; new NC structures for lasing; and coupled quasi-1D NC chains manifesting mini-band formation, and tailored for a quantum-cascade effect for IR photon emission. A novel methodology of controlled oriented attachment of NC building blocks (in particular of core/shell NCs) will be presented to realize the coupled NCs molecules. For this a new type of Janus NC building block will be developed, and used as an element in a Lego-type construction of double quantum dots (dimers), heterodimers coupling two different types of NCs, and more complex NC coupled quantum structures. To realize this NC chemistry approach, surface control is essential, which will be achieved via investigation of the chemical and dynamical properties of the NCs surface ligands layer. As outcome I can expect to decipher NCs surface chemistry and dynamics, including its size dependence, and to introduce Janus NCs with chemically distinct and selectively modified surface faces. From this I will develop a new step-wise approach for synthesis of coupled NCs molecules and reveal the consequences of quantum coupling in them. This will inspire theoretical and further experimental work and will set the stage for the development of the diverse potential applications of coupled NC molecules.", "To": ["2022-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["741767"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["THE HEBREW UNIVERSITY OF JERUSALEM", "THE HEBREW UNIVERSITY OF JERUSALEM"], "EU_Contribution": ["EUR 2 498 750"], "Project_Title": ["The emergence of Modern Hebrew as a case-study of linguistic discontinuity"], "Total_Cost": ["EUR 2 498 750"], "Country": ["Israel", "Israel"], "Project_ACR": ["EMODHEBREW"], "Technology_Description": "The pioneering enterprise I propose is the study of a particular type of linguistic discontinuity \u2013 language revival \u2013 inspired by the revival of Hebrew at the end of the 19th century. The historical and sociocultural dimensions the revival have been studied before, but not its linguistic dimensions. My main aim is to construct a model of the linguistic factors which have shaped the revival of Hebrew. I expect this model to provide clues for the understanding of the process of language revival in general. For a language to be revived, a new grammar must be created by its native speakers. I hypothesize that the new grammar is formed by some of the general principles which also govern other better known cases of linguistic discontinuity (creoles, mixed languages, emergent sign languages etc.). The model I will develop will lay the foundation for a new subfield within the study of discontinuity \u2013 the study of language revival. I will start with careful work of documenting the development of the grammar of Modern Hebrew, in particular its syntax, something which has not been done systematically before. One product of the project will be a linguistic application for the documentation and annotation of the novel syntactic constructions of Modern Hebrew, their sources in previous stages of Hebrew and in the languages with which Modern Hebrew was in contact at the time of the revival, and the development of these constructions since the beginning of the revival until the present time. The linguistic application will be made available on the web for other linguists to use and to contribute to. The institution of an expanding data-base of the syntactic innovations of Modern Hebrew which comprises both documentation/ annotation and theoretical modeling which could be applied to other languages makes this an extremely ambitious proposal with potentially wide-reaching ramifications for the revival and revitalization of the languages of ethno-linguistic minorities world wide.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["741360"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 657 055,52"], "Project_Title": ["Corrosion Initiation Mechanisms at the Nanometric/Atomic Scale"], "Total_Cost": ["EUR 1 657 055,52"], "Country": ["France", "France"], "Project_ACR": ["CIMNAS"], "Technology_Description": "The failure of metallic materials caused by corrosion strongly impacts our society with cost, safety, health and performance issues. The mechanisms of corrosion propagation are fairly well understood, and various means of mitigation are known even if research is still necessary to improve this knowledge or to develop corrosion protection for the application of new materials. The vision of CIMNAS is that a major breakthrough for corrosion protection lies in a deep understanding and control of the initiation stage triggering corrosion. Corrosion initiation takes place at the atomic/molecular scale or at a scale of a few nanometres (the nanoscale) on metal and alloy surfaces, metallic, oxidised or coated, and interacting with the corroding environment. The mission of CIMNAS is to challenge the difficulty of understanding corrosion initiation at the nanometric/atomic scale on such complex interfaces, ultimately aiming at designing more robust metallic surfaces via the understanding of corrosion mechanisms. The project is constructed on new ideas to achieve three knowledge breakthroughs, each answering a key question for the understanding of corrosion initiation on metal and alloy surfaces. It is envisioned that the model approach used and the achieved breakthroughs will open up a new horizon for research on corrosion initiation mechanisms at the nanoscale, and new opportunities for a knowledge-based design of novel corrosion protection technologies. Technologies presently at low TRL (Technology Readiness Level) will benefit from these breakthroughs. Resources will include a team of highly experienced and recognised researchers headed by the PI, a unique apparatus recently installed at the PI\u2019s lab, integrating surface spectroscopy, microscopy, and electrochemistry for in situ measurements in a closed system, novel experimental approaches, and a strong complementarity of experiments and modelling.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["741123"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["VIB", "VIB"], "EU_Contribution": ["EUR 1 999 660"], "Project_Title": ["Decoding and controlling cell-state switching: A bottom-up approach based on enhancer logic"], "Total_Cost": ["EUR 1 999 660"], "Country": ["Belgium", "Belgium"], "Project_ACR": ["cis-CONTROL"], "Technology_Description": "Cell-state switching in cancer allows cells to transition from a proliferative to an invasive and drug-resistant phenotype. This plasticity plays an important role in cancer progression and tumour heterogeneity. We have made a striking observation that cancer cells of different origin can switch to a common survival state. During this epigenomic reprogramming, cancer cells re-activate genomic enhancers from specific regulatory programs, such as wound repair and epithelial-to-mesenchymal transition.", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Belgium"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-06-01"], "Project_ID": ["724226"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["VIB", "VIB"], "EU_Contribution": ["EUR 1 996 705"], "Project_Title": ["Determining the instructive tissue signals and the master transcription factors driving Kupffer cell differentiation"], "Total_Cost": ["EUR 1 996 705"], "Country": ["Belgium", "Belgium"], "Project_ACR": ["KupfferCellNiche"], "Technology_Description": "We have recently shown that contrary to common hypotheses, circulating monocytes can efficiently differentiate into Kupffer cells (KCs), the liver-resident macrophages. Using self-generated knock-in mice that allow specific KC depletion, we found that monocytes colonize the KC niche in a single wave upon KC depletion and rapidly differentiate into self-maintaining KCs that are transcriptionally and functionally identical to their embryonic counterparts. This implies that: (i) access to the KC niche is tightly regulated, ensuring that monocytes do not differentiate into KCs when the KC niche is full but differentiate very efficiently into KCs upon temporary niche availability, and (ii) imprinting by the KC niche is the dominant factor conferring KC identity. Understanding which cells represent the macrophage niche, which signals produced by these cells imprint the tissue-specific macrophage gene expression profile and through which transcription factors (TxFs) this is mediated is emerging as the next challenge in the field. We here propose an original strategy combining state-of-the-art in silico approaches and unique in vivo transgenic mouse models to tackle this challenge specifically for KCs, the most abundant macrophage in the body. We hypothesize that the liver sinusoidal endothelial cell (LSEC) to which the KC is attached represents the most likely candidate to sense KC loss, recruit new monocytes and drive their differentiation into KCs. Thus, this proposal aims to: (I) determine the TxFs through which the niche imprints KC identity, (II) map the LSEC-KC crosstalk during KC development, (III) generate LSEC-specific knock-in mice to study LSECs in vivo, (IV) demonstrate which LSEC factors influence KC development and function. Importantly, understanding how the KC-TxFs and the LSEC-KC crosstalk control KC development and function will be essential for the development of novel therapeutic interventions for hepatic disorders in which KCs play a central role.", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Belgium"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-07-01"], "Project_ID": ["725924"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITEIT ANTWERPEN", "UNIVERSITEIT ANTWERPEN"], "EU_Contribution": ["EUR 1 966 530"], "Project_Title": ["Seeing things you don't see: Unifying the philosophy, psychology and neuroscience of multimodal mental imagery"], "Total_Cost": ["EUR 1 966 530"], "Country": ["Belgium", "Belgium"], "Project_ACR": ["STYDS"], "Technology_Description": "When I am looking at my coffee machine that makes funny noises, this is an instance of multisensory perception \u2013 I perceive this event by means of both vision and audition. But very often we only receive sensory stimulation from a multisensory event by means of one sense modality. If I hear the noisy coffee machine in the next room (without seeing it), then how do I represent the visual aspects of this multisensory event? ", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["726251"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["EBERHARD KARLS UNIVERSITAET TUEBINGEN"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Understanding the impact of parental occupation on gender differences in field of study choice in Germany"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["GENSEG"], "Technology_Description": "While in many countries women have been increasing their participation in higher education, fields of study continue to be segregated by gender. Men dominate the technical fields which include mathematics, engineering and the physical sciences, whereas women tend to engage in areas that have a social and caring dimension. Despite numerous policies to enhance gender equalities in society, gender segregation in higher education, ironically, appears to be more pronounced in post-industrial countries, such as Germany, than in developing/transforming societies.", "To": ["2019-10-01, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-02"], "Project_ID": ["749068"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ISTITUTO NAZIONALE DI FISICA NUCLEARE", "ISTITUTO NAZIONALE DI FISICA NUCLEARE"], "EU_Contribution": ["EUR 1 432 301"], "Project_Title": ["Modeling the Gravitational Spectrum of Neutron Star Binaries"], "Total_Cost": ["EUR 1 432 301"], "Country": ["Italy", "Italy"], "Project_ACR": ["BinGraSp"], "Technology_Description": "The most energetic electromagnetic phenomena in the Universe are believed to be powered by the collision of two neutron stars, the smallest and densest stars on which surface gravity is about 2 billion times stronger than gravity on Earth. However, a definitive identification of neutron star mergers as central engines for short-gamma-ray bursts and kilonovae transients is possible only by direct gravitational-wave observations. The latter provide us with unique information on neutron stars' masses, radii, and spins, including the possibility to set the strongest observational constraints on the unknown equation-of-state of matter at supranuclear densities. ", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-10-01"], "Project_ID": ["714626"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["IQUADRAT INFORMATICA SL", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE TECNOLOGIC DE TELECOMUNICACIONS DE CATALUNYA", "KUNGLIGA TEKNISKA HOEGSKOLAN", "ARISTOTELIO PANEPISTIMIO THESSALONIKIS", "TECHNISCHE UNIVERSITEIT EINDHOVEN", "EDUCATIONAL OTE AE", "III-V LAB", "SIAE MICROELETTRONICA SPA"], "EU_Contribution": ["EUR 3 797 921,88"], "Project_Title": ["5G System Technological Enhancements Provided by Fiber Wireless Deployments"], "Total_Cost": ["EUR 3 797 921,88"], "Country": ["Spain", "France", "Spain", "Sweden", "Greece", "Netherlands", "Greece", "France", "Italy"], "Project_ACR": ["5G STEP FWD"], "Technology_Description": "5G cellular networks are coming and they need to cope with major challenges in meeting the demands of large populations. The rapid increase of mobile devices, wireless connections and the emerging internet services related to applications with very diverse communication requirements (e.g., Smart grid, m-health, Smart cities), raised the need of higher capacity and more energy efficient networks with improved coverage capabilities. According to the 5G Public-Private Partnership (5GPPP) recently formed by the European Commission (EC), 5G networks should be capable of providing 1000 times higher capacity with 0% downtime, enabling the roll-out of very dense wireless networks that are able to connect over 7 trillion devices amongst 7 billion people. 5G STEP FWD aims at proposing, studying, optimizing, quantitatively assessing and comparing advantages and disadvantages of hybrid fiber \u2013 wireless architectures, topologies and technologies, which will significantly shape 5G standards and will enable the requested 1000 times increase of spectral efficiency and 90% reduction of energy consumption.", "To": ["2021-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Spain"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-06-01"], "Project_ID": ["722429"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["EBERHARD KARLS UNIVERSITAET TUEBINGEN", "EBERHARD KARLS UNIVERSITAET TUEBINGEN"], "EU_Contribution": ["EUR 149 238"], "Project_Title": ["PReparing Introduction to MArket of SKOTI (PRIMASKOTI) - a breakthrough solution for real-time studies of cytoskeletal motors at single-molecule resolution"], "Total_Cost": ["EUR 149 238"], "Country": ["Germany", "Germany"], "Project_ACR": ["PRIMASKOTI"], "Technology_Description": "The PRIMASKOTI project will prepare the commercialization of SKOTI\u2014the Swiss Knife for Optical Tweezers and Imaging. The scientific instrument SKOTI is designed to measure interactions between single biomolecules with a focus on cytoskeletal molecular machines. SKOTI combines several state-of-the-art microscopy techniques with contact-less mechanical manipulation, so-called optical tweezers. Because of its ultra high stability, SKOTI has its particular strengths in experiments requiring a solid support such as a glass surface. This requirement is often the case for cytoskeletal motor protein studies. Since these molecular machines are key to many essential cellular processes such as transport or cell division, being able to study their interactions is an important step towards understanding diseases such as cancer or neurodegeneration. However, due to the highly specialized knowledge necessary to build and operate such instruments, hardly commercially available, single-molecule experiments are difficult. By commercializing SKOTI, we aim to provide a simple-to-access tool which will broaden the scope of applications and users. SKOTI will provide a modular microscope and optical manipulation platform with unprecedented force- and displacement-resolution, ease of operation through motorization and automatization, flexibility, and overall stability of the system. The key idea is to commercialize a complete solution, where the instrument is supplemented with an isolation from the environment, operation and analysis software, specialized probes, service contracts, and kits for experiments that help to minimize preparation times. This approach will simplify single-molecule experiments, increase throughput, and lower barriers to engage in such studies. In the long term, our novel, cutting-edge research tool for life sciences will provide insight to essential cellular processes and pave the way for new medical approaches.", "To": ["2019-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["755161"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["EBERHARD KARLS UNIVERSITAET TUEBINGEN", "EBERHARD KARLS UNIVERSITAET TUEBINGEN"], "EU_Contribution": ["EUR 1 999 250"], "Project_Title": ["Human Evolution at the Crossroads"], "Total_Cost": ["EUR 1 999 250"], "Country": ["Germany", "Germany"], "Project_ACR": ["CROSSROADS"], "Technology_Description": "The most important open questions in European paleoanthropology concern the timing, number and origin of early human dispersals into the continent, the identity and number of taxa present, and their possible interactions. These issues remain unresolved partly due to the lack of research in South-East Europe, a region at the crossroads between continents and a refugium for fauna, flora and possibly human populations during glacial times. The PI\u2019s previous work there (ERC StG PaGE) aimed to add new evidence to further our understanding of human evolution on the continent. PaGE led to the discovery of several new Paleolithic sites, including the oldest radiometrically dated archaeological site from South-East Europe, placing the region squarely in the Paleolithic map of Europe. ", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["724703"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["TECHNISCHE UNIVERSITEIT DELFT"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["Bichromatic Structures for Robust propagation of Light"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["BISTRO-LIGHT"], "Technology_Description": "The investigation of topological effects in photonic systems is a thriving field of research in the nanophotonics community. Suitably designed nanostructures allow the formation of novel states for light which are more robust against disorder and less sensitive to back-scattering, spurring academic fascination and helping to improve photonic circuitry technology. Recent advances have greatly expanded the variety of systems displaying topological effects: for instance it has recently been shown that the Aubry-Andr\u00e9 model, a one-dimensional tight-binding model of particles with a periodically-modulated on-site energy, inherits the nontrivial topological properties of a higher-dimensional topological insulator.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["748950"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["POLITECNICO DI MILANO", "POLITECNICO DI MILANO"], "EU_Contribution": ["EUR 149 375"], "Project_Title": ["Innovative Neutron source for non destructive TEsting and tReatments"], "Total_Cost": ["EUR 149 375"], "Country": ["Italy", "Italy"], "Project_ACR": ["INTER"], "Technology_Description": "The INTER project aims at the design and production of a proof of concept demonstrator component essential for the development of a novel, tunable and portable neutron source. ", "To": ["2018-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["754916"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["THE UNIVERSITY OF EDINBURGH", "THE UNIVERSITY OF EDINBURGH"], "EU_Contribution": ["EUR 1 499 520"], "Project_Title": ["Establishing genetic code expansion as a tool to study neuronal circuit function in an animal"], "Total_Cost": ["EUR 1 499 520"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["UAAWORM"], "Technology_Description": "We pioneered technologies that allow the site-specific introduction of chemically synthesized unnatural amino acids (UAA) into a chosen protein within the context of a multicellular organism - the nematode worm C. elegans. The foundational technology for this advance is genetic code expansion.", "To": ["2021-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-04-01"], "Project_ID": ["679990"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["USTAV MOLEKULARNI GENETIKY AKADEMIE VED CESKE REPUBLIKY VEREJNA VYZKUMNA INSTITUCE"], "EU_Contribution": ["EUR 154 720,80"], "Project_Title": ["Identification of novel substrates for ubiquitin ligases involved in cell cycle and cell migration"], "Total_Cost": ["EUR 154 720,80"], "Country": ["Czech Republic"], "Project_ACR": ["LIGER"], "Technology_Description": "Cancer cells heavily rely on the proteasome-ubiquitin system mediated tuning of proteins stability and proteome composition. Proteasome and ubiquitin ligases targeting drugs are already in use against certain haematological cancers, and similar inhibitors are currently explored as a possibility for autoimmune diseases and parasite infestation treatment. E3 ubiquitin ligases are the ultimate target for these therapies as they determine specificity in substrate recognition. It is thus of utmost interest for both basic and translational research to find new ubiquitin ligases essential for cell proliferation, cell migration or cancer progression and couple them with their substrates. In the proposed LIGER project, we aspire to fuse cutting-edge methods to identify new ubiquitin ligase \u2013 substrate pairs. In particular, we will focus on E3 ubiquitin ligases involved in cancer progression and more specifically, in its two crucial aspects - cell growth and cell migration. To pre-select the ubiquitin ligases for further analysis, we will perform an unbiased screen for ubiquitin ligases that are involved in cell growth and cell migration. To achieve this goal, CRISPR library screening methodology will be employed. Consequentially, we will purify proteins associated with the selected ubiquitin ligases and identify their potential substrates. Standard biochemical and molecular biology methods will allow us to study in detail the protein interface between the ubiquitin ligases and their novel substrates and describe the biological function of their degradation. LIGER project will increase our understanding of ubiquitin pathway in physiological and pathological conditions and identify new potential targets for cancer therapy.", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Czech Republic"], "Activity": ["Research Organisations"], "From": ["2017-03-01"], "Project_ID": ["752074"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Polysaccharide-based membrane for sublingual vaccination"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["PolyVac"], "Technology_Description": "Vaccination has been acknowledged as one of the most effective methods against life-threatening diseases. Vaccines administered by the mucosal route (oral, vaginal\u2026) present the advantage to be needle-free and reduce the risk of pathogen transmission. Among the existing mucosal vaccines, the sublingual ones are an interesting way of immunization since the sublingual mucosa is particularly thin and would allow easy penetration of antigens. Also, this administration allows to bypass the gastrointestinal tract, has better safety record than intranasal vaccines and have better compliance for vaccinating infants and children. Additionally, they have a fast removal by body fluids and enzymes. PolyVac introduces a pioneering system for controlled targeted delivery of bioactive molecules and, for the proof of concept envisages the development of a sublingual vaccine for HIV. This concept comprises the development of a free-standing (FS) multilayer membrane that will present the double specificity to be immunoactive and specifically target the immune cells. To achieve this end, the FS will be loaded with a model antigen for immunotherapy and a chemotactic cytokine to specifically target the antigen presenting cells. Once loaded with the proteins, the FS membrane will become a bioactive patch. This patch will permit to deliver subunit vaccine components both spatially and temporally as dendritic cells will be attracted at the sublingual mucosa/patch interface ensuring efficient immune responses. Preclinical studies will follow in mice, by monitoring their immune response, for clinical translation and commercialisation of the proposed technology. It is expected to have, as final product, an innovative sublingual patch for human immunotherapy that among the advantages presented above will also overcome one of the main drawbacks of injected vaccines that is the storage at around 4\u00b0C. Overcoming this issue they could be widely used for immunotherapy in the developing countries.", "To": ["2019-07-06, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2017-07-07"], "Project_ID": ["751061"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["MALMO HOGSKOLA", "PHASE HOLOGRAPHIC IMAGING PHI AB", "TURUN YLIOPISTO", "BUNDESANSTALT FUER MATERIALFORSCHUNG UND -PRUEFUNG", "KOBENHAVNS UNIVERSITET", "UMEA UNIVERSITET"], "EU_Contribution": ["EUR 2 138 720,04"], "Project_Title": ["Imaging and detection of tumor-associated glycan structures on tumor cells"], "Total_Cost": ["EUR 2 138 720,04"], "Country": ["Sweden", "Sweden", "Finland", "Germany", "Denmark", "Sweden"], "Project_ACR": ["GlycoImaging"], "Technology_Description": "The overall objective of Glyco Imaging is to develop novel assays for detection of glycans as biomarkers associated with aggressive and metastatic cancer forms. The assays will be developed for biomarker detection in blood, urine, cells and tissue. Molecularly Imprinted Polymers (MIPs), or plastic antibodies, have been developed for targeting the human glycan sialic acid (SA), or Neu5Ac. The efficiency of the Neu5Ac specific SAMIPs targeted to the biomarker SA in different solvents (methanol, water, phosphate buffer) will be exploited. The non-human Neu5Gc, which is incorporated into human glycoconjugates through dietary sources such as red meat, and shown to be involved in malignant cell transformation in humans, will also be investigated by using highly specific Neu5Gc-SAMIPs. The imaging and detection techniques used will be based on fluorescence, 3D-viewing of cancer cells by digital holographic microscopy and magnetic separation columns.", "To": ["2021-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["721297"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN", "TECHNISCHE UNIVERSITAET WIEN", "UNIVERSITY OF GLASGOW", "DANMARKS TEKNISKE UNIVERSITET", "MEDIZINISCHE UNIVERSITAET WIEN", "REGION HOVEDSTADEN", "THE ANNA FREUD CENTRE", "TELEFONICA INVESTIGACION Y DESARROLLO SA", "REACHOUT IRELAND LTD"], "EU_Contribution": ["EUR 4 041 770,76"], "Project_Title": ["Technology Enabled Adolescent Mental Health"], "Total_Cost": ["EUR 4 041 770,76"], "Country": ["Ireland", "Austria", "United Kingdom", "Denmark", "Austria", "Denmark", "United Kingdom", "Spain", "Ireland"], "Project_ACR": ["TEAM"], "Technology_Description": "There is no health without mental health. 27% of our population are young, and mental health disorders are our leading cause of disability. 50% of mental disorders emerge by 14 yrs, 75% by 24 yrs and, untreated, triple odds of having a mental health disorder in later life. TEAM\u2019s will build a network of expertise and train a new generation of researchers to deliver more effective, affordable and feasible mental health services for young people. Our interdisciplinary, international, intersectoral network, balanced in skills, experience and perspectives, will train the next generation of researchers to lead Youth Mental Health (YMH) services into the future. Research objectives focus on key challenges in YMH: delivering new technologies to support rapid, large-scale, and early assessment, prevention and treatment.TEAM will also deliver policy directions and guidelines for technology-enabled YMH. 2 themes are covered: how can technology a) increase access, and b) help people to engage more successfully? TEAM will deliver new technology-enabled services that are both accessible and engaging for young people. Our ambitious objectives require individuals with a unique combination of interdisciplinary and intersectoral skills. TEAM ESRs will receive integrated training across three key areas necessary to fully realise the potential of technology-enabled mental health: Mental Healthcare Delivery - the theories and practice of YMH; Computer science - core principles in software engineering and technology infrastructures; Interaction Design - theories and methods including co-designing with young people and active engagement with clinicians, social workers, caregivers (e.g. parents) and teachers. Intersectoral secondments promote interdisciplinary and intersectoral learning and communication, and public engagement and outreach focus on young people, those who play major roles in their lives (e.g. parents and teachers), health care professionals.", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other"], "From": ["2016-11-01"], "Project_ID": ["722561"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["WEIZMANN INSTITUTE OF SCIENCE", "WEIZMANN INSTITUTE OF SCIENCE"], "EU_Contribution": ["EUR 2 287 500"], "Project_Title": ["Immune checkpoint blockade for fighting Alzheimer\u2019s disease"], "Total_Cost": ["EUR 2 287 500"], "Country": ["Israel", "Israel"], "Project_ACR": ["ImmuneCheckpointsAD"], "Technology_Description": "Understanding, and ultimately treating Alzheimer\u2019s disease (AD) is a major need in Western countries. Currently, there is no available treatment to modify the disease. Several pioneering discoveries made by my team, attributing a key role to systemic immunity in brain maintenance and repair, and identifying unique interface between the brain\u2019s borders through which the immune system assists the brain, led us to our recent discovery that transient reduction of systemic immune suppression could modify disease pathology, and reverse cognitive loss in mouse models of AD (Nature Communications, 2015; Nature Medicine, 2016; Science, 2014). This discovery emphasizes that AD is not restricted to the brain, but is associated with systemic immune dysfunction. Thus, the goal of addressing numerous risk factors that go awry in the AD brain, many of which are -as yet- unknown, could be accomplished by immunotherapy, using immune checkpoint blockade directed at the Programmed-death (PD)-1 pathway, to empower the immune system. In this proposal, we will adopt our new experimental paradigm to discover mechanisms through which the immune system supports the brain, and to identify key/novel molecular and cellular processes at various stages of the disease that are responsible for cognitive decline long before neurons are lost, and whose reversal or modification is needed to mitigate AD pathology, and prevent cognitive loss. Achieving our goals requires the multidisciplinary approaches and expertise at our disposal, including state-of-the art immunological, cellular, molecular, and genomic tools. The results will pave the way for developing a novel next-generation immunotherapy, by targeting additional selective immune checkpoint pathways, or identifying a specific immune-based therapeutic target, for prevention and treatment of AD. We expect that our results will help attain the ultimate goal of converting an escalating untreatable disease into a chronic treatable one.", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["741744"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["WEIZMANN INSTITUTE OF SCIENCE"], "EU_Contribution": ["EUR 170 509,20"], "Project_Title": ["Single cell analysis of the lung tumour-immune ecosystem: Developing new tools for effective immunotherapy"], "Total_Cost": ["EUR 170 509,20"], "Country": ["Israel"], "Project_ACR": ["SCALTIE"], "Technology_Description": "Tumours evolve to evade immune surveillance through a series of immune suppression mechanisms. In line with this, cancer immunotherapies, in which the immune system is turned on against tumours, are currently revolutionizing cancer treatment. Unfortunately, still many cancer patients do not respond to immunotherapies. Therefore, there is an urgent need to develop new tools for effective immunotherapy in order to increase treatment response rate. ", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["746382"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAT JAUME I DE CASTELLON"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Non-Invasive Fluorescence-based Tear Glucose Sensor Integrated to a Smartphone"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["GlucoTear"], "Technology_Description": "The prevalence of diabetes is continuously rising even in low-income economies. Therefore, blood glucose monitoring tools are in high social demand globally. Uninterrupted monitoring of blood glucose is a must in order to keep the fatal levels of glycated hemoglobin under control and to improve the quality of life for diabetic patients. However, glucose monitoring is compromised by the painful finger pricking about 4-5 times a day to obtain blood samples which leads to patient non-compliance and hence endangering their lifes.", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["751249"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["INTENDU LTD"], "EU_Contribution": ["EUR 182 509,20"], "Project_Title": ["Transforming Brain Rehabilitation"], "Total_Cost": ["EUR 182 509,20"], "Country": ["Israel"], "Project_ACR": ["FBT"], "Technology_Description": "Multiple diseases, injuries, and aging, may lead to executive dysfunctions, reducing quality of life. Intendu transforms brain rehabilitation, by introducing a novel platform of video games designed to train executive functions (EF). The games involve natural body gestures, and are adaptive in real-time to performance. Preliminary results show that training with Intendu\u2019s games is safe, leading to improved cognitive function. Robust evidence for the efficacy of Intendu\u2019s training program and brain plasticity mechanisms driving functional benefits is required. During this fellowship, and under Dr. Son Preminger\u2019s supervision, founder and CEO of Intendu; and of Drs. Debbie Rand and Doron Freidman, established researchers in virtual reality (VR), I will (1) receive a unique opportunity to combine my scientific passions \u2013 cognitive training and motor learning, video gaming and rehabilitation, basic and applied neuroscience \u2013 into one multidisciplinary, strongly founded field; (2) deepen my knowledge with executive functions; (3) broaden my experience with multiple clinical populations; (4) acquire regulatory and intellectual property legislation knowledge and experience; (5) grow my leadership skills; (6) gain working experience in a young startup. Building on these critical skills, and on my previous experience as a postdoctoral researcher at the University of California, Berkeley (UCB) and senior scientist at Posit Science Corporation (PSC), I hope to: (1) lead Intendu\u2019s research with local and international collaborators; manage a network of external research partners; build and manage Intendu\u2019s research team; (2) define scientific foundation for games with Intendu\u2019s product team; (3) assure research funding; (4) work closely with regulatory consultants to manage regulatory affairs, to clear the program as the first motion-controlled software-based medical treatment for cognitive impairments. Together, this fellowship will open my best career possibilities.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-SE - Society and Enterprise panel"], "Coordinated_in": ["Israel"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-06-01"], "Project_ID": ["753071"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["EBERHARD KARLS UNIVERSITAET TUEBINGEN", "EBERHARD KARLS UNIVERSITAET TUEBINGEN"], "EU_Contribution": ["EUR 1 497 643"], "Project_Title": ["A Silk Road in the Palaeolithic: Reconstructing Late Pleistocene Hominin Dispersals and Adaptations in Central Asia"], "Total_Cost": ["EUR 1 497 643"], "Country": ["Germany", "Germany"], "Project_ACR": ["PALAEOSILKROAD"], "Technology_Description": "In antiquity and the early Middle Ages, a network of trade routes known as the Silk Road connected east Asia and the \u041ciddle East. The Silk Road was not just an economic link, but also the avenue for cultural and even genetic exchanges between these regions. Recent genetic discoveries have hinted that such connections might have begun much earlier, during the Pleistocene. The Pleistocene period is of fundamental importance for human history. It is then that our ancestors evolved and colonised the entire Old World, surviving a suite of major extinction events \u2013 and they did so against a dramatic backdrop of ice ages and warmer interglacial phases which substantially altered their habitats. Conquering the extreme environments of arid central Asia to eventually settle the entire Asian mainland and beyond is one of the most impressive feats in this story. Unfortunately, there are too few known Pleistocene archaeological sites in central Asia to allow us to piece together when and how this happened. PALAEOSILKROAD will resolve this deficit by surveying central Asian mountain foothills as both corridors for human and animal movements and archives of past climate change. The project will discover new sites in the Tian Shan, Dzungar, and southern Altai foothills (Kazakhstan) and use them to examine if and how 1) humans were able to survive in the foothills throughout the last glacial cycle (110-11 500 years ago), and 2) periodic advances of mountain glaciers motivated dispersals, population segmentation, and behavioural adaptations. To address these questions, PALAEOSILKROAD will take an ambitious approach rooted in archaeology and contextualised by palaeoenvironmental reconstruction. The results of this project will change the way we understand human dispersals on a global scale and the resilience of early humans in the face of environmental challenges, providing a major missing link to explain how Homo sapiens became the only surviving species of our genus.", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["714842"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS", "NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA", "FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS", "PANEPISTIMIO PATRON", "PANEPISTIMIO THESSALIAS"], "EU_Contribution": ["EUR 258 750"], "Project_Title": ["Invitation to Researchers\u2019 Night 2016-2017 HEllas"], "Total_Cost": ["EUR 273 150"], "Country": ["Greece", "Greece", "Greece", "Greece", "Greece"], "Project_ACR": ["IRENE"], "Technology_Description": "IRENE project concerns the organization of the most successful Researchers\u2019 Night (RN) events in Greece as yet. 5 prestigious research organisations join forces and organize RN events in the most important Greek cities covering the country from north to south.", "To": ["2017-11-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-NIGHT-2016 - European Researchers' Night"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Greece"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["722935"], "Call_for_Proposal": ["H2020-MSCA-NIGHT-2016"]}, -{"Partners": ["NATIONAL OBSERVATORY OF ATHENS"], "EU_Contribution": ["EUR 164 653,20"], "Project_Title": ["Improving global dust prediction and monitoring through data assimilation of satellite-based dust aerosol optical depth"], "Total_Cost": ["EUR 164 653,20"], "Country": ["Greece"], "Project_ACR": ["DUST-GLASS"], "Technology_Description": "DUST-GLASS aims at improving global dust prediction and monitoring by optimizing an advanced data assimilation system (LETKF scheme) coupled with a sophisticated atmospheric-dust model (NMMB/BSC-Dust). For the accomplishment of these core scientific goals, a fine resolution (0.1o x 0.1o) global dust optical depth (DOD) database, suitable for data assimilation, will be developed via a synergy of state-of-the-art Level 2 satellite retrievals acquired by MODIS, MISR and OMI sensors (2007-2016). The impacts of assimilating this novel dataset (DOD) on model\u2019s predictive skills, both at global and regional scale, will be assessed objectively. Global forecasts (5 days) will be carried out for different periods aiming at studying dust aerosols\u2019 mobilization and transport from the major dust sources of the planet, while a global reanalysis (0.5o x 0.7o) dataset will be generated for long-term dust monitoring. In addition, regional short-term (84 hours) forecasts will be conducted for 20 Mediterranean dust outbreaks identified by a satellite algorithm in the framework of the MDRAF project (fellow\u2019s previous MC-IEF). In the evaluation analysis, the model\u2019s dust outputs will be compared versus measurements derived by ground networks (AERONET, MAN, ACTRIS) as well as against columnar/vertical satellite retrievals (MODIS, MISR, CALIOP). Moreover, temperature and radiation will be also considered since \u201ccorrections\u201d on dust fields, thanks to data assimilation, are expected to be evident on both parameters due to dust-radiation interactions. The aforementioned variables will be compared against observations obtained by ground networks (ISB, RAOB, BSRN) and reanalysis/analysis products (ERA-Interim, FNL). Considering the multifaceted role of dust, the scientific outcomes of DUST-GLASS are expected to contribute effectively to interdisciplinary studies regarding dust aerosols as well as their associated impacts on health, anthropogenic activities, environment, weather and climate.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Greece"], "Activity": ["Research Organisations"], "From": ["2017-05-01"], "Project_ID": ["749461"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["PANEPISTIMIO THESSALIAS"], "EU_Contribution": ["EUR 152 653,20"], "Project_Title": ["Exploring MIcrobial networking in pesticides biodeGRAdaTion: novel inocula and biocatalysts for biodepuration of agro-industrial Effluents"], "Total_Cost": ["EUR 152 653,20"], "Country": ["Greece"], "Project_ACR": ["EMIGRATE"], "Technology_Description": "Pesticides constitute priority pollutants for natural resources. Microbes, mostly in the form of microbial consortia are pivotal in the in situ pesticide biodegradation. EMIGRATE aims to investigate the complex interactions driving the coherence and biodegradation capacity of natural bacterial consortia, and through this, enable the production of biotechnological and bioengineering tools for novel environmental clean-up strategies. A microbial consortium degrading the fungicide thiabendazole used in fruit-packaging plants will be used as a model. This choice is based on the high biotechnological potential of this consortium considering the environmental risk associated with the use pattern, recalcitrance and toxicity of this fungicide and the complete lack of information regarding its microbial metabolism. Through its innovative research EMIGRATE will facilitate the re-integration of the fellow to the local and EU research community. Project's objectives will be achieved through 7 work-packages: WP1 will deal with project management, IPR and results exploitation, WP2 will focus on fellow's training and WP3 on the dissemination and public engagement of project's findings. WP4 will focus on the in-depth phylogenetic characterization of the bacterial consortium and the identification of the roles of consortium members on pesticide metabolism (Stable Isotope Probing - amplicon sequencing). WP5 will assign wider functional roles to consortium members, identify key catabolic genes and elucidate the metabolic pathway of the fungicide via a meta-genomics, -transcriptomics, -metabolomics approach. Finally, WP6 and WP7 will exploit the bacterial consortium for isolation of novel enzymes-biocatalysts and the development of an innovative biological process for the depuration of the relevant agro-industrial effluents. Secondments to academic and industrial partners will be carried out for skill development of the fellow on isotopic techniques, metabolomics and bioengineering.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Greece"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["749463"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["NATIONAL OBSERVATORY OF ATHENS", "NATIONAL OBSERVATORY OF ATHENS"], "EU_Contribution": ["EUR 1 968 000"], "Project_Title": ["Does dust triboelectrification affect our climate?"], "Total_Cost": ["EUR 1 968 000"], "Country": ["Greece", "Greece"], "Project_ACR": ["D-TECT"], "Technology_Description": "The recent IPCC report identifies mineral dust and the associated uncertainties in climate projections as key topics for future research. Dust size distribution in climate models controls the dust-radiation-cloud interactions and is a major contributor to these uncertainties. Observations show that the coarse mode of dust can be sustained during long-range transport, while current understanding fails in explaining why the lifetime of large airborne dust particles is longer than expected from gravitational settling theories. This discrepancy between observations and theory suggests that other processes counterbalance the effect of gravity along transport. D-TECT envisages filling this knowledge gap by studying the contribution of the triboelectrification (contact electrification) on particle removal processes. Our hypothesis is that triboelectric charging generates adequate electric fields to hold large dust particles up in the atmosphere. D-TECT aims to (i) parameterize the physical mechanisms responsible for dust triboelectrification; (ii) assess the impact of electrification on dust settling; (iii) quantify the climatic impacts of the process, particularly the effect on the dust size evolution during transport, on dry deposition and on CCN/IN reservoirs, and the effect of the electric field on particle orientation and on radiative transfer. The approach involves the development of a novel specialized high-power lidar system to detect and characterize aerosol particle orientation and a large-scale field experiment in the Mediterranean Basin using unprecedented ground-based remote sensing and airborne in-situ observation synergies. Considering aerosol-electricity interactions, the observations will be used to improve theoretical understanding and simulations of dust lifecycle. The project will provide new fundamental understanding, able to open new horizons for weather and climate science, including biogeochemistry, volcanic ash and extraterrestrial dust research.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Greece"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["725698"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["ARISTOTELIO PANEPISTIMIO THESSALONIKIS", "ARISTOTELIO PANEPISTIMIO THESSALONIKIS", "PANEPISTIMIO THESSALIAS", "LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE", "NETHOOD"], "EU_Contribution": ["EUR 758 031"], "Project_Title": ["Refiguring the Common and the Political"], "Total_Cost": ["EUR 758 031"], "Country": ["Greece", "Greece", "Greece", "United Kingdom", "Switzerland"], "Project_ACR": ["HETEROPOLITICS"], "Technology_Description": "Heteropolitics is a project in contemporary political theory which purports to contribute to the renewal of political thought on the \u2018common\u2019 (communities and the commons) and the political in tandem. The common implies a variable interaction between differences which communicate and collaborate in and through their differences, converging partially on practices and particular pursuits. The political pertains to processes through which plural communities manage themselves in ways which enable mutual challenges, deliberation, and creative agency. ", "To": ["2020-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Greece"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other"], "From": ["2017-04-01"], "Project_ID": ["724692"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["OSPEDALE SAN RAFFAELE SRL"], "EU_Contribution": ["EUR 168 277,20"], "Project_Title": ["Investigating the effects of immunogenic chemoradiation in shaping the immune landscape ofesophageal cancers"], "Total_Cost": ["EUR 168 277,20"], "Country": ["Italy"], "Project_ACR": ["IC_IL_EC_2017"], "Technology_Description": "Esophageal carcinoma (EC) is among the top 10 deadliest cancers worldwide. The current standard therapy for ES is neoadjuvant (pre-operative) chemoradiation (NACR) followed by surgery. However, only 30% of patients achieve a complete pathological response (CPR) and long-term survival. Understanding the mechanisms of response to NACR is hence pivotal to better stratify patients and inform the design of more efficacious therapies. Evidence from some tumors suggests that NACR is \u201cimmunogenic\u201d and stimulates anti-cancer immune responses, which may contribute to the longterm effects of successful treatments. Tumor neo-antigens, generated by somatically mutated cancer genes, have been recently implicated in the activation of the most efficient anti-tumor T cell response capable of controlling tumor progression, induced by immune checkpoint blockade immunotherapy. This raises the question as to whether clinical responses induced by NACR in a fraction of ECs may be linked to the stimulation of clinically relevant T cell responses against tumor neoantigens, implying that activating tumor immunity in the non-responding ones may improve clinical responses. Objective of this proof-of-concept study is hence to address this question through the implementation of a high-throughput platform to assess neoantigen-specific T cell responses in ECs in the course of NACR.", "To": ["2020-02-29, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-SE - Society and Enterprise panel"], "Coordinated_in": ["Italy"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-03-01"], "Project_ID": ["752698"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["MEDICAL RESEARCH COUNCIL", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["The structural biology of TrkB-BDNF signalling"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["STrkB"], "Technology_Description": "Neuronal circuit development involves multiple stages that are regulated by neurotrophic factors. One of the key players, the brain-derived neurotrophic factor (BDNF), is involved in the development and functional modulation of circuits by promoting neuronal survival, synaptogenesis, synaptic transmission and synaptic plasticity. BDNF acts by binding to the tropomyosin-related kinase receptor B (TrkB), a type-I membrane protein, to trigger downstream signaling. However, the molecular architecture of this complex and the mechanism of signal propagation across the membrane remain unknown", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["709054"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["EBERHARD KARLS UNIVERSITAET TUEBINGEN", "EBERHARD KARLS UNIVERSITAET TUEBINGEN"], "EU_Contribution": ["EUR 1 499 837"], "Project_Title": ["Do early stone tools indicate a hominin ability to accumulate culture?"], "Total_Cost": ["EUR 1 499 837"], "Country": ["Germany", "Germany"], "Project_ACR": ["STONECULT"], "Technology_Description": "Cultural \u2013 not genetic \u2013 adaptations have allowed humans to colonise the planet. While discovering the roots of human culture has been described as one of the 125 most pressing scientific questions of our time (Science, 2005), it remains unclear when such forms of culture first arose in our lineage. ", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["714658"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 200 000"], "Project_Title": ["Impact of NMDA receptor diversity in sensory information processing"], "Total_Cost": ["EUR 1 200 000"], "Country": ["France", "France"], "Project_ACR": ["SensoNMDA"], "Technology_Description": "Synaptic variability between neuronal connections is thought to contribute to brain\u2019s remarkable information processing capacities. In the adult brain, the density as well as subunit composition of synaptic NMDA receptors (NMDARs) varies considerably between synapses and between neurons. Despite the well documented heterogeneity of NMDARs the functional relevance of such diversity is poorly known. In the past, the functional relevance of such NMDAR diversity has been mostly considered in the context of neuronal development and long-term synaptic plasticity. Model simulations have highlighted that dendritic computations are strongly influenced by synaptic NMDARs densities and biophysical properties. Here I propose to directly study the consequence of NMDAR diversity in shaping integration properties of single neurons in primary somatosensory cortex (S1). To achieve this I will decompose this broad question into three specific tasks. 1-Assessment of NMDAR heterogeneity in glutamatergic neurons and study how this variability shapes dendritic integration. 2-Study the impact of NMDARs in signal computation among cortical interneurons. 3-Investigate the functional relationship between endogenous NMDAR modulators and NMDAR diversity. I plan to use an array of genetic, optogenetic and pharmacological tools in combination with imaging and electrophysiological techniques to achieve the proposed objectives. Importantly, in vivo electrophysiology and two-photon imaging will be used to assess the functional relevance of NMDARs heterogeneity in single neuron computational strategies during sensory stimulation. I expect to reveal that NMDAR diversity plays a fundamental role in sensory information processing by tuning the relative recruitment of inhibitory and excitatory neurons during sensory stimuli. This work will provide an original and important data set demonstrating how NMDARs diversity provides cortical neurons with the possibility to compute complex sensory information.", "To": ["2021-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2016-12-01"], "Project_ID": ["678250"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["THE UNIVERSITY OF SHEFFIELD", "CHALMERS TEKNISKA HOEGSKOLA AB", "RANPLAN WIRELESS NETWORK DESIGN LTD", "GAPWAVES AB"], "EU_Contribution": ["EUR 877 500"], "Project_Title": ["indoor small-cell Networks with 3D MIMO Array Antennas"], "Total_Cost": ["EUR 1 309 500"], "Country": ["United Kingdom", "Sweden", "United Kingdom", "Sweden"], "Project_ACR": ["is3DMIMO"], "Technology_Description": "It is predicted that wireless network traffic will increase 1000 times in the next decade. The exponential traffic growth is not uniform across geographical areas and mainly takes place in indoor hot spots. Hence, high capacity indoor venues represent the biggest network capacity increase challenge.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["734798"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["NORSK INSTITUTT FOR LUFTFORSKNING STIFTELSE", "NORSK INSTITUTT FOR LUFTFORSKNING STIFTELSE"], "EU_Contribution": ["EUR 2 800 000"], "Project_Title": ["Camera Observation and Modelling of 4D Tracer Dispersion in the Atmosphere"], "Total_Cost": ["EUR 2 800 000"], "Country": ["Norway", "Norway"], "Project_ACR": ["COMTESSA"], "Technology_Description": "COMTESSA will push back the limits of our understanding of turbulence and plume dispersion in the atmosphere by bringing together full four-dimensional (space and time) observations of a (nearly) passive tracer (sulfur dioxide, SO2), with advanced data analysis and turbulence and dispersion modelling.", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Norway"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2015-11-01"], "Project_ID": ["670462"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["GEANT VERENIGING", "BIOBANKS AND BIOMOLECULAR RESOURCES RESEARCH INFRASTRUCTURE CONSORTIUM (BBMRI-ERIC)", "EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH", "CESNET ZAJMOVE SDRUZENI PRAVNICKYCH OSOB", "AKADEMIA GORNICZO-HUTNICZA IM. STANISLAWA STASZICA W KRAKOWIE", "DAASI INTERNATIONAL GMBH", "STICHTING EGI", "EISCAT SCIENTIFIC ASSOCIATION", "EUROPEAN MOLECULAR BIOLOGY LABORATORY", "CONSORTIUM GARR", "ETHNIKO DIKTYO EREVNAS TECHNOLOGIAS AE", "FORSCHUNGSZENTRUM JULICH GMBH", "ISTITUTO NAZIONALE DI ASTROFISICA", "INFRAFRONTIER GMBH", "INSTRUCT ACADEMIC SERVICES LIMITED", "KARLSRUHER INSTITUT FUER TECHNOLOGIE", "STICHTING LIBER", "MORAVSKA ZEMSKA KNIHOVNA V BRNE", "STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN", "INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK", "RETI SPA", "SCIENCE AND TECHNOLOGY FACILITIES COUNCIL", "SURFnet bv", "UNIVERSIDAD DE CANTABRIA", "CARDIFF UNIVERSITY"], "EU_Contribution": ["EUR 2 999 892,89"], "Project_Title": ["Authentication and Authorisation For Research and Collaboration"], "Total_Cost": ["EUR 2 999 892,89"], "Country": ["Netherlands", "Austria", "Switzerland", "Czech Republic", "Poland", "Germany", "Netherlands", "Sweden", "Germany", "Italy", "Greece", "Germany", "Italy", "Germany", "United Kingdom", "Germany", "Netherlands", "Czech Republic", "Netherlands", "Poland", "Italy", "United Kingdom", "Netherlands", "Spain", "United Kingdom"], "Project_ACR": ["AARC2"], "Technology_Description": "The goal of AARC2 is to design an AAI framework to develop interoperable AAI, to enable researchers to access the whole research and infrastructure service portfolio with one login. AARC2's objectives are:", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["EINFRA-22-2016 - User-driven e-infrastructure innovation"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Netherlands"], "Activity": ["Other", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Other", "Other", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["730941"], "Call_for_Proposal": ["H2020-EINFRA-2016-1"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6", "UNIVERSITAET PADERBORN", "UNIVERSITE DES SCIENCES ET TECHNOLOGIES DE LILLE - LILLE I", "UNIVERSITAET ROSTOCK", "UNIVERSITA DEGLI STUDI ROMA TRE"], "EU_Contribution": ["EUR 3 219 721,25"], "Project_Title": ["Quantum Controlled Ultrafast Multimode Entanglement and Measurement"], "Total_Cost": ["EUR 3 219 721,25"], "Country": ["United Kingdom", "France", "Germany", "France", "Germany", "Italy"], "Project_ACR": ["QCUMbER"], "Technology_Description": "Ultrafast light pulses offer the fascinating opportunity to study system dynamics at ultrashort time scales. Trains of ultrafast light pulses also feature a broad frequency comb structure that has been exploited e.g. in high precision metrology. These characteristics have made ultrafast optics with coherent control techniques a flourishing field in recent years. A rich toolbox has been developed to generate shorter pulses with engineered temporal and spectral properties.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-1-2014 - FET-Open research projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["665148"], "Call_for_Proposal": ["H2020-FETOPEN-2014-2015-RIA"]}, -{"Partners": ["INSTITUT FRANCAIS DES SCIENCES ET TECHNOLOGIES DES TRANSPORTS, DE L'AMENAGEMENT ET DES RESEAUX", "PHI-MECA ENGINEERING", "AALBORG UNIVERSITET", "COWI AS", "BUNDESANSTALT FUER MATERIALFORSCHUNG UND -PRUEFUNG", "GUD CONSULT GMBH", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "NEOSTRAIN SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA"], "EU_Contribution": ["EUR 3 161 112,84"], "Project_Title": ["Innovation and Networking for Fatigue and Reliability Analysis of Structures - Training forAssessment of Risk"], "Total_Cost": ["EUR 3 161 112,84"], "Country": ["France", "France", "Denmark", "Denmark", "Germany", "Germany", "Switzerland", "Poland"], "Project_ACR": ["INFRASTAR"], "Technology_Description": "INFRASTAR aims to develop knowledge, expertise and skill for optimal and reliable management of structures. The generic methodology will be applied to bridges and wind turbines in relation to fatigue offering the opportunity to deal with complementary notions (such as old and new asset management, unique and similar structures, wind and traffic actions) while addressing 3 major challenges: 1/advanced modelling of concrete fatigue behaviour, 2/new non destructive testing methods for early aged damage detection and 3/probabilistic approach of structure reliability under fatigue. Benefit of cross-experience and inter-disciplinary synergies will create new knowledge. INFRASTAR proposes innovative solutions for civil infrastructure asset management so that young scientists will acquire a high employment profile in close dialogue between industry and academic partners.", "To": ["2020-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-05-01"], "Project_ID": ["676139"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["UNIVERSITAET POTSDAM", "GCF - GLOBAL CLIMATE FORUM EV", "UNIVERSITAET STUTTGART", "INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK", "ISTITUTO PER L'INTERSCAMBIO SCIENTIFICO", "SCUOLA IMT (ISTITUZIONI, MERCATI, TECNOLOGIE) ALTI STUDI DI LUCCA", "CHALMERS TEKNISKA HOEGSKOLA AB", "ATOS SPAIN SA", "CONSORZIO TOP-IX - TORINO E PIEMONTE EXCHANGE POINT", "THE COSMO COMPANY SAS", "DIALOGIK GEMEINNUETZIGE GESELLSCHAFT FUER KOMMUNIKATIONS- UND KOOPERATIONSFORSCHUNG mbH"], "EU_Contribution": ["EUR 4 469 662,50"], "Project_Title": ["Center of Excellence for Global Systems Science"], "Total_Cost": ["EUR 4 469 662,50"], "Country": ["Germany", "Germany", "Germany", "Poland", "Italy", "Italy", "Sweden", "Spain", "Italy", "France", "Germany"], "Project_ACR": ["COEGSS"], "Technology_Description": "Global Systems Science \u2013 GSS \u2013 is an emerging research field focused on the risks and opportunities involved in global coordination problems. Examples of global systems include the internet, financial markets, intellectual property rights, global energy use and others. ", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["EINFRA-5-2015 - Centres of Excellence for computing applications"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations"], "From": ["2015-10-01"], "Project_ID": ["676547"], "Call_for_Proposal": ["H2020-EINFRA-2015-1"]}, -{"Partners": ["DEUTSCHES FORSCHUNGSZENTRUM FUR KUNSTLICHE INTELLIGENZ GMBH", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "UNIVERSITAET STUTTGART", "UNIVERSITY COLLEGE LONDON", "KOZEP-EUROPAI EGYETEM", "ISTITUTO PER L'INTERSCAMBIO SCIENTIFICO", "CONSIGLIO NAZIONALE DELLE RICERCHE", "FONDAZIONE BRUNO KESSLER"], "EU_Contribution": ["EUR 3 450 625"], "Project_Title": ["Bringing CItizens, Models and Data together in Participatory, Interactive SociaL EXploratories"], "Total_Cost": ["EUR 4 206 875"], "Country": ["Germany", "Switzerland", "Germany", "United Kingdom", "Hungary", "Italy", "Italy", "Italy"], "Project_ACR": ["CIMPLEX"], "Technology_Description": "We propose visionary research to develop modeling, computational, and ICT tools needed to predict and influence disease spread and other contagion phenomena in complex social systems. To achieve non-incremental advances we will combine large scale, realistic, data-driven models with participatory data-collection and advanced methods for Big Data analysis. In particular we will go beyond the one-dimensional focus of current approaches tackling one aspect of the problem at a time. We will interconnect contagion progression (e.g. epidemics) with social adaptation, the economic impact and other systemic aspects that will finally allow a complete analysis of the inherent systemic risk. We will develop models dealing with multiple time and length scales simultaneously, leading to the definition of new, layered computational approaches. Towards policy impact and social response we will work to close the loop between models, data, behavior and perception and develop new concepts for the explanation, visualization and interaction with data and models both on individual and on collective level. We will cast the fundamental advances into an integrated system building on widely accepted open ICT technologies that will be used and useful beyond the project. As a tangible ICT outcome directed at facilitating the uptake and impact of the project, we will implement \u201cInteractive Social Exploratories\u201d defined as interactive environments which act as a front-end to a set of parameterizable and adjustable models, data analysis techniques, visualization methods and data collection frameworks. In summary, we aim to (1) produce fundamental theoretical, methodological and technological advances (2) mold them into a broadly usable ICT platform that will be a catalyst for producing, delivering, and embedding scientific evidence into the policy and societal processes and (3) evaluate the system empirically with policy makers and citizens focusing on the concrete problem of epidemic spreading.", "To": ["2017-12-31, closed project"], "Meta": [""], "Topic_s": ["FETPROACT-1-2014 - Global Systems Science (GSS)"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Research Organisations"], "From": ["2015-01-01"], "Project_ID": ["641191"], "Call_for_Proposal": ["H2020-FETPROACT-2014"]}, -{"Partners": ["OREBRO UNIVERSITY"], "EU_Contribution": ["EUR 1 255 680"], "Project_Title": ["Training a new breed of interdisciplinary researchers to respond to the opportunities and challenges of ageing"], "Total_Cost": ["EUR 2 511 360"], "Country": ["Sweden"], "Project_ACR": ["NEWBREED"], "Technology_Description": "The ageing population is one of Europe\u2019s and the world\u2019s grand challenges for the 21st century. How to cope with populations that are living ever longer and understanding the processes and means of tackling and benefitting from such populations has already been studied in great detail. However, the studies have mostly been independent, in often almost unrelated areas. ", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2016 - Co-funding of regional, national and international programmes"], "Funding_scheme": ["MSCA-COFUND-DP - Doctoral programmes"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["754285"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2016"]}, -{"Partners": ["UNIVERSITY OF STRATHCLYDE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Models and Algorithms for Graph centrality grounded on Nonlinear Eigenvalues Techniques"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["MAGNET"], "Technology_Description": "Models and Algorithms for Graph centrality grounded on Nonlinear Eigenvalues Techniques", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["744014"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE RESEARCH COMMITTEE OF THE TECHNICAL UNIVERSITY OF CRETE", "ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON", "TECHNOLOGIKO PANEPISTIMIO KYPROU", "THE CYPRUS INSTITUTE", "AEA s.r.l.", "THE UK INTELLIGENT SYSTEMS RESEARCH INSTITUTE LIMITED", "Elgama-Elektronika", "IDEA SRL", "BRUNEL UNIVERSITY LONDON", "EXERGY LTD"], "EU_Contribution": ["EUR 958 500"], "Project_Title": ["Smart Grids Energy management Staff"], "Total_Cost": ["EUR 958 500"], "Country": ["Greece", "Greece", "Cyprus", "Cyprus", "Italy", "United Kingdom", "Lithuania", "Italy", "United Kingdom", "United Kingdom"], "Project_ACR": ["SMART GEMS"], "Technology_Description": "Smart grid is a dynamically interactive real-time infrastructure concept that encompasses the many visions of diverse energy system stakeholders. The Smart Grid is integrating the electrical and information technologies in between any point of generation and any point of consumption. The main objective of the project is to fully analyze all aspects of smart grids targeting in the improvement of reliability, mitigation of security risks, increase load shaping and energy efficiency, optimal integration and generation-consumption matching as well as smart monitoring and control.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Greece"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-09-01"], "Project_ID": ["645677"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["THE RESEARCH COMMITTEE OF THE TECHNICAL UNIVERSITY OF CRETE"], "EU_Contribution": ["EUR 152 653,20"], "Project_Title": ["PArtial Differential Equation model-based COntrol of Traffic flow"], "Total_Cost": ["EUR 152 653,20"], "Country": ["Greece"], "Project_ACR": ["PADECOT"], "Technology_Description": "A new framework is introduced for control and estimation of traffic flow in freeways and arterials. In the new methodology, feedforward and feedback control designs are developed, based on continuum in time and space traffic-flow models, which assign to the traffic flow the desired shape, with an a priori prescribed convergence rate and for any initial traffic profile. The novel control and estimation algorithms require minimum amount of information since they utilize measurements at the entries and exits of the freeway and arterial links. The designs are accompanied with tools for verification that are introduced, which provide quantified actual performance guarantees and robustness margins of the proposed algorithms. The methodology is validated in simulation, using fictitious and real data of traffic, and/or in a real traffic system.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Greece"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["747898"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF LEEDS"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Ti-Graphene Bone Tissue Template Engineering"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["BonE-GraphT"], "Technology_Description": "The BonE-GraphT aims to develop a new approach, based on bone template engineering using which the entire load-bearing structure might be possible to regenerate for replacing the damaged bone. The proposed approach, once developed, will be possible to align with the tissue-engineering bio-reactor technology for in-theatre use, which may be able to meet the demand for current shortage in treating the damaged load-bearing long bones (e.g. tibia femur) in trauma, osteoporotic bones and other bone defects. Within my research I am going to develop a new biomaterial: Calcium Phosphate coated graphene composite on porous Ti-alloy substrate via pulsed laser deposition techniques for enabling biocompatibility via osteoconductive process, promoted via progenitor stem cells. For research training as an orthopaedic materials engineer within which I aim to solve orthopaedic defects as a global problem I will deal with the following Research Training Activities (RTAs); i) Ti-alloy based graphene/calcium phosphate materials processing using femtosecond PLD; ii) Characterization of bio-active materials surface; iii) Characterization of cell cultivation, toxicity, attachment and mineralization; iv) Design of model bone structure.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["752297"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER", "WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER", "FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG"], "EU_Contribution": ["EUR 1 499 875"], "Project_Title": ["Structure-Property Relations in Aqueous Foam and Their Control on a Molecular Level"], "Total_Cost": ["EUR 1 499 875"], "Country": ["Germany", "Germany", "Germany"], "Project_ACR": ["SUPERFOAM"], "Technology_Description": "Foams are of enormous importance as we find them in many technological relevant applications and food products. Foams as hierarchical materials are dominated by the arrangement and distri-bution of gas bubbles on a macroscopic scale, as well as by thickness and composition of lamella on a mesoscopic scale. Liquid-gas interfaces are, however, the building block of foam with over-whelming importance as their molecular properties easily dominate hierarchical elements on larger length scales. In order to formulate foam with specific properties, its structure must be controlled at the molecular level of a liquid-gas interface. Here, the molecular composition, molecular order and interactions such as electrostatics dominate, and thus must be addressed with molecular level probes that can provide access to both interfacial solvent and solute molecules. Specifically, mo-lecular structures of aqueous interfaces can be modified by adding different mixtures of surface active molecules such as proteins, surfactants and polyelectrolytes, and by adjusting electrolyte properties. This is achieved by varying pH, introducing ions at different ionic strengths as well as by changing viscosities. Such model systems will be characterized with nonlinear optical spectroscopy amongst other surface sensitive probes. The gained information will be used to deduce properties of structures on larger length scales such as lamella, bubbles in a bulk liquid - as a precursor of foam - and finally macroscopic foam. For each length scale, experiments will be performed to gain access to molecular buildings blocks at liquid-gas interfaces and their effects on other hierarchical elements. These experiments thus provide essential information on foam stability and bubble coalescence, they can be used to verify structure-property relationships and to advance our understanding of foam on a molecular basis.", "To": ["2020-02-29, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-03-01"], "Project_ID": ["638278"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["UNIVERSITY OF SURREY"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Vulnerability and risk assessment of transportation systems of assets (SoA) exposed to geo-hazards"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["TRANSRISK"], "Technology_Description": "Available risk assessment frameworks typically consider individual assets of the transportation infrastructure, exposed to just one hazard and they neglect changes in the asset performance during its life. However, assets exist in systems (SoA) and they are usually exposed to multiple hazards, whilst their performance changes due to deterioration or improvements. Also, the vast majority of existing studies is qualitative and focuses on bridges. Hazards, such as ground movements, debris flow, earthquakes and floods are major threats to infrastructure around the world, causing significant physical and socio-economic losses. Thus, reliable assessment of the vulnerability and the associated risks of infrastructure subjected to critical hazards is of paramount importance toward resilient transportation networks. TRANSRISK aims to fill these acknowledged gaps and provide advanced vulnerability assessment of critical transportation SoA subjected to diverse geo- and climatic hazards with focus on geotechnical effects, taking into account the SoA performance changes during their life. In this context, advanced numerical models of representative SoA subjected to critical combinations of hazard effects will be generated and validated based on recorded events. Novel adaptable vulnerability models will be produced for as-built, deteriorated (e.g. past hazards) and improved (e.g. strengthened) SoA. These models will be applied to selected parts of a highway and/or railway network in Europe to estimate the risk and associated losses due to recorded hazards as a means to enable the unbiased allocation of resources in decision-making and disaster management. The research results will provide a better understanding of the response of critical SoA and a rational link of the individual asset response to the network performance. The outcomes will also benefit stakeholders and owners of transportation networks in line with the EU strategy on critical infrastructure protection.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["746298"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE RESEARCH COMMITTEE OF THE TECHNICAL UNIVERSITY OF CRETE"], "EU_Contribution": ["EUR 164 653,20"], "Project_Title": ["Enhancing our Understanding of Earth\u2019s Land Surface InteractiONs at Multiple Scales Utilising Earth Observation"], "Total_Cost": ["EUR 164 653,20"], "Country": ["Greece"], "Project_ACR": ["ENviSION-EO"], "Technology_Description": "\"Today, particularly so in the face of climate change and the need to meet global food and water security requirements, there is an urgent need for a better understanding of natural processes in the Earth System and of land surface interactions (LSIs). The recent rapid developments in Earth Observation (EO) technology (new satellites launched, drones) demonstrate the real need and the true potential of this technology in this direction. ", "To": ["2019-10-01, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Greece"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-02"], "Project_ID": ["752094"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE", "INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Treatment of liver disease and cancer prevention"], "Total_Cost": ["EUR 150 000"], "Country": ["France", "France"], "Project_ACR": ["PRELICAN"], "Technology_Description": "Advanced liver disease and cancer is the only major cause of death still increasing each year. Major causes include hepatitis B and C viruses, alcohol and non-alcoholic fatty liver disease/steatohepatitis (NAFLD/NASH). A major contributing factor to the increasing incidence and mortality of liver disease is the staggering rise in obesity. The absence of effective therapeutic options for NAFLD/NASH, advanced liver disease and cancer contribute to the poor prognosis and the high cost associated with patient care. We have established a tractable and clinically relevant human cell-based model system in which viral infection, ethanol or free fatty acids induce a clinical gene expression signature robustly predicting liver disease progression and long-term HCC risk in cirrhotic patients. Using this model we identified compounds as HCC chemopreventive agents. Aiming to evaluate these compounds for future clinical development and potential commercialization we will perform proof-of-concept studies in state-of-the-art mouse models for NASH and hepatocarcinogenesis. Specifically we will assess the therapeutic effect on liver inflammation, steatosis, fibrosis and HCC development and investigate its safety in long-term administration. With the completion of this program we expect to obtain a robust proof-of-concept data package as a first- or best-in-class compound for treatment of chronic liver disease and prevention of HCC.", "To": ["2018-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-06-01"], "Project_ID": ["755460"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["UNIVERSITE DE PERPIGNAN"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Study of the environmental impact of insecticides by metabolomic foot-printing approach"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["EnvFate"], "Technology_Description": "The European Directive in 1998 led to the increasing use of biological insecticides such as cry proteins produced by the bacterium Bacillus thuringiensis israelensis (Bti) that kill mosquito larvae after being ingested. Considering the interest in Bti as more environmentally sustainable biocide, it is important to examine environmental fate and impact of Bti especially taking into account the need of this information to fulfil the REACH criteria. Chandrashekhar (PhD 2014, North Maharashtra University, India) will employed an innovative 'Environmental Metabolic Footprinting' approach, at the University of Perpignan via Domitia, France and participate in a multidisciplinary project that spans the interface between chemistry and biology. To dynamically characterize biomarkers of Bti pollution found among metabolites issued from the sediment matrix meta-metabolome will require him to develop and optimize detection protocols using LC-MS platform. In addition, metabarcoding approach will allow to understand microbial community responses to the Bti pollution. Emphasis will be placed on better standardisation, data interpretation and evaluation that will build confidence in the value of \u201comics technologies \u2013 this being essential to increase their (regulatory) use. Through secondment to University Joseph Fourier, Grenoble he will deepen his knowledge base by evaluating fate of Bti in the sediment through cutting edge biological analysis tools. Taken together, these activities will advance our understanding of environmental risks associated with Bti, and pave the way for the development and adaptation to new environmental monitoring tool. EnvFate will thus increase the European research visibility to promote sustainable development, ensure the protection of environment, one of the priority areas of the H2020 program. Moreover, through the planned training and mentoring activities, Chandrashekhar will develop in to an outstanding early career researcher of great potential.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["746656"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSIDAD DE SALAMANCA"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Role of bacterial cellulases in the transition from free living to root endophytes in rapeseed crops and in the design of efficient biofertilizers"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["BIOFERTICELLULASER"], "Technology_Description": "One of the main challenges for humanity during next decades will be to increase food production while using scarce resources and protecting the environment, being therefore one of the priorities of the European Program \u201cHorizon 2020\u201d. Plant\u2019s productivity can be enhanced by the activity of Plant Growth-Promoting (PGP) bacteria, applied in agricultural fields as biofertilizers or plant probiotics, constituting an environmental friendly manner to increase crop yields. Biofertilizers have been applied in agriculture during decades, but in many cases bacteria which showed great PGP potential in lab conditions, fail when applied in natural soils, probably because they are out-competed by the soil native microbial populations or they are unable to adapt to the new environmental conditions.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["750795"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KING'S COLLEGE LONDON"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Legal Cultures and Literary Trials in the Age of Goethe. The Vehmic Court Motif in Interdisciplinary and Comparative Perspective"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["VehmeLit"], "Technology_Description": "The project aims at a first systematic and in-depth investigation of the motif of the Vehmic Court \u2013 a medieval secret tribunal \u2013 in German literature of the late 18th and early 19th centuries. Despite the remarkable popularity of the subject, little research has yet been conducted to define the epistemological framework of its development. By dismissing the Vehme as a \u201ctrivial\u201d trope, scholars have not grasped its broader relevance for the culture of the Saddle Period around 1800, an age of transitions and paradigm shifts in society and politics, but also in literature, historiography and the legal system.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["744413"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["INSTITUT CURIE", "INSTITUT CURIE"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Precision confiner for mechanical cell activation"], "Total_Cost": ["EUR 150 000"], "Country": ["France", "France"], "Project_ACR": ["ACTICELL"], "Technology_Description": "In tissues, cells have their physical space constrained by neighbouring cells and extracellular matrix. In the PROMICO ERC project, our team proposed to specifically address the effect of physical confinement on normal and cancer cells that are dividing and migrating, using new pathophysiologically relevant in vitro approaches based on innovative micro-fabrication techniques. One of the devices we developed was meant to quantitatively control two key parameters of the cell environment: its geometry and its surface chemical properties. The main technical breakthrough was achieved using micro-fabricated elastomeric structures bound to a hard substrate (Le Berre Integrative Biology, 2012). The method led to important fundamental discoveries in cell biology (Lancaster Dev Cell 2013, Le Berre PRL 2013, Liu Cell 2015, Raab Science 2016). In part based on our findings, the notion that confinement is a crucial parameter for cell physiology has spread through the cell biology. Based on this, our idea is that cell confinement could be used as a powerfull cell conditioning technology, to change the cell state and offer new opportunities for fundamental research in cell biology, but also in cell therapies and drug screening. However, our current method to confine cells is not adapted to large scale cell conditioning applications, because the throughput and reliability of the device is still too low and because the recovery of cells after confinement remain poorly controlled. It is thus now timely to develop a robust and versatile cell confiner adapted to use in any cell biology lab, in academy and in industry, with no prior experience in micro-fabrication. Achieving this goal involves a complete change of technology compared to the \u2018homemade\u2019 PDMS device we have been using so far. We will also perform proofs of concept of its use for its application in cell based therapies, such as cancer immunotherapy, by testing the possibility to mechanically activate dendritic cells.", "To": ["2018-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-06-01"], "Project_ID": ["755347"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["EUROPEAN MOLECULAR BIOLOGY LABORATORY", "EUROPEAN MOLECULAR BIOLOGY LABORATORY"], "EU_Contribution": ["EUR 2 499 995"], "Project_Title": ["Dissecting quantitative traits and their underlying genetic interactions via systematic genome editing"], "Total_Cost": ["EUR 2 499 995"], "Country": ["Germany", "Germany"], "Project_ACR": ["SystGeneEdit"], "Technology_Description": "Despite the ubiquity of genome sequence data, unravelling the contributions of genetic variation to phenotypic diversity remains one of the greatest challenges in genomics. This is partly due to our very limited knowledge of how multiple variations combine to create phenotypes. There is a clear need for a systematic, perturbation-based approach to study the phenotypic consequences of genetic variants in different genomic and environmental contexts. Previous efforts have primarily used loss-of-function or overexpression approaches, but it is known that subtle, naturally occurring variants have the most relevance for complex, quantitative traits. Our proposal aims to dissect these effects by systematically engineering and functionally profiling naturally occurring single-nucleotide variants (SNVs) and small insertion/deletion polymorphisms (indels) in the S. cerevisiae species in three diverse genetic backgrounds. To generate such an unprecedented collection, we will apply a high-throughput CRISPR approach that allows rapid isolation of sequence-verified strains. DNA barcodes integrated into the genome of each strain will enable pooled, competitive growth, which will reveal how variants modulate fitness as a function of environment and genetic background. We will test our collection for pairwise and higher order interactions, assay their impact on cellular processes and dissect pleiotropic roles of highly connected genes. Our work will circumvent the key limitations in current high-throughput genome editing screens and enable the largest interrogation of the functional impact of genetic variation in different environmental and genetic contexts to date. The combined insights and tools generated by our work will aid in developing predictive models of the effects of genetic variation within specific environmental and biological contexts, providing guiding principles for understanding the consequences of human genetic variation.", "To": ["2022-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-11-01"], "Project_ID": ["742804"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM", "INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM"], "EU_Contribution": ["EUR 2 499 074"], "Project_Title": ["video-rate holographic projection by novel meta-materials"], "Total_Cost": ["EUR 2 499 074"], "Country": ["Belgium", "Belgium"], "Project_ACR": ["VIDEO HOLOGRAPHY"], "Technology_Description": "Today, despite many efforts by researchers world-wide, there are no holographic projectors that allow video-rate electronically controlled projection of complex holograms. Optically re-write-able holograms exist, but they are too slow; Acoustically-formed holograms can be switched fast but the image complexity is very limited. We identify the essential roadblock as one that we intend to clear by a breakthrough innovation coming from a combination of electronics, optics and material science. ", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Belgium"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-10-01"], "Project_ID": ["742299"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOCIENCIAS", "ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOCIENCIAS"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["A metabolism-based prognostic biomarker for prostate cancer"], "Total_Cost": ["EUR 150 000"], "Country": ["Spain", "Spain"], "Project_ACR": ["MetaboMARKER"], "Technology_Description": "Prostate cancer (PC) is the most prevalent tumour type among men. The fraction of patients that exhibit disease recurrence can reach 15% and they face an uncertain future, since this type of tumour is prone to resist to subsequent therapeutic strategies. Current guidelines for treatment of PC include prostatectomy or radiotherapy as first line therapy for localized disease, and chemical castration followed by chemotherapy for recurrent PC. The lack of capacity to identify therapy responders vs. escapers in PC is one of the sources for its important mortality. The challenge resides in providing clinicians with a robust and affordable biomarker that informs about the success of first line therapy in localised PC, and that allows them to employ more intensive therapeutic strategies in high-risk patients.", "To": ["2018-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-06-01"], "Project_ID": ["754627"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["GOETEBORGS UNIVERSITET", "GOETEBORGS UNIVERSITET"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Ultrafast Molecular Structural Dynamics"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["MolStrucDyn"], "Technology_Description": "Chemical reactions in solution are strongly influenced by femtosecond solvent-solute dynamics. Likewise, proteins provide specific environments to control the outcome of substrate reactions. The molecular understanding of these effect are currently poorly developed. ", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["725642"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN", "RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN"], "EU_Contribution": ["EUR 1 277 830"], "Project_Title": ["A Unified Framework of Business Cycles and Household Portfolios: Income Risks, Asset Liquidity, and Inequality"], "Total_Cost": ["EUR 1 277 830"], "Country": ["Germany", "Germany"], "Project_ACR": ["LiquidHouseCycle"], "Technology_Description": "Households face large idiosyncratic income risks and use their wealth to self insure. In doing so, they make portfolio choices we can summarize grosso modo as choices between liquid (safe and nominal) and illiquid (risky and real) assets. These choices have the potential to create strong aggregate repercussions as investments in real assets create an immediate demand for goods, while liquid nominal savings only when someone else uses the funds to invest or consume. As a result, portfolio choices are key for economic dynamics and important for the propagation of monetary and fiscal policy. Moreover, household portfolio positions and the liquidity of assets itself become an important determinant of aggregate savings and investment. Yet, they are widely disregarded in standard business cycle models today.", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["724204"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITAET INNSBRUCK", "UNIVERSITAET INNSBRUCK", "LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN"], "EU_Contribution": ["EUR 1 496 664,30"], "Project_Title": ["Innovative Strategies towards Halogenated Organic Molecules: From Reaction Design to Application in Drug Synthesis"], "Total_Cost": ["EUR 1 496 664,30"], "Country": ["Austria", "Austria", "Germany"], "Project_ACR": ["HALODRUGSYN"], "Technology_Description": "Halogenated arenes and heteroarenes have become essential structural motifs of the pharmaceutical industry to create novel drugs against bacterial infections and cancer, and constitute highly valuable functional units in chemistry. Current methods for the installation of carbon-halogen bonds lack efficiency, selectivity, and practicability within the complex molecular setting of drug development processes. These restrictions prevent many potential drugs from being synthesized in a time- and cost-efficient manner.", "To": ["2022-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-02-01"], "Project_ID": ["714049"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["HEINRICH-HEINE-UNIVERSITAET DUESSELDORF", "HEINRICH-HEINE-UNIVERSITAET DUESSELDORF"], "EU_Contribution": ["EUR 1 920 697"], "Project_Title": ["Control of amyloid formation via beta-hairpin molecular recognition features"], "Total_Cost": ["EUR 1 920 697"], "Country": ["Germany", "Germany"], "Project_ACR": ["BETACONTROL"], "Technology_Description": "The aggregation of proteins into amyloid fibrils is involved in various diseases which place a high burden on patients, families, caregivers, and healthcare systems, including Alzheimer\u2019s disease, Parkinson\u2019s disease and type 2 diabetes. While the therapeutic potential of the inhibition of amyloid formation and spreading has been recognized, there is a lack of effective strategies targeting the early steps of the aggregation reaction.", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["726368"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["FONDATION POUR L INSTITUT DE HAUTES ETUDES INTERNATIONALES ET DU DEVELOPPEMENT", "FONDATION POUR L INSTITUT DE HAUTES ETUDES INTERNATIONALES ET DU DEVELOPPEMENT"], "EU_Contribution": ["EUR 2 475 275"], "Project_Title": ["The Paths of International Law: Stability and Change in the International Legal Order"], "Total_Cost": ["EUR 2 475 275"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["PATHS"], "Technology_Description": "International law erects high hurdles for change \u2013 typically unanimity or a uniformity of practice of states \u2013 and this high threshold has provoked much criticism for hindering the pursuit of justice, the provision of public goods, and the democratic revision of political choices. Yet in different areas, such as international criminal law or the law of international organizations, international law has in recent times undergone more rapid change than the traditional picture would allow, and often in informal ways that do not fit classical categories. However, this greater dynamism has found little sustained attention in scholarship so far. ", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["740634"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH", "UNIVERSITE CATHOLIQUE DE LOUVAIN", "ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON", "INSTITUT FUR PFLANZENKULTUR EK", "ARISTOTELIO PANEPISTIMIO THESSALONIKIS", "UNIVERSITEIT GENT"], "EU_Contribution": ["EUR 2 732 872,32"], "Project_Title": ["\u201cMICROMETABOLITE\u201d \u2013 Research Training Network on the Microbial Enhancement of Bioactive Secondary Metabolite Production in Plants"], "Total_Cost": ["EUR 2 732 872,32"], "Country": ["Austria", "Belgium", "Greece", "Germany", "Greece", "Belgium"], "Project_ACR": ["MICROMETABOLITE"], "Technology_Description": "Plant-derived natural products or, more specifically, plant secondary metabolites are backbones of today\u2019s pharmaceutical and cosmeceutical industry. Plant-associated microorganisms have been implicated an important role in sustaining plant growth and, through inducing or influencing synthesis pathways, in the production of plant secondary metabolites. MICROMETABOLITE aims at exploring the plant-associated microflora for improving the production of bioactive secondary plant metabolites that are of high value for industrial applications. The network will focus on members of the Boraginaceae plant family including Lithospermum and Alkanna species, which produce the naphtoquinones shikonin and alkannin derivatives (A/S). These plants are used for the production of several pharmaceutical and cosmeceutical preparations that are already on the market or in the final stages of development. Specifically, we will analyse relationships between the content of A/S or other secondary metabolites, the plant genotype, and the plant-associated microflora. Further, we will explore in which ways microorganisms beneficially influence metabolite production, and we will establish novel production systems, enabling that raw materials for industrial applications can be cultivated under Good Agricultural Practices (GAP).", "To": ["2021-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Austria"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["721635"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["FONDATION POUR L INSTITUT DE HAUTES ETUDES INTERNATIONALES ET DU DEVELOPPEMENT"], "EU_Contribution": ["EUR 117 137,25"], "Project_Title": ["Women's Economic Rights and Cultural Difference: Defining Development for the Middle East"], "Total_Cost": ["EUR 117 137,25"], "Country": ["Switzerland"], "Project_ACR": ["WoRD-DoME"], "Technology_Description": "This research focuses on tensions between discourses of multiculturalism and women\u2019s economic rights and the processes in which they arise in development institutions and programs. While the multidisciplinary literature on development unpacks public declarations by development institutions and studies the local implementation of development programs, it evades two crucial questions: conditions of agency formation and inequality in institutional processes, and the role assumptions about cultural difference play in development paradigms. This research fills these gaps by exploring how issues of women\u2019s economic rights and notions of cultural difference are negotiated inside development institutions and reflected in their programs. The research deploys two data collection strategies, longitudinal content and discourse analysis of relevant development reports and interviews with gender experts with work experience on the Middle East. It will be conducted at the Gender Centre of the Graduate Institute of International and Development Studies, under the supervision of Professor Elisabeth Pr\u00fcgl, a best fit for the project given the rich array of gender and development scholarship at the Centre, its established networks with the multilateral actors in Geneva and beyond, and the two scholars\u2019 mutual interests in the area of gender expertise and gender equality. It is an interdisciplinary project, informed by relevant studies in the fields of anthropology, sociology and political science, and has significant potential to contribute development studies and feminist political economy. It builds on the researcher\u2019s experience in the field of gender and development, the Middle East and transnational networks. It expands her research to international gender experts in development; grows her expertise on the Middle East; and enlarges her fieldwork scope to Europe. The training, networking and publication prospects put her on a firm path toward professorship.", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["746133"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAETSKLINIKUM HAMBURG-EPPENDORF"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Vision at a second glance - how memories interact with and depend on information processing in the human visual cortex"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["VisionAtSecondGlance"], "Technology_Description": "The cognitive faculties of memory and vision are heavily intertwined. Therefore, understanding the brain processes supporting these faculties critically depends on insights into vision-memory interactions.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["753441"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE", "INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE"], "EU_Contribution": ["EUR 1 965 624,99"], "Project_Title": ["Directed crop breeding using jumping genes"], "Total_Cost": ["EUR 1 965 624,99"], "Country": ["France", "France"], "Project_ACR": ["BUNGEE"], "Technology_Description": "The rapidly changing climate puts commonly used crop plants under strong pressure. It is therefore essential to develop novel breeding technologies to rapidly enhance crops to better withstand newly emerging stresses.", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-06-01"], "Project_ID": ["725701"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["THE RESEARCH COMMITTEE OF THE TECHNICAL UNIVERSITY OF CRETE", "MASSACHUSETTS INSTITUTE OF TECHNOLOGY"], "EU_Contribution": ["EUR 176 408,10"], "Project_Title": ["Mechanistic Microscale Approach to the Microbial Degradation of Oil-Droplets in Subsea Crude Oil Releases"], "Total_Cost": ["EUR 176 408,10"], "Country": ["Greece", "United States"], "Project_ACR": ["OILY MICROCOSM"], "Technology_Description": "In oligotrophic marine ecosystems, the natural or accidental release of crude oil marks the beginning of a season of feast for indigenous microbial consortia that have developed appropriate adaptive machinery to access and assimilate hydrocarbons. Biodegradation and bioemulsification are among the key processes by which marine microbes strongly affect the transport and fate of crude oil in the sea. Unraveling of the coupled physical and biochemical interactions between microbes and oil droplets will be a major enabler for achieving a new level of prediction of crude oil dispersion as well as for developing more efficient bioremediation techniques to combat oil spills in marine environments. The proposed research project aims at an improved understanding of the fundamental microscale mechanisms that underpin oil biodegradation with a highly innovative focus at both the single-droplet and droplet-population levels. In particular, at the single-droplet level, our focus is on the droplet-microbe interactions and the dynamics of biofilm formation over the oily substrate. Ultimately, the developing interfaces between biofilms, oil and water will be tracked and quantitatively visualized. At the droplet-population level, our focus is on the evolution of the droplet size distribution (DSD) and its impact on the average biodegradation rates for a cloud of oil microdroplets (10-60 um). The research methodology is based on a creative combination of state-of-the-art microfluidics, biochemical analyses and computational modeling. All in all, this project is expected to provide a unique and original approach to a fundamental problem in microbial ecology that has wide societal and economical repercussions. Importantly, a profound impetus will be given to the Researcher\u2019s career via strengthening his publication record and his professional network of contacts.", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Greece"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["741799"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN", "LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN"], "EU_Contribution": ["EUR 1 525 925"], "Project_Title": ["Small animal proton Irradiator for Research in Molecular Image-guided radiation-Oncology"], "Total_Cost": ["EUR 1 525 925"], "Country": ["Germany", "Germany"], "Project_ACR": ["SIRMIO"], "Technology_Description": "Precision small animal radiotherapy (RT) research is a young emerging field aiming at unravelling complex in-vivo mechanisms of radiation damage in target and non-target tissues, for translation into improved clinical treatment strategies.", "To": ["2021-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["725539"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["CONSIGLIO NAZIONALE DELLE RICERCHE", "CONSIGLIO NAZIONALE DELLE RICERCHE"], "EU_Contribution": ["EUR 1 880 060"], "Project_Title": ["Full-scale COmputational design of Porous mesoscale MATerials"], "Total_Cost": ["EUR 1 880 060"], "Country": ["Italy", "Italy"], "Project_ACR": ["COPMAT"], "Technology_Description": "The last decades have witnessed major progress in our understanding of the basic physics of soft matter materials. At the same time, microfluidics has also undergone spectacular theoretical and experimental progress. The confluence of such major advances spawns unprecedented opportunities for the design and manufacturing of new soft mesoscale materials, with promising applications in tissue engineering, photonics, catalysis and many others. COPMAT is targeted at making the most this opportunity through the pursuit of a single general goal: the full-scale simulation at nanometric resolution of micro-reactors for the design and synthesis of new tunable porous materials. In particular, we shall focus on the microfluidic design of: multi-jel materials, trabecular porous media and soft mesoscale molecules. We shall also explore new designs concepts based on unexplored microscale phenomena, such as the interaction between plasticity and nano-rugosity. The complex interplay between the highly non-linear rheology of soft materials and the major experimental control parameters leads to an engineering design of formidable complexity, characterized by a strong sensitivity of the macroscale material properties on the details of nanoscale interfacial interactions. COPMAT will tackle this formidable multiscale challenge through the deployment of an entirely new family of multiscale techniques, centered upon highly innovative extensions of the Lattice Boltzmann method and its combinations with Immersed Boundary Method, Dissipative Particle Dynamics and Dissipative Voronoi Dynamics. The success of COPMAT will be gauged by its capability of inspiring and realizing the design of microfluidic devices for the synthesis of novel families of porous materials for bio-engineering applications. The new paradigm established by COPMAT for the computational design of soft materials is expected to extend well beyond the time-horizon of the project.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-10-01"], "Project_ID": ["739964"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN", "LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Age-dependent Regulation of Dendritic Cell Development and Function"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["Baby DCs"], "Technology_Description": "Early life immune balance is essential for survival and establishment of healthy immunity in later life. We aim to define how age-dependent regulation of dendritic cell (DC) development contributes to this crucial immune balance. DCs are versatile controllers of immunity that in neonates are qualitatively distinct from adults. Why such age-dependent differences exist is unclear but newborn DCs are considered underdeveloped and functionally immature. ", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["715182"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["UNIVERSITAT AUTONOMA DE BARCELONA"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Reactivation of the Fanconi anemia-BRCA pathway in cells carrying patient-derived missense mutations: finding a drug to cure Fanconi anemia"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["FANCODRUG"], "Technology_Description": "Fanconi anemia (FA) is a genetic disease characterized by bone marrow failure, malformations and cancer predisposition. Currently, there is no cure for FA and life expectancy is 29 years. In addition, FA cells are hypersensitive to DNA coss-linking agents used in chemotherapy making cancer treatment difficult. The genetic cause of FA is heterogeneous, involving at least 19 different FA genes (FANCA, B, C, D1/BRCA2, D2, E, F, G, I, J, L, M, N, O, P, Q, R, S/BRCA1 and T) all interacting in a common DNA repair pathway (the FA/BRCA pathway). FANCD2 ubiquitination and localization at sites of DNA damage is a key step in the activation of the FA pathway and it is used to assess its functionality. Importantly, mutations in FANCA are the most prevalent, accounting for 60-85% of FA cases. FANCA missense mutants mislocalize FANCA to the cytoplasm instead of the nucleus, thereby inactivating the FA pathway. However, FANCA mutants may retain its functionality, suggesting that correction of the subcellular mislocalization of FANCA missense mutants may be an effective way to reactivate the FA/BRCA pathway in these patients. In this application, we propose to conduct a study to develop a system to promote nuclear localization of FANCA missense mutants and evaluate its impact on the activation of the FA/BRCA pathway. This study will yield valuable information about the molecular mechanisms that determine FANCA subcellular localization and pathogenicity of the mutations. In a second part of the project, we will use an unbiased high-throughput approach to screen for drugs that can reactivate the FA/BRCA pathway in cells containing FANCA missense mutations, independently of their mechanism of action. In summary, using a combination of targeted and unbiased approaches, we aim at finding the first drug with the potential to cure FA in a large subset of patients. Personalized medicine-based therapies may be the only option to cure FA and other highly heterogeneous genetic diseases.", "To": ["2019-03-06, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-03-07"], "Project_ID": ["703521"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["FUNDACIO INSTITUT CATALA DE NANOCIENCIA I NANOTECNOLOGIA"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Complex photon-phonon coupling"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["COPPOLa"], "Technology_Description": "When humans design devices to perform a given functionality, we often prioritize ordered patterns and symmetry over anything else. Optomechanics is a clear example where precisely fabricated nanometer-scale devices are required to interface efficiently light with the mechanical vibrations of matter at the nanoscale. This coupling provides an extra degree of freedom to control the light-matter interaction. In state-of-the art optomechanical crystals, unavoidable fabrication imperfections impose severe performance limits increasing the energy dissipation and hampering their optical and mechanical performance.", "To": ["2018-05-31, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2016-06-01"], "Project_ID": ["701590"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE", "ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE", "UNIVERSITY OF BRISTOL", "QUEEN MARY UNIVERSITY OF LONDON", "UNIVERSITY OF LEEDS", "UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 1 422 010,20"], "Project_Title": ["Honeybee communication: animal social learning at the height of social complexity"], "Total_Cost": ["EUR 1 422 010,20"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom", "United Kingdom", "United Kingdom", "United Kingdom"], "Project_ACR": ["BeeDanceGap"], "Technology_Description": "Learning from others is fundamental to ecological success across the animal kingdom, but a key theme to emerge from recent research is that individuals respond differently to social information. Understanding this diversity is an imposing challenge, because it is hard to replicate the overwhelming complexity of free-living groups within controlled laboratory conditions. Yet here I propose that one of the most complex social models that we know of\u2014 the sophisticated eusocial societies of honeybees\u2014 offer unrivaled and yet unrecognized potential to study social information flow through a natural group. The honeybee \u201cdance language\u201d is one of the most celebrated communication systems in the animal world, and central to a powerful information network that drives our most high-profile pollinator to food, but bee colonies are uniquely tractable for two reasons. Firstly, next-generation transcriptomics could allow us to delve deep into this complexity at the molecular level, on a scale that is simply not available in vertebrate social systems. I propose to track information flow through a natural group using brain gene expression profiles, to understand how dances elicit learning in the bee brain. Secondly, although bee foraging ranges are vast and diverse, social learning takes place in one centralized location (the hive). The social sciences now offer powerful new tools to analyze social networks, and I will use a cutting-edge network-based modelling approach to understand how the importance of social learning mechanisms shifts with ecology. In the face of global pollinator decline, understanding the contribution of foraging drivers to colony success has never been more pressing, but the importance of the dance language reaches far beyond food security concerns. This research integrates proximate and ultimate perspectives to produce a comprehensive, multi-disciplinary program; a high-risk, high-gain journey into new territory for understanding animal communication.", "To": ["2021-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-02-01"], "Project_ID": ["638873"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON", "UNIVERSITAET DUISBURG-ESSEN", "DANMARKS TEKNISKE UNIVERSITET", "INSTITUT POLYTECHNIQUE DE GRENOBLE", "UNIVERSIDAD CARLOS III DE MADRID", "UNIVERSITY OF CYPRUS", "UNIVERZA V LJUBLJANI", "BUDAPESTI MUSZAKI ES GAZDASAGTUDOMANYI EGYETEM", "CONSORZIO NAZIONALE INTERUNIVERSITARIO PER LE TELECOMUNICAZIONI", "III-V LAB"], "EU_Contribution": ["EUR 3 867 896,88"], "Project_Title": ["FIber-Wireless Integrated Networks for 5th Generation delivery."], "Total_Cost": ["EUR 3 867 896,88"], "Country": ["United Kingdom", "Germany", "Denmark", "France", "Spain", "Cyprus", "Slovenia", "Hungary", "Italy", "France"], "Project_ACR": ["FIWIN5G"], "Technology_Description": "This European Training Network aims to produce the next generation of early stage researchers who will enable Europe to take a leading role in the development of future devices, systems and networks supporting the 5G high-speed wireless internet. To do this, researchers must be able to work in interdisciplinary teams, integrate their activities, share expertise, and promote a vision of a converged wireless and optical devices and networks that efficiently supports the services and applications being demanded. A large number of technologies and devices will need to converge, co-exist and interoperate, and most importantly, cooperate, if this vision is to be efficiently and cost-effectively realised. A key area within this next generation jigsaw is the integration of optical fibre networks and radio networks at mm-wave frequencies, to provide high-bandwidth front/backhaul services and enable scalable and manageable networks without a highly complex interface structure and multiple overlaid protocols.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2015-01-01"], "Project_ID": ["642355"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE"], "EU_Contribution": ["EUR 146 591,10"], "Project_Title": ["\u2018The re-privatization of the contemporary art world: private collectors and artist-entrepreneurs in the changing geographies of European art\u2019"], "Total_Cost": ["EUR 146 591,10"], "Country": ["United Kingdom"], "Project_ACR": ["Art market"], "Technology_Description": "This project examines the idea that there is an on-going re-privatization of the European art world, in which increasingly it is private art collectors and communities of artist-entrepreneurs that are creating commercial value in the contemporary art market and redrawing our cultural landscape. The rapid expansion of the global art market has meant that art has entered a period of radical institutional, market and industry transformation. Private art collectors and artist-entrepreneurs are now competing with public institutions and the locus of power is moving from public to private actors. This change calls for new critical investigations of agency, value creation and creativity of the art world. My work addresses an area of activity that is central to both European cultural and economic development. The thriving European art scene is a key field within the creative and cultural industries identified as central to Europe\u2019s development and integration by both the Creative Europe strategy and the Europe 2020 strategy. ", "To": ["2018-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["660629"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["MEDICAL RESEARCH COUNCIL"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Molecular basis for securin and cyclin ubiquitylation by the anaphase-promoting complex (APC/C)"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["APCINTERACTIONS"], "Technology_Description": "This research proposal describes an ambitious effort to characterize structurally and biochemically ubiquitin chain initiation and elongation by the anaphase-promoting complex or cyclosome (APC/C) in complex with two well-characterized substrates. The APC/C is a multi-subunit cullin-RING E3 ubiquitin ligase that controls progression through the cell cycle by a temporal regulation of its activity and substrate specificity. Regulation and specificity of this E3 ligase is achieved through mutually exclusive binding of two structurally related co-activator subunits termed Cdc20 and Cdh1, as well as through APC/C inhibitors, varying substrate affinities and auto-ubiquitylation of its cognate E2s, namely UbcH10 and Ube2S. In order to understand ubiquitin chain initiation and elongation of the two well-known APC/C substrates cyclin B and securin, I am aiming to use a combined approach of cryo-electron microscopy, X-ray crystallography and a variety of biochemical methods. Within this project I will use cryo-electron microscopy studies to uncover the molecular mechanisms of substrate recognition and ubiquitin chain initiation and elongation by analyzing the APC/CCdh1 co-activator complex bound to its transiently associated E2 enzymes Ube2S or UbcH10 and one of the aforementioned high affinity substrates. ", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations"], "From": ["2016-03-01"], "Project_ID": ["657725"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSIDAD CARLOS III DE MADRID", "UNIVERSIDAD CARLOS III DE MADRID"], "EU_Contribution": ["EUR 1 516 287,50"], "Project_Title": ["Market Design: Theory and Applications in Development"], "Total_Cost": ["EUR 1 516 287,50"], "Country": ["Spain", "Spain"], "Project_ACR": ["Market Design"], "Technology_Description": "There are two components to my research plan.", "To": ["2021-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-08-01"], "Project_ID": ["681575"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM", "JANSSEN CILAG SA", "VYSOKA SKOLA BANSKA - TECHNICKA UNIVERZITA OSTRAVA", "ASTRAZENECA AB", "UNIVERSITAT LINZ", "AALTO-KORKEAKOULUSAATIO", "INTEL CORPORATION", "IDEACONSULT LIMITED LIABILITY COMPANY", "ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE"], "EU_Contribution": ["EUR 3 910 140"], "Project_Title": ["Exascale Compound Activity Prediction Engine"], "Total_Cost": ["EUR 3 910 140"], "Country": ["Belgium", "Spain", "Czech Republic", "Sweden", "Austria", "Finland", "Belgium", "Bulgaria", "United Kingdom"], "Project_ACR": ["ExCAPE"], "Technology_Description": "Scalable machine learning of complex models on extreme data will be an important industrial application of exascale computers. In this project, we take the example of predicting compound bioactivity for the pharmaceutical industry, an important sector for Europe for employment, income, and solving the problems of an ageing society. Small scale approaches to machine learning have already been trialed and show great promise to reduce empirical testing costs by acting as a virtual screen to filter out tests unlikely to work. However, it is not yet possible to use all available data to make the best possible models, as algorithms (and their implementations) capable of learning the best models do not scale to such sizes and heterogeneity of input data. There are also further challenges including imbalanced data, confidence estimation, data standards model quality and feature diversity.", "To": ["2018-08-31, ongoing project |"], "Meta": [""], "Topic_s": ["FETHPC-1-2014 - HPC Core Technologies, Programming Environments and Algorithms for Extreme Parallelism and Extreme Data Applications"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Belgium"], "Activity": ["Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["671555"], "Call_for_Proposal": ["H2020-FETHPC-2014"]}, -{"Partners": ["ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Moment inequalities in matrix algebras"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["Moments"], "Technology_Description": "In the last few years the non-commutative moment inequalities have received a considerable attention in matrix analysis and operator theory. This phenomenon originates on the one hand in studies on the extreme properties of the standard deviation in quantum information theory, and on the other hand, in the recent concept and developments of quantum metric spaces. This research project will investigate trace inequalities in matrix algebras. Particular attention will be paid on moment inequalities for matrices with a special emphasis on their counterparts in operator algebras. It will focus on determining the best upper and lower bounds for higher order central moments in matrix algebras. This will be followed by a study of the relatively new concept of Leibniz seminorms in Banach algebras. The project will pursue a research on the strong Leibniz property of central moments in non-commutative probability spaces as well as in the classical ones in order to solve the recent question whether every centered moment has the strong Leibniz property or not.", "To": ["2017-08-31, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["653943"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSIDAD CARLOS III DE MADRID", "UNIVERSITE DE LORRAINE", "TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY", "CIMULEC", "AEROSERTEC SL"], "EU_Contribution": ["EUR 2 052 846,72"], "Project_Title": ["The outstanding challenge in solid mechanics: engineering structures subjected to extreme loading conditions"], "Total_Cost": ["EUR 2 052 846,72"], "Country": ["Spain", "France", "Israel", "France", "Spain"], "Project_ACR": ["OUTCOME"], "Technology_Description": "In this project we aim to train early-stage researchers in what is referred to as an outstanding challenge in solid mechanics: developing novel solutions for the analysis and design of aerospace and defense structures subjected to extreme loading conditions. Structural elements used in these sectors are frequently subjected to a large variety of unusually severe thermo-mechanical solicitations. One easily realizes that this type of structures (e.g. components for satellites) has to be designed to sustain extreme temperatures, which may vary hundred degrees in short periods of time, and extreme mechanical loadings like hypervelocity impacts. New specific structural solutions are constantly developed to fulfill such requirements, which place these industrial sectors in the forefront of the technological innovation. Hereby, aerospace and defense industries constitute the natural meeting point between academia and entrepreneurial fabric. A deep understanding of the response of structures under the aforementioned sharp solicitations is mandatory for design purposes. Unfortunately, not even today is easy to find researchers in the labour market with such specific (and complicated) understanding. Aerospace and defence industries require highly-qualified technical staff capable of developing research and innovation within the framework of structural mechanics. This is the precise context where our proposal lies. We intend to form a consortium composed of 3 academic beneficiaries and 2 industrial beneficiaries which aims at developing specific training for early-stage researchers within the field of aerospace and defense structures subjected to severe thermo-mechanical loads. The leitmotif of this ITN is to train creative and innovative researchers ready to face structural-engineering challenges which arise in the vanguard of technological innovation.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-01-01"], "Project_ID": ["675602"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["UNIVERSIDAD POLITECNICA DE MADRID", "UNIVERSIDAD POLITECNICA DE MADRID", "UNIVERSIDAD CARLOS III DE MADRID"], "EU_Contribution": ["EUR 2 497 000"], "Project_Title": ["Coherent Structures in Wall-bounded Turbulence"], "Total_Cost": ["EUR 2 497 000"], "Country": ["Spain", "Spain", "Spain"], "Project_ACR": ["COTURB"], "Technology_Description": "Turbulence is a multiscale phenomenon for which control efforts have often failed because the dimension of the attractor is large. However, kinetic energy and drag are controlled by relatively few slowly evolving large structures that sit on top of a multiscale cascade of smaller eddies. They are essentially single-scale phenomena whose evolution can be described using less information than for the full flow. In evolutionary terms they are punctuated \u2018equilibria\u2019 for which chaotic evolution is only intermittent. The rest of the time they can be considered coherent and predictable for relatively long periods. Coherent structures studied in the 1970s in free-shear flows (e.g. jets) eventually led to increased understanding and to industrial applications. In wall-bounded cases (e.g. boundary layers), proposed structures range from exact permanent waves and orbits to qualitative observations such as hairpins or ejections. Although most of them have been described at low Reynolds numbers, there are reasons to believe that they persist at higher ones in the \u2018LES\u2019 sense in which small scales are treated statistically. Recent computational and experimental advances provide enough temporally and spatially resolved data to quantify the relevance of such models to fully developed flows. We propose to use mostly existing numerical data bases to test the various models of wall-bounded coherent structures, to quantify how often and how closely the flow approaches them, and to develop moderate-time predictions. Existing solutions will be extended to the LES equations, methods will be sought to identify them in fully turbulent flows, and reduced-order models will be developed and tested. In practical situations, the idea is to be able to detect large eddies and to predict them \u2018most of the time\u2019. If simple enough models are found, the process will be implemented in the laboratory and used to suggest control strategies.", "To": ["2021-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-02-01"], "Project_ID": ["669505"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["INSTITUT NATIONAL D'ETUDES DEMOGRAPHIQUES", "UNIVERSITE CATHOLIQUE DE LOUVAIN", "UNIVERSITE DE GENEVE", "INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT", "UNIVERSITE PARIS OUEST NANTERRE LA DEFENSE"], "EU_Contribution": ["EUR 868 500"], "Project_Title": ["Emerging population issues in sub-Saharan Africa: Cross-checking and promoting demographic data for better action"], "Total_Cost": ["EUR 868 500"], "Country": ["France", "Belgium", "Switzerland", "France", "France"], "Project_ACR": ["DEMOSTAF"], "Technology_Description": "DEMOSTAF (DEMOgraphy-STatistics-for-Africa) brings together European and African research institutes as well as non academic African national statistics offices (NSOs) in a staff exchange programme, for a period of 48 months, with the aim to advance research on emerging population issues in Sub-Saharan Africa (SSA). DemoStAf is built around four major population-related themes: fertility, mortality & health, households & families and education. These themes federate the research projects conducted by the partners, and aim to shed light on key contemporaneous questions, with the objective to inform the post-2015 development agenda framed in the Sustainable Development Goals (SDGs) currently in discussion. The programme focuses on the articulation between quantitative data from national statistics (censuses and sample surveys) and local data (demographic surveillance systems or local vital registration). Thanks to the close involvement of NSOs, the programme will consolidate and promote public statistics. The programme will finance staff mobility between partners for supporting research projects, while reinforcing training and skill transfers. Collective activities essentially devoted to training, data documentation and scientific dissemination are also planned. DemoStAf involves 17 partners: 4 European academic institutions, well known for their African population expertise (INED and IRD in France, UCL in Belgium, Unige in Switzerland), 12 African partners from Burkina Faso (INSD and ISSP), Kenya (APHRC), Madagascar (INSTAT, INSPC, IPM, UCM), Mali (INSTAT), Senegal (ANSD, UCAD, UZ) and Uganda (UM). Among them, 4 are NSOs. Due to mutual interests in the promotion of demographic data, a Canadian academic institution (ODSEF) is also involved. A scientific advisory committee with 11 members associates key experts and promote international partnerships. In total, 94 individuals participate, 74 are involved in 166 secondments (that correspond to 193 months).", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["690984"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["UNIVERSIDAD CARLOS III DE MADRID", "UNIVERSIDAD CARLOS III DE MADRID"], "EU_Contribution": ["EUR 1 133 396"], "Project_Title": ["The Transformation of Popular Politics in Europe\u2019s Long Nineteenth Century"], "Total_Cost": ["EUR 1 133 396"], "Country": ["Spain", "Spain"], "Project_ACR": ["TRANSPOP"], "Technology_Description": "How did ordinary people acquire the capacity to mobilize and influence the political decision-making process? How did standard forms of popular collective action emerge and get institutionalized in European modernity? To address these questions, this project explores the transformation of European popular politics in the long nineteenth-century (c. 1789-1914), while also offering a systematic and empirically rigorous causal account of the processes that led to the emergence of the typical forms of social movement activities that dominate the current landscape of popular protest. ", "To": ["2020-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-08-01"], "Project_ID": ["648429"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN", "RUHR-UNIVERSITAET BOCHUM", "RIJKSUNIVERSITEIT GRONINGEN", "UNIVERSIDAD DE LA IGLESIA DE DEUSTO ENTIDAD RELIGIOSA", "FUTURE ANALYTICS CONSULTING LIMITED", "CONCERN WORLDWIDE LBG", "PLAN LIMITED"], "EU_Contribution": ["EUR 1 129 500"], "Project_Title": ["Preparedness and Resilience to address Urban Vulnerability"], "Total_Cost": ["EUR 1 129 500"], "Country": ["Ireland", "Germany", "Netherlands", "Spain", "Ireland", "Ireland", "United Kingdom"], "Project_ACR": ["PRUV"], "Technology_Description": "The challenge posed by urban vulnerability is immense and is being compounded by rapid unplanned urbanisation, climate change and resource pressures. While the realisation that there is a fundamental shift in the landscape of crises to cities is no longer contested, aid actors are nonetheless grappling with the complexities of adapting their approaches to the urban context. The Preparedness and Resilience to address Urban Vulnerability (PRUV) Consortium aims to inform the pressing need to reshape how humanitarian action and development aid is undertaken in urban areas to address the challenge posed by urban vulnerability. ", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-01-01"], "Project_ID": ["691060"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF EV", "ABENGOA RESEARCH SL", "CRANFIELD UNIVERSITY", "METAL ESTALKI SL", "NANO4ENERGY SLNE", "PROFACTOR GMBH"], "EU_Contribution": ["EUR 346 500"], "Project_Title": ["Framework of Innovation for Engineering of New Durable Solar Surfaces"], "Total_Cost": ["EUR 346 500"], "Country": ["Germany", "Spain", "United Kingdom", "Spain", "Spain", "Austria"], "Project_ACR": ["FRIENDS2"], "Technology_Description": "Increasing the share of renewables in the European energy mix has a key function for the security of energy supply and the reduction of greenhouse gas emissions from fossil fuels. This proposal is entitled \u201cFramework of Innovation for Engineering of New Durable Solar Surfaces\u201d, (acronym FRIENDS2) and aims at achieving a European network for the transfer of knowledge to establish a shared culture of research and innovation which allows turning creative ideas in the field of surface engineering into innovative solutions for concentrating solar power (CSP) applications. FRIENDS2 will be led by one large European industry (Abengoa) who is a world leader in the development of CSP plants. The other FRIENDS2 participants are two well-recognized academic organizations (the University of Cranfield and the Helmholtz-Zentrum Dresden - Rossendorf e.V.), and one SME (Metal Estalki). The purpose of FRIENDS2 is to strengthen the inter-sectoral capabilities in research and development of coating designs in order to improve the performance of CSP key components (reflectors, receivers and containers for heat storage) for high temperature applications. The methodology of this joint research proposal contains aspects of very high novelty. It includes computer modelling, multi-technique coating deposition, use of advanced characterization techniques, and the possibility of scaling-up new coating developments. Special attention is paid to the intersectoral transfer of knowledge and to the establishment of a long-lasting international network with global impact. It is worth noting that a substantial fraction of secondments (51%) will be carried out from the industrial to the academic sector. With the proposed approach, there will be an effective transfer of knowledge among the partners which will pave the road from fundamental research to applied innovation of surface engineering solutions for further CSP development.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Christian Eitzinger", "Tel.: +43 7282 885250", "Fax: +43 7252 885101"], "From": ["2015-01-01"], "Project_ID": ["645725"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["THE UNIVERSITY OF WARWICK", "THE UNIVERSITY OF BIRMINGHAM", "KARLSRUHER INSTITUT FUER TECHNOLOGIE", "CARL VON OSSIETZKY UNIVERSITAET OLDENBURG", "TTY-SAATIO", "ASOCIACION CENTRO TECNOLOGICO CEIT-IK4"], "EU_Contribution": ["EUR 841 500"], "Project_Title": ["Design and Fabrication of Functional Surfaces with Controllable Wettability, Adhesion and Reflectivity"], "Total_Cost": ["EUR 1 291 500"], "Country": ["United Kingdom", "United Kingdom", "Germany", "Germany", "Finland", "Spain"], "Project_ACR": ["FabSurfWAR"], "Technology_Description": "The project \u201cDesign and Fabrication of Functional Surfaces with Controllable Wettability, Adhesion and Reflectivity (FabSurfWAR)\u201d focuses on the staff exchange between the partners of EU and Asia, and the development of key enabling techniques of designing and generating micro/nano surface topology with better control of bacterial growth, adhesion, friction and other tribological properties for potential applications from surgical tools, biomedical devices, to turbine blades and agricultural machines. It meets the objectives and requirements of the Marie Sk\u0142odowska-Curie Actions: Research and Innovation Staff Exchange (RISE), by establishing multiple bridges between European and Asian institutions.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2015-01-01"], "Project_ID": ["644971"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["AARHUS UNIVERSITET"], "EU_Contribution": ["EUR 4 956 000"], "Project_Title": ["AIAS-COFUND II Fellowship Programme"], "Total_Cost": ["EUR 9 912 000"], "Country": ["Denmark"], "Project_ACR": ["AIAS-COFUND II"], "Technology_Description": "The overall aim of the AIAS-COFUND II Fellowship Programme is to reinforce excellent research by establishing a large scale fellowship programme offering long term fellowships (lasting 6-36 months) in which researchers gain freedom and independence to develop their own ideas with access to excellent facilities. The AIAS-COFUND II Fellowship Programme will enhance fellows\u2019 genuine understanding of the methodologies and approaches of other scientific disciplines at the highest level, and thus make cross-disciplinary inspiration and initiatives possible. The aim is also to establish a multidisciplinary training platform to strengthen researchers\u2019 capabilities to work anywhere in Europe and attract researchers from around the globe to Europe and thereby contributing to the European goals of increasing the numbers of researchers with innovation skills in Europe by 2020.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2016 - Co-funding of regional, national and international programmes"], "Funding_scheme": ["MSCA-COFUND-FP - Fellowship programmes"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["754513"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2016"]}, -{"Partners": ["TECHNISCHE UNIVERSITAET MUENCHEN"], "EU_Contribution": ["EUR 5 664 000"], "Project_Title": ["International Network of Excellence in Science Technology"], "Total_Cost": ["EUR 11 328 000"], "Country": ["Germany"], "Project_ACR": ["EuroTechPostdoc"], "Technology_Description": "Combining complementary research & innovation strengths with unique infrastructures across four leading European Universities of Science & Technology will provide the basis for an internationally competitive fellowship programme. The new EuroTechPostdoc programme aims at attracting excellent experienced researchers from all over the world through an open, transparent and structured recruitment process. EuroTechPostdoc will provide exceptional research and training opportunities for up to 80 experienced researchers funded for a 2-year period (divided in 2 calls, 10 fellowships per participant per call). The fellows will develop their skills in interdisciplinary collaboration projects between at least two participants from two different European countries, and will be provided with the opportunity to transfer knowledge in entrepreneurship activities or by collaboration with public and industrial organisations from the combined networks of the participants. The research programme has been carefully selected to provide the fellows with the complementary strengths, established networks and industrial collaboration in areas of high relevance to the EU\u2019s industrial leadership: Health & Bioengineering, Smart & Urban Mobility, Data Science & Engineering, High Performance Computing, Entrepreneurship & Innovation. The fellows will gain access to the excellent and complementary training options offered at the four participants, and will be supported by a personal supervision and mentoring scheme, as well as excellent local support structures. The EuroTechPostdoc 3-days Workshop focuses on strengthening the fellows\u2019 skills and network, preparation ahead of their careers and to foster further collaborative projects between the fellows. Together with outstanding working conditions that support both family and career, the programme will thus provide the fellows with unprecedented possibilities to diversify their career options for a leadership position within the ERA.", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2016 - Co-funding of regional, national and international programmes"], "Funding_scheme": ["MSCA-COFUND-FP - Fellowship programmes"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["754462"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2016"]}, -{"Partners": ["TEAGASC - AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY"], "EU_Contribution": ["EUR 2 124 000"], "Project_Title": ["Research Leaders 2025 - A Fellowship Programme developing the Next Generation of Agri-Food Research Leaders"], "Total_Cost": ["EUR 4 248 000"], "Country": ["Ireland"], "Project_ACR": ["ResearchLeaders2025"], "Technology_Description": "The overriding objective of this programme is to foster the next generation of agri-food research leaders. Inspired by the Marie Sk\u0142odowska-Curie Actions (MSCA) Global Fellowships, it focuses on researcher-driven mobility. The programme offers applicants the opportunity to conduct their research in an academic or non-academic organisation of their choice worldwide (outside of Ireland) for 18 months, followed by a return phase to Teagasc (Ireland) for 18 months. The applicant will freely choose the research topic, the outgoing host (and supervisor) and the supervisor for the return phase. In addition, if the outgoing phase is with an academic host, they may choose to incorporate a secondment for up to six months to a non-academic collaborator of their choice. Interdisciplinary projects will be encouraged and facilitated. The programme will have a total value of \u20ac5.2 million (\u20ac2.1 million from EC). It will run for 60 months and will have two funding calls; each funding 10 fellowships (total 20 fellowships). Each fellowship will last 36 months. There will be a strong focus on the career development of the researchers, with all fellows undertaking an accredited management course, having a dedicated career mentor (separate to their scientific supervisors) and attending an annual retreat with presentations from established research leaders in industry, academia and civil society organisations. The need to address the \u201cleaky pipeline\u201d whereby many promising female researchers do not achieve senior positions is a strong focus of the programme. An International Expert Advisory Board will review all documentation for the programme to ensure that there is no unintended bias against, or discouragement of, female applicants. Remote review cohorts and the final review panel will be gender balanced. A dedicated section of the website will highlight positive reasons for female researchers to apply for the fellowship.", "To": ["2023-07-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2016 - Co-funding of regional, national and international programmes"], "Funding_scheme": ["MSCA-COFUND-FP - Fellowship programmes"], "Coordinated_in": ["Ireland"], "Activity": ["Research Organisations"], "From": ["2018-08-01"], "Project_ID": ["754380"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2016"]}, -{"Partners": ["UNIVERSITY OF KENT", "UNIVERSIDAD CARLOS III DE MADRID", "UNIVERSITA DEGLI STUDI ROMA TRE", "POLITECHNIKA WARSZAWSKA", "OTTO-VON-GUERICKE-UNIVERSITAET MAGDEBURG"], "EU_Contribution": ["EUR 2 505 152,16"], "Project_Title": ["AMBER - enhAnced Mobile BiomEtRics"], "Total_Cost": ["EUR 2 505 152,16"], "Country": ["United Kingdom", "Spain", "Italy", "Poland", "Germany"], "Project_ACR": ["AMBER"], "Technology_Description": "Over recent years the ubiquity of mobile platforms such as smartphones and tablets devices has rapidly increased. These devices provide a range of untethered interaction unimaginable a decade previously. With this ability to interact with services and individuals comes the need to accurately authenticate the identity of the person requesting the transaction many of which carry financial/legally-binding instruction. Biometric solutions have also seen increased prominence over the past decade with large-scale implementations in areas such as passport and national ID systems. The adoption of specific biometric sensors by mobile vendors indicates a long-term strategy as a means of authentication. This adoption is is at critical point \u2013 users need to be confident of biometrics in terms of usability, privacy and performance; compromise in any one of these categories will lead to mistrust and a reluctance to adopt over and above conventional forms of authentication. The design, implementation and assessment of biometrics on mobile devices therefore requires a range of solutions to aid initial and continued adoption. The EU needs to have experts trained specifically in the field to ensure that it participates, competes and succeeds in the global market. ", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["675087"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI UDINE"], "EU_Contribution": ["EUR 180 277,20"], "Project_Title": ["Volcano-seismic Unsupervised Labelling and ClAssificatioN Embedded in A Real-time Scenario"], "Total_Cost": ["EUR 180 277,20"], "Country": ["Italy"], "Project_ACR": ["VULCAN.ears"], "Technology_Description": "Volcanic activity has a big impact on the economy and society. Nowadays, volcano monitoring (VM) is mainly based on the analysis of the seismicity, specifically on some type of precursory events (or classes) which appear before an eruption. The variability of the volcano-seismic classes and the increase of the seismicity in a volcano crisis difficult the manual supervised classification carried out by expert technicians to detect an event and assign it to its proper class. Most of the VM observatories demand an automatic Volcano Seismic Recognition (VSR) to quickly detect and analyse the precursory seismicity and to correctly assess the population risk, avoiding human casualties. Nevertheless, only a few VM facilities have their own VSR prototypes designed to monitor their volcanoes.", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["749249"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["INTERDISCIPLINARY CENTER (IDC) HERZLIYA"], "EU_Contribution": ["EUR 263 385"], "Project_Title": ["Estimating a DSGE Model with Rare Disasters"], "Total_Cost": ["EUR 263 385"], "Country": ["Israel"], "Project_ACR": ["DSGE-RD"], "Technology_Description": "\"This project will estimate a DSGE model with rare disasters using data from the Great Recession. Previous studies on rare disasters have been confined mainly to endowment economies. Extensions to production economies (business cycle models) have been limited. In particular, DSGE models with rare disasters have not been estimated before. The main obstacle is computational, as these models are very difficult to solve. ", "To": ["2020-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["746653"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ACIES BIO BIOTEHNOLOSKE RAZISKAVE IN RAZVOJ DOO"], "EU_Contribution": ["EUR 157 287,60"], "Project_Title": ["Metabolic Drivers of Epigenetic Modifications: metabolic inducers of histone post-translational modifications in a biological setting"], "Total_Cost": ["EUR 157 287,60"], "Country": ["Slovenia"], "Project_ACR": ["M-DrivE"], "Technology_Description": "Post-translational chemical modifications to histone proteins \u2013 the storage units of DNA \u2013 influence gene expression electrostatically and through specific protein-protein interactions, the study of which is known as epigenetics. Although many enzymes have been identified which add, remove or recognise these modifications, the implication of metabolism in the induction of epigenetic states is a recent development \u2013 particularly highlighting acetyl coenzyme A (CoA) as the sole donor for acetylation. Due to the lack of appropriate biochemical tools, this emerging field has not yet been exploited, however Acies Bio\u2019s leading work on the efficient synthesis of 4\u2019 phosphopantetheine (4-PPT), a natural precursor of the prolific substrate CoA, places us in a unique position to realise the novel approach of metabolically inducing epigenetic modifications. In progress towards therapeutic use bypassing faulty metabolism in a rare genetic disorder, we have shown that 4-PPT is cell permeable, serum-stable, tolerated at high doses without side-effects, and can also upregulate histone acetylation. This presents a previously unexplored route to develop 4-PPT as a novel vehicle for the delivery of diverse intracellular acyl-CoA species, and subsequent histone modification. Taking advantage of the interplay between metabolic and epigenetic states, and the complementarity of backgrounds that Acies Bio and Dr Sekirnik can provide through an international partnership combining expertise in both fields, our proposed work would illuminate recently characterised histone acylations. By synthesising novel 4-PPT derivatives, and demonstrating their activity on a cellular and model organism level, we will develop new tools to enable rapid enrichment of rare endogenous modifications to probe their function. This would form the first demonstration of use of native enzyme substrates to affect epigenetic states, affording new European research opportunities in both metabolomics and epigenetics.", "To": ["2020-04-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-SE - Society and Enterprise panel"], "Coordinated_in": ["Slovenia"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-05-01"], "Project_ID": ["748139"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["Institute of Science and Technology Austria"], "EU_Contribution": ["EUR 4 590 200"], "Project_Title": ["ISTplus - Postdoctoral Fellowships"], "Total_Cost": ["EUR 9 180 400"], "Country": ["Austria"], "Project_ACR": ["ISTplus"], "Technology_Description": "ISTplus offers two-year fellowships for highly qualified, incoming postdocs fulfilling the mobility criterion, who will have the chance to join our world-class research teams in the fields of Biology, Neuroscience, Mathematics, Physics, and Computer science at IST Austria. The fellows will be integrated in a truly interdisciplinary research environment, interacting closely with colleagues from different fields (through shared facilities, joint projects, and events). The international dimension will be ensured by the multinational teams (with employees from more than 50 countries) and through international networking. ", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2016 - Co-funding of regional, national and international programmes"], "Funding_scheme": ["MSCA-COFUND-FP - Fellowship programmes"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["754411"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2016"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Proton CT reconstruction with a Cone Beam CT prior"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["protonCBCT"], "Technology_Description": "\"Proton therapy has become a superioralternative to conventional radiotherapy for certain clinical indications. It potentially allows to deliver high dose to the tumor while sparing healthy surrounding tissue. However, a reduction of treatment uncertainties is required to fully exploit this advantage and precise knowledge of the relative stopping power (RSP) of the patient tissues on the day of treatment is needed to correctly predict the proton range in the treatment planning system (TPS). Modern imaging technology plays a key role here. ", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2017-06-01"], "Project_ID": ["753370"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Computational design of proteins binding nucleosomal DNA with specificity for therapeutic applications"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["DesProtDNA"], "Technology_Description": "DNA compresses in the cell by forming nucleosome particles, which diminish the accessibility of transcription factors to DNA and provide fine regulatory mechanisms for gene expression and replication. Some proteins can still bind the exposed face of nucleosomal DNA and are known to promote cancer or viral infection, and strategies to block such binding events are promising for developing new epigenetic-like therapies. However, structural information on proteins binding nucleosomal DNA is too limited for the rational design of new drugs. The current proposal aims to combine expertise of the researcher (on protein design) and the host group (on DNA and protein-DNA interactions) to computationally design and experimentally test proteins binding nucleosomal DNA with specificity. The researcher will first develop a computational design protocol and subsequently test it against nucleosomes of known structure. After experimental validation, he will design proteins blocking the nucleosomal DNA sites targeted by two proteins (FoxA1 and GATA) known to promote breast and prostate cancer. The proposed project uses computational approaches for designing protein structures and protein-DNA interactions, and experimental approaches to characterize protein-DNA binding and structure of the designed complexes. This multidisciplinary project is devised to expand the design capabilities of the researcher towards protein-DNA interactions, which hold great potential for medical and biotechnological applications, in a research context of high biomedical impact. This project devises a training plan on computational, experimental and transferable skills necessary for an independent research position, and provides an opportunity to bring protein design approaches into the European research. The novelty of this protein-DNA design approach will be of wide interest for the scientific and non-scientific communities, and will be disseminated accordingly.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-04-01"], "Project_ID": ["749059"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["A calcifying phytoplankter\u2019s response to climate change and its role in sinking carbon in the Subarctic Ocean using spaceborne and in situ observations and ecological modelling"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["WhiteShift"], "Technology_Description": "Anthropogenic carbon dioxide emissions are skyrocketing, resulting in ocean warming and acidification. Yet we are only beginning to understand how this human footprint impacts phytoplankton and associated sinking carbon fluxes to the deep ocean. WhiteShift addresses these questions for a marine calcifying phytoplankter in one of the most climate sensitive regions, the Subarctic Ocean, where the species is expanding its range northward. First, we investigate the impact of a changing ocean on the spatiotemporal distribution of the species by a novel integrative approach connecting long-term optical satellite observations with fundamental ecological theory. Next, we examine if the enormous amounts of calcite produced by this species ballast organic carbon using optical technology on autonomous profiling floats. WhiteShift\u2019s generic methodology and integrative framework is directly transportable to the global ocean and will provide important new insights into the ocean-climate nexus.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["749949"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Collectiveware: Highly-parallel algorithms for collective intelligence"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["HPA4CF"], "Technology_Description": "In recent years, more and more scenarios pose challenges that require collective intelligence solutions based on networks (knowledge networks, social networks, sensor networks). New forms of collaborative consumption, collaborative making, collaborative production, all rely on a common task, the formation of collectives. This task is crucial in many real-world applications domains. Notable examples of actual-world collective formation scenarios are Collective Energy Purchasing (CEP), a collaborative consumption scenario, and Team Formation (TF), a collaborative production scenario. Within the Artificial Intelligence literature, current state of the art algorithms cannot provide the level of scalability and the solution quality required by actual-world collective formation problems, hence novel algorithms are needed to tackle these problems. To achieve this objective, we aim at proposing novel algorithms that are capable to exploit modern highly-parallel architectures. On the one hand, highly-parallel architectures have been successfully applied in many different scenarios so to achieve tremendous performance improvements. These advancements encourage the investigation of parallelisation also in collective formation, with the objective of achieving the same benefits. On the other hand, our past research indicates that considering the structure of the collective formation problem leads to notable benefits in terms of scalability and solution quality. Thus, we propose to take a novel algorithmic design approach that considers both the structure of the scenario and at the same time exploits modern highly-parallel architectures. Our algorithms will be evaluated in two prominent collective intelligence application domains: the CEP and TF domains. The choice of these two application domains will serve to show the generality of our algorithmic design approach, since they are representative of two structurally different families of actual-world collective formation problems.", "To": ["2019-06-15, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-06-16"], "Project_ID": ["751608"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE DE GENEVE"], "EU_Contribution": ["EUR 175 419,60"], "Project_Title": ["Intrinsically chiral gold nanoclusters as enantiodiscriminating sensors for methamphetamines."], "Total_Cost": ["EUR 175 419,60"], "Country": ["Switzerland"], "Project_ACR": ["GOLDENSENS"], "Technology_Description": "\"The GOLDENSENS project aims at creating a new class of enantiodiscriminating sensors for methamphetamines based on intrinsically chiral Au38(SR)24 nanoclusters. These materials have unique optical properties which make them capable of conferring chirality to thiols protecting their surface, even when ligands themselves are achiral. The result of this chirality transfer is the formation of an asymmetric environment on the cluster surface which will be used for the enantiodiscrimination of D- and L-methamphetamines which can have distinct biological effects (The D-enantiomer is diffuse as psychotropic drug, whereas the L-enantiomer have been applied in medicine as in nasal decongestant). The first objective of GOLDENSENS will be the preparation of functional Au38 clusters. The protecting thiols of these novel clusters will bear specific chemical groups able to increase the enantioselective interactions with methamphetamines. The second objective will be the investigation of chiral properties of these gold nanoclusters by a combined chiroptical techniques and theoretical calculations. Ultimately, GOLDENSENS will investigate the enantiodiscriminating activity of prepared Au38 clusters towards methamphetamines, leading to the development of novel methods for enantiomeric separation. NMR-based techniques will quantify enantioselective interactions and \"absolute configuration modulation infrared spectroscopy\" will clarify the mechanism of enantiodiscrimination by gold nanoclusters. Results and knowledge generated with GOLDENSENS will impact the understanding of chirality at the nanoscale, contributing to the growth of an emerging and frontier research field. The training provided by the project will help the experienced researcher to refine scientific and soft skills, ultimately acquiring all the abilities and competences necessary to start an independent academic career in nanotechnology.\"", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["747209"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 301 863"], "Project_Title": ["GeoLocLang"], "Total_Cost": ["EUR 1 301 863"], "Country": ["France", "France"], "Project_ACR": ["GeoLocLang"], "Technology_Description": "\"I formulated recently a conjecture that should allow to geometrize the local Langlands correspondence over a non-archimedean local field. This mixes p-adic Hodge theory, the geometric Langlands program and the classical local Langlands correspondence. This conjecture says that given a discrete local Langlands parameter of a reductive group over a local field of equal or unequal characteristic, one should be able to construct a perverse Hecke eigensheaf on the stack of G-bundles on the \"curve\" I defined and studied in my joint work with Fontaine. ", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-10-01"], "Project_ID": ["742608"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITAT POLITECNICA DE VALENCIA", "UNIVERSITAT POLITECNICA DE VALENCIA"], "EU_Contribution": ["EUR 2 494 444"], "Project_Title": ["Universal microwave photonics programmable processor for seamlessly interfacing wireless and optical ICT systems"], "Total_Cost": ["EUR 2 494 444"], "Country": ["Spain", "Spain"], "Project_ACR": ["UMWP-CHIP"], "Technology_Description": "Information and communication technology (ICT) systems are expanding at an awesome pace in terms of capacity demand, number of connected end-users and required infrastructure. To cope with these rapidly increasing growth rates there is a need for a flexible, scalable and future-proof solution for seamlessly interfacing the wireless and photonic segments of communication networks. ", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["741415"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSIDAD POMPEU FABRA"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["A Theory of Reference for Distributional Semantics"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["ThReDS"], "Technology_Description": "One of the most fundamental human faculties is 'reference': the capacity to 'talk about things'. This extraordinary ability is at the core of many forms of human exchange, from asking for the salt at the dinner table to collaboratively building a solar probe. It involves using linguistic signs to identify things in the world and bring them to the mind of another. Reference is poorly understood: in particular, we do not know how humans build a shared linguistic representation of their environment, which they use to link words and world. My goal is to build a computational model of the way people acquire world knowledge from language and translate knowledge back into language. My overall framework includes three steps: 1) creating a representation of the way people 'talk about things', using distributional semantics (DS: a computational approach to modelling word usage); 2) automatically mapping the distributional model onto a partial set-theoretic model (a formal knowledge representation expressing shared beliefs about the world); 3) using the set-theoretic model to generate unobserved linguistic expressions which refer. The pipeline will be evaluated via an online game where a computer has to produce references to well-known concepts and individuals for a human tester. This work will significantly advance the state-of-the-art in linguistics: while DS has enjoyed considerable success in modelling lexical phenomena, it is currently showing its limits in explaining referential aspects of meaning. Conversely, referential semantics is still far from fully explaining the cognitive aspects of concept acquisition and reuse. The proposed investigation requires a very novel integration of computational semantics (my area of expertise) and formal linguistics (in which my host is an internationally recognised expert). The collaboration will give us the chance to lead a burgeoning area of research aiming at integrating reference into DS.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["751250"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FORSCHUNGSVERBUND BERLIN EV", "UNI RESEARCH AS", "UNIVERSITETET I BERGEN", "KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW", "AREFSENS ELECTRONICS BIOTECHNOLOGY INC", "BLUE LOBSTER IT LIMITED", "HELLENIC CENTRE FOR MARINE RESEARCH", "MIDDLE EAST TECHNICAL UNIVERSITY", "HELMHOLTZ ZENTRUM FUR OZEANFORSCHUNG KIEL", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UMEA UNIVERSITET", "WasserCluster Lunz - Biologische Station GmbH", "LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN", "ECOLE NORMALE SUPERIEURE", "AARHUS UNIVERSITET", "SUOMEN YMPARISTOKESKUS", "HELSINGIN YLIOPISTO", "UNIVERSIDADE DE EVORA", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "NORSK INSTITUTT FOR VANNFORSKNING", "UMWELTBUNDESAMT"], "EU_Contribution": ["EUR 9 999 804,75"], "Project_Title": ["Network of Leading European AQUAtic MesoCOSM Facilities Connecting Mountains to Oceans from the Arctic to the Mediterranean"], "Total_Cost": ["EUR 9 999 806,57"], "Country": ["Germany", "Norway", "Norway", "Netherlands", "Turkey", "United Kingdom", "Greece", "Turkey", "Germany", "France", "Sweden", "Austria", "Germany", "France", "Denmark", "Finland", "Finland", "Portugal", "United Kingdom", "Norway", "Germany"], "Project_ACR": ["AQUACOSM"], "Technology_Description": "Experimentation in mesocosms is arguably the single most powerful approach to obtain a mechanistic quantitative understanding of ecosystem-level impacts of stressors in complex systems, especially when embedded in long-term observations, theoretical models and experiments conducted at other scales. AQUACOSM builds on an established European network of mesocosm research infrastructures (RI), the FP7 Infra project MESOAQUA (2009-2012), where 167 users successfully conducted 74 projects. AQUACOSM greatly enhances that network on pelagic marine systems in at least 3 ways: first by expanding it to 10 freshwater (rivers and lakes), 2 brackish and 2 benthic marine facilities, and by involving 2 SMEs and reaching out to more, thereby granting effective transnational access to world-leading mesocosm facilities to >340 users on >11500 days; second, by integrating scattered know-how between freshwater and marine RI; and third, by uniting aquatic mesocosm science in an open network beyond the core consortium, with industry involved in an ambitious innovation process, to promote ground-breaking developments in mesocosm technology, instrumentation and data processing. A new dimension of experimental ecosystem science will be reached by coordinated mesocosm experiments along transects from the Mediterranean to the Arctic and beyond salinity boundaries. These efforts will culminate in a joint research activity (JRA) to assess aquatic ecosystem responses across multiple environmental gradients to a selected climate-related key stressor with repercussions for ecosystem services. Overall, AQUACOSM will fill a global void by forging an integrated freshwater and marine research infrastructure network. Long-term sustainability is sought through assessing governance models based on science priorities and economic innovation opportunities. Linkages to and synergies with ESFRI RI and other large initiatives are ensured by AQUACOSM partners and Advisory Board members in those programs.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["INFRAIA-01-2016-2017 - Integrating Activities for Advanced Communities"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations"], "From": ["2017-01-01"], "Project_ID": ["731065"], "Call_for_Proposal": ["H2020-INFRAIA-2016-1"]}, -{"Partners": ["UNIVERSIDAD CARLOS III DE MADRID", "UNIVERSIDAD CARLOS III DE MADRID"], "EU_Contribution": ["EUR 1 424 000"], "Project_Title": ["Information Theory for Low-Latency Wireless Communications"], "Total_Cost": ["EUR 1 424 000"], "Country": ["Spain", "Spain"], "Project_ACR": ["LOLITA"], "Technology_Description": "The majority of wireless connections in the fifth generation (5G) of wireless systems will most likely be originated by autonomous machines and devices rather than by the human-operated mobile terminals for which traditional broadband services are intended. It is thus expected that enhanced mobile-broadband services will be complemented by new services centered on machine-type communications (MTC). An important emerging area among MTC systems is that of low-latency communications, which targets systems that require reliable real-time communication with stringent requirements on latency and reliability.", "To": ["2022-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-03-01"], "Project_ID": ["714161"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["UNIVERSITAT WIEN", "UNIVERSITAT WIEN"], "EU_Contribution": ["EUR 2 495 190,99"], "Project_Title": ["The Normative and Moral Foundations of Group Agency"], "Total_Cost": ["EUR 2 495 190,99"], "Country": ["Austria", "Austria"], "Project_ACR": ["Group Agency"], "Technology_Description": "Though philosophers have debated intensely the issue of group agency in the last years, little scholarly work has yet been done on the normative constitution of group agents. The present project will fill this lacuna in a groundbreaking way. A philosophical analysis of the constitutive conditions of individual and collective agency will be combined with recent research in moral philosophy, legal theory and economic theory on the organisational structure of institutional agency. The first aim of the project is to provide a detailed philosophical investigation of the normative foundations of group agency and to work out the rational and moral norms that constitute and guide group agents. The second aim is to explore the implications of such an analysis for moral and legal philosophy. The third aim of the project is to apply the philosophical results to a normative analysis of corporate and economic agents.", "To": ["2022-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["740922"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSIDAD CARLOS III DE MADRID", "UNIVERSIDAD CARLOS III DE MADRID"], "EU_Contribution": ["EUR 1 325 158"], "Project_Title": ["Frontiers in Phononics: Parity-Time Symmetric Phononic Metamaterials"], "Total_Cost": ["EUR 1 325 158"], "Country": ["Spain", "Spain"], "Project_ACR": ["PHONOMETA"], "Technology_Description": "The boost experienced by acoustic and elastic (phononic) metamaterial research during the past years has been driven by the ability to sculpture the flow of sound waves at will. Thanks to recent developments at the frontiers of phononic metamaterials it can be identified that active phononic control is at the cutting edge of the current research on phononic metamaterials. Introducing piezoelectric semiconductors as a material platform to discover new avenues in wave physics will have the potential to open horizons of opportunities in science of acoustic wave control. Electrically biased piezoelectric semiconductors are non-reciprocal by nature, produce mechanical gain and are highly tunable. ", "To": ["2021-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-12-01"], "Project_ID": ["714577"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["MYcenaean SOcial BIOarchaeology: Deciphering the interplay of funerary treatment and social dynamics in the Mycenaean period"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["MYSOBIO"], "Technology_Description": "MYSOBIO investigates the complex relationship between funerary treatment and wider social dynamics through a novel interpretive model based on the contextual analysis of human skeletal remains and associated mortuary data. The research focusses on the post-mortem treatment of the body in collective mortuary assemblages. The main aim is to reconstruct, to a new level of detail, development in Mycenaean mortuary practice in the Late Bronze Age Aegean (1700-1050 BC). MYSOBIO will unravel the diversity of social responses at death and their mutual relationship with wider socio-political developments, instrumental in the rise and fall of the Mycenaean palaces, one of the first complex societies in Europe. To achieve this, it employs, for the first time, a holistic bioarchaeological approach that integrates up-to-date theoretical reflection in mortuary archaeology with cutting-edge, interdisciplinary scientific advances in the study of collective skeletal assemblages. This methodology brings together traditional archaeology, current mortuary theory, biological anthropology, funerary taphonomy, forensic sciences and archaeo-thanatology, further enhanced by state-of-the-art technological innovations from other scientific fields (social geography, applied mathematics, geomatics and archaeogenetics). The Fellowship will offer to the Experienced Researcher (ER) the opportunity to receive advanced training in these fields and achieve the research objectives, creating a new methodological pathway to the social dimensions of prehistoric mortuary assemblages with world-wide implications for Social Bioarchaeology. At the same time, the ER will attain professional maturity and greatly advance her career perspectives. She will acquire significant transferable skills, establish lasting multidisciplinary research networks, motivate the youth and educate the public on the social significance of archaeological research and the benefits of science.", "To": ["2020-01-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-15"], "Project_ID": ["747458"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN"], "EU_Contribution": ["EUR 3 540 000"], "Project_Title": ["The LMU Research Fellowship Program: Promoting excellent early-stage postdoctoral researchers at LMU Munich"], "Total_Cost": ["EUR 7 080 000"], "Country": ["Germany"], "Project_ACR": ["LMUResearchFellows"], "Technology_Description": "As a leading European research university, Ludwig-Maximilians-Universitaet (LMU) Muenchen is committed to providing optimal conditions and reliable career paths for early-career researchers. To this end, the University aims to expand its successful LMU Research Fellowship Program, which provides excellent research options and professional training conditions for outstanding international postdoctoral researchers from any field of research. The program gives Research Fellows the opportunity to carry out their own independent research project with the support of an LMU professor. As part of COFUND, the program will be differentiated into an incoming and a new outgoing fellowship scheme and provide additional international and cross-sectoral training opportunities to foster the mobility of Research Fellows. Incoming fellows will be able to undertake secondments of three to six months to international academic partner institutions. Alternatively, they may collaborate with a non-academic partner institution in the Greater Munich area or elsewhere. Outgoing fellowships will be offered to excellent postdocs with a doctorate from LMU in order to promote the scientific exchange with non-EU countries. Fellows will be seconded to an academic partner institution in a Third Country during an outgoing phase of 12 months and will be reintegrated into a department at LMU during their 12-month return phase. As a rule, incoming and outgoing fellowships will be awarded for two years. In exceptional cases, funding for an additional year may be granted for projects whose scope and originality require additional research time as part of 2+1 fellowships. In summary, the expansion of the LMU Research Fellowships will enhance the career development of international postdocs, extend LMU\u2019s regional and international network of collaborations and contribute to the circulation of outstanding researchers and scientific innovations as part of the realisation of the European Research Area.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2016 - Co-funding of regional, national and international programmes"], "Funding_scheme": ["MSCA-COFUND-FP - Fellowship programmes"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["754388"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2016"]}, -{"Partners": ["STICHTING KATHOLIEKE UNIVERSITEIT"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["Landscape of epigenetic control in early and late germ line development"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["epiGERMetics"], "Technology_Description": "Germ cells have unique role in development. They are the only cells required for the transmission of genetic material from generation to generation in sexually reproducing organisms. This makes them pivotal for the survival of species and ultimately for the propagation of life. Although germ cells undergo extensive cellular differentiation during gametogenesis, they are protected from somatic reprogramming. This requires precise control of transcriptional programs, misregulation of which leads to infertility and developmental defects. Moreover, germ cell-like properties acquired ectopically promote tumor formation. My aim is to understand how germ cell identity is controlled in vertebrates, using zebrafish as a genetic model. My hypothesis is that epigenetic control of gene expression is regulated in both the nucleus and cytoplasm of germ cells. In the nucleus, Polycomb Group (PcG) proteins regulate transcription by establishing repressive chromatin modifications. In the germ cytoplasm, translational regulation by Argonaute proteins, involved in RNA silencing pathways, is pivotal for maintaining germ cell identity. However, the events that facilitate cross-talk between the nucleus and germ cytoplasm are not known. Here, I propose to combine high-end developmental biology techniques with state-of-the art genomic technologies to investigate the cooperation between the PcG complex and Argonaute proteins during germ line development. I believe that the crossing point between my scientific interest (events outside the nucleus) and the expertise of my supervisor (regulation in the nucleus), creates a very solid background for this proposal. It will further develop my interdisciplinary skills and enhance my creative potential by allowing me to look at the regulation of germ cell identity from different angles. I am confident, that this proposal is the perfect stepping stone in becoming an independent scientist and an expert in the field of epigenetic gene regulation.", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["705939"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE BARCELONA INSTITUTE OF SCIENCE AND TECHNOLOGY"], "EU_Contribution": ["EUR 6 478 200"], "Project_Title": ["COFUND BIST POSTDOCTORAL FELLOWSHIP PROGRAMME"], "Total_Cost": ["EUR 12 956 400"], "Country": ["Spain"], "Project_ACR": ["PROBIST"], "Technology_Description": "PROBIST is an ambitious programme offering 61 three-year fellowships to foster excellence in multidisciplinary postdoctoral research at BIST\u00b4s constituent research centres and associated partner institutions (hospitals, private companies, technology centres, and other academic institutions), which will provide opportunities for collaborations and secondments, training, networking activities and other actions to complement the research activities and professional development of the fellows. The PROBIST proposal is presented by the Barcelona Institute of Science and Technology (BIST) as beneficiary.", "To": ["2022-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2016 - Co-funding of regional, national and international programmes"], "Funding_scheme": ["MSCA-COFUND-FP - Fellowship programmes"], "Coordinated_in": ["Spain"], "Activity": ["Other"], "From": ["2017-12-01"], "Project_ID": ["754510"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2016"]}, -{"Partners": ["THE BARCELONA INSTITUTE OF SCIENCE AND TECHNOLOGY"], "EU_Contribution": ["EUR 2 929 920"], "Project_Title": ["COFUND BIST PREDOCTORAL PROGRAMME"], "Total_Cost": ["EUR 5 859 840"], "Country": ["Spain"], "Project_ACR": ["PREBIST"], "Technology_Description": "The PREBIST proposal is presented by the Barcelona Institute of Science and Technology (BIST) as beneficiary. PREBIST is an ambitious programme of 28 four-year fellowships for multidisciplinary pre-doctoral research at BIST\u00b4s constituent research centres and associated partner institutions (hospitals, private companies, technology centres, and other academic institutions), who will provide secondments, training, networking activities and other actions to complement the research activities and professional development of the fellows. ", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2016 - Co-funding of regional, national and international programmes"], "Funding_scheme": ["MSCA-COFUND-DP - Doctoral programmes"], "Coordinated_in": ["Spain"], "Activity": ["Other"], "From": ["2018-01-01"], "Project_ID": ["754558"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2016"]}, -{"Partners": ["FONDATION SCIENCES MATHEMATIQUES DE PARIS"], "EU_Contribution": ["EUR 3 139 200"], "Project_Title": ["International Doctoral Training in Mathematical Sciences in Paris"], "Total_Cost": ["EUR 6 278 400"], "Country": ["France"], "Project_ACR": ["MathInParis"], "Technology_Description": "COFUND MathInParis programme will create and build upon existing networks to attract exceptional Doctoral students coming from abroad, to ensure a very high standard of Doctoral training and to disseminate good practice in terms of selection and mentoring throughout all its Doctoral schools by means of those implemented within this programme. The programme is expected to significantly improve follow-up and mentoring conditions through the presence of dedicated personnel and to develop the scope and modes of provision in Doctoral education. COFUND MathInParis will enhance opening of training in mathematics towards industry and other disciplines, develop new targeted mechanisms for transition of doctoral students to businesses during their training and promote public-private mobility.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2016 - Co-funding of regional, national and international programmes"], "Funding_scheme": ["MSCA-COFUND-DP - Doctoral programmes"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["754362"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2016"]}, -{"Partners": ["ABERYSTWYTH UNIVERSITY"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["A functional analytic approach for the analysis of nonlinear transmission problems"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["FAANon"], "Technology_Description": "The purpose of the research plan is the development of the method called Functional Analytical Approach (FAA) for the analysis of singular perturbations of nonlinear transmission problems. The techniques proposed are based on potential theory and functional analysis and aim at describing the effect of perturbations in terms of real analytic functions. Both perturbations of the shapes of the domains of definition and of the coefficients of the operators will be considered. A special attention will be paid to the case of perforated and periodically perforated domains with shrinking holes and inclusions. The problems addressed are of interest also in view of inter-sectorial applications to the analysis of physical models in fluid dynamic, in elasticity, and in thermodynamic. Concrete applications will be shown in the study effective properties of composite materials, in inverse problems in acoustic and electromagnetic scattering, and in inclusion detection problems. The results obtained represent a novelty with respect to the existing literature for the following reasons:", "To": ["2017-11-30, Grant Agreement terminated |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-12-01"], "Project_ID": ["654795"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["SWANSEA UNIVERSITY"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["When the smoke clears: predicting and preventing catastrophic erosion and flooding after wildfires in volcanic terrains"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["FireAndRiskPrevention"], "Technology_Description": "Wildfires remove protective vegetation, leaving the landscapes vulnerable to catastrophic erosion, landslides and floods. The resulting losses and mitigation costs following wildfires have increased dramatically in the last 30 years due to (i) the population increase, (ii) the rise in fire severity and torrential rains associated with climatic change, and (iii) critical gaps in and limited transfer of knowledge on fire-effects to support decision making. Major advances have been made in the last decade including the development of cost-risk erosion prediction tools, innovative hillslope stabilization treatments and novel approaches to monitor soil redistribution. In Europe, however, their application in post-fire prevention plans is still in its infancy as the necessary soil-specific calibration and effectiveness testing is missing for most terrain types. ", "To": ["2017-12-10, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-08-01"], "Project_ID": ["655993"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITAETSKLINIKUM HAMBURG-EPPENDORF"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Investigating Ror2-dependent non-canonical Wnt signaling in bone remodeling"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["ROR2BONE"], "Technology_Description": "Wnt signaling is composed of the canonical and non-canonical pathways. Canonical Wnt signaling is dependent on \u03b2-catenin activation and has become a major focus for targeting osteoblast-mediated bone formation in the context of treating the debilitating disease osteoporosis. However, much less is known about the role of the non-canonical pathway in bone formation. Unpublished data of the host laboratory demonstrates that targeted deletion of the non-canonical Wnt signaling Receptor tyrosine kinase-like orphan receptor 2 (Ror2) in osteoblasts in mice causes a high bone turnover with increased bone formation and enhanced osteoclast-mediated bone resorption. I thus hypothesize that Ror2 regulates bone remodeling by altering signaling in osteoblasts and their interaction with osteoclasts. In Aim I, I will determine cell autonomous effects of Ror2 on osteoblasts by analyzing cell differentiation, proliferation, survival, and by performing functional studies both in vitro and in vivo. Additionally, since osteoblasts provide pro- and anti-differentiation signals to osteoclasts, Aim I will further explore if Ror2 alters the activity of these signals and investigate the resulting phenotypic changes in osteoclast function. In Aim II, I will undertake an in-depth experimental approach combined with an innovative bioinformatics analysis to investigate the osteoblast-specific non-canonical Wnt signaling cascade downstream of Ror2 after reconstituting Ror2-deficient cells with wild type or Ror2 mutants. Lastly, in Aim III I will directly address the therapeutic potential of Ror2 in several in vivo bone turnover models utilizing a chimeric Ror2-Fc soluble receptor. In summary, I will use state of the art in vivo and in vitro approaches to delineate the downstream Ror2 signaling cascade in osteoblasts and its functional effect on bone remodeling. This fellowship is instrumental in catalyzing career opportunities for me as it provides an ideal environment to reach my full potential.", "To": ["2018-11-02, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-05-01"], "Project_ID": ["658632"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["ISTANBUL MEDIPOL UNIVERSITESI VAFKI", "ISTANBUL SEHIR UNIVERSITESI"], "EU_Contribution": ["EUR 157 845,60"], "Project_Title": ["Characterization and Measurement of Wideband Directional Channels in FM Band For New Efficient Wireless Systems"], "Total_Cost": ["EUR 157 845,60"], "Country": ["Turkey", "Turkey"], "Project_ACR": ["FM-4NXTG"], "Technology_Description": "Motivation: Wireless access is being used extensively in our life. Wireless access enabler, the frequency bands, on the other hand, is very scarce. It is very important that any wireless access system utilizes the frequency at outmost efficiency. One of the poorly utilized wireless bands is the FM Band between 88\u2013108 MHz. The band is being allocated only for relatively high quality audio broadcast around the world. This band has good propagation characteristics and therefore its coverage range and its penetration through buildings are excellent. As FM coverage is so ubiquitous around the world, several applications are already considered to better exploit this useful band: (a) Software defined radios for public safety, (b) New digital audio broadcast services, and (c) the development of an emergency message delivery services. With one of these applications and good propagation characteristics, FM Band can enable a fully connected Europe. ", "To": ["2018-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Turkey"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["706929"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["LEIBNIZ-INSTITUT FUR POLYMERFORSCHUNG DRESDEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "WAGENINGEN UNIVERSITY", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "LEIBNIZ-INSTITUT FUER NEUE MATERIALIEN GEMEINNUETZIGE GMBH", "BASF SE", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "TECHNISCHE UNIVERSITEIT EINDHOVEN", "PANEPISTIMIO PATRON", "Akzo Nobel Decorative Coatings bv", "IMPERIAL CHEMICAL INDUSTRIES LIMITED"], "EU_Contribution": ["EUR 2 822 328,36"], "Project_Title": ["Training in Bio-Inspired Design of Smart Adhesive Materials"], "Total_Cost": ["EUR 2 822 328,36"], "Country": ["Germany", "Germany", "Netherlands", "France", "Germany", "Germany", "United Kingdom", "Netherlands", "Greece", "Netherlands", "United Kingdom"], "Project_ACR": ["BioSmartTrainee"], "Technology_Description": "The last half century has seen a tremendous advancement in adhesives technology and has led to widespread replacement of mechanical fasteners with adhesive bonds (e.g. aircraft, automobile, construction, etc.). Bonding to wet, rough and fouled surfaces, however, remains challenging and adhesive technology is rarely applied for bonding in wet conditions, such as in (orthopaedic) medicine. Therefore, a need exists to educate young researchers in this interdisciplinary research field of controlling adhesion under wet conditions and to bridge the gap between the fundamentals of underwater adhesives and their practice. BioSmartTrainee is set up to provide such training by a combination of three complementary scientific fields: polymer science, adhesion and (fluid)-biomechanics. We aim to (i) extract principles from biological systems and mimic them to design synthetic materials; to (ii) experimentally test their adhesion properties in wet conditions and to (iii) clarify the adhesion mechanisms based on natural examples and theoretical modelling. These innovative adhesives will be useful for reversible attachment to a variety of surfaces in wet environments and, therefore, be highly relevant for products from European industry such as technological adhesives, coatings, tissue adhesives, wound dressings or transdermal delivery devices. This carefully planned research and training program in a network of leading academic and industrial (BASF, AkzoNobel, UGRO) partners will ensure that young researchers are given an excellent training in a pioneering research domain of high scientific and technological relevance, where Europe can take a leading position.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-10-01"], "Project_ID": ["642861"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["UNIWERSYTET MIKOLAJA KOPERNIKA W TORUNIU"], "EU_Contribution": ["EUR 146 462,40"], "Project_Title": ["Breaking the curse of dimension in heavy-element chemistry"], "Total_Cost": ["EUR 146 462,40"], "Country": ["Poland"], "Project_ACR": ["PCCDX"], "Technology_Description": "The acute toxicity and radioactivity of actinide compounds complicate experimental studies of the \u201csoup\u201d of nuclear waste produced in nuclear reactors. This motivates research into computational approaches for determining molecular properties and reactivity of actinide compounds. Unfortunately, the computational resources required by standard quantum chemistry methods grow exponentially with system size, an effect known as the curse of dimension. Since the actinide-containing molecules of relevance to nuclear chemistry contain hundreds of electrons, innovative new approaches that break the curse of dimension must be developed. One such approach models many-electron molecules as collections of noninteracting electron pairs, called geminals. Standard geminal methods are inappropriate for actinide chemistry, however, and must be extended to include (i) computationally efficient ways to account for relativistic effects, (ii) correlations between electrons beyond electron-pairing effects (weak correlation), (iii) electronically excited states, and (iv) the description of unpaired electrons. Specifically, weak correlation will be captured using Coupled Cluster-type approaches, excited states are accessible through an Equation-of-Motion formalism, and open-shell extensions will use generalized quasi-particles as building blocks for the electronic wavefunction. The extended geminal models thus developed will provide the first direct, atomistic, and quantitative computational model for understanding nuclear waste reprocessing and will provide the essential insights that are needed to guide the synthesis of new actinide compounds that can be used to separate actinides from the other components in the \u201csoup\u201d of nuclear waste. The developed models will be robust, computationally cheap, and black-box-like and can be used in many other areas of chemistry and materials physics like lanthanide and transition-metal chemistry, biochemistry, and semiconductor physics.", "To": ["2018-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Poland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-07-01"], "Project_ID": ["702635"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON", "UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 1 499 055"], "Project_Title": ["How retrotransposons remodel the genome during early development and reprogramming"], "Total_Cost": ["EUR 1 499 055"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["TransposonsReprogram"], "Technology_Description": "Retrotransposons (RTNs) are ancient viruses that have stably integrated themselves into mammalian genomes and they now occupy around half of the human or mouse genome. These mobile genetic elements that have coevolved with us drive evolution by creating new genes and plasticity of genomes. Exciting data including ours has shown that even RTNs that are no longer active retain enhancer, promoter or repressor sequences that regulate developmental genes, through largely uncharacterized transcription factors. We have employed CRISPR/Cas9 gene disruption to determine that Zfp37 and Zfp819 bind to and regulate RTNs in mouse embryonic stem cells (ESCs). Identification of these zinc finger proteins (ZFPs) now allows us to ask new questions about how RTNs have been co-opted to orchestrate gene circuits in vitro and in vivo. Both these factors have already been implicated to play a role in reprogramming or genome integrity. ", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["678350"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI PADOVA", "UNIVERSITA DEGLI STUDI DI PADOVA", "UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II."], "EU_Contribution": ["EUR 900 000"], "Project_Title": ["Stable and Chaotic Motions in the Planetary Problem"], "Total_Cost": ["EUR 900 000"], "Country": ["Italy", "Italy", "Italy"], "Project_ACR": ["StableChaoticPlanetM"], "Technology_Description": "The planetary problem consists in determining the motions of n planets, interacting among themselves and with a sun, via gravity only. Its deep comprehension has relevant consequences in Mathematics, Physics, Astronomy and Astrophysics. ", "To": ["2021-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["677793"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["LUNDS UNIVERSITET", "LUNDS UNIVERSITET"], "EU_Contribution": ["EUR 1 750 000"], "Project_Title": ["Drivers and impacts of invertebrate herbivores across forest ecosystems globally."], "Total_Cost": ["EUR 1 750 000"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["ECOHERB"], "Technology_Description": "Forests slow global climate change by absorbing atmospheric carbon dioxide but this ecosystem service is limited by soil nutrients. Herbivores potentially alter soil nutrients in a range of ways, but these have mostly only been recorded for large mammals. By comparison, the impacts of the abundant invertebrates in forests have largely been ignored and are not included in current models used to generate the climate predictions so vital for designing governmental policies", "To": ["2021-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["682707"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["CONSORCI INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["A new therapeutic platform based on nanotechnology to promote T- and B-regulatory networks"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["NANOBreg"], "Technology_Description": "The complexity of autoimmune responses is a barrier to the design of strategies that can selectively purge the immune system of autoreactivity without impairing systemic immunity. Recently, Santamaria et al. have shown that nanoparticles (NPs) coated with type 1 diabetes (T1D)-relevant peptide\u2013MHC (pMHC) complexes can restore normoglycemia in diabetic animals by blunting the diabetogenic autoimmune response without impairing systemic immunity. pMHC class II-NP therapy functions by expanding, in an epitope-specific manner, autoantigen-experienced T-regulatory-1 (TR1) CD4+ T-cells that inhibit the recruitment of other autoantigenic specificities by: (1) suppressing autoantigen-loaded antigen-presenting cells in the pancreatic lymph nodes (PLNs); and (2) promoting the differentiation of B-cells into B-regulatory cells. Importantly, they have shown that human T1D-relevant pMHC class II-NPs also promote human TR1 CD4+ T-cell formation in NSG mice engrafted with peripheral blood mononuclear cells from recent onset T1D patients. ", "To": ["2018-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2016-05-01"], "Project_ID": ["704522"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITE D'AIX MARSEILLE"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Speciation, sources, and fate of atmospheric organic phosphorus over the Mediterranean Sea: A missing piece of the P cycle?"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["PHOSPHOTRAC"], "Technology_Description": "Phosphorus is a critical nutrient affecting primary productivity in large areas in oceanic ecosystems. The principal source of externally supplied nutrients in many marine ecosystems is the atmospheric deposition. As the ocean is an important sink of atmospheric CO2, phosphorus through productivity limitation can indirectly affect global warming by removing more CO2 from the atmosphere. The importance of organic P as a potential pool of bioavailable P in the atmosphere is not widely recognized. It is important to note that the only available data in the literature are the atmospheric measurements of phosphate and total phosphorus, while there are almost no data about the organic P, especially over Mediterranean Sea (MS). The main goal of PHOSPHOTRAC is to shed light on the atmospheric organic P chemical identification and to test the hypothesis that the increased acidification of the atmosphere may significantly impact the bioavailability of organic P. PHOSPHOTRAC proposes new methodologies and modern instrumentation for the identification of organic P compounds in the atmosphere. Most of them are implemented for the first time in atmospheric samples, and they will provide new insights into a nutrient cycle of P in MS. Organic P-rich compounds of interest are DNA, RNA, ATP, phytic acid, phospholipids, degradation products of chemical weapons, organophosphate ester flame retardants and organophosphorous pesticides. Further identification of atmospheric organic P sources in the region will be performed by using the chemical analysis data of specific tracers (ergosterol, anhydrosugars, trace metals), with statistical analysis, and implementation of atmospheric transport model TM4-ECPL coupled with the thermodynamic model ISORROPIA-II. The proposed project is highly interdisciplinary as it combines analytical chemistry, biology, and atmospheric modeling in order to address a question of extreme ecological importance related to climate change in the MS.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["707624"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["ACADEMISCH ZIEKENHUIS GRONINGEN", "ACADEMISCH ZIEKENHUIS GRONINGEN", "BAYERISCHE JULIUS-MAXIMILIANS UNIVERSITAT WURZBURG"], "EU_Contribution": ["EUR 1 531 625"], "Project_Title": ["G-quadruplex DNA Structures and Genome Stability"], "Total_Cost": ["EUR 1 531 625"], "Country": ["Netherlands", "Netherlands", "Germany"], "Project_ACR": ["G4DSB"], "Technology_Description": "Secondary structures such as G-quadruplexes (G4s) can form within DNA or RNA. They pose a dramatic risk for genome stability, because due to their stability they can block DNA replication and this could lead to DNA breaks. In certain cancer cells mutations/deletions are observed at G4s, if a helicase that is important for G4 unwinding is mutated. Nevertheless, G4s are also discussed to be functional elements for cellular processes such as telomere protection, transcription, replication, and meiosis. The aim of this research proposal is to use various biochemical and computational tools to determine which proteins are essential for formation and regulation of G4s. Proposed experiments will gain insights into both \u201ceffects\u201d of G4s, the risk for genome stability and its significant function for the cell. In aim 1 we will elucidate and identify novel proteins that bind, regulate, and repair G4s, especially in the absence of helicases, in vitro and in vivo. Our focus is to understand how G4s become mutated in the absence of helicases, which proteins are involved, and how genome stability is preserved. In aim 2, we will use cutting edge techniques to identify regions that form G4s in vivo. Although there is experimental proof for G4s in vivo, this is not commonly accepted, yet. We will provide solid data that will support the existence of G4s in vivo. Furthermore, we will survey genome-wide when and why G4s become a risk for genome stability. Aim 3 will focus on the in silico observation that G4 structures are connected to meiosis. In this aim we will use a combination of techniques to unravel the biological significance of G4s during meiosis in vivo.", "To": ["2021-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-07-01"], "Project_ID": ["638988"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["STOCKHOLMS UNIVERSITET", "STOCKHOLMS UNIVERSITET"], "EU_Contribution": ["EUR 2 486 951"], "Project_Title": ["Probing the Structure and Dynamics of Water in its Various States"], "Total_Cost": ["EUR 2 486 951,25"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["WATER"], "Technology_Description": "We propose to address some of the most important outstanding questions for a microscopic understanding of water: What is the structure and dynamics of the hydrogen-bonding network that give rise to all the unique properties of water? How is the structure and dynamics affected by temperature, pressure and by perturbation through interaction with solutes and interfaces? Here we point to the opportunity to exploit the completely new avenues that the novel x-ray free-electron lasers open up for probing both structure and dynamics of water from hot temperatures down to the deeply supercooled regime where the anomalous properties become extreme. We plan to further develop fast cooling and ultrafast x-ray probing allowing access to below the homogeneous ice nucleation limit, to probe equilibrium dynamics through probe-probe techniques based on x-ray correlation spectroscopy, to access low-energy vibrational mode dynamics through THz pump and x-ray scattering probe and to transfer x-ray spectroscopies into the time domain.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["667205"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["University of Worcester"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Implementation of a dynamical Pollen Module and the transformations of the pollen including feedbacks in a numerical Weather Forecast Model"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["IPLATFORM"], "Technology_Description": "The main goal of the proposed project is to provide an advanced mathematical model (WRF-BioChem) for modelling the emission, dispersion and concentration of bioaerosols at the regional scale. The model will with this development be able to handle feedback mechanisms between biology, chemistry and weather. The model is developed to go beyond state-of-the-art by developing the mathematical model for oak pollen and by doing it at the species level. The project supported by a three companion projects on grass pollen, fungal spores (Alternaria) and pathogens \u2013 all at species level. These projects deliver the needed resources for detection. As such the mathematical model will be a validated model that will be generally applicable for bioaerosols including pollen, pathogens and fungal spores. Detection of pollen will be carried out by supporting staff and projects using both traditional methods based on optical detection at the genus level and next generation sequencing at the species level. This proposal requires multidisciplinary approach to the problem as pollen appearance and behaviour in the air is dependent on many factors, including meteorological conditions, chemical composition of the atmosphere or surface properties as well as feedbacks between these elements. WRF-Chem currently used in air quality modelling will therefore be adapted for studying transport of bioaerosols in a way consistent with the transport and transformation of other air pollutants. Until now, no atmospheric model is used for the simulation of pollen at the species level in either Europe or in USA. Also, it will be the first time simulations of oak pollen will be possible in Europe or in USA. Also, it will be the first time simulations of oak pollen will be possible in Europe. Finally, it will be the first mathematical model that allows for a full feedback between meteorology, chemistry, bioaerosols and the terrestrial biosphere. The model developments will be implemented in forecasting.", "To": ["2018-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["701753"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["INSTITUTO DE MEDICINA MOLECULAR", "UNIVERSIDAD POMPEU FABRA", "UNIVERSIDAD DE NAVARRA", "TECHNOPHAGE INVESTIGACAO E DESENVOLVIMENTO EM BIOTECNOLOGIA SA", "CENTRO ATLANTICO DEL MEDICAMENTO, SA", "PROTEODESIGN SL"], "EU_Contribution": ["EUR 850 500"], "Project_Title": ["Innovative peptides against cancer and pathogenic bacteria, with advances in science, biopharmaceutical drug development, product market targeting, training , and communication."], "Total_Cost": ["EUR 1 390 500"], "Country": ["Portugal", "Spain", "Spain", "Portugal", "Spain", "Spain"], "Project_ACR": ["INPACT"], "Technology_Description": "INPACT aims at the pre-clinical development of innovative drugs and drug formulations against selected cancers (eg prostate cancer) and pathogenic bacteria (eg S. aureus). The INPACT consortium allies the expertise of both academic and industrial R&D partners that contribute with their own unique technologies to achieve new drugs that are only possible to develop in an integrative effort. Academic partners have unique knowledge and technologies on supercharged viral proteins-derived cell-penetrating peptides (eg from Dengue virus) and ultra-resistant cyclic peptides that may be transferred to the industrial partners, which in turn have specialized proprietary technologies on anticancer and/or peptide drugs\u2019 technologies. The judicious exchange of knowledge among partners will lead to new resistant peptides for trans-barrier delivery of drugs (eg cyclic peptide-drug chimeras) and bacterial killing (both planktonic and biofilms). INPACT includes four leading academic partners (from Portugal, Spain, Australia, and Brazil) and three consolidated biotech SMEs (one from Portugal and two Spain).", "To": ["2019-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Portugal"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-02-01"], "Project_ID": ["644167"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["UNIVERSITAIR MEDISCH CENTRUM UTRECHT"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["Investigating the recognition of a novel ligand by gamma-delta T cells and the translation of this interaction into molecules for future cancer immunotherapy"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["gdTCR-Ligand"], "Technology_Description": "Gamma-delta (gd-)T cells are a fast acting subset of T cells that recognize a wide variety of ligands. In contrast to alpha-beta T cells they are not restricted to classical peptide-MHC antigens. Our preliminary data on a gd-T cell clone shows selective recognition of tumour cells mediated through a novel ligand.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["749010"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["EUROPEAN UNIVERSITY INSTITUTE"], "EU_Contribution": ["EUR 262 269"], "Project_Title": ["MAPS \u2013 Migrants And People Smugglers: A Comparative Study of Smuggling Networks in the Eastern Mediterranean and the Central American corridors"], "Total_Cost": ["EUR 262 269"], "Country": ["Italy"], "Project_ACR": ["MAPS"], "Technology_Description": "To what extent is human smuggling a criminal enterprise driven by solidarity and cooperation? This is the question that my project \u201cMAPS \u2013 Migrants And People Smugglers\u201d addresses through a comparative study \u2013 of the Eastern Mediterranean and the Central American smuggling corridors. Having almost concluded my research in the Eastern Mediterranean corridor, the project will concentrate almost exclusively on the Central American route in order to identify similarities and differences in the organizational structures of smuggling networks, the smuggler-migrant relationship, and the profile of the facilitators. MAPS seeks to make a contribution to studies on Human Smuggling and Irregular Migration, where there is a keen interest in \u2013 yet still insufficient knowledge about \u2013 the interaction between migrants and facilitators and where criminological perspectives still dominate the debate. MAPS adopts a critical perspective and departs from the idea that smugglers obey only to a profit making logic. Inviting instead for a more complex understanding of their roles, it argues that human smuggling is embedded within ethnic networks and local economies, which are grounded on deep notions of solidarity and reciprocity. By expanding current knowledge around smuggling and its related policies, the project also aims to provide an empirical platform for policy engagement. In order to achieve its research aims, I will be based at the San Diego State University (SDSU), located at the proximities of the US/Mexican border and renown for being a centre of excellence on migratory trends from Central American. Here, I will be trained in Critical Criminology, Hispanic Studies and Social Network Analysis under the supervision of Prof Sheldon Zhang. Upon returning to my European host institution, the EUI, I will bring my new skills and further improve my policy and dissemination training under the supervision of Prof Triandafyllidou at the Cultural Pluralism Area of the GGP (EUI).", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["752144"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Thessaly under the Kings: Religion, Society and the Politics of Multiculturalism in Mainland Greece"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["THESUNKIN"], "Technology_Description": "My project titled 'Thessaly under the Kings: Religion, Society and the Politics of Multiculturalism in Mainland Greece\u2019 examines the reorganization of sacred space, the cult practices and the religious beliefs attested in Thessaly from the mid-fourth century to the second century BC. The evidence will be discussed in terms of continuity and change, from the gradual modification of the Thessalian geopolitical and urban landscapes, which was exercised by the Macedonian rulers, to the annexation of the region into the Hellenistic Kingdom of Macedonia, down, finally, to the decline of the Macedonian power and the emergence of Roman control in the region.", "To": ["2017-09-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["658573"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["Netherlands Forensic Institute"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["Chemical Profiling of Inorganic and Pyrotechnic Explosives"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["PyroProf"], "Technology_Description": "The criminal law system has shown interest in the recent scientific developments with respect to chemical profiling of explosives. This approach goes beyond explosive material chemical identification, providing key intelligence to a counter-terrorism or forensic investigation on the basis of chemical clues in the form of impurities and degradation products. Explosive profiling can reveal relationships between samples obtained from a crime scene and material associated with a suspect. If such profiles can be linked to the production process and the raw materials used such intelligence information can even assist law enforcement in stopping attacks from being successfully executed. However, explosive profiling is challenging since it requires suitable analytical strategies, unbiased interpretation of the results, substantial sample collections and comprehensive knowledge on the chemical variation of explosives, precursors and environmental background levels. The main research objective of the PyroProf project is to offer suitable analytical tools for the chemical profiling of inorganic explosives of forensic interest (e.g., ammonium nitrate based and pyrotechnic mixtures) for their use in forensic casework. This project will yield selective sampling strategies, novel separation methodologies by state-of-the-art CE-MS and IC-MS instruments, complementary statistical approaches and databases with further knowledge on explosive, precursor, and background compositions useful for forensic interpretation. This outcome will benefit the experienced researcher to boost his career as a professional researcher in the analytical and forensic chemistry fields as well as will have impact on the European society since the results will be disseminated and used to/by scientific and forensic communities, improving the criminal justice system and the public awareness of the safety and security issued associated with the use of certain explosives (e.g., legal/illegal consumer fireworks).", "To": ["2019-09-03, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-SE - Society and Enterprise panel"], "Coordinated_in": ["Netherlands"], "Activity": ["Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2017-09-04"], "Project_ID": ["747249"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["SCUOLA NORMALE SUPERIORE"], "EU_Contribution": ["EUR 168 277,20"], "Project_Title": ["Gut microbiota impact on brain development and plasticity."], "Total_Cost": ["EUR 168 277,20"], "Country": ["Italy"], "Project_ACR": ["GaMePLAY"], "Technology_Description": "The gut microbiota is characterized by a variety of microorganisms that live in symbiosis with our body and that play a key role in host immune system development and metabolism. Studies in adult germ-free mice suggested the influence of gut commensals on emotional behaviors and stress responses. However, the exact mechanism through which these bacteria affect brain function is largely undiscovered and, their impact on brain development is still a relatively unexplored territory. In my project I propose to investigate how the gut microbiota modulates brain development and plasticity using the established model of mouse developing visual cortex. To find if development and environmental stimuli affect intestinal bacteria, the gut microbiome of mice reared in standard condition (ST) or in an enriched environment (EE) that is known to modulate visual development, will be analyzed at different ages: before weaning (P15), after weaning (P28) and in adulthood (P60) providing for the first time a developmental timeline of the gut microbiota in mice. Then, I will perturb the microbiota composition through antibiotic treatment (ABX) or fecal transplantation (FT) in ST and EE mice, and assess visual cortical function maturation and ocular dominance plasticity. Dendritic spine dynamics analyzed by in vivo two-photon imaging and formation of inhibitory and excitatory neurons will be assessed in the primary visual cortex (V1) as morphological biomarkers of visual cortical development. Finally, in order to find the molecular mechanisms and mediators of gut commensals effect on neuronal circuits, I will perform a transcriptome analysis in V1 of ST and EE mice treated with ABX, or subjected to FT. My research will bring a substantial advancement in the field, revealing how the early interaction between microbiome and host can shape cortical functions, hopefully enabling the discovery of biomarkers for facing neurodevelopmental and psychiatric diseases.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["749697"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["INSTITUTO DE ASTROFISICA DE CANARIAS"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["The DIffuse Galaxy Expansion SignaTures In Various Observables project: understanding the emergence of diffuse, low surface brightness galaxies and the link to their dark matter haloes"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["DIGESTIVO"], "Technology_Description": "I propose to carry out the \u2018DIffuse Galaxy Expansion SignaTures In Various Observables\u2019 (DIGESTIVO) project, a joint theoretical and observational effort alongside observers at the Instituto de Astrofisica de Canarias (IAC), to study the evolution and formation of Low Surface Brightness galaxies (LSBs), including the recently discovered Ultra-Diffuse Galaxies (UDGs). LSBs are extremely dark matter dominated, faint objects hardly distinguishable from the night sky. In the last decade it has became clear that large numbers of LSB galaxies exist, opening a new window on galaxy evolution and formation. How do such diffuse galaxies form and evolve? How are they linked to their dark matter haloes, and how do they fit within the current cosmological model of galaxy formation? ", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2018-02-01"], "Project_ID": ["748213"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FUNDACION PARA LA INVESTIGACION DEL HOSPITAL UNIVERSITARIO LA FE DE LA COMUNIDAD VALENCIANA"], "EU_Contribution": ["EUR 257 191,20"], "Project_Title": ["CD8+ T cell metabolism in anti-tumor response"], "Total_Cost": ["EUR 257 191,20"], "Country": ["Spain"], "Project_ACR": ["Immunometabolomics"], "Technology_Description": "Although cancer immunotherapy has achieved significant breakthroughs in recent years that has positioned it as the most promising approach to treat cancer, its overall efficacy remains limited in the majority of patients. Nutrition-deprived conditions at tumor microenvironment poses significant metabolic challenges to tumor-infiltrating lymphocytes which may contribute to failure of anti-tumor activity. The main objective of the Immunometabolomics project is to understand metabolism in CD8+ T cells, during active effector T cell development and exhaustion, using approaches that go beyond current research which have been mostly focused on glucose/energy metabolism thus disregarding the relevance of anabolic and redox reactions that are crucial in correct cellular function and proliferation. Open-ended metabolomics and metabolic flux analysis studies, in combination with genetic, nutrition and pharmacological manipulations will be employed to study areas of metabolism that have not been previously extensively studied in CD8+ T cells including 1C metabolism. The characterization of metabolism in CD8+ T cells will be gradually performed in models of higher complexity and physiological and clinical relevance from in vitro, to in vivo in genetically engineered mouse models of lung cancer and finally in lung cancer patients. Through understanding CD8+ T cell metabolism, and its modulation in cancer within tumor microenvironment, we aim to develop a basic science foundation for increasing immunotherapy efficiency in cancer through the use of complementary nutritional and/or metabolism-targeted pharmacological approaches.", "To": ["2020-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-07-01"], "Project_ID": ["751423"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["WATERFORD INSTITUTE OF TECHNOLOGY", "UNIVERSITA DEGLI STUDI DI PERUGIA", "UNIVERSITAT POLITECNICA DE CATALUNYA", "TTY-SAATIO", "KOC UNIVERSITY", "UNIVERSITAIR MEDISCH CENTRUM UTRECHT", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM", "IMINDS", "CONSORZIO NAZIONALE INTERUNIVERSITARIO PER LE TELECOMUNICAZIONI"], "EU_Contribution": ["EUR 532 336"], "Project_Title": ["Coordinating European Research on Molecular Communications"], "Total_Cost": ["EUR 532 336"], "Country": ["Ireland", "Italy", "Spain", "Finland", "Turkey", "Netherlands", "United Kingdom", "Belgium", "Belgium", "Italy"], "Project_ACR": ["CIRCLE"], "Technology_Description": "In recent years, several research groups have been created in the emerging research area of molecular communications. This is seen as a fundamental enabler for nano-scale networked devices. The heterogeneity of the biological environments that can host nano-scale communications has produced different proposals (e.g. neuronal networks, molecular diffusion, flow-based carrier mobility) analyzed by means of different research approaches and tools (different analytical models, simulators, lab experiments). For this reason, the need of integrating research activities at an EU level has emerged. The main objective of the CIRCLE is to integrate islands of heterogeneous research activities in a common research framework. The nature of the proposal is therefore strategic for the EU research objectives, highly interdisciplinary, inclusive of any input coming from any research activities that can contribute to identifying a research roadmap for the future years and feasible future exploitation plans.", "To": ["2017-05-31, closed project"], "Meta": [""], "Topic_s": ["FETOPEN-2-2014 - Coordination and Support Activities"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2015-06-01"], "Project_ID": ["665564"], "Call_for_Proposal": ["H2020-FETOPEN-2014-CSA"]}, -{"Partners": ["KUNGLIGA TEKNISKA HOEGSKOLAN", "KUNGLIGA TEKNISKA HOEGSKOLAN"], "EU_Contribution": ["EUR 2 461 947"], "Project_Title": ["Wood Nanotechnology for Multifunctional Structures"], "Total_Cost": ["EUR 2 461 947"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["WoodNanoTech"], "Technology_Description": "\"Materials tend to be either structural or functional. Here focus is on biobased composites combining both aspects, using nanostructured wood templates. Wood is the most widely used biobased material for load-bearing structures, but the range of achievable properties and functions can still be increased. The objective is to develop scalable nanotechnology for wood structures, utilizing its nanocellulosic skeleton. Processing and materials design concepts are developed in the form of a wood nanotechnology toolbox. Focus is on transparent wood for engineering applications, a concept pioneered in my laboratory. Transparent wood can combine load-bearing properties with photonics functions and light weight.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["742733"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["THE SAINSBURY LABORATORY", "THE SAINSBURY LABORATORY", "JOHN INNES CENTRE"], "EU_Contribution": ["EUR 2 491 893"], "Project_Title": ["Retooling plant immunity for resistance to blast fungi"], "Total_Cost": ["EUR 2 491 893"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom"], "Project_ACR": ["BLASTOFF"], "Technology_Description": "Plant NLR-type immune receptors tend to have a narrow spectrum of pathogen recognition, which is currently limiting their value in agriculture. NLRs can recognize pathogen effectors through unconventional domains that have evolved by duplication of an effector target followed by fusion into the NLR. One NLR with an integrated domain is the rice resistance protein Pik-1, which binds an effector of the blast fungus Magnaporthe oryzae via its Heavy-Metal Associated (HMA) domain. We solved the crystal structure of the HMA domain of Pik-1 in complex with a blast fungus effector and gained an unprecedented level of detail of the molecular interactions that define pathogen recognition. This led to the overall aim of this proposal to generate a complete picture of the biophysical interactions between blast fungus effectors and HMA-containing cereal proteins to guide the retooling of the plant immune system towards resistance to blast diseases. M. oryzae is a general cereal killer that infects wheat, barley and rice, which are staple food for a majority of the world population. The central hypothesis of the proposed research is that mutations in cereal HMA-containing proteins will result in broad-spectrum resistance to blast fungi.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["743165"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Transported cultural landscapes: the role of colonization processes in cultural landscape shaping"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["ULISSES"], "Technology_Description": "European landscapes are the result of millennia of socio-cultural exchange through trading, migratory and colonial processes. Societies largely dependent to their local ecosystems and when societies move their landscapes move with them, creating in this way the \u2018so called\u2019 transported landscapes. The Mediterranean Sea has been the cradle and contact route of ancient and influential civilizations, but little is known about how cultural exchanges, migratory and colonial processes contributed to the cultural landscape shaping of Mediterranean environments. This ancient Mediterranean cultural landscape development achieved a universal importance when, during the colonization of America, the transport of European agro-pastoral landscapes configured a shared cultural landscape heritage between both World regions. Despite its significance in cultural landscape shaping, the study of transported landscapes has been poorly addressed so far. ULISSES project is designed to (1)identify the environmental impacts, land-uses and landscape changes involved in migratory and colonization processes during the Holocene and (2) evaluate the role of transported landscapes in the shaping of cultural landscapes both in Europe and overseas. An integrated approach joining multi-proxy palaeoenvironmental analyses (eg. pollen, non-pollen palynomorphs, charcoal analysis, sedimentology), and the study of archaeo-historical sources will be applied in Mediterranean areas of Spain and California (USA). These have been selected for having ancient colonial relationships and for accounting for a long and intense history of colonial, migratory and socio-economic exchanges. By analyzing the cultural dimension of landscapes and the mobility of cultural landscapes, ULISSES will significantly contribute to 1)a better understanding of the European Mediterranean cultural landscape heritage, 2) the formation of European identities and cultures and 3) the influence of European culture and societies in the World", "To": ["2017-09-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2015-10-01"], "Project_ID": ["655659"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich"], "EU_Contribution": ["EUR 175 419,60"], "Project_Title": ["Dynamic Integrated structural and proteomic Analysis of the LUBAC complex and its involvement in NF-\u03baB and inflammation"], "Total_Cost": ["EUR 175 419,60"], "Country": ["Switzerland"], "Project_ACR": ["DIAL-IN"], "Technology_Description": "One of key challenges in current biology is to characterize the genotype to phenotype transition and explain how genomic variation results in specific phenotypes. According to the 'modular biology' paradigm, dynamically regulated multi-protein modules mediate this transition. My project aims at testing this paradigm by applying to a clinically highly relevant case study an integrated workflow of new technologies developed in the host laboratory. In particular, I will focus on a novel ubiquitin ligase complex, linear ubiquitin chain assembly complex (LUBAC), a critical but poorly understood player in several inflammation-related pathways, most notably the canonical NF-\u03baB pathway. Given its key role in the pathogenesis of inflammation, understanding LUBAC will have fundamental biomedical implications. To investigate its structure, function and regulation, I will integrate data generated by mass spectrometry, which is the focus of the Aebersold laboratory, and cryo-electron microscopy (cryo-EM), which is the main expertise I acquired during my PhD. First, I will use quantitative affinity-purification coupled to mass spectrometry (AP-SWATH) to identify the dynamic interactome and the post-translation modifications (PTMs) of LUBAC. I will then define the structure of the complex by combining available atomic models of known LUBAC components, cryo-EM and cross-linking coupled to mass spectrometry (XL-MS). Finally, I will study clinical mutants and map the repercussions of genetic variation at the level of the complex organization, its interactome and of the global proteomic landscape. By these means, I will give a systemic and mechanistic account of the genotype to phenotype transition in clinically relevant scenarios. The output of the project, in line with the Work Programme, will be the production of new knowledge of fundamental biological and medical relevance and the development and validation of enabling technologies at the forefront of molecular biology research.", "To": ["2018-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-11-01"], "Project_ID": ["703759"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["TECHNISCHE UNIVERSITEIT EINDHOVEN"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["Liquid Phase Electron Microscopy of Magnetite"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["LPEMM"], "Technology_Description": "Liquid Phase Electron Microscopy (LPEM) is a state-of-the-art analysis technique for real-time observations of nanoscale processes in liquids. As a research tool, it is unique in its ability to observe material formation pathways in complex environments. Consequently LPEM is expected to solve grand challenges in materials science; however, several obstacles need to be overcome before this technique can fully impact the whole materials science community. In the proposal LPEMM, I intend to address these multidisciplinary problems through the study of an ideal, but industrially relevant material system, namely magnetite. Magnetite is the most magnetic naturally occurring substance on earth, and of great technological interest in areas such as water purification, biomedicine and data storage. The magnetic properties of magnetite are determined by particle size, shape and organization, which in Nature is controlled though the process of biomineralization. In Magnetotactic bacteria biomineralizations occurs in confined, complex compartments called magnetosomes. I will replicate this environment inside the electron microscope and record the process with nanometer resolution, providing the first ever real-time videos of the magnetite formation. In collaboration with an industrial partner FEI Company, I will determine optimal microscope configuration and imaging conditions for LPEM based on particle motion, contrast and liquid layer thickness. The proposed research will provide a unique insight into magnetite biomineralization allowing the design of new synthetic routes to form magnetite under ambient conditions, with control over particle size, shape and organization. In a broader context summation of this research will provide a clear platform for the investigation of material formation in complex environments by LPEM; thereby obtaining unprecedented details on the formation pathway and establishing new synthetic routes to complex materials.", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-03-01"], "Project_ID": ["748105"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["DEUTSCHES KREBSFORSCHUNGSZENTRUM", "DEUTSCHES KREBSFORSCHUNGSZENTRUM"], "EU_Contribution": ["EUR 2 500 000"], "Project_Title": ["Endogenous barcoding for in vivo fate mapping of lineage development in the blood and immune system"], "Total_Cost": ["EUR 2 500 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["BARCODED-CELLTRACING"], "Technology_Description": "The immune system is a complex ensemble of diverse lineages. Studies on in-vivo-hematopoiesis have until now largely rested on transplantation. More physiological experiments have been limited by the inability to analyze hematopoietic stem (HSC) and progenitor cells in situ without cell isolation and other disruptive manipulations. We have developed mouse mutants in which a fluorescent marker can be switched on in HSC in situ (inducible fate mapping), and traced HSC lineage output under unperturbed conditions in vivo. These experiments uncovered marked differences comparing in situ and post-transplantation hematopoiesis. These new developments raise several important questions, notably on the developmental fates HSC realize in vivo (as opposed to their experimental potential), and on the structure (routes and nodes) of hematopoiesis from HSC to peripheral blood and immune lineages. Answers to these questions (and in fact the deconvolution of any tissue) require the development of non-invasive, high resolution barcoding systems. We have now designed, built and tested a DNA-based barcoding system, termed Polylox, that is based on an artificial recombination locus in which Cre recombinase can generate several hundred thousand genetic tags in mice.", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-07-01"], "Project_ID": ["742883"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["AALTO-KORKEAKOULUSAATIO", "AALTO-KORKEAKOULUSAATIO"], "EU_Contribution": ["EUR 2 499 999"], "Project_Title": ["Field driven materials for functions, dissipation, and mimicking Pavlovian adaptation"], "Total_Cost": ["EUR 2 499 999"], "Country": ["Finland", "Finland"], "Project_ACR": ["DRIVEN"], "Technology_Description": "During the recent years, biological materials have extensively inspired materials scientists towards new properties, e.g., for composites, photonics, and wetting. The future grand challenge is to mimic biological active materials towards new properties that commonly have not been connected with man-made materials. Due to the biological complexity, conceptually new approaches are needed in materials science. In the project DRIVEN, field-driven dissipative out-of-equilibrium self-assemblies are developed in the colloidal and molecular scale. In the proposal, instead of using chemical fuels to drive dissipative self-assemblies, which is ubiquitous in Nature, imposed fields are here used to drive the system out-of-equilibrium towards new assemblies and functions. The project show steps with growing risks towards highly ambitious new materials mimicking aspects from active biological materials.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["742829"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN"], "EU_Contribution": ["EUR 941 760"], "Project_Title": ["Political Concepts in the World"], "Total_Cost": ["EUR 1 883 520"], "Country": ["United Kingdom"], "Project_ACR": ["POLITICO"], "Technology_Description": "The POLITICO PhD programme will build on the success of the interdisciplinary training provided by the University of Aberdeen\u2019s Centre for Citizenship, Civil Society and the Rule of Law (CISRUL), which specializes in the global application of political ideas.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2016 - Co-funding of regional, national and international programmes"], "Funding_scheme": ["MSCA-COFUND-DP - Doctoral programmes"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["754326"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "NATURAL ENVIRONMENT RESEARCH COUNCIL"], "EU_Contribution": ["EUR 2 817 554"], "Project_Title": ["WArm Climate Stability of the West Antarctic ice sheet in the last INterglacial (WACSWAIN)"], "Total_Cost": ["EUR 2 817 554"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom"], "Project_ACR": ["WACSWAIN"], "Technology_Description": "Recent papers predict the loss of most of the West Antarctic Ice Sheet (WAIS) by 2500 if CO2 emissions and rising global temperatures are not controlled. It is critical to test whether the models making such worrying predictions are realistic. I will do this by obtaining new data from the last interglacial (LIG, 130,000-115,000 years ago) to assess the response of the WAIS to comparable warmth. ", "To": ["2022-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2017-08-01"], "Project_ID": ["742224"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["THE HEBREW UNIVERSITY OF JERUSALEM", "THE HEBREW UNIVERSITY OF JERUSALEM"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["A novel pharmaceutical treatment for nonalcoholic fatty liver disease"], "Total_Cost": ["EUR 150 000"], "Country": ["Israel", "Israel"], "Project_ACR": ["NAFLDcure"], "Technology_Description": "Development of anti-microRNA therapeutic for nonalcoholic fatty liver disease", "To": ["2018-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["737590"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["FORSCHUNGSINSTITUT FUR MOLEKULARE PATHOLOGIE GESELLSCHAFT MBH", "FORSCHUNGSINSTITUT FUR MOLEKULARE PATHOLOGIE GESELLSCHAFT MBH"], "EU_Contribution": ["EUR 2 325 659"], "Project_Title": ["Understanding the evolution of regeneration-permissive gene expression and positional memory in Axolotl limb regeneration"], "Total_Cost": ["EUR 2 325 659"], "Country": ["Austria", "Austria"], "Project_ACR": ["RegGeneMems"], "Technology_Description": "Molecular studies of development in diverse animal models have revealed the remarkably conserved set of morphogens governing growth and patterning of body axes and organ fields. Equally astounding is the diversity of form and function arising from the implementation of these morphogens. The systematic analysis of well-defined traits in closely related species has revealed how changes in gene regulatory sequences and their trans-acting factors have yielded diversity. An important future challenge is to understand, at the genome level, the evolution of animal form in situations where such a rich set of closely related species may not be available. ", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Austria"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-01-01"], "Project_ID": ["742046"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 995 354"], "Project_Title": ["Microfluidic Approaches mimicking BIoGeological conditions to investigate subsurface CO2 recycling"], "Total_Cost": ["EUR 1 995 354"], "Country": ["France", "France"], "Project_ACR": ["Big Mac"], "Technology_Description": "The management of anthropogenic CO2 will be one of the main challenges of this century given the dramatic impact of greenhouse gases on our living environment. A fascinating strategy to restore the advantages of stored CO2 as a raw material would be to consider a slow biological upgrading process of CO2 in deep geological formations. ", "To": ["2022-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-11-01"], "Project_ID": ["725100"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "UNIVERSITY OF LEICESTER"], "EU_Contribution": ["EUR 1 933 165"], "Project_Title": ["Feeding Anglo-Saxon England: The Bioarchaeology of an Agricultural Revolution"], "Total_Cost": ["EUR 1 933 165"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom"], "Project_ACR": ["FeedSax"], "Technology_Description": "By the time of the Norman Conquest in 1066, England\u2019s population was again comparable to that of Roman Britain and included substantial urban centres. By 1200, England was more densely populated than ever before. Such population growth was mirrored across much of Europe. It drove the expansion of towns and markets and was fed, literally, by an increase in agricultural productivity that involved a fundamental reorganization of the countryside. The social, economic and demographic consequences of this reorganization were so far-reaching that it has often been described as an \u2018agricultural revolution\u2019. At the heart of this proposal is the question, how and when was this revolution achieved? FeedSax will effect a breakthrough in understanding this critically important period in Europe\u2019s agricultural history by generating new, direct evidence for changing land-use from the excavated remains of crops, animals and farms.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["741751"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 1 462 304"], "Project_Title": ["Global Firms and Global Value Chains: Measurement and Mechanisms"], "Total_Cost": ["EUR 1 462 304"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["GLOBALFIRMS"], "Technology_Description": "The growing fragmentation of production across firms and countries has revolutionized international trade in recent decades. Firms today choose which production stages to conduct themselves and which to outsource to other parties, which to complete at home and which to offshore abroad. Known as global value chains (GVCs), this phenomenon creates new challenges and opportunities for individual firms and aggregate economies. Of primary policy interest are the implications of GVCs for growth, the transmission of shocks across firms and borders, and the design of economic policies. Yet academic research has faced two major challenges: poor measurement and poorly understood mechanisms.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["724880"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["THE HEBREW UNIVERSITY OF JERUSALEM", "THE HEBREW UNIVERSITY OF JERUSALEM"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["TIGIT therapy for cancer treatment"], "Total_Cost": ["EUR 150 000"], "Country": ["Israel", "Israel"], "Project_ACR": ["TIGITtherapy"], "Technology_Description": "Treating tumors with immune-related therapies is one of the most exciting and promising advancements made in the past decade. Cancer immunotherapy drugs have captured nearly 50% of the overall oncology drugs market. TIGIT is an important checkpoint inhibitory receptor discovered by our group in 2009. It is constitutively expressed by various immune cells and its expression is further increased on tumor infiltrating lymphocytes (TILs). TIGIT recognizes two main ligands, PVR and Nectin2 that are highly expressed on various tumors. Blockage of TIGIT on TILs either alone or in combination with another checkpoint inhibitory receptor, PD-1, leads to increased T and Natural Killer (NK) cell activity in vitro and inhibited tumor growth in vivo. We developed 9 different anti-TIGIT mAbs during my BacNK ERC advanced grant and previously. In the POC grant TIGITtherapy, which already attracted interest from several bio pharma companies, I propose testing which of the 9 anti-TIGIT mAbs and TIGIT-Ig are able to antagonize TIGIT activity.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["721317"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["RUHR-UNIVERSITAET BOCHUM", "RUHR-UNIVERSITAET BOCHUM"], "EU_Contribution": ["EUR 1 998 717"], "Project_Title": ["Dynamics in Buddhist Networks in Eastern Central Asia, 6th-14th Centuries"], "Total_Cost": ["EUR 1 998 717"], "Country": ["Germany", "Germany"], "Project_ACR": ["BuddhistRoad"], "Technology_Description": "The objective of this proposal is to create a new framework to enable understanding of the complexities in the dynamics of cultural encounter and religious transfer in pre-modern Eastern Central Asia\u2014the vast area extending from the Taklamakan desert to Northeast China. This region was the crossroads of ancient civilisations. Its uniqueness was determined by complex dynamics of religious and cultural exchanges gravitating around an ancient communication artery, known as the Silk Road. Buddhism was one major factor in this exchange; its transfer predetermined the transfer of adjacent aspects of culture. The religious exchange involved a variety of cultures and civilisations, which were modified and shaped by their adoption of Buddhism. This process overrode the ethnic and linguistic boundaries of the Buddhist universe. One specific aspect of this process was the rise of the local forms of Buddhism. This project intends to investigate such Buddhist localisations between the 6th\u201314th centuries. ", "To": ["2022-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["725519"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["ROYAL COLLEGE OF SURGEONS IN IRELAND", "ROYAL COLLEGE OF SURGEONS IN IRELAND"], "EU_Contribution": ["EUR 1 781 622,96"], "Project_Title": ["Investigating the meanings and mechanisms of psychotic experiences in young people: a novel, mixed-methods approach"], "Total_Cost": ["EUR 1 781 622,96"], "Country": ["Ireland", "Ireland"], "Project_ACR": ["iHEAR"], "Technology_Description": "Up to one fifth of young people have had the experience of psychotic symptoms, such as hearing voices when there is no-one around, or seeing visions. We now know that young people who experience these symptoms are at increased risk of developing psychotic disorders in adulthood. We also know that these young people are at higher risk of a range of co-morbid disorders such as depression and anxiety, and particularly suicidal behaviours. On the other hand, many of these young people will remain well and, for them, the psychotic experiences were merely a transitory phenomenon. ", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["724809"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN", "LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN"], "EU_Contribution": ["EUR 2 500 000"], "Project_Title": ["Non-sequence models for tokenization replacement"], "Total_Cost": ["EUR 2 500 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["NonSequeToR"], "Technology_Description": "Natural language processing (NLP) is concerned with computer-based processing of natural language, with applications such as human-machine interfaces and information access. The capabilities of NLP are currently severely limited compared to humans. NLP has high error rates for languages that differ from English (e.g., languages with higher morphological complexity like Czech) and for text genres that are not well edited (or noisy) and that are of high economic importance, e.g., social media text.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["740516"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET", "KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 2 211 015"], "Project_Title": ["Self Organization in Competition and Diversity"], "Total_Cost": ["EUR 2 211 015"], "Country": ["Denmark", "Denmark"], "Project_ACR": ["SOURCE"], "Technology_Description": "\"At all scales, biology presents an astounding diversity of discrete states or species that coexist with each other long times.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["740704"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 149 963"], "Project_Title": ["Aligned Roll-to-Roll Shear Coating of Nanotubes"], "Total_Cost": ["EUR 149 963"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["ARENA"], "Technology_Description": "Carbon Nanotubes (CNTs) are considered to be one of 21st century\u2019s most promising materials and over the past decade, tremendous scientific advances have been achieved in the synthesis and processing of these materials. However, the uptake of CNTs by high-tech industry is hampered by a lack of high-throughput processes to structure CNTs into aligned and densely packed assemblies. This is key to fabricate next generation CNT devices, and to date, the CNT community is still struggling to achieve this, especially over large areas. ", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["737627"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["WEIZMANN INSTITUTE OF SCIENCE", "WEIZMANN INSTITUTE OF SCIENCE"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Learning and Anxiety in Amygdala-based Neural Circuits"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Israel", "Israel"], "Project_ACR": ["LearnAnx_CircAmyg"], "Technology_Description": "Major advances were made in understanding circuits that underlie aversive emotional learning. The majority gained by using classical associative models, mainly tone/context-shock conditioning. Failure to extinguish the response or to discriminate from other safe stimuli (generalization), form two main animal models for human anxiety-disorders and post-traumatic-stress. These simple yet powerful approaches enabled cutting-edge techniques in rodents to unveil amygdala circuitry and its connectivity with the medial-prefrontal-cortex. Yet, we have less understanding of the mechanisms that underlie elaborated behavioural models of mal-adaptive behaviour, as well as less understanding of neural codes and computations in the evolutionary-expanded primate amygdala. Our lab recently embarked on exploring these venues by pioneering physiological studies of generalization and extinction protocols in primates. The goal of the current project is to develop behavioural models of complex learning and maladaptive behaviour, and then examine and shed light on the underlying computations in primate amygdala-PFC circuit. We design a novel rule-based learning task, and examine its acquisition, extinction, generalization and exploration-exploitation trade-off in dangerous environments. Specifically, the concepts of rule learning and exploration-exploitation tradeoff form novel insights and aspects of [mal-]adaptive behaviours, and will suggest new animal models of learned anxiety. We record dozens of neurons in the amygdala and prefrontal-cortex simultaneously using deep multi-contact arrays, supplemented by stimulation to address functional connectivity, and development of modelling approaches for the behaviour and neural codes. We posit that the development of more [complex] models is crucial and the next logical step in achieving translation of animal models of anxiety disorders, as well as in understanding basic mechanisms behind the rich repertoire of emotional behaviours.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["724910"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS"], "EU_Contribution": ["EUR 251 857,80"], "Project_Title": ["Acoustical and Canonical Fluid Dynamics in numerical general relativity"], "Total_Cost": ["EUR 251 857,80"], "Country": ["United Kingdom", "United States"], "Project_ACR": ["ACFD"], "Technology_Description": "The motion of strongly gravitating fluid bodies is described by the Euler-Einstein system of partial differential equations, combining fluid dynamics with general relativity. Centuries after their advent, the solution to these equations remains mathematically and computationally difficult, and the break-down of well-posedness on the boundary interface between fluid and vacuum remains a challenging open problem. The problem manifests itself in numerical simulations of binary neutron-star inspiral. The program will focus on formulating and implementing novel, well-posed Hamiltonian hydrodynamic schemes, suitable for inspiral simulations and gravitational-wave detector applications, with promising mathematical and computational applications in academia and industry. The scheme will use a variational principle by Carter-Lichnerowicz stating that barotropic fluid motions are conformally geodesic, a corollary of Kelvin's circulation theorem stating that initially irrotational flows remain irrotational, and Christodoulou's acoustic metric approach adopted to 3+1 numerical general relativity, in order to evolve the canonical momentum of a fluid element via Hamilton's equations. The recent observation of the inspiral and merger of binary black holes by the LIGO-Virgo collaboration, which marked the beginning of the era of gravitational wave astronomy, makes this work very timely: additional observations from binary neutron star or black hole\u2013neutron star binary mergers are anticipated over the next years. The proposed research represents a coherent program aimed at mathematically and computationally exploring the theory of neutron stars, in order to improve our understanding of fundamental physical laws and reveal how nature operates on scales where our current understanding breaks down. Improvements in calibrated semi-analytical neutron-star gravitational waveforms can be directly deployed in the LIGO-Virgo search and parameter estimation pipelines.", "To": ["2020-08-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-08-15"], "Project_ID": ["753115"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KATHOLIEKE UNIVERSITEIT LEUVEN", "Stichting Sanquin Bloedvoorziening", "PROTOBIOS OU", "ICOSAGEN AS"], "EU_Contribution": ["EUR 1 464 397,92"], "Project_Title": ["Innovative training network: Immunoprofile-directed stratification of patients with the autoimmune disorder thrombotic thrombocytopenic purpura"], "Total_Cost": ["EUR 1 464 397,92"], "Country": ["Belgium", "Netherlands", "Estonia", "Estonia"], "Project_ACR": ["PROFILE"], "Technology_Description": "The PROFILE Innovative European Industrial Doctoral programme will develop improved tools for stratification of patients with the autoimmune disorder acquired thrombotic thrombocytopenic purpura (TTP). Patient stratification is needed in order to further develop personalized medicine approaches for human disorders. Therefore, a detailed understanding of the disease at the molecular level is needed. Furthermore, implementation of a robust set of novel biomarkers is essential for stratification of patients. Also, highly flexible platforms to rapidly develop novel therapeutics are crucial to further boost the field of personalized medicine. The research program is embedded in a unique translational training program, which emphasizes clinical needs as a driving force for development of novel, innovative diagnostics and therapeutics (for personalized medicine). There is intersectoral knowledge transfer between academia and companies at the European level as 6 different EU Member states are involved in the network either as beneficiary or partner organization. The PROFILE network will allow 6 early stage researchers to follow this unique translational training. They will be trained in the clinic to identify clinical needs, in academia where they will contribute to a scientifically ambitious project and in the non-academic sector where they will be trained in a novel technologies and commercializing bioassays endowing them with an unique PROFILE for further advancing personalized medicine in Europe.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-EID - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-EID)"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-10-01"], "Project_ID": ["675746"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 200 194,80"], "Project_Title": ["Modelling Arctic Biogenic Volatile Organic Compounds emissions (MABVOC)"], "Total_Cost": ["EUR 200 194,80"], "Country": ["Denmark"], "Project_ACR": ["MABVOC"], "Technology_Description": "Arctic is warming at approximately twice the global speed, which could result in drastic changes in the arctic biosphere as well as its potential feedbacks to the atmosphere. Several important but uncertain feedbacks are related to biogenic volatile organic compounds (BVOC) emissions from arctic plants and high organic soils. BVOC influence climate systems through changing atmospheric compositions (oxidant and aerosols); however, the magnitudes and directions of these feedbacks are still poorly quantified for the Arctic. This project, MABVOC, aims to quantify BVOC emissions for the pan-Arctic region by using a process-based dynamic ecosystem model (LPJ-GUESS), combined with leaf, soil and ecosystem levels observations from the Arctic, and to further predict potential changes of emissions under climate change. A series of model developments will be proposed in this project to explicitly consider arctic plants emission features as well as soil BVOC dynamics. The host group, conducting large and novel field observations about arctic BVOC, will provide needed field data and frontier understanding that will be implemented in the model. I will combine my expertise in arctic ecosystem modelling to numerically link BVOC fluxes with different ecosystem processes, which enables me to provide quantifications of different factors\u2019 impacts on emissions to the host group. The high degree of complementary expertise between the host and I will guarantee the quality and smoothness of this project. The updated emission estimates from the Arctic will pave a way for reassessing arctic BVOC-mediated feedbacks to the climate system. Furthermore, the proposed model developments in this project will be transferable to the larger modelling community to reduce uncertainties in arctic applications. The integration of experiences between field investigators and ecosystem modellers in this project will lead to a productive and valuable exchange of knowledge on both sides.", "To": ["2018-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-12-01"], "Project_ID": ["707187"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM", "TECHNISCHE UNIVERSITEIT EINDHOVEN", "UNIVERSIDADE DO MINHO", "JYVASKYLAN YLIOPISTO", "NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO", "STICHTING VU", "ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA", "PERSONAL GENOMICS SRL"], "EU_Contribution": ["EUR 2 873 941,92"], "Project_Title": ["Physical Activity and Nutrition INfluences In ageing"], "Total_Cost": ["EUR 2 873 941,92"], "Country": ["United Kingdom", "Netherlands", "Portugal", "Finland", "Netherlands", "Netherlands", "Italy", "Italy"], "Project_ACR": ["PANINI"], "Technology_Description": "Life expectancy is increasing dramatically, but the period of good health (healthspan) enjoyed by most is not keeping pace, with implications for health, social care, and pensions resulting in estimated costs more than doubling by 2050. Thus, understanding the many factors that contribute to healthy ageing versus frailty, and validating interventions and influencing policy to promote healthy ageing is a cross-cutting research priority in Europe. Given the considerable impact of lifestyle factors on healthy ageing and disease, there is a surprising lack of innovative multi-disciplinary training and research examining the influence of physical activity and nutrition on age-related changes at gene to societal level. PANINI will address this gap by coordinating research laboratories across Europe to focus on cutting-edge ageing and health research through training 11 ESRs across scientific disciplines to create a holistic approach to the challenge of ageing in the 21st Century. PANINI is a European Training Network with 8 world-leading beneficiaries working on Healthy Ageing and 10 non-academic partners carefully selected for quality and range of sectors. These vary in size including 1 large nutrition company, 5 SMEs, 2 charities, 1 healthcare partnership and 1 EU Joint Research Centre. PANINI\u2019s vision is to implement multidisciplinary cross-sectoral research and training of a new cohort of researchers taking a radically innovative approach to overcome the challenge of unhealthy ageing. The main goals of PANINI are to: integrate expertise from basic biomedical science and technology to applied clinical practice; standardise measurements across the network to create a toolkit and shared dataset; provide multidisciplinary training secondments to expose ESRs to healthcare and industry research settings and other laboratories; disseminate widely the shared and individual project findings; and use these to develop a policy document to promote healthy ageing in Europe.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-01-01"], "Project_ID": ["675003"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["STICHTING VU"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["Stepping forward in understanding the Metabolic Cost of Human Walking"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["Metabolic cost of walking"], "Technology_Description": "The mechanisms underlying metabolic cost of walking are unclear. This is important not only because they provide fundamental insight in human movement, but they are also essential to reduce increased cost of walking in the elderly and impaired. To understand these mechanisms, it is required to know the link between energetics at the human level and the energetics at the muscle level. Whereas the energetics at the human level is experimentally accessible, that at the muscle level is not. Current estimations greatly overestimate actual metabolic cost and hence there is no basis understanding metabolic cost of walking. ", "To": ["2017-03-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-04-01"], "Project_ID": ["655457"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE UNIVERSITY OF NOTTINGHAM", "UNIVERSITEIT MAASTRICHT", "KAROLINSKA INSTITUTET", "UNIVERSITY COLLEGE LONDON", "VRIJE UNIVERSITEIT BRUSSEL", "UNIVERZITA KARLOVA", "STICHTING VU", "I MAS D Y EMPLEO SERVICONSULTING SL", "STICHTING VUMC"], "EU_Contribution": ["EUR 3 878 757"], "Project_Title": ["Interdisciplinary Network for Dementia Utilising Current Technology (INDUCT)"], "Total_Cost": ["EUR 3 878 757"], "Country": ["United Kingdom", "Netherlands", "Sweden", "United Kingdom", "Belgium", "Czech Republic", "Netherlands", "Spain", "Netherlands"], "Project_ACR": ["INDUCT"], "Technology_Description": "Dementia raises complex challenges for people with dementia, their families, and society. The European Parliament has called for investment in high quality, innovative technology research to improve dementia care but so far there has been little benefit because research has generally been limited, small scale and methodologically flawed. In particular: the poor understanding between research and business of how people with dementia use technology means new applications are designed without an in-depth appreciation of people\u2019s needs, preferences and limitations; there is little knowledge about practical, psychological and social barriers and facilitators to implementation making it hard to get results into practice; there is a serious shortage of research trained professionals who combine expertise on dementia care research and technology. In conjunction with INTERDEM the world\u2019s largest network of psychosocial research for people with dementia this ITN will: develop a European multi-disciplinary, intersectoral educational research framework for Europe, to comprehensively train 15 early stage researchers (ESRs) to PhD level; provide the research evidence to show how technology may improve care and quality of life for people with dementia; and provide the European workforce with a much needed new generation of excellent research trained professionals. The objectives of INDUCT are to: determine practical, cognitive & social factors to improve usability of technology; evaluate the effectiveness of specific contemporary technology; trace facilitators & barriers for implementation of technology in dementia care. Using advanced methods in applied health research (e.g. randomised controlled trials, qualitative studies) INDUCT will provide the evidence needed to demonstrate how to make dementia care technology more usable, more effective, and better implemented in practice, culminating in an international consensus guideline for improving policy and practice.", "To": ["2020-02-29, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["676265"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["STICHTING VU"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["Institutional Innovation for Adapting to Climate Change in Water Governance within Cities"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["INNOVCITIES"], "Technology_Description": "This research will address the problem of the currently insufficient level of institutional innovation in water governance systems in the context of climate change. Climate change creates urgent need for adaptive water governance that can anticipate and respond to increasing pressures on water systems within human society. Cities are a key locus of attention. Institutional innovation is needed (e.g. policy change, new organisational setups, new inter-organisational arrangements). However, knowledge of the types of institutional innovation required and the mechanisms (e.g. political, institutional) by which it emerges is lacking. Therefore I will address the question: What types of institutional innovation are required for adapting to climate change in water governance within cities, and how can we better understand why and how they emerge? This will involve: (1) global assessment of institutional innovation in water governance in 30 cities across 6 continents to identify broad patterns and best practices across the world; (2) comparative case study analysis of 3 \u2018innovative\u2019 cities across 3 continents in contrasting global contexts to attain deeper understanding of dynamics underpinning innovation; and (3) dissemination of results and policy recommendations to enable innovation in cities in Europe and globally. By addressing this urgent research and policy problem, the MCSA fellowship will enable me to develop new expertise, academic and policy networks, and research profile that will position me as a leading emerging scholar in the field of water governance and climate change adaptation. The research will contribute to the knowledge based economy of Europe by providing critical new academic and policy insights to safeguard against water-related vulnerabilities in cities under climate change, and contribute to addressing two of the European Commission\u2019s \u2018Grand Challenges\u2019 (i.e. climate action; and innovative and reflective societies).", "To": ["2017-10-18, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-10-19"], "Project_ID": ["659065"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["STICHTING VU"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["Decoding the neural mechanism of human spatial cognition using behavioural and hemodynamic signals"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["DecodeRemapping"], "Technology_Description": "The aim of this research is to understand space constancy, that is the mechanisms used by the brain to build a stable and continuous percept of our environment despite frequent movements of our sensory receptors (eyes, ears). For example, each time we move our eyes, the image of the outside world sweeps across the retina, yet we see the world as stable. Studies using single cell recording in animals have shown that some visual neurones predict what the world will look like after an eye movement by remapping their receptive fields to the place they will occupy following the movement. In my previous studies I developed behavioural tools that allowed me to model remapping in human as an attentional process. Even though my findings in humans were largely consistent with the results obtained from single cell recordings in animals, there was no possible way to establish a direct link between these data. Recent methodological advances in functional imaging, both in terms of techniques and data analysis make this possible. By combining my tools with novel imaging analysis of human population receptive fields, I aim to determine the mechanisms our brains use to stabilise our percept of the world for visual and auditory objects. Using hemodynamic (fMRI) and behavioural (gaze recording) signals I will decode the organisation of the multi-sensory spatial maps. I aim to determine the role of attention for space constancy, to establish innovative methods and procedures for investigating human spatial cognition, and to reconcile human and animal neurosciences findings by providing precise neural information of the maps and the neural mechanisms of human spatial navigation. This interdisciplinary project will constitute a unique opportunity to combine my expertise with state-of-the-art methods. I will have the chance to expend my skills, putting me on the best track to pursue a future independent research career with a multi-faceted profile of psychologist and neuroscientist.", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["704537"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["STICHTING VU"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["Process Invigoration through Model Embellishment"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["PRIME"], "Technology_Description": "The objective of this research project is to enhance business process (BP) model comprehension in European organisations through dynamic process invigoration. Analysis and improvement of BPs are key to organisations\u2019 cost efficiency and competitiveness. A growing number of organisations in Europe implement BP management solutions to analyse and automate their processes. BP models are invaluable to define, control, improve and communicate BPs. BP models abstract a dynamic phenomenon in the form of a static representation, thus they are often difficult to comprehend. In this research, I aim at redefining the BP model comprehension problem and developing innovative solutions through a synergetic usage of process modeling and multimedia disciplines. In this way, models will be dynamically invigorated and presented to business professionals in a comprehensible manner. To fulfil the overall objective, related literature will be reviewed; BP model invigoration techniques will be designed for eight different embellishment components; the techniques will be evaluated through industrial experiments and field studies; an open source BP model invigoration tool will be developed; and results will be disseminated in European academy and industry. Eventually, organisations from various domains in Europe can utilize their BP models in a better way by using the freely available PRIME tool to invigorate their processes. This will create an opportunity to increase organisational efficiency throughout Europe. This project will contribute to my career development in many ways. I will obtain regular training on scientific and transferable skills through interdisciplinary trainings with my supervisor and other scholars, courses in research schools, and the preparation of publications. Collaboration and networking will be enhanced through joint studies with scholars and industry, enabled by the supervisor\u2019s previous collaborations as well as my experiences.", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["660646"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CHARITE - UNIVERSITAETSMEDIZIN BERLIN"], "EU_Contribution": ["EUR 2 547 762"], "Project_Title": ["IMMUNOBIOLOGY OF LYMPHOID STROMAL CELLS"], "Total_Cost": ["EUR 2 547 762"], "Country": ["France", "France", "Germany"], "Project_ACR": ["STROMA"], "Technology_Description": "In 1984, Nossal wrote \u2018\u2018A readership consisting of primarily anatomists has every right to question the favorite sport of research workers in cell immunology. This is to take a lymphoid tissue and totally destroy its beautiful and elaborately designed architecture to obtain simple cell suspension of lymphocytes, which are then asked to do more or less all the jobs of the original anatomic masterpiece\u2019\u2019. Growing evidence that lymph node (LN) stromal cells control the motility, activation and survival of lymphocytes has reinforced this view. These architectural cells assemble in 3D networks that regulate LN homeostasis and control its ability to remodel during inflammation. Understanding stromal cell biology is thus mandatory to our full comprehension of the immune system but this ambitious objective is technically challenging. As the complexity of the LN cannot be modelled in culture, knowledge gained from in vitro experiments is limited and will not address many relevant questions related to the biology of LN stromal cells, in particular (i) the elucidation of their origin and the precursor/product relationships that link them, (ii) the determination of their behavior in inflamed LNs and (iii) their subsequent fate in LNs that have returned to homeostasis. To this aim, I have developed several original, cutting-edge multicolor fluorescent reporter mouse models and computational modeling approaches to map the fate of single stromal cells and their progeny in situ. Using this innovative approach, my group will investigate the spatio-temporal behavior and molecular cues that orchestrate the development and dynamics of the major LN stromal cell populations in vivo, at steady state and under inflammatory conditions, at the single cell level. Because the proposed studies will unravel the precursor/product relationships linking the various stromal cell types, we anticipate to provide the first \u201cPhylogenetic tree\u201d of LN stromal cell development and remodeling.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["647257"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["STICHTING VU", "STICHTING VU"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["High-resolution microscopy without lenses: a new generation of imaging technology"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["Lensless"], "Technology_Description": "Lensless imaging is an elegant approach to microscopy, in which a sharp image of an object is retrieved by numerical means rather than by actual optical components such as lenses. Such an approach allows high-resolution imaging using only a light source and an image sensor. Multi-wavelength phase retrieval (Witte et al., patent application PCT/NL2013/050618) provides a general framework for lensless imaging, which allows the development of surprisingly simple yet high-resolution imaging devices. By detecting wavelength-dependent differences in wave propagation, I have recently shown that amplitude and phase of an object field can be reconstructed with high contrast and resolution. This approach works for complex objects in both reflection and transmission. As such, lensless microscopes have advantages in size, cost, robustness and simplicity, and provide a powerful alternative to conventional imaging systems in many applications.", "To": ["2020-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-05-01"], "Project_ID": ["637476"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["CHARITE - UNIVERSITAETSMEDIZIN BERLIN", "CHARITE - UNIVERSITAETSMEDIZIN BERLIN"], "EU_Contribution": ["EUR 1 483 720"], "Project_Title": ["Prenatal Stress and Programming of Newborn and Infant Telomere Biology and Cellular Aging"], "Total_Cost": ["EUR 1 483 720"], "Country": ["Germany", "Germany"], "Project_ACR": ["PrenatStressAging"], "Technology_Description": "The long-term consequences of exposure to excess stress on the initiation and progression of many age-related diseases are well established. The period of intrauterine life represents among the most sensitive developmental windows, at which time the effects of stress may be transmitted inter-generationally from a mother to her as-yet-unborn child. The elucidation of mechanisms underlying such effects is an area of intense interest and investigation. Aging, by definition, occurs with advancing age, and age-related disorders result from exposures over the life span of factors that produce and accumulate damage. The novel concept advanced in this proposal is that the establishment of the integrity of key cellular aging-related processes that determine variation across individuals in the onset and progression of age-related disorders may originate very early in life (in utero) and may be plastic and influenced by developmental conditions. We propose that telomere biology and the epigenetic DNA methylation-based aging profile (DNAmAGE) represent candidate outcomes of particular interest in this context. A prospective, longitudinal cohort study of 350 mother-child dyads will be conducted from early pregnancy through birth till one year of age. Specific hypotheses about the effects of maternal stress and maternal-placental-fetal stress biology on newborn and infant telomere length, telomerase expression capacity, and DNAmAGE will be addressed. Serial measures of maternal psychological, behavioral and physiological characteristics will be collected across gestation using an innovative ecological momentary assessment (EMA) based real-time, ambulatory sampling protocol. The proposed study will help identify new strategies for risk identification and primary and secondary interventions to augment current efforts to prevent, delay and ameliorate age-related disorders.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["678073"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["STICHTING VU", "STICHTING VU"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["THAWing permafrost: the fate of Soil Organic Matter in the aquatic Environment"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["THAWSOME"], "Technology_Description": "As the Arctic permafrost region warms, its large organic carbon (OC) pool becomes vulnerable to decomposition. This generates greenhouse gases (GHG) that in turn fuel increased surface warming: the permafrost carbon feedback. Higher temperatures will jump-start the coupling between the carbon and hydrological cycle, allowing for the introduction of previously frozen OC pools in aquatic systems. This lateral, or horizontal, aquatic flux remains largely unknown in contrast to the relatively well-studied vertical flux, GHG emission on land. ", "To": ["2021-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-12-01"], "Project_ID": ["676982"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["STICHTING VU", "STICHTING VU"], "EU_Contribution": ["EUR 1 499 482,50"], "Project_Title": ["The Human Behavioral Immune System: Consequences for Health and Innovation"], "Total_Cost": ["EUR 1 499 482,50"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["HBIS"], "Technology_Description": "Modern innovations such as soap, condoms, and indoor plumbing have allowed billions of people to reduce their contact with viruses and bacteria and, as a result, dramatically increase length and quality of life. But how did members of the genus homo avoid pathogens for the two million years that preceded these technological innovations and, more broadly, discoveries that infectious disease is caused by microbes? And, importantly, how do any natural behavioral defenses against pathogens impact our behavior in the modern world? Recent research and theory in the field of evolutionary psychology suggests that natural selection has shaped a human behavioral immune system (HBIS)\u2014a suite of psychological mechanisms, ranging from aspects of our olfactory systems (e.g., that detect specific chemical compounds) to our emotion systems (e.g., the emotion disgust) and our learning systems (e.g., conditioned aversions to foods) that are coordinated for a common function: to detect and motivate the avoidance of pathogens. Given that myriad universal human behaviors connote some pathogen risk\u2014including interpersonal contact, mating, and eating\u2014gaining a holistic understanding of the HBIS has the potential to offer critical new insights into multiple fundamental aspects of human nature. Here, I utilize an interdisciplinary approach to answer three foundational, yet currently opaque questions concerning the nature of the HBIS, including: (1) Where does trait variation in HBIS activation come from? (2) What effect does the HBIS have on behavior when cues to pathogens are detected? and (3) How does the HBIS facilitate learning of avoidance and rejection? To answer these questions, I propose an array of methodologically diverse studies to investigate how trait HBIS activation shapes rejection versus acceptance of innovations, how state HBIS activation can be harnessed to promote the use of health-promoting technologies, and how the HBIS can be leveraged for shaping dietary behavior.", "To": ["2021-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-07-01"], "Project_ID": ["680002"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["STICHTING VU"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["Integrating memories: Exploring knowledge integration enhancement at the intersection of education and neuroscience"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["Integrating Memories"], "Technology_Description": "Learning about the world is most effective when we can relate new information to previously learned knowledge structures, but underlying neurocognitive processes are still poorly understood. To successfully structure our knowledge, we can integrate separately learned instances by inferring an association between them. In the brain, this integration of old and new memories has been suggested to be facilitated by the reinstatement of prior knowledge structures during new learning, but it remains unclear exactly how reinstatement enables effective building of such knowledge structures. Especially in real-world educational settings it is vital to understand how to effectively build knowledge, but thus far direct translation of neuroscientific insights to educational practice has proven challenging. ", "To": ["2018-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-12-01"], "Project_ID": ["704506"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["STICHTING VU", "STICHTING VU"], "EU_Contribution": ["EUR 1 998 655"], "Project_Title": ["Social Cognition in Adolescents: Brain Networks and Social Networks"], "Total_Cost": ["EUR 1 998 655"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["SCANS"], "Technology_Description": "The forming of social bonds is an evolutionary imperative, and a rich target for empirical research. Social scientists have scrutinized the structure of the elaborate social networks that characterize today\u2019s society. Neuroscientists have elucidated the brain mechanisms underlying our ability to navigate this social world. Yet, these research lines have been largely separated. This proposal aims to integrate social network research and social brain research, focusing on adolescence as the most dynamic phase shaping the interplay between social networks and the social brain. Social development in adolescents is clearly driven by maturation of specific social-cognitive functions; yet these functions are manifest in, and moulded by, interpersonal relationships within social networks. I aim to clarify how changes in the social brain relate to changes in social network position and structure during adolescent development. This can be achieved by using the quantitative tools of social network analysis in conjunction with the experimental approach of social neuroscience. I plan to investigate a cohort of approximately 1000 adolescents nested in 50 classes in a longitudinal design with 6 measurements over 3 years; fMRI investigating task-related functional activation and connectivity is conducted yearly in a subsample of 100. The neural and behavioural correlates of social cognition are investigated using experimental tasks tapping i) understanding others and ii) interacting with others; social behaviour is charted through ecological momentary assessment techniques; social networks are mapped using surveys and digital information acquired routinely via mobile phones (mobile sensing). This approach clarifies how during a crucial developmental phase the social brain shapes the social environment, and vice versa, the social environment influences maturation of the social brain.", "To": ["2021-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-02-01"], "Project_ID": ["648082"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["STICHTING VU", "STICHTING VU"], "EU_Contribution": ["EUR 1 499 268,75"], "Project_Title": ["Peptide-derived bioavailable macrocycles as inhibitors of protein-RNA and protein-protein interactions"], "Total_Cost": ["EUR 1 499 268,75"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["PEP-PRO-RNA"], "Technology_Description": "The objective of this proposal is the elucidation of general principles for the design of bioavailable peptide-derived macrocyclic compounds and their use for the development of inhibitors of protein\u2012protein (PPI) and protein\u2012RNA interactions (PRI). Over the last decade, drug discovery faced the problem of decreasing success rates which is mainly caused by the fact that numerous novel biological targets are reluctant to classic small molecule modulation. In particular, that holds true for PPIs and PRIs. Approaches that allow the modulation of these interactions provide access to therapeutic agents targeting crucial biological processes that have been considered undruggable so far. Herein, I propose the use of irregularly structured peptide binding epitopes as starting point for the design of bioactive macrocycles. In a two-step process high target affinity and bioavailability are installed:", "To": ["2021-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["678623"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["CHARITE - UNIVERSITAETSMEDIZIN BERLIN", "CHARITE - UNIVERSITAETSMEDIZIN BERLIN"], "EU_Contribution": ["EUR 1 870 588"], "Project_Title": ["Personalized whole brain simulations: linking connectomics and dynamics in the human brain"], "Total_Cost": ["EUR 1 870 588"], "Country": ["Germany", "Germany"], "Project_ACR": ["BrainModes"], "Technology_Description": "Background. We have detailed maps of brain structure and function, yet are lacking understanding of how the highly connected units interact and give rise to mental processes. The Virtual Brain (TVB), a whole brain simulation framework, aims to bridge that gap. Yet it is still developing. We are proposing here breakthrough advances that reveal mechanisms of brain function and foster collaboration between research groups. Vision. Clinical applications that simulate individual patient brains and predict trajectories of recovery or decline or test therapies to select the best one for that person. Goal. Using biologically realistic brain models and multimodal functional and structural imaging data to elucidate control mechanisms of the human brain in aging. A database collects key data and allows identifying most generic models and mechanisms below the spatial and temporal resolution of non-invasive imaging techniques taking into account the complex interaction in the brain that without a model would be impossible to keep track of. Objectives. 1) Parameter optimization for large parameter space search and a library of dynamical regimes linking dynamical regimes and underlying mechanisms to biological (cognitive) age. 2) Identifying the role of intrinsic plasticity for network reconfigurations in the resting state and its age dependency. 3) Model based identification of task related plasticity mechanisms and their functional consequences for network reconfigurations in coordination learning in aging. 4) An interactive tool that provides access to the dynamical regimes library and makes pre-computed simulations easily accessible allowing researchers to benefit and learn from existing work. Impact. Understanding development, aging and brain disorders from the perspective of disruption of information processing architectures provides an opportunity for new interventions that re-establish control in brain pathology hence posing a breakthrough in the health and biotech sector.", "To": ["2021-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-08-01"], "Project_ID": ["683049"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["CHARITE - UNIVERSITAETSMEDIZIN BERLIN"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Intentions in Action: Establishing the neural causes of intentional action"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["Intentions in Action"], "Technology_Description": "The neuroscientific study of intentional action has produced puzzling and contradictory results: intentions show up at a variety of brain locations, and up to ten seconds before a decision has been made. Recently, it has been argued that intentions do not underlie voluntary action at all. At the same time neural states have been found that could be correlated with future actions, suggesting a role for intentions after all. The proposed project suggests that the cause of these seemingly contrasting results lies in the heterogeneous composition of everyday actions, consisting of both immediate and future-directed components. The proposed research promises to go to the bottom of this controversy by investigation what types of actions can be accomplished without discrete states like intentions, and for what types of actions intentions are needed. It will do so by looking for common factors in brain states underlying actions using functional Magnetic Resonance Imaging. Particularly, it will be investigated whether similarity in motor acts, actions, or contexts are crucial for finding commonalities in brain states. ", "To": ["2017-07-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-08-01"], "Project_ID": ["657605"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["STICHTING VU", "STICHTING VU"], "EU_Contribution": ["EUR 2 497 664"], "Project_Title": ["The Proton Size Puzzle: Testing QED at Extreme Wavelengths"], "Total_Cost": ["EUR 2 497 664"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["QED-PROTONSIZE"], "Technology_Description": "A key component of the Standard Model is Quantum Electrodynamics (QED). QED explains e.g. the anomalous magnetic moment of the electron and small energy shifts in the energy structure of atoms and molecules due to vacuum fluctuations. After decades of precision measurements, especially laser spectroscopy in atomic hydrogen, QED is considered the most successful and best-tested theory in physics. However, in 2010 precision spectroscopy in muonic-hydrogen (where the electron is replaced with a muon) has lead to discrepancies in energy level structure that cannot be accounted for. If QED is considered correct, then one way of interpreting the results is that the size of the proton is different in normal (electronic) hydrogen by as much as 4% (a 7 sigma effect) compared to muonic hydrogen. Despite great theoretical and experimental efforts, this 'proton size puzzle' is still unsolved.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["695677"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["STICHTING VU", "STICHTING VU"], "EU_Contribution": ["EUR 2 500 000"], "Project_Title": ["Probing Physics beyond the Standard Model from Molecules"], "Total_Cost": ["EUR 2 500 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["NEWPHYS-MOLECULES"], "Technology_Description": "The Standard Model of physics is incomplete. Gravity is not understood at the quantum level, dark matter and dark energy are not explained, and (string)-theories searching to cover these shortcomings are only consistent in higher-dimensional spaces, while only four of those dimensions are observed. The mystery of finely tuned strengths of the fundamental forces, providing us with a Universe of complexity, remains unexplained. This calls for new physics that can also be explored at the atomic scale in the low energy domain. That is the paradigm underlying the present proposal: Effects of new physics \u2013 either related to hitherto unknown particles or to symmetry-breaking phenomena \u2013 will manifest themselves as minute shifts in the quantum level structures of atoms and molecules, in minute drifts over time or dependencies on environmental conditions.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["670168"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["STICHTING VU"], "EU_Contribution": ["EUR 167 610,60"], "Project_Title": ["Beta-cell inflammation and dysfunction induced by bacterial translocation"], "Total_Cost": ["EUR 167 610,60"], "Country": ["Netherlands"], "Project_ACR": ["BETA-BACT"], "Technology_Description": "Type 2 diabetes (T2D) has risen to epidemic proportions resulting in major morbidity and mortality. In addition to insulin resistance (i.e. impaired insulin action), impaired function and destruction of the insulin-producing beta cells form the direct cause for hyperglycemia and T2D, and causes the progressive course of disease. As such, due to continuous beta-cell destruction, many patients require treatment with exogenous insulin therapy. Clearly, therapies that may halt or reverse this detrimental process are warranted.", "To": ["2018-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["708193"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["STICHTING VU", "STICHTING VU"], "EU_Contribution": ["EUR 1 999 891,25"], "Project_Title": ["Improving the accuracy and reliability of electronic structure calculations: New exchange-correlation functionals from a rigorous expansion at infinite coupling strength"], "Total_Cost": ["EUR 1 999 891,25"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["corr-DFT"], "Technology_Description": "By virtue of its computational efficiency, Kohn-Sham (KS) density functional theory (DFT) is the method of choice for the electronic structure calculations in computational chemistry and solid-state physics. Despite its enormous successes, KS DFT\u2019s predictive power and overall usefulness are still hampered by inadequate approximations for near-degenerate and strongly-correlated systems. Crucial examples are transition metal complexes (key for catalysis), stretched chemical bonds (key to predict chemical reactions), technologically advanced functional materials, and manmade nanostructures. ", "To": ["2020-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-08-01"], "Project_ID": ["648932"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["STICHTING VU", "DANMARKS TEKNISKE UNIVERSITET", "KOBENHAVNS UNIVERSITET", "UNIVERSITY COLLEGE LONDON", "LUMICKS B.V."], "EU_Contribution": ["EUR 3 567 025"], "Project_Title": ["Super-resolution visualisation and manipulation of metaphase chromosomes"], "Total_Cost": ["EUR 3 567 025"], "Country": ["Netherlands", "Denmark", "Denmark", "United Kingdom", "Netherlands"], "Project_ACR": ["CHROMAVISION"], "Technology_Description": "CHROMAVISION aims to develop a pioneering chromosome imaging and manipulation platform that will fuel the next decades of structural chromosome research. Chromosomal abnormalities are characteristic of many disorders such as cancer, impaired fertility due to maternal aging, and neurological disorders such as fragile X syndrome. If humanity is to fully understand the wide range of diseases that are associated to errors in cell division, we must be able to further 'zoom in' on healthy and diseased chromosomes in all their complexity. The CHROMAVISION platform will allow molecular biologists to automatically isolate individual chromosomes from small tissue or cell samples and have these delivered to a super-resolution microscope. Chromosome isolation and delivery is achieved by an opto-fluidic chip that is able to trap, visualise and lyse individual cells and separate metaphase chromosomes from cell lysate. Single chromosomes can be \u201chand-selected\u201d and brought into focus of the Super-Resolution Correlative Tweezers Fluorescence Microscope (CTFM-SR3D) that is developed in CHROMAVISION. This instrument will for the first time enable 3D, super-resolution, real-time metaphase chromosome observation and manipulation studies under near-physiological conditions. The technique will push the boundaries of what is currently possible in microfluidics and super-resolution microscopy and combine these into a single powerful approach for chromosome studies. Furthermore, the platform will be applied in CHROMAVISION to address key challenges in clinical and fundamental chromosome research, potentially resulting in breakthrough discoveries. Better imaging and understanding of the chromosomal mechanisms will contribute to our knowledge of the etiology of human diseases and aid drug discovery. The platform will also have large clinical value, allowing identification and monitoring of e.g. cancer heterogeneity.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-1-2014 - FET-Open research projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-06-01"], "Project_ID": ["665233"], "Call_for_Proposal": ["H2020-FETOPEN-2014-2015-RIA"]}, -{"Partners": ["STICHTING VU", "STICHTING VU"], "EU_Contribution": ["EUR 1 870 135"], "Project_Title": ["The molecular genetic architecture of educational attainment and its significance for cognitive health"], "Total_Cost": ["EUR 1 870 135"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["EdGe"], "Technology_Description": "Since many social and economic outcomes are moderately heritable, it is in principle possible to discover genetic variants associated with them. Such discoveries could yield new insights into the causal pathways underlying human behaviour, the complex interplay of environmental and genetic factors, and the relationship between socio-economic traits and health.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["647648"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["STICHTING VU", "STICHTING VU"], "EU_Contribution": ["EUR 1 962 679"], "Project_Title": ["It\u2019s not my fault I am aggressive, they picked on me: How early peer relations affect DNA methylation and neurocognitive development in children"], "Total_Cost": ["EUR 1 962 679"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["socio-bio interplay"], "Technology_Description": "Think about the day you took your child to kindergarten for the first time. You were worried. Worried about the social experiences of your child. Would peers like your child, or would it get bullied, or rejected by classmates? ", "To": ["2020-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-07-01"], "Project_ID": ["646594"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["STICHTING VU"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["Quantum coherence in photosynthesis: towards single-molecule light-conversion devices"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["QuantumPhotosynth"], "Technology_Description": "Photosynthesis performed by plants, algae and photosynthetic bacteria is the biological process that transforms solar energy into chemical energy with high quantum efficiency. A complete understanding of the factors that modulate the efficiency of this process is a challenge centered at the nexus of fundamental physics and biology, and obtaining that knowledge could pave the way for the design of the next generation of cheap and highly-efficient light-conversion devices. The main aim of this project is to understand how quantum coherence modulates the efficiency of photosynthesis. Quantum coherence is likely to be involved in not only the first ultrafast stages of excitation energy transfer in the photosynthetic light harvesting antenna but also in the charge separation process in the photosynthetic reaction center by coupling to specific vibrational states of this pigment-protein complex (Romero et al, Nature Physics 10, 676-682, 2014). Here we propose to use time-resolved coherent anti-Stokes Raman spectroscopy and two-dimensional photon echo spectroscopy to demonstrate the specific vibrational modes that sustain quantum coherence at the single molecule level. Time-resolved anti-Stokes Raman spectroscopy will provide an insight into the specific vibrations in the molecule that lead to sustained quantum coherence in the charge separation steps of photosynthesis. Results will be confirmed using two-dimensional photon echo spectroscopy and rationalized in a Redfield theory framework. To assess the role of energetic disorder, reaction centers will also be characterized using a combination of single-molecule techniques in order to correlate the quantum coherence arising at the single-molecule level with the efficiency of the whole ensemble. To achieve this, a new technique capable of quantifying quantum coherence at the nanoscale will be developed. This new technique and its applications will deeply impact quantum biology and other fields.", "To": ["2017-09-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["660521"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["STICHTING VU"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["The travelling astronomers. International collaborations after World War II and the reorganization of European astronomy (1953-1985)"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["ISHTAR"], "Technology_Description": "This research project investigates the history of astronomy in Europe after World War II. In the period between 1953 and 1985, a number of international collaborations were undertaken by several European countries, with the aim of strengthening astronomical research in terms of its capacity and facilities. These collaborations culminated in the construction of powerful observational facilities and the implementation of programmes for cooperation in professional research. In this respect, the initiatives taken from 1953 to 1985 inaugurated a new era of European astronomy. Indeed, in this period research facilities were made available in both hemispheres, new research networks were created, and there was a new attitude towards scientific cooperation.", "To": ["2017-05-31, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-06-01"], "Project_ID": ["656139"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["STICHTING VU", "STICHTING VU"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Releasing Prisoners Of The Paradigm: Understanding How Cooperation Varies Across Contexts In The Lab And Field"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["COOPERATION"], "Technology_Description": "Cooperation is essential for mitigating conflict between individual and collective interests in relationships and groups, such as providing public goods and conserving resources. Most research testing psychological and economic theory of cooperation has applied a highly specific lab method (e.g., the prisoner\u2019s dilemma) that unnecessarily constrains the applicability of research findings. The discrepancies between cooperation observed in the lab and field can be due to variation in interdependence. Two limitations of lab studies to generalizing findings to the field are that (1) lab studies contain interdependence that differs from reality and (2) in the field people lack knowledge about their objective interdependence with others \u2013 and must infer their interdependence. I propose two inter-related research programs that test hypotheses derived from Functional Interdependence Theory on how objective and perceived interdependence affect cooperation. Project 1 applies meta-analysis to test hypotheses about how variation in objective interdependence across lab studies moderates the effectiveness of strategies to promote cooperation. Because Project 2 involves a pioneering effort to catalogue and analyze the 60 year history of research on cooperation, I will apply these efforts to develop an international, multidisciplinary institution and open access database for cataloguing studies in a way that facilitates scientific progress. Project 2 (a) develops a measure of perceived interdependence, (b) observes the interdependence people encounter in their daily lives, (c) tests two models of how people think about interdependence, and (d) innovates and applies a method to test hypotheses about factors that influence accuracy and bias in perceptions of interdependence. To maximize the ecological validity of research findings, I study cooperation in different samples (students, romantic couples, and employees) with the use of multiple methods (survey, experimental, and field).", "To": ["2020-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-08-01"], "Project_ID": ["635356"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["STICHTING VU"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["Urban networks: multidisciplinary research into the formation of early urban societies in Campania (Italy)"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["URBANet"], "Technology_Description": "Living in cities has been one of the most transformative innovations in human history: it has heavily impacted social and political interaction between people, and has significantly changed the relationship between man and his natural environment. Understanding why people in the past started living together in cities in the first place, provides crucial tools for the study of urban life from a comparative perspective.", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["702511"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["STICHTING VU"], "EU_Contribution": ["EUR 418 560"], "Project_Title": ["Scientific Top Training in Antimicrobial Research"], "Total_Cost": ["EUR 837 120"], "Country": ["Netherlands"], "Project_ACR": ["AIMMS STAR-PLUS"], "Technology_Description": "The Amsterdam Institute for Molecules, Medicines and Systems (AIMMS, www.aimms.vu.nl) offers an innovative selection procedure for international Top Master's Students to train a new generation of top scientists who can contribute to solving the problem of bacterial, viral and parasitic diseases.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2015-DP - Marie Sk\u0142odowska-Curie Co-funding of regional, national and international programmes (COFUND-DP)"], "Funding_scheme": ["MSCA-COFUND-DP - Doctoral programmes"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["713669"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2015"]}, -{"Partners": ["STICHTING VU", "STICHTING VU"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Launching Acoustic Force Spectroscopy - unlocking the potential of biomolecular bungee jumping"], "Total_Cost": ["EUR 150 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["ACOFORS"], "Technology_Description": "ACOFORS has been designed with the ultimate goal of preparing commercialisation of Acoustic Force Spectroscopy (AFS). AFS is a completely new and powerful technique for determining biomolecular mechanics and structure of single molecules such as DNA and proteins. These studies are performed on a large scale by biologists and within pharmaceutical companies for e.g. drug discovery and development. Current technologies for force spectroscopy (FS) represent a $50+ million market, but are expensive, require high levels of specialism and are laborious. AFS, invented in the laboratory of Prof. Wuite, is much simpler to use, can be operated in high-throughput mode and can become available at relative low cost. As such, AFS vastly expands the possibilities of FS and makes it available to a much wider community. This makes AFS a very attractive technology for science and business, both from the perspective of the user and of the seller. ", "To": ["2016-06-30, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2014 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-07-01"], "Project_ID": ["665656"], "Call_for_Proposal": ["ERC-2014-PoC"]}, -{"Partners": ["STICHTING VU", "STICHTING VU"], "EU_Contribution": ["EUR 147 500"], "Project_Title": ["Imaging with Photon Counting: Reduced costs, increased dynamic range"], "Total_Cost": ["EUR 147 500"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["PhotonCount"], "Technology_Description": "Optical methods and fluorescent proteins to probe and manipulate cellular and subcellular processes have proven to be a major driving force behind many recent breakthroughs in biology and medicine. Recent developments in photonics have led to increased spatial and temporal resolution and now allow the study of single identified synaptic contacts between neurons as well as large-scale neuronal networks. Brain tissue strongly scatters light. Thereby, the amount of light emitted by fluorescent probes in small structures inside neuronal tissue that reaches the microscope objective is small. Fluorescence imaging in living tissue, as I use in my ERC-funded research program, is therefore limited by low signal-to-noise levels. One approach in increasing the level of such weak fluorescence is to increase the excitation power, but this has the undesirable effect of bleaching the fluorescence faster and damaging the cell. Another approach is to optimize the fluorescence collection by using high-end microscope objectives in the 20,000 eur range with improved light transmission, high numerical aperture and low magnification that can collect fluorescence more efficiently. Although these objectives brought a significant improvement to imaging applications, physical limitations in their design cannot offer anymore a similar qualitative improvement as previously. Since there is a great need to further improve biological imaging, the present proof of concept application aims to achieve this by developing advanced, but low-cost, electronics for the optical detection of weak fluorescence signals through Photon Counting, and bring this technology to the market.", "To": ["2016-03-31, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2014 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-04-01"], "Project_ID": ["665522"], "Call_for_Proposal": ["ERC-2014-PoC"]}, -{"Partners": ["STICHTING VU", "STICHTING VU"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Development of an Anger Regulation Tool for Hand-Held Devices"], "Total_Cost": ["EUR 150 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["ART"], "Technology_Description": "Our research team at the Amsterdam Emotion regulation Lab (emotionregulationlab.com) has recently established that avoidance movements can lower anger and aggression among individuals with chronic anger management problems. Building on and extending these findings, we propose to develop, test, and market an interactive application that runs on mobile devices such as smart phones and tablets. This Anger Reduction Tool (ART) will consist of a \u2018serious game\u2019 that trains people to make avoidance movements to angry faces. The ART will be commercialized through a freemium model, such that it will be made freely available, while users can purchase additional functionalities using bio- and neuro-feedback modules. The ART will be marketed to mental health professionals with clients who are not willing or able to respond to traditional cognitive interventions, such as high school children or lower-educated violent offenders. By harnessing the possibilities of smart technology, the ART allows people to become co-managers of their (mental) health and well-being.", "To": ["2018-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2015 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["693623"], "Call_for_Proposal": ["ERC-2015-PoC"]}, -{"Partners": ["INSTITUTO SUPERIOR TECNICO"], "EU_Contribution": ["EUR 100 397,25"], "Project_Title": ["Action understanding in human and robot dyadic interaction"], "Total_Cost": ["EUR 100 397,25"], "Country": ["Portugal"], "Project_ACR": ["ACTICIPATE"], "Technology_Description": "Humans have fascinating skills for grasping and manipulation of objects, even in complex, dynamic environments, and execute coordinated movements of the head, eyes, arms, and hands, in order to accomplish everyday tasks. When working on a shared space, during dyadic interaction tasks, humans engage in non-verbal communication, by understanding and anticipating the actions of working partners, and coupling their actions in a meaningful way. ", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Portugal"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["752611"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS"], "EU_Contribution": ["EUR 164 653,20"], "Project_Title": ["Quantum Enhanced Sensing with Cold Atoms"], "Total_Cost": ["EUR 164 653,20"], "Country": ["Greece"], "Project_ACR": ["QUESCA"], "Technology_Description": "Atom sensors based on cold atoms have demonstrated great potential in precision measurements both in applied technology and in fundamental science. The main limitation is now the quantum projection noise originating from the counting of uncorrelated atoms. This limit can only be broken by entangling the probe atoms and creating squeezed states. We propose a novel scheme for generating squeezing in ultra-cold atomic ensembles via quantum-non-demolition measurements based on the cavity-aided measurement of the Faraday optical rotation that light experiences as it travels through the atomic medium. This method holds the promise of realizing a significant squeezing with a medium-finesse optical cavity without the use of additional optical interferometers. It outperforms conventional detection schemes based on absorption imaging by allowing smaller dead time between consecutive measurements. Applications include atomic clocks and inertial sensors, which can be used for technical applications (gravitational geodesy, gravimetry for oil, gas and rare metal exploration and cavity detection in construction) and for fundamental physics experiments (gravitational wave detectors, Einstein Equivalence test and gravitational tests of the standard model).", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Greece"], "Activity": ["Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555"], "From": ["2017-08-01"], "Project_ID": ["750017"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["AKVAPLAN-NIVA AS"], "EU_Contribution": ["EUR 196 400,40"], "Project_Title": ["Biological Impact of Oil Pollution in Arctic and Deep-sea Environment"], "Total_Cost": ["EUR 196 400,40"], "Country": ["Norway"], "Project_ACR": ["BIOPADE"], "Technology_Description": "\"The increase demand of oil, associated with the depletion of easily exploitable oil deposits is leading the oil industry to intensify the search for new oil areas and exploit deposits previously considered as economically unprofitable. These new oil research areas are mostly located in Arctic waters and in the \"offshore\" areas in deep waters. However, very few studies have investigated the biological impacts of oil contamination in these very specific areas. Practically, the research actions will estimate the potential synergistic effect of oil, warming and hypoxia on a key Arctic species, polar cod Boreogadus saida (Work package 1, WP1).The project will then will focus on the impacts of the soluble fraction of oil on the metabolism of deep benthic species, in particular Lophelia pertusa and Eurythenes gryllus (WP 2). WP3 will consist of an applied study in order to validate two experimental set-ups which could make possible the assessment of the impact of oil in deep-sea environments. Finally, WP4 will be devoted to provide recommendations to perform a relevant NEBA in Arctic and deep-sea areas. The complementarities between the applicant and the supervisors profiles, associated with partner organizations skills ensure the realization of this innovative project and the dissemination and exploitation of the different results.\"", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-SE - Society and Enterprise panel"], "Coordinated_in": ["Norway"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-10-01"], "Project_ID": ["750511"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["Ecological and Evolutionary consequences of predator-prey phenological match-mismatch driven by climate change"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["EcoEvoClim"], "Technology_Description": "Global Climate Change (CC) is affecting the phenotype, abundance, and distribution of animal and plant populations as well as their interactions, e.g. phenological shifts affecting predator-prey time match-mismatch. Understanding how organisms cope with change is a fundamental objective of biologists. Scientists are now increasingly aware that ecological and evolutionary change in response to CC can occur concurrently, while their interaction can affect populations in a process called eco-evolutionary dynamics. However, we know little about the role of genetic and correlated traits variation and their relations to plasticity in the ability of organisms to cope with CC. The main goal of EcoEvoClim is to assess the role of genetic variation and plasticity in the eco-evolutionary response to CC of (mis)timed predator populations with a genetically determined colour polymorphism that covaries with behavioural traits. To this aim, I will use observational and theoretical approaches, by combining state-of-the art technology (fine-resolution GPS telemetry and bird migration radar), long-term field datasets, and latest population modelling tools (Integral Projection Models). This challenging goal will be achieved by joining a research group where world renowned experts at the forefront of developing and applying these techniques and concepts proposed here will collaborate to develop this project. EcoEvoClim, at the interface of behavioural ecology and evolutionary biology, will follow a multidisciplinary approach, synthetizing concepts from the fields of movement ecology, meteorology, remote sensing, genetics and population dynamics. The Fellowship will provide me with a unique opportunity to deepen my knowledge on eco-evolutionary research, as well as expertise in the use of modern technology for field research and analytical tools that integrate population ecology, life history theory and evolution to evaluate the likelihood of persistence of populations facing CC.", "To": ["2019-05-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-15"], "Project_ID": ["747729"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM", "UNIVERSITEIT ANTWERPEN", "UNIVERSITY OF BATH", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "UNIVERSITAT ROVIRA I VIRGILI", "STICHTING VU", "STOCKHOLMS UNIVERSITET", "Masarykova univerzita", "STIFTELSEN NORGES GEOTEKNISKE INSTITUTT", "SUEZ VYUZITI ZDROJU AS"], "EU_Contribution": ["EUR 832 500"], "Project_Title": ["Synergising International Research Studies into the Environmental Fate and Behaviour of Toxic Organic Chemicals in the Waste Stream"], "Total_Cost": ["EUR 1 008 000"], "Country": ["United Kingdom", "Belgium", "United Kingdom", "Spain", "Spain", "Netherlands", "Sweden", "Czech Republic", "Norway", "Czech Republic"], "Project_ACR": ["INTERWASTE"], "Technology_Description": "The overall vision of INTERWASTE is to develop scientific understanding of issues related to environmental contamination with toxic organic chemicals (specifically flame retardants (FRs) and pharmaceutical and personal care products (PPCPs)) arising from their presence in the waste stream. Specific research objectives include: (a) exchange of knowledge of and best practice in methods for rapid and cost-effective identification of waste items containing restricted FRs; (b) developing scientific understanding of environmental contamination due to processing of waste items containing FRs; and (c) furthering understanding of the sources of PPCPs and FRs in the sewerage system. To facilitate such research on the global level required, INTERWASTE will exchange best practice in the analytical chemistry techniques required to study FRs and PPCPs, and evaluate the measurement capability of INTERWASTE participants via an interlaboratory comparison. INTERWASTE's vision will be achieved via a co-ordinated programme of collaboration and research secondments between world-leading research groups both within and outside the EU; coupled with annual workshops to discuss the latest findings. The research programme will exploit the complementary expertise of the consortium members, and in so doing foster synergies. Cross-sectoral interaction and knowledge sharing will be achieved via the participation of beneficiaries and partner organisations from both academic and non-academic sectors. All secondments and workshops will be conducted within a framework designed to maximise the training and career development benefits to participating staff by providing them with opportunities for knowledge and skills acquisition, with a particular (but not exclusive) focus on early career researchers. INTERWASTE's research and training programme is complemented by communication activities that will both disseminate project findings to scientific stakeholders, and engage the general public.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["734522"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["STICHTING VU", "STICHTING VU"], "EU_Contribution": ["EUR 1 331 625"], "Project_Title": ["Brain meets spine: the neural origin of toddler\u2019s first steps"], "Total_Cost": ["EUR 1 331 625"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["Learn2Walk"], "Technology_Description": "A child\u2019s first steps may be small, but they are a giant leap for its development. Children have an instinct to walk from the moment they are born \u2013 a 'stepping reflex' hardwired in their neural circuitry \u2013 but it typically takes about one year before they can start walking independently. In a pioneering work published on Science in 2011, I demonstrated that the coordinated muscle activation in neonate stepping is described by two basic activation patterns that are retained throughout development, and supplemented by two new ones that be-come manifest in toddlers.", "To": ["2022-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-02-01"], "Project_ID": ["715945"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["CHARITE - UNIVERSITAETSMEDIZIN BERLIN", "CHARITE - UNIVERSITAETSMEDIZIN BERLIN"], "EU_Contribution": ["EUR 1 491 235"], "Project_Title": ["Deep imaging with time-reversed light"], "Total_Cost": ["EUR 1 491 235"], "Country": ["Germany", "Germany"], "Project_ACR": ["DeepLight"], "Technology_Description": "Microscopy enabled the birth of modern neuroscience, by allowing Ram\u00f3n y Cajal to formulate the neuron doctrine. Since then, remarkable advances in optical resolution, speed and probe development allowed scientists to study the function of neuronal circuits with ever increasing detail \u2013 with one critical limitation: No conventional microscope can focus light deeper into intact tissue than a fraction of a mm. This leaves 90% of the intact rodent brain and over 99% of the intact primate brain inaccessible. As a result, the deepest layers of the neocortex and nearly all subcortical structures are currently outside the reach of non-invasive microscopy, representing a fundamental barrier towards further progress in understanding the brain.", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["714560"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["STICHTING VU", "STICHTING VU"], "EU_Contribution": ["EUR 1 597 291"], "Project_Title": ["Proving or improving yourself: longitudinal effects of ability beliefs on neural feedback processing and school outcomes"], "Total_Cost": ["EUR 1 597 291"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["BRAINBELIEFS"], "Technology_Description": "To successfully complete secondary education, persistent learning behavior is essential. Why are some adolescents more resilient to setbacks at school than others? In addition to actual ability, students\u2019 implicit beliefs about the nature of their abilities have major impact on their motivation and achievements. Ability beliefs range from viewing abilities as \u201centities\u201d that cannot be improved much by effort (entity beliefs), to believing that they are incremental with effort and time (incremental beliefs). Importantly, ability beliefs shape which goals a student pursues at school; proving themselves (performance goals) or improving themselves (learning goals). The central aims of the proposal are to unravel 1) the underlying processing mechanisms of how beliefs and goals shape resilience to setbacks at school and 2) how to influence these mechanisms to stimulate persistent learning behavior.", "To": ["2022-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-03-01"], "Project_ID": ["716736"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["THE UNIVERSITY OF WARWICK"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Explicit Methods for the Darmon Programme"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ExplicitDarmonProg"], "Technology_Description": "Elliptic curves are the heart of contemporary research in number theory. For example, their modularity played a crucial role in Wiles' proof of Fermat's Last Theorem. Understanding their rational points is the subject of the Birch and Swinnerton-Dyer Conjecture (BSD), one of the seven $1M Clay Mathematics Institute Millennium Prizes. This proposal is concerned with rational points on elliptic curves and linked to both BSD and modularity.", "To": ["2017-08-31, Grant Agreement terminated |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["655662"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["ECOLE SUPERIEURE DE PHYSIQUE ET DECHIMIE INDUSTRIELLES DE LA VILLE DEPARIS", "FONDATION PIERRE-GILLES DE GENNES POUR LA RECHERCHE", "KUNGLIGA TEKNISKA HOEGSKOLAN", "TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY", "RTD TALOS LIMITED"], "EU_Contribution": ["EUR 3 027 637,50"], "Project_Title": ["Fabricating colloidal materials with microfluidics"], "Total_Cost": ["EUR 3 027 637,50"], "Country": ["France", "France", "Sweden", "Israel", "Cyprus"], "Project_ACR": ["Microflusa"], "Technology_Description": "In the field of colloidal science, much progress has been done on the synthesis of complex building blocks mimicking molecular structures with the hope of elaborating innovative materials. However, in the present state of the art, the rates at which these building blocks are obtained are exceedingly small. As a consequence, even though theoretically, revolutionary materials can be imagined, throughputs are far too low to approach industrial applications. We propose to unlock this bottleneck with microfluidic technology. ", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-1-2014 - FET-Open research projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-09-01"], "Project_ID": ["664823"], "Call_for_Proposal": ["H2020-FETOPEN-2014-2015-RIA"]}, -{"Partners": ["LEIBNIZ-INSTITUT FUR ASTROPHYSIK POTSDAM (AIP)", "LEIBNIZ-INSTITUT FUR ASTROPHYSIK POTSDAM (AIP)", "HITS GGMBH"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["The Impact of Cosmic Rays on Galaxy and Cluster Formation"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Germany", "Germany", "Germany"], "Project_ACR": ["CRAGSMAN"], "Technology_Description": "\"Understanding the physics of galaxy formation is arguably among the greatest problems in modern astrophysics. Recent cosmological simulations have demonstrated that \"\"feedback\"\" by star formation, supernovae and active galactic nuclei appears to be critical in obtaining realistic disk galaxies, to slow down star formation to the small observed rates, to move gas and metals out of galaxies into the intergalactic medium, and to balance radiative cooling of the low-entropy gas at the centers of galaxy clusters. This progress still has the caveat that \"\"feedback\"\" was modeled empirically and involved tuning to observed global relations, substantially weakening the predictive power of hydrodynamic simulations. More problematic, these simulations neglected cosmic rays and magnetic fields, which provide a comparable pressure support in comparison to turbulence in our Galaxy, and are known to couple dynamically and thermally to the gas. Building on our previous successes in investigating these high-energy processes, we propose a comprehensive research program for studying the impact of cosmic rays on the formation of galaxies and clusters. To this end, we will study cosmic-ray propagation in magneto-hydrodynamic turbulence and improve the modeling of the plasma physics. This will enable us to perform the first consistent magneto-hydrodynamical and cosmic-ray simulations in a cosmological framework, something that has just now become technically feasible. Through the use of an advanced numerical technique that employs a moving mesh for calculating hydrodynamics, we will achieve an unprecedented combination of accuracy, resolution and physical completeness. We complement our theoretical efforts with a focused observational program on the non-thermal emission of galaxies and clusters, taking advantage of new capabilities at radio to gamma-ray wavelengths and neutrinos. This promises important and potentially transformative changes of our understanding of galaxy formation.\"", "To": ["2021-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations"], "From": ["2016-04-01"], "Project_ID": ["646955"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["UNIVERSITAT WIEN", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "THE UNIVERSITY OF EDINBURGH", "INSTITUT JOZEF STEFAN", "FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS", "ECOLE SUPERIEURE DE PHYSIQUE ET DECHIMIE INDUSTRIELLES DE LA VILLE DEPARIS", "UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA", "UNILEVER U.K. CENTRAL RESOURCES LIMITED", "Rhodia Laboratoire du Futur"], "EU_Contribution": ["EUR 3 895 886,88"], "Project_Title": ["Hybrid Colloidal Systems with Designed Response"], "Total_Cost": ["EUR 3 895 886,88"], "Country": ["Austria", "United Kingdom", "United Kingdom", "Slovenia", "Greece", "France", "Italy", "United Kingdom", "France"], "Project_ACR": ["COLLDENSE"], "Technology_Description": "The etymology of the word colloid stems from the Greek word for glue. The systematic study of colloids (as we perceive them nowadays) is considered to have begun in the middle of the 19th century. However, the word colloid itself had been mentioned before in very different senses. The development of the physics and chemistry of colloids really took off in the 20th century. Colloids found different applications in almost every part of our lives, and it might even seem that these systems are fully understood and \u201ctamed\u201d. In reality, this is far from the case! Both fundamental understanding and a clear application strategy are required. This is most evident when it comes to the relationship between the nature and arrangement of the colloidal particles and their macroscopic response to an external field (be that shear, electric, magnetic or gravitational fields). To elucidate this relationship we unite 7 academic and 2 industrial partners and 5 associate partners to train 15 ESRs. We aim to develop the concept of COLLoids with DEsigned respoNSE, leading to our acronym: COLLDENSE. Scientific projects are divided into three main workpackeges according to the complexity of the building blocks: deformable colloids, hybrid colloids and colloidal mixtures. The subjects vary from soft repulsive colloids, magnetic colloids, soft microgel particles, telechelic star polymers to droplets with interfaces stabilised by solid particles and DNA nano-constructs. The detailed analysis of mixtures of these components, as well as of their equilibrium and nonequilibrium thermodynamics and rheology, is the other important facet of the project. In order to obtain a complete understanding of the colloidal behaviour under an external drive we employ the three main tools of the modern natural science: experiment, computer simulations and analytical theory. This complete approach will also yield a broad training experience for the young members of the network.", "To": ["2018-12-31, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["642774"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["FORSCHUNGSZENTRUM JULICH GMBH", "INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE", "BIOTECHNOLOGY AND BIOLOGICAL SCIENCES RESEARCH COUNCIL", "VIB", "CONSIGLIO NAZIONALE DELLE RICERCHE", "THE UNIVERSITY OF NOTTINGHAM", "STICHTING WAGENINGEN RESEARCH", "UNIVERSITE CATHOLIQUE DE LOUVAIN"], "EU_Contribution": ["EUR 4 000 000"], "Project_Title": ["Preparation for EMPHASIS: European Infrastructure for multi-scale Plant Phenomics and Simulation for food security in a changing climate"], "Total_Cost": ["EUR 4 000 000"], "Country": ["Germany", "France", "United Kingdom", "Belgium", "Italy", "United Kingdom", "Netherlands", "Belgium"], "Project_ACR": ["EMPHASIS-PREP"], "Technology_Description": "Sustainable food security and increasing availability of plant biomass for human nutrition and bioindustries is the key challenge for the coming decades. The analysis of crop performance with respect to structure, function, quality and interaction with the environment (\u201cphenotyping\u201d) remains the bottleneck for the exploitation of crop genetic diversity required for the enhancement of plant productivity and progress in plant breeding. This requires substantial and concerted action to develop and to increase the availability of phenotyping infrastructures. The European Strategic Forum for Research Infrastructure (ESFRI) has identified \u201cPlant Phenotyping\u201d as a priority for the European research area and EMPHASIS has been listed on the ESFRI ROADMAP as an infrastructure project to develop and implement a pan-European plant phenotyping infrastructure.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["INFRADEV-02-2016 - Preparatory Phase and support to early phase of ESFRI projects"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["739514"], "Call_for_Proposal": ["H2020-INFRADEV-2016-2"]}, -{"Partners": ["FORSCHUNGSZENTRUM JULICH GMBH", "FORSCHUNGSZENTRUM JULICH GMBH"], "EU_Contribution": ["EUR 1 482 220"], "Project_Title": ["Custom-made biosensors \u2013 Accelerating the transition to a bio-based economy"], "Total_Cost": ["EUR 1 482 220"], "Country": ["Germany", "Germany"], "Project_ACR": ["CUSTOM-SENSE"], "Technology_Description": "How will we meet the globally growing demand for pharmaceutically active compounds, nutrients and fine chemicals when crude oil resources are dwindling? For decades, biotechnologists have been engineering microorganisms to produce valuable compounds from sugar and biomass. However, a lack of knowledge regarding the host cell metabolism as well as long and laborious development times render this approach challenging to this day.", "To": ["2020-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2015-05-01"], "Project_ID": ["638718"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Liquid Exfoliation of Nanomaterials using Spinning Discs"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["LENSD"], "Technology_Description": "Two-dimensional (2D) nanomaterials have received significant attention over the past decade due to their remarkable material properties. Graphene is the most frequently studied, however a range of other 2D materials such as molybdenum disulfide and boron nitride have also demonstrated properties which will help society advance in areas from opto-electronics to sustainable energy. One of the biggest challenges currently facing 2D nanomaterials is scalable production. Current exfoliation processes are insufficient for industrial scale production due to high energy requirements, poor yield (typically < 5 wt%), introduction of material defects and low production rates (< 6 g/h). This project aims to address these process limitations. A novel liquid exfoliation approach will be investigated, using continuous flow over a spinning disc to create mono- and few-layer materials. The research activities will provide a new holistic insight into shear-induced liquid exfoliation, by experimentally and numerically examining how the fluid mechanics and multiphase transport phenomena over the spinning disc affect material characteristics at the nanoscale. The investigation involves cooperation between multiple disciplines. Experiments include the optical techniques of infrared thermography, high-speed imagery and particle image velocimetry. The researcher will receive extensive training in advanced numerical methods for simulating thin liquid films and interfacial flows at Imperial College London. Training in microscopy techniques will also be completed for the measurement of nanosheet defects and size. These research activities will assist the development of future liquid exfoliation technologies and are aligned with personalised actions to advance career development. The fellowship will broaden the researcher's technical and complimentary expertise, and facilitate inter-sectoral mobility from thermal to chemical engineering, nanotechnology and process intensification.", "To": ["2019-01-08, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-01-09"], "Project_ID": ["707340"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE UNIVERSITY OF LIVERPOOL", "EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH", "CIVIDEC INSTRUMENTATION GMBH", "COSYLAB LABORATORIJ ZA KONTROLNE SISTEME DD", "FOTON SRO", "GSI HELMHOLTZZENTRUM FUER SCHWERIONENFORSCHUNG Gmbh", "FORSCHUNGSZENTRUM JULICH GMBH", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN", "STAHL STEFAN", "THE UNIVERSITY OF MANCHESTER"], "EU_Contribution": ["EUR 3 848 975,64"], "Project_Title": ["Accelerators Validating Antimatter physics"], "Total_Cost": ["EUR 3 848 975,64"], "Country": ["United Kingdom", "Switzerland", "Austria", "Slovenia", "Czech Republic", "Germany", "Germany", "Germany", "Austria", "Germany", "United Kingdom"], "Project_ACR": ["AVA"], "Technology_Description": "Antiprotons, stored and cooled at low energies in a storage ring or at rest in traps, are highly desirable for the investigation of basic questions on fundamental interactions, the static structure of antiprotonic atoms, CPT tests by high-resolution spectroscopy on antihydrogen, as well as gravity experiments. Antimatter experiments are at the cutting edge of science. They are, however, very difficult to realize and have been limited by the performance of the only existing facility in the world, the Antiproton Decelerator (AD) at CERN. The Extra Low Energy Antiproton ring (ELENA) will be a critical upgrade to this unique facility and commissioned from summer 2016. This will significantly enhance the beam quality and enable new experiments.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["721559"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["TECHNISCHE UNIVERSITAET MUENCHEN", "TECHNISCHE UNIVERSITAET MUENCHEN", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 497 600"], "Project_Title": ["Neural processing of context-dependent innate behavior"], "Total_Cost": ["EUR 1 497 600"], "Country": ["Germany", "Germany", "Germany"], "Project_ACR": ["FlyContext"], "Technology_Description": "How do we decide what to choose? While certain cues are preferred, others are avoided. But even innate preferences and aversions must be evaluated in a context-dependent manner. These contexts are environmental cues, but also internal state. In this proposal, I will address how the nervous system integrates chemosensory information with internal state to produce appropriate behaviors. I will present a research program relying on fly genetics, behavior analysis, and in vivo physiology to characterize the neural circuits and mechanisms involved in context-dependent processing of sensory cues. Specifically, I will address how three different internal states (hunger, mating state, sickness) change the perception and processing of odors and tastes.", "To": ["2020-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2015-07-01"], "Project_ID": ["637472"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["FORSCHUNGSZENTRUM JULICH GMBH", "FORSCHUNGSZENTRUM JULICH GMBH"], "EU_Contribution": ["EUR 1 804 663"], "Project_Title": ["Proteolytic processing in plant stress signal transduction and responses to abiotic stress and pathogen attack"], "Total_Cost": ["EUR 1 804 663"], "Country": ["Germany", "Germany"], "Project_ACR": ["ProPlantStress"], "Technology_Description": "Site-specific proteolytic processing is an irreversible post-translational protein modification that generates distinct protein species with new functions, interactions and subcellular locations. In plants, proteolytic processing regulates hormonal and stress signaling leading to adaptation of metabolic pathways and is implicated in plant-pathogen interactions. Despite their importance, proteolytic processes have largely been identified serendipitously, specific cleavage sites have rarely been identified and only a few of the hundreds of proteases encoded in plant genomes (>800 in Arabidopsis) have been linked to any substrates.", "To": ["2020-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2015-06-01"], "Project_ID": ["639905"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE", "INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 2 499 144"], "Project_Title": ["The Genetics and Physiology of Growth and Size Determination"], "Total_Cost": ["EUR 2 499 144"], "Country": ["France", "France", "France"], "Project_ACR": ["VitruVius"], "Technology_Description": "Body size is an intrinsic property of living organisms that is intimately linked to the developmental program to produce fit individuals with proper proportions. Final size is the result of both genetic determinants and sophisticated mechanisms adapting size to available resources. Classical regeneration and transplantation experiments have established that different body parts grow according to autonomous programs, challenging the concept of systemic and harmonious growth. Therefore, coordination mechanisms must ensure that all parts have reached appropriate final size before animals stop growing. The main objective of this program is to tackle the mechanisms ensuring growth coordination and size determination. To tackle these questions, we propose to bring together physiology, genetics, advanced imaging and modelling approaches in an unprecedented integrated project. We will develop these approaches on the Drosophila model where we gained expertise, and will develop the vertebrate model Ambystoma mexicanum (axolotl) well adapted for limb growth and regeneration studies. Three major aims will be addressed:", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations"], "From": ["2017-01-01"], "Project_ID": ["694677"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["FORSCHUNGSZENTRUM JULICH GMBH", "FORSCHUNGSZENTRUM JULICH GMBH"], "EU_Contribution": ["EUR 1 994 879"], "Project_Title": ["Dynamical magnetic excitations with spin-orbit interaction in realistic nanostructures"], "Total_Cost": ["EUR 1 994 879"], "Country": ["Germany", "Germany"], "Project_ACR": ["Dynasore"], "Technology_Description": "Nano-spin-orbitronics is an emerging and fast growing field that aims at combining three degrees of freedom \u2212 spin, charge and spin-orbit interaction \u2212 to explore new nanotechnologies stemming from fundamental physics. New magnetic phases of matter are investigated using, in particular, atomic design to tailor beneficial physical properties down to the atomic level. Storage, transport and manipulation of magnetic information within a small set of atoms does not only require a fundamental understanding of their ground-state properties from the perspective of quantum mechanics, but crucially also their dynamical excited states. We propose to go beyond the state of the art by investigating from first-principles the dynamical properties of chiral spin textures in nanostructures from 2-dimensions to 0-dimension with these nanostructures being deposited on different substrates where spin-orbit interaction plays a major role. Understanding their response to external dynamical fields (electric/magnetic) or currents will impact on the burgeoning field of nano-spin-orbitronics. Indeed, to achieve efficient manipulation of nano-sized functional spin textures, it is imperative to exploit and understand their resonant motion, analogous to the role of ferromagnetic resonance in spintronics. A magnetic skyrmion is an example of a spin-swirling texture characterized by a topological number that will be explored. This spin state has huge potential in nanotechnologies thanks to the low spin currents needed to manipulate it. Based on time-dependent density functional theory and many-body perturbation theory, our innovative scheme will deliver a paradigm shift with respect to existing theoretical methodologies and will provide a fundamental understanding of: (i) the occurrence of chiral spin textures in reduced dimensions, (ii) their dynamical spin-excitation spectra and the coupling of the different excitation degrees of freedom and (iii) their impact on the electronic structure.", "To": ["2021-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2016-06-01"], "Project_ID": ["681405"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 2 251 026,28"], "Project_Title": ["From Chemical Bond Forces and Breakage to Macroscopic Fracture of Soft Materials"], "Total_Cost": ["EUR 2 251 026,28"], "Country": ["France", "France"], "Project_ACR": ["chemech"], "Technology_Description": "Soft materials are irreplaceable in engineering applications where large reversible deformations are needed, and in life sciences to mimic ever more closely or replace a variety of living tissues. While mechanical strength may not be essential for all applications, excessive brittleness is a strong limitation. Yet predicting if a soft material will be tough or brittle from its molecular composition or structure relies on empirical concepts due to the lack of proper tools to detect the damage occurring to the material before it breaks. Taking advantage of the recent advances in materials science and mechanochemistry, we propose a ground-breaking method to investigate the mechanisms of fracture of tough soft materials. To achieve this objective we will use a series of model materials containing a variable population of internal sacrificial bonds that break before the material fails macroscopically, and use a combination of advanced characterization techniques and molecular probes to map stress, strain, bond breakage and structure in a region ~100 \u00b5m in size ahead of the propagating crack. By using mechanoluminescent and mechanophore molecules incorporated in the model material in selected positions, confocal laser microscopy, digital image correlation and small-angle X-ray scattering we will gain an unprecedented molecular understanding of where and when bonds break as the material fails and the crack propagates, and will then be able to establish a direct relation between the architecture of soft polymer networks and their fracture energy, leading to a new molecular and multi-scale vision of macroscopic fracture of soft materials. Such advances will be invaluable to guide materials chemists to design and develop better and more finely tuned soft but tough and sometimes self-healing materials to replace living tissues (in bio engineering) and make lightweight tough and flexible parts for energy efficient transport.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2016-09-01"], "Project_ID": ["695351"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["STAFFORDSHIRE UNIVERSITY"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Digital Forensic Archaeology"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["Dig-For-Arch"], "Technology_Description": "The examination of physical evidence and the environment in which it is found remains pivotal in the investigation of crime. There has also been a greater appreciation in recent years of the role of archaeologists in forensic contexts where buried or concealed evidence exists. ", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-03-01"], "Project_ID": ["708974"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["FORSCHUNGSZENTRUM JULICH GMBH", "FORSCHUNGSZENTRUM JULICH GMBH"], "EU_Contribution": ["EUR 1 850 000"], "Project_Title": ["Simulation and Understanding of the Atmospheric Radical Budget for Regions with Large Emissions from Plants"], "Total_Cost": ["EUR 1 850 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["SARLEP"], "Technology_Description": "Atmospheric pollutants emitted by natural and anthropogenic sources influence significantly the quality of life on our planet. Their removal in the atmosphere is controlled by their reactions with photochemically produced hydroxyl radicals. Recent findings from experimental studies and quantum-chemical calculations suggest that an important part of atmospheric radical chemistry, which is directly linked to the self-cleansing ability of our atmosphere, has been overlooked. This causes considerable uncertainty in our understanding of the couplings between the biosphere, atmospheric chemistry and climate. The greatest impact of this lack of understanding has been found for regions with large emissions of organic compounds from plants in remote or rural areas.", "To": ["2021-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2016-03-01"], "Project_ID": ["681529"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["ECOLE SUPERIEURE DE PHYSIQUE ET DECHIMIE INDUSTRIELLES DE LA VILLE DEPARIS"], "EU_Contribution": ["EUR 92 538"], "Project_Title": ["Development of novel fluorinated reagents for preparation of drugs."], "Total_Cost": ["EUR 92 538"], "Country": ["France"], "Project_ACR": ["FLUNOVELTY"], "Technology_Description": "Around 20% of all modern drugs are fluorinated organic molecules. During the recent years, however, pharmaceutical companies struggle to deliver novel drugs to the market, because of the lack of innovative practical reagents and reactions towards \u201cdrug-like\u201d compounds. ", "To": ["2016-10-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-11-01"], "Project_ID": ["654260"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "FORSCHUNGSZENTRUM JULICH GMBH", "TECHNISCHE UNIVERSITEIT EINDHOVEN", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS", "TEIJIN ARAMID BV", "UNILEVER RESEARCH AND DEVELOPMENT VLAARDINGEN BV", "ASSOCIATION POUR LE DEVELOPPEMENT DE L'ENSEIGNEMENT ET DES RECHERCHES AUPRES DES UNIVERSITES, DES CENTRES DE RECHERCHE ET DES ENTREPRISES D'AQUITAINE"], "EU_Contribution": ["EUR 3 613 194,36"], "Project_Title": ["Directed Colloidal Structure at the Meso-Scale"], "Total_Cost": ["EUR 3 613 194,36"], "Country": ["United Kingdom", "Germany", "Netherlands", "France", "Greece", "Netherlands", "Netherlands", "France"], "Project_ACR": ["DiStruc"], "Technology_Description": "Fluid dispersions containing highly elongated colloidal particles form a plethora of ordered, liquid-crystalline states as well as glassy and gel-like disordered states already at very low concentrations. In spite of their remarkable properties, industrial applications of such dispersions have entered the market only relatively recently, in contrast to more conventional low-molecular-weight, liquid-crystalline fluids for which the major practical applications are in opto-electronic device technology, e.g., in displays, optical imaging and smart glass. Important potential applications of colloidal liquid crystals can be found in the manufacturing of high-performance fibres and in fast moving consumer goods, such as foods and home and personal care. ", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations"], "From": ["2015-01-01"], "Project_ID": ["641839"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["INSTITUTE OF PHYSICS OF NATIONAL ACADEMY OF SCIENCE OF UKRAINE", "UNIVERSITE DE FRANCHE-COMTE", "LATVIJAS UNIVERSITATES CIETVIELU FIZIKAS INSTITUTS", "TARTU ULIKOOL", "MATERIALS RESEARCH CENTER"], "EU_Contribution": ["EUR 202 500"], "Project_Title": ["The influence of the cell membrane asymmetry and curvature on the functioning of membrane proteins and the transport of therapeutic compounds"], "Total_Cost": ["EUR 202 500"], "Country": ["Ukraine", "France", "Latvia", "Estonia", "Ukraine"], "Project_ACR": ["assymcurv"], "Technology_Description": "Real cell membranes are essentially asymmetric and non-planar. Outer leaflets of the plasma membranes contain neutral lipids and glycolipids, while the inner leaflets host practically all anionic lipids and phosphoinositides. In addition to asymmetric composition the membranes are usually curved due to spontaneous curvature of the membrane lipids and an influence of membrane proteins and cytoskeleton. There are many cellular phenomena, which are influenced by the asymmetry and the membrane curvature such as formation of synaptic vesicles, blebs and apoptotic bodies, membrane fusion and splitting, budding of enveloped viruses, endo and exocytosis, etc.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Ukraine"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-01-01"], "Project_ID": ["690853"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["CONSIGLIO NAZIONALE DELLE RICERCHE", "SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI DI TRIESTE", "FUNDACIO INSTITUT CATALA DE NANOCIENCIA I NANOTECNOLOGIA", "FORSCHUNGSZENTRUM JULICH GMBH", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "CINECA CONSORZIO INTERUNIVERSITARIO", "BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "KUNGLIGA TEKNISKA HOEGSKOLAN", "E4 COMPUTER ENGINEERING SPA", "CLOUDWEAVERS LTD", "UNITED NATIONS EDUCATIONAL, SCIENTIFIC AND CULTURAL ORGANIZATION -UNESCO"], "EU_Contribution": ["EUR 4 068 863,75"], "Project_Title": ["Materials design at the eXascale"], "Total_Cost": ["EUR 4 068 863,75"], "Country": ["Italy", "Italy", "Spain", "Germany", "Switzerland", "Italy", "Spain", "Switzerland", "Sweden", "Italy", "United Kingdom", "France"], "Project_ACR": ["MaX"], "Technology_Description": "Materials are crucial to scientific and technological advances and industrial competitiveness, and to tackle key societal challenges - from energy and environment to health care, information and communications, manufacturing, safety and transportation.", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["EINFRA-5-2015 - Centres of Excellence for computing applications"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations"], "From": ["2015-09-01"], "Project_ID": ["676598"], "Call_for_Proposal": ["H2020-EINFRA-2015-1"]}, -{"Partners": ["EUROPEAN UNIVERSITY INSTITUTE"], "EU_Contribution": ["EUR 90 138,60"], "Project_Title": ["Optimal Taxation of Wealth"], "Total_Cost": ["EUR 90 138,60"], "Country": ["Italy"], "Project_ACR": ["Wealth-Taxation"], "Technology_Description": "There has been a growing concern in public and academia about rising wealth inequality. In his book Capital in the 21st Century, Thomas Piketty has proposed implementing a global progressive \u201cwealth tax\u201d in order to reduce wealth inequality. The book has spurred discussions on wealth inequality and made taxation of wealth a subject of current debate.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["749778"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["EUROPEAN UNIVERSITY INSTITUTE"], "EU_Contribution": ["EUR 180 277,20"], "Project_Title": ["The Age of Planning. Planning as a paradigm for policy history of post-war Europe: national cases and the European integration process (1940s-1960s)"], "Total_Cost": ["EUR 180 277,20"], "Country": ["Italy"], "Project_ACR": ["PLANAGE"], "Technology_Description": "The project aims at defining, conceptualizing and historicizing the paradigm of planning in order to analyze public policies in Western Europe at the national, transnational and supranational level between 1945 and the late 1960s. The fields of public policies covered by the project are economic planning, social planning, urban/spatial planning.", "To": ["2020-04-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-05-01"], "Project_ID": ["750887"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF SHEFFIELD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Balancing the immune response in cystic fibrosis: using zebrafish models of infection and inflammation to uncover new therapeutic approaches"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["CFZEBRA"], "Technology_Description": "Cystic fibrosis (CF) is a life-limiting disorder caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Chronic pulmonary infections accompanied by persistent neutrophil-dominated inflammation result in severe progressive lung injury and are the leading causes of morbidity and mortality of CF patients. In addition to known mucociliary defects, several lines of evidence suggest primary alterations in innate immune responses contribute to CF pathology. Currently, our understanding is limited by the lack of suitable animal models that recapitulate immune abnormalities found in CF patients. To address these unmet needs, I propose to develop zebrafish larvae as a tractable animal model to investigate the role of CFTR in regulating inflammation and infection.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["751977"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITEIT GENT", "ECOLE SUPERIEURE DE PHYSIQUE ET DECHIMIE INDUSTRIELLES DE LA VILLE DEPARIS", "TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY", "INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM", "FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG", "SINGLE QUANTUM BV", "UNIVERSITEIT UTRECHT"], "EU_Contribution": ["EUR 3 056 430,24"], "Project_Title": ["Nanophotonics by Nanocrystals, from integration to single photon operation"], "Total_Cost": ["EUR 3 056 430,24"], "Country": ["Belgium", "France", "Israel", "Belgium", "Germany", "Netherlands", "Netherlands"], "Project_ACR": ["Phonsi"], "Technology_Description": "Phonsi is a research and training program on the development of nanophotonic devices by means of colloidal nanocrystals. Working at the cross-roads of nanomaterials and nanophotonics, it brings together multinational and start-up companies with universities and research institutes around a research programme combining the synthesis and analysis of quantum dots (QDs) with the formation of QD-based nanophotonic devices for emitting and detecting light down to the single photon level. The consortium contains complementary, world-leading expertise that crosses research disciplines, attitudes and methodologies such as chemistry/physics/engineering, synthesis/analysis/simulation, lab-scale/industrial scale and scientific discoveries/research valorization. At each level, the project is driven by highly challenging and timely research goals, which are translated into well-defined, collaborative training-through-research projects. These train ESRs in different disciplines, give them the opportunity to work with high end scientific instrumentation and expose them to both academic and non-academic research environments. The research projects are complemented by a varied set of network-wide training events that rely on the active involvement of the trainees and stimulate their self-learning capabilities. Local specialist training addresses complementary skills, which trainees will put into practice by contributing to the training events and dedicated public engagement activities. The deep involvement of non-academic partners, including two recently established spin-offs, creates a vibrant research and training environment that fosters a spirit of research valorization. In this way, the program will enable Europe to train ESRs with the multidisciplinary skills in nanomaterials, nanotechnology and photonics the innovation union needs and to raise public interest in these fields of science and technology that are key to make our future way of living sustainable and comfortable.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2015-01-01"], "Project_ID": ["642656"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["IFOM FONDAZIONE ISTITUTO FIRC DI ONCOLOGIA MOLECOLARE"], "EU_Contribution": ["EUR 168 277,20"], "Project_Title": ["Regulation and reprogramming of alternative splicing in cellular transformation"], "Total_Cost": ["EUR 168 277,20"], "Country": ["Italy"], "Project_ACR": ["SPLICANCER"], "Technology_Description": "Alternative splicing (AS), by affecting nearly 90 percent of human genes, is the major contributor to protein diversity. Mutations that disrupt AS regulatory sequences are a widespread source of human diseases. Various evidences suggest that an AS reprogramming is critical in cell adaptation during cancer development. In spite of increasing interest in the potential oncogenic role of AS, little is known about the molecular mechanisms behind its deregulation during the somatic to the cancer cell transformation. ", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations"], "From": ["2017-07-01"], "Project_ID": ["752553"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ECOLE SUPERIEURE DE PHYSIQUE ET DECHIMIE INDUSTRIELLES DE LA VILLE DEPARIS"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["A microfluidic high throughput approach to helicase biophysics"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["MUTAnTS"], "Technology_Description": "We propose a novel high-throughput method to study the chemo-mechanical coupling in molecular motors using helicases, enzymes that couple ATP hydrolysis to unwinding of the double helix, as a model system. The method combines a cell-free expression system, droplet microfluidics and fluorescent assays with next generation sequencing to test large (up to millions of elements) libraries of helicase mutants for both unwinding and ATPase activity. The aim is to identify all sequence positions that, if mutated, lead to uncoupling, i.e. abolish unwinding while preserving ATPase activity. Once these positions are identified, their distribution on the enzyme sequence and structure will be analysed to obtain insight into the coupling mechanism. Notably the methodology could be applied to systems where the classical, structure-based analysis of the chemo-mechanical coupling is not possible. We will demonstrate our method on the RecQ helicase from e. coli using existing information on this system as a means of validation. Any further insight will be a demonstration of the power of our approach. When fully developed, our method will serve as a discovery tool for the interdisciplinary community working on helicases that includes medical, biological and physical sciences. It may be applied to aspects of helicase biophysics beyond the chemo-mechanical coupling, to other enzyme families and to screen for helicase inhibitors with higher throughput and lower cost when compared to robotic mictotitre-plate techniques. The proposed work will be carried out at the Griffiths Lab (ESPCI Paris) with a secondment at the Crick Institute (London). This project integrates the training in biophysics of the Experienced Researcher with the expertise of the Host Institution on high-throughput methods and the experience of the Secondment Institution on helicases. The Experienced Researcher will be trained in next generation sequencing and fluorescence-based approaches to molecular motors.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["749944"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ECOLE SUPERIEURE DE PHYSIQUE ET DECHIMIE INDUSTRIELLES DE LA VILLE DEPARIS"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Using the Evolution Machine to determine the mechanism of a novel Phage-Induced High-Cell-Density (PIHCD) phenotype"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["EvoMachine-Phage"], "Technology_Description": "Bacteriophages (phages) drive the evolution of bacteria by antagonistic coevolution and by promoting transfer of genetic material between bacteria. Phages are intimately involved in a range of biological processes from carbon cycling to the maintenance of human health. Despite their global importance the coevolution between natural phage communities and their bacterial hosts remains poorly understood. This project seeks to understand the mechanism behind a Phage-Induced High-Cell-Density (PIHCD) phenotype using a droplet-based microfluidic device termed the Evolution Machine, developed at the proposed institution (ESPCI Paris). Work Package 1 (WP1) will use the Evolution Machine to determine and characterize the phage(s) responsible for the PIHCD phenotype through coinfection with their Pseudomonas fluorescens host. WP2 will determine the mechanistic basis of the PIHCD phenotype using transcriptomics and genetic manipulation. Finally, in WP3 the long term coevolution between phage(s) and host will be investigated using the droplet-level selection capabilities of the Evolution Machine combined with comparative genomic analysis. Through this fellowship ESPCI Paris will gain from my expertise in molecular biology and bioinformatics while I will develop new skills in microbiology (phage-host coevolution and genetic manipulation) and microfluidic technology (Evolution Machine).", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["747527"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["TECHNISCHE UNIVERSITAT DARMSTADT", "TECHNISCHE UNIVERSITAT DARMSTADT"], "EU_Contribution": ["EUR 2 499 000"], "Project_Title": ["Turning the concept of magnetocaloric cooling on its head"], "Total_Cost": ["EUR 2 499 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["cool innov"], "Technology_Description": "Twenty years of research in magnetocaloric materials has failed to provide the necessary breakthrough that will lead to a commercial realisation of this technology and satisfy the urgent global need for more efficient refrigeration. We strongly believe that this is a result of looking in the wrong direction. The cool innov project will achieve this breakthrough by rethinking the whole concept of caloric cooling. We are rejecting the conventional idea of squeezing the best out of magneto-structural phase-change materials in relatively low magnetic fields, and instead we introduce a second stimulus in the form of pressure so that we can exploit, rather than avoid, the hysteresis that is inherent in these materials. The hysteresis will allow us to lock-in the magnetisation at saturation as the magnetising field is removed, so that magnetic fields persisting over a large area will no longer be required (instead, we can use a very focused field), and then demagnetise the material in a second step with an applied stress, enabling us to extract a lot more heat. In this case we only need to apply the magnetic field to a small volume of material, making it a completely new application for commercially available, high-temperature, YBCO-type, bulk superconducting permanent magnets. With the high-field, multi-stimuli approach proven, we will develop new magneto/mechanocaloric materials that match the new high-field, hysteresis-positive approach and start to fabricate novel heat-exchanger structures using additive manufacturing, so that we can combine a mechanically sound heat exchanger having a complex geometry with locally tailored, magneto/mechanocaloric properties. The success of cool innov will be game changing. We are being very ambitious in targeting a revolution in cooling technology, but if we succeed, we will have a huge impact on global energy consumption through greater efficiency, thanks to the novel energy materials that will be discovered within cool innov.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["743116"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["ALBERT-LUDWIGS-UNIVERSITAET FREIBURG", "ALBERT-LUDWIGS-UNIVERSITAET FREIBURG"], "EU_Contribution": ["EUR 2 498 750"], "Project_Title": ["Beyond the Silk Road: Economic Development, Frontier Zones and Inter-Imperiality in the Afro-Eurasian World Region, 300 BCE to 300 CE"], "Total_Cost": ["EUR 2 498 750"], "Country": ["Germany", "Germany"], "Project_ACR": ["BaSaR"], "Technology_Description": "This interdisciplinary project will show that inter-imperial zones and small to mid-size regional networks of exchange were crucial for ancient Transeurasian exchange connections. It will demonstrate the significance of exchange in imperial frontier zones emerging from political, economic, infrastructural, institutional and technological development within empires. This will lead to a new conceptual frame for analyzing inter-imperiality and the morphology of exchange networks within and across imperial zones.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["742645"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich"], "EU_Contribution": ["EUR 2 311 696"], "Project_Title": ["Nanoscale Vibrational Spectroscopy of Sensitive 2D Molecular Materials"], "Total_Cost": ["EUR 2 311 696"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["2DNanoSpec"], "Technology_Description": "I propose to investigate the nanometer scale organization of delicate 2-dimensional molecular materials using nanoscale vibrational spectroscopy. 2D structures are of great scientific and technological importance, for example as novel materials (graphene, MoS2, WS2, etc.), and in the form of biological membranes and synthetic 2D-polymers. Powerful methods for their analysis and imaging with molecular selectivity and sufficient spatial resolution, however, are lacking. Tip-enhanced Raman spectroscopy (TERS) allows label-free spectroscopic identification of molecular species, with \u224810 nm spatial resolution, and with single molecule sensitivity for strong Raman scatterers. So far, however, TERS is not being carried out in liquids, which is the natural environment for membranes, and its application to poor Raman scatterers such as components of 2D polymers, lipids, or other membrane compounds (proteins, sugars) is difficult. TERS has the potential to overcome the restrictions of other optical/spectroscopic methods to study 2D materials, namely (i) insufficient spatial resolution of diffraction-limited optical methods; (ii) the need for labelling for all methods relying on fluorescence; and (iii) the inability of some methods to work in liquids. I propose to address a number of scientific questions associated with the spatial organization, and the occurrence of defects in sensitive 2D molecular materials. The success of these studies will also rely critically on technical innovations of TERS that notably address the problem of energy dissipation. This will for the first time allow its application to study of complex, delicate 2D molecular systems without photochemical damage.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["741431"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITY OF EAST ANGLIA", "UNIVERSITY OF EAST ANGLIA"], "EU_Contribution": ["EUR 3 499 270"], "Project_Title": ["COMPASS: Climate-relevant Ocean Measurements and Processes on the Antarctic continental Shelf and Slope"], "Total_Cost": ["EUR 3 499 270"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["COMPASS"], "Technology_Description": "Processes on the Antarctic continental shelf and slope are crucially important for determining the rate of future sea level rise, setting the properties and volume of dense bottom water exported globally, and regulating the carbon cycle. Yet our ability to model and predict these processes over future decades remains rudimentary. This deficiency in understanding originates in a lack of observations in this inaccessible region. The COMPASS project seeks to rectify that by exploiting new technology - autonomous marine vehicles called gliders - to observe, quantify and elucidate processes on the continental shelf and slope of Antarctica that are important for climate.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["741120"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["ECOLE SUPERIEURE DE PHYSIQUE ET DECHIMIE INDUSTRIELLES DE LA VILLE DEPARIS"], "EU_Contribution": ["EUR 2 354 400"], "Project_Title": ["PhD Programme of Advanced Research in Interdisciplinary Science at ESPCI Paris"], "Total_Cost": ["EUR 4 708 800"], "Country": ["France"], "Project_ACR": ["UPtoPARIS"], "Technology_Description": "Loyal to its tradition in education and training on an interdisciplinary level between physics, chemistry and biology, ESPCI proposes a brand new international doctoral programme \u2013 UPtoPARIS. PhD fellows will have the opportunity to explore a unique environment comprising an elite engineer school, 9 joint research units and a new incubator on campus hosting 12 technology-driven start-ups \u2013 a recipe for a cutting-edge doctoral training in the heart of Paris.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2016 - Co-funding of regional, national and international programmes"], "Funding_scheme": ["MSCA-COFUND-DP - Doctoral programmes"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["754387"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2016"]}, -{"Partners": ["FORSCHUNGSZENTRUM JULICH GMBH", "ANTON PAAR GMBH", "ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOMATERIALES- CIC biomaGUNE", "CONSIGLIO NAZIONALE DELLE RICERCHE", "CR COMPETENCE AB", "DENSSOLUTIONS BV", "DWI LEIBNIZ-INSTITUT FUR INTERAKTIVE MATERIALIEN EV", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "EXACT LAB SRL", "FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS", "LS INSTRUMENTS AG", "LUNDS UNIVERSITET", "NANOSURF GMBH", "PAUL SCHERRER INSTITUT", "SYMO-CHEM BV", "THE UNIVERSITY OF EDINBURGH", "UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA", "UNIVERSITAET BAYREUTH", "UNIVERSITE DES SCIENCES ET TECHNOLOGIES DE LILLE - LILLE I", "UNIVERSITEIT ANTWERPEN", "UNIWERSYTET IM. ADAMA MICKIEWICZA W POZNANIU", "VISITECH INTERNATIONAL LIMITED", "WALBERT WOLFGANG"], "EU_Contribution": ["EUR 9 929 470,50"], "Project_Title": ["European infrastructure for spectroscopy, scattering and imaging of soft matteer"], "Total_Cost": ["EUR 9 929 470,50"], "Country": ["Germany", "Austria", "Spain", "Italy", "Sweden", "Netherlands", "Germany", "Switzerland", "Italy", "Greece", "Switzerland", "Sweden", "Germany", "Switzerland", "Netherlands", "United Kingdom", "Spain", "Germany", "France", "Belgium", "Poland", "United Kingdom", "Germany"], "Project_ACR": ["EUSMI"], "Technology_Description": "EUSMI will provide the community of European soft-matter researchers with an open-access infrastructure as a platform to support and extend their research, covering characterization, synthesis, and modeling. ", "To": ["2021-06-30, ongoing project"], "Meta": [""], "Topic_s": ["INFRAIA-01-2016-2017 - Integrating Activities for Advanced Communities"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-07-01"], "Project_ID": ["731019"], "Call_for_Proposal": ["H2020-INFRAIA-2016-1"]}, -{"Partners": ["TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY", "TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY"], "EU_Contribution": ["EUR 2 493 705"], "Project_Title": ["Mechanism Design for Data Science"], "Total_Cost": ["EUR 2 493 705"], "Country": ["Israel", "Israel"], "Project_ACR": ["MDDS"], "Technology_Description": "The way data science algorithms and techniques, central to the Internet and on-line media, are designed need to be revolutionized. Current designs ignore participants' strategic incentives. Our vision is the establishment of an entirely new repertoire of incentive-compatible data science algorithms and techniques, obtained through pioneering the application of game-theoretic mechanism design for data science. ", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["740435"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["CARDIFF UNIVERSITY"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Advanced Superlattice Infrared detectors for Space Applications"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ASISA"], "Technology_Description": "In space, infrared detectors are used for many applications such as Earth observation, post-launch satellite tracking, space-object surveillance or climate monitoring. According to the Planck's law, cold object detection requires a material with a longer wavelength \u03bb to address the Very LongWavelength InfraRed (VLWIR, \u03bb > 12 \u03bcm) spectral domain. The current state-of-the-art includes the Mercury-Cadmium-Telluride (HgCdTe) material. Although, the HgCdTe technology is already well established and manufactured by many European companies, it suffers from poor uniformity, stability and operability at longer wavelength due to compositional issues caused by the strong dependence of the energy bandgap with the Cadmium mole fraction. Efforts have therefore been driven to develop alternative infrared materials such as the Type-II InAs/GaSb SuperLattice (T2SL) that can theoretically outperform the HgCdTe technology. Even though, the T2SL has proven to be a successful approach in the mid-IR and long-IR, extending the cut-off wavelength to the VLWIR range is a new challenge to take up. The VLWIR-T2SL technology will be developed in the newly-established Institute for Compound Semiconductor (ICS) laboratories at Cardiff University (CU). If successful, this fellowship will produce a real breakthrough in the field of infrared detectors. The VLWIR-T2SL technology has a strong industrial potential, the candidate will thus engage European collaborators in early stage to demonstrate a focal plane array. This will lead to a reliable route to commercialise devices through the newly-funded Compound Semiconductor Centre. This fellowship will leverage the large investments by the Welsh and UK government and CU in the general area of compound semiconductor. The candidate will have the managerial and technical support from Prof. Diana Huffaker, as well as staff members of ICS and the School of Physics and Astronomy.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["743521"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ECOLE SUPERIEURE DE PHYSIQUE ET DECHIMIE INDUSTRIELLES DE LA VILLE DEPARIS", "ECOLE SUPERIEURE DE PHYSIQUE ET DECHIMIE INDUSTRIELLES DE LA VILLE DEPARIS"], "EU_Contribution": ["EUR 1 656 250"], "Project_Title": ["Strongly Correlated Physics and Materials for Energy Technology"], "Total_Cost": ["EUR 1 656 250"], "Country": ["France", "France"], "Project_ACR": ["StrongCoPhy4Energy"], "Technology_Description": "\"Materials where conduction electrons experience strong correlation in their dynamics, are both a challenge to the current quantum theories of matter and a mine for possible technological applications. High-temperature copper- and iron-based superconductors and heavy-fermions with large thermoelectric responses are examples of materials with high potential impact on energy transmission and storage technologies or high-magnetic field applications. ", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["724177"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["FUNDACIO PRIVADA INSTITUT CATALA D'INVESTIGACIO QUIMICA", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "UNIVERSITEIT LEIDEN", "FUNDACION IMDEA NANOCIENCIA", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "TECHNISCHE UNIVERSITAET WIEN", "UNIVERSITAT JAUME I DE CASTELLON", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "TECHNISCHE UNIVERSITAT DARMSTADT", "FORSCHUNGSZENTRUM JULICH GMBH", "UNIVERSITE DE MONTPELLIER", "CONSORZIO INTERUNIVERSITARIO NAZIONALE PER LA SCIENZA E TECNOLOGIA DEI MATERIALI", "COVESTRO DEUTSCHLAND AG"], "EU_Contribution": ["EUR 7 980 861,25"], "Project_Title": ["An Artificial Leaf: a photo-electro-catalytic cell from earth-abundant materials for sustainable solar production of CO2-based chemicals and fuels"], "Total_Cost": ["EUR 7 980 861,25"], "Country": ["Spain", "Switzerland", "Netherlands", "Spain", "Switzerland", "Austria", "Spain", "United Kingdom", "Germany", "Germany", "France", "Italy", "Germany"], "Project_ACR": ["A-LEAF"], "Technology_Description": "A novel concept for a photo-electro-catalytic (PEC) cell able to directly convert water and CO2 into fuels and chemicals (CO2 reduction) and oxygen (water oxidation) using exclusively solar energy will be designed, built, validated, and optimized. The cell will be constructed from cheap multifunction photo-electrodes able to transform sun irradiation into an electrochemical potential difference (expected efficiency > 12%); ultra-thin layers and nanoparticles of metal or metal oxide catalysts for both half-cell reactions (expected efficiency > 90%); and stateof- the-art membrane technology for gas/liquid/products separation to match a theoretical target solar to fuels efficiency above 10%. All parts will be assembled to maximize performance in pH > 7 solution and moderate temperatures (50-80 \u00baC) as to take advantage of the high stability and favorable kinetics of constituent materials in these conditions. Achieving this goal we will improve the state-of-the-art of all components for the sake of cell integration:", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["FETPROACT-01-2016 - FET Proactive: emerging themes and communities"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["732840"], "Call_for_Proposal": ["FETPROACT-2016"]}, -{"Partners": ["UNIVERSITEIT GENT", "UNIVERSITEIT GENT", "MUSEE ROYAL DE L'AFRIQUE CENTRALE"], "EU_Contribution": ["EUR 1 997 500"], "Project_Title": ["The First Bantu Speakers South of the Rainforest: A Cross-Disciplinary Approach to Human Migration, Language Spread, Climate Change and Early Farming in Late Holocene Central Africa"], "Total_Cost": ["EUR 1 997 500"], "Country": ["Belgium", "Belgium", "Belgium"], "Project_ACR": ["BantuFirst"], "Technology_Description": "The Bantu Expansion is not only the main linguistic, cultural and demographic process in Late Holocene Africa. It is also one of the most controversial issues in African History that still has political repercussions today. It has sparked debate across the disciplines and far beyond Africanist circles in an attempt to understand how the young Bantu language family (ca. 5000 years) could spread over large parts of Central, Eastern and Southern Africa. This massive dispersal is commonly seen as the result of a single migratory macro-event driven by agriculture, but many questions about the movement and subsistence of ancestral Bantu speakers are still open. They can only be answered through real interdisciplinary collaboration. This project will unite researchers with outstanding expertise in African archaeology, archaeobotany and historical linguistics to form a unique cross-disciplinary team that will shed new light on the first Bantu-speaking village communities south of the rainforest. Fieldwork is planned in parts of the Democratic Republic of Congo, the Republic of Congo and Angola that are terra incognita for archaeologists to determine the timing, location and archaeological signature of the earliest villagers and to establish how they interacted with autochthonous hunter-gatherers. Special attention will be paid to archaeobotanical and palaeoenvironmental data to get an idea of their subsistence, diet and habitat. Historical linguistics will be pushed beyond the boundaries of vocabulary-based phylogenetics and open new pathways in lexical reconstruction, especially regarding subsistence and land use of early Bantu speakers. Through interuniversity collaboration archaeozoological, palaeoenvironmental and genetic data and phylogenetic modelling will be brought into the cross-disciplinary approach to acquire a new holistic view on the interconnections between human migration, language spread, climate change and early farming in Late Holocene Central Africa.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["724275"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITAET HAMBURG", "UNIVERSITAET HAMBURG"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Suspended Fluidic nanochannels as optomechanical sensors for single molecules"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["FLUINEMS"], "Technology_Description": "Early detection of cancer saves lives: the survival rate increases from 10% to 90%. Today, there is a lack of methods for the early detection of different types of cancer. The main challenge is that a large variety of specific biomarkers have to be counted, and usually at extremely low concentrations. ", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["714073"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["THE QUEEN'S UNIVERSITY OF BELFAST", "FOLKEHELSEINSTITUTTET", "THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN", "NORGES MILJO-OG BIOVITENSKAPLIGE UNIVERSITET", "INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE", "Universidad Austral de Chile", "VETERINAERINSTITUTTET - NORWEGIAN VETERINARY INSTITUTE", "UNIVERSITE DE LIEGE", "BioDetection Systems B.V.", "PROTOQSAR 2000 SL"], "EU_Contribution": ["EUR 3 974 594,76"], "Project_Title": ["PROTECTion against Endocrine Disruptors;Detection, mixtures, health effects, risk assessment and communication."], "Total_Cost": ["EUR 3 974 594,76"], "Country": ["United Kingdom", "Norway", "United Kingdom", "Norway", "France", "Chile", "Norway", "Belgium", "Netherlands", "Spain"], "Project_ACR": ["PROTECTED"], "Technology_Description": "PROTECTED aims to develop expertise and protective capabilities against Endocrine Disruptors (EDs). EDs and their mixtures are a modern day health concern leading to failing ecological systems, poor agricultural production and health effects such as obesity, cancer and infertility. While analytical methods have advanced enormously, focus has been mainly on synthetic chemicals, overlooking emerging EDs and real-life multiple substance exposure. A new generation of creative, entrepreneurial and innovative early-stage researchers equipped with skills to assess and understand the real-life risk of complex mixtures of EDs and trained to convert resulting knowledge and ideas into accessible tools and services for the long-term control of potential ED risk is urgently needed. The PROTECTED Innovative Training Network [ITN] proposes a holistic approach by providing 15 individual, personalised research projects with exposure to scientific, innovative and entrepreneurial training mobility across the ITN. The intersectorial network is comprised of 12 training sites at academia, research centres, a bioassay technology SME, a QSAR technology SME, water provider, and animal feed supplier. Together they cover multiple disciplines including analytical science of food, feed, and environment, epidemiology, risk assessment, social science and toxicology. This combined expertise enables a highly focused program for developing novel tools and concepts and training for the detection, analysis and improved risk assessment of EDs, especially mixture effects. Methodology will include emerging technologies; multiplexed analysis, mixture modelling, mechanistic and exposure studies, explants and cell or whole organism bioassays. The project will provide a unique and high level of training for a new generation of specialists with transferable skills and enhanced career perspectives. These specialists will ultimately aid the efficient development of future control strategies for improved health.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["722634"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["UNIVERSITEIT GENT", "UNIVERSITEIT GENT"], "EU_Contribution": ["EUR 2 499 500"], "Project_Title": ["Load Slice Core: A Power and Cost-Efficient Microarchitecture for the Future"], "Total_Cost": ["EUR 2 499 500"], "Country": ["Belgium", "Belgium"], "Project_ACR": ["Load Slice Core"], "Technology_Description": "The ideal processor building block is a power and cost-efficient core that can maximize the extraction of memory hierarchy parallelism, a combination that neither traditional in-order nor out-of-order cores provide. We propose the Load Slice Core microarchitecture, a restricted out-of-order engine aimed squarely at extracting memory hierarchy parallelism, which, according to preliminary results, delivers a nearly 8 times higher performance per Watt per euro compared to an out-of-order core. ", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["741097"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 2 430 140"], "Project_Title": ["Large-Scale Formal Proof for the Working Mathematician"], "Total_Cost": ["EUR 2 430 140"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["ALEXANDRIA"], "Technology_Description": "Mathematical proofs have always been prone to error. Today, proofs can be hundreds of pages long and combine results from many specialisms, making them almost impossible to check. One solution is to deploy modern verification technology. Interactive theorem provers have demonstrated their potential as vehicles for formalising mathematics through achievements such as the verification of the Kepler Conjecture. Proofs done using such tools reach a high standard of correctness.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["742178"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITEIT GENT"], "EU_Contribution": ["EUR 172 800"], "Project_Title": ["Development and application of NMR-based tools to inorganic nanocarriers for effective vaccine delivery"], "Total_Cost": ["EUR 172 800"], "Country": ["Belgium"], "Project_ACR": ["NMR4Nanos"], "Technology_Description": "There is an urgent need for new vaccines, but avoiding side effects is crucial for patient compliance. To address this, new generation vaccines with safe, but weakly immunogenic antigens are formulated with carriers and adjuvants to induce the desired immunological response. Inorganic nanoparticles (NP) have shown potential as carriers while immune stimulators of microbial origin are proven to ensure long lasting immune response. Their successful integration into nanovaccines requires thorough analysis of the inorganic/organic interface. Solution state NMR spectroscopy has recently been established as a potent characterisation tool towards this end. ", "To": ["2019-09-03, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-04"], "Project_ID": ["703374"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["MEDICAL RESEARCH COUNCIL"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Structural role of protein splicing factors in promoting an active configuration of the spliceosome's RNA catalytic core"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SpliceosomeStructure"], "Technology_Description": "The spliceosome is a ribonucleoprotein machine that excises introns from pre-messenger RNAs. During my phD, I identified RNA ligands for the magnesium ions that catalyze these splicing reactions and showed that the spliceosomal U6 and U2 small nuclear RNAs form a structure resembling group II self-splicing intron RNAs. Although the spliceosome's catalytic core is RNA-based, numerous spliceosomal proteins promote the proper catalytic fold of this RNA core, juxtapose the reactive pre-mRNA elements with the U6 metal sites, and regulate spliceosome dynamics during the splicing cycle. Indeed, the Prp8 protein cross-links with the critical nucleotides of the catalytic RNA core and its crystal structure, reported recently by the host laboratory, revealed a cavity that accommodates the catalytic RNA core. Moreover, several helicases, such as Brr2 and Prp16, promote an active configuration of the U2/U6 RNA core and associated proteins and regulate their dynamics. The arrangement of such proteins in the assembled spliceosome and their interactions with the RNA core is presently unknown due to the lack of high-resolution structures of any spliceosomal complexes. I will study biochemically in vitro the interactions between the U2/U6 core and key proteins necessary for an active fold of the RNA core, with the goal of reconstituting and solving the high-resolution structure of a minimal active U2/U6 RNA core in complex with the reactive pre-mRNA sites and surrounding proteins including Prp8. In parallel, I will employ recent advances in cryo-electron microscopy sample preparation, imaging, and data processing, which were pioneered at the host institute, to obtain high-resolution (at least 7 Angstroms) three-dimensional reconstructions of endogenous fully assembled spliceosomes stalled at specific splicing stages. These studies promise to provide unprecedented structural insihgt into the configuration and dynamics of key RNA and protein elements of the spliceosome.", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations"], "From": ["2016-03-01"], "Project_ID": ["657492"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITE GRENOBLE ALPES", "UNIVERSITE GRENOBLE ALPES"], "EU_Contribution": ["EUR 2 434 742,51"], "Project_Title": ["Seismic Functional Imaging of the Brittle Crust"], "Total_Cost": ["EUR 2 434 742,51"], "Country": ["France", "France"], "Project_ACR": ["F-IMAGE"], "Technology_Description": "Despite the dramatic impact of earthquakes, the physics of their onset and the short-term behavior of fault are still poorly understood. Using existing high quality seismic observations, we propose to develop a novel functional imaging of the brittle crust to clarify not only structural properties but also the dynamics of faults. We will analyze spatio-temporal changes of elastic properties around fault zones to highlight the interplay between changes in the host rocks and fault slip. Imaging the damage structure around faults and its evolution requires new seismological methods. With novel methods to image the highly heterogeneous fault regions, we will provide multi-scale descriptions of fault zones, including their laterally variable thicknesses and depth dependence. In parallel we will image temporal changes of seismic velocities and scattering strength. External natural forcing terms (e.g. tides, seasonal hydrologic loadings) will be modeled to isolate the signals of tectonic origin. This will also allow us to monitor the evolving seismic susceptibility, i.e. a measure of the proximity to a critical state of failure. Improved earthquake detection techniques using \u2018deep machine learning\u2019 methods will facilitate tracking the evolution of rock damage. The imaging and monitoring will provide time-lapse images of elastic moduli, susceptibility and seismicity. The observed short-time changes of the materials will be included in slip initiation models coupling the weakening of both the friction and the damaged host rocks. Laboratory experiments will shed light on the transition of behavior from granular (shallow fault core) to cohesive (distant host rock) materials. Our initial data cover two well-studied fault regions of high earthquake probability (Southern California and the Marmara region, Turkey) and an area of induced seismicity (Groningen). The derived results and new versatile imaging and monitoring techniques can have fundamental social and economic impacts.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["742335"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["WEIZMANN INSTITUTE OF SCIENCE", "WEIZMANN INSTITUTE OF SCIENCE"], "EU_Contribution": ["EUR 2 220 000"], "Project_Title": ["Delineation of molecular mechanisms underlying the establishment and breakdown of immunological tolerance in the thymus"], "Total_Cost": ["EUR 2 220 000"], "Country": ["Israel", "Israel"], "Project_ACR": ["ThymusTolerance"], "Technology_Description": "Central tolerance is shaped in the thymus, a primary lymphoid organ, where immature T lymphocytes are \u201ceducated\u201d into mature cells, capable of recognizing foreign antigens, while tolerating the body\u2019s own components. This process is driven mainly by two separate lineages of thymic epithelial cells (TECs), the cortical (cTEC) and the medullary (mTEC). While cTECs are critical at the early stages of T cell development, mTECs play a pivotal role in negative selection of self-reactive thymocytes and the generation of Foxp3+ regulatory T (Treg) cells. Crucial to the key role of mTECs in the screening of self-reactive T cell clones, is their unique capacity to promiscuously express and present almost all self-antigens, including thousands of tissue-specific antigen (TSA) genes. Strikingly, the expression of most of this TSA repertoire in mTECs is regulated by a single transcriptional regulator called Aire. Indeed, Aire deficiency in mice and human patients results to multi-organ autoimmunity. Although there has been dramatic progress in our understanding of how thymic epithelial cells shape and govern the establishment of adaptive immunity and of immunological self-tolerance, there are still several outstanding questions with no comprehensive answers. Therefore, in the research proposed herein, we wish to provide more comprehensive answers to these still elusive, but very fundamental questions. Specifically we will aim at: 1.) Delineation of molecular mechanisms controlling TEC development and thymus organogenesis; 2.) Delineation of molecular mechanisms underlying promiscuous gene expression in the thymus; 3.) Identification and characterization of molecular determinants responsible for the breakdown of thymus-dependent self-tolerance. To this end, we will build upon our recently published data, as well as unpublished preliminary data and utilize several state-of-the-art and interdisciplinary approaches, which have become an integral part of our lab\u2019s toolbox.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["724821"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["THE UNIVERSITY OF EDINBURGH", "THE UNIVERSITY OF EDINBURGH"], "EU_Contribution": ["EUR 1 893 626"], "Project_Title": ["Honour in classical Greece: esteem, status, identity, and society in ancient Greek literature, life, and thought"], "Total_Cost": ["EUR 1 893 626"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["HCG"], "Technology_Description": "If \u2018honour\u2019 is an outmoded term, its modern analogues \u2013 esteem, respect, recognition, dignity, status, prestige, deference, face, image, etc. \u2013 still shape the dynamics of human social interaction. But modern understandings of honour in the societies and literatures of the past \u2013 especially the literature of ancient Greece \u2013 tend to present it as a single, specific, and more or less monolithic notion especially associated with zero-sum competition between alpha-males, a notion that is typically superseded by more co-operative, inclusive, and egalitarian values, whether in fifth-century BC Athenian democracy or in the eighteenth-century AD enlightenment. Where honour survives in popular perception as a characteristic of modern communities it is typically ghettoized in the world of inner-city gangs, in the Muslim East, or in the traditional machismo of the Mediterranean.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["741084"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["MEDICAL RESEARCH COUNCIL"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Controlled cryo-EM sample preparation through DNA-Origami pillars"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["EM-Pillars"], "Technology_Description": "Electron cryomicroscopy (cryo-EM) is rapidly emerging as a powerful technique for high-resolution structure determination of protein complexes. Despite recent advances, there is still ample room for improvement of this method, in particular regarding sample preparation. Outstanding challenges are reproducibility of freezing conditions to obtain an optimal ice thickness; to prevent unfolding or preferential orientation of proteins against the hydrophobic air-water interface; and a limited accuracy of beam-induced motion correction for relatively small particles. Here, we propose to study how DNA origami objects that are added in with the sample may affect cryo-EM grid preparation. In addition, by examining a variety of DNA origami structures in the electron microscope, we also aim to identify and improve on structural weaknesses in their design. We will test new design strategies, analyse those, and use them for application in cryo-EM. Thereby, this proposal will facilitate both cryo-EM structure determination and the design of nano-tools that are made from DNA.", "To": ["2017-07-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations"], "From": ["2015-08-01"], "Project_ID": ["657990"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["AALTO-KORKEAKOULUSAATIO"], "EU_Contribution": ["EUR 191 325,60"], "Project_Title": ["Multisensory-Based Spatial Sound"], "Total_Cost": ["EUR 191 325,60"], "Country": ["Finland"], "Project_ACR": ["MULTISSOUND"], "Technology_Description": "The worlds of multisensory research and multimedia technologies have originated and, for the most part, still remain largely independent. The first exists mostly within the field of experimental psychology, or psychophysics, while the second one is mostly studied and developed by engineers. This project aims at implementing this perfect multidisciplinary marriage in the field of acoustics. A series of psychophysical experiments will be carried out at Aalto School of Engineering, in the Spatial Sound Group, aiming at obtaining detailed guidelines on how to reproduce sound for the best audiovisual experience. The results will be further applied to a new sound spatialization algorithm designed specifically to enhance human audiovisual experience, while reducing computational complexity where it is not needed. The ultimate goal is to reach every consumer, namely in television, cinema, gaming, computer streaming and teleconferencing applications. Direct actions to reach the general community, as well as the industry, will ensure maximum practical impact. ", "To": ["2017-10-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-11-01"], "Project_ID": ["659114"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["AALBORG UNIVERSITET"], "EU_Contribution": ["EUR 200 194,80"], "Project_Title": ["Mooring of floating wave energy converters:numerical simulation and uncertainty quantification"], "Total_Cost": ["EUR 200 194,80"], "Country": ["Denmark"], "Project_ACR": ["MoWE"], "Technology_Description": "This project aims at designing mooring system for floating wave energy converters (WECs) using a design approach based on numerical uncertainty quantification to estimate loads to a given tolerance level. This approach is to be compared to traditional deterministic approach with safety factors in terms of cost of the designed system. This is to be achieved by: (i) using an uncertainty quantification (UQ) toolbox based on general polynomial chaos (gPC) into a state-of-the-art mooring dynamics solver; (ii) to perform detailed numerical investigation on the influence on snap-loads on the mooring design. All parts aim at providing a base for lowering the economic cost of the mooring system.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["752031"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN", "LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN"], "EU_Contribution": ["EUR 2 486 375"], "Project_Title": ["The Chemical Basis of RNA Epigenetics"], "Total_Cost": ["EUR 2 486 375"], "Country": ["Germany", "Germany"], "Project_ACR": ["EPiR"], "Technology_Description": "The genetic code consists of a defined sequence of four canonical nucleosides and the sequence of these bases carries the blueprints of all life on earth. It is apparent that this sequence information alone is not sufficient to explain how a multicellular organism can establish specialized cells like the 200 known cells types of a human body. For this, a second information layer is required and since a few years, it is apparent that this information layer is strongly based on Chemistry. Histones, DNA and RNA are the target of sophisticated chemical modification, which establishes a second layer of information. This proposal aims at decoding this chemical code on RNA, specifically on messenger RNA. More than 150 chemical derivatives of RNA nucleosides are known and many more await discovery. We are proposing a program to study RNA modifications and to decipher their function. We are expecting to answer key questions about the structures, the distribution and the biological function of numerous known and yet unknown chemical RNA derivatives that brings us deep into unexplored areas of science. Since some of the modified bases equip RNA with yet unknown reactivity we will study the functional aspects of reactive bases, which allows us to tackle some of the most important questions associated with the RNA world theory. Our results will move Europe into a central position in the new field of RNA epigenetics, which has the potential to become the next big wave in science 63 years after the discovery of the double helix structure. We are perfectly positioned to move the field forward. We established quantitative methods to study modified bases that uncovered a new biological principles in cancer cells (Carell, Carmeliet, Lamberts Nature 2016) and we contributed to the RNA world theory (Carell Science 2016). We applied proteomic tools to learn about the function of new DNA bases that we partially even discovered (Carell, Vermeulen Cell 2013; Carell Nat. Chem. Biol. 2014).", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["741912"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Mechanisms of stress-induced cognitive deficits : Role of the glucocorticoid receptor and its partners in the regulation of PFC function."], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["StressPFCog"], "Technology_Description": "The prefrontal cortex (PFC) is a locus for higher-order cognition and executive control across species. In most mental disorders such as depression or schizophrenia, dysfunction in PFC and its related neuronal networks has been associated with a variety of cognitive impairments. Chronic stress exposure and abnormal levels of glucocorticoid stress hormone (GCs) is a key environmental risk factor for psychiatric illness. The PFC is highly vulnerable to stress exposure and many studies have reported detrimental effects of chronic stress exposure and/or high GCs levels on cognition, however the physiological underpinnings remain poorly understood. GCs exert their action in part by binding the glucocorticoid receptor (GR), a transcription factor expressed in every cell type. Through a complex interplay with co-factors, GR can modulate the expression of a large set of genes and thereby modify brain circuit physiology ultimately leading to behavioural changes. In this project, I propose to investigate the molecular and cellular mechanisms through which stress-exposure can modify the activity of PFC and its related networks and lead to cognitive impairment. ", "To": ["2020-01-03, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2018-01-04"], "Project_ID": ["753296"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Minimal Model for Pox-Virus Infection"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["MMXVI"], "Technology_Description": "Viral diseases represent one of the world\u2019s highest socio-economic burdens. Increased global trade and travel, climate change resulting in shifting viral vectors, and the emergence of new and often deadly viruses is inevitable. Therefore, detailed understanding of the complexity of virus particles and the development of new model systems to study them, will be essential to develop new research, diagnostic, and therapeutic tools. The structural changes that occur during the initial contact between a virus and its host remains one of the major challenges in infection biology. Until recently, the investigation of viral nano-architecture and dynamic changes that occur in virus particles during the infectious lifecycle was limited to methods, such as EM, with no capacity to capture dynamic events or define molecular specificity. The goal of the proposed project is to create a new minimal model of virus infection based on cell-derived membrane blebs. The model will be amenable to novel super-resolution microscopy (SRM) methods that allow the visualization of viral structures at resolutions of tens of nanometers. Recently developed analytical tools like single-virion averaging allows the generation of precise models from hundreds of events. This affords unprecedented insights into the biological and biophysical requirements of virus infection. Furthermore, we aim to investigate the dynamics of virus architectural changes during the first stages of infection, particularly at the membrane level, by combining single-molecule techniques with our new model-system. While initially aimed at investigating protein structure-function relationships within the prototypic poxvirus, vaccinia, the model system and imaging developments outlined will be broadly applicable to a wide range of biological systems including other viruses. Thereby, this proposal looks to advance the field of infection biology into the nanoscale.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["750673"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["BOURNEMOUTH UNIVERSITY"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Predicting adaptive responses of protected species to environmental changes to optimise conservation management frameworks in Europe"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ADAPTATION"], "Technology_Description": "Environmental changes, including habitat loss and climate change, are negatively impacting biodiversity at global levels, with accelerating extinction rates of species. Whilst the EU Biodiversity Strategy aims to halt and then reverse these losses of species, data on the conservation status of many protected species is lacking, inhibiting their management. Effective conservation is reliant on robust data on protected species, yet there is a substantial knowledge gap between traditional monitoring methods that record abundances and conservation management frameworks that require the integration of species\u2019 ecology with their adaptive responses to rapidly changing environments. The primary aim of this Fellowship is to thus deliver a novel conservation management framework for a model protected species, integrating ecological and genetic data, to provide a new predictive basis for European conservation management programmes. The sea lamprey Petromyson marinus is the model species, a protected species on Annex II of the EU Habitats Directive that provides multiple generations for testing the effects of environmental change on candidate genes. Research objectives quantify P. marinus European genetic diversity and structure, test for the presence of novel genetic mutations across populations, identify the genetic regions associated with adaptation to specific environmental parameters and develop an eco-evolutionary model of P. marinus population dynamics as the basis for its conservation management framework. As the project delivers highly innovative genetic and ecological research, it brings together a leading European researcher with high genetic knowledge with a European research group with exceptional expertise in conservation ecology. Together, their knowledge transfer and training activities will deliver novel conservation tools supporting European conservation strategies and launch a new research agenda in biodiversity and conservation management.", "To": ["2018-11-13, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-11-14"], "Project_ID": ["705615"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["OXFORD BROOKES UNIVERSITY"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Innovative learning platform for knowledge integration in Energy Retrofit"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["C-mapER"], "Technology_Description": "This proposal revolves around two specific questions: 1) to what extent multidisciplinary strategies to improve energy performance of existing buildings and neighbourhoods can be integrated; and 2) how this integration can bring technology and sustainable redevelopment of existing buildings together. It aims to develop an innovative learning platform for Knowledge Integration in Energy Retrofit (C-mapER) to develop the skills to manage complexity inherent in retrofit projects. An alternative method and an associated platform to evaluate and manage complexity, through a novel application of meaningful learning activities in designing technological solutions for energy retrofit, is the main vehicle.The objectives are to: 1) develop a conceptual framework of the key concepts and relationships that influence Energy Retrofit projects in workpackage 1 (WP1), 2) develop the beta version of the platform (WP2); and 3) test, refine, verify and disseminate the platform (WP3).The ultimate goal is to revolutionalise the traditional approach to educating future professionals, which is currently based on rote learning. ", "To": ["2019-09-17, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-18"], "Project_ID": ["751376"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Logic-based Attribution and Forensics in Cyber Security"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["AF-Cyber"], "Technology_Description": "Recent studies states that \"Devices will continue to grow in volume and variety, and the forecast for connected devices by 2020 is 200 billion and climbing\". The increase of connectivity brings a drastic impact on the increase of cyber attacks. Protecting measurements are not enough, while finding who did the attack is a crucial for preventing the escalation of cyber attacks.", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["746667"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Quantum control of levitated nanoparticles"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["QUCLN"], "Technology_Description": "Coherent control of a macroscopic quantum system is one of the main objectives of the field of optomechanics with potentially game changing implications for fundamental physics as well as technology. On one side it could allow the exploration of the classical-to-quantum boundary, on the other it could allow the development of quantum limited sensors and provide a fundamental building block for quantum information. ", "To": ["2019-05-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-15"], "Project_ID": ["749709"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Scattering Matrix Approach in Reflection applied to Turbid media"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["SMART"], "Technology_Description": "This project aims to (1) demonstrate innovative optical imaging by increasing by 2x the depth penetration of optical coherence tomography (OCT) and (2) make groundbreaking advances in the study of 3D Anderson localization (AL) of light. These seemingly different topics are in fact closely linked. Wave transport in complex media can be described by the Green\u2019s matrix (GM), which holds complete information about propagation between every input and output point of the medium. The need to understand and work with the GM underpins the proposed work of this action. Recently, the field GM for light was measured for the first time using a white-light illumination, opening up new avenues for fundamental and applied physics. This action will combine this approach with matrix methods (previously applied to ultrasound imaging) to build a \u2018SMART-OCT\u2019 apparatus: an innovative OCT-like system based on a matrix approach that enables the acquisition of the GM and elimination of multiple scattering. SMART-OCT will have 2x the current OCT depth limit (>2 mm) with no loss in resolution or affordability (white light illumination). The SMART-OCT system will be tested on biological tissues, compared to current OCT, and patented and developed towards market. Like all technology, the creation of this device will be accompanied by advances in fundamental science. The optical field GM will be used to study AL of light \u2013 the \u2018trapping\u2019 of waves due to interference effects induced by strong disorder. This concept is important for light control and confinement, but past experiments in optics have always suffered from absorption and non-linearities. The proposed method can sidestep these issues to give the first unambiguous study of 3D AL for light. The execution of these projects in parallel will develop the sensitivity and range of SMART-OCT.", "To": ["2019-08-17, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2017-08-18"], "Project_ID": ["744840"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF LEICESTER"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Restoration of motor dysfunction in vivo through nanomaterials based devices"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["NanoZfish"], "Technology_Description": "Spinal cord injury (SCI) and amyotrophic lateral sclerosis (ALS) are nervous system maladies that impair the function of spinal central pattern generators for locomotion. These disorders carry a significant social and economic burden, owing to a lack of effective therapeutic treatments. In the field of nanotechnology, carbon nanotubes (CNT) have shown outstanding promise for the improvement of neuronal function in vitro and are thus ideal candidates for repairing or ameliorating spinal defects associated with these disorders. The ultimate goal of this project is to develop CNT as a tool for restoring motor dysfunctions associated with SCI and ALS. Specifically, I will use zebrafish larvae as an in vivo model for testing the therapeutic efficacy of this innovative class of implantable devices. I will implant CNT and graphene based devices in healthy, spinal cord lesioned and ALS zebrafish models and test their effects on spinal cord function with a range of powerful in vivo techniques. My project will address three specific aims. First, biocompatibility of implanted devices will be assessed using in vivo patch clamping of spinal motoneurons in healthy fish implanted with nanodevices. Second, I will implant CNT into fish that have been subjected to SCI. Nanomaterial-facilitated functional recovery will then be tested with in vivo patch clamping of spinal motor neurons, analysis of locomotor behaviour and confocal microscopy. Finally, I will use similar approaches to determine if implanted CNT can slow or reverse spinal cord defects in a SOD1 mutant zebrafish model of ALS. The project will advance our knowledge in an innovative field of bioscience research and help to inform the development of alternative approaches to the treatment of SCI and ALS. Embedded in an international environment, such as that of the University of Leicester, I will support my research activity through a greater level of independence, with the aim of publishing papers as senior author.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["747167"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ANGLIA RUSKIN UNIVERSITY HIGHER EDUCATION CORPORATION"], "EU_Contribution": ["EUR 97 727,40"], "Project_Title": ["Default meanings in compound interpretation"], "Total_Cost": ["EUR 97 727,40"], "Country": ["United Kingdom"], "Project_ACR": ["Demeco"], "Technology_Description": "Languages always change, and existing words are constantly combined into novel combinations such as \u2018trout pout\u2019 or \u2018bucket list\u2019. Surprisingly, little is known about the actual processes and resources humans use to understand these novel combinations. This project will investigate a central question in the field of linguistics, namely the extent to which people rely on inherent meanings of words in combination (lexical semantics), compared with the extent to which they infer meaning from context (pragmatics). The interdisciplinary nature of the project is strong. It will use a combination of psycholinguistic techniques, with big data from corpus linguistics to empirically test hypotheses derived from state-of-the-art accounts in theoretical linguistics. Firstly, a questionnaire study will establish the extent to which people vary in their interpretation of different noun-noun combinations, and what determines the degree of variation. The study will innovatively use a large semantically annotated dataset to generate representative experimental items. Secondly, advanced eye-tracking technology will be used to investigate how these combinations fare when presented in contexts that either support or do not support a dominant interpretation. Together, the results of the two studies will shed light on the balance of word meaning and context in the interpretation of new combinations and either confirm or refute the underlying assumptions of competing semantic theories. The results will be of benefit in applications such as the automatic processing and translation of human language, and the assessment of misleading language usage, e.g. in advertising. They will also benefit theoretical linguists and psycholinguists, by showing how insights from each area can fruitfully be applied to the other. For the researcher, the project offers an invaluable opportunity to train in cutting-edge empirical techniques and gain skills in public engagement and research communication.", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["752436"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ALBERT-LUDWIGS-UNIVERSITAET FREIBURG", "ALBERT-LUDWIGS-UNIVERSITAET FREIBURG"], "EU_Contribution": ["EUR 149 981"], "Project_Title": ["Hide and Seek with Cancer Drugs"], "Total_Cost": ["EUR 149 981"], "Country": ["Germany", "Germany"], "Project_ACR": ["DeShield"], "Technology_Description": "Cancer is one of the most prominent causes for morbidity and mortality in industrialized countries. The key challenge in drug-based anti-cancer therapy is to efficiently kill the cancer cells while minimizing side-effects on healthy parts of the body. The DeShield project will establish the proof of concept for a novel approach to upgrade existing anti-cancer drugs in a way that the anti-cancer effect will be increased while side-effects will simultaneously minimized. DeShield technology will be used to shield approved anti-cancer drugs while circulating in the body in order to minimize side effects. Once the shielded drug accumulated at the cancer site, an external stimulus will be applied to trigger de-shielding. The drug will then locally and specifically be taken up by the cancer cells to exert its therapeutic effect. We have successfully demonstrated the functionality of the DeShield technology using the clinically approved anti-cancer drug Doxil and human cancer cell lines: when the shield is intact, the drug is not taken up by the cells, only upon inducible un-shielding the drug enters and kills the cells. In the DeShield project we aim at establishing the Proof-of-Concept that this approach is functional in cancer animal models, that it increases the therapeutic effect while minimizing side-effects. To this aim we have assembled a team with high expertise in complementary areas covering the technology itself, the conductance of preclinical animal studies up to clinical trials as well as business expertise. The technical advance obtained in this project together with a comprehensive market research and the development of a business strategy will shape a highly attractive commercial proposition for the successful valorization of our ERC-funded research.", "To": ["2018-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["755369"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich"], "EU_Contribution": ["EUR 2 500 000"], "Project_Title": ["Mass, heat and spin transport in interlinked quantum gases"], "Total_Cost": ["EUR 2 500 000"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["TransQ"], "Technology_Description": "The objective of the proposed project is to create a versatile experimental and methodological platform for exploring transport mechanisms with quantum gases. Our approach will enable studying the dynamics of mass, heat and spin transport between linked reservoirs with a unique degree of control and flexibility, and promises to open up a route to discovering yet-unknown transport phenomena.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["742579"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["AALTO-KORKEAKOULUSAATIO", "AALTO-KORKEAKOULUSAATIO"], "EU_Contribution": ["EUR 2 418 002"], "Project_Title": ["Superconducting quantum heat engines and refrigerators"], "Total_Cost": ["EUR 2 418 002"], "Country": ["Finland", "Finland"], "Project_ACR": ["SQH"], "Technology_Description": "The aim of the proposed work is to realize experimentally the first genuinely quantum mechanical refrigerator/heat engine in the solid state, and test whether one can boost its performance by information/feedback, optimized control, and merely by exploiting the quantum coherences vs the classical dynamics. To achieve this goal, we will investigate experimentally and theoretically the thermodynamics of open quantum systems. For the experimental realization, we will develop calorimetry with superior energy and time resolution and build competitive quantum circuits based on superconducting quantum bits (qubits). In order to achieve the ultimate goal, we will, for the first time, implement a test for quantum fluctuation relations in a truly open quantum system, and demonstrate an implementation of the so-called quantum Maxwell's Demon by controlling a qubit in an optimal way. In our studies we will utilize the state-of-the-art nanofabrication and measurement facilities of the national OtaNano research infrastructure that I coordinate.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["742559"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 3 487 580"], "Project_Title": ["Magnetic Fields and the Formation of New Worlds"], "Total_Cost": ["EUR 3 487 580"], "Country": ["France", "France"], "Project_ACR": ["NewWorlds"], "Technology_Description": "Magnetic fields impact the formation of low-mass stars and their planets, and contribute to setting adequate conditions for life to appear. They control the amount of material and angular momentum from which stars and their planets form and mature, and can save newborn close-in planets from falling into their host stars. Magnetic fields can also affect planets by eroding their atmospheres and limiting their habitability, while hampering at the same time their detectability. Our understanding of these issues is however limited and critically needs observational guidance.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-10-01"], "Project_ID": ["740651"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["HELSINGIN YLIOPISTO", "HELSINGIN YLIOPISTO"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Informatics approaches for the rational selection of personalized cancer drug combinations"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Finland", "Finland"], "Project_ACR": ["DrugComb"], "Technology_Description": "Making cancer treatment more personalized and effective is one of the grand challenges in our health care system. However, many drugs have entered clinical trials but so far showed limited efficacy or induced rapid development of resistance. We critically need multi-targeted drug combinations, which shall selectively inhibit the cancer cells and block the emergence of drug resistance. This project will develop mathematical and computational tools to identify drug combinations that can be used to provide personalized and more effective therapeutic strategies that may prevent acquired resistance. Utilizing molecular profiling and pharmacological screening data from patient-derived leukaemia and ovarian cancer samples, I will develop model-based clustering methods for identification of patient subgroups that are differentially responsive to first-line chemotherapy. For patients resistant to chemotherapy, I will develop network modelling approaches to predict the most potential drug combinations by understanding the underlying drug target interactions. The drug combination prediction will be made for each patient and will be validated using a preclinical drug testing platform on patient samples. I will explore the drug combination screen data to identify significant synergy at the therapeutically relevant doses. The drug combination hits will be mapped into signalling networks to infer their mechanisms. Drug combinations with selective efficacy in individual patient samples or in sample subgroups will be further translated into in treatment options by clinical collaborators. This will lead to novel and personalized strategies to treat cancer patients.", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["716063"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 240 318"], "Project_Title": ["Structure-performance relationships in porous carbons for energy storage"], "Total_Cost": ["EUR 1 240 318"], "Country": ["France", "France"], "Project_ACR": ["SuPERPORES"], "Technology_Description": "Supercapacitors are of great interest as energy storage systems because they exhibit very high rates of charge/discharge, long cycle lifes, and they are made of cheap and light materials. These attractive properties arise from the electrostatic nature of the charge storage which results from ion adsorption in the electrode pores. Recently, it was demonstrated that ions can enter pores of sub-nanometer sizes leading to a huge increase of capacitance. This was an important breakthrough as the energy density of supercapacitors, relatively low compared to batteries, is what currently limits their application. ", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-07-01"], "Project_ID": ["714581"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["DOUGLAS CONNECT GMBH", "JOHANNES GUTENBERG-UNIVERSITAT MAINZ", "FUNDACIO CENTRE DE REGULACIO GENOMICA", "UNIVERSITEIT MAASTRICHT", "THE UNIVERSITY OF BIRMINGHAM", "NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.", "UPPSALA UNIVERSITET", "MEDIZINISCHE UNIVERSITAT INNSBRUCK", "INFORMATICS MATTERS LIMITED", "INSTITUT NATIONAL DE L ENVIRONNEMENT ET DES RISQUES INERIS", "STICHTING VU"], "EU_Contribution": ["EUR 2 999 112,50"], "Project_Title": ["OpenRiskNet: Open e-Infrastructure to Support Data Sharing, Knowledge Integration and in silico Analysis and Modelling in Risk Assessment"], "Total_Cost": ["EUR 2 999 112,50"], "Country": ["Switzerland", "Germany", "Spain", "Netherlands", "United Kingdom", "Greece", "Germany", "Sweden", "Austria", "United Kingdom", "France", "Netherlands"], "Project_ACR": ["OpenRiskNet"], "Technology_Description": "Toxicology and risk assessment are undergoing a paradigm shift, from a phenomenological to a mechanistic discipline based on in vitro and in silico approaches that represent an important alternative to classical animal testing applied to the evaluation of chronic and systemic toxicity risks. Large databases and highly sophisticated methods, algorithms and tools are available for different tasks such as hazard prediction, toxicokinetics, and in vitro \u2013 in vivo extrapolations to support this transition. However, since these services are developed independently and provided by different groups world-wide, there is no standardized way how to access the data or run modelling workflows. To overcome the fragmentation of data and tools, OpenRiskNet will provide open e-Infrastructure resources and services to a variety of communities requiring chemical risk assessment, including chemicals, cosmetic ingredients, therapeutic agents, and nanomaterials. OpenRiskNet will combine the achievements from earlier projects for generating modeling and validation workflows, knowledge integration and data management as well as include all ongoing projects and important stakeholders through an associated partner programme. The main components of the infrastructure will be an interoperability layer added to every service to describe the functionality and guaranteeing technical and semantic interoperability, a discovery service, deployment options based on container technology, and packaging of the infrastructure into virtual instances. This will be complemented by training and support on integration of specific services based on prototype implementation, usage of standard file formats for data sharing including the generation of templates for data and metadata, as well as the harmonized usage of ontologies. Case studies will demonstrate the applicability of the infrastructure in productive settings supporting research and innovation in safer product design and risk assessment.", "To": ["2019-11-30, ongoing project"], "Meta": [""], "Topic_s": ["EINFRA-22-2016 - User-driven e-infrastructure innovation"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Switzerland"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2016-12-01"], "Project_ID": ["731075"], "Call_for_Proposal": ["H2020-EINFRA-2016-1"]}, -{"Partners": ["INSTITUT CURIE", "INSTITUT CURIE"], "EU_Contribution": ["EUR 1 498 750"], "Project_Title": ["Characterisation of DNA Double-Strand Break Repair by Alternative End-Joining: Potential Targets for Cancer Therapy"], "Total_Cost": ["EUR 1 498 750"], "Country": ["France", "France"], "Project_ACR": ["altEJrepair"], "Technology_Description": "DNA repair pathways evolved as an intricate network that senses DNA damage and resolves it in order to minimise genetic lesions and thus preventing tumour formation. Gaining in recognition the last few years, the alternative end-joining (alt-EJ) DNA repair pathway was recently shown to be up-regulated and required for cancer cell viability in the absence of homologous recombination-mediated repair (HR). Despite this integral role, the alt-EJ repair pathway remains poorly characterised in humans. As such, its molecular composition, regulation and crosstalk with HR and other repair pathways remain elusive. Additionally, the contribution of the alt-EJ pathway to tumour progression as well as the identification of a mutational signature associated with the use of alt-EJ has not yet been investigated. Moreover, the clinical relevance of developing small-molecule inhibitors targeting players in the alt-EJ pathway, such as the polymerase Pol Theta (Pol\u03b8), is of importance as current anticancer drug treatments have shown limited effectiveness in achieving cancer remission in patients with HR-deficient (HRD) tumours.", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-07-01"], "Project_ID": ["714162"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["STICHTING VU", "EVERCYTE GMBH", "UNIVERSITE D'ARTOIS", "UNIVERSITE DE LAUSANNE", "BIOTALENTUM TUDASFEJLESZTO KFT", "KATHOLIEKE UNIVERSITEIT LEUVEN", "Department of Health", "Newcells Biotech Limited", "ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI", "LIVERPOOL JOHN MOORES UNIVERSITY", "KEMIJSKI INSTITUT", "UNIVERSITEIT UTRECHT", "DOUGLAS CONNECT GMBH", "MEDIZINISCHE UNIVERSITAT INNSBRUCK"], "EU_Contribution": ["EUR 3 860 843,40"], "Project_Title": ["An integrated interdisciplinary approach to animal-free chemical and nanomaterial safety assessment"], "Total_Cost": ["EUR 3 860 843,40"], "Country": ["Netherlands", "Austria", "France", "Switzerland", "Hungary", "Belgium", "United Kingdom", "United Kingdom", "Italy", "United Kingdom", "Slovenia", "Netherlands", "Switzerland", "Austria"], "Project_ACR": ["in3"], "Technology_Description": "All chemicals whether they are drugs, cosmetics, agrochemicals or others need to be tested for their safety to man and the environment. The use of whole animal studies for the prediction of adverse effects in man, is problematic due to species dependent effects, high costs and a large burden to animals in terms of numbers and suffering. While there have been major improvements in human in vitro and in silico techniques, there is still a lack of an integrated risk assessment platform. The in3 proposal aims to significantly further the development of animal-free chemical and nanomaterial (NM) safety evaluation by creating a scientific and training program aimed at integrating human in vitro testing with computational approaches. The project will focus on human induced pluripotent stem cells (hiPSC) derived tissues, including liver, kidney, brain, lung and vasculature and to utilise mechanistic toxicology, quantitative adverse outcome pathways, biokinetics, cheminformatics and modelling approaches to derive testable prediction models. hiPSC present the major advantages provide non-cancerous derived tissues with identical genetic backgrounds. All Early Stage Researchers (ESRs) will work towards the same goal, utilising the same chemicals, donor cells, assays and software packages. All data will be centrally housed in standardised formats, appropriately annotated and linked with protocols and material information. While ESRs will hone their skills in their own field of expertise, they will also collaborate to create an in depth safety evaluation testing platform for the chosen test compounds. By interaction, problem solving, training and secondments over the three years, they will acquire a unique set of interdisciplinary skills for chemical and NM safety assessment. The project aims to accelerate the realisation of animal-free safety assessment and to graduate 15 PhD students with the ideal skill sets to carry out the strategy designed in in3 in the near future.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["721975"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["UNIVERSITY OF DURHAM"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Inside the Mind of Ancient People: the tangible and constructed landscape of the western Delta in the Late Period (664-332BC)"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["MAP"], "Technology_Description": "MAP aims to generate an experimental and innovative methodology combining the \u201csociology of space\u201d critical theory and the archaeological (material and textual) evidence offered by ancient Egyptian society, in order to examine the constitution of space as product of social action or social structures, and recursively to identify the points of contact where the landscape shaped and changed the mind of people. Ancient Egyptian temple libraries preserve a number of written records which provide insights into the religious and geographic knowledge. The challenge is not to harmonize written and archeological sources inside a monadic dimension but to measure the differences, as a way to discover multiple and conflicting stories from the human mind and the actions imposed onto the physical/mental landscape. The \u201cregionally specific sacerdotal\u201d officials during the Late Period (664-332 BC) in the western Delta of Egypt (2nd-7th provinces of Lower Egypt) is adopted as the research-program case-study, on account of its exceptional significance for archaeology, written sources and lack of any substantive previous research programs. MAP represents an innovative theoretical and methodological contribution for understanding the interaction between physical geography and the intimate conception/perception of the physical space inside the geography of ancient Egypt. The goals of MAP will be achieved adopting an intradisciplinary methodology, aimed to reconnect archaeology and philology, through: 1) analysis of the \u201cregionally specific sacerdotal\u201d officials inside written and artifactual sources; 2) landscape archaeology in order to provide a plot map of the physical environment, through which human entities moved and operated; 3) a comparative dimension aimed to generate a theoretical model, which will open new horizons on how humans and the environment interacted, how the environment changed in the mental process and how the mental process was entangled in a tangible geography.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["744977"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Bio-INspired GOld metamaterials"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["BINGO"], "Technology_Description": "The development of metamaterials has opened new opportunities for designing novel devices in the field of imaging, data storage and sensing. Although some progress has been achieved in in this emerging area, the fabrication of nanoscale metamaterials with tailorable geometries still remains challenging. This proposal aims to develop a facile and scalable synthesis approach to gold metamaterials inspired by nature. The key novelty of the action is to use self-assembled cellulose nanocrystals as templates to fabricate gold morphologies with chiral periodic organization. The goals of the action are (I) the isolation of cellulose nanocrystals from bulk celluloses and their co-assembly to highly organized CNC and CNC/Au chiral scaffolds, (II) the post-treatment of such chiral films to achieve high porosity and excellent compatibility with gold precursors, (III) the development of a facile wet-chemical route to continuous gold morphologies exploiting the self-assembly of cellulose nanocrystals, (VI) the optical characterization of CNC-templated gold structures. The cellulose-assisted synthesis of gold metamaterials has a potential to open a new pathway for fabrication of novel metamaterials and potentially can become a breakthrough technique in metamaterial engineering.", "To": ["2019-02-28, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-03-01"], "Project_ID": ["743543"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KAROLINSKA INSTITUTET", "KAROLINSKA INSTITUTET"], "EU_Contribution": ["EUR 1 923 262,50"], "Project_Title": ["Cellular Position Tracking Using DNA Origami Barcodes"], "Total_Cost": ["EUR 1 923 262,50"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["CellTrack"], "Technology_Description": "The research I propose here will provide an enabling technology; spatially resolved transcriptomics, to address important problems in cell- and developmental-biology, in particular: How are stem cells in the skin and gut proliferating without turning into cancers? How are differentiated cells related, in their transcriptome and spatial positions, to their progenitors?", "To": ["2022-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["724872"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["LUNDS UNIVERSITET"], "EU_Contribution": ["EUR 173 857,20"], "Project_Title": ["Fiscal capacity and warfare in Europe and Latin America in the long nineteenth century (1789-1913)."], "Total_Cost": ["EUR 173 857,20"], "Country": ["Sweden"], "Project_ACR": ["WARCAP"], "Technology_Description": "This project seeks to contribute to understanding the impact of warfare on the expansion of fiscal capacity in the long nineteenth century (1789-1913) in Europe and Latin America. The relationship between late-modern warfare and fiscal institutions has been a contested issue. Even though wars may exert a negative short-time impact on public revenues due to the physical destruction that they cause, several authors have suggested that over the long run they may promote fiscal innovations that improve the government\u2019s capacity to collect taxes. However, our knowledge about state-making and the rise of fiscal capacity in late modern times is still insufficient. To begin with, much more emphasis should be placed in the effects exerted by limited and civil wars. Unlike mass warfare, limited and civil wars do not necessarily trigger the social and political changes associated to permanent increases of public revenues. Secondly, the interaction between warfare and economic and political factors still remains open to question. ", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["752163"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF LEEDS"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["The Bacteroides dual-pumping membrane-integral pyrophosphatase: a novel drug target"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["BactoDrug"], "Technology_Description": "Membrane-integral pyrophosphatases (M-PPases) couple cleavage of pyrophosphatase to pumping of ions across a membrane to generate membrane potential and play an important role in resistance to stressors. The solved structures of an H+-pumping M-PPase from Vigna radiata and an Na+-pumping M-PPase from Thermotoga maritima show M-PPases form a channel through the membrane, and this channel is plugged by an ion gate formed by three charged residues. Despite these structures, there are still many outstanding questions regarding M-PPases, especially in relation to H+ and Na+ dual-pumping M-PPases.", "To": ["2017-05-31, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-06-01"], "Project_ID": ["659677"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM", "UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 2 444 446"], "Project_Title": ["Dynamics of Probed, Pulsed, Quenched and Driven Integrable Quantum Systems"], "Total_Cost": ["EUR 2 444 446"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["DYNAMINT"], "Technology_Description": "This proposal intends to develop and apply a new-generation theoretical toolbox for understanding the rich dynamics of strongly-interacting many-body quantum sytems subjected to destabilizing manipulations bringing them very far from equilibrium. ", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["743032"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["RIJKSUNIVERSITEIT GRONINGEN", "RIJKSUNIVERSITEIT GRONINGEN"], "EU_Contribution": ["EUR 2 499 974,51"], "Project_Title": ["Systems Chemistry: Steps Towards De-Novo Life"], "Total_Cost": ["EUR 2 499 974,51"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["ToDL"], "Technology_Description": "Can we synthesise life de-novo in the lab? This is one of the Grand Challenges of contemporary Science. Overall objective of this project is to set important steps in turning chemistry into biology by building fully synthetic chemical systems that contain and integrate some of the essential elements of life: replication, metabolism and compartmentalisation. Functional coupling of any of life\u2019s essential elements has not been achieved, at least not without making use of biomolecules. We now aim to achieve such coupling and develop fully chemical systems to become increasingly life-like. Specific aims are:", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["741774"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["FCIENCIAS.ID - ASSOCIACAO PARA A INVESTIGACAO E DESENVOLVIMENTO DE CIENCIAS", "FCIENCIAS.ID - ASSOCIACAO PARA A INVESTIGACAO E DESENVOLVIMENTO DE CIENCIAS"], "EU_Contribution": ["EUR 1 231 319"], "Project_Title": ["The Medieval and Early Modern Nautical Chart: Birth, Evolution and Use"], "Total_Cost": ["EUR 1 231 319"], "Country": ["Portugal", "Portugal"], "Project_ACR": ["MEDEA-CHART"], "Technology_Description": "Of all the technical and scientific developments that made possible the early modern maritime expansion, the nautical chart is perhaps the least studied and understood. This fact is very surprising as it was through those charts that the newly discovered world was first shown to the amazed eyes of the European nations. Although the History of Cartography is a well-established academic discipline and old charts have been examined for many years, their detailed technical study is still in its infancy. What is the origin of the pre-Mercator nautical chart, how charts evolved technically over time and how they were used at sea are all critical questions that remain to be answered. I intend to approach these challenges in a truly interdisciplinary way, by using innovative and powerful tools as a complement to the traditional methods of historical research: analytical cartometric methods, numerical modelling and the examination of the manuscripts through special lighting. By applying these tools to a large sample of charts of various periods and origins, I aim to unveil hidden graphic content related to their construction and use, to characterize their main geometric features, to establish meaningful connections with contemporary navigational methods and exploration missions, and to numerically simulate their construction by taking into account the explanations given in the textual sources. The effectiveness of those techniques has already been demonstrated in my previous studies, such as in the solution of an historical enigma which had been alive for more than a century: the construction of the Mercator projection, in 1569. Now, I propose to handle a broader and more complex set of questions, which has eluded the historians of cartography for even a longer period. The clarification of these issues will have a ground-breaking impact, not only in the strict field of the History of Cartography, but also in the context of the intellectual history at large.", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Portugal"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-06-01"], "Project_ID": ["714033"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["UNIVERSITAT WIEN"], "EU_Contribution": ["EUR 166 156,80"], "Project_Title": ["Development of Maximum Efficiency Phase Contrast Electron Microscopy"], "Total_Cost": ["EUR 166 156,80"], "Country": ["Austria"], "Project_ACR": ["DIGIPHASE"], "Technology_Description": "Electron microscopy is a key technique for imaging and analysis of materials. Although aberration correction has made atomic resolution possible at low accelerating voltages, beam damage remains a critical limitation for many types of materials. The imaging modes currently in use today are inefficient in terms of the number of transmitted electrons detected and the way in which these are used to derive information. Current detectors integrate over details in the angular distribution of scattered intensities, and make use of only a limited range of scattering angles. In the case of scanning transmission electron microscopy (STEM), a wealth of information is contained in the distribution of electron scattering as a function of the illuminating probe position. The proposed work will make use of pixelated detectors to record this four-dimensional data set and develop methods to intelligently utilize the information it contains. This research project has become possible through recent advances in the sensitivity and speed of pixelated detectors, and offers a new path to maximize the information gained per fast electron. Maximum efficiency phase contrast imaging in STEM recovers the full amplitude and phase components of the specimen, with minimum dose, and maximum signal to noise ratio, and maximum contrast that does not require aberrations. In materials science for example it will enable imaging of charge transfer at point defects and interfaces while simultaneous Z-contrast imaging provides interpretability and chemical sensitivity. Similarly, such high sensitivity phase detection will allow the direct imaging of local electric and magnetic fields at the highest possible spatial resolutions, providing many new opportunities for understanding electronic, spintronic and magnetic materials at the heart of today\u2019s technological advances. In biology, maximum efficiency phase contrast imaging may open the door to the ultimate low dose molecular- and bio-imaging.", "To": ["2017-06-30, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-07-01"], "Project_ID": ["655760"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["FUNDACIO INSTITUT DE CIENCIES FOTONIQUES"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Exploring Photon-photon Interactions with Cold Rydberg Atoms"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["EPICA"], "Technology_Description": "\"The requirements for the basic building blocks of Quantum Information Processing (QIP) are sometimes contradictory: one must seek components that are immune to interactions to preserve their fragile quantum properties, and, at the same time, to have strong, controllable interactions to perform operations on the quantum information they carry.", "To": ["2017-08-31, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2015-09-01"], "Project_ID": ["658258"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["The dynamics and rheology of self-assembled empty liquids: from patchy toy models to anisotropic realistic systems"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["DELTAS"], "Technology_Description": "In this project I plan to investigate by means of numerical simulations the dynamics and rheology of low-density equilibrium gels made of limited-valence building blocks. I will start with simple toy models of patchy particles and then add complexity in the form of inner degrees of freedom by investigating systems that undergo a hierarchical self-assembly process. Examples of such systems are recently synthesised DNA constructs and telechelic star polymers. The novelty of DELTAS lies in the focus put on the role of the internal flexibility as a tool to tune the dynamics and the rheology of equilibrium gels. Indeed, the possibility of fine-tuning the structure of these materials lend themselves well to many applications, ranging from medicine to material science. The project goes one step further by proposing to investigate the kinetics, dynamics and mechanical properties of these systems in the framework of (flexible) patchy systems. The usage of simple toy models will grant a better understanding of the phenomenology of these systems. In addition, the realistic systems I plan to investigate will, on one hand, establish a stronger link between theory and numerical simulations and experiments and, on the other hand, provide a testing ground for the results obtained with toy models.", "To": ["2018-03-31, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-04-01"], "Project_ID": ["702298"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN", "THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN"], "EU_Contribution": ["EUR 148 619"], "Project_Title": ["Plants as sensors for standardization and calibration of controlled environment chambers"], "Total_Cost": ["EUR 148 619"], "Country": ["Ireland", "Ireland"], "Project_ACR": ["PlantSenseKit"], "Technology_Description": "Research in plant biology & crop breeding conducted in controlled environment chambers (CECs) require that observed differences in measured plant traits between or within CECs are attributable to the imposed experimental treatment or breeding protocol rather than to heterogeneity and/or poor accuracy in the monitoring of different chamber environmental conditions. To date, no commercial product has been developed which tests standardization of environmental conditions within and between CECs of the same manufacturer or between different manufacturers. The cost per chamber of deploying a full artificial sensor network to test for homogeneity of CEC conditions would be thousands of euros per CEC; a prohibitive cost for users and manufacturers alike. This Proof of Concept grant will develop and commercialize the first plant-based sensor kit for standardization and calibration of CECs used in plant research, commercial horticulture and by the international plant breeding sector (BAYER Crop Science, MONSANTO etc.) at one tenth of the cost of an artificial sensor network and with equal or better environmental sensing capacity. Commercialization of PlantSenseKit will be via a license agreement to a commercial partner and involve comprehensive market research, competitor analysis, and further technological refinement of the PlantSenseKit protocol, prototype testing & development of a business plan. This Proof of Concept grant will have a positive impact on society and economic activities by improving the performance of infrastructure used in food security and climate change research and by providing new jobs for Ireland via commercialization of PlantSenseKit.", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["727578"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["VILNIAUS UNIVERSITETAS"], "EU_Contribution": ["EUR 130 779,60"], "Project_Title": ["High throughput screening of single-cells using droplet microfluidics"], "Total_Cost": ["EUR 130 779,60"], "Country": ["Lithuania"], "Project_ACR": ["Cells-in-drops"], "Technology_Description": "Tackling heterogeneous cell populations at single-cell resolution is becoming increasingly important in different branches of biology and biomedicine. Many useful techniques have been developed to profile and even selectively purify single-cells, however, the demand for techniques with better analytical performance and improved high-throughput capabilities, remains very high. Droplet microfluidics can fulfill this demand by bringing higher throughput, scalability and single molecule resolution that are hard to achieve with conventional technologies. In this project, a droplet microfluidics platform will be developed and applied for ultra-high-throughput single-cell screening and sequencing. The project will be focused on B-cells that produce therapeutic antibodies or biomolecules of industrial interest. Cell compartmentalization into microfluidic droplets together with capture beads and barcoded DNA primers will enable a direct establishment of the linkage between the genotype (genes or mRNA) and phenotype (binding, regulatory or activity of secreted proteins). The proposed work will allow the quantitative high-throughput antibody phenotyping without loosing the original heavy-light chain pairing, a significant advantage over other technologies. Like no other system available to-date this the technological approach outlined in this proposal will provide a unique way to identify the primary sequence of heavy and light IgG genes encoding functional monoclonal antibodies directly from single-cells, without a need to perform gene cloning or cell immortalization. The results of this work are likely to bring a significant impact not only in applied biological sciences but also in biotechnology and biomedicine.", "To": ["2018-03-20, Grant Agreement terminated |"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Lithuania"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-03-21"], "Project_ID": ["705791"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Scanning probe energy loss spectroscopy of Nanoscale Alloy Particles for heterogeneous CATalysis"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SNAPCAT"], "Technology_Description": "Most heterogeneous catalysts take the form of catalytically active nanoparticles dispersed over a support medium. To improve catalytic function and reduce waste, researchers are increasingly seeking to improve the homogeneity of these nanoparticles, whether it be their size, shape or composition. One of the difficulties facing researchers is that the techniques used to obtain quantitative information are typically averaged over ensembles of billions of nanoparticles. Measurements of individual clusters require access to expensive instrumentation such as a scanning transmission electron microscope (STEM). The proposed research will apply scanning probe energy loss spectroscopy (SPELS) to study the composition, size and shape of individual size-selected Pt-based binary alloy nanoparticles for fuel cell applications, deposited using an inert gas-aggregation source. In SPELS, a STM tip is used as a highly localised source of field-emitted electrons to stimulate surface excitations such as plasmons. The energy of inelastically backscattered electrons from the surface is analysed with a spectrometer, so that spectroscopic mapping of the surface can be obtained as the tip is rastered across the surface. This comparatively low-cost method is capable of producing a spatial resolution of 1-10 nm, so that the composition of individual nanoparticles can be sampled. SPELS will be used, in conjunction with STM, to study the composition and surface structure of bimetallic clusters before and after reaction. This data will be correlated with data on the reactivity of the clusters, probed by CO temperature programmed desorption measurements. These measurements will be used to tailor nanoparticle composition and improve homogeneity, resulting in more efficient catalysts.", "To": ["2018-04-30, Grant Agreement terminated |"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["703864"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITY OF GLASGOW"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["The role of amphidial drug uptake in the mode of action and resistance to ivermectin in nematodes of livestock"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["IDRAM"], "Technology_Description": "The macrocyclic lactones such as ivermectin are the cornerstone for the treatment of key nematode infections of livestock, crops and man. Resistance to many of these broad-spectrum anthelmintics is becoming commonplace, while new classes of active compounds are increasingly difficult to find, threatening food supplies and public heatlh worldwide. The exact molecular and biochemical mechanisms of resistance, particularly to the widely used macrocyclic lactone class, are still poorly understood, impeding the development of efficient strategies to control drug resistance. I hypothesize that the amphidial sensory organs of nematodes are the major route of macrocyclic lactone drug uptake and that mutations in this uptake mechanism represents the primary source of drug resistance. In the first phase of the project, I will develop laboratory methods for testing amphid function in two parasitic nematodes of veterinary significance, the trichostrongyles Haemonchus contortus and Teladorsagia circumcincta. These techniques will be applied on drug resistant and sensitive isolates to evaluate the role of amphids in ivermectin uptake. In the second phase, I will use the C. elegans model to generate mutants resistant to three major classes of anthelmintic drugs, ivermectin, the benzimidazole albendazole and the imidazothiazole levamisole. I will then apply genomic tools to identify alleles responsible of this multi-drug resistance phenotype. This project aims to understand the link between amphid defects, anthelmintic drug uptake, and development of resistance, and will generate a thorough knowledge of this unexplored and apparently widespread resistance mechanism in nematodes. These results will also pave the way to the implementation of a fast and reliable measurement of drug resistance in the field. On the whole, the project will bring a direct contribution to current veterinary and public health challenges by suggesting new strategies to limit the emergence of drug resistance.", "To": ["2019-08-31, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["747676"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ERASMUS UNIVERSITEIT ROTTERDAM"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["Monetary Spaces and hierarchies in Europe. Impact of Complementary Currencies"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["MICCO"], "Technology_Description": "This research seeks to measure and analyse the social and economic impact of selected Community Currencies in Europe with the use of a self-assessment Total Quality Management model called Common Assessment Framework. Complementary Currencies (CC) are a type of money designed to circulate alongside the Central Bank\u2019s money to address objectives that the conventional money system does not. CC are tied to a specific demarcated community (i.e. locality, mutual-credit networks, sectoral vouchers). The Common Assessment Framework (CAF) engages the organisation and its beneficiaries and performs a study of its structure and operation at a particular point in time and place.", "To": ["2018-08-31, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["704759"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "POTSDAM INSTITUT FUER KLIMAFOLGENFORSCHUNG", "JOHANNES GUTENBERG-UNIVERSITAT MAINZ", "RUHR-UNIVERSITAET BOCHUM", "UNIVERSITY OF WAIKATO"], "EU_Contribution": ["EUR 144 000"], "Project_Title": ["QUantitative paleoEnvironments from SpeleoThems"], "Total_Cost": ["EUR 229 500"], "Country": ["United Kingdom", "Germany", "Germany", "Germany", "New Zealand"], "Project_ACR": ["QUEST"], "Technology_Description": "Speleothems (cave deposits, e.g. stalagmites) represent unique terrestrial archives that allow for accurately dated, high-resolution (often annual), continuous and long (many millennia) climate reconstructions. Such records are vital for understanding how climate varies and how our environments respond on seasonal to millennial timescales. However, current speleothem studies can only make qualitative inferences about climate parameters \u2013 i.e. they can tell us the direction of change (warmer, drier, etc.) but not the amount of change (how warm? how dry?). Quantitative information is crucial to make speleothem-based data more useful to climate modellers and policy makers.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["691037"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["UNIVERSITEIT MAASTRICHT"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["Affective neurocognitive model for the \u2018Uncanny Valley\u2019"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["NEUROBUKIMI"], "Technology_Description": "The Uncanny Valley hypothesis (UV), proposed already 45 years ago, suggests that too humanlike robots or other artificial characters will elicit feelings of eeriness (Jpn. \u2018bukimi\u2019) in human observers. Existing psychological and neuroimaging studies have focused on the humanlikeness dimension of UV but neglected its emotional experience, which was at the heart of the original hypothesis. This interdisciplinary project will develop a thorough model for the emotional dimension of UV, consisting both of subjective verbal descriptions and observed neuronal activation patterns. A series of neuroimaging experiments will be carried out at the Brain and Emotion Laboratory of Maastricht University (UM): the first experiment will test the neuronal correlates of negative emotions elicited by semi-realistic virtual characters, and the second experiment will take a step beyond the original UV hypothesis by comparing the neuronal activation patterns of real and virtual emotional expressions. A self-report questionnaire for verbalizing the emotional experience of UV will be developed during a secondment period at Eindhoven University of Technology (Tu/e). By explicating the emotional experience of UV and by providing open tools for both research and industry, this project will be an important turning point for the future development of all humanlike technologies. Consistently, direct and concrete contacts with the animation industry are planned during the project. My supervisor Prof. de Gelder from UM is one of the thought leaders in the field of affective cognitive neuroscience, and my secondment supervisor Prof. Ijsselsteijn from Tu/e is renowned for his work in human-technology interaction. I am an experienced researcher with a dual background in both of these disciplines, as well as specific background in UV topic. This interdisciplinary synergy will maximize this project\u2019s impact on the European society and help establish my position as a leading independent scientist.", "To": ["2018-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-08-01"], "Project_ID": ["703493"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["VRIJE UNIVERSITEIT BRUSSEL", "UNIVERSITA DEGLI STUDI DI PADOVA", "IMEDICA SA", "ARTIA NANO - ENGINEERING & CONSULTING IKE", "INOCURE SRO"], "EU_Contribution": ["EUR 864 000"], "Project_Title": ["Enhanced brown adipose tissue activity using nanotechnology approaches"], "Total_Cost": ["EUR 864 000"], "Country": ["Belgium", "Italy", "Romania", "Greece", "Czech Republic"], "Project_ACR": ["nanoBAT"], "Technology_Description": "The use of nanotechnology and nano-materials in biological applications is being widely explored and is considered a valuable approach to ameliorate human wellbeing. Specifically, nanoparticles and carbon nanotubes are of great scientific interest as they are currently used clinically as delivery systems for a wide range of drugs. An interdisciplinary approach that considers knowledge in chemistry, nano-materials, toxicology, physiology, molecular biology is vital for the progress of these devices and for the development of new procedures to create a novel market-ready prototype to boost human metabolism, fighting obesity and cardio-metabolic disease. An inter-sectoral approach is also required to put together Academic\u2019s technical capabilities and facilities to conduct R&D activities with SMEs\u2019 business expertise and viable supply chain to develop the prototype post project and to exploit the product in the market. Therefore, two academic (VUB and UniPD) and three industrial (INOC, IMED, ARTIA) European participants will create an interdisciplinary and inter-sectoral co-operation (nanoBAT) to design and construct a novel nanostructured delivery-L-menthol system prototype for brown adipose tissue activation. During its four years duration, nanoBAT aims to achieve research and innovation objectives via staff exchanges of experienced and early-stage researchers throughout a series of activities like: networking, research and training, workshop, innovation, dissemination, and outreach.", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-02-01"], "Project_ID": ["691061"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["UNIVERSITEIT MAASTRICHT", "UNIVERSITEIT MAASTRICHT"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Silencing miR-199b to attenuate the progression of heart failure."], "Total_Cost": ["EUR 150 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["SIRENE"], "Technology_Description": "Cardiac hypertrophy is the principal risk factor for the development of heart failure and lethal arrhythmias. A complex web of interconnected signalling pathways has been implicated in hypertrophy and species of non-coding RNA molecules, microRNAs, have been shown to regulate these pathways. The recognition of microRNAs as potential therapeutic targets marks the principal step towards new therapeutic concepts. The SIRENE project represents the advancement of the therapeutic strength of miRNA silencing in clinically relevant heart failure models towards a valuable proposition for counteracting pathological hypertrophic signalling and heart failure development. In specific, during the related ERC CALMIRS project, it was found that sustained knockdown of endogenous miR-199b in the adult mouse heart in vivo leads to profound protective effects against symptoms of heart failure. Therefore, a new class of RNA antagonists, targeting miRNAs is powerful and holds great promise to become the next generation therapeutics. At this stage the newly developed antagonists are unique in their affinity and specificity for miR-199b and current data demonstrates a profound rescue by miR-199b antagonists on heart failure symptoms such as pressure overload induced cardiac morphological, histological, functional and molecular abnormalities in mice. The challenge of the SIRENE project is to identify immediate and longer term opportunities for commercialisation with high clinical and commercial feasibility. Therefore different business models will be studied in terms of market research, IP strategy and business development to eventually consolidate a commercial strategy and business case for presenting our business proposition to strategic partners or venture capitalists. Simultaneously, dose-range finding and efficacy studies will be conducted in rats, a clinically relevant and larger animal model of heart failure, for further preclinical development.", "To": ["2017-02-28, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2014 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["665647"], "Call_for_Proposal": ["ERC-2014-PoC"]}, -{"Partners": ["UNIVERSITEIT MAASTRICHT"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["Reducing Early Atrophy with Leucine during Immobilization of Skeletal Muscle"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["REALISM"], "Technology_Description": "Recovery from injury, illness, and/or disease is associated with skeletal muscle disuse. Muscle disuse leads to a loss of muscle mass, strength, and functional independence, and represents a \u201ccatabolic crisis\u201d for the elderly who are already at a greater risk for low muscle mass and strength due to age-related sarcopenia. Muscle mass is determined by the balance between muscle protein synthesis (MPS) and muscle protein breakdown (MPB). When MPB exceeds MPS, the result is a negative net protein balance and muscle loss. Decreased MPS rates occur following the onset of immobilization-induced disuse, but there is no information on the response of MPB. mRNA and protein expression data indicate that the early stages of disuse (0-5 days) result in activation of the ubiquitin proteasome system, and presumably MPB suggesting that the initial stages of disuse represent a critical period to intervene with appropriate countermeasures to attenuate the loss of muscle mass and strength. Leucine is a key amino acid in the regulation of muscle protein metabolism that has been shown to inhibit MPB. The current proposal REALISM will 1) identify whether MPB is elevated during the early stages (72 hours) of immobilization-induced disuse, 2) determine whether leucine can reduce MPB and the loss of muscle mass during the early stages of immobilization, and 3) determine whether leucine can preserve muscle mass and strength in the elderly during more prolonged periods of immobilization. REALISM will identify the mechanisms underlying disuse atrophy in response to immobilization and examine potential therapeutic strategies to offset the loss of muscle mass and strength. The M3 laboratory of Dr. van Loon at Maastricht University (UM) offers the most ideal environment for me to conduct REALISM, and take a major step towards the achievement of my career goal of setting up my own research program and establishing myself as an independent scientist.", "To": ["2017-04-30, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-05-01"], "Project_ID": ["659739"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY", "UNIVERSITAET ST. GALLEN", "STICHTING KATHOLIEKE UNIVERSITEIT BRABANT", "BABSON COLLEGE", "PEPPERDINE UNIVERSITY"], "EU_Contribution": ["EUR 180 000"], "Project_Title": ["A knowledge transfer and sharing action for developing A new integrative approach to mitigating errors in hospitals: Resolving tensions in error research"], "Total_Cost": ["EUR 337 500"], "Country": ["Israel", "Switzerland", "Netherlands", "United States", "United States"], "Project_ACR": ["Errspitals"], "Technology_Description": "Errors are a recurring fact of organizational life and the wisdom of managing and learning from errors is incontrovertible. In particular, medical errors in the health care industry, defined as avoidable adverse outcomes or injuries to patients stemming from healthcare processes, pose serious threats to human life and have an impact on total national costs. Yet, healthcare organizations that achieve a breakthrough in mitigating errors are extraordinarily rare. The aim of this Marie Sk\u0142odowska-Curie Actions proposal is thus to improve our understanding of the occurrence of medical errors and to develop a new, integrative approach to mitigating medical errors and promoting quality, efficiency, and innovativeness in hospitals. We strive for this goal by immersing ourselves in broad literature reviews and going beyond state of the art, collecting massive first-hand data in the hospital settings, and testing our working hypotheses on both qualitative and quantitative data. We envision three direct outcomes of our endeavor that are beneficial to both the academic community and heath care organizations. First, we will suggest an integrative theory of errors in organizations by identifying discrepancies, tensional issues, and opportunities for research synthesis via level of analysis and temporal and priority lenses. Second, we will develop an innovative, hybrid method to illuminate the errors phenomena and assess long-term effects of medical errors. Third, starting with the partnership between three participating research teams, we will create a long-lasting network that offers a rich resource for collaboration and knowledge-sharing that makes this resource more visible, inspectable, and systematic, which may aid the process of learning at a larger societal level.", "To": ["2018-12-31, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["690959"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["UNIVERSITEIT MAASTRICHT"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["Time of damage in classic galactosemia: is prenatal toxicity a determinant factor?"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["TIME"], "Technology_Description": "The TIME project aims to ascertain the time at which the toxicity observed in classic galactosemia begins, particularly if it begins prenatally. Recent advances in the molecular bases of classic galactosemia have taken research a step further towards therapy development. Therefore, it is of utmost importance to elucidate when the damage accurately begins, in order to define the time at which therapy should be initiated so that it can effectively prevent the development of long-term complications.", "To": ["2018-01-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["658967"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["INSTITUT DE PHYSIQUE DU GLOBE DE PARIS"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["3D Full Waveform Inversion on seismic data at the East Pacific Rise"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["3DWISE"], "Technology_Description": "The mid-ocean ridge system is the longest volcanic mountain chain that wraps around the Globe along which two plates have been separating and oceanic crust has been forming by highly active magmatic processes operating within and at the base of thus formed crust. It is believed that there is a strong link between these magmatic processes known at large spatial scales (1-100 km) and relatively localized (0.001-1 km) tectonic/ volcanic/hydrothermal/biological processes, and their expression onto the seafloor. However, the characteristics of the link are largely unknown. The origin of the most of the unknowns is embedded in poorly defined properties of the upper crust (its structure, P and S wave velocities, porosity, density, anisotropy, etc.), where the link is hosted and its activity is taking place. ", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["655283"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE"], "EU_Contribution": ["EUR 246 668,40"], "Project_Title": ["Reaching the roots of systemic nitrogen (N) signaling in plants"], "Total_Cost": ["EUR 246 668,40"], "Country": ["France"], "Project_ACR": ["Nitro Systems"], "Technology_Description": "The survival of multicellular organisms requires inter-organ communication via long-distance signals. This is especially relevant in plants where post-embryonic development can be altered in response to sensing a heterogeneous nutrient environment in the soil. For example, a long-distance, inter-organ \u201croot-shoot-root\u201d relay system enables plant roots to specifically forage for nitrate-rich patches in a heterogeneous nutrient soil environment . In this proposal, I will use a unique \u201csplit-root\u201d system to uncover the mechanisms of this systemic \u201croot-shoot-root\u201d relay system. Specifically, I will identify the targets of systemic N-signaling in plants as well as the potential RNA signals that traffic in phloem cells, the \u201cinformation highway\u201d to enable this inter-organ communication in plants. I will identify RNAs (mRNAs and smRNAs) associated with inter-organ signaling using a combination of time-based modeling and validate candidate genes using transgenics and shoot-root grafting. These studies will be the among the first to uncover systemic N-signals in a multicellular eukaryote.", "To": ["2018-08-31, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2015-09-01"], "Project_ID": ["659592"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITEIT MAASTRICHT"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["Towards Guaranteeing the Right to Effective Assistance of Defence Counsel in Member States in Trans-border Criminal Cases"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["ToEfDeCo"], "Technology_Description": "The right to effective assistance of defence counsel (READC) is one of the fundamental features of fair trial. In the context of open borders and increasing number of trans-border criminal cases it is important that all EU Member States (MS) guarantee the READC to suspects and requested persons in European arrest warrant cases at least on a minimum level. The Strasbourg system is no designed to achieve this goal, so the EU has taken the initiative via the Directive 2013/48/EU on the right of access to a lawyer in criminal proceedings etc. (22 Oct 2013). Considering the imminent transposition date of 27 Nov 2016, this project aims at determining how the MS are progressing in implementing the Directive. As the Directive not only guarantees the READC, but also requires that in case of breach of the READC, the MS have to ensure effective remedies, the final goal of the project is to propose remedies for trans-border cases that could be common to all MS. The research activities will be performed in the international environment of the Maastricht University, a centre of expertise on research on the READC in Europe, and will consist of two parts. ", "To": ["2017-12-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["654261"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITEIT MAASTRICHT"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["Mechanism Design under Incomplete Information"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["MEDINI"], "Technology_Description": "The purpose of this project is to study mechanism design under incomplete information with an emphasis on the design of voting procedures. Mechanism design is the commonly used term for the design of games with a certain objective. For instance, an auctioneer may wish to design an auction with the purpose of maximizing his own revenue. The usual assumption is that the mechanism designer does not know the preferences of the players, but the players do have this information. In this project, the latter assumption is dropped. For instance, in national elections voters have a tendency to vote strategically, and in general only have limited information about the preferences of the other voters. In that case, the objective of mechanism designer (designer of the voting system) is to elicit as much as possible the true votes (preferences), knowing that the voters have beliefs but no complete information about the preferences of the other voters. Specifically, the project will concentrate on three issues: how does correlation between the voters\u2019 beliefs effect the result of voting and how should the voting system be designed in order to elicit the true votes under this assumption of correlation; can we improve on the results of the first issue by allowing for probabilistic mechanisms, i.e., involve chance; and, following up on this, if truthful voting is out of reach, can we at least get the truthful voting result as an equilibrium outcome. The project is theoretical in nature but can lead to the design of experiments in particular testing the role of belief formation in voting. Further, the results of the project may lead to the design of improved smaller and larger scale voting procedures.", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["660341"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["PROVINCIA LOMBARDO VENETA - ORDINEOSPEDALIERO DI SAN GIOVANNI DI DIO- FATEBENEFRATELLI"], "EU_Contribution": ["EUR 180 277,20"], "Project_Title": ["Electrophysiological markers of cognitive processes and neuroplasticity in healthy ageing and Alzheimer`s disease"], "Total_Cost": ["EUR 180 277,20"], "Country": ["Italy"], "Project_ACR": ["NIBSAD"], "Technology_Description": "Ageing of the European population is increasing prevalence of age-related diseases such as Alzheimer\u2019s disease (AD). AD is considered a public health priority due to socio-economic costs and limited efficacy of current pharmacological treatments. Co-registration of electroencephalogram (EEG) and transcranial magnetic stimulation (TMS) is a novelty, non-expensive and non-invasive approach to obtain surrogate markers of cognitive decline. Moreover, repetitive TMS (rTMS) is considered a promising tool to induce neuroplasticity and improve cognitive functions. The main objective of this research is providing markers of brain activity, reactivity, connectivity and plasticity related with healthy and pathological ageing (i.e., early AD). Thus, samples of healthy young, healthy elderly and AD patients will perform a behavioural task (to study visuospatial attention and cognitive control processes) while carrying out EEG recording and online EEG/TMS co-registration. Correlates of brain activity (event-related brain potentials), reactivity (amplitude of TMS evoked potential -TEP) and connectivity (TEP topography, coherence, synchronization, and graph theoretical analysis of complex networks) will be obtained before and after of delivering offline rTMS. It will allow studying differences in cortical responses induced by rTMS on each group of participants, which will provide correlates and biomarkers of brain plasticity related with age and AD. These biomarkers will allow the identification of individuals at early stages of AD and evaluating efficacy of novel TMS treatments. Importantly, identification of rTMS parameters responsible to induce neural plasticity and improve cognitive functions will contribute to develop rehabilitation protocols for AD patients.", "To": ["2017-10-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations"], "From": ["2015-11-01"], "Project_ID": ["655423"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITEIT MAASTRICHT"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["Macrophage proliferation and ontogeny in murine models of atherosclerosis"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["Athero MPh proliferation"], "Technology_Description": "Atherosclerosis is a slowly progressing inflammatory disease that underlies some of the most common causes of death in western society. The central role of macrophages throughout its pathogenesis makes this cell an eminent target for therapeutic intervention. Recent studies have subverted the classical view that atherosclerotic plaque macrophages mainly originate from recruited circulating monocytes, launching the new notion that macrophages could also be derived from clonal expansion of resident macrophages or even trans-differentiated vascular smooth muscle cells. The relative importance of these mechanisms to the pathogenesis remains however unclear, due to a lack of adequate animal models that allow assessing this question.", "To": ["2018-01-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-02-01"], "Project_ID": ["661099"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Investigation and modification of atypical dynamic brain activity underlying perceptual inflexibility of autism spectrum disorders"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["AutismRigidPercept"], "Technology_Description": "Perceptual and cognitive inflexibility is considered to underlie the repetitive and restricted behaviours of autism spectrum disorder (ASD). However, despite its severe effects on daily life of autistic individuals, the biological basis of these ASD core symptoms remain little known. In this project, I will investigate the neural mechanisms behind this fundamental mental inflexibility of ASD by examining neural activity during bistable perception, which is thought to be suitable for evaluation of such mental and perceptual rigidity. To detect neural responses from the brains of autistic individuals during such fluctuating perceptual experience, I will empirically calculate the energy landscape of brain activity from non-invasive measurements of brain activity and numerically simulate activity transition on the energy surface. Given the explanatory power of this method demonstrated by my preliminary data, this project is expected to provide the first empirical evidence for autistic impairments in dynamic brain activity that underlies the mental inflexibility of ASD. Furthermore, successful completion of this main project will provide insight for a novel non-invasive intervention protocol to mitigate such autistic cognitive rigidity, which will be subsequently tested within this research project. I believe that this project has the potential to provide a novel integrative perspective to understand autistic cognitive inflexibility and presents a promising approach to modify these relatively overlooked symptoms.", "To": ["2017-04-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-05-01"], "Project_ID": ["656161"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["INSTITUT DE PHYSIQUE DU GLOBE DE PARIS"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Life in Arsenic rich environments: a challenge or an opportunity?"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["AsLife"], "Technology_Description": "Arsenic is a notorious toxin, and as such may have exerted a strong selective pressure on the distribution and evolution of life on Earth. Despite evidence supporting the high levels and prominent role of As on the primitive Earth, the essentiality and toxicity of As, and its impact on evolutionary processes remains unexplored. AsLife aims at taking a novel approach to assessing microbial As cycling by exploiting two linked \u00abenvironments\u00bb. The first are the microbial mats from High-Altitude Andean Lakes, where it is known that As concentrations are far above background levels. Specifically, living and diagenetically-modified microbial mats will be investigated using scanning hard X-ray nanoprobes emerging at synchrotron facilities. This non-invasive and non-destructive technique provides data on a sub-micrometer scale by which to tie physiological inference from trace metal(loid)s distribution and speciation patterns directly to the microfossil biomass. Thus, providing a means to understand the interplay between microbial metabolisms and bio-availability of trace metal(loid)s in living and fossil ecosystems. The second environment comprises laboratory cultures, using the sampling power of \u00abadaptive laboratory evolution\u00bb to explore how microbes adapt and enhance As detoxification facing the extreme As levels present in Andean Lakes. These results will be discussed in light of genomic studies of As-rich microbiota performed by Argentinian colleagues. ", "To": ["2018-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["701662"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITEIT MAASTRICHT"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["Audiovisual Speech Segmentation and Oscillations"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["AVISSO"], "Technology_Description": "Daily social tasks (e.g. meetings, shopping) rely on human communication with speech. Auditory only studies established that continuous speech segmentation relies on the temporal integration of rhythmic acoustic features occurring at delta-theta rates in the signal, via a possible mechanism of entrainment coupled with beta activity. In terms of neural correlates, the timing network (including the basal ganglia, supplementary motor area and cerebellum) may actively contribute to the temporal integration of auditory signal during continuous speech segmentation. However, speech is often multimodal and listeners need to integrate speaker\u2019s body movements aligned to rhythmic acoustic features. Consequently, AV speech may generate different rhythmic patterns than auditory only speech. How the brain translates naturally concomitant AV rhythms to facilitate speech segmentation clearly remains to be addressed. The goal of this project is to investigate the oscillatory patterns and neural correlates of AV rhythms resulting from the temporal integration of body movements and salient acoustic features in speech. In a first EEG experiment, I will compare the modulations of delta-theta entrainment and coupling with beta activity, depending on the relationship between visual and auditory information (congruent, incongruent and auditory only). Secondly, in an fMRI version of the experiment, I will explore the contribution of the timing network during AV speech segmentation, and its different patterns of activations across speech conditions. Finally, to test whether the brain areas revealed by fMRI have a necessary role for the successful AV speech segmentation, I will run the same fMRI experiment with Parkinson\u2019s disease patients with dysfunctional basal ganglia. Looking at the timing network patterns of activations will also reveal if correlated body information eventually help PD to compensate basal ganglia deficit with greater contribution of alternative path (i.e. cerebellum).", "To": ["2018-05-01, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-05-02"], "Project_ID": ["707727"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITEIT MAASTRICHT"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["MicroRNAs as therapeutic targets for ARVC."], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["MIRAGE"], "Technology_Description": "ARVC is a hereditary disease mainly characterised by the progressive substitution of the myocardium with fatty or fibro-fatty tissue involving predominantly the right ventricle. Clinically, ARVC shows wide variation between individuals. Together with modifier genes, common sequence variants, and environmental as well as endogenous factors, epigenetic modifiers such as miRNAs are hypothesized to be potential targets for disadvantageous environmental stimuli and may lead to the onset of complex and heterogeneous diseases such as ARVC. The main research objective of this EF is to assess and validate the relevance of disease mechanisms underlying the development of ARVC and to identify novel RNA-based targets in mouse models and ARVC patients. The EF programme comprises two tightly linked components \u2013 research and complementary training - that will be complemented with secondments in two (non-) academic organisations active in the field of molecular cardiology. The host organisations are strongly committed to enhancing the creative and innovative potential of the ER who wishes to diversify her individual competence in terms of skill acquisition to become a successful European scientist.", "To": ["2017-07-31, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-08-01"], "Project_ID": ["660440"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITEIT MAASTRICHT", "UNIVERSITEIT MAASTRICHT"], "EU_Contribution": ["EUR 1 361 507"], "Project_Title": ["The birth of the digital doctor? A comparative anthropology of medical techno-perception"], "Total_Cost": ["EUR 1 361 507"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["DigitalDoctors"], "Technology_Description": "Digital technologies are reconfiguring medical practices in ways we still don\u2019t understand. This research project seeks to examine the impact of the digital in medicine by studying the role of pedagogical technologies in how doctors learn the skills of their profession. It focuses on the centuries-old skill of physical examination; a sensing of the body, through the body. Increasingly medical students are learning these skills away from the bedside, through videos, simulated models and in laboratories. My research team will interrogate how learning with these technologies impacts on how doctors learn to sense bodies. Through the rich case of doctors-in-training the study addresses a key challenge in social scientific scholarship regarding how technologies, particularly those digital and virtual, are implicated in bodily, sensory knowing of the world. Our research takes a historically-attuned comparative anthropology approach, advancing the social study of medicine and medical education research in three new directions. First, a team of three ethnographers will attend to both spectacular and mundane technologies in medical education, recognising that everyday learning situations are filled with technologies old and new. Second, it offers the first comparative social study of medical education with fieldwork in three materially and culturally different settings in Western and Eastern Europe, and West Africa. Finally, the study brings historical and ethnographic research of technologies closer together, with a historian conducting oral histories and archival research at each site. Findings will have impact in the social sciences and education research by advancing understanding of how the digital and other technologies are implicated in skills learning. The study will develop novel digital-sensory methodologies and boldly, a new theory of techno-perception. These academic contributions will have practical relevance by improving the training of doctors in digital times.", "To": ["2021-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["678390"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["UNIVERSITATEA DIN BUCURESTI", "UNIVERSITATEA DIN BUCURESTI", "FUNDATIA NOUA EUROPA"], "EU_Contribution": ["EUR 671 875"], "Project_Title": ["Record-keeping, fiscal reform, and the rise of institutional accountability in late-medieval Savoy: a source-oriented approach"], "Total_Cost": ["EUR 671 875"], "Country": ["Romania", "Romania", "Romania"], "Project_ACR": ["CASTELLANY ACCOUNTS"], "Technology_Description": "The present research project focuses on an unjustly neglected corpus of late-medieval sources, the administrative and fiscal accounts (\u2018computi\u2019) of the castellanies \u2013 basic administrative units \u2013 of the county of Savoy. I propose a holistic model of analysis that can fully capitalise on the unusual wealth of detail of the Savoyard source material, in order to illuminate some key topics in late-medieval institutional and socio-economic history, from the development of state institutions through administrative and fiscal reform \u2013 with particular attention to the transition from personal to institutional accountability \u2013 to the question of socio-economic growth, decline, and recovery during the turbulent period of the late-thirteenth to the late-fourteenth century. More broadly, my research into these topics aims to contribute to our understanding of the late-medieval origins of European modernity. The advances of pragmatic literacy, record-keeping, and auditing practices will be analysed with the aid of anthropological and social scientific theories of practice. By comparing the Savoyard \u2018computi\u2019 with their sources of inspiration, from the Anglo-Norman pipe rolls to the Catalan fiscal records, the project aims to highlight the creative adaptation of imported administrative models, and thus to contribute to our knowledge of institutional transfers in European history. The project will develop an inclusive frame of analysis in which the \u2018computi\u2019 will be read against the evidence from enfeoffment charters, castellany surveys (\u2018extente\u2019), and the records of direct taxation (\u2018subsidia\u2019). The serial data will be analysed by building a database; the findings of quantitative analysis will be verified by case studies of the individuals and families (many from the middle social strata) that surface in the fiscal records.", "To": ["2020-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Romania"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2015-05-01"], "Project_ID": ["638436"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["RUHR-UNIVERSITAET BOCHUM", "RUHR-UNIVERSITAET BOCHUM", "BAYERISCHE JULIUS-MAXIMILIANS UNIVERSITAT WURZBURG"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Tailoring Ylidic Compounds as Ligands for Organometallic Chemistry"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Germany", "Germany", "Germany"], "Project_ACR": ["YlideLigands"], "Technology_Description": "Lewis bases are a fundamental class of compounds that are of utmost importance in almost any chemical transformation. According to the HSAB concept, they determine important properties such as the stability or solubility of compounds or the selectivity of reactions. Yet, Lewis bases are used far beyond simple acid-base pairs. In coordination chemistry they act as efficient \u03c3-donor ligands, which crucially affect the electronics of the metal and thus its reactivity. Additionally, bulky Lewis bases as part of Frustrated Lewis Pairs are applicable in bond activation reactions and also in catalysis. Typical Lewis bases are neutral compounds with a free pair of electrons, such as amines or phosphines. In contrast, carbon-centred Lewis bases such as carbenes have long been underestimated due to their usually high reactivity and sensitivity. Yet, the last decades have revealed a revolution in this context. Carbenes in particular have proven to be powerful reagents not only as ligands, but also in organocatalysis and bond activation chemistry. Bisylides and their dianionic congeners (methandiides) with formally two electron pairs at carbon are further classes of carbon bases that have started to find applications, but which are still profoundly underdeveloped. ", "To": ["2021-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-07-01"], "Project_ID": ["677749"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["RUHR-UNIVERSITAET BOCHUM", "RUHR-UNIVERSITAET BOCHUM"], "EU_Contribution": ["EUR 1 394 040"], "Project_Title": ["How and when was Japan settled by speakers of Japanese? Exploring the clues to Japanese prehistory preserved in old dialect divisions"], "Total_Cost": ["EUR 1 394 040"], "Country": ["Germany", "Germany"], "Project_ACR": ["JapPrehistMigration"], "Technology_Description": "It is thought that the Japanese language was brought to Japan in a series of west-to-east migrations from the Korean peninsula in prehistoric times. Through fieldwork on the tone systems of a cluster of outlying and not sufficiently documented dialects in Japan (the so-called Gairin or \u2018outer circle\u2019 dialects), a genealogy of the members of this dialect group will be reconstructed. ", "To": ["2021-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["677317"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["INSTITUT DE PHYSIQUE DU GLOBE DE PARIS", "INSTITUT DE PHYSIQUE DU GLOBE DE PARIS"], "EU_Contribution": ["EUR 1 487 500"], "Project_Title": ["High precision isotopic measurements of heavy elements in extra-terrestrial materials: origin and age of the solar system volatile element depletion"], "Total_Cost": ["EUR 1 487 500"], "Country": ["France", "France"], "Project_ACR": ["PRISTINE"], "Technology_Description": "\"The objectives of this proposal, PRISTINE (high PRecision ISotopic measurements of heavy elements in extra-Terrestrial materials: origIN and age of the solar system volatile Element depletion), are to develop new cutting edge high precision isotopic measurements to understand the origin of the Earth, Moon and solar system volatile elements and link their relative depletion in the different planets to their formation mechanism. In addition, the understanding of the origin of the volatile elements will have direct consequences for the understanding of the origin of the Earth\u2019s water. To that end, we will approach the problem from two angles: 1) Develop and use novel stable isotope systems for volatile elements (e.g. Zn, Ga, Cu, and Rb) in terrestrial, lunar and meteoritic materials to constrain the origin of solar system\u2019s volatile element depletion 2) Determine the age of the volatile element depletion by using a novel and original approach: calculate the original Rb/Sr ratio of the Solar Nebula by measuring the isotopic composition of the Sun with respect to Sr via the isotopic composition of solar wind implanted in lunar soil grains.", "To": ["2020-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-04-01"], "Project_ID": ["637503"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["HUMBOLDT-UNIVERSITAET ZU BERLIN"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Physical Activities of Older Adults: Longitudinal Interdisciplinary Analysis"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["PAOLInA"], "Technology_Description": "The PAOLInA-project focuses on physical activities of older citizens of European countries. It begins with the analysis of the phenomenon \u201cphysical activities\u201d, and their change in the course of the late and latest years of life. The goal is to show what is covered by the term \u201cphysical activities\u201d (PAs), and to differentiate PAs into domains according to their purpose (e.g. sports in leisure time, PA for self-care, PA as form of transportation). The Experienced Researcher (ER) hypothesizes that the overall involvement of older adults in PA does not necessarily decline as the individuals are getting older, but that some types of activities may even increase or replace others. If these interdependencies are neglected in the measurement older adults may appear as more sedentary than they actually are. The ER will also examine the factors that influence the change of the PAs. She will look at the interplay between individual characteristics and the attributes of people\u2019s living environments. As a result, patterns of PA promoting factors will be carved out. The research will be based on secondary analysis of various longitudinal data sets, such as the German Socioeconomic Panel (SOEP) and the Survey of Health and Retirement in Europe (SHARE). Multilevel modelling will be applied in the statistical analyses. Thus, the PAOLInA-project is innovative in several respects: It will differentiate the PAs, which \u2013 according to the state of the existing research \u2013 has rarely been the case. It will reveal the long-term developments in older adults\u2019 engagement and involvement in PAs. It will match individual characteristics with environmental and regional indicators. The ER will introduce her perspective of health psychology into an institute that does not have this specialization yet. She will benefit from the excellent methodological expertise of her prospective supervisor, additional training and support from the partners, and get access to a European network of collaborators.", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["661555"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITEIT MAASTRICHT", "UNIVERSITEIT MAASTRICHT"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Imaging Brain Circuits to Decode Brain Computations: Multimodal Multiscale Imaging of Cortical Microcircuits to Model Predictive Coding in Human Vision"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["MULTICONNECT"], "Technology_Description": "The human brain is one of the largest and most complex biological networks known to exist. The architecture of its circuits, and therefore the computational basis of human cognition, remains largely unknown. The central aim of this proposal is to image human cortical connectivity at multiple spatial scales in order to understand human cortical computations. ", "To": ["2020-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-06-01"], "Project_ID": ["639938"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["INSTITUT DE PHYSIQUE DU GLOBE DE PARIS", "INSTITUT DE PHYSIQUE DU GLOBE DE PARIS"], "EU_Contribution": ["EUR 1 999 250"], "Project_Title": ["Tracing ancient microbial cells embedded in silica"], "Total_Cost": ["EUR 1 999 250"], "Country": ["France", "France"], "Project_ACR": ["TRACES"], "Technology_Description": "Reconstructing the nature and habitat of early life is a difficult task that strongly depends on the study of rare microfossils in the ancient rock record. The preservation of such organic structures critically depends on rapid entombment in a mineral matrix. Throughout most of Earth\u2019s history the oceans were silica-supersaturated, leading to precipitation of opal deposits that incorporated superbly preserved microbial cells. As we trace this record of life back in deep time, however, three important obstacles are encountered; 1) microorganisms lack sufficient morphologic complexity to be easily distinguished from each other and from certain abiologic microstructures, 2) the ancient rock record has been subjected to increased pressures and temperatures causing variable degradation of different types of microorganism, and 3) early habitats of life were dominated by hydrothermal processes that can generate abiologic organic microstructures. TRACES will study the critical transformations that occur when representative groups of microorganisms are subjected to artificial silicification and thermal alteration. At incremental steps during these experiments the (sub)micron-scale changes in structure and composition of organic cell walls are monitored. This will be compared with fossilized life in diagenetic hot spring sinters and metamorphosed Precambrian chert deposits. The combined work will lead to a dynamic model for microfossil transformation in progressively altered silica-matrices. The critical question will be answered whether certain types of microorganisms are more likely to be preserved than others. In addition, the critical nano-scale structural differences will be determined between abiologic artefacts \u2013 such as carbon coatings on botryoidal quartz or adsorbed carbon on silica biomorphs \u2013 and true microfossils in hydrothermal cherts. This will provide a solid scientific basis for tracing life in the oldest, most altered part of the rock record.", "To": ["2020-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-05-01"], "Project_ID": ["646894"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["THE ROYAL VETERINARY COLLEGE", "THE ROYAL VETERINARY COLLEGE"], "EU_Contribution": ["EUR 2 498 718,76"], "Project_Title": ["Testing the locomotor superiority hypothesis for early dinosaurs"], "Total_Cost": ["EUR 2 498 718,76"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["DAWNDINOS"], "Technology_Description": "I seek to unify evolutionary and biomechanical research by achieving a \u201cfunctional synthesis\u201d in evolution that causally links phenotypes (anatomy) to actual performance. Did early, bipedal dinosaurs evolve advantages in their locomotor performance over other Late Triassic archosaurs (\u201cruling reptiles\u201d)? This \u201clocomotor superiority\u201d hypothesis was first proposed to explain what made dinosaurs distinct from other Triassic taxa, perhaps aiding their survival into the Jurassic. However, the hypothesis remains untested or unfairly dismissed. I will test this question for the first time, but first I need to develop the best tools to do so. ", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["695517"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["THE HEBREW UNIVERSITY OF JERUSALEM", "THE HEBREW UNIVERSITY OF JERUSALEM", "NEW YORK UNIVERSITY"], "EU_Contribution": ["EUR 1 808 000"], "Project_Title": ["Forecasting Surface Weather and Climate at One-Month Leads through Stratosphere-Troposphere Coupling"], "Total_Cost": ["EUR 1 808 000"], "Country": ["Israel", "Israel", "United States"], "Project_ACR": ["FORECASToneMONTH"], "Technology_Description": "Anomalies in surface temperatures, winds, and precipitation can significantly alter energy supply and demand, cause flooding, and cripple transportation networks. Better management of these impacts can be achieved by extending the duration of reliable predictions of the atmospheric circulation. ", "To": ["2021-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["677756"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["UNIVERSITEIT MAASTRICHT", "UNIVERSITEIT MAASTRICHT"], "EU_Contribution": ["EUR 1 937 500"], "Project_Title": ["Mobility trajectories of young lives: Life chances of transnational youths in Global South and North"], "Total_Cost": ["EUR 1 937 500"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["MO-TRAYL"], "Technology_Description": "The objective of MO-TRAYL is to develop a better understanding of the relationship between migration and young people\u2019s life-chances by studying youth\u2019s mobility trajectories. How the life chances of youths, defined as their educational performance, psychological well-being and transitions into adulthood, are impacted by migration are of relevance for European cities that are faced with a growing youth population with migrant background. At the same time, cities in the Global South, where many migrants in Europe originate from, are faced with large portions of the population of minors who are living without at least one of their parents due to their parent\u2019s migration. There is growing concern in both academia and policy about how these \u2018stay-behind\u2019 children are faring. Yet little is known about how migration impacts young people in the Global North and South in the medium-term, in part because our conception of young people\u2019s mobility patterns has to date been overly simplified (either they move once, or they do not). This results in a lack of data that specifically looks at the different mobility patterns of young people and hardly any that has a longitudinal dimension. MO-TRAYL will break new ground by studying simultaneously youths in the Global South who have remained \u2018at home\u2019 and those who have migrated to Europe by making use of unique new longitudinal data collected in the Global South as well as collecting new data in the Global North that specifically traces the mobility trajectories, the resulting different family compositions along the way, and how both affect life chances. Through a transnational perspective in which family members and events spanning home and host countries are brought to bear on life chances, MO-TRAYL aims to re-conceptualize youth mobility and families and add a longitudinal dimension to the study of migration and life chance outcomes. The project focuses on Ghanaian children in Ghana, The Netherlands, Belgium and Germany.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["682982"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN", "OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN", "RUHR-UNIVERSITAET BOCHUM"], "EU_Contribution": ["EUR 1 498 452"], "Project_Title": ["Transmission of Classical Scientific and Philosophical Literature from Greek into Syriac and Arabic"], "Total_Cost": ["EUR 1 498 452"], "Country": ["Austria", "Austria", "Germany"], "Project_ACR": ["HUNAYNNET"], "Technology_Description": "It is often taken for granted that the Greek-Arabic translation movement (8th-10th c.) that made the whole bulk of Classical Greek scientific and philosophical literature available in Arabic (and that was later handed over to Europe in Latin translations) owes much to the preceding period in the history of transmission of this scientific and philosophical literature, namely translations into the Syriac language that were implemented by Aramaic-speaking Syriac Christians. The problem of continuity between the two periods however has not been tackled thoroughly in scholarship and thus the actual impact of the Syriac translations on later methods of translation has so far not been measured and assessed. One feasible solution to this problem in our understanding of the background to the Greek-Arabic translation movement is to implement a comprehensive comparison of Syriac and Arabic translations by means of lexicographical analysis. This project offers a research tool capable of allowing this comparison. It will combine methods of online lexicography and of corpus linguistics with the aim of presenting in a systematic and rationalized way the lexical data from the entire corpus of Syriac scientific and philosophical translations, comparing and analyzing its terminology and translation techniques, first, with the extant Greek originals and, secondly, with Arabic versions. The lexicographic database will be an effective instrument providing definite data for the study of Syriac and Arabic translations and their close connections. It will reveal how the Syriac translations along with underlying methods and tools that were put to use for the first time ever by Syriac Christians eventually determined the prosperity of the Islamic sciences. Fully endorsing a principle of open access the database creates a new instrument for a study of the history of the transmission of Greek scientific literature in Antiquity and the Middle Ages.", "To": ["2021-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Austria"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["679083"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["RUHR-UNIVERSITAET BOCHUM", "RUHR-UNIVERSITAET BOCHUM"], "EU_Contribution": ["EUR 2 498 286"], "Project_Title": ["Exploring and Preventing Cryptographic Hardware Backdoors: Protecting the Internet of Things against Next-Generation Attacks"], "Total_Cost": ["EUR 2 498 286"], "Country": ["Germany", "Germany"], "Project_ACR": ["EPoCH"], "Technology_Description": "The digital landscape is currently undergoing an evolution towards the Internet of Things. The IoT comes with a dramatically increased threat potential, as attacks can endanger human life and can lead to a massive loss of privacy of (European) citizens. A particular dangerous class of attacks manipulates the cryptographic algorithms in the underlying hardware. Backdoors in the cryptography of IoT devices can lead to system-wide loss of security. This proposal has the ambitious goal to comprehensively understand and counter low-level backdoor attacks. The required research consists of two major modules:", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["695022"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["THE UNIVERSITY OF HERTFORDSHIRE HIGHER EDUCATION CORPORATION"], "EU_Contribution": ["EUR 251 857,80"], "Project_Title": ["Information Theoretic Evaluation of Random Content Generation in Games"], "Total_Cost": ["EUR 251 857,80"], "Country": ["United Kingdom"], "Project_ACR": ["INTERCOGAM"], "Technology_Description": "INTERCOGAM\u2019s goal is to develop and use information theory based intrinsic motivation formalisms to evaluate automatically generated game mechanics. Content generation is one of the production bottlenecks of professional game design, which has begun to be addressed by procedural content generation. In this field, search based procedural content generation uses the idea of evolutionary algorithms to represent, modify and adapt games and game content to maximise fun and engagement with the game. One major challenge here is the identification of widely applicable fitness functions, which capture the different aspects of what makes a game fun, such as challenge level, complexity, pacing, etc. INTERCOGAM will relate psychological and game design concepts of game experience to either existing formalisms for intrinsic motivation or develop new ones, where appropriate. Human play testers will then play procedurally generated games and evaluate their own experience, allowing us to verify whether our formalism captures the actual human motivation, and whether humans indeed act according to certain intrinsic motivations. INTERCOGAM will yield both, a tool to generate new and engaging game ideas, aiding better and faster game design, and provide new insights into how the human mind engages with different worlds where there is no external reward present.", "To": ["2019-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-12-01"], "Project_ID": ["705643"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["RUHR-UNIVERSITAET BOCHUM", "RUHR-UNIVERSITAET BOCHUM", "WEIZMANN INSTITUTE OF SCIENCE"], "EU_Contribution": ["EUR 2 500 000"], "Project_Title": ["Time Resolved THz Calorimetry explores Molecular Recognition Processes"], "Total_Cost": ["EUR 2 500 000"], "Country": ["Germany", "Germany", "Israel"], "Project_ACR": ["THZCALORIMETRY"], "Technology_Description": "Time-resolved THz-Calorimetry Explores Molecular Recognition Processes", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["695437"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["INSTITUT DE PHYSIQUE DU GLOBE DE PARIS"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["To understand the redox variations and interactions between hydro-, bio- and atmosphere: the power of bromine stable isotopes."], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["BRISOACTIONS"], "Technology_Description": "The stable isotope geochemistry of chlorine (Cl) and bromine (Br) are considerably different. While most Cl isotope data are in the range from -1.21 to +0.40\u2030, Br isotope data are from -0.06 to +1.48\u2030. Interesting is that Br isotope variations are of the same magnitude as Cl isotope variations. Also Br isotope values of ancient evaporites are very positive (+0.6\u2030), impossible to explain from oceans with a modern isotope composition. These data are unexpected considering the small fractionation factors for Br compared to Cl.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["702001"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["RUHR-UNIVERSITAET BOCHUM", "RUHR-UNIVERSITAET BOCHUM"], "EU_Contribution": ["EUR 1 472 268,75"], "Project_Title": ["Leveraging Binary Analysis to Secure the Internet of Things"], "Total_Cost": ["EUR 1 472 268,75"], "Country": ["Germany", "Germany"], "Project_ACR": ["BASTION"], "Technology_Description": "We are in the midst of the shift towards the Internet of Things (IoT), where more and more (legacy) devices are connected to the Internet and communicate with each other. This paradigm shift brings new security challenges and unfortunately many current security solutions are not applicable anymore, e.g., because of a lack of clear network boundaries or resource-constrained devices. However, security plays a central role: In addition to its classical function in protecting against manipulation and fraud, it also enables novel applications and innovative business models. ", "To": ["2020-02-29, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-03-01"], "Project_ID": ["640110"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["INSTITUTE OF EXPERIMENTAL MEDICINE - HUNGARIAN ACADEMY OF SCIENCES"], "EU_Contribution": ["EUR 245 250"], "Project_Title": ["Deciphering the cholinergic modulation of the hippocampal place code."], "Total_Cost": ["EUR 245 250"], "Country": ["Hungary"], "Project_ACR": ["HippAchoMod"], "Technology_Description": "Acetylcholine released by cholinergic neurons in the basal forebrain is a critical component of the modulatory cocktail governing the emergence, stabilization and reorganization of cortical ensembles of co-active neurons representing the environment. In the hippocampus, ACh renders the state of the network optimal for the acquisition of novel information. Deterioration of cholinergic modulation leads to severe deficits in hippocampal function manifested as debilitating cognitive impairments. Despite decades of intense research fundamental questions are still open about the cholinergic modulation of hippocampal information processing: i) how is the behaviour-dependent firing of different neuron types determined by ACh? ii) how does ACh contribute to the emergence of the spatially selective firing of principal cells, their amalgamation into sequences representing the surroundings of the animal and the storage of \u201crelevant\u201d sequences? iii) how does ACh alter the place code in response to salient environmental stimuli? Technological breakthroughs of the past years have opened the possibilities of addressing these long-standing questions about cholinergic modulation. Thus, I aim to combine the latest electrophysiological recording, optogenetic manipulation and behavioural tracking methods to monitor hippocampal neuronal ensembles in freely behaving mice while manipulating the cholinergic input of the hippocampus by light-responsive microbial opsins. Results of the proposed research programme will decipher the role of ACh in hippocampal information processing and inform us how subcortical modulation contributes to the conversion of external inputs from the environment to internal representations. By accomplishing the programme outlined in the proposal I will be acquainted with the cutting edge technologies as well as skills indispensable for starting my independent research group and expanding the research potential of my home institute.", "To": ["2019-08-07, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Hungary"], "Activity": ["Research Organisations"], "From": ["2016-08-08"], "Project_ID": ["707359"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITEIT MAASTRICHT"], "EU_Contribution": ["EUR 174 864,60"], "Project_Title": ["Connecting neuronal network activity with regional specificity for Alzheimer pathology: a multi-modal neuroimaging approach"], "Total_Cost": ["EUR 174 864,60"], "Country": ["Netherlands"], "Project_ACR": ["CONNECT"], "Technology_Description": "As the world\u2019s population is aging, the prevalence of Alzheimer\u2019s disease (AD) is estimated to triple by 2050. Even though AD was identified more than 100 years ago, research has gained momentum only the last 30 years. To date, studies have mainly focused on the accumulation of two proteins, amyloid-beta and tau to understand the pathophysiology of this disease. In this project, I will take a new approach, by investigating the interaction between these two pathological hallmarks of AD and neuronal activity as a potential causal model for AD. The underlying hypothesis is that regional levels of neuronal activity determine the interaction between amyloid and tau pathology, and lead to AD symptomatology. To that end, I aim to combine novel molecular and state-of-the-art magnetic neuroimaging techniques with higher statistical modeling techniques. The group of Prof. Johnson at Massachusetts General Hospital (MGH) is currently the leading group pushing these techniques forward. The expertise within the lab of Prof. Johnson, his extensive network, the skills that I will acquire throughout this fellowship (scientifically and management-wise), combined with my existing level of expertise in MRI and my participation in diverse European networks will provide me with the competences to lead my own research group and establish a functional international multidisciplinary AD research network. Delaying or even treating this disease will require a multifactorial, multidisciplinary approach in which researchers combine resources, data and results in a coordinated manner worldwide. The implementation of these techniques in Europe and the subsequent close collaborations between European and American networks will have the highest chances to improve detection, prevention and treatment of AD.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["706714"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITEIT UTRECHT"], "EU_Contribution": ["EUR 260 929,80"], "Project_Title": ["Towards the selective hydrodeoxygenation and hydrogenation of levoglucosenone using base metal heterogeneous catalysts modified by atomic layer deposition"], "Total_Cost": ["EUR 260 929,80"], "Country": ["Netherlands"], "Project_ACR": ["TAILORCAT"], "Technology_Description": "Catalytic technology has advanced markedly throughout the 20th century, refining the catalytic processes that provide us with fuels and base chemicals. Presently some important challenges in catalyst development are:", "To": ["2020-06-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-15"], "Project_ID": ["701028"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 212 463"], "Project_Title": ["Operation Condor: Accountability for Transnational Crimes in Uruguay"], "Total_Cost": ["EUR 212 463"], "Country": ["United Kingdom"], "Project_ACR": ["Operation Condor"], "Technology_Description": "Confronting past atrocities is essential to consolidate democracy and human rights protection. Truth and justice initiatives investigating crimes perpetrated at the national level have long been occurring. Yet, accountability for transnational crimes is a pending issue in scholarship and practice. ", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-08-01"], "Project_ID": ["702004"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITEIT MAASTRICHT", "UNIVERSITEIT MAASTRICHT"], "EU_Contribution": ["EUR 2 499 399"], "Project_Title": ["Tackling the Achilles Heel of Immunotherapy: Validating imaging biomarkers and targeting the immunological niche of tumour hypoxia"], "Total_Cost": ["EUR 2 499 399"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["HYPOXIMMUNO"], "Technology_Description": "Lung cancer is the most common cause of death from cancer worldwide with 1.59 million deaths annually and it places the highest economic burden of all cancers on the EU at \u20ac18.8billion. These figures call for a major transformation of the therapeutic management of lung cancer. The recent developments in immunotherapy give new hope. At present a significant minority of patients benefit from immune therapy, which remains not curative when delivered alone. It is thus clear that improving the efficacy of immune therapy is needed as well as the identification of predictive biomarkers. Combining immunotherapy with radiotherapy improves effectiveness, but resistance is still common, most probably because of hypoxia. In HYPOXIMMUNO, we will open up a new paradigm in treating metastatic NSCLC. I will provide for the first time (pre)clinical proof of concept of (i) highly innovative CT-based radiomics and PET-hypoxia imaging patient stratification tools and (ii) a tri-modal curative hypoxia-targeting treatment strategy that complements current immunotherapy and radiotherapy approaches. This tri-modal curative treatment strategy is based on (1) high precision Stereotactic Radiotherapy (SABR) to kill cancer cells and trigger the immune system, combined with (2) a hypoxia-activated prodrug to target the hypoxic tumour cells resistant to immunotherapy and (3) a promising and innovative tumour specific antibody (Ab)-based immunotherapy (immunocytokine L19-IL2 to \u201cpush the accelerator\u201d with or without a checkpoint inhibitor to \u201crelease the break\u201d) to form a powerful synergistic immuno-oncology strategy. In HYPOXIMMUNO, I envision to lay the foundation for the next breakthrough in oncology, by improving patient selection and developing highly innovative cancer therapies that target hypoxia, to improve the quality of life and prolong survival of cancer patients, in particular patients with metastatic NSCLC (watch the animation summarising the project: https://youtu.be/oP9Gp4a0b_Q).", "To": ["2021-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-12-01"], "Project_ID": ["694812"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["UNIVERSITEIT LEIDEN"], "EU_Contribution": ["EUR 242 929,80"], "Project_Title": ["Perceptions of threat to personal values shape punishment judgments through social identity threat"], "Total_Cost": ["EUR 242 929,80"], "Country": ["Netherlands"], "Project_ACR": ["ThreatValPun"], "Technology_Description": "In modern societies, the criminal justice system is entrusted to punish norm violators in a fair and impartial way. Yet, punishment judgments are subject to biases, and are sometimes shaped by extralegal factors, as illustrated for example by the over-representation of African-Americans in inmates in the US. This project investigates one such factor, namely perceived threats to one\u2019s personal values. We argue that even when unrelated to the wrongdoing, value-violations represent a threat to one\u2019s personal values and to one\u2019s identity. As such, value-violations trigger a motivation to restore the threatened values and identity, leading to differential punishment judgments as a function of the target\u2019s fit or misfit with the perceiver\u2019s values. We test this crucial role of perceptions of threat to personal values in two lines of research, using a combination of traditional experimental research methods, and modern measurement methods. In the line of research A, we aim to identify moderators of the effect of personal value on punishment judgments. Experimentally increasing or removing threat to values will allow us to gain a clearer understanding of the causal processes at play. In the line of research B, we aim to identify the neural processes underlying the effects of perceptions of threat to personal values on punishment judgments. Using fMRI, lesion patients and cardiovascular indices, we will gain complementary perspectives on the dynamics at play. As a result, the present proposal will enhance knowledge in the fields of values, social justice and morality, but also offer applicable strategies to reduce the impact of threat to values on real-life potentially consequential judgments, for example in the legal system.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["703401"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITEIT MAASTRICHT", "UNIVERSITEIT MAASTRICHT"], "EU_Contribution": ["EUR 2 655 000"], "Project_Title": ["Building complex life through self-organization: from organ to organism"], "Total_Cost": ["EUR 2 655 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["ORCHESTRATE"], "Technology_Description": "A major challenge in regenerative medicine is to create phenotypic functioning tissues by controlling cell behaviour. We particularly lack the ability to form complex tissues composed of multiple cell types and with three-dimensional architecture, which are defining features of most tissues. We know that cells are conferred with the ability to choreograph their own development through self-organization. I hypothesize that if we actively promote this intrinsic capacity with new cell culture platforms, we can orchestrate self-organization to make complex tissues, organs, and even organisms with a high degree of reproducibility and in large numbers. ", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["694801"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["RUHR-UNIVERSITAET BOCHUM", "RUHR-UNIVERSITAET BOCHUM"], "EU_Contribution": ["EUR 1 497 916,26"], "Project_Title": ["From Supramolecular Chemistry to Organocatalysis: Fundamental Studies on the Use of Little-Explored Non-Covalent Interactions in Organic Synthesis"], "Total_Cost": ["EUR 1 497 916,26"], "Country": ["Germany", "Germany"], "Project_ACR": ["XBCBCAT"], "Technology_Description": "Hydrogen-bonds have found widespread use in various fields of chemistry, including supramolecular chemistry, organic chemistry, and more lately organocatalysis. Although a multitude of structurally different hydrogen-bond donors has been developed, their mode of action is in all cases necessarily based on the same interacting atom, hydrogen. ", "To": ["2020-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-05-01"], "Project_ID": ["638337"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["THE ROYAL VETERINARY COLLEGE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Evaluations of bone strength in the evolutionary invasion of land by tetrapods"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["TETRAPODBONES"], "Technology_Description": "How tetrapods (vertebrates with digit-bearing limbs) became terrestrial is one of the most transformative yet enigmatic events in vertebrate history that set the stage for the diversification of tetrapods thereafter. Being on land imposes physical demands on the musculoskeletal system and weak bones can severely limit the capabilities of animals, yet the importance of bone strength in the evolution of terrestrial locomotion is not well understood. The proposed research integrates innovative approaches on the limbs of an early stem tetrapod, Ichthyostega, in order to: 1) quantify how well the limb bones in an early stem tetrapod could support locomotion on land, 2) compare the differences between the fore- and hindlimb bone mechanics, and 3) test the prevailing hypothesis that early stem tetrapods walked like extant salamanders. An interdisciplinary synthesis of cutting-edge techniques in engineering, 3D biomedical imaging, palaeontology, and biomechanics will be used to test the structural integrity of fossil limb bones in silico. Bone strength will be quantified with high-resolution \u03bc-CT scans and finite element analysis, an engineering approach to estimate stresses and deformations in complex structures in response to physical demands. This novel dataset will address the ability of Ichthyostega to move on land, and what types of locomotor behaviours were not possible for an early stem tetrapod on land. Simultaneously, training and research activities in state-of-the-art engineering and 3D technology, evolutionary biomechanics, and public outreach will foster the development of the Experienced Researcher (ER) into an innovative and broadly trained researcher and science communicator. At a broader scale, tracing back the evolutionary steps to becoming terrestrial yields powerful insights into the tetrapod body plan, informing how ecological transitions influence functional innovation and how human anatomy is influenced by our ancestry from aquatic tetrapods.", "To": ["2018-08-21, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-08-22"], "Project_ID": ["703516"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["BSH ELECTRODOMESTICOS ESPANA SA"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["New engineered surfaces for a better life"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["ENSUR4LIFE"], "Technology_Description": "Surface anti-condensation and/or anti-biofouling (by surface wettability control) are very interesting and useful properties aimed by industry as they can offer more energy efficient, easy-cleanable or more hygienic products. In the last years, new non-conventional techniques have been developed in order to provide those new functionalities by physical surface modification (avoiding chemical coatings or doping bulk materials). But up to the moment, a technology able to respond to hard industrial requirements as home appliances (i.e. durability, severe boundary conditions, low cost) has not been achieved.", "To": ["2017-04-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["Spain"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-05-01"], "Project_ID": ["654963"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITA CA' FOSCARI VENEZIA"], "EU_Contribution": ["EUR 168 277,20"], "Project_Title": ["\u201cThomas Aquinas\u2019 Summa Theologiae Ia IIae translated by Demetrius Cydones and Bessarion\u2019s incomplete Compendium of the translation \u2013 A Critical Editio Princeps\u201d"], "Total_Cost": ["EUR 168 277,20"], "Country": ["Italy"], "Project_ACR": ["TASTGCEP"], "Technology_Description": "The proposed Project is the critical edition (editio princeps) of the Greek translation of Thomas Aquinas\u2019 Summa Theologiae Ia IIae by Demetrios Cydones and of its partial Compendium by Cardinal Bessarion. ", "To": ["2018-10-02, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-10-03"], "Project_ID": ["703595"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITEIT MAASTRICHT", "UNIVERSITEIT MAASTRICHT"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["3D Scaffolds as a Stem Cell Delivery System for Musculoskeletal Regenerative Medicine"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["CELL HYBRIDGE"], "Technology_Description": "Aging worldwide population demands new solutions to permanently restore damaged tissues, thus reducing healthcare costs. Regenerative medicine offers alternative therapies for tissue repair. Although first clinical trials revealed excellent initial response after implantation of these engineered tissues, long-term follow-ups demonstrated that degeneration and lack of integration with the surrounding tissues occur. Causes are related to insufficient cell-material interactions and loss of cell potency when cultured in two-dimensional substrates, among others.", "To": ["2020-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-05-01"], "Project_ID": ["637308"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["DUBLIN INSTITUTE FOR ADVANCED STUDIES"], "EU_Contribution": ["EUR 187 866"], "Project_Title": ["Disclosing the Inner Gaseous Discs of Early Evolved Protostars"], "Total_Cost": ["EUR 187 866"], "Country": ["Ireland"], "Project_ACR": ["DIGDEEP"], "Technology_Description": "A first step towards understanding planetary formation is the characterisation of the structure and evolution of protoplanetary discs. Although the large scale disc is understood in some detail, very little is known about the inner 5 au (i.e. within a radius corresponding to Jupiter's orbit) in which the main physical processes take place: accretion, ejection and planetary formation. For the nearest sites of star formation, this region is inaccessible to standalone telescopes, and only recently optical/infrared interferometers have been able for the first time to spatially resolve it. ", "To": ["2018-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-11-01"], "Project_ID": ["706320"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["STIFTUNG PREUSSISCHER KULTURBESITZ", "STIFTUNG PREUSSISCHER KULTURBESITZ"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Localizing 4000 Years of Cultural History. Texts and Scripts from Elephantine Island in Egypt"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["ELEPHANTINE"], "Technology_Description": "The aim of this project is to write a cultural history of 4000 years, localized on Elephantine Island in Egypt. Elephantine was a militarily and strategically very important island in the river Nile on the southern border of Egypt. No other settlement in Egypt is so well attested over such a long period of time. Its inhabitants form a multi-ethnic, multicultural and multi-religious community that left us vast amounts of written sources detailing their everyday lives from the Old Kingdom to beyond the Arab Conquest. Today, several thousand papyri and other manuscripts from Elephantine are scattered in more than 60 institutions across Europe and beyond. Their texts are written in different languages and scripts, including Hieroglyphs, Hieratic, Demotic, Aramaic, Greek, Coptic and Arabic. 80% of these manuscripts are still unpublished and unstudied. The great challenge of this project is to use this material to answer three key questions covering:", "To": ["2020-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2015-07-01"], "Project_ID": ["637692"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["INSTITUT CURIE", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSITY OF KEELE", "UNIVERSITAET OSNABRUECK", "RUHR-UNIVERSITAET BOCHUM", "EFFICIENT INNOVATION SAS"], "EU_Contribution": ["EUR 3 473 026"], "Project_Title": ["Hijacking cell signalling pathways with magnetic nanoactuators for remote-controlled stemcell therapies of neurodegenerative disorders"], "Total_Cost": ["EUR 3 473 026"], "Country": ["France", "France", "United Kingdom", "Germany", "Germany", "France"], "Project_ACR": ["MAGNEURON"], "Technology_Description": "Neurodegenerative diseases, such as Parkinson\u2019s disease, are a major public health issue given the aging population in Europe and beyond. While curative pharmacological treatment of these diseases is not in sight, cell replacement therapies (CTs) are considered very promising, in particular with the advent of stem-cell reprogramming technologies. However, a fundamental challenge in the medical application of CTs in the brain of patients lies in the lack of control of cell behaviour at the site of transplantation, and particularly their differentiation and oriented growth. The aim of this project is to introduce a fundamentally new concept for remote control of cellular functions by means of magnetic manipulation. The technology is based on magnetic nanoparticles functionalized with proteins involved in cellular signalling cascades. These biofunctionalized MNPs (bMNPs) will be delivered into target cells, where they act as intracellular signalling platforms activatable in a spatially and temporally controlled manner by external magnetic fields. The project will focus on engineering these tools for the control of neuronal cell programming and fibre outgrowth by hijacking Wnt and neurotrophin signalling, respectively, with the ulti-mate objective of advancing cell replacement therapies for PD using dopaminergic precursor neurons.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-1-2014 - FET-Open research projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-01-01"], "Project_ID": ["686841"], "Call_for_Proposal": ["H2020-FETOPEN-2014-2015-RIA"]}, -{"Partners": ["THE ROYAL VETERINARY COLLEGE"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Harnessing the power of bioinformatic analysis to improve genetic selection for fertility in dairy cows"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["Bioinformatics4Breeding"], "Technology_Description": "Genetic selection for high yielding dairy cows has been associated with reduced fertility. Infertility remains the major reason for culling, decreasing longevity and reducing production efficiency. We propose that this trend could be reversed by identifying key genes involving reproductive function and selective breeding of more longlasting cows. The specific research objectives are: 1) to train the incoming researcher in bioinformatics methodologies related to analysis of large genomic datasets including SNP detection, genotyping, and evolutionary conserved DNA elements detection; 2) to use the methodologies to analyse dairy phenotypic and genomic data to highlight potential genic and regulatory regions of the cattle genome containing polymorphisms which are beneficial, with a particular focus on fertility; 3) to use appropriate tools to investigate the likely effects of both coding and regulatory variants on the expression of the candidate genes found in these regions; 4) to use pathway analysis to understand how the candidate genes may influence key molecular events and larger gene networks involved in reproductive phenotypes; 5) to recommend appropriate selection procedures to the EU dairy breeding industry to supplement current genomic methods. The project combines the expertise of Consiglio per la Ricerca in Agricoltura e l\u2019analisi dell\u2019Economia agraria, Italy (CREA) and the Royal Veterinary College, UK (RVC) in farm animal genetics and genomics and dairy cow production. The objectives will be met by the mobility of Dr L Buggiotti to the UK, where she will work closely alongside two senior RVC scientists, Dr DM Larkin and Professor DC Wathes. She will transfer this expertise back to CREA on her return. Both groups are experienced in knowledge transfer to the dairy industry and are committed to use the information generated to breed more fertile cows, so improving longevity and promoting sustainability of the EU dairy industry.", "To": ["2018-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["703376"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITEIT MAASTRICHT"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["microRNAs in susceptibility to traumatic stress"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["TraumiR"], "Technology_Description": "Traumatic stressors are important and prevalent risk factors for psychiatric disorders, such as post-traumatic stress disorder (PTSD). People differ strikingly in their susceptibility to develop PTSD after traumatic stress, however the exact underlying biological mechanisms of differential susceptibility are unknown. The identification of biomarkers that distinguish between persons at high and low risk of developing PTSD following trauma exposure would enable more effective preventive strategies and early interventions. Epigenetic mechanisms have been proposed to underlie the relationship between exposure to traumatic stress and the susceptibility to develop PTSD. Recent work carried out by the host laboratory demonstrated that DNA methylation might regulate the impact of traumatic stress on gene expression and ultimately brain function. Based on this and the emerging role of miRNA as key epigenetic players in psychiatric disorders, I hypothesize that (i) susceptibility to traumatic stress exposure is associated with distinct miRNAs expression profiles with blood-brain correlation, (ii) experimental manipulation of miRNA expression levels in animals alters their susceptibility to traumatic stress. These hypotheses will be tested by a unique set of epigenetic epidemiological studies using prospective cohorts with longitudinal sampling schemes of military soldiers deployed to war, next to experimental animal studies. The proposed multidisciplinary and translational project will open the possibility of tapping into the mechanisms underlying differential susceptibility to traumatic stress through blood profiling. It has excellent prospects for yielding clinically relevant and usable biomarkers for the prediction of susceptibility to traumatic stressors. Moreover, the project will reinforce my foundation as a highly promising early career researcher by broadening my knowledge, skills, professional experience and network necessary to launch my own research group.", "To": ["2018-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["707362"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITY OF KENT"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Human myosins"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["FCSM"], "Technology_Description": "In utero development is critical for normal skeletal and cardiac muscle function throughout life. Many diseases, such as distal arthrogryposis (affecting 1/3000 live births) and clubfoot (1/1000) in skeletal muscle and arrhythmias in cardiac muscle (1/4000), manifest in the embryonic and foetal period. They permanently affect longevity and quality of life. Because the effects of these diseases are present at birth, the study of in utero samples is essential to understanding the diseases\u2019 properties and effects on the developing muscle tissues. Additionally, many of these afflictions are caused by mutations in the isoforms of troponin or myosin II that are predominantly expressed during human development. Studying the native muscle is all the more important as a control in furthering research on the effects of mutations in troponin and myosin. In particular, human foetal-specific isoforms of myosin II expressed in these muscle are poorly understood and very little has been published about these isoforms. We do know from the literature that myosin\u2019s use of its substrate, ATP, varies widely between isoforms and that the myosin expression changes during times of physiological distress, such as heart failure. Because congenital abnormalities of the heart and skeletal muscle both can originate in the foetal muscle, further investigation is needed into the myosins\u2019 biophysical and biomechanical mechanisms. The overarching goal of this project is to improve understanding of how foetal forms of skeletal and cardiac myosins work and are regulated by troponin in muscle, using biophysical-biochemical, molecular biology and computational modelling techniques. The fellow will do this by experimentally determining the kinetics of myosin-ATP, myosin-actin and myosin-actin-troponin-tropomyosin interactions using stopped-flow kinetic analysis, and then use the parameters defined to inform the computational models developed by Dr. Geeves.", "To": ["2017-05-31, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-06-01"], "Project_ID": ["659534"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE ROYAL VETERINARY COLLEGE"], "EU_Contribution": ["EUR 251 857,80"], "Project_Title": ["Network Analysis of Musculoskeletal Evolution and Modularity during the Fin-to-Limb Transition"], "Total_Cost": ["EUR 251 857,80"], "Country": ["United Kingdom"], "Project_ACR": ["LIMB NETWORKS"], "Technology_Description": "The fin-to-limb transition was a major milestone in the history of life that shaped the morphology and remarkable biodiversity of land vertebrates. A central question in vertebrate evolution is how the various anatomical parts of limbs evolved semi-autonomously (modularity) while still growing and adapting in coordination (integration). The main goal of this project is to unravel (i) the evolutionary changes in modularity of the musculoskeletal system that occurred during the evolution from fins to limbs and (ii) how these newly acquired modular organizations facilitated the evolution of different morphologies for the forelimb and hindlimb. To this end, we will evaluate the modularity of limbs and the strength of topological integration among modules by using an innovative approach\u2013anatomical network analysis\u2013\u00ac\u00acbased on the topological relations that anatomical parts establish among them; these anatomical relations are embodied in network models and quantified globally using sophisticated algorithms from Graph Theory. We propose a multidisciplinary combination, for the first time, of (i) new data on fin/limb muscle anatomy in extant species, (ii) reconstruction of muscle attachments in extinct forms, and (iii) the use of innovative tools such as Anatomical Network Analysis to identify morphological modules and quantify their integration within a phylogenetic context. The results of this unique and transformative project have the potential to revolutionize our understanding of limb evolution during the fin-limb transition. The training in gross anatomy, imaging techniques, and reconstruction of muscles in fossils by the leading researchers involved in this project will foster the development of the candidate Fellow as an independent and innovative frontline researcher in theoretical, evolutionary, and comparative biology in the EU.", "To": ["2018-08-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-08-15"], "Project_ID": ["654155"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITEIT MAASTRICHT"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["Enhancing expectancy formation in healthy aging through statistical and sensorimotor learning"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["Expectancy learning"], "Technology_Description": "My research examines how humans form new expectancies, or states of anticipation for future events, and how expectancy formation changes over the lifespan. Humans constantly anticipate upcoming events in order to understand those events, prepare actions, and adapt to changes. Although the neural and behavioral signatures of expectancies have been well-characterized, we do not know how they arise and how they change over the lifespan. I aim to reveal the following: 1) How new expectancies are formed during the course of learning novel information. 2) How expectancy formation differs between younger and older adults. 3) How the combination of regularities in event structure and sensorimotor integration, a phenomenon that has not been investigated, potentiates expectancy formation. 4) The role of interacting subcortical-cortical neural networks in expectancy formation. I will monitor the dynamic changes in electrophysiological brain responses, as well as overt anticipatory behaviour, over the course of learning in order to capture the changes of anticipatory responses online, and I will apply Bayesian neural network modelling to infer the neural and cognitive state changes underlying these response changes. I will also measure changes in subcortical-cortical networks that result from learning, including structural integrity, functional connectivity, and the ability to decode the learned information. This multi-methods approach will utilize my expertise in behavioural and MRI methods combined with my research group's expertise in EEG and computational modelling, as well as the state-of-the-art EEG, MRI, and laboratory facilities, on-site expertise, and support staff available at Maastricht University. This research is urgently needed so that we can finally understand the origin of expectancies, their consequences on the aging brain, and how we can enhance their formation to improve lifelong learning.", "To": ["2018-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["707865"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["ACADEMISCH ZIEKENHUIS GRONINGEN"], "EU_Contribution": ["EUR 196 380,90"], "Project_Title": ["Moving from genome wide association to elucidating causal mechanisms of electrocardiographic traits"], "Total_Cost": ["EUR 196 380,90"], "Country": ["Netherlands"], "Project_ACR": ["MOvE-ECG"], "Technology_Description": "Understanding how genes and genetic variants influence heart function is of major importance, not only from a basic science viewpoint, but also as a foundation for future innovation in medicine and health-care. In this proposal, Dr. Niek Verweij aims to identify novel genes and mechanisms underlying heart growth. This will be done in collaboration with the top-scientist Dr. Chris Newton-Cheh (Harvard/Massachusetts General Hospital, Broad Institute of Harvard and MIT) and Dr. Laurie Boyer (MIT). As heart growth accompanies many forms of heart disease, this project will focus on the QRS-complex (of the electrocardiogram) in population based studies as this reflects electrically active cardiac mass. We will search for novel low-frequency genetic variants associated with the QRS-complex within the CHARGE consortium and within a Dutch population using dedicated reference panels. Loci will be interrogated through the use of published and unpublished in silico big-data sets to further prioritize variants and regions for experimental follow-up aimed at elucidating biological mechanisms. This project will bridge the gap between population based genetic association studies (with Dr. Newton-Cheh) to functional biology (with Dr. Laurie Boyer). This proposal will provide novel insights into cardiomyocyte functioning and provide novel avenues to study heart disease vulnerability and design innovative treatment.", "To": ["2017-09-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-07-01"], "Project_ID": ["661395"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITY OF STRATHCLYDE", "The Mental Health Foundation", "SUOMEN MIELENTERVEYSSEURA RY", "UNIVERSITAET ULM"], "EU_Contribution": ["EUR 477 000"], "Project_Title": ["Citizenship, Recovery and Inclusive Society Partnership"], "Total_Cost": ["EUR 477 000"], "Country": ["United Kingdom", "United Kingdom", "Finland", "Germany"], "Project_ACR": ["CRISP"], "Technology_Description": "People with mental health problems experience significant inequalities including high levels of early mortality, morbidity, unemployment, poverty, isolation and social exclusion. This also presents major health, social and economic challenges to wider society. Our International Network unites leaders from academia, policy, practice, business and community organisations from the EU and US. Each partner has an impressive track record of leading evidence-based policy and programme development at a national level and each has pioneered participation in research of people with lived experience of mental health problems. This transatlantic network will share and build upon state of the art knowledge in four key areas of social inclusion: citizenship, recovery, stigma and public policy. Our collaboration will enable new knowledge, synergies and solutions to emerge by connecting our diverse national and disciplinary perspectives with the lived experiences of people with mental health problems. Through the network we will enhance the skills and career opportunities for researchers and practitioners, and contribute towards the sustained inclusion of people with lived experience. This grant will enable us to share our learning in profound ways to understand \u2018what works\u2019 in very different social contexts, including through interaction between the four themed work packages. There is a strong commitment amongst partners to maintain the network long term. As partners we have considerable experience in supporting participatory mental health research with migrant citizens, people who are homeless and diverse ethnic minorities. Social exclusion is often intensified for women who encounter gender-based discrimination and cumulative adversity. Therefore, throughout this proposal, we will pay particular attention to issues of intersectionality in relation to gender, and consider how promoting social inclusion, citizenship and rights must take account of social identities.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Other", "Other", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["690954"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "UNIVERSITAETSKLINIKUM ESSEN", "UNIVERSITEIT MAASTRICHT", "TECHNISCHE UNIVERSITAET DRESDEN", "UNIVERSITE CATHOLIQUE DE LOUVAIN", "INSTITUT CURIE"], "EU_Contribution": ["EUR 3 081 061,44"], "Project_Title": ["Radiation Innovations for Therapy and Education"], "Total_Cost": ["EUR 3 081 061,44"], "Country": ["United Kingdom", "Germany", "Netherlands", "Germany", "Belgium", "France"], "Project_ACR": ["RADIATE"], "Technology_Description": "Approximately 45-60% of all cancer patients are treated with radiotherapy. Some of these patients have a good outcome, but in other cases their illness fails to be cured. This may result from distant metastases or from regrowth of the primary tumor. This training network is built on the premise that considerable advances in understanding radiobiology will open novel routes for effective therapeutic intervention with biological targets to improve the outcome of cancer treatment; this progress requires a European-wide effort. ", "To": ["2019-02-28, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2015-03-01"], "Project_ID": ["642623"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["UNIVERSITEIT MAASTRICHT"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["Monitoring changes in brain states using dynamical causal networks"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["DynamicBrainStates"], "Technology_Description": "I propose a new model and estimation method that will allow Neuroscientists to detect, track, and predict temporal changes in dynamical brain networks non-invasively. These changes underpin shifts in brain (cognitive) states which are currently inaccessible using standard Neuroimaging techniques. The method combines recent advances in dynamical systems theory and Bayesian inference to integrate Electroencephalography (EEG) and Diffusion Weighted Magnetic Resonance Imaging (DWMRI) data in an efficient way. I will provide a proof of concept that the method can be used as a tool for early diagnosis of brain dysfunction. Given the current emphasis on reducing the social and economic impact of neurodegeneration and aging across the EU, I focus on using Transcranial Magnetic Stimulation (TMS) to induce small changes in two exemplars of distributed networks that simulate semantic and motor neurodegeneration as a demonstration of what this method can detect. The proposed approach has the potential to change strategies for screening and early diagnosis of neurodegenerative conditions. It will lead to new clinical applications that will significantly impact the study of the aging brain and mental health, as well as the analysis of a wide variety of normal brain function, such as social behaviour, decision-making, or resting-state.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["703211"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITE DES SCIENCES ET TECHNOLOGIES DE LILLE - LILLE I", "RUHR-UNIVERSITAET BOCHUM", "UNIVERSITATSKLINIKUM ERLANGEN", "GOETEBORGS UNIVERSITET", "LVIVSKYI NATIONALNYI MEDYCHNYI UNIVERSYTET IMENI DANYLA HALYTSKOHO", "GRAPHENEA SA", "LSO MEDICAL", "RS ARASTIRMA EGITIM DANISMANLIK ILAC SANAYI TICARET LIMITED SIRKETI"], "EU_Contribution": ["EUR 580 500"], "Project_Title": ["Pathogen and Graphene"], "Total_Cost": ["EUR 580 500"], "Country": ["France", "Germany", "Germany", "Sweden", "Ukraine", "Spain", "France", "Turkey"], "Project_ACR": ["PANG"], "Technology_Description": "Complications related to infectious diseases have significantly reduced, particularly in the developed countries, due to the availability and use of broad-range antibiotics and wide variety of antimicrobial agents. Excessive use of antibiotics and antimicrobial agents increased significantly the number of multi-drug resistant (MDR) bacteria. This has resulted in a serious threat to public health. The inexorable rise in the incidence of antibiotic resistance in bacterial pathogens, coupled with the low rate of emergence of new clinically useful antibiotics, has refocused attention on finding alternatives to overcome antimicrobial resistance. Novel strategies aiming to reduce the amount of antibiotics, but able to prevent and treat animal and human infections should be investigated, evidenced and approved. Among the various approaches, the use of graphene and its derivatives is currently considered a highly promising strategy to overcome microbial drug resistance.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-01-01"], "Project_ID": ["690836"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "UNIVERSITAET BIELEFELD", "ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOMATERIALES- CIC biomaGUNE", "DIOMUNE SL", "KEMIJSKI INSTITUT", "ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOCIENCIAS", "VIB", "LOFARMA S.P.A.", "UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II."], "EU_Contribution": ["EUR 3 122 539,38"], "Project_Title": ["Toll-Like Receptor 4 activation and function in diseases: an integrated chemical-biology approach."], "Total_Cost": ["EUR 3 122 539,38"], "Country": ["Italy", "Spain", "Germany", "Spain", "Spain", "Slovenia", "Spain", "Belgium", "Italy", "Italy"], "Project_ACR": ["TOLLerant"], "Technology_Description": "Based on an international team derived from the COST action BM1003 (www.cost-bm1003.info, 2011-2014) and thus relying on consolidated group interactions and synergies and on a unique combination of chemistry, biology, biophysics, biochemistry and pharmacology expertise, the TOLLerant project aims to gain information on molecular aspects of TLR4 activation and signaling by using synthetic and natural compounds and nanoparticles that interact selectively with some components (mainly MD-2 and CD14) of the TRL4 recognition system. ", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2015-01-01"], "Project_ID": ["642157"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["UNIVERSITEIT MAASTRICHT"], "EU_Contribution": ["EUR 260 929,80"], "Project_Title": ["Chinese Heritage Tours and Adoptive Origin Stories: Towards a Transnational Adoptive Field"], "Total_Cost": ["EUR 260 929,80"], "Country": ["Netherlands"], "Project_ACR": ["OriginStories"], "Technology_Description": "China became the largest source of adopted children worldwide since its Transnational Adoption Program in 1992.As adoptees are coming of age, some are interested in exploring their roots. Concurrently, as international adoptions come under the scrutiny of critical groups in sending and receiving countries, heritage tours have become a popular way to satisfy the needs of different actors involved: from adoptive families seeking the youths\u2019 roots to economically minded tour operators and adoption agencies, to critical Western-based civil society groups who advocate psychological benefits for adoptees, such a resolution to their emotional befuddlement. Heritage tours are thus where transnational kinning practices are played out, different notions of belonging intersect, and broader state and organizational interests meet. Thus, these tours constitute the ideal case for studying the transnational family-making process from a truly transnational perspective. Through a detailed comparative study of how adopters and adoptees in Spain and the US-the countries with the largest number of Chinese adoptees-Chinese first parents, and Chinese and Western heritage tour agencies negotiate their different interests, my research will facilitate one of the first multi-sited and multi-actor perspectives on transnational kinning practices through transnational adoption. The study brings together recent literature on transnational families and transnational adoption and uses mixed methods from the social sciences and humanities to build a Transnational Adoptive Field approach intended to provide a comprehensive and cross-country comparative way to study transnational adoptive family-making processes and involves ethnographic fieldwork in three different countries, interviews with key stakeholders and narrative analysis. In a wider sense, this inquiry is a case through which we may scrutinize the shifting meanings that re-define familial and national belonging in today\u2019s globalizing world", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["660776"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["CITY UNIVERSITY OF LONDON", "Biologicke centrum AV CR, v. v. i.", "EOTVOS LORAND TUDOMANYEGYETEM", "UNIVERSITA DEGLI STUDI DI TORINO", "UNIVERSITEIT MAASTRICHT"], "EU_Contribution": ["EUR 216 000"], "Project_Title": ["Conflict, Competition, Cooperation and Complexity: Using Evolutionary Game Theory to model realistic populations"], "Total_Cost": ["EUR 243 000"], "Country": ["United Kingdom", "Czech Republic", "Hungary", "Italy", "Netherlands"], "Project_ACR": ["FourCmodelling"], "Technology_Description": "\"Real animals and human populations are complex, involving structural relationships depending upon space and time and varied interactions between potentially many individuals. Human societies feature family units, communities, companies and nations. Some animal also have complex societies, such as primate groups and social insect colonies. Single organisms themselves can be thought of as complex ecosystems, host to many interacting life forms. ", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["690817"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["HELMHOLTZ-ZENTRUM FUER INFEKTIONSFORSCHUNG GMBH", "KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW"], "EU_Contribution": ["EUR 333 000"], "Project_Title": ["Golden Mycological Triangle \u2013 joining forces to exploit mycological biodiversity for novel anti-infectives and other beneficial metabolites"], "Total_Cost": ["EUR 333 000"], "Country": ["Germany", "Netherlands"], "Project_ACR": ["GoMyTri"], "Technology_Description": "The proposed project aims at the intensification of cooperations between research infrastructure organisations in German, the Netherlands and Thailand that are recognised internationally as strongholds in mycological, biotechnological and microbiological research. The cooperation is intended to explore the mycological and microbiological biodiversity of Europe and Southeast Asia, in particular with regard to the search for the badly needed new antibiotics and other biologically active substances. ", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2015-01-01"], "Project_ID": ["645701"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["RUHR-UNIVERSITAET BOCHUM"], "EU_Contribution": ["EUR 128 595,60"], "Project_Title": ["Improving wet plastic recycling through innovative lagrangian particle-fluid simulations"], "Total_Cost": ["EUR 128 595,60"], "Country": ["Germany"], "Project_ACR": ["IMPRECSIM"], "Technology_Description": "Wet particle separation is used widely in mineral processing as well as plastic recycling to separate mixtures of particulate materials into further usable fractions due to density differences. Despite its wide usage wet particle separation processes are often attributed to operational problems especially if density differences of the feed material are low. A review of the state of the art clearly indicates that numerical modelling has not yet been applied to wet separation processes due to the lack of applicable numerical schemes. On this background numerical modelling can strongly contribute towards improving the design and process parameters of wet particle separation technologies especially in the field of plastic recycling - improvements have a strong environmental impact such as reduced landfill and lower overall pollution.", "To": ["2016-11-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-06-01"], "Project_ID": ["652862"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["CONSORCI INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER"], "EU_Contribution": ["EUR 1 062 000"], "Project_Title": ["Biomedicine international training research programme for excellent clinician-scientists"], "Total_Cost": ["EUR 2 124 000"], "Country": ["Spain"], "Project_ACR": ["BITRECS"], "Technology_Description": "Significant advances in clinical practice cannot be made without a thorough understanding of the disease mechanisms from laboratory benches combined with good clinical observation and knowledge of disease management from the bed side.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2016 - Co-funding of regional, national and international programmes"], "Funding_scheme": ["MSCA-COFUND-FP - Fellowship programmes"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-10-01"], "Project_ID": ["754550"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2016"]}, -{"Partners": ["UNIVERSIDAD DE ALCALA"], "EU_Contribution": ["EUR 2 407 200"], "Project_Title": ["GOT ENERGY TALENT. Attracting Talented Researchers within the Spanish Campus of International Excellence \u2018Smart Energy\u2019 and the region of Madrid."], "Total_Cost": ["EUR 4 814 400"], "Country": ["Spain"], "Project_ACR": ["GOT ENERGY"], "Technology_Description": "GOT ENERGY TALENT is a highly competitive, merit-based fellowship programme aimed at incorporating postdoctoral talent on the area of SMART ENERGY to enable them to conduct their own excellent research project and bringing it closer to the society, in order to produce a positive effect not only in terms of excellent science and talent attraction but also by strengthening the regional economy and promoting international networking.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2016 - Co-funding of regional, national and international programmes"], "Funding_scheme": ["MSCA-COFUND-FP - Fellowship programmes"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["754382"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2016"]}, -{"Partners": ["FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA"], "EU_Contribution": ["EUR 3 398 400"], "Project_Title": ["MultIscale precision therapies for NeuroDEvelopmental Disorders"], "Total_Cost": ["EUR 6 796 800"], "Country": ["Italy"], "Project_ACR": ["MINDED"], "Technology_Description": "Neurodevelopmental disorders (NDD) represent an enormous burden for patients, their families, and society. Within EU, the incidence of autism spectrum disorders (ASD) is increasing to over 100 per 10,000 individuals. By comparison, new cases of brain cancers in EU are estimated to be 10 per 10,000. Also, the requirement for lifelong care has a dramatic impact on healthcare costs, with an average lifelong cost per ASD patient of ~ 3.0 MEuro. ", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2016 - Co-funding of regional, national and international programmes"], "Funding_scheme": ["MSCA-COFUND-FP - Fellowship programmes"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Chiara Andreoli", "Tel.: +3901071781854", "Fax: +39 010 7170817"], "From": ["2018-01-01"], "Project_ID": ["754490"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2016"]}, -{"Partners": ["RUHR-UNIVERSITAET BOCHUM", "KATHOLIEKE UNIVERSITEIT LEUVEN", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSITEIT UTRECHT", "UNIVERSITEIT GENT", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "RUBOTHERM GMBH", "Scientific Computing & Modelling N.V.", "TECHNISCHE UNIVERSITAET MUENCHEN", "TECHNISCHE UNIVERSITAET BERGAKADEMIE FREIBERG"], "EU_Contribution": ["EUR 3 804 639,48"], "Project_Title": ["DEFect NETwork materials science and engineering"], "Total_Cost": ["EUR 3 804 639,48"], "Country": ["Germany", "Belgium", "Spain", "France", "Netherlands", "Belgium", "United Kingdom", "Germany", "Netherlands", "Germany", "Germany"], "Project_ACR": ["DEFNET"], "Technology_Description": "Porous coordination network materials, also known as Metal-organic Frameworks (MOFs), are at the cutting edge of molecular materials science. DEFNET, \u201cDEFect NETwork materials science and engineering\u201d, is the first European Training Network (ETN) at the intersection of chemistry, physics and engineering aimed at structural and functional complexity of MOFs. It provides a unique interdisciplinary training platform for early stage researchers and combines the expertise of the academic and the non-academic sector for fundamental development and industrial application and technology transfer aspects. The research and the training program in materials synthesis, characterization, computational modelling and application is accomplished in a coordinated effort involving 8 academic and 8 industrial partners from 6 European countries. DEFNET will particularly investigate defects, disorder and correlated phenomena in MOFs and related materials. The understanding and the intentional modification of defect structures of porous coordination networks is essential for advanced controlling their properties in catalysis, gas capture and separation beyond existing materials limitations. Benchmarking will be done against selected zeolite materials, which are very well established for large scale industrial applications. It is anticipated that superior functionalities of defect engineered MOFs will be identified which cannot be achieved by employing other porous materials.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-01-01"], "Project_ID": ["641887"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE"], "EU_Contribution": ["EUR 3 767 040"], "Project_Title": ["The launch of a new industrial PhD programme at EPFL"], "Total_Cost": ["EUR 7 534 080"], "Country": ["Switzerland"], "Project_ACR": ["EPFLinnovators"], "Technology_Description": "The \u201cE\u0301cole Polytechnique Fe\u0301de\u0301rale de Lausanne\u201d (EPFL) is one of the two Federal Institutes of Technology in Switzerland. EPFL has three missions: i) education, ii) research, and iii) technology transfer. The EPFL is successful in fulfilling these missions, and is ranked as one of Europe\u2019s top institutions with respect to education, research, training-through-research and innovation.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2016 - Co-funding of regional, national and international programmes"], "Funding_scheme": ["MSCA-COFUND-DP - Doctoral programmes"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["754354"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2016"]}, -{"Partners": ["EIDGENOSSISCHE MATERIALPRUFUNGS- UND FORSCHUNGSANSTALT"], "EU_Contribution": ["EUR 3 540 000"], "Project_Title": ["EMPAPOSTDOCS-II MSCA COFUND International, interdisciplinary, inter-sectoral PostDoc Fellowship Programme at Empa"], "Total_Cost": ["EUR 7 080 000"], "Country": ["Switzerland"], "Project_ACR": ["EMPAPOSTDOCS-II"], "Technology_Description": "After successfully applying for a first postdoctoral fellowship programme in 2010, Empa has decided to create a second fellowship programme: It will allow 50 experienced researchers from all over the world to create a research project and get the opportunity to work on their own research idea at one of the 30 research laboratories of Empa, in cooperation with a senior scientist of Empa of his/her choice. The training and mentoring scheme will ensure that the fellows not only enhance their scientific experience but also acquire key long-life skills making them \u201ccontributing players\u201d of the research community and society in general. As an interdisciplinary research institution within the Swiss ETH Domain, Empa, the Swiss Federal Laboratories for Materials Science and Technology, conducts cutting-edge materials and technology research. Empa\u2019s activities focus on meeting the requirements of industry and the needs of society, and thus link applications-oriented research to the practical implementation of new ideas in the areas of nanostructured, \u201csmart\u201d materials and surfaces, environmental, energy and sustainable building technologies as well as biotechnology and medical technology.", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2016 - Co-funding of regional, national and international programmes"], "Funding_scheme": ["MSCA-COFUND-FP - Fellowship programmes"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["754364"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2016"]}, -{"Partners": ["RIJKSUNIVERSITEIT GRONINGEN"], "EU_Contribution": ["EUR 1 046 400"], "Project_Title": ["Data Science and Systems Complexity Research Training Programme"], "Total_Cost": ["EUR 2 092 800"], "Country": ["Netherlands"], "Project_ACR": ["DSSC"], "Technology_Description": "Today\u2019s world is a highly complex system that is producing massive amounts of data daily. We can only progress towards urgent global priorities such as sustainable energy, personalized healthcare or the development of the data-driven economy if we can predict the dynamic nature of such a system. This challenge calls for an integrated approach that uses data to understand the behaviour of complex systems, and for experts who can handle data and complexity problems for society at large. ", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2016 - Co-funding of regional, national and international programmes"], "Funding_scheme": ["MSCA-COFUND-DP - Doctoral programmes"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["754315"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2016"]}, -{"Partners": ["UNIVERSITAT AUTONOMA DE BARCELONA"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Generalized geometry: 3-manifolds and applications"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["GENERALIZED"], "Technology_Description": "Generalized geometry is a revolutionary approach to geometric structures pioneered by Hitchin in 2003, soon becoming an active topic catching the interest and bringing together the expertise of geometers and theoretical physicists. Generalized complex structures, defined for even-dimensional manifolds, are both a genuinely interesting mathematical structure, providing insight of complex and symplectic geometry, and the suitable notion for some physical theories like mirror symmetry. Odd-dimensional manifolds within generalized geometry have not been satisfactorily studied until the recent introduction of generalized geometry of type Bn and its study in my PhD thesis. There, the case of 3-manifolds drew special attention thanks to the recent Thurston's geometrization theorem and the fact that the type-change locus of a 3-manifold is a link, bringing in knot and link theory. This action combines the generalized geometry expertise of the experienced researcher with the host\u2019s expertise on 3-manifold and knot and link theory in order to set a novel geometrical framework for structures on odd-dimensional manifolds, understand the case of 3-manifolds in depth, and create a two-way bridge between these previously unrelated areas, with innovative applications in both.", "To": ["2020-04-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-05-01"], "Project_ID": ["750885"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Enabling Visual IoT Applications with Advanced Network Coding Algorithms"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ENVISION"], "Technology_Description": "The latest advances and integration of several key technologies such as wireless communications, low-power sensing, embedded systems, Internet protocols and cloud computing, have enabled the emergence of the Internet of Things (IoT) paradigm. However, the ever-growing deployment of the visual sensing applications within IoT deployments is expected to strain the network and cloud infrastructures used to deliver and store massive amounts of visual data. To partly address these challenges, prototypes of neuromorphic visual sensors, a.k.a. dynamic vision sensors (DVS), have been produced in the last two years. Instead of the conventional raster scan of video cameras, DVS devices record pixel coordinates and timestamps of reflectance events in an asynchronous manner, thereby offering substantial improvements in sampling speed and power consumption. ENVISION argues that, in order to fully exploit the advantages of neuromorphic sensing for IoT applications, such devices should be coupled with appropriate transmission and storage mechanisms that would take advantage of the visual data properties to achieve even higher bandwidth, power and storage efficiency. The ENVISION project aims at developing such data-driven delivery and storage algorithms based on advanced network coding techniques for data acquired by both conventional frame-based video cameras and DVS devices. Specifically, ENVISION is pursuing three interconnected research objectives: (i) designing advanced content-driven network codes for efficient transmission of the visual content captured by neuromorphic and conventional visual sensors to the cloud service under bandwidth and power constraints, (ii) developing novel content-aware network codes for storage of the visual content under the cost-performance optimisation framework, and (iii) investigating approximate decoding techniques including both the theoretical analysis of the performance and the implementation of practical low-complexity decoders.", "To": ["2020-01-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-15"], "Project_ID": ["750254"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["HERIOT-WATT UNIVERSITY"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Novel braced frame for earthquake resilience"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["CBF-EQRES"], "Technology_Description": "The project will develop a seismic-resistant steel frame for high seismic resilience. The frame consists of a moment-resisting frame equipped with concentric braces. Replaceable energy-dissipative hourglass shape pins made of duplex stainless steel that results in high post-yield stiffness are in series connected to the braces. Moreover, replaceable fuses are introduced at the locations of the beams of the moment resisting frame where plastic hinges are expected to develop. The project uses an integrated experimental-numerical research methodology to evaluate the seismic performance of the proposed configuration. Emphasis is placed in developing a reliable seismic design methodology for the practical application of the proposed system.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["748328"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA"], "EU_Contribution": ["EUR 168 277,20"], "Project_Title": ["Electromyography-driven musculoskeletal modelling for biomimetic myoelectric control of prostheses with variable stiffness actuators"], "Total_Cost": ["EUR 168 277,20"], "Country": ["Italy"], "Project_ACR": ["MIMICS"], "Technology_Description": "Upper limb loss affects 94.000 individuals in Europe. Advanced treatments rely on myoelectric prostheses controlled by amputees\u2019 electromyograms or EMG. Despite expected benefits, today's schemes provide limited re-gain of functionality and lack of bio-mimesis, i.e. they use: (1) direct mapping between EMG and prosthesis joint angle, disregarding underlying neuromusculoskeletal processes, and failing to generalize to unseen conditions (robustness lack), (2) stiff actuators not mimicking biological compliant joints, preventing natural motion (functionality lack). MIMICS proposes a biomimetic paradigm: (1) a modelling formulation that simulates amputee\u2019s phantom limb musculoskeletal dynamics as controlled by EMGs, and (2) prostheses with variable stiffness \u201csoft\u201d actuators. This opens to next-generation \u201csoft\u201d prostheses that can mimic biological limb functionality and robustness; a priority of current European policies and technology roadmaps, with estimated initial markets for functional myoelectric prostheses of \u20ac1 billion. MIMICS combines required interdisciplinary skills on soft actuation (host), neuromusculoskeletal modelling (fellow), and clinical bionic reconstruction (secondment). The career development plan is tailored on fellow\u2019s needs: new skills acquisition (soft actuation/clinical prosthetics), project/teamwork management, open science/gender aspects care, ERC grant writing support. The action transfers fellow\u2019s pre-acquired knowledge to the host and opens cooperation with secondment institute, thus increasing host\u2019s visibility in myoelectric control and clinical prosthetics. The secondment expands MIMICS outcomes to boarder clinical perspectives and boosts knowledge transfer among organizations. Outreach activities plan to improve public understanding of MIMICS achievements, socio-economical potentials and clinical benefits. This all is set to improve fellow\u2019s career prospects and form a European network of excellence in neurorehabilitation technologies", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Chiara Andreoli", "Tel.: +3901071781854", "Fax: +39 010 7170817"], "From": ["2018-09-01"], "Project_ID": ["747045"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["GENOTYPE - ENDOPHENOTYPE ASSOCIATIONS IN PSYCHOSIS"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["GENDOSIS"], "Technology_Description": "Psychotic disorders impose an increasing burden on the health of the European population, with an estimated five million affected individuals. As available drugs remain ineffective for 30% of the patients and come with many secondary effects, there is urgent need to develop effective and safe therapeutic agents. Due to the high heritability of psychotic disorders, genetics shows great potential to inform the molecular mechanisms behind their pathogenesis. However, the information we have gathered on psychosis genetics has not translated into improved therapeutics yet, due to, among other reasons, two big limitations: poor knowledge of the mechanisms behind the genetics \u2013 psychosis relation and high levels of heterogeneity at the molecular level in the patient population. The research program we present aims at relieving the burden of these limitations using a genotype \u2013 endophenotype mapping strategy to shed light on disease mechanisms and identify genetic variants to be used in a patient-stratification analysis. Using a large dataset of psychosis patients, unaffected relatives and unrelated controls with genotypic and endophenotypic data we will perform a comprehensive genotype \u2013 endophenotype mapping through genome-wide linkage and association analyses. The results of the mapping will be fed into a patient stratification strategy coupling unsupervised clustering with a machine-learning construction of a classifier. The final objective is to identify genetic subtypes of psychosis, provide a classifier for these subtypes and build subtype-specific genotype \u2013 endophenotype association maps. This potentially high-impact result-generating research program, along with a five-course training program, Dr. Bramon\u2019s supervision and the excellent research environment provided by UCL, will allow me to acquire the scientific and transferable skills and build the collaboration network necessary to launch my career as an independent researcher.", "To": ["2019-07-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-15"], "Project_ID": ["747429"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU"], "EU_Contribution": ["EUR 208 400,40"], "Project_Title": ["High-Performance Indexing for Emerging GPU-Coupled Databases"], "Total_Cost": ["EUR 208 400,40"], "Country": ["Norway"], "Project_ACR": ["CoupledDB"], "Technology_Description": "\"Index structures are foundational to the performance of database systems and large-scale simulations. Even small advances in indexing can therefore have widespread, sweeping impact on both industry competitiveness and scientific productivity. The confluence of several hardware trends is setting the stage for disruptive innovation in database indexing: deescalating costs of memory make it feasible to organise most of the \"hot\", frequently accessed data in memory rather than on disk; and increasingly commonplace accelerators such as graphics processing units (GPUs) offer large-scale parallelism with a lower energy footprint. Thus, in-memory indexing that exploits GPUs could be much cheaper, faster, and greener.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["753810"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["OSPEDALE SAN RAFFAELE SRL"], "EU_Contribution": ["EUR 168 277,20"], "Project_Title": ["Spatiotemporal dynamics of CD8+ T cell responses to hepatocellular carcinoma"], "Total_Cost": ["EUR 168 277,20"], "Country": ["Italy"], "Project_ACR": ["Hepatocarcinoma IVM"], "Technology_Description": "CD8+ T cells have a key role in eliminating tumors that affect the liver. The protective capacity of these cells relies on their ability to migrate to the liver, recognize antigens and deploy effector functions. While some of the rules that characterize CD8+ T cell behavior in the cancerous liver have been characterized at the population level, we have only limited knowledge of the precise dynamics of intrahepatic CD8+ T cell conduct at the single-cell level. In preliminary data for this project we have developed advanced imaging techniques that allow us to dissect the interactive behavior of CD8+ T cells within the mouse liver at an unprecedented level of spatial and temporal resolution. We predict that this approach, combined with a new model of hepatocellular carcinoma created ad hoc, will generate novel mechanistic insights into the spatiotemporal determinants that govern the capacity of CD8+ T cells to home and function in the tumor-bearing liver.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-SE - Society and Enterprise panel"], "Coordinated_in": ["Italy"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-07-01"], "Project_ID": ["753534"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["EIDGENOESSISCHE ANSTALT FUER WASSERVERSORGUNG ABWASSERREINIGUNG UND GEWAESSERSCHUTZ"], "EU_Contribution": ["EUR 175 419,60"], "Project_Title": ["Exposure of aquatic ecosystems to antifungal azoles : assessment of occurence and fate in sediment, water and aquatic organisms"], "Total_Cost": ["EUR 175 419,60"], "Country": ["Switzerland"], "Project_ACR": ["EXPOZOL"], "Technology_Description": "This project aims to provide a comprehensive characterization of the exposure of aquatic organisms to antifungal azoles (AFAs), an emerging pollutant family of particular concern as regard to their endocrine disrupting effects, in the frame of their environmental risk. To this end, this project will address different scientific and technical challenges as regards distribution, bioavailability, toxicokinetic, and (bio)transformation products ((bio)TPs) of AFAs. For this purpose , a multi-disciplinary approach, based on bio-monitoring, passive sampling, effect-driven approach, cutting-edge high resolution mass spectrometry-analyses and laboratory experiments will be implemented. This comprehensive approach will allow (1) to characterize the distribution of AFAs in aquatic systems between sediment, surface water and biota; (2) to identify bioTPs (and biotransformation pathways) of AFAs at different trophic levels but also TPs from other relevant processes (e.g. hydrolysis). This project is original and innovative since it aims to gain knowledge on exposure and identity of (bio)TPs and thus addresses a crucial issue in the assessment of environmental contamination by emerging pollutants and their associated risk. In addition, it proposes to better link exposure and hazard by studying the bioavailability of potentially hazardous chemicals directly in the organisms. It also compare passive sampling vs biomonitoring at different trophic level for a more relevant exposure monitoring of emerging pollutants such as AFAs. This might also enhance human health risk assessment by providing tools for better evaluate exposure, and so risk, associated to consumption of contaminated food (i.e. fish). Finally, if we focus in the present project on AFAs and their (bio)TPs, the approach proposed here could provide a conceptual framework for exposure assessment of other classes of emerging contaminants that would help to enhance actual environmental risk assessment for aquatic organisms.", "To": ["2019-09-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Research Organisations"], "From": ["2017-09-15"], "Project_ID": ["744052"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["OSPEDALE SAN RAFFAELE SRL"], "EU_Contribution": ["EUR 168 277,20"], "Project_Title": ["Epigenetic approach for the treatment of obesity"], "Total_Cost": ["EUR 168 277,20"], "Country": ["Italy"], "Project_ACR": ["EASY"], "Technology_Description": "It has been estimated a threefold increase in the number of obese people in Europe since the 1980\u2019s. Currently, EU countries spend an average of 7% of their public health budgets on diseases linked to obesity. The socio-economic impact of obesity epidemic cannot be overrated. European societal needs require desperately a shift forward in the field of obesity research to be able to build new therapeutics strategies. Recent scientific evidences point toward a role of epigenetic changes as major contributor in the obesity etiology. In the last decades, a huge amount of data clearly link epigenetic dysregulation to obesity onset. Yet, it remains unclear whether epigenetic dysregulation contributes meaningfully to obesity epidemic. Because weight gain only occurs when energy intake exceed energy expenditure, burning off excess fuel represent an attractive path to reduce obesity when diet and exercise are not enough. My preliminary data indicate the histone methyltransferases Suv420h1 and Suv420h2 as pivotal players in metabolism regulation. By using knockout mice specifically in brown adipose tissue, this project aims at dissecting the role of Suv420h proteins in the etiology of obesity. I will combine in vivo and in vitro analyses and genome wide studies to: 1) dissect the role of Suv420h proteins in the epigenetic regulation of the pathways controlling weight balance in response to nutritional or environmental stimuli; 2) identify genes involved in the generation, maintenance or transmission of the epigenetic memory of exposure; 3) provide useful markers or therapeutic targets to treat obesity and metabolic diseases. My results have the potential to translate into therapeutics. This research will contribute to provide new clinical targets against obesity. The Experienced Researcher will emerge from the project with new skills, and the capability to lead her own research group.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-SE - Society and Enterprise panel"], "Coordinated_in": ["Italy"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-07-01"], "Project_ID": ["746974"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITEIT MAASTRICHT"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["Behavioural Economics in Network Games"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["BEING"], "Technology_Description": "Three aspects of social interaction shall be combined, namely the diffusion of information in a social network, the formation of social networks, and behavioural (i.e. irrational) aspects in decision making. These three areas are crucially interdependent: ", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["747614"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["AARHUS UNIVERSITET"], "EU_Contribution": ["EUR 200 194,80"], "Project_Title": ["Quantification of oxidative sulphur cycling in marine sediments"], "Total_Cost": ["EUR 200 194,80"], "Country": ["Denmark"], "Project_ACR": ["SedSulphOx"], "Technology_Description": "The goal of this proposal is to quantify the rates and processes of sulphide oxidation in coastal sediments. The marine sulphur cycle is driven by the reduction of sulphate to sulphide coupled to microbial decomposition of organic matter, a process which is responsible for up to 50 % of carbon mineralisation in coastal sediment and is intimately connected to earth\u2019s biogeochemical evolution. The sulphide produced by sulphate reduction may either react with Fe to be buried as pyrite or may be oxidised through different pathways and intermediates. The amount of sulphide that is oxidised in marine sediments is not known, yet oxidative sulphur cycling has critical implications for estimates of sulphate reduction, sub-seafloor carbon mineralisation, methane oxidation, microbial metabolism and the interpretation of ancient and modern stable isotope signatures. Quantification of oxidative sulphur cycling, including sulphide oxidation rates, the formation of key intermediate species and associated stable isotope effects is therefore fundamental to our understanding of sub-seafloor biogeochemistry. ", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["746872"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Modulating and Profiling Receptor Tyrosine Kinase S-palmitoylation in Breast Cancer"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["RTKPalm"], "Technology_Description": "Breast cancer is one of the most diagnosed cancers and the leading cause of cancer death in women worldwide. Breast cancer cells need activated receptor tyrosine kinases (RTKs) to invade, proliferate, and metastasize. Increased activity and overexpression of RTKs is associated with poor prognosis for breast cancer patients. Therefore, multiple RTKs have emerged as attractive therapeutic targets. However, resistance to therapies is a persistent problem for the development of therapeutics targeting RTKs. New and innovative approaches to effectively target these receptors are required. Recently S-palmitoylation has been identified as an important post-translational modification that regulates signal transduction, protein trafficking and degradation of specific RTKs in breast cancer. The substrate scope, role, extent of dysregulation and the enzymes responsible for the S-palmitoylation of specific substrates in breast cancer is largely unknown. In this context, the aim of the proposed project is to implement novel chemical biological tools and methods, to gain insight in the extent, regulation and role of S-palmitoylation of RTKs in breast cancer. This insight will facilitate the identification of new approaches to therapeutically target RTKs in breast cancer.", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["750409"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["VYSOKA SKOLA CHEMICKO-TECHNOLOGICKA V PRAZE"], "EU_Contribution": ["EUR 142 720,80"], "Project_Title": ["Novel MAterial and Process Design for ReVerse Electrodialysis-Water ELectrolysisEnergy System"], "Total_Cost": ["EUR 142 720,80"], "Country": ["Czech Republic"], "Project_ACR": ["MARVEL"], "Technology_Description": "Development of renewable energy resources that can address energy and environmental issues is currently the top global challenge. Reverse Electrodialysis (RED) is a highly innovative technology for conversion of salinity gradient energy into electricity. Water electrolysis is a promising option for hydrogen production from renewable energy resources. Recently, a novel approach combining RED and Alkaline Polymer Electrolyte Water Electrolysis (APEWE) was reported for sustainable hydrogen production. However, this process achieved low efficiency: RED suffers from the negative impact of multivalent ions on power generation, whereas APEWE lacks highly conducive and stable membrane separators and polymer binders. The MARVEL project aims to i) endow monovalent ion selectivity for RED membranes to reduce the influence of multivalent ions ii) develop novel, fully characterized membrane separators and polymer binders for APEWE iii) test RED-APEWE process with these new materials iv) perform a techno-economic assessment for commercial feasibility. The ultimate goal of MARVEL is to broaden the knowledge and expertise of the researcher, Dr. Ramato Ashu Tufa, through high-quality research training in the emergig area of renewable energy involving multidisciplinary investigation approaches and intersectoral secondments. This allows him to establish a long-standing relationship with his institute and increase his professional network across Europe. An effective dissemination of project results and knowledge will be implemented through presentations of results in major conference, seminars, publications in high-impact peer reviewed journals, project web page, open days etc. Profound outputs from MARVEL will significantly contrubte towards establishment of a strong scientific and technical base for European science and technology, foster the competitiveness and growth of EU economy with a positive impact on the major objectives of energy policy for sustainability and security.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Czech Republic"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["748683"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITEIT MAASTRICHT"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["Wage transparency in companies"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["WAGETRANS"], "Technology_Description": "How much information about the wage structure should a company provide to its employees? Existing research in economics does not provide clear recommendations in this respect. Transparent information about the wages within a company may have a positive impact on employee satisfaction and motivation, because wage secrecy creates distrust and favours discriminatory practices. Yet, it is unclear whether the benefits of wage transparency are larger than the potential harm: Unequal wage profiles, if made transparent, trigger social comparisons among employees that may destroy work motivation and increase the likelihood of leaving the firm.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["745894"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Land Use and Resource Management at the Agricultural - Forest Frontier"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["LARMAR"], "Technology_Description": "In this fellowship, I aim to explore the trade-off and synergies between conservation and commodity production through an Ecosystem Services (ES) lens in order to determine how sustainable land use practices can be created and strengthened over time, and to extend knowledge on ES within broader land use, and natural capital research. I will carry out targeted fieldwork to investigate the following research lines: 1) how ES are defined and conceptualised as commodities and how these relate to more established \u2018land\u2019 commodities. This research line will include ES to humans, but also factors causing ecosystem change that can affect the long-term resilience of such ecosystems, by examining selected drivers of land use change. Research line 2) relates to the impact of appropriation of land for commodities (e.g., the demand for cash crops such as soy, biofuels and land used for livestock production or conservation) on local communities, and the global economy and policies that may drive (the current or any) 'land grabs'. I will take into account the discourse, practices and social relationships around land use that are currently unfolding within the 'realpolitik' of a studied region. These phenomena are highly debated yet remain poorly understood and should become key analytical domains for academics insofar that they are related to broader processes of economic globalization, biodiversity loss and climate change. The findings will be complementary to climate change mitigation efforts and feed into policy processes around securing food security, with an objective to not only contribute to sustainable land use practices but to promote the livelihood opportunities and environmental quality of (often) marginalized communities living in and around contested land.", "To": ["2019-05-01, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-02"], "Project_ID": ["745744"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["The influence of Environmental Variability On Mussel Aquaculture and adaptation in the context of global ocean change"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["EVOMA"], "Technology_Description": "Global ocean change (GOC, including warming and acidification) poses one of the largest threats to marine fisheries and aquaculture. Yet, there are still few predictive consequences, due to the limited understanding of species\u2019 in situ responses. Recent studies suggest that spatial differences in environmental conditions influence physiological tolerances of marine populations. This project tests the hypothesis that environmental variability of multiple stressors (temperature, pH, salinity) enhances physiological hardiness of sensitive early life-stages of an economically valuable mollusk, the mussel Mytilus galloprovincialis. The project implements a novel, three-pronged, multidisciplinary approach using (1) population comparisons to assess performance of mussels from sites of low and high environmental variability, (2) mild stress exposures to test for enhanced physiological performance in the field, and (3) larval cultures to assess proteomic responses to temporal variability of multiple stressors and carryover effects to juveniles. This project includes collection of oceanographic time-series data at field sites (including at an aquaculture farm), with state-of-the-art pH sensors, to identify frequency of stress events and inform experimental design. This still rare approach, using in situ data with laboratory studies, improves environmental realism in GOC studies. The project addresses a crucial gap in the current understanding of coastal environmental variability and multiple stressors and has direct application to aquaculture practices. By combining the researcher\u2019s and host\u2019s expertise on marine physiology related to GOC pressures, this project will advance innovations in the field of GOC biology, state-of-the-art pH sensor technology transfer, and applied proteomics, and will thus become an important step forward in the career of a Researcher dedicated to GOC biology, and strengthen European expertise in these fields.", "To": ["2019-11-15, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-11-16"], "Project_ID": ["747637"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITEIT MAASTRICHT"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["Learning to bracket broadly"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["BROAD"], "Technology_Description": "As a consequence of reforms of the social security systems in the EU, consumers increasingly face numerous investment decisions that involve risk, such as how to allocate their retirement savings between risky and safe assets. However, consumers often fail to make optimal choices. A key aspect in this context is whether and how people integrate (or \u201cbracket\u201d) the many different choices under risk they face. Evidence suggests that people often bracket narrowly, i.e., they view each choice in isolation and not in the context of the other choices they face, thereby often making choices that are not in their best interest. ", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["749741"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITEIT UTRECHT"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["New non perturbative methods for out-of-equilibrium quantum field theory"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["NpQFT-NEq"], "Technology_Description": "A full understanding of the out-of-equilibrium dynamics of many-body quantum systems is one of the ultimate goals of statistical physics. It is often extremely difficult to compute how physical quantities evolve with time in these settings, and to know when and how these systems eventually can reach some form of equilibrium. This difficulty is specially marked in systems described by quantum field theory, where non equilibrium dynamics are still less well understood than in discrete lattice models and quantum spin chains. ", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["750092"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["RUHR-UNIVERSITAET BOCHUM"], "EU_Contribution": ["EUR 119 595,60"], "Project_Title": ["The Continuation of Politics with Other Means: War and Protest, 1914-2011"], "Total_Cost": ["EUR 119 595,60"], "Country": ["Germany"], "Project_ACR": ["COPWOM"], "Technology_Description": "\"This project looks at the political means employed by those who, for various reasons, resorted to protest during times of war in the period from the First World War to the Iraq War. In most cases, the challengers embraced alternative means of political articulation due to the established channels of political decision making being controlled by the supporters of the war in question. Case studies illuminate the manifestations of war-time protest in different wars including both the well-known and some of the \"forgotten wars\": First World War, Spanish Civil War, Second World War, Korean War, Vietnam War, Soviet War in Afghanistan, Falklands War, Kosovo War and Iraq War. The project pursues the objective to articulate the relationship between war and protest and to develop further the debate surrounding war as a channel of cultural, social and political change. It will advance research into the comparative dimension of war-time protest by embedding this investigation in an analytical framework focused on the methods and questions of historical enquiry into social movements, and to give further specificity to the debate on processes of politicisation and depoliticisation with particular focus on the variety of motivations that drove war-time protest beyond just pacifism. This analysis combines methods from the history of protest and social movements, the history of war, the history of political thought as well as film and visual studies. The project provides conceptual tools and evidence on the pre-history of present-day protests, e.g. against U.S. unilateralism in Iraq. Via a number of publications and engagement events, especially in conjunction with public film screenings, it will create impact by intervening in current debates about the repercussions of global warfare and by furthering public awareness of the crucial historical role of war-time protest in the European political heritage.\"", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["748012"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 246 668,40"], "Project_Title": ["Redox-responsive Magnetic Materials based on Polynuclear Organometallics"], "Total_Cost": ["EUR 246 668,40"], "Country": ["France"], "Project_ACR": ["RMTBRC"], "Technology_Description": "This proposal describes the synthesis of novel functional materials by incorporating high spin octahedral metal clusters with fascinating electronic and magnetic properties into polymeric assemblies. The resulting highly redox-responsive magnetic materials will be of great interest for a variety of applications including the storage and transfer of electrical charge, gas separation via magnetic selectivity, electrocatalysis, and long range cooperative magnetic properties will also be investigated. The experienced researcher (Dr. Musgrave) wishes to spend 24 months at Harvard University to focus on synthesis and redox activity under the supervision of Prof. Theodore Betley, and 12 months at the Centre de Recherche Paul Pascal (CRPP) to carry out magnetic measurements and data modelling under the supervision of Dr. Rodolphe Cl\u00e9rac. The complementary expertise of Prof. Betley (cooperative redox chemistry and catalysis) and Dr. Cl\u00e9rac at the CRPP (electronically active and magnetic materials) are ideally suited for the completion of research objectives. Dr. Musgrave trained in the Manners group at the University of Bristol, and has extensive experience in metallopolymer synthesis and characterisation, which is of great relevance to the project. With an MSCA fellowship, Dr. Musgrave hopes to gain valuable experience in the fields of redox catalysis and magnetic materials, build a network of long-lasting collaborations with international scientists, and improve her leadership and management skills. The fellowship will have an extremely positive impact on her chances of obtaining an independent research position in the EU, and on the success of her career.", "To": ["2020-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2017-07-01"], "Project_ID": ["752684"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITEIT MAASTRICHT"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["Liver steatosis drives muscle atrophy in type 2 diabetes patients."], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["LiSDMA"], "Technology_Description": "Problem: Muscle atrophy is defined as a decrease in muscle mass, and is a major problem in many patients with type 2 diabetes (T2D). Previous studies have linked a fatty liver to the development of muscle atrophy in T2D patients, but the exact mechanisms are unknown. Background: Many T2D patients are characterised by hepatic steatosis. We have preliminary data to suggest that secretion products from the steatotic liver play an important role in the development of muscle atrophy. Aim: we will identify how hepatic steatosis affects the liver secretory profile, and we will determine the impact of these secretion products on muscle protein metabolism. We will also identify novel liver-secreted proteins that are causally related to muscle atrophy, and validate these proteins in patients with hepatic steatosis and T2D. Hypothesis: We hypothesize that hepatic steatosis changes the liver protein secretion profile which negatively impacts muscle mass. We also expect to identify proteins that are causally related to muscle atrophy, and to validate these proteins in patients with liver steatosis and T2D. Methods: We will use a translational approach in which leads from human studies will be investigated in cell- and animal experiments and subsequently tested again in human subjects. We will combine functional metabolic assays, high-throughput molecular biology approaches, cell biology and in vivo studies to investigate whether secretion products from the liver play a role in the development of muscle atrophy. Outcome: This project is the first to investigate whether secretion products from the liver directly contribute to the loss of muscle mass in T2D patients. Our research is innovative and will provide crucial proof-of-concept information to further develop therapeutic approaches to treat or prevent muscle atrophy in T2D patients.", "To": ["2020-02-20, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-02-21"], "Project_ID": ["748944"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI PARMA"], "EU_Contribution": ["EUR 244 269"], "Project_Title": ["Using consumer science to improve healthy eating habits"], "Total_Cost": ["EUR 244 269"], "Country": ["Italy"], "Project_ACR": ["CONSUMEHealth"], "Technology_Description": "Although modern consumer can make informed decisions about the types and quantity of food which are best for a healthy lifestyle, an increase in diet-related health problems -caused by unhealthy and over-eating\u2013 has been recorded in the European Union in recent years.", "To": ["2020-06-27, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-28"], "Project_ID": ["749514"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["POLITECHNIKA LUBELSKA", "TECHNICKA UNIVERZITA V KOSICIACH", "UNIVERSIDADE DO MINHO", "ZAMAK MERCATOR SPOLKA Z OGRANICZONAODPOWIEDZIALNOSCIA", "BORRA SRO", "SEZ KROMPACHY AS"], "EU_Contribution": ["EUR 1 305 000"], "Project_Title": ["Investigation and development of a new generation of machines for the processing of composite and nanocomposites materials"], "Total_Cost": ["EUR 1 305 000"], "Country": ["Poland", "Slovakia", "Portugal", "Poland", "Czech Republic", "Slovakia"], "Project_ACR": ["NEWEX"], "Technology_Description": "The main research goal of the NEWEX Project is the construction and testing of the new innovative extruder. By the application of a new, patented concept of vital parts: innovative active grooved feed section (IAGFS), original rotational barrel segment (ORBS) and special screw (SS) a completely new breakthrough technology of extrusion and plasticizing systems will be achieved. It will ensure manufacturing the products of improved properties and will enable processing materials that couldn\u2019t be processed so far, as well as food materials, cosmetic and pharmaceutical. In parallel to the main RTD activities the NEWEX project is aiming at industry-academia cooperation and transfer of knowledge between organizations from central-eastern and Western Europe. All the project\u2019s activities will be performed by thoroughly planned secondments and appropriate hosting institutions between industrial and academic partners. The workplan consists of 7 Workpackages, out of which: WP1-4 focus on the investigation of extruder, extrusion process and extrudate properties and tasks aiming at the selection of the best solution of new extruder vital parts, than construction and testing of new generation extruder. WP5 concentrates on networking activities (workshops, training, knowledge exchange, etc.). WP6 aims at knowledge dissemination (participation in conferences, fairs, publications, etc.), WP7 is dedicated to management and administration of the whole project. The consortium consists of 6 organizations: 3 representing academic partners and 3 representing industry partners. Project is coordinated by Lublin University of Technology (Poland). Partners are: Technical University of Kosice (Slovakia), University of Minho (Portugal), Zamak-Mercator LLC (Poland), SEZ-Krompachy a.s. (Slovakia) and Borra s.r.o. (Czech Republic). Realization of NEWEX project will foster the real industry-academia cooperation which is of the key importance in terms of European Research Area development strategy.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Poland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["734205"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["KING'S COLLEGE LONDON"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Differentiated health impacts of primary and secondary ultrafine particles"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["Health1UP2"], "Technology_Description": "Exposure to particulate matter (PM) has been linked to negative health effects. Traditionally attributed to PM<10\u00b5m and<2.5\u00b5m, negative health effects may be enhanced with decreasing particle size, suggesting that ultrafine particles (UFP, PM<0.1\u00b5m) might be responsible for what has previously been attributed to larger size fractions of PM.", "To": ["2019-09-06, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-07"], "Project_ID": ["747882"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITEIT MAASTRICHT", "UNIVERSITAETSKLINIKUM AACHEN", "KAROLINSKA INSTITUTET"], "EU_Contribution": ["EUR 3 832 965,36"], "Project_Title": ["International Network for Training on Risks of vascular Intimal Calcification And roads to Regression of cardiovascular diseasE"], "Total_Cost": ["EUR 3 832 965,36"], "Country": ["Netherlands", "Germany", "Sweden"], "Project_ACR": ["INTRICARE"], "Technology_Description": "Cardiovascular disease remains one of the major challenges of contemporary society, being responsible for a staggering 47% of deaths in Europe. Vascular calcification in particular requires immediate attention as it is strongly associated with increased cardiovascular mortality and morbidity, and is recognised as an important independent risk factor for cardiovascular death. Recent reports demonstrate that especially punctuated and spotty calcifications (microcalcifications) in the plaque are life-threatening. Microcalcifications are particularly prominent in the vulnerable atherosclerotic plaque that is at high risk of rupture, a cardinal event that can cause thrombosis, infarct, cardiac arrest, stroke and death. In fact, 20% of European deaths are directly attributable to thrombotic rupture of a vulnerable plaque; a clear indication that current treatments and preventive measures are insufficient. Recent findings suggest a link between vascular smooth muscle cell phenotype mediated calcification and inflammation, which could underlie the plaque destabilising effects of microcalcification. However, a comprehensive view on what causes microcalcification and its impact on plaque stability remains elusive and there is an urgent need to translate experimental findings into adequate diagnostic, preventive and therapeutic solutions. INTRICARE is shaped to address the urgent unmet medical needs concerning calcification-induced vulnerable plaques and is guided by the academic and industrial demand for a new generation of entrepreneurial scientists that have the skills, expertise and knowhow to expedite our understanding of vascular calcification and translation thereof into concrete, effective clinical solutions. The INTRICARE ESRs harbour ongoing vitamin K-supplementation trials that will be pivotal in the identification of selective biomarkers for microcalcification and subsequent development of strategies for prevention or amelioration of vulnerable plaque formation.", "To": ["2021-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EJD - European Joint Doctorates"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-03-01"], "Project_ID": ["722609"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Multi-well High-resolution Electrophysiology Platform"], "Total_Cost": ["EUR 150 000"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["MwHresEP"], "Technology_Description": "MwHresEP: Multi-well High-resolution Electrophysiology Platform", "To": ["2018-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["755383"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Innovative fungal strains for producing blue cheeses"], "Total_Cost": ["EUR 150 000"], "Country": ["France", "France"], "Project_ACR": ["BLUE"], "Technology_Description": "The ERC project GenomeFun has revealed a substantial genetic and phenotypic variability within Penicillium roqueforti, which is the fungus used for the maturation of blue cheeses. The ERC project GenomeFun has also shown the existence of different genetic clusters harboring specific traits and has allowed the development of a protocol for inducing in the laboratory the natural process of sexual reproduction in this fungus. The present PoC BLUE project aims at proving the possibility to obtain and identify, in sexual progeny, strains of P. roqueforti with novel combinations of traits of industrial interest. This would enable strain improvement, and would allow the production of blue cheeses with innovative characteristics, as desired by producers and consumers. Thus the objective of the present PoC project is to identify progeny with interesting combinations of traits. These strains will then be protected and commercialized. The project therefore also aims at identifying the market and the best strategy for exploitation, firstly by defining the most suited approach for the protection and exploitation of intellectual property, taking into account the market practices and conditions, and secondly, by verifying the legal dispositions applicable to sexual progeny of micro-organisms in the field of \u201cnovel food\u201d, biodiversity and genetic resources protection. The legislative framework raises interesting questions in the context of recent treaties on biodiversity. The consequences of the recent laws on biodiversity on the use and protection of micro-organisms as intellectual property in the fields of food are still unclear. The results of these investigations could thus serve as a model case.", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["754761"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["THE UNIVERSITY OF SHEFFIELD", "THE UNIVERSITY OF SHEFFIELD"], "EU_Contribution": ["EUR 149 995"], "Project_Title": ["Gene Editing as Therapeutic Strategy for C9ORF72 Linked ALS/FTD"], "Total_Cost": ["EUR 149 995"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["CORFEDITING"], "Technology_Description": "Expansion of a hexanucleotide repeat G4C2 in the non-coding region of chromosome 9 open reading frame 72 (C9orf72) is the most common genetic cause for amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). ALS is a fatal condition characterized by progressive motor deficits, degeneration of upper and lower motor neurons (MNs) and death from neuromuscular respiratory failure in the majority of afflicted individuals within 3-5 years. Currently, the economic burden of care and treatment for patients with ALS/FTD is expensive and continues to significantly rise in Europe and worldwide. While significant genetic discoveries have been made in the field, they have not yet translated to treatment options for patients with ALS and FTD. Thus, research efforts aimed at identifying therapeutic targets are of the utmost importance to enable therapeutic development for these devastating disorders. In this ERC Proof of Concept project, we will design, optimise and test gene therapy vectors containing CRISPR/Cas9 system to selectively remove the pathogenic ALS/FTD-related C9orf72 hexanucleotide repeat expansion in mouse models of C9orf72-related ALS, with the ultimate aim of designing a therapy for patients with C9orf72-related ALS/FTD. The ultimate benefit of this approach goes far beyond just ALS/FTD however. A successful CNS gene therapy for C9orf72 related disease potentiates the prospect of developing similar approaches to treat multiple disease scenarios amenable to gene modification. Indeed, growing evidence suggests that C9orf72 repeat expansions also contribute to a wide spectrum of neurodegenerative diseases such as Alzheimer\u2019s, Huntington\u2019s, multiple sclerosis, Parkinson\u2019s disease and cerebellar ataxias. We therefore anticipate that our strategy could be beneficial for other neurological conditions.", "To": ["2018-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["754994"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["UNIVERSITEIT MAASTRICHT", "UNIVERSITE DE STRASBOURG", "UNIVERSIDAD DE ALICANTE", "UNIVERSITAET AUGSBURG", "QUEEN MARY UNIVERSITY OF LONDON"], "EU_Contribution": ["EUR 3 865 881,60"], "Project_Title": ["European Intellectual Property Institutes Network - Innovation Society"], "Total_Cost": ["EUR 3 865 881,60"], "Country": ["Netherlands", "France", "Spain", "Germany", "United Kingdom"], "Project_ACR": ["EIPIN IS"], "Technology_Description": "EIPIN IS is a comprehensive project at the forefront of multidisciplinary research, examining the role of intellectual property (IP) as a complex adaptive system in innovation. The focus will be on the European regulatory framework for fostering innovation with the aim of enhancing Europe\u2019s capacity for innovation-based sustainable economic growth. ", "To": ["2021-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EJD - European Joint Doctorates"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-03-01"], "Project_ID": ["721733"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["UNIVERSITEIT UTRECHT"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["Linking Zeolite Porosity to Molecular Diffusion at the Single Crystal Level"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["ZeoPoreDiff"], "Technology_Description": "Zeolites are the key enablers of diverse chemical reactions, fulfilling a role of utmost importance in (petro-) chemical industry. They contain a precisely defined micropore network, which exposes a 3-D distribution of Br\u00f8nsted acid sites. The performance of zeolites relies to a great extent on the accessibility of these acid sites, making the facile molecular diffusion through the zeolite pore network essential. For this reason, methods for hierarchical porosity development \u2013 such as steaming \u2013 are used to increase the molecular uptake of zeolites. These methods introduce auxiliary meso- and macroporosity, which maximize the utilization of the catalyst volume, and thereby improve the catalyst performance and lifetime. ", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["748563"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE"], "EU_Contribution": ["EUR 149 959"], "Project_Title": ["Novel water splitting catalysts for efficient alkaline electrolyzers"], "Total_Cost": ["EUR 149 959"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["ELECTROCAT"], "Technology_Description": "Renewable energies such as solar and wind are intermittent and require efficient storage methods. One of the most promising methods for renewable energy storage is water splitting, which converts these energies into hydrogen fuel. Solar or wind-driven water splitting can be done using electrolyzers, and alkaline electrolyzers are potentially scalable because they do not use precious metal catalysts. However, current alkaline electrolyzers employ catalysts that have low efficiencies and are prone to corrosion. This project aims to apply several novel classes of water splitting catalysts developed in our ERC Starting Grant project in alkaline electrolyzers. The catalysts are inexpensive and have higher energy efficiencies than those employed in commercial alkaline electrolyzers. They are potentially more stable as well. The goal of the project is to provide technology demonstrators for the use of these catalysts in alkaline electrolyzers, which is expected to result in higher efficiencies and stability at a similar cost.", "To": ["2018-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["754760"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich"], "EU_Contribution": ["EUR 2 130 088"], "Project_Title": ["Cold Ion Chemistry - Experiments within a Rydberg Orbit"], "Total_Cost": ["EUR 2 130 088"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["CICERO"], "Technology_Description": "\"To date no experiment has investigated ion-molecule reactions at temperatures significantly below about 20 K, for two reasons: (i) Cooling the translational and internal degrees of freedom of ions and molecules is extremely challenging. (ii) Even very weak stray electric fields accelerate the ions. A potential difference of only 1 mV across the reaction volume imparts a kinetic energy of 1 meV to ions, which corresponds to a temperature of about 12 K. Quantum mechanical effects arising from the translational and the frozen or hindered rotational motion of the reactants in the intermolecular potential are only expected to be significant below 20 K and have therefore not been observed yet in ion-molecule reactions, even for reactions involving the lightest ions and molecules. This proposal aims at developing a new experimental method to study ion-molecule reactions at temperatures down to 100 mK and to study ion-molecule reactions involving light species, with particular emphasis placed on the observation and quantification of quantum effects in low-temperature ion-molecule chemistry. To reach this goal, we will study the ion-molecule reactions within the orbit of a highly excited Rydberg electron, which will shield the reaction from stray fields without affecting its outcome. To reach very low collision energies, we will use a merged-beam approach relying on a surface-electrode Rydberg-Stark deflector. In the preparatory phase of this proposal, we have carried out a proof-of-principle measurement of the H2+ + H2 -> H3+ + H reaction below 1 K using a simplified version of the \"ideal\" instrument and demonstrated the feasibility of our method. We now plan to exploit the full potential of our new approach and study important ion-molecule reactions in a temperature range thought until now to be experimentally inaccessible.\"", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["743121"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["TECHNISCHE UNIVERSITEIT DELFT", "TECHNISCHE UNIVERSITEIT DELFT"], "EU_Contribution": ["EUR 2 499 474"], "Project_Title": ["Virtual Seismology: monitoring the Earth's subsurface with underground virtual earthquakes and virtual seismometers"], "Total_Cost": ["EUR 2 499 474"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["VirtualSeis"], "Technology_Description": "If it were possible to place seismometers and seismic vibrators anywhere below the ground in, for example, an induced-earthquake-sensitive area, we could measure the source mechanism of actual earthquakes, monitor the geomechanical state of the area over time, and quantify the ground motion caused by possible future earthquakes. Moreover, we could monitor fluid flow in aquifers, geothermal reservoirs or CO2 storage reservoirs, with unprecedented resolution. Unfortunately, placing seismic instruments anywhere below the ground is not practically feasible. ", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["742703"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITY OF DUNDEE", "UNIVERSITY OF DUNDEE"], "EU_Contribution": ["EUR 2 128 602"], "Project_Title": ["Evolution of multicellularity and somatic cell specialization"], "Total_Cost": ["EUR 2 128 602"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["EVOSOM"], "Technology_Description": "The evolution of multicellularity allowed specialization of cells into functions that support rather than cause propagation. While yielding immense gain of function, the organisation of these somatic cells into tissues and organs required novel cell-cell signalling systems. We seek to identify the genetic changes that caused transitions to multicellularity and enabled cell specialization. We use genetically tractable Dictyostelia with multicellular structures that contain from 1 to 5 cell-types to address these fundamental questions. Dictyostelia evolved from unicellular Amoebozoa and are subdivided into 4 major groups, with most novel cell-types appearing in group 4. We found that gene expression patterns changed most frequently at the transition between groups 3 and 4, and that across groups ~10% of genes were alternatively spliced in the 5\u2019UTR, indicative of promoter elaboration. Among known genes essential for multicellular development, those involved in intracellular signal processing were mostly conserved between Dictyostelia and unicellular Amoebozoa, while those encoding exposed and secreted proteins (ESPs) were unique to Dictyostelia or groups within Dictyostelia. Starting from a hypothesis that diversification of ESPs and gene regulatory mechanisms are major drivers of multicellular evolution, we will place unicellular relatives of Dictyostelia under selection to induce multicellularity, establish which genes are most changed in evolved populations and whether this involves ESP families that are also most changed in Dictyostelia. We will overexpress altered genes in unicellular forms to assess whether this induces multicellularity. We will retrace evolution of cell specialization by lineage analysis and phenotyping and seek correlations between cell-type innovation and alternative splice events and with emergence of novel signalling genes. Causality will be assessed by replacement of genes or promoters with ancestral forms in evolved species and vice versa.", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["742288"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["HELSINGIN YLIOPISTO", "HELSINGIN YLIOPISTO"], "EU_Contribution": ["EUR 2 500 000"], "Project_Title": ["Atmospheric Gas-to-Particle conversion"], "Total_Cost": ["EUR 2 500 000"], "Country": ["Finland", "Finland"], "Project_ACR": ["ATM-GTP"], "Technology_Description": "Atmospheric Gas-to-Particle conversion (ATM-GTP) is a 5-year project focusing on one of the most critical atmospheric processes relevant to global climate and air quality: the first steps of atmospheric aerosol particle formation and growth. The project will concentrate on the currently lacking environmentally-specific knowledge about the interacting, non-linear, physical and chemical atmospheric processes associated with nano-scale gas-to-particle conversion (GTP). The main scientific objective of ATM-GTP is to create a deep understanding on atmospheric GTP taking place at the sub-5 nm size range, particularly in heavily-polluted Chinese mega cities like Beijing and in pristine environments like Siberia and Nordic high-latitude regions. We also aim to find out how nano-GTM is associated with air quality-climate interactions and feedbacks. We are interested in quantifying the effect of nano-GTP on the COBACC (Continental Biosphere-Aerosol-Cloud-Climate) feedback loop that is important in Arctic and boreal regions. Our approach enables to point out the effective reduction mechanisms of the secondary air pollution by a factor of 5-10 and to make reliable estimates of the global and regional aerosol loads, including anthropogenic and biogenic contributions to these loads. We can estimate the future role of Northern Hemispheric biosphere in reducing the global radiative forcing via the quantified feedbacks. The project is carried out by the world-leading scientist in atmospheric aerosol science, being also one of the founders of terrestrial ecosystem meteorology, together with his research team. The project uses novel infrastructures including SMEAR (Stations Measuring Ecosystem Atmospheric Relations) stations, related modelling platforms and regional data from Russia and China. The work will be carried out in synergy with several national, Nordic and EU research-innovation projects: Finnish Center of Excellence-ATM, Nordic CoE-CRAICC and EU-FP7-BACCHUS.", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["742206"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["INSTITUTO DE ASTROFISICA DE CANARIAS", "INSTITUTO DE ASTROFISICA DE CANARIAS"], "EU_Contribution": ["EUR 2 478 750"], "Project_Title": ["Polarized Radiation Diagnostics for Exploring the Magnetism of the Outer Solar Atmosphere"], "Total_Cost": ["EUR 2 478 750"], "Country": ["Spain", "Spain"], "Project_ACR": ["POLMAG"], "Technology_Description": "POLMAG aims at a true breakthrough in the development and application of polarized radiation diagnostic methods for exploring the magnetic fields of the chromosphere, transition region and corona of the Sun via the interpretation of the Stokes profiles produced by optically polarized atoms and the Hanle and Zeeman effects in ultraviolet (UV), visible and near-infrared spectral lines. To this end, POLMAG will combine and expand expertise on atomic physics, on the quantum theory of radiation, on high-precision spectropolarimetry, on advanced methods in numerical radiative transfer, and on the confrontation of spectropolarimetric observations with spectral synthesis in increasingly realistic three-dimensional (3D) numerical models of the solar atmosphere.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["742265"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich"], "EU_Contribution": ["EUR 2 173 375"], "Project_Title": ["Faster magic-angle spinning leads to a resolution revolution in biological solid-state NMR"], "Total_Cost": ["EUR 2 173 375"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["FASTER"], "Technology_Description": "Solid-state NMR has recently made a significant impact on structural biology by providing atomic-resolution structures of several, previously uncharacterized proteins. A particularly relevant example is the Amyloid-beta (A\u03b2) peptide linked to Alzheimer\u2019s disease where we determined the atomic-resolution structure of A\u03b2(1-42) and of the Osaka mutant of A\u03b2(1-40).", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["741863"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["KARLSRUHER INSTITUT FUER TECHNOLOGIE", "KARLSRUHER INSTITUT FUER TECHNOLOGIE"], "EU_Contribution": ["EUR 2 335 416,25"], "Project_Title": ["Molecular Quantum Opto-Spintronics"], "Total_Cost": ["EUR 2 335 416,25"], "Country": ["Germany", "Germany"], "Project_ACR": ["MoQuOS"], "Technology_Description": "The field of quantum materials has developed into an active playground for testing novel ideas and protocols for future devices governed by the principles of quantum mechanics. Quantum technologies might result in revolutionary improvements in terms of capacity, sensitivity, and speed, and will be the decisive factor for success in many industries and markets (http://qurope.eu/manifesto). ", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["741276"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITAET REGENSBURG", "UNIVERSITAET REGENSBURG"], "EU_Contribution": ["EUR 2 458 200"], "Project_Title": ["Photocatalytic Generation of CarbAnions for Organic Synthesis"], "Total_Cost": ["EUR 2 458 200"], "Country": ["Germany", "Germany"], "Project_ACR": ["PHAROS"], "Technology_Description": "Light is a fascinating reagent for chemistry as it provides energy to drive reactions, but leaves no trace. In visible light photoredox catalysis the initial electron transfer from the excited dye to a substrate yields radical anion or radical intermediates, which dominate the subsequent chemistry. Carbanions, which are the most important nucleophiles in organic chemistry, are typically not available from photocatalysis. The project PHAROS aims to overcome the current limitation of visible light photocatalysis to radical chemistry and extend its use to carbon nucleophiles. To obtain carbanions for organic synthesis using visible light, we propose three specific project tasks:", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["741623"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["INSTITUT POLYTECHNIQUE DE BORDEAUX", "INSTITUT POLYTECHNIQUE DE BORDEAUX"], "EU_Contribution": ["EUR 2 415 848,75"], "Project_Title": ["Electrochemically induced Asymmetry: from materials to molecules and back"], "Total_Cost": ["EUR 2 415 848,75"], "Country": ["France", "France"], "Project_ACR": ["ELECTRA"], "Technology_Description": "Asymmetry is a very common feature of many systems, objects and molecules, that we use in our daily life. Actually, it is in a majority of cases the absolutely crucial ingredient for conferring a useful property to a system, a prominent example being the chiral nature of pharmaceutically active compounds. Chemists have developed various approaches to generate asymmetry, from the molecular to the macroscopic scale, but are still facing major challenges when exploring efficient alternative physico-chemical concepts for symmetry breaking. The global aim of ELECTRA is to propose so far unexplored and versatile strategies, based on the unconventional use of electrochemical phenomena, to generate asymmetry in chemical systems at different length scales.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["741251"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["THE HEBREW UNIVERSITY OF JERUSALEM", "THE HEBREW UNIVERSITY OF JERUSALEM"], "EU_Contribution": ["EUR 2 026 706"], "Project_Title": ["Complexity and Simplicity in Economic Mechanisms"], "Total_Cost": ["EUR 2 026 706"], "Country": ["Israel", "Israel"], "Project_ACR": ["COMPECON"], "Technology_Description": "As more and more economic activity is moving to the Internet, familiar economic mechanisms are being deployed at unprecedented scales of size, speed, and complexity. In many cases this new complexity becomes the defining feature of the deployed economic mechanism and the quantitative difference becomes a key qualitative one. A well-studied example of such situations is how the humble single-item auction suddenly becomes a billion-times repeated online ad auction, or even becomes a combinatorial auction with exponentially many possible outcomes. Similar complexity explosions occur with various markets, with information dissemination, with pricing structures, and with many other economic mechanisms. ", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["740282"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 2 494 117"], "Project_Title": ["An Information Theoretic Approach to Improving the Reliability of Weather and Climate Simulations"], "Total_Cost": ["EUR 2 494 117"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["ITHACA"], "Technology_Description": "The aim of this project is to develop a new synergy between climate and computer science to increase the accuracy and hence reliability of comprehensive weather and climate models. The scientific basis for this project lies in the PI\u2019s pioneering research on stochastic sub-grid parametrisations for climate models. These parametrisations provide estimates of irreducible uncertainty in weather and climate models, and will be used to determine where numerical precision for model variables can be reduced without degradation. By identifying those bits that carry negligible information \u2013 typically in high-wavenumber components of the dynamical core and within parametrisation and Earth-System modules \u2013 computational resources can be reinvested into areas (resolution, process representation, ensemble size) where they are sorely needed. This project will determine scale-dependent estimates of information content as rigorously as possible based on a variety of new tools, which include information-theoretic diagnostics and emulators of imprecision, and in a variety of models, from idealised to comprehensive. The project will contribute significantly to the development of next-generation weather and climate models and is well timed for the advent of exascale supercomputing where energy efficiency is paramount and where movement of bits, being the single biggest determinant of power consumption, must be minimised. The ideas will be tested on emerging hardware capable of exploiting the benefits of mixed-precision arithmetic. A testable scientific hypothesis is presented: a proposed increase in forecast reliability arising from an increase in the forecast model\u2019s vertical resolution, the cost being paid for by a reduction in precision of small-scale variables. This project can be expected to provide new scientific understanding of how different scales interact in the nonlinear climate system, for example in maintaining persistent atmospheric flow regimes.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["741112"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["SCUOLA NORMALE SUPERIORE", "SCUOLA NORMALE SUPERIORE"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Open Correspondence Publishing and Visualization Platform."], "Total_Cost": ["EUR 150 000"], "Country": ["Italy", "Italy"], "Project_ACR": ["OPenPal"], "Technology_Description": "In Humanities, written correspondence is a fundamental object of study. The current IT revolution provides means for reassembling and disseminating this precious literary heritage for the first time, while at the same time fostering new forms of scholarly cooperation. As letters create links between people, the value of documents and data increases when different corpora of written correspondences are interconnected and linked. Despite the strong need for common standards and common tools to exploit these connections and to reconstruct the discourse of the Republic of Letters, there is still no simple framework in the current panorama for publishing digitized correspondence corpora.", "To": ["2018-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["727832"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE", "INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Epigenomic Reprogramming of Adipose Tissue Function and Energy Metabolism in Type 2 Diabetes"], "Total_Cost": ["EUR 2 000 000"], "Country": ["France", "France"], "Project_ACR": ["EpiFAT"], "Technology_Description": "Obesity is associated with adipose tissue dysfunction leading to the onset of several pathologies including type 2 diabetes (T2D). The mechanisms underlying the development of obesity and T2D include the hypertrophy and/or hyperplasia of adipocytes and adipose tissue inflammation together with an altered secretion of adipokines. However, the explanation of why individual obese (and some non-obese) humans differ in their susceptibility to develop T2D is still an issue that is currently not sufficiently addressed. This susceptibility to T2D is mainly associated with environmental factors. One link between environment and disease is epigenetics influencing gene expression and subsequently organ dysfunction. Epigenetic modifications in adipose tissue have been proposed to influence the susceptibility to T2D. However, the epigenomic mechanisms underpinning adipose tissue dysfunction are poorly known. In search for epigenomic modifiers that control adipose tissue function and also impact on T2D pathogenesis, we have recently identified the transcriptional coregulators GPS2 (G-Protein Pathway Suppressor 2) and KDM6B (Histone Lysine Demethylase 6B, also called JMJD3) as strong candidates.", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-06-01"], "Project_ID": ["725790"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY", "TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Programming with Big Code"], "Total_Cost": ["EUR 150 000"], "Country": ["Israel", "Israel"], "Project_ACR": ["AutoCode"], "Technology_Description": "Software synthesis aims to automate the creation of software by generating parts of software from a higher-level description. Until recently it was believed to be impossible to practically synthesize software beyond very small fragments. However, synthesis based on learning from existing large code-bases (\u201cBig Code\u201d) is making synthesis into a practical reality . The purpose of this PoC is to develop a platform that would lead to commercialization of our technology to improve programming productivity and code quality. We target two closely related applications: (1) Providing automatic assistance in programming tasks by learning from existing code, and (2) Providing on-line assessment of code quality as it is being developed using learned models. These applications have the potential to dramatically reduce time-to-market of new software, and improve its quality and security.", "To": ["2018-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["727579"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI MILANO", "UNIVERSITA DEGLI STUDI DI MILANO"], "EU_Contribution": ["EUR 1 602 862"], "Project_Title": ["Proton strucure for discovery at the Large Hadron Collider"], "Total_Cost": ["EUR 1 602 862"], "Country": ["Italy", "Italy"], "Project_ACR": ["NNNPDF"], "Technology_Description": "The objective of this project is to revolutionize the way the structure of the proton is accessed, determined, and used in the computation of physical processes at hadron colliders such as the Large Hadron Collider (LHC) of CERN. At a hadron accelerator, predictions require a precise, detailed, and accurate description and understanding of the structure of the colliding protons, as encoded in parton distributions (PDFs) - the distributions of quarks and gluons. At the LHC, PDFs are at present the major source of uncertainty, and in the near future they will be the main hurdle for discovery. The vision of this project is to remove this hurdle by attacking the problem using recent results from artificial intelligence (AI). I will lead a research team of two staff scientists, four postdocs and three PhD students, who will apply to PDF determination the recent methods of deep reinforcement learning and Q-learning, which will be coupled with deep residual networks to achieve a fully parameter- and bias-free understanding of proton structure. I will bring into high-energy physics a methodology so far used for object recognition in self-driving cars and automatic game playing, leading both to new physics, and new computational techniques. The application of these techniques to PDFs will enable me to reach two secondary goals. The first is theoretical: the full use for PDF determination of recent high perturbative order (next-to-next-to leading order or NNLO) computations, which will be integrated by means of a new approximation method which relies on combining known exact results with all-order information in various kinematic limits to extend the scope of the former to a more detailed (\"more exclusive\") description of the final state.The second is phenomenological: the integration in PDF determination of the Monte-Carlo event generators which are used to turn field theoretical prediction into a realistic description which may be directly compared to experimental data.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["740006"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA", "FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Rescuing Cognitive Deficits in Neurodevelopmental Disorders by Gene Editing in Brain Development: the Case of Down Syndrome"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Italy", "Italy"], "Project_ACR": ["GenEdiDS"], "Technology_Description": "Neurodevelopmental disorders (ND) are chronic psychiatric conditions with different etiologies, but most share a strong genetic component, defective brain development, and cognitive impairment. Currently, treatment options are very limited, and early educational intervention is the cornerstone for the management of cognitive impairment in most ND, indicating the positive effect of early actions during brain development. Among ND, Down syndrome (DS) is caused by the presence of an extra chromosome 21, and it represents the leading cause of genetically-defined intellectual disability. Different pharmacological treatments targeting one of the many pathways downstream of the triplicated genes have been shown to rescue cognitive impairment in DS animal models. Nevertheless, most of these preclinical studies have been performed postnatally and often in adults, possibly because of concerns of unwanted drug side effects that may have long-lasting noxious sequelae on a developing brain at embryonic stages. On the other hand, viral (but also non-viral) gene therapy approaches in animal models of ND have been mostly neglected because of technical and ethical issues, when considered in the light of future translational applications. Yet, DS is mostly diagnosed prenatally, when many of its brain developmental abnormalities originate. Here, we will investigate whether in utero manipulation of specific and possibly converging gene networks in neuronal progenitors of DS mice by CRISPR-Cas9 gene-editing technology, may recover brain development and cognitive deficits later in life. Specifically targeting neuronal progenitors will allow us to act at early stages of brain development, while avoiding the involvement of genetic editing of germline cells and all related ethical issues. In parallel, we will also develop safer (viral-free) technological approaches for genetic manipulations in utero to minimize technical issues in the view of potential future translational applications.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Chiara Andreoli", "Tel.: +3901071781854", "Fax: +39 010 7170817", "Research Organisations", "Chiara Andreoli", "Tel.: +3901071781854", "Fax: +39 010 7170817"], "From": ["2017-10-01"], "Project_ID": ["725563"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITAET MANNHEIM", "UNIVERSITAET MANNHEIM"], "EU_Contribution": ["EUR 1 212 934"], "Project_Title": ["Illicit Markets, Unobserved Competitors, and Illegal Behavior"], "Total_Cost": ["EUR 1 212 934"], "Country": ["Germany", "Germany"], "Project_ACR": ["FORENSICS"], "Technology_Description": "Many markets are characterized by illicit or illegal behavior by agents. To the extent that the empirical economic framework does not incorporate these unobserved actions or control for them in estimation, the resulting models are likely to be mis-specified. Naturally, if the models do not contain all elements relevant for decision making, then predictions based on the estimates will be misleading, which could result in incorrect policy recommendations. This project directly addresses three situations in which unobserved behavior plays a crucial role. The first concerns markets where consumers engage in illicit behavior. These markets are prevalent in society as they constitute the market for illicit drugs, which is estimated at more than $300 billion per year (UN, 2012). The second concerns markets where firms make strategic decisions in the presence of an unidentified competitor - a counterfeiter, where the global value of counterfeit products rivals that of illegal drugs (OECD, 2007). The third concerns situations where firms use legal tools for illegal purposes, for which the impact is challenging to quantify and one goal of this project. In each area, the project (i) develops state-of-the-art empirical models that incorporate illicit behaviors, (ii) proposes novel estimation methods that can be used to detect illegal behavior, and (iii) provides evidence that the proposed methodology is feasible and the data are sufficient to estimate the models. Incorporating and estimating unobserved behavior in a variety of settings is an ambitious undertaking. However, it is vital as a key objective of the proposal is to provide policy makers with tangible tools that accurately reflect the unobserved nature of these markets. Given the global significance of illicit markets, the novel concepts proposed, and the focus on policy, this project has the potential to make a sizable impact, both in and beyond academia, representing an ambitious but worthwhile pursuit.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["725081"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["INSTITUT ZA FIZIKU", "INSTITUT ZA FIZIKU"], "EU_Contribution": ["EUR 1 356 000"], "Project_Title": ["A novel Quark-Gluon Plasma tomography tool: from jet quenching to exploring the extreme medium properties"], "Total_Cost": ["EUR 1 356 000"], "Country": ["Serbia", "Serbia"], "Project_ACR": ["QGP tomography"], "Technology_Description": "Quark-Gluon Plasma (QGP) is a primordial state of matter, which consists of interacting free quarks and gluons. QGP likely existed immediately after the Big-Bang, and this extreme form of matter is today created in Little Bangs, which are ultra-relativistic collisions of heavy nuclei at the LHC and RHIC experiments. Based on the deconfinement ideas, a gas-like behaviour of QGP was anticipated. Unexpectedly, predictions of relativistic hydrodynamics - applicable to low momentum hadron data - indicated that QGP behaves as nearly perfect fluid, thus bringing exciting connections between the hottest (QGP) and the coldest (perfect Fermi gas) matter on Earth. However, predictions of hydrodynamical simulations are often weakly sensitive to changes of the bulk QGP parameters. In particular, even a large increase of viscosity not far from the phase transition does not notably change the low momentum predictions; in addition, the origin of the surprisingly low viscosity remains unclear. To understand the QGP properties, and to challenge the perfect fluid paradigm, we will develop a novel precision tomographic tool based on: i) state of the art, no free parameters, energy loss model of high momentum parton interactions with evolving QGP, ii) simulations of QGP evolution, in which the medium parameters will be systematically varied, and the resulting temperature profiles used as inputs for the energy loss model. In a substantially novel approach, this will allow using the data of rare high momentum particles to constrain the properties of the bulk medium. We will use this tool to: i) test our \u201csoft-to-hard\u201d medium hypothesis, i.e. if the bulk behaves as a nearly perfect fluid near critical temperature Tc, and as a weakly coupled system at higher temperatures, ii) map \u201csoft-to-hard\u201d boundary for QGP, iii) understand the origin of the low viscosity near Tc, and iv) test if QGP is formed in small (p+p or p(d)+A) systems.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Serbia"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["725741"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITEIT UTRECHT", "UNIVERSITEIT UTRECHT"], "EU_Contribution": ["EUR 1 998 750"], "Project_Title": ["Sharing Knowledge In Learned and Literary Networks. The Republic of Letters as a Pan-European Knowledge Society"], "Total_Cost": ["EUR 1 998 750"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["SKILLNET"], "Technology_Description": "Most scholars today are in favour of sharing their knowledge freely, even if there is no guarantee that they will get something in return. Apparently they assume that there is some greater good involved in sharing knowledge. Where does this ideal of knowledge come from?", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["724972"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE", "INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE"], "EU_Contribution": ["EUR 1 999 740"], "Project_Title": ["Extra-gonadal roles of Anti-M\u00fcllerian Hormone in the aetiology of polycystic ovary syndrome: the domino effect to reproductive neuroendocrine dysfunctions"], "Total_Cost": ["EUR 1 999 740"], "Country": ["France", "France"], "Project_ACR": ["REPRODAMH"], "Technology_Description": "Reproduction in mammals is dependent on specific neurons secreting the Gonadotropin Hormone-Releasing Hormone (GnRH). Many reproductive disorders in humans are associated with abnormal or deficient GnRH secretion. Among reproductive dysfunctions, polycystic ovary syndrome (PCOS) is the most common form of female infertility with a prevalence of up to 10%, characterized by increased ovarian androgen biosynthesis, oligo-anovulation and frequent metabolic morbidities. Because women with PCOS have increased luteinizing hormone (LH) pulse frequency, it has been inferred that the pulse frequency of GnRH must be accelerated as well. However, so far PCOS has been considered mainly as a gonadal pathology and possible regulations from the central nervous system or interactions with it remain elusive. In patients with PCOS, ovarian levels of Anti-Mullerian Hormone (AMH) are also elevated, indicating the potential relevance of AMH for PCOS diagnosis and management. Recently, we showed that AMH acts directly on GnRH neurons to increase neuropeptide secretion, raising the intriguing hypothesis that AMH-dependent regulation of GnRH release could be involved in the neuroendocrine control of fertility and pathophysiology of PCOS. By providing integrative, functional and mechanistic in vivo strategies, combined with clinical human investigations, REPRODAMH will represent a major step forward into the understanding of PCOS with the final goal of developing new therapeutic strategies. To achieve these goals we will:", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-05-01"], "Project_ID": ["725149"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["HELSINGIN YLIOPISTO", "HELSINGIN YLIOPISTO"], "EU_Contribution": ["EUR 1 972 905"], "Project_Title": ["Elucidation of intratumoral heterogeneity in Kras-driven cancers"], "Total_Cost": ["EUR 1 972 905"], "Country": ["Finland", "Finland"], "Project_ACR": ["INTUMORX"], "Technology_Description": "The considerable variability within tissue microenvironments as well as the multiclonality of cancers leads to intratumoral heterogeneity. This increases the probablility of cellular states that promote resistance to therapy and eventually lead to reconstitution of the tumor by treatment-resistant cancer cells, which in some cases have properties of normal tissue stem cells. Wnt signals are important in the maintenance of stem cells in various epithelial tissues, including in lung development and regeneration. We hypothesized that Wnt signals contribute to tumor heterogeneity in genetically engineered KrasG12D; Tp53\u0394/\u0394 (\u201dKP\u201d) mouse lung adenocarcinomas (LUAD). We observed that a subpopulation of LUAD cells exhibited high Wnt reporter activity and had increased tumor forming ability, which could be suppressed by silencing of Wnt signaling pathway components or by small molecule Wnt inhibitors in vitro and in vivo. KP LUAD cells show hierarchical features with two distinct populations, one with increased Wnt reporter activity and another forming a niche that provides the Wnt signal. Lineage-tracing experiments in the autochthonous KP tumors demonstrated that Wnt responder cells have increased tumor propagation ability in vivo. Strikingly, selective ablation of the Wnt responder cells resulted in tumor stasis. CRISPR-based targeting or small molecules targeting Wnt signaling reduced tumor growth and prolonged survival in the autochthonous KP mouse lung cancer model. These results indicate that maintenance of heterogeneity within tumors may be advantageous for the tumor cell population collectively. We propose to elucidate the molecular and cellullar mechanisms that control stem-like and niche cell phenotypes using a combination of novel lentiviral vectors and genetically modified mice in the context of the KP LUAD model. These efforts may lead to novel therapeutic concepts in human lung cancer.", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["716162"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["LIBERA UNIVERSITA DI BOLZANO", "TECHNICKA UNIVERZITA V KOSICIACH", "MONTANUNIVERSITAT LEOBEN", "ELCOM, SPOLOCNOST S RUCENIM OBMEDZENYM, PRESOV", "CHIANG MAI UNIVERSITY", "MASSACHUSETTS INSTITUTE OF TECHNOLOGY", "WORCESTER POLYTECHNIC INSTITUTE", "MADURAI AYIRA VAISYAR MANJAPUTHUR MAHAJANA SABAI"], "EU_Contribution": ["EUR 783 000"], "Project_Title": ["Industry 4.0 for SMEs - Smart Manufacturing and Logistics for SMEs in an X-to-order and Mass Customization Environment"], "Total_Cost": ["EUR 954 000"], "Country": ["Italy", "Slovakia", "Austria", "Slovakia", "Thailand", "United States", "United States", "India"], "Project_ACR": ["SME 4.0"], "Technology_Description": "Industry 4.0 refers to the fourth industrial revolution and technological evolution from embedded systems to cyber-physical systems (CPS) in production. The main objectives of Industry 4.0 can be summarized as the introduction of intelligent systems in production and logistics, the development of highly adaptable and modular manufacturing and logistics systems, the integration of sustainable and advanced manufacturing technologies as well as the promotion of automation technology and human-machine interaction. In the context of Industry 4.0 new ICT and web technologies act as booster or enabler of smart, autonomous and self-learning factories facing the challenges of even more individualized and customized product portfolio.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2017-01-01"], "Project_ID": ["734713"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["RUHR-UNIVERSITAET BOCHUM", "RUHR-UNIVERSITAET BOCHUM"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["In situ and Operando Nanocatalysis: Size, Shape and Chemical State Effects"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["OPERANDOCAT"], "Technology_Description": "Tailoring the chemical reactivity of nanomaterials at the atomic level is one of the most important challenges in catalysis research. In order to achieve this elusive goal, fundamental understanding of the structural and chemical properties of these complex systems must be obtained. Numerous studies have been devoted to understanding the properties that affect the catalytic performance of metal nanoparticles (NPs) such as their size, interaction with the support, and chemical state. The role played by the NP shape on catalytic performance is, however, less understood. Complicating the analysis is the fact that the former parameters cannot be considered independently, since the NP size as well as the support will have an impact on the most stable NP shapes. In addition, the dynamic nature of the NP catalysts and their response to the environment must be taken into consideration, since the working state of a NP catalyst might not be the state in which the catalyst was prepared, but rather a structural and/or chemical isomer that adapted to the particular reaction conditions. To address the complexity of real-world catalysts, a synergistic approach taking advantage of a variety of cutting-edge experimental methods must be undertaken. ", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["725915"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["RUHR-UNIVERSITAET BOCHUM", "RUHR-UNIVERSITAET BOCHUM"], "EU_Contribution": ["EUR 1 483 092,50"], "Project_Title": ["Protection of Redox Catalysts for Cathodic Processes in Redox Matrices."], "Total_Cost": ["EUR 1 483 092,50"], "Country": ["Germany", "Germany"], "Project_ACR": ["REDOX SHIELDS"], "Technology_Description": "Biological or molecular catalysts built from Earth-abundant elements are envisioned as economically viable alternatives to the scarce noble metals that are currently used in renewable energy conversion. However, their fragility and O2 sensitivity have been obstacles to their adoption in industry. We have recently proposed O2 quenching matrices for protecting intrinsically O2-sensitive catalysts for use in anodic (oxidative) processes. We have demonstrated that even hydrogenases, the highly sensitive metalloenzymes that oxidize H2, can be used under the harsh conditions encountered in operating fuel cells. However, attempts to reverse the concept for the protection of cathodic (reductive) processes, such as H2 evolution, have been unsuccessful so far. In this case, the electrode generates the reducing agents in the form of electrons, which are needed for both H2 generation and reductive O2 quenching. The competition between the two reactions results in insufficient protection from O2 and deactivation of the catalyst.", "To": ["2022-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-03-01"], "Project_ID": ["715900"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Smart Multimodal Microscopy for High-Throughput Developmental Biology in Real-Time"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["SmartMic"], "Technology_Description": "\"Fluorescence microscopy is a key technology in our quest to understand fundamental developmental processes of life. High-resolution images recorded in intact, living organisms deliver insights into the complex interplay of molecules, cells and tissues in real time. Even though the resolution of microscopes has been pushed beyond the diffraction limit, providing important insights into the inner workings of single cells, we still lack an understanding of plasticity in development: How does one embryo differ from another and how can we describe the \"average\", stereotypic embryo?", "To": ["2020-06-30, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2015-07-01"], "Project_ID": ["647885"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 171 792,60"], "Project_Title": ["Electrophilic-induced asymmetric boronate rearrangements via CAPT catalysis. A novel approach towards the formal trifunctionalization of alkenes."], "Total_Cost": ["EUR 171 792,60"], "Country": ["United Kingdom"], "Project_ACR": ["HALOBORYLATION"], "Technology_Description": "This proposal describes an unprecedented, enantioselective haloborylation reaction through the innovative application of chiral anion phase-transfer (CAPT) catalysis to electrophilic-induced boronate rearrangements. Beyond the development of an orthogonal approach towards the formal trifunctionalization of alkenes, the proposed methodology provides easy access to biologically and synthetically important products, and is anticipated to have great impact in the area of diversity oriented synthesis.", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["744604"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Increasingly Anthropogenic Landscapes and the Evolution of Plant-Food Production: Human - Environment Interactions during the Final Pleistocene and Early Holocene in the Levant."], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["H-E Interactions"], "Technology_Description": "H-E Interactions will investigate how increasingly anthropogenic wetland landscapes and the reliable resources therein influenced the evolution of plant-food production and the origins of agriculture through the Final Pleistocene into the Early Holocene (ca.23-8 ka cal. BP). It will consider how earlier human-environment interactions shaped this key transition, integrating the latest theoretical Human Niche Construction (HNC) perspectives with environmental archaeology to investigate 5 well-excavated wetland oriented archaeological sites in the S. Levant. It will employ an interdisciplinary, combination of microbotanical approaches, (phytolith, starch and microcharcoal analyses) and geoarchaeology, in particular micromorphology, to investigate the on- and off-site contexts of a temporally broad set of sites to provide long-term, direct evidence of ancient plant-use. To achieve this, training in geoarchaeology, GIS and multivariate statistical skills will facilitate the production, management and interpretation of the large environmental dataset. As well as providing direct evidence of plant-use and environment from a critical H-E threshold, H-E Interactions is the first study in the region to directly examine how HNC practices impacted the origins of agriculture. So far, the origin of agriculture has been largely understood as a consequence of human reactions to environmental push & pull factors. This project presents an alternative approach and takes the view that increased use of \u2018low-ranked\u2019 resources may reflect deliberate human modification, management and/or food processing innovation, increasing the relative abundance and ease of acquisition of \u2018low-ranked\u2019 resources, resulting in \u2018upward mobility\u2019 of that resource. HNC provides a new way to consider changing plant resource selection in the Levant and the wider cultural and environmental implications, which may have impacted the rise of increasingly sedentary lifestyles and the origins of agriculture.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["743544"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITEIT LEIDEN", "UNIVERSITEIT LEIDEN"], "EU_Contribution": ["EUR 1 499 578"], "Project_Title": ["The Linguistic Roots of Europe's Agricultural Transition"], "Total_Cost": ["EUR 1 499 578"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["EUROLITHIC"], "Technology_Description": "Today, Europe\u2019s linguistic landscape is shaped almost entirely by a single language family: Indo-European. Even by the dawn of history, a patchwork of Indo-European subgroups, Germanic, Celtic, Italic, Baltic, Slavic and Greek, was covering the continent, and over the centuries, these subgroups evolved into the modern European languages, among which Russian, Italian, German, Lithuanian and Swedish, as well as the global lingua francas French, Spanish, and English.", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["716732"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN", "LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN"], "EU_Contribution": ["EUR 146 130"], "Project_Title": ["A clinical phonetics laboratory service (PhonLab): diagnostics of speech impairment via the web"], "Total_Cost": ["EUR 146 130"], "Country": ["Germany", "Germany"], "Project_ACR": ["PhonLab"], "Technology_Description": "In line with present trends to expand eHealth in medical care, this project\u2018s objective is to provide a commercial web-based service for the automatic diagnosis of impaired speech, given a sample of the client\u2019s speech transmitted over the internet. Currently, speech therapists are required to diagnose speech impairments from only a pen and paper analysis of transcriptions based on auditory impressions. The main advantage of the innovative approach of this project is to quantify the production of speech in time according to the scientific state of the art, which is well beyond the scope of presently used impressionistic, auditory techniques. ", "To": ["2018-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["737552"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 2 038 120"], "Project_Title": ["ConfocAl Microscopy and real-time Rheology of dynamIc hyroGels"], "Total_Cost": ["EUR 2 038 120"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["CAM-RIG"], "Technology_Description": "Hydrogels cross-linked through supramolecular interactions are highly dependant on the dynamic charac- teristics of the physical cross-links. Few fundamental studies have been undertaken to quantitatively de- scribe structure-property relationships for these types of systems. Hydrogels formed from CB[8]-mediated supramolecular physical cross-linking mechanisms have gained significant interest on account of their excel- lent physical and mechanical properties such as self-healing and shear-thinning. This supramolecular motif has been further exploited to introduce and compatibilise a wide variety of different materials into hydrogel networks without phase separation, forming hybrid composite hydrogels attributed with unique and emergent properties. This proposal aims to pioneer the combination of several state-of-the-art characterisation tech- niques into an unique experimental setup (CAM-RIG), which will combine super-resolution and confocal microscopy imaging modalities with simultaneous strain-controlled rheological measurements to investigate fundamental structure-property relationships of these systems. For the first time it will be possible to decon- volute the molecular-level dynamics of the supramolecular physical cross-links from chain entanglement of the polymeric networks and understand their relative contributions on the resultant properties of the hydrogels. Using the fundamental insight gained, a set of key parameters will be determined to maximise the potential of supramolecular biocompatible hydrogels, driving paradigm shifts in sustainable science and biomaterial applications through the precise tuning of physical properties.", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["726470"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["STICHTING KATHOLIEKE UNIVERSITEIT", "STICHTING KATHOLIEKE UNIVERSITEIT"], "EU_Contribution": ["EUR 2 498 076"], "Project_Title": ["Encoding information into polymers"], "Total_Cost": ["EUR 2 498 076"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["ENCOPOL"], "Technology_Description": "The amount of information trafficking internet nowadays is enormous and will increase further in the near future. It can be expected that in the next decennia the current technologies to store and process data will no longer suffice and that other strategies to handle information have to be developed. One approach is to explore chemical routes, which nature has also followed during evolution: our brain can store and handle very large amounts of data and process them in a way silicon-based computers cannot do. Although brain-like chemical computers are still far beyond reach, it is of interest to explore how atom and molecule-based systems that can write, read, and store information might be designed and constructed. In this proposal we aim at developing a new technology to write, store, and read information, i.e. on a single polymer chain with the help of a molecular machine that is inspired by the hypothetical device (Turing machine) proposed by the British mathematician Alan Turing in 1936 as the general basis for the operation of a computer. The molecular machine is composed of a chiral catalytic cage compound (tape-head) that moves unidirectionally along a chiral polymer chain (tape) while writing a binary code in the form of (R)- (symbol 0) and (S)- (symbol 1) epoxide functions. This writing process is controlled by light or electrons. The information on the tape will be read by single molecule spectroscopy using a reading device that is also based on a chiral cage compound. It moves along the encoded tape and produces left- or right-handed polarized fluorescence light depending on whether it reads a 0 (R-epoxide) or 1 (S-epoxide). As part of this project we will also make the first steps towards chemical computing by arranging two circular tapes (one left-handed and the other one right-handed), each with an attached writing head, in a teller set-up, which allows them to be addressed separately with light according to a set of instructions (Minsky machine).", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["740295"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 1 996 250"], "Project_Title": ["ARCTIC CULTURES: SITES OF COLLECTION IN THE FORMATION OF THE EUROPEAN AND AMERICAN NORTHLANDS"], "Total_Cost": ["EUR 1 996 250"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["ARCTIC CULT"], "Technology_Description": "The Arctic has risen to global attention in recent years, as it has been reconfigured through debates about global environmental change, resource extraction and disputes over sovereign rights. Within these discourses, little attention has been paid to the cultures of the Arctic. Indeed, it often seems as if the Circumpolar Arctic in global public understanding remains framed as a 'natural region' - that is, a place where the environment dominates the creation of culture. This framing has consequences for the region, because through this the Arctic becomes constructed as a space where people are absent. This proposal aims to discover how and why this might be so.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["724317"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Development of a model system to study the role of chromatin factors during transgenerational epigenetic inheritance (TEI) in C. elegans"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["TEI"], "Technology_Description": "Non DNA-sequence based inheritance has been observed in many organisms from microbes to man and likely impacts public health. The mechanisms of non DNA-sequence based inheritance remain largely unknown. However, some examples of non DNA-sequence based inheritance in mammals, plants and invertebrates are linked to the control of selfish, transposable elements in the genome. Here we propose to discover the mechanistic basis of multi-generational non DNA-sequence based inheritance, also referred to as transgenerational epigenetic inheritance (TEI), using the laboratory animal model Caenorhabditis elegans. Specifically, our goal is to identify chromatin and non-coding RNA \u201cepigenetic\u201d marks that transfer information from generation to generation in C. elegans. C. elegans is a great model for this work as it has a generation time of only three days, has a powerful genetics toolkit and its chromatin and RNA pathways are largely conserved in humans. Towards this goal we have established a novel assay we named piRNA-related insertional chromatin immunoprecipitation (piChIP). Using this piChIP system, our specific aims are:", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["747666"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN", "UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN"], "EU_Contribution": ["EUR 1 997 132"], "Project_Title": ["Labour Politics and the EU's New Economic Governance Regime"], "Total_Cost": ["EUR 1 997 132"], "Country": ["Ireland", "Ireland"], "Project_ACR": ["European Unions"], "Technology_Description": "Trade unions play a major role in democratic interest intermediation. This role is currently threatened by the increasingly authoritarian strain in EU\u2019s new economic governance (NEG). This project aims to explore the challenges and possibilities that the NEG poses to labour politics. Until recently, European labour politics has mainly been shaped by horizontal market integration through the free movement of goods, capital, services and people. After the financial crisis, the latter has been complemented by vertical integration effected through the direct surveillance of member states. The resulting NEG opens contradictory possibilities for labour movements in Europe.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["725240"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["A droplet microfluidic system for continuous in vivo evolution."], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["DropContEvo"], "Technology_Description": "Droplet microfluidics has recently become one of the breakthrough technologies for high throughput screening in microbiology and biochemistry, including single cell studies and new approaches to in vitro evolution. Here we propose a development of a novel microfluidic system for unsupervised execution of multiple cycles of in vivo continuous evolution in hundreds of thousands of picoliter droplets. Each evolutionary cycle will comprise: i) encapsulation of single bacteria cells in water-in-oil compartments ii) growth of the cells coupled with production of economically relevant biomolecules iii) selection of the most efficient populations using ultra-high-throughput sorting of picodroplets, iv) dilution of each population via merging with 100 times larger nanoliter droplet containing fresh nutrients and v) passive splitting of each of the resulting nanoliter droplets to the libraries of picoliter droplets containing single cells. Confinement of the reaction in small volume and active sorting of droplets will facilitate and accelerate the process of in vivo evolution. Droplet format will also enable for various screening schemes, so far not available for continuous evolution strategies \u2013 e.g. based on high throughput fluorescence or absorbance measurements of the droplet content. The second stage of the project will comprise a series of proof-of-concept experiments presenting directed continuous evolution of the tryptophan synthase (TrpS) in E.coli bacteria. The technology proposed here would be very useful for broad community of biotechnologists, evolutionary biologists and industrial specialists without the experience in microfluidics. The proposed research will be conducted at Dr. Hollfelder\u00b4s laboratory that specializes in directed evolution of enzymes and application of microfluidics to industrial biotechnology. The project comprise broad and extensive training in research and complementary soft skills that will aid professional development of the Beneficiary.", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["750772"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Disentangling amygdala contributions to replay-mediated, hippocampal-dependent memory consolidation"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["VALENCE-REPLAY"], "Technology_Description": "In today\u2019s societies, adequate rest takes second place to busy professional and personal schedules. It is known that lack of rest and sleep affects mental health, emotional regulation and daytime function. Such symptoms translate to increased healthcare costs and losses in workplace productivity. How emotional regulation processes interact with sleep and associated memory consolidation functions is not well understood. In addition to increasing basic understanding of brain function, addressing this knowledge gap can help shape therapeutic approaches for mental wellbeing and contribute to EU\u2019s H2020 goals of smart, sustainable and growth. ", "To": ["2019-10-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-15"], "Project_ID": ["746778"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF SOUTHAMPTON"], "EU_Contribution": ["EUR 257 017,35"], "Project_Title": ["Developing methods to model local area temporal domestic electricity demand"], "Total_Cost": ["EUR 257 017,35"], "Country": ["United Kingdom"], "Project_ACR": ["Spatialec"], "Technology_Description": "The objective of this proposal is to implement a programme of research and impact activities intended to provide a step change in the level of understanding of, and modelling capacity for, spatially disaggregated temporal domestic electricity demand in a smart grid and demand response context. This programme will be developed in partnership with internationally recognised experts led by the University of Otago (host) who are pioneering in this field. It will be exploited via an applied research programme at the University of Southampton (beneficiary) which intends to integrate census, social science time use and detailed consumption data to develop local area level demand response models to support the analysis of a range of demand response scenarios. In so doing the fellowship will provide the applicant with a foundation from which to build a new career pathway by applying his substantial existing social scientific data analysis and spatial microsimulation expertise to the development and leadership of a substantial new European research capacity in an area of emerging commercial, societal and political significance.", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["700386"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["FUNDACIO INSTITUT D'INVESTIGACIO SANITARIA PERE VIRGILI (IISPV)"], "EU_Contribution": ["EUR 257 191,20"], "Project_Title": ["Interplay between genetic determinants of glycaemia, type 2 diabetes and cardiovascular disease in interaction with dietary and lifestyle factors"], "Total_Cost": ["EUR 257 191,20"], "Country": ["Spain"], "Project_ACR": ["INTERPLAY"], "Technology_Description": "Genome-wide association studies (GWAS) for complex traits, including glycaemia, type 2 diabetes (T2D) and coronary heart disease (CHD) have been successful in identifying genetic variants associated with those phenotypes. However, they explained only a small proportion of the estimated heritability. Possible reasons include the interplay between genetics and lifestyle determinants, small-effect variants, structural variations and the difficult to characterize non-coding functional variants that interact with other genetic regions. This proposal, in a new era of precision medicine, englobes the systematic study of the interplay between genetic variants associated with glycaemia, T2D, CHD and dietary and lifestyle factors. We propose to conduct a comprehensive analysis of gene and gene-lifestyle interaction, including the existing international GWAS consortia of CARDIoGRAM, DIAGRAM, MAGIC, the U.S. based DPP clinical trial, and the European-wide networks of EPIC-InterAct and PREDIMED. We will test hypothesis about: 1) whether genetically driven hyperglycaemia increases risk of CHD, 2) the association between genetic determinants of CHD and intermediate metabolic phenotypes, and 3) whether dietary components and lifestyle changes influence these associations. Finally, we will extend and replicate these previous results in two independent populations, and to deploy a new method to identify implicated biological pathways. Information that will emerge from that project will provide valuable insights into missing heritability for T2D and CHD. Specifically we expect to uncover genetic determinants for faster CHD progression in T2D, identifying vulnerable individuals who are more likely to experience a differential response to current prevention strategies and to validate potential targets and avenues for intervention. The experienced researcher will emerged from the project with new skills, and the capability to launch his own research group in Europe.", "To": ["2020-02-17, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-02-18"], "Project_ID": ["703787"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["The Remote Control of Maternal Metabolism by the Placenta"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["PlaEndo"], "Technology_Description": "During pregnancy many physiological changes occur in the mother that are designed to support fetal growth. These include changes in the cardiovascular, pulmonary, immune and metabolic systems. In particular, the mother becomes less reactive to insulin, leading to increased glucose availability to the fetus in late pregnancy. These adaptations are thought to be signaled, in part by changes in placental hormone production. Whilst studies have shown that the placenta has the capacity to produce different hormones, their specific role in adapting maternal metabolism during pregnancy relies principally on association studies. Moreover, there are likely to be more protein mediators secreted by the placenta with systemic actions in the mother. Failure to adjust the mother's body to the pregnant state may result in pregnancy complications, including abnormal birth weight and maternal diabetes, which can further lead to a range of medical complications for the mother and baby. The overall goal of this study will be to identify the nature and wider biological significance of placental endocrine function in adapting the mother's body during pregnancy to support fetal growth, with a focus on maternal metabolism. This work will primarily use the mouse as an experimental model as the placental signaling/secreting cells are conveniently organized into a distinct region and are under unique genetic control. Therefore placental signaling cells can be isolated, cultured and genetically-modified independent of other cells in the mouse placenta. The secreted placental candidates will be identified using the latest sequencing technologies, and their metabolic effects will be tested on cell lines and in the whole organism using unique genetic tools available at the University of Cambridge. Knowledge gained from this study will be the first step in the development of targeted interventions for optimizing fetal growth and preventing pregnancy complications.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["703160"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["STICHTING KATHOLIEKE UNIVERSITEIT"], "EU_Contribution": ["EUR 242 929,80"], "Project_Title": ["A Cross-Species Investigation of Memory Replay During Reconsolidation"], "Total_Cost": ["EUR 242 929,80"], "Country": ["Netherlands"], "Project_ACR": ["ReconsolidationDynamics"], "Technology_Description": "A primary treatment for anxiety disorders is exposure therapy, which is based on the principles of extinction, but has the drawback that fear can return. This risk of relapse highlights a need for treatments that persist. Research on reconsolidation has shown that upon reactivation old fear memories can be updated, preventing the return of fear. However, studies targeting reconsolidation to reduce fear have reported mixed results because its boundary conditions are poorly understood. To live up to its clinical potential it is necessary to understand how to most effectively utilize paradigms targeting reconsolidation. The proposed research attempts to address this issue by providing a neural measure of the reconsolidation process itself. This will be achieved by determining whether dynamic patterns of neural network activity that occur during initial learning re-occur during offline \u2018rest\u2019 periods, and test whether this \u2018replay\u2019 of memory is linked to reconsolidation. The first objective of this grant application is to identify and quantify a neural marker of reconsolidation that predicts the absence of fear recovery. During the outgoing phase these questions will be addressed employing an innovative cross-species (humans, rats) approach using similar behavioural tasks, complementary recording techniques (functional magnetic resonance imaging, multi-unit recordings) and state-of-the-art analyses methods. Acquired knowledge and experience will be applied during the return phase where the second objective is to use this neural marker to determine how context serves as one critical boundary condition to inducing reconsolidation. Findings will significantly advance fundamental understanding of reconsolidation and have important implication for applied and preclinical psychiatric research.", "To": ["2018-05-31, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-06-01"], "Project_ID": ["659221"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["GRAN SASSO SCIENCE INSTITUTE"], "EU_Contribution": ["EUR 180 277,20"], "Project_Title": ["Galactic cosmic RAy Propagation: an Extensive Study"], "Total_Cost": ["EUR 180 277,20"], "Country": ["Italy"], "Project_ACR": ["GRAPES"], "Technology_Description": "Where do Cosmic Rays (CRs) originate? How do CRs interact with the environment during their journey to Earth?", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["751311"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["Barcelonabeta Brain Research Center Foundation"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Multiregional rtfMRI Neurofeedback for the Prevention of Alzheimer's Disease"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["NPAD"], "Technology_Description": "This project aims at predicting early cognitive decline using a neurofeedback performance endophenotype based on realtime functional magnetic resonance imaging in a population at risk for Alzheimer\u2019s Disease (AD). It has been proven that AD biomarkers change decades before the development of symptoms. In addition, there is a lack of robust hypersensitive methods capable of predicting impending cognitive decline in healthy subjects at risk. This constitutes a crucial obstacle for the implementation of AD prevention trials. To address this, we will identify and characterize a novel neurofeedback performance endophenotype in a subsample from a cohort of 2743 cognitively healthy volunteers at risk for AD. This will be based on state-of-the-art neuroimaging technology, in combination with a novel sensitive neuropsychological test that detects subtle alterations in episodic memory, which has been validated for our cohort. Then, we will evaluate the impact on our newly developed neurofeedback performance endophenotype of factors known to be related to AD such as various clinical and lifestyle variables, amyloid deposition, genetic background (including, but not restricted to APOE4) and most importantly cognitive reserve. A specific aim is to test the hypothesis that neurofeedback performance can become a reliable proxy to measure cognitive reserve. Finally, we will develop a novel statistical predictive model, featuring all the relevant genetic and clinical variables and will assess the capacity of neurofeedback performance for predicting impending cognitive decline during a two-year period in AD descendants.", "To": ["2018-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2016-05-01"], "Project_ID": ["707730"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITY OF YORK", "UNIVERSITY OF YORK"], "EU_Contribution": ["EUR 1 989 611"], "Project_Title": ["The evolutionary and developmental origins of Joint Attention: a longitudinal cross-species and cross-cultural comparison"], "Total_Cost": ["EUR 1 989 611"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["JOINTATT"], "Technology_Description": "Humans frequently coordinate and share attention about objects and events. Our basic ability to engage in joint attention (JA) is thought to underpin our uniquely complex cooperation skills and language, raising the possibility that the emergence of JA was a \u2018small change that made a big difference\u2019 in the evolution of human cognition. Despite the theoretical importance of JA for understanding human social cognition, we know surprisingly little about JA across species and cultures. Methodological shortcomings limit our understanding of the extent to which JA is uniquely human or shared with our primate cousins, and we lack data on how this ability develops in non-western cultures, which aspects of the social environment are necessary for JA to emerge and how JA is related to the emergence of cooperation. The JOINTATT project will address these four key issues by collecting longitudinal data on mother-infant dyads over the first 2 years of the infant\u2019s life, across four different study groups: Ugandan and British humans; wild chimpanzees and crested macaque monkeys. The project will develop novel tasks and measures that allow the same set of data to be collected in directly comparable ways across species and provide the first valid, rigorous test of whether engagement in JA is a uniquely human trait. Data from the two human groups will test how different elements of JA are related and whether JA develops in a uniform way across cultures. Longitudinal data on mother-infant interactions and the infant\u2019s environment will be related to performance on JA tasks across all four groups, enabling us to identify conditions that are likely necessary for JA to emerge. Performance on JA and cooperative tasks will be compared to assess whether engagement in JA predicts the later emergence of cooperation. This project will provide ground-breaking insights into JA and its evolutionary origins, and is likely to challenge current theories of how human social cognition evolved.", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["724608"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITE GRENOBLE ALPES", "UNIVERSITE GRENOBLE ALPES"], "EU_Contribution": ["EUR 2 454 367,50"], "Project_Title": ["The Dawn of Organic Chemistry"], "Total_Cost": ["EUR 2 454 367,50"], "Country": ["France", "France"], "Project_ACR": ["DOC"], "Technology_Description": "Terrestrial life is based on organic chemistry, on the complex combination of relatively small molecules containing less than 50 atoms of carbon and other elements in smaller quantities. Some of these bricks, notably amino acids, are found in meteoritic and cometary material, a fact (among others) which led the Nobel laureate C. de Duve to conclude that \u201cthe seeds of life are universal\u201d and \u201clife is an obligatory manifestation of matter, written into the fabric of the Universe\u201d.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["741002"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["LUNDS UNIVERSITET", "LUNDS UNIVERSITET"], "EU_Contribution": ["EUR 2 498 625"], "Project_Title": ["Hunting for the elusive \u201csixth\u201d sense: navigation and magnetic sensation in a nocturnal migratory moth"], "Total_Cost": ["EUR 2 498 625"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["MagneticMoth"], "Technology_Description": "Many animals \u2013 including birds, sea turtles and insects \u2013 perform spectacular long-distance migrations across the surface of the Earth. Remarkably some, like birds, can accurately migrate between highly specific locations thousands of kilometres apart, a navigational feat that requires an external compass cue and a robust sensory system to detect it. The Earth\u2019s magnetic field is one such compass cue. But exactly how the magnetic field is sensed, and which receptor cells are involved, remains a mystery and its discovery is one of the greatest \u201choly grails\u201d in modern sensory physiology, and also the main aim of this proposal. Fortuitously, I have made a pioneering discovery that a migratory insect \u2013 the Australian Bogong moth \u2013 relies on the Earth\u2019s magnetic field to navigate at night. Due to its tractable nervous system, this insect may thus hold the key to uncovering the identity of the enigmatic magnetosensor. By tethering flying migrating moths in a flight simulator, I will dissect for the first time how insects use magnetic cues to navigate, isolating which of the two current (contentious) hypotheses for magnetic sensation apply. The most likely of these involves the action of photoreceptor-based cryptochrome (Cry) molecules in the eyes. Having cloned genes for 4 visual opsins and 2 Cry in Bogong moths, I will use in situ hybridisation to localise putative magnetoreceptors in the eyes, targeting them with intracellular electrophysiology and magnetic stimulation in an attempt to describe the physiology of these elusive sensors for the first time. The project is ground breaking since it will elucidate how a migratory insect, despite its small eyes and brain, detects and uses the Earth\u2019s magnetic field for navigation. The discovery of the enigmatic magnetoreceptor would be a sensation, opening the floodgates for international research on this little understood sense.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["741298"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["SENSARS NEUROPROSTHETICS SARL"], "EU_Contribution": ["EUR 99 912,50"], "Project_Title": ["Restoring of SENSAtions from Lost LeGs for health And qualIty of life augmeNtation in amputees"], "Total_Cost": ["EUR 99 912,50"], "Country": ["Switzerland"], "Project_ACR": ["SensAgain"], "Technology_Description": "During the FET NEBIAS we developed and clinically validated novel and effective restoration of sensory feedback from missing hand in upper-limb amputees. They felt natural sensations, used to ameliorate control and acceptance of prosthesis, and diminish phantom limb pain. The goal of SensAgain is to exploit these results commercially. In particular, we aim at verifying whether the innovation generated during NEBIAS could be used to provide valuable device for lower-limb amputees. We target them because they represent a larger population and suffer health problems related to absence of sensations from prosthesis. Indeed, because of the lack of sensory feedback from available prostheses, they suffer: falls due to unexpected perturbations, asymmetric walking and balance which induce arthritis, osteoporosis and back pain, higher power consumption (with occasional hearth failures), feeling the prosthesis as a foreign body (with consequent abandonment) and phantom pain. The first step we will perform is the validation with market stakeholders, which will enable the identification of the minimum features of a product accepted by the market, and the development of a strategic partnership with manufacturers, which will speed up the realization of a device compliant with CE standards. Then, we will define a clear market penetration strategy. Together with providing disabled persons with a unique device for rehabilitation, SensAgain will boost prosthetic adoption, with the consequent growth of the prosthetics and rehabilitation industries, which at its turn will create new jobs. Finally, by sharing the results with the members of the NEBIAS consortium, we will train academia personnel to structure their research mind-set toward the resolution of problems tailored by the market needs. On the other hand we will favor the process of creating innovation in industry, offering job positions to people with a background in research, in case of success of our translational project.", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-04-2016-2017 - FET Innovation Launchpad"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Switzerland"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-09-01"], "Project_ID": ["754497"], "Call_for_Proposal": ["H2020-FETOPEN-4-2016-2017"]}, -{"Partners": ["UNIVERSITA COMMERCIALE LUIGI BOCCONI", "UNIVERSITA COMMERCIALE LUIGI BOCCONI"], "EU_Contribution": ["EUR 1 375 869"], "Project_Title": ["Explaining Politicians' and Voters' Behavior"], "Total_Cost": ["EUR 1 375 869"], "Country": ["Italy", "Italy"], "Project_ACR": ["POLITICALMIND"], "Technology_Description": "Theoretical models and empirical studies in political economy aim at explaining both the beliefs and the choices of voters and politicians, so as to assess their impact on economic policy. In particular, a recent literature has recognized the crucial relevance of the identity of politicians in taking policy decisions and ultimately in shaping the fate of their country (Besley 2005; Jones and Olken 2005). In this project, we will address two neglected elements in the existing literature: the role of political parties as organizational structures that shape political careers (i.e., who gets on top in democracies); and the nature of social preferences, personality traits, and cognitive biases in understanding the beliefs and the choices of both politicians and voters.", "To": ["2021-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["648833"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["FACULDADE DE ARQUITETURA DA UNIVERSIDADE DE LISBOA (UL)"], "EU_Contribution": ["EUR 160 635,60"], "Project_Title": ["3D SMART MODELS FOR HERITAGE CONSERVATION An Open Science project for documentation, management and representation of Cultural Heritage"], "Total_Cost": ["EUR 160 635,60"], "Country": ["Portugal"], "Project_ACR": ["3D-SMoHC"], "Technology_Description": "In today\u2019s society, three-dimensional models of the tangible heritage present the greatest potential for heritage conservation efforts, due to advances in display devices, capabilities, and infrastructure costs, etc. However, in reality, these models do not always provide the necessary accuracy; they require an arduous process of managing and transforming; and they are not set up for reuse and long-term archiving. Without such capabilities we are left with inadequate knowledge that leads to higher expenses and time costs during documentation of fieldwork, disconnected bodies of geospatial data, and over-dimensioned and disorganised information. These problems further limit the scope and efficiency of the use of digital heritage resources for professionals, and restrict the accessibility of these resources to a wider audience without technical literacy, therefore constraining conservation and reuse practices throughout society. ", "To": ["2019-06-04, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Portugal"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-05"], "Project_ID": ["747046"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF BRIGHTON"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["The Impact of Intangible Cultural Heritage (ICH) in formal, non-formal and informal education and its contribution to the Key Competences for Lifelong Learning in the EU Reference Framework"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ICH-Bildung"], "Technology_Description": "Europe\u2019s Intangible Cultural Heritage \u2013 the skills, music, dance, drama, gastronomy, festivals, crafts, etc which have been passed from one generation to the next \u2013 is a hugely important economic and social resource. Yet this aspect of cultural heritage is poorly researched. \u2018ICH-Bildung\u2019 proposes to redress that balance and study the Impact of Intangible Cultural Heritage (ICH) in formal, non-formal and informal education and its contribution to the Key Competences for Lifelong Learning in the European Reference Framework.", "To": ["2017-04-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-05-01"], "Project_ID": ["661385"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE QUEEN'S UNIVERSITY OF BELFAST"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["A ductile, high energy absorptive and rapid post-tensioning system for extending life of concrete structures"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SMArtPlate"], "Technology_Description": "Extending the service life of reinforced concrete structures not only represents an economical advantage to owners, but also significantly contributes to the sustainability of the built environment, through the saving of natural resources and reduction of green gas emissions. In view of the shortcomings of the most commonly used strengthening techniques, such as FRP systems, the state of the structural retrofitting art demands a robust retrofitting solution feasible of rapid installation and easy post-tensioning applications along with a high energy dissipation capacity (e.g. independently of the quality and thickness of concrete cover, no need of mechanical devices for the post-tensioning applications and an adhesive free connection system) for specific cases such an strengthening against earthquake, impact and blast due to either accidents or terrorist attacks. This product-oriented proposal aims to develop an innovative element, herein after designated SMArtPlate to meet these requirements. Such a thin prefabricated plate will be precisely tailored to utilize the synergistic advantages of two advanced materials for the retrofitting of RC structures: ductile fiber reinforced geopolymer mortar and shape memory alloys (SMA). Following an interdisciplinary approach, experimental and numerical investigations will be conducted to develop and assess strengthening performance of the SMArtPlate.", "To": ["2019-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["753903"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Rational design of novel heterometallic MOFs for their use in heterogeneous catalysis for cascade reactions"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["hetero-MOF"], "Technology_Description": "\"The field of metal-organic frameworks (MOFs) is currently among the most extensively studied topics in chemistry given the large number of fascinating applications associated with the chemical versatility of MOFs. In particular, the use of MOFs as heterogeneous catalysts is an area that has attracted considerable attention since, in principle, the ideally suited architectures of MOFs can present catalytically active sites spatially arranged. With the expansion of this area, a new emergent class of heterometallic metal-organic frameworks (hetero-MOFs) has recently been considered for the study of an important type of reactions from an industrial point of view in which two or more individual reactions are carried out in a single step (\"tandem\" or \"cascade\" reactions). However, the synthetic approach for the preparation of these hetero-MOFs has been mainly conducted by post-synthetic replacement of ions with the same oxidation state, with lack of control over the final composition.", "To": ["2017-04-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2015-05-01"], "Project_ID": ["658224"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["FUNDACION IMDEA MATERIALES"], "EU_Contribution": ["EUR 85 060,80"], "Project_Title": ["Characterization and Modelling of dislocation-INterface Interactions in MetAllic Laminates at multiple scales"], "Total_Cost": ["EUR 85 060,80"], "Country": ["Spain"], "Project_ACR": ["MINIMAL"], "Technology_Description": "The global market will increase from $11 billion in 2012 to $22.5 billion in 2018 for micro electro mechanical systems (MEMS), and from $1.9 billion in 2012 to $6.6 billion in 2018 for BioMEMS. Recently, metallic nanolaminates have attracted application as mechanical parts in MEMS and BioMEMS manufacturing. This is due to their superior properties, i.e. large flow strength, high indentation hardness, excellent ductility, good radiation damage resistance, qualified electrical/magnetic response, and promising fatigue/failure resistance. In order to address the performance of metallic nanolaminates and to reduce materials\u2019 failure and cost under different service conditions, better analysis/predictive tools are required for dislocation-interface interactions. The improved analysis/predictive tools will allow designing more advanced nanolaminate materials. However, to develop such analysis/predictive tools, it entails (a) in-depth understanding of the physical mechanisms behind dislocation-interface interactions, (b) accurate in-situ mechanical testing data at different length scales from micro- to nanometers, and (c) efficient numerical modelling to predict dislocation-interface interactions. Through this Marie Sk\u0142odowska-Curie action, we will contribute significantly towards improving these analysis/predictive tools from two aspects, including (i) providing the scientific knowledge behind dislocation-interface interactions, and (ii) establishing improved numerical models to predict dislocation-interface failure during service. Meanwhile, the new advanced nanolaminate materials with enhanced properties will also be proposed based on the generated knowledge. In addition, the researcher and the host organization will benefit from the two-way transfer of knowledge between them.", "To": ["2019-04-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2018-05-01"], "Project_ID": ["749192"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Evaluation of three-dimensional velocity field, mixing field, and flame-front in a model gas turbinecombustor"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["3DFlameGT"], "Technology_Description": "As noted by European turbine network, gas turbine is and will remain dominant mode of energy conversion. An advanced experimental study of a model gas turbine combustor is proposed. The lasers play indispensable role in the experimental combustion research due to the associated non-intrusive nature. The laser diagnostics have evolved from a point measurement to planar measurement (2D) over the years. The objective of the present work is to develop novel laser diagnostics to deduce instantaneous 3D fields of the flow, air/fuel mixing, and flame-front topology in a 'volume'. The proposed technique will be applied to a model gas turbine combustor operating with and without combustion instability. A scanning stereoscopic Particle Image Velocimetry (flow field) and Laser Induced Fluorescence of CH2O radical (flame-front) and of fuel concentration will be assembled correlated with pressure traces. A 4 head Nd:YAG laser cluster will generate 4 parallel laser sheets separated in space and images will be recorded by high speed cameras. The novel use of laser cluster ensures high pulse energy and temporal resolution. Image processing will be developed to reconstruct the 3D fields from the planar slices. The approach will be validated in a Bunsen burner before applying it to swirl stabilized flames that mimic a typical gas turbine combustor. The technology readiness level (TRL) of the research will reach between TRL 3 to 4. The proposed research will diversify the skill set of the researcher and associated complementary training will ensure that the fellow becomes an established academic researcher. The impact of this work is the generation of a unique 3D flame database, which is of great importance for the understanding of turbulent flame-flow interaction and the evaluation of advanced numerical combustion models. Thus, the proposed research will enhance European competitiveness in gas turbine design and can have an impact on automotive engine development.", "To": ["2020-01-01, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-02"], "Project_ID": ["747576"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSIDAD DE BURGOS"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Molecular to Continuum Investigation of Anisotropic Thermal Transport in Polymers"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["MCIATTP"], "Technology_Description": "In 2014, EU PLASTICS INDUSTRY accounted for 1.4MM jobs and contributed to high living standards of the EU citizens by enabling new and more affordable technologies. Most of the PROCESSING of POLYMERIC MATERIALS occurs under NON-ISOTHERMAL flow conditions. As a result, the COST/ENERGY REQUIRED to manufacture, recycle and dispose polymers is STRONGLY AFFECTED by the thermo-physical properties linkage to state variables such as temperature and stress. Experiments show that flowing polymers exhibit ANISOTROPIC THERMAL CONDUCTIVITY (ATC) (i.e. direction dependent). This phenomenon has been previously NEGLECTED in both the simulation of INDUSTRIALLY relevant flows and the development of a molecularly-based THEORY for thermal transport in polymers. ", "To": ["2019-10-15, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-16"], "Project_ID": ["750985"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITETET I BERGEN", "UNIVERSITETET I BERGEN"], "EU_Contribution": ["EUR 2 413 371"], "Project_Title": ["Perception of voices that do not exist: Tracking the temporal signatures of auditory hallucinations"], "Total_Cost": ["EUR 2 413 371"], "Country": ["Norway", "Norway"], "Project_ACR": ["ONOFF"], "Technology_Description": "\"One of the most perplexing phenomena of the human mind is the conviction of perceiving a \"voice\" in the absence of an external auditory source. This is called an auditory hallucination (AH), and is the most characteristic symptom of the most severe mental disorder, schizophrenia. Understanding the phenomenology, cognitive, and neurobiological underpinnings of AHs will not only provide new insights for explaining schizophrenia, but will also provide new insights into the \"complexities of the mind\". In my previous research, I have uncovered the neurocognitive markers of the initiation of an AH, focusing on what causes the onset of a hallucinatory episode. The current proposal further narrows the focus, asking a single question; why do AHs spontaneously come-and-go over time, or stated otherwise, why are they not permanently present once initiated? If we believe that the onset of an episode has neurocognitive markers, which all evidence supports, then we must also acknowledge that the offset must have corresponding markers. This question has to my knowledge never been addressed, although it is vital for the understanding of the underlying mechanisms, and for new treatment strategies. I will track the fluctuations of AH episodes in real-time with iPhone app technology, going beyond interview questionnaires. I will track how cognition modulates the onset and offset with an experimental dichotic listening paradigm, going beyond standard tests. I will track what happens in the brain the few seconds before the onset and, in particular the offset of an episode, using component-based fMRI analysis, going beyond \"blobology\". I will track with MR spectroscopy the interaction of excitatory and inhibitory transmitters that are hypothesized to mediate episode onsets and offsets, respectively, going beyond systems imaging. Thus, I will track AH episodes from the clinical to the receptor level, working vertically through a \u201clevels of explanation\u201d model, from higher to lower levels\"", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["693124"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["DATASOUND: Understanding data with sound"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["DATASOUND"], "Technology_Description": "More and more, organizations are generating huge amounts of data, which need to be stored and processed in order to gain useful insights and achieve competitive advantage. While the storage and analysis are nowadays mostly carried out by computers, the interpretation of data is still performed by humans through visual means. ", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["743623"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITA CA' FOSCARI VENEZIA"], "EU_Contribution": ["EUR 250 518,60"], "Project_Title": ["Shifting Dynamics of Chinese Labour in a Global Perspective"], "Total_Cost": ["EUR 250 518,60"], "Country": ["Italy"], "Project_ACR": ["Chinese Labour"], "Technology_Description": "With the financial crisis stepping up the pressure on labour regimes around Europe, and with the European national economies increasingly subject to the vagaries of an uncertain Chinese growth, questions traditionally of interest only to Chinese labour specialists and rights advocates are taking a whole new dimension. Chinese labour issues have ceased to be local matters and have assumed a particular urgency, entering much of the political rhetoric of the European countries. Such diffused presence of Chinese labour in the European imaginary raises many questions and requires a thorough investigation. In particular, in the past few years, much has been written about a \u201crights awakening\u201d allegedly undergoing among internal migrant workers in China. But how do Chinese workers perceive their rights? What role do Chinese state and non-state actors play in shaping this perception? And, more important, how will these shifting dynamics of Chinese labour activism affect the future of China as a \u201cworld factory\u201d? Research that answers these questions is still scarce. The purpose of this study is threefold: a) analyse the expectations of Chinese migrant workers toward work hours and salaries, on the background of the minimum standards mandated by the current labour legislation; b) deconstruct the role played by different actors in shaping these expectation, with a particular attention to the role of the central and local state, the union, civil society organizations and foreign enterprises; c) address the implications of the rising expectations of the Chinese workers for EU investments in China and for the future of the country as a \u201cworld factory\u201d. This research will not only give a meaningful contribution to the academic debate, but will also provide European policy-makers, companies, trade unions and labour NGOs with much needed knowledge on how to address Chinese labour issues in this new phase of the globalization process.", "To": ["2018-12-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-12-15"], "Project_ID": ["654852"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Investigating the role of bacteria-produced siderophores in satisfying diatom Fe requirements."], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["IRONCOMM"], "Technology_Description": "The greatest impact of climate change will be exerted on ocean biomes. In order to mitigate for its effects it is paramount to understand the dynamics of phytoplankton communities within, which are responsible for marine carbon fixation (50% of the of the primary production on Earth). Our current understanding of phytoplankton dynamics is limited \u2013 particularly when linking a molecular level understanding of metabolic processes with ecology. In the proposed work I will investigate the hypothesis that diatoms, which are ubiquitous phytoplankton species across all marine habitats interact with bacteria to acquire bioavailable iron from siderophores produced by the latter. My investigations will address this aim across all scales of biological organization. I will capitalize on preliminary investigations at the host laboratory that have begun to unravel the molecular pathways associated in siderophore acquisition in diatom species. My work will be novel in terms of characterizing the molecular mechanism by which siderophores are transported into and distributed to where required within diatom cells. Further, I will explore the hypothesis that siderophore acquisition is a result of mutualism between bacteria and diatoms. The results will bear important eco-evolutionary consequences to our understanding of microbial communities. Finally, on a global scale, I will quantify the relevance of my findings by mining of metatranscriptomic data collected in global transects of the ocean (specifically during the Tara Oceans expedition). Through this fellowship I will develop a range of new technical skills including novel molecular techniques and bioinformatics, as well as transferable competencies (e.g. using French at work). The fellowship will provide me with an opportunity to return to Europe (from the USA), expanding my academic network of collaborators and putting me in a prime position for applying for faculty positions as a next step in my academic career.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2017-07-01"], "Project_ID": ["748581"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE DE BORDEAUX"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Personal Ornaments in the Palaeolithic of Europe"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["PeOPLE"], "Technology_Description": "The project PeOPLE (Personal Ornaments in the PalaeoLithic of Europe) seeks a new perspective on the archaeological framework for Eastern Europe during the earlier part of the Upper Palaeolithic (UP) by study of the beads and other personal ornaments known from sites of this period. The study period covers ca. 45,000-25,000 years ago \u2013 the first twenty thousand years of modern human occupation of ice age Europe. ", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["747400"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE DE GENEVE"], "EU_Contribution": ["EUR 187 419,60"], "Project_Title": ["Molecular mechanisms of endosome departure from the spindle in asymmetric cell division"], "Total_Cost": ["EUR 187 419,60"], "Country": ["Switzerland"], "Project_ACR": ["ENDODEP"], "Technology_Description": "During mitosis, cells can undergo asymmetric cell division, where daughter cells are endowed with different fates. Asymmetric division enables developing organisms to generate their particular diversity of cell types through a balanced combination of self-renewal and differentiation. Better understanding the mechanisms of asymmetric cell division will shed light on how cell renewal, differentiation and proliferation are controlled. In the longer term, this knowledge might enable regenerating defective cells in ageing and disease, generating cells of a particular identity for therapeutic purposes and tackling cell proliferation in cancer.", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["750335"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["BUREAU DE RECHERCHES GEOLOGIQUES ET MINIERES"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Institutions for Resilient Groundwater Dependent Rural Economies"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["RURECO"], "Technology_Description": "Groundwater is a strategic resource for modern economies worldwide; yet it is over-exploited at an alarming rate. New forms of governance are sought, in particular in rural areas with intensive agricultural irrigation where authorities lack the means to regulate large numbers of dispersed users. During the Fellowship, I will develop new understanding of strategies and institutional arrangements for increasing the resilience of groundwater dependent rural economies, and develop and test a methodology that support local actors to design collective solutions. Overall, the Fellowship aims to: (1) carry out a global assessment of strategies and institutions currently used worldwide; (2) develop a participatory foresight methodology to support the design of innovative strategies and institutional arrangements in two case studies; and (3) promote academic exchange and disseminate research. The Fellowship will enable me to strengthen my empirical and theoretical knowledge of the design of institutions for common-pool resource management and natural resource management, and position me as a leading scholar in the competitive research community on environmental and institutional economics. A carefully crafted series of scientific exchanges and collaborations will expand my outreach to a global level, and open opportunities for new research collaborations. The French Geological Survey (BRGM), France, is the ideal host organisation to carry out this research because of its established expertise on groundwater management with an emphasis on inter-disciplinary research of high societal relevance, and its extensive global networks. I will contribute to BRGM\u2019s current research agenda and strengthen its collaborations in and outside Europe. My research will contribute to Europe\u2019s knowledge base economy by providing new insights to safeguard society against water-related vulnerabilities.", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2018-02-01"], "Project_ID": ["750553"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["QUEEN MARY UNIVERSITY OF LONDON"], "EU_Contribution": ["EUR 183 792,60"], "Project_Title": ["Mechanobiology of METAstatic and DORMant cancer cells in bone marrow lesions"], "Total_Cost": ["EUR 183 792,60"], "Country": ["United Kingdom"], "Project_ACR": ["META-DORM"], "Technology_Description": "While cancer survival rates have improved significantly in recent years, survival decreases dramatically after tumour metastasis. One of the most common sites for metastatic tumours to develop is bone. Intriguingly, evidence suggests that once they have invaded the bone marrow, individual metastatic cancer cells can persist for years in a quiescent or \u201cdormant\u201d state, and are resistant to both radiation and chemotherapy treatment. These dormant cells can reside for months or years while the cancer is in remission, and then \u201creactivate\u201d without warning to form new, usually fatal, skeletal lesions. Tumour cells achieve this by \u201chijacking\u201d the normal bone remodelling cycle, a homeostatic balance between bone formation and resorption, to form a metastatic niche within the marrow. However, the signalling mechanisms that cause metastasis and dormancy, particularly in such a mechanically active environment, are poorly understood. Therefore, the goal of this project is to investigate the chemical and physical interactions between bone and cancer cells, both during dormancy and mechanical stimulation, to provide new insight into bone metastatic lesions and explore novel therapeutic targets to prevent cancer metastasis. This will be achieved by culturing specific bone and cancer cell types together for the first time to observe changes in their signalling and behaviour. Dormancy will also be induced, to observe its effect on changes in signalling. Mechanical stimulation will be applied to investigate whether the complex mechanical environment of the bone marrow plays a role in cancer metastasis. Finally, a specific cellular mechanosensor, the primary cilium, which has been implicated in the development of cancer and is known to be involved in bone formation, will be investigated. This will shed new light on its chemosensing and mechanobiological roles in cancer metastasis, as well as explore its potential as a novel target for cancer treatment and prevention.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["748305"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ANGLIA RUSKIN UNIVERSITY HIGHER EDUCATION CORPORATION"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["ENvironmental COnditions in GLAucoma Patients"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ENCOGLAP"], "Technology_Description": "Glaucoma is a common eye pathology that can lead to blindness. As it is a progressive disease, longer-term treatment is required for its control, based mainly on the regular use of topical eye drops. Adherence to the treatment is the degree to which a patient\u2019s behaviour in taking medication corresponds with agreed recommendations from their doctor. Various risk factors for non-adherence to the glaucoma treatment have been identified, but the role played by an individual\u2019s ocular surface characteristics and the influence of different environmental conditions are not well understood. The objectives of ENCOGLAP (ENvironmental COnditions in GLAucoma Patients) are to determine which ocular surface characteristics and environmental conditions will influence non-adherence to treatment. The influence of preservatives in eye drops will also be investigated. The overarching aim is to provide a guide of \u201crisk factors of non-adherence\u201d that could be used in the clinical practice.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["747441"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KOC UNIVERSITY", "KOC UNIVERSITY"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Augmented Reality Wearable Platform and Screen: Proof of Concept and Commercialization"], "Total_Cost": ["EUR 150 000"], "Country": ["Turkey", "Turkey"], "Project_ACR": ["MIRAGE"], "Technology_Description": "Wear3D display technology project is an ERC-Advanced project and offers novel optical solutions for wearable (or head-mounted) displays to achieve very wide field-of-view and natural-looking 3D. The Wear3D technology has a lot of potential as the global consumer market for AR and VR are expected to reach more than US$30 billion and US$120 billion by 2022, respectively. Hardware devices will be more than 30% of the total market.", "To": ["2018-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Turkey"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["755154"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["CONSORCIO PARA LA CONSTRUCCION EQUIPAMIENTO Y EXPLOTACION DEL LABORATORIO DE LUZ SINCROTRON"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Getting new insights into the radio-sensitization effects of nanoparticles in photon and charged particle therapy"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["NANOCANCER"], "Technology_Description": "The use of high-atomic-number nanoparticles (NP) as tumour radio-sensitizers has been recently proposed as a breakthrough in radiotherapy (RT). Numerous biological studies have shown the enhanced effectiveness in tumor cell killing when NP were associated to photon RT and, more recently, to charged particle therapy. However, the mechanisms of action are not clear yet. In addition to the damage due to a possible local dose enhancement (physical effects), the interaction of NP with essential biological macromolecules could lead to changes in the cells (biochemical effects) leading to an amplified effect of the radiation. Within this framework, the main goal of the NANOCANCER project is to get deeper insights into the mechanisms underlying the amplification of radiation effects of NP. For this purpose, I will use a multidisciplinary strategy to evaluate both the biochemical and physical effects involved in these innovative nano-RT approaches. Vibrational spectroscopy (Fourier transform infrared, FTIR, microspectroscopy) will be employed for the first time to investigate the biochemical features in glioma cells combining two high-Z standard nanoparticles (Au and Gd) and charged particle beams. Physical effects will be also assessed by performing complementary Monte Carlo simulation of radiation transport, which will allow a realistic modelling of early biological damages induced by the radiation at the nanometre scale. This interdisciplinary proposal will be essential to better characterize the radio-sensitization effects of NP in glioma cells and, in addition, will bring light to the present charged particle therapy radiobiology, which seems to lead to substantially different tumour responses with respect to conventional RT at the cellular and molecular level. The knowledge of these biochemical features will help researchers to develop RT by taking full advantage of the underlying biology an enhance the therapeutic index of RT for diseases with poor prognosis.", "To": ["2019-10-29, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-SE - Society and Enterprise panel"], "Coordinated_in": ["Spain"], "Activity": ["Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2017-10-30"], "Project_ID": ["748889"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Light-engaged Accommodating IOL"], "Total_Cost": ["EUR 150 000"], "Country": ["Spain", "Spain"], "Project_ACR": ["Light AIOL"], "Technology_Description": "Presbyopia, the age-related loss of the ability of the eye to focus near and far objects, affects 1.2 billion people in the world. While there are a number of corrections for presbyopia available (near and progressive spectacles, monovision or multifocal lenses) none of these restore the dynamic focusing capability of the young crystalline lens. ", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["754630"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["IPATIMUP - INSTITUTO DE PATOLOGIA E IMUNOLOGIA MOLECULAR DA UNIVERSIDADE DO PORTO PCUP"], "EU_Contribution": ["EUR 148 635,60"], "Project_Title": ["3D glyco-engineered models to address the role of glycosylation in gastric cancer clinical management"], "Total_Cost": ["EUR 148 635,60"], "Country": ["Portugal"], "Project_ACR": ["GlycoModels"], "Technology_Description": "Gastric cancer is an important health problem, being the fifth most common cancer and the third leading cause of cancer death. Its late diagnosis accompanied with a bad prognosis keeps this malignancy among the most deadly. ", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Portugal"], "Activity": ["Research Organisations"], "From": ["2017-05-01"], "Project_ID": ["748880"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE DE TOULOUSE II - LE MIRAIL", "UNIVERSITE DE TOULOUSE II - LE MIRAIL"], "EU_Contribution": ["EUR 2 432 062"], "Project_Title": ["Mapping Ancient PolytheismsCult Epithets as an Interface between Religious Systems and Human Agency"], "Total_Cost": ["EUR 2 432 062"], "Country": ["France", "France"], "Project_ACR": ["MAP"], "Technology_Description": "Writing the history of ancient religions usually starts with the gods, considered as personifications linked by kinship or affinity. Yet this oversimplified approach overlooks the fact that gods are multifaceted powers, not individuals. MAP proposes to exploit the epithets attributed to the gods as the most efficient indicator of their multiple powers and modes of action, as well as their connection to places where humans interact with them. Epithets identify the god(s) invoked and thus enhance the effectiveness of ritual communication. With the great number of combinations produced by epithets, their entire repertoire results in a highly complex system of divine networks.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["741182"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITY OF KENT", "UNIVERSITY OF KENT"], "EU_Contribution": ["EUR 149 300"], "Project_Title": ["Adapter for a commercial grade camera or a smart phone to perform depth resolved imaging"], "Total_Cost": ["EUR 149 300"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["AdaSmartRes"], "Technology_Description": "The proposal refers to a patented adapter that can transform a commercial grade digital camera or the camera in a smart phone into a depth resolved imaging instrument. Several adapters will be assembled, making use of optical coherence tomography (OCT) technology protected by some other of PI\u2019s patents. The activity takes advantage of recent progress in commercial grade cameras in terms of their modes of operation as well as in terms of parameters of their devices, such as sensitivity and speed of their photodetector arrays.", "To": ["2018-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["754695"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["UNIVERSITE PARIS-SUD", "UNIVERSITE PARIS-SUD"], "EU_Contribution": ["EUR 1 263 607"], "Project_Title": ["Brownian geometry: at the interface between probability theory, combinatorics and mathematical physics."], "Total_Cost": ["EUR 1 263 607"], "Country": ["France", "France"], "Project_ACR": ["GeoBrown"], "Technology_Description": "The main purpose of this proposal is to explore the canonical models of planar random geometry that have been introduced in the recent years. We call this theory Brownian geometry because one of the central objects, the Brownian map, arises as the universal scaling limit of many discrete models of large random graphs embedded in the plane, in a way very similar to Brownian motion, which is the continuous limit of many different classes of random paths. The preceding scaling limit holds for the Gromov-Hausdorff distance on compact metric spaces. Furthermore, recent developments show that, in addition to its metric structure, the Brownian map can be equipped with a conformal structure.", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["740943"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITEIT UTRECHT", "UNIVERSITEIT UTRECHT"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Can Limitarianism Be Justified? A Philosophical Analysis of Limits on the Distribution of Economic and Ecological Resources"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["FAIR LIMITS"], "Technology_Description": "In contemporary normative political philosophy, questions of distributive justice have focused on meeting minimal needs of persons, prioritizing the worst-off and reducing inequalities. In philosophy, these views are called \u2018sufficientarianism\u2019, \u2018prioritarianism\u2019 and \u2018egalitarianism\u2019. The proposed project \u2014Fair Limits\u2014 shifts the focus to \u2018limitarianism\u2019, the view that there should be upper limits on the distribution of valuable goods, and will investigate the plausibility of limitarianism in the area of economic and ecological resources. We will analyse whether such a view can be justified, that is, supported by robust philosophical argumentation, and what limitarian institutions could look like. ", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["726153"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE", "INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE"], "EU_Contribution": ["EUR 1 999 025"], "Project_Title": ["Establishment and maintenance of gene expression by heterochromatin factors"], "Total_Cost": ["EUR 1 999 025"], "Country": ["France", "France"], "Project_ACR": ["METACHROM"], "Technology_Description": "Metastable epialleles are alleles that are variably expressed in genetically identical individuals. These epialleles are established during early development by epigenetic modifications in a process influenced by stress and the environment. The epiallele\u2019s state can subsequently be maintained throughout development and adult life. Studying the mechanisms underlying establishment and maintenance of chromatin states is critical to understanding how the environment can shape the epigenome and how it can impact on diseases and aging. Most mouse metastable epialleles result from a nearby insertion of an endogenous retrovirus, which induces position effect variegation. In mouse embryonic stem cells, these elements are silenced by the histone methyl-transferase SETDB1 which imparts heterochromatin features by tri-methylating histone H3 on lysine 9. In the same cells, telomeric H3K9me3 is also installed by SETDB1 but surprisingly, we found that H3K9me3 correlates with enhanced transcriptional activity at telomeres. I hypothesize here that metastable chromatin states are controlled by H3K9me3 and associated factors, which are targeted to defined positions that can either instruct silencing, or support active expression. To understand how metastable chromatin states are regulated, we will first use a locus-specific chromatin proteomics approach to identify H3K9me3-dependent factors in the contexts of transcription or repression. Next, both pathways will be reconstituted by tethering those factors at specific positions on model genes, and maintenance of these states will be analyzed. Finally, to obtain a comprehensive picture of the metastable states establishment and maintenance, we will map heterochromatin factors genome-wide, in response to distinct stimuli in mESCs. This proposal will deepen our understanding of the mechanisms by which mammals use gene regulation to adapt to environmental conditions.", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-06-01"], "Project_ID": ["724835"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["TECHNISCHE UNIVERSITEIT DELFT", "TECHNISCHE UNIVERSITEIT DELFT"], "EU_Contribution": ["EUR 149 998"], "Project_Title": ["Adaptive Imaging Microscopy"], "Total_Cost": ["EUR 149 998"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["AIM"], "Technology_Description": "The project has a goal of starting up a small business producing highly special customizable microscope systems for biomedical research. Microscopic imaging is one of the major drivers of the progress in biomedical and life sciences. The development of novel concepts, addressing the challenges of advanced optical microscopy, represents the front line of scientific research. Modern microscopes are not purely optical devices anymore. They have developed into complex integrated systems, combining optics, mechanics, electronics, feedback control systems, and image processing Many novel concepts of modern microscopy, while very interesting for research, still have to prove the commercial profitability. Such developments can be effectively addressed by start-up companies with a goal of either custom development, production and service of these advanced systems, or development and selling the IP to a larger player. ", "To": ["2018-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["737564"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 149 811"], "Project_Title": ["Implementing Special Nanomaterials in Ultra-performance Mobile Radomes"], "Total_Cost": ["EUR 149 811,25"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["OxfordNano"], "Technology_Description": "OxfordNano aims to enhance the EU manufacturing capability in aerospace composite structures using special nanomaterials (NMs) technology derived from ERC research. The target application for this capability is ultra-performance radomes for airborne sensors systems and a growing opportunity to deliver digital services to users on the move e.g. passengers in civil aircraft and trains.", "To": ["2019-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["754748"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["NATURAL ENVIRONMENT RESEARCH COUNCIL", "NATURAL ENVIRONMENT RESEARCH COUNCIL"], "EU_Contribution": ["EUR 1 999 110"], "Project_Title": ["Gauging Ocean organic Carbon fluxes using Autonomous Robotic Technologies"], "Total_Cost": ["EUR 1 999 110"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["GOCART"], "Technology_Description": "Climate change driven by CO2 emissions from human activities is a significant challenge facing mankind. An important component of Earth\u2019s carbon (C) cycle is the ocean\u2019s biological C pump; without it atmospheric CO2 would be ~50% higher than it is now. The pump consists of sinking organic matter which is remineralised back into CO2 in the deep ocean. The depth at which remineralisation occurs is the main factor affecting the amount of organic C stored in the ocean. Currently we do not understand how or why remineralisation depth varies in time, which limits our ability to make robust predictions of how the future C cycle, and hence our climate, will change into the future. This is mainly due to the challenges of measuring remineralisation depth using conventional methods\u2013 a barrier which autonomous underwater vehicles are poised to overcome by providing high frequency data over long periods. This technological innovation will revolutionise our understanding of this important planetary C flux.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["724416"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 2 225 713"], "Project_Title": ["constRaining the EffeCts of Aerosols on Precipitation"], "Total_Cost": ["EUR 2 225 713"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["RECAP"], "Technology_Description": "Precipitation is of fundamental importance so it is vital to understand its response to anthropogenic perturbations. Aerosols have been proposed to significantly affect precipitation [e.g. Ramanathan et al., 2001]. However, despite major research efforts evidence for a systematic aerosol effect on precipitation remains \u201cambiguous\u201d [IPCC AR5, Stocker et al., 2013].", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["724602"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 255 697,50"], "Project_Title": ["New Directions in Derived Algebraic Geometry"], "Total_Cost": ["EUR 1 255 697,50"], "Country": ["France", "France"], "Project_ACR": ["NEDAG"], "Technology_Description": "New Directions in Derived Algebraic Geometry: In this proposal we propose to give a new impulsion on derived algebraic geometry by exploring new domains of applicability as well as developing new ideas and fundamental results. For this, we propose to focus on the, still very much unexplored, interactions of derived algebraic geometry with an extremely rich domain: singularity theory (to be understood in a broad sense, possibly in positive and mixed characteristics, but also singularities of meromorphic flat connections and of constructible sheaves). We plan to use the fruitful interactions between these two subjects in a two-fold manner: on the one hand derived techniques will be used in order to prove long standing open problems, and on the other hand we propose new developments in derived algebraic itself and thus open new research directions.The proposal has three major parts, interacting with each other in a coherent manner. In a first part we explore some direct applications of derived techniques to the study of singularities of degenerating families of proper schemes with the objective to prove a long standing major conjecture in the subject: the Bloch\u2019s conductor formula. This is achieved by the introduction of a new trend of ideas in non-commutative geometry and more precisely by the introduction of a trace formula in the non-commutative setting. The second part is devoted to the exploration of trace and index formula for sheaves in two different, but very similar, setting: l-adic constructible sheaves and quasi-coherent sheaves with flat connections along a given algebraic foliations. In a third part we propose to make progress towards an unexplored domain: moduli spaces of flat, possibly irregular, connections on higher dimensional varieties and their relations with Poisson and symplectic geometry. The objective here is a far reaching generalization of fundamental results on moduli spaces of flat connections on open curves and their symplectic aspects.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["741501"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["THE HEBREW UNIVERSITY OF JERUSALEM", "THE HEBREW UNIVERSITY OF JERUSALEM"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Speleothems paleoclimate: accounting for isotopic disequilibrium"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Israel", "Israel"], "Project_ACR": ["SPADE"], "Technology_Description": "Understanding and quantifying the impacts of climate change at the regional and hemispheric scales are particularly difficult with respect to changes in rainfall and temperature patterns that lead to extended droughts and flooding events. Isotopic records in speleothems are increasingly used to determine climate variability on land and for data-model comparisons. However, transferring speleothem records into quantitative climate parameters suffers from a major limitation: speleothem formation processes result in geochemical disequilibrium and there is currently no way to correct for it in paleoclimate data. SPADE will shift the treatment of paleoclimate archives from regarding them as recorders of slow geological processes to consideration of geological material as recording much faster chemical reactions. As such, they cannot be assumed to form at equilibrium. SPADE will create a new framework, based on one classic and two novel isotopic tracers in carbonates (\u03b418O-\u039417O-\u039447) to quantify disequilibrium in cave records and overcome this underlying limitation. SPADE\u2019s unique approach is based first on laboratory experiments that isolate chemical processes of speleothem formation, to test their respective effects on isotopic disequilibrium. Then speleothem analog experiments and modern cave material are combined to create speleothem specific calibrations for these isotopic proxies. These SPADE results will then be applied to classic paleoclimate records of dryland hydrology, such as Soreq Cave (Israel) and Devils Hole (Nevada). SPADE will address long standing climatic hypotheses regarding the interplay between temperature, amount of rainfall, surface evaporation, moisture sources, and regional climate connections in these drought vulnerable regions, and will make these records much more useful. A detailed understanding of disequilibrium will enable the use of these innovative geochemical tools in speleothems and more broadly, in other paleoclimate carbonate archives.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["724097"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["FUNDACIO CENTRE DE REGULACIO GENOMICA", "FUNDACIO CENTRE DE REGULACIO GENOMICA"], "EU_Contribution": ["EUR 1 986 178"], "Project_Title": ["Reticulate evolution: patterns and impacts of non-vertical inheritance in eukaryotic genomes."], "Total_Cost": ["EUR 1 986 178"], "Country": ["Spain", "Spain"], "Project_ACR": ["RETVOLUTION"], "Technology_Description": "The traditional view is that species and their genomes evolve only by vertical descent, leading to evolutionary histories that can be represented by bifurcating lineages. However, modern evolutionary thinking recognizes processes of reticulate evolution, such as horizontal gene transfer or hybridization, which involve total or partial merging of genetic material from two diverged species. Today it is widely recognized that such events are rampant in prokaryotes, but a relevant role in eukaryotes has only recently been acknowledged. Unprecedented genomic and phylogenetic information, and recent work from others and us have shown that reticulate evolution in eukaryotes is more common and have more complex outcomes than previously thought. However, we still have a very limited understanding of what are the impacts at the genomic and evolutionary levels. To address this, I propose to combine innovative computational and experimental approaches. The first goal is to infer patterns of reticulate evolution across the eukaryotic tree, and relate this to current biological knowledge. The second goal is to trace the genomic aftermath of inter-species hybridization at the i) long-term, by analysing available genomes in selected eukaryotic taxa, ii) mid-term, by sequencing lineages of natural fungal hybrids, and iii) short-term, by using re-sequencing and experimental evolution in yeast. A particular focus is placed on elucidating the role of hybridization in the origin of whole genome duplications, and in facilitating the spread of horizontally transferred genes. Finally results from this and other projects will be integrated into emerging theoretical frameworks. Outcomes of this project will profoundly improve our understanding of reticular processes as drivers of eukaryotic genome evolution, and will impact other key aspects of evolutionary theory, ranging from the concept of orthology to the eukaryotic tree of life.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["724173"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 947 208"], "Project_Title": ["Boosting tryptophan fluorescence with optical nanoantennas to watch label-free protein dynamics with single molecule resolution at high concentration"], "Total_Cost": ["EUR 1 947 208,13"], "Country": ["France", "France"], "Project_ACR": ["TryptoBoost"], "Technology_Description": "Proteins execute a broad range of functions that are central to life. Understanding these functions ultimately requires experiments at the single protein level to reveal dynamics and heterogeneities hidden in ensemble-averaged measurements. Currently, the preferred method to study single protein machineries is based on fluorescence techniques. However, fluorescence experiments suffer from major challenges: the need for external fluorescent labeling, weak signals and low non-physiological concentrations in the nanomolar range. These challenges severely limit the applicability and biological relevance of single molecule fluorescence on proteins. The TryptoBoost project aims to overcome all the previous challenges, and efficiently monitor single label-free proteins using their intrinsic tryptophan fluorescence enhanced by optical nanoantennas in the ultraviolet. Using the natural amino acid fluorescence rules out all drawbacks due to external labeling, while the optical nanoantennas enable single protein analysis at the physiologically relevant micromolar concentrations thanks to the localization and enhancement of light-matter interactions at the nanoscale. To demonstrate the power of this new technology, our interdisciplinary team will probe the important biological problems of amyloid aggregation and tumor suppressor p53 protein folding dynamics at high concentrations. The TryptoBoost approach is directly applicable to any protein containing aromatic amino acids. This condition is met by more than 90% of human proteins, so the project breakthroughs will benefit a broad range of biophysical, chemical, and medical applications. For instance, it will improve the development of therapeutic drugs, increase the detection sensitivity and read-out speed in analytical biosensing on chip, and provide new nanostructures to enhance ultraviolet photocatalysis.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-10-01"], "Project_ID": ["723241"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["HELMHOLTZ-ZENTRUM FUER INFEKTIONSFORSCHUNG GMBH", "HELMHOLTZ-ZENTRUM FUER INFEKTIONSFORSCHUNG GMBH"], "EU_Contribution": ["EUR 1 998 750"], "Project_Title": ["Clearance Of Microbial Biofilms by Advancing diagnostics and Therapy"], "Total_Cost": ["EUR 1 998 750"], "Country": ["Germany", "Germany"], "Project_ACR": ["COMBAT"], "Technology_Description": "Every year chronic infections in patients due to biofilm formation of pathogenic bacteria are a multi-billion Euro burden to national healthcare systems. Despite improvements in technology and medical services, morbidity and mortality due to chronic infections have remained unchanged over the past decades. The emergence of a chronic infection disease burden calls for the development of modern diagnostics for biofilm resistance profiling and new therapeutic strategies to eradicate biofilm-associated infections. However, many unsuccessful attempts to address this need teach us that alternative perspectives are needed to meet the challenges.", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-05-01"], "Project_ID": ["724290"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["THE UNIVERSITY OF EDINBURGH", "THE UNIVERSITY OF EDINBURGH"], "EU_Contribution": ["EUR 1 996 792"], "Project_Title": ["Form-Independent Semantics for Natural Language Understanding"], "Total_Cost": ["EUR 1 996 792"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["SEMANTAX"], "Technology_Description": "The project addresses the most important open problem in NLP, to develop a robust semantics that is invariant across different linguistic forms within a language and across languages, and embodies aspects of common-sense knowledge. It will be derived by machine-learning from machine-reading of vast amounts of text, using an existing state-of-the-art wide-coverage CCG semantic parser developed under previous ERC funding to the PI, initially to build traditional semantic analyses of sentences relating named entities.", "To": ["2022-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["742137"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["WEIZMANN INSTITUTE OF SCIENCE", "WEIZMANN INSTITUTE OF SCIENCE"], "EU_Contribution": ["EUR 2 484 722"], "Project_Title": ["Single-molecule spectroscopy of coordinated motions in allosteric proteins"], "Total_Cost": ["EUR 2 484 722"], "Country": ["Israel", "Israel"], "Project_ACR": ["SMALLOSTERY"], "Technology_Description": "Critical for the function of many proteins, allosteric communication involves transmission of the effect of binding at one site of a protein to another through conformational changes. Yet the structural and dynamic basis for allostery remains poorly understood. In particular, there is no method to follow coordinated large-scale motions of domains and subunits in proteins as they occur. Since the subunits of allosteric proteins often contain multiple domains, any such method entails probing the dynamics along several intra-protein distances simultaneously.", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["742637"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSIDADE DO MINHO", "UNIVERSIDADE DO MINHO"], "EU_Contribution": ["EUR 1 998 938,92"], "Project_Title": ["Cells-self Extracellular Matrices-based Bioinks to create accurate 3D diseased skin tissue models"], "Total_Cost": ["EUR 1 998 938,92"], "Country": ["Portugal", "Portugal"], "Project_ACR": ["ECM_INK"], "Technology_Description": "It has been recognized that growing cells within 3D structures reduces the gap between 2D in vitro cell cultures and native tissue physiology. This has been paving the way for the development of reliable 3D in vitro cell-based platforms with major impact in the reduction/elimination of animal experimentation, diseases modelling and drug development. So far, the many strategies that have been followed to bioengineer in vitro 3D human tissue models mostly rely on the random culture of cells within a 3D structure without reflecting the compositional and structural complexity of the native tissues. Recently proposed bioprinting technologies that allow accurate and high speed deposition of various cells and matrices at high resolution, have therefore great potential in the development of physiologically reliable 3D in vitro tissue models by recreating the different microenvironments/microfunctionalities found in each tissue. Nonetheless, among the components required for bioprinting, bioinks in particular have demanding requirements and much has still to be done regarding their intrinsic formulation to lead cell behaviour and support specific functionalities.", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Portugal"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["726061"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 212 194,80"], "Project_Title": ["Future bio-pesticides for EU: unlocking the code of Saponin Structure-Activity Relationships for use in pest management"], "Total_Cost": ["EUR 212 194,80"], "Country": ["Denmark"], "Project_ACR": ["SSAR"], "Technology_Description": "Insect pests are very damaging to worldwide food production, and there is a great demand for new environmentally-friendly bio-pesticides. Saponins are a structurally diverse class of naturally occurring plant defense compounds that are a promising resource for novel and more sustainable pesticides. Due to their detergent-like properties, saponins can disrupt the cell membranes of herbivory pests, cause cell death, and ultimately kill them. Despite the promising potential of saponins as bio-pesticides, little is yet known about which saponin chemical structures are toxic to which specific pest. The SSAR project aims to elucidate the relationship between saponin chemical structures and their biological activities and evolution. First, the genes involved in the biosynthetic pathway of saponins will be identified. Then desired or novel saponins will be produced in plant tissues through metabolic engineering with the identified genes. Finally, purified saponins will be used in bioassays with a range of pest species, to unlock the code of exactly which saponin chemical structures have a given specific biological activity. The new knowledge gained will have great industrial application potential as a generic platform for the production of bioactive compounds from plants and their use for bio-pesticides as an alternative to chemically produced pesticides. The new bio-pesticides will both help to meet society\u2019s need for more sustainable food production and to contribute to the development of the knowledge based bio-economy. Identification of genes involved in saponin biosynthetic pathway will also open the possibility to engineer and breed crop with tailored saponin-based pest resistance capabilities. The SSAR will allow me to develop as an independent and mature researcher, and extend my expertise in both academic and non-academic sectors through the training in the host institution and the collaboration with a bio-pesticide and generic agrochemicals innovative company.", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["655559"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["LE STUDIUM, AGENCE REGIONALE DE RECHERCHE ET D'ACCEUIL INTERNATIONAL DE CHERCHEURS ASSOCIES"], "EU_Contribution": ["EUR 1 699 200"], "Project_Title": ["SMART LOIRE VALLEY: Curiosity, Imagination and Intuition"], "Total_Cost": ["EUR 3 398 400"], "Country": ["France"], "Project_ACR": ["SMART LOIRE VALLEY"], "Technology_Description": "The region Centre-Val de Loire, located 130 km south of Paris, has a population of 2,5 million in an area of 40000 km\u00b2. LE STUDIUM\u00ae Loire Valley Institute for Advanced Studies has its headquarters in Orleans, the capital. LE STUDIUM\u00ae\u2019s mission is to build the human capital for research, development and innovation in region Centre, by attracting senior foreign researchers. The SMART LOIRE VALLEY (SLV) fellowship programme is designed to enhance this regional mission and support the regional implementation of the EU smart specialization concept. Over time it has demonstrated the benefits of outward looking research communities who adhere to the research values of LE STUDIUM\u00ae: Curiosity, Imagination and Intuition.", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2014-FP - Marie Sk\u0142odowska-Curie Co-funding of regional, national and international programmes (COFUND-FP)"], "Funding_scheme": ["MSCA-COFUND-FP - Fellowship programmes"], "Coordinated_in": ["France"], "Activity": ["Other"], "From": ["2015-11-01"], "Project_ID": ["665790"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2014"]}, -{"Partners": ["WEIZMANN INSTITUTE OF SCIENCE", "WEIZMANN INSTITUTE OF SCIENCE"], "EU_Contribution": ["EUR 2 461 111"], "Project_Title": ["Celestial fireworks: revealing the physics of the time-variable sky"], "Total_Cost": ["EUR 2 461 111"], "Country": ["Israel", "Israel"], "Project_ACR": ["Fireworks"], "Technology_Description": "Experimental time-domain astrophysics is on the verge of a new era as technological, computational, and operational progress combine to revolutionise the manner in which we study the time-variable sky. This proposal consolidates previous breakthrough work on wide-field surveys into a coherent program to advance our study of the variable sky on ever decreasing time-scales: from days, through hours, to minutes. We will watch how stars explode in real time in order to study the complex physics of stellar death, build new tools to handle and analyse the uniquely new data sets we are collecting, and shed light on some of the most fundamental questions in modern astrophysics: from the origin of the elements, via the explosions mechanism of supernova explosions, to the feedback processes that drive star formation and galaxy evolution.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["725161"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["EUROPEAN SOCIAL SURVEY EUROPEAN RESEARCH INFRASTRUCTURE CONSORTIUM"], "EU_Contribution": ["EUR 2 367 888"], "Project_Title": ["European Social Survey Sustainability"], "Total_Cost": ["EUR 2 367 888"], "Country": ["United Kingdom"], "Project_ACR": ["ESS-SUSTAIN"], "Technology_Description": "The societal challenges affecting European societies require responsive socio-economic policy solutions. The European Social Survey is an unparalleled resource enabling stability and change in Europeans\u2019 social attitudes to be charted. Its value for science and public policy has been recognised. However, despite such recognition and the clear success and impact of the European Social Survey research infrastructure, culminating in the award of ERIC status in 2013, there remain significant challenges to ensuring its long-term sustainability. ESS-SUSTAIN represents a comprehensive response to the different challenges and it will be instrumental in securing the sustainable future of ESS ERIC. A key challenge is ensuring the appropriate number of European countries are included, representing the different areas of geographic Europe. This is a critical requirement for meaningful analyses beyond the national level, as well as for the financial viability of the infrastructure. The most important activities in this proposal are therefore those which aim (i) to enhance the long-term commitment of existing Members and Observers of ESS ERIC, (2) effect the transfer of the current guest status of some countries to more stable memberships and (3) expand the coverage of the ESS to countries not yet affiliated. Based upon the current number of just over twenty countries participating in the ESS ERIC, a further increase of its membership will translate into lower costs of participation for all, whilst also strengthening the analytical power of its datasets.", "To": ["2018-03-31, ongoing project |"], "Meta": [""], "Topic_s": ["INFRADEV-3-2015 - Individual implementation and operation of ESFRI projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations"], "From": ["2015-10-01"], "Project_ID": ["676166"], "Call_for_Proposal": ["H2020-INFRADEV-1-2015-1"]}, -{"Partners": ["KING'S COLLEGE LONDON"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Role of Cdc42 in cancer cell adhesion to endothelial cells and platelets"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["Cdc42Adhere"], "Technology_Description": "Metastasis accounts for 90% of cancer deaths, and it is therefore important and timely to identify new therapeutic targets aimed specifically at metastasis. Cdc42 has recently been implicated in a key step of the metastatic cascade: the extravasation of circulating tumour cells, also termed transendothelial migration (TEM) . This project aims to study how Cdc42 contributes to breast cancer cell TEM in vitro and in vivo. Cdc42 regulates \u03b21\u2010integrin expression via the transcription factor serum response factor (SRF) and thereby stimulates cancer cell adhesion to endothelial cells (ECs) and TEM. To analyse the molecular basis for this regulation, downstream targets of Cdc42 will be depleted by RNAi in a panel of breast cancer cells to determine which target/s are responsible for altering \u03b21\u2010integrin expression, adhesion to ECs or TEM.", "To": ["2017-05-10, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-05-11"], "Project_ID": ["655817"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSIDADE DE AVEIRO", "GLOBAZ, S.A."], "EU_Contribution": ["EUR 154 125"], "Project_Title": ["Science@Aveiro, General public and researchers \u2013 Closing the Gap."], "Total_Cost": ["EUR 154 125"], "Country": ["Portugal", "Portugal"], "Project_ACR": ["Science at Aveiro"], "Technology_Description": "It\u2019s our intention to organize the 9th and 10th edition of the Researchers\u2019 Night initiative \u2013 The Science@Aveiro, General public and researchers \u2013 Closing the Gap. We propose two events for 2014 and 2015, around the themes of \u201cMaterials\u201d and \u201cLight\u201d respectively. Besides the different themes, this integrated edition will not forget the fact that in 2015 the Researchers Nigth\u2019 initiative will celebrate their 10th anniversary. To celebrate that, in 2014 we will launch the \u201cCompetition 10th anniversary of Researchers\u2019 Night\u201d, involving categories on drawing, photography and video. This competition is on the theme \u201cResearch is everywhere\u201d and it is dedicated to the general public but we expect more in impact at the students\u2019 community.", "To": ["2015-12-31, closed project |"], "Meta": [""], "Topic_s": ["MSCA-NIGHT-2014 - European Researchers' Night (NIGHT)"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Portugal"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2014-06-01"], "Project_ID": ["633219"], "Call_for_Proposal": ["H2020-MSCA-NIGHT-2014"]}, -{"Partners": ["COURTAULD INSTITUTE OF ART"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Worldly Matter: The Materials of Conceptual Art"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["WorldlyMatter"], "Technology_Description": "The aim of this project is to re-evaluate established narratives of Conceptual Art in North America and Western Europe and their global context. It will examine the importance of materiality and subject matter \u2013 or \u201cworldly matters\u201d, to borrow Conceptual artist Douglas Huebler\u2019s term \u2013 for Conceptual Art in the 1960s and early 1970s. Engaging with theories of conservation as well as the most recent discourses around materiality, the project combines a genuinely art historical objective, oriented towards the reconstruction of historical contexts, with broader theoretical perspectives. By studying artistic practices in-depth and reconstructing historical debates, it will make an important contribution to the history of Conceptual Art, and hence the immediate prehistory and preconditions of today\u2019s cultural production.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Other"], "From": ["2017-10-01"], "Project_ID": ["753815"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["STATENS MUSEUM FOR KUNST"], "EU_Contribution": ["EUR 200 194,80"], "Project_Title": ["Netherlandish Paintings in Ledreborg Palace: A Multi-Disciplinary Research of circa 600 Paintings"], "Total_Cost": ["EUR 200 194,80"], "Country": ["Denmark"], "Project_ACR": ["NePLeP"], "Technology_Description": "More than 600 Netherlandish seventeenth century paintings decorate the walls of Ledreborg Palace (Lejre, Denmark). The painting collection, of which a large share presumably was brought together in the first half of the eighteenth-century, consists mostly of mass-produced paintings, a novel commodity of the seventeenth century. Fascinatingly, Ledreborg Palace is not the only collection in Denmark which displays a strong emphasis on Netherlandish paintings: at least 2 other (also not disclosed) collections are known. However, the question why the Danish seem to have had a strong interest in Netherlandish paintings remains unanswered. ", "To": ["2019-04-24, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-SE - Society and Enterprise panel"], "Coordinated_in": ["Denmark"], "Activity": ["Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2017-04-25"], "Project_ID": ["753496"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA"], "EU_Contribution": ["EUR 180 277,20"], "Project_Title": ["Development of Fast Timing tools for Event Reconstruction at the high luminosity frontier"], "Total_Cost": ["EUR 180 277,20"], "Country": ["Italy"], "Project_ACR": ["FasTER"], "Technology_Description": "High luminosities at future particles colliders, such as the High Luminosity Large Hadron Collider (HL-LHC), will come at the price of a dramatic increase in the number of concurrent interactions of beam particles (referred to as pileup) per crossing in the experiments, implying serious challenges to the reconstruction of events. Due to the spread of the proton bunches along the beamline, collisions vertices at the HL-LHC are spread out over about 5 cm along the beam direction and about 160 ps in time. At the vertex densities foreseen at the HL-LHC, some vertices and the associated particles are so close to be merged by the track reconstruction forming fake jets of high transverse momentum. Moreover, the random overlap of energy deposits from neutral particles (mainly photons), that cannot be tied via a track to any vertex, will deteriorate the calorimeter performance in terms of energy measurement and particle identification, as particles appear to be less isolated. A promising tool advocated to mitigate the effects of pileup consists in complementing the high transverse (spatial) granularity of the detectors with extreme time resolution (of the order of 10 ps), that would allow energy deposits coming from different interaction vertices to be resolved in time.", "To": ["2018-04-30, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["707080"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["SWANSEA UNIVERSITY", "UNIVERSIDAD DE OVIEDO", "UNIVERSITA DEGLI STUDI DI FIRENZE", "FUNDACION AZTI - AZTI FUNDAZIOA", "NATURAL RESOURCES BODY FOR WALES", "NEMO Nature and Environment Management Operators S.r.l", "NEOALGAE MICRO SEAWEEDS PRODUCTS SL"], "EU_Contribution": ["EUR 2 079 605,16"], "Project_Title": ["AQUAtic INVAders: Early Detection, Control and Management"], "Total_Cost": ["EUR 2 079 605,16"], "Country": ["United Kingdom", "Spain", "Italy", "Spain", "United Kingdom", "Italy", "Spain"], "Project_ACR": ["AQUAINVAD-ED"], "Technology_Description": "Aquatic Invasive Species (AIS) are on the rise due to the synergistic effects of climate change and habitat destruction. The impacts of AIS on Biodiversity, human health, and loss of ecosystem services are well known, but their control and management has now become a worldwide priority. Successful management of AIS is challenging because it requires several steps in succession: (1) early detection, (2) identification of routes of introduction and pathways of dispersal, and (3) development of efficient control measures. However, public awareness and stakeholder involvement are also critical .The main research goal of AQUAINVAD-ED is to exploit novel molecular advances combined with the power of citizen science to develop innovative methods of early detection, control and management of AIS. This will be achieved via a multi-disciplinary network of experts in invasion biology, aquatic biotechnology, citizen science and environmental policy working from 3 different countries. The inter-sectoral dimension of the consortium consists of fundamental and applied scientists from 3 universities, 1 technological institute, 2 government agencies, 1 NGO and 5 SMEs. AQUAINVAD-ED will catalyse research and commercial activity in the detection and management of AIS, as well as in the implementation of codes of good practice for the European industry and Government agencies. This will be achieved by training the next generation of researchers on the principles of invasion biology, providing them with the skills necessary to detect and quantify the ecological and socio-economic impacts of AIS and the ability to communicate science to the general public. The training program will be delivered through individual research projects, active participation in network activities and a unique combination of specialised courses, designed to increase employability in the consultancy sector, government, academia, and the water industry.", "To": ["2019-05-31, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-06-01"], "Project_ID": ["642197"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["ISTANBUL TEKNIK UNIVERSITESI"], "EU_Contribution": ["EUR 145 845,60"], "Project_Title": ["Fate and Toxic Effects of Silver Nanoparticles and Its Transformation Products in Soil Applied with Biosolids"], "Total_Cost": ["EUR 145 845,60"], "Country": ["Turkey"], "Project_ACR": ["TESNinSAB"], "Technology_Description": "Sewage sludge management is one of the most challenging waste issues in Environmental Engineering field due to their highly polluted nature and high volume. On the other hand, sewage sludge, which is also called as biosolids, can be a nutrient resource for the agri-foods which leads to their usage in agriculture as fertilizers. Usage of biosolids as fertilizer is the most desirable management strategy since it provides resource recovery and prevents the usage of synthetic chemicals which can be harmful for human and environment health. Therefore, after the treatment of biosolids to meet the required quality criteria, their ultimate disposal as fertilizer has to be sustained. Up to date, organic, metallic or hazardous pollutants were addressed to be removed from biosolids before land spreading and standards were defined in regulations. However, there are new concerning pollutants for biosolids application to agricultural lands. One of the most recent and biggest concerns is the presence of silver nanoparticles (AgNPs), which are widely used as biocides in the consumer products and are shown to occur in wastewater treatment plants, mostly, in biosolids. They are, as a source of ionic and nano Ag, among the emerging pollutants which are known to have potential to pose threat to human and environment health and have not been included in monitoring lists, yet. Therefore, the aim of this research is to advance the state of the art in land spread of biosolids through the investigation of the toxic effects and bioacculumation of AgNPs and its transformation products in soil organisms. For excellence in research, the knowledge about the toxic effects is integrated with environmental risk assessment which will enable necessary actions such as proposing guidelines for biosolids applications.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Turkey"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["704803"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITE GRENOBLE ALPES"], "EU_Contribution": ["EUR 1 962 000"], "Project_Title": ["Grenoble Quantum Engineering Doctoral Programme"], "Total_Cost": ["EUR 3 924 000"], "Country": ["France"], "Project_ACR": ["GreQuE"], "Technology_Description": "Quantum engineering is a novel domain of research, built on fundamental research carried out in the last 20 years all over the world. Quantum technologies offer radically new materials and devices for the next century, in sectors such as security, energy, communications, or healthcare. To transform such disruptive scientific concepts into real life benefits it is crucial to develop research aiming at higher technology readiness levels. To ensure that Europe takes the leadership in this coming quantum revolution, we must train next generation quantum engineers, by offering doctoral training in interconnected domains with the highest scientific standards, while equally providing an opening to the industrial world.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2016 - Co-funding of regional, national and international programmes"], "Funding_scheme": ["MSCA-COFUND-DP - Doctoral programmes"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["754303"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2016"]}, -{"Partners": ["UNIVERSITAT POLITECNICA DE CATALUNYA", "SWANSEA UNIVERSITY", "ECOLE CENTRALE DE NANTES", "VOLKSWAGEN AG", "SIEMENS PLC", "AIRBUS SAS", "AIRBUS GROUP SAS", "ESI GROUP"], "EU_Contribution": ["EUR 2 080 164,96"], "Project_Title": ["Empowered decision-making in simulation-based engineering: Advanced Model Reduction for real-time, inverse and optimization in industrial problems"], "Total_Cost": ["EUR 2 080 164,96"], "Country": ["Spain", "United Kingdom", "France", "Germany", "United Kingdom", "France", "France", "France"], "Project_ACR": ["AdMoRe"], "Technology_Description": "\u201cAdMoRe: Empowered decision-making in simulation-based engineering: Advanced Model Reduction for real-time, inverse and optimization in industrial problems\u201d aims at providing in-depth training of Early Stage Researches (ESRs) in the development and application of state-of-the-art computational models and numerical methods to solve cutting-edge engineering problems. The main driving factors of all the beneficiaries are reduced order modeling techniques for real-time, inverse and optimization problems. In fact, these issues are seen by industry as a major asset to increase performance and competitiveness. The ultimate goal is to produce the next generation of European research engineers, leaders in the use of these methodologies for industry related problems.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-10-01"], "Project_ID": ["675919"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["UNIVERSITEIT LEIDEN", "UNIVERSITEIT LEIDEN"], "EU_Contribution": ["EUR 1 975 200"], "Project_Title": ["Set in Stone - A retrospective impact assessment of human and environmental resource usage in Late Bronze Age Mycenaean Monumental Architecture, Greece"], "Total_Cost": ["EUR 1 975 200"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["SETinSTONE"], "Technology_Description": "Greek Mycenaean monumental architecture has been well-studied. However, the extent to which large-scale building programmes contributed to the socioeconomic and political changes and crises that took place in Late Bronze Age Greece (c.1600-1100/1070 BC) has not been studied. The project aims to investigate human and natural resources which interacted in the Argive Plain and Attica. There, elites mobilized these resources to implement their monumental building programmes. It seeks to reveal how and why these constructions were accomplished, and what impact such large-scale prolonged building programmes had on the population over time. Methodologically, practical building processes and inherent social practices are captured via the cha\u00eene op\u00e9ratoire approach. Economic data are assessed via architectural energetics, an econometric modelling procedure translating buildings into cost-estimates including time-units of labour invested. These two approaches are triangulated with critically reviewed data sets revealing the changing broader demographic situation of the region. The latter data are extracted from published settlement and land use surveys, as well as archaeobotanical, geomorphological, climatic and mortuary studies from the Argolid. Published historical archives and the Linear B tablets provide further comparative data on regional pre-industrial land use and human activities. ", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["646667"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["SWANSEA UNIVERSITY"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["POLICY INNOVATION AND LEGITIMACY IN REGIONAL MULTI-LEVEL GOVERNANCE"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["MLGPIL"], "Technology_Description": "Multi-level policy-making between EU, national and sub-national levels has become increasingly complex. This has created the need for innovative governance solutions to address this complexity, which in turn has had an effect on political legitimacy. This project aims to address this topic by developing the linkages between procedural innovation in governance and the legitimacy of these processes in a multi-level political context, looking at how (or whether) political legitimacy can travel between governmental levels. The main research questions that will be addressed are:", "To": ["2017-09-06, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-07"], "Project_ID": ["661479"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["ISTANBUL TEKNIK UNIVERSITESI", "UNIVERSITA DEGLI STUDI DI MILANO", "IROC TECHNOLOGIES SA", "KARLSRUHER INSTITUT FUER TECHNOLOGIE", "INSTITUT POLYTECHNIQUE DE GRENOBLE"], "EU_Contribution": ["EUR 643 500"], "Project_Title": ["Synthesis and Performance Optimization of a Switching Nano-crossbar Computer"], "Total_Cost": ["EUR 724 500"], "Country": ["Turkey", "Italy", "France", "Germany", "France"], "Project_ACR": ["NANOxCOMP"], "Technology_Description": "The main goal of this project is developing a complete synthesis and optimization methodology for switching nano-crossbar arrays that leads to the design and construction of an emerging nanocomputer. New computing models for diode, FET, and four-terminal switch based nanoarrays are developed. The proposed methodology implements both arithmetic and memory elements, necessitated by achieving a computer, by considering performance parameters such as area, delay, power dissipation, and reliability. With combination of arithmetic and memory elements a synchronous state machine (SSM), representation of a computer, is realized. The proposed methodology targets variety of emerging technologies including nanowire/nanotube crossbar arrays, magnetic switch-based structures, and crossbar memories. The results of this project will be a foundation of nano-crossbar based circuit design techniques and greatly contribute to the construction of emerging computers beyond CMOS. ", "To": ["2019-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Turkey"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-12-01"], "Project_ID": ["691178"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN", "UNIVERSITY OF ULSTER", "SYDDANSK UNIVERSITET", "SPIRITAN ASYLUM SERVICES INITIATIVE LIMITED", "THE DUBLIN RAPE CRISIS CENTRE LIMITED", "Police Service of Northern Ireland", "PROBATION BOARD OF NORTHERN IRELAND", "ODENSE KOMMUNE", "DANSK RODE KORS (DANISH RED CROSS)"], "EU_Contribution": ["EUR 3 316 177,44"], "Project_Title": ["COllaborative Network for Training and EXpertise in psychoTraumatology"], "Total_Cost": ["EUR 3 316 177,44"], "Country": ["Ireland", "United Kingdom", "Denmark", "Ireland", "Ireland", "United Kingdom", "United Kingdom", "Denmark", "Denmark"], "Project_ACR": ["CONTEXT"], "Technology_Description": "Mental health disorders afflict more than one-third of the EU\u2019s population each year with an annual economic cost to the EU of \u20ac432 billion. The \u2018COllaborative Network for Training and EXcellence in psychoTraumatology\u2019 (CONTEXT) is an international, interdisciplinary European Industrial Doctorate (EID) designed to address deficiencies in psychotraumatology training and innovation. A key feature of CONTEXT is the minimum 50% secondment of each ESR to the non-academic sector. Consistent with the requirements of an EID, this component grants ESRs access to populations not otherwise accessible in standard doctoral training programmes. This design will facilitate a new cohort of researchers and practitioners who can translate research into practice, thereby mitigating the impact of psychotrauma in the EU. The goal of CONTEXT is to develop a high quality, innovative research training programme to build capacity and expertise, and foster innovative practice and social enterprise in the area of psychotraumatology. The nine beneficiaries of CONTEXT represent a diverse, interconnected, intersectoral consortium, well placed to collaboratively train and supervise the 12 ESRs. Three interconnected research work packages, each targeting a priority population in Europe (EU-based asylum seekers and refugees, WP3; emergency-service personnel and humanitarian first-responders, WP4; and victims and perpetrators of childhood- and gender-based violence, WP5), address current and emergent skill and professional deficiencies that are essential in curbing the adverse social consequences of trauma-related psychological distress within the EU. CONTEXT enjoys significant support and commitment from highly regarded, international stakeholders and influencers at the political, scientific, and professional level.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other", "Other", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Other"], "From": ["2016-09-01"], "Project_ID": ["722523"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["UNIVERSITE LYON 1 CLAUDE BERNARD"], "EU_Contribution": ["EUR 232 160,40"], "Project_Title": ["Mechanistic studies of long chain omega-3 fatty acid supplementation and inflammation in metabolic syndrome."], "Total_Cost": ["EUR 232 160,40"], "Country": ["France"], "Project_ACR": ["PIMS"], "Technology_Description": "Subclinical inflammation is a key factor in the development of cardiovascular diseases. Obesity and metabolic syndrome (MetS), both diet and lifestyle-related, are highly prevalent causes of subclinical inflammation. A growing body of literature suggests that dietary long chain omega-3 polyunsaturated fatty acids (LCn-3PUFA) may attenuate MetS-associated pro-inflammatory state. However, it remains unclear whether the different LCn-3PUFA, primarily docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), have similar effects on pro-inflammatory processes because most previous studies used them in mixture. Whether efficacy of LCn-3PUFA is influenced by sex/gender is also unknown. ", "To": ["2020-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["705913"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["JOHNSON MATTHEY PLC"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Directed Evolution of Enzyme for Applied Biocatalysis at Ultrahigh Throughput in Picoliter Droplets"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["TreasureDrop"], "Technology_Description": "Enzymes have established as a new class of catalysts in the field of modern synthetic chemistry and continue to gain in importance. Directed evolution is currently one of the most promising approaches aiming at enzymes with desired catalytic activities and it's potentially directly correlates with the library size that can be screened. One of the most powerful approaches to overcome these limitations is arguable the recently introduced microfluidic droplet technology; this methodology not only allows to quickly screen millions of clones in a cost effective manner, but is also broadly applicable since fluorometric as well as colorimetric assays can be used. Interestingly, even though numerous publication highlight its potential, an unambiguous evidence of its ability to provide synthetically relevant biocatalysts still needs to be furnished. In addition, access to this technology is currently limited to a few academic research groups and thus, this approach requires further implementation to evolve as an easily manageable lab routine in the near future. ", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-SE - Society and Enterprise panel"], "Coordinated_in": ["United Kingdom"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-05-01"], "Project_ID": ["752435"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 2 246 536"], "Project_Title": ["Criticality and Dual Superfluidity"], "Total_Cost": ["EUR 2 246 536"], "Country": ["France", "France"], "Project_ACR": ["CRITISUP2"], "Technology_Description": "Low temperature matter exhibits a spectacular variety of highly ordered states that occur through phase transitions. In quantum systems, phase transitions and associated critical phenomena constitute a central issue of modern physics. Wilson\u2019s theory of renormalization showed that very different physical systems could be unified under the same universality class characterized by critical exponents. The high degree of control offered by ultracold atom experiments sets them as an ideal platform for the investigation of phase transitions and critical phenomena.", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-05-01"], "Project_ID": ["743159"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["DANMARKS TEKNISKE UNIVERSITET"], "EU_Contribution": ["EUR 212 194,80"], "Project_Title": ["Dynamic performance modelling and controller design of a mini-scale organic Rankine cycle unit for heavy duty vehicles"], "Total_Cost": ["EUR 212 194,80"], "Country": ["Denmark"], "Project_ACR": ["DYNCON-ORC"], "Technology_Description": "Internal combustion engines of heavy duty vehicles convert only approximately 40 % of the combustion heat to mechanical power, while rest of the heat is rejected into the environment as waste heat. An organic Rankine cycle unit that recovers part of this waste heat is expected to reduce the fuel consumption and carbon dioxide emissions by about 15 % of the heavy duty vehicle. However, the waste heat from internal combustion engines of heavy duty vehicles is characterized by large fluctuations in load, making it a challenging task to control an organic Rankine cycle unit in an efficient, safe and cost-effective manner. A few prototype of mini organic Rankine cycle units for truck applications have been tested, but no commercial products are available; the aforementioned control challenge being the major barrier for their commercialization. The primary objective of DYNCON-ORC is to develop an appropriate controller for a mini-scale organic Rankine cycle unit for waste heat recovery from internal combustion engines of heavy duty vehicles. Advanced numerical models of the organic Rankine cycle unit including its components will be developed for simulation of the steady state and dynamic operational conditions. Based on the results of the dynamic model, a non-linear model predictive controller will be designed and optimized. The numerical models will be experimentally validated and implemented on a real organic Rankine cycle system. Through the collaboration with international, world-leading partners from industry and academia it is ensured that the project will be successfully completed and that the findings of the project will be transferred to and implemented in industry. In broader terms, the project will contribute to the development of a more efficient energy system for vehicles, reducing the fuel consumption and carbon dioxide emissions of the transportation sector, thus helping to attain socio-economic and environmental targets in context of the EU 2020 vision.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["751947"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["DANMARKS TEKNISKE UNIVERSITET"], "EU_Contribution": ["EUR 212 194,80"], "Project_Title": ["A Biomimetic Learning Control Scheme for control of Modular Robots"], "Total_Cost": ["EUR 212 194,80"], "Country": ["Denmark"], "Project_ACR": ["BIOMODULAR"], "Technology_Description": "Motor control is a very important feature in the human brain for the performance of a motor skill. The biological basis of this feature can be better understood by emulating the cerebellar mechanisms of learning. The cerebellum plays a key role in implementing fine motor control, since it extracts the information from sensory-motor signals and uses it to respond to the environment. The purpose of this project is to benefit from the interplay between a body agent and an embodied artificial brain to understand the role of the first in the behavior of the latter and vice versa. The project aims to build a novel bio-inspired computational learning model for modular robots, and to incorporate it into a biologically plausible control scheme. The aforementioned model will merge machine learning techniques and a spiking modular cerebellum to develop a process that leads to the formation of long-term motor memories. Novel modular robots, such as Fable, will benefit from this adaptive predictive control system to perform desired, task-fulfilling behaviors. Exploiting this approach, the project pursues the discovery of important insights into the modular structure of the cerebellum, and its involvement in processing the sensory input for motor control tasks. The project will be developed at DTU with a run time of two years and will benefit from collaborations with other research groups (UGR and TUM). Their long expertise in neuromorphic computing and spiking networks will ensure that the candidate receives scientific training related to these fields (e.g. about cerebellar topology and cellular properties, and implementation of spiking networks in hardware). By providing multiple relevant contributions across the spectrum of the H2020 objectives in terms of its potential to advance robotic manufacturing, brain processing understanding, and novel computing paradigms, this project will enable the candidate to enhance her position at the forefront of advances in this fields.", "To": ["2019-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-02-01"], "Project_ID": ["705100"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["VILNIAUS UNIVERSITETAS", "VILNIAUS UNIVERSITETAS"], "EU_Contribution": ["EUR 2 499 875"], "Project_Title": ["Single-cell temporal tracking of epigenetic DNA marks"], "Total_Cost": ["EUR 2 499 875"], "Country": ["Lithuania", "Lithuania"], "Project_ACR": ["EpiTrack"], "Technology_Description": "Over the past decade, epigenetic phenomena have taken centre stage in our understanding of gene regulation, cellular differentiation and human disease. DNA methylation is a prevalent epigenetic modification in mammals, which is brought about by enzymatic transfer of methyl groups from the S-adenosylmethionine (SAM) cofactor by three known DNA methyltransferases (DNMTs). The most dramatic epigenomic reprogramming in mammalian development occurs after fertilization, whereby a global loss of DNA methylation is followed by massive reinstatement of new methylation patterns, different for each cell type. Although DNA methylation has been extensively investigated, key mechanistic aspects of these fascinating events remain obscure. The goal of this proposal is to bridge the gap in our understanding of how the genomic methylation patterns are established and how they govern cell plasticity and variability during differentiation and development. These questions could only be answered by precise determination of where and when methylation marks are deposited by the individual DNMTs, and how these methylation marks affect gene expression. To achieve this ambitious goal, we will metabolically engineer mouse cells to permit SAM analog-based chemical pulse-tagging of their methylation sites in vivo. We will then advance profiling of DNA modifications to the single cell level via innovative integration of microdroplet-based barcoding, precise genomic mapping and super-resolution imaging. Using this unique experimental system we will determine, with unprecedented detail and throughput, the dynamics and variability of DNA methylation and gene expression patterns during differentiation of mouse embryonic cells to neural and other lineages. This project will give a comprehensive, time-resolved view of the roles that the DNMTs play in mammalian development, which will open new horizons in epigenomic research and will advance our understanding of human development and disease.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Lithuania"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["742654"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 2 235 815"], "Project_Title": ["Spatiotemporal organisation of bacterial outer membrane proteins"], "Total_Cost": ["EUR 2 235 815"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["OMPorg"], "Technology_Description": "The outer membrane (OM) of Gram-negative bacteria protects against environmental insult and is central to pathogenesis hence finding ways to disrupt its integrity is a route towards new antibiotics. However, our understanding of OM biology is limited. In particular, how the OM is organised is largely unknown. My laboratory recently discovered spatiotemporal Outer Membrane Protein organisation (OMPorg) in Escherichia coli, a new organising principle that explains how OMPs are turned over. We found that OMPs cluster into islands that can be mimicked in supported bilayers using purified proteins. As cells grow, OMP islands are displaced to the poles by new islands, leading to binary partitioning of old OMPs in repository cells following septation.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["742555"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "UNIVERSIDAD DE ALCALA", "UNIVERSITAT POLITECNICA DE VALENCIA", "VRIJE UNIVERSITEIT BRUSSEL", "TEL AVIV UNIVERSITY", "LEIBNIZ-INSTITUT FUER PHOTONISCHE TECHNOLOGIEN E.V.", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "RISE ACREO AB", "FIBERCORE LIMITED", "AGENCE NATIONALE POUR LA GESTION DES DECHETS RADIOACTIFS"], "EU_Contribution": ["EUR 3 880 324,44"], "Project_Title": ["Fibre Nervous Sensing Systems"], "Total_Cost": ["EUR 3 880 324,44"], "Country": ["Switzerland", "Spain", "Spain", "Belgium", "Israel", "Germany", "United Kingdom", "Sweden", "United Kingdom", "France"], "Project_ACR": ["FINESSE"], "Technology_Description": "The unprecedented properties of optical fibres make them ideal to be implemented as 'artificial nervous systems', enabling any tool or structure to become a sensitive and smart object. Conventional optical fibres are small, low-cost and can be seamlessly integrated in materials, in engineering structures and in the environment. By exploiting the most advanced light-matter interactions, these tiny luminous wires can realize distributed sensing, which means that each point along an optical fibre can separately and selectively sense quantities such as temperature, strain, acoustic waves and pressure, in perfect similarity to a real organic nerve.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations"], "From": ["2016-10-01"], "Project_ID": ["722509"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 1 999 965"], "Project_Title": ["Nanoengineering of radioactive seeds for cancer therapy and diagnosis"], "Total_Cost": ["EUR 1 999 965"], "Country": ["Spain", "Spain"], "Project_ACR": ["NEST"], "Technology_Description": "One of the major challenges in modern society is the early diagnosis and treatment of diseases. Cancer is one of the most relevant diseases worldwide because of its incidence, prevalence and mortality. During the past decades, considerable efforts have been devoted to understand the origin of the disease, find early detection methods that could improve the survival rate of cancer patients or develop treatments and devices that could reduce or eradicate cancer. The application of nanotechnology to medicine (nanomedicine) has become one of the most promising routes for the diagnosis and treatment of diseases. The small size of nanomaterials, large surface area and high reactivity impart unique physicochemical properties to these materials, in such a way that several therapeutics based on nanomaterials (liposomes, nanoparticles, polymers) have already been approved for clinical use in humans. However, there are still limitations that need to be overcome to obtain novel and efficient nanocarriers for oncology applications.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-10-01"], "Project_ID": ["725743"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["KOZEP-EUROPAI EGYETEM", "KOZEP-EUROPAI EGYETEM"], "EU_Contribution": ["EUR 1 179 462"], "Project_Title": ["Cognitive tomography of mental representations"], "Total_Cost": ["EUR 1 179 462"], "Country": ["Hungary", "Hungary"], "Project_ACR": ["COGTOM"], "Technology_Description": "Internal models are fundamental to our understanding of how the mind constructs percepts, makes decisions, controls movements, and interacts with others. Yet, we lack principled quantitative methods to systematically estimate internal models from observable behaviour, and current approaches for discovering their mental representations remain heuristic and piecemeal. I propose to develop a set of novel 'doubly Bayesian' data analytical methods, using state-of-the-art Bayesian statistical and machine learning techniques to infer humans' internal models formalised as prior distributions in Bayesian models of cognition. This approach, cognitive tomography, takes a series of behavioural observations, each of which in itself may have very limited information content, and accumulates a detailed reconstruction of the internal model based on these observations. I also propose a set of stringent, quantifiable criteria which will be systematically applied at each step of the proposed work to rigorously assess the success of our approach. These methodological advances will allow us to track how the structured, task-general internal models that are so fundamental to humans' superior cognitive abilities, change over time as a result of decay, interference, and learning. We will apply cognitive tomography to a variety of experimental data sets, collected by our collaborators, in paradigms ranging from perceptual learning, through visual and motor structure learning, to social and concept learning. These analyses will allow us to conclusively and quantitatively test our central hypothesis that, rather than simply changing along a single 'memory strength' dimension, internal models typically change via complex and consistent patterns of transformations along multiple dimensions simultaneously. To facilitate the widespread use of our methods, we will release and support off-the-shelf usable implementations of our algorithms together with synthetic and real test data sets.", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Hungary"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["726090"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["TECHNISCHE UNIVERSITAT DORTMUND", "TECHNISCHE UNIVERSITAT DORTMUND"], "EU_Contribution": ["EUR 1 994 791"], "Project_Title": ["Coherent optical control of multi-functional nano-scale hybrid units"], "Total_Cost": ["EUR 1 994 791"], "Country": ["Germany", "Germany"], "Project_ACR": ["hyControl"], "Technology_Description": "In the physics and chemistry of materials science, an intense focus of forefront research is the search for ever-smaller and ever-faster building blocks for information and communication technology (ICT) applications. The realization of next-generation devices, in ICT fields such as spintronics, spin-orbitronics and plasmonics, will depend decisively on our ability to generate new functionalities that can be actively controlled on the shortest length and time scales.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["725767"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["TECHNISCHE UNIVERSITAT DORTMUND", "TECHNISCHE UNIVERSITAT DORTMUND"], "EU_Contribution": ["EUR 1 979 679"], "Project_Title": ["Programmable Readers, Writers, and Erasers of the Epigenetic Cytosine Code"], "Total_Cost": ["EUR 1 979 679"], "Country": ["Germany", "Germany"], "Project_ACR": ["EPICODE"], "Technology_Description": "Human DNA contains two types of biologically instructive information: the canonical nucleobases A, G, T, C, and the epigenetic nucleobases mC, hmC, fC, and caC. Canonical nucleobases encode the identity of all RNAs and proteins that are synthesized by a cell, whereas epigenetic nucleobases regulate this synthesis. This regulation shapes the phenotype of cells, and its perturbation is a key trigger of cancer.", "To": ["2022-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["723863"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["MAGYAR TUDOMANYOS AKADEMIA RENYI ALFRED MATEMATIKAI KUTATOINTEZET", "MAGYAR TUDOMANYOS AKADEMIA RENYI ALFRED MATEMATIKAI KUTATOINTEZET"], "EU_Contribution": ["EUR 1 965 340"], "Project_Title": ["Growth in Groups and Graph Isomorphism Now"], "Total_Cost": ["EUR 1 965 340"], "Country": ["Hungary", "Hungary"], "Project_ACR": ["GROGandGIN"], "Technology_Description": "\"In recent years there has been spectacular progress in studying growth in groups. A central result in this new area, obtained by Pyber-Szabo' (with a similar result proved by Breuillard-Green-Tao), shows that powers of generating subsets of finite simple groups of \"bounded dimension\" grow fast. Extending this Product Theorem Szabo' and the PI also proved a weaker version of a conjecture of Helfgott-Lindenstrauss. The Product Theorem has deep consequences in the study of groups, number theory and random walks. A central open question of the area is to remove the dependence on dimension in our Product Theorem. The PI formulated a new Conjecture, as a step forward. The way to further progress is via combining techniques from asymptotic group theory and probability theory. It is from this perspective that the current GROGandGIN proposal addresses issues concerning random walks. We examine how recent probabilistic arguments for random walks in the symmetric group may be transferred to matrix groups. While the first results in the subject of growth concern matrix groups we see an evolving theory of growth in permutation groups. This relies on earlier work of Babai and the PI which aims at finding proofs which do not use the Classification of Finite Simple Groups (CFSG). Similarly, Babai's famous Quasipolynomial Graph Isomorphism Algorithm builds on ideas from CFSG-free proofs due to him. The PI has recently removed CFSG from the analysis of Babai's algorithm. Our method goes \"halfway\" towards removing CFSG from proofs of growth results for permutation groups, currently a major open problem. The GROGandGIN initiative plans to improve various other parts of Babai's paper, working with several people who look at it from different angles, with an eye towards obtaining a Polynomial Graph Isomorphism algorithm. The GROGandGIN team will also study growth in Lie groups since the theory of random walks in Lie groups has been revitalised using analogues of our Product Theorem.\"", "To": ["2022-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Hungary"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-08-01"], "Project_ID": ["741420"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["HELSINGIN YLIOPISTO", "HELSINGIN YLIOPISTO"], "EU_Contribution": ["EUR 2 463 412"], "Project_Title": ["Quantum Fields and Probability"], "Total_Cost": ["EUR 2 463 412"], "Country": ["Finland", "Finland"], "Project_ACR": ["QFPROBA"], "Technology_Description": "Quantum Field Theory (QFT) has become a universal framework in physics to study systems with infinite number of degrees of freedom. ", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["741487"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["THE UNIVERSITY OF WARWICK"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Earthquake-resilient self-centering steel frame"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["EQRESFRAME"], "Technology_Description": "An important requirement of performance-based earthquake engineering is the simultaneous control of structural and non-structural damage. Structural damage measures are related to story drifts, inelastic deformations and residual drifts. Non-structural damage measures are related to story drifts and storey accelerations. Earthquake reconnaissance reports highlight that injuries, fatalities and economical losses related to failure of non-structural components far exceed those related to structural failures. Moreover, explicit consideration of non-structural damage becomes vital in the design of critical facilities such as hospitals carrying acceleration-sensitive medical equipment, which have to remain functional in the aftermath of an earthquake. Structural and non-structural damage results in direct and indirect losses such as repair costs and costly downtime during which the building is repaired and cannot be used or occupied. Therefore, there is an urgent need for minimal-damage structures that can truly achieve seismic resilience. ", "To": ["2017-08-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-08-31"], "Project_ID": ["654426"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["TECHNISCHE UNIVERSITEIT DELFT"], "EU_Contribution": ["EUR 6 372 000"], "Project_Title": ["LEaDing Fellows"], "Total_Cost": ["EUR 12 744 000"], "Country": ["Netherlands"], "Project_ACR": ["LEaDing Fellows"], "Technology_Description": "The LEaDing Fellow Programme offers 90 two-year postdoc positions to ambitious and excellent researchers who want to perform research in a challenging, internationally esteemed and multidisciplinary environment. The aim is to help them to develop new research skills and a view on career options in academic research or in an industrial or public setting. The programme is a joint initiative of Delft University of Technology (TU Delft), the beneficiary, and the partners Leiden University (LEI), Erasmus University Rotterdam (EUR), Erasmus University Medical Centre (Erasmus MC) and Leiden University Medical Centre (LUMC). ", "To": ["2022-01-01, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2015-FP - Marie Sk\u0142odowska-Curie Co-funding of regional, national and international programmes (COFUND-FP)"], "Funding_scheme": ["MSCA-COFUND-FP - Fellowship programmes"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-01-02"], "Project_ID": ["707404"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2015"]}, -{"Partners": ["GEANT LIMITED", "GEANT VERENIGING", "UNIVERSITAT WIEN", "UNIVERZITET U BEOGRADU", "AKADEMSKA RAZISKOVALNA MREZA SLOVENIJE", "INSTITUTE FOR INFORMATICS AND AUTOMATION PROBLEMS OF THE NATIONAL ACADEMY OF SCIENCES OF THE REPUBLIC OF ARMENIA", "UNITED INSTITUTE OF INFORMATICS PROBLEMS OF NATIONAL ACADEMY OF SCIENCES OF BELARUS", "BELNET", "BULGARIAN RESEARCH AND EDUCATION NETWORK", "HRVATSKA AKADEMSKA I ISTRAZIVACKA MREZA CARNET", "CESNET ZAJMOVE SDRUZENI PRAVNICKYCH OSOB", "\u039a\u03a5\u03a0\u03a1\u0399\u0391\u039a\u039f \u0395\u03a1\u0395\u03a5\u039d\u0397\u03a4\u0399\u039a\u039f \u039a\u0391\u0399 \u0391\u039a\u0391\u0394\u0397\u039c\u0391\u03aa\u039a\u039f \u0394\u0399\u039a\u03a4\u03a5\u039f (KYPRIAKO EREVNITIKO KAI AKADIMAIKO DIKTYO)", "VEREIN ZUR FOERDERUNG EINES DEUTSCHEN FORSCHUNGSNETZES DFN VEREIN E.V.", "FUNDACAO PARA A CIENCIA E A TECNOLOGIA", "CONSORTIUM GARR", "GEORGIAN RESEARCH AND EDUCATIONAL NETWORKING ASSOCIATION", "ETHNIKO DIKTYO EREVNAS TECHNOLOGIAS AE", "HEANET LTD", "Hariduse Infotehnoloogia Sihtasutus", "MACHBA - INTERUNIVERSITY COMPUTATION CENTER", "JISC COLLECTIONS AND JANET LIMITEDLBG", "KAUNO TECHNOLOGIJOS UNIVERSITETAS", "MACEDONIAN ACADEMIC AND RESEARCH NETWORK SKOPJE", "JAVNA USTANOVA UNIVERZITET CRNE GORE PODGORICA", "KORMANYZATI INFORMATIKAI FEJLESZTESI UGYNOKSEG", "NEMZETI INFORMACIOS INFRASTRUKTURA FEJLESZTESI IRODA", "NORDUNET A/S", "INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK", "ENTIDAD PUBLICA EMPRESARIAL RED.ES", "RESEARCH AND EDUCATIONAL NETWORKING ASSOCIATION OF MOLDOVA", "GROUPEMENT D INTERET PUBLIC POUR LERESEAU NATIONAL DE TELECOMMUNICATIONS POUR LA TECHNOLOGIE L ENSEIGNEMENT ET LA RECHERCHE", "Fondation RESTENA", "Agentia de Administrare a Retelei Nationale de Informatica Pentru Educatie si Cercetare", "ZDRUZENIE POUZIVATELOV SLOVENSKEJAKADEMICKEJ DATOVEJ SIETE-SANET", "SURFnet bv", "SWITCH", "TURKIYE BILIMSEL VE TEKNOLOJIK ARASTIRMA KURUMU", "UNIVERSITA TA MALTA", "ASSOCIATION OF USERS OF UKRAINIAN RESEARCH AND ACADEMIC NETWORK URAN", "LATVIJAS UNIVERSITATES MATEMATIKAS UN INFORMATIKAS INSTITUTS"], "EU_Contribution": ["EUR 59 000 000"], "Project_Title": ["GN4-2 Research and Education Networking - G\u00c9ANT"], "Total_Cost": ["EUR 95 904 005,75"], "Country": ["United Kingdom", "Netherlands", "Austria", "Serbia", "Slovenia", "Armenia", "Belarus", "Belgium", "Bulgaria", "Croatia", "Czech Republic", "Cyprus", "Germany", "Portugal", "Italy", "Georgia", "Greece", "Ireland", "Estonia", "Israel", "United Kingdom", "Lithuania", "Former Yugoslav Republic of Macedonia", "Montenegro", "Hungary", "Hungary", "Denmark", "Poland", "Spain", "Moldova", "France", "Luxembourg", "Romania", "Slovakia", "Netherlands", "Switzerland", "Turkey", "Malta", "Ukraine", "Latvia"], "Project_ACR": ["GN4-2"], "Technology_Description": "GN4-2 is the proposed project for the second Specific Grant Agreement under the 68-month Framework Partnership Agreement (FPA) established between the G\u00c9ANT Consortium and the European Commission in April 2015.This second phase of implementing the FPA will raise European research to the next level by promoting scientific excellence, access and re-use of research data. It will also drive European-wide cost efficiencies in scientific infrastructure by promoting interoperability with other e-infrastructures on an unprecedented scale.", "To": ["2018-12-31, ongoing project |"], "Meta": [""], "Topic_s": ["GEANT-2016 - Research and Education Networking \u2013 G\u00c9ANT"], "Funding_scheme": ["SGA-RIA - SGA-RIA"], "Coordinated_in": ["United Kingdom"], "Activity": ["Other", "Other", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Research Organisations", "Research Organisations", "Other", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Other", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Other", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Other", "Research Organisations", "Higher or Secondary Education Establishments", "Other", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Research Organisations", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations"], "From": ["2016-05-01"], "Project_ID": ["731122"], "Call_for_Proposal": ["H2020-IBA-SGA-INFRA-GEANT-2016"]}, -{"Partners": ["European Respiratory Society"], "EU_Contribution": ["EUR 1 132 800"], "Project_Title": ["REspiratory Science Promoted by International Research Exchanges 3"], "Total_Cost": ["EUR 2 265 600"], "Country": ["Switzerland"], "Project_ACR": ["RESPIRE 3"], "Technology_Description": "The European Respiratory Society (ERS) is the main scientific society in the respiratory field in Europe. ERS mission is to promote lung health and to drive globally standards for respiratory medicine. ERS aims at consistently achieving its core mission by supporting the forefront of basic and translational research. Since 1997, ERS has operated a successful programme of international exchange of researchers in respiratory science. Under the FP7 COFUND scheme, ERS launched RESPIRE 1 and RESPIRE 2 fellowship programmes. Here, ERS proposes RESPIRE 3, a new fellowship programme that capitalises on the success of the previous programmes and presents innovative features, taking into consideration the results of the independent evaluation of the RESPIRE 2 programme. First, RESPIRE 3 funds both European and global fellowships, expanding the international dimension to Third Countries. Second, RESPIRE 3 places major attention to inter-sectoral exposure: fellows have the possibility to undertake a secondment to industry, fully funded by the programme. Third, RESPIRE 3 complements the host institutions\u2019 programme by proposing training activities aimed at strengthening the professional development of the fellows. Fourth, RESPIRE 3 sets the frame for the establishment of international contacts by offering dedicated networking opportunities, namely during the annual ERS congress. Fifth, with an increased living allowance and by introducing a family allowance, RESPIRE 3 provides competitive working conditions to attract the best talents and guarantee them a right balance between career ambitions and personal development. Therefore, the proposed RESPIRE 3 programme, by training post-doctoral fellows in Europe and globally, will enhance research in the respiratory field, increase the human resources potential in Europe, and contribute to the overall objective and impact of COFUND.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2015-FP - Marie Sk\u0142odowska-Curie Co-funding of regional, national and international programmes (COFUND-FP)"], "Funding_scheme": ["MSCA-COFUND-FP - Fellowship programmes"], "Coordinated_in": ["Switzerland"], "Activity": ["Other"], "From": ["2016-09-01"], "Project_ID": ["713406"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2015"]}, -{"Partners": ["UNIVERSITY OF GLASGOW"], "EU_Contribution": ["EUR 146 591,10"], "Project_Title": ["Psychiatric spaces in transition: discourse, dwelling, doing"], "Total_Cost": ["EUR 146 591,10"], "Country": ["United Kingdom"], "Project_ACR": ["GART-PSYSPAC"], "Technology_Description": "To ask searching questions about changes in the treatment of people with mental health problems - about the extent to which they experience the right mix of 'protective' and 'empowering' support - is to probe deeply into the 'humanity' of European society. Responding to this challenge, the proposed action will combine in-depth investigation into the near-unique 'laboratory' of psychiatric transition offered by one site in Scotland, Gartnavel Royal Hospital, Glasgow, with an explicitly comparative framing derived from research on equivalent shifts occurring in Sweden. A multi-disciplinary research team, working across human geography, planning-architecture and clinical psychiatry, will deploy a range of engaged, qualitative research methods: interviewing, focus groups, walking tours, drawing work and directed photography, coupled to both standard and more experimental techniques for 'data' interpretation. Based on this research, the team will develop conceptual resources for a 'model' of European psychiatric transition, notably from institutional (asylum/hospital) to de-institutional or trans-institutional landscapes of mental health care. More empirically, the objective is to recover subjective experiences of the changing spaces of Gartnavel as felt, understood and represented by different cohorts of patients and staff (past and present), gathering these materials into a 'living archive' - available on-line and via an exhibition/event - to be made available to all connected with the site, local residents neighbouring the site and a wider public concerned with mental health matters. Through both this impact work and scholarly outputs, a further objective is critically to appraise psychiatric transition, and in particular to re-evaluate the notion of 'the asylum' in an era arguably drifting back to accepting in-patient care for categories of chronic, acute and (allegedly) 'dangerous' patients.", "To": ["2018-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["706026"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN"], "EU_Contribution": ["EUR 6 088 800"], "Project_Title": ["Cutting Edge Training - Cutting Edge Technology"], "Total_Cost": ["EUR 12 177 600"], "Country": ["Ireland"], "Project_ACR": ["EDGE"], "Technology_Description": "EDGE is a training and development programme of scientific excellence for postdoctoral researchers that offers a unique combination of disciplines and industry engagement to the 71 fellows it will recruit. Leveraging the strengths and assets of three Irish National Research Centres, AMBER, CONNECT and ADAPT, headquartered in TCD, EDGE will form the next generation of thought leaders in ICT. AMBER offers expertise in advanced materials that will play a pivotal role in future systems and devices. CONNECT\u2019s focus is on future networks that will underpin the services the world needs and ADAPT brings cutting-edge expertise in digital content. EDGE researchers will work at the interface between these Centres and will generate highly interdisciplinary projects, adding value to all. Most importantly, industry will have a primary role in defining, running and supporting the projects, and will take an active part in developing the scientists, through secondments, industry events and specialised training. ", "To": ["2021-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2015-FP - Marie Sk\u0142odowska-Curie Co-funding of regional, national and international programmes (COFUND-FP)"], "Funding_scheme": ["MSCA-COFUND-FP - Fellowship programmes"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["713567"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2015"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN"], "EU_Contribution": ["EUR 318 600"], "Project_Title": ["Trinity Long Room Hub Visiting Research Fellows COFUND programme"], "Total_Cost": ["EUR 637 200"], "Country": ["Ireland"], "Project_ACR": ["TLRH-VRF COFUND"], "Technology_Description": "The Trinity Long Room Hub Visiting Research Fellows Programme will offer opportunities to nine Experienced Researchers from across the spectrum of the Arts and Humanities to spend a fellowship of 12 months duration at Trinity Colleges\u2019 Arts and Humanities Research Institute. This fellowship programme represents a significant enhancement of the offering of the existing fellowship programme operating in the TLRH. The objectives of the programme are to attract high quality international researchers from Europe and all over the world via more attractive employment conditions including an employment contract and via wide and rigorous promotion of the calls while open. The programme will provide fellows with training and networking opportunities that will enhance their career development potential ( via their involvement in the activities of an Interdisciplinary College Research Theme affiliated to the Long Room Hub under which they will be recruited and access to a range of non research related training opportunities via different units in TCD); to identify the relevance of their work for other sectors outside academia including the public ( via the inclusion of a secondment element in the programme and via participation in the public engagement activities of the Long Room Hub) and to provide them with interdisciplinary research opportunities( again via involvement in and exposure to staff active in the Interdisciplinary Research Theme under which they have been recruited). The Interdisciplinary Research Themes involve staff across a TCD schools not only thoseaffiliated to the TLRH (i.e. Computer Science and Statistics, Engineering, Nursing, Social Work and Psychology) that will hopefully stand them in good stead as they seek to expand their academic networks. Finally Trinity College and the Long Room Hub will support the selection of researchers following an open, merit-based and impartial and equitable selection procedure, based on international peer review.", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2015-FP - Marie Sk\u0142odowska-Curie Co-funding of regional, national and international programmes (COFUND-FP)"], "Funding_scheme": ["MSCA-COFUND-FP - Fellowship programmes"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["713730"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2015"]}, -{"Partners": ["ASTON UNIVERSITY"], "EU_Contribution": ["EUR 3 186 000"], "Project_Title": ["International Mobility and Training in Photonics Programme"], "Total_Cost": ["EUR 6 372 000"], "Country": ["United Kingdom"], "Project_ACR": ["MULTIPLY"], "Technology_Description": "The aims of the proposed International Mobility and Training in Photonics programme, MULTIPLY, are to facilitate worldwide mobility and offer high-level interdisciplinary and transdisciplinary training for approximately 55 outstanding international researchers (90 fellow*years) commencing their professional development in the area of photonics science, technology and applications. Applicants from any part of the world will be able to participate in this Programme, freely choosing their destinations and research topics. Eligible researchers may apply for one of the following mobility elements: a) incoming to Europe, including Europe-to-Europe mobility; b) outgoing from Europe with re-integration.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2015-FP - Marie Sk\u0142odowska-Curie Co-funding of regional, national and international programmes (COFUND-FP)"], "Funding_scheme": ["MSCA-COFUND-FP - Fellowship programmes"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["713694"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2015"]}, -{"Partners": ["UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6", "UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6"], "EU_Contribution": ["EUR 1 455 000"], "Project_Title": ["The Evolution Problem in General Relativity"], "Total_Cost": ["EUR 1 455 000"], "Country": ["France", "France"], "Project_ACR": ["EPGR"], "Technology_Description": "General relativity has been introduced by A. Einstein in 1915. It is a major theory of modern physics and at the same time has led to fascinating mathematical problems. The present proposal focusses on two aspects of the evolution problem for the Einstein equations which has been initiated by the pioneering work of Y. Choquet-Bruhat in 1952.", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["725589"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["Enterprise Ireland"], "EU_Contribution": ["EUR 5 310 000"], "Project_Title": ["Career Development Fellowships in the National Technology Centre Programme"], "Total_Cost": ["EUR 10 620 000"], "Country": ["Ireland"], "Project_ACR": ["Career-FIT"], "Technology_Description": "Career-FIT is a new trans-national scheme that offers an opportunity for experienced researchers to develop their careers n market focused applied research in Ireland's Technology Centres. Covering a wide range of academic and industry areas aligned with Ireland's Smart Specialisation Strategy, the 15 Centres were established to encourage greater efficiency in the interaction between researchers, industry, and the public sector, in research that promotes economic growth by its direct relevance to industry agendas. Each multidisciplinary Centre offers excellent facilities and equipment for Fellow use: experienced scientific staff to support the Fellow\u2019s research, and extensive enterprise relationships on which market focused applied research can be progressed. Following two widely publicised calls that seek to attract the highest quality researchers with their own research proposals, the Career-FIT programme offers 50 fellowships of 36 months\u2019 duration for incoming mobility to the Centre Hosts, with an enterprise secondment option during the Fellowship. Selection is through a transparent process based on demonstrated excellence of the applicant, potential of the research programme, host organisation capacity to provide a developmental environment, and training/career development impact of the Fellowship. Fellows are mentored by an experienced Centre mentor(s) concerned not just for their scientific progress but also their training and development in line with agreed career goals. They will also have support from a Professional Development Advisor and will further benefit from participation in a structured development training programme that targets enhancement of personal effectiveness as well as competencies relating to innovation management. As a new programme offering interdisciplinary, intersectoral and international features, the Career-FIT human resource development objectives will guarantee the development of future research and innovation leaders.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2015-FP - Marie Sk\u0142odowska-Curie Co-funding of regional, national and international programmes (COFUND-FP)"], "Funding_scheme": ["MSCA-COFUND-FP - Fellowship programmes"], "Coordinated_in": ["Ireland"], "Activity": ["Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["713654"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2015"]}, -{"Partners": ["UNIVERSITEIT LEIDEN"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["Evolution of sexual dimorphisms: all about losing not choosing?"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["YnotSing"], "Technology_Description": "Males and females often differ dramatically in phenotype, with one sex exhibiting elaborate ornaments absent in the other. Darwin suggested such dimorphism evolves through sexual selection on males to attract females and repel rival males. Ever since, this framework served to explain why males are showy and females drab. Song in songbirds was a classic example (males sing and females are silent) until our recent research showed that female song is phylogenetically widespread and probably ancestral. Thus, current sex differences in song must have at least partly resulted from females evolving away from males by losing song. Therefore, the key question is not what has led to elaboration in males, but rather, what is responsible for losses in females. I will engage a network of experts from three EU institutions and the general public to participate in addressing this new, pertinent question of trait loss in a large-scale phylogenetic analysis across songbirds. I will focus on three goals important to progress in this field: (1) develop an urgently needed single quantitative score to compare song structure among species, (2) determine how gains and losses of song structure in each sex contribute to overall dimorphism, (3) compare dimorphism to a broad range of ecological and natural history correlates. From the host and partners, I will receive expert training through research in animal communication, bioacoustics, and character evolution, including advanced sound analysis tools during a Secondment and leadership training through a major citizen science project with xeno-canto, the world\u2019s largest bird song database. This inclusive mentorship and training will equip me with diversified and advanced skills to contribute to this important research question and embark on my career goals of leading an independent, integrated research programme in behavioural ecology and evolution.", "To": ["2018-08-31, Grant Agreement terminated |"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["703999"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["DANMARKS TEKNISKE UNIVERSITET"], "EU_Contribution": ["EUR 4 460 400"], "Project_Title": ["H.C. \u00d8rsted Fellows Programme \u2013 co-funded by Marie Sk\u0142odowska Curie Actions (COFUNDfellowsDTU)"], "Total_Cost": ["EUR 8 920 800"], "Country": ["Denmark"], "Project_ACR": ["COFUNDfellowsDTU"], "Technology_Description": "With the H.C. \u00d8rsted Fellows Programme \u2013 co-funded by Marie Sk\u0142odowska Curie Actions (COFUNDfellowsDTU) DTU will attract highly talented young researchers through incoming mobility from around the world. The Programme takes place at the Technical University of Denmark (DTU) which is a top ranked university with focus on all Engineering Sciences as well as Life Science and Biotechnology.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2015-FP - Marie Sk\u0142odowska-Curie Co-funding of regional, national and international programmes (COFUND-FP)"], "Funding_scheme": ["MSCA-COFUND-FP - Fellowship programmes"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["713683"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2015"]}, -{"Partners": ["ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE"], "EU_Contribution": ["EUR 3 398 400"], "Project_Title": ["Experienced Researchers Incoming Fellowship Programme at the Ecole Polytechnique F\u00e9d\u00e9rale de Lausanne"], "Total_Cost": ["EUR 6 796 800"], "Country": ["Switzerland"], "Project_ACR": ["EPFL Fellows"], "Technology_Description": "EPFL Fellows aims to attract experienced researchers of any nationality to EPFL - one of the leading European institutions of science and technology - to provide them with state-of-the art conditions for research in a top-class academic environment, to develop their leadership potential and to position them for success as future research leaders through an intensive training. EPFL Fellows is a relatively new programme; it started in 2013 with the support of the EU MCA-COFUND (FP7). Fellowships may be requested in any scientific discipline and run for a period of 24 months. ", "To": ["2020-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2014-FP - Marie Sk\u0142odowska-Curie Co-funding of regional, national and international programmes (COFUND-FP)"], "Funding_scheme": ["MSCA-COFUND-FP - Fellowship programmes"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-07-01"], "Project_ID": ["665667"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2014"]}, -{"Partners": ["AN TUDARAS UM ARD OIDEACHAS"], "EU_Contribution": ["EUR 4 602 000"], "Project_Title": ["Collaborative Research Fellowships for a Responsive and Innovative Europe"], "Total_Cost": ["EUR 9 204 000"], "Country": ["Ireland"], "Project_ACR": ["CAROLINE"], "Technology_Description": "The CAROLINE Fellowship Programme proposed by the Irish Research Council (IRC) will provide a unique opportunity for researchers to further develop their skills, competencies and experience through inter-sectoral collaboration with NGOs and International Organisations (IO). Proposals will be invited from all disciplines that speak to the overarching theme of global sustainable development as set out under the United Nations 2030 Agenda for shared economic prosperity, social development, and environmental protection. CAROLINE will fund 50 experienced researchers across two modes; International Fellowships (three-year) and Irish Fellowships (two-year). The IRC, a national agency, funds excellent research across all disciplines. Unique aspects of CAROLINE include the European and global resonance of the overarching research theme, the inclusion of NGO and IO partners with the host research performing organisations, flexibility in secondments, comprehensive approaches to equal opportunities and gender aspects, and dedicated core training and career support activities. Research outcomes and activities of the CAROLINE Fellows will benefit Europe, given the significance of the theme to Europe 2020, e.g. in employment, climate change and energy, education, and poverty reduction. CAROLINE will deliver experienced researchers with enhanced skills in inter-sectoral and interdisciplinary research and better access to a wider set of future career opportunities. The IRC has built an impressive array of support for this proposal from stakeholders in Ireland, Europe and internationally, including research performing-organisations, NGOs, IOs and other partners.", "To": ["2021-06-01, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2015-FP - Marie Sk\u0142odowska-Curie Co-funding of regional, national and international programmes (COFUND-FP)"], "Funding_scheme": ["MSCA-COFUND-FP - Fellowship programmes"], "Coordinated_in": ["Ireland"], "Activity": ["Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2016-06-02"], "Project_ID": ["713279"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2015"]}, -{"Partners": ["NARODOWE CENTRUM NAUKI"], "EU_Contribution": ["EUR 5 841 000"], "Project_Title": ["SUPPORTING MOBILITY IN THE ERA THROUGH AN INTERNATIONAL FELLOWSHIP PROGRAMME FOR DEVELOPEMENT OF BASIC RESEARCH IN POLAND"], "Total_Cost": ["EUR 11 682 000"], "Country": ["Poland"], "Project_ACR": ["POLONEZ"], "Technology_Description": "POLONEZ is a Fellowship Programme supporting international incoming researchers working in the broad field of research regardless of their nationality. It will be implemented by the National Science Centre (NCN), a government agency funding basic research in Poland. The NCN has already designed 11 funding schemes supporting researchers on every stage of their research career and regularly announces calls for proposals. The Centre is also involved in international funding initiatives, e.g. ERA-nets, JPIs. It follows a strictly bottom-up approach, allowing researchers to freely choose their research topic and host institution. POLONEZ, planned for 60 months, enables the NCN to implement 3 calls for proposals in order to select 90 fellows. It is targeted at experienced researchers who may apply for 12-24-month-fellowships in host institutions in Poland, both academic and non-academic, public or private. Apart from living, mobility and family allowances, they are offered a research grant which amounts to ca. \u20ac 4 200 per month, to cover the costs of a research project in a discipline freely chosen by the applicant. The fellows are also given an opportunity to participate in a variety of research and non-research trainings provided by the NCN and the host institution. One of the main goals of POLONEZ is to enhance incoming mobility in Poland. Although Polish host institutions offer an attractive research setting and high quality resources, fellowships in Poland attract fewer researchers. Also, many Polish researchers still seek temporary and permanent positions outside of Poland and Europe. Therefore, in order to counteract \u201cbrain drain,\u201d build up a positive image of Polish research institutions and encourage foreign researchers to develop their careers in Poland, we offer them the opportunity to collaborate with the best Polish research organisations. POLONEZ thus paves the way for stronger international mobility in research and the integration of research communities.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2014-FP - Marie Sk\u0142odowska-Curie Co-funding of regional, national and international programmes (COFUND-FP)"], "Funding_scheme": ["MSCA-COFUND-FP - Fellowship programmes"], "Coordinated_in": ["Poland"], "Activity": ["Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2015-09-01"], "Project_ID": ["665778"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2014"]}, -{"Partners": ["EUROPEAN MOLECULAR BIOLOGY LABORATORY"], "EU_Contribution": ["EUR 6 372 000"], "Project_Title": ["EMBL Interdisciplinary, International and Intersectorial Postdocs"], "Total_Cost": ["EUR 12 744 000"], "Country": ["Germany"], "Project_ACR": ["EI3POD"], "Technology_Description": "The EIPOD programme was developed in 2007 with the objective of making use of the excellent scientific environment available at EMBL to support an innovative fellowship programme focused on interdisciplinary research training for postdoctoral fellows. EI3POD is designed to enrich and significantly build upon the very successful EIPOD programme and bears a significant number of novel features for scientific collaboration as well as vocational skills training and career development. ", "To": ["2020-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2014-FP - Marie Sk\u0142odowska-Curie Co-funding of regional, national and international programmes (COFUND-FP)"], "Funding_scheme": ["MSCA-COFUND-FP - Fellowship programmes"], "Coordinated_in": ["Germany"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-12-01"], "Project_ID": ["664726"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2014"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Doping Colloidal Nanoplatelets: Synthesis, Self-assembly and Spectroscopy"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["DECAGON"], "Technology_Description": "Two dimensional (2D) nanomaterials have attracted rising scrutiny from the research community in the last decade due to their outstanding physical, optical and structural properties. Beyond the well-known example of graphene and other exfoliated bulk materials, a new colloidal route has recently emerged towards such materials and offers a high degree of control on the structure of these nanosheets. Among these, atomically flat, quasi-two dimensional, colloidal semiconducting (CdS, CdSe and CdTe) nanoplatelets (NPLs) have very interesting opto-electronic properties. Our goal is to fully exploit the potential of these NPLs by doping them with transition metal ions (Mn2+, Cu2+ or Ag+). With the help of doping in such small systems, we can tune the absorbance, photoluminescence, carrier density and mobility of these materials and extend the potential of these materials for various applications such as field effect transistor, light emitting devices or photovoltaic solar cells. We will devise new synthetic strategies towards doped semiconducting NPLs and characterize their structural and optical and electronic properties using state of the art techniques. Advanced structural characterization (XRD, TEM, STEM) will be coupled to optical spectroscopy (fluorescence lifetimes, absorption, emission and excitation spectra) both in solution and on single objects. Afterwards, we will assemble these thin doped platelets together to form supraparticles and large-scale assemblies using different soft-matter techniques (depletion interaction, polymer grafting, templating by an interface) in order to tune their optoelectronic properties. A fine control of the assembly process would direct to new fundamental collective effects and easy processing and orientation of doped platelets, which is a prerequisite for their use in applications.", "To": ["2018-01-10, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2016-01-11"], "Project_ID": ["661199"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITE DE STRASBOURG"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Luminescent Polymer Nanoparticles with Aza-BODIPYs, Porphyrins and their Metal Complexes for FRET Mediated Ratiometric Oxygen Sensing"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["NanoOxySens"], "Technology_Description": "This proposed Fellowship brings together an Experienced Researcher from India with expertise in the synthesis of photosensitizers and their photophysical characterization, tuning the excited-state properties, investigation of their photophysics and photobiology with an internationally recognized Host Laboratory in France with expertise in designing fluorescent molecular and nanoparticle probes for bioimaging. This project will provide (i) interdisciplinary training of highest quality to become an outstanding scientist with excellent publication record; (ii) enhance European excellence in organic synthesis, nanosciences and biophotonics. The aim of the research project is to obtain ratiometric probes for molecular oxygen based on biodegradable polymeric nanoparticles (NPs) bearing far-red/near-infrared absorbing triplet sensitizers such as aza-BODIPYs, porphyrins and corresponding metal complexes. The project involves the synthesis of phosphorescent dyes (aza-BODIPY/porphyrins) and formulation of polymeric NPs encapsulating these dyes. The development of ultra-bright polymer nanoparticles, an innovative method recently discovered in the Host Laboratory, will enable the development of novel dual emissive polymeric NPs with the triplet sensitizers. In our design, fluorescent NPs excite triplet sensitizers through energy transfer (FRET), resulting in dual emission: fluorescence of NPs and phosphoresce of the sensitizer. Only phosphorescence of FRET acceptor is sensitive to molecular oxygen (3O2), which provides the mechanism of dual colour ratiometric response to oxygen. The approach will be further validated in solutions and in living cells. The obtained nanoprobes for oxygen will be applied to living cell and (in collaboration) to whole animals. It is our strong conviction that the possibilities of this multidisciplinary chemistry are enormous, and the end result will be the development of a simple nano-device for molecular oxygen build from biodegradable materials.", "To": ["2019-05-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-15"], "Project_ID": ["705826"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Archaeology, Landscapes and Heritage in the Iberian Southeast"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["ALHIS"], "Technology_Description": "This training-through-research project at the Institute of Heritage Sciences of the Spanish National Research Council (Incipit-CSIC), aims both to generate new scientific knowledge on the archaeology of the landscapes and the socio-political processes of the Final Iron Age and the Early Roman period, and to enhance their value for cultural heritage management and development in Murcia, in the Spanish Southeast. In this sense, this proposal aims to create a fruitful link between the applicant\u2019s historical and archaeological research background and skills and the opportunities to learn and to develop a heritage outreach project. The interest of the project is due to both, the lack of landscapes studies which focus on the Iron Age in this region from a diachronical and landscape perspective, and the remarkable socio-political transformations undergone by the local communities in the period between the 5th and the 1st centuries BC. The landscape will be here understood like expression of the social and political interactions, but also like a space with an active role in their development, at different levels. All the evidences will be compiled, for the first time, through an interdisciplinary methodology (archaeological record, ancient texts, paleoenvironmental data, integration in a GIS, etc.) and will be analysed from a contextualized and comparative European perspective, which the regional research in this period lacks. Results will be disseminated by means of several impact publications but also beyond the strictly scientific environment, with the support of the host centre, the regional museums and other institutions. Regarding the heritage perspective this project aims to allow the applicant to learn how to re-direct all this knowledge towards a proper and effective management and communication of the important and rather unknown heritage value of those sites.", "To": ["2017-05-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2015-06-01"], "Project_ID": ["654906"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSIDADE DE COIMBRA"], "EU_Contribution": ["EUR 148 635,60"], "Project_Title": ["Brain stimulation of attention networks: examining old principles and developing new clinical applications"], "Total_Cost": ["EUR 148 635,60"], "Country": ["Portugal"], "Project_ACR": ["TMS_ATT"], "Technology_Description": "Attentional deficits are a frequent consequence of brain damage after stroke. Current treatment approaches using brain stimulation techniques such as transcranial magnetic stimulation (TMS) are based on two theoretical constructs, namely (1) inter-hemispheric inhibition within the dorsal attention network and (2) the presence of interactions between the ventral and dorsal attention network and. The proposed projects put these constructs to the test by combining TMS with neuroimaging and, based on these findings, explore novel brain connectivity based TMS treatments. Collectively, these projects advance current neurocognitive models of attentional control and lead to advanced TMS protocols that can alleviate attention deficits in patients.", "To": ["2018-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Portugal"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["708492"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON", "MEDICAL RESEARCH COUNCIL"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Computation of innate threats and defensive behaviour in the mouse"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["defence_SC"], "Technology_Description": "Innate defensive behaviours are emergency responses that animals use to avoid predators and environmental threats, such as escape to a safe shelter or freezing to avoid detection. Engaging in defensive behaviour at the right time and choosing the correct response is essential for survival, but little is known about how the brain achieves this. In this project we aim to understand the neural circuits that process sensory information to compute the presence of a threat and the most appropriate defensive action. We will focus on the mouse superior colliculus (SC), an evolutionarily conserved brain region thought to be crucial for defensive behaviours. ", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["706136"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSIDADE DE LISBOA", "UNIVERSIDADE DE COIMBRA", "CAMARA MUNICIPAL DE LISBOA"], "EU_Contribution": ["EUR 122 050"], "Project_Title": ["CITIZEN SCIENCE: BRIDGING THE GAP BETWEEN RESEARCH AND SOCIETY IN PORTUGAL"], "Total_Cost": ["EUR 122 050"], "Country": ["Portugal", "Portugal", "Portugal"], "Project_ACR": ["CITSCI"], "Technology_Description": "The active participation of citizens in science related issues has significantly increased in the past decades and citizen science is top-priority in many institutions and governments across Europe. Portugal, however, is still lagging a little behind. This proposal for the European Researcher\u2019s Night 2014 and 2015 in Portugal \u2013 CITSCI \u2013 has two broad aims. ", "To": ["2015-11-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-NIGHT-2014 - European Researchers' Night (NIGHT)"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Portugal"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2014-05-01"], "Project_ID": ["633379"], "Call_for_Proposal": ["H2020-MSCA-NIGHT-2014"]}, -{"Partners": ["ACADEMISCH ZIEKENHUIS GRONINGEN"], "EU_Contribution": ["EUR 1 674 240"], "Project_Title": ["Protecting patients with enhanced susceptibility to infections"], "Total_Cost": ["EUR 3 348 480"], "Country": ["Netherlands"], "Project_ACR": ["PRONKJEWAIL"], "Technology_Description": "The Microbes in Health and Disease research programme at the University Medical Center Groningen (UMCG) proposes the Doctoral Training Programme PRONKJEWAIL (\u2018a real gem\u2019) in the field of hospital care and infection. The specific training objective is \u2018protecting patients with enhanced susceptibility to infections\u2019. PRONKJEWAIL will recruit 16 international ESRs, who will be trained in research, transferable skills, and network and capacity building. They will be guided by experienced supervisors from the departments of Medical Microbiology, Internal Medicine, Intensive Care, Clinical Pharmacy and Pharmacology, Rheumatology and Immunology, Surgery, Cell Biology, and Pharmacoepidemiology and Pharmacoeconomics at the UMCG. ", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2015-DP - Marie Sk\u0142odowska-Curie Co-funding of regional, national and international programmes (COFUND-DP)"], "Funding_scheme": ["MSCA-COFUND-DP - Doctoral programmes"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["713660"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2015"]}, -{"Partners": ["RIJKSUNIVERSITEIT GRONINGEN"], "EU_Contribution": ["EUR 1 988 160"], "Project_Title": ["Local Training Network on Novel Tailor-Made Antimicrobials and Delivery Strategies From Synthesis towards Clinical Applications"], "Total_Cost": ["EUR 3 976 320"], "Country": ["Netherlands"], "Project_ACR": ["ALERT"], "Technology_Description": "The current overuse of antibiotics is leading to the emergence of multidrug resistant (MDR) bacteria. These MDR pathogens continue to evolve at a terrifying rate and confer resistance to most or all presently available antibacterial treatments. Antimicrobial resistance is an eminent global problem that calls for an integrated approach that surpasses national borders, sectors, and disciplines. The COFUND ALERT programme addresses this call by establishing a dedicated doctoral training programme with an international, interdisciplinary and inter-sectoral focus. Nineteen excellent Early Stage Researchers (ESRs) will be employed at the University of Groningen (RUG). ALERT is based at RUG but is tightly connected with multiple international academic and private partner organisations, each providing complementary research or training. ALERT aims to develop the best practices in high quality training and research. ALERT achieves this through advanced multidisciplinary research training extended with development of dedicated transferable and entrepreneurial skills. ESRs will develop novel antimicrobial drug candidates through chemical, biotechnological and nanotechnological synthesis and subsequent in vivo testing. All ALERT Principal Investigators have ample experience with supervising PhD students, which ensures an attractive and vibrant research environment for the ESRs. In addition, access to excellent modern research facilities is guaranteed. Thus, the ALERT programme creates an optimal research and training environment that is far greater than the sum of its individual parts. ALERT\u2019s long-term ambitions are to establish a strong and coherent international network that links together highly skilled young researchers as well as established scientists, who far beyond the funding period will continue to inspire each other to excel in antimicrobial resistance research in order to tackle the antimicrobial challenge.", "To": ["2021-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2015-DP - Marie Sk\u0142odowska-Curie Co-funding of regional, national and international programmes (COFUND-DP)"], "Funding_scheme": ["MSCA-COFUND-DP - Doctoral programmes"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["713482"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2015"]}, -{"Partners": ["UNIVERSITE D'AIX MARSEILLE"], "EU_Contribution": ["EUR 2 354 400"], "Project_Title": ["International, inter-sectoral and inter-disciplinary Doctoral Training Programme to Aix-Marseille University"], "Total_Cost": ["EUR 4 708 800"], "Country": ["France"], "Project_ACR": ["DOC2AMU"], "Technology_Description": "DOC2AMU raised out of the willpower of the Provence Alpes Cote d\u2019Azur key regional actors in Research and Innovation to offer to the most promising early stage researchers an international, inter-sectoral and inter-disciplinary innovative doctoral training programme. The excellence is ensured not only by the research ecosystem of Aix-Marseille University but also through the open, transparent, merit-based, impartial and equitable selection process set up to assess the perfect match between the proposed doctoral projects and the ESRs. Further to ensure the best career perspectives after ESR\u2019s\u2019 graduation, DOC2AMU set up an original training programme offering a training scheme combining options of the 3 international/inter-sectoral and interdisciplinary dimensions, including a comprehensive package of transferable skills training, along with a specific mentoring scheme involving an academic Supervisor, a non-academic and/or international tutor(s) and a Scientific & Training Supervisory Committee. Apart from the recruitment of 30 ESRs, it is expected that DOC2AMU will enhance skills of AMU ESRs including transferrable ones; upgrade AMU doctorate\u2019s curriculum, by generalizing the innovative Doctorate Principles as a standard for all Doctoral training in AMU; reinforce AMU capacities to host talented international researchers in high standard working and improved employment conditions; intensify the cooperation and the alignment of AMU Human Resources practices between key regional academic and non-academic research and innovation players; develop new synergies on the regional territory; strengthen the innovative aspects of the Regional Doctoral programme and disseminating HR and training good practices in other Universities and Research organisations in PACA; and prioritize research projects focusing on the regional Research and Innovation Strategies for Smart Specialization strategies to create a regional leverage in terms of knowledge and innovation.", "To": ["2021-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2015-DP - Marie Sk\u0142odowska-Curie Co-funding of regional, national and international programmes (COFUND-DP)"], "Funding_scheme": ["MSCA-COFUND-DP - Doctoral programmes"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-12-01"], "Project_ID": ["713750"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2015"]}, -{"Partners": ["DWI LEIBNIZ-INSTITUT FUR INTERAKTIVE MATERIALIEN EV", "STICHTING KATHOLIEKE UNIVERSITEIT", "UNIVERSIDAD DE VALLADOLID", "AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH", "ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS", "NovioSense BV", "PEPSCAN THERAPEUTICS BV", "LIFETEC GROUP BV", "TECHNICAL PROTEINS NANOBIOTECHNOLOGY SL"], "EU_Contribution": ["EUR 3 523 738,32"], "Project_Title": ["Engineering responsive and biomimetic hydrogels for biomedical therapeutic and diagnostic applications"], "Total_Cost": ["EUR 3 523 738,32"], "Country": ["Germany", "Netherlands", "Spain", "Austria", "Greece", "Netherlands", "Netherlands", "Netherlands", "Spain"], "Project_ACR": ["BIOGEL"], "Technology_Description": "BIOGEL is set up to educate young scientists to develop innovative hydrogel chemistries and systems for biomedical applications. The first objective is to provide a platform for young researchers to undergo a well-rounded PhD education, particularly focussed on translational skills for a career focused in biomedical research and medical technology development. The second objective is to engineer functional and responsive hydrogels, which resemble specific properties of the extracellular matrix. The third objective is (i) to enhance the efficacy of medical devices by 2D biointegrative coatings that direct and orchestrate the interface to living cells and tissue and enable improved integration within the body, (ii) to advance therapeutic measures by 3D templates for tissue repair, and (iii) to enable new diagnostic tools by responsive diagnostic hydrogels. BIOGEL follows an international, interdisciplinary, and intersectoral approach organized in 9 and 8 interwoven work and training packages respectively. ", "To": ["2018-12-31, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["642687"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["ITA-SUOMEN YLIOPISTO"], "EU_Contribution": ["EUR 1 569 600"], "Project_Title": ["Biomedical Engineering and Medical Physics"], "Total_Cost": ["EUR 3 139 200"], "Country": ["Finland"], "Project_ACR": ["BioMEP"], "Technology_Description": "The BioMEP brings together complementary expertise of 8 leading research groups in Biomedical Engineering (BM) and Medical Physics (MP) across Europe to offer unique inter-disciplinary and intersectorial research and training opportunities for Early-Stage Researchers (ESRs). BioMEP aims to fulfill the demand for highly-qualified BM and MP addressing the needs of the academic, healthcare and industry sector, and thus to fully prepare them to meet the increasing demands of the European labor market. The specific objectives of BioMEP are: to attract highly-qualified international ESRs and offer them excellent expertise in diverse areas of BM and MP research and thus stimulate successful careers both in academia and beyond; to promote excellence in BM and MP research area; to foster long-term collaboration at the European level; to strengthen the international dimension of BioMEP. BioMEP is structured around five interrelated focus research areas: Musculoskeletal biomechanics, Molecular, cell and tissue engineering, Biosignals, Multimodal neuroimaging, Biomedical devices and diagnostics combined with specific research and training, internet-based training, regular seminars and summer schools. BioMEP intends to attract highly-qualified ESRs, through of a widely disseminated call for proposals, a merit-based selection process founded on international peer-review, appealing working conditions, research skills and courses specific to the area (e.g. Biomedical signal analysis, Biomechanics) and complementary training skills (e.g.entrepreneurship, ethics) to support ESRs career development. BioMEP will widen the career perspectives of ESRs by enhancing their professional experiences through the inclusion of secondments in private companies and hospitals. Thus, BioMEP will increase the national and as well European competitiveness by providing a new generation of highly-qualified experts in BM and MP able to translate basic science research results into healthcare solutions.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2015-DP - Marie Sk\u0142odowska-Curie Co-funding of regional, national and international programmes (COFUND-DP)"], "Funding_scheme": ["MSCA-COFUND-DP - Doctoral programmes"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["713645"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2015"]}, -{"Partners": ["THE UNIVERSITY OF NOTTINGHAM"], "EU_Contribution": ["EUR 1 883 520"], "Project_Title": ["The Integration of Novel Aerospace Technologies"], "Total_Cost": ["EUR 3 767 040"], "Country": ["United Kingdom"], "Project_ACR": ["INNOVATIVE"], "Technology_Description": "INNOVATIVE will enable the systematic integration of novel aerospace technologies through the training of 24 researchers through a comprehensive multidisciplinary programme. ", "To": ["2021-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2014-DP - Marie Sk\u0142odowska-Curie Co-funding of regional, national and international programmes (COFUND-DP)"], "Funding_scheme": ["MSCA-COFUND-DP - Doctoral programmes"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["665468"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2014"]}, -{"Partners": ["OULUN YLIOPISTO"], "EU_Contribution": ["EUR 2 092 800"], "Project_Title": ["Novel Imaging and Characterisation Methods in Bio, Medical, and Environmental Research and Technology Innovations"], "Total_Cost": ["EUR 4 185 600"], "Country": ["Finland"], "Project_ACR": ["I4FUTURE"], "Technology_Description": "The I4Future Programme is a novel international, interdisciplinary and inter-sectoral doctoral programme hosted at the University of Oulu. The programme is based on full exploitation of the possibilities of modern imaging and characterisation methods in cross-disciplinary work. The unique training programme aims to respond to the increasing need for skilled next-generation ESRs in the changing and demanding European job markets in industry, the public sector and academia. I4Future brings together the complementary and supplementary expertise of world-class researchers in training ESRs with interdisciplinary visions in highly relevant socio-economic research areas and state-of-the-art techniques. I4Future combines five faculties and 17 research groups of UOULU, driven together with eight international universities and nine private companies from the paper, steel, mining and medical industries as well as appliances manufacturing and four multidisciplinary public sector organisations. The I4Future programme will provide 20 ESRs with a first-hand understanding of how research develops from basic science findings to interdisciplinary innovations and commercially valuable applications. The programme exploits local, national and international strengths of the network partners at multiple levels: excellence in research, local and European cutting-edge infrastructures, collaboration networks and secondments, and wide dissemination and outreach. I4Future builds upon a critical mass of interdisciplinary, inter-sectoral and international expertise and provides a unique combination of complementary methodological approaches for high-quality training that would not be possible to implement at any site or organisation alone.", "To": ["2021-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2015-DP - Marie Sk\u0142odowska-Curie Co-funding of regional, national and international programmes (COFUND-DP)"], "Funding_scheme": ["MSCA-COFUND-DP - Doctoral programmes"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-04-01"], "Project_ID": ["713606"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2015"]}, -{"Partners": ["ACADEMISCH ZIEKENHUIS GRONINGEN"], "EU_Contribution": ["EUR 1 046 400"], "Project_Title": ["European Glaucoma Research Training Program"], "Total_Cost": ["EUR 2 092 800"], "Country": ["Netherlands"], "Project_ACR": ["EGRET"], "Technology_Description": "Glaucoma is the most common age-related neurodegenerative eye-disease in western society and one of the four major blinding eye diseases (cataract, macular degeneration, glaucoma, and diabetic retinopathy). Glaucoma is characterized by a progressive loss of retinal nerve cells. The early changes are often unnoticed by the patient. If untreated or detected too late, glaucoma will end up in blindness, yielding a profound loss of quality of life for the individual and major costs to society. In Europe, there are approximately 3 million people with glaucoma. They all need chronic medical care and, despite of that, approximately 15% of them will become blind during their lifetime.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2014-DP - Marie Sk\u0142odowska-Curie Co-funding of regional, national and international programmes (COFUND-DP)"], "Funding_scheme": ["MSCA-COFUND-DP - Doctoral programmes"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["661883"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2014"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI TERAMO"], "EU_Contribution": ["EUR 941 760"], "Project_Title": ["Food quality and food innovative strategies to prevent reproductive and eating disorders"], "Total_Cost": ["EUR 1 883 520"], "Country": ["Italy"], "Project_ACR": ["REP-EAT"], "Technology_Description": "The main objective of REP-EAT is to build up a new and innovative research and training doctoral programme (DP) in the interdisciplinary domain of food and healthy diet to deepen the impact of food quality on reproductive Health (REP) and eating disorders (EAT). In compliance with the concept of \u201cOne Health\u201d, REP-EAT DP will focus on the effect of diet determinants on both humans and animals thus implying a strict integration amongst food and life science research advances.", "To": ["2021-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2015-DP - Marie Sk\u0142odowska-Curie Co-funding of regional, national and international programmes (COFUND-DP)"], "Funding_scheme": ["MSCA-COFUND-DP - Doctoral programmes"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["713714"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2015"]}, -{"Partners": ["UNIVERSITAET BREMEN"], "EU_Contribution": ["EUR 1 831 200"], "Project_Title": ["Bremen International Graduate School of Social Sciences - Doctoral Education in Partnerships"], "Total_Cost": ["EUR 3 662 400"], "Country": ["Germany"], "Project_ACR": ["BIGSSS-departs"], "Technology_Description": "BIGSSS-departs (BIGSSS Doctoral Education in Partnerships) offers doctoral studies in a program that combines close supervision of dissertation work with demand-tailored education, both embedded in a vibrant research landscape at the Bremen International Graduate School of Social Sciences (BIGSSS). The core disciplines comprise political science, sociology, and psychology. Program participants will follow a 42 months structured curriculum including a stay abroad at an external academic partner institution or with an external non-academic partner. BIGSSS has gathered a network of some of the most prestigious international social science partner organizations. With features such as Career day or the Research day, a strong inter-sectorial exposure both in the partner network and with regards to the composition of the curriculum is an essentially new feature of BIGSSS-departs. Through a secure employment contract, the monthly pay in BIGSSS-departs will include health insurance and all German social security benefits already. Even though BIGSSS-departs is connected to a sole beneficiary (University of Bremen), it uses structures and resources of two universities.", "To": ["2021-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2015-DP - Marie Sk\u0142odowska-Curie Co-funding of regional, national and international programmes (COFUND-DP)"], "Funding_scheme": ["MSCA-COFUND-DP - Doctoral programmes"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-04-01"], "Project_ID": ["713639"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2015"]}, -{"Partners": ["INSTITUT CURIE"], "EU_Contribution": ["EUR 2 746 800"], "Project_Title": ["Institut Curie 3-i PhD Program"], "Total_Cost": ["EUR 5 493 600"], "Country": ["France"], "Project_ACR": ["IC-3i-PhD"], "Technology_Description": "The new IC-3i-PhD program of Institut Curie and its partners will produce top-level scientific knowledge by promoting basic interdisciplinary research that will be translated into novel therapeutic avenues for diagnosis and treatment. The completely re-structured, revitalized, and ambitious international \u201cTriple i\u201d PhD program is strengthened by trans- and inter-disciplinary and inter-sectorial research projects and will offer 35 international PhD positions. The program will teach PhD/Doctoral Program recipients to be excellent researchers of tomorrow; to perform research but also enhance innovation through research via established working relationships with private industry, and by supporting the creation of Small and Medium-sized Enterprises (SMEs). The objective of the doctoral programme is to offer an international, inter-disciplinary, and inter-sectorial training program for the researchers, including training-through-research (both on site and through secondments) as well as hands-on training in transferable skills. Furthermore, supporting researchers\u2019 career development via a structured career plan, and a commitment to providing fellows with the transferable skills they need, will change the standard of excellence for PhDs at the institute, and beyond. Training IC-3i-PhDs to the high standard set out in the program will ultimately lead to producing a new generation of researchers and researcher-physicians working side by side on improving health outcomes, reducing health inequalities, and promoting active and healthy ageing. Overall the proposed project will further stimulate the development of European research and human resource capacities, knowledge transfer between academic institutions and industrial stakeholders and thus strengthen the competitiveness and innovation of EU industries.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2014-DP - Marie Sk\u0142odowska-Curie Co-funding of regional, national and international programmes (COFUND-DP)"], "Funding_scheme": ["MSCA-COFUND-DP - Doctoral programmes"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2016-09-01"], "Project_ID": ["666003"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2014"]}, -{"Partners": ["UNIVERSITE PARIS DIDEROT - PARIS 7"], "EU_Contribution": ["EUR 4 708 800"], "Project_Title": ["INterdiSciPlinarity and excellence for doctoral training of International REsearchers in Paris"], "Total_Cost": ["EUR 9 417 600"], "Country": ["France"], "Project_ACR": ["INSPIRE"], "Technology_Description": "United in a Community of Universities and Institutions, called \u201cUniversit\u00e9 Sorbonne Paris Cit\u00e9\u201d (USPC), eight research universities and five research organisations located in Paris and its surroundings have decided to join their forces to build a world-class new type of university.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2014-DP - Marie Sk\u0142odowska-Curie Co-funding of regional, national and international programmes (COFUND-DP)"], "Funding_scheme": ["MSCA-COFUND-DP - Doctoral programmes"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["665850"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2014"]}, -{"Partners": ["EUROPEAN MOLECULAR BIOLOGY LABORATORY"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Structural and functional characterization of large viral and human non-coding RNA motifs involved in HIV infection"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["3DviralRNA"], "Technology_Description": "HIV infections cause 1.2Mi deaths/year worldwide at steadily-increasing rates, partly because of antiretroviral resistance and the impossibility of eradicating latent viruses. To expand our understanding of HIV pathogenesis, we need to unravel all molecular mechanisms involved in HIV progression. Large viral and human RNAs are emerging as key players in HIV infection. To characterize such RNAs, I will employ an integrated structural biology approach complemented by biochemical and functional assays in vitro and in vivo and I will address two fundamental questions: ", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-09-01"], "Project_ID": ["748759"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Seismic Ambient Noise as a proxy to investigate ICE in polar regions"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SAN-ICE"], "Technology_Description": "Polar regions are some of the least accessible regions on Earth, yet the number of continuously operating seismic stations has increased ten-fold in the last decades. When traveling in presence of ice, the seismic wavefield is reshaped and thus seismology is an ideal powerful tool to extract and monitor key ice-properties. In particular, the seismic ambient noise (SAN) wavefield is recorded continuously in time, having high temporal resolution. Compared to costly satellites and airborne campaigns commonly used to study ice in polar regions, seismology can (a) take records further back in time, (b) fill spatial gaps in satellite and airborne data and (c) fill temporal monitoring gaps. However, little is known about SAN in polar regions and how it can be used to infer ice properties. SAN-ICE will use for the first time a combination of advanced seismic data analysis and full wavefield numerical simulations to (1) characterize seismic wave propagation in presence of ice (both land and sea ice) and (2) infer ice and uppermost crustal properties using SAN. My work will consist of three work packages. First, by using novel and classical seismic methods, I will obtain high resolution maps across the whole Greenland and Antarctica of seismic velocity, density and thickness of ice and crust, completely constrained by seismic data alone. Second, I will perform time-dependent analyses of all the seismic data available up to 40 years ago from Greenland and Antarctica for monitoring ice and crustal structure changes. Third, by modeling the full wavefield and using oceanographic and satellite data, I will investigate the damping effect of sea ice on seismic waves and get new insights on sea ice changes. With this proposed work, I will explore new routes entirely based on seismology and SAN for helping to quantify ice mass changes over time, which in turn, are crucial for predictions of future sea level rise, one of the most devastating potential impacts of climate change.", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["747805"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FUNDACION AGENCIA ARAGONESA PARA LA INVESTIGACION Y EL DESARROLLO"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Beta-lactams for Tuberculosis Treatment"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["BLMs 4 TB"], "Technology_Description": "Tuberculosis (TB) is the most deadly infectious disease worldwide. TB therapy takes 6 months with unpleasant side effects that leads to poor adherence and the development of drug resistance. Patients infected with multi (MDR) or extensively (XDR) drug resistant strains must undergo longer treatments (up to 24 months) associated with even severe side effects and only 30-50% positive treatment outcomes. New treatments are urgently needed.", "To": ["2020-03-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-SE - Society and Enterprise panel"], "Coordinated_in": ["Spain"], "Activity": ["Other"], "From": ["2018-04-01"], "Project_ID": ["749058"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["PHOTANOL BV"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["Realizing a development platform for sustainable sun powered production of intermediates for chemical industry."], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["cTerF"], "Technology_Description": "The objective is to develop a base cyanobacterial cell factory for terpene precursors that can be the development platform for commercial terpene production with cyanobacteria.", "To": ["2020-01-01, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-SE - Society and Enterprise panel"], "Coordinated_in": ["Netherlands"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-01-02"], "Project_ID": ["752384"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Designing Engineers: Harnessing the Power of Design Projects to Spur Cognitive and Epistemological Development of STEM Students"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["DesignEng"], "Technology_Description": "Germany fell 76,400 engineers short in 2011. Britain falls short 55,000 engineers every year. Such deficits adversely affect Europe\u2019s R&D, patent filings, and tech production. Failure to attract women exacerbates the crisis. Europe urgently needs diverse engineers who can work collaboratively and creatively. Why does engineering struggle to attract students when architecture courses fill with women and men? Education experts (Boyer and Mitgang) say architects learn in more hands-on and effective ways than engineers. Which techniques can be transferred to make engineering more compelling?", "To": ["2020-01-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-15"], "Project_ID": ["747069"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["POLITECHNIKA POZNANSKA"], "EU_Contribution": ["EUR 227 361,60"], "Project_Title": ["Sustainability Assessment based on Decision Aiding"], "Total_Cost": ["EUR 227 361,60"], "Country": ["Poland"], "Project_ACR": ["SAbDA"], "Technology_Description": "There is a pressing need for clear and understandable information regarding the sustainability of products, companies and policies. To achieve this, one of the main priorities for the European Commission is strengthening the integration of Sustainable Development (SD) principles into the policy-making processes. For this to occur there is an impelling need for: (i) enhancing the economic profitability of businesses employing the principles of a circular economy; (ii) providing consumers with a comprehensive understanding of the impacts of products from a sustainability perspective, including environmental (e.g. energy consumption), economic (e.g. raw materials costs) and social considerations (e.g. workers\u2019 safety); and (iii) accounting for limited availability of primary resources. These objectives can be achieved if robust evaluations for the sustainability of products, companies and policies are conducted and communicated. The premier tool to support the achievement of these objectives is Sustainability Assessment (SA). Due to the importance of such societal challenges, an increasing number of criteria have been proposed to conduct a SA. A main challenge is the ability to communicate effectively the sustainability of the target alternatives in an easily understandable format, being as a score of performance, a preference class, or a ranking. Multiple Criteria Decision Aiding (MCDA) is an excellent approach to achieving these goals. Frameworks applying MCDA to SA have been proposed, but they are tailored to a set of MCDA methods and only support a limited typology of data and preference elicitation techniques. This SAbDA project will tackle these shortcomings by introducing a step-wise framework to support the development of SAs and selection of the most relevant MCDA method(s). This will include assessing the MCDA methods currently available and developing new ones, including those for evaluations at the micro (product) and meso (organization, region) levels.", "To": ["2021-09-25, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Poland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-26"], "Project_ID": ["743553"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Urban Landscapes of Power in the Iberian Peninsula from Late Antiquity to the Early Middle Ages"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ULP.PILAEMA"], "Technology_Description": "Architecture as a symbol of power has long been intentionally used to define relationships between individuals, groups, cities and governments. Substantial traces of power and authority in architecture and landscapes during Late Antiquity also demonstrate the economic and political wellbeing of newly emerging elites in Western Europe. I aim to enhance archaeological knowledge of late antique society by exploring how new topographies of power were configured. The research involves six case studies in the Iberian Peninsula. To properly integrate them in a wider archaeological context, I will look at other representative sites in England and France. Each town to be studied has substantial archaeological evidence for the study of spatial configuration of power and to generate urban patterns. Cathedrals, palaces and the construction of large ecclesiastical complexes essentially materialized the spread of early Christianity and the secular elites form the basis of what I will explore in my project. Developed new archaeologies are starting to offer alternative pictures to the traditional images of townscape revealing diverse modes of material expression, symbolic significances of places, the social usage of space, and of structural change. The focus of this research is to draw together still scattered data to chart and interpret the changing nature of life in towns through the Late Antiquity period until Early Middle Age (AD 450-800). A multi-facetted archaeological approach using Geomatic proceedings and its methods and tools (Geography Information Systems, Photogrammetry and Remote Sensing) makes it possible to reconstruct ancient landscapes generated by social actions within territories across time. A further goal is to promote this archaeological record at a European scale, emphasizing its cultural and scientific dimensions. This project will benefit substantially from new intellectual challenges and training, which will be gained at the UCL Institute of Archaeology.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["740123"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FUNDACAO D. ANNA SOMMER CHAMPALIMAUD E DR. CARLOS MONTEZ CHAMPALIMAUD"], "EU_Contribution": ["EUR 148 635,60"], "Project_Title": ["Neuronal MRI: Harnessing chemical exchange between N-Acetylaspartate and water for functional imaging of neural activity"], "Total_Cost": ["EUR 148 635,60"], "Country": ["Portugal"], "Project_ACR": ["Neuronal MRI"], "Technology_Description": "Functional MRI (fMRI) is currently the leading noninvasive modality to assess brain function in vivo. However, it relies on a surrogate marker for neural activity \u2013the hemodynamic responses following activity\u2013 which makes fMRI nonspecific and difficult to interpret. Here, we propose to advance the state-of-the-art by developing and evaluating a methodology we term neuronal fMRI (nMRI) which would enable a direct measurement of neuronal activity and its fast dynamics.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Portugal"], "Activity": ["Research Organisations"], "From": ["2017-05-01"], "Project_ID": ["753100"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSIDADE DE COIMBRA"], "EU_Contribution": ["EUR 160 635,60"], "Project_Title": ["The role of aquatic hyphomycete spores in headwater stream food webs: a food quality approach."], "Total_Cost": ["EUR 160 635,60"], "Country": ["Portugal"], "Project_ACR": ["Spor-oikos"], "Technology_Description": "The functioning of forested headwater streams relies on microbially-mediated processes ensured mainly by aquatic hyphomycetes. They are pivotal systems for human and other biotic communities as they provide water, carbon, and nutrients. The scientific objectives of the Spor-o\u00efkos project are to experimentally investigate: i) the chemical cues inducing aquatic hyphomycetes' sporulation, and ii) the functional role of aquatic hyphomycete spores in headwater food webs, both being blind spots in freshwater ecology. By applying a food quality approach and merging different scientific disciplines and theories (molecular biology, biochemical and elemental theories), this project will unveil a potential hidden pathway of nutrient and carbon (C) flow, offering new insights on the microbial contribution to large scale C fluxes. The biochemical theory studies the ecological role of essential molecules, mainly essential fatty acids and sterols. It is applied to investigate the efficiency of C transfer in trophic interactions. The elemental theory studies how the ratios of elements in organisms (e.g. C, Phosphorus and Nitrogen) shape their ecology and nutrient and energy fluxes in ecosystems. Both theories have successfully been applied to better understand the trophic interactions, and nutrient cycling in terrestrial and aquatic systems. In the last case, these theories have particularly been used to study the producer-consumer interaction in lakes, and it is just recently that they are being applied in detritus-based systems such as headwater streams. This work programme will be articulate by four experiments that have carefully been designed to progressively understand the overlooked importance of fungal spores in stream food webs, and the unknown effects of global changes (mainly eutrophication). Scientists from two high-level laboratories from two European countries will offer their expertise to train the researcher and hence open up the best possibilities for his career.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Portugal"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["746304"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["The radius of Generalized Trust among different educational groups: Are those 'most people' out-groups?"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["Trust Radius"], "Technology_Description": "European countries experience an increasing policy concern about migration\u2019s impacts on social cohesion. Social cohesion is understood as \u2018solidarity\u2019 and \u2018togetherness\u2019, often measured by generalized trust. However, studies using think aloud data demonstrate that many respondents high in generalized trust think \u2018most people\u2019 refers to people they know, whereas a high proportion of those low in trust think about strangers. Thus this project starts by recognizing that generalized trust is not necessarily the same as lack of prejudiced feelings about out-groups and aims to return to the overlooked basics: the operationalization of generalized trust, which is allegedly in decline by ethnic diversity. Furthermore, this project aims to relate attitudes to implicit measures and behavior in a controlled setting, which is ignored in previous research. Failure to accurately map the relation between generalized and out-group trust may not only lead us to possibly overestimate or underestimate their incidence in different settings, but it also conceals clear public policy directions. The first two objective of this research are: to examine the measurement similarity between generalized and out-group trust among educational groups with the aid of think aloud data and invariance testing. The third objective is to experimentally assess how well these attitudes relate to less socially desirable measures, namely reaction time in associating out-groups and in-groups with (un)pleasant words and how far research participants choose to sit away from in-groups and out-groups as social distance. Results from this project will benefit governmental agencies and academics seeking to map social cohesion by providing better quality indicators. Furthermore, the EF will enable the candidate to further develop her position as a leading academic in political psychology. This project, finally, contributes to an overarching policy area of the EU in enhancing social inclusion and inclusive growth.", "To": ["2020-02-29, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["750832"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Novel High-Power Single-Frequency Neodymium-Doped Fibre Lasers"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["NeoLaS"], "Technology_Description": "Single-frequency lasers are crucial tools for a variety of applications such as atom cooling, metrology and sensing, among others. However, to date there are still uncovered wavelength domains due to technological challenges, especially in the 900-940 nm and 455-470 nm windows for applications demanding robust systems. This project mainly focuses on the investigation of novel high-power single-frequency lasers at these wavelengths, in both continuous wave and pulsed operation. The outstanding features of fibre laser technology make it the best option to surpass the power limitations of other technologies. To date multi-Watt neodymium-doped fibre lasers have only been demonstrated in a longitudinal multimode operation using resonant cavity configurations. The development of multi-Watt-level single-frequency lasers at 910-940 nm remains a challenge not yet achieved. However, in this project we propose a radical new approach which is based on novel exotic fibres doped with neodymium in a master-oscillator power amplifier configuration. Using this new approach, the applicant has already demonstrated a single-frequency fibre laser at 922 nm with 1 W output power during a post-doc position at the host centre. This preliminary results lays a solid foundation for the success of the project. The main goal of the project is to continue pushing beyond the state of the art, developing new, robust high-power lasers in the 910-940 nm wavelength range, and in the 455-470 nm window by second harmonic generation. The project aims to develop new laser systems for both advanced atomic physics and dermatological applications. This interdisciplinary project will combine the fellow\u2019s expertise in single-frequency fibre lasers with the world-leading expertise of the host group in high-power low-noise lasers. In addition, the project will benefit from the host\u2019s well-established partnerships with academia and industry actors at the forefront of photonics in France.", "To": ["2019-04-16, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2017-04-17"], "Project_ID": ["748839"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE LYON 1 CLAUDE BERNARD", "UNIVERSITE LYON 1 CLAUDE BERNARD"], "EU_Contribution": ["EUR 2 091 000"], "Project_Title": ["Advances in Research on Theories of the Dark Universe - Inhomogeneity Effects in Relativistic Cosmology"], "Total_Cost": ["EUR 2 091 000"], "Country": ["France", "France"], "Project_ACR": ["ARTHUS"], "Technology_Description": "The project ARTHUS aims at determining the physical origin of Dark Energy: in addition to the energy sources of the standard model of cosmology, effective terms arise through spatially averaging inhomogeneous cosmological models in General Relativity. It has been demonstrated that these additional terms can play the role of Dark Energy on large scales (but they can also mimic Dark Matter on scales of mass accumulations). The underlying rationale is that fluctuations in the Universe generically couple to spatially averaged intrinsic properties of space, such as its averaged scalar curvature, thus changing the global evolution of the effective (spatially averaged) cosmological model. At present, we understand these so- called backreaction effects only qualitatively. The project ARTHUS is directed towards a conclusive quantitative evaluation of these effects by developing generic and non-perturbative relativistic models of structure formation, by statistically measuring the key-variables of the models in observations and in simulation data, and by reinterpreting observational results in light of the new models. It is to be emphasized that there is no doubt about the existence of backreaction effects; the question is whether they are even capable of getting rid of the dark sources (as some models discussed in the literature suggest), or whether their impact is substantially smaller. The project thus addresses an essential issue of current cosmological research: to find pertinent answers concerning the quantitative impact of inhomogeneity effects, a necessary, worldwide recognized step toward high-precision cosmology. If the project objectives are attained, the results will have a far-reaching impact on theoretical and observational cosmology, on the interpretation of astronomical experiments such as Planck and Euclid, as well as on a wide spectrum of particle physics theories and experiments.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["740021"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITETET I BERGEN", "UNIVERSITETET I BERGEN"], "EU_Contribution": ["EUR 2 278 884"], "Project_Title": ["Humans On Planet Earth - Long-term impacts on biosphere dynamics"], "Total_Cost": ["EUR 2 278 884"], "Country": ["Norway", "Norway"], "Project_ACR": ["HOPE"], "Technology_Description": "A critical question in Earth system science is what was the impact of prehistoric people on the biosphere and climate? There is much information about human impact through clearance, agriculture, erosion, and modifying water and nutrient budgets. Humans have greatly changed the Earth in the last 8000 years, but did humans modify the major ecological processes (e.g. assembly rules) that shape community assembly and dynamics? Did inter-relationships between processes change in response to human impact? Lyons et al. & Dietl (2016 Nature) suggest that human activities in the last 6000 years had such impacts. Dietl proposes that using past \u2018natural experiments\u2019 to predict future changes is \u201cflawed\u201d and \u201cout is the use of uniformitarianism\u201d. As using natural experiments is a common strategy and uniformitarianism is the major working concept in Earth sciences, it is imperative to test whether prehistoric human activity changed major ecological processes determining community development. To test this hypothesis, patterns in pollen-stratigraphical data for the past 11,500 years from over 2000 sites across the globe will be explored consistently using numerical techniques to discern changes in 25 ecosystem properties (richness, evenness, and diversity; turnover; rates of change; taxon co-occurrences, etc.). Patterns in these properties will be compared statistically at sites within biomes, between biomes, within continents, and between continents to test the hypotheses that prehistoric human activities changed the basic ecological processes of community assembly and that their inter-relationships changed through time. These areas provide major contrasts in human prehistory and biomes. HOPE is interdisciplinary: pollen analysis, databases, multivariate analysis, ecology, new statistical methods, numerical simulations, statistical modelling. HOPE\u2019s impact goes beyond human effects on the biosphere and extends to the very core of Earth science\u2019s basic conceptual framework.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["741413"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Nematode-based screening technology for next-generation drug discovery"], "Total_Cost": ["EUR 150 000"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["NeMatrix"], "Technology_Description": "Alternative model organisms, such as worms or flies, are getting increasingly popular in the drug discovery field, since they are proving to be suitable for replacing mammals for several aspects of the screening tests in the pre-clinical phase. In this context, one of the most interesting models is a roundworm species, named Caenorhabditis elegans. Its microscopic size, however, hinders its actual use in the field, since the protocols for its maintenance and study still completely rely on manual handling/observation techniques, definitely lacking any reproducibility and throughput standards. ", "To": ["2018-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["754375"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 1 903 685"], "Project_Title": ["Design of NanoMOFs Capsules for Drug Delivery and Bioimaging."], "Total_Cost": ["EUR 1 903 685"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["NanoMOFdeli"], "Technology_Description": "Cancer is a major health problem worldwide, being the most common cause of death after cardiovascular diseases. The major goal of new anticancer therapies is to specifically kill tumour cells while leaving healthy cells unharmed. A main challenge to achieve this aim is the development of better drugs, including novel treatments based on the use of siRNAs. These macromolecules are potentially the most powerful anti-cancer drugs that exist, but still there is no efficient way of getting them delivered specifically to the tumour. Indeed, lifetime of such molecules is generally too short and therefore need to be protected in a carrier until they are delivered into tumour target cells.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["726380"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 998 802"], "Project_Title": ["The Combined Effects of Climatic Warming and Habitat Fragmentation on Biodiversity, Community Dynamics and Ecosystem Functioning"], "Total_Cost": ["EUR 1 998 802"], "Country": ["France", "France"], "Project_ACR": ["FRAGCLIM"], "Technology_Description": "Climatic warming and habitat fragmentation are the largest threats to biodiversity and ecosystems globally. To forecast and mitigate their effects is the environmental challenge of our age. Despite substantial progress on the ecological consequences of climatic warming and habitat fragmentation individually, there is a fundamental gap in our understanding and prediction of their combined effects.", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-06-01"], "Project_ID": ["726176"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["FCIENCIAS.ID - ASSOCIACAO PARA A INVESTIGACAO E DESENVOLVIMENTO DE CIENCIAS", "FCIENCIAS.ID - ASSOCIACAO PARA A INVESTIGACAO E DESENVOLVIMENTO DE CIENCIAS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 999 275"], "Project_Title": ["Competition under (niche) construction"], "Total_Cost": ["EUR 1 999 275"], "Country": ["Portugal", "Portugal", "France"], "Project_ACR": ["COMPCON"], "Technology_Description": "Interspecific competition is arguably the best interaction to address how individual trait variation and eco-evolutionary feedbacks shape species distributions and trait evolution, due to its indirect effects via the shared resource. However, a clear understanding of such feedbacks is only possible if each contributing factor can be manipulated independently. With COMPCON, we will address how individual variation, niche width, niche construction and the presence of competitors shape species distributions and trait evolution, using a system amenable to manipulation of all these variables. The system is composed of two spider mite species, Tetranychus urticae and T. ludeni, that up- and down-regulate plant defences (i.e., negative and positive niche construction, respectively). Tomato mutant plants with low defences will be used as an environment in which niche construction is not expressed. Furthermore, tomato plants will be grown under different cadmium concentrations, allowing quantitative variation of available niches. Using isogenic lines, we will measure individual variation in niche width, niche construction and competitive ability. Different combinations of lines will then be used to test key predictions of recent theory on how such variation affects coexistence with competitors. Subsequently, mite populations will evolve in environments with either one or more potential niches, in plants where niche construction is possible or not, and in presence or absence of competitors (coevolving or not). We will test how these selection pressures affect niche width, niche construction and competitive ability, as well as plant damage. Finally, we will re-derive isogenic lines from these treatments, to test how evolution under different scenarios affects individual variation in niche width. ", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Portugal"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations"], "From": ["2017-05-01"], "Project_ID": ["725419"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Writing Jewish History: Ancient Judaism as a Political Problem in Central Europe at the Rise of the Nation State"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["AJAPP"], "Technology_Description": "AJAPP investigates the integration of religious minorities amid the rise of nation-states in Central Europe in the late modern period. Specifically, AJAPP focuses on political representation of ancient Judaism by Catholics, Jews, and Protestants throughout Prussia, Austria, and Bavaria in the course of the 19th century. The goal is to understand how portraits of the past reflected both the concerns and the conditions of modern times and, in turn, how these portraits impacted contemorary debates on issues of national, cultural, religious, and ethnic identity. It analyses how political and social differences - as opposed to strictly ethnic or cultural ones - as well as subtle prejudices manifested themselves in discussions of the past, how boundaries were made within a shared tradition, and how identities were configured in regional and national entities. This period is especially imortant as this was a time when distinct regions were negotiating their political relationships to one another (often with violence), when public discourse was debating which communities had which stakes in and rights to the political realm, and when the past became especially contested territory for determining which groups were insiders and which ones were outsiders. Given the current rise in regionalism, nationalism, and right-wing extremism across Europe, AJAPP addresses a central problem palpable on the local, international, and global levels today. It reveals how implicit assumptions inscribe the conceptualisation of the past, which then find their way back into the present.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["749628"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF NEWCASTLE UPON TYNE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Spaces of Anti-Muslim Acts in the Greater Paris and Greater London regions"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SAMA"], "Technology_Description": "Social and political debates have repeatedly shown that we are now in a new religious era primarily marked by diversity. The religious diversity of European society \u2013 and in particular the visibility of Muslims in the public space \u2013 reveals that the geographical space is a key factor in the study of anti-Muslim discrimination. Indeed, Islamophobia is very much present and has intensified especially since the armed attack of Charlie Hebdo publishing offices (a French satirical magazine) in January 2015. By analysing the spatial effects of Islamophobia, we seek to more effectively assess the impact of Muslim presence throughout European society, and in particular in France and United Kingdom. More exactly in the SAMA project, I will identify the spaces where anti-Muslim acts have occurred, the spatial practices and the scales of belonging of these discriminated people, and the intersectional dimension of Islamophobia in both the Greater Paris and Greater London regions. In addition to recording the highest levels of anti-Muslim acts , these conurbations are also \u201csocio-spatial laboratories\u201d that offer a useful context for exploring and understanding the dynamics that revolve around religious discrimination. To do this, the researcher - Dr Kawtar NAJIB - is moving from France to Newcastle University in United Kingdom in order to undertake a research on \u201cspaces of anti-Muslim acts in the Greater Paris and Greater London regions\u201d. This project will offer significant insights for the fight against racism and hate crimes in Europe. The researcher will gain research expertise in Islamophobia, social geographies, inter-European comparative research and GIS (Geographical Information Systems).", "To": ["2018-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["703328"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["GOETEBORGS UNIVERSITET"], "EU_Contribution": ["EUR 173 857,20"], "Project_Title": ["Experimental Study of Three-dimensional Dynamics of Active Particles"], "Total_Cost": ["EUR 173 857,20"], "Country": ["Sweden"], "Project_ACR": ["ACTIVEMOTION3D"], "Technology_Description": "Active particles are microscopic objects capable of self-propulsion. Examples include natural microorganisms, e.g. motile bacteria, chemotactic cells, and artificial colloidal microswimmers. From the fundamental side, their study can shed light on the far-from-equilibrium physics underlying the adaptive and collective behavior of microscopic biological entities. From the more applied side, they provide tantalizing options to perform tasks not easily achievable with other available techniques, such as the targeted localization, pick-up and delivery of microscopic cargoes, e.g., in drug delivery, bioremediation and chemical sensing. Despite the ever-growing interest that active particles have arisen in the scientific community, almost all experimental studies have focused on quasi-two-dimensional investigations, mainly because of limitations in the employed microscopic techniques. Nevertheless, the three-dimensional (3D) dynamics and behavior of active particles can be qualitatively different, as has already been shown by numerical and theoretical studies; this is particularly true when considering active particles moving in 3D complex and crowded environments. With this project, I will fill this gap by developing an experimental technique capable of investigating the motion of active particles in 3D. First, I will implement a state-of-the-art 3D super-resolution microscope (high-frame rate, large field of view). Then, I will use it to characterize the 3D motion of single active particles in homogenous environments. Finally, I will study their motion in complex and crowded environments similar to the ones that can be found in nature or in applications; this will permit me to explore and develop effective strategies to control the motion of active particles in these environments. This will pave the way towards a deeper understanding of the behavior of active particles and also towards realistic applications.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["745823"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF NEWCASTLE UPON TYNE", "UNIVERSITY OF NEWCASTLE UPON TYNE"], "EU_Contribution": ["EUR 2 023 119"], "Project_Title": ["Assisting Coral Reef Survival in the Face of Climate Change"], "Total_Cost": ["EUR 2 023 119"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["CORALASSIST"], "Technology_Description": "CORALASSIST spans the disciplines of evolutionary biology, restoration ecology and proteomics and examines the role assisted gene flow (AGF) can play in sustaining biodiversity and ecosystem services in the face of climate change. AGF involves the deliberate movement of individuals or gametes within their natural range to facilitate adaptation to environmental change. Corals reefs provide an excellent model for testing AGF as a conservation tool because reef building corals are foundation species and are highly vulnerable to thermal stress. Selective breeding and translocation of thermotolerant individuals may lead to reductions in recipient population fitness due to resource trade-offs with other fitness traits, such as growth and fecundity. The overall aim of CORALASSIST is to establish the feasibility of implementing AGF in coral reef ecosystems using a combination of selective breeding, proteomics and innovative translocation techniques. CORALASSIST will address four primary questions: 1) Are there resource trade-offs between increased thermotolerance and other fitness traits in corals? 2) Which physiological and proteomic traits correlate with increased individual thermotolerance in corals? 3) Are phenotypic traits for thermotolerance heritable? 4) Can AGF and selective breeding lead to persistent shifts in thermotolerance in recipient populations? Phenotypic traits will be measured in permanently tagged individuals within selected coral populations to examine the relationships between thermotolerance and key fitness attributes. For the first time, state of the art proteomic approaches will be used to elucidate the physiological basis for increased levels of thermotolerance in corals. Innovative translocation methods will be used in tandem with selective breeding techniques to carry out the first long term assessment of heritability of thermotolerance and to test the feasibility of large scale AGF to assist conservation of coral reef ecosystems.", "To": ["2022-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["725848"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["CONSIGLIO NAZIONALE DELLE RICERCHE"], "EU_Contribution": ["EUR 2 746 800"], "Project_Title": ["INnovative Life sCIence Phd Programme in South ITaly"], "Total_Cost": ["EUR 5 493 600"], "Country": ["Italy"], "Project_ACR": ["INCIPIT"], "Technology_Description": "INCIPIT is a novel international PhD programme, which aims at providing innovative multidisciplinary and intersectoral training in Life and Biomaterial Sciences. Currently, there are several nodes of excellence in the South of Italy, capable of providing competitive scientific training. However, comprehensive training programmes addressing multidisciplinarity, transferable skills and internationalization are lacking. INCIPIT addresses this gap by pooling the different and complementary expertise of 8 research institutes (from biology and genetics to statistics, engineering, computer science, chemistry and medicine) of the Consiglio Nazionale delle Ricerche (CNR), as well as the competencies of 3 Doctoral Schools and several academic, non-profit and industrial Partner Organizations. INCIPIT will apply transparent and equitable selection procedures, based on merit and on equal opportunities to recruit 35 Early Stage Researchers. INCIPIT will guarantee 1) a supportive, stimulating and multidisciplinary research environment to carry out the research projects; 2) theoretical and practical courses on developmental/stem cell biology and regenerative medicine, structural biology and biocatalysis, human disease mechanisms, cancer development and treatment, metabolism and inflammation, drug design, discovery and delivery, and computational biology; 3) a comprehensive training on transferable skills on several topics, from communication, project management, clinical trials, the principle of the 3 Rs for the use of animals, to intellectual properties and entrepreneurship; and 3) exposure to the industry sector. The ultimate goal is to train the next generation of researchers to become a very attractive source of employment in both the Italian and European labour markets. INCIPIT will be a pilot project, paving the way to the consolidation in the South of Italy of an international PhD programme, with close collaboration among the CNR, the Universities and the industrial sector.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2014-DP - Marie Sk\u0142odowska-Curie Co-funding of regional, national and international programmes (COFUND-DP)"], "Funding_scheme": ["MSCA-COFUND-DP - Doctoral programmes"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations"], "From": ["2016-01-01"], "Project_ID": ["665403"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2014"]}, -{"Partners": ["INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT", "WEST AND CENTRAL AFRICAN RESEARCH AND EDUCATION NETWORK", "GEANT LIMITED", "GROUPEMENT D INTERET PUBLIC POUR LERESEAU NATIONAL DE TELECOMMUNICATIONS POUR LA TECHNOLOGIE L ENSEIGNEMENT ET LA RECHERCHE", "CENTRE DE COOPERATION INTERNATIONALE EN RECHERCHE AGRONOMIQUE POUR LEDEVELOPPEMENT - C.I.R.A.D. EPIC", "SIGMA ORIONIS SA", "BRUNEL UNIVERSITY LONDON", "THE UBUNTUNET ALLIANCE FOR RESEARCH AND EDUCATION NETWORKING", "COOPERACION LATINOAMERICANA DE REDES AVANZADAS"], "EU_Contribution": ["EUR 1 217 982,50"], "Project_Title": ["TransAfrican Network Development"], "Total_Cost": ["EUR 1 217 982,50"], "Country": ["France", "Ghana", "United Kingdom", "France", "France", "France", "United Kingdom", "Netherlands", "Uruguay"], "Project_ACR": ["TANDEM"], "Technology_Description": "The TANDEM project aims to create favourable conditions for WACREN (West and Central African Research and Education Network) to be able to participate in the forthcoming AfricaConnect project extension and to draw maximum benefit from it, and thereby to ensure WACREN\u2019s integration into the global Research and Education networking community. TANDEM long-term goal is to make it possible for researchers and academics to contribute with their peers around the world to the socio-economic development of the West and Central African Region. To this end, TANDEM is structured around three objectives:", "To": ["2017-04-30, closed project"], "Meta": [""], "Topic_s": ["INFRASUPP-7-2014 - e-Infrastructure policy development and international cooperation"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Other", "Other", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other"], "From": ["2015-05-01"], "Project_ID": ["654206"], "Call_for_Proposal": ["H2020-INFRASUPP-2014-2"]}, -{"Partners": ["CENTRALESUPELEC"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["scalaBle and grEen wireleSs coMmunications for a sustAinable netwoRked socieTy"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["BESMART"], "Technology_Description": "The goal of the project is to develop energy-efficient and scalable designs for distributed mobile networks operated by renewable energy sources, and with very limited signaling overhead and computational complexity. The project will design wireless networks, composed by smart nodes, which are able to perform the following tasks:\u2028", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["749336"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["DANMARKS TEKNISKE UNIVERSITET"], "EU_Contribution": ["EUR 212 194,80"], "Project_Title": ["High Current All Printed Transistors"], "Total_Cost": ["EUR 212 194,80"], "Country": ["Denmark"], "Project_ACR": ["HCAPT"], "Technology_Description": "The fast evolution of printed electronics, with the photovoltaic technology in primis, is requiring the presence of a valid transistor alternative to the traditional one. The realization of a high current roll-to-roll transistor will interconnect all the different technologies so far developed with this low cost and high throughput method. Our aim is to develop a roll-to-roll transistor capable to of modulate modulating the current to levels that where has not been achieved so far. The fabrication of the transistor will be done considering the lowest environmental impact possible, and containing energy consumption with a temperature below 150 \u00b0C. This high current (~mA) transistor will be able to support and assist other technologies and will also be the base for logics and sensing application.", "To": ["2017-04-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-05-01"], "Project_ID": ["659747"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["CENTRE DE COOPERATION INTERNATIONALE EN RECHERCHE AGRONOMIQUE POUR LEDEVELOPPEMENT - C.I.R.A.D. EPIC", "CENTRE DE COOPERATION INTERNATIONALE EN RECHERCHE AGRONOMIQUE POUR LEDEVELOPPEMENT - C.I.R.A.D. EPIC", "INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT"], "EU_Contribution": ["EUR 1 993 281"], "Project_Title": ["Revolutionizing Insect Control"], "Total_Cost": ["EUR 1 993 281"], "Country": ["France", "France", "France"], "Project_ACR": ["REVOLINC"], "Technology_Description": "EFSA recently prohibited 75% of insecticides to account for their toxicity and ecotoxicity. Moreover, the spread of insecticide resistance and invasion of Europe by new tropical vectors and pests require the development of alternative biological techniques.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations"], "From": ["2016-09-01"], "Project_ID": ["682387"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT"], "EU_Contribution": ["EUR 178 603,20"], "Project_Title": ["Understading the Maize Epigenome and its Role in Development"], "Total_Cost": ["EUR 178 603,20"], "Country": ["France"], "Project_ACR": ["EPIMAIZE"], "Technology_Description": "Phenotypes are largely determined by genetic factors. However, a given genotype can give rise to very distinct phenotypes, as exemplified by the diversity of cell types in multicellular organisms. This phenotypic plasticity results from epigenetic changes; that is, reversible modifications to the DNA molecule and its associated proteins that modulate gene expression patterns. Epigenetic changes are critical to the establishment of developmental programs, but also to adjust transcription in response to the environment. The latter is particularly important for plant adaptation: owing to a sessile (immobile) lifestyle, plants cannot run away from adversity, and thus adapt to their environment by tuning gene expression in response to changing conditions. Most epigenetic information is erased from one generation to the next, so that new organisms start their life cycle with a \u201cfresh\u201d potential. However, there are instances in nature of heritable epigenetic marks that can be transmitted to the next generation. Thus, owing to their role in shaping gene expression, and the potential for heritable changes, epigenetic factors are of great interest for plant breeders, in their quest for adaptable, high yielding phenotypes. Most of our current understanding of epigenetic processes in plants has been developed in Arabidopsis, a key model system. However, the Arabidopsis epigenome is rather idiosyncratic, and this knowledge might translate poorly to crops. Here, we will use an interdisciplinary approach combining original genetic materials and bioinformatics to analyze epigenetic regulatory pathways in maize, with a focus on reproductive development. Maize is an important model plant, with a large and dynamic epigenome much more typical of crops. It is also a crop of great economic importance. Better understanding the epigenome of maize will open the door to the manipulation of key agronomic traits, including reproductive development, which is under strong epigenetic influence.", "To": ["2017-07-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2015-08-01"], "Project_ID": ["658900"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["FONDS NATIONAL DE LA RECHERCHE"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Luxembourg EU Presidency Conference 2015 on MSCA COFUND, 10-11 December 2015"], "Total_Cost": ["EUR 191 250"], "Country": ["Luxembourg"], "Project_ACR": ["MSCA2015 - COFUND"], "Technology_Description": "Under Luxembourg's EU presidency in the second half of 2015, the National Research Fund (FNR) is organising a high visibility international conference on the theme of COFUND in the framework of the Marie Sklodowska-Curie Actions. ", "To": ["2016-01-31, closed project"], "Meta": [""], "Topic_s": ["MSCA - MSCA"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Luxembourg"], "Activity": ["Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2015-07-01"], "Project_ID": ["692700"], "Call_for_Proposal": ["H2020-Adhoc-2014-20"]}, -{"Partners": ["BIRKBECK COLLEGE - UNIVERSITY OF LONDON"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Reasonable Doubt: An epistemological and psychological approach"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ReaDoubt"], "Technology_Description": "The purpose of this research is to shed light on the nature and dynamics of doubt and confidence in complex epistemic decision-making, through a study of the notion of reasonable doubt. While doubt is considered a rational virtue, waiting until complete certainty before accepting and acting upon a given hypothesis is unreasonable in many contexts. Given some evidential support for the hypothesis, the threshold beyond which acceptance rather than doubt is the reasonable option seems to depend on the decisional context (particularly the cost of a possible error): jurors in criminal trials should thoroughly consider alternative scenarios before convicting a defendant; doctors or policy-makers, however, may have to take action upon less strongly confirmed hypotheses, depending on the relative costs and benefits of action/inaction. Such a decision-theoretic view of reasonable doubt relies on the assumption that the consequences of an hypothesis are exogenous to the rational evaluation of its evidential support: one first updates one\u2019s degree of belief in view of the evidence, and then assesses whether, given the context, the hypothesis is beyond reasonable doubt (i.e. should be accepted and acted upon). But is it the case that agents\u2019 degrees of confidence in a hypothesis, and their weighing of various pieces of evidence, are impermeable to the decisional context? Is the juror\u2019s actual belief independent from her having to bring a consequential verdict? This research aims to study the epistemological norms of reasonable doubt, taking account of the psychological reality of the agents\u2019 reasoning. The main objective of the fellowship is to develop an original empirical research programme, testing the effects of the consequentiality of epistemic decisions on reasoning. This interdisciplinary project requires the candidate, an expert philosopher, to acquire experimental skills and knowledge in psychology, under the supervision of a specialist in the psychology of reasoning.", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["660187"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITY OF LEEDS"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Catchments under Pressure: Ecosystem Service Solutions"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["CuPESS"], "Technology_Description": "Catchments are under pressure from impacts on demand and supply and within these constraints water resource managers are challenged to meet multiple and often competing values. The ecosystem services (ES) approach has attracted policy interest as it connects natural capital and the ES flows it supports with human wellbeing. There exists a policy window to translate detailed case study assessment into workable solutions for catchment management in times of change in Europe and beyond. ES research to protect and foster sustainable management of natural resources and ecosystems and the multiple ES they supply fits within the Horizon 2020 programme on Societal Challenges. ", "To": ["2017-06-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-07-01"], "Project_ID": ["659449"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["VASTRA GOTALANDS LANS LANDSTING"], "EU_Contribution": ["EUR 708 000"], "Project_Title": ["Mobility for Regional Excellence 2020"], "Total_Cost": ["EUR 1 416 000"], "Country": ["Sweden"], "Project_ACR": ["MoRE2020"], "Technology_Description": "MoRE2020 is a continuation and further development of the FP7-Marie Curie-COFUND programme called \u201cMobility for Regional Excellence\u201d (MoRE), which Region V\u00e4stra G\u00f6taland was granted in December 2013 (grant agreement no 608743). The half-term external evaluation of the MoRE programme indicated very positive results. ", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2016 - Co-funding of regional, national and international programmes"], "Funding_scheme": ["MSCA-COFUND-FP - Fellowship programmes"], "Coordinated_in": ["Sweden"], "Activity": ["Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2017-05-01"], "Project_ID": ["754412"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2016"]}, -{"Partners": ["CORK INSTITUTE OF TECHNOLOGY", "UNIVERSITY OF ULSTER", "FTK FORSCHUNGSINSTITUT FUR TELEKOMMUNIKATION UND KOOPERATION EV", "GLOBIT-GLOBALE INFORMATIONSTECHNIKGMBH", "INMARK EUROPA SA"], "EU_Contribution": ["EUR 504 000"], "Project_Title": ["Sensor Enabled Affective Computing for Enhancing Medical Care"], "Total_Cost": ["EUR 504 000"], "Country": ["Ireland", "United Kingdom", "Germany", "Germany", "Spain"], "Project_ACR": ["SenseCare"], "Technology_Description": "This project brings together a diverse group of subject matter experts from industry and academia under one umbrella, with the main aim of enhancing and advancing future healthcare processes and systems using sensory and machine learning technologies to provide emotional (affective) and cognitive insights into patients well-being so as to provide them with more effective treatment across multiple medical domains. The objective is to develop technologies and methods that will lessen the enormous and growing health care costs of dementia and related cognitive impairments that burden European citizens, which is estimated to cost over \u20ac250 Billion by 2030 [1]. ", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-01-01"], "Project_ID": ["690862"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 1 726 560"], "Project_Title": ["DOCtoral training programme in Functional Advanced Materials"], "Total_Cost": ["EUR 3 453 120"], "Country": ["Spain"], "Project_ACR": ["DOC-FAM"], "Technology_Description": "DOC-FAM is a COFUND Doctoral Programme with a duration of 60 months presented by the Spanish National Research Council (CSIC) and coordinated through the Institute of Materials Science of Barcelona (ICMAB). The main aim of the programme is the training of 22 early-stage researchers during 36 months each as the next-generation of scientists in the exciting field of Functional Advanced Materials, while at the same time offering a complete training experience to the recruited fellows. This doctoral programme builds up on the recent award obtained by ICMAB as one of the 22 \u201cSevero Ochoa Centres of Excellence\u201d, an award given by the Spanish Government that recognizes institutions from all areas of knowledge that perform cutting-edge research at world standards. The award as \u201cSevero Ochoa Centre of Excellence\u201d to develop \u201cSmart Functional Materials for Social Grand Challenges\u201d (FUNMAT, 2016-2019) demonstrates the outstanding international scientific leadership of ICMAB in the field of Advanced Functional Materials and Nanomaterials. The aim of the research programme offered in DOC-FAM is to complement the training aspects of FUNMAT by offering the recruited fellows an excellence training programme in the bourgeoning field of Functional Advanced Materials through an interdisciplinary, intersectorial and international approach with the support of several partner organisations from the area, four of them contributing to the co-funding of the doctoral programme. The designed training programme combines different types of activities that will enhance their research and personal skills, providing them with new career perspectives.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2016 - Co-funding of regional, national and international programmes"], "Funding_scheme": ["MSCA-COFUND-DP - Doctoral programmes"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["754397"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2016"]}, -{"Partners": ["THE QUEEN'S UNIVERSITY OF BELFAST"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["FUTURE-PROOF: Wide Area Monitoring and Protection Systems for the Future Grid"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["FUTURE-PROOF"], "Technology_Description": "This project seeks to advance the state-of-the-art in wide-area power system monitoring and protection systems, a critical component of future power systems, and vital to achieving the EU vision of a European Energy Union that delivers secure, affordable and climate-friendly energy. Crucially, the fellowship will bring together the complementary expertise of the applicant on power system protection, with the host organisation\u2019s state-of-the-art wide-area monitoring infrastructure, and technical expertise in measurement technology, machine learning and big data analysis, enabling innovative research at the interface between these domains. Outputs will take the form of peer-reviewed journal articles and international conference papers setting out algorithms, and methodologies for robust and scalable monitoring and protection of future grids, and a power industry engagement workshop for knowledge transfer to key stakeholders. ", "To": ["2020-02-14, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-02-15"], "Project_ID": ["751893"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "FIBERCRYST SAS", "JUSTUS-LIEBIG-UNIVERSITAET GIESSEN", "FYZIKALNI USTAV AV CR V.V.I", "UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA", "PRYSMIAN", "Intelligentsia Consultants S\u00e0rl"], "EU_Contribution": ["EUR 922 500"], "Project_Title": ["International and intersectoral mobility to develop advanced scintillating fibres and Cerenkov fibres for new hadron and jet calorimeters for future colliders"], "Total_Cost": ["EUR 1 093 500"], "Country": ["Switzerland", "France", "France", "Germany", "Czech Republic", "Italy", "Italy", "Luxembourg"], "Project_ACR": ["INTELUM"], "Technology_Description": "Currently, new concepts are being considered for hadron and jet calorimetry in high energy physics experiments, in order to improve the energy resolution of these detectors by a factor of at least two. This is a prerequisite for future studies at the high luminosity, large hadron collider as well as at future electron and proton colliders. Amongst the few concepts being proposed, scintillating and \u010cerenkov fibres are considered very promising candidates.", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Switzerland"], "Activity": ["Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-03-01"], "Project_ID": ["644260"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 270 918"], "Project_Title": ["Toward a new generation of Ecological Assessment tools for the Management Coastal environment"], "Total_Cost": ["EUR 270 918"], "Country": ["France"], "Project_ACR": ["TEAM-Coast"], "Technology_Description": "Marine coastal areas have a considerable socio-economic importance and provide multiple services to Humankind (fisheries, nutrient cycling etc.). However, these environments are subjected to multiple anthropogenic pressures that are profoundly modifying benthic communities (i.e. organisms living on, in, or near the seabed as invertebrates, algae, bacteria etc.) that control most coastal ecosystem services. The TEAM-Coast project aims to develop a new generation of tools, based on emerging environmental genomics approaches (i.e. the study of genetic material retrieved in environmental samples), to investigate responses of coastal communities to stressors and assist stakeholders to make informed decisions regarding the balance between human activities and ecological integrity of coastal environments. Preserving efficiently these environments requires: 1) to integrate all coastal biodiversity in studies and models, a large portion being generally excluded due to technical and financial constraints; 2) to treat anthropogenic pressures in a integrated way to understand the full ecological ramifications of the multiple stressors in interaction on the structure and functioning of communities; 3) to rank the relative importance of these stressors to prioritize actions to lead. This project proposes thus to take advantage of the promises of environmental genomics to characterize the whole range of benthic communities over broad scales, at a unprecedented level of details and in a standardised, rapid and cost-effective way. These approaches will be implemented at the seascape scale to disentangle and understand ecological ramifications of multiple human-induced stressors on structure and diversity of benthic communities. Data will be then combined with cutting-edge statistical tools to identify key stressors and develop innovative management strategies. As such, outcomes of TEAM-Coast will lead to major advances for monitoring and management of European coastal environments.", "To": ["2021-07-15, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2018-07-16"], "Project_ID": ["750570"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Solid-State Multi-Photon Sources for Larger-Scale Quantum Optics and Photonics"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["SMuPhoS"], "Technology_Description": "Optical quantum technologies are at the forefront of a forthcoming second quantum revolution, where advances in quantum photonics at the single-photon level are enabling new technologies at accelerating pace: from applications for secure quantum communication, to the realization of quantum simulation and quantum computation protocols. The scaling of quantum photonics, however, has long been restrained by low efficiencies in current photon sources, what limits the complexity of the protocols that are being demonstrated. The host team has very recently succeeded in the fabrication of solid-state single-photon sources about 20 times more efficient than current alternatives. These sources have reached the best possible performance in terms of purity and indistinguishability, as required for scalable applications. In this proposal, the high performance of these devices is combined with the expertise in quantum optics of the applicant to advance the state-of-the-art in quantum photonics to the efficient and high-rate manipulation of multiple single-photons. A new era of larger-scale quantum photonics will be attained by enabling the manipulation of multiple photons past the qubyte threshold of 8 photons. The project will include the demonstration of 10-photon sources with sub-Hertz detection rates; the implementation of heralded entangling gates run at unprecedented rates; as well as the demonstration of multi-photon interference with up to 8-photons in a Boson Sampling machine. This project will thus importantly advance upon the complexity of current multi-photon research, opening a new era of solid-state based quantum optics and photonics.", "To": ["2019-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2017-12-01"], "Project_ID": ["750886"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Resource Sensitive Quantum Computing"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["ResQu"], "Technology_Description": "Quantum Computing has been a subject of huge interest in recent years, from researchers and the general public alike, due to its intriguing potential for applications which will forever be beyond the reach of classical computing. Despite recent progress in both experimental and theoretical techniques, difficulties in communicating the needs and results of these respective camps has resulted in a lack of major implementable applications for near-term technologies. This action aims to change the field multilaterally, from developing novel tools to deal with critical practical issues hindering implementation through to a first resource sensitive theoretical approach to finding applications with technological practicalities at its core.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["750523"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE DE LILLE II - DROIT ET SANTE"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Glucotanycytes: a role for hypothalamic barriers in the control of metabolism by peripheral glucose"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["GLUCOTANYCYTES"], "Technology_Description": "\"The escalating epidemic of obesity, type-2 diabetes and metabolic syndrome represents one of the most pressing and costly biomedical challenges confronting modern society. The impaired action of peripheral hormones on brain circuits controlling feeding and energy homeostasis, also known as \"central hormone resistance\", is increasingly recognized as playing a role in the pathophysiology of these disorders. The host laboratory has raised the groundbreaking notion that tanycytes, a specific type of hypothalamic glial cells, act as \"gatekeepers\" that regulate the access of blood-borne signals to the hypothalamus, and in particular, their vesicular transport into the cerebrospinal fluid, from where they enters other metabolic-hormone-sensitive regions. The overall objective of this proposal is to further develop this highly original angle by using state-of-the-art approaches to i) gain new insights into the molecular mechanisms underlying structural changes in the tanycytic barrier in response to fluctuating concentrations of circulating glucose, and determine how these processes are altered in animal models with acquired type-2 diabetes, and ii) explore the possibility that tanycytes are involved in the shuttling of circulating glucose into the cerebrospinal fluid (CSF) and that the tanycytic expression of the NMDA receptor plays a role in this process. This research promises to shed new light on the molecular mechanisms used by the hypothalamus to integrate key peripheral signals and coordinate energy homeostasis. The results will pave the way for the development of new treatment strategies to overcome hormone resistance in human obesity and associated metabolic syndromes.\"", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["748134"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN"], "EU_Contribution": ["EUR 175 866"], "Project_Title": ["For a better understanding and design of ferroelectric photovoltaics: First-principles study of opticalabsorption and charge-carrier transport at ferroelectric domain walls in BiFeO3"], "Total_Cost": ["EUR 175 866"], "Country": ["Ireland"], "Project_ACR": ["FERROVOLT"], "Technology_Description": "The goal of this project is to help find the rules for a domain-wall engineering that optimizes photovoltaic efficiency of potential future-generation ferroelectric solar cells. The material to be studied is BiFeO3 as the most promising photovoltaic ferroelectric material known. Does the photovoltaic effect in BiFeO3 occur at the domain walls or in the bulk? What does it take a domain-wall to conduct electrons? The project aims", "To": ["2019-06-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-15"], "Project_ID": ["746964"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 173 212,20"], "Project_Title": ["Mobility in situ: Debating emigration and return in Western Mali"], "Total_Cost": ["EUR 173 212,20"], "Country": ["France"], "Project_ACR": ["MOBILIMA"], "Technology_Description": "Located in Western Mali, at the junction with Senegal and Mauritania, the area of Kayes has a long history of sustained involvement in transnational migration, notably towards France. The region bears the material and social imprints of decades of international migration in its infrastructures, buildings, family relations, and local notions of success and failure. Though this migration and its social effects have been the topic of a wide range of studies, the local understandings and discussions of these dynamics have been under-researched. Dwelling on developments in anthropology and African studies that highlight the importance of local expressive practices, this project focuses on three arenas where emigration and, more specifically, return have been debated: a village created by returnees in 1977; a local radio initiated by emigrants in 1987; individual trajectories of returnees from France to one village. In each field-site, biographical narratives will be combined with corpora of local productions of distinct sorts: personal documents such as family letters or cassettes; public discourses such as listeners\u2019 letters to the radio and songs; and personal archives including photographs. The project will discuss the issue of return, a heavily politically and morally loaded one, by bringing together the individual and collective stories of returnees from distinct generations (those returning as adults in the 1970s and those returning in the 2000s), and the public discourses of each time. It will also question the way it is currently memorialized. While contributing to anthropological discussions on return migration, the ambition of the project is also to offer a better understanding of a key zone of emigration to Europe. Since the European Union is committed to address the root causes of migration, and funds initiatives to prevent migration, providing knowledge on local debates on migration can offer resources for designing effective programs in this field.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["749223"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSIDAD PABLO DE OLAVIDE"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Whispering the language of the neurons to restore vision"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["NeuroBaBEL"], "Technology_Description": "Visual neuroprostheses or the bionic eyes, aim to restore patterned vision to the blind by electrically stimulating the remaining neurons in the visual system. The ultimate goal of bionic eye research as a means of treating vision loss is the capacity to reproduce the same neural messages that travel between the eye and the brain of normal vision. The visual system 'sees' the world by way of sending signals to the brain that indicate transitions from 'light ON to light OFF' and from 'light OFF to light ON' wherever a transition exists. Despite the remarkable progress over the last decade, until recently, visual neuroprostheses could only stimulate both the \u2018ON-to-OFF\u2019 and the \u2018OFF-to-ON\u2019 pathways simultaneously, sending confusing neural messages to the brain. Selective activation has been demonstrated in vitro while validated computational models predict that neural signals can be modulated by affecting these waveforms. This proposal aims to investigate, in a functional model of the disease (Royal College of Surgeons rats), new ways to preferentially activate the aforementioned visual pathways using amplitude- and frequency- modulated signals combined with low-power noise. It is expected that the resulting neural encoding to be more natural and to therefore improve the perception of the bionic eye recipients. Two strategies will be adopted: (1) acute electrophysiology experiments to obtain optimal stimulation parameters, and (2) chronic studies in behaving animals with retinal degeneration subjected to classical conditioning. This is a highly multidisciplinary proposal that includes a comprehensive plan for the dissemination of the results among the scientific community and the general public, while providing opportunities for industrial engagement. The fellow will be immersed in a motivating research environment and will be exposed to a series of training and networking activities which provide an excellent ground for future career perspectives.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["746526"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE"], "EU_Contribution": ["EUR 251 857,80"], "Project_Title": ["USLAMISM:The United States and Political Islam: A Historical and Contemporary Perspective."], "Total_Cost": ["EUR 251 857,80"], "Country": ["United Kingdom"], "Project_ACR": ["USLAMISM"], "Technology_Description": "At a time when various Islamist groups are in close proximity to power, this project aims to examine the relations between the US and forces aligning themselves with Islamism . It is meant to understand the mechanisms of US policy towards this ideology. What are the issues arising from the diplomatic relations linking the US power and the representatives of an ideology traditionally opposed to them? What conceptions of Islamism \u2013both historical and contemporary\u2013 has been guiding US foreign policy? The research process will be structured along two dimensions. The first is a historical investigation based on State Department and Presidential archives and sources handed down by US foreign policy practitioners dealing with Islamism over several decades. The second dimension consists of an examination of the contemporary state of play using interviews, discourse analysis and a study of US foreign policy actions towards Islamist forces. USLAMISM is original in three ways. ", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["750833"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF HUDDERSFIELD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["using Virtual Reality and Archaeoacoustic Analysis to Study and exhibit Presence"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["VRAASP"], "Technology_Description": "Unusual acoustic signatures of ancient or historical spaces, such as the West Kennet Long Barrow in England; caves in northern Spain containing prehistoric art; or Sculptor's Cave in Scotland, have captured the public imagination for centuries. Attentive listeners often hear or feel a presence or resonance within such acoustic spaces, sometimes described as an otherness, a shimmer or glow, or an audio-visual aesthetic experience of the space. There is evidence that this sense of presence is brought on by the perceptual conflation of where and what streams of information in the brain. Other acoustic incongruities (such as infrasound) play a role in the experience of spaces and the acoustic experience of presence contributes to the phenomenology of historical and archaeological sites. The perception of presence is especially common in historically sacred locations (and shimmer is a characteristic descriptor of the spiritual realm), and thus acoustic analysis of the phenomenology of presence provides insight into the source of this experience. Acousticians, composers, and acoustic archaeologists have studied acoustic phenomena, and archaeologists have compiled 3D models of archaeological sites for cultural preservation and exhibition purposes. The ER will use these technologies to engage in creative practice-led research on the phenomenology and acoustic archaeology of space. This research will contribute new knowledge on the phenomenology and psychoacoustics of archaeological spaces, and will also improve virtual archaeological spaces by imbuing them with their original sense of presence. Through this project the ER will develop skills in 3D visual and acoustical modelling, VR simulation, numeracy, data analysis, sound reinforcement, publication preparation, presentation, and dissemination. Throughout the fellowship, the ER will undertake field work at 5 archaeological sites, publish 1 paper and 1 studio report, present at 2 conferences, and organise a performance.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Denise Ogden", "Tel.: +44-1484-473192", "Fax: +44-1484-472682"], "From": ["2017-10-01"], "Project_ID": ["750618"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["VYSOKE UCENI TECHNICKE V BRNE", "VYSOKA SKOLA BANSKA - TECHNICKA UNIVERZITA OSTRAVA", "CEMMAC AS", "ZPSV, AS", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 558 000"], "Project_Title": ["Utilization of secondary raw material in geopolymers production"], "Total_Cost": ["EUR 558 000"], "Country": ["Czech Republic", "Czech Republic", "Slovakia", "Czech Republic", "Spain"], "Project_ACR": ["GeoDust"], "Technology_Description": "A lot of cement plants all around Europe are standing before problem of by-pass kiln dust disposal. Nowadays small part of production is added in stabilizing admixture and the rest is disposed of as a waste material. In light of the fact that this material contains approximately 10\u201350 wt. % of KCl, free lime and dicalcium silicate, the possibility of their usage in alkali activated systems is at hand. ", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Czech Republic"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations"], "From": ["2017-01-01"], "Project_ID": ["734833"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA"], "EU_Contribution": ["EUR 244 269"], "Project_Title": ["Re-Empower the BOdy after Tetraplegia."], "Total_Cost": ["EUR 244 269"], "Country": ["Italy"], "Project_ACR": ["REBoT"], "Technology_Description": "REBoT will move its steps towards the understanding of the interrelationships between training-induced brain reorganization and sensorimotor function after cervical spinal cord injury (SCI). The final goal is to promote a \u201crewiring\u201d of the cortex (or supra-spinal circuits) to bypass pathways interrupted by SCI through a progressive adaptation of the rehabilitative intervention.", "To": ["2020-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Chiara Andreoli", "Tel.: +3901071781854", "Fax: +39 010 7170817"], "From": ["2017-12-01"], "Project_ID": ["750464"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Testing Cosmic Inflation and Reheating in the Very Early Universe"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["TESTINF"], "Technology_Description": "The aim of this cosmology proposal is to study the physical conditions that prevailed in the early Universe where a phase of accelerated expansion, \u201cinflation\u201d, took place. I will design a comprehensive pipeline to identify the early Universe models for which the data show the strongest preference. I also propose to use new methods to unveil quantum signals in inflationary observables and use inflation as a quantum laboratory on cosmological scales. I will also extend the range of current and future data sets that can be used to constrain inflation, and derive forecasts for future missions. ", "To": ["2019-06-06, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2017-06-07"], "Project_ID": ["750491"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAET STUTTGART", "UNIVERSITAET STUTTGART"], "EU_Contribution": ["EUR 2 422 543"], "Project_Title": ["Electric field imaging of single molecular charges by a quantum sensor"], "Total_Cost": ["EUR 2 422 543"], "Country": ["Germany", "Germany"], "Project_ACR": ["SMel"], "Technology_Description": "Precision measurements are a key application of quantum technology. They have brought record precision in time measurement or outstanding sensitivity in measuring a whole wealth of quantities. Bringing such measurements to the nanoscale is new. If those quantum sensor function under a variety of environments, including ambient or physiological condition they promise unprecedented application. ", "To": ["2022-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["742610"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["POLITECNICO DI MILANO", "POLITECNICO DI MILANO"], "EU_Contribution": ["EUR 149 375"], "Project_Title": ["A novel instrument to identify chiral molecules for pharmaceutics and bio-chemistry."], "Total_Cost": ["EUR 149 375"], "Country": ["Italy", "Italy"], "Project_ACR": ["CHIMERA"], "Technology_Description": "This proposal aims at bringing to the market a revolutionary device to uniquely identify the chirality of molecules. An object is chiral if it differs from its mirror image, like our left and right hands. Chirality plays an extremely important role in two main fields: (1) Many drugs are chiral and selecting one of the two forms often enables the pharma industry to extend patent franchise, thus increasing profitability, and to improve the quality, safety and efficacy of the drug. (2) Researchers in the chemistry and biophysics labs use chirality as an indication of the 3D structural conformation of proteins and DNA, to study e.g. their secondary structure and stability under external stimuli. Spectrometers for measuring chirality already exist in the market. Many customers in the two aforementioned sectors could be interested in the new product we propose because it presents several advantages, namely a 2-fold reduction of the price, a 4-fold shrinking of the footprint and an increased information content. The ground-breaking concept (under patenting) behind this new spectrometer is to employ an ultra-stable interferometer to measure the chiral spectrum of molecules via a Fourier-transform approach and a heterodyne amplification of the signal. A first working prototype has already been realized and tested. The CHIMERA project has two main goals. (1) We aim at unleashing the innovation potential of the approach, by technically validating two prototypes in a pharmaceutical company and a biochemistry research lab, thus pushing the Technology Readiness Level of the system to the ultimate maturity required to approach the market, corresponding to TRL9. (2) We will design a complete exploitation plan, performing a thorough analysis of the market, developing a financing strategy, benchmarking our instrument against the competitors\u2019 ones, profiling strategic partners and drafting a first version of a Business Plan to decide on the opportunity to found a start-up company.", "To": ["2018-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["754802"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["INSTITUT PASTEUR", "UNIVERSITY OF GLASGOW", "POLO D'INNOVAZIONE DI GENOMICA, GENETICA E BIOLOGIA SCARL", "INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT", "INSTITUT PASTEUR DE NOUVELLE-CALEDONIE", "UNIVERZITA KARLOVA", "CENTRE DE COOPERATION INTERNATIONALE EN RECHERCHE AGRONOMIQUE POUR LEDEVELOPPEMENT - C.I.R.A.D. EPIC", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "INSTITUT DE RECERCA I TECNOLOGIA AGROALIMENTARIES", "EUROPEAN MOLECULAR BIOLOGY LABORATORY", "THE PIRBRIGHT INSTITUTE LBG", "CENTRO AGRICOLTURA E AMBIENTE GIORGIO NICOLI SRL", "TROPIQ HEALTH SCIENCES", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS", "STICHTING KATHOLIEKE UNIVERSITEIT", "Univerzitet u Novom Sadu, Poljoprivredni fakultet Novi Sad", "UNIVERSITAT ZURICH", "Liverpool School of Tropical Medicine", "Institut Pasteur De Dakar", "UNIVERSITE DES SCIENCES DES TECHNIQUES ET DES TECHNOLOGIES DE BAMAKO", "Fondation Health Sciences e-Training", "WAGENINGEN UNIVERSITY", "MINISTERE DE LA SANTE"], "EU_Contribution": ["EUR 9 998 845,25"], "Project_Title": ["Research Infrastructures for the control of vector-borne diseases"], "Total_Cost": ["EUR 9 998 845,25"], "Country": ["France", "United Kingdom", "Italy", "France", "New Caledonia", "Czech Republic", "France", "United Kingdom", "Spain", "Germany", "United Kingdom", "Italy", "Netherlands", "Germany", "Greece", "Netherlands", "Serbia", "Switzerland", "United Kingdom", "Senegal", "Mali", "Switzerland", "Netherlands", "Burkina Faso"], "Project_ACR": ["INFRAVEC2"], "Technology_Description": "The overall objective of the Infravec2 project is to integrate key specialized research facilities necessary for European excellence in insect vector biology, to open the infrastructure for European access, and to develop new vector control measures targeting the greatest threats to human health and animal industries. Infravec2 is an Advanced Community, following a four-year Starting Community lifecycle (FP7 Infravec1). Lack of access to key infrastructures limits European vector research and impedes development of vector control measures. Insect vectors transmit parasitic diseases such as malaria and leishmaniasis, and viral infections such as chikungunya, dengue, Zika, Japanese encephalitis and yellow fever. Vector-borne diseases, which have historically been a problem of tropical countries, now represent a threat for temperate regions of the world including much of Europe. The 24 consortium partners, including 4 commercial companies, hold the major European biosecure insectaries for experimental infection and containment of insect vectors under Containment Level 2 and 3 (CL2/CL3) conditions, other key insect vector facilities, and include front-line field sites in Africa, the Pacific, and the Americas. Infravec2 will implement comparable standards across the secure insectary facilities as a world first, improving exploitation of European vector infrastructures for research and public health, and will develop other innovative methodologies and technologies. Networking activities will assure that the project achieves full impact, producing a step change in European vector biology research and the product pipeline, and consolidating European global leadership in insect vectors. The goal of the Infravec2 project is to build a durable European infrastructure to control insect vector-borne disease, including with power to predict and prevent the inevitable next epidemic outbreak in advance.", "To": ["2021-01-31, ongoing project"], "Meta": [""], "Topic_s": ["INFRAIA-01-2016-2017 - Integrating Activities for Advanced Communities"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Other", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2017-02-01"], "Project_ID": ["731060"], "Call_for_Proposal": ["H2020-INFRAIA-2016-1"]}, -{"Partners": ["THE UNIVERSITY OF NOTTINGHAM"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Studies of Materials and Catalysts by Dynamic Nuclear Polarization Enhanced Solid-state NMR"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["DNPMAT"], "Technology_Description": "Recent innovations in dynamic nuclear polarization (DNP) have transformed the sensitivity of solid-state nuclear magnetic resonance (NMR), resulting in a reduction in experiment time of up to 100,000-fold. This means that previously unobtainable structural details can be quickly obtained by NMR, even for dilute species, such as binding sites in catalysts or functionalizing molecules at surfaces. The objectives of the action are the improved sample preparation protocols, new experimental approaches and proof of principle studies necessary to make DNP-enhanced solid-state NMR the method of choice for the molecular-level characterization of the surfaces of materials. These objectives will be achieved by knowledge exchange between Dr S. Chaudhari, an experienced researcher with a background in developing DNP, and researchers at the University of Nottingham involved in solid-state NMR studies of materials and catalysts. The action is designed to train Dr Chaudhari though high-quality research into applications of DNP-enhanced solid-state NMR to four technologically useful materials: mesocellular silica foams, alumina catalyst supports, surface-coated hydroxyapatite nanoparticles and model catalytic converters. The training will take place at the state-of-the-art UK Facility for DNP-enhanced solid-state NMR operational at the University of Nottingham since November 2015. The Facility\u2019s instrumentation is unique in the UK and is available to external users from both industry and academia, resulting in a vibrant research environment and a ready-made network of collaborators for Dr Chaudhari. In addition, a secondment at a leading sustainable technology company (Johnson Matthey) will ensure that industrial and commercial aspects are fully integrated into the action. The training will transform Dr Chaudhari into a creative and independent scientist working at the frontiers of DNP-enhanced NMR by providing him with the necessary research knowledge and transferable skills.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["747208"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "DANFYSIK AS", "ACADEMISCH ZIEKENHUIS LEIDEN", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.", "TESORO IMAGING SL"], "EU_Contribution": ["EUR 3 216 250"], "Project_Title": ["IN SITU IMAGING OF LIVING TISSUES WITH CELLULAR SPATIAL RESOLUTION"], "Total_Cost": ["EUR 3 216 250"], "Country": ["Spain", "Denmark", "Netherlands", "Germany", "Spain"], "Project_ACR": ["HISTO-MRI"], "Technology_Description": "The main objective of HISTO-MRI project is to develop the technologies that will enable the non-invasive visualization of individual human cells in vivo and in real time, based on a radical new Magnetic Resonance Imaging concept: High Frequency Pulsed MRI. To accomplish this ambitious objective, several new challenging multidisciplinary technologies will have to be developed: 1) new method for the production of magnet coils, based on additive manufacturing technology, in order to stand very high currents at very high frequencies; 2) novel high frequency high voltage pulse power sources, based of semiconductor switches, to feed those magnet coils; and new pulse sequencing and computer algorithms to deal with and analyse the enormous amount of data. Therefore, this project has a foundational character, establishing the basis for a new field of research, pulsed MRI in the high frequency regime, which will radically advance MRI performance to micron resolution.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-01-2016-2017 - FET-Open research and innovation actions"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["737180"], "Call_for_Proposal": ["H2020-FETOPEN-1-2016-2017"]}, -{"Partners": ["COVENTRY UNIVERSITY"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["SOLAR ADSORPTION REFRIGERATOR WITH THIN-LAYER/ENHAMCED ADSORBENT"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SARTEA"], "Technology_Description": "Increased energy costs, the uncertainty of fossil fuel availability, and climate change concerns, have necessitated the quest for renewable energy resources. Solar adsorption systems are quiet, simple to operate, and can last for a long time. However, they have low cooling power density, and subsequently have to be bulky compared to similar solar thermal systems offering the same performance. This can increase their initial costs, especially for small and medium sized systems, thus reducing their uptake. Currently researchers have successfully tackled this issue by, for instance, using more than one adsorbent bed to adopt a continuous cycle, and using forced cooling for the adsorber bed and condenser. These have not resolved the bulk/cost issues, however. This innovative Fellowship will apply a thin layer nano-particles embedded adsorbent, nano-fluid based refrigerants and selectively absorbing solar plate collectors to the system. We will develop a robust simulation model to help with the design process. The system will be partly built using a novel diffusion bonding process that enables dissimilar materials to be joined seamlessly. We will test the adsorption properties of the novel adsorbent materials and apply them to the refrigerator. We aim to deliver a solar adsorption refrigerator that employs nano-technology and novel manufacturing methods, meets the performance improvements currently achievable but not with the bulk and complexity. We expect scholars and industry to also apply the technology demonstrated to several other uses, and for them to be more accessible to the general public. The Fellow has all the necessary skills and experience required (including chemical adsorption, thermodynamics, heat & mass transfer) while the host lab has all the infrastructure and experience of hosting researchers. The project is also timely as it fits into the EU Energy policy (ESTPP Vision 2030).", "To": ["2018-03-31, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-04-01"], "Project_ID": ["661515"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 200 194,80"], "Project_Title": ["Wealth, Virtue and Social Justice in Contemporary Tibet"], "Total_Cost": ["EUR 200 194,80"], "Country": ["Denmark"], "Project_ACR": ["VIRTUE"], "Technology_Description": "This project examines the relationship between Buddhism and ideas about wealth, virtue and social justice in contemporary Tibet. The objectives are: a) to reveal central moral assumptions about value and the social good in a \u2018Buddhist\u2019 society experiencing rapid development, rising consumption levels and growing inequalities; and b) to use these findings to engage with wider theoretical debates about value and exchange, commodity and gift, and religion and economy. The relationship between Buddhism and economy remains an underdeveloped research area \u2013 indeed my project coincides with a drive at the University of Copenhagen\u2019s Centre for Contemporary Buddhist Studies to address this gap. Although often imagined to be antithetical to contemporary consumer society, Buddhism has historically been intertwined with the economy and monasteries were dominant political and economic institutions in Tibet. In recent years increasing wealth has been flowing to Tibetan monasteries and monks in a hitherto unexamined variety of forms and modes, some of which have been the subject of moral reflection and critique. This upsurge in patronage has paralleled rising income and consumption levels, but also increasing inequalities, resulting from processes of Chinese state-led development. Utilising a unique and extensive body of ethnographic materials that I have collected during long-term fieldwork in north-eastern Tibet, I will document and analyse a variety of cases of patronage of Tibetan monastic Buddhism in their local contexts. Drawing for inspiration on the \u2018moral turn\u2019 in anthropology, my aim is to identify and analyse points of ethical reflection, tension and debate at the interface between Buddhism and economy. My hypothesis is that this will reveal underlying ideas about value and the social good; and that this will in turn help us to revisit and reassess both our understanding of Buddhism and theories of exchange, value and consumption dominated by economistic approaches.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["747673"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["High-throughput characterization of host promiscuity for precisely designed synthetic viral capsid"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["Hi-SynVir"], "Technology_Description": "Traditional geographic ranges of insect pests are altered by globalization and climate change, resulting in emerging threats for natural ecosystems, agriculture and human health. It is urgent to improve our ability to swiftly develop targeted solutions to contain such threats, while minimizing unintended side effects on the environment.", "To": ["2017-06-30, Grant Agreement terminated |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2015-07-01"], "Project_ID": ["660212"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE UNIVERSITY OF WARWICK"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["In situ stress analysis of lithium-ion battery cell"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["LIB STRESS"], "Technology_Description": "Lithium-ion batteries (LIB) are found in many applications such as consumer electronics, electric vehicles and airplanes. However, despite of the high safety standards being imposed, there have been many reported accidents as well as recalls by some manufacturers. Most accidents can be sourced to runaway reactions, which could happen if the LIBs are overheated or overcharged. Thermal runaway can cause rapid temperature rise in the LIB, resulting in excessive thermal stress in the electrodes and the separator, a permeable membrane placed between the anode and cathode. Such mechanical degradation can cause the fading of battery capacity, and in extreme cases result in cell rupture, releasing of flammable gases, fire and explosions. ", "To": ["2020-07-29, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-07-30"], "Project_ID": ["749512"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["VALSTYBINIS MOKSLINIU TYRIMU INSTITUTAS FIZINIU IR TECHNOLOGIJOS MOKSLU CENTRAS"], "EU_Contribution": ["EUR 114 432,15"], "Project_Title": ["Energy losses in nitride light-emitting diodes"], "Total_Cost": ["EUR 114 432,15"], "Country": ["Lithuania"], "Project_ACR": ["NITRIDE-SRH"], "Technology_Description": "Light-emitting diodes (LEDs) are the future of lighting for general-purpose and industrial applications because of their potentially superior efficiencies. Group-III nitrides are the principal materials used to manufacture blue and green LEDs. However, they are still rather inefficient, despite a lot of research efforts. Increasing the efficiency and reducing the cost of LEDs is currently the question of paramount importance.", "To": ["2017-01-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Lithuania"], "Activity": ["Research Organisations"], "From": ["2015-05-01"], "Project_ID": ["657054"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["LUXEMBOURG INSTITUTE OF SCIENCE AND TECHNOLOGY"], "EU_Contribution": ["EUR 172 800"], "Project_Title": ["Gestures in Tangible User Interfaces"], "Total_Cost": ["EUR 172 800"], "Country": ["Luxembourg"], "Project_ACR": ["GETUI"], "Technology_Description": "GETUI investigates through user studies the use of gestures in interaction with Tangible User Interfaces (TUIs) in the context of technology-based assessment (TBA) of collaborative and complex problem solving skills. Collaborative problem solving is defined as the capacity to recognise the perspective of other people in a group, participate, contribute knowledge, recognise the need for contributions and build knowledge and understanding as member on a collaborative setting (Ras et al. 2013). Most of the research in TBA of collaborative problem solving skills dealt with the improvement of assessment of traditional skills. However, the focus should be on the so-called 21st Century skills: CPS, creativity, critical thinking, learning to learn, decision-making. Ras et al. (2013) state that for many challenges in TBA, ICT are the solution to assess 21st Century skills, but also the problem, as scientific knowledge about how assessment models need to be adapted as well as practical knowledge about how to create more authentic problem situations with future assessment tools are lacking. Until now there is no TUI that has been systematically used and evaluated in the context of TBA. Moreover, in TBA, gestures on TUIs have not been yet explored. Thus not only is the research of TUI as an assessment construct a new research field, but also the dimension of gestures makes GETUI an innovative and timely project. This interdisciplenary research will not only fill the gap of scientific knowledge, but will also have an impact at a European level creating new instruments for assessing 21st Century skills based on capturing behavioural indices of human-computer and human-human interactions in collaborative TBA situations.", "To": ["2017-10-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["Luxembourg"], "Activity": ["Research Organisations"], "From": ["2015-11-01"], "Project_ID": ["654477"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITEIT LEIDEN", "UNIVERSITEIT LEIDEN", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV"], "EU_Contribution": ["EUR 1 499 950"], "Project_Title": ["Plant foods in human evolution: Factors affecting the harvest of nutrients from the floral environment"], "Total_Cost": ["EUR 1 499 950"], "Country": ["Netherlands", "Netherlands", "Germany"], "Project_ACR": ["HARVEST"], "Technology_Description": "Plant foods comprise the majority of most human diets, yet the potential importance of these foods in human evolution is often overlooked. Using a behavioral ecology framework, the HARVEST project explores fundamental questions: Why did hominins choose to eat certain plants? What were their foraging goals? We will focus on two objectives: 1) Reconstructing the diets of fossil hominins and 2) Exploring the costs and benefits of plant foods.", "To": ["2022-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719"], "From": ["2017-02-01"], "Project_ID": ["677576"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["NATURAL ENVIRONMENT RESEARCH COUNCIL"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Peering through the East Antarctic Ice Sheet to reveal geology, crustal architecture and tectonic influences on ice sheet dynamics"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["REVEAL"], "Technology_Description": "Although East Antarctica is regarded as a keystone in the Rodinia and Gondwana supercontinents and is a pivotal component of the global climatic system it remains the least known continent on Earth. With REVEAL we aim to unveil the crustal structure, tectonic architecture and evolution of several major frontier regions in East Antarctica. The project will also address large-scale geological controls on bedrock topography, subglacial hydrology and ice sheet dynamics. Our models and interpretations of potential field data will enable us test several hypotheses regarding the effects of collision, accretion and rifting on East Antarctica. This has significant implications for comprehending the impact of supercontinental assembly and break up on the structure and evolution of East Antarctica. Using state of the art three dimensional modelling, we will obtain an enhanced understanding of intraplate mountain building in the enigmatic Gamburtsev Subglacial Mountains region. This is highly significant, as these mountains were critical for East Antarctic Ice Sheet development. The enhanced knowledge of subglacial geology that will derive from our analyses of the Recovery Frontier and Wilkes Land will facilitate new assessments of the influence of geological boundary conditions on the dynamics and the stability of these potentially more vulnerable marine-based parts of the East Antarctic Ice Sheet. The REVEAL project has a strong international dimension and will deliver several high-profile publications and dissemination activities. It will provide unique and timely training and career development opportunities for the experienced researcher.", "To": ["2017-05-17, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations"], "From": ["2015-05-18"], "Project_ID": ["657187"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["HELSINGIN YLIOPISTO"], "EU_Contribution": ["EUR 191 325,60"], "Project_Title": ["Biodiversity drivers on islands and continents"], "Total_Cost": ["EUR 191 325,60"], "Country": ["Finland"], "Project_ACR": ["BIODIV ISLAND-CONT"], "Technology_Description": "Why do some regions encompass higher number of species? Which are the main drivers of biodiversity in different biogeographical areas and ecosystems? Many efforts have been made to decipher the main factors that play a key role in the patterns and processes that generate biodiversity and contribute to the structuring of communities at different spatial scales. Through a multidisciplinary approach, this project aims to shed light into the biogeographical and evolutionary processes that generate biodiversity, using multiple island and continent datasets to compare diversity drivers between model systems where distinct processes have shaped the current species composition. The feasibility of BIODIV ISLAND-CONT is supported by the extensive database provided by four different European funded projects, offering an invaluable tool to study the differences in community assembly of islands vs. continents. The project will be hosted by two high-quality European institutions: FMNH-UH in Finland and IPNA-CSIC in Spain, enhancing the reciprocal transfer of knowledge among different European partners. Overall, the goals proposed in this project will allow testing general macroevolutionary hypotheses of broad interest to the scientific community.", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["706482"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["TECHNISCHE UNIVERSITEIT DELFT"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["Bell Experiment on Quantum Optomechanical Microresonators"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["BEQOM"], "Technology_Description": "Experimental demonstration of superposition states of massive systems, often referred to as Schr\u00f6dinger cat states, has been an exciting research line of several fields in quantum physics. There have been many impressive experiments with a variety of different systems over the past years and research along these lines is still highly popular.", "To": ["2019-07-16, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-17"], "Project_ID": ["740475"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI MILANO"], "EU_Contribution": ["EUR 180 277,20"], "Project_Title": ["Direct reprogramming for HD Disease Modelling"], "Total_Cost": ["EUR 180 277,20"], "Country": ["Italy"], "Project_ACR": ["DISMOD-HD"], "Technology_Description": "Huntington\u2019s disease (HD) is a rare and devastating autosomal dominantly inherited disorder caused by the amplification of the CAG codon in the huntingtin gene. The clinical symptoms of HD are chorea and motor incoordination as well as psychiatric symptoms. To date no cure has been found to alter the progression of the striatal atrophy due to the dramatic loss of GABAergic medium spiny neurons (MSNs) which eventually leads to death. Over the past years increasing knowledge around the function of huntingtin (HTT) has allowed the identification of number pathogenic mechanisms, however the specific processes whereby the mutated HTT leads to degeneration and their temporal evolution remains unknown. We believe it is of vital importance to develop disease-relevant human cell models from clinically characterized HD subjects in which to address questions related to pathogenic mechanisms and their dependence on the CAG repeats. For this reason the aim of the proposed project is to generate induced medium spiny neurons (iMSNs) from healthy or HD-diseased fibroblasts in order to generate a reliable disease modelling tool. The applicant will optimize an existing protocol for the generation of iMSNs from direct conversion of fibroblasts published by Victor et al (2014) to obtain healthy iMSNs in the laboratory of prof. Elena Cattaneo at the University of Milan. In a second step she will perform direct in vitro reprogramming of human fibroblasts derived from well characterized patients affected with HD exhibiting different degrees of CAG repeat expansion into induced HD-derived MSNs (HD-iMSNs). Finally, the newly generated HD-iMSNs will be analyzed, and their characteristics compared to those of the healthy iMSNs, in order to assess their appropriatness as a disease modelling tool to investigate the pathophysiology and pathogenesis of HD.", "To": ["2019-05-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-15"], "Project_ID": ["753077"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI MILANO"], "EU_Contribution": ["EUR 180 277,20"], "Project_Title": ["Breaking frontiers in plant reproduction: understanding the roles of AGPs and epigenetics regulating male-female crosstalk towards fertilization"], "Total_Cost": ["EUR 180 277,20"], "Country": ["Italy"], "Project_ACR": ["EpiAGPs"], "Technology_Description": "\u201cBy 2050 the Earth will need to feed two billion more people. How can we achieve that without overwhelming the planet?\u201d The question, raised back in 2009, demands quick action. Human life depends on plants, which feeds us, our livestock or fulfils our biofuel needs. Thus to feed this growing population, it will be necessary to double agricultural yields without increasing the amount of arable land. A fine knowledge of the fundamental molecular processes that finely regulate plant reproduction, will allow increasing crop productivity and high quality seed production in a sustainable manner by agricultural engineering, safeguarding the increase of arable land usage.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["753328"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["MEDICAL RESEARCH COUNCIL"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["The role of OTULIN and Met1-linked ubiquitin in immune signaling and host defense in vivo"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["OTULINVIVO"], "Technology_Description": "The immune system is essential for host defense against infections. Methionine1-linked \u2018linear\u2019 ubiquitin chains (Met1-Ub) have emerged as a crucial activator of NF-\u03baB transcription factors, which are vital to immune responses. Recent findings suggest that defects in Met1-Ub signaling in humans can lead to severe immune dysfunction and cancer. Met1-Ub is generated by the linear ubiquitin chain assembly complex (LUBAC). Yet, how LUBAC and Met1-Ub signaling are regulated remains elusive. We recently discovered OTULIN, the only deubiquitinase known to specifically disassemble Met1-Ub. OTULIN antagonizes LUBAC and restricts Met1-Ub and NF-\u03baB signaling in cell culture; however, the role of OTULIN and Met1-Ub in immune signaling and host defense in vivo is largely unknown. We have established novel mouse strains with cell type-specific deletion of OTULIN. I will use these mice to explore the in vivo function of OTULIN and Met1-Ub in the innate and adaptive immune responses, and to identify OTULIN substrates in primary cells using state-of-the-art mass spectrometry-based proteomics. I will study OTULIN\u2019s role in immune homeostasis, in response to bacterial infection, and in mounting type-1 and type-2 adaptive immune responses by state-of-the-art methods of immunological analyses including comprehensive multiplex analyses of cytokines. Met1-Ub regulates the acute phase cytokines TNF and IL-6 and may thus control the development of type-1 versus type-2 immune responses. Hence, I will test OTULIN\u2019s role in models of asthma, a disorder characterized by an imbalance between type-1 and type-2 responses. Subsequently, I will analyze immune signaling pathways in primary cells using mass spectrometry-based proteomics to identify OTULIN substrates in specific cell types. This will greatly deepen our understanding of the physiological role of OTULIN and Met1-Ub in the immune response and may provide important insight into human immunological disorders and rationales to treat these.", "To": ["2017-03-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations"], "From": ["2015-04-01"], "Project_ID": ["654019"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION"], "EU_Contribution": ["EUR 1 416 000"], "Project_Title": ["SupercompuTing And Related applicationS Fellows Program"], "Total_Cost": ["EUR 2 832 000"], "Country": ["Spain"], "Project_ACR": ["STARS"], "Technology_Description": "The BSC STARS (SupercompuTing And Related applicationS) International Research Fellows program aims at fostering the training of highly skilled post-doc in all fields of High Performance Computing and related applications, specifically in Earth Science and Meteorology, in Life Sciences, Genomics and Personalised Medicine and in Computational Engineering and Physics and Computational Societies, providing them with all the necessary tools for developing their potentials, deepening their skills and knowledge in a stimulating, international and interdisciplinary environment, offering them intersectorial secondments with private industry or non-academic Research centers, in order to boost their career perspectives as successful independent researchers.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2016 - Co-funding of regional, national and international programmes"], "Funding_scheme": ["MSCA-COFUND-FP - Fellowship programmes"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["754433"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2016"]}, -{"Partners": ["INSTYTUT MATEMATYCZNY POLSKIEJ AKADEMII NAUK.", "UNIWERSYTET WARSZAWSKI", "UNIWERSYTET LODZKI", "UNIVERSITY OF GLASGOW", "THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN", "KOBENHAVNS UNIVERSITET", "WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER", "VRIJE UNIVERSITEIT BRUSSEL", "SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI DI TRIESTE"], "EU_Contribution": ["EUR 288 000"], "Project_Title": ["New Geometry of Quantum Dynamics"], "Total_Cost": ["EUR 288 000"], "Country": ["Poland", "Poland", "Poland", "United Kingdom", "United Kingdom", "Denmark", "Germany", "Belgium", "Italy"], "Project_ACR": ["QUANTUM DYNAMICS"], "Technology_Description": "The Project aims to make significant advances to the field of noncommutative geometry by developing new methods through substantial interaction within sub-fields of noncommutative geometry and two other areas of pure mathematics. The main focus will be to determine the topological non-triviality of new types of quantum fibrations. Also, we aim to construct quantum metric geometries of crossed products and graph algebras relating the Lipschitz-norm and Dirac-operator approaches. The Project will combine various areas, which although interacting on the fundamental level, have had their concrete and usable connections mostly unexplored. ", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Poland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["691246"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["HASKOLI ISLANDS", "HASKOLI ISLANDS"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Developing Novel and Optimal Additive Solutions for Red Blood Cells"], "Total_Cost": ["EUR 150 000"], "Country": ["Iceland", "Iceland"], "Project_ACR": ["DENOVO-RBC"], "Technology_Description": "The research conducted in SYSTEM_US (ERC Advanced Grant #232816) has led to the discovery of valuable biomarkers for the quality of red blood cells (RBCs) in standard blood bank storage conditions. Using a combination of systems biology and metabolomics, this discovery will lead to the development of novel RBC storage technologies including additive solutions and diagnostics. These technologies will become valuable assets in the form of intellectual property to large transfusion medicine companies and will save thousands of lives over the coming decades. This proposal covers the needs to fully define the market and NPV of the developing technology, fully define the regulatory and clinical path of product approval, file for patents to protect the intellectual property, conduct necessary validation experiments, and continue to develop relations with industry contacts.", "To": ["2016-08-31, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2014 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Iceland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-03-01"], "Project_ID": ["641093"], "Call_for_Proposal": ["ERC-2014-PoC"]}, -{"Partners": ["UNIVERSIDAD DE CORDOBA"], "EU_Contribution": ["EUR 257 191,20"], "Project_Title": ["Understanding Non-Photochemical Quenching Regulation in a Dynamic Environment."], "Total_Cost": ["EUR 257 191,20"], "Country": ["Spain"], "Project_ACR": ["UNREDE"], "Technology_Description": "Life on Earth relies on photosynthesis that converts water and carbon dioxide into organic molecules using absorbed light by chlorophylls bound to light harvesting complexes (LHC). During evolution, LHC have maximized the capability to capture light energy, allowing organisms to grow even in very low light environments. However, during nutrient deprivation or under high light conditions, when light absorption exceeds the capacity for carbon dioxide fixation, the excess absorbed energy can elicit the generation of reactive oxygen species that cause severe oxidative damage. Photosynthetic organisms have developed mechanisms of non-photochemical quenching (NPQ) that alleviate this photo-oxidative stress in the timescale of seconds to minutes. This NPQ is critical to protect the integrity of the photosynthetic apparatus, allowing the organisms to survive in a dynamic light and nutrient environment. In algae, LHCSR (LHC Stress Related) proteins catalyze NPQ, but their specific role and regulation are poorly understood. For this project, I will use the model organism Chlamydomonas reinhardtii in which two LHCSR proteins have been identified. My main goals will be (1) to characterize components involved in NPQ under conditions experienced in nature, where light intensities vary and nutrient conditions (C, N and S) are suboptimal, and (2) to explore regulatory circuits and signaling molecules that impact NPQ. The experimental approaches involve characterization of novel mutant strains unable to properly trigger NPQ, transcriptomic analysis to elucidate the effect of NPQ deficit on global gene expression and pharmacological approaches to explore the impact of different signaling molecules in NPQ. Understanding NPQ is essential to predict how photosynthetic organisms will behave with changes in atmospheric dioxide fixation levels, temperature and nutrient availability, but will also impact strategies for improving photosynthetic efficiency and tolerance to harsh conditions.", "To": ["2021-01-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-15"], "Project_ID": ["751039"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Roma, Gypsies and Travellers' social in/exclusion in European urban camps"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["CAMP-BIVALENCE"], "Technology_Description": "The project aims to analyse the role of Civil Society Organisations (CSOs) in Roma, Gypsies and Travellers\u2019 (RGTs) in/exclusion in European urban camps. Triangulating individual semi-structured interviews, oral histories, archival research, and interpretative policy analysis, the interdisciplinary project combines Sociological, Socio-Anthropological and Socio-Historical approaches, contemplating two UK and two Italian superdiverse urban contexts as case studies. It contributes to three research streams: housing exclusion; RGT policy, and camps as socio-spatial configurations, and inaugurates a new interdisciplinary research field on Urban Camps. Dr Sigona, who will act as the Supervisor, is a leading scholar in migration and Roma research in Europe; his expertise is particularly complementary with Dr Picker research skills and knowledge coming from ten years of Sociological field-based research on Roma spatial segregation in five European countries. Due to the excellent quality of infrastructure, scholarly research and staff, the School of Social Policy and the Institute for Research into Superdiversity at the University of Birmingham are the most appropriate academic environment for Dr Picker to become, after the Fellowship, a leading social science scholar in the European Research Area.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["661646"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["INSTYTUT CHEMII FIZYCZNEJ POLSKIEJ AKADEMII NAUK", "UNIVERSITAET REGENSBURG", "TEL AVIV UNIVERSITY"], "EU_Contribution": ["EUR 688 500"], "Project_Title": ["Metallocomplexes of macrocyclic compounds for photonic devices"], "Total_Cost": ["EUR 688 500"], "Country": ["Poland", "Germany", "Israel"], "Project_ACR": ["METCOPH"], "Technology_Description": "The key objective of the METCOPH multidisciplinary project is to intensify and consolidate cooperation between several research groups from member states and third countries on topics within the field of fundamental interdisciplinary science. The project combines the basic ideas of organic chemistry, solid state physics, photochemistry and spectroscopy of metallocomplexes of macrocyclic compounds (MMC) for applications in quantum information processing, sensing, switching and amplification.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Poland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-01-01"], "Project_ID": ["645628"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["QUEEN MARY UNIVERSITY OF LONDON"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["The Internet of Musical Things - An ecosystem of interoperable devices connecting performers and audiences"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["IoMUT"], "Technology_Description": "This project aims at designing, developing, and validating new interfaces for technologically-mediated interaction between performers and audiences in order to achieve novel forms of musical expression and foster audience engagement in live performing arts. Current systems for networked music performances that allow performers to collaboratively create music over a network), and for participatory live music performance that enable audiences to actively engage in the music creation process, are limited both from the technological and artistic perspectives. To progress the state-of-the-art, we propose to extend the concepts of the Internet of Things to the musical domain leading to a subfield that we coin as the Internet of Musical Things (IoMUT). IoMUT refers to the network of physical objects (Musical Things) dedicated to the production and fruition of multimodal musical content. This project will implement the IoMUT by creating Musical Things in the form of new musical instruments and new wearable devices, and by delivering a technological infrastructure that allows for their bidirectional wireless communication, both locally and remotely. Such an infrastructure will enable an ecosystem of interoperable devices connecting performers as well as performers and audiences to support new performer-performer and audience-performers interactions, not possible beforehand. The project will define and implement some use cases demonstrating the proposed IoMUT and evaluate them. This approach aspires to effect a step-change in the design of interfaces for musical expression, resulting in a potentially high economic impact on the whole music industry. The project also contributes to the fundamental understanding of the mechanisms underlying music perception and music performance in interactive and multimodal contexts.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["749561"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["DEUTSCHES INSTITUT FUR INTERNATIONALE PADAGOGISCHE FORSCHUNG"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Processes and Outcomes of Educational Evaluation from a Cross-Cultural Perspective"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["POEECCP"], "Technology_Description": "The full complexity of educational evaluation at various levels (i.e., system, school, classroom, and student) in different countries has hardly been recognized. It constitutes a tremendous barrier to consolidate theories on evaluation, and for countries to draw on successful experience and implement targeted educational policies for better quality and effectiveness. Important barriers include the insufficient methodology to soundly compare multiple countries and a cultural insensitive approach to unfolding evaluation processes and outcomes. This project aims to provide a comprehensive framework for the dynamics of evaluation with a solid cross-cultural research methodology. Using self-report data in 70 countries/economies in the 2015 Programme for International Student Assessment (PISA), this project delineates the pathways in processes and outcomes of educational evaluation in 70 educational systems by integrating policies at system level, practices in schools and classrooms, and student assessment outcomes with demonstrated comparability of data. Study 1 has a methodological focus to analyze scalable measures and their cross-cultural comparability. It tests whether self-report multiple-item measures from school principals, teachers, and students across countries reach approximate measurement invariance to ensure proper comparisons. Study 2 tests the effects of accountability policy, country affluence at country-level, and various evaluation practices including the feedback mechanisms at school and teacher levels, and the cross-level interactions on a broad range of student outcomes such as achievement, motivation, wellbeing, and test anxiety. This project contributes to theory building on educational evaluation from a cross-cultural perspective and identify effective measures for more targeted educational interventions.", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["748788"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["REGionalism And INstututional dynamics in the EU"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["REGAIN"], "Technology_Description": "The research project aims to investigate the formation of non-standard regions and the activation of multi-level governance practices induced by EU-led territorial cooperation instruments. It identifies four types of non-standard regions (micro, cross-border, off-shore and macro) that correspond to 4 EU instruments (CLLD, EGTC, maritime spatial planning, and Macro-regional strategy). They constitute a programmatic domain in which the EU is advocating a new regionalism agenda, which is based on the construction of new territorialised polities engaged in regional development and planning actions beyond formal administrative boundaries, from municipal to national ones. These new regional polities present an extensive variety of socio-institutional dynamics, committed to thematic or political objectives, and policy delivery channels. The scope of the project is to evaluate whether the tailoring of these regional polities contribute to address more appropriately socio-ecological regions, to activate cultural-cognitive understanding of new functional territories, to conceive more efficient spatial planning and development strategies. The project investigates one case-study region per each instrument, with a primary attention to two areas: a new micro-region and a cross-border region, which will be evaluated in relation to their overlapping/interaction with off-shore and macro-regions. Moreover, the fellowship poses the basis for a cutting-edge research program that explores the socio-cultural, political and institutional construction of these new territorialised polities; investigates their socio-institutional efficiency; makes explicit the characteristics of a renewed EU-led regionalism agenda; and clarifies the limits and the opportunities that a regionalism agenda on non-standard region has in addressing the challenges of contemporary Europe and its regional dynamics.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["749899"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Transmission of Financial Shocks:A systemic Input-Output GVAR approach"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["Shocks Transmission"], "Technology_Description": "Over the past years, the economic and financial systems have become increasingly globalized and vulnerable with important implications for risk management by commercial banks and other institutions. However, despite the fact that sophisticated models for quantifying credit risk have been developed, everyday practice has shown that risk, due to its inherent role in the economic system, is affected by both: (i) macroeconomic factors and (ii) financial factors. Hence, it would be extremely beneficial to generate scenario analyses, real-time simulations and forecasts based on a core set of variables.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["749161"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE PARIS-SUD"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Novel 3D nano-antennas for optoelectronic applications in the mid-infrared"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["NANO-MIR"], "Technology_Description": "This research proposal aims at implementing novel functionalities for mid-infrared optoelectronic devices and to study novel physical phenomena, enabled by a new class of 3D plasmonic nanostructures that provide access to electromagnetic field confinements.", "To": ["2020-03-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-04-01"], "Project_ID": ["748071"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["REGION HOVEDSTADEN"], "EU_Contribution": ["EUR 200 194,80"], "Project_Title": ["Statistical Modelling for relating multimodal neuroimaging to clinical outcomes in order to predict patient response to depression therapy."], "Total_Cost": ["EUR 200 194,80"], "Country": ["Denmark"], "Project_ACR": ["NEUROMODEL"], "Technology_Description": "Every year, 1 out of 15 Europeans suffer from major depression (MDD) and MDD is the third cause of Disability-adjusted life-years. Today, the available treatments are clearly insufficient; only about 50% of MDD patients respond to drug intervention. We here posit that identification of biomarkers that can predict treatment response is needed to adapt a personalized medicine approach, and most likely this will involve not a single outcome but a combination of multimodal brain imaging outcomes, psychological, genetic, and environmental data. The complexity of such data requires a complex statistical model that currently does not exist. Thus, my aim is to develop a new flexible statistical method that can take into account heterogeneous types of data. More specifically, I will develop a fully flexible Latent Variable Model (LVM) that can deal with high dimensional measurements (e.g. images), non-Gaussian variables, and non-linear relationships. I will apply this flexible LVM on existing data from depressed and healthy individuals and later expand the application to predict treatment outcomes. The latter data are currently acquired and includes a cohort of MDD patients treated with a selective serotonin reuptake inhibitor (SSRI), followed in a longitudinal design. The chosen host institution is perfectly situated to this project, as they have an established unique database including, e.g., functional Magnetic Resonance Imaging (fMRI), high resolution Positron Emission Tomography (PET), and neuropsychological test outcomes. This research project uniquely combines advanced statistical modelling of rich data sets with the ultimate aim to establish individualized depression therapy. Moreover, it forms a foundation for a more general approach to integrate brain neurobiology in terms of imaging outcomes with other patient-specific data.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-06-01"], "Project_ID": ["746850"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE PARIS-SUD"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Chaos-based information processing using spintronic nano-oscillators"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["CHAOSPIN"], "Technology_Description": "ChaoSpin is a frontier research project at the interface between nanomagnetism, spintronics, and nonlinear dynamics. It is motivated by the premise that the rich behaviour of nonlinear systems, in particular chaos, can be leveraged for alternative computing paradigms. The primary objective is to establish the utility and feasibility of the nanocontact vortex oscillator, a nanoscale spintronic device, as a universal building block for chaos-based information processing by demonstrating key technological functionalities, such as random number generation and communication using symbolic dynamics. The underlying idea is that the complexity required for computation and possible cognitive functions can be generated within a single system, without the need of a complex array of interconnected subsystems.", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["751344"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich"], "EU_Contribution": ["EUR 175 419,60"], "Project_Title": ["Topological states with Spin-Dependent potentials for ultracold lithium"], "Total_Cost": ["EUR 175 419,60"], "Country": ["Switzerland"], "Project_ACR": ["TopSpiD"], "Technology_Description": "The recent understanding of the topological properties of matter has led to the search for the experimental production and control of topological excitations such as Majorana fermions. They appear at the boundary between a topological superconductor and a normal metal and have intriguing properties such as non-abelian exchange statistics and insensitivity to decoherence. Their production would give an invaluable insight on the properties of topological phases of matter as well as paving the way towards fault-tolerant quantum computing. The aim of this action is to create them in an ultracold atom set-up which is a ideal platform to engineer interesting Hamiltonians.", "To": ["2020-06-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-07-01"], "Project_ID": ["746150"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FUNDACIO INSTITUT DE CIENCIES FOTONIQUES"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Optical valley Hall effect in gapped graphene for infrared and terahertz light photodetection"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["VHPC"], "Technology_Description": "Modern information processing is based on the degrees of freedom (DOF) of electrons, which are known as charge and spin. Manipulating DOF of electrons is the core function of information-processing unit such as transistor and photodetector. Finding and manipulating new DOF for electrons may open up possibility for next-generation information processing, such as quantum computing. Recently, a new DOF of electrons\u2014valley pseudospin\u2014was found in two dimensional (2D) hexagonal lattices, whose band structures manifest a pair of valleys at the corner of the hexagonal Brillouin zone (labeled as K and -K valley), giving rise to a valley DOF that is in close analogy to electron spin. As 2D hexagonal crystal, graphene, with ultrahigh carrier mobility and ultrafast optoelectronic signal processing ability, has great potential as carrier of valley DOF and intriguing prospect for both fundamental research and practical application of valleytronics. Therefore manipulating valley pseudospin of electrons in graphene would greatly advance the study of valleytronics. This proposal presents the first experimental study of Berry optoelectronics in gapped graphene, in particular extremely strong Valley Hall effects and Valley Hall dynamics. The implementation includes three sections. The first is to break inversion symmetry of graphene crystal by fabricating graphene/boron nitride heterostructure and dual-gate bilayer graphene device. This symmetry breaking allows the Bloch electrons in K and -K valleys to experience valley-contrasted orbital magnetic moments and Berry curvatures, which result in valley-dependent optical selection rule and valley Hall effect. This supplies us paradigm for infrared and terahertz photodetection for section two. In section three, we explore the dynamics of confining charge carriers in a specified valley, by measuring the time-resolved behaviors.", "To": ["2019-08-21, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-08-22"], "Project_ID": ["747927"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF LEEDS"], "EU_Contribution": ["EUR 269 857,80"], "Project_Title": ["Voltage Control of Chiral Spin Structures"], "Total_Cost": ["EUR 269 857,80"], "Country": ["United Kingdom"], "Project_ACR": ["V-ChiralSpin"], "Technology_Description": "This project will develop a new way to manipulate chiral spin structures such as skyrmions using voltages. Building on the expertise of the fellow in voltage control of magnetism in multiferroic heterostructures, this project uses the unique Spin-Polarised Low Energy Electron Microscope (SPLEEM, in Berkeley) to characterize chiral spin structures in tailored multiferroic heterostructures. By studying (in Leeds) the effects of voltage control on current-driven skyrmion motion in these heterostructures, V-ChiralSpin aims to establish a new, technologically relevant, research area.", "To": ["2021-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["750147"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Unwanted catches of trawl fisheries: ecosystem effects and advances to an integratedmanagement approach in the Mediterranean"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["FishMan"], "Technology_Description": "There is an urgent need to address the environmental effects of fishing in order to maintain healthy marine ecosystems that provide the services societies want and need. This problem is addressed in the new Common Fisheries Policy by encouraging the adoption of an Ecosystem Approach to Fisheries, including as a matter of priority the reduction of unwanted catches. In line with this policy, the project aims to address the ecosystem effects of commercial trawling, including the unwanted catches problem, and generate knowledge that will contribute to the adoption of EAF. The project is structured in several inter-disciplinar activities, starting with gathering existing information on fishing effort, catches, benthic species and habitats from trawling grounds in the NW Mediterranean. The information will be analysed to assess the vulnerability of by-catch species to trawling, and the Good Environmental Status of benthic ecosystems. The novelty of the research approach will be increased by the adoption of a social-ecological framework. Interviews with the principal stakeholders will aim to assess their perception on the services provided by ecosystems from trawling grounds, and identify priority areas for fisheries and for conservation. The vulnerability, GES and ecosystem services valorisation will be used to propose scenarios of alternative fishing strategies that minimise the negative effects on ecosystems, while taking into account societal priorities. Then, size-spectra mathematical models will be explored to assess the ecosystem response to the different scenarios, aiming to identify the optimal management alternatives. The project structure will follow the principles of a participatory approach, by taking into account fishermen\u2019 perceptions on potential management alternatives, which will allow exploring real-world scenarios.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-06-01"], "Project_ID": ["743545"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KATHOLIEKE UNIVERSITEIT LEUVEN", "DANMARKS TEKNISKE UNIVERSITET", "UNIVERSITA DEGLI STUDI DI PADOVA", "KARLSRUHER INSTITUT FUER TECHNOLOGIE", "TECHNISCHE UNIVERSITEIT DELFT", "THE UNIVERSITY OF NOTTINGHAM", "LAYERWISE", "NUOVO PIGNONE SRL", "ALICONA IMAGING GMBH", "LEGO SYSTEM AS"], "EU_Contribution": ["EUR 3 944 925,36"], "Project_Title": ["Precision Additive Metal Manufacturing"], "Total_Cost": ["EUR 3 944 925,36"], "Country": ["Belgium", "Denmark", "Italy", "Germany", "Netherlands", "United Kingdom", "Belgium", "Italy", "Austria", "Denmark"], "Project_ACR": ["PAM^2"], "Technology_Description": "Additive Manufacturing (AM) is a fast\u2212growing sector with the ability to evoke a revolution in manufacturing due to its almost unlimited design freedom and its capability to produce personalised parts locally and with efficient material use. AM companies however still face technological challenges such as limited precision due to shrinkage and build\u2212in stresses and limited process stability and robustness. Moreover often post\u2212processing is needed due to the high roughness and remaining porosity. In addition qualified, trained personnel is hard to find. This ITN project will address both the technological and people challenges.", "To": ["2020-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-12-01"], "Project_ID": ["721383"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["UNIVERSITAETSKLINIKUM HAMBURG-EPPENDORF", "UNIVERSITAETSKLINIKUM HAMBURG-EPPENDORF"], "EU_Contribution": ["EUR 149 825"], "Project_Title": ["Advanced platform for profiling of therapeutic targets and functional analysis of circulating tumour cells in cancer patients"], "Total_Cost": ["EUR 149 825"], "Country": ["Germany", "Germany"], "Project_ACR": ["CTCapture_2.0"], "Technology_Description": "As an alternative to invasive needle biopsies, the analysis of CTCs released by metastatic lesions into the blood has been recently introduced by the PI as \u201cliquid biopsy\u201d. The molecular analysis of CTCs before and during treatment could supply a real-time status of the landscape of metastatic tumor cell clones in an individual cancer patient. CTCs might reveal representative information on metastatic cells located at different sites because the blood represents a pool of tumor cells potentially released by all lesions in the cancer patients. Moreover, blood samples can be taken sequentially during the course of the disease and therefore allow a real-time assessment of the molecular evolution of the disease with important implications for decision making on cancer therapies. However, despite the obvious potential of CTCs as biomarker, current CTC capture assays require sophisticated, expensive and complex assay systems, which is the most important bottleneck for a more widespread use of CTCs as liquid biopsy. The assay development in the ERC PoC Grant CAPTURE-CTC (end: 11/2016) and the successful research on improved methods for molecular characterization of CTCs in the Advanced Investigator Grant DISSECT (end: 07/2016) of the PI has allowed to develop a novel improved platform for CTC detection. To implement our chip into future clinical decision making, we will now focus on the clinical validation of the chip platform including the development of SOPs as basis for kits for expression of therapeutic targets and resistance mechanisms in CTCs. Moreover, the establishment of transient CTC cultures from chip-isolated tumor cells will foster drug testing in individual cancer patients. In conclusion, the CTCapture_2.0 project will be an important prerequisite for successful future commercialization of a novel liquid biopsy assay.", "To": ["2018-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["754453"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["FUNDACIO INSTITUT DE CIENCIES FOTONIQUES"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Environmental friendly narrow band-gap colloidal nanocrystals for optoelectronic devices"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["NAROBAND"], "Technology_Description": "In recent years a widespread investigation of semiconductor materials and its use in optoelectronic devices has taken place. Despite the vast variety of semiconductor materials, solution processable semiconductor nanocrystals (NC\u2019s) take lead thanks to their excellent optoelectronic properties (tunable band-gap, high PLQY and optical stability) while they become more and more appealing for their low production cost. Although, a variety of semiconductor NC\u2019s have been synthesized for application in the visible spectral region, only few examples exist with tunability in mid and near-IR, and most notable high toxicity mercury and lead based NCs. On the other hand, nowadays we experience a burst of emerging near and mid-IR technologies (e.g. solar cells, detectors, night cameras) which are moving towards the use of environmentally friendly IR emitting materials for large scale production. Therefore, NAROBAND aims to exploit the synthesis and the functionalization of low-toxic narrow-band gap Ag2SxSey NC\u2019s via both chemical and physical routes towards the fabrication of environmental friendly, low cost solar cell devices. The project focus on achieving full control of the bandgap (1.2eV\u20130.4eV) via quantum confinement and stoichiometry allowing to decouple nanocrystals size and surface effects from bandgap, leading to a better control of the optoelectronic properties. Moreover, throughout careful surface characterization and functionalization NAROBAND aims to suppression of the trap state density, enhancing the carrier mobility and manipulating the energy levels of the valence and conduction band of the NC\u2019s. These material advancements will pave the way towards, firstly, the fabrication of high efficient IR solar cell devices and later on the realization of tandem solar cell by using the conventional Si technology to harvest the high energy electromagnetic radiation of the sun, while the aforementioned solar cell device will collect the, so far wasted, IR radiation.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-06-01"], "Project_ID": ["750600"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 276 107,40"], "Project_Title": ["Resilience, Mindfulness and Medication Safety with Electronic Systems"], "Total_Cost": ["EUR 276 107,40"], "Country": ["United Kingdom"], "Project_ACR": ["MindSElS"], "Technology_Description": "Medications are one of the most common healthcare interventions and one with great risk of adverse events and serious harm to patients. Medications incidents in hospitals are frequent and a serious concern. Electronic medicine management systems (EMMS) implemented in hospital are known to reduce some safety risks but also introduce new ones. A way to prevent harm to patients from the use of medication is through organising for collective mindfulness (alertness to risks) and through learning from everyday resilience. EMMS introduced in sociotechnical contexts of hospital care may affect collective mindfulness and resilience, in ways that are context (or nation) specific, as countries differ in structures, processes, and legislation.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["740131"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF CYPRUS", "UNIVERSITY OF CYPRUS", "PHOEBE RESEARCH AND INNOVATION LTD"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Intelligent Building Automation Diagnostics"], "Total_Cost": ["EUR 150 000"], "Country": ["Cyprus", "Cyprus", "Cyprus"], "Project_ACR": ["Domognostics"], "Technology_Description": "The emergence of networked cyber-physical systems, in which sensor/actuator networks are integrated with software algorithms, facilitates the development of advanced Building Management Systems (BMS) aimed at enhancing energy efficiency in buildings, which accounts for 40% of the energy consumption in the EU. When a fault arises in some of the components, or an unexpected event occurs in the building, this may lead to a serious degradation in performance or, even worse, to situations that would endanger people\u2019s lives. Studies estimate that 20% of the energy consumed in commercial buildings for heating, ventilation, air conditioning, lighting and water heating can be attributed to various faults. Therefore, there is a market need for an intelligent building automation diagnostic system which integrates with existing BMS to facilitate continuous and effective monitoring of the buildings.", "To": ["2018-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Cyprus"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-05-01"], "Project_ID": ["755134"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["POLITECNICO DI MILANO", "POLITECNICO DI MILANO", "CONSIGLIO NAZIONALE DELLE RICERCHE"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Nichoid: nanoengineered three-dimensional substrate for stem cell expansion"], "Total_Cost": ["EUR 150 000"], "Country": ["Italy", "Italy", "Italy"], "Project_ACR": ["NICHOIDS"], "Technology_Description": "\"Mesenchymal stem cells (MSCs) raise a great interest for regenerative medicine for many clinical applications such as orthopaedic, plastic and reconstructive surgery, within autoimmune or degenerative disease treatment and as immune-suppressive agents in organ transplantation. In stem cell therapy, cells are injected in the patient after an extensive in vitro manipulation aimed at obtaining a sufficient cell number able to guarantee the therapeutic effect. Currently, stem cell \"manufacturing\" implies the use of \u201cfeeder\u201d cells and additives from animal sources, hampering the clinical use mainly for safety reasons. In the context of an ERC Consolidator grant (ERC-CoG) that I currently lead, I introduced a novel ground-breaking concept for an easy to use, repeatable, cost-effective, and safe substrate for stem cell expansion, called the \u201cnichoid\u201d substrate, capable of avoiding feeder cells and dangerous additives. The substrate is polymerized with a laser in a biocompatible resin using a frontier nano-fabrication technology called \u201ctwo-photon laser polymerization\u201d (2PP). To explore the possibility of an economic exploitation of this invention covered by an Italian Patent submitted in September 2015 and already extended as PCT, the goal of this PoC is to perform a technical and commercial feasibility to move the method developed in the PI\u2019s laboratory during the ERC grant to the market. In particular, I plan to speed up the maturity level of the technology further developing the production process of individual nichoids (fabrication up-scaling by at least a factor of 10, allowing to cover a culture surface of 5 squared cm in five hours), setting of an actionable IPR strategy (including a market assessment), identification of the suitable exploitation strategy for valorising the patent/know how (licensing). The nichoid could drastically reduce down to few years the time to market of stem cell products that is currently 20 years.\"", "To": ["2018-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2017-06-01"], "Project_ID": ["754467"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["UNIVERSITAT DES SAARLANDES", "UNIVERSITAT DES SAARLANDES"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Mining Sandboxes for Automatic App Protection"], "Total_Cost": ["EUR 150 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["BOXMATE"], "Technology_Description": "Today\u2019s industry is more vulnerable to cyberattacks than ever. The biggest threat comes from advanced persistent threats that targets the sensitive data of a specific company. Such a threat may come along as an innocuous app that starts its malicious behavior only when the mobile logs into the corporate network.", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Germany"], "Activity": ["Peter Druschel", "Tel.: +4968193039100", "Fax: +4968193036029", "Higher or Secondary Education Establishments", "Corinna Hahn", "Tel.: +49 681 95 92 3362", "Fax: +49 681 95 92 3370", "Higher or Secondary Education Establishments", "Corinna Hahn", "Tel.: +49 681 95 92 3362", "Fax: +49 681 95 92 3370"], "From": ["2017-09-01"], "Project_ID": ["737566"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["HELSINGIN YLIOPISTO", "HELSINGIN YLIOPISTO"], "EU_Contribution": ["EUR 1 342 132,50"], "Project_Title": ["High-density QCD matter from first principles"], "Total_Cost": ["EUR 1 342 132,50"], "Country": ["Finland", "Finland"], "Project_ACR": ["DenseMatter"], "Technology_Description": "Predicting the collective properties of strongly interacting matter at the highest densities reached within the present-day Universe is one of the most prominent challenges in modern nuclear theory. It is motivated by the desire to map out the complicated phase diagram of the theory, and perhaps even more importantly by the mystery surrounding the inner structure of neutron stars. The task is, however, severely complicated by the notorious Sign Problem of lattice QCD, due to which no nonperturbative first principles methods are available for tackling it.", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["725369"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["KOZEP-EUROPAI EGYETEM", "KOZEP-EUROPAI EGYETEM"], "EU_Contribution": ["EUR 1 833 214"], "Project_Title": ["Political and Business Networks"], "Total_Cost": ["EUR 1 833 214"], "Country": ["Hungary", "Hungary"], "Project_ACR": ["POLBUSNETWORKS"], "Technology_Description": "I explore the role of networks involving firms---networks between firms and politicians, and networks between firms and firms--for economic outcomes. I focus on two broad questions. (1) What are the determinants and implications of political favor networks? Although political favoritism affects allocations in many countries, its mechanisms are not well understood. I develop a new model based on the idea of trust embedded in favor networks, and test in Hungarian data the model's implications about how political centralization shapes favoritism. I also quantify the welfare cost of misallocation created by favoritism. My results help understand how political institutions shape economic outcomes. (2) What is the impact of supply chain networks on firm performance? Inputs from suppliers account for the majority of firm sales, yet we know little about the contribution of suppliers to firm performance. I use a field experiment in China to measure the causal effect of suppliers and the underlying mechanisms. I then use observational data from Hungary to quantify the contribution of differences in suppliers to differences in firm performance. The results help understand how supply chains and their misallocation shape firm and aggregate productivity. My approach to both of these questions emphasizes the role of trust embedded in firm networks and how these trust-based networks create misallocation of resources. A key component of this research is the development of original datasets. Beyond documenting and explaining facts, I also hope to obtain policy implications on reducing favoritism and improving firm performance in developing countries.", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Hungary"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["724501"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE"], "EU_Contribution": ["EUR 149 648"], "Project_Title": ["Fast Proof Reading and Correction of Complex Delineations"], "Total_Cost": ["EUR 149 648"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["FastProof"], "Technology_Description": "This project aims at turning the novel approach to automated delineation of complex curvilinear structures we have developed under ERC funding into industrial-grade software that can be commercialized. Our primary goal will therefore be to transform our research software into user-friendly plugins with well-defined APIs that can be bundled with widely used commercial software platforms. ", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["727227"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI TORINO", "UNIVERSITA DEGLI STUDI DI TORINO"], "EU_Contribution": ["EUR 1 793 421"], "Project_Title": ["The functional interaction of EGFR and beta-catenin signalling in colorectal cancer: Genetics, mechanisms, and therapeutic potential."], "Total_Cost": ["EUR 1 793 421"], "Country": ["Italy", "Italy"], "Project_ACR": ["BEAT"], "Technology_Description": "Monoclonal antibodies against the EGF receptor (EGFR) provide substantive benefit to colorectal cancer (CRC) patients. However, no genetic lesions that robustly predict \u2018addiction\u2019 to the EGFR pathway have been yet identified. Further, even in tumours that regress after EGFR blockade, subsets of drug-tolerant cells often linger and foster \u2018minimal residual disease\u2019 (MRD), which portends tumour relapse. ", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["724748"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSIDAD POMPEU FABRA", "UNIVERSIDAD POMPEU FABRA"], "EU_Contribution": ["EUR 1 999 813"], "Project_Title": ["Electronic AXONs: wireless microstimulators based on electronic rectification of epidermically applied currents"], "Total_Cost": ["EUR 1 999 813"], "Country": ["Spain", "Spain"], "Project_ACR": ["eAXON"], "Technology_Description": "To build interfaces between the electronic domain and the human nervous system is one of the most demanding challenges of nowadays engineering. Fascinating developments have already been performed such as visual cortical implants for the blind and cochlear implants for the deaf. Yet implantation of most electrical stimulation systems requires complex surgeries which hamper their use for the development of so-called electroceuticals. More importantly, previously developed systems based on central stimulation units are not adequate for applications in which a large number of sites must be individually stimulated over large and mobile body parts, thus hindering neuroprosthetic solutions for patients suffering paralysis due to spinal cord injury or other neurological disorders. A solution to these challenges could consist in developing addressable single-channel wireless microstimulators which could be implanted with simple procedures such as injection. And, indeed, such solution was proposed and tried in the past. However, previous attempts did not achieve satisfactory success because the developed implants were stiff and too large. Further miniaturization was prevented because of the use of inductive coupling and batteries as energy sources. Here I propose to explore an innovative method for performing electrical stimulation in which the implanted microstimulators will operate as rectifiers of bursts of innocuous high frequency current supplied through skin electrodes shaped as garments. This approach has the potential to reduce the diameter of the implants to one-fifth the diameter of current microstimulators and, more significantly, to allow that most of the implants\u2019 volume consists of materials whose density and flexibility match those of neighbouring living tissues for minimizing invasiveness. In fact, implants based on the proposed method will look like short pieces of flexible thread.", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["724244"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["TECHNISCHE UNIVERSITEIT DELFT", "TECHNISCHE UNIVERSITEIT DELFT"], "EU_Contribution": ["EUR 1 955 112,50"], "Project_Title": ["Flows Unveiled: Multimodal Measurement in Opaque Two-Phase Flows"], "Total_Cost": ["EUR 1 955 112,50"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["OpaqueFlows"], "Technology_Description": "Dispersed multiphase flows are encountered in nearly every process in nature and industry; examples include sediment in rivers, catalysts in reactors and blood flow. Despite their relevance, it is currently difficult to accurately and efficiently model these flows. The opacity of the flows, even at moderate volume fractions, renders the common optical flow measurement tools useless. As a result, very little high-quality data is currently available to develop (numerical) models.", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["725183"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["TECHNISCHE UNIVERSITAT DARMSTADT", "TECHNISCHE UNIVERSITAT DARMSTADT"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Photonic Terahertz Signal Analyzers"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["Pho-T-Lyze"], "Technology_Description": "Spectrum analysis and vector network analysis are enabling technologies for component development throughout the microwave and millimeter wave band. Due to the lack of affordable electronics for frequencies above 100 GHz, vector network analyzers (VNAs) have to use frequency extenders to reach into the THz frequency band (100 GHz-10 THz). The bandwidth of frequency extended electronic systems is restricted to about 50%. Several extender setups have to be used for larger spans, requiring realignment and tedious recalibration. Further, extenders become increasingly expensive the higher the THz frequency and are, therefore, barley used. Electronic spectrum analyzers face similar problems as VNAs. Only a few examples of highly expensive photonic, pulsed frequency comb-based systems have been demonstrated. Affordable, large bandwidth commercial THz metrology tools are missing so far. ", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["713780"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["THE UNIVERSITY OF EDINBURGH", "THE UNIVERSITY OF EDINBURGH"], "EU_Contribution": ["EUR 1 999 784,99"], "Project_Title": ["Molecular control of DNA replication timing in mammalian cells"], "Total_Cost": ["EUR 1 999 784,99"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["RepTime"], "Technology_Description": "DNA replication is an essential process ensuring the transmission of genetic information and is highly regulated. Specifically, the DNA replication-timing program ensures that the sites of initiation of DNA replication, termed origins, are not all activated simultaneously but follow a cell-type specific schedule. This pathway is conserved throughout eukaryotic evolution, however its molecular control and biological role are not fully understood. In this proposal I aim to understand key aspects of replication-timing program by employing a combination of advanced mouse genetics, genomics, cell biology and proteomics. Currently one of the major limitations in the mammalian DNA replication field is the elusive identity of origins. I aim to comprehensively map origins in a variety of mouse cells/tissues and relate the regulation of origin firing to the control of gene expression and three-dimensional nuclear architecture. I have discovered that Rif1 controls replication timing and links it to nuclear three-dimensional organization. I have also revealed the existence of a novel Rif1-independent pathway that controls the timing of a significant fraction of the late-replicating genome, identified by constitutive association with a key nuclear architecture component, Lamin B1. Here, I propose complementary approaches to understand the molecular mechanism by which Rif1 coordinates replication timing and nuclear organization as well as the molecular underpinnings of the novel pathway instructing late-replication in Lamin B1-associated regions. Finally, my goal is to understand the in vivo biological role of the replication-timing program. Our preliminary data identify mammalian X inactivation as a process where replication timing may play a fundamental part. My ultimate objective is to contribute to the realization of a comprehensive understanding of nuclear function, integrating the co-regulation of DNA replication with gene expression, epigenetic inheritance and DNA repair.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["726130"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSIDAD PABLO DE OLAVIDE"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Food in the Spanish and British Caribbean in the Nineteenth Century: Encounters, Exchanges, Identities"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["Imperial Recipes"], "Technology_Description": "This research project aims to compare the British and Spanish empires in the nineteenth-century Caribbean. More specifically, it focuses on the discourse on food in the British and Spanish colonies. This project stems from my doctoral research. My aim is both to find a connection between the ways in which food and diet were perceived and discussed in the British and Spanish Caribbean colonies and to evaluate the differences in the discourse on food in the two empires, with the objective of analyzing colonial identities and imperial ideology in the Caribbean through the lens of food. My focus on food and diet sheds light on how encounters, negotiations, appropriations, rejections and interactions of culinary practices are more than just a matter of human nutrition but rather concern fundamental issues as the construction of identities, asymmetries of power, agency of the subaltern and mutual influences. The basic assumption of this project is therefore an analysis of the relationship between food, identity and power.", "To": ["2017-05-31, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-06-01"], "Project_ID": ["659541"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITEIT ANTWERPEN", "UNIVERSITEIT ANTWERPEN", "UNIVERSITAETSKLINIKUM BONN", "SAN DIEGO STATE UNIVERSITY FOUNDATION"], "EU_Contribution": ["EUR 2 417 000"], "Project_Title": ["Nodding Syndrome: a trans-disciplinary approach to identify the cause and decrease the incidence of river epilepsy"], "Total_Cost": ["EUR 2 417 000"], "Country": ["Belgium", "Belgium", "Germany", "United States"], "Project_ACR": ["NSETHIO"], "Technology_Description": "Nodding syndrome (NS) is a neurological, incurable syndrome, currently affecting mainly children between 5 and 15 years of age in South Sudan, Uganda and Tanzania. Since 1950, when NS was first described, its cause has remained a mystery. NS is characterized by head-nodding (an atonic form of epilepsy), often followed by clonic - tonic seizures, developmental retardation and faltering growth. In the affected regions, NS is a major public health problem associated with severe socio-economic consequences. After exploratory missions to South Sudan, Uganda and the Democratic Republic of the Congo (DRC), we gathered epidemiological evidence that supports the hypothesis that NS is a disease caused by a pathogen transmitted by blackflies, the vectors that transmit the parasitic worm that causes onchocerciasis. This pathogen could be an unknown neurotropic virus or another pathogen that is transmitted either independently or as a symbiont of the worm. We postulate that this pathogen is able to cause typical NS, but also other forms of epidemic epilepsy. We hypothesise that the same disease is also endemic in other onchocerciasis hyper-endemic regions e.g. in the Mbam valley, Cameroon and the Orientale Province, DRC (where it is referred to as \u201criver epilepsy\u201d). In this project we aim to investigate our hypotheses in South Sudan, Uganda, Tanzania, Cameroon and the DRC with a trans-disciplinary approach including clinical-epidemiological, post-mortem, eco-entomological, and metagenomic studies. We will study the effect of vector control methods and ivermectin distribution on the incidence of river epilepsy. So far a multi-country study on NS was never done and nearly all previous studies were cross-sectional, carried out during short country visits. With this long term research plan we hope to finally discover the cause of NS and detect effective control strategies to decrease the incidence of epilepsy in onchocerciasis endemic areas.", "To": ["2020-09-30, ongoing project |"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other"], "From": ["2015-10-01"], "Project_ID": ["671055"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["UNIVERSIDAD PABLO DE OLAVIDE", "UNIVERSIDAD PABLO DE OLAVIDE", "CURT-ENGELHORN ZENTRUM ARCHAOMETRIEGGMBH-CEZA", "FUNDACION UNIVERSIDAD DEL NORTE", "UNIVERSITA DEGLI STUDI DI PAVIA"], "EU_Contribution": ["EUR 1 998 875"], "Project_Title": ["An ARTery of EMPIRE. Conquest, Commerce, Crisis, Culture and the Panamanian Junction (1513-1671)"], "Total_Cost": ["EUR 1 998 875"], "Country": ["Spain", "Spain", "Germany", "Colombia", "Italy"], "Project_ACR": ["ArtEmpire"], "Technology_Description": "European incursions onto the narrow isthmian pass that divided and connected the Atlantic and Pacific oceans made it a strategic node of the Spanish Empire and a crucial site for early modern globalization. On the front lines of the convergence of four continents, Old Panama offers an unusual opportunity for examining the diverse, often asymmetrical impacts of cultural and commercial contacts. The role of Italian, Portuguese, British, Dutch, and French interests in the area, as well as an influx of African slaves and Asian merchandise, have left a unique material legacy that requires an integrated, interdisciplinary approach to its varied sources. Bones, teeth and artifacts on this artery of Empire offer the possibility of new insights into the cultural and biological impact of early globalization. They also invite an interdisciplinary approach to different groups\u2019 tactics for survival, including possible dietary changes, and the pursuit of profit. Such strategies may have led the diverse peoples inhabiting this junction, from indigenous allies to African and Asian bandits to European corsairs, to develop and to favor local production and Pacific trade networks at the expense of commerce with the metropolis.", "To": ["2020-12-31, ongoing project |"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["648535"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["CHALMERS TEKNISKA HOEGSKOLA AB"], "EU_Contribution": ["EUR 185 857,20"], "Project_Title": ["Geometry and Computational Anatomy"], "Total_Cost": ["EUR 185 857,20"], "Country": ["Sweden"], "Project_ACR": ["GEOCA"], "Technology_Description": "The past decades have brought fascinating technological improvements of medical imaging techniques. This rapid development is accompanied by a growing need for computer based algorithms to align and extract markers from medical images. The days of heuristically engineered computer algorithms are, however, over; competitive, state-of-the-art medical imaging software must be based on rigorous mathematics to ensure accuracy, efficiency, and stability.", "To": ["2017-02-28, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-03-01"], "Project_ID": ["661482"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET", "KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 289 928"], "Project_Title": ["Support to the Vice-Presidents of the ERC Scientific Council 2017"], "Total_Cost": ["EUR 289 928"], "Country": ["Denmark", "Denmark"], "Project_ACR": ["ERC VP CSA"], "Technology_Description": "The European Research Council (ERC) provides a competitive platform for investigator-driven frontier research at the European level. It is led by a Scientific Council (ScC) consisting of 21 eminent scientists and their President, and it is this council that independently establishes and oversees the ERC's scientific management and the implementation of its Work Programme. This project aims to support the ERC Vice-Presidents, who act on an honorary basis, in the efficient and timely achievement of the ScC's goals in 2017. ", "To": ["2017-12-31, closed project"], "Meta": [""], "Topic_s": ["IBA-ERC-VPRES-SUP-17 - Support to the Vice-Chairs"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["764466"], "Call_for_Proposal": ["H2020-IBA-ERC-VPRES-SUP-17"]}, -{"Partners": ["NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU", "NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Cognitive Geometry: Deciphering neural concept spaces and engineering knowledge to empower smart brains in a smart society"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Norway", "Norway"], "Project_ACR": ["GEOCOG"], "Technology_Description": "Through smart technology, we are overwhelmed with new information. Does this unlimited access to knowledge make us smarter? One of the key challenges for modern societies is to understand how the brain assembles\u00a0our rich inventory of knowledge. Here, I will test the hypothesis that newly acquired knowledge is represented in the hippocampal formation in neural concept spaces, which are based on the coding principles and representational structures of the neural machinery involved in spatial navigation. The key idea is that the brain\u2019s navigation system provides the building blocks of a neural metric for knowledge. In this groundbreaking cognitive neuroscience framework, I will bridge and integrate principles from Nobel Prize awarded neurophysiology and concepts from cognitive science and philosophy. Partly building on my ERC-StG project in which I discovered the core neural mechanisms underlying reconfiguration, integration and scaling of memory networks, the aim of my proposal is two-fold: 1. I seek to decipher neural concept spaces and unravel the neural codes of a cognitive geometry for knowledge and its deformations. 2. I will provide a proof-of-principle framework for next-generation neurocognitive technology and neural user models for cognitive enhancement to edit memories and engineer knowledge. Novel \u2018Wikipedia\u2019 learning tasks will be combined with state-of-the-art pattern analyses of space-resolved fMRI and time-resolved MEG to map and quantify representational structures. I will further develop AI-inspired analyses and closed loop brain-computer interfaces to perturb and edit neural concept space. The integrative mission of my program, from cells to systems-level involvement in cognition and to technology, opens up the exciting possibility to lay the ground for redefining cognitive neuroscience of knowledge by unravelling the fundamental neural principles of a cognitive topography and to make critical translations to empower smart brains in a smart society.", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["724836"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["FREIE UNIVERSITAET BERLIN"], "EU_Contribution": ["EUR 119 595,60"], "Project_Title": ["The Bible and the Law in Carolingian Europe: Scriptural Exegesis and Royal Legislation from Charlemagne to Charles the Bald (ca. AD 780-880)"], "Total_Cost": ["EUR 119 595,60"], "Country": ["Germany"], "Project_ACR": ["BIBLACE"], "Technology_Description": "In what ways did the Bible shape the formation of political communities in early medieval Europe? This project studies the impact of biblical models on royal legislation in the Carolingian period (ca. AD 780-880). It proposes a new approach to the study of the intersection between religion and politics in a formative period of European history, during which crucial institutional and conceptual resources for the development of political and religious community, statehood and law were created. Under the Carolingian rulers from Charlemagne onwards, we can observe a steady increase of biblical quotations in legal texts issued by the ruler or by assemblies of lay and clerical advisers (so-called royal \u2018capitularies\u2019 and conciliar decrees). Biblical prescriptions and prohibitions were either directly integrated into legal norms or used to justify the establishment or modification of norms. To understand this convergence between biblical law and royal legislation, the rich material of Carolingian biblical exegesis is of crucial importance, since it provides access to the concepts and interpretative traditions associated with specific biblical texts in the minds of contemporaries. Authors and readers of exegetical commentaries were often at the same time advisers to kings and important political decision makers, and also involved in the drafting of legislative texts. The project thus proposes a comparative study of legal and exegetical texts and of their dynamic relationship. It has a twofold objective: first, to analyse the concrete impact of biblical models upon Carolingian society, and the ways in which they were used to (re)define its legal and moral framework; second, to understand the \u2018social life\u2019 of Carolingian biblical commentaries, both as a spiritual and intellectual endeavour and as a social and political practice.", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["655748"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["CONSIGLIO NAZIONALE DELLE RICERCHE", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "UNIVERSITA DELLA CALABRIA", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSITE LIBRE DE BRUXELLES", "UNIVERSITY OF STRATHCLYDE", "Centre for Process Innovation Limited", "GVS S.P.A.", "FUJIFILM DIOSYNTH BIOTECHNOLOGIES UK LIMITED"], "EU_Contribution": ["EUR 3 533 813,75"], "Project_Title": ["Revolutionising Downstream Processing of Monoclonal Antibodies by Continuous Template-Assisted Membrane Crystallization"], "Total_Cost": ["EUR 3 533 813,75"], "Country": ["Italy", "United Kingdom", "Italy", "France", "Belgium", "United Kingdom", "United Kingdom", "Italy", "United Kingdom"], "Project_ACR": ["AMECRYS"], "Technology_Description": "Separation and purification of biopharmaceuticals is today one of the most time and cost intense Downstream Processing (DSP) operations in the manufacture of commercial products. Separation and purification of proteins is usually achieved chromatographically, with all of its disadvantages including high buffer requirements, large footprint, reuse and storage of resin studies as well as costs. Traditional DSP based on batch chromatography contribute ca. 66% of the total production cost of anti-cancer monoclonal antibodies (mAbs). Largely contributing to this is the cost of chromatography media; for instance, the cost of 1 L of protein A resin with binding capacity of 20-70 g mAb is about 25000 Eur. By a visionary and ambitious combination of the emerging Continuous Manufacturing Paradigm with innovative Membrane Crystallization Technology and the selective nanotemplate-recognitions directly from the fermentation broth, the AMECRYS Network aims to develop a new Continuous Template-Assisted Membrane Crystallizer in order to revolutionize the DSP platform for mAbs production, thus achieving unprecedented purification and manufacturing efficiencies. Major research challenges will include: i) the synthesis of 3D-nanotemplates with specific molecular recognition ability towards mAbs from complex solutions; ii) the development of tailored macroporous fluoropolymer membranes for advanced control of selective heterogeneous nucleation; iii) the design of multilevel microfluidic devices for high-throughput mAb crystallization screening in a wide range of conditions under continuous flow (\u201cpharma-on-a-chip\u201d concept); iv) technology scale-up to a L-scale continuous prototype designed with recognition of QS/GMP compliance for biopharmaceuticals. The replacement of chromatography with a single membrane-crystallization unit will lead to >60% CapEx and O&M costs decrease, 30-fold footprint reduction and high-purity solid formulation of mAbs with preserved biological activity.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-1-2014 - FET-Open research projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-10-01"], "Project_ID": ["712965"], "Call_for_Proposal": ["H2020-FETOPEN-2014-2015-RIA"]}, -{"Partners": ["UNIVERSITEIT ANTWERPEN"], "EU_Contribution": ["EUR 172 800"], "Project_Title": ["Physiological and environmental controls of water and ozone fluxes in a short rotation poplar plantation: from leaf to tree to ecosystem scale."], "Total_Cost": ["EUR 172 800"], "Country": ["Belgium"], "Project_ACR": ["PHYSIO-POP"], "Technology_Description": "One of the consequences of global climate changes is the altered global water availability. Among the greenhouse gases (GHGs) causing global climate changes, carbon dioxide (CO2) has received most attention. Over the last decennia the impact of rising CO2 concentrations on crops has been widely studied. The study of tropospheric ozone (O3) and its consequences on crops has not been as extensive, although O3 is a widespread and damaging air pollutant in industrialized countries. The PHYSIO-POP project fits within the search for renewable (bio-)energies, in particular the production of woody biomass energy. The project will examine the water consumption and the sensitivity to O3 pollution of a short rotation poplar plantation with fast-growing poplars (Populus spp.) for biomass production.", "To": ["2017-08-31, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["657123"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["FREIE UNIVERSITAET BERLIN"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Will this fire burn out? The topos of lovers' separation in the Italian Renaissance"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["FUDOGE"], "Technology_Description": "The project aims to achieve the first in-depth study on the lyrical topos of lovers\u2019 separation (i.e. when a lover has to go away and therefore leaves her/his beloved for some time) in the Italian Renaissance. The study is meant to improve our knowledge about: 1) the different ways to read and re-use the tradition in the Renaissance; 2) the role of Petrarch as an authority in Renaissance love literature, also in comparison to other models; 3) the interaction between lyrics and love treatises, as well as between literature and philosophy in the conception and representation of love in the Renaissance. For such a goal, Dr. Favaro will analyze the topos of lovers\u2019 separation in Renaissance lyrics and love treatises, paying attention to their mutual interaction, as well as to the relationship with the previous literary tradition and with philosophical sources (especially Neoplatonism). He will also achieve the commented editions of two little-known Renaissance dialogues entirely devoted to the subject of lovers\u2019 separation.", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["653443"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["iRhom2 in neuroinflammation and pathogenesis of Alzheimer\u2019s Disease"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["iRhom2 in AD"], "Technology_Description": "Alzheimer\u2019s disease (AD) is the most common form of dementia in the elderly, a syndrome characterized by loss of memory and cognitive decline. AD has a dramatic socio-economical impact that is foreseen to worsen in the near future unless a cure is found. The pathology is triggered by the accumulation of A\u03b2 oligomers that begins a cascade culminating with the formation of neurofibrillary tangles within the neuron and cell death. Neuroinflammation is emerging to play a key role in this process and it has been associated with the progression of the disease. ", "To": ["2017-11-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-12-01"], "Project_ID": ["658061"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["FREIE UNIVERSITAET BERLIN", "VIB"], "EU_Contribution": ["EUR 171 684"], "Project_Title": ["Molecular mechanisms of neuronal connectivity - the synaptic code for variability and stereotypy"], "Total_Cost": ["EUR 171 684"], "Country": ["Germany", "Belgium"], "Project_ACR": ["Molmechindividuality"], "Technology_Description": "Behaviour emerges from an interplay of various brain regions and billions of neurons forming a network. The brain acquires its organization by a series of developmental events. The correct wiring of the brain is crucially important for all brain functions. Nevertheless, the brain is both stereotyped and variable across individuals. Currently only a subset of genes have been identified that shape specificity in connectivity and it is highly elusive what promotes variability in synaptic connectivity and whether this is behaviourally relevant. To work on these questions I have chosen the Drosophila olfactory system, which is well-defined both on the levels of circuitry and behaviour and as such well-suited to answer these question. Furthermore, from the perspective of circuitry, it is particularly appropriate as it is comprised of both deterministic and non-deterministic synaptic connectivity. In a first step to tackle the question, I will perform a screen to identify genes shaping deterministic and non-deterministic neural connectivity. In parallel, I will investigate olfactory behavioural variability in the fly and correlate this to circuitry variations on the morphological, synaptic and electrophysiological level. After identifying genes that are important for connectivity and correlating circuit to behavioural variability, I aim to modify circuit variability to alter behaviour.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2016-09-01"], "Project_ID": ["656824"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITY OF LEEDS"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Model theory of finite and pseudofinite structures"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["MODFIN"], "Technology_Description": "The project is in model theory (mathematical logic), which concerns the expressibility in logical languages of properties of mathematical structures (e.g. graphs, groups, rings). Model theory aims to identify borders between `tame' and `wild' objects in mathematics, and to pin down abstract notions of independence and dimension and understand the geometry of `definable sets' in a structure, often with wide-ranging applications. This project focusses on classes of finite structures (e.g. the class of all finite fields), and on the `ultraproduct' construction which converts a class of finite structures to an infinite `pseudofinite' structure' which inherits properties of the class and is amenable to model-theoretic methods, with applications for the finite structures. Key objectives include:", "To": ["2018-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["656422"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["FREIE UNIVERSITAET BERLIN"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["The Rhyme: Theory and History of the rhyme in Italian and European literature"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["RTHRIEL"], "Technology_Description": "The objective of the present research proposal is to outline a general theory of the rhyme which might fully explain the meaning of such a device, filling a very significant gap in metrics and literary theory. The research has already started with a forthcoming article and a 3,5 months DAAD scholarship at the Freie Univestit\u00e4t Berlin: the present research proposal aims at developing it into a monograph. The already written chapters concern the general theory (1-Figurative function of the rhyme; 2-Outlines of a semiotics of the rhyme) and the intertextual implications of the rhyme. The new chapters to be written from scratch will concern: 1) the outlines of a general history of the rhyme (still lacking), from its origins up to the 20th Century; 2) the analysis, from the outlined theoretical perspective, of the main traditional rhyming structures (terzina, ottava, sonetto, canzone etc.) and their significance to the text; 3) an account of the partial revival of rhyme in present-day literature, in the attempt to answer the question if rhyme is still possible today and to what extent; 4) the relation of rhyme and psychoanalysis; 5) the question \u2013 hardy ever dealt with \u2013 of the relation of rhyme and rhyme patterns to music; 6) a survey of the use of rhyme in non-literary text, such as nursery rhymes, pop music lyrics, advertisements, to check the validity and the limits of the theory beyond literature and also to address a wider audience; 7) the outline of a \u201cphilosophy of rhyme\u201d, examining the aesthetical conception implied by such a device; 8) an analysis of the use of the word \u201crhyme\u201d when it appears in rhyme producing a metadiscourse in metrics and poetics. Besides the monograph, an important result will be the development of a refined rhyme-search software for digitized text corpora. The research results will be disseminated also through the web (wikies, websites, high-profile literary blogs) and through participation in workshops and international conferences.", "To": ["2018-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-11-01"], "Project_ID": ["699899"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITE DE RENNES I"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Selecting non-crop flowering plants for enhancing natural enemies of crop pests in agro ecosystems under climate change perspective"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["FLORALWOOD"], "Technology_Description": "Throughout Europe, the expansion of modern, chemical-intensive agriculture is regarded as the principal cause of widespread declines in abundance and diversity beneficial arthropods. Conservation of natural enemies in agricultural landscapes is considered the most ecologically sustainable method for biological control of agricultural pests. An ecological relevant hypothesis is that higher plant diversity, through addition of plant species able to supply accessible food and/or shelters at different seasons of the year, can increase natural enemies' fitness. Based on existing insights in insect\u2013plant interactions, specific floral seed mixtures (to be placed in field margins or as ground cover vegetation) can be developed which target specific visiting biocontrol agents. However, the particular mechanisms involved and potential for practical use in farm management remain unclear. In this project I propose to consider the insect community level, including pests and their parasitoids to evaluate the service of pest regulation provided by plant functional and evolutionary diversity at a time when climate change is expected to trigger more frequent or severe insect outbreaks. This will be done by comparing a group of native flowering plants that are already sold by private companies for bees pollination (or other interests) in terms of their capacity to serve as source of sugar (pollen) for aphid parasitoids while resulting unattractive for their aphid hosts. The best resulting plants will be isolately tested under greenhouse to evaluate their efficiency by measuring the resulting parasitism rate by aphid parasitoids under optimal and extremely hot conditions (summer in Valencia, Spain, where this experiment will be performed during the secondment). Training for me will include experimental design, insect physiology, HPLC analysis, wind tunnel management, insect thermal resistance, plant flower and pollen characterization, plant-insect interactions, statistics and others.", "To": ["2018-01-14, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-01-15"], "Project_ID": ["660593"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITEIT ANTWERPEN"], "EU_Contribution": ["EUR 172 800"], "Project_Title": ["Sustainable Synthesis of Amides"], "Total_Cost": ["EUR 172 800"], "Country": ["Belgium"], "Project_ACR": ["SUSAMIDE"], "Technology_Description": "Despite the ubiquity of the amide group, its synthesis is not always straightforward and the existing methods for amide formation score badly from the perspectives of economy and sustainability. This proposal aims to develop unprecedented methodology for amide synthesis, allowing one to access \u201cchallenging\u201d representatives. Two routes are proposed to mitigate risk and to provide complementarity. The objective of the proposal is twofold: 1) to expand the available chemical space (allowing one to synthesize challenging amides previously considered inaccessible via library synthesis with existing methods) and 2) to substitute existing syntheses with better ones (delivering higher yields without using toxic reagents and minimizing waste). Achieving these two objectives will have an impact on the discovery of new molecular entities and the improvement of production processes in the fine chemicals sector. The power of the new methodology will be demonstrated on the synthesis of selected real-life examples, APIs (Active Pharmaceutical Ingredients).", "To": ["2017-03-31, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-04-01"], "Project_ID": ["657883"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITEIT ANTWERPEN"], "EU_Contribution": ["EUR 160 800"], "Project_Title": ["Towards a fundamental understanding of a gliding arc discharge for the purpose of greenhouse gas conversion into value-added chemicals"], "Total_Cost": ["EUR 160 800"], "Country": ["Belgium"], "Project_ACR": ["GlidArc"], "Technology_Description": "Global climate change due to anthropogenic greenhouse gas emissions is a growing concern. The conversion of greenhouse gases (mainly CO2, CH4) to value-added chemicals or renewable fuels is an effective strategy to reduce these emissions and an interesting process both from economic and ecological point of view. A gliding arc (GlidArc) plasma offers unique perspectives for activating inert molecules at mild conditions and allows the greenhouse gas conversion with limited energy cost. A GlidArc is, however, very complex and poorly understood. Therefore, this project intends to obtain more fundamental insight in the plasma-mechanisms of the GlidArc for greenhouse gas conversion, by means of extensive modeling, validated by experimental diagnostics. First, the chemical kinetics in the GlidArc for greenhouse gas conversion will be studied. Second, this plasma chemistry will be incorporated in a coupled magnetohydrodynamics (MHD) - kinetics model to study the spatial and temporal plasma properties. The model will be validated by experiments, to be carried out during the secondment. Furthermore, the effects of various operating parameters, such as the CH4/CO2 ratio, the discharge power and the gas flow rates, on the gas conversion, the yields of the formed products and on the energy efficiency will be analyzed, in order to predict which conditions give rise to the highest and most energy-efficient conversion. This project is very interdisciplinary, including chemistry, physics, chemical engineering, mathematics and computer modeling, with application in environmental science and sustainable chemistry. Definitely it will extend the applicant\u2019s skills in plasma modeling to a much broader field, with new applications, and enhance his creative and innovative potential by advanced training in an international research environment.", "To": ["2017-06-21, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-06-22"], "Project_ID": ["657304"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Financing Affordable Housing Under Localism"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["REINVEST"], "Technology_Description": "This project explores the urban governance challenge of motivating institutional investment in affordable rental housing for low-middle income households. The high pressure rental markets of US and European urban financial centres, New York, Amsterdam and London, provide sites for the study. The proposers' prior approach to studying hybrid strategies balancing social and commercial aims in housing organizations is extended to institutional investment. This takes us beyond existing studies of financial incentive structures in institutional investment by recognizing the conflicting logics of profit and affordability, and the potential balancing role of localism. Work Package 1 reviews US experience of innovation to attract institutional investment through tax credit incentives and community reinvestment regulation; and uses stakeholder interviews in two European urban centres to identify key local contextual factors and case study sites. Theories of corporate social responsibility, both discretionary and negotiated, are used to develop an evaluation framework for institutionally-funded affordable housing projects. Work Package 2 explores the negotiation and terms of a sample of case study projects using a structured evaluation methodology. Interviews with investors, policymakers and civic stakeholders reveal actor interpretations of governance arrangements that help connect these projects to finance. Investment decisions are related back to the internal logics and structures of investors and to external incentive structures. Governance models are assessed, drawing on concepts of power and legitimacy. Work Package 3 harnesses a partnership with CECODHAS; the leading European social housing umbrella, to convene an expert panel to apply case study findings to European contexts and to achieve impacts beyond the case study settings. This will help to uncover the potential for urban policy to empower civic actors to negotiate finance for local affordable housing projects.", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["661659"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITEIT ANTWERPEN"], "EU_Contribution": ["EUR 172 800"], "Project_Title": ["The impact of intra household decision making on the sustainability, efficiency and equitability of household farming in sub-Saharan Africa."], "Total_Cost": ["EUR 172 800"], "Country": ["Belgium"], "Project_ACR": ["INTRACOF"], "Technology_Description": "This research project will assess to what extent more participatory intra household decision making about production and resource allocation contributes to more sustainable, efficient and equitable household farming systems in sub-Saharan Africa, more specifically coffee farming systems in Uganda and Tanzania. An intervention in which household are intensely coached in participatory decision making about production, resource allocation and income expenditure will be randomly introduced among Ugandan and Tanzanian smallholder coffee farming household. A framed economic experiment will permit to appraise if provision and appropriation behaviour by spouses in households with more participatory intra household decision making, the treatment group, is more cooperative, than in control households. The impact of participatory intra household decision making on the sustainability, efficiency and equitability of the outcomes from provision and appropriation behaviour in household farming systems will be studied with using individual survey data collected among spouses in treatment and control households. Inspired by the methods and findings of this project, a practical monitoring tool will be developed to capture changes in intra household decision making about production and resource allocation and their effect on sustainable, efficient and equitable (coffee) farming in collaboration with one of the partner organisations.", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["702964"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITEIT ANTWERPEN"], "EU_Contribution": ["EUR 93 800"], "Project_Title": ["Imagination and Religious Credence"], "Total_Cost": ["EUR 93 800"], "Country": ["Belgium"], "Project_ACR": ["IRC"], "Technology_Description": "\"Many philosophers and cognitive scientists have a habit of using the word \u201cbelief\u201d as though it refers to a single, simple sort of cognitive attitude. But if we take empirical evidence from cognitive science of religion seriously, we will see that this habit is a source of confusion. Just as it is a mistake in astronomy to assume that Venus and the North Star are the same kind of entity because they are both \u201cstars,\u201d so too it is a mistake in theorizing the nature of belief to treat what I call religious credence and what I call factual belief as the same type of attitude. I have already argued in my paper \u201cReligious Credence is not Factual Belief\u201d (forthcoming, Cognition) that our best psychological theory of cognitive attitudes, in conjunction with psychological and anthropological evidence, will treat these two attitudes differently. The research aim of the project proposed here is to elaborate on my theoretical apparatus to produce a book-length monograph that will serve philosophers and cognitive scientists interested in religious \u201cbelief,\"\" and the corresponding aim for public dissemination is to make this research popularly available through essays, blogs, radio, and public debate. ", "To": ["2016-07-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-06-01"], "Project_ID": ["659912"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITEIT ANTWERPEN"], "EU_Contribution": ["EUR 172 800"], "Project_Title": ["Effects of Institutional Change on Participatory Democracy and the Involvement of Civil Society Organisations"], "Total_Cost": ["EUR 172 800"], "Country": ["Belgium"], "Project_ACR": ["DemocInChange"], "Technology_Description": "\"DemocInChange understands the current challenges to EU integration as an opportunity to rethink the interface of civil society organisations (CSOs) and EU institutions as a basis for supranational participatory democracy. It does so by focusing on CSOs that aim to improve citizenship rights and participation for groups often marginalized in the policy-making process, more precisely by studying the effects of internal EU administrative reorganisation on the participation of CSOs in EU decision- and policy-making. DemocInChange impacts on the future of European integration by contributing to President Juncker's political priority \"A Union of Democratic Change\", making European societies more innovative, inclusive and reflective. It provides a better understanding of the linkages between equality CSOs and EU institutions, the impact of the Commission on CSOs networks and their lobbying options.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["702134"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["FREIE UNIVERSITAET BERLIN"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Higher Epsilon-Factors for Higher Local Fields"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["HEF"], "Technology_Description": "The goal of this project is to extend the work of Beilinson-Bloch-Esnault (BBE) on de Rahm epsilon-factors in dimension one to higher local fields. Together with my collaborators Oliver Braunling and Jesse Wolfson we have carefully studied one of the main tools of BBE, Tate vector bundles, in an abstract context which allows to handle higher-dimensional situations. Moreover, we have successfully constructed a special case of higher epsilon-factors, called higher-dimensional Contou-Carr\u00e8re symbols, and established an array of reciprocity laws for this case. It seems very likely that similar methods, also of K-theoretic nature like in the case of symbols, can be used to shed light on higher de Rahm epsilon-factors, and reciprocity phenomena thereof. The candidate will investigate the connection between the approach via Tate objects, and extend Patel's K-theoretic framework in a compatible way. A higher analogue of Beilinson's topological epsilon-factors is also envisioned, and a comparison result between this theory and the de Rham version. This project offers a new viewpoint on the arithmetic and geometric behaviour of higher local fields.", "To": ["2018-10-16, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-10-17"], "Project_ID": ["701679"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITEIT ANTWERPEN", "UNIVERSITEIT ANTWERPEN"], "EU_Contribution": ["EUR 1 499 425"], "Project_Title": ["Order in one dimension: Functional hybrids of chirality-sorted carbon nanotubes"], "Total_Cost": ["EUR 1 499 425"], "Country": ["Belgium", "Belgium"], "Project_ACR": ["ORDERin1D"], "Technology_Description": "The hollow structure of carbon nanotubes (CNTs) with a wide range of diameters forms an ideal one-dimensional host system to study restricted diameter-dependent molecular transport and to achieve unique polar molecular order. For the ORDERin1D project, I will capitalize on my recent breakthroughs in the processing, filling, chiral sorting and high-resolution spectroscopic characterization of empty and filled CNTs, aiming for a diameter-dependent characterization of the filling with various molecules, which will pave the way for the rational design of ultraselective filtermembranes, sensors, nanofluidic devices and nanohybrids with unseen control over the structural order at the molecular scale. In particular, I recently found that dipolar molecules naturally align head-to-tail into a polar array inside the CNTs, after which their molecular directional properties such as their dipole moment and second-order nonlinear optical responses add up coherently, groundbreaking for the development of nanophotonics applications.", "To": ["2021-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["679841"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["TECHNISCHE UNIVERSITEIT DELFT"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["Flexible Li ion Batteries via Nanocrystal-Nanocarbon Scaffolded Structures"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["FlexBatteries"], "Technology_Description": "The aim of this proposal is to develop next generation flexible high-energy density Li ion batteries. This project seeks to advance this field by developing generalized methodologies to effectively interface flexible nano carbon scaffolds with inorganic nanocrystals, and to obtain tailor made hierarchical assemblies as building blocks. Fabrication of these hierarchical materials whose chemical and mechanical properties can be optimized at the nano, micro and millimeter scale are key to ensure both high energy and power density, and structurally flexible components. Our strategy will significantly increase the loading of electro-active particles (nanocrystals) and maximize their contact/exposure to electrolytes in optimized conditions, which will improve the electrochemical properties of nanostructures. Parallel, by applying in situ electrochemical-Li-NMR-Neutron depth profile and XRD, the proposed multi-scale approach will deepen the understanding of fundamental issues such as Li+ diffusion path ways in nanocrystal-carbon scaffolded structures (Li ion kinetics), volume expansion of nanocrystals (stress/strain issues), thermal management (heat dissipation), gas evolution (via electrolyte decomposition) and various modes of particle degradation during battery charge/discharge cycling.", "To": ["2018-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-08-01"], "Project_ID": ["704659"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITEIT HASSELT", "UNIVERSITEIT HASSELT", "UNIVERSITEIT ANTWERPEN"], "EU_Contribution": ["EUR 1 639 168"], "Project_Title": ["Translational and Transdisciplinary research in Modeling Infectious Diseases"], "Total_Cost": ["EUR 1 639 168"], "Country": ["Belgium", "Belgium", "Belgium"], "Project_ACR": ["TransMID"], "Technology_Description": "TransMID focuses on the development of novel methods to estimate key epidemiological parameters from both serological and social contact data, with the aim to significantly expand the range of public health questions that can be adequately addressed using such data. Using new statistical and mathematical theory and newly collected as well as readily available serological and social contact data (mainly from Europe), fundamental mathematical and epidemiological challenges as outlined in the following work packages will be addressed: (a) frequency and density dependent mass action relating potential effective contacts to transmission dynamics in (sub)populations of different sizes with an empirical assessment using readily available contact data, (b) behavioural and temporal variations in contact patterns and their impact on the dynamics of infectious diseases, (c) close contact household networks and the assumption of homogeneous mixing within households, (d) estimating parameters from multivariate and serial cross-sectional serological data taking temporal effects and heterogeneity in acquisition into account in combination with the use of social contact data, and (e) finally the design of sero- and social contact surveys with specific focus on serial cross-sectional surveys. TransMID is transdisciplinary in nature with applications on diseases of major public health interest, such as pertussis, cytomegalovirus and measles. Translational methodology is placed at the heart of TransMID resulting in the development of a unifying methodology for other diseases and settings. The development of a toolbox and accompanying software allow easy and effective application of these fundamentally improved techniques on many infectious diseases and in different geographic contexts, which should maximize TransMID\u2019s impact on public health in Europe and beyond.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["682540"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["FREIE UNIVERSITAET BERLIN", "FREIE UNIVERSITAET BERLIN"], "EU_Contribution": ["EUR 1 810 747"], "Project_Title": ["Integration of herpesvirus into telomeres: From the mechanism of genome integration and mobilization to therapeutic intervention"], "Total_Cost": ["EUR 1 810 747"], "Country": ["Germany", "Germany"], "Project_ACR": ["INTEGHER"], "Technology_Description": "Herpesviruses cause serious diseases in humans and animals. After initial lytic infection, herpesviruses establish a quiescent (latent) infection, which allows their persistence in the host for life. We and others recently identified a novel mechanism that allows maintenance of the genome of certain herpesviruses during latency, by integrating their complete genetic material into host telomeres. One of these viruses is human herpesvirus 6 (HHV-6) which is associated with seizures, encephalitis, and graft rejection in transplant patients. Sporadic reactivation of the integrated virus ensures continued evolution of the virus as it spreads to a new cadre of susceptible individuals. There are critical gaps in our knowledge regarding the fate of herpesvirus genomes during integration and reactivation as well as of viral and cellular factors involved in these processes.", "To": ["2021-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-04-01"], "Project_ID": ["677673"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["UNIVERSITE DE RENNES I", "UNIVERSITE DE RENNES I"], "EU_Contribution": ["EUR 2 100 230"], "Project_Title": ["Ultrasensitive Chirped-Pulse Fourier Transform mm-Wave Detection of Transient Species in Uniform Supersonic Flows for Reaction Kinetics Studies under Extreme Conditions"], "Total_Cost": ["EUR 2 100 230"], "Country": ["France", "France"], "Project_ACR": ["CRESUCHIRP"], "Technology_Description": "This proposal aims to develop a combination of a chirped-pulse (sub)mm-wave rotational spectrometer with uniform supersonic flows generated by expansion of gases through Laval nozzles and apply it to problems at the frontiers of reaction kinetics.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["695724"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["UNIVERSITE DE RENNES I", "UNIVERSITE DE RENNES I"], "EU_Contribution": ["EUR 1 998 747"], "Project_Title": ["Mixing interfaces as reactive hotspots of porous media flows: theoretical upscaling, experimental imaging and field scale validation"], "Total_Cost": ["EUR 1 998 747"], "Country": ["France", "France"], "Project_ACR": ["ReactiveFronts"], "Technology_Description": "In porous media, mixing interfaces such as contaminant plume fringes or boundaries between water bodies create highly reactive localized hotspots of chemical and microbiological activity, whether in engineered or natural systems. These reactive fronts are characterized by high concentration gradients, complex flow dynamics, variable water saturation, fluctuating redox conditions and multifunctional biological communities. The spatial and temporal variability of velocity gradients is expected to elongate mixing interfaces and steepen concentration gradients, thus strongly affecting biochemical reactivity. However, a major issue with porous media flows is that these essential micro-scale interactions are inaccessible to direct observation. Furthermore, the lack of a validated upscaling framework from fluid- to system-scale represents a major barrier to the application of reactive transport models to natural or industrial problems. ", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["648377"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA", "UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA", "UNIVERSITA DEGLI STUDI DI TRIESTE"], "EU_Contribution": ["EUR 1 254 105"], "Project_Title": ["The Common Core of European Administrative Law"], "Total_Cost": ["EUR 1 254 105"], "Country": ["Italy", "Italy", "Italy"], "Project_ACR": ["CoCEAL"], "Technology_Description": "The European dimension of administrative law is the focus of a flurry of initiatives aiming to investigate similarities and differences, and to shape common legal scenarios. A codification of the administrative procedures of the EU has been envisaged by the European Parliament in its resolution of February 2013. A broader proposal of codification, including rule-making and contractual procedures, has been elaborated by ReNEUAL and has been discussed in a series of workshops in 2015.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["694697"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["FREIE UNIVERSITAET BERLIN", "FREIE UNIVERSITAET BERLIN"], "EU_Contribution": ["EUR 1 997 452"], "Project_Title": ["Unlocking new physics in controllably strained two-dimensional materials"], "Total_Cost": ["EUR 1 997 452"], "Country": ["Germany", "Germany"], "Project_ACR": ["Strained2DMaterials"], "Technology_Description": "\"We will use strain engineering as an enabling tool to study previously inaccessible or hard-to-study phenomena in two-dimensional atomic crystals (2DACs: graphene, bilayer graphene, and monolayer transition metal dichalcogenides). In our first objective, we develop unique experimental tools to control and characterize mechanical strain in 2DACs. These are the distinguishing features of our approach: (i) The use of very low disorder suspended devices; (ii) Both uniform and controlled non-uniform strain will be induced; (iii) The level of strain will be precisely adjusted and determined in-situ during measurements. We will then use controllably-strained samples to study electrical, mechanical, thermal, and optical properties of 2DACs:", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-11-01"], "Project_ID": ["639739"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["FREIE UNIVERSITAET BERLIN", "FREIE UNIVERSITAET BERLIN"], "EU_Contribution": ["EUR 2 390 598"], "Project_Title": ["Gradual and abrupt environmental change: connecting physiology, evolution and community composition"], "Total_Cost": ["EUR 2 390 598"], "Country": ["Germany", "Germany"], "Project_ACR": ["Gradual_Change"], "Technology_Description": "A major goal in ecology is to predict how environmental changes, including drivers of global change, affect communities and ecosystem functioning, with society demanding answers to these pressing questions. A key limitation of virtually all experimental approaches addressing such questions is that treatments are delivered abruptly, while many changes occurring in nature are gradual. Here I propose to comprehensively study consequences of environmental change when delivered abruptly vs. gradually. In order to understand and model effects of gradual vs. abrupt changes, we need to simultaneously consider physiological effects (e.g. acclimation), evolutionary changes (e.g. adaptation) and changes in community composition and functioning. Even though changes at these levels likely interact, there is no study in which physiology, evolutionary changes and community shifts have been studied in response to a changing environmental factor. This research program thus enters unchartered territory of empirical environmental research in proposing work at this nexus of physiology, environmental change and community composition/ function. I focus on soil fungi, key players in terrestrial ecosystems, testing a range of gradually vs. abruptly changing environmental factors, in a range of soils, in the field and in microcosms. We connect differential responses to species traits, apply modeling and employ data syntheses across all biomes and organisms to achieve high external validity. We carry out a set of core experiments that will afford unprecedented insight into the nature of change in a community context in response to warming, focusing on soil fungi. In these we follow evolutionary change (phenotype and genotype), test physiological shifts by re-isolation of fungi and monitor community changes. This work will have transformative character in providing not only new mechanistic insights into effects of environmental change, but will also represent a step change in fungal ecology.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["694368"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["UNIVERSITEIT ANTWERPEN", "UNIVERSITEIT ANTWERPEN"], "EU_Contribution": ["EUR 884 725"], "Project_Title": ["Between saints and celebrities. The devotion and promotion of stigmatics in Europe, c.1800-1950"], "Total_Cost": ["EUR 884 725"], "Country": ["Belgium", "Belgium"], "Project_ACR": ["STIGMATICS"], "Technology_Description": "By far most of the historical studies on the 'golden age' of the stigmatics have focused on medical debates and religious treatises. This project wants to move beyond the traditional historiographical emphasis in at least three ways. First of all, it will focus on the popular perception of stigmatics in the nineteenth and early twentieth century and examine how they became symbolic figures of political and religious causes. Secondly, we will study the interaction of the 'victim souls' with their communities and examine how they were turned into 'living saints' through religious practices and discourse, and how some of them were eventually even beatified and canonized. Thirdly, we will address them as carefully constructed religious commodities (celebrities) and rebalance the research on the selling of religion that has adopted a top-down perspective and focused primarily on the popularization of authorized cults rather than on the impact of the commercialization from the bottom-up. Combining these three aspects in studying the stigmatics, the project will enhance our understanding of the role of (new) media and consumption practices in religious change and the construction of religious identities. As each of these emphases calls for a study that takes into account chronological and geographical differences, we will adopt a comparative approach and examine five of the countries where most of the (hundreds of) stigmatics have been attested (Italy, Spain, France, Germany and Belgium). This will allow us to trace larger trends as changes in the type of stigmatic (e.g. bedridden silent 'sign' or a socially engaged charismatic leader) and moments and locations of increased attention (e.g. political crises). However, since this was the era of an internationalized Catholicism the countries will not be studied in isolation and special attention will be given to transnational attraction (e.g. pilgrims) and the related differences in promotion and perception.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-04-01"], "Project_ID": ["637908"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["UNIVERSIDAD PABLO DE OLAVIDE", "UNIVERSIDAD PABLO DE OLAVIDE"], "EU_Contribution": ["EUR 1 499 625"], "Project_Title": ["Global Encounters between China and Europe: Trade Networks, Consumption and Cultural Exchanges in Macau and Marseille (1680-1840)"], "Total_Cost": ["EUR 1 499 625"], "Country": ["Spain", "Spain"], "Project_ACR": ["GECEM"], "Technology_Description": "In the last decade the approaches of the global history have been emphasized in order to visualize the progress, form and method which historians have undertaken when carrying out ambitious research projects to analyse and compare diverse geographical and cultural areas of Asia and Europe. But when dealing with comparisons and cross-cultural studies in Europe and Asia, some scholarly works have exceeded of ambiguities when defining geographical units as well as chronology. In this project I examine perceptions and dialogues between China and Europe by analysing strategic geopolitical sites which fostered commerce, consumption and socioeconomic networks between China and Europe through a particular case study: Macau, connecting with South China, and Marseille in Mediterranean Europe. ", "To": ["2021-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-07-01"], "Project_ID": ["679371"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI TRIESTE", "UNIVERSITA DEGLI STUDI DI TRIESTE", "ELETTRA - SINCROTRONE TRIESTE SCPA"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["INhomogenieties and fluctuations in quantum CohErent matter Phases by ultrafast optical Tomography"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Italy", "Italy", "Italy"], "Project_ACR": ["INCEPT"], "Technology_Description": "Standard time domain experiments measure the time evolution of the reflected/transmitted mean number of photons in the probe pulses. The evolution of the response of a material is typically averaged over the illuminated area as well as over many pump and probe measurements repeated stroboscopically. The aim of this project is to extend time domain optical spectroscopy beyond mean photon number measurements by performing a full Time Resolved Quantum State Reconstruction (TRQSR) of the probe pulses as a function of the pump and probe delay. The nature of the light matter interaction and the transient light-induced states of matter will be imprinted into the probe quantum state after the interaction with the material and can be uncovered with unprecedented detail with this new approach to time domain studies.", "To": ["2021-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2016-06-01"], "Project_ID": ["677488"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["UNIVERSITY OF BRISTOL", "UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 2 009 429"], "Project_Title": ["Photonic Quantum Computing"], "Total_Cost": ["EUR 2 009 429"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["PQC"], "Technology_Description": "This CoG will simultaneously address the outstanding research challenges to establishing the feasibility of large-scale photonic quantum computing by:", "To": ["2020-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-06-01"], "Project_ID": ["648667"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["UNIVERSITEIT HASSELT"], "EU_Contribution": ["EUR 240 530,40"], "Project_Title": ["Spillover of Leptospira in island populations of the Channel Island fox"], "Total_Cost": ["EUR 240 530,40"], "Country": ["Belgium"], "Project_ACR": ["SpiL"], "Technology_Description": "Spillover, or cross-species transmission, of pathogens from wildlife to humans is the major cause of emerging infectious diseases such as HIV, Ebola virus or SARS. Yet despite this relevance spillover as a natural process is little known, and there is a pressing need for general theory on spillover. We propose to develop a new conceptual framework for spillover, by using an interdisciplinary approach to analyse an exceptionally complete dataset of Leptospira spillover from California sea lions to endangered Channel Island foxes. Guided by the OneHealth vision, we will combine concepts and methods from human epidemiology, disease ecology and island biology to create a model of Leptospira spillover risk that will provide a unique opportunity to develop and extract general concepts. Through this process, Borremans, the applying experienced researcher, will acquire a strong set of skills that will boost his expertise and significantly advance his professional profile. He will be guided by two high-profile researchers, Lloyd-Smith (UCLA) and Hens (UHasselt) and will benefit from collaborations through their extensive international networks, ensuring Borremans\u2019 visibility at an international level.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["707840"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["INSTITUTO SUPERIOR DE ENGENHARIA DO PORTO", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "UNINOVA-INSTITUTO DE DESENVOLVIMENTO DE NOVAS TECNOLOGIAS-ASSOCIACAO", "Teknologian tutkimuskeskus VTT Oy", "AARHUS UNIVERSITET"], "EU_Contribution": ["EUR 3 346 660"], "Project_Title": ["INNOVATIVE AUTONOMOUS ELECTRICAL BIOSENSOR SYNERGISTICALLY ASSEMBLED INSIDE A PASSIVE DIRECT METHANOL FUEL CELL FOR SCREENING CANCER BIOMARKERS"], "Total_Cost": ["EUR 3 346 660"], "Country": ["Portugal", "United Kingdom", "Portugal", "Finland", "Denmark"], "Project_ACR": ["Symbiotic"], "Technology_Description": "Biosensors possess recognition elements that bind to target molecules which lead to detectable signals; they are made of two basic components: (i) a bioreceptor or biorecognition element; and (ii) a transducer element. The bioreceptor system interacts with the target analyte and this interaction is monitored by the transducer, which converts the information into a measurable effect such as an electrical, optical or mass-sensitive signal.", "To": ["2018-05-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-1-2014 - FET-Open research projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Portugal"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2015-06-01"], "Project_ID": ["665046"], "Call_for_Proposal": ["H2020-FETOPEN-2014-2015-RIA"]}, -{"Partners": ["UNIVERSITEIT ANTWERPEN", "UNIVERSITEIT ANTWERPEN"], "EU_Contribution": ["EUR 1 208 025"], "Project_Title": ["Mind-Bending Grammars: The dynamics of correlated multiple grammatical changes in Early Modern English writers"], "Total_Cost": ["EUR 1 208 025"], "Country": ["Belgium", "Belgium"], "Project_ACR": ["MindBendingGrammars"], "Technology_Description": "Mind-Bending Grammars examines change in mental grammars of 17th century individuals across their lifespan as attested in their writings. The project treats grammar as a self-organizing network of form-meaning schemas continuously fine-tuning itself, where activating one schema may prime formally or functionally associated ones. In analyzing multiple grammar changes in healthy adults it aspires to make a breakthrough in the cognitive modelling of grammar, and is expected to bear on views of cognitive plasticity and self-organizing systems (e.g. ecosystems). To reach these goals it will determine (i) how change in one part of an individual\u2019s grammar relates to change in another; (ii) to what extent grammar change in individuals is possible and attested beyond childhood. This is still unsettled. Formal models hold that change occurs in language acquisition, social ones that it mainly results from adult interaction. The first ignore too much adult usage, the second grammar as a system. ", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["639008"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Aerodynamic Lift force of Trains subjected to cross winds\u2014get it right!"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["LiftTrain"], "Technology_Description": "A European-wide move to standardize the criteria for certification of railway vehicles has lead to the development of regulations for rail operators regarding velocities and pressures generated by trains and on train in cross winds. There are two approved methodologies currently used in these regulations; physical modeling using the wind tunnel experiments and numerical modeling using computational fluid dynamics (CFD) techniques. Although there are different types of CFD techniques, yet all of them suffer the lake of accuracy in predicting the values of the experimental lift force resulting on either overestimation or underestimation of the rolling moment coefficient. The aim of this innovative Fellowship is to develop an accurate numerical technique based on the steady Reynolds Average Navier Stocks (RANS) capable of accurately predict the aerodynamic forces. The methodology will be based on wind tunnel experiments, moving model testing and different types of steady and unsteady CFD techniques. In this project we will investigate for the first time the effect of surface roughness on the lift force prediction of a train subjected to cross wind. Building on the complementary skills of the Experienced Researcher (ER) (numerical modeling) and the Beneficiary (CFD & physical modeling), we will extend significantly the existing knowledge of modeling trains on smooth surface to include a novel numerical technique to simulate the surface roughness and hence better estimate the lift force coefficient. Our work will be validated using wind tunnel experiment at POLIMI, ITALY and underpinned with those at our industrial collaborator, Interfleet and academic partner Chalmers, Sweden. Success will define improvements to prediction of the lift force coefficient in both physical experiments and CFD modeling, offering tangible environment and financial benefits and providing an exceptional training opportunity for the ER.", "To": ["2018-12-07, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-12-08"], "Project_ID": ["701693"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITEIT ANTWERPEN", "KATHOLIEKE UNIVERSITEIT LEUVEN", "KUNGLIGA TEKNISKA HOEGSKOLAN", "STOCKHOLMS UNIVERSITET", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "BIOMERIEUX SA", "BIOCARTIS NV"], "EU_Contribution": ["EUR 3 860 507,52"], "Project_Title": ["New Diagnostics for Infectious Diseases: \u201cND4ID\u201d"], "Total_Cost": ["EUR 3 860 507,52"], "Country": ["Belgium", "Belgium", "Sweden", "Sweden", "Spain", "Switzerland", "France", "Belgium"], "Project_ACR": ["ND4ID"], "Technology_Description": "Infectious diseases are a major burden to public health and the global economy, not in the least due to antimicrobial resistance. Rapid point of care (POC) in vitro diagnostics (IVD) are key tools in the effective clinical management of patients with infectious diseases. Yet there is still a large unmet clinical need for more rapid POC IVDs generating more clinically relevant, actionable information. Effectively addressing this need requires a change in the current approach in training researchers on IVDs, generating a new \u2018breed\u2019 of IVD researchers capable of closing the gap between the clinical and technological perspective. ND4ID takes up this challenge by offering 15 ESRs a world-class first of its kind training programme where they will be exposed to the full breadth of disciplines spanning clinical, technological and market-oriented viewpoints, from both the academic and non-academic sector. Through a set of synergistic research projects on novel POC assays, targeting the most important and urgent clinical needs at world leading academic or private sector research groups, the ESRs are offered a holistic training program, preparing them to be lead players in the future IVD field. This training through research is augmented by a unique comprehensive network-wide training programme covering clinical, technical and translational knowledge and skills of relevance to IVD research, development and exploitation. As such, ND4ID will deliver ESRs that will be in high demand serving as an example for other academic and non-academic actors active in training IVD researchers and further strengthening Europe\u2019s position in the internally competitive arena of IVD technology.", "To": ["2020-02-29, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-03-01"], "Project_ID": ["675412"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["UNIVERSITEIT ANTWERPEN"], "EU_Contribution": ["EUR 160 800"], "Project_Title": ["Computer modelling and experimental validation of plasmas and plasma- surface interactions, for a deep insight in cryogenic etching"], "Total_Cost": ["EUR 160 800"], "Country": ["Belgium"], "Project_ACR": ["Cryoetch"], "Technology_Description": "Microchips have caused a revolution in electronics over the last few decades. Following Moore's law, much effort has been put into continuously shrinking electronic feature dimensions. Indeed, typical feature sizes of semi-conductor decreased from 10 \u00b5m in 1971 to 14 nm in 2014. With the shrinkage of feature sizes, plasma etching plays a more and more important role due to its anisotropy during surface processing.", "To": ["2018-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["702604"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITE DE RENNES I"], "EU_Contribution": ["EUR 119 901,60"], "Project_Title": ["Single Molecule Magnets light-switching with photochromic ligands"], "Total_Cost": ["EUR 119 901,60"], "Country": ["France"], "Project_ACR": ["PhotoSMM"], "Technology_Description": "The integration of molecular-scale components in circuits may ultimately allow the replacement of silicon-based electronics by high speed systems with low energy consumption. Because of the prominent use of magnetization-based information storage technologies in our daily life, Single-Molecule-Magnets (SMM), which are able to interconvert between two states with opposite magnetization directions receive a great deal of attention. The potential is huge for SMM systems that would demonstrate magnetic field- and light-driven changes in both their optical and magnetic properties because they could reproduce on a single molecule the same type of magneto-optical (MO) effects which are used for some current data storage technologies. Photo-SMM will demonstrate that a light input can induce a modification of the magnetic and optical properties of monometallic or bimetallic SMM. This will be achieved thanks to the unprecedented association of anisotropic ions with photochromic ligands designed to produce very different coordination environments in their two isomeric states, thus maximizing the impact of photo-isomerization on the ligand field experienced by the 4f or 3d metal ions and on the resulting magnetic behavior.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["700819"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITE DE RENNES I"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Advancing Apatite Thermochronology: Novel analytical approaches for high eU apatites."], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["AAT-NAA"], "Technology_Description": "Low temperature thermochronometry (LTT) dating is a powerful tool in geoscience, used worldwide, to provide unique information on the thermal history of rocks. Using these insights geologists can achieve a better understanding of geological processes that have occurred over million year timescales even in settings where erosion has removed much of the geological record. Despite the success of these techniques in tackling geological problems, there still exists a major gap in our knowledge over the fundamental principles that underlie these dating systems. Much of this uncertainty stems from an incomplete understanding of inter and intra-crystal compositional variation and the influence this has on the kinetics of the dating system. Reaching a complete understanding of crustal thermal histories also remains a major challenge as the lowest temperature thermochronometers, apatite fission track (AFT) and apatite (U-Th)/He (AHe), are only sensitive over a temperature range of c. 120 \u2013 40\u00b0C. The lower temperature limit of this range is also dependant on apatites having low degrees of radiation damage that can enhance retention of He within apatite. This project will advance AFT and AHe methodology by focusing on apatites enriched in U and Th from geological settings considered stable. The first goal is to obtain detailed REE compositional analysis using LA-ICP-MS to refine fission track annealing models and obtain high precision measurements of parent elements to improve AFT age data. The second goal is to ensure that the maximum amount of thermal history information is extract from the 4He concentration profile in the apatite crystal. This will be achieved by a combination of 4He/3He analysis and multi-single-grain AHe analysis of broken apatite crystals. By achieving these two goals the project will advance methodology, establish analytical capabilities at the host organisation and provide new insights into the thermal history of the crust at stable geological settings.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["706976"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["FREIE UNIVERSITAET BERLIN"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Glass, Faience and Food in Late Bronze Age Societies: An Analysis of the Socio-Economics of Urban Industries in Egyptian and Mesopotamian settlements"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["GLASS"], "Technology_Description": "This project aims to establish an in-depth understanding of the administration and control of high-temperature industries on an urban level and the socio-economic relationship between the elite and the non-elite members of society in Late Bronze Age (LBA) Egypt and Mesopotamia (c. 1650-1050 BC). It has been recognised in the past that within the urban settlements of Egypt and Mesopotamia the production of basic faience- and glass-objects frequently occurred in the same urban domestic context as that of foodstuffs, using the same tools and firing structures. This analysis will particularly highlight how elite control influenced these domestic industries in an urban setting, and to what extent this influenced the role of the members of a non-elite population and the urban infrastructure. The project will examine the following aspects: (1) The spatial analysis of the relationship between the production of glass artefacts and that of faience goods and foodstuffs using Geographical Information Systems (GIS) technology: Concentrating on the New Kingdom Egyptian settlement of Amarna, domestic and administrative archaeological contexts containing a combination of glass-working, faience manufacture and food production will be identified, documented and analysed in detail. (2) The organisation of workshops and areas of industrial activity throughout the urban sites and their infrastructures, within both LBA Egypt and Mesopotamia: This will also be done using GIS, but will also include published and unpublished materials and contemporary textual sources providing knowledge about urban workshops and domestic industrial settings. (3) A comparison of industrial activities within ancient Egyptian settlements and those taking place in contemporary ancient Mesopotamian settlement and palace sites. (4) Export and trade facilities and networks, in order to demonstrate how the produce of these industries was consumed, transported and, possibly, traded.", "To": ["2017-09-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["653188"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITEIT ANTWERPEN"], "EU_Contribution": ["EUR 160 800"], "Project_Title": ["Understanding Nitrous Oxide Production from The Mainstream Partial Nitritation and Anammox Process"], "Total_Cost": ["EUR 160 800"], "Country": ["Belgium"], "Project_ACR": ["N2OPNA"], "Technology_Description": "Sustainable nitrogen removal from wastewater is of increasing significance in the future, aiming to achieve savings of energy consumption and operational cost as well as minimized emission of greenhouse gases. Under such a context, the proposal of N2OPNA is developed to give first insights into nitrous oxide (N2O) production, a potent greenhouse gas, from the mainstream partial nitritation and Anammox (PNA) process. The influencing factors such as sludge particle size, dissolved oxygen, nitrite, hydroxylamine and inorganic carbon will be investigated using enriched granular ammonia oxidizing bacteria (AOB) and Anammox bacteria. Isotopic technique will be applied to shed some light on the transformation of N2O production pathways under varying operational conditions. Based on the process and isotopic data obtained from experiments, an integrated mathematical model for predicting N2O production in PNA system with the consideration of electron transfer, energy balance and bacterial growth will be established. The findings in this proposal would be beneficial for the design and operation of full-scale wastewater treatment plant with the aim of N2O mitigation.", "To": ["2018-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-11-01"], "Project_ID": ["708592"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITE DE RENNES I"], "EU_Contribution": ["EUR 246 668,40"], "Project_Title": ["Molecular 'Click-tronics': Surface-based synthesis of single-molecule electronic components"], "Total_Cost": ["EUR 246 668,40"], "Country": ["France"], "Project_ACR": ["MOLCLICK"], "Technology_Description": "How can single-molecules be best utilized in electronics? Feature sizes of integrated circuits will reach this scale in 10-20 years (Moore\u2019s Law). Typical molecular studies involve surface self-assembled components first synthesised elsewhere (ex situ). Yet surface-based (in situ) preparations offer several distinct synthetic advantages \u2013 also simplifying the construction of otherwise difficult to prepare asymmetrical surface-bound motifs.", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["657247"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["SVERIGES LANTBRUKSUNIVERSITET"], "EU_Contribution": ["EUR 173 857,20"], "Project_Title": ["Hot-spots of Phosphorus and Nitrogen delivery in Time and Space in agricultural catchments"], "Total_Cost": ["EUR 173 857,20"], "Country": ["Sweden"], "Project_ACR": ["HotPaNTS"], "Technology_Description": "Growing food demand exacerbates negative impacts of agriculture on the environment including diffuse nutrient losses from agricultural land to surface and groundwaters causing their eutrophication. The research will evaluate a robust monitoring method of detecting diffuse pollution in space and time in agricultural catchments based on in situ fluorescence sensors. Tangible advantages of the fluorescence sensors: in situ deployment, low cost, real-time measurements, mobility within the catchment, sensitivity and reliability, will be evaluated against potential limitations from quenching effects. This comprehensive evaluation is possible thanks to the host\u2019s unique expertise and role as a coordinator of the Swedish monitoring programme with access to the monitoring catchments, covering a range of agronomic and environmental conditions. Once tested over hot-spots and hot-moments of nutrient delivery, the method could offer an alternative and/or complementary monitoring approach to the existing methodologies of low-frequency and fixed-location nutrient sampling. The tool will improve targeting nutrient sources and mitigation measures to the locations in which they will bring the largest economical, societal and environmental benefits and in turn will help to achieve the aims of the EU Water Framework Directive.", "To": ["2017-12-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["657192"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["FREIE UNIVERSITAET BERLIN"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Neurocomputational mechanisms underlying age-related performance changes in goal-directed decisions from experience"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["AGERISK"], "Technology_Description": "The ability to make goal-directed decisions concerning one\u2019s general well-being declines in later life. The primary\u2014and potentially improvable\u2014factor impacting this decline in decision-making performance is the learning process that precedes a decision. However, little is known about age-related changes in the neurocomputational mechanisms that underlie these learning processes. The goal of the proposed project is to identify these changes. The project will first identify age-related variability in decision-making performance across individuals and task environments, and then test what computational models from artificial intelligence best explain this variability. Because previous research has shown that decision-making performance declines as the complexity of the choice environment increases, the focus will be on performance in cognitively demanding environments that require goal-directed decisions from experience. The project will combine data from lab-based and home-based neurocognitive experiments, capitalizing on new developments in online experiments and webcam based eye tracking. The applicant\u2019s unique research background brings the interdisciplinary range of skills together that is required for the project, combining experience in computational modelling techniques from artificial intelligence, large-scale data analysis from computational linguistics, and neurocognitive experiments. The proposed project promises to further the scientific understanding of the functional link between aging and decision-making performance. Its findings will ultimately help to empower aging decision makers to navigate cognitively demanding choice environments.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["708507"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITY OF NEWCASTLE UPON TYNE", "INSTITUT POLYTECHNIQUE DE GRENOBLE", "UNIVERSITAT POLITECNICA DE CATALUNYA", "UNIVERSITAET FUER BODENKULTUR WIEN", "ITASCA CONSULTANTS", "ITASCA CONSULTING LTD", "UNIVERSITE GRENOBLE ALPES", "THE UNIVERSITY OF WARWICK"], "EU_Contribution": ["EUR 1 804 500"], "Project_Title": ["Geohazards: Risk Assessment, Mitigation and Prevention"], "Total_Cost": ["EUR 2 146 500"], "Country": ["United Kingdom", "France", "Spain", "Austria", "France", "United Kingdom", "France", "United Kingdom"], "Project_ACR": ["GEO-RAMP"], "Technology_Description": "This proposal aims to provide a step change in terms of our capacity to assess and predict risks due to geohazards (landslides and rock slides, earthquakes, floods). This is necessary in order to make built environments and infrastructures resilient to the increasing threat of natural hazards due to the expanding size of European cities and urban centres, increased use of infrastructure, and the effect of increased climatic variations. To achieve this we will bring together the complementary expertise of world leading academic groups in geotechnical, geoenvironmental and seismic engineering, soil and rock mechanics, seismology, hydrology, geology together with private engineering software companies. ", "To": ["2019-03-31, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-04-01"], "Project_ID": ["645665"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["UNIVERSITAET INNSBRUCK", "ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON", "UNIVERSITEIT ANTWERPEN", "BIONORICA RESEARCH GMBH", "GALENICA FARMAKEFTIKI VIDMICHANIA ANONYMOS ETAIRIA", "VIVACELL BIOTECHNOLOGY GMBH", "ROUSSELET CENTRIFUGATION SA", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "UNIVERSITE DE GENEVE"], "EU_Contribution": ["EUR 1 224 000"], "Project_Title": ["Novel natural products for healthy ageing from Mediterranean diet and food plants of other global sources"], "Total_Cost": ["EUR 1 224 000"], "Country": ["Austria", "Greece", "Belgium", "Austria", "Greece", "Germany", "France", "Switzerland", "Switzerland"], "Project_ACR": ["MediHealth"], "Technology_Description": "The main goal of the MediHealth project is to introduce a novel approach for the discovery of active agents of food plants from Mediterranean diet and other global sources to promote healthy ageing. This will be achieved through an extended and well-balanced scheme of researcher\u2019s secondments between 5 universities and 4 enterprises from EU & Associated countries as well as 4 universities from Third countries. A mutual scientific project developed on the needs and interests of both sectors exploiting the existing complementary expertise will be the base of this proposal. Plants from the Mediterranean diet and food plants from TC will be rationally selected and will be subjected to an integrated, interactive and comprehensive platform including in silico, in vitro (advanced cell-based assays), in vivo (flies and mice models) & metabolism assessment. Advanced analytical techniques will embrace the pharmacological evaluation process for the efficient isolation and identification of bioactive plant constituents. Pharmacological profiling of bioactive natural products as well as identification and synthesis of their metabolites will be carried out. Finally, to carry to the stage of development innovative products in the area of nutraceuticals/dietary supplements process-optimization studies will be performed. Within this project, core scientific multidisciplinary knowledge from different research areas will be integrated creating valuable synergies. Expertise will be transferred by means of the seconded researchers training in environments with different research orientation where complimentary skills are required. Special attention will be given to dissemination activities aiming to public awareness of benefits of healthy diet(s). MediHealth aspires to comprise a successful model promoting considerably researchers\u2019 competences and long-lasting collaboration between Industry and Academia generating innovation potential at the European and global levels.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["691158"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["TARTU ULIKOOL", "UNIVERSITE DE CERGY-PONTOISE", "LINKOPINGS UNIVERSITET", "TECHNISCHE UNIVERSITAT DARMSTADT", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "QUEEN MARY UNIVERSITY OF LONDON", "UNIVERSIDAD POLITECNICA DE CARTAGENA", "TECHNISCHE UNIVERSITEIT DELFT", "UNIVERSITE PARIS DIDEROT - PARIS 7", "IVTECH SRL", "ARQUIMEA INGENIERIA S.L", "ESTROTECH OU"], "EU_Contribution": ["EUR 3 300 160,68"], "Project_Title": ["MICroACTuators"], "Total_Cost": ["EUR 3 300 160,68"], "Country": ["Estonia", "France", "Sweden", "Germany", "France", "United Kingdom", "Spain", "Netherlands", "France", "Italy", "Spain", "Estonia"], "Project_ACR": ["MICACT"], "Technology_Description": "Electroactive polymers (EAP) consist of materials capable of changing dimensions and/or shape in response to electrical stimuli. Most EAPs are also capable of generating electrical energy in response to applied mechanical forces. These polymeric materials exhibit properties well beyond what conventional metal or plastic-based actuators can offer, including very high mechanical flexibility (can be stretched to twice their initial size), low density, a high grade of processability, scalability, microfabrication readiness and, in most cases, low cost. Micro-EAPs enable a new broad range of applications for which large strains and forces are desirable, and for which built-in intelligence is necessary.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Estonia"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["641822"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["HELSINGIN YLIOPISTO"], "EU_Contribution": ["EUR 191 325,60"], "Project_Title": ["Migration, Shadow Economy and Parallel Legal Orders in Russia"], "Total_Cost": ["EUR 191 325,60"], "Country": ["Finland"], "Project_ACR": ["MIGRANT LAW RUSSIA"], "Technology_Description": "The overall aim of this fellowship is to train and develop an early career researcher through a research project that focuses on undocumented labour migrants\u2019 legal culture and socio-legal integration in a politically hybrid regime. The project uses the case of Russia, a hybrid political regime and the world\u2019s second largest recipient of labour migrants, to investigate how undocumented migrants negotiate and manoeuvre around the restrictive socio-legal environment through producing new ways of informal governance and legal order. The project aims to accomplish the following three objectives: (1) to develop a theoretically robust understanding of undocumented migrants\u2019 socio-legal integration in politically hybrid regimes\u2019; (2) to produce new ethnographic material about the relationship between undocumented migrants, employers, law-enforcement structures and protection rackets (i.e. \u2018parallel legal orders\u2019) in the Russian migrant labour market and situate these processes within a broader governance and rule of law debate; and (3) to advance the applicant\u2019s research skills, theoretical development and professional maturity. These objectives will be accomplished through a structured and individually tailored research and career development programme. Academically, the objectives will be achieved by exploring undocumented labour migrants\u2019 legal culture and socio-legal integration in the context of Russia. To accomplish the career development objectives, the applicant will obtain advanced training in qualitative and ethnographic research methods that will enable him to exploit empirical research for theoretical development and publications. The objectives pertinent to the work programme are as follows: they provide a solid foundation for research training and data collection, which in turn is utilised for publications and a grant application (ERC Starting Grant), which play a pivotal role in the applicant\u2019s career advancement and consolidation of his research profile.", "To": ["2020-02-29, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["751911"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["BOURNEMOUTH UNIVERSITY", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSITE D'ARTOIS"], "EU_Contribution": ["EUR 1 705 500"], "Project_Title": ["High Dimensional Heterogeneous Data based Animation Techniques for Southeast Asian Intangible Cultural Heritage Digital Content"], "Total_Cost": ["EUR 1 705 500"], "Country": ["United Kingdom", "France", "France"], "Project_ACR": ["AniAge"], "Technology_Description": "\"Although computer animation technology has been extensively used for films and games, it remains largely labour-intensive and expensive, with recent blockbuster films (e.g. Avatar, Gravity) costing around $1 million per minute of footage. A lot of research efforts and technological breakthroughs are therefore necessary if it is to be widely applied to many low-cost applications, such as archiving and reproducing style-preserved intangible cultural heritage (ICH) contents. The project \u201cAniAge\u201d is designed to answer this very challenge, using Southeast Asian ICH as the main application. Southeast Asian ICHs, e.g. local dances and puppetry, are visually and culturally rich, but are unfortunately disappearing due to the globalized modernization. The overall aim of \"AniAge\" is two-fold. The first is to develop novel techniques and tools to reduce the production costs and improve the level of automation without sacrificing the control of the artists, in order to preserve the performing art related ICHs of Southeast Asia. This involves capturing and processing versatile visual performance data, which are heterogeneous in nature and gigantic in quantity. Two areas of technological innovation are aimed to be made, which are novel algorithms for 3D computer animation; and visual asset management with data analytics and machine learning techniques. The second is to promote knowledge exchange and dissemination between EU and Southeast Asian partners, with a view to fostering researchers and spreading knowledge. This will be achieved by having researchers participating in the well-designed research projects, workshops, seminars and open lectures. This consortium consists of six partners, two from the EU and four from Southeast Asia. Four work packages are designed, three for technological developments (digitalizing traditional performing arts - \"DigAge\", digital asset management - \"ManD\" and stylized animation production - \"AniX\") and one for dissemination (\"Dissem\").\"", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["691215"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["FREIE UNIVERSITAET BERLIN"], "EU_Contribution": ["EUR 159 795,60"], "Project_Title": ["Combining electrophysiology and cognitive computational modeling in research on meaning in language"], "Total_Cost": ["EUR 159 795,60"], "Country": ["Germany"], "Project_ACR": ["Modeling ERPs"], "Technology_Description": "Language and meaning processing have been investigated with event-related brain potentials (ERPs), providing direct time-resolved measures of electrical brain activity, and with connectionist network models, providing mechanistic implementations of the assumed processes. However, there has been very little contact between these fields, even though a combination of both methods could be highly beneficial. Based on initial evidence from the applicant, the present project therefore aims to integrate ERPs and computational models in research on language and meaning.", "To": ["2017-07-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-08-01"], "Project_ID": ["658999"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["BOURNEMOUTH UNIVERSITY"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Objective-based forecast evaluations for crude oil volatility."], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["FOROIL"], "Technology_Description": "Oil price volatility forecasting is of major importance due to the financialisation of the oil market and the fact that the oil market participants\u2019 decisions are based on such forecasting (e.g. oil-intensive industries, policy makers, portfolio traders, etc). Currently, forecasters predict oil price volatility using GARCH and HAR models and evaluate the performance of these models using statistical loss-functions, such as the Mean Absolute Predictive Error. Even more, the literature concentrates mainly its attention on two measures of volatility, namely the conditional volatility and the realized volatility. ", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["746025"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["TECHNISCHE UNIVERSITAET WIEN"], "EU_Contribution": ["EUR 166 156,80"], "Project_Title": ["Infinite-dimensional symmetries, black holes, and holography"], "Total_Cost": ["EUR 166 156,80"], "Country": ["Austria"], "Project_ACR": ["HoloBH"], "Technology_Description": "The study of infinite-dimensional symmetries has become a very important theoretical tool in high energy physics. Playing a fundamental role within the context of AdS/CFT holographic correspondence, infinite-dimensional symmetries and their associated mathematical structures have recently reappeared with renewed forms and in a large variety of setups, suggesting an expansion of the scope of the holographic paradigm. Carrying extremely rich information, the algebraic architecture of field theories with infinite symmetries has led to disclose unexpected interrelations between seemingly disconnected results of theoretical physics; such as the relation between soft graviton theorems and the asymptotic symmetries of flat spacetimes, or the conformal invariance governing the near horizon physics of highly spinning black holes. This research project is aimed at investigating different applications of infinite-dimensional symmetries and holography in theoretical physics, with the main attention focused on black hole physics. Specific problems to be addressed include: a) the microscopic computation of non-supersymmetric black holes thermodynamics in non-AdS spaces; b) the exploration of viable extensions of AdS/CFT correspondence to non-AdS spaces, including both warped deformations of AdS, alternative asymptotics for Kerr/CFT, and asymptotically flat spacetimes at null infinity; c) infinite-dimensional symmetries emerging at the near horizon region of non-extremal black holes. This project includes both the transfer of knowledge and skills to the host institution and the training of the researcher in new advanced techniques in the field. As major impacts, the proposal will enhance the future career prospects of the researcher, due to the outstanding training provided by the host, as well as foment further collaborations between the host and other European institutions in the field.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["746297"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["USTAV FYZIKALNI CHEMIE J. HEYROVSKEHO AV CR, v. v. i.", "UNIVERSITEIT LEIDEN", "KOBENHAVNS UNIVERSITET", "AALTO-KORKEAKOULUSAATIO", "AVANTIUM CHEMICALS BV", "INDUSTRIE DE NORA SPA-IDN", "FUNDACIO PRIVADA INSTITUT CATALA D'INVESTIGACIO QUIMICA"], "EU_Contribution": ["EUR 3 616 665,12"], "Project_Title": ["Electrochemical Conversion of Renewable Electricity into Fuels and Chemicals"], "Total_Cost": ["EUR 3 616 665,12"], "Country": ["Czech Republic", "Netherlands", "Denmark", "Finland", "Netherlands", "Italy", "Spain"], "Project_ACR": ["ELCOREL"], "Technology_Description": "ELCOREL is a consortium combining 5 academic and 2 industrial beneficiaries aimed at training young researchers in the field of the conversion of water and carbon dioxide to fuels and chemicals with the aid of electrocatalysts, of prime importance to the efficient large-scale storage of the excess renewable electricity. The consortium will (i) develop rational catalyst design principles for the electrochemical oxidation of water and the electrochemical reduction of carbon dioxide based on the principles of quantum chemistry and large-scale quantum-chemical calculations, (ii) prepare, synthesize, characterize and test model single-crystalline and nanoparticulate catalysts, and (iii) implement high surface area catalysts in large-scale electrolysers at industrial laboratories. The fellows to be employed in ELCOREL will be part of a unique network of academic and industrial world leaders in their respective expertises, and will receive a dedicated multidisciplinary and intersectoral training through mandatory extensive training and research periods at the non-academic partners. Furthermore, they will go through an extensive training programme balancing scientific, personal and entrepreneurial skills. ELCOREL will generate a new generation of electrochemical researchers ready to deal with the academic and industrial challenges of securing Europe\u2019s future energy independence.", "To": ["2021-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Czech Republic"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations"], "From": ["2017-05-01"], "Project_ID": ["722614"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["FUNDACAO CALOUSTE GULBENKIAN"], "EU_Contribution": ["EUR 148 635,60"], "Project_Title": ["Role of alternative splicing in cell expansion and plant growth"], "Total_Cost": ["EUR 148 635,60"], "Country": ["Portugal"], "Project_ACR": ["AS-CELLEXPAND"], "Technology_Description": "Plant growth and morphogenic changes in response to developmental and environmental cues depend on the capacity of cells to expand correctly, which requires structural remodeling of cell walls. Importantly, abiotic stress markedly impacts plant growth by affecting many aspects related to the cell wall, from its composition to the expression of biosynthetic and remodeling genes. The importance of transcriptional regulation of genes controlling cell wall biosynthesis and architecture in response to environmental cues is well studied, but little is known about posttranscriptional mechanisms that affect their function. SR (serine/arginine-rich) proteins are major regulators of alternative splicing (AS), which generates multiple transcripts from the same gene and may modulate plant stress responses. Given evidence that (i) abiotic stress affects SR protein function; (ii) mutations in SR genes cause abnormal plant growth; and (iii) SR45 directly binds mRNAs encoding cell wall regulators, this project will investigate a role for SR-mediated regulation of AS events in cell wall regulators during plant development and abiotic stress responses. Specific objectives are to: (i) identify AS events in cell wall regulator genes that may impact plant growth; (ii) study their regulation by SR proteins; and (iii) assess whether they determine normal plant growth under environmental stress.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Portugal"], "Activity": ["Research Organisations"], "From": ["2018-09-01"], "Project_ID": ["750469"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI TORINO"], "EU_Contribution": ["EUR 1 412 640"], "Project_Title": ["PhD Technology Driven Sciences: Technologies for Cultural Heritage"], "Total_Cost": ["EUR 2 825 280"], "Country": ["Italy"], "Project_ACR": ["T4C"], "Technology_Description": "T4C is a novel research and training doctoral programme in \u201cHeritage Sciences\u201d conceived by the University of Torino, (UNITO) with the financial support of the banking foundation Compagnia di San Paolo (CSP) and the scientific and training involvement of a 35 local, national and international partner organisations belonging to academic and non-academic sectors. Main aim of T4C is to build up the next generation of Cultural Heritage professionals, able to develop technological solutions and services for the restoration, the protection, the diagnostics and the valorization of cultural heritage and skilled with a complementary scientific training from socio-economic disciplines and humanities and soft skills. Target are early stage researchers with a scientific background in chemistry, physics, biotechnology, ICT, biology and related disciplines, undergoing a genuine mobility to Italy. T4C will last 60 months and will be implemented through 2 calls for applications, assigning a total of 18 transnational incoming fellowships. Fellows will be offered an independent and personalized scientific training choosing from two specific scientific domains: Digital Sciences and Conservation, within the specific panels of Digital Sciences, Physical Sciences, Basic and Natural Sciences, Environmental Sciences They will be enrolled in the T4C PhD programme and will be supervised by a joint supervision of academic and non-academic supervisors. Fellows will attend an exclusive traninig programme, encompassing basic traninig, scientific training through individual project implementation and interdisciplinary training, short term visits, secondment opportunities at non-academic premises, soft skills, dissemination and outreach activities. T4C intends also to capitalize on the experience of the already funded Cofund project (Train2Move) in managing international mobility programmes with national and international impact and in aligning national mechanisms to EU ones.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2016 - Co-funding of regional, national and international programmes"], "Funding_scheme": ["MSCA-COFUND-DP - Doctoral programmes"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["754511"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2016"]}, -{"Partners": ["UNIVERSITEIT ANTWERPEN"], "EU_Contribution": ["EUR 160 800"], "Project_Title": ["CAD WALK: Enabling Computer Aided Diagnosis of Foot Pathologies through the use of Metric Learning"], "Total_Cost": ["EUR 160 800"], "Country": ["Belgium"], "Project_ACR": ["CAD WALK"], "Technology_Description": "Dynamic plantar pressure imaging (PPI) refers to the measuring, across time, of pressure fields between the foot and the ground. PPI is used, in part, to diagnose foot problems such as metatarsalgia and plantar fasciitis. Despite the widespread clinical use of PPI, its diagnostic potential has not been fully exploited. PPI creates large and dynamic datasets that cannot be easily analysed and interpreted by the human brain. As a result, PPI images are subsampled before being clinically examined, which discards potentially valuable information.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["746614"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE DE FRIBOURG"], "EU_Contribution": ["EUR 187 419,60"], "Project_Title": ["Bio-inspired helicoidal multilayers for photonic innovation"], "Total_Cost": ["EUR 187 419,60"], "Country": ["Switzerland"], "Project_ACR": ["HELICOID"], "Technology_Description": "Natural photonic structures are present in a wide variety of flora and fauna, and are useful for camouflage mechanisms, mating and pollination signalling among other biological purposes. These natural photonic architectures constitute an invaluable source of blueprints for scientists to innovate in bio-inspired technological devices that can make a real impact in the technology based economy, for example in sensors, solar cells and lighting applications. Among the natural structures that have an artificial counterpart with huge impact in the economy are optical thin films, where for example single layers are used for anti-reflection coatings and multilayers for high quality mirrors and filters. Interestingly, some animals, such as the scarab beetles, exhibit unique circular polarization dependent reflection properties due to an inner helicoidal structure embedded within the multilayers of its cuticle. Fabricating such multilayers with added optical functionalities can find applications for example in anti-counterfeiting elements or in optical applications as chirality dependent micro-mirrors. During this MSCA I aim to gain the necessary training and knowledge to become an independent researcher in the fields of structural colour in nature and bio-inspired photonic devices. To achieve this goal, I will build up from the expertise of the host supervisor (Prof. Ullrich Steiner) and his group at the Adolphe Merkle Institute in Fribourg, Switzerland on the field of structural colour in nature, and specifically, on their experience with the chiral structures of such beetles. I will investigate novel multilayered devices exhibiting unique optical properties by performing optical simulations and combining state-of-the-art nano-patterning techniques together with a self-assembly method for multilayer fabrication that will yield unprecedented optical responses leading to innovative photonic devices.", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["741855"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE DE STRASBOURG"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Vibrational Polariton Nonlinear Optics and Chemistry"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["PlaN"], "Technology_Description": "The strong coupling of a quantum state to a cavity light field has just recently revealed many fascinating effects: Chemical reactions have been dramatically slowed down and nonlinear effects have been enhanced by orders of magnitude. These findings motivate to significantly extend the research on this novel type of light-hybridized matter. The objective of this proposal is to investigate dynamics and structural properties of molecules under vibrational strong coupling for the first time by virtue of mid-infrared femtosecond light pulses. The proposed studies will lead to a significant advancement of the research field with respect to the fundamental understanding of strong coupling induced modifications of matter and applications of vibrational strong coupling in photonics as well as chemistry. ", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["753228"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["QUEEN MARY UNIVERSITY OF LONDON"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Investigation of the role and mechanism of action of NOD2-mediated isoform selective PI3K signalling in gut immunity and inflammation"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["Signalling-in-NODs"], "Technology_Description": "Inflammatory bowel disease (IBD) is a complex chronic pathology in western societies. There is an unmet need for new therapeutic strategies which can only be achieved through a better understanding of the molecular mechanisms of host immunity. It is established that dysregulated host innate immune recognition either caused by genetic risk variants in pathogen recognition receptor (PRR) molecules or microbial factors is commonly associated with IBD. A unique PRR family member, Nucleotide oligomerization domain (NOD)2 programs gut immunity and protection through autophagy process initiated by the recognition of microbial peptides. Deleterious mutations in NOD2 and autophagy-associated proteins are linked to IBD susceptibility. Despite the advances made in understanding of the mechanisms underlying NOD2 biology, particularly that of autophagy, very little is known about the cell signaling components and their mechanism regulating autophagy under NOD2 pathway. Recently, I discovered that a single Phosphoinositide 3-kinases (PI3K) isoform p110\u03b4 is integrated in NOD2 mediated autophagy process. PI3Ks are an evolutionarily conserved family of signaling molecules that integrate PRR signaling. PI3Ks generate lipid second messengers and regulate mediated immune responses. I now propose to unravel key biological phenomenon by which p110\u03b4 PI3K convey host protective functions through NOD2-mediated autophagy, ensuring the gut immunity and tolerance. The aims are to (1) Determine the dendritic cell-intrinsic role and mechanism(s) of action of PI3K isoforms in orchestrating anti-inflammatory processes under NOD2-mediated autophagy. (2) Discover the roles of PI3K isoforms in NLR-mediated intestinal immunity using isoform specific PI3K gene-targeted mice alongside with pharmacological targeting strategies in vivo. My plan is integrated with animal models, immunology, cell biology, microbiology and in vivo inflammation studies to elucidate key biological phenomena driving IBD.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["753567"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF WOLVERHAMPTON"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Governance and value-creation in SMEs in a service-dominant logic"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["GoSMEs"], "Technology_Description": "Small and medium-sized enterprises (SMEs) form the backbone of the European economies in terms of employment, job creation, innovation and ability to add economic value. Because of that, SMEs have received much attention from scholars seeking to understand determinants of their competitiveness as well as from policy-makers at national and European levels aiming to provide support measures to facilitate their growth. It is well understood that SMEs command fewer resources and are more volatile than their large counterparts, and therefore need to pursue different trajectories to compete. What is less well known is whether and how SMEs harness the potential of their boards of directors to improve value-creation thus strengthening their competitiveness. This fellowship aims to advance knowledge by investigating how boards in SMEs contribute to value-creation within a service-dominant logic, taking into account the heterogeneity of SMEs as well as country-specific factors. By bringing together perspectives from multiple disciplines such as strategic management, marketing, organisational behaviour and psychology, and adopting a mixed methods research design that is close to and captures the complexity of the phenomenon, the results from the project will generate novel yet rigorous insights into the strategic dimensions of SME governance. A set of carefully designed user engagement and outreach activities will ensure that this new knowledge is transmitted into practice and available to a wider public audience. With the help of subject-related, methodological, and professional training and secondments, this fellowship provides a unique opportunity for Dr Yar Hamidi to advance his knowledge in a subject area he is passionate about as well as creating a sound platform from which to develop his scholarly career.", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["748905"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["OSPEDALE SAN RAFFAELE SRL"], "EU_Contribution": ["EUR 168 277,20"], "Project_Title": ["Triggering Haematological Adoptive T-cell Immunotherapy Strategies by HUnting Novel T-cellreceptors"], "Total_Cost": ["EUR 168 277,20"], "Country": ["Italy"], "Project_ACR": ["THAT IS HUNT"], "Technology_Description": "Recent encouraging clinical results obtained with engineered T lymphocytes and increasing advances in the genome editing field, have opened new opportunities for T-cell receptor (TCR) gene therapy as an immunotherapeutic approach for cancer.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-SE - Society and Enterprise panel"], "Coordinated_in": ["Italy"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-01-01"], "Project_ID": ["752717"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FREIE UNIVERSITAET BERLIN"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Between Evidence and Representation: History of Performance Art Documentation from 1970 to 1977"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["HiPArtDoc"], "Technology_Description": "\"Between Evidence and Representation: History of Performance Art Documentation from 1970 to 1977\" introduces a new historiographical approach that accounts for the dynamic development of performance art and its theories through the history of performance documentation. Focussing on the role of performance documentation in the conservation and presentation of performance-based art from 1970 to 1977, \u201cBetween Evidence and Representation\u201d will examine the different strategies undertaken to provide duration and mediated access to definitionally ephemeral and immaterial events. The project\u2019s aim is to demonstrate that, simultaneous to the formation, circulation, and acknowledgment of the category of performance art in the early 1970s, performance documentation itself was aestheticised. The goal of the research is to show that both these changes are part of an historical process of containment of performance within the traditional framework of visual arts. Thereby, \u201cBetween Evidence and Representation\u201d will show how this process actively shaped the history of performance art, filling a gap in the historiography of performance art and performance documentation. The research programme, which will end in the publication of a monograph, will be carried out in three phases. In the first phase, programmatic writings by artists and art movements will be used to map theories of performance from the 1950s to the 1970s. Referencing art journals, indexes, and exhibitions catalogues and documents, the second phase will examine the function assigned to performance documentation from 1970 to 1977, as well as its correlation to parallel developments in the critical discourse concerning the medium of \u201cperformance\u201d. The last phase of the research, relying on archival sources, will provide a final corroboration to the research hypothesis through its application to four paradigmatic case studies.\"", "To": ["2019-05-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-29"], "Project_ID": ["747881"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITEIT ANTWERPEN"], "EU_Contribution": ["EUR 160 800"], "Project_Title": ["Novel Atg4B-inhibitors and dual [Atg4B-carbonic anhydrase]inhibitors for interfering with cytoprotective mechanisms of cancercells in the acidic tumor micro-environment."], "Total_Cost": ["EUR 160 800"], "Country": ["Belgium"], "Project_ACR": ["ONCOPHAGY"], "Technology_Description": "The microenvironment of most solid tumors tends to be significantly more acidic than healthy tissue. Inadequate perfusion, oxygen limitation and cell metabolic changes, are key causative factors for this situation. The acidic pH induces a number of specific genetic, transcriptional and metabolic effects in tumor cells. These are required for survival under increased H+-stress. Evidence is now mounting that these effects also play a major role in tumor progression, invasiveness and the development of multi-resistance to therapy. Two pivotal adaptations related to maintaining intracellular pH homeostasis in an acidic environment, have recently received significant attention: (1) the presence of chronic autophagy in tumors and (2) the overexpression of carbonic anhydrases (CAs), mainly CA IX and CA XII. ", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["753221"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["The limits of the sciences in identifying causes and scientific laws"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["Alexander Krauss"], "Technology_Description": "Scientists rarely question the scientific methods \u2013 and their related complex theory, strong assumptions and problematic quantitative techniques \u2013 used to generate the causes and laws in their particular scientific models, which is the guiding research question of this project. Better understanding the limits of using mathematical and statistical methods in science is important for research and policy, because these methods all lead to some degree of biased results and scientists using them often misguidedly claim to establish strong causal relationships. This research project will investigate the underlying assumptions of quantitative methods by critically assessing the leading, most cited academic studies across the sciences that all use some form of mathematical and statistical methods. By combining theoretical, methodological and empirical analysis, this research project will help disentangle the links between the actual methods applied by scientists and the causal effects and scientific laws they claim to identify in their models. Identified causes and laws need to always be understood in the context of the different methods used to express them. This research project thus aims to address the gaps in the literature on scientific methodology by providing insight and knowledge into the large set of important assumptions and limitations behind mathematical and statistical methods used to identify causes and scientific laws. By helping to increase awareness among scientists about these biases and constraints and by outlining ways to better combine multiple methods, this project also aims to help improve scientific practice. More broadly, it hopes to help improve how we understand scientific methodology and thus science and evidence-based policymaking.", "To": ["2019-03-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-03-15"], "Project_ID": ["745447"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FREIE UNIVERSITAET BERLIN"], "EU_Contribution": ["EUR 243 352,80"], "Project_Title": ["In Defence of Experimental Medicine: Emotional Appeals and Medical Didacticism in Germany,Britain and North America, 1870-1914"], "Total_Cost": ["EUR 243 352,80"], "Country": ["Germany"], "Project_ACR": ["IDEM"], "Technology_Description": "IDEM analyses the didactic strategies of the medical establishment in Germany, the UK and North America in educating the public about the benefits of experimental medicine. The period of focus is from 1870 to 1914: the key expansion phase for experimental medicine in physiology, toxicology, surgery and immunology. Educational strategies were important for ensuring the on-going freedom of medical research in the face of opposition from the lay public on ethical, moral and aesthetic grounds. Potential legal checks on medical practice motivated doctors to change anti-scientific opinion through informal educational strategies, involving the dissemination of knowledge, the disparagement of opponents of experimentation, and influence over popular emotional reactions to medical science. IDEM probes the internal politics of the medical establishments of each area and the ways in which they learnt from each other through networks of exchange and experience. IDEM\u2019s objectives are: 1. To explore the pedagogical techniques and strategies of the medical establishment in their efforts to \u201csell\u201d experimental medicine to the lay public, in England, Germany and North America, c. 1870-1914. 2. To reveal the ways in which these techniques and strategies involved transnational networks and exchanges among these countries that worked to represent an orthodoxy of medical endeavour. 3. To interpret how far medical didacticism in this period depended upon affective appeals, either instead of or embedded into the dissemination of medical knowledge, and the extent to which such appeals were gendered. 4. To analyse the extent to which the defence of medical experimentation transformed both medical institutions and medical personalities into a) political agents and b) public bodies. 5. To assess the extent to which affective didacticism sought to change the emotional responses of both the public and of medical practitioners to the sights, practices and results of experimental medicine.", "To": ["2020-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["742470"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["JYVASKYLAN YLIOPISTO", "Teknologian tutkimuskeskus VTT Oy", "TAMPEREEN YLIOPISTO", "OULUN YLIOPISTO", "LAPIN YLIOPISTO", "Tiedekeskuss\u00e4\u00e4ti\u00f6", "Federation of Finnish Learned Societies", "HELSINGIN YLIOPISTO", "TURUN YLIOPISTO", "ITA-SUOMEN YLIOPISTO", "TTY-SAATIO"], "EU_Contribution": ["EUR 233 584,50"], "Project_Title": ["Researchers Changing Society"], "Total_Cost": ["EUR 428 884,25"], "Country": ["Finland", "Finland", "Finland", "Finland", "Finland", "Finland", "Finland", "Finland", "Finland", "Finland", "Finland"], "Project_ACR": ["CHANGE"], "Technology_Description": "The CHANGE project aims to foster collaboration between the public and researchers in Finland in order to improve our everyday life in a rapidly changing world. This project brings together 9 universities, 1 research institute and two expert organisations for science communication. It spans many facets of research in Finland and covers numerous individual researchers with diverse backgrounds and research topics. We will deliver a message of cutting edge research conducted in Finland and introduce the general public with the large number of researchers and the significant work they perform. We want to break stereotypes the general public may have on researchers. The programme for activities during the night will include content for everyone, from children to seniors. However, the specific aim is to promote research careers especially to high school and university students, and young people in general who are about to make their first real career choice. Our message is that high education is fun and could provide them with a secured future. For the first time, so many Finnish universities and organisations will unite for a widespread European Researchers\u2019 Night and perform simultaneously activities targeted for the general public around the country.", "To": ["2017-12-31, closed project |"], "Meta": [""], "Topic_s": ["MSCA-NIGHT-2016 - European Researchers' Night"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["722854"], "Call_for_Proposal": ["H2020-MSCA-NIGHT-2016"]}, -{"Partners": ["FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG", "FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG"], "EU_Contribution": ["EUR 2 491 250"], "Project_Title": ["Exploration of the 2D-Chemistry of Black Phosphorous"], "Total_Cost": ["EUR 2 491 250"], "Country": ["Germany", "Germany"], "Project_ACR": ["B-PhosphoChem"], "Technology_Description": "We propose the development of the chemistry of black phosphorus (BP). B-PhosphoChem will constitute a new text book chapter in the realm of synthetic chemistry located at the interface of inorganic-, organic-, and materials chemistry as well as solid state physics. B-PhosphoChem will provide the basis for exciting and so far elusive applications such as ion batteries and stable high performance devices. Thin sheets of BP represent a new class of 2D materials and have recently raised tremendous interest in the scientific community. Outstanding physical properties such as high charge carrier mobility, combined with transparency and the persistence of a band gap have been discovered. However, the chemistry of BP remains still unexplored. B-PhosphoChem will close this gap and will a) provide the opportunity to modulate and fine tune the physical properties, b) allow for considerably improving the processability and increasing the solubility, c) establish concepts for the desired chemical stabilization, d) give access to the combination of BP properties with those of other compound classes, e) reveal the fundamental chemical properties and reactivity principles, and f) provide methods for establishing practical applications. Five work packages will be addressed: 1) Production of Thin Layer BP, 2) Supramolecular Chemistry of BP, 3) Intercalation Compounds of BP, 4) Covalent Chemistry of BP, and 5) BP-Based Materials and Devices. The work packages will be supported by systematic calculations. For our group, whose core competence is synthetic organic and supramolecular chemistry, the orientation towards inorganic phosphorus chemistry constitutes a major step into a completely new direction. However, we are convinced to be the most predestinated research group in the world successfully facing this challenge because of our leadership and well documented interdisciplinary experience in synthesizing and characterizing 0D-, 1D-, and 2D nanostructures.", "To": ["2022-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["742145"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["INSTYTUT CHEMII FIZYCZNEJ POLSKIEJ AKADEMII NAUK", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "ECOLE NATIONALE SUPERIEURE DE CHIMIE DE PARIS", "INSTITUTE FOR CONDENSED MATTER PHYSICS OF THE NATIONAL ACADEMY OF SCIENCES OF UKRAINE", "UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6"], "EU_Contribution": ["EUR 684 000"], "Project_Title": ["Effects of confinement on inhomogeneous systems"], "Total_Cost": ["EUR 684 000"], "Country": ["Poland", "Spain", "France", "Ukraine", "France"], "Project_ACR": ["CONIN"], "Technology_Description": "The objective of the project is determination of universal features and specific properties of various systems spontaneously ordering into spatially inhomogeneous structures (mobile ions in solids, ionic liquid mixtures, soft-matter and biological systems), with special focus on effects of confinement. There is striking similarity between properties of the above systems despite different interactions and length scales of inhomogeneities. The fundamental relation between structural inhomogeneities and mechanical and thermodynamic properties is not fully understood because the exchange of knowledge between the solid-state, liquid-matter, soft-matter and biophysical communities is limited. Theoretical and simulation approaches developed by 3 EU MS + 1 AC + 2 TC groups are closely connected or complementary. We use mean-field, liquid-matter, DFT, integral equations, field and collective-variables theories, molecular simulation approaches, and experimental methods of electrochemistry. We will share our experience in constructing/modifying, solving and verifying experimentally models for different complex systems. The new results and theoretical approaches will help in future studies of various inhomogeneous systems. The first work package concerns systems spontaneously forming ordered patterns, from thin films on solid surfaces through particles on interfaces to biological membranes and arid ecosystems. The pattern formation can be exploited in innovative technology. In the second work package we will investigate ionic liquids/ionic-liquid mixtures, especially near charged surfaces and in porous media, and mobile ions in intercalation compounds. Mobile ions and ionic liquids in porous electrodes are potentially important in innovative electrochemistry. EU/TC knowledge transfer will be by joint theoretical, simulation and experimental studies. Open workshops will be organized. Long term visits of young researchers and joint supervision of PhD students are planned.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Poland"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["734276"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["UNIVERSIDAD PABLO DE OLAVIDE", "UNIVERSIDAD PABLO DE OLAVIDE"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Targeting infertility associated to defective Insulin/IGF-1 signalling"], "Total_Cost": ["EUR 150 000"], "Country": ["Spain", "Spain"], "Project_ACR": ["INFISS"], "Technology_Description": "Fertility decline is the largest contributor to population ageing in the world today, and infertility negatively impacts on the mental a social wellness of the population affected. One of the causes of birth rate tumbling is the trend of later motherhood in modern societies and the infertility associated to diabetes and polycystic ovary syndrome (PCOS). PCOS is the leading cause for ovulatory infertility, being the most common endocrine and metabolic disorder, affecting women in reproductive age. Women suffering from diabetes frequently suffer from infertility and PCOS, while two-thirds of adult women with PCOS suffer from insulin resistance and hyperinsulinemia. The ERC-StG MitoSigAge funds research directed to understand the process of ageing with a focus on insulin/IGF-1 signalling (IIS) and its interaction with mitochondrial metabolism. PCOS blocks oocyte maturation and ovulation, suggesting a tight link between mitochondrial energy metabolism and oocyte development mediated by IIS. One of the applications emanating from this research lies in the identification of molecular targets to combat diabetes-associated sterility. The objective of the ERC-PoC is four-fold: First, identify evolutionarily conserved molecular targets that, when inactivated, suppress sterility associated to defective IIS. Second, identify existing drugs for the identified targets and ascertain which compounds have the best therapeutic potential. Third, perform the necessary patenting of the compounds for this new application and the initial steps towards the valorisation of the identified products and their commercial potential. Fourth, market studies to evaluate the commercial potential of our technology. These steps will bridge a scientific idea from basic research to therapeutic applications. If successful, it will provide important societal and economical benefits, helping combating the downsides associated to our modern ageing society.", "To": ["2018-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["737559"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["TECHNISCHE UNIVERSITEIT EINDHOVEN", "TECHNISCHE UNIVERSITEIT EINDHOVEN"], "EU_Contribution": ["EUR 149 750"], "Project_Title": ["Therapeutic antibody drug monitoring using bioluminescent sensors proteins and a smartphone"], "Total_Cost": ["EUR 149 750"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["LUMABS"], "Technology_Description": "Therapeutic antibodies represent an important class of newly introduced drugs and have been particularly successful in cancer therapy and the treatment of inflammatory diseases. The clearance rates of therapeutic antibodies are known to differ per individual and correlate with survival rates. Being able to define a personalized dose per patient based on continuous monitoring of therapeutic antibody levels would therefore be beneficial both for the individual patient and for the hospital\u2019s budget. Our group recently developed a new platform of bioluminescent sensor proteins for antibody detection that allow antibody detection directly in blood plasma using the camera of a smart phone as the sole piece of equipment. ", "To": ["2018-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["755471"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["UNIVERSIDAD POMPEU FABRA", "UNIVERSIDAD POMPEU FABRA"], "EU_Contribution": ["EUR 1 381 250"], "Project_Title": ["Global Production Networks and Macroeconomic Interdependence"], "Total_Cost": ["EUR 1 381 250"], "Country": ["Spain", "Spain"], "Project_ACR": ["GLOBALMACRO"], "Technology_Description": "Researchers and policymakers alike have highlighted the potential efficiency gains of a global production structure. However, such linkages also raise the possibility of risks. This proposal tackles both empirical and theoretical challenges in incorporating the microeconomic structure of trade and international production networks in the study of the propagation of shocks internationally, and their impact on macroeconomic interdependence. Using newly constructed micro-level datasets, I provide quantitative analysis of the importance of the linkages in multicountry general equilibrium models of trade. First, using firm export and imported-input linkages, I provide a novel model-based estimation strategy to identify the role of country and firm-level shocks, and the implications of these estimates for the transmission of shocks across borders. By using structural trade models to estimate shocks at the firm level and studying the implications for the transmission of shocks across borders, I help bridge the micro-macro nexus in international economics. Second, I take an even more granular focus by studying the role of firm-to-firm production linkages in transmitting shocks across countries. To do so, I exploit a novel matching procedure between a country\u2019s administrative dataset and cross-country firm-level data. I further build on these data by adding in domestic bank-firm relationships. This strategy allows for the study of how financial shocks are exported abroad via firms\u2019 trade and multinational linkages. Third, I incorporate the insights from the empirical work into a full-scale multicountry general equilibrium model of trade, which allows for firm-level heterogeneity and microeconomic and macroeconomics shocks. I use the model for a quantitative study of the cross-country transmission of the different shocks via trade. This allows me to perform counterfactuals and examine the impact of policies, such as how opening to trade impacts macroeconomic interdependence.", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["726168"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI TRIESTE", "CARDIFF UNIVERSITY", "CONSIGLIO NAZIONALE DELLE RICERCHE", "NOVA ID FCT - ASSOCIACAO PARA A INOVACAO E DESENVOLVIMENTO DA FCT", "YD YNVISIBLE SA", "MEDITEKNOLOGY SRL", "A.P.E. RESEARCH SRL", "UNIVERSITE DE NAMUR ASBL"], "EU_Contribution": ["EUR 1 237 500"], "Project_Title": ["Engineering optoelectronic INterfaces: a global action intersecting FUndamental conceptS and technology implementatION of self-organized organic materials"], "Total_Cost": ["EUR 1 237 500"], "Country": ["Italy", "United Kingdom", "Italy", "Portugal", "Portugal", "Italy", "Italy", "Belgium"], "Project_ACR": ["INFUSION"], "Technology_Description": "Investing in energy efficiency and saving is crucial to support energy accessibility and environmental protection, and it is the world\u2019s best interest to share and implement forms of energy efficiency. This implies a stronger and effective transnational policy to promote and disseminate know-how about new technologies both at the market and R&D level. In this respect, development of projects centered on energy efficient technologies based on nanostructured organic materials certainly is a strategic field. The progresses in mastering organic matter by self-assembly and self-organization to form ordered soft-materials revolutionized the field opening new frontiers for both fundamental and applied research. However the route towards organic materials for application at the industrial scale is restricted by difficulties in the control and manipulation of the structural organization at the molecular level and its manifestation at higher scales. Motivated by the potential for significant energy savings, the INFUSION project aims to create a strongly interdisciplinary and inter-sectorial environment in which the principles of self-organization are poured from the Academia into the private sector and vice-versa to create new paradigms to engineer electrochromic devices. Through a detailed plan of 83 secondments, the project aims at cross-fertilize the electrochromic technology joining specific expertise to realize a bottom-up approach toward the design, preparation and characterization of self-organized organic materials (chromophores, CNSs, polymers...) at different interfaces (ITO, graphene) and exhibiting superior performances (optical, durability\u2026). For the transfer of knowledge, the project combines the multidisciplinary expertise of 6 universities, 1 research institute, and 3 companies representing 4 EU and 2 TC countries (Pakistan and Argentina) in the field of organic chemistry, photochemistry, surface science, polymer and materials science, and device engineering.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["734834"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS", "FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS"], "EU_Contribution": ["EUR 1 999 832"], "Project_Title": ["Pyrogenic TRansformations Affecting Climate and Health"], "Total_Cost": ["EUR 1 999 832"], "Country": ["Greece", "Greece"], "Project_ACR": ["PyroTRACH"], "Technology_Description": "Biomass burning (BB) is a significant contributor to global atmospheric particulate matter, with strong impacts on climate, ecosystems and public health. Yet these impacts are highly uncertain, largely owing to our inability to track BB particulate matter and the evolution of their properties throughout most of its atmospheric lifetime. PyroTRACH will provide the necessary breakthroughs in our understanding of BB particles and their impacts by: i) deriving new markers of biomass burning with an atmospheric lifetime that exceeds the current limitation of about a day, ii) measuring highly uncertain but critically-important climate- and health- relevant properties of aerosols both from wildfire events that occur during summertime and from BB for heating purposes during wintertime in highly populated urban environments, iii) applying this new knowledge to quantify the contribution of biomass burning to aerosol in the Mediterranean region, and quantify its impacts on climate and public health. Novel state-of-the-art instrumentation, portable environmental chambers and well established measurement techniques will be applied in continuous measurements as well as intensive field campaigns to study the properties and evolution of BB particulates as they age in the atmosphere. Discovering new stable chemical markers that allow detection of BBOA many days after emission, while carefully and accurately following the climate and health-related properties of freshly emitted and aged BBOA, allows for an unprecedented understanding of the evolution and impacts of biomass burning aerosol and its impact on the Earth System and public health. Considering the increasing occurrence of wildfires, along with decreased emissions from fossil fuels means that accurately predicting the health and climate effects from biomass burning aerosol is one of the most important aspects of atmospheric aerosol that needs to be studied.", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Greece"], "Activity": ["Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555", "Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555"], "From": ["2017-06-01"], "Project_ID": ["726165"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["COPENHAGEN BUSINESS SCHOOL", "COPENHAGEN BUSINESS SCHOOL"], "EU_Contribution": ["EUR 1 590 036"], "Project_Title": ["Algorithmic Finance: Inquiring into the Reshaping of Financial Markets"], "Total_Cost": ["EUR 1 590 036"], "Country": ["Denmark", "Denmark"], "Project_ACR": ["AlgoFinance"], "Technology_Description": "Present-day financial markets are turning algorithmic, as market orders are increasingly being executed by fully automated computer algorithms, without any direct human intervention. Although algorithmic finance seems to fundamentally reshape the central dynamics in financial markets, and even though it prompts core sociological questions, it has not yet received any systematic attention. In a pioneering contribution to economic sociology and social studies of finance, ALGOFINANCE aims to understand how and with what consequences the turn to algorithms is changing financial markets. The overall concept and central contributions of ALGOFINANCE are the following: (1) on an intra-firm level, the project examines how the shift to algorithmic finance reshapes the ways in which trading firms operate, and does so by systematically and empirically investigating the reconfiguration of organizational structures and employee subjectivity; (2) on an inter-algorithmic level, it offers a ground-breaking methodology (agent-based modelling informed by qualitative data) to grasp how trading algorithms interact with one another in a fully digital space; and (3) on the level of market sociality, it proposes a novel theorization of how intra-firm and inter-algorithmic dynamics can be conceived of as introducing a particular form of sociality that is characteristic to algorithmic finance: a form of sociality-as-association heuristically analyzed as imitation. None of these three levels have received systematic attention in the state-of-the-art literature. Addressing them will significantly advance the understanding of present-day algorithmic finance in economic sociology. By contributing novel empirical, methodological, and theoretical understandings of the functioning and consequences of algorithms, ALGOFINANCE will pave the way for other research into digital sociology and the broader algorithmization of society.", "To": ["2021-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["725706"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["KING'S COLLEGE LONDON", "KING'S COLLEGE LONDON"], "EU_Contribution": ["EUR 2 318 719"], "Project_Title": ["FOG-aided wireless networks for communication, cacHing and cOmputing: theoRetical and algorithmic fouNdations"], "Total_Cost": ["EUR 2 318 719"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["FOGHORN"], "Technology_Description": "\"The FOGHORN project aims at developing the theoretical and algorithmic foundations of fog-aided wireless networks. This is an emerging class of wireless systems that leverages the synergy and complementarity of cloudification and edge processing, two key technologies in the evolution towards 5G systems and beyond. Fog-aided wireless networks can reap the benefits of centralization via cloud processing, in terms of capital and operating cost reductions, greening, and enhanced spectral e fficiency, while, at the same time, being able to cater to low-latency applications, such as the \"tactile\" internet, by means of localized intelligence at the network edge. The operation of fog-aided wireless networks poses novel fundamental research problems pertaining to the optimal management of the communication, caching and computing resources at the cloud and at the edge, as well as to the transmission on the fronthaul network connecting cloud and edge. The solution of these problems challenges the theoretical principles and engineering insights which have underpinned the design of existing networks. The initial research activity on the topic, of which the EU is at the forefront, focuses, by and large, on ad hoc solutions and technologies. In contrast, the goal of this project is to develop fundamental theoretical insights and algorithmic principles with the main aim of guiding engineering choices, unlocking new academic opportunities and disclosing new technologies. The theoretical framework is grounded in network information theory, which enables the distillation of design principles, along with signal processing, (non-convex) optimization, queuing and distributed computing to develop and analyse algorithmic solutions.\"", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["725731"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG", "FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 996 570"], "Project_Title": ["Microscopic Origins of Fracture Toughness"], "Total_Cost": ["EUR 1 996 570"], "Country": ["Germany", "Germany", "France"], "Project_ACR": ["microKIc"], "Technology_Description": "The resistance to crack propagation is undoubtedly one of the most important properties of structural materials. However, our current mechanistic understanding of the fracture processes in typical semi-brittle materials like steels, refractory metals or semiconductors is not sufficiently advanced to predict the fracture toughness KIc and its dependence on the microstructure, temperature and strain rate. Therefore, KIc is commonly regarded as a phenomenological material parameter for fracture mechanics models that require experimental calibration. ", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2017-05-01"], "Project_ID": ["725483"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER", "WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER"], "EU_Contribution": ["EUR 1 989 812,50"], "Project_Title": ["Photonic integrated quantum transceivers"], "Total_Cost": ["EUR 1 989 812,50"], "Country": ["Germany", "Germany"], "Project_ACR": ["PINQS"], "Technology_Description": "Quantum processors are envisioned to conquer ultimate challenges in information processing and to enable simulations of complex physical processes that are intractable with classical computers. Among the various experimental approaches to implement such devices, scalable technologies are particularly promising because they allow for the realization of large numbers of quantum components in circuit form. For upscaling towards functional applications distributed systems will be needed to overcome stringent limitations in quantum control, provided that high-bandwidth quantum links can be established between the individual nodes. For this purpose the use of single photons is especially attractive due to compatibility with existing fibre-optical infrastructure. However, their use in replicable, integrated optical circuits remains largely unexplored for non-classical applications.", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["724707"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["PARIS-LODRON-UNIVERSITAT SALZBURG", "PARIS-LODRON-UNIVERSITAT SALZBURG"], "EU_Contribution": ["EUR 1 705 833"], "Project_Title": ["Power in international trade negotiations"], "Total_Cost": ["EUR 1 705 833"], "Country": ["Austria", "Austria"], "Project_ACR": ["TRADEPOWER"], "Technology_Description": "For the last twenty years, countries across the globe have negotiated a large number of preferential trade agreements. In parallel, trade negotiations have taken place in the framework of the World Trade Organization. These negotiations not only deal with tariffs, but also cover investments, competition policy, labour standards and much more. With much at stake, the extent to which different countries are able to achieve their preferred outcomes in these negotiations is of broad interest. In this project, I address this topic by asking: what makes some countries have more bargaining power than others in these negotiations? In other words, what explains variation in bargaining power in trade negotiations? ", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["724107"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY", "TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Hydrogen production by membrane free chemical \u2013 electrochemical systems"], "Total_Cost": ["EUR 150 000"], "Country": ["Israel", "Israel"], "Project_ACR": ["HYMEFCECS"], "Technology_Description": "Until recently it was believed to be impossible to produce hydrogen through water electrolysis systems, without an electrochemical oxygen production process and without a membrane. However, in the past few years, our team was able to develop a new technological configuration which divides the water splitting process into two phases : (1) an efficient electrochemical hydrogen production followed by a (2) spontaneous chemical oxygen production phase. By eliminating the inefficient electrochemical water oxidation reaction (OER) we achieve a significant increase in hydrogen production efficiency. Furthermore, reducing the danger of mixing hydrogen and oxygen eliminates the need for a membrane. A membrane-free system enables high pressure hydrogen production without the risk of gas mixture or membrane failure. Moreover, as the membrane failure is the main cause for malfunctions and offline times of alkaline and PEM electrolyzer, our technology improves system reliability and energy efficiency.", "To": ["2018-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["727606"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["FUNDACION CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III", "FUNDACION CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III"], "EU_Contribution": ["EUR 1 995 000"], "Project_Title": ["Functional characterisation of mitochondrial metabolic adaptations to innate sensing in dendritic cell subsets"], "Total_Cost": ["EUR 1 995 000"], "Country": ["Spain", "Spain"], "Project_ACR": ["MITOMAD"], "Technology_Description": "Immunometabolism is an emerging research field that promises to generate novel targets for manipulation of functional responses in immune cells. Pioneering studies are beginning to unveil how innate sensing leads to metabolic reprogramming of immune cells. We became interested in the possible metabolic consequences of innate sensing by myeloid cells because of our previous work showing how mouse and human dendritic cell (DC) subsets detect danger signals from microbes and damaged tissues. Our current data show that sensing of live bacteria triggers a profound reorganisation of the mitochondrial electron transport chain (ETC) in macrophages, with a switch in the relative contribution of ETC complexes I and II to mitochondrial respiration that impacts immune response. As we pursue novel strategies to manipulate DC function, and supported by our preliminary data in DCs, we hypothesise that innate sensing induces mitochondrial adaptations in DCs and that targeting mitochondrial metabolism will affect DC function. Our goals are: 1) to characterise how innate sensing of danger signals from microbes or from tissue damage modulate mitochondrial adaptations and metabolic reprogramming in mouse and human DC subsets; 2) to dissect the molecular mechanisms that connect innate sensing and mitochondrial adaptations in DCs, using biased and unbiased cutting-edge proteomics approaches; 3) to address the impact of manipulating mitochondrial biology on mouse and human DC metabolism and function; and 4) to assess the functional in vivo effects of targeting mitochondrial biology in DCs in homeostasis and disease. The characterisation of the molecular mechanisms that link innate sensing and mitochondrial metabolism with DC function will open new avenues for basic research in mitochondrial biology and for the emerging field of immunometabolism. Functional targeting of DC mitochondrial metabolism has great potential for the discovery of new strategies to modulate immunity and tolerance.", "To": ["2022-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-12-01"], "Project_ID": ["725091"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITAET POTSDAM", "UNIVERSITAET POTSDAM", "LEIBNIZ - INSTITUT FUER PFLANZENGENETIK UND KULTURPFLANZENFORSCHUNG"], "EU_Contribution": ["EUR 1 998 525"], "Project_Title": ["The role of chromatin in the long-term adaptation of plants to abiotic stress"], "Total_Cost": ["EUR 1 998 525"], "Country": ["Germany", "Germany", "Germany"], "Project_ACR": ["CHROMADAPT"], "Technology_Description": "Abiotic stress is a major threat to global crop yields and this problem is likely to be exacerbated in the future. Therefore, it is very important to engineer crop plants with improved stress tolerance. A large body of research has focussed on the immediate stress responses. However, in nature stress is frequently chronic or recurring, suggesting that temporal dynamics are an important, but under-researched, component of plant stress responses. Indeed, plants can be primed by a stress exposure such that they respond more efficiently to the next stress incident. Such stress priming and memory may be particularly beneficial to plants due to their sessile life style. Typically, the memory of priming lasts for several days after the end of the stress. During the past few years, my group has initiated a molecular analysis of heat stress memory in Arabidopsis thaliana. Heat stress memory is associated with sustained gene induction and transcriptional memory and we have demonstrated that this involves lasting chromatin changes. The underlying molecular mechanisms, however, remain poorly understood. Here, I propose to combine mechanistic dissection of heat stress memory in A. thaliana with concomitant translation of the results into the temperate cereal crop barley. In particular, we will study the following questions: What is the role of chromatin during heat stress memory? How do the transcription factors involved mediate memory-specific outputs? How does nucleosome positioning affect heat stress memory? How do histone modifications during stress memory interact with transcription, chromatin and nuclear organization? Is heat stress memory conserved in temperate cereal species? Can we engineer plants with improved stress memory? Using existing tools and new methodologies, the proposed analyses will yield unprecedented insight into the long-term adaptation of plants to abiotic stress and open up approaches for breeding of stress-tolerant crops.", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2017-05-01"], "Project_ID": ["725295"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["BAYERISCHE JULIUS-MAXIMILIANS UNIVERSITAT WURZBURG", "BAYERISCHE JULIUS-MAXIMILIANS UNIVERSITAT WURZBURG"], "EU_Contribution": ["EUR 1 994 375"], "Project_Title": ["Herpesvirus Effectors of RNA synthesis, Processing, Export and Stability"], "Total_Cost": ["EUR 1 994 375"], "Country": ["Germany", "Germany"], "Project_ACR": ["HERPES"], "Technology_Description": "Herpes simplex virus 1 (HSV-1) is an important human pathogen, which intensively interacts with the cellular transcriptional machinery at multiple levels during lytic infection. Employing next-generation sequencing to study RNA synthesis, processing and translation in short intervals throughout lytic HSV-1 infection, my laboratory made the surprising observation that HSV-1 triggers widespread disruption of transcription termination of cellular but not viral genes. Transcription commonly extends for tens-of-thousands of nucleotides beyond poly(A)-sites and into downstream genes. In contrast to textbook knowledge, HSV-1 infection does not inhibit splicing but induces a broad range of aberrant splicing events associated with disruption of transcription termination. Exploring these fascinating phenomena will provide fundamental insights into RNA biology of human cells. ", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["721016"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 795 010"], "Project_Title": ["Nuclear envelope attachment and dynamics of Human telomeres - unravelling nuclear organization"], "Total_Cost": ["EUR 1 795 010"], "Country": ["France", "France"], "Project_ACR": ["TeloHOOK"], "Technology_Description": "The spatial and temporal organization of the nucleus and its components are essential for genome regulation. During interphase of mammalian cells the nuclear envelope maintains the shape and the mechanical integrity of the nucleus, but also provides an anchor for chromatin that is connected to its inner side. This interaction mediates the regulation of gene expression, DNA replication and the maintenance of genome stability. In human cells I found that a large subset of telomeres, the natural ends of linear chromosomes, are transiently anchored to the nuclear envelope specifically during postmitotic nuclear assembly. Chromatin organization undergoes extensive changes during progression through the cell cycle, particularly during mitosis with the nuclear envelope breakdown and the compaction of chromatin into metaphase chromosomes. The interaction between chromosome ends and the nuclear envelope at the stage where the nucleus is reforming post-mitosis suggests a new role for telomeres in nuclear organization. My aims are 1) to screen for interacting partners that mediate the cell-cycle dependent telomere tethering to the nuclear membrane; 2) to unravel the molecular mechanism of telomere-nuclear envelope association over the cell cycle by combining biochemistry and state-of-the-art microscopy; 3) to map the subset of chromosomes which ends are tethered using subtelomere specific FISH probes and determine whether they are conserved throughout cell divisions and if it plays a role in organizing chromosome territories; 4) to examine telomere dynamics in cells from premature aging syndromes affecting the nuclear envelope integrity using live imaging confocal microscopy, and understand the connection between telomeres, nuclear envelope, and aging. The originality of my scientific approach is to combine state-of-the-art cell biology, biochemistry, and molecular biology for an integrated view of human telomere function in nuclear organization.", "To": ["2022-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-11-01"], "Project_ID": ["714653"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM", "INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM"], "EU_Contribution": ["EUR 1 986 125"], "Project_Title": ["Applying silicon solar cell technology to revolutionize the design of thin-film solar cells and enhance their efficiency, cost and stability"], "Total_Cost": ["EUR 1 986 125"], "Country": ["Belgium", "Belgium"], "Project_ACR": ["Uniting PV"], "Technology_Description": "Thin film (TF) photovoltaics (PV) hold high potential for Building Integrated PV, an important market as European buildings require to be nearly zero-energy by 2020. Currently, Cu(In,Ga)(S,Se)2 (= CIGS(e)) TF solar cells have high efficiency, but also a simple one-dimensional cell design with stability and reliability concerns. Furthermore, its present research has been mainly focused on improving the absorber and buffer layers. ", "To": ["2022-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Belgium"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-03-01"], "Project_ID": ["715027"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["TECHNISCHE UNIVERSITEIT DELFT", "TECHNISCHE UNIVERSITEIT DELFT"], "EU_Contribution": ["EUR 1 998 750"], "Project_Title": ["New discrete choice theory for understanding moral decision making behaviour"], "Total_Cost": ["EUR 1 998 750"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["BEHAVE"], "Technology_Description": "Discrete choice theory provides a mathematically rigorous framework to analyse and predict choice behaviour. While many of the theory\u2019s key developments originate from the domain of transportation (mobility, travel behaviour), it is now widely used throughout the social sciences. ", "To": ["2022-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["724431"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["MEDIZINISCHE HOCHSCHULE HANNOVER", "MEDIZINISCHE HOCHSCHULE HANNOVER"], "EU_Contribution": ["EUR 1 499 750"], "Project_Title": ["Targeting the transcriptional landscape in infant AML"], "Total_Cost": ["EUR 1 499 750"], "Country": ["Germany", "Germany"], "Project_ACR": ["iAML-lncTARGET"], "Technology_Description": "Infant acute myeloid leukemia (AML) has a dismal prognosis, with a high prevalence of unfavorable features and increased susceptibility to therapy-related toxicities, highlighting the need for innovative treatment approaches. Despite the discovery of an enormous number and diversity of transcriptional products arising from the previously presumed wastelands of the non-protein-coding genome, our knowledge of non-coding RNAs is far from being incorporated into standards of AML diagnosis and treatment. I hypothesize that the highly developmental stage- and cell-specific expression of long non-coding RNAs shapes a chromatin and transcriptional landscape in fetal hematopoietic stem cells that renders them permissive towards transformation. I predict this landscape to synergize with particular oncogenes that are otherwise not oncogenic in adult cells, by providing a fertile transcriptional background for establishing and maintaining oncogenic programs. Therefore, the non-coding transcriptome, inherited from the fetal cell of origin, may reflect a previously unrecognized Achilles heel of infant AML, which I will identify with my expertise to understand and edit the AML genome and transcriptome.", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["714226"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["FREIE UNIVERSITAET BERLIN", "FREIE UNIVERSITAET BERLIN"], "EU_Contribution": ["EUR 1 489 919"], "Project_Title": ["Emotional Machines:The Technological Transformation of Intimacy in Japan"], "Total_Cost": ["EUR 1 489 919"], "Country": ["Germany", "Germany"], "Project_ACR": ["EMTECH"], "Technology_Description": "EMTECH analyzes the relationship between aesthetic works on human-robot interaction in Japan and cutting-edge advances in robotics and artificial intelligence. Its central hypothesis argues that a tradition of literary, artistic, and other media forms of cultural production on human-robot relationships particular to Japan is currently being built into emotionally-intelligent companion robots with the ability to understand, record, and elicit emotions in its users, consequently expanding the capacities for humans to create affective bonds with machines and transforming structures of intimacy that sustain traditional social institutions. In its most ambitious claim, EMTECH argues that this cultural tradition has played a primary role in inspiring the recently-emerging mass production of domestic robots with technology that can register and record facial expressions, heart rate, skin conductance, and other signs of affect not consciously recognized by humans, thus generating new kinds of scientific data on human affect that fundamentally challenges previous understandings of emotion. Through the textual analysis of literary work on robot imaginaries and ethnographic fieldwork on human-robot interaction in homes, palliative care centers, and engineering laboratories, EMTECH\u2019s purpose is to collect qualitative data on new technologies of emotion management in order to advance literary and cultural theory\u2019s contributions to the affective sciences, as well as to inform public discussions on issues of data collection, privacy, and other ethical concerns raised by the adoption of emotionally-intelligent robots in the home. Leveraging research in the humanities to critique emotional models employed by robotics engineers and designers, and implementing novel research methods such as the use of robots in both literary critique and ethnographic fieldwork, EMTECH promises to yield groundbreaking data of both theoretical and methodological application across the human sciences.", "To": ["2022-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["714666"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["TECHNISCHE UNIVERSITEIT EINDHOVEN", "CHALMERS TEKNISKA HOEGSKOLA AB", "KATHOLIEKE UNIVERSITEIT LEUVEN", "NXP SEMICONDUCTORS NETHERLANDS BV", "ERICSSON AB", "ORBAN MICROWAVE PRODUCTS NV"], "EU_Contribution": ["EUR 3 078 374,40"], "Project_Title": ["Silicon-based Ka-band massive MIMO antenna systems for new telecommunication services"], "Total_Cost": ["EUR 3 078 374,40"], "Country": ["Netherlands", "Sweden", "Belgium", "Netherlands", "Sweden", "Belgium"], "Project_ACR": ["SILIKA"], "Technology_Description": "The continuously growing need for higher data-rates and, therefore, more signal bandwidth in wireless communications, requires the use of multi-antenna base stations employing the recently introduced massive Multiple-Input-Multiple-Output (MIMO) concept and operating at millimeter-wave frequencies, e.g. 30 GHz. However, the implementation of such complex antenna systems into highly-integrated, energy- and cost-effective solutions is very challenging. Therefore, we propose an innovative antenna system concept utilizing silicon semiconductor electronics that can generate or receive at millimeter-wave frequencies in order to truly expand wireless communications into the outer limits of radio technology. SILIKA establishes a training network with leading R&D labs from European industries, universities and technology institutes in the domain of wireless infrastructure. This will be achieved by a multi-disciplinary approach combining expertise in all required areas to create a breakthrough towards millimeter-wave multi-antenna systems for energy-efficient and low-cost base stations for 5G wireless infrastructure. In the SILIKA Graduate School we will train 12 ESRs with post-master level technical courses and industrial workshops which are complemented by several professional-skill training modules relevant for working in multi-disciplinary project teams. All ESRs will perform secondments in an industrial setting. The SILIKA consortium consists of key European players in the field of wireless infrastructure with a complementary field of expertise and with a proven track-record in joint collaborations. As a consequence, SILIKA will provide the ESRs with a comprehensive set of transferable skills relevant for innovation and long-term employability. The high level of participation of leading industries will ensure that the scientific results of SILIKA will be transferred to future products in the area of wireless infrastructure which will benefit the European economy.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-09-01"], "Project_ID": ["721732"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "BOARD OF GOVERNORS OF THE COLORADO STATE UNIVERSITY SYSTEM", "TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK"], "EU_Contribution": ["EUR 251 857,80"], "Project_Title": ["To develop a novel class of metalloenzymes for application in novel asymmetric C-H activation chemistry."], "Total_Cost": ["EUR 251 857,80"], "Country": ["United Kingdom", "United States", "United States"], "Project_ACR": ["METENZ"], "Technology_Description": "Chemical synthesis through the activation of inert C-H bonds allows scientist to efficiently assemble complex organic molecules which have specific function. We aim to develop a novel class of metalloenzymes, where a transition metal catalyst is embedded into a genetically engineered protein, for rhodium catalysed asymmetric C-H activation reactions. We believe that the approach of incorporating a transition metal into a protein will allow for precise control of the chemical environment around the transition metal, allowing us to control many key outcomes of the chemical reaction such as enantioselectivity, regioselectivity and reaction rates. This technology will allow for the development of C-H activation reactions that have previously been inaccessible to the synthetic chemistry community.", "To": ["2018-03-31, Grant Agreement terminated |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-04-01"], "Project_ID": ["656455"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITEIT ANTWERPEN", "UNIVERSITEIT ANTWERPEN"], "EU_Contribution": ["EUR 1 499 250"], "Project_Title": ["What makes leaves fall in autumn? A new process description for the timing of leaf senescence in temperate and boreal trees"], "Total_Cost": ["EUR 1 499 250"], "Country": ["Belgium", "Belgium"], "Project_ACR": ["LEAF-FALL"], "Technology_Description": "Leaf phenology is a key component in the functioning of temperate and boreal deciduous forests. The environmental cues for bud-burst in spring are well known, but little is known about the cues controlling the timing of leaf fall in autumn. Leaf fall is the last stage of leaf senescence, a process which allows trees to recover leaf nutrients. We urgently need to understand the controls timing leaf senescence to improve our projections of forest growth and climate change. I propose a new general paradigm of the onset of leaf senescence, hypothesizing that leaf senescence is triggered by the cessation of tree growth in autumn. I expect that: (i) in the absence of growth-limiting environmental conditions, tree growth cessation directly controls leaf-senescence onset; and (ii) in the presence of growth-limiting conditions, photoperiod controls leaf-senescence onset \u2013 this prevents trees from starting to senesce too early. I will test these hypotheses with a combination of: (i) manipulative experiments on young trees - these will disentangle the impact of photoperiod from that of other factors affecting tree growth cessation, namely: temperature, drought and soil nutrient availability; (ii) monitoring leaf senescence and growth in mature forest stands; (iii) comparing the leaf senescence dynamics of four major tree species (Fagus sylvatica, Quercus robur, Betula pendula and Populus tremula) in four European locations spanning from 40\u00ba to 70\u00ba N; and (iv) integrating the new paradigm into a model of forest ecosystem dynamics and testing it for the major forested areas of Europe. The aim is to solve the conundrum of the timing of leaf senescence in temperate and boreal deciduous trees, provide a new interpretation of the relationship between leaf senescence, tree growth and environment, and deliver a modelling tool able to predict leaf senescence and tree growth, for projections of forest biomass production and climate change.", "To": ["2022-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-02-01"], "Project_ID": ["714916"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["UNIVERSITY OF YORK"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Semi-Parametric Econometric Models: Health, Obesity and Patient Expenditures"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SPEM"], "Technology_Description": "Econometric modelling of healthcare costs serves many purposes: to obtain key parameters in cost-effectiveness analyses; to implement risk adjustment in insurance systems; and to examine the impact of risk factors such as smoking and obesity. Modelling healthcare costs is challenging because the cost data are typically non-negative, heavy tailed and highly skewed. ", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["740654"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["WEIZMANN INSTITUTE OF SCIENCE", "WEIZMANN INSTITUTE OF SCIENCE"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Elimination of Senescent Cells Approach for treatment of COPD"], "Total_Cost": ["EUR 150 000"], "Country": ["Israel", "Israel"], "Project_ACR": ["ESCAPE_COPD"], "Technology_Description": "Chronic Obstructive Pulmonary Disease (COPD) is estimated to affect up to 600 million people worldwide and by 2020 it will become the third most frequent cause of death. In Europe alone, COPD affects up to 10% of people (i.e. more people than breast cancer and diabetes) and it takes the life of around 300,000 Europeans each year. Current therapies are associated with a variety of side effects some of which can be acute and even life threatening. Moreover, none of the existing medications for COPD has been shown conclusively to modify the long-term decline in lung function thus, COPD remains a disease with a significant unmet medical need.", "To": ["2018-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["727218"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["PLANAFFHO - PLANning for AFFordable HOusing"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["PLANAFFHO"], "Technology_Description": "PLANAFFHO - PLANning for AFFordable HOusing, aims to examine how land-use planning has contributed to the provision of affordable housing for low-income people and has promoted a mix of housing tenures within new developments in three capital cities - Copenhagen, Lisbon, and London, over the last ten years. The first aim and principal focus of the research is therefore investigating planning and housing activities in three cities (Copenhagen, Lisbon and London) that seek to address problems of housing shortage, affordability, and segregation of housing tenures. The research aims to provide practical knowledge and innovative advice to decision-makers on what can be done regarding these huge societal challenges. The second aim of the research, underpinning and informing the former, is to make a contribution to the theoretical and methodological advancement of international comparative research on housing and land-use planning. In order to meet these aims, the theoretical and methodological skills of the candidate will be strengthened at the Cambridge Centre for Housing and Planning Research, located within the Department of Land Economy, University of Cambridge, and led by Professor Michael Oxley. With over 25 years of experience and a proven track record of providing evidence and analysis to influence and support better policy and practice in several areas, the Centre is well-placed to broaden her practical experience of housing and planning matters, from both an interdisciplinary and a comparative perspective. The research will involve short-term visits to planning departments and non-profit housing associations in Copenhagen, Lisbon, and London, aiming to contribute to a mutual exchange of knowledge. During the visits, the candidate will collect data and conduct fieldwork. The data will be analysed though the lens of spatial and social scrutiny, an optic with which an ER with a background in geography, spatial planning, and sociology is already familiar.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["747257"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["WEIZMANN INSTITUTE OF SCIENCE", "WEIZMANN INSTITUTE OF SCIENCE"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Single cell genomic analysis and perturbations of hematopoietic progenitors: Towards a refined model of hematopoiesis"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Israel", "Israel"], "Project_ACR": ["HemTree2.0"], "Technology_Description": "Hematopoiesis is an important model for stem cell differentiation with great medical significance.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["724471"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET", "KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 1 987 811"], "Project_Title": ["Reprogramming of small RNA function in plant-pathogen interactions"], "Total_Cost": ["EUR 1 987 811"], "Country": ["Denmark", "Denmark"], "Project_ACR": ["PATHORISC"], "Technology_Description": "RNA silencing relies on small RNAs that act in RNA induced silencing complexes (RISCs). RISCs use base pairing to select mRNAs or invading nucleic acids such as viruses for repression. RNA silencing may facilitate gene expression changes, for example in host-pathogen interactions. Such changes require reprogramming of RISC, since a different set of RNAs must be rapidly repressed upon pathogen perception. RISC reprogramming is non-trivial: new small RNAs must be produced and be rapidly incorporated into RISC, while unwanted repression by pre-existing RISCs must be eliminated. This project focuses on understanding three central aspects of RISC reprogramming in plant-pathogen interactions. First, we will define mechanisms that allow invading RNA, but not self-RNA, to engage in positive feedback loops for small RNA synthesis, and we will investigate the specific importance of these positive feedback loops in antiviral defense. Second, we will explore how rapid proteolysis of the central RISC component ARGONAUTE1 (AGO1) governs rapid incorporation of newly synthesized small RNA. We will also explore the hypothesis that non-RNA bound AGO1 is degraded to minimize vulnerability to pathogens that use small RNAs as virulence factors to repress host immune signaling. The relevance of these mechanisms of AGO1 proteolysis in plant immunity will be investigated. These studies take advantage of our recent discovery of proteins required specifically for turnover of AGO1. Finally, we explore the hypothesis that rapid chemical modification of mRNA by N6-adenosine methylation (m6A) may bring mRNAs with poor small RNA binding sites under RISC repression. This scenario is supported by interactions between m6A reader proteins and AGO1 discovered in current work in the group. This mechanism may enable reprogramming of RISC specificity rather than composition upon pathogen perception. Our project will fill gaps in knowledge on RNA silencing and elucidate their importance in plant immunity.", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["726417"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 200 194,80"], "Project_Title": ["Mechanistic and therapeutic implications of microRNA deregulation for drug resistance in bile duct cancer"], "Total_Cost": ["EUR 200 194,80"], "Country": ["Denmark"], "Project_ACR": ["MiRCHOL"], "Technology_Description": "Cholangiocarcinoma (CCA) is a dismal type of liver cancer which incidence has more than doubled the last 20 years and mortality rate in Europe alone increased 37%, reflecting the limited treatment options. In >70% of patients CCA is unresectable due to advanced stage of disease at diagnosis, resulting in a 5% 5-year survival rate. CCA is characterized by molecular and clinical heterogeneity, complicating therapy and assessment of drug efficacy. Tumor heterogeneity is emphasized in limited response of therapy (drug resistance) and besides genomic instability a likely consequence of deregulated pathways under control of microRNAs (miRs). Each miR can regulate multiple genes/pathways, directly linking them to tumor heterogeneity. Deregulation of miRs can cause/control chemoresistance in other cancers, but in CCA their role is yet unclear. Thus, detailed characterization of miRs in CCA, focusing on their impact in drug resistance is urgently needed. Hence, I have 3 specific aims of this proposal: to 1) characterize the deregulated expression pattern of miRs involved in CCA pathogenesis and integrate this data with transcriptomes obtained from matched patients; 2) determine the role of deregulated miRs in control of chemoresistance, and 3) modulate by genome-editing key deregulated miR(s) targeting chemoresistant genes using the novel `CRISPR-Mir\u2019 method. Achievement of these aims will yield key new insights into the role of miRs in orchestrating CCA progression and metastasis, as well as their involvement in drug resistance. My findings will have an impact on the society and in particular in patient outcome. Dr. Andersen, a world-wide expert in the molecular pathogenesis of CCA with a vast experience in genome medicine, will supervise the project. Successful completion of this proposal will enable me to expand my scientific expertise (plus technical and transferable skills) and to establish myself as an independent researcher in hepatobiliary and translational research.", "To": ["2019-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["746068"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 200 194,80"], "Project_Title": ["Development of tools to increase product yields in cyanobacteria using a synthetic biology approach"], "Total_Cost": ["EUR 200 194,80"], "Country": ["Denmark"], "Project_ACR": ["Cynthetica"], "Technology_Description": "Cyanobacteria are versatile photosynthetic organisms that have attracted interest as a sustainable biotechnological host chassis. The toolkit for these organisms is growing fast, however, limitations such as low productivities are still a major drawback for this emerging technology. Cynthetica will address the issue of recombinant product yields and develop two separate tools that can be universally applied for product synthesis in cyanobacteria. ", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["745959"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["A Markedness Account of Romance Clitic Systems"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["MARCS"], "Technology_Description": "This project deals with Romance clitic pronouns, i.e. pronominal elements that i) cannot bear primary stress and ii) may have a strong counterpart occurring in a different syntactic position.", "To": ["2017-12-31, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["658784"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Impacts of Diseases on Wild Bird Populations"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["DisWildPop"], "Technology_Description": "Understanding what makes organisms ill, and the implications of diseases for dynamics and persistence of wild populations are receiving increased attention from epidemiologists, animal and public health scientists and evolutionary biologists since diseases have major impacts on human and non-human populations. Here I propose a research that capitalizes from recent advances in disease identification, demographic modelling and advanced phylogenetic comparative analyses to investigate the links between pathogen prevalence and life histories, demography and social behaviour of hosts. Using birds as model organisms, first I propose to investigate how prevalence of major causative agents of disease vary across taxa with variable patterns of life history, ecology and social behaviour. Second, I aim to investigate whether prevalence of a wide range of pathogens differ between males and females, and whether these differences result from the distinct roles they play in reproduction. Finally, I will examine whether sex differences in pathogen prevalence predict sex-specific mortality and biased sex ratios. To achieve these Objectives, I will integrate data and methodology from wildlife disease biology, behavioural ecology and population demography. The Fellowship will enhance my analytic skills and provide training in three major fields: disease biology, comparative phylogenetic analyses and population demography. The Do\u00f1ana Biological Station (Spain) will provide a unique opportunity to acquire these skills en route to address the project Objectives, and excellent prospects for career development and interdisciplinary collaborations. In addition, the proposed project will have knock-on benefits for biodiversity conservation by providing key knowledge on the capacities of wild birds to respond to disease threats across diverse ecosystems.", "To": ["2019-02-28, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-03-01"], "Project_ID": ["705334"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["MUSEUM NATIONAL D'HISTOIRE NATURELLE"], "EU_Contribution": ["EUR 256 410"], "Project_Title": ["Eavesdropping on the tropics: assessment of climate change impacts on amphibians through passive acoustic monitoring"], "Total_Cost": ["EUR 256 410"], "Country": ["France"], "Project_ACR": ["EAVESTROP"], "Technology_Description": "Recent climate change is a major threat for conservation of amphibian diversity, the most endangered group of vertebrates. Species distribution models derived from functional traits have been proposed to provide more robust predictions of future climate-induced shifts in environmental suitability than commonly used correlative models. The proposed project aims, for the first time, to examine species vulnerability to climate change through a novel integration of two scientific disciplines, bioacoustics and biogeography, thanks to the use of new tools in acoustic monitoring, signal processing and species distribution modelling. We will first explore how a key and environment-dependent behavioural trait in amphibian anurans (i.e., reproductive calling behaviour) responds across climatic gradients and subsequently expand these findings into larger temporal and spatial scales through mechanistic approach at two levels of organisation, species and community. The MSCA is proposed as a 3-year GF. One of the most cited research groups in ecology (UFG) will host the fellow during the outgoing phase in Brazil, where data collection, first analyses, and training in biogeography will be conducted. The third year of return to the host organisation in France, with a leading group in bioacoustics and signal processing (MNHN), will be devoted to training in acoustic diversity indices, software development, and most transfer and dissemination activities. The MSCA will enable the fellow to be one of the first researchers with expertise in both bioacoustics and biogeography and hence will open up the best career possibilities for him and new collaboration opportunities for the host organisations. As the first using this novel approach, the MSCA is expected to provide advances in these two disciplines as well as to promote new scientific pathways. A series of outreach activities will also contribute to public education and awareness of amphibian decline and climate change threats.", "To": ["2018-12-31, Grant Agreement terminated |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["661408"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["COLLEGE DE FRANCE"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Quantum simulation of transport properties in arbitrary shaped potential landscapes with ultracold bosonic atoms"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["BosQuanTran"], "Technology_Description": "In solid state systems transport experiments are among the most important probes to investigate the properties of different phases of matter. A number of intriguing observations have been reported where the interaction between the charge carriers plays a significant role. One of the most prominent examples currently explored in the laboratories are high-Tc superconductors and fractional-quantum-Hall insulators. Quantum-mechanical systems whose properties are governed by the interaction between its constituents are computationally difficult to handle. In most cases numerical results can only be obtained for small systems or in reduced dimensions. One possibility to overcome these limitations is to perform analog quantum simulations with ultracold atoms. The basic idea behind these experiments is to built artificial model systems using the bottom-up approach: Bosonic and fermionic atoms are cooled to ultra-low temperatures to reach quantum degeneracy. Subsequently the atoms are confined in engineered magnetic and optical potentials realizing closed quantum systems that are, to a good approximation, decoupled from their environment. This approach has the advantage that the system parameters such as interactions, dimensionality, geometry or the amount of disorder can be controlled externally and even varied dynamically. The rapid progress in this research area makes them promising candidates to provide stimulating input on current condensed matter problems. It initiated a whole new field known as atomtronics, which aims at designing electronic-like circuits with potentially interesting applications. Recently developed techniques allow for an engineering of tailored trapping geometries and high-resolution imaging, which provides new insight in the study of quantum transport. In combination with the recent success in realizing artificial magnetic fields, these techniques open the door to future studies of topological transport phenomena.", "To": ["2018-02-28, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["703926"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSIDAD REY JUAN CARLOS"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Linking plant functional diversity to ecosystem multifunctionality in arid systems worldwilde"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["DRYFUN"], "Technology_Description": "The relationship between plant functional diversity and ecosystem functioning has been hotly debated, and previous research has shown direct feedbacks effects of functional community structure on ecosystem processes. However, previous studies have not considered indirect effects via changes in biotic interactions, and this is an emerging and crucial challenge for community and ecosystem ecologists. The DRYFUN project aims to assess the ultimate effects of biotic interactions on ecosystem processes of global drylands, by coupling a multi-trait approach with an observational database from 236 sites distributed among all continents except Antarctica. Its main objectives are to: (i) test the importance of abiotic and biotic processes for community structure in global drylands, (ii) assess the importance of within- and between-species trait variability for functional diversity, (iii) assess both the direct and indirect impact of dryland functional diversity on ecosystem multifunctionality (i.e., the provision of several ecosystem processes simultaneously; multifunctionality hereafter) at multiple spatial scales and (iv) explore the importance of taxonomic, functional and phylogenetic diversities on multifunctionality. The DRYFUN project is a unique opportunity to test the universal impact of functional diversity on dryland ecosystem functioning, and to provide data for establishing relevant management and restoration strategies for drylands.", "To": ["2017-09-30, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["656035"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Secure information processing in quantum networks"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["seQureNet"], "Technology_Description": "The promise of future quantum computers to substantially speed up computations has been advertised widely since the early days of the field. But there is a novel and fundamental aspect of devices based on quantum-mechanical principles that has just started to be explored: Quantum computers can preserve the privacy of computations. This aspect is a distinct new advantage of quantum computers over their classical counterparts. An entire class of unprecedented computations becomes feasible, in which the user data and the whole computation remain perfectly private \u2013 a feature impossible to achieve with classical computers. The main focus of this project is to exploit this feature and to implement secure photonic quantum information processing in distributed quantum networks. These networks consist of clients and small-scale quantum computers connected by communication channels. Photons are chosen as they are the ideal carriers for sending information over long distances. The clients can securely delegate computations to the quantum computers, such that neither the data nor the computation is revealed to the computers or any potential eavesdropper. The project will, first, elucidate how quantum resources boost the security of classical computations; second, demonstrate secure quantum computations over long distances and study their verification; and third, examine practical security aspects of implementations. The research will leverage the experimental state-of-the-art by adapting new photonic quantum technologies such as integrated photon sources and waveguide quantum circuits. Moreover, highly-efficient superconducting detectors will be applied to achieve excellent quantum control of the photons. This research is highly innovative and will be pivotal in the researcher\u2019s career development and for becoming an independent research group leader, as it enables acquiring both key scientific knowledge and developing complementary skills.", "To": ["2017-04-14, Grant Agreement terminated |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-04-15"], "Project_ID": ["658073"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITE DE PICARDIE JULES VERNE", "THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN", "LIMITED LIABILITY COMPANY RESEARCH AND PRODUCTION ENTERPRISE I.F. LAB", "UNIVERSIDAD DE CHILE", "Instituto Nacional de Higiene, Epidemiolog\u00eda y Microbiolog\u00eda"], "EU_Contribution": ["EUR 864 000"], "Project_Title": ["Microelements in Life Expectancy and Aging"], "Total_Cost": ["EUR 864 000"], "Country": ["France", "United Kingdom", "Ukraine", "Chile", "Cuba"], "Project_ACR": ["MILEAGE"], "Technology_Description": "Increased longevity with a high quality of life is desirable not only for personal life-satisfaction but also for reducing healthcare costs and for increasing the socioeconomic contributions of individuals in countries with ageing population demographics. Lifelong lifestyle has an important impact on health status in older age and adequate nutrition plays a key role in maintaining cellular functions within normal limits. Microelements such as zinc (Zn) and copper (Cu) are essential for life and are involved in the normal functioning of thousands of proteins. The dysregulation of these metals leads to perturbed homeostasis, disease and diminished quality of life. In this study, the molecular mechanisms by which ageing affects Zn and Cu absorption and excretion will be determined, and the consequent impact on metal flux and transport kinetics will be expressed by mathematical modelling. The project output will include a predictive model for the impact of ageing on Zn and Cu homeostasis, informing intervention with dietary advice or supplementation to improve longevity. The consortium combines intersectoral and interdisciplinary expertise from 3 EU and 2 partner countries with established links and clear potential for knowledge exchange and transfer of skills. The consortium objectives are:", "To": ["2021-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2017-05-01"], "Project_ID": ["734931"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN", "THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN"], "EU_Contribution": ["EUR 1 860 008,75"], "Project_Title": ["SHARECITY: Assessing the practice and sustainability potential of city-based food sharing economies"], "Total_Cost": ["EUR 1 860 008,75"], "Country": ["Ireland", "Ireland"], "Project_ACR": ["SHARECITY"], "Technology_Description": "With planetary urbanization fast approaching there is growing clarity regarding the unsustainability of cities, not least with respect to food consumption. Sharing, including food sharing, is increasingly being identified as one transformative mechanism for sustainable cities: reducing consumption; conserving resources, preventing waste and providing new forms of socio-economic relations. However, such claims currently rest on thin conceptual and empirical foundations. SHARECITY will identify and examine diverse practices of city-based food sharing economies, first determining their form, function and governance and then identifying their impact and potential to reorient eating practices. The research has four objectives: to advance theoretical understanding of contemporary food sharing economies in cities; to generate a significant body of comparative and novel international empirical knowledge about food sharing economies and their governance within global cities; to design and test an assessment framework for establishing the impact of city-based food sharing economies on societal relations, economic vitality and the environment; and to develop and implement a novel variant of backcasting to explore how food sharing economies within cities might evolve in the future. Providing conceptual insights that bridge sharing, social practice and urban transitions theories, SHARECITY will generate a typology of food sharing economies; a database of food sharing activities in 100 global cities; in-depth food sharing profiles of 7 cities from the contrasting contexts of USA, Brazil and Germany, Greece, Portugal, Ireland and Australia; a sustainability impact toolkit to enable examination of city-based food sharing initiatives; and scenarios for future food sharing in cities. Conducting such frontier science SHARECITY will open new research horizons to substantively improve understanding of how, why and to what end people share food within cities in the 21st Century.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["646883"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["SOFTWARE IMPROVEMENT GROUP B.V", "SINGULARLOGIC ANONYMI ETAIREIA PLIROFORIAKON SYSTIMATON KAI EFARMOGON PLIROFORIKIS", "ATHENS UNIVERSITY OF ECONOMICS AND BUSINESS - RESEARCH CENTER", "UNIVERSIDAD REY JUAN CARLOS", "BITERGIUM SLL", "TECHNISCHE UNIVERSITEIT DELFT"], "EU_Contribution": ["EUR 2 236 902,48"], "Project_Title": ["Software ENgineering in Enterprise Cloud Applications systems"], "Total_Cost": ["EUR 2 236 902,48"], "Country": ["Netherlands", "Greece", "Greece", "Spain", "Spain", "Netherlands"], "Project_ACR": ["SENECA"], "Technology_Description": "The growth of cloud computing is phenomenal, with vendors experiencing yearly growth over 90%. This reflects the rate at which organizations and individuals are leaving the comfort of tried and tested solutions to move into promising but uncharted territory.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-EID - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-EID)"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["Netherlands"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2015-01-01"], "Project_ID": ["642954"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN"], "EU_Contribution": ["EUR 159 900"], "Project_Title": ["Re(search)"], "Total_Cost": ["EUR 159 900"], "Country": ["Ireland"], "Project_ACR": ["reSEARCH"], "Technology_Description": "Re(search) will connect the citizens of Dublin with research through two fringe-festival events held in 2016 and in 2017. For each event, Dubliners will be invited to the iconic Front Square of Trinity College Dublin where they will explore how research is addressing societal challenges (the same societal challenges laid out in H2020). The societal challenges will be explored using a range of formats including comedy, drama, dining, story-telling, and citizen-science. These have been chosen to spark conversations between researchers and citizens on issues that matter to people\u2019s lives. Conversations will allow citizens to construct their own views on research topics and the role of research in our society (and as a career). Constructivist approaches to learning are known to lead to enhanced learning outcomes in formal learning settings. This proposal is based on the idea that a constructivist approach to learning can also be applied to informal learning environments, such as Re(search) Night.", "To": ["2017-11-30, closed project |"], "Meta": [""], "Topic_s": ["MSCA-NIGHT-2016 - European Researchers' Night"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["722628"], "Call_for_Proposal": ["H2020-MSCA-NIGHT-2016"]}, -{"Partners": ["UNIVERSITY OF NORTHUMBRIA AT NEWCASTLE", "UNIVERZA V LJUBLJANI", "INSTITIUID TEICNEOLAIOCHTA BHAILE ATHA CLIATH", "DUBLIN CITY UNIVERSITY", "UNIWERSYTET WARSZAWSKI", "POLITECHNIKA WARSZAWSKA", "ELIESHA TRAINING LIMITED", "FUNDACJA KREATYWNE MAZOWSZE", "ISME LIMITED", "Kolektor Group d.o.o., vodenje in upravljanje dru\u017eb", "MEDEX ZIVILSKA INDUSTRIJA DOO", "KYUNGPOOK NATIONAL UNIVERSITY", "CHONNAM NATIONAL UNIVERSITY"], "EU_Contribution": ["EUR 954 000"], "Project_Title": ["Global Entrepreneurial Talent Management 3"], "Total_Cost": ["EUR 1 224 000"], "Country": ["United Kingdom", "Slovenia", "Ireland", "Ireland", "Poland", "Poland", "United Kingdom", "Poland", "Ireland", "Slovenia", "Slovenia", "South Korea", "South Korea"], "Project_ACR": ["GETM3"], "Technology_Description": "GETM3 \u2013 Global Entrepreneurial Talent Management 3 - focuses on young talent as a key driver of future development, developed through co-operation of 3 stakeholders: employers (inc MNC & SME\u2019s), universities and students/graduates. Despite a widely recognized importance of young talent (e.g. Europe 2020), its potential remains largely untapped. They are educated and entrepreneurial and yet experience instability in employment. At the same time, employers report skills mismatch and difficulties with attracting, managing and retaining young talent. To tackle this paradoxical situation, an innovative, multi-perspective approach is needed, reinforced by our 15 partner consortium; comprising of a transnational, inter-disciplinary, inter-generational, gender balanced and inter-sectorial research team. ", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["734824"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "INSTITUT ZA FIZIKU", "TECHNISCHE UNIVERSITEIT DELFT", "SENZOR INFIZ DOO", "FUNDACIO INSTITUT CATALA DE NANOCIENCIA I NANOTECNOLOGIA", "KATHOLIEKE UNIVERSITEIT LEUVEN"], "EU_Contribution": ["EUR 769 500"], "Project_Title": ["Designing Advanced Functionalities through controlled NanoElement integration in OXide thin films"], "Total_Cost": ["EUR 769 500"], "Country": ["Spain", "Serbia", "Netherlands", "Serbia", "Spain", "Belgium"], "Project_ACR": ["DAFNEOX"], "Technology_Description": "The aim of this project is to develop new inexpensive, scalable and efficient bottom \u2013up approach for positioning nanoobjects in regular patterns and to implement them in optoelectronic technology, which is the major challenge in nanotechnology today. The synergy between the quasi zero-dimensional elements and functional oxides with an exceptional range of properties (ferromagnetism, ferroelectricity, \u2026) opens a completely new concept to nanoelectronics. Devices based on these materials would offer functionality beyond the achievable limits, with wide range of applications from spintronics and catalytics to optoelectronics.", "To": ["2018-06-30, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2015-07-01"], "Project_ID": ["645658"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["GOETEBORGS UNIVERSITET"], "EU_Contribution": ["EUR 173 857,20"], "Project_Title": ["Bio-physical processes around marine snow aggregates"], "Total_Cost": ["EUR 173 857,20"], "Country": ["Sweden"], "Project_ACR": ["BIPHA"], "Technology_Description": "Advancing our understanding of biologically driven sequestration of carbon is crucial given the rapidly increasing atmospheric CO2 concentrations. Diatoms are the most common type of phytoplankton and, as the ocean\u2019s biological carbon pump, a key component in this process. Diatom aggregates, in particular, comprise a significant fraction of sinking particulate matter drawing down atmospheric carbon to the depths of the ocean. Diatoms produce transparent exopolymeric particles (TEP), a gel-like sticky sugary substance, which plays a significant role in the subsequent coagulation of diatoms into aggregates as their blooms terminate. These sinking aggregates are composed of diatoms, detritus and faecal pellets and are so-called marine snow aggregates. ", "To": ["2017-10-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-11-01"], "Project_ID": ["660481"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN"], "EU_Contribution": ["EUR 187 866"], "Project_Title": ["Quantum Entanglement And Holography"], "Total_Cost": ["EUR 187 866"], "Country": ["Ireland"], "Project_ACR": ["QEAH"], "Technology_Description": "Entanglement Entropy and other measures of quantum entanglement have recently given great insights into the physics of both quantum field theories and gravity. ", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["659151"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["STICHTING NIOZ, KONINKLIJK NEDERLANDS INSTITUUT VOOR ONDERZOEK DER ZEE"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["Electrogenic NItrate Reduction In marine Sediments"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["ENIRIS"], "Technology_Description": "Recently, a novel type of long, filamentous bacteria has been discovered, which are capable of guiding electrical currents over centimeter distances. These so-called \u201ccable bacteria\u201d were first isolated from marine sediments, and laboratory experiments demonstrate that electrons are passed on from cell to cell along the longitudinal axis of the filaments. This long-distance electron transport radically extends the physiological capacities of prokaryotes, and profoundly changes our understanding of biogeochemical transformations in marine sediments. ", "To": ["2018-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Research Organisations"], "From": ["2016-04-01"], "Project_ID": ["656385"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN"], "EU_Contribution": ["EUR 187 866"], "Project_Title": ["Geography of Demography: modelling plant population responses to global habitat patterns"], "Total_Cost": ["EUR 187 866"], "Country": ["Ireland"], "Project_ACR": ["GEODEM"], "Technology_Description": "Mankind is profoundly altering the environments in which plant and animal populations live. An era of such massive habitat rearrangements requires ecologists to take new approaches to increase our understanding of species distribution and likelihood of persistence worldwide. Improved ecological models of range-wide persistence and response to the simultaneous threats of climate change, habitat destruction and landscape reconfiguration are required to inform management of biodiversity at large scales. GEODEM brings together global datasets of plant distribution and demography to gain insight into how the geographic configuration of habitats affects growth, survival and reproduction of more than 500 plant species worldwide. The project has two main objectives: 1. Geographic Range Pattern Analysis: Using species distribution models and global spatial statistics tools to quantify and compare spatial patterns of suitable environmental conditions across species\u2019 biogeographic ranges. 2. Landscape Demography: Testing how the spatial arrangement of suitable habitat within the geographic space can inform population responses to environmental gradients. The fellow will be supervised by and collaborate with world leaders in spatial ecology in Ireland and other European countries to accomplish her goals. The prestigious Marie Sk\u0142odowska-Curie fellowship will enable her to develop expertise in currently disparate areas of species distribution modelling and demography and place her in a unique position to make significant contributions to the urgent problem of population persistence at large scales during this era of global change. It will enable the fellow to build an independent research program in Europe after gaining research experience in top universities in Canada and Australia.", "To": ["2017-05-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-06-01"], "Project_ID": ["658651"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSIDAD DE BURGOS"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Novel Nanoporous PZT Materials for Efficient Utrasonic Biomedical Sensors"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["Nano-PieZoelecTrics"], "Technology_Description": "Piezoelectric materials have become a key technology for a wide range of industrial and consumer products with a robust global market of U.S. $21 billion in the last 2013. Current technology includes applications on actuators, ultrasonic motors, sensor arrays for structural health monitoring, transformers, micro-energy harvesting devices, hydrophones, high resolution ultrasonic medical imaging, computer disk drives, and accelerometers in mobile phones and notebooks. Currently the most important piezoelectric ceramic materials are based on mixed oxide crystal system consisting of lead, zirconium and titanium, well known as lead zirconate titanate (PZT). Cost-effective and efficient synthetic strategies, structural modifications and doping by foreign ions represent the key steps to significantly improve the performance of PZT materials, such as piezoelectric, dielectric and mechanical stability properties. In this frame, we purpose a new research methodology based on the preparation, characterization and testing of hierarchical porous PZT-doped using alternative synthetic approaches (EISA method) and new doping materials (porous Mg-Niobate, Graphene/Molybdenite and Nanocellulose) to achieve important innovations and overcome the current state of art on the field of hydrophones and high resolution ultrasonic medical applications. Innovations are represented by the preparation of highly-efficient porous PZT matrices, not yet reported in the literature, with very-high surface area whit the idea to enhance the contact between PZT-matrix and media (water, medical gels, etc) and then increasing the sensibility and piezoelectric response of the device. Regarding new doping approaches, Nb-source will be nano-confined into the PZT matrices using the pores as hosting elements with the advantage of constraining dopants in nanoscale. Graphene/Molybdenit nanocomposite and Nanocellulose will be also used to replace critical Nb as also recently recommend by the European guidelines.", "To": ["2018-11-01, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-11-02"], "Project_ID": ["707954"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON", "UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Insect social parasites: behavioural genomics models for understanding the basis of phenotypic evolution"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["SocParPhenoEvol"], "Technology_Description": "Understanding how diversity of life arises at the level of the genes is one of the biggest challenges in modern biology. Genomic methodologies now allow us to dissect the molecular basis of this phenotypic diversity and plasticity. However, we lack an integrated study of key phenotypic traits and their dynamic changes in an ecologically relevant setting, with the associated dynamic nature of the underpinning genes. I propose to use an inter-disciplinary approach, by uniting classical ethology with new molecular tools of genomics, to understand how genes give rise to phenotypic traits and their dynamic plasticity using an insect social parasite system as model. Insect social parasites show striking phenotypic diversity compared to their hosts and have been identified as unique models for understanding the molecular basis of phenotypic diversity and plasticity. Yet, they have remained largely unexploited so far, due to the difficulty of conducting genomic studies on non-model organisms. This project will combine for the first time the transcriptomic (i.e. multiple species comparisons of brain genome-wide RNA-seq analyses followed by candidate gene approach RT-PCR) and behavioural phenotyping in order to reveal the molecular basis of phenotypic diversity in a Polistes paper wasp social parasite system, which comprises the social parasite, the host and a related non host species. This will be a landmark project in the exploding field of Behavioural Genomics as it will ensure high replication in an ecologically relevant setting in wild populations and it will exploit a deep ethological knowledge of the model system to ensure precise integration of behaviour with new methods for dissecting molecular processes. This project offers a unique opportunity to capitalize on molecular and behavioural expertise of the Supervisor and ER, generating the most comprehensive empirical and theoretical body of work to date, thus placing the ER as a leader in this new and exciting field.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["706208"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN", "THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN"], "EU_Contribution": ["EUR 1 499 865"], "Project_Title": ["Late First-Row Transition Metal-Oxo Complexes for C\u2013H Bond Activation"], "Total_Cost": ["EUR 1 499 865"], "Country": ["Ireland", "Ireland"], "Project_ACR": ["HurdlingOxoWall"], "Technology_Description": "The chemical, pharmaceutical, and materials industries rely heavily upon chemicals from oil and natural gas feed-stocks (saturated hydrocarbons) that require considerable functionalisation prior to use. Catalytic oxidative functionalisation (e.g. CH4 + [O] + cat. \u2192 CH3OH), using first row transition metal catalysts, is potentially a sustainable, cheap, and green route to these high-commodity chemicals. However, catalytic oxidation remains a great modern challenge because such hydrocarbons contain remarkably strong inert C\u2013H bonds that can only be activated with potent catalysts. We will take a Nature-inspired approach to designing and preparing powerful oxidation catalysts: we will interrogate the active oxidant, a metal-oxo (M=O) species, to guide our catalyst design. Specifically, we will prepare unprecedented Late first-row transition Metal-Oxo complexes (LM=O\u2019s, LM = Co, Ni, Cu) that will activate the strongest of C\u2013H bonds (e.g. CH4). ", "To": ["2021-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["678202"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN", "THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN"], "EU_Contribution": ["EUR 1 521 875"], "Project_Title": ["Frontier research in arterial fibre remodelling for vascular disease diagnosis and tissue engineering"], "Total_Cost": ["EUR 1 521 875"], "Country": ["Ireland", "Ireland"], "Project_ACR": ["FibreRemodel"], "Technology_Description": "Each year cardiovascular diseases such as atherosclerosis and aneurysms cause 48% of all deaths in Europe. Arteries may be regarded as fibre-reinforced materials, with the stiffer collagen fibres present in the arterial wall bearing most of the load during pressurisation. Degenerative vascular diseases such as atherosclerosis and aneurysms alter the macroscopic mechanical properties of arterial tissue and therefore change the arterial wall composition and the quality and orientation of the underlying fibrous architecture. Information on the complex fibre architecture of arterial tissues is therefore at the core of understanding the aetiology of vascular diseases. The current proposal aims to use a combination of in vivo Diffusion Tensor Magnetic Resonance Imaging, with parallel in silico modelling, to non-invasively identify differences in the fibre architecture of human carotid arteries which can be directly linked with carotid artery disease and hence used to diagnose vulnerable plaque rupture risk.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["637674"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN", "THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN"], "EU_Contribution": ["EUR 1 806 536"], "Project_Title": ["Western banks in Eastern Europe: New geographies of financialisation"], "Total_Cost": ["EUR 1 806 536"], "Country": ["Ireland", "Ireland"], "Project_ACR": ["GEOFIN"], "Technology_Description": "Financialisation, or the growing power of finance over societies and economies, is increasingly recognised as the key feature of contemporary capitalism. However, significant gaps in our understanding of this process remain. Indeed, despite growing recognition that financialisation is an inherently spatial process, a geographically-informed view of financialisation remains underdeveloped. In addition, and related to this, the extent and the ways in which post-socialist \u2018transition\u2019 societies in East-Central Europe have been financialised remain under-researched and under-theorised. Yet, the examination of former state-socialist societies (built on the very opposite economic logic to that of financialisation) provides an unmatched opportunity to learn about financialisation itself, how it \u2018penetrates\u2019 societies and with what social and spatial implications. East-Central Europe in this sense constitutes a unique terrain for frontier research. GEOFIN will address the above shortcomings by producing empirical and theoretical insights to develop a geographically-informed view of financialisation. The objective is to examine how states, banks and households in post-socialist contexts have been financialised and to consider what implications this has for the societies in question and for Europe as a whole. The project will pilot a novel approach based on the concept of \u2018financial chains\u2019 which are understood both as channels of value transfer and as social relations that shape socio-economic processes and attendant economic geographies. A set of interlocking case studies will be mobilised to reveal the different ways in which banks, states and households across post-socialist East-Central Europe are interconnected by financial chains with each other and with a wider political economy. GEOFIN will fundamentally advance our understanding of new geographies of financialisation, opening up new horizons in studies of finance and its future role in the society.", "To": ["2021-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-12-01"], "Project_ID": ["683197"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN", "THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN"], "EU_Contribution": ["EUR 1 382 642,50"], "Project_Title": ["The Neural Determinants of Perceptual Decision Making in the Human Brain"], "Total_Cost": ["EUR 1 382 642,50"], "Country": ["Ireland", "Ireland"], "Project_ACR": ["Human Decisions"], "Technology_Description": "How do we make reliable decisions given sensory information that is often weak or ambiguous? Current theories center on a brain mechanism whereby sensory evidence is integrated over time into a \u201cdecision variable\u201d which triggers the appropriate action upon reaching a criterion. Neural signals fitting this role have been identified in monkey electrophysiology but efforts to study the neural dynamics underpinning human decision making have been hampered by technical challenges associated with non-invasive recording. This proposal builds on a recent paradigm breakthrough made by the applicant that enables parallel tracking of discrete neural signals that can be unambiguously linked to the three key information processing stages necessary for simple perceptual decisions: sensory encoding, decision formation and motor preparation. Chief among these is a freely-evolving decision variable signal which builds at an evidence-dependent rate up to an action-triggering threshold and precisely determines the timing and accuracy of perceptual reports at the single-trial level. This provides an unprecedented neurophysiological window onto the distinct parameters of the human decision process such that the underlying mechanisms of several major behavioral phenomena can finally be investigated. This proposal seeks to develop a systems-level understanding of perceptual decision making in the human brain by tackling three core questions: 1) what are the neural adaptations that allow us to deal with speed pressure and variations in the reliability of the physically presented evidence? 2) What neural mechanism determines our subjective confidence in a decision? and 3) How does aging impact on the distinct neural components underpinning perceptual decision making? Each of the experiments described in this proposal will definitively test key predictions from prominent theoretical models using a combination of temporally precise neurophysiological measurement and psychophysical modelling.", "To": ["2020-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-05-01"], "Project_ID": ["638289"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["UNIVERZA V LJUBLJANI", "UNIVERZA V LJUBLJANI"], "EU_Contribution": ["EUR 2 041 000"], "Project_Title": ["Open Many-body Non-Equilibrium Systems"], "Total_Cost": ["EUR 2 041 000"], "Country": ["Slovenia", "Slovenia"], "Project_ACR": ["OMNES"], "Technology_Description": "We shall study non-equilibrium many-body quantum systems, considering local interactions in one or two spatial dimensions in situations where the generator of time evolution in the bulk of the system is unitary whereas the incoherent processes are limited to the system's boundaries. We foresee a mathematical theory of dynamical quantum phases of matter with applications in the theory of quantum transport and nanoscale devices that manipulate heat, information, charge or magnetization. ", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Slovenia"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["694544"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN", "THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN"], "EU_Contribution": ["EUR 1 447 410"], "Project_Title": ["Plasmonic Enhancement and Directionality of Emission for Advanced Luminescent Solar Devices"], "Total_Cost": ["EUR 1 447 410"], "Country": ["Ireland", "Ireland"], "Project_ACR": ["PEDAL"], "Technology_Description": "Applying photovoltaic (PV) panels to buildings is an important application for wider PV deployment and to achieving our 20% Renewable Energy EU targets by 2020. PEDAL will develop a disruptive PV technology where record increases in efficiency are achieved and costs dramatically reduced; ", "To": ["2020-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-04-01"], "Project_ID": ["639760"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN", "THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN"], "EU_Contribution": ["EUR 1 428 342,50"], "Project_Title": ["Prisons: the Rule of Law, Accountability and Rights"], "Total_Cost": ["EUR 1 428 342,50"], "Country": ["Ireland", "Ireland"], "Project_ACR": ["PRILA"], "Technology_Description": "PRILA will create the first account of how mechanisms for securing rights, ensuring accountability and achieving adherence to the rule of law are experienced in European prisons. Prisons are places where considerable power differentials exist, and are unique sites for the expression of the values which underpin public and prison law. Systems to ensure that prisoners are treated fairly and that rights are upheld are essential to ensure that imprisonment is conducted in ways that are just and promote good order. These are fundamental principles of the \u2018European\u2019 way in penal policy and penal law. Existing accounts of the deployment of penal power overlook key elements of how accountability, the rule of law, and rights are experienced. PRILA will document how prisoners, prison staff, staff of accountability bodies experience structures for ensuring decisions and actions taken in prison are fair, transparent, consistent, subject to appeal and review, and in compliance with principles of human rights. In doing so, PRILA will transform and extend accounts of legitimacy in prisons, judicial review of administrative action, the pains of imprisonment, and understandings of how penal power is experienced. Drawing on the disciplines of public and prison law, human rights, comparative law, and the sociology of punishment, the project will utilise legal, qualitative and quantitative research methods to create an account of how \u2018accountability work\u2019 is experienced. It will also examine how accountability structures are manifestations of penal ideologies or types of prison regimes. The project will advance current judicial and legal conceptions of accountability, the rule of law, and fairness, by reference to how these concepts are experienced in practice, and examine whether and how they are distinctively \u2018European\u2019. The project will thereby support the creation of better penal policies and practices aimed at the protection of the rule of law and rights in the prison context.", "To": ["2021-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-04-01"], "Project_ID": ["679362"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN", "THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN"], "EU_Contribution": ["EUR 1 954 065,02"], "Project_Title": ["Loop amplitudes in quantum field theory"], "Total_Cost": ["EUR 1 954 065,02"], "Country": ["Ireland", "Ireland"], "Project_ACR": ["CutLoops"], "Technology_Description": "The traditional formulation of relativistic quantum theory is ill-equipped to handle the range of difficult computations needed to describe particle collisions at the Large Hadron Collider (LHC) within a suitable time frame. Yet, recent work shows that probability amplitudes in quantum gauge field theories, such as those describing the Standard Model and its extensions, take surprisingly simple forms. The simplicity indicates deep structure in gauge theory that has already led to dramatic computational improvements, but remains to be fully understood. For precision calculations and investigations of the deep structure of gauge theory, a comprehensive method for computing multi-loop amplitudes systematically and efficiently must be found.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["647356"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN", "THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN"], "EU_Contribution": ["EUR 2 213 316,88"], "Project_Title": ["Tuneable 2D Nanosheet Networks for Printed Electronics"], "Total_Cost": ["EUR 2 213 316,88"], "Country": ["Ireland", "Ireland"], "Project_ACR": ["FUTURE-PRINT"], "Technology_Description": "In the future, even the most mundane objects will contain electronic circuitry allowing them to gather, process, display and transmit information. The resulting vast network, often called the Internet of Things, will revolutionise society. To realise this will require the ability to produce electronic circuitry extremely cheaply, often on unconventional substrates. This will be achieved through printed electronics, by the assembly of devices from solution (i.e. ink) using methods adapted from printing technology. However, while printed electronics has been advancing rapidly, the development of new, nano-materials-based inks is required for this area to meet its true potential.", "To": ["2021-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-11-01"], "Project_ID": ["694101"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["UNIVERSIDAD REY JUAN CARLOS", "UNIVERSIDAD REY JUAN CARLOS"], "EU_Contribution": ["EUR 1 894 450"], "Project_Title": ["Biological feedbacks and ecosystem resilience under global change: a new perspective on dryland desertification"], "Total_Cost": ["EUR 1 894 450"], "Country": ["Spain", "Spain"], "Project_ACR": ["BIODESERT"], "Technology_Description": "Changes in climate and land use (e.g., increased grazing pressure), are two main global change components that also act as major desertification drivers. Understanding how drylands will respond to these drivers is crucial because they occupy 41% of the terrestrial surface and are home to over 38% of the world\u2019s human population. Land degradation already affects ~250 million people in the developing world, which rely upon the provision of many ecosystem processes (multifunctionality). This proposal aims to develop a better understanding of the functioning and resilience of drylands (i.e. their ability to respond to and recover from disturbances) to major desertification drivers. Its objectives are to: 1) test how changes in climate and grazing pressure determine spatiotemporal patterns in multifunctionality in global drylands, 2) assess how biotic attributes (e.g., biodiversity, cover) modulate ecosystem resilience to climate change and grazing pressure at various spatial scales, 3) test and develop early warning indicators of desertification, and 4) forecast the onset of desertification and its ecological consequences under different climate and grazing scenarios. I will use various biotic communities/attributes, ecosystem services and spatial scales (from local to global), and will combine approaches from several disciplines. Such comprehensive and highly integrated research endeavor is novel and constitutes a ground breaking advance over current research efforts on desertification. This project will provide a mechanistic understanding on the processes driving multifunctionality under different global change scenarios, as well as key insights to forecast future scenarios for the provisioning of ecosystem services in drylands, and to test and develop early warning indicators of desertification. This is of major importance to attain global sustainability and key Millennium Development Goals, such as the eradication of poverty.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["647038"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN"], "EU_Contribution": ["EUR 187 866"], "Project_Title": ["Controlled Singlet Oxygen Release Photosensitizers in Photodynamic Therapy"], "Total_Cost": ["EUR 187 866"], "Country": ["Ireland"], "Project_ACR": ["CONSORT"], "Technology_Description": "Photodynamic therapy is a form of phototherapy which uses light-sensitive compounds (photosensitizers) that are exposed selectively to light, whereupon they become toxic to targeted malignant and other diseased cells. The photosensitizer creates a highly reactive singlet oxygen species which rapidly reacts with any nearby biomolecules leading to destructive reactions resulting in cell death through apoptosis or necrosis. However, prolonged exposure of tissue to light irradiation causes photosensitivity in patients\u2019 skin. Side effects may include, pain, burning/stinging sensation, itchiness. This proposal aims to develop a conceptually new approach towards photodynamic therapy through an introduction of new type of photosensitizers and corresponding nanomaterials which are capable to generate singlet oxygen upon irradiation, store it by means of binding to special molecular subunits and slowly release singlet oxygen within tissue on a timescale from several hours to several days after light irradiation treatment. The application of such novel material will allow for increasing therapeutic effect and reduced side-effects with respect to conventional PDT due to shorter light treatment duration. Proof of concept will be attained by demonstration of delayed singlet oxygen formation in cancer cells after the light treatment using in vitro models. The project builds on the strengths of the applicant in organic chemistry, photophysics and material science and combines these with new training in biomedicine and drug development to open a new research direction and to enhance cross-European collaboration.", "To": ["2017-09-14, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-15"], "Project_ID": ["655142"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITA' DEGLI STUDI DI SIENA", "UNIVERSITA' DEGLI STUDI DI SIENA"], "EU_Contribution": ["EUR 2 500 000"], "Project_Title": ["Origins of a new Economic Union (7th to 12th centuries): resources, landscapes and political strategies in a Mediterranean region"], "Total_Cost": ["EUR 2 500 000"], "Country": ["Italy", "Italy"], "Project_ACR": ["nEU-Med"], "Technology_Description": "Medieval archaeology over the past thirty years has challenged the canonic history of the rise of Western Europe. First, the collapse of the Roman world in Italy by the 7th century was more profound than had been previously envisaged by historians, leaving rural society, in particular, maintaining comparatively primitive conditions. Secondly, in complete contrast, north-west Europe by stages between the 7th and 9th centuries developed an integrated economic union. Central to this was agricultural intensification coupled with strategic deployment of a silver currency. Thirdly, between the 9th and 12th centuries certain regions of Italy, drawing simultaneously upon connections to the north as well as the Mediterranean, became the economic and political motor of the new Medieval Europe, paving the way for the Renaissance. ", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["670792"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN", "THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN"], "EU_Contribution": ["EUR 1 498 734"], "Project_Title": ["Engineering a scaffold based therapy for corneal regeneration"], "Total_Cost": ["EUR 1 498 734"], "Country": ["Ireland", "Ireland"], "Project_ACR": ["EyeRegen"], "Technology_Description": "Corneal blindness resulting from disease, physical injury or chemical burns affects millions worldwide and has a considerable economic and social impact on the lives of people across Europe. In many cases corneal transplants can restore vision however the shortage of donor corneas suitable for transplantation has necessitated the development of alternative treatments. The aim of this project is to develop a new approach to corneal tissue regeneration. Previous approaches at engineering corneal tissue have required access to donor cells and lengthy culture periods in an attempt to grow tissue in vitro prior to implantation with only limited success and at great expense. Our approach will differ fundamentally from these in that we will design artificial corneal scaffolds that do not require donated cells or in vitro culture but instead will recruit the patient\u2019s own cells to regenerate the cornea post-implantation. These biomaterial scaffolds will incorporate specific chemical and physical cues with the deliberate aim of attracting cells and inducing tissue formation. Studies will be undertaken to examine how different chemical, biochemical, physical and mechanical cues can be used to control the behaviour of corneal epithelial, stromal and endothelial cells. Once the optimal combination of these cues has been determined, this information will be incorporated into the design of the scaffold. Recent advances in manufacturing and material processing technology will enable us to develop scaffolds with organized nanometric architectures and that incorporate controlled growth factor release mechanisms. Techniques such as 3D bio-printing and nanofiber electrospinning will be used to fabricate scaffolds. The ability of the scaffold to attract cells and promote matrix remodelling will be examined by developing an in vitro bioreactor system capable of mimicking the ocular environment and by performing in vivo tests using a live animal model.", "To": ["2020-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-07-01"], "Project_ID": ["637460"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN", "THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN"], "EU_Contribution": ["EUR 1 804 052"], "Project_Title": ["Targeting iNKT cell and adipocyte crosstalk for control of metabolism and body weight"], "Total_Cost": ["EUR 1 804 052"], "Country": ["Ireland", "Ireland"], "Project_ACR": ["FAT NKT"], "Technology_Description": "Obesity has reached epidemic proportions globally. At least 2.8 million people die each year as a result of being overweight or obese, the biggest burden being obesity-related diseases. It is now clear that inflammation is an underlying cause or contributor to many of these diseases, including type 2 diabetes, atherosclerosis, and cancer. Recognition that the immune system can regulate metabolic pathways has prompted a new way of thinking about diabetes and weight management. Despite much recent progress, most immunometabolic pathways, and how to target them, are currently unknown. One such pathway is the cross-talk between invariant natural killer (iNKT) cells and neighboring adipocytes. iNKT cells are the innate lipid-sensing arm of the immune system. Since our discovery that mammalian adipose tissue is enriched for iNKT cells, we have identified a critical role for iNKT cells in regulating adipose inflammation and body weight. The goal of this project is to use a multi-disciplinary approach to identify key signals and molecules used by iNKT cells to induce metabolic control and weight loss in obesity. Using immunological assays and multi-photon intravital microscopy, cells and pathways that control the unique regulatory functions of adipose iNKT cells will be identified and characterised. Novel lipid antigens in adipose tissue will be identified using a biochemical approach, perhaps explaining iNKT cell conservation in adipose depots, and providing safe tools for iNKT cell manipulation in vivo. Finally, using proteomics and whole body metabolic analysis in vivo, novel \u2018weight-loss inducing\u2019 factors produced by adipose iNKT cells will be identified. This ambitious and high impact project has the potential to yield major insights into immunometabolic interactions at steady state and in obesity. The ability to activate or induce adipose iNKT cells holds remarkable potential as an entirely new therapeutic direction for treating obesity and type 2 diabetes.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["679173"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["GENOME RESEARCH LIMITED", "GENOME RESEARCH LIMITED", "EUROPEAN MOLECULAR BIOLOGY LABORATORY"], "EU_Contribution": ["EUR 1 980 685"], "Project_Title": ["Re(defining) CD4+ T Cell Identities One Cell at a Time"], "Total_Cost": ["EUR 1 980 685"], "Country": ["United Kingdom", "United Kingdom", "Germany"], "Project_ACR": ["ThDEFINE"], "Technology_Description": "The immune system consists of a complex continuum of cell types that communicate with each other and non-immune tissues in homeostasis, and during infections, autoimmunity and cancer. Conventional transcriptional and functional profiling enabled by cell surface marker sorting has revealed a great deal about how specific cell types operate en masse, yet important transcriptional heterogeneity that exists within cell populations remains unexplored. High-throughput single cell RNA-seq can overcome this limitation by profiling entire transcriptomes of thousands of individual cells, revealing cell-to-cell variation by decoding patterns within populations masked in bulk transcriptomes. We will exploit this to dissect the mouse CD4+ T cell compartment, a heterogeneous white blood cell population that initiates adaptive immune responses.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-01-01"], "Project_ID": ["646794"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN"], "EU_Contribution": ["EUR 187 866"], "Project_Title": ["Historical Dynamics of Violence, Conflict and Extreme Weather in Medieval Ireland"], "Total_Cost": ["EUR 187 866"], "Country": ["Ireland"], "Project_ACR": ["CLIMCONFLICT"], "Technology_Description": "This project draws upon historical, palaeoclimatic, palaeoecological and archaeological records to examine the role of extreme weather in the occurrence of violence and conflict in medieval Ireland. The research is founded upon the Irish Annals, which preserve a detailed record of violence and conflict as chronicled by monastic scribes from the sixth to thirteenth centuries and, thereafter to the seventeenth century, by hereditary historians employed by the Irish nobility. The Irish oak tree-ring record provides a means of identifying years of extreme wetness and dryness, while Greenland ice-core records furnish evidence for major volcanic eruptions that often caused extreme cold. Combining these diverse sources affords an important opportunity to examine whether extreme weather meaningfully influenced violence and conflict in a complex agrarian society for over a millennium. To identify the mechanisms that may link extreme weather to violence and conflict, insights will be drawn from written sources such as the Irish law texts, hagiographical texts and bardic poetry. The rich record of weather extremes, societal impacts and coping mechanisms provided by the Irish Annals themselves will also be exploited. Climate-conflict linkages are also likely to be mediated by changing background socioeconomic and climatic conditions that promote varying societal resilience to extreme weather. Diverse palaeoclimatic, archaeological and palaeoecological evidence will thus be employed to track the often dramatic changes in Irish agricultural and military technology, in settlement and political structures, and in average precipitation and temperatures, experienced across this long period of Irish history.", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["709185"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN", "THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN"], "EU_Contribution": ["EUR 2 499 265"], "Project_Title": ["North Atlantic Fisheries: An Environmental History, 1400-1700"], "Total_Cost": ["EUR 2 499 265"], "Country": ["Ireland", "Ireland"], "Project_ACR": ["NorFish"], "Technology_Description": "NorFish aims to understand the restructuring of the North Atlantic fisheries, fish markets and fishery-dependent communities in the late medieval and early modern world. The project exploits a multi-disciplinary, humanities-led approach to marine environmental history, assessing and synthesizing the dynamics and significance of the North Atlantic fish revolution, equipped by methodological advances in which the PI has been to the fore in delivering. It establishes a robust quantitative framework of extractions, supplies and prices, while also charting the qualitative preferences and politics that motivated actors of the fish revolution across the North Atlantic. ", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["669461"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["UNIVERSIDAD DE LA LAGUNA", "UNIVERSIDAD DE LA LAGUNA"], "EU_Contribution": ["EUR 1 996 750"], "Project_Title": ["PALEOCHAR: Insights into the Neanderthals and their demise from the study of microscopic and molecular charred matter in Middle Palaeolithic sediments"], "Total_Cost": ["EUR 1 996 750"], "Country": ["Spain", "Spain"], "Project_ACR": ["PALEOCHAR"], "Technology_Description": "Who were the Neanderthals and what caused their demise? To answer these questions, the classic approach in archaeology relies on the analysis of the Neanderthals' stone-tool assemblages and the mineralized bone remains of their dietary intake. Although this approach has yielded a great deal of important information about the Neanderthals\u2019 fate, it is also limited in the sense that the only evidence that is considered is in-organic in nature. In the current proposal, we attempt to answer these questions by considering microscopic and molecular evidence that is organic in nature. By studying the organic sedimentary record at such fine scales, we are able to extract information about, for example, the fat contents of the Neanderthal food, the way they made fire, the arrangements of their living spaces, their surrounding vegetation and the climatic conditions where they lived. By combining these different sources of information we aim to provide a more complete picture of the Neanderthals and the reason of their disappearance. ", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["648871"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["UNIVERSIDAD REY JUAN CARLOS"], "EU_Contribution": ["EUR 239 191,20"], "Project_Title": ["Climatic and temporal control on microbial diversity-ecosystem functioning: insights from a novel conceptual model (CLIMIFUN)."], "Total_Cost": ["EUR 239 191,20"], "Country": ["Spain"], "Project_ACR": ["CLIMIFUN"], "Technology_Description": "Despite the importance of soil microbial communities for ecosystem functioning and human welfare, little is known about the mechanisms controlling the composition and diversity of these communities, and the role of their attributes in providing multiple ecosystem functions and services such as nutrient cycling and decomposition (i.e. multifunctionality). Many studies have identified climate, stage of ecosystem development and soil characteristics as main drivers of plant and animal diversity. However, much less is known about the interactive effects of climate, soil properties and time in controlling microbial diversity and multifunctionality during ecosystem succession. This lack of knowledge hampers our ability to predict microbial community shifts and their consequences for ecosystem functioning under climate change, and limits the inclusion of soil microbes in global biogeochemical models. The main research objective of this action is to gain a deeper insight into the patterns and mechanisms that drive soil microbial diversity and multifunctionality under changing environments. We will use a novel conceptual framework combining long-term chronosequences, climate change experiments and structural equation modelling to quantitatively evaluate the role of time, climate and multiple soil drivers in controlling microbial diversity and multifunctionality. The research outlined in this proposal includes a range of state-of-the-art biochemical, molecular and genomic methods for the analysis of microbial communities and multifunctionality that ensure the maximum utility and impact of our results. Altogether, CLIMIFUN will reveal the factors that control soil microbial diversity and multiple functions linked to plant production and nutrient cycling under a changing environment. This work will thus address a key knowledge gap relevant to supporting increases in global demand for food and fibre over the next decades, and a research priority for H2020.", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-08-01"], "Project_ID": ["702057"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN"], "EU_Contribution": ["EUR 175 866"], "Project_Title": ["Neuroscience and Narratives of Intimacy"], "Total_Cost": ["EUR 175 866"], "Country": ["Ireland"], "Project_ACR": ["NNI"], "Technology_Description": "As human beings, we tend to connect. Yet social isolation is a widespread condition with grave consequences on life-expectancy. Ideals of self-sufficiency and new modes of communication incite to isolate rather than attach. By contrast, experiencing meaningful intimate interactions has positive effects on health. But what is intimacy, where is it to be found, has it changed and how can it be studied?", "To": ["2018-05-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-05-15"], "Project_ID": ["705283"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSIDAD DE LA LAGUNA"], "EU_Contribution": ["EUR 251 276,40"], "Project_Title": ["Tracking past human impact on islands by improving palaeoecological reconstructions with PalEnDNA analysis"], "Total_Cost": ["EUR 251 276,40"], "Country": ["Spain"], "Project_ACR": ["ISLANDPALECO"], "Technology_Description": "Island ecosystems host a significant proportion of global biodiversity, but their rich insular biotas are also more vulnerable and less resistant to novel pressures than continental biotas. Human colonization has been a relatively recent event on most islands globally, and has nearly always resulted in devastating losses of biodiversity. The Canary Islands were no exception; these oceanic islands were colonized by aborigines more than 2000 years ago and later by Europeans, and have been transformed since this time. Despite being one of the most biodiverse regions within Europe and a target for EU biodiversity policies, there is a key knowledge gap about the pre-human state and natural variability of unmodified Canarian ecosystems that could help planners and managers to guide their strategies. This makes the Canaries the perfect place to reconstruct baseline ecosystem states and the long-term impacts of human activities. ISLANDPALECO will assess the timing and extent of human impact on Canary Island ecosystems by providing detailed reconstructions of past environments, combining leading edge and conventional palaeoecological tools and integrating the results in conservation ecology and management strategies. The project will provide new expertise in Canary Island palaeoenvironmental reconstructions through training the ER in the latest palaeoenvironmental DNA analysis (PalEnDNA) at the Landcare Research Long-Term Ecology Lab, one of the few labs in the world where this rapidly emerging field in palaeoecology is being applied to conservation on island settings. ISLANDPALECO will provide the ER with a new skill set in ancient molecular research that will be transferred to the University of La Laguna where they currently do not exist. This will be the first time that PalEnDNA analysis will be implemented in the Canaries and probably one of the few cases on islands, becoming a valuable benchmark example of the applicability of PalEnDNA analysis in other island regions.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["700952"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN"], "EU_Contribution": ["EUR 248 063,40"], "Project_Title": ["Use of novel techniques to identify pathogenic versus non-pathogenic TH17 cells in experimental autoimmune encephalomyelitis, a murine model of multiple sclerosis."], "Total_Cost": ["EUR 248 063,40"], "Country": ["Ireland"], "Project_ACR": ["DANTE"], "Technology_Description": "The aim of this Fellowship is for the researcher, Dr Karen Dixon, to receive advanced training, develop interdisciplinary skills with high-impact dissemination, and practical experience in line with a leading independent researcher in the EU. The remit of the Fellowship proposal falls under the category of Immunology- autoimmunity and TH17 cell biology. The researcher will be based for two years in the laboratory of Professor Vijay Kuchroo at Brigham & Women`s Hospital. The third year of the Fellowship will be completed in the Department of Biochemistry & Immunology, Trinity College Dublin (TCD) working under the supervision of Professor Kingston Mills. Research training will be implemented through an interdisciplinary project investigating the mechanism by which IL-23 regulates the development of pathogenic vs non-pathogenic TH17 cells. On the outgoing phase of the Fellowship, the researcher will access expertise, state-of-the-art training and mentoring in deciphering the heterogeneity of TH17 cells using advanced transcriptional analysis. In the return phase the researcher will consolidate the knowledge and experience gained in the US through further laboratory training in IL-17 mediated disease. In TCD she will be given the opportunity to embed her new knowledge in Ireland through mentoring and teaching in the host institute. This includes practical seminars on state of the art technology including single cell RNA-seq and NanoString technology. Under the guidance of international experts, she will acquire an invaluable skillset using the latest technical advances to decode heterogeneous populations in immune mediated diseases. The resources of the host departments will facilitate development of an interdisciplinary and international academic network as well as career-mentoring. With increasing recognition of the functional heterogeneity within cell populations, this Fellowship will establish the researcher firmly at the centre of immunological research in the EU.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["708658"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN"], "EU_Contribution": ["EUR 248 063,40"], "Project_Title": ["Segregated education in post-conflict Bosnia and the possibilities of future conflicts in Europe"], "Total_Cost": ["EUR 248 063,40"], "Country": ["Ireland"], "Project_ACR": ["GATED"], "Technology_Description": "The aim of this Fellowship is to provide Dr Maja Halilovic-Pastuovic with advanced interdisciplinary training and new skills and experience in order to enhance her innovative and creative potential, increase her knowledge base, expand her career possibilities and enable her to reach professional maturity commensurate with a leading researcher in the EU. The remit of the Fellowship falls under the categories of transformation of societies, interethnic relations, and education: systems and institutions. The researcher will be based for two years at the Josef Korbel School, University of Denver, working under the supervision of Professor Timothy Sisk. The return phase of the Fellowship will be completed in the Irish School of Ecumenics at Trinity College Dublin under the supervision of Prof Etain Tannam. Research training will be implemented through an interdisciplinary project investigating segregated education in Bosnia and Herzegovina and security in Europe. The specific aim of the project is to investigate if segregated education in post-conflict societies causes radicalisation of youth and increases the possibilities of future conflicts. The Researcher is a trained sociologist and the exposure to the University of Denver whose expertise lies in the field of international relations and political science, and to Trinity College Dublin where expertise is focused on peace studies, will provide the researcher with interdisciplinary training necessary for advancement of her career and the success of the project. The resources of the two host institutions will facilitate the development of an international academic network, as well as career mentoring, and will firmly establish the researcher at the centre of the transnational interdisciplinary nexus addressing the challenge of European security.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["708249"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN", "AALBORG UNIVERSITET", "FLOATING POWER PLANT A/S"], "EU_Contribution": ["EUR 845 838,36"], "Project_Title": ["European Industrial DoCtorate on Offshore WiNd and Wave ENergy"], "Total_Cost": ["EUR 845 838,36"], "Country": ["Ireland", "Denmark", "Denmark"], "Project_ACR": ["ICONN"], "Technology_Description": "ICONN is a unique European Industrial Doctorate initiative to meet the current and future demand for highly skilled offshore wind and wave energy engineers by developing and advancing European capacity in the design, development and performance optimisation for Offshore Wind and Wave Energy installations. The initiative is strongly shaped by active participation from industries, and will develop and enhance European capacity in the offshore renewable energy area at a critical juncture in time when Europe strives to occupy a lead market position globally in this sector.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-EID - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-EID)"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-10-01"], "Project_ID": ["675659"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN"], "EU_Contribution": ["EUR 175 866"], "Project_Title": ["High-Resolution X-ray Structures of Full-Length Cystic Fibrosis Transmembrane Conductance Regulator"], "Total_Cost": ["EUR 175 866"], "Country": ["Ireland"], "Project_ACR": ["CF_struct"], "Technology_Description": "This proposal seeks to solve the high-resolution X-ray crystal structure of full-length Cystic Fibrosis Transmembrane Conductance Regulator (CFTR), an anion channel which regulates chloride ion concentration at the lumen-exposed surface of epithelial cells. Mutations of the CFTR gene cause cystic fibrosis (CF), a lethal disease which results in bowel obstruction, lung disease and premature death. CFTR is an ATPase and a member of the ATP-Binding Cassette (ABC) transporter family of proteins which has an allosteric Regulatory (R) domain not found in other ABC transporters. From the structure of CFTR, its mode of action will be revealed, focusing on the two sites of ATP hydrolysis and key residues for channel gating. CFTR will be crystallized alone and in the presence of the pharmacological agent Kalydeco, a small molecule from Vertex Pharmaceuticals that is used for the treatment of CF and reduces CF symptoms. The initial high-resolution X-ray crystal structure is a foundation from which personalized drug design work can begin. Therefore, the Kalydeco-CFTR complex structure will be used for ligand optimization of Kalydeco, an iterative process which will improve Kalydeco\u2019s specificity and pharmacokinetics. The latest technology, including in meso in situ serial crystallography and X-ray free electron lasers for serial femtosecond crystallography will be used as well as traditional synchrotron X-ray sources. These Actions use an interdisciplinary mix of crystallography, chemistry, biochemistry, biophysics and computational structural determination programs. The work will take place in Ireland in the lab of Dr. Martin Caffrey at Trinity College Dublin, a distinguished researcher in the field of membrane structural and functional biology. The prestigious Marie Sk\u0142odowska-Curie fellowship will enable the candidate to actualize many objectives outlined in her career development plan in order to become an independent researcher.", "To": ["2018-11-15, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-11-16"], "Project_ID": ["704848"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSIDAD DE LA LAGUNA", "UNIVERSIDAD DE LA LAGUNA"], "EU_Contribution": ["EUR 1 999 742"], "Project_Title": ["Optoelectrical Dynamics of Ion channel Activation in Calcium Nanodomains"], "Total_Cost": ["EUR 1 999 742"], "Country": ["Spain", "Spain"], "Project_ACR": ["NANOPDICS"], "Technology_Description": "In neurons, sites of Ca2+ influx and Ca2+ sensors are located within 20-50 nm, in subcellular \u201cCa2+ nanodomains\u201d. Such tight coupling is crucial for the functional properties of synapses and neuronal excitability. Two key players act together in nanodomains, coupling Ca2+ signal to membrane potential: the voltage-dependent Ca2+ channels (VDCC) and the large conductance Ca2+ and voltage-gated K+ channels (BK). BK channels are characterized by synergistic activation by Ca2+ and membrane depolarization, but the complex molecular mechanism underlying channel function is not adequately understood. Information about the pore region, voltage sensing domain or isolated intracellular domains has been obtained separately using electrophysiology, biochemistry and crystallography. Nevertheless, the specialized behavior of this channel must be studied in the whole protein complex at the membrane in order to determine the complete range of structures and movements critical to its in vivo function. Using a combination of genetics, electrophysiology and spectroscopy, our group has measured for the first time the structural rearrangements accompanying whole BK channel activation at the membrane. From this unique position, our first goal is to fully determine the real time structural dynamics underlying the molecular coupling of Ca2+, voltage and activation of BK channels in the membrane environment, its regulation by accessory subunits and channel effectors.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["648936"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["GEORG-AUGUST-UNIVERSITAT GOTTINGENSTIFTUNG OFFENTLICHEN RECHTS", "GEORG-AUGUST-UNIVERSITAT GOTTINGENSTIFTUNG OFFENTLICHEN RECHTS", "KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 1 901 427,84"], "Project_Title": ["Weight metrology and its economic and social impact on Bronze Age Europe, West and South Asia"], "Total_Cost": ["EUR 1 901 427,84"], "Country": ["Germany", "Germany", "Denmark"], "Project_ACR": ["WEIGHTANDVALUE"], "Technology_Description": "This project explores the economical and societal transformations provoked by weights and measures during the Bronze Age in Western Eurasia. The impact and significance of weight-based measures for value assessments during the Bronze Age is largely unknown und understudied. My objective is to unravel this empirical and intellectual gap in studies of the prehistoric and ancient economy. The project will uncover new sources for the reconstruction of trade and exchange networks due to the identification of a mostly overlooked or ignored class of artefacts: early balance weights. This opens up a new understanding of the nature and extent of the earliest commercial economies in the world. The ambitious project aims to document for the first time potential weights, often of unexpected simple shape, as well as canonical weights, frequently not sufficiently documented in a selection of cases studies between the Atlantic and the Indus. Further focus will be on potential mass-related finished metal objects, standardization and pre-coinage currencies, contributing to the debate on the origins of money. Specific statistical methods and 3D scanning provide a novel tool package to verify assumptions in a rigorous way. Hypotheses to be tested include identifying the potential correlation of the emergence of weight metrology to elucidating the first extensive trade in raw material (like silver, tin), the connection of weights to other administrative and commercial tools like seals and script, and their impact of early conceptions of value. The early dissemination of weights and weighing systems will be analysed systematically on evidence from the Bronze Age in Western Eurasia. The proposed research starts with identifying and documenting potential balance weights and mass related objects by archaeological indications and the rigorous application of various statistical methods, but progresses to developing and testing models of exchange and transfer of innovations.", "To": ["2020-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-08-01"], "Project_ID": ["648055"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN", "THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN"], "EU_Contribution": ["EUR 2 499 942"], "Project_Title": ["3D Printing of Novel 2D Nanomaterials: Adding Advanced 2D Functionalities to Revolutionary Tailored 3D Manufacturing"], "Total_Cost": ["EUR 2 499 942"], "Country": ["Ireland", "Ireland"], "Project_ACR": ["3D2DPrint"], "Technology_Description": "My vision is to establish, within the framework of an ERC CoG, a multidisciplinary group which will work in concert towards pioneering the integration of novel 2-Dimensional nanomaterials with novel additive fabrication techniques to develop a unique class of energy storage devices.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["681544"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN", "THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN"], "EU_Contribution": ["EUR 1 999 700"], "Project_Title": ["3D Printing of Cell Laden Biomimetic Materials and Biomolecules for Joint Regeneration"], "Total_Cost": ["EUR 1 999 700"], "Country": ["Ireland", "Ireland"], "Project_ACR": ["JointPrinting"], "Technology_Description": "Osteoarthritis (OA) is a serious disease of the joints affecting nearly 10% of the population worldwide. Realising an efficacious therapeutic solution for treating OA remains one of the greatest challenges in the field of orthopaedic medicine. This proposal envisions a future where 3D bioprinting systems located in hospitals will provide \u2018off-the-shelf\u2019, patient-specific biological implants to treat diseases such as OA. To realise this vision, this project will use 3D bioprinting to generate anatomically accurate, biomimetic constructs that can be used to regenerate both the cartilage and bone in a diseased joint. The first aim of this proposal is to print a mesenchymal stem cell laden biomaterial that is both immediately load bearing and can facilitate the regeneration of articular cartilage in vivo, such that the bioprinted construct will not require in vitro maturation prior to implantation. Mechanical function will be realised by integrating an interpenetrating network hydrogel into a 3D printed polymeric scaffold, while chondro-inductivity will be enhanced by the spatially-defined incorporation of cartilage extracellular matrix components and chondrogenic growth factors into the bioprinted construct. The second aim of the proposal is to use 3D bioprinting to create a cell-free, composite construct to facilitate regeneration of the bony region of a large osteochondral defect, where vascularization will be accelerated by immobilizing spatial gradients of vascular endothelial growth factor into the implant. The third aim of the proposal is to scale-up the proposed 3D bioprinted construct to enable whole joint regeneration. Finite element modelling will be used determine the optimal structural characteristics of the scaled-up implant for it to fulfil its required mechanical function. If successful, such an implant would form the basis of a truly transformative therapy for treating degenerative joint disease.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["647004"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN", "THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN"], "EU_Contribution": ["EUR 1 979 366"], "Project_Title": ["Towards Artificial Enzymes: Bio-inspired Oxidations in Photoactive Metal-Organic Frameworks"], "Total_Cost": ["EUR 1 979 366"], "Country": ["Ireland", "Ireland"], "Project_ACR": ["Supramol"], "Technology_Description": "Metal-organic frameworks (MOFs) are key compounds related to energy storage and conversion, as their unprecedented surface areas make them promising materials for gas storage and catalysis purposes. We believe that their modular construction principles allow the replication of key features of natural enzymes thus demonstrating how cavity size, shape, charge and functional group availability influence the performances in catalytic reactions. This proposal addresses the question of how such novel, bio-inspired metallo-supramolecular systems can be prepared and exploited for sustainable energy applications. A scientific breakthrough that demonstrates the efficient conversion of light into chemical energy would be one of the greatest scientific achievements with unprecedented impact to future generations. We focus on the following key aspects:", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["647719"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN", "THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN"], "EU_Contribution": ["EUR 149 774"], "Project_Title": ["Ink-Jet printed supercapacitors based on 2D nanomaterials."], "Total_Cost": ["EUR 149 774"], "Country": ["Ireland", "Ireland"], "Project_ACR": ["2D-Ink"], "Technology_Description": "This proposal will determine the technical-economic viability of scaling-up ultra-thin, ink-jet printed films based on liquid-phase exfoliated single atomic layers of a range of nanomaterials. The PI has developed methods to produce in liquid nanosheets of a range of layered materials such as graphene, transition metal oxides, etc. These 2D-materials have immediate and far-reaching potential in several high-impact technological applications such as microelectronics, composites and energy harvesting and storage. 2DNanoCaps (ERC ref: 278516) has demonstrated that lab-scale ultra-thin graphene-based supercapacitor electrodes result in unusually high-power and extremely long device life-time (100% capacitance retention for 5000 charge-discharge cycles at the high power scan rate of 10,000 mV/s). This performance is an order of magnitude better than similar systems produced with conventional methods which cause materials restacking and aggregation. A following ERC PoC grant (2D-USD, Project-Number 620189) is currently focussed on up-scaling the production of thin-films deposition methods based on ultrasonic spray for the production of large-area electrodes for supercapacitors applications. In this proposal we want to explore the new concept of manufacturing conductive, robust, thin, easily assembled electrode and solid electrolytes to realize highly-flexible and all-solid-state supercapacitors by ink-jet printing. This opportunity is particularly relevant to the electronics and portable-device industry and offers the possibility to solve flammability issues, maintaining light weight, flexibility, transparency and portability. In order to do so it will be imperative to develop ink-jet printing methods and techniques. We believe our combination of unique materials and cost-effective, robust and production-scalable process of ultra- thin ink-jet printing will enable us to compete for significant global market opportunities in the energy-storage space.", "To": ["2016-09-30, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2014 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-04-01"], "Project_ID": ["665674"], "Call_for_Proposal": ["ERC-2014-PoC"]}, -{"Partners": ["UNIVERSIDAD REY JUAN CARLOS"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["PhotoCloth: A framework to synthesize real-time photorealistic cloth animation from video input."], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["PhotoCloth"], "Technology_Description": "Computer Graphics is the area of computer science that studies methods for digitally synthesizing and animating visual content. Among all the potential contexts where computer graphics techniques can be used, cloth animation is a particularly interesting case since, in the real world, clothing is far more than just the physical objects that we wear; clothing is a key element to show someone\u2019s expressiveness and motion, it even defines his or her identity. ", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["707326"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN"], "EU_Contribution": ["EUR 175 866"], "Project_Title": ["MULTImodal and MULTIparty Social Interactions MOdelling"], "Total_Cost": ["EUR 175 866"], "Country": ["Ireland"], "Project_ACR": ["MULTISIMO"], "Technology_Description": "The project addresses the modelling of multimodal communicative human behaviour during natural interactions in multiparty settings and specifically the conversational and feedback strategies of the interaction participants in terms of attention, engagement and conflict management. The knowledge base for this modelling problem will be a collection of human-human interaction recordings to be acquired through a concise experimental protocol and state-of-the-art equipment. The communicative behavior will be analysed in multimodal signals, including facial expressions, gaze and prosodic cues that provide information about social interaction management and speakers\u2019 attitudes. This information becomes more complex in group interactions, where a management mechanism will be discovered and modelled. These low-level signals will be examined in relation to their timing and sequence to infer and model high-level signals of attention, engagement and conflict, and subsequently implement modules to feed existing HCI interfaces such as dialogue systems or avatars. The implementation of such novel models will allow for the creation of more sophisticated human-like agent-based interfaces of high quality communication experience, especially in scenarios where social and cognitive skills, in addition to the communicative ones, are crucial for the success of the interaction, i.e. in the education, customer care domains and web applications requiring interfaces triggered by human communication. The project builds on the strengths of the applicant in multimodal communication and language technology, and combines these with new training in intelligent systems and human-computer interaction to support a new research direction and to strengthen cross-European collaboration. The host provides an excellent supportive environment conducive to the interdisciplinary research envisaged in the project and the training objectives of the fellowship in view of the applicant\u2019s career development.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["701621"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITAT ZU LUBECK", "UNIWERSYTET IM. ADAMA MICKIEWICZA W POZNANIU", "DET KONGELIGE DANSKE KUNSTAKADEMIS SKOLER FOR ARKITEKTUR, DESIGN OG KONSERVERING.", "CYBERTRONICA UG (HAFTUNGSBESCHRANKT) GMBH", "IT-UNIVERSITETET I KOBENHAVN", "UNIVERSITAET GRAZ", "UNIVERSITAET PADERBORN"], "EU_Contribution": ["EUR 3 641 781"], "Project_Title": ["Flora Robotica: Societies of Symbiotic Robot-Plant Bio-Hybrids as Social Architectural Artifacts"], "Total_Cost": ["EUR 3 641 782,50"], "Country": ["Germany", "Poland", "Denmark", "Germany", "Denmark", "Austria", "Germany"], "Project_ACR": ["flora robotica"], "Technology_Description": "This project's objective is to develop and to investigate closely linked symbiotic relationships between robots and natural plants and to explore the potentials of a plant-robot society able to produce architectural artifacts and living spaces. We will create a society of robot-plant bio-hybrids functioning as an embodied, self-organizing, and distributed cognitive system. The system grows and develops over long periods of time in interactions with humans resulting in the creation of meaningful architectural structures. The robotic assemblies (\u2018artificial plants\u2019) support and control the biological plants through appropriate scaffolding, watering, and stimuli that exploit the plants\u2019 different tropisms. The natural plant, in turn, supports and controls the robotic plant by guiding it through growth and support the weight of the robot in later growth phases. The artificial plants are built from small heterogeneous sensing and actuation modules connected using lightweight construction elements. Each robotic plant connects wirelessly to the Internet. In contrast to top-down control, we explore a developmental plasticity of bio-hybrid systems, where robots and plans grow together from sprout to adult stage and form a closely co-dependent and self-organized system. The robot-plant organisms live in a human-inhabited environment and through interaction with humans grow into architectural structures (e.g., walls, roofs, benches) providing functionality such as shade, air quality control, and stress relief. Humans, plants, and robots form an internet-connected social garden where desired structures and behavior patterns emerge based on both local interactions and global interaction with parts of the garden growing at other locations. Hence, the social garden is a cultural system that shows long-term learning and adaptation where all past actions and interactions between the natural and artificial plants are represented in the embodiment of the garden.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["FETPROACT-2-2014 - Knowing, doing, being: cognition beyond problem solving"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-04-01"], "Project_ID": ["640959"], "Call_for_Proposal": ["H2020-FETPROACT-2014"]}, -{"Partners": ["TECHNISCHE UNIVERSITEIT DELFT", "THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN", "STICHTING WAAG SOCIETY", "ARTSHARE INVESTIGACAO TECNOLOGIA EARTE LDA", "FONDAZIONE SANTA LUCIA", "T.S.R.ACT SRO"], "EU_Contribution": ["EUR 549 727"], "Project_Title": ["BrainHack: Bringing the arts and sciences of brain and neural computer interface together"], "Total_Cost": ["EUR 549 727"], "Country": ["Netherlands", "Ireland", "Netherlands", "Portugal", "Italy", "Czech Republic"], "Project_ACR": ["BrainHack"], "Technology_Description": "We witness a rapid development of Brain/Neural Computer Interaction (BNCI) research including hyperscanning and collaborative BNCIs. Several recent BNCI community driven CSAs have addressed this topic (Future BNCI, BNCI Horizon 2020 ) with the BCI Society being in progress of establishing. At the same time, a growing community of international artists is exploring the boundaries of brain physiology based interaction in cinema, theatre and interactive installations. Artists address questions of BNCI ethics and aesthetics which are often overlooked by scientists but which spur general public discussion. ", "To": ["2017-12-31, closed project |"], "Meta": [""], "Topic_s": ["FETOPEN-3-2015 - Coordination and Support Activities"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-01-01"], "Project_ID": ["686987"], "Call_for_Proposal": ["H2020-FETOPEN-2015-CSA"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN"], "EU_Contribution": ["EUR 266 063,40"], "Project_Title": ["'Science as Applied to Building' : Science, Construction, and Architectural Acoustics (1914-1954)"], "Total_Cost": ["EUR 266 063,40"], "Country": ["Ireland"], "Project_ACR": ["SAAB"], "Technology_Description": "The aim of this Fellowship is for the researcher, Dr Fiona Smyth, to develop the professional prowess, advanced training, interdisciplinary skills, high-impact dissemination, and practical experience commensurate with a leading independent researcher in the EU. The remit of the Fellowship research falls under the categories of history of science, history of construction and architectural acoustics. The researcher will be based for two years in the Dept. of the History of Science in Harvard University, working under the supervision of Professor Peter Galison. The third year of the Fellowship will be completed in the Acoustics Research Group in the School of Engineering, Trinity College Dublin (TCD) working under the supervision of Professor Henry Rice. Research training will be implemented through an interdisciplinary project investigating the 20th century emergence of architectural acoustics as a branch of modern building science in Britain and Ireland. On the outgoing phase of the Fellowship the researcher will access expertise, advanced training and mentoring in the History of Science. No Irish university has yet established a dedicated History of Science department. In the return phase the researcher will consolidate the knowledge and experience gained in the US through advanced laboratory training in acoustics. In TCD she will be given the opportunity to embed her new knowledge in the design of interdisciplinary curricula for graduate students. Under the guidance of international experts, she will acquire an invaluable skill-set bridging humanities, science and technology with implications for contemporary societal and economic application. The resources of the host departments will facilitate development of an interdisciplinary and international academic network as well as career mentoring. The Fellowship will establish the researcher firmly at the centre of interdisciplinary research in the histories of building science and architectural acoustics.", "To": ["2018-06-30, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-07-01"], "Project_ID": ["654796"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSIDAD REY JUAN CARLOS", "UNIVERSIDAD REY JUAN CARLOS"], "EU_Contribution": ["EUR 149 545"], "Project_Title": ["Computer-Aided Fashion with Yarn-Level Fabric Models"], "Total_Cost": ["EUR 149 545"], "Country": ["Spain", "Spain"], "Project_ACR": ["FabricMetrics"], "Technology_Description": "The Animetrics ERC Starting Grant has led to the invention of the first computer models capable of simulating in an accurate, efficient and robust manner the behavior of full textiles using a yarn-level representation. The proposed models handle frictional yarn interactions at the small scale, yet they naturally produce the rich large-scale nonlinearity of textiles. In contrast, models used in the fashion, engineering, or VFX industries nowadays, describe textiles as a continuum, and do not reach the accuracy required for validating the mechanical behavior and visual appearance of cloth.", "To": ["2018-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2015 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["713742"], "Call_for_Proposal": ["ERC-2015-PoC"]}, -{"Partners": ["UNIVERSIDAD REY JUAN CARLOS"], "EU_Contribution": ["EUR 201 726"], "Project_Title": ["Vulnerability of soil organic carbon to climate change in permafrost and dryland ecosystems"], "Total_Cost": ["EUR 201 726"], "Country": ["Spain"], "Project_ACR": ["VULCAN"], "Technology_Description": "Soil organic matter provides essential ecosystem services and is one of the largest C reservoirs on Earth, holding more than three-fold as much C as does the atmosphere. Over 75% of the global soil organic C pool is stored in permafrost and dryland regions, both under high pressure due to climate change. In particular, global warming may accelerate soil organic matter decomposition in these ecosystems, which may dramatically endanger their functioning and worsen climate change by releasing significant amounts of CO2 to the atmosphere. However, the rate of this effect and to what extent it may be offset by warming-induced increases of plant-derived organic inputs remain highly uncertain. The main objective of this project is to gain a deeper insight into the vulnerability of soil organic matter to climate change in permafrost and drylands, and to explore potential implications in terms of ecosystem functioning and feedback to global warming. We will use globally unique ecosystem warming experiments in Alaska (permafrost) and central Spain (dryland), with a well-established monitoring of plant productivity, phenology, and nutrient status, soil physical, chemical, biochemical, and microbiological properties, and CO2 fluxes. We will focus on the destabilization, stabilization, and transformation processes of soil organic matter at the molecular level by using an unparalleled combination of state-of-the-art methods for soil organic matter fractionation into pools directly related to conceptual preservation mechanisms, powerful stable and radioactive isotope techniques, and advanced nuclear magnetic resonance tools. VULCAN will fill major gaps in our knowledge, will make this information widely available to scientists, policy makers, and the general public, and will provide the Fellow with the necessary knowledge, skills, networking, and experience to lead future research projects related to the feedbacks between climate change and terrestrial ecosystems in Europe.", "To": ["2018-06-30, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-07-01"], "Project_ID": ["654132"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA", "AZ.OSP.-UNIV.S.M.MISERICORDIA DI UDINE", "UNIVERSITY OF LINCOLN"], "EU_Contribution": ["EUR 441 000"], "Project_Title": ["Nanostructured molecular decoders for the quantitative, multiplexed, layer-by-layer detection of disease-associated proteins"], "Total_Cost": ["EUR 441 000"], "Country": ["Italy", "Italy", "United Kingdom"], "Project_ACR": ["Immuno-NanoDecoder"], "Technology_Description": "The long-range goal of this project is to develop a molecular nanodevice, based on nucleic acid-protein conjugates, for the multiplexed, quantitative imaging of biomarkers in tissue samples and cultured cells.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2015-04-01"], "Project_ID": ["645684"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN"], "EU_Contribution": ["EUR 175 162,50"], "Project_Title": ["Discover Research Dublin - European Researchers' Night 2014/2015"], "Total_Cost": ["EUR 175 162,50"], "Country": ["Ireland"], "Project_ACR": ["DiscoverResearch"], "Technology_Description": "Ireland\u2019s leading university, Trinity College Dublin (TCD), in partnership with the Royal College of Surgeons in Ireland (RCSI), is seeking funding to plan, promote and host Discover Research Night as part of European Researchers\u2019 Night in 2014 and 2015. On Discover Research Night 26 September 2014 and 25 September 2015, TCD and RCSI will offer the general public a wide range of interactive and hands-on activities, providing direct contact with researchers and allowing for discovery, questions and participation. The objectives of the project are to challenge perceptions held by the general public about researchers, to promote research as an exciting career option, to demonstrate creativity and innovation in research across all disciplines and to show that researchers are dynamic contributors to society. Interaction with researchers during EU Researchers\u2019 Night will challenge stereotypes which have created barriers between the general public and researchers. Specific career-focused events will identify and promote arrays of opportunities for research careers. Diverse activities which will help to show the public how research benefits the community. Events will showcase exciting innovative research from several academic strands at TCD and RCSI, will invite the public to interact with the vibrant research communities from both participating institutes, aiming to delight and stimulate the imagination of all participants from school children and their families, to visitors to Dublin and the local community. Activities hosted on the night will be grouped under four broad themes \u2013 Body Parts including \u2018Discover the Brain!\u2019, \u2018Mending Broken Hearts, \u2018Attack of the Heart\u2019; Language, Thought & Knowledge Transfer including \u2018Identities in Transformation\u2019, \u2018Living Thought/Thinking Life\u2019, \u2018Tower of Babel\u2019, Creativity in Research featuring \u2018Biodiversity in our Lives\u2019 and Meet the Researchers including \u2018Thesis-in-3\u2019, \u2018Innovation Caf\u00e9\u2019, \u2018Women in Science\u2019 and \u2018Career Clinic\u2019.", "To": ["2015-11-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-NIGHT-2014 - European Researchers' Night (NIGHT)"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2014-06-01"], "Project_ID": ["633292"], "Call_for_Proposal": ["H2020-MSCA-NIGHT-2014"]}, -{"Partners": ["THE QUEEN'S UNIVERSITY OF BELFAST"], "EU_Contribution": ["EUR 1 569 600"], "Project_Title": ["Supporting Pioneer doctoral Researchers through 3i Knowledge partnerships"], "Total_Cost": ["EUR 3 139 200"], "Country": ["United Kingdom"], "Project_ACR": ["SPARK"], "Technology_Description": "The SPaRK Programme is driven by the need to develop future leaders whose skills combine disciplinary excellence with a capacity for interdisciplinary and intersectoral working that creates genuinely disruptive thinkers. SPaRK recognises that genuinely game-changing intersectoral, international and interdisciplinary collaboration does not happen simply by making available opportunities for mobility, placements, or input from other disciplines. It is therefore designed to offer an innovative model of professional and scientific development that is proactively training researchers to be able to maximise the potential of these 3i partnerships. Only by rethinking our current, competence-based skills agenda in ways that embrace a model based on intellectual flexibility and creativity can we prepare the leaders who will be equipped to respond to constantly shifting global challenges. The SPaRK programme thus proposes the integration of disciplinary excellence with a meaningful reflection on the possibilities both of interdisciplinarity and of mobility across cultural, linguistic, professional and epistemological borders.", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2016 - Co-funding of regional, national and international programmes"], "Funding_scheme": ["MSCA-COFUND-DP - Doctoral programmes"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["754507"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 99 775"], "Project_Title": ["Wavelength tunable Advanced Single Photon Sources Non-laboratory Environment Specification and Testing"], "Total_Cost": ["EUR 99 775"], "Country": ["United Kingdom"], "Project_ACR": ["WASPSNEST"], "Technology_Description": "Triggered single photon sources are key enabling tools in the new technology of quantum communications and a host of quantum optics research, but have not found widespread use because robust and portable devices have yet to be commercialised. The FP7 WASPS project is completing laboratory-based demonstrator experiments for a new range of plug-in single photon sources that can ultimately be operated at ambient temperatures and in non-laboratory environments. The devices, based on nitrogen-vacancy colour centres in diamond coupled to optical microcavities, offer a degree of wavelength tunability and a flexible design in which the active component can be replaced and upgraded. Work towards construction of a field-testable prototype device has started. In this Innovation Launchpad project, we propose to carry out critical steps in the development and field testing of this prototype that will provide key performance information to companies looking to manufacture and market the technology. These will involve innovative refinement of the active module containing the cavity and single photon emitter, development of module assembly protocols compatible with manufacturing, and testing of the prototype in a free-space quantum key distribution system. The project will bring robust triggered single photon sources closer to market and will promote innovation and entrepreneurship within the H2020 FET programme.", "To": ["2018-05-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-04-2016-2017 - FET Innovation Launchpad"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["754509"], "Call_for_Proposal": ["H2020-FETOPEN-4-2016-2017"]}, -{"Partners": ["ALBERT-LUDWIGS-UNIVERSITAET FREIBURG"], "EU_Contribution": ["EUR 2 371 800"], "Project_Title": ["FRIAS COFUND Fellowship Programme for Junior and Senior Researchers - Phase 2"], "Total_Cost": ["EUR 4 743 600"], "Country": ["Germany"], "Project_ACR": ["FCFP"], "Technology_Description": "The Freiburg Institute for Advanced Studies (FRIAS) is an internationally renowned university-based institute for advanced studies that offers time-limited fellowship stays for excellent junior and senior researchers from around the world. The Institute is part of the University of Freiburg, one of the leading research universities in Europe. ", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2016 - Co-funding of regional, national and international programmes"], "Funding_scheme": ["MSCA-COFUND-FP - Fellowship programmes"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["754340"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2016"]}, -{"Partners": ["FUNDACAO D. ANNA SOMMER CHAMPALIMAUD E DR. CARLOS MONTEZ CHAMPALIMAUD"], "EU_Contribution": ["EUR 148 635,60"], "Project_Title": ["Functional role of neuronal spontaneous activity for sensory processing"], "Total_Cost": ["EUR 148 635,60"], "Country": ["Portugal"], "Project_ACR": ["Spontaneous activity"], "Technology_Description": "Understanding how the brain processes sensory stimuli to guide behavior is still an unresolved mystery in neuroscience. The view that behavior may be passively guided by the senses is challenged by the observation that the brain is always spontaneous active. Even cortical areas that are supposed to represent features of the sensory environment manifest spontaneous activity (SA) in the absence of external inputs. The similarity between SA and sensory-evoked activity (EA) has been interpreted as learning of features of the external world by cortical circuits. However, the mechanism by which SA affects brain computation is largely unknown. In this proposal we aim at elucidating the functional role of SA for processing of sensory information in the auditory modality. We will take advantage of state-of-the-art tools available in mice to modulate and record the activity of large populations of neurons across cortical layers. Mice will be trained to perform frequency (or location) discrimination tasks and expectation will be generated by using trials in blocks in which the sound location (or frequency) probability will vary. We hypothesize that the induced expectation will facilitate sensory discrimination and manifest as specific patterns of SA before stimulus presentation. We will then manipulate optogenetically auditory cortex to causally test the role of SA in the task. Finally, we will record the simultaneous activity of a large number of neurons to understand mechanistically how SA may affects the processing of incoming sensory stimuli. Our study has the potential to uncover new neuronal mechanisms underlying sensory processing.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Portugal"], "Activity": ["Research Organisations"], "From": ["2018-09-01"], "Project_ID": ["753819"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["AGENCE NATIONALE DE SECURITE SANITAIRE DE L'ALIMENTATION, DE L'ENVIRONNEMENT ET DU TRAVAIL"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Multi-approach determination of metal based pesticides in food"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["MET-PEST"], "Technology_Description": "The industrial and agricultural activities of the modern society lead to significant release of a large number of toxic substances into the environment having an ultimate impact on the food quality and human health. Many of such chemicals are used in agriculture as pesticides, fungicides, etc. to enhance the productivity. This is the case of dithiocarbamates (DTC) that are one of the relatively large used fungicides being effective against a broad spectrum of fungi and plant diseases. Despite the significant environmental and food chain impact of DTC, the current analytical approaches for their determination suffer from serious drawbacks. The European reference method for this purpose relies on non-selective quantification by indirect determination of the sum of DTC species hence this approach provides incomplete information on the exposure to individual DTC. The present proposal aims at the development and validation of a method for accurate and selective determination of DTCs in food by a multi-approach strategy. A combination of analytical methodologies such as those currently employed for trace metals speciation and also for organic contaminants will be developed and fully validated. These methodologies will be critically compared through the analysis of real-life food samples from EU and imported from external markets. The impact of different cooking modes on DTC degradation pathways will also be investigated. By combining powerful separation techniques such as high performance liquid chromatography with elemental and molecular spectrometry, this project will allow obtaining a deeper knowledge on the presence of individual DTCs in various foodstuff and of their degradation mechanisms during food processing. Additionally, it will consistently contribute to the development of a reference method for selective DTC determination in food hence having a great impact on the scientific research in food quality control at European level.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2017-10-01"], "Project_ID": ["753053"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSIDADE DA CORUNA", "HELSINGIN YLIOPISTO", "INESC ID - INSTITUTO DE ENGENHARIADE SISTEMAS E COMPUTADORES, INVESTIGACAO E DESENVOLVIMENTO EM LISBOA", "ENXENIO SL"], "EU_Contribution": ["EUR 648 000"], "Project_Title": ["Bioinformatics and Information Retrieval Data Structures Analysis and Design"], "Total_Cost": ["EUR 648 000"], "Country": ["Spain", "Finland", "Portugal", "Spain"], "Project_ACR": ["BIRDS"], "Technology_Description": "Nowadays computers are used to process huge amounts of information, for example a major search engine processes tens of thousands of searches per second. Still the future of the information age is at risk. Computer architectures will not be resilient enough for the next information challenges. It is not only a matter of word size or clock cycles. New DNA sequencing technologies are evolving much faster than Moore's law, this means that they are evolving faster than the amount of transistors that go into CPUs and GPUs. Moreover computer disks are, by far, the slowest part of the architecture and are evolving even slower, therefore widening the relative time that information takes to reach the processor.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-01-01"], "Project_ID": ["690941"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["UNIVERSIDAD DE BURGOS", "UNIVERSITA DEGLI STUDI DEL PIEMONTE ORIENTALE AMEDEO AVOGADRO", "THE UNIVERSITY OF BIRMINGHAM", "BIONANONET FORSCHUNGSGESELLSCHAFT MBH", "Research and Development of Carbon Nanotubes S.A.", "SITEX 45 SRL", "NOVAMECHANICS LIMITED", "NANOTECHNOLOGY INDUSTRIES ASSOCIATION"], "EU_Contribution": ["EUR 706 500"], "Project_Title": ["Developing and implementation of a new generation of nanosafety assessment tools"], "Total_Cost": ["EUR 706 500"], "Country": ["Spain", "Italy", "United Kingdom", "Austria", "Greece", "Romania", "Cyprus", "Belgium"], "Project_ACR": ["NANOGENTOOLS"], "Technology_Description": "NanoMaterials safety is of great societal concern and raises many questions for the general public, governments, industry, scientists and regulators. Identifying and controlling the hazards associated with NMs is required to ensure the safety in parallel to exploiting the technological benefits.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other"], "From": ["2016-01-01"], "Project_ID": ["691095"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["ASTON UNIVERSITY"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Improving the economic feasibility of the biorefinery through catalysis engineering: enhancing the catalyst performance and optimizing valuable product yields"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ECOCAT"], "Technology_Description": "Catalytic pyrolysis of biomass is a process for the conversion of lignocellulosic biomass to a liquid product that has potential to be utilized as a fuel, a source of renewable chemicals and as an alternative to crude oil for upgrading to transportation fuels. ZSM-5 zeolite is the most studied catalyst for this process due to its acidity and shape-selectivity, which favour the conversion of biomass oxygenates to valuable aromatic hydrocarbons and limit the formation of coke. Among the shortcomings of the ZSM-5 zeolite is the small size of its pores; these small pores do not allow the large molecules in the pyrolysis vapours to access the active acid sites. Secondly, its sensitivity to biomass metals leads to poisoning and deterioration of its selectivity. Coupled with the high cost of the ZSM-5, the later leads to significant operating costs that arise from the necessity to replace the deactivated catalyst with fresh material at high rates.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["752941"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FUNDACIO CENTRE DE REGULACIO GENOMICA"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Mechanisms of selective transmission of epigenetic marks through the male germ line"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["EpiRetention"], "Technology_Description": "During spermatogenesis, germ cells go through important chromatin remodelling steps, the most striking being the replacement of histones by protamines, which promotes the compaction of the paternal genome in the sperm . However, a proportion of nucleosomes, ~1% in mice and ~15% in humans, are retained following protamine incorporation. It is thought that those remaining histones might play a role in the development process after fertilization possibly by transmitting epigenetic information to the progeny.", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-08-01"], "Project_ID": ["751651"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN", "THE UNIVERSITY OF NOTTINGHAM", "UNIVERSITAT POLITECNICA DE CATALUNYA", "LLOYD'S REGISTER EMEA IPS", "EQUIPOS NUCLEARES SA SME", "FULL SCALE DYNAMICS LIMITED", "PHI-MECA ENGINEERING", "THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN", "OVE ARUP & PARTNERS IRELAND"], "EU_Contribution": ["EUR 3 701 306,88"], "Project_Title": ["Training in Reducing Uncertainty in Structural Safety"], "Total_Cost": ["EUR 3 701 306,88"], "Country": ["Ireland", "United Kingdom", "Spain", "United Kingdom", "Spain", "United Kingdom", "France", "Ireland", "Ireland"], "Project_ACR": ["TRUSS"], "Technology_Description": "The growth of cities, impacts of climate change and the massive cost of providing new infrastructure provide the impetus for this proposal \u2013 entitled Training in Reducing Uncertainty in Structural Safety (TRUSS) \u2013 which will maximize the potential of infrastructure that already exists. If flaws in a structure can be identified early, the cost of repair will be vastly reduced, and here an effective monitoring system would allow identifying the optimum time to repair as well as improving structural safety. But safety is difficult to quantify and requires a deep understanding of the uncertainty associated to measurements and models for the structure and the loads. TRUSS will gather this understanding by bringing together an intersectoral and multidisciplinary collaboration between 4 Universities, 11 Industry participants and 1 research institute from 6 European countries. The consortium will combine and share expertise to offer training at an advanced level as new concepts for monitoring, modelling and reliability analysis of structures are emerging all the time. TRUSS will make knowledge of structural safety grow by incorporating these emerging technologies (hi-tech monitoring and manufacturing, computing, etc.) into the training programme and it will support job creation by enabling a wider talent pool of skilled and accredited engineering graduates with business, entrepreneurship, communication, project management and other transferrable skills. The training programme will be structured into taught modules combined with original research supported by secondments that will expose 14 fellows to both academia and industry. While developing tools that will reduce uncertainty in structural safety and improve infrastructure management, TRUSS will lay the basis for an advanced doctoral programme that will qualify graduates for dealing with the challenges of an aging European infrastructure stock, thereby enhancing their career prospects in both industry and academia.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["642453"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["UNIVERSITY OF EAST LONDON"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["(Re)Conceptualizing teacher educator professionalism"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ReconTEP"], "Technology_Description": "The need for a competent teaching force as a warrant for high quality education remains a central concern in many countries. Paradoxically, research focusing directly on the professional knowledge of teacher educators remains scarce. The implicit assumption is that a teacher educator simply teaches (his/her subject) in higher education and that teaching novice teachers does not require any additional preparation or expertise. As a result, a research-based understanding of teacher educators' professionalism is missing. This project addresses this knowledge gap and focuses on how teacher educators make sense of their work and enact their expertise. More specifically, we will study the content of teacher educators\u2019 professionalism by looking at how it actually operates in practice. Drawing on positioning theory, we frame teacher education practices as discursive practices in which teacher educators position both themselves and their student teachers in particular ways. These positionings strongly impact student teachers' (possibilities for) learning. Data collection includes videotaping of teacher education practices, biographical interviews (with teacher educators), questionnaires (with student teachers), and document analysis. This project will result in a systematic conceptualization of teacher educators' professionalism which is new to the field and offers a strong basis for future research. Results will also have direct knowledge utilization purposes for teacher educators themselves by opening powerful perspectives for them to understand possible threats to the effectiveness of their practice and actively work towards its improvement.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["751294"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FONDAZIONE PER L'ISTITUTO DI RICERC A IN BIOMEDICINA"], "EU_Contribution": ["EUR 265 840,20"], "Project_Title": ["Neutrophil subtypes: distinct cellular targets for therapeutic intervention"], "Total_Cost": ["EUR 265 840,20"], "Country": ["Switzerland"], "Project_ACR": ["TANTUMorNEUVACCINE"], "Technology_Description": "In cancer immunotherapy and vaccine field, considerable efforts have been invested to optimize the induction of effector T cells that, by recognizing tumor-specific or pathogen-associated antigens, control tumor cells or infections. ", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Switzerland"], "Activity": ["Research Organisations"], "From": ["2017-10-01"], "Project_ID": ["750973"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["MRI Signal To Recover Unique Cerebral TissUe Response to changEs"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["MRI-STRUCTURE"], "Technology_Description": "MRI-STRUCTURE is an innovative non-invasive imaging framework that will provide access to unexplored microstructural information in brain, targeting the scarcity of microstructural models able to extract meaningful biomarkers from the diffusion MRI signal in grey matter (GM). It is based on a synergy between different approaches: simulations, modeling, acquisition and analysis of real data, implementation of rodent model of brain insults, translation to human. The final aim of the project is to increase our knowledge of brain structure in health and disease, with a special focus on the themes of neuroinflammation, demyelination and axon degeneration. These physiological processes are interplaying phenomena involved in the brain\u2019s reaction to different stimuli, which have recently become a hot topic in brain research, due to their involvement in the pathogenesis of several neurodegenerative and psychiatric disorders. The specific objectives of MRI-STRUCTURE are: 1) to develop a new biophysical model of diffusion MRI in GM, capturing salient aspects of its microstructure; 2) to validate the model by triggering selective activation of different compartments in selected brain areas using established models of inflammation, demyelination and degeneration in rats; 3) to translate this approach to human brain in vivo in a cohort of healthy volunteers (during a secondment in CUBRIC, one of the European hubs for neuroimaging); and 4) to disseminate the framework to a wide clinical audience through a secondment in the startup Mint Labs, and explore its commercial applicability. An instrument with capacity to characterize relevant aspects of tissue microstructure in vivo and noninvasively is expected to have a tremendous impact on our knowledge of the pathophysiology of many brain pathologies, ultimately leading to early diagnosis, better (e.g., personalised) monitoring of the disease course and of the efficacy of new therapies.", "To": ["2019-01-15, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-01-16"], "Project_ID": ["749506"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Key Inorganics for Spintronics and MagnetoElectrics"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["KISS ME"], "Technology_Description": "Magneto-electric (ME) materials have been attracting considerable interest for their potential application in e.g. data-storage. Up to now, applications have been hindered by the weakness of the polarization generated by the ME effect. KISS-ME relies on the recent discovery by the host laboratory of inorganic compounds built on Low-Dimensional magnetic units. Dealing with 1D and 2D topologies carrying macrospins with large magnetization, they form the ideal playground for enhanced ME properties. The applicant proposes to quantify the ME performances on such phases and on new specifically-designed ones. This will allow to deduce the ideal chemical/structural/magnetic context for giant ME. It is a prerequisite for the prediction and synthesis of optimal multiferroics, limited so far by weak ME polarization and low temperature. Our multi-step strategy includes Design, Elaboration, Crystal Growth, Structural and Physical Characterization and theoretical modeling of relevant low-D ME.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["750971"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN"], "EU_Contribution": ["EUR 166 156,80"], "Project_Title": ["Antimatter gravity measurement: How does antihydrogen fall?"], "Total_Cost": ["EUR 166 156,80"], "Country": ["Austria"], "Project_ACR": ["ANGRAM"], "Technology_Description": "Antimatter research has become a crucial sphere in the continuous attempt to understand the Universe and its laws. The only stable, neutral antimatter atom available for laboratory study is the antihydrogen. We here propose to carry out a 30% measurement of the gravitational acceleration for antihydrogen, which will reveal the sign of gravity acting on antimatter, within the next two years. The principle is based on the rotation of a three grating moir\u00e9 deflectometer, coupled to a detector, and requires neither position resolution nor time-of-flight information for the through-going antihydrogen atoms. The realization of the measurement requires high quality simulations and the state-of-the art moir\u00e9 deflectometer, with gratings that are able to detect the annihilating antihydrogen atoms. The project goal will be reached through a series of software and hardware developments that are part of the implementation of the three work packages defined in the proposal. The main deliverables are new, faster simulations for antihydrogen annihilation and novel technologies for instrumentation for inertial sensing and detection of antimatter. In a more general context, this project proposal addresses the very fundamental question: do matter and antimatter fall in the same way? The Weak Equivalence Principle says that they must, but our understanding of antimatter is far from complete, with the baryon asymmetry in the Universe being one of the greatest unsolved problems in physics. A successful outcome of the proposed work will accelerate the researcher's growth towards her career goal: becoming a mature experimental physicist. At the same time, the host institution will greatly expand its influence in antimatter research and will benefit from new collaborators.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Austria"], "Activity": ["Research Organisations"], "From": ["2017-07-01"], "Project_ID": ["748826"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Short Videos to Increase Learners uptake on Online Content"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["c2LEARN"], "Technology_Description": "Introduction: Students use the Internet as the first point of contact when searching for learning materials to assist their studies. Such content may have a low evidence based background and may be misleading. One learning medium that is rated highly by students is the use of short educational videos. Objectives: The aim of this project is to create short video learning materials which are peer reviewed and accessible for dental students. Their creation and use will be an exemplar that may be used in dentistry and have a framework that allows translation into other disciplines. Material and Methods: A questionnaire will be distributed to European Dental Courses to verify their use of Information and Communication Technologies (ICT) with a focus on the use of short online videos. Following this short instructional videos will be created in several dental subjects and made available online following peer review. Their content will be evaluated qualitatively using face to face interviews with both students and their teachers. Following dissemination at dental education conferences, selected European partners will be invited to take part in evaluating the videos with a view to embedded them in their curriculum. The ER will learn new skills in qualitative research methodology and will develop a network of European Schools to evaluate new video production. Outcomes: This work will create a suite of dental videos that will be available to students across Europe. They will be peer reviewed and made available via the Internet to students. The project will develop a framework for future video creation by educators and will allow translation to other disciplines. The ER will learn a range of multidisciplinary skills including video creation, qualitative research methodology and have a suite of dental videos that will be made available to European Dental Schools. The host institution will benefit from how to embed ICT into dental education and with new partners.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["748609"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["MAGYAR TUDOMANYOS AKADEMIA AGRARTUDOMANYI KUTATOKOZPONT"], "EU_Contribution": ["EUR 146 239,20"], "Project_Title": ["Exploiting the legacy of Central European wheat landraces for improving the ecological adaptation ability of wheat"], "Total_Cost": ["EUR 146 239,20"], "Country": ["Hungary"], "Project_ACR": ["LANDRACES"], "Technology_Description": "Wheat the most important food crop in Europe with an increasing demand to preserve its production potential to ensure long-term food security. However, wheat is facing such challenges as climate change and the severe genetic bottleneck of cultivated wheat imposed by domestication, cannot surmount such difficulties. Wheat landraces are better adapted than modern cultivars to changing climate conditions and to stress environments. The conservation and effective management of crop diversity are thus essential to prepare future plant cultivars to the effects of climate change. A significant loss of named landrace varieties in both Europe and worldwide already caused a massive loss of crop genetic diversity and charged a substantial risk for future food security. The transfer of genetic diversity of European landraces into modern wheat cultivars can give valuable responses for climate change effects. The present study aims to introduce a high throughput state of the art genotyping system into the Hungarian breeding research to analyse the genetic diversity of the Central European landrace collection. The 15K wheat genotyping array uses 12.905 gene-based, predominantly haplotype-specific Single Nucleotide Polymorphism (SNP) markers providing a maximum of information accompanied by low analysis costs. We will use this genotyping system to identify favourable, new alleles of stress tolerance and quality in the Central European landraces. Comparisons to modern elite bread wheat cultivars will be presented and genome-wide association study will be carried out between SNPs and agronomically important traits. Phenotypic characterizations will be performed on 200 landraces and 70 modern wheat cultivars targeting ecological adaptation, biotic and abiotic stress tolerance and end-use quality. During this project we will identify new QTLs and genes, useful to improve limiting factors of grain yield, such as drought tolerance, plant phenology and resistance to diseases.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Hungary"], "Activity": ["Research Organisations"], "From": ["2017-10-01"], "Project_ID": ["752453"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM"], "EU_Contribution": ["EUR 172 800"], "Project_Title": ["Bottom-up PV module energy yield and integrated reliability model for site-specific design optimization"], "Total_Cost": ["EUR 172 800"], "Country": ["Belgium"], "Project_ACR": ["PVMINDS"], "Technology_Description": "Photovoltaic (PV) module reliability is a critical factor for energy yield predictability, and reduced PV cost of electricity. Today, there is limited understanding of PV reliability issues under real-field conditions; and none of the state-of-the-art energy yield models can predict their long-term performance considering lifecycle degradation and failure propagation. Ultimate objective of the planned research is to develop the first bottom-up reliability model for selected PV failure/degradation modes, coupled with advanced simulation of real-field stress factors. Broader vision of the Project is to yield a novel design-for-reliability (DfR) protocol for site-specific optimization of PV module concepts. Following a \u201cclosed-loop learning\u201d approach, the Project will be implemented in three workpackages (WP). In WP1, analysis of field diagnostic and meteorological data will be performed for selected PV installations and climatic zones, aiming to correlate degradation rates and/or failure occurrences, with site-specific stress factors. WP2 will involve the fabrication of PV samples; which, will undergo novel reliability tests based on insights from WP1, and enable the development of a novel physics/chemical PV reliability models that can be adapted to specific sites and module designs. Then, advanced simulations of PV lifecycle degradation, based on the reliability models coupled to bottom-up energy yield modelling will be developed in WP3. Final results of the project will be a predictive reliability tool and site-specific PV design and qualification guidelines. The project brings together the know-how of the Host, in advanced energy yield modelling and PV module technology innovation and characterization, and the applicant\u2019s experience in PV field diagnostics and reliability; thus, giving a multidisciplinary training by research to the applicant in industrial research environment at an independent research center.", "To": ["2020-02-18, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Belgium"], "Activity": ["Research Organisations"], "From": ["2018-02-19"], "Project_ID": ["752117"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FONDAZIONE ENI ENRICO MATTEI"], "EU_Contribution": ["EUR 168 277,20"], "Project_Title": ["Infrastructural path dependence and irreversible investment in the integrated assessment of energy and climate policies"], "Total_Cost": ["EUR 168 277,20"], "Country": ["Italy"], "Project_ACR": ["INFRACLIMATE"], "Technology_Description": "The objective of this project is to analyse the role of path dependence due to infrastructural lock-in and irreversible investment decisions for the design of optimal energy and climate policies. The project brings together several strands of economics research, namely macroeconomics, public economics, environmental and resource economics and risk and uncertainty, with climate change and energy economics into an integrated assessment. INFRACLIMATE is aimed to go beyond standard models designed to study energy and climate policies, by incorporating irreversible investment decisions, inertia in energy systems and possibility of underutilization of capital stocks. The project has three main objectives. Firstly, to carry out innovative research in the theoretical understanding of the interplay between irreversible investment decisions, high persistence in capital stocks and climate policies. Second, extending the existing Green Paradox literature by focusing on how the irreversibility of investment decisions affect the supply of fossil fuels, and thirdly, to develop a fully-fledged integrated assessment model of economy, energy and climate to quantify the effects of climate policies on investment decisions and the amount of stranded capital assets. A key ingredient of the analysis will be how various forms of uncertainty affect the interactions between investment decisions and climate policies. In doing so, the project will be able to provide a richer characterization of investment decisions and their interaction with energy and climate policies, and to quantify welfare effects of different policy options. INFRACLIMATE is a timely and highly policy relevant project given Europe\u2019s pledges to emissions reductions, high infrastructural lock-ins in the extraction and power sector, and uncertainties about future technological innovations and government\u2019s environmental policies.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["747405"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FUNDACIO CENTRE DE REGULACIO GENOMICA"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Reprogramming of elite B cells to induced hematopoietic stem cell with microRNAs and transcription factors"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["miRStem"], "Technology_Description": "Generating Hematopoietic Stem Cells (HSCs) by Transcription Factor (TF) overexpression is of great interest in the stem cell field and promises considerable therapeutic potential. Among the systems described so far only one study, using murine B cells, has led to the generation of transplantable induced HSCs (iHSCs), although at exceedingly low efficiencies and using combinations between 6 and 8 TFs. We propose here a new approach to generate iHSCs based on the use of newly identified highly plastic \u201celite\u201d type cells for reprogramming by the Yamanaka factors into induced pluripotent stem cells, generated by the transient exposure of B cells to C/EBP\u03b1. Hypothesizing that microRNAs could potentiate the effect of TFs in HSC reprogramming we will also analyze the effects of microRNA overexpression. For this we will first analyze HSCs and different hematopoietic progenitors to identify differentially expressed microRNAs. Different combinations of selected microRNAs will be cloned into inducible retroviral vectors together with hematopoietic TFs and used to infect \u201celite\u201d CEBP\u03b1-primed B cells to screen for the induction, in vitro and in vivo, of iHSCs. The use of colony assays, cell surface marker and transcriptomic analyses of the resulting cells, as well as transplantation into irradiated mice, will enable us to identify microRNAs and TFs combinations that induce HSC reprogramming. The heterogeneity of iHSCs will then be tested by single cell expression analysis using RNA-seq. This project will provide new insights into the reprogramming of HSCs, the clinically most important type of adult stem cells, with potential medical applications. The proposed action will benefit the applicant\u2019s career through acquisition of scientific maturity and independence.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["747539"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["COPENHAGEN BUSINESS SCHOOL"], "EU_Contribution": ["EUR 200 194,80"], "Project_Title": ["Cross-Cultural Experimental Analyses of Tax Morale"], "Total_Cost": ["EUR 200 194,80"], "Country": ["Denmark"], "Project_ACR": ["ChEATAX"], "Technology_Description": "Tax evasion is a large and growing problem in almost all countries (Murphy\u2019s 2012 report \u201cClosing the European Tax Gap\u201d estimated that \u201ctax evasion in the European Union is approximatively \u20ac 860 billion a year\u201d). This problem is particularly extreme in Southern European countries as Italy, Spain and Greece. Recent experimental and survey analyses revealed that individual\u2019s intrinsic motivation to pay taxes is not only influenced by tax rates and audit probabilities, but also by social and cultural norms. Designing effective policies for reducing tax evasion thus requires understanding the behavioural aspects of tax compliance decisions. The previous experimental analyses on tax compliance were mainly carried out in the Centre-North of Italy (Milan, Bologna and Rome) and assumed the taxpayer as an isolated individual. My proposed research, entitled \u201cCross-Cultural Experimental Analyses of Tax Compliance\u201d (ChEATAX) will innovate by taking a broader perspective on tax morale from the perspectives of both geography and level of analysis. In this way, ChEATAX can advance knowledge by addressing two long-standing gaps in the literature: the North-South discrepancies in Italian tax compliance, and the impact of social norms and social interactions on tax morale. To isolate cultural effects as a factor in tax compliance, this aim will be pursued by collecting survey and laboratory data in Italy and Denmark, respectively representing Southern and Northern European societies, and in the South and the North of Italy to capture disparities in Italian tax compliance. The outputs of this project will help understanding how different countries can establish and foster cooperation with taxpayers to enforce tax compliance.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["748062"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich"], "EU_Contribution": ["EUR 175 419,60"], "Project_Title": ["Colour and Kinematics of Quarks and Gluons inside Loops"], "Total_Cost": ["EUR 175 419,60"], "Country": ["Switzerland"], "Project_ACR": ["InsideLoops"], "Technology_Description": "The LHC era of fundamental physics presents a formidable challenge for theorists - the precision of Standard Model predictions should be improved by a factor of two. One of the major bottlenecks is the availability of two-loop scattering amplitudes in quantum chromodynamics (QCD), which is largely limited to 2 -> 2 processes due to the daunting complexity of the perturbative series. The need for amplitudes of higher-multiplicity processes calls for new analytic insights into the intricate structure of gauge theories.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["746138"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["Co-Translational Chaperone Action at the Single-Molecule Level"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["COTCA"], "Technology_Description": "The mechanism of protein translation by ribosomes has been the focus of recent single molecule investigations. Understanding translation at a single-molecule level is of particular interest to the life sciences and relevant for various degenerative diseases. Although protein translation and folding are well studied subjects, cotranslational folding has been proven difficult to observe. How proteins adopt their native structure with efficient fidelity while being synthesized by the ribosome remains largely unexplored. Using optical tweezers we recently measured the mechanics of synthesis and simultaneous folding in real-time, in the absence of chaperones. We found that cotranslational folding occurs at predictable sequence locations, exerting forces on the nascent polypeptide chain. We showed that transient pauses of translation occur in particular locations along the protein sequence, facilitating native secondary structure formation. Several crucial mechanistic questions concerning the effects of chaperones on co-translational folding remain unanswered: How do the chaperones trigger factor (TF), the major bacterial heat shock protein 70 (Hsp70/DnaK) and the GroEL/ES chaperonin system affect cotranslational protein folding? Do they affect the translation rate? What effect do the chaperones have on initial hydrophobic collapse? When and how often do they (un)bind? How do these chaperones assure reliable and fast native folding during protein synthesis? Here, I propose a combined optical tweezers and laser scanning confocal microscopy study to investigate the effects of chaperones on cotranslational folding in real-time, using the host's instruments, chaperones and collaboration network, as well as my previously developed cotranslational assay and collaboration network. The group of Prof. S. J. Tans at AMOLF with its expertise and experience in single-molecule chaperone investigations is ideally suited for me to pursue this study of cotranslational chaperone activity.", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Research Organisations"], "From": ["2017-08-01"], "Project_ID": ["745798"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["RNA localization in bacteria"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["NucLoc"], "Technology_Description": "In eukaryotic cells mRNAs can be localized to specific places within a cell to achieve protein synthesis with spatiotemporal control. Recently, I and others have shown that prokaryotes can also target mRNAs to specific parts of the cell. However, these studies have been restricted to a limited number of mRNAs and were performed with Gram-negative bacteria, and due to the serendipitous nature of these discoveries and conflicting results, it is not clear how widespread mRNA localization is in a bacterial cell and what conserved mechanisms are playing a role. To investigate this, I will first employ a novel CLIP-seq-inspired deep-sequencing-based approach to gain an unbiased view of mRNAs enriched at the cell periphery and cell poles of the Gram-positive model bacterium Bacillus subtilis. This dataset will reveal the scope of mRNA targeting by the Signal Recognition Particle (SRP) and will reveal mRNAs that use another mechanism for cellular targeting. In addition, classic CLIP-seq experiments will be used to identify mRNAs that use the cytoskeleton and other morphological proteins for targeting. As a complementary approach, I will assess the localization of mRNAs coding for different classes of localized proteins (polar, cell division, cytoskeletal, membrane, secreted, motility, nucleoid and chaperone proteins) using the established fluorescence in situ hybridization (FISH) technique. Information obtained from these experiments will subsequently be used to investigate the role of protein translation, RNA sequences, genome location and cell morphology in mRNA localization, to gain functional insight into the mechanisms responsible for this basic morphogenetic process.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["749510"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["VILNIAUS GEDIMINO TECHNIKOS UNIVERSITETAS VIESOJI ISTAIGA"], "EU_Contribution": ["EUR 130 779,60"], "Project_Title": ["Sustainable Fibre-Reinforced Polymer Concrete (FRP-RC) Structures"], "Total_Cost": ["EUR 130 779,60"], "Country": ["Lithuania"], "Project_ACR": ["SusFRPRC"], "Technology_Description": "The corrosion problem of steel reinforcement severely limits the life-cycle sustainability of conventional reinforced concrete structures. This proposal focuses on the use of corrosion-free fibre-reinforced polymer (FRP) reinforcing bars in lieu of steel reinforcing bars in concrete structures. Due to the currently incomplete understanding of serviceability aspects of FRP reinforced concrete (FRP-RC) structures, the existing design guidelines are not comprehensive, and this restricts the applications of FRP-RC in real-life. The proposed project will investigate the fundamental issues of serviceability, fracture mechanics and time-dependent effects of FRP-RC to enable its practical usage. The objectives encompass experimental investigation of deformation characteristics of FRP-RC specimens, derivation of constitutive models and establishment of deformation capacity of FRP-RC members, formulation of design guidelines in serviceability and development of design aids for use by practising engineers.", "To": ["2019-04-05, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Lithuania"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-06"], "Project_ID": ["751461"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAET ULM"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Cold Molecules in Cavities"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["CoMiC"], "Technology_Description": "Here we propose a radically new way to control chemical reactions on the quantum level. The Experienced Researcher (ER) will combine his long-standing expertise on cavity quantum electrodynamics (CQED) with the field of ultracold chemical reactions, in which the host is one of the leading pioneers. We want to drive a photo-chemical reaction (photoassociation) within an optical cavity and in this way gain control over the reaction (objective 1). For this, we use the control over spontaneous photon emission by an optical cavity, as has been done with single atoms. This paves the way towards novel fascinating effects like superradiant chemistry, where a chemical process is enhanced due to quantum statistics. Furthermore, the optical cavity will be used as an ultrasensitive molecule detector of a new quality by detecting them without disturbing their quantum state (objective 2). This novel interdisciplinary combination of physics and chemistry will open up a new research field, where the ER will demonstrate scientific innovation and independence.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["747160"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["Microscopic Probes of Inflationary Cosmology"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["INFPROBES"], "Technology_Description": "The theory of cosmic inflation is the current paradigm for early universe cosmology. I propose a research and training programme centered around two themes in inflationary cosmology. First, I will determine new signatures of high-energy physics in inflation i) by finding new shapes of non-Gaussianity, in particular signatures from the tower of higher-spin states predicted in high-energy completions of gravity such as string theory, and also ii) by studying natural extensions of the tensor sector, in particular higher spin fields with partial gauge symmetries, and the imprints left by these fields in tensor non-Gaussianity and in the cosmic microwave background (CMB) radiation. To achieve i) and ii), I will use methods of field theory in curved backgrounds, as well as general symmetry properties of cosmological correlation functions. Second, I will study quantum instabilities in de Sitter space, as well as an analogue in flat space, a constant background electric field. The instabilities will be determined by studying response functions and vacuum polarization in strong fields. The signatures proposed in the first theme will provide tools to perform particle spectroscopy and determine the field content of inflation. The effects proposed in the second theme are a potential microscopic mechanism for the dynamics of inflation. ", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["751778"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Three-Dimensional Perovskite Oxides as Working ElectRochemical devices"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["3D-POWER"], "Technology_Description": "Three-Dimensional Perovskite Oxides as Working ElectRochemical devices (3D-POWER) will focus on utilization of perovskite oxides in combination with functional metallic materials to address the specific demands of sustainable energy sector. The so formed 3D structures will serve as promising electrodes for the development of electrochemical devices such as solid oxide fuel cells, electrolyzers, batteries and supercapacitors. Specifically, within this project atomically layered perovskites including La1-xSrxCo1-yFeyO3 (LSCF) and La1-xSrxMnO3 (LSM) will be synthesized through pulsed laser deposition and/or molecular beam epitaxy on pre-designed 3D substrates of Copper or Iron depending on growth conditions of perovskites and eventual applications of the electrodes. These substrates will be uniquely fabricated by nanoscribe printing of metals to cast a 3D scaffold like support for the growth of perovskites and later will be chemically etched off. Further, the performance of these perovskite constructs will be enhanced by depositing highly functional transition metal dichalcogenides (TMDs). This will serve as interconnects due to their excellent electrical, chemical and physical properties and overall enhance device\u2019s catalytic activity.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["751531"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FONDAZIONE ENI ENRICO MATTEI"], "EU_Contribution": ["EUR 180 277,20"], "Project_Title": ["Mining, lobbying and efficient environmental policy"], "Total_Cost": ["EUR 180 277,20"], "Country": ["Italy"], "Project_ACR": ["MILO"], "Technology_Description": "Natural resources including raw materials are important for the European Union since they are a part of the base of the economy and simultaneously a large pollution and waste source. Sustainable development of the mining sector extracting the raw materials calls for an economic analysis of environmental policy, which is the central theme of the MILO-project. The objective of the project is to investigate the optimal environmental policy of the mining sector with a special emphasis on mining specific features and the choice of policy instruments under lobbying. Through its research results obtained using dynamic optimization methods, game theory and an array of dissemination and communication efforts, the project will help to improve the currently applied policies in Europe. In addition to policy advice, the project will result in new insights on the formation of lobby groups and policy instruments by combining two game theoretical approaches, namely, the common agency framework and coalition theory modeling. The researcher, who is trained in the theory of environmental policy instruments and dynamic optimization methods, will conduct the research and training in FEEM\u2019s international and interdisciplinary working environment and will be supervised by an expert in the research field. The project with its trainings improves his research and transferable skills, and extends his international networks through the host\u2019s contacts and through a research visit. By including versatile training-through-research, multiple dissemination and communication methods, public engagement through the MILO-webpage and blog, and networking the project has a strong impact on the researcher\u2019s career, on the future research collaboration as well as on the public interest.", "To": ["2019-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations"], "From": ["2017-12-01"], "Project_ID": ["748066"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERZA V LJUBLJANI"], "EU_Contribution": ["EUR 157 287,60"], "Project_Title": ["Demonstration and implementation of an integrated process for the Plasma-Enhanced Chemical Solution Deposition of PMMA-multicomponent coatings on wood and wood-based substrates"], "Total_Cost": ["EUR 157 287,60"], "Country": ["Slovenia"], "Project_ACR": ["PlasmaSolution"], "Technology_Description": "This action will implement the new Plasma-Enhanced Chemical Solution Deposition (PECSD) technique for coating of wood and wood-based substrates. This technique synergistically employs plasma-chemistry in the gas phase and polymer chemistry in the liquid formulation, thus combining all benefits of conventional surface coatings and plasma-based deposition technologies. This will be carried out as a novel integrated process for the continuous coating of substrates including three steps:", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Slovenia"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["745936"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF LIVERPOOL"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Parametrised Verification and Control"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["PaVeCo"], "Technology_Description": "A variety of interesting systems -- servers that fail with a certain probability; biological models, where proteins are produced with a given rate; automotive and aeronautical systems -- displays stochastic behaviour. As a fully automated method to analyse such systems, stochastic model checking is an important research area.", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["753351"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Voltage-sensing nanorods for super-resolution voltage imaging in neurons"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["NanoVoltSens"], "Technology_Description": "In the last decade, the rapidly developing optical imaging field has significantly improved our understanding of information processing in the brain. Although a number of promising tools have been designed, sensors of membrane potential are lagging behind. In this project we aim to characterize an innovative voltage sensor for neurons that is fundamentally different from the existing ones. Our sensor is based on targetable voltage-sensing semi-conductor nanorods (vsNRs) that self-insert into the neuronal membrane. The rods optically and non-invasively record action potentials at the single particle level, at multiple sites, and across a large field-of-view. Such vsNRs offer unique advantages, including: (1) large voltage sensitivity, (2) ratiometric imaging based on a large spectral shift as function of voltage, (3) very fast response times in the range of ns, (4) very high brightness that affords single-particle detection, and (5) excellent performance in the near-infrared spectral range. ", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2017-05-01"], "Project_ID": ["752019"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF SHEFFIELD", "CONSIGLIO NAZIONALE DELLE RICERCHE", "GOETEBORGS UNIVERSITET", "UNIVERSIDAD DE EXTREMADURA", "CITY OF BRADFORD METROPOLITAN DISTRICT COUNCIL", "STOCKHOLMS STAD", "SHEFFIELD CITY COUNCIL", "SOFTECO SISMAT SRL", "SHAPING CLOUD LTD"], "EU_Contribution": ["EUR 283 500"], "Project_Title": ["Promoting Sustainable Freight Transport in Urban Contexts:Policy and Decision-Making Approaches"], "Total_Cost": ["EUR 283 500"], "Country": ["United Kingdom", "Italy", "Sweden", "Spain", "United Kingdom", "Sweden", "United Kingdom", "Italy", "United Kingdom"], "Project_ACR": ["PROSFET"], "Technology_Description": "Within a context of growing urban population, advances in urban logistics operations and improved local authority planning, especially in the field of the urban freight transport, can alleviate the associated negative environmental and economic impacts occurring in cities.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["734909"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["DUBLIN CITY UNIVERSITY", "UNIVERSITY COLLEGE LONDON", "UNBABEL, LDA", "THE COCHRANE COLLABORATION"], "EU_Contribution": ["EUR 229 500"], "Project_Title": ["The INTERnAtional network on Crisis Translation"], "Total_Cost": ["EUR 279 000"], "Country": ["Ireland", "United Kingdom", "Portugal", "United Kingdom"], "Project_ACR": ["INTERACT"], "Technology_Description": "We propose to establish an interdisciplinary, intersectoral and international research and innovation network in Crisis Translation, called INTERACT. Crisis Translation is understood here as the translation of written information from one linguistic and cultural system to another in the context of a crisis scenario, with a view to enabling affected communities and responders to be prepared for crises, improve resilience and reduce the loss of lives. Due to the transboundary nature of modern day crises, crisis communication must be multilingual and multilingual crisis communication is enabled through translation. Multilingual information access through translation addresses work programme aims such as social fairness and democratic access to essential information for all. The primary focus of INTERACT is on health-related crisis content. The main objectives of the project are 1) to make meaningful and effective contributions to knowledge, policies, expertise, training and technology that enable accurate and timely translation-enabled crisis communication, with a particular focus on health-related content; 2) to improve outcomes for crisis-affected and at-risk communities by contributing to translation-enabled communication to, with and from those communities; 3) to enhance human skills, competences and cross-sectoral collaboration across academic, humanitarian, and industrial sectors involved in crisis translation. This will be achieved by focusing on five main topics: crisis communication policy, comprehension in limited proficiency communities, crisis machine translation, citizen translator education, and ethics and through collaboration across academic, SME, NGO, and Multinational partners. The contribution of INTERACT will be a much broader, better informed, innovative, much more impactful perspective on the challenges of crisis communication and the role of translation.", "To": ["2020-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other"], "From": ["2017-04-01"], "Project_ID": ["734211"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["BAUHAUS-UNIVERSITAET WEIMAR", "CISM-LAB SRL", "inuTech GmbH", "TECHNISCHE UNIVERSITEIT EINDHOVEN", "GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER", "UNIVERSITY OF DURHAM"], "EU_Contribution": ["EUR 1 669 500"], "Project_Title": ["Environmentally best practices and optmisation in hydraulic fracturing for shale gas/oil development"], "Total_Cost": ["EUR 1 930 500"], "Country": ["Germany", "Italy", "Germany", "Netherlands", "Germany", "United Kingdom"], "Project_ACR": ["BESTOFRAC"], "Technology_Description": "This research brings together the complementary expertise of our consortium members to gain a better understanding of the physics in hydraulic fracturing (HF) with the final goal to optimize HF practices and to assess the environmental risks related to HF. This requires the development and implementation of reliable models for HF, scaled laboratory tests and available on-site data to validate these models. The key expertise in our consortium is on modelling and simulation of HF and all partners involved pursue different computational approaches. However, we have also some partners in our consortium which focus on scaled laboratory tests and one company which can provide on-site data. The choice of the best model for HF still remains an open question and this research promises to quantify uncertainties in each model and finally provide a guideline how to choose the best model with respect to a specific output parameter. The final objective is to employ these models in order to answer some pressing questions related to environmental risks of HF practices, including ", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["734370"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["POTSDAM INSTITUT FUER KLIMAFOLGENFORSCHUNG"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Integrating climate impact and spatial microsimulation modelling for improved climate change adaptation decision-making"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["CLIMOD"], "Technology_Description": "Minimising the welfare cost of climate change requires effective adaptation policies. Consequently, the EU strategy on climate change adaptation prioritises the creation of \u2018frameworks, models and tools to support decision-making and to assess [the effectiveness of] various adaptation measures\u2019. Accurate measurement of welfare cost is a prerequisite for effective policy prioritisation. The current state of the art quantifies welfare costs using aggregated methodologies. This has been shown to bias cost estimation and does not capture the socioeconomic distribution of welfare impacts. This bias may therefore affect the effectiveness of adaptation measures. Integrating climate impact models (with which Prof Lotze-Campen and the Potsdam Institute for Climate Impact Research [PIK] are experts) with Spatial Microsimulation (SM) modelling (with which the experienced researcher, Dr. Farrell, is an expert) provides a framework to estimate micro-level welfare impacts and thus overcome these deficiencies. Furthermore, this project integrates these estimates into decision-making models to aid policy. ", "To": ["2020-04-01, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations"], "From": ["2018-04-02"], "Project_ID": ["743582"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE DE LAUSANNE", "UNIVERSITE DE LAUSANNE"], "EU_Contribution": ["EUR 2 499 969"], "Project_Title": ["Resilience in ant societies"], "Total_Cost": ["EUR 2 499 969"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["resiliANT"], "Technology_Description": "Complex systems are found at all levels of biological organisation, from molecules to ecosystems. Despite the huge differences in scale, each of them has evolved homeostatic processes conferring resilience to external perturbations. Ants provide an ideal system to identify behavioural responses allowing biological systems to recover from disturbance. The overall aim of this proposal is to identify the collective mechanisms responsible for this resilience. This will be achieved by conducting both abiotic and biotic perturbations. Abiotic perturbations such as flooding frequently have major effects on the demography of the workforce, for example by whipping out all the foragers. We will therefore perform highly controlled perturbations (e.g., targeted removal of worker groups) designed to induce compensatory changes in the behavioural trajectories of the remaining ants to test whether ants can deviate from their baseline behavioural trajectory to mitigate the effect of external perturbations A major biotic challenge faced by all highly social species is the rapid spread of disease between closely-packed conspecifics. Because the kinetics of disease transmission in social groups depends upon the structure of the interaction network, we will investigate how the prophylactic properties of the social interaction network emerge from the individual-level behaviours. Finally, we will perform controlled inoculations with a generalist fungal pathogen to identify active individual-level behavioural responses that further hinder pathogen transmission. The proposed studies which capitalise on two recent methodological advancements (the development of sophisticated network analysis tools and, a tracking system which allows unprecedented collection of behavioural data (e.g., millions of pairwise interactions) will make important contributions to our understanding of processes involved in resilience of complex systems and how animal societies respond to stochastic environments.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["741491"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN", "LULEA TEKNISKA UNIVERSITET", "OUTOTEC OYJ"], "EU_Contribution": ["EUR 1 596 958,56"], "Project_Title": ["European Industrial Doctorate in future efficient minerals analysis, processing and training"], "Total_Cost": ["EUR 1 596 958,56"], "Country": ["Ireland", "Sweden", "Finland"], "Project_ACR": ["MetalIntelligence"], "Technology_Description": "MetalIntelligence proposes an EID in future efficient minerals analysis, processing and training. Transformational change caused by the third industrial revolution, which itself relies on extraction of raw materials, provides the impetus. A resource-efficient EU is recognised as a societal challenge. However, the pathway from searching for mineral deposits to metal production is complex and involves a number of sectors (geosciences, chemical analysts, mining, processing, metallurgy) that have tended to work in silos. Limited intersectoral collaboration has led to compartmentalised thinking which has become an impediment to improved resource and energy efficiency.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-09-01"], "Project_ID": ["722677"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 1 999 775"], "Project_Title": ["Abstraction and Generalisation in Human Decision-Making"], "Total_Cost": ["EUR 1 999 775"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["NEUROABSTRACTION"], "Technology_Description": "Intelligent agents make good decisions in novel environments. Understanding how humans deal with novelty is a key problem in the cognitive and neural sciences, and building artificial agents that behave effectively with novel settings remains an unsolved challenge in machine learning. According to one view, humans form abstract representations that encode latent variables pertaining to the high-level structure of the environment (a \u201cmodel\u201d of the world). These abstractions facilitate generalisation of extant task and category information to novel domains. For example, an individual who can ride a bicycle, or speak Spanish, will learn more rapidly to ride a motorcycle, or speak Portuguese. However, the neural basis for these abstractions, and the computational underpinnings of high-level generalisation, remain largely unexplored topics in cognitive neuroscience. In the current proposal, we describe 4 experimental series in which humans learn to perform structured decision-making tasks, and then generalise this behaviour to input domains populated by previously unseen stimuli, categories, or tasks. Building on extant pilot work, we will use representational similarity analysis (RSA) of neuroimaging (fMRI or EEG) data to chart the emergence of neural representations encoding abstract structure in patterns of brain activity. We will then assess how the formation of these abstractions at the neural level predicts successful human generalisation to previously unseen contexts. Our proposal is centered around a new theory, that task generalisation depends on the formation of low-dimensional population codes in the human dorsal stream, that are scaffolded by existing neural basis functions for space, value and number. The work will have important implications for psychologists and neuroscientists interested in decision-making and executive function, and for machine learning researchers seeking to build intelligent artificial agents.", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["725937"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITA COMMERCIALE LUIGI BOCCONI", "UNIVERSITA COMMERCIALE LUIGI BOCCONI"], "EU_Contribution": ["EUR 1 499 375"], "Project_Title": ["Social Mobility and Inequality across Italy and Europe: 1300-1800"], "Total_Cost": ["EUR 1 499 375"], "Country": ["Italy", "Italy"], "Project_ACR": ["SMITE"], "Technology_Description": "The goal of SMITE is to improve our knowledge of long-term trends in social mobility, from the decades immediately preceding the Black Death of 1347-49 up until the eve of Industrialization. The objective is not only to measure mobility, but also to understand its consequences for the economy and society at large. Very few data about preindustrial social mobility are available today, especially for southern Europe. SMITE will collect an extensive database about social mobility, measured in different ways including: economic mobility across wealth classes and occupational mobility. Archival research will be concentrated on Italy where excellent sources exist, but the Italian case will be placed in the wider European context. The few existing databases from all over the continent will be collected for comparison and direct research will be done on some regions of Europe beyond Italy, especially in France, Spain and the Low Countries.", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["725687"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS", "THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS"], "EU_Contribution": ["EUR 2 161 502"], "Project_Title": ["Civil Law, Common Law, Customary Law: Consonance, Divergence and Transformation in Western Europe from the late eleventh to the thirteenth centuries"], "Total_Cost": ["EUR 2 161 502"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["CLCLCL"], "Technology_Description": "A highly significant division in present-day Europe is between two types of legal system: the Continental with foundations in Civil Law (law with an ultimately Roman law basis), and English Common Law. Both trace their continuous history back to the twelfth century. The present project re-evaluates this vital period in legal history, by comparing not just English Common Law and Continental Civil Law (or \u201cIus commune\u201d), but also the customary laws crucially important in Continental Europe even beyond the twelfth century. Such laws shared many features with English law, and the comparison thus disrupts the simplistic English:Continental distinction. The project first analyses the form, functioning and development of local, national, and supra-national laws. Similarities, differences, and influences will then be examined from perspectives of longer-term European legal development. Proper historical re-examination of the subject is very timely because of current invocation of supposed legal histories, be it Eurosceptic celebration of English Common Law or rhetorical use of Ius commune as precedent for a common European Law.", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-ADG - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["740611"], "Call_for_Proposal": ["ERC-2016-ADG"]}, -{"Partners": ["UNIVERSITY OF GLASGOW", "UNIVERSITY OF GLASGOW"], "EU_Contribution": ["EUR 149 995"], "Project_Title": ["Acoustics for Next Generation Sequencing"], "Total_Cost": ["EUR 149 995"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["ACOUSEQ"], "Technology_Description": "Since completion of the first human genome sequence, the demand for cheaper and faster sequencing methods has increased enormously. This need has driven the development of second-generation sequencing methods, or next-generation sequencing (also known as NGS or high throughput sequencing). The creation of these platforms has made sequencing accessible to more laboratories, rapidly increasing the volume of research, including clinical diagnostics and its use in directing treatment (precision medicine). The applications of NGS are also allowing rapid advances in clinically related fields such as public health and epidemiology. Such developments illustrate why sequencing is now the fastest-growing area in genomics (+23% p.a.). The activity is said to be worth $2.5B this year, and poised to reach ~$9B by 2020. In any workflow, prior to the sequencing reactions, a number of pre-sequencing steps are required, including the fragmentation of the DNA into smaller sizes for processing, size selection, library preparation and target enrichment. This proposal is specifically concerned with this latter area, namely DNA fragmentation \u2013 now widely acknowledged across the industry as being the most important technological bottleneck in the pre-sequencing workflow. Our new method for DNA fragmentation \u2013 involving using surface acoustic waves will enable sample preparation from lower sample volumes using lower powers. It also has the potential to allow the seamless integration of fragmentation into sequencing instrumentation, opening up the possibility of \u201csample to answer\u201d diagnostics. In the near term this will enable the implementation of sample preparation pre-sequencing steps within the NGS instruments. In the longer term, our techniques will also enable us to develop methods for field-based DNA sequencing \u2013 as may be required for determining \u201cmicrobial resistance\u201d and informing the treatment of infectious disease in the face of the emergence of drug resistance.", "To": ["2018-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["737557"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN", "THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Memory Engram Maintenance and Expression"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Ireland", "Ireland"], "Project_ACR": ["MEME"], "Technology_Description": "The goal of this project is to understand how specific memory engrams are physically stored in the brain. Connectionist theories of memory storage have guided research into the neuroscience of memory for over a half century, but have received little direct proof due to experimental limitations. The major confound that has limited direct testing of such theories has been an inability to identify the cells and circuits that store specific memories. Memory engram technology, which allows the tagging and in vivo manipulation of specific engram cells, has recently allowed us to overcome this empirical limitation and has revolutionised the way memory can be studied in rodent models. Based on our research it is now known that sparse populations of hippocampal neurons that were active during a defined learning experience are both sufficient and necessary for retrieval of specific contextual memories. More recently we have established that hippocampal engram cells preferentially synapse directly onto postsynaptic engram cells. This \u201cengram cell connectivity\u201d could provide the neurobiological substrate for the storage of multimodal memories through a distributed engram circuit. However it is currently unknown whether engram cell connectivity itself is important for memory function. The proposed integrative neuroscience project will employ inter-disciplinary methods to directly probe the importance of engram cell connectivity for memory retrieval, storage, and encoding. The outcomes will directly inform a novel and comprehensive neurobiological model of memory engram storage.", "To": ["2022-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-02-01"], "Project_ID": ["715968"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE"], "EU_Contribution": ["EUR 1 999 999"], "Project_Title": ["A Wearable Electronics Approach To Reduce Mortality in Epilepsy"], "Total_Cost": ["EUR 1 999 999"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["NOSUDEP"], "Technology_Description": "Epilepsy is a neurological condition that affects approximately 1% of the population (or over 50 million people in the world). Europe alone is home to 6 million people that suffer from epilepsy with one new case every minute. In certain cases, healthy patients with epilepsy can die suddenly and unexpectedly. This is known as Sudden Unexpected Death in Epilepsy (SUDEP). SUDEP kills thousands of people in Europe every year. Unfortunately the mechanisms of SUDEP are not known, which makes it unpredictable Individuals with refractory tonic-clonic or complex-partial seizures are at the highest risk of SUDEP. These comprise approximately one third of the population affected by epilepsy, i.e. in the order of 2 million people in Europe.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["724334"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN", "THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN"], "EU_Contribution": ["EUR 129 773,75"], "Project_Title": ["2D nanomaterials-based composite films for more efficient thermal conduction"], "Total_Cost": ["EUR 129 773,75"], "Country": ["Ireland", "Ireland"], "Project_ACR": ["TC2D"], "Technology_Description": "The aim of this proposal is to determine the economic and technical feasibility of using readily scalable technologies for the development of inexpensive and high performance solutions for heat dissipation for the high-end automobile industry, as well as other markets including household appliances, injection moulding, advanced aircraft and pharmaceutical manufacturing, ranging from the actual fabrication protocols, down to a wide range of finite products. ", "To": ["2018-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-12-01"], "Project_ID": ["727420"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["TECHNISCHE UNIVERSITAET MUENCHEN", "TECHNISCHE UNIVERSITAET MUENCHEN"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Constructing and powering nanoscale DNA origami motors"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["DNA ORIGAMI MOTORS"], "Technology_Description": "Our goal is to advance the field of DNA nanotechnology by achieving directed transport on the nanoscale using robustly functioning synthetic motor units. To do so, we propose to construct spatially periodic, diffusive mechanisms that have broken inversion symmetry and to subject these mechanisms to conditions away from thermal equilibrium. We will build on recent progress in creating complex DNA-based structures and construct various nanoscale rotary and translational Brownian ratchet mechanisms that have well- defined degrees of freedom for motion within periodic and asymmetric energy landscapes. The mechanisms will be self-assembled from DNA origami components. We will use cryo-Transmission Electron Microscopy (TEM) to evaluate and iteratively refine our structures. Conventional video-rate fluorescence microscopy, in addition to super-resolution microscopy, will be employed to study in solution and in real time the diffusive motion of the mechanisms on the single particle level. We will introduce various deterministic or stochastic thermal, mechanical, or chemical perturbations to drive the systems away from thermal equilibrium. We will use laser heating and cooling to experimentally test thermal and flashing ratcheting mechanisms; we will employ dissipative asymmetric fluxes arising in active matter as realized in high-density ATP-hydrolysing motility assays; and we will couple out-of-equilibrium chemical reactions to the motion of our mechanisms. The ultimate goal of our work is to take insights from these experiments and create robustly functioning nanoscale motor units that can drive directed motion against external load and perform at levels comparable to those of natural macromolecular motor proteins. Achieving this goal will create unprecedented technological opportunities, for example, to drive chemical synthesis, actively propel nanoscale drug- delivery vehicles, pump and separate molecules across barriers or package molecules into cargo components.", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["724261"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITEIT LEIDEN", "UNIVERSITEIT LEIDEN"], "EU_Contribution": ["EUR 1 475 565"], "Project_Title": ["Indigenous Knowledge in the Making of Science: Historia Naturalis Brasiliae (1648)"], "Total_Cost": ["EUR 1 475 565"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["BRASILIAE"], "Technology_Description": "This project is an interdisciplinary study of the role of indigenous knowledge in the making of science. Situated at the intersection of history and anthropology, its main research objective is to understand the transformation of information and practices of South American indigenous peoples into a body of knowledge that became part of the Western scholarly canon. It aims to explore, by means of a distinctive case-study, how European science is constructed in intercultural settings. ", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["715423"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 200 194,80"], "Project_Title": ["Novel Release-on-demand micronutrient fertilisers for crops"], "Total_Cost": ["EUR 200 194,80"], "Country": ["Denmark"], "Project_ACR": ["MicroFert"], "Technology_Description": "In many important agricultural crops successful fertilisation with micronutrients can lead to substantial increases in diseases resistance, marketable yield, and improved nutritional quality of food and feed. However, the plant availability of supplied micronutrients is usually too low due to the high reactivity of fertilisers under unfavourable soil conditions.", "To": ["2017-07-31, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-08-01"], "Project_ID": ["659999"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["The Brain Dynamics of Human Fluid Intelligence"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["NEUROINTELLIGENCE"], "Technology_Description": "Human fluid intelligence is characterized by a structured sequence of cognition, resulting in efficient application of rules to novel problems. In the brain, metabolic neuroimaging and lesion studies have linked fluid intelligence to a specific frontoparietal network, here called the multiple-demand (MD) network, comprising regions of lateral frontal, insular, dorsomedial frontal and parietal cortex. But how do MD functions determine fluid intelligence across stages of cognition? My extensive expertise in electroencephalography (EEG) source analyses and neural pattern classification techniques will allow me to assess time-resolved neural representations of novel rules in MD and perceptual cortex as a function of fluid intelligence, as well as the causal impact of MD cortex on earliest stages of perceptual encoding. Higher- and lower-intelligent subjects\u2019 electrophysiological (EEG) and behavioural measures of novel rule implementation will be systematically analysed. Non-invasive neural stimulation (transcranial magnetic stimulation (TMS)) will be used in combination with EEG to draw causal conclusions on the specific role of MD and perceptual cortices in human fluid intelligence. My novel analysis approach may provide a new account on fluid intelligence: one aspect of low fluid intelligence may be the dysfunctional early filtering of task-relevant information in perceptual cortex, due to lack of top-down control from MD cortices, leading to sensory overload on later processing stages. The proposal\u2019s outcomes will be both of high academic and commercial interest. Understanding the brain signatures underlying fluid intelligence is essential for more specific and cost-effective medical interventions. For example, decline of fluid intelligence due to healthy ageing is strongly correlated with high-cost medical conditions such as depression, which affect an increasing number of people in the ageing European population.", "To": ["2020-02-29, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["752276"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KATHOLIEKE UNIVERSITEIT LEUVEN", "KATHOLIEKE UNIVERSITEIT LEUVEN"], "EU_Contribution": ["EUR 1 386 875"], "Project_Title": ["Virtual building acoustics: a robust and efficient analysis and optimization framework for noise transmission reduction"], "Total_Cost": ["EUR 1 386 875"], "Country": ["Belgium", "Belgium"], "Project_ACR": ["VirBAcous"], "Technology_Description": "Achieving a sufficient sound insulation of buildings is a complex problem since multiple transmission paths are important, uncertainties can have a large effect, and acoustic performance requirements often conflict with structural and thermal requirements. Furthermore, accurate vibro-acoustic modelling across the entire building acoustics frequency range presently requires a huge computational effort. As a result, the acoustic development of building systems is usually based on general design rules, insufficiently accurate prediction models and many experimental prototype tests. Such development is costly and time consuming, and leads to suboptimal designs. This project therefore aims to develop an efficient yet sufficiently accurate prediction framework for the acoustic design of building systems which takes all uncertainties into account and which opens the way for design optimization. Four fundamental breakthroughs are required. First, a new approach to high-frequency subsystem modelling will overcome the limitations of the current statistical energy analysis paradigm and handle a high degree of geometric and material complexity. Second, a modelling framework for built-up systems will be developed, which incorporates different component model types and which switches between them as the frequency increases. The third development consists of quantifying the combined effect of all uncertain parameters on the overall sound insulation performance in a logically consistent and computationally efficient way. Finally, a robust optimization approach that spans the entire building acoustics frequency range and that accounts for all relevant non-acoustic performance criteria as well will be developed. Each development will be complemented by showcase applications in building acoustics, yet the fundamental nature of the developments make that they will have a profound impact in all disciplines where the study and/or control of mechanical wave propagation are important.", "To": ["2022-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["714591"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["THE UNIVERSITY OF EDINBURGH", "THE UNIVERSITY OF EDINBURGH"], "EU_Contribution": ["EUR 1 999 155"], "Project_Title": ["Classicising learning in medieval imperial systems: Cross-cultural approaches to Byzantine paideia and Tang/Song xue"], "Total_Cost": ["EUR 1 999 155"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["PAIXUE"], "Technology_Description": "In the medieval Eurasian geopolitical space, Byzantium and China stand out as two centralised imperial orders that drew on seemingly unbroken, in fact purposely constructed, traditions of classicising learning. PAIXUE examines in tandem, with equal focus on structural parallels and divergences, the conscious revival and subsequent dialectics of classicising learning in middle and later Byzantium (c.800\u20131350) and Tang/Song China (618\u20131279). Initially tied into aristocratic culture, it became a tool by which the imperial state sought to monopolise prestige and access to power so as to effectively channel the activities of newly emerging burgeoning \u2018middling\u2019 strata into the service of empire. As time progressed, it was also the basis upon which these new elites constructed novel forms of subjectivity that claimed authority and agency increasingly independent of the imperial state.", "To": ["2022-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["726371"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["THE UNIVERSITY OF WARWICK"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Tubular Supramolecular Polymer Brushes as Novel Therapeutic Materials"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["TSPBNTM"], "Technology_Description": "The aim of this project is to develop supramolecular polymer brushes through the self-assembly of cyclic peptide/polymer conjugates into functional materials for applications as therapeutic polymers. The research program is articulated around 1/the fabrication of supramolecular polymers of precisely controlled structures from peptide\u2013polymer conjugate synthesis to self-assembly and 2/applying these supramolecular polymers to build delivery vehicles for therapeutic applications.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["747931"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI SASSARI", "UNIVERSIDAD DE BURGOS", "HELMHOLTZ-ZENTRUM GEESTHACHT ZENTRUM FUR MATERIAL- UND KUSTENFORSCHUNG GMBH", "MONOLITHOS KATALITES KE ANAKIKLOSI ETAIREIA PERIORISMENIS EVTHINIS", "VLACHOS NIKOLAOS", "UNIVERSIDAD DE CHILE", "COMISION NACIONAL DE ENERGIA ATOMICA"], "EU_Contribution": ["EUR 702 000"], "Project_Title": ["CO2 absorbing Materials Project- RISE"], "Total_Cost": ["EUR 702 000"], "Country": ["Italy", "Spain", "Germany", "Greece", "Cyprus", "Chile", "Argentina"], "Project_ACR": ["CO2MPRISE"], "Technology_Description": "CO2MPRISE - Excellence training in solutions for CO2 capture technology aims to bring together subject matter experts from the academic and non-academic sectors to develop new technologies in CO2 capture and conversion field.", "To": ["2021-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2017-03-01"], "Project_ID": ["734873"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["THE UNIVERSITY OF EDINBURGH"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Extracellular vesicle-mediated delivery of long non-coding RNA: Implications for vascular repair and regeneration"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["EV-LNC"], "Technology_Description": "Background: The concept of extracellular vesicles (EVs) has drastically changed from the initial non-functional debris to the current of key mediators of paracrine signalling. The cargoes of EVs comprise all kinds of macromolecules, and recent evidence has demonstrated the presence of long non-coding RNAs (lncRNAs) in such vesicles. These RNA molecules have numerous potential regulatory functions and results obtained so far guide us to presume a determinant role in vascular cell differentiation, proliferation and repair. Besides, the increasing data emerging in the field are significantly changing the way in which we interpret molecular mechanisms driving cardiovascular diseases and offers a brand new set of molecular targets for therapy. For all these reasons, study of lncRNAs in vascular biology and disease is state-of-the-art. ", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["747287"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KATHOLIEKE UNIVERSITEIT LEUVEN", "KATHOLIEKE UNIVERSITEIT LEUVEN", "THE UNIVERSITY OF EDINBURGH", "THE REGENTS OF THE UNIVERSITY OF CALIFORNIA"], "EU_Contribution": ["EUR 1 810 576"], "Project_Title": ["The evolutionary dynamics of pathogen emergence and establishment: from Reservoir Detection to Outbreak Control"], "Total_Cost": ["EUR 1 810 576"], "Country": ["Belgium", "Belgium", "United Kingdom", "United States"], "Project_ACR": ["ReservoirDOCs"], "Technology_Description": "Extracted evolutionary and epidemiological information from pathogen genomes has grown into an important instrument across infectious disease research. By harnessing such information, molecular epidemiologists aim to shed light on the origin and epidemic history of pathogens, from reservoir dynamics to emergence and adaptation to new hosts, and their spatiotemporal spread. However, despite the revolution in genome sequencing technologies and advances in statistical methodology, key questions about pathogen emergence and establishment in human populations remain unresolved for major viral epidemics. When confronted with new viral outbreaks, such as the recent devastating Ebola virus epidemic, we also struggle to deploy these technologies in a systematic and concerted way despite a critical need to support public health interventions.", "To": ["2022-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["725422"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["LUNDS UNIVERSITET"], "EU_Contribution": ["EUR 173 857,20"], "Project_Title": ["Speciation and hybridization: a sex chromosome perspective"], "Total_Cost": ["EUR 173 857,20"], "Country": ["Sweden"], "Project_ACR": ["Hybrid Conflicts"], "Technology_Description": "How do new species arise and how do closely related species maintain their integrity despite hybridization? Notwithstanding the central position of these questions in the fields of evolutionary and conservation biology, few biologists have provided answers. Here, I will address these questions using a multidisciplinary approach combining genomics, lab experiments and field work. The key objectives of this project is to determine the factors that lead to genomic divergence between closely related and hybridizing species and characterise DNA sequence changes that are associated with pre- and postzygotic barriers to species exchange with emphasis on the role of the X chromosome. Training-through-research includes a secondment to another lab to improve skills in animal breeding and experiments. This action will also generate new resources to the scientific community (a damselfly genomics toolkit), and efficiently disseminate knowledge to the public. Due to its multidisciplinary approach and many opportunities for collaboration, executing this research program will provide new avenues of research for my future career as independent researcher within the EU. The excellent supervision and state of art infrastructure at the host lab will ensure the successful execution of this project.", "To": ["2020-02-29, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["753766"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 941 499"], "Project_Title": ["Metabolic Networks that Link Longevity to Reproduction in Response to Nutrition"], "Total_Cost": ["EUR 1 941 499"], "Country": ["France", "France"], "Project_ACR": ["MeLiLoN"], "Technology_Description": "In most western countries, life expectancy is increasing by 3 months a year. As the average age of the population increases, so too does the prevalence of age-related diseases such as cancer, cardiovascular and metabolic diseases, and neurodegenerative disorders. An essential component of ageing research is to understand the biological mechanisms that contribute to the ageing process at the cellular and molecular levels. This has major implications not only for the treatment of age-associated diseases but also for the promotion of healthy ageing.", "To": ["2020-09-30, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2015-10-01"], "Project_ID": ["647003"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["FUNDACIO INSTITUT DE CIENCIES FOTONIQUES"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Topological physics in tunable optical lattices"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["TOP-DOL"], "Technology_Description": "The project Topological physics with disorder in tunable optical lattices aims at developing a new experimental setup to explore topological material properties and topological quantum phase transitions using cold atoms in optical lattices.", "To": ["2017-05-31, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2015-06-01"], "Project_ID": ["657439"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Streamlined Functionalisation of Nitrogen-containing Molecules by Palladium-catalysed C-H Activation"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ACTPD"], "Technology_Description": "Transition-metal catalysed C-H activation is a powerful tool to functionalise and derivatize organic molecules at seemingly inert sites. The strategy opens new efficient synthetic routes to existing molecules and provides access to novel ones. Our aim is to develop palladium catalysed sp3 C-H activation technology for the synthesis of nitrogen heterocycles and for the derivatization of simple secondary amines to high value molecules. Our proposal will address demand in the pharmaceutical industry for the efficient synthesis of nitrogen-containing molecules to aid medicinal chemistry and accelerate the drug discovery processes.", "To": ["2019-03-09, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-03-10"], "Project_ID": ["747600"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Deep Earth Elastic Properties and Effective Rheology"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["DEEPER"], "Technology_Description": "The interface between the Earth\u2019s rocky mantle and molten outer core, located 2900 km below the surface, is marked by a patchwork of enigmatic structures. These structures, revealed by anomalous reductions in the speed of traveling seismic waves, are characterized by high density, partial melting, and low topographic heights (10-40 km above the core-mantle boundary). Due to the low seismic wave speeds, they are called UltraLow Velocity Zones (ULVZs). Since their \ufb01rst discovery in the 90s, our understanding of the ULVZs has been based on seismic observations. The in\ufb02uence of microscale distribution of melt and minerals on the seismic signature and the internal structure of the ULVZs remain a challenging question in geophysics. To address this question, this project will use a cross-scale approach to quantify the in\ufb02uence of partial melting and solid composition on the elastic properties and rheology of the UL-VZs based on a microstructural model. Using the microscale constraints on the physical properties, the km-scale internal structure of the ULVZs will be simulated using a \ufb01nite elements model.", "To": ["2017-07-29, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-07-30"], "Project_ID": ["658330"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["INSTITUT SUPERIEUR DE L'AERONAUTIQUE ET DE L'ESPACE"], "EU_Contribution": ["EUR 138 807"], "Project_Title": ["Designing Next-Generation Aircraft via High-Fidelity Computational Models and Optimization"], "Total_Cost": ["EUR 138 807"], "Country": ["France"], "Project_ACR": ["NextGen Airliners"], "Technology_Description": "Air transportation is a crucial contributor to the world economy, and thus its continued growth is essential. However, environmental impact and the increase in fuel prices make sustainable aviation a challenge. To address this challenge, we propose to develop state-of-the-art computational tools for the design optimization of next-generation airliners with unprecedented fuel efficiency. We will achieve this by leveraging the expertise of the researcher on high-fidelity computational design of aircraft, together with Airbus\u2019 vast experience in practical aircraft design, and the network of academics at ISAE. The proposed research is expected to make a lasting impact at Airbus by implementing new computational tools, and by developing design concepts for the next-generation of aircraft.", "To": ["2016-11-30, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-06-01"], "Project_ID": ["658570"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE JAMES HUTTON INSTITUTE", "THE JAMES HUTTON INSTITUTE", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSITY OF DUNDEE"], "EU_Contribution": ["EUR 1 978 475"], "Project_Title": ["Sensing soil processes for improved crop nitrogen bioavailability"], "Total_Cost": ["EUR 1 978 475"], "Country": ["United Kingdom", "United Kingdom", "France", "United Kingdom"], "Project_ACR": ["SENSOILS"], "Technology_Description": "Food production is predicated on the application of nitrogen fertilisers, which can contribute significantly to the production of greenhouse gasses and eutrophication of agroecosystems. The use of nitrogen fertilisers must, therefore, be optimised.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["647857"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["INSTITUT BARCELONA D ESTUDIS INTERNACIONALS, FUNDACIO PRIVADA"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Security Paradoxes in the Great Lakes: Between the Military-Capable and the Good-Governed State"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["PARADOXGREATLAKES"], "Technology_Description": "This project identifies security-governance paradoxes resulting from the European Union\u2019s (EU) security practices in the Great Lakes region. Although this region has been declared of strategic importance for the EU, several practices could undermine both the EU\u2019s security and normative foreign policy goals. Firstly, military and security measures, to which the EU has contributed extensively, have militarised the region, creating new sources of violence. Secondly, the aim to support military and security self-regulation could imply that the EU is transferring the attainment of security goals to the target states, thus losing some control and autonomy. Thirdly, though the EU has aimed to balance security and normative goals, scholars have questioned the extent to which a military and security-driven agenda is effective and whether it represents an abandonment of the good-governance agenda. Three questions follow from here: Is the practice of supporting military and security capacity undermining the good governance agenda? What implications does this have for EU\u2019s normative commitments? And, how effective is this practice for achieving EU\u2019s security goals? The research addresses and connects these debates through two specific innovations. It advances the concept of the \u2018military capable\u2019 state, and it proposes an innovative practice-based methodology to explore the implications of this concept by linking it to patterns of security practices in processes of intervention. Highlighting these paradoxes will offer important insights into the interconnection of security and normative goals in policy and implementation.", "To": ["2017-09-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["660933"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION"], "EU_Contribution": ["EUR 175 419,60"], "Project_Title": ["Circuit analysis of thalamic visual processing and its modulation by long-range projections"], "Total_Cost": ["EUR 175 419,60"], "Country": ["Switzerland"], "Project_ACR": ["Thalamic Circuits"], "Technology_Description": "The thalamus, whose anatomical history goes back two millenia, has long been recognized as the master relay for sensory information propagating to cortex and consciousness. Yet, it is indisputable that thalamic nuclei are much more than simple relays but integrate different sensory modalities, bottom-up as well as top-down information. One elementary form of top-down modulation is attention, which selectively enhances behaviorally relevant information. Attentional modulation occurs already at the thalamus by, yet, unresolved circuit mechanisms. My research specifically aims at (1) exploring circuits for long-range, top-down modulation of thalamic visual processing, (2) dissecting the circuitry underlying attentional modulation, and (3) understanding basic rules of thalamic information processing. I will pursuit these three aims using an innovative combination of monosynaptic retrograde rabies tracing, optogenetics and deep 2-photon calcium imaging. My experiments will focus on the lateral geniculate nucleus (LGN), which is the main connection between the optic nerve and the visual cortex, as well as on the thalamic reticular nucleus (TRN), which provides major inhibitory input to LGN and has previously been implicated in attentional regulation. Notably, TRN deficits have been suggested to contribute to the clinical symptoms of schizophrenia. By rabies tracing, I will target channelrhodopsin to monosynaptic long-range inputs to the visual thalamus. By GRIN-lens assisted 2-photon imaging I will quantify visual responses and search for signatures of attentional modulation that can be induced by optogenetic stimulation of specific inputs. This approach will allow me to quantify attentional modulation of thalamic information-processing by specific long-range inputs, to dissect the underlying circuitry mechanisms and to contribute to a better understanding of thalamic computational power as well as its vulnerabilities.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["707522"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITY OF NEWCASTLE UPON TYNE"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Sacred Landscapes in Late Byzantium"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SLLB"], "Technology_Description": "This interdisciplinary project will explore texts composed by the fourteenth-century Constantinopolitan Patriarch Philotheos Kokkinos, with a threefold focus on:", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["752292"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF WARWICK", "THE UNIVERSITY OF WARWICK", "SABANCI UNIVERSITESI"], "EU_Contribution": ["EUR 938 184"], "Project_Title": ["Exposure to Political Violence and Individual Behavior"], "Total_Cost": ["EUR 938 184"], "Country": ["United Kingdom", "United Kingdom", "Turkey"], "Project_ACR": ["EXPOVIBE"], "Technology_Description": "This project will explore how exposure to political violence in a civil conflict context impacts upon social, economic and political behavior of individuals. It has three legs. In the first leg I will analyze the association between political and domestic violence. Specifically, I will test the hypothesis that those exposed to political violence are more likely to be perpetrators of domestic violence. In the second leg I will analyze whether exposure to political violence impacts upon economic behavior. Specifically, I will analyze the impact of exposure on risk, time and social preferences, savings behavior, employment, and earnings. Finally, in the third leg I will look into political behavior. Specifically, I will analyze the association between exposure to political violence and political participation and support, political tolerance, ideology, voting behavior, and party choice. The project will make use of a natural experiment setting that the institutional setup and the long-running civil conflict in Turkey create. Turkey has a mandatory military service system that requires each Turkish man, when he comes to age, to serve in the army for about a year. Those drafted are first subject to a basic training program and then, via a lottery, are randomly assigned to military bases all over the country to serve the rest of their terms. This means a young soldier can be sent to a military base in Eastern or Southeastern Turkey where a bloody armed conflict between the Turkish armed forces and the insurgent organization PKK has been going on since August 1984, and thus, can get actively involved in the armed conflict. This is a natural experiment setting that randomly exposes young Turkish males to political violence. In this project I aim to study whether and how that exposure impacts upon social, economic and political behavior of the exposed. To accomplish these goals, two independent, large-n survey studies will be designed and conducted in Turkey.", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["677627"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION"], "EU_Contribution": ["EUR 175 419,60"], "Project_Title": ["Transcription factor binding as a function of chromatin"], "Total_Cost": ["EUR 175 419,60"], "Country": ["Switzerland"], "Project_ACR": ["TFtoChromatin"], "Technology_Description": "How the genomic blueprint of an organism is translated into cellular phenotype is a fundamental question in modern biology. The instructions need to be specifically regulated for cells to function. The regulation of the readout of this information is not entirely written in the DNA sequence but also requires epigenetic directives like DNA and histone modifications.", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Research Organisations"], "From": ["2017-08-01"], "Project_ID": ["705354"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION"], "EU_Contribution": ["EUR 175 419,60"], "Project_Title": ["Studying the role of the retrosplenial cortex in flexible learning"], "Total_Cost": ["EUR 175 419,60"], "Country": ["Switzerland"], "Project_ACR": ["REFLEX"], "Technology_Description": "An emerging view of cortical area function posits that instead of primarily accounting for sensory processing and motor control, cortical areas might mediate flexible handling of sensory information and motor planning through learning and memory. In this project I propose to investigate this notion focusing on the function of retrosplenial cortex (RSC), a large, poorly understood and highly interconnected cortical area that interfaces with the hippocampal system. RSC has a key role in memory, and is thought to control flexible use of contextual information; it accounts for earliest memory deficits in Alzheimer\u2019s disease. ", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Research Organisations"], "From": ["2016-09-01"], "Project_ID": ["707047"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITE DE BORDEAUX", "INSTITUT POLYTECHNIQUE DE GRENOBLE", "UNIVERSIDADE DE AVEIRO", "UNIVERSITE DU LUXEMBOURG", "UNIVERSITE DE LIEGE", "UNIVERSITE CATHOLIQUE DE LOUVAIN", "TECHNISCHE UNIVERSITAT DARMSTADT", "KARLSRUHER INSTITUT FUER TECHNOLOGIE", "LUXEMBOURG INSTITUTE OF SCIENCE AND TECHNOLOGY"], "EU_Contribution": ["EUR 3 779 224,56"], "Project_Title": ["European Joint Doctorate in Functional Materials Research"], "Total_Cost": ["EUR 3 779 224,56"], "Country": ["France", "France", "Portugal", "Luxembourg", "Belgium", "Belgium", "Germany", "Germany", "Luxembourg"], "Project_ACR": ["EJD-FunMat"], "Technology_Description": "EJD-FunMat is a European Joint Doctoral programme in the field of functional materials research. ", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-EJD - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-EJD)"], "Funding_scheme": ["MSCA-ITN-EJD - European Joint Doctorates"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2015-06-01"], "Project_ID": ["641640"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION", "FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION"], "EU_Contribution": ["EUR 2 499 604"], "Project_Title": ["Writing and editing of memories from acquisition to long-term consolidation"], "Total_Cost": ["EUR 2 499 604"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["MemoryDynamics"], "Technology_Description": "Nervous systems produce adaptive behavior, arguably their most important function, through learning and memory. Memories ensure that what is learned will be available for later retrieval. Upon the initial learning process, synaptic plasticity important for memory consolidation is triggered within minutes, but whether, and in which form memories will be retained more permanently can be influenced by information and insights gained after the initial trigger. Learning and memory have been studied extensively, but we still know very little about the mechanisms through which memories are shaped after acquisition. Here we hypothesize that instead of simply reflecting requirements to produce long-term memory traces, cascades of plasticity processes induced at the time of acquisition might also reflect systems requirements for updating of new relevant information, as well as selection of potentially useful memories that need to enter the process of long-term consolidation.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2016-10-01"], "Project_ID": ["694086"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI MILANO", "UNIVERSITA DEGLI STUDI DI MILANO", "TECHNISCHE UNIVERSITAT DARMSTADT"], "EU_Contribution": ["EUR 2 409 209"], "Project_Title": ["Noninvasive Manipulation of Gating in Ion Channels"], "Total_Cost": ["EUR 2 409 209"], "Country": ["Italy", "Italy", "Germany"], "Project_ACR": ["noMAGIC"], "Technology_Description": "noMAGIC has the visionary goal of engineering genetically encoded ion channels, which can be remotely controlled (gated) by stimuli that penetrate deep into human tissue without negative side effects. The control over ion channel activity by deep penetrating stimuli will revolutionize research in neurobiology and physiology as it paves the way for remote and genuine non-invasive control of cell activity in vivo. Synthetic channels, which can be gated by magnetic fields (MF), near infrared (NIR) radiation or ultrasound (US) will be engineered in the frame of noMAGIC by three complementary work packages (WP1-3). Design and engineering of the channels will be performed in WP1 by reiterated steps of rational and irrational design, high throughput screening and in vitro and in vivo functional testing. We have identified two sensor modules for MF and NIR radiation, respectively, which will be functionally connected to a channel pore for a remote control of gating. For the US-gated channel we will engineer a channel pore that is maximally responding to local changes in the lipid environment induced by US. Design and engineering of channels will be complemented by a computational approach (WP2), which analyses, from elastic network models, the mechanical connections in the channel pore and which extracts information on the forces, which are required to gate a channel by the three stimuli. The outcome of WP2 will provide general design rules for synthetic channels with implications much beyond the present project. WP3 also contributes to the engineering effort in WP1 by a spectrum of avant-garde spectroscopic methods, which resolve structural changes of the channel proteins under the influence of remote stimuli. These structural insights will greatly advance our understanding of structure/function correlates in composite ion channels and it will inspire the design and engineering of channels, which respond to remote stimuli.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["695078"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON", "UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 2 495 563"], "Project_Title": ["The origins of dendritic computation within mammalian neural circuits"], "Total_Cost": ["EUR 2 495 563"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["DENDRITECIRCUITS"], "Technology_Description": "This proposal aims to address a simple question: what is the fundamental unit of computation in the brain? Answering this question is crucial not only for understanding how the brain works, but also if we are to build accurate models of brain function, which require abstraction based on identification of the essential elements for carrying out computations relevant to behaviour. In this proposal, we will build on recent work demonstrating that dendrites are highly electrically excitable to test the possibility that single dendritic branches may act as individual computational units during behaviour, challenging the classical view that the neuron is the fundamental unit of computation. We will address this question using a combination of electrophysiolgical, anatomical, imaging, molecular, and modeling approaches to probe dendritic integration in pyramidal cells and Purkinje cells in mouse cortex and cerebellum.", "To": ["2021-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-07-01"], "Project_ID": ["695709"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["TECHNISCHE UNIVERSITAT DARMSTADT", "TECHNISCHE UNIVERSITAT DARMSTADT"], "EU_Contribution": ["EUR 1 405 572,50"], "Project_Title": ["Policy Learning of Motor Skills for Humanoid Robots"], "Total_Cost": ["EUR 1 405 572,50"], "Country": ["Germany", "Germany"], "Project_ACR": ["SKILLS4ROBOTS"], "Technology_Description": "The goal of SKILLS4ROBOTS is to develop a autonomous skill learning system that enables humanoid robots to acquire and improve a rich set of motor skills. This robot skill learning system will allow scaling of motor abilities up to fully anthropomorphic robots while overcoming the current limitations of skill learning systems to only few degrees of freedom. To achieve this goal, it will decompose complex motor skills into simpler elemental movements \u2013 called movement primitives \u2013 that serve as building blocks for the higher-level movement strategy and the resulting architecture will be able to address arbitrary, highly complex tasks \u2013 up to robot table tennis for a humanoid robot. Learned primitives will be superimposed, sequenced and blended. ", "To": ["2020-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-07-01"], "Project_ID": ["640554"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["TECHNISCHE UNIVERSITAT DARMSTADT", "TECHNISCHE UNIVERSITAT DARMSTADT"], "EU_Contribution": ["EUR 1 446 875"], "Project_Title": ["The origin of heavy elements: a nuclear physics and astrophysics challenge"], "Total_Cost": ["EUR 1 446 875"], "Country": ["Germany", "Germany"], "Project_ACR": ["EUROPIUM"], "Technology_Description": "Where in the universe are heavy elements synthesized? How are these elements produced? These are two exciting and interdisciplinary questions in nuclear astrophysics today and will be investigated in my ERC project EUROPIUM. The favored astrophysical sites are neutrino-driven winds following core-collapse supernovae and neutron star mergers, where extreme conditions enable the rapid neutron capture process (r-process). We will perform long-time multidimensional simulations of these two scenarios and combine them with nucleosynthesis calculations. In neutron star mergers, the radioactive decay of neutron-rich nuclei triggers an electromagnetic signal known as kilonova. This was potentially observed in 2013 after a short gamma ray burst, associated with a neutron star merger. We will simulate the neutrino- and viscous-driven ejecta from the disk that forms after the merger around the central compact object. In addition, we will investigate supernova neutrino-driven winds that produce lighter heavy elements from strontium to silver. We will explore the impact of rotation, improved microphysics, and magnetic fields on the wind evolution and nucleosynthesis. Because the synthesis of lighter heavy elements elements occurs closer to stability, the nuclear physics uncertainties will be reduced by experiments in the near future. This will uniquely allow us to combine observations and nucleosynthesis calculations to constrain the astrophysical conditions and gain new insights into core-collapse supernovae. In nuclear physics, a new era for extreme neutron-rich isotopes is starting with new experimental facilities. Based on our simulations, we will study the impact of the nuclear physics input (nuclear masses, beta decays, neutron captures, and fission) going beyond the state-of-the-art by providing r-process abundances with uncertainties. Comparing our results with forefront observations of the oldest stars will in turn provide new insights about the origin of heavy elements.", "To": ["2021-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["677912"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION", "FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION"], "EU_Contribution": ["EUR 2 200 677"], "Project_Title": ["The molecular basis of CULLIN E3 ligase regulation by the COP9 signalosome"], "Total_Cost": ["EUR 2 200 677"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["CsnCRL"], "Technology_Description": "Specificity in the ubiquitin-proteasome system is largely conferred by ubiquitin E3 ligases (E3s). Cullin-RING ligases (CRLs), constituting ~30% of all E3s in humans, mediate the ubiquitination of ~20% of the proteins degraded by the proteasome. CRLs are divided into seven families based on their cullin constituent. Each cullin binds a RING domain protein, and a vast repertoire of adaptor/substrate receptor modules, collectively creating more than 200 distinct CRLs. All CRLs are regulated by the COP9 signalosome (CSN), an eight-protein isopeptidase that removes the covalently attached activator, NEDD8, from the cullin. Independent of NEDD8 cleavage, CSN forms protective complexes with CRLs, which prevents destructive auto-ubiquitination. ", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2016-01-01"], "Project_ID": ["666068"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION", "FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION"], "EU_Contribution": ["EUR 2 136 969"], "Project_Title": ["Readout of DNA methylation"], "Total_Cost": ["EUR 2 136 969"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["ReaDMe"], "Technology_Description": "DNA and chromatin modifications are essential for proper control of gene expression during development. How these marks alter transcriptional programs and modulate binding patterns of sequence specific transcription factors (TF) remains poorly understood. This currently limits our interpretation of epigenomic maps towards their incorporation into predictive models of gene regulation.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2016-01-01"], "Project_ID": ["667951"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION", "FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION"], "EU_Contribution": ["EUR 1 998 557"], "Project_Title": ["RNAi-mediated Epigenetic Gene Regulation"], "Total_Cost": ["EUR 1 998 557"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["REpiReg"], "Technology_Description": "RNAi refers to the ability of small RNAs to silence expression of homologous sequences. A surprising link between epigenetics and RNAi was discovered more than a decade ago, and I was fortunate enough to be involved in this exciting field of research from the beginning. It is now well established that endogenous small RNAs have a direct impact on the genome in various organisms. Yet, the initiation of chromatin modifications in trans by exogenously introduced small RNAs has been inherently difficult to achieve in all eukaryotic cells. This has sparked controversy about the importance and conservation of RNAi-mediated epigenome regulation and hampered systematic mechanistic dissection of this phenomenon.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-01-01"], "Project_ID": ["681213"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["TECHNISCHE UNIVERSITAT DARMSTADT", "TECHNISCHE UNIVERSITAT DARMSTADT"], "EU_Contribution": ["EUR 1 999 465"], "Project_Title": ["Enhancing electrocatalysis in low temperature fuel cells by ionic liquid modification"], "Total_Cost": ["EUR 1 999 465"], "Country": ["Germany", "Germany"], "Project_ACR": ["IL-E-CAT"], "Technology_Description": "The commercialization of low temperature fuel cells is restricted by the high cost and low durability of cathode catalysts. Intense efforts have been devoted to tackle this issue by engineering the structure of Pt-based catalysts. Herein, a novel concept towards enhancing the performance of low temperature fuel cell catalysts is proposed, namely by tuning the local active site microenvironment with an immobilized ionic liquid (IL) phase. As demonstrated by the applicant in preliminary work, a suitable IL layer strongly influences the active catalytic site in a very promising manner, apparently via a highly complex interplay of solvent-, ligand- and electrostatic-stabilization effects. As the structural versatility of ILs allows for rational engineering of this modification at molecular level, the proposed project aims for a full scientific exploration of the remarkable activation and stabilization effects in ORR, to enable the realization of an innovative fuel cell cathode with dramatically enhanced performance. To achieve this ambitious goal, a sound fundamental understanding of the interaction of ILs with electrocatalytic sites will be derived by making use of the excellent research infrastructure and longstanding experience in ionic liquid design and catalytic materials at our institute. To demonstrate the general applicability, the deduced principals will also be applied to CO2 electrochemical reduction. The approach will not stop at the design of novel catalyst systems, but will address solutions to ensure long-term stability of the IL modification. To avoid IL leaching from the catalyst over time, the recent success of the applicant in the synthesis of novel core/shell carbon materials will be employed. The IL will be synthesized in situ within a mesoporous core and the steric demanding ions fixed through a molecular sieving shell surrounding each catalyst particle. A model-assisted strategy will be applied for optimization of the core/shell pore structures.", "To": ["2021-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["681719"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION", "FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION"], "EU_Contribution": ["EUR 2 500 000"], "Project_Title": ["The interpretation of retinal activity by the visual thalamus."], "Total_Cost": ["EUR 2 500 000"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["RETMUS"], "Technology_Description": "Sensory systems of the brain inform cortical centers about the outside world via the thalamus. Despite its central location between the sensory periphery and the primary sensory cortex, the functional role of the thalamus in sensory processing is still largely unknown. Understanding the role of thalamic circuits and their modulation by other brain areas is important for several reasons. First, in order to dissect the functional role of higher brain regions, such as sensory cortical areas, it is critical that we understand what kind of input they receive from the thalamus. The thalamus takes information from several different sensory channels, carrying different sensory features. Whether these features are simply relayed to higher centers, or perhaps recombined into new features in the thalamus, is not known. Second, as a central station in sensory processing, the thalamus is thought to gate behaviorally relevant sensory information. In addition to the input from the sensory periphery, the thalamus receives input from several other brain regions. How these inputs modulate or gate sensory information in vivo is not well understood. Finally, in the case of the visual system, an important unmet medical need is optic nerve degeneration caused by end-stage glaucoma, which leads to blindness. Here the input to thalamus is lost, yet the thalamic and cortical circuits are not severely affected. New methods to reactivate the thalamic neurons by channeling visual information directly to these neurons may help to restore some visual capability after the loss of optic nerve fibers.", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2015-11-01"], "Project_ID": ["669157"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["THE JAMES HUTTON INSTITUTE", "THE JAMES HUTTON INSTITUTE"], "EU_Contribution": ["EUR 2 499 980"], "Project_Title": ["Recombination in large genome crop plants"], "Total_Cost": ["EUR 2 499 980"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["SHUFFLE"], "Technology_Description": "During meiosis, recombination (crossing-over, CO) drives the exchange of genetic materials and releases genetic diversity by creating new combinations of alleles within and among chromosomes. CO is exploited in plant breeding through the generation of large populations of recombinants from which genetically improved individuals are selected. However in some economically important crops such as barley, the rate of improvement has plateaued. One hypothesis is that this is due to constraints on the locations of CO. In large genome cereals CO is restricted to the ends of chromosomes, excluding approximately two thirds of the genome from the breeding process.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2015-10-01"], "Project_ID": ["669182"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION", "FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION"], "EU_Contribution": ["EUR 2 497 200"], "Project_Title": ["Amygdala Circuits for Appetitive Conditioning"], "Total_Cost": ["EUR 2 497 200"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["Amygdala Circuits"], "Technology_Description": "The project outlined here addresses the fundamental question how the brain encodes and controls behavior. While we have a reasonable understanding of the role of entire brain areas in such processes, and of mechanisms at the molecular and synaptic levels, there is a big gap in our knowledge of how behavior is controlled at the level of defined neuronal circuits.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2016-01-01"], "Project_ID": ["669582"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION", "FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION"], "EU_Contribution": ["EUR 2 859 560"], "Project_Title": ["Transcriptional and Epigenetic Regulation of Totipotency in Mouse Early Embryos."], "Total_Cost": ["EUR 2 859 560"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["Totipotency"], "Technology_Description": "In mammals, fusion of two highly differentiated gametes gives rise to a totipotent zygote capable of developing into a whole organism. It coincides with translation and degradation of maternally provided transcripts, initiation of global transcription called zygotic genome activation (ZGA), and \u201cepigenetic reprogramming\u201d of germline chromatin states into an embryonic state. The molecular mechanisms underlying this exquisite reprogramming of cell fate are barely understood. ", "To": ["2021-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2016-08-01"], "Project_ID": ["695288"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN", "ROYAL COLLEGE OF SURGEONS IN IRELAND"], "EU_Contribution": ["EUR 175 866"], "Project_Title": ["Development of a chemotherapeutic gel for glioblastoma multiforme treatment"], "Total_Cost": ["EUR 175 866"], "Country": ["Ireland", "Ireland"], "Project_ACR": ["THERAGEL"], "Technology_Description": "Advanced nanotechnology-based materials offer new solutions to the challenges associated with the non-specific delivery of therapeutics that leads to ineffective treatments, especially in oncology. Currently, both therapeutic and diagnostic molecules are administered systemically, increasing the likelihood of unwanted side effects. THERAGEL will develop a novel delivery system that enables selective, targeted local delivery of therapeutics and imaging agents. Specifically, I will use this delivery system to design a therapy for the treatment of glioblastoma multiforme, the most aggressive form of brain cancer. THERAGEL will comprise a unique combination of advanced injectable polymeric depots and targeted nanoparticles with both chemotherapeutic and imaging agent payloads (\u2018theranostic\u2019 nanoparticle). The polymeric depots will provide a continuous release of free chemotherapeutic drug, with a tunable profile depending on the polymer composition, and cancer-targeted nanoparticles that will release the theranostic cargo only after selective uptake by cancer cells. THERAGEL will advance the state of the art in nanomedicines through advances to the individual components of the developed delivery system. This proposal represents a unique opportunity in the context of nanotheranostics for tailored chemotherapy, and means a significant step towards its clinical translation. The technologies developed will address three out of the six Horizon 2020 Key Enabling Technologies themes, which are a key part of the programme funding strategy: Nanotechnology, Advanced Biomaterials and Advanced Manufacturing technologies. This research constitutes a highly multidisciplinary approach with large impact in near future advanced therapies and with a great chance for collaboration and networking between European research groups and industrial partners. Combining my expertise in gated-materials with the host PI\u2019s delivery systems development experience will make this new direction possible", "To": ["2018-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-04-01"], "Project_ID": ["708036"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["RISE RESEARCH INSTITUTES OF SWEDEN AB"], "EU_Contribution": ["EUR 173 857,20"], "Project_Title": ["Energy innovative food process for production of high quality frozen foods"], "Total_Cost": ["EUR 173 857,20"], "Country": ["Sweden"], "Project_ACR": ["COLDmicroWAVE"], "Technology_Description": "COLD\u00b5WAVE aims to improve the research skills of Epameinondas Xanthakis by developing an innovative environmentally sustainable process for blanching and freezing vegetables with improved textural and nutritional quality at SP -Technical Research Institute of Sweden. The study which will be carried out will involve the use of microwave electromagnetic irradiation (MW) for blanching and freezing of vegetables. COLD\u00b5WAVE will develop tailored equipment for MW blanching of vegetables that has very high energy efficiency and no water consumption. Furthermore, this project will develop innovative pathways in freezing to improve the quality of frozen vegetables by exploring, in a new context, previous results acquired by the fellow. The developed process will lead to improved quality characteristics compared to the conventional freezing. During this extensive study the fellow will gain valuable multidisciplinary experience and new theoretical and practical skills in the areas of heat transfer modelling, energy accounting methods, food nutrition and quality measurements as well as life cycle assessment methods. The integrated proposed study will give the fellow the opportunity to develop further knowledge on development of innovative processes having industrial importance and finally become a real specialist in the microwave assisted food blanching and freezing. The candidate will also learn to conduct research, to manage projects, communicate results effectively, commercialise research, as well as an in-depth education in development of innovative processes which will contribute for an open mind to innovation and more successfully realisation of research ideas into commercial reality.", "To": ["2017-04-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Research Organisations"], "From": ["2015-05-01"], "Project_ID": ["660067"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["TECHNISCHE UNIVERSITAT DARMSTADT"], "EU_Contribution": ["EUR 219 693,60"], "Project_Title": ["ACcelerating Transition in Peri-Urban areaS in East Africa"], "Total_Cost": ["EUR 219 693,60"], "Country": ["Germany"], "Project_ACR": ["ACTUS"], "Technology_Description": "Behind statements and statistics about newly urbanized populations in Africa, behind maps of rapid and unregulated growth and numerous disaster/risk assessments there are real people with compelling tales of coping and adapting capacities to urban challenges brought by the rapid transformation of cities. Their stories often contain more hope, ambition and imagination as portrayed in reports and scientific publications. Their ability to bounce back despite disadvantageous ecological, economic and political settings implies a new form of normality framed outside traditional city development models.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["657784"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE JAMES HUTTON INSTITUTE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["The mechanism of acquired thermotolerance in potato"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ACQUIRE"], "Technology_Description": "For many commercial potato cultivars, tuber yield is optimal at average day time temperatures in the range of 14-22\u02daC. Further rises in ambient temperature can reduce or completely inhibit potato tuber production, with damaging consequences for both producer and consumer. Despite centuries of potato breeding, high temperature tolerance has not been significantly improved. Targeted breeding approaches are hampered by a lack of knowledge on the molecular mechanisms of how plants perceive and translate high temperature into relevant acclimation responses. Although in recent research we have identified genotypes that can yield well under elevated temperatures, we have not yet dissected which responses to elevated temperature are the most critical for yield. Thus the objectives of ACQUIRE are: to develop a robust screen to assay for acquired thermotolerance in potato; to test potato genotypes and transgenic lines for variation in the acquired thermotolerance response; to determine transcriptional and metabolite profiles associated with acquired thermotolerance; to introgress beneficial alleles of a potato heat tolerance gene (StHot1) to develop Nearly Isogenic Lines with improved acquired thermotolerance characteristics; to assess the impact of acquired thermotolerance on tuber yield in a range of genotypes. The project will serve a training vehicle for an experienced researcher to enhance her portfolio of research skills and so increase their ability to innovate in this important area of food security. The experienced worker will add an extra dimension to current research activities in the host organisation by sharing her current expertise. The outcomes will be of commercial and societal interest and a raft of measures will be taken to ensure thorough dissemination of the project activities. The project will leave the experienced worker well-qualified to achieve professional maturity and will have a legacy of collaboration and new research avenues to be explored.", "To": ["2018-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations"], "From": ["2016-05-01"], "Project_ID": ["702121"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["TECHNISCHE UNIVERSITAT DARMSTADT", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "FUNDACIO INSTITUT DE CIENCIES FOTONIQUES", "THE QUEEN'S UNIVERSITY OF BELFAST", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "WEIZMANN INSTITUTE OF SCIENCE", "LUPHOS GMBH", "FASTLITE SARL"], "EU_Contribution": ["EUR 2 338 562,16"], "Project_Title": ["High-Intensity Coherent Nonlinear Optics"], "Total_Cost": ["EUR 2 338 562,16"], "Country": ["Germany", "United Kingdom", "Spain", "United Kingdom", "United Kingdom", "Israel", "Germany", "France"], "Project_ACR": ["HICONO"], "Technology_Description": "Optical laser-based technologies are a key technology of the 21st century. Extension of the range of scientific and commercial laser applications requires a constant expansion of the accessible regimes of laser operation. Concepts from nonlinear optics, driven with ultra-fast lasers provide all means to achieve this goal. However, nonlinear optics typically suffer from low efficiencies, e.g. if high-order processes are involved or if the driving laser pulse intensities must be limited below damage thresholds (e.g. in nonlinear microscopy of living cells, or nonlinear spectroscopy of com-bustion processes). Hence, we require methods to enhance nonlinear optical processes. The field of \u201ccoherent control\u201d provides techniques to manipulate laser-matter interactions. The idea is to use appropriately designed light-matter interactions to steer quantum systems towards a desired out-come, e.g. to support nonlinear optical processes.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-10-01"], "Project_ID": ["641272"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["FUNDACAO DA FACULDADE DE CIENCIAS DA UNIVERSIDADE DE LISBOA FP"], "EU_Contribution": ["EUR 220 882,50"], "Project_Title": ["BIHC- Bio-inspired models of human crowds"], "Total_Cost": ["EUR 220 882,50"], "Country": ["Portugal"], "Project_ACR": ["BIHC"], "Technology_Description": "With current consumer-grade personal computers, it is possible to display 3d virtual scenes with thousands of animated individual entities at interactive frame rates. Crowd simulations are, however, too often limited to characters lacking individuality and wandering in an environment without a specific goal. This situation is particularly problematic in the field of cultural heritage in real-time simulations of the past where the realism of individual behavior is critical. This proposal, through a collaboration across the computer science and the archaeology fields, seeks to address this problem. It aims at exploring bio-mimicking techniques in the development of a generative model for heterogeneity and spontaneity in behavioral animation of crowds. More specifically, the goals can be defined as (i) the development of a bio-inspired model of agency for virtual humans (which upgrades a previous prototype, part of my earlier research), (ii) the development of an authoring tool to interact with the parameters of that model and develop context-specific behaviors/animations, and finally (iii) the development of a proof-of-concept - the simulation of a historical environment, with the assistance of non-programmers using the authoring tool developed earlier.", "To": ["2017-12-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Portugal"], "Activity": ["Research Organisations"], "From": ["2015-07-01"], "Project_ID": ["655226"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSIDAD DE GRANADA"], "EU_Contribution": ["EUR 2 124 000"], "Project_Title": ["Attracting and Encouraging Triple I Talent Mobility"], "Total_Cost": ["EUR 4 248 000"], "Country": ["Spain"], "Project_ACR": ["Athenea3I"], "Technology_Description": "Athenea3I is an innovative regional wake-up call focused on attracting highly talented researchers to Granada (Andalusia region, Spain) in order to benefit their research career with International, Interdisciplinary and Intersectorial opportunities. This innovative fellowship programme offers the experienced researchers an outstanding opportunity to develop new skills and competences, enriched with a personalized and pioneering career mentoring plan. It also includes research periods at some of the most distinguished outstanding institutions around the world, and optional secondments in regional, national and international companies.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2016 - Co-funding of regional, national and international programmes"], "Funding_scheme": ["MSCA-COFUND-FP - Fellowship programmes"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["754446"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2016"]}, -{"Partners": ["AALBORG UNIVERSITET"], "EU_Contribution": ["EUR 627 840"], "Project_Title": ["FrontierResearchCompentences@CNAP"], "Total_Cost": ["EUR 1 255 680"], "Country": ["Denmark"], "Project_ACR": ["FRESCOatCNAP"], "Technology_Description": "Chronic pain is a key societal challenge affecting one out of five adults and is in general poorly treated. This programme, FrontierResearchCompentences@CNAP (FRESCO@CNAP), aims to install 8 early stage researchers (ESRs) in a Centre-of-Excellence (CNAP) conducting frontline research on novel tools for identifying and modulating human pain mechanisms. ", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2016 - Co-funding of regional, national and international programmes"], "Funding_scheme": ["MSCA-COFUND-DP - Doctoral programmes"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["754465"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2016"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI SALERNO", "TECHNISCHE UNIVERSITEIT DELFT", "UNIVERSIDADE DO MINHO", "FUNDACION TECNALIA RESEARCH & INNOVATION", "GESELLSCHAFT FUER MATERIALFORSCHUNG UND PRUEFUNGSANSTALT FUER DAS BAUWESEN LEIPZIG MBH", "TECHNISCHE UNIVERSITAT DARMSTADT"], "EU_Contribution": ["EUR 468 000"], "Project_Title": ["SUstainability-driven international/intersectoral Partnership for Education and Research on modelling next generation CONCRETE"], "Total_Cost": ["EUR 504 000"], "Country": ["Italy", "Netherlands", "Portugal", "Spain", "Germany", "Germany"], "Project_ACR": ["SUPERCONCRETE"], "Technology_Description": "SUPERCONCRETE is a synergetic cross-disciplinary international/intersectoral project addressing theoretical models for next-generation concretes, characterised by a significant sustainability enhancement for the construction industry. ", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2015-07-01"], "Project_ID": ["645704"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["RIJKSUNIVERSITEIT GRONINGEN", "MEDICAL RESEARCH COUNCIL", "RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN", "DANMARKS TEKNISKE UNIVERSITET", "THE UNIVERSITY OF WARWICK", "TECHNISCHE UNIVERSITAT DARMSTADT", "INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE", "KOBENHAVNS UNIVERSITET", "BIOSYNTIA APS", "DSM FOOD SPECIALTIES BV", "THE FRANCIS CRICK INSTITUTE LIMITED"], "EU_Contribution": ["EUR 3 995 643,24"], "Project_Title": ["RNA-based technologies for single-cell metabolite analysis"], "Total_Cost": ["EUR 3 995 643,24"], "Country": ["Netherlands", "United Kingdom", "Germany", "Denmark", "United Kingdom", "Germany", "France", "Denmark", "Denmark", "Netherlands", "United Kingdom"], "Project_ACR": ["MetaRNA"], "Technology_Description": "Metabolism is the foundation of all living organisms. While cells in a population are often phenotypically different, most of our current analytical approaches still probe metabolism only at the population level. Because strong evidence exists that metabolic cell-to-cell heterogeneity has, for instance, disease relevance, researcher from MetaRNA will overcome this severe analytical limitation through exploiting exciting opportunities emerging from the RNA field. Such synergy potential between the metabolism and RNA research fields has until today not been exploited, because they are separated from each other in Europe and worldwide. Through consequently missing research training programs we thus lack experts with combined knowledge in metabolism and RNA. The aim of the MetaRNA proposal is therefore to establish a European Training Network (ETN) that educates specialists for academia and industry - fully trained at the interface of these two fields - in the development and application of RNA-based sensors to investigate metabolism at the single-cell level, to apply these tools for novel biotechnological applications and to provide a framework for their future use in diagnostics and therapeutics. In MetaRNA, eight research groups from the metabolic and RNA fields and six partners from the private sector join forces to create a platform of mobility and training to 15 early-stage researchers (ESRs), by means of customized research projects, exchange of knowhow among researchers and partners, attendance to specialized courses, workshops and conferences, as well as training in complementary skills.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations"], "From": ["2015-01-01"], "Project_ID": ["642738"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION", "FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION"], "EU_Contribution": ["EUR 2 500 000"], "Project_Title": ["Control of Action Diversification by Descending Motor CircuitsControl of action diversification by descending motor circuits"], "Total_Cost": ["EUR 2 500 000"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["Descent"], "Technology_Description": "Movement is the behavioral output of the nervous system. Animals carry out an enormous repertoire of distinct actions, spanning from seemingly simple repetitive tasks like walking to much more complex movements such as forelimb manipulation tasks. An important question is how neuronal circuits are organized and function to choose, maintain, adjust and terminate these many distinct motor behaviors. Recent technological advances in neuroscience have made it possible to begin to unravel the links between the organization of specific neuronal circuit elements in the CNS and the control of movement, a topic that will be central to this research program.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2016-09-01"], "Project_ID": ["692617"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["NVISION IMAGING TECHNOLOGIES GMBH", "UNIVERSITAET ULM"], "EU_Contribution": ["EUR 96 462,30"], "Project_Title": ["Translating quantum sensing into cost-effective molecular imaging"], "Total_Cost": ["EUR 96 462,50"], "Country": ["Germany", "Germany"], "Project_ACR": ["QUSMI"], "Technology_Description": "The ability to recognize molecular processes using novel imaging techniques is of fundamental importance for medicine, biology and biochemistry in the 21st century. Non-invasive molecular imaging has gained widespread use in patient management of cancer, life-science and medical research, as well as drug discovery and development. The capability of non-invasive metabolic profiling is expected to impact dramatically patient management for socioeconomically relevant diseases. Spatially-resolved observation of metabolites will be key for enabling more accurate staging of diseases by direct assessment of the underlying impact on the metabolism. Quantification of, for example, the perturbation of the myocardial, tumor, or neural substrate metabolism will most likely revolutionize staging and management of diseases in cardiology, neurology, oncology and other fields. ", "To": ["2018-10-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-04-2016-2017 - FET Innovation Launchpad"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Germany"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["754346"], "Call_for_Proposal": ["H2020-FETOPEN-4-2016-2017"]}, -{"Partners": ["UNIVERSITY OF LIMERICK"], "EU_Contribution": ["EUR 1 840 800"], "Project_Title": ["Advanced Learning in Evolving Critical Systems"], "Total_Cost": ["EUR 3 681 600"], "Country": ["Ireland"], "Project_ACR": ["ALECS"], "Technology_Description": "Globally, software-based systems are increasingly important to economic activity and to the normal functioning of our everyday lives. The scope, scale and interconnected nature of such systems are increasing rapidly, with the potential consequences of failure, security breaches or malfunction becoming a growing cause of concern. Evolving Critical Systems (ECS) that change over time (\u201cevolving\u201d), and strategically important to their users (\u201ccritical\u201d), are increasingly prevalent in software development, from business-critical systems (e.g. airline websites) to safety-critical systems (e.g. automotive braking control system). ", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2016 - Co-funding of regional, national and international programmes"], "Funding_scheme": ["MSCA-COFUND-FP - Fellowship programmes"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["754489"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2016"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["A Place for the Asylum Seekers. European migration policies and their socio-spatial impacts"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["PASS"], "Technology_Description": "In the past two years the European Union has seen an enormous influx of migration. More than 1 million people arrived by boats in 2015 and more than 230,000 people in the first six months of 2016.", "To": ["2020-02-29, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["752021"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["MAGYAR TUDOMANYOS AKADEMIA CSILLAGASZATI ES FOLDTUDOMANYI KUTATOKOZPONT"], "EU_Contribution": ["EUR 146 239,20"], "Project_Title": ["The initial 244Pu abundance of the Solar System"], "Total_Cost": ["EUR 146 239,20"], "Country": ["Hungary"], "Project_ACR": ["IPUSS"], "Technology_Description": "The proposed project is a crossroad of noble gas cosmochemistry, geochemical modelling and astrophysics. We will obtain a best estimate of the initial 244 Plutonium content of the Solar System at the time when the first condensed mineral assemblages formed in the hot solar nebula. We will apply this value to model the volatile depletion history of the silicate Earth and to produce the first self-consistent estimate on the timing of the last addition of matter produced in rapid neutron capture processes (r process) to the Solar System. 244 Pu is an r-process- only short lived radionuclide that goes through spontaneous fission to produce Xenon isotopes and in principle the 244 Pu-Xe system can be used as chronometer to date early volatile loss events in Solar System solids. We propose a comprehensive experimental approach to study noble gases in combination with Nd (similarly volatile to Pu) and U (more volatile than Pu) abundances on a complementary set of samples that is adequate to explain the possible variation in the initial Pu/U ratio in different meteorites and early condensed mineral assemblages and to evaluate the applicability of the chronometer. While the Experienced Researcher is an expert in noble gas geochemistry and has experience in geochemical modelling, she will gain the knowledge on cosmochemistry and stellar nucleosynthesis required to interpret and discuss the new results produced in this project. The individual fellowship will help her start her early career as a postdoc and provide a crucial mobility to build a network in Europe and do research with high impact.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Hungary"], "Activity": ["Research Organisations"], "From": ["2017-10-01"], "Project_ID": ["753276"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["MEMory processing in the human ENTOrhinal cortex"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["MEMENTO"], "Technology_Description": "Deeply embedded in the medial temporal lobe (MTL) memory system, the entorhinal cortex (EC) is a small yet potentially key region for intact memory. While a series of recent ground-breaking findings in rodents point towards a pivotal role of EC in spatial navigation, thought of as an evolutionary precursor to memory, little is known about its precise contribution to episodic memory in humans. Building on preliminary evidence that EC subregions may be specialised for different stimulus types and/or different memory processes, MEMENTO proposes a systematic investigation of memory function in the human EC. The action combines state-of-the-art high-resolution and ultra-high field functional magnetic resonance imaging (fMRI) with advanced analysis techniques to assess how these EC subregions support material-specific memory processing on four levels of resolution: the laminar level, the subregion level, the system level, and the behavioural level. MEMENTO is highly collaborative: it brings together expertise of the ER (high-resolution fMRI of entorhinal cortex subregions), the host supervisor (functional dynamics of the MTL, advanced fMRI analysis), and the partner organisation (ultra-high field fMRI). Given that the EC is one of the first structures affected in Alzheimer\u2019s disease, the project results have great potential to stimulate important clinical implications. The ER will advance her research profile through highly transferable experience not only with cutting-edge methods, but also with managing and engaging in scientific and public communicative events. This will qualify her to lead her own research group upon returning.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["752557"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Modulation of Basket cell microcircuits in cerebellar cortex paroxysmal ataxia disorders"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["BaskAtax"], "Technology_Description": "The episodic ataxias are a group of hereditary conditions with recurring paroxysms of cerebellar dysfunction. They are rare; however they share important similarities to other more prevalent paroxysmal disorders such as migraine and epilepsy. The prototypic cerebellar cortex paroxysmal disorder is Episodic ataxia 1 (EA1), which is linked to dominantly inherited missense mutations in the Kv1.1 potassium channel subunit. Work from an animal model harbouring a human EA1 mutation reveals altered synaptic function at basket cell terminals in the cerebellar cortex. However how EA1 mutations affect basket cell regulation of Purkinje cell firing is unclear, possibly due to unforeseen changes in a specialized inhibitory structure called the pinceau. Furthermore the mechanism whereby local synaptic deficits extend to global cerebellar cortex network dysfunction during attacks of incoordination is unknown. This MSC research action aims to understand these processes using a combination of cutting edge in vitro and in vivo techniques. Using advanced electrophysiology techniques, I will assay basket cell pinceau function in mouse models of EA1, then using multi-photon and conventional microscopy I will map local basket cell microcircuits. Finally building on in vitro experiments I will assay candidate small molecule therapies in vivo, both with electrophysiology and with behavioural test of cerebellar coordination. The project allows me to train in state-of-the-art in vitro and in vivo methods while drawing on my extensive background in neuropharmacology, biochemistry electrophysiology. This research action will also advance our understanding of paroxysmal neurological disorders and identify new therapeutic targets.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["753796"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU"], "EU_Contribution": ["EUR 196 400,40"], "Project_Title": ["Effects of global change on the social behaviour of marine organisms"], "Total_Cost": ["EUR 196 400,40"], "Country": ["Norway"], "Project_ACR": ["GlobChangeBehav"], "Technology_Description": "The IPCC projects a 0.2-0.3 unit decrease in oceanic pH and a concurrent 1.0-3.7\u00b0C increase in sea surface temperature by 2100. These changes will have considerable impacts on marine organisms and are a threat to European and global biodiversity, food security, and socioeconomic productivity. While physiological impacts associated with marine global change have been well documented, behavioural impacts are less well known, even though behaviour has a major influence on the structure and function of marine communities. Furthermore, of the documented behavioural changes associated with global change, social behaviours - which play a key role in the survival and persistence of marine animals \u2013 are largely ignored. This project thus aims to advance current knowledge of global change biology by testing hypotheses pertaining to the impacts of ocean acidification and warming on the social behaviour of marine organisms spanning a wide range of taxa \u2013 from invertebrates to fish. Herein, it is hypothesized that predicted near-future (i.e., 2100) CO2 and temperature conditions will alter the social behaviour of crustaceans (shrimp shoaling), echinoderms (urchin and sea star aggregations), and fish (stickleback shoaling). This project will also test for physiological mechanisms underpinning global change-induced behavioural changes (GABAA functioning), as well as transgenerational effects (transgenerational acclimation in stickleback shoaling behaviour). The training, mentorship, and practical experience associated with this project will provide the fellow with the skills and competency to become an international leader in global change biology and marine animal behaviour. Furthermore, the knowledge generated by this project will answer critical questions in global change biology, which can be used by scientists, policy makers, stakeholders, and the general public, and will contribute to a much needed unifying theory of how global change will affect marine species.", "To": ["2020-03-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-04-01"], "Project_ID": ["752813"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["In vitro reconstitution and single cell analysis of the Shigella-septin cage."], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["INCAGE"], "Technology_Description": "Autophagy, an intracellular degradation process, is an important defence mechanism against pathogenic bacteria, including the Gram-negative enteroinvasive human pathogen Shigella flexneri. Work has shown that septins, a component of the cytoskeleton that interacts with membranes, entrap cytosolic Shigella in cage-like structures for targeting to autophagy. However, the factors mediating septin cage formation are mostly unknown. The Mostowy lab has recently discovered that mitochondria are required for efficient septin cage assembly and that ~50% of entrapped Shigella are metabolically inactive. The precise fate of septin cage-entrapped bacterium (replication, persistence, death) remains to be defined. For my project, called INCAGE, I will reconstitute the septin cage in vitro and study host and bacterial factors that modulate septin assembly. I will purify septin complexes and reconstitute septin assemblies (filaments, rings, cages) in vitro, and investigate how auxiliary components (actin, mitochondria, endoplasmic reticulum) influence septin cage assembly. This will reveal how septins recognize bacteria and how they assemble into cage-like structures. In parallel, I will follow septin cage-entrapped Shigella at the level of the single cell to study the lethal action of septin caging and uncover mechanisms that enable bacterial survival. I will test if the subpopulation of septin cage entrapped bacteria that stay alive, can replicate or led to the formation of persister cells (transiently refractory to stress) able to cope with host imposed stress (antibiotics, autophagy). Completion of these objectives will identify factors that promote septin cage assembly and its lethal action against entrapped bacteria. In depth understanding of septin cage assembly and its antibacterial activity can reveal important information about septin biology and cell-autonomous immunity, and help to design novel approaches to counteract bacterial infections.", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["752022"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["NATURAL HISTORY MUSEUM"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Phenotypic and lineage diversification of natricine snakes"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["NATRICINE"], "Technology_Description": "The NATRICINE project is a study of the macroevolution of a major group (240 extant species) of snakes. Natricines originated in Asia and dispersed into N America, Africa and Australasia. They are diverse, with repeatedly evolved surface, burrowing and aquatic ecotypes. The overarching project aim is to determine the extent to which lineage and phenotype diversification is impacted by dispersal to new regions (potentially providing ecological opportunity) and by evolutionary transitions between ecotypes. The overarching aim will be tackled via four main research objectives: molecular phylogenetics to determine the interrelationships among >70% of all natricine species; historical biogeography to identify ancestral areas and the location and timing of major dispersal events; phenotypic disparity and diversity analyses to quantify the main axes of natricine variation in time and space; quantitative analyses to test whether different ecotypes and geographical groups have undergone different rates of lineage and phenotype diversification. These four objectives will be tackled in four work packages. The topic is novel and the approach is innovative in combining cutting-edge techniques including amplification of DNA sequences from historical museum specimens, quantifying shape variation using the latest surface and microCT scanning approaches, and model-based analyses of trait and lineage evolutionary rate shifts. The project will be undertaken by an early-career postdoctoral researcher, who has expertise and solid grounding in Asian reptile systematics, ecology and evolution, but who requires training in advanced Next Generation Sequencing, 3D imaging and macroevolutionary quantitative analysis. The fellow will also receive training in public engagement, project management, student supervision and grant writing. This training will establish the fellow as a prominent vertebrate biologist who will lead European-Indian collaborative biodiversity research for years to come.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2017-09-01"], "Project_ID": ["751567"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU"], "EU_Contribution": ["EUR 196 400,40"], "Project_Title": ["INnovation through bIg daTa and socIal enTreprEneurship"], "Total_Cost": ["EUR 196 400,40"], "Country": ["Norway"], "Project_ACR": ["INITIATE"], "Technology_Description": "The power of big data and their applications is evident through the enormous attention they have received over the past few years, with the majority of the research focusing on solving technical and business problems. However, the challenge remains on how to harness the potential of big data in order to come up with innovative solutions on various societal problems. Big data has the potential to change the way entrepreneurs, as well as the other stakeholders of a social ecosystem, take decisions, and develop new paths to create social innovation (SI) by taking informed/data-driven decisions. Nonetheless, there is limited understanding on how social ecosystems need to change to embrace the advancement that big data entails. The purpose of INITIATE is to institutionalize INnovation through bIg daTa and socIal enTreprEneurship, and to examine how to successfully exploit big data towards achieving social good and sustainable change. INITIATE will build on the current state of the art, and go beyond it by merging and extending the findings with insights from the different stakeholders involved in the SI process (entrepreneurs, policy makers, social innovators). The project will be based on a rigorous research process consisting of systematic literature review and empirical investigations and it will develop and test a framework of best practices. Interested stakeholders will use the framework as a roadmap to successfully exploit big data for SI. INITIATE will offer practical and theoretical implications through the development of prototype applications which will clearly showcase the impact of big data on addressing societal challenges. Through INITIATE both the researcher and the host institution will benefit by the transfer of knowledge, and the researcher will develop his skills further and acquire new ones. The host will benefit by the researchers\u2019 developed knowledge, especially since this is consistent with the department\u2019s goals and strategic focus areas.", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["751510"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UMEA UNIVERSITET"], "EU_Contribution": ["EUR 185 857,20"], "Project_Title": ["Unveiling the mitochondrial role of DNA2, a human helicase-nuclease causing mtDNA deletion associated syndrome."], "Total_Cost": ["EUR 185 857,20"], "Country": ["Sweden"], "Project_ACR": ["MITOQUAD"], "Technology_Description": "Multiple deletions in mtDNA give rise to a variety of neuromuscular symptoms, often associated with genetic inherited disorders and aging and they have been reported in patients with neurodegenerative diseases, such as Parkinson\u2019s and Alzheimer\u2019s diseases. In spite of its medical importance, not much is yet known about the mechanisms by which mtDNA deletions are formed. Progressive external ophtalmoplegia (PEO) is one of the conditions characterized by the accumulation of mtDNA deletions. This disease is caused by mutations in components of the mtDNA replication machinery, like the DNA polymerase \u03b3 (POL\u03b3) and the replicative helicase TWINKLE. Recently, also the helicase-nuclease DNA2 has been found mutated in patients affected by this disorder. The precise function of human DNA2 (hDNA2) has remained elusive. hDNA2 localizes to mitochondria and has the biochemical properties to process four-stranded DNA structure (G-quadruplexes). Interestingly, G-quadruplex DNA associates with mtDNA deletions formation in human diseases. ", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["751474"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["The role of novel opsins in non-visual light detection in the zebrafish brain"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ZNEOPSIN_II"], "Technology_Description": "Light impacts on life by modulating the physiology and behaviour of most living organisms. Both vertebrates and invertebrates have developed an extensive and diverse range of photoreceptor structures and photopigments, which mediate these light responses. Clearly light is used for vision, being detected by specialized rod and cone cells in the retina and processed by the visual centers of the brain. However, light also regulates many non-visual processes, and novel nonvisual photopigments are regularly being discovered. Recent studies have shown a role for non-visual photoreception in seasonal responses, activation of DNA repair mechanisms, entrainment of the circadian clock and sleep-wake regulation, but the mechanisms are far less understood. This phenomenon is particularly extensive in teleosts such as zebrafish, where all tissues and cells of the adult and larval body are directly light responsive. The purpose of ZNEOPSIN_II is to determine the role that non-visual light detection plays in early development in zebrafish, focusing on neurobiology, the entrainment of the circadian clock and specific aspects of behaviour. I will take advantage of zebrafish, a genetic model organism available at the host lab, a leading zebrafish circadian biology lab at University College London, which is also one of the larger zebrafish research communities in Europe. The latest technical approaches for gene knockdown (CRISPR/Cas genome editing), and luminescent/fluorescent imaging, together with classical molecular biology techniques, will be combined with state of the art behavioural assays developed in zebrafish. The results of ZNEOPSIN_II will provide invaluable insights into the biological significance of non-visual light detection, and the roles played by a range of newly discovered opsins, as well as provide a junior researcher with the best possible training in both molecular biology, functional neurobiology and behaviour.", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["749990"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["The evolutionary history of oncogenic and non-oncogenic papillomaviruses"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["ONCOGENEVOL"], "Technology_Description": "Certain papillomaviruses (PVs) are a major public health concern as in humans they are responsible for virtually all cases of cervical and anal cancer, and for a fraction of cancers on the penis, vagina, vulva and oropharynx. But oncogenic PVs are actually an unfortunate exception, as most PVs cause asymptomatic infections, and a few cause benign, wart-like lesions. Despite the efforts directed towards the understanding of the different clinical manifestations of infection, our knowledge on PV evolution remains fragmentary.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2017-06-01"], "Project_ID": ["750180"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["TOSHIBA RESEARCH EUROPE LIMITED"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Development of an Ultra-Fast, Integrated, Certified Secure Quantum Random Number Generator for applications in Science and Information Technology"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["UFICS-QRNG"], "Technology_Description": "The objective of this SE action is the development of an innovative quantum random number generator (Q-RNG). This device will represent an important shift forward in the current panorama of physical RNG. In fact, it will meet simultaneously three requirements: being Ultra-Fast, Integrated, Certified Secure. The UFICS-QRNG will be developed with an SE action that will last 24 months. The researcher, that has matured a relevant expertise in the field of QRNGs, will join the Quantum Information Group at the Toshiba Research Laboratories (TREL) based in Cambridge, UK. These laboratories are worldwide known for cutting edge research in Quantum Optics and Quantum Information. The project starting point will be a fast QRNG prototype, recently developed by TREL. During the action, the researcher will develop a theoretical model to certify the randomness of the generator and will implement an integrated hardware. The UFICS-QRNG will be characterized by an unprecedented level of security. Besides the theoretical model, which will account for all the side information sources that might weaken the generator unpredictability, the device will feature a self-testing protocol, for the continuous monitoring of the entropy. The hardware will be designed to be compatible with other systems and the compliant with the standards. Security, generation rate at Gigabit/s and the possibility of integration in servers and computers, will make the UFICS-QRNG suitable for a variety of applications in Science and Information Technology, which range from experiments of fundamental physics to simulation and cryptographic applications. In the latter case, the UFICS-QRNG will represent the best answer to the lack of physical RNGs able to substitute the unsecure pseudo-RNGs. Given the peculiarity of TREL, an industrial institution that produces high impact scientific works, the researcher will benefit of a unique training, with the possibility to develop a professional profile at the highest levels.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-SE - Society and Enterprise panel"], "Coordinated_in": ["United Kingdom"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-04-01"], "Project_ID": ["750602"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["PANEPISTIMIO KRITIS"], "EU_Contribution": ["EUR 152 653,20"], "Project_Title": ["Florinated MOF for toxic gas capture"], "Total_Cost": ["EUR 152 653,20"], "Country": ["Greece"], "Project_ACR": ["FluMToGaC"], "Technology_Description": "Air pollution is both, an environmental and a social problem as it affects human health, ecosystems and play a key role in global warming. More than 80% of people are exposed to air quality levels that exceed safe limits, being responsible for many premature deaths. European commission estimated to several billion euros the health-related cost due to air pollution. Some of the most important molecules accused by Europe, and so need to be reduce from atmosphere, are nitrogen oxides, sulphure oxide, hydrogen sulfide and ammonia. In order to capture them from air, a convenient method is to use porous materials. Metal-Organic-Framework, a relatively new class of porous material, built up from polytopic linker and inorganic node or clusters, already demonstrated excellent performance for gas capture. The tunability, at molecular level of these materials makes them serious candidates for separation applications. Recently, the applicant was part of the team who designed a fluorinated MOF with a suitable pore and aperture size for selectively capturing propylene from propane , or capture CO2 from air at ppm level. This very robust material is opening the path of fluorinated hybrid material for toxic gas separation and capture. This project aim to design, synthesis and characterize new single and mixed metal fluorinated MOFs in order to evaluated their capabilities for harmful gas capture.", "To": ["2020-01-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Greece"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-15"], "Project_ID": ["750533"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF SUNDERLAND"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Lean data management for maintenance value"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["LeaD4Value"], "Technology_Description": "The possibilities of data-based maintenance management as well as interconnected, smart, and autonomous assets have been discussed lately but in practice there are still a number of major problems regarding e.g. the amount, quality, integration, and exploitation of maintenance data. In LeaD4Value these problems are addressed through lean maintenance data management to realise increased business value. Contrary to the Big Data hype, the idea here is to focus on the data decision support tools to be constructed based on analytical modelling and statistical analyses. Data will be collected from computerized maintenance management systems and enterprise resource planning systems of the two seconded companies, as well as from some of their employees via surveys and interviews. The results include e.g. a map of data exploitation paths, a process model, and a performance measurement system for lean maintenance data management. These tools can be used to reveal unnecessary maintenance tasks and data collection, missing data collection, or potential to increase the business value of maintenance. The role of world-class maintenance is highlighted in European manufacturing, because a majority of new production-related investments are directed to other continents. The proposed work is multidisciplinary by nature, combining aspects of business value management, reliability and maintenance engineering, and data sciences. The multidisciplinary view is needed, for asset management is challenged by maintenance engineers and managers understanding the technical aspects of maintenance but being unable to communicate these to the company decision makers in terms of business value. Too often this leads to short-sighted decisions. The project will expand the competences of the fellow in multiple disciplines, and provides international experience in science and business.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["751622"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["EUROPEAN MOLECULAR BIOLOGY LABORATORY"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Luminal pressure: a sculptor for mouse blastocyst self-organisation"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["Fluidblasto"], "Technology_Description": "An important morphogenetic event of mammalian embryogenesis is the formation of a blastocyst with a fluid-filled cavity, blastocoel, and the establishment of three cell types essential for implantation. Morphogenesis of the blastocyst begins with the emergence of multiple nascent cavities, which progressively coalesce to form one cavity segregating the cavity-facing primitive endoderm from the epiblast within the inner cell mass. While cell-to-cell gene expression heterogeneity is well characterised during this lineage specification, little is known about the physical principles governing self-organized blastocyst morphogenesis and patterning. In particular, changes in fluid pressure, cell shape and polarity during blastocyst formation remain uncharacterized. In this project, I will study the roles of fluid cavities in coordinating tissue mechanics, polarity and lineage specification. I will establish a novel micropressure technique to quantify the growth of luminal pressure during blastocyst development. Combining micropipette aspiration with high-resolution live-embryo imaging, I will characterize the impact of fluid pressure on trophectoderm fate specification through dynamic changes in cell shape and adhesion, and cytoskeletal remodeling. To assess the impact of fluid pressure on inner cell mass, I will study if cavity expansion induces apical polarisation and enhances primitive endoderm differentiation in cavity-facing cells. Combining laser ablation with light-sheet microscopy, we will build a spatio-temporal map of intercellular forces in vivo during blastocyst development. We will further manipulate the cavity size to study if fluid pressure is functionally required and sufficient for driving lineage segregation. This interdisciplinary and quantitative study will establish the novel role of fluid cavities and elucidate their interplay with biochemical signaling within the multi-cellular self-organization process.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-09-01"], "Project_ID": ["748752"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Exploring Gender in Children's Literature from Cognitive Corpus Stylistic Perspective"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["GLARE"], "Technology_Description": "Gender equality remains a critical societal challenge. But how does one \u2018learn\u2019 gender? Children\u2019s literature presents one early source of cultural norms, values and assumptions about gender. Language use in these texts is a crucial means by which children learn about gendered concepts and behaviours. To understand this formative influence more deeply, the innovative GLARE project will examine the discursive construction of gender in corpora of English children\u2019s literature drawing on a novel cognitive corpus stylistic approach to characterization to conceptualise the notion of gender. GLARE will further take a diachronic perspective to the development of gender representation over time. The \u2018cognitive corpus stylistics\u2019 links together corpus linguistics (CL) and Cognitive Poetics (CP). CL methods combine qualitative and quantitative approaches to text analysis while CP offers a theoretical framework to account for the creation of meaning in the mind of the reader. The approach adopted by GLARE stresses that the representation of real and fictional people is related \u2013 in terms of the background knowledge that readers bring to texts and in terms of the patterns used in a text. Hence, relationships between the representation of fictional characters and real people are to some extent a reflection of links between patterns in fictional and non-fictional texts. To investigate this relationship, the project draws on complementary data from the Times Digital Archive. Through the description and analysis of linguistic patterns GLARE will provide novel insights into the way in which children\u2019s literature can influence the creation of gendered concepts and behaviours. GLARE will be situated at the University of Birmingham and supervised by Prof. Michaela Mahlberg, a world-leading expert in corpus stylistics. A secondment at Oxford University Press will allow the unique opportunity to access the largest electronic collection of children\u2019s books, the Oxford Children\u2019s Corpus.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["749521"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE PARIS DESCARTES"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["HEpatocellular carcinoma GErmline MutatiONs ImpaCt (HEGEMONIC)"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["HEGEMONIC"], "Technology_Description": "Hepatocellular carcinoma (HCC) is the second most common cause of cancer death worldwide. Although several environmental factors have been identified, many affected individuals never develop HCC, suggesting a genetic susceptibility. Candidate genes and genome-wide association studies (GWAS) have only uncovered a few variants reproducibly linked to HCC. GWAS design typically allows the detection of common variants that usually have small effect sizes. Even taken together, they explain a very limited proportion of the heritability. This could reflect the presence of rare variants that may confer very large effect sizes. These may be captured by next-generation sequencing (NGS). Whole exome sequencing (WES) of thousands of tumors has defined the somatic genetic landscape of the most common cancers. Using WES, the host group has strongly contributed to the identification of the major pathways recurrently mutated in HCC. Nevertheless, despite the large amount of NGS data generated by cancer genome projects, the analysis of rare germline variants (i.e. variation pre-existing in normal cells) is currently a neglected field, particularly in liver carcinogenesis. The HEGEMONIC project hypothesizes that rare variants in coding regions of the genome (exome) impact the risk of HCC. This project proposes an integrative approach combining (epi)genomic information generated by the host group and from publicly available sources. First, the applicant will compare WES data from a series of 350 patients with HCC to nearly 70,000 controls compiled by the Exome Aggregation and UK10K consortia. Then, validation of the top signals will be performed by conventional sequencing in three replication cohorts. Finally, the applicant will analyze genotype-phenotype associations, taking advantage of the extensive clinical data available. Ultimately, the HEGEMONIC project may generate new biological hypotheses in liver carcinogenesis and identify new biomarkers and pharmaceutical targets.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["748604"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["TALLINNA TEHNIKAULIKOOL", "BRANDENBURGISCHE TECHNISCHE UNIVERSITAT COTTBUS-SENFTENBERG", "TECHNISCHE UNIVERSITEIT DELFT", "POLITECNICO DI TORINO", "CADENCE DESIGN SYSTEMS GMBH", "IROC TECHNOLOGIES SA", "INTRINSIC ID B.V.", "IHP GMBH - INNOVATIONS FOR HIGH PERFORMANCE MICROELECTRONICS/LEIBNIZ-INSTITUT FUER INNOVATIVE MIKROELEKTRONIK"], "EU_Contribution": ["EUR 3 755 824,92"], "Project_Title": ["Interdependent Challenges of Reliability, Security and Quality in Nanoelectronic Systems Design"], "Total_Cost": ["EUR 3 755 824,92"], "Country": ["Estonia", "Germany", "Netherlands", "Italy", "Germany", "France", "Netherlands", "Germany"], "Project_ACR": ["RESCUE"], "Technology_Description": "RESCUE ITN advances scientific competences and establishes an innovative training for Interdependent Challenges of Reliability, Security and Quality in Nanoelectronic Systems Design.", "To": ["2021-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Estonia"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations"], "From": ["2017-04-01"], "Project_ID": ["722325"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["EUROPEAN MOLECULAR BIOLOGY LABORATORY"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["In Situ structural Analysis of Nuclear Pore Complex ASsembly Intermediates by cryo-FIB-tomography"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["ISA-NPC-ASI"], "Technology_Description": "Nuclear pore complexes (NPCs) are fundamental supra-molecular complexes mediating the molecular traffic between nucleus and cytoplasm. They consist of over 1000 proteins that need to be assembled in a coordinated manner each cell division. Recent structural work has elucidated a considerable part of the NPC architecture, however how the NPC scaffold is assembled remains poorly understood on the structural and mechanistic level. ", "To": ["2020-08-31, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-09-01"], "Project_ID": ["745988"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["VRIJE UNIVERSITEIT BRUSSEL"], "EU_Contribution": ["EUR 172 800"], "Project_Title": ["How should automated profiling be regulated?"], "Total_Cost": ["EUR 172 800"], "Country": ["Belgium"], "Project_ACR": ["PROFILE"], "Technology_Description": "Profiling may threaten values that the law aims to protect, and undermine goals that the law aims to achieve. Profiling involves automated processing of personal or other data to develop profiles that can be used to make decisions about people. Profiling can be used in different contexts. For instance, (i) with retail price discrimination, online shops charge different consumers different prices for the same or similar products. (ii) Lenders use profiling to estimate a consumer\u2019s creditworthiness. Lenders can adapt interest rates to certain consumers, or refuse to lend to them. (iii) Predictive policing refers to the use of profiling technology to predict criminal behaviour.However, profiling has drawbacks. For instance, profiling can discriminate unintentionally, when an algorithm learns from data reflecting biased human decisions. Additionally, profiling is opaque: people may not know why they are treated differently. Making profiling transparent is difficult, among other reasons because of the complexity and the possibly ever-changing nature of algorithms. ", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["748514"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FUNDACAO D. ANNA SOMMER CHAMPALIMAUD E DR. CARLOS MONTEZ CHAMPALIMAUD"], "EU_Contribution": ["EUR 148 635,60"], "Project_Title": ["Impact of Neuromedin U in type 2 immunity and mucosal defence"], "Total_Cost": ["EUR 148 635,60"], "Country": ["Portugal"], "Project_ACR": ["INIMUD"], "Technology_Description": "Group 2 innate lymphoid cells (ILC2) are critical players in mucosal defense, tissue homeostasis and inflammation. ILC2 development and function have been widely perceived to be programmed. Nevertheless, how ILC2 perceive, integrate and respond to environmental cues remains mostly unexplored. Here we hypothesize that ILC2 sense their environment and exert their function as part of a novel neuronal-ILC2 unit orchestrated by neuromedin U (NmU) signaling.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Portugal"], "Activity": ["Research Organisations"], "From": ["2017-07-01"], "Project_ID": ["750030"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Exploring the cellular heterogeneity underlying 'tumor-educated' platelets"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["PlateletLiquidBiopsy"], "Technology_Description": "Cancer is one of the major causes of death worldwide. Early detection leads to treatment initiation in earlier cancer stages and therefore increases the chance of survival. However, appropriate diagnosis can be challenging because tissue acquisition of tumor samples for molecular testing often requires invasive procedure. To overcome these challenges researchers have focused on the real-time monitoring of molecules and cells in easily obtainable peripheral blood to gain diagnostic information, termed 'liquid biopsies'. A recent study by Best et al profiled purified platelet gene expression from cancer patients and healthy controls and was able to predict disease status and location of the primary tumor with 96% and 71% accuracy, respectively using a machine learning based algorithm. The pan-cancer nature of their finding is a major advancement compared to other liquid biopsy approaches and highlights the utility of platelets as an all-in-one platform for blood-based cancer diagnostics. We plan to advance the idea of platelet liquid biopsies by studying platelet single-cell RNA sequencing data from cancer patients and healthy controls. The overall goal of the proposed project is to investigate single platelet gene expression to gain insight into the molecular mechanisms underlying tumor driven changes in the platelet RNA profile.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations"], "From": ["2017-07-01"], "Project_ID": ["753039"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ROYAL COLLEGE OF SURGEONS IN IRELAND"], "EU_Contribution": ["EUR 175 866"], "Project_Title": ["The ATP-P2X7R axis: a target for drug-refractory epilepsy"], "Total_Cost": ["EUR 175 866"], "Country": ["Ireland"], "Project_ACR": ["EpiPur"], "Technology_Description": "Current epilepsy therapies, based on mediating excitation or inhibition have no impact on disease progression and are ineffective in over 30% of patients, demonstrating the urgent need for therapies with different mechanisms of action. An exciting concept is that increased hyperexcitability states and network changes are caused and maintained by a sustained glial activation.The ATP-gated P2X7 receptor (P2X7R), a gatekeeper of inflammation, has recently emerged as a promising target for epilepsy, showing anticonvulsant and disease-modifying properties in animal models. To bring P2X7R further towards a clinical application, however, important gaps in our understanding must be filled. Evidence for ATP release in the brain during seizures is currently lacking, the cell types involved in pathological P2X7R activation must be determined, and whether results from rodent models can be replicated in human tissue must be tested. Recent technical advances now bring the answers to these questions within reach. EpiPur brings together a team of experts in purinergic signalling, industrial partners specialised in the development of P2X7R antagonists and epilepsy clinicians. Biosensors will be used to record ATP in vivo with high sensitivity and temporal resolution; new transgenic mouse lines will be used to elucidate the subcellular expression and cell-specific disease contribution of P2X7R. Newly developed P2X7R antagonists will be tested in brain tissue resected from epilepsy patients. This highly interdisciplinary and intersectoral approach will add a significant contribution to the understanding of neuroinflammatory processes in disorders of the CNS. Further, the skills acquired during the research project, the excellent training record of the supervisor and host institution and the outstanding resources for learning and development available at RCSI will give me the tools necessary to achieve research independence.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["753527"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Multi-level Model Calibration for the Assessment of Historical Masonry Structures"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["MultiCAMS"], "Technology_Description": "The MultiCAMS project will develop an advanced computational strategy including numerical modelling and innovative model calibration for realistic assessment of historical unreinforced masonry structures. The presence of relevant historical heritage in Europe, partly still in use, together with high seismic risk in the Mediterranean areas highlights the need of assessing such structures considering current safety requirements and if necessary strengthened to prevent critical failure. The proposed assessment approach is based on the use of models with different levels of sophistication, comprising detailed mesoscale models where masonry units and mortar joints are modelled separately (low level), homogeneous shell/solid-element models in which masonry is considered as a continuum (intermediate level), and efficient macroscale models where entire structural parts (i.e. piers, spandrels) are represented by appropriate macro-elements (high level). In this respect, I will develop a novel numerical description with macro-elements for an efficient and practical analysis of masonry structures accounting for the interaction between the nonlinear in-plane and out-of-plane behaviour of different URM components. An innovative model calibration strategy utilising inverse analysis techniques will thus be developed to couple the efficiency of the novel simplified mechanical model and the accuracy of existing detailed models, such as the parameters of each model will be determined from the inverse analysis of the numerical response of the lower-level model. The main outcome of MultiCAMS will be a comprehensive and accurate methodology for the seismic assessment of historical masonry buildings, which represents an urgent requirement for the safeguard of human lives in many European urban areas, as shown by recent catastrophic events.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["744400"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FUNDACIO INSTITUT CATALA DE NANOCIENCIA I NANOTECNOLOGIA"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["FLEXOELECTRIC SCAFFOLDS FOR BONE TISSUE ENGINEERING"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["FLEXOBONEGRAFT"], "Technology_Description": "\"Bone is the most transplanted tissue with 1.3 million procedures every year in Europe. With an increasing demographic ageing across Europe, bone transplant represents a significant socio-economic burden that necessitates new bone regeneration strategies in line with one of the Horizon 2020 priority: \"\"Smart Growth: knowledge and innovation based economy\"\". The field of bone tissue engineering has flourished over the last decades, owing to a solid knowledge on bone biology and increased progress on materials engineering. A few weeks ago, Dr Gustau Catalan at ICN2 brought to light the groundbreaking discovery that bone is flexoelectric. In order to biomimic the flexoelectric character of bone, we aim in this project to produce new synthetic bone scaffolds that exhibit flexoelectricity. Engineering scaffolds with a flexoelectric character calls for particular design requirements. Flexoelectricity is the coupling between strain gradients and polarization, whereby any dielectric can polarize in response to an inhomogeneous deformation. In order to generate the required strain gradients within the scaffold to produce a flexoelectric effect, scaffolds will be manufactured with controlled porosity gradients by 3D printing based approaches. Three polymers used in bone tissue engineering, namely PLLA, PLGA and PCL will be investigated to produce the flexoelectric scaffolds. It is envisaged that a flexoelectric-induced polarization can be attained in any of them. In view of improving the osteoconductive, osteogenic and mechanical properties of the flexoelectric scaffolds, they will further incorporate different amounts of nanohydroxyapatite (from 0 to 50 wt %). Finite element calculations will be used to refine porosity geometries (porosity gradient and pore shape). It is expected that through careful geometrical design of porosity, scaffolds could exhibit a bone-like flexoelectric effect that would not only support the bone tissue regeneration process but also stimulate it.\"", "To": ["2019-09-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-09-15"], "Project_ID": ["753186"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ITA-SUOMEN YLIOPISTO"], "EU_Contribution": ["EUR 1 255 680"], "Project_Title": ["Genomics and Mechanisms in Translational Medicine Doctoral Programme"], "Total_Cost": ["EUR 2 511 360"], "Country": ["Finland"], "Project_ACR": ["GenomMed"], "Technology_Description": "The GenomMed programme will train international experts who are wanted in the European job market and future research leaders in translational genomics. These experts aim to solve health care -related questions in cardiovascular and metabolic diseases and neurosciences. They will have skills to create solutions and innovations to develop novel treatments in the European and global environment. Health care is globally faced with a growing burden of major age-associated diseases. New means of diagnosis and treatment are needed to survive the challenges.", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2016 - Co-funding of regional, national and international programmes"], "Funding_scheme": ["MSCA-COFUND-DP - Doctoral programmes"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["740264"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2016"]}, -{"Partners": ["JOHANNES GUTENBERG-UNIVERSITAT MAINZ"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Fast electronics with Antiferromagnetic SpinTronics"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["FAST"], "Technology_Description": "The end of scaling according to Moore\u2019s law will reinforce the need to look for energy efficient and faster devices based on alternative materials and concepts that are however compatible with Complementary metal-oxide-semiconductor (CMOS). A new generation of logic and storage devices might arise from promising antiferromagnetic materials because of the absence of a net magnetic moment and of the characteristic frequencies of THz-order. In an antiferromagnet, the electron spins on adjacent atoms cancel each other out. An antiferromagnet has thus no associated magnetic field meaning that individual devices can encode information and be packed ultimately densely without interacting with one another. Simultaneously, the origin of this stability makes the antiferromagnet state difficult to read and control. The recent combination of antiferromagnets and spintronics has however opened the road towards the electrical control of their magnetic order. ", "To": ["2019-07-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-15"], "Project_ID": ["752195"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["A neuroscience approach to investigating how hierarchy influences moral behaviour"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["AGENT"], "Technology_Description": "Humans are very social animals who are able to understand the consequences of their actions on others. Therefore, why is it that some individuals are more likely to choose actions that have negative consequences for others? This project will explore this important question by using an original and innovative approach focusing on the subjective experience of agency and responsibility of individuals when they select a moral or an immoral action, together with their empathic response at the moment of the act. The general aim of the present research project is to refine our understanding of the mechanisms driving both responsibility and empathy and to generate a model that integrates these two aspects to better understand what guides moral behaviours in coercive situations. To achieve this aim, we will use psychophysiology and fMRI techniques to understand how the neural circuits associated with the sense of agency and empathy interact through different experimental paradigms. This project will shed new light on how our self-experience impacts on our moral decisions. In addition to opening new perspectives in social neuroscience and psychology, this project will add theoretical and methodological expertise to my skill-set by providing the most suitable environment, that is, the Social Brain Lab at the Netherlands Institute for Neuroscience (NIN), for my career development. The NIN will offer: (i) world experts in human empathy with prominent expertise in fMRI and EEG techniques (C. Keysers and V. Gazzola); (ii) all the technical facilities necessary for the success of the present research project, and (iii) a world leading neuroscience community that will contribute to my further training and career prospects.", "To": ["2019-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Research Organisations"], "From": ["2017-12-01"], "Project_ID": ["743685"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["The neural correlates of the self in altered states of consciousness."], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["NeuCoSe"], "Technology_Description": "The consciousness of self is fundamental to our human existence. In several mental health afflictions there appears to be a change in the relation between the self and conscious experience: in anxiety and depression, people can be absorbed in negative thoughts, while in (traumatic) dissociation, distance between the self and conscious experience can occur. Studies report that meditation and hypnosis can help alleviate symptoms of anxiety, depression and post-traumatic stress, but it is unclear why. I hypothesise that meditation and hypnosis change the relation between the self and the conscious experience. I aim to study the neural correlates of these changes in self-consciousness during meditative and hypnotic states with functional Magnetic Resonance Imaging in healthy controls and intracranial electroencephalography in people with epilepsy, which is the only way to directly measure the activity of deep brain structures thought to play a role in self-consciousness, such as the insula. I will combine these measurements with first-person interviews and behavioural tasks. This innovative study will elucidate the neural correlates of the consciousness of self and will help understand the reported beneficial effects of meditation and hypnosis on mental health.", "To": ["2019-06-20, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2017-06-21"], "Project_ID": ["749582"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION"], "EU_Contribution": ["EUR 187 419,60"], "Project_Title": ["The trade-off between longevity and reproduction: optimal control of aging"], "Total_Cost": ["EUR 187 419,60"], "Country": ["Switzerland"], "Project_ACR": ["OPTiAGE"], "Technology_Description": "The lifespan of genetically identical organisms varies depending on the environment they are exposed to. A well-known example is the extension of lifespan by nutrient restriction, as observed in animals as diverse as nematodes and rhesus monkeys. Why does the lifespan of animals change with environmental conditions? Is there an advantage to living longer when food is poor, and to living shorter when food is plentiful?", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Research Organisations"], "From": ["2018-09-01"], "Project_ID": ["751878"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAET LEIPZIG"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Perception of Eastern Religions in Europe"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["GINGER"], "Technology_Description": "The issues of globalisation, intercultural relations, migration crisis and ecological crisis are among the most challenging problems that Europe is currently facing. In their core lies the issue of identity-otherness dual. The present project attempts to address these problems in an innovative way seeking to understand whether the current situation in Europe leads to transformation of the dominant European worldview and whether and how Eastern religions influence this process. Therefore, the aim of the project is to investigate the contemporary interrelation between Europe and Eastern religions.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["753561"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KING'S COLLEGE LONDON"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Functional impact of alternative splicing coupled to nonsense-mediated decay in developing neurons"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["NEURO_NMD"], "Technology_Description": "Differentiation of precursor cells into mature neurons relies on transcriptome-wide changes in gene expression that have to be coordinated in a precise spatiotemporal fashion. Alternative pre-mRNA splicing coupled to nonsense-mediated decay (AS-NMD) is a widespread post-transcriptional mechanism known to orchestrate gene expression dynamics in developmental contexts. Earlier studies identified several neural targets of this pathway; however, in most cases, the extent to which AS-NMD contributes to the overall gene expression dynamics and biological significance of this regulation is poorly understood. Moreover, whether AS-NMD target repertoire undergoes considerable changes in developing brain and how this might fit to the global regulation network underlying neuronal differentiation remains unclear. I will address these questions using two separate approaches. First, I will investigate novel AS-NMD targets encoding actin cytoskeleton factors and controlled by an important regulator of neuronal alternative splicing, Ptbp1. I will elucidate the extent of AS-NMD regulation in these genes by modulating the inclusion of the NMD-promoting exons with corresponding antisense oligonucleotides. in mouse embryonic stem cells undergoing neuronal differentiation, neural stem cells and primary neurons. Second, I will systematically analyse how NMD contributes to different stages of neuronal development by acutely inhibiting this pathway in a time-resolved manner using genetic means. I will then identify gene expression effects and functional consequences of NMD inactivation using transcriptome sequencing (RNA-Seq) and appropriate cell biological methods. All in all, this work will provide critical quantitative insights into AS-NMD functions and uncover novel mechanisms allowing neurons to attain their unique morphological and functional properties.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["751739"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Investigating the structural role of the Hepatitis B virus core proteinC-terminal domain in assembly and maturation using solid-stateNMR"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["HBVssNMR"], "Technology_Description": "We will seek in this project to reveal structural and dynamic features of the C-terminal domain (CTD) of the Hepatitis B virus (HBV) core protein which encapsidates the viral genome. Each year, over 750,000 deaths are due to serious liver diseases caused by chronic HBV infection. Hepatitis B is, despite the availability of a vaccine, still a major health problem. The HBV virus particle is composed of an outer lipid-protein envelope and a core protein of 20 kDa that self-assembles into icosahedral nucleocapsids. The nucleocapsid encloses the pregenomic RNA (pgRNA) that is then reverse-transcribed into DNA by the viral polymerase (Pol). During pgRNA encapsidation, the CTD is thought to interact with the RNA. Despite the essential role played by the CTD in the regulation of the viral life cycle through various conformational states and phosphorylation patterns, it escapes today to classical structural biology approaches due to its dynamic nature. We will use solid-state NMR to bring new insights into the precise conformation and localization of the CTD along various steps of the viral life cycle. Sample preparation protocols of the core protein have recently been established by the applicant in the host laboratory using bacterial expression systems. The first NMR spectra of the nucleocapsid look highly promising. Further experiments will be recorded to assign the resonances and identify the CTD signals. Different phosphorylation states and binding partners, as the pgRNA, will be explored. Finally, paramagnetic tags will be used to obtain information about the positioning of the CTD. ", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2017-06-01"], "Project_ID": ["748516"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CARDIFF UNIVERSITY"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Innovation in Investigative Journalism"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SCOOP"], "Technology_Description": "The objective of SCOOP is to study the impact of innovative technologies and new funding mechanisms on the role and working practices on investigative journalism. Investigative journalism should play a key role in democracy, but developments in digital media and new technologies (drones, mobile cameras) and changing funding models (crowd sourcing) is transforming this.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["746899"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION"], "EU_Contribution": ["EUR 187 419,60"], "Project_Title": ["Muscle Specific C. elegans Genome in health and disease: finding novel factors in 3D organization"], "Total_Cost": ["EUR 187 419,60"], "Country": ["Switzerland"], "Project_ACR": ["MuSCel Genome"], "Technology_Description": "The loss of structural integrity in the interphase nucleus leads to tissue-specific pathologies in a set of human diseases collectively called laminopathies. These are late-onset, tissue-specific degenerative diseases, such as Emery Dreifuss Muscular Dystrophy (EDMD). While rare, these conditions provide insight into more common degenerative disorders linked to aging. A Caennorhabditis elegans mutant that recreates the EDMD phenotypes arises from introduction of a specific gain-of-function mutation into lamin (LMN-1 Y59C), which in turn affects the subnuclear distribution of muscle-specific promoters. This proposal plans to identify novel factors that establish and/or maintain the 3D organization of the genome in differentiated nuclei and to determine how this contributes to the differentiated muscle cell fate. I propose that compromised or altered sequestration of chromatin at the nuclear envelope alters cell-type specific promoter induction and in turn compromises the integrity of the tissue in question. ", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Research Organisations"], "From": ["2017-04-01"], "Project_ID": ["750114"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY"], "EU_Contribution": ["EUR 170 509,20"], "Project_Title": ["New Material Hybrids With Helical Inner Architecture: Fundamentals And Technology"], "Total_Cost": ["EUR 170 509,20"], "Country": ["Israel"], "Project_ACR": ["HybridMat"], "Technology_Description": "A new approach to design and manufacture hybrid materials based on biomimetic principles is proposed. The internal structure of multi-component metal hybrids will be created simultaneously at two levels: nanostructuring each constituent while also architecturing helical macroscale features. ", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["742098"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["RIJKSUNIVERSITEIT GRONINGEN"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["Microscopic modelling of the highly efficient intra- and inter-antennae energy transfer to the reaction centre in plant photosystem II"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["MicroMod-PSII"], "Technology_Description": "MicroMod-PSII aims to provide an unprecedented microscopic, structure-based understanding of the excitation energy transfer mechanism in plant photosystem II (PSII) from the outer antennae complexes to the reaction centre under physiological conditions. It will unravel nature\u2019s highly sophisticated way of harvesting sunlight in unrivalled detail.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["748895"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION"], "EU_Contribution": ["EUR 175 419,60"], "Project_Title": ["Understanding long-range transcriptional regulation in the context of the 3D genome organization"], "Total_Cost": ["EUR 175 419,60"], "Country": ["Switzerland"], "Project_ACR": ["3DQuant"], "Technology_Description": "Enhancers are regulatory elements that control the spatial and temporal expression of genes in metazoans. Enhancers are able to modulate transcription of a target gene from large genomic distances, as a result of the formation of chromatin loops that bring them in close spatial proximity to cognate promoters. The manner how specific patterns of enhancer-promoter physical interactions are established is linked to how chromosomes are folded in the three-dimensional (3D) space. Recent studies based on chromosome conformation capture (3C) have shown that mammalian chromosomes are partitioned into self-associating sub-megabase domains called Topologically Associating Domains (TADs). Genetic evidence suggests that 3D chromatin organization within and across TADs contributes to the establishment and partitioning of enhancers-promoters physical communication. Yet it is still unknown by which biophysical mechanisms chromosome architecture modulates enhancer action, and thus transcription. The goal of this proposal is to determine the quantitative relationship between 3D chromatin architecture and enhancer-promoter activity to unravel the mechanism of long-range transcriptional modulation mediated by enhancers. Addressing this goal requires a system where transcriptional outputs can be measured precisely and quantitatively, and correlated with 3D distances. To this aim, we will use state-of-the art genome engineering techniques to generate mouse embryonic stem cells with engineered enhancer-promoter pairs in an isolated chromatin environment, where a selected enhancer can be mobilized at different distances from its cognate promoter. We will use this system to quantitatively assess how 3D chromatin structure influences enhancer action by measuring transcription and promoter-enhancer interactions using 3C-based technologies, single-cell methods and live-cell imaging. This will lead to an unprecedented view of the mechanisms underlying long-range transcriptional regulation.", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Research Organisations"], "From": ["2017-03-01"], "Project_ID": ["748091"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE LIBRE DE BRUXELLES"], "EU_Contribution": ["EUR 172 800"], "Project_Title": ["Brain-speech tracking in noisy conditions: towards the identification and remediation of dyslexia."], "Total_Cost": ["EUR 172 800"], "Country": ["Belgium"], "Project_ACR": ["DysTrack"], "Technology_Description": "Dyslexia is a developmental disorder leading to reading difficulties. It affects 5\u201312 % of children and young adults. Unfortunately, we still lack efficient and cost effective methods to identify and remedy this disorder. Dyslexia appears to be frequently linked to hindered phonological processing at the cortical level, with drastic consequences in the presence of noise. The overarching goal of this project is to better understand cortical speech processing in the presence of noise, in order to provide novel identification and remediation methods for dyslexia.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["743562"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS", "UNIVERSITY OF CYPRUS", "FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.", "SIGNALGENERIX LTD", "UNIVERSITAT POLITECNICA DE CATALUNYA", "AALTO-KORKEAKOULUSAATIO"], "EU_Contribution": ["EUR 5 748 000"], "Project_Title": ["VisorSurf - A Hardware Platform for Software-driven Functional Metasurfaces"], "Total_Cost": ["EUR 5 748 000"], "Country": ["Greece", "Cyprus", "Germany", "Cyprus", "Spain", "Finland"], "Project_ACR": ["VISORSURF"], "Technology_Description": "Metasurfaces, thin film planar, artificial structures, have recently enabled the realization of novel electromagnetic (EM) and optical components with engineered functionalities. These include total EM radiation absorption, filtering and steering of light and sound, as well as nano-antennas for sensors and implantable devices. Nonetheless, metasurfaces are presently non-adaptive and non-reusable, restricting their applicability to a single, static functionality per structure (e.g., steering light towards a fixed direction). Moreover, designing a metasurface remains a task for specialized researchers, limiting their accessibility from the broad engineering field. VISORSURF proposes a hardware platform-the HyperSurface-that can host metasurface functionalities described in software. The HyperSurface essentially merges existing metasurfaces with nanonetworks, acting as a reconfigurable metasurface whose properties can be changed via a software interface. This control is achieved by a network of miniaturized controllers, incorporated into the structure of the metasurface. The controllers receive programmatic directives and perform simple alterations on the metasurface structure, adjusting its EM behavior. The required end-functionality is described in well-defined, reusable software modules, adding the potential for hosting multiple functionalities concurrently and adaptively. VISORSURF will study in depth the novel and unexplored theoretical capabilities of the HyperSurface concept. Two experimental prototypes will be implemented: a switch-based fabric array as the control medium; and a Graphene based, making use of its exquisite properties to provide finer control. A real pilot-application will demonstrate the HyperSurface potential to adapt to changes in their environment, to interconnect to smart control loops and make use of Information Technology (IT) programming concepts and algorithms in crafting the EM behavior of materials.", "To": ["2020-06-30, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-01-2016-2017 - FET-Open research and innovation actions"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Greece"], "Activity": ["Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["736876"], "Call_for_Proposal": ["H2020-FETOPEN-1-2016-2017"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Cdon-Hh Interaction: functional in vivo analysis in zebrafish"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["CHI-ZEF"], "Technology_Description": "Patterning of the vertebrate optic vesicle into proximal/optic stalk and distal/neural retina involves midline-derived Hh signalling, which promotes stalk specification. At the neural retina/optic stalk border, the cell adhesion molecule Cdon binds Hh, acting as a decoy receptor to protect the neural retina from Hh activity. How Cdon controls Hh dispersion, what is the destiny of the Hh protein accumulated at the neural retina/optic stalk boundary, whether Cdon participates in the release of Hh from its producing cells or whether Cdon has Hh-unrelated functions in the neural retina are the arising and still unanswered questions I aim to tackle in this proposal. Using the zebrafish as a model system and CRISPR/Cas9 technology I will first generate unprecedented tools to follow in vivo Cdon/Hh interaction, and then address how Cdon, expressed in both the ventral diencephalic midline and the neural retina, shapes the gradient of Hh responsible for proximo-distal patterning of the eye. I expect that the development of this proposal will provide significant advance on how morphogenetic signalling pathways operate, ultimately reverting into the field of regenerative medicine and clinical research related to congenital ocular malformations.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-07-01"], "Project_ID": ["740916"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FUNDACION IMDEA ALIMENTACION"], "EU_Contribution": ["EUR 257 191,20"], "Project_Title": ["Small open reading frames (smORF) as novel modulators of disorders of dietary excess"], "Total_Cost": ["EUR 257 191,20"], "Country": ["Spain"], "Project_ACR": ["LIPMETIN-sURFing"], "Technology_Description": "Dietary excess is the major origin of cardiovascular diseases and remains the leading cause of mortality. Due to difficulties with bioinformatics detection and experimental analysis, along with their sheer numbers, small open reading frames (smORF) \u2013of fewer than 100 amino acids\u2013 have been largely disregarded. Advances in bioinformatics, RNA-sequencing (ribosome profiling), biochemical (peptidomics) and functional (genetic) screens, suggest that a large amount of smORF are transcribed and sometimes widely conserved. However, how much of these smORF-encoded peptides or small proteins (microproteins (MPs)) are translated into a functional peptide is largely unknown. Moreover, whether food bioactive components modulate the expression of MPs remains complete obscure. Thus, the main goal of this project is to search for MPs that regulate lipid metabolism in the intestine in response to dietary excess. The intellectual merits of this proposal are threefold. First, it will use cutting-edge technology to search for novel functional MPs. Second, it will address a new group of novel potential players not previously addressed in lipid metabolism, providing a novel insight into disease mechanism and innovative therapeutic strategies. Last, by testing two common food bioactive components from our healthy Mediterranean diet, we will open up a completely new field of research in the area of nutrition and health. The research approach will involve (i) a genome-wide peptidomic screen and ribosome profiling analysis of lipid-induced intestinal MPs, (ii) the use of in vivo and in vitro biochemical approximations to validate the function of the selected intestinal peptide, and (iii) the use of dietary components hydroxytyrosol and the omega-3 polyunsaturated fatty acid DHA as proof of concept that MPs can be modulated by our diet food bioactive. This project is framed in the \u201cFood & Healthy Diet and Biotechnology\u201d research area in the European Union's Framework Programme HORIZON 2020", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-11-01"], "Project_ID": ["746435"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION"], "EU_Contribution": ["EUR 187 419,60"], "Project_Title": ["Genomic binding of transcription factors as a function of DNA affinity and chromatin."], "Total_Cost": ["EUR 187 419,60"], "Country": ["Switzerland"], "Project_ACR": ["TF-bind Determinants"], "Technology_Description": "Transcription factors (TFs) read cis-regulatory information encoded in the genome and by doing so, they establish gene expression patterns. However, TFs must compete with structural chromatin proteins such as nucleosomes for access to DNA, and this may partially explain why only a fraction of their sequence motifs in the genome are actually bound. It is unclear what features discriminate used from unused sites with similar motifs, in vivo, though it is likely that sensitivity of TFs to chromatin is critical for normal gene expression. For example, some TFs have reduced chromatin sensitivity, termed pioneer-factors, and are able to drive differentiation; even these bind a minority of cognate motifs in the genome. Such factors may nevertheless modify chromatin and expose motifs for TFs with higher sensitivity. Alternatively, chromatin proteins and modifications may be intrinsically directed by unidentified DNA sequence features. Though little is known about determines of TF-chromatin sensitivity, it is likely a function of DNA affinity and the ability to recruit chromatin-modifying activity.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Research Organisations"], "From": ["2017-04-01"], "Project_ID": ["748760"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ASTON UNIVERSITY", "CORK INSTITUTE OF TECHNOLOGY", "FUNDACIO INSTITUT CATALA DE NANOCIENCIA I NANOTECNOLOGIA", "THE UNIVERSITY OF BIRMINGHAM", "Teer Coatings Limited"], "EU_Contribution": ["EUR 720 000"], "Project_Title": ["Diamond-based nanomaterials and nanostructures for advanced electronic and photonic applications"], "Total_Cost": ["EUR 1 102 500"], "Country": ["United Kingdom", "Ireland", "Spain", "United Kingdom", "United Kingdom"], "Project_ACR": ["D-SPA"], "Technology_Description": "We are proposing a 4-year program of knowledge transfer and networking between Aston University, UK (Aston), Cork Institute of Technology, Ireland (CIT), Institute of Nanoscience and Nanotechnology, Spain (ICN2), University of Birmingham, UK (UoB), Zhejiang University of Technology, China (ZJUT), Nanotechplamsa Ltd, Bulgaria (NPL), B&T composites, Greece (B&T), National Institute for Research and Development in Electrical Engineering, Romania (ICPESA), and Teer Coatings Ltd, UK (TCL). ", "To": ["2021-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-04-01"], "Project_ID": ["734578"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["UNIVERSITY OF GLASGOW", "UNIVERSITY OF GLASGOW"], "EU_Contribution": ["EUR 1 957 573,75"], "Project_Title": ["A study of the roles of the immune and inflammatory systems in hypertension."], "Total_Cost": ["EUR 1 957 573,75"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["InflammaTENSION"], "Technology_Description": "Hypertension is a common disease impacting 1 billion people worldwide, which leads to catastrophic cardiovascular complications. The cause of primary hypertension is unknown and the disease remains uncontrolled in many patients. By interrogating the key hypothesis that inflammatory dysregulation fundamentally controls development of hypertension and vascular remodelling, InflammaTENSION provides a new paradigm for the management of the disease, with the potential to lead to identification of novel therapeutic targets to control hypertension. InflammaTENSION will result in the discovery of novel biomarkers, capable of identifying patients who could benefit from such immune targeted therapies. Importantly, we already made the seminal observation that the immune system not only mediates target organ damage, but is essential for the development of hypertension. This finding has initiated numerous studies, that defined the roles of pro-inflammatory T cells, monocytes and anti-inflammatory T regulatory cells. However, our current knowledge remains very fragmented and so far has not been applied to human pathology. InflammaTENSION will for the first time advance the knowledge procured in rodent models into human studies. By combining clinical translational and model mechanistic studies it will identify novel inflammatory factors that can control immune mechanisms of hypertension. We will: (1) characterize the immunophenotypic signature of human hypertension; (2) define key concepts in cytokine biology of hypertension with TNF-\u03b1 and IL-6 as key exemplars; (3) understand how chronic cytokines regulate the T cell dependent mechanisms of hypertension. InflammaTENSION will go beyond current state-of-the-art through comprehensive combination of immunology and cardiovascular medicine to create a new understanding of how the immune system may lead to human hypertension and will have major impact on the field, enabling translation of these exciting findings to clinical practice.", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["726318"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["Fundacion IMDEA Energia", "Fundacion IMDEA Energia"], "EU_Contribution": ["EUR 1 998 407"], "Project_Title": ["Membrane-Free Redox Flow Batteries"], "Total_Cost": ["EUR 1 998 407,01"], "Country": ["Spain", "Spain"], "Project_ACR": ["MFreeB"], "Technology_Description": "The environmental concerns over the use of fossil fuels have promoted great interest in generating electric energy from renewable sources such as solar and wind. However, the intermittent nature of those resources demands high performing and cost-effective energy storage systems. Redox Flow Batteries (RFBs) present several advantages, namely, total decoupling of power and energy densities and the possibility of rapid mechanical charging by substituting spent electrolytes with fresh ones. The major issues of the current Vanadium RFBs are the high price and toxicity of vanadium components and the high cost and low performance of the ion-selective membranes they require. ", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-06-01"], "Project_ID": ["726217"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI PERUGIA", "UNIVERSITA DEGLI STUDI DI PERUGIA"], "EU_Contribution": ["EUR 1 883 749,68"], "Project_Title": ["Dissecting to hit the therapeutic targets in nucleophosmin (NPM1)-mutated acute myeloid leukemia"], "Total_Cost": ["EUR 1 883 749,68"], "Country": ["Italy", "Italy"], "Project_ACR": ["ContraNPM1AML"], "Technology_Description": "Acute myeloid leukemia (AML) is a group of hematologic malignancies which, due to their molecular and clinical heterogeneity, have been traditionally difficult to classify and treat. Recently, next-generation, whole-genome sequencing has uncovered several recurrent somatic mutations that better define the landscape of AML genomics. Despite these advances in deciphering AML molecular subsets, there have been no concurrent improvements in AML therapy which still relies on the \u2018antracycline+cytarabine\u2019 scheme. Hereto, only about 40-50% of adult young patients are cured whilst most of the elderly succumb to their disease. Therefore, new therapeutic approaches which would take advantage of the new discoveries are clearly needed. In the past years, we discovered and characterized nucleophosmin (NPM1) mutations as the most frequent genetic alteration (about 30%) in AML, and today NPM1-mutated AML is a new entity in the WHO classification of myeloid neoplasms. However, mechanisms of leukemogenesis and a specific therapy for this leukemia are missing. Here, I aim to unravel the complex network of molecular interactions that take place in this distinct genetic subtype, and find their vulnerabilities to identify new targets for therapy. To address this issue, I will avail of relevant pre-clinical models developed in our laboratories and propose two complementary strategies: 1) a screening-based approach, focused either on the target, by analyzing synthetic lethal interactions through CRISPR-based genome-wide interference, or on the drug, by high-throughput chemical libraries screenings; 2) a hypothesis-driven approach, based on our recent gained novel insights on the role of specific intracellular pathways/genes in NPM1-mutated AML and on pharmacological studies with \u2018old\u2019 drugs, which we have revisited in the specific AML genetic context. I expect our discoveries will lead to find novel therapeutic approaches and make clinical trials available to patients as soon as possible.", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["725725"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITY OF LEEDS"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["How insulin resistance in the dorsal vagal complex affects glucose metabolism and feeding behaviour"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["CNS-Insuin-Res"], "Technology_Description": "The central nervous system (CNS) integrates peripheral hormonal signals to regulate glucose homeostasis and feeding behavior. Obesity can cause the development of insulin resistance in the brain and completely disrupt the regulative functions of the CNS. Restoring the brain\u2019s ability to modulate metabolic functions could be very important to prevent the negative outcomes of obesity and diabetes. The Dorsal Vagal Complex (DVC) in the brainstem senses insulin to regulate glucose metabolism and feeding behavior in rodents. Three days of high fat diet feeding (HFD) is sufficient to completely disrupt the insulin response, thus causing an increase in blood glucose levels and overnutrition. I propose to understand the molecular events that trigger the development of insulin resistance in the DVC and understand the neuronal networks involved in the regulation glucose metabolism and feeding behavior in the DVC. I will use a combination of in vitro molecular approaches and in vivo physiological readouts to shed light on the physiological functions of this area of the brain. Identification of novel target molecules that are involved in the development of insulin resistance may also provide the basis for the development of new pharmacological approaches to counteract the development of obesity and diabetes.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["752408"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS"], "EU_Contribution": ["EUR 152 653,20"], "Project_Title": ["The origin of the Galactic magnetic field"], "Total_Cost": ["EUR 152 653,20"], "Country": ["Greece"], "Project_ACR": ["ORIGAMI"], "Technology_Description": "Magnetic fields lie at the heart of essentially all the outstanding problems in galactic evolution. However, the measurement of interstellar magnetic fields is very challenging. We can either measure the strength or the direction of the magnetic field vector in different regions of the Milky Way. Clearly, in order to assess the impact of the magnetic field in the core processes of galactic evolution, such as star formation and stellar feedback, we need to complement the observations with simulations of the magnetic field evolution.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Greece"], "Activity": ["Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555"], "From": ["2017-06-01"], "Project_ID": ["749073"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY", "TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["The development of Personalised Host Response Diagnostic kit"], "Total_Cost": ["EUR 150 000"], "Country": ["Israel", "Israel"], "Project_ACR": ["PHRD"], "Technology_Description": "Drug resistance is a major reason for failure in cancer chemotherapy and/or modern targeted drugs. While tumours usually initially respond to therapy, resistance occurs within several cycles of treatments, or later on when patients are off therapy. Until recently, acquired and intrinsic resistance mechanisms for therapy were thought to be solely tumour driven. They are usually measured after tumours relapse or after several lines of treatments. However, in our ERC starting grant (HostResponse No. 260633), we found a novel way to predict resistance to therapy, already after 24 hours after the first drug administration. This discovery resulted in a new stream of research by means of published papers and the formation of special interest groups in cancer research and pharmaceutical disciplines that tackle this paradigm shift in cancer therapy. During our discussions with the cancer community, a clear need has emerged for a Specific Host-Driven Resistant Mechanisms (SHDRM\u00ae) diagnostic platform which will serve two (closely connected) markets:(1) the research community \u2013 enabling researchers to further examine this new paradigm; and (2) Clinicians- enabling oncologists to identify each patient specific host driven resistance mechanism and repurpose off-the-shelf drugs to counteract the specific factor driving the resistance. PHRD goal is to technically validate and develop a diagnostic platform Prototype for both markets including a clinical study design report which will enable to secure our partners including drug manufacturers, diagnostic providers, and the research community to commit to jointly push the new PHRD standard.", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["737467"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI FIRENZE", "UNIVERSITA DEGLI STUDI DI FIRENZE"], "EU_Contribution": ["EUR 1 689 272"], "Project_Title": ["Economic Uncertainty and Fertility in Europe"], "Total_Cost": ["EUR 1 689 272"], "Country": ["Italy", "Italy"], "Project_ACR": ["EU-FER"], "Technology_Description": "EU-FER is a project about Economic Uncertainty and FERtility in EUrope. Economic uncertainty may be interpreted as an individual risk factor, mainly related to the labour market (e.g. unemployment, short-term contract jobs, underemployment, or a combination of these), but it may also be conceptualized as a macro-level phenomenon, reflecting the general uncertainty felt by people in times of economic turbulence. The recent Great Recession, spanning 2007 to 2009 and featuring downturns in both financial and labour market fortunes, has fuelled interest in understanding whether economic uncertainty, which does not appear to be a transient phenomenon, affects fertility.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["725961"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITY OF LEEDS", "UNIVERSITY OF LEEDS"], "EU_Contribution": ["EUR 1 985 996"], "Project_Title": ["The role of minerals in the oceanic carbon cycle"], "Total_Cost": ["EUR 1 985 996"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["MINORG"], "Technology_Description": "The oceanic carbon cycle is key for regulating the Earth system because, in sediments and seawater, the balance between the degradation and preservation of organic carbon (OC) exerts a first order control on atmospheric CO2 and O2. In sediments, OC is preserved over millions of years, while in seawater, a dissolved form of recalcitrant OC has been recently recognised as critical to OC storage over anthropogenic timescales. Both sedimentary and seawater OC are derived from living organisms, and should therefore be easily degraded. Their persistence is therefore profoundly puzzling. Quite simply we do not know how or why OC is preserved. A long-standing hypothesis suggests that protection of OC inside minerals might account for the vast OC stores preserved in sediments. In a NEW hypothesis, based on recent work by the PI and proposed here for the first time, the interaction of OC with minerals might ALSO account for the even larger stores of dissolved OC preserved in seawater. Together these concepts could revolutionise our understanding of OC degradation and preservation, but the extent to which minerals preserve OC in sediments and seawater is (still) unknown, largely because the mechanisms that control how OC interacts with minerals are almost entirely unconstrained. MINORG will quantify the role of minerals in the preservation of OC for the first time, by combining cutting-edge molecular-level techniques with the first ever comprehensive and fully integrated experimental and modelling campaign, to determine in unprecedented detail the exact mechanisms responsible for the interaction of OC with minerals, and its subsequent degradation and preservation behaviour. MINORG hypothesises that minerals play a MAJOR role in the preservation of OC, in both its sedimentary and seawater forms, and is uniquely poised to test this. This project will majorly contribute to our quantitative understanding of the oceanic carbon cycle, and so to predicting current climate change.", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["725613"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["INSTITUTO NACIONAL DE INVESTIGACIONY TECHNOLOGIA AGRARIA Y ALIMENTARIA OA MP", "INSTITUTO NACIONAL DE INVESTIGACIONY TECHNOLOGIA AGRARIA Y ALIMENTARIA OA MP"], "EU_Contribution": ["EUR 1 866 046"], "Project_Title": ["Teleost mucosal B1-like lymphocytes at the crossroad of tolerance and immunity"], "Total_Cost": ["EUR 1 866 046"], "Country": ["Spain", "Spain"], "Project_ACR": ["TEMUBLYM"], "Technology_Description": "B cells are one of the main players of immunity, responsible for the production of immunoglobulins (Igs). In 2011, I was granted an ERC Starting grant to undertake the phenotypical and functional characterization of teleost B lymphocytes based on the hypothesis that they do not behave as mammalian B2 cells (conventional B cells) but closely resemble mammalian innate B1 lymphocytes involved in extrafollicular T-independent (TI) responses. Since then, my laboratory has gathered considerable evidences that strengthen this hypothesis. These studies were mostly carried out in central lymphoid compartments, but did not address how teleost B1-like cells regulate the delicate balance between immunity and tolerance at mucosal interfaces, in species lacking follicular structures. In this new project, I want to pursue my studies on B lymphocyte functionality, focusing on how teleost mucosal B cells are regulated, still under the assumption that fish B lymphocytes resemble better a B1 model. We will study how fish B cells differentiate to antibody secreting cells (ASCs) and establish extrafollicular long-term memory, taking into account novel results in mammals that have challenged traditional paradigms and revealed that long-term immunological memory can be established through TI IgM B1-like responses. Furthermore, we will also study the role of IgD in the gills, as previous studies from my group suggest that this Ig plays a key role in the regulation of immunity in this specific mucosa, as it seems to do in humans in areas such as the upper respiratory tract.", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-04-01"], "Project_ID": ["725061"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["ECOLE NORMALE SUPERIEURE", "ECOLE NORMALE SUPERIEURE"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Pushing the frontiers of biological imaging with genetically encoded fluorescence switches"], "Total_Cost": ["EUR 2 000 000"], "Country": ["France", "France"], "Project_ACR": ["FLUOSWITCH"], "Technology_Description": "Biological imaging is essential for revealing the inner workings of living systems. Among the numerous imaging modalities, light microscopy has revolutionized biological research. In addition to advances in optics and detectors, imaging has benefited from the development of molecular tools to observe biomolecules in action. Although the last decade\u2019s breakthroughs in imaging have led to new discoveries in biology, there are still extraordinary opportunities for basic and clinical research in further advancing imaging capabilities. This project proposes to develop new classes of probes to advance biological imaging and allow the study of biological processes in all their complexity. First, I propose to push the boundaries of multiplexing and super-resolution imaging in living cells developing a new class of fluorogenic probes that act as genetically encoded fluorescence on/off switches. Highly multiplexed images will be built up over sequential activation of orthogonal fluorescence on/off switches, while continuous switching will allow implementing innovative dynamic super-resolution techniques in living cells. Then, I will develop dynamic fluorescence on/off switches enabling to reveal the dynamics of intracellular processes, focusing in particular on the visualization of interaction dynamics in real-time, and the dynamic detection of endogenous molecules (e.g. proteins, nucleic acids) in living cells. The final part will be dedicated to the development of probes acting as molecular integrator switches to identify active cell circuits in whole tissues or organisms through permanent labeling of transiently activated cells. Overall, this project will enable to push back the frontiers of biological imaging providing innovative tools to interrogate quantitatively and comprehensively living systems at the molecular, cellular and network levels.", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["724705"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["HELSINGIN YLIOPISTO", "HELSINGIN YLIOPISTO"], "EU_Contribution": ["EUR 2 211 564,75"], "Project_Title": ["Individualizing statin therapy by using a systems pharmacology decision support algorithm"], "Total_Cost": ["EUR 2 211 564,75"], "Country": ["Finland", "Finland"], "Project_ACR": ["IndiviStat"], "Technology_Description": "Background: Statins are essential drugs in the treatment of hypercholesterolaemia and are among the most prescribed drugs worldwide. The response to statin therapy varies widely between individuals. While most patients show good efficacy, a significant proportion of individuals show poor or even a lack of cholesterol-lowering efficacy. Moreover, a number of patients experience adverse drug reactions. These together with the lack of immediate effect on well-being likely explain the relatively poor adherence to statin therapy. Poor adherence to statins in turn increases the incidence of cardiovascular events and mortality.", "To": ["2022-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["725249"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITAT WIEN", "UNIVERSITAT WIEN"], "EU_Contribution": ["EUR 1 498 279"], "Project_Title": ["Illuminating Functional Networks and Keystone Species in the Gut"], "Total_Cost": ["EUR 1 498 279"], "Country": ["Austria", "Austria"], "Project_ACR": ["FunKeyGut"], "Technology_Description": "We live in an intimate symbiosis with our gut microbiota, which provides us services such as vitamin production, breakdown of dietary compounds, and immune training. Sequencing-based approaches that have been applied to catalogue the gut microbiota have revealed intriguing discoveries associating the microbiome with diet and disease. The next outstanding challenge is to unravel the many activities and interactions that define gut microbiota function.", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["714623"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["UNIVERSITAT JAUME I DE CASTELLON", "UNIVERSITAT JAUME I DE CASTELLON"], "EU_Contribution": ["EUR 1 999 071,53"], "Project_Title": ["Boosting Photovoltaic Performance by the Synergistic Interaction of Halide Perovskites and Semiconductor Quantum Dots"], "Total_Cost": ["EUR 1 999 071,53"], "Country": ["Spain", "Spain"], "Project_ACR": ["No-LIMIT"], "Technology_Description": "Photovoltaic conversion has the extraordinary property of transforming the solar energy directly into electric power. However, the available electrical power is known to be severely limited by the so-called Shockley-Queisser (SQ) photoconversion limit. The maximum efficiency for a single absorber is limited as photons with energy lower than the bandgap (BG) cannot be absorbed, and just an energy equivalent to the BG can be used for photons with higher energy than the BG, due to thermalization. Tandem cells have overcome this SQ limit upon exploiting complex and expensive configurations. Alternative approaches, even with higher potentiality, as Intermediate Bandgap Solar Cells (IBSCs) have not reached the expected performance mainly due to the limitations introduced by the monocrystalline matrix. The incorporation of quantum dots (QD) to create the IB produces layer strain and defects that limit the cell performance. No-LIMIT proposes to revamp IBSCs concept, using polycrystalline halide perovskites (HP) host matrix in order to take benefit from the strain relaxation at polycrystalline materials and from HP benign defect physics. HPs show an outstanding performance even when they are grown in a porous structure, indicating that their excellent transport and recombination properties are preserved with embedded materials. No-LIMIT will exploit this potentiality by using the states of embedded QD as IB in IBSC with HP matrix. The project will focus on the preparation of HPs-QD systems with enhanced light collection efficiency preserving charge transport, recombination and stability. No-LIMIT will study the properties and interactions of the HP and QD materials developed, as well as injection, recombination and transport properties in the coupled system. The combination of these strategies will build a ground-breaking synergistic system able to break the SQ limit. The achievements of IBSC, together with the intermediate steps, will have a colossal impact on photovoltaics", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["724424"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 200 194,80"], "Project_Title": ["Live, In vivo Visualisation of liver Regeneration in Zebrafish After Photoablation of hepatocytes"], "Total_Cost": ["EUR 200 194,80"], "Country": ["Denmark"], "Project_ACR": ["LIVERZAP"], "Technology_Description": "The specialised tissue architecture of the liver is crucially important for its essential metabolic functions in the body. The liver has the unique regenerative capacity to restore lost architecture when damaged. However, this remodelling process is compromised in chronic liver disease by scarring and cirrhosis. Often the only treatment is organ transplantation, thus the development of novel therapies is of vital importance. The necessary understanding of the dynamic cell rearrangement driving restoration of liver architecture has been limited by temporally static histological analyses of fixed regenerating tissue. Real-time monitoring of the mammalian liver is hindered by tissue opacity and deep organ position, whereas the surface location of the zebrafish liver and larval transparency makes this species uniquely suited for live, in vivo imaging of regeneration. LIVERZAP will generate a detailed map of the different cell behaviours driving restoration of liver architecture by pioneering real-time, in vivo imaging of regeneration in zebrafish. This will be achieved by: i) generating a novel, photoactivatable method for rapid hepatocyte ablation and ii) developing a deep tissue, 2-photon microscopy live imaging protocol. The molecular factors controlling the identified cell behaviours will be screened for using SILAC-based proteomics. To realise LIVERZAP, expertise in liver research, deep tissue microscopy and proteomics within the host environment will be combined with the fellow\u2019s live imaging experience. LIVERZAP will generate excellent new tools for the regeneration community and greatly enhance the fellow\u2019s competencies in specialised techniques, including cutting-edge microscopy systems and optogenetics. The outcomes of LIVERZAP will produce essential insights into the cellular and molecular mechanisms driving restoration of liver architecture following injury, providing a platform for the long-term development of therapies for human liver pathologies.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["751085"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["TEL AVIV UNIVERSITY", "TEL AVIV UNIVERSITY"], "EU_Contribution": ["EUR 1 971 875"], "Project_Title": ["Aligning pigmentation and repair: a holistic approach for UV protection dynamics"], "Total_Cost": ["EUR 1 971 875"], "Country": ["Israel", "Israel"], "Project_ACR": ["UVdynamicsProtection"], "Technology_Description": "The human body takes different measures in order to protect itself against the results of UV exposure and its accompanied hazards, such as skin cancer. Despite extensive studies regarding the molecular regulation of the two main UV protection mechanisms, namely, the DNA repair system and the pigmentation system, a comprehensive theory that simultaneously accounts for the two systems is still missing. Hence, the ground-breaking goal of this proposal is to elucidate, for the first time, the dynamic control used to schedule and synchronize the UV protection subsystems. ", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["726225"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["LUNDS UNIVERSITET"], "EU_Contribution": ["EUR 173 857,20"], "Project_Title": ["Theory, Computation and Application of Characteristics Modes"], "Total_Cost": ["EUR 173 857,20"], "Country": ["Sweden"], "Project_ACR": ["TECAM"], "Technology_Description": "The proposal focuses on Theory of Characteristic Modes(TCM), a reasonably general methodology to systematically design and analyse arbitrary antennas in wireless communication systems by providing accurate physical insights of the working mechanism. With the rise of the diverse and complex requirements of modern antenna systems, the existing TCM is not sufficiently effective to handle critical design problems such as multi-scale vehicular antenna systems and large-scale massive MIMO base station arrays, which leads to an urgent need for further improvement of TCM. ", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["749598"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Role of calcium fluxes in mitochondrial dynamics"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["MITODYN"], "Technology_Description": "Mitochondria house hundreds of biochemical reactions involved in processes critical for the survival and homeostatic adaptation of the cell. Mitochondria are highly dynamic organelles, which adapt their shape and network depending on the cellular needs. As mitochondria play a central and unique role in metabolism, our understanding of the complex network of interrelations between mitochondria and other organelles has crucially changed our view on the cell biology of mitochondria and a new biology and pathophysiology of this organelle are emerging. Mitochondria are in dynamic contact with the endoplasmic reticulum (ER) and this specialized contact is essential for a number of relevant processes, including mitochondrial dynamics, lipid exchange, calcium homeostasis and apoptosis. The Mitochondrial Calcium Uniporter (MCU) and some of its regulators (MICU1-3, EMRE) have recently been identified as the key complex regulating mitochondrial calcium uptake with some already identified functions. The goal of this project is to define the complete interactome of the Mitochondrial Calcium Uptake Machinery (MCUM) in different physiological conditions and to characterize the functions associated to this complex. To address these goals, an unbiased proteomic analysis will be performed, both in cellulo (human cells) and in vivo (zebrafish), to identify the interactors of the MCUM at steady state and under different cellular stresses using the BioID technic. The mechanisms involving the MCUM in the regulation of mitochondrial dynamics, apoptosis and cell migration will be unravelled using molecular and cell biology experiments coupled with the most recent advances in microscopic analysis. Finally, we will explore the relevance of these findings in the physiopathology associated to mitochondrial diseases using cell lines derived from patients harbouring a MCUM dysfunction.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["749926"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITEIT GENT"], "EU_Contribution": ["EUR 172 800"], "Project_Title": ["Fiction, Imagination, and Early Cinema"], "Total_Cost": ["EUR 172 800"], "Country": ["Belgium"], "Project_ACR": ["FIEC"], "Technology_Description": "\"The project investigates two closely interrelated issues: what is the role of imagination in early cinema and what does it mean for a representational work to be fictional? Specifically, it asks what the criteria are according to which we categorize texts as fictional and what counts as proof for reconstructing the experience of historical spectatorship. The project innovatively proposes that the period between 1880 and 1915 provides a unique opportunity for construing how a representational medium becames employed in the production of fictions and the crucial role the discourse on imaginary engagement plays in this process. In other words, the project asks why we engage some films as fictions and other as documentaries despite the fact that they are both based on actuality material \u2013 photographs. For instance, why, when watching M\u00e9li\u00e8s\u2019 1898 The Astronomer\u2019s Dream or the Man in the Moon, do we nowadays regularly say that we are watching an astronomer whose gazing at the moon turns into a series of fantastical mishaps? Why do we engage such a film as a fiction rather than as a documentary of actors performing in front of painted sets? Especially if during the early era, such films were regularly seen as instances of \u201ccanned theater\u201d, i.e. as documentaries of theatrical performances. ", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["746619"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Near-term predictability of net primary production in the Atlantic Ocean"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["NeTNPPAO"], "Technology_Description": "The main goal of this research project is the improvement of near-term (i.e. seasonal to decadal) predictions of Net Primary Production (NPP) in the Atlantic Ocean. NPP is the rate of production of phytoplankton biomass, the primary source of food for marine animal life and thus a fundamental environmental variable to be taken into account in fishery management strategies. The activities proposed are based on a suite of simulations with an Earth System Model (ESM). These simulations include reconstructions of the biogeochemical state of the Atlantic ocean for the period 1960 to present and a set of near-term predictions initialized every 3 years for the period 1979 to present. The simulations are designed to test the ability of two different initialization techniques to provide predictive skill to the NPP prediction. One initialization technique is based on data-assimilation of physical fields only. As an absolute novelty, the second technique proposed is based on the reconstruction of 3D nutrient fields. This combines information from climatological nutrient fields and reconstructed water masses variability. This combination is meant to exploit the ability of Atlantic mode waters to propagate a signal on nutrient distribution on interannual timescales providing a source of predictability for nutrients and thus for NPP. Skill scores will be used to validate the near-term predictions derived from both techniques and the best performing one will be extended to 10-year forecast and initialization every year in order to obtain a complete evaluation of the predictive capability of the modeling system (ESM+initialization technique).", "To": ["2019-01-08, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-01-09"], "Project_ID": ["708063"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 212 194,80"], "Project_Title": ["New Frontiers in Modeling Planet-Disk Interactions: from Disk Thermodynamics to Multi-Planet Systems"], "Total_Cost": ["EUR 212 194,80"], "Country": ["Denmark"], "Project_ACR": ["DiskTorqueOnPlanets"], "Technology_Description": "Recent space missions such as CoRoT and Kepler have revolutionized exoplanetary science. Today, we know of thousands of systems with awide diversity of architectures, proving that our Solar System is not typical. Understanding how these systems form and evolve is currently one of the most active area of astrophysics. The processes that dictate the dynamics of planets play a fundamental role in shaping the architecture of the systems we observe. In the present paradigm, as planets accrete mass from the primordial disk, they are subject to interactions with it and with other planets. These interactions exert torques, and make the planets migrate. Disk-planet interactions depend strongly on the physical processes governing the dynamics of the disk. I demonstrated a clear example of this in a recent paper in Nature, showing that the disk heating by an accreting embryo have a strong impact on the torques. This proposal has two objectives with the potential to produce a leap forward in our understanding of the long-term evolution of planetary systems. (i) I will produce the most advanced framework to date for investigating planetary migration in magnetohydrodynamic disk simulations, including ohmic, ambipolar and Hall effects. I will do this self-consistently by considering the chemical evolution of the dusty gas. Calculating its ionization state and opacity, will moreover allow me to incorporate radiation more realistically. (ii) I will build on a new technique that I have developed, the use of 3D radially moving meshes. This groundbreaking technique enables to follow the migration of multiple planets allowing studying their long-range migration. I want to carry out this research program at The Niels Bohr Institute. The combined expertise of the groups in Copenhagen, together with their impressive computational resources, provide an unparalleled environment to achieve my research goals and develop myself as a leading international figure in this rapidly evolving field.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["748544"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE FRANCIS CRICK INSTITUTE LIMITED", "THE FRANCIS CRICK INSTITUTE LIMITED"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Hold it or let it go: a niche decision on cancer growth"], "Total_Cost": ["EUR 2 000 000"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["WHOLENICHE"], "Technology_Description": "The tumour microenvironment or niche is the vital non-cancerous compartment of the tumour structure. Thus, targeting its tissue-derived cells represents a promising avenue to better therapeutic interventions. However, knowledge about the tissue cells taking part of the tumour niche during early cancer development and later progression is lagging behind due to the difficulty of analysing and following early tissue changes in the surrounding of cancer cells in vivo. In our research proposal we will use a combination of original tools developed in the lab and state of the art technologies to overcome some of these constraints and expand our understanding of which cells in the niche support early cancer cell growth. We also aim to reveal their mechanism of action and identify approaches to block the niche supportive activity. Our five-year plan has three main objectives (I, II, III), which we will meet using two original strategies. With the first strategy we will visualize the early tumourigenic niche in vivo. This will allow us (I) to identify and characterize novel cellular components during dynamic niche evolution both in the context of metastatic colonization as well as during primary tumour onset. We will also use this original approach (II) to deepen our understanding of neutrophils in cancer, a particularly crucial emerging component of the cancer niche, whose role is still debated. ", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-04-01"], "Project_ID": ["725492"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 260 227,80"], "Project_Title": ["Very-Large-Scale Quantum Photonic Processing"], "Total_Cost": ["EUR 260 227,80"], "Country": ["Denmark"], "Project_ACR": ["VLS-QPP"], "Technology_Description": "Optical systems operating at the quantum regime have recently enabled the detection of gravitational waves; new forms of ultra-secure communications; and high-fidelity manipulation of quantum states for quantum computing. Maintaining this progress requires breakthroughs in quantum photonic architectures to process many optical modes with exceptional speed and precision. Fortunately, progress in optical interconnects has culminated in the development of silicon photonic integrated circuits, enabling photonic devices to be combined virtually losslessly at orders of magnitude higher component density than possible with traditional methods. Here, we propose to leverage these advances to meet the stringent requirements of optical quantum information processing bringing together state-of-the-art single photon source technologies and large-scale silicon photonic circuits: (1) Leveraging state-of-the-art silicon photonics fabrication processes to build a large-scale 10-photon quantum photonic processor; fully integrated with on-chip photon sources, pump engineering and reconfigurable circuitry. (2) Interfacing solid-state quantum emitters with silicon photonic circuitry, enabling deterministic generation and large-scale manipulation of single photon states. These very-large-scale quantum photonic processors (VLS-QPP) will provide several orders of magnitude speedups compared with current technologies, demonstrate practical quantum algorithms for quantum chemistry and machine learning, and provide a clear route towards scalable photonic quantum technologies. To enable these advances this fellowship proposes a clear training plan, at two world-leading institutions, towards developing the necessary diverse skill set to propel the field forward in new directions.", "To": ["2020-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["751016"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 1 834 975"], "Project_Title": ["Analysis, Verification, and Synthesis for Infinite-State Systems"], "Total_Cost": ["EUR 1 834 975"], "Country": ["Germany", "Germany", "United Kingdom"], "Project_ACR": ["AVS-ISS"], "Technology_Description": "The central objective of this project is to investigate key algorithmic verification questions concerning two fundamental mathematical structures used to model and analyse infinite-state systems, namely discrete linear dynamical systems and counter automata, in both ordinary and parametric form. Motivated especially by applications to software model checking (more specifically the termination of linear loops and predicate abstraction computations), as well as parametric real-time reasoning and the verification of Markov chains, we will focus on model-checking, module-checking, and synthesis problems for linear dynamical systems and one-counter automata against various fragments and extensions of Linear Temporal Logic (LTL) specifications. The key deliverables will be novel verification algorithms along with a map of the complexity landscape. A second objective is then to transfer algorithmic insights into practical verification methodologies and tools, in collaboration with colleagues in academia and industrial research laboratories.", "To": ["2020-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Research Organisations", "Volker Maria Geiss", "Tel.: +4968193255700", "Fax: +4968193255719", "Higher or Secondary Education Establishments"], "From": ["2015-08-01"], "Project_ID": ["648701"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Leggett-Garg test of a vibrating carbon nanotube"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["LeGaNa"], "Technology_Description": "Despite the undeniable success of quantum mechanics, the boundary between quantum and classical mechanics remains unclear. Leggett and Garg devised a class of inequalities that provide the script for a quantitative test to determine whether a macroscopic object would indeed be at all times in one of its distinct states or whether quantum mechanics would prevail. I will perform the first Leggett-Garg test on a massive moving object: a carbon nanotube resonator. This ambitious experiment would be a key accomplishment in mapping the persistence of quantum features in systems of increasing macroscopicity.", "To": ["2018-02-28, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["658989"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Molecular determination of Rif1-Associated Genomic Elements and their function in regulating genome activity and integrity"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["RAGES"], "Technology_Description": "DNA double-strand breaks (DSBs) are highly toxic and must usually be accurately repaired to prevent oncogenic mutations. However, DSBs also represent necessary intermediates of recombination events required to create genetic diversity in immune repertoires and the germline. These distinct cellular contexts require that DSBs are differentially metabolised to achieve the required genetic outcome. Thus a complex system has evolved to regulate DSB repair. Rif1 was recently identified as a critical regulator of DSB repair, recruited to chromatin at DSBs by the 53BP1 chromatin reader. However, little is known about how these proteins cooperate to alter the chromatin landscape at DNA damage sites, and how this influences DNA repair decisions. Understanding the molecular basis of these proteins function is paramount, as misregulation at the level of Rif1/53BP1 is known to drive disease: loss of either protein results in primary immunodeficiency, while an inability to counteract Rif1/53BP1-dependent activities during DNA repair is associated with genomic instability that drives carcinogenesis. Interestingly, recent evidence suggests that Rif1 may also mediate gene-repression in certain chromatin contexts. This raises the possibility that the manner by which Rif1 regulates transcriptional control may be similar to its role in DNA repair. In this proposal, I seek to test my hypothesis that Rif1 mediates repressive chromatin states to regulate both transcription and DNA repair outcomes. My preliminary work and an array of unique cell lines and molecular reagents developed by my host laboratory, provide me with a unique and timely opportunity to examine this fascinating protein, and develop a better understanding of potentially common regulatory mechanisms that govern transcription and DNA repair.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-03-31"], "Project_ID": ["656357"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Delineation of a brain circuit regulating energy expenditure to impact body weight"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["NeuroEE"], "Technology_Description": "Obesity is now a global epidemic with a significant and deleterious impact on human health. My career aim is to clarify the neural underpinnings of energy expenditure (EE) given that this makes a significant contribution to body weight. During my early career, I discovered a circuit linking the ventromedial hypothalamus (VMH) to brown adipose tissue (BAT) and inducing thermogenic beige (browning) white adipose tissue (WAT), regulating EE. Moreover, I found that the VMH-BAT axis is utilized by estrogen (Cell Metabolism, 2014) and nicotine (Diabetes, 2012) to increase EE and decrease body weight. My preliminary data indicate that a critical node between the VMH and BAT is the raphe pallidus (RPa), a brain region known to drive sympathetic tone to BAT. My immediate career aim is to clarify the neurochemical communicator receiving the VMH-EE related input and transmitting to BAT and browning. Given that the RPa is rich in the neurotransmitter 5-hydroxytryptamine (5-HT) which plays a role in thermoregulation, I hypothesize that 5-HT is a crucial component of my circuit. I propose to perform a Marie Sklodowska-Curie Fellowship (MSC) under Prof Lora Heisler\u2019s supervision, arguably the global leader in 5-HT obesity research. Her laboratory is in the Rowett Institute of Nutrition and Health, University of Aberdeen, an Institute with more than a century of focused state-of-the-art obesity and nutrition research. This will supply an optimal environment for a MSC providing me with the opportunity to broaden my research interests, and allowing me to construct an international network of obesity researchers. A MSC will also provide the opportunity for me to be trained in transferable next generation engineered genetic technology that will allow me to rigorously and definitively test my current research hypothesis and to provide state-of-the-art expertise that will form a platform for my future career.", "To": ["2018-01-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-02-01"], "Project_ID": ["660219"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Composite-particle approach to Symmetry Protected Topological Phases"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["CompositeSPTphases"], "Technology_Description": "The sum being greater than its parts is a common theme in condensed matter physics. Materials made of large numbers of simple constituents often exhibit intriguing and markedly distinct phases of matter with properties very different from any of the individual constituents. Understanding the possible phases of matter and identifying them in real materials is the central focus of this branch of physics. Roughly speaking, two categories of phases of matter exist--- conventional phases which show a geometrical pattern of order, and topological phases, where the order is more elusive and related to topological concepts. In the past three decades, topological phases have attracted a large amount of interest due to their tendency to exhibit highly robust quantum phenomena which has various applications in quantum engineering and metrology. The current frontier in the field aims at understanding the variety of novel topological phases which arise when some extra symmetries, such as time reversal, are not allowed to be broken. In this project we explore this new type of phase using the concept of composite particles --- an idea which has been extremely useful in previous studies of topological matter, but has not been applied in the symmetry-protected context previously. The fundamental idea behind our approach is to view symmetry protected topological (SPT) phases of spin/electron systems as conventional ferromagnets/superconductors/metals of composite objects. Besides its conceptual importance, such an approach will allow us to utilize our knowledge of conventional phases in the context of SPT phases and also derive microscopic models which realize these states of matter. It will thus increase the chance of discovering new SPT phases in nature.", "To": ["2017-03-31, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-04-01"], "Project_ID": ["657111"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITATEA DE STIINTE AGRONOMICE SI MEDICINA VETERINARA - BUCURESTI", "UNIVERSITATEA DUNAREA DE JOS DIN GALATI", "UNIVERSIDAD POLITECNICA DE MADRID"], "EU_Contribution": ["EUR 580 500"], "Project_Title": ["Researches on the potential conversion of conventional fish farms into organic by establishing a model and good practice guide"], "Total_Cost": ["EUR 580 500"], "Country": ["Romania", "Romania", "Spain"], "Project_ACR": ["ECOFISH"], "Technology_Description": "The conversion of conventional aquaculture farms in sustainable aquaculture farms help aquaculture businesses to achieve economic viability and competitiveness. Sustainable aquaculture is undoubtedly the management technique that has most contributed to support aquaculture businesses to adopt aqua-environmental measures for protection of the environment, natural resources and landscape.", "To": ["2019-05-31, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Romania"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-06-01"], "Project_ID": ["645691"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["CPNU - CENTAR ZA PROMOCIJU NAUKE IUMETNOSTI DRUSTVO SA OGRANICENOM ODGOVORNOSCU BEOGRAD", "INSTITUT MIHAJLO PUPIN", "UNIVERSITY OF NIS- FACULTY OF ELECTRONIC ENGINEERING", "UNIVERZITET U KRAGUJEVCU", "Faculty of Mathematics, University of Belgrade"], "EU_Contribution": ["EUR 144 143"], "Project_Title": ["Fall in Love wIth Research Tonight"], "Total_Cost": ["EUR 181 679"], "Country": ["Serbia", "Serbia", "Serbia", "Serbia", "Serbia"], "Project_ACR": ["FLIRT"], "Technology_Description": "The FLIRT proposes a project that is based on the idea that falling in love with science is just as exciting as falling in love with a real person, and shows how a passionate \u201ccrush\u201d can develop into real love.", "To": ["2015-11-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-NIGHT-2014 - European Researchers' Night (NIGHT)"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Serbia"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2014-05-01"], "Project_ID": ["633398"], "Call_for_Proposal": ["H2020-MSCA-NIGHT-2014"]}, -{"Partners": ["AARHUS UNIVERSITET", "UNIVERSITY OF KENT", "WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER", "MARTIN-LUTHER-UNIVERSITAET HALLE-WITTENBERG", "UNIVERSITA CATTOLICA DEL SACRO CUORE", "UNIVERZITA KARLOVA", "THE UNIVERSITY OF READING"], "EU_Contribution": ["EUR 3 651 149,88"], "Project_Title": ["The History of Human Freedom and Dignity in Western Civilization"], "Total_Cost": ["EUR 3 651 149,88"], "Country": ["Denmark", "United Kingdom", "Germany", "Germany", "Italy", "Czech Republic", "United Kingdom"], "Project_ACR": ["HHFDWC"], "Technology_Description": "The ETN has two aims: to a) train ESRs; b) investigate the The History of Human Freedom and Dignity in Western Civilization. ", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["676258"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 91 727,40"], "Project_Title": ["Deformations of fundamental Groups of REpresentATions"], "Total_Cost": ["EUR 91 727,40"], "Country": ["United Kingdom"], "Project_ACR": ["GREAT"], "Technology_Description": "The aim of this project is to consider X a smooth projective algebraic curve and a representation \u03c1 of \u03c01(X) into a semisimple Lie group G, and study deformations of \u03c1 when X deforms into a singular curve. This question will open a brand new direction in the theory of representations of fundamental groups and G-Higgs bundles. The main tool to approach the problem will be non- abelian Hodge theory to transform this topological question into the geometric one. Then we use recent new developments in the classification of representations together with new algebraic objects which recently appear in non-abelian Hodge theory to study this question. It will take us to the study the deformations of G-Higgs bundles together with deformations of harmonic bundles over X when X is a curve and varies.", "To": ["2016-12-31, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["654490"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["New Approaches to Metallo-\u03b2-Lactamase Inhibitors"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["MBLIs"], "Technology_Description": "The increasing problem of antibiotic resistance is a major global public health concern. In the EU 25,000 patients die each year due to infections caused by multi-resistant bacterial pathogens, and the EU spends at least 1.5 billion euro per year on healthcare costs. The \u03b2-lactam antibiotics are the most important antibiotics representing >60% of small molecules in clinical use. BLAs contain a \u03b2-lactam ring which is critical for penicillin-binding protein inhibition. However, BLA efficacy is declining due to resistance mechanisms including the widespread occurrence of \u03b2-lactamases, which catalyse \u03b2-lactam hydrolysis. Metallo-\u03b2-lactamases, long-considered as of little clinical relevance, now present a serious global threat to almost all BLAs, rendering the development of approaches to MBL inhibitors important. Unlike the serine \u03b2-lactamases, the MBLs are structurally and mechanistically unrelated to PBPs, and are not inhibited by current mechanism-based SBL inhibitors. Due to variations in MBL structures, a major challenge in MBL inhibition is the development of compounds with the breadth of selectivity necessary for clinical utility. Society is now in an alarming situation and there is a clear need for the development of an MBLI:\u03b2-lactam-based combination therapies. The aim of my proposed work is to pioneer, enable and inspire the generation of broad-spectrum MBLIs active against a panel of clinically representative MBLs, but inactive against human enzymes with related active sites. To obtain the desired objective, novel approaches are proposed and include the use of phosphonates and phosphinic acids for: (a) MBL-directed DCC coupled to analysis by non-denaturing ESI-MS and 31P-NMR, (b) 31P-NMR reporter screening method, (c) pre-equilibrated DCLs for MBL-directed DCC, and (d) the synthesis of modified inhibitors. The study will be interdisciplinary and encompass organic synthesis, biological MS/NMR, structural biology, and medicinal chemistry.", "To": ["2017-06-30, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-07-01"], "Project_ID": ["657314"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Using SP1 to control plastid development and yield in cereals"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["YIELDFACTOR"], "Technology_Description": "Recently, the host lab found that a novel ubiquitin E3 ligase, SP1, regulates the translocon of the outer chloroplast membrane (TOC), which is responsible for importing nucleus-encoded proteins into plastids. SP1 achieves this by promoting the degradation TOC components by the cytosolic 26S proteasome. This is the first time the ubiquitin proteasome system (UPS) has been shown to directly regulate plastid development and function. By increasing or decreasing SP1 levels in transgenic Arabidopsis plants, multiple effects of SP1 were observed; e.g., inefficient de-etiolation leading to low survival rates and delayed leaf senescence in sp1 null mutants (Science 2012, 338:655-9). Also, sp1 mutants are significantly more sensitive to stress (unpublished). These data suggest that SP1 is important for the differentiation and interconversion of different plastid types, and all of the effects are highly correlated with plant growth and yield. Thus, discovery of SP1 strongly suggests potential applications in agriculture, such as delaying leaf senescence to produce a staygreen phenotype, or controlling amyloplast development during grain development, by modifying SP1 expression. This project will investigate the function of SP1 in cereals, and assess the potential of SP1 for manipulating plastids to improve cereal yield. I will generate transgenic plants with manipulated SP1 expression in Brachypodium distachyon (a versatile cereal model) and Oryza sativa (rice). I will study the development of plastids in the transformants, and assess the transformants for beneficial effects on yield parameters, such as starch content, seed weight, germination, de-etiolation, leaf senescence and stress resistance. At the end, I will have thoroughly assessed the potential use of SP1 for manipulating cereal traits linked to yield. A major strength of the proposal is the complementarity of my expertise with that of the host. Our unique combination of skills will ensure success of the project.", "To": ["2018-03-06, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-03-07"], "Project_ID": ["659401"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Large Area Nanoparticle Deposition System"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["LANDS"], "Technology_Description": "I intend to travel to the University of Oxford and the lab of Dr. Moritz Riede and build a second generation version of the Large Area Nanoparticle Deposition System (LANDS) that I have designed and built during my PhD studies at Stanford University in the USA. This will be a flexible, particle-agnostic system that will be capable of depositing uniform films of nano- and micro-particles from solution. It is designed to emphasize scalability, high throughput and large area film uniformity and will be compatible with low-temperature flexible plastic and foil substrates and the devices built on them. Once complete, I will initially use the LANDS to deposit nanostructured thin films of metal nanowires to form transparent conductive electrodes for photovoltaic applications. I will continue to develop and explore the use of such metal nanowire films as replacements for industry standard transparent conductive oxides such as indium tin oxide (ITO) and fluorine doped tin oxide (FTO) especially in flexible devices.", "To": ["2017-08-11, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-08-12"], "Project_ID": ["659667"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Role of GABAergic microcircuits with different embryonic origins in the orchestration of early cortical dynamics in the awake mouse pup"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["GABACODEV"], "Technology_Description": "Because of its function in brain wiring and in the generation of early correlated activity patterns, the maturation of GABAergic transmission plays a key role in enabling brain complexity in higher mammals. Indeed, disruption of GABAergic circuitry at several time points can contribute to the generation of developmental disorders such as schizophrenia, autism or epilepsy (Le Maguerise and Moyner, 2013). Both in the murine hippocampus and neocortex, GABAergic interneurons have been shown to participate in the emergence of a precise temporal sequence of distinct correlated neuronal activity patterns during early postnatal development (Crepel et al., 2007; Allene et al., 2008). In particular, GABAergic cells with an extended and divergent axonal connectivity (operational \u201chub\u201d neurons) (Bonifazi et al., 2009; Picardo et al., 2011; Cossart, 2013) have been described to be capable of synchronizing single-handedly populations of cells in developing hippocampal slices (Bonifazi et al., 2009). This project builds up on a solid ground of unpublished in vitro data from the host lab indicating that a specific, but diverse functional subpopulation of GABA neurons could also operate as hub cells in the developing neocortex. Experimentally, it will benefit from recent technical developments from the host lab aiming at manipulating and visualizing the activity of single neurons in the awake mouse combining genetic and microscopy tools. Indeed, if operational hub neurons have been described in vitro, it remains unknown how they integrate into functional networks in vivo, and more generally how GABAergic activity shapes early cortical network dynamicsThis proposal aims at translating from the in vitro to the in vivo situation a multidisciplinary approach to investigate the functional contribution of specific microcircuits to the emergence of network dynamics during development.", "To": ["2017-03-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2015-04-01"], "Project_ID": ["660795"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Bioelectrochemical Sensing of Sexually Transmitted Diseases"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["BSSTD"], "Technology_Description": "The detection of sexually transmitted diseases (STDs) has become a serious medical concern around the globe, as the number of reported cases increases every year, particularly in the United Kingdom. Infection with STDs, such as Gonorrhea and Chlamydia can result in long term health issues, such as infertility, reproductive tract cancer, and poor perinatal outcome. The successful treatment of these diseases depends on a quick and reliable method of diagnosis, which will be the topic of this proposal. The overall goal of the proposed research is to develop a detection method for bacteria, associated with STDs, based on bioelectrochemical techniques.", "To": ["2018-09-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-15"], "Project_ID": ["702009"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Topological defects in nematic liquid crystals of active colloidal rods"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["TOPACT"], "Technology_Description": "Active liquid crystals are out-of-equilibrium systems that display intriguing dynamic phenomena, arising from the interplay between topological defects and collective motion. Here, we propose to experimentally study for the first time (i) the dynamics of topological defects in the active colloidal nematic phase and (ii) the interplay between these topological defects and collective dynamics, in three dimensions, at the single particle level, and with full control over the defects. To reach these objectives, we first use a combination of advanced colloidal synthesis and surface modification techniques in order to develop a model system of active colloidal rods of controlled size, aspect ratio and surface properties. We then confine this newly developed model system in microfluidic channels, where the colloidal rods form a nematic liquid crystal. Topological defects will be induced in the nematic phase using specific geometric constraints, which can be varied to control the locations and strengths of the defects, or by optical trapping techniques. Finally, we use state-of-the-art confocal microscopy and sophisticated image analysis techniques to follow, in real time and 3D real space, both the individual particle motion and the collective dynamics in the system. Our work will thus provide experimental verification of the intriguing link between topological defects and collective dynamics in active liquid crystals and inspire novel theories and simulation codes capable of capturing the intrinsic complexity of coupling structure, orientation and activity.", "To": ["2018-03-07, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-03-08"], "Project_ID": ["705024"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 97 727,40"], "Project_Title": ["CULTURAL POLICY AND CHORAL-HISTORICAL IDENTITY IN THE CHORAL/MUSICAL LIFEOF OXFORD UNIVERSITY COLLEGES AND HALLS IN THE 21ST CENTURY"], "Total_Cost": ["EUR 97 727,40"], "Country": ["United Kingdom"], "Project_ACR": ["OXFORDCHOIRS"], "Technology_Description": "This project presents an interdisciplinary study on the collective identities and (sometimes contested) cultures of collegiate choirs at University of Oxford (UOXF) and focuses on cultural-political issues and challenges facing the choral/musical tradition in UOXF colleges and halls in the 21st century. This project refers to extra-curricular music activities in the academic context, which relate to the current European Agenda for culture (accessible and inclusive culture and cultural heritage as well as referring to current societal challenges in Europe (social inclusion) whereas the project deals with musical activities in a somewhat elitist community. Drawing predominantly on the Sociology and Psychology of Music, as well as the contemporary history of Music and Cultural Policy, this interdisciplinary study can be divided into two main strands of research: A) Firstly from the perspective of students; to map the demographical background and social structures of members of the collegiate choirs and how the historical tradition affects and shapes the collective identities and individual cultures of the choirs. B) Secondly from the perspectives of staff/administrators; to study the cultural-political issues in \u2018governmental\u2019 decision making regarding the future of the collegiate choirs in terms of perspectives like politics of admission, competition for musical talent, forms of musical direction, gender perspectives, financial distribution and inequalities, musical hierarchies and the possible impact of cuts in public funding to musical school activities in general.", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["707827"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["In vivo pharmacogenetic investigation of 5-HT mechanisms in emotional learning"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["5HT-DREADD"], "Technology_Description": "Emotional health and well-being is widely accepted to be crucial for healthy life and the success of societies. Anxiety and depression are two common and debilitating emotional disorders, with highly negative social and financial implications. Serotonin (5-hydroxytryptamine; 5-HT) is thought to be critical to the healthy mood regulation and strongly implicated in the vulnerability to anxiety and depression. Importantly, accumulating evidence suggests that 5-HT\u2019s main influence is upon emotional learning rather than on mood directly. The objective of this proposal is to determine the neural mechanisms through which changes in 5-HT levels, within defined neuronal circuits, affect learning and memory for aversive emotional experiences. New pharmacogenetic techniques will be developed that allow the selective triggering of 5-HT neuron activation and then inhibition in the same animal. We will use this technology to stimulate or inhibit 5-HT release in the basolateral amygdala, a brain area that is crucial for aversive learning, whilst an animal is engaged in an emotional processing task. Through this we will learn how 5-HT modulates neuronal activity in the amygdala at critical time-points during the encoding and retrieval of aversive memories. The results from these studies will provide entirely new insights into how 5-HT modulates amygdala information processing and aversive learning. Understanding how 5-HT affects emotional learning will ultimately lead to a deeper understanding of healthy mood states and the biological mechanisms underlying vulnerability to disorders such as anxiety and depression.", "To": ["2018-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-07-01"], "Project_ID": ["709129"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Cambium genetics in Arabidopsis and Aspen: basic science meets wood production"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["WOODSofCHANGE"], "Technology_Description": "Multicellular organisms require an accurate coordination of multiple growth programs to develop. In plants, the lateral growth is the process by which stems and roots grow in diameter. Lateral growth is a pivotal process for plant development that (i) provides the mechanical stability that plants need to expand their growth and sustain their structures and (ii) brings about large amounts of extremely useful plant biomass, especially in the form of wood in trees. Lateral growth is mediated by a specialised group of stem cells collectively called cambium. Remarkably for such a crucial cell-type for plant development and biomass generation, very little is known about the genetic regulation of cambium. Dr. Agusti\u2019s lab has identified new strong potential cambium regulators through a novel approach that combines natural variation and Genome-Wide Association Studies (GWAS) in the model plant Arabidopsis thaliana. Based on the sophisticated skills that I acquired in the field of tree genetics and genomics and on the large experience on genomics techniques held in the lab of Dr. Agusti, I present a project that will:", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["655172"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Molecular mechanisms of arenavirus cell entry and antibody-mediated neutralization"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ARENAVIRUS"], "Technology_Description": "Over the last decades, multiple arenaviruses have emerged as zoonotic human pathogens. They cross the species barrier from their natural rodent hosts to humans and cause severe human disease. A key determinant of viral zoonotic transmission is the ability to bind the receptor molecules displayed on the surface of the host cell. Despite the threat these viruses cause to public health, little is known of how they infect the host and how they are targeted by the immune response. Furthermore, the treatment and prevention options are currently extremely limited. ", "To": ["2017-04-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-05-01"], "Project_ID": ["658363"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Regulation of (ADP-ribosyl)ation signalling in the DNA damage response: elucidating the function of a novel PARP1/ARTD1 interactor"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["PARPin"], "Technology_Description": "(ADP-ribosyl)ation is a dynamic post-translational modification synthesised by PARPs/ARTDs and regulates a diverse array of cellular processes, including the DNA damage response (DDR). The last decade has significantly improved our understanding of the key enzymes involved in (ADP-ribosyl)ation and the cellular pathways they function within. However, our understanding of how these enzymes are regulated is lacking and demands further investigation. In this proposal I seek to redress this.", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["701319"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 97 727,40"], "Project_Title": ["Pathologies of temporality. Abnormal experiences of time in mental disorders"], "Total_Cost": ["EUR 97 727,40"], "Country": ["United Kingdom"], "Project_ACR": ["Pathologies"], "Technology_Description": "The goal of the proposed research project is to analyze temporal disturbances in mental disorders and, as a result, to create a \u201cmap\u201d of pathological experiences of time. The map will be phenomenological in nature, i.e. cutting across existing classifications of mental disorders and avoiding untimely biological explanations. The project is highly interdisciplinary \u2013 it is situated at the intersection of phenomenology of temporality, philosophy of history and phenomenology of mental illness. It continues the tradition of philosophical-psychiatric reflections on time in mental disorders that started a century ago and that concerned temporal disturbances in conditions such as: addictions, amnesia, anxiety, dementia, depression, mania and schizophrenia. At the same time it enriches the existing empirical, clinical knowledge with non-medical interpretative schemes. The norm against which particular abnormalities will be assessed is going to be a value-based model of the relationship between past, present and future, and not value-free, physicalist notion of temporality. The major contribution that the project is going to make is bridging the gap between studies in philosophical textual analysis concerning temporality, which are theoretically sophisticated yet lack clinical references, and clinical papers, which will not serve its usual practical, medical function but pragmatically oriented philosophy. As a result, the study will constitute a major step toward answering two highly relevant philosophical-medical questions. First, can pathologies of temporality be interpreted as disorders in themselves, and not as epiphenomena built upon primary mental illnesses, and therefore provide ground for uniting otherwise separated categories of mental disorders? Second, how and to what extent can philosophical notions of time be applied not only to understanding of psychopathological phenomena but also to their treatment?", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["659205"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Functional magnetic resonance imaging of the cervical spinal cord at 7 Tesla"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["Spinal cord fMRI"], "Technology_Description": "Functional magnetic resonance imaging (fMRI) has become an indispensable tool in neuroscience to study human brain function non-invasively. However, translation of fMRI to investigate function of the second major component of the central nervous system, the spinal cord, has been severely hampered by technical difficulties. Two major challenges for spinal fMRI relate to the anatomy: (i) severe static image distortion caused by vertebrae and the lungs and (ii) dynamic signal instability introduced by breathing. I propose to address these problems by leveraging my expertise with cutting-edge technology for magnetic field compensation, available only to a few sites world-wide including my host institute in Oxford. These advances will enable me to take advantage of the signal-to-noise ratio improvement of ultra-high field (7 Tesla) MRI scanners, which has been clearly demonstrated in the brain but has remained elusive for the spine. The final stage of this project will deploy these methods on a collaborative project investigating the neurobiological mechanisms of pain in the spine. This project will enable me to build strategically on my dual training in engineering and medicine to develop an inter-disciplinary research profile at the interface of neuroscience and methodology.", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["659263"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Iridium Catalyzed Reductive Cyclization Cascades"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ICRED"], "Technology_Description": "The aim of this fellowship is to develop new reductive cyclization cascades of lactams and amides that establish these feedstock chemicals as important chemical precursors to reactive iminium ions which can be intercepted by pendant nucleophiles and exploited in carbon-carbon bond formation. A range of indole nucleophiles linked to amide and lactam functionality will be investigated for performance in the iridium catalyzed reductive cyclization cascades, and, based on successful proof of concept studies already performed in the Dixon group, a range of semi-saturated nitrogen-containing polycyclic structures possessing one or more stereocentres distributed over an architecturally complex framework should result. As well as studying diastereocontrol in the cascades, catalytic enantioselective variants will also be investigated. Finally, the application of the indole (spiro)cyclization reaction to the total synthesis of aspidospermidine will showcase the utility of the developed chemistry. This multidisciplinary Fellowship, based on high-quality and novel research at the University of Oxford, one of the top-research centres worldwide, will complement Dr Xie\u2019s skills and knowledge to improve his career possibilities and at the same time, Dr Xie\u2019s experience in creating catalytically active transition metal complexes will be critical for developing chiral versions of the iridium catalyst during the development of a catalytic asymmetric version of the reductive cyclization cascade.", "To": ["2018-07-10, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-07-11"], "Project_ID": ["707559"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Relative Role of Reproductive Isolating Barriers During Speciation"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["IsoBar"], "Technology_Description": "Understanding the appearance of reproductive isolation is essential for understanding mechanisms underlying the origin of species. This project aims at understanding the relative importance of different isolating barriers during adaptive speciation by looking at patterns of genomic divergence. I will use numerical modelling, analysis of RNAseq data from several biotypes (incipient species) of a model organism (pea aphid), and will perform mating experiments to address four research questions:", "To": ["2018-03-10, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-03-11"], "Project_ID": ["659847"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Novel topological phases of matter: From topological invariants to experiments"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["NovelTopo"], "Technology_Description": "Topological phases are exotic states of quantum matter characterized by a topological invariant of their ground state that guarantees the existence of unusual surface or edge modes with many special properties. In the last decade, the discovery of topological insulators has lead to a revolution in this field, in a remarkable joint effort between theory and experiment. Besides realizing a novel phase of matter, these materials can be exploited for many applications like in spintronics, and can serve as a platform to realize even more exotic phases like topological superconductivity and Majorana fermions. In this project, we combine the input of very recent experimental breakthroughs with theoretical guidance to propose realistic setups to characterize and manipulate these phases. ", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["705968"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Following a path of breadcrumbs: How fish recognize landmarks during navigation"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["FISHNAV"], "Technology_Description": "Reliable vision-based object recognition is of fundamental importance to a wide range of species; however, it can be difficult as the appearance of an object can vary greatly as a result of changes in viewpoint. Recognition during motion presents a particularly challenge as the appearance of an object continuously changes; a particular issue for animals that use landmarks to navigate. One recognition mechanism is to learn a two-dimensional snapshot of an object from a set viewpoint. The object can later be recognized once the appearance of the object matches the stored snapshot. Some animals reduce the number of required snapshots by employing \u2018active vision\u2019, where they follow identical routes between landmarks. For fish, the complexity of recognition is compounded by the fact that, unlike surface-bound animals, they can freely move vertically, which could potentially increase the number of approach views to an object. An alternate possibility is that fish have a \u2018view invariant\u2019 recognition system and can generalize learned representations of objects so that they can be recognized from different viewing angles. However, high-level visual functions, such as object recognition, are associated with complex mammalian brain structures and may be impossible for animals lacking similar neural circuitry. Despite these problems, we know that fish are capable of navigating efficiently using landmarks. The goal of this project is to investigate how fish recognize visual landmarks during navigation and to determine how they cope with self-orientation related changes in the appearance of objects during motion. Using behavioural experiments, we will test whether fish have view invariant recognition and/or if they employ active vision during navigation. The proposed project will further our knowledge of how fish perceive their visual environment as well as inform us about how conserved the mechanisms of object recognition are from an evolutionary perspective.", "To": ["2017-08-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-08-31"], "Project_ID": ["659684"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Quantitative characterization of cardiac tissue microstructure from Diffusion Tensor Imaging"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["DTI4micro"], "Technology_Description": "Cardiac Ventricular Remodelling (VR), i.e. the alteration of tissue microstructure that is a hallmark of several cardiac diseases, can have profound effects on cardiac function. A novel imaging technique, Diffusion Tensor Imaging (DTI) offers the potential to quantify VR in vivo and could thus have a significant impact on the assessment and treatment of cardiac disease. This project proposes the development of advanced analytical tools to evaluate its usability in the quantitative characterization of cardiac microstructure. The tools developed will aim at a) providing a mathematical description of normality in cardiac microstructure; and b) analysing local variation as an alternative descriptor for remodelling. A combination of preclinical and clinical validation will be performed, with histological slices used as ground truth for the identification of microstructural features. Emphasis will be placed on the development and application of a rigorous mathematical framework for the processing of tensor fields, including the quantification of local differences between tensors and the construction of statistical models for the quantification of pathology.", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["655020"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Organocatalysis at the service of total synthesis: Madangamine alkaloids"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ORSETOSY"], "Technology_Description": "This project will develop a new, highly enantioselective, state-of-the-art synthetic route to the madangamine alkaloids B, C and E based on a novel organocatalytic desymmetrization reaction as a key step, which will allow the rapid and efficient construction of the BC rings ready for subsequent advancement to the majority of the family members. Evaluation of the anti-cancer biological activity of the different madangamines and late stage intermediates will be carried out. This Fellowship project combines total synthesis, new asymmetric methodology development via organocatalysis and biological evaluation. It has been designed to augment and complement the research and transferable skills sets of the Marie Curie fellow, and will greatly enhance his career prospects accordingly. Through the training and the research results arising, the Fellowship will be beneficial to the fellow, the host institution and European science.", "To": ["2017-04-26, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-04-27"], "Project_ID": ["660125"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Silicon/Carbon Nano-Hybrid Lithium-Ion Battery Anode: Green Facile Scalable Synthesis Inspired by Thermosetting Polymers"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["LIB-Si anode"], "Technology_Description": "The last two decades have witnessed a great commercial success of lithium ion battery (LIB) in portable electronic devices and electric vehicles. However, current LIB technology cannot meet the rapid increasing demand from information technology and vehicle industry, primarily due to limited capacity and serious safety concern of graphite anode. Discovering new anode material with high capacity and good reliability has been a central issue. Because of its high theoretical capacity and excellent operation safety, silicon (Si) has attracted considerable attention as a promising anode to replace graphite. Nevertheless, dramatic volumetric change during lithiation/delithiation process causes severe pulverization and disconnection of electrode from current collector, leading to a fast capacity loss. To tackle these critical problems, a new concept to achieve facile, cost effective, green, and scalable synthesis of Si/carbon nanohybrid anode is proposed. By reducing Si particle size to the range below 10 nm and homogeneous embedding of Si nanoparticles into carbon buffer matrix, the volume change and associated stress can be effectively accommodated to improve the cyclability of the LIBs. Instead of conventional aqueous and/or organic solvents, three industrially widely used thermosetting resin monomer systems including vinyl ester resin, epoxy resin, and phenolic-formaldehyde resin are utilized as both solvent and carbon source. Cost effective silane coupling agents bearing appropriate chemical functional groups act as the precursor of Si and cross-linking agents of the thermosetting polymers. Ultra small Si nanoparticles are in situ formed and homogeneously embedded in the in situ formed porous carbon matrix by sequential photo/thermally induced polymerization, calcination in inert atmosphere, Magnesium thermal reduction, and KOH activation. The mechanism of control over morphology, crystallinity, dispersion, and composition of the Si/C nanohybrid anode and correspondin", "To": ["2017-09-13, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-14"], "Project_ID": ["655881"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Engineering Silicon Carbide Nanowires for Solar Fuels Production"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["Solarfuels"], "Technology_Description": "By 2020, the European Union aims to reduce greenhouse gas emissions by 20-30% and increase renewable energy share to 20%. This scenario has imposed urgent needs to develop fossil fuel alternatives like solar fuels. In order to produce solar fuels, the coupled reduction of CO2 and H2O is one of the most promising processes. However, the generation of efficient, stable and low-cost material for CO2/H2O reduction remains a big challenge. Silicon carbide nanowires (SiC NW) exhibit the unique properties of large surface-to-volume ratio, tuneable transport properties and quantum size effects, which is very promising for the reduction of CO2/H2O to produce solar fuels. To date, the studies on SiC NW for CO2/H2O reduction are limited due to the lack of (1) large-scale production techniques, (2) in situ characterization of the growth mode, and (3) there are no economical devices available for the evaluation of SiC NW. This project, SOLARFUELS, proposes the engineering of SiC NW for solar fuels production through the development of a carbon nanotube template method for large-scale synthesis of SiC NW combing with in situ characterization of SiC NW during growth and post-mortem. Design of an economically viable device is envisaged to exploit the in house generated SiC NWs. By introducing novel multiple sample holders for atmospheric gaseous reaction, the designed device can enable efficient catalyst/reactant contact along the vertically orientation of SiC NW and reduce the cost for the device by at least a half.The SOLARFUELS is built across research areas of materials science, chemistry, chemical and device engineering. It perfectly integrates the Experienced Researcher (ER)\u2019s skills in solar energy application/device development and the Supervisor\u2019s expertise in nanomaterials synthesis/characterization. It will play an important role in advancing ER's career for a permanent position and in addition it will contribute to new approaches to further host's solar fuel research.", "To": ["2017-08-27, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-08-28"], "Project_ID": ["654723"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Utilizing the fusion machinery of Herpes Simplex Virus to unveil the general process of membrane fusion"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["KGBVIFEF"], "Technology_Description": "Membrane fusion is a basic cell biological process found in diverse pathways ranging from vesicle trafficking and cell division to viral host entry. It is mediated by fusion proteins residing in the membrane. The underlying molecular mechanisms are supposed to follow a common order of events, i.e. fusion through hemifusion. Cell entry of Herpes simplex virus-1 (HSV-1) is enabled by glycoproteins residing on the viral envelope membrane. In contrast to other viruses, this is accomplished by different glycoprotein species, mediating together the attachment and subsequent fusion between the viral and host cell membrane. At least four of these proteins are essential for membrane deformation leading to fusion pore formation. In the here proposed project, I will take advantage of the modularity of the HSV-1 fusion machinery to dissect this process into discrete steps which I will analyse in situ at molecular resolution to determine the molecular details of membrane fusion. To do so, I will employ a multidisciplinary approach combining methods and data from structural biology, biochemistry as well as biophysics and molecular dynamics to solve the mechanistic details of a cell biological question. This includes fluorescence and cryo electron microscopy and tomography full-length membrane glycoprotein purification and biochemical reconstitution methods, biomolecular interaction and structural X-ray analysis, sub-volume averaging and classification as well as single particle imaging. To find the nenecessary triggers for fusion I will reconstitute the complete fusion system and thereby reveal the spatio-temporal changes that catalyse the fusion process. Taken together this structure-functional study will enable insights into hitherto ill-characterised intermediates in the conserved mechanism of membrane fusion. This project is a great opportunity to expand my research competence at the interphase of different fields ranging from cellular and structural biology to biophysics.", "To": ["2017-04-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-05-01"], "Project_ID": ["654154"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["International mobility, local economics and European cooperation policies in the central Sahara"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["MOLECOPS"], "Technology_Description": "Migration by nationals of sub-Saharan countries to the Sahara, often assimilated by African and European public institutions to departures to Europe, have, over the last decade, become the object of increased surveillance. The European Union has put migration at the heart of its relations with Africa, and finances a broad range of programmes that aim at a better management of migration in the Sahara. Ranging from encouragement of legal reforms to assistance in the repatriation of migrants, via equipping border posts with sophisticated means of control, EU interventions in the area take different forms, but they all have in common that little is known of their actual impact and side-effects on the ground. The aim of this research project is to study the nature and practical results of European intervention in migration issues in the central Sahara, and its global cost, by combining an exhaustive analysis of European policies with empirical fieldwork, with a view towards understanding and correcting the representations and assumptions that underpin them. ", "To": ["2017-04-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-05-01"], "Project_ID": ["652755"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["The Fall of a Colonial Legacy: A Modern History of Syrian Borders (1920-2015)"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SYRIANBORDERS"], "Technology_Description": "This project aims to propose a contemporary history of Syrian borders from their origins (1920) to the present day (2015). Upon the completion of my fellowship, my main objective will be to publish a fully documented and innovative monograph on the history of the Syrian state by studying its emergence and consolidation, and by probing its colonial borders. As part of my research, I will rely on a multidisciplinary and comparative approach, using political science, sociology and, more generally, border studies. My innovative methodology will require me to conduct dozens of semi-structured interviews and to examine Syrian, French & British archives. ", "To": ["2018-10-09, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-10-10"], "Project_ID": ["701923"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITA CA' FOSCARI VENEZIA"], "EU_Contribution": ["EUR 180 277,20"], "Project_Title": ["Family, Power, Memory: Female Monasticism in Italy from 700 to 1100"], "Total_Cost": ["EUR 180 277,20"], "Country": ["Italy"], "Project_ACR": ["ITNUN"], "Technology_Description": "Recent history amply demonstrates the importance of religious belief as a fundamental historical force. In studying early medieval Europe, we see how crucial it has been in the creation of our own identity, underlying our belief systems, cultural assumptions and core values, as well as our institutions. Modern history and anthropology help us pose questions of immediate concern on ethnicity and nationality, women and gender, identity and belief. I have engaged with these issues previously, with a multidisciplinary mix of history, anthropology, art history and archaeology. This research project on Italian female monasteries from 700 to 1100 is also comparative and interdisciplinary. To understand medieval society, it is essential to understand monasticism, and crucial to include Italy. I propose to bring together an integrated and broad-sweeping perspective by joining these together, and to approach the study of religious women as a laboratory for exploring the complex relationship between gender and power. Royal or aristocratic monasteries have sources detailing the names, background and activities of nuns, representative of the political and ethnic composition of Italian society. To study the evolution of nunneries makes it possible to trace changes in Italian political, social and cultural patterns, with the intermingling of family and politics. Understanding the tensions between early medieval Italian society\u2019s male-controlled political and religious power, and the influence of noble women as queens and nuns, is essential for grasping women\u2019s ideological and spiritual power, and for recognizing the changing configurations of medieval Italy, a key factor for comprehending some issues still at stake in Italian society today. Generally, a study of key mechanisms concerning the relationship between women, religious belief and behaviour, and politics and society can, through comprehending these in the past, illuminate key aspects of modern European societies.", "To": ["2017-09-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["654889"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Incorporation of unnatural fluorinated amino acids to probe the function of the bacterial efflux system Kef in a cellular setting."], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["FLUOROKEF"], "Technology_Description": "The potassium efflux system, Kef, protects bacteria against the detrimental effects of electrophilic compounds via acidification of the cytoplasm. Its vital role in maintaining cell homeostasis makes Kef a promising target for antibiotics, but such drugs can be developed only with a molecular understanding of Kef activation. Our work indicates that phenylalanine residue 441 (F441) in Escherichia coli is crucial for the activation of K+ efflux. This mechanism is conserved, and F448 of Shewanella denitrificans Kef (SdKef) has the same function. This work employed X-ray crystallographic studies using a truncated construct of the E. coli Kef soluble C-terminal domain (EcKefCTD) and biophysical studies conducted on the SdKef C-terminal domain (SdKefCTD). While the crystallographic studies have been essential in hypothesis generation, they lack the dynamic aspect that is required to understand the mechanism of Kef activation. Although the use of a truncated construct has allowed development of biophysical assays, we wish to extend our work to focus on the full-length channel. To achieve these aims we will employ whole cell 19F NMR to probe the function of Kef.", "To": ["2017-09-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["660156"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Comprehensive identification of host factors involved in the early steps of HIV infection."], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["hRBP-virion"], "Technology_Description": "35 million people are currently infected with Human immunodeficiency virus (HIV), causative agent of AIDS. While cocktails of anti-retrovirals can reduce viral loading to undetectable levels, drug resistance can emerge due to the high-mutation rate of the virus. Moreover, no cure is yet achieved. Therefore, it is crucial to explore complementary therapeutic strategies, a challenge that H2020 prioritizes in health. The strict dependency of HIV on host RNA-binding proteins (RBPs) represents a potential step for intervention through host-based therapies, which can be more refractory to the evolution of resistance. In some sporadic cases, host RBPs have been shown to be incorporated into virions and impact downstream early steps of infection. However, no global and systematic studies aimed to determine the scope and biological significance of host RBPs selectively packed with the HIV RNA within the virions have been reported so far. The main goal of this action, referred to as hRBP-virion, is to address this important biological question by developing an unprecedented multidisciplinary approach that combines molecular biology and virology methods with next generation proteomics and data analysis. Hence, this pioneer approach will open new avenues of research in the field of viruses that have major health and socioeconomic impact and will enhance world-class basic and applied European innovation. The hRBP-virion project requires an exclusive mix of competences. I will bring research experience in RNA and molecular virology. My supervisor will train me in cutting-edge, system-wide proteomic methods. The host institution will provide state-of-the-art facilities and pooled expertise in a broad range of disciplines. Together these will create an excellent and unique cross-disciplinary atmosphere that will ensure the successful outcome of hRBP-virion and the appropriate transfer of knowledge among the participants.", "To": ["2019-05-02, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-03"], "Project_ID": ["700184"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Studying Interfacial Dynamics by Interferometric Scattering"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["INTFACDYN"], "Technology_Description": "We propose to apply a cutting-edge optical microscopy based on interferometric scattering microscopy (iSCAT) to directly study the dynamics of the fundamental system of nanoparticles at fluid interfaces. Nanoparticles at interfaces are a central research topic in colloidal science. They have various technological applications, related to, for example, emulsification, optical devices, and chemical catalysis. In addition, nanoparticles at interfaces make an ideal experimental model system for investigating topics in condensed matter physics, such as the dynamics of partially confined fluids and the phase behavior of 2D fluids. While many experimental studies have characterized the self-assembly, structure, and motion of such particles, important questions relating to adsorption/desorption dynamics and inertial effects, remain unanswered due to technical limitations of temporal and spatial resolution. iSCAT offers exclusive accessibility to answer these questions, through unprecedented capabilities of nanoparticle tracking in three dimensions with simultaneous nanometre spatial and microsecond temporal precision. Specifically, we aim at achieving two objectives for the first time; (i) observing and quantifying inertial effects at fluid-fluid interfaces, and (ii) characterizing the three-dimensional interfacial behavior of nanoparticles at interfaces. Overall, these objectives aim at expanding and generalising interfacial microrheology to much shorter time-scales, as well as to provide critical insight to the mechanisms underlying particle stability and self-assembly at interfaces.", "To": ["2018-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["706461"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Discovering the signalling pathways and physiology of active rhomboid proteases in the brain"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["NeuroRhomboid"], "Technology_Description": "Proteases control major pathways in the nervous system and aberrant proteolysis underlies many neurobiological disorders and diseases e.g. Alzheimer's and Parkinson's disease. Signal generation and release is tightly regulated by protease activity, as many key signalling factors are synthesised as transmembrane precursors that require cleavage to liberate their active ectodomains. The largest family of intramembrane proteases are the newly discovered rhomboids, which are found in all kingdoms of life. To date, their physiological significance in mammals is largely unknown, as is the substrate-selectivity of most mammalian rhomboids. I have exciting preliminary data that two uncharacterised mammalian rhomboids, RHBDL1 and RHBDL3, are specifically highly expressed in primary neurons in the CNS. Unlike the well-studied RHBDL2 and Drosophila rhomboids 1-3, they do not have activity against EGF-like growth factors, so they are likely to cleave a novel substrate. A major limitation in protease research has been the lack of unbiased and systematic screens for their substrates. Addressing this deficiency, first, I aim to identify RHBDL1/3-dependent substrates in primary neurons, by adapting recently developed biochemical assays, such as SPECS and BioID. My second aim is the mechanistic validation of these substrates. Third, I will be the first to study the physiological role for active rhomboids, using CRISPR-mediated knock-out neurons and mice. By discovering the role and function of RHBDL1/3 in the brain, I will make an important contribution towards the elucidation of the physiological and medical significance of rhomboid proteases in mammals.", "To": ["2017-04-06, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-04-07"], "Project_ID": ["659166"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["The psychology of inequality: Understanding the social, cognitive and motivational foundations of people's attitudes towards the distribution of power and resources in society."], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["PINQ"], "Technology_Description": "The annual meeting of the World Economic Forum (WEF) in Davos, 2015, identified deepening inequality as the most pressing challenge facing the world. High inequality is liked to numerous social problems, as well as to greater economic instability. Concern for these problems is not only restricted to highly educated, socio-political elites (e.g. the WEF). Large-scale surveys in several countries have shown that people generally have a preference for greater equality. However, despite broadly shared egalitarian ideals, people often oppose policies aimed at reducing inequality and support policies that would have the opposite effect. I will call this the principle-implementation gap in attitudes towards inequality. The primary aim of this project is to understand the reasons for this gap, by applying knowledge from social psychology to current work on inequality from the disciplines of economics, political science and sociology. In particular, I will test whether similar social constraints, cognitive biases and psychological motives that explain other inconsistencies between peoples ideals and their attitudes, can also be used to explain this particular principle-implementation gap. I will draw on methods used across the social sciences, including longitudinal and multilevel modelling of large-scale, cross-national survey data, and carefully controlled laboratory experiments. This multidisciplinary endeavour will provide insights to policy makers, advocates and educators about how to communicate the problem of inequality to the general public in a way that maximises awareness and engagement. These insights will also be applicable to understanding what drives public opinion on other, similarly complex issues of resource distribution that face modern societies (e.g. international trade). Thus, this project will shed light on how some of the biggest global issues of our time can be addressed through the democratic process.", "To": ["2019-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-02-01"], "Project_ID": ["703316"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 1 758 846"], "Project_Title": ["Chemical biology approaches to unraveling the histone code"], "Total_Cost": ["EUR 1 758 846"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["EPITOOLS"], "Technology_Description": "Posttranslational modifications on histones play crucial roles in the epigenetic regulation of eukaryotic gene expression. Chemical modifications that occur on histone tails include acetylation, methylation, phosphorylation, ubiquitination, and SUMOylation. This chemical diversity together with the positions and combinations of these modifications give rise to complex networks of highly controlled gene expression programs. The identification and characterisation of chromatin-associated proteins (or epigenetic regulators) in recent years has advanced our understanding of the significance of these histone modifications and the regulatory outcomes in development and in disease. ", "To": ["2021-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-04-01"], "Project_ID": ["679479"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 1 497 422"], "Project_Title": ["Low-dimensional topology in Oxford"], "Total_Cost": ["EUR 1 497 422"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["OXTOP"], "Technology_Description": "This project aims to build a group that brings together experts in gauge-theoretic, geometric, and group-theoretic techniques. It consists of 4 branches. ", "To": ["2021-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["674978"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 1 361 077"], "Project_Title": ["Geometry and Anomalous Dynamic Growth of Elastic instabiliTies"], "Total_Cost": ["EUR 1 361 077"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["GADGET"], "Technology_Description": "Elastic instabilities are ubiquitous, from the wrinkles that form on skin to the \u2018snap-through\u2019 of an umbrella on a windy day. The complex patterns such instabilities make, and the great speed with which they develop, have led to a host of technological and scientific applications. However, recent experiments have revealed significant gaps in our theoretical understanding of such instabilities, particularly in the roles played by geometry and dynamics. I will establish a group to develop and validate a theoretical framework within which these results can be understood. Central to my approach is an appreciation of the crucial role of geometry in the pattern formation and dynamics of elastic instabilities.", "To": ["2020-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-04-01"], "Project_ID": ["637334"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Assessment of Global and Regional Cardiac Functional Improvements in a Murine Model of Myocardial Infarction following Stem Cell Treatments"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["STEMCELLTRACK"], "Technology_Description": "Cardiosphere-derived stem cell (CDC) therapy for myocardial infarction (MI) has been shown to elicit moderate beneficial effects. Research currently focuses on improving CDC administration, retention and efficacy. This proposal aims to develop Magnetic Resonance Imaging (MRI) and engineering tools to facilitate this research. Specifically, microinjection of fluorine-19 labeled CDCs will allow for MRI tracking and quantification in vivo. Non-invasive global and regional cardiac function measurements will assess efficacy of stem cell (SC) therapy. Parallel to these studies will be an independent design, synthesis, use and evaluation of fiber-enriched scaffold. The anticipated impact will be multifaceted, including the study of cardiac function in disease, and the potential applicability of generated results with cutting edge SC regenerative technologies in heart failure and prominent cardiomyopathies. Research efforts will be stimulated in manufacturing processes for scaffolds, cardiac functional assessment post-injection of SCs, and validation of their homing, engraftment and viability using cellular tracking methods.", "To": ["2017-06-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-07-01"], "Project_ID": ["652986"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 1 499 496"], "Project_Title": ["Terrestrial vertebrates and the evolutionary origins of morphological diversity"], "Total_Cost": ["EUR 1 499 496"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["TEMPO"], "Technology_Description": "Explaining the great disparity of organismal form is a central goal of biological research. However, despite many decades of inquiry, there is little understanding of how evolution gave rise to this disparity. Key hypotheses predict changes in macroevolutionary modes through geological time: rates of evolution may either have decreased as global niche space became crowded, or increased due to accumulation of key innovations that improve body plan versatility. The absence of data to test these hypotheses a major knowledge gap that severely limits our understanding of evolution on Earth.", "To": ["2021-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["677774"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 168 166,90"], "Project_Title": ["Probabilistic Argumentation on the Web"], "Total_Cost": ["EUR 168 166,90"], "Country": ["United Kingdom"], "Project_ACR": ["ARGUE_WEB"], "Technology_Description": "The (World Wide) Web hosts a wide range of argumentative text from resources of multiple disciplines and online debates. Also, tools (such as Debadepedia and Twitter) encourage the communication of arguments in social and scientific settings. With the exponential growth of the Web and its users, a vast amount of argumentative text on the Web remains hidden. In order to query the Web for structured arguments included in web pages, it is necessary to address both of the following issues: (1) the deployment of technologies that enable an automatic extraction of the components of natural language arguments and the representation of their meaning and (2) the deployment of a pragmatic argumentation formalism that takes into account the uncertain and inconsistent nature of data on the Web to reason with structured arguments. ", "To": ["2017-12-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["707407"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 1 499 911"], "Project_Title": ["Online Labour: The Construction of Labour Markets, Institutions and Movements on the Internet"], "Total_Cost": ["EUR 1 499 911"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["iLABOUR"], "Technology_Description": "\"World Bank, EC Joint Research Centre, and other bodies have recently highlighted the potential of online labour markets to boost employment and economic growth. While national job markets have stagnated, online labour markets that connect firms with knowledge and service workers around the world have grown up to 60% a year.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["639652"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 1 727 456"], "Project_Title": ["Molecular analysis of the Hedgehog signal transduction complex in the primary cilium"], "Total_Cost": ["EUR 1 727 456"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["CilDyn"], "Technology_Description": "The unexpected connection between the primary cilium and cell-to-cell signalling is one of the most exciting discoveries in cell and developmental biology in the last decade. In particular, the Hedgehog (Hh) pathway relies on the primary cilium to fulfil its fundamental functions in orchestrating vertebrate development. This microtubule-based antenna, up to 5 \u00b5m long, protrudes from the plasma membrane of almost every human cell and is the essential compartment for the entire Hh signalling cascade. All its molecular components, from the most upstream transmembrane Hh receptor down to the ultimate transcription factors, are dynamically localised and enriched in the primary cilium. The aim of this proposal, which combines structural biology and live cell imaging, is to understand the function and signalling consequences of the multivalent interactions between Hh signal transducer proteins as well as their spatial and temporal regulation in the primary cilium. The key questions my laboratory will address are: What are the rules for assembly of Hh signal transduction complexes? How dynamic are these complexes in size and organisation? How are these processes linked to the transport and accumulation in the primary cilium?", "To": ["2020-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-08-01"], "Project_ID": ["647278"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["UNIVERSITY OF LONDON", "UNIVERSITY OF LONDON", "CITY UNIVERSITY OF LONDON", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 1 955 270"], "Project_Title": ["Metacognition of Concepts"], "Total_Cost": ["EUR 1 955 270"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom", "United Kingdom"], "Project_ACR": ["MetCogCon"], "Technology_Description": "This project will investigate the thoughts and feelings that accompany the use of concepts. Concepts lie at the heart of the extraordinary power of the human mind. They are the building blocks of thought, the tools with which we think. Like physical tools, they can be more or less dependable, more or less fit for purpose: e.g. for most people GENE feels like a better concept than MEME. We have an intuitive sense of how dependable a concept is, which is crucial when we decide whether to rely on the concept. It can underpin our decision to reject some concepts (e.g. RACE) and embrace others in our theorising (e.g SPECIES). Similarly in everyday thinking: when concepts are selected for reasoning and induction, and when different cognitive processes compete for control of action, the metacognition that accompanies the concepts involved will have a powerful effect. However, metacognition directed at concepts is still poorly understood. We lack even a clear theoretical framework to underpin research in this area.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["681422"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 1 929 306"], "Project_Title": ["Cities in Global Financial Networks: Financial and Business Services and Developmentin the 21st Century"], "Total_Cost": ["EUR 1 929 306"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["CityNet"], "Technology_Description": "Financial and business services (FABS), including law, accounting, and business consulting, have been one of the most dynamic sectors of the world economy, with a fivefold rise in real value added since 1980. Although FABS are central to the processes of globalisation, financialisation, urbanisation and development, our understanding of the sector in the context of tumultuous changes of the early 21st century is partial. How have the FABS firms and centres been affected by the global financial crisis and the Eurozone crisis? How are they changing in response to new financial regulation, the expected shift of economic activity to the Asia-Pacific region, and the digital revolution? What are the impacts of FABS on urban, regional, and global development? We urgently need groundbreaking frontier research to better understand the nature and dynamics of FABS, and their implications.", "To": ["2021-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-08-01"], "Project_ID": ["681337"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 1 106 719"], "Project_Title": ["Randomness and pseudorandomness in discrete mathematics"], "Total_Cost": ["EUR 1 106 719"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["RanDM"], "Technology_Description": "Discrete mathematics has seen enormous advances in the last few years, with solutions being found to a number of famous and long-standing questions, such as the Erdos distinct distance problem and the existence conjecture for combinatorial designs. Much of this progress owes to an increased understanding of random and pseudorandom objects. An entire framework, known as the probabilistic method, has grown around the application of randomness to combinatorial problems, while pseudorandomness is playing an increasingly important role.", "To": ["2021-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-07-01"], "Project_ID": ["676632"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Enantioselective Synthesis of Madangamine Alkaloids via Organocatalytic Desymmetrization"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ESOMAVOD"], "Technology_Description": "This project will develop a new, highly enantioselective, state-of-the-art synthetic route to madangamine alkaloids B, C and E based on a novel organocatalytic desymmetrization reaction as a key step, which will allow the rapid and efficient construction of the AC rings ready for subsequent advancement to the majority of the family members. Evaluation of the anti-cancer biological activity of the different madangamines and late stage intermediates will be carried out. This Fellowship project combines total synthesis, new asymmetric methodology development via organocatalysis and biological evaluation. This multidisciplinary Fellowship, based on high-quality and novel research at the University of Oxford, one of the top-research centres worldwide, has been designed to augment and complement Dr Vasu\u2019s skills and knowledge to improve his career possibilities and, at the same time, Dr Vasu\u2019s experience in new methodology development and catalysed transformations will be advantageous to the design of the organocatalyst in the key step of the synthesis. The Fellowship will also be useful to establish new collaboration opportunities for the Dixon group. Through the training and the research results arising, the Fellowship will be beneficial to the fellow, the host institution and European science.", "To": ["2018-08-15, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-08-16"], "Project_ID": ["703789"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 1 902 598"], "Project_Title": ["Family size matters: How low fertility affects the (re)production of social inequalities"], "Total_Cost": ["EUR 1 902 598"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["FAMSIZEMATTERS"], "Technology_Description": "This is the first comprehensive study on the consequences of low fertility for the (re)production of social inequalities. Inequalities in socio-economic well-being, including gender inequalities and regional inequalities, are reproduced from generation to generation. The family plays a central role in the reproduction of social inequalities. Over the last 5 decades, most societies in Europe and East-Asia moved or started moving towards low fertility regimes where the majority of women bear 0, 1 or 2 children. What does this radical change in family size imply for the (re)production of social inequalities? ", "To": ["2021-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-07-01"], "Project_ID": ["681546"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 2 492 266"], "Project_Title": ["Vision-based Guidance and Control in Birds, with Applications to Autonomous Unmanned Aircraft"], "Total_Cost": ["EUR 2 492 266"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["HawkEye"], "Technology_Description": "Birds have been called \u201cune aile guide\u0301e par un oeil\u201d, and whilst they possess many senses besides vision, their wings are indeed guided largely by their eyes. Nevertheless, we know surprisingly little of how birds use vision to guide their flight, and almost nothing of the underlying guidance and control laws. This is an extraordinary omission, and unfortunate given the importance that vision is poised to assume in autonomous unmanned aircraft. With good reason, the law still requires a human eye to remain in the loop, but as with the coming revolution in driverless cars, the future of flight lies in autonomy. I see a once-in-a-career opportunity here: we need only imagine a hawk, shooting over the top of a hedgerow then plunging through the undergrowth onto its fleeting prey, to see what engineering could learn. Building upon the success of my ERC Starting Grant on Bird and Insect Flight Dynamics and Control, my proposed Consolidator Grant has two overarching ambitions: 1) to revolutionize our understanding of vision-based guidance and control in birds; and 2) to carry these insights over to application in unmanned autonomous aircraft. This presents a formidable technical challenge, but by combining a state-of-the-art motion capture suite with targets/obstacles moving under motion control in a custom-built facility, I will use system identification techniques to unambiguously identify the guidance and control laws underpinning perching, pursuit, obstacle avoidance, and gap negotiation in birds. More than this, I will identify the precise motion cues to which they attend, settling longstanding questions on the extent to which guidance emerges from simple algorithmic rules versus state feedback and estimation, with wider implications for our understanding of avian perception. This work will break new ground in all directions, testing applied insights in the same facility, and so leading the world in drawing the study of birds and aircraft together under one roof.", "To": ["2021-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-08-01"], "Project_ID": ["682501"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 2 605 261"], "Project_Title": ["Resolving Morpho-Phonological Alternation: Historical, Neurolinguistic, and Computational Approaches"], "Total_Cost": ["EUR 2 605 261"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["MOR-PHON"], "Technology_Description": "In morpho-phonological alternations the shapes of morphemes differ between morphologically related word forms. In these alternations the morphological environment is also implicated (rev\u00e9re ~ r\u00e9verence verb [i\u02d0] ~ noun [\u025b] and stress differ) unlike alternations which are conditioned only by the phonological environment.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["695481"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 1 980 112"], "Project_Title": ["Computational Propaganda:Investigating the Impact of Algorithms and Bots on Political Discourse in Europe"], "Total_Cost": ["EUR 1 980 112"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["COMPROP"], "Technology_Description": "Social media can have an impressive impact on civic engagement and political discourse. Yet increasingly we find political actors using digital media and automated scripts for social control. Computational propaganda\u2014through bots, botnets, and algorithms\u2014has become one of the most concerning impacts of technology innovation. Unfortunately, bot identification and impact analysis are among the most difficult research challenges facing the social and computer sciences.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["648311"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 1 482 363"], "Project_Title": ["Characterising the Gene Regulatory Networks Governing Photosynthesis: From Basic Understanding to Targeted Engineering"], "Total_Cost": ["EUR 1 482 363"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["PHOTONET-C4"], "Technology_Description": "Photosynthesis underpins life on earth. Despite its fundamental importance, our knowledge of the molecular regulators that control the expression of photosynthetic genes is limited, and only four transcription factors are known to regulate the expression of cohorts of photosynthetic genes in plants. ", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-11-01"], "Project_ID": ["637765"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 1 438 846"], "Project_Title": ["Dynamic Earth Evolution and Paleogeography through Tomographic Imaging of the Mantle"], "Total_Cost": ["EUR 1 438 846"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["DEEP TIME"], "Technology_Description": "DEEP TIME will unearth a record of geological time that is buried thousands of kilometres deep. The seafloor that covers two-thirds of the earth's surface is a tiny fraction of all seafloor created during its history \u2013 the rest has sunk back into the viscous mantle. Slabs of subducted seafloor carry a record of surface history: how continents and oceans were configured over time and where their tectonic plate boundaries lay. DEEP TIME will follow former surface oceans as far back in time as the convecting mantle system will permit, by imaging subducted slabs down to the core with cutting-edge seismological techniques. Current tectonic plate reconstructions incorporate little if any of this deep structural information, which probably reaches back 300+ million years; they are based on present-day seafloor, which constrains only the past 100-150 million years.", "To": ["2020-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-08-01"], "Project_ID": ["639003"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 1 999 416"], "Project_Title": ["Discovering how polycomb domains form and function in gene regulation"], "Total_Cost": ["EUR 1 999 416"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["PolyDomFormFuncReg"], "Technology_Description": "Polycomb group chromatin modifying systems are essential for normal gene regulation and development, and alterations in their activity are a hallmark of a broad range of cancers. Although the chromatin modifications placed by the two central polycomb protein complexes (PRC1 and PRC2) are well-characterized, how this fascinating system selects its target sites in vivo, and then forms polycomb chromatin domains that are repressive to transcription remains enigmatic. This constitutes the major conceptual gap in our understanding of this essential gene regulatory system. We recently discovered a new pathway that is sufficient in model systems to initiate polycomb chromatin domain formation. Building on this discovery, an ambitious high-risk/high-reward yet hypothesis-driven multidisciplinary approach integrating biochemical, molecular, genomic, and single-cell analyses will be exploited to discover the fundamental principles that underpin polycomb domain formation and subsequently transcriptional repression. Specifically, the three aims of the research programme are to: (i) Discover how the KDM2B/PRC1 complex initiates polycomb domain formation, (ii) Discover how polycomb target sites are selected and polycomb domains formed during normal cell lineage commitment, and (iii) Discover how polycomb domains regulate gene expression. Going well beyond the state-of-the-art, our innovative approaches will lead to major new breakthroughs closing the conceptual gap that currently limits our understanding of how polycomb complexes regulate gene expression, an essential first step towards the possibility of devising strategies for therapeutic intervention in human cancers and other diseases where these systems are perturbed. Furthermore, support from the ERC in tackling these important problems will allow me to recruit the talented individuals necessary to achieve our objectives and consolidate my position as an emerging leader in the field.", "To": ["2021-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["681440"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 3 234 789"], "Project_Title": ["Adaptive Optical Microscopy Systems: Unifying theory, practice and applications"], "Total_Cost": ["EUR 3 234 789"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["AdOMiS"], "Technology_Description": "Recent technological advances in optical microscopy have vastly broadened the possibilities for applications in the biomedical sciences. Fluorescence microscopy is the central tool for investigation of molecular structures and dynamics that take place in the cellular and tissue environment. Coupled with progress in labeling methods, these microscopes permit observation of biological structures and processes with unprecedented sensitivity and resolution. This work has been enabled by the engineering development of diverse optical systems that provide different capabilities for the imaging toolkit. All such methods rely upon high fidelity optics to provide optimal resolution and efficiency, but they all suffer from aberrations caused by refractive index variations within the specimen. It is widely accepted that in many applications this fundamental problem prevents optimum operation and limits capability. Adaptive optics (AO) has been introduced to overcome these limitations by correcting aberrations and a range of demonstrations has shown clearly its potential. Indeed, it shows great promise to improve virtually all types of research or commercial microscopes, but significant challenges must still be met before AO can be widely implemented in routine imaging. Current advances are being made through development of bespoke AO solutions to individual imaging tasks. However, the diversity of microscopy methods means that individual solutions are often not translatable to other systems. This proposal is directed towards the creation of theoretical and practical frameworks that tie together AO concepts and provide a suite of scientific tools with broad application. This will be achieved through a systems approach that encompasses theoretical modelling, optical engineering and the requirements of biological applications. Additional outputs will include practical designs, operating protocols and software algorithms that will support next generation AO microscope systems.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["695140"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 2 863 366"], "Project_Title": ["Large Scale Structure Constraints of General Relativity"], "Total_Cost": ["EUR 2 863 366"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["GravityLS"], "Technology_Description": "The past decade has witnessed a phenomenal success in relativistic cosmology. It is now possible to constrain the structure, content and evolution of the Universe with an accuracy of a few percent. The current focus of cosmology is to understand some of the fundamental problems in physics such as: the accelerated expansion of the universe, the nature of dark energy and dark matter and the initial conditions of large scale structure. Key to addressing these problems is ascertaining the role general relativity plays in cosmology. While we now have remarkable astrophysical constraints on general relativity on milliparsec scales, we have no direct cosmological constraints on gigaparsec scales. Given the quality of the up and coming cosmological data, it is now time to tackle the challenge of constraining general relativity on large scales.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["693024"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["UNIVERSITA COMMERCIALE LUIGI BOCCONI", "UNIVERSITA COMMERCIALE LUIGI BOCCONI", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 2 400 555"], "Project_Title": ["Discontinuities in Household and Family Formation"], "Total_Cost": ["EUR 2 400 555"], "Country": ["Italy", "Italy", "United Kingdom"], "Project_ACR": ["DisCont"], "Technology_Description": "Household, family and fertility changes are key drivers of population dynamics. Discovering and explaining the velocity of these changes is essential to understand the current situation and to provide scientific evidence on our demographic future. DisCont will provide seminal contributions by studying the impact of macro-level discontinuities on household and family formation (including fertility) in post-industrial contemporary societies. In the past decade, two macro-level discontinuities have radically transformed lives: the Great Recession and the digitalization of life and of the life course. Although their short-term and long-term impacts are likely to be fundamental, they have not yet been systematically analysed. Through a coordinated series of theoretically-founded empirical studies based on linked macro- and micro-level data, and using a comparative perspective, DisCont will argue that macro-level discontinuities are crucial in explaining broad changes in household and family formation, and that their effects can be persistent either for the population as a whole, or for specific cohorts. DisCont will contribute to five areas: 1) it will make theoretical advances by showing the importance of macro-level discontinuities in the explanation of changes in household and family formation in particular, and in population dynamics in general; 2) it will substantially advance our knowledge of household and family formation in post-industrial contemporary societies; 3) it will contribute in a systematic and path-breaking way to research on the broader societal impact of digitalization and of the Great Recession; 4) it will bring a paradigm shift in Age-Period-Cohort modelling; 5) it will make ground-breaking contributions on the demographic use of \u201cbig data\u201d and on the use of agent-based models for the population-level implications of household and family change.", "To": ["2022-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-02-01"], "Project_ID": ["694262"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "UNIVERSITEIT UTRECHT"], "EU_Contribution": ["EUR 2 186 400"], "Project_Title": ["Music and Late Medieval European Court Cultures: Towards a Trans-Disciplinary and Post-National Cultural Poetics of the Performative Arts"], "Total_Cost": ["EUR 2 186 400"], "Country": ["United Kingdom", "United Kingdom", "Netherlands"], "Project_ACR": ["MALMECC"], "Technology_Description": "Late medieval European court cultures have traditionally been studied from a mono-disciplinary and national(ist) perspective. This focus has obscured much of the interplay of cultural performances that informed \u201ccourtly life\u201d. Recent research has begun to reverse this, focusing on issues such as the tensions between orality, writing, and performance; the sociocultural dimensions of making and owning manuscripts (musical and otherwise); the interstices between musical, literary and visual texts and political, social and religious rituals; and the impact of gender, kinship, and social status on the genesis and transmission of culture and music. These \u201cnew medievalist\u201d studies have significantly enhanced our understanding of the cultural meanings of singing, listening, and sound in late medieval times. ", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["669190"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 2 350 533"], "Project_Title": ["Monumental Art of the Christian and Early Islamic East: Cultural Identities and Classical Heritage"], "Total_Cost": ["EUR 2 350 533"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["HERITAGE"], "Technology_Description": "This project will analyse the monumental art (large decorative programmes on buildings) of two areas of the former eastern Roman Empire which came under Islamic rule but which have never been the subject of an integrated comprehensive study: Egypt and Syro-Palestine (modern Syria, Jordan, Lebanon, and Israel/Palestine). It aims to determine systematically how the strength and nature of the local \u2018classical\u2019 (Greco-Roman) traditions and expressions of identities influenced monumental art in these regions during Late Antiquity (AD 250\u2013750), the period of transition from paganism to Christianity and, in turn, to Islam. By defining and distinguishing between the different strands of classical influence, both local and external (from the centres of Rome, Constantinople, and Alexandria), and investigating the roles of local artists and artisans as creators rather than imitators, this project will transform our understanding of the artistic culture of the late antique Middle East.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["694105"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["The Colours of the Past in Victorian England"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["COPAST"], "Technology_Description": "This project entitled \u201cThe Colours of the Past in Victorian England\u201d (COPAST) aims to analyse the reception of the chromatic material culture of Antiquity and the Middle Ages in the works of writers and painters from William Morris\u2019s close circle. These politically-committed poets and artists looked towards the ideologically-charged colours of Hellenic and medieval arts and crafts, in order to retrieve and emulate supposedly more meaningful hues and dyeing processes which they believed modern science and economic imperatives had stripped of their symbolic and artistic value. The Victorian age (1837-1901) was indeed a turning point in terms of scientific discoveries of new chemical colours, including coal-tar based synthetic dyes. Dr. Ribeyrol will investigate ideological approaches to ancient polychromy in the context of the Greek and Gothic Revivals which affected industrialized England in the second half of the 19th century. Using close analysis of art works, literary texts and pigment recipe books, she will contrast these ancient hues with the new chemical aniline dyes which were mainly devised for the expanding textile industry. This innovative focus on chromatic materiality in the field of Victorian art history and literature will enable her to shed light on the artistic impact of this colour revolution which radically unsettled the way certain avant-garde Victorian writers and artists related to chromatic terminology and used traditional, organic pigments.", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["655396"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 1 312 383"], "Project_Title": ["New Approaches to the Identification of Macroeconomic Models"], "Total_Cost": ["EUR 1 312 383"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["Macro Identification"], "Technology_Description": "Macroeconomic data are largely non-experimental. Thus, causal inference in macroeconomics is largely based on assumptions about what aspects of the variation in the data are exogenous. This presents two major challenges, which this research addresses directly. First, few such assumptions are generally accepted. Second, conditional on any set of assumptions, identification of causal effects is often weak because there is little relevant variation in the data. To tackle these challenges, I propose three lines of enquiry to explore new sources of identification and develop the requisite econometric methods.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["647152"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 2 278 073"], "Project_Title": ["Autocatalysis: A bottom-up approach to understanding the origins of life"], "Total_Cost": ["EUR 2 278 073"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["Autocat"], "Technology_Description": "\"The origin of life is not well understood, and is one of the great remaining questions in science. Autocatalytic chemical reactions have been extensively studied with the aim of providing insight into the principles underlying living systems. In biology, organisms can be thought of as imperfect self-replicators, which produce closely related species, allowing for selection and evolution. Autocatalysis is also an important part of many other biological processes. ", "To": ["2021-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["681491"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 1 492 828"], "Project_Title": ["External Control of Liquid Nanofilms for Switchable Friction and Adhesion"], "Total_Cost": ["EUR 1 492 828"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["LIQUISWITCH"], "Technology_Description": "The overall vision of the project is to demonstrate methods for switching friction and adhesion \u2013 such as \u201cswitch off friction\u201d or \u201cswitch on adhesion\u201d \u2013 reversibly and with remote control. My hypothesis is that fluids confined to nanofilms between solid objects can be designed to dramatically alter their surface properties under the influence of applied fields, and so can be used to switch friction, lubrication or adhesion in a controlled and reversible way. The emphasis of the project is on creating well-defined model experiments, with high resolution in both film thickness and interaction forces, in order to reach a fundamental understanding of the new concepts and mechanisms involved. The novelty lies in both the newly-proposed mechanisms of switching friction and adhesion interactions, and the new instrumentation constructed to detect and analyse the forces. The new methodologies necessary for these pioneering experiments involve two new versions of a Surface Force Balance (SFB) providing molecular-resolution (0.1nm) control and measurement of interfacial liquid films, controlled application of electric and magnetic fields, and ultra-sensitive measurement of friction and adhesion. Notably, one of these new instruments will have macroscopic graphene electrodes for confinement of liquid nanofilms (0 \u2013 100nm) between atomically smooth electrodes. The wide range of \u2018switchable\u2019 liquids studied will include polyelectrolytes, magnetic fluids, ionic liquids and self-assembled systems. Ultimately, this project will change the way we think about surface interactions into something we can \u2018switch and control\u2019.", "To": ["2021-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-04-01"], "Project_ID": ["676861"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 2 066 976"], "Project_Title": ["Uncertainty and Precaution: Environmental Decisions Involving Catastrophic Threats"], "Total_Cost": ["EUR 2 066 976"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["UnPrEDICT"], "Technology_Description": "The goal of this project is to supplement or replace the precautionary principle with decision guidance that better handles both normative and empirical uncertainty in contexts of speculative but potentially catastrophic consequences. It has been claimed that emerging technologies such as geoengineering, biotechnology, or machine intelligence could have catastrophic impacts on human civilization or the biosphere, indicating the need for precaution until scientific uncertainty has been resolved. Yet it is unclear how to apply the precautionary principle to cases where the deeper investigations of scientific uncertainties that it calls for can themselves be a source of catastrophic risk (in e.g. gain-of-function research and geoengineering experiments). Furthermore, the precautionary principle fails to account for moral uncertainty \u2014even though many decisions depend more sensitively on ethical parameters (e.g. our obligations to future generations, discount rates, intrinsic value of nature) than on remaining scientific uncertainties.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["669751"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "KING'S COLLEGE LONDON"], "EU_Contribution": ["EUR 1 794 562"], "Project_Title": ["Higgs bundles: Supersymmetric Gauge Theories and Geometry"], "Total_Cost": ["EUR 1 794 562"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom"], "Project_ACR": ["HIGGSBNDL"], "Technology_Description": "String theory provides a unified description of particle physics and gravity, within a consistent theory of quantum gravity. The goal of this research is to develop both the phenomenological implications as well as conceptual foundations of string theory and its non-perturbative completions, M- and F-theory. Both, seemingly independent, questions are deeply connected to a mathematical structure, the Higgs bundle, which characterizes supersymmetric vacua of dimensionally reduced gauge theories, and insights into the moduli space of Higgs bundles will result in a fruitful cross-connection between these subjects.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["682608"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 2 497 907"], "Project_Title": ["CEREBRAL ASYMMETRY: NEW DIRECTIONS IN CORRELATES AND ETIOLOGY"], "Total_Cost": ["EUR 2 497 907"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["CANDICE"], "Technology_Description": "\"150 years after Broca's seminal statement \"Nous parlons avec l'h\u00e9misph\u00e8re gauche\" we still do not know how or why we have this bias. I propose that by studying cases of impaired language development and combining genetic and neuropsychological approaches we will be able to make a leap forward in our understanding of the quintessentially human characteristic of functional cerebral asymmetry. I argue that contradictory findings in the literature may be reconciled if we adopt a novel approach to cerebral asymmetry. In particular, I propose a network efficiency hypothesis which maintains that optimal development depends on organisation of key language functions within the same cerebral hemisphere.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["694189"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 1 980 966"], "Project_Title": ["Foundations of Factorized Data Management Systems"], "Total_Cost": ["EUR 1 980 966"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["FADAMS"], "Technology_Description": "The objective of this project is to investigate scalability questions arising with a new wave of smart relational data management systems that integrate analytics and query processing. These questions will be addressed by a fundamental shift from centralized processing on tabular data representation, as supported by traditional systems and analytics software packages, to distributed and approximate processing on factorized data representation.", "To": ["2021-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["682588"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 1 706 729"], "Project_Title": ["Combinatorial Construction"], "Total_Cost": ["EUR 1 706 729"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["CC"], "Technology_Description": "Combinatorial Construction is a mathematical challenge with many applications. Examples include the construction of networks that are very sparse but highly connected, or codes that can correct many transmission errors with little overhead in communication costs. For a general class of combinatorial objects, and some desirable property, the fundamental question in Combinatorial Construction is to demonstrate the existence of an object with the property, preferably via an explicit algorithmic construction. Thus it is ubiquitous in Computer Science, including applications to expanders, sorting networks, distributed communication, data storage, codes, cryptography and derandomisation. In popular culture it appears as the unsolved \"lottery problem\" of determining the minimum number of tickets that guarantee a prize. In a recent preprint I prove the Existence Conjecture for combinatorial designs, via a new method of Randomised Algebraic Constructions; this result has already attracted considerable attention in the mathematical community. The significance is not only in the solution of a problem posed by Steiner in 1852, but also in the discovery of a powerful new method, that promises to have many further applications in Combinatorics, and more widely in Mathematics and Theoretical Computer Science. I am now poised to resolve many other problems of combinatorial construction.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["647678"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["A Probe of the Periodic Elements for Life in the Sea"], "Total_Cost": ["EUR 2 000 000"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["APPELS"], "Technology_Description": "\"Chemical elements are the building blocks of life. The major elements, C, H. O, N, P, S are easily recognised as essential nutrients, but their use by life relies on metalloproteins. The identity of the metal centres of these metalloproteins and even the broader palette of trace elements fundamental to life are remarkably poorly known. Whole genomes remain opaque to decoding of this bioinorganic dimension, and optimal trace element concentrations for physiological function. Defining the elemental requirements for maximum growth rate of photosynthesising phytoplankton in the ocean, is critical to understanding Earth's climate. Although microscopic in stature, phytoplankton exert a gigantic influence on the biological pumping of carbon from the atmosphere to the deep ocean. Yet their metal requirements are poorly constrained, being inferred from cellular quotas and \"nutrient-like\" ocean metal distributions, susceptible to ambiguity between mistaken cellular uptake and use. ", "To": ["2021-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["681746"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 1 599 661"], "Project_Title": ["Comparing the Copperbelt: Political Culture and Knowledge Production in Central Africa"], "Total_Cost": ["EUR 1 599 661"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["ComparingCopperbelt"], "Technology_Description": "This project provides the first comparative historical analysis \u2013 local, national and transnational - of the Central African copperbelt. This globally strategic mineral region is central to the history of two nation-states (Zambia and Democratic Republic of Congo (DRC)), as well as wider debates about the role of mineral wealth in development. The project has three interrelated and comparative objectives. First, it will examine the copperbelt as a single region divided by a (post-)colonial border, across which flowed minerals, peoples, and ideas about the relationship between them. Political economy created the circumstances in which distinct political cultures of mining communities developed, but this also involved a process of imagination, drawing on \u2018modern\u2019 notions such as national development, but also morally framed ideas about the societies and land from which minerals are extracted. The project will explain the relationship between minerals and African polities, economies, societies and ideas. Second, it will analyse how \u2018top-down\u2019 knowledge production processes of Anglo-American and Belgian academies shaped understanding of these societies. Explaining how social scientists imagined and constructed copperbelt society will enable a new understanding of the relationship between mining societies and academic knowledge production. Third, it will explore the interaction between these intellectual constructions and the copperbelt\u2019s political culture, exploring the interchange between academic and popular perceptions. This project will investigate the hypothesis that the resultant understanding of this region is the result of a long unequal interaction of definition and determination between western observers and African participants that has only a partial relationship to the reality of mineral extraction, filtered as it has been through successive sedimentations of imagining and representation laid down over nearly a century of urban life in central Africa.", "To": ["2020-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-07-01"], "Project_ID": ["681657"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["UNIVERSIDADE DE AVEIRO"], "EU_Contribution": ["EUR 207 759,80"], "Project_Title": ["Thermometry and Photoacoustic-Imaging Outstanding Nanoprobes"], "Total_Cost": ["EUR 207 759,80"], "Country": ["Portugal"], "Project_ACR": ["TEMPTATION"], "Technology_Description": "This project addresses the quest of new materials and approaches that nanotechnology requires to solve the current limitations of medicine. The potential to externally track and image organs and the potential presence and evolution of diseases by using light becomes a reality thanks to the use of especially tailored biocompatible nanoplatforms. New avenues to image living bodies by light allied with mechanical waves (i.e. sound) are going to be opened. We propose here an elegant marriage between light and sound endowing smartly designed nanoprobes with the capability of deep-tissue photoacoustic imaging, also accompanied by all-optical temperature sub-tissue measuring. To increase the penetration depth and spatial resolution, an imaging approach pumping the probes with near-infrared light is proposed. Therefore, we propose a kind of material no previously exploited for photoacoustic exogenous agent, working as bimodal nanoprobe by also optically measuring temperature within the biological transparency windows in the near-infrared", "To": ["2019-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Portugal"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["709270"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["TECHNISCHE UNIVERSITEIT DELFT", "TECHNISCHE UNIVERSITEIT DELFT", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 2 479 810"], "Project_Title": ["Global Terrorism and Collective Moral Responsibility: Redesigning Military, Police and Intelligence Institutions in Liberal Democracies"], "Total_Cost": ["EUR 2 479 810"], "Country": ["Netherlands", "Netherlands", "United Kingdom"], "Project_ACR": ["GTCMR"], "Technology_Description": "International terrorism, e.g. Al Qaeda, IS, is a major global security threat. Counter-terrorism is a morally complex enterprise involving police, military, intelligence agencies and non-security agencies. Counter-terrorism should be framed as a collective moral responsibility of governments, security institutions and citizens. (1) How is international terrorism to be defined? (2) What is the required theoretical notion of collective moral responsibility? (3) What counter-terrorist strategies and tactics are effective, morally permissible and consistent with liberal democracy? Tactics: targeted killing, drone warfare, preventative detention, and bulk metadata collection (e.g. by NSA); (4) How is this inchoate collective moral responsibility to be institutionally embedded in security agencies? (i) How are security institutions to be redesigned to enable them to realise and coordinate their counter-terrorism strategies without over-reaching their various core institutional purposes which have hitherto been disparate, (e.g. law enforcement versus military combat), and without compromising human rights, (e.g. right to life of innocent civilians, right to freedom, right to privacy), including by means of morally unacceptable counter-terrorism tactics? (ii) How are these tactics to be integrated with a broad-based counter-terrorism strategy which has such measures as anti-radicalisation and state-to-state engagement to address key sources of terrorism, such as the dissemination of extremist religious ideology (e.g. militant Wahhabi ideology emanating from Saudi Arabia) and the legitimate grievances of some terrorist groups (e.g. Palestinian state)? What ought a morally permissible and efficacious (i) structure of counter-terrorist institutional arrangements, and (ii) set of counter-terrorist tactics, for a contemporary liberal democracy collaborating with other liberal democracies facing the common problem of international terrorism consist of?", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["670172"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["The molecular basis of learning and memory: uncovering the link between neuronal activation and localized translation at the synapse."], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["Syncrip_2014"], "Technology_Description": "During learning specific neuronal connections are strengthened and weakened to create long-term memory. This requires local regulation of the availability of proteins at the synapse, at a large distance from the cell body, in response to neuronal activity. It is generally recognized that such synaptic plasticity can be achieved through the regulation of translation of localized mRNAs at or near the synapses. Despite the importance of this mechanism in memory and our understanding of neurodegenerative diseases, the molecular basis by which neuronal activation regulates localised translation is still largely unknown in any system. ", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["655854"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 2 462 015"], "Project_Title": ["Perception Ultrasound by Learning Sonographic Experience"], "Total_Cost": ["EUR 2 462 015"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["PULSE"], "Technology_Description": "PULSE will develop a new generation of ultrasound imaging capabilities to revolutionize the use of this low-cost and portable imaging technology across clinical medicine worldwide. ", "To": ["2021-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-11-01"], "Project_ID": ["694581"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 1 499 985"], "Project_Title": ["Stories of Survival: Recovering the Connected Histories of Eastern Christianity in the Early Modern World"], "Total_Cost": ["EUR 1 499 985"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["SoSGlobal"], "Technology_Description": "From Lebanese immigrants in Argentina to Iraqi refugees in Sweden, Eastern Christians can be found today scattered across the entire world. Too often, however, this global migration has been seen purely as a modern development, one arising from contemporary political and confessional events in the Middle East, while in fact this phenomenon had its roots in the early modern period. From the sixteenth century onwards, Christians from the Ottoman Empire set out for distant worlds and foreign lands, travelling as far as Europe, India, Russia, and even the Americas and leaving traces of themselves across countless European and Middle Eastern archives, chanceries, and libraries. This transnational, ground-breaking project will gather all of these disparate sources into a single analytical frame to uncover, for the first time, the global and connected histories of Eastern Christianity in the early modern world. Through the work of a team of researchers under the close supervision of the PI, the project will reconstitute and analyse a \u2018lost archive\u2019 of literary, documentary, and printed sources in three continents, ten languages, and dozens of archives. Under the expert leadership of the PI, the project will include a robust strategy for dissemination, which will successfully bridge the fields of Middle Eastern, European, and global history. In doing so, this project will respond directly to one of the most pressing conceptual challenges facing global history today, that is, how to link the study of the micro-scale level of everyday life to the macro-narratives emphasised by global historians. Underlying this project, therefore, is a major intervention that seeks to advance a rigorous form of global history, and one which preserves philology and source criticism at the heart of its methodology. The outcomes of the project will include print-publications, workshops, and a searchable database of all writings by Eastern Christians from 1500 to 1750.", "To": ["2020-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-07-01"], "Project_ID": ["638578"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 2 481 744"], "Project_Title": ["Elucidating natural bilayer lipid environments"], "Total_Cost": ["EUR 2 481 744"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["ENABLE"], "Technology_Description": "Excising a membrane protein from its natural environment, preserving the lipid bilayer, and characterising the lipids that surround it is the \u2018holy grail\u2019 of membrane protein biophysics. However, with some 40,000 different lipid structures the challenges we face in understanding selective binding arise not just from the complexity and dynamics of the lipidome, but also from the transient nature of protein lipid interactions. To overcome these challenges we will take mass spectrometry (MS) into a new era, allowing, for the first time, the study of proteins in an environment as close as possible to the natural one. To do this we will (i) characterise protein lipid interactions by employing a high resolution Orbitrap mass spectrometer developed in-house, specifically for membrane proteins, (ii) capture the native lipid environment in vehicles suitable for use in conjunction with MS, and (iii) establish a new platform to be known as integral membrane protein desorption electrospray ionization (impDESI). Designed and built in-house impDESI is capable of releasing membrane proteins from surfaces directly into the mass spectrometer (MS). We will develop impDESI for membrane mimetics, and subsequently portions of natural membranes, enabling us to extract proteins with oligomeric state preserved and native lipid binding intact. The development of impDESI, in conjunction with high resolution Orbitrap MS, and coupled with the optimisation of membrane mimetics, has the potential to radically transform our understanding of native lipid binding, not only directly, but also temporally and spatially. Together these advances will answer key questions about how lipids modulate protein interfaces, occupy different binding sites, modulate membrane protein structure and modify function in vivo. Given the importance of membrane proteins as potential drugs targets understanding their modulation by lipids would be a major step towards more effective drug development.", "To": ["2021-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["695511"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "AARHUS UNIVERSITET"], "EU_Contribution": ["EUR 2 499 913"], "Project_Title": ["Dis-inhibitory circuits in the human cerebral cortex"], "Total_Cost": ["EUR 2 499 913"], "Country": ["United Kingdom", "United Kingdom", "Denmark"], "Project_ACR": ["INHIBITHUMAN"], "Technology_Description": "Temporal co-ordination of the activity of cortical neurons underlies cognitive processes. Intracortical inhibitory circuits set temporal windows for modulation of glutamatergic pyramidal cell firing. In non-human mammals, the activity of the GABAergic neurons is governed by other specialised GABAergic neurons, which can dis-inhibit pyramidal cells. The overarching aim of this project is to define cellular and pharmacological mechanisms of dis-inhibitory circuits in the human cerebral cortex. These circuits could act as regulators of cognitive process. First, we will investigate the neuron types and their synaptic influences to characterise how dis-inhibition controls synaptic integration and the output of neurons. Second, we will elucidate synaptic plasticity in dis-inhibitory circuits, as plastic events likely represent physiological substrates of cognitive operations. Third, we will identify the subcellular sites and the mechanisms of action of key receptors for ACh, monoamines, endocannabinoids, neuropeptides and mGluRs modulating dis-inhibitory circuits, which are targets of small molecule CNS drugs, such as cognitive enhancers. We will test three hypotheses: 1) the human cortical pyramidal cell output is gated by compartment-specific dis-inhibition mediated by specific interneurons; 2) activity-dependent plasticity occurs in dis-inhibitory circuits and has consequences for the output of cortical pyramidal neurons; 3) small molecule drugs act via dis-inhibitory mechanisms at cell-type specific sites altering the inhibitory dynamics of pyramidal cells leading to subcellular redistribution of inhibition and alteration in their output. Combined electrophysiology/imaging with neuropharmacology and high resolution molecular receptor localisation will generate an unprecedented knowledge of the human cortical circuits. Understanding human cortical neuronal connections and their responses to pharmacological interventions may also lead to novel therapeutic strategies.", "To": ["2021-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-12-01"], "Project_ID": ["694988"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 1 395 933"], "Project_Title": ["Algorithms for Complex Collective Decisions on Structured Domains"], "Total_Cost": ["EUR 1 395 933"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["ACCORD"], "Technology_Description": "Algorithms for Complex Collective Decisions on Structured Domains. ", "To": ["2020-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-07-01"], "Project_ID": ["639945"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 2 212 114"], "Project_Title": ["Immunological synapse derived ectosomes in T cell effector function"], "Total_Cost": ["EUR 2 212 114"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["SYNECT"], "Technology_Description": "The immunological synapse is a highly conserved scaffold for communication between immune cells built around cooperation of antigen and adhesion receptors. It often takes the form of a bull\u2019s eye with a central cluster of antigen receptors surrounded by a ring of adhesion molecules. We have recently observed that antigen receptor coated extracellular microvesicles bud directly from the center of the immunological synapse- which we define as synaptic ectosomes. Synaptic ectosomes are transferred to the antigen- presenting cell and can generate signals after the T cell-APC synapse has dissolved. We aim to determine the composition of synaptic ectosomes, determine their fate in the antigen-presenting cell and identify approaches to manipulate their formation in vivo. The objectives will be to 1) isolate synaptic ectosomes from human T cells and determine their molecular composition; 2) determine the functional impact of synaptic ectosomes on the antigen presenting cell; and 3) use gene targeting to control the process in vivo to understand its role in T function of helper, cytotoxic and regulatory T cells. The technologies will include microscopy, proteomics, genomics, and in vivo models with constitutive and conditional gene targeting. This work will address fundamental gaps in our understanding of immune cell communication.", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-11-01"], "Project_ID": ["670930"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 1 480 632"], "Project_Title": ["Coevolutionary Policy Search"], "Total_Cost": ["EUR 1 480 632"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["CoPS"], "Technology_Description": "I propose to develop a new class of decision-theoretic planning methods that overcome fundamental obstacles to the efficient optimization of autonomous agents. Creating agents that are effective in diverse settings is a key goal of artificial intelligence with enormous potential implications: robotic agents would be invaluable in homes, factories, and high-risk settings; software agents could revolutionize e-commerce, information retrieval, and traffic control.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["637713"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 1 954 633"], "Project_Title": ["Social Evolution and Social Engineering of bacterial Infections"], "Total_Cost": ["EUR 1 954 633"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["SESE"], "Technology_Description": "Micro-organisms were believed until recently to live independent, unicellular lives but are now understood to rely on complex systems of social behaviours for survival. In pathogenic bacteria, cooperation and communication between cells leads to increased virulence and the understanding of how these behaviours evolve is of fundamental importance to the future of human health. Almost nothing is known, however, about social behaviours of bacteria infecting human hosts, and research on social behaviour in microbes is limited to well-characterised lab strains. This proposal describes a program of research designed to exploit the opportunities offered by an interdisciplinary approach to address the growing challenge posed to human health by disease caused by bacterial infection. Specifically, I have three primary objectives: (1) to develop a model system for investigating social behaviour in long-term bacterial infections; (2) to identify evolutionary mechanisms driving dynamics of social behaviour in long-term infections and (3) to exploit social dynamics in the treatment of bacterial infection. This proposal applies evolutionary theory to the clinical challenge of bacterial infection to develop novel intervention strategies beyond the scope of conventional medicine, which is based primarily on understanding of bacteria at the cellular level.", "To": ["2020-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-08-01"], "Project_ID": ["647586"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 148 377"], "Project_Title": ["ExtraLytics: Big Data Analytics for Real Estate"], "Total_Cost": ["EUR 148 377"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["ExtraLytics"], "Technology_Description": "Data is becoming the key to effective decision making in more and more aspects of modern society. Big data analytics provide insight into complex processes considering a breadth of factors. This promises to increase the efficiency of decision making in areas such as policy making, research, product development, or financial and retail markets. Currently, big data analytics is employed only by technologically savvy organisations with control over the relevant data. This further exacerbates the information asymmetry that has been plaguing many of these areas: real estate where buyers have long suffered from limited information, often controlled by the seller; or retail markets where sellers are now employing sophisticated competitive price intelligence solutions unaffordable to buyers. Who can tell you if it is better to buy a house with a garden or with a garage; or where renovations will yield more rent over time? ExtraLytics answers these questions through a combination of big data extraction and analytics. ExtraLytics introduces analytics and prediction models into DIADEM\u2019s platform for accurate big data extraction from the web, which is able to extract required data at massive scale from the web. For the proof-of-concept, ExtraLytics initially focuses on residential real estate in the UK, a \u00a34,135bn market (UBS), where buyers and renters are required to make fast decision with limited information\u2014time on market is often below a week or even below a day as for desirable rentals in Oxford. \u201cIn an age when \u2018big data\u2019 is shaping our every move, how come an industry that takes so much profit can\u2019t keep pace with technology and use it to actually deliver a service worth the money they take in commission?\u201d (The Telegraph). ExtraLytics addresses this lack of data-driven analytics by giving consumers and investors alike a tool for better understanding properties, their location, their neighborhood, and their investment potential compared to other properties.", "To": ["2016-04-30, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2014 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2014-11-01"], "Project_ID": ["641222"], "Call_for_Proposal": ["ERC-2014-PoC"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Boundaries of Science: Medieval Condemnations of Philosophy as Heresy"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["BoundSci"], "Technology_Description": "\u2018Boundaries of Science: Medieval Condemnations of Philosophy as Heresy\u2019 addresses the limits we place on scientific investigation, according to our world view and what new ideas we are prepared to accept. It focuses on a critical example during the foundation of modern science in the 13th/14th centuries, when Aristotelian natural philosophy (books by Aristotle and his Muslim interpreters) entered Europe. This alien thinking caused a scientific revolution, but sparked controversy where theories denied Christian doctrines central to society\u2019s outlook. Church and university authorities opposing dangerous theories condemned them, and investigated scholars. This project builds on my surprising discovery that some medieval scholastics labelled theories heretical, but in fact the theories did not fit heresy\u2019s medieval definition. Curiously, some who used the term held risky positions. My objective is to determine whether scholastics considered dangerous theories heretical. Preliminary findings indicate some thought they should be classed as such; while others used the term for protection when holding risky views. Both groups acted strategically, to condemn or promote theories. I believe we witness here a negotiation process of where the boundary to permitted science should be drawn. My approach is new: historiography on the subject relies on scarce documentary evidence; instead I examine a rich source novel for this question, cases of scholastics calling theories heretical in philosophical/theological writings, and I analyse the context to determine their motivation. In redefining the philosophy/heresy relationship, I will give robust new perspective to the reception history and faith/reason problem. This innovative, multidisciplinary project will make a fact-based contribution to discussion of boundaries we place on scientific thinking, and will impact on how scholars and European society perceive the origins and development of our scientific heritage.", "To": ["2018-09-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-15"], "Project_ID": ["701523"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["TURUN YLIOPISTO", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "UNIVERSITY OF STRATHCLYDE", "ALBERT-LUDWIGS-UNIVERSITAET FREIBURG", "UNIVERSITA DEGLI STUDI DI MILANO", "UNIVERSITAT DE LES ILLES BALEARS", "University of Science and Technology of China"], "EU_Contribution": ["EUR 2 268 746"], "Project_Title": ["Quantum Probes for Complex Systems"], "Total_Cost": ["EUR 2 268 746,25"], "Country": ["Finland", "United Kingdom", "United Kingdom", "Germany", "Italy", "Spain", "China"], "Project_ACR": ["QuProCS"], "Technology_Description": "We are on the verge of a new scientific and technological era as the first quantum simulators able to investigate physical systems that cannot be studied classically are about to be built in the laboratories. Controlling and probing complex quantum systems is of paramount importance for the implementation of these devices.", "To": ["2018-03-31, ongoing project"], "Meta": [""], "Topic_s": ["FETPROACT-3-2014 - Quantum simulation"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-04-01"], "Project_ID": ["641277"], "Call_for_Proposal": ["H2020-FETPROACT-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 2 447 052"], "Project_Title": ["FLow of Ancient Metals across Eurasia (FLAME): New frameworks for interpreting human interaction in Later Prehistory"], "Total_Cost": ["EUR 2 447 052"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["FLAME"], "Technology_Description": "FLow of Ancient Metals across Eurasia (FLAME) is a new empirical and conceptual framework for understanding human interactions in Later Prehistory across all of Eurasia. Taking existing data on the chemical and isotopic composition of copper alloy objects and combining them with typological and chronological information within a GIS framework, FLAME aims to rewrite the history of human engagement with copper and its alloys across Eurasia, from Atlantic Iberia to the shores of the Pacific during approximately the 3rd to early 1st millennia BCE. It replaces the outdated concept of provenance with a completely new interpretative paradigm (\u2018form and flow\u2019), which is built upon the expectation that copper may be recycled, re-alloyed and generally re-used, thus breaking the simple linear assumption of a direct chemical or isotopic link between the copper and the ore from which it came. In this new paradigm, small shifts in chemistry are interpreted not necessarily as changing ore sources but also as the natural consequence of high-temperature processing and mixing, thus putting the emphasis on human interaction with metal rather than on sourcing. We will address major questions at a range of scales, from assemblage to continental, to look at how metal flowed literally and metaphorically through the complex societies of Bronze Age Eurasia. Our reassessment of the metallurgy will also be underpinned by new GIS frameworks and the creation of regional Bayesian-modelled radiocarbon chronologies. Previous scientific assessments of early metal have too often isolated the chemical and isotopic evidence from both the immediate archaeological context and any sense of a real time and place. FLAME brings together a broad range of skills to examine for the first time the intertwined social, scientific, chronological and geographical aspects of Eurasian early metallurgy.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["670010"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["The logics of information visualisation"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["LOGIVIS"], "Technology_Description": "Information visualisation is an essential tool in data-science, but the lack of a theoretical foundation currently prevents visualisation science to make substantial progress and develop solutions for the epistemological challenges posed by Big Data.", "To": ["2017-09-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["657017"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["A portable single-molecule fluorescence imager"], "Total_Cost": ["EUR 150 000"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["NANOIMAGER"], "Technology_Description": "This proposal focuses on activities that support the advancement of a novel compact optical microscope to the proof-of-concept stage. The microscope (\u201cNanoImager\u201d) is based on single-molecule fluorescence imaging; its development resulted from efforts to improve microscopes within the ERC project POLMACHINE. ", "To": ["2016-05-31, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2014 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2014-12-01"], "Project_ID": ["641252"], "Call_for_Proposal": ["ERC-2014-PoC"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Role, regulation and targeting of nucleic acid-sensing TLRs within the tumour microenvironment"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["Tolltum"], "Technology_Description": "Inflammation is an integral part of carcinogenesis. Several different cells of myeloid, lymphoid and non-hematopoietic origin contribute to the strong link between cancer and inflammation and maintain a pro-tumoral environment. The complexity of this environment and the diversity of tumours lead to distinct responses during tumour immunotherapies. Nucleic acid-sensing (NAS) TLR ligands are an essential component of anti-tumour strategies to induce efficient tumour-specific adaptive immune responses. NAS TLRs can also detect nucleic acid released during tumour necrosis, thereby modulating the tumour microenvironment. Interestingly, NAS TLR signalling can induce cell death via apoptosis or induce pro-tumoral survival and proliferation of cancer cells. These opposing effects of NAS TLR ligands may be due to the differential response of distinct tumour-associated cells to TLR ligands. Indeed, the individual response of subsets of tumour-associated cells remains unclear, thus making it difficult to predict the outcome of tumour immunotherapies. Furthermore, the expression and regulation of NAS TLRs in tumour-associated cells remains unknown. Using ex vivo cultures from adenocarcinomas and melanomas, we will systematically analyze the expression of all NAS TLRs on sorted cells. Using cutting edge technologies, we will dissect the role of TLRs in modulating the tumour microenvironment, which will provide novel insights into our ability to modulate cellular inflammation in the tumour. This proposal has the potential not only to reveal novel aspects of NAS TLR regulation, but also to provide new targets for the modulation of the tumour stroma and the infiltrating cells during carcinogenesis.", "To": ["2017-09-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["656757"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 1 497 271"], "Project_Title": ["Integrated and Detailed Image Understanding"], "Total_Cost": ["EUR 1 497 271"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["IDIU"], "Technology_Description": "The aim of this project is to create the technology needed to understand the content of images in a detailed, human-like manner, significantly superseding the current limitations of automatic image understanding, and enabling new far reaching human-centric applications. The first goal is to substantially broaden the spectrum of visual information that machines can extract from images. For example, where current technology may discover that there is a \"person\" in an image, we would like to produce a description such as \"person wearing a red uniform, tall, brown haired, with a bayonet, and a long black hat.\" The second goal is to do so efficiently, by developing integrated image representations that can share knowledge and computation in multiple computer vision tasks, from detecting edges to recognising and describing thousands of different object types.", "To": ["2020-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-08-01"], "Project_ID": ["638009"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 2 443 640"], "Project_Title": ["A Consolidated Library of Anglo-Saxon Poetry"], "Total_Cost": ["EUR 2 443 640"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["CLASP"], "Technology_Description": "As elsewhere in Europe, Anglo-Saxon England saw a development from an oral, vernacular, native, and pagan culture to one that was primarily literate, Latinate, imported, and Christian; and such a transition is clearest in Anglo-Saxon verse. CLASP will focus on all surviving verse of Anglo-Saxon England, composed in Old English and Anglo-Latin over a period of over four centuries (c. 670\u20131100 CE), and produce for the first time an online and interactive consolidated library, marked up through TEI P5 XML to facilitate the identification of idiosyncratic features of sound, metre, spellings, diction, syntax, formulas, themes, and genres across the entire corpus, so forging connections and suggesting more certain chains of influence both within and between the two main literary languages of Anglo-Saxon England. The bilingual corpus comprises almost 60,000 lines of poetry, with about half surviving in each language, and mostly appearing in only a single witness, usually in manuscript. More than fifty named poets are identified, many of them dateable with more or less precision, whose influence on each other can be closely documented, while in the case of anonymous verse, most of which is in Old English, the focus will be on tracing potential influence between texts, to establish a comparative rather than an absolute chronology. CLASP will use the full panoply of digital resources, including sound- and image-files where relevant, to make the oldest surviving poetry in England available to a modern audience for unprecedented kinds of exploration, comprehensive analysis, and interrogation, and in a series of conferences, workshops, and other publications will show the potential of such a comprehensive multilingual corpus to revolutionize perspectives not only on Anglo-Saxon England, but elsewhere in Europe, where Latin and the vernacular likewise co-existed in a Christian context across centuries.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["695262"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 145 501"], "Project_Title": ["Integral Membrane Proteins \u2013 an Approach to Rank Target Stability"], "Total_Cost": ["EUR 145 501,25"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["IMPARTS"], "Technology_Description": "This Proof of Concept proposal is designed to develop and test a novel way of monitoring the effects of drug binding to membrane protein targets. The idea stems from the basic research proposed in my ERC grant IMPRESS to study and rationalise the release of membrane proteins from detergent micelles in the gas phase of the mass spectrometer. During this research we discovered a new family of detergents, which we could formulate, to retain folded protein structure in the gas phase. Having achieved this goal, we then actively unfolded these assemblies in the mass spectrometer and by monitoring their unfolding trajectories we realised that we could quantify the effects of small molecule binding on protein stability. Not only can we now rank ligands according to their ability to confer stability but we can also count the number of molecules bound to a particular membrane protein target. By distinguishing bound molecules, either lipids or drugs, we can then carry out competitive binding experiments by displacing small molecules with higher affinity ligands.", "To": ["2016-08-31, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2014 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-03-01"], "Project_ID": ["641317"], "Call_for_Proposal": ["ERC-2014-PoC"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Network Techniques for Interaction Quenches"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["NET4IQ"], "Technology_Description": "Understanding the universal features of the non-equilibrium dynamics of strongly interacting one-dimensional quantum many-body systems is one of the most challenging and intriguing aspect of the recent researches in the broad domain of the quantum many-particle physics. In this project one merges analytical with numerical methods in order to explore the exotic behavior of interacting quantum models when brought out-of-equilibrium. Indeed, although the equilibrium properties of quantum systems could be understood in terms of standard approaches, away from the equilibrium a complete understanding is still missing. In particular, the project aims to fill the lack of knowledge still present in this exciting domain, pursuing two main ideas: (i) The development of new numerical methods based on tensor-network techniques, so as to explore the post-quench dynamics in closed quantum systems; with a special attention to the very recent continuous version of such algorithms. (ii) A better theoretical understanding (strongly supported by the numerical approach in (i)) of the effects of symmetry breaking, interactions and integrability, in the non-equilibrium dynamics; especially with respect to the non-equilibrium transport of energy and particle throughout the systems as well as a universal description of the stationary states (both equilibrium and non-equilibrium) that emerge at late times. ", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["701221"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE UNIVERSITY OF HERTFORDSHIRE HIGHER EDUCATION CORPORATION"], "EU_Contribution": ["EUR 2 499 980"], "Project_Title": ["Divergent modes of ritual, social cohesion, prosociality, and conflict."], "Total_Cost": ["EUR 2 499 980"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom"], "Project_ACR": ["RitualModes"], "Technology_Description": "The project aims to establish an authoritative scientific framework for understanding the relationship between group ritual, social cohesion, and pro-group behaviour. Rituals have shaped human societies for millennia, but the exact social consequences of rituals are poorly understood. The proposed research will identify the fundamental components of rituals worldwide and chart their effects on patterns of group alignment and action. Doing so will have a lasting impact on basic understandings of the nature, causes, and consequences of ritual dynamics as well as open up exciting new avenues of inquiry that bridge the humanities and social sciences. ", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["694986"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Imaging nucleic acid metabolism in cells"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["INAME"], "Technology_Description": "In this project I, Pawan Kumar, a Nucleic Acid Chemist seek to team up with a pioneer in Nucleic Acid Chemistry and Biology (Professor Tom Brown) to carry out a highly interdisciplinary study at the University of Oxford to obtain deeper insights into DNA and RNA synthesis and metabolism in living cells and its application to cancer research. I propose to detect and quantify nucleic acid synthesis in proliferating cells by fluorescence without the requirement for toxic metal ions or antibodies. Earlier known methods such as [3H]thymidine and 5-bromo-2'-deoxyuridine labelling are either slow and labour intensive or require the use of harsh conditions. Incorporation of 5-ethynyl-2'-deoxyuridine into newly synthesized DNA and its subsequent detection with an azide derivative of a fluorescent dye under copper catalyzed alkyne azide cycloaddition (CuAAC) reaction conditions presents a better alternative. However, cytotoxicity of copper salts restricts its use for living cells. I will use the strain promoted alkyne azide cycloaddition reaction, Diels-Alder reaction, and inverse electron demand Diels-Alder reaction to study cellular DNA and RNA. None of these reactions require the use of toxic metal salts. I will develop the conditions under which both DNA and RNA will be stable, so that it will be possible to isolate intact fluorescent nucleic acids from cells for detailed analysis. I will prepare the modified nucleosides and use them to label newly synthesized DNA and RNA in cells enabling their detection by reaction with fluorophores by using metal free click ligation reactions. The study will provide a better understanding of the mechanisms regulating DNA replication and the interplay between transcription and DNA replication. In the project I will develop techniques to provide information on the toxic effect of antimetabolites used commonly in anti-cancer therapies, and for identifying the mechanisms of viral replication and understanding the viral life cycle.", "To": ["2018-01-03, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-01-04"], "Project_ID": ["656872"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Chemical Tools to Probe the Role of Bromodomains in the Parasite Trypanosoma cruzi"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["jamclay"], "Technology_Description": "Lysine acetylation is a key protein post-translational modification (PTM) found throughout the cellular environment and across the range of species. This PTM is dynamic, with histone acetyl transferases (HATs) acetylating lysine, and histone deacetlyases (HDACs) reversing the modification. In addition, proteins modules bromodomains, have been identified that bind to acetylated lysine (KAc) and mediate protein-protein interactions. In humans, bromodomains exist as part of larger proteins, many of which are involved in transcriptional regulation. Bromodomains contain a KAc-binding pocket for which small molecule ligands have been identified. These ligands prevent the interaction of bromodomains with KAc and have been invaluable in dissecting the fundamental biology mediated by bromodomain-containing proteins (BCPs). We and others have developed potent ligands for the human bromodomain and extra C-terminal domain (BET) bromodomains. These compounds have antiproliferative effects in cancer cells lines and modulate inflammation and atherosclerosis. This work led to an explosion of interest in developing BET bromodomain inhibitors, resulting in 5 compounds in clinical trials. Despite rapid progress in understanding the role of human bromodomains, their function in other species is poorly understood. Given the fundamental role played by bromodomains in humans, we hypothesise that BCPs will play equally important roles in other organisms.", "To": ["2018-03-23, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-03-24"], "Project_ID": ["658825"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Bacterial motion in polymer solutions and biogels"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["GelSwimming"], "Technology_Description": "Many cavities in the human body such as the lungs, the stomach or the reproductive tract are covered and protected by a thin layer of mucus gel. Under certain conditions pathogenic bacteria are able to penetrate the mucus layer which leads to serious infections. For example, in cystic fibrosis motile bacteria swim through the mucus layer and form biofilms which can be resistant to antibiotic medication. Interestingly, corals in the ocean are also covered by mucus. Again, pathogenic bacteria are able to penetrate the coral mucus layer and cause serious diseases resulting in a world-wide decline of corals. The underlying mechanisms how the bacteria are able to move through mucus are not yet understood. We aim, in our proposal, to clarify physical conditions under which bacterial locomotion in polymer solutions and gels is possible. In contrast to existing theories on swimming in viscoelastic fluids we explicitly model the gel and the bacteria via mesoscale computer simulations. Our novel approach will enable us to identify the microscopic conditions for bacterial locomotion in gels and the conditions for immobility (gel-trapping). Our findings may also inspire biologists and medical researchers in designing novel medication and finding strategies to avoid bacterial invasion into mucus of relevance to both the prevention of human disease and the degradation of corals.", "To": ["2018-02-25, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-02-26"], "Project_ID": ["653284"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Combined Catalysis: Enhancing Asymmetric Synthesis"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["CombiCat"], "Technology_Description": "The stereoselective synthesis of small organic molecules depends on robust catalytic methods. Despite many advances in enantioselective synthesis, an unsolved challenge in catalysis is the translation of enantioselective catalytic reactions to diastereoselective reactions \u2013 where a chiral catalyst controls the outcome of reaction of a chiral substrate. ", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["702385"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "HELSINGIN YLIOPISTO"], "EU_Contribution": ["EUR 1 998 375"], "Project_Title": ["Bio-Imaging of Zoonotic and Emerging Bunyaviruses"], "Total_Cost": ["EUR 1 998 375"], "Country": ["United Kingdom", "United Kingdom", "Finland"], "Project_ACR": ["BIZEB"], "Technology_Description": "We aim to understand host cell entry of enveloped viruses at molecular level. A crucial step in this process is when the viral membrane fuses with the cell membrane. Similarly to cell\u2013cell fusion, this step is mediated by fusion proteins (classes I\u2013III). Several medically important viruses, notably dengue and many bunyaviruses, harbour a class II fusion protein. Class II fusion protein structures have been solved in pre- and post-fusion conformation and in some cases different factors promoting fusion have been determined. However, questions about the most important steps of this key process remain unanswered. I will focus on the entry mechanism of bunyaviruses by using cutting-edge, high spatial and temporal resolution bio-imaging techniques. These viruses have been chosen as a model system to maximise the significance of the project: they form an emerging viral threat to humans and animals, no approved vaccines or antivirals exist for human use and they are less studied than other class II fusion protein systems. Cryo-electron microscopy and tomography will be used to solve high-resolution structures (up to ~3 \u00c5) of viruses, in addition to virus\u2013receptor and virus\u2013membrane complexes. Advanced fluorescence microscopy techniques will be used to probe the dynamics of virus entry and fusion in vivo and in vitro. Deciphering key steps in virus entry is expected to contribute to rational vaccine and drug design. During this project I aim to establish a world-class laboratory in structural and cellular biology of emerging viruses. The project greatly benefits from our unique biosafety level 3 laboratory offering advanced bio-imaging techniques. Furthermore it will also pave way for similar projects on other infectious viruses. Finally the novel computational image processing methods developed in this project will be broadly applicable for the analysis of flexible biological structures, which often pose the most challenging yet interesting questions in structural biology.", "To": ["2020-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-04-01"], "Project_ID": ["649053"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["An evolutionary approach to automated norm synthesis for multi agent systems"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["EVNSMAS"], "Technology_Description": "The field of multi-agent systems (MAS) is concerned with the theory, design, and implementation of systems of semi-autonomous software agents that operate in an environment, and typically have conflicting goals. A key issue in such domains is that of coordination: how to design agents to minimise any potential negative aspects of their interactions, and to maximise any potential positive aspects. A key approach to coordination is that of normative systems. A normative system defines constraints on the behaviour of agents to coordinate their interactions. This research programme is at the intersection of normative systems design and evolutionary game theory (EGT). EGT studies how evolutionary forces can lead populations to game theoretic solutions, and has been useful in understanding, for example the distributions of populations of species in habitats. The hypotheses of this project are that (1) EGT can provide a useful mathematical framework to model and understand normative systems in MAS; and (2) EGT techniques can provide a powerful framework to engineer normative systems for MAS. Thus, norm synthesis will consist of an evolutionary process in which most successful norms will prosper, while unsuccessful norms will be naturally discarded. The tools used to understand such norms will be solution concepts from EGT - notably the concept of an evolutionarily stable strategy. In this project we will develop both frameworks for understanding EGT for normative systems design and to synthesise normative systems for MAS, and we will empirically investigate our techniques in the context of two application domains. To carry out this project the fellow will be trained in classical game theory and EGT. To this aim he will benefit from supervision of Prof Michael Wooldridge, and collaboration with his research group in Oxford. This project will develop science and will contribute to the development of the fellow's career plan to become an independent researcher.", "To": ["2018-06-05, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-06-06"], "Project_ID": ["707688"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["VINYL AND HETEROARYL BORONIC ACIDS AS NON-STABILIZED NUCLEOPHILES IN RHODIUM-CATALYZED DYNAMIC KINETIC TRANSFORMATIONS"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["BORONDYKAT"], "Technology_Description": "The formation of carbon-carbon bonds in an asymmetric fashion is a very useful process in synthetic chemistry, since it generates single enantiomers of chiral molecules at the same time as the molecular framework is being assembled. In this context, two strategies for the generation of single enantiomer compounds using enantioselective catalysis have been widely emabraced: on the one hand, the use of prochiral substrates, and on the other hand, the use of racemic substrates in enantiomer resolution processes, which limits the yields up to 50%. An efficient variation of this second strategy is to couple enantiomer differentiation with interconversion of enantiomers. However, these dynamic kinetic asymmetric transformations (DYKAT) have been limited to the use of stabilized nucleophiles. Very recently, the group of Fletcher reported that alkylzirconium reagents can be employed as non-stabilized nucleophiles in combination with a copper-based catalytic system for this class of processes. Subsequently, the same group demonstrated that arylboronic acids are also suitable substrates in rhodium-catalyzed DYKATs. The project presented in this application aims to expand the scope of this powerful transformation by using vinyl- and heteroarylboronic acids as non-stabilized nucleophiles in the rhodium-catalyzed DYKAT. Moreover, a thorough study of the reaction mechanism will be conducted, as well as the investigation on alternative procedures for this process (catalytic systems, nature of the substrates, etc) that might result in useful applications for organic synthesis.", "To": ["2018-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-08-01"], "Project_ID": ["700108"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Quantum Broadband Optical Solid-State Memories for Large-Scale Photonic Networks"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["Quantum BOSS"], "Technology_Description": "Large-scale quantum photonic networks promise to revolutionize computational processing and communication with the use of fundamental quantum-mechanical concepts. Limited by scalability, the field of quantum information processing (QIP) is so far lacking a real world, large-scale implementation that can allow for quantum computation and long distance quantum communication. These applications in QIP have distinct advantages over their classical counterparts. Quantum computation promises to provide unprecedented speed-up in processing for problems that are intractable for classical computers, while remote entanglement generation and swapping would allow long distance quantum networking. Integral to a functioning quantum network is a quantum optical memory (QM), a device allowing for the faithful storage and recall of quantum states of light using a strong and controllable light-matter interaction. The main scientific vision of this project is to develop multiple cavity-enhanced, broadband and long-lived QMs capable of long distance distribution of entanglement and multi-photon state generation. The resulting technology will provide the necessary resources for long-distance quantum communication and scalable quantum computing. The former is obtained by the heralded entanglement of two remote QMs to form an \u2018elementary link\u2019, and then swapping the entanglement between multiple links. The objective of this project is to implement the QM in a solid-state, scalable architecture.", "To": ["2018-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-11-01"], "Project_ID": ["705278"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Approaching efficiency limits of perovskite solar cells by overcoming non-radiative recombination losses"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["APPEL"], "Technology_Description": "Metal halide perovskites are currently viewed as a new \u201cwonder materials\u201d due to the combination of their outstanding optical and electronic properties with the ease of processing as compared to similar direct bandgap semiconductor such as GaAs. Despite the meteoric rise of the power conversion efficiency of perovskite solar cells (up to 20% in less than 5 years) they is still a substantial potential of improvement towards the theoretical efficiency limits. During the first research phase, most of the effort has been devoted to the development of deposition processes to produce the best crystalline thin films. APPEL has the ambition to initiate the second phase, in which fundamental understanding of the recombination losses in the perovskite and at heterojunctions with charge extraction layers will make possible to generate devices with efficiencies approaching the full potential of these semiconductors. A perfect solar cell should also be an excellent emitter, since 100% of the absorbed photons must recombine radiatively. Therefore the original approach APPEL is to target primarily light emission (photoluminescence and electroluminescence) to understand the factors governing the recombination losses in solar cells. From the understanding of the fundamental recombination mechanisms at the heterojunctions, I will demonstrate highly efficient devices with >23% power conversion efficiency. Moreover, efficient light-emitting diodes (LED) will be produce alongside photovoltaic devices. This work will set the foundation of the future rational optimisation of metal halide perovskite devices in the same way that optimisation of light emission in GaAs led to the advent of devices approaching the theoretical limits.", "To": ["2018-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-11-01"], "Project_ID": ["706552"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Selectively Targeting Oscillations in Parkinson's disease: Causal effects of the beta-rhythm on motor control"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["STOP-Beta"], "Technology_Description": "Parkinson\u2019s disease is a frequent and disabling neurological disorder, which heavily impairs patients\u2019 ability to perform and control movements. Electrical stimulation of a deep-seated brain region, the subthalamic nucleus (STN), has been shown to significantly improve patients\u2019 motor function and quality of life. Recent technological advances in deep brain stimulation (DBS) render it possible to adjust electrical stimulation of the STN to ongoing brain activity, referred to as closed-loop DBS. Here, the implanted electrodes do not only send signals to the brain but also read out neural signals generated by the brain. Closed-loop DBS offers the intriguing possibility to specifically suppress pathological brain activity while leaving physiological activity unaltered. ", "To": ["2017-04-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-05-01"], "Project_ID": ["655605"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Molecular Spintronics using Isolated Rare Earth Magnets"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SpinReMag"], "Technology_Description": "A revolution is underway, as the fast-paced electronics industry moves towards the nanoscale, researchers are starting to consider single-molecule electronics. Such devices are within reach partly due to a new field, called molecular spintronics, which permits the prospect of controlling both spin and charge in single molecules. On the other hand, we know almost nothing about how a magnetic molecule is affected by electrons flowing through it or what chemical ingredients it takes to construct perspective devices. SpinReMag will investigate these uncharted waters by exploring the boundary between chemistry and single-molecule read-out technology. SpinReMag is a strongly multidisciplinary project utilizing an innovative mix of synthetic chemistry, physics and materials methodology to overcome present experimental limitations. Our design approach is to investigate single-molecule junctions, except instead of placing a molecules between bulk electrodes, we will directly grow photoactive groups on the molecule so that electrons will flow through or close to the spin center after a light pulse. This affords an ultra-clean system that can be studied in bulk, with a perfectly defined geometry of the magnetic and electronic elements. SpinReMag will provide the fundamental ground work to explain how molecular spins interact with flowing electrons. The execution of this project will for the first time provide the understanding of fundamental spintronic processes, and open new pathways to the rational design of single-molecule spintronics. The information gathered by SpinReMag will direct the future of research in single-molecule electronics and in the optical control of spin systems in general.", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-03-01"], "Project_ID": ["707252"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Molecular mechanisms of rhomboid-like proteins in human immunity"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["RhomBioID"], "Technology_Description": "The immune system coordinates vital responses against a plethora of threats. It relies on well-described signalling networks via soluble proteins and cell-to-cell contacts. The secretory pathway traffics all secreted and surface proteins, but the mechanism of how immune cells control this process is unclear.", "To": ["2017-04-06, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-04-07"], "Project_ID": ["655035"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["How prior brain states govern access to working memory"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ACCESS2WM"], "Technology_Description": "The ability to temporarily maintain and manipulate information in working memory (WM) is critical for adaptive behaviour. Because WM has limited capacity, it is essential to understand the mechanisms that govern selective access to it. I hypothesise that 1) selective access to WM is governed by states of the brain prior to the encoding and retrieval of sensory information (in particular the phase and amplitude of neural oscillations in the different sensory cortices), and that 2) changes in these states provide a common neural substrate through which several cognitive variables affect WM. I will use magneto-encephalography (MEG) to investigate several key aspects of these central hypotheses in healthy human volunteers. This will advance our understanding of the neural and cognitive mechanisms that govern selective access to WM and could ultimately be used to present relevant information when the brain is most susceptible to incorporate this into WM. The project will be carried out at the Oxford Centre for Human Brain Activity, together with leading scientist in the electrophysiological study of WM (Anna Christina Nobre and Mark Stokes) and the analysis of MEG data (Mark Woolrich). This will allow me to not only perform the proposed research to the highest standard, but also to further develop several key skills (broaden my conceptual horizon, acquire novel analysis techniques, establish long-term collaborations, translate research, etc.) that will further my independence as a researcher and place me in the ideal position to start my own research group within few years after the fellowship.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["655374"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["An innovative approach for the study of culinary practices in past societies"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["CUISINE"], "Technology_Description": "The aim of this project is to develop an innovative methodology for the study of culinary practices (cuisine) in past societies integrating the morpho-typological analysis of cooking pots, the analysis of their lipid content and the analysis of microbotanical remains. By analysing a society's diet and cuisine we can explore, for instance, cultural development expressed through growing complexity in parallel with the development of more complex social and technological structures. This project will explore culinary practices in past societies through the integrated analysis of phytoliths, starch grains and lipids from cooking pottery. In order to interpret the archaeological record, extensive plant reference collections and several experiments will be developed as part of the project. At the same time, the methods developed during the experimentation phase will be tested and validated on two archaeological case studies in the Aegean, an area that has historically been (and still is) a crossroad for people and foodstuffs: the Neolithic site of Stavroupoli (Greek Macedonia, ca. 5600-5000 cal. BC) and the Bronze Age site of Knossos-Gypsades (Minoan Crete, ca. 3650-1100 cal. BC). The development of these integrated analyses on Neolithic and Bronze Age settlements will allow for the study of the emergence of new social practices and cultural identities linked to the origins of food production and the development of complex, urban societies.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["704867"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Development of fluorescence nanospectroscopy to elucidate the roles of nanoscale molecular segregation in the activation of T-cells"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["FNS-4-NAMOSAT"], "Technology_Description": "BACKGROUND", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["707348"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Total Synthesis of Biologically Important Pyrrolidinone Natural Products and Analogues Thereof."], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SYNOX"], "Technology_Description": "\"The importance of natural products and derivatives as sources of new drugs is undeniable. Newman has stated:", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["708354"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Selecting, Creating and Modifying Embryos: the ethics of new reproductive genetic technologies"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SCME"], "Technology_Description": "For over three decades reproductive technologies have been available which allow parents to select between embryos based on their genetic makeup. Soon two novel ways of influencing a child\u2019s genome could also become available. In 2013, personal genomics company 23andMe received a patent to a technology called \u2018Gamete Donor Selection Based on Genetic Calculations.\u2019 This technology would allow individuals accessing assisted reproductive services to choose between sperm or egg donors based on the likelihood of the embryos having a particular genetic makeup. Technologies like this allow parents to create rather than select embryos with desirable genetic characteristics. In addition genetic engineering technologies continue to improve. The recently developed \u2018CRISPR\u2019 technique provides a more precise way of altering the genome than previous methods, and is the first modification technology with real potential to be used on human embryos. Technologies like this may allow parents to modify the genetic material of existing embryos. ", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["659700"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Experiences and Memories of French and Algerian Veterans. Remembering the 'petite guerre' in the Aur\u00e8s-Nememcha"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["PETITE GUERRE"], "Technology_Description": "The present study aims to investigate the Algerian War of Independence (1954\u201362) from a new perspective. It proposes to frame a transnational history of the war, going beyond both the (opposing) French and Algerian (national) narratives, to resituate the war in its Mediterranean, European, and eventually its global contexts. This general research objective, however, will be achieved by using a microhistorical approach: instead of looking at the conflict as a generic \u201cwhole\u201d and examining its reverberations in an elusive \u201ccollective memory\u201d, the project focuses on a specific region, the Aur\u00e8s-Nememcha in the Algerian south-east. At the core of this project are the specific experiences and memories of French and Algerian veterans who fought each other for eight years, in this mountainous, Berberophone area. Who were they? What kind of war were they fighting, and why? And fifty years after the ceasefire, how do the citizens of each country cope with their combat memories? The project will mobilise a wide range of sources, mostly but not exclusively French and Algerian. Aiming to analyse both past events and their present memories, this study will rely on both qualitative and quantitative analytical methods, in a truly interdisciplinary framework. Indeed, this \u201cglobal microhistory\u201d approach\u2014beyond being an original contribution to historical research\u2014aims to offer new knowledge of and insights into the Franco-Algerian War, in order to help the two countries to go beyond the narrow national narratives that continue to fuel an unexhausted \u201cmemory war\u201d that is ongoing both between and within Algeria and France. If the efforts of the EU and the Union for the Mediterranean (2008) may help to set a new tone in the near future, today it is less at the state level that it is possible to act than at the level of the people, by focusing on their particular and familial stories.", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["656782"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Site-selective chemical pyrophosphorylation of proteins using tag-and-modify approach."], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["PyroPhosphoProtein"], "Technology_Description": "Post-translational modifications (PTMs) occur on nearly all proteins in eukaryotic cells to diversify their proteome. These chemical modifications of various amino acids side chains can influence protein association with other biomolecules, or control cellular signal transduction networks and the activity of enzymes. Reversible protein phosphorylation is one of the most common PTMs. It is considered as a signalling mechanism involved in almost all cellular processes. On the other hand, protein pyrophosphorylation mediated by the inositol pyrophosphate messengers was discovered recently and its function on proteins is completely unknown. Up to date, direct evidence of its role in vivo is still missing. Exploring the potential role of protein pyrophosphorylation is limited by lack of a robust method of installing pyrophosphate residue in desired position of full length proteins. Here we propose chemical site-specific pyrophosphorylation of proteins using \u201ctag-and-modify\u201d approach. It relies on expression of protein bearing cysteine in the position of interest. The cysteine is then chemically converted to dehydroalanine (\u201ctag\u201d), which reacts with various sulphur or carbon nucleophiles under mild conditions to introduce pyrophosphate PTM mimics (\u201cmodify\u201d). The method allows preparation of not only pyrophosphorylated proteins, but also their phosphatase resistant analogues. These will be invaluable for mechanistic studies of pyrophosphorylation reversibility and its biological role. As a proof of concept, well defined chemically pyrophosphorylated transcriptional factor GCR1 will be prepared by proposed strategy. The influence of GCR1 pyrophosphorylation on interaction with GCR2 will be explored, since this is assumed to control transcription of glycolytic genes in yeast. Our new technique for the site-specific chemical synthesis of pyrophosphoproteins will provide long awaited tool to gain a better understanding of the physiological role of this novel PTM.", "To": ["2018-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-04-01"], "Project_ID": ["700124"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Sustainable Mixed-ion Layered Perovskite Solar Cells"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["MPerS"], "Technology_Description": "We propose to create and investigate new types of organic-inorganic perovskite materials for low-cost solar cells. The state-of-the-art perovskite based solar cells employ MAPbI3, which has raised concerns over the potential toxicity of Pb. The strategy of the MPerS project is to create, investigate and optimise sustainable perovskite materials for solar cell application. More than one types of metal and organic ions will be introduced in the perovskite structure to realize layered materials which are expected to exhibit both excitonic and free carrier behavior with enhanced stability. Thin films of the new materials will be characterized using several techniques, e.g. Xray diffraction. THz, Time resolved emission spectroscopies, EBIC will be used to understand the generation and dynamics of charge carriers in the materials and across interfaces. Development of solar cells will be carried out with an aim to reach 15% power conversion efficiency employing a non-toxic absorber. This highly interdisciplinary project that spans the field of chemistry, condensed matter physics, electronics and engineering is conceived on basis of the combined expertise of the host and the applicant and state-of-the-art infrastructure at the UOXF. A secondment at Oxford PV will test the commercial viability of the project. This project addresses Horizon 2020\u2019s goals on clean and sustainable energy and the EU\u2019s concern on toxicology of Pb . Completion of the project will open up new areas in low-cost electronic materials with wider impact and improve EU\u2019s competitiveness in materials research. While the applicant will get an opportunity to learn new experimental skills in condensed matter physics and spectroscopy and benefit from industrial exposure. UOXF will benefit from the applicant by using his skills and broader broader collaboration with leading researchers in materials science. A plan is also proposed to carry out public engagement, dissemination and commercial exploitation.", "To": ["2017-03-31, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-04-01"], "Project_ID": ["653184"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Multi-resolution Fracture Models for High-strength Steels: Fully Ductile Fracture to Quasi-cleavage Failure in Hydrogen Environment"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["FraMoS"], "Technology_Description": "Recent advances in Computational Mechanics are towards the development of predictive tools that can accelerate the 'Materials Development Cycle' by unraveling the linkage between macroscopic properties and microstructure. The availability of 3D tomographic tools and the era of Exascale computing have initiated the quest to develop stronger, tougher and more durable alloys by employing 'virtual predictions' in lieu of expensive destructive testing. However, our lack of understanding of the 'structure-toughness\u2019 relations is one of the main bottlenecks in this pursuit. Moreover, the uptake of some of these new alloys (TRIP, TWIP etc) is hampered by the concerns of hydrogen (H) induced cracking. ", "To": ["2018-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-12-01"], "Project_ID": ["701897"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 251 857,80"], "Project_Title": ["Organic-Inorganic perovskite and organic semiconductor films with improved crystal properties via reel-to-reel solution coating; application to photovoltaics and field effect transistors"], "Total_Cost": ["EUR 251 857,80"], "Country": ["United Kingdom"], "Project_ACR": ["Crystal Solar"], "Technology_Description": "This project will develop low cost and scalable solution\u2013based coating techniques to yield electrically tunable films with macroscopic crystalline domains of both organic\u2013inorganic perovskite and organic semiconductors. These layers will be used to prepare solution processed hybrid perovskite-based photovoltaic (PV) devices surpassing 20 % solar-to-electricity power conversion efficiency, to provide a low cost and renewable energy supply. The researcher will carry out the processing and characterization of the materials at Professor Zhenan Bao's laboratory at Stanford University. Professor Bao is a world leader in using solution deposition techniques to tune the physical and electronic properties of solution-processed semiconductors for use in FETs, and is well suited to extend this approach to perovskite PV. The skills and knowledge obtained at Stanford University will be brought back to Professor Henry Snaith's laboratory at Oxford University and to Oxford Photovoltaics ltd to prepare low cost, scalable perovskite PV with enhanced macroscopic crystal properties and performance. Professor Snaith is recognized as one of the pioneers in perovskite based PV, and is thus excellently placed to guide the researcher in the development of PV with superior performance for eventual employment as large-scale energy supply. This project will form a unique union of two world leading research groups with complementary expertise. There is great potential for the transfer of skills, generation of intellectual property, and industrial involvement within the EU via the ISIS program at Oxford University, and the company Oxford Photovoltaics of which Professor Snaith is the CTO.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["659225"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["MARTIN-LUTHER-UNIVERSITAET HALLE-WITTENBERG"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Using Land Cover Change Models to Address Important Conservation Issues"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["LCCMcons"], "Technology_Description": "Anthropogenic land use/land cover change (LULCC) is now one of the major causes of biodiversity loss and the second largest source of carbon emissions to the atmosphere. Policy-makers face a challenging task when making decisions that impact the future of the landscapes with great levels of uncertainty about its outcome. Spatially-explicit LULCC models can be important tools to help assessing the outcome of such decisions a piori. However, modelling anthropogenic processes is a great challenge. Not only is the physical environment itself highly variable, but the underlying processes that drive LULCC combine socio-economic, cultural, political and environmental factors. Although enormous advances have been made in the field of LULCC modelling over the past couple of decades, there is room for improvement as these models still lack the ability to project both the rate and location of future change accurately. Improving these models would dramatically increase their potential to help solving real-world problems. Therefore, this research proposal will improve an existing LCCM to be able to incorporate region- and land-use transition specific parameters, representing observed relationships between proximate causes and drivers of LULCC, which vary over time and space. By the means of two real-world case studies, on different biomes (Serengeti-Mara Ecosystem and the Brazilian Atlantic Forest), this project will show how a LULCC model can be used to tackle two important worldwide conservation issues: the conflict between infrastructure development and conservation (Serengeti) and the impacts of implementing financial incentives to promote forest restoration (Atlantic Forest). Ultimately, this research proposal will provide a framework for robust decision-making under uncertainty, particularly when considering potential trade-offs between socio-economic and ecological implications at different scales, and a tool for aiding management of stakeholders' conflicts due to LULCC.", "To": ["2018-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["703862"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Development and in situ Infrared study of Novel Strained Core-shell Electrocatalysts: Towards an Understanding of the Oxygen Reduction Mechanism"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ORRmetIR"], "Technology_Description": "The oxygen reduction reaction (ORR) is critical in fuel cells (FC), batteries and corrosion. Sluggish kinetics of the ORR remains a key barrier to efficient electricity generation in FC operating on renewable fuels such as hydrogen or alcohols. Poor understanding of the ORR mechanism has hindered development of cost-effective and improved FC catalysts. ", "To": ["2017-03-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-04-01"], "Project_ID": ["659306"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["The Role of Adipose-Tissue Derived wnt-ligands in the Regulation of Myocardial Redox Signalling"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["REDOxHEART"], "Technology_Description": "Myocardial redox signalling is a critical regulator of myocardial physiology and a therapeutic target in cardiovascular science, while obesity seems to trigger myocardial oxidative stress. The non-canonical wnt signalling pathways (Ca2+-dependent (CDP) and planar cell polarity pathway (PCP)) are important in cardiac development and they are also involved in obesity (wnt ligands are involved in adipose tissue expansion), although their role in the adult myocardium is unknown. We propose to define the role of CDP and PCP in the regulation of myocardial redox state in the human adult heart. We will perform a) Clinical association studies using tissue from patients undergoing cardiac surgery to test for paracrine effects of adipose tissue on myocardial PCP/CDP regulation b) Studies using ex vivo models of human myocardium (trabeculae) to test the role of CDP/PCP in myocardial redox state regulation c) Cell culture studies using primary human cardiomyocytes to explore the mechanisms of these effects d) Animal studies using a novel transgenic mouse model to test causality of the associations. In this translational study we will explore for the first time the role of CDP/PCP in the regulation of myocardial redox signalling and evaluate its role in cardiac physiology. This work may identify novel disease biomarkers and therapeutic targets for the treatment of myocardial diseases.", "To": ["2017-06-30, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-07-01"], "Project_ID": ["656990"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 149 983"], "Project_Title": ["Perovskite Light Emitters"], "Total_Cost": ["EUR 149 983"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["PLE"], "Technology_Description": "Metal halide perovskites have recently astonished the research community and garnered a mass following to realize extremely high efficiency low cost photovoltaics. This work was largely catalyzed by outputs from the ERC-Stg HYPER, but in addition to solar cell applications, these materials could also be near perfect light emission materials for displays and lighting. This POC grant will formulate a strategy to move the perovskite materials and device research towards commercial exploitation as light sources. Within the project an assessment of the impact perovskite nanocrystals could have in the current lighting market will be undertaken, and a strategy to capitalise upon exiting Oxford IP and how best to develop foreground IP will be formulated. To complement these activities, a demonstrator perovskite light source will be created. From the derived information on IP and business development, a business plan will be delivered which will be taken to the investor community following successful completion of the POC project. This project will therefore enable the transition for perovskite light emitting nanocrystals from University research to a commercial venture.", "To": ["2017-06-30, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2015 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["693144"], "Call_for_Proposal": ["ERC-2015-PoC"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Multiscale dynamics of astrophysical plasmas: pressure-anisotropy-driven instabilities and large-scale dynamical processes"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ASTROMULTISCALE"], "Technology_Description": "The primary purpose of the proposed project is a deeper understanding of instabilities in plasmas and their influence on transport phenomena and large-scale dynamical processes. The studies will be focused on nonlinear regime of development of the firehose and mirror instabilities triggered by pressure anisotropy spontaneously generated in stellar-wind environments by large-scale expansion/compression effects and plasma turbulence. Recent studies of microphysics of the instabilities have provided systematic knowledge on saturation effects in nonlinear regime and related wave-particle interactions. This opens a possibility of investigation of a feedback between the microphysics and large-scale dynamics. The project is anticipated to provide answers to the questions: what is the effective collisionality of a pressure-anisotropic plasma that is unstable or marginally stable to the firehose and mirror instabilities and how does it change the effective pressure tensor (viscous stress) used in fluid description of plasmas?", "To": ["2017-05-31, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-06-01"], "Project_ID": ["657251"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 270 271,80"], "Project_Title": ["Application of peptide screening technology for identification of substrates of the Jumonji-C histone demethylases"], "Total_Cost": ["EUR 270 271,80"], "Country": ["United Kingdom"], "Project_ACR": ["RAPID-KDM"], "Technology_Description": "In recent years it has become evident that the functional human proteome is vastly expanded by post-translational modifications (PTMs) that modify protein function and gene expression in a time- and context-dependent manner. Misregulation of these modifications leads to developmental disorders and often contributes to disease biogenesis. However, with the possible exception of protein phosphorylation, the full roles and regulation of these modifications remain poorly understood. Currently, in particular, arginine methylation is proposed to be largely stable and irreversible. Building on my exciting preliminary data that demonstrate that Jumonji C histone demethylases (JmjC KDMs) can catalyse removal of arginine methylation, this proposal aims to identify biologically relevant methylarginine substrates of the JmjC KDM. Cutting-edge mRNA display-based peptide screening technology will be adapted for use as a substrate identification assay in collaboration with Prof Hiroaki Suga at the University of Tokyo. Consensus sequences identified using this novel methodology will be used to identify biologically relevant peptide sequences by bioinformatic searches. On the return to the UK, results with isolated proteins will be correlated with in-cell studies and the functional consequences of these reactions assessed. Given the high level of interest in the post-translational modification field, the results of this study will be of interest to a very wide-range of scientists including other academic researchers in the field of epigenetics and beyond, and major biotechnology and pharmaceutical companies studying JmjC KDMs as drug targets. The fellowship will provide training in state-of-the-art techniques. The collaboration between the University of Oxford and the University of Tokyo will enhance the research capabilities of the European Union, promote cross-fertilisation of knowledge and strengthen research ties with Japan.", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["657292"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["From individual cognition to collective intelligence"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["GROUPCOG"], "Technology_Description": "In many taxa, individuals form groups that collectively process information and make decisions. Through pooling information, these groups can theoretically achieve better decisions than solitary agents. However, it has become increasingly clear that understanding successes and failures of collective decision-making requires a detailed understanding of individual cognitive abilities and of information transfer among group members. I would like to build on my background in social insect collective behavior to investigate a longstanding question in complex systems science: when and how does collective intelligence emerge from individual cognition? I propose to elucidate this issue using novel experiments with homing pigeons\u2013a species that has numerous advantages as a model system. First, pigeons can process information both individually and collectively. When flying alone, each pigeon establishes idiosyncratic habitual routes over time, based on memorized chains of landscape cues. Flocks of pigeons are also collectively able to develop distinctive routes. Thus, I can directly compare the cognitive performance of individuals and groups by giving them the same spatio-cognitive tasks. Second, as pigeons have been among the most important subjects in laboratory experiments on animal cognition, a wealth of data is available on pigeons\u2019 individual cognition. Finally, cutting-edge GPS devices provide high-resolution spatiotemporal data, allowing me to create and validate highly detailed individual-based models. My results will be applicable to multiple research fields, including optimal decision-making theory and collective robotics.", "To": ["2018-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-04-01"], "Project_ID": ["654724"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITY OF GLASGOW"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Electroactive Materials based Bandage for Accelerated Wound Healing"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ELECTRO-HEAL"], "Technology_Description": "Wound healing can be accelerated by using wound dressing impregnated with biochemical agents and biophysical methods such as electrical stimulation (ES). The current ES technology is complex, non-portable, costly and requires external power. ELECTROHEAL is planned to develop a simple, cost effective and disposable wound dressing or bandage to accelerate the wound healing process.", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["753633"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 226 825,20"], "Project_Title": ["Artificial Tissue Actuators by the 3D Printing of Responsive Hydrogels"], "Total_Cost": ["EUR 226 825,20"], "Country": ["United Kingdom"], "Project_ACR": ["DLCHHB"], "Technology_Description": "This proposal describes the 3D printing of hydrogel droplet networks to prepare artificial tissue-like materials that demonstrate stimulus-responsive chemo-mechanical actuation. A recent breakthrough by Prof. Bayley\u2019s research group has enabled the 3D printing of self-supporting droplet networks which can be functionalised to allow rapid electrical and molecular communication along a specific path. As a result of this, an opportunity now exists to prepare tissue-like materials that can perform mechanical work in response to external stimuli. By printing biocompatible and responsive polymer hydrogels into droplet networks, artificial muscles will be prepared that display specific and well-defined motion. The resulting technology will be of great importance for a variety of biomaterial applications, with future European Union (EU) industrial growth as well as the public ultimately benefiting from progress in this area.", "To": ["2017-12-31, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-07-01"], "Project_ID": ["657650"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["FUNDACIO CENTRE DE REGULACIO GENOMICA"], "EU_Contribution": ["EUR 1 274 400"], "Project_Title": ["CRG International Research Postdoctoral Programme"], "Total_Cost": ["EUR 2 548 800"], "Country": ["Spain"], "Project_ACR": ["INTREPiD"], "Technology_Description": "INTREPiD is an innovative 5-year Fellowship Programme that aims at recruiting 12 experienced researchers at the Centre for Genomic Regulation (CRG) located in the Barcelona Biomedical Research Park (PRBB), one of the largest biomedical research clusters in southern Europe. Fellows will be selected following an open, transparent, and merit-based process, based on international peer-review, and offered attractive working conditions in line with the European Charter and Code (the CRG was awarded the HR Excellence in 2013). Selected researchers will be able to develop their own project under the supervision of the group leader they select. They will be offered international, interdisciplinary and inter-sectorial mobility opportunities in a highly creative and dynamic environment supported by cutting-edge core facilities and a vibrant network of collaborators from academia and the private sector. INTREPiD will provide tailored mentoring and a comprehensive training programme, including up-to-date scientific and technological courses in a wide range of topics and disciplines, and modules on transferable skills, entrepreneurship, open science and career development. Mobility to national and international academic and non-academic institutes will be encouraged, in one of the partner organisations or in institutes that research labs collaborate with. Overall, the INTREPiD Programme will provide fellows unique skills and competences for developing a successful career in both the academic and non-academic sector. Thanks to the large CRG network of collaborators locally and internationally, the Programme will also catalyse sharing of best practice in experienced researchers training programmes across different institutes.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-COFUND-2016 - Co-funding of regional, national and international programmes"], "Funding_scheme": ["MSCA-COFUND-FP - Fellowship programmes"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["754422"], "Call_for_Proposal": ["H2020-MSCA-COFUND-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Cost efficient thermal management in motors using next generation nanomaterials"], "Total_Cost": ["EUR 150 000"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["CONDUCT"], "Technology_Description": "Electric motor drives are the universal work horses of industry driving fans, pumps, power tools, compressors and materials handling/conveyor systems. More energy efficient motor designs are needed to meet increasingly stringent EU efficiency standards. Better thermal management of electric motors could make this achievable. Current technologies rely on expensive copper casings or inefficient air cooling. Adding more copper is not feasible (bigger, heavier and expensive) and liquid cooling is not attractive (more energy for circulation/maintenance). The extra mass/volume cannot be easily integrated in compact motor layouts. Removal of heat from small totally enclosed motors is a recurring problem in the food processing, surgical instruments and materials handling where the motors operate at their limits and run very hot. An improved method of cooling could be engineered from advanced materials. Nanomaterials such as carbon nanotubes are at least six times more thermally conductive than conventional thermal interface. A commercial application using specially tailored carbon nanotubes (CNTs) for the development of energy-saving, highly efficient motors is the aim of CONDUCT in partnership with an EU SME motor design/manufacturer. Results of CONDUCT will feed into advanced automotive, consumer, and power electronics industries who also need to find solutions for similar challenges in thermal management.", "To": ["2017-07-31, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2015 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-02-01"], "Project_ID": ["680559"], "Call_for_Proposal": ["ERC-2015-PoC"]}, -{"Partners": ["AARHUS UNIVERSITET"], "EU_Contribution": ["EUR 200 194,80"], "Project_Title": ["The BV Construction: a Geometric Approach"], "Total_Cost": ["EUR 200 194,80"], "Country": ["Denmark"], "Project_ACR": ["BVCGA"], "Technology_Description": "The BRST (Becchi-Rouet-Stora-Tyutin) cohomology plays a very important role in facing the problem of quantizing non-abelian gauge theories via the path integral approach. Indeed, this quantization procedure fails when applied to gauge theories, due to the presence of local symmetries in the action. This problem is overcome by introducing extra (non-physical) fields, defining a so-called BRST cohomology complex. It is precisely this cohomology that allows the recovery of important information on the theory, such as its set of observables or its renormalizability. Despite of its relevance in the context of quantum fields theory, this cohomology still deserves to be fully understood from a mathematical/geometrical point of view. As I discovered in my PhD thesis, a very promising approach to reach this goal is to try to insert the BRST cohomology (constructed following the Batalin-Vilkovisky (BV) approach) in the framework given by Noncommutative Geometry (NCG). In this project I will continue along this line of research by focusing on the case of finite-dimensional gauge theories. Indeed, this context has shown to be surprisingly rich for the analysis of the BV formalism, due to the emergence of a peculiar phenomenon, not appearing in the infinite-dimensional case: the infinite ghosts-for-ghosts. Even though since the discovery of NCG it is known its strong connection with gauge theories, the idea of using NCG as a mathematical framework to formalize the BV construction and the BRST cohomology is still an unexplored territory. The credibility of this approach has been proved by some preliminary results I obtained for U(2)-gauge theories. Moreover, since NCG gives a common tool (the notion of spectral triple) to study both finite and infinite-dimensional gauge theories, the results obtained with this project will be a fundamental starting point for further research: they will point the way to investigate the BV construction also for gauge theories on a 4-dim spacetime.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["753962"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["AARHUS UNIVERSITET"], "EU_Contribution": ["EUR 212 194,80"], "Project_Title": ["Sustaining A Regional Screen Ecosystem In A Small Nation: Aarhus and the West Danish Film Fund, 2002-2019"], "Total_Cost": ["EUR 212 194,80"], "Country": ["Denmark"], "Project_ACR": ["SARSESNA"], "Technology_Description": "Since 2010 Danish screen production has enjoyed international attention with the popularity of high-quality films and TV series. Yet these emerge from a specific culture-political milieu that is concentrated in the capital Copenhagen. Current research on Danish production is similarly Copenhagen-centric. This imbalance means that peripheral regions of Denmark like Aarhus are neglected and underdeveloped as production hubs. This project addresses the question of how regional screen industries of small nations can be sustained and strengthened by examining the site-specific activities of the West Danish Film Fund (DVF) and its collaborations with the Aarhus 2017 EU Capital of Culture project. My main objectives are to 1) produce a 'deep map' of the regional screen ecosystem in Aarhus, 2) identify the implications of new funding and support initiatives, and 3) outline strategies on how regional screen production can productively harness geography, heritage, and tourism to strengthen domestic and international ties. I utilise a combination of qualitative and quantitative methodologies in screen studies to achieve these goals. Through a 4-week secondment at DVF and close links between Aarhus University (AU) and industry players, I will interview screen practitioners and policymakers across the region, examine policy and funding practices, analyse quantitative data relating to production and distribution, and evaluate industry innovations. This project includes both transfer of knowledge to AU and the training of the candidate in advanced techniques. This interdisciplinary research will be the first to significantly deepen knowledge on the regional screen industry of Aarhus and provide policy advice, build networks, concepts and tools on how to sustain the regional screen milieu. Results will have strong applicability to other Capitals of Culture and EU regions, enhancing understanding of how regional screen industries balance national cultural policy with local identity.", "To": ["2020-04-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-05-01"], "Project_ID": ["753597"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Deciphering causes and consequences of inflammation in subtypes of sporadic intestinal cancer"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["DSMT16"], "Technology_Description": "An association between inflammation and carcinogenesis is well established, however, how they are related mechanistically in subtypes of sporadic intestinal tumours remains unclear. This study aims to decipher how oncogenes determine the inflammatory microenvironment (stroma) and how this affects tumour development and survival. Notably, intestinal epithelium-specific expression of oncogenic Kras(G12D), Braf(V637E) and Pik3ca(H1047R) in mice mimics serrated intestinal cancers in humans faithfully. Preliminary data suggest that the mutational make-up of the tumour may dictate the pro- and anti-tumourigenic immune response, which in turn determines tumour development and survival. This study therefore aims to characterise the tumour-infiltrating immune cells by systematic immunophenotyping and to decipher the involved inflammatory signalling mechanisms in a cell-type and mutation-specific manner. Moreover, we aim to reconstruct the formation of the oncogene-specific inflammatory microenvironment, which we will determine via endoscopic transplantation of intestinal organoids derived from Kras(G12D), Braf(V637E) and Pik3ca(H1047R) mice into the large intestine of wild-type mice. Importantly, detection of involved inflammatory mediators and immune cell-subtypes will allow us to genetically target them in vivo using novel in-house generated dual-recombinase systems (DRS). In order to investigate the consequences of inflammation on sporadic intestinal tumourigenesis, models with genetically or experimentally induced chronic inflammation will be applied. Conversely, immunodeficient Rag2;Il2rg\u2013/\u2013 mice will be used to elucidate if sporadic intestinal carcinogenesis in Kras(G12D), Braf(V637E) and Pik3ca(H1047R) mice is dependent on inflammation and can be abrogated. This study will generate new mechanistic insights into the microenvironment of cancer subtypes, which could provide a basis for the development of new personalised immune therapies.", "To": ["2020-02-14, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-02-15"], "Project_ID": ["753058"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ASTON UNIVERSITY"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Optical transmission based on integrability and nonlinear Fourier transform"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["OMICRON"], "Technology_Description": "\"Optical fibre systems form the backbone of global telecommunication networks and carry the bulk of the world's data traffic, serving as a key component of information and communication technology. Although over the years, these systems have become increasingly complex, the quality of optical system performance is still affected by the same key physical features: chromatic dispersion, fiber Kerr nonlinearity, and optical noise. Most of the current optical networks exploit the techniques that were originally developed for linear channels. Thus, it is not surprising that nonlinearity has a detrimental impact on such systems. It has been predicted that, within the next decade the existing optical fibre technology will approach the \"nonlinear transmission limit\", which caps the achievable rate of error-free data transmission. Thus, in order to reach a the higher capacity of optical fibres it is necessary to shift the relevant information and communications technology paradigm by introducing truly nonlinear modulation, transmission, and signal processing techniques. The aim of this project is to develop ground-breaking visionary concepts and approaches to unlock the capacity of fiber-optic communications beyond the limits of current technology by treating optical fiber as the inherently nonlinear medium it is. Our paradigm-shifting approach is based on the concept mathematical notion of integrability and the related nonlinear Fourier transform-type processing of optical signal, which allow us to use of the fibre nonlinearity in a constructive way. This multidisciplinary project, grouping together the mathematical theory of intergability, advanced signal processing, the physics of nonlinear waves evolution, solitons, and noise interaction with nonlinear excitations, combined with the optical transmission methods and purposes, is aimed at the development of fundamentally new communication technologies to satisfy current and future technology challenges.\"", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["751561"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF GLASGOW"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Multi-driver climate change effects on SEAgrass METabolism: ecosystem implications"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SEAMET"], "Technology_Description": "Pressures linked to global climate change (GCC) (i.e. ocean acidification (OA), warming and hypoxia) represent a major threat for marine ecosystems. The single and combined effects of GCC drivers is expected to alter the energetic costs of main metabolic routes, forcing trade-offs in organismal metabolism, with further impacts in the functioning of the whole ecosystem to which they belong. While we have an improving understanding of the impacts of single and paired stressors on individual organisms in the laboratory, to determine real-world impacts of GCC we need to comprehend the impacts of multiple stressors on individuals, understand the acclimation and adaptation processes and assess the repercussion on the ecosystems functioning. SEAMET addresses this major challenge in marine science by assessing if marine communities can survive under the multiple stressor future driven by GCC. SEAMET will use a key benthic habitat-forming species (seagrasses) as model system employing net metabolic balance (NMB) as a functional trait to scale up implications of individual readjustments to GCC on the functioning of the whole ecosystem. It will determine i) the mechanistic basis that regulates C incorporation and photosynthetic physiology, ii) the physiological plasticity and tolerance thresholds of organisms to different combinations of GCC drivers (OA, temperature (T) and hypoxia), and iii) the in situ acclimation and adaptation potential of organisms and associated communities to GCC. SEAMET uses a novel multidisciplinary approach to ensure candidate training and the transfer of knowledge to the host institution. Internationally competitive outputs will be a direct contribution to European MSFD2008/56/EC directive and Horizon2020 strategy for climate action providing novel insights into the effects of climate change on marine ecosystems and their functioning.", "To": ["2020-01-07, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-08"], "Project_ID": ["752250"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE LYON 1 CLAUDE BERNARD"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["NLRP3 in cancer: Deciphering the role of NLRP3 in the DNA Damage response pathway"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["RoNDBioCan"], "Technology_Description": "Cancer represents one of the main causes of death in the European Union (WHO). Particularly, non-small-cell lung cancer (NSCLC) accounts for 85% of lung cancers, and is the leading cause of cancer-related death worldwide. Despite significant therapeutic improvements, the survival rate of patients with advanced stage NSCLC remains dismal, signifying a critical need to elucidate the molecular processes driving NSCLC. Inflammasomes are major drivers of inflammatory responses and are deregulated in a wide range of disorders, yet their participation in carcinogenesis is largely unknown. Genome analyses reported that the NLRP3 receptor, component of the NLRP3 inflammasome, is affected by somatic alterations in 20% of NSCLC. Moreover, recent evidence has shown that NLRP3 is essential for the activation of the ATM/CHK2 pathway in response to double strand breaks (DSBs), while its expression is systematically absent in NSCLC cells. Based on these data, we hypothesize that NLRP3 is a key factor in the DDR pathway to DSBs and in the maintenance of genome integrity in lung epithelial cells, and as a consequence may play a key tumor suppressor role. The objectives of RoNDBioCan will be to decipher the molecular mechanism of NLRP3 function in the DDR pathway and to evaluate the therapeutic potential associated with NLRP3 expression. By characterizing novel NLRP3 partners and examining the impact of NLRP3 re-expression on tumor development in vivo, RoNDBioCan will significantly improve the current knowledge regarding NLRP3 participation in lung cancer. Given that the poor outcome associated with NSCLC is mostly due to limited curative options, there is an urgent need to identify new biomarkers and additional treatments to reduce the current burden of lung cancer. This work will thus considerably contribute to the development of new effective and personalized therapeutic approaches to help improve the prognosis of lung cancer patients.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["751216"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE"], "EU_Contribution": ["EUR 175 419,60"], "Project_Title": ["Quantitative super-resolution optical fluctuation and phase microscopy for structural and functional imaging of Parkinson's disease"], "Total_Cost": ["EUR 175 419,60"], "Country": ["Switzerland"], "Project_ACR": ["funcSOFI-PD"], "Technology_Description": "The changing demographic is one of the greatest challenges in Europe. With an expected 25% of the population over 65 by 2030, the incidence of neurodegenerative age-linked diseases like Alzheimer\u2019s and Parkinson\u2019s is likely to increase. They severely impact quality of life and to date, therapies can only treat the symptoms. Oligomerization and aggregation of the protein \u03b1-synuclein is a hallmark of Parkinson\u2019s disease. Still, the underlying molecular mechanism of cellular dysfunction due to toxic forms of this protein remains unclear. Most studies aiming to uncover \u03b1-synuclein induced neurodegeneration in vivo are using indirect biochemical detection methods. Bridging neurobiology and life science with advanced microscopy and image analysis allows the direct monitoring of Parkinson compromised primary hippocampal neurons. I will combine multi-color 3D super-resolution optical fluctuation imaging with quantitative phase tomography in a multi-plane microscope, to allow structural and fast functional imaging. This innovative imaging concept is used (1) to elucidate \u03b1-synuclein aggregation at the cell membrane and in the cytosol and (2) to uncover the induced cytoskeleton alterations. Ultimately, molecule-specific readout will be complemented by (3) label-free, quantitative phase imaging of membrane dynamics and overall cell morphology at up to 100Hz. I am a biophysicist with a specialization in single molecule spectroscopy and my previous work on photon statistics has led to several high quality publications. This fellowship expands my quantitative microscopy expertise to 3D imaging while enlarging my biologocal scope to neurodegenerative diseases. I will extend my competences by managing the project, following complementary skills courses, and organizing public outreach activities. While performing interdisciplinary research on neurodegenerative disease, I will develop an independent research profile to further enhance the European research landscape.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["750528"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Silicon Cluster based Hierarchical photocatalysts produced by MATrix assembly cluster source"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SCHiMAT"], "Technology_Description": "Photocatalysis is important for solving the worldwide energy shortage and environmental pollution issues. Recently, silicon materials are considered to be promising catalysts. In particular, size controlled Si clusters/nanoparticles/QDs show tunable emissions/absorption from near infrared to blue wavelength, making them promising candidates as photocatalysts. However, the research on the Si clusters based photocatalysts is still slow progress due to lacking of methods of fabrication of Si clusters with precision and in large quantities. In addition, unlike the widely studied Au and Ag nanostructures, which have distinct and well-defined SPR absorption peaks , small (<10nm) Si nanoparticles always exhibit low extinction from the ultraviolet to short wavelength of visible light, and thus result in lower photocatalytic efficiency. In SCHiMAT, the luminescent, photoelectric and photocatalytic properties of Si clusters with precisely controllable size and high production, which produced by \u201cMatrix Assembly Cluster Source\u201d (MACS), will be systemically studied. Based on that, this project will entail the design of a novel kind of hierarchical structure, which involves the choice of spherical semiconductor nanoparticles (SiO2, Al2O3, ZrO2, TiO2 CeO2 and ZnO NPs) and distribution modulation of the Si QDs on the semiconductor support, to largely enhance the photocatalytic efficiency of Si QDs, which is distinct from a conventional photocatalytic efficiency enhancement strategy aimed at exciting surface plasmon by means of incorporating metal nanostructures. This project would open a promising new route to using Si cluster/QDs as visible-light absorber for solar energy conversion. The project combines ER and host supervisor\u2019s expertise in nanocluster, photonics, catalysis research, and will equip the ER to carry out cutting edge research in cluster-based nanomaterials and photocatalysis.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["752102"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF GLASGOW"], "EU_Contribution": ["EUR 269 857,80"], "Project_Title": ["The Social Anthropology of Rabies Epidemiology and Elimination"], "Total_Cost": ["EUR 269 857,80"], "Country": ["United Kingdom"], "Project_ACR": ["SAREE"], "Technology_Description": "Rabies is a viral disease transmitted to humans through the bite of rabid animals, predominantly domestic dogs. It is ranked among the highest priority zoonotic neglected diseases by major international human and animal health organizations (the World Health Organization and World Organisation for Animal Health) and its control is considered a global public good. Although rabies is preventable through administration of post-exposure prohylaxis to individuals exposed to suspect rabid bites and mass vaccination of dogs, the disease still kills thousands globally. India has the highest number of rabies deaths in the world for reasons that are likely to be as much socio-cultural as they are biological, although these factors have neither been investigated nor integrated with epidemiological data. In India, I will focus on two contrasting (based on linguistic, cultural and religious background) rural areas of Gujarat and Maharashtra, where rabies is very prevalent. I will first investigate cultural and religious aspects shaping attitudes towards dogs and local-level acceptance of rabies control and prevention measures, including dog vaccination and human rabies prevention. I will subsequently explore the feasibility and acceptability of in-depth epidemiological data collection tools, contact tracing, to understand cultural and religious influences on people\u2019s health seeking behaviour, practices that may lead to increased rabies risks, and management of these risks within this particular socio-cultural context. Data gathered in this preparatory phase will ultimately inform the design of culturally acceptable and integrated One Health interventions that will to contribute to reduced rabies exposures and mortality. Together with these expected health benefits, my project will demonstrate the added value of One Health, interdisciplinary, approaches to the study and management of zoonoses, and will therefore address an evidence gap of global health relevance.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["751267"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERZITA KARLOVA"], "EU_Contribution": ["EUR 154 720,80"], "Project_Title": ["Evolution and development of pharyngeal pouches and pre-oral gut in basal fishes"], "Total_Cost": ["EUR 154 720,80"], "Country": ["Czech Republic"], "Project_ACR": ["Pharynx2016"], "Technology_Description": "Vertebrates, which include our own species, are the most diverse and successful group of Deuterostomes. Success of this group has been explained by the evolution of elaborated head skeleton adapted to capturing and processing large prey. Most of this skeleton derives from neural crest cells migrating into the pharynx during and after the formation of pharyngeal pouches. To better understand how development of these structures evolved, the research project will study representatives of three basal fish lineages that occupy key positions in jawed-vertebrate phylogeny. It will employ methods of genomics, gene expression, and gene manipulation including CRISPR/Cas9 gene editing system to test a mechanistic model of pouch formation and its relationships to pre-oral endoderm development. The proposal builds upon the Fellow\u2019s research of jawed and jawless vertebrates and bridges a gap in our knowledge of the pharyngeal evolution between the jawed and jawless vertebrates and at the same time between vertebrates and their chordate and deuterostome ancestors. Two-way knowledge transfer is a crucial feature of this project: the Fellow will take advantage of the proficiency of the Supervisor and the Department in embryology, morphology, manipulation, and husbandry of the rare basal fishes and in the genomics and transcriptomics, while at the same time he will transfer his expertise in genetic regulation of development and CRISPR/Cas9 gene editing in non-model organisms to the Supervisor and Host Institution.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Czech Republic"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["751066"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["WISSENSCHAFTSZENTRUM BERLIN FUR SOZIALFORSCHUNG GGMBH"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["CARe in an INterGenerational contextHow do changes in family formation trajectories reflect in later intergenerational relations? A three-generations perspective"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["CARING"], "Technology_Description": "How do changes in early family formation trajectories reflect on later intergenerational relations and care support across generations? Early life choices in the process of family formation reflect in the availability of later potential for care giving, or demands for it. CARING investigates the contribution of early family formation trajectories on explaining differences in intergenerational relations and support patterns later in life. Country differences in the demography of family-linked life stages, and how these reflect on caring responsibilities, have remained largely unexplored. But the timing of family formation and dissolution, childbirth and grand-parenting are key transitions with bearing on entitlements and obligations to inter-household (reciprocal) solidarity and support. To address these issues CARING will explore the effects of family diversification (childlessness, union dissolution and fertility postponement) on intergenerational relations and support in 5 selected countries: Italy, Germany, France, Denmark and Czech Republic. Sequence analysis on data from SHARE surveys will compare family trajectories (partnerships and fertility over 34 years, at ages 16-49) for individuals from the birth cohorts 1927-56. Family formation trajectories will contribute to the study of: current patterns of relations, upward support and downward support through hierarchical multinomial logit models. Results will be validated on fertility trajectories for larger sample sizes and younger birth cohorts (1957-64). The project will adopt a comparative multi-generational perspective with a focus on three generations, helping shed light on the \u2018caring potential\u2019 for the new generations, experiencing longer and thinner (beanpole) families and increasing rates of childlessness. CARING is relevant for the Pillar of Social Rights in the Work Programme and responds to the Europe 2020 strategy objective of an inclusive growth in face of progressive aging in European societies.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["749443"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Investigation of 3D Functional Connectivity in Mouse Visual Cortex using Holography and Optogenetics"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["3DMUCHO"], "Technology_Description": "Cortical neurons respond selectively to sensory features. In mouse visual cortex, convergent evidences point towards stronger connectivity between neurons sharing similar feature selectivity in the superficial layers. The relationship between a three-dimensional (3D) subnetwork, where neurons connect horizontally and vertically to each other, and the functional specificity of individual neurons remain however unresolved. The main objective of this interdisciplinary project is to uncover the 3D functional connectivity in mouse visual cortex in vivo by employing the innovative optical methods pioneered in the host laboratory. Single-cell activation deep into the brain will be, for the first time, enabled using the novel technology of 3D depth-resolved holographic light-patterning and two-photon optogenetics. Combined with whole-cell recordings for measuring postsynaptic responses, precise presynaptic excitation with holography will permit mapping connection pairs within and across cortical planes. Simultaneous presynaptic multi-cell excitation of connecting neurons will test the integration linearity of the postsynaptic neuron. To probe functional connectivity, connection pairs will be examined from a functionally-identified neuronal population, whose tuning specificity to visual attributes is determined using calcium imaging. This fellowship will render me opportunities to acquire a versatile optical toolbox that is of general interest in neuroscience for connectivity mapping and circuit manipulation. Knowledge of local functional connectivity spanning a 3D cortical volume will further provide significant insights into the network mechanism underlying sensory processing.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2017-04-01"], "Project_ID": ["747598"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF STRATHCLYDE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Multi-scale computational hemodynamics in obese children and adolescents: enabling personalised prediction of cardiovascular disease"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["CALLIRHEO"], "Technology_Description": "Childhood obesity is currently at epidemic rates, with serious risks for cardiovascular disease in adulthood and premature death. Obesity is known to accelerate the initiation of endothelial dysfunction and alter the hemodynamics in young arteries. In alignment with urgent EU and worldwide policies on understanding childhood adiposity, we propose to develop a novel and safe computational tool to study numerically, for the first time, the obesity-altered hemodynamics in children and adolescents. The project aims to transfer the non-invasive computational fluid dynamic technology to the paediatric practice and enable personalised prediction of cardiovascular disease and effective decision-making. Within a multi-scale modeling framework, the proposed study seeks to utilise high-fidelity state-of-the-art numerical methods and develop new ones, for the implementation and coupling of the 3D flow in anatomically realistic arterial geometries with macroscopic and microscopic information, ensuring high stability and accuracy of results. In conjunction with clinicians, the study will perform patient-specific numerical simulations, correlated with medical data, and help towards individualized treatment planning, with a significant impact on the quality of life of the young patient. This multidisciplinary perspective is fundamental in elucidating early vascular changes induced by obesity and predict cardiovascular disease risks, while protecting the young population.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["749185"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["OULUN YLIOPISTO"], "EU_Contribution": ["EUR 179 325,60"], "Project_Title": ["Preserving Wooden Heritage. Methods for monitoring wooden structures: 3D laser scanner survey and application of BIM systems on point cloud models"], "Total_Cost": ["EUR 179 325,60"], "Country": ["Finland"], "Project_ACR": ["PresWoodenHeritage"], "Technology_Description": "Wooden Heritage has been recognized today as an object of growing interest in scientific research even on international scale, not only from the architectural point of view but also from theoretical approaches. Over the times many technological systems concerning timber have evolved, refined and defined in the use of mixed solutions. Wooden Architecture represents one of the oldest building systems adopted by the majority of people who developed construction techniques respecting the local traditions. Today this vast and unique wooden heritage needs urgently survey and cataloguing. Fires and abandonment are the main factors jeopardizing the preservation of this architecture; every year too many wooden buildings still disappear because of this negligence. This important challenge has the purpose to obtain new technical methods, procedures and protocols that don\u2019t exist yet, fundamental for technicians and operators. The research project wants to address a new scientific approach on wooden buildings. This is aimed for practical interventions for with respect to the scientific and epistemic foundations, by improving 3D laser scanner survey and photo-modelling activities through post production phases with parameterization of the point cloud to create 3D digital models queried and enriched by informative content and increase BIM (Building Information Modeling) knowledge. The main and most important contribution of this project is the accomplishment of scientific, technical and operational systems and tools for the documentation of wooden structures. During the process of analysis different experts belonging from the best host companies chosen, will guide, check and develop jointly with the applicant all the methods, procedures and theoretical background for achieving the best results in a successful project. In this way the triangle Research-Theory-Practice will offer new insights to timber architecture, to the preservation and maintenance of the wooden heritage.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["746215"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Micro-endoscopes for in-depth high-resolution optogenetics"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["ME-Optogen"], "Technology_Description": "Understanding how the brain works is one of the grand scientific challenges of our times and constitutes a priority research line for the European Union. The study of the brain mechanisms that underlie fear learning and response is particularly relevant as it could provide the key to control anxiety disorders, with an associated high social and economic benefit for the European community.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2017-04-01"], "Project_ID": ["746173"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF KENT"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Understanding children's empathy: an ethnographic study among the indigenous Runa of the Ecuadorian Amazon"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ChildEmp"], "Technology_Description": "The phenomenon of empathy is receiving growing interest in the European public sphere and scientific community. In particular, the question of how one learns to feel empathy towards the environment and the beings which inhabit it has been identified as a key issue to address at this time of environmental crisis.The proposed project investigates how empathy is learnt by children from an Amazonian indigenous community in Ecuador. It explores how and under what circumstances indigenous children in the Ecuadorian Amazon learn to perceive nonhuman entities as human-like and develop empathy towards them. Grounded upon my extended ethnographic knowledge of the region, the project will contribute to broader contemporary debates of how empathy towards nonhumans is culturally acquired, manifested and actively learnt during childhood. This is a social anthropology project with a strong interdisciplinary approach which includes perspectives from developmental psychology, ecology, cognitive science and philosophy. The aims of this project are: 1. to explore how children learn to perceive others as human-like in a setting which is inductive to such learning; 2. to explore children\u2019s perception and understanding of nonhuman personhood and intentionality; 3. to understand the nature of \u2018empathy\u2019 among indigenous Runa people of the Ecuadorian Amazon. These aims will be reached through 10 months of ethnographic fieldwork in an indigenous Runa village where I will deploy participant observation and other methodologies from psychology, medical and visual anthropology which will be designed during pre-fieldwork training at the University of Kent. Research results will be disseminated through an academic and public engagement plan which includes two academic publications, an ethnographic film, a secondment at the Centre for Subjectivity Research in Copenhagen, a workshop and a document to be used by community members for school policy-making.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["746363"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITEIT UTRECHT"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["Global Transitions and Innovation Systems"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["GLOTRAINS"], "Technology_Description": "World development is at a critical turning point. Globalisation has become ever more impactful. At the same time, we see a new long term industrial development cycle (or techno-economic paradigm; TEP) coming into full swing that builds on Information and Communications Technology (ICT) while societies all over the world have to cope with sustainability challenges. These changes lead to a situation where industrial leadership may rapidly shift from one country to another. Europe 2020 reckoned these challenges under its Flagship Initiatives, in particular \u201cAn industrial policy for the globalisation era\u2019\u2019. Drawing on scholarship from the field of Innovation Studies, GLOTRAINS aims to make major contributions to the emerging global innovation system frameworks, combining literatures on industrial catch-up cycles and shifts in global leadership. More specifically, the project aims at further elaborating the Innovation System framework to encompass a globalised and dynamic perspective, while asking whether and how national industrial policy can still play a decisive role. Empirically, this project focuses on both long and short cycle sectors to reflect the two main propositions of the TEP hypothesis, i.e. the sustainability-driven clean-tech sector and the ICT sector. Both involve different types of catch-up mechanisms. Fieldwork cases are organised along a gradient of development stages represented by the countries of Germany, China/Taiwan and Malaysia. The selection of these countries provides an excellent base to examine global catch-up cycles and industrial leadership shifts. The researcher has experience in both transition and catch-up studies, with fieldwork experience in both long and short cycle sectors in China, Taiwan and Malaysia.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["748922"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["SWANSEA UNIVERSITY"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Electrochemical Graphene Sensors as Early Alert Tools for Algal Toxin Detection in Water"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["GrapheneBiosensor"], "Technology_Description": "Episodes of harmful blue algae blooms and the associated algal toxin microcystin-LR (MC-LR) occur frequently in bodies of water worldwide as consequences of eutrophication resulting from anthropogenic activities such as agricultural run-off, urban waste, and manufacturing of detergents and global warming. It had been confirmed that microcystins were responsible for some poisonings of animals and humans where water sources contained toxic cyanobacteria blooms. Microcystins were potent and specific in inhibiting protein phosphatases 1 and 2A (PPl, PP2A). Acute or prolonged exposure to microcystins would cause liver damage, followed by a massive intrahepatic hemorrhage and probably leading to death. In 1998, the provisional guideline concentration limit of 1 \u03bcg/L MC-LR in drinking water was assigned by the World Health Organization (WHO). The development of reliable methods for monitoring MC-LR in water resources is of great interest to determine the occurrence and to prevent exposure to the toxin. Several methods have been developed to detect MC-LR, such as high-performance liquid chromatography/mass spectrometry (HPLC/MS) , bio-, biochemical- and immune-assays, which require long processing times, sophisticated instruments, complex procedures, or high processing cost and are in general used in the laboratory, not in situ. A sensitive, specific, simple, and rapid method for monitoring MC-LR could help to prevent exposure to the toxin. The unique physical and electrochemical properties (e.g., high electrical conductivity, ease of functionalization, high electrochemically active surface area, and broad range of working potentials in aqueous solutions) of graphene make them a candidate material for developing novel and fit-for-purpose electrochemical biosensors/immunosensors as alternatives to the time-consuming, expensive, non-portable and often skills-demanding conventional methods of analysis involved in water quality assessment.", "To": ["2019-09-25, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-26"], "Project_ID": ["743993"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["DANMARKS TEKNISKE UNIVERSITET"], "EU_Contribution": ["EUR 212 194,80"], "Project_Title": ["PRobabilistic PRedictIon for Smart Mobility under stress scenarios"], "Total_Cost": ["EUR 212 194,80"], "Country": ["Denmark"], "Project_ACR": ["PRISM"], "Technology_Description": "PRISM is about designing, implementing and testing methodologies to better predict transport demand in a city. While plenty solutions exist today for this objective, there is general consensus that, under stress scenarios (e.g. large social events, inclement weather, demonstrations, special days), those approaches are insufficient.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["745673"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["Roehampton University"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Barbara Bodichon's Epistolary Bildung"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["BBEB"], "Technology_Description": "Bildung is a controversial German neo-humanist term that, as conceptualised by Wilhelm von Humboldt (1767-1835), proposed a whole new educational project: to bring all the potential contained within each person to full expression as a means towards social progress. Bildung is the object of renewed attention in theories of education today. While it is contested for its classist and sexist bias, it is also reconceptualised as a powerful tool to counterbalance market-oriented instrumentalist uses of education. Seeking to contribute to these debates from the perspective of the history of education, my project will put into play a critical reading of Bildung in order to explore personal correspondence as educational instruments in the life of English feminist, artist and philanthropist Barbara Bodichon (1827-1891). Persuaded of its potential as a thinking tool, reading letters through the lens of Bildung is an original way of exploring epistles as sources of informal education for literate women in nineteenth-century England and an alternative path to review and nuance our understanding of this already studied historical figure.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["746054"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6", "THE UNIVERSITY OF EDINBURGH", "NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU", "TECHNISCHE UNIVERSITEIT DELFT", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE", "SCHLUMBERGER CAMBRIDGE RESEARCH LIMITED"], "EU_Contribution": ["EUR 3 227 952,96"], "Project_Title": ["Waves and Wave-Based Imaging in Virtual and Experimental Environments"], "Total_Cost": ["EUR 3 227 952,96"], "Country": ["France", "United Kingdom", "Norway", "Netherlands", "United Kingdom", "France", "France", "United Kingdom"], "Project_ACR": ["WAVES"], "Technology_Description": "Demand for highly trained scientists with a deep understanding of wave propagation in complex media, and capable of exploiting this knowledge to develop imaging tools for seismology and acoustics, is very high in the Earth and environmental sciences. Wave-based imaging serves to map spatial and temporal variations in the structure of the Earth's interior, of the oceans and atmosphere; it is used to monitor faults and volcanoes and detect natural-resource reservoirs. It is relevant to other disciplines, medical imaging being one of its most widespread applications. Today\u2019s Earth scientists are faced with a set of questions that require the application of wave-based imaging at unprecedented resolution. WAVES aims at fostering scientific and technological advances in this context, stimulating knowledge exchange between seismologists and acousticians, and researchers in the public/private domains. A unique strength of our network resides in the participation of novel physical acoustics laboratories, managed by beneficiaries/partners of WAVES, with a strong record of experimental research on inter-disciplinary and seismology-related topics. WAVES will train young scientists working in academia or industry in how to use this resource effectively, re-introducing the laboratory into the ideas-to-applications pipeline. Experimental work will serve to develop new theory, addressing topics of current interest such as acoustic time-reversal, scattering-based imaging. A truly multidisciplinary network, WAVES will apply these new ideas in a number of contexts: medical elastography is used as a tool to implement novel analogue models of seismic faults; wave sources are localized by a bio-inspired system making use of very few receivers, etc. Through WAVES, a critical mass of expertise will consolidate, defining the study of acoustic/elastic wave propagation and wave-based imaging/monitoring as an independent discipline, rich in applications of intellectual and societal relevance.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["641943"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["THE UNIVERSITY OF SHEFFIELD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Mobility and management of cattle in Iron Age and Roman Netherlands"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["MoMa"], "Technology_Description": "This research project aims to study long-term developments in cattle management and mobility in the Netherlands, from the Iron Age to the Roman period (750 BC \u2013 AD 450). Cattle have always played a crucial role in this region, in supporting arable farming by traction and manure, in providing food in the form of meat and dairy products, and in providing raw materials for clothing and artefacts. Our understanding of cattle management could be improved enormously by an integrated study of traditional and newer methods of research. ", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["740394"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["TECHNISCHE UNIVERSITEIT DELFT"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["Uncovering viral sabotage of host CRISPR-Cas immune systems"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["Anti-CRISPR"], "Technology_Description": "CRISPR-Cas immune system represents one of the most effective weapons against mobile genetic elements in the host defense arsenal. Bacteriophages (phages) armed with anti-CRISPR proteins can, however, inhibit CRISPR immunity by sabotaging components of the immune system with evolutionary advantages. This proposal sets out to discover novel phage-encoded anti-CRISPR proteins and understand the molecular mechanisms of the inhibitory processes.", "To": ["2020-01-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-15"], "Project_ID": ["753528"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["STOCKHOLMS UNIVERSITET"], "EU_Contribution": ["EUR 185 857,20"], "Project_Title": ["Expanding Rights in an Age of Retrenchment: Women, Social Movements and the Politics of Family Leave"], "Total_Cost": ["EUR 185 857,20"], "Country": ["Sweden"], "Project_ACR": ["ERA"], "Technology_Description": "Recent innovations in family policy extend parental leave benefits to fathers and establish paid family leave to care for non-child relatives, such as spouses and parents. Such policies seek to ease work-life tensions, yet there are considerable cross-country differences in the existence, duration and generosity of paid parental and family leave benefits. While welfare state theories offer several explanations for cross-country differences in family policies, we have few explanations for policy content \u2013 who is included and excluded from provisions \u2013 and the timing of policy change.", "To": ["2019-09-03, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-04"], "Project_ID": ["742339"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI PADOVA"], "EU_Contribution": ["EUR 164 203,80"], "Project_Title": ["Novel strategies for anti-HIV-1 therapy: Small molecules targeting RNA partners of the nucleocapsid protein"], "Total_Cost": ["EUR 164 203,80"], "Country": ["Italy"], "Project_ACR": ["BICEPSvsHIV"], "Technology_Description": "European Commission considers HIV/AIDS as a top priority and significantly invests in research devoted to the development of alternative therapeutic strategies leading to new antiretrovirals, which are urgently needed to overcome the emergence of resistance to existing drugs. ", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["751931"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["The molecular mechanism of E. coli FimH pathogenicity"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["FimH-Mech"], "Technology_Description": "Pathogenic bacteria such as E. coli are responsible for a large variety of diseases, including persistent urinary tract and intestinal infections. Their adhesion to the host cell wall is promoted by the binding of FimH located at the tip of the bacterial fimbriae to highly mannosylated cell surface receptors. To resist human defences such as the urinary flow, bacterial adhesion is enhanced under shear force. The shear-force dependence and thus also the pathogenicity of different E. coli strains has been shown to depend on natural sequential variation of the FimH protein. Also probiotic E. coli strains have been shown to attach to host cells, which raises the question as to why these bacteria evoke a beneficial effect upon their host. ", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2017-04-01"], "Project_ID": ["750280"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Towards a molecular understanding of the centriole assembly process"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SAS6-Cep135-CPAP"], "Technology_Description": "The centriole is a conserved organelle essential for cell organisation, division and motility through its capacity to organise microtubules. A broad range of human diseases, such as microcephaly and cancer, have been associated with defects in centriole formation, making the full characterisation of its assembly process of great interest. Centrioles are miniature cylinders of characteristic symmetry, diameter and length, yet the molecular methods by which these parameters are defined are only partly understood. The objective of this proposal is to study the structure \u2013 function relationship of the centriolar proteins SAS-6, Cep135 and CPAP, which together form a protein interaction network that supports centriole elongation and connects the core centriole scaffold with its microtubule-based exterior. This project will be carried out through an integrated, multi-disciplinary approach combining structural biology, biophysics and functional assays in human cell lines. We will investigate the effect of disease-causing mutations in the structure and function of the SAS-6 \u2013 Cep135 \u2013 CPAP network. This work will boost our understanding of the centriole formation process and how it is perturbed in disease, and be a pioneering example of elucidating the molecular architecture of a cell organelle.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["752069"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Microrheology of two-dimensional active colloidal crystals and glasses"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["MicACol"], "Technology_Description": "Self-propelling colloidal particles, originally designed to mimic living microorganims, offer exciting opportunities to engineer smart materials equipped with activity. To date, the behavior of synthetic microswimmers has been extensively studied in homogeneous environments, close to confinements and in semi-dilute suspensions. However, for materials\u2019 design, the use of solid-like phases, such as crystals and glasses, is highly desirable. While recent numerical simulations have invested a lot of effort in understanding the structural and mechanical properties of dense colloidal materials with activity, experiments significantly lag behind. One difficulty stems, for instance, from the presence of short-range attractive forces that affect the active motion when two of more microswimmers come near contact. ", "To": ["2019-09-03, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-04"], "Project_ID": ["747029"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 144 230"], "Project_Title": ["Revitalizing the clinical potential of type I IFNs in fighting influenza A virus infections with AcTaferon."], "Total_Cost": ["EUR 144 230"], "Country": ["France"], "Project_ACR": ["AcTaferon"], "Technology_Description": "Based on their antiviral and antitumor effect, type I interferons (IFNs) were believed to be the miracle drug to tackle viruses and cancer. However, clinical IFN applications remained limited due to severe side effects resulting from widespread cellular sensitivity to IFN, which limits the administrable doses. Hence, the drug concentration at the desired infection or tumor site is often too low to be fully therapeutic efficient. AcTaferon (Activated-by-Targeting interferon), co-developed by Prof. Uz\u00e9, circumvents these obstacles. By fusing an IFN mutant with strongly reduced receptor binding affinity to a targeting moiety that recognizes a surface marker on specific cells, AcTaferon remains inactive \u201cen route\u201d through the body and unveils its biological activity only on specific target cells. Robust tumor regression without side effects and preliminary antiviral effects underscore the huge clinical potential of AcTaferon to fight cancer and viral diseases. By combining the AcTaferon and influenza expertise of Prof. Uz\u00e9 and Prof. Saelens, respectively, this interdisciplinary project offers the opportunity to broaden the innovative AcTaferon therapeutic strategy from the cancer to the viral infection field. Influenza A was selected as a pilot target as seasonal influenza A epidemics and occasional pandemics remain a serious health threat causing substantial morbidity and mortality. Influenza A-targeted AcTaferons will be developed and analyzed in relevant in vitro and in vivo models. Eventually, all knowledge will be transferred to Orionis, a company that will implement the AcTaferon technology to develop novel drugs. My background on the intracellular processes that negatively regulate cytokine receptors and hence influence the cellular sensitivity to a (therapeutic) cytokine is an asset to this project. I will be able to extend my fundamental research experience with applied cytokine research, which may extend into a new academic or industrial research pipeline.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2017-05-01"], "Project_ID": ["753112"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE QUEEN'S UNIVERSITY OF BELFAST"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Water and Baptism in Old English Poetry"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["Cleansing Water"], "Technology_Description": "The purpose of this project is to offer the first comprehensive study of the function of water and its relationship with baptism in the four most significant Old English poetry manuscripts: the Exeter Book, the Vercelli Book, the Junius XI and the Cotton Vitellius A XV. ", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["744615"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Algebraic Group Actions in Geometry, Arithmetic, and Physics"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["AGAGAP"], "Technology_Description": "\"Geometry, arithmetic, and quantum physics historically have had many points of intersection. This project will use recent techniques in algebraic group actions, especially those of Kirwan, to address problems of overlapping interest to distinct research groups at the University of Oxford \u2013 Algebraic Geometry, Number Theory, Mathematical Physics, and the Centre for Quantum Mathematics and Computation. ", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["742052"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI PADOVA"], "EU_Contribution": ["EUR 180 277,20"], "Project_Title": ["Combining Remote Sensing Technologies for Peatland Detection and Characterization"], "Total_Cost": ["EUR 180 277,20"], "Country": ["Italy"], "Project_ACR": ["CReScenDo"], "Technology_Description": "CReScenDo aims at quantifying the extent and thickness of peatlands from the local to the regional scale, to accurately define their importance in the global carbon cycle. Peatlands are extraordinary reservoirs of organic carbon (almost matching, according to some estimates, the atmospheric carbon pool), which is currently being released into the atmosphere due to a number of often anthropogenic degradation processes (e.g. soil drainage, fires, etc.). The conservation of peatlands is therefore a key measure to reduce CO2 emissions and to mitigate climate change (e.g. according to the Intergovernmental Panel on Climate Change). However, regional and global estimates of peat deposits remain highly uncertain and an effective quantification methodology is still missing, negatively impacting our ability to plan effective conservation strategies. The innovative approach proposed by CReScenDo combines passive and active satellite remote sensing and geophysical data collected from airborne platforms to map extent and thickness of peat deposits at regional scale. The proposed methodology will yield a set of integrated observations providing the first large-scale picture of the relations among peat deposits, geomorphological features, and soil and environmental characteristics. Three peatland areas (two in Europe and one in Asia) are selected to implement and test the methodology, using field observations to improve the accuracy and quantify the uncertainty. The ability of the methodology to characterize/classify different peat types will also be tested and used to map the carbon pool stored at the three study sites. The applicant has a solid background in optical remote sensing and ecological modelling applied to salt-water wetlands. The hands-on training performed at the host institution and at a private company (Secondment) will provide her with new scientific competences in topographic and geophysical data analysis tools with tremendous impact on her mid/long-term career.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["747809"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Operando FTIR spectro-electrochemistry of hydrogenases: unraveling the basis of biological H2 production for innovative clean energy technologies"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["H2Bio2Energy"], "Technology_Description": "Ongoing search for renewable energy technologies is essential in Europe to tackle the continuous increase in demand and the environmental and ethical concerns. Hydrogen is a promising renewable fuel, but so far its production is not clean as the conventional industrial techniques start from fossil fuels. Production of H2 by biological, biotechnological or bioinspired methods would solve this problem and the study of FeFe-hydrogenases is a key step in this process. For this reason, the proposal is well aligned with the EU Societal Challenges in \u201cSecure, clean and efficient energy\u201d. FeFe-hydrogenases are efficient metalloenzymes that catalyse H2 production from water at high turnover rates, using Fe, rather than Pt active sites. Building on my previous experience with these enzymes, in this project I will apply a highly innovative approach to investigate how nature uses cheap iron to catalyse H2 production. Protein film infrared (IR) electrochemistry was recently developed by Prof Vincent at the University of Oxford, allowing electrochemical triggering of enzyme catalysis with simultaneous IR spectroscopic study of how the enzyme works. This will provide a deep understanding of enzyme structure/function relationships, from coordinated electron and proton transfer to structural rearrangements at the Fe site. Due to my prior expertise in FeFe hydrogenases which are not studied in the host group, and Oxford\u2019s excellence in bio-spectroscopy, the Fellowship will promote exceptional bidirectional knowledge transfer. Dissemination of research through Oxford\u2019s outreach programs will increase the impact of the project to varied audiences. Access to the well-established training and career development activities in Oxford, and the world-class programs of visiting speakers, will advance my career as I gain new knowledge and skills, enhance my scientific profile by acquiring international experience, expand my scientific horizon, strengthen my skills, and build new networks.", "To": ["2020-02-29, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["752305"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Quantum Systems Investigated through Tensor Network States"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["quasiTENS"], "Technology_Description": "Tensor Network States (TNS) are a class of variational wave functions whose number of parameters can be increased systematically in order to improve the accuracy of the approximation. In effectively one dimensional systems, such as certain magnetic insulators, TNS reproduce the macroscopic properties of the ground state by 1 part in 10 million. TNS are expected to eventually give rise to similar accuracies in higher dimensions, though, in this case, their numerical implementation is much more sophisticated.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["749150"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Engineering Electron-Phonon Interactions of Two-Dimensional Materials from First-Principles"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["EPIC2D"], "Technology_Description": "Two-dimensional (2D) materials such as graphene and transition metal dichalcogenide monolayers receive a tremendous amount of attention because of their extraordinary properties and application potential. Electron-phonon interactions, which couple the electronic and lattice vibrational degrees of freedom in solids, affect a wide range of material properties, for example lattice stability and carrier mobility. Importantly, the strength of electron-phonon interactions in 2D materials can be tuned to a significant extent by electric field doping and elastic deformation, opening up the possibility of rational engineering of electron-phonon interactions in 2D materials.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["743580"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["JOHN INNES CENTRE"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["How do pathogens exploit the symplast to promote disease?"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["HOPESEE"], "Technology_Description": "It is well established that pathogens invade plant cells to establish an infection. Part of a biotrophic pathogen\u2019s infection strategy is to secrete effectors into host cells in order to manipulate host processes to the pathogen\u2019s benefit. It has been observed that some effectors can move from cell-to-cell in the host and this suggests that a pathogen can invade and exploit cells surrounding the immediate infection site. To further support this hypothesis, my host lab observed that PAMP-induced plasmodesmata (PD) closure is suppressed in some virulent infections, suggesting pathogens attempt to keep intercellular connections open; some pathogens must maintain intercellular symplastic connectivity by counteracting PAMP-induced PD closure to promote disease. This proposes the question: why does a pathogen want PD open? We hypothesise that open PD allow pathogen effectors to move into non-infected cells where they targeting host processes to promote infection and allow pathogen access host resources such as sugars. In this study, I will use the Hyaloperonospora arabidopsidis\u2013 Arabidopsis interaction to identify cell-to-cell mobile effectors and their host targets. I will identify global changes of host gene regulation that are associated with cell-to-cell mobile effectors and examine the effect of cell-to-cell mobile effectors on sucrose transport around an infection site. The results will give insight into how pathogens exploit the symplast and non-infected cells to promote infection, characterising a poorly considered element of plant-pathogen interactions.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations"], "From": ["2017-04-01"], "Project_ID": ["749755"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Energy-generating synthetic tissues"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ENERGSYNTISSUE"], "Technology_Description": "Synthetic tissues are of great scientific and technological importance as they might not only enable purpose-driven complementation of natural tissue functionalities to repair or replace dysfunctional or damaged tissues, but also allow the engineering of intelligent artificial biomaterials with features that do not exist in nature. Main limitations of current synthetic tissues based on lipid-coated droplet networks are a low material durability over the long-term, a low availability of diverse functions (apart from electrical communication and macroscopic deformation) and a lack of control capacity using external signals in a reversible manner. The main goal of this proposed project is the engineering of a novel light-controllable synthetic tissue capable of generating energy, which consists of a printed network of polymer-coated droplets that carry specific enzymes within distinct droplets. Such energy-generating synthetic tissues convert chemical energy into electrical energy, and might therefore be applied as miniature bio-batteries to power implanted medical devices such as pacemaker in human patients. Engineering of synthetic cells and bio-batteries are a current focus of the 2017 Work Programme of European Commission and will advance the development of industrial biotechnology, which is one of Key Enabling Technologies of European industrial policy.", "To": ["2020-04-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-05-01"], "Project_ID": ["750801"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["POLITECNICO DI TORINO", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "UNIVERSITAET STUTTGART", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "ECOLE CENTRALE DE LYON", "MIDDLE EAST TECHNICAL UNIVERSITY", "TECHNISCHE UNIVERSITAET MUENCHEN", "BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION", "VYSOKA SKOLA BANSKA - TECHNICKA UNIVERZITA OSTRAVA", "CRAY UK LIMITED", "MAVEL AS"], "EU_Contribution": ["EUR 3 815 947,44"], "Project_Title": ["models, EXperiments and high PERformance computing for Turbine mechanical Integrity and Structural dynamics in Europe"], "Total_Cost": ["EUR 3 815 947,44"], "Country": ["Italy", "United Kingdom", "Germany", "United Kingdom", "France", "Turkey", "Germany", "Spain", "Czech Republic", "United Kingdom", "Czech Republic"], "Project_ACR": ["EXPERTISE"], "Technology_Description": "Energy and Mobility are two primary driving forces in the 21st century. Development of incremental and disruptive technologies will have key impacts on the world\u2019s societies, and on safety, security and competitiveness of Europe. Amongst those technologies, gas turbines will play a major role. Recovery of shale gas depends decisively on compressors. Modern gas supplied power plants are bridging towards the age of renewable energies. Aeroengines are to undergo the most massive changes in their history with the advent of composite materials, gear boxes, and turbine-electric concepts separating generation of power and thrust. A technological commonalities of the upcoming challenges is the need for full model based development and computer system simulation.", "To": ["2021-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-03-01"], "Project_ID": ["721865"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH"], "EU_Contribution": ["EUR 187 419,60"], "Project_Title": ["Closing in on New Physics in light-quark flavour transitions: from tau decays to the LHC"], "Total_Cost": ["EUR 187 419,60"], "Country": ["Switzerland"], "Project_ACR": ["Tau-SYNERGIES"], "Technology_Description": "This action studies the synergy of the Energy and the Intensity Frontiers, with the focus on non-standard effects involving leptons and light quarks. The project starts with an unprecedented Effective-Field-Theory (EFT) analysis of hadronic tau decays including non-standard effects. Their discovery potential and complementarity with direct LHC searches will be assessed in a model-independent approach. The results will be combined with d(s)\u2192u l nu (l=e,mu) transitions and eq \u2192 eq (q=u,d,s) processes in a comprehensive EFT flavour fit that will close in on New Physics involving leptons and light quarks.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Research Organisations"], "From": ["2017-07-01"], "Project_ID": ["745954"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "JANSSEN CILAG SA"], "EU_Contribution": ["EUR 1 341 024,48"], "Project_Title": ["Late Stage Fluorination and its Applications to Drug Discovery"], "Total_Cost": ["EUR 1 341 024,48"], "Country": ["United Kingdom", "Spain"], "Project_ACR": ["FLUDD"], "Technology_Description": "All of modern medicine is dependent on advances in chemistry and the healthcare goalposts have moved as the century has progressed. The pressing need to shorten cycle times and reduce the costs of drug discovery has led pharma and the clinicians that guide them to use scanning techniques such as positron emission tomography (PET), enabling them to increase disease understanding, study target engagement with therapeutics and improve decision making, so that only the best candidate molecules progress to the later stages of drug development. Overcoming these challenges requires multidisciplinary knowledge, and can be facilitated through stronger links between academia and Pharma. Chemical entities substituted with fluorine or fluorine-containing groups are frequently used to design drugs with improved pharmacological and pharmacokinetic profiles that provide important benefits over existing therapies, such as superior safety, efficacy, dosing, and patient compliance. Furthermore, 18F is often selected as the preferred positron-emitting isotope for the labeling of PET tracers due to its advantageous properties. The scientific objective of FLUDD is to develop novel late stage fluorination chemistry to populate the chemical and radiochemical space available for drug discovery with a focus on novel fluorine-containing fragments, molecules and biomolecules that are not directly accessible from commercial sources or the scientific literature. These novel methodologies will be applied to drugs and diagnostics discovery using both small molecules and proteins. The educational objective is to train the next generation of doctoral scientists in the practice of chemical synthesis and radiochemical methods with an in-depth appreciation of their applications in medicine. FLUDD objectives will be met with a novel Oxford-Janssen Alliance augmented with leading partners from academia, industry and the clinic.", "To": ["2021-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-03-01"], "Project_ID": ["721902"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["KING'S COLLEGE LONDON"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Greek Identity in Art Music since the Early Nineteenth Century: Towards an Interdisciplinary Methodology"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["GRIDAMUS"], "Technology_Description": "This project is the first large-scale, interdisciplinary attempt to study mechanisms of national identity construction through modern Greek (post-1830) art music. It has two primary objectives: a) to develop an interdisciplinary methodological framework for the analysis of Greek art music drawing on historical musicology, Modern Greek Studies and ethnomusicology; and b) to offer a revisionist study of Greek art music \u2013 a repertory that remains to be investigated in the depth it merits \u2013 by exploring the ways in which it has mediated Greek identity during the period since the formation of the Greek nation-state in the early 19th century. Traditionally, the issue of \u201cGreekness\u201d \u2013 a perceived national character or identity \u2013 in music has been analysed with respect to the question of the assumed \u201ccontinuity\u201d of Greek history and culture since antiquity, as well as a quest for authenticity, purity, loyalty and uniqueness. Yet, such treatment of national identity is essentialising and self-exoticising. Recent scholarship on Greek music is starting to recognise the usefulness of contemporary methods of historical and cultural contextualisation. These approaches have much to gain from dialogue with a) recent critical discourses developed to understand and contextualise the concept of \u201cGreekness\u201d within modern Greek studies and b) ethnomusicological approaches to the study of music and identity. This project will equip me to become the first specialist on Greek art music to use an interdisciplinary methodology for the analysis of this music that draws on historical musicology, modern Greek studies and ethnomusicology, a method that has the potential to become paradigmatic for the study of other national repertories too and useful for other disciplines. The research will exploit archival sources while also drawing upon ethnographical methods. The outcomes will be: 1) a monograph, 2) two conference papers, 3) a series of public lectures and 4) a seminar series.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["745631"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Detection of biocontrol agents from casing material to inhibit mushroom mycoparasites through casing microbiome characterization and Raman spectroscopy of isotopically labelled organisms."], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["MYCOBIOME"], "Technology_Description": "Mycoparasites cause significant crop losses in the cultivated mushroom Agaricus bisporus, but as fungal pathogens of cultivated fungi pose major challenges for disease control. The casing layer used to cover mushroom compost supports a diverse community of microorganisms with potential to act as host-specific biocontrol agents capable of inhibiting the germination or growth of mycoparasitic fungi, while even promoting mushroom development. In this project we propose to apply novel and state-of-the-art techniques to characterize the casing microbiome along the crop cycle and identify potential biocontrol agents to control bubble diseases by amending casing with a stable synthetic microbial ecosystem. High-throughput community analysis, developed by the host group and used for the characterization of the plant microbiome, will be implemented to analyse the complete community structure of a suppressive casing material. Target materials will be selected through pilot trials conducted within the Partner Organization (PO) facilities. Potential antagonistic bacteria will be valuated to detect and isolate biocontrol agents through isotopic labeling of fungi (a new protocol for labeling spores and hyphae will be developed) and Raman-confocal microspectroscopy. Potential biocontrol agents will be finally tested in a pilot trial. The project builds a consortium formed by two European institutions, including certain departments from the academic host institution (University of Oxford, UK) and one non-academic PO (ASOCHAMP RIOJA, Spain), a research centre with extensive experience analysing casing materials and mycoparasites. It has been designed to augment and complement the research and transferable skills sets of the Marie Curie fellow and will greatly enhance his career prospects accordingly. Through the training and the research results arising, the Fellowship will be beneficial to the fellow, the host institution, the PO, the mushroom industry and the European society.", "To": ["2019-03-12, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-03-13"], "Project_ID": ["742966"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["The Digest and the Exploitation of the Countryside in the Western Roman Empire (2d cent. BC-3rd cent. AD).Evidence of the water control"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["DEXCORE"], "Technology_Description": "Every aspect of the ancient world depended on the control and exploitation of the countryside, but scholars have until recently failed to engage with an abundant and detailed material on the subject: the legal texts of the Digest. The thought of the Roman jurists constituted a powerful model for all the minor and local institutions and legal documentation reveals not only rules, but also actual practices and issues of unquestionable historical interest. Amongst the significant amount of legal texts concerning the countryside, the issues of water sharing and that of erosion and flood risks management are particularly well represented, constituting a key element of an essential aspect of the ancient economy, i.e. the agricultural production. However, an overall underestimation has led to a serious insufficiency of methodology concerning these texts, an evident obstacle to its exploitation in a historical perspective. This research proposes to demonstrate how relevant the study of Roman law is for our knowledge of the Roman countryside, by confronting the strikingly unexplored jurisprudential documentation with more traditionally exploited archaeological and environmental sources. The focus on water control is motivated by a will to concentrate on a crucial condition of the exploitation of the countryside, which has raised sufficient interest from the ancient jurists themselves, as well as from the scholars in the past decades, so as to generate enough primary and secondary sources for us to consider. The objective is twofold: first, to establish a clear and consistent methodology for the historical study of the jurisprudential sources; second, to apply it to case studies in order to produce new insights into a fundamental issue of the Roman world.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["742523"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 223 152,92"], "Project_Title": ["The Curiosity Carnival: Oxford European Researchers\u2019 Night 2017"], "Total_Cost": ["EUR 407 172"], "Country": ["United Kingdom"], "Project_ACR": ["Curiosity Carnival"], "Technology_Description": "By capitalising on the University of Oxford\u2019s world-class European-funded research base, together with our outstanding museums, libraries, gardens and woods, education programmes and public engagement expertise, we will create a truly inspirational multi-venue multi-disciplinary European Research night in 2017 on the theme of \u2018People and Planet'.", "To": ["2017-12-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-NIGHT-2016 - European Researchers' Night"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["722615"], "Call_for_Proposal": ["H2020-MSCA-NIGHT-2016"]}, -{"Partners": ["TECHNISCHE UNIVERSITEIT EINDHOVEN", "CHALMERS TEKNISKA HOEGSKOLA AB", "AALTO-KORKEAKOULUSAATIO", "KATHOLIEKE UNIVERSITEIT LEUVEN", "THE UNIVERSITY OF LIVERPOOL", "LEVEL ACOUSTICS BV", "MATELYS - RESEARCH LAB", "MATERIALISE NV", "SIEMENS INDUSTRY SOFTWARE NV", "MOELVEN TOREBODA AB"], "EU_Contribution": ["EUR 3 907 082,88"], "Project_Title": ["A sound fundament for our future buildings"], "Total_Cost": ["EUR 3 907 082,88"], "Country": ["Netherlands", "Sweden", "Finland", "Belgium", "United Kingdom", "Netherlands", "France", "Belgium", "Belgium", "Sweden"], "Project_ACR": ["Acoutect"], "Technology_Description": "To ensure a healthy environment for people living and working in buildings, research and engineering in the area of building acoustics is essential. Developments in modern building concepts, such as sustainable low-energy consuming buildings, buildings with lightweight materials and open plan working environments, as well as the need to build in extremely noisy areas, require involvement of acoustic experts in order to successfully (re)design buildings without negatively impacting upon people\u2019s health and well-being. Taking up current and future acoustic challenges requires innovative solutions based on a thorough understanding and mastering of modern methods and tools, as well as a holistic acoustic approach involving acoustic design, products and subjective evaluation. However, in the complex field of building acoustics, research activities typically are not holistic and have become slightly marginalised. As a consequence, there is a lack of building acoustics experts.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["721536"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["FUNDACIO PRIVADA INSTITUT CATALA D'INVESTIGACIO QUIMICA", "FUNDACIO PRIVADA INSTITUT CATALA D'INVESTIGACIO QUIMICA"], "EU_Contribution": ["EUR 149 750"], "Project_Title": ["Late-stage catalytic carboxylation techniques with labelled carbon dioxide: new opportunities for radiolabelling"], "Total_Cost": ["EUR 149 750"], "Country": ["Spain", "Spain"], "Project_ACR": ["LABEL-DIOX"], "Technology_Description": "Absorption, distribution, metabolism and excretion\u00b4s studies (ADME) are essential for drug discovery and development, providing invaluable preclinical data to understand how the drug behaves in living organisms, thus allowing to make a decision on whether the drug should be terminated or advanced to the next step. At present, most of these studies are performed with a radiolabelled 14C-labelled version of the drug; unfortunately, current radiolabelling syntheses rely on lengthy-step sequences or rather expensive 14C-labelled building blocks, dramatically raising the costs for the research and development, and delaying the execution of preclinical studies. Taking into consideration that carboxylic acids are privileged motifs in a myriad of agrochemicals or pharmaceuticals, LABEL-DIOX offers the opportunity of promoting a late-stage carboxylation event with labeled CO2. The protocol is user-friendly, with components that are neither air- nor moisture sensitive, utilizes earth-abundant catalysts and operates under mild conditions. LABEL-DIOX will increase the overall efficiency of the carbon isotope incorporation, reduce the costs that would have resulted from the design of a lengthy radiolabelled synthesis, minimize the costs for waste disposal and dramatically increase the revenues, thus changing the way industrial chemists conduct radiolabelling of drugs containing carboxylic acids.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-12-01"], "Project_ID": ["755251"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["UNIVERSIDAD COMPLUTENSE DE MADRID", "UNIVERSIDAD COMPLUTENSE DE MADRID"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Automated tools for atomic resolution mapping of electrostatic fields in the electron microscope"], "Total_Cost": ["EUR 150 000"], "Country": ["Spain", "Spain"], "Project_ACR": ["POLAR-EM"], "Technology_Description": "The overarching goal of this proposal is to produce a software tool that will allow inexpensive atomic resolution mapping of electrostatic potentials and fields within materials in the electron microscope. Such mapping capabilities could revolutionize our understanding of future materials for devices based on exploiting functionalities such as ferroelectric polarization. During the last decade, the scientific community has addressed this pressing need by developing microscopy techniques sensitive to the local potential such as the recently reported differential phase contrast (DPC) imaging technique. DPC can, for the first time, map the distribution of electrostatic potential and field within a material in an atomic column-by-atomic column fashion in a direct way. However, DPC imaging relies on the use of non-flexible segmented detectors with non-linear geometries. The increasing degree of physical complexity has made this approach rather unaffordable for a conventional materials research lab composed of non-specialists. The technology we propose here will replace such detectors by software tools and produce similar atomic resolution maps. The key idea is to acquire electron diffraction images with more conventional detectors and then apply post-acquisition analysis routines. Pixelated detectors (i.e., cameras) will be used to record the variation of the electron diffraction pattern as a function of probe position. Imaging configurations similar to DPC will be chosen after acquisition: a given detector geometry can be reproduced off-line by partial, ad-hoc integration of regions of the electron diffraction pattern over at each probe position. Basic mathematical operations between images ensuing form those different regions of the bright field disk will produce a DPC image in a straightforward manner. Such a technology will outsmart complex non-flexible hardware only by inexpensive software routines working on the new generation of ultra-fast cameras.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["754735"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["FUNDACIO INSTITUT DE CIENCIES FOTONIQUES", "FUNDACIO INSTITUT DE CIENCIES FOTONIQUES"], "EU_Contribution": ["EUR 2 748 437"], "Project_Title": ["Topological nano-photonics"], "Total_Cost": ["EUR 2 748 437"], "Country": ["Spain", "Spain"], "Project_ACR": ["TOPONANOP"], "Technology_Description": "One of the most fascinating phenomena in nature is the interplay between quantum mechanics and the flow of electrons in solids. A tangible example is the quantum hall effect, where electrons flow with virtually zero dissipation. That is because electrons can flow only in one direction, which makes them move around objects without scattering, representing robustness by topological protection. Essential for this effect is the magnetic field that breaks time-reversal symmetry.", "To": ["2022-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-11-01"], "Project_ID": ["726001"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["TECHNISCHE UNIVERSITEIT DELFT", "TECHNISCHE UNIVERSITEIT DELFT"], "EU_Contribution": ["EUR 1 998 985"], "Project_Title": ["Signal Transduction in Organic Materials"], "Total_Cost": ["EUR 1 998 985"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["STORM"], "Technology_Description": "It is the overall aim of this project to use responsive catalysts to introduce signal transduction cascades in soft materials, enabling autonomous, programmable and amplified response of soft materials to chemical signals from their environment. 'Smart' soft materials could find many important applications ranging from personalized therapeutics to soft robotics. However, as most molecular materials are unable to communicate, or even respond to, changes in their environment, truly smart materials are still far out of reach. Signal transduction is one of the primary processes used by living cells to react to events taking place in their environment, often involving a signal triggering enzymatic activity, leading to a cellular response. Such rudimentary communication is entirely non-existent in synthetic materials. I here propose the introduction of catalysis-based signal transduction between chemical systems to enable synthetic materials to respond autonomously to events taking place in their environment. Key to achieving this objective will be the development of switchable catalysts, using signals originating from chemical events to change catalytic activity, and coupling changes in catalytic activity to responses in soft materials. In achieving these objectives, I will develop new design strategies for responsive soft materials, enabling control over material formation and response in time and space, through autonomous reaction to chemical signals. This will allow the development of new actuators, self-healing materials, sensors, therapeutics and self-regulation and self-correction of material assembly. It will also constitute an entirely new role for catalysis, as catalysis will be engaged to constitute a first step towards achieving communication between artificial chemical systems.", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["726381"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["RIJKSUNIVERSITEIT GRONINGEN", "RIJKSUNIVERSITEIT GRONINGEN"], "EU_Contribution": ["EUR 1 999 970"], "Project_Title": ["Design and Engineering Next-Generation Nanopore Devices for Bioplymer Analysis"], "Total_Cost": ["EUR 1 999 970"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["DeE-Nano"], "Technology_Description": "Nanopores have emerged in the past few years as a promising analytical technique. The basic concept of nanopore sensing is to apply a potential across individual nanoscale pores and observe the disruption of the ionic flow caused by single molecules entering the pore. Ionic currents through protein pores have been successful at recognizing tiny differences in molecules in solution. Most notably, arrays of thousands of nanopores integrated in low-cost and portable devices are now capable of sequencing DNA at the single-molecule level. The main challenge of nanopore sensing is the inability of controlling the protein pore diameter and geometry, which determines the signal and enables selectivity based on physical size.", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["726151"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITY OF SOUTHAMPTON", "UNIVERSITY OF SOUTHAMPTON", "UNIVERSITAET ROSTOCK"], "EU_Contribution": ["EUR 1 455 590"], "Project_Title": ["Bayesian Agent-based Population Studies: Transforming Simulation Models of Human Migration"], "Total_Cost": ["EUR 1 455 590"], "Country": ["United Kingdom", "United Kingdom", "Germany"], "Project_ACR": ["BAPS"], "Technology_Description": "The aim of BAPS is to develop a ground-breaking simulation model of international migration, based on a population of intelligent, cognitive agents, their social networks and institutions, all interacting with one another. The project will transform the study of migration \u2013 one of the most uncertain population processes and a top-priority EU policy area \u2013 by offering a step change in the way it can be understood, predicted and managed. In this way, BAPS will effectively integrate behavioural and social theory with modelling.", "To": ["2021-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["725232"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["INSTITUTE OF EXPERIMENTAL MEDICINE - HUNGARIAN ACADEMY OF SCIENCES", "INSTITUTE OF EXPERIMENTAL MEDICINE - HUNGARIAN ACADEMY OF SCIENCES"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Microglial control of neuronal activity in the healthy and the injured brain"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Hungary", "Hungary"], "Project_ACR": ["MicroCONtACT"], "Technology_Description": "Microglia are the main immune cells of the brain, but their role in brain injury is highly controversial due to the difficulties in selectively manipulating and imaging microglial actions in real time. Specifically, it is unclear whether microglia control neuronal survival after injury via shaping the activity of complex neuronal networks in vivo. To this end, we have combined fast in vivo two-photon imaging of neuronal calcium responses with selective microglial manipulation for the first time. Our data suggest that microglia constantly monitor and control neuronal network activity and these actions are essential to limit excitotoxicity and neuronal death after acute brain injury. We also identify microglia as key regulators of spreading depolarization in vivo. However, the underlying mechanisms remained unexplored. Here, I propose that microglia control neuronal excitability and based on preliminary data I set out to investigate how this occurs. We will combine selective, CSF1R-mediated microglia depletion with advanced neurophysiological methods such as in vivo calcium imaging and intracranial EEG for the first time, to reveal how microglia shape activity of complex neuronal networks in the healthy and the injured brain. Then, we will study microglia-neuron interactions from the network level to nanoscale level using in vivo two-photon imaging and super-resolution microscopy. We will apply novel chemogenic and optogenetic approaches to manipulate microglia in real time, assess their role in neuronal activity changes and investigate the molecular mechanisms in vitro and in vivo. Our unpublished data also suggest that inflammation \u2013 a key contributor to brain diseases \u2013 could disrupt microglia-neuron signaling and we set out to investigate the underlying mechanisms. By using state-of the-art research tools that had not been applied previously in this context, our studies are likely to reveal novel pathophysiological mechanisms relevant for common brain diseases.", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Hungary"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-04-01"], "Project_ID": ["724994"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITAETSMEDIZIN GOETTINGEN - GEORG-AUGUST-UNIVERSITAET GOETTINGEN - STIFTUNG OEFFENTLICHEN RECHTS", "UNIVERSITAETSMEDIZIN GOETTINGEN - GEORG-AUGUST-UNIVERSITAET GOETTINGEN - STIFTUNG OEFFENTLICHEN RECHTS"], "EU_Contribution": ["EUR 1 991 445"], "Project_Title": ["Computational Dissection of Effective Circuitry and Encoding in the Retina for Normal and Restored Vision"], "Total_Cost": ["EUR 1 991 445"], "Country": ["Germany", "Germany"], "Project_ACR": ["CODE4Vision"], "Technology_Description": "Understanding how neural circuits process and encode information is a fundamental goal in neuroscience. For the neural network of the retina, such knowledge is also of concrete importance for the development of vision restoration therapies for patients suffering from degeneration of photoreceptors. Artificial stimulation of retinal neurons through electronic implants or inserted light-sensitive proteins (\u201coptogenetics\u201d) aims at reconstructing natural transmission of visual information to the brain. Recreating natural retinal activity, however, will require a thorough understanding of the complex and diverse neural code of the retina. The challenge lies in deciphering the various nonlinear operations and dynamics in the around 30 parallel signalling streams that emerge from the retina, represented by as many types of ganglion cells, the retina\u2019s output neurons.", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["724822"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE"], "EU_Contribution": ["EUR 1 997 680"], "Project_Title": ["Single Molecule Nanoscale Sensors for Improved Therapies and Diagnostics"], "Total_Cost": ["EUR 1 997 680"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["NanoPD"], "Technology_Description": "One of the most significant challenges facing the healthcare community is the accurate and selective detection and quantification of trace levels of analyte. This can have enormous impact with numerous application, especially in the context of biosensing, where applications can range from early stage detection of disease to the identification of new markers amongst others. These challenges are compounded when the analysis of real samples or even complex mixtures are required. To address this need, single molecule or near single molecule methods are currently being heavily pursued which allows for the discrimination of events with low copy numbers by removing the \u201cclouding\u201d associated with ensemble averaging. Although strategies for detecting single molecules have existed for a number of years, efficient and cost-effective label-free methods without the need for chemical modification are lacking especially when considering smaller molecules directly in unprocessed clinical samples. As part of this proposal, I intend to address this limitation by developing new strategies in single molecule nanoscale sensing which will be both highly sensitive and selective for improved therapeutics and diagnostics applications.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["724300"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["ABERYSTWYTH UNIVERSITY", "ABERYSTWYTH UNIVERSITY"], "EU_Contribution": ["EUR 1 428 165"], "Project_Title": ["The Global as Artefact: Understanding the Patterns of Global Political History Through an Anthropology of Knowledge -- The Case of Agriculture in Four Global Systems from the Neolithic to the Present"], "Total_Cost": ["EUR 1 428 165"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["ARTEFACT"], "Technology_Description": "Knowledge is an anthropological constant that is indissociable from the birth and interactions of human societies, but is at best a secondary concern for scholars of international relations and globalization. Contemporary global studies are thus unable to account for the co-constitution of knowledge and politics at a macro-scale, and remain especially blind to the historical patterns of epistemic development that operate at the level of the species as a whole and have shaped its global political history in specific, path-dependent ways up to now.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["724451"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 149 989"], "Project_Title": ["Nano Impacts for Biomedical and Environmental Analysis"], "Total_Cost": ["EUR 149 989"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["NIBEA"], "Technology_Description": "NIBEA will turn the developments and understanding from NANOIMPACTS into real world analytical practice such that reliable analytical protocols are established, validated and demonstrated especially in the context of real world media (environmental, industrial, medical) providing an entirely new approach to nanoparticle analysis based on electrochemical measurements. ", "To": ["2018-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["727292"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["OSPEDALE SAN RAFFAELE SRL", "OSPEDALE SAN RAFFAELE SRL"], "EU_Contribution": ["EUR 1 496 994"], "Project_Title": ["Tracking and predicting neurodegeneration spreading across the brain connectome"], "Total_Cost": ["EUR 1 496 994"], "Country": ["Italy", "Italy"], "Project_ACR": ["NeuroTRACK"], "Technology_Description": "Current knowledge of neurodegenerative diseases is limited by poor understanding of how they progress through the central nervous system (CNS). It has recently been hypothesized that clinical progression in these conditions involves the systematic spreading of protein misfolding along neuronal pathways. Protein aggregates would trigger misfolding of adjacent homologue proteins in newly-affected regions, and this would propagate in a \u201cprion-like\u201d fashion across anatomical connections. This proposal seeks to decipher the mechanisms of network-based neurodegeneration by understanding how the complex architecture of brain networks (the connectome) shapes the evolving pathology of neurodegenerative diseases, and to develop tools for monitoring disease progression from presymptomatic to later stages of the disease. ", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Italy"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-04-01"], "Project_ID": ["714388"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE"], "EU_Contribution": ["EUR 1 975 829"], "Project_Title": ["Massive Gravity and Cosmology"], "Total_Cost": ["EUR 1 975 829"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["MassiveCosmo"], "Technology_Description": "The ambition of this research program is to challenge the nature of gravity, provide an alternative to dark energy, and pave the way towards a potential resolution of one the most tantalizing problems of physics today: The Old Cosmological Constant Problem.", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["724659"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITE DU LUXEMBOURG", "UNIVERSITE DU LUXEMBOURG"], "EU_Contribution": ["EUR 1 499 788"], "Project_Title": ["Electoral Legacies of War: Political Competition in Postwar Southeast Europe"], "Total_Cost": ["EUR 1 499 788"], "Country": ["Luxembourg", "Luxembourg"], "Project_ACR": ["ELWar"], "Technology_Description": "We know remarkably little about the impact of war on political competition in postwar societies in spite of the fact that postwar elections have garnered tremendous interest from researchers in a variety of fields. That interest, however, has been limited to establishing the relationship between electoral democratization and the incidence of conflict. Voters\u2019 and parties\u2019 electoral behaviour after the immediate post\u2010conflict period have remained largely neglected by researchers. The proposed project will fill this gap in our understanding of electoral legacies of war by analysing the evolution of political competition over the course of more than two decades in the six postwar states of Southeast Europe: Bosnia-Herzegovina, Croatia, Kosovo, Macedonia, Montenegro, and Serbia. Organised around three thematic areas/levels of analysis \u2013 voters, parties, communities \u2013 the project will lead to a series of important contributions. Through a combination of public opinion research, oral histories, and the innovative method of matching of individual census entries, the project will answer to which extent postwar elections are decided by voters\u2019 experiences and perceptions of the ended conflict, as opposed to their considerations of the parties\u2019 peacetime economic platforms and performance in office. In-depth study of party documents and platforms, party relations with the organisations of the postwar civil sector, as well as interviews with party officials and activists will shed light on the influence of war on electoral strategies, policy preferences, and recruitment methods of postwar political parties. And a combination of large-N research on the level of the region\u2019s municipalities and a set of paired comparisons of several communities in the different postwar communities in the region will help expose the mechanisms through which war becomes embedded into postwar political competition and thus continues to exert its influence even decades after the violence has ended.", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Luxembourg"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["714589"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["FUNDACIO INSTITUT DE CIENCIES FOTONIQUES", "FUNDACIO INSTITUT DE CIENCIES FOTONIQUES"], "EU_Contribution": ["EUR 1 829 288"], "Project_Title": ["How to build a brain? Engineering molecular systems for mechanosensation and -protection in neurons"], "Total_Cost": ["EUR 1 829 288"], "Country": ["Spain", "Spain"], "Project_ACR": ["MechanoSystems"], "Technology_Description": "Mechanical forces are ubiquitous signals that provide critical and dynamic information about the environments around cells and organisms. Signals about touch, sound, and movements are transmitted to specialized mechanoreceptors but also deform the neuronal cytoskeleton of the central nervous system, particularly when strong forces are involved. Although failures to sense and cope with stresses are linked to human diseases including peripheral neuropathies and dementias, little is known about the connections between biomechanics and disease. A major reason for this gap is the technical challenge of detecting forces and deformations within a living cell or organism. Given the poor prognosis associated with neurodegenerative diseases, spinal cord injury and neuropathies, there is a strong need to develop a better understanding of neuronal mechanics. ", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-05-01"], "Project_ID": ["715243"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 1 922 575"], "Project_Title": ["Surviving metabolism: acid handling and signalling"], "Total_Cost": ["EUR 1 922 575"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["Survive"], "Technology_Description": "Metabolism generates vast quantities of acid, which exerts broad-spectrum biological effects because protein protonation is a powerful post-translational modification. Regulation of intracellular pH (pHi) is therefore a homeostatic priority, but carefully orchestrated proton dynamics are a versatile signal.", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["723997"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 1 999 318"], "Project_Title": ["Large-Area Transparent Opto-Electronics using 2D Materials"], "Total_Cost": ["EUR 1 999 318"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["LATO"], "Technology_Description": "Research in 2D materials has increased dramatically since the first isolation of graphene in 2004, with diverse interdisciplinary studies. In the last few years, 2D material research expanded beyond graphene by the development of other 2D materials, such as monolayered transition metal dichalcogenides, black phosphorous, and Boron Nitride. There are hundreds of possible 2D crystals that can be isolated, with properties ranging from metallic, semi-metallic, semiconducting to insulating, depending on the material composition. Semiconducting 2D materials have attracting interest in next-generation electronics/opto-electronics such as transistors, photo-gated transistors, photo-detectors, solar cells, and light emitting devices (LEDs), molecular sensors and optical imaging sensors. The unique structural form of 2D materials provides several benefits over other existing materials: ultrathin, flexible, highly transparent, large surface to volume ratio, and 2D quantum confinement. High transparency LEDs are required for applications in transparent displays on glass panels. Many 2D based opto-electronic devices have used mechanical exfoliation from bulk crystals, but this is limited to small areas. Recent work on chemical vapour deposition (CVD) to grow wafer-scale 2D materials has opened up exciting opportunities for commercial exploitation and has accelerated the intensity of research in this field towards real applications. The vision of this proposal is to realize a new class of ultra-thin, flexible, large-area, transparent, high-sensitivity opto-electronic device arrays based on all 2D materials, with a focus on imaging sensors and LEDs. This will involve wafer-scale CVD synthesis of 2D materials including novel blue and green 2D semiconductors, optical spectroscopy to probe the interlayer interactions, atomic level structure-property correlations using advanced electron microscopy, and the nanoscale fabrication and testing of high efficiency devices.", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["725258"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 1 696 109"], "Project_Title": ["The Politics of Wealth Inequality and Mobility in the Twenty-First Century"], "Total_Cost": ["EUR 1 696 109"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["WEALTHPOL"], "Technology_Description": "Over the past decade scholars across the social sciences have grappled with the causes and consequences of economic inequality and social mobility. Income inequality has risen to levels unseen for a century. At the same time, economies in Europe and beyond have seen an even larger concentration in wealth, along with unprecedented volatility in asset markets such as housing and equities. These changes in the distribution of wealth have been of great economic and political consequence, with the debates over housing, inheritance, and capital taxation shaping contemporary political discourse. Yet, scholars of political economy remain beholden to analyses of inequality and mobility that examine only the flows of income in the labour market and ignore inequality and mobility in the stock of wealth held by citizens. WEALTHPOL is a ground-breaking interdisciplinary project with a series of three high-risk and novel work packages that transform our knowledge about wealth inequality and wealth mobility. WEALTHPOL 1 develops the first comprehensive collection of data about the distribution and inheritance of wealth in Europe and beyond. WEALTHPOL 2 provides the first political database of how governments shape the pattern of wealth through political pledges and policymaking, spanning seven decades and thirty-seven countries. Finally, WEALTHPOL 3 uses cutting-edge laboratory and survey experiments to expand our knowledge about what citizens think about wealth. WEALTHPOL draws these three strands together by connecting policy environments and the distribution of wealth to citizens\u2019 attitudes to wealth inequality and the kinds of policies that might shape it. In doing so, WEALTHPOL revolutionises our understanding of - and our capacity to respond to - the politics of capital in the twenty-first century in Europe and beyond.", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["724949"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 1 499 450"], "Project_Title": ["The Politics and Practice of Social Media in Conflict"], "Total_Cost": ["EUR 1 499 450"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["ConflictNET"], "Technology_Description": "Over the next five years an unprecedented number of initiatives will coalesce, contributing to an extension of the reach of the Internet to the world\u2019s most remote regions. While previous efforts to expand Internet access have focused on urban areas, current initiatives are leveraging new technologies from drones to satellites to provide affordable access to the worlds poorest, many of whom are in Africa and live in regions where the state is weak and there is protracted violent conflict. Current debates have largely focused on technical issues of improving access, or assumed ways that technology will help \u2018liberate\u2019 populations or improve governance. This project focuses on a key puzzle that is often overlooked: How does increased access to social media affect the balance between peace-building efforts and attempts perpetuate violence in conflict-affected communities? ", "To": ["2022-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["716686"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 1 199 319"], "Project_Title": ["Zooarchaeology and Mobility in the Western Mediterranean: husbandry production from the Late Bronze Age to Late Antiquity"], "Total_Cost": ["EUR 1 199 319"], "Country": ["Spain", "Spain", "United Kingdom"], "Project_ACR": ["ZooMWest"], "Technology_Description": "Human survival and success is substantially determined by the ability to move across the landscape and adapt. Consequently, \u2018mobility\u2019 is a crucial topic in historical and archaeological research. To overcome the seasonal scarcity of food and the related over-grazing of pastures, it is essential for animal husbandry to move across territories. However, the decision to allow or deny rights of way to mobile people and livestock depends on political judgements. How might these shape animal husbandry production, and society?", "To": ["2021-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["716298"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON", "UNIVERSITY COLLEGE LONDON", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 1 499 405,99"], "Project_Title": ["Can humans embody augmentative robotics technology?"], "Total_Cost": ["EUR 1 499 405,99"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom"], "Project_ACR": ["EmbodiedTech"], "Technology_Description": "Wearable technology is redefining the boundaries of our own body. Wearable robotic (WR) fingers and arms are robots, designed to free up or complement our hand actions, to enhance humans\u2019 abilities. While tremendous resources are being dedicated to the development of this groundbreaking technology, little notice is given to how the human brain might support it. The intuitive, though unfounded, view is that technology will fuse with our bodies, allowing our brains to seamlessly control it (i.e. embodied technology). This implies that our brain will share resources, originally devoted to controlling our body, to operate WRs. Here I will elucidate the conditions necessary for technological embodiment, using prosthetic limbs as a model. I will build upon knowledge gained from rehabilitation, experimental psychology and neuroscience to characterise and extend the boundaries of body representation towards successful adoption of WRs. I will combine behavioural, physiological and neuroimaging tools to address five key questions that are currently obscuring the vision of embodied technology: What conditions are necessary for a person to experience an artificial limb as part of their body? Would the resources recruited to control an artificial limb be shared, or rather conflict, with human body representation? Will the successful incorporation of WRs disorganise representations of the human limbs? Can new sensory experiences (touch) be intuitively inferred from WRs? Can the adult brain support the increased motor and cognitive demands associated with successful WRs usage? I will first focus on populations with congenital and acquired hand loss, who differ in brain resources due to plasticity, but experience similar daily-life challenges. I will then test body representation in able-bodied people while learning to use WR fingers and arm. Together, my research will provide the first foundation for guiding how to successfully incorporate technology into our body representation.", "To": ["2022-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-02-01"], "Project_ID": ["715022"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 1 999 892"], "Project_Title": ["Optical Manipulation of Colloidal Interfaces, Droplets and Crystallites"], "Total_Cost": ["EUR 1 999 892"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["OMCIDC"], "Technology_Description": "This multidisciplinary research programme is focussed on the optical manipulation of interfaces, droplets and crystallites in colloidal model systems. In particular, we will use holographic optical tweezing and confocal microscopy to study interfacial phenomena in three different phase separated colloid-polymer mixtures, exhibiting colloidal liquid-gas, crystal-gas and nematic-isotropic phase coexistence, respectively. First, we will determine the full potential energy landscape of the optical traps using the relation between interface fluctuations and deformed liquid-gas interfaces. This will then be used to study the complex and anisotropic interfacial properties of crystal-gas and nematic-isotropic interfaces. In addition, we envisage quantitatively investigating the nucleation of colloidal liquid droplets, crystallites and liquid crystalline droplets in optical traps positioned at well-defined heights above the interface, which is a direct and quantitative measure for the undersaturation. This allows us to systematically study the relation between the quench depth, nucleus size and nucleation times. We will furthermore nucleate multiple droplets, crystallites and liquid crystalline droplets to study their optical trapping controlled coalescence and detachment, which will shed completely new light on for instance the single particle structure and dynamics upon coalescence and detachment. Finally, we will introduce large probe particles into the phase separated colloid-polymer mixtures, which enables the study of important phenomena such as heterogeneous nucleation and capillary condensation, crystallisation and nematisation. This ambitious project opens up a huge range of exciting possibilities to gain a deep and fundamental understanding of interfacial phenomena in complex fluids by actively manipulating and controlling colloidal interfaces, droplets and crystallites.", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["724834"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 1 437 367"], "Project_Title": ["Power of Algorithms in Discrete Optimisation"], "Total_Cost": ["EUR 1 437 367"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["PowAlgDO"], "Technology_Description": "Convex relaxations, such as linear and semidefinite programming, constitute one of the most powerful techniques for designing efficient algorithms, and have been studied in theoretical computer science, operational research, and applied mathematics. We seek to establish the power convex relaxations through the lens of, and with the extensions of methods designed for, Constraint Satisfaction Problems (CSPs).", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["714532"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 212 194,80"], "Project_Title": ["Structural Dynamics of Membrane Receptors at native-like conditions"], "Total_Cost": ["EUR 212 194,80"], "Country": ["Denmark"], "Project_ACR": ["DYNAMO"], "Technology_Description": "Proteins embedded in cell membranes are vital signaling and trafficking platforms connecting the outside to the inside of a cell, and functioning as primary drug targets. DYNAMO is an integrative dynamic structural biology project, with the ambitious goal of developing and implementing comprehensive experimental and computational approaches for studying the structural dynamics of membrane receptors (MRs) and their complexes at native-like conditions. DYNAMO is highly interdisciplinary, combining protein chemistry and computational physics to study dynamical processes underlying the function of MRs, and is designed to combine the expertise of the fellow and host. The project will establish an integrated platform based on the nanodisc-technology and the combined use of low- and high-resolution structural biology techniques to bring unique and alternative insights into the structural dynamics of MRs containing \u201dfuzzy\u201d (i.e highly flexible) domains, and the role this plays in functional signaling assemblies. In order to broaden the scope of the project and secure a general applicability of the developed methodology, full-length tissue Factor (TF) and Ghrelin receptor (GHS-R1a) are selected as models of single-pass and multi-pass MRs. These MRs do not only display different topologies and functional assemblies but also different selectivity towards lipids. TF and GHS-R1a are central to blood coagulation and energy homeostasis, respectively, and also connected to genetic and metabolic disorders, and thereby not only relevant as model systems but also promising drug targets. The project will exploit the recent advances in SAXS/SANS- and NMR-based methods to study the TF and GHS-R1a in nanodiscs, with an emphasis on their conformational ensemble nature. Upon the establishment of the methodology, it will be extended to study the interaction with their endogenous ligands.", "To": ["2020-02-29, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["753487"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["Institut Catal\u00e0 de Recerca de l'Aigua, Fundaci\u00f3 Privada", "Institut Catal\u00e0 de Recerca de l'Aigua, Fundaci\u00f3 Privada"], "EU_Contribution": ["EUR 1 493 734"], "Project_Title": ["Three-dimensional nanoelectrochemical systems based on low-cost reduced graphene oxide: the next generation of water treatment systems"], "Total_Cost": ["EUR 1 493 734"], "Country": ["Spain", "Spain"], "Project_ACR": ["ELECTRON4WATER"], "Technology_Description": "The ever-increasing environmental input of toxic chemicals is rapidly deteriorating the health of our ecosystems and, above all, jeopardizing human health. Overcoming the challenge of water pollution requires novel water treatment technologies that are sustainable, robust and energy efficient. ELECTRON4WATER proposes a pioneering, chemical-free water purification technology: a three-dimensional (3D) nanoelectrochemical system equipped with low-cost reduced graphene oxide (RGO)-based electrodes. Existing research on graphene-based electrodes has been focused on supercapacitor applications and synthesis of defect-free, superconductive graphene. I will, on the contrary, use the defective structure of RGO to induce the production of reactive oxygen species and enhance electrocatalytic degradation of pollutants. I will investigate for the first time the electrolysis reactions at 3D electrochemically polarized RGO-coated material, which offers high catalytic activity and high surface area available for electrolysis. This breakthrough approach in electrochemical reactor design is expected to greatly enhance the current efficiency and achieve complete removal of persistent contaminants and pathogens from water without using any chemicals, just by applying the current. Also, high capacitance of RGO-based material can enable further energy savings and allow using intermittent energy sources such as photovoltaic panels. These features make 3D nanoelectrochemical systems particularly interesting for distributed, small-scale applications. This project will aim at: i) designing the optimum RGO-based material for specific treatment goals, ii) mechanistic understanding of (electro)catalysis and (electro)sorption of persistent pollutants at RGO and electrochemically polarized RGO, iii) understanding the role of inorganic and organic matrix and recognizing potential process limitations, and iv) developing tailored, adaptable solutions for the treatment of contaminated water.", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-05-01"], "Project_ID": ["714177"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 1 610 231"], "Project_Title": ["Atomic Scale Defects: Structure and Function"], "Total_Cost": ["EUR 1 610 231"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["AtoFun"], "Technology_Description": "Atomic scale defects play a key role in determining the behaviour of all crystalline materials, profoundly modifying mechanical, thermal and electrical properties. Many current technological applications make do with phenomenological descriptions of these effects; yet myriad intriguing questions about the fundamental link between defect structure and material function remain.", "To": ["2022-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-03-01"], "Project_ID": ["714697"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 1 499 429"], "Project_Title": ["Heart regeneration in the Mexican cavefish: The difference between healing and scarring"], "Total_Cost": ["EUR 1 499 429"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["CAVEHEART"], "Technology_Description": "Whereas the human heart cannot regenerate cardiac muscle after myocardial infarction, certain fish efficiently repair their hearts. Astyanax mexicanus, a close relative of the zebrafish, is a single fish species comprising cave-dwelling and surface river populations. Remarkably, while surface fish regenerate their heart after injury, cavefish cannot and form a permanent fibrotic scar, similar to the human heart. Using transcriptomics analysis and immunohistochemistry, we have identified key differences in the scarring and inflammatory response between the surface and cavefish heart after injury. These differences include extracellular matrix (ECM) proteins, growth factors and macrophage populations present in one, but not the other population, suggesting properties unique to the surface fish scar that promote heart regeneration. The objective of the proposed project is to characterise and utilise these findings to identify therapeutic targets to heal the human heart after myocardial infarction. First, we will analyse the identified differences in scarring and immune response between the fish in detail, before testing the role of the most interesting proteins and macrophage populations during regeneration using CRISPR mutagenesis and clodronate liposomes. Next, we will link the key scarring and inflammatory differences directly to both the genome and the ability for heart regeneration using new and prior Quantitative Trait Loci analyses. This will allow to find the most fundamental molecular mechanisms directing the wound healing process towards regeneration versus scarring. Together with an in vitro and in vivo small molecule screen directed specifically at influencing scarring towards a more \u2018fish-like\u2019 regenerative phenotype in the cavefish and mouse heart after injury, this will provide targets for therapeutic strategies to maximise the endogenous regenerative potential of the mammalian heart, with the aim to find a cure for myocardial infarction.", "To": ["2022-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-03-01"], "Project_ID": ["715895"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD"], "EU_Contribution": ["EUR 1 997 959"], "Project_Title": ["Galois theory of periods and applications."], "Total_Cost": ["EUR 1 997 959"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["GALOP"], "Technology_Description": "A period is a complex number defined by the integral of an algebraic differential form over a region defined by polynomial inequalities. Examples include: algebraic numbers, elliptic integrals, and Feynman integrals in high-energy physics. Many problems in mathematics can be cast as a statement involving periods. A deep idea, based on Grothendieck's philosophy of motives, is that there should be a Galois theory of periods, generalising classical Galois theory for algebraic numbers. This reposes on inaccessible conjectures in transcendence theory, but these can be circumvented in many important cases using an elementary notion of motivic periods. This allows one to set up a working Galois theory of periods in many situations of arithmetic and physical interest.", "To": ["2022-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-03-01"], "Project_ID": ["724638"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 212 194,80"], "Project_Title": ["The Importance of Barriers to Bird Migration"], "Total_Cost": ["EUR 212 194,80"], "Country": ["Denmark"], "Project_ACR": ["BIRDBARRIER"], "Technology_Description": "Understanding animal migration is one of the most compelling and challenging problems of modern biology. For a long time, we have been hindered by the large geographical scale of migratory movements and the small sizes of most migratory animals. Crossing barriers is a fundamental aspect of animal migration. Long-distance migratory birds face crossings of formidable barriers such as the Sahara Desert, Himalaya Mountains, or the Pacific Ocean twice a year, but even short-distance migrants travel across inhospitable habitats. Successful migration, and specifically successful barrier crossings, depend on the availability of favourable weather conditions aloft and suitable habitat during stopovers. Surprisingly little is known about the behaviours that guide billions of avian migrants to a successful barrier crossing. Advances in tracking technology and remote sensing now offer us new tools to track small migratory animals with extraordinary precision. I will use these new methods to study how nocturnally migrating songbirds manage barriers during their migration. With this action I aim to increase the understanding of (1) the behavioural strategies that birds use to negotiate large geographic features and (2) how barriers limit bird migration. The research will be conducted under PI Prof. Kasper Thorup in the Bird Migration Lab, Center for Macroecology, Evolution and Climate, at the University of Copenhagen. Prof. Thorup\u2019s group has advanced the front of global scale tracking of avian migration for the last decade, and possess the necessary expertise in spatiotemporal patterns. Further, I will spend a secondment at the Institute of Avian Research, Germany, and gain from Dr. Heiko Schmaljohann expertise in stopover behaviour. By combining my existing expertise in radiotelemetry tracking and migratory behaviour, with new skills in additional tracking techniques and analytic tools, this action will advance the research field and enhance my career as independent researcher.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["751692"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF YORK"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Ovine origins and diversity in north-eastern Europe"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["OVinE"], "Technology_Description": "Sheep (Ovis aries) is one of the most important and widely distributed domestic species worldwide according to the Food and Agriculture Organization of the United Nations (FAO), and considered one of the \u2018big five\u2019 livestock species alongside cattle, goat, pig and chicken. The high number of sheep breeds with worldwide distribution, and the 11,000 years alongside humans makes them a fascinating, yet difficult species to study. Important information on the history of domestic sheep has been obtained from ancient faunal remains using \u2018traditional\u2019 zooarchaeological methods based on osteology and morphology, with relatively less little contribution from ancient genetics, compared to domesticates such as dogs or horses. OVinE will train the early researcher Eve Rannam\u00e4e in state-of-the art methods from zooarchaeology and ancient genomics to document the introduction, spread, and development of domestic sheep. Focusing on north-eastern (NE) Europe, where studies on sheep history and diversity are scarce compared to the rest of Europe, but where the extant indigenous breeds are highly valued for their genetic diversity, OVinE will: 1) clarify the timing and origins of the first sheep in NE Europe; 2) decipher the development and improvement of sheep populations from the Late Neolithic (c. 3000\u20131800 BC) through to the Modern period (AD 1800\u20131950); 3) clarify the affinities between ancient sheep populations and local indigenous breeds.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["749226"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["STICHTING KATHOLIEKE UNIVERSITEIT"], "EU_Contribution": ["EUR 162 864,60"], "Project_Title": ["Structure-function analysis of the calcium channel TRPV5"], "Total_Cost": ["EUR 162 864,60"], "Country": ["Netherlands"], "Project_ACR": ["CRYO-EM TRPV5"], "Technology_Description": "Ion channels are proteins composed of a hydrophillic pore that facilitate ion flow across a plasma membrane. This ionic permeability is controlled by a set of essential properties affecting the channel activation and inactivation in response to voltage, ligands, or intracellular second messengers. The focus of the present project proposal, the transient receptor potential vanilloid channel (TRPV5), forms a specific category within the large TRP familiy of ion channels as it comprises a unique high selectivity for calcium ions together with a calcium-dependent inactivation mechanism that is incompletely understood. Detailed analysis of the TRPV5 channel will provide new structural insights into channel gating that can be extrapolated to other TRP channels, as the current knowledge on the TRP protein structure and its impact on the regulation of the channel function is still limited. ", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["748058"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF EDINBURGH"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Can histone code-like switches govern the multifunctionality of RNA-binding proteins?"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["MARS"], "Technology_Description": "Post-transcriptional control of human gene expression is conferred by >1000 mRNA-binding proteins (RNA-BPs), which determine the utilisation and fate of mRNAs, with the aetiology of a wide-range of disorders (e.g. neurological, inflammatory, and neoplastic) being due to their dysregulation. ", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["753803"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Road Diplomacy: International Infrastructure and Ethnography of Geopolitics in 21st Century Asia"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["Road Diplomacy"], "Technology_Description": "The objective of this project is to understand where, why, and to what extent roads are being built between China and South Asia and to untangle the inter-related geopolitical and social impacts of infrastructure development at village, national, and international scales. The project will first map road developments throughout the trans-Himalaya and second investigate the geopolitical drivers and social impacts of road construction. By combining innovative methods from geography, anthropology, and international relations, I will produce new empirical data on infrastructure development in 21st century Asia and illustrate the links between macro geopolitical processes and micro local experiences. Datasets will improve interdisciplinary communications for social scientists and between development practitioners, donor agencies, policymakers, and local stakeholders. The research is of relevance to EU citizens because understanding contemporary dynamics between rising powers like China and India provides context on 21st century global politics and will inform decision-making for EU investment and development interventions in Asia.", "To": ["2020-05-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-06-01"], "Project_ID": ["751131"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KATHOLIEKE UNIVERSITEIT LEUVEN"], "EU_Contribution": ["EUR 160 800"], "Project_Title": ["Investigating the interplay between VWF, platelets, and neutrophil extracellular traps inpathologies involving thrombosis of the microvasculature"], "Total_Cost": ["EUR 160 800"], "Country": ["Belgium"], "Project_ACR": ["VWF and NETs"], "Technology_Description": "Thrombosis is a complex process involving activation of endothelial cells, and their release of Weibel-Palade body contents such as von Willebrand factor (VWF) and P-selectin. This in turn recruits platelets which form aggregates, and leukocytes such as neutrophils. The recent discovery of neutrophil extracellular traps (NETs) described a novel antimicrobial function of neutrophils. NETs are extracellular chromatin strands containing microbicidal proteins. The release of histones, serine proteases, and myeloperoxidase concentrated on DNA fibers into the extracellular space can contribute to many pathologies. NETs can bind platelets and red blood cells and therefore also contribute to thrombosis. Activated platelets can in turn stimulate neutrophils to make NETs, creating a vicious thrombo-inflammatory cycle. ", "To": ["2019-10-02, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-03"], "Project_ID": ["747993"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Theranostic molecular zipper based switchable nanomedicine for overcoming drug resistance"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["NinZA"], "Technology_Description": "This Fellowship will bring an outstanding researcher from Sweden to the UK to gain new scientific and career skills to position him to become a leading independent academic in the interface of chemistry and biology for translational Nanomedicine. The fellow will design a new class of biomimetic zipper nano-architecture, combining an MRI-enabled SPION scaffold with a zip-unzip, temperature and pH-responsive multi-arm polymer to defuse drug resistant cell functions. These approach could greatly benefit the current investigation of new and alternate therapeutic procedures to overcome drug resistance. The fellow will gain advanced training in translational designs of drugs for recognition and treatment of drug resistant system, and in state of the art techniques for studying such system.", "To": ["2019-04-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-15"], "Project_ID": ["706694"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["KATHOLIEKE UNIVERSITEIT LEUVEN"], "EU_Contribution": ["EUR 160 800"], "Project_Title": ["Conflicts in start-ups: coping with stress and conflicts to promote well-being and entrepreneurial success"], "Total_Cost": ["EUR 160 800"], "Country": ["Belgium"], "Project_ACR": ["Starflict"], "Technology_Description": "Start-ups are Europe\u2019s 2020 Priorities for strengthening economic growth. However, about 50% of new European businesses fail during their first five years, conflicts between founders and effects of work stress being two of the top reasons for failure. However, conflicts and stress in start-ups, as well as factors for their entrepreneurial success are under-studied. ", "To": ["2020-01-01, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-02"], "Project_ID": ["745947"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE GRENOBLE ALPES"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Multi-Terminal Josephson Junctions as a novel platform for high dimensional topological matter"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["TopoInMulTermJJ"], "Technology_Description": "The spectrum of Andreev bound states in N-terminal Josephson Junctions (MulTJJ) may be viewed as a pseudo-bandstructure of N-1 dimension Bloch electrons. As we recently showed this pseudo-bandstructure may have interesting topological properties. (i) Topological transitions between ground states with different fermion parity may occur in a 3-terminal JJ upon varying the superconducting phases. (ii) In 4- or more terminal JJs, the pseudo-bandstructure may display Weyl nodes, that entail a non-trivial 1st Chern number in a 2D plane in the space of SC phase differences and lead to a measureable quantized transconductance under DC-bias voltage. ", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["753906"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF EDINBURGH", "THE UNIVERSITY OF EDINBURGH"], "EU_Contribution": ["EUR 1 199 805"], "Project_Title": ["International Organisations and the Rise of a Global Metrological Field"], "Total_Cost": ["EUR 1 199 805"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["METRO"], "Technology_Description": "The production of global metrics by International Organisations has not only penetrated the transnational social and policy fields; it has also become an integral mode of the ways International Organisations interconnect. Through their collaborative practices of quantification and commensuration, International Organisations are both constituting new realities and being reconstituted themselves. Thus, the dominance of global measurement regimes has profound implications for the ways International Organisations interact, and for the environments these new interrelationships come to generate. ", "To": ["2021-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["715125"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["TRAPEZA TIS ELLADOS AE"], "EU_Contribution": ["EUR 152 653,20"], "Project_Title": ["The Role of Global and Sectoral Factors in Labour Share Fluctuations"], "Total_Cost": ["EUR 152 653,20"], "Country": ["Greece"], "Project_ACR": ["GaSLS"], "Technology_Description": "This project will investigate the distribution of national income between profits and wages as proxied by the labour share in national income. The focus will be to identify the empirical regularities of factor shares in developed and emerging countries and across industries. In 1957, Kaldor established an influential stylised fact for macroeconomic modelling: the stability of the labour share. This finding, which has implications for macroeconomic dynamics, the shape of the production function and inequality, led social scientists to become 'silent' and to neglect research on labour share for many decades. Standard neoclassical growth and business cycle models, following Kaldor\u2019s stylised fact, assume a one-to-one substitution between capital and labour. However, the recent observation of a declining labour share points to an incomplete understanding of macroeconomic dynamics and to potentially erroneous policy implications drawn from these models. This has renewed the interest of macroeconomists to unveil the sources driving this decline. The proposed study on the fluctuations of the labour share from a solid empirical standpoint will provide the broad social science academic community and the policymakers with a better understanding of the behaviour of the labour share. In particular, this project aims at (i) reconciling the existing literature on the sources of labour share decline by examining a large set of driving forces and their relationship to key macroeconomic variables; (ii) providing a descriptive analysis of labour share from a multi-sector and multi-country perspective; as well as, a decomposition of labour share into national and external factors. This project will thus strictly link academic literature and policymakers\u2019 interests with issues such as what should be the appropriate response of governments to the observed decline of the labour share and its implications for fiscal and monetary policy.", "To": ["2019-07-02, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-SE - Society and Enterprise panel"], "Coordinated_in": ["Greece"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-07-03"], "Project_ID": ["746100"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["SIEMENS HEALTHCARE GMBH"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Matched Sampling Approaches for Statistical Inference in Large-Scale Clinical Neuroimaging Studies"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["zelig"], "Technology_Description": "Noninvasive neuroimaging techniques have shown much promise over the last decade in the investigation, diagnosis and in determining treatment of neurological disorders. However, to improve their predictive power and better understand underlying causative disease factors it will be essential to extend our investigations to empiric studies of large populations and to develop appropriate statistical models and define statistical procedure for use in such observational studies. It is the main objective of this project therefore, to develop and extend the methods of Causal Inference for use on large unstructured neuroimaging datasets. Specifically, this proposal seeks to 1) Develop and apply existing techniques from matched sampling to observational studies of imaging for Causal Inference. 2) Investigate the benefits of the same matched sampling procedures in support of classification models. 3) Industrial considerations: This is an enterprise panel proposal and will aim to integrate the developed technology into the Clinical Imaging Big-Data program at Siemens HealthCare (SHC), Erlangen. These objectives will be achieved by implementing and testing different Matched Sampling procedures using large observational neuroimaging datasets and assessing their performance through reduction in the specific forms of bias known to be present in observational data. These methods will be extended for use in classification models and the effects of matching on common prediction methods will be examined. The project is highly relevant for the work program as it will provide an opportunity to enhance training through Siemens and has the potential to facilitate a career move from academia to the non academic sector.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-SE - Society and Enterprise panel"], "Coordinated_in": ["Germany"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-06-01"], "Project_ID": ["752652"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Titanium Oxide Nanocomposites for Scalable Optimized Perovskite Solar cells"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["TONSOPS"], "Technology_Description": "The European commission recognizes the importance of nanotechnology, semiconductors and advanced materials as key enabling technologies. The application of functional nanostructured materials in industrial processes and advanced science is of capital and strategic importance for the European economy and society. Their inclusion as reliable, standard and affordable components will boost the competitiveness of European industry, specifically in the fabrication of 4th generation solar cells. Sensitized Perovskites Solar cells (PSC) represent advantages in terms of cost manufacturing, energy generation and integration in flexible and semitransparent devices. However, the viability of their mass scale fabrication is hindered by economic and technical difficulties. Some of these technical issues arise from inefficient infiltration of the perovskite absorber into a fragile mesoporous (mp) TiO2 layer. My project addresses these problems applying a recently developed straightforward method for secure TiO2 nanotube layers (TNL) to commodity thermoplastic polymers. This novel method combined with optimized solution synthesized perovskites will result in the production of flexible and pliable PSC. Specifically, I propose to produce a step change in the standardization and fabrication of functional nanostructured materials, and its implementation in optimized PSCs. Lastly, the study on the life cycle management and viability of the industrial production of these PSC will be evaluated in an innovative photovoltaic manufacture company, ONYX SOLAR. Hence, the project is designed to generate disruptive, but easily scalable technology that may be rapidly adopted by European industry to boost its competitiveness in functional nanostructured composites and 4th generation solar cells.", "To": ["2018-03-15, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2016-03-16"], "Project_ID": ["706094"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["STICHTING VUMC", "STICHTING VU"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["Responding or not responding to training; prediction of balance rehabilitation outcome from structural and functional brain networks in Cerebral Palsy."], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["CP-RehOP"], "Technology_Description": "When an injury occurs to the developing brain, as in Cerebral Palsy (CP), these children typically experience sensorimotor disorders such as muscle weakness, abnormal muscle activity, and ataxia. Poor balance control is a primary deficit in CP, which has a large impact on a child\u2019s daily life, since it is crucial for independent mobility and greatly affects the risk of falls. CP is the most common developmental cause of physical disability in the world, with a prevalence of 2-3 in 1000 live births. To improve their quality of life, adequate treatment is essential. However, studies investigating the effectiveness of balance rehabilitation in CP have revealed mixed results. This is due to two reasons. First, due to the various clinical scales and experimental measures available, each measuring different components of balance, it is very complex to diagnose balance control in CP. Second, it is currently unknown which are the underlying neural causes of poor balance control in CP.", "To": ["2018-02-28, Grant Agreement terminated |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["660458"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI ROMA TRE", "ISTANBUL TEKNOKENT ANONIM SIRKETI", "UNIVERSITEIT UTRECHT", "DISTRETTO AGROALIMENTARE REGIONALE SCRL", "VILNIAUS GEDIMINO TECHNIKOS UNIVERSITETAS VIESOJI ISTAIGA", "REDINN SRL", "ACADEMY OF SCIENTIFIC RESEARCH AND TECHNOLOGY ASRT", "UNIVERSITE SIDI MOHAMMED BEN ABDELLAH"], "EU_Contribution": ["EUR 796 500"], "Project_Title": ["Cluster Development Med"], "Total_Cost": ["EUR 796 500"], "Country": ["Italy", "Turkey", "Netherlands", "Italy", "Lithuania", "Italy", "Egypt", "Morocco"], "Project_ACR": ["CLUSDEV MED"], "Technology_Description": "The proposal lies within priority research & innovation topics in EU-Mediterranean cooperation, as highlighted in several past projects and policies reccomendations, i.e. within the MOCO - Monitoring Committee for Euro-Mediterranean Cooperation in RTD. International Cluster Cooperation offers opportunities to scal up research and technological potential, enhance competitiveness, support the regional socio-economic development and reinforce the market placement of new, innovative products. These cooperation approaches often fail due to constraints on resources, capabilities, instruments and funding. On the other hand, over 2.000 Clusters only in the European Union covering all sectors and able to realize an intersectorial framework, as well as related clusters and networks in the southern Mediterranean countries, form a great potential for transnational clustering. ", "To": ["2019-05-31, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Other", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-06-01"], "Project_ID": ["645730"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["UNIVERSITY OF DURHAM"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Church Building as Industry in Early Medieval Western Europe"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["CHISEL"], "Technology_Description": "This project interrogates the early medieval \u2018construction industry\u2019 with a specific focus on the ecclesiastical workshops responsible for producing masonry buildings in the Early Middle Ages (8th-11th centuries). Using state-of-the-art analyses of selected religious buildings that survive as standing structures in Spain, Portugal and England, the overarching aims of the proposal are threefold. Firstly, to study the industry of construction of masonry churches through analysis of the building processes, technologies and the material and skills-based investment at selected churches. Secondly, to develop an understanding of the architecture as a product in its social and economic context, and to measure its contribution to the early medieval economy. Thirdly to establish a suitable methodology for the analysis of the construction industry at this time across Western Europe. The combination of traditional and novel methodologies, including architectural archaeology, history, geology, cost calculations, structural analysis and reverse engineering will facilitate a new assessment of Early Medieval church-building programmes, offering a unique opportunity to redefine the economy and history of the Middle Ages by taking into account this industry in the context of other industrial sectors, charting the period from a new perspective and transcending the boundaries of traditional research. As part of the research programme, the candidate will acquire complementary knowledge in the field (mainly relating to Anglo-Saxon architecture), will be trained in new techniques (OSL, laser scanning, GIS/informatics and LiDAR) and will interact with researchers in the host organisation who have mutually complementary research expertise. Results will be disseminated by via a monograph and papers published in high-impact journals, and communicated to public by means of different activities.", "To": ["2018-08-31, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["702350"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITAET INNSBRUCK", "UNIVERSITATEA DIN BUCURESTI", "Instituto de Educa\u00e7\u00e3o da Universidade de Lisboa", "DOLNOSLASKA SZKOLA WYZSZA", "EOTVOS LORAND TUDOMANYEGYETEM", "Masarykova univerzita"], "EU_Contribution": ["EUR 3 472 230,24"], "Project_Title": ["European Joint Doctorate in Teacher Education"], "Total_Cost": ["EUR 3 472 230,30"], "Country": ["Austria", "Romania", "Portugal", "Poland", "Hungary", "Czech Republic"], "Project_ACR": ["EDiTE-EJD"], "Technology_Description": "The EDiTE joint research programme is a response to the current challenges in the complex processes of transformation of education professionals' career development. Particularly in focus is the teaching profession as central to all education systems. In the research area it is essential that typical national or regional perspective found in TE programmes are extended to include transnational perspectives. A European perspective on the academic level can only be fostered through joint European research.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-EJD - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-EJD)"], "Funding_scheme": ["MSCA-ITN-EJD - European Joint Doctorates"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["676452"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["TECHNISCHE UNIVERSITEIT DELFT", "TECHNISCHE UNIVERSITEIT DELFT", "WAGENINGEN UNIVERSITY"], "EU_Contribution": ["EUR 1 499 183,75"], "Project_Title": ["Adaptive immunity in prokaryotes: how Bacteria do not forgive and do not forget their enemies"], "Total_Cost": ["EUR 1 499 183,75"], "Country": ["Netherlands", "Netherlands", "Netherlands"], "Project_ACR": ["REMEMBER"], "Technology_Description": "Microbes in natural ecosystems are under constant evolutionary pressure from viruses. To survive in this hostile environment microbes have evolved an adaptive immune system called CRISPR-Cas. The immune system is based on incorporation of invader DNA sequences in a memory locus (CRISPR), the formation of guide RNAs from this locus, and the degradation of invading target DNA using CRISPR RNA-guided protein complexes. Invaders escape immunity by making point mutations in the targeted region of their DNA, but hosts quickly restore immunity by integrating new memory sequences against the same invader in a process called priming. Recently, I have made the remarkable discovery that hosts mount a primed immune response even when facing heavily mutated invaders. This implies that the memory of the CRISPR-Cas system not only functions in the short term against relatively recent threats, but also remembers a range of revisiting old foes in the long term, providing a huge evolutionary benefit for the host in the arms race with their invaders.", "To": ["2020-05-31, ongoing project |"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-06-01"], "Project_ID": ["639707"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["HELMHOLTZ-ZENTRUM BERLIN FUR MATERIALIEN UND ENERGIE GMBH", "HELMHOLTZ-ZENTRUM BERLIN FUR MATERIALIEN UND ENERGIE GMBH"], "EU_Contribution": ["EUR 1 987 500"], "Project_Title": ["Multiscale modelling of stimuli-responsive nanoreactors"], "Total_Cost": ["EUR 1 987 500"], "Country": ["Germany", "Germany"], "Project_ACR": ["NANOREACTOR"], "Technology_Description": "The catalysis by metal nanoparticles is one of the fastest growing areas in nanoscience due to our society's exploding need for fuels, drugs, and environmental remediation. However, the optimal control of catalytic activity and selectivity remains one of the grand challenges in the 21st century.", "To": ["2020-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2015-08-01"], "Project_ID": ["646659"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["HELSINGIN YLIOPISTO", "ILMATIETEEN LAITOS"], "EU_Contribution": ["EUR 191 325,60"], "Project_Title": ["The Foreshock and its Role in Solar-Terrestrial relations"], "Total_Cost": ["EUR 191 325,60"], "Country": ["Finland", "Finland"], "Project_ACR": ["FRoST"], "Technology_Description": "There is a critical need for accurate space weather forecasting, due to the growing use of technologies vulnerable to space weather hazards. However, refining the current models requires a more detailed understanding of solar-terrestrial relations, especially during extreme events such as magnetic clouds (MCs) which drive the fiercest storms at Earth. To this end, FRoST will investigate a previously unexplored aspect of the interaction of MCs with the terrestrial environment: the role played by the foreshock, a turbulent region extending upstream of the Earth's bow shock. The objectives of FRoST are (1) to characterise the foreshock properties during MC events, (2) to investigate how these alter in turn the properties of the region at the interface between the solar wind and the magnetosphere, the magnetosheath, and (3) assess whether the influence of the foreshock can be significant and thus should be included in space weather models. To undertake this challenging task, we will take on an interdisciplinary approach, combining numerical simulations and spacecraft observations. ", "To": ["2019-03-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2017-03-15"], "Project_ID": ["704681"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE"], "EU_Contribution": ["EUR 187 419,60"], "Project_Title": ["Synthesis of Low Noise Microwaves Using Solitons Locked to an Ultra-Stable Cavity"], "Total_Cost": ["EUR 187 419,60"], "Country": ["Switzerland"], "Project_ACR": ["SOLISYNTH"], "Technology_Description": "This project (SOLISYNTH) aims to utilize the novel crystalline microresonator optical frequency comb to synthesize ultra-stable microwaves. The microresonator comb will operate in the state of temporal dissipative soliton and an ultra-stable Fabry-Perot cavity will be used as a reference for the comb to lock to. By using direct optical division with the comb, this work could offer a new approach to synthesize low-phase-noise microwaves in a compact form factor, which could have applications in Radar, timing and telecommunications to radio astronomy. In addition, this project seeks to generate mid-infrared soliton comb with octave spanning bandwidth through dispersion engineering and quantum cascade laser pumping. With its exceptionally high coherence, such frequency comb offers access to the molecular fingerprinting region where many chemical species show distinctive absorption features. Devices based on this research output can find tremendous applications in mining, agriculture and medical diagnosis.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["753749"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["TECHNISCHE UNIVERSITEIT DELFT"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["Understanding nitrogen metabolic interactions in mixed anammox-based microbial communities"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["MixAmox"], "Technology_Description": "Improving current biological wastewater treatment plants (WWTPs) towards more reliable and resource-efficient solutions is a priority of the EU (Water Framework Directive). Successful biological treatments rely on the concerted activity of different microorganisms and thus optimized microbial community engineering strategies are required to achieve this goal. Processes based on anammox bacteria hold promise to reduce the energy and resource expenditures of WWTPs. However, our current knowledge of the different microorganisms involved and the environmental factors regulating their interactions in anammox-based microbial communities remains limited. The MixAmox project aims at advancing our fundamental understanding of the metabolic interactions and their implications for process performance in these communities through a multidisciplinary approach based on theoretical and experimental methods combined with cutting-edge molecular techniques and stable isotopes. The obtained results are expected to foster the implementation of anammox systems. Moreover, the developed methodological framework will be directly applicable for the study of any natural or engineered complex microbial community. ", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["752992"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAT AUTONOMA DE BARCELONA"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Unfair transitions? A critical examination low-carbon energy pathways in the EU from a domestic energy vulnerability perspective"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["TRANSFAIR"], "Technology_Description": "Energy transitions towards sustainability are driven by the need to reduce the environmental impacts of energy consumption, namely those related to carbon emissions. However, it is feared that a large scale deployment of low-carbon solutions that disregards pre-existing socio-economic and material inequalities may result in transitions deepening disparities or creating new energy-related vulnerabilities. Such prospect is particularly worrying as tens of millions of EU households are currently experiencing energy poverty, i.e., they are unable to access socially- and materially-necessitated levels of domestic energy services. Against this background TRANSFAIR aims to identify, conceptualise and empirically substantiate the ways in which the EU\u2019s \u201ctransition to a low-carbon, secure and competitive economy\u201d may (or not) be reproducing and reinforcing current energy vulnerability trends in Member States. To this end the research will combine the political ecology and environmental justice frameworks with transitions theory and multi-level governance perspective, conduct a critical, integrative review of scientific and policy literature and carry out an empirically-based examination of two complementary case studies: renewable electricity cooperatives in Spain and advanced thermal retrofits of multi-family buildings in Hungary. ", "To": ["2020-01-01, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-02"], "Project_ID": ["752870"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Profiting from ECO-innovation: the RolE of BUSiness model"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ECO_REBUS"], "Technology_Description": "ECO_REBUS aims to get a closer understanding of the process through which firms adopt and operate public voluntary eco-innovation policies, a kind of policy that has become increasingly central in policy makers\u2019 agenda. To achieve this objective, the project assigns a specific role to the concept of business model, defined as the configuration of customer sensing, customer engagement, value delivery and monetization components, that captures causal links between value creation and value capture at the business level. Specifically, the project will integrate the literature on eco-innovation and the one on business model to address how and why business model can make eco-innovation a central part of the firm\u2019s value creation and appropriation. To do this, ECO_REBUS will investigate -by a cognitive and processual perspective- the phases through which public voluntary eco-innovation policies are adopted and operated by firms.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["753274"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE PARIS DIDEROT - PARIS 7"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Rule-algebraic Simple Rewriting"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["RaSiR"], "Technology_Description": "The basis for this project consists in a mathematical framework previously developed by the applicant that allows to describe graph rewriting systems algebraically, the so-called rule algebraic framework. In order to advance and valorise the concept, this project proposes to develop a general concept for rule-algebraic simple rewriting (RaSiR), both for conventional graph rewriting and for a novel form of simplicial rewriting. Secondly, RaSiR will serve as the basis for developing rule-algebraic variants of trace compression and observable-update algorithms for the rewriting system Kappa. The final aim of the project consists in developing and implementing the so-called observable-centric bootstrapping algorithm (OCBA) as a module for the simulation suite KaSim for the Kappa language. Kappa is predominantly used for simulating biochemical reaction systems, which typically display an extremely high combinatorial complexity. The algorithms and software modules developed in this project will provide in particular an alternative to pure stochastic simulation via the SSA algorithm as currently implemented in KaSim, in the form of the OCBA module. This module will admit the generation of approximate observable distributions from individual pure states of the system by calculating algebraically truncations of the formal solution of the chemical master equation as well as the induced observable update functions. The project shall be hosted by Dr. Jean Krivine of the PPS team at IRIF at the University Paris-Diderot in France. Dr. Krivine is one of the two main developers of the KaSim simulation suite, and moreover one of the world experts in the theoretical and practical development of the programming language Kappa. IRIF will provide an ideal environment for the applicant to develop new skills, to be part the very interdisciplinary research team PPS, and to communicate and valorise the project results to the greater biochemical and systems biological simulation community.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["753750"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 171 349,20"], "Project_Title": ["Chimeric Antigen Receptor to generate Alloantigen-specific Regulatory T cells and promote allograft tolerance"], "Total_Cost": ["EUR 171 349,20"], "Country": ["France"], "Project_ACR": ["CAR ART"], "Technology_Description": "Organ transplantation is the best life-supporting treatment for terminal organ failure. Graft survival is however limited by rejection, a destructive process resulting from the response of recipient\u2019s immune system against donor specific alloantigens. Prevention of rejection currently relies on immunosuppressive drugs that lack antigen specificity and therefore increase the risk for infections and cancers. Induction of donor-specific tolerance would provide indefinite graft survival without morbidity and therefore represents the Grail of transplant immunologists. ", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2017-11-01"], "Project_ID": ["752869"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Origins of theory of mind: action prediction by great apes and human infants"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["MENTALIZINGORIGINS"], "Technology_Description": "Theory of mind (ToM) is the ability to impute unobservable mental states, such as desires and beliefs, to others. Our inferences about what others are thinking allow us to deceive and to empathize, to cooperate and to teach. For four decades, researchers have been attempting to elucidate the evolutionary and ontogenetic origins of this critical cognitive ability. In conflict with a long-held consensus, some have begun to argue that human infants (and to some extent great apes) share with human adults even the most cognitively sophisticated representational ToM abilities. To help resolve the intense resulting debate, this proposal presents a series of targeted experiments to test for several understudied but key ToM skills in great apes and human infants. The skills in question\u2014attribution of (a) unfamiliar desires, (b) ignorance, and (c) false perceptions\u2014form the basis of an organism\u2019s ability to distinguish others\u2019 minds from its own and build sequentially in terms of their cognitive and representational underpinnings. The present proposal marshals innovative new anticipatory looking eye-tracking methods and the most auspicious conditions available worldwide, through support of esteemed comparative and developmental psychologists Profs Josep Call and Malinda Carpenter and the School of Psychology and Neuroscience at the University of St Andrews, to address these major gaps in the social cognitive literature. The proposal\u2019s novel anticipatory looking methods, which assess participants\u2019 predictions based on their looks in anticipation of agents\u2019 acting on specific locations or objects, combine low task demands (like VoE paradigms) with clearer interpretability (much like action-based tasks). The proposal thus offers powerful tests of the hypotheses that great apes and human infants share with human adults a representational theory of mind. These studies will contribute key data to our understanding of the ontogenetic and evolutionary precursors of the human mind.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["752373"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITEIT ANTWERPEN"], "EU_Contribution": ["EUR 160 800"], "Project_Title": ["Novel electrochemical strategies for rapid, on-site multiscreening of illicit drugs"], "Total_Cost": ["EUR 160 800"], "Country": ["Belgium"], "Project_ACR": ["NARCOREADER"], "Technology_Description": "Drug use continues to be a problem of major concern for public authorities worldwide. According to the World Drug Report elaborated by the United Nations Office of Drugs and Crime (UNODC) approximately 207,000 drug-related deaths occur per year. With between 162 million and 324 million people aged 15-64 having used an illicit drug \u2014 mainly substances belonging to canabinoids, opioids, cocaine or amphetamine-type stimulants group \u2014 at least once in the previous year, drug abuse continues to have devastating consequences on human health. ", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["753223"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF LEEDS"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["How does dopamine link QMP with reproductive repression to mediate colony harmony and productivity in the honeybee?"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["DRiveR"], "Technology_Description": "Insects pollinate 80% of crop plants in Europe and pollination services contribute \u20ac22 billion to the European economy annually. The honeybee (Apis mellifera) is the most extensively managed pollinator species, yet populations are declining. Understanding the biology of the honeybee and and factors contributing to its decline is critical for food security and maintenance of biodiversity. ", "To": ["2020-02-29, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["752656"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["INSTITUT CURIE"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["A biophysical model for ESCRT-III mediated membrane scission"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["ESCRT model"], "Technology_Description": "My project focuses on the characterization of the mechanism of action of ESCRT-III complex. ESCRTs are evolutionary conserved proteins which mediate membrane remodeling and scission in a variety of important cellular processes, and are implicated in the pathogenesis of many diseases, including virus release and nuclear membrane repair during cancer cell migration. Despite intense research, many outstanding questions still remain unanswered, and all model proposed remain highly speculative. Based on our preliminary data, we propose a novel, unifying model for ESCRT-III function. The aim of the project is to provide solid data to support this model by an in vitro reconstitution approach, which would constitute a major contribution in the field. ", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2017-04-01"], "Project_ID": ["751715"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE BABRAHAM INSTITUTE"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["DNA Methylation dynamics during Gastrulation"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["MeGa"], "Technology_Description": "A fundamental aspect of biology is the understanding of how cell fates are established and maintained. Although it is widely accepted that epigenetic reprogramming is a central process of mammalian development, one of the most intriguing questions that remains unanswered is how DNA methylation marks contribute to cell differentiation and lineage commitment. By combining, novel single cell genomics techniques, CRISPR/dCas9 technology and innovative analytical approaches, this project will uncover the links between DNA methylation, gene expression and cell fate decisions during mouse gastrulation. This information will be used in a novel way to identify methylation signatures responsible for the stable repression of pluripotency, which has great potential to advance the development of safe iPS cells. Furthermore, this proposal will implement two innovative approaches utilising single cell DNA methylation patterns to reconstruct lineage trajectories of individual cells. This project capitalises on the unique combination of my novel analytical approaches, my background in DNA methylation analysis and evolutionary biology together with the extensive expertise in single cell techniques and developmental biology of the host lab. This multidisciplinary proposal will provide critical insights into how information is encoded in the epigenome and what this information can tell us about a cell\u2019s history within a developing organism. These results will significantly advance the field of epigenetics, developmental and stem cell biology. Finally, the knowledge and skills gained from this project combined with my scientific and personal development will hopefully open up exciting career possibilities with the long-term goal to establish my own research group in Europe.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations"], "From": ["2018-09-01"], "Project_ID": ["751439"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Mechanisms of sarcomeric protein homeostasis during physical exercise and ageing"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["REBUILD"], "Technology_Description": "During ageing muscle fibers are constantly subjected to high forces resulting in mechanical stress on cells and proteins. As a consequence they can degenerate, leading to suboptimal force generation, lack of coordinated movements and ultimately to muscle failure in the elderly population. This ageing process that leads to a progressive loss of muscle function has a major health impact on the ageing Western society. Physical activity is known to delay this decline.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2017-04-01"], "Project_ID": ["751236"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["AARHUS UNIVERSITET"], "EU_Contribution": ["EUR 200 194,80"], "Project_Title": ["A cross-country comparison of Communications designed to Prevent Radicalisation"], "Total_Cost": ["EUR 200 194,80"], "Country": ["Denmark"], "Project_ACR": ["CPR"], "Technology_Description": "The CPR project (A cross-country comparison of Communications designed to Prevent Radicalisation) analyses communications in the UK and Denmark that are designed to contribute to the prevention of vulnerable individuals being radicalised by terrorist groups such as ISIL. CPR will make a significant contribution to a problem facing many European states \u2013 namely how to effectively utilise strategic communications to counter terrorist propaganda. It is widely recognised in the literature that, to date, Western states have not been sufficiently effective in their counter-radicalisation communication strategies. It is unclear what a more prioritised communicative approach will mean in practice and communication efforts lack coordination between and, often, within countries to date. By employing an interdisciplinary theoretical approach and utilising unique access to new primary data in both states, CPR will, across four specific research strands, make three major contributions: i) generate a deeper and more nuanced empirical and conceptual understanding of the effectiveness of current counter-terrorism communications targeted at a range of audiences, ii) provide an empirically unique analysis of the challenges to effective prevention communications and, iii) provide empirically substantiated and theoretically informed communications-focused policy requirements that will improve the ability of practitioners and policy-makers to design and deliver communications that contribute to the prevention of radicalisation. CPR will employ a mixed methods methodology, incorporating semi-structured interviews for qualitative analysis alongside online surveys experiments to identify key quantative insights derived from new primary data. The project multi-actor and multi-level analysis in CPR moves beyond the state of the art in terms of methods and theory, access to data, and addressing new and broader questions in an under explored, and empirically lacking, area of research.", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["750348"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["INSTITUT CURIE"], "EU_Contribution": ["EUR 264 668,40"], "Project_Title": ["Discovery and validation of \u2018epidrivers\u2019 of cancer evolution and resistance to therapy"], "Total_Cost": ["EUR 264 668,40"], "Country": ["France"], "Project_ACR": ["METCLL"], "Technology_Description": "Intra-tumoral heterogeneity allows all form of cancers to undergo an evolutionary process in response to selective pressures, such as therapy, which results in a more aggressive disease. As chronic lymphocytic leukemia (CLL) are particularly amenable to evolutionary investigations, it has been shown that CLL\u2019s capacity to escape therapy is linked in to genetic evolution, which is fueled by intra-tumoral heterogeneity. Aberrant DNA methylation can also dysregulates genes involved in CLL pathogenesis. Like genetic alterations, DNA methylation modifications are heritable and subject to natural selection. Landau et al have studied sub-population DNA methylation heterogeneity in CLL and uncovered a large amount of stochastic variation. The acquisition of stochastic DNA methylation alterations enhances epigenetic plasticity and creates a non\u2013genetically encoded source of heterogeneity, fuelling tumour cells in their search for superior evolutionary trajectories. These new data modify the way we understand cancer epigenetics, and offer a new field of investigation: identify \u201cepidrivers\u201d, i.e. somatic epigenetic alterations leading to cancer-heterogeneity and which are positively selected through cancer evolution. ", "To": ["2021-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2018-09-01"], "Project_ID": ["750345"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSIDAD DE NAVARRA"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Locked between formulas: creativity in oral and transitional poetic texts"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["ORFORCREA"], "Technology_Description": "The human mind is capable of creativity and innovation unparalleled by any other species. At the same time, human beings elaborate and preserve complex and highly-stable traditions, transmitting them over very long time spans by means of the spoken word and through a variety of technologies, such as writing. How does human cognition give rise to such complex manifestations as oral poetic performance, and how are they affected by the introduction of writing? ORFORCREA investigates the cognitive basis of creativity in verbal art, examining its interplay with both oral tradition and literacy.", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["749952"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["BASF SE"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Functional Low-Intensity Light Upconverting Inks for Everyday Applications"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["FLUID"], "Technology_Description": "Spectral downconversion of visible or UV-light, that is the transformation of high-energy light into lower energy radiation, is used for a broad range of commercial products or applications and is therefore part of everyday life of most people. For example, highlighter pen inks contain organic dyes able to transform ambient UV-light into visible radiation making surfaces such as paper or fabric look bright. In contrast, optical effects based on light upconversion, that is the transformation of low-energy light into higher energy radiation, have barely been investigated since solid-state materials efficiently upconverting light at low intensities (< 100mW\u00b7cm-2) are only slowly emerging.", "To": ["2020-02-14, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-SE - Society and Enterprise panel"], "Coordinated_in": ["Germany"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-02-15"], "Project_ID": ["752143"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF LEEDS"], "EU_Contribution": ["EUR 97 727,40"], "Project_Title": ["Realizing the political rights of persons with disabilities"], "Total_Cost": ["EUR 97 727,40"], "Country": ["United Kingdom"], "Project_ACR": ["PODI"], "Technology_Description": "Taking as its point of departure the adoption of the UN Convention on the rights of persons with disabilities the fellowship \u2013 Realizing the political rights of persons with disabilities (PODI) \u2013 examines under which conditions disabled people\u2019s organisations are most likely to achieve voice and influence on decision-making processes of importance for their own lives and for society as a whole. The United Nations Convention on the Rights of Persons with Disabilities requires state parties, and the EU, to \u2018closely consult with and actively involve persons with disabilities\u2019, notably \u2018through their representative organizations\u2019. Enhancement of opportunities for disabled people\u2019s organisations to fully participate in policy process will assist the EU in furthering its wider ambitions to engage civil society, and to fulfil its international treaty obligations to the UN on disability rights. The fellowship \u2013will produce new knowledge to help make this a reality. It will launch the first cross-national and multilevel study of disability movements in Europe, beginning with in-depth data from four European countries (Germany, Italy, Norway and UK), and from EU and UN institutions. PODI will collect and analyse data on individual and organisational level as well as at national, EU and international level. PODI will identify implementation facilitators and barriers and make proposals for indicators to aid the EU and the Member States in monitoring their fulfilment of the UNCRPD (Articles 4.3, 29 & 33). A European centre of excellence (the Centre for Disability Studies at the University of Leeds, UK) will collaborate with an experienced researcher (Dr Rune Halvorsen, Norway) and civil society organisations of persons with disabilities (via the European Disability Forum) for intersectoral knowledge transfer, career development, and European added value.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["749519"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF LINCOLN"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Global Ecological Custodianship: Innovative International Environmental Law for theAnthropocene"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["GLEC-LAW"], "Technology_Description": "International environmental law (IEL), with multilateral environmental agreements (MEAs) as its main component, has not been able to address the underlying causes that are responsible for the socio-ecological crisis of the Anthropocene and it seems unable to respond to this crisis. By providing the fellow with a sustained opportunity to interrogate IEL\u2019s principal MEAs in the context of the Anthropocene, this project seeks to investigate a) the normative implications of the Anthropocene for law and IEL specifically; b) explain why and to what extent MEAs have contributed, and have been unable to respond to, the Anthropocene\u2019s socio-ecological crisis; and c) to propose a global ecological custodial framework of care (GLEC-Law) to reform these MEAs. Lawyers have been unable to present a comprehensive solution to MEAs' deficiencies and failures, while Anthropocene scientists have been unable to meaningfully translate their insights into the juridical domain. Responding to this knowledge gap, this multi-disciplinary project brings together an experienced researcher and an internationally recognized research group with global expertise to problematize the failures, deficiencies and potential of MEAs in the Anthropocene and to propose reforms of these MEAs. The fellow brings expertise on environmental law, governance and constitutionalism to the host and secondment institutions, including access to global and global South networks, while contributing to establishing the host as a leading multi-disciplinary European center of excellence in law, governance and Anthropocene studies. The fellow will gain methodological and doctrinal training in IEL and Anthropocene related sciences. The project\u2019s scientific importance, operationalised through its 3 work packages and associated scholarly impact and dissemination activities, lies in its original contribution as the first multi-disciplinary study to view MEAs through the lens of the Anthropocene and its associated constructs.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["751782"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["EIDGENOESSISCHE FORSCHUNGSANSTALT WSL"], "EU_Contribution": ["EUR 187 419,60"], "Project_Title": ["The Role of extreme drought and legacy EFfects of long-term manipulatiOn of water availability on growth and REproduction of ScoTs pine REFOREST"], "Total_Cost": ["EUR 187 419,60"], "Country": ["Switzerland"], "Project_ACR": ["REFOREST"], "Technology_Description": "Drought has been identified as an important driving factor for forest decline, hence the long-term tree-level growth assessment in relation to drought events is necessary to understanding resistance and resilience of forests. In addition, the seedling physiological responses (photosynthesis and respiration) to varying growing conditions are key to forecast the future composition of temperate forests in Europe. Younger stages of a tree\u2019s life cycle are more sensitive to climate variations than the adult stage. Recent studies demonstrate the important role of transgenerational epigenetic effects for the adaptive capacity of a tree. Although the epigenetic control of gene expression during drought has been shown in trees at the molecular level, little is known at the physiological level. In this context, the overall objectives of this study are to quantify radial growth of Scots pine and oak along a latitudinal gradient from southern France to northern Germany with particular focus on the effects of extreme events, and to quantify the potential role of epigenetic effects on seed germination, seedling establishment and survival in variable growing conditions (temperature, light and water). The objective-1 will be based on annually resolved tree-ring data covering the entire gradient. The distinct role of epigenetic changes on seedling growth and survival (objective-2) will be accomplished applying transplanting experiments with seed from long-term irrigated trees (13 years) and trees growing under natural dry conditions, in the field and in the laboratories of WSL, Switzerland. The project will explore the adaptive strategies used by Scots pine trees to drought events, which will strengthen our understanding on the complex relations among climate and ecophysiological mechanisms, essentially benefiting the development of sustainable forest management strategies under climate change in Europe.", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Research Organisations"], "From": ["2017-11-01"], "Project_ID": ["749051"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE QUEEN'S UNIVERSITY OF BELFAST"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Predictive modelling of GPCR druggable allosteric sites"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["MIDAS"], "Technology_Description": "G protein coupled-receptors (GPCRs) are the most successful class of druggable targets in the human genome with an estimated 30 to 60 % of prescription drugs in European Union. GPCRs biological state can be modulated by small molecule ligands acting on spatially distinct allosteric binding sites (ABSs) that result more selective and less toxic than drugs binding to orthosteric sites. The discovery of lead compounds targeting ABSs is challenging and to date has largely been achieved through cost-intensive and time-consuming high-throughput screening. The recent release of X-ray structures of GPCRs in the complex with allosteric modulators opens new opportunities to develop structure-based computer aided methodologies to identify ABSs.", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["748830"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE"], "EU_Contribution": ["EUR 175 419,60"], "Project_Title": ["An elastocapillary-enabled self-tunable microfluidic chip"], "Total_Cost": ["EUR 175 419,60"], "Country": ["Switzerland"], "Project_ACR": ["El_CapiTun"], "Technology_Description": "I am a French citizen with international training in Soft Matter, a growing field that combines Physics, Chemistry and Mechanics. My publications include high-impact factors journals and attract media attention. I am applying to MSCA fellowships to work with Prof. Gallaire and his group at EPFL, Lausanne, Switzerland.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["750802"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE"], "EU_Contribution": ["EUR 175 419,60"], "Project_Title": ["Heat Transport and its Effects on the Performance of Nanostructured, Photonic Materials"], "Total_Cost": ["EUR 175 419,60"], "Country": ["Switzerland"], "Project_ACR": ["PhotoHeatEffect"], "Technology_Description": "The PhotoHeatEffect project aims to create a breakthrough in our understanding and ability to control heat transport and exciton-phonon coupling in nanophotonic structures. Both phenomena generate detrimental effects like local heating and charge carrier escape in current generations of light emitters. Bridging phononics and photonics will reveal the physics behind such device limitations, hence allowing to develop countermeasures leading to better phononic and photonic designs. Tailoring the heat flow and the coupling between the phonon bath and excitons in nanophotonic structures has strong potential for numerous applications with a wide scope comprising life sciences, optogenetics, electronics, and data transmission. The project will not only boost the European competitiveness in the fields of thermal transport and phononics, both still dominated by US scientists, but even strives to pioneer a unique linkage to photonics. By employing nitride materials - a key research asset in the EU and at the host institute - it will be possible to encompass a wide range of emitters that already affect our everyday life (Nobel Prize in Physics 2014). Such polar nitrides are an ideal choice as they are relevant for classical (light-emitting diodes) and non-classical light sources (few-photon emitters, nano-, and polariton-lasers), which are both suffering from the phononic properties dictated by the material system. The project will resolve this relation by manipulating the phononic dispersion relation and the excitonic dipole moment independently by a phononic crystal comprising by design tunable electric fields. An analysis of these manipulations will be achieved by combining two-laser Raman thermometry and \u00b5-photoluminescence spectroscopy. While the latter technique and an analysis of the exciton-phonon coupling match the expertise at hand, the progression towards thermometry and phononics will boost the applicant\u2019s track record supported by a unique network of partners.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["749565"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Hybrid Entanglement of Light for Interconnected Optical Networks"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["HELIOS"], "Technology_Description": "In quantum information science and technology, two main encodings of information are traditionally used: a \u2018discrete-variable\u2019 (DV) approach, based for instance on single photons, and a \u2018continuous-variable\u2019 (CV) one, which relies on continuous degrees of freedom such as amplitude and phase of a light field. A mostly unexplored area combines these two different approaches to create \u2018optical hybrid schemes\u2019. Recently, entanglement between particle-like and wave-like optical qubits, i.e. CV-DV entanglement, has been generated for the first time by the host group. This resource holds the promise of heterogeneous quantum networks where the two encodings can be combined or interconverted. In this context, the proposed research activities aim at investigating, harnessing, and using the potential of this yet unexplored photonic resource.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["749213"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["The Constitutional Place of Expertise"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["CONPLEX"], "Technology_Description": "The project explores how constitutional principles can enhance the democratic legitimacy of expert-based decision-making in the European Union (EU). It does so by focusing on participation, transparency and administrative rationality, as interpreted by European Courts when reviewing expert-based decisions, and as incorporated into institutional practices involving both scientific and economic expertise. In particular, CONPLEX aims at detecting links and influences between Courts\u2019 activity and decision-making processes, capable of leading to a deeper integration of expertise within the constitutional discourse. The proposal draws on a new legal realist approach to legal research, and combines doctrinal analysis of the Courts\u2019 case-law and empirical investigation of institutional practices \u2013 through documentary analysis and semi-structured interviews to Commission\u2019s officials and experts. The project is original from a conceptual, methodological and empirical perspective and makes a timely contribution to the on-going debate on technocracy and democracy in the EU, especially with regard to the role played by scientific and economic experts in politically controversial issues.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["748463"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE PAUL SABATIER TOULOUSE III"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Exploring LIfestyle Transitions: a molecular and physical anthropology approach of ancient Yakut people"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["ELITE"], "Technology_Description": "Adaptation, whereby organisms become fitted to their environment, is a key evolutionary process driving biodiversity. Our understanding of how natural selection impacts genetic diversity has greatly advanced with recent developments in high-throughput DNA sequencing and genome-wide selection scans. However, microbiomes and epigenomes are other systems selection can act upon as they influence our health and phenotype, and thus our fitness. Although microbiomes, epigenomes and genomes can now be reconstructed, no study has evaluated their relative importance in populations exposed to new selective pressures. This is what ELITE aims at achieving by reconstructing the history of the biological changes undergone by the Yakut people of Far Eastern Siberia after their contact with Russians in the 17th century, and the resulting profound lifestyle transition, diet shifts and massive epidemiological outbreaks. By applying a multidisciplinary approach combining the latest advances in physical anthropology, ancient genomics, metagenomics and epigenomics to a unique collection of cultural and biological material from ancient Yakuts, ELITE proposes an innovative experimental approach in evolutionary biology, which could eventually reveal a possible maladaptation to our modern lifestyle, making us more susceptible to diseases. The success of ELITE will be based on the excellent synergy between the experienced researcher and the host institution, as the applicant will benefit from state-of-the-art facilities and expertise to gain advanced training in physical anthropology methods, while applying her genomic skills to a sample set available at no other research institution in the world. By acquiring these new skills in an international context, the experienced researcher will become a fully trained evolutionary anthropo-genomicist at the interface of physical and molecular anthropology, which will place her in ideal conditions to develop as a mature and independent researcher.", "To": ["2019-09-03, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-04"], "Project_ID": ["748122"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["NATURAL HISTORY MUSEUM"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Systematic Characterisation and Archiving of megafauNa on a regional scale in a Deep-sea area threatened by mining"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SCAN-Deep"], "Technology_Description": "The worldwide demand for metals and rare-earth elements is increasing, fuelled by developing economies and the growth of high-technology green industries. The Clarion-Clipperton Zone (CCZ) in the tropical eastern Pacific Ocean contains vast reserves of polymetallic nodules on the abyssal seafloor, a future source of deep-sea minerals already targeted for exploitation. There is an almost complete absence of open biodiversity data on the large animals (megafauna) of this 6 million km2 area, and it is a pressing conservation priority to establish baseline data to enable future sustainable management of the region. In particular, a regional-level assessment that cuts across contracted areas is urgently needed to [1] establish the baseline quantitative ecology of the region, [2] assess species richness and ranges and thus, [3] enable the successful management of this globally important marine area in the context of a global \u2018blue growth\u2019 agenda. The objective of this fellowship is to develop the first regional-level approach to megafauna classification and identification in the CCZ. This will be done using a three-fold approach: (1) The development of a new open-access data-archiving bioinformatic pipeline for imagery and samples of megafauna from the entire CCZ, (2) the identification and characterization of megafaunal morphotypes observed across the CCZ regardless of exploration contract area and (3), development of biodiversity survey methods based on organismal DNA found in the environment (metabarcoding). This project will include knowledge transfers between the host and experienced researcher in the following areas: bioinformatics, digitisation, image analysis, megafauna taxonomy, DNA barcoding, metagenomics and transferable skills such as project management, scientific communication including science-policy interface work, laboratory health and safety, and career planning.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2017-09-01"], "Project_ID": ["747946"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["EOTVOS LORAND TUDOMANYEGYETEM"], "EU_Contribution": ["EUR 134 239,20"], "Project_Title": ["Extremal Sparse Graphs and Graph Limits"], "Total_Cost": ["EUR 134 239,20"], "Country": ["Hungary"], "Project_ACR": ["ExtSpGraphLim"], "Technology_Description": "This proposal focuses on two related families of problems concerning algebraic invariants of graphs, i.e., networks. On the one hand, we study extremal values of algebraic invariants, i. e., we propose to give lower and upper bounds for certain algebraic graph parameters in a given class of graphs like d{regular graphs. On the other hand, we study the behavior of algebraic invariants of very large graphs, more precisely we study whether for a certain graph parameter p(G) it is true that the sequence (p(G_n)) converges if the graph sequence (G_n) converges in some sense. The two families of problems are connected by the observation that many graph parameter does not achieve its extremal value on finite graphs, but on some infinite object which is the limit of finite graphs.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Hungary"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["747430"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FUNDACION PARA LA INVESTIGACION MEDICA APLICADA FIMA"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Advancing cancer immunotherapy using natural killer cells for hematological and metastatic cancers"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["CINK"], "Technology_Description": "The development of monoclonal antibodies (mAb) to target tumor cells has tremendously improve cancer immunotherapy and benefit the treatment of aggressive cancer such as some types of lymphomas, leukemias, multiple myeloma and metastatic cancers. One of the mechanisms of action is the induction of antibody-dependent cellular cytotoxicty (ADCC) through the activation of CD16 on NK cells after binding to the Fc portion of Ab-coated tumor cells. Therefore, strategies that combine NK cell activation and mAb therapy has been intensively explored. However, tumor heterogeneity and unstable expression of the targeted molecule in the tumor cells limits ADCC for mAb therapy resulting in cancer relapse. Furthermore, intrinsic NK immunregulatory mechanisms as well as NK-specific tumor evasion mechanisms have also negatively impacted the use of NK cell-based therapies. In this proposal we will explore the mechanisms involved in the reduced NK cell function (NCF) observed after ADCC and/or NK cell activation (NCA) in order to develop novel strategies to achieve a sustained and stronger NCF by combining stimulating signals with suppression of inhibitory signals such as costimulation via CD137 and IL12, or SHP1/2 blockade. We hypothesize that the adoptive transfer (AT) of NK cells expanded by this novel method will result in better anti-tumor responses after mAb therapy even in tumor cells that express limited amount of the target molecule and limiting consequently cancer relapse rates. Furthermore, due to the overall improvement on NCF, we expect that the combination of AT NK cells with hematopoietic stem cell transplantation (HSCT) will also increase anti-tumor responses; which efficacy up to date has shown to be rather limited. Given the versatility of our approach, this therapy can be used for the treatment of many cancers, but particularly hematological and metastatic cancers and potentially can be translated into the clinic in a short time frame.", "To": ["2020-02-14, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2018-02-15"], "Project_ID": ["746985"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITEIT LEIDEN"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["Deep Investigation on Molecular Processes At early Cosmic Times"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["DeepIMPACT"], "Technology_Description": "The discovery of galaxies formed when the Universe was less than 1 Gyr old has been a major breakthrough of extragalactic astronomy. During this period, called Epoch of Reionization (EoR), the Universe experienced a dramatic change: from being a dark \u201csea\u201d of neutral hydrogen and helium, it got completely reionized and polluted with elements heavier than helium. Thus, characterizing the bulk of galaxy population at these early epochs is pivotal because of their strong impact on the cosmic evolution.", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["746119"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FUNDACION UNIVERSITARIA SAN PABLO-CEU"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["An Integrated Computational and Experimental Approach to Rapid Synthesis of Highly Selective Dual-Targeted HDAC/CK2, MMP2/CK2 Inhibitors"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["DUALITY"], "Technology_Description": "Traditional drug design strategy based on a single target has serious difficulties in developing new therapies for diseases such as cancer.", "To": ["2020-02-29, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["746225"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6"], "EU_Contribution": ["EUR 264 668,40"], "Project_Title": ["CArbon Production of under-ICE phytoplankton blooms in a changing Arctic Ocean"], "Total_Cost": ["EUR 264 668,40"], "Country": ["France"], "Project_ACR": ["CAP-ICE"], "Technology_Description": "Over the last decades, sea-ice in the Arctic Ocean (AO) has undergone unprecedented changes, with drastic decline in its extent, thickness and duration. Modern climate models are unable to simulate these changes, leading to large uncertainties in Arctic and Global Change predictions. Sea-ice strongly attenuates solar radiation and it is generally thought that phytoplankton, which drives Arctic marine CO2 sequestration, only grow in open waters once sea-ice retreats in spring. However, the discovery of large under-ice phytoplankton blooms (UIBs) growing beneath sea-ice contradicts this paradigm. UIB productivity in ice-covered regions has been suggested to be ten-fold larger than presently modeled. By initiating an international network (USA, France, Canada, Germany, Norway), the CAP-ICE project will acquire knowledge on the occurrence of UIBs, the physical mechanisms that control their initiation and productivity, and will quantify how UIBs affect the Arctic carbon cycle and climate.", "To": ["2021-01-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-15"], "Project_ID": ["746748"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE"], "EU_Contribution": ["EUR 175 419,60"], "Project_Title": ["High Performance Wide Bandgap and Stable Perovskite-on-Silicon Tandem Solar Cells"], "Total_Cost": ["EUR 175 419,60"], "Country": ["Switzerland"], "Project_ACR": ["POSITS"], "Technology_Description": "The world is moving toward a low-carbon future. The EU Commission\u2019s 2015 Paris climate agreement vowed to keep global average temperature to well below 2\u00b0C above pre-industrial levels and undertake rapid global emission reductions. Generation of clean energy such as photovoltaics is one of the most promising solutions. Novel organic-inorganic perovskite materials for solar cells have drawn vigorous scientific interest over the past few years due to their potential low cost, high charge carrier mobility, absorption coefficient and efficiency. The two top scientific journals, Nature and Science, selected perovskites as one of the biggest scientific breakthroughs in 2013. As perovskites are still in the early development stages, barriers need to be overcome before they can be commercialized. This interdisciplinary project draws from chemistry, physics and engineering with the aim of developing stable high bandgap mixed-cation/halide perovskite devices. Both photo- and moisture stability will be carefully studied and improved upon leading to the ultimate goal of fabricating a stable monolithic perovskite/silicon tandem solar cell with an efficiency >30%. Monolithic perovskite/silicon tandem technology has the potential to revolutionize the photovoltaics industry by greatly decreasing cost through improved efficiency making clean energy more competitive against fossil fuels. The project will be conducted at EPFL PV-Lab, a dedicated photovoltaic research centre with over 30 years of experience and close links with Swiss and European research institutes and industries. EPFL is a highly-ranked European engineering institution with world-class facilities, industrial connections and technological parks. The fellow Dr. Terry Chien-Jen Yang will be joining PV-Lab to bring unique nano-material and analytical expertise as well as collaborations from the prestigious School of Photovoltaic and Renewable Energy Engineering, UNSW in Sydney, Australia.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["747221"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ARCELIK A.S."], "EU_Contribution": ["EUR 145 845,60"], "Project_Title": ["Development of nano-Photocatalytic Materials for Indoor Air Purification and Odour Elimination"], "Total_Cost": ["EUR 145 845,60"], "Country": ["Turkey"], "Project_ACR": ["nanoPhotoMat"], "Technology_Description": "Pollutants released directly to the air are particularly harmful compared to soil and water pollutants. These pollutants severely affect people\u2019s life quality and life expectancy. Indoor air purification at highly populated urban areas is technically challenging, because indoor air contaminants arise from both outside and indoor sources. The most hazardous indoor pollutants are volatile organic components, toxic inorganics, dust, bacteria, pollen and mold spores. Conventional ventilation brings outdoor air pollution inside the buildings and thus increases energy consumed for cleaning per room. Adapting new technological advances will help meeting requirements of a compact, reliable, and eco-friendly design. The main objective of this proposal is therefore to develop the next generation air purifiers where photocatalytic oxidation (PCO) technologies will allow elimination of a variety of hazardous indoor air pollutants, and bad odour caused by such pollutants, when illuminated by low-power light sources on-the-fly. The proposed project composes of four different phases: the state-of-the-art design of photocatalysts, selection of proper illuminating source, configuration of PCO system, and preparation of the first prototype. In this study, we will address the limited work performed within the field hitherto, such as the mechanism of catalyst deactivation, efficiencies of odour removal, generation of by-products, electron-hole recombination phenomenon, and the ways of providing anti-bacterial/good hygiene properties. We will carry out an in-depth investigation on optimization of PCO air purification system within an interdisciplinary work at Ar\u00e7elik Central R&D. After designing a viable configuration, we will focus on the production of a PCO air purifier prototype. In accordance with Ar\u00e7elik Group\u2019s policy and vision, our final goal is to ready the highly energy-efficient, low-noise, and reliable PCO air purifier prototype for the product launch in the global market.", "To": ["2019-06-04, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-SE - Society and Enterprise panel"], "Coordinated_in": ["Turkey"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-06-05"], "Project_ID": ["746094"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE"], "EU_Contribution": ["EUR 187 419,60"], "Project_Title": ["Deformable vascular registration for co-mapping altered hemodynamics with vascular responses,and for introducing a new measure for aneurysm rupture risk assessment: the local surfacegrowth"], "Total_Cost": ["EUR 187 419,60"], "Country": ["Switzerland"], "Project_ACR": ["VASCFORM"], "Technology_Description": "Growth rate of ascending aortic aneurysm (AsAA) is a rupture risk marker as it potentially reflects a wall remodeling that leads to fast growth. It is measured as the maximum diameter change over time. However, expansion is not uniform but presents localized growth. We propose to develop a methodology based on deformable surface registration tools that will provide correspondence between aortic surface meshes obtained at consecutive time points and quantify vascular surface growth distribution. The direct application of this methodology in animal and clinical research will answer some long debated questions about AsAA pathology. While a cause and effect relationship between hemodynamics and lesion development is long suspected, exact quantification of the responsible hemodynamic factors has not been performed so far. This is because the geometry changes between baseline (measurement of initiating hemodynamics with computational fluid mechanics) and end stage (lesion development), making it difficult to identify corresponding regions at the microscopic level of lesion size. We will use angiotensin II-infused ApoE-/- mice, a model for AsAA, and apply the developed registration methodology to obtain a detailed correspondence between the 3D images, and co-map the complex initiating hemodynamic microenvironment and the histological findings at sacrifice for the identification of disturbed hemodynamics. Furthermore, the local wall expansion can indirectly provide information about aneurysm state. We will associate maximum local growth with the degree of aneurysm initiation (size of media tear) which will be used as a groundwork and pre-clinical justification to introduce the regional growth measurement in clinical risk assessment. Lastly, clinical data from AsAA patients will be used in order to correlate the maximum regional growth with clinical outcome, which will establish a new metric for a more sensitive aneurysm growth quantification.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["747094"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE DE STRASBOURG"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Antiferromagnetic spin-chiral triangles as decoherence-free qubits"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["CHIRALQUBIT"], "Technology_Description": "Quantum Information Processing (QIP) is a groundbreaking new field with implications ranging from overcoming Moore's law to the security of encrypted communications. As such it has been identified as a priority by the European Commission. With several theoretical concepts having been clearly defined, and with quantum limits to Moore's law approaching, it is now important to find materials that will allow the physical implementations of qubits, the principal components for QIP. Molecular Nanomagnets (MNMs) are promising such materials which, however, exhibit short quantum decoherence times. CHIRALQUBIT identifies a new quantum property of MNMs, spin chirality, as a means to overcome this limitation and achieve decoherence-free qubits, with the added advantage of their rapid and precise electric manipulation. The project\u2019s objectives are to confirm for the first time the electric control of spin-chiral coordination complexes, in particular antiferromagnetic triangles of half-integer spins, and study their relaxation and decoherence dynamics regarding transitions reversing their spin chiralities.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["746060"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE QUEEN'S UNIVERSITY OF BELFAST"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Protecting Human Rights and Public Health in Global Pandemics: A Map of the Standards Applied by EU and US Courts"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["THEMIS"], "Technology_Description": "THEMIS asks: How do judges resolve the conflict between individual human rights and public health caused by global pandemics such as Zika, Ebola and SARS? Building on the researcher\u2019s expertise in both EU law and risk regulation, and the supervisor\u2019s pioneering \u2018risk within rights\u2019 framework, it focuses on EU and US case-law to create the first comparative map of judicial standards in this challenging field. It develops the role of law in pandemic preparedness; a crucial issue affecting all of us, and meets the aims of the 3rd EU Health Programme. In so doing, THEMIS recognises that lawyers do not act alone, and that the scholarly and the practical have a reciprocal impact. Thus it utilizes a \u2018Lawyers meet Doctors\u2019 dissemination strategy, facilitating inter-disciplinary impact on academic and policy experts. It features two inter-sectoral secondments enabling access to both key EU and global policy-makers (WHO; the Public Health Agency in NI), and cross-disciplinary knowledge-transfer and networking via international workshops co-run with the host institution\u2019s Centre of Excellence for Public Health (one of five in the UK). The researcher\u2019s home at Queen\u2019s will be the Health & Human Rights Unit, the first such unit within a top 20 UK law school. Queen\u2019s also enjoys \u2018HR Excellence in Research Status\u2019 and boasts a Gender Initiative for women staff and a long-established Human Rights Centre. Each of these supports the skills and training plan, as do the project\u2019s varied outputs: including a monograph (essential for the researcher\u2019s independent academic position), journal articles, and presentations to both the lay public and policy experts during the secondments. In line with IF objectives, THEMIS enables the researcher to use international mobility, new networks and training to attain a position of leadership in the scholarly community, and contributes to the need for a better understanding of how to prepare for, and respond to, the risks of global pandemics.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["746014"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["INSTITUT CURIE"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["A quorum sensing mechanism regulating CD4 T cell proliferation"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["CD4CRISPR"], "Technology_Description": "The fine and complex regulation of CD4 immune response is important in cancer, autoimmune diseases, inflammatory disorders and viral infection. If signals orchestrating productive CD4 T-cell responses are well documented, the contraction of antigen (Ag)-specific CD4 T-cell populations following the resolution of primary immune response is however not molecularly understood. It has been demonstrated that a negative feedback loop can regulate CD4 T cell proliferation through direct T-T interactions, leading to the preferential exclusion of Ag-experienced T cells. This T cell intrinsic mechanism limits the expansion of effector CD4 T cells and may then interfere with therapeutic vaccine efficacy. Using Cas9-(constitutive/inducible)-expressing Dby-reactive T cells (from a TCR Transgenic RAG-/- mouse strain named Marilyn) coupled to a sgRNA library and an in vivo selection strategy, we will extensively identify the negative regulators of CD4 T cells migration and priming in an ongoing primary immune response. As a proof of concept, we will first inactivate candidate genes (already known to be involved in CD4 T cells negative regulation: TGF-b receptor,IFN-\u03b3 receptor, PD-1 and PD-L1) in Ag-experienced memory CD4 T cells, which will be enriched for their proliferative capacity in vivo and used as a second cohort in immunized mice. Then, we will develop a genome-wide screen approach to generate a library of knockout Ag-experienced T cells as a second cohort. We expect that further insight into CD4 suppressive mechanisms, which dampen efficient antitumor immune responses, will allow optimization of cancer immunotherapy.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2017-04-01"], "Project_ID": ["743435"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ELVESYS SAS"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Multi-compartmental Organ-on-a-Chip"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["MOOAC"], "Technology_Description": "Drug development is stuck in an innovation gap, in which it incurs staggering expenses and takes many, ten to fifteen, years to get a drug to market, furthermore, during the process many animals are sacrificed in preclinical work, and in the end many times the results from the animal studies does not accurately predict what will happen in humans, resulting in failures, delays, and recalled drugs. There is currently a gap in the preclinical testing platform for therapeutics. Organ-on-a-chip technologies of closing this gap, and have the potential of curtailing the high experimental costs and complexities associated with in vivo studies, and eventually evolving into next generation tools for therapeutic validation and development. ", "To": ["2020-03-15, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-SE - Society and Enterprise panel"], "Coordinated_in": ["France"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-03-16"], "Project_ID": ["753743"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["TECHNISCHE UNIVERSITAET MUENCHEN"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Robotic self/other distinction for interaction under uncertainty"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["SELFCEPTION"], "Technology_Description": "There will be around 35 million private or non-industrial use robots in the world by 2018, a market of 19 billion euros. However, autonomous robot technology in Europe is not yet ready to lead this high expectancy due to the lack of robust functionality in uncertain environments. Particularly, safe interaction is an essential requirement. A basic skill, still unachieved, is to allow the robot to be aware of its own body and perceive other agents. Recent evidence suggests that self/other distinction will be a major breakthrough for improving interaction and might be the connection between low-level sensorimotor abilities and conceptual interpretation.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["741941"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Phosphate homeostasis and energy metabolism in Dictyostelium discoideum"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["PHEMDD"], "Technology_Description": "Adenosine triphosphate (ATP) is the universal biological energy currency. Its cellular concentration is tightly regulated and depends on rates of glycolysis, oxidative phosphorylation, and obviously on phosphate availability. How is phosphate concentration regulated as a function of the cell\u2019s demands? Inositol pyrophosphates, described as metabolic messengers, are excellent candidates to orchestrate phosphate homeostasis and energy metabolism. The research programme proposed here aims to elucidate the relationships between phosphate homeostasis, energy metabolism, and inositol pyrophosphates using the amoeba Dictyostelium discoideum as a model system. This organism has high levels of inositol pyrophosphates and inorganic polyphosphate (polyP) and, surprisingly, a comparatively low level of ATP, suggesting that inositol pyrophosphates may serve as a phosphate reservoir for ATP production. I will use a combination of metabolomics analysis, steady-state and dynamic flux analysis of ATP, polyP, Pi and inositol pyrophosphate levels, and a functional analysis of mitochondria to evaluate the impact of polyP and inositol pyrophosphates on the metabolic/energetic state of this organism. I will investigate the function of polyP, which is induced during development, to understand how and why phosphate homeostasis is so dramatically modified during this process. This will be the first comprehensive analysis of the relationships between phosphate homeostasis and energy metabolism in eukaryotes.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["752903"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF WOLVERHAMPTON"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Epistemological Gaps in Cultural Theories of the Soviet East and Democratic West in the 1960s and 1970s"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["EGap"], "Technology_Description": "In this project the fellow is concerned with opening out the period of Brezhnev\u2019s Thaw in the Soviet Union in the 1960s and 1970s, to a renewed scrutiny. Covering art theory, cultural theory, philosophy, and political philosophy, the research will draw on both key and forgotten works, such as those by Evald Ilyenkov, Yuri Davidov, Lev Vigotsky, Georg Lukacs and Mikhail Lifshitz, as well as the critical legacy of Moscow conceptual art in order to better understand the dynamics of Soviet culture and its influence on contemporary culture, politics and art in Europe. This fellowship will challenge the largely negative perception of the cultural and philosophical achievements of this historical period. By using a cross-disciplinary approach, the fellow will demonstrate how the Brezhnev period, contrary to received views, produced a rich array of heterodox social theories, critical thinking, and cultural practices, that are comparable to Western emancipatory thinking and cultural theory of the time, but, remain, in quality, ambition and character, very different to their Western counterparts. The fellowship aims, then, to transform the conventional approach to post-socialist studies within the European academic context, in order to support and enhance a much needed cultural dialogue between the European Union and Russia.", "To": ["2019-11-06, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-11-07"], "Project_ID": ["752417"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ISTANBUL TEKNIK UNIVERSITESI"], "EU_Contribution": ["EUR 157 845,60"], "Project_Title": ["Developing Stretchable Conductive Fibres and their Implementations in Wearable Electronics"], "Total_Cost": ["EUR 157 845,60"], "Country": ["Turkey"], "Project_ACR": ["Wearonics"], "Technology_Description": "Europe needs to take action to develop stretchable conductive materials to lead to the wearable electronics industry, which will be worth over $30 billion dollars in 2020. Although flexible electronics are dominating the current wearonics industry, their applications are restricted due to significant reduction in their conductivity under the applied strain. All stretchable conductors with mechanical compliance materials like human skin are required for epidermal electronic devices and wearable electronics. The ideal solution to this problem would be using a stretchable conductive material that can be woven into washable and breathable fabrics, which remains a significant challenge. To address this challenge, I have formulated an innovative and interdisciplinary strategy based on my research experience to develop stretchable conductive fibres (SCF) using silver nanowires and spandex fibre. After developing SCFs, I will bring together diverse academic and industrial experts to utilize SCFs in 4 different research environments. First, I will receive intensive training at the Wireless Communication and Research Lab to utilize SCFs in wireless communication and pervasive computing systems. Then, I will integrate these systems into the disabled friendly apparels at Universal Textile Centre. Finally, I will be seconded to two industrial organisations, ComfTech and Antelope, to create SCF based prototypes of Health Monitoring Systems and Electro Muscle Stimulation technologies. This fellowship will allow me to gain new expertise in multiple disciplines, and build complementary international partnerships between academia and industry, which will enable me to enhance my independence as a researcher in the wearonics field. The successful completion of this timely and innovative project will result in an advanced material that will contribute to the competitiveness of Europe in the wearonics field.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Turkey"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["739891"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["LINNEUNIVERSITETET"], "EU_Contribution": ["EUR 173 857,20"], "Project_Title": ["Gender Aspects of Screen Adaptations of the British Nineteenth-Century Female Literary Canon"], "Total_Cost": ["EUR 173 857,20"], "Country": ["Sweden"], "Project_ACR": ["GASAC"], "Technology_Description": "The aim of the project is to analyse the gender aspects of British and American screen adaptations of selected nineteenth century women\u2019s novels. As the contemporary popular culture is increasingly reliant on adaptation and other derivative types of cultural texts such as sequels, retellings, and pastiche, it becomes vital to study the continued appeal of canonical literature. The project aims to study screen adaptations released between 1990 and 2010, which are internationally known and became parts of the shared collective cultural experience, influencing the popular perception of European nineteenth-century culture and the position of women within that culture. The project will consist of four components: (1) studying the adaptation authors\u2019 (directors, screen writers etc.) stated motivations and perceptions of the original writers, revealed in interviews, DVD commentaries and other ancillary materials; (2) analysing the nature of \u201cnovel to film\u201d changes, with special attention to the portrayal of female characters and the issues of women\u2019s agency and empowerment; (3) studying the role of the visual elements, e.g. costumes, scenography, cinematography and editing in the portrayal of female characters (4) analysing the receptions of adaptations and studying the possible \u201cfilm to novel\u201d transmission. The proposed research project is highly interdisciplinary in nature, aiming to use in a complementary way the perspectives of adaptation studies, gender studies and reception studies and film studies. It is based on solid theoretical founations (understanding he nature of the transmedial shift), but also involves a case-study approach to the chosen novel-and-adaptations clusters. Its expected impact is to offer a comprehensive analysis of the issues of women\u2019s agency and empowerment in the selected adaptations and to study the influence of these adaptations on the audiences' perception of the nineteenth-century culture.", "To": ["2019-10-01, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-02"], "Project_ID": ["750690"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KING'S COLLEGE LONDON"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Ebola virus manipulation of the cellular stress responses"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["StressEBOV"], "Technology_Description": "Ebola virus (EBOV) is a highly pathogenic filovirus that causes severe haemorraghic fever and killed over 11,000 people during the recent epidemic in Western Africa. Although potential vaccines and drugs are being tested, no treatment has been approved. Therefore, understanding the cellular regulation of EBOV replication is fundamental to develop novel treatments. ", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["750621"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Adapting to Change: Experimental Evolution of Environmental Sensing Systems in Bacteria"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ESSEVOL"], "Technology_Description": "Background: Coping with ever-changing conditions is a problem common to most living things. One solution that organisms have come up with is the evolution of systems that allow them to sense and respond to their surroundings. Despite being usually complex and costly to maintain, sensing devices are widespread throughout the Tree of Life, which has puzzled researchers for years. Theory has identified a number of scenarios that promote the emergence of environmental sensing systems. Yet, most aspects of their origin and evolution remain obscure; largely due to the practical difficulties of observing these processes in real time. Here I propose to fill this gap by combining experimental evolution with the Host Group's expertise on the molecular regulation of bacterial behaviour. Methodology: The plan is to couple sudden changes in growth conditions with arbitrary environmental cues (e.g., toxic metals) to select for bacteria capable of reading these cues and altering their behaviour accordingly. I will target a well-studied behaviour: motility, which plays a key role in nature allowing bacteria to find good conditions and move away from threats. Using this setting, I will test decades-long hypotheses about the genetic and ecological factors that shape the emergence of novel sensing systems. Later, I will exploit the power of new DNA sequencing techniques to work out how genetic changes drive the new behaviours. Impact: This research will shed light on how readily novel sensing systems can evolve, thus contributing to efforts to understand pressing issues such as the emergence of multi-drug resistance pathogens or the response of natural populations to the current global change. Outcomes could also help in the design of novel antimicrobial drugs and microbe-based reporters with applications in bioremediation (e.g., detection of contaminants), biotechnology (e.g. monitoring of industrial processes) and in Public Health (e.g., detection of pathogens in water supplies).", "To": ["2019-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["750129"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI TORINO"], "EU_Contribution": ["EUR 176 203,80"], "Project_Title": ["Patterns of diffusion and social implications of Massive Open Online Courses (MOOCs): A comparative study between United States and Europe"], "Total_Cost": ["EUR 176 203,80"], "Country": ["Italy"], "Project_ACR": ["MOOC_DaSI"], "Technology_Description": "The MOOC_DaSI project aims to develop a comparative study between the United States and Europe investigating patterns of diffusion of Massive Open Online Courses (MOOCs) and their contribution to a \u201csmart ad inclusive growth\u201d through: a) broadening access to education and b) providing individuals with better skills. MOOCs have been pointed out as a flexible, customized, cost-effective type of education that may play a key role in the future of higher education. However, the outburst of MOOCs also brought about contrasting arguments and so far empirical research is limited and fragmented. The project will contribute to shed light on this topic investigating two main research questions. The first deals with the organizational aspects of MOOCs diffusion and will explore whether a \u201cEuropean way\u201d to MOOCs can be identified. The second investigates whether MOOCs do contribute in reducing social inequality by a) broadening access to higher education to non-traditional and socio-economically disadvantaged students; b) providing returns on the labour market. Finally, the research project will summarize a series of policy recommendations providing policy-makers with empirical ground for designing effective policies in the context of open educational resources. MOOC_DaSI will adopt an interdisciplinary approach spanning between organizational studies, sociology of education and stratification research. The project will also make use of mixed methods of research, combining qualitative and quantitative data and different methods of analysis. The MOOC_DaSI project will be carried out at the University of Turin (IT) and Stanford University (USA) over a period of 24 months, including a secondment period at the EC-JRC in Seville (ES). The implementation of the project will contribute to enhance the fellow\u2019s expertise and thus the chances to reach her career objectives of establishing an own research group and obtaining future grants for large international projects.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["750242"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAETSMEDIZIN GOETTINGEN - GEORG-AUGUST-UNIVERSITAET GOETTINGEN - STIFTUNG OEFFENTLICHEN RECHTS"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["TIMING FERTILIY- A Comparative Analysis of Time Constructions and the Social Practice of Egg-Freezing in Germany and Israel"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["TIMEGG"], "Technology_Description": "\"Technological advancements in reproductive medicine have introduced the new concept of \"FREEZING\". Nowadays, healthy women are given the possibility to cryopreserve their oocytes in order to prolong their fertility, a procedure known as \"social egg freezing\". There is an ongoing bioethical academic and public debate on the social and ethical implications of this practice. The here proposed socio-empirical research is interested in extending our understanding of the concept of \"freezing\" in broader contexts, while analyzing it through the prism of 'sociology of time'. Egg freezing constitutes an extremely fascinating paradigm for studying concepts of time, timing, planning and its social-technological manipulation related to modern life science. In line with the IF work program's focus on creativity, innovation and diversity, this research aims to examine the interplay of culture and bioethics in an interdisciplinary and empirical manner, focusing on and comparing experts' and lay positions and using a cross-cultural German-Israeli comparative research framework. This cross-cultural comparison is especially interesting since the German regulatory and legal framework regarding new reproductive technologies is rather restrictive, while the Israeli regulation has been identified as extremely permissive. Using qualitative in depth interviews with relevant experts as well as users of social egg freeing, this research aims at (a) In-depth empirical analysis of time in the context of reproductive medicine; (b) A cross sectional analysis of social egg freezing by comparing two national contexts as well as experts and ordinary (lay) ethics; and (c) Theorization of the time dimension for the relationship of reproduction, labor and gender. Thus, this innovative research is expected to enhance the researcher academic competence and the transfer of new knowledge.\"", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["749889"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["Institut Catal\u00e0 de Recerca de l'Aigua, Fundaci\u00f3 Privada"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Groundwater quality assessment in areas with intensive livestock: is manure recycling a major source of pollution and dissemination of antibiotic resistance genes?\u201d"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["RESOURCE"], "Technology_Description": "Groundwater protection is one of the latest environmental battlegrounds in Europe. It is used as a major source for drinking water production all over Europe and as such, the preservation of its chemical and microbiological quality is of vital importance. In agricultural areas with intensive livestock activities, groundwater quality might be seriously compromised by the excessive use of manure as organic fertilizer. Animal manure may contain high levels of organic contaminants (e.g. antibiotics, nitrogen-containing compounds) and bacteria carrying antibiotic resistance genes (ARGs), and its reuse as soil amendment could be an important route of entry of these pollutants into groundwater bodies. This project aims at broadening the knowledge about the role of animal manure recycling as a major source of groundwater pollution by: (i) analyzing selected multiple-class antibiotics and ARGs and (ii) using an innovative approach, based on the bulk characterization of dissolved organic matter (DOM) by high resolution mass spectrometry (HRMS), to uncover the chemical pattern of selected manure-impacted groundwater bodies, used as sources for drinking water production, and provide evidence about the role of manure recycling as a major source of aquifer pollution. RESOURCE is a project with high societal relevance in Spain. The shutdown of large scale manure treatment plants in 2014 and the subsequent generation of large amounts of untreated waste might endanger the good chemical and microbiological status of drinking water wells. Thus, the outcomes of this project will be highly valuable to assess the current status of groundwater bodies and will contribute in preventing serious environmental and human health issues. The fellow\u2019s expertise, gathered in international top research institutions and the outstanding infrastructure and capabilities available at ICRA, makes an ideal conjunction for the successful completion of the project.", "To": ["2019-10-01, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-10-02"], "Project_ID": ["750104"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["INSTITUT BARCELONA D ESTUDIS INTERNACIONALS, FUNDACIO PRIVADA"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Electricity in the Mediterranean: Promoting good regulatory governance"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["RELMED"], "Technology_Description": "In the face of rising concerns for energy security and for climate change, huge investment projects about the production of renewable energies in the Southern Mediterranean area are under consideration. Regulatory reform and good governance of electricity markets, offering a stable and competition-based regulatory regime, are fundamental to inspire the trust of potential investors. However, their authoritarian political culture, political instability and developmental policies make Southern Mediterranean countries an unfavourable ground to the development of good regulatory governance. ", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["748135"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["Institut Catal\u00e0 de Recerca de l'Aigua, Fundaci\u00f3 Privada"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Development of a smart workflow based on high resolution mass spectrometry for the assessment of the performance of wastewater treatment technologies"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["SMART-WORKFLOW"], "Technology_Description": "Discharges from wastewater treatment plants (WWTPs) are one of the major sources of aquatic pollution. The increased detection of a wide range of organic micropollutants in the aquatic environment shows the limitations of conventional WWTPs (developed and designed to protect natural aquatic systems and water resources mainly by removing loads of carbon, nitrogen and phosphorous) in removing these compounds. Therefore, advances in WWTP technologies are crucial to limit the burden of WW-originated contaminants. To date, one of the main challenges is to appropriately evaluate the different treatment technologies regarding their potential to minimize the toxicological risks for biota and human health. The main objective of SMART-WORKFLOW is to integrate the last advances in high resolution mass spectrometry (HRMS) and statistical analysis of data to develop and optimize a smart methodology (workflow) for the assessment of the overall quality of wastewater treatment. Treatments that will be evaluated include the ones (i) based only on physical processes (e.g. membrane filtration or carbon adsorption) where there is no change in the chemical identity of the pollutants and (ii) with changes in the identity of the pollutants due to chemical reactions, including biological treatments or advanced treatments based on oxidation processes (AOPs). The generated workflow is understood as a procedural sequence for data acquisition, data processing and data mining and it will be applicable to both already-known and new wastewater treatments, providing a rapid assessment on its performance regarding the removal of polar organic compounds and generated transformation products (TPs). The present project aims to produce a substantial impact on the field of water research, one of the Europe\u2019s Societal Challenges.", "To": ["2020-03-15, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2018-03-16"], "Project_ID": ["747698"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITEIT LEIDEN"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["Advanced graphene nanodevices with functional hydrogels for DNA sequencing"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["GRAPHNANOGEL"], "Technology_Description": "With this proposal, I propose a new chemical approach inspired by DNA gel electrophoresis to slow down DNA translocation through a graphene nanopore or a nanogap, and to reduce the mechanical fluctuations of the graphene membrane as DNA translocates. Thus far using graphene nanodevices to sequence DNA molecules in real time has been hampered by two major drawbacks: i) the too fast translocation of single DNA molecules through a graphene nanodevice, and ii) the very large low frequency electronic noise presumably due to mechanical vibration of the free-standing graphene membrane in aqueous buffers. Both these phenomena prevent single nucleotide identification (at least compared to biological nanopores). The direct chemical functionalization of graphene film with functional polymeric hydrogels will i) induce electrostatic and chemical affinities between DNA and the functional polymer hydrogel and ii) stabilize mechanically graphene from vibrating. The host group of Dr. Schneider was the first to propose graphene nanopores as single molecule DNA sensors in 2010 and has gained a lot of experience in this field. Dr. Schneider\u2019s group is now approaching DNA sequencing with graphene nanostructures with a strong chemistry component. Schneider\u2019s lab in Leiden is therefore, at the moment, the best place in the world to make this research proposal a success. I do believe this proposal has the potential to lead toward ground-breaking applications in nanopore-based biosensors, particularly for high throughput next generation sequencing applications with graphene nanogaps.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["749671"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["Asociacion - Centro de Investigacion Cooperativa en Nanociencias - CIC NANOGUNE"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Device oriented molecular spin filter based interfaces"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["DELICE"], "Technology_Description": "We live in a constantly changing society in which information and communication are at the basis of our economy. To keep progressing is essential to investigate new feasible ways to control and manipulate information in order to develop faster, smaller and less consuming devices. Organic Spintronics has emerged as a promising field to develop low-cost, mechanically-flexible and multi-functional devices in which information is carried not only by the charge but also by the spin of electrons. However, the injection and transport of the spin information through a device remains challenging, being organic/inorganic interfaces key to overcome this limitation. DELICE addresses the interface engineering in organic spintronics, aiming to profit from unique molecular capabilities for the development of highly performant chemically-tailored organic spintronic devices. In particular, DELICE focuses on exploiting the predicted spin filtering behavior of some organometallic molecules to obtain highly spin-polarized interfaces, enhancing the spin injection from ferromagnetic surface or even creating spin-polarization on non-magnetic metal surfaces. These so-called spinterfaces will be implemented in organic spintronic devices, spin valves, in order to determine the impact they have on the device performances. While organics have been mainly used as passive spacers in such devices, DELICE plans to go beyond the state of the art by actively exploiting the molecule\u2019s spin filtering capability to improve device performances. A thorough characterization of the spinterfaces properties together with their implementation in real devices will provide us with valuable knowledge about the role of interfaces in devices. The technological potential of such a result represents a major step towards the realization of competitive organic nanodevices. The ultimate goal of DELICE is offering an interdisciplinary training to a promising young female researcher.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["748459"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI PAVIA"], "EU_Contribution": ["EUR 168 277,20"], "Project_Title": ["Molecular characterization of vesicle tethering complexes as novel regulators of collagen trafficking"], "Total_Cost": ["EUR 168 277,20"], "Country": ["Italy"], "Project_ACR": ["COTETHERS"], "Technology_Description": "Collagen maturation (through post-translational modifications, quaternary assembly and transport) is critical for tissues and organ development and homeostasis. This complex process involves numerous actors in different sub-cellular compartments, which in turn depend on highly regulated trafficking systems. Although the mechanisms of vesicular trafficking, membrane tethering and fusion are conserved throughout eukaryotic evolution, highly specialized tethering complexes have evolved to regulate specific fusion events. Recently, a novel pathway regulating collagen trafficking has been identified. Central to this pathway are two trafficking proteins, homologous to, but not part of, classical vesicle tethering components. At present, very little is known about their specific functions. ", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["745934"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KARLSRUHER INSTITUT FUER TECHNOLOGIE"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Understanding the resilience of Amazonian floodplain ecosystems"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["RESILIENCE"], "Technology_Description": "The riparian forests that flank the major rivers in the Amazon Basin form a highly distinct ecosystem that connects the most biodiverse aquatic and terrestrial environments on the planet. These \u2018flood forests\u2019 are inundated for periods of up to six months each year. But although submerged part of the year, flood forests are susceptible to forest fires during the dry season, especially in El Ni\u00f1o (ENSO) drought years. Surprisingly, flood forests poorly regenerate after burning, and after repeated burning can transition to a savanna-like state in which the forest appears unable to regenerate altogether. Our previous field surveys and experiments suggest that seed dispersal limitations may play a fundamental role in understanding the resilience of flood forests to fire perturbations. Fire destroys the seed bank completely. We hypothesise that forest regeneration is arrested by limited seed dispersal as burnt treeless stands affect fish communities and the capacity to retain incoming seeds. Amazonian fishes heavily exploit flood forests during the rainy season. Most flood forest trees produce fruits and seeds during the time of high water, coinciding with the arrival of fishes. Fishes may play an important role as dispersal agents for flood forest trees, as tree seeds have been found in the stomachs of >200 fish species. The reduced input of seeds in burned areas suggests that fishes avoid entering these sites, resulting in a positive feedback that helps to keep these areas in a state of sparse tree cover. In the proposed research, we will assess the ecological barriers that explain arrested regeneration of Amazonian flood forests by evaluating the pathways of seed dispersal and the effects of fire on the composition and abundance of fish communities. Understanding the regeneration of flood forests after fire will become increasingly relevant as extreme ENSO drought events and their associated fires are predicted to become more frequent.", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["746181"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Astroglial control of axonal excitability, adaptation and analogue signalling"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["AstroModulation"], "Technology_Description": "Evidence has been emerging for astrocytes to play an important role in neuronal cooperation and information processing in the brain. Recent work has suggested that their activity may even regulate the shape of action potentials in the axon and thus the efficacy of synaptic transmission. However, the underlying physiological machinery remains poorly understood. We propose here that astrocytes play an active role in the analogue-digital regulation of presynaptic signalling. To decipher the role of astroglia in presynaptic signalling, in particular analogue-digital axonal information transfer, we focus on the giant mossy-fibre-CA3 synapse, well characterized in the host laboratory. Our working hypothesis is that astrocytes regulate spike generation and propagation in axons by modulating local extracellular potassium and possibly by releasing glutamate. To test this hypothesis, an innovative set of technique will be used: i) direct recordings of astrocytes and either presynaptic or postsynaptic elements of the synapse in the mossy-fibre to CA3 synapse; ii) genetic tools allowing specific targeting and stimulation of either astrocytes or neurons; iii) pioneering imaging tools, such as FLIM, to directly measure the calcium entry and glutamate-sensing fluorescent reporter to reveal glutamate release by the astrocytes. The proposed project should unravel the mechanisms by which astrocytes control axonal information transfer in neural networks axonal excitability while shedding light on poorly understood features of astrocyte physiology.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["746247"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["DE MONTFORT UNIVERSITY"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Trust based Decision Support Systems for Social Networks with Uncertain Knowledge"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["DeciTrustNET"], "Technology_Description": "In real world decision-making, such as public security, social choice or recommender systems, we have a large body of data from various networked heterogeneous information sources or individuals that often conflict with each other and provide inconsistent knowledge. It is a challenging task to yield an optimal consensus decision, given the range of individual decisions obtained in terms of these knowledge sources. This research proposal aims to create a novel mathematical and computational framework for trust based social choice in networks and with uncertain knowledge by merging multiple individuals\u2019 preferences in an adaptive manner to reduce the disagreements among them, and automatically seek a decision or provide a recommendation with a maximal consensus. To achieve our goal, we propose to bring together, for the first time, four previously disparate strands of research: social network analysis, fuzzy preference modelling, multiple attribute group decision-making and game theoretic modelling of malicious users. As a showcase the proposed framework will be incorporated to an e-health recommender platform to increase healthy lifestyle in cancer survivors. ", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["746398"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITA CA' FOSCARI VENEZIA"], "EU_Contribution": ["EUR 180 277,20"], "Project_Title": ["The church of the Holy Apostles at Constantinople: the MYth and its Reception across the CEnturies"], "Total_Cost": ["EUR 180 277,20"], "Country": ["Italy"], "Project_ACR": ["MYRiCE"], "Technology_Description": "MYR", "To": ["2019-06-04, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-05"], "Project_ID": ["745869"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAET GRAZ"], "EU_Contribution": ["EUR 178 156,80"], "Project_Title": ["Forbush decrease model for expanding CMEs affecting Earth and Mars"], "Total_Cost": ["EUR 178 156,80"], "Country": ["Austria"], "Project_ACR": ["ForbMod"], "Technology_Description": "Solar storms, also known as coronal mass ejections (CMEs), are the strongest drivers of space weather. During planetary impacts, they cause short term decreases in the galactic cosmic ray (GCR) flux, called Forbush decreases (FDs). These depressions are observed in the interplanetary space, at the surface of the Earth and recently also on the Mars\u2019 surface by the Curiosity Rover. A large subset of FDs is caused by interplanetary flux ropes (FRs), which expand during their propagation based on observational studies.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["745782"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["At the host-bacteria interface: Modulation of the intestinal microbiota and its metabolic activity by Card9 signalling in health and Inflammatory Bowel Diseases"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["MArylAND"], "Technology_Description": "The microbial community in the human intestine is crucial to the health and nutrition of the host. Loss of the fragile balance within this complex ecosystem is involved in numerous pathologies, including inflammatory bowel disease (IBD). The incidence of IBD is increasing and affects individuals in challenging years of their lives, with immunosuppressive treatments that are not always effective. ", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2017-11-01"], "Project_ID": ["743576"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["AALTO-KORKEAKOULUSAATIO"], "EU_Contribution": ["EUR 179 325,60"], "Project_Title": ["Organic Polariton Laser Diode"], "Total_Cost": ["EUR 179 325,60"], "Country": ["Finland"], "Project_ACR": ["OPLD"], "Technology_Description": "The high current density required for population inversion in organic semiconductors has made the realization of an organic laser diode rather challenging. Here, I propose an organic polariton laser diode (OPLD) in which the threshold is achieved through the mechanism of polariton condensation. This conceptually different lasing mechanism does not require population inversion, suggesting that lasing under electrical injection can be, for the first time, demonstrated in organic semiconductors. To date, most commercial laser diodes are based on inorganic semiconductors, which are expensive materials, require complex fabrication and manufacturing processes, and have a limited range of lasing wavelengths. Organic semiconductors, in contrast, are ideal materials for the industrial production of diode lasers and other optoelectronic devices due to their ease of fabrication and processing, low acquisition-cost, and broad spectrum of emission. The realization of the first OPLD within this fellowship will be tremendously important for the European market. In 2014, diode-laser technology comprised 46% of the total revenue ($9.4 billion) in the global laser market. Moreover, emerging automotive lighting (BMW Laserlight) and high-definition laser display (LG LASER display) technologies could enable diode lasers to overtake the global laser market. Therefore, any steps towards the realization of the first organic laser diode (or organic solid state laser) would represent a significant technological and scientific achievement. Furthermore, the proposed device offers a totally new, due to its electrical pumping, platform for fundamental studies of quantum fluids of light.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["745115"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE DE GENEVE"], "EU_Contribution": ["EUR 175 419,60"], "Project_Title": ["Catalysis with Chalcogen Bonds: Toward Artificial Enzymes"], "Total_Cost": ["EUR 175 419,60"], "Country": ["Switzerland"], "Project_ACR": ["ChalEnz"], "Technology_Description": "Major advances in science and technology are arising from the discovery and exploitation of new non-covalent interactions between molecules and the development of novel supramolecular functional systems. However, a limited number of supramolecular interactions is available up to date. Therefore, the discovery of conceptually innovative, non-conventional approaches to create function should result in a breakthrough in current science. One of the most relevant functions that can be implemented in molecular and supramolecular systems is the ability to catalyse chemical processes. Thus, the goal of this proposal is the integration of unorthodox non-covalent interactions, up to date mainly studied as a concept, into practical applications in the field of catalysis. ", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["740288"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["VRIJE UNIVERSITEIT BRUSSEL"], "EU_Contribution": ["EUR 160 800"], "Project_Title": ["The European Commission in Drone Community: a New Cooperation Area in the Making"], "Total_Cost": ["EUR 160 800"], "Country": ["Belgium"], "Project_ACR": ["EU-Drones"], "Technology_Description": "The objective of this research is to examine how the European Commission is shaping regulatory framework development, production and use of drones considering the diverging interests among actors concerned in Europe (and beyond) where multiple authorities overlap. A comprehensive analysis of drones operations as a whole, including actors\u2019 perceptions, expectations, interests and practices is still lacking. This research will therefore study the European Commission\u2019s strategy to join and shape the drone community (rule makers, interest groups, manufacturers, operators and users) as well as the impact of its action. Referring to the Commission\u2019s policy entrepreneurship literature, it is interested in how the Commission, by building on its competencies and resources, has exercised its leadership capacity to initiate action in a new domain that may not fall de facto under its prerogatives and thus has an effect on a strategic industry. Based on a relational approach, the project will analyse the power structures (configuration of relations, diverging and converging interests, resources, skills), perceptions of issues at stake (discourses) and action rationale (cooperation dynamics, informal and formal practices, strategies and means) of actors involved in EU initiatives: the single drones market, the regulatory framework, as well as research and development. The research methodology will be qualitative and based on a triangulation of methods (documents, discourses and interviews analysis). In line with the researcher\u2019s previous work on the Commission\u2019s actions in the security sector, it will be argued that the Commission\u2019s leadership in drone matters, regarding its market, regulation and development, offers a lever for action to strengthen its position in the field of security at the crossroads between all actors involved as a bridge between the internal and external security, civil and military dimensions.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["747947"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI ROMA TRE"], "EU_Contribution": ["EUR 168 277,20"], "Project_Title": ["Historical Small Smart City Protocol for integrated interventions."], "Total_Cost": ["EUR 168 277,20"], "Country": ["Italy"], "Project_ACR": ["HISMACITY-pro"], "Technology_Description": "\"Over the last decade, the urban conservation challenge has grown critical due to rapid urbanization and the resulting growth and transformation of cities worldwide. Conserving historic urban environments is currently one of the most universally urgent and challenging cultural heritage conservation issues. The research project \"Hismacity-pro\" aims to develop a detailed protocol of multidisciplinary integrated interventions targeted at the recovery and revitalization of small historic centers by enabling smart city services, in order to improve the quality of life in these settlements, which are usually confined within marginal areas, far from the biggest cities. The protocol will be able to be replicated in other southern European towns with the same needs. At the moment, Italian small centers haven\u2019t been rigorously mapped and requalified and local policies aimed at their recovery are quite absent, while the Italian Agency for Territorial Cohesion has recently set up a central policy for their valorisation. The protocol will be adoptable by this strategy and will convey an operative tool of guidance for municipalities in peripheral areas on policy management, in central Italy and Catalonia (Spain). The research will be grounded in an holistic management of sites and their surrounding context and will encourage a considerable increase in the competitiveness of small historic centers, as well as their conservation and economic sustainable growth. The project will assess the state of information available to practitioners and identify unmet needs in the conservation of historic cities and urban settlements. It will also try to find a response to how small historic towns can use local assets to revitalize their economy, and the logic of turning problems into resources will be adopted (\u201csmart\u201d growth). The protocol will foster interventions tailored to the real needs of Euro-mediterranean historic small towns under marginal conditions.\"", "To": ["2019-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-12-01"], "Project_ID": ["743837"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["TECHNISCHE UNIVERSITAET MUENCHEN"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Dynamical Phenomena in Quantum Many-Body Systems"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["QMBDyn"], "Technology_Description": "We will study dynamical phenomena in strongly interacting quantum systems, which currently receive increased attention due to recent experimental, numerical and theoretical breakthroughs. Our research will push the limits of the state of the art of numerical simulations in this context by bringing together experts (the ER and the host group) on different aspects of this topic in an outstanding research environment in Munich with an excellent infrastructure and a clustering of theoretical and experimental groups with the potential to world class collaborations.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["747914"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF NATIONAL AND WORLD ECONOMY", "EKONOMICKA UNIVERZITA V BRATISLAVE", "INDUSTRIALEN KLASTER ELEKTROMOBILI", "Finance & Banking, Associazione per lo Sviluppo Organizzativo e delle Risorse Umane", "UNIVERSITA DEGLI STUDI ROMA TRE", "ARISTOTELIO PANEPISTIMIO THESSALONIKIS", "SLOVENSKA ASOCIACIA PRE ELEKTROMOBILITU"], "EU_Contribution": ["EUR 1 525 500"], "Project_Title": ["Electromobility in urban transport: a multi-dimensional innovation (socio-economic and environmental effects)"], "Total_Cost": ["EUR 1 525 500"], "Country": ["Bulgaria", "Slovakia", "Bulgaria", "Italy", "Italy", "Greece", "Slovakia"], "Project_ACR": ["eMobilita"], "Technology_Description": "At present, transition towards electromobility in urban transport and related companies are among the most studied industrial areas. Different EU countries implement different methodological and business approaches to investigate the possibilities for the acceleration of electromobility integration in urban transport. Studies on these approaches to be shared within the project consortium and with different stakeholders (local authorities, producers of electric vehicles and recharging stations) will provide the basis of the initiative for increasing the interest in electromobility integration in urban transport as a multi-dimensional innovation. The thin red line of electromobility practical integration passes through the sharing of innovative ideas with relevant stakeholders by carrying out field studies, in-depth interviews and electronic on-line studies.", "To": ["2020-02-29, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Bulgaria"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other", "Other", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Other"], "From": ["2017-03-01"], "Project_ID": ["734459"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["UNIVERSITE DE GENEVE"], "EU_Contribution": ["EUR 265 840,20"], "Project_Title": ["Targeting CRISPR-based HDAC inhibitors to histones: a new tool for assessing mechanisms of class I HDAC inhibitors and developing chemical probes."], "Total_Cost": ["EUR 265 840,20"], "Country": ["Switzerland"], "Project_ACR": ["CRISTONE"], "Technology_Description": "Cancer is responsible for 8.5 million deaths worldwide each year, representing a considerable burden for society. In cancer cells, tumor repression genes are deactivated by epigenetic mechanisms. The accessibility of DNA to transcription factors is determined in part by the chemical modifications of histones, proteins that pack DNA into condensed chromatin. When histones are deacetylated by histone deacetylases (HDACs), the chromatin structure is even more packed, preventing gene expression. HDAC inhibitors are epigenetic drugs currently in the market, able to increase histone acetylation, unpacking DNA for gene transcription. However, the specific mechanisms leading to the success or failure of those drugs are poorly understood, leading to unpredictable therapeutic outcomes. HDAC inhibitors are expected to interact with HDACs in the cell nucleus. However, fluorescence-labeling has revealed HDAC inhibitors to locate mostly outside the nucleus in living cells, suggesting that their genomic effects represent only part of their activities. This project aims at developing a set of tools, using a modified genome-editing method and a fluorescent chemical probe combined with genome-wide assays to understand specifically the genomic mechanisms of HDAC inhibitors. We will develop the CRISTONE (CRISPR-based HDAC inhibitor targeted to histones) tool to allow targeted HDAC inhibition. We will target an HDAC1 inhibitor (a histone tail peptide) specifically to repressed loci in the genome of HDAC1-overexpressing HEK 293T cells. To understanding the transcriptional consequences of targeted and untargeted HDAC1 inhibition, the CRISTONE effects will be compared to those of a new fluorescent chemical probe capable of inhibiting nuclear HDACs. To assess the cellular phenotypic outcome, we will test the genome-wide cellular effects on transcription and chromatin accessibility, giving insights into the specific effects of genomic, targeted HDAC inhibition.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["750190"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FONDAZIONE TELETHON", "FONDAZIONE TELETHON"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Developing a cure for retinitis pigmentosa due to Usher syndrome"], "Total_Cost": ["EUR 150 000"], "Country": ["Italy", "Italy"], "Project_ACR": ["GeneVision"], "Technology_Description": "The GeneVision proof-of-concept project spins from a major discovery made by the principle investigator (PI) within the RetGeneTx ERC project demonstrating that dual AAV vectors expand AAV DNA transfer capacity in the retina thus allowing delivery of genes whose size cannot be packaged in single AAVs. Thus, dual AAV vectors allow gene therapy of those inherited blinding conditions, like Usher syndrome type Ib (USHIB), Stargardt disease or other forms of retinitis pigmentosa, due to mutations in large genes from which the AAV platform, the best to date for in vivo gene therapy, was so far precluded. ", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-04-01"], "Project_ID": ["755075"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["UNIVERSITE DE LIEGE", "UNIVERSITE DE LIEGE"], "EU_Contribution": ["EUR 147 000"], "Project_Title": ["NI2D: Software for nonlinear vibration analysis: From identification to design."], "Total_Cost": ["EUR 147 000"], "Country": ["Belgium", "Belgium"], "Project_ACR": ["NI2D"], "Technology_Description": "Nonlinear vibrations are a frequent occurrence in engineering structures and can originate from friction, contact, material laws and large displacements. Nonlinear phenomena are most often ignored or avoided in industry, because practitioners lack both a methodology and a software for properly addressing them.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["737610"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["From Neurons to Robots: Non-Invasive, General-Purpose Interfacing With Human Spinal Motor Neurons"], "Total_Cost": ["EUR 150 000"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["INTERSPINE"], "Technology_Description": "INTERSPINE (\u201cFrom Neurons to Robots: Non-Invasive, General-Purpose Interfacing With Human Spinal Motor Neurons\u201d) aims at exploiting the methodologies developed during the ERC Advanced grant DEMOVE (\u201cDecoding the Neural Code of Human Movements for a New Generation of Man-machine Interfaces\u201d). During DEMOVE, novel bioelectrodes and computational methods have been developed to enrich our fundamental understanding of the mechanisms underlying the generation of human movements, from the cellular level to the function. These methods also contributed to the development of new schemes for controlling bionic limbs to substitute missing ones in amputees. INTERSPINE will translate these methods, and specifically those based on non-implanted electrodes, to develop a more robust general system that extracts neural information (at the individual cell level) from the human spinal cord and transforms it into extremely accurate commands to external devices, such as prosthesis, general purpose and teleoperated robots, and computer interfaces. This will be the only non-invasive man-machine interface based on direct neural activity (spiking of neural cells). The ERC Grant DEMOVE demonstrated in laboratory conditions that this approach is feasible and allows the identification of the exact timing of each activation of neural cells in the spinal cord, known as motor neurons. INTERSPINE will extend this approach through wearable devices and real-time processing, as well as with a robust association between the identified neural activity and external commands to devices, with the aim of revolutionizing everyday man-machine interfacing. The direct decoding of neural activity will provide unprecedented accuracy and robustness with respect to other non-invasive approaches.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["737570"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["KING'S COLLEGE LONDON", "KING'S COLLEGE LONDON"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Functions of plasticity in adult-born neurons"], "Total_Cost": ["EUR 2 000 000"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["FUNCOPLAN"], "Technology_Description": "The major objective of FUNCOPLAN is to examine groundbreaking questions on the functional role of newly-generated neurons in the adult brain. Using a combination of innovative approaches, our aim is to discover how plasticity in adult-born cells shapes information processing in neuronal circuits.", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["725729"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["DEUTSCHES ZENTRUM FUR NEURODEGENERATIVE ERKRANKUNGEN EV", "DEUTSCHES ZENTRUM FUR NEURODEGENERATIVE ERKRANKUNGEN EV"], "EU_Contribution": ["EUR 1 806 068"], "Project_Title": ["Dendritic encoding of movement in space"], "Total_Cost": ["EUR 1 806 068"], "Country": ["Germany", "Germany"], "Project_ACR": ["SUBDECODE"], "Technology_Description": "Understanding the neuronal basis of behaviour is a central quest for neuroscience. Neurons are the fundamental units of computation in the brain. Thus, any attempt at unravelling the relationship of neural networks activity and behaviour must be based on an understanding of the transformation of inputs to outputs in single neurons. One of the greatest challenges that our field faces is to make sense of inputs. Without knowing how different synaptic inputs are engaged during behaviour, it is impossible to decode the neuronal input to output conversion. We have developed an approach that allows both the dissection of inputs and the prediction of output during behaviour. We will apply this functional decoding approach to pyramidal neurons in the dorsal subiculum. These neurons form a hippocampal-neocortical interface and are important for memory-guided navigation. The output of subicular neurons contains a dense, distributed representation of space, but the functional input diversity is unresolved. Following the generation of a spatial tuning map during navigational tasks with two-photon Ca2+ imaging at cellular-resolution, we will map the input origins of individual neurons by using targeted single-cell initiated mono-transsynaptic tracing. Then, we will dissect the function of the input from different origins by chemogenetic silencing of input synapses. As a central component of the project, we will map dendritic input patterns in navigating mice with two-photon imaging of Ca2+ transients on dendritic spines. These patterns will be incorporated into a data-driven biophysical model capable of converting realistic synaptic inputs into output. We will tune the model parameters using whole-cell patch-clamp recordings during free behaviour. The final models will be capable of predicting the membrane potential of subicular neurons from precise behavioural observations, offering exciting new perspectives for network analysis and neuroengineering.", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-05-01"], "Project_ID": ["725693"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["MEDICAL RESEARCH COUNCIL", "MEDICAL RESEARCH COUNCIL"], "EU_Contribution": ["EUR 1 990 125"], "Project_Title": ["Understanding the complexity and architecture in protein ubiquitination"], "Total_Cost": ["EUR 1 990 125"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["UbiArchitect"], "Technology_Description": "The posttranslational modification of proteins with polyubiquitin regulates virtually all aspects of cell biology. This versatility arises from eight distinct linkage types between individual ubiquitin moieties in polyubiquitin, which co-exist in cells, are independently regulated, and eventually determine the fate of the modified protein. However, ubiquitin chain architecture can be highly complex, and the extent of \u2018chain branching\u2019 is unknown. Moreover, ubiquitin also undergoes phosphorylation and acetylation, which can dramatically alter its function. ", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-10-01"], "Project_ID": ["724804"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITEIT UTRECHT", "UNIVERSITEIT UTRECHT"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["The Senses of Islam: A Cultural History of Perception in the Muslim World"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["SENSIS"], "Technology_Description": "The aim of SENSIS is to write a cultural history of the senses in Islam, by examining how the senses have been conceptualised, and calibrated, in a variety of Muslim environments. Sensory perception is not only a physical but also a cultural act: how people experience and understand sight, sound, smell, taste, and touch differs according to the historical, geographical, social and intellectual contexts in which perception occurs. Accordingly, this project comprehensively studies the Muslim sensorium, past and present.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["724951"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["TARTU ULIKOOL"], "EU_Contribution": ["EUR 136 582,80"], "Project_Title": ["Patterns and management of ethnic relations in the Western Balkans and the Baltic States"], "Total_Cost": ["EUR 136 582,80"], "Country": ["Estonia"], "Project_ACR": ["MERWBKBS"], "Technology_Description": "\u2018Patterns and management of ethnic relations in the Western Balkans and the Baltic States\u2019", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Estonia"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["749400"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE PARIS DIDEROT - PARIS 7", "UNIVERSITE PARIS DIDEROT - PARIS 7"], "EU_Contribution": ["EUR 2 198 150,99"], "Project_Title": ["Smart Lab-On-Chips for the Real -Time Control of Cells"], "Total_Cost": ["EUR 2 198 150,99"], "Country": ["France", "France"], "Project_ACR": ["SmartCells"], "Technology_Description": "Cells are complex, autonomous genetic machines with rich information processing capabilities. Synthetic Biology builds on these properties to design novel, synthetic genetic programs in cells with the aim of benefiting humans. Yet, safety and efficiency issues require creation of synthetic circuits that are reliable over a large range of operating conditions and stable to all sorts of perturbations. This is a tremendous challenge for synthetic biologists, as the robustness of any circuit is limited by their high dependence on the cellular host machinery and the fundamental stochastic nature of gene expression. Taking inspiration from physics and engineering we have imagined a computer-based feedback loop that can remotely, in real-time, control the state of a synthetic genetic program running in cells. Here, we will combine microfluidics, optogenetics, structured illumination, inference methods and control algorithm into such a real time control device of gene expression for yeast cells. We will then study how cells can be controlled at different scales and with increasing levels of complexity from a simple circuit to a simple multicellular ecosystem. Specifically, we aim at:", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["724813"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS"], "EU_Contribution": ["EUR 276 107,40"], "Project_Title": ["Innovation through co-creation in contemporary mining relations: a new paradigm for stakeholder engagement at resource extraction project"], "Total_Cost": ["EUR 276 107,40"], "Country": ["United Kingdom"], "Project_ACR": ["CC4M"], "Technology_Description": "This research project and training programme explore the contemporary practice and future potential of co-creation models in stakeholder engagement, and seek to define a new paradigm and design a new model for sustainable resource relations in the mining industry. The call will generate cooperation between University of Queensland\u2019s Centre for Social Responsibility in Mining, a globally recognised hub of innovation and research excellence into resource relations, and University of St Andrews\u2019 Centre for Pacific Studies, one of Europe\u2019s leading research institutions with focus on the Pacific and, responding to the need for European expertise, will create new sites for European innovation and action in the crucially important context of resource relations. The proposed research project will use an interdisciplinary toolkit of research methods capable of reaching and engaging comprehensively with a wide spectrum of corporate, indigenous and increasingly influential \u2018virtual\u2019 stakeholders at mining projects in Papua New Guinea, uniquely mediating the nexus of resource host, industry and academy and moving beyond the dominant paradigm in resource relations. It will disrupt a series of well-established preconceptions about the nature of relations between stakeholders in resource contexts, identify new spaces for industry innovation, and propose new, more responsible and sustainable solutions to stakeholder engagement at mining projects. This project carries real potential to influence corporate and industry policies and actions, contributing to successful agreement making and Sustainable Development outcomes in resource relations.", "To": ["2020-08-06, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-07"], "Project_ID": ["753272"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 999 780"], "Project_Title": ["Epigenomics and chromosome architecture one cell at a time"], "Total_Cost": ["EUR 1 999 780"], "Country": ["France", "France"], "Project_ACR": ["EpiScope"], "Technology_Description": "In Eukaryotes, cellular identity and tissue-specific functions are linked to the epigenetic landscape and the multi-scale architecture of the genome. The packing of DNA into nucleosomes at the ~100 bp scale and the organization of whole chromosomes into functional territories within the nucleus are well documented. At an intermediate scale, chromosomes are organised in megabase to sub-megabase structures called Topologically Associating Domains (TADs). Critically, TADs are highly correlated to patterns of epigenetic marks determining the transcriptional state of the genes they encompass. Until now, the lack of efficient technologies to map chromosome architecture and epigenetic marks at the single-cell level have limited our understanding of the molecular actors and mechanisms implicated in the establishment and maintenance of the multi-scale architecture of chromosomes and epigenetic states, and the interplay between this architecture and other nuclear functions such as transcription.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["724429"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITEIT UTRECHT", "UNIVERSITEIT UTRECHT"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Cooperative Acceptor Ligands for Catalysis with Earth-Abundant Metals"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["CALCEAM"], "Technology_Description": "Homogeneous catalysis is of prime importance for the selective synthesis of high added value chemicals. Many of the currently available catalysts rely on noble metals (Ru, Os, Rh, Ir, Pd, Pt), which suffer from a high toxicity and environmental impact in addition to their high cost, calling for the development of new systems based on first-row transition metals (Mn, Fe, Co, Ni, Cu). The historical paradigm for catalyst design, i.e. one or more donor ligands giving electron density to stabilize a metal center and tune its reactivity, is currently being challenged by the development of acceptor ligands that mostly withdraw electron density from the metal center upon binding. In the last decade, such ligands \u2013 mostly based on boron and heavier main-group elements \u2013 have evolved from a structural curiosity to a powerful tool in designing new reactive units for homogeneous catalysis. ", "To": ["2022-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["715060"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["UNIVERSITEIT LEIDEN", "UNIVERSITEIT LEIDEN"], "EU_Contribution": ["EUR 1 499 853"], "Project_Title": ["Lost in Transition? Multiple Interests in Contexts of Education, Leisure and Work"], "Total_Cost": ["EUR 1 499 853"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["INTERESTS"], "Technology_Description": "\u201cI am going to graduate! But what exactly should I do next?\u201d All adolescents face this question when moving to postsecondary education or early career. Essential for sustainable choices in education and career is consolidating one\u2019s interest. Yet, exactly this step appears to be difficult, with many adolescents feeling lost, switching programmes, or regretting their choices afterwards. ", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["716183"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["ACADEMISCH ZIEKENHUIS LEIDEN", "ACADEMISCH ZIEKENHUIS LEIDEN"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Rheumatoid Arthritis Caught Early: investigating biological mechanisms preceding chronification of joint inflammation to identify patients prior to presentation of classic chronic arthritis"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["RACE"], "Technology_Description": "Rheumatoid Arthritis (RA) causes long lasting disability. At the time of clinically evident arthritis and diagnosis, the disease is already persisting, requiring long-term suppressive treatment. My overarching aim is to prevent chronic arthritis and RA by inhibiting the evolving auto-immune response in a pre-arthritis phase. Currently, identification of RA-patients before the classic presentation with clinically evident chronic arthritis is beyond the state of the art. I here aim to achieve this early recognition by increasing the mechanistic understanding of pre-arthritis phases.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["714312"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["SWANSEA UNIVERSITY", "SWANSEA UNIVERSITY"], "EU_Contribution": ["EUR 1 996 042,50"], "Project_Title": ["The true costs of bird flight: From the laboratory to the field"], "Total_Cost": ["EUR 1 996 042,50"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["FLIGHT"], "Technology_Description": "Flight is thought to be one of the most energetically costly of bird activities. These costs matter by virtue of their magnitude, as factors affecting flight costs can have a disproportionate impact on the overall energy balance. Flight costs are fundamentally linked to airflows, as well as behavioural responses to them, because birds react to horizontal and vertical currents by changing flight mode (i.e. flapping/ gliding), speed and route. Even minor route adjustments can radically affect the flow conditions that birds experience due to the uniquely dynamic and heterogeneous nature of the aerial environment. Yet our understanding of how airflows impact birds is in its infancy, being constrained by a lack of information on the metabolic costs of flight. Currently, the main methods for measuring flight costs in the laboratory either restrain the bird (thereby increasing energy expenditure) or suffer from low resolution, and field methods do not allow costs to be resolved in relation to fine scale movement paths. FLIGHT will use interdisciplinary approaches, integrating laboratory and field techniques, to address these grand challenges. Breakthrough methodologies will be used to (1) measure the costs of unrestrained bird flight in the laboratory and (2) derive a new proxy for power use in flight that is linked to flight performance, using accelerometry measurements from cutting-edge data loggers. Loggers will then be (3) deployed on wild birds to quantify their responses to airflows and the energetic consequences over fine scales. This will provide completely novel, mechanistic insight into the way the physical environment impacts flight costs, and (4) enable variation in flight\u2013related energy expenditure to be modelled geographically and seasonally in model species. Overall, FLIGHT will provide new macro-ecological insight into relationships between bird distributions and flow conditions and inform assessments of how birds may be affected by changing wind regimes.", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["715874"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["UNIVERSITY OF KEELE", "UNIVERSITY OF KEELE"], "EU_Contribution": ["EUR 1 998 696"], "Project_Title": ["DNA dynamics in the unusual cell cycle of the malaria parasite Plasmodium falciparum"], "Total_Cost": ["EUR 1 998 696"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["PlasmoCycle"], "Technology_Description": "This proposal promises to transform our understanding of the basic biology of the malaria parasite Plasmodium, and of how that biology affects virulence. Remarkably little is known about the Plasmodium cell cycle, despite a wealth of knowledge on the subject in model cells. This project will reveal, with unprecedented resolution, how DNA replication is organised in Plasmodium and how changing conditions in the human host and exposure to antimalarial drugs affect it. ", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["725126"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI ROMA TRE", "UNIVERSITA DEGLI STUDI ROMA TRE"], "EU_Contribution": ["EUR 1 235 875"], "Project_Title": ["Universality in Condensed Matter and Statistical Mechanics"], "Total_Cost": ["EUR 1 235 875"], "Country": ["Italy", "Italy"], "Project_ACR": ["UniCoSM"], "Technology_Description": "Universality is a central concept in several branches of mathematics and physics. In the broad context of statistical mechanics and condensed matter, it refers to the independence of certain key observables from the microscopic details of the system. Remarkable examples of this phenomenon are: the universality of the scaling theory at a second order phase transition, at a quantum critical point, or in a phase with broken continuous symmetry; the quantization of the conductivity in interacting or disordered quantum many-body systems; the equivalence between bulk and edge transport coefficients. Notwithstanding the striking evidence for the validity of the universality hypothesis in these and many other settings, a fundamental understanding of these phenomena is still lacking, particularly in the case of interacting systems. ", "To": ["2022-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-03-01"], "Project_ID": ["724939"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["THE UNIVERSITY OF WARWICK"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Sparse Robust Expander with Applications in Combinatorial Embedding Problems"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SREACEP"], "Technology_Description": "Expanders is a fundamental concept in combinatorics. From the application point of view, expanders have become a powerful tool in studying real life problems such as network design and error correcting codes. From the theoretical point of view, it is considered as a sparse analogue of Szemeredi's regularity (recognised by the 2012 Abel prize) with connections in algebra, analysis, geometry and topology.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["752426"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CARL VON OSSIETZKY UNIVERSITAET OLDENBURG", "CARL VON OSSIETZKY UNIVERSITAET OLDENBURG"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Individualized Binaural Diagnostics and Technology"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["IBiDT"], "Technology_Description": "Humans have two ears \u2013 and for good reason: So-called binaural hearing is critical not only for localizing acoustic events but also for selectively focusing on a target sound while suppressing sound from other directions. In order to perform these tasks, neural circuits with the most temporally precise processing within the entire nervous system have evolved.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["716800"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 200 194,80"], "Project_Title": ["Expert Rule? Judges, Lawyers, and the Practices of Interpretation in International Criminal Law"], "Total_Cost": ["EUR 200 194,80"], "Country": ["Denmark"], "Project_ACR": ["EaRL"], "Technology_Description": "Since the end of the Cold War, the number of international courts has increased significantly, indicating a growing judicialisation of global governance. At the same time, international judges have begun to change and potentially even create law through their decisions. In international criminal law, a particularly drastic example, international judges repeatedly described the development of international criminal law as one of their main achievements. But have these courts, 15 years after the Rome Statute of the International Criminal Court entered into force, been able to deliver on their objective? How far do judicial interpretations matter in global governance more broadly? Applying an innovative interdisciplinary approach that draws on legal theory, this project (EaRL) capitalises on the recent \u201cpractice turn\u201d in International Relations theory to develop a novel theoretical and empirical account of interpretive judicial authority in global governance. EaRL is based on a systematic analysis of all 240 available judgements of international criminal and hybrid courts, including the International Criminal Court, the ad hoc Tribunals for the former Yugoslavia (ICTY) and Rwanda (ICTR), and the Special Court for Sierra Leone (SCSL). In addition, it uses over 40 in-depth expert interviews with international judges, staff at civil society organisations, and government representatives. Ideally located at iCourts, the University of Copenhagen\u2019s globally leading Centre of Excellence for International Courts, EaRL will enable the experienced researcher to complete her interdisciplinary training and to make a timely contribution to the Centre\u2019s impressive body of knowledge on international courts. In addition to its academic impact, EaRL ultimately aims to enhance the judgement-writing process at international criminal courts and to improve the general public\u2019s understanding of international criminal justice.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["748114"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CONSIGLIO NAZIONALE DELLE RICERCHE"], "EU_Contribution": ["EUR 180 277,20"], "Project_Title": ["EXTREME ENVIRONMENT RESISTANT NANOPHOTONICS"], "Total_Cost": ["EUR 180 277,20"], "Country": ["Italy"], "Project_ACR": ["EXTREMELIGHT"], "Technology_Description": "Nanophotonic extreme environment sensors are expected to lead to revolutionary advancements in aerospace, nuclear, wellbore exploration and environmental bio-chemical sciences. Extreme environments are those where the physico-chemical conditions render standard materials completely unusable; including strongly ionizing radiation, high erosion, high corrosion, or temperatures beyond 1600\u00b0C in aircraft and aerospace applications. Recently, yttrium aluminum garnet (YAG) crystals have been identified as harsh environment resistant optical material thanks to its unique combination of outstanding optical properties and high melting temperature (1970\u00b0C), chemical inertness and hardness. It\u00b4s use for developing extreme environment nanophotonic on-chip instruments is therefore of high interest. However, micro/nanostructuring YAG crystalline components is currently impossible due to its capability to withstand corrosion in plasma etching chambers, its hardness, and its fracturing under high micro-stress loading machining or milling industrial processes. The central question that this project aims to solve is:", "To": ["2019-05-01, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations"], "From": ["2017-05-02"], "Project_ID": ["747055"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF WARWICK"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Galois Representations and Diophantine Problems"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["GalRepsDiophantine"], "Technology_Description": "Wiles' remarkable proof of Fermat's Last Theorem paved the way for the modular approach to Diophantine equations. This associates a Frey elliptic curve to a putative solution of a Diophantine equation and studies it using Galois representations and modularity. This proposal is organized around two research programmes, both of which develop new tools for the modular approach. The first is concerned with distinguishing Galois representations; this is currently the most frequent obstruction to the success of the approach. The second aims to prove modularity and irreducibility theorems for abelian varieties of GL2 type. Such theorems are of tremendous independent interest, but will also allow the replacement of Frey elliptic curves with Frey abelian varieties giving the modular approach immense flexibility.", "To": ["2020-02-29, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["747808"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF WARWICK"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Birational and Tropical Methods in Geometry"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["BTMG"], "Technology_Description": "We propose major advances in several fundamental questions of algebraic geometry, centering around the invariants of varieties, that we will attack on two fronts. One direction considers birational invariants and rationality properties. The other studies deformation properties of varieties, especially in terms of curve-counting invariants. Accordingly, we divide the material into three main projects. In the first, we will prove rationality theorems for many new birational quotients obtained via divided powers. The second project sets up a novel method of counting tropical curves, that will lead to results on tropical correspondences. Our third project extends the ideas of the second, proving deep enumerative results in log geometry; we expect this to provide a state-of-the-art enumerative interpretation of the divisor-line bundle equivalence in log tropical terms. The University of Warwick is the ideal venue for this research. The PI will benefit from the extensive experience of Miles Reid and Christian B\u00f6hning, world experts in birational geometry and the modern study of rationality questions, and from collaboration with Diane Maclagan, an acknowledged authority in tropical geometry.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["746554"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["STICHTING KATHOLIEKE UNIVERSITEIT"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["Imaging the Motion of Magneto-Excitons in New Emerging Materials"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["IMME-NEM"], "Technology_Description": "Recently discovered two-dimensional (2D)-honeycomb semiconductor materials have two inequivalent, degenerate valleys in their electronic band structure. This leads to a new \u201cvalley\u201d degree of freedom known as pseudospin that, similar to real spin, has been proposed as an extra information carrier for new classes of electronic and optoelectronic devices. Monolayer transition-metal dichalcogenides (TMDs) are an important type of 2D material, in which, due to the strong 2D confinement and a reduced dielectric screening of the Coulomb interactions, electron-hole (e-h) correlations are extremely strong. This results in creation of e-h pairs (excitons) that are so strongly bound that excitonic effects completely dominate the optical properties of TMDs even up to room temperature. The pronounced excitonic effects in single-layer TMDs, therefore, provide a unique opportunity to investigate strong light-matter interactions associated with valley effects exhibiting exotic behaviour. However, the key fundamental question regarding the exact excitonic band structure, the valley-exciton energy-momentum (dispersion) relationship, and the corresponding excitonic transport properties, remains open. ", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["746762"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF SOUTHAMPTON", "UNIVERSITY OF SOUTHAMPTON"], "EU_Contribution": ["EUR 1 998 927,51"], "Project_Title": ["Mechanical Chirality: Synthesis, Properties and Applications at a New Horizon in Supramolecular Stereochemistry"], "Total_Cost": ["EUR 1 998 927,51"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["MechaniChiral"], "Technology_Description": "Molecular chirality is a central theme in chemistry; in 2015 approximately 13% of publications in J. Am. Chem. Soc. and 12% in Angew. Chem. concerned chirality. All previously studied forms of molecular asymmetry (central, axial, planar and helical chirality) have found applications throughout the sub-disciplines of chemistry including as catalysts, materials and sensors.", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["724987"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["CONSIGLIO NAZIONALE DELLE RICERCHE"], "EU_Contribution": ["EUR 168 277,20"], "Project_Title": ["Out-of-equilibrium nanophotonics"], "Total_Cost": ["EUR 168 277,20"], "Country": ["Italy"], "Project_ACR": ["OUTNANO"], "Technology_Description": "OUTNANO is about developing a new generation of nanophotonic devices by exploiting ultrafast dynamics of electrons driven out-of-equilibrium.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations"], "From": ["2017-10-01"], "Project_ID": ["746774"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITEIT GENT"], "EU_Contribution": ["EUR 172 800"], "Project_Title": ["Crowdsourcing Urban Sustainability Governance. Exploring innovative governance models for addressing urban sustainability through ICT-people interaction"], "Total_Cost": ["EUR 172 800"], "Country": ["Belgium"], "Project_ACR": ["CROWD_USG"], "Technology_Description": "The project explores the potential of crowdsourcing (an online, distributed problem-solving process for creative solutions", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["740191"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN"], "EU_Contribution": ["EUR 187 866"], "Project_Title": ["Investigation of adaptive design and rewiring of Survival-Apoptosis-Mitogenic (SAM) signalling transduction network"], "Total_Cost": ["EUR 187 866"], "Country": ["Ireland"], "Project_ACR": ["SAMNets"], "Technology_Description": "Cell life is not the property of any single protein or gene; rather it emerges from concerted actions of multiple molecules in cellular networks. Current proposal is focused on Signal Transduction Networks (STN) connecting the environment to cell responses. A major challenge is to understand how STN integrate and process environmental signals in a robust and reliable way and how they \u201ccompute\u201d cell fate decisions depending on genetic background. To answer this question, the study will be focused on three interconnecting STNs: the Survival (PI3K/PTEN/AKT), Apoptotic (RASSF1/MST/LATS) and Mitogenic (EGFR/RAS/RAF/MEK/ERK) pathways, the SAM network. In the scope of current proposal the methods of signalling network reconstruction will be improved and the SAM network topology will be reconstructed in the panel of cell lines. Based on available data and reconstructed network topology the mechanistic site-specific dynamic model of SAM network will be developed and validated. Model predictions of dependence of signalling outputs behaviour on different perturbations (like small molecule inhibitors and their combinations) and background (mutations and protein expression levels) will be validated. The signalling outputs will be experimentally correlated to the cell fate decisions.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["750688"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN"], "EU_Contribution": ["EUR 187 866"], "Project_Title": ["Childhood Self-Control, Social Conditions, and Adult Health"], "Total_Cost": ["EUR 187 866"], "Country": ["Ireland"], "Project_ACR": ["SELFCONTROLHEALTH"], "Technology_Description": "The capacity to delay gratification and control impulses emerges in childhood and may profoundly shape the lifestyle behaviours and resulting health conditions that afflict many and burden health systems across Europe and rest of the world. Childhood self-control appears to be malleable and as such has been identified by policy-makers as a key prevention target with potential long-run benefits. Yet, empirical evidence demonstrating links from early self-control to adult outcomes remains scarce. This Fellowship will inform estimates of the benefits of fostering self-control by drawing on under-exploited childhood self-control measures from six pre-existing large scale (N>1,000) prospective studies of individuals whose health behaviour and health has been tracked for up to 55 years. Already, using these incredible resources the applicant has identified how childhood self-control predicts population patterns of smoking and weight gain across life. He now aims to advance this work and the scientific literature by identifying: (i) the specific life-span health consequences of early self-control (e.g. biomarkers, chronic conditions, mortality rates), (ii) the key behavioural and socioeconomic pathways that explain these linkages, and (iii) the social conditions where self-control may have the greatest health impact. The Fellowship will both enrich and benefit from the strengths of the host institution in Childhood and Human Development research. Strong input from a world-leading researcher in this area, Prof. Richard Tremblay, will help enable the applicant to make a disciplinary shift from behavioural medicine to an integrated life-course perspective where adult health is viewed through the lens of child development. This interdisciplinary mobility coupled with a strong programme of advanced training will ensure the Fellowship rapidly advances both the applicant\u2019s career development and the exciting programme of work outlined in this proposal.", "To": ["2020-03-14, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-03-15"], "Project_ID": ["750169"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF EDINBURGH"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Deep Biosignatures on Mars and Earth"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["D BIOME"], "Technology_Description": "\"In recent decades, samples from mines and boreholes have revealed that our planet\u2019s biosphere extends several miles downwards into the crust. Pores and fissures far below the seafloor and land surface are populated by vast numbers of microorganisms, with broad economic and scientific implications. These implications reach as far as Mars, whose subsurface has provided a potentially habitable environment for billions of years, protected from the hostile conditions at the surface. Although Earth's modern-day \"\"deep biosphere\"\" is now the subject of a major global research effort, almost nothing is known about its variation across geological time, which may have been considerable and highly consequential for planetary biogeochemistry. This project will combine state-of-the-art analyses of fossil and chemical traces of deep life (\"\"deep biosignatures\"\") with experimental and modelling work to elucidate the abundance, activity and geological record of ancient subsurface life on Earth and its possible relevance for Mars. Dr McMahon\u2019s research at the UK Centre for Astrobiology (School of Physics and Astronomy, University of Edinburgh) will be directed towards four main objectives, as follows:", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["747877"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 212 194,80"], "Project_Title": ["Microfoundations of International Order"], "Total_Cost": ["EUR 212 194,80"], "Country": ["Denmark"], "Project_ACR": ["MICROFOUNDATIONS"], "Technology_Description": "\"This project aims to investigate the microfoundations of international order. How do international orders emerge? How are they imagined, created, and maintained? What will be the future of the current international order? These and other similar questions continue to be of interest for scholars of international relations (Bull 1977; Brooks and Wohlfort 2008; Ikenberry 2012; Kupchan 2012; Sorensen 2011; Dunne and Flockhart 2013; Zakaria 2008; Hurrell 2008; Schweller 2014; Miskimmon et.al. 2013). Most of this literature looks at the macro picture, dealing with structural factors such as distribution of power, differential economic development, changing patterns of interdependence, and demographics to explain why and how international orders came to be. However, the issue of microfoundations has been largely overlooked, if not totally ignored.", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["704626"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["FUNDACION CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III", "FUNDACION CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III"], "EU_Contribution": ["EUR 1 861 910"], "Project_Title": ["YOUNGatHEART: CARDIAC REJUVENATION BY EPIGENETIC REMODELLING"], "Total_Cost": ["EUR 1 861 910"], "Country": ["Spain", "Spain"], "Project_ACR": ["YOUNGatHEART"], "Technology_Description": "Aging poses the largest risk for cardiovascular disease (CVD) and is orchestrated, to some extent, by epigenetic changes. Despite the significant progress on many fronts in the cardiovascular field, non-inherited epigenetic regulation in cardiac aging and CVD remains unexplored. Dilated Cardiomyopathy (DCM) is a major contributor to healthcare costs and it is the leading indication for heart transplantation. We have recently discovered that adult cardiac-specific deletion of epigenetic regulator Bmi1 in mice induces DCM and heart failure. These unprecedented data support the idea that inadequate epigenetic regulation in adulthood is critical in CVD. In addition, our studies with parabiotic pairing of healthy and DCM-diagnosed mice show that the circulation of a healthy mouse significantly improve the cardiac performance of mouse with DCM. These ground-breaking discoveries suggest that DCM regression, or cardiac rejuvenation, is feasible in terms of epigenetic states. Therefore, YOUNGatHEART will unveil significant breakthrough on (1) how non-inherited epigenetic deregulation induces DCM and (2) how epigenetic remodeling reversed this process. For that, our challenges are: 1A. To decipher how aged-linked cardiac dysfunction contributes to CVD by identifying the epigenetic landscape regulating cardiac aging among species; 1B. To decode how epigenetic deregulation induces DCM by integrating clinical data and samples from DCM-transplanted patients with imaging, transcriptomic, proteomic, and functional approaches from DCM model; and, 2A. To identified systemic factors with anti-cardiomyopathic effects by systematic proteomic screenings after parabiosis and epigenome of the DCM hearts. In sum, YOUNGatHEART puts forward an ambitious but feasible and pioneering program to tackle the epigenetic hallmark in cardiac aging with the final aim (2B) of setting the molecular basis for future therapeutic interventions in CVD.", "To": ["2020-10-31, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2015-11-01"], "Project_ID": ["647670"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["Barcelonabeta Brain Research Center Foundation"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["The effect of pro-aging and pro-youthful blood factors in normal ageing and Alzheimer\u2019s disease: a multimodal approach"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["BioALFA"], "Technology_Description": "The overall aim of the planned research is to test whether pro-aging and pro-youthful blood factors are associated with cognitive performance and neuroimaging outcomes in normal ageing and in individuals at risk of Alzheimer\u2019s disease (AD), and whether this association is modified by lifestyle habits (e.g. exercise or diet) or genetic factors. Ageing is the most important risk factor for AD. However, the exact mechanism that link ageing and AD is still unknown and, up to now, potential therapies for AD by targeting ageing have been poorly explored. Thus, in the present project we aim to provide a better understanding of the link between ageing and AD by measuring in human blood those factors that have been found to be \u2018pro-youthful\u2019 (GDF-11) or \u2018pro-aging\u2019 (CCL2, CCL11 and CCL19) in experimental animal models, but have not been comprehensively studied in humans. For these purposes, we will first develop novel and highly specific and sensitive assays based on the state-of-the-art Simoa platform. Next, we will measure these factors in the participants of the ALFA (Alzheimer and Families) study, which is currently taking place in the Barcelona\u03b2eta Brain Research Centre (BBRC), the host institution of this project. The ALFA cohort is composed of 2743 cognitively healthy individuals (45 to 75 years old) from which comprehensive clinical, neuropsychological, neuroimaging, genetic and environmental and lifestyle factors data are already available. Measurements will be performed in two steps: a training cohort and a validation cohort. Finally, we will investigate the association of the levels of the pro-aging/pro-youthful blood factors with features known to be related to AD such as clinical and life-style variables, neuroimaging outcomes and signatures and genetic variables. Altogether, the results of this project will clarify whether those blood pro-aging or pro-youthful factors may become potential therapeutic targets in AD.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["752310"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE GRENOBLE ALPES", "UNIVERSITE GRENOBLE ALPES"], "EU_Contribution": ["EUR 1 498 840"], "Project_Title": ["The Neutron Electric Dipole Moment: pushing the precision to understand the matter-antimatter asymmetry"], "Total_Cost": ["EUR 1 498 840"], "Country": ["France", "France"], "Project_ACR": ["NEDM"], "Technology_Description": "The existence of a permanent electric dipole moment (EDM) of the neutron, or any subatomic particle, would have far reaching implications connecting particle physics with cosmology. Time reversal invariance and CP symmetry would be violated. A new fundamental interaction producing the EDM, that is, deforming the charge distribution inside the neutron, could also have generated the matter-antimatter asymmetry in the early Universe. After 60 years of evolution, techniques to measure the neutron EDM are now so evolved that experiments are sensitive to microphysics associated with an energy scale beyond that accessible at the LHC. This situation offers a high likelihood of discovery for the next generation of experiments. In the same time, any improvement in precision is technically challenging. The control of the magnetic field must surpass that of the state of the art of atomic magnetometers. The n2EDM project aims at improving the precision by an order of magnitude or more. Systematic effects need to be controlled at an unprecedented level. In particular, the use of a mercury co-magnetometer based on the precession of 199Hg spins induces a set of subtle false effects due to the relativistic motional field. ", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["716651"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["DEUTSCHES KREBSFORSCHUNGSZENTRUM", "DEUTSCHES KREBSFORSCHUNGSZENTRUM", "KAROLINSKA INSTITUTET", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 2 270 000"], "Project_Title": ["RNA EDITING IN HEALTH AND DISEASE"], "Total_Cost": ["EUR 2 270 000"], "Country": ["Germany", "Germany", "Sweden", "United Kingdom"], "Project_ACR": ["RNAEDIT"], "Technology_Description": "\"RNA editing is a type of programmed RNA sequence alteration that can result in a range of proteomic changes, from subtle fluctuations in output, to specific alterations in protein content. Editing is catalyzed by two classes of deaminases: those which convert adenosine to inosine (ADARs) and those which convert cytosine to uracil (APOBEC1). We have previously shown that APOBEC1-catalyzed editing in the transcriptome of macrophages leads to the generation of populations that are heterogeneous, and functionally diverse, enabling rapid population adaptation to different environmental settings. ", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["649019"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA", "UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA", "QUEEN MARY UNIVERSITY OF LONDON", "ISTITUTO NAZIONALE DI FISICA NUCLEARE"], "EU_Contribution": ["EUR 1 971 841"], "Project_Title": ["Uncovering New Phenomena at the TeV Scale With Top Quarks"], "Total_Cost": ["EUR 1 971 841"], "Country": ["Italy", "Italy", "United Kingdom", "Italy"], "Project_ACR": ["NPTEV-TQP2020"], "Technology_Description": "Our understanding of the subatomic world and of the very fabric of the space-time is encompassed in a theory which is the result of all past experimental observations and theoretical developments: the Standard Model of Particle Physics. Yet cosmological observations and theoretical arguments lead us to conclude that new phenomenology,", "To": ["2020-08-31, ongoing project |"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2015-09-01"], "Project_ID": ["648723"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["DANMARKS TEKNISKE UNIVERSITET", "UNIVERSITY OF KENT", "DUBLIN CITY UNIVERSITY", "ACIB GmbH", "RENTSCHLER BIOTECHNOLOGIE GMBH", "UCB PHARMA SA"], "EU_Contribution": ["EUR 4 044 793,68"], "Project_Title": ["Enhancing CHO by Mammalian Systems Biotechnology (eCHO systems)"], "Total_Cost": ["EUR 4 044 794,43"], "Country": ["Denmark", "United Kingdom", "Ireland", "Austria", "Germany", "Belgium"], "Project_ACR": ["eCHO Systems"], "Technology_Description": "Chinese hamster (CHO) ovary cells are the production host for a +50 billion \u20ac/yr biopharmaceuticals market. Current CHO production platforms dates to 1980 and are based primarily on media and process optimisation with little consideration to the optimization of the cellular machinery. Fortunately, with the recent sequencing of the CHO genome, an opportunity has opened to significantly advance the CHO platform. The benefit will be advanced production flexibility and a lower production cost.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["642663"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA", "UNIVERSITA DEGLI STUDI DELLA CAMPANIA LUIGI VANVITELLI", "CRANFIELD UNIVERSITY", "FYZIKALNY USTAV SLOVENSKEJ AKADEMIE VIED", "EXIS INNOVATION LTD"], "EU_Contribution": ["EUR 2 578 386"], "Project_Title": ["Hybrid Electric Energy Integrated Cluster concerning Renewable Fuels"], "Total_Cost": ["EUR 2 578 386"], "Country": ["Greece", "Italy", "United Kingdom", "Slovakia", "United Kingdom"], "Project_ACR": ["HELENIC-REF"], "Technology_Description": "The targeted breakthrough of the HELENIC-REF project refers to the establishment of a new sustainable methodology for the water thermolysis at temperatures below 300oC and the immediate corresponding production of energy or fuels. The method is based on our preliminary experimental evidence of water thermolysis at 286oC in the presence of Fe3O4 nanoporous catalytic thick films, with the sustainable maintenance of the catalyst due to a new reduction method based on Lorentz force electrons generated by a magnetic field in the vicinity of the electric current heating the semiconducting catalyst. The method is used for the production of hydrogen and oxygen, as well as of fuels in the presence of CO2 in order to reduce CO2 to CO or even to hydrocarbons, (like Synthetic Natural Gas \u2013 SNG) via methanation.", "To": ["2018-05-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-1-2014 - FET-Open research projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Greece"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-06-01"], "Project_ID": ["665318"], "Call_for_Proposal": ["H2020-FETOPEN-2014-2015-RIA"]}, -{"Partners": ["WEIZMANN INSTITUTE OF SCIENCE", "WEIZMANN INSTITUTE OF SCIENCE"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Growth detection and quantification (GDQ)"], "Total_Cost": ["EUR 150 000"], "Country": ["Israel", "Israel"], "Project_ACR": ["Prolifimeter"], "Technology_Description": "The growth rate of both bacterial and human cells has a central role in the clinical management of infectious diseases and malignancies. Virulent and aggressive bacterial strains have higher growth rates, which will decrease in response to successful treatment. Proliferation rates are also instrumental in the diagnosis, prognosis, and treatment of various cancer types, as the proliferation rate of human cells is one of the hallmarks of malignancy, evident by the widespread use of various proliferation indices such as mitotic figure counting, PCNA and Ki-67 antibodies. An integral part of cell growth is DNA replication; in mid-replication, each replicating cell will have a second, partial, currently synthesized genome. This creates variations in DNA copy-number along the genome across a population of cells from which growth-rate is inferable.\u2028 Based on our novel ERC-funded method, which accurately measures bacterial growth rates from metagenomic samples, we will further the development of our methods towards obtaining an entirely new facet of information about pathogens in infectious diseases, or an accurate estimation of tumor proliferation rates. Our approach is expected to be superior to the current state-of-the-art as sample preparation is simple and requires no immunological staining or examination by an experienced pathologist, increasing validity and reproducibility.", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["737419"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["UNIVERSITA CA' FOSCARI VENEZIA"], "EU_Contribution": ["EUR 168 277,20"], "Project_Title": ["Ancient scholarship on archaic Greek iambic poetry"], "Total_Cost": ["EUR 168 277,20"], "Country": ["Italy"], "Project_ACR": ["ASAGIP"], "Technology_Description": "The proposed research concerns ancient scholarship on archaic Greek iambic poetry from the Hellenistic to the Byzantine period. It investigates the history of such scholarship in its various embodiments (editions, commentaries, marginal annotations, monographs on individual topics, author- and genre-specific lexica, and others) and the aims, concerns, assumptions, and techniques that it deployed. This investigation - the first of its kind - aims to contextualise such items of scholarship, and scholarship on iambos generally, within the broader picture of ancient literary scholarship. The study of ancient scholarship is a budding field, making the proposed research timely as well as necessary. Ancient scholarship has long been among my research interests. Given the Department's strengths on archaic Greek poetry and ancient scholarship, and Ca' Foscari's commitment to fostering research and supporting young researchers' skills development, Venice is the ideal partner for the success of the proposed research. Holding a Marie Sklodowska-Curie would be highly beneficial to my academic career and enable me to achieve independence as a professional researcher.", "To": ["2018-10-02, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-10-03"], "Project_ID": ["708556"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["KUNGLIGA TEKNISKA HOEGSKOLAN"], "EU_Contribution": ["EUR 173 857,20"], "Project_Title": ["Single-Photon Non-Locality"], "Total_Cost": ["EUR 173 857,20"], "Country": ["Sweden"], "Project_ACR": ["SiPhoN"], "Technology_Description": "The principle of non-locality is one of the most impressive features of quantum mechanics. Usually, non-locality is related to two or more particles sharing a common characteristic. This quantum mechanical effect is well understood and several experimental demonstrations have been performed. However, non-locality of a single particle, in particular of a single-photon raises fundamental questions: Can a single-photon be simultaneously at different locations? In spite of numerous theoretical concepts, no clear experiment has yet been reported.", "To": ["2017-10-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-11-01"], "Project_ID": ["661416"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["EUROPEAN NETWORK ON INDEPENDENT LIVING BRUSSELS OFFICE"], "EU_Contribution": ["EUR 140 994"], "Project_Title": ["USER-LED PERSONAL ASSISTANCE IN THE EUROPEAN UNION: A CRITICAL COMPARATIVE ANALYSIS"], "Total_Cost": ["EUR 140 994"], "Country": ["Belgium"], "Project_ACR": ["ULPA"], "Technology_Description": "This research will compare and evaluate User-Led Personal Assistance (ULPA) schemes for disabled people across the European Union. ULPA schemes will be approached from the perspective of the Independent Living philosophy and the social model of disability in order to evaluate their potential to equalise disabled peoples participation in social life. The research will be hosted by the European Network on Independent Living, a leading advocate for ULPA in Europe. Through its membership network, the organisation will enable the researcher to seek advice and feedback from disabled people\u2019s organisations, thus facilitating a participatory approach to research. The main outcomes will be a bespoke framework for normative evaluation of ULPA and a collection of best practices in ULPA in the European Union. These outcomes will benefit disabled people, their organisations, practitioners and policy makers working on European disability policy. Overall, the research will contribute to processes of European integration towards the building of barrier-free Europe for all.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-SE - Society and Enterprise panel"], "Coordinated_in": ["Belgium"], "Activity": ["Other"], "From": ["2017-05-01"], "Project_ID": ["747027"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSIDAD POMPEU FABRA"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Global Policy Uncertainty and International Asset Markets"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["GlobalPolicyUncertainty"], "Technology_Description": "Government policies - fiscal, monetary, and regulatory - define the rules of the game for economic agents. However, uncertainty about policy changes may affect the economy adversely as it acts as an additional source of risk. In an interconnected world economy, policy uncertainty has spillover effects beyond national borders, and becomes a global source of risk. In this context, this project investigates the relationship between global policy uncertainty - the common driver of uncertainty across countries - and international financial markets. In the aftermath of the financial crisis, it is timely and relevant to deepen our understanding of these relationships. This may, in turn, inform the development of policies that minimize the adverse impacts of uncertainty, particularly in regions of high economic integration as the Euro zone. ", "To": ["2018-09-21, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-22"], "Project_ID": ["705686"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSIDAD POMPEU FABRA"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Speech-sound Processing in Infant Development and Evolution"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["SPIDE"], "Technology_Description": "\"What are the uniquely human mechanisms of language acquisition that enable infants to start discovering the words and structures of their native language by the end of their first year? Language is undoubtedly a specifically human function, but it is crucial to disentangle between human-specific vs. general-processing skills that allow language acquisition. This project aims at exploring the developmental and evolutionary origins of one of the features of speech processing: the ability to assign specific functional roles to the different categories of sounds composing speech. Indeed, there is a Consonant/Vowel functional asymmetry in the world's languages as well as in speech processing, whereby consonants better fit the requirements of lexical processing (e.g. when writing abbreviations we tend to remove vowels and keep consonants to avoid compromising meaning, as in txt msgng), while vowels are better targets for syntax-related processes. It remains unknown where this \"division of labour\" comes from: uniquely human predisposition playing a role in early syntax and lexical acquisition, or consequence of the asymmetry present in the input? ", "To": ["2018-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["707996"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSIDAD POMPEU FABRA"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["The Early Peopling of Amazonia and the Beginning of Plant Domestication"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["EPP-Am"], "Technology_Description": "This project investigates two relevant, inter-related and multi-disciplinary topics in the prehistory of the Neotropic: 1) the social-ecological dynamics of earliest people of SW Amazonia and 2) the role these early Holocene populations played in the domestication of Neotropical plants. Genetic studies suggest that SW Amazonia, and in particular the Llanos de Moxos in Bolivia, is a region where important Amazonian crops were domesticated, including manioc, peanut, peach palm, jack bean and two varieties of chili pepper. However, genetic evidence has not been substantiated by archaeology as yet, due to the virtual absence of early sites in the region. The applicant\u2019s recent discovery of early Holocene shell-middens in the area and the application of state-of-the-art multi-proxy techniques offer a unique opportunity to provide archaeological evidence for plant exploitation trajectories. Six early sites, and their local environments, are going to be studied for the first time through a focus on socio-ecological interactions and plant management strategies. The proposal is a fundamental step in the applicant\u2019s career as he will be able to dramatically improve his technical skills in several archaeological techniques (phytoliths, starch, micromorphology, shell middens excavation). The research will also enhance the candidate's capabilities to integrate palaeoecological and archaeological evidence, a decisive move to promote his scientific leadership and career development.", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["703045"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITAT WIEN"], "EU_Contribution": ["EUR 178 156,80"], "Project_Title": ["Transnational nationalism. Far-Right Nationalist Groups in East Central Europe in the 20th and 21st centuries"], "Total_Cost": ["EUR 178 156,80"], "Country": ["Austria"], "Project_ACR": ["Transnat_farright"], "Technology_Description": "The project will study networks of youth far-right nationalist organizations in East Central Europe, paying particular attention to the developments in Austria, Croatia, Hungary, and Poland. Using historical and anthropological methods, the study explores the transnational dimension of nationalist organizations: the networking of ideologies and tactics. It entails a combination of archival research, interviews, and participant observation during nationalist gatherings. In proposing a historical-ethnographic study of youth far-right nationalist groups, the project aims to fill the gap in existing scholarship, resulting from the lack of interdisciplinary dialogue, negligence of a historical dimension, and macro-perspective predominance. Inspired by the transnational history approach, it foregrounds the complex \u2013 synchronic and diachronic - interactions between European nationalisms and studies agents of those exchanges, examining nationalist activists\u2019 motivations and experiences. A combination of anthropological in-depth analysis and historical approach offers an original perspective by drawing parallels between nationalist activities against a multinational federative system, the Austro-Hungarian Empire, and the EU. It provides a critical tool for challenging unidirectional models of modernity and nationalism and for reflecting on the challenges to the European integration.", "To": ["2017-09-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["656377"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["TECHNISCHE UNIVERSITEIT DELFT", "ALBERT-LUDWIGS-UNIVERSITAET FREIBURG", "CHALMERS TEKNISKA HOEGSKOLA AB", "KATHOLIEKE UNIVERSITEIT LEUVEN", "TECHNISCHE UNIVERSITAET MUENCHEN", "UNIVERSITY OF LIMERICK", "AMPYX POWER BV", "SKYSAILS GMBH", "XSENS TECHNOLOGIES B.V.", "ENERKITE GMBH"], "EU_Contribution": ["EUR 2 999 014,68"], "Project_Title": ["Airborne Wind Energy System Modelling, Control and Optimisation"], "Total_Cost": ["EUR 2 999 014,68"], "Country": ["Netherlands", "Germany", "Sweden", "Belgium", "Germany", "Ireland", "Netherlands", "Germany", "Netherlands", "Germany"], "Project_ACR": ["AWESCO"], "Technology_Description": "The height of conventional wind turbines is limited by the enormous stresses on the structure. The idea of the Airborne Wind Energy (AWE) is to replace the most efficient part of a conventional wind turbine, the tip of the turbine blade, with a fast flying high efficiency kite, and to replace the rest of the structure by a tether which anchors the kite to the ground. Power is generated either by periodically pulling a ground based generator via a winch, or by small wind turbines mounted on the kite that exploit its fast cross wind motion. While the concept is highly promising, major academic and industrial research is still needed to achieve the performance required for industrial deployment. This can best be done by innovative junior researchers in a closely cooperating consortium of academic and industrial partners.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["642682"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["KUNGLIGA TEKNISKA HOEGSKOLAN"], "EU_Contribution": ["EUR 185 857,20"], "Project_Title": ["Green and robust approaches towards dual-purpose dendritic adhesives: Novel minimally invasive methodologies for bone fracture fixation applications"], "Total_Cost": ["EUR 185 857,20"], "Country": ["Sweden"], "Project_ACR": ["DendroBAP"], "Technology_Description": "A vast number of human bone fractures rely on screw-fixated metal implants. While being effective, their rigid design, combined with open surgical conditions and general anesthesiology, make them poor candidates for thin or fragile bones, such as those that might be found in the elderly population. The proposal is intended to identify a minimally invasive surgical concept, based on novel bone adhesives (glues) for treatment of complicated bone fractures, under local anesthesia. This will be accomplished by developing a library comprised of a dendritic scaffold, a cross-linker and a fibre component. Upon mixing, the dendritic component is programmed to efficiently adhere to wet bone surfaces and on-demand react with the cross-linker to form a bone adhesive patch (BAP). The fibre component is embedded to produce BAPs covering a range of load bearing properties.", "To": ["2017-07-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-08-01"], "Project_ID": ["655649"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Direct and indirect effects of Climate Change on biotic communities and exotic Pathogens in mixed Mediterranean forests"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["CCPaMe"], "Technology_Description": "Global change is a complex phenomenon that involves several factors such as climate change, the alteration of the nitrogen cycle, biological invasions or changes in land use. Although each of these factors has been individually studied in detail in the last years, it is still poorly known how they could interact to affect biotic communities and the ecosystem processes that they control. The general objective of this proposal is to advance in the understanding of the direct and indirect effects of climate change on biotic communities and invasive pathogens interactions in forest systems. This interaction has been largely ignored so far, but its consideration is crucial to understand how abiotic and biotic stress factors together determine forest health and stability. Specifically, CCPaMe aims to: 1) Determine the direct effects of climate change on the exotic pathogen Phytophthora cinnamomi. It will be identified potential non-additive effects of rainfall exclusion and warming on its abundance and infected capacity by field and growth chamber experiments. 2) Determine the indirect effects of climate change on soil microorganisms and P. cinnamomi ecology. It will be determined the effects of climate change on the hosts susceptibility to P. cinnamomi and on the abundance, diversity and composition of soil organisms community (bacteria, fungi, archaea and actinomycete) and their implications for P. cinnamomi functionality: modification of its infective capacity and the alteration of pathogen interactions with other soil microbes. CCPaMe results will provide key insights to address current challenges regarding climate change effects and exotic pathogen control on forest systems and the conservation and protection of forest resources. Moreover, they will allow an improvement of our predictive capacity of the socio-economic consequences of future P. cinnamomi outbreaks, serving as a guide for the design of up-to-date management and mitigation policies.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-01-01"], "Project_ID": ["706055"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITY OF GLASGOW"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Understanding the light-fastness of heritage Turkey Red textiles through modern dye chemistry and historical dyeing technology to inform sustainable display and access"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["LightFasTR"], "Technology_Description": "LightFasTR seeks to increase physical and creative access to Europe\u2019s most profitable globalised textile of the 19th c. Industrial Revolution - Turkey red (TR) printed cotton. TR was famed for colourful bold patterns on a characteristic bright red background. Many 19th c. TR printed cottons survive within the pages of pattern books as well-preserved, vibrant and creative storyboards of forgotten global trade and cultural connections. Museums and archives want to exhibit these collections and increase access, but need to preserve the colours, especially the characteristic red. The 19th c. TR makers\u2019 claim of excellent light-fastness for the red dye is unproven, raising uncertainty about suitable light levels and exposure times for historical TR textile collections. LightFasTR unites the materials and processes of making 19th c. TR with modern dye chemistry and heritage textile conservation science to provide essential guidance for museums and archives. ", "To": ["2019-03-19, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-03-20"], "Project_ID": ["708740"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITY OF KENT"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Evolution of the Ape Forelimb: Evidence from Internal Bone Structure"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["MOSAIC"], "Technology_Description": "\"Understanding the locomotor behaviour of our Miocene ape ancestors is critical to reconstructing the evolution of walking on two feet, or bipedalism. The Miocene (20-5 million years ago (Ma)) epoch is crucial because it is during this period that the morphological features of living great apes, including humans, were defined. In this respect, Miocene apes show unique morphological combinations that are unlike any living primate, known as \"mosaic morphologies\", which include derived (ape-like) and primitive (generalised) features more suitable to provide a model from which bipedal fossil humans (hominins) \u2013 our direct ancestors \u2013 might have evolved. This project uses novel 3D methods (microCT scans and imaging sotfware) to conduct the first holistic analysis of the internal structure of Miocene ape forelimb bones. Bone remodels throughout life in response to load; variation in internal structure thus correlates with forelimb use and offers a more direct window into behaviour than external morphology alone. The bony joints of the forelimb on an array of extant Primate species, including apes and monkeys, will be analysed, shedding new light on Miocene ape locomotion, the evolution of living apes and the emergence of human bipedalism.\"", "To": ["2018-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["703608"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["BEN-GURION UNIVERSITY OF THE NEGEV", "BEN-GURION UNIVERSITY OF THE NEGEV"], "EU_Contribution": ["EUR 1 625 000"], "Project_Title": ["Quantitative Nanoscale Visualization of Macromolecular Complexes in Live Cells using Genetic Code Expansion and High-Resolution Imaging"], "Total_Cost": ["EUR 1 625 000"], "Country": ["Israel", "Israel"], "Project_ACR": ["VisuLive"], "Technology_Description": "High-resolution fluorescence imaging, including super-resolution microscopy and high-speed live cell imaging, are used to obtain quantitative information on the structural organization and kinetics of cellular processes. The contribution of these high-resolution techniques to cell biology was recently demonstrated for dynamin- and ESCRT-driven membrane fission in cells. While they advance our knowledge on membrane fission these techniques do not provide the quantitative information needed to formulate a mechanical understanding of membrane fission in a physiological context, a shortcoming that stresses the need to increase the spatiotemporal resolution and improve the live cell capabilities of these techniques. Substituting the bulky fluorescent protein tags (such as GFP) currently used in live-cell applications with much smaller fluorescent dyes that possess superior photophysical characteristics will markedly improve these advanced imaging techniques. Genetic code expansion and bioorthogonal labeling offer, for the first time, a non-invasive way to specifically attach such fluorescent dyes to proteins in live cells. I, therefore, propose to develop an innovative approach to label cellular proteins with fluorescent dyes via genetic code expansion for quantitative high-resolution live cell imaging of cellular protein complexes. By applying this approach to three distinguished high-resolution methodologies and by visualizing membrane fission in distinct cellular processes in live cells at milliseconds rate and at nanoscale resolution, we aim to decipher the mechanistic principles of membrane fission in cells. As numerous cellular processes rely on membrane fission for their function, such an understanding will have a broad impact on cell biology. The implications of this study reach beyond the scope of membrane fission by offering a new approach to study cellular processes at close-to-real conditions in live cells and at nanoscale resolution.", "To": ["2020-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-04-01"], "Project_ID": ["639313"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["BEN-GURION UNIVERSITY OF THE NEGEV", "BEN-GURION UNIVERSITY OF THE NEGEV"], "EU_Contribution": ["EUR 1 303 750"], "Project_Title": ["Combinatorial Aspects of Computational Geometry"], "Total_Cost": ["EUR 1 303 750"], "Country": ["Israel", "Israel"], "Project_ACR": ["CombiCompGeom"], "Technology_Description": "The project focuses on the interface between computational and combinatorial geometry. ", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["678765"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["UNIVERSIDAD POMPEU FABRA", "UNIVERSIDAD POMPEU FABRA"], "EU_Contribution": ["EUR 1 308 676"], "Project_Title": ["Debt and Persistence of Financial Shocks"], "Total_Cost": ["EUR 1 308 676"], "Country": ["Spain", "Spain"], "Project_ACR": ["PERSISTDEBT"], "Technology_Description": "In 2007 the US and Europe were overwhelmed by a banking crisis, which was followed by a severe economic recession. Historical studies show that financial crises are followed by periods of substantially stronger contraction of aggregate output and employment than non-financial recessions. Those studies also point out that the best predictor of financial crises is an ex-ante strong credit boom which, after the beginning of the crisis, followed by negative overall credit growth. Lastly, financial crises take a long time until recovering the pre-crisis levels. ", "To": ["2020-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-07-01"], "Project_ID": ["648398"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["UNIVERSIDAD POMPEU FABRA", "UNIVERSIDAD POMPEU FABRA"], "EU_Contribution": ["EUR 1 699 664"], "Project_Title": ["HISTORICAL ROOTS OF CONFLICT AND DEVELOPMENT: FROM PREHISTORY TO THE COLONIZATION EXPERIENCE"], "Total_Cost": ["EUR 1 699 664"], "Country": ["Spain", "Spain"], "Project_ACR": ["HISTROOTS"], "Technology_Description": "I plan to study the effect of history on conflict and economic development with two historical microscopes.", "To": ["2020-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-05-01"], "Project_ID": ["647514"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["STOCKHOLMS UNIVERSITET", "STOCKHOLMS UNIVERSITET"], "EU_Contribution": ["EUR 1 969 599"], "Project_Title": ["Towards middle-range theories of the co-evolutionary dynamics of multi-level social-ecological systems"], "Total_Cost": ["EUR 1 969 599"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["MUSES"], "Technology_Description": "Humans have the capacity to change the biosphere from local to global scales while at the same time fundamentally depending on a functioning biosphere for their well-being. Moreover human societies are increasingly affected by global change and adapting to it in multiple ways. These interdependencies give rise to non-linear, cross-scale dynamics that pose significant challenges for analysis and governance of social-ecological systems (SES). In view of the need for societal transformations towards sustainability is the identification of mechanisms of change in SES an urgent and cutting-edge research frontier. This project aims to develop new methodologies and middle-range theories of the dynamics of SES. It will take the nature of SES as complex adaptive systems into account by developing a mechanism-based understanding of change in SES as it arises from micro-level interactions within complex networks of actors and ecosystems. Particular emphasis will be put on emergent and top-down cross-scale interactions. ", "To": ["2022-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-02-01"], "Project_ID": ["682472"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["UNIVERSIDAD POMPEU FABRA", "UNIVERSIDAD POMPEU FABRA"], "EU_Contribution": ["EUR 1 170 625"], "Project_Title": ["Social Media, Political Participation, and Accountability"], "Total_Cost": ["EUR 1 170 625"], "Country": ["Spain", "Spain"], "Project_ACR": ["SocialMedia"], "Technology_Description": "The goal of the project is to examine how advances in information technologies affect public policies. In particular, it will empirically investigate the causal effect of social media on political participation. The first part of the project will examine the effect of social media penetration on participation in political protest activities, as well as the mechanisms that drive these effects, using a specific example of protests activities in Russia in 2011-2012. We will exploit idiosyncratic variation in the early penetration of social media across cities to identify causal effect of social media penetration on participation in protest activities. We will also exploit the effects of early penetration on the distribution of users across competing online social networks to examine the role of coordination as a specific mechanism behind the effect. The second part of the project will use content analysis of the messages in social media and detailed information on the network structure and its evolution over time to study (1) the effect of network structure on the diffusion of information and subsequent actions; (2) the effect of offline events on network formation. Exogenous shock in the form of unexpected wave of protest activities will be used to identify the effects of interest. Smaller parts of the project will use survey experiments and cross-country comparison of the content of traditional and social media to provide additional evidence on the mechanisms behind the effects of social media. The project will be mainly empirical, but it will rely heavily on the theoretical advances in the fields of political economy and network analysis.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["638221"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["UNIVERSIDAD POMPEU FABRA", "UNIVERSIDAD POMPEU FABRA"], "EU_Contribution": ["EUR 1 876 846"], "Project_Title": ["Post-Cellular Wireless Networks"], "Total_Cost": ["EUR 1 876 846"], "Country": ["Spain", "Spain"], "Project_ACR": ["POSTCELL"], "Technology_Description": "POSTCELL aims at laying the foundation for future generations of wireless networks as they move past the reigning cell-centric paradigm and into the post-cellular era. This entails the definition of a new architecture for such networks and the characterization of the ensuing performance. For the future of wireless communications, the implications would be far-reaching.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["694974"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["STOCKHOLMS UNIVERSITET", "STOCKHOLMS UNIVERSITET"], "EU_Contribution": ["EUR 2 499 756"], "Project_Title": ["Cryosphere-Carbon on Top of the Earth (CC-Top):Decreasing Uncertainties of Thawing Permafrost and Collapsing Methane Hydrates in the Arctic"], "Total_Cost": ["EUR 2 499 756"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["CC-TOP"], "Technology_Description": "The enormous quantities of frozen carbon in the Arctic, held in shallow soils and sediments, act as \u201ccapacitors\u201d of the global carbon system. Thawing permafrost (PF) and collapsing methane hydrates are top candidates to cause a net transfer of carbon from land/ocean to the atmosphere this century, yet uncertainties abound. ", "To": ["2021-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-11-01"], "Project_ID": ["695331"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["HASKOLI ISLANDS", "STOCKHOLMS UNIVERSITET", "UNIVERSITE CLERMONT AUVERGNE", "UNIVERSITE BLAISE PASCAL CLERMONT-FERRAND II"], "EU_Contribution": ["EUR 3 182 721,12"], "Project_Title": ["Adaptation to a New Economic Reality"], "Total_Cost": ["EUR 3 182 721,12"], "Country": ["Iceland", "Sweden", "France", "France"], "Project_ACR": ["AdaptEconII"], "Technology_Description": "The present economic model of permanent growth is unstable and leads to cycles of growth, peaks and crashes. We propose to contribute to developing new economic thinking based on knowledge of global resources availability. The Adaptation to a New Economic Reality (AdaptEconII) project is divided into three parts: 1. Sustainable resource management; 2. Integrated economic systems assessment; and 3. Integrating society and economics. These components will be combined to form an overarching economic model built on socio-environmental-technical (SET) system analysis of causal links and feedback structures and system dynamics. A simple prototype of such a model (WORLD) has already been built by the applicants and tested on historical data. Twelve Early Stage Researchers (ESRs) will be trained to obtain European Joint Doctorates at three universities: University of Iceland (Reykjavik, Iceland), Stockholm University (Sweden) and Universite Blaise Pascal, Clermont-Ferrand (France). The ESRs will have secondments in research institutes/NGOs/SMEs in Germany (GWS and Wuppertal Institute), UK (New Economics Foundation and Schumacher Institute) and Sweden (Swedish National Defense College). All of the ESRs will have a career plan and be trained in system analysis and system dynamics in addition to conventional and biophysical economic paradigms. They will be presented with aspects of resource availability, links between resources and wealth, the rise of new and/or rediscovered values and realization of our interdependent world, new development paradigms, political and industrial ecology, as well as science for sustainable society and transferable skills. AdaptEconII will train ESRs in new economic thinking and the goal is for them be at the forefront of innovative economic thinking in the EU and the world.", "To": ["2019-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-EJD - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-EJD)"], "Funding_scheme": ["MSCA-ITN-EJD - European Joint Doctorates"], "Coordinated_in": ["Iceland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-12-01"], "Project_ID": ["675153"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["BEN-GURION UNIVERSITY OF THE NEGEV", "BEN-GURION UNIVERSITY OF THE NEGEV"], "EU_Contribution": ["EUR 1 499 375"], "Project_Title": ["Unravelling the role of lysine acetylation in the regulation of glycolysis in cancer cells through the development of synthetic biology-based tools"], "Total_Cost": ["EUR 1 499 375"], "Country": ["Israel", "Israel"], "Project_ACR": ["AcetyLys"], "Technology_Description": "Synthetic biology is an emerging discipline that offers powerful tools to control and manipulate fundamental processes in living matter. We propose to develop and apply such tools to modify the genetic code of cultured mammalian cells and bacteria with the aim to study the role of lysine acetylation in the regulation of metabolism and in cancer development. Thousands of lysine acetylation sites were recently discovered on non-histone proteins, suggesting that acetylation is a widespread and evolutionarily conserved post translational modification, similar in scope to phosphorylation and ubiquitination. Specifically, it has been found that most of the enzymes of metabolic processes\u2014including glycolysis\u2014are acetylated, implying that acetylation is key regulator of cellular metabolism in general and in glycolysis in particular. The regulation of metabolic pathways is of particular importance to cancer research, as misregulation of metabolic pathways, especially upregulation of glycolysis, is common to most transformed cells and is now considered a new hallmark of cancer. These data raise an immediate question: what is the role of acetylation in the regulation of glycolysis and in the metabolic reprogramming of cancer cells? While current methods rely on mutational analyses, we will genetically encode the incorporation of acetylated lysine and directly measure the functional role of each acetylation site in cancerous and non-cancerous cell lines. Using this methodology, we will study the structural and functional implications of all the acetylation sites in glycolytic enzymes. We will also decipher the mechanism by which acetylation is regulated by deacetylases and answer a long standing question \u2013 how 18 deacetylases recognise their substrates among thousands of acetylated proteins? The developed methodologies can be applied to a wide range of protein families known to be acetylated, thereby making this study relevant to diverse research fields.", "To": ["2021-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-07-01"], "Project_ID": ["678461"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["HELMHOLTZ ZENTRUM POTSDAM DEUTSCHESGEOFORSCHUNGSZENTRUM GFZ"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Silica and alumina nanophases \u2013 the building blocks for the ground under our feet."], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["NanoSiAl"], "Technology_Description": "Alumina and silica nanophases play a crucial role in rock weathering and their formation and destruction controls Earth\u2019s response to global climate change. The presence of various products of aqueous weathering of aluminosilicates points to a complex activity of water, and is considered as the geological indication for the occurrence of life-habitable conditions. In this regard, a more complete picture of the water-alumina-silica interactions would allow for better specifying the molecular-level conditions for early life. Upon weathering the original Al- and Si-containing phases are dissolved at the solid-water interface, undergo hydrolysis and condensation reactions and form new colloidal nanoparticles. However, quantitative and mechanistic understanding of the underlying processes that lead to the formation and types of Al and Si phases is still lacking, due to the insufficient in situ methodology providing structural information about the colloidal species in solution.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations"], "From": ["2017-05-01"], "Project_ID": ["703015"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSITAT POLITECNICA DE CATALUNYA", "UNIVERSITY OF YORK", "TECHNISCHE UNIVERSITAET KAISERSLAUTERN", "NEC EUROPE LTD", "EDUCATIONAL OTE AE", "IQUADRAT INFORMATICA SL", "FASMETRICS YPIRESIES KAI PROIONTA ILEKTROMAGNITIKON PEDION ANONYMI ETAIREIA"], "EU_Contribution": ["EUR 3 545 458,56"], "Project_Title": ["Application-aware User-centric Programmable Architectures for 5G Multi-tenant Networks"], "Total_Cost": ["EUR 3 545 458,56"], "Country": ["France", "Spain", "United Kingdom", "Germany", "United Kingdom", "Greece", "Spain", "Greece"], "Project_ACR": ["5G-AURA"], "Technology_Description": "The vision of future 5G networks encompasses a heterogeneous communication landscape in which existing Radio Access Technologies (RATs) will be integrated with evolving wireless technologies and systems, software-design network architectures and cloud-enabled services. Effectively harnessing the potential of all these innovative and heterogeneous features and providing a programmable multi-tenant network architectural framework will be the key to the success of 5G, and will be the main objective of the 5G-AURA project. Instead of focusing separately on the optimization of the diverse technological and architectural components, our efforts will be concentrated on providing a unifying framework that will sustain the coexistence and coordination of networking, software and cloud technologies, ensure network programmability and efficient resource orchestration, minimize control and signalling overhead, support multi-tenancy and scalability, and promote the development of new business models for emerging services. To efficiently achieve these objectives, 5G-AURA has identified 12 specific research challenges which have been mapped to 14 individual projects that will be carried out by 14 recruited ESRs. The project\u2019s consortium, formed by four academic institutions and four industrial partners, has the necessary expertise and available infrastructures to form a high quality training network across multiple disciplines, sectors and countries. Considering that 5G is currently in an early development state and there are multiple open issues on 5G protocols, network architectures and technologies and standardization efforts, the timing of 5G-AURA is perfect, and the project has a strong potential to have significant impact on academia and industry and enhance the European innovation capacity in terms of technical contributions, intersectoral training of scientists and professional and novel business opportunities.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-10-01"], "Project_ID": ["675806"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["STOCKHOLMS UNIVERSITET", "STOCKHOLMS UNIVERSITET"], "EU_Contribution": ["EUR 1 104 812"], "Project_Title": ["Social and Political Economics: Theory and Evidence"], "Total_Cost": ["EUR 1 104 812"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["ECOSOCPOL"], "Technology_Description": "In this project, I will study how individual and social motives interact to drive individual decisions, a question that has fallen between the cracks of different social-science approaches. I will use a common theoretical framework to approach an important, but badly understood, general question: do social motives reinforce or weaken the effect of changes in individual motives? By modifying this common framework to different applications, I will consider its predictions empirically in different large data sets with individual-level information. The planned applications include four subprojects in the social, political, and economic spheres: (i) decisions in China on the ethnicity of children in interethnic marriages and matching into such marriages, (ii) decisions on tax evasion in the U.K. and Sweden, (iii) decisions to give political campaign contributions in the U.S., and (iv) decisions about fertility in Sweden. I may also spell out the common lessons from the results on the interaction between individual and social motives in monograph format intended for a broader audience.", "To": ["2021-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-11-01"], "Project_ID": ["693402"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["UNIVERSITY OF KENT", "UNIVERSITY OF KENT"], "EU_Contribution": ["EUR 1 488 028"], "Project_Title": ["Tracking the cognitive basis of social communication across the life-span"], "Total_Cost": ["EUR 1 488 028"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["CogSoCoAGE"], "Technology_Description": "A vital part of successful everyday social interaction is the ability to infer information about others (e.g. their emotions, visual perspective, and language). Development of these social skills (termed Theory of Mind, ToM) has been linked to improvements in more general cognitive skills, called Executive Functions (EF). However, to date very little is known of how this link varies with advancing age, and no model exists to explain the relationship. Thus, the key aim of the proposed research is to systematically explore the cognitive basis of social communication and how this changes across the life-span. The research will address three complementary objectives: (1) to what degree can variations in ToM ability across the life-span be accounted for by changes in EF skills, (2) how do ToM ability and EF skill change over time in different age groups (using longitudinal methods, i.e. test-retest of the same participants), and (3) can ToM ability be enhanced through training specific EF skills, and how do these training effects differ across the life-span. Contrary to traditional studies of social communication, I will employ an interdisciplinary approach that links theory and practice from cognitive, social, developmental, and clinical (neuro)psychology to study the relationship between ToM and EF across a broad and dynamic age range (10 to 80+ yrs old). I will use cutting-edge combinations of techniques (eye-tracking and EEG) and paradigms, alongside sophisticated statistical methods to track the timecourse of social understanding, and model how it relates to EF and more general cognitive/social skills (eg. IQ, language) within and between individuals. This research will open up new horizons in ToM research by developing an intervention programme to enhance the quality of social communication in older adults (thus improving their mental health and well-being), which has the potential to be applied in other individuals with social communication deficits (eg. autism).", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["636458"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["BEN-GURION UNIVERSITY OF THE NEGEV", "BEN-GURION UNIVERSITY OF THE NEGEV"], "EU_Contribution": ["EUR 1 499 000"], "Project_Title": ["The Plasmidome: a Driving Force of Rumen Microbial Evolution from Birth to Adulthood"], "Total_Cost": ["EUR 1 499 000"], "Country": ["Israel", "Israel"], "Project_ACR": ["RuMicroPlas"], "Technology_Description": "Plasmids are known to be major contributors to lateral gene transfer in bacterial genomes; however, their comprehensive evolutionary role within bacterial communities is poorly understood. Recently we have developed cutting edge abilities to access a plasmid population (plasmidome) of a given microbial community, and applied them to rumen microbial communities. These abilities are an element long-needed for the study of microbial lateral gene transfer and evolution. Ruminants house a highly complex microbial community in the rumen compartment of their digestive tract, with which they have evolved into an obligatory co-dependence. Its confined nature provides a perfect system for the study of evolutionary dynamics within microbial communities.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["640384"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["KUNGLIGA TEKNISKA HOEGSKOLAN"], "EU_Contribution": ["EUR 173 857,20"], "Project_Title": ["Nature-inspired control of turbulent flows"], "Total_Cost": ["EUR 173 857,20"], "Country": ["Sweden"], "Project_ACR": ["NiCoFlow"], "Technology_Description": "Many aspects of the animal flight still remain unexplored, despite the enormous possibilities they offer to improve the current aerospace technology. One such aspect that received least attention of the scientists is the following: the wing surfaces of the flying animals are coated with hairs, feathers and other filamentous structures. These self-adaptive hairy layers strongly influence the flow field characteristics, and it has been reported that such coatings may be used to control the laminar-turbulent transition as well as turbulence in order to achieve energy efficient flight. The objectives of the NiCoFlow project are: (1) to devise the essential mathematical and computational framework to study the flow around objects with surface-mounted self-adaptive hairs, and (2) to elucidate the fundamental fluid dynamic mechanisms through which the surface coatings can enable new flow control strategies. In this work, a homogenized poro-elastic continuum models will be used to describe the flow through the hairy layers. Moreover, a computational approach to simulate two-way coupling between such homogenized continuum models and the surrounding fluid flow will be developed.. This approach will be thoroughly validated by simulating fluid flow over a flat plate attached with surface-mounted flexible hairs and comparing the numerical results against existing experimental data. The validated model will be used to perform direct numerical simulations of transitional and turbulent flows to reveal the detailed flow characteristics, and shed light on how these self-adaptive hairy features may delay the transition to turbulence and reduce the turbulent skin-friction. A potential passive control technique, relying on these nature-inspired hairy coatings, will have a large industrial impact, including applications in aeronautics, energy harvesting and the transport sector.", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["708281"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITY OF YORK", "STOCKHOLMS UNIVERSITET", "KOBENHAVNS UNIVERSITET", "RIJKSUNIVERSITEIT GRONINGEN"], "EU_Contribution": ["EUR 4 074 239,16"], "Project_Title": ["Archaeology on the Edge: Northern Europe and the Circumpolar World"], "Total_Cost": ["EUR 4 074 239,16"], "Country": ["United Kingdom", "Sweden", "Denmark", "Netherlands"], "Project_ACR": ["ArchSci2020"], "Technology_Description": "ArchSci2020 will provide structured state-of-the-art doctoral training to the next generation of archaeologists and biomolecular scientists forging a new generation of biomolecular archaeologists. Few other academic disciplines have been so transformed in the last decade as Archaeology. ArchSci2020 meet the need of a new generation of researchers. International, intersectoral and interdisciplinary training will equip its early-stage researchers (ESRs) with specific research-related and transferable skills, in order to provide enhanced career prospects across academia, industry and the third sector. The proposed ArchSci2020 network will bring together four leading research clusters each with complementary expertise to deliver an integrated, flexible training package that will provide a sound basis for academic independence and preparation for vocations in the archaeology, heritage and beyond. ArchSci2020 will combine (i) a common purpose, (ii) an unconditional commitment to the student experience, (iii) a pro-active stance towards international, inter-institutional research support and interdisciplinary study, (iv) a simple but effective management structure provided by a Management Team, Supervisory Committee and the Work Package leaders, (v) and an established academic infrastructure and reputation.", "To": ["2020-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-EJD - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-EJD)"], "Funding_scheme": ["MSCA-ITN-EJD - European Joint Doctorates"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-04-01"], "Project_ID": ["676154"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["UNIVERSIDAD POMPEU FABRA", "UNIVERSIDAD POMPEU FABRA"], "EU_Contribution": ["EUR 282 874,96"], "Project_Title": ["Support to the Vice-Presidents of the ERC Scientific Council 2016"], "Total_Cost": ["EUR 282 874,96"], "Country": ["Spain", "Spain"], "Project_ACR": ["ERCSC-VPRES-SUP2016"], "Technology_Description": "Support to the Vice-Presidents of the ERC Scientific Council 2016", "To": ["2016-12-31, closed project"], "Meta": [""], "Topic_s": ["ERC - European Research Council"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["721182"], "Call_for_Proposal": ["H2020-Adhoc-2014-20"]}, -{"Partners": ["KUNGLIGA TEKNISKA HOEGSKOLAN", "IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE", "UNIVERSITY OF SOUTHAMPTON", "THE UNIVERSITY OF EDINBURGH", "UNIVERSITAET STUTTGART", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "MCLAREN RACING LIMITED", "AUTOMOTIVE SIMULATION CENTER STUTTGART EV"], "EU_Contribution": ["EUR 3 312 235"], "Project_Title": ["Enabling Exascale Fluid Dynamics Simulations"], "Total_Cost": ["EUR 3 312 235"], "Country": ["Sweden", "United Kingdom", "United Kingdom", "United Kingdom", "Germany", "Switzerland", "United Kingdom", "Germany"], "Project_ACR": ["ExaFLOW"], "Technology_Description": "We are surrounded by moving fluids (gases and liquids), be it during breathing or the blood flowing in arteries; the flow around cars, ships, and airplanes; the changes in cloud formations or the plankton transport in oceans; even the formation of stars and galaxies are closely modeled as phenomena in fluid dynamics. Fluid Dynamics (FD) simulations provide a powerful tool for the analysis of such fluid flows and are an essential element of many industrial and academic problems.", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["FETHPC-1-2014 - HPC Core Technologies, Programming Environments and Algorithms for Extreme Parallelism and Extreme Data Applications"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations"], "From": ["2015-10-01"], "Project_ID": ["671571"], "Call_for_Proposal": ["H2020-FETHPC-2014"]}, -{"Partners": ["UNIVERSITAET INNSBRUCK", "FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG", "THE QUEEN'S UNIVERSITY OF BELFAST", "KUNGLIGA TEKNISKA HOEGSKOLAN", "NUMERICAL MECHANICS APPLICATIONS INTERNATIONAL SA", "IBM IRELAND LIMITED"], "EU_Contribution": ["EUR 3 366 196"], "Project_Title": ["An Exascale Programming, Multi-objective Optimisation and Resilience Management Environment Based on Nested Recursive Parallelism"], "Total_Cost": ["EUR 3 366 196"], "Country": ["Austria", "Germany", "United Kingdom", "Sweden", "Belgium", "Ireland"], "Project_ACR": ["ALLScale"], "Technology_Description": "Extreme scale HPC systems impose significant challenges for developers aiming at obtaining applications efficiently utilising all available resources. In particular, the development of such applications is accompanied by the complex and labour-intensive task of managing parallel control flows, data dependencies and underlying hardware resources \u2013 each of these obligations constituting challenging problems on its own. The AllScale environment, the focus of this project, will provide a novel, sophisticated approach enabling the decoupling of the specification of parallelism from the associated management activities during program execution. Its foundation is a parallel programming model based on nested recursive parallelism, opening up the potential for a variety of compiler and runtime system based techniques adding to the capabilities of resulting applications. These include the (i) automated porting of application from small- to extreme scale architectures, (ii) the flexible tuning of the program execution to satisfy trade-offs among multiple objectives including execution time, energy and resource usage, (iii) the management of hardware resources and associated parameters (e.g. clock speed), (iv) the integration of resilience management measures to compensate for isolated hardware failures and (v) the possibility of online performance monitoring and analysis. All these services will be provided in an application independent, reusable fashion by a combination of sophisticated, modular, and customizable compiler and runtime system based solutions.", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["FETHPC-1-2014 - HPC Core Technologies, Programming Environments and Algorithms for Extreme Parallelism and Extreme Data Applications"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-10-01"], "Project_ID": ["671603"], "Call_for_Proposal": ["H2020-FETHPC-2014"]}, -{"Partners": ["KUNGLIGA TEKNISKA HOEGSKOLAN", "KUNGLIGA TEKNISKA HOEGSKOLAN"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Minimal invasive x-ray source enabled by a novel vacuum packaging technique"], "Total_Cost": ["EUR 150 000"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["xMEMSRAY"], "Technology_Description": "In this project we aim to demonstrate and test a MEMS-based miniaturized electronic x-ray source enabled through a vacuum packaging concept developed under an ERC AdG. The source should be capable of delivering doses up to approximately 1 Gy/min at a 2 mm distance while still having a millimetre overall size. This will be achieved by combining the vacuum packaging technique with a pointed field emission array developed in another project. The goal of the project is to demonstrate key functionalities and take the technology to TRL 4 with the ambition establish collaboration with leading company in brachytherapy.", "To": ["2015-12-31, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2014 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-01-01"], "Project_ID": ["641386"], "Call_for_Proposal": ["ERC-2014-PoC"]}, -{"Partners": ["KUNGLIGA TEKNISKA HOEGSKOLAN", "KUNGLIGA TEKNISKA HOEGSKOLAN"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Inkjet Printed Ultrafast Batteries and Large Integrated Capacitors"], "Total_Cost": ["EUR 150 721,25"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["iPUBLIC"], "Technology_Description": "Energy storage has become a global concern in modern society. With his ERC Advanced grant, Prof. \u00d6stling, an expert in solid state electronics from the KTH Royal Institute of Technology in Sweden, is trying to develop emerging devices based on silicon technology but with other materials than silicon, such as graphene and its analogue MoS2. These unique materials offer opportunities to novel applications, especially those related to energy storage. Prof. \u00d6stling and his team have recently developed an efficient inkjet printing technique to reliably deposit these materials at high resolution. They have been able to directly print graphene-based supercapacitors with good performance. In the new PoC project, they will employ the inkjet printing techniques to demonstrate a novel type of energy storage devices which are expected to possess both high energy density and high power density, and establish initial commercialisation steps. Although the novel devices have complicated structure, the full-printing solution will not evidently increase the production cost. Considering the improved performance, the effective cost is actually reduced. Furthermore, the printing solution facilitates scaling up during commercialisation. These printed ultrafast batteries have great potential to meet the urgent and increasing demands from the rapid growth of portable electronic devices and electric vehicles.", "To": ["2016-05-31, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2014 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2014-12-01"], "Project_ID": ["641416"], "Call_for_Proposal": ["ERC-2014-PoC"]}, -{"Partners": ["TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY", "WEIZMANN INSTITUTE OF SCIENCE", "EUROPEAN MOLECULAR BIOLOGY LABORATORY", "IMPASARA LIMITED", "AGILENT TECHNOLOGIES LDA ISRAEL LTD", "KAROLINSKA INSTITUTET", "GENOME RESEARCH LIMITED"], "EU_Contribution": ["EUR 3 999 661"], "Project_Title": ["Massive Reverse Genomics to Decipher Gene Regulatory Grammar"], "Total_Cost": ["EUR 3 999 661"], "Country": ["Israel", "Israel", "Germany", "United Kingdom", "Israel", "Sweden", "United Kingdom"], "Project_ACR": ["MRG-GRammar"], "Technology_Description": "MRG-GRammar aims to devise an entirely new strategy for deciphering the regulatory rules of gene regulation. We will leverage Synthetic Biology with cutting-edge DNA synthesis technologies and high-throughput analysis to generate new types of biological datasets that systematically explore all possible regulatory landscapes rather than just the naturally occurring regulatory sequences.", "To": ["2018-07-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-1-2014 - FET-Open research projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2015-08-01"], "Project_ID": ["664918"], "Call_for_Proposal": ["H2020-FETOPEN-2014-2015-RIA"]}, -{"Partners": ["UNIVERSIDAD POMPEU FABRA", "UNIVERSIDAD POMPEU FABRA"], "EU_Contribution": ["EUR 811 750"], "Project_Title": ["Justice and the Family: An Analysis of the Normative Significance of Procreation and Parenthood in a Just Society"], "Total_Cost": ["EUR 811 750"], "Country": ["Spain", "Spain"], "Project_ACR": ["Family Justice"], "Technology_Description": "This project examines the normative significance of procreation and parenthood for theories of justice. Important questions of justice about the family arise once we acknowledge and keep in view that procreation and parenthood are both integral to the existence of any society (and therefore, a just society), and that they involve substantial benefits and burdens for parents, children, and society at large. Yet existing theories of justice generally neglect these questions by assuming that the principles they formulate are to regulate the main institutions of societies constituted by fully formed adult individuals whose creation and care are taken as given. The project identifies and analyses three main sets of questions about family justice: 1) Does justice require that parents and non-parents share, and share equally, the costs and benefits of having children, and how do different answers to this question bear on our theory of distributive justice? 2) What are the claims of justice that we have as children, how do they relate to those we have as adults, and who bears the correlative duties? 3) Do all contemporaries, regardless of whether they are parents or non-parents, have the same obligations of justice towards future generations, and how, if at all, are the justification and the content of those obligations affected by considerations about what parents owe their children and parents and non-parents owe to each other? Addressing these questions contributes to developing normative-theoretical framework needed to address pressing public policy concerns, and also turns out to be more central to the formulation of a complete and defensible theory of justice than political philosophers have realised to date.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["648610"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["KUNGLIGA TEKNISKA HOEGSKOLAN", "KUNGLIGA TEKNISKA HOEGSKOLAN"], "EU_Contribution": ["EUR 1 725 000"], "Project_Title": ["Long-term molecular nanoscale imaging of neuronal function"], "Total_Cost": ["EUR 1 725 000"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["MoNaLISA"], "Technology_Description": "Synaptic function is difficult to analyze in living neurons using conventional optics, since the synaptic organelles and protein clusters are small and tightly spaced. The solution to this problem can come from the field of super-resolution fluorescence microscopy, or nanoscopy. However, the current approaches to nanoscopy are still far from reaching this goal. Single molecule-based approaches (including STORM and PALM) provide high spatial resolution, but slow recording, insufficient for live imaging. Ensemble approaches (including SSIM and STED) are able to record faster, but with poorer resolution or with high, potentially toxic, laser powers. It is currently impossible to image the same neuron for hours and days, with both high spatial (~30 nm) and temporal (10-1000 Hz) resolution, and with minimal photodamage. My aim is to fill this gap, by developing, for the first time, a microscope that combines the advantages of both single molecule-based and ensemble approaches. I will base the microscope on RESOLFT, a low-photodamage ensemble approach that I have pioneered recently. I will use line patterns to speed up the recording and 2photon-switching for 3D ability. I will combine this with sensitive detection schemes that allow single-molecule detection and counting, relying on my previous expertise with PALM and GSDIM. The new set-up, termed molecular nanoscale long-term imaging with sequential acquisition (MoNaLISA), will track neuronal organelles and proteins on different time scales, spanning from milliseconds to days, with a resolution close to the molecular scale. To obtain the first proof-of-principle results, I will address several issues still open in the synaptic transmission field, relating to synaptic vesicle recycling, biogenesis and degradation. Overall, my project will introduce a novel paradigm to imaging in the life sciences, which will enable fast and quantitative nano-imaging of cells and tissues.", "To": ["2020-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-04-01"], "Project_ID": ["638314"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA", "FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA"], "EU_Contribution": ["EUR 1 608 125"], "Project_Title": ["High-frequency printed and direct-written Organic-hybrid Integrated Circuits"], "Total_Cost": ["EUR 1 608 125"], "Country": ["Italy", "Italy"], "Project_ACR": ["HEROIC"], "Technology_Description": "The HEROIC project aims at filling the gap between the currently low operation frequencies of printed, organic flexible electronics and the high-frequency regime, by demonstrating polymer-based field-effect transistors with maximum operation frequencies of 1 GHz and complementary integrated logic circuits switching in the 10-100 MHz range, fabricated by means of printing and direct-writing scalable processes in order to retain low temperature manufacturability of cost-effective large area electronics on plastic. The recent development of semiconducting polymers with mobilities in the range of 1 to 10 cm^2/Vs, and even higher in the case of aligned films, suggests that suitably downscaled printed polymer transistors with operation frequencies in the GHz regime, at least three orders of magnitude higher than current printed polymer devices, are achievable, by addressing in a holistic approach the specific challenges set in the HEROIC trans-disciplinary research programme: (i)development of scalable high resolution processes for the patterning of functional inks, where printing will be combined with direct-writing techniques such as fs-laser machining, both in an additive and subtractive approach; (ii)development of printable nanoscale hybrid dielectrics with high specific capacitance, where low-k polymer buffer materials will be combined with solution processable high-k dielectrics, such as insulating metal oxides; (iii)improvement of the control of charge injection and transport in printed polymer and hybrid semiconductors, where high-mobility 1-D and 2-D structures are included in polymer films; (iv)development of advanced printed and direct-written transistors architectures with low parasitic capacitances for high-speed operation. HEROIC will radically advance and expand the applicability of polymer-based printed electronics, thus making it suitable for next generation portable and wearable short-range wireless communicating devices with low power consumption.", "To": ["2020-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Chiara Andreoli", "Tel.: +3901071781854", "Fax: +39 010 7170817", "Research Organisations", "Chiara Andreoli", "Tel.: +3901071781854", "Fax: +39 010 7170817"], "From": ["2015-04-01"], "Project_ID": ["638059"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["KUNGLIGA TEKNISKA HOEGSKOLAN", "KUNGLIGA TEKNISKA HOEGSKOLAN"], "EU_Contribution": ["EUR 146 897"], "Project_Title": ["Industrial implementation of adaptive computational methods for turbulent flow and fluid-structure interaction"], "Total_Cost": ["EUR 146 897"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["ADAPTIVE"], "Technology_Description": "The ERC StG project UNICON (Project ID 202984) was completed in July 2013. The goal of UNICON was to develop new adaptive finite element methods for computer simulation of fluid-structure interaction, in particular for problems involving turbulent flow. Simulation of turbulent flow is an outstanding computational challenge, where the UNICON project made significant progress beyond the state of the art. The scientific results of the UNICON project include a new theoretical and methodological framework, and a computer implementation of the methods as open source software, published as part of the FEniCS project, co-founded by the PI (Hoffman) in 2003. FEniCS is today a world leading open source software for computer simulation based on differential equations, with an estimated 50 000 downloads per year, and the PI today leads the PRACE Tier-0 project FEniCS-HPC, in which algorithms and software are developed for the most powerful supercomputers in Europe. Compared to competing simulation software, free as well as commercial, UNICON computational technology has proven to exhibit unique features with respect to accuracy and efficiency. ", "To": ["2016-09-30, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2014 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-04-01"], "Project_ID": ["665630"], "Call_for_Proposal": ["ERC-2014-PoC"]}, -{"Partners": ["INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Multimodal Imaging of Disorders of Consciousness"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["MIDOC"], "Technology_Description": "The diagnosis of individuals with disorders of consciousness has fundamental implications in terms of prognosis, treatment, palliative care and even proper end-of-life decisions. Diagnosis based on behavioural assessment is difficult and it is believed that misdiagnosis occurs in a large percentage of cases (> 40%). Non-invasive functional brain imaging has recently emerged as a promising tool for the diagnosis of individuals with disorders of consciousness; however, different imaging methods allow descriptions at limited spatial and temporal resolutions, and it is unknown how these findings relate to each other, to the underlying brain anatomy, and whether they are manifestations of a single fundamental mechanism underlying the impairment of conscious awareness. ", "To": ["2018-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2016-11-01"], "Project_ID": ["702681"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["CORK INSTITUTE OF TECHNOLOGY"], "EU_Contribution": ["EUR 187 866"], "Project_Title": ["Semiconductor laser with photonic crystal reflector for energy-efficient optical links"], "Total_Cost": ["EUR 187 866"], "Country": ["Ireland"], "Project_ACR": ["SELAPHOR"], "Technology_Description": "Our information society relies to an unprecedented extent on broadband communication technologies with applications such as high-speed internet access, cloud computing, data services, multimedia broadcast systems etc. The amount of data processed by data centers continues to grow with a steep progression. We are unused to considering the energy cost of light communication, but it is huge, matching the airline industry. To meet the need for increased bandwidth, compactness, reduced power consumption and cost effectiveness, we will develop new optical sources with narrow linewidth, high-speed frequency modulation and reduced power consumption that can be utilised in modern optical links. ", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["703979"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSIDAD POMPEU FABRA"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Technology and Political Change: Nuclear Power in the Post-Soviet Union"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["TechPolChange"], "Technology_Description": "Focusing on the case of nuclear power in post-Soviet Russia and Ukraine (1990-present), this research and training project analyzes the relationship between political elites, scientific experts and the public in the context of political change and incomplete democratization. The project will move beyond existing studies and analyze the co-evolution of risky technologies and political systems in transition. To date, research on political transition in Russia and Ukraine has not sufficiently taken into account science and technology (S and T). Similarly, the analysis of S and T has been disconnected from changes in political institutions and practices. This project will consider how Ukrainian and Russian policy makers and specialists have navigated new political circumstances and forms of public engagement to advance nuclear power programs. It will study how nuclear technologies are governed, how they are received in society, and evaluate public controversies over costly and potentially risky large scale technological systems. This research has relevance for Horizon 2020 concerning reliable and clean energy, as well as the impact of technopolitical change on the European periphery on Europe's energy, security and integration. ", "To": ["2019-02-27, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-02-28"], "Project_ID": ["705577"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITA CA' FOSCARI VENEZIA"], "EU_Contribution": ["EUR 180 277,20"], "Project_Title": ["Civic community and public space in the ancient Near East. The case of Hittite Anatolia at the end of the Late Bronze Age (14th-13th centuries BCE)."], "Total_Cost": ["EUR 180 277,20"], "Country": ["Italy"], "Project_ACR": ["COMPUS"], "Technology_Description": "\"This project proposes to study public space of the ancient Near Eastern cities as a material correlate of civic communities. Civic communities acted as a significant political factor throughout the history of the ancient Near East, both as institutions (e.g., assemblies) and as informal groups (the \u201ctown's crowd\u201d). These forms of social aggregation were influential and often antagonistic alternatives to the monarchical and religious central powers. However, while the Temple and the Palace as architectonic materializations of dominant powers engaged entire generations of archaeologists, the traces left by civic communities in the urban texture of the ancient cities have received far less attention.", "To": ["2019-01-10, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-01-11"], "Project_ID": ["703187"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["KUNGLIGA TEKNISKA HOEGSKOLAN"], "EU_Contribution": ["EUR 185 857,20"], "Project_Title": ["From Landscapes to Earthscapes: Understanding Visual Cultures of Global Environmental Crisis and the Making of Global Environmental Images, 1945-present (EARTHSCAPES)"], "Total_Cost": ["EUR 185 857,20"], "Country": ["Sweden"], "Project_ACR": ["EARTHSCAPES"], "Technology_Description": "From Landscapes to Earthscapes: Understanding Visual Cultures of Global Environmental Crisis and the Making of Global Environmental Images, 1945-present (EARTHSCAPES)", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["707593"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["BEN-GURION UNIVERSITY OF THE NEGEV"], "EU_Contribution": ["EUR 182 509,20"], "Project_Title": ["Type 1 reyanodine receptor Structure and regulation by post-translational modifications and small molecules."], "Total_Cost": ["EUR 182 509,20"], "Country": ["Israel"], "Project_ACR": ["channelopathies"], "Technology_Description": "This proposal is aiming at understanding the structural basis of the type 1 ryanodine receptor (RyR1) regulation by post-translational modifications and by small molecules. RyR1 is present on the sarcoplasmic and endoplasmic reticuli of many mammalian cell types, most notably, in skeletal muscles. RyR channels are required for calcium release from intracellular stores, a process essential for excitation-contraction (EC) coupling in skeletal (RyR1) and cardiac (RyR2) muscles. They are amongst the largest ion channels, comprised of the four identical ~565 kDa channel-forming protomers. RyRs channel activity is regulated by post-translational modifications through multiple signaling pathways including adrenergic stimulation. We have obtained a 4.3 \u00c5 resolution cryo-electron microscopy (Cryo-EM) structure of RyR1 in the closed state and a 3.6 \u00c5 structure in an activated state. An atomic model was built, defining the transmembrane pore, placing all cytosolic domains as tertiary folds and unambiguously identifying small ligands including calcium, ATP, caffeine and the ryanodine in unprecedented details. In both data sets obtained, 3-D classification of particles revealed multiple distinct conformations providing a broad detailed picture of the dynamic process of RyR1 gating. Here, I aim at improving and completing the atomic model of RyR1 and at determining the structural basis for RyR1 regulation by post-translational modifications and by small molecules. I will use X-ray crystallography to determine the high-resolution structure of the full length RyR1 as well as small fragments including the transmembrane pore and drug binding sites. Cryo\u2013EM and 3-D classification will be used to identify structural changes induced by post-translational modifications and by native ligands and drugs binding. The mechanism of drugs targeting RyRs such as dantrolene and rycals can lead to structure-based design of more potent/safer drugs for malignant hyperthermia and muscular dystrophy.", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["708572"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITY OF KENT"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Restoration and Faith: practicing religion and conservation in Mexico's historic churches"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["MEXRES"], "Technology_Description": "The proposed project addresses the restoration of a colonial era Catholic church located in a peripheral indigenous community in the state of Oaxaca, Mexico. It investigates the ways in which the professionals concerned with the conservation of the church as a federally-protected historic site engage with the local religious community that has particular rights in, and relationships with, the building and objects that are to undergo repair. It raises larger political and ethical questions of how divergent ideological, aesthetic and cultural values are negotiated in contexts of religious heritage conservation. This is a social anthropology project that is grounded in a broader multidisciplinary approach that connects with art and architectural history, conservation sciences, and religious studies. The aims are to investigate: 1. the cultural, religious, and vocational ideologies and beliefs that come into conflict as actors work through restoration projects together; 2. how the material and immaterial aspects of sacred and historically valuable objects are understood by different stakeholders; and 3. how relations of power are manifested and reinforced or resisted during restoration projects. These aims will be achieved through 8 months of ethnographic research in Oaxaca with conservation experts associated with a private foundation that funds many restorations in the state, and with the local community and clergy in the municipality where the church is located. This research will be supplemented by preparatory research at the University of Kent on heritage conservation practices and will be disseminated through an academic and public engagement plan that includes a public debate, a photograph exhibition, an academic workshop, and two journal articles.", "To": ["2018-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-12-01"], "Project_ID": ["701601"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITY OF KENT"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Distributed Massive MIMO for Next Generation Wireless Communications"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["FUTURE-MOBILE"], "Technology_Description": "In view of the rapid increase in demand for mobile data services, next generation wireless communication systems will have to provide greatly increased capacity density and high data rates greater than 50Gbps. However, satisfying these requirements for increasing numbers of users and connected devices, and increasingly bandwidth, processing power and energy-hungry applications will require a transformation in the way in which current mobile and wireless networks perform. Recently, massive multiple input multiple output (MIMO) technology, where each base station (BS) is equipped with a large number of antenna elements (typically tens or even hundreds) has emerged as a key enabler to achieve a 1000 times data rate and enormous spectral and energy efficiency. In order for massive MIMO to become a reality, the proposed work aims to explore transformative methods for the design of innovative techniques in 3 key challenging areas of massive MIMO communication systems: (i) fundamental limits; (ii), (ii) transmission strategy; and (iii) caching mechanisms. The solution is achieved with small remote antenna units equipped with compact massive MIMO arrays deployed over certain coverage regions, and developing practical signalling schemes, network coordination, and management protocols.", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["709291"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSIDAD POMPEU FABRA", "UNIVERSIDAD POMPEU FABRA"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Culture Aware Music Technologies"], "Total_Cost": ["EUR 150 000"], "Country": ["Spain", "Spain"], "Project_ACR": ["CAMUT"], "Technology_Description": "The gap between the current capabilities of the music technologies used in commercial services and the needs of our culturally diverse world is still immense, e.g. in the several music traditions of culturally rich and diverse India. The existing technologies fall short of utilizing even the basic musical characteristics and hence they limit our music listening experience. The consumption practices of services and products for Indian music vary to a large extent from those of other popular music genres and they need to be addressed. An emerging market for digital music distribution in India will need music intelligence technologies that are adapted to local needs and music tastes. Hence, India is a natural venue to assess the market potential and needs for culturally adapted information and communication technologies (ICTs) for music. Culture Aware Music Technologies (CAMUT) aims at bringing closer to market, the results of new research carried out to address such a need. ", "To": ["2017-04-30, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2015 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-11-01"], "Project_ID": ["680608"], "Call_for_Proposal": ["ERC-2015-PoC"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "UNIVERSITE DE BORDEAUX", "TECHNISCHE UNIVERSITAET KAISERSLAUTERN", "RIJKSUNIVERSITEIT GRONINGEN", "KUNGLIGA TEKNISKA HOEGSKOLAN", "WEIZMANN INSTITUTE OF SCIENCE", "WAGENINGEN UNIVERSITY", "UNIVERSITE DE STRASBOURG", "Novo Nordisk A/S"], "EU_Contribution": ["EUR 2 646 333,72"], "Project_Title": ["Multi-Stimuli Responsive Molecular Systems and Materials"], "Total_Cost": ["EUR 2 646 333,72"], "Country": ["United Kingdom", "France", "Germany", "Netherlands", "Sweden", "Israel", "Netherlands", "France", "Denmark"], "Project_ACR": ["ResMoSys"], "Technology_Description": "Nanotechnology has been identified as a key enabling technology of economic growth and the value of nanomaterials in the global market is forecast to grow to \u20ac2 trillion by 2015. In order to be a market leader in this area, it is imperative that Europe invest in research where the gap between knowledge creation and successful commercialisation is bridged, and in training the next generation of highly skilled researchers in nanotechnology. This ETN will increase innovation capacity and strengthen doctoral training in nanotechnology on a European level.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["642192"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["UNIVERSIDAD POMPEU FABRA"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Bayesian Monte Carlo for Global Illumination"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["BMC Rendering"], "Technology_Description": "One of the most challenging problems in computer graphics (CG) is to synthesize physically-based realistic images given an accurate model of a virtual scene. Rendering a photo-realistic image requires solving the illumination integral which describes the light transport on a scene, and whose value is in general computed by resorting to numerical approximations such as those based on Monte Carlo (MC) methods. ", "To": ["2018-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-08-01"], "Project_ID": ["707027"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITY OF LEEDS", "LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN", "DEUTSCHES MUSEUM VON MEISTERWERKEN DER NATURWISSENSCHAFT UND TECHNIK", "KUNGLIGA TEKNISKA HOEGSKOLAN"], "EU_Contribution": ["EUR 3 144 654,72"], "Project_Title": ["Environmental Humanities for a Concerned Europe"], "Total_Cost": ["EUR 3 144 654,72"], "Country": ["United Kingdom", "Germany", "Germany", "Sweden"], "Project_ACR": ["ENHANCE"], "Technology_Description": "ENHANCE (Environmental Humanities for a Concerned Europe) will provide the first fully coordinated training programme for Environmental Humanities in Europe. It will train twelve early-stage researchers, joining three leading universities for environmental research\u2013\u2013the University of Leeds, Ludwig-Maximilians-University Munich, and the Royal Institute of Technology, Stockholm\u2013\u2013with Europe's largest science and technology museum, the Deutsches Museum, and a further five Associated Partners from the private and third sectors. ", "To": ["2019-02-28, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2015-03-01"], "Project_ID": ["642935"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Secure Quantum Communication and Computation"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SeQuCom"], "Technology_Description": "Quantum Theory is one of the greatest scientific revolutions of the twentieth century. During the last decades, it has become apparent that the tools provided by quantum mechanics can be used in many fields, such as cryptography, algorithms, game theory, and even biology. This is because quantum systems exhibit an intrinsic randomness that can be exploited in order to significantly boost computational performance, increase security of communications and in general achieve tasks that are impossible with purely classical means. On the other hand, the use of quantum technologies in future telecommunication networks, raises important questions on the security of the currently deployed protocols since quantum adversaries will be able to use quantum effects to break widely-deployed cryptosystems (e.g. RSA).", "To": ["2019-02-05, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-02-06"], "Project_ID": ["705194"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["KUNGLIGA TEKNISKA HOEGSKOLAN", "KUNGLIGA TEKNISKA HOEGSKOLAN"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Platform for Heterogeneous Integration of NEMS on ICs"], "Total_Cost": ["EUR 150 000"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["MaMs2"], "Technology_Description": "Within the ERC-M&M\u00b4s Starting Grant project (No.277879) we are exploring an innovative platform technology for wafer-level heterogeneous integration of integrated circuits (ICs) with micro/nano-electromechanical systems (MEMS/NEMS). This type of heterogeneous 3D integration technology is part of the More-than-Moore paradigm depicted in the International Technology Roadmap for Semiconductors (ITRS) and allows the combination of standard CMOS-based integrated circuits and high-performance MEMS devices to form complex and highly integrated systems that are not possible to manufacture with other micro-manufacturing approaches. First heterogeneous integration platforms for IC-integrated MEMS products have already been commercialized with great success by InvenSense (USA) and by mCube (USA) in collaboration with TSMC (Taiwan), the world\u2019s largest CMOS foundry. However, the established heterogeneous integration technologies have limitations with respect to the type of MEMS devices that can be realized and the extent to which the MEMS-ICs system component can be miniaturized. The heterogeneous integration platform developed in this ERC-M&M\u2019s+2 Proof of Concept proposal is suitable for a variety of small-sized MEMS components with large-volume markets, including infrared (IR) detector arrays, micro-mirror arrays, ultra-low power circuits based on NEM switches (a specific target application are low-power FPGAs), gyroscopes, accelerometers, microphones, etc. Thus, the heterogeneous integration platform is addressing a potential multi-billion \u20ac market. In contrast to the competing technologies, our heterogeneous integration platform is enabling the integration of ICs and MEMS/NEMS devices with extremely small device dimensions in the nm-range, very small via dimensions in the sub-1\u03bcm-range and placement accuracies of the MEMS/NEMS components on the target ICs in the nm-range.", "To": ["2016-12-31, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2015 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-07-01"], "Project_ID": ["680884"], "Call_for_Proposal": ["ERC-2015-PoC"]}, -{"Partners": ["TECHNISCHE UNIVERSITAET WIEN", "TECHNISCHE UNIVERSITAET WIEN", "KUNGLIGA TEKNISKA HOEGSKOLAN"], "EU_Contribution": ["EUR 149 625"], "Project_Title": ["Non-Volatile Magnetic Flip Flop"], "Total_Cost": ["EUR 149 625"], "Country": ["Austria", "Austria", "Sweden"], "Project_ACR": ["NOVOFLOP"], "Technology_Description": "The physical limits of CMOS scaling and the prohibitively high costs of future technology nodes, allows to foresee the end of further progress of CMOS technology in the near future and emphasizes the dire need to explore alternative technologies and computational principles.", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2015 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["692653"], "Call_for_Proposal": ["ERC-2015-PoC"]}, -{"Partners": ["UNIVERSITY OF KENT", "UNIVERSITY OF KENT"], "EU_Contribution": ["EUR 149 917"], "Project_Title": ["Add-on module for optical coherence tomography with en-face view option"], "Total_Cost": ["EUR 149 917"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["AMEFOCT"], "Technology_Description": "By the end of the 4th year of the ERC Advanced grant, the PI has set up the basis of a unique procedure to perform optical coherence tomography (OCT) that is similar in outcome to time domain interferometry but has all advantages of spectral domain interferometry in terms of speed and sensitivity. The new method of OCT, termed as Master/Slave (MS), is characterised by several advantages: direct production of an en-face OCT image, tolerance to dispersion that allows MS-OCT to achieve the theoretical limit of axial resolution and sensitivity that can be tailored for no hardware and time cost, with the axial resolution. By excellence, the Master/Slave OCT method delivers en-face views direct, allowing lower cost hardware and faster provision of en-face slicing and visualisation. An essential advantage is that of parallel processing, that makes MS-OCT, ideally suited to novel parallel optical configurations and graphic processing units (GPU). These advantages can substantially increase the speed in providing volumes of the tissue, making the new OCT method superior to all other methods on the market. The POC support will help advance the MS-OCT closer to commercialisation. Four market strategies are identified with immediate products for the first two. OCT add-on modules, equipped with MS software, for: A. OCT developers, to accelerate their research and B. OCT developers that can modify existing commercial OCT systems, by making them accomplish the MS protocol. The module to be assembled and assessed for commercialisation will also pave the way to two more strategies: C. Companies already selling OCT systems on dedicated markets, where specialised agreements will widen the market and even D. A full OCT system created by the new company, an ultimate outcome that requires investment, based on revenue acquired by selling the add-on modules.", "To": ["2017-04-30, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2015 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-11-01"], "Project_ID": ["680879"], "Call_for_Proposal": ["ERC-2015-PoC"]}, -{"Partners": ["UNIVERSIDAD POMPEU FABRA", "PHILIPS FRANCE"], "EU_Contribution": ["EUR 1 021 497,12"], "Project_Title": ["Towards a novel paradigm for cardiac function assessment from imaging"], "Total_Cost": ["EUR 1 021 497,12"], "Country": ["Spain", "France"], "Project_ACR": ["CardioFunXion"], "Technology_Description": "Cardiovascular diseases have been defined as a top priority within H2020. Although diagnostic approaches and therapies have drastically improved over the last decennia, effective, validated and auditable tools for the integrated assessment of cardiac function in clinical practice have yet to be developed. ", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-EID - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-EID)"], "Funding_scheme": ["MSCA-ITN-EID - European Industrial Doctorates"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-09-01"], "Project_ID": ["642676"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["FORSCHUNGSVERBUND BERLIN EV", "STOCKHOLMS UNIVERSITET", "THE UNIVERSITY OF BIRMINGHAM", "KUNGLIGA TEKNISKA HOEGSKOLAN", "UNIVERSITAET BAYREUTH", "IWW RHEINISCH-WESTFALISCHES INSTITUT FUER WASSER BERATUNGS-UND ENTWICKLUNGSGESELLSCHAFT MBH", "Roehampton University", "NATURALEA CONSERVACIO, SL", "CRANFIELD UNIVERSITY"], "EU_Contribution": ["EUR 3 090 951,60"], "Project_Title": ["Hyporheic Zone Processes \u2013 A training network for enhancing the understanding of complex physical, chemical and biological process interactions"], "Total_Cost": ["EUR 3 090 951,60"], "Country": ["Germany", "Sweden", "United Kingdom", "Sweden", "Germany", "Germany", "United Kingdom", "Spain", "United Kingdom"], "Project_ACR": ["HypoTRAIN"], "Technology_Description": "Hyporheic zones (HZs) are key compartments for the functioning of aquatic ecosystems. As dynamic and complex transition regions between rivers and aquifers, they are characterized by the simultaneous occurrence of multiple physical, biological and chemical processes. Turnover and degradation of nutrients and pollutants figure among the prominent ecological services the HZ provides. We are facing a significant knowledge gap in the understanding of how hyporheic processes are linked and how they impact on each other. This can be attributed to a lack of truly supra-disciplinary research and harmonized and innovative investigation methods.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2015-01-01"], "Project_ID": ["641939"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Excitonic quasiparticles in Titania"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["exciTitania"], "Technology_Description": "Although titanium dioxide (TiO2) is widely employed in fields like photovoltaics and photocatalysis, the nature of its fundamental charge transfer excitations is still unknown. A deep understanding of the excitonic properties of TiO2 is of high relevance to achieve major advances in the aforementioned fields and may lead to the fabrication of new devices with enhanced performance in energy conversion applications.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["753874"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["DET KONGELIGE DANSKE KUNSTAKADEMIS SKOLER FOR ARKITEKTUR, DESIGN OG KONSERVERING.", "UNIVERSITY COLLEGE LONDON", "UNIVERSITAET STUTTGART", "UNIVERSITAT FUR ANGEWANDTE KUNST WIEN", "KUNGLIGA TEKNISKA HOEGSKOLAN", "INSTITUT D'ARQUITECTURA AVANCADA DE CATALUNYA"], "EU_Contribution": ["EUR 3 972 691,44"], "Project_Title": ["Building Innovation in the Extended Digital Chain"], "Total_Cost": ["EUR 3 972 691,44"], "Country": ["Denmark", "United Kingdom", "Germany", "Austria", "Sweden", "Spain"], "Project_ACR": ["InnoChain"], "Technology_Description": "The InnoChain ETN network is a shared research training environment examining how advances in digital design tools challenge building culture enabling more sustainable, more informed and more materially smart design solutions. The network aims to train a new generation of interdisciplinary researchers with a strong industry focus that can effect real changes in the way we think, design and build our physical environment. ", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2015-09-01"], "Project_ID": ["642877"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["UNIVERSITY OF DUNDEE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Dissecting spinal cord ependymal cell heterogeneity by single-cell transcriptomics"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ECtomics"], "Technology_Description": "Cells with stem cell potential, this is with the ability to self-renew and generate specialised progeny, exist in the adult mammalian spinal cord. Previous studies localised this potential within the ependymal cell (EC) population. However, ECs are rather heterogeneous based on their morphological features and the expression of a handful of neural stem cell markers. In this interdisciplinary research proposal, I aim to uncover the cellular and molecular heterogeneity of ECs at the level of individual cells. I propose to take advantage of cutting-edge single-cell RNA-sequencing technology to obtain the transcriptomes of individual ECs from the spinal cord of adult mice. Using advanced computational methods, I will establish EC types and states and use pseudotemporal ordering to elucidate potential lineage relationships among ECs. I will then validate these findings in the tissue context, using high-resolution confocal microscopy. This first comprehensive characterisation of spinal cord ECs will provide novel and fundamental insights into how ECs possess and maintain their unique self-renewing properties. In the future, this will facilitate realisation of the potential of spinal cord stem cells for therapeutic purposes.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["753812"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["TECHNISCHE UNIVERSITEIT DELFT", "SINGLE QUANTUM BV"], "EU_Contribution": ["EUR 100 000"], "Project_Title": ["Quantum Detectors"], "Total_Cost": ["EUR 100 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["Qdet"], "Technology_Description": "In HANAS (Hybrid Artificial and Natural Atomic Systems) storage in atomic quantum memories of single photons generated with novel quantum dot devices was demonstrated. Single photon detectors are crucial building blocks in quantum memories and in follow-up technologies such as quantum repeaters and the quantum internet. For our experiments in HANAS, single photon detectors based on semiconducting avalanche photodiodes were first used until a new type of single photon detectors based on superconducting nanostructures, originally developed for telecom wavelengths, was tested and greatly outperformed other detectors. This innovative detector makes complex quantum optics experiments far easier and faster to perform. In Qdet, we will develop and fully benchmark a prototype based on these superconducting quantum detectors optimized for atomic frequencies and start the commercialization process with an industrial partner. We will establish superconducting single photon detectors as the best systems for single photon detection in the near infrared, combining the highest detection efficiency, time resolution and lowest noise levels. A market research study and contacts with key players in the field will enable us to identify launching customers and benchmark our systems for demanding applications in a new wavelength range.", "To": ["2018-10-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-04-2016-2017 - FET Innovation Launchpad"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-05-01"], "Project_ID": ["754481"], "Call_for_Proposal": ["H2020-FETOPEN-4-2016-2017"]}, -{"Partners": ["FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS"], "EU_Contribution": ["EUR 100 000"], "Project_Title": ["Industrial Exploitation and Market Uptake of a Temporal Cognition Toolbox for Commercial Robots"], "Total_Cost": ["EUR 100 000"], "Country": ["Greece"], "Project_ACR": ["ENTIMENT"], "Technology_Description": "ENTIMENT aims to assess, deploy and commercialize a novel Temporal Cognition Toolbox (TCT) that greatly facilitates the development of time-aware robots, capable to engage in prolonged, symbiotic interaction with humans. In doing so, it significantly capitalizes on the successful research and development activities on artificial time perception, pursued within the FET-funded project TimeStorm, which aims at equipping robots with a human-like sense of temporality and the ability to perceive the temporal aspects of the world. The already available and tested robotic temporal cognition modules implemented in TimeStorm by partner FORTH, will be refined and integrated into the TCT, that will further be released as an open source ROS node for robotic developers. ", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-04-2016-2017 - FET Innovation Launchpad"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Greece"], "Activity": ["Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555"], "From": ["2017-07-01"], "Project_ID": ["754423"], "Call_for_Proposal": ["H2020-FETOPEN-4-2016-2017"]}, -{"Partners": ["UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN", "KUNGLIGA TEKNISKA HOEGSKOLAN", "KATHOLIEKE UNIVERSITEIT LEUVEN", "CHARLES OWEN & COMPANY (BOW) LIMITED", "LAZER SPORT NV", "AGV SPA"], "EU_Contribution": ["EUR 3 387 265,56"], "Project_Title": ["Head protection: a European training network for Advanced Designs in Safety"], "Total_Cost": ["EUR 3 387 265,56"], "Country": ["Ireland", "Sweden", "Belgium", "United Kingdom", "Belgium", "Italy"], "Project_ACR": ["HEADS"], "Technology_Description": "Head injury is the most severe injury caused by motorcycling, bicycling, snowsports and equestrian activities, and it is the leading cause of death within these activities. Linear acceleration has been used extensively to determine head injury risk, but it has been found that brain injury is actually influenced by angular kinematics. This is ignored by current injury criteria and product certification tests. To date, there is no consensus in terms of head injury due to angular kinematics and this represents a significant gap in the state of the art. The scientific goal of HEADS is to improve the understanding of head impact injury and to design new helmet standard test methods that recognise the influence of rotational kinematics. This will lead to improved helmets and a reduction in the severity of injuries and the numbers of fatalities. This objective will be achieved through a combination of computational simulations of real-life accidents, experimental and computational investigation of injury thresholds, and design of new helmet certification tests. Another major objective of the network is to train a group of highly specialised doctoral graduates who are equally cognisant of head impact biomechanics and helmet design technologies as well as being aware of commercialisable market opportunities. The ESRs will work in world-class facilities with highly qualified experts, and will benefit from the training scheme developed based on the expertise of academic and industrial partners. This project will reach a new level of understanding of head injury and how head injury should be prevented, with directly applicable results to European industry. It will develop a well-networked group of young engineers and scientists into world class researchers and innovators with numerous career paths open to them, who will advance technology for the benefit of society and maintain Europe as a global leader in industrial development.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["642662"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["SELUXIT APS", "AALBORG UNIVERSITET"], "EU_Contribution": ["EUR 100 000"], "Project_Title": ["Collective Adaptive Systems Enabler Kit"], "Total_Cost": ["EUR 100 000"], "Country": ["Denmark", "Denmark"], "Project_ACR": ["CASEK"], "Technology_Description": "In 2008 Apple introduced the App Store. It was a watershed moment in the history of digitalization and it made a huge impact on human society. With the App Store, Apple created a sustainable model to leverage the potential of mobile computing by tapping into the creativity of developers at large. ", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-04-2016-2017 - FET Innovation Launchpad"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Denmark"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["754506"], "Call_for_Proposal": ["H2020-FETOPEN-4-2016-2017"]}, -{"Partners": ["ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE"], "EU_Contribution": ["EUR 175 419,60"], "Project_Title": ["Two dimensional materials for lasing and frequency metrology"], "Total_Cost": ["EUR 175 419,60"], "Country": ["Switzerland"], "Project_ACR": ["2DQOptics"], "Technology_Description": "The recently discovered two dimensional 2D materials have opened up new possibilities for exploration of fundamental physics as well as device applications. Such materials offer new opportunities for ultra compact optoelectronic devices. On the other hand, with the improvement in micro and nanofabrication techniques, it is now possible to fabricate ultra high Q microresonators (UHQ \u00b5resonators). A relevant example is the case of silica microtoroids, which due to the whispering gallery modes, display one of the highest Q factors ever reported. ", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["753718"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Dressing Robotic Assistants for Persons with Reduced Mobility"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["DRAPer"], "Technology_Description": "Physical disabilities due to illness, injury, or ageing can alter the way a person moves around the house, manipulates objects and senses their home. These issues make it harder for persons to execute daily home activities on their own, and therefore specialized professionals are required to take care of them. However, the growing elderly population and the persons having basic activity difficulties or suffering from long-standing diseases are saturating the health systems due to insufficient infrastructures and over-demand for health carers. Robotics-based solutions are a promising alternative to support the human labour at health care. This project focuses on how robotic assistants can be exploited to provide independence and empower people with different kinds of mobility problems. Specifically, the main goal is to assist these persons in dressing themselves, which has been found to be an important task for independent living. In this sense, a robotic dressing assistant needs to skilfully manipulate clothes, physically interact with the human, recognize his/her intentions and actions, and easily adapt to changes in the clothing, user posture, and degree of mobility of the assisted person. These highly complex features are tackled in this proposal from a robot learning perspective, in which programming-by-demonstration, reinforcement and interactive learning will be combined to create both sophisticated manipulation skills and safe assistance behaviours. The proposal envisions three different real experimental scenarios to test the proposed approaches and show their performance with real (able-bodied) participants (with restricted motion). This project will not only advance the state of the art in assistive robotics, robot learning and human-safe control, but also will play a major role in helping persons with reduced mobility to live independently for longer and with a better quality of life.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2018-09-01"], "Project_ID": ["753556"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSIDAD COMPLUTENSE DE MADRID"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Using Phase Change Materials for the Base Suspension in the Creation of NanoFluids"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["PCMNano"], "Technology_Description": "Nano-fluids (fluid bases with a nano-particle suspension) and Phase Change Materials (PCM) provide innovative ways to handle the increased need for heat transfer and thermal efficiency. But information regarding the thermal properties (thermal conductivity, thermal diffusivity, enthalpy of transformation, enthalpy of fusion/melting, enthalpy of vaporization, specific heat, melting temperature, and crystallization temperature) of nano-fluids and PCMs is limited and antiquated. Therefore, is the purpose of this action to determine the thermal properties of a number of PCMs to then use as the base fluid for a number of nano-fluids. This will be done by measuring n-alkanes in both the solid and liquid phases using the transient hot wire and the differential scanning calorimetry (DSC) techniques. When possible, the obtained results will be compared with the scarcely available literature data. Lastly, the creation of a thermal properties prediction model for the nano-fluids will be attempted.", "To": ["2020-08-26, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-08-27"], "Project_ID": ["753319"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["DEUTSCHES FORSCHUNGSZENTRUM FUR KUNSTLICHE INTELLIGENZ GMBH", "UNIVERSITY OF SOUTHAMPTON"], "EU_Contribution": ["EUR 100 000"], "Project_Title": ["Bringing persuasive computing training assistance for healthcare personnel from lab experiments to educational practice"], "Total_Cost": ["EUR 100 000"], "Country": ["Germany", "United Kingdom"], "Project_ACR": ["SmartNurse"], "Technology_Description": "The aim of this proposal is to develop a strategy for transforming the results of a series of experiments in using persuasive computing technologies in emergency nurse training into a system that can be used in real life educational settings. The experiments were conducted as part of the SmartSociety FET Open project, which aims to develop new ways of human-machine collaboration. They were jointly done by the partners of this proposal with DFKI being in charge of the technology and Southampton providing the experimental setting within their nursing school that puts hundreds of professional nurses and nurse candidates through elaborate training simulations each year. The experiments have shown that sensor-based activity recognition combined with novel interaction techniques can, in principle provide significant benefit to both the students and the trainers. They also generate significant interest within the health care community, which included both enthusiasms for the potential and sepsis on potential problems. In this project, we want to understand which parts of the experiments are suitable for short to mid-term transition into real life education practice, how to overcome the corresponding technical, regulatory and social hurdles and how the introduction of such systems could be financed.", "To": ["2018-10-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-04-2016-2017 - FET Innovation Launchpad"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["754554"], "Call_for_Proposal": ["H2020-FETOPEN-4-2016-2017"]}, -{"Partners": ["THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Ecology and Evolution of Prospecting Strategies"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["EcoEvoProspectS"], "Technology_Description": "Prospecting behaviours allow individuals to gather personal and social information on the local quality of potential future breeding sites and help them make dispersal and settlement decisions. As it can have multiple consequences on individual distribution, fitness and population dynamics, exploring the ecology and evolution of prospecting strategies is essential in a context of climate change. Yet, studies dealing with this topic are scarce because of methodological and technological challenges. In this project, I will develop and apply novel theoretical and statistical approaches to deliver major new insights into the adaptive, ecological and evolutionary importance of prospecting strategies in individual and population responses to environmental change. First, I will develop a spatially-explicit individual-based model to quantify the effects of local environmental conditions, life history traits and range margins on the evolution of prospecting strategies. I will also test how inter-individual variation in these strategies may help or hinder populations in responding to rapid environmental change. Second, I will extend a state-space model to robustly quantify prospecting movements from GPS tracking data. This will provide an innovative and powerful tool that will give new insights into the behavioural mechanisms involved in breeding habitat selection. Finally, I will integrate the underpinning knowledge gained from the theoretical and empirical results to add new functionality to the existing platform RangeShifter. The multidisciplinary nature of the project is strong, involving a combination of evolutionary biology, behavioural ecology, movement ecology and conservation biology. The project will open new perspectives in our fundamental understanding of breeding habitat selection and dispersal processes and will be essential to better predict and effectively manage species\u2019 responses to climate change.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["753420"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ECOLE NATIONALE SUPERIEURE D'ARTS ET METIERS"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Porous material Analysis Toolbox - Open source"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["PATO"], "Technology_Description": "\"The objective of the proposal is to advance fundamental science in reactive porous material modeling to foster innovation on the second pillar of the work program \"Leadership in Enabling and Industrial Technologies\". Starting from the most advanced development done at NASA in the last decade, state-of-the-art reactive porous material models will be improved further with the contribution of expert theoreticians and implemented in a simulation tool released open source. The fundamental developments will be validated and applied to design optimization and process innovation for two industrial applications. The first one is the design of efficient and optimized thermal protection systems for space exploration vehicles (subprogram \"space\").The second one targets bio-hydrocarbon and bio-carbon production from lignocellulosic biomass. The biomass pyrolysis process will be studied from the wood-cell scale to the process level. The goal is to develop advanced predictive engineering tools to enable process optimization and guide innovation in progress. This second effort will eventually benefit to two \"Societal Challenges\" of the work program: \"Energy\" and \"Climate action, environment, resource efficiency, and raw materials\".\"", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["753412"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich"], "EU_Contribution": ["EUR 175 419,60"], "Project_Title": ["Generation and Evolution Of Transform-Ridge Interaction and Behavior on Earth"], "Total_Cost": ["EUR 175 419,60"], "Country": ["Switzerland"], "Project_ACR": ["GEOTRIBE"], "Technology_Description": "Transform-ridge orthogonal patterns are fundamental features of the Earth\u2019s plate tectonics. Although transform faults play a critical role in the organization of plate motions and are seismically active boundaries, it is still enigmatic how they form and why they are maintained. So far, only regional-scale models of transform fault inception and evolution exist. As the result, relationships of these structures with global mantle flow and large-scale plate kinematics remain unknown. The aim of this project is to advance our knowledge on global physical controls for the transform-ridge systems inception, dynamics and variability. I will take into account global forces to investigate nucleation and evolution of transform-ridge interactions, thus bridging the gap between regional and global models. I will use my long-term expertise in geophysical modeling to implement new physics (such as rock damage and magmatism) in the state-of-the-art convection code developed at ETH Zurich. I will run high-resolution 3D spherical models of global mantle convection to build the first database of simulated global transform-ridge patterns showing what factors influence the spacing and offset of transform faults. I will develop methods to compare the synthetic data with collected observed field data (bathymetry, gravity data, seismicity) to assess which physical processes (e.g. crustal melting, rock healing) control the formation and distribution of ridge-transform centers. Accounting for the global mantle and plate tectonic forces to explain transform fault dynamics is an unprecedented approach that is possible only now due to advances in physical properties of mantle rocks, numerical technics and increasing available computational power. Through this multidisciplinary project I aim at the first assessment of how transform-ridge system guides the evolution of plates for long periods with the scope of keeping Europe at the vanguard of the tectonics and geodynamical modeling research.", "To": ["2020-03-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-04-01"], "Project_ID": ["753755"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FUNDACION CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Long range-acting drivers of premetastatic niches in melanoma"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["METMEL"], "Technology_Description": "Melanoma is the cancer with the fastest rising incidence world-wide, and although recent therapies can achieve unprecedented response rates, a significant fraction of patients still succumb to metastatic lesions. Key pending questions in the field are the mechanisms underlying the inherent metastatic behaviour or melanoma, whereby seemingly thin primary lesions (\u22652 mm in depth) bear high risk of dissemination to proximal lymph nodes and ultimately, to distal sites. A dynamic crosstalk has been proposed to be established between melanoma cells and the lymphatic vasculature at tumour-draining lymph nodes, favouring an immune-permissive \u201clymphovascular niche\u201d. However, whether (and how) these lymphovascular interactions occur at distal sites is unclear. The Soengas group has generated unique \u201cLymphoreporter\u201d melanoma mouse models for non-invasive and whole body imaging of tumour progression. These lymphoreporters demonstrated that primary melanomas induce neo-lymphangiogenesis at distal pre-metastatic sites, already from very early stages of the disease, before dissemination occurs. Proteomic analyses were then performed to identify factors in the melanoma secretome that could drive these long range-acting effects and subsequently filtered these proteins for novelty (i.e. no previous link to melanoma and lymphangiogenesis). Here I will focus on the top-ranking factors in this screening. In particular, I will define the impact of these newly-identified melanoma secreted factors on tumour progression and metastasis, focusing on key components of the lymphovascular niche (i.e. on the crosstalk of tumour- vasculature-immune system). Secondly, I will assess the impact of these genes as prognostic biomarkers and indicators of response to clinically-relevant treatments. These studies will be performed in collaboration with dermatologists, pathologists and oncologist to define the physiological relevance of our work.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-04-01"], "Project_ID": ["753442"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["VRIJE UNIVERSITEIT BRUSSEL"], "EU_Contribution": ["EUR 172 800"], "Project_Title": ["A LAB-ON-A-CHIP DEVICE FOR PURE CIRCULATING TUMOR CELL ISOLATION FROM WHOLE BLOOD FOR CANCER THERAPY"], "Total_Cost": ["EUR 172 800"], "Country": ["Belgium"], "Project_ACR": ["pureCTC"], "Technology_Description": "The overall objective of pureCTC is to realize a comprehensive lab-on-a-chip platform that redefines the state-of-the-art technology to address all the requirements for fast, efficient and reliable CTC isolation/purification from whole blood.", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["752516"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE DE LIEGE"], "EU_Contribution": ["EUR 160 800"], "Project_Title": ["Characterization and monitoring of vigilance fluctuation in disorders of consciousness"], "Total_Cost": ["EUR 160 800"], "Country": ["Belgium"], "Project_ACR": ["ADOC"], "Technology_Description": "This prospective exploratory study will aim at characterizing vigilance fluctuation in patients with disorders of consciousness (as defined by a change in diurnal behavioral response over time) using neurophysiological parameters. We based this project on the assumption that changes at the Coma Recovery Scale-Revised scores (i.e., behavioral responsiveness) will be associated with a change in ocular measures and EEG complexity, suggesting that some of these parameters could be used for monitoring vigilance in this population. We expect that this fluctuation will be particularly marked in patients with a minimally conscious state as compared with patients in an unresponsive wakefulness syndrome who will display a more stable pattern of response over the two days. This project aims to better understand the course of vigilance fluctuation in DOC and to develop an objective tool based on biomarkers that could be used at bedside to determine the best periods to assess and treat these patients.", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["752686"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FUNDACIO CENTRE DE REGULACIO GENOMICA"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Comprehensive analysis of yeast expression-fitness functions (EFFs)"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["YEFF"], "Technology_Description": "Cellular and developmental processes rely on the precise activity of the proteins that constitute them, and alteration of protein activity often causes disease phenotypes and fitness defects. The relation between protein activity (or expression) and organismal fitness is thus a fundamental genetic property with implications for evolutionary and disease processes. However, a systematic understanding of how protein expression relates to fitness is lacking.", "To": ["2020-04-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2018-05-01"], "Project_ID": ["752809"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ACCADEMIA EUROPEA DI BOLZANO"], "EU_Contribution": ["EUR 180 277,20"], "Project_Title": ["Intergovernmental relations in divided societies"], "Total_Cost": ["EUR 180 277,20"], "Country": ["Italy"], "Project_ACR": ["IGR-IDS"], "Technology_Description": "Many divided societies in Europe and beyond are grappling with identity-based political tensions and conflicts. Most recent examples are the post-election violence in Kenya, the ethnic unrest in Ethiopia, and, in Europe, the continuing uncertainties about the territorial integrity of countries like Spain, the United Kingdom and Belgium in the face of secessionist claims. These and many other countries use territorial autonomies, within a federal or decentralised framework, to manage their divided societies. A lot of research has been conducted about the relevance of territorial autonomies for divided societies in general. What needs attention, however, and has been neglected by studies so far, is the integration of autonomous territories into the legal and political framework of the state, in particular, through their relations with the national government. Integrative intergovernmental institutions and processes are equally important because they serve as a vehicle for promoting a cohesive society and reconciling the tension between unity and diversity. The IGR-IDS project focuses on investigating the relevance and effectiveness of intergovernmental institutions and processes in the management of divided societies where territorial autonomies are used to deal with communal tensions. Using a comparative research method, it will identify and develop innovative integrative institutions and processes of intergovernmental relations. The successful completion of the project will advance my career by allowing me to explore new areas of study in the management of divided society and facilitate my recognition as a highly rated researcher. I will emerge as an established expert on intergovernmental relations in divided societies. That will put me in a position to progress on the academic ladder by placing a successful application for promotion to professorship.", "To": ["2020-06-03, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations"], "From": ["2018-06-04"], "Project_ID": ["752098"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FONDATION NATIONALE DES SCIENCES POLITIQUES"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["The Young Christian Workers Movement and the radicalization of Social Conflict in Mediterranean Europe: France, Italy and Spain (1963-1978)"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["WORK-CHRIST"], "Technology_Description": "\"The Work-Christ project intends to reconstruct the influence of religious radicalisation on the social conflict in Mediterranean European countries, with particular attention paid to the cases in France, Spain and Italy during the sixties and seventies. The main purpose of this research is to study the relationship between religion and politics in the period following the Second Vatican Council, via the study of the \"Young Christian Workers Movement\", better known by the French name Jeunesse Ouvri\u00e8re Chr\u00e9tienne. This is a field of research which is totally unexplored, both regarding the interactions among the different national offshoots of the movement and the transnational reality represented by the coordinating authority of the Jeunesse Ouvri\u00e8re catholique internationale. The research will also take into account the network constituted by the Mouvement Mondial des Travailleurs Chr\u00e9tiens (MMTC) to which the specialized branches of the working class Catholic Action organisations referred to. From the late sixties, the Christian workers\u2019 associations became the terminal point of the tensions, ferment and expectations that arose from the Second Vatican Council. In addition, these associations played an essential role in the processes of transition and consolidation of democracy in the three nations taken into consideration. For these reasons, the \u201cYoung Christian Workers Movement\u201d appears to be a case study of the utmost importance for the role played on a European scale as a workshop for the building of a radicalized young identity challenging societal norms. Work-Christ has 3 key objectives: 1. through research based on archive sources, address the innovative subject of international Christian workers\u2019 youth associations; 2. adopt a multi-disciplinary and interdisciplinary perspective for studying religious radicalisation; 3. study the mobilisation of the Christian workers associations at transnational level, reconstructing the phases, the goals and the contents.\"", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["751592"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Tuning both the photoluminescence and conductive properties of new COP materials"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["Tuning COPs"], "Technology_Description": "The main goal of this proposed project is the synthesis of new hybrid \u03c0-conjugated polymers for industrial use, which conductive and optical properties could be fine tuneable by the proper anionic metallacarboranes as doping agents. To achieve our goals two directions were chosen. In the first part we would like to investigate the effect of different boron clusters ([Co(C2B9HnX11-n)2]- X=Cl, Br, I) as doping agents on the conductive and photoluminescence properties of the poly(3,4-ethylenedioxythiophene) (PEDOT). Preliminary results suggest that the earlier used [Co(C2B9H11)2]- doping anion is redoxactive, thus it has a big influence on the formation and the properties of the polymer. Our expectation is that the halogen analogues ([Co(C2B9HnX11-n)2]-=Cl, Br, I) cover a wide range of redoxpotential, thus we can easily modify the properties of the new materials. During the second part we would like to tune both the conductive and photoluminescence properties of the poly(p-phenylene vinylene) (PPV). For this purpose different co-polymer planed to synthetized, which containing different amount of non-doped and self-doped monomer units. (In case of the self-doped polymer the doping anion is covalently linked to the monomer unit). We expect that the ratio of the non-doped and the self-doped has a strong influence both the conductive and photoluminescent properties, moreover the two different properties will be altered by the inclusion of functional side groups.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-10-01"], "Project_ID": ["751587"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Unique TNF\u03b1 lysine myristoylation; elucidating its function, regulation and integration into inflammation"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["TNFaLysMyr"], "Technology_Description": "Tumour Necrosis Factor-alpha (TNFa) is an important cytokine implicated in many autoimmune and inflammatory disorders, in which TNFa-blocking antibody drugs have become first line treatment. Nevertheless, clinical responses are variable. To improve and expand therapeutic strategies, a better understanding of TNFa and the many other cytokines secreted from cells is crucial. It was recently shown that TNFa is myristoylated on a lysine residue (KMyr), a unique modification that suggests an important but yet unexplored role for KMyr in cytokine biology. I will investigate the impact of KMyr on TNFa signalling, and its wider role in secretion and signalling of other cytokines, using a unique multi-disciplinary approach combining state-of-the-art chemical biology tools with molecular cell biology and proteomics. The role of KMyr in TNFa trafficking, secretion and signalling will be identified using human macrophage cell lines that produce mutant TNFa proteins with the relevant lysine residue substituted or deleted. KMyr proteins will be identified through a powerful approach that introduces a small chemical tag into the myristate in cells; this tag can be selectively functionalized to allow sensitive fluorescence imaging of KMyr within living cells, and purification for identification by mass spectrometry. The global scope of KMyr in the proteome will be analyzed in parallel, with emphasis on other secreted cytokines such as IL1alpha, which may be controlled too via KMyr. Regulation of TNF KMyr will be explored by identifying KMyr transferases and demyristoylases using chemical photo-affinity tools that can bind proteins interacting with KMyr, yielding putative targets for future first line therapies.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["752165"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAT POLITECNICA DE CATALUNYA"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["A database of experimental biomaterials and their biological effect"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["DEBBIE"], "Technology_Description": "The advent of material science and manufacturing techniques in the last century has led to the development of thousands of novel biomaterials, with potential to revolutionise health care. However, the vast majority of biomaterial studies do not progress beyond the stages of design and testing, and therefore a substantial amount of scientific data is only available in the form of research publications. To date, there is no database curating the experimental data generated by testing novel biomaterials in vitro and in vivo, representing a loss of a valuable big (experimental) data. In here, we propose an open-access database of experimental tissue scaffolds, indexing design features, cellular and tissue responses, thus creating an exhaustive inventory of experimental scaffolds. Such a dataset would enable scientists to efficiently search and interpret relevant information from past studies across all tissues and models, as well as create computational tools to predict and optimise cell-material interaction. A comprehensive map of research activity and findings should also make it easier to identify areas where data is missing or lacking. A systematic, up-to-date overview of the field will also be a useful tool for science policy making. The novelty of the project lies not only in the concept of curating data from laboratory evaluation of experimental biomaterials (rather than just approved medical implants), but also in attempting to face the methodological challenge of extracting and structuring information from the heterogeneous and vast field of experimental biomaterials. One of the keys of this interdisciplinary project is crowd-sourcing biomaterial scientists, thus engaging their expertise and understanding their needs, in order to create a comprehensive, relevant and useful tool to enhance research in the field.", "To": ["2020-04-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-05-01"], "Project_ID": ["751277"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["GEORG-AUGUST-UNIVERSITAT GOTTINGENSTIFTUNG OFFENTLICHEN RECHTS"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Ultrafast opto-electronic twists: Controlling the chirality of electrons and extreme-UV photons byultrafast laser pulses (UCHIRAL)."], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["UCHIRAL"], "Technology_Description": "Chirality, describing the \u201chandedness\u201d of a system, is a fundamental property of physical entities such as magnets, spins, the DNA double-helix, or circularly and elliptically polarized light. This proposal aims at employing intense ultrashort laser fields to control the chirality of two physical entities: photons of extreme-UV high harmonics, and free-flying electrons in a coherent pulsed beam.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["752533"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich", "University of California San Francisco School of Medicine"], "EU_Contribution": ["EUR 247 840,20"], "Project_Title": ["Patient specific magnetic resonance image guided biomechanical modelling of the heart \u2013 Anovel tool towards personalized medicine in heart failure"], "Total_Cost": ["EUR 247 840,20"], "Country": ["Switzerland", "United States"], "Project_ACR": ["CMRPredict"], "Technology_Description": "Heart failure (HF) is a progressing disease currently affecting 2% of the population in the developed world with a mortality rate of 50% within the first five years. While HF with reduced ejection fraction, primarily associated with myocardial infarction, can be detected with sufficient accuracy, HF with preserved ejection fraction is far more difficult to diagnose. Accordingly, there is an urgent need to better diagnose these patients to ultimately guide and improve treatment. Among the clinical imaging modalities, Cardiovascular Magnetic Resonance (CMR) is the gold standard for assessing cardiac mass and ejection fraction, and is capable to assess local cardiac mechanics and tissue properties. Beyond these established methods, cardiac diffusion tensor imaging has emerged as a new tool to enable insights into the microscopic morphology of the beating heart. Unfortunately, due to scan time limitations during clinical routine, compromises in spatial resolution and coverage have to be made. To overcome practical limitations of clinical in vivo CMR imaging and to enable prediction of disease progression for individual patients, additional tools are required. To this end, biomechanical models have attracted considerable attention. Once adapted sufficiently to in-vivo imaging, these models promise patient-specific insights into causes and progression of disease and, help guiding treatment. It is the objective of the present fellowship proposal to significantly advance patient-specific, image-guided modelling of HF by incorporating the most recent developments in both CMR imaging and biophysical modelling. The proposed framework will address limitations of current approaches, which impose generic assumptions about cardiac tissue properties and structure. With recent innovations in CMR imaging, as developed by the applicant, data on local changes of myocardial microstructure will be obtained to achieve the next level of diagnostic and predictive cardiac modelling of HF.", "To": ["2020-08-31, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-09-01"], "Project_ID": ["752466"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["LINKOPINGS UNIVERSITET"], "EU_Contribution": ["EUR 185 857,20"], "Project_Title": ["Towards Stable and Highly Efficient Tin-based Perovskite Solar Cells"], "Total_Cost": ["EUR 185 857,20"], "Country": ["Sweden"], "Project_ACR": ["TinPSC"], "Technology_Description": "Developing new energy sources is an urgent issue, as fossil fuels will be exhausted in near future. Solar cells system is a promising renewable energy technology that converts sunlight to electricity. Today, crystalline silicon exhibits high power conversion efficiencies (PCE) and dominates the solar panel industry. The problem of silicon solar cells is that it suffers from high production cost due to tedious processing condition. Recently, organic-lead-halide perovskites have offered the promise of a breakthrough for next-generation solar cell devices, and the PCE is up to 22.6% over the past few years. In spite of high efficiency, the presence of toxic lead (Pb) will become problematic in the future for widespread deployment of this technology. It is prospective to replace Pb with less toxic tin (Sn). However, the poor stability (the easily oxidization of Sn2+ to Sn4+ by O2) and low efficiency are two major issues of Sn-based perovskites. This proposal targets air-stable, high efficient Sn-based perovskite solar cells by developing new Sn-based perovskites and electron transporting layer to match the band energy of perovskites. The expected fruits of the project will contribute to European excellence and competiveness in renewable energy field. The successful transfer of the results will promote economic growth and job supplies. In addition to the scientific objectives, the proposal will help the fellow to new acquire knowledge and reinforce his quality as an independent researcher, such as creativity, independent thinking, leadership and transfer qualities, which are critical for the fellow to secure a long-term position in a European university/institution, and eventually become a world renowned expert in the energy research field.", "To": ["2020-07-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-08-01"], "Project_ID": ["751375"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Complex Dynamics and Strange Attractors through Non-Autonomous Bifurcations"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["CDSANAB"], "Technology_Description": "This project aims at substantial contributions to the bifurcation theory of non-autonomous dynamical systems. The main research efforts will focus on an analytical investigation of the principles behind the creation of complex dynamical behaviour and strange attractors in the most common kinds of non-autonomous bifurcations: saddle-node and Hopf bifurcations. The project further aims at an interdisciplinary application of the analytical findings to the problem of the predictability of ice ages.", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["750865"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Understanding how Inositol Polyphosphates regulate autophagy and lipid body formation in photosynthetic organisms: crosstalk with TOR signaling."], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["INSPirAUTOR"], "Technology_Description": "The elucidation of regulatory networks that govern cell growth and carbon storage in photosynthetic cells may potentially benefit the world's dependence on the declining reserves of fossil fuels. The growth/carbon sink relationship impacts metabolism, carbon partitioning and productivity but its regulation is poorly understood. Recently, we found a connection between two major cell growth regulators in the model green alga Chlamydomonas reinhardtii. Our findings revealed a synergistic effect between TOR kinase and Inositol polyphosphate (InsP) regulating lipid metabolism and the recycling process of autophagy. Based on the relevance of these results, we aim to find the mechanisms and the conditions in which this intersection takes place within the green lineage. In this sense, we have designed a straight-forward project including different goals. First, we will set novel analytical tools to evaluate the InsP level fluctuations in the presence of new TOR inhibitors and monitor the impact on autophagy flux and lipid metabolism in the model photosynthetic organisms Chlamydomonas reinhardtii and Arabidopsis thaliana. Second, we want to identify the phosphorylation targets of InsPs using Kinome/P-phosphoproteome in a Chlamydomonas InsP-deficient mutant. This analysis will unravel the phosphorylation network of InsP signaling and will provide new insights about the role of InsP in the control of cell growth. Third, we will evaluate InsP levels, autophagy flux and lipid storage under nutritional stress to determine the InsP modulation response in plants and algae. Understanding this signaling pathway will impact metabolic engineering of food and biofuel crops to improve yields of high-value products including oils and lipids. We believe this project will impact a general audience and will help to teach people how basic research can turn into a greater understanding of a process that is conserved in humans and has a direct economic impact.", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2018-02-01"], "Project_ID": ["750996"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["VIB"], "EU_Contribution": ["EUR 172 800"], "Project_Title": ["INTEGRATION OF PLANT ORGANELLE COMMUNICATION UNDER ENVIRONMENTAL STRESS"], "Total_Cost": ["EUR 172 800"], "Country": ["Belgium"], "Project_ACR": ["IN-PLANTO_CUES"], "Technology_Description": "Environmental challenges such as drought, temperature and light extremes can impose oxidative stress in multiple organelles, thus negatively affecting the function of plant cells. Both chloroplasts and mitochondria can invoke signaling pathways to the nucleus that trigger stress responses and adjustment of cellular homeostasis, resulting in physiological outcomes such as enhanced stress tolerance, or conversely programmed cell death. These pathways include the 3'-phosphoadenosine 5'-phosphate (PAP)-SAL1 pathway for chloroplasts and the ANAC013 mobile transcription factor for mitochondria. However, the mechanisms by which plant cells coordinate different signals from chloroplasts and mitochondria for whole-cell acclimation to oxidative stress are still enigmatic. Whether there is any cross-talk between chloroplast and mitochondrial signaling is also intriguing. My project will investigate these fundamental questions using an exemplar model system consisting of three components that combine my research with the Hosts\u2019. The first goal is to take my PNAS findings that SAL1 is a redox-regulated initiator of chloroplast signaling and determine if a similar mechanism occurs in the mitochondria, where SAL1 is also localized. This would reveal how two distinct organelles can integrate oxidative stress sensing and response by using the same pathway. Second, the interaction between SAL1-redox sensing and the mitochondrial signaling transducer ANAC013 will be investigated to understand integration between these two apparently distinct pathways. Third, ANAC013 targets a biosynthetic enzyme for PAP hinting at crosstalk between mitochondrial and chloroplast signaling at the level of signal metabolism. Thus, my research on SAL1-PAP and VIB\u2019s on ANAC013 collectively present a unique opportunity to reveal how the two pathways are linked at different levels enabling cellular signaling to be coordinated across scales to facilitate a harmonic, not discordant acclimation response.", "To": ["2020-03-11, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Belgium"], "Activity": ["Research Organisations"], "From": ["2018-03-12"], "Project_ID": ["750907"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["HASKOLI ISLANDS"], "EU_Contribution": ["EUR 179 325,60"], "Project_Title": ["Eruption Source Parameters for Explosive Eruptions in Iceland Over the Last 3 ka"], "Total_Cost": ["EUR 179 325,60"], "Country": ["Iceland"], "Project_ACR": ["ESPSI"], "Technology_Description": "Eruption source parameters (ESPs)\u2014such as erupted volume/mass, plume height, magma discharge, tephra dispersal, and total grain size distribution (TDGS)\u2014are key information for characterizing explosive eruptions and essential input parameters in tephra dispersal models used for real-time forecasting by the Volcanic Ash Advisory Centers (VAACs) and for long-term hazard assessments. Iceland is one of the volcanically most active regions of the world, with over 20 events per century. About ~700 events are preserved in the post-glacial soil and lake sediments in Iceland. ESPs, however, have yet to be determined for most of the eruptions. ESPs are traditionally derived using empirical approaches, requiring detailed field measurements of the deposits. The objective of this action is to estimate, to the first order, the ESPs for explosive eruptions in Iceland using inversion modelling. The advantage of this approach is that it bypasses the compilation of detailed isopach maps through the use of optimization algorithms. It requires only a limited number of thickness measurements and grain size analyses. Consequently, ESPs can be established for a larger number of eruptions in a shorter time, than when using traditional empirical methods. This will result in a statistically robust data set on ESPs used for determining the magnitude and intensities of explosive eruptions in Iceland as well as for assessing risk and mitigating hazards associated with such events.", "To": ["2019-06-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Iceland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-15"], "Project_ID": ["750733"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF SHEFFIELD"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Reuse of Waste Materials for Fire-Spalling-Proof and Crack-Resistant Sustainable Concrete"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["FireCracker"], "Technology_Description": "Fire-induced explosive spalling (violent peeling-off of concrete cover) and plastic shrinkage cracking are major issues for concrete infrastructure. Tunnels and buildings can experience catastrophic failure due to fire spalling, as well as premature deterioration due to cracking, leading to huge economic costs and loss of life. In any new project, EU directives and codes of practice require adequate solutions for the spalling/cracking problems whilst all major existing road tunnels need to be upgraded. However, the mechanisms of fire spalling and shrinkage cracking are not well understood, and there are no guaranteed spalling/cracking prevention measures.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["750764"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF LIMERICK", "THE UNIVERSITY OF SYDNEY"], "EU_Contribution": ["EUR 254 313"], "Project_Title": ["COsts and Mechanisms of Personalised Exercise and Education for chronic Low back pain"], "Total_Cost": ["EUR 254 313"], "Country": ["Ireland", "Australia"], "Project_ACR": ["COMPEL"], "Technology_Description": "Back pain is the leading cause of disability in Europe. Chronic low back pain (CLBP) is the most costly and burdensome form. As the EU population ages, there is an urgent need for more clinically and cost-effective therapies to ensure sustainable healthcare. Dr O\u2019Keeffe will explore a personalised medicine approach to exercise and education for CLBP. This is cutting edge, and has shown promising results beyond other therapies. Dr O\u2019Keeffe is the perfect match for this project, as she has led a trial on this novel therapy for her PhD. This will be the first project to examine the mechanisms, response, and the cost-effectiveness of personalised exercise and education for CLBP. This will build on Dr O\u2019Keeffe\u2019s experience to expand and develop her skills in this area. Dr O\u2019Keeffe will be trained in mediation, moderation and economic evaluation. She will gain additional research skills in new study designs, research software, physical activity measurement, gender analysis and public patient involvement. She will gain transferable skills in communication and public engagement, interdisciplinary networking, grantsmanship, project management, leadership and supervision. She will gain exposure to the non-academic sector through a secondment to a non-governmental organisation. Dr O\u2019Keeffe will disseminate her results through open-access journals and conferences. She will communicate her results and Marie Sklodowska-Curie experience through social media, TV, radio and European Research events. If awarded this fellowship, Dr O\u2019Keeffe will be equipped with the right skillset to improve her employability and reach a position of professional maturity. She will expand the European Research Area by strengthening networks. She will put Europe at the forefront of excellence and innovation for CLBP by promoting a safe exercise and education therapy for EU citizens. This will allow billions of euro that the EU currently spends on CLBP to be redirected to other health care services.", "To": ["2021-01-07, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-08"], "Project_ID": ["750492"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE BABRAHAM INSTITUTE"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Maternal Obesity and Epigenetic Reprogramming: from Gametogenesis to Early Embryonic Development"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["MOBER"], "Technology_Description": "Obesity is a worldwide epidemic with major health consequences. One devastating consequence of obesity is ovarian failure and infertility in women. Obesity causes endocrine dysfunction that compromises particularly the female gamete, the oocyte. Importantly, maternal obesity also affects the offspring, predisposing children to obesity and type 2 diabetes. ", "To": ["2019-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations"], "From": ["2017-12-01"], "Project_ID": ["750478"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSIDAD DE CORDOBA"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Fusarium oxysporum mediated underpinning of cell type-specific modulation in multiple host interaction"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["FOUNDATION"], "Technology_Description": "Fungi have a devastating impact on human nutrition and health. Each year, fungal pathogens provoke enormous agricultural losses in crop plants and contaminating food with harmful mycotoxins. The soil-borne fungal pathogen Fusarium oxysporum infects plant root and vascular tissue, causing wilt disease in over a hundred different crops, including both dicots and monocots. A particular aggressive strain of this pathogen, tropical race 4, is threatening banana plantations worldwide. Currently, there is little information on the crucial biotrophic infection stage of vascular pathogens, from penetration of root to colonization of xylem vessels. Fusarium provides an excellent model to investigate the cell-specific sensing and adaptation and suppression of plant immunity related to early infection stages. The host group has recently reported the chemotrophic sensing mechanism used by this pathogen, and identified host plant signals perceived by Fusarium in the soil. Moreover, their work revealed a combined action of enzymes involved in fungal cell wall remodelling and plant cell wall degradation which contributes in virulence of this pathogen. In this project, we aim to identify the cell-specific virulence genes that F. oxysporum uses to colonize a dicot host (Arabidopsis) versus monocot (Banana) that has a fundamentally distinct vascular tissue architecture. We will use dual RNA-Seq coupled with Laser capture microdissection (LCM) to identify core compatibility components in both the pathogen and the plant, that are essential for establishing wilt disease. This will lead to identification and characterization of potential targets in this interaction that could be used to develop novel resistance strategies in ongoing banana breeding efforts. This project will thus advance fundamental knowledge of how a fungus senses and colonizes such a broad host range, while creating new opportunities for crop protection by dissecting the interaction at a cell-type specific resolution.", "To": ["2020-06-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-07-01"], "Project_ID": ["750669"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF CYPRUS"], "EU_Contribution": ["EUR 151 648,80"], "Project_Title": ["The use of glazing traditions to examine the dynamics of interaction between cultures in contact: A case study of Cypriot glazed wares from the 11th to 17th centuries AD"], "Total_Cost": ["EUR 151 648,80"], "Country": ["Cyprus"], "Project_ACR": ["GLAZE"], "Technology_Description": "GLAZE seeks to investigate the suitability of using glazing traditions to reflect the dynamics of interaction between cultures in contact. Cypriot glazed ceramics dating to the 11th and 17th centuries AD, a period when fundamental socio-political changes occurred in the region, will constitute our principal case study. GLAZE has two key research questions:", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Cyprus"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["750904"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["LONDON SOUTH BANK UNIVERSITY LBG"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Biocementation for railway earthworks"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["BioRail"], "Technology_Description": "In a number of European countries, old railway transport infrastructure earthworks are suffering from serviceability problems or failures and need continuing and costly maintenance/remediation works. This is becoming a major constraint for railway owners and operators, especially in the light of the increased risk of hazards posed by climate change. The hypothesis of this research is that biocementation (a technique that uses natural biological processes to bind soil grains) is a viable and sustainable technique for improving the structural stability of railway earthworks, and hence, the resilience of the EU\u2019s transport infrastructure. The hypothesis will be tested through the application of the technique on earthwork materials of the UK rail network. After establishing improved microbial systems and processes, the project will involve advanced soil testing. The testing will give high quality data on the hydromechanical properties and behaviour of biocemented soils. Careful consideration will be given to the behaviour of the soil under unsaturated soil conditions (soil voids partially filled with water) which has not been researched. The data will be interpreted by constitutive modelling of the soil behaviour. The model will be implemented to commercial software, giving researchers and engineers a useful predictive tool for the analysis and design of biocemented soils. Having assessed the technique and the durability of the biocementation in the laboratory, a significant advance of this research will be the pilot application of the technique on actual railway assets, made accessible by a major owner and operator of railway infrastructure. This novel technique is proposed to be environmentally superior to conventional grouts (which are toxic) and other common soil stabilisers, e.g. cement or lime (linked to high CO2 emissions). Overall it is more sustainable because the micro-organisms used are renewable, environmentally friendly and safe (non-pathogenic).", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["750587"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Labelling of engineered nanomaterials for nanosafety tracing"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["NanoLabels"], "Technology_Description": "Major uncertainty still exists on the safety of engineered nanomaterials (ENMs). This is primarily due to difficulties in studying such small-scale objects and especially tracing their fate and behaviour in laboratory experiments and, even more so, the environment. Labelling of ENMs can serve a very important role of tracer in the environment, and ultimately be used as a tool to create unique ENM identities and support the concept of \u201csafer-by-design\u201d. The proposed project will compare different labelling techniques, both conventional (fluorescent labels) and emerging (stable isotopic and chemical labelling) where the host and ER have complementary expertise, and investigate multiple labels. It will consider aspects of industrial synthesis and scaling up and carry out a field experiment involving labelled ENMs. The ER will be hosted by the team who pioneered stable isotope labelling of ENMs and benefit from placements with the JRC and Glantreo, whilst bringing to the project his own unique expertise on ENM synthesis and tracing.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["750455"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITETET I BERGEN"], "EU_Contribution": ["EUR 208 400,40"], "Project_Title": ["Decadal changes in the Atlantic Equatorial Mode. Origin and dynamics."], "Total_Cost": ["EUR 208 400,40"], "Country": ["Norway"], "Project_ACR": ["DEMODA"], "Technology_Description": "Understanding the multidecadal variations of the Atlantic Equatorial Mode (EM) is important for climate prediction and climate services, because it is the first mode of variability in the tropical Atlantic in summer and has a worldwide impact on climate, including the West African Monsoon, rainfall in Nordeste (Brasil), European heat waves and ENSO phenomenon. ", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["750156"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ISTANBUL TEKNIK UNIVERSITESI"], "EU_Contribution": ["EUR 157 845,60"], "Project_Title": ["Microwave Diagnosis of Breast Cancer with Open Ended Contact Probes"], "Total_Cost": ["EUR 157 845,60"], "Country": ["Turkey"], "Project_ACR": ["MIDxPRO"], "Technology_Description": "This action proposes to carry out research in open ended contact probe (OECP) technique to lay out foundation work for development of two new applications: an automated surgical margin detection device for breast cancer treatment and an automated microwave biopsy probe for breast cancer diagnosis. While the envisioned applications require a single and highly accurate measurement, OECP technique suffers from high error and low repeatability dielectric property measurements. The error mostly stems from the current mathematical approach utilized for the dielectric property retrieval which may converge to local minimum and can magnify the measurement set-up based errors. This research will first target the existing error by proposing robust mathematical retrieval approaches. Next, application based modifications will be investigated with new probe structures. Finally, further error minimization will be achieved by introducing classification algorithms. Developed techniques will be validated with animal experiments. The outcomes of this research will greatly contribute to the innovation of new medical devices that can be utilized for breast cancer, representing one of the most commonly diagnosed cancer type among women. The researcher is well-equipped and has the required capabilities to execute the objectives of this research. The host organization and supervisors have an extensive track record in medical device development, necessary infrastructure, network, and expertise. This research will allow the researcher to become independent by extending her network, publication/grant track record, skill sets, and more importantly, through joining an innovation oriented host organization, the researcher will gain expertise in phases that enables the research to be transformed into innovation. Finally, the goal of the proposed research, building the foundation for innovation, is also in line with \u2018Future and Emerging Technologies\u2019 call of the H2020 work program.", "To": ["2019-05-07, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Turkey"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-08"], "Project_ID": ["750346"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich"], "EU_Contribution": ["EUR 175 419,60"], "Project_Title": ["Development of synaptic networks in songbirds"], "Total_Cost": ["EUR 175 419,60"], "Country": ["Switzerland"], "Project_ACR": ["DESYNE"], "Technology_Description": "Vocal learning in songbirds is a complex sensorimotor behaviour with many established parallels to human speech and language learning. Here we aim to resolve the neural ultra-structure of a key premotor area in the songbird brain, HVC (proper name). HVC plays a major role in song learning and takes part in both song perception and production. To understand the neural mechanisms of tutor song memorization and emergence of stereotyped adult song, we plan to map the networks of HVC\u2019s afferent and efferent synaptic connections and to explore the experience dependence of these connections during tutor-based song learning. ", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["750055"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAT WIEN"], "EU_Contribution": ["EUR 166 156,80"], "Project_Title": ["The King\u2019s City: A Comparative Study of Royal Patronage in Assur, Nineveh, and Babylon in the First Millennium BCE"], "Total_Cost": ["EUR 166 156,80"], "Country": ["Austria"], "Project_ACR": ["RoyalCities"], "Technology_Description": "Cities first developed in the fourth millennium BCE in Mesopotamia and quickly became the centers of civilization. Despite extensive work on urban landscapes from an archaeological perspective, these ancient cities remain poorly understood. Even less studied are royal capitals, the seats of kingship when empires emerged in the first millennium BCE. This project explores capitals from the two main, competing empires\u2014Neo-Assyrian and Neo-Babylonian\u2014to address key questions: what constitutes a royal capital and what distinguishes it from other important cities? How are capitals conceptualized by the kings who inhabit, establish, and renovate them? What are the effects of the kings\u2019 presence in and patronage of the capital cities on the urban fabric and the social and economic structure of the urban population? By juxtaposing the Assyrian capitals in Assur and Nineveh with the Babylonian capital of Babylon as case studies, this research uses a novel comparative approach based on a methodology that combines philology, religious studies, and social and political history to answer these questions. Uniting materials from the highest levels of state such as royal inscriptions, decrees, and letters with administrative, economic, and private archives, and joining these textual records with archaeological evidence through the lens of royal patronage, this project employs an innovative holistic and interdisciplinary framework to reveal how the kings\u2019 ideological and official relationships to their capitals affects the social and bureaucratic structures of these cities. The project capitalizes on the knowledge transfer between the researcher\u2019s Neo-Assyrian specialty and the host institution\u2019s Neo-Babylonian expertise. The project\u2019s results have great potential to revolutionize our understanding of cities and royal power in the ancient world, and to make accessible a wealth of new data for fields as diverse as history, anthropology, sociology, urban studies, and political science.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["749965"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["RIJKSUNIVERSITEIT GRONINGEN"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["Structure-function relationship of chimeric KdpFABC complex"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["KdpFABC"], "Technology_Description": "The structure-function relationships that explain the transport mechanism of membrane proteins on a molecular level are poorly understood and define one of the most complex and interdisciplinary research fields at the interface of Biology, Chemistry and Physics. Here I propose the investigation of the KdpFABC complex for the potassium uptake into the cell. It combines features of three membrane transport systems (P-type ATPases, channels and ABC transporters), which traditionally are considered to be mechanistically and structurally distinct. I propose to decipher the mechanism of action of the KdpFABC system, which is likely to overthrow the conceptual boundaries conventionally used to describe membrane transport mechanisms. The work might lead to the design of novel antibiotics, as these systems are exclusively found in prokaryotes. The structural studies will be conducted exploiting the recent breakthroughs in high-resolution single particle cryo electron microscopy (cryo-EM) that will be established by me as experienced researcher and thereby contribute to the cutting-edge research at UG. The complementary expertise of myself in structural biology and of Prof. Slotboom, as a world-leading scientist in the functional characterization of membrane proteins, are ideally suitable for the successful completion of the research objectives. Ultimately, this project will provide me a unique opportunity to establish myself as an independent researcher and use the knowledge and skills acquired to obtain an academic position within the EU.", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["749732"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6"], "EU_Contribution": ["EUR 246 668,40"], "Project_Title": ["Exploring the mechanisms underlying the evolution of plastids through the study of an unusual nitrogen-fixing symbiosis"], "Total_Cost": ["EUR 246 668,40"], "Country": ["France"], "Project_ACR": ["UCYN2PLAST"], "Technology_Description": "Symbioses are evident sources of innovation in nature, critical for the evolution of plastids and the success of eukaryotes on Earth. The mechanisms promoting such relationships, however, are difficult to identify, especially between single-celled organisms, and remain largely unknown. A widespread symbiosis was recently discovered in the ocean between an unicellular cyanobacterium (UCYN-A) and single-celled eukaryotic algae (prymnesiophyte). UCYN-A lacks typical cyanobacterial features such as the capacity to perform oxygenic photosynthesis, CO2 fixation or the tricarboxylic acid cycle, and must thus rely on the supply of organic matter from the algal host. In turn, UCYN-A shows a dramatic genome reduction with a high specialization in nitrogen fixation, providing fixed nitrogen to the alga. Given the importance of nitrogen for the algal productivity, it has been hypothesized that UCYN-A could eventually give rise to a nitrogen-fixing plastid in a process analogous to the origin of chloroplasts. This project aims to study the UCYN-A symbiosis both from an evolutionary and a functional point of view: First, the identification and characterization of new associations from marine samples at a global scale through molecular techniques will allow a deep comparison of closely-related symbiotic lineages that will help to understand the evolutionary underpinnings of this symbiosis. Second, nutrient incubation experiments of seawater samples over diel cycles will be performed to identify potential factors regulating the carbon and nitrogen exchange between partners to gain knowledge on the host-symbiont coupling mechanisms. For this purpose, metatranscriptomic analysis and electron microscopy combined with molecular probes and quantitative isotopic techniques (FISH-nanoSIMS) will be applied. Elucidating the mechanisms underlying this unusual nitrogen fixing symbiosis will provide valuable insight into previously unknown processes explaining the evolution of plastids", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["749380"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["Gravitational Waves and Electromagnetic Counterparts from Generic Binary Neutron Star Systems"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["BNSmergers"], "Technology_Description": "The research project will pave the way for a better understanding of the binary neutron star (BNS) merger process with a view on the detection of gravitational waves (GWs) and electromagnetic (EM) signals. ", "To": ["2020-01-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Research Organisations"], "From": ["2018-01-15"], "Project_ID": ["749145"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSIDAD DE SANTIAGO DE COMPOSTELA"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Photoresponsive Smart Nanocarriers for Tetherless Regeneration of Bone Tissue"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["PhotoNanoBone"], "Technology_Description": "The research aim of PhotoNanoBone is to develop of a novel nanotechnological strategy based on stimuli-responsive nanocarriers together with a microfluidic platform for spatiotemporal control of cell reprogramming and differentiation of 3D cell cultures towards bone tissue engineering. ", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["749667"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["SCUOLA NORMALE SUPERIORE"], "EU_Contribution": ["EUR 168 277,20"], "Project_Title": ["CACHEM: Probing Clustering of X-ray AGN using Chandra and Semi-Empirical Models"], "Total_Cost": ["EUR 168 277,20"], "Country": ["Italy"], "Project_ACR": ["CACHEM"], "Technology_Description": "The presence of a supermassive black hole (BH) in almost all galaxies in the Universe is an accepted paradigm in astronomy. How these BHs form and how they co-evolve with the host galaxy is one of the most intriguing unanswered problems in modern Cosmology and of extreme relevance to understand the issue of galaxy formation.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["749348"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["VRIJE UNIVERSITEIT BRUSSEL"], "EU_Contribution": ["EUR 172 800"], "Project_Title": ["Epistemic Optimism in Enlightenment Natural Philosophy : Metaphysics and Experimental Philosophy"], "Total_Cost": ["EUR 172 800"], "Country": ["Belgium"], "Project_ACR": ["EPISTOP"], "Technology_Description": "From a methodological point of view, the history of the classical sciences is often presented as a triumphant march of experimentation anchored in the science of Newton and the Newtonians. The historiography of 18th-c. scientific methodology tends moreover to portray each form of persistence of metaphysics as the sign of resistance to modernity or as some obsolete archaism. The aim of my research project is to bring a twofold shift to this traditional interpretation. First, by shedding light on the presence of other experimental traditions, some older than, some contemporary with the Newtonian one, that explain how Newton's natural philosophy was received and, second, by showing that within a certain number of 18th-c. scientific methodologies there was a fertile interaction between experimentation and metaphysics. The idea of the project is to propose a novel historiographical hypothesis about the epistemic values of Enlightenment science. My research hypothesis is based on an innovative methodological idea: namely that one should study epistemic practises in order to identify communities of shared epistemic values. This proposal will go beyond the classical divisions which have long dominated accounts of Enlightenment science (e.g. rationalists versus empiricists, Cartesians versus Newtonians, etc.). It will focus on the Dutch Republic from 1690 to 1750, because the aim is to scrutinize how Newton\u2019s Principia and Opticks were received within an already existing experimental context. The focus here will be on two questions that occupied 18th-c. scientists: What knowledge do experiments provide us with? And, how can it be rendered certain? To understand how the development of experimental philosophy in the Dutch Republic managed to reconfigure epistemic concerns without totally erasing metaphysical preoccupations. My intention is to test a research hypothesis: the epistemic optimism of 18th-c. natural philosophy.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["748623"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Enabling Multifunctional Plasmonics on Hybrid Artificial Scale-Integrated Systems"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["EMPHASIS"], "Technology_Description": "Optical isolator, or optical diode, is a device, which allows the transmission of light in only one direction. They are used in fibre optic communication to prevent back reflections and improve signal-to-noise ratio. The development of on-chip optical communications requires downscaling of optical components, e.g replacing optical fibres with nanoscale waveguides. The miniaturization of optical isolators is therefore a key step towards integrated photonic circuits. We approach this challenge by taking advantage of surface plasmon resonances that can squeeze light down to nanoscale dimensions. We combine plasmonic waveguides with ferroelectric and -magnetic materials that, in turn, break the space-inversion and time reversal symmetries to create non-reciprocal conditions for light propagation. The ferroelectric and magnetic materials provide us with an additional interesting advantage: their optical properties can be adjusted by applying external electric and magnetic fields, enabling active control over light in nanoscale. The proposed research project brings together the candidate\u2019s expertise in plasmonics and the hosting group\u2019s established knowledge in oxide thin films. This creates excellent conditions for training through research and knowledge transfer. We envision two significant outcomes: (i) demonstration of a proof-of-concept plasmonic isolator based on symmetry considerations and (ii) assessing the viability of using active oxide materials as tools to control plasmon propagation with external fields. The H2020 Innovation Union initiative strives to drive economic growth in the EU by innovation. In line with this strategy, we recognize that EMPHASIS offers ample potential for technological applications and include strategies to ensure that the potential can be realized.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2018-09-01"], "Project_ID": ["748429"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["HASKOLI ISLANDS"], "EU_Contribution": ["EUR 191 325,60"], "Project_Title": ["Household Ecology. Consumption and Wellbeing in Early Modern Iceland"], "Total_Cost": ["EUR 191 325,60"], "Country": ["Iceland"], "Project_ACR": ["HECoW"], "Technology_Description": "\"HECoW's aims are to quantify and qualify an observed increase in domestic consumption in early modern Iceland (1750-1900) in order to assess the effects new household material culture had on gender relations and the wellbeing of families. This will be achieved through an truly interdisciplinary, historical and archaeological, methodology applied to two different data sources: historical probate inventories and artefact assemblages from archaeological excavations. These sources will provide information on what new materials were consumed by families during this period, how their introduction and spread varied across the social spectrum, from poorer labourers to land owning farmers, and how they were distributed through time. ", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Iceland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["748698"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["BRITISH MUSEUM"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["The Western European Acheulian Project"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["WEAP"], "Technology_Description": "The Western European Acheulean Project (WEAP) aims to characterize the occupational pattern of western Europe during the Middle Pleistocene (MP) \u2013700 to 300Ka\u2013, through the study of Acheulean technology. Recent research has shown that the Atlantic seaboard is the most likely route for colonisation due to the more oceanic climate compared to eastern Europe and to the richer range of resources in coastal areas. Due to cyclical changes in climate with glaciations and interglacials, northern Europe was frequently depopulated and then recolonized through this period probably from source areas in southern France and Iberia. This route-way should therefore bear witness to the cultural links between north and south. From 1 million to 600,000 years ago there is evidence of brief pioneering events in north-west Europe with a small number of sites and small numbers of stone tool artefacts. After 600,000 year ago more sustained occupation is shown by the increase in sites and the much large stone tool assemblages. They also show technological innovation in the form handaxes and possibly in the use of fire, clothing and shelter, which led to the first sustained occupation of northern latitudes. Although there has been much research and new sites excavated over the last twenty years, there has been little integration between the work in Spain, Britain and France. Based on the applicant\u2019s previous experience, WEAP proposes to create a common method of analysis for the study of six Middle Pleistocene sites from UK and France \u2013in agreement with three Middle Pleistocene technologists\u2013, the use of the experimental technology to complete the archaeological record, and the use of new methodological approaches, such as the 3D scanning technology as the most appropriated statistical analysis, to improve understanding of behavioural patterns in order to build models of human dispersals from south-west to north-west Europe.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["748316"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSIDAD COMPLUTENSE DE MADRID"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Theoretical and Numerical Analysis of Antifreeze and Ice Nucleator Proteins:Coarse-Grain Approach for Multiscale Study and Bio-Engineering"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["ProFrost"], "Technology_Description": "In nature there are many organisms able to control the ice nucleation rate of water. This ability allows such organisms to adapt to environmental changes, like large temperatures excursions, and to facilitate the search for food.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["748170"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Active-site modulation of metal-ligand Coordinated complex electrocatalysts for PEFCs"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["CoordPEFC"], "Technology_Description": "In polymer electrolyte fuel cells (PEFCs), the commonly used catalysts are still carbon supported Pt-based nanoparticles (Pt/C), which undesirably increases the overall cost of the system. To address this challenge, advanced non-precious group metal (NPGM) catalysts have been endeavoured due to their potential low cost and high CO tolerance. Although rapid progress has been achieved in recent years, the poor activity and stability of NPGM catalysts can still not compete with the conventional Pt/C catalysts. ", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["747889"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Dissecting the chromatin dynamics at telomeres during mouse pre-implantation development."], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["TeloChromatin"], "Technology_Description": "In the last decades, the progress in medicine have contributed to extend human lifespan considerably. Unfortunately, this aging of populations gives rise to the increased appearance of degenerative diseases and cancers, and therefore represents a critical problem for public health. During embryonic development, cellular proliferation is an essential process that is required to generate all the tissues and organs that contribute to the adult organism. However, alterations in the molecular mechanisms regulating this fundamental process can drive developmental defects and tumors. Cellular fail-safe systems evolved to prevent these events to happen. One of them is the natural shortening of chromosome ends, termed the telomeres. This \u201cmolecular clock\u201d prevents cells from proliferating if their telomeres become critically short, which could lead to chromosomal alterations. This mechanism is responsible for cellular aging in Human. Unfortunately, cancer cells can bypass this process through the activation of telomere maintenance mechanism allowing for virtually unlimited proliferation. Interestingly, such maintenance mechanisms naturally occur during early embryonic development. The proposed research is aimed at understanding how telomeres are regulated in this system and under a physiological context. My expertise in mouse embryonic work associated with the competences in telomere biology of the host laboratory of Dr. Jerome D\u00e9jardin will likely be a suitable combination to answer these questions. On the long term, these researches could lead to the discovery of key factors regulating telomere maintenance. Finally, as the suppression of telomere length maintenance inhibits cell growth, the present proposal could contribute to the development of new treatments against cancer or precocious aging.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2017-07-01"], "Project_ID": ["748017"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE DE NAMUR ASBL"], "EU_Contribution": ["EUR 172 800"], "Project_Title": ["The virulence potential of human pathogens: how Acinetobacter baumannii survives Acanthamoeba castellanii predation"], "Total_Cost": ["EUR 172 800"], "Country": ["Belgium"], "Project_ACR": ["ACtIVAtE"], "Technology_Description": "The human pathogen Acinetobacter baumannii represents a deadly threat to human health. Despite its established clinical relevance, the pathogenicity of this nosocomial superbug is poorly understood. The biphasic amoeba Acanthamoeba castellanii is a cellular infection model broadly used to decipher the virulence mechanisms of human pathogens, as bacterial resistance upon amoebal predation (grazing) are often correlated with their pathogenicity potential in human. However, high-throughput screening approaches to investigate the virulence mechanisms of A. baumannii using this amoeba in an infection context are still lacking.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["748032"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["Transformations with Neutrals and Turbo analyses"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["TNT"], "Technology_Description": "The LHCb experiment at CERN was created in order to investigate decays of beauty and charm mesons produced in the proton collisions of the Large Hadron Collider (LHC). Through measurements of the observables in such decays, for example amplitudes and phases in the angular distributions of decay products, the effects of New Physics can be discovered. Disproving the Standard Model (SM) predictions through so-called flavour observables is an exciting approach to discover the answers to the questions the SM cannot solve, such as the source of the matter-antimatter differences necessary for our existence. The large backgrounds present in proton-proton collisions mean that large quantities of data must be processed, for example if all events were kept from the nominal LHCb luminosity, this would equate to ~50PB of raw data. The TNT project will enhance the physics abilities of the LHCb experiment, and will also dictate the future direction of Big Data analytics in High Energy Physics. The first two goals of this TNT project involve two new analyses of b\u2192s transitions decaying to neutral particles, namely Bd\u2192K*(\u2192KS\u03c00)\u03bc\u03bc and Bs\u2192\u03b3\u03b3, that provide complementary experimental inputs to New Physics searches. The study of these transitions will expand the physics case for the LHCb experiment and will involve the creation of new collaboration tools for the optimisation of all analyses with a single neutral particle. The third and final goal of the TNT project aims to optimise the LHCb data processing model through the extensive use of real-time analysis. Building on the success in 2015 and 2016 of the Turbo stream, allowing physics analyses to be performed with the LHCb trigger event reconstruction, the extension of this principle to flexibly save any required part of the event will transform the data processing model, permit all LHCb analyses to be performed in real time.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Research Organisations"], "From": ["2017-07-01"], "Project_ID": ["747822"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FUNDACION CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Role of infiltrating neutrophils in tissue homeostasis"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["TISSUENEU"], "Technology_Description": "Neutrophils follow daily cycles of release from and migration back into the bone marrow, where they are eliminated. After searching for the presence of neutrophils across multiple tissues of healthy mice under steady state, my host laboratory found neutrophils in most of the tissue analyzed. These findings require the study of the role of neutrophils in their tissue of destination. Several studies have shown that neutrophil clearance might be a significant source of homeostatic signals able to functionally modulate the tissues and organs where they are eliminated. In addition, specific functions for neutrophils in the spleen have already been described. I hypothesize that neutrophils may have important roles for the homeostasis and functioning of the tissues that they infiltrate, and that they acquire tissue-specific phenotypes that favor their local functions.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-05-01"], "Project_ID": ["748381"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Bogomolov Multiplier"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["BogomolovMultiplier"], "Technology_Description": "This project is dedicated to studying a geometric invariant called the Bogomolov multiplier. The main objectives of the proposed project are threefold.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["748129"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Origins and evolution of programmed cell death machinery during the emergence of animal multicellularity"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["HoloCellDeath"], "Technology_Description": "Programmed cell death (PCD) is an essential function in multicellular organisms; it regulates normal development, responses to cell damage, and cell turnover. Accordingly, the PCD machinery present in the unicellular ancestors of animals was likely critical to the emergence of the complex multicellularity found in extant animals. However, we lack a full understanding of the PCD repertoire in the unicellular relatives of animals, and whether that ancestral repertoire underwent significant changes at the onset of Metazoa", "To": ["2020-02-29, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2018-03-01"], "Project_ID": ["747789"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["Counterfactual Knowledge from the Imagination"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["CKI"], "Technology_Description": "Thoughts about counterfactual situations are a central feature of human cognition, key to planning in any domain of activity: What would happen if I missed a mortgage payment? What if Britain were to leave the EU? It seems that knowledge about counterfactual situations is possible under some circumstances. The project\u2019s general aim is to improve our understanding of those circumstances, and what role the imagination plays in specifying them. The specific objectives are to investigate: (1) the connection between the epistemology of counterfactual conditionals and the epistemology of claims involving modal terms like \u201cpossible\u201d, \u201cnecessary\u201d, and \u201ccan\u201d, (2) the role of the imagination in the epistemology of thought experiments in science, and (3) the cognitive architecture underlying counterfactual thinking. Over the course of investigating (1)-(3), I develop and defend the view that certain constrained imaginative exercises can provide knowledge about counterfactual situations.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["747658"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA"], "EU_Contribution": ["EUR 180 277,20"], "Project_Title": ["Definition, analysis and interpretation of a new typology of the Roman House: The TetrastyleCourtyard House, a domus with a hybrid cultural conception sheltered by a global civilization ofAntiquity"], "Total_Cost": ["EUR 180 277,20"], "Country": ["Italy"], "Project_ACR": ["TETRASTYLON"], "Technology_Description": "\"In the recent decades, some studies have found a particular typology of Roman house in different parts of the Empire. This typological feature is the result of a hybrid house scheme be-tween the Greek and Roman conceptions of the house. The new typology has been observed in different Roman cities with a Greek past, but in different geographical contexts and chronologies. This type of home, with its variants, has not been enough analysed by the Roman domestic architecture studies. There are still many Roman cities with a Greek past which private architecture has not been thoroughly studied. ", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["747466"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["AttoDNA: how electronic motions affect the photostability of the genomic material"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["AttoDNA"], "Technology_Description": "AttoDNA considers the early (attosecond to few-femtosecond) events following photo-excitation/ionisation in DNA/RNA canonical and non-canonical nucleobases for the first time. This involves the electronic movement before the onset of nuclear dynamics, ascertaining the length in which this initial purely electronic motion extends in time and how it affects the ensuing nuclear dynamics and its outcome with regards to the photostability shown by the genomic material from a bottom-up approach. By monitoring the electronic and nuclear motions in canonical and non-canonical nucleobases, the way in which they couple can be elucidated and the specific motions contributing to photostability extracted from a novel standpoint.", "To": ["2020-02-29, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["747662"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Photoacoustic and fluorescence imaging platform for biosensing applications: An innovative approach for the study of disease-related biomarkers"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["Photosense"], "Technology_Description": "In this Marie Sk\u0142odowska-Curie Fellowship (Photosense), I will design a photoacoustic and fluorescence imaging platform for the sensing of disease-related biomarkers, using conjunction rare-earth upconversion nanophosphors (UCNPs) with organic dyes to form kinds of nanoprobes. By incorporating UCNPs and dyes, I aim to efficiently develop a series of organic and inorganic hybrid nanoprobes. The fluctuations in the concentration of disease-related biomarkers can be monitored by fluorescence and photoacoustic signals simultaneously. Furthermore, this strategy can be easily expanded to detect different biomarkers by tuning and modifying the UCNPs and organic dyes pairs. I will apply my knowledge in multimodal imaging and nanoparticle design and carry out these exciting tasks in the labs of Prof Molly Stevens at Imperial College London (ICL), exploiting her research programme\u2019s expertise in nanomaterial-based components in biosensing technologies. My Fellowship will be best executed in The Stevens Group (2016 Clemson Award for Basic Research/2014 Research Group of the Year) based on their world-class technological knowhow in designing such systems to yield the best outputs from Photosense.", "To": ["2019-08-09, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-10"], "Project_ID": ["747206"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI PADOVA"], "EU_Contribution": ["EUR 168 277,20"], "Project_Title": ["Scattering Amplitudes for Higgs Production at High-Order as touchstone for Automated Multiloop Feynman Calculus"], "Total_Cost": ["EUR 168 277,20"], "Country": ["Italy"], "Project_ACR": ["HiProLoop"], "Technology_Description": "Scattering Amplitudes sit at the core of quantum field theory. On the one side, they capture the high energy regimes of fundamental interactions among elementary particles, hence, their accurate determination is a crucial test for the predictive power of the theoretical frameworks Particle Physics is based on. On the other side, scattering amplitudes are the tiniest mathematical lab of the Universe, where more formal investigations about the symmetries ruling particle interactions can be performed. New relations and dualities involving scattering amplitudes may become manifest only through their actual calculations at higher orders in perturbation theory, yet invisible to the canonical approach to quantum field theory. Therefore, progress in the ability of computing scattering amplitudes at very high accuracy is crucial for understanding the fundamental interactions and for providing accurate predictions within phenomenological analyses. HiProLoop aims at providing the most accurate determination of the virtual contributions to amplitudes relevant for Higgs phenomenology, by considering 1) the associated production of a Higgs boson and a jet at 2-loop, 2) the Higgs boson production in gluon fusion at 3-loop, as well as 3) the photon-pair production in association with a jet at 2-loop. The latter process is an important background to the process-1, and it can also be considered as a touchstone for the automation of generic 2-loop scattering amplitudes at high multiplicity. This effort should culminate in the development of a solid framework for the evaluation of generic 2-loop scattering amplitudes, which represent a currently open, urgent problem. Therefore the results of HiProLoop will become milestones for the theoretical physics community. HiProLoop will exploit mutual exchange of competences and tools between Theoretical Physics, Algebraic Geometry, Number Theory and Computer Science. The dissemination of the results will follow an ambitious communication plan.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["747178"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF LEICESTER"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Analysing the migration choices of HIV-positive gay men in England and France"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["HIVGAYM"], "Technology_Description": "Despite improvements in available therapies and investments in prevention campaigns, HIV-rates continue to rise across European cities. Gay men are over-represented amongst people with HIV, thus experiencing the combined effects of homophobia and HIV-related stigma. Several studies have found a correlation between becoming HIV-positive and gay men\u2019s decision to migrate, although most of them rely on quantitative methodologies and concern the US and Canada. In a European context we have very limited knowledge about the reasons why HIV-positive gay men choose to migrate to, and remain in, specific urban areas across the continent. This research project aims at addressing this gap in knowledge by investigating different migration patterns of HIV-positive gay men towards Birmingham and Brighton (England) and Marseille and Paris (France) at different historical times (the mid \u201880s/early \u201890s with the diffusion of the epidemic and a stigmatizing public discourse; the mid \u201890s/early 2000s with a new focus on prevention from health institutions and the introduction of effective therapies; the last decade with the introduction of a single drug-therapy and the recent introduction of Pre-Exposure Prophylaxis, PrEP). To better understand the complexity of factors pushing people to relocate and the perception of stigma in previous places of residence, data will be collected through questionnaires; in-depth interviews with both HIV-positive gay men of each generation and relevant stakeholders/policy-makers; and archival work to collect HIV-prevention campaigns, public health information and media news and reports among others. By shedding light on the dynamics of stigmatization still affecting HIV-positive gay men, the research project will provides an evidence base for policy makers and service providers in order to make their intervention for the well-being of HIV-positive gay men more effective.", "To": ["2020-02-29, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["747110"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CENTRO DE CIENCIAS DO MAR DO ALGARVE"], "EU_Contribution": ["EUR 160 635,60"], "Project_Title": ["Integrating conspecific odors into tilapia reproductive behaviour"], "Total_Cost": ["EUR 160 635,60"], "Country": ["Portugal"], "Project_ACR": ["FISHODOR"], "Technology_Description": "The aim of FISHODOR is to establish the identity of neural network components of the recently discovered tilapia reproductive pheromone. It will identify pheromone olfactory receptor(s) and their intracellular transduction pathways thereby increasing our understanding of olfactory perception and signal integration of fish pheromones. The project will determine the neuronal cell type (i.e. ciliated, microvillous or crypt-type olfactory receptor neurons) detecting the pheromone, it will establish the transduction pathways (i.e. AC/cAMP or PLC/IP3) involved in its olfactory detection and will identify the olfactory receptor(s) that binds the pheromone. If enough time is available it will attempt to map the neuronal network involved in the neuroendocrine response. The combination of electrophysiology, transcriptomics and molecular biology will bring high degree of novelty to explain the mechanism of action of olfactory receptor and neuronal signal integration.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Portugal"], "Activity": ["Research Organisations"], "From": ["2017-06-01"], "Project_ID": ["746507"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["BOURNEMOUTH UNIVERSITY"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Media Literacy for Unaccompanied Refugee Youth - A Path to Integration"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["MedLitRefYouth"], "Technology_Description": "According to Eurostat, 2015 saw 90,000 unaccompanied minor asylum seekers register in the EU. Refugee children pose considerable policy challenges: their integration in Europe is of utmost importance. Studies show that while refugee children have IT competences, they lack the ability to make critical media choices, and make informed decisions regarding their well-being. This project builds on the IT knowledge of young refugees in order to further their integration by developing media literacy pedagogic tools. Media literacy education is essential for empowering citizenship, for gaining skills to become drivers of economic growth, and not least to prevent radicalization. Media literacy, a necessary aspect of lifelong learning, enables young people to participate civically, to overcome disadvantage and to represent marginalized and missing voices. For developing these pedagogic tools, the Fellow will first research how unaccompanied minor refugees use digital technology and social media through fieldwork carried out in 3 EU countries. In the second research phase, the Fellow will conduct participatory action research (PAR) in collaboration with an NGO which specializes in PAR with refugee youth. These results will be used to design teaching materials for youth workers and teachers. The project is unique because it brings together the disciplines of education, media literacy and migration studies for offering solutions to a matter of pressing urgency: the integration of unaccompanied minor refugees. This project will serve to widen the professional horizon of the Fellow. She will acquire specific research skills (digital ethnography, participant action research, educational tools design) and transferable skills (PhD supervision, leadership, editorial skills, managing large-scale events). The project will lay the foundations for the Fellow's long-term career goals, and she will be propelled to the forefront of media literacy research.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["747083"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Highly symmetric partial linear spaces"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["HSPLS"], "Technology_Description": "The candidate proposes to investigate certain highly symmetric finite partial linear spaces using methods from combinatorics and group theory. A partial linear space consists of a set of points and a set of subsets of points called lines for which each pair of points lies on at most one line, and each line contains at least two points. Both linear spaces and simple undirected graphs are examples of partial linear spaces. For a class of graphs X, a graph G is X-homogeneous if any isomorphism between induced subgraphs of G that are isomorphic to a member of X can be lifted to an automorphism of the entire graph. This definition can naturally be extended to partial linear spaces for any class of partial linear spaces X. The candidate has two long-term research goals. The first is to understand X-homogeneous partial linear spaces S where X is the class of connected partial linear spaces (possibly with bounded size). This leads to two main research objectives. Objective 1 is to focus on the case when S is not a graph or a linear space, where nothing is yet known. Objective 2 is to continue her work on the case when S is a graph and the members of X have bounded size. The second long-term goal of the candidate is to understand partial linear spaces admitting automorphism groups of low rank, which again leads to two main research objectives. Objective 3 is to complete the classification of the primitive permutation groups of rank at most 5. Objective 4 is to use this classification to investigate certain partial linear spaces with rank 4 automorphism groups. These four objectives will enhance the expertise of the mathematical community. They will also lay the foundations for a future programme of research for the candidate and enable her to obtain a permanent academic position.", "To": ["2019-10-01, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-02"], "Project_ID": ["746889"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Synergistic Resistive Switching of Perovskite and Silicon Carbide materials for Advanced ReRAM micro Devices"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["PerovSiC"], "Technology_Description": "Perovskite oxides are one of the most promising materials for developing new ReRAM devices, because they show a Resistive Switching (RS) behaviour and multilevel (ML) storage properties through reversible nanoionics redox phenomena. However, several challenges remain to be addressed before introducing them in the emerging memories market. From a material point of view, it is still unclear how to tune and control the mass transport properties at the nanoscale to get the best resistive switch response. From a device point of view, the development of new heterostructures thermally and chemically stable and compatible with the microelectronics technology is required. The \u2018PerovSiC\u2019 project combines synergistically perovskite and carbide materials to overcome the current constraints. Starting from the recent breakthroughs of the hosting group, the project focuses on understanding the RS behaviour in perovskites using physical and chemical cutting-edge characterization methods. Further, computational modeling will allow improving the RS process in the new carbide-based heterostructures. The final optimized configuration will be integrated in a highly stable ML ReRAM device. The results of the project will lead to unexpected breakthroughs for neuromorphic computation, memories and logic devices. The multidisciplinary approach proposed will allow the researcher candidate gaining a deep understanding and specialisation in material science - acquiring new competences in advanced techniques, such as XPEEM and operando Raman - and in Key Enabling Technologies, such as micro-technology. Moreover, the collaboration with the ENSC-Lille and the Institute N\u00e9el will complement the researcher\u2019s training giving her unique skills in IEDP-ToF-SIMS and synchrotron measurements. Therefore, planned research and training activities in the \u2018PerovSiC\u2019 project will re-enforce a position of professional maturity in research and will provide the researcher new career perspectives.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2017-07-01"], "Project_ID": ["746648"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KING'S COLLEGE LONDON"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Race, Church, and Colonial Government in the Atlantic: the case of Angola in the age of Enlightenment"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ATLANTIC_ANGOLA"], "Technology_Description": "ATLANTIC_ANGOLA seeks to address the issue of race by analyzing its intersections with religion/church and colonial government in Angola in the second half of the 18th-century/beginning of the 19th century. Being the main provider of slaves to Brazil, Angola had a significant role for the economic success of the Portuguese South American colony, but also in the broader context of the Portuguese empire, due its privileged geographic position in the way between Asia and Brazil. That explains the increasing attention it started to receive from the Portuguese Crown after c. 1750. The aim of ATLANTIC_ANGOLA is to understand the role of the Catholic Church in disciplining and controlling the population, and instilling ideas of racial difference. The project hypothesis is that at least part of the population resisted the disciplining aims of the rulers. That resistance took different forms, but the result was the constitution of a creolized society, mainly in the city of Luanda and its hinterland. The project will contribute to the discussion of the relations between races and perceptions of the \u201cother\u201d in the context of the Portuguese empire. Doing so, ATLANTIC_ANGOLA proposes a path-breaking approach to problems still understudied concerning the history of European colonization of Africa before the 19th century. It will help to develop a better understanding of the historical dynamics of the relations between Europe and Africa over the longue dur\u00e9e. It will also contribute to the historical explanation of the long-term effects of the colonization and the formation of the post-colonial societies, but also to the perception both of the Europeans towards Africa and Africans, and those towards Europe. As to the more tangible outcomes of this project, they include 2 books, 3 articles in major peer-reviewed journals, 1 international conference, a talk series, and the setting-up of an online project.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["746581"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["INSTITUTO DE BIOLOGIA MOLECULAR E CELULAR-IBMC"], "EU_Contribution": ["EUR 148 635,60"], "Project_Title": ["Investigating how anaphase chromosomal motion is generated during mitosis and meiosis"], "Total_Cost": ["EUR 148 635,60"], "Country": ["Portugal"], "Project_ACR": ["ChromoDrive"], "Technology_Description": "Cell division is a process essential for life. There are two types of cell division: meiosis and mitosis. Meiosis is a type of cell division specific to germ cells, allowing the formation of fertilisation-competent sperm and eggs. Mitosis allows a single-celled fertilised egg to develop into a mature organism, and also allows tissues to be renewed. During each cell division, the cell must divide two copies of the genome equally between two daughter cells. Errors that occur during this process in oocytes can lead to spontaneous abortion and birth defects, whilst errors occurring in somatic cells can lead to genetic instability, a hallmark of cancer. It is therefore essential to understand how this fundamental process occurs. ", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Portugal"], "Activity": ["Research Organisations"], "From": ["2017-07-01"], "Project_ID": ["746515"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Reconstructing the origins of animal multicellularity using experimental evolution"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["MULTICELLEXPEVO"], "Technology_Description": "All living animals are descended from a single-celled ancestor. Understanding how this ancestor became the first multicellular animal remains a major challenge in the field of evolutionary biology. Phylogenomic analyses have shown that animals are closely related to three unicellular lineages: choanoflagellates, filastereans and ichthyosporeans, altogether forming the Holozoa clade. Genetic and phenotypic studies have shown that the filasterean Capsaspora owczarzaki can under specific growth conditions form transient multicellular aggregates. However, why is this multicellularity only transient? What are the genetic and phenotypic requirements for its emergence and stabilization? And what is the role of the actin cytoskeleton in this transition? Indeed the actin cytoskeleton is known for its pivotal role for cell coordination and morphology, which must play a role in evolution of multicellularity. To address these questions, we will use the C. owczarzaki as a model organism. We will combine cell biology, genomics and experimental evolution to unravel multicellularity emergence and stabilization. Specifically, we will aim to obtain evolved mutants showing excessive and more stable multicellular behaviour of C. owczarzaki using long-term experimental evolution. Such evolved strains would unravel how multicellularity emerged and stabilized. In addition, using random mutagenesis screen, we aim to identify mutants unable to form multicellular aggregates. Such mutants would reveal the minimum genetic requirements for such a transition. Finally, we will take advantage of recently developed genetic tools in C. owczarzaki to study the actin cytoskeleton during the cell cycle. Our results could reveal how the first multicellular ancestor of animals appeared from a genetic and cellular perspective, and, how cell fate specification was established during evolution. Results generated on this fellowship will be relevant to evolutionary, cell and developmental biologists.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2018-09-01"], "Project_ID": ["746044"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE"], "EU_Contribution": ["EUR 171 349,20"], "Project_Title": ["Rol of obligate bacterial symbiosis in the diversification of a globally distributed aphid genus"], "Total_Cost": ["EUR 171 349,20"], "Country": ["France"], "Project_ACR": ["MicroPhan"], "Technology_Description": "Plant-feeding insects represent a significant part of earth biodiversity but also encompass many plant pests that cause major losses to agricultural crops. One key factor in their evolutionary success probably resides in the mutualistic associations they have established with bacteria that reside in their cells. These endosymbionts metabolize some of the nutrients lacking in their host diet and can be essential for successfully shifting to new ecological niches. However, intracellular lifestyle also often results in severe genomic erosion for endosymbionts that limits their metabolic versatility and in fine affects their host adaptive potential. In this project we aim at deciphering the role of bacterial endosymbiosis in the long-term evolution of plant-feeding insects. The main question we want to address is whether the evolution of obligate bacterial endosymbionts played a significant role in the diversification (speciation and extinction) of their hosts. Using the genome sequences of the main bacterial endosymbionts associated with a globally distributed aphid genus, we will: 1) reconstruct the history of aphid/symbiont associations by conducting phylogenomic analyses; 2) identify the footprint of selection and genetic drift in bacterial genomes by comparing patterns of molecular evolution within and between symbiotic bacterial lineages; 3) illuminate how changes in the endosymbiont community metabolic capabilities have accompanied aphids evolutionary transitions (host plant shifts, climatic tolerance, rates of speciation) using phylogenetic comparative methods. Using the data from an ongoing large sequencing project, this project will combine recent methods in phylogenomics, metabolic network analyses and the study of macroevolutionary processes. With this fellowship, the applicant will lead an exciting and innovative multidisciplinary project, supervised by international experts in microbial evolutionary genomics and insect macroevolution; this project will cre", "To": ["2020-06-14, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2018-06-15"], "Project_ID": ["746189"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KOC UNIVERSITY"], "EU_Contribution": ["EUR 157 734"], "Project_Title": ["ANXIETY IN INTERNATIONAL POLITICS: MEDIATING EFFECTS OF NORMS"], "Total_Cost": ["EUR 157 734"], "Country": ["Turkey"], "Project_ACR": ["ANXINT"], "Technology_Description": "This interdisciplinary research project examines how anxiety impacts individual \u2013level political attitudes toward international issues, and in turn how prevalence of anxiety interacts with nativist and cosmopolitan norms in shaping international political attitudes. Bridging the fields of International Relations (IR), Psychology, and Philosophy, the research project will contribute to the distinct but related literatures on ontological security, emotions, and norms in IR with a systematic analysis of anxiety. In its outgoing phase at the University of British Columbia, the research will focus on the development of a novel conceptual/ analytical framework linking anxiety, norms, narratives and international political attitudes drawing primarily on existentialist philosophy and terror management theory in psychology. In the second phase at University of Columbia and the third phase at Koc University, the research will derive comparative cross-cultural findings from experimental analyses conducted with university students at UBC in the outgoing phase and at Koc University (KU) in the reintegration phase.", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Turkey"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["746155"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Photoexcitation Dynamics and Direct Monitoring of Photovoltaic Processes of Solid-State Hybrid Organic-Inorganic Perovskite Solar Cells"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["PHOTOPEROVSKITES"], "Technology_Description": "Abundant, cheap and clean source of energy is fundamental to preserve global environment and sustained economic growth. Solar energy is considered as the ultimate solution in this regard. Among the three generations of solar cells developed with this objective, hybrid organic-inorganic perovskite solar cells with demonstrated power conversion efficiency (PCE) of over 22 % have bagged the greatest attention. Despite the impressive PCE, lower cost and facile processing opportunities for hybrid perovskite solar cells, their commercialization is not yet realized; poor stability, lack of robustness to subtle variations in processing, and Pb toxicity being the bottlenecks. We take up the view that pursuing fundamental understanding of the photophysics and photovoltaic process of these highly efficient lead halide perovskites can contribute to tackle their instability issue and also to the development of Pb free organic-inorganic halide perovskites with analogous optical and photovoltaic performance to that of former, expediting their market entry. Apart from photovoltaic sector, the fundamental knowledge evolved through this project is expected to have direct impact on the fabrication of high performing photodetectors, lasers, and light emitting devices based on hybrid perovskite materials. This interdisciplinary project lying at the interface of material science, physics and chemistry is expected to bring a breakthrough in perovskite solar cell research arena.The proposed project will utilize the applicant\u2019s expertise in the fabrication of high efficient organic and perovskite solar cells in combination with world leading scientist Prof. Ifor Samuel\u2019s expertise on photophysics aspects of thin film solar cells and the excellent infrastructure facilities at the host institution. In implementing this ambitious project, I will gain expertise on the photophysics and photovoltaic processes (under real operating conditions) of hybrid perovskite thin films and solar cells.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["745776"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich"], "EU_Contribution": ["EUR 187 419,60"], "Project_Title": ["Properties across dimensions: an atomistic computational study of bismuth ferrite surfaces and nanocrystals"], "Total_Cost": ["EUR 187 419,60"], "Country": ["Switzerland"], "Project_ACR": ["BFO-Surf"], "Technology_Description": "Bismuth ferrite (BFO) is one of the few multiferroic materials at room temperature. It is of interest for use in memory elements, spintronic and photovoltaic systems, to name but a few. In all applications, the use of BFO thin films and nanoparticles is being greatly investigated, due to their greater fatigue resistance and larger polarization at modest electric fields with respect to the bulk. However, reducing the dimensionality of BFO can lead to surprising and so far unexplained behaviour. For example, recent experiments have reported the existence of a surface \u201cskin\u201d above bulk-truncated BFO, with different lattice parameters and phase transitions than the underlying bulk. This surface skin layer exhibits strikingly different properties from the bulk, since it is ferroelastically and ferroelectrically dead. It is thus of paramount importance, for practical applications of BFO, to understand how 2D structures (like thin films) and 1D structures (like nanocrystals) differ in their multiferroic behaviour from the relatively well understood bulk phase. Since surfaces are dominant in these two classes of systems, a good atomistic understanding of low-energy surfaces and their stability in the environment is needed. Thus, we propose a two-year project with the overall aim of studying the atomistic structure and the magnetic and polarization properties of BFO thin films and nanocrystals using using ab initio methods (density functional theory with ab initio thermodynamics).", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["744027"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CARDIFF UNIVERSITY"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Self-healing geological construction materials and structures"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["GEOHEAL"], "Technology_Description": "Geological materials are used in significant quantities for construction purposes, structurally and for cladding, but are subject to damage, deformation and deterioration through natural weathering processes in combination with the stress state induced in service. As a consequence, structural performance can be reduced, durability is compromised and there may be aesthetic or heritage issues with regard to preservation of the original structural form. Currently, such issues are addressed either through initial overdesign, implementation of maintenance programmes, or both. The proposal seeks to explore the potential for providing such materials with the ability to self-heal \u2013 to automatically respond to damage or deterioration, instigating a healing process that restores or even enhances the desirable structural or aesthetic properties. Such technology will take inspiration from, and work in parallel with, current research into self-healing in cementitious, polymeric and other engineering materials. ", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["745891"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF SHEFFIELD"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["High Attenuation Recycling Materials as sustainable barriers for waste disposal sites"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["HARM"], "Technology_Description": "The need to minimize the amount and foster the safe treatment of waste, and thereby reduce the risk of contamination; emphasises the importance of promoting technologies which are environmentally sound with products suitable for re-use/recycling. This project establishes a laboratory experimental study to determine the performance of clay mixed with construction and biomass plant waste (fine recycled aggregates, FRA, and/or biomass bottom ashes, BBA) as materials for the enhanced attenuation of contaminants in landfill leachate. The aim is to (1) evaluate the contaminant attenuation capacity of these mixtures for different conditions, (2) develop design guidelines to construct barriers for waste containment systems and similar applications, and (3) interpret their performance using numerical modelling tools. Column experiments where landfill leachate is passed through different waste:clay mixtures will be run in a state-of-the-art centrifuge facility which simulates realistic times, pressures and temperatures of landfill field conditions. The geochemistry of the column pore water and material residues after permeation with leachate will be examined to deduce the processes responsible for pollutant removal and retention. After permeation with landfill leachate, the effects of exposure of these barriers to an aggressive acid environment, rainfall infiltration and rising water table will be studied. The concept will be applicable for barrier design at other waste disposal facilities. The results will provide a novel and timely improvement which addresses the problem of managing the vast amounts of industrial residues such as FRA and BBA. Instead of disposal these will be re-used/recycled as an additive in host clay for building contaminant barriers, thus also conserving natural resources (clay and other man-made barrier materials). It will also provide an effective and more environmentally sustainable basis to control landfill pollution risks.", "To": ["2020-02-22, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-02-23"], "Project_ID": ["743880"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF NOTTINGHAM"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Advanced modelling of ultrasonic wave interaction with damage for enhanced failure identification technologies in industrial composite structures"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["UltraSafe"], "Technology_Description": "The EU is a world leader in the transport industry, with the aeronautical sector alone providing more than 500,000 jobs and generating a turnover of EUR 140 billion annually. Development of structural safety technologies have always been of paramount importance for Europe. With regard to the aeronautical sector, approximately 1.3 billion passengers fly around the globe every year, rendering aviation safety a major societal challenge worldwide. Flightpath 2050 sets out a vision for a future aerospace industry placing airworthiness at the heart of technology developments in order to keep Europe competitive in this strategically important global industry.", "To": ["2020-02-24, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-02-25"], "Project_ID": ["741284"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["BCBL BASQUE CENTER ON COGNITION BRAIN AND LANGUAGE"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Cognition, ageing, and bilingualism: Investigating age-related changes in bilingual language switching and use."], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["CAB"], "Technology_Description": "Older adults show difficulties with bilingual language processing and switching compared to younger adults. For example, they need more time to switch between languages and show more cross-language intrusions. Language problems have not only been found for healthy older adults, but also in patients with dementia and Parkinson\u2019s disease. Language deterioration could be used as an early disease marker to improve diagnosis. However, the exact nature of bilingual language problems in healthy older adults needs to be studied first. Besides language deficits, older age has also been associated with deficits on executive control tasks (e.g., inhibition and switching tasks). While executive control is argued to be needed during (bilingual) language production, it is unclear how the two relate in older adults. Although some studies have found similarities between language and cognitive control, others found deviating patterns. ", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["743691"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["MEDICAL RESEARCH COUNCIL"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Assessing Causal Relationships of Oscillatory Neural Activity Mediating Speech"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ACRONAM-Speech"], "Technology_Description": "Neural oscillations, rhythmic fluctuations in the excitability of neuronal populations, align their phase to the rhythm of speech and this mechanism, called phase entrainment, has been associated with successful perception of connected speech. However, a causal role of phase entrainment for speech comprehension has not yet been shown which leaves the underlying mechanisms unclear, and fails to specify the relevance of neural oscillations for hearing or language impaired individuals. In the proposed research, we will use a novel brain stimulation technique, transcranial alternating current stimulation (tACS) to selectively alter neural oscillations. By manipulating neural phase entrainment to speech with tACS we can, for the first time, provide decisive evidence concerning whether phase entrainment and speech comprehension are causally linked: If a modulation of phase entrainment leads to changes in speech perception and comprehension we can conclude that the former causally influences the latter. In a preliminary experiment, combining tACS with functional magnetic imaging (fMRI), we will determine the optimal tACS electrode montage to modulate neural activity in speech-specific brain regions (in the superior temporal gyrus). Using this setup in a behavioural task, tACS can be applied at different phase-lags in relation to rhythmic speech sequences. Critically, we expect perception of these stimuli to depend on the phase relation between tACS and speech rhythm, as a consequence of the manipulation of phase entrainment by tACS. Our study will thus provide important and novel evidence for a causal role of phase entrainment for speech perception and comprehension. In turn this might suggest new methods for enhancing speech perception in populations with hearing or language impairment.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["743482"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Efferent modulation of auditory sensitivity in mosquitoes: From auditory transduction to swarming behaviour"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["NEURO-SWARM"], "Technology_Description": "Hearing in mosquitoes is crucial for mating partner recognition. Within mating swarms, males hear the wing beat of females and chase them to copulate. Despite the importance of this behaviour, very little is known about the molecular mechanisms involved. I and my co-workers have recently discovered an auditory efferent system innervating the mosquito hearing organ, the Johnston's Organ (JO) that releases the biogenic amines octopamine and serotonin and modulates the auditory function. However, we still do not know how this efferent system modulates hearing in the context of swarming. ", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["752472"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE HEBREW UNIVERSITY OF JERUSALEM"], "EU_Contribution": ["EUR 170 509,20"], "Project_Title": ["Statistical learning and second language acquisition: individual differences and neurobiological underpinning."], "Total_Cost": ["EUR 170 509,20"], "Country": ["Israel"], "Project_ACR": ["INDIV-STAT"], "Technology_Description": "Consider a Libyan immigrating to Italy, or a businessman relocated in Tel Aviv. Reading in a second language would be a prerequisite for a successful assimilation in a new country. How is this formidable task achieved? The overarching goal of INDIV-STAT is to provide a deep understanding of second language (L2) literacy acquisition by tying individual abilities in language learning to the domain-general capacity to detect, store, and use statistical regularities in the input. The project brings together (a) behavioral research on individual differences in statistical learning (SL), and (b) a controlled investigation of the neurobiological basis of SL capacities. It launches a set of mutually informative research axes: First, given the large individual differences in L2 learning, we develop psychometrically reliable behavioral tests of individuals\u2019 capacities to extract regularities in the visual and auditory modalities, to better measure behavioral SL, and serve the subsequent experimental packages. Second, we use EEG and MEG, targeting the what, where, and how of SL, probing its neural underpinning. By obtaining reliable brain signatures of the neural dynamics associated with SL we will be able to examine the detection of language-related regularities for print and speech during L2 learning. Third, we launch a series of behavioral experiments to investigate the link between individual capacities in SL, and the ease or difficulty of L2 literacy acquisition. Finally, we evaluate whether we can experimentally enhance the process of acquiring literacy in L2 by enhancing participants\u2019 sensitivity to regularities. The project will offer an empirically-validated neurobiological theory of how the specific statistical properties of a language are assimilated during L2 literacy acquisition, addressing also individual differences in learning capacity. This will have important educational and societally implications.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["743528"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["The effect of seagrass bed habitat quality on selected ecosystem services"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["PIONEER"], "Technology_Description": "Seagrass meadows serve many important ecosystem functions and services in coastal waters. Most notably, through their role as nursery and feeding areas they support a great abundance and diversity of fish and invertebrates, making them important for fisheries and local economies. In spite of their ecological and socio-economic importance, seagrass meadows worldwide have been experiencing declines and habitat degradation through fundamental changes in their structural complexity. Currently only limited knowledge exists of how these configurational changes influence the functioning and the ecological and cultural services provided by seagrasses. Through a combination of ecological and social data collection methods that include citizen science, PIONEER takes an interdisciplinary approach to assess how changes in the environmental status of Posidonia oceanica ecosystems affect important ecosystem services for both marine biota and humans in the Balearic Islands, namely (i) seagrass nursery function for juvenile fish, (ii) food provision capacity for adult fish and fishers\u2019 perception of the recreational fishing sector. PIONEER provides relevant and timely information for the implementation of the EU Marine Strategy Framework Directive, which aims to achieve Good Environmental Status in all water bodies across EU member states by 2020. Findings from this project will be relevant for both conservation and management of these habitats; dissemination of results will target scientists, governmental and non-governmental authorities and end-users of seagrass habitats. The fellowship contributes to the candidate\u2019s career development mainly through the acquisition of advanced skills in ecological and social sciences that will provide a notable improvement to her multidisciplinary background and diversification of research expertise, as well as enlarging the international network of professional contacts to southern Europe.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2018-01-01"], "Project_ID": ["740481"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FONDAZIONE EDMUND MACH"], "EU_Contribution": ["EUR 176 203,80"], "Project_Title": ["GUT biota indices: a new tool for WILD animal conservation"], "Total_Cost": ["EUR 176 203,80"], "Country": ["Italy"], "Project_ACR": ["WILDGUT"], "Technology_Description": "Calls to stem biodiversity loss have generally focussed on the plight of charismatic vertebrates (mammals, birds, fish, amphibians) and to some extent, insects (like butterflies). However, although the abundance and diversity of microbial and helminth communities inhabiting the gastrointestinal tract have been demonstrated of critical importance to health in both humans and non-human animals, this microbiodiversity has rarely been considered within a conservation framework. Using recently collected fecal samples from two free-ranging tropical non-human primate species with contrasting ecological parameters, WILDGUT proposes a multi-disciplinary approach to investigate the four-way interplay between habitat changes, host species, and gut micro- and macro-parasites in natural environments. The results will lead to a better understanding of the impact of human activities on microbiodiversity, and whether such changes could have an effect on wildlife health, and ultimately to a species\u2019 conservation status. Thus, the project will explore whether the comparison of gut microbiota and helminth community diversity, functions and interaction between intact and degraded habitats can be used to develop new indices to estimate host health and informing conservation strategies.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["752399"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["FRAGMENT screening from advanced-sampling molecular dynamics simulations on a proteOME scale."], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["FRAGMENTOME"], "Technology_Description": "In Fragment-Based Lead Discovery (FBLD) highly sensitive biochemical and biophysical screening technologies are used to detect the low-affinity binding of low-molecular-weight compounds (the so-called fragments) to biological targets that are involved in pathophysiological processes. Knowledge of the molecular interactions between fragment hit(s) and the target protein allows the rational generation of high-quality leads for drug development. Thus, high-resolution (e.g. X-ray crystallography) and relatively high-throughput structure determination technologies are key to this approach but they can become a limiting factor for both technical and economical reasons. As a matter of fact, when the experimental characterization of binding mode fails, the success rate of FBLD approaches drastically drops. To overcome current limitations in FLBD, here we propose the development of a computational framework based on advanced-sampling molecular dynamics simulations to map the binding of fragments to protein surfaces on the proteome scale---thus generating the Fragmentome Altas. For each individual target this will allow to: a) systematically identify fragments binding to protein surfaces and cryptic pockets; b) reconstruct the mechanism of binding with atomistic spatiotemporal resolution; c) characterize the molecular determinants of affinity and kinetics in fragment-protein complexes. This insight is fundamental for optimizing and evolving fragments to lead compounds with desired thermodynamics and kinetics features. To date, neither experimental nor computational approaches can provide such information at affordable costs while maintaining the high throughput needed for screening campaigns. The successful implementation of this ambitious project lies in the unique combination of expertise of its participants, and it will allow a novel state-of-the-art for modern drug discovery to be established. The Fragentome Atlas will be a freely accessible on-line server.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-05-01"], "Project_ID": ["752415"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF EAST ANGLIA", "UNIVERSITY OF EAST ANGLIA"], "EU_Contribution": ["EUR 149 115"], "Project_Title": ["Highly Efficient Photoemitters for Light-Emitting Diodes Based on Intramolecular Rotation"], "Total_Cost": ["EUR 149 115"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["ROLEDS"], "Technology_Description": "\"We have discovered a new class of photo- and electroluminescent complexes which are suitable for incorporation into organic light emitting diodes (OLEDs) and which give up to 100% internal quantum yield. The new compounds are particularly suitable for the fabrication of OLEDs via cheap solution-processing techniques and have so far reached 27% external quantum efficiency, a record for any solution-processed device. The new complexes have a linear, rotationally flexible structure, and it is this rotation that allows 100% of the excitation energy to be harvested, by a new emission mechanism (\u201crotationally accessed spin-state inversion\u201d, RASI). OLEDs are widely used as flat-screen displays (TVs, smartphones), a multi-billion dollar market worldwide. The industry-leading emitters are based on complexes of iridium, one of the rarest elements on earth. Our emitters are compounds of copper, silver and gold, suitable as \u201cslot-in\u201d replacements of iridium. IPR is protected by two UK and one PCT World patent applications. The key discovery is that in certain types of coordination complexes based on carbene ligands the excited singlet state sinks below the excited triplet state during molecular rotation. To our knowledge this is the first realization of \"spin-state inverted\" materials, until now discussed only as a theoretical concept. The result is efficient, very fast light harvesting with highly desirable short (sub-microsecond) excitation lifetimes, leading to high display brightness (in prototypes 20 times brighter than a HD TV screen), with potential lighting applications.\"", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["754615"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["KARLSRUHER INSTITUT FUER TECHNOLOGIE", "KARLSRUHER INSTITUT FUER TECHNOLOGIE"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["A custom lock chip for compact NMR"], "Total_Cost": ["EUR 150 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["LockChip"], "Technology_Description": "Nuclear magnetic resonance is an important chemical analysis method, because of its inherent chemical specificity, its versatility to extract molecular information, and its absolute accuracy. The market has been dominated by large superconducting NMR magnets with price tags of many 100k \u20ac. The emergence of less expensive low field compact (tabletop and portable) NMR spectrometers, based on the use of permanent magnets, with price tags around a factor of 10 lower than superconducting magnets, brings a drastically lower cost-of-ownership, and the significantly lower need for external support, maintenance, and lack of liquid Helium, which is opening up new applications and huge new markets for NMR.", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["741728"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW", "KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW"], "EU_Contribution": ["EUR 147 500"], "Project_Title": ["Pharmacological safety testing in human adult stem cell-derived organoids"], "Total_Cost": ["EUR 147 500"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["TOXANOID"], "Technology_Description": "Toxicology and pharmacology assays are crucial pillars of modern drug development. They are essential to understand how tissues such as intestine and liver take up and degrade pharmaceutically active compounds. Due to the lack of suitable in vitro systems, these assays are carried out in experimental animals. This practice increases cost and development time but also creates significant ethical issues. ", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-04-01"], "Project_ID": ["737600"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["AALTO-KORKEAKOULUSAATIO", "AALTO-KORKEAKOULUSAATIO"], "EU_Contribution": ["EUR 149 858"], "Project_Title": ["Graphene Tunneling Accelerometer"], "Total_Cost": ["EUR 149 858"], "Country": ["Finland", "Finland"], "Project_ACR": ["GraTA"], "Technology_Description": "The commercialization of existing tunneling accelerometers is hindered by their complex fabrication and long-term instability. Based on our results and expertise from the currently running ERC project, we propose an innovative design using graphene as the game-changing material for tunneling accelerometers.", "To": ["2018-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["727542"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["UNIVERSITAET STUTTGART", "UNIVERSITAET STUTTGART"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["NMR-based Sensor Technology at Nanoscale"], "Total_Cost": ["EUR 150 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["NMRNTECH"], "Technology_Description": "Nuclear Magnetic Resonance (NMR) spectrometry is the most widely used method in the spectrometry market. With applications in various areas such as geo exploration, material quality control, drug development, and biomedical imaging, NMR provides rich spectroscopic information of the structure for material analyses. Therefore, for advancing human health and science, NMR spectrometry and also microfluidics are widely adopted technologies in studying biological processes and thus utilised in many biomedical applications. However, given its low sensitivity, the technique is only applicable to large specimens. This proof-of-concept project develops novel atomic-size defect centres in diamond, which are superior to the current state-of-the-art magnetic field sensors in terms of spatial resolution, sensitivity and rugged design. Initial tests with single sensing defects confirm estimates on the achievable spatial resolution down to a few nanometers and reduction of volumetric sensitivity by factor of 108 as compared to the existing technologies. Through achieving this level, we are able to bring the full functionality and integration of NMR, i.e. molecular specificity to micro analytics. Therefore, the improvement of NMR sensitivity and the development of nanoscale NMR imaging, promises revolutionary impacts on the areas of bioscience and spectrometry technology, which in turn enables new applications in areas such as nanotechnology and bioanalytics. In this project, we\u2019ll (1) demonstrate integration of a diamond-based NMR sensor into a microfluidic device and in magnetic storage system. To best prepare for the post-PoC commercialisation we\u2019ll (2) test the NMR device in real-life industrial application, i.e. in characterization of hard-dick\u2019s write-head. Moreover, we\u2019ll also (3) carry out pre-commercialisation and networking activities, and (4) plan for the commercialisation of the novel NMR microfluidic sensor technology.", "To": ["2018-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["727575"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["UNIVERSITEIT LEIDEN", "UNIVERSITEIT LEIDEN"], "EU_Contribution": ["EUR 1 999 342"], "Project_Title": ["Building an Evidence-Base for Reducing Gender Bias in Educational Pathways"], "Total_Cost": ["EUR 1 999 342"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["GirlsInScience"], "Technology_Description": "In 2012, the European Commission launched the campaign Science: It\u2019s a girl thing!, aimed at encouraging women to choose research careers, as they are sorely underrepresented in science, technology, engineering, and mathematics (STEM). Given that gender disparities in aptitude for specific fields are generally very small, highly gendered skewness in educational choices suggest pathways dictated by stereotypes rather than abilities, leaving valuable STEM talents unused.", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["726141"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["Biologicke centrum AV CR, v. v. i.", "Biologicke centrum AV CR, v. v. i."], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Insect Photoperiodic Timer"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Czech Republic", "Czech Republic"], "Project_ACR": ["InPhoTime"], "Technology_Description": "Daylength measuring devices such as the photoperiodic timer enable animals to anticipate and thus survive adverse seasons. This ability has contributed to the great success of insects living in temperate regions. Yet the basis of photoperiodic sensing remains elusive, because of the lack of suitable genetic models expressing photoperiod-dependent seasonal phenotypes. We have developed the linden bug, Pyrrhocoris apterus, into a genetically tractable model with a robust, photoperiod-dependent reproductive arrest (diapause). With the available tools, this insect has become ideal for deciphering the regulation of seasonality. The project has 3 clear and ambitious objectives: 1). Our goal is to define the molecular and anatomical bases of the photoperiodic timer. To achieve this, we propose to identify photoperiodic timer genes, genes regulating input to the timer, and early output markers, through an RNA interference screen(s). To define the molecular mechanism of the timer, we will employ genome editing to precisely alter properties of the key players. 2). Next, we will combine techniques of neuronal backfilling, in-vivo fluorescent reporters, and microsurgery to define the photoperiodic timer anatomically and to examine its spatial relationship to the circadian clock in the insect brain. 3). We will exploit the great natural geographic variability of photoperiodic timing in P. apterus to explore its genetic basis. Genetic variants correlating with phenotypic differences will be causally tested by genome editing within the original genetic backgrounds. Both the established and the innovative strategies provide a complementary approach to the first molecular characterization of the seasonal photoperiodic timer in insects. The proposed research aspires to explain mechanisms underlying the critical physiological adaptation to changing seasons. Deciphering mechanisms underpinning widespread adaptation might bring general implications for environment-friendly pest control.", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Czech Republic"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-04-01"], "Project_ID": ["726049"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["JOHN INNES CENTRE", "JOHN INNES CENTRE"], "EU_Contribution": ["EUR 2 162 500"], "Project_Title": ["The role of the symplast in host-pathogen interactions \u2013 how does the symplastic, intercellular exchange of molecules regulate the outcomes of defence and infection?"], "Total_Cost": ["EUR 2 162 500"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["INTERCELLAR"], "Technology_Description": "Cell-to-cell communication is fundamental to multicellular organisms. The exchange of information and resources between cells and tissues enables co-ordination of responses to environmental and developmental signals. In plants, the cytoplasm of adjacent cells is connected by plasma membrane-line pores called plasmodesmata (PD) that cross the cell wall, generating cytoplasmic continuity between cells and tissues. This interconnected cytoplasm is termed the symplast and is unique to plants. In plants, growing evidence suggests that innate immune responses rely on regulation of symplastic connectivity. My group previously discovered that regulation of PD (whether they are open or closed) is critical for immune responses. Further, we have shown that pathogens suppress host regulation of PD in an effort to maintain symplastic continuity between cells. We don\u2019t know why the host regulates the symplast during defence: while data suggests that different defence responses might differently exploit the symplast, we don\u2019t understand how the symplast defines the success of a response. Similarly, we don\u2019t know how a pathogen benefits from maintaining connectivity with surrounding host cells \u2013 is this to allow the movement of molecules to suppress defence, or is it to optimise access to host resources? This programme will investigate the question of how the symplast contributes to defence and infection strategies. We aim to understand how these strategies play out in an infection context. We will use experimental and computational approaches to generate models that allow us to predict the outcome of infection upon the basis of symplastic processes and PD regulation. Ultimately, this will create a framework for novel strategies to enhance pathogen resistance.", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-06-01"], "Project_ID": ["725459"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["KARLSRUHER INSTITUT FUER TECHNOLOGIE", "KARLSRUHER INSTITUT FUER TECHNOLOGIE"], "EU_Contribution": ["EUR 1 975 813,75"], "Project_Title": ["Preparing Cryptography for Modern Applications"], "Total_Cost": ["EUR 1 975 813,75"], "Country": ["Germany", "Germany"], "Project_ACR": ["PREP-CRYPTO"], "Technology_Description": "\"Cryptography currently faces fundamentally new challenges. Modern applications like Big Data or Cloud Computing require cryptographic methods that go far beyond secure communication. Such cryptographic methods have only been invented in recent years: namely, since 2009, several unexpected and game-changing *new cryptographic building blocks* have been introduced. Most prominently, constructions of fully homomorphic encryption, code obfuscation, and multilinear maps have been proposed. These constructions have opened the door to applications that were previously believed unattainable, such as the secure outsourcing of computations.", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["724307"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 596 500"], "Project_Title": ["Planetary Interiors Constrained by Key Laboratory Experiments"], "Total_Cost": ["EUR 1 596 500"], "Country": ["France", "France"], "Project_ACR": ["PICKLE"], "Technology_Description": "The knowledge of interiors of rocky planets of our solar system (Mercury, Venus, Earth and Mars) is important for understanding their formation, present state, and evolution. The comprehension of differences and similarities in the internal constitution and processes will shed a new light on the origin and evolution of the solar system.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-10-01"], "Project_ID": ["724690"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON", "UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 1 999 806"], "Project_Title": ["Carbon \u2013 Ice Composite Materials: Water Structure and Dynamics at the Carbon Interface"], "Total_Cost": ["EUR 1 999 806"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["CARBONICE"], "Technology_Description": "Carbon and water in its various states of matter make up a substantial proportion of our Universe. The two materials are highly dissimilar with respect to their chemical and physical properties. Elemental carbon is even often referred to as a hydrophobic, \u2018water-hating\u2019 material. Yet, the two materials often coexist and critical processes take place at the interface between these unlike chemical species. This includes the hydration shells of hydrophobic moieties in biomolecules, clathrate hydrate materials where water molecules crystallise around hydrophobic guest species as well as icy comets which are often black due to the presence of carbon at their surfaces.", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["725271"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE", "INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE"], "EU_Contribution": ["EUR 1 999 125"], "Project_Title": ["Ribosome inhibition by nascent or antimicrobial peptides"], "Total_Cost": ["EUR 1 999 125"], "Country": ["France", "France"], "Project_ACR": ["NascenTomiX"], "Technology_Description": "During the translation of genetic information into protein by the ribosome, nascent peptides occasionally inhibit their own synthesis by interacting with the exit tunnel of the large ribosomal subunit. Known as nascent chain-mediated translational arrest, this process depends primarily upon the amino acid sequence of the arrest peptide. However, it can also rely upon the sensing of a low molecular weight ligand by the ribosome nascent chain complex, explaining its use for metabolite-dependent gene regulation in both bacteria and eukaryotes. Biochemical and structural studies of arrest peptides have yielded key insights into their mode of action, but their ability to sense different types of small molecules, their impact as regulators of gene expression in nature and the precise molecular details behind the arrest process are still largely unexplored.", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-06-01"], "Project_ID": ["724040"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 871 250"], "Project_Title": ["Shaping a European Scientific Scene : Alfonsine Astronomy"], "Total_Cost": ["EUR 1 871 250"], "Country": ["France", "France"], "Project_ACR": ["ALFA"], "Technology_Description": "Alfonsine astronomy is arguably among the first European scientific achievements. It shaped a scene for actors like Regiomontanus or Copernicus. There is however little detailed historical analysis encompassing its development in its full breadth. ALFA addresses this issue by studying tables, instruments, mathematical and theoretical texts in a methodologically innovative way relying on approaches from the history of manuscript cultures, history of mathematics, and history of astronomy.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["723085"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITY OF LIMERICK", "UNIVERSITY OF LIMERICK"], "EU_Contribution": ["EUR 1 499 043,75"], "Project_Title": ["Solar Energy Conversion without Solid State Architectures: Pushing the Boundaries of Photoconversion Efficiencies at Self-healing Photosensitiser Functionalised Soft Interfaces"], "Total_Cost": ["EUR 1 499 043,75"], "Country": ["Ireland", "Ireland"], "Project_ACR": ["SOFT-PHOTOCONVERSION"], "Technology_Description": "Innovations in solar energy conversion are required to meet humanity\u2019s growing energy demand, while reducing reliance on fossil fuels. All solar energy conversion devices harvest light and then separate photoproducts, minimising recombination. Normally charge separation takes place at the surface of nanostructured electrodes, often covered with photosensitiser molecules such as in dye-sensitised solar cells; DSSCs. However, the use solid state architectures made from inorganic materials leads to high processing costs, occasionally the use of toxic materials and an inability to generate a large and significant source of energy due to manufacturing limitations. An alternative is to effect charge separation at electrically polarised soft (immiscible water-oil) interfaces capable of driving charge transfer reactions and easily \u201cdye-sensitised\u201d. Photoproducts can be separated on either side of the soft interface based on their hydrophobicity or hydrophilicity, minimising recombination. SOFT-PHOTOCONVERSION will explore if photoconversion efficiencies at soft interfaces can be improved to become competitive with current photoelectrochemical systems, such as DSSCs. To achieve this goal innovative soft interface functionalisation strategies will be designed. To implement these strategies an integrated platform technology consisting of (photo)electrochemical, spectroscopic, microscopic and surface tension measurement techniques will be developed. This multi-disciplinary approach will allow precise monitoring of morphological changes in photoactive films that enhance activity in terms of optimal kinetics of photoinduced charge transfer. An unprecedented level of electrochemical control over photosensitiser assembly at soft interfaces will be attained, generating photoactive films with unique photophysical properties. Fundamental insights gained may potentially facilitate the emergence of new class of solar conversion devices non-reliant on solid state architectures.", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["716792"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["ALBERT-LUDWIGS-UNIVERSITAET FREIBURG", "ALBERT-LUDWIGS-UNIVERSITAET FREIBURG"], "EU_Contribution": ["EUR 1 499 219"], "Project_Title": ["A Flexible Platform for the Application of SAM-dependent enzymes"], "Total_Cost": ["EUR 1 499 219"], "Country": ["Germany", "Germany"], "Project_ACR": ["AppSAM"], "Technology_Description": "AppSAM will unlock the synthetic capability of S-adenosyl\u00acmethionine (SAM)-dependent methyltransferases and radical SAM enzymes for application in environmentally friendly and fully sustainable reactions. The biotechnological application of these enzymes will provide access to chemo-, regio- and stereoselective methylations and alkylations, as well as to a wide range of complex rearrangement reactions that are currently not possible through traditional approaches. Methylation reactions are of particular interest due to their importance in epigenetics, cancer metabolism and the development of novel pharmaceuticals. As chemical methylation methods often involve toxic compounds and rarely exhibit the desired selectivity and specificity, there is an urgent need for new, environmentally friendly methodologies. ", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["716966"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["THE HEBREW UNIVERSITY OF JERUSALEM", "THE HEBREW UNIVERSITY OF JERUSALEM"], "EU_Contribution": ["EUR 1 867 181"], "Project_Title": ["A regional history of medicine in the modern Middle East, 1830-1960"], "Total_Cost": ["EUR 1 867 181"], "Country": ["Israel", "Israel"], "Project_ACR": ["Mideast Med"], "Technology_Description": "The purpose of this project is to write a long-term regional history of medicine in the Middle East and North Africa from a transnational and multi-layered perspective. A regional approach will enable tracing both global influences and local specificities, while a long-term perspective (1830-1960) will allow tracing continuity and change from the late Ottoman Middle East through the colonial to the post-colonial periods. Combining archival and published sources in Arabic, French, English, Hebrew, English, German and Ottoman Turkish, it will offer a unique perspective into the formation of the modern Middle East.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["723718"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["TECHNISCHE UNIVERSITEIT DELFT", "TECHNISCHE UNIVERSITEIT DELFT"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Origins of Collective Motion in Active Biofluids"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["ActiveBioFluids"], "Technology_Description": "The emergence of coherent behaviour is ubiquitous in the natural world and has long captivated biologists and physicists alike. One area of growing interest is the collective motion and synchronization arising within and between simple motile organisms. My goal is to develop and use a novel experimental approach to unravel the origins of spontaneous coherent motion in three model systems of biofluids: (1) the synchronization of the two flagella of green algae Chlamydomonas Rheinhardtii, (2) the metachronal wave in the cilia of protist Paramecium and (3) the collective motion of swimming microorganisms in active suspensions. Understanding the mechanisms leading to collective motion is of tremendous importance because it is crucial to many biological processes such as mechanical signal transduction, embryonic development and biofilm formation.", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["716712"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["UNIVERSITY OF DUNDEE", "UNIVERSITY OF DUNDEE"], "EU_Contribution": ["EUR 1 444 081"], "Project_Title": ["IMPACT OF DNA REPLICATION ON EPIGENETICS"], "Total_Cost": ["EUR 1 444 081"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["IDRE"], "Technology_Description": "During lineage propagation, cells must duplicate their genetic and epigenetic information to maintain cell identity. However, the mechanisms underlying the maintenance of epigenetic information in dividing cells remain largely unknown.", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["715127"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["UNIVERSITE DE LAUSANNE", "UNIVERSITE DE LAUSANNE"], "EU_Contribution": ["EUR 1 499 966"], "Project_Title": ["Plant cell wall communication and remodelling: the wall watchers."], "Total_Cost": ["EUR 1 499 966"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["WallWatchers"], "Technology_Description": "Plants, just like animals are highly developed multicellular organisms. In contrast to animal cells however, plant cells are surrounded by a rigid, carbohydrate-rich extracellular layer, the cell wall. This cell wall provides plants with mechanic support and a dynamic chemical signalling and metabolic environment. To allow for cell expansion, cell division, coordinated tissue growth and interactions with the environment, the cell wall status constantly needs to be sensed and modified. How plant cells perceive and signal their cell wall status is poorly understood. Here, I propose an integrated approach to uncover ligands for cell wall sensing receptors as well as their downstream signalling components. Specifically, my project aims to identify the ligands for two genetically validated cell wall receptor families, using a chemical biology approach. Next, we will analyse and validate the mode of ligand-receptor interaction by combining protein X-ray crystallography, quantitative biochemistry and reverse genetics in Arabidopsis. A detailed ligand-binding and receptor activation mechanism will allow us to specifically interfere with cell wall receptor function in vivo, and to assess their biological relevance for cell wall structure and its chemical properties. Using atomic force microscopy, we will then test if the receptors are distributed uniformly at the membrane or whether they are arranged in complex 'sensosomes'. Finally, we will characterize if plant cell wall receptors can directly act as mechanosensors. With defined receptor-ligand pairs and clear phenotypes at hand, we will try to uncover downstream signalling components for plant cell wall receptors and to validate our atomic models in planta. My ultimate goal would be to design and test cell wall receptor agonists and antagonists, which will represent powerful tools to alter cell wall homoeostasis in Arabidopsis, and potentially in crops.", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["716358"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON", "UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Peri-Ocularly Navigated Exteroceptive Snake Robot for Novel Retinal Interventions"], "Total_Cost": ["EUR 1 500 000"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["PIONEER"], "Technology_Description": "Intraocular treatments require manipulation of structures with dimensions comparable to hand tremor. The demanded dexterity, coupled with reduced haptic and depth perception, calls for robotic assistance. ", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["714562"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["UNIVERSITAT POLITECNICA DE CATALUNYA", "UNIVERSITAT POLITECNICA DE CATALUNYA"], "EU_Contribution": ["EUR 1 499 887"], "Project_Title": ["Atmospheric Pressure plAsma meets biomaterials for bone Cancer HEaling"], "Total_Cost": ["EUR 1 499 887"], "Country": ["Spain", "Spain"], "Project_ACR": ["APACHE"], "Technology_Description": "Cold atmospheric pressure plasmas (APP) have been reported to selectively kill cancer cells without damaging the surrounding tissues. Studies have been conducted on a variety of cancer types but to the best of our knowledge not on any kind of bone cancer. Treatment options for bone cancer include surgery, chemotherapy, etc. and may involve the use of bone grafting biomaterials to replace the surgically removed bone.", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["714793"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["CRANFIELD UNIVERSITY", "CRANFIELD UNIVERSITY"], "EU_Contribution": ["EUR 1 499 655,89"], "Project_Title": ["Sustainable Chemical Alternatives for Re-use in the Circular Economy"], "Total_Cost": ["EUR 1 499 655,89"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["SCARCE"], "Technology_Description": "This proposal seeks to develop a novel non-invasive, real-time direct observation methodology to provide new knowledge on the mechanisms underpinning crystal growth and harvesting within membrane crystallisation reactor technology. Crystallisation represents one of the most important separation processes in the chemical industry and will play a critical role in the circular economy through enabling the recovery of resources from wastewater to yield an array of sustainable low cost chemicals for use in European industries. Existing crystallisation reactor designs suffer from imperfect mixing and inhomogeneous solvent removal which makes control of crystal quality and consistency problematic and can limit application of the final product. ", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["714080"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["EIDGENOESSISCHE ANSTALT FUER WASSERVERSORGUNG ABWASSERREINIGUNG UND GEWAESSERSCHUTZ"], "EU_Contribution": ["EUR 175 419,60"], "Project_Title": ["Spatial and temporal biotransformation of micropollutants in a lake ecosystem"], "Total_Cost": ["EUR 175 419,60"], "Country": ["Switzerland"], "Project_ACR": ["LakeMP"], "Technology_Description": "Freshwaters are increasingly contaminated with a variety of pesticides, pharmaceuticals, personal care product ingredients and industrial chemicals referred as \u201cmicropollutants\u201d (MPs). Most of these MPs are poorly retained by wastewater treatment plants, and thus are released into natural water bodies, where they can travel all the way to the raw water of drinking water treatment plants. Very little information is currently available on the persistence and transformation of MPs in lake ecosystems. This project aims to investigate the fate of twelve MPs in lake Greifensee in Switzerland by measuring their transformation rates at different depths and seasons. To this end, lake water will be sampled at different depths in Lake Greifensee, and natural microbial communities (bacteria and phytoplankton) will be exposed to a mixture of different MPs using semipermeable plastic bags that will be redeployed to their original depth. The bags will let gases, salts and ions be exchanged with the outside environment, but will retain MPs and microorganisms inside the bag. At regular intervals, MP concentrations and their transformation products in the bags will be determined in order to calculate biotransformation rates of MPs at different depths of the lake. Phytoplankton and bacteria communities will be analyzed to assess the role of microorganisms in MP transformation using cutting edge \u201comics\u201d methods such as metagenomics. This project will be unique in that it actually quantitatively describes the extent of MP biotransformation in situ, and thus eliminates many of the uncertainties involved in estimating in-field biodegradation based on laboratory experiments. It will also bring more in-depth knowledge on the drivers of biotransformation, whether they are of bacteria or phytoplankton origin. This project will hence foster improved risk assessment and management of the release of contaminants into the environment.", "To": ["2019-09-04, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Research Organisations"], "From": ["2017-09-05"], "Project_ID": ["750700"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE"], "EU_Contribution": ["EUR 175 419,60"], "Project_Title": ["Affordable DNA Mapping using Solidstate-Nanopores"], "Total_Cost": ["EUR 175 419,60"], "Country": ["Switzerland"], "Project_ACR": ["DNA NANO MAP"], "Technology_Description": "DNA analysis will become an important clinical tool in identification the composition of microbial species living in the gut. The most dominant technique at the time is based on PCR amplification of the 16s rDNA gene and subsequent sequencing of the variable region in the gene. This method however is limited in the amount of detail it provides and is notoriously susceptible to primer bias. Furthermore, due to the requirement of a PCR machine and sequencer the technique is too expensive and time consuming for a clinical setting. ", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["751121"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF SURREY"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Ageing Diversity: LGBT* \u2013 Housing and Long-term Care"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["AgedLGBT"], "Technology_Description": "Existing studies about Lesbian, Gay, Bisexual, and Trans* (LGBT*) people have shown that those aged over fifty years of age (hereafter LGBT* seniors), are more likely to be childless, single and to live alone than their heterosexual peers. Housing, either with or without care, is a principal area of concern to LGBT* seniors, yet few studies exist in Europe that have directly addressed this topic. AgedLGBT* will make a significant contribution to knowledge about LGBT* seniors and housing by comparing and synthesizing the work of research projects conducted in Germany and the UK. It therefore represents a unique and valuable opportunity to understand this issue on a broader, international scale and significantly adds to the value and usefulness of European social science about LGBT* ageing. AgedLGBT* will use the data of two nationally unique research projects of the Alice Salomon University of Applied Sciences Berlin (D) and one conducted by the University of Surrey (UK) integrating these and adding to them across four interrelated work packages (WP): AgedLGBT* will compare and synthesize data from the research projects GLESA & GLEPA (D) and SAFE Housing (UK) to investigate similarities and variations about LGBT* seniors and housing (WP I). WP II comprises interviews with key experts, dealing with excluded minorities (such as LGBT* elders with lower income as well as trans* and intersexual seniors). A secondment at Stonewall Housing, UK, will support the realization of the interviews and strengthen the social work experience of the researcher. A social simulation model (WP III) for the cohorts of future LGBT* elders based on the analysis of data in WP I will provide new ways to hypothesize and understand the issue. Also the training in Agent-Based Modelling will be crucial for the researcher\u2019s prospects. A symposium with experts (WP IV) and practitioners will be organised as a feedback platform with practical relevance and for looking beyond a LGBT* perspective.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["749760"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITEIT UTRECHT"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["Exploiting in vitro evolution of macrocyclic glycopeptides to explore selectin interactions"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["GlycoPeptides"], "Technology_Description": "Many important biological processes involve binding of proteins to carbohydrates, including the recruitment of immune cells to tissues by proteins called selectins. The core binding requirement of all three types of selectins is a four sugar unit called the Sialyl LewisX epitope. However, affinity for this epitope alone is low. Further requirements for binding of selectins to their glycoprotein ligands include other carbohydrate and protein moieties, as well as sulfation of the carbohydrate or tyrosines. Open questions include what is necessary and sufficient for tight binding to each selectin, what sorts of ligands can bind to all selectins, and how the binding requirements can be presented on a synthetic scaffold. Answers to these questions will lead to a better understanding of the selectins, tools for future biological studies, and hopefully new medications for the many immune disease processes in which their abnormal functioning has been implicated.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["746631"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSIDAD DE OVIEDO"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Vancomycin resistance regulation in the antibiotic-producers streptomycetes"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["Vanrestrep"], "Technology_Description": "Antimicrobial resistance is a critical health issue today. Important pathogens have become resistant to many or all available antibiotics and limited new antibiotics are in the pipeline. Vancomycin is used as a \u2018last resort\u2019 antibiotic treatment for many bacterial infections, but worryingly vancomycin resistance (VR) has spread to major hospital-acquired pathogens such as Enterococcus faecium and Staphylococcus aureus. Most pathogen VR gene clusters likely came from actinomycetes, the natural producers of glycopeptides and most other antibiotics of natural origin. Induction of VR in the model actinomycete Streptomyces coelicolor is highly influenced by nutritional conditions, in particular by the phosphate (Pi) concentration in the medium. My previous work has shown that VR in S. coelicolor is blocked with Pi concentrations above 0.2%; suggesting a key role of this nutrient in VR repression. Furthermore, I have isolated a mutant strain (SCO2594::aac(3)IV) lacking this Pi control over VR. This mutant has cell wall synthesis defects and up-regulates a putative small non-coding RNA (sRNA) located in the promoter region of the vanSR regulatory genes. This project aims to understand the mechanisms of Pi regulation of the S. coelicolor van cluster, and to expand this study to other nutrients that may also control VR. A main focus is on the role of sRNAs in the regulation, as they offer potential novel targets for future clinical exploitation such as \u201cantisense RNA therapy\u201d. The work also aims to understand the role of SCO2594 in VR and to identify new players involved in the process. The proposed project represents an excellent opportunity for the researcher to develop new skills whilst helping to ramp up the development of new antimicrobial platforms in the Salas lab.", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["740080"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["HOGSKOLEN I BODO"], "EU_Contribution": ["EUR 231 642,20"], "Project_Title": ["Metabolism of Novel Strains of Arctic Algae"], "Total_Cost": ["EUR 231 642,20"], "Country": ["Norway"], "Project_ACR": ["MONSTAA"], "Technology_Description": "Due to increasing environmental and economic pressures, there is a need to develop more efficient and sustainable food, feed and fuel production systems. Microalgae have substantial potential as single-cell molecular factories for producing high quality lipids, proteins and carbohydrates. They are capable of faster growth rates than crop plants and synthesize valuable metabolites that do not occur naturally in other primary producers. However, a major bottleneck that currently limits widespread microalgae production are the low yields achieved by commercial strains in cold climates. This project will develop new varieties of microalgae isolated from Arctic and Antarctic environments for applied bioprocesses. The work will include studying the metabolism of novel microalgae in low temperature bioreactors using functional genomics. The researcher will spend the outgoing phase at an established microalgae metabolism laboratory in the USA, where complete and very high quality training will be given in cutting-edge Next Generation Sequencing (NGS) technology. Genomic and transcriptomic work will be paired with metabolomics to give new insights into the regulation of metabolism in non-model microalgae species. The research will also include integrating data together into metabolic flux model frameworks. The major research outcomes will be (1) Genome-scale characterization of brand-new varieties of microalgae (2) Development of novel microalgae bioprocesses for high yields of lipids, proteins and carbohydrates in cold climates (3) Predictive metabolic models for maximizing yields of products of interest in non-model varieties of microalgae. In addition, comprehensive work and dissemination plans are presented that will target scientists, industry and the public.", "To": ["2020-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["749910"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF LEEDS"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Scaffold hybridization approach targeting PPIs"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SHAPPI"], "Technology_Description": "Protein-protein interactions (PPIs) control all cellular processes relevant to health and disease, hence an outstanding challenge in chemical biology is to develop generic approaches for PPI inhibition. Such inhibitors (or chemical probes) represent unique tools to understand biological processes and starting points for drug discovery, for treatment of multiple illnesses for which effective treatments don\u2019t currently exist e.g. cancer. ", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["749012"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["STOCKHOLMS UNIVERSITET", "STOCKHOLMS UNIVERSITET"], "EU_Contribution": ["EUR 1 968 375"], "Project_Title": ["High-valent protein-coordinated catalytic metal sites: Geometric and Electronic ARchitecture"], "Total_Cost": ["EUR 1 968 375"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["HIGH-GEAR"], "Technology_Description": "It is estimated that almost half of all enzymes utilize metal cofactors for their function, for example the respiratory complexes and the oxygen-evolving photosystem II, the most fundamental requirements for aerobic life as we know it. If we could mimic nature\u2019s use of metals for harvesting sunlight, energy conversion and chemical synthesis it would eliminate the need for fossil fuels and greatly increase the possibilities of chemical industry while reducing the environmental impact. Achieving this type of chemistry is an outstanding testament to evolution and understanding it is a glaring challenge to mankind.", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["724394"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["STOCKHOLMS UNIVERSITET", "STOCKHOLMS UNIVERSITET"], "EU_Contribution": ["EUR 1 487 245"], "Project_Title": ["Automatized Catalysis and Single-Carbon Insertion"], "Total_Cost": ["EUR 1 487 245"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["single-C"], "Technology_Description": "This project is aimed at accelerating the synthesis of important organic molecules through key enabling technologies towards automatized catalysis and single-carbon insertion reactions. Transferring the simplest carbon units to organic molecules has the potential to change the way we approach synthesis planning through new asymmetric skeletal homologations and rearrangements of simple raw materials, for which only long workarounds exist now. These methods can reduce to half the manipulations required to access relevant medicines, organocatalysts, ligands, bio-molecular tools and photovoltaic devices. They target unreactive functions to introduce fundamental one-carbon units (CO or C) that are present in virtually any organic compound. New powerful reagents that resemble these basic single-carbon units in excited electronic configurations are to be developed for this purpose. The new catalytic methods needed are based on the solid grounds of carbene-transfer reactions and the recent advances of my group in the development of new homogeneous catalysts. Moreover, a new catalyst platform will be developed to complement our existing portfolio for success in the challenging processes targeted in this proposal. We aim to pioneer a fully automatized workflow for research in catalysis that devoid the synthesis of organic ligands replacing them by combinatorial assemblies built in situ from un-structured simple molecules. The new reactions arising from these new catalysts and reagents will expedite the valorization of raw materials (such as carbonyls, olefins and hydrocarbons) into important chiral molecules in a single transformation. This bold aim is a priority of the European Commission for the coming years as it will save time, protect the environment and reduce cost at once. Thus, these innovative technologies have the potential of transforming the research workflow in homogeneous catalysis and the logics of retrosynthesis of organic molecules at a fundamental level.", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["714737"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["BEN-GURION UNIVERSITY OF THE NEGEV", "BEN-GURION UNIVERSITY OF THE NEGEV"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Hierarchical Inorganic Nanomaterials as Next Generation Catalysts and Filters"], "Total_Cost": ["EUR 150 000"], "Country": ["Israel", "Israel"], "Project_ACR": ["3Dmaterials4Energy"], "Technology_Description": "In the coming few decades, two major global grand challenges will continue to attract the attention of scientists and engineers in academia and industry: achieving clean water and clean energy. This PoC establishes the development of two prototypes, water oxidation catalyst and water purification filter, by creating inexpensive, abundant and versatile hierarchical structures of inorganic nanomaterials (HSINs). ", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-03-01"], "Project_ID": ["755301"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["UNIVERSIDAD POMPEU FABRA", "UNIVERSIDAD POMPEU FABRA"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["A Mnemonic system based on stimulation-free Neuroimaging"], "Total_Cost": ["EUR 150 000"], "Country": ["Spain", "Spain"], "Project_ACR": ["MNeuronic"], "Technology_Description": "This project\u2019s aim is the commercialization of a neurotechnology device, MNeuronic, that helps its users to improve their memory retention. MNeuronic can be used in cognitive rehabilitation on patients with mild to moderate decline in memory function as well as by healthy users, as a cognitive training method at home. The system will be mounted on wearable, relatively affordable hardware. Its core technology is grounded on principles and ideas developed in my current ERC-StG project on attention and perception. In particular, MNeuronic capitalizes on the natural fluctuations of neural excitability in the human brain using real-time phase prediction. This confers two important commercial strengths. One is efficiency, because MNeuronic anticipates upcoming optimal brain states before they occur, rather than reacting to past states. Second, MNeuronic affords unprecedented levels of temporal precision. Besides its direct application for memory enhancement, the core principles that ground MNeuronic are transferable to further applications in neurotechnology for learning/education, cognitive training, recreation (neurogaming) or, wellness. This opens a second commercialization route that reaches out to other neurotechnology companies, which will also be exploited in this project. The software implementing MNeuronic (real-time analysis filters and prediction algorithms) will be protected under a dual license that will allow us to combine a proprietary license offered to client companies, and open-licenses addressed to non-profit research and education organizations. Because MNeuronic offers non-invasive, stimulation-free solutions, it will appeal as a less aggressive rehabilitation support tool to be marketed in clinical contexts. In addition, with an effort toward affordable costs and wearable hardware, we intend to cater non-clinical, home-users. Home-use neurotechnology is becoming an increasingly important emerging market because its potential size and growth rate.", "To": ["2018-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["727595"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["UNIVERSIDAD POMPEU FABRA", "UNIVERSIDAD POMPEU FABRA"], "EU_Contribution": ["EUR 1 499 805"], "Project_Title": ["A distributional MOdel of Reference to Entities"], "Total_Cost": ["EUR 1 499 805"], "Country": ["Spain", "Spain"], "Project_ACR": ["AMORE"], "Technology_Description": "\"When I asked my seven-year-old daughter \"Who is the boy in your class who was also new in school last year, like you?\", she instantly replied \"Daniel\", using the descriptive content in my utterance to identify an entity in the real world and refer to it. The ability to use language to refer to reality is crucial for humans, and yet it is very difficult to model. AMORE breaks new ground in Computational Linguistics, Linguistics, and Artificial Intelligence by developing a model of linguistic reference to entities implemented as a computational system that can learn its own representations from data.", "To": ["2022-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-02-01"], "Project_ID": ["715154"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["TECHNISCHE UNIVERSITAET GRAZ", "TECHNISCHE UNIVERSITAET GRAZ", "JOANNEUM RESEARCH FORSCHUNGSGESELLSCHAFT MBH"], "EU_Contribution": ["EUR 1 499 108,76"], "Project_Title": ["Smart Core/shell nanorod arrays for artificial skin"], "Total_Cost": ["EUR 1 499 108,76"], "Country": ["Austria", "Austria", "Austria"], "Project_ACR": ["SmartCore"], "Technology_Description": "The replication of the circle of information coming from the environment, to the skin, to an action mediated by the brain, requires a lot of advances in smart technology and materials development. Embedding sensors in smart architectures that record the stimulus from the environment and transform it into action is the objective of artificial skins. At the moment, different sensors have to be implemented in the artificial skin matrix for each stimulus. ", "To": ["2021-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2016-12-01"], "Project_ID": ["715403"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["THE UNIVERSITY OF SHEFFIELD", "STOCKHOLMS UNIVERSITET", "UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA"], "EU_Contribution": ["EUR 1 569 640,32"], "Project_Title": ["Catalytic Methods for Sustainable Synthesis. A Merged Experimental and Computational Approach"], "Total_Cost": ["EUR 1 569 640,32"], "Country": ["United Kingdom", "Sweden", "Spain"], "Project_ACR": ["CATMEC"], "Technology_Description": "CATMEC is a multi-partner European Joint Doctorate (EJD) Programme offering research training in state-of-the-art sustainable chemical synthesis, catalysis, computational chemistry and bioactive molecule design on both traditional and non-traditional (eg flow) platforms. This Doctoral Training Programme integrates complementary, interdisciplinary and intersectoral training and together with enhanced European mobility through planned secondments of researchers, will contribute to EU policy objectives in scientific training and degree assessment. The researchers will be supervised and mentored by internationally recognised experts and have access to state-of-the-art equipment. Hands-on training will be supplemented by formal training courses in relevant and related fields, and a wide variety of complementary training courses, workshops and seminars. The training of researchers will benefit from secondments to industrial partners, gaining exposure to commercial and complementary environments. Overall, it is anticipated that the CATMEC project will provide Early Stage Researchers (ESRs) with an outstanding training experience, through extensive technical and complementary skills development.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-EJD - European Joint Doctorates"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["721223"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["CONSIGLIO NAZIONALE DELLE RICERCHE", "IONFLY VACUUM AND PLASMA TECHNOLOGY SRL"], "EU_Contribution": ["EUR 100 000"], "Project_Title": ["Dielectric MicroSpacer Technology"], "Total_Cost": ["EUR 100 000"], "Country": ["Italy", "Italy"], "Project_ACR": ["DMS"], "Technology_Description": "Several technological applications need tools for keeping a stable micrometric distance between two surfaces. The requirements are more stringent if electrical insulation has to be guaranteed between the surfaces and even more if also thermal insulation has to be satisfied.", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-04-2016-2017 - FET Innovation Launchpad"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-04-01"], "Project_ID": ["754568"], "Call_for_Proposal": ["H2020-FETOPEN-4-2016-2017"]}, -{"Partners": ["UNIVERSITA DI PISA", "KUNGLIGA TEKNISKA HOEGSKOLAN", "UNIVERSIDAD POLITECNICA DE MADRID", "UGANDA INDUSTRIAL RESEARCH INSTITUTE", "KENYATTA UNIVERSITY", "TARTU ULIKOOL", "AGILEWORKS OU"], "EU_Contribution": ["EUR 992 250"], "Project_Title": ["Euro-African Open Biomedical Engineering e-Platform for Innovation through Education"], "Total_Cost": ["EUR 992 250"], "Country": ["Italy", "Sweden", "Spain", "Uganda", "Kenya", "Estonia", "Estonia"], "Project_ACR": ["UBORA"], "Technology_Description": "The project aims at creating an EU-Africa e-Infrastructure, UBORA, for open source co-design of new solutions to face the current and future healthcare challenges of both continents, by exploiting networking, knowledge on rapid prototyping of new ideas and sharing of safety criteria and performance data. The e-infrastructure will foster advances in education and the development of innovative solutions in Biomedical Engineering (BME), both of which are flywheels for European and African economies. It is conceived as a virtual platform for generating, exchanging, improving and implementing creative ideas in BME underpinned by a solid safety assessment framework. Besides the provision of resources with designs, blueprints and support on safety assessment and harmonisation, specific sections for needs identification, project management, repositories and fund raising are also foreseen. ", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["INFRASUPP-03-2016 - Support to policies and international cooperation for e-infrastructures"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["731053"], "Call_for_Proposal": ["H2020-INFRASUPP-2016-1"]}, -{"Partners": ["THE UNIVERSITY OF EDINBURGH"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Development of the new internally-heated diamond-anvil cell for planetary mineral physics: Application to high-pressure melting of H2O ice"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["NEWDIA4Planet"], "Technology_Description": "For the past few decades, diamond anvil cell (DAC) has been the most commonly used static high-pressure device to reproduce simultaneous high pressure (P) and temperature (T) conditions of deep planetary interiors. Laser-heated DAC achieved P-T conditions corresponding to the centre of the Earth. However, the laser heating system causes large temperature uncertainties (\u00b110%), which is critical when one tries to understand planetary interiors based on phase relations of the candidate materials. The major objective of this proposal is therefore, to develop a new heating system for the DAC which enables us to heat the sample stably and homogeneously. The new design will be based on so-called internally-heated DAC (IHDAC). In an existing IHDAC, a thin metallic heater which is the sample at the same time, provides homogeneous high temperature. One of the limitations of the existing system is that it is applicable only to the metallic sample. Therefore, (1) we aim to develop a micro-heater configuration which can heat any type of materials, e.g., silicate, oxide, and H2O. We plan to achieve the P-T condition of P = 200 GPa and T = 4000 K. Then (2) we will conduct high-pressure melting experiments on H2O ice. The melting temperature of H2O ice under pressure places important constraints on the structure of Ice Giants such as Uranus and Neptune. Previously reported melting temperatures of H2O show large discrepancies, one of the major reasons for which is that most of those studies were based on the laser heating with large temperature uncertainties. Our new IHDAC will offer incontrovertible melting data from homogeneous and stable heating, and therefore it has a great potential to solve the long-standing controversy of the existing melting temperatures. Our new IHDAC will be a conventional technique for the researches on the planetary interior for the next decade.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["753858"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF EDINBURGH"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Masculinities, Youth and Violence in the Moroccan Underclass: Young Men and Their Future Selves."], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["MoroccoMasculinities"], "Technology_Description": "Male juvenile delinquency as represented by self-styled tcharmils has been the focus of a moral panic in Morocco over the last years. The tcharmil subculture has gained visibility through a social-media propagated aesthetic that turns the stigma of social disqualification into a source of pride by extolling assertive masculinity, violence, and the transgression of social and religious norms. By adopting consumerist values that overlap with those of more privileged classes, and by frequenting the latter\u2019s urban spaces of leisure, the tcharmil blur social boundaries. The resulting anxieties among the privileged has resulted in public campaigns and police crackdown. MoroccoMasculinities examines the construction of the masculinities of disadvantaged young men in order to understand how gender, class, space and ethnicity intersect in juvenile moral and cultural formations in today\u2019s Morocco. On the one hand, studying the tcharmil subculture reveals how juvenile subjectivities are reshaped by the combined effect of urbanisation, the new media, and state policies interlinked with global systems of regulation such as neo-liberal reforms, restrictions on migratory movements, and the intensification of the struggle against the hashish economy. On the other hand, the study of state reactions to the same subculture allows to highlight changing patterns of criminalisation: the unprecedented emphasis on male delinquency possibly reflects a strategy of discursive de-politicisation of the threats to an established order faced with the challenges of the Arab Spring and its aftermaths.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["753562"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["INSTITUT VON KARMAN DE DYNAMIQUE DES FLUIDES", "KUNGLIGA TEKNISKA HOEGSKOLAN", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "INSTYTUT MASZYN PRZEPLYWOWYCH IM ROBERTA SZEWALSKIEGO POLSKIEJ AKADEMII NAUK - IMP PAN", "TECHNISCHE UNIVERSITEIT DELFT", "UNIVERSITY OF SOUTHAMPTON", "KATHOLIEKE UNIVERSITEIT LEUVEN", "ECOLE CENTRALE DE LYON", "NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA", "SIEMENS INDUSTRY SOFTWARE NV", "SIEMENS GAMESA RENEWABLE ENERGY AS", "CENTRE TECHNIQUE DES INDUSTRIES AERAULIQUES ET THERMIQUES"], "EU_Contribution": ["EUR 3 844 758,48"], "Project_Title": ["Smart mitigation of flow-induced acoustic radiation and transmission for reduced aircraft, surface transport, workplaces and wind energy noise"], "Total_Cost": ["EUR 3 844 758,48"], "Country": ["Belgium", "Sweden", "France", "Switzerland", "Poland", "Netherlands", "United Kingdom", "Belgium", "France", "Greece", "Belgium", "Denmark", "France"], "Project_ACR": ["SmartAnswer"], "Technology_Description": "A step change in our noise mitigation strategies is required in order to meet the environmental targets set for a number of sectors of activity affecting people through noise exposure. Besides being a hindrance to our daily life and subject to regulations, noise emission is also a competitive issue in today\u2019s global market. To address these issues, new technologies have been emerging recently, based on radically new concepts for flow and acoustic control, such as micro-electro-mechanical devices (MEMs), meta-materials, porous treatment of airframe surfaces, airfoil leading-edge or trailing-edge serrations, micro-jets, plasma actuation, \u2026 Some of these new ideas appear nowadays promising, but it now appears to this consortium that the development and maturation of novel noise reduction technologies is hindered by three main factors. The first factor is an insufficient understanding of the physical mechanisms responsible for the alteration of the flow or acoustic fields. In absence of a phenomenological understanding, modelling and optimization can hardly be successful. Secondly, tight constraints (safety, robustness, weight, maintainability, etc.) are imposed to any novel noise mitigation strategy trying to make its way to the full-scale industrial application. Thirdly, there is an insufficient knowledge about the possibilities that are nowadays offered by new materials and new manufacturing processes. With this project, we intend to setup a research and training platform, focused on innovative flow and noise control approaches, addressing the above shortcomings. It has the following objectives: i) fostering a training-through-research network of young researchers, who will investigate promising emerging technologies and will be trained with the inter-disciplinary skills required in an innovation process, and ii) bringing in a coordinated research environment industrial stakeholders from the aeronautical, automotive, wind turbine and cooling/ventilation sectors.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Belgium"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["722401"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET", "HELMHOLTZ-ZENTRUM FUER UMWELTFORSCHUNG GMBH - UFZ", "Masarykova univerzita", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "EIDGENOESSISCHES DEPARTEMENT FUER WIRTSCHAFT, BILDUNG UND FORSCHUNG", "PROFESSIONSHOJSKOLEN METROPOL", "EIDGENOESSISCHE ANSTALT FUER WASSERVERSORGUNG ABWASSERREINIGUNG UND GEWAESSERSCHUTZ", "HOFOR AS", "FERA SCIENCE LIMITED", "STOCKHOLMS UNIVERSITET"], "EU_Contribution": ["EUR 3 976 833,96"], "Project_Title": ["Natural Toxins and Drinking Water Quality - From Source to Tap"], "Total_Cost": ["EUR 3 976 833,96"], "Country": ["Denmark", "Germany", "Czech Republic", "Spain", "Switzerland", "Denmark", "Switzerland", "Denmark", "United Kingdom", "Sweden"], "Project_ACR": ["NaToxAq"], "Technology_Description": "Clean drinking water is crucial to human health and wellbeing. The ambition of the NaToxAq ETN network is to expand the research basis for EU\u2019s leading role in securing high quality drinking waters for its citizens. Focus is on natural toxins \u2013 a large group of emerging contaminants with unknown impact on drinking water resources. Both known toxins, like cyanotoxins, cyanogenic glucosides and terpenes and not yet explored toxins will be investigated. Twenty leading universities, research institutions, and water enterprises will pioneer the field through joint training of 15 ESRs investigating natural toxin emission via water reservoirs to water works and consumers. The natural toxin challenge is addressed by the concerted work of the ESRs within 4 scientific work packages comprising origin, distribution, fate and remediation. Priority toxins are selected using in silico approaches accompanied by novel non-targeted and targeted analyses to map natural toxins along vegetation and climatic gradients in Europe. Invasion of alien species, toxin emission, leaching and dissipation will be under strong influence of climate change. Data collected for toxin emission, properties and fate will be used to model effects of climate, land use, and design of remediation actions. Special attention will be paid to toxin removal at water works including development of new technologies tailored to remove natural toxins. The results will contribute to strengthening of European policies and regulation of drinking water, while new business opportunities within the fields of water supply and treatment, chemical monitoring and sensing, and the consulting sector will arise from academia-indstry collaborations. The urgency of the challenge, its eminent knowledge gaps, its multifaceted and multidisciplinary nature, and the need for scientific and public awareness to be communicated by ESRs in a balanced way makes the topic ideal for a European mobility and training network.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["722493"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["KATHOLIEKE UNIVERSITEIT LEUVEN"], "EU_Contribution": ["EUR 160 800"], "Project_Title": ["Accelerating Clinical Translation. Charting the Politics of Translation in the European Union"], "Total_Cost": ["EUR 160 800"], "Country": ["Belgium"], "Project_ACR": ["ACTrans"], "Technology_Description": "In the post\u2013genomic era, innovation policies in biomedicine are increasingly being driven by the notion that constant advancements in biological knowledge fail to materialize into tangible therapeutic outcomes. Discursively framed in terms of a \u201cgap\u201d between \u201cbench\u201d and \u201cbedside\u201d in need of urgent \u201cbridging\u201d, this representation of the shortcomings of biomedical innovation has propelled growing efforts tailored towards the clinical translation of research results. In the European Union, the acceleration of clinical translation has been positioned as a cornerstone of its innovation strategy, as attested by the launch of a host of translational policy initiatives and a vast array of regulatory reforms in the process of medicines approval.", "To": ["2020-01-21, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-22"], "Project_ID": ["753531"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE CATHOLIQUE DE LOUVAIN"], "EU_Contribution": ["EUR 172 800"], "Project_Title": ["Innovative sol-gel strategies for the production of homogeneous, hydrothermally stable, andporous mixed metal oxide catalysts for biomass conversion applications"], "Total_Cost": ["EUR 172 800"], "Country": ["Belgium"], "Project_ACR": ["NewCat4Bio"], "Technology_Description": "The project is focused on the preparation, characterization and application of (hydro)thermally stable, homogeneous, and porous metallosilicate catalysts. As a synthetic route we will apply non-hydrolytic sol-gel routes since they produce materials with high homogeneity and they allow the one-step functionalization of the oxides surface. We will focus and demonstrate our results primarily on the synthesis of alumosilicates, and then broaden the work to Zr-, Ti-, Nb-, and Ta-doped silicates. We will use advanced analytic techniques for the characterization of heterogeneous catalysts \u2013 infrared spectroscopy, solid state nuclear magnetic resonance, nitrogen and ammonia adsorption-desorption experiments, electron microscopy, powder x-ray diffraction, small angle x-ray scattering, and surface analytical techniques \u2013 time-of-flight secondary ion mass spectrometry and x-ray photoelectron spectroscopy. We will evaluate our materials as catalysts in alcohol dehydration. For this type of reaction it is desirable to have hydrothermally stable acidic material. Hydrothermal instability is usually the main drawback of mixed metal oxides. Therefore we will tune the hydrophobicity of prepared materials and their surfaces by introduction of various organic groups in order to improve their performances. We will focus on the control of the pore size distribution as well and prepare stable and homogeneous materials with large pores applicable in catalytic actions on bulky (bio)molecules. In such a way the project will establish fruitful cooperation between the two research groups \u2013 one focused primarily on the synthetic pathways to novel materials and the second focused on their application in heterogeneous catalysis. The fellow will learn new characterization techniques and catalytic testing under industrially-relevant conditions. He will work independently, attain new soft skills and will prepare for the establishing of new research group back in Brno.", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["751774"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Early Upper Palaeolithic personal ornaments and behavioural adaptations"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["EU-BEADS"], "Technology_Description": "EU-BEADS investigates symbolically mediated behaviour of Early Upper Palaeolithic modern humans through the study of personal ornaments. Specifically, EU-BEADS will focus on the Levantine region between 60,000 and 40,000 years ago. The goal is a better understanding of variation and standardisation in shell bead production and use, as well as establishing new criteria for identification of anthropic modifications of marine shell beads. To achieve this, EU-BEADS employs a range of state-of-the-art zooarchaeological and taphonomic methodologies in conjunction with newly learned analytical techniques namely finite element analysis, use-wear analysis and GIS. In addition, EU-BEADS aims to develop a new analytical method to improve quantification of human actions in the production of shell beadwork using geometrics morphometrics. The large shell bead collection of Ksar\u2019 Akil (Lebanon) will serve as a case study. The high quality, multidisciplinary research results will contribute significantly to our knowledge of Early Upper Palaeolithic behavioural adaptations and of modern human symbolically mediated behaviours in general.", "To": ["2018-09-27, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["656325"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITY OF SOUTHAMPTON"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Resilient steel frame against fire and seismic hazards"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ResFrameFireSeismic"], "Technology_Description": "Conventional seismic-resistant structures are designed to experience significant damage under moderate-to strong earthquakes and this results in socio-economic losses such as injuries, high repair costs and disruption of the building use or occupation. To address this issue, researchers have developed modern seismic-resilient frames that can avoid inelastic deformations (i.e. damage) in structural members. Fire is another type of loading, which can cause significant damage and collapse. Moreover, fire after strong earthquakes is also a highly probable catastrophic event as it has been seen after recent earthquakes (e.g. Indonesia 2009, Chile 2010). Despite the fact that the risk of fires is high after strong earthquakes, seismic resilient structural systems have not yet been studied against fire and fire after earthquake loading. This project will assess the behaviour of modern seismic-resilient self-centering post-tensioned steel frames against fire loading and will propose modifications of their structural details so that, apart from seismic resilience, fire robustness can be also achieved. The project aims to develop, for the first time, an innovative steel frame characterized by the unique combination of minimal damage seismic behaviour and robustness against fire and post-earthquake fire loading.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["751904"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KATHOLIEKE UNIVERSITEIT LEUVEN"], "EU_Contribution": ["EUR 160 800"], "Project_Title": ["Christian-Muslim families dealing with religious pluralism in everyday family lifeReligious reconstruction in religiously mixed marriages"], "Total_Cost": ["EUR 160 800"], "Country": ["Belgium"], "Project_ACR": ["ReMix"], "Technology_Description": "Mixed families are both the index and agent of social change: they exemplify the increase in migration flows and provide us with an opportunity to analyse the everyday processes related to Europe\u2019s growing pluralism. Quantitative studies demonstrate that interfaith marriages lead to higher divorce rates, suggesting that the latter are due to communication difficulties and disagreements caused by cultural differences between partners, as well as to hostility from families of origin, religious institutions and society at large. However, rather than being firmly and empirically established, these concepts remain mere assumptions and, as such, also conceal the ways in which those involved actively and reflexively deal with these dynamics to prevent damage to their relationship. Much scholarly attention has focused on couples defined as Islamic-Catholic or Muslim-Christian, which represent a paradigmatic case study of \u201cmixedness\u201d that typically incorporates differences pertaining to ethnicity, class and faith. The challenge of this project gives an empirically adequate exploration of a pattern firmly established in quantitative studies, i.e., that interfaith marriages give rise to high divorce rates. This project thus aims to understand, through an in-depth qualitative study, the daily life of such families: what differences are responsible for tension between spouses, how they deal with this in order to avoid damage to their relationship, and how gender interferes with these problems. Mixed marriages will be a key to examine the whole of society facing new family changes, Islam and religious diversity in everyday life. The research project addresses the EU lines of Horizon 2020, studying one of the major challenges for an \u201cinclusive and multicultural\u201d Europe. The fellowship will provide me with wider competence, publications and connections necessary to apply for an ERC Grant in 2019.", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["747592"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE CATHOLIQUE DE LOUVAIN"], "EU_Contribution": ["EUR 172 800"], "Project_Title": ["House Poetics. An 'assemblage' approach to the production and transmission of value in Bronze Age Crete."], "Total_Cost": ["EUR 172 800"], "Country": ["Belgium"], "Project_ACR": ["HousePoetics"], "Technology_Description": "The Project explores the fundamental social question of the creation of value, by investigating House Societies in Bronze Age Crete (3100-1200 BC). Houses are understood as intergenerational, locus-bound social groups, holding an estate of material and symbolic wealth, transmitted along a real or imaginary line, legitimized by kinship or affinity, or both. Because of their distinct focus on the creation and transmission of value, Houses are an ideal framework for answering this research question, but their longevity makes it difficult to explain change. By fusing Houses with the philosophical and sociological premises of Assemblage theory, which argues that social entities are not fixed but constituted by relationships between humans, non-humans and materials that can territorialize and deterritorialize value, the project creates a new social ontology which perceives Houses in a constant state of becoming, continuously affecting and being affected by the changing social world they inhabit. The methodological advantage of this interdisciplinary model, combining philosophical, sociological, archaeological and scientific perspectives, will be demonstrated empirically through the integrated use of GIS spatial analysis and material culture analysis, in a series of case studies (selected on the basis of availability of good contextual information for primary data and a large corpus of published evidence) targeting three strategic scales of House formation and interaction: a single site (Petras), its regional context (East Crete) and their broader geopolitical networks (the Aegean and the East Mediterranean). Using GIS to explore Houses as Assemblages will offer an original integration of spatial, material and social scales, which can revitalize our understanding of past societies and transform the study of social relations in general.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["752179"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF SOUTHAMPTON"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Time-dependent design and assessment of prestressed steel-concrete composite bridges with external FRP tendons"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["TimePresCompBridge"], "Technology_Description": "Large EU projects and surveys reveal that the frequency and cost of bridge repairs in Europe have significantly increased due to traffic loads higher than those considered in the initial design, harsh environmental conditions, use of de-icing salts especially in countries with cold climates, poor quality of construction materials, and limited maintenance. Most importantly, the aforementioned projects and surveys highlight that current repair and strengthening methods are costly and time-consuming and result in large socio-economic losses due to disruption of traffic flow such as travel delays, longer travel distances, insufficient move of goods, and loss of business. Therefore, bridge owners and bridge engineers urgently seek to transfer into real-life projects more efficient and less disruptive methods for bridge repair, strengthening and maintenance. External post-tensioning is recognised as a powerful technique in the rehabilitation of existing bridges as well as in the construction of new bridges. For the advantages of noncorrosive property and high strength, fibre reinforced polymer (FRP) composites are being increasingly used for external tendons instead of conventional steel ones. Existing research on externally prestressed steel-concrete composite bridges has focused on the short-term loading. However, the inevitable loss of long-term performance of prestressed composite bridges is of primary concern in practice, especially when FRP tendons are used. Therefore, it is necessary to investigate deeply the long-term behaviour of these bridges and, on this basis, to propose practical design guidelines. In this fellowship, an experimental and numerical study will be carried out to understand the time-dependent performance of composite girder bridges with FRP tendons. Long-term tests will be performed. Moreover, a novel computer programme capable of performing time-dependent analysis will be developed and used to conduct an extensive numerical investigation.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["751921"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE CATHOLIQUE DE LOUVAIN"], "EU_Contribution": ["EUR 172 800"], "Project_Title": ["MadbaM: automated tools for precision calculations of the Baryon Asymmetry of the Universe in BSM models"], "Total_Cost": ["EUR 172 800"], "Country": ["Belgium"], "Project_ACR": ["MadbaM"], "Technology_Description": "The measured Baryon Asymmetry of the Universe (BAU) is a firm evidence for the existence of new physics beyond the Standard Model of particle physics (BSM). Despite of that, the offer of scientific software for the high-energy physics community currently misses dedicated tools devoted to precise baryogenesis computations in BSM models. The aim of the present proposal is to fill this gap, providing the necessary tools in order to bring the theoretical computation of the BAU into a precision era, and employing them to use the BAU as a powerful observable for the characterisation and test of physics BSM. The main deliverable will be a scientific software, MadbaM, able to precisely compute the BAU in as many BSM scenarios as possible.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["750627"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF YORK"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Uncovering the Transatlantic History of Turkey Husbandry and Breeding using a Multi-Disciplinary Approach"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["TURKEY"], "Technology_Description": "For 2000 years, turkeys (Meleagris gallopavo) have been kept and raised by indigenous cultures in North and Central America. In the late 15C, European travellers 'discovered' turkeys and quickly introduced them to Europe and beyond. Their popularity has only increased over time, and in both continents, turkeys are now the most commonly raised bird after chicken. Investigations into the emergence of turkey breeding are fundamental to understanding the evolving economic and symbolic relationships between humans and this iconic bird, as well as to provide historical challenges: first, the diversity of the specimens introduced in Europe (subspecies involved, geographic origin) is unknown; second, the diversity of morphologically similar birds raised in the same time (chicken, guinea fowl, peacock) hamper the recognition of early turkeys from America. This research project will pair the zooarchaeological and morphometrics expertise of the applicant, Aur\u00e9lie Manin, with the biomolecular specialists in the BioArCh group at the University of York, UK, to document and explore turkey husbandry practices in Western Europe from 15C to 19C and its integration in pre-existing backyards. Using combined morphometric and biomolecular analyses this project will: 1) document the origins and intensity of turkey breeding in Europe; and 2) explore the changing socio-economic role of turkeys as they spread through modern Western Europe. Fundamentally, the results of this research will address both archaeological and food production issues by exploring the history of turkey husbandry and providing important data on the evolution of modern breeds, management practices and the resilience of modern poultry industry.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["748679"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 212 194,80"], "Project_Title": ["Propagating DNA Modifications Across the Cell Cycle"], "Total_Cost": ["EUR 212 194,80"], "Country": ["Denmark"], "Project_ACR": ["DNAmod_PROPAGATION"], "Technology_Description": "Background", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["747332"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF YORK"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Reading the genetic history of parchment manuscripts."], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SCRIBE"], "Technology_Description": "Medieval texts are a window into the monastic world and an integral part of European written history. Most of our current understanding of the processes of codex construction comes from the careful examination of the clues to manufacture on the object itself, the practice of codicology. Increasingly scholars are interested in the material qualities of the book. How and why were the decisions on the selection of materials made? Recent advances in analytical methods are broadening the reach of codicology in unexpected ways and enabling these questions to be addressed. The SCRIBE project is at the forefront of this burgeoning field of molecular codicology, having developed and implemented an exciting new minimally destructive DNA sampling technique, derived from routine parchment conservation practice. SCRIBE will further implement this method to generate two novel high throughput genomic datasets from parchment manuscripts. Firstly the materiality of the manuscripts will be described by assessing the genetic relationship between the animals used to complete the codices. Secondly SCRIBE will be the first study to combine high throughput metagenomic techniques and novel bioinformatic approaches to a large sample size of documents in multiple archives to look at the microbial fingerprints of parchments, to complement their provenance and curation.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["747424"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Generation of new zebrafish models for the study of the pathogenesis of Huntington\u00b4s disease and for the identification of new therapeutic targets."], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["HUNTINFISH"], "Technology_Description": "Huntington\u00b4s disease (HD) is one of the nine neurodegenerative diseases (ND) caused by (CAG)n trinucleotide tract expansions that encode abnormally long polyglutamine (polyQ) tracts. The common features shared by many ND are the misfolding and aggregation of toxic proteins. Thus, HD recapitulates features of other, more complicated ND. As HD is an autosomal dominant disorder, modeling this disease in vitro and in vivo is straightforward. Unfortunately, HD is, to date, incurable and there are no drugs or therapies that are known to slow or prevent the disease. Thus, the strategies proposed in this project, taking advantage of the unique characteristics of the zebrafish as model organism to study human diseases, will allow me to gain a deeper understanding of its pathogenesis, and to generate tools to accelerate the development of new therapies. Moreover, my findings may have relevance to other ND. First, I propose to generate new zebrafish transgenic lines expressing different forms of human huntingtin (htt) (wild-type/mutant, full-length/exon1) fused to the photoconvertible fluorescent protein Dendra in whole body, neurons or glial cells using the UAS-GAL4 system. Next, I will validate the construct integration in the fish genome and characterize the transgenic lines. After that, I will use these new generated models to study the life cycles of the previously mentioned forms of htt in vivo, and I will examine their clearance kinetics in vivo in different tissues in the context of inhibition/stimulation of autophagy or ubiquitin-proteasome pathways. Moreover, I will assess the role played by the inflammasome in the context of the neuroinflammation present in HD. Finally, I will use these new zebrafish lines to test novel therapeutic targets recently identified in the host lab, in order to develop new treatments for HD.", "To": ["2020-04-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-05-01"], "Project_ID": ["746509"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["WEIZMANN INSTITUTE OF SCIENCE"], "EU_Contribution": ["EUR 170 509,20"], "Project_Title": ["Deciphering cell-cell and cell-microbiome interactions of innate lymphoid cells at the single cell level"], "Total_Cost": ["EUR 170 509,20"], "Country": ["Israel"], "Project_ACR": ["ILCSIGNALLING"], "Technology_Description": "Battling acute and chronic enteric disease is a priority in Europe and worldwide, especially now at the age of widespread antibiotic resistance. A network of gut immune and epithelial cells tolerates commensal microbes, while retaining its ability to initiate a potent response upon pathogenic infection. Whether and how commensal gut microbes affect the capacity of immune system to fight enteric infection remains largely unknown.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["747114"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 200 194,80"], "Project_Title": ["BIOlogical SignaTures of AnhydrobioSIS via comparative transcriptomics on different evolutionary lineages within tardigrades"], "Total_Cost": ["EUR 200 194,80"], "Country": ["Denmark"], "Project_ACR": ["BIOSTASIS"], "Technology_Description": "The current proposal revolves around the dehydration induced state, anhydrobiosis - a survival strategy found among a range of life-forms in face of severe desiccation. Anhydrobiosis is defined by a reversible shut-down of metabolism (biostasis) and it seems to involve adaptations at all levels of organismic organization. The current proposal uses tardigrades as a model to gain novel insight into molecular signatures underlying this unique biological phenomenon. Several molecules have been implicated in the anhydrobiotic mechanism; however, so far studies have been returning contradictory results with respect to the differential expression of genes in pre- and post-anhydrobiotic phases. Interestingly, our preliminary, unpublished data from M\u00f8bjerg lab suggest that there could be lineage specific strategies to anhydrobiosis. Consequently, I will use transcriptome sequencing (RNAseq) and ddPCR to reveal key-player genes and characterize functional pathways involved in i) different stages of anhydrobiosis of single tardigrade species and ii) between different evolutionary lineages within the phylum. The mentioned methods constitute the most important training element of my project. The overall goal of the proposal is to determine potential gene expression signatures for anhydrobiosis establishing a transcription profile that is i) characteristic of a particular physiological state and ii) that could possibly reflect the phylogenetic position of a taxon. My previous extensive experience on phylogenetic and molecular dating methods will, in this respect, be utilized to estimate the chronology of the possible diversification of anhydrobiosis within evolutionary lineages. My research will be conducted at the M\u00f8bjerg lab, which represents one of the world\u2019s leading groups in the field of tardigrade biology. The group is situated at the Department of Biology, University Copenhagen, which is a superbly equipped institution with a high international profile.", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["747087"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["STICHTING KATHOLIEKE UNIVERSITEIT"], "EU_Contribution": ["EUR 260 929,80"], "Project_Title": ["Emerging Visual Expectation in the Brain"], "Total_Cost": ["EUR 260 929,80"], "Country": ["Netherlands"], "Project_ACR": ["EXPECTATION"], "Technology_Description": "Falling raindrops will likely move downwards; red brake lights up ahead will predict a car slowing down. While perception of the world around us feels rich in detail, our brains lack the capacity to analyze every \u2018pixel\u2019 at every time-point. Instead, the brain relies on expectations to compress the total amount of sensory information from the environment. A failure to rely on expectations about visual inputs would lead to catastrophic consequences. For example, an air traffic controller without the ability to predict the likely trajectories of two planes coming in for landing would spell certain disaster. Remarkably, despite the obvious role in adaptively guiding behavior, the cognitive and neural mechanisms supporting perceptual expectations remain poorly understood. I will concurrently measure human behavior and neural responses to address two fundamental, yet outstanding questions: How are expectations about visual input acquired, and what is the impact of behavioral relevance? I anticipate mechanisms of expectation to change with learning and behavioral relevance. For example, driving in the rain, expectations about break lights could amplify this immediately relevant information. Expectations about falling rain, on the other hand, could support the equally important task of suppressing this irrelevant information so you may return home safely.", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["743941"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Sunlight driven carbon-dioxide reduction: Hybrid catalytic systems consisting of molecular catalysts and light-harvesting Quantum-dots and semiconductors"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["CO2RED"], "Technology_Description": "Artificial photosynthesis, in which sunlight is directly used to generate fuels from CO2 and water, is an attractive solution to both global energy challenges and environmental issues caused by rising CO2 levels. However, implementation of such a quasi-carbon-free fuel-economy requires efficient catalysts and light-harvester to power this uphill reaction. The proposed project is aimed at developing novel hybrid photocatalysts and photocathodes for light-induced CO2 reduction using molecular catalysts and semiconductor light-harvesters. Molecular catalysts will be immobilized onto the semiconductor-materials to generate robust photocatalysts, and subsequently, these semiconductor-catalyst assemblies will be transferred to transparent electrodes to build photoelectrodes. The innovative aspect of CO2RED is to employ inexpensive, carbon-based semi-conducting ligh-harvesters (carbon-nitride, carbon quantum dots) and 3d-metal based molecular catalysts, and use robust linkages to interface them with transparent photoelectrodes. Finally, this hybrid photocathode will be tested in a tandem CO2/H2O photoelectrochemical cell by coupling it with a photoanode for water oxidation. The project being at the interface of synthetic, materials, photo- and electro-chemistry, will provide an excellent opportunity for the experienced researcher (ER) to develop a wide range of technical skills. In addition, the fellowship will allow the ER to gain important complementary skills including proposal writing, manuscript preparation, public outreach, networking, and IPR protection that will be invaluable for his independent career. The combination of the cutting-edge science and training excellence of the project will greatly improve the ER\u2019s career prospect and enhance the host group\u2019s international reputation.", "To": ["2020-02-29, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["745604"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF YORK"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Quantum Energy Conditions and Singularity Theorems"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["QuEST"], "Technology_Description": "The proposed project explores an important open question in mathematical physics today: the occurrence of singularities in spacetime - places where the usual understanding of physics breaks down. For example, singularities may exist at the center of black holes, or have occurred at the beginning of the universe. Singularity theorems, developed over the past 50 years following pioneering work of Penrose and Hawking, are mathematically rigorous results that imply that singularities are inevitable provided the matter content of the universe obeys a suitable energy conditions. Although forms of matter described by quantum field theory can violate the original energy conditions, recent developments provide hope that singularity theorems can be proved even in this case. To date, however, no known singularity theorem fully corresponds to the behaviour of quantum fields or takes into account the backreaction of the quantum field on the spacetime. The goal of this project is to establish singularity theorems for quantised matter using recent work by the researcher and the supervisor as a base. This will be approached in several ways (a) new quantum energy inequalities will be proved that are suitable for use in singularity theorems; (b) new singularity theorems will be proved using a transversely smeared version of the averaged null energy condition; (c) analogues of singularity theorems will be investigated in the context of semiclassical gravity. The combination of the complementary expertise of the researcher and the supervisor is essential to the success of this project. Moreover the researcher will receive training from the supervisor in mathematically rigorous approaches to quantum field theory and relativity, which will broaden her knowledge and expertise. This project will help to resolve a major problem in mathematical physics today and provide insight into how the universe works.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["744037"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN"], "EU_Contribution": ["EUR 175 866"], "Project_Title": ["Algebraic Covering Codes Enabling Network Transmissions"], "Total_Cost": ["EUR 175 866"], "Country": ["Ireland"], "Project_ACR": ["ACCENT"], "Technology_Description": "Applications of rank-metric codes arise ever more frequently in network communications problems, and yet their mathematical theory is still in its infancy. To date attention has almost exclusively focussed on very special classes of codes and their generalizations. ", "To": ["2020-04-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-05-01"], "Project_ID": ["740880"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF EDINBURGH", "THE UNIVERSITY OF EDINBURGH"], "EU_Contribution": ["EUR 139 986"], "Project_Title": ["Portable Characterisation of Sperm Motility"], "Total_Cost": ["EUR 139 986"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["PorCSperM"], "Technology_Description": "Based on an ongoing ERC project on characterising and studying the motility of highly-idealised, model micro-swimmers, we have built and validated a first-generation portable prototype device for assaying accurately bull sperm motility. To move to a more advanced prototype requires integrated software and hardware development and the setting up of standard protocols to render the measurement procedure robust for non-expert operators. Such a device, with integrated hardware and software, for Portable Characterisation of Sperm Motility (PorCSperM) will assembled and applied to bull semen in this project, but is in principle applicable to other animals, and perhaps also to human fertility.", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["727774"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE", "INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE"], "EU_Contribution": ["EUR 1 998 750"], "Project_Title": ["Robust algorithms for learning from modern data"], "Total_Cost": ["EUR 1 998 750"], "Country": ["France", "France"], "Project_ACR": ["SEQUOIA"], "Technology_Description": "Machine learning is needed and used everywhere, from science to industry, with a growing impact on many disciplines. While first successes were due at least in part to simple supervised learning algorithms used primarily as black boxes on medium-scale problems, modern data pose new challenges. Scalability is an important issue of course: with large amounts of data, many current problems far exceed the capabilities of existing algorithms despite sophisticated computing architectures. But beyond this, the core classical model of supervised machine learning, with the usual assumptions of independent and identically distributed data, or well-defined features, outputs and loss functions, has reached its theoretical and practical limits.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["724063"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 1 868 855"], "Project_Title": ["Perceptual encoding of high fidelity light fields"], "Total_Cost": ["EUR 1 868 855"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["EyeCode"], "Technology_Description": "One of the grand challenges of computer graphics has been to generate images indistinguishable from photographs for a na\u00efve observer. As this challenge is mostly completed and computer generated imagery starts to replace photographs (product catalogues, special effects in cinema), the next grand challenge is to produce imagery that is indistinguishable from the real-world.", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["725253"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET", "KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 1 758 742"], "Project_Title": ["Chemical Tools for Unravelling Sirtuin Function"], "Total_Cost": ["EUR 1 758 742"], "Country": ["Denmark", "Denmark"], "Project_ACR": ["SIRFUNCT"], "Technology_Description": "It was recently realized that lysine acetylation affects a wide variety of cellular processes in addition to the initially recognized histone related gene regulation. Together with recent groundbreaking results, revealing the presence of additional acyllysine modifications, the basis for a paradigm shift in this area was formed. Examples of enzymes formerly thought to be lysine deacetylases, have been shown to cleave these new types of lysine modification and members of the sirtuin class of enzymes play a central role.", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["725172"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN", "LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN"], "EU_Contribution": ["EUR 1 928 400"], "Project_Title": ["Relocating Modernism: Global Metropolises, Modern Art and Exile"], "Total_Cost": ["EUR 1 928 400"], "Country": ["Germany", "Germany"], "Project_ACR": ["METROMOD"], "Technology_Description": "Breaking new ground, METROMOD proposes a rewriting of modern art history as a history of global interconnections, spurred by migration movements and rooted in cities. Revising the historiography of modern art, which still continues to be dominated by the hegemonic and normative narratives of (Western) European Modernism and ignores the significance of exile movements, METROMOD conceptualizes art history as a result of interrelations and negotiations in global contact zones, unstable flows, transformations and crises. In its analysis, METROMOD focuses on the first half of the 20th century. During this era the modern movement emerged as a paradigm in art and architecture, and rapid urbanization took place globally; thousands of persecuted European modern artists fled their homes, re-establishing their practices in metropolises across the world. Reflecting both the geographical extent of these exile movements and their local urban impact METROMOD examines 6 key migrant destinations\u2014the global cities of London, New York, Buenos Aires, Istanbul, Shanghai and Bombay (now Mumbai)\u2014following three main objectives: to explore transformations in urban topographies, identifying artistic contact zones and places of transcultural art production; to investigate networks of exiled and local artists as well as collaborative projects and exhibitions; and to analyse art publications and discourse generated in centres of exile. Digital mapping will locate sites of artistic migration in the cities and demonstrate linkages between transforming metropolises and flows of people and objects around the world. The conceptual triangle of modernism, migration and the metropolis forms the foundation of an innovative comparative, interdisciplinary methodology. As well as impacting art history, METROMOD will provide a historical perspective from which today\u2019s mass migration movements can be better understood.", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["724649"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITY OF SOUTHAMPTON"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Muslim Antisemitism in Colonial Morocco"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["MORA"], "Technology_Description": "European colonialism in Muslim societies represented a turning point for the powerful European influence that was widespread throughout the Middle East. With European Jews acquisition of land in Palestine, Arab nationalism started to incorporate antisemitic ideology into their texts and discourses. The creation of the Jewish state in 1948 accelerated this process. Thus, paradoxically, while the presence of antisemitism among European societies has been marginal since the end of World War II, socially and politically discredited, and even prosecuted, antisemitic voices have gained ground in the Middle East. With the immigration of the North African populations (both Jewish and Muslim) from the second half of the twentieth century, some conflicts have arisen in Europe as well, particularly, but not exclusively, in France. Therefore, the colonial period is crucial to understanding not only when, how and why European antisemitism entered northern Africa, and later returned to Europe, but above all how it interacted with the local notions and prejudices about Jews in Muslim societies. Further research is required to analyse in detail what the integration of a foreign ideology means and involves for native popular ideas and local prejudices. In this research project, the researcher will address these issues through historical anthropology and ethnography in the context of inter-religious relations in Spanish Colonial Morocco.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["745752"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KAROLINSKA INSTITUTET", "KAROLINSKA INSTITUTET"], "EU_Contribution": ["EUR 2 480 889"], "Project_Title": ["Restoration of tumor suppressor function by induction of translational read-through of premature termination codons - a strategy for improved cancer therapy"], "Total_Cost": ["EUR 2 480 889"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["TRANSREAD"], "Technology_Description": "Tumor suppressor genes such as TP53, RB1, PTEN and APC are frequently inactivated in sporadic and inherited human tumors. A significant fraction of the mutations in these genes are nonsense mutations that lead to premature termination of translation and expression of truncated unstable and non-functional proteins. We will identify and characterize novel molecules that can induce translational read-through of premature termination codons in nonsense mutant TP53 and expression of full length p53 protein. Hits will be tested for their effect on nonsense mutant RB1, PTEN and APC. We will also elucidate the molecular mechanism of action of the identified compounds by CETSA and other techniques. Moreover, we will test hit compounds on primary tumor cells from patients ex vivo, and generate mouse knock-in tumor models with nonsense mutant tumor suppressor genes for further characterization of hits. We will take the most promising hits through preclinical development towards clinical trials. Our aim is to develop novel and efficient targeted therapy for tumors with nonsense mutations in the TP53, RB1, PTEN and/or APC tumor suppressor genes.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["694825"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["KAROLINSKA INSTITUTET", "KAROLINSKA INSTITUTET"], "EU_Contribution": ["EUR 2 279 406"], "Project_Title": ["Targeting oxidative repair proteins for treatment of cancer and inflammation"], "Total_Cost": ["EUR 2 279 406"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["TAROX"], "Technology_Description": "Oxidative damage and defects in DNA repair are frequently underlying many diseases, e.g., cancer, autoimmune diseases, ischemia/reperfusion injury, neurodegenerative disorders, viral diseases and ageing. Although some molecular understanding into oxidative DNA lesions and repair proteins exist, a thorough understanding on the link to diseases is largely missing, and therapies exploiting oxidative DNA damage and repair have not emerged. Here, we will study mechanisms of nucleotide metabolism and oxidative DNA damage and repair, and generate tools and make use of \u2018omics\u2019 approaches to explore the function of the Nudix and glycosylases family enzymes in relation to oxidative metabolism. Furthermore, we will progress and understand the basic mechanisms how oxidative DNA lesions are processed and kill cells. Importantly, we will develop small molecule inhibitors targeting Nudix and glycosylases, e.g. MTH1, NUDT15 and OGG1, and use our newly developed inhibitors to increase our knowledge of these enzymes in oxidative metabolism and disease. We will further optimize these inhibitors into drugs and explore therapeutic approaches in cancer and inflammation as well as in exploratory studies in a variety of diseases involving oxidative stress. Altogether, in this programme we contribute to deepen our knowledge into the fundamental biology of oxidative stress and its links with disease, and providing the scientific community with an innovative repertoire of selective inhibitors for numerous enzymes involved in repair of oxidative lesions. This will enable exploratory basic science discoveries as well as potential novel therapeutic interventions \u2018outside the box\u2019. The programme will also generate high value to the industrial competitiveness of Europe in form of novel inhibitors for treatment of diseases.", "To": ["2021-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-08-01"], "Project_ID": ["695376"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["KAROLINSKA INSTITUTET", "KAROLINSKA INSTITUTET"], "EU_Contribution": ["EUR 2 500 000"], "Project_Title": ["Functional connectome of brainstem circuits that control locomotion"], "Total_Cost": ["EUR 2 500 000"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["LocomotorIntegration"], "Technology_Description": "Locomotion is a complex motor act that is used in many daily life activities and is the output measures of a plethora of brain behaviors. The planning and initiation of locomotion take place in the brain and brainstem, while the execution is accomplished by activity in neuronal networks in the spinal cord itself. Recent experiments have provided significant insight to the organization of the executive spinal locomotor networks. However, little is known about the brainstem control of these networks. Here, I propose to provide a unified understanding of the functional connectome of the key brainstem networks that control locomotion in mammals needed to select appropriate locomotor outputs. To obtain these goals we will develop a suite of transgenic mouse models with optogenetic or chemogenetic switches in defined populations of brainstem neurons combined with the possibility to use state-of-the-art cell-specific electrophysiological and anatomical connectivity studies. We will reveal the functional organization of \u2018go\u2019 and \u2018stop\u2019 command systems in the brainstem that are directly upstream from the spinal locomotor networks and the mechanisms for how spinal networks are selected. We will further functionally deconstruct the next network layer in midbrain structures that control the \u2018go\u2019 and \u2018stop\u2019 command systems. Our research takes a specific approach to provide mechanistic insight to the integrated movement function by building the motor matrix in a functional chain from the locomotor\u2013related spinal cord neurons that have been identified to midbrain neurons. A segment of our research will link these networks to locomotor impairments after basal ganglia dysfunction. The work has the potential to make a breakthrough in our understanding of how complex movements are generated by the brain and has translational implications for patients with movement disorders. It will push boundaries in the universal effort that aims to comprehend how brain networks create behaviors.", "To": ["2021-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-08-01"], "Project_ID": ["693038"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 212 194,80"], "Project_Title": ["Intestine-on-a-chip for investigating microbioal-epithelail interaction"], "Total_Cost": ["EUR 212 194,80"], "Country": ["Denmark"], "Project_ACR": ["iChip"], "Technology_Description": "The small intestine forms a barrier that protects us against the outer world. Here commensal bacteria are tolerated while pathogens are effectively fought off. Occasionally, however, pathogenic bacteria colonize the intestine causing different diseases, which constitute a huge burden worldwide. The ability to study interactions of pathogenic bacteria with the intestine will provide new insights into the disease mechanisms, and new therapeutic targets and ways to prevent disease occurrence. Current animal and 2D models based on tumor cell lines both have shortcomings as they react differently to pathogenic bacteria when compared to healthy human tissues.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["746270"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KAROLINSKA INSTITUTET", "KAROLINSKA INSTITUTET"], "EU_Contribution": ["EUR 1 422 338,77"], "Project_Title": ["Shaping of the Human Immune System by Primal Environmental Exposures In the Newborn Child"], "Total_Cost": ["EUR 1 422 338,77"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["Born-Immune"], "Technology_Description": "Immune systems are highly variable, but the sources of this variation are poorly understood. Genetic variation only explains a minor fraction of this, and we are unable to accurately predict the risk of immune mediated disease or severe infection in any given individual. I recently found that immune cells and proteins in healthy twins vary because of non-heritable influences (infections, vaccines, microbiota etc.), with only minor influences from heritable factors (Brodin, et al, Cell 2015). When and how such environmental influences shape our immune system is now important to understand. Birth represents the most transformational change in environment during the life of any individual. I propose, that environmental influences at birth, and during the first months of life could be particularly influential by imprinting on the regulatory mechanisms forming in the developing immune system. Adaptive changes in immune cell frequencies and functional states induced by early-life exposures could determine both the immune competence of the newborn, but potentially also its long-term trajectory towards immunological health or disease. Here, I propose a study of 1000 newborn children, followed longitudinally during their first 1000 days of life. By monitoring immune profiles and recording many environmental influences, we hope to understand how early life exposures can influence human immune system development. We have established a new assay based on Mass Cytometry and necessary data analysis tools (Brodin, et al, PNAS 2014), to simultaneously monitor the frequencies, phenotypes and functional states of more than 200 blood immune cell populations from only 100 microliters of blood. By monitoring environmental influences at regular follow-up visits, by questionnaires, serum measurements of infection, and gut microbiome sequencing, we aim to provide the most comprehensive analysis to date of immune system development in newborn children.", "To": ["2021-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-07-01"], "Project_ID": ["677559"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["KAROLINSKA INSTITUTET", "KAROLINSKA INSTITUTET"], "EU_Contribution": ["EUR 1 941 531"], "Project_Title": ["Understanding microbe-induced stomach cancer \u2013 the key to a workable strategy for worldwide prevention"], "Total_Cost": ["EUR 1 941 531"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["PreventStoCan"], "Technology_Description": "Stomach cancer is the 4th most common cancer and 2nd leading cause of cancer-related death worldwide. The aim of this proposal is to deepen the understanding of mechanisms involved in microbe-induced gastric carcinogenesis, which will facilitate risk stratification for identification of high-risk groups and may offer new opportunities for pharmacological and probiotic prevention. We hypothesize that novel H. pylori genotypic variation can predict carcinogenicity. The cancer-causing H. pylori strains may no longer be present at the time of cancer diagnosis, displaced by a changed microenvironment and invading microorganisms. We further hypothesize that the composition of invading microorganisms determines the risk of stomach cancer. To test these hypotheses, we will perform a case-control study nested within a historic cohort of patients with gastric biopsies taken decades ago. For cases who developed stomach cancer several years after index biopsy and their matched controls, paraffin-embedded blocks will be retrieved for metagenomic analysis of H. pylori and other microfloras, using our new method with laser capture micro-dissection, DNA amplification and sequencing. Interactions of host response and environmental exposures with the gastric microbiome will also be checked. To explore the molecular mechanism underlying the gastric carcinogenesis, we will further examine gastric epigenetic changes and mutation profiles by novel methods which require minute amount of starting material. Moreover, we will develop non-invasive tests for infections with carcinogenic strains of H. pylori and other microorganisms, which can easily be deployed in low-resource countries. This project will not only contribute significantly to reducing the worldwide burden of this dreaded malignancy, but also broaden our understanding of the mechanisms linking infection, inflammation and cancer development, and open a door for research using the vast resources of archived pathology materials.", "To": ["2021-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-07-01"], "Project_ID": ["682663"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["KAROLINSKA INSTITUTET", "KAROLINSKA INSTITUTET"], "EU_Contribution": ["EUR 1 493 125"], "Project_Title": ["Therapeutic and Biomarker Potential of long non-coding RNAs in Vascular Disease"], "Total_Cost": ["EUR 1 493 125"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["NORVAS"], "Technology_Description": "The contribution of cardiovascular disease to human morbidity and mortality continues to steadily increase in our aging European society. In response, extraordinary efforts have been launched to determine the molecular and pathophysiological characteristics of its etiology. The collective work of multiple research groups has uncovered a complex transcriptional and post-transcriptional regulatory milieu, which is believed to be essential for maintaining cardiovascular homeostasis. Recently, non-coding RNAs, especially the ones with antisense capabilities such as microRNAs or \u2018natural antisense transcripts\u2019 (NATs) have received much attention. They have been identified as important transcriptional and post-transcriptional inhibitors of gene expression. ", "To": ["2021-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["679777"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["KAROLINSKA INSTITUTET", "KAROLINSKA INSTITUTET", "OXCIA AB"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["COmmercializing first-in-class dCTPase Inhibitors for treatment of hematological Cancers"], "Total_Cost": ["EUR 150 000"], "Country": ["Sweden", "Sweden", "Sweden"], "Project_ACR": ["CODIC"], "Technology_Description": "In our ERC grant GEnetic NEtworks as a tool for anti-CAncer Drug Development we used siRNA screening and genetic networks to identify dCTPase being involved in DNA repair and replication. Further studies revealed that dCTPase plays a role in the degradation of nucleoside analogues used in cancer treatment. We then used an RNAi approach to validate dCTPase as a target to improve nucleoside analogue therapy. The dCTPase protein was purified and we set up an enzymatic high-throughput assay to screen >65,000 compounds, which generated hits that inhibit dCTPase (IC50~1-10\u03bcM). Using in house medicinal chemistry we developed TH1217, a low nM potent and selective dCTPase inhibitor with favourable pharmacokinetic properties. TH1217 synergistically induces apoptosis and cell death in combination with cytidine analogue treatment in cancer cells in vitro and in vivo, but shows no increased toxicity in nontransformed dividing cells. Here, we want to explore the commercial potential of the dCTPase inhibitors identified in the ERC grant.", "To": ["2017-06-30, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2015 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-01-01"], "Project_ID": ["692908"], "Call_for_Proposal": ["ERC-2015-PoC"]}, -{"Partners": ["KAROLINSKA INSTITUTET", "KAROLINSKA INSTITUTET"], "EU_Contribution": ["EUR 1 895 155"], "Project_Title": ["Reversing the epigenetic state of oligodendrocyte precursors cells in multiple sclerosis"], "Total_Cost": ["EUR 1 895 155"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["EPIScOPE"], "Technology_Description": "Oligodendrocytes (OL) are glial cells that mediate myelination of neurons, a process that is defective in multiple sclerosis (MS). Although OL precursor cells (OPCs) can initially promote remyelination in MS, this regenerative mechanism eventually fails in progressive MS. OPCs go through several epigenetic states that ultimately define their potential to differentiate and myelinate. OPCs in progressive MS stall in a distinct epigenetic state, incompatible with differentiation and remyelination. We hypothesize that these OPCs regress to an epigenetic state reminiscent of the state of embryonic OPCs, which remain undifferentiated.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["681893"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["KAROLINSKA INSTITUTET", "KAROLINSKA INSTITUTET"], "EU_Contribution": ["EUR 1 950 033"], "Project_Title": ["Prosaposin and GPR37 in synucleinopathies"], "Total_Cost": ["EUR 1 950 033"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["PROGSY"], "Technology_Description": "The next breakthrough in the treatment of synucleinopathies, incl Parkinson\u00b4s disease (PD), will be aimed at interference of disease progression based on insights into the underlying pathogenic process. The pathological hallmark of PD are Lewy bodies (LBs), in which \u03b1-synuclein is the major constituent together with other PD-linked gene products (DJ-1, LRRK2, parkin, and GBA) and aggregated GPR37. GPR37 is exceptional among GPCRs having a high propensity for intracellular receptor accumulation and aggregation leading to neurotoxicity. However, unexpectedly, our results suggest that GPR37 is neuroprotective in dopaminergic when located at the plasma membrane. Consistently, prosaposin (PSAP), and its neurotrophic fragment prosaptide, were recently identified as agonists at GPR37. PSAP is a neuroprotective protein that regulates intracellular lysosomal enzyme function, with saposin C being a co-factor of GBA. In addition, we hypothesize that PSAP is secreted following cellular stress and, via membraneous GPR37, cue dopamine neurons to initiate survival pathways. Pivotal to this programme is modeling and analysis of the atomic structures of GPR37 in complex with prosaptide, which will grossly facilitate mechanistic understanding and drug development with potential use in diagnosis and treatment. Novel applications and technological advancements of fluorescence correlation spectroscopy will be implemented for single molecule trafficking of GPR37 and its ligands and will examine whether GPCR multimerization beyond dimer formation may be neurotoxic. Normal and cGPR37KO mice will be virally transduced by \u03b1-synuclein to delineate in the relative contributions of improved lysosomal function versus GPR37 agonism for neuroprotection by prosaptides. Evolving from the autopsy studies that anti\u2013GPR37 label LBs and that prosaposin is released upon cellular injury, we will develop GPR37 ligands as PET tracers for LBs in synucleinopathies.", "To": ["2020-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-08-01"], "Project_ID": ["649116"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["KAROLINSKA INSTITUTET", "KAROLINSKA INSTITUTET"], "EU_Contribution": ["EUR 1 923 060"], "Project_Title": ["Revealing Allele-level Regulation and Dynamics using Single-cell Gene Expression Analyses"], "Total_Cost": ["EUR 1 923 060"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["Allelic Regulation"], "Technology_Description": "As diploid organisms inherit one gene copy from each parent, a gene can be expressed from both alleles (biallelic) or from only one allele (monoallelic). Although transcription from both alleles is detected for most genes in cell population experiments, little is known about allele-specific expression in single cells and its phenotypic consequences. To answer fundamental questions about allelic transcription heterogeneity in single cells, this research program will focus on single-cell transcriptome analyses with allelic-origin resolution. To this end, we will investigate both clonally stable and dynamic random monoallelic expression across a large number of cell types, including cells from embryonic and adult stages. This research program will be accomplished with the novel single-cell RNA-seq method developed within my lab to obtain quantitative, genome-wide gene expression measurement. To distinguish between mitotically stable and dynamic patterns of allelic expression, we will analyze large numbers a clonally related cells per cell type, from both primary cultures (in vitro) and using transgenic models to obtain clonally related cells in vivo.", "To": ["2020-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-07-01"], "Project_ID": ["648842"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["UNIVERSITY OF LEEDS"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Vulnerable trait-combinations in corals and fishes and their management"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["TRIM"], "Technology_Description": "Vulnerable trait-combinations in corals and fishes and their management (Traits coRals fIshes Management)", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["747102"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KAROLINSKA INSTITUTET", "KAROLINSKA INSTITUTET"], "EU_Contribution": ["EUR 149 693"], "Project_Title": ["Validation of a conceptually new treatment for glioblastoma multiforme with an IP protected small molecule"], "Total_Cost": ["EUR 149 693"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["GlioVac"], "Technology_Description": "Glioblastoma multiforme (GBM) is the most aggressive form of brain cancer with marginal life expectancy even with the most aggressive available therapy. We have identified a previously unanticipated vulnerability of GSCs which when targeted, leads to a rapid and complete cell death of all tumor cells isolated from nine different patients diagnosed with GBM. The cellular mechanism has been identified and involves an increased vulnerability of GSCs to massive vacuolization which can be induced by a small molecule, termed Vacquinol-1. The vacuolization results from an induction of massive macropinocytosis leading to cytoplasmic membrane rupture and cell death. Vacquinol-1 reduces viability in vitro with approximately 70 times greater potency than current chemotherapy and efficiently and significantly reverses disease and prolongs survival in animal models of human GBM. Vacquinol-1 is highly selective for glioblastoma cells and is not present in other examined cell types, including astrocytes from the brain. Vacquinol-1 has favorable pharmacokinetics, oral bioavailability and exhibits excellent overall preclinical characteristics. Synthetic chemical expansion of Vacquinol-1 reveals an exquisitely delicate structure activity relationship. IP protection has been filed. In order to be able to validate this discovery into an innovation and possible commercialization we need to: 1) Compare potency and efficacy with competing compounds in development stage. 2) Establish optimized dosage regimen from in vitro and in vivo cytotoxicity and brain exposure measurements. 3) Develop a GMP-compatible stereo-selective synthesis of an appropriate Vacquinol-1 isomer for amending composition of matter to patent and pre-GLP/GLP toxicological and phase I clinical trials. 4) Together with Karolinska Institutet Innovations AB protect the intellectual property, validate commercialization potential and establish a development plan.", "To": ["2016-08-31, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2014 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-03-01"], "Project_ID": ["637047"], "Call_for_Proposal": ["ERC-2014-PoC"]}, -{"Partners": ["UNIVERSITE GRENOBLE ALPES"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Amorphous Precursors in Biomineralization."], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["AMORPREBIO"], "Technology_Description": "Calcium carbonate (CaCO3) is a widely studied inorganic compound very abundant in nature as a mineral and a biomineral. It is an important building block of biological bodies, making up the structure of invertebrate organisms. CaCO3 is also a key compound for CO2 sequestration strategies. Recent investigations have reported a so-called non-classical pathway for CaCO3 formation, which involves the formation of an amorphous precursor: amorphous calcium carbonate (ACC), which acts as an intermediate in the formation of the final CaCO3 crystalline polymorphs (calcite and aragonite). This has been reported for biominerals such as the sea urchin spicules, which are made of calcite and the shells of Haliotis tuberculata made of aragonite. However, despite these advances on the characterization of the amorphous precursor, little is known about the polymorph selection mechanism. Amorphous carbonates have also been discovered in several strains of cyanobacteria some of these cyanobacteria mineralize CaCO3 internally even in solutions that are under-saturated with respect to all CaCO3 polymorphs. These cyanobacteria have the ability of concentrating elements from the culture medium in the amorphous carbonates. They have also shown chemical selectivity, and interesting core-shell chemical distributions of some ions such as Ba2+, Ca2+ and Sr2+. These carbonates may serve as a storage reservoir of Ca and inorganic C for the cells if they can be stable on one hand under certain conditions but easily remobilizable as well on the other hand. However, the structural characteristics of these carbonate formations inclusions and their impact on the crystallization pathway are poorly known. Therefore, the goal of this project is to shed light into the role of the AAC in the (bio)mineralization process. This aim will be tackled under two approaches abiotic and biogenic induced conditions, which correspond to the two different parts proposed for the development of this project.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["747597"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["STOCKHOLMS UNIVERSITET", "STOCKHOLMS UNIVERSITET"], "EU_Contribution": ["EUR 1 967 755"], "Project_Title": ["Understanding the speed limits of magnetism"], "Total_Cost": ["EUR 1 967 755"], "Country": ["Sweden", "Sweden"], "Project_ACR": ["MAGNETIC-SPEED-LIMIT"], "Technology_Description": "While the origin of magnetic order in condensed matter is in the exchange and spin-orbit interactions, with time scales in the subpicosecond ranges, it has been long believed that magnetism could only be manipulated at nanosecond rates, exploiting dipolar interactions with external magnetic fields. However, in the past decade researchers have been able to observe ultrafast magnetic dynamics at its intrinsic time scales without the need for magnetic fields, thus revolutionising the view on the speed limits of magnetism. Despite many achievements in ultrafast magnetism, the understanding of the fundamental physics that allows for the ultrafast dissipation of angular momentum is still only partial, hampered by the lack of experimental techniques suited to fully explore these phenomena. However, the recent appearance of two new types of coherent radiation, single-cycle THz pulses and x-rays generated at free electron lasers (FELs), has provided researchers access to a whole new set of capabilities to tackle this challenge. This proposal suggests using these techniques to achieve an encompassing view of ultrafast magnetic dynamics in metallic ferromagnets, via the following three research objectives: (a) to reveal ultrafast dynamics driven by strong THz radiation in several magnetic systems using table-top femtosecond lasers; (b) to unravel the contribution of lattice dynamics to ultrafast demagnetization in different magnetic materials using the x-rays produced at FELs and (c) to directly image ultrafast spin currents by creating femtosecond movies with nanometre resolution. The proposed experiments are challenging and explore unchartered territories, but if successful, they will advance the understanding of the speed limits of magnetism, at the time scales of the exchange and spin-orbit interactions. They will also open up for future investigations of ultrafast magnetic phenomena in materials with large electronic correlations or spin-orbit coupling.", "To": ["2022-01-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-02-01"], "Project_ID": ["715452"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["UNIVERSIDAD DE OVIEDO", "UNIVERSIDAD DE OVIEDO"], "EU_Contribution": ["EUR 1 459 219"], "Project_Title": ["Nano-optics on flatland: from quantum nanotechnology to nano-bio-photonics"], "Total_Cost": ["EUR 1 459 219"], "Country": ["Spain", "Spain"], "Project_ACR": ["2DNANOPTICA"], "Technology_Description": "Ubiquitous in nature, light-matter interactions are of fundamental importance in science and all optical technologies. Understanding and controlling them has been a long-pursued objective in modern physics. However, so far, related experiments have relied on traditional optical schemes where, owing to the classical diffraction limit, control of optical fields to length scales below the wavelength of light is prevented. Importantly, this limitation impedes to exploit the extraordinary fundamental and scaling potentials of nanoscience and nanotechnology. A solution to concentrate optical fields into sub-diffracting volumes is the excitation of surface polaritons \u2013coupled excitations of photons and mobile/bound charges in metals/polar materials (plasmons/phonons)-. However, their initial promises have been hindered by either strong optical losses or lack of electrical control in metals, and difficulties to fabricate high optical quality nanostructures in polar materials. ", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["715496"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["UNIVERSIDAD POMPEU FABRA", "UNIVERSIDAD POMPEU FABRA"], "EU_Contribution": ["EUR 149 750"], "Project_Title": ["Emulating visual perception of contrast for image capture, post-production and synthesis"], "Total_Cost": ["EUR 149 750"], "Country": ["Spain", "Spain"], "Project_ACR": ["VIPERCON"], "Technology_Description": "A significant research outcome from the IP4EC ERC Starting Grant has been to propose a vision model for contrast perception that can be realized as an image-dependent non-linear transformation that can accurately reproduce the detail and contrast directly visible in a scene. The model is based on findings from psychophysical and neurophysiological studies and is well suited to the statistics of natural images. The resulting transform is automatic (no need for user-selected parameters) and of extremely low computational complexity, making it a good candidate for real-time applications. It produces images and videos that look natural, without any halos, spurious colors or artifacts. The model has been validated through psychophysical tests that confirm that it outperforms other state of the art algorithms in terms of users\u2019 preference. A European patent application has been filed.", "To": ["2018-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["727255"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["JOHN INNES CENTRE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Unravelling the molecular Basis of epigenetic silencing: what factors define a gene as a Polycomb target?"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["AMBITION"], "Technology_Description": "The current lack of mechanistic understanding regarding how Polycomb targets are selected severely limits the potential for epigenetic manipulation in many eukaryotic systems. This proposal therefore addresses a key central question in chromatin biology: which factors specify a gene for Polycomb mediated silencing? ", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations"], "From": ["2017-04-01"], "Project_ID": ["753000"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["DB SYSTEMTECHNIK GMBH"], "EU_Contribution": ["EUR 100 018,80"], "Project_Title": ["Acoustic monitoring of railway track quality"], "Total_Cost": ["EUR 100 018,80"], "Country": ["Germany"], "Project_ACR": ["AMONTRACK"], "Technology_Description": "The need for reduced costs and higher system reliability will make condition-based maintenance a key technology in the railway sector in the nearer future. However, reliable and adequate methods for monitoring track conditions, preferably by adding monitoring devices to ordinary rolling stock, are still far from being in place. The proposed project focuses on acoustic track monitoring and aims at pushing forward this monitoring technique to a point, where track faults such as squats, deteriorated rail joints or hanging sleepers can be automatically detected and quantified. This is achieved by combining advanced measurement techniques - involving sound pressure signals due to radiation from rail and wheel as well as axle box vibrations \u2013 with advanced simulation techniques for wheel/rail interaction. DB Systemtechnik GmbH as my host supplying all needed measurement techniques and myself as expert in the modelling of wheel/rail interaction will meet and utilize synergy effects from merging our competences in order to design and implement a methodology for acoustic track monitoring that is clearly beyond today's state-of-the-art. Furthermore, being an active member of the group at DB Systemtechnik will give me access to experience, knowhow and education in the railway technology sector. This is a unique possibility for me to broaden my career profile. It will make me an attractive employee both in the railway technology sector as well as in academia. Crossing the boarders of academia and preparing myself for leadership during my fellowship will be a strong support for my goal to become a research leader in academia. It will widen my professional network and offer a possibility for strong cooperation beyond the lifetime of the project.", "To": ["2019-06-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-SE - Society and Enterprise panel"], "Coordinated_in": ["Germany"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-05-01"], "Project_ID": ["744605"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Eco-lightweight granules for energy efficient applications"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["Eco-LWG"], "Technology_Description": "Buildings in Europe are responsible for more than 40% of total energy consumption and 25% of carbon emissions, mainly due to the high number of old housing stock with very poor insulation systems. This research will develop new energy efficient materials by engineering eco-lightweight granules (eco-LWG) to mitigate these problems. The eco-LWG will have high strength and high water absorption, ~100 wt.%, and be made from widely available waste materials: recycled mixed coloured glass, clay and limestone. The eco-LWG will be used to contain phase change materials (PCM), which use chemical bonds to store and release heat, allowing control of temperature fluctuations. The high level of porosity in the eco-LWG will allow them to absorb and retain much higher levels of PCM than has previously been possible using existing lightweight aggregates. Both the eco-LWG and the PCM loaded eco-LWG will be optimised by statistical design methodology and they will be used to develop new energy efficient construction products. Two impregnation methods will be compared to introduce the PCM into the eco-LWG: vacuum sorption to achieve maximum PCM uptake and short term immersion to partially fill the connected porosity. These will produce innovative lightweight and high heat-storage materials. Incorporating PCM loaded granules in mortars and other construction materials will result in reduced energy requirements to heat and cool buildings and improve indoor living conditions. ", "To": ["2017-07-31, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-08-01"], "Project_ID": ["658884"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE FRANCIS CRICK INSTITUTE LIMITED"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["RAS/C-RAF interaction: A new pharmacological target in Kras-driven lung cancer."], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["IVORIaN"], "Technology_Description": "Lung adenocarcinoma is the most frequent subtype of lung cancer and patients harbour activating mutations in the KRAS gene in approximately 25% of the cases. Unfortunately, regardless of the outcome of recent studies identifying specific KRASG12C inhibitors, so far, oncogenic KRAS is not a druggable target yet. The best-characterized KRAS effector pathway, the ERK cascade consists of RAF, MEK and ERK proteins that can be inhibited with small molecules targeting their kinase activities. As the development of RAF and MEK kinases inhibitors progressed, feedback loop reactivating the ERK cascade have emerged, inducing resistance to treatment. Thus, new innovative strategies are needed to achieve a more long-term inhibition of this signalling pathway, while reducing detrimental side effects due to MAPK inhibition in normal cells. It has been described more than 20 years ago that RAF directly interacts with RAS through its Ras Binding Domain (RBD), and many research groups have been trying to disrupt this interaction developing allosteric inhibitors as a cancer therapy. At the moment, those molecules need to be improved in order to achieve a strong inhibition of this pathway. Surprisingly, no mouse model actually demonstrates the requirement of RAS/RAF interaction during KRAS-induced lung tumourigenesis. Here, we propose to investigate this crucial question using a new mouse model allowing us to conditionally disrupt RAS/RAF interaction in vivo. Using the leading mouse model to study lung cancer (LSL-KrasG12D/+; p53-/- mice), we will take advantage of both Cre/LoxP and FLIPo/Frt technologies to investigate the role of RAS/RAF interaction during lung tumours maintenance, as well as its function in tumour/host crosstalk and normal physiology. All together, these investigations will provide important insights into the clinical relevance of developing RAS interaction inhibitors for the treatment of RAS-driven tumours.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations"], "From": ["2017-06-01"], "Project_ID": ["748273"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CENTRALESUPELEC", "CENTRALESUPELEC"], "EU_Contribution": ["EUR 149 682,86"], "Project_Title": ["CacheMire: Wireless Edge Caching Platform"], "Total_Cost": ["EUR 149 682,86"], "Country": ["France", "France"], "Project_ACR": ["CacheMire"], "Technology_Description": "Mobile data traffic sharply increases each year, due to the rich multi-media applications, video streaming, social networks, and billions of connected users and devices. This increasing mobile data traffic is expected to reach by 2018 roughly 60% of total network traffic. In this regard, caching contents at the edge of the network, namely at the base station and user terminals, is a promising way of offloading the backhaul (especially crucial in dense network deployments) and decreasing the end-to-end content access delays, since the requested contents become very close to the users. Therefore, caching has the potential to become the third key technique for wireless systems sustainability. The goal of this proof of concept is to realize a prototype of such an architecture which enables caching at the edge of the network, and called as \u201cCacheMire\u201d. In particular, we shall focus on development of the first version of CacheMire, which aims to 1) provide an application programming interface (API) to website developers (or content providers); 2) build a set of software/hardware tools to track/collect users' content access statistics under privacy constraints and regulations; 3) and design a storage unit/box for caching strategic contents (i.e., images, videos, files, news) at the base stations and access points. In addition, we aim to combine advanced physical layer techniques with caching so that resources in the uplink/downlink of next generation 5G wireless networks can be further optimized.", "To": ["2018-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["727682"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["OBSERVATOIRE DE PARIS", "UNIVERSITY OF DURHAM", "MICROGATE SRL", "PLDA SAS"], "EU_Contribution": ["EUR 3 760 793,75"], "Project_Title": ["Green Flash, energy efficient high performance computing for real-time science"], "Total_Cost": ["EUR 3 760 793,75"], "Country": ["France", "United Kingdom", "Italy", "France"], "Project_ACR": ["greenFLASH"], "Technology_Description": "The main goal of Green Flash is to design and build a prototype for a Real-Time Controller (RTC) targeting the European Extremely Large Telescope (E-ELT) Adaptive Optics (AO) instrumentation. The E-ELT is a 39m diameter telescope to see first light in the early 2020s. To build this critical component of the telescope operations, the astronomical community is facing technical challenges, emerging from the combination of high data transfer bandwidth, low latency and high throughput requirements, similar to the identified critical barriers on the road to Exascale. With Green Flash, we will propose technical solutions, assess these enabling technologies through prototyping and assemble a full scale demonstrator to be validated with a simulator and tested on sky. With this R&D program we aim at feeding the E-ELT AO systems preliminary design studies, led by the selected first-light instruments consortia, with technological validations supporting the designs of their RTC modules. Our strategy is based on a strong interaction between academic and industrial partners. Components specifications and system requirements are derived from the AO application. Industrial partners lead the development of enabling technologies aiming at innovative tailored solutions with potential wide application range. The academic partners provide the missing links in the ecosystem, targeting their application with mainstream solutions. This increases both the value and market opportunities of the developed products. A prototype harboring all the features is used to assess the performance. It also provides the proof of concept for a resilient modular solution to equip a large scale European scientific facility, while containing the development cost by providing opportunities for return on investment.", "To": ["2018-09-30, ongoing project |"], "Meta": [""], "Topic_s": ["FETHPC-1-2014 - HPC Core Technologies, Programming Environments and Algorithms for Extreme Parallelism and Extreme Data Applications"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-10-01"], "Project_ID": ["671662"], "Call_for_Proposal": ["H2020-FETHPC-2014"]}, -{"Partners": ["THE FRANCIS CRICK INSTITUTE LIMITED"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["SIngle-cell multi-OMICs approach to study intra-tumour heterogeneity of soft tissue Sarcomas"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SIOMICS"], "Technology_Description": "Recently, multi-omics approaches have led to a plethora of publications describing in detail the \u2018omics landscapes of common cancer types. However, at the bulk tissue level, integrating different \u2018omics layers remains an uncompleted challenge. Soft tissue sarcomas are rare and often aggressive cancers of mesenchymal origin representing ~1% of all cancers but encompassing at least 50 subtypes. Hence, collecting enough of these rare samples for significant findings in a timely fashion is the biggest hurdle. This issue can be addressed by repeating observations within individual patients to generate new hypotheses. Our long-term collaboration aims to obtain the genome, transcriptome and methylome of each of 1,000 single-cells from 10 individual subtypes of soft tissue sarcomas. This design is possible thanks to DNA & RNA single-cell sequencing (SCS) of the same cell in Dr. Voet\u2019s lab, and bespoke computational analyses in Dr. Van Loo\u2019s lab, and access to this rare material of Prof. Flanagan, lead for the sarcoma component of the Genomics England 100,000 Genomes Project. This proposal is the pilot project, where we focus on one malignant peripheral nerve sheath tumour, a rare aggressive cancer originating from the connective tissues surrounding nerves. We will also sequence multiple regions of the primary tumour, the blood, and cell-free tumour DNA (ctDNA) before surgery and subsequently every three months. Prof. Flanagan\u2019s group will process the samples, and Dr. Voet will oversee the sequencing. In Dr. Van Loo\u2019s lab, I will develop the computational tools to uncover the 3 \u2018omics signals at the single-cell level that are averaged out in bulk tissues. SCS will shed light on the fundamental links between cancer genomic subclones and the transcriptional and epigenetic diversity of cancer cell types; and we will answer whether ctDNA reflects the diversity of cancer cells and how it evolves in the course of treatment.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations"], "From": ["2017-04-01"], "Project_ID": ["747852"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE GRENOBLE ALPES"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Digital Edition of the Roman de Florimont"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["DigiFlor"], "Technology_Description": "The project aims to produce a digital scholarly edition of an overlooked text of the vernacular European Middle Ages: the Roman de Florimont, composed by Aymon de Varennes (Lyon, 1188). The edition will be complemented by a methodological reflection on the feasibility of new digital tools versus the availability and applicability of existing ones with respect to medieval vernacular texts characterised by extreme linguistic variation. Indeed, Florimont has many unique characteristics, starting from its Mediterranean setting, bringing together into a single plot both the two main narrative strands of the 12-13th century, the Breton and the Antiquity cycles; the result is an original Southern version of the French chivalric roman. Furthermore, this thematic interest intersects with a remarkable linguistic relevance as the tradition includes witnesses related to two understudied linguistic domains: Franco-Proven\u00e7al (the third French language, together with the Langue d'Oil and the Langue d'Oc) and Franco-Italian (an artificial literary language). Despite this interest, Florimont has been almost entirely neglected by the scholarly community: only fifteen articles have been published on the subject and the only existing edition (Hilka\u2019s in 1932) is seriously flawed. The project will therefore produce an online multifaceted digital edition, exploiting existing tools for the support of stemmatics and linguistic analysis. Work on this text will then represent an opportunity to reflect on the scholarly status of the digital edition, which is revolutionizing the traditional concept of the edition in the context of Romance Philology. The multidisciplinary character of this research and the planned intensive training focused on Digital Humanities will allow the applicant to present herself to the academic world with a profile that is currently highly required but still not widely available: the Humanities researcher able to independently design and manage a DH project.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["745821"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITEIT UTRECHT"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["Teneurin interactions in the neuronal synapse"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["TEN-COMPLEX"], "Technology_Description": "Synapses, connections between neurons, are critical to the formation of neural circuits. Functional neural circuits control intricate processes such as learning and memory, whereas failure in neural circuitry formation can lead to developmental disorders including autism.", "To": ["2018-12-31, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["704070"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE", "THE REGENTS OF THE UNIVERSITY OF CALIFORNIA"], "EU_Contribution": ["EUR 269 857,80"], "Project_Title": ["States, firms and, sustainable economic growth: A view from the periphery"], "Total_Cost": ["EUR 269 857,80"], "Country": ["United Kingdom", "United States"], "Project_ACR": ["PERIGROWTH"], "Technology_Description": "Persistent socioeconomic cleavages between world-leading and late industrialising peripheral countries threaten the post-crisis recuperation and undermine the sense of solidarity necessary to address the world\u2019s most pressing challenges. Attenuating core-periphery asymmetries will be contingent on the ability of peripheral countries to generate sustainable economic growth, but there is no simple solution to achieve this. My project will address this challenge through a direct analysis of the productive and institutional structures of the two largest and most diversified peripheral economies, Spain and Korea, between 1985 and 2011. Using detailed case-studies of three industries based on a modified Global Value Chain methodology, the research will explore the character of state-firm interactions in these two countries and their role in shaping strategies for economic transformation as they upgraded from mid- to high-income economies. I will contend that upgrading in Spain and Korea was based on three factors: proactive states, coherent state structures, and symbiotic or co-dependent state-firm interactions. However, I will show that variations in the strategic and financial resources of state and firms, and in the influences of role-model countries, led Spain and Korea to pursue a different sectoral specialisation in complex services and manufacturing respectively. The research will be carried out at the University of California San Diego and the London School of Economics. The output will consist of a monograph and three academic papers. This project will enhance my career prospects by establishing me as an expert in economic transformation, expanding my publication record, developing my skills in international project management, and strengthening my international professional networks in the US and Asia. No less importantly, the results of the project will contribute to current European goals for smart, sustainable and inclusive growth.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["747943"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Philosophical Foundations of Topological Explanations"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["TOPEX"], "Technology_Description": "This project develops a philosophical account of a new kind of explanations that recently became prominent in neuroscience. On this approach, systems such as brain are represented as networks of their elements and their interactions. The explanation is then given in terms of features of connectedness (that is why it is called topological) of a network representing a system. ", "To": ["2018-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2016-06-01"], "Project_ID": ["703662"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6", "UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6", "OBSERVATOIRE DE PARIS"], "EU_Contribution": ["EUR 2 423 750"], "Project_Title": ["Exploring the outer solar system beyond Neptune using stellar occultations"], "Total_Cost": ["EUR 2 423 750"], "Country": ["France", "France", "France"], "Project_ACR": ["LUCKY STAR"], "Technology_Description": "The solar system beyond Neptune\u2019s contains largely unaltered material from the primordial circum-solar disk. It also kept the memory of the early planetary migrations, and thus contains essential information on the origin and evolution of our planetary system.", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-11-01"], "Project_ID": ["669416"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["THE UNIVERSITY OF LIVERPOOL", "THE UNIVERSITY OF LIVERPOOL", "Institute of Science and Technology Austria"], "EU_Contribution": ["EUR 1 820 865"], "Project_Title": ["Selective Barriers to Horizontal Gene Transfer"], "Total_Cost": ["EUR 1 820 865"], "Country": ["United Kingdom", "United Kingdom", "Austria"], "Project_ACR": ["EVOLHGT"], "Technology_Description": "Horizontal gene transfer (HGT) is a form of genic inheritance that occurs between individuals in a population or between species rather than from parent to offspring. HGT is most prevalent in bacteria, where it is an important source of novel metabolic pathways, pathogenicity factors, and antibiotic resistance.", "To": ["2020-05-31, ongoing project |"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-06-01"], "Project_ID": ["648440"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["INSTITUTE OF MATHEMATICS AND INFORMATICS AT THE BULGARIAN ACADEMY OF SCIENCE"], "EU_Contribution": ["EUR 128 994"], "Project_Title": ["Spectral Theory of Non-Selfadjoint Markov Processes with Applications in Self-Similarity, Branching Processes and Financial Mathematics"], "Total_Cost": ["EUR 128 994"], "Country": ["Bulgaria"], "Project_ACR": ["MOCT"], "Technology_Description": "The project contextually sets up a novel framework to study the spectral-theoretical properties of classes of non-selfadjoint (NSA) operators related to Markov processes (MP) via their intertwining to a continuous path selfadjoint (SA) MP. Conceptually, this means that the jumps of each class of NSA MP can be considered a perturbation of one SA MP realized by an intertwining kernel. This approach can have far-reaching consequences for understanding classes of MP as the reduction to SA MP leads to well-studied objects whereas the spectral theory of NSA operators is far from understood. The price of that is the non-invertability of the intertwining kernels. This framework is explored and crystallized by a challenging, detailed spectral-theoretical study of an enormous class of NSA operators directly arising from the key phenomenon of self-similarity and in duality from branching. This is achieved by a synergy of research fields complementing each other to obtain the spectral properties of those operators culminating in the derivation of spectral expansions of the generated semigroups. As a result of this synergy, a number of tools and techniques with impact, including applications to fields beyond the scope of the project, are derived. A particular development in the area of recurrent equations and special functions will be unexpectedly exploited to the effect of a comprehensive theoretical and applied study, including numerical schemes, of key quantities in financial and insurance mathematics such as Asian options and perpetuities. A training-through-research in line with the fellow\u2019s affiliation to the host institution and the proposed secondment will critically contribute to the optimal completion of the proposal in terms of time, scope and quality.", "To": ["2017-06-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Bulgaria"], "Activity": ["Research Organisations"], "From": ["2015-07-01"], "Project_ID": ["657025"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITA CA' FOSCARI VENEZIA"], "EU_Contribution": ["EUR 168 277,20"], "Project_Title": ["Sparse Composite Likelihood Inference in Count Time Series"], "Total_Cost": ["EUR 168 277,20"], "Country": ["Italy"], "Project_ACR": ["SCouT"], "Technology_Description": "The availability of many interesting datasets consisting of count time series has motivated a steadily increasing research activity towards the development of appropriate statistical models. Nowadays, a variety of time series models constructed on the basis of the integer-valued property of count data is available. However, their practical usefulness is often limited because of difficulties to implement efficient estimation procedures. These difficulties grow significantly when higher-order autoregressive and moving average terms are included in the model or when multivariate time series data are considered. The SCouT project aims to enhance the flexibility of time series models for counts and facilitate their application to data characterized by complex dependence structures. To this end, the SCouT project proposes an innovative methodological approach that integrates two powerful statistical tools, that is sparsity techniques and composite likelihood methods. The project will provide a unified framework for simultaneous order selection and estimation of autoregressive and moving average terms in count time series models, reducing considerably the computational burden of traditional model selection approaches and improving the predictive performance of the fitted model. The potential of the suggested methodology will be further highlighted by investigating its extensions to spatial and spatio-temporal data that are usually characterized by complex dependence structures. Such data are often met in the field of temporal and spatial analysis of public health surveillance data that will be the main application field of the project. The simultaneous order selection and estimation procedure established by the SCouT project will offer great support to statistical methods for public health surveillance and significantly contribute to the achievement of the effective and timely detection of disease outbreaks.", "To": ["2018-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["699980"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["REGULATION OF NEURONAL GENE EXPRESSION THROUGH CHROMOSOME ARCHITECTURE"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["NGECA"], "Technology_Description": "A remarkable feature of the brain is its ability to adapt to changing environmental conditions. Modulation of synaptic strength and neuronal circuitry underlies experience-dependent learning, and requires widespread changes in gene expression. Following neuronal depolarisation, intracellular signalling results in rapid induction of many activity-regulated genes (ARGs). There are numerous interconnected levels of gene regulation; one critical aspect relates to the three-dimensional conformation of chromosomes within the nucleus. Looping of genes to regulatory regions and to other genes is required for transcriptional activation in other cell types, but remains largely unexplored in neurons. In this proposal, I will investigate how the genome architecture changes during neuronal depolarisation, and how this influences activity-induced transcription and neuronal plasticity. I will first map the genomic interactions of ARGs in neurons before and after depolarisation. This experimental approach will allow identification of enhancer-promoter loops and multi-gene complexes in an unbiased manner. Single-cell imaging studies will be performed to quantify the frequency of interactions across individual neurons. I will use super-resolution microscopy to simultaneously analyse multiple loci with high precision, providing unprecedented detail of gene interactions in response to neuronal activity. Finally, I will use genome editing to disrupt specific chromosomal contacts and evaluate the transcriptional induction of associated genes. I will assess whether loss of genomic contacts affects dendritic growth, a process associated with neuronal plasticity and dependent on ARG induction, to understand the biological implications of chromosome looping. The aim of this project is to discover novel molecular mechanisms that govern transcription during neuronal activation, which is critical in experience-dependent learning.", "To": ["2018-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-11-01"], "Project_ID": ["702327"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["FONDATION NATIONALE DES SCIENCES POLITIQUES"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Lobbying and framing in foreign policy. EU and member states\u2019 foreign policies towards Israel and Palestine"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["LOBFRAM"], "Technology_Description": "LOBFRAM aims to advance our understanding of lobbying and framing in foreign policy in the European Union\u2019s (EU) system of multi-level governance. While lobbying in the EU has received a lot of attention in recent years, lobbying in foreign policy remains a largely under-researched topic. Therefore, this project will explore the activities of non-state actors (NSAs), such as business groups, NGOs and solidarity movements, in EU foreign policy, investigating the networks that are established at different levels (EU and member states) and framing processes. The main contribution of LOBFRAM will be to investigate networks as transmitters of ideas. In turn, this will help us to analyse how frames are created, get codified and become collective frames influencing foreign policy at both the EU and member state levels, as well as what mechanisms of mutual interaction exist between EU and national foreign policy positions.", "To": ["2018-02-23, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["657949"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Mineral weathering in the unsaturated zone from the molecular to macro scale"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["DryMIN"], "Technology_Description": "\"\"Mineral weathering in the unsaturated zone from the molecular to macro scale (DryMIN)\"", "To": ["2019-01-22, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-01-23"], "Project_ID": ["701478"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["CONSIGLIO NAZIONALE DELLE RICERCHE", "CONSIGLIO NAZIONALE DELLE RICERCHE", "UNIVERSITA DEL SALENTO", "SCUOLA NORMALE SUPERIORE"], "EU_Contribution": ["EUR 1 993 908"], "Project_Title": ["4-Dimensional printing for adaptive optoelectronic components"], "Total_Cost": ["EUR 1 993 908"], "Country": ["Italy", "Italy", "Italy", "Italy"], "Project_ACR": ["xPRINT"], "Technology_Description": "This project aims at developing four-dimensional printing of new adaptive systems, namely printing of complex, three-dimensional polymer objects embedding functional compounds and able to change or adapt their physical properties responding to environmental stimuli. Additive manufacturing of three-dimensional objects relies on depositing or curing materials in a layer-by-layer fashion, starting from computer assisted design. These technologies have rapidly evolved from laboratory research to commercially available desktop systems, with costs decreasing continuously. Notwithstanding such astonishing progress, the potentialities of three-dimensional printing are still poorly exploited in terms of both materials and process resolution. This project will shed new light on the fundamental aspects of three-dimensional polymerization, thus establishing new process design rules and predictive tools for printing resolution. It will also specifically engineer additive manufacturing for printing materials embedding active compounds, thus leading to real four-dimensional objects, namely structures that have three-dimensional features and time-changing physical properties at the same time. An integrated approach will be pursued to this aim, where modeling and process engineering will be complemented by process monitoring, in order to establish well defined and reproducible methods for four-dimensional printing of photonic structures. The operation of the adaptive components, for optical computing and data storage, will be based on their nonlinear response to optical inputs. Leading to a new and pioneering laboratory on four-dimensional printing technologies, this project will critically consolidate scientific independence.", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["682157"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["OBSERVATOIRE DE PARIS"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["UNVEILING THE NATURE OF PRIMORDIAL STARS"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["PRIMORDIAL"], "Technology_Description": "\"Understanding the nature of the first stars is a fundamental problem in Cosmology and Galaxy Formation. Numerical simulations suggest that primordial stars were more massive that present-day stars, and so they rapidly disappeared. Heavy elements newly produced by these stars enriched the surrounding gas, out of which long-lived, low-mass stars formed. These \"second-generation\" stars survive until present-day, preserving in their photospheres the chemical imprint of the first stars. In the Local Group, high-resolution spectroscopic studies, offer us the unique opportunity to reveal these fossil signatures. But second-generation stars are extremely rare, making their detection challenging.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["700907"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Gemination Harmony"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["GeHa"], "Technology_Description": "The goal of this project is to investigate long-distance anticipatory effects from word-medial geminates across three unrelated languages \u2013 Italian, Tashlhiyt Berber and Japanese. In particular, it examines whether defining- and enhancing- features associated with geminates are already anticipated on the non-adjacent word-initial consonant (e.g., whether in the Italian [palla] \u201cball\u201d the properties of the word-medial [ll] geminate are already foreshadowed on the word-initial [p]). In relation to the geminate-singleton distinction, Italian, Tashlhiyt Berber and Japanese present similarities (e.g. duration of the word-medial geminate consonant as primary correlate) and differences that are relevant for testing the following issues a) the type of length-related vs. strength-related properties that are spread from the word-medial geminate to the word-initial consonant; b) the domain of the harmonic process, and more precisely, the role played by the intervening vowel (e.g. the [a] in [palla]). In addition to the language factor, long-distance anticipatory effects induced by geminates will be tested against segmental factors (i.e. type of word-medial geminate consonant), prosodic factors (i.e. focus) and performance-related factors (i.e. speech rate). Two acoustic and articulatory experiments (measurements of tongue-to-palate contact and intraoral pressure) will be designed to address these issues. The main contribution of this project lies in determining the articulatory and acoustic bases of harmony as induced by gemination (\u2018gemination harmony\u2019) within a cross-linguistic perspective. As such, it may provide important insights into the interplay between phonetics and phonology and have crucial implications for the understanding of long-distance effects in speech production.", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2015-09-01"], "Project_ID": ["661530"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE UNIVERSITY OF WESTMINSTER LBG", "THE UNIVERSITY OF WESTMINSTER LBG"], "EU_Contribution": ["EUR 1 497 212"], "Project_Title": ["MONSOON ASSEMBLAGES"], "Total_Cost": ["EUR 1 497 212"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["MONASS"], "Technology_Description": "The ambition of this cutting edge research project is to deliver a ground breaking, interdisciplinary design-driven inquiry into the impacts of changing monsoon climates in three of South Asia\u2019s rapidly growing cities. This will be undertaken at a time when climate change and urban development conspire to produce unlikely futures for urban survival. Extreme weather events, all attributed to the monsoon\u2019s capricious nature, are resulting in increasing frequency in water shortages, power failures, floods, out-breaks of disease, damage to property and loss of life. In responding to these events, the project will challenge the dominant view of the monsoon as a natural meteorological system outside of and distinct from society. Instead it will propose that the monsoon is a co-production of physical and social dynamics entangled within historic lived environments that can be analyzed, worked with, shaped and changed. To do so, an unconventional interdisciplinary team will develop a novel research methodology around the new operative concept of \u2018monsoon assemblages.\u2019 This will bring together the spatial design disciplines with the environmental humanities to advance research of lived environments as indivisibly natural, social and political and to propose models for intervening in them through design. ", "To": ["2021-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["679873"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["KATHOLIEKE UNIVERSITEIT LEUVEN", "UNIVERSITAT POLITECNICA DE VALENCIA"], "EU_Contribution": ["EUR 100 000"], "Project_Title": ["Distributed Network of Active Noise Equalizers for Multi-User Sound Control"], "Total_Cost": ["EUR 130 937,50"], "Country": ["Belgium", "Spain"], "Project_ACR": ["D-Noise"], "Technology_Description": "The project is aimed at developing a novel wireless acoustic sensor network (WASN) for multi-user active noise equalization without the need of using headsets. This system is formed by multiple active noise equalizers (ANEs), which act as a node in a WASN-type set up and cooperate to simultaneously solve their node-specific noise equalization problems. By doing so, the proposed system can simultaneously ensure the auditory comfort of multiple users that are regularly exposed to high noise levels. This is radically different from the current multi-user systems for ANE where each node aims at ensuring the auditory comfort of each passenger without cooperation.", "To": ["2018-10-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-04-2016-2017 - FET Innovation Launchpad"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["754576"], "Call_for_Proposal": ["H2020-FETOPEN-4-2016-2017"]}, -{"Partners": ["ISTANBUL TEKNIK UNIVERSITESI"], "EU_Contribution": ["EUR 145 845,60"], "Project_Title": ["Deep Learning UAV Networks for Autonomous Forest Firefighting"], "Total_Cost": ["EUR 145 845,60"], "Country": ["Turkey"], "Project_ACR": ["DUF"], "Technology_Description": "Thousands of hectares of forest lands are lost to wildfires every year. Utilization of Unmanned Aerial Vehicles (UAVs) is an efficient tool for fighting fires, however the state-of-the-art techniques lack in ability to predict fire spread direction and coordinate multiple UAVs to suppress the fire under limited communication. DUF project aims to apply powerful tools from artificial intelligence domain to UAV firefighting problem, creating an innovative solution for autonomous firefighting, which will reduce the amount of lands lost to fires. DUF will use the deep learning techniques for estimating the fire spread direction from infrared camera streams obtained from UAVs. Deep learning is a mature technology for classical image recognition, but the use of deep learning to learn predictive models for fire spread is a novel approach. After the model is learned, a decentralized approximate dynamic planning algorithm will be utilized to coordinate UAV actions for suppressing the fire. The algorithm development, simulations and first phase of the flight experiments will be conducted at Istanbul Technical University (ITU) Aerospace Research Center (ARC). The project will conclude with flight tests conducted on natural forest fires, with operational support from Forest of Ministry of Turkey. Prof. Ure earned his Ph.D. degree from Massachusetts Institute of Technology, working on advanced UAV projects and collaborating with leading researchers in the world. He has extensive experience on autonomous systems and published more than 30 critically acclaimed journal and conference papers in this subject. Prof. Ure is currently working as assistant professor in ITU and through this innovative multidisciplinary research and with the help of experimental infrastructure provided by the ITU, Prof. Ure is expected to gain maturity in managing research projects and advance his career toward being an esteemed professor in the field of aeronautics and artificial intelligence in Europe.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Turkey"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["752669"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAET SIEGEN", "UNIVERSITAET SIEGEN"], "EU_Contribution": ["EUR 1 673 875"], "Project_Title": ["Temporal Quantum Correlations"], "Total_Cost": ["EUR 1 673 875"], "Country": ["Germany", "Germany"], "Project_ACR": ["TempoQ"], "Technology_Description": "Correlations are central for our modern view on the foundations of quantum theory and applications like quantum information processing. So far, research concentrated on correlations between two or more particles. Indeed, for this situation it is well established that spatial quantum correlations are a useful resource for tasks like quantum cryptography and quantum metrology. There are, however, other types of correlations in quantum mechanics, which arise if a sequence of measurements on a single quantum system is made. These temporal quantum correlations have recently attracted attention, because they are central for the understanding of some differences between the quantum and the classical world. Moreover, due to experimental progress their observation has become feasible with trapped ions, polarized photons, or other quantum optical systems.", "To": ["2021-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["683107"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["CENTRUM ASTRONOMICZNE IM. MIKOLAJAKOPERNIKA POLSKIEJ AKADEMII NAUK", "CENTRUM ASTRONOMICZNE IM. MIKOLAJAKOPERNIKA POLSKIEJ AKADEMII NAUK", "OBSERVATOIRE DE PARIS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSIDAD DE CONCEPCION"], "EU_Contribution": ["EUR 2 360 500"], "Project_Title": ["A sub-percent distance scale from binaries and Cepheids"], "Total_Cost": ["EUR 2 360 500"], "Country": ["Poland", "Poland", "France", "France", "Chile"], "Project_ACR": ["CepBin"], "Technology_Description": "We propose to carry out a project which will produce a decisive step towards improving the accuracy of the Hubble constant as determined from the Cepheid-SN Ia method to 1%, by using 28 extremely rare eclipsing binary systems in the LMC which offer the potential to determine their distances to 1%. To achieve this accuracy we will reduce the main error in the binary method by interferometric angular diameter measurements of a sample of red clump stars which resemble the stars in our binary systems. We will check on our calibration with similar binary systems close enough to determine their orbits from interferometry. We already showed the feasibility of our method which yielded the best-ever distance determination to the LMC of 2.2% from 8 such binary systems. With 28 systems and the improved angular diameter calibration we will push the LMC distance uncertainty down to 1% which will allow to set the zero point of the Cepheid PL relation with the same accuracy using the large available LMC Cepheid sample. We will determine the metallicity effect on Cepheid luminosities by a) determining a 2% distance to the more metal-poor SMC with our binary method, and by b) measuring the distances to LMC and SMC with an improved Baade-Wesselink (BW) method. We will achieve this improvement by analyzing 9 unique Cepheids in eclipsing binaries in the LMC our group has discovered which allow factor- of-ten improvements in the determination of all basic physical parameters of Cepheids. These studies will also increase our confidence in the Cepheid-based H0 determination. Our project bears strong synergy to the Gaia mission by providing the best checks on possible systematic uncertainties on Gaia parallaxes with 200 binary systems whose distances we will measure to 1-2%. We will provide two unique tools for 1-3 % distance determinations to individual objects in a volume of 1 Mpc, being competitive to Gaia already at a distance of 1 kpc from the Sun.", "To": ["2021-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Poland"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2016-11-01"], "Project_ID": ["695099"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI PADOVA", "UNIVERSITA DEGLI STUDI DI PADOVA", "CONSIGLIO NAZIONALE DELLE RICERCHE"], "EU_Contribution": ["EUR 1 432 890"], "Project_Title": ["a Theoretical chemistry Approach to tiME-resolved molecular Plasmonics"], "Total_Cost": ["EUR 1 432 890"], "Country": ["Italy", "Italy", "Italy"], "Project_ACR": ["TAME-Plasmons"], "Technology_Description": "Ultrafast spectroscopy is a powerful tool able to disclose the atomistic real-time motion picture of the basic chemical events behind technology and Life, such as catalytic reactions or photosynthetic light harvesting. Nowadays, by cleverly harnessing the interaction of the studied molecules with plasmons (collective electron excitations supported, e.g., by metal nanoparticles) it is becoming possible to focus these investigations on specific nanoscopic regions, such as a portion of a catalytic surface or of a photosynthetic membrane. This coupling can also produce new quantum effects such as molecule-plasmon hybrid excitations. On the other hand, it makes the real-time molecular evolution and its perturbation by light more complex, and thus calls for new theoretical treatments. The available ones are unable to tackle this complexity, because they consist of phenomenological models focused on field enhancements or on generic features of the various plasmon-molecule coupling regimes. The goal of TAME-Plasmons is to develop a theoretical chemistry approach to directly simulate the real time evolution of molecules interacting with plasmons and light. Our approach lifts the current theoretical limitations by coupling a real-time quantum chemical description of the molecules with a time-dependent electromagnetic description of plasmons, rooted in our previous work on steady-state molecular plasmonics. We will implement this approach in an open-source software, accessible also to non-specialists. We will address current open issues such as the controversial nature of plasmon-aided frequency up-conversion by noble gases and the interpretation of sub-molecularly resolved photoemission induced by scanning tunneling microscopy. We will also anticipate questions that may arise along with progress in the field, for example how to engineer energy transfer paths in photosynthetic light harvesting proteins by exploiting the coupling to plasmons.", "To": ["2021-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2016-04-01"], "Project_ID": ["681285"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["UNIVERSITY OF LEEDS"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Applying risk communication strategies to reduce speeding-related risks"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["Speedingrisk"], "Technology_Description": "In the EU, road accidents are in the top three causes of deaths and hospitalizations . WHO finds it crucial to discourage speeding, because it is a main cause of road accidents. The Fellow\u2019s research in the psychology of human factors engineering shows that people underestimate the risks of accidents from speeding and overestimate how much time is saved through speeding. Public campaigns have typically not yet sought to correct these misunderstandings but rather have focused on emotional fear-appeals to reduce speeding. The Supervisor\u2019s work on risk communication provides a systematic method for correcting such decision-relevant beliefs, which has been successfully applied to a variety of contexts, but not to the design of dashboard tools. We take the novel approach of combining the Fellow\u2019s and Supervisor\u2019s fields to design dashboard tools and public campaigns that discourage intentions to speed by correcting drivers\u2019 misunderstandings of the risks and benefits of speeding. This project will benefit from Fellow's experience in leading projects on informing driver perceptions with dashboard tools, and her ongoing partnerships with the car industry and governmental agencies. The project will lead to knowledge transfer between the Fellow\u2019s Swedish Transportation Institute, partners at Volvo Cars and government agencies as well as the Supervisor\u2019s Centre for Decision Research and the associated Institute for Transport Studies at the University of Leeds (UK). The project will boost the Fellow\u2019s academic career progression, as she aims to become a world-leading expert in evidence-based interventions that improve driver safety and save drivers\u2019 lives.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["706553"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN"], "EU_Contribution": ["EUR 248 063,40"], "Project_Title": ["Systematic search of RegulAtory elements coNtrOlling autosomal Monoallelic expression"], "Total_Cost": ["EUR 248 063,40"], "Country": ["Ireland"], "Project_ACR": ["RANdOM"], "Technology_Description": "Autosomal monoallelic expression (MAE) is an epigenetic phenomenon that controls the relative expression of maternal and paternal alleles in thousands of mammalian genes. Despite MAE\u2019s widespread character the molecular mechanisms involved in its establishment and maintenance are yet to be clarified. Recent work shows that the sets of genes subject to MAE are highly consistent across individuals and conserved between human and mouse species. I propose to test that such conservation is due to specific regulatory elements in the genome associated with MAE genes. The strategy to discover such elements is via a systematic analysis of differences in genome-wide MAE patterns. In the outgoing phase of the Fellowship, I will be based in DFCI under the supervision of Prof. A. Gimelbrant. There, I will experimentally map MAE patterns in mice with highly divergent genomic backgrounds and identify loci that consistently differ between strains in whether they are MAE. Using computational methods, I will then determine whether particular motifs are associated with such variable regions. I will further assess the role of the candidate regulatory elements using specific F1 crosses and targeted mutagenesis. The analysis in the mouse will be complemented by comparative analysis of human and chimp matched cells, in order to narrow down the candidate loci list and shed light on the evolution of MAE. Successful completion of this project will establish the first model of genetic control of MAE and open doors to progress in the mechanistic and developmental understanding of MAE. On return to the TCD, under the supervision of Prof. A. McLysaght, I will be the link between two laboratories with a diverse research focus that would not be collaborating unless in the context of this Fellowship. I will emerge from this collaborative work with new skills commensurate with a leading independent researcher in the EU.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["752806"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE"], "EU_Contribution": ["EUR 187 419,60"], "Project_Title": ["Advanced In-situ Techniques for the Development of Metal Oxide Nanostructures."], "Total_Cost": ["EUR 187 419,60"], "Country": ["Switzerland"], "Project_ACR": ["NanoAID"], "Technology_Description": "Complex metal oxides (MO) are the center of interest in a range of fields, with one of the most exciting applications being artificial photosynthesis. Converting solar energy into chemical bonds, once perfected, might constitute a large part of a solution to the energy sustainability problem modern society faces. Semiconductor MOs have been shown to be promising candidates for light absorbers in anodes of photoelectrochemical cells used for water cleavage and hydrogen production from sunlight. Candidate materials with optimal band gap and band alignment with water redox level used in such devices are often selected based on combinatorial material science techniques (inkjet printing, co-sputtering) and theoretical calculations. Once a compound is identified as having promising photoelectrochemical properties, a fabrication route is sought to prepare nano-structured thin films. Colloidal chemistry is a highly promising approach for the synthesis of complex MO nano crystals (NCs), in principle allowing control over the size and structure of the NCs by choosing appropriate precursors and tuning the conditions (temperature, time, reagent concentration, organic ligands). These advancements greatly facilitate research in the field of complex functional materials and are now a standard, but the optimization of synthesis-by-design of NCs and thin films fabrication has been lacking and mainly based on a trial and error approach. With NanoAID we will address this important issue and develop a comprehensive toolbox for synthesis and characterization of complex oxides, which will go beyond the state of the art with precise defects and non-stoichiometry control capabilities. NanoAID will focus on developing a toolbox for rapid structural and morphological characterization of complex oxide NCs and thin films, and thermodynamic analysis of the involved compounds. Research will center on ternary and quaternary compounds, namely Cu/Mn-V-O.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["753124"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["Epigenetic regulation of cardiac regeneration after injury."], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["HeartATAC"], "Technology_Description": "Cardiovascular disease is a leading cause of morbidity and mortality worldwide, and there is a constant and urgent need for novel, more effective therapies to treat it. Chronic tissue hypoxia, nutrient deprivation and myocardial cell death are some of the factors contributing to ischemic heart disease (IHD), the most common cause of death from all cardiovascular diseases. Current therapeutic approaches are limited in their capacity to enhance cardiac regeneration after injury. Toward novel selective therapies, it is important to gain a detailed understanding of pathways orchestrating cardiomyocyte proliferation during development and after injury.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Netherlands"], "Activity": ["Research Organisations"], "From": ["2017-07-01"], "Project_ID": ["751988"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSIDAD DE ZARAGOZA"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Nanoparticle-based immunization, a novel therapeutic strategy for amyotrophic lateral sclerosis"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["NanoALS"], "Technology_Description": "As the life span of the population extends, the prevalence of neurodegenerative diseases is rapidly increasing representing a considerable impact for the quality of life and economy of many countries worldwide. Most of these diseases, including Amyotrophic lateral sclerosis (ALS) are currently considered as proteopathies, where some proteins (SOD1 in the case of ALS) adopt misfolded conformations prone to aggregate and cause cellular toxicity and motor neuron death. Moreover, these proteins are secreted to extracellular media contributing to the widespread of the disease in a prion-like manner, by acting as scaffolds for the misfolding of endogenous proteins when uptaken by surrounding cells. The aim of NanoALS is to bring together Neuro and Nanoscience fields to design a novel passive immunization therapy to target the misfolded SOD1 released into cerebrospinal fluid in ALS. It will be based on the systemic delivery of gold and PLGA nanoparticles functionalized with specific antibodies against the different isoforms of misfolded SOD1. These nanoconstructs will bind the different aberrantly folded SOD1 forms preventing their reuptake by neighbouring cells and blocking the cytotoxic epitopes exposed after misfolding. The multidisciplinary work program in NanoALS covers the synthesis of the functionalized nanoconstructs as well as validation of their therapeutic potential in neuronal cell lines and in the SOD1-G93A mouse model of ALS. Immunization against misfolded extracellular proteins has showed an encouraging success in ALS mouse models and in recent clinical trials with Alzheimer patients. Optimizing the delivery systems and targeting different misfolded isoforms as well as the active exploitation and dissemination strategy designed for NanoALS will maximize the benefits of these therapies both in ALS and other proteopathies.", "To": ["2020-02-29, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["752349"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KOZEP-EUROPAI EGYETEM"], "EU_Contribution": ["EUR 134 239,20"], "Project_Title": ["Migration Solidarity and Acts of Citizenship along the Balkan Route"], "Total_Cost": ["EUR 134 239,20"], "Country": ["Hungary"], "Project_ACR": ["MigSol"], "Technology_Description": "The aim of this 24-month Fellowship is to explore how refugees and refugee solidarity groups along the \u201cBalkan route\u201d relate to and enact European citizenship. While the project of European citizenship is an unprecedented political development, it has institutionally been modelled upon and reproduces national conceptualisations of citizenship, rights and identity. The research will undertake a comparative analysis of discourses and practices of refugees and pro-refugee volunteers in both EU and non-EU sites, and of the way in which they challenge concepts and institutions of European citizenship derived from national models of membership. It will pay particular attention to the relationship between \u201cmovement\u201d and the constitution of new European political subjectivities. The main objectives of this study are (1) to engage in a critical examination of the processes and institutions of European citizenship with a specific focus on countries of the \u201cBalkan route\u201d; (2) to develop a cross-national and cross-local perspective on solidarity practices with refugees that have emerged along the Balkan route; (3) to investigate \u201cacts of citizenship\u201d emerging from both EU and non-EU citizens in relation to refugee mobilities and to assess their implication for European citizenship; (4) To develop analytical and theoretical frames to reflect on new politics of solidarity in Europe and the way in which they contest exclusionary readings of Europe; and (5) to contribute to conceptual debates on citizenship, the governance of migration and social movements and solidarity in the EU and beyond. In the current context of uncertainty regarding the future of the EU, these questions appear of rising urgency. This study proposes to address these issues through ethnographic research with a range of pro-refugee initiatives in Hungary, Serbia and Greece, three countries at the heart of the Balkan route yet which hold different historical and political relationships to \u201cEurope\u201d and the EU.", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Hungary"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["751866"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSIDAD DE BURGOS"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["High throughput computing for accelerated photovoltaic material discovery: From materialdatabase to the new generation of photovoltaic materials."], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["HT PHOTO DB"], "Technology_Description": "This proposal combines synergistically the predictive power of quantum mechanical calculations with a high throughput framework for the accelerated photovoltaic material discovery. The main objective of the project is the creation of a material database that contains no crystalline-complex materials, which can be potential candidate for the development of a new generation of photovoltaic material. The robustness of the project is reinforced by the secondment of Onyx solar which will synthesis and characterize the most promising candidates to validate the methodology and optimize the process. The collaboration between ICCRAM researchers and facilities and the experience of the fellow in this multidisciplinary field guarantee the ideal conditions for the success of the research and the development of new methodologies, infrastructures and knowledge that are highly linked to the roadmap described in Horizon 2020.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["752608"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["VALSTYBINIS MOKSLINIU TYRIMU INSTITUTAS FIZINIU IR TECHNOLOGIJOS MOKSLU CENTRAS"], "EU_Contribution": ["EUR 142 779,60"], "Project_Title": ["Graphene-Manganite Nanostructures for Novel Pulsed Magnetic Field Sensors"], "Total_Cost": ["EUR 142 779,60"], "Country": ["Lithuania"], "Project_ACR": ["GRAMAS"], "Technology_Description": "A two-way innovative approach of combining Graphene and novel La1-xSrxMn1-yCoyO3 manganite is proposed in this GRAMAS project in order to manufacture highly sensitive sensors, measuring pulsed magnetic field [0.5 \u2013 60 T] independently on its direction (so-called B-scalar sensors). Firstly, the Co3+ cations will be introduced into the Mn3+ sites in order to achieve a novel, nanostructured La1-xSrxMn1-yCoyO3 layers deposited on various substrates by MOCVD technique. Secondly, the single/few-layers of Graphene will be transferred on the top of Co-doped manganite layers, since Graphene has a superior mobility of charge carriers which also increases the Magnetoresistance. In addition, Graphene layer will allow indication of magnetic field direction respectively to manganite B-scalar sensors\u2018s plane. Moreover, the combination of manganite/Graphene is expected to open new potentials for the discovery of superior magnetotransport properties even at room temperatures and increased sensitivity to magnetic field. ", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["Lithuania"], "Activity": ["Research Organisations"], "From": ["2017-04-01"], "Project_ID": ["751905"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["EARLHAM INSTITUTE", "EARLHAM INSTITUTE", "THE SAINSBURY LABORATORY"], "EU_Contribution": ["EUR 1 499 997"], "Project_Title": ["Mechanisms of Immune Receptor Diversification in Cereals"], "Total_Cost": ["EUR 1 499 997"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom"], "Project_ACR": ["MIREDI"], "Technology_Description": "The plant immune system is innate \u2013 it is encoded in the germline. In natural pathosystems, plants efficiently deploy hundreds of immune receptors to detect and disarm rapidly evolving pathogens including viruses, bacteria, nematodes, insects, fungi and oomycetes. Exactly how such receptor diversity can evolve is an elusive question with important practical ramifications. A central class of plant immune receptors, called Nucleotide Binding Leucine Rich Repeats proteins (NLR), has been implicated in recognition of vastly diverse pathogen-derived effector molecules. An emerging paradigm of receptor diversification in plant genomes involves new gene fusions of receptors with host proteins that are normally targeted by pathogen effectors. Such fusion receptors \u2018bait\u2019 pathogens and their integrated domains are thought to function as \u2018decoys\u2019 or \u2018sensors\u2019 that mediate pathogen recognition. I have recently demonstrated that the mechanism of generating new receptors through gene fusions originated at least 500 million years ago in mosses and is common to all flowering plants. Here, I propose to decode the mechanisms of plant immune receptor diversification by gene fusions by studying diversity and functions of immune receptors in grasses, a young highly diversified plant family that includes the three most important crops: maize, rice and wheat. My specific aims are to: ", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations", "Research Organisations", "Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["716233"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["INSTITUTO VALENCIANO DE INVESTIGACIONES ECONOMICAS, S.A."], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Baltic Countries Capital, Labour, Energy, Material and Service inputs"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["BALTIC KLEMS"], "Technology_Description": "The BALTIC KLEMS (Baltic Countries Capital, Labour, Energy, Material, Service inputs) project aims at developing methodology for the Baltic Countries for KLEMS (countries are missing information). It expands the actual EU KLEMS and WORLD KLEMS framework and includes the role played by detailed intangible assets to productivity growth. The results obtained will enable: a) to up-to-date information in the EU KLEMS database; b) to perform comparative economic analysis for different developed countries from two complementary perspectives: the determinants of productivity growth and the patterns of structural change; c) be beneficial for a set of EU countries (plus the USA) from the INTAN-Invest initiative as well as from the SPINTAN project funded by the 7th Framework programme of the EU. This can be summarized in the following objectives: (1) to investigate the economic structures; (2) to group the countries and propose a taxonomy of consistent patterns; (3) to develop a new methodology; (4) to investigate the main characteristics of detailed intangible capital impact on productivity growth; (5, 6) to measure, rank the detailed contributors; (7, 8, 9) to derive the main results emphasizing the main policy implications. In order to achieve these goals WP1 is dedicated to researching the economic structures. WP2 is devoted to developing a methodology, to obtaining values, ranking. WP3 is dedicated to identifying the consistent paths of structural changes and the determinants. WP4 is dedicated to dissemination, public engagement. WP5 is dedicated to the practical exploitation. WP6 is dedicated to the management. WP7 is dedicated to training, career development. The researcher had internship at the host supervised during the doctoral studies. The supervisor is the coordinator of the SPINTAN project funded by the 7th Framework programme. The host performs the calculations for the case of Spain (EU KLEMS), a set of Latin American countries (LA KLEMS, a part of WORLD KLEMS).", "To": ["2019-09-17, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-SE - Society and Enterprise panel"], "Coordinated_in": ["Spain"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-09-18"], "Project_ID": ["751198"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE LIBRE DE BRUXELLES"], "EU_Contribution": ["EUR 258 530,40"], "Project_Title": ["Blockchain: a new framework for swarm RObotic Systems"], "Total_Cost": ["EUR 258 530,40"], "Country": ["Belgium"], "Project_ACR": ["BROS"], "Technology_Description": "Swarms of robots will revolutionize many industrial applications, from targeted material delivery to precision farming. However, the characteristics that make them ideal for certain future applications \u2014robot autonomy, decentralized control, collective emergent behavior, etc.\u2014 can also be an obstacle when transferring this technology from academic institutions to real-world problems. Blockchain, an emerging technology originating in the Bitcoin field, demonstrates that by combining peer-to-peer networks with cryptographic algorithms a group of agents can reach an agreement on a particular state of affairs without the need for a controlling authority. Using a novel combination of blockchain technology and swarm robotics systems, BROS will generate new models to address three fundamental issues by using the robots as nodes in a network and encapsulating their transactions in blocks: First, new security models and methods can be implemented in order to give data confidentiality and entity validation to robot swarms, therefore making them suitable for trust-sensitive applications. Second, distributed decision-making and collaborative missions can be easily designed, implemented, and carried out by using special transactions in the blockchain, which enable robotic agents to vote and reach agreements. Third, robots may be able to function in diverse and changing environments without any change in their control algorithm, if their operation corresponds to different blockchains that use different parameters. In the initial stage, blockchain technology will be used as a main control plane in combination with novel large-scale robot simulation tools such as ARGoS. Finally, the feasibility of the models obtained under the previous objective will be validated in real-robot swarms, outputting a prototypical system that can serve as initial step towards transferring the proposed techniques from the academia into the industry.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["751615"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ELVESYS SAS"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Fully Integrated Technology based on quantitative polymerase chain reaction for the diagnosis of Urinal Tract Infection"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["FIT-UTI"], "Technology_Description": "The project aims at developing a low-cost and reliable microfluidic disposable chip and the corresponding plug-and-play operating system for fast point-of-care diagnosis of UTI (Urinary Tract Infection) disease. This project will make the best of the competences of the ER (Experienced Researcher)'s strong background in mechanical/electrical engineering, microfluidics as well as in cell biology and Elvesys expertise in the Elvesys proprietary FASTGENE technology, the world fastest qPCR (qualitative Polymerase Chain Reaction) technique which has already been tested on Anthrax and Ebola simulating agents. We will integrate bacteria lysis, DNA extraction and PCR module into a single plastic chip. In the scope of the project, the prototype will be tested in simple situations. Once satisfactory results are obtained, it will be made ready for tests in real-case situations (urine sample) through existing collaborations between Elvesys and hospitals. The prototype will be expected to provide a reliable diagnosis from the sample input to fluorescence readout in less than 30 minutes. This technology can be extended to other disease diagnostics as well thus contributing to solving the current EU needs for fast point-of-care diagnostic technologies.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-SE - Society and Enterprise panel"], "Coordinated_in": ["France"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-09-01"], "Project_ID": ["750999"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE QUEEN'S UNIVERSITY OF BELFAST"], "EU_Contribution": ["EUR 255 349,80"], "Project_Title": ["Women\u2019s Plague Writing in Early Modern England"], "Total_Cost": ["EUR 255 349,80"], "Country": ["United Kingdom"], "Project_ACR": ["Womenswriting"], "Technology_Description": "In a time when high-profile outbreaks such as zika and ebola frequently make news headlines, the proposed research project, \u2018Women\u2019s Plague Writing in Early Modern England\u2019, provides an opportunity to interrogate how we interpret medical writing, who talks about medical problems and how gender becomes entangled in outbreaks by looking to the past. \u2018Women\u2019s Plague Writing in Early Modern England\u2019 will undertake a survey and analysis of women\u2019s plague writing in England from 1550 to 1700. A three-year Global Fellowship project with a two-year outgoing phase at the University of Toronto (UofT) and incoming phase at Queen\u2019s University Belfast (QUB), the research action takes an interdisciplinary approach to women\u2019s plague writing across the early modern period in England. The research programme explores the medical humanities through the lens of literature in its historical context. This project will change the canon of plague writing, which has hitherto focused on male-authored texts. Moving from the single outbreak focus seen in my first monograph, The Literary Culture of Plague in Early Modern England (forthcoming with Palgrave Macmillan), the outcome of the project makes the significant leap to studying a period of plague writing, a bigger-scale picture, with a broad chronology that captures major plague outbreaks in 1592, 1603, 1625, 1630, 1636 and 1665. The project encapsulates a full-period picture of women\u2019s interactions with plague and medicine and the corresponding gendering of plague writing. It will examine how women discuss the disease and how this differs from male-authored texts. It will ask how the medium chosen for publishing a text, print or manuscript, impacted how women discussed the disease. It will investigate how women\u2019s understanding of plague was gendered and, more broadly, how the textual construction of pestilence was gendered in early modern England.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["750969"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAT DE GIRONA"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Force/position control system to enable compliant manipulation from a floating I-AUV"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["IAUVcontrol"], "Technology_Description": "The aim of this project is the design and implementation of a control system for an intervention autonomous underwater vehicle (I-AUV), composed of an AUV equipped with a multi-degree-of-freedom (multi-DOF) manipulator, to enable it to perform fully autonomous compliant underwater manipulation. During this fellowship the experienced researcher will implement algorithms based on dynamic control/force control and perform extensive experimental trials with the real system, to present results beyond the state of the art. ", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["750063"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ABERYSTWYTH UNIVERSITY"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Reflexivity as capacity in EU\u2019s border security: a contribution to theory and practice through the case of Polish Border Guard training"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["RefBORDER"], "Technology_Description": "Lived experience of border guards receives surprisingly little attention given the current challenges of European border security and its humanitarian aspects. The proposal sets out a plan to redress this hiatus through conducting an important policy-relevant research project that encourages reflexivity as capacity in border guard training. As a follow-up from my previous research in European security and preliminary results from studying assistance to border reform, it aims to both aid the EU\u2019s efforts to establish a more efficient European Border and Coast Guard and foster greater humanitarian and democratic sensibilities in European border policy. In contrast to existing approaches which neglect reflective practice of actors on the ground, the project explores new empirical evidence, hones new theoretical avenues and develops participative dissemination techniques to nurture reflexivity in cooperation between scholars and practitioners. In order to do so, it studies the lived experience of Polish Border Guard (PBG) officers involved in the transformation of their service in the aftermath of EU enlargement which occurred at the intersection of receiving training from Western European border guards and providing training assistance to the Ukrainian Border Guard service. This unique situation of dual interaction triggers reflection and creates conditions for knowledge production that the project taps into. The core of the project consists in fieldwork with participants to study, make use of for participative design and inspire interpretations of shifting training methods towards installing greater reflexivity. The latter is planned as an innovative dissemination technique developed through the researcher\u2019s training in action research and reflective teaching practice at Aberystwyth University and tested in secondment with a local border guard facility to contribute to a more context-informed EU border security policy.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["749314"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE D'AIX MARSEILLE"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Groundwater effects on coastal ecosystems"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["GRECO"], "Technology_Description": "Coastal lagoons host some of the most dynamic, diverse and productive ecosystems on Earth, which are subject to significant pressure from human activities. Hydrological land-ocean connectivity is a universally accepted important driver of coastal ecosystems, but the ecological effects of groundwater and associated solute fluxes to coastal systems remain poorly understood for most of the world\u2019s shores. The overall goal of GRECO is to evaluate the role that groundwater fluxes play in the functioning and vulnerability of coastal lagoon ecosystems, by studying its effects on primary producers. This project encompasses a suite of innovative and interdisciplinary investigations aimed at (a) documenting the spatio-temporal distribution of groundwater-derived freshwater and nutrient inputs to lagoons and the exposure of benthic communities to groundwater-borne nutrients; and (b) evaluating the groundwater-derived effects on lagoon primary productivity by identifying the nutrient sources for primary production and the role of groundwater in lagoon ecological functioning. To these aims, two economically and ecologically important French lagoons with contrasting hydroecological conditions will be investigated by using new methods for coastal groundwater studies: 3D hydrodynamic numerical modeling and nutrient stable isotope analysis in primary producers. The novel understanding of groundwater-ecological interactions derived from this project will significantly advance the state-of-the art of groundwater studies in the coastal zone by providing direct evidences of ecological effects of groundwater discharge and by adding new methods to study groundwater implications. The results of GRECO will allow closing a current gap in the fundamental understanding of coastal processes, improving our capacity to sustainably manage hydrological and ecological resources in the coastal zone.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["748896"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN"], "EU_Contribution": ["EUR 166 156,80"], "Project_Title": ["Government of Life and Death: The Rise of Coercive Power in European Late Prehistory"], "Total_Cost": ["EUR 166 156,80"], "Country": ["Austria"], "Project_ACR": ["CoPOWER"], "Technology_Description": "CoPOWER will adopt state-of-the-art archaeological and bioarchaeological approaches to investigate the transition to urban society and the rise of increasingly sophisticated social control mechanisms in Europe 1200-500 BC. The rich burial record of Austria and northeast Italy is used as a case study. Many research projects have investigated social complexity and urbanization in the study area by focusing on the elite groups that supposedly spearheaded these processes; by contrast, CoPOWER will explore the life-histories of the marginal individuals that are often the forgotten victims of history. In doing so, it will (a) contribute to develop an analytical framework for identifying and assessing potential bioarchaeological correlates of social change and disruption in the mortuary record of any given society and (b) promote marginality studies in archaeology. These aims will be achieved by building upon the ER's previous expertise in archaeological theory, in conjunction with the new skills in human osteology, isotope and DNA analysis she will acquire over the MSCA. Through high-quality training at OREA and the Natural History Museum in Vienna, the ER will not only learn about human skeletal biology and various analytical and laboratory procedures, but also how to interpret the data resulting from these methods within a broad, comparative anthropological framework for bioarchaeological problem-solving. Collaboration on OREA\u2019s ECR-funded project The Value of Mothers to Society will also provide crucial training in project management and added-value knowledge on the gender dimension of inequality in Europe\u2019s late prehistory. The contributions of CoPOWER to understand the processes leading to social change and marginality under socio-environmental stress are extremely timely in today\u2019s worldwide order; its results 'will therefore fulfil the Horizon 2020 Programme\u2019s aims to promote EU excellence through top research across Europe and through a knowledge-based society.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Austria"], "Activity": ["Research Organisations"], "From": ["2017-07-01"], "Project_ID": ["750596"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF BRIGHTON"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Targeting Glioblastoma using Combinatorial Therapeutic Nanovaccine"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["GLIOMA"], "Technology_Description": "The proposal aims at the synthesis, characterisation and application of a novel therapeutic nanovaccine (TNVax) that holds multiple modules for targeting glioblastoma multiforme (GBM). The proposed TNVax formulation includes a gold nanocage core encapsulating Temozolamide (TMZ), coated with an extremophilic bacterial polysaccharide, mauran functionalised with anti-PD-L1 antibody and anti-CD133 antibody. The us of NVax nanoparticles (NPs) offers a combinatorial approach in killing GBM cells both by immuno- and chemo- therapeutically. Site-specific delivery of the payload will stimulate the host immune system and channel the immune cells to the target site. Functionalisation of the anti-PD-L1 antibody on drug-encapsulated NPs would significantly alter the immune suppression caused by GBM cells on TNVax delivery. In addition to anti-PD-L1 antibody, the TNVax particles contain tumour specific monoclonal antibody that specifically recognizes CD133 antigen and facilitates strong binding. This approach would enhance the amount of antitumour activity offered by multiple means and thereby leaving a strong immune response against GBM based on antigen-antibody interactions. TNVax NPs will be synthesised and characterised using microscopic and spectroscopic techniques and then subjected to in vitro and in vivo evaluations. In vitro studies will be performed for drug release kinetics and cytotoxicity using immunofluorescence and FACS analysis. Induction of immune response by TNVax NPs will be evaluated using macrophage activation, induction of T-cell activity and cytokine production under in vitro conditions. The pharmacokinetic and pharmacodynamic studies will be carried out and histopathological examinations performed using appropriate murine models induced with GBM cell lines. The potential outcomes of the proposed studies will help patients who suffer from early and advanced GBM by eradicating the disease permanently and leaving good immunological memory.", "To": ["2019-10-01, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-02"], "Project_ID": ["749403"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE"], "EU_Contribution": ["EUR 187 419,60"], "Project_Title": ["The role of the glucocorticoid receptor in dopaminoceptive neurons in mitochondrial dysfunction and vulnerability to depression"], "Total_Cost": ["EUR 187 419,60"], "Country": ["Switzerland"], "Project_ACR": ["MitoDyaD"], "Technology_Description": "Depression is considered as a common mental illness worldwide affecting around 350 million people. Chronic stress is a major risk factor for its development. Interestingly, individuals can differ in the way of coping with chronic stress and are either prone (vulnerable) or resistant (resilient) to develop depression. High anxiety-trait is a vulnerability factor to develop stress-induced depression. Furthermore, it was also linked with mitochondrial dysfunction in the nucleus accumbens and in the establishment of social hierarchies in rodents. These observations suggest an important role of mitochondria in the vulnerability to develop stress-induced depression. The glucocorticoid receptor that is activated upon stress was recently shown to regulate mitochondrial function and gene transcription. Our own data show that expression of the glucocorticoid receptor is altered in animals with high anxiety-trait correlating with the expression of several mitochondrial genes. Thus, our central hypothesis is that vulnerability to develop depression is caused by a glucocorticoid receptor-mediated dysfunction of mitochondria in the nucleus accumbens. This project will address this idea in the mouse model showing considerable individual differences in stress-induced psychopathology-like behavior. We will first examine the role of the glucocorticoid receptor in vulnerability to stress-induced depression by performing comprehensive behavioral studies. We will then evaluate the impact of the glucocorticoid receptor on mitochondrial function and structure. Lastly, we will apply a pharmacological approach aiming to mitigate stress-induced depression caused by physiological changes given by the glucocorticoid receptor. This will lead to the understanding of the contribution of the glucocorticoid receptor in the nucleus accumbens to define vulnerability and resilience to develop stress-induced depression, and might lead to novel therapeutics for counteracting stress-induced depression.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["748051"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF LEEDS"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Pregnancy and Reproduction Organ-on-a-chip Models"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["PROM"], "Technology_Description": "PreTerm Birth (PTB) occurs before 37 weeks of gestation. Of 60,000 babies born prematurely every year in UK, ~1,400 die. Premature babies show increased risks of long term neurodevelopmental deficits and chronic diseases.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["748903"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CHALMERS TEKNISKA HOEGSKOLA AB"], "EU_Contribution": ["EUR 178 993,80"], "Project_Title": ["Modulated Composite Structures: A 3D Bulk Approach to Incoherent Hetero-Structure Interface Engineering in Oxides for Future Low Temperature Energy Applications"], "Total_Cost": ["EUR 178 993,80"], "Country": ["Sweden"], "Project_ACR": ["MODCOMS"], "Technology_Description": "Interfaces between oxides can provide entirely new ways to realize novel properties. The goal of this research project is to further clarify the fundamental relationships between composition, crystal structure and ionic transport properties in a novel system based on the hexagonal YMnO3 type structure. This system shows a remarkably large reversible - oxygen storage capacity (LR-OSC) at very low temperatures 150-400C, and the experienced researcher(ER) hypothesizes that this transition may strongly depend on the energy related to the hetero-structure interface (HSI) formation that is naturally formed in modulated composite structures (MODCOMS); in this case between an YMnO3 and Y2Mn2O7 based structure in 3D (i.e., throughout the bulk material). ", "To": ["2020-02-29, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["748574"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSIDAD DE GRANADA"], "EU_Contribution": ["EUR 239 191,20"], "Project_Title": ["Homogeneous and heterogeneous enantioselective Single Electron Transfer (SET) catalysis in cross-coupling reactions"], "Total_Cost": ["EUR 239 191,20"], "Country": ["Spain"], "Project_ACR": ["EnanSET"], "Technology_Description": "Chirality of organic molecules plays a paramount role in our society as a consequence of the direct relation between the absolute molecular configuration and many properties and applications of molecular compounds and materials. The demand of enantiomerically pure compounds has increased considerably driven by the request of the pharmaceutical industry, as well as applications such as flavours, fragrances, and materials. In this context, the development of new methodologies to obtain enantiomerically pure compounds has become a challenge for the scientific community. ", "To": ["2021-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["749359"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CARL VON OSSIETZKY UNIVERSITAET OLDENBURG"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Test, Predict, and Improve Musical Scene Perception of Hearing-Impaired Listeners"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["TIMPANI"], "Technology_Description": "In both speech and music perception, the auditory system decomposes sounds that overlap in time and frequency into distinct perceptual events and streams, which is referred to as auditory scene analysis (ASA). Hearing-impaired listeners suffer from severely compromised ASA, as illustrated by their immense difficulties to understand speech in noisy environments. Although the central role of ASA in shaping the experience of music is widely acknowledged\u2014perceptually organizing sounds from multiple instruments or voices into melody and accompaniment, for instance\u2014the role of hearing loss in musical scene perception remains largely unexplored. At the same time, hearing aids are typically designed for speech perception, not for music perception. Adopting a transdisciplinary approach that employs methods from music perception, auditory modelling, and signal processing, this Marie Sk\u0142odowska-Curie Action aims to Test, Predict, and Improve Musical Scene Perception of Hearing-Impaired Listeners (TIMPANI). Firstly, a series of music perception tasks will be designed to assess the effects of hearing loss on musical scene perception abilities. Secondly, an auditory model will be developed in order to predict normal and hearing-impaired listeners\u2019 performance in ASA tasks. Finally, algorithms for scene-aware music mixing will be developed for improved music perception of hearing aid users. This research is timely and addresses the H2020 challenges to improve demographic change and wellbeing in European societies: The rise of hearing loss calls for scientific and technological breakthroughs in order to include hearing-impaired individuals in the cultural resource of music listening and making.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["747124"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Generating yeast biodiversity by mitochondrial introgression for wine innovation"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["Mitogression"], "Technology_Description": "Wine global demand is decreasing due to a shift in consumer preferences and cultural changes. The EU is a GLOBAL LEADER in WINE production, whose wine companies wants to decrease ethanol content, while improving organoleptic properties to deal with these new demands. YEASTS, mainly Saccharomyces cerevisiae, play a KEY ROLE during wine fermentation, when alcohol and the main flavors are produced. Application of new yeasts, produced by genetic engineering, is limited due to the non-acceptance of Genetically Modified Organisms (GMOs). We PROPOSE to apply non-GMO methodologies, to obtain IMPROVED YEASTS by the generation of yeast strains (cybrids), with mitochondrial genomes (mitogression) from non-cerevisiae species, or hybrids, increasing yeast DIVERSITY, to select strains whose fermentation products match wine company expectations. We will ANSWER some BASIC research QUESTIONS: how is genotype molded by the presence of a foreign mitochondrial genome? Are these changes common between independent experiments and wild isolates? And, are evolved strains starting to show evidence of speciation from their ancestors? The results of this project will IMPACT the WINE INDUSTRY by generating new potential commercial strains, and future collaborations. The knowledge gained through this proposal will demonstrate to the scientific community the use of novel methodologies as well as expose the general public to the importance of biodiversity for industrial processes and how the transfer of genetic material and experimental evolution can produce beneficial traits for our societies. The researcher (evolutionary biology and bioinformatics background), supervisor (microbiology, systems biology, and synthetic biology background), and host institution (facilities, knowledge, experience, and supporting elements) will form a perfect entity for the development of MITOGRESSION proposal, and to CONSOLIDATE the scientific career of the researcher for his future INDEPENDENT position.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["747775"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["EIDGENOESSISCHES DEPARTEMENT DES INNERN"], "EU_Contribution": ["EUR 187 419,60"], "Project_Title": ["Unravelling species barriers of coronaviruses"], "Total_Cost": ["EUR 187 419,60"], "Country": ["Switzerland"], "Project_ACR": ["COV RESTRIC"], "Technology_Description": "\"Human coronaviruses (CoVs) are distributed worldwide and cause a significant percentage of all common colds. Most of these viruses presumably emerged through zoonotic transmission, have adapted to the human host, and are now known to cause mild upper respiratory tract infections. However, the more recent zoonotic transmission of the highly pathogenic Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) have demonstrated the potential of coronaviruses to also cause highly severe human diseases and are associated with a high mortality. The precise mechanisms that allow coronaviruses to jump across species barriers are only poorly understood. \"COV RESTRIC\" aims to unravel species barriers of coronavirus infections and to uncover basic host cell mechanisms preventing a transmission across different species. We hypothesize that conserved restriction factors exist between different species which limit viral replication and which need to be overcome via viral evasion and adaptation strategies in order to establish a zoonotic infection. These may include the lack or genetic incompatibility of essential viral replication co-factors as well as the presence of antiviral restriction mechanisms. We will use two complementary genetic screening approaches to identify unknown coronavirus restriction factors. Once we have identified possible candidates, we will analyze them for their cross-conservation employing coronaviruses from different species, such as human, bat and camel virus isolates, as well as the respective primary cell culture material originating from the authentic host. This approach will help to rigorously define species barriers to viral transmission which should promote future development of preventive and therapeutic strategies to combat emerging RNA virus infections in humans.\"", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-SE - Society and Enterprise panel"], "Coordinated_in": ["Switzerland"], "Activity": ["Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2017-05-01"], "Project_ID": ["748627"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Enzyme-Degradable Polyion-Complex (PIC) Particles for the Treatment and Detection of Pseudomonas aeruginosa"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["AntibioPICs"], "Technology_Description": "Here, we will develop new enzyme-degradable polymers for the preparation of polyion complex (PIC) particles based of antimicrobial molecules with low charge densities. The main goals are:", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["747801"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAET REGENSBURG"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Baryons in extreme QCD matter"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["XQCDBaryons"], "Technology_Description": "Quantum Chromodynamics (QCD) undergoes a crossover from the hadronic phase at low temperatures T to a quark-gluon plasma (QGP) phase at high T. This crossover and properties of the QGP phase are important for understanding the evolution of the early universe and are being studied by major Heavy Ion Collision (HIC) experiments at RHIC and LHC. The transition temperature and many QGP properties have been determined by Lattice QCD simulations. However, connecting these to experimental remnants of QGP fireballs produced at HICs is not straightforward. Thermal effects will modify the properties of the excitations (mesons and baryons) within the medium. We propose to investigate these in-medium changes using lattice QCD methods, shedding light onto the dynamics of HIC fireballs.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["744659"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF LEEDS"], "EU_Contribution": ["EUR 251 857,80"], "Project_Title": ["Superconducting Spintronics for Highly Energery Efficient Cryogenic Memory Applications"], "Total_Cost": ["EUR 251 857,80"], "Country": ["United Kingdom"], "Project_ACR": ["SUPERSPIN"], "Technology_Description": "The dissipation of heat in traditional silicon (CMOS) based electronics is a major source of inefficiency and environmental impact. Superconductors are, by nature, dissipationless. Computing via logic circuits based on Josephson junctions is also faster, but the largest remaining problem is the lagging development of low-temperature memory. To achieve the promised efficiency increases of these computers requires a new type of low-temperature memory architecture.", "To": ["2020-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["743791"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAT DE LES ILLES BALEARS"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Simulating REalistic HIgh-resolution PREcipitation in the tropics"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["REHIPRE"], "Technology_Description": "Changes in rainfall characteristics over the Maritime Continent affect a rapidly increasing population of 275 million people through effects on agriculture, forest fires, floods and vector-borne diseases. However, current atmospheric models fail to represent most features of precipitation in the region, such as its distinctive strong diurnal cycle. Therefore, our knowledge of the physical processes initiating and propagating convective systems that generate precipitation in the Maritime Continent is very limited. In addition, the Maritime Continent is at a centre of interactions across scales, hence global model errors in this region propagate through the entire earth system and affect model estimates in remote regions too. This project is aimed at exploring our ability to simulate realistic precipitation by incorporating explicit convection and fine-scale ocean-atmosphere interactions in regional models. We will quantify the interplay between sea breeze circulation, ocean-atmosphere processes and convective systems to produce precipitation in the Maritime Continent and how it could change in the future. As such, this project will also advance our understanding of sea breeze and convective processes that are of major importance to a breadth of locations globally.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["743547"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KUNGLIGA TEKNISKA HOEGSKOLAN"], "EU_Contribution": ["EUR 173 857,20"], "Project_Title": ["Theoretical prediction of spectral biomarkers for Alzheimer's disease enabled by highly efficient and adaptable mutli-level response methods"], "Total_Cost": ["EUR 173 857,20"], "Country": ["Sweden"], "Project_ACR": ["FreezeAlz"], "Technology_Description": "Luminescent conjugated oligothiophenes are highly promising candidates for biomarkers for amyloid misfolds and thereby for early-stage detection of neurodegenerative diseases such as Alzheimer\u2019s and Parkinson's disease. The elucidation of the microscopic mechanism and design principles behind these biomarkers requires theoretical assistance. Finding suitable theoretical models that allow sufficiently accurate spectra calculations for such large, dynamic, and complex biomolecular systems is a highly challenging task: In practice, it is currently neither possible to include all possible factors, nor to rigorously test their importance for the actual simulation. There is, hence, a great need for efficient and adaptive theoretical models capable of incorporating the essential factors in spectra calculation of biomolecular systems sufficiently accurately.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["745906"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KOC UNIVERSITY"], "EU_Contribution": ["EUR 152 988"], "Project_Title": ["Critical Slope Gross-Zagier formula and Perrin-Riou's Conjecture"], "Total_Cost": ["EUR 152 988"], "Country": ["Turkey"], "Project_ACR": ["CriticalGZ"], "Technology_Description": "The main objective of this project is to prove a p-adic Gross-Zagier formula for the critical slope p-adic L-functions attached to p-ordinary modular forms. As we will explain in the main body of this proposal, such a formula will lead, among other things, to a full proof of a conjecture of Perrin-Riou (that gives a precise comparison between p-adic Beilinson-Kato elements and Heegner points). ", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Turkey"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["745691"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAT WIEN"], "EU_Contribution": ["EUR 166 156,80"], "Project_Title": ["Federal state against cities: Immigrant incorporation in the context of new immigrant reception"], "Total_Cost": ["EUR 166 156,80"], "Country": ["Austria"], "Project_ACR": ["FEDCIT"], "Technology_Description": "The unprecedented number of newcomers in the past year provides an immense challenge to federal state and local authorities, who have to co-ordinate the provision of policies and funds for incorporating immigrants into society. This comparative study seeks to understand the role of federal states for the incorporation of immigrants in the context of the recent influx of asylum seekers in Germany and Austria in 2015.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["740447"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE DE GENEVE"], "EU_Contribution": ["EUR 187 419,60"], "Project_Title": ["Deep brain targets for neurostimulation in affective disorders"], "Total_Cost": ["EUR 187 419,60"], "Country": ["Switzerland"], "Project_ACR": ["Debrasa"], "Technology_Description": "Objective: The overarching goal of proposed project is to provide necessary knowledge about neurobiology of Major Depression Disorder (MDD), which would lead to higher efficacy in treatment of this affective disorder. The research objectives of the action are 1) identification of electrophysiological biomarkers of functional brain abnormities in treatment resistant depression (TRD) and 2) suggestion of novel targets for neurostimulation in patients with TRD.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["739939"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI DI TRIESTE", "SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI DI TRIESTE"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Neuromicronica: Modular behavioural neuroscience"], "Total_Cost": ["EUR 150 000"], "Country": ["Italy", "Italy"], "Project_ACR": ["NEUROMICRONICA"], "Technology_Description": "Neurological disorders, particularly dementia, constitute arguably the greatest socioeconomic challenge to the aging European continent. There is growing realization that rodents can serve as models not just for basic neurobiological processes (e.g. synaptic transmission) but also for remarkably complex, primate-like and even human-like cognitive operations such as perception, memory, economics, social interaction, and decision making. Better rodent models for cognition are necessary to test theories on the molecular basis of neurological disorders and to test therapies: only through rodent behavioral neuroscience can the circuits that give rise to cognitive operations be examined and dissected, probed and manipulated. The aim of ERC Advanced Project \u2018CONCEPT\u2019 is to understand the neuronal bases of perception, memory and decision making. To achieve this aim, we have developed innovative instrumentation incorporating the following elements: (i) awake rodent interacting with its environment, (ii) precisely controlled sensory stimuli, (iii) imaging of animal\u2019s action, (iv) electrophysiology with moveable microelectrode arrays, (v) optogenetics, (vi) integration and management of all incoming and outgoing signals. Here, we present our plan for bringing these instruments to a stage where they can constitute the initial product line for a spin-off named NeuroMicronica. The community\u2019s interest in NeuroMicronica is already testified by the commercialization of the electrode drive in agreement with a prestigious USA company, by NeuroMicronica\u2019s selection in a technology startup competition, and by the enthusiastic and constructive feedback from collaborators now employing beta versions. The expected outcome of NeuroMicronica will be to make this lab\u2019s longstanding experience in instrumentation available to the community, allowing investigators to better exploit rodent behavioral neuroscience as a model for normal and pathological human cognition.", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["737609"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 1 981 721"], "Project_Title": ["Hybrid Indium Phosphide on Silicon nanophotonics for ultimate laser diodes, flip-flops and memories"], "Total_Cost": ["EUR 1 981 721"], "Country": ["France", "France"], "Project_ACR": ["HYPNOTIC"], "Technology_Description": "The HYPNOTIC project aims at achieving a breakthrough in Silicon laser science and technology by taking forward the III-V semiconductors on Silicon hybrid technology into the nanophotonic world to make the dream of the convergence of microelectronics and photonics on a chip come true. This project intends to take up the challenge of bringing to reality electrically powered photonic crystal nanolasers as reference sources for dense integration and logical processing in a Silicon-based optical platform by accomplishing: (i) power efficiency with extremely low activation energies of few fJ, (ii) high bandwidth beyond 40Gbits/s, (iii) compactness with footprints less than 100\u00b5m\u00b2 for high integration density of 103-104 of devices per mm2.", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-04-01"], "Project_ID": ["726420"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["VIB", "VIB"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["A comparative clinical study of a stool-based versus a blood-based screening test for earlydetection of CRC"], "Total_Cost": ["EUR 150 000"], "Country": ["Belgium", "Belgium"], "Project_ACR": ["Monomark"], "Technology_Description": "Colorectal cancer (CRC) is the third most common cancer worldwide and the second leading cause of cancer deaths in Europe and USA. Its incidence and difficult early-diagnosis make CRC a primary focus in the oncology community. Although colonoscopy is currently the most reliable clinical tool for precise detection of CRC, the invasive nature and the incurred cost have hampered the wide application of this procedure. On the other hand, the fecal occult blood test (FOBT) and the fecal immunoistochemical test (FIT) are non-invasive screening tests that can be used prior to colonoscopy. However, they both lack the sensitivity or specificity required for an effective screening tool and they require meticulous dietary restriction, overall not reaching the full compliance of the general population. Thus, there is a pressing need to identify specific non-invasive biomarkers for early diagnosis of CRC. Within the frame of the ERC starting grant OxyMO, we investigated the diagnostic potential of blood derived circulating monocytes for colorectal cancer (CRC). Our transcriptome characterization revealed a CRC-specific gene signature that was further developed as the \u2018Monomark\u2018 diagnostic test (patent WO2013/110817), which showed a strong diagnostic power for CRC detection. This signature was triggered by signals specifically released by CRC cells regardless of their stromal niche (primary tumor vs. metastatic site) or oxygen tension. In this prospective study, we will compare the strength of the Monomark signature towards the FIT test in patients with a positive stool test. Therefore, in parallel to the routine FIT screening, blood samples will be harvested and the monocyte genetic profile will be determined. This fundamental study, will disclose the diagnostic power of our biomarker panel head to head with the well-established FIT diagnostic test, a core prerequisite for the commercialization of the Monomark test as an alternative and more reliable CRC screening tool.", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Belgium"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-04-01"], "Project_ID": ["737596"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE"], "EU_Contribution": ["EUR 1 998 971"], "Project_Title": ["Uranium isotope fractionation: a novel biosignature to identify microbial metabolism on early Earth"], "Total_Cost": ["EUR 1 998 971"], "Country": ["Switzerland", "Switzerland"], "Project_ACR": ["UNEARTH"], "Technology_Description": "Prokaryotes (archaea and bacteria) are the most abundant form of life both at present and throughout paleohistory and exhibit exquisite metabolic diversity, unmatched by eukaryotes. On early Earth, the absence of atmospheric oxygen led to the emergence of anaerobic microbial metabolisms such as methanogenesis, sulfate reduction, iron reduction, and denitrification. Non-isotope and isotope tools used to study ancient microbial life have provided evidence for each of these types of metabolisms in the rock record. However, there remains much uncertainty and debate regarding this evidence, primarily because of confounding effects of abiotic processes, and ambiguity in interpretation of isotopic signatures. ", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["725675"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITAET HAMBURG", "UNIVERSITAET HAMBURG"], "EU_Contribution": ["EUR 1 923 190"], "Project_Title": ["Slow motion: Transformations of musical time in perception and performance"], "Total_Cost": ["EUR 1 923 190"], "Country": ["Germany", "Germany"], "Project_ACR": ["SloMo"], "Technology_Description": "Slow motion is widely employed in popular media such as emotional movie scenes or in the broad-casting of momentous bodily and physical actions. Slow motion functions as a counterpoint to the perceived acceleration of life, and non-profit organisations and meditation practices promote its virtues. Slow motion is used as a beneficial rehearsal strategy in music, dance, and other movement-based arts and sports. This research proposal shifts existing boundaries by hypothesizing that the time-stretching mechanism of slow motion is a) associated with high emotional significance, b) beneficial for interpersonal coordination, c) relevant in cross-modal approaches with augmented feedback such as the sonification of human movements, d) reduces cognitive working memory load in learning. It is assumed that music as a temporal-motional art is central for the study of these processes, since music consists of structured time at different hierarchical levels and deeply \u201cmoves\u201d people. The musical surface structure (on a note-to-note level) allows synchronisations at higher tempi compared to deeper structural levels (such as strong beats in a measure or phrases). Music may thus transform perceptions of motion and time. The proposed project contains three main phases, first addressing the perception of slow motion in music and dance in relation to the attentional, emotional and aesthetic effects on the audience. In the second phase, performance qualities are studied, addressing cognitive load, imagery, and interpersonal coordination at slow tempi. High-speed cameras, a 3D motion capture system and physiological measures are used to analyse the psychological and bodily processes involved. The final phase aims at the creation of three applications, including a learning app for portable devices, a film with super slow motion sequences based on the studies, and sonifications of Tai Chi movements. These applications present the aesthetic dimensions of slow motion to a wider audience.", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["725319"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON", "UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 1 358 925"], "Project_Title": ["Birational Geometry, B-branes and Artin Stacks"], "Total_Cost": ["EUR 1 358 925"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["BG-BB-AS"], "Technology_Description": "Derived categories of coherent sheaves on a variety are a fundamental tool in algebraic geometry. They also arise in String Theory, as the category of B-branes in a quantum field theory whose target space is the variety. This connection to physics has been extraordinarily fruitful, providing deep insights and conjectures.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["725010"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["HERIOT-WATT UNIVERSITY", "HERIOT-WATT UNIVERSITY"], "EU_Contribution": ["EUR 1 999 135"], "Project_Title": ["Two-dimensional quantum photonics"], "Total_Cost": ["EUR 1 999 135"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["2DQP"], "Technology_Description": "Quantum optics, the study of how discrete packets of light (photons) and matter interact, has led to the development of remarkable new technologies which exploit the bizarre properties of quantum mechanics. These quantum technologies are primed to revolutionize the fields of communication, information processing, and metrology in the coming years. Similar to contemporary technologies, the future quantum machinery will likely consist of a semiconductor platform to create and process the quantum information. However, to date the demanding requirements on a quantum photonic platform have yet to be satisfied with conventional bulk (three-dimensional) semiconductors.", "To": ["2022-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["725920"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITAET PADERBORN", "UNIVERSITAET PADERBORN"], "EU_Contribution": ["EUR 1 963 750"], "Project_Title": ["Quantum Particles on Programmable Complex Reconfigurable Networks"], "Total_Cost": ["EUR 1 963 750"], "Country": ["Germany", "Germany"], "Project_ACR": ["QuPoPCoRN"], "Technology_Description": "Understanding the complex interactions and dynamics of multiple quantum particles within large networks is an extremely challenging task, but doing so reveals the underlying structure of an enormously diverse range of phenomena. Therefore, a reliable platform to investigate complex quantum network dynamics, which incorporates the rich interplay between noise, coherence and nonclassical correlations, will be an extremely powerful tool. ", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["725366"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich"], "EU_Contribution": ["EUR 1 505 000"], "Project_Title": ["MULtiple PROperties Single Molecule Magnets"], "Total_Cost": ["EUR 1 505 000"], "Country": ["France", "France", "Switzerland"], "Project_ACR": ["MULTIPROSMM"], "Technology_Description": "The goal of the MULTIPROSMM project is to design systems able to present magnetic bistabilities under different stimuli (temperature, magnetic field or light) on an unprecedented large temperature range, i.e. very low temperature with Single Molecule Magnet (SMM) behaviour, intermediate temperature with Light Induced Excited State Trapping (LIESST) and high temperature with SpinCrossOver (SCO). On one hand, as a photography of the energy-splitting of the spectroscopic states, the lanthanide luminescence will be used as a key tool for the understanding of the magnetic properties of lanthanide ions. On the other hand, Circularly Polarized Luminescence (CPL) combines the sensitivity of the luminescence with crucial information on the chiral environment. A step by step synthetic strategy will be used to elaborate molecular systems in which the coexistence of i) SMM and SCO; ii) SMM and CPL and iii) SMM, SCO and CPL are operating. The enhancement of the magnetic properties is needed to step forward towards applications. To reach such optimizations, the quantum regime of the SMM and the internal magnetic field must be vanished playing with the hyperfine coupling and magnetic dilutions. Both isotopic enrichment and shaping (i.e. decoration of both mesoporous silica and nanoparticle surfaces) of the designed systems could allow high magnetic performance in multiple properties SMM. The final result could be a system suitable for very high density data storage on a wide temperature range (from cryogenic to room temperature).", "To": ["2022-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["725184"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["JOHANNES GUTENBERG-UNIVERSITAT MAINZ", "JOHANNES GUTENBERG-UNIVERSITAT MAINZ"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Novel structures in scattering amplitudes"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Germany", "Germany"], "Project_ACR": ["AMPLITUDES"], "Technology_Description": "This project focuses on developing quantum field theory methods and applying them to the phenomenology of elementary particles. At the Large Hadron Collider (LHC) our current best theoretical understanding of particle physics is being tested against experiment by measuring e.g. properties of the recently discovered Higgs boson. With run two of the LHC, currently underway, the experimental accuracy will further increase. Theoretical predictions matching the latter are urgently needed. Obtaining these requires extremely difficult calculations of scattering amplitudes and cross sections in quantum field theory, including calculations to correctly describe large contributions due to long-distance physics in the latter. Major obstacles in such computations are the large number of Feynman diagrams that are difficult to handle, even with the help of modern computers, and the computation of Feynman loop integrals. To address these issues, we will develop innovative methods that are inspired by new structures found in supersymmetric field theories. We will extend the scope of the differential equations method for computing Feynman integrals, and apply it to scattering processes that are needed for phenomenology, but too complicated to analyze using current methods. Our results will help measure fundamental parameters of Nature, such as, for example, couplings of the Higgs boson, with unprecedented precision. Moreover, by accurately predicting backgrounds from known physics, our results will also be invaluable for searches of new particles.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["725110"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITEIT UTRECHT", "UNIVERSITEIT UTRECHT"], "EU_Contribution": ["EUR 2 496 611"], "Project_Title": ["BiogENesis and Degradation of Endoplasmic Reticulum proteins"], "Total_Cost": ["EUR 2 496 611"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["BENDER"], "Technology_Description": "The Endoplasmic Reticulum (ER) membrane in all eukaryotic cells has an intricate protein network that facilitates protein biogene-sis and homeostasis. The molecular complexity and sophisticated regulation of this machinery favours study-ing it in its native microenvironment by novel approaches. Cryo-electron tomography (CET) allows 3D im-aging of membrane-associated complexes in their native surrounding. Computational analysis of many sub-tomograms depicting the same type of macromolecule, a technology I pioneered, provides subnanometer resolution insights into different conformations of native complexes. ", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["724425"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE", "INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE"], "EU_Contribution": ["EUR 2 091 338"], "Project_Title": ["Protection of cardiometabolic inflammation by modulation of myeloid glutamine homeostasis"], "Total_Cost": ["EUR 2 091 338"], "Country": ["France", "France"], "Project_ACR": ["PROGLUTASIS"], "Technology_Description": "The metabolic syndrome (MetS) represents one of the major public health challenges worldwide. It reflects a combination of medical disorders that, when occurring together, increase the risk of developing diabetes and cardiovascular disease. The prevalence in the USA is estimated at 30% of the population and the European community follows this trajectory. It is now recognized that the state of chronic low-grade inflammation may favor the onset and progression of the MetS. While the notion of metabolic flexibility in hematopoietic cells has recently emerged in several inflammatory diseases, the origin of this immunometabolic alteration in the MetS remains elusive. There is a growing appreciation that the apportioning of nutrients into different metabolic pathways can support or direct functional immune and hematopoietic changes. Glutamine is the most abundant amino acid in the plasma and an important energy source through glutaminolysis. Despite its potential proliferative and/or immunosuppressive function and the strong association between high glutamine-to-glutamate ratio with cardiometabolic traits, the underlying mechanisms are poorly understood. Thus, there is a considerable therapeutic interest in better understanding the mechanisms linking glutamine to cardiometabolic risks and in particular cardiometabolic inflammation. In PROGLUTASIS, we will investigate the metabolic and immune regulation of glutamine homeostasis in the metabolic syndrome. We will validate the contribution of glutaminolysis in cardiometabolic inflammation, including obesity, diabetes and atherosclerosis through its role on hematopoiesis and macrophage dynamics. Given the ubiquitous association between glutamine and chronic metabolic stress, we expect that identifying the underlying molecular mechanism will offer novel therapeutic perspective on how to intervene in this pathway. This will ultimately allow for tailored strategies aimed at dampening cardiometabolic inflammation in the MetS.", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-04-01"], "Project_ID": ["724838"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["POLITECNICO DI MILANO", "POLITECNICO DI MILANO"], "EU_Contribution": ["EUR 1 999 194"], "Project_Title": ["MIcrobiota-Gut-BraiN EngineeRed platform to eVAluate intestinal microflora impact on brain functionality"], "Total_Cost": ["EUR 1 999 194"], "Country": ["Italy", "Italy"], "Project_ACR": ["MINERVA"], "Technology_Description": "What is the relation between the intestinal microflora and the brain in the development of neurodegenerative disorders like Alzheimer's and Parkinson's disease? ", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["724734"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["ALBERT-LUDWIGS-UNIVERSITAET FREIBURG", "ALBERT-LUDWIGS-UNIVERSITAET FREIBURG"], "EU_Contribution": ["EUR 1 982 938"], "Project_Title": ["Towards the ultimate dark matter detector"], "Total_Cost": ["EUR 1 982 938"], "Country": ["Germany", "Germany"], "Project_ACR": ["ULTIMATE"], "Technology_Description": "Dark matter is a major component of the Universe, outnumbering ordinary baryonic matter by a factor 5. As it has not yet been observed, its detection and subsequent characterization is one of the most important goals in particle physics. ULTIMATE will be the first project world-wide that focuses entirely on cutting-edge research towards the ultimate detector. Using a low-background time projection chamber (TPC) filled with ~40t of liquid xenon (LXe), this instrument will search for Galactic dark matter in the form of Weakly Interacting Massive Particles (WIMPs). It will probe the entire experimentally accessible parameter space above masses of a few GeV/c\u00b2, which is eventually limited by irreducible neutrino backgrounds. If dark matter will be detected by the next-generation experiments, the ultimate detector will deliver a high statistics WIMP sample to study its properties.", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["724320"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET", "BROWN UNIVERSITY"], "EU_Contribution": ["EUR 260 227,80"], "Project_Title": ["Local Diversity and Long-Run Development"], "Total_Cost": ["EUR 260 227,80"], "Country": ["Denmark", "United States"], "Project_ACR": ["LODALORD"], "Technology_Description": "Social scientists have long studied the effects of population diversity on society. The research project proposed here breaks new ground in multiple dimensions by rigorously estimating the long-run effects of (i) local population diversity, (ii) individual diversity, and (iii) the interaction between these two concepts, on comparative socioeconomic performance across locations and lineages within a country.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["753615"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI PADOVA", "UNIVERSITA DEGLI STUDI DI PADOVA"], "EU_Contribution": ["EUR 1 498 232"], "Project_Title": ["Dissecting the crosstalk between metabolism and transcriptional regulation in pluripotent stem cells."], "Total_Cost": ["EUR 1 498 232"], "Country": ["Italy", "Italy"], "Project_ACR": ["MetEpiStem"], "Technology_Description": "Pluripotent Stem cells (PSCs) can give rise to all differentiated cells of the body and the germ line, which makes them conceptually fascinating and a valuable tool for regenerative medicine. Mouse PSCs are devoid of any developmental restriction partly thanks to their \u201copen\u201d chromatin, characterised by remarkably low levels of repressive epigenetic modifications. Metabolism is a key feature that can be adjusted to meet the cell\u2019s needs, and that has the potential to feedback on transcription and epigenetics. How metabolism is regulated in PSCs and whether this is important for their biology remains largely unknown.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["716910"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["CONSIGLIO NAZIONALE DELLE RICERCHE"], "EU_Contribution": ["EUR 244 269"], "Project_Title": ["On the route of multiculturalism(s). Marking and hybridizing identities in the late 17th and early 18th centuries Mediterranean port cities"], "Total_Cost": ["EUR 244 269"], "Country": ["Italy"], "Project_ACR": ["MedRoute"], "Technology_Description": "This project aims to analyze the phenomenon of multiculturalism in four Mediterranean port cities of the late seventeenth and the early eighteenth centuries. The research uses three identity markers (foodways, clothing, and language) to chart how differences in the political and physical environments affect the balance between marking and hybridizing identities in the port cities of Izmir, La Valletta, Livorno and Marseille. Although very different amongst themselves, these four cities, placed on a maritime trading route cutting the Mediterranean from east to west, share a highly developed cultural, ethnical, and religious pluralism. The comparative analysis adopted will shed light on the concept of multiculturalism(s) in the pre-modern Euro-Mediterranean space, explaining how members of the same group handled coexistence following different strategies. In analyzing identity as a dynamic process, the research enters into the historiographical debate on the One-Plural nature of the Mediterranean on two critical levels: the ways in which Mediterranean identities interact with one another and how they generate a multicultural zone. Through an interdisciplinary study, the project will shape the ineradicable ambiguous nature of multicultural zones in the Mediterranean. This goal will be undertaken through the analysis and verification of three main assumptions that form the basis of the research:", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["747030"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["Institute of Science and Technology Austria", "Institute of Science and Technology Austria"], "EU_Contribution": ["EUR 1 984 922"], "Project_Title": ["Cellular navigation along spatial gradients"], "Total_Cost": ["EUR 1 984 922"], "Country": ["Austria", "Austria"], "Project_ACR": ["GRADIENTSENSING"], "Technology_Description": "Gradients of extracellular signalling molecules are a central concept in biology: for example gradients of guidance-cues such as chemokines position migrating cells in development, malignancy and immunity. Because immune cells are permanently motile, their function most critically depends on spatiotemporal orchestration by a large family of chemokines. To specify direction, concentration differences of the chemokine need to be interpreted by the migrating cell. Most mechanistic knowledge about eukaryotic gradient sensing is inferred from the amoeba Dictyostelium discoideum migrating towards soluble gradients of cyclicAMP. The biology of chemokines is much more diverse, e.g. gradients can take different shapes and, importantly, they do not only emerge in the soluble but also in the immobilized phase. In this proposal we suggest to address the principles of leukocyte chemotaxis using convergent system wide, cell biological and intravital approaches. Employing a newly developed, genetically tractable primary leukocyte system, we will test the contribution of spatial and temporal signalling paradigms of gradient sensing. Quantitative microscopy will be used to image cellular responses to engineered immobilized and soluble chemokine gradients of defined shape as well as to optogenetically triggered signals. In a complementary approach we will screen for proteins responding to chemokine signalling and perform the first genome wide genome editing-based loss of function screen for directionally persistent chemotaxis and haptotaxis. Findings will be validated in vivo to guarantee physiological relevance. In a support project we will precision-engineer the genome of primary leukocytes suitable for assaying migration. A unique combination of cellular, genetic, engineering and quantitative microscopy tools will allow this new and holistic approach to a question which is not only fundamental for immunology but also for understanding development and cancer biology.", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["724373"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 212 194,80"], "Project_Title": ["The International Criminal Court and the Judicial Function: a Socio-Legal Study of Judicial Perceptions and Practices"], "Total_Cost": ["EUR 212 194,80"], "Country": ["Denmark"], "Project_ACR": ["INCRICO"], "Technology_Description": "INCRICO investigates the ways in which the International Criminal Court (ICC) perceives its judicial function and how this impacts its legal practices. The overall goal is to offer a realistic account of the international criminal judiciary with regard to judicial deliberations, reasoning and drafting judgments. To meet this objective, INCRICO aims to tackle the topic using a unique interdisciplinary approach, employing doctrinal legal analysis as well as contemporary sociology of law for explaining international criminal law and international criminal courts and their link to global society. The project\u2019s specific objectives are to: (1) gather, analyse and collate international legal data and sources relevant for determining the content, scope, nature and practice of the ICC\u2019s judicial function, as well as the relevant body of the ICC\u2019s case law/jurisprudence/applicable law, including dissenting and individual/separate opinions; (2) gather (through in-depth interviews with the ICC's judges) and analyse qualitative data on the judges\u2019 perceptions and understanding of their judicial function, in terms of what and how the judges really think, and what they are doing and why, so as to identify the judges\u2019 view and experience at the ICC and how this correlated to the case law of the Court; (3) integrate legal assessment of dissents/case law/jurisprudence of the ICC with the judges\u2019 accounts to map out and critically analyse the ICC\u2019s judicial function; (4) increase awareness and knowledge of the ICC\u2019s judicial function among relevant scientific and criminal justice management/policy making communities, and the general public. INCRICO is involving an excellent academic and interdisciplinary environment at iCourts where the researcher will spend the entire period. This is a unique proposal which targets growing concerns on legitimacy, effectiveness, independence and fairness of global criminal judiciary. Thus, it fits perfectly with the goals of the IF and Horizon 2020.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["746768"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITEIT UTRECHT", "UNIVERSITEIT UTRECHT"], "EU_Contribution": ["EUR 1 499 082"], "Project_Title": ["\u2018This country is ours\u2019: Collective psychological OWNERShip and ethnic attitudes"], "Total_Cost": ["EUR 1 499 082"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["OWNERS"], "Technology_Description": "Even in the absence of legal ownership, people tend to experience objects, places, and ideas as belonging to them (\u2018mine\u2019). This state of mind is called psychological ownership. Research has shown that experiences of ownership are very important for individuals, but can also lead to interpersonal conflicts. What we know almost nothing about is collective psychological ownership (CPO): a shared sense that something is \u2018ours\u2019. CPO might be especially relevant with regard to territories and in the context of intergroup relations. Statements like \u2018we were here first\u2019 or \u2018we built this country\u2019 are increasingly used by right-wing politicians in immigration countries to claim ownership on historical basis for the dominant ethnic group, and to exclude newcomers. There are also contexts where two established groups disagree about territorial ownership, such as Albanians and Serbs in Kosovo.", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["715842"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["UNIVERSITY OF YORK"], "EU_Contribution": ["EUR 269 857,80"], "Project_Title": ["Quantum Sensing for Biology"], "Total_Cost": ["EUR 269 857,80"], "Country": ["United Kingdom"], "Project_ACR": ["QSB"], "Technology_Description": "Modern physics has contributed to the development of powerful instruments and diagnostic tools for biology and medicine, with a direct impact on both our well-being and life expectancy. Today, it is timely to ask if the novel field of quantum information is ready to provide new methods for the life sciences. This proposal makes a step in this direction, introducing non-invasive quantum techniques for experimental biology, with potential applications to biomedical imaging. My goal is to show how quantum correlations (entanglement or discord) can be exploited to realize a fully non-invasive form of spectroscopy, which can be safely applied to fragile materials, such as photo-degradable biological samples (DNA/RNA) or in-vivo human tissues. These objectives are not met in today\u2019s biology labs, where UV-light photometry heavily damages DNA/RNA samples, or in public hospitals, where X-ray scans expose patients to significant radiation doses, with non-negligible risks of cancer. The basic rationale behind the use of quantum correlations relies on their superior capacity to detect small variations in the absorption properties of the materials, even when only a few photons are employed. By exploiting this remarkable feature, I will prove the possibility of non-invasive testing of biological samples. My central task will be the design of a practical model of a quantum-enhanced photometer which is fully based on continuous-variable systems. This design will involve the extension of quantum sensing and metrology to a more advanced double-box formulation where two channels, representing seeded and blank samples, are simultaneously probed. The realization of such a quantum-enhanced instrument would allow for real-time continuous measurements of organic molecules and nucleic acids without any photo-degradation.", "To": ["2020-07-06, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-07"], "Project_ID": ["745727"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["LUNDS UNIVERSITET"], "EU_Contribution": ["EUR 173 857,20"], "Project_Title": ["Supercritical carbon dioxide for delipidation of soft tissue - Suppressing transplant rejection."], "Total_Cost": ["EUR 173 857,20"], "Country": ["Sweden"], "Project_ACR": ["CriTiClean"], "Technology_Description": "The lack of donor organs and tissue constitutes a health and social problem. In 2014 about 119.873 organs were transplanted, that is less than the 10% of global needs. Critical patients do not survive the waiting time while transplanted people must receive lifelong immunosuppressive therapy with severe side effects. Also, there is a risk to lose the new organ to chronic rejection, which is linked to the presence of cellular components e.g. glycolipids and lipoproteins in the donor tissue. There is currently no process to remove lipids and lipid antigens from soft tissue prior transplantation.", "To": ["2019-05-21, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-22"], "Project_ID": ["746137"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN"], "EU_Contribution": ["EUR 187 866"], "Project_Title": ["Human Rights, Memorialization and Nationalism"], "Total_Cost": ["EUR 187 866"], "Country": ["Ireland"], "Project_ACR": ["HRMN"], "Technology_Description": "This research deals with the rise of memorialization standards and policy-oriented attempts to engage transitional societies to develop and adopt specific normative forms of remembrance. This project addresses one particular human rights assumption - that the standardization of memory enforced through memorialization policies is effective and necessary in promoting human rights values. Human rights advocates insist on memorialization as a crucial step in establishing moral responsibility for past atrocities understanding it as an insurance policy against the repetition of crimes. In nationalist ideologies, however, memory and memorialization is used for the sake of defining the \u201cself\u201d and the \u201cother\u201d through boundaries along ethnic lines. The project investigates the ways in which human rights advocates understand, promote and mandate supposedly universal memorialization standards, asking whether in so doing they weaken or instead often actually strengthen nationalism. Within the University College Dublin, School of Sociology, and under supervision of Prof Male\u0161evi\u0107, a world-known expert in nationalism, the goal of this project is to get 1) new theoretical framework for the critical interdisciplinary study of human rights` memorialization policy; 2) new empirical insights into whether in different national contexts (in the Balkans and the Middle East) the prescribed standards of memory are being promoted, and if so, by whom and to what ends; 3) to develop case and gender-sensitive and cost-effective policy recommendations for future implementation of the EU human rights` memorialization policies. Successful realization of the project will enable Dr David to get a tenure track position at Hebrew University, where she will further use the acquired knowledge to search for innovative solutions to strengthen human rights.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["745922"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET", "KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 1 999 750"], "Project_Title": ["New and Old Histones in Epigenetic Cell Memory"], "Total_Cost": ["EUR 1 999 750"], "Country": ["Denmark", "Denmark"], "Project_ACR": ["HISTONEMEMORY"], "Technology_Description": "Cell type specific organization of DNA into chromatin is an important determinant of gene expression and cell identity. During cell division, epigenetic information in chromatin must be transmitted to daughter cells in order to maintain cell identity or commit to a developmental program. However, it remains unknown how epigenetic states are inherited during cell division. Elucidating molecular mechanisms underlying epigenetic cell memory thus represents a major challenge in biology critical to understand development and disease.", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["724436"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["WEIZMANN INSTITUTE OF SCIENCE", "WEIZMANN INSTITUTE OF SCIENCE"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["NovEl Strategies for treatIng tendon-to-bone injurieS - kiNESIS"], "Total_Cost": ["EUR 150 000"], "Country": ["Israel", "Israel"], "Project_ACR": ["kiNESIS"], "Technology_Description": "Body movement requires efficient transfer of force from contracting muscles to bone. Damage to the tendinous insertions is the 8th leading cause of disease burden and is the largest single cause of work loss in Europe. Historically, approaches for improving healing in these attachment units have focused on modifying repair techniques and rehabilitation protocols. These methods are proven to be very ineffective, since failure rates of as high as 94% are often reported. ", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2016 - ERC-Proof of Concept-2016"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["737473"], "Call_for_Proposal": ["ERC-2016-PoC"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Understanding the physical biology of adult blood stem cells"], "Total_Cost": ["EUR 1 500 000"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["PHYSBIOHSC"], "Technology_Description": "The discovery of functional heterogeneity in normal and malignant stem cells has shifted our understanding of how single cells are subverted to drive cancer. To design therapies for diseases of stem cell origin and to better provide cell populations for clinical applications, it is critical to understand this diversity at the single cell level. This proposal focuses on understanding the complex biology of normal and malignant stem cells and the impact of individual mutations on clonal evolution by studying the physical and quantitative aspects of single blood stem cells. ", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["715371"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["KAROLINSKA INSTITUTET"], "EU_Contribution": ["EUR 173 857,20"], "Project_Title": ["Characterizing Microbe-specific Immune Responses in the pathogenesis of Autoimmunity"], "Total_Cost": ["EUR 173 857,20"], "Country": ["Sweden"], "Project_ACR": ["MIRA"], "Technology_Description": "Dysregulation in the balance of CD4+ T helper cell populations can severely alter susceptibility to a number of chronic inflammatory diseases, including inflammatory bowel disease (IBD). The incidence of IBD is dramatically increasing in Europe and worldwide and its therapy represents an important unmet medical need, since a significant proportion of patients fail to respond to currently available immunotherapies. Therefore, a better characterization of the immunological events underlying each form of IBD is of foremost importance. Increasing evidence points to the pivotal role of a dysregulated mucosal immune response to the intestinal microbiota in the pathogenesis of IBD. However, little is known about the mechanisms contributing to the generation of commensal-specific adaptive immune responses, and whether their differential localization can shape severity and anatomical extent of the disease. Indeed, the intestines comprise anatomically distinct regions that are exposed to different luminal antigens and this diversity eventually determines a regionalization of intestinal immune functions and microbiota-specific T cell responses. The aim of this proposal is to deeply characterize microbiota-specific T cell responses generated under different inflammatory conditions, in terms of differentiation, plasticity, heterogeneity, function and homing potential. To this aim, the proposed work will combine the use of CBir1 TCR transgenic mice, whose T cells recognize a microbial antigen that is immunodominant in IBD patients, and cutting-edge techniques such as single-cell RNA sequencing.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["746628"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["QUEEN MARY UNIVERSITY OF LONDON"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Developing a Bayesian technique to evaluate the validity of economic models: two applications to the Euro Area"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["BMC-SVAR"], "Technology_Description": "The 2007 financial crisis and the 2009 European sovereign debt crisis highlighted how difficult it is to build models that capture the dynamics of the economic system. The project develops a model evaluation technique that allows a researcher to assess how much the economic models of interest to a researcher are supported by the data. The innovative technique set out in the project is developed in order to assist policy-makers address a wide variety of research questions, and to help them achieve their goals \u2013 for example, predicting the impact of interest rate changes on a country\u2019s economy. Two applications to monetary policy by the European Central Bank are developed. The first application studies whether the data support a class of economic models used to assess monetary policy. The second application studies how successful monetary policy has been in counteracting deflationary pressures in the Euro Area. ", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["744010"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FIRAMIS UG"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Backreaction of Financial Networks: Risk Estimation and Asset-Management"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["FinNet"], "Technology_Description": "The financial market is a relevant part of our economy. Its crisis spread all over the countries and affect our daily life. Understanding these phenomena has become a crucial field of academic research and a holy grail for investors. In this project, I aim to study and develop models to forecast and manage the risk propagation along simplified structures called dynamical networks with particular emphasis on the morphological changes occurring as back-reaction to the risk spread.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-SE - Society and Enterprise panel"], "Coordinated_in": ["Germany"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-09-01"], "Project_ID": ["750961"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["IRISH TRADITIONAL MUSIC ARCHIVE/TAISCE CHEOL DUCHAIS EIREANN LBG"], "EU_Contribution": ["EUR 187 866"], "Project_Title": ["Linked Irish Traditional Music Project"], "Total_Cost": ["EUR 187 866"], "Country": ["Ireland"], "Project_ACR": ["LITMUS"], "Technology_Description": "The LITMUS (Linked Irish Traditional Music) project will focus on the development of the first linked open data (LOD) framework tailored to the needs of Irish traditional song, instrumental music, and dance (ITM), as well as European and non-European traditional musics primarily propagated through oral transmission. LOD connects data from within & beyond knowledge domains; LOD ontologies are specially designed to represent knowledge structures and relationships. The few existing LOD music ontologies do not adequately express ITM & other oral traditions, making LITMUS significant. Project activities include ontology development, LOD infrastructure creation, & development of a publicly-accessible LOD pilot. LITMUS will impact the larger European cultural heritage community & beyond, providing a framework for other organisations to model & publish their own similar collections in LOD; reifying latent shared properties & traits anecdotally known to exist in the folk music of countries with strong socio-historical links. The researcher is uniquely positioned for implementing the LITMUS project through her combination of depth & breadth of knowledge in ITM, research in music information scholarship, & technological skills. Through LITMUS, the researcher will gain new technical skills, apply knowledge in multiple areas, gain insight into LOD industry research; synthesize current knowledge with new approaches using LOD, & gain high-level publication & presentation opportunities, thus greatly enhancing her employability in the non-academic sector. A variety of non-academic and academic audiences will be engaged in dissemination & communication of project results through presentations, demonstrations, videos, & workshops, including interdisciplinary music audiences. LITMUS will add value to ITMA's existing role as Project Partner & Content Provider for Europeana/Europeana Sounds whilst establishing ITMA as an international research focal point for LOD & traditional musics.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-SE - Society and Enterprise panel"], "Coordinated_in": ["Ireland"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-07-01"], "Project_ID": ["750814"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["GOETEBORGS UNIVERSITET"], "EU_Contribution": ["EUR 173 857,20"], "Project_Title": ["Defining the Role of Antioxidants on Cancer progression and metastasis"], "Total_Cost": ["EUR 173 857,20"], "Country": ["Sweden"], "Project_ACR": ["RAC"], "Technology_Description": "Antioxidants, by neutralizing ROS and ROS-induced DNA damages, are thought to protect against cancer. Recently this common view was challenged by the observation that antioxidants may accelerate tumor progression in mouse models of lung cancer, by turning down the DNA-damage-gH2AX-p53 signaling pathway. This study raised new questions: Are antioxidants able to induce metastasis from benign tumors, by silencing p53 expression? Are cytosolic ROS equivalent to mitochondrial ROS for lung cancer progression?", "To": ["2018-02-28, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["707700"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["COATING TECHNOLOGIES SL"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Novel industrial processes using the Atomic Layer Deposition technique"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["ALDing"], "Technology_Description": "Different from chemical vapor deposition (CVD) and physical vapor deposition (PVD), atomic layer deposition (ALD) is based on saturated surface reactions. In this case, the thin films are grown in a layer-by-layer fashion allowing sub-nanometer thickness control, low temperature depositions, good uniformity and superior step coverage on high specific surface area components compared to CVD and PVD.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-SE - Society and Enterprise panel"], "Coordinated_in": ["Spain"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-04-01"], "Project_ID": ["746954"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF LEEDS"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Robotic Manipulation Planning for Human-Robot Collaboration on Forceful Manufacturing Tasks"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["HumRobManip"], "Technology_Description": "This proposal addresses robotic manipulation planning for human-robot collaboration during manufacturing. My objective is to develop a planning framework which will enable a team of robots to grasp, move and position manufacturing parts (e.g. planks of wood) such that a human can execute sequential forceful manufacturing operations (e.g. drilling, cutting) to build a product (e.g. a wooden table). ", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["746143"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["HERIOT-WATT UNIVERSITY", "HERIOT-WATT UNIVERSITY"], "EU_Contribution": ["EUR 1 499 985"], "Project_Title": ["Deaf mobilities across international borders: Visualising intersectionality and translanguaging"], "Total_Cost": ["EUR 1 499 985"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["MobileDeaf"], "Technology_Description": "Deaf signers\u2019 international mobilities are rapidly increasing. These mobilities are unique in a number of respects: while being biologically deaf leads to certain limitations and to discrimination and inequalities, being skilled in visual language also creates possibilities and opportunities for communication across national and linguistic borders. There are two main research questions in the project. First, within contexts of international deaf spaces, how does the status of being deaf intersect with other statuses, particularly ethnicity, nationality, education, religion and gender, and which meaningful connections or accumulated inequalities occur? Second, how do deaf signers in these contexts practice and experience translanguaging, by making strategical use of multiple languages and language modalities, and International Sign? Four subprojects will focus on structurally different kinds of international deaf mobilities: (1) forced migration, (2) labour migration, (3) professional mobility, and (4) tourist mobility. The research team will be all-deaf as to maximise access to various sign languages, access to distinct deaf networks, and insights into deaf ways of living. This is a unique endeavour as most deaf-related research is hearing-led. The methodology will be ethnographic but neither logocentric nor audiocentric as visual methods (photography, video, mapping, and the production of four ethnographic documentaries) will be heavily employed, doing justice to the visual nature of sign language communication. By scrutinizing and bridging the concepts of intersectionality and translanguaging, this study will contribute to the study of growing complexity in diversity and mobility; the production/delimitation of social spaces particularly through language practices, strategies and ideologies; while engaging with issues of researchers\u2019 embodiment, positionality and engagement, concerns which are central to the so-called third wave in deaf studies.", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["714615"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH", "EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH", "UNIVERSITA DI PISA"], "EU_Contribution": ["EUR 1 876 215,30"], "Project_Title": ["Understanding the mass scales in nature"], "Total_Cost": ["EUR 1 876 215,30"], "Country": ["Switzerland", "Switzerland", "Italy"], "Project_ACR": ["NEO-NAT"], "Technology_Description": "The experimental results of the first run of the Large Hadron Collider lead to the discovery of the Higgs boson but have not confirmed the dominant theoretical paradigm about the naturalness of the electro-weak scale, according to which the Higgs boson should have been accompanied by supersymmetric particles or by some other new physics able of protecting the Higgs boson mass from quadratically divergent quantum corrections.", "To": ["2020-11-30, ongoing project |"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2015-12-01"], "Project_ID": ["669668"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["META GROUP SRL", "EUROPEAN CROWDFUNDING NETWORK", "EUROPEAN BUSINESS AND INNOVATION CENTRE NETWORK AISBL"], "EU_Contribution": ["EUR 472 468,75"], "Project_Title": ["Supporting FET projects to reach out investors"], "Total_Cost": ["EUR 472 468,75"], "Country": ["Italy", "Belgium", "Belgium"], "Project_ACR": ["FET2RIN"], "Technology_Description": "FET2RIN aims at facilitating collaborations to set the ground for the take up of FET projects by overcoming obstacles related to market outreach and accessing business leaders including entrepreneurs, early stage investors and crowdfunding communities.", "To": ["2018-11-30, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-CSA-FETTAKEUP-2015 - FET Take-Up Coordination and Support Activities 2015"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Italy"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other", "Other"], "From": ["2015-12-01"], "Project_ID": ["687110"], "Call_for_Proposal": ["H2020-FETOPEN-2015-CSA"]}, -{"Partners": ["THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Delivering better fitness estimators for wildlife ecology and management and effective monitoring"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["BetMon"], "Technology_Description": "Fitness is a key concept in basic and applied ecology, and its traits are used to assess habitat quality and derive scientific knowledge used to design and implement management and conservation measures. Assessing fitness requires considering several traits and trade-offs, and long-term data sets with individual identification that are rarely available. As a result fitness proxies such as offspring production are often used as substitute but these do not consider variation in offspring survival and lifespan, which accounts for most variation in fitness is in long-lived species, like many endangered vertebrates. Many studies, and decisions supported by them, involve unknown biases as consequence of the knowledge gap in the relationship between fitness and: the reliability of each proxy; trade-offs among different proxies; and among proxy/monitoring-effort combinations. ", "To": ["2017-05-13, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-05-14"], "Project_ID": ["659648"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["CONSIGLIO NAZIONALE DELLE RICERCHE"], "EU_Contribution": ["EUR 168 277,20"], "Project_Title": ["Anchialine caves to understand evolutionary processes"], "Total_Cost": ["EUR 168 277,20"], "Country": ["Italy"], "Project_ACR": ["ANCAVE"], "Technology_Description": "The goal of this project is to use the animal communities inhabiting anchialine environments as a model to investigate evolutionary patterns and processes in island-like marine habitats. Anchialine environments represent world-wide distributed land-locked water bodies with marine origin. They are comparable to islands for terrestrial habitats as they encompass young, discrete habitats with comparable ecological conditions to the sea, thus providing independent replicates of comparable evolutionary processes. All anchialine habitats previously investigated harbor high endemism, disharmonic communities, species with unique set of troglomorphic features, and old animal lineages interpreted as living fossils. In the four research parts of this project, we will test each of these observations and the processes related to them by analyzing large data sets with both macroecological and phylogenetic methods and a broad theoretical perspective from the field of evolutionary ecology, comparative evolution and island biogeography. This will facilitate to link the ecological and evolutionary processes observed in these habitats (easy to isolate and test due to the discrete and young nature of anchialine habitats) with those affecting oceanic ecosystems, providing a tool for a deeper understanding of the marine biota. Whereas similar approaches are well characterized in terrestrial environments (e.g. island), they are missing in the ocean, obscuring our understanding of the processes occurring there.", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations"], "From": ["2017-11-01"], "Project_ID": ["745530"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITEIT LEIDEN"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["Miniaturised Metabolomics Platform for Microvascular Research"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["METAFORA"], "Technology_Description": "Preventing and treating progressive microvascular loss (i.e. rarefaction) is a major challenge in cardiovascular medicine. Microvascular disease is a multifactorial disease with no effective treatment. Long-term exposure to adverse metabolic and haemodynamic conditions such as hypertension, obesity and diabetes can cause microvascular destabilisation, loss of tissue capillaries, and eventual organ failure. Interestingly, not all diabetic patients develop kidney failure. The missing link to developing effective strategies for treating multifactorial diseases, including microvascular disease, is detailed mechanistic insight into the relationship between disease pathogenesis at the organ/cellular level at the systemic/organism level. ", "To": ["2018-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["709077"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITEIT LEIDEN"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["Microscopic Surface Dynamics of Pt and Pt Alloy Electrocatalysts under operation conditions"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["DYNECAT"], "Technology_Description": "By employing the in-situ electrochemical video-rate scanning tunneling microscopy (STM) at well-defined single crystal electrodes, we are going to study the surface dynamics of the atoms on Pt(111), Pt(553), Pt(533), Pt(111)-Cu and Cu/Pt(111) surface alloy in the absence and presence of oxygen gas, with the aim to probe and understand the restructuring of Pt and Pt alloy catalyst of the fuel cell cathodes under the operation conditions. Simultaneously, in-situ electrochemical surface Raman spectroscopy will be used to identify the surface species and their interaction with electrodes, using a version employing shell-isolated nanoparticles that is suitable for single-crystal electrodes. On the basis of the observations of STM and Raman spectroscopy, theoretical calculations based on density functional theory (DFT) and Monte Carlo simulations will be carried out to understand the surface electronic structures and to mimic dynamical migrations of the surface atoms. This should yield deep insight into the essential dynamic properties and the impact on the restructuring of these electrocatalysts under operation conditions.", "To": ["2017-03-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-04-01"], "Project_ID": ["661145"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["AARHUS UNIVERSITET"], "EU_Contribution": ["EUR 212 194,80"], "Project_Title": ["Understanding Social-Ecological Systems: Coupling population and satellite remotely sensed environmental data to improve the evidence base for sustainable development"], "Total_Cost": ["EUR 212 194,80"], "Country": ["Denmark"], "Project_ACR": ["USES"], "Technology_Description": "In developing countries the majority of rural communities rely on natural resources and environmental products for food, fuel, building materials and medicines. Rapidly changing socioeconomic conditions can have important consequences for environmental resources and ecosystem services. Consequently, the pressure that natural resources experience from population growth is a significant barrier to sustainable human development. This research project will broaden the approach to sustainable development research by studying population-environment relationships using data with unrivalled spatial and temporal resolutions. The objectives of the research are to identify: (1) How satellite data can be used to estimate aspects of environmental resources and ecosystem services important for livelihoods; (2) the relationships between household poverty and remotely sensed environmental conditions? And are these relationships consistent at different time periods? and; (3) how changes in poverty relate to changes in environmental conditions and vice versa? To study these relationships household panel survey data and remotely sensed environmental data will be coupled using GIS and non-parametric Classification and Regression Trees (CART) and random forests models which can handle and represent meaningfully the complex, nonlinear relationships between poverty and environment. The project will contribute to the Horizon 2020 aim of furthering sustainability science by exploring how changes in society and the environment are linked and contribute to society beginning to think about interventions to managing environmental resources which could contribute to development and to understand the changes likely in environmental resources when development occurs. It will contribute to the Work Programme as the fellow will gain new skills and training in geospatial and computational ecology and become an EU leading specialist in a research field with a lot of growth potential.", "To": ["2018-02-13, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-11-01"], "Project_ID": ["656811"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITEIT LEIDEN", "UNIVERSITEIT LEIDEN"], "EU_Contribution": ["EUR 1 499 522"], "Project_Title": ["Forging Advanced Liquid-Crystal Coronagraphs Optimized for Novel Exoplanet Research"], "Total_Cost": ["EUR 1 499 522"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["FALCONER"], "Technology_Description": "The 39-m European Extremely Large Telescope (E-ELT) has the potential to directly observe and characterize habitable exoplanets, but current technologies are unable to sufficiently suppress the starlight very close to the star. I propose to develop a novel instrumental approach with breakthrough contrast performance by combining coronagraphs based on brand-new liquid crystal technology, and sensitive imaging polarimetry. The novel coronagraphs will provide an achromatic rejection of starlight even right next to the star such that exoplanets can be imaged efficiently in broadband light and characterized through spectropolarimetry. The coronagraphs will incorporate focal-plane wavefront sensing and polarimetry to achieve an ultimate contrast of 1E-9, which will enable the E-ELT to observe habitable exoplanets.", "To": ["2021-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-04-01"], "Project_ID": ["678194"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "LINKOPINGS UNIVERSITET", "IQUADRAT INFORMATICA SL", "HERIOT-WATT UNIVERSITY", "UNIVERSITAT POLITECNICA DE CATALUNYA", "TECHNISCHE UNIVERSITAET DRESDEN", "SIRADEL", "ERICSSON AB", "EDUCATIONAL OTE AE", "TTI NORTE, S.L."], "EU_Contribution": ["EUR 3 858 492,24"], "Project_Title": ["Innovative Architectures, Wireless Technologies and Tools for High Capacity and Sustainable 5G Ultra-Dense Cellular Networks"], "Total_Cost": ["EUR 3 858 492,24"], "Country": ["France", "Sweden", "Spain", "United Kingdom", "Spain", "Germany", "France", "Sweden", "Greece", "Spain"], "Project_ACR": ["5G Wireless"], "Technology_Description": "The fifth-generation (5G) is coming.Quo vadis 5G?What architectures, network topologies and technologies will define it?Are methodologies to the analysis, design and optimization of current cellular networks still applicable to 5G? 5Gwireless is the first integrated and multi-disciplinary training-through-research network of ESRs and Senior Supervisors fully committed to re-architecting current cellular principles aiming at making 5G a reality, it will define and optimize radically-changing architectures and technologies leading to a wholesale re-thinking of cellular operational principles & architectures, network topologies, transmission technologies and methods to their analysis, design and optimization. It will recruit 15 ESRs having the objective of conducting top-notch research at national, European and international levels.ESRs will receive personalized training and will conduct theoretical and applied research on fundamental challenges to the development of 5G systems and networks. According to the 5G Public-Private Partnership (5GPPP) recently formed by the EU, 5G networks need to be designed, engineered and optimized by relying on innovative technologies capable of providing 1000 times higher capacity and a 90% reduction in energy consumption compared to the status quo.Such a fundamental and radical paradigm-shift in network design and architecture requires cross-sectoral skills&background and can very unlikely be realized by researchers that have not received personalized training on innovative technologies and adequate methodological tools to their analysis.5Gwireless' mission is to create a vibrant EU-based training and research environment for young researchers aiming at designing architectures, systems and algorithms for building the 5G cellular network of tomorrow. 5Gwireless is first step in that direction having the long-term target of preparing the first highly-selected & trained class of competent academic researchers and industrial professionals.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["641985"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["UNIVERSITAET BREMEN", "UNIVERSITAET INNSBRUCK", "CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL", "AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS", "CONTROL Y PROSPECCIONES IGEOTEST SL", "INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER", "ISTITUTO NAZIONALE DI OCEANOGRAFIA E DI GEOFISICA SPERIMENTALE", "CONSIGLIO NAZIONALE DELLE RICERCHE", "STIFTELSEN NORGES GEOTEKNISKE INSTITUTT", "NATURAL ENVIRONMENT RESEARCH COUNCIL", "UNIVERSITY OF DURHAM"], "EU_Contribution": ["EUR 3 894 543,36"], "Project_Title": ["Submarine LAndslides and Their impact on European continental margins"], "Total_Cost": ["EUR 3 894 543,36"], "Country": ["Germany", "Austria", "Germany", "Spain", "Spain", "France", "Italy", "Italy", "Norway", "United Kingdom", "United Kingdom"], "Project_ACR": ["SLATE"], "Technology_Description": "The over-arching aim of the SLATE ETN is (i) to understand key factors triggering submarine landslides, the subsequent motion and evolution of failed material, and ensuing geohazards eg tsunamis and (ii) to integrate an innovative broad range of scientific disciplines and private sector needs into a novel training and co-supervision of 15 ESRs. ", "To": ["2021-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["721403"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["UNIVERSITEIT LEIDEN", "UNIVERSITEIT LEIDEN"], "EU_Contribution": ["EUR 1 991 231"], "Project_Title": ["Rethinking Disability: the Global Impact of the International Year of Disabled Persons (1981) in Historical Perspective"], "Total_Cost": ["EUR 1 991 231"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["DISABILITY"], "Technology_Description": "Approximately 10% of the world\u2019s population is estimated to be disabled and this number is expected to rise in the next few decades. People in different cultural settings ascribe different meanings to disability; consequently, its repercussions are both culturally contingent and universal. This project brings together the local and global dimensions of disability and examines the interaction, tension and conflict between these two aspects by undertaking the first comprehensive study of the far-reaching political, societal and cultural implications of the International Year of Disabled Persons (IYDP) which was organized under the auspices of the United Nations in 1981. A landmark event which appears to have gone virtually unrecognized in scholarship; the IYDP was the first occasion to place disability into a global context by endorsing it authoritatively as a human rights issue and thereby raising the question as to how the concept may be understood in a multicultural world. There will be four closely-related objectives: 1. to examine the IYDP\u2019s impact on human rights discourses and to scrutinize their applicability within global settings; 2. to document the IYDP\u2019s contribution to emancipation and social change and to consider the different trajectories of emancipation in various parts of the world; 3. to assess the ways in which the IYDP influenced everyday life experiences, galvanized identity formation and inspired the emergence of a distinct subculture; 4. to analyze the transnational exchanges and knowledge transfer in conjunction with the IYDP and to examine how the Western oriented discourses penetrating the developing world interacted with the local environment. The project\u2019s innovative contribution and academic impact lies in connecting the IYDP to broader political, social and cultural processes in the last quarter of the twentieth century and thereby bringing disability in a global context to the attention of mainstream historical scholarship.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["648115"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["UNIVERSITEIT LEIDEN", "UNIVERSITEIT LEIDEN"], "EU_Contribution": ["EUR 1 075 109"], "Project_Title": ["Democratic Secrecy: A Philosophical Study of the Role of Secrecy in Democratic Politics"], "Total_Cost": ["EUR 1 075 109"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["DEMSEC"], "Technology_Description": "Transparency in politics is the mantra of democratic governance. Should state secrecy, such as classified intelligence programs or closed-door political bargaining be abolished? Despite its revered status, many feel that complete transparency would undermine effective functioning of governments. Take the public responses to the Wikileaks disclosures: many of the disclosures were assessed favorably, but few people defended the idea of total transparency that inspired them.", "To": ["2020-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-08-01"], "Project_ID": ["639021"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["UNIVERSITEIT LEIDEN", "UNIVERSITEIT LEIDEN"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["The neural basis of prosocial development in adolescence"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["PROSOCIAL"], "Technology_Description": "Adolescence is an important transition period in life, where individuals gain independence from their caregivers and develop into adults who pursue their own goals. Our understanding of this transition period has benefited from two decades of research on brain development, in which it was discovered that adolescence represents a period of risk for heightened emotional reactivity, and that the developing brain in adolescence is much more plastic than previously thought. ", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["681632"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["UNIVERSITEIT LEIDEN", "UNIVERSITEIT LEIDEN"], "EU_Contribution": ["EUR 2 460 500"], "Project_Title": ["Father Trials: Hormonal and Behavioral Experiments on Prenatal and Postnatal Parenting"], "Total_Cost": ["EUR 2 460 500"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["FATHER TRIALS"], "Technology_Description": "Fathers have largely been neglected in parenting research -- although they constitute about 50% of parents. The aim of the proposed project is to test the hypothesis that fathers\u2019 parenting is under hormonal control and can be changed by behavioral and hormonal interventions. I propose a series of randomized controlled trials (RCT) focusing on a critical phase of parenthood: the transition to having the first baby. I will test whether experiments that modulate oxytocin and testosterone levels enhance fathers\u2019 neural processing of infant signals and of threats to the infant and stimulate fathers\u2019 parenting quality and involvement in parenting. ", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["669249"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["UNIVERSITEIT LEIDEN", "UNIVERSITEIT LEIDEN"], "EU_Contribution": ["EUR 2 500 000"], "Project_Title": ["Cognitive control in context: Neural, functional, and social mechanisms of metacontrol"], "Total_Cost": ["EUR 2 500 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["Metacontrol"], "Technology_Description": "Human behavior is commonly understood as emerging from a struggle between will and habit, i.e., between \u201cintentional\u201d processes driven by the current goal and \u201cautomatic\u201d processes driven by available stimuli. This scenario suggests that it is mainly the goal-related processes that render behavior adaptive. Based on a novel theoretical framework (the Metacontrol State Model, combined with the Theory of Event Coding) that is motivated by recent behavioral and neuroscientific observations, I suggest an alternative view and argue that people can control the relative contributions of goal-driven and stimulus-driven processes to decision-making and action selection. In particular, people regulate the interaction between these processes by determining the ratio between (goal) persistence and flexi-bility, depending on task, situation, and personal experience\u2014a process that I refer to as \u201cmetacontrol\u201d. The project aims to identify and trace individual \u201cmetacontrol policies\u201d (biases towards persistence or flexibility) and task- and condition-specific changes therein by means of behavioral, computational, and neuroscientific techniques, and by using virtual-reality methods. I shall study, account for, and try predicting individual differences in the choice and implementation of such policies, identify and explain the cognitive and social consequences of adopting a particular policy, and investigate whether and how people can adopt meta\u00accontrol policies from others\u2014either intentionally or automati-cally. I shall also study whether and to what degree people use situational cues to automatize the implementation of suitable policies, and whether often-used, highly practiced policies can become chron-ified and turn into a trait-like processing style, as suggested by cultural studies.", "To": ["2021-11-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-12-01"], "Project_ID": ["694722"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["UNIVERSITEIT LEIDEN", "UNIVERSITEIT LEIDEN"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Unravelling cross-presentation pathways using a chemical biology approach"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["Crosstag"], "Technology_Description": "Immune therapies are therefore currently being pursued to reinvigorate the immune reaction against tumours. This is not trivial, as the right type of immune cells must be activated against a tumour-specific antigen. One method to achieve this is by targeting tumour antigens to certain cross-presentation-promoting receptors on antigen presenting cells. The most intriguing of these is the mannose receptor (MR) as the method by which it does this is unknown. ", "To": ["2020-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-05-01"], "Project_ID": ["639005"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["UNIVERSITEIT LEIDEN", "UNIVERSITEIT LEIDEN"], "EU_Contribution": ["EUR 2 300 962"], "Project_Title": ["Exoplanet atmospheres as indicators of life: From hot gas giants to Earth-like planets"], "Total_Cost": ["EUR 2 300 962"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["EXOPLANETBIO"], "Technology_Description": "This is a proposal to use a new ground-breaking spectroscopic technique to study the atmospheres of extrasolar planets. Understanding planet atmospheric processes and their evolutionary histories is crucial for unambiguously identifying biomarker gases, and forms the main driver behind the enormous surge in exoplanet atmospheric research. ", "To": ["2021-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["694513"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["UNIVERSITEIT LEIDEN"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["Cross-talk between inflammation and autophagy in tuberculosis"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["Inflammafish"], "Technology_Description": "The increasing occurrence of multidrug-resistant Mycobacterium tuberculosis strains makes tuberculosis (TB) a key priority for infectious disease research. Inflammation and autophagy are two fundamental processes critical to TB pathogenesis. Accumulating evidence shows that TB disease is worsened by deregulation of the inflammatory response. On the other hand, autophagy has recently emerged as a crucial host defence mechanism. Autophagy counteracts the ability of mycobacteria to survive inside host cells and targets them for degradation. Autophagy is also thought to control the inflammatory response. However, the interaction between inflammation and autophagy in host defence against TB remains unclear. The aim of my proposal is to use the well-established zebrafish model of TB to gain insight into this key question. Recently, the host laboratory discovered that the DNA damage-regulated autophagy modulator (DRAM1) protects against TB in the zebrafish model. They also implicated this important autophagy regulator in inflammation, as it strongly affects expression of interleukin-1beta (IL1B). I have specific expertise in studying IL1B-mediated inflammation in zebrafish. Thus the proposed project will be a great synergy between me and the host laboratory, which is leading in zebrafish infectious disease research. I will determine how modulation of autophagy or manipulation of IL1B levels reciprocally influence each other during TB disease. The zebrafish model provides excellent tools to visualize these processes in vivo. Furthermore, I will take advantage of the host\u2019s expertise in RNA sequencing and proteomics to study genome-wide effects of autophagy modulation on the inflammatory response. A secondment will allow me to compare results in the TB model with a damage-induced inflammation model. The project will provide new insights into regulatory pathways that could potentially be intervened in treatment of TB or other inflammatory diseases with common characteristics.", "To": ["2018-01-17, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-01-18"], "Project_ID": ["655424"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE UNIVERSITY OF LIVERPOOL"], "EU_Contribution": ["EUR 241 169,40"], "Project_Title": ["How to help the hive? Incidence and impact of heritable microbes on bee health"], "Total_Cost": ["EUR 241 169,40"], "Country": ["United Kingdom"], "Project_ACR": ["BeeSymOverSpace"], "Technology_Description": "Honey bees provide both economic and societal benefits, from the honey and other commodities that they produce to the pollination services they provide. The loss of honey bee colonies and the current threats to their health are of considerable concern to bee-keepers and biologists alike. This project seeks to examine how a particular aspect of honey bee biology \u2013 the symbiotic microbiome \u2013 impacts upon honey bee health. Studies in other systems reveal heritable microbes as important modulators of disease susceptibility. This project will utilize the extensive network of bee samples across the US and UK to establish geographical patterns of heritable microbe presence in bees, and links to apiculture practice. It will then use state of the art transcriptomic and genomic approaches to establish the links between Arsenophonus, a heritable symbiont known in bees, and bee health. It will then, combine with professional agencies responsible for bee health to use these results to modify apiculture practice to establish better bee husbandry. Aside the research science completed, the project will train an EU scientist in state of the art genomic technologies and translation from discovery to applied science. It will further transfer the training gained to EU hosts, both in discovery science and application.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["704382"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITEIT LEIDEN", "UNIVERSITEIT LEIDEN"], "EU_Contribution": ["EUR 1 999 733"], "Project_Title": ["Persia and Babylonia: Creating a New Context for Understanding the Emergence of the First World Empire"], "Total_Cost": ["EUR 1 999 733"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["Persia and Babylonia"], "Technology_Description": "The Persian Empire (539-330 BCE) represented a new political order in world history. At its height, it united a territory stretching from present-day India to Libya. It was three times as large and twice as long-lived as the previously most successful polity (Assyria), and it would take 2,000 years before significantly larger empires emerged in early modern Eurasia. ", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["682241"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["UNIVERSITEIT LEIDEN"], "EU_Contribution": ["EUR 174 864,60"], "Project_Title": ["The Power of Silence: A Medical Anthropological Approach to AIDS Care Narratives"], "Total_Cost": ["EUR 174 864,60"], "Country": ["Netherlands"], "Project_ACR": ["AIDSsilences"], "Technology_Description": "Despite the widespread availability of antiretroviral medication, the global AIDS epidemic has not been halted yet and stigmatization of people living with HIV and AIDS continues in most parts of the world. While the social scientific analysis of narratives of people living with HIV/AIDS (PLWHA) has proven crucial in understanding challenges in AIDS care worldwide, the silences that structure such narratives remain under-theorized. Current studies signal that silences may be defenses and active strategies rather than passive responses to stigma, but critical questions remain on how to study, conceptualize and interpret what is unspeakable and unspoken, and sometimes even unthinkable. ", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["707562"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["FUNDACIO CENTRE DE REGULACIO GENOMICA", "FUNDACIO INSTITUT DE CIENCIES FOTONIQUES", "EUROPEAN MOLECULAR BIOLOGY LABORATORY", "THE HEBREW UNIVERSITY OF JERUSALEM", "LABORATORY IMAGING SPOL SRO", "Idea Bio-Medical Ltd."], "EU_Contribution": ["EUR 3 988 752,50"], "Project_Title": ["CellViewer: super-resolution systems microscopy to assess pluripotency and differentiation of stem cells at single cell level"], "Total_Cost": ["EUR 3 988 752,50"], "Country": ["Spain", "Spain", "Germany", "Israel", "Czech Republic", "Israel"], "Project_ACR": ["CellViewer"], "Technology_Description": "In this ambitious and multi-disciplinary proposal, we aim to develop new technologies that will allow us to visualize in single cells, in parallel and at the systems level, DNA, mRNAs and proteins with nanoscale resolution. We will refer to these novel technologies as the \u2018CellViewer\u2019: a unique cutting-edge high-throughput super-resolution (SR) microscopy approach (including new hardware and software development) to collect at high-resolution a large amount of spatial and dynamic information in single cells. \u2018CellViewer\u2019 will allow us to study the mechanisms of mouse embryonic stem cell (mESC) self-renewal and differentiation upon application of specific stimuli, as a specific test case. We will analyse in single cells with high throughput, DNA remodelling at multiple specific gene loci and their corresponding production, distribution and kinetics of mRNA and protein products. We will collect a large amount of dynamic and nanoscale spatial information that will lead us to build predictive models of the phenotypic output from specific input stimuli. In turn, we will be able to develop a mechanistic understanding of how mESCs maintain their stemness or commit to differentiation. The partners of CellViewer are internationally recognized experts from academia and industry in the fields of stem cell and chromatin biology, super-resolution microscopy, quantitative modelling of biological systems, and hardware and software development. This team as a whole is uniquely suited to bring Systems Biology into the era of single cell analysis, which will be a paradigm shift in the way cellular systems will be studied.", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-1-2014 - FET-Open research projects"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-02-01"], "Project_ID": ["686637"], "Call_for_Proposal": ["H2020-FETOPEN-2014-2015-RIA"]}, -{"Partners": ["UNIVERSITEIT LEIDEN"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["Isis, Images and Agency. The Creation, Use and Perception of Religious Iconography Concerning the Egyptian Gods in the Hellenistic and Roman Worlds"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["IsImAg"], "Technology_Description": "\"In the Hellenistic and Roman worlds, the Egyptian goddess Isis was remarkably popular along with the deities related to her, such as Sarapis, Harpocrates and Anubis. Tens of thousands of objects, from a wide variety of contexts and periods, convey images that attest to the immense success of these cults. Both rich and coherent, this corpus of transcultural imagery provides an excellent laboratory for the study of the creation, use and perception of ancient figurative media, especially in terms of agency. Previous research on this religious iconography has only wielded a fragmented vision, paying little attention to contexts and media. However, these images can only be understood in relation to one another and as part of their sociocultural and religious networks. Since 2013, reconstituting this overview has been the aim of a Thesaurus whose catalogues gather all Isiac images for every kind of medium, highlighting the contextualised objects and questioning what they meant and did. The progress of this collective undertaking allows me now to present a research project crucial to many categories of historians working on visual (material) culture. By reconstituting the history of Isiac images throughout various types of production, the Thesaurus demonstrates how figurative systems were constantly interacting and evolving during Antiquity. It enables us to ask new questions on the creation, use and perception of these object-images from both a synchronic and diachronic perspective. The synthesis emerging will form a \"historical grammar\" revealing the functioning of this figurative culture and its impact on ancient societies. With the largest part of the Thesaurus now available, Leiden University provides the best current academic context for the more interpretative and synthesising parts of the research. By partaking in a more conceptual research culture, this experience will have a decisive impact on my scientific development and will open up numerous new perspectives.\"", "To": ["2019-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-02-01"], "Project_ID": ["702875"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITEIT LEIDEN", "UNIVERSITEIT LEIDEN"], "EU_Contribution": ["EUR 1 500 000"], "Project_Title": ["Biomimetic Copper Complexes for Energy Conversion Reactions"], "Total_Cost": ["EUR 1 500 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["Cu4Energy"], "Technology_Description": "Water oxidation (WO) and oxygen reduction (OR) are crucial reactions to produce and to consume solar fuels. It is important that WO and OR occur with very high catalytic rates with only a very small thermodynamic driving force (i.e. a small overpotential). In these terms, natural catalysts perform significantly better than the artificial systems. Especially the copper enzyme Laccase operates fast at a low overpotential. In principle one could use the same design principles used in the enzymatic systems to produce artificial catalysts for OR and WO. It is envisioned that for the most ideal OR and WO catalysts:", "To": ["2020-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-05-01"], "Project_ID": ["637556"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["UNIVERSITEIT LEIDEN", "UNIVERSITEIT LEIDEN"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Membrane fusion mediated dermal allergy immunotherapy"], "Total_Cost": ["EUR 150 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["DermalTherapy"], "Technology_Description": "In this project we aim to develop a new delivery platform for allergy vaccines with a high efficacy and a high safety profile combining membrane fusion-mediated delivery and microneedle-based dermal delivery.", "To": ["2016-08-31, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2014 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["665684"], "Call_for_Proposal": ["ERC-2014-PoC"]}, -{"Partners": ["ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE", "KOBENHAVNS UNIVERSITET", "UNIVERSITEIT LEIDEN"], "EU_Contribution": ["EUR 2 371 132"], "Project_Title": ["From Fermi to Planck : a bottom up approach"], "Total_Cost": ["EUR 2 371 132"], "Country": ["Switzerland", "Switzerland", "Denmark", "Netherlands"], "Project_ACR": ["NuBSM"], "Technology_Description": "The Standard Model of particle physics is a hugely successful theory that has been tested in experiments at ever increasing energies, culminating in the recent discovery of the Higgs boson. Nevertheless, some major riddles cannot be addressed by the Standard Model, such as neutrino oscillations, the existence of Dark Matter, the absence of antimatter in the Universe. New fundamental principles, interactions and unknown yet particles are required to address these questions. Much of the research done during the last three decades on physics \u2018beyond the Standard Model\u2019 (BSM) has been driven by attempts to find a \u2018natural\u2019 solution of the hierarchy problem: why the Planck and the electroweak scales are so different. The most popular approaches to this problem predict new particles with the masses right above the electroweak scale.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-10-01"], "Project_ID": ["694896"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["UNIVERSITEIT LEIDEN", "UNIVERSITEIT LEIDEN"], "EU_Contribution": ["EUR 1 999 960"], "Project_Title": ["Embedding Conquest: Naturalising Muslim Rule in the Early Islamic Empire (600-1000)"], "Total_Cost": ["EUR 1 999 960"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["EMBEDDING CONQUEST"], "Technology_Description": "What made the early Islamic empire so successful and have we missed the story by neglecting crucial evidence? The 7th-century Arab conquests changed the socio-political configurations in the Mediterranean and Eurasia forever. Yet we do not really know how the Arabs managed to gain dominance of this vast, ethnically, religiously and linguistically diverse area which had its own, long imperial traditions, and to make this a sustainable enterprise. What built the empire, and what held it together? Scholarship to date has overwhelmingly relied on \u2018literary\u2019 sources in Arabic (e.g. chronicles, legal treatises, theological tracts), composed centuries after the conquests and shaped by court politics at their time of writing. This has created a false impression of the embedding of Muslim rule as a top-down process, directed from the centre, built on military coercion and control through administrative systems. Now, however, \u2018documentary\u2019 sources in multiple languages on papyrus, leather and paper from all over the empire (e.g. letters, contracts, fiscal accounts, petitions, decrees, work permits) are becoming increasingly available, with the PI in an internationally leading role. These sources, whose impact has been limited by linguistic and disciplinary boundaries, offer a direct, contemporary view of how the empire worked on the ground, and how political and social structures were experienced, modified and appropriated by its subjects.This project will uniquely incorporate all available documents reflecting Muslim rule from the first 400 years of Islam, to reconstruct the system of social relations that enabled the crucial transition from a conquest society to a political organism that survived the breakdown of central caliphal control, and remains the region\u2019s benchmark model today. It will critically advance our understanding of a world historical event, make a radically new contribution to empire studies, and connect and synergise area studies and disciplinary inquiry.", "To": ["2021-12-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["683194"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["UNIVERSITA CA' FOSCARI VENEZIA"], "EU_Contribution": ["EUR 180 277,20"], "Project_Title": ["Nanomaterials Ecological Risk Assessment: A study of the long-term effects and risks of nanoscale Iron Oxide used in plastic composites in the aquatic environment"], "Total_Cost": ["EUR 180 277,20"], "Country": ["Italy"], "Project_ACR": ["NanoERA"], "Technology_Description": "The nanoform of Iron Oxide (n-Fe2O3) is a large-volume substance used in pigments. Nanoscale Fe2O3 pigments are used to a significant extent in consumer products such as household appliances made of coloured plastic composites. This application implies high probability of n-Fe2O3 release into the aquatic environment (especially during end-of-life processing of the plastics), where n-Fe2O3 may pose risks to freshwater and sediment organisms. Presently, very little is known about the biological interactions and the ecological risks of n-Fe2O3, as the available information addresses only short-term effects of pristine n-Fe2O3. Therefore, the goal of NanoERA is to develop concepts and methods, and to generate data to predict the long-term ecological effects and risks of n-Fe2O3 (fragments) released from end-of-life processing of a coloured plastic composite into the aquatic environment and to compare them to the pristine n-Fe2O3 used to produce the composite. In order to achieve this, the fellow will analyse how the physicochemical properties of the n-Fe2O3 (fragments) change in environmental (i.e. freshwater and sediment) and biological (cell culture) media and how these changes affect the biological interactions of these materials in aquatic organisms. The generated ecotoxicological effects data will be used to derive dose-response relationships and to quantitatively estimate the long-term ecological risks of the n-Fe2O3 (fragments). ", "To": ["2017-07-02, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-07-03"], "Project_ID": ["660960"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITEIT LEIDEN", "UNIVERSITEIT LEIDEN"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Empowering expectations for health and disease: Development of a pioneering training tool"], "Total_Cost": ["EUR 150 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["TRAIN-HEAL-TH"], "Technology_Description": "Expectations about health and disease are known to directly affect health and treatment outcomes. In the EXPECT-HEALTH project, my research group is unravelling the central mechanisms of how expectations affect immune and endocrine responses and related health outcomes, through the use of pioneering multidisciplinary methods in healthy and clinical populations. Ultimate goal of gaining this knowledge is to apply it in innovative therapeutic interventions. ", "To": ["2018-01-31, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2015 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-08-01"], "Project_ID": ["692671"], "Call_for_Proposal": ["ERC-2015-PoC"]}, -{"Partners": ["NATURAL ENVIRONMENT RESEARCH COUNCIL"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Nanomaterial surface interactions at the molecular level and their impact on ecotoxicity"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["MolNANOtox"], "Technology_Description": "As nanotechnology continues to advance at an exponential rate, new products are continuously introduced into the market for research and consumer use. Engineered nanomaterials (ENMs), the functional components in these products, are often specifically designed to exploit the unique properties that nanomaterials exhibit; however, there is a widespread uncertainty on how these new properties may also potentially translate into novel risk issues in the environment. In particular, their high specific surface area and surface reactivity may promote distinct interactions with organisms particularly at the lower trophic levels. This can depend on both the intrinsic and extrinsic properties of ENMs, and can be affected by the formation of an \u201ceco-corona\u201d, which is composed of environmentally derived macromolecules from the milieu in which the ENMs are exposed that adsorb to the ENMs surface. However, understanding these interactions at the molecular level and their mechanistic consequences are severely limited and technically challenging, requiring a cross discipline approach. This project aims to address this knowledge gap by uncovering the underlying mechanisms for the formation and persistence of eco-coronas on a range of ENMs by combining fundamental ENM chemistry, environmental toxicology, advanced optical and mass spectroscopy and imaging techniques. In particular, this project will apply surface enhanced spectroscopic methods to characterise eco-corona composition and evolution and how this affects ENM interactions with, and impact upon unicellular organisms. By correlating the eco-corona composition with uptake route (or accumulation at external membrane) and toxicity response, and by investigating how these ENMs are partitioned within model species, the project proposes to identify the molecular basis that determines the fate and toxicology of ENMs in the environment.", "To": ["2017-10-04, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations"], "From": ["2015-10-05"], "Project_ID": ["660565"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITEIT LEIDEN", "UNIVERSITEIT LEIDEN"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Development of a potent dual GCS/GBA2 inhibitor as a best in class Gaucher therapeutic"], "Total_Cost": ["EUR 150 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["Sphingolead"], "Technology_Description": "Gaucher disease (GD) is an autosomal recessive disorder caused by deficient activity of acid glucosylceramidase (GBA1). Most patients feature a non-neuronopathic (type 1) course of disease and are treated by either enzyme replacement therapy (ERT \u2013 administration of recombinant GBA1) or substrate reduction therapy (SRT \u2013 treatment with the iminosugar, Zavesca or the ceramide mimic, Eliglustat \u2013 inhibitors of glucosylceramide synthase (GCS)). These therapeutic agents do not prevent neurological symptoms in patients suffering from neuronopathic Gaucher forms (types 2/3) and there is thus an unmet medical need for these patients. Potent GCS inhibitors reduce glucosylceramide (GlcCer), the substrate of GBA and the storage material in Gaucher, and also higher glycosphingolipids including gangliosides and globosides, the causative storage materials in Tay-Sachs disease, GM1 gangliosidosis and Fabry disease. We have found a highly attractive lead, BiPheDNM 7 (Figure C below), which we plan to further develop towards a phase I/II clinical candidate. This proof of concept project will result in a packet comprising this lead molecule, accompanied by all the relevant data and tools to start phase I/II clinical development together with a pharmaceutical partner.", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2015 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["693039"], "Call_for_Proposal": ["ERC-2015-PoC"]}, -{"Partners": ["UNIVERSITEIT LEIDEN"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["Rare Earth Supply Chain and Industrial Ecosystem: A Material Flow Assessment of European Union"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["REE Value Chain"], "Technology_Description": "Europe is the leading importer and consumer of rare earth minerals both in mineral and applied forms. Europe is almost dependent on others for imports of these mineral resources, despite the fact that engineering and manufacturing are backbone of many European economies. The criticality of these minerals were highlighted in European Commission\u2019s Report of the Ad hoc Working Group on defining critical raw materials published in 2010 as well as 2014. ", "To": ["2017-09-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["656998"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITEIT LEIDEN"], "EU_Contribution": ["EUR 242 929,80"], "Project_Title": ["Predicting Cardiotoxicity Induced by Kinase Inhibitors: From Systems Biology to Systems Pharmacology"], "Total_Cost": ["EUR 242 929,80"], "Country": ["Netherlands"], "Project_ACR": ["CARDIOTOX"], "Technology_Description": "Kinase inhibitors (KIs) are a major class of highly effective anti-cancer drugs. Unfortunately, therapeutic use of KIs is often associated with cardiotoxicity (CT), a serious adverse condition which limits their use. This fellowship aims to develop mathematical systems pharmacology models for KI-induced CT. These models will be used to identify predictive CT signatures that will allow to decrease CT risk of new KIs. This innovative multi-disciplinary approach consists of integrating mathematical systems pharmacology modelling, with state-of-the-art experimental data generation. To this aim, KIs with different magnitudes of CT will be selected based on clinical adverse event databases. Human cardiomyocytes derived from pluripotent stem cells will then be treated with the selected KIs and in combination with CT modifying drugs. The effect of these treatments on changes on untargeted mRNA and protein expression will be measured and then analyzed using network modelling. This approach allows identification of key regulatory proteins. The selected proteins will then be quantified over time along with cardiomyocyte health markers. With this data, dynamical models will be developed to capture the relationship between exposure to KIs and the effects on protein expression and cardiomyocyte health over time. Ultimately these models will allow generation of predictive network-based dynamically-weighted signatures for CT.", "To": ["2018-12-05, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-12-06"], "Project_ID": ["661588"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITA DI PISA", "Consortium Ubiquitous Technologies S.c.a.r.l.", "UNIVERSITAT ROVIRA I VIRGILI", "GENERATION RFID S.L.", "INSTITUT POLYTECHNIQUE DE GRENOBLE", "ARDEJE SARL"], "EU_Contribution": ["EUR 913 500"], "Project_Title": ["ChiplEss MultisEnsor Rfid for GrEen NeTworks"], "Total_Cost": ["EUR 913 500"], "Country": ["Italy", "Italy", "Spain", "Spain", "France", "France"], "Project_ACR": ["EMERGENT"], "Technology_Description": "EMERGENT takes up the broader scope of Marie Sk\u0142odowska-Curie Research and Innovation Staff Ex-change Scheme of promoting knowledge-sharing-based cooperation and moves its steps forward to actual-ly support and facilitate the movement of skilled people between academia and industry committed to work on a research topic dealing with green chipless RFID tags and sensors.", "To": ["2017-12-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Other", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["645771"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI MACERATA", "UNIVERSITEIT UTRECHT", "MILITOS SYMVOULEUTIKI A.E.", "MECCANO SPA", "EUROPEAN QUALITY INSTITUTE SRL", "OULUN YLIOPISTO", "STICHTING WAAG SOCIETY", "OULUN KAUPUNKI", "STEFAN MARZELLI", "UNIVERSITY OF ULSTER", "STICHTING HAS KENNISTRANSFER EN BEDRIJSOPLEIDINGEN", "FOOD NATION CIC", "TARAS SHEVCHENKO NATIONAL UNIVERSITY OF KYIV"], "EU_Contribution": ["EUR 828 000"], "Project_Title": ["Grey and green in Europe: elderly living in urban areas"], "Total_Cost": ["EUR 828 000"], "Country": ["Italy", "Netherlands", "Greece", "Italy", "Italy", "Finland", "Netherlands", "Finland", "Germany", "United Kingdom", "Netherlands", "United Kingdom", "Ukraine"], "Project_ACR": ["GRAGE"], "Technology_Description": "The EU has to face many challenges in achieving a more balanced regional development and sustainable economic recovery. Many of those challenges have to do with the ageing population trend, urbanization and environment under distress. More liveable and efficient communities is a target to be reached in Europe, where the \u201csilver hair\u201d trends can become a challenging opportunity, from a social, economic and cultural perspective. Despite those challenges are strongly interlinked, solutions provided in urban contexts not often pay due attention to the social process underlying urban trends and to the needs and behaviour of elderly citizens. ", "To": ["2018-11-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Other", "Other", "Higher or Secondary Education Establishments"], "From": ["2014-12-01"], "Project_ID": ["645706"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["UNIVERSITEIT LEIDEN"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["INVESTIGATING EVIDENCE OF HIGH-MASS VARIATIONS OF THE STELLAR INITIAL MASS FUNCTION"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["EHMVSIMF"], "Technology_Description": "One of the most important questions in the study of galaxy evolution is the assumption that stars formed within star clusters with a preferred mass distribution (IMF) independent of time and environment. Major advances in understanding mainly the low-mass IMF variations have been made in the past decade, however, relatively a little attention has been paid to the high-mass IMF. As such some critical questions remain: Does the high-mass IMF vary as a function of time and environment? Is it appropriate to describe the high-mass IMF with a single power-law as we do now? The multi-wavelength datasets that are becoming available now can address these questions. ", "To": ["2019-01-22, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-01-23"], "Project_ID": ["707693"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["SARDEX SRL", "THE UNIVERSITY OF HERTFORDSHIRE HIGHER EDUCATION CORPORATION", "UNIVERSITAT PASSAU", "Fachhochschule Salzburg GmbH"], "EU_Contribution": ["EUR 99 978,75"], "Project_Title": ["Interacting Decentralized Transactional and Ledger Architecture for Mutual Credit"], "Total_Cost": ["EUR 99 978,75"], "Country": ["Italy", "United Kingdom", "Germany", "Austria"], "Project_ACR": ["INTERLACE"], "Technology_Description": "The objective of INTERLACE is to use the Abstract State Interaction Machines framework (CoreASIM) open source output of the FP7 FET project BIOMICS to develop a decentralized transactional and ledger architecture demonstrator for B2B mutual credit. INTERLACE will add to the work already started by its coordinator, Sardex s.r.l., to develop this architecture. SARDEX will use the Open Transaction protocol (OTX) as an intermediate solution between fully centralized and distributed architectures. OTX involves a pool of Auditor nodes to validate the transactions executed by each Notary node. In INTERLACE there will be only one central Notary, as a first step from the current centralized server towards a more distributed architecture. The persistence layer will be implemented as a private blockchain stored on the central server to create a sparse 160-bit address space implemented as a binary hash tree. This approach achieves continuity with the existing solution while also enabling scalability to multiple circuits (multiple Notaries) under the same mathematical and computational framework. SARDEX has been operating successfully an electronic, B2B, zero-interest mutual credit system on the island of Sardinia since 2009. The Sardex system (also known as Circuito di Credito Commerciale) enables local economic actors (SMEs in particular) to trade with each other in a trustful and circular fashion with a unique digital trade credit unit. It does this by monetizing the spare capacity of the local economy in the form of mutual, and taxable, credit between participating companies, at zero interest, on a strong basis of trust, solidarity, and local cultural identity. Therefore, INTERLACE will address very effectively the Workprogramme objective to generate socio-economic impact from EU-funded research. INTERLACE is uniquely positioned to integrate the very advanced results of BIOMICS directly in a deeply innovative, transformative, and successful fintech platform for B2B trade.", "To": ["2018-10-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-04-2016-2017 - FET Innovation Launchpad"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Italy"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["754494"], "Call_for_Proposal": ["H2020-FETOPEN-4-2016-2017"]}, -{"Partners": ["OT BIOELETTRONICA DI BOTTIN ANDREA E MERLO ENRICO & C. S.N.C."], "EU_Contribution": ["EUR 168 277,20"], "Project_Title": ["wireless Body Area Networks for high density MYOelectric neurorehabilitation technologies"], "Total_Cost": ["EUR 168 277,20"], "Country": ["Italy"], "Project_ACR": ["MyoBan"], "Technology_Description": "The next generation of rehabilitation systems will require the evaluation and restoration of the motor impairment using neural information. For this purpose, noninvasive multichannel electromiographic (EMG) technologies are the most promising tools for research and clinical neurorehabilitation applications. Unfortunately, the current systems for high-density (HD) EMG recordings require long cables that impose significant restrictions on the patients and limit free movement. Moreover, the integration of such bulky systems into current rehabilitative exoskeletons may be problematic. For these reasons, the project MyoBan aims to develop an innovative portable HD EMG system based on recent standards designed for the next generation of wireless body area networks. The proposed system will exploit the spatial and temporal characteristics of the surface EMG signals to reduce the data-rate and optimize transmission parameters (e.g. transmitting power, specific absorption rate, real-time processing, etc.). The final aim will be the production of small HD EMG sensors that can be placed on the surface of multiple muscles of the patients with minimal invasiveness and high efficiency. The project will combine expertise in several fields: telecommunication, biomedical signal processing, medical information technologies and neurorehabilitation. The MyoBan is expected to produce substantial progress in the research and clinical applications of neurorehabilitation technologies for motor restoration.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-SE - Society and Enterprise panel"], "Coordinated_in": ["Italy"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-05-01"], "Project_ID": ["753048"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITA DI PISA"], "EU_Contribution": ["EUR 259 558,20"], "Project_Title": ["Innovative high temperature thermal energy storage concept for CSP plants exceeding 50% efficiency"], "Total_Cost": ["EUR 259 558,20"], "Country": ["Italy"], "Project_ACR": ["GLASUNTES"], "Technology_Description": "Energy provision is a big challenge for our Society, being the present production/consumption paradigm not sustainable. To change current trends, a large increase in the share of Renewable Energy Sources (RESs) is crucial. The effectiveness of Thermal Energy Storage (TES) poses Concentrated Solar Power (CSP) systems at the forefront, as the first dispatchable option among all intermittent RESs. In order to realize the CSP potential, the efficiency of the adopted Power Conversion Units (PCUs) must grow over 50%, entailing temperature levels of the order of 1000 \u00b0C: promising solutions are based on Brayton thermodynamic cycles. This project stems from the observation that no existing TES option can be coupled to such PCUs and/or work at these temperatures, and aims at filling this gap. Three interrelated research objectives are proposed, to prove the feasibility and assess the potential of", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["656753"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["INSTITUTO DE MEDICINA MOLECULAR"], "EU_Contribution": ["EUR 160 635,60"], "Project_Title": ["Tracking \u03b3\u03b4 T cell development and TCR\u03b3\u03b4 proximal signalling"], "Total_Cost": ["EUR 160 635,60"], "Country": ["Portugal"], "Project_ACR": ["DevoSignGammaDelta"], "Technology_Description": "T cells are key constituents of our immune system. Two types of T cells are conserved evolutionary and across species: \u03b1\u03b2 and \u03b3\u03b4 T cells. While \u03b1\u03b2 T cells have been intensively studied during the last decades, our knowledge on the development and activation of \u03b3\u03b4 T cells is still limited. Recently, \u03b3\u03b4 T cells have become increasingly attractive for immunotherapy of cancer due to efficient killing of tumour cells independently of major histocompatibility complex (MHC) antigen presentation. The proposed project will elucidate how T cell receptor (TCR) signalling is initiated in \u03b3\u03b4 T cells; and how it contributes to the developmental programming of \u03b3\u03b4 T cell subsets strongly implicated in cancer immunity.", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Portugal"], "Activity": ["Research Organisations"], "From": ["2017-11-01"], "Project_ID": ["752932"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERZITA KOMENSKEHO V BRATISLAVE"], "EU_Contribution": ["EUR 153 381,60"], "Project_Title": ["Towards Highly-Efficient Two-Photon Absorbing Sensitizers within a Confined Chromophore Space:From Computer-Aided Design to New Concepts and Applications"], "Total_Cost": ["EUR 153 381,60"], "Country": ["Slovakia"], "Project_ACR": ["TWOSENS"], "Technology_Description": "Materials exhibiting large two-photon absorption (TPA) are in great demand to meet the needs of emerging laser technologies and applications in medicine and biomedical engineering (bioimaging, photodynamic therapy, microfabrication). Most design strategies to enhance TPA activity rely on construction of extremely large pi-conjugated molecules, which are not appreciated in practice due to difficulties connected with their synthesis or low cell permeability. The fellow recently demonstrated that significant TPA enhancement can be achieved by small perturbations in the heteroaromatic unit, but these effects are often hardly predictable or chemically counter-intuitive.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Slovakia"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["752285"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["INSTITUT CURIE"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["In vivo functions of nuclear envelope rupture and antiviral specialization in dendritic cells"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["DCBIO"], "Technology_Description": "Dendritic cells (DCs) function at the interface between innate and adaptive immunity and have a crucial role in the induction of immune responses. The goal of this project is to uncover the in vivo functions of two novel molecular mechanisms that were recently identified in vitro in DCs. DCs are rapidly activated when DNA is exposed to the cytosol, which can occur in viral infections. Recent work has revealed that DNA is also transiently accessible to the cytosol in migrating DCs due to rupture of the nuclear envelope, and is detected by the cytosolic DNA sensor cGAS. In the first aim of this project we will investigate the immune consequences of nuclear envelope rupture in DCs in vivo. The second aim of this project is to investigate antiviral specialization of DC subsets. Viral infection of DCs impairs their immune functions. Unpublished data has revealed that in humans, the CD141+ DC subset is constitutively resistant to a broad range of enveloped viruses. Resistance was associated with the expression of the GTPase, RAB15. We will investigate the function of RAB15 in DC biology in vivo to study the division of antiviral labor among DC subsets.", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2018-02-01"], "Project_ID": ["751735"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSIDAD DE VALLADOLID"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Biological Valorization of Methane Emissions"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["CH4BioVal"], "Technology_Description": "This action aims to obtain new methanotroph strains able to transform methane into valuable user products, in particular the bio-polymer PHA and ectoine. This will contribute to couple the abatement of a gas with high green-house power, to the production of useful chemicals and bio-consumables, which is in agreement with the objectives of H2020.", "To": ["2019-09-17, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-18"], "Project_ID": ["750126"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE DE BORDEAUX"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Dental anthropology at the Pleistocene-Holocene transition \u2013 insights on lifestyle and funerary behaviour from Neolithic Liguria (Italy)"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["DENPH"], "Technology_Description": "The purpose of the proposed research is using dental anthropology to contribute to our understanding of lifestyle, societies, and belief systems at the Pleistocene-Holocene transition. This is a key moment of our past, during which we shifted from hunting-gathering to the production economy on which we still live. The project will mainly focus a large (150-200 individuals) Neolithic (8-4,000 BP) skeletal assemblage from Liguria (north-western coast of Italy). The research will also involve comparisons with other Neolithic, Mesolithic (10-8,000 BP), and Upper Palaeolithic (30-10,000) sites in Italy and Europe.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["752626"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Smart Optical Metamaterials: A route towards electro-tuneable fast-reversible self-assembly of nanoparticles at controlled electrochemical interfaces"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["S-OMMs"], "Technology_Description": "Futuristic smart optical applications belong to novel artificial materials comprising nanoscale building blocks, exhibiting extra-ordinary optical responses. Recent progress in nanotechnology has enabled developing such optical metamaterials (OMMs) economically via controlled self-assembly of nanoparticles (NPs). Strikingly, a dense nanometre-thick layer of metallic NPs strongly reflects incident light like a \u2018mirror\u2019, whereas a sparse layer enacts a near-transparent \u2018window\u2019. Thus OMMs could form a switchable mirror\u2013window to minimize our energy needs by harvesting light. Besides tuneable-optics, dense OMMs could revolutionise sensing of trace-analytes for detecting threats to our health, safety, and security. I aim to develop new means of dynamic control over resulting NP-layer architecture to make OMMs \u2018smart\u2019, for novel applications like fast-programmable mirrors, -tuneable optical-filters and -cavities. But achieving quick alteration of NP architectures for fast-tuneable optical response is very challenging. Voltage-controlled assembly and disassembly of NPs at interfaces between liquid electrolyte and solid electrodes could be one efficient method. However, these processes are often diffusion-limited, making OMMs slow to respond. This requires the desired systems to be confined, or miniaturized, by developing new schemes and custom-made architectures to ensure assembly/disassembly occurs within sub-second timescales. To achieve this, I will engage novel electrode designs\u2014patterned as rectangular-groove gratings, columnar structures, and flat transparent plates\u2014where NPs can rearrange quickly on desired areas of the electrodes to either reflect or transmit light. This research unites physical-chemistry with optics and nanotechnology. I will develop optimal designs of the systems, via modelling and simulations, and navigate experiments for prototype creation in collaborating laboratories of the Imperial and overseas partners in France, Netherlands, and Germany.", "To": ["2020-06-14, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-06-15"], "Project_ID": ["751763"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF WOLVERHAMPTON"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Impact of Environmental Tobacco Smoke on Incidence and Outcomes of Dementia."], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["DEMETS"], "Technology_Description": "Environmental Tobacco Smoke (ETS) remains prevalent globally. Its association with dementia is unclear. We propose to investigate impacts of ETS on dementia risk and outcomes, and examine levels and determinants of ETS exposure post dementia. In a case-control study in the UK we will recruit 150 elders aged>=75 years with newly diagnosed dementia, 150 with already diagnosed dementia and 150 without dementia from the Royal Wolverhampton hospital. Each participant will be interviewed for socio-demography and risk factors and have saliva samples taken for cotinine analysis. Using multivariate logistic regression models we will examine the association of ETS measured by cotinine with newly diagnosed dementia, and identify factors influencing ETS exposure in people with already diagnosed dementia. We will analyse data from a cohort of 6071 participants aged >=60 years in China, who had the details of ETS exposure recorded in a 5-province health survey in 2007-2009 and were re-interviewed in 2010-2012 to diagnose incident dementia. We will examine incident dementia in relation to baseline ETS exposure, and the impact of ETS exposure on mortality and multimobidity in participants with dementia using multiple adjusted Cox regression models. In the UK we will further run 2 focus groups and explore preventive measures of ETS exposure in older people with and without dementia. Our rich data, including a biomarker elevated upon exposure to ETS will offer internationally applicable insights into the impacts of ETS on dementia incidence and outcomes. Throughout the research project, use of varied study and research methodologies and rigourous training courses, our Fellow will develop his leadership skills and further his career in public health research. The project will strengthen a long-term collaboration between China and EU partners, and will provide Europe with new data to prevent dementia and to reduce ETS.", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["752920"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["HELSINGIN YLIOPISTO"], "EU_Contribution": ["EUR 169 728"], "Project_Title": ["Behaviour, knowledge, policy. The philosophy of science perspective on the applications of the behavioural sciences in policymaking."], "Total_Cost": ["EUR 169 728"], "Country": ["Finland"], "Project_ACR": ["EPISTEMEBEHAVIOUR"], "Technology_Description": "The project addresses the problems emerging from the application of the behavioural sciences to policymaking. These applications refer to research in cognitive psychology, behavioural economics, decision theory and are supposed to provide the knowledge necessary to make policy that is effective. The aim of the project is to analyse how the latest findings in the behavioural sciences are used in policy contexts, to address the challenges which this use provokes, as well as to advance a novel approach to an analysis of behavioural sciences and policy, informed by philosophy of science. ", "To": ["2020-07-15, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-07-16"], "Project_ID": ["751791"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF DUNDEE", "UNIVERSITY OF DUNDEE"], "EU_Contribution": ["EUR 1 687 500"], "Project_Title": ["Mapping Cytokine Signalling Networks using Engineered Surrogate Ligands"], "Total_Cost": ["EUR 1 687 500"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["Cytokine Signalosome"], "Technology_Description": "Cells use an intricate network of intracellular signalling molecules to translate environmental changes, sensed via surface receptors, into cellular responses. Despite their prominent role in regulating every aspect of life, we lack a comprehensive understanding of how signalling networks convey extracellular information into specific bioactivities and fate decisions. To rationally manipulate cell fate, which could fundamentally change the way that we treat human diseases, first we need a systematic understanding of how signalling is initiated and propagated inside the cell. I discovered that specificity of cytokine receptor signalling not only depends on cellular determinants such as receptor density and endocytic trafficking, but can be systematically altered by modulating ligand binding parameters and receptor binding geometries. A fundamentally novel approach combining high-throughput flow cytometry and QMS with engineered cytokine surrogate ligands able to fine-tune signalling responses will generate detailed maps of the signalling networks engaged by cytokines in time and space to unveil the mechanistic basis that allow a receptor to trigger different signal activation programs and bioactivities in response to different ligands. By quantitatively characterizing the signalling programs activated by ligands, using state-of-the-art biochemical, biophysical, structural, genetic and fluorescence imaging techniques, I plan to identify events critical for cellular decisions. By fully characterizing the intracellular signalling network hard-wired inside a cell and understanding its dynamic in response to environmental changes will we be able to comprehend and manipulate the enormous functional plasticity exhibited by cells. TInsights generated will open new fields of investigation where engineered ligands prove indispensable to understand complex biological responses and greatly advance our understanding of cytokine biology and human immunology in health and disease.", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["714680"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["UNIVERSITAIR MEDISCH CENTRUM UTRECHT", "BETH ISRAEL DEACONESS MEDICAL CENTER, INC NON PROFIT CORPORATION"], "EU_Contribution": ["EUR 242 929,80"], "Project_Title": ["The Prelude to Psychosis: Brain network analysis in emerging schizophrenia"], "Total_Cost": ["EUR 242 929,80"], "Country": ["Netherlands", "United States"], "Project_ACR": ["PRE-PSYCH"], "Technology_Description": "Schizophrenia is a severe psychiatric disorder characterized by recurrent psychotic episodes that typically commence in early adulthood. There is consistent evidence for anatomical and functional brain abnormalities in schizophrenia, but their timing is unclear. Changes in behavior and cognition precede the first psychotic episode by many years, suggesting that the underlying neurobiological process predates the onset of psychosis. Clarifying the neurobiology of the pre-onset or \u2018prodromal\u2019 phase will facilitate the development of early intervention and prevention strategies for schizophrenia. I hypothesize that disruptions in the anatomical brain network, and associated disturbances in functional integration among specialized neural circuits, drive changes in behavior and cognition in the prodromal phase. In this project, I have the opportunity to test my hypothesis in a unique sample of medication-naive adolescents and young adults with early signs of impending psychosis, that are followed prospectively as they progress through the vulnerable prodromal period. This sample is collected as part of an ongoing NIMH-funded collaborative research program between a multidisciplinary Harvard/MIT research team and the Shanghai Mental Health Center. Using network science as a mathematical framework, I propose to study brain network architecture in this sample of youths with early signs of impending psychosis, to assess how disruptions in the brain\u2019s network underlie prodromal symptoms and cognition, whether early neuroinflammation contributes to brain network deficits, and to test brain network metrics as early identifiers of emerging psychosis.", "To": ["2020-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2017-04-01"], "Project_ID": ["749201"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Inside Speakers' Corner. Late Medieval Italian Anchoresses in European Context."], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["InSpeCo"], "Technology_Description": "\"Voluntary reclusion was an ancient form of penitential religious life based on withdrawing into a tight space, either temporarily or forever. The particular phenomenon of urban reclusion which flourished in the 13th and 14th centuries was a mainly female activity, need not be tied to a religious order, and seems to have been linked to the expansion of cities across Europe. It is an important indicator of female levels of religious participation and of their social role since these women often acted as consultants and advisors to the wider community. This research project will thus improve our understanding of a phenomenon that characterized all of Latin Europe, as of the condition of medieval woman, while also reshaping our image of the medieval city, to one scattered with cells. There is, currently, a great disparity in historiographical terms between Italy and the rest of the continent on this subject. Whereas some parts of Europe and of northern Italy are relatively well researched, others are devoid of studies. The aim of this project is thus to verify whether \u2013 and if so, how and why \u2013 there was an Italian model of reclusion with characteristics different to those beyond the Alps; how recluses related to the urban communities from which they withdrew and the extent to which this phenomenon was a way for medieval women to break the silence imposed by St Paul (\"Women are to be silent in the churches. They are not permitted to speak\", 1 Corinthians 14:34); to exercise from and thanks to the cell a sort of power on the civil and ecclesiastical society; to break out of conventional, restricted roles of mother or wife or nun imposed by the medieval society, or more often a dignified way of life for poor single women, for whom the lack of a dowry barred entry to a nunnery or marriage. The first step will thus be the construction of a prosopographical database of Italian anchoresses mapping the phenomenon, followed by a comparative study of Italy in European context\"", "To": ["2019-09-10, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-11"], "Project_ID": ["751526"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["QUEEN MARY UNIVERSITY OF LONDON"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Amplitudes and form factors via integrability"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["AFFINITY"], "Technology_Description": "Our theoretical description of natural phenomena is mostly limited to the regime where the interaction among fundamental particles is sufficiently weak, making the understanding of strongly-coupled gauge theories one of the main challenges of current research in theoretical physics. This proposal aims to study the structure of form factors -- important off-shell generalizations of scattering amplitudes of great phenomenological relevance -- in the maximally supersymmetric Yang-Mills theory at all values of the coupling. Importantly, the strong- and finite-coupling regimes are made accessible by the AdS/CFT correspondence and its integrable structure, respectively. The methods required to achieve the goals of this proposal will extend in a non-trivial way the recent beautiful results in the related field of scattering amplitudes. In particular we plan to derive a precise correspondence between form factors and Wilson loops, to exploit this picture to investigate the strong-coupling regime, and to extract finite-coupling predictions for form factors in the spirit of the recent, powerful OPE approach to scattering amplitudes. Finally we will also analyze the properties of form factors under collinear factorization. ", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["749909"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITETET I BERGEN"], "EU_Contribution": ["EUR 196 400,40"], "Project_Title": ["The Symbolism of the Body in Northern Europe. Cognitive Metaphors and Old Norse Myth from the Viking Age to Late Medieval Times"], "Total_Cost": ["EUR 196 400,40"], "Country": ["Norway"], "Project_ACR": ["SYMBODIN"], "Technology_Description": "The aim of the proposed research is to investigate the integrative function of bodily metaphors within the Old Norse Literature and Culture. The research will span the culturally important transition from pre-Christian culture to the products of Christian literacy. Its starting point will be the mythic narratives connected with initiation and sacrifice, which have a foremost position in the pre-Christian religion and which are especially rich in the cognitive metaphors of the human body. These myths and rituals exerted an influence as a pattern or model for the whole society, and provide thus an excellent tool for the understanding of its symbolic system and values. In the next step of the project the transition towards Christianity will be explored and assessed, especially its reevaluation of cognitive metaphors of the body, with the aim to map the transformations of symbolism on the borders of two cultural and religious systems. This endeavour will provide a completely new theory shedding new light on the production of meaning in culture and its reinterpretations. The research itself is to be naturally interdisciplinary, integrating religious studies, philology, cognitive linguistics, anthropology and folkloristics. My previous research prepared me for this task to a certain degree, but knowledge exchange is needed to bring it to a completion, especially consultations with scholars and experts in the field of Old Norse Studies. All this can be achieved by a 18 months research internship at the University in Bergen, which provides the best academic conditions for this project, supervised by prof. Jens Eike Schnall, and by a 6 month secondment in Reykjav\u00edk, at the University of Iceland and at the \u00c1rni Magn\u00fasson Institute for Icelandic Studies. This project will apply innovative interdisciplinary approach to the topic and initiate a collaboration between Prague and Bergen and Prague and Reykjav\u00edk researchers in Old Norse religion.", "To": ["2020-07-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Norway"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-08-01"], "Project_ID": ["750379"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSIDAD POLITECNICA DE CARTAGENA"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["INvestigating SDN Programmability ImpRovING optical South- and North- bound Interfaces"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["INSPIRING-SNI"], "Technology_Description": "Population needs for Internet connectivity rely on carrier networks currently challenged by the ever-increasing network complexity, traffic volume, and dynamicity. Software Defined Networking (SDN) has entered the networking scene as an enabling technology that brings programmability to the network by decoupling the forwarding data-plane actions from the logic control-plane decisions through application programming interfaces. However, the variety of controllers governing different network segments and interfaces for control and management endangers actual carrier-grade SDN deployments.", "To": ["2020-02-29, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["750611"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSIDADE DO ALGARVE"], "EU_Contribution": ["EUR 148 635,60"], "Project_Title": ["Optimisation of Tidal energy Converter Arrays"], "Total_Cost": ["EUR 148 635,60"], "Country": ["Portugal"], "Project_ACR": ["OpTiCA"], "Technology_Description": "As technology readiness level of Tidal Energy Converters (TECs) increases, moving from prototype demonstration to commercialisation, research efforts are focusing on TEC arrays layout optimisation to reduce costs and become competitive in comparison with other energy systems. Even though there are several prototypes of different scales that have been tested on the last years (mostly under controlled conditions) there is limited data on deployments in real conditions which negatively affects the accurate formulation of constrained problems on array schemes resulting on incomplete layout optimisation models. This project aims to provide a significant contribution towards the understanding of (a) the effects of TECs interactions with the environment; (b) the capabilities and limitations of common strategies used for the numerical modelling of TECs; and (c) how to mathematically formulate optimisation models to solve the TEC array layout problem considering technical, socio-economic and environmental constraints. From the methodology point of view, constraint optimisation models will be mathematically formulated considering ocean energy protocols, data collected from in-field measurements of prototypes tested in real environments and with surrogates built from validated numerical simulations. The outcomes of the project will contribute to improve common guidelines and standards for licensing tidal energy projects and de-risk financial investment. The Experienced Researcher (ER) will emerge from the project with an in-depth knowledge of tidal stream energy, training in mathematical optimisation and on new skills in data collection, increased competence on numerical modelling, and strong skills in research project management and coordination. This will grant him the capacity of achieving maturity as a researcher on ocean energy, a new emerging sector with great growth potential.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Portugal"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["748747"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI TERAMO"], "EU_Contribution": ["EUR 180 277,20"], "Project_Title": ["Exploring dry storage as an alternative biobanking strategy inspired by Nature"], "Total_Cost": ["EUR 180 277,20"], "Country": ["Italy"], "Project_ACR": ["DRYSTORE"], "Technology_Description": "Biobanking under liquid nitrogen (LN) has satisfactory efficiency but it comes with many drawbacks (e.g. expensive, high carbon footprint, need dedicated facilities, trained personnel, and continuous monitoring and LN supply). Searching Nature for alternatives, long-term preservation there is done by drying rather than freezing. To date, however, mammalian cells do not survive the drying process. Even so, if somatic cells genetic and epigenetic load is maintained, drying can find an important role in biobanking, a fast growing global industry. We aim to elucidate the effects of drying on DNA structure and function, crucial aspects of long-term biobanking not investigated yet, using fibroblast as a model cell, and combining advanced freezing and drying techniques with state-of-the-art Somatic Cell Nuclear Transfer (SCNT) and latest genomic technologies. The expected outcomes are definitive data on effects of drying on genomic stability/function, and possible discovery of a protocol to protect the epi/genetic load during cell drying. The crossing between the Researcher\u2019s scientific interest and experience in sperm biology, andrology, cryobiology and drying and the Supervisor\u2019s expertise in embryology and SCNT creates an attractive and very solid background for this proposal, with mutual benefit to both Host and Researcher. While strengthening the Supervisor\u2019s laboratory with his expertise, the Researcher will enhance his creative potential and further develop his interdisciplinary and communication skills by learning SCNT and whole genome analysis as well as mentoring students, participating in conferences, and communicating research results to targeted audiences (scientists, general public, students, stakeholders, policymakers), thus enhancing his scientific profile. This proposal is the perfect stepping stone for the Researcher to become an independent scientist and an expert in desiccation for biobanking, while contributing a competitive advantage to the Host.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["749537"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF EAST ANGLIA"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Volcanoes: eruptive style, pre-eruptive evolution and risk"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["VESPER"], "Technology_Description": "This project will use the compositions and crystal cargoes of erupted magmas to study pre-eruptive behaviour of magmatic systems. The aim is to understand their relationship to, and control on, periodicity and style of volcanic eruptions to mitigate hazards and risks. To do this we will undertake detailed description of the whole-rock composition and mineral chemistry of volcanic rocks from active intra-plate and subduction-related volcanoes. New knowledge about zircon behaviour will then be considered in the context of these well-constrained systems.", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["749611"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ROYAL COLLEGE OF SURGEONS IN IRELAND"], "EU_Contribution": ["EUR 187 866"], "Project_Title": ["Platelet tractions through the Glycoprotein (GP) GPIb receptor as a potential marker for platelet reactivity"], "Total_Cost": ["EUR 187 866"], "Country": ["Ireland"], "Project_ACR": ["ThromboForce"], "Technology_Description": "Platelet-mediated thrombosis is a major cause of death and disability globally. Thrombosis occurs when platelets adhere and aggregate. In the arterial circulation initial platelet adhesion occurs when the platelet glycoprotein (GP) I-IX-V receptor binds to von Willebrand Factor (vWF). Increased or decreased expression levels of GPIb are associated with increased risk for cardiovascular events and bleeding respectively. The expression of GPIb varies significantly among healthy subjects. The proposed project aims to characterise the role of GPIb expression levels on traction forces and platelet reactivity. It therefore combines my significant expertise in cellular mechanobiology and traction force microscopy with theclinical expertise of Prof Dermot Kenny\u2019s group in platelet biology and the development of diagnostic assays for platelet function. A micropost array platform for high throughput, single cell, traction force measurements will be developed and applied to understand the interaction between GPIb traction forces andplatelet reactivity, first in healthy donors and then in patients with cardiovascular disease receiving antiplatelet therapy. This platform could in the future be further exploited for examining platelet function to further understand platelet cancer interactions, and for the innovation of refined diagnostics to assess platelet reactivity in individual patients.", "To": ["2019-06-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-15"], "Project_ID": ["747586"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FUNDACION PUBLICA ANDALUZA PARA LA INVESTIGACION DE MALAGA EN BIOMEDICINA Y SALUD"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Targeting the Endocannabinoid System within Islets of Langerhans to Protect against Immune Destruction."], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["DIRECtA"], "Technology_Description": "Europe has the highest prevalence per capita of children with type 1 diabetes (T1D), an autoimmune disease with no cure that results in progressive destruction, and finally an absolute loss, of insulin-producing beta (\u03b2) cells in islets of Langerhans in the pancreas. This means that patients require exogenous insulin administration for life. Additionally, prolonged uncontrolled blood glucose levels increase the risk of cardiovascular diseases, peripheral neuropathy, renal failure and numerous infections. The endocannabinoid receptors (ECRs) CB1, CB2 and GPR55 are regulators of metabolism and immune action and are also present on \u03b2 cells. Cannabidiol, a CB1 antagonist, reduced the incidence of T1D in mice by reducing insulitis, thereby preserving \u03b2 cell mass. Additionally, blockade of CB1 alters insulin secretion, increasing proliferation and autophagy in \u03b2 cells. Importantly, \u03b2 cell-specific CB1 knockout mice have no T-cell infiltration in islets when their pancreas is challenged. Furthermore, activation of GPR55 and CB2 are reported to be beneficial in protecting from inflammation. In this project we intend to study the interaction of the ECRs and their potential synergy for protecting \u03b2 cells from insulitis. For this purpose, we will generate a non-obese diabetic (spontaneously develops autoimmune insulitis) \u03b2 cell-specific CB1 knockout mouse, and use pharmacological approaches to enhance GPR55 and CB2 signalling to determine if the diabetic condition can be prevented/ameliorated. We will assess \u03b2 cell damage together with mitochondrial function, autophagy, and inflammatory responses in our mouse model and after pharmacological manipulation. Thus, this project proposes a new strategy, not focusing on the immune system but on the role that \u03b2 cells themselves play in modulating their own reactivity, for the development of new therapies for preventing and/or treating T1D.", "To": ["2020-01-02, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2018-01-03"], "Project_ID": ["748749"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["LEIBNIZ-INSTITUT FUER FESTKOERPER- UND WERKSTOFFFORSCHUNG DRESDEN E.V."], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Theoretical insides in endohedral metallofullerene based Self-Assembled Monolayers: Statics and Dynamics."], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["SamSD"], "Technology_Description": "Modeling of formation and properties self-assembled monolayer (SAM) is a very challenging task, especially if highly functional-ligands are concerned. It is true, for instance, in the case of endohedral metallofullerene (EMF) based SAM - a promising single molecular magnet (SMM) grids in-making. Properties of such SMM grids would be a function of SAM architecture (attachment types and crowding effects) and inner-cluster dynamics under these geometrical constrains. Electronic structure complexity of EMFs and structural mobility of ligands in SAMs brings a dual issue. On the one hand, a minimal level of theory to address the magnetic properties of the systems would require \u201ccomplete active space\u201d-quality methods, yet the whole size (~10E3 atoms) of the system makes these computations hardly feasible and is limited so far to single molecules. On the other hand, while the system dynamic can be approached by less computationally demanding semiclassical or even classical approaches, such methods are unable to give a reliable magneto-physics of the SMM unit. This project will offer a solution to this problem by extensive development of the multiscale methods (MSM), in which the whole system is divided into the regions described with different levels of theory accordingly to its complexity. Developed protocols and schemes would be universals across SAM field and highly profitable for the SMM industry on a whole.", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations"], "From": ["2017-11-01"], "Project_ID": ["748635"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY COLLEGE LONDON"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Revisiting an ancient craft in a contested region: The analytical paradigm of prehistoric pottery from Cyprus"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ReCyPot"], "Technology_Description": "ReCyPot is a large-scale, interdisciplinary study of ancient ceramics from the region of Lapithos on the northern coast of Cyprus that addresses four different themes of cross-cultural and cross-regional significance: 1) ancient technology, 2) ancient Mediterranean history and archaeology, 3) the restudy of older excavated material with new methods of analysis and interpretation and 4) the study of ancient artefacts from areas presently inaccessible to archaeological and historical research. Integrating ceramic petrography and methods of chemical and microstructural analysis (including WD-XRF, NAA and SEM), this will be a thorough analytical study of ancient pottery, dated to the end of the third millennium and the second millennium BC, the comparative analysis of contemporary pottery from the region, as well as ceramics from intervening periods in Lapithos. While the project deals with a specific region on the island of Cyprus, it can be used as an exemplar for addressing broader, cross-cultural and methodological questions regarding the definition and recording of pottery traditions, how these are transformed and how modern archaeologists can perceive and study them. The project will attempt to reconstruct the ancient pottery traditions of Lapithos and define those compositional and technological elements that form the Lapithos ceramic profile. Beyond the definition of regional ceramic traditions and elements of stability and change through time, this project will consider environmental, technological, sociocultural and historical factors that must have had an impact on ceramic production, distribution and consumption. Pottery production will be integrated into its regional and inter-regional socio-economic context, and provide an insight into the ancient society and history of the region, an integral part of the ancient Mediterranean.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["747339"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAET STUTTGART"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Direct cooling of dipolar molecules"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["coolDips"], "Technology_Description": "Full quantum control of molecules has been an outstanding goal for decades. Cooling molecules provides a most promising answer to address this challenge. With recent progress in experimental quantum physics, such cooling is finally within reach. The aim of this project is to demonstrate the novel technique of molecular laser cooling for a gas of barium monofluoride molecules. Realizing a cold gas of these dipolar molecules will pave the way for a large number of novel and interdisciplinary applications ranging from few- and many-body physics to cold chemistry and tests of fundamental symmetries. The combination of this unique research project with the excellent environment for training, networking and research at the University of Stuttgart will ideally prepare the applicant, Dr. Tim Langen, for a future career as an independent research group leader.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["746525"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Activity-dependent modulation of synapse identity"], "Total_Cost": ["EUR 2 000 000"], "Country": ["France", "France"], "Project_ACR": ["SynID"], "Technology_Description": "The mature brain results from the formation of precise networks between functionally and morphologically distinct types of neurons. A given neuron forms synapses with a limited number of partners and on precise subcellular localizations. Understanding what controls this specificity is mandatory not only to understand brain functions but also the aetiology of synaptopathies such as autism spectrum disorders or schizophrenia. Various molecules define the identity of each type of synapse. Furthermore, neuronal activity-dependent mechanisms sculpt and stabilize neuronal connectivity. I posit that neuronal activity controls the molecular identity of synapses and that this regulation occurs through mechanisms specific for each neuronal population, thereby regulating synapse specificity. I focus on the olivocerebellar network, which is involved in motor control and also in cognitive processes. In this well-characterized circuit, two different excitatory inputs, the climbing fibres and the parallel fibres converge on the same target, the cerebellar Purkinje cells, compete for their non-overlapping territory and possess distinct functional, morphological and molecular characteristics. Purkinje cells thus provide an ideal model to study the molecular basis of synapse identity and its regulation. In the past years, I have developed new genetic tools to dissect the molecular characteristics of the olivocerebellar network at the neuron- and synapse\u2013specific levels. I propose to generate new mouse models to control neuronal activity, in vivo and during development, specifically in the two Purkinje cell excitatory afferents. Combining these tools, my objectives are to describe the molecular diversity of synapses, show its control by neuronal activity, and characterize the molecular determinants of synapse identity. This study will bring a unifying view of the mechanisms controlling the development of a functional brain.", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-10-01"], "Project_ID": ["724601"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Deciphering the role of oxylipins in the epigenetic mechanisms controlling plant immunization."], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["EPILIPIN"], "Technology_Description": "Reducing crop losses caused by pests and diseases is absolutely necessary to feed the increasing world population, but the use of pesticides increases the damage to the environment and contributes to climate change. As a result, international entities such as the European Union are promoting the search for alternative strategies. Experts point to \u201cplant immunization\u201d or priming, as the safest and most effective approach to boost the endogenous plant immune system. Unfortunately, deeper knowledge of the involved mechanisms is needed for its application in crop protection. In this context, epigenetic mechanisms and oxylipin pathways are involved in priming processes but their specific contribution as well as the relationship between these two pathways has not yet been addressed. In order to fill this gap in our knowledge we propose an ambitious but feasible project that builds on solid and exciting preliminary results. We will use the unique genetic and molecular tools available in the model plant Arabidopsis thaliana to analyse first the role of oxylipin natural compounds in different priming processes and then, study the relationship between both molecular pathways to delineate plant defence mechanisms and priming. The synergistic interaction formed by the host group, world-leading in oxylipins research, and the applicant, an expert in epigenetics, guarantees the maximization of two way transfer of knowledge, training and networking possibilities. Moreover, this action has a potentially remarkable impact and represents a key point in the applicant\u00b4s career complementing her current knowledge and expanding her skills. Taking these considerations together, the EPILIPIN project offers a unique opportunity for the development of a research that perfectly fits the EU concerns and priorities of improving crop yields minimizing the impact of agriculture on the environment by exploring the use of natural compounds (oxylipins) to trigger long term immunization (priming).", "To": ["2020-01-15, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2018-01-16"], "Project_ID": ["746136"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["New DELLA-based biotechnological tools for sustainable Agriculture"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["DELLATECH"], "Technology_Description": "Since their discovery, the plant hormones gibberellins (GAs) and their inhibitors have become a widely used tool to improve very diverse agronomical aspects, such as the size and productivity of grasses, horticultural species and ornamental plants. However, indiscriminate application of these compounds also provokes undesired secondary effects. For instance, GA application is used in agriculture to promote and synchronize fruit development, but it weakens the defense mechanisms against pests. Therefore, there is a serious need to find new GA-related biotechnological tools that specifically improve certain agronomical traits without the lateral effects. Based on the deep knowledge generated about GA signaling in the past 20 years with the help of our own lab, here we propose to (1) establish a method to generate plant varieties that specifically improve certain GA-related traits without the lateral effects; (2) search for compounds that specifically mimic certain aspects of GA signaling; and (3) in conjunction with a Spanish biotech company, provide a well-trained academic scientist with the capacities needed to develop a professional career within industry-oriented biotechnological research.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-04-01"], "Project_ID": ["746396"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE D'AIX MARSEILLE"], "EU_Contribution": ["EUR 108 172,50"], "Project_Title": ["Systematic analysis of Pacific phytoplankton and islands regional effects"], "Total_Cost": ["EUR 108 172,50"], "Country": ["France"], "Project_ACR": ["SAPPHIRE"], "Technology_Description": "\"Phytoplankton, the tiny algae that fix carbon dioxide via photosynthesis, represent the base of the oceanic food chain and support essentially all life in the oceans. In the tropical Pacific, where phytoplankton biomass is low, local nutrient enrichments near islands support ecosystems characterized by higher biomass and biodiversity. While this \"island effect\" has been known for 60 years, the vast majority of islands remain unstudied and impacts at the basin scale are unknown. Additionally, little is known regarding changes in phytoplankton community structure despite implications for higher trophic levels. The SAPPHIRE project will elucidate the impact of islands on phytoplankton by conducting the first systematic study of the island effect in the tropical Pacific from a suite of physical and biological satellite data. This project leverages the OUTPACE in situ 20\u00b0S transect that sampled phytoplankton community composition nearby several islands in 2015 and the breakthrough satellite-based PHYSAT method that detects phytoplankton functional groups from space. Novel methods identifying and characterizing the island effect will be first developed in the OUTPACE region from in situ and satellite data, then applied to the entire tropical Pacific using satellite data. The ultimate goals are to 1) quantify the impact of islands on phytoplankton and physics in the tropical Pacific and 2) classify the islands as a function of enrichment processes and phytoplankton responses using cutting-edge machine learning techniques. SAPPHIRE provides a highly original perspective on marine ecological research by systematically conducting thousands of small-scale process studies over a large area, effectively providing a large-scale assessment of a mesoscale process. This project will be an important step in my career development by establishing me as a leading scientist in the emerging field of multidisciplinary data-intensive oceanography in Europe.\"", "To": ["2019-05-23, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-02-24"], "Project_ID": ["746530"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF LIVERPOOL", "THE UNIVERSITY OF LIVERPOOL"], "EU_Contribution": ["EUR 1 668 418"], "Project_Title": ["Beyond the Iron Curtain"], "Total_Cost": ["EUR 1 668 418"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["BYONIC"], "Technology_Description": "As one of the largest carbon reservoirs in the Earth system, the ocean is central to understanding past, present and future fluctuations in atmospheric carbon dioxide. In this context, microscopic plants called phytoplankton are key as they consume carbon dioxide during photosynthesis and transfer part of this carbon to the ocean\u2019s interior and ultimately the lithosphere. The overall abundance of phytoplankton also forms the foundation of ocean food webs and drives the richness of marine fisheries.", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["724289"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["UNIVERSITE DE GENEVE"], "EU_Contribution": ["EUR 265 840,20"], "Project_Title": ["Quantum Kinetic Equations for Pre-thermal Light and Matter"], "Total_Cost": ["EUR 265 840,20"], "Country": ["Switzerland"], "Project_ACR": ["QUAKE4PRELIMAT"], "Technology_Description": "One of the research forefronts in quantum many body physics, is represented by the non-equilibrium dynamics of strongly", "To": ["2021-02-27, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-02-28"], "Project_ID": ["745608"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITEIT UTRECHT", "UNIVERSITEIT UTRECHT"], "EU_Contribution": ["EUR 1 499 902,50"], "Project_Title": ["Dynamic Urban Environmental Exposures on Depression and Suicide"], "Total_Cost": ["EUR 1 499 902,50"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["NEEDS"], "Technology_Description": "19% of the Dutch population suffer from depression and people affected by depression have a significantly higher suicide risk. Although the World Health Organization attributes modifiable environmental factors including urban environments (i.e. the built, natural and social environments) to health outcomes, they are largely disregarded as either stressors or buffers in scientific debates on depression and suicide. A limitation of current studies is that urban environmental features are often restricted to the neighbourhoods within which people live. This may result in incorrect conclusions about health-influencing factors and inappropriate policies. Human life ultimately unfolds over space-time; people are exposed to multiple urban environments not only during daily life but also over the course of their lives. It is this, not yet assessed spatiotemporal interplay of urban exposures that might revolutionize health assessments.", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["714993"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["New photoswitchable materials based on electron transfer process"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["ETSMM"], "Technology_Description": "Design and synthesis of molecular materials whose physical properties can be controlled by external stimuli are of the most advanced research interests. In this project we aim to synthesize and study in-depth a family of molecular compounds with adjustable electronic properties based on an intramolecular electron transfer (ET) mechanism. The ET phenomenon defines two stable states that can be controlled by temperature, light, electric field, pressure or a chemical stimulus and can be used to design new molecular switches.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2017-04-01"], "Project_ID": ["745696"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ISRAEL NATIONAL MUSEUM OF SCIENCE, TECHNOLOGY AND SPACE DANIEL AND MATILDE RECANATI CENTER", "MIGAL GALILEE RESEARCH INSTITUTE LTD", "WEIZMANN INSTITUTE OF SCIENCE", "Bloomfield Science Museum Jerusalem (BSMJ)", "THE HEBREW UNIVERSITY OF JERUSALEM", "TEL AVIV UNIVERSITY", "SAMI SHAMOON COLLEGE OF ENGINEERING(R.A.) FRIENDLY SOCIETY", "UNIVERSITY OF HAIFA", "THE OPEN UNIVERSITY*", "BAR ILAN UNIVERSITY", "ISRAEL OCEANOGRAPHIC AND LIMNOLOGICAL RESEARCH LIMITED", "ORANIM ACADEMIC COLLEGE OF EDUCATION - THE KIBBUTZ MOVEMENT", "AL-QASEMI ACADEMY ASSOCIATION", "INTERDISCIPLINARY CENTER (IDC) HERZLIYA"], "EU_Contribution": ["EUR 300 000"], "Project_Title": ["Reaserchers' Night Project 2016-2017 in Israel"], "Total_Cost": ["EUR 870 025"], "Country": ["Israel", "Israel", "Israel", "Israel", "Israel", "Israel", "Israel", "Israel", "Israel", "Israel", "Israel", "Israel", "Israel", "Israel"], "Project_ACR": ["ERNI2016"], "Technology_Description": "Following previous TEN years of successful implementation of European Researchers' Night in Israel we will have:", "To": ["2018-01-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-NIGHT-2016 - European Researchers' Night"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Israel"], "Activity": ["Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Other", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["721875"], "Call_for_Proposal": ["H2020-MSCA-NIGHT-2016"]}, -{"Partners": ["UNIVERSITEIT LEIDEN", "NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU", "TECHNISCHE UNIVERSITEIT DELFT", "INSTITUT POLYTECHNIQUE DE GRENOBLE", "CRANFIELD UNIVERSITY", "ASTON UNIVERSITY", "LINKOPINGS UNIVERSITET"], "EU_Contribution": ["EUR 3 995 643,24"], "Project_Title": ["Circular European Economy Innovative Training Network"], "Total_Cost": ["EUR 3 995 643,24"], "Country": ["Netherlands", "Norway", "Netherlands", "France", "United Kingdom", "United Kingdom", "Sweden"], "Project_ACR": ["CircEuit"], "Technology_Description": "Circ\u20acuit \u2013 the Circular European Economy Innovative Training Network - creates a cohort of future leaders in research, policy & business through its innovative training programme focused on the Circular Economy. Circular business models, based on leasing or providing functionality rather than products, often called Product Services Systems, are widely seen as a way how business can create sustainable jobs and growth. The Ellen MacArthur Foundation (EMF) and McKinsey calculated that circular business will create billions of value. This opportunity has become an important development area for researchers engaged in the sustainability, engineering and design and business fields. ", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2016 - Innovative Training Networks"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["721909"], "Call_for_Proposal": ["H2020-MSCA-ITN-2016"]}, -{"Partners": ["NATURAL HISTORY MUSEUM"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["GOethite in Supergene Systems: ANalysing trace element substitution goethite and related iron oxides and oxyhydroxides."], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["GOSSAN"], "Technology_Description": "The GOSSAN project will provide a full and accurate study on the geochemical, morphological and structural composition of iron oxides and oxyhydroxide compounds, The attention will be focalized on goethite in different types of Supergene Ore deposits (SOD). More precisely, it is aimed to investigate the concentration, structural position and cationic exchange and economic potential of goethite as an unconventional source of \u201cCritical Elements\u201d (CE).", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2017-10-01"], "Project_ID": ["751103"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITEIT LEIDEN", "UNIVERSITEIT LEIDEN"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Understanding and Controlling Glycosylation Reactions"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["GLYCONTROL"], "Technology_Description": "This proposal aims to understand and control glycosylation reactions. In a glycosylation reaction a \u201cdonor\u201d glycoside and an \u201cacceptor\u201d (the nucleophile) are united to form an oligosaccharide. Although it is the central reaction in carbohydrate chemistry, our understanding of this reaction, in terms of stereoselectivity and productivity is still limited. The structural variation in the building blocks leads to a complex continuum of SN2-SN1 mechanisms that operates and it is currently impossible to predict where in the continuum the reaction exactly takes place. This proposal provides fundamental insight into the outcome of glycosylations by studying both the activated donor glycoside and the acceptor nucleophile. Activation of a donor glycoside leads to different reactive intermediates, covalent anomeric species (most often triflates) and oxocarbenium ion-like species. The relative reactivity of these species is quantified to generate novel reactivity charts. The covalent species are studied by innovative competition experiments, kinetic studies and NMR spectroscopy. The (fleeting) oxocarbenium ion-like intermediates are probed by a computational approach and by \u201csuper-acid NMR\u201d studies in which stable glycosyl cations are generated and studied in super-acid media. The reactivity of glycosyl acceptors is systematically studied in a set of SN2 or SN1-type glycosylations. Using kinetic studies and competition reactions charts of acceptor nucleophilicity are compiled. The reactivity of the donors and acceptors is matched using a family of tailor made \u201creactivity modulators\u201d, spanning a broad reactivity window bridging the reactivity gap between the building blocks leading to predictable glycosylations. The developed methodology is employed in automated solid phase syntheses of libraries of oligosaccharides featuring multiple cis-glycosidic linkages. The proposal is a major step forward in the development of a general glycosylation procedure.", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["726072"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE"], "EU_Contribution": ["EUR 187 419,60"], "Project_Title": ["Nanoscale Earth Abundant Catalysts for Hydrosilylation of Alkenes and Industrial applications"], "Total_Cost": ["EUR 187 419,60"], "Country": ["Switzerland"], "Project_ACR": ["NEACHA"], "Technology_Description": "The hydrosilylation of alkenes represents one of the largest applications of homogeneous catalysis on an industrial scale, and currently platinum-based catalysts are used in the industries which are expensive. Although homogeneous Earth abundant metal catalysts have been developed, they are not suitable for large-scale industrial applications. Hence, I will develop novel, inexpensive, and Earth-Abundant supported base metal nano-catalysts for the hydrosilylation of alkenes to produce linear alkylsilanes including Si-polymers, which are important products in the chemicals, materials, and pharmaceutical industries. The proposed catalysts are heterogeneous, easily separable from the reaction mixture, and reusable. To achieve this aim, supported Fe, Co, Ni and Mn nano-catalysts will be prepared, characterized, and tested for catalysis. Priority will be given to iron-based catalysts. The most effective nano-catalysts will be applied to the production of silicon-polymers/materials. Altogether, the acquired knowledge from this research project will help the scientific and chemical community to design cheap nano-catalysts for hydrosilylation. This project will be carried out in Laboratory of Inorganic Synthesis and Catalysis (LSCI) at EPFL under the supervision of Prof. Xile Hu. This project will allow me to develop my knowledge and skills in the field of nanomaterials and heterogeneous catalysis in order to enhance my future as an independent researcher in the area of catalysis for advanced organic synthesis and energy applications.", "To": ["2019-06-30, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Switzerland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["745083"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 200 194,80"], "Project_Title": ["Specialised plant cell types via developmentally-controlled gene knockouts: a key step towards fully customised plants"], "Total_Cost": ["EUR 200 194,80"], "Country": ["Denmark"], "Project_ACR": ["GREEN-SPECIALISTS"], "Technology_Description": "A goal of plant engineering is to produce valuable resources from CO2 and solar energy while exploiting the natural advantages of plants as production platforms. Plants have highly specialised cell types and sophisticated development programs, resulting in specialist producer cells that are supported by non-producer parts. Plants are the only organisms that combine autotrophy and extensive multicellular differentiation, yet current engineering strategies fail to fully exploit the potential advantages of plants as chemical production systems. This action proposes to develop and demonstrate a crucial technical advance in plant engineering: developmentally-programmed gene knock-outs in specialised cell types.", "To": ["2020-02-29, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["752430"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 212 194,80"], "Project_Title": ["Molecular understanding of metabolic complexes: Towards engineering the next generation of synthetic biosystems"], "Total_Cost": ["EUR 212 194,80"], "Country": ["Denmark"], "Project_ACR": ["METABOLON"], "Technology_Description": "Why most plant natural products escape industrial production? So far, synthesis of many of these high-value compounds in microbes is simply based on putting together all the players in a pathway. Nevertheless, to produce its stunning chemical diversity, nature uses much more elaborate biosynthetic networks, frequently involving the formation of macromolecular assemblies termed metabolons. These complexes utilize dynamic interactions and partner exchange to produce the desired compounds in a coordinated fashion. To take my biotechnological expertise one step further, I will study the dynamic mechanisms that rule the assembly and regulation of metabolons and use this knowledge to reshape the way microbial production platforms are engineered.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["752619"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 200 194,80"], "Project_Title": ["Sounds Delicious: A historical anthropology of listening and sound in Danish and French cooking"], "Total_Cost": ["EUR 200 194,80"], "Country": ["Denmark"], "Project_ACR": ["Sounds Delicious"], "Technology_Description": "The Sounds Delicious project investigates how sound and listening function in different culinary traditions in Denmark and France. The project aims to construct a new interdisciplinary dialogue between Sound Studies and Food Studies that will enrich how we study everyday cooking processes and the gustatory. This study questions how we construct cultural histories of cooking. I suggest that dominant research paradigms based on alphanumeric and visual epistemic practices (words, images, measurements) are insufficient for fully understanding the particular components and choreography of a cook\u2019s practice\u2014and what cooking relates about personal histories and larger social and cultural tendencies. In adopting an aural perspective of the kitchen, I engage alternative methods of perceiving evidence, and I revisit approaches of documentation, analysis and communication of the everyday. In this project sound and sonic practices are both research object and research method\u2014both matter and medium. Sound is used to trace, analyse, even reenact different performances of cooking. I will establish a new corpus of examples documenting sound and aural perception in Danish and French kitchens between the 19th and 21st centuries. In working with a varied set of historical and anthropological tools, I will not only identify sounds in cooking, but introduce performances of cooking in relation to other histories of sonic and sensory knowing.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["753565"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE PARIS-SUD", "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS", "UNIVERSITAET REGENSBURG", "FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS", "UNIVERSITA DI PISA", "CONSIGLIO NAZIONALE DELLE RICERCHE", "UNIVERSITY OF LEEDS", "TEMATYS"], "EU_Contribution": ["EUR 3 786 160"], "Project_Title": ["Mid- and far-IR optoelectronic devices based on Bose-Einstein condensation"], "Total_Cost": ["EUR 3 786 160"], "Country": ["France", "France", "Germany", "Greece", "Italy", "Italy", "United Kingdom", "France"], "Project_ACR": ["MIR-BOSE"], "Technology_Description": "Optoelectronic devices typically operate in the weak coupling regime between light and matter, for example in conventional lasers relying on population inversion to achieve optical gain. Recently there has been a surge of interest in quantum systems operating instead in the strong coupling regime, when the coupling strength of the light-matter interaction is so strong that new states \u2013 cavity polaritons \u2013 are created, that are partially light, partially material excitation. In semiconductors, exciton-polaritons have been the most widely studied type of strongly coupled system. Recently a new phenomenon has been realized exploiting intersubband transitions. The resulting excitations are called intersubband polaritons, and they have two remarkable properties: (i) a bosonic character that is maintained up to high carrier densities since they are not restricted by the Mott transition limit; (ii) large Rabi splittings. Although the scientific community has explored the basic science of intersubband polaritons, their potential for future and innovative optoelectronic devices has been entirely untapped.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["FETOPEN-01-2016-2017 - FET-Open research and innovation actions"], "Funding_scheme": ["RIA - Research and Innovation action"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-01-01"], "Project_ID": ["737017"], "Call_for_Proposal": ["H2020-FETOPEN-1-2016-2017"]}, -{"Partners": ["KATHOLIEKE UNIVERSITEIT LEUVEN"], "EU_Contribution": ["EUR 172 800"], "Project_Title": ["Transnational meanings and makings of class: Polish labour, capital and the state"], "Total_Cost": ["EUR 172 800"], "Country": ["Belgium"], "Project_ACR": ["TRANSCLASS"], "Technology_Description": "Class, as a leading category that explains unequal social relations between labour and capital, emerged out of the context of a national state framework. This research examines how class is made and imagined in instances in which transnational processes of global capitalism release both capital and labour from the confines of a single nation state, and what remains of the nation state\u2019s role as the guardian of particular class interests and in managing change. The answer will be provided by a multi-sited ethnographic analysis of posted work, one of the flagship European Union projects which involves the transnational subcontracting of foreign labour for short-term projects under the provision of service. The analysis will be conducted from the perspective of Polish workers posted to Belgium, their direct employers and the Polish state as the leading European state who posts labour abroad. By bringing to the fore the transnationally and culturally sensitive investigation of class, the research will help to understand current economic situation and power struggles, and to gauge the practical and political possibilities for action towards a more just and equal European society, including providing an informed basis on which to create posted work regulations, currently under the debate by the European Commission. At the theoretical level, the research will offer a fruitful cross-fertilization, whereby ethnographically sensitive, anthropological inquiry will inform industrial relations research and help to reconceptualize class in the transnational era. The action will further my academic development towards acquiring a professorship position and will open up collaborative possibilities on multi-disciplinary projects related to mobility and European transformations with Interculturalism, Migration and Minorities Research Centre at KU Leuven.", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["753438"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CONSIGLIO NAZIONALE DELLE RICERCHE"], "EU_Contribution": ["EUR 168 277,20"], "Project_Title": ["Modern Geospatial Practices for Ancient Movement Praxis"], "Total_Cost": ["EUR 168 277,20"], "Country": ["Italy"], "Project_ACR": ["GeoMOP"], "Technology_Description": "Ancient roads cross-culturally reflect motivations and needs behind social, economic, political and religious relations of past societies; they imposed spatial order on agricultural production, enabled transportation of bulk-goods, mediated hegemonic power, and facilitated urban fabric. Everyday actions of past individuals must have had contributed to the formation of roads. And, in return roads must have had sustained individual (and societal) connectivity. Therefore, considered not only as the container of action, but also the action itself, the road has much more to say on the ancient movement praxis. ", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations"], "From": ["2017-11-01"], "Project_ID": ["747493"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF EDINBURGH"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Birthing Abolition: Reproduction and the Gradual End of Slavery in Brazil"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["BIRTHBRAZIL"], "Technology_Description": "BIRTHBRAZIL is an interdisciplinary project that will analyze how enslaved women\u2019s reproductive trends and practices shaped the gradual abolition of slavery in the middle to large plantation holdings of Rio de Janeiro, Brazil from 1850 (the definitive end of the country\u2019s slave trade) to final abolition in 1888. The project aims to contend that the struggle to end slavery was intimately entangled not only with elite understandings of slave reproduction but also with enslaved women\u2019s own agency. To do so, it examines demographic trends among the enslaved population, elite views of enslaved women\u2019s reproduction, and enslaved women\u2019s own reproductive practices and agency. Like most Atlantic slave societies, the Brazilian slave population was reproduced through imports and not natural growth. Historians have argued that for 19th-century Rio de Janeiro state, harsh labour regimes and disease caused negative growth rates, dismissing the idea of \u201creproductive resistance\u201d\u2014the female enslaved practices of abortion and infanticide as purposeful attacks on the institution of slavery\u2014popular in theories on Caribbean and US slavery. While enslaved women\u2019s fertility control may not have caused negative population growth in 19th-century Rio de Janeiro state, BIRTHBRAZIL hypothesizes that enslaved women\u2019s practices of fertility control played an important symbolic role in how elites understood and approached slavery itself. The findings of BIRTHBRAZIL are expected to demonstrate that enslaved women\u2019s fertility control, both real and imagined, created the opportunity for abolitionists to implement the legal framework that abolished slavery. In doing so, the project provides historical background to current-day debates on reproductive rights, women\u2019s health, and gender equality. The results will be disseminated through an academic monograph, peer-reviewed open-access publications, a website, an international conference, public history blogs, and a series of community lectures.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["747374"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 171 792,60"], "Project_Title": ["Ultra-robust, flexible organic sensors for application in lactic acid sensing and selective biosensing"], "Total_Cost": ["EUR 171 792,60"], "Country": ["United Kingdom"], "Project_ACR": ["Robust OTFT sensors"], "Technology_Description": "The overall objective of \u201cRobust OTFT sensors\u201d is to apply Dr. Nikolka\u2019s expertise in material science and organic electronics to the field of organic sensors. The aim of the specific project is to explore the use of state-of the art conjugated polymers as a platform for flexible, low-cost lactic acid sensors and biosensors. Dr. Nikolka will therefore spend time in Prof. Zhenan Bao\u2019s group (Stanford University), which is world leading in the areas of electronic-human interfaces, e-skin and biological sensing technologies. In Prof. Bao\u2019s group, he will learn the experimental techniques required for work on (bio-) sensors including microfluidics, flow-cell setups or the functionalization of surfaces. To ensure a successful project outcome, Dr. Nikolka will build on his previous work and achievements, such as the discovery of high performance, disorder free polymers (Venkateshvaran*, Nikolka* et al., Nature, 2014) or the demonstration of high operational and environmental stability of high-mobility conjugated polymer through the use of molecular additives (Nikolka et al., Nature Materials, in 2nd stage review). The project is aimed at providing Dr. Nikolka with the techniques and tools to grow as an independent researcher which he will be able to demonstrate during the return phase by combining novel sensors designs with printing techniques pioneered at Cambridge University. \u201cRobust OTFT sensors\u201d will furthermore enable Dr. Nikolka to profit from training and educational programs and allow him to gain essential skills in project management, leadership and financial independency. Finally, it is the goal of the project to create a strong international collaboration between the outgoing and return host laboratories and connect expertise in sensing (Stanford) with the expertise in printed organic semiconductors (Cambridge). This work could lead towards various low-cost sensors for biomedical or lab-on-a-chip applications having a direct and profound impact on society.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["747461"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["LUNDS UNIVERSITET"], "EU_Contribution": ["EUR 173 857,20"], "Project_Title": ["Addressing metalloenzymes for clean energy production with advanced embedding schemes andquantum mechanical methods"], "Total_Cost": ["EUR 173 857,20"], "Country": ["Sweden"], "Project_ACR": ["MetEmbed"], "Technology_Description": "The proposed project aims to develop and apply quantum mechanical (QM) methods targeted at metalloenzymes, for which the methods in use today often fail. The failures are caused by inaccuracies in either 1) the underlying protein structures, 2) the employed QM method or 3) the embedding method that describes electrostatic interactions between the protein environment and the active site (i.e. metal and its nearest ligands). The MetEmbed project addresses 1), 2) and 3) with hydrogenases and polysaccharide monooxygenases (PMOs) as target enzymes. Hydrogenases mediate the reversible conversion of dihydrogen into hydride ions and protons, while PMOs have shown great potential for biofuel production. The overall objective is to investigate the reaction and spin-state energetics for key intermediates in the two proteins' catalytic cycles. To ensure that the underlying structures are accurate, extensive molecular dynamics (MD) simulations with tailored force fields and QM/MM methods will be employed. The adequacy of the QM methods will be ensured by using accurate, multireference QM methods that are known to be well-suited for transition metal systems. Two new multireference QM methods will be applied, namely a multiconfigurational density functional theory hybrid and the density matrix renormalization group method. These methods have high potential for metalloenzymes, but have until now only found little use in this area. To address the effect of the protein electrostatics, an accurate embedding scheme that, contrary to most QM/MM methods, includes the polarization of the environment will be used. The combination of 1) accurate structures, 2) accurate QM methods and 3) polarizable embedding schemes is unprecedented for metalloenzymes. The MetEmbed project will thus predict energetics with a new level of confidence for two systems with high potential in the areas of energy efficiency and low-carbon energy production; both central parts of the HORIZON2020 program.", "To": ["2020-07-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-08-01"], "Project_ID": ["745967"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF YORK"], "EU_Contribution": ["EUR 251 857,80"], "Project_Title": ["African Sky Forests: services, threats and management recommendations"], "Total_Cost": ["EUR 251 857,80"], "Country": ["United Kingdom"], "Project_ACR": ["AFRI-SKYFOR"], "Technology_Description": "Tropical montane forests (TMF) are biodiversity rich and unique ecosystems which provide water to tens of millions of people, among other services such as firewood, medicinal plants, hazard prevention, climate modulation and carbon sequestration. However, TMF remains understudied and over-exploited, particularly in Africa. Predicted climatic changes and trends in population growth will negatively affect the ecological functioning and ecosystem service delivery of these already fragile ecosystems. Therefore, there is an urgent need to better understand these ecosystems and use that information to inform management.", "To": ["2020-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["743569"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 200 194,80"], "Project_Title": ["Chromatin Study of DNA Double Strand Breaks"], "Total_Cost": ["EUR 200 194,80"], "Country": ["Denmark"], "Project_ACR": ["ChroSoDSB"], "Technology_Description": "In stark contrast to common belief, cellular DNA is not de facto safe as it constantly encounters numerous perils. To keep chromosomal DNA intact and to prevent the onset of pathological conditions, such as cancer and premature ageing, which are driven by DNA damage-induced genomic instability, life has evolved appropriate protective mechanisms, collectively referred to as the DNA Damage Response (DDR). A vital branch of the DDR is the response to DNA double-strand breaks (DSBs), arguably the most cytotoxic and mutagenic lesions. DSBs lead to the modification of their local chromatin environment to allow scaffolding of downstream protein factories, comprised of signalling, chromatin remodelling and DNA repair proteins. These DSB processing factories assemble in the context of chromatinised DNA, making chromatin architecture crucial for DSB restoration. Though our understanding of how chromatin status affects the DSB response has significantly progressed in recent years, we are only starting to identify factors regulating this intricate interplay. Moreover, current ways to induce DSB result in random, heterogeneous DNA damage, therefore not allowing the study of the DSB response in a specific chromatin compartment. In order to overcome this technical hurdle and to identify new regulators of DSB signalling and repair, I will use a powerful new method, combining the generation of limited, well-distributed DSBs, exclusively located in either euchromatin or heterochromatin, with specific purification of DSB-containing chromatin protein-complexes. Subsequently, I will select, validate and functionally characterise novel factors that have not yet been implicated in the DSB response, but behave similarly to known DSB-related proteins. By performing this multidisciplinary project, I will obtain new scientific and transferrable skills, thus taking a huge step towards true scientific independence and better career opportunities.", "To": ["2019-06-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["744866"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["USTAV EXPERIMENTALNI BOTANIKY AV CR"], "EU_Contribution": ["EUR 154 720,80"], "Project_Title": ["Widening gene pool of bread wheat by hybridization with Aegilops biuncialis supported by advanced genetic and chromosome genomic approaches"], "Total_Cost": ["EUR 154 720,80"], "Country": ["Czech Republic"], "Project_ACR": ["AEGILWHEAT"], "Technology_Description": "The widening of gene pool of bread wheat (Triticum aestivum) by employing its wild relatives as donors of new alleles and genes will ensure the ability of wheat to sustain yield quality and quantity under adverse environmental conditions. Species from genus Aegilops represent a rich source of agronomically important traits, such as leaf rust resistance, grain nutritional quality and abiotic stress tolerance. To date, the utilization of wild genetic diversity has been hampered by low throughput of methods used to select introgression lines and the lack of knowledge on the genomes of wild relatives. ", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Czech Republic"], "Activity": ["Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["746253"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS"], "EU_Contribution": ["EUR 152 653,20"], "Project_Title": ["European Frontiers: Rural Spaces and Expanding States"], "Total_Cost": ["EUR 152 653,20"], "Country": ["Greece"], "Project_ACR": ["EUROFRONT"], "Technology_Description": "Frontiers are dynamic zones of resistance and negotiation where local actors respond to the political/economic fluctuations of expanding states. Research on Europe\u2019s frontier zones in the historic past has immediate relevance to the modern economic and political landscape, where the expansion of transnational markets is creating new dynamic frontier zones. Yet due to the typical top-down approach employed by archaeologists and historians, the local experience of living in a frontier has been largely overlooked. EUROFRONT adopts an innovative four-field methodology (archaeology, history, geomatics, and ethnography) to investigate two European frontiers in Crete and Dalmatia. Rich datasets will be developed for each region, synthesizing archaeological data, archival materials (e.g. tax registers and cadastral maps), paleoclimate data, and modern oral histories about villages in the regions. Advanced geospatial analyses will be used to detect patterns in population movement, settlement distribution, network connection, and agricultural production. During the project, the researcher will be trained in cutting-edge geomatics technologies, and the skills and knowledge she gains will enhance her reputation as a leading scholar of Early Modern archaeology and history in Europe. Results of the study will provide insight into how frontier communities are shaped by the process of state expansion from an economical, social, political, and environmental perspective. Project dissemination will prioritize publication of the raw data, training other scholars, and sparking an international dialogue about frontier zones that transects geographical and temporal boundaries. The project website and interactive online GIS will be critical deliverables that not only promote the study of frontiers but also give voice to the local experience through publication of maps, photographs, and interviews with local residents.", "To": ["2019-07-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Greece"], "Activity": ["Research Organisations", "Zinovia Papatheodorou", "Tel.: +30 2810 391522", "Fax: +30 2810 391555"], "From": ["2017-08-01"], "Project_ID": ["750483"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FUNDACION DONOSTIA INTERNATIONAL PHYSICS CENTER"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Photochemistry and radiolabelling of gold(III) anticancer prodrugs"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["PhoRAu"], "Technology_Description": "The use of light to activate anticancer prodrugs is nowadays a reality in clinics around the world. Photodynamic therapy is an effective treatment for the localised destruction of cancer cells in a range of tissues and organs. Triggering the antiproliferative activity of chemotherapy agents with spatial and temporal control offers the advantage of reducing side effects and resistance. On the bases of the great success of metal-based drugs (e.g. cisplatin and its derivatives), photoactivatable metal complexes have been investigated for their potential in light-activated therapy. This promising class of molecules is characterised by outstanding photophysical and photochemical features, which can result in novel cytotoxicity mechanisms. Among transition metals, gold has shown promising anticancer features, however no attempt to exploit Au photochemistry for medicinal use has been reported yet.", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2018-02-01"], "Project_ID": ["746976"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["TECHNISCHE UNIVERSITAET MUENCHEN"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Dissipative Self-Assembly: A powerful but unexplored tool to create temporary supramolecular hydrogels"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["DisMolGels"], "Technology_Description": "The aim of this study is to develop molecular temporary hydrogels coupled to an energy dissipating chemical reaction (DisMolGels). Until now, most molecular self-assembled materials operate close to thermodynamic equilibrium, under static conditions, and are thus far from the interesting features biological living \u201cmaterials\u201d display. Biological materials are thermodynamically open and are kept far from equilibrium by a constant input of energy. This mode of self-assembly, one of the requirements of life, is referred to as dissipative or dynamic self-assembly. For this project I will focus on the recreation of part of such dissipative processes, and translating them to our current static hydrogel materials. With that, dynamic hydrogels with entirely new properties, most prominently their tunable lifetime and stiffness, will be developed. To do so, chemical fuels will be used as energy input and simple synthetic peptide derivatives will be constitute the self-assembling building blocks. ", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["747007"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["G-Quadruplex-associated proteins (QAPs) and their role in transcriptional regulation"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["QAPs"], "Technology_Description": "In the human genome, many G-rich sequences have the potential to form 4-stranded non-canonical secondary structures known as G-quadruplexes (G4s). G4 structures have been visualized in nuclei by immunofluorescence and mapped genome-wide to regulatory chromatin regions linked to elevated transcription using G4 chromatin immunoprecipitation and high-throughput sequencing (G4 ChIP-seq). G4s are implicated in gene regulation, DNA replication and genome instability, yet little is known about their protein interaction partners or role in regulating genome activity. ", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["747297"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN"], "EU_Contribution": ["EUR 201 514,50"], "Project_Title": ["The History Play and the British Enlightenment, 1750-1815"], "Total_Cost": ["EUR 201 514,50"], "Country": ["Ireland"], "Project_ACR": ["HISTPLAY"], "Technology_Description": "The aim of this Fellowship is for the researcher, Dr David O\u2019Shaughnessy, to develop the professional prowess, advanced training, high-impact dissemination, and practical experience commensurate with a leading independent researcher in the EU. The researcher will be based for 15 months at the Huntington Library, California (HL) supervised by Professor Kevin Gilmartin and for 12 months at the School of English, Trinity College Dublin (TCD) supervised by Dr Aileen Douglas. Research training will be implemented through an interdisciplinary project investigating the importance of the history play to the discussion and dissemination of Enlightenment ideas in the two main London theatres of the eighteenth century, Covent Garden and Drury Lane, 1750-1815. The key output will be the first monograph to be written on the eighteenth-century history play but the project will also communicate knowledge to a public audience through appropriate activities. On the outgoing phase of the Fellowship, the researcher will access expertise, advanced training, mentoring as well as having access to the Larpent Collection of theatre manuscripts at the HL, the most important archive in the world for the study of eighteenth-century theatre. Due to its unique archive holdings, the HL is the only institution in the world that can host this project; it also has collaborative relationships with Caltech and the University of Southern California (USC) which will benefit the research in significant ways. In TCD the researcher will be given the opportunity to embed his new knowledge through undergraduate and postgraduate teaching, conferences and a symposium, and continued research. The resources of the host institutions will facilitate development of an interdisciplinary and international academic network as well as career-mentoring. The Fellowship will establish the researcher firmly at the centre of eighteenth-century theatre studies and position him for a successful ERC Consolidator application.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["745896"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["JYVASKYLAN YLIOPISTO", "JYVASKYLAN YLIOPISTO"], "EU_Contribution": ["EUR 1 248 560"], "Project_Title": ["Geometry of Metric groups"], "Total_Cost": ["EUR 1 248 560"], "Country": ["Finland", "Finland"], "Project_ACR": ["GeoMeG"], "Technology_Description": "What are the best trajectories to park a truck with several trailers?", "To": ["2022-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-08-01"], "Project_ID": ["713998"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["NATURAL HISTORY MUSEUM"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Adaptations to temperature regimes in sponges: Genomic insights into the developmental and physiological evolutionary changes of early-branching metazoans"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ADAPTOMICS"], "Technology_Description": "Species which inhabit the Antarctic have evolved to exist in some of the most challenging conditions found anywhere on the planet. Marine creatures must cope with sea temperatures generally ranging between 0 to -1.8 degrees Celsius and a food supply which fluctuates widely from summer to winter, rendering their survival difficult. Nevertheless, species have found the means to thrive in such conditions. Their adaptation to cold environments will have included a host of genetic changes, and to date we still know little about the nature of these molecular adaptations, the way these act in vivo, and the exact benefits such changes confer.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2017-06-01"], "Project_ID": ["750937"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER", "WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER"], "EU_Contribution": ["EUR 1 493 750"], "Project_Title": ["Systems Chemistry Approach towards Semiconductive Supramolecular Copolymers with Homo- and Heterometallophilic Interactions"], "Total_Cost": ["EUR 1 493 750"], "Country": ["Germany", "Germany"], "Project_ACR": ["SUPRACOP"], "Technology_Description": "Infinite one-dimensional structures with a metallic main chain of short metal-metal contacts have attracted considerable attention in the field of materials science for many decades due to their excellent optical properties and remarkable dichroism and electrical (semi)conductivity. These materials suffer, however, from decomposition prior to melting and low solubility and processability. The strategy of introducing alkyl side chains of different nature in the past two decades proved to be particularly successful towards better soluble materials or gels with implications in optoelectronics. However, this comes at the price of reduced bulk conductivities leading in some cases to electrical insulators due to the perturbation of the metal-metal contacts.", "To": ["2022-04-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["715923"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["BOURNEMOUTH UNIVERSITY", "INSTITUTUL DE MECANICA SOLIDELOR", "ROBOTNIK AUTOMATION SLL", "STIMPEX SA", "CEDRAT TECHNOLOGIES SA"], "EU_Contribution": ["EUR 513 000"], "Project_Title": ["SMart rObOTs for fire-figHting"], "Total_Cost": ["EUR 909 000"], "Country": ["United Kingdom", "Romania", "Spain", "Romania", "France"], "Project_ACR": ["SMOOTH"], "Technology_Description": "Over the years, changes in modern infrastructure have introduced new challenges to firefighting practices. Training and research programs have been developed to manage these challenges but there are still significant losses from fires each year. In 2013 alone, the fire departments in the USA responded to over 1.2 million fires which resulted in about 3,420 civilian fatalities, 15,925 injuries and property losses of about $12.4 billion dollars. In the UK, 192,600 fires responses, approximately 350 civilian fatalities, 10,300 injuries. The firefighting and rescue functions of the existing equipment and apparatus and their dexterity are limited, particularly in the harsh firefighting environments. The SMOOTH project aims to propose a novel robot-assisted decision making system in smart firefighting to perform searching and rescuing practice in the fire ground, and to facilitate the decision makings with higher efficiency. ", "To": ["2021-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2016 - Research and Innovation Staff Exchange"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-03-01"], "Project_ID": ["734875"], "Call_for_Proposal": ["H2020-MSCA-RISE-2016"]}, -{"Partners": ["DEMOCRITUS UNIVERSITY OF THRACE"], "EU_Contribution": ["EUR 150 932,10"], "Project_Title": ["Proposal title GREEce: modeliNg of the FOREst SEctor EcoNomy"], "Total_Cost": ["EUR 150 932,10"], "Country": ["Greece"], "Project_ACR": ["GREEN FORESEEN"], "Technology_Description": "The economic role of the forest sector in Greece is a neglected field of academic inquiry. Studies of the markets for Greek forest products, are few and far between. This reflects a general lack of investment in the forest sector of the country. An example of this is that the last national forest census was carried out in 1992. Meanwhile, the economic crisis that has plagued the country since 2008 has made matters worse, not only in terms of funds to study the sector but also in terms of environmental outcomes. For instance, as a result of increasing poverty levels, many people have resorted to the use of fuelwood to satisfy their energy needs. This may seem like a good thing, in light of the Renewables Directive's targets for renewable energy adoption. In reality, the switch to fuelwood has led to a severe increase in illegal logging. Despite the numerous and frequent media reports, scientific evidence of this is lacking.", "To": ["2020-06-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-CAR - CAR \u2013 Career Restart panel"], "Coordinated_in": ["Greece"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["743900"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["DIETARY MOLECULAR DIAGNOSTICS SL"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Personalized Metabolomics for Fitness and Training"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["PERMETFIT"], "Technology_Description": "Increasing physical activity (PA) is currently widespread among the population. Thus, in addition to the professional, the amateur and the physically inactive persons being engaged for many different reasons, PA is considered a major driver for optimal health achievement throughout life.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-SE - Society and Enterprise panel"], "Coordinated_in": ["Spain"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-09-01"], "Project_ID": ["748829"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["A Catalytic Method to Form Carbon\u2013Carbon Bonds by Coupling Two Carbon\u2013Fluorine Bonds."], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["FLUOROCROSS"], "Technology_Description": "The aim of the fellowship is to pioneer a synthetic method to form carbon\u2013carbon bonds from the coupling of two carbon\u2013fluorine bonds. This method will result in new routes to fluorinated biaryls, organic molecules that are used in materials science or as the active ingredient in pharmaceuticals and agrochemicals. It will open up new pathways to using inexpensive and environmentally persistent fluorocarbons in synthesis. ", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["745806"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["XILINX IRELAND UNLIMITED COMPANY"], "EU_Contribution": ["EUR 93 933"], "Project_Title": ["Tensor Processing on FPGAs for Artificial Neural Networks"], "Total_Cost": ["EUR 93 933"], "Country": ["Ireland"], "Project_ACR": ["TPANN"], "Technology_Description": "Artificial neural networks have been shown to offer a powerful computing approach to encounter many classification problems as in synthetic vision (e.g. autonomous driving) and artificial intelligence (e.g. AlphaGo). While their implementations are often based on power-hungy CPU- and GPU-installations, first researchers have delivered initial application-specific solutions that demonstrate FPGAs to be a feasible and efficient alternative. This proposal aims at providing a generic reference implementation of ANNs on FPGAs that is tunable towards various application needs by parametrization. Since individual FPGA designs establish enormous costs of entry due to a higher engineering effort on a lower abstration level, an IP core that is available out of the box is a great R&D incentive that enables more researchers and engineers to embrace the emerging efficient heterogeneous computing more quickly and produce innovations and more compact and more efficient products on this basis. Besides this technological advance, this proposal enables a researcher with an enormous experience in mapping computations into FPGA hardware to make a valuable industrial experience in an international context with the major company in this domain. His expertise is ideally complemented with the application experience available at Xilinx who will benefit from opening a new growing market for manufactured FPGA devices. The development of the researcher's skill set is explictly addressed by complementing his academic background with industrial experience and scheduled cooperate trainings. As part of the dissemination activities, his network into the FPGA community is strengthened and approaches towards the ANN community are made.", "To": ["2018-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-SE - Society and Enterprise panel"], "Coordinated_in": ["Ireland"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-05-01"], "Project_ID": ["751339"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Multifunctional luminescent and magnetic nanoparticles for advanced biomedical applications"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["LUMIMAGNET-NANO"], "Technology_Description": "The key goals of the \u201cLUMIMAGNET-NANO\u201d project are: (a) the training of a talented young researcher, Dr. Rosa Mart\u00edn-Rodr\u00edguez, in the fast growing field of science, technology and industrial applications of nanomedicine, where the host and partner institutions have a critical knowledge and expertise; and, (b) the design, development and optimisation of cost-efficient magnetic nanoparticles with multifunctional recovering for biomedical applications.", "To": ["2017-05-17, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-05-18"], "Project_ID": ["658806"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI PAVIA", "UNIVERSITA DEGLI STUDI DI PAVIA", "AVANTEA srl", "FUNDACION CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III"], "EU_Contribution": ["EUR 2 314 029"], "Project_Title": ["Molecular strategies to treat inherited arrhythmias"], "Total_Cost": ["EUR 2 314 029"], "Country": ["Italy", "Italy", "Italy", "Spain"], "Project_ACR": ["EU-rhythmy"], "Technology_Description": "Sudden cardiac death (SCD) is a leading cause of death in western countries: coronary artery disease is the major cause of SCD in older subjects while inherited arrhythmogenic diseases are the leading cause of SCD in younger individuals. After 25 years dedicated to research of the molecular bases of heritable arrhythmias, the PI of this proposal now intends to pioneer gene therapy for prevention of SCD: a virtually unexplored field. The development of molecular therapies for rhythm disturbances is a high risk effort however, if successful, it will be highly rewarding. The PI has envisioned an ambitious and comprehensive project to target two severe inherited arrhythmogenic diseases: dominant catecholaminergic polymorphic ventricular tachycardia (CPVT) and Long QT syndrome type 8 (LQT8). The availability of a clinically relevant model is critical to ensure clinical translation of results: the team will exploit an existing CPVT model and will engineer a knock-in pig to model LQT8. The PI and her team will investigate innovative strategies of gene-delivery, gene-silencing and gene-editing to the heart comparing efficacy of different constructs and promoters. The team will also carefully engineer novel gene-therapy approaches to avoid the development of regional inhomogeneity in protein expression that may facilitate proarrhythmic events. Such a comprehensive approach will provide a most valuable core of knowledge on the comparative efficacy of a broad range of molecular strategies on the electrical milieu of the heart. It is expected that these results will not only benefit CPVT and LQT8 but rather they will foster development of gene therapy for other inherited and acquired arrhythmias.", "To": ["2020-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2014 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations"], "From": ["2015-11-01"], "Project_ID": ["669387"], "Call_for_Proposal": ["ERC-2014-ADG"]}, -{"Partners": ["UNIVERSITA' DEGLI STUDI DI SIENA", "UNIVERSITA DI PISA", "UNIVERSITA DEGLI STUDI DI FIRENZE", "UNIVERSITA PER STRANIERI DI SIENA", "SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO SANT'ANNA", "SCUOLA NORMALE SUPERIORE", "SCUOLA IMT (ISTITUZIONI, MERCATI, TECNOLOGIE) ALTI STUDI DI LUCCA"], "EU_Contribution": ["EUR 160 000"], "Project_Title": ["Brilliant Researchers Impact on Growth Health and Trust in research."], "Total_Cost": ["EUR 160 000"], "Country": ["Italy", "Italy", "Italy", "Italy", "Italy", "Italy", "Italy"], "Project_ACR": ["BRIGHT"], "Technology_Description": "The BRIGHT project aims at enhancing the visibility and perception of researchers among the general population in the Tuscany Region, simultaneously with all the European Researchers\u2019 Night (ERN) initiatives.", "To": ["2018-01-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-NIGHT-2016 - European Researchers' Night"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-06-01"], "Project_ID": ["722944"], "Call_for_Proposal": ["H2020-MSCA-NIGHT-2016"]}, -{"Partners": ["INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Digestive and nutritional indicators of feed efficiency in cattle fed forage-based diets"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["MarkEfficiency"], "Technology_Description": "As the human population approaches 9.5 billion in 2050, and societies as a whole become more affluent, the demand for meat and milk is projected to nearly double. The current challenge facing humanity is to achieve food security in a sustainable manner. As such, sustainable livestock production must be targeted towards the efficient use of feeds not suitable for human consumption. As a result of their symbiotic rumen microbial population, ruminants are strong targets for manipulation as they can convert fibrous forages and low quality nitrogen sources into high protein meat and milk. Evaluation of the feed efficiency of ruminants fed non-competitive feed resources is an important avenue to increase the profitability and sustainability of European ruminant farming systems. Feed efficiency is a complex trait that is lengthy and costly to phenotype. Additionally, in order to provide a comprehensive evaluation of the \u201csustainable\u201d phenotype, newer sustainability parameters, such as methane emissions and nitrogen losses need to be incorporated. Metabolism and digestion have been described as the two most important physiological drivers of variation of feed efficiency in ruminants. Thus, the objective of this proposal is to explore potential biomarkers and microbial indicators of feed efficiency in growing cattle fed forage-based diets to improve our understanding of the physiological basis of efficient animals. Using feed conversion efficiency and residual feed intake as benchmark indexes of efficiency, we will test and improve the use of modern isotopic N fractionation and rumen microbial phylotyping techniques as practical tools to evaluate feed efficiency in ruminants and to better understand and correlate the rumen microbial community signature to an efficiency phenotype. These biomarkers could be used as an early evaluation tool in young animals and in commercial settings for selection and assessment of nutritional management problems.", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2015-09-01"], "Project_ID": ["658126"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["WAGENINGEN UNIVERSITY"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["Following Protein Diffusion in Photosynthetic Membranes with Super Resolution"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["MeaSuRe"], "Technology_Description": "The regulated diffusion of light-harvesting complexes in photosynthetic membranes is essential for photosynthesis, for instance for the redistribution of light-harvesting complexes between Photosystems I and II. To date, however, little is understood about the mobility of these proteins through the highly crowded membrane environment. In contrast to the huge amount of structural research that has been performed on biomolecules in the past, research on the dynamics is lagging far behind. The major limitation is the fact that the nanometer size regime of biomolecules is not accessible by classical optical techniques owing to the diffraction limit of light. To overcome this problem, we propose to use plasmonic nanoantennas, which are able to confine light at the nanoscale. In combination with Fluorescence Correlation Spectroscopy (FCS) this will allow measuring protein mobility in photosynthetic membranes with high, tens of nanometers, resolution. Directional and functional protein movement will be induced by illumination of the chloroplasts using specific light conditions; simultaneously following the protein movement will give new insights in how plants optimize their light harvesting capacity under fluctuating light conditions. The new nanoantenna-FCS based method, which we will develop to measure the diffusion of membrane proteins with nanometer resolution, has the potential to become widely used for nanobioimaging and ultrasensitive biosensing.", "To": ["2017-09-13, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-14"], "Project_ID": ["655542"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["INSTITUTO DE ASTROFISICA DE CANARIAS"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Polarimetry of Anomalous Microwave Emission: Implication for B-mode Polarization Detection and Galactic Science"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["PolAME"], "Technology_Description": "Anomalous Microwave Emission (AME) is potentially polarized in the frequency range [1-100] GHz. The polarization properties of this astrophysical signal have to be characterized and understood completely for one willing to remove Galactic foregrounds in order to detect B-mode polarization for cosmology. The characterization of AME polarization properties is also fundamental in term of Galactic Astrophysics to understand the mechanisms producing the AME. The PolAME project aims to use the QUIJOTE-CMB experiment and its two instruments (the MFI and the TGI) for measuring the degree of polarization of the AME in the domain range [10-30] GHz on a sample of selected sources. This new data, in addition to new C-BASS data and the WMAP and PLANCK maps and ancillary data will be compared to theory and state-of-the-art modelling results. The Galactic science community will greatly benefit the new advances that will be provided by the PolAME project. The main outcome of this project will lead to a stronger characterization of the Galactic Polarized Foregrounds which is fundamental for cosmology. Knew knowledge will be produced about our understanding of the nature of the AME and dust grain evolution processes in our Galaxy.", "To": ["2017-12-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2016-01-01"], "Project_ID": ["658499"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE", "UNIVERSITAET FUER BODENKULTUR WIEN", "MADERA PLUS CALIDAD FORESTAL SL"], "EU_Contribution": ["EUR 675 000"], "Project_Title": ["Wood phenotyping tools: properties, functions and quality"], "Total_Cost": ["EUR 675 000"], "Country": ["France", "Austria", "Spain"], "Project_ACR": ["TOPWOOD"], "Technology_Description": "The objective of TOPWOOD is to build a four-year scientific exchange program about the test and development of medium and high-throughput phenotyping measurement and analysis tools for selected basic wood properties in the laboratory and in the field (TOols for Phenotyping WOOD-TOPWOOD). The participants wish to exchange knowledge and experience for sharing and expanding skills, improving existing tools and developing new original measuring devices for wood properties involved in studies of wood quality and of wood biological functions. The phenotyping tools and methods of analysis developed and improved in TOPWOOD are intended to be used by the participants to investigate the genetic and environmental determinism of key wood properties involved in forest tree adaptation, as well as in wood production and wood quality for the forest and wood industries. The participants of TOPWOOD are three academic institutions and one private company from three European Union countries, Austria, France and Spain, and one third country, Argentina. ", "To": ["2019-03-31, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-RISE-2014 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-04-01"], "Project_ID": ["645654"], "Call_for_Proposal": ["H2020-MSCA-RISE-2014"]}, -{"Partners": ["INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Single cell biophysics of bacterial cell shape"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["BACTOSHAPE"], "Technology_Description": "In bacteria, the rigid external cell wall (CW) and the intracellular actin-like (MreB) cytoskeleton are major determinants of cell shape. Synthesis and chemical composition of the CW, a three dimensional polymer network that is one of the most prominent targets for antibiotics, are well understood. However, despite decades of study, little is known about the complex CW ultrastructure and the molecular mechanisms that control cell shape in time and space. MreB homologues assemble into dynamic membrane-associated structures thought to control shape by serving as organizers for the movement and assembly of macromolecular machineries responsible for CW biogenesis. However, the mechanistic details used by the MreB cytoskeleton to fulfill this role remain to be elucidated. ", "To": ["2017-03-31, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2015-04-01"], "Project_ID": ["660935"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA", "LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN", "UNIVERSITEIT GENT", "UNIVERSITEIT UTRECHT", "TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK", "THE REGENTS OF THE UNIVERSITY OF CALIFORNIA", "CORNELL UNIVERSITY"], "EU_Contribution": ["EUR 859 500"], "Project_Title": ["Colloidal Nanomaterials for Smart Applications"], "Total_Cost": ["EUR 859 500"], "Country": ["Italy", "Germany", "Belgium", "Netherlands", "United States", "United States", "United States"], "Project_ACR": ["COMPASS"], "Technology_Description": "\"The COMPASS project unites key players in Europe and the US with the aim to advance the field of colloidal nanocrystal (NC) synthesis and assembly and their exploitation in photonics, sensing, energy conversion and medicine. COMPASS aims to (i) develop colloidal NCs with desired properties by controlling their size, shape and composition, and to demonstrate routes allowing for large production volumes with nearly identical size and shape; (ii) develop approaches for NC self-assembly in ordered superlattices constituting NC solids with novel properties; (iii) understand the optoelectronic properties of novel NC-based materials by advanced optical and scanning probe spectroscopy methods, and explore pathways for their implementation in light emission, sensing, energy conversion and medicine; (iv) establish a consolidated network between leading EU and US institutes to provide a stimulating international environment for talented young researchers; (v) advance the level of R&D in Europe and the US and foster technology transfer and dissemination; (vii) raise the awareness of the general public on the prospects of NC materials in future technologies. Young scientists will be formed by \"\"training by research\"\" in long term stays at host labs and by lecture series held in the network that cover specific research topics, technology transfer and management/communication skills, leading to an interdisciplinary and international formation. The exchange will consolidate existing initial links between some of the lead scientists in COMPASS and establish a long lasting network that will have strong impact on science and education with significant repercussions in industry. The work plan is divided in 5 strongly linked workpackages that deal with Management, NC Fabrication, Self Assembly and Surface Functionalization, Photonics and Optoelectronics, and Energy Conversion. COMPASS will be guided by an executive board that consists of the coordinator and the lead PIs of the partners.\"", "To": ["2020-02-29, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Chiara Andreoli", "Tel.: +3901071781854", "Fax: +39 010 7170817", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-03-01"], "Project_ID": ["691185"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["OXFORD BROOKES UNIVERSITY", "THE REGENTS OF THE UNIVERSITY OF CALIFORNIA"], "EU_Contribution": ["EUR 269 857,80"], "Project_Title": ["(Un)Just NeighbourhoodsSocio-Spatial Justice in Urban Neighbourhoods"], "Total_Cost": ["EUR 269 857,80"], "Country": ["United Kingdom", "United States"], "Project_ACR": ["Justhood"], "Technology_Description": "Rapid urbanisation, growing process of globalisation, and the neoliberal hegemony have culminated in the omnipresence of socio-spatial inequalities at the neighbourhood scale regarding racial segregation, deprivation, stigmatisation, and degradation. European and North American cities, among others, have initiated neighbourhood-oriented urban redevelopment schemes to mitigate the burden of urban injustice. However, there is no integrated framework to evaluate their achievements, the contribution of urban neighbourhoods to just cities has not been systematically investigated. To address this lacuna, the project conceptualises the idea of (un)just neighbourhoods from socio-spatial justice perspective and develops an evaluation framework for measuring key qualities of socio-spatial justice at the neighbourhood scale.", "To": ["2021-01-09, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-10"], "Project_ID": ["748452"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ANGLIA RUSKIN UNIVERSITY HIGHER EDUCATION CORPORATION"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Pluralistic Economics for Development in Green Economic Enhancement"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["PEDIGREE"], "Technology_Description": "The question of which economic framework (or sets of frameworks) is (are) appropriate for providing policy prescriptions conducive to ecological sustainable has gained renewed interest within the community of ecological economists and political economists. To help answer this question I propose to investigate the suitability of four economic frameworks \u2014 neoclassical environmental economics, non-Walrasian neoclassical environmental economics, institutional ecological economics, and ecological Marxian political economy, for providing effective and coherent policy prescriptions for renewable and sustainable energy resources, specifically for electricity generation.", "To": ["2017-12-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["655274"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["DE MONTFORT UNIVERSITY"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Design, fabrication and optimization of a novel integrated UV-microwave assisted catalytic reactor for the continuous flow treatment of wastewater"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["UVMWREACT"], "Technology_Description": "UVMICROCAT uses an innovative catalytic mesh assisted by a combination of UV and microwave technology for fast and effective treatment of large volumes of wastewater for water re-use.", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["661048"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Unveiling Stomata 24/7: Using Stable Isotopes and COS to quantify diurnal and nocturnal carbon and water vegetation-atmosphere Fluxes under future climate scenarios"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["USIFlux"], "Technology_Description": "Rising atmospheric CO2 concentration, increasing temperature and altered precipitation patterns dramatically impact the terrestrial biosphere with important consequences for all biogeochemical cycles. Predictions of carbon (C) and water exchange between vegetation and the atmosphere require detailed mechanistic understanding of how plants control water loss and C gain through their stomatal pores. Currently, global circulation models incorporate formulations of stomatal conductance (gs) based on stomatal optimisation theory. However, these models ignore gs regulation: (1) during night time, despite clear evidence for significant nocturnal transpiration, (2) in non-vascular plants and (3) during leaf development and senescence. To reduce the uncertainty associated with current C and water fluxes in models, we need to incorporate robust predictions of gs in response to novel environmental conditions (higher temperature, decreased water availability and elevated CO2). To fill these gaps, USIFlux, will develop a novel tracing technique to measure gs during the dark, when fluxes are an order of magnitude smaller than during the day. To do so, we will combine measurements of COS (carbonyl sulphide) uptake with CO18O fluxes and changes in the oxygen isotope composition (\u03b418O) of water in leaves. We will relate the response of gs at night to changes in gs during the day and in response to drought and elevated CO2. These measurements will be coupled to an experiment to investigate stomatal regulation during leaf ontogeny and in different life forms. Here, we will challenge the stomatal optimisation theory in life forms lacking active stomatal control (mosses and brackens) and during leaf development, when leaf construction costs constrain the optimisation of C gain. Empirical formulations arising from these experiments will be incorporated into large-scale soil-vegetation-atmosphere transfer models to explore their impact at larger scales.", "To": ["2018-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2016-04-01"], "Project_ID": ["653223"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["UNIVERSIDAD DE SANTIAGO DE COMPOSTELA"], "EU_Contribution": ["EUR 239 191,20"], "Project_Title": ["Designing Novel Phonon Valve Device through Ferroic Domain Wall Engineering"], "Total_Cost": ["EUR 239 191,20"], "Country": ["Spain"], "Project_ACR": ["PHONON-VALVE"], "Technology_Description": "Much of the major technological breakthroughs occurring in the last few decades rely on our enhanced capability to control and manipulate two particles: electrons (both charge and spin) and photons. Achieving a similar degree of control over phonons would be extraordinarily valuable as we will be able to channel thermal energy at will \u2013thus propelling new possibilities for energy management\u2013 as well as the development of a completely novel technology for logic, data storage devices and computing mechanisms based on phonons.", "To": ["2019-09-25, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-26"], "Project_ID": ["708129"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITA CA' FOSCARI VENEZIA"], "EU_Contribution": ["EUR 180 277,20"], "Project_Title": ["Uncovering information in fluctuating CLimate systems: An oppoRtunity for solving climate modeling nodes and assIst local communiTY adaptation measures"], "Total_Cost": ["EUR 180 277,20"], "Country": ["Italy"], "Project_ACR": ["CLARITY"], "Technology_Description": "A consistent picture of climate variability is pivotal for understanding its evolution. CLARITY intends to apply advanced statistical methods developed in the field of statistical physics to analyze, interpret and incorporate into modelling strategies observed, reconstructed, as well as simulated climate data. To achieve this ambitious goal valuable information from fluctuations in climate records will be uncovered. The obtained results will constitute the input for a Bayesian modelling strategy, aimed then at improving modelling reliability. Once operational, this approach will be applied to a series of climatically relevant issues. On a local scale (city of Venice, Italy), particularly, climate records related to temperature, humidity and the ultraviolet radiation exposure of city\u2019s school populations will be collected and used to obtain projections that can be of assistance to community needs. ", "To": ["2018-05-08, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-05-09"], "Project_ID": ["701785"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["INSTITUT CURIE"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Evolutionary conserved T cells specific for a microbial metabolite: deciphering their development in the thymus and mapping their interactions with the gut microbiota in vivo."], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["MAIT"], "Technology_Description": "Mucosal Associated Invariant T cells (MAITs) represent an evolutionary conserved subset that express a semi-invariant TCR recognizing a new class of microbial metabolite antigens presented by the MHC class Ib molecule, MR1. In addition to their wide anti-microbial specificity, the high inter-species conservation of both MR1 and invariant TCR infers an important biological role for MAITs. MAITs are abundant in human blood (1-8 % of T cells), mucosa and liver (20-50%). After development in the thymus, MAITs reach the periphery where they acquire a memory phenotype and expand in a process that requires a commensal flora, indicating that MAITs play a role in host-commensals interactions. Admittedly MAITs blood frequency is modified in several pathologies in which dysbiosis of the gut microbiota has been implicated such as IBD, MS, type 2 diabetes and obesity.", "To": ["2018-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2016-04-01"], "Project_ID": ["706353"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["INSTITUT CURIE"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Fibroblasts in the Biology of Rectal Cancer Progression"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["FiBRO"], "Technology_Description": "Although the therapeutic strategies adopted in the last years for the clinical management of patients with rectal cancer have improved patient\u2019s quality of life, tumor relapse still constitutes to be a factor that determines patient survival. These patients, usually treated with chemo-radiotherapy (CRT), often develop a CRT-induced fibrosis, which is characterized by an overgrowth of fibroblasts at tumor-treated areas. The importance of tumor stroma for the development, progression and invasion of cancer is increasingly gaining weight, however, the biological basis of fibrosis, as well as the consequences that it has in terms of therapy resistance and tumor relapse remain unknown. The major objective of this proposal is to understand the effect of CRT on fibroblasts and its consequences on tumor relapse and formation of distant metastasis. To reach this, we propose a multidisciplinary approach that combines the analysis of unique patient-derived biological samples using innovative and advanced techniques in molecular and cell biology. More specifically, using a proteomic approach and primary cultures of fibroblasts derived from rectal tumors taken before and after CRT from the same patient, we will determine the effect of CRT on the molecular alterations in fibroblasts. Then, using 3D in vitro models we will determine if CRT-derived fibroblasts play a role in therapy resistance, proliferation and invasion of cancer cells, while ortothopic mouse models will be used to test if CRT-derived fibroblasts can trigger rectal cancer progression and metastasis. Finally, using previously collected clinical data of rectal cancer patients we will analyze if tumor relapse is related to the appearance of fibrosis and, if it has a positive or negative prognosis value", "To": ["2018-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2016-04-01"], "Project_ID": ["659776"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["WAGENINGEN UNIVERSITY", "WAGENINGEN UNIVERSITY", "UNIVERSITEIT UTRECHT", "RIJKSUNIVERSITEIT GRONINGEN", "UNIVERSITY OF LEEDS", "INSTITUTO NACIONAL DE PESQUISAS ESPACIAIS"], "EU_Contribution": ["EUR 2 269 688,76"], "Project_Title": ["New constraints on the Amazonian carbon balance from airborne observations of the stable isotopes of CO2"], "Total_Cost": ["EUR 2 269 688,76"], "Country": ["Netherlands", "Netherlands", "Netherlands", "Netherlands", "United Kingdom", "Brazil"], "Project_ACR": ["ASICA"], "Technology_Description": "Severe droughts in Amazonia in 2005 and 2010 caused widespread loss of carbon from the terrestrial biosphere. This loss, almost twice the annual fossil fuel CO2 emissions in the EU, suggests a large sensitivity of the Amazonian carbon balance to a predicted more intense drought regime in the next decades. This is a dangerous inference though, as there is no scientific consensus on the most basic metrics of Amazonian carbon exchange: the gross primary production (GPP) and its response to moisture deficits in the soil and atmosphere. Measuring them on scales that span the whole Amazon forest was thus far impossible, but in this project I aim to deliver the first observation-based estimate of pan-Amazonian GPP and its drought induced variations. ", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2015-09-01"], "Project_ID": ["649087"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["TECHNISCHE UNIVERSITAET ILMENAU", "AVL LIST GMBH", "COVENTRY UNIVERSITY", "FLANDERS MAKE VZW", "INFINEON TECHNOLOGIES AG", "KATHOLIEKE UNIVERSITEIT LEUVEN", "SKODA AUTO A.S.", "UNIVERSITA DEGLI STUDI DI PAVIA", "UNIVERSITE DE TECHNOLOGIE DE COMPIEGNE", "Kompetenzzentrum - Das Virtuelle Fahrzeug, Forschungsgesellschaft mbH", "VOLVO PERSONVAGNAR AB"], "EU_Contribution": ["EUR 3 833 413,20"], "Project_Title": ["Interdisciplinary Training Network in Multi-Actuated Ground Vehicles"], "Total_Cost": ["EUR 3 833 413,20"], "Country": ["Germany", "Austria", "United Kingdom", "Belgium", "Germany", "Belgium", "Czech Republic", "Italy", "France", "Austria", "Sweden"], "Project_ACR": ["ITEAM"], "Technology_Description": "\"The main target of the ITEAM project is to establish and sustainably maintain the European training network with high grade of interdisciplinarity, which will train strong specialists skilled in research and development of novel technologies in the field of multi-actuated ground vehicles (MAGV). The global goals are: (i) Advance of European postgraduate education in the area of environment- and user-friendly vehicle technologies that highly demanded by the European industry and society; (ii) Reinforcement of cooperation between academia and industry to improve career perspectives of talented graduates in both public and private sectors; (iii) Creation of strong European research and innovation group making determinant contributions to next generations of multi-actuated ground vehicles. To achieve the project objectives, the consortium unites 11 beneficiaries and 5 partner organizations from 9 European countries including 7 universities, 2 research centres, and 7 non-academic organizations. Distinctive feature of the ITEAM network is the concept of interaction of three research clusters: \"MAGV integration\", \"Green MAGV\", \"MAGV Driving Environment\". Within these clusters, the training concept will be based on intersectoral cooperation and will cover domains of (i) basic research, (ii) applied research, and (iii) experimentations. The ITEAM project will provide the first-of-its kind European training network in Ground Vehicles at doctorate level to fill up the niche in private sector and industry with researcher-practitioners. The proposed network will be developed as innovative, multidisciplinary, engineering product-oriented and project-based program to train the scientists by integrating cutting-edge research methods of ground vehicles, electric/mechatronic systems, environmental engineering and applied intelligent control. The ITEAM network measures will guarantee excellent career prospects for participating researchers both in industrial and academic sectors.\"", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-01-01"], "Project_ID": ["675999"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["INSTITUT CURIE", "INSTITUT CURIE"], "EU_Contribution": ["EUR 2 499 697"], "Project_Title": ["Chromatin Adaptations through Interactions of Chaperones in Time"], "Total_Cost": ["EUR 2 499 697"], "Country": ["France", "France"], "Project_ACR": ["ChromADICT"], "Technology_Description": "A central question in chromatin biology is how to organize the genome and mark specific regions with histone variants. Understanding how to establish and maintain, but also change chromatin states is a fundamental challenge. Histone chaperones, escort factors that regulate the supply, loading, and degradation of histone variants, are key in their placement at specific chromatin landmarks and bridge organization from nucleosomes to higher order structures. A series of studies have underlined chaperone-variant partner selectivity in multicellular organisms, yet recently, dosage imbalances in natural and pathological contexts highlight plasticity in these interactions. Considering known changes in histone dosage during development, one should evaluate chaperone function not as fixed modules, but as a dynamic circuitry that adapts to cellular needs during the cell cycle, replication and repair, differentiation, development and pathology.", "To": ["2021-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-ADG-2015 - ERC Advanced Grant"], "Funding_scheme": ["ERC-ADG - Advanced Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2016-07-01"], "Project_ID": ["694694"], "Call_for_Proposal": ["ERC-2015-AdG"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI PAVIA", "UNIVERSITA DEGLI STUDI DI PAVIA", "ISTITUTO NAZIONALE DI FISICA NUCLEARE"], "EU_Contribution": ["EUR 1 509 000"], "Project_Title": ["3-Dimensional Maps of the Spinning Nucleon"], "Total_Cost": ["EUR 1 509 000"], "Country": ["Italy", "Italy", "Italy"], "Project_ACR": ["3DSPIN"], "Technology_Description": "How does the inside of the proton look like? What generates its spin?\u20283DSPIN will deliver essential information to answer these questions at the frontier of subnuclear physics.", "To": ["2020-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations"], "From": ["2015-07-01"], "Project_ID": ["647981"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Unravelling the mechanisms regulating cellular fitness during embryonic development"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["CFED"], "Technology_Description": "Understanding the mechanisms that eliminate unfit cells during development is key not only for proper organ formation but also to prevent tissue degeneration in the adult. Cell competition is a fitness quality control mechanism that occurs between cells of differing fitness levels and results in the selective elimination of those cells that, although viable, are deemed to be less fit than their neighbours. Cell competition is conserved from Drosophila to mammals and although some important regulators of this process have been identified, the mechanisms by which less-fit cells are eliminated are not well understood. Preliminary work in the Rodriguez laboratory has identified the mTOR pathway, a key metabolic sensor, as a possible regulator of cell competition in pluripotent stem cells. A small molecule screen for modulators of cell competition identified that inhibiting mTOR enhances defective pluripotent stem cell elimination during competition, and further studies revealed that mTOR activity is decreased in loser cells when confronted with winner cells. I will study the possibility that mTOR acts as a sensor of the competitive nature of pluripotent stem cells. The specific aims of this project are to find what pathways lead to differential mTOR activation during competition and unravel the mechanisms by which loss of mTOR leads to the elimination of defective stem cells. To answer these questions I will use mouse embryonic stem cells, as well as validate the in vivo relevance of my findings by studying the mouse embryo.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["709010"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["Consortium of European Research Libraries"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["PATRIMONiT. From Cheap Print to Rare Ephemera: 16th-Century Italian 'Popular' Books at the British Library"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["PATRIMONiT"], "Technology_Description": "Large quantities of 16th-Century Italian \u2018popular\u2019 books \u2013 the books read or \u2018listened to\u2019 by everyone during the Early Modern Period, printed with poor quality material and having usually a short life expectancy \u2013, sometime after the 16th century found their way to the UK to join the largest single collection of Italian 16th-century books in the world, that is the British Library (BL). This library preserves today a substantial number of early Italian editions which do not survive in any Italian library and are still not adequately recorded.", "To": ["2018-01-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Other"], "From": ["2016-02-01"], "Project_ID": ["659625"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["DE MONTFORT UNIVERSITY", "UNIVERSITAT PASSAU", "UNIVERSIDAD POLITECNICA DE MADRID", "AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH", "NOLDUS INFORMATION TECHNOLOGY BV", "PHILIPS ELECTRONICS UK LIMITED", "TECHNISCHE UNIVERSITAET WIEN", "ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS", "INGENIERIA Y SOLUCIONES INFORMATICAS DEL SUR, SOCIEDAD LIMITADA", "UNIVERSITY OF ULSTER"], "EU_Contribution": ["EUR 3 874 054,68"], "Project_Title": ["Advanced TeChnologies and PlatfoRm fOr Smarter ASsisted LivING"], "Total_Cost": ["EUR 3 874 054,68"], "Country": ["United Kingdom", "Germany", "Spain", "Austria", "Netherlands", "United Kingdom", "Austria", "Greece", "Spain", "United Kingdom"], "Project_ACR": ["ACROSSING"], "Technology_Description": "Smart Home (SH) provides a promising approach to assisted living for the ageing population. Yet it still remains a challenge to develop and deploy such solutions in a large scale due to the lack of an easy-to-use technology infrastructure and application exemplars. This problem arises from the nature of the SH field: multidisciplinary, diverse in its applications, and with multiple stakeholders. Whilst a one-size-fits-all technology infrastructure seems unlikely, alternatives are still missing. In addition, an effective approach to cross-discipline, cross-sector understanding for best practices has so far not been seen. ", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2015-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["676157"], "Call_for_Proposal": ["H2020-MSCA-ITN-2015"]}, -{"Partners": ["INSTITUT CURIE"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Functions of Integrins in Mammary Stem Cell Activity and Tumorigenesis"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["INTEGRISTEM"], "Technology_Description": "Understanding the functional interactions between mammary epithelium and its microenvironment, with a particular focus on the stem cell niche, represents a challenge for developmental and cancer biologists. Mammary epithelium is a bilayer, with a layer of luminal cells, producing milk, and a layer of basal myoepithelial cells. Both layers contain clonogenic stem/progenitor cells, which ensure the drastic epithelial expansion in puberty and pregnancy. Whilst basal stem cells are thought to be bipotent, luminal progenitors appear to be lineage-restricted in normal gland. Recent studies indicated that basal-like breast tumors, notably those with BRCA1 mutations, might originate from luminal progenitors. Our project aims to elucidate the role of integrin receptors for Laminin, major component of the mammary basement membrane, in the regulation of the luminal progenitor function during normal mammary development and tumorigenesis. To this end, \u03b13 and \u03b16 integrin chains were deleted from mammary luminal cells in vivo using CreLoxP system. Cre expression was driven to luminal progenitors by the Blg promoter, activated in this cell population in adult virgin mice and further on, during lobulo-alveolar development in pregnancy. The stem cell activity and the maintenance of the stem cell populations in mutant mammary glands will be analyzed at different developmental stages. Morphogenesis, proliferation, survival, differentiation as well as the regenerative and clonogenic potential of the mutant epithelium will be examined. We will study the cytoskeleton organization and the capacity of mutant cells for baso-apical polarization. To analyze the responses of integrin-depleted cells to hormones and growth factors at the molecular level, organotypic ex vivo cultures will be employed. The impact of Laminin-binding integrins on abnormal luminal progenitor amplification during tumor initiation will be tested in a mouse model of basal-like breast cancer induced by p53 and BRCA1 loss.", "To": ["2018-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2016-05-01"], "Project_ID": ["704960"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Methodologies Yielding CLimate IMpact Assessments Through Economics"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["MYCLIMATE"], "Technology_Description": "Humans rely for their food on agricultural products. Agricultural production relies on soil, climate, agricultural inputs, and farmers. The importance of climate and soil inputs has been recently reconsidered in agricultural production. However, the quantification of the impact of climate change on agricultural production has been conducted with regression methods that impose undesired assumptions on the obtained results. If it is true that climate is changing, an estimation of climate change impacts on agriculture free of undesired assumptions is the key to understanding a strategy towards a sustainable future. Going beyond the methodological approaches proposed in previous studies, in this action I bridge the gap between production economics and the agronomic and climate economics literature.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2017-09-01"], "Project_ID": ["705360"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["INSTITUT CURIE", "INSTITUT CURIE"], "EU_Contribution": ["EUR 1 999 900"], "Project_Title": ["Unravelling the Genomic Targets of Drugs Using High-Throughput Sequencing"], "Total_Cost": ["EUR 1 999 900"], "Country": ["France", "France"], "Project_ACR": ["Drug-Seq"], "Technology_Description": "This proposal is centred on the development of small molecule probes derived from DNA damaging agents to identify their genomic targets using a novel unbiased approach. Although, several genotoxic drugs have been used for decades to treat cancers, the exact mechanisms by which they operate are not fully understood. It is established that these compounds interfere with the processes of transcription and replication, thereby promoting genomic instability and cell death. However, there is as yet no genome-wide map of the exact location of sites that are putative targets for these drugs in vivo. This information is critical to understand and rationalize cellular responses to genotoxic agents. Here, we propose to develop an innovative discovery- based methodology that will combine click chemistry in situ, affinity pull-down techniques and high throughput DNA sequencing (Drug-Seq), to identify the genomic interactome of DNA damaging drugs in order to elucidate their cellular activity at the molecular level. Two independent lines of enquiry will be followed. Firstly, we will establish the genomic interacting landscape of landmark drugs including etoposide, camptothecin and cisplatin using Drug-Seq. Secondly, we will perform regular chromatin immuno- precipitation sequencing (ChIP-Seq) of selected proteins linked to the cellular response of interest to validate Drug-Seq and further identify druggable genomic sites. An important aim of this proposal is to establish a universal methodology to decipher small molecule/genome interactions in vivo that trigger a particular response in disease-relevant models. We also seek to interrogate the role of chromatin in regulating drug/genome interactions and to define whether it is possible to act on the epigenome to modulate the activity and specificity of these drugs. Collectively, we anticipate our study will lay down the foundation for personalized medicine with the implementation of rational rather than empirical clinical protocols.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2014 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2015-09-01"], "Project_ID": ["647973"], "Call_for_Proposal": ["ERC-2014-CoG"]}, -{"Partners": ["ANGLIA RUSKIN UNIVERSITY HIGHER EDUCATION CORPORATION"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["\u2018Reciprocal Encounters\u2019 - Young Adults Leaving Care"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ReProCounters"], "Technology_Description": "The objective of this proposal, \u2018Reciprocal Encounters \u2013 Young Adults Leaving Care\u2019, is not only to produce preventive, client-based social work guidelines regarding how to search for the best ways to support the well-being of young adults with substitute care experiences and the process of their deinstitutionalisation or leaving substitute care, but it will also use a complementary participatory research methodology to explore the research questions, undertaking research with young adults, not just on them, thus delivering user-driven results.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["702989"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["INSTITUT CURIE"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["In vivo analysis of neuromuscular junction stability in zebrafish models of amyotrophic lateral sclerosis"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["NMJALS"], "Technology_Description": "Amyotrophic lateral sclerosis (ALS) is a late onset, lethal neurodegenerative disease of motor neurons that affects about 2 in 100,000 individuals per year. Different genetic mutations have been described in patients, but the genes involved seem unrelated and the causes of the disease appear complex and are still largely not understood. Of relevance, the destabilisation of neuromuscular junctions (NMJ) may be an early event, preceding neuronal death, making them an interesting therapeutic target to slow down disease progression. The goal of the study is to characterise the molecular organisation and dynamics of NMJ, in particular of cell adhesion molecules, in order to understand the mechanisms of maintenance of NMJ by analysing defects in their organisation in ALS contexts. Technically, we plan to combine neuron biology, quantitative cell biology and computational tools to reach a precise molecular understanding of the dynamic equilibrium of NMJ in zebrafish, an excellent vertebrate model for live imaging. We will develop innovative methods of super-resolution microscopy and of quantification of protein turnover using a fluorescent molecular clock. This precise molecular characterisation of the NMJ will allow detecting subtle early changes in the NMJ that occur before neuronal degeneration starts, in fish carrying mutations described in ALS patients. The project will lead to the identification of key proteins for NMJ stabilisation and enable the analysis of regulatory elements of this stability, especially the cytoskeleton. ", "To": ["2017-11-15, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2015-11-16"], "Project_ID": ["661527"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Mannan-related enzymes of wheat endosperm"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["MANAN"], "Technology_Description": "European society and economy relies on the productivity of staple food, such as wheat. Plant cell walls are a centrepiece of plant development and tuning their biosynthesis could improve the productivity and the quality of wheat grain. Although the structure of cell wall polysaccharides is relatively well-documented, little is known about their biosynthesis. The project proposes for the first time 1) to explore the structure, organisation and function of mannan, a cell wall polysaccharide that impacts on wheat grain development, and 2) to investigate the function of four putative genes involved in the mannan biosynthesis, using a combination of well established and new methodologies (enzymatic fingerprinting, FT-IR microspectroscopy and MALDI-MS imaging). This research is of potential interest to various industrial sectors (e.g., plant breeding, milling and biofuel industries) active in Europe and represents a good opportunity to improve competitiveness of European agriculture. Within the host institute (INRA, France), which is a World leader for agricultural sciences, the supervisor is internationally renowned for its contribution in the general understanding of plant cell walls. The host will offer the opportunity to the fellow to develop a sound knowledge in biochemistry and molecular biology and will contribute to improve his managerial skills. In return, the fellow who has a strong expertise in microscopy and enzymatic activity assays will implement these techniques in the host institution. The fellow will have the opportunity to disseminate his knowledge during various events towards audiences of scientists, students and the general public. The fellow will access to all the facilities, logistics, and equipment necessary for the good implementation of his project. In summary, this innovative project will contribute to European excellence and will offer the training the fellow needs to pursue his career as an independent principal investigator in plant science.", "To": ["2018-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2016-11-01"], "Project_ID": ["708329"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["INSTITUT CURIE"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Membrane-ezrin-actin interactions mediated by ezrin binding proteins in reconstituted systems"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["membrane-ezrin-actin"], "Technology_Description": "Microvilli are tube-like membrane protrusions containing bundles of actin filaments located at the apical surface of epithelial cells. A key component of these microvilli is ezrin, a member of the Ezrin/Radixin/Moesin protein family, which provides a regulated linkage between the plasma membrane and the actin cytoskeleton. The critical role of ezrin in microvillar morphogenesis has been demonstrated. However, how ezrin is recruited to the apical surface of the cells and how ezrin contributes to the stability of microvillar morphogenesis remain elusive. Recently, a few ezrin binding partners, such as EBP50 and Eps8, have been identified and shown to function synergistically with ezrin in membrane and actin remodelling in cells. The precise mechanisms and implications of their interactions in microvillar morphogenesis are not well understood. Lately, I-BAR domain protein IRSp53 was found to colocalize with ezrin in microvilli and interact with both EBP50 and Eps8, as ezrin does. Given that I-BAR domain proteins participate in the formation of many cellular protrusions, such as filopodia, ezrin and I-BAR domain proteins may work synergistically in membrane remodelling. ", "To": ["2017-12-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2016-01-01"], "Project_ID": ["656442"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 246 668,40"], "Project_Title": ["Linking the intrinsic protein dynamics to function in glutamate transporters"], "Total_Cost": ["EUR 246 668,40"], "Country": ["France"], "Project_ACR": ["MEMDYN"], "Technology_Description": "The alternating access model of how membrane-embedded transport proteins translocate substrates across biological membranes has been proposed since the 1960s: membrane transporters bind substrates on one side of the membrane and release them on the other side upon conformational rearrangements in the protein. This has been experimentally confirmed by high-resolution structures of membrane transporters in different conformations and is exemplified by the conformational change in the archaeal glutamate transporter homologue GltPh from Pyrococcus horikoshii. GltPh is a trimer in which each protomer functions independently of the others. Outward and inward facing conformations suggest transport by alternating access to either side of the membrane whereby a distinct transport domain undergoes large rotational and translational movements relative to the static trimerisation domain. It is unknown how GltPh achieves this conformational rearrangement, which occurs both in the absence and presence of substrates. We propose to integrate cutting-edge techniques in membrane structural biology to identify dynamic hotspots that drive the large conformational transitions in GltPh. We will combine insights from protein crystallography with local variations of thermodynamic stability and protein dynamics measured by hydrogen/deuterium exchange to map the structural components that allow conformational change to occur. In doing so, we will obtain new insights into how GltPh functions, shedding light on the mechanism of biomedically important glutamate transporters. We will use this model system to develop strategies that allow understanding of the molecular basis of substrate transport. The methods developed would be widely applicable to other membrane transport proteins.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2016-04-01"], "Project_ID": ["660083"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["INSTITUT CURIE", "INSTITUT CURIE"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["DrugSynergy: A data-driven systems biology approach to optimize drug combination strategies"], "Total_Cost": ["EUR 150 000"], "Country": ["France", "France"], "Project_ACR": ["DrugSynergy"], "Technology_Description": "The complex physiopathology of human chronic diseases includes networks robustness, feedback loops, and cross-talks, which may induce limited efficacy, resistance, and/or excessive toxicity of an individual drug. Learning how to combine drugs in order to improve treatment efficacy and lower undesired toxicity is a major biomedical challenge. Current strategies for drug repositioning and optimization of drug combinations have two man limitations: 1) they mostly use public data and databases, which are based on knowledge of individual drug stimuli and do not specifically analyze interactions, 2) they consider limited number of cellular outputs to analyze the response to a drug. In DrugSynergy, we will use an innovative systems biology large-scale data-driven approach to determine the interaction between two drugs at the highest possible resolution. Our computational analysis workflow has been extensively validated over the past years. It is now robust enough to be applied for the optimization of drug combinations.", "To": ["2018-02-28, ongoing project"], "Meta": [""], "Topic_s": ["ERC-PoC-2015 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2016-09-01"], "Project_ID": ["680890"], "Call_for_Proposal": ["ERC-2015-PoC"]}, -{"Partners": ["AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS"], "EU_Contribution": ["EUR 239 191,20"], "Project_Title": ["Elucidating the molecular basis of fruit resistance to desiccation: The cuticle as a key factor"], "Total_Cost": ["EUR 239 191,20"], "Country": ["Spain"], "Project_ACR": ["3F-FutureFreshFruit"], "Technology_Description": "Water stress is a key environmental factor that causes important quality and economical losses before and after fruit harvest. As water depletion is becoming increasingly problematic, improving water efficiency and tolerance of plants to dehydration is a priority of the European Union, as reflected in the societal challenge of Climate action, environment and resource efficiency. Likewise, food waste reduction is another key issue in the framework of Horizon 2020, as described in Food security and sustainable agriculture and forestry challenge. Indeed, a large proportion of fresh produce is wasted during postharvest (25-50%) of horticultural crops, which is largely caused by dehydration. Therefore, this project deals with the urgent need of understanding factors influencing water loss to develop innovative solutions geared to saving water and reducing food waste. Based on the idea that cuticular waxes are critical for limiting water loss from fruit, and thus for resisting desiccation and spoilage, we propose to uncover the structural and regulatory pathways that mediate its biosynthesis, transport and assembly in response to drought stress through a multidisciplinary approach. Thus, SEM and TEM microscopy, GC/MS, as well as up-to-date technologies, such as Laser Capture Microdissection (LCM) and RNA sequencing, will be used. Tomato and citrus fruit will be selected as model systems to address this poorly understood area of plant biochemistry, physiology and molecular biology. The availability of mutants of both fruits, as well as the application of stress-related hormones during postharvest, will allow comparative surveys to better understand the regulation of these processes. The outcomes of this proposal will represent a major advance in the understanding of the crosslink between water stress, wax metabolism and fruit biology, and will suggest strategies for enhancing shelf life, drought hardiness and fruit quality in both climacteric and non-climacteric fruit.", "To": ["2018-09-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2015-09-15"], "Project_ID": ["656127"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["INSTITUT CURIE", "INSTITUT CURIE"], "EU_Contribution": ["EUR 150 000"], "Project_Title": ["Epigenetic Profiling of Chemotherapy Efficacy"], "Total_Cost": ["EUR 150 000"], "Country": ["France", "France"], "Project_ACR": ["EPOCH28"], "Technology_Description": "The aim of this proposal is to showcase that chromatin regulators represent a novel class of biomarkers that can predict the response to individual drugs. The proof of concept will be established by validating our recent discovery of a 28-gene signature of chromatin regulators that predicts the response of 26 out of 31 patient-derived xenograft breast cancer models to docetaxel. Notably, in patients treated with docetaxel, though all are subjected to toxic side effects, less than half of them clinically benefit, and no test exists to predict response. ", "To": ["2017-04-30, closed project"], "Meta": [""], "Topic_s": ["ERC-PoC-2015 - ERC Proof of Concept Grant"], "Funding_scheme": ["ERC-POC - Proof of Concept Grant"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2015-11-01"], "Project_ID": ["678563"], "Call_for_Proposal": ["ERC-2015-PoC"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI PAVIA"], "EU_Contribution": ["EUR 180 277,20"], "Project_Title": ["Transitivity in Indo-Aryan: A diachronic syntactic data base of valence-changing categories"], "Total_Cost": ["EUR 180 277,20"], "Country": ["Italy"], "Project_ACR": ["TRIA"], "Technology_Description": "The proposed project aims at combining quantitative, corpus based research with qualitative research on language typology and language change. In particular, I plan to provide a thorough description of verbal valency and of valency-changing categories in Old Indo-Aryan along with their development in Middle and New Indo-Aryan. ", "To": ["2019-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-02-01"], "Project_ID": ["702895"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["BAY ZOLTAN ALKALMAZOTT KUTATASI KOZHASZNU NONPROFIT KFT.", "REGIONALIS INFORMACIOS ES FEJLESZTO TUDASKOZPONT KORLATOLT FELELOSSEGU TARSASAG", "HETFA KUTATOINTEZET", "TUDOMANYOS ISMERETTERJESZTO TARSULAT"], "EU_Contribution": ["EUR 207 675"], "Project_Title": ["Looking over the Horizon - horizontal priorities in research and in everyday challenges of the researchers' career!"], "Total_Cost": ["EUR 207 675"], "Country": ["Hungary", "Hungary", "Hungary", "Hungary"], "Project_ACR": ["FAWORIT 2014-2015"], "Technology_Description": "Looking over the Horizon - horizontal priorities in research and in everyday challenges of the researchers' career! The main objective of \u201cFAWORIT 2014-2015\u201d is to overcome the prevailing stereotypes about researchers and contribute to the enhancement of their public recognition through aspects of innovation, gender, mobility, international research and lifelong learning. We address the future generation and show the attractiveness of research career \u2013 with a special awareness campaign with developing \u201eSciMotion\u201d with our industrial and school partners. We focus on the target group from the age of 5 to 24, but we aim to address all age groups with attractive programmes. The series of events at 20 locations will focus on the Researcher through his/her career and the lively experiences of scientific life. The public will be \u201cedutained\u201d during the Nights: scientific presentations will be mixed with entertaining elements. There is going to be e.g. an \u201eIQ obstacle race\u201d, an exhibition of researchers\u2019 hobbies, a laser show and HiTech Pubs. The target audience can thus discover that the life of the researcher is fascinating, cool and attractive. Our objective is to have around 20,000 visitors at the events, but a multiple of that number (around 500,000) will see, hear or read about the Nights. We are planning to raise awareness of the European engagement in R&D&I with the active participation of MC Fellows. In the European Corners and at each venue related programmes of the European Union and the Marie Curie Actions will be visible. The structure of the consortium (stakeholders from academia and industry, from non-profit and for-profit organizations, with the contributing participation of schools, a cluster, a multinational company and a media partner), the elaborated concept/workplan and the involvement of strategic media partners will guarantee the success of the project. We are also keen on to participate in the celebration of the10th anniversary of Researchers\u2019 Night.", "To": ["2015-11-30, closed project |"], "Meta": [""], "Topic_s": ["MSCA-NIGHT-2014 - European Researchers' Night (NIGHT)"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Hungary"], "Activity": ["Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other"], "From": ["2014-05-01"], "Project_ID": ["633281"], "Call_for_Proposal": ["H2020-MSCA-NIGHT-2014"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET", "University of Calgary"], "EU_Contribution": ["EUR 263 719,80"], "Project_Title": ["VIsual representations of VIew Relations to support effective data analysis on large and high-resolution displays"], "Total_Cost": ["EUR 263 719,80"], "Country": ["Denmark", "Canada"], "Project_ACR": ["VIVIR"], "Technology_Description": "In VIVIR, I will conduct state-of-the-art research on supporting collaborative face-to-face data analysis. This is motivated by the increasing need for interdisciplinary teams to collaborate on understanding and analysing data. Additionally, as the scale and complexity of data increase, so does the demand for data-based insights and decision-making. My approach is to empower people who are working with large and complex data, by letting them lay out as many visualization views (in the following, denoted views) as necessary on large displays, and creating specialized meta-visualizations to show relations between these views. These meta-visualizations will allow team workers to be aware of each other\u2019s work and the changing view- and data-relationships as they work. While the potential of view meta-visualizations has been acknowledged , there are currently only a few frequently used and considered essential examples of such meta-visualizations. These might show that data in two views are compared in a third view, or that a view shows a subset of the data shown in another view. Most importantly, there has been no thorough exploration into the power and potential of meta-visualization support for data-driven decision-making. To understand the potential impact of meta-visualizations on data analysis, we need to take a structured approach, to formalize these possibilities, which will improve our abilities to support knowledge worker teams as they face the challenges of analyzing increasingly complex data.", "To": ["2020-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["753816"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI PALERMO", "THE UNIVERSITY OF NOTTINGHAM", "INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE", "UNIVERSITA DEGLI STUDI DI PERUGIA", "BENAKI PHYTOPATHOLOGICAL INSTITUTE", "UNIVERSITE DE MONTREAL", "Agriculture and Agri-Food Canada"], "EU_Contribution": ["EUR 238 500"], "Project_Title": ["Impact of invasive alien true bug species in native tropich webs"], "Total_Cost": ["EUR 252 000"], "Country": ["Italy", "United Kingdom", "France", "Italy", "Greece", "Canada", "Canada"], "Project_ACR": ["INVASIoN"], "Technology_Description": "Insects can be accidentally introduced into non-native ecosystems by humans, or expand their geographical range toward the poles as a consequence of global warming. As they invade new environments, exotic species interact with local species, modifying the structure of local food webs. New associations arising from with biological invasions can impact the strength of existing links with effects cascading through trophic levels. When invasive species are herbivores that can attack economically important crops, they can cause serious economic losses. For example, recent invasion of the brown marmorated stink bug (BMSB) (Halyomorpha halys) in Europe and North America has the potential to interfere with local trophic webs and poses a serious threat to several agro-ecosystems. ", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2016-03-01"], "Project_ID": ["690952"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["ANGLIA RUSKIN UNIVERSITY HIGHER EDUCATION CORPORATION"], "EU_Contribution": ["EUR 97 727,40"], "Project_Title": ["Design of a serious game for cars to help increase driver skills and lower fuel consumption"], "Total_Cost": ["EUR 97 727,40"], "Country": ["United Kingdom"], "Project_ACR": ["Safe and Sound Drive"], "Technology_Description": "New in-vehicle information systems and advanced driver assistance systems are currently being introduced in cars in order to help driving safely and energy efficiently. These systems help the driver to pay attention to critical events (e.g. collision warnings and blind spot information systems) or deliver important information (e.g. speed limits and navigation instructions). However, safety and environmental impact are most of all dependent on the behaviour and attitude of the driver. This proposal concerns the design of a serious game for cars that will help drivers to increase eco-driving skills, lower fuel consumption and encourage safe and environmentally friendly approaches to driving. Through his research, Dr Arne Nyk\u00e4nen has developed successful methods and procedures for efficient product sound design, already implemented at Volvo Cars and Scania. Anglia Ruskin University has leading expertise on creative and user-centred design, serious gaming, mobile applications and sound design for theatre and film. Combining this expertise enables the introduction of sound based serious gaming in cars. This provides a successful way to increase driving safety and decrease environmental impact of cars, by not only informing and warning the driver, but also changing attitudes and behaviour. The major outcomes of the project will be a demonstrator of a serious game implemented in a car, a mobile app publicly available for download, demonstrations at science centres in the UK and Sweden, 3 journal papers, participation in 4 conferences, and a new European expert network with partners from academia as well as car, game and audio engineering industry.", "To": ["2016-08-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["657233"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Decoding neural circuits controlling sleep drive and sedation"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["DNCSS"], "Technology_Description": "Sleep and anaesthesia are both commonplace states that involve reversible loss of consciousness. However, the precise regulatory mechanisms underlying both still remain elusive, particularly at the circuitry level. Previous studies suggest that sleep is homeostatically regulated and it has been proposed that the interaction between circadian rhythm and intrinsic sleep drive determines sleep status. Although much efforts have been made, the sleep field still lacks clarity regarding the nature of the \u201csleep drive\u201d as well as how it modulates sleep homeostasis. My host lab recently revealed that neuronal ensembles in the PO area, particularly in the lateral PO (LPO) area, a small region at the base of the brain that contains a mixture of sleep-active, wake-active, and temperature-sensitive neurons, are selectively activated during recovery sleep and drug-induced sedation. These results indicate that the LPO neurons are able to sense the sleep drive. In this proposal my goal is to identify LPO associated functional connectivity encoding sleep drive and sedation. By combining TetTagging functional ensembles of neurons with in vitro and in vivo optogenetics, electrophysiology and imaging techniques in mouse, I aim to 1) evaluate alterations of excitatory/inhibitory inputs onto the defined LPO neurons during prolonged wakefulness and sedation; 2) identify the origin of inputs onto the defined LPO neurons; 3) tdetermine the effects of altered connectivity involving active LPO neurons on sleep and sedation status in vivo. The results of the proposed research will provide novel insights into the regulatory mechanisms underlying sedation and the homeostatic drive of sleep.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["753548"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ELVESYS SAS"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["A microfluidic chip for automating three-dimensional cell culture for personalized medicine"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["TrueCell"], "Technology_Description": "A paradigm shift in health-care towards personalized medicine is slowly under way to tailor treatments to each unique individual\u2019s needs. A key avenue for developing this field consists in recreating in vitro models of specific body parts with cells. In particular, cells need to be placed in three-dimensions (3D) to truly recapitulate their normal environment in the body; yet current commercial assays only facilitate culture of cells in two-dimensions, which causes cells to behave very differently thus distorting the results. Microfluidic technology is ripe for facilitating this transition, but does not offer any tool to facilitate the first essential step that consists in embedding cells in gels so that they evolve in 3D inside the gel. To address this need, we propose a novel microfluidic platform that automates cell mixing with biological gels, that overcomes the challenge of mixing liquids with such different viscosities (i.e. gel and cells in liquid), and offers precise temperature control to regulate the gel formation process. This novel tool will automate a tedious procedure that is normally done manually in the lab, which will accelerate the protocol and encourage a wider practice of 3D cell culture, and guarantee the reproducibility of the gel formation around the cells. This project will enable both I and a start-up to acquire new skills in a cutting-edge field, thus driving European innovation. I will gain new expertise in becoming an independent entrepreneur and in fabricating microfluidic tools, which will complement my pre-existing deep knowledge of biological microfluidic applications. This will enable me to transition from academia to industry, from the USA to Europe, and commercialize on my own the many ideas I have been developing over my extensive career in academic research, while Elvesys who wants to enter the growing field of microfluidic cell culture, will gain an expert in 3D cell culture trained in a world-renowned academic laboratory.", "To": ["2020-01-07, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-SE - Society and Enterprise panel"], "Coordinated_in": ["France"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-01-08"], "Project_ID": ["753785"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["SARMAP SA"], "EU_Contribution": ["EUR 175 419,60"], "Project_Title": ["SaTEllyte synthetic Aperture radar interferometry to model Dam stabilitY"], "Total_Cost": ["EUR 175 419,60"], "Country": ["Switzerland"], "Project_ACR": ["STEADY"], "Technology_Description": "Analyses of surface deformation can help to define the evolution of areas, structures and infrastructures menaced by hazardous phenomena. To this end, space-borne Synthetic Aperture Radar (SAR) data provides direct measures of surface movements. Specific techniques to handle SAR data have been recently applied to monitor not only natural hazardous phenomena, such as earthquakes, subsidence and landslides, but even structural health of buildings and infrastructure. The large spread of these techniques is supported by the non-invasiveness of radar signals, the possibility to cover vast areas and the availability of a large database of data acquired since the \u201890s, despite they do not give any indication about the triggering factors and the strain source or the tensile condition of a structure. STEADY Project (SaTEllyte synthetic Aperture radar interferometry to model Dam stability) is aimed to use SAR data to monitor dam structural health and, even more, to apply an innovative approach, exploiting deformation fields as a starting point to re-create a simplified analytical model, providing preliminary hints about the stress-strain status of the dam in a short time if compared with traditional finite element models. The relevance of this process emerges when environmental or logistic conditions do not allow to monitor dams through traditional geodetic and numerical techniques. In such cases, results obtained from SAR data combined with an analytical model constitute a reliable diagnostic tool of dam structural health to avoid any extraordinary failure that may lead to loss of lives. The method will be tested on an emblematic real case, the Mosul dam, facing the following goals: (i) analysis of satellite SAR data available over the area, (ii) identification of an analytical model to reproduce dam deformation behaviour and tensile condition, (iii) implementation of a semi-automatic tool to perform numerical simulations, applicable to further cases.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-SE - Society and Enterprise panel"], "Coordinated_in": ["Switzerland"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-05-01"], "Project_ID": ["752363"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KING'S COLLEGE LONDON"], "EU_Contribution": ["EUR 251 857,80"], "Project_Title": ["Investigating the role of OPN-CD44 in mechanosensitive tumour invasion using biomimetic models"], "Total_Cost": ["EUR 251 857,80"], "Country": ["United Kingdom"], "Project_ACR": ["OPN-Can"], "Technology_Description": "New fields are rapidly emerging that provide exciting and unforeseen opportunities to target disease. This is especially relevant for difficult-to-treat tumours where, despite decades of promising research, successful clinical translation of therapeutic options remains intractable. The interrelated fields of mechanobiology and biomimetic engineered disease models have come to the fore in the last decade1\u20133 and provide a range of opportunities to investigate therapeutic modalities4. These fields have implications for cancer research in three major aspects: 1) dissection of the cell biology governing microenvironmental sensing; 2) development of biomimetic platforms that enhance both the relevance (accuracy) of experimental models and our understanding of tumour biology, especially at the level of microenvironment and cell signalling; and 3) creation of analysis tools to quantify cell sensing. In this MSCA Global Fellowship, I propose a formative advanced research training period at one of the world\u2019s leading institutions of cell and molecular biology and bioengineering (UCB) to learn and apply state-of-the-art biomimetic platforms for a novel tumour biology research project investigating osteopontin(OPN)-CD44 in mechanosensitive glioblastoma invasion. This interdisciplinary collaboration will match the expertise of UCB in biomimetic tumour invasion modelling of the biomechanical and biochemical properties of glioblastoma with my expertise in matricellular biology developed through my prior postdoctoral studies of osteopontin in liver disease. On my return to Europe at KCL, this will provide a springboard to establish an innovative independent research program in promising and underinvestigated tumour biology. I will transfer the knowledge learned at UCB to establish to investigate hepatocellular carcinoma invasion with biomimetic models. This work will ultimately benefit the development of anti-invasive adjuvant therapies.", "To": ["2020-09-03, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-04"], "Project_ID": ["752097"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF GLASGOW"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Recombination-derived replication in the eukaryotic microbe Leishmania: a genome-wide process?"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["RECREPEMLE"], "Technology_Description": "In any organism, the need to reproduce is paramount, with genome replication being the earliest step in the process. The machinery and mechanisms of DNA replication are widely conserved, with initiation occurring at defined bi-directional DNA synthesis sites termed origins. Though origins may not be conserved DNA sequences, they are defined through binding conserved replication initiator factors. In some circumstances, such as after DNA damage or origin deletion, origin-independent replication can be observed in cellular organisms and can be driven by recombination. However, origin-independent replication is not normally considered to be a genome-wide, central reaction of genome replication. Very recently, genome-wide mapping of DNA replication initiation in two species of the kinetoplastid parasite Leishmania revealed only a single locus-specific origin per chromosome. Analyses of Leishmania S phase length and DNA synthesis speed suggest that a single origin-based strategy is insufficient for complete genome duplication, indicating replication in these eukaryotic microbes relies on origin-independent initiation to support origin-directed initiation. In this proposal, I will test the hypothesis that stochastic origin-independent DNA synthesis initiation events occur throughout the Leishmania genome due to homologous recombination acting on DNA lesions. If correct, this work will reveal the first example of a cellular organism that uses origin-independent replication as a core feature of genome duplication. The genome-wide use of recombination-driven replication would alter our view of DNA replication evolution and would explain the remarkable genome plasticity of Leishmania, with implications for how the parasite adapts genome structure and gene expression in the face of changing environments. Such adaptive change is seen during acquisition of resistance to anti-leishmanial drugs, and so this work will provide insight into the use and development of therapies.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["750259"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["GUGER TECHNOLOGIES OG"], "EU_Contribution": ["EUR 178 156,80"], "Project_Title": ["Movement restoration with Adaptive EEG And Immersive Neurofeedback"], "Total_Cost": ["EUR 178 156,80"], "Country": ["Austria"], "Project_ACR": ["MoveAGAIN"], "Technology_Description": "Despite very extensive efforts to help millions of people in the EU alone who seek therapy to improve motor function after a stroke, most stroke patients are left with lifelong motor disability. Recent work from our group and others has shown that new methods and devices that can noninvasively monitor and stimulate brain activity could substantially improve recovery. EEG data collected from portable electrode caps can detect each patient\u2019s motor imagery and thereby influence multimodal feedback in real-time. This feedback may include virtual reality avatars, rewarding music or tones, functional electrical stimulation, and potentially even magnetic or electrical stimulation of motor areas of the cortex. This promising new research direction requires extensive collaboration across disciplines and sectors, and experienced researchers (ERs) with relevant experience. The MoveAGAIN project will explore new classifiers, experimental paradigms, and software in tandem with an existing commercial system to create a new system that will be used to collect data with stroke patients in two real-world settings. We will analyze the resulting data to develop new knowledge and contribute to improved tools that therapists and physicians can use with patients. MoveAGAIN includes extensive dissemination and communication activities to convey our project results to numerous audiences. The varied training activities will supplement the ER\u2019s training-by-research to help prepare him for a high-impact career working across industrial, academic, and medical sectors.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-SE - Society and Enterprise panel"], "Coordinated_in": ["Austria"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2018-01-01"], "Project_ID": ["752620"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF SHEFFIELD", "INSTITUT CURIE", "TECHNISCHE UNIVERSITAET DRESDEN", "UNIVERSITY COLLEGE LONDON", "THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE", "UNIVERSITA DEGLI STUDI DI PADOVA", "FUNDACION CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III", "JPK INSTRUMENTS AG", "BIONCOTECH THERAPEUTICS SL", "MIMETAS BV"], "EU_Contribution": ["EUR 3 911 897,16"], "Project_Title": ["Biochemical and mechanochemical mechanisms in polarized cells"], "Total_Cost": ["EUR 3 911 897,16"], "Country": ["United Kingdom", "France", "Germany", "United Kingdom", "United Kingdom", "Italy", "Spain", "Germany", "Spain", "Netherlands"], "Project_ACR": ["BIOPOL"], "Technology_Description": "BIOPOL is an interdisciplinary European training network at the interface of cell biology, physics and engineering. BIOPOL aims specifically at the understanding of fundamental mechanochemical principles guiding cellular behaviour and function and their relevance to human disease. A new supra-disciplinary research field is emerging bringing together the fields of molecular cell biology, physics and engineering aiming at an in depth understanding of fundamental cellular mechanochemical principles. BIOPOL combines exactly this required expertise in one joint training program for young researchers. BIOPOL has assembled a unique multidisciplinary consortium bringing together top scientists from the fields of molecular/developmental cell biology, membrane physics, engineering as well as specialists from the private sector. The scientific objectives focus on understanding of fundamental mechanisms of cellular mechanosensing in health and disease, the role of external forces in cell division and mechanochemical regulation of cell polarity including tissue formation. Finally, part of BIOPOL\u00b4s research program is the further development of cutting edge technologies like advanced atomic force microscopy, novel photonic tools like optical stretcher or innovative organ on a chip technology, exploiting physical cellular properties. BIOPOL\u00b4s collaborative cutting edge research program is integral part of its training program provided to early stage researcher and is further translated into seven state of the art experimental training stations representing the consortiums expertise. In addition, BIOPOL has developed a 3 years modular curriculum including workshops, summerschools, Business plan competitions and conferences with a specific agenda of transferable skill training elements highly relevant for scientific communication, translational research and in particular entrepreneurship.", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["641639"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["OZYEGIN UNIVERSITESI"], "EU_Contribution": ["EUR 157 845,60"], "Project_Title": ["A Collaborative Mobile Robot Arm that can Learn Impedance Critical Tasks from Humans"], "Total_Cost": ["EUR 157 845,60"], "Country": ["Turkey"], "Project_ACR": ["CoMRAde"], "Technology_Description": "The aim of the proposed research is to develop a mobile manipulator that can effectively learn impedance critical tasks by means of physical interactions with a human, and acquire human\u2019s abilities via human-to-robot skill transfer for subsequent autonomous task execution. In a factory environment, execution of such tasks, e.g., drilling, screwing, are frequently encountered and can be easily accomplished by human workers. Nevertheless, automating these tasks with robots require expert robotics engineering knowledge, robot-specific arrangements in the factory, and exact model of the environment. Through the integration of human-to-robot skill transfer techniques, these monotonous tasks can be autonomously handled by a mobile manipulator so that human workers can focus on more complicated tasks. To this end, this project aims to develop required technologies to create such a system that can be actively used in a real factory environment for actual scenarios. With the successful completion of the project, a crucial building block will be built for human-centered robotic automation, which is of importance in keeping the manufacturing jobs in EU.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Turkey"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["753219"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ASOCIACION BC3 BASQUE CENTRE FOR CLIMATE CHANGE - KLIMA ALDAKETA IKERGAI", "UNIVERSITY OF OTAGO"], "EU_Contribution": ["EUR 233 276,40"], "Project_Title": ["SAfeguarding Biodiversity and Ecosystem seRvices by integrating CULTURAL values in freshwater management: learning from M\u0101ori"], "Total_Cost": ["EUR 233 276,40"], "Country": ["Spain", "New Zealand"], "Project_ACR": ["SABER CULTURAL"], "Technology_Description": "Freshwater ecosystems are essential to people\u00b4s economic, cultural and social wellbeing, yet are still one of the most seriously threatened ecosystems on the planet. This conflict is reflected in political regulations that ask to halt the loss of, restore and safeguard freshwaters, their biodiversity and the ecosystem services they provide. Ecosystem-Based Management (EBM), a holistic approach advocated to help doing so, involves an overarching regulatory framework and local solutions with trade-offs and compromises - factors that make decision processes complex and easily co-opted. In SABER CULTURAL, we use a well-known participatory decision support framework (MCA) to tackle two major challenges in freshwater EBM: 1) including cultural values that build a conceptual link between natural resources/biodiversity and local knowledge, besides traditionally considered ecological and socio-economic ones, and 2) accounting for uncertainty. MCA is selected because it is i) transparent, ii) allows for the whole range of stakeholder values to be quantified and accounted for, iii) can be used to robustly test outcomes of different management scenarios, and iv) can ultimately be used to prioritise cost-effective management actions with collective buy in. To forecast ecosystem services flow under different management alternatives, MCA is coupled with a novel modelling approach (ARIES). We test the MCA-ARIES framework in New Zealand, where cultural M\u0101ori-values play a prominent role in freshwater management, and transfer the flow models to the river basin scale to inform existing management plans and policies in Europe. With SABER CULTURAL we establish new standards for freshwater management in New Zealand, create knowledge that helps reaching EU biodiversity and environment targets and add value to the dialogue among EU policy sectors. Additionally, SABER CULTURAL provides a unique opportunity to gain the skills I need to become an established, independent researcher in Europe.", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["748625"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["STICHTING VU"], "EU_Contribution": ["EUR 165 598,80"], "Project_Title": ["Who Should Have a Say? Preferences for Unequal Representation"], "Total_Cost": ["EUR 165 598,80"], "Country": ["Netherlands"], "Project_ACR": ["UNREP"], "Technology_Description": "Equal representation is at the core of representative democracy, but are citizens actually in favour of it? There are good reasons to think that citizens may take a variety of stances toward unequal representation (i.e. differential group influence over policy) particularly when it comes to groups that elicit strong emotional reactions (e.g. racialised minorities). Citizens may think that policy-affected groups deserve extra input (due to affectedness), less input (due to bias), or the same amount of input as everyone else. However, it is impossible to say anything meaningful about these attitudes since we know almost nothing about them. This lack of knowledge is a serious shortcoming with real-world implications: these preferences shape politics and, by extension, the functioning of representative democracies. My proposed study is thus relevant not only for recent debates in political science over both the extent and origins of unequal representation, but also for contemporary politics \u2013 with its surging populist claims that certain groups have excessive influence over policy.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["750556"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITA CA' FOSCARI VENEZIA"], "EU_Contribution": ["EUR 244 269"], "Project_Title": ["A cultural history of comparative art practices and receptions in Cold War Europe (1945-1991)"], "Total_Cost": ["EUR 244 269"], "Country": ["Italy"], "Project_ACR": ["GYSIART"], "Technology_Description": "Cold War studies tend to emphasize dual narratives, mostly investigated as actions that are dictated from above by State policies or as cultural relations in an international context. Starting from my previous studies on bilateral art relations in the second half of 20th century, the project is intended as a comparative survey within a polycentric and inclusive European focus area, including the two German republics, Yugoslavia, the Soviet Union and Italy. The main study cases will be provided by multilateral art encounters and the involved locations and actors, analysed as individual and collective art practices. Unique Cold War art archives and collections at the Getty Research Institute and at the Wende Museum in Los Angeles will provide key resources. In order to assess the impact of the art practices on culture and society, I intend to investigate both their critical reception in the professional art world and their popular response through the commentaries left by exhibition visitors. A crucial question is whether the European dimension has ever been considered as a common ground - be it of political, social, artistic or speculative nature - for multilateral art practices within the divided continent. Particular attention will be paid to unmet expectations and missed connections among the interested art communities. By including current Member and Associate States and Third Countries, the research is meant to contribute to inter-European comprehension and integration, as an essential premise in order to \u201cinform the reflection about present problems and help to find solutions for shaping Europe's future\u201d, as stated in the Work programme 2016-2017 of Horizon 2020. The project is conceived as a multidisciplinary research which, through training and inter-sectoral mobility in Comparative Studies, History and Art History, will have a ground-breaking impact on my future career prospects in the academic and non-academic sectors as Comparative European Art Historian.", "To": ["2021-01-07, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-08"], "Project_ID": ["750682"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE DE BRETAGNE OCCIDENTALE"], "EU_Contribution": ["EUR 264 668,40"], "Project_Title": ["Basin modes of the ocean: their role in the interannual to interdecadal climate variability"], "Total_Cost": ["EUR 264 668,40"], "Country": ["France"], "Project_ACR": ["OceanModes"], "Technology_Description": "Decadal climate predictions are a strong societal need for both EU and non-EU communities. However, mechanisms of low-frequency variability of the climate system remain unclear, preventing accurate prediction of decadal climate changes. Several mechanisms have been proposed so far and they can be sorted in three categories: ocean only, atmospheric only and coupled dynamics. My project falls in the first category, focussing on the intrinsic variability of the ocean forced by prescribed steady (or seasonally varying) atmospheric forcing. Because of the long memory of the ocean, recurrent patterns of oceanic variability, such as the oscillatory free basin modes, are the best candidates for decadal predictions of the ocean-atmosphere system. However, our current understanding of the dynamics behind basin modes is low and urgent action is needed to improve it. An important question is whether these patterns can emerge above the noise level of stochastic variability. One of my scientific hypotheses is that local baroclinic instability at high latitudes, in addition to wind-stress and surface buoyancy fluctuations, can excite robust global modes of oceanic variability. Objectives of my project consist in increasing our knowledge of oceanic basin modes and assessing their relevance to decadal climate predictions. In the first part of the project, the dependence of the global modes on external parameters, such as bathymetry, model resolution, coastlines and mean flow will be systematically studied in a step-by-step approach. In the second part, I will obtain the optimal forcing of the basin modes and its dependence on the external parameters cited above. In the third part, the basin modes will be calculated in a realistic setting of the world ocean and rationalized in the light of what have been learnt in the first two parts.", "To": ["2021-01-07, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-08"], "Project_ID": ["749924"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Novel RF Driven MRI Magnet for Imaging Enhancement"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["RF-MAFS"], "Technology_Description": "The key goals of the RF-MAFS project are: the training of the Experienced Researcher (ER) Dr. Javier Alonso-Valdesueiro, in the fast growing field of Scientific Instrumentation, where the host and partner institutions have critical knowledge and expertise and the design, development and optimisation of a new Magnetic Resonance Imaging (MRI) machine based on the concept of Radio-Frequency Magic Angle Field Spinning (RF-MAFS). The aim of the research project is to design and develop a novel type of portable MRI scanner which enhances the image resolution by applying a rotating magnetic field. This project brings together Engineering Skills, Magnetic Resonance (MR) Knowledge and Medical Imaging Insights. Therefore, it will clearly have a broad positive impact on the European Research Area (ERA). The interdisciplinary and intersectoral training program includes specific training in RF power devices, magnet design and training in transfer of knowledge from academia to industry. Then, it will enhance and broaden Dr. J. Alonso-Valdesueiro\u00b4s expertise in Applied Scientifc Instrumentation, increasing his exposure to both academia and industry. The Fellow is a talented researcher who has gained much expertise in engineering applied to NMR during his postgraduate career. This background is of great value for the optimization magnet design for medical imaging. But for further boost his career, Javier needs to gain expertise in prototype construction for scientific applications in which the University of Basque Country has a world-recognised expertise. Additionally, through the three-month secondment at University College London he will have contact with the medical image processing part of the action. Therefore, The multidisciplinary project activities including outreach activities, supervision, and complimentary course outlined in the work plan, reflect all training objectives and will assist Javier in acquiring necessary competences and reaching professional maturity.", "To": ["2019-09-03, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-04"], "Project_ID": ["750445"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CARDIFF UNIVERSITY"], "EU_Contribution": ["EUR 97 727,40"], "Project_Title": ["Innate-Like T-Cells In Sepsis (ILTIS): Implications for Early Diagnosis and Rescue of Immune Suppression."], "Total_Cost": ["EUR 97 727,40"], "Country": ["United Kingdom"], "Project_ACR": ["ILTIS"], "Technology_Description": "Research on infectious diseases has high priority for the scientific and medical communities worldwide, to tackle the alarming spread of multidrug resistant bacteria and to fight and prevent virus outbreaks. On the French island of La R\u00e9union, infections such as leptospirosis and chikungunya pose considerable threats for public health. My career aspiration is to establish myself as a clinical scientist in the field of immunology of microbial infections, especially in severe conditions such as septic shock and leptospirosis. I am also interested in deciphering the emerging role of host cell-derived factors (HSDF) in shaping the innate immune response. The immune response to pathogens and HSDF involves numerous cell types and soluble factors such as cytokines but remains ill-characterized. A better understanding of the cellular and molecular signatures in acute disease may pave the way to better and earlier diagnosis, targeted treatment and improved outcomes. ", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["747278"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI FIRENZE"], "EU_Contribution": ["EUR 244 269"], "Project_Title": ["TARGETING ENDOTHELIAL CELL AND CANCER AMOEBOID MOVEMENT TO OVERCOME RESISTANCE TO ANTI-VEGF AND ANTI-PROTEASE THERAPIES"], "Total_Cost": ["EUR 244 269"], "Country": ["Italy"], "Project_ACR": ["ENDOCAM"], "Technology_Description": "Unlike mesenchymal migration, the amoeboid motility doesn\u2019t require proteases and is an opportunistic movement of cancer cells which allows cells to glide through, rather than degrade, ECM barriers, using movements based on adaptations of the cell body. Preliminary experiments we conducted using a mixture of physiologic inhibitors of serine-proteases, metallo-proteases and cysteine-proteases, thus mimicking a physiological environment, showed no differences in vessel formation for both Endothelial Progenitor Cells (EPCs) and mature Endothelial Cells (ECs) under mesenchymal or amoeboid conditions. Thus, we hypothesized the existence of an \u201camoeboid angiogenesis\u201d. We also hypothesized that the failure of cancer treatment using synthetic metalloproteinase inhibitors (MPIs) could be ascribed to the ability of cancer and ECs to skip the attack of the MPI therapy by allowing cancer invasion and blood vessel formation using the \u201camoeboid\u201d strategy. Even the VEGFA targeting partially disregarded the expectations because of the resistance onset followed by the progression of the disease. Our preliminary experiments showed also an \u201cindifference\u201d of ECs and EPCs to VEGF stimulation under amoeboid conditions. Therefore, the aim of this project is to identify the multiple mechanisms shared by cancer cells and ECs/EPCs in the regulation of amoeboid movement, to identify common therapeutic strategies impairing vascular growth and cancer cell invasion at the same time, overcoming resistance to anti-VEGF and anti-protease therapy. The molecules identified (ephrin, protease receptors, etc.) will be used as candidates for targeted therapy through the delivery of cargo liposomes containing inhibitors of the connection of such molecules with the cortical actin cytoskeleton, in pre-clinical experiments with the perspective of a possible application to humans. We expect that this approach will give a progress in the treatment of tumors thus improving outcomes for cancer patients.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["748731"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ROYAL COLLEGE OF SURGEONS IN IRELAND"], "EU_Contribution": ["EUR 175 866"], "Project_Title": ["Polyester/Polypeptide hybrid biomaterials for biomedical scaffolds"], "Total_Cost": ["EUR 175 866"], "Country": ["Ireland"], "Project_ACR": ["EsterPep"], "Technology_Description": "Next generation bioabsorbable and biocompatible polymeric biomaterials are key for the development of new medical devices and advanced approaches in healthcare with significant impact on applicable and affordable treatments for EU citizens. EsterPep will bring together the expertise of the applicant in organo-catalytic synthesis of polyesters with the expertise of the host in synthetic polypeptides and medical applications with the objective to design a new class of poly(ester-peptide) hybrid materials fully based on natural raw materials. The marriage of both systems promises novel functional, processible biomaterials with adaptable material and degradation properties not available from the individual building blocks alone. The objective will be achieved in an interdisciplinary approach combining polymer chemistry and biomaterial science as well as the demonstration of processing feasibility into a biomedical scaffold for tissue engineering. The workpackages have been designed to balance synthetic and application work as well as offering opportinities for intersectorial contacts to benefit the applicants experience. This project is ideally suited to the MSCA-IF programme as it provides mobility and a nurturing, world-class environment for the applicant to embark on a future professional academic career. This will be achieved by developing relevant competences and skills supporting this career path combined with unique scientific training in applied biomedical and biomaterial science guided by a tailored Career Development Plan. The dissemination of research results will target professional audiences as well as communicating to the general public through outreach activities.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["748364"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KARLSRUHER INSTITUT FUER TECHNOLOGIE"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Advanced Self-sorting and Supramolecular Polymers"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["ASSP"], "Technology_Description": "The controlled formation of well organised self-assemblies within multicomponent supramolecular systems remains a challenge for modern chemistry. Herein, the aim of this project is to construct a constitutionally dynamic library containing advanced supramolecular architectures (i.e. a molecular grid, a linear helicate and a macrocycle) through the combination of orthogonal self-assembly and self-sorting, then we intend to take advantage of the dynamic and orthogonal interactions developed to synthesise doubly-dynamic main-chain and crosslinked metallo-supramolecular polymers.", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-11-01"], "Project_ID": ["749351"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE D'AIX MARSEILLE"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Structure-activity relationships of an emerging family of fungal lytic polysaccharide monooxygenases"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["ARTFUL"], "Technology_Description": "During the past century, fossil-based hydrocarbons have been the main source of energy and chemicals, but in addition to be an unsustainable resource, they have led to important environmental concerns such as rising CO2 emissions. The great challenge for our societies is to develop alternative approaches for the sustainable production of energy and materials; the bioconversion of lignocellulosic biomass is one of them. Nevertheless, the physical and chemical recalcitrance of the biomass is the main obstacle to its cost-effective conversion as huge amounts of degrading enzymes are still required. Therefore, a significant improvement in enzymatic degradation is necessary, which involves enlarging the catalytic toolbox. By doing a large scale screening of the secretomes of a substantial fungal collection, the host organisation has shed light on the first member of a new family of lytic polysaccharide mono-oxygenases (LPMOs). LPMOs have been shown to boost the efficiency of cellulases industrial cocktails, thereby greatly reducing the financial and environmental penalties associated with the use of recalcitrant polysaccharides as a feedstock and, moreover, placing LPMOs at the center of considerable research interest. The objective of the ARTFUL project is the functional and structural characterization of the representative members of the new fungal LPMO family. The 6 years\u2019 experience of the French fellow in the glycobiology field (biochemistry, enzymology, structural biology) combined with the expertise of Aix-Marseille University (France) in fungal omics form a solid basis that will be reinforce by the collaborations of experts. The quality of the hosting arrangements will maximise the training opportunities of the fellow and is suited for the two way transfer of knowledge. Acquired generated knowledge will provide a robust functional context to bioinformatic-based predictive biology as well as new enzymatic tools for subsequent industrial applications.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["748758"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CENTRE INTERNACIONAL DE METODES NUMERICS EN ENGINYERIA"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Simulation of metal Solidification in Additive Manufacturing processes"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["SimSolidAM"], "Technology_Description": "The project is aimed to the enhancement of numerical simulation tools for the Additive Manufacturing process, focusing on analysis of temperature evolution and solidification behaviour of material during the Metal Deposition process.", "To": ["2019-03-14, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-03-15"], "Project_ID": ["746250"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSIDADE DO ALGARVE"], "EU_Contribution": ["EUR 160 635,60"], "Project_Title": ["Characterizing the clinical relevance and the mechanism underlying TRIB2-mediated drug resistance to MEK inhibitiors in the context of melanoma"], "Total_Cost": ["EUR 160 635,60"], "Country": ["Portugal"], "Project_ACR": ["TRIBBLES"], "Technology_Description": "Melanoma is the most aggressive form of skin cancer resistant to all standard therapies. Currently, the established treatment of metastatic melanoma includes dacarbazine (DTIC) administration associated with response rates of between 10-20% with severe side effects during treatment. Recently, the BRAF inhibitors (vemurafenib and dabrafenib) and the MEK inhibitor (trametinib) were approved for the treatment of melanoma patients with mutated BRAF (about 50% of patients) while there are several PI3K, AKT, mTOR and MEK inhibitors being tested in clinical trials. However, the effectiveness of all these treatment modalities is limited by intrinsic or acquired resistance. The host lab has discovered a novel mechanism of resistance to a broad spectrum of drugs in clinical trials/use for melanoma therapy mediated by the kinase-like protein TRIB2. This means that TRIB2 could be used as a biomarker to select melanoma patients for specific treatment options and to develop co-treatment strategies to overcome drug resistance. This project pretends to (1) understand the mechanisms underlying TRIB2-mediated resistance to MEK inhibitors and to (2) further develop TRIB2 as a prognostic and predictive biomarker for melanoma. Ultimately, the expected results will be highly relevant for the clinic as they might allow to select melanoma patients for specific treatment options and to develop co-treatment strategies to overcome TRIB2 mediate resistance.", "To": ["2020-03-04, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Portugal"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-03-05"], "Project_ID": ["748585"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF LEEDS"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Geochemical Controls on the Ice Nucleating Efficiency of Volcanic Ash"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["INoVA"], "Technology_Description": "Ice formation in the atmosphere has a major impact on the properties and lifetime of clouds yet is one of the least well understood processes indirectly affecting the Earth\u2019s climate. Heterogeneous ice nucleation by airborne solid particles (\u2018ice nuclei\u2019) exerts a profound influence on clouds by raising the temperature at which ice can form relative to by homogeneous freezing of supercooled water droplets. Volcanic ash from explosive eruptions is increasingly recognised to be capable of acting as ice nuclei but factors determining the ash ice nucleating efficiency have yet to be elucidated. As for mineral dust from arid and semi-arid regions, physicochemical properties of the solid particles such as crystallinity, mineralogy and composition likely play a role in their ice nucleating efficiency, but this remains poorly understood and has not been systematically investigated for volcanic ash. In addition, the influence of thermochemical processes/conditions in the source magma, in the eruption plume and cloud, and in the ambient atmosphere on ash ice nucleating efficiency is not known. The proposed research will address this gap in knowledge through an experimental approach uniquely bridging volcanic geochemistry and atmospheric science, to establish the link between ash ice nucleating efficiency and its physicochemical properties and magmatic, eruptive and atmospheric history. A range of natural ash and synthetic ash, generated and treated under controlled laboratory conditions, will be studied. Experimental data will be parameterised for use in model simulations to predict regional ice nuclei concentrations based on an Icelandic eruption scenario. Collectively, the proposed research, training and knowledge transfer activities will enhance the future prospects of both the Fellow and host, while contributing to the greater benefit of society by improving understanding of the potential impacts of ash emissions from explosive eruptions on the atmosphere and on climate.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["746695"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ISTITUTO NAZIONALE DI FISICA NUCLEARE"], "EU_Contribution": ["EUR 180 277,20"], "Project_Title": ["High Precision PDFs for the precision Era at the Large Hadron Collider"], "Total_Cost": ["EUR 180 277,20"], "Country": ["Italy"], "Project_ACR": ["HiPPiE_at_LHC"], "Technology_Description": "High precision is the next frontier for the Large Hadron Collider (LHC). It requires accurate and precise theoretical predictions. The goal of this project is twofold: establish a statistically solid framework for estimating the uncertainty on theoretical predictions, and producing more precise higher-order parton distribution functions (PDFs).", "To": ["2019-10-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations"], "From": ["2017-11-01"], "Project_ID": ["746159"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF LEEDS", "UNIVERSITY OF LEEDS"], "EU_Contribution": ["EUR 1 258 250"], "Project_Title": ["Seizing the Hybrid Areas of work by Re-presenting self-Employment"], "Total_Cost": ["EUR 1 258 250"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["SHARE"], "Technology_Description": "SHARE is a transdisciplinary and multi-method study of the work arrangements which destabilize the dichotomies between standard and non-standard work and between self-employment and dependent employment. More specifically, it will research solo self-employment, namely self-employment without employees. This is a growing contractual category in Europe which comprises very different subjects, often disguised by statistics and difficult to represent by unions: from independent professionals to \u2018fake self-employed\u2019 workers legally self-employed but in fact wholly dependent on the company. Therefore, I introduce the concept of \u2018hybrid areas of work\u2019 to refer to the co-existence of features usually attributed to categories traditionally kept sharply distinct.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["715950"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["AALTO-KORKEAKOULUSAATIO"], "EU_Contribution": ["EUR 179 325,60"], "Project_Title": ["Cooper pair splitter based on Dirac materials"], "Total_Cost": ["EUR 179 325,60"], "Country": ["Finland"], "Project_ACR": ["DiracEntangler"], "Technology_Description": "Cooper pairs splitters (CPS) are promising candidate devices for solid-state sources of spin entanglement; a long-sought goal of outstanding impact in the development of quantum technologies. Recent experiments have reported high splitting efficiencies but measurements can not resolve individual splitting events and are limited to time-averaged current and noise. ", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Finland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["743884"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAT AUTONOMA DE BARCELONA"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Labor Market Segmentation and Political Participation"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["LABOREP"], "Technology_Description": "Labor market segmentation is a defining feature of advanced industrial democracies. Workers experience different levels of labor risks and protections, with those in secure employment enjoying statutory entitlements and social benefits while the low-paid, insecurely employed, underemployed and long-term unemployed do not. During the recent economic recession, the process of labor market segmentation has hastened, reaching unprecedented levels of differentiated labor risks. Apart from the consequences of segmentation on social and economic inclusiveness and on long-term economic growth potential, segmentation has important but neglected implications for political inclusion and representation. LABOREP aims to fill this gap by examining how labor market inequalities shape political mobilization.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["742991"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["WAGENINGEN UNIVERSITY"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["The role of necrotrophic effectors in the ability of Botrytis and Monilinia species to infect host plants"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["NECROFUNGI"], "Technology_Description": "Botrytis cinerea and Monilinia fructicola are both devastating pathogens that can cause decay in a broad range of hosts during pre and postharvest handling. Despite the current use of chemical fungicides, both fungal pathogens are still responsible of important economic losses worldwide. The knowledge of pathogen virulence mechanisms is an important step to guide the search for new control strategies alternative to the fungicides currently in use. Crucially, the genome sequences of both B. cinerea and M. fructicola can be exploited to identify genes and proteins that determine their ability to infect host plants. By applying molecular and bioinformatic analysis, NECROFUNGI aims to identify genes that encode necrotrophic effector proteins which only kill their specific host, but do not affect other plant species. The identification of genes responsible for disease will lead the way towards new strategies to control plant diseases based on the development of new classes of chemicals that are not directly toxic to fungi and to design more efficient breeding strategies. Wageningen University has an extraordinary resource to carry out this research. The host will train Dr. Vilanova in molecular and bioinformatic techniques in the study of the B. cinerea and M. fructicola genomes, providing the necessary skills for her to establish a similar facility in her home country in the study of M. fructicola where none currently exists. In turn, the fellow will bring specific expertise in postharvest fruit-pathogen interactions, not currently available at the host institution. The multidisciplinary perspective adopted, combining fruit-pathology, comparative genomics, molecular biology and bioinformatics will build the necessary information to control these two devastating pathogens by effector-based technologies that would provide a great economic benefit for EU agriculture.", "To": ["2020-02-29, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["741964"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["EURECOM", "EURECOM"], "EU_Contribution": ["EUR 1 978 777,83"], "Project_Title": ["Theoretical Foundations of Memory Micro-Insertions in Wireless Communications"], "Total_Cost": ["EUR 1 978 777,83"], "Country": ["France", "France"], "Project_ACR": ["DUALITY"], "Technology_Description": "We propose to develop the theoretical foundations of transforming memory into data rates, and to explore their practical ramifications in wireless communication networks.", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["725929"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["KING'S COLLEGE LONDON"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Quantitative brain network biomarkers for patient-specific diagnostics in idiopathic generalized epilepsy"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["NETBIO-GE"], "Technology_Description": "Epilepsies are common and highly disabling diseases characterised by recurrent seizures. They constitute a relevant health problem: ~2 million adults suffer from active epilepsy in Europe, leading to significant direct and indirect costs (estimated to be ~14 billion euro (2010)). The scientific objective of this fellowship, to be carried out at the Division of Neuroscience at King's College London and the Centre of Predictive Modelling in Health Care of the University of Exeter, is to develop a novel type of diagnostic biomarker for idiopathic generalised epilepsies (IGE), an important group of syndromes that affects 25-30% of patients, particularly young adults. This will be achieved by conducting a cross-sectional case-control study that will use advanced quantitative neuroimaging techniques to measure alterations of brain network connections in IGE patients and healthy controls, and machine-learning algorithms to (1) classify patients with different seizure types according to these alterations, (2) predict their seizure risk, as assessed with long-term electroencephalography (EEG), and (3) model the effect of network disruption on brain dynamics, using computational modelling. The educational objective is to equip the fellow with the skills needed to become an independent clinical scientist in epileptology. This will be achieved through a comprehensive clinical and scientific teaching programme that will include: (1) part-time participation in clinical rounds and clinical long-term EEG monitoring of complex epilepsy, (2) training in the neuroanatomy and quantitative measurement of white matter connections of the human brain,(3) training in computational neuroscience, and (4) courses in scientific writing and project management. This programme is expected to broaden and diversify the fellow's skills, strengthen the ties between the cooperating research centers and yield novel insights that might help improve clinical management of a highly relevant disease group.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["750884"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["HEINRICH-HEINE-UNIVERSITAET DUESSELDORF", "HEINRICH-HEINE-UNIVERSITAET DUESSELDORF"], "EU_Contribution": ["EUR 1 995 890"], "Project_Title": ["Tree rewriting grammars and the syntax-semantics interface:From grammar development to semantic parsing"], "Total_Cost": ["EUR 1 995 890"], "Country": ["Germany", "Germany"], "Project_ACR": ["TreeGraSP"], "Technology_Description": "The increasing amount of data available in our digital society is both a chance and a challenge for natural language processing. On the one hand, we have better possibilities than ever to extract and process meaning from language data, and recent techniques, in particular deep learning methods, have achieved impressive results. On the other hand, linguistic research has a much broader empirical basis and can aim at rich quantitative models of language. Unfortunately, theory and application interact too little in these areas of meaning extraction and grammar theory. Current semantic processing techniques do not sufficiently capture the complex structure of language while grammatical theory does not sufficiently incorporate data-driven insights about language. ", "To": ["2022-06-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-07-01"], "Project_ID": ["724411"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Suppresion of adaptive immunity by the Salmonella effector SteD"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SupaSteD"], "Technology_Description": "In this project, I propose to characterize the influence of SteD, an effector of a globally important bacterial pathogen Salmonella enterica, on T cell development, and its potential therapeutic application. In the mouse model of S. enterica infection, the onset of the specific immune responses is delayed significantly in comparison to other bacterial pathogens. Recent work by the group of Prof. Holden, who is the supervisor of this project, a world leader in the field of Salmonella pathogenesis and the Director of the MRC Centre for Molecular Bacteriology and Infection (MRC-CMBI) at Imperial College London, identified SteD, an effector of the Type III Secretion System (T3SS) encoded by Salmonella pathogenicity island 2 (SPI-2), as the first example of a virulence factor that reduces surface-localised mature Major Histocompatibility Complex class II (MHCII) levels in Dendritic Cells. In addition, I have found an increased activation of T cells following infection of C57BL/6 mice with S. enterica serovar Typhimurium (STm) \u0394steD mutant in comparison to wild-type STm, thereby showing that SteD is an important modulator of adaptive immunity in vivo. SteD and/or its gene have a high chance of having therapeutic application. I also have obtained preliminary evidence indicating that SteD has additional functions in the manipulation of antigen-presenting cells. Therefore, I propose to use both the acute and chronic mouse models of Salmonella infection to further characterize the influence of SteD on T cell development. Furthermore, I will investigate the mechanistic and physiological significance of natural variation in the amino acid sequence of SteD among a broad range of S. enterica serovars, including the typhoid fever-causing human-adapted serovars Typhi and Paratyphi. Finally, I will explore the possible use of SteD in new formulations of DNA vaccines. These studies will provide important knowledge for the clinical application of this newly described T3SS effector.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["747392"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Multifocal structured illumination optoacoustic microscopy"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["MSIOAM"], "Technology_Description": "Optoacoustic imaging is a highly scalable and versatile method that can be used for optical resolution microscopy (OR-OAM) at superficial depth yet can be adapted for tomographic imaging with ultrasonic resolution at centimeter penetration scale. However, the imaging speed of OR-OAM is slow as far as concerned with acquisition of volumetric data, which greatly restricts its usage in applications involving dynamic biological processes.", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Research Organisations"], "From": ["2018-02-01"], "Project_ID": ["746430"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CENTRO DE ESTUDOS SOCIAIS"], "EU_Contribution": ["EUR 160 635,60"], "Project_Title": ["Alternative Grassroots Organizations as a Response to Austerity: perspectives from Southern Europe"], "Total_Cost": ["EUR 160 635,60"], "Country": ["Portugal"], "Project_ACR": ["AGORA"], "Technology_Description": "In recent years the global financial crisis and the consequent austerity measures have triggered protest movements all over the world. In Southern Europe there has been a strong wave of mobilizations directed to defend public welfare provision. These anti-austerity movements have been characterized by a call for social justice framed in solidarity and inclusion, against the perception of a reduced capacity by the state of addressing citizens\u2019 needs. This low level of trust in institutional politics has triggered the creation of alternative spaces of deliberative and participatory democracy, directed to experiment with different political expressions. A crucial question is whether and how this claim for different forms of democracy has been translated by social movements into organizational forms that bring increased democracy also into the economic sphere. In order to address this still underinvestigated issue, AGORA focuses on those entrepreneurial activities that originate from the civil society, in this specific case as a direct expression of anti-austerity movements, that are characterized by the prevalence of social objectives over profit maximization.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Portugal"], "Activity": ["Research Organisations"], "From": ["2017-06-01"], "Project_ID": ["747082"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Hybrid Imaging of PET and PrOmpt gamma for preCision RAnge- and biological- guidance in proton ThErapy"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["HIPPOCRATE"], "Technology_Description": "Proton therapy is rapidly being established in the EU as a promising external beam tumour therapy modality offering an increased tumour-dose conformity with better sparing of critical organs and healthy tissue compared to conventional photon therapy. However, full exploitation of its clinical potential is still hampered by non-negligible uncertainties during the treatment planning and delivery, posing the urgent demand of novel real-time techniques for in vivo verification of the proton beam range. To this aim, the objective of this project proposal HIPPOCRATE (Hybrid Imaging of PET and PrOmpt gamma for preCision RAnge- and biological- guidance in proton ThErapy) is to explore the optimal design and clinical potential of an innovative hybrid medical imaging approach that goes well beyond the state of the art, by combining real-time range verification from energetic prompt gammas with Positron-Emission-Tomography (PET) imaging of irradiation-induced or externally injected tracers, to promote biological- and dose- guidance for personalized, high-precision proton therapy. By improving the quality of the rapidly emerging proton therapy modality, this project will promote longer and healthier lives for cancer patients, with a high societal impact on the EU. Moreover, HIPPOCRATE can potentially go beyond the boundaries of medical imaging in proton therapy, by enabling high quality imaging of a whole new range of promising unconventional radionuclides for diagnostic nuclear medicine imaging, as well as opening the perspective of biological image guidance at the radiotherapy treatment site, independent of the primary radiation quality.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["750689"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["REGIONALIS INFORMACIOS ES FEJLESZTO TUDASKOZPONT KORLATOLT FELELOSSEGU TARSASAG", "BAY ZOLTAN ALKALMAZOTT KUTATASI KOZHASZNU NONPROFIT KFT.", "HETFA KUTATOINTEZET", "TUDOMANYOS ISMERETTERJESZTO TARSULAT"], "EU_Contribution": ["EUR 207 675"], "Project_Title": ["Fascinating World of Researchers in the Age of Technology 2016/2017 - The New Generation of Innovators"], "Total_Cost": ["EUR 207 675"], "Country": ["Hungary", "Hungary", "Hungary", "Hungary"], "Project_ACR": ["FAWORIT 2016-2017"], "Technology_Description": "The main objective of our FAWORIT proposal is twofold: 1) to show the public how researchers with their innovative solutions affect our daily lives; 2) to encourage the youth \u2013 with a special focus on girls \u2013 to embark on scientific careers by involving young innovators in our programmes. Our main target group is students between the age of 8-20, but we aim to address all age groups with attractive programmes. Some novelties of our project: offering challenge-oriented activities \u2013 each of our 18 venues will present their innovative solutions related to interdisciplinary societal challenges; focussing on the concept of Responsible Research and Innovation - the audience will be informed about key elements of RRI, thus creating better understanding and fostering future involvement; launching \u201cScience in the City\u201d \u2013 a flash mob like activity, involving the public in spectacular experiments. We will apply an integrated approach in our project in which interdisciplinary challenges, innovative solutions, (young) researchers, their work and hobbies will be presented in an interactive, educating and entertaining way. The target audience can thus discover that being a researcher is cool and creative; researchers, but and young innovators are amongst us. Our objective is to have around 30000 visitors at the events, but a multiple of that number (around 500000) will see, hear or read about the Night. We intend to raise awareness of the European engagement in R&I; in the European Corners and at each venue related programmes of the European Union (FP7, H2020, especially MSCA) will be visible. The structure of the consortium: an innovative SME, a state-owned applied research institution, a highly innovative large company, a scientific association with a broad network of local member institutions all over Hungary and an independent think tank established by economists and sociologists together with numerous contributing partners of all kinds will ensure the success of the project.", "To": ["2017-11-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-NIGHT-2016 - European Researchers' Night"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Hungary"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Other"], "From": ["2016-04-01"], "Project_ID": ["722562"], "Call_for_Proposal": ["H2020-MSCA-NIGHT-2016"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI PAVIA", "UNIVERSITA DEGLI STUDI DI PAVIA"], "EU_Contribution": ["EUR 1 697 500"], "Project_Title": ["deTeRmine the trUe dEpth of DeEp subduction from PiezobaromeTry on Host \u2013inclusions Systems"], "Total_Cost": ["EUR 1 697 500"], "Country": ["Italy", "Italy"], "Project_ACR": ["TRUE DEPTHS"], "Technology_Description": "Subduction of one tectonic plate below another is the primary cause of catastrophic geological events such as earthquakes and explosive volcanism that directly impact thousands of kilometers of coastal and mountain areas located on convergent margins. Real-time geophysical or seismic data only provide static snapshots of these subduction zones today. Therefore, quantitative understanding of the rates and true depths of subduction can only be achieved by determining the pressure-temperature-time-depth histories of Ultra-High-Pressure Metamorphic (UHPM) rocks that have been subducted to pressures greater than 3 GPa and subsequently exhumed. Conventional mineral thermo-barometry is severely challenged in UHPM terraines and thus the mechanisms attending the downwards transport of crustal material, and its return back to the Earth\u2019s surface (exhumation), are still a matter of vigorous debate.", "To": ["2022-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-STG - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["714936"], "Call_for_Proposal": ["ERC-2016-STG"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 212 194,80"], "Project_Title": ["Travelling Sounds: A cultural analysis of sonic artefacts in postcolonial Europe"], "Total_Cost": ["EUR 212 194,80"], "Country": ["Denmark"], "Project_ACR": ["TRAVELLING SOUNDS"], "Technology_Description": "\"In this postcolonial and globalised world, the movement and criss-crossing of people, ideas, and sonic artefacts across the boundaries of nation states have become integral to the everyday cultural practices of individuals and groups. The vibrant connection between everyday cultural practices, artistic expressions, and new ways of thinking about culture in times of growing migratory movements and globalisation, has fascinated me ever since I started my PhD project on South Asian British musical cultures in the context of postcolonial history and theory. Aiming at establishing myself as an independent scholar, and at taking my expertise in cultural studies, sound studies and postcolonial studies to the next level, I am keen to study the postcolonial condition (Gilroy) of Europe not only through its musical, but also through its wider sonic cultures, taking into account sonic artefacts from different contexts, such as: sonic reinventions of urban space, the social functions of mobile devices, and the identificatory power of sound in cultural memory and commemoration. The overall aim of this project is to establish a comparative perspective which includes case studies from Denmark and the UK, and to investigate the cultural, social and political potential of sonic artefacts \u2013 music, voices, and everyday sounds \u2013 to forge a better understanding of Europe\u2019s transcultural and entangled postcolonial histories and how they have shaped contemporary sound cultures. To exemplify this, the project focuses on specific iconic events and artefacts such as the sonic-cultural politics of \u201cGreenlandic Square\u201d in Copenhagen, the postcolonial signature sound of the steel drum at Notting Hill Carnival in London, and the 2011 so-called \"\"Blackberry riots\"\" addressing its use of social media networks for messaging, activist organisation and sonic representation. The challenging question when looking at these diverse examples is how they are connected to Europe\u2019s postcolonial condition.\"", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["750199"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KATHOLIEKE UNIVERSITEIT LEUVEN"], "EU_Contribution": ["EUR 160 800"], "Project_Title": ["Synthesis of Spirooxindoles and INdoles pharmaceuticals using Metal-Organic Frameworks"], "Total_Cost": ["EUR 160 800"], "Country": ["Belgium"], "Project_ACR": ["SINMOF"], "Technology_Description": "SINMOF is a pioneering and structured effort to comprehensively address the introduction of different immobilised isolated catalytic active sites in solid hybrid materials to overcome the metal losses occurring with state-of-the-art homogeneous catalysts employed in the pharmaceutical industry. The convenient use of hybrid metal-organic framework materials (MOFs) respect to traditional state-of-the-art porous solid materials is due to (a) self-deactivation-resistant design of the active sites by (b) ultrastable catalytic site isolation. In the SINMOF project we will (1) design novel multifunctional MOFs as next generation catalysts for the synthesis of pharmaceutically active compounds in an economically and environmentally beneficial way; (2) apply MOF hybrid solids as heterogeneous catalysts to avoid the use of homogeneous metal catalysts in novel synthetic strategies of pharmaceuticals with the indole core and finally (3) derive structure-activity and selectivity relationships at the smallest possible length scales and with the highest possible sensitivities employing fluorescence microscopy. Using a two-stage research methodology, SINMOF will finally provide the most active and stable MOF catalyst for the synthesis of the indole-based neurotransmitter Sumatriptan and the anticancerigen spirooxindole SAR405838. The combined expertise of the fellow and host ensures the best chance for successfully completing the SINMOF objectives in a mutually beneficial manner. On one side, internal collaborations at the host institution will allow the access to state-of-the-art fluorescence microscopy methods, to get new insights into the molecular mechanisms underlying the novel catalytic systems. On the other side, a secondment at a world-leading research center in the homogeneous catalysis field will train the researcher in order to individuate the best molecular features for model homogeneous catalysts to be translated into selective heterogeneous MOF catalytic system.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["750391"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 200 194,80"], "Project_Title": ["Investigation of aberrant DNA methylation in malignant haematopoiesis"], "Total_Cost": ["EUR 200 194,80"], "Country": ["Denmark"], "Project_ACR": ["DNAmethAML"], "Technology_Description": "Acute myeloid leukaemia (AML) is an aggressive type of blood cancer characterized by uncontrollable growth of immature myeloid cells. Somatic mutations in diverse transcriptional regulators result in aberrant epigenetic landscape in leukemic cells, including patterns of DNA methylation. Due to its reversible nature, this epigenetic mark has been a promising therapeutic target and DNA methyltransferase inhibitors are already being used with varying degrees of success in clinic. The targeted improvement of existing therapies requires a better understanding of mechanisms how altered DNA methylation promotes malignancies. TET2, an enzyme catalysing DNA demethylation, is one of the most frequently mutated epigenetic regulators in AML. Its loss leads to hypermethylation at distal regulatory regions (or enhancers) and increased stem cell self-renewal and leukaemogenesis in the haematopoietic system. In the proposed work I plan to investigate the link between aberrant hypermethylation at enhancers and its role in developing and maintaining AML. Firstly, I will take advantage of clinically relevant AML mouse models that combine TET2 deficiency with AML-specific alterations and annotate DNA methylation-sensitive enhancers using high-throughput sequencing methods (MethylC-seq, ATAC-seq and ChIP-seq). Secondly, I will perform a positive-selection CRISPR-based high-throughput enhancer screen to identify DNA methylation-sensitive enhancers that inhibit leukemic stem cell self-renewal (i.e. tumour suppressive regulatory regions). Finally, I will identify and study the function of transcription factors which binding is lost due to aberrant DNA hypermethylation at these sites. The proposed work will be both discovery-based (genome-wide level) as well as mechanistic.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["749362"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KOBENHAVNS UNIVERSITET"], "EU_Contribution": ["EUR 212 194,80"], "Project_Title": ["Riding to extinction: epigenomics of the Ice Age horses"], "Total_Cost": ["EUR 212 194,80"], "Country": ["Denmark"], "Project_ACR": ["EPIRIDE"], "Technology_Description": "The EPIRIDE project will use a combination of novel experimental and computational techniques to explore the role of epigenetics in long-term adaptive strategies of large vertebrates in response to rapid climate change. Modern and ancient horse bone samples will be analysed for epigenetic markers using advanced high-throughput sequencing approaches, and the epigenomic landscapes will be contrasted over a 30,000-year record of major climatic and environmental shifts. EPIRIDE has strong potential to reveal key genomic regions for climate adaptation in large herbivores, with considerable implications for conservation genetics and livestock management.", "To": ["2019-12-31, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["748766"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE CATHOLIQUE DE LOUVAIN"], "EU_Contribution": ["EUR 160 800"], "Project_Title": ["Multi-layered biomimetics of lytic polysaccharide monooxygenases"], "Total_Cost": ["EUR 160 800"], "Country": ["Belgium"], "Project_ACR": ["MOMIMIC"], "Technology_Description": "The high stability of components like cellulose limit the efficiency and cost effectiveness of biofuel or chemical production from lignocellulosic biomass. Thus, the ability of the recently discovered class of metalloenzymes, lytic polysaccharide monooxygenases (LPMO), to enhance the efficiency of recalcitrant polysaccharide degradation makes understanding these enzymes invaluable for carbon friendly sustainable chemical and energy development as prioritized under the Horizon2020 program. ", "To": ["2020-01-07, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-08"], "Project_ID": ["753953"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KATHOLIEKE UNIVERSITEIT LEUVEN"], "EU_Contribution": ["EUR 172 800"], "Project_Title": ["Designing Novel Efficient Catalytic Strategies for the Transformation of Lignocellulose into Lignin-derived Chemicals and Valorisable Carbohydrates"], "Total_Cost": ["EUR 172 800"], "Country": ["Belgium"], "Project_ACR": ["CATLIGCAR"], "Technology_Description": "The utilization of renewable lignocellulose biomass (composed of cellulose, hemicellulose and lignin) alternative to fossil fuels is crucial for long-term economic and social stability. In this context, the catalytic reductive lignocellulose fractionation (CRLF) process has received tremendous research interest as this strategy enables one-pot conversion of lignocellulose into useful lignin-derived chemicals, while retaining a solid (hemi)cellulose fraction that can be used for the production of fuels, chemicals or paper. The development of promising heterogeneous catalysts having abundant redox and acid properties, along with the application of a proper solvent is a great challenge for efficient CRLF process. ", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["747968"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF SOUTHAMPTON"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Art and Ethics: Restarting and Advancing a Stalled Debate"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["Art and Ethics"], "Technology_Description": "This project is a work of philosophy that investigates how intrinsic ethical properties are realized in artworks and other aesthetic and creative objects and practices, and in what respects their aesthetic values are determined by these properties. The project innovates in three principal ways. First, it identifies and articulates novel ways by which artworks and similar objects and practices come to exhibit ethical properties, where the existing literature in this area relies exclusively on just one way this can occur. Second, it diagnoses why the literature on the question of ethico-aesthetic value interaction has stagnated for almost a decade, by revealing the vague and inconsistent conceptual tools on which its theorists have relied until now, and which have inhibited its progress. Finally, it uses the preceding two innovations to articulate a new and satisfactory theory about how ethical properties determine aesthetic values.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["750848"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE UNIVERSITY OF EDINBURGH"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Integrated drug discovery approach to generate brain-penetrant inhibitors of glioblastoma cell proliferation"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["BRAINHIB"], "Technology_Description": "Glioblastoma multiforme (GBM) is the most common and aggressive cancer that begins within the brain. Without treatment the average survival following diagnosis is merely 3 months. Although clinically-approved kinase inhibitors present promising features to treat GBM, most of them do not cross the blood brain barrier (BBB), impeding their clinical use in GBM patients. We propose an agile approach that combines ligand-based drug design of highly-focused compound libraries and first-in-class phenotypic assay for simultaneous screening of BBB penetration, unspecific toxicity and anticancer properties, in an iterative manner. This approach will allow a one-step selection of hit / lead compounds from in-house generated compound libraries that cross the BBB to accelerate the design of CNS-active anticancer drugs. Furthermore, the use of chemical proteomics and the state-of-the-art proteomics techniques will facilitate the identification of the kinases and / or pathways that are involved in the observed phenotype, which could result in the discovery of novel GBM oncotargets and unknown modes of action. This highly innovative integrated approach has the potential to speed up preclinical drug discovery efforts in CNS diseases, and in doing so, promote European Scientific Excellence. As a developer and provider of such tools, the applicant will be positioned in a privileged position for starting cross-disciplinary collaborations with academics and Pharma across Europe and for establishing herself as an independent researcher.", "To": ["2020-02-29, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-03-01"], "Project_ID": ["749299"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Plotting the material flows of commonplace Late Bronze Age Seals in Western Eurasia"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["PLOMAT"], "Technology_Description": "The aim of PLOMAT, an innovative project on Commonplace Seals of Late Bronze Age Western Eurasia, is to offer new perspectives on the study of non-\u00e9lite populations and the small-scale networks that operated at a time of art internationalization in the ancient world. PLOMAT will map the flows of materials and ideas in the Late Bronze Age by studying cylinder seals, which were an important and widely used class of object. Combining Digital Humanities and scientific material analysis with innovative archaeological and art historical theories, it will study for the first time the production and consumption of \u2018commonplace\u2019 cylinder seals in mid-second millennium BCE, which spread over a wide area from the Eastern Mediterranean to Central Western Asia. Seemingly produced en-masse on \u2018low-cost\u2019 materials, these artefacts represent an ideal subject for studying the flow of ideas across large areas in the ancient world. By developing and implementing novel computational methods and material analysis, and engaging with a bottom-up social archaeological approach, it will chart movements of people and ideas throughout East and West, provide for the first time a clear large volume of material analysis characterization, explore the appropriation and/or rejection of Mesopotamian material and visual culture and unveil elements of non-\u00e9lite history of the region and its peoples. In addition to numerous essential transferable skills invaluable to the future world-class researcher and academic, PLOMAT will provide training in GIS and spatial analysis, exploratory multivariate statistics and X-ray fluorescence analysis of materials using Bruker Portable XRF Spectrometers. The expertise of senior researchers at the University of Cambridge, combined with available resources and facilities make it the ideal organisation to host the project and ER.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["748293"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Water management strategies and climate change in the Indus Civilisation"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["WaMStrIn"], "Technology_Description": "WaMStrIn will re-evaluate the relationship between human settlement and the changing hydrological network of the Indus area of Pakistan during the emergence of first urban centres in ancient South Asia (2500-1900 BC). The ancient Indus was the most extensive of the three so-called cradles of Old World civilisation and a number of attempts have been made to trace the network of palaeorivers that watered this region and sustained its ancient population. Using a novel combination of multi-temporal satellite remote sensing, GIS-based topographic analysis, geostatistics and network analysis WaMStrIn will overcome previous problems in the detection of ancient rivers and associated archaeological sites. In doing so WaMStrIn will provide new hypotheses and quantifiable open access data on (1) past water management, (2) the mechanism employed to cope with changing water availability and (3) the consequences of a long-term shift towards more arid conditions for South Asia's earliest large-scale, urban, and interconnected society.", "To": ["2020-01-01, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-02"], "Project_ID": ["746446"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CONSIGLIO NAZIONALE DELLE RICERCHE"], "EU_Contribution": ["EUR 180 277,20"], "Project_Title": ["White Light Emitting Lanthanide Metal Complexes for Electroluminescent Materials"], "Total_Cost": ["EUR 180 277,20"], "Country": ["Italy"], "Project_ACR": ["WHITELIGHT"], "Technology_Description": "There is an urgent need to develop a new generation of more efficient and durable illumination sources to surpass the limitations of the conventional lighting systems. Solid State Lighting sources based on Light Emitting Diodes (LEDs) or Organic LEDs (OLEDs) devices are emerging as the next generation systems for general illumination. White LEDs on the market outperform the traditional incandescent and fluorescent lamps, both in term of efficiency and lifetime. More work has still to be done to develop their organic counterpart, OLEDs. These offer the distinctive possibility to fabricate large area flat and also flexible devices by vacuum or solution processing, i.e. by potentially less expensive and less energy-consuming production protocols. For this, the development of electroluminescent materials that show high brightness, easy synthesis, good chemical and electrical stability, low cost, and simple processing is actively pursued. In this context, WHITELIGHT targets the development of single-molecule white light emitting materials for the fabrication of OLEDs, containing Eu(III) (red), Tb(III) (green) lanthanide ions and bis(2-pyridyl)amine based ligands (blue) emitters. This is a very ambitious and multidisciplinary goal that requires a range of expertise spanning from theoretical chemistry to physical device fabrication and testing. The research unit at the hosting institution has a strong background in the photophysics of materials for light/ energy conversion, complemented by an expertise in the design and synthesis of organic luminescent materials, as well as the fabrication and testing of electroluminescent devices. On the other hand, the Experienced Researcher has a strong background in the synthesis of luminescent lanthanide complexes. This unique combination of expertise is a major factor for the successful implementation of the proposed research.", "To": ["2020-01-01, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations"], "From": ["2018-01-02"], "Project_ID": ["749287"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["LUNDS UNIVERSITET"], "EU_Contribution": ["EUR 185 857,20"], "Project_Title": ["Assessment of African Vegetation Resources: New Perspectives from Satellite Passive Microwave Datasets"], "Total_Cost": ["EUR 185 857,20"], "Country": ["Sweden"], "Project_ACR": ["AfriVeg"], "Technology_Description": "Livelihoods of most of the African population strongly depend on local ecosystem services, such as grazing, agriculture, firewood, and construction timber. Although an overall greening trend is shown by both dynamic global vegetation models (DGVMs) and Earth Observation (EO), large uncertainties for each data source are reported and significant divergence between outputs have been documented, impeding accurate assessment of vegetation dynamics in Africa. The overall purpose of this project is to develop methods to for an improved assessment of African vegetation resources based on new capabilities originating from satellite passive microwave observations. Specifically, the vegetation optical depth (VOD) derived from passive microwave data is sensitive to the water content in both the green and woody (i.e., branches and stems) vegetation components which is different from the traditional optical-infrared greenness driven vegetation index (VI) being primarily sensitive to chlorophyll abundance. By combining multi-frequency VOD retrievals with long-term VI datasets, in situ measurements, and DGVMs, this project will accurately quantify woody biomass, green biomass, net primary production (NPP), vegetation phenology and ecosystem functional types (EFT) in Africa, as well as their long-term changes and the climate and socio-economic drivers. The results are expected to pave the road for improved vegetation resource management in Africa and understanding of global carbon cycling. To achieve this, I will be trained in cutting edge skills (EO time series, flux measurements and ecosystem modeling). My major mobility activity will be sparking the integration of passive microwave VOD, carbon and water flux measurements and DGVMs for an improved understanding of changes in vegetation resources and drivers hereof in Africa.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["746347"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE LIBRE DE BRUXELLES"], "EU_Contribution": ["EUR 240 530,40"], "Project_Title": ["Tools to Carve out Conformal Field Theories"], "Total_Cost": ["EUR 240 530,40"], "Country": ["Belgium"], "Project_ACR": ["TcCFT"], "Technology_Description": "Recently a number of research efforts have been dedicated to the conformal bootstrap. The basic principle is that conformal symmetry and quantum mechanics should suffice to fix uniquely the dynamics of Conformal Field Theories (CFTs), which lie at the fixed points of the renormalisation group flow. This has led to ground-breaking results, such as the unprecedented determination of scaling dimensions in non-trivial CFTs including the celebrated Ising model in 3d. Thus far these endeavours have focused only on the simplest examples of correlation functions with low-spin operators or to supersymmetric CFTs.", "To": ["2020-09-24, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-25"], "Project_ID": ["747228"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FUNDACAO CALOUSTE GULBENKIAN"], "EU_Contribution": ["EUR 148 635,60"], "Project_Title": ["Dissection of the mechanisms causing the epistasis between antibiotic resistance mutations in Escherichia coli"], "Total_Cost": ["EUR 148 635,60"], "Country": ["Portugal"], "Project_ACR": ["ResistEpist"], "Technology_Description": "Antibiotic resistance is a major threat to public health. Bacteria can become resistant by acquiring genes that counteract the action of antibiotics or by mutation of their targets. These targets are usually involved in essential processes and typically resistance mutations can impair bacterial growth in absence of antibiotics. However, combination of certain mutated alleles can result in an alleviation of this cost, thus favouring the acquisition of multiple resistances. This project aims to understand the mechanisms underlying the epistasis between resistance mutations. Decreased biosynthesis has been considered the main cause of the fitness cost associated to antibiotic resistance mutations. However, our preliminary results suggest the existence of additional causes, such as genomic instability or proteostasis imbalance. The study of these phenotypes in single and double resistant mutants of Escherichia coli will allow us to determine the nature of these epistatic interactions, as well as further understanding essential biological processes, and will provide information for the development of new treatments against multi-resistant infections.", "To": ["2020-11-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Portugal"], "Activity": ["Research Organisations"], "From": ["2018-12-01"], "Project_ID": ["746690"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["SYDDANSK UNIVERSITET"], "EU_Contribution": ["EUR 200 194,80"], "Project_Title": ["COULD SENESCENCE BE ADAPTIVE? CAUSES AND CONSEQUENCES OF AGING ACROSS THE TREE OF LIFE"], "Total_Cost": ["EUR 200 194,80"], "Country": ["Denmark"], "Project_ACR": ["WHYAGE"], "Technology_Description": "Why do organisms age? This is surely one of the most compelling questions in biology. With advancing age, organisms can see physiological decline leading to higher mortality and lower fertility, a process known as \u2018senescence\u2019. The foundations of aging research state senescence should be inevitable in any organism, and is likely a by-product of attenuation in force of selection with age. But is senescence inevitable? Could senescence be adaptive?", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Denmark"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["746235"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Ironworking technology and social complexity of rural comunities during the Early Medieval Ages"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["Basquesmith"], "Technology_Description": "The application of scientific techniques to analyse archaeological materials has greatly influenced modern archaeology, providing archaeologists with the tools to generate datasets, such as those associated with chronological dating and chemical compositions, from which more rigorous interpretations can be developed. The Basquesmith project aims to investigate ironworking production during Early Medieval (EM) times by applying microscopic techniques on an assemblage of materials excavated in rural settlements in the Basque Country (northern Spain), a region renowned for the superior quality of its iron products. Characterisation of the manufacture and repair methods used, the quality of the utensils produced, and the debris generated, will provide valuable insight into which production occurred at the sites. The originality lies in the artefacts themselves as well as the archaeometallurgical approach to investigate these assemblages. Common utensils such as ladles or keys made from iron, which are exceptionally rare in EM rural contexts, allow ironworking to be explored on rural implements from rural communities rather than prestige items from urban contexts. This will result in a truly utilitarian project combining history, archaeology and materials science to investigate a much neglected area for EM Spain. Basquesmith is highly committed to EU's strategy endorsed in the field of Cultural Heritage and is in an excellent position to carry out this research through the promotion of such an interdisciplinary approach. Moreover, Basquesmith integrates the applicant\u2019s knowledge in material science with a top level research group (GIPyPAC) at the University of Basque Country. This network will not only encourage dissemination of the research within the academic literature and spotlight the cultural heritage of the Basque region, but it will also provide a framework which can be applied to the evaluation of technology in rural communities at other archaeological sites.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["746058"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN"], "EU_Contribution": ["EUR 175 866"], "Project_Title": ["Firescape genomics: predicting plant responses to changing fire regimes"], "Total_Cost": ["EUR 175 866"], "Country": ["Ireland"], "Project_ACR": ["FIRESCAPE"], "Technology_Description": "Increases in the frequency of wildfire driven by invasive plant species, land use change and climate change are occurring globally. The current mismatch between past and present fire regimes means we have little ability to predict how, or if, ecosystems will adapt to these novel pressures. However, many European plant species have been introduced into Australia where fire frequency exceeds levels found in the species native range. My project, hosted by Trinity College Dublin and supervised by Professor Yvonne Buckley, will capitalise on this unique opportunity to predict how species will respond to increases in fire frequency that are occurring in Europe under climate change. I have already produced an existing genomic database from hundreds of individuals across fire frequency gradients in Australia. The task now is to strategically sample areas of Europe to establish the native baseline and use cutting-edge spatial analyses to investigate the phenotypic and genomic basis underlying adaptation to changing fire regimes in European plant species. My Training Plan includes specific professional development programs to enhance my critical skills in leadership, grant writing, teaching and global networking. During the fellowship, I will improve essential competencies needed to compete at ERC-level including mastering sophisticated analytical and bioinformatics tools. My interdisciplinary research, drawing together population ecology, invasive species management and landscape genomics will make a critical contribution to the European Climate Action priority to anticipate and minimise damage caused by climate change. Following my strong track record in science communication, I will disseminate my work widely to the scientific community, end-users and to the general public at the broadest level. The prestigious Marie Sk\u0142odowska-Curie fellowship will allow me to develop the professional maturity to establish myself among the leaders of the European research community.", "To": ["2019-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Ireland"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["746191"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITEIT GENT"], "EU_Contribution": ["EUR 258 530,40"], "Project_Title": ["Multitasking Nanoparticles for Intracellular Bioimaging and Biosensing"], "Total_Cost": ["EUR 258 530,40"], "Country": ["Belgium"], "Project_ACR": ["NanoIntra"], "Technology_Description": "The development of specifically designed nanomaterials for advanced medical applications such as theranostics has become a major technical challenge with great potential societal and economic outcomes. Nanomedicine and related techniques hold great promises for improved diagnostic and treatment of widely spread diseases such as cancer. This project, entitled NanoIntra, aims at developing novel multitasking nanoparticles as advanced tools for highly localized and ultrasensitive intracellular imaging and biosensing. These nanoprobes should provide new insights in the spatial and temporal processes at play in live cells and therefore reveal part of their mystery. Such functional objects are achieved through the design of a complex architecture which involves quantum dots as bright and stable luminescent markers encapsulated in a protective silica matrix. These nanoparticles are combined with plasmonic nanocrystals, which offer new strategies for their photothermally induced intracellular delivery. The targeting and imaging of specific subcellular structures is then achieved thanks to proper surface functionalization of the nanoparticles. In addition, the plasmonic nanocrystals also allow these nanoparticles to be used as Surface Enhanced Raman Scattering (SERS) biosensors. Finally, for a higher control on the use of such nano-biosensors, optical tweezers are used to purposefully manipulate and position the nanoparticles inside the cells at the region of interest. Besides their application in cell labeling and biosensing, these functional nanoparticles have tremendous potential applications in the fields of theranostics, nanomedicine and nanobiophotonics, and NanoIntra constitutes a first step toward the development of a full lab-on-a-particle. Thus, through the synthesis and characterization of novel materials and their application to biotechnology, NanoIntra is a multidisciplinary research and training project at the interface between physics, chemistry and biology.", "To": ["2020-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-GF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-GF)"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["702300"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITE DE RENNES I"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["MEMBRANE PROTEINS OF ELECTROACTIVE BACTERIA PROBED AT LIPID LAYERS ONTO MODIFIED ELECTRODES"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["MELBA"], "Technology_Description": "MELBA aims at developing an efficient and versatile electrochemical platform for probing the charge transfer properties, electronic or protonic, of membrane proteins extracted from Gram negative electroactive bacteria. This 2 years research project will be conducted at the Universit\u00e9 de Rennes 1, UR1 France, including a six months Secondment at Universidade Nova de Lisboa, UNL Portugal. Carbon electrodes will be covalently modified with pH-responsive electrophores through surface modification techniques, WP1 Task1. Lipid layers will be deposited onto the modified electrodes to create an artificial membrane as a host for extracted membrane proteins, WP1 Task2. The experienced researcher Dr. Leb\u00e8gue will learn protein expression, extraction, purification and characterization during the six months Secondment at UNL, WP2 Task3. Finally extracted proteins will be incorporated into the artificial membrane deposited onto the modified electrodes and their electronic and/or protonic charge transfer properties will be characterized, WP2 Task4.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["745689"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF DURHAM"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Isotopic evidence for diet and mobility during the Neolithic transition to farming in the Near East"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ISONEO"], "Technology_Description": "The Neolithic transition represents perhaps the most significant development in human history. In Europe the \u2018Neolithic package\u2019 arrived as a whole, and has been studied in detail using isotopic and genetic methods, but few isotopic studies have addressed the earlier and more complex transition in the Near East. Thus currently we know little about the changes in diet and mobility of individuals and cannot compare this crucial region to the later transition in Europe or to parallel transitions elsewhere. ISONEO will investigate the composition of diet in selected Neolithic populations of the Near East using carbon and nitrogen isotope analysis. Using strontium and oxygen isotopes in human tooth enamel ISONEO will explore the importance of migration in creating and sustaining the population of Pre-Pottery Neolithic B megasites and in the lifeways of the desert populations of the Pottery Neolithic and Chalcolithic in Jordan, Israel, and NW Saudi Arabia. The main sites used will be \u2019Ain Ghazal, Basta, Ba\u2019ja, Kharaysin, Mallaha, Beisamoun, and Shubayqa. The results will be used to build a regional model of the diet, mobility and social changes that took place during the Neolithic transition in the Near East in a holistic synthesis with previous research based on traditional archaeological evidence including archaeobotany and archaeozoology. The Experienced Researcher, Dr Jonathan Santana will be supervised and trained by Dr Andrew Millard. Within the research intensive context of the Department of Archaeology at Durham he will enhance and expand his existing research skills, knowledge of practical techniques, and theoretical knowledge. He will be trained in stable isotope analysis and the interpretation of isotopic data, which will enable him to undertake the research for ISONEO. These new competencies will enhance his skills in scientific methods and critical thinking applied to archaeology and will increase his prospects for obtaining a permanent academic position.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["750460"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Seasonal Prediction of Fire danger using Statistical and Dynamical models"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["SPFireSD"], "Technology_Description": "Wildfires have a great impact on the environment and can pose a threat to property and human lives and health. The occurrence of fire in natural vegetation is dependent on human activities and climate variability. In tropical areas such as the Amazon basin and Indonesia, wildfires are greatly affected by inter-annual fluctuations in tropical Sea Surface Temperatures (SSTs). During the El Ni\u00f1o events of 1997-1998 and 2015-2016, uncontrolled wildfires caused record impacts on health, transportation and the economy. The European countries of the Mediterranean basin are frequently plagued by drought episodes (e.g. during the summer of 2016), causing dangerous wildfires which result in deaths, health problems and economic losses.", "To": ["2019-09-05, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-09-06"], "Project_ID": ["748750"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Covalent-ligation-assisted elucidation of protein-aromatic foldamer interactions"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["PROFOLIG"], "Technology_Description": "The development of ligands that selectively bind to a given protein surface is a challenging area of research with potential applications in diagnostics, pharmacology or therapy. Current approaches include small molecule screening, the design of medium sized epitope mimetics (e.g. alpha helix mimetics) and directed evolution methodologies (e.g. ribosome display).", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2017-03-01"], "Project_ID": ["751019"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FUNDACIO PRIVADA INSTITUT CATALA D'INVESTIGACIO QUIMICA"], "EU_Contribution": ["EUR 170 121,60"], "Project_Title": ["Photocatalysis induced by copper complexes supported on Silica materials-Study in Flow processes"], "Total_Cost": ["EUR 170 121,60"], "Country": ["Spain"], "Project_ACR": ["PhoCuS-Flow"], "Technology_Description": "PhoCuS-Flow project aims to contribute to the European Research Area (ERA) by developing a new generation of sunlight activated copper photocatalysts supported on mesoporous silica. Three novel concepts are proposed: i) use of tris(triazolyl)methanol-Cu-complexes (developed in the host group) as photocatalysts in organic reactions, ii) the immobilization of the complexes on mesoporous silica materials to be used as heterogeneous and recyclable catalysts and iii) implementation of a continuous flow setup in order to gain in efficiency and potential industrial applicability. These objectives have a direct impact in some of the \u2018Societal Challenges\u2019 listed in H2020 i.e. \u2018Secure, Clean and Efficient Energy\u2019 and \u2018Climate action, Environment, Resource Efficiency and Raw Materials\u2019.", "To": ["2020-04-30, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2018-05-01"], "Project_ID": ["746190"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["OSASEN SENSORES S.L."], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["A Low-cost disposAble eleCTrochemical biOsensor for Point Of Care (POC) hypolactasia diagnostic testing"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["LACTOPOC"], "Technology_Description": "LACTOPOC is a multidisciplinary research and training programme targeted to provide Dr. Macia-Gonzalez, an expert in electrochemical analytical platforms design, with new entrepreneurial and scientific skills on translation of innovative biosensor technology into Point of Care (POC) diagnostic devices.", "To": ["2019-05-01, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-SE - Society and Enterprise panel"], "Coordinated_in": ["Spain"], "Activity": ["Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2017-05-02"], "Project_ID": ["749368"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["HERIOT-WATT UNIVERSITY"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Highly Disruptive and Compact Antenna Systems for Small Satellites with Application to Surveillance, Environmental and Crop-Growth Analysis, Enabling European Union Dominance in the Space Industry"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["CSA-EU"], "Technology_Description": "Compact satellites are transforming space-based surveillance systems. Typical configurations include a network of small satellites that can offer increased coverage and enhanced data collection rates when compared to conventional large scale systems. Microsatellites can also drastically reduce launching costs and mission development time, thus making remote sensing technologies more cost effective. Applications include vehicle tracking, weather monitoring, maritime surveillance, crop growth analysis, and climate change observation. However, with satellite miniaturization, new design aspects arise. All satellite components have to be cleverly packaged within a small payload and materials must accommodate the harsh operating environments of space. ", "To": ["2018-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-01-01"], "Project_ID": ["709372"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITY OF BRISTOL"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Developing the Next Generation Framework for Testing Nonlinear Dynamic Structures."], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["TNS"], "Technology_Description": "When designing new structures and devices, engineers are completely dependent on mathematical models to ensure that their designs function as intended. As technological boundaries are pushed to the limits, systems become nonlinear \u2013 the response of the system is no longer proportional to the input. These nonlinear systems can exhibit a wide range of complicated behaviour that is very difficult to predict and potentially disastrous. Take for example the F-117A Night Hawk stealth jet. Despite extensive modelling and design work, at an airshow in 1997 in Maryland, Essex, USA, it encountered a disastrous instability known as flutter. The aircraft was lost. ", "To": ["2018-04-30, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["703204"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["VIB"], "EU_Contribution": ["EUR 160 800"], "Project_Title": ["IgA-based oral therapy for protection of piglets against infection with enterotoxigenic E. coli."], "Total_Cost": ["EUR 160 800"], "Country": ["Belgium"], "Project_ACR": ["ImmunoFarm"], "Technology_Description": "Postweaning diarrhoea (PWD) in pigs is responsible for important economic losses in the global pig rearing industry. This illness is predominantly caused by enterotoxigenic E. coli strains carrying the F4 (ETEC-F4) and F18 (ETEC-F18) fimbriae. There is no treatment available to fight PWD except using antibiotics. However, the prophylactic use of antibiotics is forbidden in Europe and is expected to become forbidden in the rest of the world because of increasing abundance of resistance genes. Delivery of sIgA to mucosal surfaces as passive immunotherapy agent is a very promising strategy to prolong maternal lactogenic immunity against post-weaning infections. The aim of this project is to produce sIgA-like anti-ETEC antibodies in a cost-effective platform. Twenty different anti ETEC-F18 antibodies in a sIgA-like format will be engineered from phage display-selected variable domains (VHHs) currently available in the host institute. The synergistic or additive neutralisation effect of oligoclonal antibody cocktails will be evaluated using ETEC-F18 in vitro villus adhesion assays. The different antibodies will be produced first by transient expression in Nicotiana benthamiana and second in seeds of Arabidopsis thaliana transformants. An in vivo ETEC-F18 challenge will then be performed using two groups of piglets, one receiving the most effective seed-derived feed formulations and the other one receiving regular feed (negative control group). The sIgA antibodies of the elite oligoclonal formulation will then be transferred to biosafe soya seeds as production platform. These steps will lead towards the development of scalable procedures to obtain a cost effective bulk production of a feed based prophylaxis against ETEC.", "To": ["2017-04-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Belgium"], "Activity": ["Research Organisations"], "From": ["2015-05-01"], "Project_ID": ["658701"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["CENTRE EUROPEEN DE RECHERCHE EN BIOLOGIE ET MEDECINE"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["\u201cQuantitative analysis of the molecular and cellular behaviors associated with cardiac valve morphogenesis in pathological and regenerative contexts\u201d"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["ZEBRA-VALVE"], "Technology_Description": "Cardiovascular diseases (CVDs) take a huge toll on the world population. An estimated 19 million people died from CVDs in 2010, representing 30% of all global deaths. Abnormal blood circulation is widely recognized as a cardiovascular risk factor and mechanotransduction has been shown to trigger pathologies such as atherosclerosis1, cardiomyopathies2 and valvulopathies3. Mechanotransduction is the conversion of a mechanical stimulus into a biological response. It is central to the coordination between mechanical forces generated by flowing blood and heart valve morphogenesis. In the developing heart, the heartbeat and the blood flow signal to endocardial cell (EdC) progenitors through mechanosensitive proteins which in turn modulate the genetic program controlling cardiogenesis4. It is essential to determine how mechanical forces control pathway activation and morphogenesis in vivo because the mechanical stimuli experienced by EdCs are too complex to be faithfully reproduced in vitro. This timely proposal aims to uncover the cellular molecular programs activated in EdCs in response to mechanical forces during normal heart valve development and address their potential function in valve regeneration. My hypothesis is that endocardial mechanotransduction and mechanical forces are not only key for the morphogenesis of the valve, but also for their maintenance and repair. Specifically I aim to investigate the spatial and temporal nature of endocardial cellular behaviors necessary for cardiac valve morphogenesis in normal, pathological and regenerative contexts.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2017-04-01"], "Project_ID": ["708312"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["QUEEN MARY UNIVERSITY OF LONDON", "QUEEN MARY UNIVERSITY OF LONDON", "TEL AVIV UNIVERSITY"], "EU_Contribution": ["EUR 991 750"], "Project_Title": ["Spectral theory of random operators"], "Total_Cost": ["EUR 991 750"], "Country": ["United Kingdom", "United Kingdom", "Israel"], "Project_ACR": ["SPECTRUM"], "Technology_Description": "The theme of this proposal is the study of random operators associated with some geometric structure, and the influence of the geometry on the spectral properties of the operator. Such operators appear in problems from theoretical physics, and lead to new and interesting mathematical structures.", "To": ["2020-05-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2014 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2015-06-01"], "Project_ID": ["639305"], "Call_for_Proposal": ["ERC-2014-STG"]}, -{"Partners": ["ASSOCIATION GENETHON"], "EU_Contribution": ["EUR 185 076"], "Project_Title": ["Correction of duplications in the DMD gene by a CRISPR/Cas9 approach"], "Total_Cost": ["EUR 185 076"], "Country": ["France"], "Project_ACR": ["DMD2CURE"], "Technology_Description": "Duchenne muscular dystrophy is an X-linked recessive muscle-wasting disease, characterized by progressive weakening of skeletal, respiratory, and cardiac muscle followed by necrosis and fibrosis. DMD affects ~1:3,500 live male births and is associated with delayed motor milestones. DMD occurs as a result of mutations within the DMD gene that lead to premature termination of translation. The most frequent type of mutations are exonic deletions and duplications that induce a frame-shift in the protein-coding sequence. To date no effective treatment exist for this disorder.", "To": ["2019-02-28, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Research Organisations"], "From": ["2017-03-01"], "Project_ID": ["703093"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["TECHNISCHE UNIVERSITAET WIEN"], "EU_Contribution": ["EUR 178 156,80"], "Project_Title": ["Slow-Fast Systems in Cellular Biology"], "Total_Cost": ["EUR 178 156,80"], "Country": ["Austria"], "Project_ACR": ["SFSysCellBio"], "Technology_Description": "Mathematical modelling has emerged as an important tool to handle the structural complexity of cellular processes and to gain better understanding of their functioning and dynamics. We propose to develop methods for the mathematical analysis of ODE models arising in cell biology. We focus on models of great biomedical importance, i.e. cell division cycle, NF-kB signalling pathway, and the p53 system. Pertinent mathematical questions of biological interest are: existence and stability of equilibria, periodic oscillations, switching phenomena, and bifurcations.", "To": ["2018-08-29, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Austria"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-08-30"], "Project_ID": ["661650"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["FUNDACIO PRIVADA INSTITUT CATALA DE PALEOECOLOGIA HUMANA I EVOLUCIO SOCIAL"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Integrative Approaches to Dental Wear: Non-Masticatory Tooth-Use Across the Mesolithic-Neolithic Transition Among Iberian Foraging and Farming Societies"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["IDENTITIES"], "Technology_Description": "The IDENTITIES project investigates human dental wear related to the non-masticatory use of the dentition (the habitual use of \u201cteeth-as-tools\u201d) among human groups that span the Mesolithic-Neolithic Transition in the Iberian Peninsula \u2013 a period of complex social, economic, and technological reorganization corresponding to a shift from hunting and gathering to a dependence on domesticated plants and animals. A lifetime of using the teeth for habitual, manipulative tasks leaves distinct traces on enamel, and these idiosyncratic patterns of wear provide biocultural markers of social identities when aligned with information on sex, age, occupation, or status of individuals across archaeological samples. Human dental remains from archaeological sites across the Iberia provide an ideal regional focus for exploring biocultural changes related to tooth-use during a crucial prehistoric socioeconomic transition. IDENTITIES is interdisciplinary, bringing together experts in microscopy, experimental methods, bio/archaeology, and paleoanthropology through an integrative methodology to document non-masticatory dental wear. The methodologies include recent advances in Gigapixel-like imaging strategies, confocal and scanning electron microscopy, and three-dimensional dental topographic methods to analyze experimentally-worn and archaeological samples. The integrative methodology was also established to cross-validate each method (presently an unresolved issue), and advance the study of material surface modification of biological and archaeological materials generally. In addition to providing an intellectual impact through methodological advances, the same data will directly address how biocultural changes in non-masticatory tooth-use reflect changing social identities across archaeological groups of the last foraging peoples (Mesolithic), nascent farming societies (Neolithic), and established agriculturalists (Chalcolithic) in the Iberian Peninsula.", "To": ["2019-09-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-10-01"], "Project_ID": ["749188"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["CHALMERS TEKNISKA HOEGSKOLA AB"], "EU_Contribution": ["EUR 185 857,20"], "Project_Title": ["Innovative FRET-based toolkit for screening of drugs to fight miRNA-related diseases and its use in the development of cancer treatment with miRNA-96 as a therapeutic target"], "Total_Cost": ["EUR 185 857,20"], "Country": ["Sweden"], "Project_ACR": ["DrugSearchTool"], "Technology_Description": "The overall goal of this project is to develop a universal FRET-based toolkit for screening of drugs targeting microRNA (miRNA). Specific outcome will be a high-throughput assay for finding drugs targeting miRNA-96, a tumor-suppressing miRNA in pancreatic cancer cells. FRET is the technique of choice and recently, Prof. Marcus Wilhelmsson, Chalmers University of Technology (CHALMERS; project main supervisor) pioneered the development and photophysical characterization of fluorescent base analogues (FBAs) optimized for high-resolution FRET analysis of nucleic acid systems. There is an urgent need in pharmaceutical industry for an in vitro, cell-free, pre-miRNA-small molecule interaction high-throughput assay and also to increase the understanding of the nature of miRNAs. In this project, the unique FRET FBAs will be utilized to develop such assays and to provide new knowledge regarding miRNA structure, dynamics and interactions with other biological molecules or drugs. Apart from taking on the new research field stated above and developing my professional skills, I will bring in new competences to CHALMERS in RNA biochemistry (from the University of Warsaw and Max Planck Institute in G\u00f6ttingen). Moreover, as part of my training, I will carry out research at AstraZeneca (AZ) and Gothenburg University (UGOT) through secondments. CHALMERS/AZ/UGOT have an established collaboration and I will take full advantage of their R&T capacities in order to gain interdisciplinary and intersectoral expertise as well as to master my skills in scientific communication, scientific writing, coordinating research projects, results exploitation, critical assessment, mentoring, supervision, presentation and networking with other researchers across the globe. This MSCA Postdoctoral Fellowship will help me reaching a position of professional maturity invaluable for starting up my own research group or taking leading roles in industrial R&D organizations.", "To": ["2020-08-31, Grant Agreement signed"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-09-01"], "Project_ID": ["753595"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF DURHAM"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Testing the role of thermo-chemical piles in the generation and continuation of plate tectonics"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["TEROPPLATE"], "Technology_Description": "The mechanics of plate tectonics (the movement of the Earth's surface) is a fundamental scientific question in understanding the recycling of mantle volatiles in processes that affect habitability. The emergence of plate tectonics on Earth set the planet apart from others in our solar system allowing for the propagation of life, yet the fundamentals of how it all began remain unresolved. Present-day geophysical imaging of the deep mantle show anomalous chemical piles thought to originate from the beginnings of Earth. Recently, consensus has been reached that the chemical piles can impact, and be impacted by, plate tectonic processes. However, their interaction with mantle convection in a pre-plate tectonic early Earth is not well known. In this study, state of the art numerical experiments will be designed and implemented to offer the first investigation into what role deep chemical heterogeneities play in the initial breaking of the lithosphere (to initiate a form of plate tectonics). Furthermore, a numerical analysis into the evolution of temperature and mantle dynamics in the early Earth will be conducted to assess a range of geodynamic scenarios previously hypothesized. This fellowship is timely as it complements a number of recent developments in early Earth tectonics, numerical modelling, and in knowledge of thermo-chemical pile behaviour. ", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["749664"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KUNGLIGA TEKNISKA HOEGSKOLAN"], "EU_Contribution": ["EUR 173 857,20"], "Project_Title": ["Excellent lung cancer imaging and tumour identification using next generation computed tomography"], "Total_Cost": ["EUR 173 857,20"], "Country": ["Sweden"], "Project_ACR": ["EXCITING-CT"], "Technology_Description": "Lung cancer has the highest incidence and mortality rates of all cancers, and patient survival is strongly linked to early detection. Therefore, low-dose CT screening of high-risk individuals, the only method proven to improve survival, is now recommended by major health organisations. There are, however, concerns with the high rate of false positives and increased radiation exposure associated with screening. We propose to investigate the clinical benefits of spectral CT for lung nodule detection and characterisation. The unique, photon-counting, spectral silicon detector developed by the host group offer twice the resolution, no lower dose limit, reduced artefacts, and higher contrast sensitivity than current state-of-the-art. Our hypothesis is that the patient dose can be significantly reduced in both the detection and characterisation steps, and that the higher resolution will reduce false positives. The reduction in screening dose alone would prevent an estimated 15 cases of induced cancer per 10,000 individuals screened. Fewer false positives would then further reduce the dose through fewer follow-ups and characterisations, lower clinical costs and workload, and reduce patient distress. The fellowship would allow the researcher to benefit from the world-class research, close ties to commercial partners and strong international collaborations of the host, and the exceptional clinical expertise of the partner organisation. In particular, training in cutting-edge detector technology, novel image reconstruction techniques and management of patient studies would complement the researcher\u2019s strong background in medical physics and image analysis. The training, expected high-impact research and networking opportunities will strongly enhance the career prospects of the researcher, the outreach activities will give public awareness of the potential of spectral CT, and the expected clinical gain will benefit society at large, in particular future lung cancer patients.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Sweden"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["750564"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITY OF CYPRUS"], "EU_Contribution": ["EUR 221 446,80"], "Project_Title": ["'Sharing without Solidarity: Politics, Heritage and Pilgrimage in a Divided European Society'"], "Total_Cost": ["EUR 221 446,80"], "Country": ["Cyprus"], "Project_ACR": ["T.A.MA"], "Technology_Description": "The proposed project will explore how religion, politics and heritage intersect in a deeply divided European society, by examining the Christian-Orthodox shrine of Apostle Andreas, in the Turkish-occupied Karpass peninsula (Cyprus). The shrine is mainly visited by Greek-Cypriots and to a lesser degree by Turkish-Cypriots, and it is currently being restored by both communities with the involvement of the EU. Using semi-structured interviews with pilgrims and officials involved in the shrine\u2019s management and restoration, participant observation, and visual and archival research material, the study will look at (a) the attempts to restore the shrine, and (b) the revival of pilgrimages in conditions of ongoing division. The initial aim is to uncover symbolic, cultural, ethnic and political associations ascribed to the shrine and the pilgrimage by local and international actors. Examination of the shrine is also a powerful means through which to access past and present aspects of intercommunal relations. One original dimension of the proposed project is that it is one of the very few to study the institution of pilgrimage as a whole, looking at pilgrims, organizers, political actors and international organizations. This all-round perspective is appropriate to an analytical approach that, unusually, does not take religious motivation to be the default motivation for participation in the workings of a shrine, and it is necessary as a means of seeing whether and how different stakeholders articulate with each other in a situation of ongoing tension. This model of \u2018articulation\u2019 is intended to transcend simple dichotomies evident in the anthropological literature between \u2018communitas\u2019 (fellowship) and contestation in the operation of a shrine. Focusing on a pilgrimage site that is located in a divided country that is a member of the EU, the project has the potential to inform EU policy on heritage and conflict resolution, while benefiting the communities under study.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Cyprus"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["752103"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE PARIS DESCARTES"], "EU_Contribution": ["EUR 246 668,40"], "Project_Title": ["Next gEneration Sequence sTORage"], "Total_Cost": ["EUR 246 668,40"], "Country": ["France"], "Project_ACR": ["NESTOR"], "Technology_Description": "Sequential data are everywhere, from DNA sequences to astronomical light curves, and from aircraft engine monitoring data to the prices of stock options. Recent advances in various fields such as those of data storage, networking and sensing technologies, have allowed organizations to gather overwhelming amounts of sequential data at unprecedented speeds.", "To": ["2020-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["748945"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITEIT VAN AMSTERDAM", "UNIVERSITEIT VAN AMSTERDAM"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Quantifying Quantum Gravity Violations of Causality and the Equivalence Principle"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Netherlands", "Netherlands"], "Project_ACR": ["QUANTIVIOL"], "Technology_Description": "Quantum gravity must violate at least one of three principles at the foundations of physics: unitarity, causality, or the equivalence principle. Recent theoretical work on black holes has shown that such violations are not limited to extremely short distances, where quantum gravity effects are expected, but also occur at distances much larger than the Planck scale. This work has revealed a huge gap in our understanding: we have no working criterion for when quantum gravity violations of the usual laws of physics are important.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["725977"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN"], "EU_Contribution": ["EUR 171 460,80"], "Project_Title": ["Prebiotic Synthesis of Pyrimidine Nucleosides: New Insights into RNA Evolution"], "Total_Cost": ["EUR 171 460,80"], "Country": ["Germany"], "Project_ACR": ["PRENUCRNA"], "Technology_Description": "Understanding how life evolved on Earth is widely regarded as one of the most formidable challenges in modern science. The exploration of the mechanisms regarding the origin of life not only expands our understanding of natural sciences, but also provides new clues regarding the search for life forms and Earth-like conditions on planets other than our own. Ribonucleic acid (RNA) is widely regarded by the scientific community as the key molecule that gave rise to the origin of life. In order to support this \u201cRNA World\u201d hypothesis, scientists over the years have attempted to replicate the conditions present on the early-earth to afford nucleosides in a prebiotic manner. The lack of a uniform synthetic pathway affording canonical purine and pyrimidine nucleosides as well as non-canonical ones impedes our deeper understanding of the early evolution of RNA. Moreover, what has not been investigated in detail is the occurrence of a more primitive prebiotic molecule that might have evolved into RNA over the millennia. In this project, Dr. Okamura aims to study the prebiotic emergence of pyrimidine and pyrimidine-like nucleosides by developing a novel cyanoacetylurea pathway. This is expected to provide canonical as well as non-canonical pyrimidines under prebiotically plausible conditions. Using similar principles, novel pseudo-cyclic pyrimidines, inspired by the aforementioned pathway, will also be synthesized in order to examine their potential validity as candidates for primitive RNA. This project will provide new insight into the evolution of RNA as well as a deeper understanding of the origin of life. Moreover, it will aim to inspire novel approaches towards the European space exploration programs for the search of Earth-like conditions as well as life forms on other planets. This multidisciplinary field, where astrobiology meets prebiotic and nucleic acid chemistry will inspire and offer unique training to Dr. Okamura enabling him to embark on his own academic career.", "To": ["2019-05-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-06-01"], "Project_ID": ["752420"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["NATURAL HISTORY MUSEUM"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Evolution of the Cochlea and Hearing in Odontocetes"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ECHO"], "Technology_Description": "Toothed whales (Odontoceti) are a spectacular example of evolutionary adaptation, highly specialised apex predators and a key component of modern ocean ecosystems. The key innovation that has facilitated their evolutionary success is echolocation. Research into odontocete hearing has so far been biased towards physiological experiments and auditory pathway identification; quantitative studies on the cochlea are lacking, despite its critical role in audition. I will fill this gap in knowledge of the cochlea in cetaceans by: (1) quantifying differences in the morphology of odontocete cochlea through the application of cutting-edge scanning, visualisation and quantitative analytical techniques (e.g. 3D geometric morphometrics) to gather in depth data of all features of a fully representative range of odontocete cochlea; (2) testing through statistical analysis whether these differences correlate with, or are driven by, factors such as diet, behaviour or auditory sensitivity; (3) incorporating fossil taxa to pinpoint the timing of the evolution of echolocation; and (4) identifying convergent evolution of specialised high frequency hearing in river dolphins using novel methods for testing and quantifying morphological convergence. This project will create the most comprehensive data set of odontocete inner ear models ever compiled and will mark a major advance in the understanding of cetacean sensory evolution, providing profound insights into how this enigmatic group of marine mammals came to dominate the oceans - making sense of a sixth sense. The data gathered will be made openly available to other researchers.", "To": ["2019-10-01, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2017-10-02"], "Project_ID": ["748167"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["FUNDACIO CENTRE DE REGULACIO GENOMICA"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["Functional dissection of core spliceosomal mutations causing Retinitis Pigmentosa."], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["SpliceCore"], "Technology_Description": "More than 95% of human genes undergo pre-mRNA splicing, and alternative splicing of mRNA precursors represents a prevalent mode of gene regulation. Errors in this process are often the origin of of disorders. Most of splicing-related diseases are caused by perturbation in pre-mRNA transcripts which lead to their aberrant processing. Interestingly, a fraction of mutations affecting directly splicing factors, including core spliceosomal components, has been linked to a group of pathologies. Particularly intriguing are variants of the key spliceosomal subcomplex U4/5/6 tri-snRNP, associated with Retinitis Pigmentosa. Why these mutations lead to highly tissue-specific phenotypes, rather than general toxicity cause by a global block in splicing, remain unexplained. The proposed research aims to increase our understanding of the molecular mechanisms underlying the effects of these mutations and shed light on the basis of the disease. To functionally dissect these variants, I will combine spliceosomal network approaches (I) with genome-wide transcriptome analysis (II) and detailed biochemical and structural studies (III). Mechanistic insights derived from these analyses will help to identify transcripts that are predominantly sensitive to these mutations and that could be behind their pathogenic effects (IV). This work will allow us to better understand the function of key splicing factors, as well as the basis for their effects on splice site selection and their contributions to Retinitis Pigmentosa pathology.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-04-01"], "Project_ID": ["747488"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["THE HEBREW UNIVERSITY OF JERUSALEM", "THE HEBREW UNIVERSITY OF JERUSALEM"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Elucidating the Role of Enhancer Methylation Variation in Cancer and Developing Enhancer-based Markers and Targets for Precision Medicine"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Israel", "Israel"], "Project_ACR": ["ONCOmetENHANCERS"], "Technology_Description": "Cancer is a growing medical problem which genetic and environmental basis is not clearly understood. Massive efforts over the last decade have identified differences in cancer gene expression that cannot be explained by coding sequences or promoter variations, whereas the effect of transcriptional enhancers remains unclear due to the lack of an effective way to link enhancers with their controlled genes. Recently, we discovered a class of inter-tumor, inter-patient DNA methylation variations in putative enhancers that predict changes in gene expression levels with much greater power than promoter or sequence analyses. The overall goal of this proposal is to determine if changes in enhancer methylation form part of the genomic basis of cancer. Our aim is to elucidate methylation-influenced disease regulatory circuits that affect cancer driver and risk genes and may ultimately serve as markers for disease progression and drug response. Utilizing a new genomic methodology, which allows systematic prediction and verification of gene-enhancer pairing, I will test the above hypothesis in two disease models: breast cancer and glioblastoma. I will methodologically assess numerous potential enhancers across the disease genomes and explore the effects of genetic and epigenetic mutations and variations at these sites. Informative sites will then be evaluated as markers of gene expression level in tumor biopsies. Ultimately, I will apply novel tools to manipulate selected enhancers genetically and epigenetically, thus investigating the causal relationships between enhancer methylation and gene expression, and assessing the potential for tuning gene expression levels by enhancer methylation modification. This study may transform our understanding of the mechanisms underlying disease predisposition, determine the regulatory circuits of key disease genes, lead to improved diagnosis and predictive abilities, and may pave the way for precision epigenetic therapy.", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["724803"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Mapping Nanoscale Charge Separation at Heterojunctions with Ultrafast Electroabsorption Microscopy"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["NanoEAscopy"], "Technology_Description": "Nanostructured electronic materials e.g. organic semiconductors (OSCs) and 2D semiconductors offer great promise for applications in optoelectronic (OE) devices, such as photovoltaics (PVs), light emitting diodes (LEDs) and photodetectors. The primary photoexcitations in both OSCs and 2D semiconductors are strongly bound excitons, quasiparticles of electrons and hole bound by the Coulomb interaction. Three aspects of these materials stand out when attempting to study photophysics of these materials. (1) Many of the crucial OE process in these systems occur at heterojunctions between p- and n-type materials, where charges recombine to form excitons and excitons dissociate to form charges. (2) The timescale for many such process is sub-ps, and charge transfer and charge separation (CS) can occur on sub-100fs timescales. (3) thin films made of these materials possess spatial inhomogeneity on \u00b5m and sub-\u00b5m length scales, due to variations in molecular packing, crystallinity and phase segregation in OSCs and due to lattice defects and variation in surface passivation and strain in 2D materials. No currently available technique has the ability to spatially correlate transient spectroscopic data with local molecular structure and composition. In order to do this, we will develop a new platform to directly image CS with sub-10fs time-resolution with sub-\u00b5m spatial resolution. Recent advances in pump-probe microscopy and ultrafast Electro-Absorption (EA) spectroscopy in the host\u2019s group will be combined with the applicant\u2019s expertise with optical microscopes and advanced data analysis methods to detect and quantify inhomogeneity. Novel analysis methods combined with an ultrafast EA pump-probe microscopy will allow for correlation of transient spectroscopic data with local molecular structure and composition. This will lead us to elucidate how CS is controlled by local properties such as molecular packing and crystallinity in OSCs and defect sites etc. in 2D semiconductors.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["748050"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE DE RENNES I", "UNIVERSITE DE RENNES I"], "EU_Contribution": ["EUR 1 415 506"], "Project_Title": ["Fluorescent-based innovative measure in thin liquid films: A way to understand stability and energy dissipation in foams and emulsions"], "Total_Cost": ["EUR 1 415 506"], "Country": ["France", "France"], "Project_ACR": ["DISFILM"], "Technology_Description": "Nobody knows why a soap bubble collapses. When the liquid film forming the bubble, stabilised by surfactants, becomes too thin, it collapses. This seemingly simple problem, ruled by the classical laws of fluid mechanics and of statistical physics, is still a challenge for the physicist. The rupture criteria based on a stability analysis in the vicinity of the film equilibrium state fail to reproduce the observations. However the film ruptures in a foam obey some simple phenomenological laws, which suggest that underlying fundamental laws exist and wait to be determined. The state-of-the-art conjecture is that ruptures are related to hydrodynamical processes in the films, a field in which I have now an international leadership. Recent experimental data I obtained open the possibility to address this question using a fully non-linear approach in the far from equilibrium regime. In this aim, DISFILM will develop an innovative technique to measure the interface velocity and surfactant concentration, based on the use of fluorescent surfactants. The risk relies in the adaptation to dynamical conditions of advanced optical techniques. These quantities have never been measured on flowing interfaces yet, and my technique will be an important breakthrough in the field of free interface flows in presence of surfactants. A set-up will be designed to reproduce on few thin films the deformations occurring in a foam sample. The dynamical path leading to the rupture of the film will be identified and modelled. The results obtained on an isolated film will be implemented to predict the 3D foam stability and the approach will be extended to emulsions. Foams and emulsions are widely used in industry and most of the stability issues have been solved. Nevertheless, most of the industrial formulations must currently be modified in order to use green surfactants. This adaptation will be extremely more efficient and possible with the results of DISFILM as a guideline.", "To": ["2022-08-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["725094"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER"], "EU_Contribution": ["EUR 159 460,80"], "Project_Title": ["Saline Fluids in the Mantle - Experimental Investigation of Their Role in Diamond Formation and Kimberlite Magmatism"], "Total_Cost": ["EUR 159 460,80"], "Country": ["Germany"], "Project_ACR": ["SalFluMa"], "Technology_Description": "The majority of natural diamonds that have great economic importance for the gem industry are formed at great depth beneath old continents in the subcontinental lithospheric mantle (SCLM). The main carrier of these diamonds are kimberlites, deep volcanic rocks that transport fragments of the SCLM to the Earth\u2019s surface. Both diamond formation and kimberlite genesis are still heavily debated processes in the Geosciences. Growing evidence from natural samples, such as fluid inclusions in diamonds, suggests that chloride-bearing fluids may play an important role in diamond formation and possibly in kimberlite generation. These saline fluids are envisaged to percolate into the SCLM from slabs of oceanic crust that are subducted underneath the continents.", "To": ["2020-01-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-RI - RI \u2013 Reintegration panel"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2018-02-01"], "Project_ID": ["746518"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["TEL AVIV UNIVERSITY", "TEL AVIV UNIVERSITY"], "EU_Contribution": ["EUR 2 000 000"], "Project_Title": ["Stability and dynamics at different spatial scales: From physiology to Alzheimer's degeneration"], "Total_Cost": ["EUR 2 000 000"], "Country": ["Israel", "Israel"], "Project_ACR": ["MacroStability"], "Technology_Description": "How neuronal circuits maintain the balance between stability and plasticity in a constantly changing environment remains one of the most fundamental questions in neuroscience. Empirical and theoretical studies suggest that homeostatic negative feedback mechanisms operate to stabilize the function of a system at a set point level of activity. While extensive research uncovered diverse homeostatic mechanisms that maintain activity of neural circuits at extended timescales, several key questions remain open. First, what are the basic principles and the molecular machinery underlying invariant population dynamics of neural circuits, composed from intrinsically unstable activity patterns of individual neurons? Second, is homeostatic regulation compromised in Alzheimer's disease (AD) and do homeostatic failures lead to aberrant brain activity and memory decline, the overlapping phenotypes of AD and many other distinct neurodegenerative disorders? And finally, how do homeostatic systems operate in vivo under experience-dependent changes in firing rates and patterns? ", "To": ["2022-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["Israel"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2017-10-01"], "Project_ID": ["724866"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 269 857,80"], "Project_Title": ["Linguistic Illusions in Children with Down Syndrome, Specific Language Impairment and Typical Language Development"], "Total_Cost": ["EUR 269 857,80"], "Country": ["United Kingdom"], "Project_ACR": ["LINGUISTIC ILLUSIONS"], "Technology_Description": "This project investigates the acquisition of grammar in children with Down syndrome (DS), Specific language Impairment (SLI) and typical language development (TLD) between the ages of 2 and 12, speaking African American Vernacular English (AAVE) and Southern English (SE). Similarities and differences will be compared between the three populations to determine whether the reduced use of inflectional marking in AAVE speaking children is the result of linguistic illusions, conditioned by factors external to morphosyntax (i.e dialectal particularities). ", "To": ["2020-08-20, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-08-21"], "Project_ID": ["749360"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITE DE RENNES I"], "EU_Contribution": ["EUR 173 076"], "Project_Title": ["Geophysical Signature of Subsurface Reactive Mixing"], "Total_Cost": ["EUR 173 076"], "Country": ["France"], "Project_ACR": ["GeoElectricMixing"], "Technology_Description": "Subsurface reactive processes play a key role in dictating the evolution of subsurface environments, their interaction with surface water bodies and the migration and remediation of transported contaminants. In particular reactive hot spots tend to concentrate in mixing fronts between fluids of different compositions, such as recently infiltrated/injected fluids and resident groundwater, which develop in a range of situations, including CO2 sequestration operations and geothermal systems, contaminant remediation operations, and reactive hyporheic zones beneath rivers. Our understanding of the development and temporal dynamics of these hotspots is currently hampered by the limited sampling offered by boreholes. Recent breakthroughs in geoelectrics may however profoundly change our vision of these phenomena by providing non-invasive techniques with high sensitivity to many geological processes. GeoElectricMixing will hence develop a novel approach to investigate the temporal dynamics of reactive mixing processes from Complex Impedance and Self Potential signals. The coupling of reactive mixing and geoelectrics will be quantified and upscaled by integrating charge transport and polarization phenomena in a new modeling framework, recently developed by the host to predict the spatial distribution of chemical species and reaction rates across mixing fronts (WP1). Dedicated experiments will then be designed by integrating electrodes in a novel millifluidic setup to monitor jointly the temporal evolution of geoelectrical parameters and the spatial distribution of concentrations and reactions rate in a reactive mixing front progressing through the cell (WP2). GeoElectricMixing is thus expected to open a new window on subsurface reactive mixing phenomena, expanding our capacities to detect and quantify these processes in situ, and thus providing critical data to unlock current open questions on the dynamics of mixing processes and their role in reaction enhancement.", "To": ["2019-03-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["France"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-04-01"], "Project_ID": ["752773"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["KATHOLIEKE UNIVERSITEIT LEUVEN"], "EU_Contribution": ["EUR 172 800"], "Project_Title": ["Microbes in the city: a metagenomic trait-based analysis of microbial metacommunity structure along urbanization gradients"], "Total_Cost": ["EUR 172 800"], "Country": ["Belgium"], "Project_ACR": ["MicroCity"], "Technology_Description": "Human induced environmental gradients have a strong effect on biodiversity and ecosystem functioning. Despite the valuable ecosystem services (such as biogeochemical cycling and xenobiotic degradation) provided by microbial communities, environmental conservation policies usually neglect microbial diversity. This can be in part attributed to our poor understanding of microbial community responses to anthropogenic influences in natural landscapes. Urban ecosystems are key examples of environments that are strongly impacted by anthropogenic activity. In addition to our need to understand how microbial communities respond to urbanization, urbanization gradients are also excellent model systems to study how the taxonomic and functional diversity and composition of microbial communities respond to anthropogenic stress in general.", "To": ["2017-04-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Belgium"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-05-01"], "Project_ID": ["655159"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Effectiveness of Terrestrial Protected Areas in Reducing Human Pressure"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["PRESSURE"], "Technology_Description": "Human impacts on nature have led to massive biodiversity declines. Protected areas (PAs) have been suggested as one of the most important tools to reduce human pressure and protect biodiversity. In this project I will advance our understanding of the effectiveness of terrestrial PAs in reducing human pressure and improve current knowledge on how to measure human pressure, by specifically addressing three objectives: 1) To understand how management quality affects PAs ability to reduce human pressure, 2) To reconciling remote sensed maps of human pressure with field observation of the impact of human threats, and 3) To improve existing maps of human pressure by including data of key threats to biodiversity (e.g. natural resource use and invasive species). The foundation of the project will be the Temporal Human Pressure Index (e.g. a temporal Human Footprint), the World Database of Protected Areas, and a global database on Management. The three objectives will apply different state-of-the-art statistical approaches including propensity matching and general linear mixed effects models to achieve these ambitious objectives. The project is expected to lead to three high impact peer-reviewed papers as well as min two popular science papers, and one policy brief. The project will help me develop new data and skills instrumental to achieving my career goals in academia after the fellowship. I will be hosted in the conservation group at the University of Cambridge, under supervision of Professor Andrew Balmford who is one of the world\u2019s leading conservation scientist and an expert on how to understand human pressure in relation to biodiversity. Professor Neil Burgess will be my supervisor while seconded at WCMC. He is a world leading expert on management effectiveness and has years of experience working on pressure and PAs. This proposal represents a frontier in conservation science and is of very high relevance to the EU and global conservation policy.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["706784"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITEIT UTRECHT"], "EU_Contribution": ["EUR 177 598,80"], "Project_Title": ["New generation of chimeric TLR2-NOD agonist compounds for vaccine adjuvants"], "Total_Cost": ["EUR 177 598,80"], "Country": ["Netherlands"], "Project_ACR": ["FusionPAMPs"], "Technology_Description": "New vaccine modalities need to be developed that can activate more potently the immune system, in this regard, adjuvants augment adaptive immune responses and can improve vaccine performance. Aluminium salt (alum) is the most commonly used adjuvant for human vaccination. However, it drives primarily TH2-effector responses and is not effective for vaccines that target mucosal surfaces. Thus, safe and potent adjuvants need to be developed that can increase and direct vaccine-specific immunity. Recent advances in our understanding of innate immune responses are providing opportunities to design better adjuvants. The innate immune system senses microbes through pattern-recognition receptors (PPRs), which include the Toll-like receptors (TLRs), and intracellular NOD-like receptors (NLRs) and C-type lectin-like (CTLs) receptors that are expressed by immune cells. Activation of these receptors leads to the production of cytokines that provide early defences during infection. Cytokines also regulate adaptive immunity by controlling the quantity and quality of B and T cell activation, which in turn results in protective immune responses to pathogens. Pathogen-associated molecular patterns (PAMPs) such as lipopolysaccharides, lipopeptides, and peptidoglycan fragments can activate PPRs and are attractive compounds for the development of new adjuvant. Although during microbial infection many different PRRs are activated, almost all adjuvants that are being developed rely on the stimulation of a single PRR. In this project, we propose that compound adjuvants derived by the covalent linking of two PAMPs (fusion PAMPs), for example, TLR2 and NOD agonists, will ensure that immune cells are being exposed to both, resulting in efficient cross talk of signal transduction pathways and in synergistic immune activation. If so, chimeric immune modulators (fusion PAMPs) can be employed at lower adjuvant concentrations, thereby minimizing unwanted side effects.", "To": ["2019-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Netherlands"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-05-01"], "Project_ID": ["749719"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["JOHN INNES CENTRE", "JOHN INNES CENTRE"], "EU_Contribution": ["EUR 2 749 962"], "Project_Title": ["Quantitative analysis of DNA methylation maintenance within chromatin"], "Total_Cost": ["EUR 2 749 962"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["MaintainMeth"], "Technology_Description": "Cytosine methylation is a chemical modification that is precisely copied when DNA is replicated. Because methylation can regulate gene expression, accurate reproduction of DNA methylation patterns is essential for plant and animal development and for human health. The enzymes that maintain DNA methylation have to work within chromatin, and particularly to contend with nucleosomes \u2013 tight complexes of DNA and histone proteins. How methylation of nucleosomal DNA is maintained remains unknown, and even the simple matter of whether nucleosomes hinder or promote methylation is controversial.", "To": ["2022-03-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-2016-COG - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Research Organisations", "Research Organisations"], "From": ["2017-04-01"], "Project_ID": ["725746"], "Call_for_Proposal": ["ERC-2016-COG"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Algorithmic Containment of Threats in Graphs, Networks or Webs"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ACTING-NOW"], "Technology_Description": "The project is about the security of networks, and how to select the best containing actions to perform when a network is threatened. Network security is a major concern for Europe in the guise of at least three threats: attacks on computer networks and related infrastructure; diseases spreading in networks consisting of people, livestock, crops or wildlife; and the spread of fires in forests or buildings. The project brings together an experienced researcher with a successful track record in \u201cthe firefighter problem\u201d (which models the general network security problem), a supervisor with complementary expertise and world-leading research record in multi-objective optimization, a host organization with expertise and leading research groups in (i) Security, (ii) Randomized, heuristic optimization (from theory to industrial exploitation) and (iii) Human-Computer Interaction. Two non-academic secondment partners strengthen this team still further, bringing in industry-scale optimization experience (Noesis Solutions), and a long track record of advising for fire safety to major infrastructure projects including to the military (Lee Anderson). The experienced researcher will use the training and mobility afforded by this complementary partnership to further the impact of his research on European security, benefit from skills training in industrial exploitation and on offering policy advice, and learn a range of additional academic and non-academic skills from participating in the training of young researchers. Scientific results of the project include new, effective computational methods achieving better results in practical applications mentioned above. Theoretical understanding of spreading emergencies in graphs will be useful in fundamental research in other fields, for example, in medicine in research aimed at utilizing the knowledge about contacts in the population for understanding how disease traits (such as the transmission rate and the infectious period) evolve.", "To": ["2018-09-11, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-12"], "Project_ID": ["704330"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["THE UNIVERSITY OF EXETER"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Regulating Umbilical Cord Blood Biobanking in Europe"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["REGUCB"], "Technology_Description": "The research proposed for this fellowship is a study of the establishment of national and European regulation on Umbilical Cord Blood (UCB) biobanking in a comparative perspective (the UK, Germany, France, Italy and Spain) and with an in-depth analysis of the implementation of regulation in the everyday practice of UCB practi-tioners, through a bi-national comparison in the UK and Italy. The first scientific aim is to offer an empirically grounded understanding of how regulations and their practical implementation influence the conducting of biosci-entific research and shape the structuring of different bioeconomy regimes in UCB science and clinical applica-tion. The second scientific aim is to contribute to the field of Science and Technology Studies (STS) by develop-ing an analytical approach combining macro-analysis on policy-making and regulations with meso- and micro-level analyses on the practical accomplishment of enacting regulations in everyday research practices, for offering a more comprehensive understanding of governance and policy-making in the field of biomedicine which inte-grate the role of structural factors with that of the agency of actors involved. Given the importance assigned by the European Union to the development of stem cell research and the coordination of biobanks, the proposed research aims also to offer useful policy suggestions for improving the harmonization and optimization of the EU circuit of supply of UCB units for biological research and medical applications. I will diffuse to practitioners and regulators the findings of the research related to the comparative analysis on national regulations, on the ways in which these interact with the EU directives and on how practitioners manage and enact compliance with national regulations, international directives and the exigencies of the global circulations of biomedical objects, standards, and proto-cols in biobanking.", "To": ["2017-09-30, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-10-01"], "Project_ID": ["657361"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["BCBL BASQUE CENTER ON COGNITION BRAIN AND LANGUAGE"], "EU_Contribution": ["EUR 158 121,60"], "Project_Title": ["The time-course of visual, orthographic, phonological and semantic information during written word processing in skilled deaf readers: evidence from eye movements and ERPs"], "Total_Cost": ["EUR 158 121,60"], "Country": ["Spain"], "Project_ACR": ["TIME COURSE"], "Technology_Description": "Learning to read is a great challenge for deaf children due to their limited access to the sounds andlimited knowledge of the language they learn to read. Deaf adults\u2019illiteracy levels aremuch higher than that of their hearing peers, but some deaf individuals can and do become skilled readers, though in a qualitatively different way than typically observed in hearing readers. New evidence shows that relative to skilled hearing readers (SKH), deaf readers do not activate phonological codes, but activate orthographic codes and show greater use of semantic informationduring word reading. Eye movement data shows that skilled deaf readers (SKD) skip words more often, and refixate words less often than SKHreaders do. In other words, SKDreaders are more efficient at processing words accurately within a single fixation than SKHreaders are, and this may be in part explained by 1) faster processing of visual information, 2) more direct connections between orthography and semantics, or 3) a combination of these two factors. This has been termed the word processing efficiency (WPE) hypothesis and the hypothesis predicts that SKD readers will show earlier activation of orthographic codes, no phonological activation, and thus faster access to semantic codes compared to SKH readers. I will test this hypothesis by investigating and comparing the time-course of word processing in SKDand SKHreaders, by 1) observing participants\u2019 eye movements during reading to determine the earliest point of activation of parafoveal visual, orthographic, phonological, and semantic codes, and 2)assessing the neural underpinnings of the WPE hypothesis with respect to the timing and types of codes with ERP measures. The results will lead to empirically tested solutions for the reading development of deaf children that are not based on how reading develops in children who can hear and will lead to more effective reading instruction for deaf children to increase their functional literacy.", "To": ["2019-04-30, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Spain"], "Activity": ["Research Organisations"], "From": ["2017-05-01"], "Project_ID": ["704005"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE", "MOSAIQUES DIAGNOSTICS GMBH", "IDRYMA IATROVIOLOGIKON EREUNON AKADEMIAS ATHINON", "EMERGENTEC BIODEVELOPMENT GMBH", "HYBRIDSTAT PREDICTIVE ANALYTICS OE"], "EU_Contribution": ["EUR 387 000"], "Project_Title": ["PRoteome-based assessment of vascular disease for the Establishment of a Translational REsearch plATform"], "Total_Cost": ["EUR 387 000"], "Country": ["France", "Germany", "Greece", "Austria", "Greece"], "Project_ACR": ["PRETREAT"], "Technology_Description": "Cardiovascular disease (VD) is the leading cause of mortality and morbidity in Europe and worldwide. The objective of the PRETREAT consortium is to generate a joint SME/academic European preclinical platform for providing services for detection of VD and drug development. This platform will combine the use of urinary and/or blood peptidomics in humans and in preclinical animal models of VD, together with bioinformatics and systems biology, in order to better detect, stratify and decipher the molecular mechanisms of VD, develop new animal models with high similarity to human disease, and provide new tools for obtaining information on novel drug targets.", "To": ["2019-12-31, Grant Agreement terminated"], "Meta": [""], "Topic_s": ["MSCA-RISE-2015 - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Funding_scheme": ["MSCA-RISE - Marie Sk\u0142odowska-Curie Research and Innovation Staff Exchange (RISE)"], "Coordinated_in": ["France"], "Activity": ["Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Research Organisations", "Private for-profit entities (excluding Higher or Secondary Education Establishments)", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2016-01-01"], "Project_ID": ["690966"], "Call_for_Proposal": ["H2020-MSCA-RISE-2015"]}, -{"Partners": ["HERIOT-WATT UNIVERSITY"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["ANALYSIS OF RC STRUCTURES EMPLOYING NEURAL NETWORKS"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ARCSENN"], "Technology_Description": "The primary objective of the proposed project is to develop a radically new structural analysis procedure capable of accurately predicting the nonlinear behaviour of reinforced concrete structures. The proposed approach will be developed within the Soft Computing framework and as a result will require significantly less computational resources than those of more traditional methods of structural analysis. The proposed procedure will simulate each RC element, the beam-column joints included, with a single neural network, which has first to be appropriately trained. The training process will be based on the combined use of published test data, numerical predictions obtained from nonlinear finite-element analyses and the predicted behaviour of published physical models of RC structural elements at their ultimate limit state. In order to model intricate structures, the individual Neural Networks will be combined through a new solution strategy so as to provide a representative model of the structure considered. The stability and robustness of the proposed structural analysis method, as well as the validity and objectivity of its predictions, will be ensured through a comparative study of the predicted behaviour of RC frames with its counterparts established experimentally and numerically via nonlinear finite element analysis. Throughout these studies, attention will be focussed on identifying parameters affecting the overall structural response of RC frames (such as the effect of crack-formation within the joint regions) as well as their implications on practical structural analysis and design. Overall, the proposed work will lead to a stable, robust and computationally efficient numerical procedure capable of realistically and objectively predicting the nonlinear response of RC structures and suitable, not only for research and practical applications, but also for solving design optimization and reliability problems which require extensive parametric investigations.", "To": ["2017-08-31, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["660545"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["HERIOT-WATT UNIVERSITY"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Climate-resilient pathways for the development of concrete infrastructure: adaptation, mitigation and sustainability"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["ClimatCon"], "Technology_Description": "Climate change is one of the key challenges facing the human race in the 21st century. To respond to this challenge new approaches to sustainable development combining mitigation and adaptation, which are referred to as climate-resilient pathways, are needed. The development of such approaches is one of the high priority areas of modern day research that will be addressed in the proposed action in the context of concrete infrastructure. The action aims to develop a comprehensive method based on an integration of the Life-Cycle Assessment (LCA) and Life-Cycle Cost Analysis (LCCA) techniques for the evaluation of the whole life performance of reinforced concrete (RC) structures subjected to carbonation in conditions of climate change. To achieve this both experimental studies and numerical modelling are planned to be carried out. The method will take into account both adaptation and mitigation measures and due to numerous uncertainties involved in such analysis be based on a probabilistic approach. It will be applied to several case studies (i.e., typical RC members located in different climatic conditions) to examine the sustainability performance of different concrete types (traditional and \u2018green\u2019 with blended cements) and repair techniques. The method and other results obtained in the action will provide strong support for decision making regarding the sustainable development of concrete infrastructure.", "To": ["2017-08-02, closed project |"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-08-03"], "Project_ID": ["658475"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["LANCASTER UNIVERSITY", "THE UNIVERSITY OF NOTTINGHAM", "THE UNIVERSITY OF SHEFFIELD", "UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK", "III-V LAB", "UNIVERSIDAD DE CADIZ", "UNIVERSITE DE MONTPELLIER", "UNIVERSITE MONTPELLIER 2 SCIENCES ET TECHNIQUES", "UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA", "PHILIPPS UNIVERSITAET MARBURG", "SGENIA SOLUCIONES SL"], "EU_Contribution": ["EUR 3 947 500,44"], "Project_Title": ["Postgraduate Research on Dilute Metamorphic Nanostructures and Metamaterials in Semiconductor Photonics"], "Total_Cost": ["EUR 3 947 500,44"], "Country": ["United Kingdom", "United Kingdom", "United Kingdom", "Ireland", "France", "Spain", "France", "France", "Italy", "Germany", "Spain"], "Project_ACR": ["PROMIS"], "Technology_Description": "Photonics, nanotechnology, advanced materials, and advanced manufacturing technologies have been identified as key enabling technologies (KETs) for the EU. Today the photonics global market alone is around \u20ac300 billion and Europe has established a strong position with a total share of 20%, directly employing about 290,000 people. However, the shortage of sufficient skilled labour and entrepreneurs capable of handling the highly multi-disciplinary nature of KETs remains a major problem in the EU. Tailoring of semiconductors at the nanoscale is an important enabling technology for a wide range of photonics and electronics applications in diverse areas. In the training network proposed here, a cohort of 15 early stage researchers will be trained in the full range of skills required for a career in photonics, including materials growth, device fabrication, characterisation, design, theory, and commercialisation. A carefully-chosen, well-balanced consortium of 8 academic partners, 2 full industry partners and 7 associated partners are well placed to provide the training in these skills, with European and worldwide reputations as leaders in each field. These skills will be developed within four burgeoning research areas; Semiconductor Metamaterials & Plasmonics, Dilute Nitride semiconductor nanostructures, Hydrogenated Semiconductors and Metamorphic structures. The outcomes of this enabling fundamental research are well focused to deliver advances in sources for secure communications, sensitive detectors for security applications, more efficient solar cells for energy generation, LEDs and sensors for environmental gas and bio-sensing. Each researcher will experience both academic and commercial environments thanks to the strong industrial involvement, resulting in multi-skilled, industry-focused graduates. PROMIS therefore directly addresses the need for additional skilled photonics professionals, as identified by the European Technology Platform, Photonics21.", "To": ["2018-12-31, ongoing project |"], "Meta": [""], "Topic_s": ["MSCA-ITN-2014-ETN - Marie Sk\u0142odowska-Curie Innovative Training Networks (ITN-ETN)"], "Funding_scheme": ["MSCA-ITN-ETN - European Training Networks"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Research Organisations", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments", "Private for-profit entities (excluding Higher or Secondary Education Establishments)"], "From": ["2015-01-01"], "Project_ID": ["641899"], "Call_for_Proposal": ["H2020-MSCA-ITN-2014"]}, -{"Partners": ["THE UNIVERSITY OF BIRMINGHAM"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["Epigenetic mechanisms underlying the influence of paternal drug experience on offspring behavior"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["EPOFFSPRING"], "Technology_Description": "The idea of transmitting paternal environmental impact across generations has been indicated and described in studies across species, but the mechanism is still unclear. The overall aim of the project is to test whether H3K27me3, a type of epigenetic modification on histone 3 [1], is involved in transmitting environmental impact across generation to influence the behavior of offspring. With a behavioral neuroscience background, the experienced research (ER) will apply his expertise in high throughput behavioral assay and combine techniques he will learn from the host lab, including epigenetic profiling, NGS, targeted epigenome editing and computational analysis to address specifically whether paternal drug experience influence offspring behavior via modifying H3K27me3 on dopamine-related genes that are involved in various behaviors [2]. Besides advancing our understanding of the importance and mechanism of paternal inheritance and the role of epigenetics in general, this project will also further extend zebrafish as a model in studying cross-generational transmission of environmental experience by combining multidisciplinary techniques. The trainings ER will be beneficial and essential for his future goal to study epigenetic mechanisms underlying physiology and pathology of brain.", "To": ["2019-02-28, Grant Agreement terminated |"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-03-01"], "Project_ID": ["753976"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["UNIVERSITAET HAMBURG", "THE REGENTS OF THE UNIVERSITY OF CALIFORNIA"], "EU_Contribution": ["EUR 239 860,80"], "Project_Title": ["Room temperature stabilization and all-electrical manipulation of chiral spin structures in metallic multilayers"], "Total_Cost": ["EUR 239 860,80"], "Country": ["Germany", "United States"], "Project_ACR": ["SKDWONTRACK"], "Technology_Description": "The constantly increasing energy consumption associated with the functioning of micro-electronic devices calls for the design of more energy efficient technologies. While semiconductor technologies have reached their intrinsic limitations, spintronics offers a new path towards the design of memory and logic devices with high density and low power consumption. However, present spintronic devices such as magnetic-RAMs still suffer from high current density requirements. ", "To": ["2020-12-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2016 - Individual Fellowships"], "Funding_scheme": ["MSCA-IF-GF - Global Fellowships"], "Coordinated_in": ["Germany"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2018-01-01"], "Project_ID": ["748006"], "Call_for_Proposal": ["H2020-MSCA-IF-2016"]}, -{"Partners": ["ANKARA UNIVERSITESI", "ANKARA BUYUKSEHIR BELEDIYE BASKANLIGINA"], "EU_Contribution": ["EUR 131 260"], "Project_Title": ["Life is Science, Science is Life: LET'S DO THE SCIENCE!"], "Total_Cost": ["EUR 353 525"], "Country": ["Turkey", "Turkey"], "Project_ACR": ["Let's Do The Science"], "Technology_Description": "Through the project, it is aimed to show public that researchers are most likely with them. They work in a wide range of topic but the common base for all areas is scientific point of view. It is planned to organize an event including at least 200 different interactive scientific activities from wide range of scientific disciplines, opening universities laboratories to public, organizing number of meetings and workshops, conferences, edutainment facilities, seminars and entertainment activities related to science subjects, observing and discussing ideas of public about science and hot topics of their life related to science and EU. ", "To": ["2015-11-30, closed project"], "Meta": [""], "Topic_s": ["MSCA-NIGHT-2014 - European Researchers' Night (NIGHT)"], "Funding_scheme": ["CSA - Coordination and support action"], "Coordinated_in": ["Turkey"], "Activity": ["Higher or Secondary Education Establishments", "Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)"], "From": ["2014-05-01"], "Project_ID": ["633256"], "Call_for_Proposal": ["H2020-MSCA-NIGHT-2014"]}, -{"Partners": ["GOLDSMITHS' COLLEGE"], "EU_Contribution": ["EUR 195 454,80"], "Project_Title": ["The Rise of Neoliberal Feminism"], "Total_Cost": ["EUR 195 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["RNF"], "Technology_Description": "Focusing on neoliberalism's emergent feminist discourse in the UK and the US, I aim to provide a multi-dimensional theorization of this phenomenon. Two central questions inform this project: 1) Why does neoliberalism need feminism at this particular historical juncture in order to reinforce its hegemony? and 2) How and in what ways do certain themes of feminism lend themselves to the neoliberal project? Working on the seams of feminist theory, cultural studies and sociology, I will embark on a comparative study, examining one key but neglected site of neoliberalism's adoption of feminism: the discourse of a happy work-family balance. In order to accomplish this, I will employ a multidisciplinary methodological approach, combining textual and discourse analysis, qualitative data analysis and intersectional theorizing. My premise is that the resurgence of the work-family balance, which is being articulated as a feminist ideal, is the site through which the contemporary entanglement of feminism and neoliberalism is most clearly articulated. RNF therefore has four main interrelated objectives: to map the current resurgence of the work-family balance discourse in the mainstream print media in the UK and the US; to uncover the racial and economic underpinnings of this balance discourse; to analyse the new feminist subject this discourse is creating; and, finally, to build a theoretical framework that not only helps to explain why neoliberalism needs feminism at this historical juncture, but one that can help account for other contemporary alignments between feminism and neo-conservative and neoliberal projects in the broader European and Western context.", "To": ["2018-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-09-01"], "Project_ID": ["704010"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI FERRARA"], "EU_Contribution": ["EUR 168 277,20"], "Project_Title": ["Advanced devices for the Reduction of CArbon DIoxide and Artificial photosynthesis"], "Total_Cost": ["EUR 168 277,20"], "Country": ["Italy"], "Project_ACR": ["ARCADIA"], "Technology_Description": "The ARCADIA project will focus on building artificial photosynthetic devices (or photoelectrochemical cells), with the aim of producing alternative fuels exploiting renewable energy sources (namely sunlight). The key strategy will involve the development of photoelectrodes able to perform the water oxidation (at the anode) and the carbon dioxide reduction (at the cathode), and their further assembly in a standalone set-up (i.e. requiring no other energy source, but sunlight). Thus, ARCADIA will contribute to the abatement of the atmospheric anthropogenic emissions of the greenhouse gas CO2 by its exploitation as a renewable carbon feedstock to obtain clean fuels and value-added chemicals as the target products.", "To": ["2018-04-30, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-05-01"], "Project_ID": ["705723"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["HERIOT-WATT UNIVERSITY"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Scattering and Amplification of fundamental photonic-hydrodynamic excitations in Kerr non-linear media"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["SOUNDCONE"], "Technology_Description": "\"Intense light beams propagating in nonlinear defocusing media behave identically to fluids. This raises the fascinating perspective of studying fluid dynamics using light. These \"photon fluids\" and have been shown to exhibit remarkable properties such as superfluidity and condensation (similar to Bose-Einstein condensation). Here, we wish to use photon fluids for the creation of artificial flowing spacetime geometries otherwise thought to be the object of more complex and less (experimentally) accessible theories such as event horizons and black holes. The advantage of photon fluids over real fluids in this context is related to the great precision with which the fluid flow is determined by controlling the spatial phase profile of the laser beam. This will allow us for example to also include angular momentum in our black holes, something that has never been done before. In essence, we will study photon fluids with vorticity and look for novel effects including super-radiance amplification at the expense of the rotational motion of the black hole.", "To": ["2017-11-01, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-11-02"], "Project_ID": ["659301"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["THE UNIVERSITY OF LIVERPOOL"], "EU_Contribution": ["EUR 183 454,80"], "Project_Title": ["Exploring glycosidic neo-epitopes of degenerative hippocampal granules in aged mice and humans: implications for ageing and dementia"], "Total_Cost": ["EUR 183 454,80"], "Country": ["United Kingdom"], "Project_ACR": ["GLYCONEOBRAIN"], "Technology_Description": "Ageing is the main correlate of dementia and several other neurodegenerative diseases which currently affect more than 6 million people in Europe. Molecular understanding of these brain conditions is important for their prevention and treatment. In mice, pathological granular structures positive for periodic acid-Schiff stain have been found in the hippocampus with increasing age. The degenerative process of granule formation appears to originate in astrocytes, but adjacent neuronal structures are affected and, accordingly, associated memory impairments have been described. Recent studies reported that granules express glycosidic neo-epitopes, a hallmark of the degenerative granule formation process. This neo-epitope has additionally been found in Lafora bodies of a mouse model of Lafora disease, a fatal neurodegenerative condition. On the other hand, mice serum contains natural IgM antibodies that recognise the glycosidic neo-epitope, suggesting a potentional removal mechanism. In this project, I aim to describe the structure of the glycosidic neo-epitopes of the hippocampal granules as well as the composition of the degenerative granules and Lafora bodies. To achieve these goals, I will employ a multidisciplinary approach exploiting glycomics and neurobiology, with the application of leading-edge technologies that include histological methods, analytical techniques, MALDI-MS imaging and laser-capture microdissection. Moreover, the binding patterns of the anti-neo-epitope natural IgMs will also be explored. Finally and importantly, the expression of the glycosidic neo-epitope in human brain will be assessed. Overall, the knowledge generated will provide new data on brain degenerative processes underlying age-related memory impairments in humans. Ultimately this project will generate new insights for the use of glycosidic neoepitopes as biomarkers for ageing and neurodegenerative diseases, and for prevention and therapeutic strategies using natural antibodies.", "To": ["2019-08-31, ongoing project"], "Meta": [""], "Topic_s": ["MSCA-IF-2015-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2017-09-01"], "Project_ID": ["708563"], "Call_for_Proposal": ["H2020-MSCA-IF-2015"]}, -{"Partners": ["UNIVERZITA KARLOVA"], "EU_Contribution": ["EUR 142 720,80"], "Project_Title": ["Ecological Modelling of the Greenland Ice Sheet Surface Ecosystem"], "Total_Cost": ["EUR 142 720,80"], "Country": ["Czech Republic"], "Project_ACR": ["EMoGrIS"], "Technology_Description": "Glaciers and ice sheets contain distinct ecosystems and are very vulnerable to the ongoing climate change, with potentially significant impacts. However, predictions of future glacier ecosystem change are virtually impossible due to the lack of a theoretical framework of glacier and ice sheet ecosystems that would enable their mathematical modelling. The principal aims of the proposed fellowship are to provide a theoretical framework of the microbe-dominated supraglacial (glacier surface) ecosystem of the Greenland Ice Sheet and to develop a tool for prediction of the future change of the ecosystem, and to establish the Greenland Ice Sheet as a model ecosystem for studying microbial biogeography and diversity patterns. This will be achieved through developing a conceptual model of the system, its mathematical formulation, verification and validation, and subsequent simulations of future climatic scenarios. Furthermore, a sampling strategy will be developed allowing direct testing of relevant ecological hypotheses such as the diversity-productivity relationship. A two-way knowledge transfer is a key feature of this project: The Fellow will take advantage of the expertise of the Supervisor and the Department in ecological theory and modelling, while transferring his knowledge of glaciers as microbe-dominated ecosystems to the Department.", "To": ["2017-12-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Czech Republic"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2016-01-01"], "Project_ID": ["657533"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]}, -{"Partners": ["FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA", "FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA"], "EU_Contribution": ["EUR 1 996 250"], "Project_Title": ["Multipoint Optical DEvices for Minimally invasive neural circuits interface"], "Total_Cost": ["EUR 1 996 250"], "Country": ["Italy", "Italy"], "Project_ACR": ["MODEM"], "Technology_Description": "A primary goal of experimental neuroscience is to dissect the neural microcircuitry underlying brain function, ultimately to link specific neural circuits to behavior. There is widespread agreement that innovative new research tools are required to better understand the incredible structural and functional complexity of the brain. To this aim, optical techniques based on genetically encoded neural activity indicators and actuators have represented a revolution for experimental neuroscience, allowing genetic targeting of specific classes of neurons and brain circuits. However, for optical approaches to reach their full potential, we need new generations of devices better able to interface with the extreme complexity and diversity of brain topology and connectivity.", "To": ["2021-09-30, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Italy"], "Activity": ["Research Organisations", "Chiara Andreoli", "Tel.: +3901071781854", "Fax: +39 010 7170817", "Research Organisations", "Chiara Andreoli", "Tel.: +3901071781854", "Fax: +39 010 7170817"], "From": ["2016-10-01"], "Project_ID": ["677683"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["UNIVERZITA KARLOVA", "UNIVERZITA KARLOVA"], "EU_Contribution": ["EUR 1 362 537,50"], "Project_Title": ["Layered functional materials - beyond 'graphene'"], "Total_Cost": ["EUR 1 362 537,50"], "Country": ["Czech Republic", "Czech Republic"], "Project_ACR": ["BEGMAT"], "Technology_Description": "There is an apparent lack of non-metallic 2D-matrials for the construction of electronic devices, as only five materials of the \u201cgraphene family\u201d are known: graphene, hBN, BCN, fluorographene, and graphene oxide \u2013 none of them with a narrow bandgap close to commercially used silicon. This ERC-StG proposal, BEGMAT, outlines a strategy for design, synthesis, and application of layered, functional materials that will go beyond this exclusive club. These materials \u201cbeyond graphene\u201d (BEG) will have to meet \u2013 like graphene \u2013 the following criteria: ", "To": ["2021-07-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-StG-2015 - ERC Starting Grant"], "Funding_scheme": ["ERC-STG - Starting Grant"], "Coordinated_in": ["Czech Republic"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-08-01"], "Project_ID": ["678462"], "Call_for_Proposal": ["ERC-2015-STG"]}, -{"Partners": ["GOLDSMITHS' COLLEGE", "GOLDSMITHS' COLLEGE"], "EU_Contribution": ["EUR 1 996 830"], "Project_Title": ["Forensic Architecture: The Media Environments of Conflict"], "Total_Cost": ["EUR 1 996 830"], "Country": ["United Kingdom", "United Kingdom"], "Project_ACR": ["FAMEC"], "Technology_Description": "Forensic Architecture is an emergent field that refers to the presentation of architectural evidence in legal contexts. As contemporary conflicts increasingly take place within urban areas, homes and neighbourhoods become targets and a growing number of civilian casualties occur within cities and buildings. Architectural investigation thus becomes an essential tool of conflict analysis, not only for its crucial role in the pursuit of accountability, but also because it enables ground breaking methodological and theoretical inquiries into the context and conduct of urban conflicts. Forensic Architecture (FA), as developed by the PI, employs a novel set of research techniques to analyse violations of international humanitarian law (IHL) and human rights (HR) as they bear upon the built environment. FA employs architecture in three distinct ways: as an object of analysis; as a method of research; and as a mode of presentation. As such FA is able to provide unique, solid, and clear evidence about incidents that other methods of investigation cannot engage with. This proposal, Forensic Architecture: The Media Environments of Conflict (FAMEC) will further develop the field of FA in response to a set of newly evolved challenges. These are concerned with the way in which new modes of documentation and analysis \u2013 based on social and environmental media \u2013 have shifted the relation between conflict and built spaces. Working closely with leading HR organizations, the project will provide novel types of architectural evidence in the context of a number of high profile IHL and HR investigations, in such places as Syria, Israel/Palestine and Amazonia/Brazil. Our forensic work will be the starting point for a set of theoretical reflections \u2013 articulated in books, articles, journal special issues, conferences and exhibitions \u2013 that will ground FA in the histories of forensics, architecture, and human rights.", "To": ["2021-10-31, ongoing project"], "Meta": [""], "Topic_s": ["ERC-CoG-2015 - ERC Consolidator Grant"], "Funding_scheme": ["ERC-COG - Consolidator Grant"], "Coordinated_in": ["United Kingdom"], "Activity": ["Higher or Secondary Education Establishments", "Higher or Secondary Education Establishments"], "From": ["2016-11-01"], "Project_ID": ["682313"], "Call_for_Proposal": ["ERC-2015-CoG"]}, -{"Partners": ["UNIVERSITA DEGLI STUDI DI FERRARA"], "EU_Contribution": ["EUR 168 277,20"], "Project_Title": ["Neotithic transition in the Iberian Peninsula: reviewing an old question from new technological and computational genome wide approaches"], "Total_Cost": ["EUR 168 277,20"], "Country": ["Italy"], "Project_ACR": ["NeoGenHeritage"], "Technology_Description": "The research goal of this proposal revolves around a widely debated topic in archaeology, anthropology and population genetics: the dynamics of the spread of farming into Europe, or Neolithic transition. For a long time, this key event that was to define modern Europeans has fuelled a dichotomic research debate. In short, did the Neolithic spread into Europe as the result of cultural or demographic diffusion? While many approaches can be attempted, in the last few years, ancient DNA (aDNA) studies have strongly contributed to shedding light on this topic, through the recovery and analysis of an increasing number of mitochondrial and nuclear genomes from prehistorical human samples. Far from closing the debate, these palaeogenomes are revealing a more complicated scenario, where the times, paths and genetic legacy of the Neolithic diffusion seem to have been different in different geographic areas. Furthermore, as the genomic data increase, the aDNA field is soon facing the challenge of evolving from a research area largely based on technical development for the recovery of short DNA fragments, to the analysis of larger datasets (ultimately, whole genome data) in the context of human population genetics.", "To": ["2017-08-31, closed project"], "Meta": [""], "Topic_s": ["MSCA-IF-2014-EF - Marie Sk\u0142odowska-Curie Individual Fellowships (IF-EF)"], "Funding_scheme": ["MSCA-IF-EF-ST - Standard EF"], "Coordinated_in": ["Italy"], "Activity": ["Higher or Secondary Education Establishments"], "From": ["2015-09-01"], "Project_ID": ["655478"], "Call_for_Proposal": ["H2020-MSCA-IF-2014"]} -] \ No newline at end of file diff --git a/spiders/H2020_Excellent_Science.xml b/spiders/H2020_Excellent_Science.xml deleted file mode 100644 index a9104a1..0000000 --- a/spiders/H2020_Excellent_Science.xml +++ /dev/null @@ -1,300876 +0,0 @@ - - - - - UNIVERSITA TA MALTA - UNIVERSITY OF LEICESTER - NOVA ID FCT - ASSOCIACAO PARA A INOVACAO E DESENVOLVIMENTO DA FCT - UNIVERSITY OF KENT - AALBORG UNIVERSITET - UNIVERSITY OF GLASGOW - IT-UNIVERSITETET I KOBENHAVN - ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA - UNIVERSITA DEGLI STUDI DI TORINO - ACTYX AG - BITLAND SRL - IXARIS SYSTEMS (MALTA) LIMITED - GREEN BY WEB LDA - COMUNE DI TORINO - XIBIS LIMITED - EXFORMATICS AS - MAIDSAFE.NET LIMITED - CARNEGIE MELLON UNIVERSITY - UNIVERSIDAD DE BUENOS AIRES - THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS - MCAFEE ARGENTINA S.A. - - - EUR 630 000 - - - Behavioural Application Program Interfaces - - - EUR 742 500 - - - Malta - United Kingdom - Portugal - United Kingdom - Denmark - United Kingdom - Denmark - Italy - Italy - Germany - Italy - Malta - Portugal - Italy - United Kingdom - Denmark - United Kingdom - United States - Argentina - United States - Argentina - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - APIs are typically flat structures, i.e. sets of service/method signatures specifying the expected service parameters and the kind of results one should expect in return. However, correct API usage also requires the individual - services to be invoked in a specific order. Despite its importance, the latter information is either often omitted, or stated informally via textual descriptions. Behavioural Types are a suite of technologies that formalise of this information, - elevating flat API descriptions to a graph structure of services. This permits automated analyses for correct API compositions so as to provide guarantees such as service compliance, deadlock freedom, dynamic adaptation in the presence of failure, - load balancing etc. The proposed project aims to bring the existing prototype tools based on these technologies to mainstream programming languages and development frameworks used in industry. - - 2022-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Malta - - - BEHAPI - - - H2020-MSCA-RISE-2017 - - - 778233 - - - - - UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA - THE UNIVERSITY OF BIRMINGHAM - UNIVERSITE DE MONS - UNIVERSITA DEGLI STUDI DI GENOVA - MASD INGENIERIA DE VALORIZACION DE RESIDUOS DE ORIGEN AGROFORESTAL - STELLENBOSCH UNIVERSITY - INSTITUTE OF CHEMISTRY, CHINESE ACADEMY OF SCIENCES - THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND - NATIONAL UNIVERSITY CORPORATION YAMAGATA UNIVERSITY - UNIVERSIDAD SIMON BOLIVAR - - - EUR 1 260 000 - - - SYNTHESIS, CHARACTERIZATION, STRUCTURE AND PROPERTIES OF NOVEL BIODEGRADABLE POLYESTERS - - - EUR 1 395 000 - - - Spain - United Kingdom - Belgium - Italy - Spain - South Africa - China - United States - Japan - Venezuela - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - BIODEST (Synthesis, Characterization, Structure and Properties of Novel Biodegradable Polyesters) Research and Innovation Staff Exchange (RISE) project aims to strengthen around student and staff exchanges with the aim to - improve skills and knowledge of the participating partners and promote collaboration between four European Research organizations: University of the Basque Country (Spain), University of Mons (Belgium), University of Genova (Italy), and University of - Warwick (U.K.) and five non-EU Research Organizations: University of Tulane (USA), Chinese Academy of Science (China), Simon Bolivar University (Venezuela), University of Stellenbosch (South Africa), and Yamagata University (Japan). Moreover the - non-academic European organization “Ma+D - Waste Valorization Engineering” will collaborate in the networking activities. The project will provide support for the participating research organizations to establish or reinforce long-term research - cooperation in the topic of novel biodegradable polyesters through a coordinated joint programme of exchange of researchers for short periods. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Spain - - - BIODEST - - - H2020-MSCA-RISE-2017 - - - 778092 - - - - - ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA - ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA - - - EUR 149 937,50 - - - Luminescent silicon nanocrystals as bioimaging systems - - - EUR 149 937,50 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Optical imaging is a powerful tool for light-guided surgery and for the study of biological functions via dynamic visualization of processes in tissues and cells. Most of optical imaging techniques utilise fluorescent probes - that can suffer from low contrast, due to scattering of the excitation light, and low tissue penetration. Silicon nanocrystals (SiNCs), developed within the ERC PhotoSi project, are a very promising alternative for this purpose: silicon is - essentially non-toxic, easily available, and it can be covalently linked with dyes. The result is a highly-robust and biocompatible hybrid material, which exhibits colour tunability across the visible and near-infrared region. On top of that, the - extraordinary brightness of the material coupled to a long-lived luminescence (lifetime of the hundreds of microseconds) enables time-gated detection. Therefore, SiNBioSys technology greatly improves the contrast of the obtained images with a - low-cost equipment and with a material based on abundant and biocompatible elements (Si, C, O, H). An international patent application on the key underlying technology was filed in 2015 and subsequently nationalized in the primary markets (Europe and - USA). Based on these premises, this proposal is intended to gather sufficient technical and commercial evidence to make the SiNBioSys technology attractive for further investment in the development of a new commercial product by: (i) optimization and - validation of SiNCs against current gold standards; (ii) an in-depth market analysis; (iii) a realistic business development strategy with demonstrations to leading companies in the field. The proposed technology will thus bring an economic impact, - as well as social benefits: it will demonstrate its ability to replace currently used expensive setups and will enable innovative imaging tools for early diagnosis of diseases, particularly in the field of cancer and neuroscience. - - 2019-04-30, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Italy - - - SiNBioSys - - - ERC-2017-PoC - - - 780061 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 150 000 - - - OCEAN SENTINEL - - - EUR 150 000 - - - France - France - - - Research Organisations - Research Organisations - - Fisheries are operating worldwide over nation’s Economic Exclusive Zones (EEZ) as well as over international waters. Information on the location of fishing is rarely known, especially in international waters, yet it is - critical since in many oceanic sectors non declared and illegal fisheries are affecting negatively ecosystems through over exploitation and by catch of non-target species Knowledge about the distribution of fishing boats is fundamental for the - regulation of fishing activities as well for the conservation of the oceans. I propose a New Concept of ocean surveillance based on new bio-logging technologies fitted on large foraging marine predators. The OCEAN SENTINEL Proof of this Concepts will - (1) develop a logger called CENTURION that couple a XGPS platform detecting and locating radar emissions, with a satellite transmission system (Argos) that would send instantaneously the location of vessels to a receiving site, (2) deploy the logger - on wide ranging animals used as platforms and (3) make available immediately the information obtained from the CENTURION logger through a website. The OCEAN SENTINEL programme will generate important social benefits by providing information to a wide - range of beneficiaries, from governments or regional authorities managing EEZ and natural resources, regional or national fishing authorities, researchers and non-governmental organisation in conservation. The concept will be tested in the Southern - Indian Ocean from Crozet and Kerguelen Islands where valuable and extensive fisheries operate in EEZs and over oceanic waters. This concept has the potential to be used in other areas where information on fisheries location is needed. The project - will also lead to further discoveries on the relationship between seabirds and fisheries as well on the extent of fisheries in zones where surveillance by conventional methods is not possible. - - 2019-06-30, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - France - - - OCEAN SENTINEL - - - ERC-2017-PoC - - - 780058 - - - - - UNIVERSIDADE DE AVEIRO - VRIJE UNIVERSITEIT BRUSSEL - TECHNISCHE UNIVERSITAET DRESDEN - KAUNO TECHNOLOGIJOS UNIVERSITETAS - INSTITUTE OF MAGNETISM OF THE NATIONAL ACADEMY OF SCIENCE OF UKRAINE AND THE MINISTRY OF EDUCATION AND SCIENCE OF UKRAINE - WMT WIRE MACHINE TECHNOLOGIES LTD - SSPA SCIENTIFIC AND PRACTICAL MATERIALS RESEARCH CENTRE OF NAS OF BELARUS - - - EUR 558 000 - - - Physical principles of the creation of novel SPINtronic materials on the base of MULTIlayered metal-oxide FILMs for magnetic sensors and MRAM - - - EUR 558 000 - - - Portugal - Belgium - Germany - Lithuania - Ukraine - Israel - Belarus - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - - The main goal of the project is the elaboration of research and development principles and technology, as well as creation of novel nanoheterostructures for application in spintronic devices, first of all, in magnetic field - sensors and magnetoresistive random access memories. The key research and technological aspects are focused on the formation of layers and/or nanosized grains of a ferromagnetic material with an ultimate degree of conduction electron spin - polarization, separated by dielectric interlayers. The main research, technological and innovation aspects of the work are aimed at an increase of the devices’ sensitivity to magnetic fields thanks to the high degree of spin polarization and to the - magnetoresistance due to electron quantum tunneling through dielectric barriers. - - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Portugal - - - SPINMULTIFILM - - - H2020-MSCA-RISE-2017 - - - 778308 - - - - - NOVA ID FCT - ASSOCIACAO PARA A INOVACAO E DESENVOLVIMENTO DA FCT - DANMARKS TEKNISKE UNIVERSITET - UNIVERSIDAD DE MALAGA - ECO RECYCLING SOCIETA A RESPONSABILITA LIMITATA - AMPHOS 21 CONSULTING SL - E-MINES - LOMARTOV SL - NORTHEASTERN UNIVERSITY - LEHIGH UNIVERSITY CORPORATION - - - EUR 693 000 - - - Thinking rough towards sustainability - - - EUR 733 500 - - - Portugal - Denmark - Spain - Italy - Spain - France - Spain - United States - United States - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - To tackle its critical raw material (CRM) dependency, Europe needs comprehensive strategies based on sustainable primary mining, recovery from secondary resources and recycling. The EC classified 20 CRMs due to their high - economic importance and high risk of supply interruption. e.THROUGH has the ambitious vision of turning the challenge of CRMs dependence into a strategic strength for Europe, contributing towards declassifying some CRMs, as tungsten, indium, gallium - and chromium, by: 1) Promoting new trends in the characterization and exploration of mineral deposits; 2) Mapping CRMs between EU mining regions; 3) Gaining knowledge on innovative processes for recovery secondary CRMs; 4) Redesign construction - materials using secondary materials, closing loops, strongly supporting waste minimization; 5) Life Cycle Assessment (LCA) for the evaluation of global environmental impacts; 6) Transferring newly generated knowledge to stakeholders, both for policy - development and standardization, and for shaping responsible behaviours. e.THROUGH is an intersectoral and interdisciplinary consortium of EU & Third Country partners of leading institutions that see waste as a resource to recover CRMs, - influencing the whole value chain. By training human resources in CRMs´value chain, their recovery, recycling, further reuse and LCA, they become the much needed young and senior scientists and engineers for the growing EU CRM industry. The - consortium comprises 40% industry and 60% research partners. This should help push Europe to the forefront in CRM sectors, providing eco-friendly alternatives in supply. The generated scientific relevant knowledge will be transferred to shape - industries, communities and individual citizens’ behaviour, fostering corporate sustainability performance, important to influence economic agents’ choices. e.THROUGH will generate a win-win situation for both the environment and the economy, - promoting the required transition towards a sustainable society. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Portugal - - - e.THROUGH - - - H2020-MSCA-RISE-2017 - - - 778045 - - - - - UNIVERSITE DE PICARDIE JULES VERNE - INSTITUT JOZEF STEFAN - NANOTECHCENTER LLC - UNIVERSITE CADI AYYAD - SOUTHERN FEDERAL UNIVERSITY - - - EUR 837 000 - - - Engineering of Nanostructures with Giant Magneto-Piezoelectric and Multicaloric Functionalities - - - EUR 936 000 - - - France - Slovenia - Ukraine - Morocco - Russia - - - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Nowadays smart materials play a crucial role in the next-generation of intelligent devices and sensors, smart homes, autonomous devices, and robotics. Nanostructuring materials open up new horizons bringing in their - multifunctionality and reduce the energy consumption. This reveals new scientific avenues and paves ways for breakthroughs in technology. Realization of structured materials with the strong coupling of electric and magnetic order and large - multicaloric properties is a milestone for modern electronics and the gate for fascinating applications. In this context, we develop the partnership within the RISE consortium ENGIMA, involving the academic partners from two EU Member States, France - and Slovenia Third Countries Universities in Morocco and Russia the non-academic SME from Associated Country, Ukraine. The network combines the complementary interdisciplinary and intersectoral expertise with established collaboration between - partners and clear potential for skills transfer and exchange of knowledge, extended from fundamental to applied physics and from material chemistry to industrial nanotechnologies. Consortium defined a research objective of exploring the - nanostructures in a form of tethered magnetic 1-D/piezoelectric nanostructures and magnetic/piezoelectric superlattices to obtain new ferroic materials with giant magnetoelectric and multicaloric functionalities that have potential applications as - magnetoelectric sensors and, telecommunication devices. This task will be achieved by joining the efforts through the staff exchange, sharing knowledge, innovation and by multidisciplinary training of the team of collaborating young researchers able - to conduct the research and exploit its application to this new area. - - 2021-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - France - - - ENGIMA - - - H2020-MSCA-RISE-2017 - - - 778072 - - - - - UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN - CONCERN WORLDWIDE LBG - RESEAU POUR L'ACTION HUMANITAIRE (NETWORK ON HUMANITARIAN ACTION) - FUTURE ANALYTICS CONSULTING LIMITED - WOLAITA SODO UNIVERSITY - - - EUR 2 097 000 - - - Building Resilience through Education - - - EUR 2 097 000 - - - Ireland - Ireland - Belgium - Ireland - Ethiopia - - - Higher or Secondary Education Establishments - Other - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - The Building Resilience Through Education (BRTE) Consortium brings together partners from academia, the private sector and the NGO sector to find innovative ways to strengthen the resilience of communities affected by - recurring disasters. This project has its origins in an ex-post impact evaluation of Concern Worldwide’s twenty-five year engagement in Wolaita, Ethiopia. Conducted by University College Dublin’s Centre for Humanitarian Action in collaboration with - Wolaita Sodo University, the evaluation found that, despite significant improvements in communities’ capacities to both absorb the effects of recurring disasters and to adapt their livelihoods based on experience of recent disasters, they remain - extremely vulnerable to their natural and environmental context. As a result there is an urgent need for a novel approach that moves beyond supporting the mere absorption of or adaptation to recurring shocks and that transforms the capacity of - exposed communities. The BRTE partnership has identified the importance of education in bringing about this transformative change. It aim is to build the capacity of Wolaita’s educational institution in pursuit of the following objectives: - - 2021-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Ireland - - - BRTE - - - H2020-MSCA-RISE-2017 - - - 778196 - - - - - UPPSALA UNIVERSITET - SITEX 45 SRL - INSTITUT PASTEUR DE TUNIS - UNIVERSIDAD COMPLUTENSE DE MADRID - UNIVERSITATEA SPIRU HARET - ELVESYS SAS - UNITED STATES DEPARTMENT OF AGRICULTURE - UNIVERSIDAD DE PAMPLONA - - - EUR 1 395 000 - - - Volatolomics test for the diagnosis of bovine tuberculosis - - - EUR 1 404 000 - - - Sweden - Romania - Tunisia - Spain - Romania - France - United States - Colombia - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - - Bovine tuberculosis, caused by Mycobacterium bovis and other members of the M. tuberculosis complex, is a serious global disease with significant impact on animal health, public health, and international trade. This study will - focus on investigating the feasibility of a non-invasive methodology for the diagnosis of bovine tuberculosis in cattle. Our approach will be based on the detection via volatile organic compounds of the disease fingerprint in several non-invasive - samples, employing analytical methods and chemical sensing devices. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Sweden - - - bTB-Test - - - H2020-MSCA-RISE-2017 - - - 777832 - - - - - UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN - MATER MISERICORDIAE UNIVERSITY HOSPITAL LIMITED - UNIVERSITY OF ULSTER - UNIVERSITA DEGLI STUDI DI PADOVA - G.TEC MEDICAL ENGINEERING GMBH - CONGREGAZIONE DELLE SUORE INFERMIERE DELL ADDOLORATA - EKSO BIONICS INC - - - EUR 144 000 - - - Physiological and Rehabilitation Outcomes: Gains from Automated Interventions in stroke Therapy (PRO GAIT) - - - EUR 157 500 - - - Ireland - Ireland - United Kingdom - Italy - Austria - Italy - United States - - - Higher or Secondary Education Establishments - Other - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Developments in robotics allow people with profound neuromuscular deficits after stroke to walk with assistance (during the gait cycle) using an exoskeleton robot. Integrating a robotic device with individualised user - electroencephalography (EEG /electrical activity in the motor areas in the brain) and EMG (muscle)feedback would allow more physiological and targeted gait parameters in response to effort, and confer neuroplastic training effects including - neuromodulation of temporal and spatial features of gait. - - 2022-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Ireland - - - PRO GAIT - - - H2020-MSCA-RISE-2017 - - - 778043 - - - - - UNIWERSYTET WARSZAWSKI - UNIWERSYTET IM. ADAMA MICKIEWICZA W POZNANIU - RIJKSUNIVERSITEIT GRONINGEN - STICHTING FRYSKE AKADEMY - UNIVERSITEIT LEIDEN - STOWARZYSZENIE NA RZECZ ZACHOWANIA DZIEDZICTWA KULTUROWEGO MIASTA WILAMOWICE WILAMOWIANIE - GRUPPO DI AZIONE LOCALE LO SVILUPPORURALE DELL'AREA GRECANICA SCARL - LATGOLYS STUDENTU CENTRS - THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL - THE UNIVERSITY OF TEXAS SYSTEM - YALE UNIVERSITY - ARENET - INSTITUTO DE DOCENCIA E INVESTIGACION ETNOLOGICA DE ZACATECAS AC - SMITHSONIAN INSTITUTION - - - EUR 1 579 500 - - - Minority Languages, Major Opportunities.Collaborative Research, Community Engagement and Innovative Educational Tools - - - EUR 1 687 500 - - - Poland - Poland - Netherlands - Netherlands - Netherlands - Poland - Italy - Latvia - United States - United States - United States - Mexico - Mexico - United States - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Other - - The linguistic and cultural diversity of Europe is crucial to the capacity for problem solving and creative thinking upon which our general wellbeing and economic prosperity depend in an increasingly global and technological - society. However, language diversity and immigration are often seen as threats and are challenged by discriminatory attitudes and state policies. COLING will provide justification for the strengthening and revitalization of minority languages, as - well as guidelines to implement concrete programs for this purpose. The project’s objectives focus on developing and sharing expert knowledge on language revitalization programs that combine community-driven and top-down approaches; promoting engaged - collaboration among academic, nonprofit and community-based institutions; developing efficient teaching methodologies, teacher training, and curricula for minority languages; establishing a new international academic program in minority studies at - the partner institutions, in which the new methodologies and curricula will be employed. To this end, COLING affiliated researchers will work together to a) document and archive linguistic-cultural diversity and language practices of indigenous - communities and migrants; b) explore the Trans-Atlantic perspectives and historical ties between the Americas and Europe that demonstrate the cultural resilience of indigenous peoples and the evolution of heritage cultures in mixed societies; c) - develop innovative teaching methodologies through content modules in textual and digital formats and d) investigate the causative and correlative relationships between language identities, linguistic and cultural discrimination, self-confidence, - trauma and well-being, and social cohesion in multilingual and multicultural contexts. COLING will organize summer schools, workshops, trainings to bring together researchers, practitioners and community members, permitting the exchange of skills, - best practices and research results. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Poland - - - COLING - - - H2020-MSCA-RISE-2017 - - - 778384 - - - - - CIIMAR - Centro Interdisciplinar de Investigação Marinha e Ambiental - UNIVERSIDAD DE SANTIAGO DE COMPOSTELA - Q TECHNOLOGIES LTD - UNIVERSITA DEGLI STUDI DI TRIESTE - THE QUEEN'S UNIVERSITY OF BELFAST - MARINE BIOLOGICAL ASSOCIATION OF THE UNITED KINGDOM - INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER - AGUAS DE GAIA EM SA - Institut National des Sciences et Technologies de la Mer - APPLIED GENOMICS LTD - E&H SERVICES AS - NATURAL BIOTEC SL - UNIVERSIDADE DE CABO VERDE - UNIVERSITE CHOUAIB DOUKKALI - - - EUR 702 000 - - - Emergent Marine Toxins in the North Atlantic and Mediterranean: New Approaches to Assesstheir Occurrence and Future Scenarios in the Framework of Global Environmental Changes. - - - EUR 702 000 - - - Portugal - Spain - United Kingdom - Italy - United Kingdom - United Kingdom - France - Portugal - Tunisia - United Kingdom - Czech Republic - Spain - Cape Verde - Morocco - - - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - EMERTOX aims at mapping the actual situation in emergent marine toxins and the producing organisms, developing new approaches to assess their occurrence and predicting the possible future scenarios in the framework of global - warming. The partnership, formed by a multidisciplinary team, will produce a joint research and innovation project that will exploit the complementary expertise of the participants and will create synergies among them. The main objectives are: - - 2022-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Portugal - - - EMERTOX - - - H2020-MSCA-RISE-2017 - - - 778069 - - - - - INSTYTUT NISKICH TEMPERATUR I BADAN STRUKTURALNYCH IM. WLODZIMIERZA TRZEBIATOWSKIEGO POLSKIEJ AKADEMII NAUK - VILNIAUS UNIVERSITETAS - UNIVERSIDADE DE AVEIRO - HELMHOLTZ-ZENTRUM GEESTHACHT ZENTRUM FUR MATERIAL- UND KUSTENFORSCHUNG GMBH - INSTITUTE OF PHYSICS OF NATIONAL ACADEMY OF SCIENCE OF UKRAINE - NANOCERAMICS SPOLKA AKCYJNA - FRANCISK SKORINA GOMEL STATE UNIVERSITY - SSPA SCIENTIFIC AND PRACTICAL MATERIALS RESEARCH CENTRE OF NAS OF BELARUS - - - EUR 783 000 - - - Transition metal oxides with metastable phases: a way towards superior ferroic properties - - - EUR 783 000 - - - Poland - Lithuania - Portugal - Germany - Ukraine - Poland - Belarus - Belarus - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - - The main objective of the project is development of complex transition metal oxides with perovskite-like structure having improved and controllable (multi)ferroic properties. The mentioned materials are manganites and ferrites - with optimal composition having distinct magnetization, polarization, (magneto)transport properties or magnetoelectric coupling. The idea of the project is to utilize reduced structural stability of these oxides which increases their sensitivity to - external stimuli. Improved functional properties of these oxides can be controlled via modification of the chemical bond character, structural parameters, stoichiometry, defects etc. The reduced stability is associated with the metastable structural - state formed in the vicinity of the phase boundaries, while this state presumably consists of coexistent nanoscale regions of the adjacent structural phases. There are two ideas to create metastable state: the first one – to design ceramics via - chemical substitution and post-synthesis treatment by high pressure and/or thermal cycling in gases to induce nanoscale regions, the second one assumes chemical routes synthesis of films and ceramics. Besides the fundamental interest of the phase - transitions and related phenomena affecting properties of the oxides the applicants consider them to be effective materials for electronic applications (as sensors, magnetic memory elements, filters etc.). Research of these oxides requires - consolidative efforts of specialists in different scientific areas - Materials Science, Theoretical Physics, Solid State Physics etc. as well as an access to unique equipment and facilities. Another important objective of the project is a formation - of interdisciplinary network of teams and specialists with different scientific backgrounds which will ensure effective transfer of actual knowledge and skills. Development of the transition metal oxides with controllable properties has promising - commercial opportunities for the involved SME. - - 2021-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Poland - - - TransFerr - - - H2020-MSCA-RISE-2017 - - - 778070 - - - - - UNIVERSITY OF PIRAEUS RESEARCH CENTER - UNIVERSIDAD DE MALAGA - BEIA CONSULT INTERNATIONAL SRL - NEUROSOFT SOFTWARE PRODUCTIONS SA - - - EUR 1 080 000 - - - Scalable, trustEd, and interoperAble pLatform for sEcureD smart GRID - - - EUR 1 080 000 - - - Greece - Spain - Romania - Greece - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The rapid evolution of ICT has revealed the potential for centrally monitoring, controlling, and optimising the power grid. In this context, a more intelligent, responsive, and efficient, system has been devised, known as the - Smart Grid (SG). As explained in the EU Third Energy Package the SG will support a dynamic two-way information exchange between utility companies and their customers, contributing towards a smart and sustainable energy management in Europe and the - establishment of a wiser energy consumption mentality. However, besides the benefits of such an endeavour, the power grid will be exposed to security threats inherited from the ICT sector, while privacy issues and new vulnerabilities, related to the - specific characteristics of the SG infrastructure, will emerge. The problem is assessed as crucial, if we consider that a potential attack to the SG may lead to cascading failures, ranging from destruction of other interconnected critical - infrastructures to loss of human lives. Thus, the development of a security platform tailored to the SG is required, that i) can efficiently manage the plethora of SG nodes, ii) deal with potential malicious hardware or software modifications due to - the physical access of the customers to the SG nodes, and iii) operate over heterogeneous systems. Considering all the above, SealedGRID aims at bringing together experts from industry and academia from cross-sectorial research areas having - complementary background with the long-term goal to design, analyse, and implement a scalable, highly trusted and interoperable SG security platform. The platform will combine, for the very first time, technologies like Blockchain, Distributed Hash - Tables, Trusted Execution Environments, and OpenID Connect, while for its realization the SealedGRID consortium is committed to a fully-integrated and multi-disciplinary secondment programme combined with a set of networking, dissemination, and - exploitation activities. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Greece - - - SealedGRID - - - H2020-MSCA-RISE-2017 - - - 777996 - - - - - UNIVERSIDADE DE EVORA - UNIVERSIDADE NOVA DE LISBOA - INSTITUTO DE CIENCIAS SOCIAIS - INSTITUTO UNIVERSITARIO DE LISBOA - UNIVERSIDAD DE CANTABRIA - UNIVERSIDAD DE SANTIAGO DE COMPOSTELA - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE - BROWN UNIVERSITY - UNIVERSIDADE DE CABO VERDE - UNIVERSIDADE FEDERAL DA BAHIA - UNIVERSIDAD NACIONAL DE LA PLATA - EL COLEGIO DE MICHOACAN - - - EUR 1 030 500 - - - Rebellion and Resistance in the Iberian Empires, 16th-19th centuries - - - EUR 1 030 500 - - - Portugal - Portugal - Portugal - Portugal - Spain - Spain - Germany - Chile - United States - Cape Verde - Brazil - Argentina - Mexico - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - Economic inequalities, social exclusion, discrimination against minorities, cultural resistance and disruption of social cohesion – these are all key concerns in the current European and global agenda, both in scholarly work - and policy-making. RESISTANCE aims at analysing these issues by focusing on the processes of resistance carried out by social actors that have been historically disadvantaged, discriminated against and dominated. By using a concept of resistance that - connects continued and less visible forms of resistance, cultural dissent and violent revolts, the ultimate goal of RESISTANCE is to produce a reinterpretation of the universe of “the dominated”. RESISTANCE will provide an understanding of how these - actors could influence processes of social change, either by opening up societies to diversity and making them more inclusive and equal, or, conversely, by causing the increase of repression. - - 2022-05-31, Grant Agreement signed - - - 2018-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Portugal - - - RESISTANCE - - - H2020-MSCA-RISE-2017 - - - 778076 - - - - - ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA - FONDAZIONE RECUPERO E VALORIZZAZIONE DELLA MEMORIA STORICA DEL CAMPO DI FOSSOLI - UNIVERSITEIT VAN AMSTERDAM - STICHTING CASTRUM PEREGRINI - UNIVERSIDAD NACIONAL DE COLOMBIA - UNIVERSIDAD DE BUENOS AIRES - MUSEO DE SITIO ESMA - EX CENTRO CLANDESTINO DE DETENCIÓN, TORTURA Y EXTERMINIO - - - EUR 553 500 - - - Questioning Traumatic Heritage: Spaces of Memory in Europe, Argentina, Colombia - - - EUR 553 500 - - - Italy - Italy - Netherlands - Netherlands - Colombia - Argentina - Argentina - - - Higher or Secondary Education Establishments - Other - Higher or Secondary Education Establishments - Other - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - SPEME will develop a joint program of exchanges between academic researchers - working on memory, trauma and heritage - and non-academic professionals - working in the fields of memory museums and sites of memory - between - Italy, The Netherlands, Argentina and Colombia. - - - 2022-06-30, Grant Agreement signed - - - 2018-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Italy - - - SPEME - - - H2020-MSCA-RISE-2017 - - - 778044 - - - - - LATVIJAS UNIVERSITATE - SUMY STATE UNIVERSITY - THE UNIVERSITY OF SHEFFIELD - UNIVERSITA DEGLI STUDI DI MODENA E REGGIO EMILIA - OSTEOPLANT RESEARCH AND DEVELOPMENT SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA - NANOPHARMA AS - EESTI MATERJALITEHNOLOOGIATE ARENDUSKESKUSE AS - - - EUR 1 008 000 - - - Nanostructural surface development for dental implant manufacturing - - - EUR 1 008 000 - - - Latvia - Ukraine - United Kingdom - Italy - Poland - Czech Republic - Estonia - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The project NanoSurf is targeted to strengthen international and intersectoral collaboration in dental implant research, sharing new ideas and knowledge transfer from research to market and vice versa. We will investigate - nanostructured metal oxide coatings, 3D scaffolds, obtained by electrospinning deposition of organic nanofibers and lazer patterning of the implant surface using biotechnology, cell engineering and nanotechnology. Interdisciplinary project research - and innovation goals are targeted to develop a new class of dental implants with advanced mechanical properties and improved surfaces, treated with nanotechnological methods which will demonstrate high biocompatibility, antibacterial properties and - integration with a patient’s bone. The developed devices will simplify dental surgery and avoid bacterial inflammatory complications after the implant surgery. This can provide better dental services and improve health of EU society. - - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Latvia - - - NanoSurf - - - H2020-MSCA-RISE-2017 - - - 777926 - - - - - THE UNIVERSITY OF EXETER - THE UNIVERSITY OF EXETER - - - EUR 149 938 - - - Forefront UAV Technology for Underpinning Rainforest Environmental Sustainability - - - EUR 149 938 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The proposed FUTURES project will use the novel UAV-Lidar technology conceived and developed in the current ERC-funded PAST project, in collaboration with the Brazilian National Institute for Space Research, in an entirely - different socio-economic application aimed at helping Extractive Reserves (RESEXs) of the Brazilian Amazon. FUTURES proposes to utilise the UAV-Lidar system for creating 3D maps of forest structure and ground digital terrain models with unprecedented - detail and interpret these data to improve the sustainable relationship between the RESEX forest residents and their environment, while maintaining and strengthening their economy and culture, and providing information to help them address emerging - challenges. More specifically, FUTURES proposes to test the UAV-Lidar system for the following applications tailored to RESEXs: a) develop alternative options for sustainable extraction of non-timber forest products; b) design flood mitigation - strategies, such as route planning for easier access to healthcare and emergency services, schools and local consumer markets during the rainy season; c) identify new, sustainable, under-forest fisheries; and d) increase the awareness of - archaeological heritage in RESEXs with implications to develop cultural heritage tourism. Addressing the above challenges are also important for RESEXs and the Brazilian government in materialising their REDD+ (Reducing Emissions from Deforestation - and forest Degradation) initiative, and for the European Union to ensure its success and leadership in implementing its forest conservation, sustainability and carbon mitigation goal of reducing tropical deforestation to at least 50% by 2020. - - 2019-06-30, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - FUTURES - - - ERC-2017-PoC - - - 777845 - - - - - BOURNEMOUTH UNIVERSITY - UNIVERSITETET I BERGEN - UNIVERSITY OF BRADFORD - UNIVERSIDAD DE CANTABRIA - UNIVERSIDAD DE SEVILLA - UAB INDEFORM - COMSATS INSTITUTE OF INFORMATION TECHNOLOGY - UNIVERSITI TEKNOLOGI MALAYSIA - - - EUR 535 500 - - - PDE-based geometric modelling, image processing, and shape reconstruction - - - EUR 535 500 - - - United Kingdom - Norway - United Kingdom - Spain - Spain - Lithuania - Pakistan - Malaysia - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Geometric modelling, image processing, and shape reconstruction have huge applications in various sectors and greatly impact on EU’s economy, human health, security, entertainment and others. Existing problems such as big data - and heavy manual operations in geometric modelling, incapacity in image processing in continuous domains, and lack of continuity and differentiability in shape reconstruction seriously affect quality, efficiency and capacity. Partial differential - equation (PDE) based techniques provide effective solutions to these problems. Current PDE-based modelling cannot achieve both powerful capacity and high computational performance. PDE-based image processing suffers from expensive cost and local - minimization. PDE-based shape reconstruction has not been developed. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - United Kingdom - - - PDE-GIR - - - H2020-MSCA-RISE-2017 - - - 778035 - - - - - WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER - UNIVERSIDAD POMPEU FABRA - UNIVERSITE DE BORDEAUX - UNIVERSITE DE CAEN NORMANDIE - ECOLE NATIONALE SUPERIEURE D'INGENIEURS DE CAEN - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - UNIVERSITA DEGLI STUDI DI GENOVA - TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY - INSTITUTO SUPERIOR TECNICO - POLITECNICO DI MILANO - THE UNIVERSITY OF NOTTINGHAM - ECOLE POLYTECHNIQUE - UNIVERSITEIT TWENTE - UNIVERSITE LYON 1 CLAUDE BERNARD - ASTRAZENECA UK LIMITED - MEDIGUIDE LTD - CAMELOT BIOMEDICAL SYSTEMS SRL - THE MATHWORKS LIMITED - CLK GMBH - DATEXIM - CLINICAL SCIENCE SYSTEMS - THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - CARNEGIE MELLON UNIVERSITY - - - EUR 1 111 500 - - - Nonlocal Methods for Arbitrary Data Sources - - - EUR 1 111 500 - - - Germany - Spain - France - France - France - United Kingdom - Italy - Israel - Portugal - Italy - United Kingdom - France - Netherlands - France - United Kingdom - Israel - Italy - United Kingdom - Germany - France - Netherlands - United States - United States - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In NoMADS we focus on data processing and analysis techniques which can feature potentially very complex, nonlocal, relationships within the data. In this context, methodologies such as spectral clustering, graph partitioning, - and convolutional neural networks have gained increasing attention in computer science and engineering within the last years, mainly from a combinatorial point of view. However, the use of nonlocal methods is often still restricted to academic pet - projects. There is a large gap between the academic theories for nonlocal methods and their practical application to real-world problems. The reason these methods work so well in practice is far from fully understood. - - 2022-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Germany - - - NoMADS - - - H2020-MSCA-RISE-2017 - - - 777826 - - - - - UNIVERSITY OF NEWCASTLE UPON TYNE - THE HEBREW UNIVERSITY OF JERUSALEM - UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN - UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA - THE UNIVERSITY OF BIRMINGHAM - QUANTUMDX GROUP LIMITED - NATIONAL UNIVERSITY OF SINGAPORE PUBLIC COMPANY LIMITED BY GUARANTEE - KOKURITSU DAIGAKU HOJIN HOKKAIDO DAIGAKU - UNIVERSITY OF MELBOURNE - BRIGHAM YOUNG UNIVERSITY NON PROFIT CORPORATION - UNIVERSITY OF WESTERN SYDNEY - - - EUR 499 500 - - - Molecular diagnostics through DNA modification and interfacial engineering - - - EUR 522 000 - - - United Kingdom - Israel - Ireland - Spain - United Kingdom - United Kingdom - Singapore - Japan - Australia - United States - Australia - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - DNASURF will establish a global network of excellence for exchange of research staff and transfer of knowledge, to provide high-level training and career advancement opportunities, focussed on interdisciplinary DNA technology - with a view to development of innovative solutions for DNA molecular diagnostics. It brings together leading academic and commercial scientific groups from 3 European and 4 non-European countries who will study complementary aspects of DNA synthesis, - DNA nanoarchitectures, DNA at surfaces, and DNA for biomedical devices. DNASURF aims to transform creative scientific ideas into innovative biomedical products and services by exploiting and integrating advances in DNA synthesis, nanotechnology, - interfacial engineering, and microsystems research. The pathway from basic science to commercial applications is facilitated by collaboration between academic labs and SMEs that are at the forefront of new methodologies. The ambitious scientific - objectives of DNASURF are complemented by the aim to increase cutting-edge technical knowledge and professional skills across the network through staff exchanges and training in key methods as well as commercialisation of research. A long term goal - of DNASURF is to consolidate a group of collaborative young multi-disciplinary scientists that can bring about future development of disruptive technologies in the commercially important scientific field of molecular diagnostics. - - 2021-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - United Kingdom - - - DNASURF - - - H2020-MSCA-RISE-2017 - - - 778001 - - - - - UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN - HUNTINGTON'S DISEASE ASSOCIATION OF IRELAND - THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN - UNIVERSITAET ULM - THE UNIVERSITY OF READING - COMTRADE PROGRAMSKE RESITVE DOO - ICON CLINICAL RESEARCH LIMITED - ICON CLINICAL RESEARCH - - - EUR 828 000 - - - Patient Centered Connected Health Model of Care for Huntingtons Disease - - - EUR 828 000 - - - Ireland - Ireland - United Kingdom - Germany - United Kingdom - Slovenia - Ireland - France - - - Higher or Secondary Education Establishments - Other - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - HD is a monogentic disease, meaning modification in a single gene occurring in all cells of the body. In Western countries it is estimated that 5-7 people per 100,000 are affected by HD. Currently there is no cure for the - disease and effective management is key to quality of life for those who are affected. Patients and families who are living with the disease face multiple social and self-management issues. For example, stigma of the disease alongside social - isolation have been key drivers in terms of high levels of mental health difficulties. CH has the ability to assist with many of the difficulties faced by HD, RD and indeed other symptom related diseases. For example, CH can monitor and identify key - intervention points along the disease progression pathway, it can inform and facilitate integrated care, it can assist with joining key stakeholders together in a shared ecosystem, and importantly it can assist patients and their families in terms of - reducing isolation, optimising self-management and thus increasing empowerment and self-actualisation. Further, CH has the ability to optimise scarce resources in an over stretched health care system and thus produce effective and efficient outcomes. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Ireland - - - CareHD - - - H2020-MSCA-RISE-2017 - - - 777991 - - - - - ECOLE NATIONALE DES PONTS ET CHAUSSEES - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - CABLENET COMMUNICATION SYSTEMS LTD - BLUESOFT SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA - DELOITTE CONSULTING & ADVISORY - - - EUR 1 692 000 - - - A Framework for Pairing Circular Economy and IoT: IoT as an enabler of the Circular Economy circularity-by-design as an enabler for IoT (CE-IoT) - - - EUR 1 692 000 - - - France - United Kingdom - Greece - Cyprus - Poland - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The overall aim of CE-IoT is to develop an innovative framework of interplay between Circular Economy and IoT, to explore novel ways in which this interaction can drastically change the nature of products, services, business - models and ecosystems. The CE-IoT framework will be bi-dimensional and bi-directional in terms of circularity, aiming to develop (i) novel circular economy business models and service supply chains to unlock CE-IoT synergies in order to generate - direct value for customers/end-users and augmenting resource productivity across economies by forming new ecosystems that eliminate both negative externalities and the need for considerable resources altogether, and (ii) open, circular-by-design IoT - architecture, where “smart” IoT objects (e.g., sensors, devices, systems and components) are integrated in the IoT ecosystem through patterns with proven key circularity-enabling properties (scalable connectivity, end-to-end security/privacy, - dependability and interoperability) to maximize IoT resource and data harvesting in a new breed of circular-by-design IoT ecosystems. - - 2022-06-30, Grant Agreement signed - - - 2018-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - France - - - CE-IOT - - - H2020-MSCA-RISE-2017 - - - 777855 - - - - - UNIVERSIDAD DE GRANADA - ASOCIACION ARTE TECNOLOGIA Y SOCIEDAD ARTES - ENGINLIFE-ENGINEERING SOLUTIONS - UNIVERSITA DEGLI STUDI DI ENNA KORE - ZEPHYRO SPA - ASSOCIAZIONE MICROCOSMI ONLUS - CTADVENTURE SP ZOO - ATHINA-EREVNITIKO KENTRO KAINOTOMIAS STIS TECHNOLOGIES TIS PLIROFOFORIAS, TON EPIKOLNONION KAI TIS GNOSIS - - - EUR 1 296 000 - - - loW Altitude Remote sensing for the Monitoring of the state of Cultural hEritage Sites: building aninTegrated model for maintenance. - - - EUR 1 296 000 - - - Spain - Spain - Italy - Italy - Italy - Italy - Poland - Greece - - - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - - WARMEST strategic goal is to create a novel comprehensive Decision Support System that will carry out a Cultural Heritage Risk Analsys (CHRA) and suggest improvements in maintenance and disaster management procedures for - cultural and natural heritage sites. The maintenance and disaster management plans developed with the support of the Decision Support System, will consider current and future scenarios, setting priorities for the actions to be taken, both on economic - and art historical grounds, delivering required information where and when needed, in a user-friendly way. To this end the consortium will develop new technologies to collect data on the conservation status of the sites and new tools to analyse it, - as there is presently a lack of data that is specifically relevant to understanding climate change impacts; these technologies in case of emergence, can help to assess the impact of events quickly and on large areas. WARMEST is challenging from a - management and from an engineering point of view, given that regulations are strict (to preserve the natural, archaeological and historical values), the factors to take into consideration are complex and not homogenous (technical, economic, - historical), the information to deliver differentiated according to users and concise or detailed when needed. The goals set by WARMEST can be met only by creating an heterogeneus consortium, involving knowledgeable experts from various fields from - private and public institutions. 9 beneficiaries will participate to the WARMEST consortium; 3 academic institutions, 2 association involved in heritage management and 4 private companies. 4 end users will be commited to the project as external - partners to obtain the right mixing of knowledge. - - 2021-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Spain - - - Warmest - - - H2020-MSCA-RISE-2017 - - - 777981 - - - - - ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON - GEORG-AUGUST-UNIVERSITAT GOTTINGENSTIFTUNG OFFENTLICHEN RECHTS - CONSIGLIO NAZIONALE DELLE RICERCHE - UNIWERSYTET WARSZAWSKI - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH - ATHINA-EREVNITIKO KENTRO KAINOTOMIAS STIS TECHNOLOGIES TIS PLIROFOFORIAS, TON EPIKOLNONION KAI TIS GNOSIS - UNIVERSITAET BIELEFELD - UNIVERSIDADE DO MINHO - STICHTING EIFL.NET - UNIVERSITEIT GENT - UNIVERSITETET I OSLO - COAR E.V. - COOPERACION LATINOAMERICANA DE REDES AVANZADAS - KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW - THE UNIVERSITY OF EDINBURGH - UNIVERSITY OF GLASGOW - ELLINOGERMANIKI AGOGI SCHOLI PANAGEA SAVVA AE - RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN - ETHNIKO IDRYMA EREVNON - OPEN LIBRARY OF HUMANITIES - DIGITAL RESEARCH INFRASTRUCTURE FOR THE ARTS AND HUMANITIES - UNIVERSITAT WIEN - INSTITUTE OF MATHEMATICS AND INFORMATICS AT THE BULGARIAN ACADEMY OF SCIENCE - RUDER BOSKOVIC INSTITUTE - UNIVERSITY OF CYPRUS - SYDDANSK UNIVERSITET - TARTU ULIKOOL - HELSINGIN YLIOPISTO - CONSORTIUM UNIVERSITAIRE DE PUBLICATIONS NUMERIQUES COUPERIN - UNIVERSITAT KONSTANZ - DEBRECENI EGYETEM - LANDSPITALI UNIVERSITY HOSPITAL - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - BAR ILAN UNIVERSITY - LATVIJAS UNIVERSITATE - KAUNO TECHNOLOGIJOS UNIVERSITETAS - UNIVERSITE DU LUXEMBOURG - UNIVERSITA TA MALTA - TECHNISCHE UNIVERSITEIT DELFT - Unitatea Executiva pentru Finantarea Invatamantului Superior, a Cercetarii, Dezvoltarii si Inovarii - UNIVERZITET U BEOGRADU - CENTRUM VEDECKO TECHNICKYCH INFORMACII SLOVENSKEJ REPUBLIKY - UNIVERZA V LJUBLJANI - FUNDACION ESPANOLA PARA LA CIENCIA Y LA TECNOLOGIA - KUNGLIGA BIBLIOTEKET - UNIVERSITAT ZURICH - IZMIR INSTITUTE OF TECHNOLOGY - JISC LBG - - - EUR 9 999 997,50 - - - OpenAIRE Advancing Open Scholarship - - - EUR 9 999 997,50 - - - Greece - Germany - Italy - Poland - Switzerland - Greece - Germany - Portugal - Netherlands - Belgium - Norway - Germany - Uruguay - Netherlands - United Kingdom - United Kingdom - Greece - Germany - Greece - United Kingdom - France - Austria - Bulgaria - Croatia - Cyprus - Denmark - Estonia - Finland - France - Germany - Hungary - Iceland - Ireland - Israel - Latvia - Lithuania - Luxembourg - Malta - Netherlands - Romania - Serbia - Slovakia - Slovenia - Spain - Sweden - Switzerland - Turkey - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - Other - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Other - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - - OpenAIRE-Advance continues the mission of OpenAIRE to support the Open Access/Open Data mandatesinEurope. By sustaining the current successful infrastructure, comprised of a human network and robust technical services, it - consolidates its achievements while working to shift the momentum among its communities to Open Science, aiming to be a trusted e-Infrastructurewithin the realms of the European Open Science Cloud.In this next phase, OpenAIRE-Advance strives to - empower its National Open Access Desks (NOADs) so they become a pivotal part within their own national data infrastructures, positioningOA and open science onto national agendas. The capacity building activities bring together experts ontopical task - groups in thematic areas(open policies, RDM, legal issues, TDM), promoting a train the trainer approach, strengthening and expanding the pan-European Helpdesk with support and training toolkits, training resources and workshops.It examines key - elements of scholarly communication, i.e., co-operative OA publishing and next generation repositories, to develop essential building blocks of the scholarly commons.On the technical level OpenAIRE-Advance focuses on the operation and maintenance of - the OpenAIRE technical TRL8/9 services,and radically improvesthe OpenAIRE services on offer by: a) optimizing their performance and scalability, b) refining their functionality based on end-user feedback, c) repackagingthem into products, taking a - professional marketing approach with well-defined KPIs, d)consolidating the range of services/products into a common e-Infra catalogue to enable a wider uptake.OpenAIRE-Advancesteps up its outreach activities with concrete pilots with three major - RIs,citizen science initiatives, and innovators via a rigorous Open Innovation programme. Finally, viaits partnership with COAR, OpenAIRE-Advance consolidatesOpenAIRE’s global roleextending its collaborations with Latin America, US, Japan, Canada, - and Africa. - - 2020-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.3."> - - - EINFRA-12-2017 - Data and Distributed Computing e-infrastructures for Open Science - - - RIA - Research and Innovation action - - - Greece - - - OpenAIRE-Advance - - - H2020-EINFRA-2017 - - - 777541 - - - - - PERCUROS BV - ACADEMISCH ZIEKENHUIS LEIDEN - ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM - TECHNISCHE UNIVERSITEIT DELFT - UNIVERSITA DEGLI STUDI DI CAMERINO - TECOBIOSCIENCES GMBH - UNIVERSITEIT VAN AMSTERDAM - THE UNIVERSITY OF SHEFFIELD - UNIVERSITEIT MAASTRICHT - JENACELL GMBH - MEDRES-MEDICAL RESEARCH GMBH - AUGEAS ASSOCIAZIONE DI SPORT PROMOZIONE E TURISMO - PROGREDUM GMBH - ASSOCIAZIONE CULTURALE CASTELLI ROMANI GREEN TOUR - BOSCHIVA MELCHIORRI SRL - HELRIK AND LOUW COMPANY LTD - UNIWERSYTET JAGIELLONSKI - - - EUR 2 430 000 - - - Personalised Postoperative Immunotherapy To Improving Cancer Outcome and improving quality of life - - - EUR 2 430 000 - - - Netherlands - Netherlands - Netherlands - Netherlands - Italy - Germany - Netherlands - United Kingdom - Netherlands - Germany - Germany - Italy - Germany - Italy - Italy - United Kingdom - Poland - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - During this RISE project we aim to develop nanoparticle-based encapsulated libraries of different immunotherapeutic biomolecules for treatment after surgery as part of a novel cancer management strategy. The current - state-of-art for the management of cancer starts with surgery, after identification of an accessible tumour mass. Surgery remains an effective treatment option for many types of cancer today and it is considered curative treatment for most solid - tumours. It forms part of a multidisciplinary approach used in conjunction with radiotherapy or chemotherapy. These approaches, however, have several limitations, including inability of surgical resection to affect distal metastatic disease, toxicity - to healthy tissues with chemotherapy and lack of effectiveness of radiation therapy in more aggressive tumours. The observation that cancer can relapse months or years after initial surgery implies that micrometastases still resides within the body - in a latent state. Our proposal is to take cancer therapy to beyond state-of-art by implementing techniques which will take us into new directions. - - 2022-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Netherlands - - - CANCER - - - H2020-MSCA-RISE-2017 - - - 777682 - - - - - INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE - ASYMPTOTE LIMITED - UNIVERSIDADE DE COIMBRA - FUNDACIO INSTITUT DE CIENCIES FOTONIQUES - Universidade da Madeira - BIOSEARCH S.A. - INSTITUT DES SCIENCES ET INDUSTRIES DU VIVANT ET DE L'ENVIRONNEMENT - AGRO PARIS TECH - CLOCK-T - CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TECNICAS (CONICET) - - - EUR 634 500 - - - Preservation of microorganisms by understanding the protective mechanisms of oligosaccharides - - - EUR 634 500 - - - France - United Kingdom - Portugal - Spain - Portugal - Spain - France - France - Argentina - - - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - - Microorganisms offer a large variety of functionalities that remains under-exploited due to the current inability to perform long term preservation at an industrial scale. PREMIUM project is a four-year multidisciplinary - project involving a consortium of 5 academic partners from 5 European countries (France, Spain and Portugal) and 1 from third country (Argentina) and 3 industrial partners (France, United Kingdom and Spain). The project aims at developing new - strategies to preserve lactic acid bacteria from laboratory to industrial scale. The innovative approaches of the project lay on: i) producing oligosaccharides of original composition for protecting cells; ii) developing novel preservation process - based on encapsulation and evaluating the environmental impact of the whole system of production and stabilization of micro-organisms from the laboratory step iii) developing high-throughput characterization and screening tools such as vibrational - spectroscopy. A multicriteria analysis approach will be developed to identify the most promising strategies for industrial eco-friendly preservation of micro-organisms. - - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - France - - - PREMIUM - - - H2020-MSCA-RISE-2017 - - - 777657 - - - - - UNIVERSITA DEGLI STUDI DI TRENTO - UNIVERSIDADE DO MINHO - CHONBUK NATIONAL UNIVERSITY - CHULALONGKORN UNIVERSITY - MONGOLIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY - - - EUR 670 500 - - - Regenerative Medicine Innovation Crossing - Research and Innovation Staff Exchange inRegenerative Medicine - - - EUR 877 500 - - - Italy - Portugal - South Korea - Thailand - Mongolia - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Natural materials in biomedical field are investigated for clinical use, as materials for the fabrication of biomedical prostheses, for the stimulation of regenerative medicine patterns, or as carriers for drug release, and - have acquired increasing relevance in the past years, being recognized their intrinsic bioactive properties and the possibility to repair and overcome diseases with the use of Tissue Engineering and Regenerative Medicine (TERM) based procedures. - - 2021-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Italy - - - REMIX - - - H2020-MSCA-RISE-2017 - - - 778078 - - - - - UNIVERSITE D'ORLEANS - BODYCAP - STAFFORDSHIRE UNIVERSITY - PODO ACTIVA SL - Pontificia Universidad Catolica del Peru - PONTIFICIA UNIVERSIDAD JAVERIANA - UNIVERSITE IBNOU ZOHR A AGADIR - Hospital Nacional Dos de Mayo - - - EUR 504 000 - - - Smartphone Thermal ANalysis for Diabetic foot Ulcer Prevention and treatment - - - EUR 504 000 - - - France - France - United Kingdom - Spain - Peru - Colombia - Morocco - Peru - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Diabetic foot (DF) disease includes neuropathy, peripheral arterial disease and infection which may lead to ulceration and subsequent lower limb amputation. DF ulcers could be further reduced according to diabetes experts. - Temperature is one of the possible clinical parameter which is not currently well exploited. Recently, smartphones can acquire thermal images thanks to dedicated thermal camera. The STANDUP project proposes a smartphone based system such that mobile, - accurate, friendly, low cost and fast thermal analysis of the plantar foot surface can be achieved. The smartphone thermal imaging system will be composed of a smartphone and of a FlirOne thermal camera. In the STANDUP project, two smartphone - applications will be developed. The first one (A1: hyperthermia detection and analysis of thermal variations in time) will permit to detect possible hyperthermia of the plantar foot surface and will analyze temperature variations on targeted regions - of interest. The second smartphone application will assess temperature, color, and 3D shape of DF ulcer along time. These smartphone applications will be evaluated during clinical trials in hospitals. In the first clinical trial, a cold stress test - will permit to detect neuropathy and peripheral arterial disease. In the second clinical trial, temperature, color, and 3D shape in DF ulcers will be studied during its treatment. The third clinical study will assess the effectiveness of new insoles, - these new insole will be developed during STANDUP with the objective to relive hyperthermia in DF. These 2 smartphone applications will be enhanced to result in an advanced prototype of smartphone based system for the targeted medical applications. - This advanced smartphone thermal prototype, and the new insoles, will be developed during STANDUP to rapidly address novel market demands in DF early diagnosis, and in DF ulcer prevention and treatment and will lead to economic benefits for social - and healthcare system. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - France - - - STANDUP - - - H2020-MSCA-RISE-2017 - - - 777661 - - - - - UNIVERSIDADE DE AVEIRO - UNIVERSITAT DE VALENCIA - THE UNIVERSITY OF SHEFFIELD - UNIVERSIDAD NACIONAL AUTONOMA DE MEXICO - Universidade Federal do Pará - - - EUR 220 500 - - - Fundamental fields and compact objects: theory and astrophysical phenomenology - - - EUR 220 500 - - - Portugal - Spain - United Kingdom - Mexico - Brazil - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Epoch-making observational, theoretical and computational developments make this an exceptional time for the understanding of gravity in the strong field regime. The recent detection of gravitational waves (GWs), together with - other ongoing experiments; the discovery of unexpected compact objects in General Relativity (GR); and the breakthroughs in the field of Numerical Relativity (NR), make strong gravity a central player in the scientific scene. Exploring different - scenarios in this context is timely and synergies are mandatory, for such an endeavor. - - 2021-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Portugal - - - FunFiCO - - - H2020-MSCA-RISE-2017 - - - 777740 - - - - - INSTITIUID TEICNEOLAIOCHTA BHAILE ATHA CLIATH - INSTITUT DE RECHERCHE ET D'INNOVATION - UNIVERSITY OF DURHAM - DUBLIN CITY COUNCIL - COMMUNAUTE D'AGGLOMERATION PLAINE COMMUNE - UNIVERSIDAD DE LAS ARTES - - - EUR 463 500 - - - Real Smart City - - - EUR 463 500 - - - Ireland - France - United Kingdom - Ireland - France - Ecuador - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - - The overarching objective of the ReaLsMs is to develop and implement a perspective on the Smart City through critical humanities research and innovation in the context of the Digital Studies. The joint research fields of - ReaLsMs will be the development of historical and philosophical underpinnings of the Data City and the implementation of the Smart City within local governance structures, including Dublin City Council and Plaine Commune (Paris North). Consisting of - a network of three academic partners in the EU, Dublin Institute of Technology - School of Creative Arts, Computer Science and Architecture, (DIT, IE), the Institut de Recherche et d’Innovation (IRI) at the Centre Pompidou (FR) and Durham University, - the Centre for Humanities Innovation (DU, UK). The 2 non-academic partners located in the EU are Dublin City Council (DCC, IE) and Plaine Commune (FR). The Third Country academic partners is the Universidad de las Artes in Ecuador (UA, Ecuador). The - purpose of developing this consortium as a Marie Sklodowska-Curie Research and Innovation Staff Exchange is to share knowledge across disciplines in order to develop transdisciplinary model for “real smart city,” which is defined as a Smart City that - is based on a critical humanities perspective, where citizens are the proper data brokers, engaging through public fora for debate and new technologies that enable citizen participation. Through a international and cross-sectoral network, the aim is - to across sectors, allowing academic researchers to work with civic government and data collection while non-academic partners can benefit from the insights of academic partners to create new forms of education that illuminate the “black box” of - Smart City technology. The expected outcome of research are a new transdisciplinary epsiteme of the Smart and Data City that is rooted in Digital Studies and subsequently informed methods for handling data collected through Smart City infrastructure. - - 2020-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Ireland - - - ReaLsMs - - - H2020-MSCA-RISE-2017 - - - 777707 - - - - - ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA - TEAGASC - AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY - CONSIGLIO NAZIONALE DELLE RICERCHE - UNIVERSITA TA MALTA - PROBIOTICAL SPA - ADVANCE SCIENCE (FORBAIRT EOLAIOCHTA TEO) LIMITED - NUTRI BIOTECH SERVICES LTD - CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TECNICAS (CONICET) - - - EUR 346 500 - - - Nourishing PRObiotics to Bees to Mitigate Stressors - - - EUR 346 500 - - - Italy - Ireland - Italy - Malta - Italy - Ireland - Malta - Argentina - - - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - - In the last decades, bees have been threatened by a number of biotic and abiotic stresses, which strongly affect beehives integrity. Consequently, the beekeeping sector together with ecosystem and agricultural sectors - depending on pollinators suffer of missed pollination. Nosema ceranae is a bee gut parasite that has received particular attention in the last years because it causes bee colonies to collapse due to energy and nutrient deficiency. Furthermore, the - bee gut microbiota undergoes a dysbiosis process following infection. N. ceranae virulence in infected bees escalates when forager bees uptake sub-lethal doses of insecticides such as Neonicotinoids from the polluted agricultural environment - surrounding the hive. The European Union banning of antibiotics for therapeutic use in the beekeeping sector approved in 2001 has deprived beekeepers of Fumagillin-B, the sole antibiotic previously available to control Nosema sp.. The need to find - alternative treatments to fight bee diseases has led researchers to the study of ecofriendly practices. Our proposed research aims to develop a strategy for the health of the bee gut based on microbial and plant resources to inhibit N. ceranae - proliferation and to mitigate the effect of synergic bee stressors. The project will be developed by a consortium formed by 4 research institutions and 3 SMEs of 3 different European countries and a third country (Argentina). Research institutions - will do the experimental work on bees aimed at the definition of a strategy based on the use of beneficial bacteria and plant extracts and at the evaluation of the impact on the bee gut of the developed formulation. SMEs will contribute to the choice - of the ingredients of the prototype formulation and at finding a strategy to produce it. ESR and ER will perform secondments in research institutions and SMEs to facilitate transfer of knowledge between the research and production sector. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Italy - - - NO PROBleMS - - - H2020-MSCA-RISE-2017 - - - 777760 - - - - - LATVIJAS UNIVERSITATE - KAUNO TECHNOLOGIJOS UNIVERSITETAS - LULEA TEKNISKA UNIVERSITET - USTAV POLYMEROV - SLOVENSKA AKADEMIA VIED - DANMARKS TEKNISKE UNIVERSITET - BALTIC SCIENTIFIC INSTRUMENTS SIA - MATERIALS RESEARCH CENTER - SYNPO AKCIOVA SPOLECNOST - UAB SPORTINE AVIACIJA IR KO - BELARUSIAN STATE UNIVERSITY - DREXEL UNIVERSITY - - - EUR 1 246 500 - - - MULTIFUNCTIONAL POLYMER COMPOSITES DOPED WITH NOVEL 2D NANOPARTICLES FOR ADVANCED APPLICATIONS - - - EUR 1 246 500 - - - Latvia - Lithuania - Sweden - Slovakia - Denmark - Latvia - Ukraine - Czech Republic - Lithuania - Belarus - United States - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - NANO2DAY is aiming at the development of advanced multifunctional composites with outstanding electronic and mechanical properties by incorporation of novel MXene nanosheets into polymer matrixes. The project will firstly go - forward to the rational design and systematic exploration of MXene-polymer nanocomposites for wearable electronics and advanced structural components for airspace applications. This will be achieved by i) intersectoral consolidation and sharing of - knowledge and expertise of 11 members from Europe and USA working in different areas and ii) collaborative research on the development and assessment of novel materials, including technology, characterisation, modelling, and validation. The concept - explored in the project accounts for finding and extending the application potential of MXene-doped polymers and validation of their effectiveness compared to well-known graphene-doped polymers. The innovative aspects followed in the project are - based on up-scaling of novel technologies for “close-to-industrial” synthesis of MXenes and MXene-doped polymer masterbatches and implementation of MXenes into design of structural polymer composites, including FRPs. NANO2DAY will essentially - contribute to the integration of scientific insights into innovation-based industrial environment and successful implementation of novel advanced materials into practical applications. - - 2022-04-30, Grant Agreement signed - - - 2018-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Latvia - - - NANO2DAY - - - H2020-MSCA-RISE-2017 - - - 777810 - - - - - UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA - UNIVERSITE GRENOBLE ALPES - AGGELIDIS I.-PALLIKARIDIS X. OE - TEATAR TSVETE - INSTITUT PO ROBOTIKA - TECHNOLOGIKO EKPEDEFTIKO IDRIMA ANATOLIKIS MAKEDONIAS & THRAKIS - CENTRE HOSPITALIER UNIVERSITAIRE DE GRENOBLE - CENTRO DE VISION POR COMPUTADOR - KOKURITSU DAIGAKU HOJIN KYUSHU KOGYO DAIGAKU - UNIVERSIDAD DE CHILE - UNIVERSITE HASSAN II DE CASABLANCA - - - EUR 1 296 000 - - - Cyber-Physical Systems for PEdagogical Rehabilitation in Special EDucation - - - EUR 1 386 000 - - - Spain - France - Greece - Bulgaria - Bulgaria - Greece - France - Spain - Japan - Chile - Morocco - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Research Organisations - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The aim of the current MSCA RISE project CybSPEED is to advance a novel framework for analysis, modelling, synthesis and implementation of Cyber-Physical Systems for pedagogical rehabilitation in special education, based on a - combination of the best of experience and achievements of the partners in the domains of brain-aware robotics, cognitive biometrics, computational intelligence and reasoning in humanoid and non-humanoid robots for education. CybSPEED project builds - on the results and insights of the recently completed project funded by EEA Grant of Bulgaria and Norway "METEMSS: Methodologies and technologies for enhancing the motor and social skills of children with developmental problems" (IR-BAS), on a - logical projection of the EU funded project "Social & Smart", called “Storytelling NAO” of Spain (UPV/EHU) and on the ongoing research of the project “Special Education Robot Teaching Assistant (EduBot)” of Greece (EMaTTech) funded by the Stavros - Niarchos Foudation. CybSPEED project emphasizes the intrinsic-motivational approach to learning by designing human-robot situations (games, pedagogical cases, artistic performances) and advanced interfaces (brain-computer, eye-gaze tracking and - virtual reality) where children and students interact with the novel technology to enhance the underlying self-compensation and complementarity of brain encoding during learning. The CybSPEED project aspires to establish as well as to sustain an - innovation network across the EU, Japan in the Far East, Chile in South America and Morocco in West Africa that will pursue top-level research on three levels – 1) analysis of cognitive biometrics signals, 2) modeling of the learner-robot interaction - and 3) development of novel instruments toward an optimal design of Cyber-Physical Systems for improved pedagogical rehabilitation in education. - - 2021-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Spain - - - CybSPEED - - - H2020-MSCA-RISE-2017 - - - 777720 - - - - - UNIVERSIDAD DE MALAGA - DEKRA TESTING AND CERTIFICATION SAU - Teknologian tutkimuskeskus VTT Oy - PIETRZYK SLAWOMIR - TIME.LEX - NORDUNET A/S - - - EUR 2 047 937,50 - - - Design of the European mobile network operator for research - - - EUR 2 047 937,50 - - - Spain - Spain - Finland - Poland - Belgium - Denmark - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - - The objective of EuWireless proposal is to develop the design of the first pan-European infrastructure to support research in mobile communication networks using regulated spectrum, with the goal of contributing to keep - Europe’s leadership in mobile communication technologies. The output of the project will be a complete design report addressing the pan-European operator, the regulatory aspects, the business model, the technical solutions and the roadmap for - implementation of the proposed infrastructure, as well as prototypes that confirm its feasibility. - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-01-2017 - Design Studies - - - RIA - Research and Innovation action - - - Spain - - - EuWireless - - - H2020-INFRADEV-2017-1 - - - 777517 - - - - - SCIENCE AND TECHNOLOGY FACILITIES COUNCIL - THE BRITISH LIBRARY BOARD - MONASH UNIVERSITY - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH - DATACITE – INTERNATIONAL DATA CITATION INITIATIVE - EUROPEAN MOLECULAR BIOLOGY LABORATORY - UNIVERSITAET BREMEN - PUBLIC LIBRARY OF SCIENCE - PUBLISHERS INTERNATIONAL LINKING ASSOCIATION INC NON PROFIT CORPORATION - ORCID INC. - KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW - HINDAWI LIMITED - - - EUR 4 998 650 - - - Connected Open Identifiers for Discovery, Access and Use of Research Resources - - - EUR 5 246 117,50 - - - United Kingdom - United Kingdom - Australia - Switzerland - Germany - Germany - Germany - United States - United States - United States - Netherlands - United Kingdom - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Other - Other - Other - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The goal of the FREYA consortium is to iteratively extend a robust environment for Persistent Identifiers (PIDs) into a core component of European and global research e-infrastructures. The resulting FREYA services will cover - a wide range of resources in the research and innovation landscape and enhance the links between them so that they can be exploited in many disciplines and research processes. This will provide an essential building block of the European Open Science - Cloud (EOSC). Moreover, the FREYA project will establish an open, sustainable, and trusted framework for collaborative self-governance of PIDs and services built on them. - - 2020-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.3."> - - - EINFRA-21-2017 - Platform-driven e-infrastructure innovation - - - RIA - Research and Innovation action - - - United Kingdom - - - FREYA - - - H2020-EINFRA-2017 - - - 777523 - - - - - UNIVERSITAET STUTTGART - SWEDISH SPACE CORPORATION - EBERHARD KARLS UNIVERSITAET TUEBINGEN - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 3 009 563,61 - - - European Stratospheric Balloon Observatory Design Study - - - EUR 3 267 158,11 - - - Germany - Sweden - Germany - Germany - Spain - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - - Following the findings of the H2020-funded ORISON project, we propose the design and development of a new European astronomical research infrastructure for stratospheric balloon-based telescopes. Our approach is to provide a - versatile community-accessible observatory capable of covering unserved scientific needs, including those of star- and planet formation studies and exoplanet research. These are particularly associated with requirements for high spatial and spectral - resolution far-infrared (FIR) observations, high sensitivity UV observations, and highly accurate visible light photometry. To a certain extent, these needs could also be addressed by space missions. A balloon infrastructure, however, will offer a - more cost-efficient and flexible approach, allowing instruments more adaptable to evolving needs (exchangeable and less risk-adverse), longer overall observation times (possibility to refill cooling fluids), and larger mirror sizes (less severe - launcher restrictions). So far, stratospheric telescopes, with the exception of SOFIA, have mostly served a single purpose and did not fly more than a few times. The proposed infrastructure, in contrast, will provide regular flights, allowing it to - operate as a true observatory. - - 2021-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-01-2017 - Design Studies - - - RIA - Research and Innovation action - - - Germany - - - ESBO DS - - - H2020-INFRADEV-2017-1 - - - 777516 - - - - - EUROPEAN FUTURE INNOVATION SYSTEM CENTRE - CSIL - CENTRO STUDI INDUSTRIA LEGGERA SOCIETA' COOPERATIVA - FONDATION EUROPEENNE DE LA SCIENCE - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - EUROPEAN MOLECULAR BIOLOGY LABORATORY - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH - CONSORCIO PARA LA CONSTRUCCION EQUIPAMIENTO Y EXPLOTACION DEL LABORATORIO DE LUZ SINCROTRON - STIFTUNG DEUTSCHES ELEKTRONEN-SYNCHROTRON DESY - - - EUR 1 498 717,50 - - - Charting Impact Pathways of Investment in Research Infrastructures - - - EUR 1 498 717,50 - - - Belgium - Italy - France - Germany - Germany - Switzerland - Spain - Germany - - - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - - The aim of the project is to develop a model describing the socio-economic impact of research infrastructures and of their related financial investments. The model will be developed in a modular manner adapting it to a broad - range of scientific domains and types of infrastructures. The project outcomes are expected to contribute to a common approach at international level and facilitate investments in research infrastructures by funding agencies and other stakeholders. - The project activities will take into account the work of the Research Infrastructure Socio-Economic Impact Working group, being established by the OECD Global Science Forum, and involve major key international players in this domain. More - specifically RI Impact Pathways project plans to carry out a comprehensive stocktaking exercise on the existing approaches for impact assessment of research infrastructures and map the current and future data gathering needs of the key stakeholder - groups. The goal is to identify the strengths and limitations of the existing approaches, detect existing gaps and overlaps, as well as to assess the level of complexity of the developed conceptual advances. Further a set of activities will be - devoted to map the needs of various stakeholders associated with IA of RIs. Employing participatory and systems thinking approaches the project will develop a modular impact assessment model that represents all major impact pathways of distinct types - of research infrastructures. The IA model will be put to practice by defining a set of reference indicators, providing guidance on the most appropriate monitoring and evaluation approaches and testing its feasibility with pilot research - infrastructures. The outcomes of the validated model will be integrated with the ESF MERIL platform that is authoritative and exhaustive online source of scientific and policy relevant data on research infrastructures in Europe. - - 2020-06-30, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.3.1., H2020-EU.1.4.1.3., H2020-EU.1.4.3.2."> - - - INFRASUPP-02-2017 - Policy and international cooperation measures for research infrastructures - - - CSA - Coordination and support action - - - Belgium - - - RI Impact Pathways - - - H2020-INFRASUPP-2017-1 - - - 777563 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - LABORATORIO DE INSTRUMENTACAO E FISICA EXPERIMENTAL DE PARTICULAS - ISTITUTO NAZIONALE DI FISICA NUCLEARE - INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK - KARLSRUHER INSTITUT FUER TECHNOLOGIE - UNIVERSITAT POLITECNICA DE VALENCIA - CESNET ZAJMOVE SDRUZENI PRAVNICKYCH OSOB - USTAV INFORMATIKY, SLOVENSKA AKADEMIA VIED - ATOS SPAIN SA - HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH - - - EUR 2 988 750 - - - Designing and Enabling E-infrastructures for intensive Processing in a Hybrid DataCloud - - - EUR 2 988 750 - - - Spain - Portugal - Italy - Poland - Germany - Spain - Czech Republic - Slovakia - Spain - Germany - - - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - - The key concept proposed in the DEEP Hybrid DataCloud project is the need to support intensive computing techniques that require specialized HPC hardware, like GPUs or low latency interconnects, to explore very large datasets. - A Hybrid Cloud approach enables the access to such resources that are not easily reachable by the researchers at the scale needed in the current EU e-infrastructure. - - - 2020-04-30, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.3."> - - - EINFRA-21-2017 - Platform-driven e-infrastructure innovation - - - RIA - Research and Innovation action - - - Spain - - - DEEP-HybridDataCloud - - - H2020-EINFRA-2017 - - - 777435 - - - - - ECOLE D'ECONOMIE DE PARIS - UNIVERSITEIT ANTWERPEN - JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN - ERASMUS UNIVERSITEIT ROTTERDAM - UNIWERSYTET EKONOMICZNY WE WROCLAWIU - THE QUEEN'S UNIVERSITY OF BELFAST - KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW - UNIVERSIDAD CARLOS III DE MADRID - UNIVERSITE DE ROUEN NORMANDIE - INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE RENNES - GESIS-LEIBNIZ-INSTITUT FUR SOZIALWISSENSCHAFTEN EV - - - EUR 3 385 610 - - - Historical high-quality company-level data for Europe - - - EUR 3 385 860 - - - France - Belgium - Germany - Netherlands - Poland - United Kingdom - Netherlands - Spain - France - France - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - EURHISFIRM designs a world-class research infrastructure (RI) to connect, collect, collate, align, and share detailed, reliable, and standardized long-term financial, governance, and geographical data on European companies. - EURHISFIRM enables researchers, policymakers, and other stakeholders to develop and evaluate effective strategies to promote investment, economic growth and job creation. The RI provides the tools for long-term analysis highlighting the dynamics of - the past and the way those dynamics structure our present and future. A few large stand-alone long-term databases have been built in Europe so far, while important resources have been invested into scattered and dispersed historical datasets. - EURHISFIRM develops innovative models and technologies to spark a “Big data” revolution in historical social sciences and valorize Europe’s cultural heritage. These technologies match and collate historical data, and connect them to recent ones. They - bring the next generation of data extraction and enrichment systems from digitized historical sources and web-based resources. The scaling up in the variety, quantity and quality of long-term data changes the way of conducting scientific enquiry in - the historical social sciences. EURHISFIRM constitutes a vibrant and large users’ community around the innovative data and services provided. The 2016 ESFRI Roadmap identifies Big Data, interdisciplinarity and innovative ways to disseminate research - products as the main science drivers for RIs in the Social Sciences and Humanities. It recognizes the need and the opportunity for RIs providing access to the European Cultural Heritage and innovative methods to analyze and integrate information - extracted to broad communities. EURHISFIRM fulfills this mission in close cooperation with ESFRI Landmark CESSDA and other existing RIs in the field of Arts and Humanities, like DARIAH, within the Research Data Alliance. - - 2021-03-31, Grant Agreement signed - - - 2018-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-01-2017 - Design Studies - - - RIA - Research and Innovation action - - - France - - - EURHISFIRM - - - H2020-INFRADEV-2017-1 - - - 777489 - - - - - ISTITUTO NAZIONALE DI FISICA NUCLEARE - UNIVERSIDAD DE CANTABRIA - STIFTUNG DEUTSCHES ELEKTRONEN-SYNCHROTRON DESY - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - AKADEMIA GORNICZO-HUTNICZA IM. STANISLAWA STASZICA W KRAKOWIE - ECRIN EUROPEAN CLINICAL RESEARCH INFRASTRUCTURE NETWORK - STICHTING EGI - - - EUR 3 077 000 - - - eXtreme DataCloud - - - EUR 3 396 875 - - - Italy - Spain - Germany - Switzerland - France - Poland - France - Netherlands - - - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Other - Other - - The eXtreme DataCloud (XDC) project will develop scalable technologies for federating storage resources and managing data in highly distributed computing environments. The services provided will be capable of operating at the - unprecedented scale required by the most demanding, data intensive, research experiments in Europe and Worldwide. XDC will be based on existing tools (TRL8+) that the project will enrich with new functionalities and plugins already available as - prototypes (TRL6). The targeted platforms are the current and next generation e-Infrastructures deployed in Europe, such as the European Open Science Cloud (EOSC), the European Grid Infrastructure (EGI), the Worldwide LHC Computing Grid (WLCG) and - the computing infrastructures that will be funded by the upcoming H2020 EINFRA-12 call. The main high-level topics addressed by the project include: federation of storage resources with standard protocols, smart caching solutions, policy driven data - management based on Quality of Service, data lifecycle management, metadata handling and manipulation, data preprocessing and encryption during ingestion, optimized data management based on access patterns. All the developments will be driven and - tested against real life use cases provided by the consortium partners representing research communities belonging to a variety of scientific domains: Life Science, Astrophysics, High Energy Physics, Photon Science and Clinical Research. The XDC - software will be released as Open Source platforms available for general exploitation. - - 2020-01-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.3."> - - - EINFRA-21-2017 - Platform-driven e-infrastructure innovation - - - RIA - Research and Innovation action - - - Italy - - - XDC - - - H2020-EINFRA-2017 - - - 777367 - - - - - UNIVERSITA DEGLI STUDI DI CATANIA - MARTIN-LUTHER-UNIVERSITAET HALLE-WITTENBERG - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - Faculdade de letras da Universidade de Lisboa - UNIVERSIDAD DE BUENOS AIRES - CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TECNICAS (CONICET) - UNIVERSIDADE FEDERAL DE SANTA CATARINA. - UNIVERSIDADE FEDERAL DE MINAS GERAIS - - - EUR 544 500 - - - Kant in South America - - - EUR 738 000 - - - Italy - Germany - United Kingdom - Portugal - Argentina - Argentina - Brazil - Brazil - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - A consortium of 4 EU Universities and 4 Southern American (SA) academic institutions analyze critically the development of Kant scholarship in Southern America in the last 15 years, following the booming of Kant studies in - that continent over that period and the exponential increase of its quality. Top SA Kant scholars are enrolled in the project that promises to enlarge greatly the competence of EU colleagues and in turn profit from their feedback. Early stage - researchers from both ends also take part to the exchange. The consortium builds on a web of established relations of most of the participants, at the personal and institutional level. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Italy - - - KANTINSA - - - H2020-MSCA-RISE-2017 - - - 777786 - - - - - TRUST-IT SERVICES LIMITED - GEORG-AUGUST-UNIVERSITAT GOTTINGENSTIFTUNG OFFENTLICHEN RECHTS - ROYAL IRISH ACADEMY - RESEARCH DATA ALLIANCE FOUNDATION - THE UNIVERSITY OF EDINBURGH - - - EUR 3 500 000 - - - The European plug-in to the global Research Data Alliance - - - EUR 3 500 000,50 - - - United Kingdom - Germany - Ireland - United Kingdom - United Kingdom - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - - RDA Europe 4.0 addresses the INFRASUPP-02-2017 call targeting the area “European support to the Research Data Alliance, RDA” designing Europe’s contribution to implementation of an effective governance model and strategy in - RDA global, while ensuring that RDA delivers on locally relevant issues. RDA Europe 4.0 focuses on the need for open and interoperable sharing of research data & on the need to build social, technical and cross-disciplinary links to enable such - sharing on a global scale. It strives to do this with its community-driven and bottom-up approach launched since 2012. In fact, RDA Europe 4.0 directly builds on the current RDA Europe effort, by efficiently bringing in the organisations that - implemented RDA Europe since 2012. - - 2020-05-31, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.3.1., H2020-EU.1.4.1.3., H2020-EU.1.4.3.2."> - - - INFRASUPP-02-2017 - Policy and international cooperation measures for research infrastructures - - - CSA - Coordination and support action - - - United Kingdom - - - RDA Europe 4.0 - - - H2020-INFRASUPP-2017-1 - - - 777388 - - - - - INSTYTUT PODSTAWOWYCH PROBLEMOW TECHNIKI POLSKIEJ AKADEMII NAUK - AGENZIA PER LA PROMOZIONE DELLA RICERCA EUROPEA - NATIONAL AUTHORITY FOR TECHNOLOGICAL INNOVATION - NEMZETI KUTATASI FEJLESZTESI ES INNOVACIOS HIVATAL - VEREIN EURESEARCH - SIHTASUTUS EESTI TEADUSAGENTUUR - AGENCIJA ZA MOBILNOST I PROGRAME EUROPSKE UNIJE - ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS - IDRYMA PROOTHISIS EREVNAS - UNIVERSITATEA DE STIINTE AGRICOLE SI MEDICINA VETERINARA A BANATULUI REGELE MIHAI I AL ROMANIEI DIN TIMISOARA - TURKIYE BILIMSEL VE TEKNOLOJIK ARASTIRMA KURUMU - IRISH UNIVERSITIES ASSOCIATION - OESTERREICHISCHE FORSCHUNGSFOERDERUNGSGESELLSCHAFT MBH - BULGARIAN ACADEMY OF SCIENCES - ACADEMY OF SCIENTIFIC RESEARCH AND TECHNOLOGY ASRT - DEUTSCHES ZENTRUM FUER LUFT - UND RAUMFAHRT EV - FUNDACION ESPANOLA PARA LA CIENCIA Y LA TECNOLOGIA - MINISTERIO DE EDUCACION Y CULTURA - RANNSOKNAMIDSTOD ISLANDS - - - EUR 1 800 000 - - - Network of the Marie Skłodowska-Curie Action National Contact Points for the mobile scientific and innovation community - - - EUR 1 800 000 - - - Poland - Italy - Israel - Hungary - Switzerland - Estonia - Croatia - Greece - Cyprus - Romania - Turkey - Ireland - Austria - Bulgaria - Egypt - Germany - Spain - Uruguay - Iceland - - - Research Organisations - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Other - Other - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Other - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - The National Contact Points (NCPs) play an important role in assisting potential applicants and project beneficiaries during their journey through the Horizon 2020 instruments. According to the EC Guide on the NCPs principles, - they are responsible for raising awareness about available funding opportunities; advising and training potential applicants in the preparation, submission and follow-up of their grant proposals; providing support during the project execution as well - as giving feedback on difficulties in the programme implementation. Thus, the NCPs constitute the main interface between the Programme and the R&I community in Europe and beyond, as well as between them and the EC. Basing on such a position, - Net4Mobility+ aims at strengthening the consistency and professionalism of the NCPs for Marie Skłodowska-Curie Actions – part of H2020 supporting international and intersectoral mobility and researchers’ career development. The consortium of 19 - beneficiaries and 6 associated partners representing the Member States, Associated and Third countries will execute a set of activities tailored to the nature of MSCA and to priorities and capacity of the entire NCPs network, including needs of the - “widening countries”. The focus on sharing expertise and good practices, transfer of knowledge to less experienced NCPs, joint support provided on a daily basis, enhancing knowledge and skills, broadening tools and methodology will facilitate the - improvement of the overall professionalism of NCP services across and outside Europe. Outcomes of project events (training, twinning, seminars), jointly developed materials (guides, recommendations) and communication and dissemination platform - (website, social media) will result in lowering entry barriers for newcomers, simplifying access to MSCA calls and raising the quality of applications. For reaching the project objectives and ensuring the impact, the consortium will work closely, - keeping high management and quality standards. - - 2021-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.5."> - - - MSCA-NCP-2017 - MSCA National Contact Points - - - CSA - Coordination and support action - - - Poland - - - Net4MobilityPlus - - - H2020-MSCA-NCP-2017 - - - 785632 - - - - - GOETEBORGS UNIVERSITET - GOETEBORGS UNIVERSITET - - - EUR 149 700,75 - - - Identification of novel inhibitors to prevent microbial production of pro-diabetic metabolites - - - EUR 149 700,75 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The gut microbiota has been associated with metabolic diseases, such as type 2 diabetes. In my ERC consolidator award we demonstrated that the gut microbiota is altered following bariatric surgery and that the altered - microbiota may be directly linked to some of the metabolic improvements observed following surgery. Interestingly, improved metabolism was associated with altered metabolite production capacity from the microbiota and we observed that a metabolite, - imidazole propionate, was reduced after surgery. In associated projects we have demonstrated that imidazole propionate is associated with type 2 diabetes in humans and induce insulin resistance in primary hepatocytes and when injected into mice. - Imidazole propionate is synthesized by the microbial enzyme UrdA from histidine. This POC will explore the potential of identifying inhibitors of UrdA to reduce production of imidazole propionate and thereby improve insulin sensitivity. If successful - we envision a new class of diabetes medication based on the concept of drug the bug. - - 2019-05-31, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Sweden - - - Drug the bug - - - ERC-2017-PoC - - - 780659 - - - - - INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE - INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE - - - EUR 150 000 - - - Innovative Antibiotics to target drug-resistant microbes - - - EUR 150 000 - - - France - France - - - Research Organisations - Research Organisations - - Antibiotic resistance has become a major public health threat in Europe and the United States where resistant bacteria are directly responsible for ten of thousands deaths per year. The D_Bug project aims to develop innovative - antibiotics to target drug-resistant microbes. - - 2019-04-30, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - France - - - D_Bug - - - ERC-2017-PoC - - - 780383 - - - - - UNIVERSITAET REGENSBURG - UNIVERSITAET REGENSBURG - - - EUR 1 955 846,25 - - - Metal-Mediated Methods for the Functionalization of White Phosphorus (P4) - - - EUR 1 955 846,25 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Organophosphorus compounds are an important and industrially relevant class of molecules with numerous uses, e.g. as reagents in organic synthesis, ligands in catalytically active metal complexes, and in pest control. - State-of-the-art synthesis methods for all these valuable and useful compounds rely on an atom inefficient and hazardous multi-step procedure involving the oxidation of white phosphorus (P4) with toxic chlorine gas. Less wasteful and more - environmentally benign methods are highly desirable, but transformations of white phosphorus directly into organophosphorus compounds are hardly developed. - - 2023-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - FunctionalP4 - - - ERC-2017-COG - - - 772299 - - - - - ISTITUTO EUROPEO DI ONCOLOGIA SRL - ISTITUTO EUROPEO DI ONCOLOGIA SRL - - - EUR 150 000 - - - Immuno-targeting of human AML quiescent cells by a novel phage display approach. - - - EUR 150 000 - - - Italy - Italy - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - One main objective of our ERC Advanced Grant project (InMec, No 341131) was to determine how cancer stem cells (CSCs) contribute to tumour growth, and the relative impact of quiescent versus proliferative CSCs. - - - 2019-06-30, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Italy - - - ITHACA - - - ERC-2017-PoC - - - 779802 - - - - - STICHTING ASTRON, NETHERLANDS INSTITUTE FOR RADIO ASTRONOMY - UNIVERSITAET BIELEFELD - CENTRUM BADAN KOSMICZNYCH POLSKIEJ AKADEMII NAUK - STICHTING INTERNATIONAL LOFAR TELESCOPE - OBSERVATOIRE DE PARIS - CHALMERS TEKNISKA HOEGSKOLA AB - SCIENCE AND TECHNOLOGY FACILITIES COUNCIL - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - - - EUR 2 998 750 - - - LOFAR for Space Weather - - - EUR 2 998 750 - - - Netherlands - Germany - Poland - Netherlands - France - Sweden - United Kingdom - Ireland - - - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - - TThe LOFAR for Space Weather (LOFAR4SW) design proposal will deliver the full conceptual and technical design for creating a new leading-edge European research facility for space weather science. - - 2021-05-31, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-01-2017 - Design Studies - - - RIA - Research and Innovation action - - - Netherlands - - - LOFAR4SW - - - H2020-INFRADEV-2017-1 - - - 777442 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - METEOROLOGISK INSTITUTT - ILMATIETEEN LAITOS - INSTITUT NATIONAL DE L ENVIRONNEMENT ET DES RISQUES INERIS - KONINKLIJK NEDERLANDS METEOROLOGISCH INSTITUUT-KNMI - STOCKHOLMS UNIVERSITET - UNIVERSITE GRENOBLE ALPES - LEIBNIZ INSTITUT FUER TROPOSPHAERENFORSCHUNG e.V. - UNIVERSIDAD DE CHILE - UNIVERSIDADE DE SAO PAULO - UNIVERSIDAD NACIONAL DE COLOMBIA - COMISION NACIONAL DE ENERGIA ATOMICA - UNIVERSIDAD MAYOR DE SAN ANDRES - UNIVERSIDAD TECNICA FEDERICO SANTA MARIA - INSTITUTO VENEZOLANO DE INVESTIGACIONES CIENTIFICAS - UNIVERSIDAD NACIONAL AUTONOMA DE MEXICO - UNIVERSIDAD DE PUERTO RICO - - - EUR 1 188 000 - - - Prediction of Air Pollution in Latin America - - - EUR 1 467 000 - - - Germany - France - Norway - Finland - France - Netherlands - Sweden - France - Germany - Chile - Brazil - Colombia - Argentina - Bolivia - Chile - Venezuela - Mexico - United States - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Other - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The overall objective of the PAPILA project (Prediction of Air Pollution in Latin America and the Caribbean) is to establish a sustained network of partners with complementary expertise, which will develop and implement an - analysis and forecast system for air quality with downscaling capability for Latin America and the Caribbean region (LAC region), and assess the impact of air pollution (background and peaks) on health and on the economy. This forecast system will - help decision-makers improve air quality and public health, and avoid the occurrence of acute air pollution episodes, particularly in urban areas. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Germany - - - PAPILA - - - H2020-MSCA-RISE-2017 - - - 777544 - - - - - MAGYAR TUDOMANYOS AKADEMIA RENYI ALFRED MATEMATIKAI KUTATOINTEZET - MAGYAR TUDOMANYOS AKADEMIA RENYI ALFRED MATEMATIKAI KUTATOINTEZET - - - EUR 1 386 363,52 - - - Noise-Sensitivity Everywhere - - - EUR 1 386 363,52 - - - Hungary - Hungary - - - Research Organisations - Research Organisations - - Noise-sensitivity of a Boolean function with iid random input bits means that resampling a tiny proportion of the input makes the output unpredictable. This notion arises naturally in computer science, but perhaps the most - striking example comes from statistical physics, in large part due to the PI: the macroscopic geometry of planar percolation is very sensitive to noise. This can be recast in terms of Fourier analysis on the hypercube: a function is noise sensitive - iff most of its Fourier weight is on "high energy" eigenfunctions of the random walk operator. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Hungary - - - NOISE - - - ERC-2017-COG - - - 772466 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UPPSALA UNIVERSITET - KUNGLIGA TEKNISKA HOEGSKOLAN - EUROPEAN SPALLATION SOURCE ERIC - UNIVERSITY OF CUKUROVA - UNIVERSIDAD AUTONOMA DE MADRID - "NATIONAL CENTER FOR SCIENTIFIC RESEARCH ""DEMOKRITOS""" - ISTITUTO NAZIONALE DI FISICA NUCLEARE - RUDER BOSKOVIC INSTITUTE - SOFIISKI UNIVERSITET SVETI KLIMENT OHRIDSKI - LUNDS UNIVERSITET - AKADEMIA GORNICZO-HUTNICZA IM. STANISLAWA STASZICA W KRAKOWIE - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH - UNIVERSITE DE GENEVE - UNIVERSITY OF DURHAM - - - EUR 2 999 018 - - - Feasibility Study for employing the uniquely powerful ESS linear accelerator to generate an intense neutrino beam for leptonic CP violation discovery and measurement. - - - EUR 4 671 583,68 - - - France - Sweden - Sweden - Sweden - Turkey - Spain - Greece - Italy - Croatia - Bulgaria - Sweden - Poland - Switzerland - Switzerland - United Kingdom - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - After the Big Bang, matter and antimatter were produced in equal quantities through materialization of the huge energy released. Observations show that today, however, there is a nearly total absence of antimatter in the - Universe. The occurrence of Charge-Parity Violation (CPV) is a necessary condition for an explanation of this absence. CPV has already been observed in the quark sector but the measured amount is insufficient to explain the observed matter-antimatter - asymmetry. Recent neutrino oscillation measurements indicate that the discovery of neutrino CPV becomes an important candidate to explain the observed matter dominance in the Universe. The goal of ESSnuSB project is to discover and measure neutrino - CPV with unprecedented sensitivity. The ESSnuSB concept takes advantage of two outstanding opportunities. The first is the construction in Europe of the European Spallation Source, ESS, the world’s most intense proton source, with a beam power almost - one order of magnitude higher than any other accelerator. The second is the recently measured unexpectedly large value of the oscillation mixing angle θ13. The latter fact implies that to obtain maximum sensitivity, the neutrino detector shall be - placed at the second neutrino oscillation maximum, not at the first as implemented by the other proposed experiments. The Garpenberg mine in Sweden, in which it is proposed to install the underground neutrino detector, is situated at a distance from - ESS that corresponds to the second maximum. The COST Action CA15139, “Combining forces for a novel European facility for neutrino-antineutrino symmetry-violation discovery”, already recognizes the necessity to have neutrino facilities in Europe. The - goal of the ESSνSB H2020 Design Study is to organize European physicists and accelerator engineers in co-operation with the ESS Laboratory and the Garpenberg Mining Company to study and produce a Conceptual Design Report for the ESSnuSB project. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-01-2017 - Design Studies - - - RIA - Research and Innovation action - - - France - - - ESSnuSB - - - H2020-INFRADEV-2017-1 - - - 777419 - - - - - UNIVERSITY OF LEEDS - UNIVERSITY OF LEEDS - - - EUR 1 965 623 - - - Deforestation – Climate –Atmospheric composition – Fire interactions and feedbacks - - - EUR 1 965 623 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Extensive and ongoing tropical deforestation and degradation have important environmental impacts. Smoke aerosol from deforestation fires degrades air quality, but the effects are poorly quantified. Deforestation alters - rainfall through changes in the land surface and through changes to atmospheric aerosol. The magnitude and the sign of the rainfall response is not clear, because of poor process-level understanding and because previous attempts have studied land - surface and aerosol responses separately. The impacts of deforestation on atmospheric composition and climate cause a complex set of biosphere interactions resulting in potential Earth system feedbacks. These feedbacks have not yet been quantified - and so their importance is not known. The full impact of deforestation on air quality, climate and the Earth System may have been underestimated because there have been no integrated studies of the combined interactions and feedbacks between - deforestation and the Earth system. DECAF is the first integrated study of the combined interactions and feedbacks between tropical deforestation, fire, atmospheric composition and climate. To address this important challenge, DECAF will exploit new - information from in-situ and satellite observations in combination with state-of-the-art numerical models. DECAF will deliver improved process-level knowledge of the impacts of deforestation on atmospheric composition and climate and a step change in - our understanding of the interactions and feedbacks between deforestation, atmospheric composition and climate. New understanding will inform the development of climate and Earth System Models and will facilitate new climate and Earth system - assessments. - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - DECAF - - - ERC-2017-COG - - - 771492 - - - - - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - - - EUR 150 000 - - - ViDaR: R-enabled large-scale data analytics in ViDa - - - EUR 150 000 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In this project we will build ViDaR, an interface for integrating R with ViDa. R is among the leading data analytics environments (the leading open-source), and is heavily used by data and domain scientists and data analysts - in their daily routine. ViDa, developed by an ERC grant, is the state-of-the-art query engine for raw data. It relies on data virtualization, i.e., abstracting data out of its form and manipulating it regardless of the way it is stored or structured, - to enable efficient, scalable, querying and manipulation of data in-situ, at their raw format and shape. Integration of ViDa with R will have a positive impact on both systems. For ViDa, it will provide capabilities for data exploration, - visualization, mining and analytics, as well as powerful libraries for numerical and statistical computing, thereby substantially growing its user base. For R, it will increase its scale and performance, and reduce the time and effort spent by data - scientists on tedious data management tasks. The resulting solution will serve as a proof-of-concept of ViDa’s performance, capabilities, and flexibility for integration with any third-party software that needs to manage vast amounts of raw data. - - 2019-06-30, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Switzerland - - - ViDaR - - - ERC-2017-PoC - - - 768910 - - - - - JUSTUS-LIEBIG-UNIVERSITAET GIESSEN - JUSTUS-LIEBIG-UNIVERSITAET GIESSEN - - - EUR 1 991 387,50 - - - Nuclear mRNA Packaging and mRNP Architecture - - - EUR 1 991 387,50 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - An important step of gene expression is the formation of a messenger ribonucleoprotein particle (mRNP). The messenger RNA (mRNA) is synthesized by RNA polymerase II transcribing a protein-coding gene. The mRNA is processed, - i.e. capped, spliced and polyadenylated, and packaged into an mRNP by binding of RNA-binding proteins (RBPs). The RBPs bound to the mRNA are essential for the stability of the mRNP, control nuclear mRNA export and often determine cytoplasmic - processes such as mRNA localization, translation and decay. Thus, the formation and composition of an mRNP is important for the posttranscriptional control of gene expression. Despite its essential nature, the mechanism of nuclear mRNP packaging and - the architecture of an mRNP are still poorly understood due to the fact that mRNPs contain many different mRNAs. The overall goal of this proposal is to elucidate the mechanism of mRNP formation and the molecular structure of an mRNP. Specifically, - - 2023-05-31, Grant Agreement signed - - - 2018-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - mRNP-PackArt - - - ERC-2017-COG - - - 772049 - - - - - THE UNIVERSITY OF EDINBURGH - THE UNIVERSITY OF EDINBURGH - - - EUR 148 914 - - - Rapid production of HUMAN MAST CELLS - - - EUR 148 914 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Mast cells are involved in the allergic response, anaphylaxsis, wound healing and angiogenesis. When activated via IgE, damage/pathogen-induced molecules or complement components, the granules of mast cells release proteases. - Dysregulation of mast cells is implicated in allergies of the skin and airways, autism, chronic fatigue syndrome, pain, mastocytoma and intestinal dysmotility. Strategies to limit the damaging effects of mast calls are needed. However, the - development of novel treatments is hampered by the inability to grow mast cells rapidly and efficiently in culture. Bone marrow cell cultures typically take 12 weeks before mast cells are available for study. Even then, there are too few cells to use - for drug discovery or patient-specific treatment strategies. Embryonic stem cells (ESC) represent an alternative method for the production of mast cells. An unexpected ground-breaking discovery from our ERC AdG 341096 studies aiming to produce - hematopoietic stem cells, was the development of a novel method that instead produces large numbers of mast cells in a short time. Mouse ESC engineered with a unique reporter gene that allows for cell enrichment during a multi-step culture yields a - homogenous population of phenotypic and functional connective tissue and mucosal mast cells. Within only 3 weeks large numbers of mast cells are generated. To translate this method for large scale rapid production of human mast cells we will 1) - characterize unique human reporter ESCs made by Crispr/CAS9 state-of-the-art method; 2) optimize human mast cell production from reporter hESCs in a multi-step differentiation culture; 3) characterize/validate the function of hESC-derived mast cells - (normal and mutant); 4) interact with industry to use hESC-derived mast cells for drug-discovery and studies of mast cell differentiation and dysfunction. Long-term goals include the development of mast cell treatment strategies for personalized - medicine. - - 2019-05-31, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - MASTFAST - - - ERC-2017-PoC - - - 768728 - - - - - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - - - EUR 1 994 385 - - - Imaging, Spectroscopy and Control of Quantum states in advanced Materials - - - EUR 1 994 385 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Atomic confinement in 2D materials, topological protection in strong spin-orbit coupling systems or chiral magnets, all result in spin/charge textured states of matter. For example skyrmions, a whirling distribution of spins, - behave as individual particles which controlled creation/annihilation/motion is of great importance in spintronics. To achieve control over skyrmions, or more generally over the constituents of disordered elastic media (vortices in superconductors, - domain walls in magnets to name a few), the fundamental interplay between short-range and long-range interactions, influenced by topological protection, disorder and confinement, has to be understood and manipulated. This project aims at controlling - with electromagnetic pulses a handful of charges and spins in nanostructured materials to be filmed with nm/fs resolution by time-resolved Transmission Electron Microscopy. I propose to image and shape confined electromagnetic fields (plasmons) in - nanostructured novel materials. With this ability, we will implement/demonstrate the ultrafast writing and erasing of individual skyrmions in topological magnets. These experiments will enable the fundamental investigation of defects in topological - networks and possibly seed new ideas for application in ultradense and ultrafast data storage devices. Similarly, pinning of vortices in type II superconductors will be controlled by light and imaged, gaining new insights into out of equilibrium - superconductivity. In my laboratory, shaping and filming plasmonic fields down to the nm-fs scales have been demonstrated, as well as laser-writing and imaging skyrmions in nanostructures. ISCQuM will allow implementing crucial advances: i) extending - our photoexcitation to the far-infrared for creating few-cycles electromagnetic pulses and exciting structural or electronic collective modes; ii) upgrading our detection to higher sensitivity and spatial resolution, extending our ability to image - spin and charge distributions. - - 2023-06-30, Grant Agreement signed - - - 2018-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Switzerland - - - ISCQuM - - - ERC-2017-COG - - - 771346 - - - - - INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE - INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE - - - EUR 149 866 - - - Vision and Hearing In Action Laboratory - - - EUR 149 866 - - - France - France - - - Research Organisations - Research Organisations - - The objective of VHIALab is the development and commercialization of software packages enabling a robot companion to robustly interact with multiple users. VHIALab builds on the scientific findings of ERC VHIA (February 2014 - - January 2019). Solving the problems of audio-visual analysis and interaction opens the door to multi-party and multi-modal human-robot interaction (HRI). In contrast to well investigated single-user spoken dialog systems, these problems are extremely - challenging because of noise, interferences and reverberation present in far-field acoustic signals, overlap of speech signals from two or more different speakers, visual clutter due to complex situations, people appearing and disappearing over time, - speakers turning their faces away from the robot, etc. For these reasons, today's companion robots have extremely limited capacities to naturally interact with a group of people. Current vision and speech technologies only enable single-user - face-to-face interaction with a robot, benefitting from recent advances in speech recognition, face recognition, and lip reading based on close-field microphones and cameras facing the user. As a consequence, although companion robots have an - enormous commercialization potential, they are not yet available on the consumer market. The goal of VHIALab is to further reduce the gap between VHIA's research activities and the commercialization of companion robots with HRI capabilities. We - propose to concentrate onto the problem of audio-visual detection and tracking of several speakers, to develop an associated software platform, to interface this software with a commercially available companion robot, and to demonstrate the project - achievements based on challenging practical scenarios. - - 2019-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - France - - - VHIALab - - - ERC-2017-PoC - - - 767064 - - - - - UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA - UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA - - - EUR 1 497 831 - - - A neurosplenic pathway coupling Immunity and Hypertension - - - EUR 1 497 831 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Hypertension (HTN) is a leading cause of morbidity and mortality worldwide. During past decades, several therapies have been developed to afford an optimal blood pressure (BP) regulation. However, the prevalence of - uncontrolled HTN continues to rise, with a number of patients still resistant to all ongoing antihypertensive treatments, raising unsolved mechanistic challenges. In the last years, the most attractive novelty in HTN postulated that immune system has - a crucial role in BP raising, as well as in end-organ damage. Several advances have been done in this field, but clear mechanistic explanations of how the immune system gets activated under hypertensive challenges is still unknown. It is becoming - increasingly clear that, even in the regulation of body hemodynamic, the immune system and the autonomic nervous system serve as two major “sensory organs” capable to be activated upon manifold hits that perturb homeostasis. SymPAtHY is a - multidisciplinary strategy aimed at discovering how nervous and immune systems couple in HTN. The concept of this project is to dissect the neuro-immune pathway responsible for BP rising and end-organ damage. The articulation in 3 MAIN AIMS will - allow to afford the mechanistic insights from different perspectives. The overall objectives are as follows: 1) Central nervous system relay station coupling immunity and hypertension. 2) Splenic immune mechanisms: from sympathetic drive to T cell - egress; 3) T cells in target organs: from the spleen to vessels and kidney. The results of this strategy will unravel important new mechanistic insights in HTN and particularly will have significant implications for understanding how immunity and - autonomic nervous system cooperate to rise BP. Based on the emerging view of HTN as an “immune disorder”, we believe that this strategy will add decisive knowledge in this field that could pave the way for developing immunotherapies for the treatment - of resistant HTN. - - 2022-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Italy - - - SymPAtHY - - - ERC-2017-STG - - - 759921 - - - - - UNIVERSIDAD POMPEU FABRA - UNIVERSIDAD POMPEU FABRA - - - EUR 1 488 506 - - - Resilience and Adaptation in Drylands. Identifying past water management practices for drought-resistant crops - - - EUR 1 488 506 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - RAINDROPS will investigate cultivation practices that support human resilience and adaptation in drylands, by developing an innovative and reliable methodology for the identification of water management practices from - archaeobotanical remains. Irrigation, river floods or permanent water sources are often deemed necessary for cultivation to be practised in drylands. However, there are modern examples that testify to the existence of successful rain-fed cultivation - systems, even in hyper-arid environments. Quantification of the extent of these practices in the past has the potential to dramatically change our understanding of human adaptation and agriculture. By establishing a protocol for the accurate - identification of rain-fed cultivation, RAINDROPS will pave the way for the investigation of this practice in the past. Highly controlled data on phytolith ratios, and carbon, oxygen and silicon isotopes from macro- and micro-remains from - experimental fields of finger millet [Eleusine coracana (L.) Gaertn.] and sorghum [Sorghum bicolor (L.) Moench] will be validated with ethnographic evidence before being applied to selected key archaeological case studies. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Spain - - - RAINDROPS - - - ERC-2017-STG - - - 759800 - - - - - "NATIONAL CENTER FOR SCIENTIFIC RESEARCH ""DEMOKRITOS""" - ISTITUTO NAZIONALE DI GEOFISICA E VULCANOLOGIA - THE UNIVERSITY OF EDINBURGH - CENTRE EUROPEEN DE RECHERCHE ET DE FORMATION AVANCEE EN CALCUL SCIENTIFIQUE - THE UNIVERSITY OF LIVERPOOL - KONINKLIJK NEDERLANDS METEOROLOGISCH INSTITUUT-KNMI - ETHNIKO DIKTYO EREVNAS TECHNOLOGIAS AE - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - ATHINA-EREVNITIKO KENTRO KAINOTOMIAS STIS TECHNOLOGIES TIS PLIROFOFORIAS, TON EPIKOLNONION KAI TIS GNOSIS - - - EUR 2 957 500 - - - Delivering Agile Research Excellence on European e-Infrastructures - - - EUR 2 957 500 - - - Greece - Italy - United Kingdom - France - United Kingdom - Netherlands - Greece - Germany - Greece - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - - DARE (Delivering Agile Research Excellence on European e-Infrastructures) aims to provide scientific communities with a unifying hyper-platform and development context to allow for user-friendly and reproducible carrying out - of huge data-driven experiments, and rapid prototyping. DARE specifically addresses the requirements of innovating teams of research developers and scientists, who work on the intersection of software engineering and scientific domains, and on data, - complexity and computing extremes. - - 2020-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.3."> - - - EINFRA-21-2017 - Platform-driven e-infrastructure innovation - - - RIA - Research and Innovation action - - - Greece - - - DARE - - - H2020-EINFRA-2017 - - - 777413 - - - - - THE MANCHESTER METROPOLITAN UNIVERSITY - INSTITUT DRUSTVENIH ZNANOSTI IVO PILAR - TALLINN UNIVERSITY - UNIVERSITAET BREMEN - AGENCIA CATALANA DE LA JUVENTUD - PANTEIO PANEPISTIMIO KOINONIKON KAIPOLITIKON EPISTIMON - DEBRECENI EGYETEM - UNIVERSITY OF ESSEX - UNIVERZITA SV CYRILA A METODA V TRNAVE - DAUGAVPILS UNIVERSITATE - INSTITUTO UNIVERSITARIO DE LISBOA - JYVASKYLAN YLIOPISTO - ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA - UNIVERSITY COLLEGE LONDON - KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW - EUROPEAN SOCIAL SURVEY EUROPEAN RESEARCH INFRASTRUCTURE CONSORTIUM - - - EUR 2 048 880 - - - European Cohort Development Project - - - EUR 2 048 880 - - - United Kingdom - Croatia - Estonia - Germany - Spain - Greece - Hungary - United Kingdom - Slovakia - Latvia - Portugal - Finland - Italy - United Kingdom - Netherlands - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - - The European Cohort Development Project (ECDP) is a Design Study which will create the specification and business case for a European Research Infrastructure that will provide, over the next 25 years, comparative longitudinal - survey data on child and young adult well-being. The infrastructure developed by ECDP will subsequently coordinate the first Europe wide cohort survey, which we name EuroCohort. - - - 2019-06-30, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-01-2017 - Design Studies - - - RIA - Research and Innovation action - - - United Kingdom - - - ECDP - - - H2020-INFRADEV-2017-1 - - - 777449 - - - - - BIRMINGHAM CITY UNIVERSITY - SINGULARLOGIC ROMANIA COMPUTER APPLICATIONS SRL - - - EUR 761 644,44 - - - Internet of Thing for Smart Water Innovative Networks - - - EUR 761 644,44 - - - United Kingdom - Romania - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The IoT4Win will establish a European Industrial Doctorates (EID) training program and extend the traditional academic research training setting, equipping researchers with right combination of research-related and - transferable competences, joint research training programme combines an interdisciplinary expertise of European research group, industry partners and user organisations, bring together all required knowledge, skills, and stakeholders to offer a - comprehensive set of transferable skills and a training programme on ICT, data science and water engineering, including industry practice and longer-term benefit in further industrial partner collaborations and further knowledge transfer. IoT4Win - will respond to well defined and interdisciplinary scientific questions and challenges on IoTs for Smart Water Network (SWN) technological area cooperating to recruit 3 ESRs to undertake research in the context of a joint research training on - concepts and methodologies of IoT enabled SWN towards the PhD. IoT4Win designs 3 individual and personalised research projects covering the core SWN research areas, i.e. smart sensing and trusted communication within energy limited heterogeneous - devices in IoT enabled urban water environment; dynamic sensor web and interoperable open platform with Integrated Knowledge Management for smart water networks; data security and intelligence in IoT enabled SWN. The interdisciplinary collaborations - and cross industrial interactions between ICT and water sector, will expose researchers to the academic, non-academic sectors. By combining three projects, an interoperable, secure and intelligent underlying technology leading to an open platform for - IoT enabled SWN applications will be developed. This platform will then be applied to and evaluated in the real water scenarios with our end user industrial partner, leading to a specialised technology platform for SWN and a best-practice smart water - network demonstrator. - - 2022-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-EID - European Industrial Doctorates - - - United Kingdom - - - IoT4Win - - - H2020-MSCA-ITN-2017 - - - 765921 - - - - - INSTITUTO DE CIENCIAS SOCIAIS - INSTITUTO DE CIENCIAS SOCIAIS - - - EUR 1 467 727 - - - Rescuing seeds’ heritage: engaging in a new framework of agriculture and innovation since the 18th century - - - EUR 1 467 727 - - - Portugal - Portugal - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Humanity is facing a huge challenge: how to feed a growing population in a sustainable way? Scientists from different fields are looking for answers and ReSEED aims to assist such endeavours. Solutions depend on one key issue: - seeds. We can have appropriate soil, climate or technologies, however without proper seeds it is impossible to guarantee food production. As historiography has given little attention to the role of seed varieties, there are many gaps in scientific - knowledge. I argue that long-term historical analysis is critical to provide the best answers to current questions. ReSEED examines the changing connections between seeds, environment and human action, the triangle that has always underpinned - agriculture, since the 18th century. The main objectives are as follows. 1) To map geographical changes in local crop distribution, paying attention to the new seeds made available by Columbian Exchange. 2) To outline which were the social networks - supporting the circulation and cultivation of edible seed varieties, and at later date, checking how they articulated with state services. 3) To identify human factors that contribute to reducing, increasing, maintaining or restoring regional - agro-biodiversity. 4) To assess the impacts of national and international decisions on local management of the triangle, mainly on farmers’ innovation. 5) To re-examine the long-term dynamics behind various European agricultural modernization - itineraries. Based on innovative interdisciplinary and transdisciplinary methodologies, I build robust empirical research on the case of Iberian Peninsula in connection to empires, which allows thorough comparisons with other regions in Europe and - beyond. ReSEED promotes strategies for win-win environmental/society outcomes, linking edible seeds to places and to innovations needed for food production. This is crucial to better understand how historical experiences can contribute to create - solutions that ensure sustainable futures. - - 2023-05-31, Grant Agreement signed - - - 2018-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Portugal - - - ReSEED - - - ERC-2017-STG - - - 760090 - - - - - EUROPEAN MOLECULAR BIOLOGY LABORATORY - EUROPEAN MOLECULAR BIOLOGY LABORATORY - - - EUR 1 228 125 - - - In situ Structural Analysis of Molecular Crowding and Phase Separation - - - EUR 1 228 125 - - - Germany - Germany - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - This proposal brings together two fields in biology, namely the emerging field of phase-separated assemblies in cell biology and state-of-the-art cellular cryo-electron tomography, to advance our understanding on a - fundamental, yet illusive, question: the molecular organization of the cytoplasm. - - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - 3DCellPhase- - - - ERC-2017-STG - - - 760067 - - - - - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - - - EUR 1 313 103 - - - Firm Growth and Market Power in the Global Economy - - - EUR 1 313 103 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - According to the European Commission, to design effective policies for ensuring a “more dynamic, innovative and competitive” economy, it is essential to understand the decision-making process of firms as they differ a lot in - terms of their capacities and policy responses (EC 2007). The objective of my future research is to provide such an analysis. BIGlobal will examine the sources of firm growth and market power to provide new insights into welfare and policy in a - globalized world. - - 2022-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - BIGlobal - - - ERC-2017-STG - - - 760037 - - - - - CARDIFF UNIVERSITY - CARDIFF UNIVERSITY - - - EUR 1 383 920 - - - Data Justice: Understanding datafication in relation to social justice - - - EUR 1 383 920 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project explores the meaning of social justice in an age of datafication. It is premised on two significant developments: 1) the shift to a focus on the collection and processing of massive amounts of data across social - life and 2) the increasing concern with the societal implications of such processes. Whilst initial concern with the technical ability to ‘datafy’ and collect information on ever-more social activity focused on surveillance and privacy, increasing - emphasis is being placed on the fact that data processes are not ‘flat’ and do not implicate everyone in the same way, but, rather, are part of a system of ‘social sorting’, creating new categories of citizens, and premised on an emerging order of - ‘have’ and ‘have nots’ between data profilers and data subjects. In such a context, questions of social justice and datafication require detailed study. This project frames this research agenda around the notion of ‘data justice’. It will provide a - European framework of study and take a holistic approach by situating research on data processes in the context of a) the concrete experiences and practices of particular communities; b) technological analyses of data sources, algorithmic process and - data output; c) policy frameworks that relate to the interplay between digital rights and social and economic rights; and d) conceptual engagement with new social stratifications emerging with datafication. The project is ground-breaking in five - different respects: i) it conceptually advances the meaning of social justice in a datafied society; ii) it shifts and challenges dominant understandings of data by highlighting its relation to social and economic rights; iii) it addresses an - uncharted but rapidly growing response to datafication in civil society; iv) it breaks down disciplinary boundaries in understandings of technology, power, politics and social change; and v) it pursues a combination of engaged research and - socio-technical modes of investigation. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - DATAJUSTICE - - - ERC-2017-STG - - - 759903 - - - - - CONSIGLIO NAZIONALE DELLE RICERCHE - CONSIGLIO NAZIONALE DELLE RICERCHE - - - EUR 1 050 000 - - - SENSING CELL-CELL INTERACTION HETEROGENEITY IN 3D TUMOR MODELS:TOWARDS PRECISION MEDICINE - - - EUR 1 050 000 - - - Italy - Italy - - - Research Organisations - Research Organisations - - This project aims to investigate the role of potassium (K+), protons (H+) and oxygen (O2) gradients in the extracellular space of tumour cells grown in 3D cultures by using a combination of imaging, cell biology and in silico - analyses. By embedding ratiometric fluorescent particle-based sensors within 3D scaffolds, the changes in target analyte concentrations can be monitored and used to study the interactions between tumour cells and stromal cells in 3D - tumoroids/scaffolds and to monitor response of the cells to drug treatments. I first demonstrated successful fabrication of barcoded capsules for multiplex sensing of H+, K+, and Na+ ions. Next, I demonstrated the use of pH-sensing capsules as valid - real time optical reporter tools to sense and monitor intracellular acidification in living cells. Thus, I can fabricate capsule sensors for investigating the role of key analytes that are involved in regulation of crucial physiological mechanisms. - In addition, I successfully integrated pH-sensing capsules within 3D nanofibrous matrices and demonstrated their operation under pH switches. INTERCELLMED will engineer 3D scaffolds that do not only sense extracellular pH but are also able to sense - K+ and O2 changes. To this aim, a novel set of anisotropic analyte-sensitive ratiometric capsules will be developed and applied for generating robust and flexible capsules-embedded sensing scaffolds. To validate the functions of the 3D sensing - platform, cocoltures of tumour cells and stromal cells will be grown and their interaction and response to drug treatments will be studied by mapping the K+/H+/O2 gradients in and around the cell aggregates. Finally, the 3D sensing platform will be - adapted for growing tumour tissue-derived cells that will be tested ex-vivo with anticancer dugs. Specific mathematical models of cellular interactions will be developed to represent the biological processes occurring within the 3D sensing platform. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Italy - - - INTERCELLMED - - - ERC-2017-STG - - - 759959 - - - - - UNIVERSITY OF GLASGOW - UNIVERSITY OF GLASGOW - - - EUR 1 239 435 - - - Categorified Donaldson-Thomas Theory - - - EUR 1 239 435 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - According to string theory, coherent sheaves on three-dimensional Calabi-Yau spaces encode fundamental properties of the universe. On the other hand, they have a purely mathematical definition. We will develop and use the new - field of categorified Donaldson-Thomas (DT) theory, which counts these objects. Via the powerful perspective of noncommutative algebraic geometry, this theory has found application in recent years in a wide variety of contexts, far from classical - algebraic geometry. - - 2022-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - CatDT - - - ERC-2017-STG - - - 759967 - - - - - TECHNISCHE UNIVERSITEIT DELFT - TECHNISCHE UNIVERSITEIT DELFT - - - EUR 2 000 000 - - - Selective Conversion of Water and CO2 Using Interfacial Electrochemical Engineering - - - EUR 2 000 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The recycling of CO2 will play an important role in mitigating the energy and environmental problems that our future societies will no doubt face. Electrochemistry is a powerful technology that can make use of renewable - electricity from solar and wind to power the transformation of CO2 and water to valuable chemicals and fuels. However, the electrochemical conversion of CO2 is not ready for large-scale deployment due to the poor activity, selectivity, and stability - of the current catalysts used. The only way to be able to achieve better understanding of this complicated system is through careful characterization of the catalyst/electrolyte interface during electrochemical measurements, as well as the - development of new theoretical models that include the effects of the electrolyte. - - 2022-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - WU TANG - - - ERC-2017-STG - - - 759743 - - - - - TECHNISCHE UNIVERSITEIT DELFT - TECHNISCHE UNIVERSITEIT DELFT - STICHTING VUMC - - - EUR 150 000 - - - An EEG calibration toolkit for monitoring rehabilitation of stroke patients. - - - EUR 150 000 - - - Netherlands - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - An EEG calibration toolkit for monitoring rehabilitation of stroke patients - - 2019-06-30, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Netherlands - - - MRI4DEEG - - - ERC-2017-PoC - - - 767235 - - - - - TECHNISCHE UNIVERSITEIT EINDHOVEN - Philips GmbH - - - EUR 766 122,84 - - - Open Ground Truth Training Network : Magnetic resonance image simulationfor training and validation of image analysis algorithms - - - EUR 766 122,84 - - - Netherlands - Germany - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - This action aims to optimally prepare three young researchers for the evolving medical imaging world by offering a unique set of targeted interdisciplinary training and research assignments in the areas of anatomy, pathology, - imaging techniques, quantitative image analysis and segmentation, Magnetic Resonance (MR) physics and MR image simulation. - - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-EID - European Industrial Doctorates - - - Netherlands - - - OpenGTN - - - H2020-MSCA-ITN-2017 - - - 764465 - - - - - UNIVERSIDADE NOVA DE LISBOA - UNIVERSIDADE NOVA DE LISBOA - INSTITUTO DE BIOLOGIA EXPERIMENTAL E TECNOLOGICA - - - EUR 1 697 493 - - - Metabolic and Timed Control of Stem Cell Fate in the Developing Animal - - - EUR 1 697 493 - - - Portugal - Portugal - Portugal - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - Stem cell (SC) proliferation during development requires tight spatial and temporal regulation to ensure correct cell number and right cell types are formed at the proper positions. Currently very little is known about how SCs - are regulated during development. Specifically, it is unclear how SC waves of proliferation are regulated and how the fate of their progeny changes during development. In addition, it has recently become evident that metabolism provides additional - complexity in cell fate regulation, highlighting the need for integrating metabolic information across physiological levels. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Portugal - - - StemCellHabitat - - - ERC-2017-STG - - - 759853 - - - - - UNIVERSITATEA TEHNICA CLUJ-NAPOCA - SIEMENS INDUSTRY SOFTWARE NV - Brose Fahrzeugteile GmbH & Co. Kommanditgesellschaft, Wurzburg - UNIVERSITE LIBRE DE BRUXELLES - ICPE SA - - - EUR 1 409 046,14 - - - European Industrial Doctorate on Next Generation for sustaINable auTomotive ElectRical ACtuaTion - - - EUR 1 409 046,14 - - - Romania - Belgium - Germany - Belgium - Romania - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The trend for more electrified automotive applications (MEAA) asks for a new generation of automotive electrical actuation systems, allowing for a more efficient and environmentally friendly mobility and enhancing the driving - experience, making it safer, more comfortable and sustainable. - - - 2021-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-EID - European Industrial Doctorates - - - Romania - - - INTERACT - - - H2020-MSCA-ITN-2017 - - - 766180 - - - - - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - - - EUR 149 645 - - - MAmmary chemoresistant Tumor deAth by Directed cell ORientation - - - EUR 149 645 - - - France - France - - - Research Organisations - Research Organisations - - Breast cancer is the most common cancer in women worldwide, with nearly 1.7 million new cases diagnosed in 2012. Fortunately, the availability of diagnosis tools to detect mammary neoplastic tissues, as well as transcriptomic - biomarkers helping for prognosis, and the diversity of treatment options for primary tumors allows a 90% 5-year survival rate. However the metastatic grade of breast cancer is still not curable. - - 2019-05-31, Grant Agreement signed - - - 2018-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - France - - - MATADOR - - - ERC-2017-PoC - - - 780458 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 149 852 - - - Innovative testing of microRNA from liquid biopsies using bistable molecular circuits - - - EUR 149 852 - - - France - France - - - Research Organisations - Research Organisations - - We are designing molecular networks - based on DNA programing- to detect extremely dilute molecular signals and robustly separate them from background noise. This could have relevant applications in the field of molecular - diagnostics, in particular in the area of ultra-sensitive testing of nucleic acids from liquid biopsy for example for the detection of circulating microRNA. MicroRNA are difficult targets for standard ultra sensitive techniques such as quantitative - PCR, but, because of their presence in the blood stream, they also represent an emerging class of important biomarkers for a wide range of diseases, including cancer. - - - 2019-05-31, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - France - - - DeepMiR - - - ERC-2017-PoC - - - 780519 - - - - - DEUTSCHES ZENTRUM FUR NEURODEGENERATIVE ERKRANKUNGEN EV - DEUTSCHES ZENTRUM FUR NEURODEGENERATIVE ERKRANKUNGEN EV - - - EUR 148 403 - - - Redefining Virtual Reality Therapy for Anxiety Disorders - - - EUR 148 403 - - - Germany - Germany - - - Research Organisations - Research Organisations - - Social anxiety disorder (SAD) – the most common type of anxiety disorders – has severe emotional, financial and social consequences for patients, their families and their social network. Affecting about 7% of Europeans at some - point in their life, SAD produces substantial societal cost due to long lasting treatments and extensive periods of reduced working capacity. To address this important problem, the project will establish an innovative system for treating SAD by - exploiting the proven therapeutic potential of advanced Virtual Reality (VR) technology. - - 2019-05-31, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Germany - - - NEOMENTO - - - ERC-2017-PoC - - - 780453 - - - - - UNIVERSITA DEGLI STUDI DI TRENTO - UNIVERSITA DEGLI STUDI DI TRENTO - FONDAZIONE TOSCANA LIFE SCIENCES - - - EUR 150 000 - - - Engineered bacterial Outer Membrane Vesicles (OMVs) for colorectal cancer immunotherapy - - - EUR 150 000 - - - Italy - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - This proposal originates from recent results obtained in the course of the Advanced ERC Project “OMVac”, the scope of which is to exploit the unique adjuvanticity properties of bacterial Outer Membrane Vesicles (OMVs) for - developing innovative vaccines against infectious diseases and cancer. In particular, Synthetic Biology was applied to engineer OMVs with FAT1, a tumour associated antigen expressed in most primary and metastatic colorectal cancers (CRC). Using - cancer models in immunocompetent mice, immunization with FAT1-decorated OMVs inhibited subcutaneous growth of FAT1-positive CT26 cancer cells and protection correlated with an increase in tumour infiltration of CD4+/CD8+ T cells and concomitant - decrease of Treg and MDSCs. These promising results prompted the submission of the present proposal which has as main objectives: 1) the demonstration that FAT1-OMV immunization can synergise with the protective activity of checkpoint inhibitors, and - 2) the development of a scalable FAT1-OMV production and purification process which could allow testing FAT1-OMV/checkpoint inhibitor combination in the clinical setting. - - 2019-06-30, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Italy - - - OMVCRC - - - ERC-2017-PoC - - - 780417 - - - - - RIJKSUNIVERSITEIT GRONINGEN - RIJKSUNIVERSITEIT GRONINGEN - - - EUR 1 480 708 - - - The Rules of Interpretation of Customary International Law - - - EUR 1 480 708 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This ERC proposal revolves around the rules of interpretation of customary international law (CIL). CIL along with treaties are the rules most often used in international law. However, whereas rules of interpretation of - treaties have been enshrined in Articles 31-33 of the Vienna Convention on the Law of Treaties (VCLT), the rules of interpretation of CIL have not been the subject of critical study. This gap becomes even more pronounced if we consider that - interpretation plays a key role in every judicial case, and that one of the basic markers of effectiveness of any legal system is its predictability. By not knowing the rules that govern the interpretation of CIL, we end up playing a ‘game’ the rules - of which are unknown, and by consequence predictability is far from guaranteed. - - 2023-04-30, Grant Agreement signed - - - 2018-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - TRICI-Law - - - ERC-2017-STG - - - 759728 - - - - - UPPSALA UNIVERSITET - UPPSALA UNIVERSITET - - - EUR 1 500 000 - - - The African Neolithic: A genetic perspective - - - EUR 1 500 000 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The spread of farming practices in various parts of the world had a marked influence on how humans live today and how we are distributed around the globe. Around 10,000 years ago, warmer conditions lead to population - increases, coinciding with the invention of farming in several places around the world. Archaeological evidence attest to the spread of these practices to neighboring regions. In many cases this lead to whole continents being converted from - hunter-gatherer to farming societies. It is however difficult to see from archaeological records if only the farming culture spread to other places or whether the farming people themselves migrated. Investigating patterns of genetic variation for - farming populations and for remaining hunter-gatherer groups can help to resolve questions on population movements co-occurring with the spread of farming practices. It can further shed light on the routes of migration and dates when migrants - arrived. - - 2022-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Sweden - - - AfricanNeo - - - ERC-2017-STG - - - 759933 - - - - - UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II. - UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II. - - - EUR 1 481 813 - - - Disasters, Communication and Politics in South-Western Europe: the Making of Emergency Response Policies in the Early Modern Age - - - EUR 1 481 813 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The connections between the circulation of news of extreme events, the making of influential narratives of collective traumas and the development of emergency response policies lie at the heart of this research proposal, which - focuses on four Southern European areas: Catalonia, Naples, Sicily and Valencia, from the 16th to the 18th century. How did accounts and individual memories of extreme events amount to authoritative interpretations? In which ways, and to what extent, - did the latter orient collective behaviours and the recovery process, in both the short and the long term? - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Italy - - - DISCOMPOSE - - - ERC-2017-STG - - - 759829 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 770 375 - - - Regulatory genomics during Drosophila embryogenesis: dissecting enhancer-promoter interactions - - - EUR 1 770 375 - - - France - France - - - Research Organisations - Research Organisations - - In eukaryotes, the complex regulation of temporal- and tissue-specific gene expression is controlled by the binding of transcription factors to enhancers, which in turn interact with the promoter of their target gene(s) via - the formation of a chromatin loop. Despite their importance, the properties governing enhancer function and enhancer-promoter loops in the context of the three-dimensional organisation of the genome are still poorly understood. - - 2023-04-30, Grant Agreement signed - - - 2018-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - Enhancer3D - - - ERC-2017-STG - - - 759708 - - - - - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - - - EUR 1 498 187,50 - - - Perovskite Nanocrystal-Nanoreactors for Enhanced Light Emission - - - EUR 1 498 187,50 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The unprecedented advancement of halide perovskite photovoltaics and light-emission applications has far outpaced the basic scientific research necessary to understand this fascinating yet perplexing material and to optimize - material quality and device integration. Additionally, the intricate nature of the perovskite is susceptible to degradation from environmental stress, such as moisture and heat, currently deterring commercialization. - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - PINNACLE - - - ERC-2017-STG - - - 759744 - - - - - FONDATION POUR L INSTITUT DE HAUTES ETUDES INTERNATIONALES ET DU DEVELOPPEMENT - FONDATION POUR L INSTITUT DE HAUTES ETUDES INTERNATIONALES ET DU DEVELOPPEMENT - - - EUR 1 500 000 - - - Returning to a Better Place: The (Re)assessment of the ‘Good Life’ in Times of Crisis - - - EUR 1 500 000 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - What makes for a valuable and good life is a question that many people in the contemporary world ask themselves, yet it is one that social science research has seldom addressed. Only recently have scholars started undertaking - inductive comparative research on different notions of the ‘good life’, highlighting socio-cultural variations and calling for a better understanding of the different imaginaries, aspirations and values that guide people in their quest for better - living conditions. Research is still lacking, however, on how people themselves evaluate, compare, and put into perspective different visions of good living and their socio-cultural anchorage. This project addresses such questions from an - anthropological perspective, proposing an innovative study of how ideals of the good life are articulated, (re)assessed, and related to specific places and contexts as a result of the experience of crisis and migration. The case studies chosen to - operationalize these lines of enquiry focus on the phenomenon of return migration, and consist in an analysis of the imaginaries and experience of return by Ecuadorian and Cuban men and women who migrated to Spain, are dissatisfied with their life - there, and envisage/carry out the project of going back to their countries of origin (Ecuador and Cuba respectively). The project’s ambition is to bring together and contribute to three main scholarly areas of enquiry: 1) the study of morality, - ethics and what counts as ‘good life’, 2) the study of the field of economic practice, its definition, value regimes, and ‘crises’, and 3) the study of migratory aspirations, projects, and trajectories. A multi-sited endeavour, the research is - designed in three subprojects carried out in Spain (PhD student), Ecuador (Post-Doc), and Cuba (PI), in which ethnographic methods will be used to provide the first empirically grounded study of the links between notions and experiences of crisis, - return migration, and the (re)assessment of good living. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Switzerland - - - BETLIV - - - ERC-2017-STG - - - 759649 - - - - - DEUTSCHES KREBSFORSCHUNGSZENTRUM - DEUTSCHES KREBSFORSCHUNGSZENTRUM - - - EUR 1 499 375 - - - Exploring cell interactions in the tumor microenvironment with dual ribosome profiling - - - EUR 1 499 375 - - - Germany - Germany - - - Research Organisations - Research Organisations - - Cancers develop in very heterogeneous tissue environments. They depend on the tumor microenvironment (TME) for sustained growth, metastasis, and therapy resistance. Stromal cells are genetically stable and they have less - likelihood to develop resistance than cancer cells. Therefore, targeting the TME represents an attractive approach for treating cancer. In order to develop new therapeutic strategies to reprogram the TME and inhibit tumor growth and resistance, it is - essential to understand in detail the molecular mechanisms of the interactions between cancer and stromal cell populations. However, current methods to study these interactions require complete dissociation of the tumor, exposing the cells to severe - stress and affecting dramatically gene expression patterns. Here, I propose to use Dual Ribosome Profiling (DualRP), a system that I recently developed, to study cell interactions in the TME. DualRP is an approach that allows not only simultaneous - analysis of gene expression in two interacting cell populations in vivo, but also is able to uncover metabolic limitations in tumors. I aim to apply DualRP to mouse xenograft models where cancer cells interact with non-transformed fibroblasts and - I’ll explore the combined response of both populations to cancer therapy. Moreover, I’ll utilize mouse genetic models tailored for DualRP to study cancer cell and macrophages/endothelial cells interactions. I will employ a combination of mouse - genetic models, biochemical tools, deep sequencing, and bioinformatics. These studies will provide insight into how gene expression and metabolic programs define the interaction between cancer and stromal cells to promote tumor growth and metastasis, - identify potential targets for therapeutic intervention, and provide maps of cell interactions in vivo. Therefore, this research has the potential to significantly advance our understanding of the molecular and metabolic mechanisms underlying the - complex cell interactions in the TME. - - 2023-04-30, Grant Agreement signed - - - 2018-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - DualRP - - - ERC-2017-STG - - - 759579 - - - - - UNIVERSITAETSKLINIKUM HEIDELBERG - UNIVERSITAETSKLINIKUM HEIDELBERG - - - EUR 1 500 000 - - - Dry season P. falciparum reservoir - - - EUR 1 500 000 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The mosquito-borne Plasmodium falciparum parasite is responsible for over 200 million malaria cases and nearly half a million deaths each year among African children. Dependent on Anopheles mosquito for transmission, the - parasite faces a challenge during the dry season in the regions where rain seasonality limits vector availability for several months. While malaria cases are restricted to the wet season, clinically silent P. falciparum infections can persist through - the dry season and are an important reservoir for transmission. Our preliminary data provides unequivocal evidence that P. falciparum modulates its transcription during the dry season, while the host immune response seems to be minimally affected, - suggesting that the parasite has the ability to adapt to a vector-free environment for long periods of time. Understanding the mechanisms which allow the parasite to remain undetectable in absence of mosquito vector, and to restart transmission in - the ensuing rainy season will reveal complex interactions between P. falciparum and its host. To that end I propose to: (i) Identify the Plasmodium signalling pathway(s) and metabolic profile associated with long-term maintenance of low parasitaemias - during the dry season, (ii) Determine which PfEMP1 are expressed by parasites during the dry season and how effectively they are detected by the immune system, and (iii) Investigate the kinetics of P. falciparum gametocytogenesis, its ability to - transmit during the dry season, and uncover sensing molecules and mechanisms of the disappearance and return of the mosquito vector Undoubtedly, results arising from the present multidisciplinary proposal will provide novel insights into the cell - biology of dry season P. falciparum parasites, will increase our understanding of their interactions with their hosts and environment. Furthermore, it may benefit the international development agenda goals to design public health strategies to fight - malaria. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - DrySeasonPf - - - ERC-2017-STG - - - 759534 - - - - - THE UNIVERSITY OF NOTTINGHAM - RISC SOFTWARE GMBH - UNIVERSIDADE DO PORTO - AIRBUS DEFENCE AND SPACE GMBH - - - EUR 1 266 011,28 - - - European industrial doctorate for efficient multidisciplinary design Optimization ofMultifunctional Aerospace Composite Structures - - - EUR 1 266 011,28 - - - United Kingdom - Austria - Portugal - Germany - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Modern aeronautical structures are increasingly made of composite materials due to their well-known benefits. Optimizing the design of aerospace composites vis-à-vis the entire range of operational constraints (i.e. - reliability, stability, strength, weight, noise, manufacturability and cost) to which the aircraft structures are subject, results in a particularly challenging task for the structural designer. Despite the volume of recent work dedicated to new - Multidisciplinary Design Optimization (MDO) models and techniques, the ‘No free lunch theorem in optimisation’ is constantly confirmed. - - 2022-04-30, Grant Agreement signed - - - 2018-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-EID - European Industrial Doctorates - - - United Kingdom - - - OptiMACS - - - H2020-MSCA-ITN-2017 - - - 764650 - - - - - ALBERT-LUDWIGS-UNIVERSITAET FREIBURG - ALBERT-LUDWIGS-UNIVERSITAET FREIBURG - - - EUR 1 488 750 - - - Supercapacitive Polymer Electrodes for Directing Epithelial Repair - - - EUR 1 488 750 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In this project we develop a new approach, using the conducting polymer poly (3,4-ethylene dioxythiophene) (PEDOT) to apply electrical fields (EFs) for guidance of cells. EFs are recognised as important guidance cues in the - development and life cycle of human tissues. However, better tools are urgently needed to support experiments and applications. By developing supercapacitive PEDOT electrodes, able to support an ionic flow over extended time frames, we here target - the most widely studied clinical application for EF stimulation, accelerated wound healing. Our technology facilitates the transfer from petri dish to device by offering an alternative driving process to metals. In addition, we establish a strategy - where electrodes can be recharged in situ, by using intermediate periods of current flow in the reverse direction and below the threshold for triggering a biological response. Ionic flow driven by PEDOT electrodes can, in contrast to metals, be - reversed with any small ion present in the electrolyte. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - SPEEDER - - - ERC-2017-STG - - - 759655 - - - - - UNIVERSITEIT VAN AMSTERDAM - UNIVERSITEIT VAN AMSTERDAM - - - EUR 1 499 631 - - - The Disrupted Society: mapping the societal effects of blockchain technology diffusion - - - EUR 1 499 631 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Recent advances in cryptography yielded the blockchain technology, which enables a radically new and decentralized method to maintain authoritative records, without the need of trusted intermediaries. Bitcoin, a cryptocurrency - blockchain application has already demonstrated that it is possible to operate a purely cryptography-based, global, distributed, decentralized, anonymous financial network, independent from central and commercial banks, regulators and the state. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - BLOCKCHAINSOCIETY - - - ERC-2017-STG - - - 759681 - - - - - VYSOKE UCENI TECHNICKE V BRNE - VYSOKE UCENI TECHNICKE V BRNE - - - EUR 1 377 495 - - - Towards the Understanding a Metal-Tumour-Metabolism - - - EUR 1 377 495 - - - Czech Republic - Czech Republic - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - A tumour cell uses both genetic and protein weapons in its development. Gaining a greater understanding of these lethal mechanisms is a key step towards developing novel and more effective treatments. Because the metal ion - metabolism of a tumour cell is not fully understood, we will address the challenge of explaining the mechanisms of how a tumour cell copes both with essential metal ions and platinum based drugs. The metal-based mechanisms help a tumour to grow on - one side and to protect itself against commonly used metal-based drugs. On the other side, the exact description of these mechanisms, which are being associated with multi-drug resistance occurrence and failure of a treatment, still remains unclear. - We will reveal the mechanism of the as yet not understood biochemical and molecularly-biological relationships and correlations between metal ions and proteins in a tumour development revealing the way how to suppress the growth and development of a - tumour and to markedly enhance the effectiveness of a treatment. - - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Czech Republic - - - ToMeTuM - - - ERC-2017-STG - - - 759585 - - - - - FORSCHUNGSINSTITUT FUR MOLEKULARE PATHOLOGIE GESELLSCHAFT MBH - FORSCHUNGSINSTITUT FUR MOLEKULARE PATHOLOGIE GESELLSCHAFT MBH - - - EUR 1 500 000 - - - Rational combination therapies for metastatic cancer - - - EUR 1 500 000 - - - Austria - Austria - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Targeted therapy (TT) is frequently used to treat metastatic cancer. Although TT can achieve effective tumor control for several months, durable treatment responses are rare, due to emergence of aggressive, drug-resistant - clones (RCs) with high metastatic competence. Tumor heterogeneity and plasticity result in multifaceted resistance mechanisms and targeting RCs poses a daunting challenge. - - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Austria - - - CombaTCancer - - - ERC-2017-STG - - - 759590 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSITAET LEIPZIG - THE UNIVERSITY OF BIRMINGHAM - - - EUR 1 497 168 - - - Hausa and Kanuri languages as archive for the history of Sahara and Sahel in 18th and 19th century - - - EUR 1 497 168 - - - France - France - Germany - United Kingdom - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The eighteenth and nineteenth century history of the central Sahara and Sahel has primarily been written using European or jihadist Arabic sources. This has led to an overwhelming emphasis on religion, politics, and geography - as core themes that shaped social and cultural dynamics in this region. By focusing on sources in African languages—until now largely forgotten by historians—the project LANGARCHIV aims to enrich and expand this narrative. Hausa and Kanuri material - collected by Germanophone, British, and French scholars for linguistic study between 1772 and 1913 in West and North Africa, England, and Brazil cries out for collaboration between historians, linguists, and anthropologists. This rich body of primary - sources remains under-studied, having been rejected as colonial even though the majority were collected before colonial occupation. A general reconsideration of this material will enable a major shift in our understanding, toward a ‘history from - below’ that will make it possible to explore the history of Sahelian societies through the stories that Sahelians told about themselves. Serving as linguae francae, in the eighteenth and nineteenth centuries Hausa and Kanuri were spoken from Tripoli - to Kano and Bahia, and today Hausa remains the most widely spoken language in West Africa, with 50 million speakers scattered over more than 6 countries LANGARCHIV will be the first project to explore materials in African languages as sources for - African history. Combining an epistemological analysis of European scientific interest in African languages with the will to write a social history that overcomes the jihadist bias, the project aims to bring about a paradigmatic shift in the history - of the central Sahara and Sahel. It will achieve this goal by revealing a rich body of primary sources and by developing an innovative analytical framework for using documents generated by early students of African languages and cultures as - historical sources. - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - LANGARCHIV - - - ERC-2017-STG - - - 759390 - - - - - LANCASTER UNIVERSITY - LANCASTER UNIVERSITY - - - EUR 1 493 605 - - - Hidden Hunger, Forgotten Food - - - EUR 1 493 605 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Food Security is a grand challenge of our time, but three factors inhibit our ability to meet global targets. First, interdisciplinary approaches incorporating ecological, social, and health sciences are fundamental, but - lacking. Second, a disproportionate focus on food quantity overlooks ‘hidden hunger’, or micronutrient deficiencies, which are implicated in over a million deaths annually. Third, small-scale fisheries (SSF) reach 100s of millions of people in the - developing world, hold potential for achieving food security, but remain ‘forgotten food’ in global discourse. Consequently, an interdisciplinary approach that tackles hidden hunger within SSF is a critical frontier for food security research. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - FAIRFISH - - - ERC-2017-STG - - - 759457 - - - - - THE UNIVERSITY OF BIRMINGHAM - THE UNIVERSITY OF BIRMINGHAM - - - EUR 1 466 014 - - - Spatio-Temporal Attention and Representation Tracking: the precise neural architecture of conscious object perception - - - EUR 1 466 014 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The ability to consciously recognise faces, objects, or sounds is crucial for adaptive behaviour and survival. Yet, how our conscious experience of the world emerges in our brain remains unknown. The overall aim of the START - programme is to fill an important gap in our understanding of consciousness by elucidating the neural underpinnings of conscious access. How does the brain select relevant information among distractors, and keep this information in mind? Why does our - ability to consciously recognise salient objects sometimes fail under pressure and exhibit variability across days and individuals? Current theories of conscious access thus far rely on EEG recordings or fMRI measurements, which in isolation offer - limited insights into the precise neural dynamics of conscious access. A further shortcoming of current models is their limited explanations for inter-trial and inter-individual variations in conscious access thresholds. START will tackle these - challenges using attentional blink tasks involving the perception and recollection of visual objects. First, it will precisely track where in the brain and when in time the representations critical for conscious access are established, by using a - novel approach which combines the strengths of EEG, fMRI, and Deep Convolutional Neuronal Networks. Second, START will reveal how activity patterns are amplified by the brain and encoded in working memory using multivariate pattern analyses of EEG - data and novel experimental designs. Finally, START will carefully model variability in task performance across trials and participants using a new approach of representational sampling. In summary, START will provide new insights on the precise - spatio-temporal dynamics of conscious access, the mechanisms governing it, and the idiosyncratic subtleties behind the meanderings of consciousness. This has deep implications for our understandings of brain health and disease, especially in clinical - cases where consciousness is impaired. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - START - - - ERC-2017-STG - - - 759432 - - - - - STICHTING KATHOLIEKE UNIVERSITEIT BRABANT - STICHTING KATHOLIEKE UNIVERSITEIT BRABANT - - - EUR 1 496 944 - - - Belief Systems Project - - - EUR 1 496 944 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Belief systems research is vital for understanding democratic politics, extremism, and political decision-making. What is the basic structure of belief systems? Clear answers to this fundamental question are not forthcoming. - This is due to flaws in the conceptualization of belief systems. The state-of-the-art treats a belief system as a theoretical latent variable that causes people’s responses on attitudes and values relevant to the belief system. This approach cannot - assess a belief system because it cannot assess the network of connections between the beliefs–attitudes and values–that make up the system; it collapses across them and the interrelationships are lost. - - - 2023-06-30, Grant Agreement signed - - - 2018-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - BSP - - - ERC-2017-STG - - - 759320 - - - - - UNIVERSITE JEAN MONNET SAINT-ETIENNE - UNIVERSITE JEAN MONNET SAINT-ETIENNE - - - EUR 1 060 250 - - - Micro-pyrites associated with organic material in ancient stromatolites: a new proxy attesting for their biogenicity - - - EUR 1 060 250 - - - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Identifying Archean fossil remains from the Earth’s early biosphere is ambitious and determining the biological origin and the associated metabolic pathways present in these fossils is one outstanding question in the bigger - quest of how life evolved on Earth. Stromatolites and Microbially Induced Sedimentary Structures (MISS) are considered as one of the earliest evidence of Life in Earth’s history, and can be found from the Archean to the present time. Stromatolites - are “attached laminated, sedimentary growth structure accretionary away from a point of initiation”, and their morphological comparison with actual structure prevail for assessing the microbial origin of ancient stromatolite in the geological record. - However, experimental studies have shown that abiotic precipitation can also form structures with a similar morphology. Therefore stable isotope proxies have been used to identify past microbial metabolisms even if abiotic processes can also produce - similar isotope composition. Therefore new biogenicity criteria are needed to be determined by studying modern and ancient stromatolites and by comparing them to abiotic experiment. Stromatolites and MISS contain submicrometer sulfides (pyrite) that - can have recorded large isotopic variations, interpreted as reflecting the influence of various microbial metabolisms like microbial sulfate reduction and iron respiration. STROMATA proposes to define new criteria based on actual stromatolite and to - test the earliest traces of life by studying in situ these nano-pyrites in various emblematic and well-characterized samples from the Archean. STROMATA will be the first far-reaching scientific in situ study of nano-pyrite in ancient (3.4 to 1.9 Ga) - and modern microbial mats and stromatolites and will compare the results with experimentally produced abiotic pyrite. Due to the small scale of the pyrite, STROMATA will develop an original in situ approach by combining state of art techniques, SIMS, - NanoSIMS, FEG-TEM, XANES. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - STROMATA - - - ERC-2017-STG - - - 759289 - - - - - HITS GGMBH - HITS GGMBH - - - EUR 1 499 485 - - - General Relativistic Moving-Mesh Simulations of Neutron-Star Mergers - - - EUR 1 499 485 - - - Germany - Germany - - - Research Organisations - Research Organisations - - In the arising era of gravitational-wave (GW) astronomy the demand for the next-generation of neutron-star (NS) merger models has never been so great. By developing the first relativistic moving-mesh simulations of NS mergers, - we will be able to reliably link observables of these spectacular events to fundamental questions of physics. Our approach will allow us to maximize the information that can be obtained from different GW oscillations of the postmerger remnant. In - this way we will demonstrate the scientific potential of future postmerger GW detections to unravel unknown properties of NSs and high-density matter. Based on our models we will work out the optimal GW data analysis strategy towards this goal. - - 2023-04-30, Grant Agreement signed - - - 2018-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - GreatMoves - - - ERC-2017-STG - - - 759253 - - - - - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - - - EUR 1 998 423 - - - Long-range coupling of hole spins on a silicon chip - - - EUR 1 998 423 - - - France - France - - - Research Organisations - Research Organisations - - With the miniaturization of electronic devices, the semiconductor industry has to deal with complex technical barriers and is forced to introduce novel and innovative concepts. The project proposal is exactly in line with this - new paradigm as it proposes to divert CMOS technology to explore a new path for quantum spintronics. Concretely the project aims at using spin-orbit interaction present in the valence band of silicon to drive ultra-fast and ultra-coherent hole spin - quantum bits (qubits). The proposal builds on the first demonstration by the principal investigator of a hole spin qubit electrically driven in silicon. - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - LONGSPIN - - - ERC-2017-STG - - - 759388 - - - - - DEUTSCHES HERZZENTRUM MUNCHEN - DEUTSCHES HERZZENTRUM MUNCHEN - - - EUR 1 477 680 - - - Stress as a modifier of atherosclerosis - Novel mechanistic insights and therapeutic avenues - - - - EUR 1 477 680 - - - Germany - Germany - - - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - Atherosclerosis and its complications such as acute coronary syndromes (myocardial infarction and unstable angina) are leading causes of death in the EU and worldwide. Mental stress is known to be a major trigger for the onset - of acute coronary syndromes, even in patients with state-of-the-art medical treatment. How acute mental stress rapidly drives plaque destabilization causing acute coronary syndromes is poorly understood and consequently specific treatment, although - urgently needed, is lacking. Mental stress is known to affect the immune system. Leukocytes, the effector cells of the immune system, are main instigators not only of plaque progression, but also of plaque destabilization. We hypothesize that acute - mental stress rapidly aggravates plaque inflammation, which renders plaques more vulnerable and prone to rupture. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - STRATO - - - ERC-2017-STG - - - 759272 - - - - - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - - - EUR 1 787 400 - - - Structural differences in mRNA translation machineries between eukaryotic pathogens and their mammalian hosts - - - EUR 1 787 400 - - - France - France - - - Research Organisations - Research Organisations - - mRNA translation consists on translating the genetic code to proteins by the ribosome that is universally conserved in all cells. However, its structure presents significant differences between bacteria and eukaryotes. Partly - because of these differences, the bacterial ribosome can be targeted specifically by a number of antibiotics without affecting the eukaryotic host cells. However, the conservation of the ribosome among eukaryotes complicates the search for specific - drugs against eukaryotic pathogens such as certain protozoa like plasmodium and kinetoplastids. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - transtryp - - - ERC-2017-STG - - - 759120 - - - - - THE UNIVERSITY OF BIRMINGHAM - THE UNIVERSITY OF BIRMINGHAM - - - EUR 1 498 982 - - - GLOBAL LITERARY THEORY - - - EUR 1 498 982 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Literary theory is often regarded as a twentieth century invention, with no precedents prior to modernity. This relegates older discourses on literature to the status of source material, pertaining to literature’s past, rather - than as springboards for literature’s future. While the self-understanding of literary theory’s modernity helped to bring about the discipline’s birth, and hence was innovative in its own time, at present it accounts for many gaps and limits within - its current structure, whereby European aesthetic categories remain normative and lesser-known geographies are marginalized within synthetic accounts of literary form. Even when the literatures studied are non-European, the literary theory used to - understand these texts often circulates within a restricted set of modern European traditions. - - 2023-04-30, Grant Agreement signed - - - 2018-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - GlobalLIT - - - ERC-2017-STG - - - 759346 - - - - - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - - - EUR 1 499 793,77 - - - Molecular mechanisms of interferon-induced antiviral restriction and signalling - - - EUR 1 499 793,77 - - - France - France - - - Research Organisations - Research Organisations - - Interferons (IFNs), which are signalling proteins produced by infected cells, are the first line of defence against viral infections. IFNs induce, in infected and neighbouring cells, the expression of hundreds of - IFN-stimulated genes (ISGs). The ISGs in turn induce in cells a potent antiviral state, capable of preventing replication of most viruses, including Human Immunodeficiency Virus type 1 (HIV-1) and influenza A virus (FLUAV). Identifying the antiviral - ISGs and understanding their mechanisms of action is therefore crucial to progress in the fight against viruses. - - - 2022-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - ANTIViR - - - ERC-2017-STG - - - 759226 - - - - - UNIVERSIDAD COMPLUTENSE DE MADRID - UNIVERSIDAD COMPLUTENSE DE MADRID - - - EUR 1 498 855 - - - Decentralized Blockchain-based Organizations for Bootstrapping the Collaborative Economy - - - EUR 1 498 855 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The Collaborative Economy (CE) is rapidly expanding through new forms of Internet labor and commerce, from Wikipedia to Kickstarter and Airbnb. However, it suffers from 3 main challenges: (1) Infrastructure: centralized - surveillance that the central hubs of information exercise over their users, (2) Governance: disempowered communities which do not have any decision-making influence over the platform, and (3) Economy: concentration of profits in a few major players - who do not proportionally redistribute them to the contributors. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Spain - - - P2PMODELS - - - ERC-2017-STG - - - 759207 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 1 499 616 - - - Bringing into focus the cellular dynamics of the plant growth hormone gibberellin - - - EUR 1 499 616 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - During an organism’s development it must integrate internal and external information. An example in plants, whose development stretches across their lifetime, is the coordination between environmental stimuli and endogenous - cues on regulating the key hormone gibberellin (GA). The present challenge is to understand how these diverse signals influence GA levels and how GA signalling leads to diverse GA responses. This challenge is deepened by a fundamental problem in - hormone research: the specific responses directed by a given hormone often depend on the cell-type, timing, and amount of hormone accumulation, but hormone concentrations are most often assessed at the organism or tissue level. Our approach, based on - a novel optogenetic biosensor, GA Perception Sensor 1 (GPS1), brings the goal of high-resolution quantification of GA in vivo within reach. In plants expressing GPS1, we observe gradients of GA in elongating root and shoot tissues. We now aim to - understand how a series of independently tunable enzymatic and transport activities combine to articulate the GA gradients that we observe. We further aim to discover the mechanisms by which endogenous and environmental signals regulate these GA - enzymes and transporters. Finally, we aim to understand how one of these signals, light, regulates GA patterns to influence dynamic cell growth and organ behavior. Our overarching goal is a systems level understanding of the signal integration - upstream and growth programming downstream of GA. The groundbreaking aspect of this proposal is our focus at the cellular level, and we are uniquely positioned to carry out our multidisciplinary aims involving biosensor engineering, innovative - imaging, and multiscale modelling. We anticipate that the discoveries stemming from this project will provide the detailed understanding necessary to make strategic interventions into GA dynamic patterning in crop plants for specific improvements in - growth, development, and environmental responses. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - CELL HORMONE - - - ERC-2017-STG - - - 759282 - - - - - UNIVERSITY OF NEWCASTLE UPON TYNE - UNIVERSITY OF NEWCASTLE UPON TYNE - - - EUR 1 499 250 - - - Endothelial RNA Modifications in Vascular Homeostasis and Disease - - - EUR 1 499 250 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Endothelial cells cover the entire arterial and venous tree, and play a pivotal role in vascular and organ homeostasis. In general, cardiovascular risk factors induce endothelial cell activation towards a pro-inflammatory - phenotype leading to atherosclerosis, a major cause of mortality in the Western world. Understanding the mechanisms that orchestrate endothelial cell functions and response to environmental stimuli is essential for the discovery and development of - novel biomarkers and therapeutic strategies in vascular disease. - - - 2023-05-31, Grant Agreement signed - - - 2018-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - MODVASC - - - ERC-2017-STG - - - 759248 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 437 188 - - - Understanding Type Ia SuperNovae for Accurate Cosmology - - - EUR 1 437 188 - - - France - France - - - Research Organisations - Research Organisations - - With this proposal I aim at removing astrophysical biases in SN cosmology that limit improvements in the derivation of properties of the dark energy (DE). DE is the cause of the recent acceleration of the expansion of the - Universe and accounts for ~70% of its total energy. The initial discovery based on distance measurements from Type Ia Supernovae (SNeIa) has since been confirmed with several independent probes. Today, the goal of cosmology is to understand the - nature of DE, and SNeIa remain a central probe for this endeavor. However, the nature of SNeIa remains largely unknown, which limits our ability to accurately trace the properties of the Universe. The proposed research program focuses on solving this - problem. - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - USNAC - - - ERC-2017-STG - - - 759194 - - - - - BAYERISCHE JULIUS-MAXIMILIANS UNIVERSITAT WURZBURG - BAYERISCHE JULIUS-MAXIMILIANS UNIVERSITAT WURZBURG - - - EUR 1 498 750 - - - Tissue-resident Lymphocytes: Development and Function in “real-life” Contexts - - - EUR 1 498 750 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Most anatomical compartments, including mucosal barrier surfaces, solid organs and vascular spaces host different types of tissue-resident lymphocytes providing local networks for immune surveillance and front-line defense to - microbial invasion. In addition to immediate effector functions, tissue-resident lymphocytes orchestrate and regulate inflammatory responses, and contribute to tissue homeostasis, repair and barrier function. Understanding the generation and function - of tissue-resident lymphocytes is therefore expected to reveal targets for improving vaccination and immunotherapy. Barrier tissues of free-living mice and men, but not those of laboratory mice kept under specific pathogen free conditions, are - continuously exposed to an array of antigenically complex pathogens, microbial symbionts and environmental factors, which dramatically alter the abundance, composition and basal activation state of local pools of tissue-resident cells. Therefore, we - propose to study the development, functions and cellular interactions of tissue-resident lymphocytes in experimental models that mirror “real-life” contexts. First, we will investigate how polyclonal pools of tissue-resident memory CD8+ T cells - (TRMs) are established during infection with antigenically complex pathogens. Second, we will restore physiologic exposure to specific pathogens and induce alterations of local microbiota in SPF mice, in order to investigate the induction, function - and local interactions of tissue-resident lymphocytes in physiologic tissue environments. In addition, we will explore targeted microbial exposure as a „vaccination“ strategy to induce „non-canonical“ tissue-resident cells in the lung in order to - improve protection against infections with multi-resistant bacteria representing major clinical problems in hospitalized patients. In summary, we will investigate fundamental mechanisms of tissue immunity and vaccination in contexts relevant for - human physiology and disease. - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - TissueLymphoContexts - - - ERC-2017-STG - - - 759176 - - - - - DEUTSCHE DIABETES FORSCHUNGSGESELLSCHAFT EV - DEUTSCHE DIABETES FORSCHUNGSGESELLSCHAFT EV - - - EUR 1 492 313,75 - - - Ceramide Synthases in Diabetic Beta Cell Demise - - - EUR 1 492 313,75 - - - Germany - Germany - - - Research Organisations - Research Organisations - - Sphingolipids including ceramides are building blocks of cell membranes, but also act as regulated intracellular messenger molecules. Emerging data indicate that sphingolipids are dynamically regulated by nutrients, and in - turn control systemic metabolism, for example, by modulating insulin secretion, proliferation and cell death of pancreatic beta cells. Dysfunction and death of beta cells are key events during the development of diabetes, from which more than 400 - million patients suffer worldwide. While pharmacological inhibition of general ceramide biosynthesis is protective against diabetes in animal studies, side effects of total loss of ceramides prevent medical implementation. The de novo synthesis of - ceramides is fully dependent on six ceramide synthase enzymes (CerS 1-6), which are expressed in a tissue specific manner, and generate ceramides with different chain lengths. Currently, the functional roles and regulatory modulators of each CerS are - unknown in pancreatic beta cells. Importantly, the downstream mechanisms by which ceramides impair beta cell function and eventually cause diabetes are not defined. Here, I propose to combine genomics, proteomics and lipidomics to assess the function - of ceramide synthases expressed in mouse and human beta cells. Furthermore, both the subcellular localisation and the post-translational modifications of CerS will be determined. The ceramide-interacting proteins mediating the deleterious effects of - ceramides will be identified by lipid-protein crosslinking and functionally tested. Finally, in a translational approach, we will test the ability of recently generated novel specific CerS inhibitors with improved specificity to ameliorate beta cell - stress, and improve insulin secretion in mouse and human beta cells. In sum, we will identify, characterize, validate and target ceramide synthases involved in beta cell biology and development of diabetes. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - CESYDE - - - ERC-2017-STG - - - 759099 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 1 376 080 - - - The Transformation of Post-War Education: Causes and Effects - - - EUR 1 376 080 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The educational context that children are born into dramatically shapes their life chances, affecting not only their future economic well-being but also their propensity to participate in civic and political life. That - education matters is hardly a new insight; however, an increasing body of research points to the importance of varying educational contexts on a range of outcomes. Despite these insights, we have little systematic comparative data on the educational - contexts in which most the current adult population was actually educated, the political determinants of these contexts, or their long-term impact on a range of social and political outcomes. SCHOOLPOL proposes three innovative and high-reward work - streams aimed at filling these lacunae. It will create the first systematic database of a) educational policy from 1945-2015 and b) regional educational performance from 1980-2015 across advanced democracies. Building on insights from both - sociological studies of educational choice, economic analyses of geographic sorting, and recent work in political science on educational investment, SCHOOLPOL will reshape our understanding of education politics, showing how broad public objectives - (growth, equality) in educational provision interact with the private objectives of organized groups and voters in particular communities to shape different distributions of educational resources and quality. Finally, SCHOOLPOL investigates the - consequences of earlier political choices over education on long-term social and economic outcomes, examining the link between varying cohort educational experiences and social mobility and political participation using new and existing surveys. This - innovative project breaks new ground in both the study of education and advanced political economies, providing crucial resources to policymakers and academics alike in understanding and crafting school reform. - - 2023-04-30, Grant Agreement signed - - - 2018-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - SCHOOLPOL - - - ERC-2017-STG - - - 759188 - - - - - UPPSALA UNIVERSITET - UPPSALA UNIVERSITET - - - EUR 1 491 013 - - - 1D-electrons coupled to dissipation: a novel approach for understanding and engineering superconducting materials and devices - - - EUR 1 491 013 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Correlated electrons are at the forefront of condensed matter theory. Interacting quasi-1D electrons have seen vast progress in analytical and numerical theory, and thus in fundamental understanding and quantitative - prediction. Yet, in the 1D limit fluctuations preclude important technological use, particularly of superconductors. In contrast, high-Tc superconductors in 2D/3D are not precluded by fluctuations, but lack a fundamental theory, making prediction and - engineering of their properties, a major goal in physics, very difficult. This project aims to combine the advantages of both areas by making major progress in the theory of quasi-1D electrons coupled to an electron bath, in part building on recent - breakthroughs (with the PIs extensive involvement) in simulating 1D and 2D electrons with parallelized density matrix renormalization group (pDMRG) numerics. Such theory will fundamentally advance the study of open electron systems, and show how to - use 1D materials as elements of new superconducting (SC) devices and materials: 1) It will enable a new state of matter, 1D electrons with true SC order. Fluctuations from the electronic liquid, such as graphene, could also enable nanoscale wires to - appear SC at high temperatures. 2) A new approach for the deliberate engineering of a high-Tc superconductor. In 1D, how electrons pair by repulsive interactions is understood and can be predicted. Stabilization by reservoir - formed by a parallel - array of many such 1D systems - offers a superconductor for which all factors setting Tc are known and can be optimized. 3) Many existing superconductors with repulsive electron pairing, all presently not understood, can be cast as 1D electrons - coupled to a bath. Developing chain-DMFT theory based on pDMRG will allow these materials SC properties to be simulated and understood for the first time. 4) The insights gained will be translated to 2D superconductors to study how they could be - enhanced by contact with electronic liquids. - - 2023-09-30, Grant Agreement signed - - - 2018-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Sweden - - - 1D-Engine - - - ERC-2017-STG - - - 758935 - - - - - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - - - EUR 1 499 410 - - - GUIDANCE AND FUNCTION OF REGENERATIVE FIBERS IN ADULT CNS - - - EUR 1 499 410 - - - France - France - - - Research Organisations - Research Organisations - - The impairment of central nervous system (CNS) leads to irreversible loss of vital functions because, unlike young neurons, mature neurons are not able to regenerate. Thus, understanding the detailed mechanisms of axonal - growth and repair remains one of the greatest challenges of neurobiology and for society. If the extrinsic factors fail to reach levels required for regeneration, manipulating intrinsic pathways has shown promising results. Particularly, my work - demonstrated that the simultaneous activation of mTOR, JAK/STAT and c-myc pathways allows exceptional regeneration with axons close to their targets. However it also exacerbates previously described phenomenon of misguidance with potential aberrant - circuit formation. My unique model opens up the possibility to explore these fundamental questions of CNS regeneration. I propose to address the yet unexplored problem of the guidance of regenerating axons in adults in order to promote the formation - of a functional new circuit after injury. Indeed what are the modalities of guidance in the adult? Are axons still responsive to developmental guidance cues and are they still expressed? Can regenerative axons form connections with their targets and - are these connections functional? - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - DRIVE - - - ERC-2017-STG - - - 759089 - - - - - JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN - JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN - - - EUR 1 416 934 - - - Predictive Memory Systems Across the Human Lifespan - - - EUR 1 416 934 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - As neuroscientific findings on brain functions accumulate, it is increasingly important to derive a set of overarching general principles about how the human brain works. For this, the predictive coding framework emerges as a - promising route, with the notion that the brain operates as a prediction machine; internal models in the brain predict future states against which incoming information of new experience is compared. - - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - PIVOTAL - - - ERC-2017-STG - - - 758898 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 1 486 938 - - - Functional Biointerface Elements via Biomicrofabrication - - - EUR 1 486 938 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Imagine in the future, bionic devices that can merge device and biology which can perform molecular sensing, simulate the functions of grown-organs in the lab, or even replace or improve parts of the organ as smart implants? - Such bionic devices is set to transform a number of emerging fields, including synthetic biotechnology, regenerative medicine, and human-machine interfaces. Merging biology and man-made devices also mean that materials of vastly different properties - need to be seamlessly integrated. One of the promising strategies to manufacture these devices is through 3D printing, which can structure different materials into functional devices, and simultaneously intertwining with biological matters. However, - the requirement for biocompatibility, miniaturisation, portability and high performance in bionic devices pushes the current limit for micro- nanoscale 3D printing. - - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - BIOELE - - - ERC-2017-STG - - - 758865 - - - - - UNIVERSITAT ZURICH - UNIVERSITAT ZURICH - - - EUR 1 288 125 - - - Tax Evasion in Developing Countries. The Role of Firm Networks - - - EUR 1 288 125 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Tax evasion leads to billions of Euros of losses in government revenue around the world. This does not only affect public budgets, but can also create large distortions between activities that are fully taxed and others that - escape taxation through evasion. These issues are particularly severe in developing countries, where evasion is especially high and governments struggle to raise funds for basic services and infrastructure, while at the same time trying to grow - independent of international aid. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Switzerland - - - DEVTAXNET - - - ERC-2017-STG - - - 758984 - - - - - UNIVERSITEIT MAASTRICHT - UNIVERSITEIT MAASTRICHT - - - EUR 148 530 - - - Reading the mind’s eye at 7 Tesla - A fMRI-based communication brain-computer interface for severely motor-impaired patients - - - EUR 148 530 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The Advanced ERC project ColumnarCodeCracking has pioneered ultra-high field fMRI at 7 Tesla for sub-millimeter neuroscience applications targeting cortical columns and cortical layers. One sub-project of the ERC project was - to explore whether it is possible to build new brain computer interfaces (BCIs) exploiting the strong signal quality and higher resolution achievable at ultra-high magnetic fields. As part of our research (Emmerling et al., 2017, - http://cordis.europa.eu/news/rcn/124885_en.html) we discovered that it is possible to reconstruct letter shapes from activity in early visual areas that are merely imagined by participants during 7 Tesla fMRI scanning. Importantly, we could - demonstrate that imagined letter shapes can be decoded from single imagination events of about 10 seconds without the need to average across multiple repetitions. These observations stimulated the idea for this PoC application, namely to use letter - imagery for the first time as a communication BCI. We also have tested deep learning auto-encoder networks as part of the analysis and observed that these tools substantially increase the robustness of letter reconstruction. The three major goals of - this PoC are 1) to perform 7 Tesla fMRI experiments with healthy participants to evaluate whether decoding brain activity patterns during letter imagery can be performed robust enough to be used as a communication BCI for severely motor-impaired - (locked-in) patients, 2) to develop a BCI/neurofeedback software performing all required advanced online analyses, and 3) evaluate whether showing the online decoded letter during imagery helps participants to fine-tune the resulting shape. While 7 - Tesla fMRI is not yet widely available in clinical settings, we aim to prepare first tests of the developed prototype with locked-in patients. - - 2019-06-30, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Netherlands - - - MindsEyeBCI - - - ERC-2017-PoC - - - 779860 - - - - - UNIVERSITEIT VAN AMSTERDAM - UNIVERSITEIT VAN AMSTERDAM - - - EUR 1 499 664 - - - Politics and Emotions Investigated Comparatively - - - EUR 1 499 664 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Many claim that politicians make more, and more extreme, emotional appeals than ever before, because these appeals win over the emotional citizen. With highly emotive language people like Donald Trump, Geert Wilders or Marine - Le Pen are pounding on the portals to power. Do such emotional appeals affect citizens’ political choices? Yes, they can. But, citizens’ existing emotional attachments to parties, leaders or issues moderate the success of emotional appeals. POLEMIC - will extend existing theory and use novel methods to explain when (types of) emotional appeals are persuasive, and when emotional attachments prevent persuasion. - - 2023-03-31, Grant Agreement signed - - - 2018-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - POLEMIC - - - ERC-2017-STG - - - 759079 - - - - - STICHTING KATHOLIEKE UNIVERSITEIT - STICHTING KATHOLIEKE UNIVERSITEIT - - - EUR 1 500 000 - - - New Chemical Tools for Precision Glycotherapy - - - EUR 1 500 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Glycosylation, the expression of carbohydrate structures on proteins and lipids, is found in all the domains of life. The collection of all glycans found on a cell is called the “glycome” which is information rich and a key - player in a plethora of physiological and pathological processes. The information that the glycome holds can be written, read and erased by glycosyltransferases, lectins and glycosidases, respectively. The immense structural complexity and the fact - that glycan biosynthesis is not under direct genetic control makes it very difficult to study the glycome. - - 2022-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - GlycoEdit - - - ERC-2017-STG - - - 758913 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 500 000 - - - Reconstructing human cortex development and malformation with single-cell transcriptomics - - - EUR 1 500 000 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Technologies to sequence single-cell transcriptomes (scRNA-seq) are revolutionizing our ability to analyze cell composition and differentiation in complex tissues. In parallel, recent innovations allow the generation of - three-dimensional tissues from stem cells that recapitulate human development. In this proposal, we will focus on human cortex development modelled by cerebral organoids. Our vision is to create an integrative single-cell transcriptomic platform to - reconstruct cerebral organoid development, and dissect network alterations that lead to human brain malformations. Our project will be advanced through the following objectives: - - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - ORGANOMICS - - - ERC-2017-STG - - - 758877 - - - - - CENTRE INTERNACIONAL DE METODES NUMERICS EN ENGINYERIA - CENTRE INTERNACIONAL DE METODES NUMERICS EN ENGINYERIA - - - EUR 149 991 - - - Computational catalog of multiscale materials: a plugin library for industrial finiteelement codes - - - EUR 149 991 - - - Spain - Spain - - - Research Organisations - Research Organisations - - The Proof of Concept CATALOG will explore the industrial applicability and potential for commercialization of a prototype of a “computational multiscale material catalog”, to exploit HPROM (high‐performance reduced order - modeling), a technology developed in the ERC Advanced Grant COMP-DES-MAT for advanced material simulation. CATALOG will provide extremely fast and accurate multiscale capabilities to existing commercial Finite Element Analysis Solvers (FEAS), greatly - enhancing their standard simulation performance. This solution effectively addresses the current need for high-performance simulations, currently not provided by established multiscale approaches. - - 2019-06-30, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Spain - - - CATALOG - - - ERC-2017-PoC - - - 779611 - - - - - UNIVERSIDAD AUTONOMA DE MADRID - UNIVERSIDAD AUTONOMA DE MADRID - - - EUR 1 499 719 - - - 4-Colours/2-Junctions of III-V semiconductors on Si to use in electronics devices and solar cells - - - EUR 1 499 719 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - It was early predicted by M. Green and coeval colleagues that dividing the solar spectrum into narrow ranges of colours is the most efficient manner to convert solar energy into electrical power. Multijunction solar cells are - the current solution to this challenge, which have reached over 30% conversion efficiencies by stacking 3 junctions together. However, the large fabrication costs and time hinders their use in everyday life. It has been shown that highly mismatched - alloy (HMA) materials provide a powerful playground to achieve at least 3 different colour absorption regions that enable optimised energy conversion with just one junction. Combining HMA-based junctions with standard Silicon solar cells will rocket - solar conversion efficiency at a reduced price. To turn this ambition into marketable devices, several efforts are still needed and few challenges must be overcome. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Spain - - - 4SUNS - - - ERC-2017-STG - - - 758885 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 1 499 585 - - - Photon Management for Solar Energy Harvesting with Hybrid Excitonics - - - EUR 1 499 585 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In nature, biological light harvesting complexes use antennas molecules to harvest photons, generate excitons and then funnel them to the reaction centre where their energy is used to drive photosynthesis. Inspired by this - paradigm, SOLARX will explore new strategies for photon management in solar energy harvesting, based on the transfer and manipulation of excitons at hybrid interfaces. At the core of SOLARX is our development of a new femtosecond transient absorption - imaging technique with sub-10fs time resolution and sub-diffraction limit spatial resolution. This opens completely new possibilities to explore excitonic physics at the nanoscale, directly visualising not just the motion of excitons but - understanding how vibronic coupling and local structure affects their dynamics. Building on this platform we will deliver ground-breaking new insights into excitonic process in and at the interfaces between organic semiconductors, quantum dots, 2D - monolayer semiconductors and lanthanide doped nanoparticles. We will elucidate the fundamental nanoscale dynamics of: (1) endothermic singlet fission, (2) the injection of triplet excitons into lanthanide doped nanoparticles and (3) the motion of - excitons in 2D monolayer semiconductors and how these excitons can be funnelled over µm length scales to be transferred to quantum dots. We will then use these insights to develop proof of concept demonstrations of structures which harvest photons - across the visible and NIR, efficiently converting high energy visible photons to two NIR photons and then concentrating these photons within structures with the potential to achieve concentration factors well above 100, thus concentrating light to - drastically reduce the number of PV panels and hence dramatically reducing the cost of solar energy. SOLARX will thus explore and elucidate fundamental new excitonic physics and use these insights to bring a paradigm shift to solar energy harvesting - technologies. - - 2023-03-31, Grant Agreement signed - - - 2018-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - SOLARX - - - ERC-2017-STG - - - 758826 - - - - - UNIVERSITY COLLEGE LONDON - UNIVERSITY COLLEGE LONDON - - - EUR 1 458 345 - - - Gauging the Risk of Incidents of Extremist Violence Against Non-Combatant Entities - - - EUR 1 458 345 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - GRIEVANCE seeks to make significant advances in increasing our understanding, and thereby reducing the risk, of extremist violence against non-combatants. An inter-disciplinary project underpinned by crime prevention - principles is needed to help quantify the risk of such offences. The barbarity of such violent acts, coupled with the fact that participation in them is characterised by an extremely low base rate, has led researchers to seek out individual qualities - of the offender with a particular focus upon what radicalisation is and how its drivers can be countered. This search has proven unproductive and impractical. In fact, it has most likely limited and unduly narrowed a wider consideration of the ways - in which social scientists can bring what conceptual tools we have to bear on the problem of controlling and managing such behaviour. By doing so, this project shifts the focus from individual qualities (what we think terrorists and other similar - offenders “are”) to a consideration of the situational qualities of their behaviour – in other words, what violent offenders do and how they do it (Horgan, 2009: 143). This is consistent with developments in the area of crime control (Cornish and - Clarke, 1986; Brantingham & Brantingham, 1981) and crime science more generally. More specifically, GRIEVANCE will utilise a number of unique datasets to understand the risk of extremist violence across a number of phases of analysis. GRIEVANCE - characterises risk in terms of a process and dedicates a work package (WP) to each stage of the process from the risk of radicalisation (WP1), to the risk of recruitment (WP2), to the risk of violent action (WP3), to the temporal (WP4) and spatial - (WP5) risk of offending behaviour followed by an assessment of the risk of adverse consequences from intervention (WP6). GRIEVANCE will both synthesise the existing knowledge within the literature and produce innovative new findings by utilising - cutting edge inter-disciplinary research methods. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - GRIEVANCE - - - ERC-2017-STG - - - 758834 - - - - - STICHTING KATHOLIEKE UNIVERSITEIT BRABANT - STICHTING KATHOLIEKE UNIVERSITEIT BRABANT - - - EUR 1 499 854 - - - The Time is Now: Understanding Social Network Dynamics Using Relational Event Histories - - - EUR 1 499 854 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Relational event history data are becoming increasingly available due to new technical developments. These data contain detailed information about who interacted with whom in a network and when. For example, employees wear - sociometric badges storing time-stamped interactions between colleagues, classrooms are monitored to observe interactions between teachers and students, and police databases store violent interactions between criminal gangs in city districts. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - TIMEISNOW - - - ERC-2017-STG - - - 758791 - - - - - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - - - EUR 1 500 000 - - - In vivo functional screens to decipher mechanisms of stochastically- and mutationally-induced chemoresistance in Acute Myeloid Leukemia - - - EUR 1 500 000 - - - France - France - - - Research Organisations - Research Organisations - - Acute Myeloid Leukemia (AML), the most common leukemia diagnosed in adults, represents the paradigm of resistance to front-line therapies in hematology. Indeed, AML is so genetically complex that only few targeted therapies - are currently tested in this disease and chemotherapy remains the only standard treatment for AML since the past four decades. Despite an initial sustained remission achieved by chemotherapeutic agents, almost all patients relapse with a - chemoresistant minimal residual disease (MRD). The goal of my proposal is to characterize the still poorly understood biological mechanisms underlying persistence and emergence of MRD. - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - AltCheM - - - ERC-2017-STG - - - 758848 - - - - - THE UNIVERSITY OF LIVERPOOL - THE UNIVERSITY OF LIVERPOOL - - - EUR 1 475 560 - - - Influence-based Decision-making in Uncertain Environments - - - EUR 1 475 560 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Decision-theoretic sequential decision making (SDM) is concerned with endowing an intelligent agent with the capability to choose actions that optimize task performance. SDM techniques have the potential to revolutionize many - aspects of society and recent successes, e.g., agents that play Atari games and beat a world champion in the game of Go, have sparked renewed interest in this field. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - INFLUENCE - - - ERC-2017-STG - - - 758824 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 476 672 - - - Theoretical and observational consequences of the Geometrical Destabilization of Inflation - - - EUR 1 476 672 - - - France - France - - - Research Organisations - Research Organisations - - The GEODESI project aims at interpreting current and forthcoming cosmological observations in a renewed theoretical framework about cosmological inflation and its ending. The simplest toy models of inflation economically - explain all current data, leaving no observational clue to guide theorists towards a finer physical understanding. In this context, I very recently unveiled an hitherto unnoticed instability at play in the primordial universe that potentially affects - all inflationary models and drastically modifies the interpretation of cosmological observations in terms of fundamental physics. The so-called Geometrical Destabilization of inflation reshuffles our understanding of the origin of structures in the - universe, offers a new mechanism to end inflation, and promises unrivaled constraints on high-energy physics. It is crucial to develop this fresh look before a host of high-quality data from large-scale structure surveys and cosmic microwave - background observations become available within the 5 year timescale of the project. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - GEODESI - - - ERC-2017-STG - - - 758792 - - - - - INSTITUT CURIE - INSTITUT CURIE - - - EUR 1 497 500 - - - A new paradigm for centromere biology:Evolution and mechanism of CenH3-independent chromosome segregation in holocentric insects - - - EUR 1 497 500 - - - France - France - - - Research Organisations - Research Organisations - - Faithful chromosome segregation in all eukaryotes relies on centromeres, the chromosomal sites that recruit kinetochore proteins and mediate spindle attachment during cell division. Fundamental to centromere function is a - histone H3 variant, CenH3, that initiates kinetochore assembly on centromeric DNA. CenH3 is conserved throughout most eukaryotes; its deletion is lethal in all organisms tested. These findings established the paradigm that CenH3 is an absolute - requirement for centromere function. My recent findings undermined this paradigm of CenH3 essentiality. I showed that CenH3 was lost independently in four lineages of insects. These losses are concomitant with dramatic changes in their centromeric - architecture, in which each lineage independently transitioned from monocentromeres (where microtubules attach to a single chromosomal region) to holocentromeres (where microtubules attach along the entire length of the chromosome). Here, I aim to - characterize this unique CenH3-deficient chromosome segregation pathway. Using proteomic and genomic approaches in lepidopteran cell lines, I will determine the mechanism of CenH3-independent kinetochore assembly that led to the establishment of - their holocentric architecture. Using comparative genomic approaches, I will determine whether this kinetochore assembly pathway has recurrently evolved over the course of 400 million years of evolution and its impact on the chromosome segregation - machinery. - - 2023-03-31, Grant Agreement signed - - - 2018-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - CENEVO - - - ERC-2017-STG - - - 758757 - - - - - UNIVERSITY OF BRISTOL - UNIVERSITY OF BRISTOL - - - EUR 1 499 611 - - - Genetic, behavioural and cognitive mechanisms underpinning the association between mother and offspring mental health problems: mental (M) health (H) intergenerational transmission (INT) -(MHINT) - - - EUR 1 499 611 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Despite decades of research, and the introduction of parenting interventions, children of mentally ill mothers remain substantially more likely to have mental health problems themselves. I propose to shed new light on why - mental health problems in a mother are passed on to her child, and help break this reinforcing cycle of mental health risk across generations. In order to harness the potential of modifying parenting for the prevention of child mental health risk, I - will study parenting using more detailed, ecologically valid and genetically sensitive designs than have been done before. - - 2022-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - MHINT - - - ERC-2017-STG - - - 758813 - - - - - ECOLE POLYTECHNIQUE - ECOLE POLYTECHNIQUE - - - EUR 1 498 028,42 - - - Hydrodynamics, holography and strongly-coupled quantum matter - - - EUR 1 498 028,42 - - - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The dynamics of weakly-coupled quantum matter can be solved by techniques deriving from perturbative quantum field theory. Conventional metals are described by long-lived quasiparticles (Fermi liquids). No such methods are - available for strongly-coupled quantum matter where quasiparticles are short-lived, like the Quark-Gluon-Plasma, high Tc superconductors (HTCs) or graphene near the charge neutrality point. - - 2023-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - HHQM - - - ERC-2017-STG - - - 758759 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN - - - EUR 149 945 - - - Articular cartilage regeneration through the recruitment of bone marrow derived mesenchymal stem cells into extracelluar matrix derived scaffolds anchored by 3D printed polymeric supports - - - EUR 149 945 - - - Ireland - Ireland - Ireland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Osteoarthritis (OA), the most common form of arthritis, is a serious disease of the joints affecting nearly 10% of the population worldwide. The onset of OA has been associated with defects to articular cartilage that lines - the bones of synovial joints. Current strategies to treat articular cartilage defects are ineffective and/or prohibitively expensive. The aim of ANCHOR is to develop and commercialise a new medicinal product for articular cartilage regeneration that - recruits endogenous bone marrow derived stem cells into an extracellular matrix derived scaffold anchored to the subchondral bone by 3D printed polymeric supports. By recruiting endogenous cells into a supporting scaffold, ANCHOR will obviate the - need for pre-seeding scaffolds with cells prior to implantation into cartilage defects, thereby dramatically reducing the cost and complexity of the repair procedure. It will also overcome the need for suturing of a scaffold into a cartilage defect, - which is a very time consuming and technically challenging surgical procedure. Finally, the inherent chondro-inductivity of the cartilage ECM derived scaffolds developed by the applicant will maximise the potential for hyaline cartilage regeneration. - The project will leverage the applicants extensive experience in ECM derived biomaterials and 3D printing to develop a new product with significant commercial potential. The impact of ANCHOR will be multi-faceted: it will transform how damaged joints - are treated by orthopaedic surgeons, it will create economic value through the commercialization of IP, and most importantly it will improve patient experience and their long-term health and well-being. - - 2019-06-30, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Ireland - - - ANCHOR - - - ERC-2017-PoC - - - 779909 - - - - - UNIVERSITEIT MAASTRICHT - UNIVERSITEIT MAASTRICHT - - - EUR 150 000 - - - Smart wavy patterned implants with instructive properties for tissue regeneration by controllingthe degree of fibers buckling. - - - EUR 150 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In the pursuit for engineering CELL HYBRIDGE regenerative medicine implants able to regenerate skeletal tissues by controlling adult stem cell activity, we have developed an innovative method to successfully improve cell - migration into electrospun scaffolds. Whereas this has a direct impact in CELL HYBRIDGE as part of the planned activities, we unexpectedly discovered that the same scaffolds display wavy patterns that have a direct influence on cell differentiation - by enhancing their intrinsic capacity to produce growth factors. - - - 2019-06-30, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Netherlands - - - BUCKLING BRIDGES - - - ERC-2017-PoC - - - 779939 - - - - - THE HEBREW UNIVERSITY OF JERUSALEM - THE HEBREW UNIVERSITY OF JERUSALEM - - - EUR 1 500 000 - - - Dissecting Regulatory Networks That Mediate Dendritic Cell Suppression - - - EUR 1 500 000 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Recent advances have shown that therapeutic manipulations of key cell-cell interactions can have dramatic clinical outcomes. Most notable are several early successes in cancer immunotherapy that target the tumor-T cell - interface. However, these successes were only partial. This is likely because the few known interactions are just a few pieces of a much larger puzzle, involving additional signaling molecules and cell types. Dendritic cells (DCs), play critical - roles in the induction/suppression of T cells. At early cancer stages, DCs capture tumor antigens and present them to T cells. However, in advanced cancers, the tumor microenvironment (TME) disrupts the crosstalk between DCs and T cells. - - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Israel - - - CANCER-DC - - - ERC-2017-STG - - - 758735 - - - - - THE QUEEN'S UNIVERSITY OF BELFAST - THE QUEEN'S UNIVERSITY OF BELFAST - - - EUR 1 876 496 - - - Type Ia supernovae: from explosions to cosmology - - - EUR 1 876 496 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Type Ia supernovae (SNe Ia) are the incredibly luminous deaths of white dwarfs in binaries. They play a vital role in chemical enrichment, galaxy feedback, stellar evolution, and were instrumental in the discovery of dark - energy. However, what are the progenitor systems of SNe Ia, and how they explode remains a mystery. My recent work has concluded the controversial result that there may be more than one way to produce SNe Ia. As SN Ia cosmology samples reach higher - precision, understanding subtle differences in their properties becomes increasingly important. A surprising diversity in white-dwarf explosions has also been uncovered, with a much wider-than-expected range in luminosities, light-curve timescales - and spectral properties. A key open question is ‘What explosion mechanisms result in normal SNe Ia compared to more exotic transients?’ - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - SUPERSTARS - - - ERC-2017-STG - - - 758638 - - - - - UNIVERSIDAD CARLOS III DE MADRID - UNIVERSIDAD CARLOS III DE MADRID - UNIVERSIDAD NACIONAL DE EDUCACION A DISTANCIA - WISSENSCHAFTSZENTRUM BERLIN FUR SOZIALFORSCHUNG GGMBH - - - EUR 1 499 572 - - - Effort and Social Inequality: Advancing Measurement and Understanding Parental Origin Effects - - - EUR 1 499 572 - - - Spain - Spain - Spain - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - This project aims to understand the role of effort in the reproduction of social inequality. While large-scale test programs like PISA have produced impressive amounts of data on the determinants of cognitive abilities, there - is scant evidence on socio-economic differences in cognitive effort. Better understanding the social origins of effort pushes the frontier of knowledge on intergenerational mobility and allows improving equality of opportunity. Specifically, the aim - of the project is to answer three research questions: - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Spain - - - EFFORT - - - ERC-2017-STG - - - 758600 - - - - - UNIVERSITAETSKLINIKUM HAMBURG-EPPENDORF - UNIVERSITAETSKLINIKUM HAMBURG-EPPENDORF - - - EUR 1 490 825 - - - Development of strategies to eliminate cancer cells from the bone marrow - - - EUR 1 490 825 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The bone marrow (BM) represents the prime location in which cancer cells survive aggressive treatments. This poses a major health challenge because the mortality rate of patients with curable cancer doubles if tumor cells - persist in the BM. One unresolved question is why the immune system fails to eradicate cancer cells from this microenvironment even though it represents a lymphatic organ. Surprisingly, despite the ongoing revolution in immune oncology, the - regulation and potential therapeutic activation of the immune response in the BM still remains largely unexplored. In this grant application a new line of research is proposed with the overall objective of understanding the cellular and molecular - mechanisms, which control anti-cancer immune responses in the BM. The originality of this proposal relates to the hypothesis that innate and adaptive immune cells are suppressed by stroma cells in the BM. Therefore, we will conduct a comprehensive - phenotypic and functional profiling of immune and stroma cells in the BM of cancer patients with and without persisting tumor cells. Based on these insights we will develop novel strategies to harness the immune system to eliminate malignant cells - from the BM. The ground-breaking nature of the project is that it will shed light on the unappreciated immune microenvironment in the BM. Its specific strength lies in the multidisciplinary design encompassing informative patient cohorts, - state-of-the-art mouse models and cutting-edge technologies including Next-Generation-Sequencing as well as innovative drug candidates. Hereby I can build on my internationally recognized expertise in the BM microenvironment field, which has already - led to the successful development of a clinical-stage drug. Novel strategies to eliminate malignant cells from the bone marrow are of utmost medical importance because they would increase the cure rate of cancer patients. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - ELIMINATE - - - ERC-2017-STG - - - 758713 - - - - - THE UNIVERSITY OF EDINBURGH - THE UNIVERSITY OF EDINBURGH - - - EUR 1 481 154 - - - The emergence and evolution of linguistic tone - - - EUR 1 481 154 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project will investigate the origins, acquisition, and evolution of linguistic tone: the use of pitch to distinguish between the meaning of words. Despite the typological ubiquity of tone, there is still no phonetic, - structural, or psychological model that explains how and why tones emerge (or fail to emerge) in language after language, nor how they evolve once they are formed. This is because there has never been a systematic analysis of the principles that - govern the evolution of tone systems. EVOTONE will provide the first comprehensive study of tonal emergence and evolution, combining detailed phonetic and perceptual studies of Himalayan and Southeast Asian minority languages with innovative - experimental methodologies and large-scale computational analysis of the structural principles correlated with the emergence of tone. - - - 2023-05-31, Grant Agreement signed - - - 2018-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - EVOTONE - - - ERC-2017-STG - - - 758605 - - - - - DANMARKS TEKNISKE UNIVERSITET - DANMARKS TEKNISKE UNIVERSITET - - - EUR 1 496 000 - - - ATOMic Insight Cavity Array Reactor - - - EUR 1 496 000 - - - Denmark - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The goal of ATOMICAR is to achieve the ultimate sensitivity limit in heterogeneous catalysis: - - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Denmark - - - ATOMICAR - - - ERC-2017-STG - - - 758495 - - - - - HELSINGIN YLIOPISTO - HELSINGIN YLIOPISTO - - - EUR 1 470 665 - - - Competence and Success in Epistemology and Beyond - - - EUR 1 470 665 - - - Finland - Finland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project formulates and defends a novel approach in epistemology, demonstrating how it solves a range of key problems in the field. New frontiers of research are opened up by applying the core lessons learnt in - epistemology to the study of practical reason and ethics. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Finland - - - EpComp - - - ERC-2017-STG - - - 758539 - - - - - FUNDACION BCMATERIALS - BASQUE CENTRE FOR MATERIALS, APPLICATIONS AND NANOSTRUCTURES - UNIVERSITA DEGLI STUDI DI TORINO - UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA - AGENCIA VASCA DEL AGUA URA - TEKNIMAP AMBIENTAL SL - UNIVERSIDAD DE BUENOS AIRES - UNIVERSIDAD DE CHILE - THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - - - EUR 774 000 - - - International Network on Ionic Liquid Deep Eutectic Solvent Based Metal Organic Frameworks Mixed Matrix Membranes. - - - EUR 774 000 - - - Spain - Italy - Spain - Spain - Spain - Argentina - Chile - United States - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The main objective of INDESMOF Marie Curie RISE action is to establish a new and lasting research consortium to improve and exchange interdisciplinary and intersectoral knowledge on the design, synthesis, and characterization - of advanced composite adsorbents for environmental remediation of heavy metal polluted water sources, able to provide high capacity and high selectivity filters for the industry. The main research core of INDESMOF is based on the nano-encapsulation - of Deep Eutectic Solvents (DES) within the ordered porous structures of Metal Organic Frameworks (MOF), in order to obtain a highly porous MOF material, combined with the metal chelation and solvation specificity of DES. Incorporation of - high-capacity high-selectivity adsorbent materials within polymeric support is a crucial challenge faces in INDESMOF towards the real application of the MOF@DES materials in water filtering systems, indispensable for mining and industrial water - environmental remediation technologies. Development and improvement of advanced filtering technologies requires the joint effort of a multidisciplinary researcher collective, involving the expertise of participants on different disciplines including - physics, chemistry, environmental chemistry, materials and polymer science and engineering. Background knowledge and knowhow of INDEMOF´s partners combine the complementarities and synergies needed to undertake an integrative and concerted effort - through innovation and breakthrough actions towards the fabrication of advanced and specific filters for polluted water remediation. Results will be widely disseminated through publications, workshops, post-graduate courses to train new researchers, - a dedicated webpage, and visits to companies working in the area. In that way, we will perform an important role in technology transfer in the design of highly active and selective adsorbents and their performance against real water polluted samples. - - 2022-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Spain - - - INDESMOF - - - H2020-MSCA-RISE-2017 - - - 778412 - - - - - STOCKHOLMS UNIVERSITET - STOCKHOLMS UNIVERSITET - - - EUR 1 497 650,02 - - - MicroRNA functions in single cells - - - EUR 1 497 650,02 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - It is now becoming apparent that genes are regulated not only by transcription, but also by thousands of post-transcriptional regulators that can stabilize or degrade mRNAs. Some of the most important regulators are miRNAs, - short RNA molecules that are deeply conserved in sequence and are involved in numerous biological processes, including human disease. Surprisingly, transcriptomic and proteomic studies show that most miRNAs only have subtle silencing effects on their - targets, suggesting additional important, but yet undiscovered functions. Thus the question is raised: if the main function of miRNAs is not to silence targets, what is it? - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Sweden - - - miRCell - - - ERC-2017-STG - - - 758397 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 499 922 - - - Deconstructing pain with predictive models: from neural architecture to pain relief - - - EUR 1 499 922 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Pain is a burden for millions of people in terms of suffering, as well as for society in terms of costs. While it is well established that the perception of pain is not necessarily related to the amount of sensory input, a - mechanistic framework for this is still lacking at the neurobiological level, although it would be of utmost importance for inspiring new therapeutic approaches. In PredictingPain, I will provide such a framework by applying recent insights from - computational neuroscience in the form of ‘predictive coding’ to pain. Predictive coding models assume that perception is an active process in which the brain is not just passively responding to sensory inputs, but is instead constantly generating - predictions about its sensory inputs. - - 2023-09-30, Grant Agreement signed - - - 2018-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - PredictingPain - - - ERC-2017-STG - - - 758974 - - - - - UNIVERSITE DE LAUSANNE - UNIVERSITE DE LAUSANNE - - - EUR 1 499 885 - - - Transcriptional controls over cerebellar neuron differentiation and circuit assembly - - - EUR 1 499 885 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The cerebellum is a critical regulator of motor function, which acts to integrate ongoing body states, sensory inputs and desired outcomes to adjust motor output. This motor control is achieved by a relatively small number of - neuron types receiving two main sources of inputs and forming a single output pathway, the axons of Purkinje cells. Although the cerebellum is one of the first structures of the brain to differentiate, it undergoes a prolonged differentiation period - such that mature cellular and circuit configuration is achieved only late after birth. Despite the functional importance of this structure, the molecular mechanisms that control type-specific cerebellar neurons generation, differentiation, and - circuit assembly are poorly understood and are the topic of the present study. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Switzerland - - - CERDEV - - - ERC-2017-STG - - - 759112 - - - - - HELSINGIN YLIOPISTO - HELSINGIN YLIOPISTO - - - EUR 1 495 584 - - - Digital Grammar of Greek Documentary Papyri - - - EUR 1 495 584 - - - Finland - Finland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The project creates a new Digital Grammar of Greek Documentary Papyri. It fills a void in Greek scholarship: the papyrological corpus represents the Post-Classical variety of Greek, a bridge between Classical and Medieval - Greek, which has hitherto been very difficult to use as a source for studying historical linguistics. This project will develop new digital methods for studying this fragmentary but vast text corpus. - - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Finland - - - PapyGreek - - - ERC-2017-STG - - - 758481 - - - - - NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA - ARKEMA FRANCE - UNIVERSITY OF SURREY - STICHTING WAGENINGEN RESEARCH - DANMARKS TEKNISKE UNIVERSITET - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - GREENE WASTE TO ENERGY SL - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - CHALMERS TEKNISKA HOEGSKOLA AB - IBJ TECHNOLOGY IVS - BIOPROCESS PILOT FACILITY BV - CHIMAR HELLAS AE - COMPAGNIE INDUSTRIELLE DE LA MATIERE VEGETAL CIM V - - - EUR 666 000 - - - Renewable systems engineering for waste valorisation ΙΙ - - - EUR 666 000 - - - Greece - France - United Kingdom - Netherlands - Denmark - Switzerland - Spain - United Kingdom - Sweden - Denmark - Netherlands - Greece - France - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The project goal is to further advance the emerging area of Bio - process - systems engineering (BPSE) by capitalizing the recent advances and ITN of RENESENG (FP7 - PEOPLE - ITN) toward the following project objectives : - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Greece - - - RENESENG II - - - H2020-MSCA-RISE-2017 - - - 778332 - - - - - UNIVERSIDAD DE GRANADA - UNIVERSITE DES SCIENCES ET TECHNOLOGIES DE LILLE - LILLE I - GENERALIZED RETRIEVAL OF ATMOSPHERE AND SURFACE PROPERTIES EN ABREGE GRASP - UNIVERSIDAD DE VALLADOLID - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - FREIE UNIVERSITAET BERLIN - Goddard Space Flight Center - University System of Maryland - A.M. Prokhorov General Physics Institute of Russian Academy of Sciences - B.I. Stepanov Institute of Physics of the National Academy of Sciences of Belarus - - - EUR 877 500 - - - Development of GRASP radiative transfer code for the retrieval of aerosol microphysics vertical-profiles from space measurements and its impact in ACE mission - - - EUR 877 500 - - - Spain - France - France - Spain - France - Germany - Belgium - United States - Russia - Belarus - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Other - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - This project deals with reducing the uncertainties associated with the knowledge of aerosol microphysical vertical profiles worldwide through the use of new space-borne measurements. This objective links with the goal of the - last IPCC 2013 to reduce uncertainties in aerosol direct effects, particularly in the knowing of absorption profiles. The approach we plan to develop is the development and applicability of the Generalized Retrieval of Atmosphere and Surface - Properties (GRASP) for new space borne systems. GRASP has been already applied successfully to the POLDER/PARASOL system providing column-integrated aerosol microphysics and absorption. However, the new LIDAR space-borne sensors open new - possibilities. To that end, we plan to study the details in constraints of the current techniques for the retrieval of aerosol microphysics from multi-wavelength lidar alone (known as the 3b+2a configuration), and will make evaluation studies versus - in-situ instruments from large field campaigns such as DISCOVER-AQ and SEACR4S from NASA or SHADOW from the University of Lille. However, lidar measurements are difficult and usually presents low signal-to-noise ratio, particularly during daytime. We - plan here to develop a joint inversion that uses combine measurements of lidar and polarimetric space-borne systems. Such approach is the core of the upcoming Aerosol-Clouds-Ecosystems (ACE) NASA mission. The development of this task will involve the - use of synthetic database simulated using the NASA GEOS-5 model which will be used as reference. Different configurations of lidar and polarimeters will be studied to invert microphysical parameters. The results of this task will be also used for - defining cost-effective ACE mission. Also, joint inversion will be evaluated using experimental measurements on NASA field campaigns that include airborne lidar systems such as HSRL-2 and Airborne Cloud-Aerosol Transport System (ACATS) and - polarimeters such as the Multiangle SpectroPolarimetric. - - 2022-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Spain - - - GRASP-ACE - - - H2020-MSCA-RISE-2017 - - - 778349 - - - - - ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS - AGRICULTURAL UNIVERSITY OF ATHENS - FONDAZIONE EDMUND MACH - BIONOS BIOTECH SL - IGV GREENFOOD GGMBH - EPARELLA GMBH - FRESH FORMULA PRIVATE LIMITED COSMETICS MANUFACTURING COMPANY - - - EUR 1 129 500 - - - Development of microalgae-based natural UV Sunscreens and Proteins as cosmeceuticals and nutraceuticals - - - EUR 1 129 500 - - - Greece - Greece - Italy - Spain - Germany - Austria - Greece - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The biotechnology of microalgae has gained considerable importance in recent decades, as they represent a largely untapped reservoir of novel and valuable bioactive compounds. The biological and chemical diversity of the - microalgae, has been the source of unique bioactive molecules with the potential for industrial development as pharmaceuticals, cosmetics, nutritional supplements. The proposed project will combine both basic and applied research in the fields of - –omics technologies, biochemistry, applied and enzyme biotechnology in order to exploit microalgae resources for the development: 1) Natural UV sunscreens, based on algae mycosporine-like aminoacids, 2) Algae-based nutraceuticals as functional foods - and food supplements, 3) Algae-derived proteases with applications in cosmetic (skin repair enzymes) and food industry. The implementation of the project will offer to the involved academic and SMSs the opportunity to translate scientific research - into well defined knowledge-based ‘green’ products and analytical tools. Apart from scientific objectives, the project will enhance the European’s capacity in the field of Blue Growth and Marine Biotechnology by exchanging interdisciplinary - knowledge, developing and disseminating joint research activities, thus strengthening the intersectoral links between academia and industry for sustainable growth. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Greece - - - AlgaeCeuticals - - - H2020-MSCA-RISE-2017 - - - 778263 - - - - - THE UNIVERSITY OF SHEFFIELD - VYSOKE UCENI TECHNICKE V BRNE - UNIVERSITA DEGLI STUDI DI PAVIA - TECHNISCHE UNIVERSITEIT DELFT - NV PWN WATERLEIDINGBEDRIJF NOORD-HOLLAND - DVGW DEUTSCHER VEREIN DES GAS- UND WASSERFACHES - TECHNISCH-WISSENSCHAFTLICHER VEREIN EV - UNIVERSITAT POLITECNICA DE VALENCIA - STICHTING WATERNET - KWR WATER B.V. - INSTITUT NATIONAL DE RECHERCHE EN SCIENCES ET TECHNOLOGIES POUR L'ENVIRONNEMENT ET L'AGRICULTURE - THE UNIVERSITY OF EXETER - NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU - FACULTY OF CIVIL ENGINEERING - JAVNO KOMUNALNO PREDUZECE VODOVOD IKANALIZACJA PANCHEVO - CONSTRUCCIONES Y CANALIZACIONES CYCA SOCIEDAD LIMITADA - University of Cincinnati - REGENTS OF THE UNIVERSITY OF COLORADO - THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - - - EUR 243 000 - - - Water Quality in Drinking Water Distribution Systems. - - - EUR 243 000 - - - United Kingdom - Czech Republic - Italy - Netherlands - Netherlands - Germany - Spain - Netherlands - Netherlands - France - United Kingdom - Norway - Serbia - Serbia - Spain - United States - United States - United States - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Safe drinking water is paramount for the health and wellbeing of all populations. Unsafe drinking water can contain pathogenic microorganisms and/or chemicals that can make people immediately unwell or can potentially cause - serious illness over prolonged exposures. Within the EU, water is extracted from surface and groundwater sources and treated to comply with EU drinking water standards under the Water Framework Directive and Drinking Water Directive. The water is - then circulated through the drinking water distribution system (DWDS). During travel within the DWDS, water quality can deteriorate due to microbiological growth, chemical reactions, interactions with ageing and deteriorating infrastructure, and - through maintenance and repair activities. - - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - United Kingdom - - - Wat-Qual - - - H2020-MSCA-RISE-2017 - - - 778136 - - - - - UNIDAD NEURO-RHB SOCIEDAD LIMITADA - FUNDACION UNIVERSIDAD LOYOLA ANDALUCIA - FONDAZIONE SANTA LUCIA - ISTITUTI CLINICI SCIENTIFICI MAUGERI SOCIETA' PER AZIONI SOCIETA' BENEFIT - SCHON KLINIK BAD AIBLING SE & CO KG - ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON - UNIVERSITE DE LIEGE - UNIVERSITA DEGLI STUDI DELLA CAMPANIA LUIGI VANVITELLI - GUGER TECHNOLOGIES OG - UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA - - - EUR 1 129 500 - - - Disorders of Consciousness (DoC): enhancing the transfer of knowledge and professional skills on evidence-based interventions and validated technology for a better management of patients - - - EUR 1 129 500 - - - Spain - Spain - Italy - Italy - Germany - Greece - Belgium - Italy - Austria - Italy - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - The overall goal of DoCMA is to enhance international research on Disorders of Consciousness (DoC) by strengthen the collaboration among project participants to leverage the shared scientific and expert know-how in the field. - - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Spain - - - DoCMA - - - H2020-MSCA-RISE-2017 - - - 778234 - - - - - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - ECOLE NATIONALE DES PONTS ET CHAUSSEES - BOURNEMOUTH UNIVERSITY - BLUESOFT SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA - CABLENET COMMUNICATION SYSTEMS LTD - NODALPOINT SYSTEMS - - - EUR 1 611 000 - - - Intelligence-Driven Urban Internet-of-Things Ecosystems for Trustworthy and Circular Smart Cities - - - EUR 1 611 000 - - - Greece - France - United Kingdom - Poland - Cyprus - Greece - - - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - IDEAL-CITIES aims to develop, demonstrate and evaluate an open modular platform for building adaptive Internet-of-Things and Participatory Sensing (IoTPS) based Smart City applications, supported by Big Data analytics and - Cloud services. IDEAL-CITIES outcomes will increase urban life quality, safety and inclusivity by enabling citizens and authorities to produce and exchange contextualised distributed intelligence and information in real-time, in a trustworthy and - sustainable manner. The IDEAL-CITIES platform will foster the development and uptake of novel IoTPS-based Smart City applications and enhance the associated market base, by demonstrating new feasible ways for providing IoTPS applications and services - which can contribute to urban citizen’s well-being and the cities’ circular economy. The IDEAL-CITIES platform will be demonstrated in the context of two fully-fledged IoTPS Applications, with a focus on mobility for the impaired and on citizen - safety, in close cooperation with involved communities (a non-profit organisation for the blind and partially-sighted and four municipalities, respectively), validating the utility of the proposed platform and approach. - - 2022-06-30, Grant Agreement signed - - - 2018-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Greece - - - IDEAL-CITIES - - - H2020-MSCA-RISE-2017 - - - 778229 - - - - - AGRICULTURAL UNIVERSITY OF ATHENS - UNIVERSITA CATTOLICA DEL SACRO CUORE - INSTITUT NATIONAL D'ETUDES SUPERIEURES AGRONOMIQUES DE MONTPELLIER - Q TECHNOLOGIES LTD - KPAD LTD - AGRICULTURAL & ENVIRONMENTAL SOLUTIONS - M2S - NEUROPUBLIC AE PLIROFORIKIS & EPIKOINONION - - - EUR 1 183 500 - - - Implementation of integrated and innovative Precision Agriculture management strategies to reduce the occurrence of ochratoxins along the vine value chain products: grapes, raisins/currants and wine - - - EUR 1 183 500 - - - Greece - Italy - France - United Kingdom - United Kingdom - Greece - France - Greece - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The risk of mycotoxins is a global issue that represents a serious risk for human and animal health. Οchratoxin A (OTA) is a very toxic mycotoxin that constitutes a severe problem for viticulture and taking into account the - extreme climatic events that are frequently faced in recent years, the OTA problem is arising in wine and raisins/currants. OchraVine Control project will offer an inexistent innovative, sustainable and integrated smart ICT solution (OchraVine - Control DSS) considering fungal, host and environmental indicators that affect OTA contamination along the vine grape-wine value chain. The OchraVine Control DSS will allow prediction and monitoring at pre- and post-harvest level to control - Aspergillus infection and OTA contamination in vine cultivation by combining epidemiological data, biological and chemical management strategies, post-havrest technologies and precision agriculture tools. OchraVine Control DSS solution will pursue a - field-to-fork approach and will link and translate the information derived from the OchraRisk and OchraDetect predictive map tools and real data obtained during the monitoring controls by the OchraSensor. OchraVine Control DSS tool will be placed in - an open access web platform and in combination with data from the OchraRed Integrated Management Strategy will provide risk prediction information (i.e. geographic OTA vine alerts), practical recommended solutions for OTA management and will verify - the compliance with legislation requirements in a rapid and cost-effective way. The project will have a multi-actor international approach involving 3 RTDs and 5 SMEs that will exchange skills and knowledge and will all have a vital role in the - design of the solutions, implementation, testing, dissemination, communication and economic exploitation. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Greece - - - OchraVine Control - - - H2020-MSCA-RISE-2017 - - - 778219 - - - - - LVIV POLYTECHNIC NATIONAL UNIVERSITY - SMARTMEMBRANES GMBH - POLITECHNIKA CZESTOCHOWSKA - SCIENTIFIC RESEARCH COMPANY CARAT -BRANCH ENTERPRISE OF PJSC CONCERN -ELECTRON - UNIVERSITE D'ANGERS - POLITECHNIKA WARSZAWSKA - PRIVATE ENTERPRISE SOFTPARTNERS - FORSCHUNGSZENTRUM JULICH GMBH - ENERGIA OZE SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA - - - EUR 1 692 000 - - - Innovative Optical/Quasioptical Technologies and Nano Engineering of Anisotropic Materials for Creating Active Cells with Substantially Improved Energy Efficiency - - - EUR 1 692 000 - - - Ukraine - Germany - Poland - Ukraine - France - Poland - Ukraine - Germany - Poland - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The principal goal of the project is to combine research expertise in optics, crystallography and material science with efforts in material engineering to go beyond state-of-the-art in the development of highly efficient - energy saving optical cells based on electro-, acousto- and nonlinear optical effects and designed to operate in optical and quasi-optical (sub-THz) ranges. - - 2022-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Ukraine - - - IMAGE - - - H2020-MSCA-RISE-2017 - - - 778156 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 499 875 - - - Nanoparticles as Partners in Frustrated Lewis Pairs: Boosting the Surface Reactivity of Inorganic Nanoparticles - - - EUR 1 499 875 - - - France - France - - - Research Organisations - Research Organisations - - Associating bulky and strong Lewis acid and base creates a Frustrated Lewis Pair (FLP). Traditionally, both FLP partners are molecules. Molecular FLPs have shown excellent abilities to catch and dissociate small molecules such - as H2 in a heterolytic way, under mild conditions. The driving force is the destabilization of the initial acid-base adduct, sterically frustrated: it liberates a reactive pocket that catches the small molecule guest, and strongly lowers the - activation energy for bond dissociation. - - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - NanoFLP - - - ERC-2017-STG - - - 758480 - - - - - LATVIJAS UNIVERSITATE - VILNIAUS UNIVERSITETAS - ECOLE NATIONALE SUPERIEURE DE CHIMIE DE MONTPELLIER - UNIWERSYTET IM. ADAMA MICKIEWICZA W POZNANIU - FONDAZIONE BRUNO KESSLER - EESTI MATERJALITEHNOLOOGIATE ARENDUSKESKUSE AS - BIOSENSOR S.R.L. - NANOPHARMA AS - Institute of Biophysics and Cell Engineering, National Academy of Sciences of Belarus - - - EUR 1 282 500 - - - Novel 1D photonic metal oxide nanostructures for early stage cancer detection - - - EUR 1 282 500 - - - Latvia - Lithuania - France - Poland - Italy - Estonia - Italy - Czech Republic - Belarus - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - - The project CanBioSe targeted to strengthen international and intersectoral collaboration, sharing new ideas and knowledge transfer from research to market and vice versa in the field of nanostructured metal oxide optical - biosensors for cancer cells detection. Interdisciplinary project research and innovation goals are targeted to develop a new portable tool for early stage cancer detection which can solve on of important health challenges in EU society. One - dimensional (1D) polimer nanofibers will be deposited by electrospinning technique. Photonic nanomaterials, based on metal oxide based nanostructures (ZnO, ZnO/Al2O3 nanolaminates, Au/ZnO and ZnO/Au) will coat the 1D nanofibers. Metal oxides and Au - nanoparticles will be deposited with Atomic Layer Deposition (ALD) and electrophoresis, respectively. Bioselective layer will be formed by immobilization of specific antibodies on the biosensor surface. Photoluminescence and optical spectroscopy will - be used for recording of the biosensor signal. Biosensor testing will be performed on cancer cells (human chronic lymphocyte leukemia (CLL) leucosis and acute lymphoblastic leucosis). The biosensor will be integrated with microfluidic system in order - to minimize dimensions and simplify the use of the detection system. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Latvia - - - CanBioSe - - - H2020-MSCA-RISE-2017 - - - 778157 - - - - - BRUNEL UNIVERSITY LONDON - BRUNEL UNIVERSITY LONDON - - - EUR 1 407 675,63 - - - Refiguring Conservation in/for 'the Anthropocene': The Global Lives of the Orangutan - - - EUR 1 407 675,63 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In recent years, conservationists have engaged in heated debates about whether and how conservation should respond to the challenges posed by ‘the Anthropocene’—a term increasingly used to encapsulate the overwhelming, - transformative impact of human activity on the Earth system. How are these debates—and the wider ‘Anthropocenic’ awareness they embody—reshaping conservation philosophy, strategy and practice? How are they manifested in and across diverse contexts? - How, conversely, are global conservation developments and ‘Anthropocenic’ phenomena apprehended and reshaped on the ground? This project explores such urgent questions through an unprecedented study of the global nexus of orangutan conservation at a - unique historical juncture marked by flux and uncertainty. Combining in-depth ethnography and multiply-scaled cross-cultural comparison, it approaches orangutan conservation as a sprawling, uneven terrain across which the rapidly-evolving - relationship between conservation and ‘the Anthropocene’ is being played out. Its objectives are 1) to examine if and how contemporary conservation is being ‘scaled up’ and re(con)figured in and for ‘the Anthropocene’; and 2) to cut ‘the - Anthropocene’ down to size by exploring how it is experienced, conceptualized, contested or indeed refused across multiple conservation settings. Comprising four interlinked studies to be carried out simultaneously at the main nodes of orangutan - conservation, this project seeks to pioneer a new synchronic, multi-sited approach to the analysis of global conservation and lay the groundwork for an empirically-driven, theoretically ambitious new field of scholarship on conservation in/for ‘the - Anthropocene’—one that will revitalize social scientific understandings of conservation while adding much-needed empirical depth and nuance to emerging cross-disciplinary discussions about ‘the Anthropocene’. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - GLO - - - ERC-2017-STG - - - 758494 - - - - - UNIVERSITE DE STRASBOURG - UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA - UNIVERSITA DEGLI STUDI DI PARMA - NANOMOL TECHNOLOGIES SA - ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING MCGILL UNIVERSITY - UNIVERSIDAD DE LA HABANA - THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - - - EUR 598 500 - - - Hybrid Nanostructured Oligonucleotide Platforms for Biomedical Applications - - - EUR 598 500 - - - France - Italy - Italy - Spain - Canada - Cuba - United States - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Nanotechnology has received widespread attention in the last several decades due to the technological breakthroughs it has enabled across sectors from electronics to medicine. Towards the great challenges that nanotechnology - arise, Nano-OligoMed has the ambition to establish and support a network of international collaboration, enabling a collaborative scientific team to effectively use a diversity of approaches and strategies to generate and test hybrid nanomaterials - for the efficient and safe systemic delivery of oligonucleotide-based therapeutic agents. To this end, we have set-up a joint multidisciplinary scientific collaborative programme that through exchange, international mobility, and strongly - collaborative transfer of knowledge and training activities between 4 European and 3 extra-European countries, will bring together leading experts under the field of “nanomaterials in biomedicine”. The scientific aim of Nano-OligoMed is the creation - of degradable hybrid structures that combine the rigid, inert silica with the delicate programmable oligonucleotides or artificial oligonucleotide-mimics. The possibility to develop novel oligonucleotide-based materials will enable a) the degradation - of the drug carrier at the presence of a specific input as a function of the intrinsic bio-responsive feature of oligonucleotides, b) the activation of a therapeutic function as a result of the bio-molecular interaction between the - oligonucleotide-based material and the molecular target (i.e. miRNAs) and c) the delivery of the chemical payload (DNA and/or artificial mimics, even in combination with cancer drugs) upon cell internalization. The international academic networking, - the broadening of the research skills, the educational activities, will provide to young (PhD students) and senior scientists, specific competences in the field of materials sciences, nanotechnology, molecular biology and molecular medicine. - - 2021-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - France - - - Nano-OligoMed - - - H2020-MSCA-RISE-2017 - - - 778133 - - - - - SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI DI TRIESTE - SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI DI TRIESTE - - - EUR 1 055 317 - - - Atomic Gauge and Entanglement Theories - - - EUR 1 055 317 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - AGEnTh is an interdisciplinary proposal which aims at theoretically investigating atomic many-body systems (cold atoms and trapped ions) in close connection to concepts from quantum information, condensed matter, and high - energy physics. The main goals of this programme are to: - - 2023-04-30, Grant Agreement signed - - - 2018-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Italy - - - AGEnTh - - - ERC-2017-STG - - - 758329 - - - - - NARODNE POL'NOHOSPODARSKE A POTRAVINARSKE CENTRUM - INOCURE SRO - IGV GREENFOOD GGMBH - NUTRITION SCIENCES NV - AGRICULTURAL UNIVERSITY OF ATHENS - BIO BASE EUROPE PILOT PLANT VZW - SELCUK UNIVERSITESI - VETERINAERMEDIZINISCHE UNIVERSITAET WIEN - - - EUR 733 500 - - - Nanostructured carriers for improved cattle feed - - - EUR 733 500 - - - Slovakia - Czech Republic - Germany - Belgium - Greece - Belgium - Turkey - Austria - - - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Other - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The project focuses on a highly actual problem of productivity and quality of livestock production. Livestock production is essential for a sustainable and self-sufficient manufacturing of wide range of products in food - industry. One of the key strategies how to enhance competitiveness in the area of food industry is to increase the efficiency of stock raising. Nutritional deficiencies are key factors reducing the efficiency of stock raising, due to high prevalence - of serious diseases. Maintaining optimal health of cattle is a key factor for increasing the efficiency of livestock. NanoFEED responds to this factors by nano/microencapsulation approach to advanced core/shell particles with pH sensitive - properties.The proposed technology enables encapsulation of diverse active molecules and simplify the protection against degradation in rumen for wide range of active molecules. Nevertheless, due to encapsulation and improved delivery to small - intestine, novel active molecules may be used to treat nutritional deficiencies. The process of encapsulation is based on green and biobased methods with minimal carbon footprint helping in development of sustainable bioeconomy. The results of - NanoFEED will improve the cattle life expectation, quality of food and will promote more competitive livestock production. - - 2022-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Slovakia - - - NanoFEED - - - H2020-MSCA-RISE-2017 - - - 778098 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 499 375 - - - The missing link between Perception and Cognition: The case of multiple-person scenarios - - - EUR 1 499 375 - - - France - France - - - Research Organisations - Research Organisations - - Seeing persons among other persons interacting with each other and trying to understand what is happening is a fundamental task for our daily life. How the brain manifests the representational and integrative capacity - necessary for this function is beyond our current understanding. THEMPO sees in the study of multiple-person scenarios an opportunity to address how human cognition deals with real-word social interactions and, more generally, how the information - process is devised to go from a perceptual representation of entities (e.g. bodies) to a representation of the abstract relations that pull those entities together into a structured unit (i.e. a social event). Multiple-person scenarios are thus a - case study to address the missing link between perception and higher cognition, and to understand how early visual perceptual representations make contact with relational/symbolic representations. THEMPO will pursue different levels of explanation, - defining the sequence of information-processing stages involved, and their implementation in the brain in terms of large-scale network organization (functional, causal and hierarchical relations among perceptual and non-perceptual neural processes). - It will further study the neural (linear and/or nonlinear) operations to transform perceptual information along the way toward abstraction. This will be accomplished by combining fine cognitive manipulations, imaging and neurostimulation techniques - (fMRI, TMS), and advanced analytical approaches based on multivariate analyses of neural response patterns to define the operations behind neural activity in humans. THEMPO will culminate in the formulation of a model that will serve as a test bed to - address individual variations in perceptual and neural combinatorial operations and, possibly, uncover the roots of altered social cognition. THEMPO is designed to build upon itself, from relatively simple stages to high-risk, high-gain objectives, - as a safeguard to success. - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - THEMPO - - - ERC-2017-STG - - - 758473 - - - - - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - - - EUR 1 499 350 - - - Chromosomal domain formation, compartmentalization and architecture - - - EUR 1 499 350 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The three-dimensional organization of chromosomes is necessary for hereditary fidelity and gene regulation. Recent studies have found that eukaryotic interphase chromosomes are spatially organized in compartments, chiefly - topologically associated domains (TADs), in a hierarchical order of nested chromatin loops, coining the term “chromosome folding”. TADs are clusters of genes and regulatory elements that are confined to their genomic compartment by spatially - constricting their accessible range of action. The folded structure of chromosomes through long-range loops enables mutual interactions of distant genomic loci that otherwise would not be in contact. - - 2023-06-30, Grant Agreement signed - - - 2018-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - CHROMDOM - - - ERC-2017-STG - - - 758124 - - - - - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - - - EUR 1 499 250 - - - Pyrazine Signalling in Commensal and Pathogenic Bacteria - - - EUR 1 499 250 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Quorum sensing (QS) is a bacterial cell–cell communication process involving the production, release, and detection of extracellular signal molecules called autoinducers. QS is key to all microbiology as it enables otherwise - solitary bacteria to coordinate complex cooperative tasks such as biofilm formation and pathogenesis. Consequently, targeting QS is a promising new concept for antimicrobial therapy. However, for this concept to become reality, we must first identify - QS systems in pathogenic bacteria, discover the relevant autoinducers and study the underlying regulatory principles. - - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - PyraSig - - - ERC-2017-STG - - - 758212 - - - - - TECHNISCHE UNIVERSITEIT DELFT - TECHNISCHE UNIVERSITEIT DELFT - - - EUR 1 500 000 - - - A combined in vitro and in vivo approach to dissect biochemical network evolution. - - - EUR 1 500 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - How do organisms evolve? I propose to study how biochemical networks reorganize during evolution without compromising fitness. This is a complex problem: firstly, it is hard to know if a mutation increased fitness because this - depends on the environment it arose in, which is typically unknown. Secondly, it is hard to find out how adaptive mutations improve fitness, because in cells, all biochemical networks are connected. I will reduce the complexity by two approaches, - focused on symmetry-breaking in budding yeast, a functionally conserved process, which is the first step for polarity establishment and essential for proliferation. - - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - EvoCellBio - - - ERC-2017-STG - - - 758132 - - - - - KOBENHAVNS UNIVERSITET - KOBENHAVNS UNIVERSITET - STOCKHOLMS UNIVERSITET - - - EUR 1 499 531 - - - Effects of Prenatal Exposure to Acrylamide on Health: Prospective Biomarker-Based Studies - - - EUR 1 499 531 - - - Denmark - Denmark - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Background: Acrylamide is a chemical formed in many commonly consumed foods and beverages. It is neurotoxic, crosses the placenta and has been associated with restriction of fetal growth in humans. In animals, acrylamide - causes heritable mutations, tumors, developmental toxicity, reduced fertility and impaired growth. Therefore, the discovery of acrylamide in food in 2002 raised concern about human health effects worldwide. Still, epidemiological studies are limited - and effects on health of prenatal exposure have never been evaluated. - - - 2023-06-30, Grant Agreement signed - - - 2018-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Denmark - - - CHIPS - - - ERC-2017-STG - - - 758151 - - - - - INSTITUT CURIE - INSTITUT CURIE - - - EUR 1 500 000 - - - Microsatellite Barcoding: reconstructing the family tree of hematopoietic cells - - - EUR 1 500 000 - - - France - France - - - Research Organisations - Research Organisations - - While murine hematopoiesis has been considered as resolved science, recent results using barcoding, which allows the tracing of single cells in vivo, clearly show that the topology of the murine hematopoietic tree needs - revisions. In parallel, human hematopoiesis has been overlooked and is widely considered as following the same tree as in mice. To leverage our understanding of normal human hematopoiesis, tools for barcoding in humans are urgently needed. This - research program seeks to meet this need by taking advantage of recent developments in next generation sequencing to provide an improved barcoding method for in vivo use in human. Our microsatellite barcoding method exploits the fact that - microsatellites in various loci undergo length changes during cell division, to create a natural barcode for each cell, and reconstruct the overall differentiation tree using a phylogenetic algorithm. Our technique, which is highly detailed with - respect to current versions of microsatellite barcoding, provides high dimensional characterization of the cells and will allow the inference of important properties such as new phenotypic markers and key molecular regulators. Therefore, we will - provide insights into both cell lineage and the molecular mechanisms involved in differentiation. With this method, we will provide the first in vivo description of the human hematopoietic tree and identify new progenitors and key molecular factors - involved in human hematopoiesis. This knowledge will allow us to test whether cells with different origins have different functions, a key question in immunology in particular during infection and inflammation, and it will help design ways of - therapeutically manipulating the hematopoietic system. More generally it will impact our understanding of stem cell differentiation for which hematopoiesis is used as an exemplar. - - 2023-07-31, Grant Agreement signed - - - 2018-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - MicroBar - - - ERC-2017-STG - - - 758170 - - - - - UNIVERSITETET I OSLO - UNIVERSITETET I OSLO - - - EUR 1 500 000 - - - Mixed-phase clouds and climate (MC2) – from process-level understanding to large-scale impacts - - - EUR 1 500 000 - - - Norway - Norway - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The importance of mixed-phase clouds (i.e. clouds in which liquid and ice may co-exist) for weather and climate has become increasingly evident in recent years. We now know that a majority of the precipitation reaching Earth’s - surface originates from mixed-phase clouds, and the way cloud phase changes under global warming has emerged as a critically important climate feedback. Atmospheric aerosols may also have affected climate via mixed-phase clouds, but the magnitude and - even sign of this effect is currently unknown. Satellite observations have recently revealed that cloud phase is misrepresented in global climate models (GCMs), suggesting systematic GCM biases in precipitation formation and cloud-climate feedbacks. - Such biases give us reason to doubt GCM projections of the climate response to CO2 increases, or to changing atmospheric aerosol loadings. This proposal seeks to address the above issues, through a multi-angle and multi-tool approach: (i) By - conducting field measurements of cloud phase at mid- and high latitudes, we seek to identify the small-scale structure of mixed-phase clouds. (ii) Large-eddy simulations will then be employed to identify the underlying physics responsible for the - observed structures, and the field measurements will provide case studies for regional cloud-resolving modelling in order to test and revise state-of-the-art cloud microphysics parameterizations. (iii) GCMs, with revised microphysics - parameterizations, will be confronted with cloud phase constraints available from space. (iv) Finally, the same GCMs will be used to re-evaluate the climate impact of mixed-phase clouds in terms of their contribution to climate forcings and - feedbacks. Through this synergistic combination of tools for a multi-scale study of mixed-phase clouds, the proposed research has the potential to bring the field of climate science forward, from improved process-level understanding at small scales, - to better climate change predictions on the global scale. - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Norway - - - MC2 - - - ERC-2017-STG - - - 758005 - - - - - UNIVERSITAT AUTONOMA DE BARCELONA - UNIVERSITAT AUTONOMA DE BARCELONA - - - EUR 1 418 869 - - - Paradoxes and Metaphors of Time in Early Universe(s) - - - EUR 1 418 869 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - PROTEUS studies main strategies devised by Western philosophy in representing time in cosmology. It aims at modifying current metaphysics and its relationship with cosmology in the light of recent scientific debates in quantum - gravity and quantum cosmology, thereby boosting a new research field in history and philosophy of cosmology. The project is based on two hypotheses: 1) the history of philosophy reveals a guideline that can be traced back to Plato and that - characterizes physical and metaphysical approaches to the question of the beginning of the universe in terms of a tension between fundamentality and non-fundamentality of time; 2) there is a conceptual problematic assumption in Western culture and it - consists in shaping the problem of the origin of the world as a problem of thinking about the very same conditions of possibility of the origin of a process that is not in time. The project spells out the conceptual roots of current representations - of time in quantum gravity and quantum cosmology and highlights the conceptual break that they provide with respect to philosophical concepts of time portrayed in previous systems. PROTEUS explores in detail the notions of time and the paradoxes - emerging in the philosophy and cosmology of Plato and Kant and identifies the fundamental characters of emergent time in current quantum gravity theories. In identifying these fundamental features, PROTEUS produces conceptual innovation in - metaphysics in such a way that philosophical investigation is complementary to the development of current theories. PROTEUS elaborates alternative argument(s) to anthropic principle, as well as new categories accounting for the notion of ‘contingent - necessity’ of the world. The research team includes members from different backgrounds (philosophy, mathematics and physics) and will promote the application of a new methodology emphasizing the relevance of the history of philosophy and the actual - interaction between philosophers and scientists. - - 2023-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Spain - - - PROTEUS - - - ERC-2017-STG - - - 758145 - - - - - UNIVERSITAT WIEN - UNIVERSITAT WIEN - - - EUR 1 257 973 - - - Islamic architecture and Orientalizing style in Habsburg Bosnia, 1878-1918 - - - EUR 1 257 973 - - - Austria - Austria - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The project highlights a grossly understudied experiment at the intersection of nineteenth-century European and Islamic architectural histories. It draws attention to a significant body of buildings designed by architects - trained in Central Europe for use by Muslims in Habsburg-ruled Bosnia-Herzegovina (1878-1918). These buildings, many of which mosques, largely draw upon a traditional Islamic formal and functional typology. The composition and decoration of their - facades, however, is the product of nineteenth-century Historicist conduct. Quoted are elements from assorted Islamic artistic heritages, with prominence given to Cairo and Andalusia. In Bosnia, many of these buildings were misinterpreted as mere - renovations of Ottoman edifices, as is indeed declared on several inscriptions. However, this information generally appears to pertain to the institutions accommodated in these buildings rather than to their present form and architecture. - - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Austria - - - THEKAISERSMOSQUES - - - ERC-2017-STG - - - 758099 - - - - - KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN - KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN - - - EUR 1 490 529 - - - A molecular approach to treat diabetes mellitus onset dependent coronaropathy - - - EUR 1 490 529 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In Europe, 59 million patients suffer from diabetes mellitus with health costs of 142 billion Euros per year. As one of the most challenging consequences, diabetes inflicts cardiovascular disease leading to cardiomyopathy and - cardiac death. A global, current aim lies in preventing cardiac complications in patients with diabetes mellitus. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - DIAMONDCOR - - - ERC-2017-STG - - - 758087 - - - - - UNIVERSITAET KLAGENFURT - UNIVERSITAET KLAGENFURT - - - EUR 1 401 941 - - - Hidden Emissions of Forest Transitions: GHG effects of socio-metabolic processes reducingpressures on forests - - - EUR 1 401 941 - - - Austria - Austria - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - A forest transition, i.e. forest expansion after a long period of deforestation, has occurred in many, mostly industrialized countries. Forest transitions have recently resulted in declining rates of global net deforestation - and contributed to carbon (C) sinks in terrestrial ecosystems. Studies have shown the concurrence of forest transitions and industrialization processes, but the systemic links between forest transitions, their underlying socio-metabolic processes and - associated greenhouse gas (GHG) emissions have been neither systematically explored nor quantified. - - 2023-03-31, Grant Agreement signed - - - 2018-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Austria - - - HEFT - - - ERC-2017-STG - - - 757995 - - - - - THE UNIVERSITY OF MANCHESTER - THE UNIVERSITY OF MANCHESTER - - - EUR 1 492 424 - - - Creating Versatile Metallo-Enzyme Environments for Selective C-H Activation Chemistry: Lignocellulose Deconstruction and Beyond - - - EUR 1 492 424 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The availability of a versatile catalytic platform to precisely target and functionalize individual C-H bonds in complex organic molecules would revolutionize our synthetic strategies, leading to streamlined routes to high - value chemicals and supporting the development of a ‘greener’ chemical industry. Although an impressive range of C-H functionalizations can be achieved with small transition metal complexes, site selectivity is often determined by features of the - substrate, and not by the catalyst. A general approach to achieve the more aspirational ‘catalyst controlled’ transformations requires molecular recognition elements within the catalyst which: a) allow precise substrate orientation and b) can be - tuned to alter selectivity. In principle, these requirements could be perfectly addressed by protein catalysts which can be readily adapted via laboratory evolution. However, enzyme engineering strategies are currently limited to Nature’s twenty - amino acid alphabet, severely limiting the range of metal co-ordination environments, and thus catalytic activities, that are accessible within proteins. - - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - enzC-Hem - - - ERC-2017-STG - - - 757991 - - - - - PANEPISTIMIO THESSALIAS - UNIVERSIDADE DO PORTO - CENTRO DE ESTUDIOS SUPERIORES DE LA INDUSTRIA FARMACEUTICA SA - CHRISTOS PAPADOPOULOS & SIA O.E. - - - EUR 828 000 - - - Nutraceutical supplementation based on colostrum for prevention of osteoporosis - - - EUR 828 000 - - - Greece - Portugal - Spain - Greece - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Osteoporosis constitutes a major public health concern. The economic burden of osteoporotic fractures in EU is expected to increase 25% by 2025 compared to 2010. These estimates may indicate an inefficiency of current drugs - for osteoporosis. Actually, the use of pharmacological agents for osteoporosis has been decreasing in EU, probably due to the reported side effects. Therefore, there is a need for innovative agents to reduce the burden of osteoporosis. Colostrum is a - promising agent against bone loss since it has natural constituents that are directly involved in bone metabolism. As a nutraceutical, colostrum confers an advantage over pharmacological drugs since it can avoid side effects. However, the possibility - of its use as a nutraceutical agent for osteoporosis have only received attention within the scientific community. The knowledge produced on the effects of colostrum on bone metabolism has not yet been transferred to the market because academic - institutions lack on expertise to create a new product. On the other hand, industry has knowledge on product development, but lack expertise on research skills. In accordance, what hinders the creation of an innovative product based on colostrum for - prevention of osteoporosis is the absence of an intersectorial collaboration. As consequence, there is a clearly gap between research on the matter and its application. COLOSTEO aims to fill in this gap by creating an intersectorial collaboration to - exchange knowledge and expertise towards the creation of an innovative nutraceutical product based on colostrum to prevent osteoporosis. This aim will be achieved by bridging two academic with two industrial institutions that through intersectorial - secondments will exchange knowledge, ideas and expertise towards the creation of an innovative nutraceutical product based on colostrum to prevent osteoporosis. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Greece - - - COLOSTEO - - - H2020-MSCA-RISE-2017 - - - 778277 - - - - - KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN - KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN - - - EUR 1 499 989 - - - Deconstruction of a neural circuit for working memory: hubs, coding mechanisms, and signal routing - - - EUR 1 499 989 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Working memory is the basis of cognition. It allows behaviour to be governed by internal goals rather than by reflexive stimulus-response mappings. The neural mechanisms of memory maintenance are heavily contested. Animal - electrophysiology studies suggest a pivotal role of persistent spiking activity in single neurons of the prefrontal cortex, whereas human neuroimaging points to sub-threshold synaptic activity distributed across sensory cortex. This double - dissociation of storage mechanisms and storage sites could result from the comparison of different recording methods, which measure distinct neuronal signals. Alternatively, there might be a fundamental difference between humans and animals. My key - objective is to formulate general principles of working memory coding at the cellular and circuit level by integrating across previously disconnected lines of research. I will address two central questions. First, where and how is the memorized - information stored? I will use an innovative approach to record large-scale single-unit activity from a cognitive (prefrontal) and a sensory (auditory) region in awake neurosurgical patients and directly compare the data to recordings from mice - performing the same auditory working memory task. This will allow me to determine whether the mnemonic fingerprints are species-specific or shared across humans and rodents. Second, what neural pathways support the flow of information during working - memory? Using the animal model, I will disrupt cross-regional interactions in the memory network with millisecond-precise, projection-specific optogenetic tools in order to dissect the contribution of each hub to memory storage and memory access. - This project provides an unprecedented one-to-one matching of behavioural tasks and recording methods with single-cell and split-second resolution in humans and rodents. It represents a major step forward in understanding the cellular and circuit - basis of a critical cognitive brain function. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - MEMCIRCUIT - - - ERC-2017-STG - - - 758032 - - - - - OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN - OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN - - - EUR 1 499 992 - - - ‘Challenging Time(s)’ – A New Approach to Written Sources for Ancient Egyptian Chronology - - - EUR 1 499 992 - - - Austria - Austria - - - Research Organisations - Research Organisations - - The chronology of ancient Egypt is a golden thread for the memory of early civilisation. It is not only the scaffolding of four millennia of Egyptian history, but also one of the pillars of the chronology of the entire ancient - Near East and eastern Mediterranean. The basic division of Egyptian history into 31 dynasties was introduced by Manetho, an Egyptian historian (c. 280 BC) writing in Greek for the Ptolemaic kings. Despite the fact that this scheme was adopted by - Egyptologists 200 years ago and remains in use until today, there has never been an in-depth analysis of Manetho’s kinglist and of the names in it. Until now, identifying the Greek renderings of royal names with their hieroglyphic counterparts was - more or less educated guesswork. It is thus essential to introduce the principles of textual criticism, to evaluate royal names on a firm linguistic basis and to provide for the first time ever an Egyptological commentary on Manetho’s kinglist. Just - like Manetho did long ago, now it is necessary to gather all inscriptional evidence on Egyptian history: dated inscriptions, biographic and prosopographic data of royalty and commoners, genuine Egyptian kinglists and annals. These data must be - critically evaluated in context, their assignment to specific reigns must be reconsidered, and genealogies and sequences of officials must be reviewed. The results are not only important for Egyptian historical chronology and for our understanding of - the Egyptian perception of history, but also for the interpretation of chronological data gained from archaeological excavations (material culture) and sciences (14C dates, which are interpreted on the basis of historical chronology, e.g., via - ‘Bayesian modelling’). The applicant has already shown the significance of this approach in pilot studies on the pyramid age. Further work in cooperation with international specialists will thus shed new light on ancient sources in order to determine - the chronology of early civilisation. - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Austria - - - CT - - - ERC-2017-STG - - - 757951 - - - - - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - - - EUR 1 500 000 - - - Atmospheres across the Universe - - - EUR 1 500 000 - - - France - France - - - Research Organisations - Research Organisations - - Which molecules are present in the atmosphere of exoplanets? What are their mass, radius and age? Do they have clouds, convection (atmospheric turbulence), fingering convection, or a circulation induced by irradiation? These - questions are fundamental in exoplanetology in order to study issues such as planet formation and exoplanet habitability. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - ATMO - - - ERC-2017-STG - - - 757858 - - - - - TECHNISCHE UNIVERSITEIT EINDHOVEN - TECHNISCHE UNIVERSITEIT EINDHOVEN - - - EUR 1 998 504,75 - - - Multi-perspective Ultrasound Strain Imaging & Elastography - - - EUR 1 998 504,75 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Ultrasound (US) is the modality of choice for imaging and functional measurements of the cardiovascular system due to its high spatial and temporal resolution. In recent years, the use of US has been on the rise owing to huge - advancements in acquisition speed and resolution. Nevertheless, because of physical constraints, several issues —limited field-of-view, refraction, resolution and, contrast anisotropy— cannot be resolved using a single probe. - - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - MUSE - - - ERC-2017-STG - - - 757958 - - - - - KAROLINSKA INSTITUTET - KAROLINSKA INSTITUTET - - - EUR 1 500 000 - - - A TRranslational approach to Identify Biomarkers for Asthma and Lung function impairment - - - EUR 1 500 000 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Asthma is a chronic inflammatory disease of the airways that cause symptoms like wheezing and breathlessness. In children, asthma is the most common chronic disease and according to the WHO, more than 300 million people are - affected globally. There is no curative treatment available. Persistence of childhood asthma into adult life is associated with lung function impairment and increased risk of chronic obstructive pulmonary disease, COPD. Evidence is now emerging that - adult diseases, like COPD, may have their origin early in life. However, there are no established biomarkers that can accurately monitor asthma progression or predict development of COPD in adults. In this TRIBAL project, I will capitalize on rich - longitudinal data and repeated bio-sampling from the Swedish BAMSE study, a world-leading population-based birth cohort of 4,089 participants with a new 24-year follow-up starting in 2017. A key aim with the new follow-up is to identify young adults - in their 20s with persistent asthma and pre-stage COPD by advanced lung function assessment that includes bronchodilator and nitrogen washout tests. In TRIBAL, the unique setup is deep phenotyping of these patients describing different aspects of the - respiratory system, as well as molecular characteristics of relevant bio-samples and cells. Disease-related biomarkers and involved mechanisms, from gene to protein, will be identified from early childhood to adulthood. Both the innate and the - adapted immune system with detailed cell characterization will be explored in relation to exposure and disease development. Specifically, with this novel approach I will address the time point during childhood when disease processes related to - persistent asthma and pre-stage COPD were initiated. The ultimate goal in TRIBAL is to provide new knowledge for targeted preventive efforts in children at risk of adult chronic lung disease, and to identify potential targets for new asthma and COPD - drugs. - - 2022-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Sweden - - - TRIBAL - - - ERC-2017-STG - - - 757919 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 436 330 - - - SOot in TUrbulent Flames: a new look at soot production processes in turbulent flames leading to novel models for predictive large eddy simulations - - - EUR 1 436 330 - - - France - France - - - Research Organisations - Research Organisations - - Many practical systems emit soot into the atmosphere as a result of incomplete combustion of hydrocarbons. This pollutant emission is characterized by a distribution of solid carbon particles with different sizes and shapes, - which have negative effects on human health and environment. Controlling such emission represents a societal issue and an industrial challenge that require a deep understanding of the intricate processes underlying soot production in the turbulent - flames that generally characterize practical systems. In this context, progress in numerical simulations is essential to the successful design of low-emission combustion systems. Unfortunately, the Large-Eddy Simultations (LES) approach, which has - successfully demonstrated its capacity to represent gaseous turbulent combustion processes, is far from being predictive for soot emission. Indeed, soot production in turbulent flames is a complex process which is not easy to be represented with the - classical LES strategy: the long time scales and the broad range of length scales place soot processes outside the usual scale ranges of LES subgrid models. In this context, the goal of the present project is to provide new insights on the processes - governing soot production in turbulent flames to develop novel LES models, encompassing the state-of-art and allowing reliable predictions of soot in turbulent flames. These objectives will be achieved by: (1) characterizing the turbulence-flame-soot - coupling from novel well-controlled experiments employing advanced space and time resolved optical diagnostics; (2) developing new subgrid models based on information extracted from experiments and high-fidelity simulations; (3) validating and - applying the developed LES modeling strategy on complex systems. The research results are expected to drastically improve the prediction of soot production in industrial configurations, helping to design new low-emission systems with notably reduced - soot levels. - - 2023-05-31, Grant Agreement signed - - - 2018-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - SOTUF - - - ERC-2017-STG - - - 757912 - - - - - CENTRE INTERNATIONAL DE RECHERCHE AUX FRONTIERES DE LA CHIMIE - CENTRE INTERNATIONAL DE RECHERCHE AUX FRONTIERES DE LA CHIMIE - - - EUR 1 762 488 - - - Life-like Supramolecular Materials based on Reaction Cycles with Designed Feedback - - - EUR 1 762 488 - - - France - France - - - Research Organisations - Research Organisations - - This “Life-Cycle” ERC proposal aims to develop a new class of artificial supramolecular materials that are kept in sustained non-equilibrium states by continuous dissipation of chemical fuels. Supramolecular polymers in - current artificial materials stick together through weak reversible bonds that can be exchange by thermal energy. In contrast, natural supramolecular polymers such as those in the cytoskeletal network use chemical fuels such as adenosine triphosphate - (ATP) to achieve an incredible adaptivity, motility, growth, and response to external inputs. Development of chemically fueled artificial supramolecular polymers should therefore lead to more life-like materials that could perform functions so far - reserved only for living beings. - - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - Life-Cycle - - - ERC-2017-STG - - - 757910 - - - - - KOBENHAVNS UNIVERSITET - KOBENHAVNS UNIVERSITET - - - EUR 1 427 741 - - - Eco-physiological tradeoffs with crop domestication: have farming ants cracked the code? - - - EUR 1 427 741 - - - Denmark - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Domesticated crops hardly resemble their wild ancestors, and often trade higher yield in artificially optimized conditions for lower performance in fluctuating environments. Leafcutter ants (genus Atta) provide fascinating - parallels with human farmers, harvesting fresh vegetation used as compost to produce domesticated fungal crops that feed massive societies with millions of workers. However, while human agricultural systems are imperiled by rapid global changes, - leafcutter ants have managed to grow one type of cultivar from Texas to Argentina, thriving across extreme rainfall and temperature gradients and across diverse climates over millions of years. However, the eco-physiological mechanisms governing this - farming resiliency are poorly understood. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Denmark - - - ELEVATE - - - ERC-2017-STG - - - 757810 - - - - - UNIVERSITAT POLITECNICA DE CATALUNYA - UNIVERSITAT POLITECNICA DE CATALUNYA - - - EUR 1 100 347,50 - - - Instabilities and homoclinic phenomena in Hamiltonian systems - - - EUR 1 100 347,50 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - A fundamental problem in the study of dynamical systems is to ascertain whether the effect of a perturbation on an integrable Hamiltonian system accumulates over time and leads to a large effect (instability) or it averages - out (stability). Instabilities in nearly integrable systems, usually called Arnold diffusion, take place along resonances and by means of a - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Spain - - - HamInstab - - - ERC-2017-STG - - - 757802 - - - - - INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE - INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE - - - EUR 1 497 045 - - - Accelerating Neuroscience Research by Unifying Knowledge Representation and Analysis Through a Domain Specific Language - - - EUR 1 497 045 - - - France - France - - - Research Organisations - Research Organisations - - Neuroscience is at an inflection point. The 150-year old cortical specialization paradigm, in which cortical brain areas have a distinct set of functions, is experiencing an unprecedented momentum with over 1000 articles being - published every year. However, this paradigm is reaching its limits. Recent studies show that current approaches to atlas brain areas, like relative location, cellular population type, or connectivity, are not enough on their own to characterize a - cortical area and its function unequivocally. This hinders the reproducibility and advancement of neuroscience. - - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - NeuroLang - - - ERC-2017-STG - - - 757672 - - - - - UNIVERSITY COLLEGE LONDON - UNIVERSITY COLLEGE LONDON - - - EUR 1 500 000 - - - The Mechanisms and Dynamics Controlling Cycles of Lymph Node Expansion - - - EUR 1 500 000 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Lymph node swelling is a classical hallmark of immunity. This expansion is observed by doctors, researchers and patients, yet as obvious as this process is, our understanding of the remodelling mechanisms involved are in their - infancy. Lymph node remodelling is rapid and yet completely reversible, occurring countless times throughout our lifetimes. The purpose of this proposal is to understand how lymph node remodelling occurs and is resolved, repeatedly; to understand - immunity in a whole organ context. - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - LNEXPANDS - - - ERC-2017-STG - - - 757573 - - - - - ECOLE NATIONALE DES PONTS ET CHAUSSEES - ECOLE NATIONALE DES PONTS ET CHAUSSEES - - - EUR 1 499 999 - - - Controlling earthQuakes - - - EUR 1 499 999 - - - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - According to the Centre for Research on the Epidemiology of Disasters (CRED), earthquakes are responsible for more than half of the total human losses due to natural disasters from 1994 to 2003. There is no doubt that - earthquakes are lethal and costly. CoQuake proposes an alternative, ground-breaking approach for avoiding catastrophic earthquakes by inducing them at a lower energetic level. Earthquakes are a natural phenomenon that we cannot avoid, but –for the - first time– in CoQuake I will show that it is possible to control them, hence reducing the seismic risk, fatalities and economic cost. CoQuake goes beyond the state-of-the-art by proposing an innovative methodology for investigating the effect and - the controllability of various stimulating techniques that can reactivate seismic faults. It involves large-scale, accurate simulations of fault systems based on constitutive laws derived from micromechanical, grain-by-grain simulations under - Thermo-Hydro-Chemo-Mechanical couplings (THMC), which are not calibrated on the basis of ad-hoc empirical and inaccurate constitutive laws. A pioneer experimental research programme and the design and construction of a new apparatus of metric scale, - will demonstrate CoQuake’s proof-of-principle and it will help to explore the transition from aseismic to seismic slip. CoQuake is an interdisciplinary project as it takes knowledge from various fields of engineering, computational mechanics, - geomechanics, mathematics and geophysics. CoQuake opens a new field and new line of research in earthquake mechanics and engineering, with a direct impact on humanity and science. - - 2023-05-31, Grant Agreement signed - - - 2018-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - CoQuake - - - ERC-2017-STG - - - 757848 - - - - - UNIVERSITE DE LIEGE - UNIVERSITE DE LIEGE - - - EUR 1 499 125 - - - To nap or not to nap? Why napping habits interfere with cognitive fitness in ageing - - - EUR 1 499 125 - - - Belgium - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - All of us know of individuals who remain cognitively sharp at an advanced age. Identifying novel factors which associate with inter-individual variability in -and can be considered protective for- cognitive decline is a - promising area in ageing research. Considering its strong implication in neuroprotective function, COGNAP predicts that variability in circadian rhythmicity explains a significant part of the age-related changes in human cognition. Circadian rhythms - -one of the most fundamental processes of living organisms- are present throughout the nervous system and act on cognitive brain function. Circadian rhythms shape the temporal organization of sleep and wakefulness to achieve human diurnality, - characterized by a consolidated bout of sleep during night-time and a continuous period of wakefulness during the day. Of prime importance is that the temporal organization of sleep and wakefulness evolves throughout the adult lifespan, leading to - higher sleep-wake fragmentation with ageing. The increasing occurrence of daytime napping is the most visible manifestation of this fragmentation. Contrary to the common belief, napping stands as a health risk factor in seniors in epidemiological - data. I posit that chronic napping in older people primarily reflects circadian disruption. Based on my preliminary findings, I predict that this disruption will lead to lower cognitive fitness. I further hypothesise that a re-stabilization of - circadian sleep-wake organization through a nap prevention intervention will reduce age-related cognitive decline. Characterizing the link between cognitive ageing and the temporal distribution of sleep and wakefulness will not only bring - ground-breaking advances at the scientific level, but is also timely in the ageing society. Cognitive decline, as well as inadequately timed sleep, represent dominant determinants of the health span of our fast ageing population and easy - implementable intervention programs are urgently needed. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Belgium - - - COGNAP - - - ERC-2017-STG - - - 757763 - - - - - TECHNISCHE UNIVERSITEIT EINDHOVEN - TECHNISCHE UNIVERSITEIT EINDHOVEN - - - EUR 1 497 982 - - - Fundamentals of the Nonlinear Optical Channel - - - EUR 1 497 982 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Fibre optics are critical infrastructure for society because they carry nearly all the global Internet traffic. For a long time, optical fibre systems were thought to have infinite information-carrying capabilities. With - current traffic demands growing by a factor between 10 and 100 every decade, however, this is no longer the case. In fact, it is currently unknown if the installed optical infrastructure will manage to cope with these demands in the future, or if we - will face the so-called "capacity crunch". - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - FUN-NOTCH - - - ERC-2017-STG - - - 757791 - - - - - THE UNIVERSITY OF EDINBURGH - THE UNIVERSITY OF EDINBURGH - UNIVERSITY COLLEGE LONDON - - - EUR 1 942 471 - - - Tropical Forest Degradation Experiment - - - EUR 1 942 471 - - - United Kingdom - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - We know how to map tropical forest biomass using an array of satellite and aircraft sensors with reasonable accuracy (±15-40 %). However, we do not know how to map biomass change. Simply differencing existing biomass maps - produces noisy and biased results, with confidence intervals unknowable using existing static field plots. Thus the potential for using plentiful free satellite data for biomass change mapping is being wasted. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - FODEX - - - ERC-2017-STG - - - 757526 - - - - - DANMARKS TEKNISKE UNIVERSITET - DANMARKS TEKNISKE UNIVERSITET - - - EUR 1 463 805 - - - Measuring with no tape - - - EUR 1 463 805 - - - Denmark - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Society generates increasing amounts of data, which is both a resource and a challenge. The data reveal new insights that may potentially improve our livelihood, but their quantity renders such insights difficult to find. - Machine learning techniques sift through the data looking for statistical patterns of interest to a given task. Due to an exponential growth in available data, these techniques enable us to automate difficult decisions, such as those needed for - personalized medicine and self-driving cars. - - 2022-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Denmark - - - NoTape - - - ERC-2017-STG - - - 757360 - - - - - UNIVERSITY OF LEEDS - UNIVERSITY OF LEEDS - - - EUR 1 499 840 - - - Data Assimilation for Agent-Based Models: Applications to Civil Emergencies - - - EUR 1 499 840 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Civil emergencies such as flooding, terrorist attacks, fire, etc., can have devastating impacts on people, infrastructure, and economies. Knowing how to best respond to an emergency can be extremely difficult because building - a clear picture of the emerging situation is challenging with the limited data and modelling capabilities that are available. Agent-based modelling (ABM) is a field that excels in its ability to simulate human systems and has therefore become a - popular tool for simulating disasters and for modelling strategies that are aimed at mitigating developing problems. However, the field suffers from a serious drawback: models are not able to incorporate up-to-date data (e.g. social media, mobile - telephone use, public transport records, etc.). Instead they are initialised with historical data and therefore their forecasts diverge rapidly from reality. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - DUST - - - ERC-2017-STG - - - 757455 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 499 901 - - - Structural Biology of Exopolysaccharide Secretion in Bacterial Biofilms - - - EUR 1 499 901 - - - France - France - - - Research Organisations - Research Organisations - - Bacterial biofilm formation is a paramount developmental process in both Gram-positive and Gram-negative species and in many pathogens has been associated with processes of horizontal gene transfer, antibiotic resistance - development and pathogen persistence. Bacterial biofilms are collaborative sessile macrocolonies embedded in complex extracellular matrix that secures both mechanical resistance and a medium for intercellular exchange. - - - 2023-07-31, Grant Agreement signed - - - 2018-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - BioMatrix - - - ERC-2017-STG - - - 757507 - - - - - KARLSRUHER INSTITUT FUER TECHNOLOGIE - KARLSRUHER INSTITUT FUER TECHNOLOGIE - - - EUR 1 499 920 - - - Blood and bone – conjoined twins in health and disease: bone marrow analogs for hematological and musculoskeletal diseases - - - EUR 1 499 920 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Blood and bone are closely intertwined. Their intrinsic regenerative capacities are disturbed in many hematological and musculoskeletal diseases. Re-establishing the regenerative potential is the key to cure these diseases by - regenerative medicine. Multipotent stem cells of both tissues – hematopoietic stem cells (HSCs) for blood and mesenchymal stem/stromal (MSCs) for bone – are the basis for their regenerative capacity. While it is well established that HSCs are - influenced by the bone marrow in their natural environment including MSCs and their progeny, surprisingly little attention has been paid to the reciprocal relationship. The hypothesis of the current proposal is that only when taking both tissues and - their mutual crosstalk into account, we will be able to understand how the regenerative potential of blood and bone is impaired in disease and how it can be re-established with novel treatment strategies. For this purpose we need to understand the - early events of disease onset and progression. Due to the limitations of such studies in human beings and animals, I propose to develop human in vitro models of healthy bone marrow, which can be induced to develop hematological and musculoskeletal - diseases with high incidence, namely leukemia, multiple myeloma and bone metastasis. Previously my team and I developed a simplified bone marrow analog that bases on macroporous, cell-laden biomaterials with tunable physical, biochemical and - biological properties. This versatility will enable us to create biomimetic human in vitro models of the human bone marrow in health and disease, which are ground-breaking in their applicability to investigate how the regenerative balance of bone - marrow is maintained in health and disturbed in the different kinds of diseases – a prerequisite to develop novel regenerative treatments – as well as their scalability and thus suitability as in vitro test systems for screening of novel drugs or - treatments. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - bloodANDbone - - - ERC-2017-STG - - - 757490 - - - - - SERVICIO MADRILENO DE SALUD - SERVICIO MADRILENO DE SALUD - - - EUR 1 497 314 - - - Understanding the evolution of plasmid-mediated antibiotic resistance in real life scenarios - - - EUR 1 497 314 - - - Spain - Spain - - - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - Antibiotics are essential tools in modern medicine and are indispensable not only for the treatment of infectious diseases but also to support other key interventions such as surgery and cancer chemotherapy. However, the - extensive and inappropriate use of antibiotics has fuelled the spread of resistance mechanisms in pathogenic bacteria, leading to the dawn of a post-antibiotic era. Plasmids play a pivotal role in the evolution of antibiotic resistance (AR) because - they drive the horizontal transfer of resistance genes between pathogenic bacteria by conjugation. Some of these plasmid-bacterium associations become particularly successful, creating superbugs that spread uncontrollably in clinical settings. The - rise of these clones is mainly constricted because plasmids entail a fitness cost when they arrive in a new bacterial host. This cost can be subsequently alleviated through compensatory adaptation during plasmid-bacterium coevolution. Despite the - importance of this cost-compensation dynamic in the evolution of plasmid-mediated AR, it remains completely unexplored in clinical contexts. In this project I plan to bridge this gap by exploring the genetic basis underlying the evolution of - plasmid-mediated AR in clinically relevant scenarios. We will study, for the first time, the intra-patient transmission, fitness cost and adaptation of AR plasmids in the gut microbiome of hospitalized patients (obj. 1). We will analyse the molecular - mechanisms that determine the success of AR plasmids and bacterial clone associations (obj. 2). Finally, we will develop new technology to test how antibiotic treatments affect AR plasmids dynamics in the gut microbiome at an unprecedentedly - high-resolution (obj. 3). This ground-breaking project will allow a new understanding of the evolution of plasmid-mediated AR in real life, opening new research avenues and providing a major step towards meeting one of the central challenges facing - our society: controlling the spread of AR. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Spain - - - PLASREVOLUTION - - - ERC-2017-STG - - - 757440 - - - - - NPL MANAGEMENT LIMITED - NPL MANAGEMENT LIMITED - - - EUR 1 500 000 - - - Interaction and Symmetry Breaking of Counterpropagating Light - - - EUR 1 500 000 - - - United Kingdom - United Kingdom - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Light is generally expected to travel through media independent of its direction. Exceptions can be achieved eg. through polarization changes induced by magnetic fields (known as the Faraday effect) together with - polarization-sensitive birefringent materials. However, light can also be influenced by the presence of a counterpropagating light wave. We have recently shown that this leads to the surprising consequence that light sent into tiny glass rings - (microresonators) can only propagate in one direction, clockwise or counterclockwise, but not in both directions simultaneously. When sending exactly the same state of light (same power and polarization) into a microresonator, nonlinear interaction - induces a spontaneous symmetry breaking in the propagation of light. In this proposal we plan to investigate the fundamental physics and a variety of ground-breaking applications of this effect. In one proposed application, this effect will be used - for optical nonreciprocity and the realization of optical diodes in integrated photonic circuits that do not rely on magnetic fields (an important key element in integrated photonics). In another proposed experiment we plan to use the spontaneous - symmetry breaking to demonstrate microresonator-based optical gyroscopes that have the potential to beat state-of-the-art sensors in both size and sensitivity. Additional research projects include experiments with all-optical logic gates, photonic - memories, and near field sensors based on counterpropagating light states. Finally, we plan to demonstrate a microresonator-based system for the generation of dual-optical frequency combs that can be used for real-time precision spectroscopy in - future lab-on-a-chip applications. On the fundamental physics side, our experiments investigate the interaction of counterpropagating light in a system with periodic boundary conditions. The fundamental nature of this system has the potential to - impact other fields of science far beyond optical physics. - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - CounterLIGHT - - - ERC-2017-STG - - - 756966 - - - - - ERASMUS UNIVERSITEIT ROTTERDAM - ERASMUS UNIVERSITEIT ROTTERDAM - - - EUR 1 261 246 - - - The role of the father in child development and the intergenerational transmission of inequality: Linking sociological stratification questions to developmental psychology research - - - EUR 1 261 246 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The key objective of my FATHERCHILD project is to provide novel insights into the questions whether, why, and in what ways, fathers influence their children’s social, behavioral, emotional, and cognitive outcomes. More - specifically, this project investigates how inequalities in child outcomes develop through fathers’ parenting practices across childhood and adolescence, and how context may buffer or strengthen fathers’ role in this development of inequalities. The - idea underlying the proposed research is that much can be learned about fathers’ role in child outcomes by linking sociological stratification questions to developmental psychology research on father involvement. The relevance of the current project - is apparent: inequality is rising all across Europe, people are increasingly relying on their families to get by, and father involvement has become more polarized according to fathers’ socioeconomic position over the decades. - - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - FATHERCHILD - - - ERC-2017-STG - - - 757210 - - - - - DANMARKS TEKNISKE UNIVERSITET - DANMARKS TEKNISKE UNIVERSITET - - - EUR 1 423 357,50 - - - Deciphering the transport mechanisms of small xenobiotic molecules in synthetic yeast cell factories - - - EUR 1 423 357,50 - - - Denmark - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Industrial biotechnology employs synthetic cell factories to create bulk and fine chemicals and fuels from renewable resources, laying the basis for the future bio-based economy. The major part of the wanted bio-based - chemicals are not native to the host cell, such as yeast, i.e. they are xenobiotic. Some xenobiotic compounds are readily secreted by synthetic cells, some are poorly secreted and some are not secreted at all, but how does this transport occur? Or - why does it not occur? These fundamental questions remain to be answered and this will have great implications on industrial biotechnology, because improved secretion would bring down the production costs and enable the emergence of novel bio-based - products. - - - 2022-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Denmark - - - YEAST-TRANS - - - ERC-2017-STG - - - 757384 - - - - - UNIVERSITY OF GLASGOW - UNIVERSITY OF GLASGOW - - - EUR 1 422 818 - - - Work on Demand: Contracting for Work in a Changing Economy - - - EUR 1 422 818 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Labour law as a scholarly discipline is widely believed to be in crisis. Since the time of its birth, both the nature of working relationships and the context within which they are formed and regulated have changed - significantly. The difficulty for scholars is that old concepts don’t perform the function anymore of making sense of the field. Old arguments about the need to protect workers’ interests are met with counterarguments, informed by neoclassical - economics, that protective measures inhibit economic growth and increase unemployment. - - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - WorkOD - - - ERC-2017-STG - - - 757395 - - - - - THE UNIVERSITY OF WARWICK - THE UNIVERSITY OF WARWICK - - - EUR 1 483 943 - - - Singularities and Compactness in Nonlinear PDEs - - - EUR 1 483 943 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The emergence of singularities, such as oscillations and concentrations, is at the heart of some of the most intriguing problems in the theory of nonlinear PDEs. Rich sources of these phenomena can be found for instance in the - equations of mathematical material science and hyperbolic conservation laws. - - 2023-03-31, Grant Agreement signed - - - 2018-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - SINGULARITY - - - ERC-2017-STG - - - 757254 - - - - - ECOLE NORMALE SUPERIEURE - ECOLE NORMALE SUPERIEURE - - - EUR 1 500 000 - - - Exploring topological matter with atomic Dysprosium - - - EUR 1 500 000 - - - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Recently, topology stepped in an increasing number of areas in physics, including via the concept of topological phases of matter. In strongly interacting systems, topological phases may exhibit intricate quantum entanglement - between their constituents, leading to fascinating physical properties, such as the emergence of anyons. Since the discovery of fractional quantum Hall states in 1982, the scientific community is awaiting further experimental advances: new types of - strongly correlated states, observation/manipulation of anyons. In this field, ultracold atoms promise novel approaches with a specific degree of control. Yet, despite the recent creation of weakly interacting topological states with atomic gases, - reaching the strongly correlated regime, with long-range quantum entanglement, remains an open challenge. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - TOPODY - - - ERC-2017-STG - - - 756722 - - - - - HEINRICH-HEINE-UNIVERSITAET DUESSELDORF - HEINRICH-HEINE-UNIVERSITAET DUESSELDORF - - - EUR 1 494 058,75 - - - The Motor Representation of Sensory Experience - - - EUR 1 494 058,75 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - How do we experience the visual world around us? The traditional view holds that the retinal input is analyzed to reconstruct an internal image that generates our perceptual experience. However, a general theory of how visual - features are experienced in space and time is lacking. The fundamental claim of this grant proposal is that only motor knowledge - i.e. the way we interact with the world - establishes the underlying metric of space and time perception. In this model - view, the spatial and temporal structure of perception is embedded in the processing of neural motor maps. The project moreSense has four major objectives: First, it will unravel how neural motor maps provide the metric for the experience of visual - space. It will be hypothesised that there is no central neural map of space or time but a weighted contribution of all maps. Novel experimental techniques are required to uncover the motor basis of perception, which are available by recent - developments in head-mounted displays and online motion tracking. Second, it will provide a general understanding of time perception being implicitly coded in movement plans to objects in space. Third, results from the first two objectives will be - applied to the long-standing mystery of visual stability and continuity across movements. A bayesian model, supported by quantitative measurements, will demonstrate how information combination from the various motor maps leads naturally to stable and - continuous perception. Fourth, this new theory of space and time perception will be investigated in patients suffering from a breakdown of space perception. The results will establish causal evidence that space and time perception are generated by - processing in motor maps. New rehabilitation procedures will be developed to re-establish spatial perception in these patients. The experiments in this grant proposal will unravel the fundamental spatiotemporal structure of perception which organizes - our sensory experience. - - 2023-03-31, Grant Agreement signed - - - 2018-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - moreSense - - - ERC-2017-STG - - - 757184 - - - - - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - - - EUR 1 499 094 - - - Energetics of natural turbulent flows: the impact of waves and radiation. - - - EUR 1 499 094 - - - France - France - - - Research Organisations - Research Organisations - - Turbulence in natural flows is an outstanding challenge with key implications for the energetics of planets, stars, oceans, and the Earth’s climate system. Such natural flows interact with waves, radiation or a combination - thereof: surface waves and solar radiation on oceans and lakes, bulk waves and radiation inside the rapidly rotating and electrically conducting solar interior, etc. Standard simplified models often discard waves, radiation, or both, with dramatic - consequences for the energy budget of natural flows: geostrophic models neglect waves, and Rayleigh-Bénard thermal convection considers heat diffusively injected through a solid boundary, in strong contrast with radiative heating. The purpose of the - present multidisciplinary project is to develop a consistent and coupled description of natural flows interacting with waves and radiation, to properly assess their energy budget: - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - FLAVE - - - ERC-2017-STG - - - 757239 - - - - - TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY - TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY - - - EUR 1 486 480 - - - The cost of limited communication bandwidth in distributed computing - - - EUR 1 486 480 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Distributed systems underlie many modern technologies, a prime example being the Internet. The ever-increasing abundance of distributed systems necessitates their design and usage to be backed by strong theoretical foundations. - - 2023-05-31, Grant Agreement signed - - - 2018-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Israel - - - BANDWIDTH - - - ERC-2017-STG - - - 755839 - - - - - THE HEBREW UNIVERSITY OF JERUSALEM - THE HEBREW UNIVERSITY OF JERUSALEM - - - EUR 1 499 875 - - - Mechanical Targeting as an Integrative Approach for Personalized Nanomedicine - - - EUR 1 499 875 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The ability to direct drug delivery to specific tissues is a central challenge in treating diseases as it determines the balance between drug selectivity and toxicity. Clinical drug failures, commonly due to safety issues or - poor efficacy, are extremely costly to the pharmaceutical industry. In light of this, there is a global effort to develop Targeted Drug Delivery Systems (DDS) and Nanomedicine-based drugs to increase the therapeutic efficacy of a drug while - substantially reducing its off-target exposure. In oncology, this issue is critical since chemotherapies have poor selectivity, thus causing severe side effects due to undesired systemic exposure. However, the enormous heterogeneity and dynamic - nature of tumors makes it extremely challenging to identify universal target molecules. In this ERC I introduce a novel concept according to which the specificity of DDS can be dramatically enhanced by tuning the physical parameters of DDS based on - mechanical cues of target and non-target cells. In many cancers, it is well-established that the flexibility and deformability of cells are correlated with their metastatic potential. This leads to our hypothesis that the enhanced deformability of - cancer cells allows them to engulf and uptake particles whose internalization requires massive shape change, unlike the stiffer and normal cells. The rationale of the proposed study is that by considering physical parameters of cells, the mechanical - properties of DDS can be tuned to achieve selective uptake. We thus propose to develop tools for rational design of DDS for personalized nanomedicine that will use simple tests performed on a patient’s own cells. This is the basis of our visionary - Mechanical Targeting (MT) scheme, a crosstalk between experimental and computational models, for drug specificity. Accordingly, this ERC is expected to yield breakthroughs, both conceptual and technical. - - 2022-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Israel - - - MTrix - - - ERC-2017-STG - - - 756762 - - - - - BANGOR UNIVERSITY - BANGOR UNIVERSITY - QUEEN MARY UNIVERSITY OF LONDON - - - EUR 1 458 770 - - - National parks and people: Resolving the links between poverty and rule-breaking - - - EUR 1 458 770 - - - United Kingdom - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Poverty is frequently perceived to be the root cause of illegal natural resource use – the hunting or extraction of wildlife not sanctioned by the state. When unsustainable, such activities threaten conservation of ecosystems - and endangered species. However, understanding what motivates individuals involved is a major challenge; understandably few are willing to discuss their motives for fear of punishment [1]. Furthermore, severe, multifaceted poverty overlaps with - regions prioritised for their globally important biodiversity [2]. This association exacerbates the problem that illegal activities pose for policy-makers responsible for managing and policing the use of nature. The dominant approach to conserving - biodiversity is to establish protected areas [3] which typically restrict resource use and manage infractions through law enforcement [4]. However, the designation of such areas does not guarantee compliance, as demonstrated by ongoing infractions - [5] and its conspicuous profile on global policy agendas. This includes the 2030 Agenda for Sustainable Development which calls for urgent action to halt biodiversity loss and hunting of protected species [6]. Solving this problematic cocktail of - poverty, exclusion from resources and drivers of illegal resource use requires a new approach to understanding why people break rules and to what extent poverty underpins behaviour. Recent advances in cutting-edge techniques for asking sensitive - questions are paving the way towards a more accurate understanding of the prevalence and drivers of illegal acts [7]. Combining conservation social science with development studies, criminology and social psychology, this project will examine, for - the 1st time, the relative importance of multidimensional poverty and socio-psychological characteristics in dictating people’s involvement in illegal resource use which will be contextualised by histories of national park establishment and how the - idea of illegality shifts through time. - - 2023-05-31, Grant Agreement signed - - - 2018-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - WILDPOV - - - ERC-2017-STG - - - 755965 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 1 445 000 - - - Cooperative Catalysis: Using Interdisciplinary Chemical Systems to Develop New Cooperative Catalysts - - - EUR 1 445 000 - - - Spain - Spain - - - Research Organisations - Research Organisations - - Catalysis, a multidisciplinary science at the heart of many industrial processes, is crucial to deliver future growth and minimize anthropogenic environmental impact, thus being critical to our quality of life. Thus, the - development and fundamental understanding of innovative new catalyst systems has clear, direct and long-term benefits to the chemical manufacturing sector and to the broader knowledge-based economy. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Spain - - - CoopCat - - - ERC-2017-STG - - - 756575 - - - - - THE HEBREW UNIVERSITY OF JERUSALEM - THE HEBREW UNIVERSITY OF JERUSALEM - - - EUR 1 570 000 - - - Translating rewards to eye movements - - - EUR 1 570 000 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The drive for rewards controls almost every aspect of our behavior, from stereotypic reflexive behaviors to complex voluntary action. It is therefore not surprising that the symptoms of neurological disorders that interrupt - reward processing, such as those stemming from drug-abuse and depression, include deficits in the capacity to make even simple movements. Accordingly, how do rewards drive and shape movements? The brain uses two major subcortical networks to drive - behavior: the basal ganglia and the cerebellum. Both areas are essential for the control of movement as damage to either structure leads to severe motor disabilities. Research on the basal ganglia has highlighted their importance in the control of - reward-driven behavior-but how the reward information interacts with sensorimotor signals to drive the motor periphery is unknown. By contrast, research on the cerebellum has focused primarily on how sensory error signals are used to optimize motor - commands but has mostly ignored the modulatory factors that influence behavior, such as reward. My goal is to unify research on the basal ganglia and cerebellum in order to understand how the computations underlying the influence of reward on action - are implemented in the brain. I hypothesize that rewards drive and shape the motor commands in both subcortical networks, albeit with differing behavioral functions. While in the basal ganglia, information about reward is used to mediate selection - between multiple actions; I predict that, in the cerebellum, reward potentiates movements to drive more accurate behavior. I will use the monkey smooth pursuit eye movement system as a powerful model motor system to study the neural mechanisms by - which reward influences motor processing. I will combine the use of novel behavioral paradigms together with novel application of neural recording and optogenetic stimulation in primates to probe activity of neurons in the cerebral cortex, basal - ganglia, and cerebellum. - - 2023-06-30, Grant Agreement signed - - - 2018-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Israel - - - iMove - - - ERC-2017-STG - - - 755745 - - - - - UNIVERSITY OF CYPRUS - UNIVERSITY OF CYPRUS - THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - - - EUR 1 499 444 - - - Decomposing Heterogeneity in Autism Spectrum Disorders - - - EUR 1 499 444 - - - Cyprus - Cyprus - United States - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Autism spectrum disorders (ASD) affect 1-2% of the population and are a major public health issue. Heterogeneity between affected ASD individuals is substantial both at clinical and etiological levels, thus warranting the idea - that we should begin characterizing the ASD population as multiple kinds of ‘autisms’. Without an advanced understanding of how heterogeneity manifests in ASD, it is likely that we will not make pronounced progress towards translational research - goals that can have real impact on patient’s lives. This research program is focused on decomposing heterogeneity in ASD at multiple levels of analysis. Using multiple ‘big data’ resources that are both ‘broad’ (large sample size) and ‘deep’ - (multiple levels of analysis measured within each individual), I will examine how known variables such as sex, early language development, early social preferences, and early intervention treatment response may be important stratification variables - that differentiate ASD subgroups at phenotypic, neural systems/circuits, and genomic levels of analysis. In addition to examining known stratification variables, this research program will engage in data-driven discovery via application of advanced - unsupervised computational techniques that can highlight novel multivariate distinctions in the data that signal important ASD subgroups. These data-driven approaches may hold promise for discovering novel ASD subgroups at biological and phenotypic - levels of analysis that may be valuable for prioritization in future work developing personalized assessment, monitoring, and treatment strategies for subsets of the ASD population. By enhancing the precision of our understanding about multiple - subtypes of ASD this work will help accelerate progress towards the ideals of personalized medicine and help to reduce the burden of ASD on individuals, families, and society. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Cyprus - - - AUTISMS - - - ERC-2017-STG - - - 755816 - - - - - TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY - TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY - - - EUR 1 500 000 - - - Memristive In-Memory Processing System - - - EUR 1 500 000 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Our project aims to develop a new computer architecture that enables true in-memory processing based on a unit that can both store and process data using the same cells. This unit, called a memristive memory processing unit - (mMPU), will substantially reduce the necessity to move data in computing systems, solving the two main bottlenecks exist in current computing systems, i.e., speed ('memory wall') and energy efficiency ('power wall'). Emerging memory technologies, - namely memristive devices, are the enablers of the mMPU. While memristors are naturally used as memory, these novel devices can also perform logical operations using a technique we have invented called Memristor Aided Logic (MAGIC). This combination - is the basis of mMPU. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Israel - - - Real-PIM-System - - - ERC-2017-STG - - - 757259 - - - - - UNIVERSITY OF YORK - UNIVERSITY OF YORK - - - EUR 1 223 054 - - - From mind to mind: Investigating the cultural transmission of intergroup bias in children - - - EUR 1 223 054 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Prejudice and discrimination are pressing social problems. Across Europe, the far right is on the rise, and individuals are often discriminated against on the basis of their race, gender or sexual orientation. The origins of - these problematic attitudes and behaviours appear early in development, suggesting that we are passing on our biases to our children. Yet, our knowledge of the complex psychological processes by which these biases are learned remains rudimentary. - MINDTOMIND experimentally investigates how children encode, select and transmit biased social information, and so provides a framework for understanding how intergroup attitudes are perpetuated across generations. - - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - MINDTOMIND - - - ERC-2017-STG - - - 755719 - - - - - TEL AVIV UNIVERSITY - TEL AVIV UNIVERSITY - - - EUR 1 492 249,99 - - - Human Trafficking: A Labor Perspective - - - EUR 1 492 249,99 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project conducts a theoretical, methodological, and normative paradigm shift in the research and analysis of human trafficking, one of the most pressing moral and political challenges of our times. It moves away from the - currently predominant approach to trafficking, which focuses on criminal law, border control, and human rights, towards a labor-based approach that targets the structure of labor markets that are prone to severely exploitative labor practices. This - shift represents an essential development both in the research of migratory labor practices and in the process of designing more effective, and more just, anti-trafficking measures, that are context-sensitive as well as cognizant to global legal and - economic trends. The project will include four main parts: 1) Theoretical: articulating and justifying the proposed shift on trafficking from individual rights and culpabilities to structural labor market realities. 2) Case-studies: conducting a - multidisciplinary study of a series of innovative case studies, in which the labor context emerges as a significant factor in the trafficking nexus – bilateral agreements on migration, national regulations of labor standards and recruiters, - unionization, and voluntary corporate codes of conduct. The case studies analysis employs the labor paradigm in elucidating the structural conditions that underlie trafficking, reveal a thus-far mostly unrecognized and under-theorized set of - anti-trafficking tools. 3) Clinical Laboratory: collaborating with TAUs Workers' Rights clinic to create a legal laboratory in which the potential and limits of the tools examined in the case studies will be tested. 4) Normative: assessing the - success of existing strategies and expanding on them to devise innovative tools for a just, practicable, and effective anti-trafficking policy, that can reach significantly more individuals vulnerable to trafficking, by providing them with legal - mechanisms for avoiding and resisting exploitation. - - 2023-03-31, Grant Agreement signed - - - 2018-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Israel - - - HumanTrafficking - - - ERC-2017-STG - - - 756672 - - - - - NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA - NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA - "NATIONAL CENTER FOR SCIENTIFIC RESEARCH ""DEMOKRITOS""" - - - EUR 149 730 - - - Commercialization of a novel method for fabricating cheap tailor–made superhydrophobic surfaces - - - EUR 149 730 - - - Greece - Greece - Greece - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - The aim of the HYDROPHO-CHEAP project is to optimize, protect, and commercialize a recently developed methodology that allowed us to achieve “tailor-made” control of the wettability of polymer surfaces, rendering them super water-repellent. - - - 2019-07-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Greece - - - HYDROPHO-CHEAP - - - ERC-2016-PoC - - - 755412 - - - - - THE UNIVERSITY OF BIRMINGHAM - THE UNIVERSITY OF BIRMINGHAM - - - EUR 149 688 - - - Direct detection of cancer-causing mutations in tumour specimens - - - EUR 149 688 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Cancers develop because they acquire changes (mutations) in a specific set of genes that promote their growth. Different mutations are associated with cancer aggressiveness, patient prognosis and/or the response to treatment. - Although these mutations can usually be detected by extracting DNA from tumour specimens, this provides incomplete information because it is common for mutations not to occur in every cell that makes up the cancer. In a number of research and - clinical settings, it is of great use to learn which regions or cells within a cancer carry a particular mutation. To do this, we need to detect mutations in space by examining sections of tissue. There are several potential benefits, including - sensitive detection of cancer cells that have been left behind after operation or that will cause relapse after treatment. Here, we shall develop a method to detect mutations in situ in cancer specimens. The INSITUMUT technique uses molecular probes - that are specific to mutations in cancer genes and bind to RNA expressed from those genes. We have piloted the method successfully in collaboration with Advanced Cellular Diagnostics Inc., sensitively identifying cancer cells that have acquired - specific mutations in the oncogene KRAS and specifically distinguishing them from cells and cancers with normal KRAS. Before making the method available, our workplan in this proposal involves determining probe sensitivity and specificity more - accurately, expanding the range of cancer-causing mutations that are detected, developing methods for simultaneous detection of multiple mutations, extending the technique as far as possible to detection of mutations in DNA, and automating the - mutation detection process. Subject to technical feasibility and commercial assessments, we shall disseminate the INSITUMUT method to non-profit sectors on a cost recovery basis, and make it generally available as a commercial service in partnership - with SME partner Oxford Cancer Biomarkers. - - 2019-08-31, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - INSITUMUT - - - ERC-2016-PoC - - - 755211 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 499 632 - - - De novo structural elucidation of functional organic powders at natural isotopic abundance - - - EUR 1 499 632 - - - France - France - - - Research Organisations - Research Organisations - - Structure holds the key to many of the physical world’s most intriguing secrets. Diffraction from single crystals has revolutionized our knowledge of crystalline matter by providing atomic-scale images of countless samples and - leading to landmark achievements in science. However, when crystals of sufficient dimensions cannot be grown, structure can hardly be retrieved using currently available methodologies. This hampers our understanding of the physico-chemical behavior - of numerous samples, such as functional organic powders (FOP), hence precluding the design of new materials with tailored properties. Solid-state NMR (SSNMR) has the potential to be the key to access the structure of powders for applications in - energy or pharmacy. However, the inherently low sensitivity of NMR constitutes the main barrier to retrieve valuable constraints such as interatomic distances and torsional angles from spin-spin couplings involving rare nuclei (e.g. C-13, N-15) on - organic samples at natural isotopic abundance (NA), for which chemical shifts are certainly easier to access but less structurally relevant. The project will capitalize on Dynamic Nuclear Polarization (DNP) to enhance the sensitivity of SSNMR and - obtain unique structural constraints on NA FOPs. Specifically: (i) intra and intermolecular distances, torsional/bond angles and H bonds will be measured for the first time via DNP SSNMR; (ii) together with powder X-ray data, these constraints will - be integrated within modern computational algorithms to assist the generation of physically meaningful 3D structures with minimized risk of false positives. The protocol will be applied to time-resolved in situ/ex situ investigation of self-assembly - to gain control into polymorph production. We will create an integrated experimental/in silico tool that will extend the proficiency of crystallography in de novo structure elucidation of FOPs of increasing complexity, opening new avenues in - chemistry and materials science. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - STRUCTURE - - - ERC-2017-STG - - - 758498 - - - - - PARMENIDES STIFTUNG - PARMENIDES STIFTUNG - ECOLE SUPERIEURE DE PHYSIQUE ET DECHIMIE INDUSTRIELLES DE LA VILLE DEPARIS - - - EUR 150 000 - - - OncoSeq: an innovative single-cell system for immunomonitoring - - - EUR 150 000 - - - Germany - Germany - France - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - - Host immunity plays a central and complex role in tumour progression, and the quality and quantity of immune infiltrate at the tumour site is used as a prognostic marker of cancer progression. Therefore, detailed single-cell - analysis of tumor infiltrating immune cells, and ultimately liquid biopsy of circulating immune cells, is of vital importance for the development of new and improved immunotherapy strategies, and for diagnosis, prognosis, patient stratification and - follow-up. - - 2018-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Germany - - - OncoSeq - - - ERC-2017-PoC - - - 780964 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 1 499 955 - - - The search for new physics through precision measurements of the CKM angle gamma - - - EUR 1 499 955 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - There is a strong conviction that the Standard Model of particle physics is only a low energy approximation to a higher energy theory containing new fundamental particles. For example, it is not possible to explain the large - asymmetry between the properties of matter and anti-matter that must exist to create the universe within we live, with the Standard Model that can only accommodate asymmetries orders of magnitude smaller. The theoretical framework that describes - these asymmetries is the Cabibbo-Maskawa-Kobayashi (CKM) matrix. - - - 2023-05-31, Grant Agreement signed - - - 2018-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - ONEDEGGAM - - - ERC-2017-STG - - - 758462 - - - - - NATIONAL UNIVERSITY OF IRELAND GALWAY - - - EUR 175 866 - - - SUGARSmart: Smart design of recombinant antibody fragments specific for carbohydrate molecules - - - EUR 175 866 - - - Ireland - - - Higher or Secondary Education Establishments - - The development of new approaches to explore the diverse role of glycans in normal and physio- pathological conditions of the cell is a major challenge. Our previous research recognized roles of anti-glycan recognition - molecules (lectins and antibodies) in the diagnosis of diseases like cancer, immunity, and hyperacute rejection upon bioprosthetic transplantation etc. However, because of the structural complexity, well-established approaches for developing - glycan-based therapeutics are limited. - - 2020-05-14, Grant Agreement signed - - - 2018-05-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Ireland - - - SUGARSmart - - - H2020-MSCA-IF-2016 - - - 747948 - - - - - ECOLE NORMALE SUPERIEURE - ECOLE NORMALE SUPERIEURE - - - EUR 1 499 125 - - - Geodetic data assimilation: Forecasting Deformation with InSAR - - - EUR 1 499 125 - - - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Recent space-based geodetic measurements of ground deformation suggest a paradigm shift is required in our understanding of the behaviour of active tectonic faults. The classic view of faults classified in two groups – the - locked faults prone to generate earthquakes and the creeping faults releasing stress through continuous aseismic slip – is now obscured by more and more studies shedding light on a wide variety of seismic and aseismic slip events of variable duration - and size. What physical mechanism controls whether a tectonic fault will generate a dynamic, catastrophic rupture or gently release energy aseismically? Answering such a fundamental question requires a tool for systematic and global detection of all - modes of slip along active faults. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - GEO-4D - - - ERC-2017-STG - - - 758210 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - MASSACHUSETTS INSTITUTE OF TECHNOLOGY - - - EUR 269 857,80 - - - Cavity-mediated entanglement of trapped-ion qubit arrays for quantum information processing - - - EUR 269 857,80 - - - United Kingdom - United States - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Long-coherence times, high-fidelity individual-ion control and entanglement-mediating Coulomb interactions make trapped-ion qubits a very attractive platform for quantum information processing (QIP). Entangling gates performed - by coupling the internal states of ions in the same potential well via their shared motional mode have recently reached the high fidelities necessary for the implementation of quantum error correction protocols which can enable fault-tolerant QIP. - However, scaling this type of gate up to long ion chains (>20 ions) is not feasible: large ion numbers lead to crowding of the motional mode spectrum of the chain, eventually preventing addressing of specific modes. - - 2021-10-31, Grant Agreement signed - - - 2018-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - CMEQIP - - - H2020-MSCA-IF-2016 - - - 753788 - - - - - SYDDANSK UNIVERSITET - INSTITUTO SUPERIOR DE ENGENHARIA DE LISBOA - PANEPISTIMIO PATRON - CONSIGLIO NAZIONALE DELLE RICERCHE - CHIMIKOTECHNOLOGITCHEN I METALURGITCHEN UNIVERSITET - UNIVERSIDAD DE SALAMANCA - UNIVERSITY COLLEGE LONDON - INSTITUT PO INZHENERNA HIMIYA - SANTZOUK SAMIR & CO GENERAL PARTNERSHIP - UNIVERSIDADE FEDERAL DO PARANA - TEXAS ENGINEERING EXPERIMENT STATION - TEES - TECNOLOGICO NACIONAL DE MEXICO - - - EUR 594 000 - - - Integrated Process and Product Design for Sustainable Biorefineries - - - EUR 684 000 - - - Denmark - Portugal - Greece - Italy - Bulgaria - Spain - United Kingdom - Bulgaria - Greece - Brazil - United States - Mexico - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Bio-based economy in Europe involves 22 million people and turns over roughly 2.4 billion €. The full realization of its huge potential, however, requires expert knowledge and synergy of different competencies. In particular, - key questions and bottlenecks awaiting clear answers are: - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Denmark - - - IProPBio - - - H2020-MSCA-RISE-2017 - - - 778168 - - - - - CENTRE DE RECERCA EN AGRIGENOMICA CSIC-IRTA-UAB-UB - - - EUR 170 121,60 - - - Exploring the role of the mitochondrial alternative respiration in carotenoid biosynthesis during tomato fruit ripening - - - EUR 170 121,60 - - - Spain - - - Research Organisations - - Tomato is one of the most economically relevant crops in the world and is the main model system for fruit ripening studies at biochemical, genetic and molecular levels. In this climacteric fruit, a sudden increase in - respiration takes place at the onset of ripening, usually in concert with increased production of ethylene that eventually impacts fruit color, firmness, taste, and flavor. During ripening, tomato accumulates high contents of health-promoting - carotenoids (pro-vitamin A, antioxidants), which require a high production of carbon precursors and ATP. In this respect, both mitochondrial and chromoplast respiration have been proposed to play important roles in fruit ripening and carotenoid - metabolism. The general aim of this project is to determine the contribution of mitochondrial respiration to the supply of energy and carbon for the production of carotenoids in tomato fruit during ripening. In particular, we will perform - metabolomics of genetically modified tomatoes with altered mitochondrial and chromoplast respiration at different ripening stages. Furthermore, 13C- and 14C-labelling experiments will be performed to trace the fate of carbon from primary to secondary - metabolites. In parallel, we will measure the relative glycolytic and TCA cycle fluxes and, for the first time in tomato, the in vivo activities of mitochondrial electron transport chain pathways by using the 18O fractionation technique. Combining - these data with the analysis of transcript and protein levels of the main components of respiratory and carotenoid pathways and mathematical modelling will unveil novel metabolic checkpoints and connections between primary and secondary metabolism - during fruit ripening. The generated new insights should contribute to the implementation of new biotechnological approaches to produce fruits with enhanced levels of carotenoids and other health-promoting secondary metabolites. - - 2020-09-30, Grant Agreement signed - - - 2018-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - ARCATOM - - - H2020-MSCA-IF-2016 - - - 753301 - - - - - ATHENS UNIVERSITY OF ECONOMICS AND BUSINESS - RESEARCH CENTER - - - EUR 152 653,20 - - - Video streaming services with Software-Defined Networking - - - EUR 152 653,20 - - - Greece - - - Higher or Secondary Education Establishments - - Recent advances in mobile devices and video streaming services have motivated large-scale media consumption both in fixed and mobile environments. In this context, the main objective of network operators and service providers - is to improve the Quality of Experience (QoE) of the end-users by providing high quality services and mechanisms for seamless - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - Greece - - - VSDN - - - H2020-MSCA-IF-2016 - - - 753685 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 123 138 - - - Large Deviations and Rare Transitions in Turbulent flows - - - EUR 123 138 - - - France - - - Research Organisations - - Many out-of-equilibrium systems undergo transitions from one quasi-stationary state to a radically different one. - - 2019-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - TransTurb - - - H2020-MSCA-IF-2016 - - - 753021 - - - - - TRANSMODE SYSTEMS AB - - - EUR 185 857,20 - - - NExt-generation WDM Metro and Access Networks - - - EUR 185 857,20 - - - Sweden - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The primary goal of the NEWMAN project is to train a talented researcher with a strong academic background in fibre-optic communication, through a research programme focused on developing next generation - wavelength-division-multiplexing (WDM) technologies, and their usage as a for metro and access optical communication networks. The aimed WDM technologies supporting low-cost low energy consumption are highly desirable, since the number of metro and - access links are forecasted to be massive in the next generation networks and will contribute to major portion of total energy consumption of the global network. The success of this project will contribute knowledge to the fields of laser science and - fibre-optic technology, and establish an internationally leading position for Europe in the industrial applications relevant to fibre-optic networks. - - 2020-02-29, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-SE - Society and Enterprise panel - - - Sweden - - - NEWMAN - - - H2020-MSCA-IF-2016 - - - 752826 - - - - - KERRY INGREDIENTS (IRELAND) LIMITED - - - EUR 187 866 - - - Vegetable proteins: a novel source of next generation functional hydrolysates - - - EUR 187 866 - - - Ireland - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Research is now focused on the potential contribution of plant-based proteins to help solve key issues pertaining to global food security. Protein hydrolysates have numerous properties which make them an attractive protein - source in human nutrition and are utilized in many commercial food applications. Hydrolysed vegetable proteins (HVP) have demonstrated bioactive and techno-functional properties that can be further exploited for the development of functional-foods. - The HVP market is dominated by soy varieties, and there is now a growing demand for alternative plant based sources. However, significant research advances are required in order to increase the direct use of plant protein for human food consumption, - with a particular emphasis on extraction and processing technologies used to derive increased nutritional value and improved functional physical properties. From a commercial standpoint, vegetable proteins have taste attributes such as chalkiness and - bitterness which present a major challenge in commercialization. This project will address the significant potential for application of superior tasting vegetable protein hydrolysates with improved food use properties for the functional foods market - globally; this will be achieved by investigating the efficacy of a range of commercially available proteases in producing HVPs under controlled enzymatic conditions using a variety of vegetable substrates. Degree of hydrolysis, protein recovery, - chemical composition and techno-functional properties of HVPs will be compared/contrasted before further optimization of characters, e.g. de-bittering, solubility, necessary for the their implementation in end use markets. Our primary goal is to - engineer a clean tasting HVP with improved sensory and techno-functional capacity and an enzyme system suitable for its production. - - 2019-11-05, ongoing project - - - 2017-11-06 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-SE - Society and Enterprise panel - - - Ireland - - - VegProtein - - - H2020-MSCA-IF-2016 - - - 752923 - - - - - FUNDACAO CALOUSTE GULBENKIAN - - - EUR 160 635,60 - - - Control of disease tolerance to infection by Biliverdin Reductase A - - - EUR 160 635,60 - - - Portugal - - - Research Organisations - - The immune system was shaped through evolution, primarily through the selective pressure imposed by pathogens. This led to the emergence of multiple mechanisms that limit the negative impact of pathogens on host health and - fitness. The best recognized defense strategy against infections relies on resistance mechanisms that aim at pathogen containment, expulsion or clearance. While crucial for host survival to infection, resistance mechanisms can carry significant - trade-offs, often driven by oxidative stress and damage imposed to host parenchyma cells, and in some cases compromising the functional output of host tissues, i.e. immunopathology. Presumably for this reason, resistance mechanisms are coupled to - countervailing oxidative stress responses that preserve parenchyma tissue function. These provide tissue damage control without exerting a direct negative impact on pathogens and as such are said to confer disease tolerance to infection. This defense - strategy relies on the expression of a number of evolutionary conserved effector genes controlling the pro-oxidant effects of iron and heme, as illustrated for the heme catabolizing enzyme heme oxygenase 1 or the iron sequestering protein ferritin H - chain. BILITOLERANCE aims at identifying and characterizing an unexplored and possibly central component of this tissue damage control mechanism that relies on the conversion of the end-product of heme catabolism biliverdin into bilirubin, by - biliverdin reductase A (BVRA). The central hypothesis to be tested by BILITOLERANCE is that bilirubin generated by BVRA provides a potent lipophilic anti-oxidant defense mechanism that limits the deleterious effects of lipid peroxidation. Moreover - BILITOLERANCE will test the hypothesis that bilirubin also signals via the aryl hydrocarbon receptor (AhR) to modulate the activation of tissue-resident macrophages and promote tissue damage control and disease tolerance to infection. - - 2020-11-30, Grant Agreement signed - - - 2018-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Portugal - - - BILITOLERANCE - - - H2020-MSCA-IF-2016 - - - 753236 - - - - - SCIENCE AND TECHNOLOGY FACILITIES COUNCIL - - - EUR 183 454,80 - - - Direct and indirect searches for new physics in events with top quarks using LHC proton-proton collisions at the CMS detector - - - EUR 183 454,80 - - - United Kingdom - - - Research Organisations - - We look for new physics in events with top quarks using LHC proton-proton collisions at the CMS detector. A direct search for top quark partners in the form of vector-like quarks is performed, complemented by an indirect but - model-independent search for new physics interacting with top quarks using precision top quark properties measurements. In order to enable these and similar analyses to continue at the future High Luminosity LHC, we study the performance of the - upgraded track trigger for events with top quarks, including optimisation of reconstruction algorithms and working points. - - 2019-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - LHCTOPVLQ - - - H2020-MSCA-IF-2016 - - - 752730 - - - - - FONDATION NATIONALE DES SCIENCES POLITIQUES - - - EUR 185 076 - - - Male Family Caregiver’s Well-being: Balancing Work and Long-Term Care in France and Japan - - - EUR 185 076 - - - France - - - Higher or Secondary Education Establishments - - Rapid demographic ageing in Europe, as highlighted in Horizon 2020 health priorities, makes the challenge of long-term care increasingly pressing. Despite substantial discussions on caregivers in policy making and academic - research, a rapidly emerging new group of relatively young male family primary caregivers who often also work are largely understudied and increasingly risk giving up their employment. Inadequate understanding of gendered caregivers jeopardises not - only carers but also care receivers, other family members and society as a whole: better outcomes for the elderly are substantially dependent on the well-being of caregivers. For Europe it is relevant and timely to learn from ‘super-aged’ Japan about - such gendered carers’ practices, particularly their use of innovative ‘technologised care’ emphasised by Japan’s large-scale welfare programme. Yet, learnings need to be contextualised to reflect European societies, such as France’s highly developed - family policies. Hence, this project aims to address the gap in understanding of gendered male family care practices to inform policy development, focusing on the relevance and application in France of practices from Japan. This project will develop - an innovative multidisciplinary approach to comparative understanding and policy development: building on the researcher’s anthropological PhD on men and masculinities in family the project develops ‘short-duration fieldwork’ in Paris and Tokyo, - which is complemented by capabilities developed through training by hosts Science Po and Oxford in sociology and policy analysis. The project findings will be disseminated to potential users, such as policy makers, academic and non-academic - researchers, also by organising an international workshop and to the public through popular media. The research project develops the researcher’s specific capabilities and transferable professional skills that substantially open up new career paths, - notably in policy research in Europe. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - CAREANDWORK - - - H2020-MSCA-IF-2016 - - - 753717 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - - - EUR 187 866 - - - Computer-aided Van der Waal Heterostructure Device Design using Unique Response to Electric Fields - - - EUR 187 866 - - - Ireland - - - Higher or Secondary Education Establishments - - The van der Waals heterostructure has been a central focus of materials research and nanotechnology for a decade. It is because this heterostructure can provide device platform highly flexible for materials combination. Thanks - to those advantages, this heterostructure system is highlighted for potential application for flexible and low-power consumption electronics. In this research proposal, we will propose new device architecture using novel 2D physics under an electric - field. Because of its low-dimensional nature and transparency of electric field, the band structure at the heterostructure can be remarkably modulated. Our objective is to design new device architecture using this phenomenon. To achieve it, we will - find out best heterostructure using high-throughput calculations and will design the device architecture. Then, we will simulate the device characteristics using DFT-NEGF method and validate it experimentally. This approach is pioneering for coming - up with new device architecture, which will open a new direction beyond the state-of-the-art. Thanks to its novelty, it is expected to have a high impact in the fields of physics, materials science, and nanoelectronics. Through this research project, - the applicant will obtain valuable opportunity for career development and will promote interdisciplinary nature of this research field. - - 2020-11-19, Grant Agreement signed - - - 2018-11-20 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Ireland - - - VHDD - - - H2020-MSCA-IF-2016 - - - 751581 - - - - - INSTYTUT CHEMII FIZYCZNEJ POLSKIEJ AKADEMII NAUK - - - EUR 134 462,40 - - - Ultrafast photonics for the detection and recognition of toxic spine-structures of amyloid aggregates linked to neurodegenerative disease - - - EUR 134 462,40 - - - Poland - - - Higher or Secondary Education Establishments - - Projections indicate that, by 2050, every person aged 85 years or more will be diagnosed with a cognition-related disease. While there is currently no clear strategy for curing such diseases, there are promising developments - in the early diagnosis of disease and the inhibition of worsening symptoms. Building on results obtained during my post-doctoral work regarding laser technology for amyloid aggregates detection, I propose to use an advanced ultrafast spectroscopy for - structural analyses of the peptides and proteins that form the different fibril architectures in the brains of patients with pathogenic aggregates. In combination with multiphoton absorption, this laser technique has the potential to detect and - diagnose in a non-invasive modality the early forms of toxic oligomeric intermediates in the brains of persons with suspected Alzheimer´s or Parkinson´s disease. This methodology has potentially enormous benefits for patients and society. - Importantly, the proposed approach of using high-intensity light in the infrared region of absorption does not damage cells and tissues during long-duration irradiation, it does not require the use of chemical labels, and it reduces the need for - surgical intervention, as it is non-invasive and safe for human health. I will transfer the knowledge and expertise on biophotonics of amyloid fibrils to Europe and the Host laboratory at the Polish Academy of Science will provide me with advanced - training in time-resolved ultrafast laser spectroscopy and access to newly designed setups, as well as supplementary career path-specific training in ancillary skills. - - 2020-02-29, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Poland - - - UPRECON - - - H2020-MSCA-IF-2016 - - - 750917 - - - - - THE UNIVERSITY OF SHEFFIELD - - - EUR 195 454,80 - - - optimal design of Admixtures for concrete embedded Large Scale Antenna Array - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Large scale antenna array (LSAA) has been introduced into 5G cellular networks to address the capacity crunch indoors. LSAAs will increase the physical dimension of the base station (BS), generating negative consequences on - weight, wind load and visual impact. A potential solution of deploying LSAA indoors is to embed it into building structures, e.g., concrete walls. However, how the concrete impacts the wireless performance of concrete embedded antenna array (CEAA) - has not been well studied. In this project, we will investigate how the electromagnetic (EM) properties of concrete will impact the wireless performance of CEAAs, and how to design and optimise the building properties of concrete to achieve both - desirable mechanical and wireless performance. First, we will define metrics so that the wireless performance of CEAA can be measured. EM properties of concrete and the inhomogeneity of EM properties will be taken into account. Then, we will - establish the relationship between the ratio and layout of admixtures and the EM properties of concrete. Three simplified concrete model, i.e., multilayer, lattice and 3D Poisson point process (PPP) models, will be proposed and verified through - simulations and measurements. Finally, we will design concrete with desirable EM properties by changing the ratio and layout of admixtures under the constraint of mechanical performance to obtain an optimal wireless performance. After the completion - of this project, we will be able tell how to optimize wireless performance of concrete under the constraint of its mechanical performance for typical building structures. - - 2020-11-30, Grant Agreement signed - - - 2018-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - AceLSAA - - - H2020-MSCA-IF-2016 - - - 752644 - - - - - UNIVERSITEIT LEIDEN - - - EUR 165 598,80 - - - Cyclometallated ruthenium complexes for photo-activated chemotherapy - - - EUR 165 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Chemotherapy is efficient in curing cancer, but most treatments are very hard to stand for the patient, and side effects limit treatment efficacy. Phototherapy is a promising alternative, where the toxicity of a - light-sensitive chemotherapeutic compound is locally released upon visible light irradiation of the compound-containing tumour. Photodynamic therapy is already available in the clinic for oxygen-rich tumours; however, it fails when the oxygen - concentration at the place of irradiation is too low. In this project I propose to synthesize new ruthenium-based photochemotherapeutic compounds containing cyclometallated ligand, and to test them in an in vitro model of hypoxic cancer. The presence - of a carbon-metal bond is known to shift the light absorption properties of ruthenium polypyridyl complexes towards the photodynamic window, a wavelength range where light penetrates optimally into biological tissues. However, cyclometallation - usually quenches the ligand photosubstitution properties of ruthenium compounds because it strongly modifies the energy of their excited states. In this project, I will introduce sterically hindering groups on the cyclometallated ligand to recover - photoreactivity of the complexes while keeping light absorption at high wavelengths. The challenges of this project consist on the one hand in achieving efficient ligand photosubstitution reactions with cyclometallated ruthenium compounds, and on the - other hand in minimizing the cytotoxicity in the dark while maximizing cytotoxicity after red light irradiation at low oxygen concentrations. The ruthenium prodrugs will be synthesized, their photochemical properties will be measured, and their - cytotoxicity against human cancer cell lines will be determined in an in vitro model of hypoxic cancer. This project will set new grounds in the treatment of hypoxic tumours and propose a new way to overcome side effects occurring in traditional - anticancer chemotherapy. - - 2020-05-31, Grant Agreement signed - - - 2018-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - CylcoRu4PACT - - - H2020-MSCA-IF-2016 - - - 750686 - - - - - UNIVERSITAT DE LES ILLES BALEARS - - - EUR 158 121,60 - - - Gravitational waves from extreme mass-ratio inspirals - - - EUR 158 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - In 2016, the Laser Interferometer Gravitational-Wave Observatory (LIGO) collaboration announced its first ground-breaking detections of gravitational waves sourced by binary black hole mergers. These observations herald the - beginning of a new era in astronomy: gravitational waves are expected to shed light on many unsolved astrophysical and theoretical problems, such as finding neutron stars' equation of state, modelling the formation and evolution of compact objects - and testing alternative theories of gravity. - - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - GWsFromEMRIs - - - H2020-MSCA-IF-2016 - - - 751492 - - - - - POLITECHNIKA WROCLAWSKA - - - EUR 146 462,40 - - - Photo/magnetic stimulated nanocargos for superior cancer treatments - - - EUR 146 462,40 - - - Poland - - - Higher or Secondary Education Establishments - - Breast cancer (BC) accounts for 28 % of the total cancer cases in the European Union (EU) and is the leading cause of cancer-related mortality of European women. The stratification of individual BC sub-types for corresponding - therapy modalities is poor. Therapy outcomes in several BC sub-types are unsatisfactory. Its diagnosis is marred by high proportion of false positives and the economic burden to healthcare systems is very high. To overcome this NANOCARGO will develop - a simultaneous diagnosis and therapy (theranostics) approach based on a multimodal nanocomposite termed as nanocargos. The battle against cancer is much more effectively fought if it is aided by early detection and, potentially concurrent, efficient - treatment. NANOCARGO, introduces a new paradigm that theranostics can be made far more effective if a multimodal action can be integrated by adding a plasmonic shell to a magnetic nanoparticle core. The plasmonic shell can be functionalized with the - chemotherapeutic drugs and aptamars. Magnetic@gold and magnetic@silver type core/shell nanocargos can be conjugated with anticancer aptamer. These nanocargos can be stimulated by simultaneous application of magnetic hyperthermia and photonic therapy. - Cellular delivery can benefit from photoporation. Anticancer therapy can thus be made much more effective through the multimodal actions of these nanocargos exposed to endo-luminal, minimally invasive optical stimulation and extra-corporeal magnetic - resonance imaging based excitation. Such a combined will maximise the delivery of these nanocargos into tumor cells. The magnetic core is advantageous for a controlled delivery of aptamer through an externally applied magnetic field. Gold and silver - shell will support aptamer attachment. X-ray computed Tomography (CT) imaging contrast of absorbing tumors will be better due to higher X-ray absorption of gold and silver. - - 2020-09-30, Grant Agreement signed - - - 2018-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Poland - - - NANOCARGO - - - H2020-MSCA-IF-2016 - - - 751903 - - - - - GOETEBORGS UNIVERSITET - - - EUR 185 857,20 - - - Novel mechanisms of site-specific regulation of bone strength for the prevention of osteoporotic fractures: a translational project - - - EUR 185 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - Osteoporosis is a major health concern characterized by reduced bone mineral density (BMD) and impaired microarchitecture leading to increased risk of fractures and mortality, especially at the hip. At least 40% of women and - 15% of men will sustain one or more fragility fractures in their remaining lifetime, representing a huge economic burden in Europe. Currently available osteoporosis drugs are effective in reducing vertebral fracture risk (dependent on trabecular - bone) while less effective for non-vertebral and hip fracture risk (dependent on cortical bone). This proposal aims to identify novel mechanisms regulating site-specific fracture risk, on the basis of recent human genetic findings on the determinants - of cortical bone thickness (WNT16 locus) and trabecular volumetric BMD (GREM2 locus). This translational research program will study the role of the WNT lipase NOTUM in the regulation of cortical bone thickness via its interaction with WNT16, a key - regulator of cortical bone identified by the proposed supervisor (Nature Medicine 2014). We will next study how the Bone Morphogenetic Protein antagonist GREM2 regulates trabecular BMD. These studies will be performed using genetically modified - murine models and human cell-cultures systems. Finally, in a prospective population-based cohort study (n=3010), we will test if serum level of NOTUM predicts the risk of fractures. Our long term goal is to translate these findings into novel - biomarkers and more effective therapies for the prevention of osteoporotic fractures. - - 2019-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - GOTBONE - - - H2020-MSCA-IF-2016 - - - 750579 - - - - - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - - - EUR 195 454,80 - - - Being precautionary: how rational? How ethical? - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Human decisions can be evaluated on whether they exemplify some precaution. For instance, the mayor was praised for being precautionary in reinforcing the dike along the river. Precaution has recently been raised at the level - of a principle – the Precautionary Principle – which has acquired a widely recognized status in national and international law. This project conducts a philosophical analysis of conceptual and fundamental issues on the Precautionary Principle and on - precaution more generally. I aim at understanding why being precautionary makes sense from a rational viewpoint, both at the individual (Objective A) and collective (Objective B) levels, and from an ethical viewpoint (objective C). - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - Precaution - - - H2020-MSCA-IF-2016 - - - 749425 - - - - - DUBLIN CITY UNIVERSITY - - - EUR 175 866 - - - Development of a Cavity Supported Lipid Membranes Biomimetic drug permeability models (CLIMB) - - - EUR 175 866 - - - Ireland - - - Higher or Secondary Education Establishments - - Permeability Assay (PAMPA) have limited biorelavance and can often be poorly predictive of of drug permeation, particularly for charged species and for complex membranes such as the BBB and particularly of membrane toxicity - which remain key issue leading to high attrition rate and low productivity in the pharmaceutical industry. The proposed fellowship programme aims to address these issues in a very novel way by developing lipid bilayers supported on cutting-edge - Plasmonically-Directed Nano-Structured porous arrays. The substrates prepared via a range of fabrication methods, including 2-photon 3D-nanoprinting, will allow for investigation of drug-membrane interactions, and permeability through a unique and - novel principle, whereby the arrival time of single or few weakly- or non-fluorescent molecules at plasmonic volume in the nano-/micro-cavity is monitored via enhanced spectroscopic technique. Angle dependent Raman microscopy will permit study - independently of the drug-membrane interactions and plasmonic hot spot so both structural and permeation times can be meausered and these studies will be carried out in parallel with Elelctrochemcial impendence spectroscopy of membrane integrity. - This approach will dramatically advance the state-of-the-art in membrane assay. In parallel it provide high quality research training to the MRSA fellow along with, supported by the host institution training programme a range of career promoting - transferable skills acquired. Leading the fellow to a fully-independent academic position. - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Ireland - - - CLIMB - - - H2020-MSCA-IF-2016 - - - 750601 - - - - - KOBENHAVNS UNIVERSITET - - - EUR 200 194,80 - - - The geometry of chromatic categories - - - EUR 200 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - This project studies the local and global structure of fundamental categories in topology, algebra, and algebraic geometry from a geometric point of view. Deep structural results have been proven in special cases, but the lack - of a unified theory has prevented progress on several key conjectures, for example pertaining to local-to-global principles. - - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - ChromoCats - - - H2020-MSCA-IF-2016 - - - 751794 - - - - - UNIVERSITE GRENOBLE ALPES - - - EUR 173 076 - - - Dual capillary waveguide endoscope - - - EUR 173 076 - - - France - - - Higher or Secondary Education Establishments - - Photoacoustic imaging, an emerging multi-wave imaging modality that couples light excitation to acoustic detection via the photoacoustic effect (sound generation via light absorption), relies on detecting ultrasound waves that - are very weakly scattered in biological tissue. It provides acoustic-resolution images of optical absorption non-invasively at large depth (up to several cm). However, ultrasound attenuation increases with frequency, limiting the depth-to-resolution - ratio to about 100. An alternative to overcome the dispersion of light in tissue due to scattering is using thin, micron-sized diameter optical fibers to both deliver and collect light from the sample. A novel idea and preliminary proof-of-concept - experiment has just been demonstrated by Prof. Bossy’s team where a dual waveguide allows also to remotely detect high frequency ultrasound with the same device as that used for guiding light. This device can act both as a multi-mode optical - waveguide for the illumination and fluorescence collection using the outer cladding, and as a waveguide to guide the ultrasound out of the tissue using the core, avoiding the absorption by the tissue and increasing the penetration depth. - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - DARWIN - - - H2020-MSCA-IF-2016 - - - 750420 - - - - - UNIVERSITE DE BRETAGNE OCCIDENTALE - UNIVERSITY OF WASHINGTON - - - EUR 246 668,40 - - - MEchanisms of Coupling of Ocean Dynamics and Intermediate trophic levels: High Resolution study - - - EUR 246 668,40 - - - France - United States - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - "The open ocean is the largest biome on Earth, yet it is the least protected. A major obstacle to its conservation lies in the fine-grained understanding of how marine organisms are affected by the ocean dynamics. In the last - decades remote sensing and bio-logging drastically increased our understanding to how phytoplankton (that can be observed from space as ocean color) and large marine animals (that can be followed with sensors directly attached to them) responds to - oceanic turbulence down to the mesoscale (few weeks-months, 10-100 km). A major knowledge gap still concerns the so-called ""intermediate trophic levels"" (ITLs, i.e. zooplankton and micronekton,) and how mesoscale currents (such as fronts and - eddies) affect them. This is the focus of the MECODIHR project. - - - 2021-09-30, Grant Agreement signed - - - 2018-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - France - - - MECODIHR - - - H2020-MSCA-IF-2016 - - - 749591 - - - - - UNIVERSITY COLLEGE LONDON - - - EUR 183 454,80 - - - Modelling cortical information flow during visuomotor adaptation as active inference in the human brain - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Recent research suggests that to control bodily movements the brain relies on Bayes-optimal predictive models that are updated by sensory prediction error. This assumption may be generalised within a new formal account of - motor control as active (Bayesian) inference. Active inference explains motor control in terms of hierarchical Bayesian filtering or predictive coding, i.e., as belief updating and suppression of prediction error to optimise a hierarchical generative - model in the brain; thereby the weighting of prediction errors by their predicted precision determines their relative impact on hierarchical inference. This novel proposal still lacks concrete empirical investigation. The proposed project will close - this research gap by testing whether cortical information flow during manual actions, requiring visuomotor adaptation and cognitive control of attention, follows the principles of active inference. In two fMRI experiments and one MEG experiment, - participants will move a photorealistic virtual hand model via an MR-compatible data glove to perform simple manual tracking tasks in a virtual reality environment. The precision of prediction errors at multiple levels of a previously established - cortical motor control hierarchy will be experimentally manipulated via visuoproprioceptive conflicts (introduced by delayed visual movement feedback) and via attentional allocation – either stimulus-driven (via increased sensory noise) or endogenous - (instructed) – to visual or proprioceptive movement feedback. Active inference’s specific predictions about information flow between and within cortical areas will be tested with recently established dynamic causal modelling of the modelled - hemodynamic (fMRI) or spectral (MEG) responses. Active inference appeals to a general free-energy principle of brain function; this contribution will thus promote interdisciplinary exchange of knowledge about self- and world-representation in the - brain and will be of general public interest. - - 2019-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ViMoAct - - - H2020-MSCA-IF-2016 - - - 749988 - - - - - UNIVERSITY OF GLASGOW - - - EUR 183 454,80 - - - The World of the Gáidhealtachd and the origins of the Early Modern British State, 1513-1594. - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - By 1603 the political power of the Gaelic world, or Gáidhealtachd, had been broken in the face of the recently created British state. Though certain Gaelic dynasties (i.e., the Campbells and O’Briens) actively worked with the - state, little research has been undertaken on how dynasties such as the O’Donnells and O’Neills possessed the capacity not only to resist but also to threaten this process of state formation throughout the 16th century. Using a series of case studies - and drawing upon a broad base of primary material, this project explores the political and military development of the Gáidhealtachd during two key phases of Anglo-Scottish relations. The first section investigates how certain Gaelic lords - manipulated the course of Anglo-Scottish hostilities from 1513-59 in order to enhance their position within ‘British’ politics. The second section explores how the Gaelic lords reacted to the development of Anglo-Scottish peace and amity from - 1560-94. The main objective of this project is therefore to uncover the basis for the strong level of Gaelic political and military resilience within ‘British’ politics throughout the 16th century and how significant a factor this was in contributing - to the outbreak of the Nine Years War (1594-1603). This is an interdisciplinary project, involving Gaelic, English, Scottish, and Latin historical material as well as elements of literature and archaeology. The project will be strengthened by the - experienced interdisciplinary research team at the University of Glasgow and will involve both the transfer of knowledge to the host institution and the training of the researcher in new competences. Ultimately, this project will make a major - intervention in the history of Early Modern Ireland and Britain and will result in a series of high-impact publications. The proposal also entails a secondment to BBC Scotland and a detailed public engagement strategy aimed at changing public - perceptions of 16th century Ireland and Britain. - - 2020-09-30, Grant Agreement signed - - - 2018-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - GEMS - - - H2020-MSCA-IF-2016 - - - 750447 - - - - - UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6 - - - EUR 173 076 - - - West African Coastal Ocean - Finescale physics, biogeochemistry and climate change - - - EUR 173 076 - - - France - - - Higher or Secondary Education Establishments - - Coastal oceans are essential to our societies but their health status is degrading rapidly in many parts of the world. Anticipating or remedying environmental evolutions/degradations, including those resulting from global - changes, is particularly difficult. This is largely because the knowledge and information we currently have on the ocean functioning do not encompass scales finer than a few tens of kilometers, which is notably insufficient close to shores. WACO will - clarify the role of fine-scale processes (turbulent and wave processes with scales < 10 km) in the present-day functioning and future evolutions of the West African coastal dynamics and biogeochemistry. To do so, it will take advantage of a new - generation of ocean models that is truly apt to simulate coastal dynamics/biogeochemistry/ecosystems in a fully integrated and multi-scale manner. Precisely, the project will be focused on the senegalese and mauritanian coastal oceans from which - state-of-the-art ocean observations are available to complement and evaluate the modelling effort, a robust and interdisciplinary collaborative framework, and unmatched opportunities for social benefits of the research. The project relies on a - massively parallel computing plan that will serve as a demanding training ground for the applicant. Overall WACO will contribute to a deeper understanding of climate change, which is a key goal of EU research. - - 2020-02-29, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - WACO - - - H2020-MSCA-IF-2016 - - - 749699 - - - - - STICHTING NIOZ, KONINKLIJK NEDERLANDS INSTITUUT VOOR ONDERZOEK DER ZEE - - - EUR 165 598,80 - - - SICK OF NOISE - Effects of noise pollution on marine invertebrate health and species interactions - - - EUR 165 598,80 - - - Netherlands - - - Research Organisations - - Noise is considered a threat to human health, causing not only annoyance or hearing impairment but also hypertension, ischemic heart disease and diabetes. Like humans, many animals can be affected by noise. Marine - invertebrates, in particular, can be very sensitive to sounds and, because of their limited mobility, can be exposed to the disturbing noises of boat engines, windfarms and pile drivers over long periods of time. Such underwater noise pollution is - known to have detrimental effects on the activity and physiology of marine invertebrates. - - 2020-07-15, Grant Agreement signed - - - 2018-07-16 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - SICK OF NOISE - - - H2020-MSCA-IF-2016 - - - 750429 - - - - - SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO SANT'ANNA - - - EUR 180 277,20 - - - NON-WESTERN MILITARY INTERVENTIONS AND THE CHARACTER OF WARFARE IN THE EUROPEAN PERIPHERY - - - EUR 180 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - While Western countries regularly intervene militarily abroad, recent years have seen increasing levels of military intervention by non-Western authoritarian and weakly-democratic states in the EU periphery. Non-Western - interventions profoundly impact the security dynamics of an increasingly fragile EU neighbourhood. Despite this, the patterns and character of resulting conflicts are ill-understood, especially compared to recent conflicts involving Western states - (on which much of the recent conflict literature is based). This project will conduct a highly original comparative analysis of three EU-periphery conflicts (Ukraine, Yemen and the West African Sahel) that have seen the involvement of four of the - most militarily active non-Western states in the wider EU neighbourhood (Russia, Saudi Arabia, and Nigeria/Chad respectively). The fellowship will advance knowledge of: 1) how the character of conflict involving non-Western military powers differs - from general conceptualizations of contemporary warfare (and each other); and, 2) how the character of these conflicts is comprehended strategically both by key state actors involved, and by Western security actors (EU and NATO). Such a project is - timely given rising levels of conflict in the EU periphery and necessary given the absence of comparative enquiry into the evolving character of armed conflict across the wider EU neighbourhood. Through a mixed-methods analysis of three conflicts of - critical importance to the EU, this project will offer innovative research findings on the causes, politico-military strategic logics, military practice and potential resolution of contemporary non-Western war that will support the EU’s - recently-developed 2016 ‘Global Strategy’ for the EU Foreign and Security Policy. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - NWICWEP - - - H2020-MSCA-IF-2016 - - - 748164 - - - - - UNIVERSITY COLLEGE LONDON - - - EUR 183 454,80 - - - Looking at it from a different angle: The role of viewpoint-dependency in traumatic intrusions. - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Many victims of psychological trauma suffer from recurrent intrusive trauma memories. According to Dual-Representation Theory (DRT), intrusive memories reflect functional deficiencies in the brain’s hippocampal system, which - fails to translate the egocentric perceptual impressions of the trauma into viewpoint-independent (or allocentric) spatial representations. This proposal tests this assumption and explores allocentric memory training as a potential novel intervention - against intrusive memories. - - 2020-03-31, Grant Agreement signed - - - 2018-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - TRAUMA_CONTEXT - - - H2020-MSCA-IF-2016 - - - 749206 - - - - - FUNDACIO CENTRE DE REGULACIO GENOMICA - - - EUR 170 121,60 - - - Exploring terra incognita: terrestrialization of arthropods in the era of genomics - - - EUR 170 121,60 - - - Spain - - - Research Organisations - - Terrestrialization – the colonization of the land habitat by plants and animals – is amongst the most important events in the history of life on Earth. Understanding terrestrialization is, therefore, key to understanding - biological adaptation. From all animals, arthropods constitute the most successful phylum, manifest in extreme species richness and successful radiation into nearly every ecological niche. Arthropods colonized the land multiple times independently - and at different times in Earth history, with terrestrial arthropods massively outnumbering the aquatic ones. This begs the questions how, when, why and how often did arthropods become successful in the terrestrial environment, constituting ideal - model systems to study terrestrial adaptations at the genomic, physiological and morphological levels. In order for animals living in aquatic environments to colonize land, a number of physiological barriers need to be overcome, including massive - changes to methods of respiration, water management and osmoregulation, reproduction or digestion, among others. Water balance is one of the main challenges facing primarily terrestrial animals. Osmoregulation is also highly relevant to the question - about the route taken onto land, specifically whether the ancestors of a given terrestrial arthropod group came directly from a marine environment or via fresh water. The main goal of this project is to shed light on the mode and tempo of these - changes through the integration of phylogenomics, paleontology and comparative genomics and transcriptomics. For this, I propose to investigate i) the genetic basis of cuticular composition in marine and terrestrial arthropod lineages, ii) - characterization of genes involved in osmoregulation, and iii) lineage-specific orphan gene families that could have contributed to arthropod evolvability in terrestrialization events. The results of this project will allow an unprecedented - understanding of deep-time questions in arthropod evolution. - - 2020-01-14, ongoing project - - - 2018-01-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Spain - - - TERRESTREVOL - - - H2020-MSCA-IF-2016 - - - 747607 - - - - - UNIVERSITY OF DURHAM - - - EUR 183 454,80 - - - Managing Risk in Early Complex Societies in Syria-Palestine: An Investigation of Changing Animal Herding Strategies through the 4th-2nd Millennia BC Using Multi-Element Isotopic Analysis - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The proposed research at Durham investigates the role of pastoral mobility in the rise of urban societies and large, integrated supra-regional economies in western Syria during the 3rd millennium BC through isotopic analysis - of skeletal remains. During this period, state-level political systems developed and there was a massive expansion of urban settlement into the arid Syrian steppe. Scholars at Durham have proposed that elite exploitation of the economic opportunities - provided by the humble sheep for the development of a vast new livestock-based economy lay at the heart of this transformation, representing a fundamental shift in socio-political networks, economic resilience and risk management strategies. Although - material culture and texts provide clear indications about the vital significance of the wool industry in these major socio-economic changes, the proposed research will provide the first reliable means of directly testing these hypotheses by using - multi-element isotopic analysis of archaeological animal enamel and bone to examine changes in animal management and herding strategies in Syria-Palestine in the 4th-2nd millennia BC. Two case studies will represent areas close to the core of this - emerging system of economic intensification, and more peripheral areas that were likely impacted by these changes in more subtle ways. - - 2020-07-31, Grant Agreement signed - - - 2018-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - MRECS - - - H2020-MSCA-IF-2016 - - - 749872 - - - - - UNIVERSIDAD PABLO DE OLAVIDE - - - EUR 158 121,60 - - - On the Frontiers of Peace. Cross-cultural Peacebuilding on the Global Frontiers of the Iberian Empires (1500-1580) - - - EUR 158 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - This research project investigates the historical roots of cross-cultural peacebuilding. European expansion during the sixteenth century was characterised by a high degree of violence, which was fuelled by cultural differences - and religious radicalisms. The meeting of different cultures created new forms of violence, but, at the same time, generated new forms of cross-cultural encounters that were driven to construct a lasting peace. This project explains the transition - from the violent conflicts of the first encounters between Europeans and non-European peoples, to their peaceful coexistence. Rather than focusing on cross-cultural diplomacy or treaty-making, this research project explains how peace was constructed - “on the ground”. In order to do so, it focuses on three different frontiers of the first global empires. - - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - FRONTIERPEACE - - - H2020-MSCA-IF-2016 - - - 748592 - - - - - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - - - EUR 173 076 - - - Syntenin-phosphatidic acid interaction in exosome biogenesis and cell-cell communication: a structure-function based approach - - - EUR 173 076 - - - France - - - Research Organisations - - Cells communicate with their environment in various ways, including by secreting vesicles. Some of these extracellular vesicles originate from endosomes, are loaded with proteins, lipids and RNAs and are called exosomes. - Exosomes emerge as important players in physiological cell-cell communication, but also in various systemic diseases. Understanding how cells control the selective incorporation of ‘messages’ in their exosomes is thus essential, and such fundamental - new knowledge may allow us to better understand cancer spread for example. Recently syntenin, a small intracellular adaptor protein, was identified as essential for the biogenesis of presumably a distinct class of exosomes that might be important for - cancer cell communication and systemic invasion. Based on preliminary work, this study aims to evaluate the role of the membrane lipid phosphatidic acid in the formation of syntenin exosomes, their loading with cargo and their function in - intercellular communication. A structure-function based approach is used, allowing if successful to pave the way for rational and innovative drug intervention. The fellowship will offer the applicant the possibility to receive an intensive training - in biochemistry, cellular, molecular biology and drug discovery as well as to acquire important secondary skills which will pave the way for his career as an independent researcher. - - 2020-11-30, Grant Agreement signed - - - 2018-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - EXOGENESIS - - - H2020-MSCA-IF-2016 - - - 747025 - - - - - UNIVERSITY OF DUNDEE - - - EUR 195 454,80 - - - Unravelling the effect of origin number on the success of genome replication - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - DNA replication must be regulated in eukaryotic cells to ensure that the genome is precisely duplicated. The process is split into two non-overlapping stages: origin “licensing” and origin “firing”. During licensing in G1, ORC - loads MCM2-7 onto DNA, and during the firing stage in S phase MCM2-7 is activated to drive replication forks. To prevent re-replication of DNA no new origins must be licensed once S phase begins. Since replication forks can irreversibly stall, it is - crucial that sufficient origins are licensed before S phase entry. The “licensing checkpoint” prevents cells in G1 with too few licensed origins from entering S phase. A number of different MCM and ORC mutations have been identified, leading to - cancer susceptibility, proliferation defects and/or developmental abnormalities. However, it is hard to explain the spectrum of defects caused by specific mutations, such as in Meier-Gorlin Syndrome. In this project, I will use genome editing to - engineer iPS cells with specific mutations in MCM and ORC proteins to determine the effects on origin licensing, licensing checkpoint activation and genome stability. I will use state-of-the-art quantitative proteomics, next generation sequencing and - flow cytometry to unravel the molecular mechanisms underpinning the licensing checkpoint and to define the core molecular pathways that coordinate DNA replication and the cell cycle. A comparison of the effect of ORC and MCM mutations in - clinically-relevant cells derived from iPSCs and in cancer cell lines will allow me to understand cell-type specific differences in regulation of DNA replication and explain the effects of these mutations on human patients. These new results will - open new possibilities to develop specific anti-cancer drugs against selected components of the licensing checkpoint system. Moreover, it will allow me to merge neurodevelopment, DNA replication, stem cell biology and cancer research, laying the - foundations upon which to build my future career. - - 2019-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ORI NUMBER - - - H2020-MSCA-IF-2016 - - - 746908 - - - - - BOURNEMOUTH UNIVERSITY - - - EUR 183 454,80 - - - Artistic Animation Rendering with Stylization - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Computer animation is a key technology for the creative industries and has strong links to many key sectors of digital economy, including gaming and post-production. Its annual global market value is €200 billion and it is - growing 7% annually. Although the European Commission has established policies and initiatives for creative industries, 60% of the global animation market is shared between the US (supported by strong finance and advanced technology) and the - Asia-Pacific countries (bolstered by low labour costs). To gain market share in computer animation, the EU needs novel technologies that can produce rich content and special effects at a competitive price. This fellowship project describes how novel - Animation Stylization Techniques (ASTs) can be developed to enrich content without high labour costs, by bringing to the UK a high calibre researcher with 9 patents and 28 publications. - - 2019-10-19, ongoing project - - - 2017-10-20 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - AniStyle - - - H2020-MSCA-IF-2016 - - - 747439 - - - - - UNIVERSITEIT UTRECHT - - - EUR 177 598,80 - - - Novel multivariate, high-resolution mapping of the exposure of ecosystems to climate and land use change - - - EUR 177 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - To protect and preserve natural habitats, we urgently need integrated assessment methodologies. Current conservation-oriented assessments of ecological vulnerability rely upon the identification and quantification of the - effects from of the most important drivers of change. However, accurate predictions and practical solutions have proved difficult to formulate as most works at global or continental scales have only focused on climatic changes, disregarding important - factors such as land use change. CLIMLAN will address this shortcoming using an integrated assessment that combines two of the most important drivers of biodiversity change today: climate and land-use change. Here I will answer two original and - important questions: (1) which are the most useful indices for measuring and mapping the ecological vulnerability to future environmental change?; and (2) is there a mismatch between current management and planning strategies and ecological - vulnerability to projected environmental changes? For this, I will focus on measuring and mapping both climate and land use changes over time, and assessing how such changes match both ecosystem vulnerability and current conservation practices. A - lasting product of CLIMLAN will be a readily applicable open access spatially explicit methodology and an online mapping tool, to measure and spatially display ecosystem vulnerability to environmental changes. These tools will allow a better - assessment of the current and expected effects of changing environmental conditions on conservation areas, and will facilitate targeted management guidelines and improved adaptation strategies. - - 2020-04-01, Grant Agreement signed - - - 2018-04-02 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - CLIMLAN - - - H2020-MSCA-IF-2016 - - - 748753 - - - - - THE GLASGOW CALEDONIAN UNIVERSITY - - - EUR 195 454,80 - - - GET READY - a unique intervention addressing activity reduction co-designed with Care Home residents and University students, following a service-learning methodology - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The ‘Get Ready’ project aims to integrate service-learning methodology into Physical Therapy and Sport Sciences University degrees by offering students individual service opportunities (placements) with Residential Care Homes, - in order to co-create the best suited physical activity (PA)/ sedentary behaviour (SB) intervention with researchers, older adults (end-users) in care homes, health professionals and policy makers. The project will use a Participatory Action Research - (PAR) methodology and will follow the objectives of workforce development to support users to demand more responsive and integrated care programmes for chronic diseases, and to involve end-users in their health management and decision-making relevant - to their own health (Action Area 6). We will use mixed methods to assess the intervention feasibility and acceptability (including process evaluation) and we will conduct a pilot study of a two armed pragmatic randomized controlled trial to assess - the effectiveness of a 12-week complex intervention on reducing SB and increasing PA, infused with behaviour change technologies, in an institutionalized older population. This complex intervention co-designed with care home residents and conducted - by university students will be compared to existing PA interventions (usual care), conducted by health professionals working in the Residential Care Homes. The experienced researcher will significantly expand her scientific knowledge by combining it - with the new themes of SB as a risk factor for health and its assessment in institutionalized older adults, shorten the gap between students and real life conditions, and the process of PAR methodology to co-create a robust intervention through - workforce development with end-users, providing a logical progression and extension of her knowledge, enhancing the experienced researcher’s academic skills and offering a distinct progression on wider academic (as opposed to purely research) skills. - - 2020-01-21, ongoing project - - - 2018-01-22 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - GET READY - - - H2020-MSCA-IF-2016 - - - 747490 - - - - - UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN - - - EUR 175 866 - - - Nanoparticle Biointerface Mapping - - - EUR 175 866 - - - Ireland - - - Higher or Secondary Education Establishments - - The Nanoparticle Biointerface Mapping project builds on the extensive bionano interactions research in the group of Professor Kenneth Dawson at University College Dublin. In the NanoBioMap project I propose a cutting-edge - interdisciplinary approach to develop a versatile tool allowing me to obtain detailed 3D maps of biomolecules at the surface of nanoparticles in complex biological media and study their importance for cell interactions. I will build on my extensive - knowledge of nanomaterial science to develop this 3D mapping tool combining a tailor-made library of antibody-tagged quantum dots with electron microscopy 3D image reconstruction and X-ray elemental mapping. The resulting versatile method has - multiple uses far beyond analyzing protein coronas. I envision applications of this state-of-the-art mapping tool in areas such as vaccine development, enzymatic catalysis on supported particles, cancer treatment and tracking of pollutants in water - flows. - - - 2020-09-30, Grant Agreement signed - - - 2018-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Ireland - - - NanoBioMap - - - H2020-MSCA-IF-2016 - - - 743605 - - - - - THE UNIVERSITY OF BIRMINGHAM - - - EUR 195 454,80 - - - Effect of rare-earth doping elements on the mechanical and oxidation resistance performance of silicon carbide coated carbon fibre / zirconium carbide composites for high temperature applications - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - There is an increased demand for high temperature structural materials suitable for use at>1400°C, including heat exchangers, Generation IV nuclear reactor components (e.g. control rod sheath & fuel constituents), the - receiver materials of concentrated solar power (CSP) systems, high temperature thermoelectric devices and static components in gas turbines and aero engines. Ultra-high temperature ceramics (UHTCs) exhibit especially high melting temperatures and - include the diborides and carbides of zirconium and hafnium (ZrC & HfC). Unfortunately, UHTCs also suffer from poor fracture toughness, relatively poor oxidation resistance and are very difficult to process since the densification temperature - required is also very high. EREMOZ will address these challenges by using a non-conventional process route along with a combination of fibre reinforcement and rare earth dopants. Specifically, processing will be based on the energy efficient process - of chemical vapour infiltration (CVI) rather than more conventional sintering; the former allows dense composites to be produced at much lower temperatures. The poor fracture toughness will be improved by the introduction of silicon carbide fibres - (SiCf) or carbon fibres (Cf), which enhance resistance to crack propagation. Finally, oxidation resistance will be improved by the introduction of second phases, such as those based on silicon and/or rare earths, which facilitate the formation of - oxide scales that inhibit oxygen diffusion. The outcomes from this project will be three fold, to: - - - 2020-03-31, Grant Agreement signed - - - 2018-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - EREMOZ - - - H2020-MSCA-IF-2016 - - - 748568 - - - - - CENTRE EUROPEEN D'ETUDE DU DIABETE - - - EUR 185 076 - - - Cross-talk between skeletal muscle and pancreatic islets: impact of exosomes - - - EUR 185 076 - - - France - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The worldwide explosion of obesity has resulted in an ever-increasing prevalence of type 2 diabetes (T2D), a non-communicable disease that affects more than 370 million people worldwide. T2D is characterized by insulin - resistance with a relative deficiency in insulin secretion. It is now recognized that there is decreased beta-cell function and mass in T2D but the precise underlying mechanism remains to be determined. Skeletal muscle accounts for >50% of the - total glucose uptake in the post-prandial state, it is also the largest organ in non-obese individuals. Recent studies demonstrated that there is conversation between skeletal muscle and beta-cells, and that certain peptides (i.e. myokines) secreted - by insulin-resistant skeletal muscle cells may impact negatively on beta-cell function, proliferation and survival in T2D. Nevertheless, other factors than myokines could also be involved in this inter-organ communication. A novel concept suggests - microvesicles, such as exosomes, as a new cell-to-cell communication mode. The major goal of the project will be to characterize the different exosomes populations and their impact on islets cells. The findings may have important implications for - understanding decreased functional beta-cell mass in diabetes, especially in T2D etiology, and therefore bring new insights into the development of innovative therapies. - - - 2020-01-01, ongoing project - - - 2018-01-02 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-SE - Society and Enterprise panel - - - France - - - ExoDia - - - H2020-MSCA-IF-2016 - - - 753670 - - - - - KOBENHAVNS UNIVERSITET - - - EUR 200 194,80 - - - Structure and classification of C*-dynamics - - - EUR 200 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - We study group actions on C*-algebras from a structure and classification point of view, importing concepts from the Elliott classification program into the equivariant context. The challenge is to advance the structure theory - for natural classes of actions of amenable groups on C*-algebras. In a similar vein, we shall consider flows on C*-algebras, which are the mathematical abstractions of time evolutions. The objectives of this proposal are: - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - SCCD - - - H2020-MSCA-IF-2016 - - - 746272 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 183 454,80 - - - Endoplasmic reticulum structure and synaptic function in Drosophila - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - In neurons, endoplasmic reticulum (ER) organelle shows physical continuity between dendrites, cell body and axonal presynaptic terminals, and has been termed “a neuron within a neuron”. The importance of ER in axons is - suggested by the fact that mutations of ER-shaping proteins result in hereditary spastic paraplegia (HSP), a motor axon degeneration disease. ER is present in presynapses, and mutations of ER-shaping proteins disrupt synaptic morphology or function. - However, the physiological roles of ER distribution in this context are largely unknown. - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SynapseER - - - H2020-MSCA-IF-2016 - - - 745007 - - - - - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - - - EUR 183 454,80 - - - Exact Results in Extended Holography - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The study of integrable models in the AdS/CFT correspondence has provided deep insights into string theory, the holographic principle, and the finite coupling behavior of quantum field theory. My proposal aims to extend - aspects of this approach beyond supersymmetric and conformal theories by studying integrable deformations of the AdS5 x S5 superstring. These come in two types — quantum deformations and Drinfeld twists — which can produce both new theories and new - perspectives on well-established ones. The aims of this programme are (A) to understand quantum deformations in string theory and AdS/CFT, (B) to refine associated technical tools based on integrability, (C) to develop a unified perspective on - Drinfeld twists in string theory and AdS/CFT, and (D) to overcome technical obstacles in the integrability based description of twisted models. By developing exact results and methods, this programme will lead to new insights in string theory, - holography, and quantum field theory, at finite coupling, beyond the superconformal regime. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ERIEH - - - H2020-MSCA-IF-2016 - - - 744150 - - - - - MEDIZINISCHE UNIVERSITAET WIEN - - - EUR 178 156,80 - - - Learning and PREdiction based on the PREnatal CONnectome FInGerprint - - - EUR 178 156,80 - - - Austria - - - Higher or Secondary Education Establishments - - "Endeavours towards a more profound understanding of the neural architecture enabling the staggering cognitive abilities of the human brain hold high promises regarding diagnosis and treatment of various diseases affecting the - neural system. The novel paradigm of brain connectomics has opened a wealth of insights into the individual differences, emergence, development, plasticity and disease specific re-organization of macro-scale brain networks composed by interconnected - and synchronously operating neural units. - - 2020-11-22, Grant Agreement signed - - - 2018-11-23 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Austria - - - PRECONFIG - - - H2020-MSCA-IF-2016 - - - 747831 - - - - - UNIVERSITY COLLEGE LONDON - - - EUR 195 454,80 - - - How visual perception shapes our cities: a cognitive model of ageing population - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Two mega-trends – the rapid urbanisation of the world’s population and the ageing of that same population – will soon collide. Adapting to the challenges of elderly citizens (many of whom no longer drive), urban designers need - appropriate tools to support planning for walking, the most environmentally, socially, and economically sustainable transport mode. Cities’ walkability depends not only on physical settings, but also on processes of human spatial cognition, in - particular visual perception. However, current state of art methods in modelling and forecasting urban systems are based mainly on economic and transportation demands and ignore pedestrians’ spatial cognition. This research discovers how - visuo-spatial cognition contributes to the generation of new urban uses and activities based on the age profile of the user population. It constructs a novel urban-behavioural paradigm that links built environment and the way people use it, by - addressing three fundamental questions: (1) What are the most important visuo-spatial properties influencing pedestrian cognition? (2) How urban visibility could be encoded and analysed as an abstracted spatial representation (visibility network)? - (3) What mechanisms allow cities to be generated through feedback reflected in pedestrian movement and urban visibility? These questions are answered using an interdisciplinary approach: It combines quantitative techniques for spatial modelling with - qualitative strategies for tracing of pedestrian behaviour in Immersive Virtual Reality (IVR). The research findings will set a framework for the evidence-based tool to assist planners, architects and stakeholders in the design and evaluation of - urban projects in view of the changing needs of urban population. - - 2020-09-30, Grant Agreement signed - - - 2018-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - AgeCogCity - - - H2020-MSCA-IF-2016 - - - 744835 - - - - - UNIVERSITY OF GLASGOW - - - EUR 195 454,80 - - - INtelligeNt ApplicatiOns oVer Large ScAle DaTa StrEams - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Large scale data analytics is the key research domain for future data driven applications as numerous of devices produce huge volumes of data in the form of streams. Analytics services can offer the necessary basis for - building intelligent decision making mechanisms to support novel applications. Due to the huge volumes of data, analytics should be based on efficient schemes for querying large scale data partitions. Partitions contain only a piece of data and a - dedicated processor manages the incoming queries. The management of continuous queries over data streams is a challenging research issue requiring intelligent methods to derive the final outcome (i.e., query response) in limited time with maximum - performance. The management process of continuous queries involves their assignment to specific processors and the processing of the derived responses. We focus on a group of query controllers serving the incoming queries and, thus, becoming the - connection of big data systems with the real world. INNOVATE proposes solutions for the management of the controllers behavior. We propose an intelligent decision making process for each controller in three axes: (i) top-down, by realizing a - mechanism that assigns queries to the underlying processors; (ii) bottom-up, by proposing decision making mechanisms for returning responses to users/applications on top of early results; (iii) horizontal, by proposing optimization schemes for - queries management. We adopt a pool of learning schemes and an ensemble learning model dealing with how and on which processors each query should be assigned. We also propose specific schemes for combining processors responses. Intelligent and - optimization techniques are adopted for the controllers group management. Machine learning, Computational Intelligence and optimization are the key adopted technologies that, when combined, provide efficient solutions to a challenging problem like - the support of intelligent analytics over big data streams. - - 2020-03-31, Grant Agreement signed - - - 2018-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - INNOVATE - - - H2020-MSCA-IF-2016 - - - 745829 - - - - - BILKENT UNIVERSITESI VAKIF - - - EUR 157 845,60 - - - Nanoscale Vertical Cavity Surface Emitting Laser and its Arrays - - - EUR 157 845,60 - - - Turkey - - - Higher or Secondary Education Establishments - - Significant advances are needed to improve the speed and efficiency of future communication and computing systems. Photonic interconnect components are the only solution to offer both high speed and low power consumption. To - this end, vertical-cavity surface-emitting lasers (VCSELs) have been widely deployed as optical interconnects in the last two decades. Even though the current VCSEL technology has been very successful, its processing approach has been proven to be - particularly challenging for miniaturization, it reduces the reliability for small lasers and its high thermal resistance substantially degrades the lasers’ performance. This project addresses all these bottlenecks by focusing on the development of a - nanoscale VCSEL (NOVEL) device for ultra-low threshold, energy efficient and ultra-fast operation for future optical interconnects and light sources. - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Turkey - - - NOVEL - - - H2020-MSCA-IF-2016 - - - 745598 - - - - - UNIVERSITEIT VAN AMSTERDAM - UNIVERSITEIT VAN AMSTERDAM - - - EUR 2 498 328 - - - Understanding the Stability and Plasticity of Emotional Memory - - - EUR 2 498 328 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The breakthrough discovery in animal research that fear memories may change upon retrieval – referred to as memory reconsolidation – has drastically changed the view on the malleability of emotional memory. Inspired by these - insights, we have developed a novel approach to pharmacologically erase the affective component from fear memories in humans. Although these findings suggest a paradigm shift in clinical practice, there are many fundamental questions to be resolved. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Netherlands - - - ErasingFear - - - ERC-2016-ADG - - - 743263 - - - - - ECOLE D'ECONOMIE DE PARIS - ECOLE D'ECONOMIE DE PARIS - UNIVERSITY COLLEGE LONDON - - - EUR 1 523 217 - - - Learning through Categories in Social and Economic Interactions - - - EUR 1 523 217,01 - - - France - France - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The analogy-based expectation equilibrium (Jehiel, 2005) has been introduced to cope with strategic environments in which agents form their expectations by bundling data that come from different sources (see also the valuation - equilibrium defined in Jehiel and Samet, 2007). An essential next step is to make progress on when and how subjects bundle data to facilitate learning. Various principles are proposed to discipline the choices of analogy partitions in ABEE and of - similarity classes in VE: the observation-based principle views the bundling as a consequence of a lack of accessibility to missing information in past interactions, the psychologically-based principle views categorizations as the consequence of - observed similarity in early interactions, the culturally-based principle views the bundling of actions into similarity classes either as a consequence of a common labelling of actions or as a consequence of ethical considerations that lead us to - think of different actions as having similar consequences. The impact of such principles will be studied both theoretically and experimentally with the goals of explaining a number of new phenomena and shifting the conventional wisdom in behavioural - economics that has pointed out a number of anomalies in behaviors without systematically relating them to imperfections in the learning process. In addition, I will be concerned with the aggregation of different types of feedback such as data on one - own performance or data on others’ attitudes in multi-context environments, as well as putting the proposed approach of learning through categories in the broader perspective of the literature on bounded rationality - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - France - - - LTCSEI - - - ERC-2016-ADG - - - 742816 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 195 454,80 - - - Nitric oxide regulation of repolarisation in the heart: role of mechanical stress - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Atrial fibrillation (AF) is a leading risk factor for stroke and is a growing public health burden. The condition is associated with pronounced electrical remodelling of the atria and can prove challenging to treat. A - potential target for AF therapies is the repolarising potassium current IKur, carried by the atrial specific ion channel Kv1.5. This channel is not found in the ventricles and therefore provides an attractive therapeutic target for the treatment of - AF. In atrial myocytes isolated from patients in AF we have shown an increase in IKur, as well as a reduction in the expression of neuronal nitric oxide synthase (nNOS). Inhibition of nNOS in mycoytes from patients in sinus rhythm recapitulated the - AF phenotype. Kv1.5 is also modulated by mechanical stress, which has been shown to affect NO production in myocytes. We have shown that shear stress recruits Kv1.5 from an intracellular pool to the cell surface, leading to an increase in IKur. This - proposal aims to investigate mechanism by which nNOS regulates IKur. We hypothesise that mechanical stress (likely modified in AF) will result in altered nNOS regulation of Kv1.5 in human myocytes. We will go on to investigate how nNOS regulation of - Kv1.5 is dysregulated in AF. A multi-disciplinary approach will be used employing a) human mycoytes isolated from patients, b) an nNOS knockout (-/-) mouse and c) cardiomycoytes overexpressing GFP-Kv1.5. Whole cell currents from isolated myocytes - will be measured electrophysiologically, and IKur pharmacologically dissected. A range of biochemical techniques will be employed to investigate the physical interactions between nNOS and Kv1.5. Conventional and TIRF microscopy will be used to - examine the localisation of Kv1.5 and partner proteins when nNOS activity is inhibited, or where the nNOS protein is absent (nNOS-/-). This translational study will improve our understanding of ion channel regulation in AF and may identify important - new targets for AF therapies. - - 2020-10-30, Grant Agreement signed - - - 2018-10-31 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - NO-STRESS - - - H2020-MSCA-IF-2016 - - - 746208 - - - - - KAROLINSKA INSTITUTET - KAROLINSKA INSTITUTET - - - EUR 2 149 227,50 - - - A Functional, Mature In vivo Human Ventricular Muscle Patch for Cardiomyopathy - - - EUR 2 149 227,50 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Developing new therapeutic strategies for heart regeneration is a major goal for cardiac biology and medicine. While cardiomyocytes can be generated from human pluripotent stem (hPSC) cells in vitro, it has proven difficult to - use these cells to generate a large scale, mature human heart ventricular muscle graft on the injured heart in vivo. The central objective of this proposal is to optimize the generation of a large-scale pure, fully functional human ventricular muscle - patch in vivo through the self-assembly of purified human ventricular progenitors and the localized expression of defined paracrine factors that drive their expansion, differentiation, vascularization, matrix formation, and maturation. Recently, we - have found that purified hPSC-derived ventricular progenitors (HVPs) can self-assemble in vivo on the epicardial surface into a 3D vascularized, and functional ventricular patch with its own extracellular matrix via a cell autonomous pathway. A - two-step protocol and FACS purification of HVP receptors can generate billions of pure HVPs- The current proposal will lead to the identification of defined paracrine pathways to enhance the survival, grafting/implantation, expansion, - differentiation, matrix formation, vascularization and maturation of the graft in vivo. We will captalize on our unique HVP system and our novel modRNA technology to deliver therapeutic strategies by using the in vivo human ventricular muscle to - model in vivo arrhythmogenic cardiomyopathy, and optimize the ability of the graft to compensate for the massive loss of functional muscle during ischemic cardiomyopathy and post-myocardial infarction. The studies will lead to new in vivo chimeric - models of human cardiac disease and an experimental paradigm to optimize organ-on-organ cardiac tissue engineers of an in vivo, functional mature ventricular patch for cardiomyopathy - - 2022-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Sweden - - - 5D Heart Patch - - - ERC-2016-ADG - - - 743225 - - - - - UNIVERZA V LJUBLJANI - UNIVERZA V LJUBLJANI - - - EUR 2 266 067 - - - Post-war trasistions in gendered perspective: the case of the North-Eastern Adricatic Region - - - EUR 2 266 067 - - - Slovenia - Slovenia - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The EIRENE project’s purpose is to think afresh 20th-century post-war transitions by taking into account a gendered perspective. Namely, the historiographic consideration of gender thoroughly alters the understanding of social - dynamics in multi-ethnic areas during the post-war transitions. They will be observed in the North-Eastern Adriatic region, an overlooked European space, marked by border redefinitions, changes of political systems, and high interethnic conflict - intensity, but also by genuine cooperation among ethnic groups. The region has all the qualities of a “laboratory environment” for the study of gender positions and interrelations after World Wars I and II and after the Yugoslav wars in the 1990s. - The project will differ substantially from previous attempts to analyse post-war transitions in these aspects: a) longitudinal approach, comparing three post-war periods in order to detect their specifics and (dis)continuities; b) transnational - approach, by overcoming nation-centric frameworks of analysis; c) by combining conceptual political and social sciences with historiography; and finally, d) by examining post-war transitions through the prism of gender. Focusing on four - research-fields (politics, political violence, work, family), the project will validate innovative analytical concepts of the “inclusion-exclusion paradox” of women in post-war transitions, and women as “cross-boundary mediators”. Within the category - of gender, focal attention will be given to women as they are often invisible in historical accounts and remain neglected in historicizing. By aggregating empirical sources, the project will approach the proposed subject matter by investigating the - processes of identification across the lines of ethnic origin, class, generations, marital status, profession/occupation, language of use, migratory processes, etc. The project’s added value is its novel conceptual applicability to other comparable - geopolitical areas. - - 2022-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Slovenia - - - EIRENE - - - ERC-2016-ADG - - - 742683 - - - - - UNIVERSITAT DE BARCELONA - UNIVERSITAT DE BARCELONA - - - EUR 2 199 318 - - - Moments in Time in Immersive Virtual Environments - - - EUR 2 199 318 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project investigates how virtual reality (VR) can be used to live through an historical event so that participants perceive themselves to be there (Place Illusion) and take the events that are happening as real - (Plausibility). To provide an application focus the research will be constructed around recreating a famous rock concert from the 1980s. The specific elements of the research involve an Agent Based Model (ABM) that populates the environment with - thousands of virtual characters with their behaviour driven by the music. This ABM will run in VR embedding participants as a type of agent. Agents will have personality and emotional state that can influence one another, and the actions and state of - participants will also influence the unfolding of the model. Based on the predictive coding model of brain functioning a theory of Place Illusion will be developed that results in a universal measurement. Similarly, the Plausibility Illusion will be - modelled and corresponding universal measure derived. Participants in VR will be embodied, so that they will have a first person perspective life-sized virtual body that moves as they do. We will exploit the concept of body ownership and its - consequences for attitudinal, behavioural, cognitive and agency changes to give people unique experiences of the virtual events, and carry out a series of experiments to assess the influence of being transported back in time in a younger body has on - ageing. Our recent discovery that illusory agency can be realised through virtual embodiment will be used for research on improved motor learning. To allow people to move through the environment we will investigate paradigms for virtual walking, and - in particular whether the multisensory principles involved in body ownership illusions can be used to lessen simulator sickness. The long term goal of the project is to understand how to capture treasured past moments lost in time, through their - reproduction in ABM inspired virtual reality. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Spain - - - MoTIVE - - - ERC-2016-ADG - - - 742989 - - - - - UNIVERSITETET I OSLO - - - EUR 208 400,40 - - - Spectra of Molecules in Strong Magnetic Fields - - - EUR 208 400,40 - - - Norway - - - Higher or Secondary Education Establishments - - Electronic spectroscopy is one among several types of spectroscopy employed to study molecules in stellar objects. Strong magnetic fields, as in white-dwarfs and neutron stars, can severely distort these spectra. To accurately - interpret the data, we must understand the forces shaping the spectra in situations so far removed from terrestrial conditions. Such strong fields also imply a breakdown of the perturbative mechanism commonly used for studying magnetic phenomena in - the pertinent regimes on earth. We shall focus on the intermediate regime of field strengths (~10^5 T), where, neither the magnetic field nor the inter-particle interaction can be treated as a perturbation leading to novel physics and chemistry, that - remains little explored for molecules. This project seeks to develop the methodology to compute excitation energies and potential energy surfaces in the presence of strong uniform and non-uniform magnetic fields, included non-perturbatively, at - varying levels of theoretical complexity (Hartree-Fock, Density Functional Theory, Random Phase Approximation, SRCC and MRCC) and study the distortion of these spectra across a range of magnetic field strengths. We shall focus on analysing the source - of these distortions at the microscopic level, ie. which of orbital effects, spin effects, correlation effects and relativistic effects play the determining role. This project is multidisciplinary using principles of quantum chemistry in tackling - astrochemical problems. The study is fundamental and is expected to reveal interesting results relevant even for the weaker fields on earth. The benchmarking of the standard DFT exchange-correlation functionals against CC in the regime of strong - magnetic fields will have a long-term impact as most existing DFT approximations have been formulated within DFT or collinear spin DFT (SDFT); practical DFT functionals to describe molecules in magnetic fields (e.g. at the CDFT or non-collinear SDFT - level) are much less developed. - - 2020-09-30, Grant Agreement signed - - - 2018-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Norway - - - MAGSPEC - - - H2020-MSCA-IF-2016 - - - 745336 - - - - - KOBENHAVNS UNIVERSITET - - - EUR 212 194,80 - - - Land Use and Climate Change Attribution for biodiversity impact assessments - - - EUR 212 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - Across the globe, species are shifting their distributions to track the warming temperatures, and habitat conversion is reducing species diversity. However, while both climate and land use change are recognized as top threats - to biodiversity, studies on their synergistic effects are very rare. This is at least partly due to 1) a lack of consistent definitions and measures of land use change that can be directly related to biodiversity responses, and 2) difficulties in - attributing change to either driver because of correlations, scale-dependencies, and interaction effects between the two. This project will develop a framework for separating the effects of land use and climate change on biodiversity using a range of - methodologies such as meta-analysis, fieldwork, and modeling. The project will assess the land use definition and driver attribution challenges in the past literature, explore the potential of high-resolution remote sensing products and Google Street - View to measure land use changes, and use unprecedented long-term monitoring citizen science programs to disentangle impacts of land use and climate change on bird populations as a case study. The Fellowship is a timely answer to recent calls to - account for multiple environmental change drivers and improve our predictive ability of future biodiversity changes. The outputs will be of relevance for conservation management and policymaking in the EU and beyond. The host institute (CMEC) is at - the forefront of macroecology and climate change research, and will give me access to worldwide experts in areas directly relevant to the project. The research and training opportunities offered by CMEC will broaden my field of study and strengthen - my analytical and teaching skills – crucial for helping me establish an independent research career and become a leading figure within the field of integrative global change ecology in Europe. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - LUCCA - - - H2020-MSCA-IF-2016 - - - 746334 - - - - - UNIVERSITA DEGLI STUDI DI MILANO - UNIVERSITA DEGLI STUDI DI MILANO - FONDAZIONE ISTITUTO NAZIONALE DI GENETICA MOLECOLARE INGM - - - EUR 2 040 943 - - - HD-DittoGraph: a digital human Embryonic Stem Cell platform for Huntington's repeats - - - EUR 2 040 943 - - - Italy - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - This proposal is aimed at identifying the molecular mechanisms that have brought the human Huntington Disease-causing Huntingtin (Htt) exon 1, with its pure and unstable CAG repeat, to be shaped the way it is today. - Specifically, we intend to screen for genetic elements affecting Htt repeat length instability in dividing and postmitotic neuronal cells. The novelty of our approach relies on the construction of a human embryonic stem (hES) cell platform that - couples highly efficient CRISPR/Cas9 technology with genome-wide screenings and third generation sequencing, to test the contribution of thousands of unequivocally barcoded cis and trans modifiers on Htt exon 1 repeats instability. - - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Italy - - - HD-DittoGraph - - - ERC-2016-ADG - - - 742436 - - - - - STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS - STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS - - - EUR 2 405 625 - - - Sensitivity of human tumors to T cell attack - - - EUR 2 405 625 - - - Netherlands - Netherlands - - - Research Organisations - Research Organisations - - The goal of this project is to describe the tumor cell-intrinsic mechanisms that determine whether ‘foreign’ human cancers are sensitive or resistant to the tumor-specific T cell response they induce. In this effort, I will - focus on 3 linked questions: - - - 2022-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Netherlands - - - SENSIT - - - ERC-2016-ADG - - - 742259 - - - - - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - - - EUR 1 932 655,01 - - - Man and Nature in Developing Countries - - - EUR 1 932 655,01 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The growth required to lift a billion people out of extreme poverty will require large increases in natural resource extraction and energy consumption. The negative externalities this growth creates – through degradation of - forests and oceans, pollution and climate change – will affect us all. This is a proposal to create a new body of research on natural resource management and energy use in developing countries. It is distinctive for four reasons. First, it brings - novel, applied micro techniques from development economics to the study of environmental and energy economics. Second, it harnesses new data collection technologies using satellites and randomized control trials. Third, we pioneer the use of - political economy approaches to understand the gap between de jure and de facto policies. Finally, we innovate on policy design by embedding researchers with policy partners to co-generate research and ensure that findings scale directly into - policies. - - 2022-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - MANANDNATURE - - - ERC-2016-ADG - - - 743278 - - - - - STOCKHOLMS UNIVERSITET - STOCKHOLMS UNIVERSITET - - - EUR 1 716 970 - - - Social Media and Traditional Media in China: Political and Economic Effects - - - EUR 1 716 970 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - How is political accountability and firm performance in an autocracy affected by media? This project will analyse how economic and political outcomes in China are affected by social and traditional media. It will also use - media content to measure factors that are otherwise difficult to observe, such as political networks and the trade-off between political and economic goals in Chinese firms. An explosion of social media use in China has produced an information shock - to society and its leaders, also supplying a data shock to researchers, which is magnified by the digitization of traditional media content, and coupled with new methods for analysing this type of data, originating from the in big data and - machine-learning literatures. As a result, a large set of previously unanswerable questions are now open for research. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Sweden - - - MEDIACHINA - - - ERC-2016-ADG - - - 742983 - - - - - UNIVERSITEIT MAASTRICHT - UNIVERSITEIT MAASTRICHT - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - MUCKE HERMANN - - - EUR 149 993,71 - - - Proof of principle for a first in class neuroprotective therapy in stroke and other acute neurodegenerative conditions - - - EUR 149 993,71 - - - Netherlands - Netherlands - Germany - Austria - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Stroke represents currently one of the largest – if not the largest - unmet medical need: It is the second leading cause of death and the leading cause of disability. In contrast to this high demand for effective treatments, - there is only one drug available, a blood-clot dissolving agent. However, this drug is marginally effective has over 30 contra-indications, and bears an extremely high risk of causing fatal bleeding that 85% of all stroke patients are not treated - with it. The needed innovation would be a drug which is broadly applicable, i.e. has no contraindication, can be given in all forms of stroke and already in the ambulance, is safe, i.e. bears no risk to cause secondary bleeding, is effective, i.e. - reduces the brain infarct, increases survival and improves neurological outcomes for patients, has a different mechanism of action, i.e. is directly neuroprotective. Our therapeutic principle, discovered in the course of the ERC-ADG RadMed fulfils - all above criteria and is also commercially an innovative approach because we reduce the risk by developing only a single compound by here combining three compounds that target the same disease mechanism but at different points. We thereby expect to - dramatically reduce the likelihood risk of failure in our post-proof of concept (PoC) clinical development and commercialisation process. We here propose to conduct the final step, the PoC, before a first-in-man study in stroke. Our PoC plan has - three major objectives: To complete an IPR FTPO and Foreground analysis, to chose the optimal compounds and complete phase III pre-clinical to provide PoC for a first-in-man trial in stroke, to then allow the work-out of a complete business plan - including competitive analysis, development strategy, and commercial/business development strategy. - - 2019-09-30, Grant Agreement signed - - - 2018-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Netherlands - - - SAVEBRAIN - - - ERC-2016-PoC - - - 737586 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - ACADEMISCH ZIEKENHUIS LEIDEN - - - EUR 2 500 000 - - - Developing Geroprotectors to Prevent Polymorbidity - - - EUR 2 500 000 - - - Germany - Germany - Netherlands - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Higher or Secondary Education Establishments - - Advancing age is the major risk factor for disability and illness, including cardiovascular, metabolic and neu-rodegenerative disease and cancer. The increasing incidence of older people in European countries is posing major - medical, social and economic challenges, and there is an urgent need to find ways of compressing late-life morbidity. Ageing has proved malleable to genetic and pharmacological interventions in laboratory animals, and at least some of the mechanisms - are conserved over large evolutionary distances. Reduced activity of the nutrient-sensing insulin/insulin-like growth factor/TOR signalling network can increase health and combat ageing-related disease in laboratory animals, with increasing evidence - of its importance in human ageing. There is thus a prospect for pharmacological intervention to prevent more than one ageing-related condition, rather than tackling diseases one by one and as they arise. The aim of this research programme is to - evaluate the potential for pharmacological prevention of ageing-related decline in humans with a polypill targeting the nutrient-sensing network. We find that three licensed drugs, lithium, rapamycin and trametinib, act independently, at different - nodes in the network, to increase lifespan in the fruitfly Drosophila, implying that the network controls more than one underlying mechanism of ageing, and that a polypill of these drugs could be particularly effective. We shall test this idea in - mice, and assess the underlying mechanisms in Drosophila and mice. We have found that suppression of the Ras signalling branch of the network, which has a well known role in human cancer, can extend lifespan in both the fruitfly Drosophila and mice, - and we shall assess its role in humans. Interventions that ameliorate ageing often have sex-specific effects, and we shall investigate the mechanisms leading to these for the nutrient-sensing network. The outputs of the work will inform future - clinical trails in humans. - - 2022-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - GeroProtect - - - ERC-2016-ADG - - - 741989 - - - - - UNIVERSITAET ZU KOELN - UNIVERSITAET ZU KOELN - THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - - - EUR 1 155 104 - - - Economic Engineering of Cooperation in Modern Markets - - - EUR 1 155 104,01 - - - Germany - Germany - United States - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Cooperation is essential for the functioning of the economy and society. Thus, with inappropriate mechanisms to harness self-interest by aligning it with the common good, the outcome of social and economic interaction can be - bleak and even catastrophic. - - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - EEC - - - ERC-2016-ADG - - - 741409 - - - - - UNIVERSIDAD POMPEU FABRA - UNIVERSIDAD POMPEU FABRA - - - EUR 2 343 249 - - - Transnational Gangs as Agents of Mediation: Experiences of Conflict Resolution in Street Youth Organizations in Southern Europe, North Africa and the Americas - - - EUR 2 343 249 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - TRANSGANG aims to develop a renewed model for the analysis of transnational youth gangs in the global age, in dialogue with two classics of urban ethnography, published nearly a century ago: The Gang, by F.M. Thrasher (1926) - and The Polish Peasant in Europe and America, by W. I. Thomas and F. Znaniecki (1918-1920). To do this, the project will start by a systematic review of the historical literature on youth gangs, which will try to overcome the north-american-centrism, - dominant in contemporary criminology. The central phase of the research will focus on a multisited and multilevel ethnography that will explore experiences in which gangs have acted as agents of mediation, as well as the barriers that have blocked - these attempts. The project will compare street youth organizations from two transnational communities -Latinos and Arabs-, both in their homelands and in their new European neigbourhoods. Starting with three case studies of “good practices” in - Barcelona, Medellin and Casablanca, which will be studied in depth, contrasts with other cases in which other policies have been implemented will be established: Madrid, Marseille and Milan in southern Europe; Oran Tunis and Cairo in north Africa; - Chicago, Santiago de Cuba and San Salvador in the Americas. Using an experimental approach based on the “extended case method”, it will have as its theme the making of a film that collects the experience of members or former members of gangs who have - participated in mediation experiences. The ultimate goal is to develop a renewed transnational, inter-generational, intergeneric and transmedia approach to Twenty-First-century gangs, very different from the local, coeval, male and face-to-face model - used for understanding gangs in the Twentieth century. Although the focus of the project is theoretical, its purpose is applied: to deduce more effective ways of intervention to prevent the hegemony of the criminal gang model that appears as dominant - in the neoliberal era. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Spain - - - TRANSGANG - - - ERC-2016-ADG - - - 742705 - - - - - KOZEP-EUROPAI EGYETEM - KOZEP-EUROPAI EGYETEM - - - EUR 2 498 748 - - - Tracking and evaluating social relations and potential partners in infancy - - - EUR 2 498 748 - - - Hungary - Hungary - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In order to navigate the social world, children must understand how social interactions unfold in their society. While many recent studies have investigated how children evaluate the roles that people play in everyday - interactions and what inferences they draw from their observations, to date there is no unifying account for the conceptual repertoire and computational mechanisms used by infants to analyse their social environment. Taking a new theoretical - perspective on this topic, we plan to study whether and how human infants and young children are able to infer the social relations that underlie observed interactions. The theoretical background of this approach is based on the combination of two - proposals: (1) that actions are analysed in terms of the costs and benefits they produce to the actors and others affected, and (2) Alan Fiske’s theory, according to which human social relations could be classified into basic elementary forms. Using - a variety of behavioural and neuroimaging techniques, we intend to investigate whether children infer the specific social relation that the intentional structure and the cost-benefit outcome of an observed interaction could reveal. More specifically, - while resource transfer events (e.g., giving, taking) alter the distribution of goods among participants, they may also cue certain types of underlying relations that would ensure that all parties benefit, directly or indirectly, from the exchange on - the long run (e.g., by reciprocity). We aim to establish whether drawing inferences to social relations enjoys the priority in the infant mind over attribution of social dispositions, whether infants predict the outcome of new, previously unobserved - interactions, what information children use to choose partners for cooperative tasks, and how they track individuals across social contexts. This research will also provide a new perspective on the development of moral psychology by extending its - domain from actions to social interactions. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Hungary - - - PARTNERS - - - ERC-2016-ADG - - - 742231 - - - - - AARHUS UNIVERSITET - AARHUS UNIVERSITET - - - EUR 2 398 993 - - - Common Interactive Objects - - - EUR 2 398 993,01 - - - Denmark - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In CIO, common interactive objects are developed and explored to extend human control over the technological environment by human beings, both individually and together. CIO leads to a coherent framework of user interfaces to - be applied in interaction design. Common interactive objects will provide a useful frame for furthering human computer interaction (HCI) theory, development of interaction design methods and the underlying technical platforms. Common interactive - objects will empower users to better understand and develop the technologies they use. - - - 2022-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Denmark - - - CIO - - - ERC-2016-ADG - - - 740548 - - - - - BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION - - - EUR 170 121,60 - - - Climate monitoring and seasonal forecast for global crop production - - - EUR 170 121,60 - - - Spain - - - Research Organisations - - When provided in a climate-services context, seasonal climate forecasts can enable a more effective adaptation to climate variability and change, offering an under-exploited opportunity to minimise the agricultural impacts of - adverse climate conditions. However, the development of seasonal prediction systems of climate-driven impacts on agriculture is still largely in the early stages, especially on a global scale. CLIM4CROP is designed as a multidisciplinary project - aimed at exploring how to best exploit seasonal forecasts for crop management decision making on a global scale. This goal will be achieved through three specific supporting objectives: a) characterising the uncertainties in global datasets of - climate observations covering the last three decades and providing data in near-real time; b) understanding the role of climate as underlying mechanisms driving crop yields, and thereby developing statistical models linking climate and yields; c) - exploring the seasonal predictability of crop yields with the above-mentioned developed models and implementing a model suite operationally using the data available in near-real time. These objectives will be addressed by making use of the latest - advances in climate information, including the most complete and up-to-date sets of seasonal forecast systems. The expected outcomes of this project are an improved understanding of the interaction between climate and crop yields, and new insights - allowing more efficient crop management. This could prove useful to policy-makers and commercial entities in their decision-making processes. To this end, the transfer of knowledge to impact users is envisaged. - - 2020-11-30, Grant Agreement signed - - - 2018-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - CLIM4CROP - - - H2020-MSCA-IF-2016 - - - 740073 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 2 499 111 - - - Development of New therapies against cholangiopathies. - - - EUR 2 499 111 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Cholangiopathies represent a diverse group of diseases affecting cholangiocytes which are the main cell type of the biliary tract. These disorders range from inherited (Cystic Fibrosis) and developmental (Alagille Syndrome, - Biliary Atresia) to autoimmune (Primary Biliary Cirrhosis), idiopathic (Primary Sclerosing Cholangitis) and drug or toxin induced diseases. Cholangiopathies result in toxic bile accumulation in the liver inducing cell death and ultimately cirrhosis. - They carry high morbidity and mortality, accounting for up to a third of chronic liver disorders. Whole liver transplantation remains the main treatment. However, organ transplant requires immunosuppression with significant side effects and an - increasing number of patients die while on the transplant list due to the shortage of suitable donors. Finally, the absence of physiologically relevant in vitro systems to model and to study cholangiopathies prevents the development of new - therapeutics while cell based therapy approach have been unexplored. Here, we propose to systematically address these challenges by developing a novel and innovative program of translational research focusing on cholangiopathies. We will first - investigate the cellular and functional diversity of the biliary tract and its impact on disease by taking advantage of recent developments in single cell transcriptomic analyses. We will then use this basic knowledge to generate and to characterize - for the first time a renewable source of cholangiocytes from human induced pluripotent stem cells and from biliary tissue. The resulting cells will be used to model cholangiopathies in vitro and to create a new platform for drug target - identification. Finally, we will explore the potential for in vitro generated cholangiocytes to be used in regenerative medicine applications including cell based therapy. Overall this comprehensive program will uniquely path the way for the - development of a whole range of new therapies for cholangiopathies. - - 2022-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - New Chol - - - ERC-2016-ADG - - - 741707 - - - - - THE FRANCIS CRICK INSTITUTE LIMITED - THE FRANCIS CRICK INSTITUTE LIMITED - - - EUR 2 357 000 - - - The molecular and cellular logic of vertebrate neural development - - - EUR 2 357 000 - - - United Kingdom - United Kingdom - - - Research Organisations - Research Organisations - - A central problem in biology and key to realising the potential of regenerative medicine is understanding the mechanisms that produce and organize cells in the complex tissues of an embryo. In broad terms, initially - uncommitted progenitors acquire their fate in response to signals that control transcriptional programmes. These programmes drive cells through spatial and temporal successions of states that gradually refine cell identity. How these states are - established and cell fate decisions implemented is poorly understood. To address this we use an experimentally tractable system – the formation of defined populations of progenitors in the vertebrate spinal cord. We take an interdisciplinary approach - that combines our in vivo expertise with three recent advances in our group. First, we have developed in vitro differentiation systems and microfluidic devices that use embryonic stem cells to recapitulate development processes. Second, we have - embraced new technologies that provide unprecedented ability to manipulate and assay single cells. Finally, we have established interdisciplinary collaborations to develop computational tools and construct data driven mathematical models. Using these - approaches, alongside established embryological methods, we will establish a platform for manipulating and analysing mechanisms by which the multipotent progenitors that form the spinal cord acquire specific identities. We will identify the rules by - which cells make decisions and we will define the design logic and network architectures that lead to distinct cell fate choices. The ability to: (i) follow the trajectory of a cell as it transitions to a specific neuronal subtype in vivo; (ii) - manipulate the process in vitro and in vivo; and (iii) model it in silico, offers a unique system for understanding organogenesis. Together these approaches will provide the knowledge and technical foundations for rational, predictive tissue - engineering of the spinal cord. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - LogNeuroDev - - - ERC-2016-ADG - - - 742138 - - - - - UNIVERSITA DEGLI STUDI DI TORINO - KATHOLIEKE UNIVERSITEIT LEUVEN - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - INSTITUT CURIE - FUNDACIO PRIVADA INSTITUT D'INVESTIGACIO ONCOLOGICA DE VALL-HEBRON - STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS - Masarykova univerzita - EUROPEAN MOLECULAR BIOLOGY LABORATORY - BIOBANKS AND BIOMOLECULAR RESOURCES RESEARCH INFRASTRUCTURE CONSORTIUM (BBMRI-ERIC) - ROYAL COLLEGE OF SURGEONS IN IRELAND - INSTITUT CATALA D'ONCOLOGIA - THE UNIVERSITY OF MANCHESTER - ACADEMISCH ZIEKENHUIS GRONINGEN - OSLO UNIVERSITETSSYKEHUS HF - ISTITUTO EUROPEO DI ONCOLOGIA SRL - HOSPITAL UNIVERSITARIO DE FUENLABRADA - KAIROS3D SRL - OCELLO BV - SEEDING SCIENCE - - - EUR 5 156 198,75 - - - EurOPDX Distributed Infrastructure for Research on patient-derived cancer Xenografts - - - EUR 5 156 198,75 - - - Italy - Belgium - United Kingdom - France - Spain - Netherlands - Czech Republic - Germany - Austria - Ireland - Spain - United Kingdom - Netherlands - Norway - Italy - Spain - Italy - Netherlands - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Counteracting high attrition rates in oncology drug development and providing optimal therapeutic management of cancer patients require preclinical models that properly recapitulate the complexity and diversity of human - tumours. Patient-derived tumour xenografts (PDXs), established by transplanting tumour fragments into immunodeficient mice, are being widely embraced by the scientific community as preclinical tools for target and biomarker discovery. The overall - goal of EDIReX is to establish a cutting-edge European infrastructure offering Trans-national Access (TA) of PDX resources to academic and industrial cancer researchers, including the distribution of cryopreserved samples to third parties, the - structured biobanking of user-developed models, and the performance of efficacy studies. To ensure interoperability in services, TA initiatives will be backed by Networking Activities (NAs); these will be mainly centred around the establishment of - standard procedures for PDX quality control, long-term storage and therapeutic mouse trials. NAs will also entail the adoption of shared ethics parameters for animal experimentation, the wide dissemination of services and project results, and the - design of plans to ensure sustainability of the infrastructure. User outreach will be maximised by Joint Research Activities through a three-pronged approach: i) the implementation of a public Data Portal for efficient and user-friendly query and - visualisation of clinical, molecular and pharmacological annotation of the models; ii) a cross-validation mouse trial to harmonise inter-laboratory procedures, thus improving the quality and reliability of service provision; and iii) the development - of exploratory, more advanced PDX-based preclinical platforms, such as orthotopic and humanised models and in vitro PDX-derived cells. Capitalising on all these assets, EDIReX will contribute to structuring the European Research Area and global - cooperation of research infrastructures. - - 2022-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.2."> - - - INFRAIA-02-2017 - Integrating Activities for Starting Communities - - - RIA - Research and Innovation action - - - Italy - - - EDIReX - - - H2020-INFRAIA-2017-1-two-stage - - - 731105 - - - - - ALFRED-WEGENER-INSTITUT HELMHOLTZ-ZENTRUM FUR POLAR- UND MEERESFORSCHUNG - POLARFORSKNINGSSEKRETARIETET - NORSK POLARINSTITUTT - UNIVERSITE LAVAL - University of Alaska - NORDURSLODAGATTIN EHF - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - CONSIGLIO NAZIONALE DELLE RICERCHE - WOC - WORLD OCEAN LIMITED - INSTYTUT OCEANOLOGII POLSKIEJ AKADEMII NAUK - ILMATIETEEN LAITOS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - NATURAL ENVIRONMENT RESEARCH COUNCIL - DANMARKS TEKNISKE UNIVERSITET - - - EUR 5 996 563,75 - - - Arctic Research Icebreaker Consortium: A strategy for meeting the needs for marine-based research in the Arctic - - - EUR 5 996 567,50 - - - Germany - Sweden - Norway - Canada - United States - Iceland - Spain - Italy - United Kingdom - Poland - Finland - France - United Kingdom - Denmark - - - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Other - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - - The recent changes of the Arctic and the increased economic activity in the region have triggered a demand for accurate sea-ice and weather predictions, for information on the status of the Arctic Ocean, and for complex - predictions of future scenarios. To address these issues of particular environmental and societal concern and to develop policy recommendations for a sustainable usage of the Arctic Ocean and its resources, the Arctic science community needs - world-class research icebreakers (RIs) to access the ice-covered Arctic Ocean. The current shortage of availability of RIs and a not optimally coordinated polar research fleet impedes Europe’s capacity to investigate this region. There is thus an - urgent need for providing European researchers with better RI capacities for the Arctic. ARICE aims at reaching this goal with the existing polar fleet by: - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.2."> - - - INFRAIA-02-2017 - Integrating Activities for Starting Communities - - - RIA - Research and Innovation action - - - Germany - - - ARICE - - - H2020-INFRAIA-2017-1-two-stage - - - 730965 - - - - - UNIVERSIDADE DO PORTO - UNIVERSITAET BREMEN - ASSOCIACAO DO INSTITUTO SUPERIOR TECNICO PARA A INVESTIGACAO E DESENVOLVIMENTO - UNIVERSITA DEGLI STUDI DI GENOVA - SVEUCILISTE U ZAGREBU FAKULTET ELEKTROTEHNIKE I RACUNARSTVA - UNIVERSITAT DE GIRONA - UNIVERSITY OF LIMERICK - CONSORCIO PARA EL DISENO, CONSTRUCCION, EQUIPAMIENTO Y EXPLOTACION DE LA PLATAFORMA OCEANICA DE CANARIAS - NATO SCIENCE AND TECHNOLOGY ORGANISATION - HERIOT-WATT UNIVERSITY - NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU - MARINE INSTITUTE - DISTRETTO LIGURE DELLE TECNOLOGIE MARINE SCRL - NATURAL ENVIRONMENT RESEARCH COUNCIL - INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER - - - EUR 4 998 736,75 - - - Marine robotics research infrastructure network - - - EUR 4 998 736,75 - - - Portugal - Germany - Portugal - Italy - Croatia - Spain - Ireland - Spain - Belgium - United Kingdom - Norway - Ireland - Italy - United Kingdom - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Research Organisations - - Our oceans are the least-explored region of planet Earth. Protection and sustainable development of ocean resources presents formidable challenges. Robots will play an increasingly key role in the near future and this role - will expand and become more challenging as we extend into deeper, remote and hostile marine environments. Europe leads in many aspects of maritime, but lacks well integrated and coordinated oceanic robotic infrastructure or presence. - - 2021-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.2."> - - - INFRAIA-02-2017 - Integrating Activities for Starting Communities - - - RIA - Research and Innovation action - - - Portugal - - - EUMarineRobots - - - H2020-INFRAIA-2017-1-two-stage - - - 731103 - - - - - SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO SANT'ANNA - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - KARLSRUHER INSTITUT FUER TECHNOLOGIE - TECHNISCHE UNIVERSITAET MUENCHEN - FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA - UNIVERSITEIT TWENTE - UNIVERSITAT POLITECNICA DE CATALUNYA - UNIVERSIDAD DE SEVILLA - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - UNIVERSITY OF THE WEST OF ENGLAND, BRISTOL - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - UNIVERZA V LJUBLJANI - - - EUR 4 999 236,25 - - - The European Robotics Research Infrastructure Network - - - EUR 4 999 236,25 - - - Italy - France - France - Germany - Germany - Italy - Netherlands - Spain - Spain - Switzerland - United Kingdom - United Kingdom - Slovenia - - - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Chiara Andreoli - Tel.: +3901071781854 - Fax: +39 010 7170817 - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - After a few decades of intense research and development, Robotics has produced radical innovation and impact in many sectors (manufacturing, space, medicine…). In addition Robotics has generated novel scientific and - engineering knowledge. This is due to the unique nature of Robotics, that has evolved from a predominantly engineering-oriented domain, to a transdisciplinary area including and inspiring many different disciplines. Europe is an undisputed leader in - Robotics: it has nurtured a large community of researchers, educated many thousand students, created large and small companies, and established advanced facilities for conducting scientific research and contributing to technological innovation. - However, despite of significant efforts and achievements, the existing Robotics facilities are not fully synchronized, and lack common procedures, thus hampering their enormous potential for world class research and innovation. Creating a Robotics - Research Infrastructure is realistic, timely and essential in the current and future landscape of Robotics. The European Robotics Research Infrastructures Network (TERRINet) project aims at building a world-class network with harmonised services and - complementary capabilities where talented researchers from academia and industry worldwide will have access and will be able to explore new ideas and establish personal and joint projects; to get in contact with and be inspired by leading and - creative scientists, technologists, experts and industrial representatives; to share information and gain knowledge for boosting their scientific research and potential for technological innovation. The plan of TERRINet is to accomplish its vision by - providing not only an organised and well orchestrated set of facilities, but also databases, tools and methodologies which will remain operational after the end of the project, so to provide a long-term service to Robotics science and industry in - Europe and worldwide. - - 2021-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.2."> - - - INFRAIA-02-2017 - Integrating Activities for Starting Communities - - - RIA - Research and Innovation action - - - Italy - - - TERRINet - - - H2020-INFRAIA-2017-1-two-stage - - - 730994 - - - - - INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE - INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE TOULOUSE INSAT - VLAAMSE INSTELLING VOOR TECHNOLOGISCH ONDERZOEK N.V. - UNIVERSITE DE NANTES - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - Teknologian tutkimuskeskus VTT Oy - UNIVERSITAT AUTONOMA DE BARCELONA - CONSIGLIO NAZIONALE DELLE RICERCHE - NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - THE UNIVERSITY OF MANCHESTER - KNIME.GMBH - WAGENINGEN UNIVERSITY - LIFEGLIMMER GMBH - INRA TRANSFERT S.A. - - - EUR 5 000 000 - - - Industrial Biotechnology Innovation and Synthetic Biology Accelerator - - - EUR 5 000 157,97 - - - France - France - Belgium - France - Germany - Finland - Spain - Italy - Greece - France - Spain - United Kingdom - Germany - Netherlands - Germany - France - - - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The overarching aim of IBISBA 1.0 is to support and accelerate the uptake of industrial biotechnology as a key enabling technology for advanced manufacturing. To do this, IBISBA 1.0 will provide a distributed network of - research infrastructure facilities to promote R&D in bioprocess development and support this bioeconomy KET. The facilities cover a variety of experimental and in silico operations and disciplines, and together represent the R&D continuum in - the range TRL2 to 6 needed to build quality biomanufacturing processes for industrialization. In addition to hardware, IBISBA 1.0 will operate an ICT platform, linking all project events occurring on facilities, and external data repositories, and - provide users with end-to-end project management and access to a wide variety of research assets. Together, these developments create the basis for a future pan-European research infrastructure for industrial biotechnology, the feasibility of which - will be established during the project. Through IBISBA 1.0, the participant facilities will be opened for transnational access, thus providing cutting edge technologies to a cross section of Europe’s researchers, including early career stage - scientists. Users and facility operators will receive remote and on-site training, and immersion in the hallmark multidisciplinary environment of IBISBA 1.0. Transnational access will be facilitated by an ambition outreach plan that will provide - users, including SMEs and other industry players, with complete information about service offers, but also insight into the potentiality of IPR held by IBISBA 1.0 partners and the opportunities for innovation. Interoperability will be a focus of - considerable attention, with actions directed towards harmonization and the implementation of repeatable working practices that integrate experimentation with data analysis, and data management, thus providing the basis for the sharing and reuse of - data assets in a framework of Open Science. - - 2021-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.2."> - - - INFRAIA-02-2017 - Integrating Activities for Starting Communities - - - RIA - Research and Innovation action - - - France - - - IBISBA 1.0 - - - H2020-INFRAIA-2017-1-two-stage - - - 730976 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 195 454,80 - - - Deciphering Regulatory DNA and Transcription Factor Binding Sites in C3 and C4 Species with Varying Water Use Efficiencies - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Water-related stress is the number one limiting factor for plant productivity and human well-being. One-third of the current world population faces water shortages and by 2025, two-thirds are expected to experience water - stress conditions, i.e 1.8 billion people will be subjected to absolute water scarcity. - - 2020-06-30, Grant Agreement signed - - - 2018-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - Trans C4 - - - H2020-MSCA-IF-2016 - - - 735105 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSITE DE LIEGE - MIKROBIOLOGICKY USTAV - AVCR, V.V.I. - UNIVERSITAET ROSTOCK - ITA-SUOMEN YLIOPISTO - UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA - FCIENCIAS.ID - ASSOCIACAO PARA A INVESTIGACAO E DESENVOLVIMENTO DE CIENCIAS - SKOLKOVO INSTITUTE OF SCIENCE AND TECHNOLOGY - THE UNIVERSITY OF WARWICK - BRUKER DALTONIK GMBH - CASC4DE - ABSISKEY - - - EUR 4 988 746,50 - - - European Network of Fourier-Transform Ion-Cyclotron-Resonance Mass Spectrometry Centers - - - EUR 5 032 451,97 - - - France - Belgium - Czech Republic - Germany - Finland - Italy - Portugal - Russia - United Kingdom - Germany - France - France - - - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Other - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - EU_FT-ICR_MS proposal aims to establish a European network of FT-ICR (Fourier Transform Ion Cyclotron Resonance) mass spectrometry (MS) centers in association with a manufacturer and a SME software company. Mass spectrometry - (MS) has become the most ubiquitous analytical techniques in use today, providing more information on the composition and the structure of a substance from a smaller amount of sample than any other techniques. Unlike other analytical techniques, such - as NMR, which mainly rely on a unique technology, MS is characterized by the existence of a large range of mass analyzers. FT-ICR MS is the most powerful MS technique. It offers up to 100 fold higher mass resolving power and mass accuracy than any - other MS technique. On the contrary to NMR community with which the FT-ICR MS shares several features, FT-ICR MS has never been involved in a European INFRA network and so will be a legitimate candidate to the Integrating Activities for Starting - Communities call. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.2."> - - - INFRAIA-02-2017 - Integrating Activities for Starting Communities - - - RIA - Research and Innovation action - - - France - - - EU_FT-ICR_MS - - - H2020-INFRAIA-2017-1-two-stage - - - 731077 - - - - - INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE - SRUC - WAGENINGEN UNIVERSITY - STICHTING WAGENINGEN RESEARCH - THE UNIVERSITY OF READING - LEIBNIZ-INSTITUT FUR NUTZTIERBIOLOGIE - TEAGASC - AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY - AARHUS UNIVERSITET - INSTITUT DE RECERCA I TECNOLOGIA AGROALIMENTARIES - CENTRE WALLON DE RECHERCHES AGRONOMIQUES - INSTITUT DE L'ELEVAGE - FEDERAZIONE EUROPEA DI ZOOTECNICA - AGRIMETRICS LIMITED - INRA TRANSFERT S.A. - - - EUR 4 999 943,75 - - - SmartCow: an integrated infrastructure for increased research capability and innovation in the European cattle sector - - - EUR 4 999 943,75 - - - France - United Kingdom - Netherlands - Netherlands - United Kingdom - Germany - Ireland - Denmark - Spain - Belgium - France - Italy - United Kingdom - France - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Other - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - SmartCow integrates key European cattle research infrastructures, to promote their coordinated use and development and thereby help the European cattle sector face the challenge of sustainable production. Covering all the - relevant scientific fields and the diversity of cattle types and production systems, SmartCow will provide the academic and private research communities with easy access to 11 major research infrastructures from 7 countries (18 installations) of high - quality services and resources. These are needed to develop innovative and ethical solutions for efficient use of animal and feed resources that promote animal welfare and healthy livestock, as well as sustainable competitiveness. - - 2022-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.2."> - - - INFRAIA-02-2017 - Integrating Activities for Starting Communities - - - RIA - Research and Innovation action - - - France - - - SmartCow - - - H2020-INFRAIA-2017-1-two-stage - - - 730924 - - - - - THE UNIVERSITY OF BIRMINGHAM - DOUGLAS CONNECT GMBH - NATURAL ENVIRONMENT RESEARCH COUNCIL - NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA - UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN - ACONDICIONAMIENTO TARRASENSE ASSOCIACION - BUNDESINSTITUT FUER RISIKOBEWERTUNG - BIONANONET FORSCHUNGSGESELLSCHAFT MBH - PARIS-LODRON-UNIVERSITAT SALZBURG - NOVAMECHANICS LIMITED - BIOMAX INFORMATICS AG - UNIVERSITEIT MAASTRICHT - DUKE UNIVERSITY - - - EUR 5 400 000 - - - The European Nanotechnology Community Informatics Platform: Bridging data and disciplinary gaps for industry and regulators (NanoCommons) - - - EUR 5 586 000,46 - - - United Kingdom - Switzerland - United Kingdom - Greece - Ireland - Spain - Germany - Austria - Austria - Cyprus - Germany - Netherlands - United States - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Nanotechnologies and the resulting novel and emerging materials (NEMs) represent major areas of investment and growth for the European economy. Recent advances have enabled confidence in the understanding of what constitutes - toxicity of NEMs in relation to health and environmental hazards. However, the nanotechnology and nanosafety communities remain disparate and unconnected, whilst knowledge and data remain fragmented and inaccessible, such that from a data integrating - and mining perspective it is clearly a “starting community”. The field, and indeed the European open knowledge economy, requires conversion of these scientific discoveries into legislative frameworks and industrial applications, which can only be - achieved through concerted efforts to integrate, consolidate, annotate and facilitate access to the disparate datasets. NanoCommons brings together academia, industry and regulators to facilitate pooling and harmonising of methods and data for - modelling, safe-by-design product development and regulatory approval purposes, thereby driving best practice and ensuring maximum access to data and tools. Networking Activities span community needs assessment through development of demonstration - case studies (e.g. exemplar regulatory dossiers). Joint Research Activities will integrate existing resources and organise efficient curation, preservation and facilitate access to data/models. Transnational Access will focus on standardisation of - data generation workflows across the disparate communities and establishment of a common access procedure for transnational and/or virtual access to the data, and modelling and risk prediction/management tools developed and integrated. Given the - extremely rapid pace of development of nanoinformatics, NanoCommons’s detailed workplan will be prescribed for the first 18 months, beyond which it will be co-developed with stakeholders on a rolling call basis to ensure maximum responsiveness to - community needs. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.2."> - - - INFRAIA-02-2017 - Integrating Activities for Starting Communities - - - RIA - Research and Innovation action - - - United Kingdom - - - NanoCommons - - - H2020-INFRAIA-2017-1-two-stage - - - 731032 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - - - EUR 187 866 - - - The unseen adaptation of a non-native: A unique spatiotemporal study of infection dynamics and immunogenetics at a bioinvasion front - - - EUR 187 866 - - - Ireland - - - Higher or Secondary Education Establishments - - Emerging infectious diseases (EIDs) are an increasing threat to global health and there is an urgent need to understand the processes involved in their spread. The majority of EIDs originate from wildlife, for example the - recent outbreaks of ebola, zika virus and lassa fever. One of the primary drivers of EIDs is human intervention via host or parasite translocations. A unique opportunity to study the processes involved in EIDs, currently exists in Ireland due to the - introduction of the bank vole (Myodes glareolus), via Germany in the 1920’s. The continuing range expansion of the bank vole within Ireland presents a natural large-scale perturbation experiment, with empirical data and known expansion routes already - available. This knowledge, which is based in part on data I am currently collecting, combined with bank voles being an established model species for studying disease dynamics, creates an ideal and rare system to study the factors that influence the - invasion process and the emergence of infectious diseases. The primary objective of the proposal is to conduct a spatiotemporal study analysing the infection dynamics of native and invasive species in relation to immune phenotype. A temporal study - will allow the process of adaptation, as the invasive species becomes established, to be observed for the first time. I will be mentored by and collaborate with world leaders in disease ecology in Ireland and other European countries to accomplish my - goals. The Marie Skłodowska-Curie fellowship would enable me to build on my disease ecology research experience and to develop a unique bio-invasion model system in Europe. It will enable me to develop expertise in the emerging field of - ecoimmunology, establishing my position as a key scientist in this innovative field of research. - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Ireland - - - INVASIMMUN - - - H2020-MSCA-IF-2016 - - - 749312 - - - - - Institute of Science and Technology Austria - Institute of Science and Technology Austria - - - EUR 1 996 030 - - - Principles of Neural Stem Cell Lineage Progression in Cerebral Cortex Development - - - EUR 1 996 030 - - - Austria - Austria - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The cerebral cortex consists of an extraordinary number and great diversity of neurons. Yet, how the cortical entity, with all its functional neuronal circuits, arises from the neural stem cells (NSCs) in the developing - neuroepithelium is a major unsolved question in Neuroscience. Radial glia progenitors (RGPs) are responsible for producing nearly all neocortical neurons and a certain fraction of cortical glia including astrocytes. Our recent efforts provide - evidence for a high degree of non-stochasticity and thus deterministic nature of RGP behavior in the mammalian neocortex. However, the cellular and molecular mechanisms controlling RGP lineage progression through proliferation, neurogenesis and - especially gliogenesis are unknown. In a pursuit to obtain definitive insights into these fundamental questions we assess RGP lineage progression at the unprecedented single cell resolution, using the unique genetic MADM (Mosaic Analysis with Double - Markers) technology. MADM offers an unparalleled approach to visualize and concomitantly manipulate sparse clones and small subsets of genetically defined neurons. Within the scope of this project we will use multidisciplinary experimental approaches - to establish a research program with the following major objectives: We will 1) Functionally dissect the relative contribution of cell-autonomous intrinsic signaling and cell-non-autonomous effects in RGP lineage progression; 2) Define the principles - of lineage progression in human RGPs in situ using MADM technology in cerebral organoid system; 3) Decipher the logic of glia lineage progression in the neocortex. The ultimate goal of the proposed research is to establish a definitive quantitative - framework and mechanistic model of lineage progression in cortical NSCs. As such, the proposed research shall precipitate into extensive conceptual progress regarding the fundamental cellular and molecular principles of cerebral cortex development. - - 2022-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Austria - - - LinPro - - - ERC-2016-COG - - - 725780 - - - - - INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM - INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM - - - EUR 149 379 - - - Microfluidic bubble JET flow CELL sorter for cell therapy - - - EUR 149 379 - - - Belgium - Belgium - - - Research Organisations - Research Organisations - - 'T cell based cancer therapy has been recognized as one of the most promising future cancer therapy methods. In a typical T cell therapy course, relevant T cells are isolated from the patient’s blood, modified against certain - cancer markers, and infused back into the patient’s body where the engineered T cells direct the immune system to attack and finally eliminate the malignant tumor cells and tissues. - - - 2019-06-30, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Belgium - - - JetCell - - - ERC-2016-PoC - - - 727730 - - - - - WAGENINGEN UNIVERSITY - WAGENINGEN UNIVERSITY - - - EUR 1 999 843 - - - Surviving salinity: How do plants sense Na+? - - - EUR 1 999 843 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - A major gap in our knowledge of how plants respond to soil salinity is their initial perception of sodium (Na+) ions. Salt is detrimental to plants and soil salinization is an increasing threat to global food security; 6% of - the world’s total land area and 20% of irrigated land is affected by salinity. I recently discovered Na+-specific root growth responses of plants and will now exploit these to identify the elusive sodium sensing mechanism of plants. I will use an - innovative approach combining genome-wide genetic screens in the model plant Arabidopsis thaliana with dedicated biochemical assays. - - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - Sense2SurviveSalt - - - ERC-2016-COG - - - 724321 - - - - - UNIVERSITA DEGLI STUDI DI PAVIA - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - INSTITUT GUSTAVE ROUSSY - INTEGRATED SYSTEMS ENGINEERING SRL - CELLINK AB - KNOWLEDGE INNOVATION MARKET S.L. - - - EUR 2 998 500 - - - Genetically engineered human pluripotent stem cells, functionalized silk-fibroin platforms and bio-inks: a novel solution for large-scale ex-vivo platelet production, transfusion and drug research - - - EUR 2 998 500,01 - - - Italy - United Kingdom - France - Italy - Sweden - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The demand for human platelets (plts) for medical research and clinical applications is massive. The primary goal of SilkFUSION is to engineer groundbreaking 3D nanotechnologies for large-scale production of blood plts for - human transfusion from human pluripotent stem cells (hPSCs). Our hypothesis is that plt production ex-vivo can be optimized by providing megakaryocytes (Mks) with the correct physical and biochemical environment. - - 2021-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-01-2016-2017 - FET-Open research and innovation actions - - - RIA - Research and Innovation action - - - Italy - - - SilkFUSION - - - H2020-FETOPEN-1-2016-2017 - - - 767309 - - - - - UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - STICHTING IMEC NEDERLAND - KARLSRUHER INSTITUT FUER TECHNOLOGIE - POLITECNICO DI TORINO - ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA - UNIVERSITA DEGLI STUDI DI PERUGIA - UNIVERSITY OF SOUTHAMPTON - - - EUR 5 213 481,25 - - - European Infrastructure Powering the Internet of Things - - - EUR 5 214 731,25 - - - Ireland - France - Germany - Netherlands - Germany - Italy - Italy - Italy - United Kingdom - - - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - EnABLES will integrate key European research infrastructures in powering the Internet of Things (IoT). 6 research institutes together with 5 knowledge hubs of excellence will address the long term needs of energy management in - self-powered smart sensor systems as required by IoT innovation. To enable truly ‘invisible’, unobtrusive and self-powered (autonomous) wireless devices a key challenge is to bridge the gap between capturing energy supply from energy harvesting - sources (EH), integrating new devices for energy storage (ES) and taking into account the micro-power management (MPM) requirements for the miniaturised system operation. Through providing access to unique infrastructure, world-leading expertise, - advanced equipment and state-of-the-art technologies, EnABLES will empower several hundreds of academic researchers and technologists to advance energy harvesting, storage and micropower management solutions for the integrated design and deployment - of miniaturised autonomous sensors. Access will range from materials & models to devices and systems and the access providers will work with the user community to accelerate adoption and innovation in real-life applications. The EnABLES - integration offers a paradigm shift in building an infrastructure network that links new scientific knowledge with application-driven research. Specifically for energy management solutions, this will deliver a mind-set change for early concurrent and - collaborative development of system-optimised IoT devices. This presents a unique opportunity for Europe to uphold global leadership in microsystem energy management and be positioned at a pivotal time at the heart of the IoT innovation. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.2."> - - - INFRAIA-02-2017 - Integrating Activities for Starting Communities - - - RIA - Research and Innovation action - - - Ireland - - - EnABLES - - - H2020-INFRAIA-2017-1-two-stage - - - 730957 - - - - - CONSIGLIO NAZIONALE DELLE RICERCHE - UNIVERSITA CA' FOSCARI VENEZIA - UNIVERSITY OF PIRAEUS RESEARCH CENTER - UNIVERSITE DE VERSAILLES SAINT-QUENTIN-EN-YVELINES. - HAROKOPIO UNIVERSITY - DIMOS THIRAS - UNIVERSIDADE FEDERAL DE SANTA CATARINA. - UNIVERSIDADE FEDERAL DO CEARA - FACULDADES CATOLICAS ASSOCIACAO SEM FINS LUCRATIVOS - DALHOUSIE UNIVERSITY - - - EUR 504 000 - - - Multiple ASpects TrajEctoRy management and analysis - - - EUR 576 000 - - - Italy - Italy - Greece - France - Greece - Greece - Brazil - Brazil - Brazil - Canada - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - An ever-increasing number of diverse, real-life applications, ranging from mobile phone calls to social media and land, sea, and air surveillance systems, produce massive amounts of spatio-temporal data representing - trajectories of moving objects. Trajectories, commonly represented by sequences of timestamps and position coordinates, thanks to the high availability of contextual and semantic-rich data can be enriched and are evolving to more comprehensive and - semantically significant objects. In the MASTER project we envision holistic trajectories, meaning trajectories characterized by the fact that the spatio-temporal and semantic aspects are intimately correlated and should be considered as a whole. - However current state of art does not provide management and analysis methods “ready for use” for these multiple aspects trajectories. - - - 2022-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Italy - - - MASTER - - - H2020-MSCA-RISE-2017 - - - 777695 - - - - - BIOSENSE INSTITUTE - RESEARCH AND DEVELOPMENT INSTITUTE FOR INFORMATION TECHNOLOGIES IN BIOSYSTEMS - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - THE UNIVERSITY OF BIRMINGHAM - INOSENS DOO NOVI SAD - PLASMORE SRL - THE UNIVERSITY OF TEXAS SYSTEM - THE AUSTRALIAN NATIONAL UNIVERSITY - RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK - - - EUR 553 500 - - - Non-Conventional Wave Propagation for Future Sensing and Actuating Technologies - - - EUR 580 500 - - - Serbia - Switzerland - United Kingdom - Serbia - Italy - United States - Australia - United States - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - - New sensing devices and technologies are the key in addressing numerous challenges that agriculture is facing today. Namely, to provide more food for the ever-growing population, a number of biophysical parameters of plants, - soil and food products need to be monitored and measured constantly, thus providing valuable data needed to optimize the entire agricultural process. In addition, the corresponding actuating technologies responsible for applying various measures - (e.g. irrigation, fertilization) need to become more precise and allow variable rate inputs with a resolution down to an individual plant. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Serbia - - - NOCTURNO - - - H2020-MSCA-RISE-2017 - - - 777714 - - - - - Eidgenössische Technische Hochschule Zürich - Eidgenössische Technische Hochschule Zürich - - - EUR 150 000 - - - Carrier for Cure: tailored combination drug delivery solutions for oncology - - - EUR 150 000 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Chemotherapy, often given in conjunction with other therapies is infamous for its off target associated side effects. Recent studies have shown that drugs combinations can act synergistically at certain ratios and are more - effective and less toxic than single drug therapies. Despite promising in vitro results, combination drug therapy for Oncology has not been successfully translated to the clinic due to lack of efficient delivery systems that can maintain the desired - synergistic drug concentrations in the body as each drug has a different pharmacokinetics and toxicity profile. The objective of this project is to develop a universal platform for simultaneous delivery of multiple drugs to specific cells in vivo - using a protein cage that was developed in our laboratory for encapsulation of diverse cargoes. - - 2019-04-30, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Switzerland - - - CfC - - - ERC-2017-PoC - - - 768667 - - - - - TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY - TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY - - - EUR 1 500 000 - - - Neuronal regulation of immunity - - - EUR 1 500 000 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The philosophical ‘mind-body problem’ examines the relationship between the mind, a mental process, and its impact on the body, a physical entity. It has multiple manifestations in modern medicine, for example, the emergence - of disease following stress, or recovery in response to placebo treatment. Nevertheless, this fundamental aspect of physiology remains largely unexplored. Here we propose to approach this question by focusing on a specific aspect of brain-body - interactions. Namely, to study how the brain's interoceptive site, the insular cortex, affects the immune system, the body’s main protective mechanism. We will explore the interactions between the insula and the immune system on two levels. First, we - will focus on the insula and its projections within the brain; secondly, we will study the role of projections from the brain, specifically, the peripheral nervous system (PNS), which innervates all the immunological organs. We will use chemogenetics - to activate/inhibit the activity of neurons in the insula, and optogenetics to locally control, using light, the activity of sympathetic and parasympathetic neurons innervating immunological sites. We will then characterize the effects of these - neuronal manipulations on the immune system to decipher fundamental principles of the dialog between nerve and immune cells with the long term goal of harnessing the brain’s therapeutic potential. My multidisciplinary background places me in a unique - position to investigate brain regulation of immunity, and our preliminary data support our central hypothesis that the brain and, specifically, the insula, regulate immune responses. Taken together, this study promises to alter our understanding of - brain-body interactions, and to set the stage for novel approaches to analyze how the state of the mind impacts physiology. - - 2022-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Israel - - - NEIMO - - - ERC-2017-STG - - - 758952 - - - - - THE UNIVERSITY OF NOTTINGHAM - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - KUNGLIGA TEKNISKA HOEGSKOLAN - OFFICE NATIONAL D'ETUDES ET DE RECHERCHES AEROSPATIALES - R.TECH - Zhejiang University - BEIHANG UNIVERSITY - XI'AN JIAOTONG UNIVERSITY - JOHNS HOPKINS UNIVERSITY - - - EUR 504 000 - - - Control of turbulent friction force - - - EUR 706 500 - - - United Kingdom - United Kingdom - Sweden - France - France - China - China - China - United States - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - CTFF is a major interdisciplinary project that combines wisdoms in three academic disciplines: Heat Transfer, Fluid Physics and Plasma Physics, to address the research problem on both active and passive control of turbulent - friction force. The main focus is on developing techniques for the control of near-wall turbulent structures and the reduction of turbulent friction force, specifically at conditions relevant to engineering practices, by coordinating the efforts of - European, the US and Chinese experts specialized in these three different but overlapping domains. New materials will be examined, novel numerical algorithms will be developed, and the numerical results will be tested in physical experiments. In - brief, the main objective of this project is to coordinate the action of a group of Universities and enterprises, with complementary expertise in three disciplines from European countries, China and the US, to build and test an optimal solution for - the reduction of turbulent friction drag, thereby facilitating the successful implementation of friction force control in engineering practices. - - 2020-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - United Kingdom - - - CTFF - - - H2020-MSCA-RISE-2017 - - - 777717 - - - - - CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL - CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL - - - EUR 150 000 - - - Microchannels for controlling cellular mechanotransduction - - - EUR 150 000 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Cells respond to external mechanical stimuli through an activation of a cellular mechanism called mechanotransduction. The cellular responses in this mechanism are expressed by a modification in cellular proliferation, - migration and differentiation, as well as in a strengthening of their adhesion. Likewise, diseases such as cancer and cardiac dysfunctions are also related to cellular mechanotransduction. Here we propose to take a novel 3D material porous material - towards commercial applications. The material serves as a platform for controlling mechanotransduction (e.g. in implant materials) and enables a control of mechanotransduction by mimicking natural 3D cellular environments. Our material contains a - novel form of microporous structures represented by micron-sized channels embedded in a polymer matrix of a well-defined stiffness that has been developed within the ERC project CELLINSPIRED. The material guarantees pore interconnectivity - independently of pore density and size, a unique feature offered by our fabrication procedure, for which we have applied for a patent (EP 15166793.8, PCT/EP2016/060160). Furthermore, it also provides a large, three-dimensionally controlled - cell-surface contact area, such that the mechanical properties of the environment will have large impact on the cells. Our goal in this project is to validate our novel material for cellular applications where mechanotransduction is targeted. The - expected outcome of our project is to receive a demonstrator material that (1) has well-defined mechanical properties, porosities and pore dimensions, (2) is biocompatible and can be sterilized, (3) can be fabricated in different levels of - complexity, (4) can activate mechanotransduction in cells, and (5) can be fabricated using high-throughput processes. As for commercialization, we aim to license the patent to biomaterials companies involved in applications that range from 3D cell - cultures to implant materials. - - 2019-03-31, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Germany - - - CHANNELMAT - - - ERC-2017-PoC - - - 768740 - - - - - FUNDACAO D. ANNA SOMMER CHAMPALIMAUD E DR. CARLOS MONTEZ CHAMPALIMAUD - FUNDACAO D. ANNA SOMMER CHAMPALIMAUD E DR. CARLOS MONTEZ CHAMPALIMAUD - - - EUR 1 500 000 - - - Circuit mechanisms of self-movement estimation during walking - - - EUR 1 500 000 - - - Portugal - Portugal - - - Research Organisations - Research Organisations - - The brain evolves, develops, and operates in the context of animal movements. As a consequence, fundamental brain functions such as spatial perception and motor control critically depend on the precise knowledge of the ongoing - body motion. An accurate internal estimate of self-movement is thought to emerge from sensorimotor integration; nonetheless, which circuits perform this internal estimation, and exactly how motor-sensory coordination is implemented within these - circuits are basic questions that remain to be poorly understood. There is growing evidence suggesting that, during locomotion, motor-related and visual signals interact at early stages of visual processing. In mammals, however, it is not clear what - the function of this interaction is. Recently, we have shown that a population of Drosophila optic-flow processing neurons —neurons that are sensitive to self-generated visual flow, receives convergent visual and walking-related signals to form a - faithful representation of the fly’s walking movements. Leveraging from these results, and combining quantitative analysis of behavior with physiology, optogenetics, and modelling, we propose to investigate circuit mechanisms of self-movement - estimation during walking. We will:1) use cell specific manipulations to identify what cells are necessary to generate the motor-related activity in the population of visual neurons, 2) record from the identified neurons and correlate their activity - with specific locomotor parameters, and 3) perturb the activity of different cell-types within the identified circuits to test their role in the dynamics of the visual neurons, and on the fly’s walking behavior. These experiments will establish - unprecedented causal relationships among neural activity, the formation of an internal representation, and locomotor control. The identified sensorimotor principles will establish a framework that can be tested in other scenarios or animal systems - with implications both in health and disease. - - 2022-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Portugal - - - activeFly - - - ERC-2017-STG - - - 759782 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 242 400 - - - Elliptic Combinatorics: Solving famous models from combinatorics, probability and statistical mechanics, via a transversal approach of special functions - - - EUR 1 242 400 - - - France - France - - - Research Organisations - Research Organisations - - I am willing to solve several well-known models from combinatorics, probability theory and statistical mechanics: the Ising model on isoradial graphs, dimer models, spanning forests, random walks in cones, occupation time - problems. Although completely unrelated a priori, these models have the common feature of being presumed “exactly solvable” models, for which surprising and spectacular formulas should exist for quantities of interest. This is captured by the title - “Elliptic Combinatorics”, the wording elliptic referring to the use of special functions, in a broad sense: algebraic/differentially finite (or holonomic)/diagonals/(hyper)elliptic/ hypergeometric/etc. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - COMBINEPIC - - - ERC-2017-STG - - - 759702 - - - - - HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF EV - HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF EV - - - EUR 1 499 625 - - - Towards the Bottom of the Periodic Table - - - EUR 1 499 625 - - - Germany - Germany - - - Research Organisations - Research Organisations - - Actinide and lanthanide chemistry is currently experiencing a renaissance, due to the prospects of obtaining novel materials relevant for applications in chemical synthesis, electronics, materials science, nanotechnology, - biology and medicine. Most of the fascinating properties of the lanthanide and actinide materials are related to the partially filled 4f/5f valence shell and in contrast to the rest of the periodic table, are poorly understood. This includes the - surprising reactivity, magnetic and crystal structure properties and, the rather unpredictable, covalent or ionic nature of their bonds. It is now possible to study the chemistry of the f-block elements using state-of-the-art techniques that were not - available before. Two new synchrotron-based techniques, high energy resolution fluorescence detection (HERFD) X-ray absorption spectroscopy and resonant inelastic X-ray scattering (RIXS), can now provide unprecedented detailed information on - processes such as the electron-electron interactions, hybridization between molecular orbitals, the nature of their chemical bonding, and the occupation and the degree of the f-electron localization. Therefore, I propose to apply these cutting-edge - techniques to advance the fundamental understanding of the lanthanide and actinide nanoparticles, an outstanding problem in materials science, chemistry and environmental science technology. The research will be conducted at the European Synchrotron - (ESRF), at the Rossendorf Beamline (ROBL) dedicated to actinide science, where we recently installed a novel X-ray emission spectrometer with ground-breaking detection limits. The experimental work will be complemented by electronic structure - calculations. The combined experimental and theoretical data will provide an essential knowledge of lanthanide and actinide chemistry, significant for topics of high societal relevance, like green chemistry, renewable energy and catalysis. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - TOP - - - ERC-2017-STG - - - 759696 - - - - - KING'S COLLEGE LONDON - KING'S COLLEGE LONDON - - - EUR 1 495 430 - - - Engineering the Biointerface of Nanowires to Direct Stem Cell Differentiation - - - EUR 1 495 430 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - ENBION will engineer a platform to direct the differentiation of stem cells by developing principles for the rational design of the biointerface of nanowires. - - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - EnBioN - - - ERC-2017-STG - - - 759577 - - - - - OSPEDALE SAN RAFFAELE SRL - OSPEDALE SAN RAFFAELE SRL - - - EUR 1 498 125 - - - Dissecting Cross-Regulatory Interplays in Tumor-Associated Macrophages - - - EUR 1 498 125 - - - Italy - Italy - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Macrophages are specialized innate immune cells with central roles in homeostasis and disease. Upon - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Italy - - - X-TAM - - - ERC-2017-STG - - - 759532 - - - - - INSTITUT FUR MOLEKULARE BIOLOGIE GGMBH - INSTITUT FUR MOLEKULARE BIOLOGIE GGMBH - - - EUR 1 497 750 - - - Dissecting Quality Control Mechanisms of Mislocalized Proteins - - - EUR 1 497 750 - - - Germany - Germany - - - Research Organisations - Research Organisations - - Protein quality control systems maintain a functional proteome through detection and removal of abnormal proteins. While typically only misfolded or damaged molecules are thought of as abnormal, recent work has revealed that - also mislocalized proteins are subject to quality control. Mislocalized proteins are defined as proteins that fail to reach their native compartment or fail to assemble into their native complex, and thus cannot function normally. Protein - mislocalization is a constitutive problem caused by inefficiencies of cellular processes and increases with aging. Proteins can also mislocalize due to mutations, as seen in various metabolic, cardiovascular and neurodegenerative diseases, and some - types of cancer. - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - MisloQC - - - ERC-2017-STG - - - 759427 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 499 844 - - - Into the Eastern Desert of Egypt from the New Kingdom to the Roman period - - - EUR 1 499 844 - - - France - France - - - Research Organisations - Research Organisations - - The desert is a paradox: it is at the same time arid and rich in resources, a margin and an interface. Far from being a no man’s land, it is a social space of linked solidarities. The “Desert Networks” project aims to explore - the reticular organisation of such a zone by focusing on the southern part of the Eastern Desert of Egypt. Located between the Nile and the Red Sea, it has always been a tantalizing region for Egypt and beyond. Its ancient remains are admirably - preserved and ancient sources about and from the region itself are numerous. Yet, the history of its occupation and appropriation remains a static and compartmentalized one. Therefore, the ambition of the project is to cross disciplinary borders and - achieve an epistemological break by working for the first time in and on the Eastern desert as a dynamic object, both from a long-term perspective (mid-second millennium BC - late third century AD), and by analysing the patterns and functions of the - different networks that linked its various nodes using the connectivity theory that reshaped scholarly paradigms for the Mediterranean in the 2000s. As the head of the French Eastern Desert mission, the PI will co-ordinate a multidisciplinary team. - For the first time, the project will gather all the data unearthed in the region over 300 years, as well as the expected data from the excavations conducted by the project, in a database linked with a GIS. A collaborative and online open access map - of the Eastern Desert will be created and will serve for the spatial analyses and rendering of the real, economic and social networks in the area. These networks evolved over time and through a shifting geography, as people experienced different - perceptions of space. By assessing all these facets and confronting the archaeological material and written evidence, our final objective is to write a new history of the Eastern Desert from Pharaonic to Roman times, focusing on its networks and - evaluating their meaning. - - 2022-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - Desert Networks - - - ERC-2017-STG - - - 759078 - - - - - STOCKHOLMS UNIVERSITET - STOCKHOLMS UNIVERSITET - - - EUR 1 091 249,39 - - - Topology of moduli spaces of Riemann surfaces - - - EUR 1 091 249,39 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The proposal describes two main projects. Both of them concern cohomology of moduli spaces of Riemann surfaces, but the aims are rather different. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Sweden - - - MODULISPACES - - - ERC-2017-STG - - - 759082 - - - - - UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA - BCAM - BASQUE CENTER FOR APPLIED MATHEMATICS - INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE - BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION - UNIVERSITAT POLITECNICA DE CATALUNYA - REPSOL SA - PONTIFICIA UNIVERSIDAD CATOLICA DE VALPARAISO - CURTIN UNIVERSITY OF TECHNOLOGY - THE UNIVERSITY OF TEXAS SYSTEM - UNIVERSIDAD NACIONAL DE COLOMBIA - PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE - UNIVERSIDAD CENTRAL DE VENEZUELA - UNIVERSIDAD DE BUENOS AIRES - MACQUARIE UNIVERSITY - - - EUR 765 000 - - - Multiscale Inversion of Porous Rock Physics using High-Performance Simulators: Bridging the Gap between Mathematics and Geophysics - - - EUR 765 000 - - - Spain - Spain - France - Spain - Spain - Spain - Chile - Australia - United States - Colombia - Chile - Venezuela - Argentina - Australia - - - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - We will develop and exchange knowledge on applied mathematics, high-performance computing (HPC), and geophysics to better characterize the Earth´s subsurface. We aim to better understand porous rocks physics in the context of - elasto-acoustic wave propagation phenomena. We will develop parallel high-continuity isogeometric analysis (IGA) simulators for geophysics. We will design and implement fast and robust parallel solvers for linear equations to model multi-physics - electromagnetic and elasto-acoustic phenomena. We seek to develop a parallel joint inversion workflow for electromagnetic and seismic geophysical measurements. To verify and validate these tools and methods, we will apply the results to: characterise - hydrocarbon reservoirs, determine optimal locations for geothermal energy production, analyze earthquake propagation, and jointly invert deep-azimuthal resistivity and elasto-acoustic borehole measurements. - - - 2022-03-31, Grant Agreement signed - - - 2018-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Spain - - - MATHROCKS - - - H2020-MSCA-RISE-2017 - - - 777778 - - - - - POLITECHNIKA SLASKA - UNIVERSITY OF GLASGOW - UNIVERSITY OF DURHAM - HEINRICH-HEINE-UNIVERSITAET DUESSELDORF - OSAKA UNIVERSITY - NATIONAL TAIWAN UNIVERSITY - UNIVERSIDADE FEDERAL DE SANTA CATARINA. - - - EUR 832 500 - - - Organic Charge Transfer Applications - - - EUR 1 183 500 - - - Poland - United Kingdom - United Kingdom - Germany - Japan - Taiwan - Brazil - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Organic molecules are everywhere, they are integral to life, from every living species to new technologies such as organic electronics. Organic molecules can be made with infinite variety and what happens when they are excited - by light is just as varied and complex. Molecular shape and molecular interactions are important in their application but what happens to them once excited is just as critical and often defines the function of that molecular within a more complex - system. One of very interesting phenomena in organic molecules is electron transfer (ET) to form stable Charge Transfer excited states (CT). We may observe CT states everywhere, from living tissue to organic solar cells or organic light emitting - diodes. It is believed that birds use CT states to navigate. It is therefore crucial to understand the ET process and the CT state. CT states, bound electron and hole pairs, separated in space on different parts of a molecules or different molecules - play an ever increasing role in organic optoelectronic devices be they OPV or OLED or in bioimaging. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Poland - - - OCTA - - - H2020-MSCA-RISE-2017 - - - 778158 - - - - - UNIWERSYTET WARSZAWSKI - UNIWERSYTET WARSZAWSKI - - - EUR 1 484 854 - - - Urban Metamorphosis of the community of a Medieval African capital city - - - EUR 1 484 854 - - - Poland - Poland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - UMMA (Arab. أمة - community) is a multidisciplinary project aimed as the first study of the liminal phases of a Christian African community inhabiting Dongola, the capital city of of Makuria (modern Sudan). It will concern the - twilight of Christian Dongola and the metamorphosis of its urban community into a new entity organised along different social and religious paradigms. The project will investigate the impact between the weakening of the central authority and - migrations of Islamic Arab tribes on the kingdom’s capital city and its community. The notion that the project intends to investigate is that a complete breakdown of this urban organism and its hinterland was avoided thanks to cooperation established - between the remaining local community and migrant population groups arriving in the period under consideration. The project will seek to identify strategies of - - 2023-05-31, Grant Agreement signed - - - 2018-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Poland - - - UMMA - - - ERC-2017-STG - - - 759926 - - - - - THE UNIVERSITY OF EDINBURGH - THE UNIVERSITY OF EDINBURGH - - - EUR 1 498 915 - - - Stereoretentive-Enantioconvergent Catalysis: A New Concept in Asymmetric Synthesis - - - EUR 1 498 915 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project will experimentally establish a new concept in asymmetric synthesis: stereoretentive-enantioconvergent catalysis. This will represent a completely new method for accessing enantiopure materials starting from - racemic substrates and will therefore impact all areas of synthetic chemistry. The ability to synthesise chiral molecules in enantiopure form is vitally important, most recognisably for the pharmaceutical industry. This is because the molecules of - life are chiral (e.g., D-sugars and L-amino acids) and enantiomers often interact very differently with living organisms. Classically, asymmetric synthesis utilising racemic substrates is limited to achieving a maximum yield of 50% (e.g., kinetic - resolutions). Enantioconvergent catalysis avoids this limitation with both enantiomers of the starting material being converted into a single enantioenriched product, thanks to complex stereoablative or stereomutative de-racemisation processes. This - project will establish a conceptually new stereoretentive-dimerisation approach that results in both enantiomers of the starting material being incorporated into the product with no de-racemisation required. This new concept will prove highly - valuable for the synthesis of small enantiopure building blocks, which will be of high value in many areas of synthesis, and also for more complex late-stage transformations in complex molecule synthesis. Several approaches will be pursued to - demonstrate proof-of-principle, and applications in the synthesis of complex natural and unnatural products will then be used to demonstrate the potential of stereoretentive-enantioconvergent catalysis in target-orientated synthesis. - - 2022-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - SEC - - - ERC-2017-STG - - - 759552 - - - - - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - - - EUR 1 500 000 - - - Principles of Musical Structure Building: Theory, Computation, and Cognition - - - EUR 1 500 000 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Music is a central human trait across all cultures and historical periods, involving a great rich variety of parameters, cognitive processes, and forms of structure building. The proposed project aims at advancing the - understanding of human cognition and, specifically, the capacity to represent and process complex auditory sequences and syntactic structures by exploring the rich potential of music perception. - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Switzerland - - - PMSB - - - ERC-2017-STG - - - 760081 - - - - - THE UNIVERSITY OF EDINBURGH - THE UNIVERSITY OF EDINBURGH - - - EUR 1 499 351 - - - Energy transfer Processes at gas/wall Interfaces under extreme Conditions - - - EUR 1 499 351 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In the future, high-efficiency (low CO2) vehicles will be powered in part by reinvented internal combustion (IC) engines that are “downsized” and operate with new combustion modes. These engine concepts are subject to problems - such as increased transient heat transfer and flame quenching in small passages. Near-wall transient heat transfer is not well-understood in engine environments; the gas is not constant in pressure, temperature, or velocity such that physical - processes quickly digress from established theory. EPIC is uniquely placed to address these problems. A novel constant-volume chamber, offering realistic engine passages but with optical access, and which emulates the pressure/temperature time curve - of a real engine, will be developed. This chamber will make it possible to measure the highly transient and highly variable processes at the gas/wall interface (including a highly dynamic flame front) for single- and two-wall passages. Measurements - will be made using a suite of advanced laser diagnostics; a novel aspect of the proposed work as they have not been used in combination to study such a problem before. Hybrid fs/ps rotational coherent Raman (i.e. CARS) in a line format will provide - transient gas temperature and species profiles normal to the wall surface in high-risk/high-gain packages. PIV/PTV measurements will further elucidate flow dynamics at the surface. Planar OH-LIF will help interpret CARS measurements and provide - necessary details of flame transport and quenching. As the flame approaches the surface, phosphor thermometry will measure wall temperature and heat flux to elucidate the highly dynamic inter-coupling between flame and wall. EPIC will provide - substantial breakthroughs in knowledge by measuring unsteady boundary layer development and understanding its influence on flame quenching for single- and two-wall surfaces. As such, EPIC will provide the fundamental knowledge that supports cleaner - combustion technology for the future. - - 2022-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - EPIC - - - ERC-2017-STG - - - 759546 - - - - - UNIVERSITA DEGLI STUDI DI MILANO - UNIVERSITA DEGLI STUDI DI MILANO - - - EUR 1 500 000 - - - Eradicating Chronic Infections - - - EUR 1 500 000 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Given the alarming progression of chronic and relapsing infections in the last decades, and the even more alarming predictions for the upcoming years, it is urgent for chemists to be able to provide new molecular tools to - study, and ultimately solve, these complex biological problems. Bacterial persisters are an elusive "dormant" phenotype that play a pivotal role in chronic infections, with mechanisms that remain to be fully unravelled. Current knowledge suggests - that bacterial persisters are not genetically resistant to antibiotic treatment; they simply appear to shut down through a cascade of biochemical events called the stringent response (SR), becoming insensitive to current drugs. This subpopulation - remains unaffected during the time of pharmacological treatment and represents a reservoir that sustains pathogen survival and resurgence. The goal of this project is to fill the knowledge gap between persisters formation and infection eradication, - providing the community with potent and selective small molecular tools that can be used to challenge complementary survival mechanisms. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Italy - - - ERACHRON - - - ERC-2017-STG - - - 758108 - - - - - UNIVERSITETET I TROMSOE - UNIVERSITETET I TROMSOE - - - EUR 1 499 749 - - - Cryptophane-Enhanced Trace Gas Spectroscopy for On-Chip Methane Detection - - - EUR 1 499 749 - - - Norway - Norway - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Sensitivity of on-chip gas sensors is still at least 2-3 orders of magnitude lower than what is needed for applications in atmospheric monitoring and climate research. For optical sensors, this comes as a natural consequence - of miniaturization: sensitivity scales with interaction length, which is directly related to instrument size. The aim of this project is to explore a new concept of combined chemical and spectroscopic detection for on-chip sensing of methane, the - principal component of natural gas and a potent climate forcer. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Norway - - - sCENT - - - ERC-2017-STG - - - 758973 - - - - - UNIVERSITA DEGLI STUDI DI PADOVA - EOTVOS LORAND TUDOMANYEGYETEM - VRIJE UNIVERSITEIT BRUSSEL - UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN - EUROPEAN MOLECULAR BIOLOGY LABORATORY - UNIVERSIDAD NACIONAL DE QUILMES - FUNDACION INSTITUTO LELOIR - UNIVERSIDAD NACIONAL DE GENERAL SAN MARTIN - - - EUR 1 291 500 - - - Driving the functional characterization of intrinsically disordered proteins - - - EUR 1 291 500 - - - Italy - Hungary - Belgium - Ireland - Germany - Argentina - Argentina - Argentina - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - - Intrinsically disordered proteins (IDPs), characterized by high conformational variability and interaction promiscuity, defy the classic protein structure-function paradigm. IDPs cover almost half of the residues in Eukaryotic - proteomes. Growing evidence suggests that IDPs, interacting with multiple partners, are major players in cellular regulation and involved in numerous human diseases. Computational methods have contributed to the identification of IDPs from sequence - and recently published curated IDP databases provide a starting point. However, functional knowledge for IDPs remains very limited. - - 2022-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Italy - - - IDPfun - - - H2020-MSCA-RISE-2017 - - - 778247 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - - - EUR 1 333 325 - - - Open dynamics of interacting and disordered quantum systems - - - EUR 1 333 325 - - - Ireland - Ireland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This research proposal focuses on the open quantum system dynamics of disordered and interacting many- body systems coupled to external baths. The dynamics of systems which contain both disorder and interactions are currently - under intense theoretical investigation in condensed matter physics due to the discovery of a new phase of matter known as many-body localization. With the experimental realization of such systems in mind, this proposal addresses an essential issue - which is to understand how coupling to external degrees of freedom influences dynamics. These systems are intrinsically complex and lie beyond the unitary closed system paradigm, so the research proposed here contains interdisciplinary methodology - beyond the mainstream in condensed matter physics ranging from quantum information to quantum optics. The project has three principal objectives each of which would represent a major contribution to the field: - - 2023-06-30, Grant Agreement signed - - - 2018-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Ireland - - - ODYSSEY - - - ERC-2017-STG - - - 758403 - - - - - Institute of Science and Technology Austria - Institute of Science and Technology Austria - - - EUR 1 500 000 - - - A Fiber Optic Transceiver for Superconducting Qubits - - - EUR 1 500 000 - - - Austria - Austria - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Many researchers in basic science and large IT companies are convinced that superconducting quantum processors will soon help solve complex problems faster, improve optimization and simulation, and boost the progress in - artificial intelligence. A worldwide quantum web is the next logical step. It would not only improve communication security, it represents the key to unlock the full potential of the new quantum-computing paradigm. - - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Austria - - - QUNNECT - - - ERC-2017-STG - - - 758053 - - - - - KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN - KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN - - - EUR 1 499 403,74 - - - The neuroenergetics of memory consolidation – hybrid PET/MR imaging of the default mode network - - - EUR 1 499 403,74 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Since its discovery more than a decade ago, the most studied network in the human brain remains a paradox. The default mode network (DMN) is most active during the resting state and deactivates once subjects engage in goal - directed behavior. Although reported in hundreds of studies using functional magnetic resonance imaging (fMRI), the function of the DMN is still unknown. I hypothesize that memories are consolidated in the DMN during resting state, a process that is - interrupted once we engage in cognitive processing. This hypothesis is based on two complementary and recent findings. First, brain regions involved in encoding of novel or retrieval of consolidated memories strongly resemble regions of the DMN. - Second, the DMN consumes most glucose during resting state as revealed by positron emission tomography (PET). Importantly, energy in the brain is mainly dedicated to neuronal signaling and synaptic plasticity related to memory consolidation. - - 2023-06-30, Grant Agreement signed - - - 2018-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - SUGARCODING - - - ERC-2017-STG - - - 759659 - - - - - UNIVERSITE CATHOLIQUE DE LOUVAIN - UNIVERSITE CATHOLIQUE DE LOUVAIN - - - EUR 1 302 710 - - - BIOMIMETIC FIXATION OF CO2 AS SOURCE OF SALTS AND GLUCOSE - - - EUR 1 302 710 - - - Belgium - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The continued increase in the atmospheric concentration of CO2 due to anthropogenic emissions is leading to significant changes in climate, with the industry accounting for one-third of all the energy used globally and for - almost 40% of worldwide CO2 emissions. Fast actions are required to decrease the concentration of this greenhouse gas in the atmosphere, value that has currently reaching 400 ppm. Among the technological possibilities that are on the table to reduce - CO2 emissions, carbon capture and storage into geological deposits is one of the main strategies that is being applied. However, the final objective of this strategy is to remove CO2 without considering the enormous potential of this molecule as a - source of carbon for the production of valuable compounds. Nature has developed an effective and equilibrated mechanism to concentrate CO2 and fixate the inorganic carbon into organic material (e.g., glucose) by means of enzymatic action. Mimicking - Nature and take advantage of millions of years of evolution should be considered as a basic starting point in the development of smart and highly effective processes. In addition, the use of amino-acid salts for CO2 capture is envisaged as a - potential approach to recover CO2 in the form of (bi)carbonates. - - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Belgium - - - CO2LIFE - - - ERC-2017-STG - - - 759630 - - - - - Eidgenössische Technische Hochschule Zürich - Eidgenössische Technische Hochschule Zürich - - - EUR 1 497 104 - - - Enhancing brain function and cognition via artificial entrainment of neural oscillations - - - EUR 1 497 104 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Neural oscillations are ubiquitous in the human brain and have been implicated in diverse cognitive functions to support both neural communication and plasticity. Their functional relevance is further supported by a large - number of studies linking various cognitive deficits (e.g., attention deficit hyperactivity disorder, ADHD) with abnormal neural oscillations. However, this field of research faces two important problems: First, there is only correlative, but no - causal evidence linking cognitive deficits to abnormal neural oscillations in humans. Second, there is virtually no theory-driven mechanistic approach that generates insights into how oscillations within and across neural networks are linked to human - behavior. In this project, I propose to take decisive steps to provide a long-needed neurophysiological characterization—via (1) computational modelling, (2) electrophysiological measures, and (3) novel non-invasive manipulations of cortical - rhythms—on how neural oscillations contribute to two types of cognitive processes that are fundamental for many aspects of human behavior: attention and short-term memory. I will go a step further by demonstrating that it is possible to augment - performance in these cognitive functions with the design of non-invasive brain stimulation protocols individually tailored to the theory-driven neurocomputational characterizations and electrophysiological signatures of each individual. This will - result in the applied goal of deriving new neuro-computational assays that can detect deviant network interactions causally related to cognitive functions, which is key for then renormalizing those functions in neuropsychological conditions such as - ADHD. Thus, if successful, my proposed work will ultimately result in novel, low-cost, and painless non-invasive neural interventions for a wide range of neuropsychological disorders tied to abnormal neural oscillations. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Switzerland - - - ENTRAINER - - - ERC-2017-STG - - - 758604 - - - - - VIB - VIB - - - EUR 1 706 250 - - - The role of sleep in synaptic plasticity - - - EUR 1 706 250 - - - Belgium - Belgium - - - Research Organisations - Research Organisations - - Although we spend a third of our lives sleeping, the function of sleep remains mysterious. Studies considering neural networks, brain regions and behavior suggest the intriguing hypothesis that sleep is important for synaptic - plasticity. However, as prior studies have conducted analyses using broad brain regions or circuit networks, the precise role of sleep in synaptic plasticity remains intensely debated. Progress in this area is hindered by the lack of a - genetically-tractable system of sleep-dependent synaptic plasticity. To solve this, I developed a unique fruit fly model. It is the first model of its kind in which the cellular players comprising the synapses can be genetically labelled and - manipulated. I will use this model to address a long-running controversy in the field--which form(s) of synaptic plasticity is promoted by sleep--by directly monitoring the effects of sleep on precisely identified synapses at electrophysiological and - ultrastructural levels. Then, I will investigate the mechanisms underlying this process by analyzing the effects of sleep on every cellular component (pre and postsynaptic neurons and perisynaptic astrocytes) in this model at molecular and cellular - levels. Emerging data suggest that astrocytes play a key role in synaptic plasticity and have further implicated these cells in regulating sleep. However, it has been difficult to directly examine the role of astrocytes in sleep-dependent synaptic - plasticity, since no methodology currently exists for reproducibly manipulating local astrocytes enveloping the synapse of interest. For this, I will implement a unique tool, named G-CLAMP, and use it to assess potential glial mechanisms underlying - sleep-dependent plasticity. Considered as a whole, my project will produce unique and comprehensive understanding of the role of sleep in synaptic plasticity, an essential question if we aim to understand sleep, and move us towards explaining the - evolutionarily origins of this mysterious behavior. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Belgium - - - SleepSynapses - - - ERC-2017-STG - - - 758580 - - - - - ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA - UNIVERSIDAD AUTONOMA DE MADRID - UNIVERSIDAD DE GRANADA - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSITE PARIS-SUD - Marposs SpA - GMV AEROSPACE AND DEFENCE SA - TRUSTEES OF PRINCETON UNIVERSITY - THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - MASSACHUSETTS INSTITUTE OF TECHNOLOGY - YALE UNIVERSITY - JOHNS HOPKINS UNIVERSITY - UNIVERSITY OF PITTSBURGH - UNIVERSITY OF HOUSTON SYSTEM - THE UNIVERSITY OF TEXAS SYSTEM - THE WASHINGTON UNIVERSITY CORPORATION - WORCESTER POLYTECHNIC INSTITUTE - UNIVERSIDAD DE BUENOS AIRES - ACADEMIA SINICA - - - EUR 1 782 000 - - - Geometric and Harmonic Analysis with Interdisciplinary Applications - - - EUR 1 930 500 - - - Italy - Spain - Spain - France - France - Italy - Spain - United States - United States - United States - United States - United States - United States - United States - United States - United States - United States - Argentina - Taiwan - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - GHAIA will promote excellence through mobility to the world leader Universities in pure and applied mathematical research: Princeton University, Mit, Yale, Johns Hopkins, the Universities of California, of Texas, of Houston, - of Pittsburgh, the Washington University (St. Louis), and the Worchester Polytechnical Institute, the Academia Sinica, the University of Buenos Aires have joined the consortium. European researchers will have the extraordinary opportunity to work in - their exciting environment as well as receiving visiting researchers from south America. Moreover two selected enterprises have joined the consortium, allowing intersectorial mobility: Marposs and GMV, leaders in the strategic sectors of EU industry - of precision equipments for automatic inspection, and of satellite navigation. - - 2021-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Italy - - - GHAIA - - - H2020-MSCA-RISE-2017 - - - 777822 - - - - - UNIVERSITA DEGLI STUDI DI PADOVA - UNIVERSITA DEGLI STUDI DI PADOVA - ISTITUTO NAZIONALE DI GEOFISICA E VULCANOLOGIA - - - EUR 1 466 030 - - - NEw Windown inTO Earth's iNterior - - - EUR 1 466 030 - - - Italy - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - Comprehensive seismic programs undertaken in the past few years, combined with emerging new numerical technologies now provide the potential, for the first time, to explore in detail the Earth’s interior. However, such an - integrated approach is currently not contemplated, which produces physical inconsistencies among the different studies that strongly bias our understanding of the Earth’s internal structure and dynamics. Of particular concern are nowadays apparent - thermo-petrological anomalies in tomographic images that are generated by the unaccounted-for anisotropic structure of the mantle and that are commonly confused with real thermo-petrological features. Given the diffuse mantle seismic anisotropy, - apparent thermo-petrological anomalies contaminate most tomographic models against which tectono-magmatic models are validated, representing a critical issue for the present-day window. - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Italy - - - NEWTON - - - ERC-2017-STG - - - 758199 - - - - - UNIVERSITAT AUTONOMA DE BARCELONA - KAROLINSKA INSTITUTET - ACIB GmbH - AB BCN S.L. - QUALIZYME DIAGNOSTICS GMBH & CO KG - STOCKHOLMS LANS LANDSTING - - - EUR 504 000 - - - New Selenium-based Targeted Nanocapsules to treat Breast Cancer - - - EUR 504 000 - - - Spain - Sweden - Austria - Spain - Austria - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - The European Chronic Diseases Alliance has defined cancer as one of the major non-communicable diseases, accounting for 13% of the deaths worldwide, resulting in 8.2 million deaths annually. In the NEOSETAC project, breast - cancer will be the focus of study being the most common cancers in women. It comprises of 10.4% of all the cancer incidences among women, causing 411 093 deaths per year overall the world. In Europe, there is more than twice of the amount of new - breast cancer cases annually than new cases of cancer in any other place. The complexity of breast cancer makes it a big challenge for successful treatment. The NEOSETAC project will demonstrate the anti-cancer therapeutic potential of a novel - Seleniumbased therapy for the management of breast cancer. The clinical application of Selenium (Se) compounds for cancer treatment is until now limited in chemoprevention as dietary supplement. In this proposal, we aim to improve the therapeutic - window, pharmacokinetic properties and targeting drug delivery via nanoparticles (NPs). By loading Se into biodegradable NPs, drug release is controlled within the narrow therapeutic window of Se. At the same time the uptake and activation of Se - compounds at desired location (tumor lesions and metastasis) is achieved. We also propose to functionalize NPs by cancer cell / cancer stem cell targeting ligands to further improve the therapeutic efficacy and prevent cancer recurrence after - chemotherapy. These advantages will lead to an enhanced anticancer activity and reduced systemic toxicity. Moreover, targeting via NPs will improve the pharmacokinetic properties and increase the relatively short half-life (~18 hours) of Se. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Spain - - - NEOSETAC - - - H2020-MSCA-RISE-2017 - - - 778325 - - - - - ROYAL COLLEGE OF SURGEONS IN IRELAND - ROYAL COLLEGE OF SURGEONS IN IRELAND - - - EUR 1 372 135 - - - Bilayered ON-Demand Scaffolds: On-Demand Delivery from induced Pluripotent Stem Cell Derived Scaffolds for Diabetic Foot Ulcers - - - EUR 1 372 135 - - - Ireland - Ireland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This program’s goal is to develop a scaffold using a new biomaterial source that is functionalised with on-demand delivery of genes for coordinated healing of diabetic foot ulcers (DFUs). DFUs are chronic wounds that are often - recalcitrant to treatment, which devastatingly results in lower leg amputation. This project builds on the PI’s experience growing matrix from induced-pluripotent stem cell derived (iPS)-fibroblasts and in developing on-demand drug delivery - technologies. The aim of this project is to first develop a SiPS: a scaffold from iPS-fibroblast grown matrix, which has never been tested as a source material for scaffolds. iPS-fibroblasts grow a more pro-repair and angiogenic matrix than (non-iPS) - adult fibroblasts. The SiPS structure will be bilayered to mimic native skin: dermis made mostly by fibroblasts and epidermis made by keratinocytes. The dermal layer will consist of a porous scaffold with optimised pore size and mechanical properties - and the epidermal layer will be film-like, optimised for keratinisation. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Ireland - - - BONDS - - - ERC-2017-STG - - - 758064 - - - - - TEL AVIV UNIVERSITY - TEL AVIV UNIVERSITY - - - EUR 1 499 528 - - - Supervised Verification of Infinite-State Systems - - - EUR 1 499 528 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Modern society relies more and more on computing for managing complex safety-critical tasks (e.g., in medicine, avionics, economy). Correctness of computerized systems is therefore crucial, as incorrect behaviors might lead to - disastrous outcomes. Still, correctness is a big open problem without satisfactory theoretical or practical solutions. This has dramatic effects on the security of our lives. The current practice in industry mainly employs testing which detects bugs - but cannot ensure their absence. In contrast, formal verification can provide formal correctness guarantees. Unfortunately, existing formal methods are still limited in their applicability to real world systems since most of them are either too - automatic, hindered by the undecidability of verification, or too manual, relying on substantial human effort. This proposal will introduce a new methodology of supervised verification, based on which, we will develop novel approaches that can be - used to formally verify certain realistic systems. This will be achieved by dividing the verification process into tasks that are well suited for automation, and tasks that are best done by a human supervisor, and finding a suitable mode of - interaction between the human and the machine. Supervised verification represents a conceptual leap as it is centered around automatic procedures but complements them with human guidance; It therefore breaks the classical pattern of automated - verification, and creates new opportunities, both practical and theoretical. In addition to opening the way for developing tractable verification algorithms, it can be used to prove lower and upper bounds on the asymptotic complexity of verification - by explicitly distilling the human's role. The approaches developed by this research will significantly improve system correctness and agility. At the same time, they will reduce the cost of testing, increase developers productivity, and improve the - overall understanding of computerized systems. - - 2023-03-31, Grant Agreement signed - - - 2018-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Israel - - - SVIS - - - ERC-2017-STG - - - 759102 - - - - - UNIVERSITAT AUTONOMA DE BARCELONA - LUNDS UNIVERSITET - UNIVERSITE DE PAU ET DES PAYS DE L'ADOUR - UNIVERSITA DEGLI STUDI DI UDINE - AERIS TECNOLOGÍAS AMBIENTALES S.L. - EUROPE FOR BUSINESS LTD - UNIVERSIDAD DE LA HABANA - CENTRO DE INVESTIGACION Y DESARROLLO DE MEDICAMENTOS - - - EUR 895 500 - - - Removal and Recovery of Pharmaceutical Persistent Pollutants from Wastewater by Selective Reagentless Process - - - EUR 895 500 - - - Spain - Sweden - France - Italy - Spain - United Kingdom - Cuba - Cuba - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Pharmaceutical drugs, characterized by their environmental persistence (e.g. cytostatic drugs [CDs]) have been detected in water bodies (drinking water, groundwater, surface water, and effluent wastewater) at concentrations up - to μg/L level. Actual methods for the removal and degradation of CDs, including electrochemical, photochemical, and biological methods have been developed. However, these methods are expensive and sometimes inefficient for CDs complete removal from - the treated water. Including the exploitation of previous results from EU funded projects, the goal of project RECOPHARMA is to design, develop, validate and demonstrate a novel process by sequential integration the potentials offered by Molecular - Imprinted Polymers (MIPs), Reagentless Thermosorption (RTS), Nanocomposites Functional Materials, Advanced Oxidation Processes, for an effective treatment aiming the recovery of target recalcitrant CDs and degradation of corresponding transformation - products or metabolites, working in a continuous operation mode. The suggested approach offers versatile, fast, highly efficient, and low-cost treatment for wastewaters. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Spain - - - RECOPHARMA - - - H2020-MSCA-RISE-2017 - - - 778266 - - - - - KAROLINSKA INSTITUTET - KAROLINSKA INSTITUTET - - - EUR 1 812 500 - - - Flame nanoengineering for antibacterial medical devices - - - EUR 1 812 500 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Engineers in nanotechnology research labs have been quite innovative the last decade in designing nanoscale materials for medicine. However, very few of these exciting discoveries are translated to commercial medical products - today. The main reasons for this are two inherent limitations of most nanomanufacture processes: scalability and reproducibility. There is too little knowledge on how well the unique properties associated with nanoparticles are maintained during - their large-scale production while often poor reproducibility hinders their successful use. A key goal here is to utilize a nanomanufacture process famous for its scalability and reproducibility, flame aerosol reactors that produce at tons/hr - commodity powders, and advance the knowledge for synthesis of complex nanoparticles and their direct integration in medical devices. Our aim is to develop the next generation of antibacterial medical devices to fight antimicrobial resistance, a - highly understudied field. Antimicrobial resistance constitutes the most serious public health threat today with estimations to become the leading cause of human deaths in 30 years. - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Sweden - - - PROMETHEUS - - - ERC-2017-STG - - - 758705 - - - - - UNIVERSITY OF BRISTOL - UNIVERSITY OF BRISTOL - - - EUR 1 414 722 - - - Legitimacy, Financialization, and Varieties of Capitalism: Understanding Sovereign Wealth Funds in Europe - - - EUR 1 414 722 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The number and size of sovereign wealth funds (SWF) has grown substantially in the last decade, leading to an unsettled debate regarding their legitimacy in the global political economy. Some suggest they represent the - (re)emergence of state-led capitalism subject to geopolitical motivations that threaten free markets. For others, SWFs represent a source of long-term patient capital capable of mitigating market short-termism. Either way, SWFs challenge the norm, - particularly in the West, that financial markets are spaces of exchange for non-state actors. In three complementary and interdisciplinary work programmes the SWFsEUROPE project will explain the evolving and variegated pattern of ‘sovereign fund - capitalism’ in Europe, developing a new theory of the relationship between states and global finance. First, the project breaks new ground by explaining and theorizing how the legitimacy of SWFs as commercially oriented investors is performed when - they are still entities of the state. No study has critically examined how legitimacy is performed via mechanisms such as the International Forum of Sovereign Wealth Funds and the Santiago Principles, or the growing evidence of collaboration with - cognate institutional investors (e.g. pension funds). Second, this projects seeks a multi-layered explanation of the uneven pattern of investment flows and stocks of foreign SWFs into European countries through hypothesis testing of aggregate - investment data with different theories of national-institutional variety, coupled with a comparative analysis of the bilateral investment-promotion relationships of investment-receiving countries. Third, the project will compare the growth and - development of European SWFs. There is no comparative study exploring why some states are sponsors of an SWF (e.g. Italy, France, Ireland) and others are not (e.g. UK), what the motivations are and how they are made legitimate. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - SWFsEUROPE - - - ERC-2017-STG - - - 758430 - - - - - FUNDACIO INSTITUT DE RECERCA DE L'ENERGIA DE CATALUNYA - STIFTELSEN SINTEF - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSIDAD AUTONOMA DE MADRID - Institute of Applied Physics of the Academy of Sciences of Moldova - HELMHOLTZ-ZENTRUM BERLIN FUR MATERIALIEN UND ENERGIE GMBH - SOCIETATEA CU RASPUNDERE LIMITATA SUNGA - UAB MODERNIOS E-TECHNOLOGIJOS - MOROCCAN FOUNDATION FOR ADVANCED SCIENCE INNOVATION AND RESEARCHFONDATION MASCIR - BELARUSSKY GOSUDARSTVENNIY UNIVERSITET INFORMATIKI I RADIOELEKTRONIKI - UNIVERSITE MOHAMMED V DE RABAT - UNIVERSITY OF THE WESTERN CAPE - - - EUR 1 318 500 - - - International cooperation for the development of cost-efficient kesterite/c-Si thin film next generation tandem solar cells - - - EUR 1 318 500 - - - Spain - Norway - France - Spain - Moldova - Germany - Moldova - Lithuania - Morocco - Belarus - Morocco - South Africa - - - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Photovoltaic (PV) is recognized as one of the main renewable energy solutions for fulfilling the targets defined by the EU Energy Roadmap 2050 and the SET Plan. Most of the current commercial PV devices are formed by single - junctions, and more complex device concepts allowing a significant increase in device efficiency (well beyond the theoretical limit in the 30%-33% range) are still mostly limited to expensive III-V technologies. - - 2021-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Spain - - - INFINITE-CELL - - - H2020-MSCA-RISE-2017 - - - 777968 - - - - - MAGYAR TUDOMANYOS AKADEMIA SZEGEDIBIOLOGIAI KUTATOKOZPONT - MAGYAR TUDOMANYOS AKADEMIA SZEGEDIBIOLOGIAI KUTATOKOZPONT - - - EUR 1 486 500 - - - The genetic basis of the convergent evolution of fungal multicellularity - - - EUR 1 486 500 - - - Hungary - Hungary - - - Research Organisations - Research Organisations - - The evolution of multicellularity (MC) has been one of the major transitions in the history of life. Despite immense interest in its evolutionary origins, the genomic changes leading to the emergence of MC, especially that of - complex MC (differentiated 3-dimensional structures) are poorly known. Previous comparative genomics projects aiming to understand the genetic bases of MC in one way or another relied on gene content-based analyses. However, a pattern emerging from - these studies is that gene content provides only an incomplete explanation for the evolution of MC even at ancient timescales. We hypothesize that besides gene duplications, changes to cis-regulatory elements and gene expression patterns (including - protein isoforms) have significantly contributed to the evolution of MC. To test this hypothesis, we will deploy a combination of computational methods, phylogenomics, comparative transcriptomics and genome-wide assays of regulatory elements. Our - research focuses on fungi as a model system, where complex MC evolved convergently and in subsequent two steps. Fungi are ideal models to tackle this question for several reasons: a) multicellularity in fungi evolved multiple times, b) there are rich - genomic resources (>500 complete genomes), c) complex multicellular structures can be routinely grown in the lab and d) genetic manipulations are feasible for several cornerstone species. We set out to examine which genes participate in the - building of simple and complex multicellular structures and whether the evolution of regulome complexity and gene expression patterns can explain the evolution of MC better than can traditionally assayed sources of genetic innovations (e.g. gene - duplications). Ultimately, our goal is to reach a general synthesis on the genetic bases of the evolution of MC and that of organismal complexity. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Hungary - - - Multicellularity - - - ERC-2017-STG - - - 758161 - - - - - UNIVERSITEIT VAN AMSTERDAM - UNIVERSITEIT VAN AMSTERDAM - - - EUR 1 499 750 - - - From the Expression of Disagreeement to New Foundations for Expressivist Semantics - - - EUR 1 499 750 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Disagreement is a pervasive feature of human life, which finds linguistic expression in the speech-act of rejection. If you assert that Amsterdam is in Belgium, I can express my dissent by responding 'No', thereby rejecting your assertion. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - EXPRESS - - - ERC-2017-STG - - - 758540 - - - - - BIOSENSE INSTITUTE - RESEARCH AND DEVELOPMENT INSTITUTE FOR INFORMATION TECHNOLOGIES IN BIOSYSTEMS - BEONCHIP SL - UNIVERSIDAD DE ZARAGOZA - CHERRY BIOTECH - UNIWERSYTET JAGIELLONSKI - ELVESYS SAS - RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY - - - EUR 364 500 - - - Heart On chip based on induced pluripotent Stem cell Technology for personalized Medicine - - - EUR 364 500 - - - Serbia - Spain - Spain - France - Poland - France - United States - - - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - Many rare diseases cause chronic health problems or are even life-threatening. The impact on the quality of life of affected patients, of whom many are children, is significant. To date, a limited but increasing number of - so-called orphan drugs (drugs for rare diseases) are reaching patients. However, the majority of rare diseases are still without any effective treatment. The development of novel human systems for drug discovery therefore represents a major public - health priority. Microfluidic technology-based “Organs-on-a-chip” represents a powerful tool for investigating rare disease mechanisms and testing new drug and treatment due to their ability to mimic tailored micro-environment architecture inspired - by organ-level functions in vivo. However, due to the variability in rare disease mechanisms from one patient to another, organ on chip technology needs to be more precise and to convey towards personalized medicine. The human-induced pluripotent - stem cells (iPSCs) have a strong potential in engineering organ-on-a-chip since they are derived in a patient-matched manner which makes them a superb source to construct human models for personalized drug screening as well as for understanding - patient-specific fundamentals of diseases. To provide novel miniaturized platform for investigation of rare diseases able to address the burning issues in precision medicine today, CISTEM will bring together and synergistically several highly - promising research directions which are too often investigated separately at the academic level but also at the industrial level. Based on 4 work packages, the CISTEM RISE project will be implemented by exploiting the complementary expertise of its - partners and creating synergies between them through the targeted secondments of staff. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Serbia - - - CISTEM - - - H2020-MSCA-RISE-2017 - - - 778354 - - - - - UNIWERSYTET WROCLAWSKI - SUBSIDIARY COMPANY PRINCETON BIOMOLECULAR RESEARCH LABS - FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG - SARA PHARM SOLUTIONS SRL - UNIVERSITAT WIEN - A.N. NESMEYANOV INSTITUTE OF ORGANOELEMENT COMPOUNDS OF RUSSIAN ACADEMY OF SCIENCES - - - EUR 796 500 - - - Chiroptical, optical and magnetic probes for protein sensing based on cage metal complexes - - - EUR 958 500 - - - Poland - Ukraine - Germany - Romania - Austria - Russia - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The CLATHROPROBES project is devoted to the design and development of novel, highly efficient chiroptical, luminescent, IR, NMR and EPR probes for sensing and structural studies of biomolecules based on cage metal complexes - (clathrochelates and lacunar complexes of spatial tris-diiminate ligands with encapsulated 3d-metal ion) as molecular reporters. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Poland - - - CLATHROPROBES - - - H2020-MSCA-RISE-2017 - - - 778245 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 494 738 - - - Quantum superiority with coherent states - - - EUR 1 494 738 - - - France - France - - - Research Organisations - Research Organisations - - The unique features of quantum mechanics enable communication and computation tasks impossible to achieve by classical means. This opens a tremendous potential for enhancing the power, efficiency and security of everyday - interactions in our information-based society. The quest of the demonstration in physical systems of quantum superiority has led to milestone implementations, most notably of the distribution of secret keys with unconditional security or of - elementary computations such as the efficient sampling of bosonic distributions. - - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - QUSCO - - - ERC-2017-STG - - - 758911 - - - - - UNIVERSITY OF LEEDS - UNIVERSITY OF LEEDS - - - EUR 1 500 000 - - - Unravelling Multi-scale Oral Lubrication Mechanisms (macro-to-nano): A Novel Strategy to Target Satiety - - - EUR 1 500 000 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Obesity is a serious form of malnutrition that is known to have substantial morbidity and mortality consequences. Hence, to directly promote weight management, there is an immense need to design satiety-enhancing foods that - terminate appetite for longer periods after consumption. Although the concept of “satiety cascade” was proposed nearly 20 years ago, the changing dynamics of food properties in the oral mucosa remains the greatest source of uncertainty in food - design. In particular, our quantitative multi-scale understanding of lubrication of the human salivary film when exposed to stimuli from food biomolecules, which in turn can have significant appetite suppression consequences, remains poorly - understood. The key limitation to accurately measure oral lubrication is the lack of tribo-contact surfaces that effectively emulate the oral surfaces (i.e. the soft, slippery mucous-coated human tongue and the upper palate). - - 2022-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - LubSat - - - ERC-2017-STG - - - 757993 - - - - - OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN - OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN - - - EUR 1 499 556 - - - Non-Territorial Autonomy as Minority Protection in Europe: An Intellectual and Political History of a Travelling Idea, 1850-2000 - - - EUR 1 499 556 - - - Austria - Austria - - - Research Organisations - Research Organisations - - Over the past 150 years, non-territorial autonomy has been one of three models for dealing with linguistic or ethnic minorities within several European states. Compared with the other two, i.e. the recognition of minority - rights as individual rights and territorial self-rule, non-territorial autonomy has received little attention. This project proposes to write the first history of non-territorial autonomy as an applied policy tool in minority protection and as an - intellectual concept with a chequered history across Europe. Intellectuals, politicians, and legal scholars across the political spectrum from the far left to the far right supported this idea, although they were aware of the risks of strengthening - national differences by promoting such a collective approach to minority protection. The project explores how this idea of granting cultural rights to a national group as a corporate body within a state, as a means of integrating diverse - nationalities, travelled and transformed throughout the Habsburg Empire from 1850 to the present. We propose to 1) trace the development/circulation of theoretical conceptions and political applications of non-territorial autonomy within the Habsburg - Empire, by mapping the networks of scholars as well as politicians who advocated for it; 2) explain the continuities in the development of the idea, and its manifestations in policies adopted by interwar Central and Eastern European nation states, - where communists, socialists, liberals and fascists alike were able to translate elements of non-territorial autonomy into their ideologies and programs; 3) analyse the treatment of non-territorial autonomy, which was advocated by minority lobby - groups, in international minority protection in the 20th century despite strong opposition to practices based on it by international organisations. We rely on a mixture of historiographical methods developed in nationalism studies to analyse the - idea’s translation in entangled transnational spaces. - - 2023-03-31, Grant Agreement signed - - - 2018-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Austria - - - N-T-AUTONOMY - - - ERC-2017-STG - - - 758015 - - - - - STOCKHOLMS UNIVERSITET - STOCKHOLMS UNIVERSITET - - - EUR 1 475 636 - - - Supergene evolution in a classic plant system - bringing the study of distyly into the genomic era - - - EUR 1 475 636 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Understanding how adaptive combinations of traits are maintained is a central question in evolutionary biology. Supergenes are clusters of genes that can maintain favorable trait combinations because they are inherited as a - unit. Studying supergenes allows us to address fundamental questions on the origin and evolution of complex adaptations and the effects of suppressed recombination, and is therefore of broad significance. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Sweden - - - SuperGenE - - - ERC-2017-STG - - - 757451 - - - - - KATHOLIEKE UNIVERSITEIT LEUVEN - KATHOLIEKE UNIVERSITEIT LEUVEN - - - EUR 1 452 500 - - - Children in Comics: An Intercultural History from 1865 to Today - - - EUR 1 452 500 - - - Belgium - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Owing to their visual essence and status as a popular, modern medium, comics – newspaper strips, comics magazines and graphic novels – provide valuable insight into the transformation of collective consciousness. This project - advances the hypothesis that children in comics are distinctive embodiments of the complex experience of modernity, channeling and tempering modern anxieties and incarnating the freedom denied to adults. In testing this hypothesis, the project - constructs the first intercultural history of children in European comics, tracing the changing conceptualizations of child protagonists in popular comics for both children and adults from the mid-19th century to the present. In doing so, it takes - key points in European history as well as the history of comics into account. - - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Belgium - - - COMICS - - - ERC-2017-STG - - - 758502 - - - - - INSTITUTO NACIONAL DE INVESTIGACIONY TECHNOLOGIA AGRARIA Y ALIMENTARIA OA MP - INSTITUTO NACIONAL DE INVESTIGACIONY TECHNOLOGIA AGRARIA Y ALIMENTARIA OA MP - - - EUR 1 480 880 - - - Gene editing and in vitro approaches to understand conceptus elongation in ungulates - - - EUR 1 480 880 - - - Spain - Spain - - - Research Organisations - Research Organisations - - In contrast to human or rodent embryos, ungulate embryos do not implant into the uterus right after blastocyst hatching. Before implantation, the hatched ungulate blastocyst must undergo dramatic morphological changes - characterized by cell differentiation, proliferation and migration processes leading to the development of extra-embryonic membranes, the appearance of a flat embryonic disc and gastrulation. This prolonged preimplantation development is termed - conceptus elongation and deficiencies on this process constitute the most frequent cause of reproductive failures in ungulates, including the 4 most relevant mammalian livestock species in Europe. The purpose of this project is to elucidate the - factors involved in conceptus elongation by gene editing and in vitro culture approaches. A first objective will be to identify key genes involved in differentiation processes by RNA-seq analysis of different embryo derivatives from bovine - conceptuses at different developmental stages. Subsequently, the function of some of the genes identified as well as others known to play a crucial role in mouse development or putatively involved in embryo-maternal interactions will be assessed. For - this aim, bovine embryos in which a candidate gene has been ablated (KO) will be generated by CRISPR and transferred to recipient females to assess in vivo the function of such particular gene on conceptus development. A second set of experiments - pursue the development of an in vitro system for conceptus elongation that would bypass the requirement for in vivo experiments. For this aim we will perform metabolomics and proteomics analyses of bovine uterine fluid at different stages and will - use these data to rationally develop a culture system able to sustain conceptus development. The knowledge generated by this project will serve to develop strategies to enhance farming profitability by reducing embryonic loss and to understand - Developmental Biology questions unanswered by the mouse model. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Spain - - - ELONGAN - - - ERC-2017-STG - - - 757886 - - - - - OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN - OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN - - - EUR 1 465 316 - - - CONNECTED CLERICS. BUILDING A UNIVERSAL CHURCH IN THE LATE ANTIQUE WEST (380-604 CE) - - - EUR 1 465 316 - - - Austria - Austria - - - Research Organisations - Research Organisations - - In 380 CE, the Emperor Theodosius (d. 395) ordered all Roman subjects to follow Catholic Christianity and limited imperial patronage to the Catholic Church. Theodosius was the last ruler to reign over a united empire. At his - death the realm was divided into two halves, and by the end of Gregory the Great’s papacy (d. 604), a mosaic of independent kingdoms had replaced the western part of the empire. Yet despite the political division, during this period western clerics - built a supra-regional ecclesiastical structure with substantial levels of hierarchy and cohesion. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Austria - - - CONNEC - - - ERC-2017-STG - - - 757860 - - - - - GOETEBORGS UNIVERSITET - GOETEBORGS UNIVERSITET - - - EUR 1 500 000 - - - Strong Coupling Between Molecules and Vacuum Fields: New Molecular Properties - - - EUR 1 500 000 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Chemistry has had profound impact on society during the last two centuries. From mass production of drugs and pigments, to the invention of plastics, and more recently with the introduction of molecular electronics. However, - some basic physical laws govern possible utilizations. It is therefore of great importance to examine how to bend these laws, how to bypass them and by so doing open up new opportunities for novel applications. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Sweden - - - STRONG - - - ERC-2017-STG - - - 757733 - - - - - THE UNIVERSITY OF MANCHESTER - THE UNIVERSITY OF MANCHESTER - - - EUR 1 494 777 - - - Novel Blueprints for the Visible-Light-Mediated Assembly of C–N Bonds via Nitrogen Radicals - - - EUR 1 494 777 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Nitrogen-containing compounds underpin every aspect of our daily life as they form the structural basis of almost all pharmaceuticals, agrochemicals, food additives and materials. The invention of methods for the formation of - bonds between C and N atoms is of strategic importance for the discovery and evolution of molecules with direct implications on the quality of our lives. Despite this fundamental relevance, forming C–N bonds is still a very challenging task. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - NEBULAR - - - ERC-2017-STG - - - 758427 - - - - - THE HEBREW UNIVERSITY OF JERUSALEM - THE HEBREW UNIVERSITY OF JERUSALEM - - - EUR 150 000 - - - Highly and Widely Effective, Water Stable, and Non Toxic Titanium-Phenolato-based Anticancer Chemotherapy - - - EUR 150 000 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Chemotherapy is the most common line of treatment for various cancer types, but it generally suffers from severe side effects. Cisplatin is a highly effective metallodrug employed in the clinic, limited by severe and - irreversible nephro- and neurotoxicities and resistance development. Therefore, developing highly and widely effective chemotherapy that is non- or substantially less- toxic should impact immediately and significantly the welfare of society. The - titanium metal is an attractive Pt alternative, as it is bio-friendly and non-toxic. Titanium dioxide, the final decomposition product of Ti complexes in water, is a safe material often found in food and cosmetics. Nevertheless, the rapid - dissociation of past Ti complexes in water has hampered their development into drugs. - - 2019-04-30, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Israel - - - safenolaTiCancerDrug - - - ERC-2017-PoC - - - 779689 - - - - - UNIVERSITE LIBRE DE BRUXELLES - UNIVERSITE LIBRE DE BRUXELLES - - - EUR 1 579 213 - - - Quadratic dispersive resonators for optical frequency comb generation - - - EUR 1 579 213 - - - Belgium - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Optical frequency combs are made of thousands of equally spaced spectral lines, each an ultra-stable laser in its own right. They act as “spectral rulers” against which unknown optical frequencies can be measured, and they - have had a revolutionary impact on numerous fields ranging from the detection of extra-solar planets to precision metrology, winning its inventors a Nobel prize in 2005. Traditionally, frequency combs have been generated by ultrashort pulsed lasers, - but in 2007 an important observation changed the research landscape: a continuous-wave laser coupled into a microscopic resonator was shown to spontaneously transform into thousands of comb lines via third-order nonlinear optical effects. I believe - that yet another revolution lies at the horizon. Specifically, recent experiments have alluded to the possibility of realizing optical frequency combs purely through second order (quadratic) nonlinear effects. The intrinsic features of the second - order nonlinearity hold promise to deliver access to new regions of the electro-magnetic spectrum beyond all conventional frequency comb technologies. But unfortunately, experimental investigations are scarce and the physics that underlie frequency - comb formation in quadratic resonators is poorly understood. The goal of the QuadraComb project is to pursue a complete characterization of frequency comb generation in dispersive quadratically nonlinear resonators. I plan to (i) develop theoretical - models to describe quadratic frequency combs, and (ii) develop novel platforms for the experimental realization of quadratic frequency combs. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Belgium - - - QuadraComb - - - ERC-2017-STG - - - 757800 - - - - - UPPSALA UNIVERSITET - UPPSALA UNIVERSITET - - - EUR 1 500 000 - - - SOphisticated 3D cell culture scaffolds for Next Generation Barrier-on-chip In vitro moDels - - - EUR 1 500 000 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The blood-brain barrier is a sophisticated biological barrier comprising several different cell types, structured in a well-defined order with the task to strictly control the passage of molecules - such as drugs against - neurodegenerative diseases - from the blood into the brain. To reduce the ethical and economic costs of drug development, which in EU today uses ~10 million experimental animals every year, we must develop in vitro models of the blood-brain barrier - with high in vivo correlation, as these are completely missing today. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Sweden - - - SONGBIRD - - - ERC-2017-STG - - - 757444 - - - - - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - - - EUR 1 488 674,14 - - - Scaling Methods for Discrete and Continuous Optimization - - - EUR 1 488 674,14 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - One of the most important open questions in optimization is to find a strongly polynomial algorithm for linear programming. The proposed project aims to tackle this problem by combining novel techniques from two different - domains: discrete optimization and continuous optimization. We expect to contribute to exciting recent developments on the interface of these two fields. - - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - ScaleOpt - - - ERC-2017-STG - - - 757481 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 477 500 - - - A Scalable Quantum Network based on Individual Erbium Ions - - - EUR 1 477 500 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - A future quantum network will consist of quantum processors that are connected by quantum channels, just like conventional computers are wired up to form the Internet. In contrast to classical devices, however, the - entanglement and non-local correlations available in a quantum-controlled system facilitate novel fundamental tests of quantum theory and numerous applications in distributed quantum information processing, quantum communication, and precision - measurement. While pioneering experiments have demonstrated the entanglement of two quantum nodes separated by up to 1.3 km, accessing the full potential of quantum networks requires scaling of these prototypes to more nodes and larger distances. To - this end, a new technology that overcomes the bottlenecks of existing physical systems has to be developed. - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - QuantumNet - - - ERC-2017-STG - - - 757772 - - - - - BAR ILAN UNIVERSITY - BAR ILAN UNIVERSITY - - - EUR 1 487 500 - - - New Directions in Lightweight Cryptanalysis - - - EUR 1 487 500 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Over the next five years, fifty billion new smart devices will be connected to the Internet of Things (IoT), creating a revolution in the way we interact with our environment. Such resource constrained devices will require - lightweight cryptography to protect them and us from bad actors. Unfortunately, such schemes can be highly vulnerable: Two notable examples are the encryption schemes used in GSM cellular phones and in car remote controls - both broken by the PI. We - claim that it is not sufficient to adjust the current design and analysis tools to the constrained environment. Instead, we must establish a new research methodology, aiming directly at the problems arising in the 'lightweight realm'. - - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Israel - - - LightCrypt - - - ERC-2017-STG - - - 757731 - - - - - UNIVERSITA DEGLI STUDI DI VERONA - UNIVERSITA DEGLI STUDI DI VERONA - - - EUR 1 233 750 - - - Pre-Classical Anatolian Languages in Contact - - - EUR 1 233 750 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The aim of the PALaC project is to provide a systematic and complete study of language-contact in pre-classical Anatolia, from the XVIII century BCE up the Anatolian and Syro-Anatolian cultures of the Iron ages. Language - contact is a specific phenomenon present in all phases of modern and historical languages, and requires to be investigated using the language-internal methodologies of contact-linguistics. The project will provide a rigorous and complete description - of the linguistic interactions in ancient Anatolia, a unique historical and geographical gateway where Indo-European, Semitic and isolated languages interacted with each other, on the ideal boundary between the East and the West. PALaC will deal with - the analysis of the textual data from the different Ancient Anatolian corpora, that will be assessed both from a linguistic and from philological perspective. The final results will also be integrated in the general framework of historical and - cultural contact in the Ancient Mediterranean world by a dedicated work-package. The project will take advantage of the methodological expertise of a team of researchers who are well trained both in the philological study of the Ancient Near Eastern - texts and in the linguistic study of languages in contact. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Italy - - - PALaC - - - ERC-2017-STG - - - 757299 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 144 549 - - - Optical NanoActuators for Nanomachines and Microfluidic Chips - - - EUR 144 549 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Over the past 2 years we have developed and patented a new actuator which is based on composite polymer/metal nanoparticles. Originally designed to create strong reversible colour changes, we found that the forces generated in - the actuation exceed current microscale devices by nearly two orders of magnitude (weight for weight). We have thus protected and developed this possibility using my Advanced ERC project, LINASS, together with Cambridge Enterprise (CE, the - commercialisation arm of the University of Cambridge). We have now reached the stage where we believe that this can become commercially interesting, have progressed to a better understanding of the fundamental processes, and have some idea of the - applications that it might enable. The PoC project here is thus conceived to create demonstrators in two related domains: one offers new possibilities in advancing the established technology of microfluidic chips, while the other opens up a new space - entirely, by making DNA nano-machines active and feasibly exploitable. - - 2019-06-30, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - ANTNAM - - - ERC-2017-PoC - - - 778616 - - - - - TECHNISCHE UNIVERSITAET GRAZ - - - EUR 166 156,80 - - - Magnetic Enzyme Metal Organic Framework Composites - - - EUR 166 156,80 - - - Austria - - - Higher or Secondary Education Establishments - - The aim of this interdisciplinary project is to develop composites consisting of metal-organic frameworks (MOFs), magnetic nanoparticles (MNPs), and enzymes. The MOF coating protects the biomacromolecule from inhospitable - conditions, and provides a permeable and selective molecular gate for the diffusion of substrates and products, thanks to its intrinsic and tunable porosity. External magnetic forces acts on the MNPs to allow for precise positioning of this ternary - system. - - - 2019-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Austria - - - MNEMONIC - - - H2020-MSCA-IF-2016 - - - 748649 - - - - - HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH - HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH - - - EUR 1 499 938 - - - Astrocyte-Neuronal Crosstalk in Obesity and Diabetes - - - EUR 1 499 938 - - - Germany - Germany - - - Research Organisations - Research Organisations - - Despite considerable efforts aimed at prevention and treatment, the prevalence of obesity and type 2 diabetes has increased at an alarming rate worldwide over recent decades. Given the urgent need to develop safe and efficient - anti-obesity drugs, the scientific community has to intensify efforts to better understand the mechanisms involved in the pathogenesis of obesity. Based on human genome-wide association studies and targeted mouse mutagenesis models, it has recently - emerged that the brain controls most aspects of systemic metabolism and that obesity may be a brain disease. I have recently shown that like neurons, astrocytes also respond to circulating nutrients, and they cooperate with neurons to efficiently - regulate energy metabolism. So far, the study of brain circuits controlling energy balance has focused on neurons, ignoring the presence and role of astrocytes. Importantly, our studies were the first to describe that exposure to a high-fat, - highsugar (HFHS) diet triggers hypothalamic astrogliosis prior to significant body weight gain, indicating a potentially important role in promoting obesity. Overall, my recent findings suggest a novel model in which astrocytes are actively involved - in the central nervous system (CNS) control of metabolism, likely including active crosstalk between astrocytes and neurons. To test this hypothetical model, I propose to develop a functional understanding of astroglia-neuronal communication in the - CNS control of metabolism focusing on: 1) dissecting the ability of astrocytes to release gliotransmitters to neurons, 2) assessing how astrocytes respond to neuronal activity, and 3) determining if HFHS-induced astrogliosis interrupts this crosstalk - and contributes to the development of obesity and type 2 diabetes. These studies aim to uncover the molecular underpinnings of astrocyte-neuron inputs regulating metabolism in health and disease so as to inspire and enable novel therapeutic - strategies to fight diabetes and obesity. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - AstroNeuroCrosstalk - - - ERC-2017-STG - - - 757393 - - - - - THE UNIVERSITY OF BIRMINGHAM - THE UNIVERSITY OF BIRMINGHAM - - - EUR 1 481 183,75 - - - A Framework for Metaphysical Explanation in Physics - - - EUR 1 481 183,75 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - There is a growing consensus that causal explanation is not the whole story about explanation in science. Metaphysics has seen intense recent attention to the notion of grounding; in philosophy of physics, the focus has been - on mathematical and structural explanation. But the grounding debate has been criticized for insularity and disconnection from scientific practice, while work on explanation in physics tends to overlook the sophisticated logical systems and - conceptual distinctions developed in metaphysics. This situation hinders understanding of novel explanatory scenarios n philosophy of physics, where familiar models of causal explanation seem to break down. FraMEPhys addresses these challenges by - combining new conceptual innovations and insights from both metaphysics and philosophy of physics to transform our understanding of the nature of explanation. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - FraMEPhys - - - ERC-2017-STG - - - 757295 - - - - - HELSINGIN YLIOPISTO - HELSINGIN YLIOPISTO - - - EUR 1 499 905 - - - voCAL articuLations Of Parliamentary Identity and Empire - - - EUR 1 499 905 - - - Finland - Finland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - What did politicians sound like before they were on the radio and television? The fascination with politicians’ vocal characteristics and quirks is often connected to the rise of audio-visual media. But in the age of the - printed press, political representatives also had to ‘speak well’ – without recourse to amplification. - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Finland - - - CALLIOPE - - - ERC-2017-STG - - - 757291 - - - - - GOLDSMITHS' COLLEGE - GOLDSMITHS' COLLEGE - - - EUR 150 000 - - - Citizen Sense Air Monitoring Kit - - - EUR 150 000 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In January 2013, the five-year ERC funded project Citizen Sense was launched, investigating the role of low-cost and digital monitoring technologies in facilitating and organising new types of environmental engagement. This - proposal brings together a comprehensive citizen-sensing toolkit for users to undertake air quality monitoring that realises the social and environmental potential of these technologies. With the benefit of five years of intensive and cutting-edge - research, the Citizen Sense research project is exceptionally well positioned to develop an AirKit, thereby bridging the gap between our research and the early stages of innovation in order to realise the innovation potential of the project. Our - research pioneers new strategies of citizen-led monitoring and data analysis that join up hardware and software developments along with social innovations in order to produce an AirKit toolkit that has the potential to revolutionise community - monitoring infrastructures and practices. This PoC will help to establish the viability of the AirKit, to refine and address technical issues, and to consolidate the overall direction of the AirKit. - - 2019-12-31, Grant Agreement signed - - - 2018-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - AirKit - - - ERC-2017-PoC - - - 779921 - - - - - UNIVERSITA CA' FOSCARI VENEZIA - UNIVERSITA CA' FOSCARI VENEZIA - FONDAZIONE CENTRO EURO-MEDITERRANEO SUI CAMBIAMENTI CLIMATICI - - - EUR 1 495 000 - - - ENERGY use for Adaptation - - - EUR 1 495 000 - - - Italy - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - ENERGYA will improve our understanding of how energy and energy services can be used by households and industries to adapt to the risk posed by climate change. Specifically, the project will develop an interdisciplinary and - scalable research framework integrating data and methods from economics with geography, climate science, and integrated assessment modelling to provide new knowledge concerning heterogeneity in energy use across countries, sectors, socioeconomic - conditions and income groups, and assess the broad implications adaptation-driven energy use can have on the economy, the environment, and welfare. - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Italy - - - ENERGYA - - - ERC-2017-STG - - - 756194 - - - - - BAR ILAN UNIVERSITY - BAR ILAN UNIVERSITY - - - EUR 1 372 839 - - - CRISPR Gene Correction for Severe Combined Immunodeficiency Caused by Mutations in Recombination-activating gene 1 and 2 (RAG1 and RAG2) - - - EUR 1 372 839 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The severe combined immunodeficiencies (SCIDs) are a set of life threatening genetic diseases in which patients are born with mutations in single genes and are unable to develop functional immune systems. While allogeneic bone - marrow transplantation can be curative for these diseases, there remain significant limitations to this approach. Gene therapy using viral vectors containing a corrective transgene is being developed for some of these disorders, most successfully for - ADA-SCID. However, for other SCID disorders, such as those caused by genetic mutations in RAG1 and RAG2, the transgene needs to be expressed in a precise, developmental and lineage specific manner to achieve functional gene correction and to avoid - the risks of cellular transformation. In contrast to using viral vectors to deliver transgenes in an uncontrolled fashion, we are working towards using genome editing by homologous recombination (HR) to correct the disease causing mutation by - precisely modifying the genome. We have shown that by using clustered, regularly interspaced, short palindromic repeats (CRISPR) and the CRISPR-associated protein 9 (Cas9) system we can stimulate genome editing by HR at frequencies that should be - therapeutically beneficial (>10%) in hematopoietic stem and progenitor cells (HSPCs). The overall focus of the proposal is to translate our basic science studies to use in RAG-SCID patient-derived HSPCs in methodical, careful and pre-clinically - relevant fashion. The fundamental approach is to develop a highly active functional genome editing system using CRISPR-Cas9 for RAG-SCIDs and complete pre-clinical efficacy and safety studies to show the approach has a clear path towards future - clinical trials. Our goal with this proposal is to develop the next wave of curative therapies for SCIDs and other hematopoietic disorders using genome editing. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Israel - - - CRISS - - - ERC-2017-STG - - - 755758 - - - - - KATHOLIEKE UNIVERSITEIT LEUVEN - KATHOLIEKE UNIVERSITEIT LEUVEN - - - EUR 1 947 519 - - - Nanomaterials in Oncology: Exploiting the Intrinsic Cancer-Specific Toxicity of Nanoparticles. - - - EUR 1 947 519 - - - Belgium - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In our current society, therapeutic strategies against cancer suffer from dose-limiting toxicity, lack of specificity and high morbidity. To overcome this, the use of nanomaterials (NMs) is rising, where several NM - formulations are undergoing clinical trials or are used in clinics where the NMs are used as drug delivery vehicles or as mediators in physical anticancer methods (e.g. hyperthermia), where to date, the success rate is limited due to low tumor - targeting efficacy, lack of specificity and frequent re-use of classical toxicity mechanisms. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Belgium - - - NANONC - - - ERC-2017-STG - - - 757398 - - - - - UNIVERSITAETSKLINIKUM FREIBURG - UNIVERSITAETSKLINIKUM FREIBURG - - - EUR 149 937 - - - Magnetic Resonance Shimming Applications with Near-magnet Equipment - - - EUR 149 937 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Magnetic resonance (MR) imaging and spectroscopy critically relies on the homogeneity of the main field. Despite of the best technological efforts magnetic field in MR examinations cannot be made homogeneous due to the - presence of the object of investigation – the human or an animal – in the magnet. Heterogeneous and unique distribution of tissues with their characteristic magnetic susceptibilities requires the process of field homogenization, termed shimming, to - be performed on a subject-by-subject basis. Shimming subsystems of the clinical MRI devices often show insufficient, leading to sub-optimal image quality and even failing diagnosis. Furthermore, numerous emerging methods, while showing their great - potential in research settings, require even better shim fidelity. We therefore identify improved shimming as a current unmet need in MRI. Add-on hardware for more reliable shimming will greatly aid MRI research especially in the field of ultra-high - imaging, such as 7T and above. A wider availability of improved shimming capabilities in the clinical machines will accelerate the transition of a multitude of current promising scientific applications of MRI to the clinical practise, allowing for a - more precise diagnosis and improved patient outcomes. - - - 2019-03-31, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Germany - - - mrSANE - - - ERC-2016-PoC - - - 755466 - - - - - BAR ILAN UNIVERSITY - BAR ILAN UNIVERSITY - - - EUR 149 566 - - - Voltage Nanosensors for Applications in Neuroscience - - - EUR 149 566 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - To understand how the brain works, tools need to be developed to allow the investigation of interactions between individual neurons. Towards this goal, We developed voltage sensing nanoparticles (vsNPs) in the shape of - nanorods (vsNRs) that self-insert into the cell membrane and could optically record, non-invasively, action potentials (APs) at the single-particle and nanoscale level, at multiple sites, in a large field-of-view. The proposed nanosensors have unique - advantages not offered by other methods: much larger voltage sensitivity, high brightness, and hence single-particle voltage sensitivity, large spectral shift , fast temporal response, minimal photobleaching, large two-photon excitation cross - sections, excellent performance in the NIR, and compatibility with lifetime imaging. - - 2019-04-30, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Israel - - - NiSAN - - - ERC-2017-PoC - - - 779896 - - - - - INSTITUT DES HAUTES ETUDES SCIENTIFIQUES - INSTITUT DES HAUTES ETUDES SCIENTIFIQUES - - - EUR 1 499 912 - - - Critical behavior of lattice models - - - EUR 1 499 912 - - - France - France - - - Research Organisations - Research Organisations - - Statistical physics is a theory allowing the derivation of the statistical behavior of macroscopic systems from the description of the interactions of their microscopic constituents. For more than a century, lattice models - (i.e. random systems defined on lattices) have been introduced as discrete models describing the phase transition for a large variety of phenomena, ranging from ferroelectrics to lattice gas. - - 2023-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - CriBLaM - - - ERC-2017-STG - - - 757296 - - - - - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - CONSORZIO INTERUNIVERSITARIO PER LO SVILUPPO DEI SISTEMI A GRANDE INTERFASE - EPISTIMONIKO PARKO PATRON AE - - - EUR 149 875 - - - Graphene as effective anti-fading agent for the protection of artworks - - - EUR 149 875 - - - Greece - Greece - Italy - Greece - - - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - All art materials are prone to degradation; in particular, the introduction of new creative manufacturing techniques in the 20th century art has yielded artworks with short lifetime expectancy. Fading, yellowing and - discolouration are the most common degradation effects that result from the exposition to UV and visible light and oxidizing agents. The result of the degradation is the irreversible alteration of the appearance of contemporary artworks, which is a - patrimony of mankind. This PoC project aims to develop innovative, multi-functional graphene-based products (graphene ‘veils’ and inclusions) that provide UV shielding, de-acidification, oxygen and humidity barriers for the protection of old and - modern paintings and artworks. Recent advances in the understanding of the mechanical integrity of large graphene membranes as well as of innovative graphene-transfer processes through the current ERC Tailor Graphene has made possible the emergence - of this application of strong societal value. The transparent protective graphene veil can be easily removed so it does not constitute an irreversible intervention on the art object. Moreover, for such an application the price of graphene does not - hamper its business potential since the quantities are minimal. Two different classes of products are envisaged; CVD graphene membranes directly deposited to artworks for which transparency is required and graphene flakes that will be dispersed to - colour paints and varnishes so as to bestow enhanced UV, oxidation and humidity resistance. The latter paves the way to extend this application to the huge market of architectural paints. A multi-disciplinary approach will be pursued for the - implementation of this PoC and involves experimentation with CVD graphene sheets of various morphologies and sizes and the dispersion of nanographene as additives in paints. Finally, the development of a Business Plan will be undertaken in - collaboration with business developers and patent specialists. - - 2019-03-31, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Greece - - - GRAPHENART - - - ERC-2017-PoC - - - 779985 - - - - - ISTITUTO NAZIONALE DI FISICA NUCLEARE - - - EUR 3 186 000 - - - FELLowship for Innovation at INFN - - - EUR 6 372 000 - - - Italy - - - Research Organisations - - The FELLINI fellowship programme is a new, high-quality fellowship scheme based on a modern research and training approach, which aims at research excellence and promoting researcher mobility and training. FELLINI combine best - practice found across the EU with a number of innovative elements that shall provide all Fellows with an ideal basis for their future careers, preparing them for a wide range of career options. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2016 - Co-funding of regional, national and international programmes - - - MSCA-COFUND-FP - Fellowship programmes - - - Italy - - - FELLINI - - - H2020-MSCA-COFUND-2016 - - - 754496 - - - - - UNIVERSITAT DE BARCELONA - - - EUR 158 121,60 - - - Remembering the Sound of Images: Cross-cultural study of rock art soundscapes and knowledge transmission in the New and Old Worlds. - - - EUR 158 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - How do societies remember? Memory is fragile and volatile and thus people around the world, and through time, have created ways to recall events and to share knowledge. - - - 2020-01-14, ongoing project - - - 2018-01-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - MEMORISING - - - H2020-MSCA-IF-2016 - - - 750706 - - - - - FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION - - - EUR 175 419,60 - - - Functional exploration of the contributions of brainstem-motor thalamic pathways to motor execution and learning - - - EUR 175 419,60 - - - Switzerland - - - Research Organisations - - Motor learning is a fundamental process enabling an organism to improve movement efficiency during a motor task. It is supported by motor cortex, which organizes movements into complex sequences. Yet, how this structure is - informed of planned and generated actions is poorly understood. Anatomically, motor cortex is highly interconnected with the motor thalamus (Mthal). Interestingly, this structure is involved during the acquisition of different motor tasks, but also - shows homologous roles in motor function to brainstem areas. In line with these observations, we hypothesize that pathways between the brainstem to Mthal represent an interesting and unexplored way for motor information to reach cortical areas during - motor learning. - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - MoThal - - - H2020-MSCA-IF-2016 - - - 749527 - - - - - THE UNIVERSITY OF NOTTINGHAM - THE UNIVERSITY OF NOTTINGHAM - - - EUR 149 912 - - - Electrocatalytic Nanoreactors for Absorption, Detection and Decontamination of Hazardous Compounds - - - EUR 149 912 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Chemical warfare agents (CWA) are one of the most odious weapons of mass destruction, designed to incapacitate humans by causing blistering, choking, internal bleeding and vomiting on a grand scale. CWA are inexpensive and - relatively easy to synthesise making them accessible to terrorist groups, providing a means for the administration of large scale damage with only small quantities of materials. Current state-of-the-art methods to detect or decontaminate CWA lack - efficiency and flexibility and, with tensions in numerous war zones pushed to breaking point. By building on the fundamental scientific discoveries made in the ERC Consolidator grant (No 277784, NANOMOL), we shall extend and develop the application - of electrochemically active carbon nanoreactors for the detection and decontamination of CWA, such as mustard gas and other agents. The nanoscale electrochemical platform (NANOELECTROCHEM) developed in this Proof of Concept (PoC) project is expected - to be universally applicable for the triple-use (absorption + detection + decontamination) of a wide spectrum of CWA and many other harmful anthropogenic compounds, within the single platform allowing for an extremely portable device for a range of - practical applications. - - 2019-05-31, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - NANOELECTROCHEM - - - ERC-2016-PoC - - - 754682 - - - - - WEIZMANN INSTITUTE OF SCIENCE - WEIZMANN INSTITUTE OF SCIENCE - - - EUR 1 490 596 - - - The Ocean's Oxygen Isotopes Deciphered: Combining Observations, Experiments and Models - - - EUR 1 490 596 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The isotopic composition of O in seawater is a fundamental property of Earth's oceans, key to paleoclimate reconstructions and to our understanding of the origin of water on Earth, the water-rock reactions that govern seawater - chemistry, and the conditions under which life emerged. Despite more than five decades of research, the geologic history of seawater 18O/16O remains a topic of intense debate. Without exception, well-preserved 18O/16O records from marine precipitates - reflect both the minerals' formation temperature, and the isotopic composition of seawater. This duality has prevented unique interpretation of a long-term secular trend, in which 18O/16O in sedimentary rocks (e.g., carbonates, cherts) has increased - by ~15 ‰ since the Archean. Here I outline an inter-disciplinary research program to address this fundamental problem, which integrates new geochemical observations, laboratory experiments, and numerical models. - - 2023-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Israel - - - OOID - - - ERC-2017-STG - - - 755053 - - - - - TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY - TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY - - - EUR 1 432 730 - - - New horizons in homogeneous dynamics and its applications - - - EUR 1 432 730 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - We present a large variety of novel lines of research in Homogeneous Dynamics with emphasis on the dynamics of the diagonal group. Both new and classical applications are suggested, most notably to: - - - 2023-09-30, Grant Agreement signed - - - 2018-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Israel - - - HD-App - - - ERC-2017-STG - - - 754475 - - - - - FUNDACION IMDEA NANOCIENCIA - - - EUR 170 121,60 - - - 2D magnetic materials for molecular SPINtronics - - - EUR 170 121,60 - - - Spain - - - Research Organisations - - Spintronics, which aims at using the spin state of electrons to process information, is a promising route to supplement conventional electronics. The field is rapidly diversifying into Molecular Spintronics where magnetic - molecules are the core of the devices and Organic Spintronics where spin currents are injected from ferromagnetic metals into organic materials like graphene. The electrical control of the molecular magnetism and the spin injection are however still - limited and not well understood. In my proposal 2DSPIN, I propose to push Spintronics beyond the state-of-the-art by merging new magnetic 2D materials (Fe0.25TaS2) with magnetic molecules (0D) in hybrid mixed-dimensional (0D-2D) devices. I aim to - achieve a full control over the spin of individual molecules by injecting spin polarized currents from all-2D devices. The electrical addressing of the spin of magnetic molecules with spin polarized currents is expected to open a new route to address - and switch the molecular spin. As a proof-of-concept of this control, my proposal aims at fabricating spin filters based on individual organic radicals linked to Fe0.25TaS2 electrodes. Along the road, I expect to achieve enhanced and robust spin - injection in non-magnetic materials, like graphene, and a controlled tuning of molecular magnetic properties through the interaction with magnetic layered materials in van der Waals heterostructures. The use of intrinsically magnetic 2D materials - will overcome present limitations set by technological difficulties like the oxidation, the low spin polarization of traditional ferromagnetic metals and the dimensionality mismatch between molecules and electrodes. - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - 2DSPIN - - - H2020-MSCA-IF-2016 - - - 746579 - - - - - UNIVERSITAT KONSTANZ - - - EUR 171 460,80 - - - Development of novel computational biology pipeline for the efficient classification of titin SNPs for clinical use - - - EUR 171 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - Mutations in the giant muscle protein titin are a major cause of heart disorders in human populations. Routine DNA screening of patient cohorts is now becoming feasible, with a staggering number of titin truncations and - missense single nucleotide polymorphisms (mSNPs) rapidly accumulating in genomics databases (>17,000 mSNPs). While the link between titin truncation and disease is now becoming clarified, detecting the pathogenic potential of mSNPs remains a - substantial challenge. In mSNPs classification, bioinformatics evaluation is a necessary first filtering step, but existing predictors are poorly reliable. To address this problem, we aim to develop a new titin-centric scoring function that predicts - the mechanistic effect of an mSNP exchange in the titin protein by considering the specific characteristics of its poly-domain chain. For this work, we will build a medium-throughput molecular diagnostic pipeline that harvest existent structural - models of titin components in estimating mSNPs-induced changes in free energy and conformational dynamics in the protein. Calculations will be benchmarked against experimentally obtained biophysical and biochemical data. To develop this methodology, - we will use a clinically pertinent training set of 75 mSNPs. However, in a subsequent step, stable predictions will be extrapolated to the rest of the titin chain by exploiting the repetition of structural and functional loci within the chain. A - titin map of vulnerability “hot-spots” so calculated will be distributed to the research community. Ultimately, we aim to produce a tool that can aid clinicians to identify patients at risk of developing a titin-based heart condition at early disease - stages, where intervention is still possible. - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - TTNPred - - - H2020-MSCA-IF-2016 - - - 753054 - - - - - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - - - EUR 183 454,80 - - - Photovoltaic Control and Integration - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - According to the "Europe 202 strategy", Europe should increase the use of photovoltaics (PV) and other renewable energy sources (RES) for a sustainable future. However, to this day, PV plants are not-controllable power - sources, thus imposing limits on PV penetration due to technical restrictions. - - 2019-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - PVCI - - - H2020-MSCA-IF-2016 - - - 746638 - - - - - UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN - - - EUR 187 866 - - - The Gendered Politics of Emotion in Austerity Ireland - - - EUR 187 866 - - - Ireland - - - Higher or Secondary Education Establishments - - This research project surveys and theorises the politics of shame in the contemporary Irish context. It identifies the deployment and manipulation of emotions in public discourses, particularly with regard to historically - marginalised groups, since the onset of the economic crisis, and teases out the gendered and classed operation of the politics of shame. The project establishes the role shame plays in the contemporary political setting post-2008 with the - introduction of austerity as a policy-response to the economic crisis. Building on theoretical work highlighting the increased shame-proneness of traditionally disadvantaged groups, the project examines the linkage between gender and shame. Although - shame has been understood to be entangled with patriarchal norms concerning women’s bodies and sexuality it has, so far, not been theorised with regard to gender and material disadvantage and poverty. There is some empirical evidence that shame, - does, in fact, manifest itself in impoverished populations, and that this may be amplified or at least complicated by gender. The project forms the first political theoretical treatment of the economic crisis and the policy-response to same, and - focuses, uniquely, on gender and class. It will does so, again uniquely, through a framing in terms of affect and the politics of emotion. The project seeks to capture just how those experiencing austerity most immediately, conceptualise their - disproportionate disadvantaging, and whether they themselves engage a politics of shame. The training and career development provisions of the project aim to enhance the researcher's profile as a specialist in gender, who is equally adept at engaging - social science and humanities research methods, and facilitate a deeper probing of a complex empirical context as it relates to gender, shame, and economic disadvantage. - - 2019-11-12, ongoing project - - - 2017-11-13 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Ireland - - - GENDEMOTION - - - H2020-MSCA-IF-2016 - - - 750326 - - - - - UNIVERSITE DE FRIBOURG - - - EUR 187 419,60 - - - Identification and characterization of sites of lipid droplet biogenesis in the ER - - - EUR 187 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - Lipid droplets (LDs) are evolutionarily conserved dynamic organelles dedicated to storage of fat. Relatively little is known about the molecular processes that regulate nascent LD formation at specific sites in the endoplasmic - reticulum (ER). Understanding LD biogenesis and degradation is crucial for deciphering the pathophysiology of LD storage disorders, like obesity, diabetes type-2, atherosclerosis, and lipodystrophy. The main objective of this project is to precisely - map and characterize LD biogenesis sites in the ER using the model eukaryote, S. cerevisiae. One reason so little is known about the earliest stages of LD biogenesis is that until recently we have not had tools to visualize and characterize these - sites. However, I have generated a yeast strain in which it is possible to use electron microscopy to image the earliest stages of LD biogenesis. In a recently published study I used this strain to characterize early stages of LD biogenesis and I - propose to use this strain to investigate the role of a number of proteins in LD biogenesis by using mutants lacking these proteins. In addition, I have developed the first fluorescent protein marker of sites of nascent LD biogenesis. This new - protein will allow me to use fluorescent microscopy to visualize LD biogenesis in live cells and in mutants lacking proteins known to be involved in LD biogenesis. I will also use this protein as a molecular tool to identify proteins and lipids that - are enriched at LD biogenesis sites in the ER by performing immuno-purification and mass-spec analyses. The proposed studies will reveal and identify proteins and lipids necessary for the earliest stages of LD biogenesis and will make possible future - mechanistic studies of LD biogenesis. My participation in “LD_biogenesis” will broaden my scientific expertise and hone my competences in becoming a successful project investigator. - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Switzerland - - - LD_Biogenesis - - - H2020-MSCA-IF-2016 - - - 747536 - - - - - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - - - EUR 171 460,80 - - - Light triggered non-invasive gene delivery through lipopolyplexes - - - EUR 171 460,80 - - - Germany - - - Research Organisations - - Target-specific and controlled drug delivery are nowadays integral and extremely promising parts of research and practice in modern medicine. It gives an option to reduce drug toxicity and increase bioavailability by - delivering a drug to a specific site with defined concentration. During the last decade highly efficient non-viral gene delivery has been achieved by encapsulation of nucleic acids into complexes of liposomes and polycations - lipopolyplexes (LPP) - - new generation gene delivery systems. The main challenge in liposome-based gene delivery is to achieve high level of control over gene release. The main aim of this project is to develop a new approach for non-invasive gene delivery while gene - release is highly controlled in space and time. This will be achieved by the design of infra-red light sensitive LPPs. The project includes engineering of the tailor-made LPPs, detailed investigation of the light triggered release mechanism, and will - eventually result in intracellular light triggered gene delivery. Expert knowledge of the researcher together with the knowledge to be contributed by the hosting institution and from collaborations established by the researcher worldwide will allow - successful project implementation. Mutual knowledge transfer will strengthen scientific contacts within and outside the EU as well as will let the researcher to develop her own independent research career. Attraction of interest from industrial - partners is expected in case of success. Collaboration with industrial partners will profit from an exceptional record of the host with successful industrial projects. - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - LIGHTOPLEX - - - H2020-MSCA-IF-2016 - - - 747245 - - - - - THE UNIVERSITY OF NOTTINGHAM - - - EUR 183 454,80 - - - Hopfield neural network dynamics in open quantum systems - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Understanding how quantum effects can improve the performance of actual computing devices is an exciting and growing research area. However their role in neural networks (NNs), the complementary information process paradigm of - classical computation is largely unexplored. The full translation of this paradigm at the quantum level ultimately requires to combine disordered spin-systems techniques, widely used in the study of classical NNs, together with the open quantum - systems (OQSs) framework, in order to achieve their irreversible and non-linear dynamics. HopeQNet is the first step of an ambitious program that will lead, in a long term effort, to a new generation of quantum computing architectures, and is - designed to deliver a first initial theoretical framework to investigate quantum effects in NNs, by considering the open quantum generalization of one of the most celebrated paradigms of NNs, the Hopfield model. This workhorse model will be simple - and rich enough to: (i) apply well-developed tools from the theory of OQSs and establish a meaningful framework for a quantum NN; (ii) evaluate the potential gain due to quantum effects in this specific quantum NN architecture; (iii) engineering and - modeling a proof-of-principle experiment of a Rydberg quantum simulator implementing it. - - - 2019-11-02, ongoing project - - - 2017-11-03 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - HopeQNet - - - H2020-MSCA-IF-2016 - - - 746442 - - - - - ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE - - - EUR 183 454,80 - - - Constructing a theory of phonotactic processing during speaking - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Languages of the world have their unique ways of putting sounds together. For example, word-initial /ŋ/ sounds bizarre to an English but not to a Cantonese speaker’s ear (e.g. /ŋoi/ “love”). These constraints on where sounds - tend to occur and how they are typically sequenced within a word are called “phonotactic”. Phonotactic constraints are a source of significant regularity in the sound system of any language. How do humans exploit this phonotactic regularity when they - produce speech? This project will provide a general and yet unprecedented theoretical framework of how this happens in a variety of communicative situations. We will develop three converging approaches in order to achieve this goal. First, we will - bring together insights from linguistic theory and computational linguistics to develop a comprehensive characterization of phonotactic dependencies in English. Second, we will investigate how phonotactic information is represented in the human mind - and how it is used in speaking. To achieve this, we will generate concrete predictions using cognitive psychological models of speech production and reading aloud, thus bridging the gap between these two fields of scientific enquiry that have been - long treated as independent. We will simultaneously exploit tools and tasks from cognitive psychology and experimental phonetics to test our predictions empirically through behavioural experimentation. Finally, we will capitalise on advances in the - science of learning, to determine phonotactic dependencies shape the acquisition of literacy. This research will shed light on mechanisms involved in the processing of sounds during reading, speaking, and the acquisition of these skills, and will - inform the development of novel methods for teaching and enhancing literacy in first and second language. - - 2020-09-30, Grant Agreement signed - - - 2018-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - PhonPred - - - H2020-MSCA-IF-2016 - - - 747987 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 149 875 - - - Graphene-based High Resolution Neural Interfaces for ICT-inspired Neuro-treatment - - - EUR 149 875 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Electronic devices enabling communication with human nervous system are becoming increasingly prevalent, offering novel information and communication (ICT)-based treatment techniques to help people overcome various disorders - ranging from spinal cord injuries (SCIs) to missing limbs. Millions of people worldwide suffer from such ailments with a cumulative cost to the society estimated in billions of Euros annually. Next-generation ICT-based treatment techniques demand for - interfaces with higher spatial resolution compared to state-of-the-art. To address this demand, MINERGRACE aims to build a prototype transceiver with high spatial resolution based on nano-patterned graphene sheets (NPGSs), which can be utilised as - high resolution neural interfaces (NIs) capable of differentiating and generating highly localised fluctuations in specific ion concentrations. As the project outcome, MINERGRACE will provide a proof-of-concept NPGS-based NI prototype, i.e., a - portable electronic device that can be integrated with a microprocessor. High resolution aspects of the MINERGRACE project outcome will provide a very significant improvement to the state-of-the-art in terms of both the capacity of the communication - and the complexity of data communicated with the nervous system, enabling the communication with individual neurons. The project outcome will have a wide spectrum of applications involving NIs, e.g., ICT-based SCI treatments and neuro-prosthesis, - significantly contributing to their quality of service. Commercialisation process will involve investigation into other commercialisation activities towards other NI products, development of an understanding of intellectual property rights (IPR) - positions, and strategies for patenting activities in light of the achieved understanding of IPR position. We will work with identified industrial partners and societal organisations to collaborate towards in-market positioning for delivering the - product to potential end users. - - 2019-07-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - MINERGRACE - - - ERC-2017-PoC - - - 780645 - - - - - UNIVERSITAETSKLINIKUM FREIBURG - UNIVERSITAETSKLINIKUM FREIBURG - - - EUR 149 900 - - - Disseminating N-terminomics to Advance Protease Research - - - EUR 149 900 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Protein N-termini represent a wealth of biological information, such as their generation by limited proteolysis, which sculpts proteome functionality by yielding protein-sized cleavage products with novel functionality. - N-terminomics is a branch of functional proteomics and enables the analysis of thousands of protein N-termini in an unbiased manner. By targeting native, proteolytically generated or acetylated protein N-termini as well as uncovering novel - translation initiation sites, N-terminomics bears relevance to proteolysis and proteogenomics research. Unlike proteomic assays to study modifications such as phosphorylation, N-terminomics has remained inaccessible to non-expert laboratories due to - a lack of ready-to-use kit formats or commercial services. Based on a recently published N-terminomic workflow by my laboratory, the present project aims to fill this niche by laying the foundation to represent N-terminomics (sample preparation up to - mass spectrometry analysis) in a kit-like format together with online data analysis. Development steps include inclusion of multiple internal standards for improved sample-to-sample comparability, sole usage of cost-effective, disposable - “small-scale” equipment in sample preparation, minimization of required input material, adaption to different input material including cryopreserved and formalin-fixed, paraffin-embedded samples, as well as web-based mass spectrometry data analysis - and annotation. This endeavor is based on multiple collaborative projects of the applicant with pharmaceutical companies and backed by interest of proteomic supply companies. In a small forward-looking activity, the project will explore the - application N-terminomics in molecular diagnostics of bladder cancer; based on the rationale local infiltration by solid tumors is based on differential proteolysis. This activity serves an initial step to add N-terminomics to the toolbox of - molecular pathology. - - 2019-06-30, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Germany - - - ProteaseNter - - - ERC-2017-PoC - - - 780730 - - - - - UNIVERSITY OF LEEDS - - - EUR 183 454,80 - - - Glycoprotein-based inhibitors of shiga-like toxin - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Gastrointestinal infections have substantial impact in both the developing world and in Europe with 1.5 billion cases each year leading to approximately two million deaths each year, 760,000 of which are in children under five - years old. Many of these deaths are caused by bacteria for example E. coli O157, that produces protein toxins, including shiga-like toxin (SLT). In the human body, the surfaces of living cells are covered in complex carbohydrate molecules. This - “sugar coating” allows the cells to interact with viruses, bacteria, and toxins that have complementary protein receptors. The pentagonal shiga-like toxin produced by E. coli O157 bacteria can attach to five copies of a specific carbohydrate on the - gut wall and enter cells lining the intestine. The result is bloody diarrhoea and the toxin entering the circulatory system to cause kidney failure. - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - GlypStx - - - H2020-MSCA-IF-2016 - - - 746421 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 450 000 - - - Probabilistic Automated Numerical Analysis in Machine learning and Artificial intelligence - - - EUR 1 450 000 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Numerical tasks - integration, linear algebra, optimization, the solution of differential equations - form the computational basis of machine intelligence. Currently, human designers pick methods for these tasks from - toolboxes. The generic algorithms assembled in such collections tend to be inefficient on any specific task, and can be unsafe when used incorrectly on problems they were not designed for. Research in numerical methods thus carries carries the - potential for groundbreaking advancements in the performance and quality of AI. - - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - PANAMA - - - ERC-2017-STG - - - 757275 - - - - - DEUTSCHES INSTITUT FUR WIRTSCHAFTSFORSCHUNG DIW (INSTITUT FUR KONJUNKTURFORSCHUNG) EV - - - EUR 171 460,80 - - - Paternity leave and the gender gap in pay and earnings - - - EUR 171 460,80 - - - Germany - - - Research Organisations - - This project will estimate the impact of the gender split in parental leave on gender gaps in labour market outcomes and domestic work. I will address this topic, which is of Europe-wide policy relevance, by examining the - parental leave policy in Germany. To provide causal estimates, I will make use of variation in the gender split in leave that is due to a cap in the income-related benefit payments at 1,800€ per month. A preliminary step for the analysis, is to - confirm empirically that the cap in parental leave benefits does in fact induce variation in the gender split of leave. Following on from this, the main analysis will make use of differences in the gender split in leave that result specifically from - the benefit cap in order to answer two questions: - - 2020-02-29, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - PAGE - - - H2020-MSCA-IF-2016 - - - 752053 - - - - - UNIVERSITY COLLEGE LONDON - UNIVERSITY COLLEGE LONDON - UNIVERSITY OF BRIGHTON - - - EUR 2 243 584 - - - Ecological Language: A multimodal approach to language and the brain - - - EUR 2 243 584 - - - United Kingdom - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The human brain has evolved the ability to support communication in complex and dynamic environments. In such environments, language is learned, and mostly used in face-to-face contexts in which processing and learning is - based on multiple cues: linguistic (such as lexical, syntactic), but also discourse, prosody, face and hands (gestures). Yet, our understanding of how language is learnt and processed, and its associated neural circuitry, comes almost exclusively - from reductionist approaches in which the multimodal signal is reduced to speech or text. ECOLANG will pioneer a new way to study language comprehension and learning using a real-world approach in which language is analysed in its rich face-to-face - multimodal environment (i.e., language’s ecological niche). Experimental rigour is not compromised by the use of innovative technologies (combining automatic, manual and crowdsourcing methods for annotation; creating avatar stimuli for our - experiments) and state-of-the-art modelling and data analysis (probabilistic modelling and network-based analyses). ECOLANG studies how the different cues available in face-to-face communication dynamically contribute to processing and learning in - adults, children and aphasic patients in contexts representative of everyday conversation. We collect and annotate a corpus of naturalistic language which is then used to derive quantitative informativeness measures for each cue and their combination - using computational models, tested and refined on the basis of behavioural and neuroscientific data. We use converging methodologies (behavioural, EEG, fMRI and lesion-symptom mapping) and we investigate different populations (3-4 years old children, - healthy and aphasic adults) in order to develop mechanistic accounts of multimodal communication at the cognitive as well as neural level that can explain processing and learning (by both children and adults) and can have impact on the rehabilitation - of language functions after stroke. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - ECOLANG - - - ERC-2016-ADG - - - 743035 - - - - - TAMPEREEN YLIOPISTO - - - EUR 191 325,60 - - - Understanding the impact of EU policies on the deinstitutionalization of child care in non-EU Eastern European countries - - - EUR 191 325,60 - - - Finland - - - Higher or Secondary Education Establishments - - The project will investigate the effects of EU policies on the deinstitutionalization of child care in non-EU countries of Eastern Europe. These countries have large numbers of children in orphanages and, in recent years, have - been moving towards family-based child care policies. The study will be conducted in two parts. Firstly, a unique dataset on national deinstitutionalization reforms and relevant EU interventions in Armenia, Azerbaijan, Georgia, Belarus, Moldova, - Ukraine, and Russia will be gathered. After conducting a correlation analysis on these data two countries will be chosen by the positive deviance method, that is, by finding particularly successful countries. These will be further studied using - in-depth interviews of NGOs, government officials and international agencies in order to understand how progress has been achieved and what combinations of factors were key to the success of the reforms. This analysis will lead to an in-depth - understanding of the drivers of deinstitutionalization in these countries, and will help inform EU policies towards the region. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - Finland - - - EUCHILD - - - H2020-MSCA-IF-2016 - - - 742981 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 2 499 149 - - - CLOTH manIpulation Learning from DEmonstrations - - - EUR 2 499 149 - - - Spain - Spain - - - Research Organisations - Research Organisations - - Textile objects pervade human environments and their versatile manipulation by robots would open up a whole range of possibilities, from increasing the autonomy of elderly and disabled people, housekeeping and hospital - logistics, to novel automation in the clothing internet business and upholstered product manufacturing. Although efficient procedures exist for the robotic handling of rigid objects and the virtual rendering of deformable objects, cloth manipulation - in the real world has proven elusive, because the vast number of degrees of freedom involved in non-rigid deformations leads to unbearable uncertainties in perception and action outcomes. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Spain - - - CLOTHILDE - - - ERC-2016-ADG - - - 741930 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 195 454,80 - - - Multi State Memory in Artificial Multiferroics - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Our digital universe is doubling in size every two years, so that by 2020, it will contain nearly as many digital bits as there are stars in our physical universe! Existing memory technologies are approaching their physical - storage limitations as miniaturisation of electronic devices continues. This requires significant development of advanced next generation data storage technologies to sustain consumer demand for increasing levels of data creation. New materials and - technology to store more data in smaller area are required. There is a strong argument in favour of investing in multiferroic material that is still at a distance from a marketable position. In this proposed project we will investigate the prospect - of exchange bias coupled artificial multiferroic material for high density memory device to overcome the market demand. - - 2020-02-29, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - MuStMAM - - - H2020-MSCA-IF-2016 - - - 745886 - - - - - ECOLE DES HAUTES ETUDES EN SCIENCES SOCIALES - - - EUR 173 076 - - - Aural Paris: The Changing Identities of The City of Sound in Music, Film and Literature, 1870-1940. - - - EUR 173 076 - - - France - - - Higher or Secondary Education Establishments - - This project examines the creative assimilation of the city of Paris into the music, film and literature of the French Third Republic (1870-1940). In this period, demarcated by two war defeats, France had to find its new place - within global politics, and the arts participated vividly in these debates. As the city of Paris changed rapidly from a world-leading metropolis to an impoverished city in need of architectural, political and moral reconstruction, its symbols - acquired different connotations. This changing backdrop offers the ground for the study, which analyses how singer/songwriters, composers, authors and filmmakers —such as Victor Fournel, Aristide Bruant, Jean Cocteau, Gustave Charpentier, René Clair - and Pierre Mac Orlan— used the city and its sounds as creative force and political metaphor. The study of overlooked, or totally ignored, archival sources and cultural artefacts will enlighten our knowledge of how street culture and city life - intersected with art. The proposed research plan analyses ‘panoramic literature’ in the late 19th century, the development of the city as a musical stage, the corpus of compositions about Paris, street music and sound in the transition from silent to - sound cinema, and the composition of populist Parisian songs by authors of urban life-writing. The project allows us to re-evaluate the politics of the city soundscape and its role in defining French identity. It also reassesses established notions - of modernity and its interaction with the urban context though the study of everyday sounds and music. By embracing novel ecomusicological methodologies, this project is timely in joining current debates within musicology and cultural geography on - the capacities of sound to produce a sense of space and place. The research will create orthodox academic outputs, exploit novel dissemination and communication strategies, and consolidate an international interdisciplinary network on urban - musicology. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - Aural Paris - - - H2020-MSCA-IF-2016 - - - 750086 - - - - - KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW - KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW - - - EUR 2 500 000 - - - A single-cell genomics approach integrating gene expression, lineage, and physical interactions - - - EUR 2 500 000 - - - Netherlands - Netherlands - - - Research Organisations - Research Organisations - - From populations of unicellular organisms to complex tissues, cell-to-cell variability in phenotypic traits seems to be universal. To study this heterogeneity and its biological consequences, researchers have used advanced - microscopy-based approaches that provide exquisite spatial and temporal resolution, but these methods are typically limited to measuring a few properties in parallel. On the other hand, next generation sequencing technologies allow for massively - parallel genome-wide approaches but have, until recently, relied on studying population averages obtained from pooling thousands to millions of cells, precluding genome-wide analysis of cell-to-cell variability. Very excitingly, in the last few years - there has been a revolution in single-cell sequencing technologies allowing genome-wide quantification of mRNA and genomic DNA in thousands of individual cells leading to the convergence of genomics and single-cell biology. However, during this - convergence the spatial and temporal information, easily accessed by microscopy-based approaches, is often lost in a single-cell sequencing experiment. The overarching goal of this proposal is to develop single-cell sequencing technology that retains - important aspects of the spatial-temporal information. In particular I will focus on integrating single-cell transcriptome and epigenome measurements with the physical cell-to-cell interaction network (spatial information) and lineage information - (temporal information). These tools will be utilized to (i) explore the division symmetry of intestinal stem cells in vivo; (ii) to reconstruct the cell lineage history during zebrafish regeneration; and (iii) to determine lineage relations and the - physical cell-to-cell interaction network of progenitor cells in the murine bone marrow. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Netherlands - - - IntScOmics - - - ERC-2016-ADG - - - 742225 - - - - - VIB - VIB - - - EUR 2 500 000 - - - Preclinical concept validation of tumor endothelial cell metabolism for novel anti-angiogenic therapy - - - EUR 2 500 000 - - - Belgium - Belgium - - - Research Organisations - Research Organisations - - MAIN GOAL: To characterize the metabolic changes, fuelling growth of tumor endothelial cells (TECs) versus normal healthy endothelial cells (NECs), and identify & validate metabolic genes, deregulated in TECs, as targets - for anti-angiogenic cancer therapy. - - - 2022-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Belgium - - - TECNEC - - - ERC-2016-ADG - - - 743074 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 195 454,80 - - - Censoring Chaucer: Canonicity and Obscenity in Manuscripts and Print Editions of the Canterbury Tales (c. 1400 - 1831) - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - This project investigates the relationship between Chaucer's canonical status and his obscenity, both of which have been closely associated with the Canterbury Tales since Chaucer's death in 1400. Readers of the Canterbury - Tales have made note of its occasionally indecorous language and content (particularly in relation to sex, the body, and bodily functions) ever since the earliest surviving manuscript was compiled c. 1405. But whereas obscenity is one of the major - features of Chaucer's reputation in the eyes of present-day readers, many medieval and early modern readers viewed Chaucer’s obscene matter as standing at odds with his canonicity. This project traces the building tension between Chaucer's perceived - obscenity and his literary reputation from his death in 1400 to the publication of poet laureate Robert Southey's expurgated version of the Canterbury Tales in 1831. By examining variations in the language and content of manuscripts, incunables, and - print editions of the Canterbury Tales produced within this period (as well as reader annotations), I will show that scribes, readers, editors, and modernizers of Chaucer's most famous work persistently modify or comment on its language and content - in an effort to downplay (or, occasionally, to enhance) what they perceive as obscene. I situate my findings alongside contemporaneous remarks by writers and editors regarding Chaucer's literary heritage in order to assess the relationship between - variations in his reputation and variations in the Canterbury Tales. The project incorporates intensive training in the study of manuscripts and early printed books, and will result in at least 2 scholarly articles, a book proposal, and several - conference presentations and public engagement initiatives intended to communicate my results to the widest possible audience. A MSCA Fellowship at the University of Oxford will enable me to work closely with a leading expert in the history of the - book over the course of the project. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - Censoring Chaucer - - - H2020-MSCA-IF-2016 - - - 741333 - - - - - UNIVERSITA DEGLI STUDI DI PERUGIA - UNIVERSITA DEGLI STUDI DI PERUGIA - - - EUR 2 895 836 - - - Improving therapy of NPM1-mutated AML - - - EUR 2 895 836 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Acute myeloid leukemia (AML) is the most common acute leukemia in adults accounting for approximately 15,000 new cases/year in Europe and 20,000 new cases/year in US. Currently, 40-50% of AML patients (age 18-60 years) and - only 5-10% of older patients (who are usually more frequently affected by the disease) can be cured using conventional chemotherapy +/- allogeneic hematopoietic stem cell transplantation. Thus, AML still remains an urgent medical need which calls for - new forms of molecular targeted therapies (similarly to those available for acute promyelocytic leukemia). The P.I. previously discovered the nucleophosmin (NPM1) mutations, the most common genetic lesion in AML (about one-third of cases) and gave - fundamental contributions in the translation of this seminal discovery into the clinic (improved classification of myeloid neoplasms according to WHO, genetic-based risk- stratification of AML patients, monitoring of minimal residual disease and - first demonstration of the anti-leukemic activity of actinomycin D). The present research proposal is focused on improving therapy of NPM1-mutated AML. Specifically, it is aimed to: i) identify novel chemical tools interfering with NPM1 functions by - interacting with the N-terminal portion of the protein (objective 1); ii) conduct a clinical trial (AML-PG02; Eudract 2014-003490-41) with actinomycin D in older untreated and/or unfit patients with NPM1-mutated AML and to better understand in vitro - and in mice models the mechanisms of action of this drug, used alone or in combination with other agents (objective 2); iii) develop compound mouse models aimed to investigate how NPM1 mutations cooperate with FLT3-ITD or DNMT3A mutations in - promoting AML with the goal to better understand the characteristics of relapsed cases and to design new therapeutic strategies (objectives 3 and 4): and iv) generate a murine model for testing the feasibility of “in situ” vaccination in AML, - especially in NPM1-mutated AML (objective 5). - - 2022-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Italy - - - TREAT-NPM1-AML - - - ERC-2016-ADG - - - 740230 - - - - - UNIVERSITA DEGLI STUDI DI PERUGIA - UNIVERSITA DEGLI STUDI DI PERUGIA - - - EUR 150 000 - - - Commercialization of a first in class multiple sclerosis drug - - - EUR 150 000 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Multiple sclerosis (MS) is a chronic and progressive neurodegenerative disease that is currently affecting 2.3 million people worldwide. Incidence rates of MS are significantly higher in Europe and in other regions located - within the northern hemisphere. In Europe, the number of patients currently afflicted with MS is estimated to be at 700,000, with incidence rates ranging from 2.3-12.2/100,000 per year. GlobalData assessed the market value for MS treatments in 10 - major markets (France, Germany, Italy, Spain, UK, US, Canada, Japan, China and India) in 2014 to be at €16.2 billion and predicts it to rise to approximately €18.82 billion by 2024. This increase is attributed to the projected sales of newly-approved - drugs. The main shortcoming of current MS treatments ultimately lies in their lack of efficacy, specifically in that they are unable to prevent progressive neurodegeneration in MS patients. MS poses a significant economic burden on society as the - disease affects primarily young people who are in their most economically-productive years. Aside from limited efficacies, current treatment options are also associated with severe side-effects (increased risks of infection, cancer), high costs and - inconvenient administration routes (e.g. intravenous, intramuscular, subcutaneous). The aim of DIDO-MS is to assess the commercial viability of a newly identified small molecule as a drug in the treatment of MS. - - 2019-07-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Italy - - - DIDO-MS - - - ERC-2017-PoC - - - 780807 - - - - - FUNDACION CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III - FUNDACION CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III - - - EUR 2 499 875 - - - Chronic Systemic Inflammation: Functional organ cross-talk in inflammatory disease and cancer - - - EUR 2 499 875 - - - Spain - Spain - - - Research Organisations - Research Organisations - - Chronic Systemic Inflammation (CSI) resulting from systemic release of inflammatory cytokines and activation of the immune system is responsible for the progression of several debilitating diseases, such as Psoriasis, - Arthritis and Cancer. Initially localised diseases can result in CSI with subsequent systemic spread to distant organs, a key patho-physiological phase responsible for major morbidity and even mortality. Despite the importance of CSI, a complete - understanding of the molecular mechanisms, signalling pathways and cell types involved, as well as the chronological evolution of the systemic inflammatory response is still elusive. The classical approach to study inflammation has focused on - investigating individual cell types or organs in the pathogenesis of a single disease, thereby neglecting important organ cross-talk and systemic interactions. Furthermore, understanding the temporal and spatial kinetics modulating the inflammatory - response requires a detailed study of interactions between different immune and non-immune organs at various time points during disease progression in the context of the whole organism. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Spain - - - CSI-Fun - - - ERC-2016-ADG - - - 741888 - - - - - THERAPANACEA - THERAPANACEA - - - EUR 150 000 - - - Fast, Digital Adaptive Personalized Radiotherapy - - - EUR 150 000 - - - France - France - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - TheraPanacea seeks to provide digital, innovative, patient-specific, and adaptive radiotherapy treatment planning system. Our objectives are the following: (i) improve the quality of treatment towards increasing the survival - rate, while (ii) reducing the side effects towards diminishing the disastrous long term radiation impact and (iii) improving the efficiency of device use towards increasing significantly the number of patients being treated. - - 2019-04-30, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - France - - - TheraPanacea - - - ERC-2016-PoC - - - 737604 - - - - - FACULTY OF BIOLOGY OF THE UNIVERSITY OF BELGRADE - YEDITEPE UNIVERSITY VAKIF - ITA-SUOMEN YLIOPISTO - ARGENIT AKILLI BILGI TEKNOLOJILERI SANAYI VE TICARET LIMITED SIRKETI - ELVESYS SAS - FUNDACION CENTRO DE ALTA TECNOLOGIA - UNIVERSITY OF CONNECTICUT - THE UNIVERSITY OF CHICAGO - - - EUR 954 000 - - - AUTOMATED FUNCTIONAL SCREENING OF IgGs FOR DIAGNOSTICS OFNEURODEGENERATIVE DISEASES - - - EUR 954 000 - - - Serbia - Turkey - Finland - Turkey - France - Costa Rica - United States - United States - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The project proposes to organize the exchange of staff of three Academic institutions from Serbia (coordinator), Turkey and Finland, two SMEs from France and Turkey and three TC institutions (two from USA and one from Costa - Rica) towards the production of an innovative automated multifunctional device for diagnostics of neurodegenerative diseases. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Serbia - - - AUTOIGG - - - H2020-MSCA-RISE-2017 - - - 778405 - - - - - UNIVERSITY OF PLYMOUTH - CHALMERS TEKNISKA HOEGSKOLA AB - Phranakhon Rajabhat University - TRUONG DAI HOC TON DUC THANG - SHENZHEN UNIVERSITY - - - EUR 450 000 - - - Tailor-made Recycled Aggregate Concretes - - - EUR 450 000 - - - United Kingdom - Sweden - Thailand - Vietnam - China - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Concrete is the main construction material used on earth. The increasing population and urbanization has led to construction of new high-rise buildings and demolishing existing old low-rise ones. This has become not only the - cause of natural resources depletion at an alarming rate but also gradually becoming a challenge for environmental preservation. Concrete industry consumes a majority of natural resources and produces a large amount of construction waste. In order to - ensure sustainable, cost-effective but still profitable concrete production, extensive research is needed to investigate how concrete industry can produce green concrete by using less nature resources and producing less waste. The aim of the proposed - research is to develop tailor-made concretes by using more recycled concrete aggregate (RCA) for structural applications. The use of RCA as granular material in pavement design has been a long history. However its use in structure concrete has not - been widely accepted, primarily due to the poor quality found in RCA. To overcome this technical difficulty one has to understand the behaviour of RCA and to find a way in which the quality of the RCA can be improved and controlled during its mixing - process. This requires a systematic research into various specific aspects of RCA and recycled aggregate concrete products. This proposed RISE programme is to bring together an international team of researchers with a wide variety of skills, to - tackle the challenges faced by construction industry. The proposed research covers the fundamental study of cementitious materials as well as their applications in different construction fields. The outcome of the research will provide vital - information on how to revolutionise the production of concrete materials and how to engineer concrete mixes using various different components to tailor-made the properties of the resulting concrete. - - 2022-06-30, Grant Agreement signed - - - 2018-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - United Kingdom - - - TRAC - - - H2020-MSCA-RISE-2017 - - - 777823 - - - - - VILNIAUS UNIVERSITETAS - Institute of Applied Physics of the Academy of Sciences of Moldova - ELEKTRONIKOS PERDIRBIMO TECHNOLOGIJOS UAB - INTREPRINDEREA MIXTA UZINA TOPAZ SA - CLARKSON UNIVERSITY - BELARUSIAN STATE UNIVERSITY THE RESEARCH INSTITUTE OF PHYSICAL CHEMICAL PROBLEMS - - - EUR 598 500 - - - Multiscaled Smart Metallic and Semiconductor Electrodes for Electrochemical Processing and Devices - - - EUR 684 000 - - - Lithuania - Moldova - Lithuania - Moldova - United States - Belarus - - - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - - Demand of “smart” electrodes/systems has recently increased due to significant role of various devices/equipment based on these electrodes - urgent needs of present and forthcoming human activities. The multi- and - interdisciplinary project SMARTELECTRODES is proposing elaboration of advanced systems covered under umbrella of “smart” electrodes which will be involved and play significant roles in several important electrochemical/electrophysical applications as - catalysis/electrocatalysis, sensoring, thermoelectrics, electrowinning, electrochemical machining and electrospark alloying. The development of multiscaled (from nano- to macro-; from nanodot to volumized 3D-) metallic and semiconductor electrodes - and integration of them into working systems/equipment is the main target of SMARTELECTRODES. The project is well-balanced, highly innovative R&D training network, which aims: - - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Lithuania - - - SMARTELECTRODES - - - H2020-MSCA-RISE-2017 - - - 778357 - - - - - WEIZMANN INSTITUTE OF SCIENCE - WEIZMANN INSTITUTE OF SCIENCE - - - EUR 2 000 000 - - - Deciphering the Molecular Foundations and Functional Competence of Alternative Human Naïve Pluripotent Stem Cells - - - EUR 2 000 000 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - An important goal of stem cell therapy is to create “customized” cells that are genetically identical to the patient, which upon transplantation can restore damaged tissues. Such cells can be obtained by in vitro direct - reprogramming of somatic cells into embryonic stem (ES)-like cells, termed induced pluripotent stem cells (iPSC). This approach also opens possibilities for modelling human diseases in vitro. However, major hurdles remain that restrain fulfilling - conventional human iPSC/ESC potential, as they reside in an advanced primed pluripotent state. Such hurdles include limited differentiation capacity and functional variability. Further, in vitro iPSC based research platforms are simplistic and iPSC - based “humanized” chimeric mouse models may be of great benefit. - - - 2022-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Israel - - - CELLNAIVETY - - - ERC-2016-COG - - - 726497 - - - - - UNIWERSYTET MEDYCZNY IM KAROLA MARCINKOWSKIEGO W POZNANIU - JOINT STOCK COMPANY FARMAK - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - INSTYTUT FARMACEUTYCZNY - PHYSIOLUTION GMBH - APPLIED PROCESS COMPANY LIMITED - HELSINGIN YLIOPISTO - ZENTIVA, K.S. - RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY - - - EUR 2 268 000 - - - Open Research Biopharmaceutical Internships Support - - - EUR 2 268 000 - - - Poland - Ukraine - Ireland - Poland - Germany - Ireland - Finland - Czech Republic - United States - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - The current process of drug development is lengthy and inefficient. Only 1 out of approximately 10,000 drug molecules enters the market. Therefore more effective medicines, demanded by society, cannot be provided by - pharmaceutical industry. To fill this gap, Open Research Biopharmaceutical Internships Support (ORBIS) proposes that the high attrition rate of new drug candidates might be reduced by over 20% by improving early stage R&D productivity. The - overarching objective of ORBIS is therefore to form an international and inter-sectoral academic and industrial network. The action is aimed at improving the preclinical pathway of medicine development concentrating on processes and technologies. The - goal is to integrate multidisciplinary research by involving academia and industry from EU (Poland, Ireland, Finland, Germany and Czech Republic), EU associated country (Ukraine) and US to address the poor drug bioavailability as 70% of actives have - solubility and/or membrane permeability problems. The action is addressed at selected molecules of class II and IV of Biopharmaceutics Classification System, to improve their pharmaceutical potential. The complementary consortium comprises experts in - computations, physical chemistry, material science, nanotechnology, pharmacy, pharmacology and bioanalysis. The secondments will create a stimulating environment for early stage researchers to advance their individual career and soft skills. EU - scientists will amalgamate their expertise in drug synthesis and dissolution, oral formulations, and bioanalytical methods with the knowledge on dermal research provided by the US partner. ORBIS will consolidate the existing links, promote long-term - cooperation and exchange of knowledge between beneficiaries and partners. ORBIS will also enhance dissemination of new research outcomes and raise the awareness among the general public of the importance of drug delivery research that makes new drugs - more accessible and affordable for society. - - 2022-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Poland - - - ORBIS - - - H2020-MSCA-RISE-2017 - - - 778051 - - - - - UNIVERSITAT AUTONOMA DE BARCELONA - UNIVERSITAT AUTONOMA DE BARCELONA - - - EUR 1 451 264 - - - Migration and Democratic Diffusion: Comparing the Impact of Migration on Democratic Participation and Processes in Countries of Origin - - - EUR 1 451 264 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The objective of this project is to unravel the impact of migration on democratic participation and processes in countries of origin. Both international migration and democratic development are important contemporary public - and policy concerns. Recent studies of transnational migrant practices have uncovered how migrants influence democratic participation in their homelands through the remittance of money and newfound ideas about democracy from afar or through return. - Yet, there is still little comparative knowledge of how these processes intersect with broader economic, social and political transformations in countries of origin. Moreover, complex migration experiences and nonlinear processes of democratization - in countries of origin point to the need for a more nuanced conceptualization of what kind of political ideas circulate and are negotiated among migrants, return migrants and non-migrants in countries of origin. - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Spain - - - MIGRADEMO - - - ERC-2016-COG - - - 726405 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 1 499 611 - - - Refugees are Migrants: Refugee Mobility, Recognition and Rights - - - EUR 1 499 611 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project begins with the basic premise that refugees are migrants: by legal definition and political conception, they have left their home countries to seek refuge. This project aims to re-assess refugee protection through - a lens of mobility and migration, locating the study of refugee law in the context of the refugee regime. It examines the three key aspects of refugee law – access to protection, refugee status determination, and refugee rights – bringing them into - conversation with the refugee regime’s norms and practices on responsibility-sharing and solutions. Crucially, the project takes a long and broad view of refugee protection, in order to open up new possibilities and trajectories. It also integrates a - legal assessment of the role of non-state actors in refugee protection. Using the broad notion of ‘intermediary’ in the migration process, it will assess the regulatory environment on access to protection, so-called ‘secondary movement’ and onward - migration. It will provide an important legal assessment of the role of the International Organisation for Migration (IOM) and the duties of humanitarian actors in refugee protection. It addresses the EU, not as a singularity, but as an actor in the - global regime. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - REF-MIG - - - ERC-2016-STG - - - 716968 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 1 992 578 - - - Innovative technology solutions to explore effects of the microbiome on intestine and brain pathophysiology - - - EUR 1 992 578 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The human gut is host to over 100 trillion bacteria that are known to be essential for human health. Intestinal microbes can affect the function of the gastrointestinal (GI) tract, via immunity, nutrient absorption, energy - metabolism and intestinal barrier function. Alterations in the microbiome have been linked with many disease phenotypes including colorectal cancer, Crohn’s disease, obesity, diabetes as well as neuropathologies such as autism spectrum disorder - (ASD), stress and anxiety. Animal studies remain one of the sole means of assessing the importance of microbiota on development and well-being, however the use of animals to study human systems is increasingly questioned due to ethics, cost and - relevance concerns. In vitro models have developed at an accelerated pace in the past decade, benefitting from advances in cell culture (in particular 3D cell culture and use of human cell types), increasing the viability of these systems as - alternatives to traditional cell culture methods. This in turn will allow refinement and replacement of animal use. In particular in basic science, or high throughput approaches where animal models are under significant pressure to be replaced, in - vitro human models can be singularly appropriate. The development of in vitro models with microbiota has not yet been demonstrated even though the transformative role of the microbiota appears unquestionable. The IMBIBE project will focus on using - engineering and materials science approaches to develop complete (i.e. human and microbe) in vitro models to truly capture the human situation. IMBIBE will benefit from cutting edge organic electronic technology which will allow real-time monitoring - thus enabling iterative improvements in the models employed. The result from this project will be a platform to study host-microbiome interactions and consequences for pathophysiology, in particular, of the GI tract and brain. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - IMBIBE - - - ERC-2016-COG - - - 723951 - - - - - UNIVERSIDAD CARLOS III DE MADRID - UNIVERSITE DE LORRAINE - TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY - INSTYTUT PODSTAWOWYCH PROBLEMOW TECHNIKI POLSKIEJ AKADEMII NAUK - TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK - University of Florida - Texas A&M University - BATTELLE MEMORIAL INSTITUTE NON PROFIT CORPORATION - - - EUR 153 000 - - - Unraveling the role of anisotropy in material failure - - - EUR 153 000 - - - Spain - France - Israel - Poland - United States - United States - United States - United States - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - The overall objective of the QUANTIFY action is to form an international network of 8 organisations, working on a joint research programme in the field of Solid Mechanics. The 8 organisations (4 European beneficiaries and 4 US - partner organisations) will exchange and share skills and knowledge with the view to understand and model the effect of anisotropy in the dynamic mechanical failure of lightweight metallic materials used in the transportation and civilian-security - industries. Breakthroughs in this field will allow lightweight metals fabricated with microstructure optimization techniques and additive manufacturing to replace steel and heavy alloys in manufacturing high structural responsibility components for - automobiles, ships, aircrafts and civil infrastructures, all sectors of crucial importance for the European economy and society. The staff members who participate in the project will be exposed to new research environments and develop new skills, - thus contributing to their increased employability and supporting research in Europe. The 8 organisations will further strengthen their knowledge base, and (further) develop lasting collaborations. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2017 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Spain - - - QUANTIFY - - - H2020-MSCA-RISE-2017 - - - 777896 - - - - - UNIVERSITEIT VAN AMSTERDAM - UNIVERSITEIT VAN AMSTERDAM - - - EUR 1 998 004 - - - Healthscaping Urban Europe: Bio-Power, Space and Society, 1200-1500 - - - EUR 1 998 004 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Medieval public health is mired in modern myth: without centralized governments, democratic values and advanced medicine, promoting health at the population level was purportedly either unthinkable or simply impractical. - Offering a radically different view, HealthScaping will document, analyze and disseminate knowledge about preventative public healthcare between 1200-1500, an era of accelerated urbanization followed by massive demographic decline, with the onset of - Black Death (1347-51). This long-term and comparative perspective will fundamentally revise the narrative of European public health by tracing the development and impact of pertinent government policies, medical discourses and social and religious - action in the continent’s two most urbanized and richly documented regions, Italy and the Low Countries. The project taps numerous written, material and visual sources and archaeological data from several sites, and examines them also by critically - engaging the insights of governmentality studies, cultural-spatial analysis and actor-network theory. A multidisciplinary team, working in a Geographical Information Systems environment and generating innovative urban health maps, will recover - earlier societies’ struggles with domestic and industrial waste, travel and labor hazards, food quality, and social and religious behaviors considered harmful or dangerous. As such, the project’s implications will be broad and profound, for it will - 1) dislodge bio-power from its accustomed place in modernity; 2) historicize the concept of the public sphere from a health perspective; and 3) challenge the privileged role given to epidemic disease as a catalyst for environmental interventions in - premodernity. It will also 4) generate new insights for public health scholars and practitioners working today around the globe, by rethinking the feasibility of preventative interventions under highly diverse forms of government, culture and - topography. - - 2022-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - HealthScaping - - - ERC-2016-COG - - - 724114 - - - - - UNIVERSITEIT LEIDEN - UNIVERSITEIT LEIDEN - - - EUR 150 000 - - - Hypoxic Tumour Models for Photoactivatable Ruthenium-based Chemotherapy - - - EUR 150 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In this Proof-of-Concept project I will show the commercial potential of ruthenium-based photoactivated chemotherapy (PACT) compounds developed in my ERC Starting Grant by demonstrating their efficacy on hypoxic cancer models. - Photoactivated chemotherapy is a new class of phototherapy to treat cancer. In principle, PACT looks similar to photodynamic therapy (PDT): light irradiation of the tumour in vivo leads to local activation of the anticancer prodrug, thereby limiting - the toxicity of the treatment to the diseased tissue, and thus lowering side effects for the patient. However, the mechanisms of PACT and PDT are very different: in PDT the light-absorbing prodrug requires molecular oxygen to kill the cancer cells, - whereas in PACT oxygen is not involved in prodrug activation. As a consequence, PACT agents should be able to treat hypoxic tumours, which are characterized by low oxygen concentrations and high resistance to PDT and other existing therapies. In this - project the efficacy of a selection of Ru-based PACT compounds will be tested in hypoxic cancer models and compared to their efficacy in normoxic conditions. In parallel I will develop, in collaboration with my network of collaborators from the - clinics, business analysts, and patent attorney, a plan for (pre) clinical development of PACT compounds. - - 2019-03-31, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Netherlands - - - HypoRuLight - - - ERC-2017-PoC - - - 768166 - - - - - STICHTING VU - STICHTING VU - - - EUR 1 999 823 - - - Regulating mixed intimacies in Europe - - - EUR 1 999 823 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project is a study of the regulation of ‘mixture’(‘interracial’ sex, relationships and marriage) in Europe’s past and present. Informed by critical race and critical mixed race studies, it challenges the common assumption - that Europe never had ‘anti-miscegenation’ laws comparable to those in the United States. In exploring if, when, how and why forms of regulation aiming to prevent or restrict ‘interracial mixture’ developed in Europe in certain times and places, the - project delivers a vital contribution to our knowledge of the development of racial thinking in Europe. The concept of ‘mixture’ provides an eminently suitable approach to the construction of ‘race’, since ‘mixture’ confuses and destabilizes - racialized categories that seem fixed and essentialized in specific times and places, such as ‘black/white’. - - - 2022-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - EUROMIX - - - ERC-2016-COG - - - 725238 - - - - - Heinrich-Pette-Institute, Leibniz-Institut fuer experimentelle Virologie - Heinrich-Pette-Institute, Leibniz-Institut fuer experimentelle Virologie - - - EUR 1 999 000 - - - Sampling Protein cOmplex Conformational Space with native top down Mass Spectrometry - - - EUR 1 999 000 - - - Germany - Germany - - - Research Organisations - Research Organisations - - The main question to be addressed by SPOCk’S MS is how protein complex conformation adapts to local changes, such as processing of polyproteins, protein phosphorylation or conversion of substrates. While labelling strategies - combined with mass spectrometry (MS), such as hydrogen deuterium exchange and hydroxyl footprinting, are very versatile in studying protein structure, these techniques are employed on bulk samples averaging over all species present. SPOCk’S MS will - remedy these by studying the footprinting and therefore exposed surface area on conformation and mass selected species. Labelling still happens in solution avoiding gas phase associated artefacts. The labelling positions are then read out using newly - developed top-down MS technology. Ultra-violet and free-electron lasers will be employed to fragment the protein complexes in the gas phase. In order to achieve the highest possible sequence and thus structural coverage, lasers will be complemented - by additional dissociation and separation stages to allow MS^N. SPOCk’S MS will allow sampling conformational space of proteins and protein complexes and especially report about the transient nature of protein interfaces. Constraints derived in MS - will be fed into a dedicated software pipeline to derive atomistic models. SPOCk’S MS will be used to study intracellular viral protein complexes, especially coronaviral replication/transcription complexes, which are highly flexible and often resist - crystallisation and are barely accessible by conventional structural biology techniques. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - SPOCkS MS - - - ERC-2017-STG - - - 759661 - - - - - ERNST-MORITZ-ARNDT-UNIVERSITÄT GREIFSWALD - ERNST-MORITZ-ARNDT-UNIVERSITÄT GREIFSWALD - - - EUR 1 498 749 - - - Evolution of artificial enzymes for light-driven reactions by implementing unnatural cofactors in protein scaffolds - - - EUR 1 498 749 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The LightZymes project aims to create artificial enzymes (LightZymes) catalyzing selective light-driven conversions of small organic molecules. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - LightZymes - - - ERC-2017-STG - - - 759262 - - - - - STICHTING VU - STICHTING VU - - - EUR 1 709 240 - - - Quantifying Recycling Fluxes of Earth Surface Materials and Volatiles in Subduction Zones using Melt Inclusions - - - EUR 1 709 240 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Plate tectonics are fundamental to the geochemical cycles that link Earth’s mantle and exosphere and in turn control the atmosphere’s composition and our climate. Currently a major unknown is the exact fate of surface - materials at destructive plate-tectonic boundaries (subduction zones). Specifically, what proportions of volatiles, sediments and oceanic crust are transported into the deep mantle, or are returned, i.e. ‘recycled’ to the crust and atmosphere. Global - recycling flux estimates, including carbon, are contradictory highlighting the need for a new, more precise approach to their quantification. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - ReVolusions - - - ERC-2017-STG - - - 759563 - - - - - Institute of Science and Technology Austria - Institute of Science and Technology Austria - - - EUR 1 498 394 - - - Probing the Reversibility of Autism Spectrum Disorders by Employing in vivo and in vitro Models - - - EUR 1 498 394 - - - Austria - Austria - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Autism Spectrum Disorders (ASD) are a group of neurological conditions characterized by stereotypical or repetitive behaviours as well as impairments in social interaction and communication skills, often of genetic basis. ASD - have been classified as neurodevelopmental disorders, implying irreversible defects in the maturation of neural circuits. We have shown that mutations in the Branched Chain Ketoacid Dehydrogenase Kinase (BCKDK) gene lead to a potentially preventable - and reversible form of ASD (Novarino et al. Science 2012). The most direct consequence of BCKDK mutations is a hyper-metabolism of the branched chain amino acids (BCAAs), resulting in atypically low levels of serum and brain BCAAs. Recently, using - whole exome sequencing we identified individuals with ASD carrying mutations in the gene SLC7A5, encoding for the transporter mediating BCAA flux across the blood brain barrier. This suggests that the BCAAs are critical for brain development and - cognition and reinforces their link with ASD. The simple nature and availability of the BCAAs prompt raising the possibility that this group of amino acids may be employed to treat symptoms of other ASD. We aim at 1) elucidating the link between - BCAAs, ASD, brain development and cognition; 2) exploring the possibility of employing the BCAAs to reverse symptoms caused by mutations of ASD-genes. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Austria - - - REVERSEAUTISM - - - ERC-2016-STG - - - 715508 - - - - - STOCKHOLMS UNIVERSITET - STOCKHOLMS UNIVERSITET - - - EUR 1 491 966,75 - - - SUNMAG: Understanding magnetic-field-regulated heating and explosive events in the solar chromosphere - - - EUR 1 491 966,75 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project represents a new powerful approach to a fundamental problem in solar physics: the heating of the solar chromosphere. The aim of SUNMAG is to identify the mechanisms that heat the chromosphere and characterize the - energy flux that is being released into the outer layers of the Sun in active regions and flares. By investigating how the chromosphere regulates the energy and mass transport we can also contribute to an understanding of the heating of the corona - and the acceleration of the solar wind. These goals are finally within reach thanks to the recent developments of numerical simulations and analysis codes for observations and, observationally, thanks to the very recent development of a new powerful - instrument for imaging spectroscopy (CHROMIS) that allows to study the upper chromosphere at the highest possible spatial resolution. - - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Sweden - - - SUNMAG - - - ERC-2017-STG - - - 759548 - - - - - STOCKHOLMS UNIVERSITET - STOCKHOLMS UNIVERSITET - - - EUR 1 299 165 - - - Micro Heterogeneity and Macroeconomic Policy - - - EUR 1 299 165 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project will develop macroeconomic models with household heterogeneity and partially demand-determined output to study how the economy is affected by monetary and fiscal policy, and to investigate the importance of - housing in macroeconomic fluctuations and the transmission and efficacy of policy. The objective is to provide a modelling framework that simultaneously is consistent with both empirical micro evidence on household consumption and savings behaviour, - and macro evidence on the response of the aggregate economy to a variety of economic shocks. The ultimate goal is to help make these models the new standard for the study of fluctuations and policy evaluation in macro. - - 2022-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Sweden - - - MICROTOMACROANDBACK - - - ERC-2017-STG - - - 759482 - - - - - UNIVERSIDAD PABLO DE OLAVIDE - UNIVERSIDAD PABLO DE OLAVIDE - AKSE HENDRIK - - - EUR 150 000 - - - Enhancing Separation Efficiency in European Syngas Industry by using Zeolites - - - EUR 150 000 - - - Spain - Spain - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Syngas is traditionally used in industry for production of fuels in the kerosene, gasoline and diesel range via Fischer-Tropsch, for the manufacture of bulk chemicals like ammonia, methanol and dimethyl ether and for synthesis - of a whole array of fine chemicals. The hydrogen /carbon monoxide ratio of the syngas is an important design variable to maximize production of these compounds. Therefore, the search of effective processes that enable said ratio adjustment as well as - individual compound purification is an essential and ongoing effort for industry. The Proof of Concept that we propose is the development of a zeolite-based separation process to obtain carbon dioxide-neutral fuels and chemicals. The process that we - plan to design is based on gas uptake and release, combining separation efficiency with low separation costs. Our approach consists of three main steps: identification of the optimal zeolite structure; validation with experiments and initiation of - commercialization by developing a Business Case. For the technical testing, we will use the research knowledge developed within the ERC-RASPA project, and the resulting process will be validated for the separation of carbon dioxide, carbon monoxide - and oxygen resulting from plasma-assisted dissociation of the former gas into the others. The competitive analysis, business case and commercialization will be performed with the Company Traxxys Innovation and Sustainability as a partner. End user - companies and equipment manufacturers such as Bronswerk (NL) and Hidralia (Sp) have expressed their interest in the idea. - - 2019-06-30, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Spain - - - ZEOSEP - - - ERC-2017-PoC - - - 779792 - - - - - TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY - TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY - - - EUR 150 000 - - - Autonomous Nanosatellite-Clusters Control, Coordination and Communication Software - - - EUR 150 000 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Coordinated operation of clusters of nanosatellites can potentially revolutionize the space sector; however, until recently, performing long-term satellite cluster flight was thought to be impractical, since existing orbital - control methods required too much fuel. During the FADER ERC Starting Grant, our team was able to develop autonomous cluster flight algorithms capable of preserving the relative geometry and communication links among satellites in a cluster for - mission lifetimes exceeding a year, while utilizing minimal amounts of fuel. Moreover, we developed cluster flight algorithms that do not require propulsion systems at all, demonstrating the usage of atmospheric drag to maintain clusters of - satellites in low Earth orbits, while keeping distance constraints among satellites. Utilizing these newly-developed algorithms, nanosatellite clusters can yield the performance of a conventional large satellite for a fraction of the cost, and - greatly improve mission and/or science return. The FADER algorithms were subsequently implemented as a prototype on SAMSON, the first triple-nanosatellite autonomous cluster flight mission, scheduled to be launched in 2018. - - 2019-04-30, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Israel - - - NanoC4 - - - ERC-2017-PoC - - - 779754 - - - - - UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA - UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA - - - EUR 150 000 - - - IN VItro Cavitation Through UltraSound - - - EUR 150 000 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Disorders of the central nervous system (CNS) contribute almost 800 billion euros in annual European healthcare costs. New compounds, effective in animal models, hardly work in humans, mostly due to the inability to cross the - Brain Blood Barrier (BBB). In these conditions cost-effective tools to alter BBB and, more generally, endothelial layer permeability is desirable before proceeding to expensive and time-consuming animal studies. INVICTUS (IN VItro Cavitation Through - UltraSound) originates within the ERC-AdG project Bubbles from Inception to Collapse (BIC) and concerns the development of a biomimetic micro-fluidic platform to be made turnkey available to biologists, clinicians and pharmacologists. The integrated - platform exploits endothelial layer permeability enhancement by cavitation bubbles and provides an integrated, low cost platform to develop cavitation enhanced drug delivery under well controlled and reproducible conditions. Its potential is - significant, given the well known societal and economical impact of degenerative diseases and the enormous investment and the long times of pre-clinical trials, as confirmed by a leading company operating in the field. Limiting/avoiding animal - experimentation has an evident ethical impact and is associated with substantial economic savings and organisational simplification. In few words, micro-bubbles injected into the bloodstream undergo volume oscillations under localised ultrasound - irradiation, with local reversible permeability enhancement of the endothelium. Already pursed in in vivo animal models, this approach is extended here to a high-fidelity, in vitro biomimetic device that will bring to market new crucial features such - as the three-dimensional geometry of realistic-size vascular channels featuring an actual endothelial barrier, the correct perfusion rate, the appropriate physiological shear stress exerted on the endothelial cells and the ability to reproduce - biochemical interactions between different, healthy and diseased, tissues. - - 2019-05-31, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Italy - - - INVICTUS - - - ERC-2017-PoC - - - 779751 - - - - - TECHNISCHE UNIVERSITAET BERGAKADEMIE FREIBERG - TECHNISCHE UNIVERSITAET BERGAKADEMIE FREIBERG - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 499 145 - - - A Multiscale Dislocation Language for Data-Driven Materials Science - - - EUR 1 499 145 - - - Germany - Germany - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - Crystalline defects in metals and semiconductors are responsible for a wide range of mechanical, optical and electronic properties. Controlling the evolution of dislocations, i.e. line-like defects and the carrier of plastic - deformation, interacting both among themselves and with other microstructure elements allows tailoring material behaviors on the micro and nanoscale. This is essential for rational design approaches towards next generation materials with superior - mechanical properties. - - 2022-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - MuDiLingo - - - ERC-2017-STG - - - 759419 - - - - - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - - - EUR 1 500 000 - - - Charting the space of Conformal Field Theories: a combined nuMerical and Analytical aPproach - - - EUR 1 500 000 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Conformal Field Theory (CFT) was originally conceived in four and three dimensions, with applications to particle physics and critical phenomena in mind. However, it is in two dimensions that the most spectacular results have - been obtained. In higher dimensions, there used to be a general feeling that the constraining power of conformal symmetry by itself is insufficient to tell nontrivial things about the dynamics. Hence the interest in various additional assumptions. - This is not fully satisfactory, since there are likely many CFTs that do not fulfill any of them. - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Switzerland - - - CFT-MAP - - - ERC-2017-STG - - - 758903 - - - - - WEIZMANN INSTITUTE OF SCIENCE - WEIZMANN INSTITUTE OF SCIENCE - - - EUR 150 000 - - - Fighting Anxiety with Importin-based Therapeutics - - - EUR 150 000 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Anxiety and stress-related conditions represent a significant health burden in modern society. Anxiety disorders are currently treated with a variety of agents targeting synaptic mechanisms. These agents either directly affect - neurotransmitter receptor systems or modulate neurotransmitter levels or availability, but their long-term use is limited by problematic side effects and suboptimal efficacy. The development of new anxiolytic drugs has been fraught with difficulty, - hence there is a need for new targets and new avenues for therapeutic development. - - 2019-04-30, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Israel - - - FAITh - - - ERC-2017-PoC - - - 767058 - - - - - UNIVERSITA CA' FOSCARI VENEZIA - UNIVERSITA CA' FOSCARI VENEZIA - - - EUR 1 343 175 - - - Florilegia Syriaca. The Intercultural Dissemination of Greek Christian Thought in Syriac and Arabic in the First Millennium CE - - - EUR 1 343 175 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - FLOS will focus on the metamorphoses of Greek Christian thought in Syriac (Aramaic) and Arabic in Late Antiquity, within the timeframe of the first millennium CE. Syriac Christianity was a pivotal mediator of culture in the - Late Antique epistemic space, but is little-known today. FLOS aims to bring to light for the first time a body of highly relevant Syriac and Christian Arabic sources that have hardly ever been studied before. At the end of the millennium, in - Islamic-ruled Syria, Mesopotamia, and Iran, Syriac Christians strived to define their religious identity. One of their strategies was the production of florilegia, i.e. anthologies that they used to excerpt and reinvent the patristic canon, a corpus - of Greek Christian works of the 2nd–6th centuries shared by European and Middle Eastern Christian cultures. A Greco-centric bias has prevented scholars from viewing these florilegia as laboratories of cultural creativity. FLOS will reverse the state - of the art through two groundbreaking endeavours: 1) open-access digital editions of a set of Syriac florilegia of the 8th–10th centuries; 2) a study of many neglected writings of Syriac and Christian Arabic authors of the 8th–11th centuries. These - tremendously important writings drew from Syriac patristic florilegia to pinpoint topics like incarnation and the Trinity against other Christians or Islam, showing how patristic sources were used to create new knowledge for the entangled environment - of the Abbasid era. FLOS will thus dramatically improve our understanding of the cultural dynamics of Late Antiquity; patristic Christianity will emerge as a bridge between the intellectual history of Europe and of the Middle East. By studying how - this shared patrimony was transformed in situations of interreligious interaction, especially with Islam, FLOS will facilitate the comprehension of Europe’s current religious discourses, and the preservation of the endangered cultural heritage of the - Syriac Christians. - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Italy - - - FLOS - - - ERC-2017-STG - - - 758732 - - - - - CIIMAR - Centro Interdisciplinar de Investigação Marinha e Ambiental - CIIMAR - Centro Interdisciplinar de Investigação Marinha e Ambiental - - - EUR 1 462 938 - - - Fatty acid incorporation and modification in cyanobacterial natural products - - - EUR 1 462 938 - - - Portugal - Portugal - - - Research Organisations - Research Organisations - - Known, but mostly novel natural products (NPs) are in high demand – these are used in drugs, cosmetics and agrochemicals and serve also as research tools to probe biological systems. NP structures inspire chemists to develop - new syntheses, and NP biosynthetic enzymes add to the metabolic engineer’s toolbox. The advent of next generation DNA-sequencing has revealed a vastly rich pool of NP biosynthetic gene clusters (BGCs) among bacterial genomes, most of which with no - corresponding NP. Hence, opportunities abound for the discovery of new chemistry and enzymology that has the potential to push the boundaries of chemical space and enzymatic reactivity. Still, we cannot reliably predict chemistry from BGCs with - unusual organization or encoding unknown functionalities, and, for molecules of unorthodox architecture, it is difficult to anticipate how their BGCs are organized. It is the valuable, truly novel chemistry and biochemistry that lies on these - unexplored connections, that we aim to reveal with this proposal. To achieve it, we will work with a chemically-talented group of organisms – cyanobacteria, and with a specific structural class – fatty acids (FAs) – that is metabolized in a quite - peculiar fashion by these organisms, paving the way for NP and enzyme discovery. On one hand, we will exploit the unique FA metabolism of cyanobacteria to develop a feeding strategy that will quickly reveal unprecedented FA-incorporating NPs. On the - other, we will scrutinize the intriguing biosynthesis of three unique classes of metabolites that we have isolated recently and that incorporate and modify FA-moieties. We will find the BGCs for these compounds and dissect the functionality involved - in such puzzling modifications to uncover important underlying enzymatic chemistry. This proposal is a blend of discovery- and hypothesis-driven research at the NP chemistry/biosynthesis interface that draws on the experience of the PI’s work on - different aspects of cyanobacterial NPs. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Portugal - - - FattyCyanos - - - ERC-2017-STG - - - 759840 - - - - - THE UNIVERSITY OF BIRMINGHAM - THE UNIVERSITY OF BIRMINGHAM - UNIVERSITY OF LEEDS - STICHTING WAGENINGEN RESEARCH - - - EUR 1 493 970 - - - Redefining the carbon sink capacity of global forests: The driving role of tree mortality - - - EUR 1 493 970 - - - United Kingdom - United Kingdom - United Kingdom - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - Everything that lives must die. Yet when it comes to the world's forests, we know much more about the processes governing their life than those governing their death. Global forests hold enormous amounts of carbon in their - biomass, which has absorbed about 20% of anthropogenic carbon dioxide emissions over recent decades. Whether the size of this sink will persist, intensify, decrease or even become a source is highly uncertain, yet knowing this is crucial to the - calculation of carbon emission budgets consistent with limiting global temperature rise. One of the most compelling explanations for this uncertainty is a lack of knowledge of how tree mortality affects forest carbon storage on a global scale. - Mortality rates and mechanisms are closely tied to forest structure and composition, and thus the storage of carbon in biomass, but mechanistic complexity and the difficulty of measurement have hindered understanding, resulting in a striking lack of - consensus in existing assessments. TreeMort will remedy this, combining newly available sources of data with appropriate conceptualisation and innovative modelling, to provide quantifications of the rates and causes of tree death, and their relation - to environmental drivers, that set new standards for robustness, comprehensiveness and consistency at the global scale. This breaking-out of the narrower foci of previous work will be a game-changer, finally enabling globally-comprehensive - investigation of the extent to which whole forest structure and function are governed by and interact with mortality, and their likely evolution under environmental change. TreeMort will assess this using state-of-the-art ecosystem modelling, which - will then be employed to make a fundamental reassessment of the current and future carbon storage capacity of global forests. TreeMort will thus bring us significantly closer to understanding fully how forests interact with the global carbon cycle, - assisting efforts to mitigate climate change. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - TreeMort - - - ERC-2017-STG - - - 758873 - - - - - FONDAZIONE TELETHON - FONDAZIONE TELETHON - - - EUR 1 497 250 - - - Dissecting the regulatory logic of cell fate reprogramming through integrative and single cell genomics - - - EUR 1 497 250 - - - Italy - Italy - - - Research Organisations - Research Organisations - - The concept that any cell type, upon delivery of the right “cocktail” of transcription factors, can acquire an identity that otherwise it would never achieve, revolutionized the way we approach the study of developmental - biology. In light of this, the discovery of induced pluripotent stem cells (IPSCs) and cell fate conversion approaches stimulated new research directions into human regenerative biology. However, the chance to successfully develop patient-tailored - therapies is still very limited because reprogramming technologies are applied without a comprehensive understanding of the molecular processes involved. - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Italy - - - CellKarma - - - ERC-2017-STG - - - 759154 - - - - - INSTITUT PASTEUR - INSTITUT PASTEUR - - - EUR 1 489 147 - - - Competition for Space in Development and Diseases - - - EUR 1 489 147 - - - France - France - - - Research Organisations - Research Organisations - - Developing tissues have a remarkable plasticity illustrated by their capacity to regenerate and form normal organs despite strong perturbations. This requires the adjustment of single cell behaviour to their neighbours and to - tissue scale parameters. The modulation of cell growth and proliferation was suggested to be driven by mechanical inputs, however the mechanisms adjusting cell death are not well known. Recently it was shown that epithelial cells could be eliminated - by spontaneous live-cell delamination following an increase of cell density. Studying cell delamination in the midline region of the Drosophila pupal notum, we confirmed that local tissue crowding is necessary and sufficient to drive cell elimination - and found that Caspase 3 activation precedes and is required for cell delamination. This suggested that a yet unknown pathway is responsible for crowding sensing and activation of caspase, which does not involve already known mechanical sensing - pathways. Moreover, we showed that fast growing clones in the notum could induce neighbouring cell elimination through crowding-induced death. This suggested that crowding-induced death could promote tissue invasion by pretumoural cells. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - CoSpaDD - - - ERC-2017-STG - - - 758457 - - - - - UNIVERSIDAD CARLOS III DE MADRID - UNIVERSIDAD CARLOS III DE MADRID - - - EUR 1 497 506,87 - - - Opening a new route in solid mechanics: Printed protective structures - - - EUR 1 497 506,87 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Dynamic fragmentation of metals is typically addressed within a statistical framework in which material and geometric flaws limit the energy absorption capacity of protective structures. This project is devised to challenge - this idea and establish a new framework which incorporates a deterministic component within the fragmentation mechanisms. - - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Spain - - - PURPOSE - - - ERC-2017-STG - - - 758056 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 499 940 - - - Charge And Spin in TopologicaL Edge States - - - EUR 1 499 940 - - - France - France - - - Research Organisations - Research Organisations - - Topology provides mathematical tools to sort objects according to global properties regardless of local details, and manifests itself in various fields of physics. In solid-state physics, specific topological properties of the - band structure, such as a band inversion, can for example robustly enforce the appearance of spin-polarized conducting states at the boundaries of the material, while its bulk remains insulating. The boundary states of these ‘topological insulators’ - in fact provide a support system to encode information non-locally in ‘topological quantum bits’ robust to local perturbations. The emerging ‘topological quantum computation’ is as such an envisioned solution to decoherence problems in the - realization of quantum computers. Despite immense theoretical and experimental efforts, the rise of these new materials has however been hampered by strong difficulties to observe robust and clear signatures of their predicted properties such as - spin-polarization or perfect conductance. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - CASTLES - - - ERC-2017-STG - - - 758077 - - - - - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - - - EUR 1 499 996 - - - Bacterial persister regrowth - - - EUR 1 499 996 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This proposal aims to provide insight into persister resuscitation. Persisters are multidrug-tolerant cells that are transiently non-growing and able to generate viable offspring by resuming growth when antibiotic pressure is - removed. Despite their implication in relapses of many infectious diseases, and progress in understanding how persisters form through the action of toxin-antitoxin modules, the mechanisms underlying resuscitation of these persisters are still - unknown. The interaction between Salmonella and host macrophages has proven to be a powerful and relevant model to study persister biology since the bacteria specifically respond to engulfment by the host defence cells by forming high proportions of - persisters. Upon encounter with the host, Salmonella activates 14 toxins to arrest growth and persist in this environment. With the recent discovery of a detoxifying enzyme (Pth) counteracting the action of a persister-inducing toxin (TacT), thus - allowing growth resumption of Salmonella persisters, we can now begin to address the pending question of persister regrowth. The consolidation of my research group around the experimental plan proposed here, will enable us to dissect the balance - between intoxication vs. detoxification or entry vs. exit from persistence induced by Tact and Pth respectively. This is the first couple of toxin/detoxifying enzymes to be identified. I intend to extend this knowledge to the whole repertoire of - toxins involved in Salmonella persister formation through systematic identification and characterization of the detoxifying mechanisms allowing resuscitation. Additionally I will investigate the lag phase leading to regrowth of persisters; and target - the toxins involved in persister formation to force persisters out of growth arrest. This work will unravel persister resuscitation and could ultimately provide ways to force persisters out of that state so they become re-sensitized to antibiotics. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - RESUSCITATION - - - ERC-2017-STG - - - 757369 - - - - - UNIVERSITEIT TWENTE - UNIVERSITEIT TWENTE - - - EUR 1 499 691 - - - Scaling up behavior and autonomous adaptation for macro models of climate change damage assessment - - - EUR 1 499 691 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Damage associated with climate change is a core benchmark in science and policy. Macro Integrated Assessment Models estimating damages are criticized for neglecting risk distribution, adaptation dynamics and the possible - collapse of regional economies. Micro-level social science studies contain substantial knowledge on individual behavior, decisions under risk and autonomous climate adaptation, and go beyond monetary losses by focusing on resilience. This knowledge - can ameliorate theoretical and empirical flaws in current macro assessments, if adequate scaling up methods were to exist. - - - 2023-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - SCALAR - - - ERC-2017-STG - - - 758014 - - - - - ALBERT-LUDWIGS-UNIVERSITAET FREIBURG - ALBERT-LUDWIGS-UNIVERSITAET FREIBURG - - - EUR 1 499 101 - - - Emergence of Surface Roughness in Shaping, Finishing and Wear Processes - - - EUR 1 499 101 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Roughness on most natural and man-made surfaces shares a common fractal character from the atomic to the kilometer scale, but there is no agreed-upon understanding of its physical origin. Yet, roughness controls many aspects - of engineered devices, such as friction, adhesion, wear and fatigue. Engineering roughness in surface finishing processes is costly and resource intensive. Eliminating finishing steps by controlling roughness in primary shaping or in subsequent wear - processes could therefore revolutionize the way we manufacture, but this requires a deep understanding of the relevant processes that is presently lacking. Roughness emerges during mechanical deformation in processes such as folding, scratching or - chipping that shape surfaces. Deformation occurs in the form of avalanches, individual bursts of irreversible motion of atoms. The central hypothesis of this project is that roughness is intrinsically linked to these deformation avalanches, which - themselves are well-documented to be fractal objects. This hypothesis will be tested in large-scale atomic- and mesoscale simulations of plastic forming and fracture on state of the art high performance computing platforms. Results of these - calculations will be used to develop process models for evolving the topography of large surface areas under the action of an external mechanical force, such as experienced in shaping, finishing or wear. In addition to these simulations, a public - repository for sharing topography data will be build. This repository is the connection to experiments: It is a database of experimental topographies whose contents will be mined for features identified in simulations. Beyond the present project, - this web-repository will advance sharing, visualization and analysis of topography data, and aid researchers to correlate surface topography with surface functionality and processing. Simulations and database lay the foundation for a rational design - of surface functionality in manufacturing. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - ShapingRoughness - - - ERC-2017-STG - - - 757343 - - - - - CORK INSTITUTE OF TECHNOLOGY - - - EUR 187 866 - - - Training in Quantum Photonics Design Fabrication and Characterisation - - - EUR 187 866 - - - Ireland - - - Higher or Secondary Education Establishments - - The efficient generation of Quantum states of light is a vital task in Quantum Photonics technologies. Current approaches are generally bulky and expensive with low generation rates. The state of art solutions do not scale. - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - Ireland - - - TeRrIFIC - - - H2020-MSCA-IF-2016 - - - 749143 - - - - - ITA-SUOMEN YLIOPISTO - ITA-SUOMEN YLIOPISTO - - - EUR 150 000 - - - Novel algorithm for treatment planning of patients with osteoarthritis - - - EUR 150 000 - - - Finland - Finland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Osteoarthritis (OA) is a common joint disease affecting over 40 million Europeans. Most common consequences of OA are pain, disability and social isolation. What is alarming, the number of patients will increase 50% in - developed countries during the next 20 years. Moreover, the economic costs of OA are considerable since 1) direct healthcare (hospital admissions, medical examinations, drug therapy, etc.) and 2) productivity costs due to reduced performance while at - work and absence from work have been estimated to be between 1% and 2.5% of the gross domestic product (GDP) in Western countries. - - 2019-06-30, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Finland - - - ALGOA - - - ERC-2016-PoC - - - 755037 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 500 000 - - - Regulation of Single Hematopoietic Stem Cells by Intake of Vitamin A - - - EUR 1 500 000 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Quiescence preserves the self-renewal capacity and the long-term function of hematopoietic stem cells (HSCs). The regulators of this dormant state include intrinsic pathways and soluble components in the bone marrow niche. - Dysregulation of this process is poorly defined and might cause aberrant hematopoiesis. In my previous work, we defined the molecular landscape of HSCs by applying state of the art DNA-methylome, RNA-seq and proteome analyses, and found vitamin - A/retinoic acid (RA)-induced signaling predominantly enriched in HSCs (Cabezas-Wallscheid et al., Cell Stem Cell 2014). Intriguingly, we observed that mice fed with a vitamin A-free diet exhibited a robust loss of HSCs (Cabezas-Wallscheid et al., - Cell 2017). Treatment of mice with a RA agonist preserved HSC quiescence in stress-activated conditions, indicating that the balance between HSC maintenance and differentiation is tightly regulated by vitamin A signaling. - - - 2023-04-30, Grant Agreement signed - - - 2018-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - VitASTEM - - - ERC-2017-STG - - - 759206 - - - - - KING'S COLLEGE LONDON - KING'S COLLEGE LONDON - - - EUR 1 500 000 - - - Development of a Novel Computational Toolbox for Stochastic Electronic Structure in Chemistry and Condensed Matter - - - EUR 1 500 000 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Atomistic computational modelling is increasingly an integral component of almost all areas of chemistry, physics and materials science, especially as its predictive ability improves. However, not all systems are equal when it - comes to the predictive capabilities of current methods, and many systems are too large or many-body effects too complex to be routinely tractable. The result is that the promise of ‘materials by design’, deduction of reaction pathways or routine - simulation on a par with experimental accuracy has not in general come to fruition. This ambitious proposal aims to address this, with development of a suite of novel approaches to stochastically sample the wavefunction. Recent work by the PI has - already made huge strides in this direction, with an emerging approach in quantum chemical space having remarkable success for accurate solutions of small problems. Here, we first propose a number of novel developments to order to extend this - approach from a tool for small systems to a widespread disruptive technology, with application to a variety of challenging problems. This involves development of the scope, scaling, accuracy and capabilities of this sampling, including admitting - time-dependent, spectral and relativistic extensions. Next, we aim to take the successful philosophy of this sampling and exploit its powerful approach in order to reformulate a number of well-established electronic structure tools. Allowing - stochasticity has the potential to yield low-scaling formulations of these methods, able to naturally exploit inherent sparsity, and have a revolutionary impact on their use and success. This proposal is highly interdisciplinary, spanning a range of - applications and techniques in quantum chemistry, condensed matter and materials science, brought together under the banner of exploiting inherent sparsity by establishing a new paradigm of stochastic tools for correlated electrons, with the - opportunity for tremendous impact in a number of fields. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - WFNQMC - - - ERC-2017-STG - - - 759063 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 498 000 - - - Insular cortical circuits controlling fear and anxiety - - - EUR 1 498 000 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - How do emotions guide our behaviour? For an appropriate behavioural response, an individual has to constantly integrate bodily feelings, emotional states, and cues from the environment to evaluate the risks and benefits of a - future action. A growing body of evidence indicates that the insular cortex, as part of a distributed neuronal network, plays a key role in influencing emotional behaviour. However, how neuronal circuits within the insular cortex function - mechanistically is not known. - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - InsularAnxiety - - - ERC-2017-STG - - - 758448 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 1 499 940 - - - Mushroom Body Expansion in Heliconius butterflies - - - EUR 1 499 940 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The brain plays a central role in the production of adaptive behaviour. It must extract and integrate the most relevant sensory cues from the environment, and combine this information with memories of past experience to - trigger appropriate behavioural responses. To fully understand the origins of behavioural novelty we need a detailed understanding of how behavioural differences are generated, both across evolutionary time and during development. This requires the - integration of behavioural and neuroanatomical variation, and their genomic and developmental bases. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - MuBoEx - - - ERC-2017-STG - - - 758508 - - - - - UNIVERSITE DU LUXEMBOURG - UNIVERSITE DU LUXEMBOURG - - - EUR 1 687 458 - - - Predicting the effects of gut microbiota and diet on an individual’s drug response and safety - - - EUR 1 687 458 - - - Luxembourg - Luxembourg - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Precision medicine is an emerging paradigm that aims at maximizing the benefits and minimizing the harm of drugs. Realistic mechanistic models are needed to understand and limit heterogeneity in drug responses. Consequently, - novel approaches are required that explicitly account for individual variations in response to environmental influences, in addition to genetic variation. The human gut microbiota metabolizes drugs and is modulated by diet, and it exhibits - significant variation among individuals. However, the influence of the gut microbiota on drug failure or drug side effects is under-researched. In this study, I will combine whole-body, genome-scale molecular resolution modeling of human metabolism - and human gut microbial metabolism, which represents a network of genes, proteins, and biochemical reactions, with physiological, clinically relevant modeling of drug responses. I will perform two pilot studies on human subjects to illustrate that - this innovative, versatile computational modeling framework can be used to stratify patients prior to drug prescription and to optimize drug bioavailability through personalized dietary intervention. With these studies, BugTheDrug will advance - mechanistic understanding of drug-microbiota-diet interactions and their contribution to individual drug responses. I will perform the first integration of cutting-edge approaches and novel insights from four distinct research areas: systems biology, - quantitative systems pharmacology, microbiology, and nutrition. BugTheDrug conceptually and technologically addresses the demand for novel approaches to the study of individual variability, thereby providing breakthrough support for progress in - precision medicine. - - 2023-03-31, Grant Agreement signed - - - 2018-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Luxembourg - - - BugTheDrug - - - ERC-2017-STG - - - 757922 - - - - - MONTANUNIVERSITAT LEOBEN - MONTANUNIVERSITAT LEOBEN - - - EUR 1 499 679 - - - Design of Phase Transition Kinetics in Non-Equilibrium Metals - - - EUR 1 499 679 - - - Austria - Austria - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The first technological use of non-equilibrium phase transitions in metals for designing properties is documented as ~800 BC, but the time has come to make a leap forward. Nearly all classes of materials show non-equilibrium - phase transitions. Understanding how fast these transitions occur is a key question in materials science. In metals, kinetics is connected to diffusion via atomic lattice vacancies. However, there is no universal sound and predictive physical - understanding of the kinetics under non-equilibrium situations so far, because theory cannot be verified experimentally. The in-situ measuring of non-equilibrium vacancy evolution is not possible at industrially relevant and controlled high thermal - rates today. Moreover, direct microscopic observation of vacancies in bulk metals has not yet been achieved. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Austria - - - TRANSDESIGN - - - ERC-2017-STG - - - 757961 - - - - - UNIVERSITEIT LEIDEN - UNIVERSITEIT LEIDEN - - - EUR 150 000 - - - Precise array of proton selective nanopores in 2D atomically thin membranes - - - EUR 150 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Direct methanol fuel cells (DMFCs) are devices expected to power future micro and portable electronic devices as well as vehicles. The lack of efficient proton exchange membranes, however, still prevents the development and - application of DMFCs. Of paramount importance is ion selectivity and fast transmembrane transport, for which nanoporous two-dimensional membranes offer the prospect of enhanced fuel cell performance. Several chemical and physical limitations have so - far prohibited the wide usage of atomically thin nanopores membranes, most particularly because the process of nanopore formation still lacks a reproducible, scalable and industrially viable fabrication approach. The main goal of this proposal is to - develop and finally commercialize such a membrane with precise array of functional nanopores. In this proposal, based on the knowledge and experience resulting from our ERC project [project no. 335879], we will employ a novel two steps approach based - on organic and supramolecular chemistry to synthesize atomically thin proton exchange membrane bearing a chemically well-defined array of nanopores and we will control the functionality of the nanopore rim by using specific chemical modifications on - the backbones of monomers used to form the high selectivity proton exchange membrane (PEM). If the testing and technical reports are successful, the resulting PEM will be used in DMFC field and other related area, such as desalination and osmosis - electricity generation. - - 2019-03-31, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Netherlands - - - NANOPORE - - - ERC-2017-PoC - - - 780004 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 1 499 756 - - - Harnessing Non-Covalent Interactions for Control of Regioselectivity and Site-Selectivity in Catalysis - - - EUR 1 499 756 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Nature has been employing attractive non-covalent interactions for billions of years to enable the chemical synthesis machinery of life that is enzymatic catalysis. In comparison, synthetic chemists have only very recently - started to employ the very strongest, hydrogen bonds and ion pairs, to control selectivity in synthetic routes. This has occurred predominantly in the rapidly growing of enantioselective organocatalysis and has quickly had a huge impact. The vision - of this grant is to take these insights and apply them to control of two more important aspects of selectivity facing the synthetic chemist – regioselectivity (positional selectivity within a particular functional group) and site-selectivity (within - a wider molecule). These selectivity aspects are particularly relevant due to the increasing number of methods for functionalisation of C-H bonds, in which the overarching challenge is obtaining selectivity for one in the presence of many. - - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - NonCovRegioSiteCat - - - ERC-2017-STG - - - 757381 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 496 730 - - - High-Resolution Imaging and Spectroscopy of Exoplanets - - - EUR 1 496 730 - - - France - France - - - Research Organisations - Research Organisations - - Atmospheric composition provides essential markers of the most fundamental properties of exoplanets, such as their formation mechanism or internal structure. New-generation exoplanet imagers have been designed to achieve high - contrast for the detection of young giant planets in the near-infrared, but they only provide very low spectral resolutions (R<100) for their characterization. For a major breakthrough in the comprehension of young exoplanets and their - atmospheres, an increase of a factor 100 to 1000 in spectral resolution is absolutely required. - - 2022-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - HiRISE - - - ERC-2017-STG - - - 757561 - - - - - TURUN YLIOPISTO - TURUN YLIOPISTO - - - EUR 2 498 606 - - - Ancestral environmental exposures and offspring health – a multigenerational epidemiologic cohort study across 3 generations - - - EUR 2 498 606 - - - Finland - Finland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - MULTIEPIGEN seeks to solve does ancestral exposure to various stressors transmit to offspring via epigenetic mechanisms. Thus far animal models have indicated that exposure to certain stressors can lead to phenotypic changes - not only in the predisposed individuals, but also in the future generations, such that individuals can acquire phenotypes caused by exposures of their ancestors. Such effects do not involve new DNA mutations, but are transmitted to offspring via - epigenetic mechanisms such as the transfer of non-coding RNA molecules in the semen. In humans, intergenerational transmission has been examined extremely little because a priori designed population-based studies across several generations are - lacking. To close this gap MULTIEPIGEN will expand the well-characterized Cardiovascular Risk in Young Finns Study (YFS) to the parents and offspring of the original YFS participants. During the ERC funding period, we will perform field studies - involving N~9000 individuals across 3 generations and test 3 key ancestral exposures with very high plausibility causing intergenerational effects on obesity-related phenotypes, cognitive function and psychological well-being. The studied exposures - are 1) tobacco smoke, 2) persistent organic pollutants, and 3) accumulation of psychosocial adversities. We will collect serum, blood and semen samples for epigenetic marker analysis to provide understanding of the mechanisms of intergenerational - transmission in humans. Specifically, we will seek proof for the hypothesis that paternal stressors can lead to phenotypic changes in the offspring via non-coding RNA molecules in the semen. Multigenerational epidemiologic data showing robust links - between ancestral exposures and offspring phenotypes that operate with biologically plausible epigenetic mechanism would provide a conceptual change in the developmental biology in humans and have substantial ramifications on public health. - - 2022-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Finland - - - MULTIEPIGEN - - - ERC-2016-ADG - - - 742927 - - - - - UNIVERSITE D'AIX MARSEILLE - UNIVERSITE D'AIX MARSEILLE - - - EUR 1 859 656 - - - Horn and Crescent. Connections, Mobility and Exchange between the Horn of Africa and the Middle East in the Middle Ages - - - EUR 1 859 656 - - - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project offers the first comprehensive study of medieval connections between the Horn of Africa and the Middle East in both Christian and Islamic contexts. It pursues the hypothesis that mobility and exchange along trade - and pilgrimage routes, on both sides of and across the Red Sea, were not only vectors for the spread of Islam but also factors of African Christianities’ resiliency and reconfiguration at the same time. Medieval connections of Ethiopian and Nubian - Christianities with other Eastern Christian churches have longer been studied than has been the spread of Islam across the Red Sea or along the Nile valley which remains poorly known. These parallel connections within Christen- and Islamdom across - the same area have never been studied jointly, nor have been Christian-Muslim relations on such a scale. The project ultimately aims to reconnect the Horn of Africa to the global history of the area by connecting disjoint fields of research. - - 2022-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - France - - - HORNEAST - - - ERC-2016-COG - - - 726206 - - - - - UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA - UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA - CONSIGLIO NAZIONALE DELLE RICERCHE - DHITECH DISTRETTO TECNOLOGICO HIGH-TECH SCARL - - - EUR 150 000 - - - A holographic microscope for the immersive exploration of augmented micro-reality - - - EUR 150 000 - - - Italy - Italy - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Virtual reality, augmented reality and mixed reality are beginning to transform the way we explore and acquire information from the macroscopic world around us. At the same time, recent advances in holographic microscopy are - providing new tools for the 3D imaging of physical and biological phenomena occurring at the micron scale. Project ADMIRE will combine this two emerging technologies into the first prototype of an AugmenteD MIcro-REality system for the immersive - exploration and the quantitative analysis of three-dimensional processes at the micron scale. - - 2019-04-30, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Italy - - - ADMIRE - - - ERC-2017-PoC - - - 780333 - - - - - BEN-GURION UNIVERSITY OF THE NEGEV - BEN-GURION UNIVERSITY OF THE NEGEV - - - EUR 1 328 712 - - - Engineering translation machinery to produce light-responsive protein-polymers - - - EUR 1 328 712 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - A general and versatile technology to engineer visible light-responsive biological agents will enable spatio-temporal manipulation and interrogation of proteins, pathways, and cells, and the design of “smart” biomaterials that - can direct and respond to biological processes on-demand. Site specific incorporation of multiple visible-light-responsive chemical groups at the polypeptide level will constitute a universal methodology for precise production of light-responsive - proteins and protein-based materials. However, inadequate engineering of the protein translation apparatus limits the number and complexity of chemical groups that can be incorporated into proteins as synthetic amino acids (sAAs). This limitation - precludes the incorporation of recently discovered visible-light-responsive chemical groups, hinders protein engineering efforts, and excludes production of biomaterials in which multiple identical sAAs provide new physical or biophysical properties. - We propose to overcome this challenge by generating a genomic-engineering based platform for co-evolution of multiple components of the translation machinery (the aminoacyl tRNA synthetase, tRNA, and elongation factor) to select for cellular - machinery capable of multi-site incorporation of highly substituted azobenzenes with a range of biologically relevant photochemical properties. We will then utilize these translation systems to produce libraries of azobenzene-containing protein-based - materials to elucidate the sequence-function requirements for directing light-responsive self-assembly of macromolecular structures, and to generate biomaterial formulations for control of various intra- and extra-cellular processes. By developing - and marrying technologies in synthetic biology, chemistry, and biomaterials, this study will enable the synthesis of light-responsive proteins, deepen our understanding of natural and evolved translation systems, and create new classes of functional - light-responsive biomaterials. - - 2022-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Israel - - - PolControl - - - ERC-2017-STG - - - 756996 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - - - EUR 269 857,80 - - - The workings of metacognition in decision-making - - - EUR 269 857,80 - - - United Kingdom - United States - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Decision-making is one of the most fundamental parts of our daily life. Undoubtedly, when having to select a course of action reflective monitoring and control of our decision process (metacognition) is of crucial importance. - For instance, when a doctor has to make a medical decision, information from different sources are being accrued and combined to form a diagnosis (e.g., information from MRI images and from the anamnesis), but when a doctor is uncertain about the - quality of the decision additional tests can be considered. Despite the importance of effective decision-making in all aspects of life, it’s currently unclear how our metacognitive system operates and how common factors such as sleepiness and - tiredness, well known to induce fragmentation of cognition, influence our metacognitive abilities. In sum, at the moment it remains unclear how and when we are capable of knowing that we know and knowing how we perform. - - 2021-01-01, ongoing project - - - 2018-01-02 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - Meta_Mind - - - H2020-MSCA-IF-2015 - - - 704361 - - - - - UNIVERSITE DE GENEVE - UNIVERSITE DE GENEVE - - - EUR 1 500 000 - - - Three Indirect Probes of Lyman continuum LEakage from galaxies - - - EUR 1 500 000 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Cosmic reionization corresponds to the period in the history of the Universe during which the predominantly neutral intergalactic medium was ionised by the emergence of the first luminous sources. Young stars in primeval - galaxies may be the sources of reionization, if the ionising radiation, called Lyman continuum (LyC), that they produce can escape their interstellar medium: the escape fraction of LyC photons from galaxies is one of the main unknowns of reionization - studies. This ERC project will contribute to answer this question, by computing from simulated galaxies three indirect diagnostics of LyC leakage that were recently reported in the literature, and comparing the virtual observables with the direct - escape of LyC photons from simulated galaxies, and with observations. The first diagnostic for LyC leakage relates the escape of the strongly resonant Lyman-alpha radiation from galaxies to the LyC escape. It was proposed by the PI (Verhamme et al. - 2015), and recently validated by observations (Verhamme et al. 2016). The second diagnostic proposes that the strength of Oxygen lines ratios can trace density-bounded interstellar regions. It was the selection criterion for the successful detection - of 5 strong Lyman Continuum Emitters from our team (Izotov 2016a,b). The third diagnostic relates the metallic absorption line strengths to the porosity of the absorbing interstellar gas in front of the stars. The increasing opacity of the - intergalactic medium with redshift renders direct LyC detections impossible during reionisation. Indirect methods are the only probes of LyC leakage in the distant Universe, and the proposed diagnostics will soon become observables at the redshifts - of interest with JWST. They have passed the validation tests, it is now urgent to calibrate these indicators on state-of-the art simulations of galaxy formation. This is the main objective of the proposed project. - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Switzerland - - - TRIPLE - - - ERC-2017-STG - - - 757258 - - - - - THE UNIVERSITY OF MANCHESTER - FERMI RESEARCH ALLIANCE LLC - - - EUR 251 857,80 - - - Searching for new physics with liquid argon time projection chambers and developing the technology for the future of neutrino physics - - - EUR 251 857,80 - - - United Kingdom - United States - - - Higher or Secondary Education Establishments - Other - - The field of neutrino physics is an exciting one to be involved in at the moment. Neutrinos are the most mysterious fundamental, interacting so weakly with other matter that they are elusive to measurements. They also offer - the only known indicators of physics beyond the Standard Model. I will use this fellowship to build expertise in the technology that will define the future of the field of neutrino physics - the liquid argon time projection chamber (LAr-TPC). I will - spend the outgoing phase at Fermilab, USA, installing and commissioning the SBND detector, and working with data from SBND and the existing MicroBooNE detector. I have a track-record of pioneering searches for new physics, and will continue this by - searching for a new Z boson that could be an explanation for the g-2 anomaly. I will also capitalise on my involvement in the protoDUNE liquid argon test-beam experiment, taking the protoDUNE data and applying it to the SBND and MicroBooNE detector - simulations, to bring a new level of precision to the experiment. I have particular expertise in the reconstruction of low-energy electromagnetic showers. I will combine this expertise with the new protoDUNE data to develop new algorithms to enable - MicroBooNE and SBND to investigate the MiniBooNE low-energy excess and search for sterile neutrinos. In the return year, I will bring my expertise in LAr-TPC technology back to the UK, and take a leading role in setting up a major production site for - making anode planes for the DUNE far detector. - - 2021-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - LARNUEXP - - - H2020-MSCA-IF-2016 - - - 752309 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 974 526 - - - Homotopy Theory of Moduli Spaces - - - EUR 974 526 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Moduli spaces are spaces which describe all mathematical objects of some type. This proposal concerns the study of certain moduli spaces via techniques from homotopy theory, from several different points of view. The main - moduli spaces in which we are interested are moduli spaces of manifolds, or equivalently classifying spaces of diffeomorphism groups of manifolds. We are also interested in spaces of positive scalar curvature metrics on smooth manifolds, which we - study by relating them to moduli spaces of smooth manifolds. - - 2023-09-30, Grant Agreement signed - - - 2018-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - HToMS - - - ERC-2017-STG - - - 756444 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 173 076 - - - Development of a high-performance nanofluidic osmotic diode for efficient voltage-driven desalination and pumping - - - EUR 173 076 - - - France - - - Research Organisations - - Water scarcity is an urgent global challenge and one of the greatest societal threats posed by climate change. Despite growing concern over water availability, processes to expand water supplies beyond current freshwater - reserves, such as desalination and wastewater reclamation, still suffer from insufficient rejection of contaminants and relatively high energy requirements. Nanofluidic technologies have the potential to revolutionize water treatment owing to the - extraordinary transport characteristics of confined pores. The objective of the proposed project is to develop a new nanofluidic device—the osmotic diode—for voltage-driven desalination and pumping. To control water and ion transport, the device - requires a nanopore with tailored asymmetric surface charge. An applied voltage difference can be used to drive water molecules through the nanopore while ions are rejected, desalinating source water. The system is advantageous because permeability - and selectivity properties can be tuned based on nanopore characteristics, and it offers improved versatility compared to existing desalination processes. To realize the technology, the proposed work will (i) fabricate a single pore osmotic diode - with tailored surface charge, (ii) characterize water transport across such a nanopore utilizing ultrasensitive flow measurement techniques, and (iii) use knowledge from the single pore system to scale up performance to many-pored membranes. - Throughout the project, advanced modeling techniques will be utilized to fundamentally understand transport and further optimize the system. The proposed research action will address Horizon 2020 Societal Challenges related to water security and - resource efficiency while advancing the field of nanotechnology through the development of new fabrication and flow measurement methods. The research action will also represent the first proof-of-concept for an osmotic diode system and lay the - foundation for further commercialization of the process. - - - - - - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - France - - - NanoOsmDiode - - - H2020-MSCA-IF-2016 - - - 743637 - - - - - MATERIALISE NV - - - EUR 160 800 - - - Flexible and open-source tool for accurate reconstruction using industrial X-ray computed tomography - - - EUR 160 800 - - - Belgium - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Our ability to achieve breakthroughs in manufacturing is dependent on our capacity to measure the features that define these breakthroughs. In other words, we can manufacture only as well as we can measure. Recent trends - indicate that the future of mass production is in additive manufacturing (AM). X-ray computed tomography (CT) is the optimal solution for quantitative inspection of AM products as it is currently the only technology that can perform non-destructive - measurements of both internal and external features. However, the reliability of CT measurements is not yet established and the application of CT for product inspection is limited to qualitative tasks. FlexCT is a multi-disciplinary research project - that answers the imminent need to bring CT to measurement maturity to keep the pace with the improvements and wider adoption of AM. The fields of dimensional metrology, software engineering, and manufacturing are combined to produce an effective and - open solution for the decisive adoption of CT to inspection of AM and other high-value products. - - - 2019-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-SE - Society and Enterprise panel - - - Belgium - - - FlexCT - - - H2020-MSCA-IF-2016 - - - 752672 - - - - - THE UNIVERSITY OF NOTTINGHAM - THE UNIVERSITY OF NOTTINGHAM - - - EUR 1 971 468 - - - Three-Dimensional Mapping Of a Single Hydrogen Bond - - - EUR 1 971 468 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - All properties of matter are ultimately governed by the forces between single atoms, but our knowledge of interatomic, and intermolecular, potentials is often derived indirectly. - - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - 3DMOSHBOND - - - ERC-2017-STG - - - 757720 - - - - - FORSCHUNGSZENTRUM JULICH GMBH - FORSCHUNGSZENTRUM JULICH GMBH - - - EUR 150 000 - - - Versatile and Innovative Detector for Electron Optics - - - EUR 150 000 - - - Germany - Germany - - - Research Organisations - Research Organisations - - The VIDEO project will professionalize and integrate software and develop open standard file formats for electron microscopy based on results from the ERC Advanced Grant project IMAGINE, supplemented with results and support - from other research groups and hardware vendors. Our goal is to combine these separate activities into an open software platform and to develop open standards, which will enable vendors and users to develop interoperable solutions in this area, and - to explore business and sustainability models. - - 2019-06-30, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Germany - - - VIDEO - - - ERC-2017-PoC - - - 780487 - - - - - UNIVERSITEIT UTRECHT - UNIVERSITEIT UTRECHT - - - EUR 2 205 493,75 - - - Intergroup toleration: It’s Nature, Processes, and Consequences for Culturally Diverse Societies - - - EUR 2 205 493,75 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Increasingly our societies are becoming more diverse and how to live with this diversity is one of the most pressing questions of our time. In Europe, intergroup tolerance has been proposed as a key aspect of living - harmoniously and productively with diversity; it is critical because objection and disagreement about what is good and right are inevitable. A diverse, egalitarian, and peaceful society does not require that we all like each other, but it does - require that people at least tolerate one another. Yet, there has been very little by way of social psychological theorizing and systematic empirical research on intergroup toleration. - - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Netherlands - - - InTo - - - ERC-2016-ADG - - - 740788 - - - - - CHALMERS TEKNISKA HOEGSKOLA AB - CHALMERS TEKNISKA HOEGSKOLA AB - - - EUR 1 499 085 - - - Strong interactions for precision nuclear physics - - - EUR 1 499 085 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Nuclear physics is a cornerstone in our scientific endeavour to understand the universe. Indeed, atomic nuclei bring us closer to study both the stellar explosions in the macrocosmos, where the elements are formed, and the - fundamental symmetries of the microcosmos. Having access to a a precise description of the interactions between protons and neutrons would provide a key to new knowledge across 20 orders of magnitude; from neutrinos to neutron stars. Despite a - century of the finest efforts, a systematic description of strongly interacting matter at low energies is still lacking. Successful theoretical approaches, such as mean-field and shell models, rely on uncontrolled approximations that severely limit - their predictive power in regions where the model has not been adjusted. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Sweden - - - PrecisionNuclei - - - ERC-2017-STG - - - 758027 - - - - - UNIVERSITY OF BRISTOL - - - EUR 183 454,80 - - - Dynamic control of assembly, directonnality and chirality in hydrogen bond networks. - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - By combining biology's information storage and replication strategies, namely specific hydrogen-bonding between nucleobases, with the potential for hydrogen-bond reorganisation in novel 'refoldable foldamers', we propose to - develop a new, artificial but bio-inspired mechanism for the transfer of information in chemical systems. Based on preliminary modelling studies, we will focus on one type of polyurea structures, built from 'Nowick'-style motifs, which spontaneously - fold in solution, forming intramolecular polarized hydrogen-bond networks. Upon addition of simple chemical additives forming competitive intermolecular hydrogen bonds with the foldamer, the directionality of these networks could be modified, - transforming a conformational mixture to a well-defined unidirectional network. Molecular events such as reversible switching, chemical sensing, and long-distance information communication will be studied. Then, biomimetic additives such as - nucleobases will be investigated, and their impact on the folding of the oligomers will be analysed. We will also investigate 3D hydrogen bond networks, which will provide highly functionalised, well-defined macromolecules in a bottom-up approach, - and study the change of macromolecular structure and chirality upon stimulus. Finally, structures that give a non-spectroscopic 'readout' of the interaction with the additive will be built, which for example exhibit 'off-on' fluorescence or 'off-on' - catalytic activity. The application of these foldamers in the construction of photochemically switchable molecular devices will also be investigated. - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - DYNASSEMBLY - - - H2020-MSCA-IF-2016 - - - 745476 - - - - - FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA) - FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA) - - - EUR 1 499 812,50 - - - Hypermutated tumors: insight into genome maintenance and cancer vulnerabilities provided by an extreme burden of somatic mutations - - - EUR 1 499 812,50 - - - Spain - Spain - - - Research Organisations - Research Organisations - - Mutations are the fuel of any evolutionary process, and this also applies to carcinogenesis. The advent of affordable DNA sequencing has enabled mutagenic processes in the human soma to be quantified genome-wide, revealing a - striking occurrence of hypermutated tumors. They exhibit an extreme load of somatic changes, often harbouring hundreds of single-nucleotide variants and/or indels per megabase. The HYPER-INSIGHT project is organized into three objectives, which aim - to take advantage of the unique opportunity provided by genome sequences of hypermutated and ultramutated tumors. In particular, this work planned in this project aims to further our knowledge on (i) the regional organization of the DNA replication - and repair program in human cells, and the determinants thereof, (ii) the extent of selection which acts on somatic variants in various pathways or complexes and (iii) opportunities for selectively targeting DNA repair deficiencies that manifest as - hypermutation. Methodologically, our work will employ a three-pronged approach. First, we will perform a multitude of rigorous statistical analyses that draw on the rich and still-expanding resources provided by cancer genomics consortia. Second, we - will perform exome and genome sequencing, focusing on ultramutated tumors caused by specific defects in the DNA maintenance machinery. Third, the project involves conditional essentiality screens on cancer cell lines with hypermutant backgrounds. - Their goal is to discover synthetic lethality relationships, useful for targeting hypermutating cells, while sparing healthy ones. In summary, one of the promises of cancer genome sequencing projects was to elucidate the mechanisms underlying - mutational processes in the human soma, advancing our understanding of this important facet of cancer biology. We will work towards realizing this promise, thereby strengthening the EU’s position in the global scientific endeavour. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Spain - - - HYPER-INSIGHT - - - ERC-2017-STG - - - 757700 - - - - - UNIVERSITE DE NAMUR ASBL - UNIVERSITE DE NAMUR ASBL - - - EUR 150 000 - - - CANITEST: Proof-Of-Concept of a PCR test designed to identify the dogs carrying the more virulent strains of Capnocytophaga canimorsus - - - EUR 150 000 - - - Belgium - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The idea to be taken as proof of concept is drawn from the ERC Advanced grant N°293605-CAPCAN (2012-2016). This grant aimed at understanding the molecular and genetic bases of the dramatic human infections caused by - Capnocytophaga canimorsus. One of the questions that we addressed in the frame of CAPCAN is why are there so few cases of human infections while so many dogs carry C. canimorsus? In other words, are all C. canimorsus strains equally dangerous and, if - not, could we prevent the disease by detecting the dogs carrying the more dangerous strains? During CAPCAN, among others, we showed that C. canimorsus is endowed with a capsular polysaccharide (CPS) and its assembly pathway was characterized [1]. We - also showed that the CPS of 25/25 strains isolated from human infections present a limited variability, with 3 dominant capsular serovars. In contrast, only 4 out of 52 C. canimorsus isolated from dog mouths did belong to these three serovars [2]. - This implies that a small minority of dog-hosted C. canimorsus strains are virulent for humans than most strains and that these strains can be identified by capsular serotyping. We also set up a PCR test to achieve this capsular serotyping [2]. The - proposal to be taken to proof of concept is to market the PCR test designed to identify the dogs carrying the more virulent strains of C. canimorsus. - - 2019-05-31, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Belgium - - - CANITEST - - - ERC-2017-PoC - - - 780540 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 439 893 - - - Ant navigation: how complex behaviours emerge from mini-brains in interaction with their natural habitats - - - EUR 1 439 893 - - - France - France - - - Research Organisations - Research Organisations - - Navigation is one of the most crucial and most challenging problems animals face. Behavioural analyses have shown that animals make use of a number of different mechanisms to navigate, but very little is known of how spatial - information is processed and integrated by the brain. This project will exploit the stunning ability of ants in learning long visual routes to investigate the mechanisms of navigation in a brain numerically much simpler than vertebrate. We will - combine an ecological approach with state-of-the-art technologies to enable a thorough control of sensory-motor cues while the ant is navigating in virtual-reality reconstructions of its natural environments. This new and powerful method will enable - us to dissect the mechanisms underlying the emergence of navigational behaviours by performing straightforward manipulations. The results will be modelled in the light of insect neurobiology and integrated into an increasingly complete neural - architecture. This neural architecture will be embedded into an agent navigating in the same virtual-reality environment as the real ants for testing. The advantage of such an inter-disciplinary approach is that failures of our agent will help us - identify gaps in our knowledge and thus fuel new experimentation. Reciprocally, our agent will become increasingly refined in the light of incoming experimental results. This will create a positive feedback towards a complete, multi-level - understanding of navigation in the wild. The findings will inspire new robust solutions for navigational problems that can be applied to bio-robotics. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - EMERG-ANT - - - ERC-2017-STG - - - 759817 - - - - - UNIVERSITA DEGLI STUDI DI TRENTO - UNIVERSITA DEGLI STUDI DI TRENTO - - - EUR 1 491 479 - - - Accurate and Scalable Processing of Big Data in Earth Observation - - - EUR 1 491 479 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - During the last decade, a huge number of earth observation (EO) satellites with optical and Synthetic Aperture Radar sensors onboard have been launched and advances in satellite systems have increased the amount, variety and - spatial/spectral resolution of EO data. This has led to massive EO data archives with huge amount of remote sensing (RS) images, from which mining and retrieving useful information are challenging. In view of that, content based image retrieval - (CBIR) has attracted great attention in the RS community. However, existing RS CBIR systems have limitations on: i) characterization of high-level semantic content and spectral information present in RS images, and ii) large-scale RS CBIR problems - since their search mechanism is time-demanding and not scalable in operational applications. The BigEarth project aims to develop highly innovative feature extraction and content based retrieval methods and tools for RS images, which can - significantly improve the state-of-the-art both in the theory and in the tools currently available. To this end, very important scientific and practical problems will be addressed by focusing on the main challenges of Big EO data on RS image - characterization, indexing and search from massive archives. In particular, novel methods and tools will be developed, aiming to: 1) characterize and exploit high level semantic content and spectral information present in RS images; 2) extract - features directly from the compressed RS images; 3) achieve accurate and scalable RS image indexing and retrieval; and 4) integrate feature representations of different RS image sources into a unified form of feature representation. Moreover, a - benchmark archive with high amount of multi-source RS images will be constructed. From an application point of view, the developed methodologies and tools will have a significant impact on many EO data applications, such as accurate and scalable - retrieval of: specific man-made structures and burned forest areas. - - 2023-03-31, Grant Agreement signed - - - 2018-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Italy - - - BigEarth - - - ERC-2017-STG - - - 759764 - - - - - ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM - ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM - UNIVERSITEIT LEIDEN - - - EUR 150 000 - - - Triple negative breast cancer control through synergistic inhibition of EGFR and CDK9 signaling - - - EUR 150 000 - - - Netherlands - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Triple negative breast cancer (TNBC) is an aggressive disease, accounting for 15-20% of breast cancer cases, but disproportionally causing breast cancer-related death. TNBC does not express the targetable receptors ER, PR, and - HER2 that are known to drive other forms of breast cancer. Mainstay practice for TNBC in the clinic is to treat with non-targeted cytotoxic chemotherapies. Long-term outcomes are however still poor, most likely owing to intrinsic drug resistance. - Clinical trials have attempted to explore molecular targeted therapies to block dysregulated growth factor receptors in TNBC, for instance, epidermal growth factor receptor (EGFR), as it is overexpressed in ~80% of TNBC. Yet, giving the long-standing - availability of clinically approved EGFR-targeted therapies, such as lapatinib, the clinical benefit of single agent therapy is unsatisfactory, owing to the compensatory dysregulated signaling pathways. In our ongoing ERC – Advanced Grant Triple-BC - (#322737) we are striving to explore combinatorial molecular targeted therapies to concomitantly block the identified dysregulated signaling pathways. Our preliminary work revealed that an inhibitor targeting cyclin-dependent kinase 9 (CDK9) - strikingly synergized with targeting EGFR receptor family signaling to inhibit cell proliferation of TNBC cell lines. The overall goal of this PoC project is to exploit this novel finding and provide proof-of-concept evidence that stalling CDK9 - signaling may enable successful targeted combination therapy in TNBC. Therefore, the specific objective is to assess the pharmacological response of dual EGFR-CDK9 targeting in TNBC patient-derived xenograft (PDX) mouse models in vivo. We envisage - that this PoC project will translate our identified successful synergistic treatment into an effective future novel and safe combinatorial targeting strategy benefiting TNBC patients. - - 2018-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Netherlands - - - TRIPLECON - - - ERC-2017-PoC - - - 767854 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 1 496 687 - - - Algorithmic Verification of String Manipulating Programs - - - EUR 1 496 687 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - String is among the most fundamental and commonly used data types in virtually all modern programming languages, especially with the rapidly growing popularity of scripting languages (e.g. JavaScript and Python). Programs - written in such languages tend to perform heavy string manipulations, which are complex to reason about and could easily lead to programming mistakes. In some cases, such mistakes could have serious consequences, e.g., in the case of client-side web - applications, cross-site scripting (XSS) attacks that could lead to a security breach by a malicious user. - - 2022-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - AV-SMP - - - ERC-2017-STG - - - 759969 - - - - - UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA - UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA - - - EUR 1 494 662 - - - How natural hand usage shapes behavior and intrinsic and task-evoked brain activity. - - - EUR 1 494 662 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - A seminal concept in modern neuroscience is the plasticity of the developing and adult brain that underpins the organismic ability to adapt to the ever-changing environment and internal states. Conversely, recent studies - indicate that ongoing sensory input seems not crucial to modulate the overall level of brain activity, which instead it is strongly determined by its intrinsic fluctuations. These observations raise a fundamental question: what is coded in the - intrinsic activity? This project tests the hypothesis that intrinsic activity represents and maintains an internal model of the environment built through the integration of information from visual and bodily inputs. The bodily inputs represent the - physical and functional interaction that our body establishes with the external environment. In this framework, the hand has a special role, as it represents the primary means of interaction with the environment. - - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Italy - - - HANDmade - - - ERC-2017-STG - - - 759651 - - - - - FUNDACIO PRIVADA INSTITUT CATALA D'INVESTIGACIO QUIMICA - AICURIS ANTI-INFECTIVE CURES GMBH - - - EUR 743 618,88 - - - Enabling Technologies and Drug Discovery: Continuous Flow Processes to Discover Novel Antiviral Inhibitors - - - EUR 743 618,88 - - - Spain - Germany - - - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - VIRO-FLOW project aims to integrate the advantages of continuous flow chemistry with in vitro microfluidic bioassay technologies for the fast and efficient discovery of novel and innovative inhibitors of the Hepatitis B Virus - (HBV). This programme aims to contribute to the development of innovative methodologies that allow more efficient production of new compounds with anti-viral activity, specifically against HBV, for future transfer of technology and knowledge between - different sectors with relevant economic impact. The global objective of this ITN-EID programme is to provide an innovative and high-level training in drug discovery and enabling technologies for 3 Early-Stage Researchers (ESRs), supported by a - network of experts in anti-infective therapeutics, specifically virology and bacteriology in AiCuris, a pharmaceutical company; and the Institute of Chemical Research of Catalonia (ICIQ), a research Institute focused on sustainable chemistry in the - field of catalysis and flow chemistry (through its technology development unit ERTFLOW). This ITN will educate the next generation of well-prepared ESRs, providing them with the skills necessary to pursue successful careers in a rapidly emerging - field that requires novel multidisciplinary technological development as well as it will also be the channel for educating well-trained researchers with the scientific, technical and entrepreneurial skills so highly needed in the drug discovery - field. - - 2021-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-EID - European Industrial Doctorates - - - Spain - - - VIRO-FLOW - - - H2020-MSCA-ITN-2017 - - - 766058 - - - - - UNIVERSITY OF GLASGOW - UNIVERSITY OF GLASGOW - - - EUR 1 490 050 - - - Computing the Face Syntax of Social Communication - - - EUR 1 490 050 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Social interactions are critical to all societies. One of the most powerful tools for social interaction is the face – a complex system comprising variations of movement (expressions), morphology (shape/structure) and - complexion (color/texture). Consequently, the face can elicit myriad rapid social judgments (e.g. personality, emotion, group membership, age, health, social status) with significant consequences (e.g. sentencing/voting decisions, social isolation, - job offers). Yet, little is known about how the complex, dynamic face transmits the myriad messages that regulate social interactions in different cultures, how these complex face signals map onto psychological processes (e.g. categorical/dimensional - perception) or which signals facilitate or hinder cross-culture communication. This is largely due to fragmented research on social concepts (mental states, personality, emotions), face signals (morphology, movements, complexion) and culture, which, - consequently, has overlooked a possible latent algebraic, syntactical structure to social face signals across cultures. My own work hints at such a structure. My ambitious program will unify these fragments to derive the first generative, algebraic - and syntactical model of social face signals using innovative methods combining social/cultural psychology, 3D dynamic computer graphics, vision science psychophysical methods, and mathematical psychology. It will thus test and validate a new - theoretical framework of social face signals that will unite both categorical/dimensional and universal/culture-specific accounts of social face perception. This framework is highly relevant in the context of globalization and cultural integration - where social communication using virtual agents is integral to modern society. It is thus imperative to equip digital agents with the tools to flexibly generate socially and culturally sophisticated face signals. FACESYNTAX will thus transfer the - generative model to social robotics. - - 2023-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - FACESYNTAX - - - ERC-2017-STG - - - 759796 - - - - - POLITECHNIKA POZNANSKA - POLITECHNIKA POZNANSKA - - - EUR 1 385 000 - - - 'If immortality unveil…'– development of the novel types of energy storage systems with excellent long-term performance - - - EUR 1 385 000 - - - Poland - Poland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The major goal of the project is to develop a novel type of an electrochemical capacitor with high specific power (up to 5 kW/kg) and energy (up to 20 Wh/kg) preserved along at least 50 000 cycles. Thus, completion of the - project will result in remarkable enhancement of specific energy, power and life time of modern electrochemical capacitors. Advanced electrochemical testing (galvanostatic cycling with constant power loads, electrochemical impedance spectroscopy, - accelerated aging and kinetic tests) will be accompanied by materials design and detailed characterization. Moreover, the project aims at the implementation of novel concepts of the electrolytes and designing of new operando technique for capacitor - characterization. All these efforts aim at the development of sustainable and efficient energy conversion and storage system. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Poland - - - IMMOCAP - - - ERC-2017-STG - - - 759603 - - - - - ACADEMISCH ZIEKENHUIS LEIDEN - ACADEMISCH ZIEKENHUIS LEIDEN - - - EUR 1 499 850 - - - Protein nano-patterning using DNA nanotechnology; control of surface-based immune system activation - - - EUR 1 499 850 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Protein nanopatterning concerns the geometric arrangement of individual proteins with nanometre accuracy. It is becoming apparent that protein nanopatterns are essential for cellular function, and have roles in cell signalling - and protection, phagocytosis and stem cell differentiation. Recent research indicates that our immune system is activated by nanopatterned antibody platforms, which initiate the classical Complement pathway by binding to the first component of - Complement, the C1 complex. DNA nanotechnology can be used to form self-assembled nanoscale structures, which are ideal for use as templates to pattern proteins with specific geometries and nanometre accuracy. I propose to use DNA to nanopattern - antigens and agonistic aptamers with defined geometry to study and control Complement pathway activation by the C1 complex. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - BioNanoPattern - - - ERC-2017-STG - - - 759517 - - - - - UNIVERSITY OF BRISTOL - UNIVERSITY OF BRISTOL - - - EUR 952 561 - - - Soft Water: understanding what makes a fluid behave like water - - - EUR 952 561 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Water is the most common and yet least understood material on Earth. Despite its simplicity, the structure of the water molecule is responsible for a vast array of properties that are unlike those of other fluids. Water - anomalies, like the density maximum at 4 degrees Celsius, play a fundamental role in determining the Earth's climate, and ultimately the very existence of life. From an anthropic viewpoint, the properties of water are as if they were fine-tuned. It - is this uniqueness that hinders our understanding of how water behaves in many natural systems and technological applications; for example, our inability to predict the stability limit of water in supercooled clouds, and the rates of ice - crystallization, is credited as being one of the biggest unknowns in models of Climate Change, where the scattering of energy from suspended ice droplets in the clouds plays a central role in determining Earth's radiation budget. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - SOFTWATER - - - ERC-2017-STG - - - 759187 - - - - - HELMHOLTZ ZENTRUM POTSDAM DEUTSCHESGEOFORSCHUNGSZENTRUM GFZ - HELMHOLTZ ZENTRUM POTSDAM DEUTSCHESGEOFORSCHUNGSZENTRUM GFZ - - - EUR 1 499 308 - - - Climate Sensitivity of Glacial Landscape Dynamics - - - EUR 1 499 308 - - - Germany - Germany - - - Research Organisations - Research Organisations - - How do erosion rates in glacial landscapes vary with climate change and how do such changes affect the dynamics of mountain glaciers? Providing quantitative constraints towards this question is the main objective of COLD. - These constraints are so important because mountain glaciers are sensitive to climate change and their deposits provide a unique history of Earths terrestrial climate that allows reconstructing leads and lags in the climate system. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - COLD - - - ERC-2017-STG - - - 759639 - - - - - TECHNISCHE UNIVERSITAET MUENCHEN - TECHNISCHE UNIVERSITAET MUENCHEN - - - EUR 1 366 875 - - - Demystifying the Quark-Gluon Plasma - - - EUR 1 366 875 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The primary objective of this project is to explore the properties of a new state of matter, the Quark-Gluon Plasma (QGP), at the highest energies to date. The QGP consists of asymptotically free quarks and gluons and the - evidence for its discovery was announced in experiments analyzing collisions of heavy ions. Previous experiments at lower energies have caused a dramatic change of paradigm in our understanding - measurements at Relativistic Heavy Ion Collider showed - that the QGP behaves like a strongly coupled liquid, instead of the weakly interacting gas expected by theorists. The focus of this project is the measurement of the anisotropic flow, which has proven to be the most informative probe for studying the - properties of nuclear matter produced in heavy-ion collisions. The analysis methods to be utilized are multiparticle correlation techniques developed by the PI. Currently mainly the first moments (averages) of multiparticle correlations are used. - Within the scope of the theoretical subproject we aim to derive analytic expressions for higher order moments of multiparticle correlations by continuing a pioneering work recently initiated by the PI. The here proposed project aims also the - measurement of new flow observables, so-called Symmetric Cumulants, recently introduced in the field by PI. The recent restart of Large Hadron Collider at top energy, a record breaking 5.02 TeV center of mass energy, offers a truly unique and a - timely opportunity for this project. The main dataset will comprise the heavy-ion collisions collected with ALICE detector at the Large Hadron Collider. Collisions of smaller systems will be scrutinized as well in order to determine the onset of QGP - formation. This project offers a unique opportunity to pin down quantitatively the properties of the QGP, beyond the rather qualitative analyses that are currently carried out in the field. It also will impact the fields of high energy physics, - nuclear physics, cosmology and hydrodynamics. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - QGP-MYSTERY - - - ERC-2017-STG - - - 759257 - - - - - TECHNISCHE UNIVERSITEIT DELFT - TECHNISCHE UNIVERSITEIT DELFT - - - EUR 1 500 000 - - - Constructing polar rotors in metal-organic frameworks for memories and energy harvesting - - - EUR 1 500 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - I seek to develop new ferroelectrics based on metal-organic frameworks with dipolar rotors. Ferroelectrics are targeted to be used as physically flexible memories and mechanical energy harvesters for biocompatible sensors and - implantable monitoring devices. - - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - MemoMOFEnergy - - - ERC-2017-STG - - - 759212 - - - - - STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN - STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN - - - EUR 1 500 000 - - - Topological phononics through nano-optomechanical interactions - - - EUR 1 500 000 - - - Netherlands - Netherlands - - - Research Organisations - Research Organisations - - The concept of topology has proven very powerful in predicting and explaining a range of intriguing phenomena for the behaviour of electrons in solid-state materials, including the existence of topological phases that offer - robust transport with unusual characteristics. This program aims to create and study topological behaviour for sound in systems that couple light and mechanical motion through radiation pressure. I will realize on-chip nano-optomechanical systems - where many optical and mechanical modes interact. Through this interaction, suitable laser illumination will induce phononic transport with properties that are not found in any natural material. In particular, they will establish topologically - nontrivial acoustic phases that we will create and explore in space and time using a new optical measurement technique. The induced behaviour crucially depends on the extreme coupling between optical fields and nanomechanical resonators when both are - confined at the nanoscale. I aim to study three manifestations of topological behaviour: (1) The creation of an acoustic quantum Hall phase, in which topologically protected unidirectional sound propagation should emerge, in edge modes that are - robust against disorder. (2) The formation of a new type of topological insulator arising from optomechanical nonlinearity, supporting topological acoustic solitons with unusual dynamics. (3) The breaking of parity-time symmetry in mechanical systems - that undergo both optical damping and amplification, a phase transition with unique topological properties. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - TOPP - - - ERC-2017-STG - - - 759644 - - - - - UNIVERSITA DEGLI STUDI DI PADOVA - UNIVERSITA DEGLI STUDI DI PADOVA - - - EUR 1 446 250 - - - Microbioreactor platforms as in vivo-like systems to probe the role of Neuroblastoma-derived Exosomes in cancer dissemination - - - EUR 1 446 250 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Engineers can actively contribute to fields thought to be out of their “comfort zones”. We can be leaders of discoveries that translate into advances in the understanding of disease and improving human health. Engineers might - use different language and tools than Life Sciences Scientists but we find a common ground, as the laws of Thermodynamics, Physics, and Mathematics also apply to biological phenomena. - - 2022-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Italy - - - MICRONEX - - - ERC-2017-STG - - - 759467 - - - - - BAYERISCHE JULIUS-MAXIMILIANS UNIVERSITAT WURZBURG - BAYERISCHE JULIUS-MAXIMILIANS UNIVERSITAT WURZBURG - - - EUR 1 497 905 - - - Targeting the Oncogenic Function of Myc in vivo - - - EUR 1 497 905 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The transcription factor Myc plays a central role in tumourigenesis but was deemed undruggable due to it being an essential protein. However, recent proof-of-principle studies in mice using a dominant negative allele of Myc - demonstrated the dependency of established tumours on Myc function and showed that mice tolerated Myc inhibition to a degree that allowed tumour regression. In line with these observations my group found Myc to regulate distinct sets of genes at low, - physiological and high, oncogenic levels, because promoters differ in their affinity for Myc. This notion implies the compelling possibility to specifically target the oncogenic functions of Myc. - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - TarMyc - - - ERC-2017-STG - - - 759139 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 498 368 - - - The Graeco-Egyptian State: Hellenistic Archives from Egyptian Mummies - - - EUR 1 498 368 - - - France - France - - - Research Organisations - Research Organisations - - The aim of GESHAEM is to investigate economy, fiscality and territorial management in the most important agricultural region of Egypt, the Fayyum, in the first century of the Greek domination (3rd century BCE). For this - purpose, a large corpus of administrative and fiscal papyri discovered in Egyptian mummies will be studied: the unpublished Greek and Egyptian papyri of the Jouguet collection of the Sorbonne. Coming from bilingual archives, these documents will - change our view of the early Ptolemaic kingdom in the third century BCE. The history of this Hellenistic kingdom has long been described as the history of a Greek kingdom. Recently, however, the native Egyptian contribution in the building of this - kingdom has come to the fore: the Ptolemaic administration was in large part made up of people of Egyptian origin who spoke and wrote both Greek and Egyptian, continuing a millennia-old administrative tradition adapted to the new regime. The Jouguet - papyri open new perspectives because, unlike most demotic documents of the Graeco-Roman period, these were not written inside temples but for the civil government. Like the Greek ones they are concerned with the agricultural administration of the - Fayyum region. The Jouguet texts were written on second-hand papyrus reused to make mummy casing called cartonnage. Most of these decorated mummy cartonnages were destroyed immediately after their discovery at the beginning of the 20th century, but - around twenty remain in part of the Jouguet collection that has not yet been inventoried. The extraction of new papyri from the remaining cartonnages will be achieved without destroying the objects themselves, which will be restored and, for the - first time, studied in their own right. Thus GESHAEM intends to bring new data both for historians working on the ancient economy and fiscality, as well as for art historians. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - GESHAEM - - - ERC-2017-STG - - - 758907 - - - - - UNIVERSITE DE NAMUR ASBL - UNIVERSITE DE NAMUR ASBL - - - EUR 1 499 313 - - - Women in Africa - - - EUR 1 499 313 - - - Belgium - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Rates of domestic violence and the relative risk of premature death for women are higher in sub-Saharan Africa than in any other region. Yet we know remarkably little about the economic forces, incentives and constraints that - drive discrimination against women in this region, making it hard to identify policy levers to address the problem. This project will help fill this gap. - - - 2023-07-31, Grant Agreement signed - - - 2018-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Belgium - - - AfricanWomen - - - ERC-2017-STG - - - 759294 - - - - - UNIVERSITY COLLEGE LONDON - UNIVERSITY COLLEGE LONDON - - - EUR 1 500 000 - - - Deciphering super-Earths using Artificial Intelligence - - - EUR 1 500 000 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The discovery of extrasolar planets - i.e. planets orbiting other stars - has fundamentally transformed our understanding of planets, solar systems and our place in the Milky Way. Recent discoveries have shown that planets - between 1-2 R are the most abundant in our galaxy, so called super-Earths. Yet, they are entirely absent from our own solar system. Their nature, chemistry, formation histories or climate remain very much a mystery. Estimates of their densities - suggest a variety of possible planet types and formation/evolution scenarios but current degeneracies cannot be broken with mass/radius measures alone. Spectroscopy of their atmospheres can provide vital insight. Recently, the first atmosphere around - a super-Earth, 55 Cnc e, was discovered, showcasing that these worlds are far more complex than simple densities allow us to constrain. - - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - ExoAI - - - ERC-2017-STG - - - 758892 - - - - - UNIVERSITE LYON 1 CLAUDE BERNARD - UNIVERSITE LYON 1 CLAUDE BERNARD - - - EUR 1 500 000 - - - Quantum optomechanics at ROOm Temperature - - - EUR 1 500 000 - - - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - 5 years ago, the field of optomechanics has entered the quantum regime. By doing so, this domain which investigates the reciprocal interactions between light and mechanical motion has overcome the long-standing paradox of - Quantum Mechanical effects at the macroscopic scale. Such outstanding achievement relies on the so-called “cavity nano-optomechanical” technology, which combines strongly reduced dimensions with ultra-high optical confinement, enabling very large - optomechanical coupling rates at the nanoscale. - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - Q-ROOT - - - ERC-2017-STG - - - 758794 - - - - - BILKENT UNIVERSITESI VAKIF - BILKENT UNIVERSITESI VAKIF - - - EUR 1 500 000 - - - Resonant Electromagnetic Microscopy: Imaging Cells Electronically - - - EUR 1 500 000 - - - Turkey - Turkey - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Microfluidics technology has been quite successful in fabricating small, low-cost devices with excellent analyte handling capabilities. However, the main detection paradigm in microfluidics has still been optical microscopy — - which is a bulky and expensive technique. A chip-scale detection scheme that can provide multidimensional information is much needed for the widespread adoption of lab-on-a-chip technology. So far, successful capacitive and resonant electrical - sensors have been deployed in the field; yet the focus of these sensors has been to obtain the electrical volume or location of a particle — which constitutes only a limited piece of information about the analytes. Here we propose to redesign and - utilize resonant electrical sensors in a radically different way to obtain images of cells in a microfluidic channel. The technique proposed can also multiplex on-chip cytometry greatly, accomplish low-cost and high-throughput single-cell - transit-time characterization, obtain not only the electrical but also the geometrical size of analytes, determine the dielectric permittivity of analytes, in addition to capturing 1D profile or 2D images of cells. At the basic science level, the - project will enhance our understanding of the interaction of electromagnetic fields and living matter at the single cell level and may provide new insights on cell motility, growth and mechanics. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Turkey - - - REM - - - ERC-2017-STG - - - 758769 - - - - - UNIVERSITATEA POLITEHNICA DIN BUCURESTI - UNIVERSITATEA POLITEHNICA DIN BUCURESTI - - - EUR 1 325 000 - - - Provably Correct Networks - - - EUR 1 325 000 - - - Romania - Romania - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Networks are the backbone of our society, but configuring them is error-prone and tedious: misconfigured networks result in headline grabbing network outages that affect many users and hurt company revenues while security - breaches that endanger millions of customers. There are currently no guarantees that deployed networks correctly implement their operator’s policy. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Romania - - - CORNET - - - ERC-2017-STG - - - 758815 - - - - - UNIVERSITY OF BRISTOL - UNIVERSITY OF BRISTOL - - - EUR 1 712 581 - - - Stimulated Brillouin Scattering based RF to Optical Signal Transduction and Amplification - - - EUR 1 712 581 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - While the detection of weak signals (down to the single photon level) in the optical frequency range is routine on account of the high photon energy (compared to thermal excitation energy kBT) and the availability of efficient - detectors, this is not the case in the radio frequency (RF) and microwave frequency regimes wherein thermal (Johnson) noise in detectors swamps out the faint RF signals (in applications from radio astronomy, MRI to radar) and requires the use of - cryogenic amplifiers. The ability to map signals efficiently from the microwave to optical regime becomes paramount for distant systems to communicate with each other using low loss telecom fibers. Both classical (radio over fiber systems) and - quantum (linking two superconducting qubit processors in two dilution fridges) information processing systems will benefit greatly from the development of an efficient RF to optical signal transducer. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - SBS3-5 - - - ERC-2017-STG - - - 758843 - - - - - CHALMERS TEKNISKA HOEGSKOLA AB - CHALMERS TEKNISKA HOEGSKOLA AB - OMNISYS INSTRUMENTS AB - - - EUR 150 000 - - - TeraHertz quasiOptical Receiver - - - EUR 150 000 - - - Sweden - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Remote sensing and monitoring in various environments solves many scientific and societal problems. Examples are: industrial air pollution control, global atmosphere surveillance, our planet system and the universe - exploration, process controls in industry, and material research in laboratories. Molecular absorption/emission feature, combined with a high penetration depth of THz waves through dust, short wavelength allowing for high pointing directivity, all - these factors determine the uniqueness of the THz range of electro-magnetic wave spectrum (0.1-10THz) in the mentioned applications. High radiometric sensitivity of THz wave detectors is a vital selection criterion for a THz system to become - attractive. Uncooled THz detectors/mixers show adequate sensitivity only for frequencies below 1THz, whereas “supra-THz” (>1THz) detectors require cooling down to 4K. This limitation hinders exploitation of THz spectroscopy for such important - application as atmosphere monitoring, local and global pollution surveillance, security, as well as universal sciences, in full. Small-scale satellites, balloons, portable sensors, can’t afford LHe cooling or power thirsty 4K cryo-coolers. For - large-scale space missions, 4K cooling has already been utilized (e.g. Herschel and Planck Space observatories, COBE, etc), however it limited the missions lifetime significantly. - - - 2019-04-30, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Sweden - - - THOR - - - ERC-2017-PoC - - - 780170 - - - - - ECOLE POLYTECHNIQUE - ECOLE POLYTECHNIQUE - - - EUR 1 499 845 - - - Exploring Relations in Structured Data with Functional Maps - - - EUR 1 499 845 - - - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - We propose to lay the theoretical foundations and design efficient computational methods for analyzing, quantifying and exploring relations and variability in structured data sets, such as collections of geometric shapes, - point clouds, and large networks or graphs, among others. Unlike existing methods that are tied and often limited to the underlying data representation, our goal is to design a unified framework in which variability can be processed in a way that is - largely agnostic to the underlying data type. - - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - EXPROTEA - - - ERC-2017-STG - - - 758800 - - - - - OSLO UNIVERSITETSSYKEHUS HF - OSLO UNIVERSITETSSYKEHUS HF - - - EUR 1 499 638 - - - Imaging Perfusion Restrictions from Extracellular Solid Stress - - - EUR 1 499 638 - - - Norway - Norway - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Even the perfect cancer drug must reach its target to have an effect. The ImPRESS project main objective is to develop a novel imaging paradigm coined Restricted Perfusion Imaging (RPI) to reveal - for the first time in humans - - vascular restrictions in solid cancers caused by mechanical solid stress, and use RPI to demonstrate that alleviating this force will repair the cancerous microenvironment and improve therapeutic response. Delivery of anti-cancer drugs to the tumor - is critically dependent on a functional vascular bed. Developing biomarkers that can measure how mechanical forces in a solid tumor impair perfusion and promotes therapy resistance is essential for treatment of disease. - - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Norway - - - ImPRESS - - - ERC-2017-STG - - - 758657 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 056 664 - - - Correlated frontiers of many-body quantum mathematics and condensed matter physics - - - EUR 1 056 664 - - - France - France - - - Research Organisations - Research Organisations - - One of the main challenges in condensed matter physics is to understand strongly correlated quantum systems. Our purpose is to approach this issue from the point of view of rigorous mathematical analysis. The goals are - twofold: develop a mathematical framework applicable to physically relevant scenarii, take inspiration from the physics to introduce new topics in mathematics. The scope of the proposal thus goes from physically oriented questions (theoretical - description and modelization of physical systems) to analytical ones (rigorous derivation and analysis of reduced models) in several cases where strong correlations play the key role. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - CORFRONMAT - - - ERC-2017-STG - - - 758620 - - - - - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - - - EUR 1 785 195 - - - Nanostructured catalyst overcoats for renewable chemical production from biomass - - - EUR 1 785 195 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In the CATACOAT project, we will develop layer-by-layer solution-processed catalyst overcoating methods, which will result in catalysts that have both targeted and broad impacts. We will produce highly active, stable and - selective catalysts for the upgrading of lignin – the largest natural source of aromatic chemicals – into commodity chemicals, which will have an important targeted impact. The broader impact of our work will lie in the production of catalytic - materials with unprecedented control over the active site architecture. - - 2022-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Switzerland - - - CATACOAT - - - ERC-2017-STG - - - 758653 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 497 996 - - - Innovative Strategies for Unprecedented Remote C-H bond Functionalization by Catalysis - - - EUR 1 497 996 - - - France - France - - - Research Organisations - Research Organisations - - Over the last years, the landscape of the organic chemistry has been reshaped with impressive advances made in the transition metal-catalyzed carbon-hydrogen (C-H) bond functionalization field. Indeed, the functionalization of - building blocks that do not display a reactive functional group but only a simple C-H bond is attractive as it avoids time-consuming and expensive prefunctionalization steps and limits the generation of waste. However, as energies required to break - C-H bonds are similar, the differentiation between two C-H bonds and the selective functionalization of only one of them remain a key challenge. Therefore, the available approaches are still unsatisfactory due to important limitations: low - reactivity, limited scopes and selectivity issues. In this proposal, a general approach to functionalize a CH bond located at a Far position (from a functional group) by Catalysis (FarCatCH) will be implemented with a special focus on underexplored - transformations, affording important sulfur-and fluorine-containing compounds. Herein, I will develop new synthetic approaches for the remote functionalization of molecules based on i) a substrate-selectivity control and ii) the design of new - catalysts using supramolecular tools. I will then iii) address a longstanding reactivity issue in organic synthesis: the trifluoromethylation of aliphatic compounds and apply the supramolecular catalysts for a remote enantioselective transformation. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - FarCatCH - - - ERC-2017-STG - - - 758710 - - - - - UNIVERSITA DEGLI STUDI DI PADOVA - UNIVERSITA DEGLI STUDI DI PADOVA - - - EUR 1 452 210 - - - Republics on the Stage of Kings. Representing Republican State Power in the Europe of Absolute Monarchies (late 16th - early 18th century) - - - EUR 1 452 210 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - RISK investigates Republican pageantry and encomiastic production from late 16th- to early 18th-century Europe, with regard to the Italian city-states that maintained their independence throughout this timeframe (Venice, - Genoa, Lucca), the Republic of Ragusa (today in southernmost Croatia) and the Dutch Republic. A multidisciplinary corpus of sources is taken into account, including: praising texts celebrating Republican values; paintings and engravings displaying - civic rituals, or portraying mythological prosopopoeias of the Republic; and written accounts of public ceremonies, such as the election of the Doge or the triumph performed after a victorious campaign. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Italy - - - RISK - - - ERC-2017-STG - - - 758450 - - - - - UNIVERSITA DEGLI STUDI DI TRENTO - UNIVERSITA DEGLI STUDI DI TRENTO - - - EUR 1 339 351 - - - VAriable ResolutIon Algorithms for macroMOLecular Simulation - - - EUR 1 339 351 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Within the broad spectrum of biological soft matter systems, large proteins and protein assemblies occupy a central role. These molecules are extremely versatile: they can catalyze chemical reactions, transport atoms and - molecules across the cellular membrane, bind to foreign bodies to be destroyed, or combine into large molecular machines that perform a variety of different tasks. One of the most prominent problems in the computational study of these macromolecules - is that the cost of using accurate atomistic models dramatically increases with system size. Simplified, coarse-grained representations offer an elegant and effective alternative to high-resolution models, and enable the simulation of large systems - over extended time scales; the other side of the coin, however, is that the missing chemical detail often represents an insurmountable limitation to the realistic reproduction of the properties of interest. The main goal of the VARIAMOLS project is - to develop and apply novel computer-aided methods for the study of large molecular assemblies and their dynamics, thus bridging the existing gap between computational cost and chemical accuracy. Specifically, the research will unfold along two - intertwined lines: 1) the development of non-uniform resolution models of the system, which optimize the balance between detail and efficiency; and 2) the study of dynamics-mediated properties of protein assemblies. The working philosophy of - VARIAMOLS has two complementary and strictly interconnected aspects: on the one hand, the theoretical and algorithmic advancement of the methods currently employed to represent and simulate biomolecules; on the other hand, the systematic application - of the developed methods to real-life case studies of great relevance for medical science and technology, with a particular focus on viruses and antibodies. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Italy - - - VARIAMOLS - - - ERC-2017-STG - - - 758588 - - - - - UNIVERSITEIT LEIDEN - UNIVERSITEIT LEIDEN - - - EUR 1 499 956 - - - From colloidal joints to reconfigurable matter - - - EUR 1 499 956 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Self-assembly of colloidal particles has emerged as the most promising strategy to obtain fundamental insights into otherwise prohibitively complex systems as well as to create new functional materials from the bottom up. - However, most self-assembled colloidal structures are static and thus limited in their functionality. - - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - RECONFMATTER - - - ERC-2017-STG - - - 758383 - - - - - THE UNIVERSITY OF SUSSEX - THE UNIVERSITY OF SUSSEX - - - EUR 1 488 763 - - - Genomic basis of convergent evolution in the Trinidadian Guppy - - - EUR 1 488 763 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Many species have independently evolved similar phenotypes in response to similar environmental challenges. This phenomenon, termed convergent evolution, reflects both the power and the limits of adaptation. However, we often - do not know at what scale evolution has repeated itself: did selection act on the same genes in different populations or species, or did convergence result from selection on different genes? This is because, until recently, it has not been possible - to investigate the genomic basis of evolution in most systems, limiting our understanding of the factors that facilitate or inhibit convergence and adaptation. To fully understand convergent evolution we need to query the genomic response to - selection and determine genotype-phenotype links in systems where convergent adaptation is well established. The Trinidadian guppy (Poecilia reticulata) is a system that offers the opportunity to test the roles of multiple factors in convergent - evolution: this species includes multiple natural and experimentally established populations that have repeatedly evolved similar phenotypes under similar predation environments. I propose to fully characterize the genomic-basis of repeated adaptive - evolution in guppies. Aim 1 will identify regions that repeatedly show signatures of selection, and will contrast the nature of selection in natural and experimental populations that differ in age and levels of founding genetic diversity. Aim 2 will - identify genomic regions associated with phenotypes that are known to play a significant role in local adaptation in the guppy using quantitative genetics approaches. I will then directly test the effects of candidate genes using novel functional - genomic approaches, as detailed in Aim 3. Overall, this project will test whether repeated selection led to convergence at the genomic level, determine the genetic basis of convergent adaptations, and ultimately understand how convergent evolution - has occurred in an important wild system. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - GUPPYCon - - - ERC-2017-STG - - - 758382 - - - - - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - - - EUR 1 293 023 - - - Universality and chaos in PT-symmetric quantum systems - - - EUR 1 293 023 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The world of our daily experiences, described by classical physics, is built out of fundamental particles, governed by the laws of quantum mechanics. The striking difference between quantum and classical behaviour becomes most - apparent in the realm of chaos, an extreme sensitivity to initial conditions, which is common in classical systems but impossible under quantum laws. The investigation of characteristic features of quantum systems whose classical counterparts are - chaotic has illuminated foundational problems and led to a variety of technological applications. Traditional quantum theory focuses on the description of closed systems without losses. Every realistic system, however, contains unwanted losses and - dissipation, but the idea to engineer them to generate desirable effects has recently come into the focus of scientific attention. The surprising properties of quantum systems with balanced gain and loss (PT-symmetric systems) have sparked much - interest. The first experiments on PT-symmetry in optics have been identified as one of the top ten physics discoveries of the past decade in Nature Physics. New experimental areas are rapidly emerging. Our understanding of PT-symmetric quantum - systems, however, is still limited. One major shortcoming is that the emergence of chaos and universality in these systems is hitherto nearly unexplored. I propose to investigate PT-symmetric quantum chaos to establish this new research area and - overturn some common perceptions in the existing fields of PT-symmetry and quantum chaos. Ultimately this will lead to new experimental applications and quantum technologies. Building on recent conceptual breakthroughs I have made, I will a) identify - spectral and dynamical features of chaos in PT-symmetric quantum systems, b) establish new universality classes, c) provide powerful semiclassical tools for the simulation of generic quantum systems, and d) facilitate experimental applications in - microwave cavities and cold atoms. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - CHAOS-PIQUANT - - - ERC-2017-STG - - - 758453 - - - - - UNIVERSITEIT LEIDEN - UNIVERSITEIT LEIDEN - - - EUR 1 847 500 - - - Visualizing melting magnetic order and spin fluctuations in the cuprates - - - EUR 1 847 500 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The aim of this proposal is to bring new insight and understanding into the remarkable phase diagram of the cuprates, representing the larger family of unconventional superconductors, by visualizing the process of melting - magnetic order and the resulting spin fluctuations (magnons) on the atomic scale. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - SpinMelt - - - ERC-2017-STG - - - 758572 - - - - - UNIVERSITY OF DURHAM - UNIVERSITY OF DURHAM - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 1 444 980 - - - THE AFTERMATH OF THE EAST ASIAN WAR OF 1592-1598. - - - EUR 1 444 980 - - - United Kingdom - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Aftermath seeks to understand the legacy of the East Asian War of 1592-1598. This conflict involved over 500,000 combatants from Japan, China, and Korea; up to 100,000 Korean civilians were abducted to Japan. The war caused - momentous demographic upheaval and widespread destruction, but also had long-lasting cultural impact as a result of the removal to Japan of Korean technology and skilled labourers. The conflict and its aftermath bear striking parallels to events in - East Asia during World War 2, and memories of the 16th century war remain deeply resonant in the region. However, the war and its immediate aftermath are also significant because they occurred at the juncture of periods often characterized as - “medieval” and “early modern” in the East Asian case. What were the implications for the social, economic, and cultural contours of early modern East Asia? What can this conflict tell us about war “aftermath” across historical periods and about such - periodization itself? There is little Western scholarship on the war and few studies in any language cross linguistic, disciplinary, and national boundaries to achieve a regional perspective that reflects the interconnected history of East Asia. - Aftermath will radically alter our understanding of the region’s history by providing the first analysis of the state of East Asia as a result of the war. The focus will be on the period up to the middle of the 17th century, but not precluding - ongoing effects. The team, with expertise covering Japan, Korea, and China, will investigate three themes: the movement of people and demographic change, the impact on the natural environment, and technological diffusion. The project will be the - first large scale investigation to use Japanese, Korean, and Chinese sources to understand the war’s aftermath. It will broaden understandings of the early modern world, and push the boundaries of war legacy studies by exploring the meanings of - “aftermath” in the early modern East Asian context. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - Aftermath - - - ERC-2017-STG - - - 758347 - - - - - FUNDACIO INSTITUT DE CIENCIES FOTONIQUES - FUNDACIO INSTITUT DE CIENCIES FOTONIQUES - - - EUR 1 789 165 - - - Probing nanoscale and femtosecond fluctuations in high temperature superconductors - - - EUR 1 789 165 - - - Spain - Spain - - - Research Organisations - Research Organisations - - One of the major outstanding challenges in condensed matter physics is the origin of high temperature superconductivity. Low temperature BCS superconductivity is mediated by the electron-phonon interaction, but this - interaction is believed to be too weak to explain high temperature superconductivity. Instead electron interactions are considered responsible, but experimental proof has been difficult to obtain. Despite over thirty years of research, the mechanism - responsible for generating the superconducting state still remains unknown. - - - 2022-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Spain - - - SeeSuper - - - ERC-2017-STG - - - 758461 - - - - - UNIVERSITY COLLEGE LONDON - UNIVERSITY COLLEGE LONDON - - - EUR 1 499 998 - - - Design of Mixed Anion Inorganic Semiconductors for Energy Conversion - - - EUR 1 499 998 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Multi-component systems offer the chemical and structural flexibility necessary to meet the needs of next-generation energy conversion. The vast majority of work in the field has focused on mixed-metal compounds. DISCOVER will - computationally explore mixed-anion compounds. These are complex systems that provide significant technical challenges for atomistic and electronic structure modelling. Currently, structure-property relationships are poorly developed and there is a - distinct lack of understanding of order-disorder transitions. Crucially, no systematic approach has been established for designing new combinations which can be tailored to match the criteria for technological applications. - - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - DISCOVER - - - ERC-2017-STG - - - 758345 - - - - - UNIVERSITE CATHOLIQUE DE LOUVAIN - UNIVERSITE CATHOLIQUE DE LOUVAIN - - - EUR 1 998 125 - - - Deciphering virus-host interactions using correlated confocal-atomic force microscopy - - - EUR 1 998 125 - - - Belgium - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Viruses are a major class of pathogens that infect a variety of organisms. Infection is a multistep process that involves the concerted action of both virus and host cell machineries. The first steps of virus infection include - cell binding, cell entry and release of the viral genetic material. Entry pathways are largely defined by the preliminary interactions between viruses and their receptors at the cell surface. Those interactions determine the mechanisms of virus - attachment, uptake, and, ultimately, penetration into the cytosol. Elucidating the complex interplay between viruses and their receptors at the cell surface is an essential step towards establishing a full picture of the infection process. - - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Belgium - - - NanoVirus - - - ERC-2017-STG - - - 758224 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - THE UNIVERSITY OF MANCHESTER - - - EUR 1 498 013 - - - Past and Present Musical Encounters across the Strait of Gibraltar - - - EUR 1 498 013 - - - United Kingdom - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - MESG explores how the notion of a collective European-North African cultural memory has been articulated through music for different sociopolitical ends in colonial and postcolonial contexts. Based on the notion of convivencia - (the alleged coexistence between Christians, Jews and Muslims in Islamic Spain), music has been employed as a means of social control and representation during French-Spanish colonialism in North Africa (1912–56) and as a model for multiculturalism - among North African communities in Europe today. Current scholarship on musical exchange between Europe and North Africa is fragmented, often focusing on isolated geographical case studies. There is limited understanding of how a collective cultural - memory has shaped musical practice and discourse in the colonial past and the postcolonial present. In contrast, MESG offers a comparative study of music and colonialism in the Maghreb. By examining colonial music scholarship, policy and education, - and musical encounters between different cultural groups, MESG probes the social dynamics of musical interaction at this time, framed by issues of race, imperialism and cultural memory. Second, MESG explores how the idea of a collective cultural - memory is invoked through musical collaboration today, by focusing on various genres such as Arab-Andalusian music and flamenco. Rather than separating these historical periods, however, MESG analyses how modern-day practices of musical exchange in - the region are shaped by discourses and networks formed during colonialism. Musical exchange will be read against the wider context of multiculturalism, immigration and cultural diplomacy that underpins postcolonial relations between Europe and North - Africa. Combining archival and ethnographic research, this groundbreaking project brings together for the first time different geographical, linguistic and musical specialisms, leading towards a fuller understanding of musical exchange in the region. - - 2023-03-31, Grant Agreement signed - - - 2018-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - MESG - - - ERC-2017-STG - - - 758221 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 499 375 - - - Discourse reporting in African storytelling - - - EUR 1 499 375 - - - France - France - - - Research Organisations - Research Organisations - - The project explores the role of discourse reporting in West African storytelling and the grammatical strategies used by storytellers to achieve their goals. It focuses on three phenomena characteristic of the narrative - grammar of a number of West African languages: - - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - SPEECHREPORTING - - - ERC-2017-STG - - - 758232 - - - - - FUNDACIO CENTRE DE REGULACIO GENOMICA - FUNDACIO CENTRE DE REGULACIO GENOMICA - - - EUR 1 381 286 - - - Understanding the Balbiani body: A super-organelle linked to dormancy in oocytes - - - EUR 1 381 286 - - - Spain - Spain - - - Research Organisations - Research Organisations - - Female germ cells, oocytes, are highly specialised cells. They ensure the continuity of species by providing the female genome and mitochondria along with most of the nutrients and housekeeping machinery the early embryo needs - after fertilisation. Oocytes are remarkable in their ability to survive for long periods of time, up to 50 years in humans, and retain the ability to give rise to a young organism while other cells age and die. Surprisingly little is known about - oocyte dormancy. A key feature of dormant oocytes of virtually all vertebrates is the presence of a Balbiani body, which is a non-membrane bound compartment that contains most of the organelles in dormant oocytes and disappears as the oocyte matures. - - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Spain - - - DORMANTOOCYTE - - - ERC-2017-STG - - - 759107 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 500 000 - - - Lipid asymmetry: a cellular battery? - - - EUR 1 500 000 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - It is a basic textbook notion that the plasma membranes of virtually all organisms display an asymmetric lipid distribution between inner and outer leaflets far removed from thermodynamic equilibrium. As a fundamental - biological principle, lipid asymmetry has been linked to numerous cellular processes. However, a clear mechanistic justification for the continued existence of lipid asymmetry throughout evolution has yet to be established. We propose here that lipid - asymmetry serves as a store of potential energy that is used to fuel energy-intense membrane remodelling and signalling events for instance during membrane fusion and fission. This implies that rapid, local changes of trans-membrane lipid - distribution rather than a continuously maintained out-of-equilibrium situation are crucial for cellular function. Consequently, new methods for quantifying the kinetics of lipid trans-bilayer movement are required, as traditional approaches are - mostly suited for analysing quasi-steady-state conditions. Addressing this need, we will develop and employ novel photochemical lipid probes and lipid biosensors to quantify localized trans-bilayer lipid movement. We will use these tools for - identifying yet unknown protein components of the lipid asymmetry regulating machinery and analyse their function with regard to membrane dynamics and signalling in cell motility. Focussing on cell motility enables targeted chemical and genetic - perturbations while monitoring lipid dynamics on timescales and in membrane structures that are well suited for light microscopy. Ultimately, we aim to reconstitute lipid asymmetry as a driving force for membrane remodelling in vitro. We expect that - our work will break new ground in explaining one of the least understood features of the plasma membrane and pave the way for a new, dynamic membrane model. Since the plasma membrane serves as the major signalling hub, this will have impact in almost - every area of the life sciences. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - ASYMMEM - - - ERC-2017-STG - - - 758334 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 618 125 - - - Unveiling Planet Formation by Observations and Simulations - - - EUR 1 618 125 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - With each newly detected exoplanet system, the planet formation theory is constantly gaining weight in the astrophysical research. The planets origin is a mystery which can only be solved by understanding the protoplanetary - disks evolution. Recent disk observations by the new class of interferometer telescopes are challenging the existing theory of planet formation. They reveal astonishing detailed structures of spirals and rings in the dust emission which have never - been seen before. Those structures are often claimed to be caused by embedded planets, which is difficult to explain with current models. This growing discrepancy between observation and theory forces us to realize: a novel disk modeling is essential - to move on. Separate gas or dust evolution models have reached their limit and the gap between those has to be closed. - - 2023-05-31, Grant Agreement signed - - - 2018-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - UFOS - - - ERC-2017-STG - - - 757957 - - - - - FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION - FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION - - - EUR 1 500 000 - - - Molecular and structural mechanisms for metazoan replication origin specification - - - EUR 1 500 000 - - - Switzerland - Switzerland - - - Research Organisations - Research Organisations - - Cellular life depends on the timely and accurate duplication of chromosomal DNA through semi-conservative replication to sustain genomic integrity and organismal viability. In all domains of life, DNA replication relies on - dedicated initiator proteins that recognize and bind specific genomic sites, termed replication origins, to facilitate the loading of ring-shaped replicative helicases onto DNA. While origin recognition by initiators is determined by specific DNA - sequences in prokaryotes and in the eukaryote S. cerevisiae, origin specification in higher eukaryotes instead appears to rely on chromatin context and DNA structure. Yet, how initiators help specify replication origins at the molecular level and how - their binding sites are established in higher eukaryotes remain foremost and long-standing questions in the field. This research proposal focuses on uncovering the molecular and structural principles for chromosomal binding site selection by the - eukaryotic initiator, the origin recognition complex (ORC), in metazoan systems. Employing integrated biochemical, structural, and cell-based approaches, we aim to 1) elucidate how ORC binds DNA and how DNA structural elements contribute to this - interaction, 2) determine how nucleosomes are recognized by ORC, and 3) identify auxiliary binding partners of ORC and establish how they contribute to origin specification. The outcomes of our proposed efforts will have far-reaching implications for - multiple scientific fields by defining mechanistic links between chromatin architecture and DNA replication initiation, and they will set the foundation to understand at the molecular level how the replication initiation program is altered during - cell differentiation and development. Our studies also have significant biomedical relevance, as failure to precisely replicate chromosomal DNA leads to genetic instability, which in turn underpins many human diseases, including cancer and certain - developmental disorders. - - 2023-06-30, Grant Agreement signed - - - 2018-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Switzerland - - - ORISPECIFICATION - - - ERC-2017-STG - - - 757909 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 499 756 - - - Rag-independent regulation of mTOR by Amino Acids - - - EUR 1 499 756 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - The mTOR complex 1 (mTORC1) is a master regulator of cell growth and metabolism in response to environmental cues, such as nutrients. Its dysregulation is a common feature of several life-threatening disorders, including - cancer and metabolic disease. Therefore, understanding how mTORC1 is regulated is of great importance for both basic and translational research. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - noRAG-TOR - - - ERC-2017-STG - - - 757729 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 293 763 - - - Analysis of Geometrical Effects on Dispersive Equations - - - EUR 1 293 763 - - - France - France - - - Research Organisations - Research Organisations - - We are concerned with localization properties of solutions to hyperbolic PDEs, especially problems with a geometric component: how do boundaries and heterogeneous media influence spreading and concentration of solutions. While - our first focus is on wave and Schrödinger equations on manifolds with boundary, strong connections exist with phase space localization for (clusters of) eigenfunctions, which are of independent interest. Motivations come from nonlinear dispersive - models (in physically relevant settings), properties of eigenfunctions in quantum chaos (related to both physics of optic fiber design as well as number theoretic questions), or harmonic analysis on manifolds. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - ANADEL - - - ERC-2017-STG - - - 757996 - - - - - UPPSALA UNIVERSITET - UPPSALA UNIVERSITET - - - EUR 1 121 660 - - - New mechanisms and materials for odd-frequency superconductivity - - - EUR 1 121 660 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Odd-frequency superconductivity is a very unique superconducting state that is odd in time or, equivalently, frequency, which is opposite to the ordinary behavior of superconductivity. It has been realized to be the absolute - key to understand the surprising physics of superconductor-ferromagnet (SF) structures and has also enabled the whole emerging field of superconducting spintronics. This project will discover and explore entirely new mechanisms and materials for - odd-frequency superconductivity, to both generate a much deeper understanding of superconductivity and open for entirely new functionalities. Importantly, it will generalize and apply my initial discoveries of two new odd-frequency mechanisms, - present in bulk multiband superconductors and in hybrid structures between topological insulators and conventional superconductors, respectively. In both cases odd-frequency superconductivity is generated without any need for ferromagnets or - interfaces, completely different from the situation in SF structures. The result will be a significant expansion of the concept and importance of odd-frequency superconductivity to a very wide class of materials, ranging from multiband, bilayer, and - nanoscale superconductors to topological superconductors. The project will also establish the connection between topology and odd-frequency pairing, which needs to be addressed in order to understand topological superconductors, as well as - incorporate new materials and functionality into traditional SF structures. To achieve these goals the project will develop a novel methodological framework for large-scale and fully quantum mechanical studies with atomic level resolution, solving - self-consistently for the superconducting state and incorporating quantum transport calculations. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Sweden - - - ODDSUPER - - - ERC-2017-STG - - - 757553 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 499 750 - - - Spatio-temporal Organization and Expression of the Genome - - - EUR 1 499 750 - - - France - France - - - Research Organisations - Research Organisations - - This project investigates the two-way relationship between spatio-temporal genome organization and coordinated gene regulation, through an approach at the interface between physics, computer science and biology. - - 2023-03-31, Grant Agreement signed - - - 2018-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - 4D-GenEx - - - ERC-2017-STG - - - 757956 - - - - - WEIZMANN INSTITUTE OF SCIENCE - WEIZMANN INSTITUTE OF SCIENCE - - - EUR 1 500 000 - - - Malaria Parasite Networking: Discovering Modes of Cell-Cell Communication - - - EUR 1 500 000 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Malaria, caused by Plasmodium falciparum, is a devastating parasitic disease effecting hundreds of millions of people worldwide. The parasite’s transmission cycle between humans and mosquitoes involves a remarkable series of - morphological transformations. While it is clear that, for such a complex journey, the parasites must develop means to sense their host and coordinate their actions; these modes of communication remain one of the greatest mysteries in malaria - biology. In fact, since an individual parasite is enclosed by three membranes inside its human host, the red blood cell (RBC), they were not thought to possess any communication ability. However, we discovered that these parasites, despite the - multiple barriers, are able to communicate and exchange episomal genes by releasing exosome-like vesicles, thereby opening the exciting new field of malaria parasite communication. Our initial data demonstrate that these vesicles serve as a secure - tool for the delivery of remarkable components. - - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Israel - - - MalPar.NET - - - ERC-2017-STG - - - 757743 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 499 640 - - - Organic Functionalisation of N2 Using Metal-Main Group and Metal-Metal Cooperativity - - - EUR 1 499 640 - - - France - France - - - Research Organisations - Research Organisations - - Activation and transformation of dinitrogen (N2) into other nitrogen-containing compounds is a challenge for chemists due to the inertness of this molecule. The well-established Haber-Bosch process allows transformation of - dinitrogen into ammonia (NH3) at the industrial scale through heterogeneous catalysis, but it is an energy-demanding process (1-2% of the World's annual energy consumption). The ammonia thus produced is almost totally converted into more value-added - chemicals. Similarly, in Nature, the nitrogenase enzymes are able to convert N2 into NH3 catalytically, spending a high amount of energy to produce a molecule which is subsequently transformed into amino-acids or nucleotides. At a time where energy - savings have become a major issue, alternatives to the Haber-Bosch process are desirable. Improving ammonia synthesis still prevails in current dinitrogen chemistry, despite the relative lack of utility of this molecule. Conversely, a catalytic - process affording a nitrogen-containing product directly from N2 does not exist yet, and remains a highly attractive, though challenging, goal. Given this context, the PI proposes to investigate novel molecular chemical tools capable of direct - conversion of N2 into nitrogen-containing organic compounds under mild conditions, while approaching the catalysis problem from a new direction. Two unprecedented strategies relying on the symbiotic reactivity of two partners towards dinitrogen will - be detailed herein. In the first one, metal-boron frustrated Lewis pairs (FLPs) will help activate and functionalise N2, thus unlocking the thus far missing FLP chemistry of this small molecule. In the second one, it is proposed to explore the virgin - territory of N2's cycloaddition reactivity, thanks to bimetallic cooperativity. By the careful examination of stoichiometric reactions considered as key steps of putative catalytic cycles, tackling the "Holy Grail" of catalysis will be facilitated. - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - OrFuNCo - - - ERC-2017-STG - - - 757501 - - - - - WEIZMANN INSTITUTE OF SCIENCE - WEIZMANN INSTITUTE OF SCIENCE - - - EUR 1 494 000 - - - Deciphering the computations underlying visual processing:Repurposing of retinal cells and how they are decoded by the visual thalamus - - - EUR 1 494 000 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Visual processing begins in the retina, with ~30 types of retinal ganglion cells (RGCs), each encodes a specific visual modality, such as edges or motion. A major challenge for deciphering the visual code is mapping the - connections between each RGC and its target neurons, such as in the lateral geniculate nucleus (LGN) and, via the LGN, the visual cortex. Recently, this challenge became even greater, as we and others revealed that the modality encoded by - RGCs—traditionally considered a fixed hardwired property of each RGC type—can be altered. Direction selective RGCs reorient their directional tuning following visual adaptation, and other RGCs change their polarity preference (On/Off) as light level - changes. These newly discovered dramatic changes in the core computations of RGCs depart from the known retinal adaptation which results in gain adjustments but no modality changes. We term them repurposing. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Israel - - - RetinalRepurposing - - - ERC-2017-STG - - - 757732 - - - - - THE UNIVERSITY OF EDINBURGH - THE UNIVERSITY OF EDINBURGH - UNIVERSITY COLLEGE LONDON - - - EUR 1 425 440 - - - Syntax shaped by cognition: transforming theories of syntactic systems through laboratory experiments - - - EUR 1 425 440 - - - United Kingdom - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Human language is incredibly diverse: languages differ at all levels of linguistic structure from phonetics to syntax. But behind these differences there are intriguing similarities, patterns that reappear across many - languages, and others that rarely crop up. A foundational goal of linguistics is to distil a set of principles explaining the shared features of our languages by appealing to properties of the human cognitive and linguistic system. While many such - principles have been formulated, throughout the history of the field, little direct behavioural evidence has been offered for them. Indeed, the connection between common features of language systems and cognition is controversial in the broader - community of scientists studying language from different perspectives. Longstanding debates center around whether such constraints exist, what features of cognition they might reflect, and if they are specific to language. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - SYNCOG - - - ERC-2017-STG - - - 757643 - - - - - HELSINGIN YLIOPISTO - HELSINGIN YLIOPISTO - - - EUR 1 908 652 - - - From processes to modelling of methane emissions from trees - - - EUR 1 908 652 - - - Finland - Finland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Atmospheric concentration of the strong greenhouse gas methane (CH4) is rising with an increased annual growth rate. Biosphere has an important role in the global CH4 budget, but high uncertainties remain in the strength of - its different sink and source components. Among the natural sources, the contribution of vegetation to the global CH4 budget is the least well understood. Role of trees to the CH4 budget of forest ecosystems has long been overlooked due to the - perception that trees do not play a role in the CH4 dynamics. Methanogenic Archaea were long considered as the sole CH4 producing organisms, while new findings of aerobic CH4 production in terrestrial vegetation and in fungi show our incomplete - understanding of the CH4 cycling processes. Enclosure measurements from trees reveal that trees can emit CH4 and may substantially contribute to the net CH4 exchange of forests. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Finland - - - MEMETRE - - - ERC-2017-STG - - - 757695 - - - - - THE UNIVERSITY OF EDINBURGH - THE UNIVERSITY OF EDINBURGH - - - EUR 1 497 755 - - - Modelling the genomic landscapes of selection and speciation - - - EUR 1 497 755 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Understanding how natural selection, random genetic drift and demographic events interact to generate and maintain genetic and species diversity has been the central focus of population genetics for many decades. We now have - the necessary genome sequence data to make detailed and powerful inferences about the evolutionary past of populations and species, yet our ability to meaningfully interpret such data has remained fundamentally limited. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - ModelGenomLand - - - ERC-2017-STG - - - 757648 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 497 031 - - - ABIOtic Synthesis of RNA: an investigation on how life started before biology existed - - - EUR 1 497 031 - - - France - France - - - Research Organisations - Research Organisations - - The emergence of life is one of the most fascinating and yet largely unsolved questions in the natural sciences, and thus a significant challenge for scientists from many disciplines. There is growing evidence that ribonucleic - acid (RNA) polymers, which are capable of genetic information storage and self-catalysis, were involved in the early forms of life. But despite recent progress, RNA synthesis without biological machineries is very challenging. The current project - aims at understanding how to synthesize RNA in abiotic conditions. I will solve problems associated with three critical aspects of RNA formation that I will rationalize at a molecular level: (i) accumulation of precursors, (ii) formation of a - chemical bond between RNA monomers, and (iii) tolerance for alternative backbone sugars or linkages. Because I will study problems ranging from the formation of chemical bonds up to the stability of large biopolymers, I propose an original - computational multi-scale approach combining techniques that range from quantum calculations to large-scale all-atom simulations, employed together with efficient enhanced-sampling algorithms, forcefield improvement, cutting-edge analysis methods and - model development. - - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - ABIOS - - - ERC-2017-STG - - - 757111 - - - - - FORSCHUNGSZENTRUM JULICH GMBH - FORSCHUNGSZENTRUM JULICH GMBH - - - EUR 1 465 944 - - - Controlled Mechanical Manipulation of Molecules - - - EUR 1 465 944 - - - Germany - Germany - - - Research Organisations - Research Organisations - - The idea to freely control the atomic-scale structure of matter has intrigued scientists for many decades. The low-temperature scanning probe microscope (LT SPM) has become the instrument of choice for this task since it - allows the rearrangement of atoms and molecules on a surface. There is, however, no generic SPM-based method for the manipulation of molecules beyond lateral rearrangement. The goal of this project is to develop controlled mechanical manipulation of - molecules (CM3) in which a LT SPM is used to handle large organic molecules in three dimensions with optimal control over position, orientation and shape. CM3 will become a game-changing technique for research on molecular properties and - molecular-scale engineering, because it combines fully deterministic manipulation with broad access to molecular degrees of freedom for the first time. In CM3 the tip is attached to a single reactive atom within a molecule. Tip displacement guides - the molecule into a desired conformation while the surface provides a second (weaker) fixation. The fundamental challenge addressed by this project is the identification of precise molecular conformations at any time during manipulation. The solution - is a big data approach where large batches of automatically recorded SPM manipulation data are structured using machine learning and interpreted by comparison to atomistic simulations. The key idea is a comparison of entire conformation spaces at - once, which is robust, even if the theory is not fully quantitative. The obtained map of the conformation space is used to determine molecular conformations during manipulation by methods of control theory. The effectiveness of this approach will be - demonstrated in experiments that unambiguously reveal the structure-conductance relation for a series of molecules and that realize the engineering paradigm of piecewise assembly on the molecular scale by constructing a direct current rotor / motor - from individual components. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - CM3 - - - ERC-2017-STG - - - 757634 - - - - - FREIE UNIVERSITAET BERLIN - FREIE UNIVERSITAET BERLIN - - - EUR 1 486 800 - - - Complexity Inside NP - A Computational Geometry Perspective - - - EUR 1 486 800 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Traditional complexity theory focuses on the dichotomy between P and NP-hard problems. Lately, it has become increasingly clear that this misses a major part of the picture. Results by the PI and others offer glimpses on a - fascinating structure hiding inside NP: new computational problems that seem to lie between polynomial and NP-hard have been identified; new conditional lower bounds for problems with large polynomial running times have been found; long-held beliefs - on the difficulty of problems in P have been overturned. Computational geometry plays a major role in these developments, providing some of the main questions and concepts. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - CGinsideNP - - - ERC-2017-STG - - - 757609 - - - - - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - - - EUR 1 499 292 - - - Next Generation Machine Intelligence for Medical Image Representation and Analysis - - - EUR 1 499 292 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Machines capable of analysing and interpreting medical scans with super-human performance would transform healthcare as much as medical imaging itself did over the last century. With an increasing complexity and volume of data - the interpretation of images and extraction of clinically useful information push human abilities to the limit. There is high risk that critical patterns of disease go undetected. We require powerful and trustworthy computational tools based on - machine intelligence to support experts and go beyond human performance to tackle the major challenges in clinical practice. Two key ingredients are currently missing: 1) interpretable statistical representations that capture important information - while reducing complexity; 2) intelligent algorithms that leverage knowledge across multiple tasks to solve the most challenging problems such as early detection of pathology. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - MIRA - - - ERC-2017-STG - - - 757173 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 937 000 - - - Artificial cell-cell interactions for light switchable cell organization and signaling - - - EUR 1 937 000 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - The bottom-up assembly of tissue from cellular building blocks constitutes a promising, yet highly challenging approach to engineer complex tissues. The challenge lies in controlling cell-cell interactions, which determine how - cells organize with respect to each other, how they work together and consequently whether such a multicellular architecture will be functional. The limited spatial and temporal control over cell-cell interactions current biological and chemical - approaches provide severely restricts bottom-up tissue engineering. Here, I propose a new way to control cell-cell interactions. I aim to regulate cell-cell interactions with visible light using proteins that reversibly homo- or heterodimerize under - blue or red light. These photoswitchable cell-cell interactions provide sustainable, non-invasive, dynamic and reversible control over cell-cell interactions with unprecedented spatial and temporal resolution. First of all, we will focus on various - light dependent protein interactions to mediate cell-cell contacts. The detailed characterization (strength, dynamics, interaction modes and orthogonality) of these new photoswitchable cell-cell interactions will provide the framework for the - bottom-up construction of tissue-like structures. Secondly, we will use these photoswitchable cell-cell interactions to assemble cells into multicellular architectures with predictable and programmable organization. The dynamic and reversible nature - of the photoswitchable contacts will allow us to locally alter interactions at any point in time, to rearrange and obtain asymmetric multicellular structures, which are typical of tissues. Finally, we will also explore how the photoswitchable - cell-cell interactions alter cell behavior and signaling. Ultimately, this will pave the way for the bottom-up assembly of multicellular architectures, enabling us to control precisely and dynamically their organization in space and time as well as - regulate how cells work together. - - 2023-06-30, Grant Agreement signed - - - 2018-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - ARTIST - - - ERC-2017-STG - - - 757593 - - - - - UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA - UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA - - - EUR 1 337 480,94 - - - Unveiling the dark universe with gravitational waves: Black holes and compact stars as laboratories for fundamental physics - - - EUR 1 337 480,94 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In recent years, our theoretical understanding of the strong-field regime of gravity has grown in parallel with the observational confirmations that culminated in the landmark detection of gravitational waves (GWs). This - synergy of breakthroughs at the observational, technical, and conceptual level offers the unprecedented opportunity to merge traditionally disjoint areas, and to make strong gravity a precision tool to probe fundamental physics. - - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Italy - - - DarkGRA - - - ERC-2017-STG - - - 757480 - - - - - ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM - ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM - - - EUR 1 498 544 - - - Dissecting the cellular and molecular dynamics of bone marrow fibrosis for improved diagnostics and treatment - - - EUR 1 498 544 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Bone marrow (BM) fibrosis is the continuous replacement of blood forming cells in the bone marrow by scar tissue, ultimately leading to failure of the body to produce blood cells. Primary myelofibrosis (PMF), an incurable - blood cancer, is the prototypic example of the step-wise development of BM fibrosis. The specific mechanisms that cause BM fibrosis are not understood, in particular as the cells driving fibrosis have remained obscure. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - deFIBER - - - ERC-2017-STG - - - 757339 - - - - - UNIVERSITA DEGLI STUDI DI TORINO - UNIVERSITA DEGLI STUDI DI TORINO - - - EUR 1 051 590 - - - New Models of Sanctity in Italy (1960s-2010s).A Semiotic Analysis of Norms, Causes of Saints, Hagiography, and Narratives - - - EUR 1 051 590 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In cultures with a strong Catholic tradition saints represent models of life perfection, dialectically elaborated by a plurality of subjects and expressed in a thick intertextual network. Since the Second Vatican Council - (1962-1965), when the Church promoted a policy of adaptation of her tradition to the modern world, the modeling of sanctity has undergone a deep transformation. In a context of global change, new models of sanctity have assumed a central role in - guiding the faithful by proposing a renewed religious alternative to growing secularization. - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Italy - - - NeMoSanctI - - - ERC-2017-STG - - - 757314 - - - - - KOBENHAVNS UNIVERSITET - KOBENHAVNS UNIVERSITET - - - EUR 1 499 952 - - - Pervasive Upstream Non-Coding Transcription Underpinning Adaptation - - - EUR 1 499 952 - - - Denmark - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Genomic DNA represents the blueprint of life: it instructs solutions to challenges during life cycles of organisms. Curiously DNA in higher organisms is mostly non-protein coding (e.g. 97% in human). The popular “junk-DNA” - hypothesis postulates that this non-coding DNA is non-functional. However, high-throughput transcriptomics indicates that this may be an over-simplification as most non-coding DNA is transcribed. This pervasive transcription yields two molecular - events that may be functional: 1.) resulting long non-coding RNA (lncRNA) molecules, and 2.) the act of pervasive transcription itself. Whereas lncRNA sequences and functions differ on a case-by-case basis, RNA polymerase II (Pol II) transcribes most - lncRNA. Pol II activity leaves molecular marks that specify transcription stages. The profiles of stage-specific activities instruct separation and fidelity of transcription units (genomic punctuation). Pervasive transcription affects genomic - punctuation: upstream lncRNA transcription over gene promoters can repress downstream gene expression, also referred to as tandem Transcriptional Interference (tTI). Even though tTI was first reported decades ago a systematic characterization of tTI - is lacking. Guided by my expertise in lncRNA transcription I recently identified the genetic material to dissect tTI in plants as an independent group leader. My planned research promises to reveal the genetic architecture and the molecular hallmarks - defining tTI in higher organisms. Environmental lncRNA transcription variability may trigger tTI to promote organismal responses to changing conditions. We will address the roles of tTI in plant cold response to test this hypothesis. I anticipate our - findings to inform on the fraction of pervasive transcription engaging in tTI. My proposal promises to advance our understanding of genomes by reconciling how the transcription of variable non-coding DNA sequences can elicit equivalent functions. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Denmark - - - PUNCTUATION - - - ERC-2017-STG - - - 757411 - - - - - WEIZMANN INSTITUTE OF SCIENCE - WEIZMANN INSTITUTE OF SCIENCE - - - EUR 1 499 999 - - - Decoding the host-pathogen interspecies crosstalk at a multiparametric single-cell level - - - EUR 1 499 999 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Bacterial pathogens remain a significant threat to global health, necessitating a better understanding of host-pathogen biology. While various evidence point to early infection as a key event in the eventual progression to - disease, our recent preliminary data show that during this stage, highly adaptable and dynamic host cells and bacteria engage in complex, diverse interactions that contribute to well-documented heterogeneous outcomes of infection. However, current - methodologies rely on measurements of bulk populations, thereby overlooking this diversity that can trigger different outcomes. This application focuses on understanding heterogeneity during the first stages of infection in order to reduce the - complexity of these interactions into informative readouts of population physiology and predictors of infection outcome. We will apply multiparametric single-cell analysis to obtain an accurate and complete description of infection with the enteric - intracellular pathogen Salmonella of macrophages in vitro, and in early stages of mice colonization. We will characterize the molecular details that underlie distinct infection outcomes of individual encounters, to reconstruct the repertoire of host - and pathogen strategies that prevail at critical stages of early infection. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Israel - - - DecodingInfection - - - ERC-2017-STG - - - 756653 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 491 909 - - - Planetary accretion and migration in discs over all ages - - - EUR 1 491 909 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - The goal of this ERC proposal is to make significant progress in our understanding how planetary systems form in protoplanetary discs. In this ambitious research programme I will answer these three key questions: - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - PAMDORA - - - ERC-2017-STG - - - 757448 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 1 930 437 - - - Tunable optoelectronic devices by strain engineering of 2D semiconductors - - - EUR 1 930 437 - - - Spain - Spain - - - Research Organisations - Research Organisations - - The goal of 2D-TOPSENSE is to exploit the remarkable stretchability of two-dimensional semiconductors to fabricate optoelectronic devices where strain is used as an external knob to tune their properties. - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Spain - - - 2D-TOPSENSE - - - ERC-2017-STG - - - 755655 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 1 759 732,50 - - - HYbrid PERovskites for Next GeneratION Solar Cells and Lighting - - - EUR 1 759 732,50 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - An emerging class of materials called hybrid perovskites is poised to revolutionise how power is both produced and consumed by enabling the production of highly-efficient, tunable solar photovoltaics (PV) and light-emitting - diodes (LEDs) at exceptionally low cost. Although the efficiencies of perovskite devices are rising fast, both PV and LEDs fall short of out-performing current technology and reaching their theoretical performance limits. To achieve their full - potential, parasitic non-radiative losses and bandgap instabilities from ionic segregation must be fundamentally understood and eliminated. HYPERION will address these issues by i) elucidating the origins of non-radiative decay and ion segregation in - films and devices, ii) devising means to eliminate these processes, and iii) implementing optimised materials into boundary-pushing PV and LED devices. This will be achieved through a groundbreaking hierarchical analysis of the perovskite structures - that not only characterises thin films and interfaces, but also the sub-units that comprise them, including grain-to-grain and sub-granular properties. The optoelectronic behaviour on these scales will be simultaneously correlated with local - structural and chemical properties. HYPERION will use this fundamental understanding to eliminate non-radiative losses and ionic segregation on all scales through passivation treatments and compositional control. Addressing these knowledge gaps in - the operation of perovskites will produce fundamental semiconductor science discoveries as well as illuminate routes to yield optimised and functional perovskites across the broad bandgap range 1.2–3.0 eV. These will be used to demonstrate - all-perovskite tandem PV devices with efficiency exceeding crystalline silicon (26%), and white light LEDs with efficacies surpassing fluorescent light (50 lm/W). The work will realise the promise of perovskite technology as a versatile and scalable - energy solution to secure a sustainable future. - - 2022-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - HYPERION - - - ERC-2017-STG - - - 756962 - - - - - UNIVERSITAT WIEN - UNIVERSITAT WIEN - - - EUR 1 497 202 - - - Atomic precision materials engineering - - - EUR 1 497 202 - - - Austria - Austria - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Despite more than fifty years of scientific progress since Richard Feynman's 1959 vision for nanotechnology, there is only one way to manipulate individual atoms in materials: scanning tunneling microscopy. Since the late - 1980s, its atomically sharp tip has been used to move atoms over clean metal surfaces held at cryogenic temperatures. Scanning transmission electron microscopy, on the other hand, has been able to resolve atoms only more recently by focusing the - electron beam with sub-atomic precision. This is especially useful in the two-dimensional form of hexagonally bonded carbon called graphene, which has superb electronic and mechanical properties. Several ways to further engineer those have been - proposed, including by doping the structure with substitutional heteroatoms such as boron, nitrogen, phosphorus and silicon. My recent discovery that the scattering of the energetic imaging electrons can cause a silicon impurity to move through the - graphene lattice has revealed a potential for atomically precise manipulation using the Ångström-sized electron probe. To develop this into a practical technique, improvements in the description of beam-induced displacements, advances in heteroatom - implantation, and a concerted effort towards the automation of manipulations are required. My project tackles these in a multidisciplinary effort combining innovative computational techniques with pioneering experiments in an instrument where a - low-energy ion implantation chamber is directly connected to an advanced electron microscope. To demonstrate the power of the method, I will prototype an atomic memory with an unprecedented memory density, and create heteroatom quantum corrals - optimized for their plasmonic properties. The capability for atom-scale engineering of covalent materials opens a new vista for nanotechnology, pushing back the boundaries of the possible and allowing a plethora of materials science questions to be - studied at the ultimate level of control. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Austria - - - ATMEN - - - ERC-2017-STG - - - 756277 - - - - - THE UNIVERSITY OF EDINBURGH - THE UNIVERSITY OF EDINBURGH - - - EUR 1 418 195 - - - The Rise of Placental Mammals: Dissecting an Evolutionary Radiation - - - EUR 1 418 195 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Mammals are ubiquitous, with over 5000 species across the globe. But how did mammals become so successful? There is vigorous debate among palaeontologists: did mammals explosively diversify after a sudden environmental crisis - knocked out dinosaurs at the end of the Cretaceous (~66 million years ago) or rise to dominance more slowly, alongside the dinosaurs? The debate persists because we still know very little about those mammals that flourished during the ~10 million - years after the end-Cretaceous extinction (the early Paleogene), as they are largely ignored because their ‘archaic’ anatomy has long confounded palaeontologists. This project will use a wealth of newly discovered fossils and state-of-the-art - analytical techniques to finally untangle the evolutionary story of these ~200 critical species. We will comprehensively study the anatomy of ‘archaic’ species using state-of-the-art imaging technology and build a species-level genealogy placing - these long-mysterious mammals in the context of their Cretaceous forebears and modern mammals. Cutting-edge quantitative methods for studying evolution, including novel techniques developed here, will be applied to the family tree to date the origin - of placental mammals and the major modern groups, determine what effect the end-Cretaceous extinction had on mammalian biodiversity, quantify the tempo and mode of the placental radiation, and explicitly test for potential drivers of mammalian - diversification. This will give ground-breaking insight into how major groups become successful over evolutionary time and how biodiversity is affected and reset by dramatic environmental changes, a pressing concern in today’s rapidly changing world. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - PalM - - - ERC-2017-STG - - - 756226 - - - - - UNIVERSIDAD DE MALAGA - UNIVERSIDAD DE MALAGA - - - EUR 1 203 125 - - - Advanced Analytics to Empower the Small Flexible Consumers of Electricity - - - EUR 1 203 125 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - David against Goliath: Could small consumers of electricity compete in the wholesale markets on equal footing with the other market agents? Yes, they can and FlexAnalytics will show how. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Spain - - - FlexAnalytics - - - ERC-2017-STG - - - 755705 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 2 498 485 - - - Parallel Orthographic Processing and Reading - - - EUR 2 498 485 - - - France - France - - - Research Organisations - Research Organisations - - The project centers on a new computational model, the POP-R model, that implements two original, and apparently contradictory, hypotheses with respect to the processing of orthographic information spanning several words during - silent reading for meaning: 1) orthographic information spanning several words is processed in parallel and integrated within a single pool of location-invariant orthographic representations; 2) readers process multiple word identities in parallel - and keep track of the positions of these words by associating word identities with spatiotopic locations in short-term memory. The apparent contradiction is solved in POP-R by the triangular connectivity between gaze-centered letter detectors, - spatiotopic word identities, and location-invariant orthographic representations. Evidence in favor of the first hypothesis has been obtained with a novel Flanking Letters Lexical Decision task. The second hypothesis predicted the existence of a - sentence superiority effect in a novel Rapid Parallel Visual Presentation paradigm, for which we have preliminary evidence. Other key predictions of the POP-R model will be tested in behavioral experiments using these new techniques, and EEG and MEG - recordings will be used to specify the spatio-temporal dynamics of the neural processes underlying orthographic pooling and parallel word identification. Experiments with primary school children will plot the developmental trajectory of these - processes, and sentence reading experiments measuring eye-movements and ERPs will be used to further test the model. The project incorporates both theoretical and methodological innovation within a novel perspective on reading that places - orthographic processing at the very heart of the reading network. This new perspective is expected to facilitate the integration of knowledge concerning low-level visual processing and eye-movement control with higher-level semantic and syntactic - processing during silent reading for meaning. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - France - - - POP-R - - - ERC-2016-ADG - - - 742141 - - - - - UNIVERSITAET ZU KOELN - UNIVERSITAET ZU KOELN - - - EUR 1 499 891 - - - The mechanical evolution from biting-chewing to piercing-sucking in insects - - - EUR 1 499 891 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Insects are extremely efficient feeders that impact on the world's ecosystems and our agriculture with their feeding capabilities. Insects evolved diverse mouthpart types during ~400 million years of evolution which allowed - them to conquer many food recourses. How this feeding system evolved, in particular the transition from one mouthpart type to the other, is unclear. My idea represents the first extensive assessment of insect head mechanics applying latest - semi-automatic workflows and engineering approaches to unravel the factors driving insect mouthpart evolution and performance. - - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - MECH-EVO-INSECT - - - ERC-2017-STG - - - 754290 - - - - - THE UNIVERSITY OF EDINBURGH - THE UNIVERSITY OF EDINBURGH - - - EUR 1 499 981 - - - Search for new physics through lattice simulations - - - EUR 1 499 981 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Despite its monumental success, we have reason to think that the Standard Model of particle physics is an effective description of a more fundamental theory. In order to maximise the chances of success of experiments to - pinpoint the breakdown of this theory, it is crucial to provide precise, ab-initio theoretical predictions to compare it with. One of the main challenges in producing these predictions is to reliably take account of the non-perturbative, confining - phase of the strong interaction. So far, the most efficient way to achieve that is to use numerical lattice simulations. In this proposal, I focus on theoretical quantities involved in the search for new physics and propose an ambitious lattice - simulation programme to determine them precisely. Firstly, I propose to predict rare kaon decays amplitudes. These decays are extremely rare in the Standard Model and are expected to be sensitive to new physics. Secondly, I propose to determine how - to include isospin breaking effects in the calculation of the anomalous magnetic moment of the muon and meson leptonic and semi-leptonic decay rates. Including these effects is a highly non-trivial task which is necessary to push the theoretical - precision of these observables beyond the percent level in order to provide a higher constraint on the Standard Model. Thirdly, I propose to explore holographic cosmology, an ambitious and innovative alternative to ΛCDM, the "standard model" of - cosmology. Finally, all these projects will directly contribute to the development of Grid, the emerging world-leading software solution for lattice simulations. All these projects are strongly pushing the boundaries of the application of lattice - simulations and the results will be confronted with experimental measurements within the next five years. This proposal focuses on supporting world-leading particle physics experiments and I will deliver high-impact results which have the potential - to uncover new physics beyond the Standard Model. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - NewPhysLat - - - ERC-2017-STG - - - 757646 - - - - - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - - - EUR 1 636 710 - - - Armoring multifunctional T cells for cancer therapy - - - EUR 1 636 710 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Adoptive T cell therapy (ACT) is a powerful approach to treat even advanced cancer diseases where poor prognosis calls for innovative treatments. However ACT is critically limited by insufficient T cell infiltration into the - tumor, T cell activation at the tumor site and local T cell suppression. Few advances have been made in the field to tackle these limitations besides increasing T cell activation. My group has focussed on these unaddressed issues but came to realise - that tackling these one by one will not be sufficient. I have developed a panel of unpublished chemokine receptors and innovative modular antibody-activated receptors which have the potential to overcome the limitations of ACT against solid tumors. - This ground-breaking portfolio places my group in the unique position to address combination of synergistic receptors and enable cellular therapies in previously unsuccessful indications. My project will provide the rationale for provision of an - effective cancer treatment. The goal is to develop the next generation of ACT through T cell engineering both by forced expression of migratory and activating receptors and simultaneous deletion of immune suppressive molecules by gene editing. - ARMOR-T will provide the basis for further preclinical and clinical development of a pioneering cellular product devoid of the limitations of available products to date. I will prove 1) synergy between migratory and modular activating receptors, 2) - feasibility to integrate gene editing into a T cell expansion protocol, 3) synergy between gene editing, migratory and modular receptors and 4) efficacy, safety and mode of action. The main work of the project will be carried out in models of - pancreatic cancer. The ARMOR-T platform will subsequently be translated to other cancer entities where response to ACT is likely such as melanoma, breast or colon cancer, providing less toxic and more effective therapies to otherwise untreatable - disease. - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - ARMOR-T - - - ERC-2017-STG - - - 756017 - - - - - UNIVERSITAT DE VALENCIA - UNIVERSITAT DE VALENCIA - - - EUR 1 499 587 - - - Fluorescence-based photosynthesis estimates for vegetation productivity monitoring from space - - - EUR 1 499 587 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Global food security will remain a worldwide concern for the next 50 years and beyond. Agricultural production undergoes an increasing pressure by global anthropogenic changes, including rising population, increased protein - demands and climatic extremes. Because of the immediate and dynamic nature of these changes, productivity monitoring measures are urgently needed to ensure both the stability and continued increase of the global food supply. Europe has expressed - ambitions to keep its fingers on the pulse of its agricultural lands. In response to that, this proposal - named SENTIFLEX - is dedicated to developing a European vegetation productivity monitoring facility based on the synergy of Sentinel-3 (S3) - with FLEX satellite fluorescence data. ESA's 8th Earth Explorer FLEX is the first mission specifically designed to globally measure Sun-Induced chlorophyll Fluorescence (SIF) emission from terrestrial vegetation. These two European Earth observation - missions offer immense possibilities to increase our knowledge of the basic functioning of the Earth’s vegetation, i.e., the photosynthetic activity of plants resulting in carbon fixation. Two complementary approaches are envisioned to realize - quantification of photosynthesis through satellite SIF and S3. First, the work seeks to advance the science in establishing and consolidating relationships between canopy-leaving SIF and unbiased estimates of photosynthesis of the plants, thereby - disentangling the role of dynamic vegetative and atmospheric variables. Second, consolidated relationships between SIF and photosynthesis will be used to build a FLEX-S3 data processing assimilation scheme through process-based vegetation models that - will deliver spatiotemporally highly resolved information on Europe’s vegetation productivity. To streamline all these datasets into a prototype vegetation productivity monitoring facility, new data processing concepts will be introduced such as the - emulation of radiative transfer models. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Spain - - - SENTIFLEX - - - ERC-2017-STG - - - 755617 - - - - - BRITISH SCHOOL AT ATHENS - - - EUR 164 653,20 - - - TRAvelling Ceramic Technologies as markers of human mobility in the Aegean - - - EUR 164 653,20 - - - United Kingdom - - - Research Organisations - - The main aim of TRACT is to demonstrate that the informed and interdisciplinary study of ancient pottery can shed new light on past human mobility. Based on the premise that the spread of technology involved in pottery making - requires the physical movement of people, the project will adopt an inter-disciplinary methodology designed to investigate instances of technological transfer and hence mobility of potters. The methodology comprises macroscopic study of the - vessel-forming methods in combination with petrographic and chemical analysis of pottery and raw material samples. An important addition is the study of modern instances of potters’ mobility in the Aegean. Altogether, this represents a novel - approach, which will be employed to a specific study focused on potters from the island of Aegina during the Late Bronze Age. TRACT will investigate the spread of a particular pottery tradition developed on the island of Aegina along the Euboean - Gulf, an important corridor that facilitated movement of goods and people. Furthermore, the chosen case study will aim to shed light on the underpinnings of such movement, its duration, scale, as well as interaction of potters with new landscapes and - receiving communities. Therefore, TRACT will contribute to the current debate on mobility by presenting thoroughly researched case study of craftsmen mobility, and elaborate a coherent methodology that can be universally applied. The choice of the - Fitch Laboratory of the British School at Athens as a hosting institution will not only enable a high-level training through research but also, due to the supervisor’s interest in mobility of potters’ mobility and previous research on pottery - production on the island of Aegina, it constitutes a perfect match that will provide a substantial boost to career opportunities for the experienced researcher and strengthen the position of the Laboratory as a centre of excellence for the study of - craftspeople mobility. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - TRACT - - - H2020-MSCA-IF-2016 - - - 753569 - - - - - WEIZMANN INSTITUTE OF SCIENCE - WEIZMANN INSTITUTE OF SCIENCE - - - EUR 1 499 990 - - - Stromal stress networks underlying phenotypic plasticity and tumor fitness - - - EUR 1 499 990 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The contribution of genetic and epigenetic changes to rewiring of cancer cells into their malignant state has been much studied. But tumors are more than cancer cells and the tumor microenvironment (TME) is a key player in - tumor progression. We lack an overarching view of how, despite being genomically stable, the TME is heterogeneously reprogrammed across time and space to promote evolution of aggressive disease. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Israel - - - StroMaP - - - ERC-2017-STG - - - 754320 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 185 076 - - - DETERMINING THE FUNCTIONAL CONSEQUENCES OF TRANSCRIPTIONAL ENHANCER ACTIVATION ON ALTERNATIVE SPLICING DURING EMT - - - EUR 185 076 - - - France - - - Research Organisations - - Alternative splicing (AS) is a highly regulated process that is essential for creating the protein diversity required for correct cell-type specification. Misregulation of AS programs can lead to cellular dysfunction, - developmental problems and disease, such as cancer. Understanding how alternative splicing is regulated during development and disease is therefore capital. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - France - - - ESEMT - - - H2020-MSCA-IF-2016 - - - 752595 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - KALAHARI RESEARCH TRUST - - - EUR 2 499 244 - - - Effects of group dynamics on selection, development and demography in cooperative vertebrates - - - EUR 2 499 244 - - - United Kingdom - United Kingdom - South Africa - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - In social animals, the characteristics and dynamics of groups affect the development of individuals, the selection pressures operating on them and the demography of populations. Using existing study populations of two social - mammals (Kalahari meerkats and Damaraland mole-rats) that offer unique and complementary opportunities for research, we shall (1) explore the effects of variation in group size on growth, behaviour, hormonal status and gene regulation in both species - and test suggestions that (i) increasing group size generates divergence in development among group members and the formation of incipient castes and (ii) that breeding extends female longevity rather than reducing it; (2) assess the extent and - causes of variation in group longevity and in the frequency with which groups generate new breeding units, model the relative impact of selection operating at different levels on the evolution of cooperation, and investigate whether there is any - indication that the behaviour of individuals is adapted to increasing group persistence or proliferation; (3) examine the effects of group size and group dynamics on the dynamics of populations and their responses to variation in rainfall, - temperature and epidemic disease (TB), generalise these models to explore the population dynamics of cooperative breeders and explore their consequences for the evolution of cooperative breeding. Our work involves novel approaches to the measurement - and analysis of development, communication and gene regulation in wild animals, and to modelling multi-level selection and the dynamics of hierarchically structured populations. It will provide insight into the social mechanisms affecting individual - development, multi-level selection and the population dynamics and management of group-living animals. - - 2023-06-30, Grant Agreement signed - - - 2018-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - Group-Dynamics-TCB - - - ERC-2016-ADG - - - 742808 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSITE LIBRE DE BRUXELLES - UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6 - - - EUR 2 200 000 - - - IASI - Flux and temperature - - - EUR 2 200 000 - - - France - France - Belgium - France - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - IASI - Flux and temperature - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - France - - - IASI-FT - - - ERC-2016-ADG - - - 742909 - - - - - UNIVERSITA COMMERCIALE LUIGI BOCCONI - UNIVERSITA COMMERCIALE LUIGI BOCCONI - - - EUR 1 276 250 - - - European Integration, Populism and European Cities - - - EUR 1 276 250 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Why is it so difficult to achieve further European political integration? This question motivates the first part of the project. The standard approach in economics presumes that integration of countries reflects a tradeoff - between economic benefits and the cost of cultural heterogeneity. To assess this tradeoff, we exploit survey data to quantify cultural heterogeneity within and between EU countries, comparing it to the US. We also investigate time variation, to - assess whether economic integration led to cultural convergence. Finally, exploiting regional variation, we seek to identify a cultural core and compare it to the economic core of the EU. We conjecture the following conclusion: although European - economic integration has not led to cultural convergence, the primary obstacle to integration is not cultural heterogeneity per se, but the presence of other barriers, such as national identities or national institutions, which amplify its effects. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Italy - - - EUROPOPULISM - - - ERC-2016-ADG - - - 741643 - - - - - LINKOPINGS UNIVERSITET - LINKOPINGS UNIVERSITET - UNIVERSITY OF KENT - - - EUR 2 261 522,73 - - - Patents as Scientific Information, 1895-2020 - - - EUR 2 261 522,73 - - - Sweden - Sweden - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - “History will remember Barack Obama as the great Slayer of Patent Trolls.” The headline from the 2014 March 20 issue of Wired credits POTUS with, perhaps, an unexpected feat. Referring to companies in the sole business of - enforcing patents beyond their actual value, trolls are a recent installment in the history of an intellectual property whose ubiquitousness the Latin word PASSIM (“here and there, everywhere”) neatly captures. In the eye of the storm stands the - patent bargain: disclosure of information in return for a limited monopoly. This contractual moment makes patents a source of information, the basis of new innovation. Or does it? By posing this simple question, PASSIM’s bold take on the legitimacy - of intellectual property in the governance of informational resources follow patents as legal and informational documents during three historical “patent phases,” producing a visionary and theoretically savvy interpretation of intellectual property - that stems from its humanities-based and interdisciplinary project design. PASSIM shows a way out of current analytical gridlocks that earmark the understanding of the role of intellectual property in knowledge infrastructures—most notably the - enclosure/openness dichotomy—and provides a fresh take on the complexity of informational processes. A key steppingstone in the PI’s career, her own contribution to PASSIM will be a work of synthesis, highlighting major tendencies in the history of - patents as scientific information from 1895 to the present. Four complementary empirical studies target specific themes that strengthen PASSIM’s validity and impact: questions of copyrights in patents, scientists’ patenting strategies both - historically and today, the relationship between bibliometrics and patentometrics, and the status of the patent as a legal and informational document. Outputs include workshops, articles, monographs, policy papers and documentation of the project’s - experiences with interdisciplinary self-reflexivity. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Sweden - - - PASSIM - - - ERC-2016-ADG - - - 741095 - - - - - UNIVERSITE CATHOLIQUE DE LOUVAIN - UNIVERSITE CATHOLIQUE DE LOUVAIN - UNIVERSITY OF LONDON - - - EUR 2 495 335 - - - The origin and early development of philosophy in tenth-century al-Andalus: the impact of ill-defined materials and channels of transmission. - - - EUR 2 495 335 - - - Belgium - Belgium - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The objective of PhilAnd is to conduct a large-scale exploration of how, and under which form, philosophy appeared for the first time in al-Andalus. This issue is pivotal to understanding the history of sciences and ideas, and - the role of the Arab-Muslim world in this transfer to Medieval Europe. Its relevance today also lies in the fact that it addresses questions of cultural and religious identities, since the formative stage of philosophy in al-Andalus proved decisive - in shaping the intellectual background of many later authors from the Peninsula, whether Muslims, Jews, or Christians. At the crossroads of major lines of enquiries in scholarship and in line with recent discoveries having important chronological - implications, PhilAnd focuses on the 10th century, a period usually disregarded by historians on the assumption that philosophy as such was not cultivated in the Iberian Peninsula before the 11th-12th centuries. Its originality is also to put - emphasis on ‘ill-defined’ materials and channels of transmission, a field which remains largely unexplored. This project consists of five topics designed for highly-specialised scholars, and of another three transversal types of exploration conducted - in the form of conferences convened with leading experts in the world. The final objectives are to test the hypothesis: 1) that the emergence of philosophy in al-Andalus significantly predates the currently accepted time; and 2) that the impact of - this formative stage was considerably wider than commonly acknowledged. This project also seeks to provide a better evaluation of the originality of the first Andalusī philosophers with respect to their Oriental forerunners. This cutting-edge - investigation is likely to stimulate major changes in our perception of how this primeval stage of philosophy in al-Andalus determined the subsequent developments of rational speculation among the three monotheistic communities of the Peninsula and - the intellectual formation of Europe. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Belgium - - - PhilAnd - - - ERC-2016-ADG - - - 740618 - - - - - LEIBNIZ-INSTITUT FUER PHOTONISCHE TECHNOLOGIEN E.V. - LEIBNIZ-INSTITUT FUER PHOTONISCHE TECHNOLOGIEN E.V. - UNIVERSITY OF DUNDEE - - - EUR 1 997 973 - - - Holographic super-resolution micro-endoscopy for in-vivo applications - - - EUR 1 997 973 - - - Germany - Germany - United Kingdom - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - - Complexity of living matter currently poses the most significant barrier to modern in-vivo microscopy. Fuelled by various branches of life sciences, the race is now to increase the penetration depth of super-resolution imaging - inside living organisms. Additionally, no high-resolution in-vivo imaging technique has ever been introduced into medical, particularly surgical practice. - - - 2022-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - LIFEGATE - - - ERC-2016-COG - - - 724530 - - - - - WEIZMANN INSTITUTE OF SCIENCE - WEIZMANN INSTITUTE OF SCIENCE - - - EUR 2 488 306 - - - Towards evidence-based combinations of approved and novel cancer drugs - - - EUR 2 488 306 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Background: Molecular targeted therapy (TT; e.g., monoclonal antibodies, mAbs, and protein kinase inhibitors, PKIs) intercepts oncogene and other addictions of tumours. However, unlike chemotherapy, which employs cocktails of - drugs, only rarely does TT harness poly-pharmacology. Because lung cancer is the major cause of oncology related fatalities and many driver mutations are known, this disease offers opportunities for establishing and generalizing novel TT combinations - and their interface with the immune system. - - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Israel - - - onCOMBINE - - - ERC-2016-ADG - - - 740469 - - - - - TECHNISCHE UNIVERSITAT DARMSTADT - TECHNISCHE UNIVERSITAT DARMSTADT - - - EUR 2 548 298 - - - antiProton Unstable Matter Annihilation - - - EUR 2 548 298 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - One of the most fascinating quantum phenomena in nuclear physics is the occurrence of neutron halos and neutron skins in very neutron rich atomic nuclei. Thick neutron skins and halos, not yet evidenced in medium mass nuclei, - would be unique low-density neutron matter accessible in the laboratory. Nuclear shell structure is also known to change with the number of protons and neutrons. The nuclear structure of very heavy nuclei at and above Z=100 is barely known, and the - existence of new long-lived heavy isotopes is still an open question. The above fundamental phenomena related to the unbalance of neutron and protons in unstable nuclei are essential to understand the complex nature of nuclei and related - astrophysical processes. - - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - PUMA - - - ERC-2016-COG - - - 726276 - - - - - KOBENHAVNS UNIVERSITET - KOBENHAVNS UNIVERSITET - - - EUR 1 999 909 - - - Criminal Entanglements.A new ethnographic approach to transnational organised crime. - - - EUR 1 999 909 - - - Denmark - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Linked to terrorism, moral breakdown, and societal decay, Transnational Organised Crime (TOC) has come to embody current global anxieties as a figure of fear and cause of disquiet. Yet despite its central position on the - social and political radar, our knowledge of it remains limited and fragmentary. Quantitative analyses may have identified the scale of the problem, but its underlying socio-cultural logic and practices remain under-researched and largely obscure. - TOC is on the rise, and we need better insights into how it develops and expands, who engages in it and why, and how it is linked to and embedded in social networks that straddle countries and contexts. - - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Denmark - - - CRIMTANG - - - ERC-2016-COG - - - 725194 - - - - - UNIVERSITY COLLEGE LONDON - UNIVERSITY COLLEGE LONDON - - - EUR 1 471 530 - - - The Politics of Climate Change Loss and Damage - - - EUR 1 471 530 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The way in which normative principles (“norms”) matter in world politics is now a key area of international relations research. Yet we have limited understanding of why some norms emerge and gain traction globally whereas - others do not. The politics of loss and damage related to climate change offers a paradigm case for studying the emergence of - and contestation over - norms, specifically justice norms. The parties to the UN Framework Convention on Climate Change - (UNFCCC) have recently acknowledged that there is an urgent need to address the inevitable, irreversible consequences of climate change. Yet within this highly contested policy area - which includes work on disaster risk reduction; non-economic - losses (e.g. loss of sovereignty); finance and climate-related migration - there is little consensus about what loss and damage policy means or what it requires of the global community, of states and of the (current and future) victims of climate - change. Relying on an interdisciplinary theoretical approach and an ethnographic methodology that traverses scales of governance, my project - The Politics of Climate Change Loss and Damage (CCLAD) - will elucidate the conditions under which a norm - is likely to become hegemonic, influential, contested or reversed by introducing a new understanding of the fluid nature of norm-content. I argue that norms are partly constituted through the practices of policy-making and implementation at the - international and national level. The research will examine the micro-politics of the international negotiations and implementation of loss and damage policy and also involves cross-national comparative research on domestic loss and damage policy - practices. Bringing these two streams of work together will allow me to show how and why policy practices shape the evolution of climate justice norms. CCLAD will also make an important methodological contribution through the development of political - ethnography and “practice-tracing” methods. - - 2023-04-30, Grant Agreement signed - - - 2018-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - CCLAD - - - ERC-2017-STG - - - 755753 - - - - - THE HEBREW UNIVERSITY OF JERUSALEM - THE HEBREW UNIVERSITY OF JERUSALEM - - - EUR 1 500 000 - - - Decoding the Epigenomic Regulatory Code by the Use of Single Cell Technologies - - - EUR 1 500 000 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Chromatin regulators adjust genome functions by modifying chromatin states. Comprehensive characterization of chromatin states, associations of chromatin regulators, and expression profiles is crucial for investigating: - 1.Cellular differentiation triggers. 2.The nature of the underlying chromatin regulatory mechanisms. 3.The effect of cellular heterogeneity, and 4. How chromatin affects mRNA expression. Mapping chromatin states by sequencing immunoprecipitated - chromatin (ChIP-seq) provides an extraordinary resource for studying cellular states. However, a major shortcoming is that the profiles reflect a composite average over the studied cell population, concealing important information about the - underlying subpopulations. To address this hurdle, I pioneered Drop-Seq, a novel drop based microfluidic technology for single cell ChIP-seq and RNA-seq. Applying the technique to thousands of embryonic stem (ES) cells, we identified a spectrum of - sub-populations defined by differences in chromatin signatures of pluripotency and differentiation priming. However, despite initial progress, the extent and significance of chromatin-state heterogeneity and its relationship with mRNA expression - remain largely uncharted. The central aim of this proposal is to develop a novel framework to systematically characterize cell-to-cell variability at the epigenomic level. Our approach will include the development of technology enabling ChIP-seq and - RNA-seq on the same cell. We will also exploit drop-based microfluidics to develop a robust CRISPR/Cas9-based approach to assess single and multiple perturbations. Finally, we will apply these innovative technologies to questions about cellular - heterogeneity and epigenomic regulation during early differentiation of ES cells. This proposal will reveal the function and interplay between chromatin regulators, histone marks and transcription events, and shed light on the underlying regulation - leading to cell fate decisions. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Israel - - - SC-EpiCode - - - ERC-2016-STG - - - 715260 - - - - - AGENCE NATIONALE DE LA RECHERCHE - FONDS ZUR FÖRDERUNG DER WISSENSCHAFTLICHEN FORSCHUNG - FONDS NATIONAL DE LA RECHERCHE SCIENTIFIQUE - BULGARIAN NATIONAL SCIENCE FUND - SCHWEIZERISCHER NATIONALFONDS ZUR FORDERUNG DER WISSENSCHAFTLICHEN FORSCHUNG - TECHNOLOGICKA AGENTURA CESKE REPUBLIKY - SIHTASUTUS EESTI TEADUSAGENTUUR - MINISTERIO DE ECONOMIA, INDUSTRIA Y COMPETITIVIDAD - SUOMEN AKATEMIA - AN TUDARAS UM ARD OIDEACHAS - MINISTERO DELL'ISTRUZIONE, DELL'UNIVERSITA' E DELLA RICERCA - Lietuvos mokslo taryba - NARODOWE CENTRUM NAUKI - Unitatea Executiva pentru Finantarea Invatamantului Superior, a Cercetarii, Dezvoltarii si Inovarii - SLOVENSKA AKADEMIA VIED - TURKIYE BILIMSEL VE TEKNOLOJIK ARASTIRMA KURUMU - THE ENGINEERING AND PHYSICAL SCIENCES RESEARCH COUNCIL - - - EUR 4 500 787,50 - - - European coordinated research on long-term ICT and ICT-based scientific challenges - - - EUR 14 438 750 - - - France - Austria - Belgium - Bulgaria - Switzerland - Czech Republic - Estonia - Spain - Finland - Ireland - Italy - Lithuania - Poland - Romania - Slovakia - Turkey - United Kingdom - - - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Other - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Research Organisations - Research Organisations - Research Organisations - - "CHIST-ERA is a network of research funding organisations in Europe and beyond with programmes in ICST (Information and Communication Science and Technology), at the intersection of the FET and the ICT domains. CHIST-ERA III - aims at supporting transnational research projects addressing long-term scientific challenges in the domain of ICT or at the interface between this and other domains. It also fosters the maturation of the corresponding research topics and the - structuration of the corresponding communities. Another goal is to encourage Open Science best practices. In the framework of CHIST-ERA III, two joint transnational calls are planned (CHIST-ERA Calls 2017 and 2018), each covering two topics. The two - topics for Call 2017 are ""Object recognition and manipulation by robots: data sharing and experiment reproducibility"" and ""Industrial big data and process modelling for smart factories"". The two topics for Call 2018 will be decided toward the end - of 2017." - - 2022-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.2."> - - - FETPROACT-02-2017 - FET ERANET Cofund - - - ERA-NET-Cofund - ERA-NET Cofund - - - France - - - CHIST-ERA III - - - FETPROACT-2017 - - - 768977 - - - - - UPPSALA UNIVERSITET - UPPSALA UNIVERSITET - KOBENHAVNS UNIVERSITET - - - EUR 1 145 879 - - - Dynamics of Supersymmetry in Curved Space - - - EUR 1 145 879 - - - Sweden - Sweden - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Quantum field theory provides a theoretical framework to explain quantitatively natural phenomena as diverse as the fluctuations in the cosmic microwave background, superconductivity, and elementary particle interactions in - colliders. Even if we use quantum field theories in different settings, their structure and dynamics are still largely mysterious. Weakly coupled systems can be studied perturbatively, however many natural phenomena are characterized by strong - self-interactions (e.g. high T superconductors, nuclear forces) and their analysis requires going beyond perturbation theory. Supersymmetric field theories are very interesting in this respect because they can be studied exactly even at strong - coupling and their dynamics displays phenomena like confinement or the breaking of chiral symmetries that occur in nature and are very difficult to study analytically. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Sweden - - - CurvedSusy - - - ERC-2014-STG - - - 639220 - - - - - UPPSALA UNIVERSITET - UPPSALA UNIVERSITET - - - EUR 1 497 059 - - - Molecularly defined models of human childhood brain tumors - - - EUR 1 497 059 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - MYC proteins like MYC and MYCN are transcription factors that are mis-regulated in more than half of all types of human cancer including medulloblastoma, the most common brain malignancy in children. The two main challenges - that can guide research in the field of pediatric brain tumors is improving survival and reducing long-term detriments due to treatment toxicities, especially from craniospinal radiotherapy. Medulloblastoma is suggested to originate from specific - cells in the small brain, cerebellum. These brain tumors have recently been classified into four distinct molecular subgroups and subgroup-specific driver genes have been suggested. However, the precise role of such drivers in tumor initiation and - their importance in specifying particular subgroups has not been sufficiently evaluated in proper cells of medulloblastoma origin. - - 2020-04-30, ongoing project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Sweden - - - Medulloblastoma - - - ERC-2014-STG - - - 640275 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - - - EUR 171 792,60 - - - Gravity and Kinematic Space - - - EUR 171 792,60 - - - United Kingdom - United States - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The experienced researcher, Dr. Benjamin Mosk, wants to investigate a description of gravity in terms of non-local degrees of freedom. This approach is motivated by the AdS/CFT correspondence and the recent progress made by - Dr. Mosk and his collaborators on the subject of kinematic space, the space of totally geodesic sub manifolds of Anti de Sitter (AdS) space. Dr. Mosk proposes to generalize the idea of kinematic space and the description of dynamical fields on this - space to more general classical geometries, starting with the AdS-Schwarzschild geometry. The scientific objective of this project is to make progress towards a fundamental description of gravity at the non-classical level, which is arguably the - largest open question in theoretical physics. - - 2019-09-30, Grant Agreement terminated - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - MOSK - - - H2020-MSCA-IF-2016 - - - 750838 - - - - - THE UNIVERSITY OF BIRMINGHAM - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - THE UNIVERSITY OF NOTTINGHAM - UNIVERSITY OF YORK - WEIZMANN INSTITUTE OF SCIENCE - UNIVERSITE D'AIX MARSEILLE - DANMARKS TEKNISKE UNIVERSITET - JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN - OXFORD INSTRUMENTS INDUSTRIAL PRODUCTS LIMITED - UNIVERSITAETSKLINIKUM FREIBURG - Rotem Industries Ltd. - CORTECNET - - - EUR 3 960 039,96 - - - EUROPOL - - - EUR 3 960 039,96 - - - United Kingdom - United Kingdom - United Kingdom - United Kingdom - Israel - France - Denmark - Germany - United Kingdom - Germany - Israel - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - NMR and MRI play unique roles in contemporary Science, from Physics, Chemistry and Biology, to clinical research and diagnosis. Despite its irreplaceable role, further progress in NMR and MRI is hampered by sensitivities that - are much lower than those of alternatives such as mass-spec, or PET. The prospects of solving this problem by “bigger machines” are uncertain and of poor return, given the high maturity already achieved by NMR/MRI. This ETN challenges this status - from an untapped perspective, combining NMR/MRI with nuclear hyperpolarization eliciting signals that surpass those currently available by up to 50,000x. Focus is placed on two particular approaches, dynamic nuclear polarization and - para-hydrogen-driven polarization, exhibiting the highest potential for biophysical, metabolomic, pre-clinical and clinical research. To maximize these “supersignals” we assembled leading experts in the physics and engineering of magnetic resonance, - in the synthetic chemistry essential for the success of these methods, in the uses of NMR to structural/cell biology, and in preclinical and clinical MRI applications. Guiding this assembling is the conception that only by teaming together key areas - of expertise, can hyperpolarisation’s promises be realized. In addition to fostering synergies among experts from academia and industry, EUROPOL will provide frontier training for ESRs in all the topics underlying the advancement of MR. This will - include advanced physics, new instruments and forms of exploiting NMR/MRI’s hyperpolarisation, biophysical NMR, screening of healthy and diseased metabolomes, expanded portfolios of substrates to be targeted by in vivo MR, ancillary in cell and - system biology explorations clarifying the nature of the metabolic phenomena, and in vivo hyperpolarisation strategies in MRI. This ETN is unparalleled in scope, breadth and potential for synergies. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - EUROPOL - - - H2020-MSCA-ITN-2014 - - - 642773 - - - - - ROSKILDE UNIVERSITET - GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER - UPPSALA UNIVERSITET - GROUPE SUP DE CO MONTPELLIER - UNIVERSIDAD POMPEU FABRA - INSTITIUID TEICNEOLAIOCHTA BHAILE ATHA CLIATH - INSTITUTO DE GEOGRAFIA E ORDENAMENTO DO TERRITORIO DA UNIVERSIDADE DELISBOA - UNIVERSITY OF EAST LONDON - THE UNIVERSITY OF BIRMINGHAM - STICHTING THE NETWORK UNIVERSITY - STOCKHOLMS UNIVERSITET - SWEDISH ETHIOPIAN CHAMBER OF COMMERCE - UNIVERSITY OF STRATHCLYDE - SYDDANSK UNIVERSITET - - - EUR 571 500 - - - DiasporaLink - - - EUR 571 500 - - - Denmark - Germany - Sweden - France - Spain - Ireland - Portugal - United Kingdom - United Kingdom - Netherlands - Sweden - Sweden - United Kingdom - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - Higher or Secondary Education Establishments - Other - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - DiasporaLink is a 4-year exchange program between 24 universities and research institutes representing EU, the Americas, Africa and Australia and will investigate, evaluate and facilitate transnational diaspora - entrepreneurship, TDE as driver of development and wealth creation in countries of origin and residence. - - - 2019-01-31, ongoing project - - - 2015-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Denmark - - - DiasporaLink - - - H2020-MSCA-RISE-2014 - - - 645471 - - - - - "NATIONAL CENTER FOR SCIENTIFIC RESEARCH ""DEMOKRITOS""" - NATIONAL OBSERVATORY OF ATHENS - HELLENIC CENTRE FOR MARINE RESEARCH - ETHNIKO IDRYMA EREVNON - ATHINA-EREVNITIKO KENTRO KAINOTOMIAS STIS TECHNOLOGIES TIS PLIROFOFORIAS, TON EPIKOLNONION KAI TIS GNOSIS - IDRIMA MEIZONOS ELLINISMOU - EPISTIMI EPIKOINONIA - - - EUR 160 000 - - - Researcher's Night: meeting science and your next door scientist - - - EUR 160 000 - - - Greece - Greece - Greece - Greece - Greece - Greece - Greece - - - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Other - - A diverse team of experts in scientific research and science communication from leading Research Institutes and Educational Organizations located in the Athens Metropolitan area is formed to organize the Researcher's Night - activities for the years 2014 and 2015. By adopting the concept “Science invites People”, we propose a large scale REN, in 2014, at NCSR Demokritos, the largest Science Research campus in Attica, and a similar event in 2015, at IME a multiplex where - science meets entertainment and exploration, organized by the National Observatory of Athens . - - - 2015-10-31, closed project | - - - 2014-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.5."> - - - MSCA-NIGHT-2014 - European Researchers' Night (NIGHT) - - - CSA - Coordination and support action - - - Greece - - - REN-ATHENS - - - H2020-MSCA-NIGHT-2014 - - - 633335 - - - - - KOBENHAVNS UNIVERSITET - TURUN YLIOPISTO - FRIEDRICH-SCHILLER-UNIVERSITAT JENA - ZOOLOGISCHES FORSCHUNGSMUSEUM ALEXANDER KOENIG - NATURHISTORISCHES MUSEUM - PENSOFT PUBLISHERS - Era7 Information Technologies SL - UNIVERZITA KARLOVA - NATURHISTORISKA RIKSMUSEET - DECURIA AB - SAVANTIC AB - LUNDS UNIVERSITET - - - EUR 3 885 250,68 - - - BIG4 - Biosystematics, Informatics and Genetics of the big 4 insect groups: training tomorrow's researchers and entrepreneurs - - - EUR 3 885 251,22 - - - Denmark - Finland - Germany - Germany - Austria - Bulgaria - Spain - Czech Republic - Sweden - Sweden - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - BIG4 is a global network to amalgamate the cutting edge methods of genomics, phylogenetics, informatics, taxonomy, semantic biodiversity publishing and citizen science, into highly competitive cross-disciplinary training - programme for 15 ESRs with a stronghold in biosystematics. These 15 future leaders will extend the exploration of the four biggest groups of living organisms in a more forward looking way than has been attempted before. The urgent focus on the “big - four” insect groups, i.e. Coleoptera (beetles), Hymenoptera (wasps, ants and bees), Diptera (flies and mosquitoes), and Lepidoptera (butterflies and moths) is justified by the super abundance of this form of Life, and by the growing need by science - and society to make better use of the enormous potential hidden in their biological diversity. BIG4 aims [1] to gain a robust systematic knowledge that explains the evolutionary origin, diversification, past and present distributions of living - organisms, [2] to model their future dispersal and [3] to predict the traits of species that are yet unknown. Additionally, BIG4 strives for [4] implementing organismal features into engineering, medicine, agricultural or environmental solutions, the - insect flight mechanics and more effective pollination to mention just a few. Such knowledge is in a particularly high demand in respect of the four biggest insects groups comprising the most important model organisms, the most dangerous pests or - disease vectors, the most abundant invasive species and the most fragile entire species communities undergoing extinction due to habitat destruction. By integrating academia with the business and public sectors, BIG4 will greatly increase services - and beneficial products provided by the biosystematics as a science. BIG4 will place insect mega-diversity as a powerful service for economic and societal needs such as environmental monitoring, biological control, biomedicine, or ecological farming. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Denmark - - - BIG4 - - - H2020-MSCA-ITN-2014 - - - 642241 - - - - - INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE - ABERYSTWYTH UNIVERSITY - AGENZIA LUCANA DI SVILUPPO E DI INNOVAZIONE IN AGRICOLTURA - ASA ADVANCED SOLUTIONS ACCELERATOR - AARHUS UNIVERSITET - COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION - STICHTING WAGENINGEN RESEARCH - FORSCHUNGSZENTRUM JULICH GMBH - LEIBNIZ - INSTITUT FUER PFLANZENGENETIK UND KULTURPFLANZENFORSCHUNG - HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH - INSTYTUT GENETYKI ROSLIN POLSKIEJ AKADEMI NAUK - INRA TRANSFERT S.A. - MAGYAR TUDOMANYOS AKADEMIA SZEGEDIBIOLOGIAI KUTATOKOZPONT - PHENOSPEX BV - SLOVENSKA POLNOHOSPODARSKA UNIVERSITA V NITRE (SLOVAK AGRICULTURAL UNIVERSITY IN NITRA) - UNIVERSITE CATHOLIQUE DE LOUVAIN - KOBENHAVNS UNIVERSITET - HELSINGIN YLIOPISTO - THE UNIVERSITY OF NOTTINGHAM - VIB - VSN INTERNATIONAL LTD - WAGENINGEN UNIVERSITY - - - EUR 9 999 999,50 - - - European Plant Phenotyping Network 2020 - - - EUR 10 220 249,50 - - - France - United Kingdom - Italy - France - Denmark - Australia - Netherlands - Germany - Germany - Germany - Poland - France - Hungary - Netherlands - Slovakia - Belgium - Denmark - Finland - United Kingdom - Belgium - United Kingdom - Netherlands - - - Research Organisations - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - EPPN2020 will provide European public and private scientific sectors with access to a wide range of state-of-the-art plant phenotyping facilities, techniques and methods. It will aid the community in progressing towards - excellence across the whole phenotyping pipeline, involving sensors and imaging techniques, data analysis in relation to environmental conditions, data organization and storage, data interpretation in a biological context and meta-analyses of - experiments. It builds upon the starting community project EPPN and will coordinate its activities with the ESFRI infrastructure EMPHASIS and with national programs. - - 2021-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.2."> - - - INFRAIA-01-2016-2017 - Integrating Activities for Advanced Communities - - - RIA - Research and Innovation action - - - France - - - EPPN2020 - - - H2020-INFRAIA-2016-1 - - - 731013 - - - - - UNIVERSITEIT VAN AMSTERDAM - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - DEUTSCHES KREBSFORSCHUNGSZENTRUM - UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA - ACADEMISCH ZIEKENHUIS GRONINGEN - MAGYAR TUDOMANYOS AKADEMIA SZEGEDIBIOLOGIAI KUTATOKOZPONT - Epiontis GmbH - CLINICAGENO LIMITED - - - EUR 2 797 697,16 - - - Epigenetic regulation of endocrine therapy resistance in breast cancer: A systems medicine approach to predict treatment outcome - - - EUR 2 797 697,16 - - - Netherlands - United Kingdom - Germany - Italy - Netherlands - Hungary - Germany - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The mission of EpiPredict is to train a multidisciplinary cohort of young researchers in a new approach to fully exploit the epigenetics of complex diseases. The 12 early-stage researchers (ESRs) will focus on a narrowly - defined case, Tamoxifen-induced resistance in Estrogen Receptor positive (ER+) breast cancer, considering five resistance interacting pathways. Given the frequent Tamoxifen treatment failure, resistance prevention and reversal is an urgent clinical - problem that is central in EpiPredict. The EpiPredict intersectorial training programme employs a timely systems medicine approach combining next-generation systematic epigenetic, gene/protein profiling with innovative gene-specific epigenetic - interference technologies for iterative computational modelling. Together the ESRs will identify key epigenetic changes underlying Tamoxifen induced resistance. This will provide an important step towards diagnostic markers/tools to predict treatment - outcome and response monitoring setting the scene for breast cancer personalized medicine. The fellows will be trained by experts from 6 academic and 2 non-academic beneficiaries and 7 partner organizations (1 academic, 6 non-academic including - industrial/socio-public parties) and 5 visiting scientists, from fields ranging from epigenetics to both computation and medicine. Strong involvement of the private sector ensures exploitation of EpiPredict achievements and exposure of the ESRs to an - entrepreneurial mindset. - - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Netherlands - - - EpiPredict - - - H2020-MSCA-ITN-2014 - - - 642691 - - - - - UNIVERSITE LIBRE DE BRUXELLES - THE UNIVERSITY OF EXETER - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - KONGSBERG MARITIME CONTROS GMBH - STICHTING DELTARES - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - UNIVERSITY OF BRISTOL - UPPSALA UNIVERSITET - - - EUR 3 112 980,61 - - - Carbon Cascades from Land to Ocean in the Anthropocene - - - EUR 3 112 980,61 - - - Belgium - United Kingdom - France - Germany - Netherlands - Germany - United Kingdom - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - C-CASCADES will produce a new generation of young scientists trained to span the boundaries between disciplines and with the skill-sets required to address one of the grand research challenges of the 21st century: the role of - the carbon cycle in regulating Earth’s climate. Training will be embedded within and guided by the overriding science objective of the programme, to make a breakthrough in understanding the transfer of carbon between land and ocean at planetary scale - and the consequences for atmospheric CO2 and climate. This will require cutting-edge research and innovation to permit characterization of the transport, transformation and ultimate fate of carbon in rivers, lakes and coastal waters and their - representation in Earth System Models. This will allow a better quantification of the fluxes of greenhouse gases (primarily CO2 and CH4) exchanged with the atmosphere and their impacts on the climate system. The closely related training objective is - to engage the next generation of Earth system scientists in an integrated, cutting-edge and highly relevant joint research programme. The research undertaken will capture technological innovation in sensor development; advance mechanistic - understanding of the carbon transformations that occur during lateral transfer between land and ocean; embed this understanding in enhanced catchment, regional and global-scale models; and, assess quantitatively carbon transfer fluxes and carbon - transformations along the land to ocean aquatic continuum at the global scale, from terrestrial ecosystems to the open ocean via rivers, lakes and coastal waters. The suite of C-CASCADES models will be progressively improved during the course of the - project and evaluated against observations. These models will be applied to disentangle human impacts (e.g. land-use, river management, wastewater production, CO2, climate) on the land-to-ocean carbon cycle, for the historical period and future IPCC - climate scenarios. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Belgium - - - C-CASCADES - - - H2020-MSCA-ITN-2014 - - - 643052 - - - - - ISRAEL NATIONAL MUSEUM OF SCIENCE, TECHNOLOGY AND SPACE DANIEL AND MATILDE RECANATI CENTER - MIGAL GALILEE RESEARCH INSTITUTE LTD - WEIZMANN INSTITUTE OF SCIENCE - TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY - Bloomfield Science Museum Jerusalem (BSMJ) - THE HEBREW UNIVERSITY OF JERUSALEM - TEL AVIV UNIVERSITY - SAMI SHAMOON COLLEGE OF ENGINEERING(R.A.) FRIENDLY SOCIETY - UNIVERSITY OF HAIFA - THE OPEN UNIVERSITY* - BAR ILAN UNIVERSITY - ISRAEL OCEANOGRAPHIC AND LIMNOLOGICAL RESEARCH LIMITED - - - EUR 300 000 - - - European Researchers' Night 2014 and 2015 in Israel - - - EUR 808 050 - - - Israel - Israel - Israel - Israel - Israel - Israel - Israel - Israel - Israel - Israel - Israel - Israel - - - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - Following previous eight years of successful implementation of European Researchers' Night in Israel we will have: - - 2015-10-31, closed project - - - 2014-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.5."> - - - MSCA-NIGHT-2014 - European Researchers' Night (NIGHT) - - - CSA - Coordination and support action - - - Israel - - - ERNI2014 - - - H2020-MSCA-NIGHT-2014 - - - 633277 - - - - - STICHTING KATHOLIEKE UNIVERSITEIT - UNIVERSITEIT UTRECHT - UNIVERSITEIT GENT - KING'S COLLEGE LONDON - BIRKBECK COLLEGE - UNIVERSITY OF LONDON - KAROLINSKA INSTITUTET - UPPSALA UNIVERSITET - ISTITUTO SUPERIORE DI SANITA - UNIWERSYTET WARSZAWSKI - VICARIOUS PERCEPTION TECHNOLOGIES BV - - - EUR 3 888 945,36 - - - Integrated view on disruptions of early brain development - - - EUR 3 888 945,36 - - - Netherlands - Netherlands - Belgium - United Kingdom - United Kingdom - Sweden - Sweden - Italy - Poland - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Early onset neurodevelopmental disorders such as autism spectrum disorders (ASD) and attention-deficit hyperactivity disorder (ADHD) are rather common, and affect more than 30 million children in Europe. The disorders carry a - huge burden to the patients and their families and to society in general. This burden is linked to their chronic course and the absence of curative treatments. These neurodevelopmental disorders are thought to result from the disruption of normal - brain development and related neurobiological mechanisms during the prenatal and early postnatal period. Recent advances in technology, infrastructure and analytic tools allow us now to identify these disruptions in brain development in the prenatal - and early postnatal period, examine how this compromises the development of key social, attentional, motor and cognitive skills, and help understanding of the mechanisms that lead to neurodevelopmental disorders. This will facilitate developing new - approaches to early detection, diagnosis and treatment. BRAINVIEW ETN provides a multidisciplinary and intersectoral (academia, companies, patient organizations) network environment in which cutting-edge science is combined with training young - researchers in such an approach. - - 2018-12-31, ongoing project | - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Netherlands - - - BRAINVIEW - - - H2020-MSCA-ITN-2014 - - - 642996 - - - - - UNIVERSITE DE BOURGOGNE - UNIVERSITE DE FRANCHE-COMTE - Centre de Culture Scientifique et Technique d'Angers Terre des Sciences Association - ASSOCIATION CAP SCIENCES-CENTRE DE CULTURE SCIENTIFIQUE TECHNIQUE ET INDUSTRIELLE BORDEAUX-AQUITAINE - BREST'AIM SA - UNIVERSITE DU MANS - FONDATION PARTENARIALE DE LUNIVERSITE DE LIMOGES - COMUNAUTE D'UNIVERSITES ET ETABLISSEMENTS UNIVERSITE DE LYON - UNIVERSITE DE LORRAINE - ASSOCIATION TRACES THEORIES ET REFLEXIONS SUR L APPRENDRE LA COMMUNICATION ET L EDUCATION SCIENTIFIQUES - UNIVERSITE FEDERALE DE TOULOUSE MIDI-PYRENEES - COMMUNAUTE D'UNIVERSITE ET D'ETABLISSEMENTS UNIVERSITE FEDERALE DE TOULOUSE MIDI-PYRENEES - - - EUR 421 200 - - - RESEARCHER'S NIGHT IN FRANCE - - - EUR 1 045 075 - - - France - France - France - France - France - France - France - France - France - France - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Other - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - "ERN has gained momentum in France. Thus, the Ministry of Research has decided to open its great ""Science Fair"" with the ERN, which is a recognition of the quality of the event and significantly develops its reputation and - visibility. Therefore, we have set up a programme with distinctive visible features and a high level of consistency throughout the French territory for the 2014 and 2015 editions. - - 2015-11-30, closed project - - - 2014-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.5."> - - - MSCA-NIGHT-2014 - European Researchers' Night (NIGHT) - - - CSA - Coordination and support action - - - France - - - EXPERIM - - - H2020-MSCA-NIGHT-2014 - - - 633263 - - - - - UNIVERSITY COLLEGE LONDON - FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA - DEUTSCHES ZENTRUM FUR NEURODEGENERATIVE ERKRANKUNGEN EV - ITA-SUOMEN YLIOPISTO - LEIBNIZ-INSTITUT FUER NEUROBIOLOGIE - INSTYTUT BIOLOGII DOSWIADCZALNEJ IM. M. NENCKIEGO POLSKIEJ AKADEMII NAUK - UNIVERSITEIT ANTWERPEN - Academisch Medisch Centrum bij de Universiteit van Amsterdam - IPROTEOS SL - UNIVERSITE D'AIX MARSEILLE - - - EUR 3 047 025,60 - - - The Extracellular Matrix in Epileptogenesis - - - EUR 3 047 025,60 - - - United Kingdom - Italy - Germany - Finland - Germany - Poland - Belgium - Netherlands - Spain - France - - - Higher or Secondary Education Establishments - Research Organisations - Chiara Andreoli - Tel.: +3901071781854 - Fax: +39 010 7170817 - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - Over 50 million people worldwide have epilepsy and 30% are resistant to our present therapies. Epilepsy, therefore, comprises a major burden to society and so there is a pressing need for new approaches to treatment. The brain - extracellular matrix (ECM) plays a critical role in governing brain excitability and function. Although research into the role of the ECM in neuronal signalling and network function has advanced considerably in recent years, its full translational - potential has yet to be realised. There is growing evidence for a major role of the ECM in epilepsy including the association between ECM protein mutations and epilepsy, changes in the ECM and associated proteins during the development of epilepsy - and the strong association between the ECM and brain diseases associated with epilepsy including stroke, traumatic brain injury, neurodegeneration and autism. - - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - ECMED - - - H2020-MSCA-ITN-2014 - - - 642881 - - - - - STICHTING KATHOLIEKE UNIVERSITEIT - UPPSALA UNIVERSITET - BIRKBECK COLLEGE - UNIVERSITY OF LONDON - LANCASTER UNIVERSITY - UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA - TWENTE MEDICAL SYSTEMS INTERNATIONAL B.V. - ARTINIS MEDICAL SYSTEMS BV - SMART EYE AKTIEBOLAG - QUALISYS AB - - - EUR 3 685 408,56 - - - Mobile Technology for Infant Social-Cognitive Neuroscience: Interdisciplinary Training Networkfor Innovative Infancy Research - - - EUR 3 685 408,56 - - - Netherlands - Sweden - United Kingdom - United Kingdom - Italy - Netherlands - Netherlands - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - "Recent international reports emphasize that the first three years of children’s life have more impact on their future outcomes than any other period during life. It is therefore essential that we have a thorough understanding - of early social and cognitive development. In the past, experimental research that has fed our knowledge on early development studied infants within restricted, artificial laboratory contexts. However, only by studying children who are actively - engaging in natural interaction with their social and physical environment, we can acquire ecologically valid, robust information about their social and cognitive development. It is thus essential to move experimental infancy research towards more - natural situations. In doing so, MOTION will train a new generation of highly-skilled experts in the field of early development. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Netherlands - - - MOTION - - - H2020-MSCA-ITN-2017 - - - 765298 - - - - - EUROPEAN MOLECULAR BIOLOGY LABORATORY - STAZIONE ZOOLOGICA ANTON DOHRN - UNIVERSITETET I BERGEN - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSITY COLLEGE LONDON - THE UNIVERSITY OF EXETER - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - UPPSALA UNIVERSITET - MUSEUM FUR NATURKUNDE - LEIBNIZ-INSTITUT FUR EVOLUTIONS- UND BIODIVERSITATSFORSCHUNG AN DER HUMBOLDT-UNIVERSITAT ZU BERLIN - GENOMIX4LIFE SRL - BLACKTRACE HOLDINGS LIMITED - - - EUR 3 818 591,07 - - - Animal evolution from a cell type perspective: multidisciplinary training in single-cell genomics, evo-devo and in science outreach - - - EUR 3 818 591,07 - - - Germany - Italy - Norway - France - United Kingdom - United Kingdom - Germany - Sweden - Germany - Italy - United Kingdom - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - One of the first events in the evolution of multicellular animals was the differentiation of cells into distinct types with different roles. Starting from their most simple multicellular ancestors, the cells that compose - animal bodies have become increasingly diverse; each cell type distinguished by the unique set of genes it expresses. This increase in diversity of cell types over evolutionary time is recapitulated in the process of development during which a single - undifferentiated cell - the fertilised egg - divides and its progeny differentiate into the countless cell types of the adult body. Currently we do not even know how many distinct cell types animals posses, how new cell types arise in evolution, how - many are in common between different animal groups and how many unique cell types have evolved in different lineages. Our aim in EvoCELL is to lay the foundation for a new branch of evo-devo focussing on cell types. We will study these fundamental - questions in animal evolution and development using a new technology - single cell sequencing - which we will for the first time employ outside of lab models to sample the great diversity of animal phyla. Europe is home to world-leading expertise in - evo-devo and single-cell genomics, but research and training efforts are as yet uncoordinated and their potential for synergy underexplored. EvoCELL will harness and expand this European excellence by training a new generation of multidisciplinary - scientists skilled in exploring the vast breadth of animal differentiation. We will jointly sample data from all major animal lineages, richly represented in the biodiversity of European waters, and develop new tools for comparative analyses, through - which we will together pioneer three branches of cell evo-devo: evolution of stem cells; emergence of animal life cycles, and the stunning diversity of neural cell types. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - EvoCELL - - - H2020-MSCA-ITN-2017 - - - 766053 - - - - - ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON - GEORG-AUGUST-UNIVERSITAT GOTTINGENSTIFTUNG OFFENTLICHEN RECHTS - CONSIGLIO NAZIONALE DELLE RICERCHE - UNIWERSYTET WARSZAWSKI - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH - ATHINA-EREVNITIKO KENTRO KAINOTOMIAS STIS TECHNOLOGIES TIS PLIROFOFORIAS, TON EPIKOLNONION KAI TIS GNOSIS - UNIVERSITAET BIELEFELD - UNIVERSIDADE DO MINHO - STICHTING EIFL.NET - UNIVERSITEIT GENT - UNIVERSITETET I OSLO - COAR E.V. - STICHTING LIBER - COOPERACION LATINOAMERICANA DE REDES AVANZADAS - UNIVERSITEIT VAN AMSTERDAM - EUROPEAN MOLECULAR BIOLOGY LABORATORY - UNIVERSITAET BREMEN - RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN - JISC LBG - STICHTING SURF - KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW - TECHNISCHE UNIVERSITEIT DELFT - UNIVERSITAT WIEN - INSTITUTE OF MATHEMATICS AND INFORMATICS AT THE BULGARIAN ACADEMY OF SCIENCE - RUDER BOSKOVIC INSTITUTE - UNIVERSITY OF CYPRUS - VYSOKA SKOLA BANSKA - TECHNICKA UNIVERZITA OSTRAVA - SYDDANSK UNIVERSITET - TARTU ULIKOOL - HELSINGIN YLIOPISTO - CONSORTIUM UNIVERSITAIRE DE PUBLICATIONS NUMERIQUES COUPERIN - UNIVERSITAT KONSTANZ - ETHNIKO IDRYMA EREVNON - DEBRECENI EGYETEM - LANDSPITALI UNIVERSITY HOSPITAL - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - CINECA CONSORZIO INTERUNIVERSITARIO - LATVIJAS UNIVERSITATE - KAUNO TECHNOLOGIJOS UNIVERSITETAS - UNIVERSITE DU LUXEMBOURG - UNIVERSITA TA MALTA - Sarminfo SRL - UNIVERZITET U BEOGRADU - CENTRUM VEDECKO TECHNICKYCH INFORMACII SLOVENSKEJ REPUBLIKY - UNIVERZA V LJUBLJANI - FUNDACION ESPANOLA PARA LA CIENCIA Y LA TECNOLOGIA - KUNGLIGA BIBLIOTEKET - UNIVERSITAT ZURICH - IZMIR INSTITUTE OF TECHNOLOGY - UNIVERSITY COLLEGE LONDON - - - EUR 13 000 000 - - - Open Access Infrastructure for Research in Europe 2020 - - - EUR 13 132 500 - - - Greece - Germany - Italy - Poland - Switzerland - Greece - Germany - Portugal - Netherlands - Belgium - Norway - Germany - Netherlands - Uruguay - Netherlands - Germany - Germany - Germany - United Kingdom - Netherlands - Netherlands - Netherlands - Austria - Bulgaria - Croatia - Cyprus - Czech Republic - Denmark - Estonia - Finland - France - Germany - Greece - Hungary - Iceland - Ireland - Italy - Latvia - Lithuania - Luxembourg - Malta - Romania - Serbia - Slovakia - Slovenia - Spain - Sweden - Switzerland - Turkey - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Other - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - Other - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - OpenAIRE2020 represents a pivotal phase in the long-term effort to implement and strengthen the impact of the Open Access (OA) policies of the European Commission (EC), building on the achievements of the OpenAIRE projects. - OpenAIRE2020 will expand and leverage its focus from (1) the agents and resources of scholarly communication to workflows and processes, (2) from publications to data, software, and other research outputs, and the links between them, and (3) - strengthen the relationship of European OA infrastructures with other regions of the world, in particular Latin America and the U.S. Through these efforts OpenAIRE2020 will truly support and accelerate Open Science and Scholarship, of which Open - Access is of fundamental importance. - - 2018-06-30, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.3."> - - - EINFRA-2-2014 - e-Infrastructure for Open Access - - - RIA - Research and Innovation action - - - Greece - - - OpenAIRE2020 - - - H2020-EINFRA-2014-1 - - - 643410 - - - - - UNIVERSITA DEGLI STUDI DI SASSARI - - - EUR 168 277,20 - - - Urbanization in China's South-western Borderlands. The case of Jinghong, Xiguangbanna - - - EUR 168 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - This interdisciplinary research project aims to study urbanization in China’s non-metropolitan and non-industrial ethnic-diverse border regions under post-socialism. Literature on urbanization in China focuses mainly on - traditional large metropolitan or industrial cities in the center with Han majority population, and examines either the structural or the subjective features of urban development. The complex dynamics of urbanization and power relations in the new - cities in the periphery remain understudied. The project fills this knowledge gap, by exploring how urbanization intersects with tourism growth and in-migration and affects ethnic relations in Jinghong, a fast-growing city in China’s south-western - borderlands. In Jinghong, the Han, China’s ethnic majority, have become the city’s drivers of urban and economic development, competing over land, resources and political power with long-term Dai/Tai minority ethnic residents. Unconventionally - drawing on methods of Anthropology, Urban Planning, Architecture, Urban Geography, and Sociology, this pioneering project aims at producing a theoretically and empirically innovative analysis that combines structural, socio-economic, and political - examination with an investigation of subjective and experiential aspects of urbanization, highlighting conflicts, mindsets, and prejudices in the day-to-day urban interactions between Han majority and ethnic minority citizens and the state. - - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - Italy - - - URBAN_CHINA - - - H2020-MSCA-IF-2016 - - - 748961 - - - - - UNIVERSITE DE PAU ET DES PAYS DE L'ADOUR - FUNDACIO PRIVADA INSTITUT CATALA D'INVESTIGACIO QUIMICA - TECHNISCHE UNIVERSITEIT EINDHOVEN - UPPSALA UNIVERSITET - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - UNIVERSITAET STUTTGART - UNIVERSITE DE NAMUR ASBL - SOLARONIX SA - RIVA GMBH BATTERIES - FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA - FUNDACIO EURECAT - - - EUR 3 599 025,20 - - - European School on Artificial Leaf : Electrodes Devices - - - EUR 3 599 025,20 - - - France - Spain - Netherlands - Sweden - France - Germany - Belgium - Switzerland - Germany - Italy - Spain - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Chiara Andreoli - Tel.: +3901071781854 - Fax: +39 010 7170817 - Research Organisations - - Climate change resulting from accumulation of anthropogenic carbon dioxide in the atmosphere and the uncertainty in the amount of recoverable fossil fuel reserves are driving forces for the development of renewable, - carbon-neutral energy technologies. Artificial photosynthesis appears to be an appealing approach for a sustainable energy generation as it produces “solar fuels” or commodities for chemistry in a stable and storable chemical form, from solar energy, - H2O & CO2. - - 2022-03-31, Grant Agreement signed - - - 2018-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-EJD - European Joint Doctorates - - - France - - - eSCALED - - - H2020-MSCA-ITN-2017 - - - 765376 - - - - - UPPSALA UNIVERSITET - UPPSALA UNIVERSITET - - - EUR 125 318,75 - - - Soccermatics: data for football fans and clubs - - - EUR 125 318,75 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Data plays an increasingly important role in sport, from monitoring of fitness of athletes to success statistics in baseball. In football (soccer) the team performance is more important than the performance of any one - individual. While every team has its star players, it is the ability of the team to function as a unit that is the key to its success. For the data analyst, this presents a challenge: how to measure, understand and improve team performance. My - research during an ERC funded action (IDCAB) has revolved around devising exactly this type of analysis methods. Starting with my work on measuring and understanding animal groups in the ERC action, I have gone on to develop a set of tools for - looking at the collective action on the football pitch. - - - 2019-01-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Sweden - - - SOCCERMATICS - - - ERC-2016-PoC - - - 727646 - - - - - UNIVERSITY OF LEEDS - - - EUR 183 454,80 - - - From an environmental to a resource regime? Institutional innovation for the management of Tourism and Marine Protected Areas within the Antarctic Treaty governance - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The Antarctica Treaty presents one of the most intriguing environmental regimes to international relations: its institutionalisation has intensified as much as the Treaty has been able to keep controversy away from its - governance. The current arrangement postpones, outsources or builds an ambiguous guidance towards any subject which might undermine its consensual foundation. But are these solutions able to keep the Antarctic Treaty's resilience as a regime? - Antarctic history shows that expectations towards resource activities within the region has triggered challenges to this framework. Nevertheless, Antarctic Tourism and Marine Protected Areas (MPAs) are current activities respectively outsourced and - avoided by the Treaty, despite of their direct impact on the Antarctic Treaty operation. Therefore, this proposal aims to contribute towards the Antarctic Treaty governance, proposing institutional innovations which would support the Treaty to manage - complex, multilevel and controversial activities. Based on stakeholders' assessment of the Antarctic Treaty governance on Tourism and MPAs, hybrid strategies and institutional interplay will be developed and presented for discussion to these actors. - The project expects to directly contribute for the Treaty’s resilience as a regime, to increase public awareness on Antarctic matters through open access information and engaging outreach strategies, and to develop a European perspective on Antarctic - politics. A vibrant research environment, expertise on environmental and resource regimes, and training for the researcher will be offered by the University of Leeds, enabling the development of the proposal and the boosting of the researcher’s - career as an academic and expert on Antarctic politics. Furthermore, the researcher's experience in Antarctic treaties and networking, as well as her expertise in academic research, will result into publications and partnerships, establishing a - European research legacy for Antarctic politics - - 2019-09-05, ongoing project - - - 2017-09-06 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - POLARGOV - - - H2020-MSCA-IF-2016 - - - 750745 - - - - - UNIVERSITY OF LEICESTER - PRESIDENT AND FELLOWS OF HARVARD COLLEGE - - - EUR 269 857,80 - - - Spirits of Displacement and Diaspora - - - EUR 269 857,80 - - - United Kingdom - United States - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Spirit possession cults puzzle Western observers, particularly when they appear in supposedly secular urban environments. Muslim migrants from North Africa, seeking to establish new lives in Southern Europe, have to negotiate - the continuity of such ritual practices with the constraints and expectations imposed on them by their new social contexts. But the legitimacy of these cults is contested also in their homeland, where they face increasing pressures by religious - fundamentalism. Space and its organization, especially in urban settings, play an important part in these disputes. In Morocco, spirits are thought to reside in particular places, such as tombs, sanctuaries, or street corners. How do possession cults - continue to be practiced when spirits’ spaces of residence have to be abandoned or undergo demolition? This research compares the continuities and ruptures in cult performances as the spaces that host them are affected by both forced displacement and - voluntary diasporic migration. I will observe the resettlement of a slum in Casablanca, and compare it with two Southern European neighborhoods where Moroccan practitioners of spirit cults struggle to maintain their specific version of Islam in - multicultural, post-colonial and post-secular urban settings, exposed to disruptive processes such as gentrification. By applying an ethnographic methodology to comparative urbanism, I aim to shed light on how different spatial transformations affect - ritual performances that are meant to protect communities from social disintegration. I argue that different urban policies on both sides of the Mediterranean mutually reinforce, resulting in an overall transformation of cultural practices in - transnational communities. Examining how migrants adapt localized ritual practices such as spirit possession cults to increasingly transient urban settings, furthers our understanding of the spatial and cultural dimensions that enable or prevent - integration. - - 2020-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - SDD - - - H2020-MSCA-IF-2016 - - - 752547 - - - - - SWANSEA UNIVERSITY - ALFRED-WEGENER-INSTITUT HELMHOLTZ-ZENTRUM FUR POLAR- UND MEERESFORSCHUNG - KOBENHAVNS UNIVERSITET - HELLENIC CENTRE FOR MARINE RESEARCH - UNIVERSITE LIBRE DE BRUXELLES - STICHTING DELTARES - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6 - - - EUR 2 882 898,72 - - - Bringing the paradigm for marine pelagic production into the 21st century: incorporating mixotrophy into mainstream marine research - - - EUR 2 882 898,72 - - - United Kingdom - Germany - Denmark - Greece - Belgium - Netherlands - Spain - France - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - - The conceptual basis upon which management tools for our oceans, seas and coasts have operated are out-of-date. MixITiN will train an innovative team of early stage researchers (ESRs) to develop and deploy new methodologies - for researching, monitoring and managing our marine environment according to the recently revised paradigm for marine pelagic production. Current management tools and policies operate within a paradigm that builds on a simple division functioning at - the base of the food chain leading to fisheries, between ”plant-like” phytoplankton and their main consumers, the microzooplankton. Applicants of the research programme MixITiN have shown that this plant-animal paradigm represents at the least a - gross simplification, if not a falsehood. The revised paradigm recognises that most phytoplankton and half the microzooplankton combine plant-like photosynthesis with animal-like consumer activity within the one cell. This form of nutrition, - “mixotrophy”, supports the growth of organisms important for food chains and biogeochemical cycles removing atmospheric CO2; they are also causative agents of harmful algal blooms. In consequence of this revised paradigm, laboratory and field - research approaches, management policies and allied computer modelling tools, are arguably no longer fit for purpose. MixITiN brings together European world-class research and training centres from 9 different countries, with skillsets from molecular - biology, physiology and computer modelling, to marine and coastal zone management, public and media engagement. MixITiN will train ESRs in multinational and multidisciplinary centres of excellence, with intersectoral engagement enabling them to gain - employment in various sectors such as consultancy, government, academic, or allied industries. The synergy of training approaches provided to the ESRs will raise their capabilities and progress science beyond the current state-of-the-art to enable - improved management of marine resources. - - 2021-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - MixITiN - - - H2020-MSCA-ITN-2017 - - - 766327 - - - - - UNIVERSITY OF GLASGOW - - - EUR 195 454,80 - - - Perpendicular Magnetic Anisotropy: from Topological Defects to Reconfigurable Magnetic Devices - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The present project aims to explore and control the behavior of magnetic topological defects in weak Perpendicular Magnetic Anisotropy materials by creating different hard/soft magnetic nanostructures with reconfigurable - properties.Both, static and dynamic behaviors will be exploded and finally, a demonstration device will be prepared: a reconfigurable magnonic crystal with potential applications in information and communication technologies.Weak perpendicular - magnetic anisotropy materials present fascinating magnetic stripe domain arrangements sharing phenomenology with other self-organized systems.These magnetization configurations can be understood as a 2D magnetic crystal.Topological defects within the - stripes’ lattice condition and drive the magnetization processes of the system being their study a key factor for both, fundamental and technological goals. One of the objectives of the project is to go a step further in the study of magnetic - topological defects in these systems. We want to characterize, with unprecedented detail, the behavior of magnetization textures and control their evolution by locally tuning the film properties.Not only static properties will be analyzed, but also - the dynamics. It will allow to observe interesting spin wave phenomena, and ultimately, to identify and excite the dynamic modes of topological defects.To achieve this, a unique combination of ferromagnetic resonance with Lorentz Transmission - Electron Microscopy will be used, with guidance from micromagnetic simulations. - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - MAGTOPRECON - - - H2020-MSCA-IF-2016 - - - 746958 - - - - - UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6 - UPPSALA UNIVERSITET - INSTITUT MINES-TELECOM - KUNGLIGA TEKNISKA HOEGSKOLAN - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - INESC ID - INSTITUTO DE ENGENHARIADE SISTEMAS E COMPUTADORES, INVESTIGACAO E DESENVOLVIMENTO EM LISBOA - JACOBS UNIVERSITY BREMEN GGMBH - SOFTBANK ROBOTICS EUROPE - - - EUR 3 890 624,76 - - - Advancing intuitive human-machine interaction with human-like social capabilities for education in schools - - - EUR 3 890 624,76 - - - France - Sweden - France - Sweden - Switzerland - Portugal - Germany - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - ANIMATAS will establish a leading European Training Network (ETN) devoted to the development of a new generation of creative and critical research leaders and innovators who have a skill-set tailored for the creation of social - capabilities necessary for realising step changes in the development of intuitive human-machine interaction (HMI) in educational settings. This will be achieved through (1) a transnational network of universities and industrial partners that will - supervise and deliver specialized training for early stage researchers (ESRs), and (2) the cross-fertilization of state-of-the-art methods from the domains of social robotics, embodied virtual characters, social and educational sciences in order to - facilitate the development of skills necessary to design machines capable of engaging in intuitive sustained encounters with teachers and children. The ETN will ensure an integrative approach to the development of new capabilities with a view to - their impact on whole system performance in terms of the complete HMI loop. This will be done by building industry–guided showcases that integrate the social capabilities developed by the ESRs. The participation of industrial partners will support - the translation of new academic results to the market-place and a better transfer of knowledge between different sectors. The exposure of the non- academic sector to the ESRs has a great market potential that our industrial partners aim to capitalize - upon in terms of recruiting young talents after the end of the project and adopting ANIMATAS’ advances in intuitive HMI for future product lines. This will greatly benefit the ESRs, which will be provided with new career perspectives in the social - robotics and ed-tech industries. The ETN will strengthen Europe’s capacity in research and innovation by nurturing a new generation of highly skilled ESRs with an entrepreneurial mind-set and an understanding of intuitive HMI and potential products - in these emerging markets. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - France - - - ANIMATAS - - - H2020-MSCA-ITN-2017 - - - 765955 - - - - - UNIVERSITAET HAMBURG - UPPSALA UNIVERSITET - TECHNOLOGIKO PANEPISTIMIO KYPROU - UNIVERSITY OF GLASGOW - STIFTUNG PREUSSISCHER KULTURBESITZ - AARHUS UNIVERSITET - ASHOKA UK - - - EUR 3 406 970,52 - - - PARTICIPATORY MEMORY PRACTICES. Concepts, strategies, and media infrastructures for envisioning socially inclusive potential futures of European Societies through culture - - - EUR 3 406 970,52 - - - Germany - Sweden - Cyprus - United Kingdom - Germany - Denmark - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Other - - Diverging forces across European societies, most visible in both the contemporary nationalist movements and Islamist radicalization, demand a socially inclusive public memory. Its implementation calls for new strategies, - practices, and infrastructures for staging and empowering membership and contribution of people from diverse social and cultural backgrounds for past and future development in Europe. To reach this goal, research needs to develop a comprehensive - understanding on concepts, practices, and media infrastructures that facilitate the partaking of people from various backgrounds in the heritage building work of memory institutions (libraries, archives, and museums). The POEM-ETN will provide this - comprehensive knowledge by studying in practice theoretical approaches on how connectivities are built by 1) institutions, 2) people and groups, and 3) media infrastructures for a socially inclusive, participatory heritage work and what facilitates - or hinders collaboration. Therefore, a new generation of professionals will be trained through an innovative training programme and supervised by peer networks of transdisciplinary knowledge to act as change agents, brokers, and problem solvers in - this contested field of heritage work. The comprehensive transdisciplinary composition of the consortium involving universities, memory institutions, civil society organisations, and SMEs from public and private sectors will therefore provide the - POEM fellows with transdisciplinary knowledge on cultural and social analysis as well as on transferrable skills with respect to the changing socio-technical, organisational, legal, economic, and ethical issues to address future challenges for - participatory memory work. - - 2022-03-31, Grant Agreement signed - - - 2018-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - POEM - - - H2020-MSCA-ITN-2017 - - - 764859 - - - - - UNIVERSITEIT TWENTE - UNIVERSITEIT TWENTE - - - EUR 1 500 000 - - - Advancing cell based therapies by supporting implant survival - - - EUR 1 500 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Tissue engineering aims at the creation of living implants to replace, repair, or regenerate damaged, diseased, or aged tissues, which holds tremendous possibilities to both extend our lives and improve our quality of life. - During the last decades, our ability to create small tissues to heal small animals e.g. mice and rats has taken a breath taking leap. However, we have relentlessly struggled to create viable tissues of human-relevant sizes. Creating solid large - tissues imposes lethal nutrient diffusion limitations, which causes the living implant to suffer from starvation, loss of function, and inevitable failure. - - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - ENABLE - - - ERC-2017-STG - - - 759425 - - - - - UNIVERSITAT WIEN - - - EUR 178 156,80 - - - Mass-waste modelling across scales - - - EUR 178 156,80 - - - Austria - - - Higher or Secondary Education Establishments - - "Mass-waste events not only cause geomorphological changes on our planet but they are often natural hazards, causing significant economic impact or seriously endangering human lives. Sufficiently understanding and predicting - them is an important task both for the scientific community as well as to the decision-making bodies and community leaders all around the world. The importance of the topic is also emphasized in the EU Horizon 2020 third pillar ""Societal - Challenges"". - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Austria - - - MAWAMOSCA - - - H2020-MSCA-IF-2016 - - - 743713 - - - - - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - - - EUR 1 499 390 - - - Computational Molecular Materials Discovery - - - EUR 1 499 390 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The objective of the project is to develop a computational approach to accelerate the discovery of molecular materials. These materials will include porous molecules, small organic molecules and macromolecular polymers, which - have application as a result of either their porosity or optoelectronic properties. The applications that will be targeted include in molecular separations, sensing, (photo)catalysis and photovoltaics. To achieve my aims, I will screen libraries of - building blocks through a combination of techniques including evolutionary algorithms and machine learning. Through the application of cheminformatics algorithms, I will target the most promising libraries, assess synthetic diversity and - accessibility and analyse structure-property relationships. I will develop software that will predict the (macro)molecular structures and properties; the molecular property screening calculations will include void characterisation, binding energies, - diffusion barriers, local assembly, charge transport and energy level assessment. A consideration of synthetic accessibility at every stage will be central to my approach, which will ensure the realisation of our predicted targets. I have several - synthetic collaborators who can provide pathways to synthetic realisation. Improved materials in this field have the potential to either reduce our energy needs or provide renewable energy, helping the EU meet the targets of the 2030 Energy Strategy. - - 2023-03-31, Grant Agreement signed - - - 2018-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - CoMMaD - - - ERC-2017-STG - - - 758370 - - - - - KOC UNIVERSITY - KOC UNIVERSITY - - - EUR 1 500 000 - - - Computational Simulations of MOFs for Gas Separations - - - EUR 1 500 000 - - - Turkey - Turkey - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Metal organic frameworks (MOFs) are recently considered as new fascinating nanoporous materials. MOFs have very large surface areas, high porosities, various pore sizes/shapes, chemical functionalities and good - thermal/chemical stabilities. These properties make MOFs highly promising for gas separation applications. Thousands of MOFs have been synthesized in the last decade. The large number of available MOFs creates excellent opportunities to develop - energy-efficient gas separation technologies. On the other hand, it is very challenging to identify the best materials for each gas separation of interest. Considering the continuous rapid increase in the number of synthesized materials, it is - practically not possible to test each MOF using purely experimental manners. Highly accurate computational methods are required to identify the most promising MOFs to direct experimental efforts, time and resources to those materials. In this - project, I will build a complete MOF library and use molecular simulations to assess adsorption and diffusion properties of gas mixtures in MOFs. Results of simulations will be used to predict adsorbent and membrane properties of MOFs for - scientifically and technologically important gas separation processes such as CO2/CH4 (natural gas purification), CO2/N2 (flue gas separation), CO2/H2, CH4/H2 and N2/H2 (hydrogen recovery). I will obtain the fundamental, atomic-level insights into - the common features of the top-performing MOFs and establish structure-performance relations. These relations will be used as guidelines to computationally design new MOFs with outstanding separation performances for CO2 capture and H2 recovery. - These new MOFs will be finally synthesized in the lab scale and tested as adsorbents and membranes under practical operating conditions for each gas separation of interest. Combining a multi-stage computational approach with experiments, this project - will lead to novel, efficient gas separation technologies based on MOFs. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Turkey - - - COSMOS - - - ERC-2017-STG - - - 756489 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 158 121,60 - - - Using global marine metagenomics to understand MERcury microbial associated processes: finding a CURE for mercury contaminated environments - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - Millions of people are exposed to harmful levels of the potent neurotoxin mercury (Hg), concretely to the organic form methylmercury (MeHg) that bio-accumulates in organisms and biomagnifies in marine food webs. Understanding - Hg transformations in the ocean is critical because commercial fish are mainly marine species. While it is well known that both MeHg formation and degradation are genetically mediated by prokaryotes, there are still sizable gaps in the fundamental - understanding of the organisms and mechanisms involved in Hg transformations in the environment and therefore a clear lack of available techniques for Hg removal based on the action of these genes. MER-CURE aims at filling this gap by providing the - first Hg reference gene catalogue at a global ocean scale and by quantifying the individual and/or combined effect of the activity of these genes in a pilot Hg removal system. MER-CURE develops a novel and multidisciplinary methodological approach by - merging omics and Hg stable isotope tracer technologies for studying the biogeochemistry and detoxification of Hg. Concretely, the fellow will take advantage of the available sequenced metagenomes and metatranscriptomes and isolates from the Global - Ocean Circunnavigation Expedition Malaspina. She will carry out laboratory conducted experiments to elucidate the capacity of different marine isolates to detoxify Hg-contaminated sediments. MER-CURE will contribute to advance knowledge by - identifying “where” and “which” prokaryotes in the ocean are involved in Hg cycling and to produce readily applicable results that can in the future help municipality and private industries. MER-CURE is committed to knowledge sharing and to engage - the public into the action. The incorporation of metagenomic and metatranscriptomics analyses in Dr. Bravo toolbox will lead the fellow to master a rather unique combination of chemistry, biology, experimental approaches, public engagement, and - knowledge sharing and communication skills. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - MER-CURE - - - H2020-MSCA-IF-2016 - - - 749645 - - - - - UNIVERZITA KARLOVA - UNIVERZITA KARLOVA - - - EUR 924 375 - - - Accuracy and precision for molecular solids - - - EUR 924 375 - - - Czech Republic - Czech Republic - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The description of high pressure phases or polymorphism of molecular solids represents a significant scientific challenge both for experiment and theory. Theoretical methods that are currently used struggle to describe the - tiny energy differences between different phases. It is the aim of this project to develop a scheme that would allow accurate and reliable predictions of the binding energies of molecular solids and of the energy differences between different phases. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Czech Republic - - - APES - - - ERC-2017-STG - - - 759721 - - - - - THE UNIVERSITY OF BIRMINGHAM - - - EUR 183 454,80 - - - van der Waals Heterostructures for Innovative PhotoCATalysts - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Engineering of atomic (two-dimensional (2D)) layered solids is receiving immense attention from the scientific community due to the possibilities of tuning the optical, mechanical, electronic and electrochemical properties by - combinatorial stacking of different atomic layers as novel candidates for energy and environmental applications. Van der Waals solids (vdW) of Semiconducting Transition Metal Dichalcogenides (STMD) have been largely investigating 2D materials, where - its physico-chemical properties show a drastic contrast in comparison to its bulk. Visible light absorption, indirect to direct bandgap transition, layer dependent photoluminescence (PL) etc. are some of the stark contrasts in atomically layered STMD - vdW crystals from bulk, making them unique for photocatalysis and photo-(electro) catalysis (PEC) applications. In this work, Fabrication of variety of novel heterogeneous STMD clusters with combinations of different transition metal (TM): Mo, W and - V and chalcogenide (C): S, Se and Te by cluster beam deposition will be carried out for the efficient visible light photocatalysis and PEC applications. Size and edge termination dependent photophysical properties will be investigated and further - implemented for the efficient visible light PEC from this kind of vdW solids. A dual-target, magnetron-sputtering gas condensation cluster source will be used to deposit pristine combinatorial stacked nanoclusters of TMs and Cs onto various - substrates. The photocatatlytic reaction kinetics will be estimated from the visible light absorption, Raman/PL spectroscopy and photoconductivity studies. Further PEC activity towards HER/oxygen reduction reaction (ORR)/oxygen evolution reaction - (OER) from the STMD vdW nanoclusters will be evaluated from linear sweep voltammetry and cyclic voltammetry in acidic and basic electrolytes in dark and light conditions. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - WHIPCAT - - - H2020-MSCA-IF-2016 - - - 750929 - - - - - TECHNISCHE UNIVERSITAET MUENCHEN - TECHNISCHE UNIVERSITAET MUENCHEN - - - EUR 150 000 - - - Modular Platform for Controlled Ion Beam Generation - - - EUR 150 000 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Countless sophisticated macroscopic products rely on innovative materials with unique features, designed with nanoscale precision. To harness the variety of functionalities provided by biomolecules and other complex molecular - species as the key ingredient for the design of prospective advanced nanosystems and materials, a current technological gap must be closed: the lack of a universal method capable to handle fragile molecules under vacuum conditions without - compromising their integrity. With the present project we aim to introduce a versatile and powerful platform based on innovative methodological advances to overcome this obstacle. The envisioned technology is designated CIB (controlled ion beam) and - will allow the generation of ultrapure ion beams from any solvable substance in a fully controlled manner using a cost-effective, marketable setup. The novel instrumentation capitalizes on achievements within the ERC project 'MolArt' and will be - suitable for highly sophisticated deposition processes for nanofabrication and nanotechnology, while furnishing at the same time a general module integrable in analytical mass spectrometry (MS/ Proteomics). SoftBeam, the prototype instrument to be - accomplished within this PoC project is our pilot application where CIB is firstly realized and validated. With this technology an entire new class of sensitive substances can be routinely processed in a size-selective manner. Boosted flux - intensities reduce processing time and fully controllable energy of the molecules results in a highly increased reproducibility, cleanliness and homogeneity of molecular beams generated. The modular platform is adaptable to various disciplines and - has the potential to become a standard tool in the nanotechnology and analytical (bio)chemistry community. - - 2019-06-30, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Germany - - - SoftBeam - - - ERC-2017-PoC - - - 780907 - - - - - HELMHOLTZ ZENTRUM FUR OZEANFORSCHUNG KIEL - HELMHOLTZ ZENTRUM FUR OZEANFORSCHUNG KIEL - - - EUR 1 499 989 - - - Male pregnancy – Unravelling the coevolution of parental investment and immune defence - - - EUR 1 499 989 - - - Germany - Germany - - - Research Organisations - Research Organisations - - The question of how sex roles and parental investment have evolved belongs to the most controversial unresolved issues in evolutionary biology. The costliest form of reproduction regarding parental investment is viviparity. - Its independent evolution in most vertebrate groups has required drastic morphological and genomic reorganisations in the sex bearing the young. Yet our knowledge is heavily biased towards mammals, where changes in the immune system and microbial - composition are associated with pregnancy and placentation. Which factors have caused the selection and accompanied evolution of viviparity in other vertebrates remains severely understudied. - - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - MALEPREG - - - ERC-2017-STG - - - 755659 - - - - - TECHNISCHE UNIVERSITAET WIEN - TECHNISCHE UNIVERSITAET WIEN - - - EUR 1 997 202,49 - - - Tuneable Catalyst Surfaces for Heterogeneous Catalysis – Electrochemical Switching of Selectivity and Activity - - - EUR 1 997 202,49 - - - Austria - Austria - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In heterogeneous catalysis surfaces decorated with uniformly dispersed, catalytically highly active particles are a key requirement for excellent performance. One of the main tasks in catalysis research is the continuous - improvement or development of catalytically active materials. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Austria - - - TUCAS - - - ERC-2017-STG - - - 755744 - - - - - UPPSALA UNIVERSITET - UPPSALA UNIVERSITET - - - EUR 1 467 500 - - - Jigsaw puzzles at atomic resolution: Computational design of GPCR drugs from fragments - - - EUR 1 467 500 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Despite technological advances, industry struggles to develop new pharmaceuticals and therefore novel strategies for drug discovery are urgently needed. G protein-coupled receptors (GPCRs) play important roles in numerous - physiological processes and are important drug targets for neurological diseases. My research focuses on modelling of GPCR-ligand interactions at the atomic level, with the goal to increase knowledge of receptor function and develop new methods for - drug discovery. Breakthroughs in GPCR structural biology and access to sensitive screening assays provide opportunities to utilize fragment-based lead discovery (FBLD), a powerful approach for drug design. The objective of the project is to create a - computational platform for FBLD, with a vision to transform the early drug discovery process for GPCRs. As structural information for these targets is limited, predictive models of receptor-fragment complexes will be crucial for the successful use of - FBLD. In this project, computational structure-based methods for discovery of fragment ligands and further optimization of these to potent leads will be developed. These techniques will be applied to address two difficult problems in drug discovery. - The first of these is to design ligands of peptide-binding GPCRs that have been challenging for existing methods. One of the promises of FBLD is to provide access to difficult targets, which will be explored by combining molecular docking and - biophysical screening against peptide-GPCRs to identify novel lead candidates. A second challenge is that efficient treatment of neurological disorders often requires modulation of multiple targets, which also will be the focus of the project. - - 2022-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Sweden - - - FRAGMENT2DRUG - - - ERC-2016-STG - - - 715052 - - - - - STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS - STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS - - - EUR 1 950 775 - - - Single-molecule visualization of transcription dynamics to understand regulatory mechanisms of transcriptional bursting and its effects on cellular fitness - - - EUR 1 950 775 - - - Netherlands - Netherlands - - - Research Organisations - Research Organisations - - Transcription in single cells is a stochastic process that arises from the random collision of molecules, resulting in heterogeneity in gene expression in cell populations. This heterogeneity in gene expression influences cell - fate decisions and disease progression. Interestingly, gene expression variability is not the same for every gene: noise can vary by several orders of magnitude across transcriptomes. The reason for this transcript-specific behavior is that genes are - not transcribed in a continuous fashion, but can show transcriptional bursting, with periods of gene activity followed by periods of inactivity. The noisiness of a gene can be tuned by changing the duration and the rate of switching between periods - of activity and inactivity. Even though transcriptional bursting is conserved from bacteria to yeast to human cells, the origin and regulators of bursting remain largely unknown. Here, I will use cutting-edge single-molecule RNA imaging techniques to - directly observe and measure transcriptional bursting in living yeast cells. First, bursting properties will be quantified at different endogenous and mutated genes to evaluate the contribution of cis-regulatory promoter elements on bursting. Second, - the role of trans-regulatory complexes will be characterized by dynamic depletion or gene-specific targeting of transcription regulatory proteins and observing changes in RNA synthesis in real-time. Third, I will develop a new technology to visualize - the binding dynamics of single transcription factor molecules at the transcription site, so that the stability of upstream regulatory factors and the RNA output can directly be compared in the same cell. Finally, I will examine the phenotypic effect - of different bursting patterns on organismal fitness. Overall, these approaches will reveal how bursting is regulated at the molecular level and how different bursting patterns affect the heterogeneity and fitness of the organism. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - BURSTREG - - - ERC-2017-STG - - - 755695 - - - - - Eidgenössische Technische Hochschule Zürich - CENTRO EUROPEO DI FORMAZIONE E RICERCA IN INGEGNERIA SISMICA - JRC -JOINT RESEARCH CENTRE- EUROPEAN COMMISSION - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - LABORATORIO NACIONAL DE ENGENHARIA CIVIL - PANEPISTIMIO PATRON - UNIVERSITY OF BRISTOL - PUBLIC SCIENTIFIC INSTITUTE-INSTITUTE OF EARTHQUAKE ENGINEERING AND ENGINEERING SEISMOLOGY SS CYRIL AND METHODIUS UNIVERSITY SKOPJE IZIIS - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - UNIVERSITA DEGLI STUDI DI TRENTO - UNIVERSIDADE DO PORTO - UNIVERSIDAD POLITECNICA DE MADRID - BOGAZICI UNIVERSITESI - ARISTOTELIO PANEPISTIMIO THESSALONIKIS - HELMHOLTZ ZENTRUM POTSDAM DEUTSCHESGEOFORSCHUNGSZENTRUM GFZ - KONINKLIJK NEDERLANDS METEOROLOGISCH INSTITUUT-KNMI - INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA PAMANTULUI - NATIONAL OBSERVATORY OF ATHENS - UPPSALA UNIVERSITET - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - NATURAL ENVIRONMENT RESEARCH COUNCIL - Euro-Mediterranean Seismological Centre - UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II. - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - AMRA - ANALISI E MONITORAGGIO DEL RISCHIO AMBIENTALE SCARL - STIFTELSEN NORSAR - Instytut Geofizyki Polskiej Akademii Nauk - ISTITUTO NAZIONALE DI GEOFISICA E VULCANOLOGIA - INSTITUTO SUPERIOR TECNICO - BUREAU DE RECHERCHES GEOLOGIQUES ET MINIERES - UNIVERSITETET I BERGEN - - - EUR 10 000 000 - - - Seismology and Earthquake Engineering Research Infrastructure Alliance for Europe - - - EUR 11 090 779,02 - - - Switzerland - Italy - Belgium - France - Portugal - Greece - United Kingdom - Former Yugoslav Republic of Macedonia - United Kingdom - Italy - Portugal - Spain - Turkey - Greece - Germany - Netherlands - Romania - Greece - Sweden - Spain - United Kingdom - France - Italy - France - Italy - Norway - Poland - Italy - Portugal - France - Norway - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Other - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - - SERA is the "Seismology and Earthquake Engineering Research Infrastructure Alliance for Europe", responding to the priorities identified in the call INFRAIA-01-2016-2017 Research Infrastructure for Earthquake Hazard. - - 2020-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.2."> - - - INFRAIA-01-2016-2017 - Integrating Activities for Advanced Communities - - - RIA - Research and Innovation action - - - Switzerland - - - SERA - - - H2020-INFRAIA-2016-1 - - - 730900 - - - - - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - CIIMAR - Centro Interdisciplinar de Investigação Marinha e Ambiental - EUROPEAN MOLECULAR BIOLOGY LABORATORY - UNIVERSITE LIBRE DE BRUXELLES - UNIVERSITETET I BERGEN - NATIONAL UNIVERSITY OF IRELAND GALWAY - UNIVERSITY OF BRISTOL - HITS GGMBH - GENERALDIREKTION DER STAATLICHE NATURWISSENSCHAFTLICHEN SAMMLUNGEN BAYERNS - INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE - UNIVERSITY COLLEGE LONDON - FACULTY OF SCIENCE UNIVERSITY OF ZAGREB - Era7 Information Technologies SL - PENSOFT PUBLISHERS - - - EUR 3 810 685,32 - - - Comparative genomics of non-model invertebrates - - - EUR 3 810 685,32 - - - Germany - Portugal - Germany - Belgium - Norway - Ireland - United Kingdom - Germany - Germany - France - United Kingdom - Croatia - Spain - Bulgaria - - - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Invertebrates, i.e., animals without a backbone, represent 95% of animal diversity on earth but are a surprisingly underexplored reservoir of genetic resources. The content and architecture of their genomes remain poorly known - or understood, but such knowledge is needed to fully appreciate their evolutionary, ecological and socio--economic importance, as well as to leverage the benefits they can provide to human well-being, for example as a source for novel drugs and - biomimetic materials. Europe is home to significant world-leading expertise in invertebrate genomics but research and training efforts are as yet uncoordinated. IGNITE will bundle this European excellence to train a new generation of scientists - skilled in all aspects of invertebrate genomics. We will considerably enhance animal genome knowledge by generating and analysing novel data from undersampled invertebrate lineages and developing innovative new tools for high-quality genome assembly - and analysis. Well-trained genomicists are in increasing demand in universities, research institutions, as well as in software, biomedical, and pharmaceutical companies. Through their excellent interdisciplinary and intersectoral training spanning - from biology and geobiology to bioinformatics and computer science, our graduates will be in a prime position to take up leadership roles in both academia and industry in order to drive the complex changes needed to advance sustainability of our - knowledge-based society and economy. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - IGNITE - - - H2020-MSCA-ITN-2017 - - - 764840 - - - - - UNIVERSITAET BREMEN - UNIVERSITAET BREMEN - - - EUR 1 486 250 - - - The Legacy of Colonialism: Origins and Outcomes of Social Protection - - - EUR 1 486 250 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Social protection has been one of the most popular instruments for promoting human development across the globe. However, the great majority of the global population is not or only partly covered by social protection. - Especially in developing countries it is often the very poorest who do not receive essential social benefits. This is highly problematic since inclusive social protection is assumed to be a key factor for national productivity, global economic growth - and domestic stability. Social protection in many developing countries can be traced back to colonial times. Surprisingly, the influence of colonialism has been a blind spot for existing theories and empirical studies of comparative social policy. In - this project it is argued that the colonial legacy in terms of the imperial strategy of the colonial power, the characteristics of the colonized society and the interplay between the two is crucial in explaining early and contemporary social - protection. Hence, the main objective of this project is to systematically understand how colonialism has shaped the remarkable differences in social protection and its postcolonial outcomes. Given the paucity of our information and understanding of - social protection in former colonies, an interactive dataset on the characteristics, origins and outcomes of social protection will be developed including comprehensive data on former British and French colonies from the beginning of the 20th century - until today. The dataset will be backed by insights derived from four case studies elucidating the causal mechanisms between the colonial legacy and early and contemporary social protection. The proposed project breaks new ground by improving our - understanding of why social protection in some developing countries has led to more inclusive societies while reinforcing existing inequalities in others. Such an understanding is a prerequisite in informing the contemporary struggle against poverty - and social inequality. - - 2023-03-31, Grant Agreement signed - - - 2018-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - COLSOC - - - ERC-2017-STG - - - 755129 - - - - - SCUOLA NORMALE SUPERIORE - - - EUR 180 277,20 - - - Civil society organizations and the politics of long-term care reform: coalitions and multiple inequalities - - - EUR 180 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - Population ageing and gender inequality are cross-cutting political and societal challenges facing Europe. AGenDA meets this challenges by implementing novel and interdisciplinary state-of the-art research on the interaction - between multiple intersecting inequalities in Long-Term Care (LTC) reforms. It focuses on the impact of civil society organizations (CSOs) mobilizing around gender, age and disability in reform coalitions in Italy and Spain. Through research and - public engagement, AGenDA’s strives to promote inclusive equality in LTC systems, thereby contributing to meet Horizon 2020 challenges “Health, demographic change and wellbeing” and “Inclusive, Innovative and Reflective societies”. By engaging civil - society, it promotes participation and effectiveness of social actors in decision-making processes as highlighted in Europe 2020 strategy. By focusing on countries which are laggards in the development of LTC and gender equality policies, AGenDA - produces and disseminates knowledge on the social and political obstacles that impede the development of fair and inclusive LTC systems, thereby strengthening integration and cohesion within the European Union. In line with MSCA objectives, AGenDA - includes a comprehensive training plan to enhance the future career opportunities and inter-sectoral employability of the researcher. These objectives will be achieved through excellent training-through-research, an academic secondment developing new - interdisciplinary and methodological competencies and a non-academic secondment providing access to policy networks and on-the-job-training in outreach and public engagement. The ambitious dissemination and communication plan aims at enhancing the - international visibility of the project, promoting knowledge-transfer between all actors involved, and producing wider impact on EU institutions, policy-makers, CSOs, academics and the general public. - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - AGenDA - - - H2020-MSCA-IF-2016 - - - 746168 - - - - - UNIVERSITAT DES SAARLANDES - UNIVERSITAT DES SAARLANDES - - - EUR 2 460 000 - - - Inpainting-based Compression of Visual Data - - - EUR 2 460 000 - - - Germany - Germany - - - Peter Druschel - Tel.: +4968193039100 - Fax: +4968193036029 - Higher or Secondary Education Establishments - Corinna Hahn - Tel.: +49 681 95 92 3362 - Fax: +49 681 95 92 3370 - Higher or Secondary Education Establishments - Corinna Hahn - Tel.: +49 681 95 92 3362 - Fax: +49 681 95 92 3370 - - Generating huge amounts of visual data, be it images or videos, has never been easier than today. This creates a growing demand for lossy codecs (coders and decoders) that produce visually convincing results also for very high - compression rates. Popular transform-based codecs such as JPEG and JPEG 2000 have reached a state where one cannot expect significant improvements anymore. To go beyond their limitations, fundamentally different ideas are needed. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - INCOVID - - - ERC-2016-ADG - - - 741215 - - - - - CONSIGLIO NAZIONALE DELLE RICERCHE - CONSIGLIO NAZIONALE DELLE RICERCHE - DHITECH DISTRETTO TECNOLOGICO HIGH-TECH SCARL - - - EUR 149 406 - - - Electro-optical polariton router - - - EUR 149 406 - - - Italy - Italy - Italy - - - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - In this proposal we plan to bring to a development stage TRL 3 an electro-optical device working at room temperature and based on polaritons (an hybrid photon-exciton particle) made of 2D perovskites and of an optical surface - mode in a Distributed Bragg Reflector waveguide. Such a device could lead to extremely compact and ultrafast electro-optical modulators that can be fully integrated in a microchip to allow for fast signal communications between each peripheral - component of a processor. As a matter of fact one of the major bottlenecks in processing speed is caused by retardations and dissipations in the interconnections between the CPU and the memory elements as well as other interconnect functions. - Conversion of the electrical signal into an optical one can allow for faster and more efficient processing. Our prototype can allow for switching and routing of guided optical beams via electrical signals using the intrinsic nonlinearities of the - hybrid photon-exciton states. - - 2019-03-31, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Italy - - - ElecOpteR - - - ERC-2017-PoC - - - 780757 - - - - - UNIVERSITY COLLEGE LONDON - UNIVERSITY COLLEGE LONDON - PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE - - - EUR 2 499 908 - - - Smartphones, Smart Ageing and mHealth - - - EUR 2 549 908 - - - United Kingdom - United Kingdom - Chile - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project will investigate fundamental changes in people’s relationship to age and health associated with the global rise of the smartphone. The aim is to combine an intellectual challenge in understanding the contemporary - nature of age and the impact of new media, with an applied challenge to use this knowledge to help make mHealth a more effective intervention. - - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - SmartPhoneSmartAging - - - ERC-2016-ADG - - - 740472 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 149 997 - - - Functional magnetic materials for biomedical applications - - - EUR 149 997 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - A range of new medical therapies and diagnostics based on magnetic nanomaterials have recently been proposed. These include cancer therapies, stem cell therapies, microfluidic diagnostic devices and immunoassays. However, very - few biotechnology magnetic nanomaterials are currently available commercially; most investigators fabricate their own. This is a serious limitation to the development of this emerging area within nanomedicine. This proposal aims to transfer a number - of magnetic nanomaterials from the University physics laboratory where they were developed as part of an ERC AdG grant into an existing small company where they can then be made available to researchers across the world on a commercial basis. - - 2019-05-31, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - BioMagMat - - - ERC-2017-PoC - - - 779822 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 500 000 - - - Waves of history in the South Pacific: A gene-culture coevolutionary approach - - - EUR 1 500 000 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Modern humans have colonized every possible ecological niche, with the latest expansions being those into the remote islands of the South Pacific. This success has been underpinned both by genetic adaptations to new ecological - conditions and by an ever-accumulating store of technological and cultural knowledge gained through social learning. Our dual inheritance systems of genetics and culture interact in unique and unexpected ways, making human history vastly more - difficult to infer than for any other species. The emerging field of gene-culture coevolution promises to provide a cohesive framework for modeling the interplay of genes and culture, and will revolutionize our understanding of human historical - processes. The Waves project will build the tools necessary to establish gene-culture coevolution in the genomic-era, extending cutting-edge population genetic techniques – including spatial simulation – and allowing the natural integration of data - from across genomics, archaeogenetics, archaeology and historical linguistics. We will focus on the South Pacific, a region whose past demography remains largely unresolved. While the population history of this region is relatively short it appears - extremely complex, comprising not only multiple waves of colonization but also the existence of wide and ongoing interaction spheres through which both seafaring peoples and their cultures maintained long-distance connections. By generating - comprehensive new ancient and present-day genome-wide datasets across Near and Remote Oceania – and analyzing them alongside historical linguistic and cultural data – the Waves project will create the first unified gene-culture coevolutionary history - of the South Pacific. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - Waves - - - ERC-2017-STG - - - 758967 - - - - - TEL AVIV UNIVERSITY - TEL AVIV UNIVERSITY - - - EUR 1 500 000 - - - Robustness and specialization among hormone transporters: Redundant and unique roles - - - EUR 1 500 000 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - "Plant growth and development is governed by finely tuned, highly regulated hormone gradients. Impressive progress has been made in understanding plant hormone signaling, but knowledge on the mechanisms underlying their - precise localization at the tissue and subcellular levels is still very limited. We and others have recently identified the first bona fide GA transporters in plants as members of the NPF protein family. Proteins from the ABC family were shown to - transport the CK, ABA, and auxin hormones. Although these studies suggested specialized functions for members of these large protein families, progress in understanding their level of specialization has been limited by the scarcity of - loss-of-function phenotypes, masked by the highly redundant plant genome. The goal of this proposal is to reveal the robust and specialized function of the NPF and ABC plant hormone transporter families. The project places key technological - challenges that require multi-disciplinary expertise to examine how plants balance redundancy and specialization to tightly regulate hormone localization. Broad and targeted transportome screens using multi-targeted artificial miRNAs and CRISPR - technology in Arabidopsis and tomato, respectively, are designed to unveil novel plant hormone transporters, with an emphasis on subcellular localized transporters and the missing GA exporters. Specialization and robustness of candidate transporters - will be evaluated by integrating in vitro transport assays with in vivo growth and development experiments. I believe that the proposed ""redundant-free"" populations will lead to new paradigms in plant genetics and would explain how gene families - have developed robustness together with unique and diverse specialization. Importantly, our combined genetic and organelle-specific hormone profiling approaches will establish fundamental new concepts regarding plant hormone localization, activity, - and specificity at the subcellular level." - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Israel - - - RobustHormoneTrans - - - ERC-2017-STG - - - 757683 - - - - - UNIVERSITEIT GENT - UNIVERSITEIT GENT - - - EUR 1 391 250 - - - Chip Scale Electrically Powered Optical Frequency Combs - - - EUR 1 391 250 - - - Belgium - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In ELECTRIC, I will integrate electrically powered optical frequency combs on mass manufacturable silicon chips. This will allow for making use of all the advantageous properties of these light sources in real-life situations. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Belgium - - - ELECTRIC - - - ERC-2017-STG - - - 759483 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 142 324 - - - Device for much improved performance portable power - - - EUR 142 324 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - "Portable power (~1-20 W) for small electronic devices is a high value added market. Batteries are the most convenient power devices but have relatively low energy capacity per unit mass and also slow recharge times. - Micro-solid oxide fuel (micro-SOFC) cells are much better on both counts but currently operate at too high of a temperature (>500°C). This project will reduce that temperature by 200°C in prototype test devices. It will do this by exploiting much - improved materials in the micro-SOFC, these materials having been discovered and developed in an ERC AdG grant held by the PI. The project will involve prototype device fabrication and testing in conjunction with a small start-up company, the - ultimate aim being to take the technology forward to market." - - 2019-11-30, Grant Agreement signed - - - 2018-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - Portapower - - - ERC-2017-PoC - - - 779444 - - - - - ALFRED-WEGENER-INSTITUT HELMHOLTZ-ZENTRUM FUR POLAR- UND MEERESFORSCHUNG - ALFRED-WEGENER-INSTITUT HELMHOLTZ-ZENTRUM FUR POLAR- UND MEERESFORSCHUNG - - - EUR 1 499 082 - - - Space-time structure of climate change - - - EUR 1 499 082 - - - Germany - Germany - - - Research Organisations - Research Organisations - - I will determine and use the space-time structure of climate change from years to millennia to test climate models, fundamentally improve the understanding of climate variability and provide a stronger basis for the - quantitative use of paleoclimate records. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - SPACE - - - ERC-2016-STG - - - 716092 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UPPSALA UNIVERSITET - - - EUR 1 753 287,89 - - - Firms and Their Networks - - - EUR 1 753 287,89 - - - France - France - Sweden - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - - There is mounting evidence that firms are becoming more fragmented; production is less often made “in-house”. Firms buy inputs from abroad. Tasks are often split in parts. Some are offshored, others are subcontracted. Hence, - firms buy services from other, local or international, firms. But they also supply inputs to other firms. Technical change, the internet, and globalization, all facilitate this transformation. - - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - France - - - FIRMNET - - - ERC-2016-ADG - - - 741467 - - - - - AARHUS UNIVERSITET - AARHUS UNIVERSITET - - - EUR 1 499 848 - - - Cholesterol and Sugar Uptake Mechanisms - - - EUR 1 499 848 - - - Denmark - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Cardiovascular disease, diabetes and cancer have a dramatic impact on modern society, and in great part are related to uptake of cholesterol and sugar. We still know surprisingly little about the molecular details of the - processes that goes on in this essential part of human basic metabolism. This application addresses cholesterol and sugar transport and aim to elucidate the molecular mechanism of cholesterol and sugar uptake in humans. It moves the frontiers of the - field by shifting the focus to in vitro work allowing hitherto untried structural and biochemical experiments to be performed. - - 2020-06-30, ongoing project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Denmark - - - CSUMECH - - - ERC-2014-STG - - - 637372 - - - - - RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - UNIVERSITY OF SOUTHAMPTON - UNIVERSITE JEAN MONNET SAINT-ETIENNE - ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON - OPEN DATA INSTITUTE LBG - - - EUR 3 885 922,44 - - - Answering Questions using Web Data - - - EUR 3 885 922,44 - - - Germany - Germany - United Kingdom - France - Greece - United Kingdom - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - - The H2020 work programme aims at increasing citizens’ participation in the digital society and making infrastructures “smart”. These processes are increasingly data-driven. Our central motivation is that sharing, connecting, - managing, analysing and understanding data on the Web will enable better services for citizens, communities and industry. However, turning web data into successful services for the public and private sector requires skilled web and data scientists, - and it still requires further research. WDAqua aims at advancing the state of the art by intertwining training, research and innovation efforts, centered around one service: data-driven question answering. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - WDAqua - - - H2020-MSCA-ITN-2014 - - - 642795 - - - - - TEL AVIV UNIVERSITY - TEL AVIV UNIVERSITY - - - EUR 1 496 875 - - - Engineering T cells and B cells for Immunotherapy using V(D)J recombination - - - EUR 1 496 875 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - T cell engineering has shown clinical success mainly in haematological cancers, but scaling up is challenging due to reliance on ex vivo manipulations. In addition, B cell engineering has not shown therapeutic efficacy to - date. Here, we propose a novel immunotherapy approach, allowing safe and efficient engineering of B cells and T cells, both ex vivo and in vivo. We will use adeno associated vectors (AAV) to integrate chimeric antigen receptor (CAR) or T cell - receptor (TCR) genes into loci coding TCR chains and to integrate antibody (Ab) genes into loci coding Ab chains. Previously, we used AAV facilitated gene targeting in vivo to ameliorate genetic diseases in mice. For lymphocytes we develop “VDJ - targeting”: A promoterless receptor/Ab gene flanked by recognition signal sequences (RSS) will be inserted into the endogenous locus by the recombination activating gene (RAG) complex during V(D)J recombination. Only developing lymphocytes, - expressing RAG, will incorporate the receptor/Ab gene, which will thus be expressed in potent naïve cells from the strong endogenous promoter. Targeted developing cells are subjected to negative selection, thus reducing risk of adverse autoimmunity. - Lack of promoter reduces spurious expression and oncogenic risk upon rare off-target integration. Targeting endogenous loci may allow allelic exclusion. In B cells it may allow utilizing the endogenous constant region to express a B cell receptor - and, upon activation, a secreted Ab. Activation may be accompanied by proliferation and affinity maturation, including somatic hypermutation and class switching, to allow a potent immune response, memory retention and diminished antigenic escape. - Where controlled autoimmunity is desired, we will engineer B cells to inducibly secret an auto-Ab. We will demonstrate efficacy in cancer and autoimmune disease models implanted with lymphocytes that we engineered while ex vivo differentiated and in - mice injected with vectors for in vivo VDJ targeting. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Israel - - - VDJtargeting - - - ERC-2017-STG - - - 759296 - - - - - KOBENHAVNS UNIVERSITET - KOBENHAVNS UNIVERSITET - - - EUR 1 497 260 - - - Signals from the Surface Snow: Post-Depositional Processes Controlling the Ice Core IsotopicFingerprint - - - EUR 1 497 260 - - - Denmark - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - For the past 50 years, our use of ice core records as climate archives has relied on the fundamental assumption that the isotopic composition of precipitation deposited on the ice sheet surface determines the ice core water - isotopic composition. Since the isotopic composition in precipitation is assumed to be governed by the state of the climate this has made ice core isotope records one of the most important proxies for reconstructing the past climate. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Denmark - - - SNOWISO - - - ERC-2017-STG - - - 759526 - - - - - DANMARKS TEKNISKE UNIVERSITET - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - UNIVERSITY COLLEGE LONDON - MEDIZINISCHE UNIVERSITAET WIEN - ICOMETRIX NV - PHILIPS MEDICAL SYSTEMS NEDERLAND BV - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - REGION HOVEDSTADEN - TECHNISCHE UNIVERSITAET MUENCHEN - TECHNISCHE UNIVERSITEIT EINDHOVEN - - - EUR 3 938 655,60 - - - Translational Brain Imaging Training Network - - - EUR 3 938 655,60 - - - Denmark - Switzerland - United Kingdom - Austria - Belgium - Netherlands - Germany - Denmark - Germany - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - "Brain diseases account for one third of the overall disease burden in Europe, and their already significant cost to society is expected to further escalate as a result of the aging European population. In recent decades, - medical imaging techniques such as computed tomography, ultrasound, and especially magnetic resonance imaging have gained a central role in the clinical management of disorders of the brain. A fundamental bottleneck in translating the wealth of - information contained in medical images into optimized patient care is the lack of computational tools to reliably and accurately analyze the available images. Combined with the sheer volume of data acquired on a daily basis, the current dearth of - computational tools means that most of the relevant information contained in today's clinical brain scans simply remains unused. - - 2021-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Denmark - - - TRABIT - - - H2020-MSCA-ITN-2017 - - - 765148 - - - - - QUEEN MARY UNIVERSITY OF LONDON - UNIVERSITA DEGLI STUDI DI TRIESTE - ILLYCAFFE S.P.A - CENTER ODLICNOSTI ZA BIOSENZORIKO,INSTRUMENTACIJO IN PROCESNO KONTROLO ZAVOD - BIOREALIS SRO - - - EUR 1 335 986,28 - - - Imprinted Polymers as Coffee Sensors - - - EUR 1 335 986,28 - - - United Kingdom - Italy - Italy - Slovenia - Slovakia - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Food quality is a global key priority area where technological advances in terms of quality control have been limited. The aim of the IPCOS Network is to bring innovation to the field of food quality by offering an - international, interdisciplinary and intersectorial doctoral training programme that will target the development of chemical sensors, using the molecular imprinting technology, for application in the coffee industry, focusing on three main targets: - chlorogenic acids, cafestol and kaurene terpenes, caffeine and its metabolites, all of which have been shown to have an impact on consumers’ health. This project brings together 2 academic teams, 1 large international company, 1 SME and one - non-profit research centre of excellent, supported by 4 associated teams, with a very multidisciplinary and multisectorial expertise. The IPCOS training program will require ESRs to work 50% of their time in industry, providing them with a set of - unique scientific and transferable skills that will match both public and private sector needs, together with a strong development of innovation and entrepreneurship ethos, therefore considerably enhancing their career perspectives. All researchers - will aim to achieve a doctoral degree at the end of their training. As a result of the close collaborative links, IPCOS will strengthen the innovation capacity of universities/research institutes to commercially exploit their research and enhance the - research potential and competitiveness of European companies and SMEs. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-EID - Marie Skłodowska-Curie Innovative Training Networks (ITN-EID) - - - MSCA-ITN-EID - European Industrial Doctorates - - - United Kingdom - - - IPCOS - - - H2020-MSCA-ITN-2014 - - - 642014 - - - - - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH - - - EUR 150 000 - - - TOF PET With Strip SiPMs - - - EUR 150 000 - - - Switzerland - Switzerland - - - Research Organisations - Research Organisations - - TWIST will build detector modules for PET scanners that offer high sensitivity together with precise position and time resolution. TWIST will deliver high-resolution PET images with low background using a lower dosage of - radio-tracer. The breakthrough is obtained due to the successful development of the new Strip Silicon PhotoMultiplier (SSiPM) within the ERC TICAL project. - - 2019-06-30, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Switzerland - - - TWIST - - - ERC-2017-PoC - - - 780151 - - - - - TECHNISCHE UNIVERSITEIT EINDHOVEN - TECHNISCHE UNIVERSITEIT EINDHOVEN - - - EUR 150 000 - - - New chemical building blocks for de-icing and anti-icing of car windows - - - EUR 150 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Ice accretion of car windshields is a road safety concern in fall and wintertime as frost impairs the vision of drivers that do not sufficiently de-ice their car windshields, which may cause serious road accidents. Windshield - washer fluids are crucially important for rapid car windshield de-icing which is most efficient through a combination of thermal, mechanical, and chemical action; i.e., local heating, scraping, and the application of appropriate windshield washer - fluids. At present, windshield washer fluids rely solely on colligative antifreezes. The current formulations are (highly) flammable which requires precautionary measures in stores and cars, and the ethanol used is derived from sugarcane which is a - valuable food resource. The challenge is to develop a commercially viable solution to replace these colligative antifreezes by an innovative screenwash formulation that is highly effective, but not flammable, does not present a health risk, and does - not use food resources. In ‘PRicelessCOAT’ scientists will develop new biocompatible and biodegradable chemical building blocks for de-icing and anti-icing of car windows. - - 2019-06-30, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Netherlands - - - PRicelessCOAT - - - ERC-2017-PoC - - - 780160 - - - - - UNIVERSITEIT GENT - UNIVERSITEIT GENT - - - EUR 1 498 469 - - - Microclimatic buffering of plant responses to macroclimate warming in temperate forests - - - EUR 1 498 469 - - - Belgium - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Recent global warming is acting across ecosystems and threatening biodiversity. Yet, due to slow responses, many biological communities are lagging behind warming of the macroclimate (the climate of a large geographic region). - The buffering of microclimates near the ground measured in localized areas, arising from terrain features such as vegetation and topography, can explain why many species are lagging behind macroclimate warming. However, almost all studies ignore the - effects of microclimatic buffering and key uncertainties still exist about this mechanism. Microclimates are particularly evident in forests, where understorey habitats are buffered by overstorey trees. In temperate forests, the understorey contains - the vast majority of plant diversity and plays an essential role in driving ecosystem processes. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Belgium - - - FORMICA - - - ERC-2017-STG - - - 757833 - - - - - UNIVERSITAET LEIPZIG - UNIVERSITAET LEIPZIG - - - EUR 1 341 250 - - - Higher Co-dimension Singularities: Minimal Surfaces and the Thin Obstacle Problem - - - EUR 1 341 250 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Singular solutions to variational problems and to partial differential equations are naturally ubiquitous in many contexts, and among these minimal surfaces theory and free boundary problems are two prominent examples both for - their analytical content and their physical interest. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - HiCoS - - - ERC-2017-STG - - - 759229 - - - - - FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION - FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION - - - EUR 1 500 000 - - - Cell-to-cell variability during symmetry breaking in organoid development - - - EUR 1 500 000 - - - Switzerland - Switzerland - - - Research Organisations - Research Organisations - - Cell-to-cell variability is an inherent property of populations of cells. As a starting point for symmetry breaking events, it is also an essential building block for self-organised pattern forming systems. Nonetheless, the - sources and roles of cell-to-cell variability in symmetry-breaking events during collective cell behavior await a quantitative and mechanistic understanding. To obtain these insights, we will use a model system of intestinal organoids, which - recapitulates most of the processes of morphogenesis and patterning observed in intestinal tissue. In this system, the symmetry-breaking event is observed when, despite all single cells in a growing organoid are exposed to uniform environments, only - a fraction of cells acquires specific cell fates, generating asymmetric structures such as crypts and villi. This project aims to uncover the extent, sources, and consequences of cell heterogeneity. To this end, we will use advanced multiplexed - imaging of intestinal stem cells in 3D organoid development to monitor quantitatively the behaviour of each single cell in the system. Initially, we will identify potential sources of cell-to-cell variability, such as the microenvironment or the cell - cycle. Next, we will create models to identify predictors of symmetry breaking and patterning. In parallel, we will determine the extent of cellular heterogeneity by single-cell RNA sequencing during organoid formation. Finally, we will test if - cellular heterogeneity is necessary and sufficient to induce symmetry-breaking of intestinal organoids by experimentally inducing and perturbing cell-to-cell variability. Thus, this research proposal will address a major question in developmental - biology and collective cell behavior, namely how single cells exposed to a uniform growth-promoting environment generate asymmetric structures. Moreover, it will unravel how local interactions between single cells give rise to emergent, - self-organized patterns. - - 2023-09-30, Grant Agreement signed - - - 2018-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Switzerland - - - SymBreakOrganoid - - - ERC-2017-STG - - - 758617 - - - - - KING'S COLLEGE LONDON - KING'S COLLEGE LONDON - - - EUR 1 499 999 - - - Dynamical Redesign of Biomolecular Networks - - - EUR 1 499 999 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Enzymes created by Nature are still more selective and can be orders of magnitude more efficient than man-made catalysts, in spite of recent advances in the design of de novo catalysts and in enzyme redesign. The optimal - engineering of either small molecular or of complex biological catalysts requires both (i) accurate quantitative computational methods capable of a priori assessing catalytic efficiency, and (ii) molecular design principles and corresponding - algorithms to achieve, understand and control biomolecular catalytic function and mechanisms. Presently, the computational design of biocatalysts is challenging due to the need for accurate yet computationally-intensive quantum mechanical - calculations of bond formation and cleavage, as well as to the requirement for proper statistical sampling over very many degrees of freedom. Pioneering enhanced sampling and analysis methods have been developed to address crucial challenges bridging - the gap between the available simulation length and the biologically relevant timescales. However, biased simulations do not generally permit the direct calculation of kinetic information. Recently, I and others pioneered simulation tools that can - enable not only accurate calculations of free energies, but also of the intrinsic molecular kinetics and the underlying reaction mechanisms as well. I propose to develop more robust, automatic, and system-tailored sampling algorithms that are optimal - in each case. I will use our kinetics-based methods to develop a novel theoretical framework to address catalytic efficiency and to establish molecular design principles to key design problems for new bio-inspired nanocatalysts, and to identify and - characterize small molecule modulators of enzyme activity. This is a highly interdisciplinary project that will enable fundamental advances in molecular simulations and will unveil the physical principles that will lead to design and control of - catalysis with Nature-like efficiency. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - BioNet - - - ERC-2017-STG - - - 757850 - - - - - Eidgenössische Technische Hochschule Zürich - Eidgenössische Technische Hochschule Zürich - - - EUR 1 500 000 - - - Majorana neutrino discovery strategy with CMS - - - EUR 1 500 000 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The Large Hadron Collider at CERN is successfully operating at a record-breaking energy and is expected to deliver an enormous dataset of 300/fb of proton-proton collisions in the next 6 years. I propose to take advantage of - both the unprecedented collision energy and the large number of events to be recorded in order to search for signs of new particles which could uncover the nature of dark matter, provide an explanation for the matter-antimatter asymmetry of the - universe or answer questions about the origin of neutrino masses. To achieve this, I will build on my expertise devising and organizing new physics searches with leptons and will establish and lead a new multi-signature research programme at the CMS - experiment. This programme will exploit both the intensity and energy frontiers opening up at the LHC and can be further expanded at the high-luminosity LHC (HL-LHC). Since the masses and couplings of the new particles are unconstrained, my proposed - search strategy will be such that a wide mass range will be covered also encompassing many orders of magnitude in the coupling strength. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Switzerland - - - MajorNet - - - ERC-2017-STG - - - 758316 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 499 903 - - - Optoelectronic of narrow band gap nanocrystals - - - EUR 1 499 903 - - - France - France - - - Research Organisations - Research Organisations - - Over the past decades, silicon became the most used material for electronic, however its indirect band gap limits its use for optics and optoelectronics. As a result alternatives semiconductor such as III-V and II-VI materials - are used to address a broad range of complementary application such as LED, laser diode and photodiode. However in the infrared (IR), the material challenge becomes far more complex. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - blackQD - - - ERC-2017-STG - - - 756225 - - - - - FORSCHUNGSZENTRUM JULICH GMBH - FORSCHUNGSZENTRUM JULICH GMBH - - - EUR 1 482 672 - - - Impact and interaction of prophage elements in bacterial host strains of biotechnological relevance - - - EUR 1 482 672 - - - Germany - Germany - - - Research Organisations - Research Organisations - - Phages, viruses that prey on bacteria, are the most abundant and diverse inhabitants of the Earth. Temperate bacteriophages are able to integrate into the host genome and maintain as prophages a long-term association with - their host. Illustrated by the development of mutually beneficial traits, this close interaction between host and virus has significantly shaped bacterial evolution. However, the immense genetic resources of phage genomes still remain almost - unexplored. For the transition to a sustainable bioeconomy, we strongly depend on microbes as hosts for the production of value-added compounds. PRO_PHAGE will exploit recent advances in next-generation sequencing (NGS), single-cell analysis, and - high-throughput (HT) phenotyping to evaluate the impact of phage elements on host fitness and to use this knowledge for the improvement of future metabolic engineering approaches. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - PRO_PHAGE - - - ERC-2017-STG - - - 757563 - - - - - UNIVERSITEIT GENT - UNIVERSITEIT GENT - - - EUR 149 609 - - - Miniature on-chip Raman spectrometer for personal volatile organic compound (VOC) monitoring - - - EUR 149 609 - - - Belgium - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - We aspire to build the smallest and most lightweight Raman spectrometer in the world, with a target size of 5x10x1 mm3 and a weight of only 0.1 g. The innovation builds on the combination of three key results of the ERC - Advanced Grant project InSpectra (2011-2017): 1. Demonstration of Nanophotonic waveguide Enhanced Raman Spectroscopy (NERS); 2. Demonstration of a novel on-chip Fourier Transform Spectrometer (FTS); 3. Demonstration of the integration of III-V light - sources on a silicon platform through bonding or transfer printing technologies. By using a standard CMOS process toolset for fabricating the Raman spectrometer, a cost-effective and high yield product can be guaranteed with a price level at least an - order of magnitude lower than current commercial systems. The exceptional form factor of the spectrometer will generate a rich variety of innovative applications of Raman spectroscopy. A spectrometer this small can be implanted, incorporated in - smartphones or smartwatches and fits into textiles, drones etc. In this ERC PoC project, we will build this miniature spectrometer and use it for the target application of detecting volatile organic compounds (VOC) for personal safety monitoring, - both at work and at home. - - 2019-06-30, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Belgium - - - MIRASPEC - - - ERC-2017-PoC - - - 780718 - - - - - UNIVERSITEIT GENT - UNIVERSITEIT GENT - - - EUR 1 476 250 - - - Everyday Writing in Graeco-Roman and Late Antique Egypt (I - VIII AD). A Socio-Semiotic Study of Communicative Variation - - - EUR 1 476 250 - - - Belgium - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This five-year project aims to generate a paradigm shift in the understanding of Graeco-Roman and Late Antique communication. Non-literary, ‘documentary’ texts from Ancient Egypt such as letters, petitions and contracts have - provided and continue to provide a key witness for our knowledge of the administration, education, economy, etc. of Ancient Egypt. This project argues that since documentary texts represent originals, their external characteristics should also be - brought into the interpretation: elements such as handwriting, linguistic register or writing material transmit indirect social messages concerning hierarchy, status, and power relations, and can therefore be considered ‘semiotic resources’. The - project’s driving hypothesis is that communicative variation – variation that is functionally insignificant but socially significant (e.g. there are ~ there’s ~ it’s a lot of people) – enables the expression of social meaning. The main aim of this - project is to analyse the nature of this communicative variation. To this end, a multidisciplinary team of six researchers (one PI, one post-doc, and four PhD’s) will apply recent insights form socio-semiotic and socio-linguistic theory to a corpus - of Graeco-Roman and Late Antique documentary texts (I – VIII AD) by means of a three-level approach: (i) an open-access database of annotated documentary texts will be created; (ii) the ‘semiotic potential’ of the different semiotic resources that - play a role in documentary writing will be analysed; (iii) the interrelationships between the different semiotic resources will be studied. The project will have a significant scientific impact: (i) it will be the first to offer a holistic - perspective towards the ‘meaning’ of documentary texts; (ii) the digital tool will open up new ways to investigate Ancient texts; (iii) it will make an important contribution to current socio-semiotic and socio-linguistic research; (iv) it will - provide new insights about humans as social beings. - - 2023-05-31, Grant Agreement signed - - - 2018-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Belgium - - - EVWRIT - - - ERC-2017-STG - - - 756487 - - - - - Institute of Science and Technology Austria - Institute of Science and Technology Austria - - - EUR 1 446 542 - - - Circuits of Visual Attention - - - EUR 1 446 542 - - - Austria - Austria - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The evolutionary arms race has optimized and shaped the way animals attend to relevant sensory stimuli in an ever-changing environment. This is a complex task, because the vast majority of sensory experiences are not relevant. - In humans, attentional disorders are a serious public health concern because of its high prevalence, but its causes are mostly unknown. In this proposal, I will explore the neuronal mechanisms used by the nervous system to attend visual cues to - enable appropriate behaviors. - - - 2022-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Austria - - - Daphne - - - ERC-2017-STG - - - 756502 - - - - - KOBENHAVNS UNIVERSITET - KOBENHAVNS UNIVERSITET - - - EUR 1 499 695 - - - Manifesting the Simplicity of Scattering Amplitudes - - - EUR 1 499 695 - - - Denmark - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - I propose a program of research that may forever change the way that we understand and use quantum field theory to make predictions for experiment. This will be achieved through the advancement of new, constructive frameworks - to determine and represent scattering amplitudes in perturbation theory in terms that depend only on observable quantities, make manifest (all) the symmetries of the theory, and which can be efficiently evaluated while minimally spoiling the - underlying simplicity of predictions. My research has already led to the discovery and development of several approaches of this kind. - - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Denmark - - - AMPLITUDES - - - ERC-2017-STG - - - 757978 - - - - - DOUGLAS CONNECT GMBH - - - EUR 187 419,60 - - - ADVerse outcome Network for non-mutagenic CarcinogEns - - - EUR 187 419,60 - - - Switzerland - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The field of toxicology is evolving from purely descriptive to a highly data‐rich science. To structure this large amount of data and in this way make the usage more effective for the safety assessors, the concept of adverse - outcome pathways was established providing a means of understanding how chemicals induce adverse effects through their toxicity pathways and modes of action. However, there are some doubts if the one initiating event - one adverse outcome - relationship enforced on AOPs by the OECD guideline is able to cover more complex adverse effects like hepatocellular carcinoma resulting from non-mutagenic chemical exposure. Therefore, the ADVaNCE project will demonstrate based on the just - mentioned example that combining all existing knowledge into an adverse outcome network formed by interlinked AOPs is needed to cover all the pathways and intervention points activated in order to contribute to the development of hepatocellular - carcinomas. Computational approaches will be used to extract important key events and their relationships from existing data sources and the relevant literature. These will be compared with existing AOPs and further experimental validation will be - started. The computational and experimental result will finally guide the development of an integrated testing strategy completely based on in silico and in vitro data, which development and validation regarding regulatory usage will be continued - after the project. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-SE - Society and Enterprise panel - - - Switzerland - - - ADVaNCE - - - H2020-MSCA-IF-2016 - - - 750195 - - - - - THE UNIVERSITY OF MANCHESTER - - - EUR 195 454,80 - - - Adopting open innovation 2.0 by integrating responsible innovation for sustainability - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Due to both academic and family commitments over the coming year 1st October 2017 is the chosen indicative start date for this project - - 2019-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - OpenInnovationImpact - - - H2020-MSCA-IF-2016 - - - 749423 - - - - - CARDIFF UNIVERSITY - UNIVERSITAT POLITECNICA DE CATALUNYA - CONTROL INTEL-LIGENT DE L'ENERGIA SCCL - UNIVERSIDADE DO PORTO - EFACEC ENERGIA - MAQUINAS E EQUIPAMENTOS ELECTRICOS SA - DANMARKS TEKNISKE UNIVERSITET - KATHOLIEKE UNIVERSITEIT LEUVEN - CG HOLDINGS BELGIUM NV - ELIA SYSTEM OPERATOR - - - EUR 3 893 199,84 - - - Innovative tools for offshore wind and DC grids - - - EUR 3 893 199,84 - - - United Kingdom - Spain - Spain - Portugal - Portugal - Denmark - Belgium - Belgium - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Europe’s power system has seen significant changes in recent decades, notably the development of renewable energy ources. However, this transition is far from complete, and further changes are essential to make our energy - system ready to play its part in realising the climate goals set at COP21. At present, renewable energy sources are increasing their share of electricity generation. This is particularly the case for offshore wind energy. InnoDC's 14 participants - prepare 15 early career researchers to play their role in the energy transition that will take place over the next 20-40 years. - - 2021-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - InnoDC - - - H2020-MSCA-ITN-2017 - - - 765585 - - - - - FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION - FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION - - - EUR 1 500 000 - - - Biophysical mechanisms of long-range transcriptional regulation - - - EUR 1 500 000 - - - Switzerland - Switzerland - - - Research Organisations - Research Organisations - - In mammals, transcriptional control of many genes relies on cis-regulatory elements such as enhancers, which are often located tens to hundreds of kilobases away from their cognate promoters. Functional interactions between - distal regulatory elements and target promoters require mutual physical proximity, which is linked to the three-dimensional structure of the chromatin fiber. Chromosome conformation capture studies revealed that chromosomes are partitioned into - Topologically Associating Domains (TADs), sub-megabase domains of preferential physical interactions of the chromatin fiber. Genetic evidence showed that TAD boundaries restrict the genomic range of enhancer-promoter communication, and that - interactions between regulatory sequences within TADs are further fine-tuned by smaller-scale structures. However, the mechanistic details of how physical interactions translate into transcriptional outputs are totally unknown. Here we propose to - explore the biophysical mechanisms that link chromosome conformation and long-range transcriptional regulation using molecular biology, genetic engineering, single-cell experiments and physical modeling. We will measure chromosomal interactions in - single cells and in time using a novel method that relies on an enzymatic process in vivo. Genetic engineering will be used to establish a cell system that allows quantitative measurement of how enhancer-promoter interactions relate to transcription - at the population and single-cell levels, and to test the effects of perturbations without confounding effects. Finally, we will develop physical models of promoter operation in the presence of distal enhancers, which will be used to interpret the - experimental data and formulate new testable predictions. With this integrated approach we aim at providing an entirely new layer of description of the general principles underlying transcriptional control, which could establish new paradigms for - research in epigenetics and gene regulation. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Switzerland - - - BioMeTRe - - - ERC-2017-STG - - - 759366 - - - - - WEIZMANN INSTITUTE OF SCIENCE - WEIZMANN INSTITUTE OF SCIENCE - - - EUR 1 493 803 - - - Realizable Advanced Cryptography - - - EUR 1 493 803 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In a free society, there is persistent tension between utility and privacy. Citizens have the basic right to keep their personal information private. However, sometimes keeping our data private could significantly reduce our - ability to use this data to benefit ourselves or society. This tension is multiplied many times over in our modern data driven society, where data is utilized using remote algorithms. - - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Israel - - - REACT - - - ERC-2017-STG - - - 756482 - - - - - UNIVERSITAET BASEL - UNIVERSITAET BASEL - - - EUR 1 158 403 - - - Engineering Topological Phases and Excitations in Nanostructures with Interactions - - - EUR 1 158 403 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The main goal of this theory project is to propose engineered topological phases emerging only in strongly interacting systems and to identify the most feasible systems for experimental implementation. First, we will focus on - setups hosting topological states localized at domain walls in one-dimensional channels such as parafermions, which are a new class of non-Abelian anyons and most promising candidates for topological quantum computing schemes. Second, in the - framework of weakly coupled wires and planes, we will develop schemes for novel fractional topological phases in two- and three-dimensional interacting systems. To achieve these two goals, my team will identify necessary ingredients such as strong - electron-electron interactions, helical magnetic order, or crossed Andreev proximity-induced superconductivity and address each of them separately. Later, we combine them to lead us to the desired topological phases and states. On our way to the main - goal, as test cases, we will also study non-interacting analogies of the proposed effects such as Majorana fermions and integer topological insulators and pay close attention to the rapid experimental progress to come up with the most feasible - proposals. We will study transport properties, scanning tunneling and atomic force microscopy. Especially for systems driven out of equilibrium, we will develop a Floquet-Luttinger liquid technique. We will explore the stability of engineered - topological phases, error rates of topological qubits based on them, and computation schemes allowing for a set of universal qubit gates. We will strive to find a reasonable balance between topological stability and experimental feasibility of - setups. Our main theoretical tools are Luttinger liquid techniques (bosonization and renormalization group), Green functions, Floquet formalism, and numerical simulations in non-interacting test models. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Switzerland - - - ETOPEX - - - ERC-2017-STG - - - 757725 - - - - - WEIZMANN INSTITUTE OF SCIENCE - WEIZMANN INSTITUTE OF SCIENCE - - - EUR 1 442 360 - - - A Theory for Understanding, Designing, and Training Deep Learning Systems - - - EUR 1 442 360 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The rise of deep learning, in the form of artificial neural networks, has been the most dramatic and important development in machine learning over the past decade. Much more than a merely academic topic, deep learning is - currently being widely adopted in industry, placed inside commercial products, and is expected to play a key role in anticipated technological leaps such as autonomous driving and general-purpose artificial intelligence. However, our scientific - understanding of deep learning is woefully incomplete. Most methods to design and train these systems are based on rules-of-thumb and heuristics, and there is a drastic theory-practice gap in our understanding of why these systems work in practice. - We believe this poses a significant risk to the long-term health of the field, as well as an obstacle to widening the applicability of deep learning beyond what has been achieved with current methods. - - 2023-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Israel - - - THUNDEEP - - - ERC-2017-STG - - - 754705 - - - - - UNIVERSITY OF DURHAM - UNIVERSITY OF DURHAM - - - EUR 1 499 557 - - - A new vantage point on how gas flows regulate the build-up of galaxies in the early universe - - - EUR 1 499 557 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Galaxies reside within a web of gas that feeds the formation of new stars. Following star formation, galaxies eject some of their gas reservoir back into this cosmic web. This proposal addresses the fundamental questions of - how these inflows and outflows regulate the evolution of galaxies. My research team will tackle two key problems: 1) how gas accretion regulates the build-up of galaxies; 2) how efficiently outflows are in removing gas from star-forming regions. To - characterise these flows across five billion years of cosmic history, we will pursue cutting-edge research on the halo gas, which is the material around the central galaxies, within dark matter halos. We will focus on scales ranging from a few - kiloparsecs, where outflows originate, up to hundreds of kiloparsecs from galaxies, where inflows and outflows have visible impacts on halos. We will attack this problem using both simulations and observations with the largest telescopes on the - ground and in space. With novel applications of absorption spectroscopy, we will gain a new vantage point on the astrophysics of these gas flows. Exploiting unprecedented datasets that I am currently assembling thanks to ground-breaking developments - in instrumentation, we will directly connect the properties of halo gas to those of the central galaxies, investigating the impact that the baryonic processes probed in absorption have on galaxies seen in emission. In parallel, using new hydrodynamic - simulations and radiative transfer calculations, we will go beyond present state-of-the-art methodologies to unveil the theory behind the origin of these gas flows, a crucial aspect to decode the physics probed by our observations. As a result of - this powerful synergy between observations and simulations, this programme will provide the most advanced analysis of the impact that inflows and outflows have on galaxy evolution, shaping the direction of future work at 40m telescopes and the next - generation of cosmological simulations. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - FEEDGALAXIES - - - ERC-2017-STG - - - 757535 - - - - - UNIVERSITAET BASEL - UNIVERSITAET BASEL - - - EUR 1 488 387,50 - - - Phononic Circuits: manipulation and coherent control of phonons - - - EUR 1 488 387,50 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In the last decades, the power to control photons and electrons paved the way for extraordinary technological developments in electronic and optoelectronic applications. The same degree of control is still lacking with - quantized lattice vibrations, i.e. phonons. Phonons are the carriers of heat and sound. The understanding and ability to manipulate phonons as quantum particles in solids enable the control of coherent phonon transport, which is of fundamental - interest and could also be exploited in applications. Logic operations can be realized with the manipulation of phonons both in their coherent and incoherent form in order to switch, amplify, and route signals, and to store information. If brought to - a mature level, phononic devices can become complementary to the conventional electronics, opening new opportunities. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Switzerland - - - PHONUIT - - - ERC-2017-STG - - - 756365 - - - - - OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN - OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN - - - EUR 1 499 475 - - - SPD nanostructured magnets with tuneable properties - - - EUR 1 499 475 - - - Austria - Austria - - - Research Organisations - Research Organisations - - The decrease of weight and the increase of efficiency of magnetic components are essential for the reduction of CO2-emission and an improvement of their performance. Nanostructuring can dramatically improve the magnetic - properties of soft and hard magnetic materials, hence opening up entirely new possibilities for the development of novel magnets. Nanocomposite magnets, for example, have been the focus of research since two decades. One of the remaining key - challenges is to synthesize bulk nanostructured magnets of a reasonable size. In this project, this challenge is explicitly addressed and the potential to fabricate bulk nanostructured magnets by severe plastic deformation (SPD) as an innovative - processing route is evaluated. The aim of the project is not only to synthesize different nanostructured magnets by SPD, but also to tailor their microstructure to attain the desired magnetic properties. It has been shown by the applicant that the - magnetic properties of SPD processed nanocrystalline materials can be modified in wide range by decomposition of metastable solid solutions. By using different immiscible systems, decomposition mechanisms and annealing treatments, unique - nanostructures can be obtained and the magnetic properties can be optimized. Through the choice of different magnetic starting materials, such as soft, hard and antiferromagnetic-ferromagnetic powders, different types of hard magnetic nanocomposites - will also be obtained. Fine tuning of the microstructure and resulting magnetic properties through adjustments in the composition, SPD processing parameters and annealing treatments is planned. The project systematically addresses the entire process - from the synthesis to the in-depth microstructural characterization by electron microscopy and atom probe tomography. In combination with simultaneous measurements of magnetic properties, the newly developed knowledge will be used to improve the - performance of SPD processed nanostructured magnets. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Austria - - - SpdTuM - - - ERC-2017-STG - - - 757333 - - - - - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - - - EUR 195 454,80 - - - Ultrathin Mixed Matrix Membranes (MMMs) Derived from Metal-Organic Framework (MOF) Nanosheets for Organic Solvent Nanofiltration (OSN) - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Energy efficiency is at the heart of the EU’s 2020 Strategy for smart, sustainable and inclusive growth. Organic solvent nanofiltration (OSN) technology is an emerging technology that can potentially achieve organic liquid - separation on a molecular scale with less than half the energy consumption than conventional distillation processes. The main obstacle is the lack of OSN membrane materials with three key properties: high flux; high selectivity; and excellent - stability. This project seeks to develop ultrathin OSN membranes comprising metal-organic framework (MOF) nanosheets in ultrathin polymer matrix in the form of mixed matrix membranes (MMMs). This research work is based on combining recent technology - breakthroughs in: (i) 1-nm-thick MOF nanosheet based molecular sieve membranes, developed by the Applicant; and (ii) highly cross-linked sub-10-nm-thick OSN polymer membranes developed by the Host group. This is a timely and highly original research - concept to create a new generation of high performances, and brings the full potential of MOF materials to the field of OSN membranes to produce highly stable OSN membranes with ultrafast solvent permeation and finely tunable (molecular weight - cut-off) MWCO curves. In addition, the in-depth studies on controllable synthesis of MOF structures, rational design and synthesis of polymer networks, and microstructural optimization of MOF-polymer composites are expected to lead to - application-oriented fabrication of high-performance membranes and functional thin films for a wide range of applications. This project will bring together the complementary expertise of both the applicant and the Host with the aim of developing - mutually-beneficial research cooperation between Europe and China. This high-quality and highly innovative research will open up the optimum career possibilities for the applicant by broadening his research horizons, enriching his research - experience, and strengthening his network with European colleagues. - - 2019-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - MONSON - - - H2020-MSCA-IF-2015 - - - 705842 - - - - - LUNDS UNIVERSITET - LUNDS UNIVERSITET - - - EUR 1 500 000 - - - How our adaptive immune system separates “self” from “foreign” – a physicochemical study of binding in cell contacts - - - EUR 1 500 000 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - How can our immune system efficiently fight foreign pathogens at the same time as it is selective enough to leave our own cells alone? This, so called antigen discrimination, is still not understood on a molecular level. I - will here illuminate this question by developing a physicochemical understanding of how T-cell receptors (TCRs) bind peptide-loaded major histocompatibility complexes (pMHCs), and importantly, how this differs for pMHC displaying self and foreign - peptides. The interaction between TCRs and pMHCs on contacting immune cells is the first step in initiating an adaptive immune response. However, binding between membrane-anchored TCR and pMHC is a challenging physicochemical problem that has not - been solved, and the binding kinetics is strongly affected by the membrane. Well-controlled measurements between TCR and pMHC under relevant conditions are needed to better understand the TCR/pMHC kinetics. A key discovery to achieve this is a method - recently developed by me, which allows for extremely weak protein-protein interactions in contacting cells to be measured. I will in this project, backed up by immunologist in Oxford and theoretical chemists in Lund, build on this breakthrough and - for the first time measure the binding kinetics between TCR in model cell membranes and pMHC on single cells, and how binding varies between self and foreign pMHC. Parameters such as adhesion molecules, applied force on the bond, the co-receptor CD4 - and TCR clustering are all crucial for proper T-cell signalling, but their influence on the TCR/pMHC binding kinetics is unknown, and will here be studied. The obtained data will finally be used to evaluate, and improve on, kinetic models of antigen - discrimination. Complemented with molecular dynamics simulations this altogether opens up for a fundamental understanding of binding between membrane-anchored molecules in general, and how this affects the TCR/pMHC interaction and antigen - discrimination in particular. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Sweden - - - SELFOR - - - ERC-2017-STG - - - 757797 - - - - - UNIVERSITY OF YORK - - - EUR 183 454,80 - - - Heterogeneous Effects of Fiscal Consolidation on Firms' Balance Sheets - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The global financial crisis and slow ensuing recovery have put severe strains on the fiscal positions of many OECD countries, raising serious concerns about fiscal sustainability, especially in the Euro Area. The challenge - facing these countries is how to bring debt down to safer levels in the face of a weak recovery. Several EU governments undertook large fiscal consolidations plans that involved a combination of spending cuts and tax hikes, aiming at sustainably - reducing public deficits and debt. - - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - FLASH - - - H2020-MSCA-IF-2016 - - - 747191 - - - - - TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY - TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY - BEN-GURION UNIVERSITY OF THE NEGEV - INTERDISCIPLINARY CENTER (IDC) HERZLIYA - - - EUR 1 903 833 - - - New Techniques for Secure Computation - - - EUR 1 903 833 - - - Israel - Israel - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Secure computation is a general-purpose tool for processing sensitive data without compromising its - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Israel - - - NTSC - - - ERC-2016-ADG - - - 742754 - - - - - AARHUS UNIVERSITET - AARHUS UNIVERSITET - - - EUR 1 499 406 - - - Measurement-based dynamic control of mesoscopic many-body systems - - - EUR 1 499 406 - - - Denmark - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Quantum control is an ambitious framework for steering dynamics from initial states to arbitrary desired final states. It has over the past decade been used extensively with immense success for control of low- dimensional - systems in as varied fields as molecular dynamics and quantum computation. Only recently have efforts been initiated to extend this to higher-dimensional many-body systems. Most generic quantum control schemes to date, however, put quite heavy - requirements on the controllability of either the system Hamiltonian or a set of measurement operators. This will in many realistic scenarios prohibit an efficient realization. - - 2020-04-30, ongoing project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Denmark - - - MECTRL - - - ERC-2014-STG - - - 639560 - - - - - UNIVERSIDAD DE ZARAGOZA - UNIVERSIDAD DE ZARAGOZA - - - EUR 1 498 636 - - - Is your heart aging well? A systems biology approach to characterize cardiac aging from the cell to the body surface - - - EUR 1 498 636 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Europe is facing a striking change in its demographics with an increasingly larger proportion of citizens aged 65 years and over. Aging is characterized by a progressive decline in the physiological functions of the body, with - very notable effects on the heart. These effects are associated with a higher prevalence of arrhythmias, which, on top of deteriorating quality of life, increase the risk of other cardiovascular diseases like stroke, heart failure and neurological - sequelae. Investigations targeting cardiac aging have often focused on assessing the effects of a specific contributing factor, at a single evaluation scale (molecular, cell, tissue, organ) and in many cases using animal species not relevant to - humans in terms of aging mechanisms. MODELAGE proposes a multi-scale, multi-factorial research that is expected to make an important step in the characterization of human heart aging at both the population and individual levels. MODELAGE will work on - an integrative methodological framework in which in silico modeling will be combined with in vitro cell and tissue analysis and in vivo electrocardiographic evaluation to investigate how cardiac aging manifests at a range of scales, from cell to body - surface, and how electrical, structural and autonomic alterations contribute to such manifestations in humans. Indices describing spatio-temporal dynamics of cardiac electrophysiology will be evaluated in a population of young to senescent - individuals using a novel feedback control approach. Inter-individual age-related variations in those indices will be assessed and correlated with markers of biological age (as opposed to chronological age). By investigating the mechanisms underlying - inter-individual differences in cardiac dynamics, MODELAGE will set links to arrhythmia susceptibility and will propose novel non-invasive markers to identify high-risk senescent individuals for which preventive anti-arrhythmic treatment should be - considered. - - 2020-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Spain - - - MODELAGE - - - ERC-2014-STG - - - 638284 - - - - - Lindum AS - - - EUR 196 400,40 - - - Developing commercial mushroom and vegetable production in an integrated food to waste to food biosystem. - - - EUR 196 400,40 - - - Norway - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - VegWaMus CirCrop aim to develop commercial mushroom and vegetable production in an integrated food to waste to food biosystem. The project objective is on closing loop between biogas production based on food wastes and reuse - of output after anaerobic digestion (AD). Mushroom and plant crop cultivation is usually performed through energy- and resource-intensive process (based on fossil or mineral resources), which generate wastes and the high CO2 footprint. Main emphasis - has been on plant crops, but integrated mushroom cultivation has been found to be highly interesting from botCircular approach in which organic wastes are utilized for both energy (renewable biogas) and crop production in a closed system. Foodwaste - treated in anaerobic digestion (AD) can be considered as a multicomponent organic fertiliser and byproduct for plant and mushroom cultivation substrate. Sustainable horticulture should reuse organic waste. The objectives of project will be achieved - by indicating mushroom species which will be grown commercially on substrate based on digestate and vegetable plant grown rousing spent mushroom substrate (after cultivation). Combined cultivation will be incorporated in sustainable greenhouse - environment in food to waste to food biosystem based on crop and substrate circulation. Lindum and associated partners have for several years developed more circular approach in which organic wastes are utilized for both energy(renewable biogas) and - crops production in a closed system. Launched in 2016, Grønt Skifte AS, will realize a large R&D greenhouse unit located next to a new large anaerobic digestion (AD) plant. The unit will investigate and demonstrate full utilization of output CO2, - heat and organic residue (digestate) from the AD. The large international interest towards the activities of Grønt Skifte is related to project’s potential for helping governments and communities meeting the Paris Agreement. This is the circular and - future way of food production. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-SE - Society and Enterprise panel - - - Norway - - - VegWaMus CirCrop - - - H2020-MSCA-IF-2016 - - - 751052 - - - - - AARHUS UNIVERSITET - KOBENHAVNS UNIVERSITET - THE UNIVERSITY OF WARWICK - UNIVERSIDAD NACIONAL DE LA PLATA - UNIVERSITE DE BORDEAUX - DANMARKS TEKNISKE UNIVERSITET - MINISTERIUM FUER UMWELT, LANDWIRTSCHAFT, ERNAEHRUNG, WEINBAU UND FORSTEN RHEINLAND- PFALZ - UNIVERSIDAD DE ZARAGOZA - INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE - UNIVERSIDADE CATOLICA PORTUGUESA - Instituto Superior de Agronomia - STICHTING VU - INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE - - - EUR 3 945 597,12 - - - MICROWINE - Microbial metagenomics and the modern wine industry - - - EUR 3 945 597,12 - - - Denmark - Denmark - United Kingdom - Argentina - France - Denmark - Germany - Spain - France - Portugal - Portugal - Netherlands - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - A diverse, complex, and poorly characterised community of microorganisms lies at the heart of the wine – an industry worth over €220 billion globally. These microorganisms play key roles at all stages of the viniculture and - vinification processes, from helping plants access nutrients from the soil, driving their health through protection against pathogens, to fermentation processes that transform the must into wine with its complex array of aromas and flavours. Given - this importance, an improved understanding of the microbial community and its interplay will have significant effects on the industry. In recent years, 'Next Generation' DNA sequencing has revolutionised many areas of biology, including microbiology, - through conferring the ability to characterise microbes on the deep community scale, through both ’shotgun’ and ’deep amplicon’ sequencing approaches. To exploit this power for the benefit of the wine industry, we propose MICROWINE, a 15 ESR Marie - Curie Actions European Training Network. The network is constructed as a close collaboration between industry and academic partners, around the theme of the microbial community’s role in the wine production process. Through combining microbial - metagenomic sequencing with powerful computation analyses, with metadata generated using techniques such as metabolomics and geochemistry, we will study the action of microbes from the plant protection and nutrition, through to wine fermentation - process, using samples collected from both Europe and beyond. We will further train the ESRs across a wide range of relevant disciplines, and maximise information transfer through multiple host and academic-industry cosupervision and secondments. In - this way, we anticipate contributing to the strength and scientific progress of the wine industry through training of a cohort of leading, interdisciplinary and tightly interconnected scientists at the forefront of modern microbiological, genomic, - computational and related techniques. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Denmark - - - MICROWINE - - - H2020-MSCA-ITN-2014 - - - 643063 - - - - - UNIVERSITAT ZURICH - SCUOLA IMT (ISTITUZIONI, MERCATI, TECNOLOGIE) ALTI STUDI DI LUCCA - GCF - GLOBAL CLIMATE FORUM EV - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - INSTITUT JOZEF STEFAN - LONDON CENTRE FOR MATHEMATICAL SCIENCES LBG - SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO SANT'ANNA - FONDATION NATIONALE DES SCIENCES POLITIQUES - INSTITUTE FOR ADVANCED SUSTAINABILITY STUDIES EV - THE UNIVERSITY OF SUSSEX - UNIVERSIDAD DE ZARAGOZA - THE YOUNG FOUNDATION LBG - SIGMA ORIONIS SA - FINANCE WATCH AISBL - PLUSVALUE - UNIVERSITY COLLEGE LONDON - - - EUR 3 270 646,74 - - - Distributed Global Financial Systems for Society - - - EUR 4 250 000 - - - Switzerland - Italy - Germany - France - Slovenia - United Kingdom - Italy - France - Germany - United Kingdom - Spain - United Kingdom - France - Belgium - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Research Organisations - Higher or Secondary Education Establishments - - The DOLFINS project addresses the global challenge of making the financial system better serve society by placing scientific evidence and citizens participation at the centre of the policy process in finance. The project - strives to give scientific evidence and citizens participation central roles in the policy process concerning finance. DOLFINS will focus on two crucial and interconnected policy areas that will shape the public debate in the coming 5 years: How to - achieve financial stability and how to facilitate the long-term investments required by the transition to a more sustainable, more innovative, less unequal and greener EU economy. The expected impact is to achieve crucial advances in reshaping the - policy process to overcome the financial and political crisis faced by the EU. We will deliver quantitative tools to evaluate policies aiming to tame systemic risk and to foster sustainable investing. The tools will be based on fundamental research - combining network models and algorithmic game theory with broader economic insights. This approach can provide a more satisfactory understanding of credit, risk and sustainable investments in an interconnected world. We will investigate how to engage - citizens in the early stage of the policy making process and will develop evidence-based narratives in order to better shape policies in the public interest. To this end, our project will take advantage of semantic web technologies, big data and ICT - in general. Given the highly technical nature of key issues in finance, we will explore how ICT and art can facilitate citizens’ engagement through innovative narratives, leading to better coordinated actions of stakeholders. - - 2018-02-28, ongoing project - - - 2015-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.2."> - - - FETPROACT-1-2014 - Global Systems Science (GSS) - - - RIA - Research and Innovation action - - - Switzerland - - - DOLFINS - - - H2020-FETPROACT-2014 - - - 640772 - - - - - ISTANBUL TEKNIK UNIVERSITESI - ECOLE NATIONALE SUPERIEURE ARTS INDUSTRIES TEXTILES - ANOTATO EKPAIDEYTIKO IDRIMA PEIRAIA TECHNOLOGIKOY TOMEA - KIVANC KIMYA SANAYII VE TICARET ANONIM SIRKETI - INLAS INTELEKTUALNA LASTNINA IN SVETOVANJE DOO - TEXNOLOGIES FOTONIKON KAI HLEKTRONIKON SYSTHMATVN AE - THE UNIVERSITY OF MANCHESTER - UNITED MEDICAL INNOVATION LTD - - - EUR 913 500 - - - Welding of E-Textiles for Interactive Clothing - - - EUR 1 206 000 - - - Turkey - France - Greece - Turkey - Slovenia - Greece - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The new field of science dealing with implementation of electronics to textiles in combination with informatics is known as e-textiles. This project proposal leads to knowledge transfer among partners in order to develop - innovative e-textile products for interactive protective clothing and footwear using welding technologies by bringing experts from different countries, sectors and disciplines together to focus their effort in innovative e-textile product designs. - - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Turkey - - - ETexWeld - - - H2020-MSCA-RISE-2014 - - - 644268 - - - - - UNIVERSITATEA ALEXANDRU IOAN CUZA DIN IASI - UNIVERSITATEA DIN CRAIOVA - UNIVERSITATEA DE VEST DIN TIMISOARA - UNIVERSITATEA DIN BUCURESTI - UNIVERSITATEA BABES BOLYAI - UNIVERSITATEA LUCIAN BLAGA DIN SIBIU - INSTITUTUL DE FIZICA ATOMICA - INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU FIZICA LASERILOR PLASMEI SI RADIATIEI - "INSTITUTUL NATIONAL DE CERCETARE -DEZVOLTARE PENTRU FIZICA SI INGINERIE NUCLEARA ""HORIA HULUBEI"" (IFIN-HH)" - INSTITUTUL DE STIINTE SPATIALE - - - EUR 118 316 - - - RESEARCHERS' NIGHT in ROMANIA. Do you speak science? - - - EUR 118 316,25 - - - Romania - Romania - Romania - Romania - Romania - Romania - Romania - Romania - Romania - Romania - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Research Organisations - - The general objective of the project is to promote scientific research in Romania and to share to general public the enthusiasm of professionals working in this field. - - - 2015-12-31, closed project - - - 2014-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.5."> - - - MSCA-NIGHT-2014 - European Researchers' Night (NIGHT) - - - CSA - Coordination and support action - - - Romania - - - RoTalkScience - - - H2020-MSCA-NIGHT-2014 - - - 633311 - - - - - SLOVENSKA ORGANIZACIA PRE VYSKUMNEA VYVOJOVE AKTIVITY ZDRUZENIE - SLOVENSKA AKADEMIA VIED - I-EUROPA SRO - CENTRUM VEDECKO TECHNICKYCH INFORMACII SLOVENSKEJ REPUBLIKY - - - EUR 150 000 - - - Festival of Science European Researchers' Night 2014 - 2015 in Slovakia - - - EUR 150 000 - - - Slovakia - Slovakia - Slovakia - Slovakia - - - Other - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - "Sovva, n.o. has been organising the festival of science Researchers´night in Slovakia since 2007. The recent festival featured more than 1000 researchers and attended by nearly 177000 visitors. To continue in this succesful - effort we have prepared the new concept for ERN 2014-15 with the following lead ideas: Science is Adventure and Experience the Science. The target is to challenge people to face the Science and to discover its beauty with aim to attracting the young - generation to study science. The festival will present the most interesting research findings in Slovakia by leading Slovak universities, research institutes of the Slovak Academy of Sciences as well as representatives of innovative companies - supporting R&D activities. The science shows will be held in shopping malls, but there will be also a number of side events in museums and observatories as well as discussions, lectures and various competitions. A wide range of activities will - cover all country´s territory (Bratislava, Banska Bystrica, Zilina, Kosice, Tatranska Lomnica). All festival venues in the five cities will offer opportunities to spend the day and night visiting the interesting presentations and lectures, test - scientific applications, get in touch with the latest research outcomes and to speak with researchers. Thanks to the direct discussions with them people can discover their ""human face"". Since efforts during the event and also during awareness - campaign will focus mostly on examples showing how interesting and important the career of researcher is, we believe the ERN 2014-15 will help us to tackle the still existing stereotypes about researchers and science and encouraging young people to - embark on scientific careers. To support the ERN impact, event venues will be linked through live streaming and as a member of Eusea we will use also this platform to provide the virtual and real connections between cities, venues and countries for - exchange and collaboration." - - 2015-11-30, closed project - - - 2014-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.5."> - - - MSCA-NIGHT-2014 - European Researchers' Night (NIGHT) - - - CSA - Coordination and support action - - - Slovakia - - - ERN14-15SVK - - - H2020-MSCA-NIGHT-2014 - - - 633288 - - - - - DRUSTVO ZNANOST.ORG - SVEUCILISTE U SPLITU - SVEUCILISTE U ZAGREBU FAKULTET ELEKTROTEHNIKE I RACUNARSTVA - - - EUR 107 430 - - - CRO-EU-REKA! Research For Innovation, Innovation For People - - - EUR 144 750 - - - Croatia - Croatia - Croatia - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - "The project “CRO-EU-REKA!” will carry out preparations, promotion, organization and impact assessment of the European Researchers' Night events to be organized in Zagreb and Split, the two largest cities in the Republic of - Croatia, on 26th September 2014 and 25th September 2015. - - - 2015-11-30, closed project - - - 2014-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.5."> - - - MSCA-NIGHT-2014 - European Researchers' Night (NIGHT) - - - CSA - Coordination and support action - - - Croatia - - - CRO-EU-REKA - - - H2020-MSCA-NIGHT-2014 - - - 633305 - - - - - ESCIENCIA EVENTOS CIENTIFICOS SL - UNIVERSIDAD DE ZARAGOZA - FUNDACION AGENCIA ARAGONESA PARA LA INVESTIGACION Y EL DESARROLLO - - - EUR 110 000 - - - European Reseearchers Night: Researchers in Real Life. - - - EUR 287 850 - - - Spain - Spain - Spain - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Other - - “Researchers in Real Life” is the project to show people of Aragon, researchers are common people and their work is in our daily life, in a festive mood with activities in City Center streets. After three years European - Researchers Night has become an important event in Saragossa. - - - 2015-11-30, closed project - - - 2014-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.5."> - - - MSCA-NIGHT-2014 - European Researchers' Night (NIGHT) - - - CSA - Coordination and support action - - - Spain - - - ESC - - - H2020-MSCA-NIGHT-2014 - - - 633260 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSITE DE STRASBOURG - UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - LATVIJAS UNIVERSITATE - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - INSTITUT JOZEF STEFAN - Kolektor Group d.o.o., vodenje in upravljanje družb - ELVESYS SAS - - - EUR 3 757 056,48 - - - Magnetics and Microhydrodynamics - from guided transport to delivery - - - EUR 3 757 056,48 - - - France - France - Spain - Germany - Latvia - Ireland - Slovenia - Slovenia - France - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - This multidisciplinary network entitled: “Magnetics and Microhydrodynamics - from guided transport to delivery” (MaMi) bridges the research fields of fluidics and magnetism, by taking advantage of magnetic forces to control - local flows and cargo transport inspired by biomimetic systems. Using magnetic sources, as well as high magnetic susceptibility liquids or nanostructures, devices with unique anti-fouling properties and non-slip boundary conditions can be realized. - Our scientific aim is to take advantage of such unique wall-less properties to create new applications of microfluidic technology for life sciences. The network assembles and interdisciplinary team of seven academic and five non-academic partners, - exposes all students to industrial environments, and ensures training at the frontiers of two well-established research fields, which are not commonly associated. Over the course of their projects, early stage researchers based in academic - institutions will experience working environments in at least 3 different countries. Training a new generation of researchers will bring new cutting-edge knowledge, and will ensure a high potential for industrial applications to promote EU - leadership. - - 2022-04-30, Grant Agreement signed - - - 2018-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - France - - - MAMI - - - H2020-MSCA-ITN-2017 - - - 766007 - - - - - AARHUS UNIVERSITET - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - TECHNISCHE UNIVERSITAET MUENCHEN - KAROLINSKA INSTITUTET - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA - ATDBIO LIMITED - - - EUR 3 979 632,96 - - - DNA-Based Modular Nanorobotics - - - EUR 3 979 632,96 - - - Denmark - Germany - Germany - Sweden - United Kingdom - Italy - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Robotic systems essentially comprise sensors and actuators connected to and coordinated by an information-processing unit. These principles apply to the human scale robotic systems that currently transform the way we work and - live. With DNA-Based Modular Robotics (DNABOT) we will take the first steps to scale advanced robotic behavior to the molecular scale for future medical and technological applications. DNABOT brings together the leading research groups in DNA - nanotechnology in Europe to collectively develop an integrated and modular robotic platform and demonstrate applications of the novel technology. DNA-based construction is a natural modular platform, which via the programmability of sequence design - and self-assembly allows different structural and functional motifs to be flexibly combined. DNA modules will be developed with a range of novel functions for sensing, actuation and intra-system communication and computing, implementing all of the - typical components required for a robotic system at the molecular level. Our overall goal is the creation of the first “industry standard” for modular robotics by the establishment of a modular “plug-and-play” platform that allows the construction of - custom-made nanorobots for advanced applications in research and industry. The ESRs will be trained in and develop functional modules that in close collaboration among the ESRs and Partners will be assembled to advanced molecular robots. The highly - interdisciplinary research and training program will exploit the synergy between the different competences of the Partners. The innovative and applied focus is supported by the involvement of the company ATDBio as Beneficiary and five companies as - Partner Organization that will also provide complementary skills training and intersectoral exposure of the ESRs. This proposal takes the first steps for future application of nanoscale robots in research and industry and will train future - generations of researchers in this field. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Denmark - - - DNABOT - - - H2020-MSCA-ITN-2017 - - - 765703 - - - - - UNIVERSITAET BIELEFELD - UNIVERSITETET I TROMSOE - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - GOETEBORGS UNIVERSITET - THE UNIVERSITY OF BIRMINGHAM - VRIJE UNIVERSITEIT BRUSSEL - LAVISION BIOTEC GMBH - CHERRY BIOTECH - ELVESYS SAS - - - EUR 3 728 513,16 - - - Super-resolution optical microscopy of nanosized pore dynamics in endothelial cells - - - EUR 3 728 513,16 - - - Germany - Norway - United Kingdom - Sweden - United Kingdom - Belgium - Germany - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - DeLIVER will train a new generation of ESRs in the development and application of newly developed high speed and high resolution imaging tools in biomedical research. ESRs will be cross-pollinated with concepts and skills in - physics and biomedicine, in particular in super-resolution optical imaging (a.k.a. optical nanoscopy), analytical image reconstruction, and optical micro-manipulation methods. These skills are applied to reveal for the first time the function and - dynamics of nanosized pores in endothelial cells (EC) that present the main barrier between the blood and vital organs for human physiology, such as the liver, brain, kidneys, and the eyes. Very little is known about the extremely important - physiological function of these unique structures and their role in the transfer and/or clearance of metabolites and pharmaceuticals to vital organs. The current generation of optical nanoscopes, however, is rather slow and can only be applied to - isolated, typically fixed (i.e. dead) cells rather than biomedically relevant tissues. Also, newcomers to the field need to familiarize themselves with a whole new set of potential problems that might arise in the use of optical nanoscopy, such as - image reconstruction-related artifacts to name just one example.This is an area of research where European enterprises are very active. Excellent training in new scientific and complementary skills, combined with international and intersectoral work - experience, will instil an innovative, creative and entrepreneurial mind-set in DeLIVER's ESRs, maximising economic benefits based on scientific discoveries. These specialised, highly trained, and mobile ESRs will have greatly enhanced career - prospects. The training in novel physical methods with highly relevant experience in the biomedical sciences will allow them to confidently navigate at the interface of academic, clinical and private sector research. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - DeLIVER - - - H2020-MSCA-ITN-2017 - - - 766181 - - - - - ACADEMISCH ZIEKENHUIS GRONINGEN - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - HELSINGIN YLIOPISTO - WEIZMANN INSTITUTE OF SCIENCE - UNIVERSITETET I OSLO - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - EBERHARD KARLS UNIVERSITAET TUEBINGEN - INSTITUTE OF CANCER RESEARCH - ROYAL CANCER HOSPITAL - KING'S COLLEGE LONDON - ANAXOMICS BIOTECH, S.L. - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - ADJUVATIS - QPS NETHERLANDS BV - UNIVERSITAETSKLINIKUM FREIBURG - - - EUR 3 890 064,96 - - - Driving next generation autophagy researchers towards translation - - - EUR 3 890 064,96 - - - Netherlands - France - Finland - Israel - Norway - Spain - Germany - United Kingdom - United Kingdom - Spain - Germany - France - Netherlands - Germany - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - The manipulation of autophagy has an enormous therapeutic potential to revolutionize the way we currently treat cancers, neurodegenerative disorders, inflammatory and infectious diseases. Despite the great promises made by - pioneering medical studies, the still limited applied research on autophagy has hampered the translation of fundamental knowledge into clinical-grade products and improved healthcare. Applied autophagy research is essential to understand the roles of - autophagy in the different physiological and pathological situations, to generate (disease) models and develop biomarkers and assays to assess its progress. - - 2021-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Netherlands - - - DRIVE - - - H2020-MSCA-ITN-2017 - - - 765912 - - - - - ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE - ISTITUTO NAZIONALE DI FISICA NUCLEARE - UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II. - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN - PANGEA FORMAZIONE SRL - LUNDS UNIVERSITET - UNIVERSITETET I OSLO - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH - THE UNIVERSITY OF EDINBURGH - - - EUR 3 026 260,26 - - - International Training Network for Statistics in High Energy Physics and Society - - - EUR 3 026 260,26 - - - United Kingdom - Italy - Italy - Germany - Netherlands - Italy - Sweden - Norway - Switzerland - United Kingdom - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - - The INSIGHTS Innovative Training Network will develop advanced statistical methods, implement them in software, and apply them to solve problems in Particle Physics and other fields. In doing so, we will create the next - generation of experts not only able to investigate Nature's fundamental particles but also to solve problems of broad relevance to society. The analysis of data collected in Particle Physics experiments such as those at the Large Hadron Collider - (LHC) poses tremendous challenges, and advanced statistical methods have proven to be key elements of recent advances in the field. INSIGHTS will enable significant further progress with particular emphasis on multivariate analysis, parametric - modelling and Bayesian computation. We will ensure that the statistical tools can cope with the complexities of real experimental settings by using them in actual analyses, such as searches for new fundamental particles at the LHC. In carrying out - the proposed research, INSIGHTS will train a cohort of physicists in modern statistical methods and establish collaborations and educational structures that will continue long into the future. In particular we plan to establish a new Pan-European - Advanced School of Statistics, which will take the training of EU researchers to a higher level. The participating institutes in INSIGHTS have a successful track record of and innovation and education in statistical data analysis, and their expertise - will form the core of the training provided. In addition, secondments with partners in other disciplines such as Finance, Climate Science and Volcanology will allow participants to view statistical and computational problems from multiple viewpoints - and to exchange ideas between these areas and Particle Physics. - - 2021-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - INSIGHTS - - - H2020-MSCA-ITN-2017 - - - 765710 - - - - - STICHTING VUMC - UNIVERSITAETSKLINIKUM HAMBURG-EPPENDORF - INSTITUT DE INVESTIGACIO EN CIENCIES DE LA SALUT GERMANS TRIAS I PUJOL - FUNDACAO D. ANNA SOMMER CHAMPALIMAUD E DR. CARLOS MONTEZ CHAMPALIMAUD - CENTRE HOSPITALIER UNIVERSITAIRE MONTPELLIER - PLOVDIVSKI UNIVERSITET PAISIY HILENDARSKI - UNIVERSIDAD DE GRANADA - PANGAEA BIOTECH SL - EXOSOMICS SIENA SPA - - - EUR 3 727 722,96 - - - European Liquid Biopsies Academy - Towards widespread clinical application of blood-based diagnostic tools - - - EUR 3 727 722,96 - - - Netherlands - Germany - Spain - Portugal - France - Bulgaria - Spain - Spain - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Liquid biopsies have been heralded as a game changer in cancer management, with blood tests offering a minimally invasive, safe, and sensitive alternative or complimentary approach for tissue biopsies. Blood represents a rich - source of information through which solid cancers (and their subtypes) can be detected, identified and classified, and matched to a specific therapy. However, despite the potential of individual approaches, the promise of liquid biopsies has not yet - materialised in the clinic. Widespread deployment requires creative next-generation researchers with an innovative mindset with access to a unique toolbox, including medical know-how, molecular diagnostics expertise (from health economics to - regulatory), and statistical/bioinformatical proficiency. Currently, there are no comprehensive training programmes to address this need. To move the promising liquid biopsy technology out of its infancy, the research programme and educational - curriculum of the European Liquid Biopsy Academy (ELBA) will cover the entire value chain of diagnostics development and integrate all required disciplines and sectors. - - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Netherlands - - - ELBA - - - H2020-MSCA-ITN-2017 - - - 765492 - - - - - HUMBOLDT-UNIVERSITAET ZU BERLIN - UNIVERSITAET BERN - UNIVERSITAT AUTONOMA DE BARCELONA - KOBENHAVNS UNIVERSITET - UNIVERSITAET KLAGENFURT - STICHTING VU - LEUPHANA UNIVERSITAT LUNEBURG - UNIVERSITE CATHOLIQUE DE LOUVAIN - THE FOREST TRUST LBG - UNILEVER U.K. CENTRAL RESOURCES LIMITED - - - EUR 3 895 103,16 - - - Operationalising telecouplings for solving sustainability challenges related to land use - - - EUR 3 895 103,16 - - - Germany - Switzerland - Spain - Denmark - Austria - Netherlands - Germany - Belgium - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Society depends on land for food, feed, fibre and energy, but the detrimental outcomes of unsustainable land practices are becoming increasingly apparent. Ensuring sustainable land use is a key challenge, yet hard to achieve - in today’s interconnected world where policies, consumer demands and environmental change in one region may affect far-away places. We face a significant knowledge gap regarding the processes related to land use that link distant places – or - telecouplings – and how these processes could be governed towards sustainability. Companies, institutions and policy makers lack the expertise and tools to ensure sustainable land use in a globalised world. COUPLED will educate researchers and - entrepreneurs in assessing and governing land use in a systemic way, accounting for the opportunities and threats arising from distal links between Europe and other regions. COUPLED builds on a strong interdisciplinary network to achieve its overall - objective of operationalising the novel telecouplings concept in order to support sustainable governance of land systems and related supply chains under global change. COUPLED will deliver on training a new generation of professionals and - entrepreneurs, developing rich analytic tools and new understandings to help private and public organisations to identify where and how they can intervene to make sustainable land use decisions, thereby avoiding unwanted outcomes. The consortiums - unites scientifically excellent partners across the natural and social sciences to ensure excellence in research, institutional and technological innovation. Working closely with large companies, SMEs, NGOs, international organisations and - administrative bodies, the ESRs will learn how to move between science and practice, become highly attractive to employers, and build successful careers in research, consulting, industry or governance. The action will thus contribute to Europe’s - leading position for a transformation towards sustainable land use. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - COUPLED - - - H2020-MSCA-ITN-2017 - - - 765408 - - - - - STICHTING KATHOLIEKE UNIVERSITEIT - SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI DI TRIESTE - UNIVERSITY COLLEGE LONDON - WEIZMANN INSTITUTE OF SCIENCE - NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - UNIVERSITE D'AIX MARSEILLE - Janssen Pharmaceutica NV - - - EUR 3 961 159,56 - - - Memory research: Ground-breaking, Applied, and Technological Exchanges - - - EUR 3 961 159,56 - - - Netherlands - Italy - United Kingdom - Israel - Norway - France - France - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - In M-GATE, ESRs will combine state-of-the art experimental neurophysiology, innovative technologies, and advanced theoretical approaches to unveil memory mechanisms, from single neurons to brain networks, to cognition and - behaviour, addressing the healthy and diseased brain. Through research and training from top-class scientists and close interaction with industrial partners, ESRs will develop unique multi-disciplinary skills combining physiology, molecular biology, - computation, micro-engineering, and entrepreneurship - - 2021-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Netherlands - - - M-GATE - - - H2020-MSCA-ITN-2017 - - - 765549 - - - - - CENTRO DE INVESTIGACION ECOLOGICA YAPLICACIONES FORESTALES CONSORCIO - Arizona Board of Regents - - - EUR 239 191,20 - - - Differential adaptation capacity of dryland grasses to directional changes in water availability (DIAGRASS). - - - EUR 239 191,20 - - - Spain - United States - - - Research Organisations - Higher or Secondary Education Establishments - - Understanding how the intensification of the water cycle, as projected by several climate models, will impact grassland ecosystems will be critical for evaluating their future capacity to provide services and for developing - sustainable management policies. This will be especially important in dryland regions, where water availability is the main driver of many ecological processes. To date, several studies have detected responses of vegetation to extreme events from - molecular to regional scales, although the heritability of these effects is still unclear. In addition, environmental stresses suffered by a generation can influence the phenotype and performance of its offspring beyond the effects of the transmitted - genes (the so-called transgenerational effect). Nevertheless, the description of the mechanisms involved in these responses is also incomplete. The lack of knowledge about the adaptation thresholds of species to new climate scenarios can hamper our - ability to predict shifts in ecosystem services. Therefore, the main objective of this project is to evaluate the adaptation capacity of dryland grass species to extreme scenarios of water availability. We will use short- and long-term rainfall - manipulative experiments combined with molecular (genomic, genetic and epigenetic), physiological, morphological and ecosystem approaches. The research outlined in this proposal includes a range of state-of-the-art methods to ensure the maximum - utility and impact of our results. Altogether, DIAGRASS aims to explore linkages from molecular to ecosystem processes to improve our ability to predict how more extreme rainfall regimes will affect future key ecosystem services (e.g., the - stocking-density capacity) of grasslands located in dryland regions. This project will also contribute to improve the knowledge in a key scientific topic for the EU: the Horizon 2020 societal challenge “Climate action, environment, resource - efficiency and raw materials”. - - 2021-03-31, Grant Agreement signed - - - 2018-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Spain - - - DIAGRASS - - - H2020-MSCA-IF-2016 - - - 746838 - - - - - KOBENHAVNS UNIVERSITET - WAGENINGEN UNIVERSITY - NAICONS SRL - THE UNIVERSITY OF WARWICK - OXFORD DRUG DESIGN LIMITED - LATVIJAS ORGANISKAS SINTEZES INSTITUTS - UNIVERSIDAD COMPLUTENSE DE MADRID - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - UNIVERSITEIT GENT - Statens Serum Institut - - - EUR 3 445 596,72 - - - Combatting Antimicrobial Resistance Training Network - - - EUR 3 445 596,72 - - - Denmark - Netherlands - Italy - United Kingdom - United Kingdom - Latvia - Spain - Spain - Belgium - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - - CARTNET trains young researchers in Europe to address serious and global problems of antibiotic resistance. Disease-causing bacteria are becoming resistant even to last resort antibiotics and transmission of resistance genes - and resistant pathogens is widespread between human, animal and environmental reservoirs. Therefore, CARTNET will focus on alternative approaches to handle antibiotic resistance and treating resistant infections in both humans and animals. It will - provide competences to young researchers and future policymakers that will allow them to use knowledge at all relevant scientific levels and in collaboration with stakeholders in both human and veterinary medicine as well as in chemistry, structural - biology and natural product chemistry to develop new antimicrobial solutions. CARTNET comprises researchers who are leading experts on antibiotic resistance and antimicrobial drug discovery. They will in cooperation with the recruited early stage - research (ESR) trainees use structural biology to synthesize new antimicrobials, screen environmental microorganisms and microbiota for new active compounds and limit spread of resistance through knowledge of dissemination of mobile genetic elements. - The research training is hosted by universities with a strong track record of graduate training and is composed of an ambitious scientific program flanked by essential generic training courses and with ample opportunity for networking at network - meetings, conferences and shared secondments. In addition to training young researchers for the challenges of tomorrow CARTNET will from day one provide excellent research with impressive scientific and societal impact. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Denmark - - - CARTNET - - - H2020-MSCA-ITN-2017 - - - 765147 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 359 688 - - - The challenging quest for low-mass dark structures - - - EUR 1 359 688 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Using strong gravitational lensing, I will constrain with my unique modelling technique and acquired knowledge the properties of dark matter and potentially revise the current standard paradigm for the formation of all - structures which is at the core of modern cosmology and galaxy formation theories. - - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - LEDA - - - ERC-2017-STG - - - 758853 - - - - - KUNGLIGA TEKNISKA HOEGSKOLAN - FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA) - UNIVERSIDAD DE VIGO - KING'S COLLEGE LONDON - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - Eidgenössische Technische Hochschule Zürich - INSTITUTE OF CANCER RESEARCH - ROYAL CANCER HOSPITAL - UNIWERSYTET WARSZAWSKI - - - EUR 3 863 978,28 - - - Computational ONcology TRaining Alliance - - - EUR 3 863 978,28 - - - Sweden - Spain - Spain - United Kingdom - United Kingdom - Switzerland - United Kingdom - Poland - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Cancer is a major cause of death and suffering, rendering it a huge concern to the general public. Consequently, it has been targeted by application of the molecular techniques developed during the last 20-25 years, thereby - improving diagnosis and treatment. Nevertheless, although current biomarker and treatment concepts often are successful initially, they subsequently frequently fail to achieve durable drug response and long-term survival for cancer patients. The - study of somatic evolution in cancer is a very promising approach to rectify this situation. Fortunately, single cell genomic sequencing has recently begun to provide opportunity to unprecedented detailed insights into tumour evolution and new - techniques are emerging for assaying the spatial distribution of tumour heterogeneity. Analysing and developing methods for these emerging data sets are under-researched areas that lie at the intersection of medical, evolutionary biology, and - computational research. In CONTRA, European researchers with complementary expertise have joined forces in order to collectively facilitate training of future European computational cancer researchers. We will by applying modern recruitment and - selection methods in combination with offering excellent training and employments conditions, including social security, facilitate recruitment of 15 excellent ESRs, across genders and geographical areas. We will train these 15 ESRs in the - mathematical, computational, and applied skills required to tackle the complex analysis problems posed by somatic evolution in cancer. We will also teach them entrepreneurship and the requirements of pharmaceutical and biotech industry. Using a novel - scheme, this substantial academic cancer expertise will be complemented with industrial expertise in software development, especially for biotech and pharmaceutical industry, which will unleash key components of the innovative force of the European - commercial sector in the struggle against cancer. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Sweden - - - CONTRA - - - H2020-MSCA-ITN-2017 - - - 766030 - - - - - KING'S COLLEGE LONDON - OSLO UNIVERSITETSSYKEHUS HF - FEOPS NV - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - UNIVERSITEIT MAASTRICHT - UNIVERSIDAD DE ZARAGOZA - UNIVERSITE DE BORDEAUX - CONSORCI INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER - GE VINGMED ULTRASOUND AS - MEDTRONIC BAKKEN RESEARCH CENTER B.V. - - - EUR 4 000 569,48 - - - Personalised In-Silico Cardiology - - - EUR 4 000 569,48 - - - United Kingdom - Norway - Belgium - United Kingdom - Netherlands - Spain - France - Spain - Norway - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Improving healthcare systems mandates a shift towards personalised and preventive management of disease. Specifically, the management of cardiovascular diseases has a huge impact on European society in terms of mortality, - morbidity and healthcare costs, being responsible for 1.9 million deaths in the EU annually (42% of all deaths) with a total cost of €169 billion. - - 2021-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - PIC - - - H2020-MSCA-ITN-2017 - - - 764738 - - - - - CENTRO DE INVESTIGACION ECOLOGICA YAPLICACIONES FORESTALES CONSORCIO - - - EUR 158 121,60 - - - Modelling Tree Response to Aridity Increase with Traits - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - The changes in precipitation patterns that are projected for the coming decades are expected to increase the frequency and intensity of droughts. Despite the potentially dramatic impacts on wood and forest-based ecosystem - services, the effect of these changes in the hydrological cycle on European forests is still highly uncertain. One reason for this gap in the knowledge is the inadequacy of the tools currently used to address large-scale land-atmosphere processes at - continental scales, the land surface models (LSMs). Indeed, the predictive power of LSMs is hampered by their heavy parameterization of empirical hydrological modules, with parameters fixed per broad plant type irrespective of the environmental - conditions. This representation is contradictory to the ecological processes of acclimation and selection and makes the LSMs unsuitable outside of their calibration range especially under extreme conditions. Ecologists have now made progress in - describing traits – tree characteristics that define plant growth strategies. Plant traits vary as much within species as between species, as individuals and communities adapt to their environmental conditions. - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - M-TRAIT - - - H2020-MSCA-IF-2016 - - - 747646 - - - - - AALTO-KORKEAKOULUSAATIO - AALTO-KORKEAKOULUSAATIO - - - EUR 1 411 258 - - - Novel Algorithmic Techniques through the Lens of Combinatorics - - - EUR 1 411 258 - - - Finland - Finland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Real-world optimization problems pose major challenges to algorithmic research. For instance, (i) many important problems are believed to be intractable (i.e. NP-hard) and (ii) with the growth of data size, modern applications - often require a decision making under {\em incomplete and dynamically changing input data}. After several decades of research, central problems in these domains have remained poorly understood (e.g. Is there an asymptotically most efficient binary - search trees?) Existing algorithmic techniques either reach their limitation or are inherently tailored to special cases. - - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Finland - - - ALGOCom - - - ERC-2017-STG - - - 759557 - - - - - UNIVERSITY OF LEEDS - UNIVERSITY OF HULL - UNIVERSIDADE DO MINHO - UNIVERSITETET I OSLO - JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN - HELSINGIN YLIOPISTO - EBERHARD KARLS UNIVERSITAET TUEBINGEN - LUNDS UNIVERSITET - INSTITUT PASTEUR - BIOMERIEUX SA - CENTITVC - CENTRO DE NANOTECNOLOGIA E MATERIAIS TECNICOS FUNCIONAIS E INTELIGENTES ASSOCIACAO - - - EUR 3 925 220,40 - - - VIral and BacteRial Adhesin Network Training - - - EUR 3 925 220,40 - - - United Kingdom - United Kingdom - Portugal - Norway - Germany - Finland - Germany - Sweden - France - France - Portugal - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - - ViBrANT (VIral and BacteRial Adhesin Network Training) brings together an interdisciplinary team of world-leading European infection researchers, focused on a cutting-edge translational research project to understand - host-pathogen adhesion and to develop novel, highly-specific nanoscale diagnostics to improve patient care. Host-pathogen interactions are the basis for infectious diseases, but the research methodologies needed to unravel these interactions and - translate them into viable diagnostic tools are complex and change rapidly. - - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - ViBrANT - - - H2020-MSCA-ITN-2017 - - - 765042 - - - - - MAX PLANCK INSTITUT FUER KOHLENFORSCHUNG - MAX PLANCK INSTITUT FUER KOHLENFORSCHUNG - - - EUR 1 485 000 - - - Shuttle Catalysis for Reversible Molecular Construction - - - EUR 1 485 000 - - - Germany - Germany - - - Research Organisations - Research Organisations - - Homogeneous catalysis is one of the pillars of modern chemical synthesis because it enables the sustainable preparation of molecules that find applications in medicinal chemistry, agrochemistry, and materials science. However, - many catalytic reactions use hazardous reagents, are unpractical on laboratory-scale or limited in scope. Moreover, while a relatively broad set of catalytic reactions are available to construct chemical bonds, methods to cleave those, which could - find applications in biomass and waste valorization, are rare. - - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - ShuttleCat - - - ERC-2017-STG - - - 757608 - - - - - LEUPHANA UNIVERSITAT LUNEBURG - - - EUR 159 460,80 - - - What Epistemology for Sustainability Science? Experiments and Theories for Social Transformation - - - EUR 159 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - Sustainability science is an innovative research field dealing with complex socio-ecological problems of our time, from climate change and rapid urbanization to pandemics and loss of biodiversity. A major goal for - sustainability science is to support societal transformations towards sustainability by generating, testing, and integrating (1) system knowledge about sustainability problems, (2) target knowledge about desirable futures, and (3) transformational - knowledge about effective interventions that can lead from the problems detected to the desirable futures. Thus far, epistemological work has focused primarily on the foundations of system and target knowledge and has neglected transformational - knowledge. Therefore, a major task for an epistemology of sustainability science is now to understand how transformational knowledge is generated and tested. Because of the central role they play in transformational sustainability science, in EPISUS, - I take transformational experiments as entrance point to develop an epistemology of transformational sustainability science. I ask: What kind of sustainability science do we need to generate and test transformational knowledge and what role can - transformational experiments play in this science? In EPISUS, I address this question by focusing on: 1. the main characteristics of transformational experiments, 2. the criteria used to evaluate experimental results and 3. the kind of theories that - support, or could support, the production of transformational knowledge. I use a research design that combines the investigation of concrete examples of transformational experiments and conceptual reflections using analytical tools from the - philosophy of science. EPISUS will provide a new conceptualization of transformational experiments as well as categories for the further development of transformational approaches in sustainability science that are theoretically sound and - evidence-based. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Germany - - - EPISUS - - - H2020-MSCA-IF-2016 - - - 752135 - - - - - FREIE UNIVERSITAET BERLIN - FREIE UNIVERSITAET BERLIN - - - EUR 1 491 487 - - - Neural mechanism underlying vocal interactions in duetting nightingales - - - EUR 1 491 487 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Humans and many animals produce complex vocal sequences in order to communicate with each other. What are the neuronal mechanisms that integrate the auditory information and permit the production of a coordinated motor - response during a vocal interaction? I will address this issue in the nightingale, a songbird species that is capable of duetting with rivals. During vocal interactions, nightingales have to precisely alternate between singing and listening, and I - will test whether premotor centers are differentially sensitive to auditory input during these two states. In zebra finches, I have shown that the impact of a father’s song on premotor circuitry can be regulated by inhibitory interneurons during - developmental song learning. Here I ask whether this same regulation of auditory input can rapidly change to support real-time vocal coordination in a duetting songbird. - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - MIDNIGHT - - - ERC-2017-STG - - - 757459 - - - - - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - - - EUR 195 454,80 - - - Coexistence on the boundary of chaos - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - This project is an exploration of the essence of chaos. Chaos and chaotic systems are by their very nature unpredictable. Paradoxically, the manner in which systems transition into chaotic regimes is highly structured and - rigid. This contradiction can be explained mathematically through an elegant process called renormalization. Renormalization is like a microscope which can be used to observe the shape of fractals that appear on the boundary of chaos. One aspect of - the structure of chaos is that such fractals on a large scale may look nothing like each other, but as the magnification factor on the microscope is increased they look more and more alike. This is expressed by saying that renormalization converges. - Convergence of renormalization has been a consistent theme since the very inception of chaos theory, thus it was believed that the structure of chaos was thoroughly understood. In an unexpected twist, the applicant recently made the groundbreaking - discovery that there are natural systems for which the renormalization sometimes is convergent and at other times degenerate. This reveals that the structure of chaos in fact is much more intricate than was previously imagined. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - COEXIST - - - H2020-MSCA-IF-2016 - - - 743959 - - - - - FORSCHUNGSZENTRUM JULICH GMBH - FORSCHUNGSZENTRUM JULICH GMBH - - - EUR 1 498 125 - - - Light-controlled synthetic enzyme cascades - - - EUR 1 498 125 - - - Germany - Germany - - - Research Organisations - Research Organisations - - There is an urgent need for the development of greener syntheses procedures if mankind wants to maintain an environment worth living in but is at the same time unwilling to accept a reduction in material comfort. The - establishment of more biocatalytic steps in chemical syntheses is one possible solution, as enzymes and whole cells offer sustainable advantages, such as biodegradability, intoxicity, high selectivity, and many more. As a myriad of enzymatic - reactions exist for almost any product, their potential is immense. Great scientific achievements and new techniques recently developed have enabled the design of economically and ecologically feasible multi-step enzyme cascades. However, with these - new opportunities, also new challenges arise. The more enzyme steps are combined in one pot, the higher the risk of undesired cross-reactivity is. There is thus an urgent need for a tight control of each biocatalytic step in a cascade in order to - obtain the desired product in a high purity and to make use of all advantages that enzyme cascades intrinsically offer. With LightCas, I aim to break new grounds in the area of multi-step (bio)catalysis by enabling an orthogonal, selective and thus - flexible on/off tuning of enzymes in a cascade. By entrapping enzymes into light-switchable microgels, using photo-switchable active site lids and light-induced enzyme deactivation, three methods providing the opportunity to control enzyme activity - in vitro and in vivo on demand will be (further) developed. The ultimate goal is to set up a one-pot multi-step light-controlled enzyme reactor yielding the desired product in high selectivity and concentration in a technically self-regulated manner. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - LightCas - - - ERC-2017-STG - - - 757320 - - - - - ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM - ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM - - - EUR 149 938 - - - ErasmusBlink: A low cost and easy to use measurement system for medical research with diagnostic potential - - - EUR 149 938 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Neuroscientists and clinicians use a wide range of behavioral tests to investigate the physiological mechanisms of learning and memory formation. One of the most objective and reliable tests is eyeblink conditioning, as it is - extremely simple, it can be done in both humans and animals, it measures many aspects of how we learn in our daily life, and it can detect memory deficits in many neurological and psychiatric diseases. However, so far there are no low-cost reliable - eyeblink conditioning setups commercially available. Therefore, we propose for this ERC-POC application to prepare the commercialization of ErasmusBlink as a low-cost, wearable eyeblink conditioning recording and analysis setup that can be used in - virtually all species. With ErasmusBlink one can do reliable and reproducible eyeblink conditioning experiments for scientific, medical and industrial purposes. ErasmusBlink will be the first ‘total care’ package, alleviating the potential customer - from the requirement of the technical and programming skills, which one currently needs to acquire before being able to do eyeblink conditioning experiments. Our market survey will cover three major fields: Basic neurosciences (1), clinical and - pharmaceutical research (2), and nutritional sciences (3). For all three fields eyeblink conditioning parameters have been shown to uncover important and fundamental functional processes and correlations. Our current academic collaborations with key - players in each of these disciplines and with industrial partners like Noldus IT serve as a solid platform to ensure a successful commercialization of ErasmusBlink. - - 2018-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Netherlands - - - ErasmusBlink - - - ERC-2016-PoC - - - 737619 - - - - - LUONNONVARAKESKUS - LUONNONVARAKESKUS - - - EUR 1 814 610 - - - Towards Understanding the Impact of Climate Change on Eurasian Boreal Forests: a Novel Stable Isotope Approach - - - EUR 1 814 610 - - - Finland - Finland - - - Research Organisations - Research Organisations - - The vast boreal forests play a critical role in the carbon cycle. As a consequence of increasing temperature and atmospheric CO2, forest growth and subsequently carbon sequestration may be strongly affected. It is thus crucial - to understand and predict the consequences of climate change on these ecosystems. Stable isotope analysis of tree rings represents a versatile archive where the effects of environmental changes are recorded. The main goal of the project is to obtain - a better understanding of δ13C and δ18O in tree rings that can be used to infer the response of forests to climate change. The goal is achieved by a detailed analysis of the incorporation and fractionation of isotopes in trees using four novel - methods: (1) We will measure compound-specific δ13C and δ18O of leaf sugars and (2) combine these with intra-annual δ13C and δ18O analysis of tree rings. The approaches are enabled by methodological developments made by me and ISOBOREAL collaborators - (Rinne et al. 2012, Lehmann et al. 2016, Loader et al. in prep.). Our aim is to determine δ13C and δ18O dynamics of individual sugars in response to climatic and physiological factors, and to define how these signals are altered before being stored - in tree rings. The improved mechanistic understanding will be applied on tree ring isotope chronologies to infer the response of the studied forests to climate change. (3) The fact that δ18O in tree rings is a mixture of source and leaf water signals - is a major problem for its application on climate studies. To solve this we aim to separate the two signals using position-specific δ18O analysis on tree ring cellulose for the first time, which we will achieve by developing novel methods. (4) We - will for the first time link the climate signal both in leaf sugars and annual rings with measured ecosystem exchange of greenhouse gases CO2 and H2O using eddy-covariance techniques. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Finland - - - ISOBOREAL - - - ERC-2017-STG - - - 755865 - - - - - UNIVERSITAT LINZ - UNIVERSITAT LINZ - - - EUR 1 499 975 - - - Smart HydroGEL SYStems – From Bioinspired Design to Soft Electronics and Machines - - - EUR 1 499 975 - - - Austria - Austria - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Hydrogels evolved as versatile building blocks of life – we all are in essence gel-embodied soft machines. Drawing inspiration from the diversity found in living creatures, GEL-SYS will develop a set of concepts, materials - approaches and design rules for wide ranging classes of soft, hydrogel-based electronic, ionic and photonic devices in three core aims. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Austria - - - GEL-SYS - - - ERC-2017-STG - - - 757931 - - - - - STICHTING KATHOLIEKE UNIVERSITEIT BRABANT - STICHTING KATHOLIEKE UNIVERSITEIT BRABANT - - - EUR 1 999 676 - - - The Resilience and Evolution of Economic Activism and the Role of Law - - - EUR 1 999 676 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The global financial crisis put basic tenets of neoliberalism into question. Previous crises on product safety also exemplified the limits of delegating regulatory power. However, in the medium run, private regulatory bodies - re-assume their previous powerful status and continue to exert undue influence on the functioning of economic activity. - - 2022-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - REVEAL - - - ERC-2016-COG - - - 725798 - - - - - KOBENHAVNS UNIVERSITET - KOBENHAVNS UNIVERSITET - - - EUR 149 986 - - - GPCR Exploitation To Unlock the Power of Brown/Beige Adipose Tissue - - - EUR 149 986 - - - Denmark - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Hundreds of millions of people suffer from obesity and diabetes worldwide. These diseases diminish both life quality and expectancy and new treatment strategies are desperately needed. One possible approach is to target the - calorie-burning and glucose-consuming functions of brown and beige adipose tissue (B/BAT). Previous attempts to harness the therapeutic potential of B/BAT have largely focused on the β-adrenergic class of G protein-coupled receptors (GCPRs). - Unfortunately, these methods are hindered by adverse cardiovascular side effects linked to adrenergic activation. Therefore, uncovering non-adrenergic alternatives to exploit B/BAT for treating metabolic disease holds the potential for enormous - societal and economic benefit. - - 2018-08-31, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Denmark - - - GET-UP BAT - - - ERC-2017-PoC - - - 768783 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 183 454,80 - - - The Socialization of Private Sector Elites in Kenya - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - SOPRISEKEN focuses on the sociability of professional and managerial elites in modern Kenya. Studying socialization, and in particular the membership organizations in which it takes place, is a particularly fruitful way to - understand how these elites have experienced the social and economic changes triggered in Africa by the “structural adjustment” policies of the 1980s; how they have come to understand themselves as a distinct social group - the “private sector” - - sharing comparable social aspirations, lifestyle and economic ethos; and how the articulation of their interests has led to the development of similar civic and political attitudes. - - 2019-04-30, Grant Agreement terminated - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SOPRISEKEN - - - H2020-MSCA-IF-2016 - - - 749372 - - - - - UNIVERSITE GRENOBLE ALPES - - - EUR 173 076 - - - The origin of the IMF through multi-scale analysis of molecular clouds: unification of PDF and power spectrum analysis - - - EUR 173 076 - - - France - - - Higher or Secondary Education Establishments - - The omnipresence of filamentary structures inside nearby molecular clouds observed by the Herschel space observatory challenges our comprehension of the star formation process. We now know that most of the cold dense cores - appear to form within those filaments, which suggest a possible link between the characterisation of the filamentary structure of molecular clouds and the core mass function (CMF). Physical processes such as turbulence, gravitational fragmentation - and the influence of magnetic field transform the interstellar medium and leave characteristic signatures within the shape of structures. In order to understand the physical processes leading to the formation of filaments and cores in molecular - clouds and later to the formation of stars, many statistical tools have been developed to characterise such signatures. Among them there are the probability distribution function (PDF), which form the foundation of many modern theories of star - formation, and the power spectrum analysis, which started with the pioneer work of Andrey Kolmogorov and remains our best tool today to analyse and characterise the turbulence. Usually measured independently, I propose in this project to unify both - analysis through a multi-scale analysis approach of nearby molecular clouds. In the recent years, I developed wavelet based analysing techniques allowing me to separate the different statistical signatures of physical processes involved in filaments - and cores formation. Furthermore, part of these techniques also imply the analysis of linear polarisation allowing a unique multi-scale description of the interstellar magnetic field. The aim of this project is to build a global and coherent picture, - based on observations, of how cloud structures and magnetic fields have an impact on the formation of dense cores. - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - Filaments to stars - - - H2020-MSCA-IF-2016 - - - 750920 - - - - - VYSOKE UCENI TECHNICKE V BRNE - UNIVERSITAET STUTTGART - Asociacion - Centro de Investigacion Cooperativa en Nanociencias - CIC NANOGUNE - THOMAS KEATING LIMITED - - - EUR 2 898 683,75 - - - Plasmon Enhanced Terahertz Electron Paramagnetic Resonance - - - EUR 2 898 683,75 - - - Czech Republic - Germany - Spain - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - We propose to establish Plasmon-enhanced Terahertz Electron Paramagnetic Resonance spectroscopy and scanning microscopy as a unique Electron Paramagnetic Resonance (EPR) platform for high-sensitivity local analysis of - paramagnetic organic and inorganic species and materials. Here, we will deliver novel hardware and infrastructure providing ground-breaking innovation in the magnetic sensing and imaging. The platform is conceptually based on incorporating THz - plasmonic antennas onto surfaces (spectroscopy) and scanning probe tips (microscopy), resulting in a strong, local enhancement (about two orders of magnitude) of the magnetic sensing field. - - - 2020-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-01-2016-2017 - FET-Open research and innovation actions - - - RIA - Research and Innovation action - - - Czech Republic - - - PETER - - - H2020-FETOPEN-1-2016-2017 - - - 767227 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 998 250 - - - Brain computer interface to study and manipulate mamories of aversive experience during sleep - - - EUR 1 998 250 - - - France - France - - - Research Organisations - Research Organisations - - The aim of this project is to study the influence of sleep in the establishment of aversive memory and to propose a proof of concept for the use of brain-computer interfaces during sleep to treat pathologies associated with - fear or anxiety such as post-traumatic stress disorders. - - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - France - - - MNEMOSYNE - - - ERC-2016-COG - - - 726169 - - - - - THE UNIVERSITY OF READING - UNIVERSITAT KONSTANZ - UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA - UNIWERSYTET JAGIELLONSKI - UNIVERSIDAD POMPEU FABRA - UNIVERSITEIT LEIDEN - ARISTOTELIO PANEPISTIMIO THESSALONIKIS - UNIVERSITI PUTRA MALAYSIA - UNIVERSITE DE GENEVE - IRCCS - ASSOCIAZIONE LA NOSTRA FAMIGLIA 'ISTITUTO SCIENTIFICO EUGENIO MEDEA' - CENTRO PROVINCIALE PER L'ISTRUZIONEDEGLI ADULTI PALERMO 1 - - - EUR 3 778 888,68 - - - The Multilingual Mind - - - EUR 3 778 888,68 - - - United Kingdom - Germany - Italy - Poland - Spain - Netherlands - Greece - Malaysia - Switzerland - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - - The aim of the project ‘MultiMind’ is to establish an international, multidisciplinary and multisectorial training network on multilingualism. Given the current migration and refugee crisis in Europe, there is an urgent need - to provide an in depth investigation of multilingualism from a multidisciplinary perspective that will bridge the gap between fundamental and applied research and will addresses societal challenges within the education and health sector as well as - challenges related to the education of migrants and refugees in Europe. MultiMind addresses the benefits and challenges of multilingualism through an innovative research programme that combines fundamental and applied research across disciplines in a - range of different social and educational settings. It investigates the influence of multilingualism on language learning, cognition, creativity, and decision making, on brain function and structure, and its role as a reserve in atypical populations - using a combination of cutting edge research methodologies. MultiMind is composed of 9 academic and 2 non-academic organisations as well as 16 partners in leading academic institutions, companies, health organisations and 5 branches of Bilingualism - Matters, a leading international network of centres that provide outreach activities on multilingualism. The consortium brings together researchers with complementary expertise within the disciplines of linguistics, psychology, education, - neuroscience, and speech & language therapy along with non-academic partners within the education and health sectors, IT and publishing. This will enable to address societal challenges within education and health as well as challenges related to - the migration and refugee crisis in Europe whilst training a new generation of researchers in world-leading labs using cutting edge methodologies and allowing them to build the necessary skills fostering their career progress as independent - researchers in academic or nonacademic sectors. - - 2022-03-31, Grant Agreement signed - - - 2018-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - MultiMind - - - H2020-MSCA-ITN-2017 - - - 765556 - - - - - ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON - THE UNIVERSITY OF MANCHESTER - SCHWEIZERISCHES FORSCHUNGSINSTITUT FUER HOCHGEBIRGSKLIMA UND MEDIZIN IN DAVOS - IDRYMA IATROVIOLOGIKON EREUNON AKADEMIAS ATHINON - UNIVERSYTET MEDYCZNY W LODZI. - UMEA UNIVERSITET - GIORGI ELIAVA INSTITUTE OF BACTERIOPHAGY, MICROBIOLOGY AND VIROLOGY - ELIAVA BIO PREPARATIONS LTD - EUROPEAN FEDERATION OF ASTHMA &ALLERGY ASSOCIATIONS IDEELL FORENING - MARIOS LYMARAKIS KAI SIA EE - - - EUR 2 971 750 - - - Constructing a ‘Eubiosis Reinstatement Therapy’ for Asthma - - - EUR 2 971 750 - - - Greece - United Kingdom - Switzerland - Greece - Poland - Sweden - Georgia - Georgia - Belgium - Greece - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The asthma pandemic imposes a huge burden on patients and health systems in both developed and developing countries. Notwithstanding major efforts in untangling its pathophysiology, we are not even close to reaching a cure. - Despite available treatments, symptom control is generally suboptimal and hospitalisations and deaths remain at unacceptably high levels. This calls for disruptive innovation towards a long-term treatment strategy. Asthma is an inflammatory condition - associated with immune deviations, most often atopic allergy. However, a key characteristic of asthma that remains relatively unexplored is susceptibility to infection. Most acute asthma attacks follow upper respiratory infections; infections are - also associated with asthma initiation and persistence. Recent studies reveal that the respiratory microbiome is characteristically imbalanced (dysbiotic) in asthma. Our own data indicate that a feature of dysbiosis in asthma is reduced abundance of - bacteriophages (phages). These bacterial viruses infect and are able to naturally control bacterial populations. Phage therapy has been grossly neglected in the western world and is currently just appearing as a novel tool against infection. However, - it has never been used for rebalancing dysbiosis in humans. - - 2021-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-01-2016-2017 - FET-Open research and innovation actions - - - RIA - Research and Innovation action - - - Greece - - - CURE - - - H2020-FETOPEN-1-2016-2017 - - - 767015 - - - - - ECOLE CENTRALE DE MARSEILLE - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - UNIVERSITY OF NORTHUMBRIA AT NEWCASTLE - CESKE VYSOKE UCENI TECHNICKE V PRAZE - UNIVERSIDAD DE LAS PALMAS DE GRAN CANARIA - OZYEGIN UNIVERSITESI - INSTITUTO DE TELECOMUNICACOES - OSRAM GMBH - INDRA SISTEMAS SA - OLEDCOMM SAS - FORD OTOMOTIV SANAYI ANONIM SIRKETI - - - EUR 3 752 913,96 - - - European Training Network on Visible light based Interoperability and Networking - - - EUR 3 752 913,96 - - - France - Germany - United Kingdom - Czech Republic - Spain - Turkey - Portugal - Germany - Spain - France - Turkey - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Jiri Matas - Tel.: +420 22435721 - Fax: +420 224357385 - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - New generations of LEDs have attractive features such as a long life expectancy, lower power consumption and reduced heat dissipation. In line with governmental plans worldwide, it is predicted that LEDs will be the ultimate - light source in the near future. Besides indoor illumination, LEDs are being widely used in street lighting, traffic signs, advertising displays, transportation, etc. Visible light communication (VLC) is one of the most promising current areas of - research with a significant potential for high-impact results, and successful outcomes might revolutionize utilization of LEDs for modern infrastructures to add novel functionalities in addition to illumination. VLC has been proposed for smart homes - and streets, manufacturing and medical environments for increased data security and reduced interference, or a two-way vehicle-to-vehicle and vehicle-to-roadside infrastructure communications as part of the emerging intelligent transportation systems - for increasing road safety. The proposed “European Training Network on Visible-light based Interoperability and Networking (VisIon)” aims to train a new generation of early-stage researchers (ESRs) in the emerging area of VLC. Through research on - co-supervised individual projects focusing on selected applications, VisIon will make significant contributions to the fundamental scientific understanding and technical knowhow. Targeted application areas include indoor and outdoor VLC access, smart - transportation, and medical and manufacturing environments. In addition to technical training through PhD courses, dedicated tutorials and workshops organized by the Network, the ESRs will benefit from a wide range of complementary non-technical - training activities such as entrepreneurship, authoring scientific papers/patents, dissemination, etc. The participation of industrial partners will further promote research training with commercialisation perspectives enabling ESRs to fully - integrate theory with hands-on practice. - - 2021-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - France - - - VisIoN - - - H2020-MSCA-ITN-2017 - - - 764461 - - - - - Academisch Medisch Centrum bij de Universiteit van Amsterdam - STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN - SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO SANT'ANNA - TECHNISCHE UNIVERSITEIT EINDHOVEN - DUALIS MEDTECH GMBH - XELTIS BV - - - EUR 3 035 550 - - - Development of the first fully biocompatible, soft actuated heart: combining in situ tissue engineering and soft robotics - - - EUR 3 035 550 - - - Netherlands - Netherlands - Italy - Netherlands - Germany - Netherlands - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The Hybrid Heart consortium envisions to develop and bring to the clinic soft biocompatible artificial organs. These will consist of a soft robotics shell with actuators (‘artificial muscles’) and sensors, enabling completely - natural motion. The inner lining and structures will be made by in situ tissue engineering (TE), ensuring biocompatibility of blood-contacting surfaces. - - 2022-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-01-2016-2017 - FET-Open research and innovation actions - - - RIA - Research and Innovation action - - - Netherlands - - - HybridHeart - - - H2020-FETOPEN-1-2016-2017 - - - 767195 - - - - - ASSOCIACAO DO INSTITUTO SUPERIOR TECNICO PARA A INVESTIGACAO E DESENVOLVIMENTO - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - INSTITUT JOZEF STEFAN - CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL - SOFIISKI UNIVERSITET SVETI KLIMENT OHRIDSKI - CHARGE2C-NEWCAP LDA - - - EUR 3 764 276,25 - - - Plasma Enabled and Graphene Allowed Synthesis of Unique nano Structures - - - EUR 3 999 633,75 - - - Portugal - France - Slovenia - Germany - Bulgaria - Portugal - - - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - "PEGASUS ultimate goal is to create a highly efficient, catalyst/harmful-free novel plasma method along with a proof-of-concept PEGASUS device for a large-scale N-graphene direct synthesis, as well as - N-graphene/MnO2/Fe2O3/SnO2 composites and unique vertical N-graphene arrays grown on metal substrates, via breakthrough research on plasma-enabled singular assembly pathways. By doing so, a disruptive and highly competitive alternative to - conventional lengthy/multistep routes will emerge, based on the mastering of plasma exclusive mechanisms to control the amount and localization of energy and matter at atomic scales, spurring a new European manufacturing/processing platform. The - envisioned path will prompt and build on ground-breaking developments in the underlying physics, with the resulting processes embodying invaluable economic/social impact potential. PEGASUS framework is uniquely positioned to succeed and raise the - Europe competitiveness in the strategic nano synthesis domain via the promotion of plasma methods as a Key Enabling Technology for highly controllable and ""green"" assembly of atom-thick hybrid nanostructures and by replacing long existing materials - with new cost-effective, higher performance ones. The synergy between plasma physics and mechanical, electrochemical and hi-tech engineering expertise will be the driving force boosting the innovative approach pursued by this project, spanning from - fundamental knowledge to appliance prospects. Internationally recognized scientists will contribute to this interdisciplinary project, triggering the commercialization of novel materials and delivering proof-of-concept PEGASUS and supercapacitor - devices. With a science-devoted team lead by a female coordinator, PEGASUS contribution ambitions go beyond the scientific scope, helping to bridge economical/social gaps in tune with the EU ambitions." - - 2021-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-01-2016-2017 - FET-Open research and innovation actions - - - RIA - Research and Innovation action - - - Portugal - - - PEGASUS - - - H2020-FETOPEN-1-2016-2017 - - - 766894 - - - - - UNIVERSITAETSKLINIKUM HAMBURG-EPPENDORF - EBERHARD KARLS UNIVERSITAET TUEBINGEN - KUNGLIGA TEKNISKA HOEGSKOLAN - ACADEMISCH ZIEKENHUIS LEIDEN - SYDDANSK UNIVERSITET - LUDGER LTD - RIJKSUNIVERSITEIT GRONINGEN - UNIVERSITETET I OSLO - UNIVERSITAET FUER BODENKULTUR WIEN - ALPHALYSE A/S - HEXAL AKTIENGESELLSCHAFT - - - EUR 3 933 617,40 - - - Analytics for Biologics - - - EUR 3 933 617,40 - - - Germany - Germany - Sweden - Netherlands - Denmark - United Kingdom - Netherlands - Norway - Austria - Denmark - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Qualitative and quantitative analysis and purification of therapeutic protein species (TP-S) – coded by the same gene, thus chemically often very similar – is one of the most challenging problems in analytical chemistry today. - This problem is of huge impact in the area of therapeutic proteins (TPs) – a rapidly growing market – causing a high demand in specialists in the field of TP manufacturing. This demand can currently not be met by single European universities. In an - Europe-wide joint research and training network the graduate school A4B will offer a specific training program yielding the required specialists. A4B-PhD students will develop solutions for the most urgent problems in TP production and analysis. - - - 2021-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - A4B - - - H2020-MSCA-ITN-2017 - - - 765502 - - - - - KOBENHAVNS UNIVERSITET - KOBENHAVNS UNIVERSITET - - - EUR 1 761 190 - - - How do infants mentalize? Bringing a neuroimaging approach to the puzzle of early mindreading. - - - EUR 1 761 190 - - - Denmark - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Human social interaction and learning depends on making the right inferences about other people’s thoughts, a process commonly called mentalizing, or Theory of Mind, a cognitive achievement which several decades of research - concluded was reached at around age 4. The last 10 years has radically changed this view, and innovative new paradigms suggest that even preverbal infants can think about others’ minds. This new developmental data has created arguably one of the - biggest puzzles in the history of developmental science: How can infants be mentalizing when years of research have shown that a) pre-schoolers fail at mentalizing tasks and b) mentalizing depends on the development of cognitive control, language, - and brain maturation? The key issue is whether behaviour that looks like infant mentalizing really is mentalizing, or might infants’ success belie alternative processes? The most powerful strategy for resolving this puzzle is to look to brain - activity. By applying the same methods and paradigms across infancy and early childhood, DEVOMIND will investigate whether infants’ success on mentalizing tasks recruits the same network of brain regions, and neural processes, that we know are - involved in success in older children and adults. In the second half of the project, we will use our neural indicators of mentalizing to test a completely novel hypothesis in which infants’ success is possible because they have a limited ability to - distinguish self from other. Although novel, this hypothesis deserves to be tested because it has the potential to explain both infants’ success and preschoolers’ failures under a single, unified theory. By bringing a neuroimaging approach to the - puzzle of early mentalizing, DEVOMIND will allow us to move beyond the current impasse, and to generate a new theory of Theory of Mind. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Denmark - - - DEVOMIND - - - ERC-2016-COG - - - 726114 - - - - - CONSIGLIO NAZIONALE DELLE RICERCHE - FORSCHUNGSZENTRUM JULICH GMBH - FEI ELECTRON OPTICS BV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - UNIVERSITY OF GLASGOW - QED FILM & STAGE PRODUCTIONS LTD - UNIVERSITA DEGLI STUDI DI MODENA E REGGIO EMILIA - UNIVERSITEIT MAASTRICHT - - - EUR 2 997 675 - - - QUANTUM SORTER - - - EUR 2 997 675 - - - Italy - Germany - Netherlands - Germany - United Kingdom - United Kingdom - Italy - Netherlands - - - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Q-SORT introduces a revolutionary concept whereby the TEM is employed as a Quantum Sorter. All TEM techniques are in fact limited to the imaging and energy spectroscopy of the electron wavefunction. Moreover, when a single - sample property is sought, most of the image information is useless, a waste that cannot be afforded in dose-sensitive materials. The Quantum Sorter leverages the recently-acquired capacity to structure e-beams, which implies that if, in a quantum - experiment (tunable state preparation, interaction, analysis), the analysis is performed over the ‘optimal’ basis of quantum states, very few electrons are necessary for the full characterisation of a sought property, i.e. the TEM can be tuned to - answer a single question but with maximum efficiency. To this end, Q-SORT introduces a new parallel analysis strategy, based on a suitable conformal mapping of the wavefunction: the starting point is the analysis of orbital angular momentum (OAM), - but building a recipe for diagonalising a wider range of observables is one of the planned Breakthroughs of Q-SORT. This will in turn allow Q-SORT to achieve three other high-risk Breakthroughs of vast applicability: assessing the OAM of plasmonic - resonances in select nanoparticles, achieving atomic-resolution magnetic dichroism, identifying different proteins based on selected properties. We believe that the Quantum Sorter will become so important that it will eventually be part of every - state-of-the-art TEM, since the new technology is easy to integrate with energy-loss spectrometry. The project consortium includes some of the world leaders in optical and electronic vortex beams, as well as in protein cryoTEM. A major industrial - partner in TEM is included, so as to secure market penetration of technological outcomes. The project avails itself of established resource and IPR management techniques. Gender balance and equal opportunities will be ensured. A comprehensive - outreach and dissemination strategy is foreseen. - - 2021-03-31, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-01-2016-2017 - FET-Open research and innovation actions - - - RIA - Research and Innovation action - - - Italy - - - Q-SORT - - - H2020-FETOPEN-1-2016-2017 - - - 766970 - - - - - Academisch Medisch Centrum bij de Universiteit van Amsterdam - INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE - KAROLINSKA INSTITUTET - THE BABRAHAM INSTITUTE - IFOM FONDAZIONE ISTITUTO FIRC DI ONCOLOGIA MOLECOLARE - ANAXOMICS BIOTECH, S.L. - Redoxis AB - HELMHOLTZ-ZENTRUM FUER INFEKTIONSFORSCHUNG GMBH - IBM RESEARCH GMBH - ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS - - - EUR 3 605 245,20 - - - COmbatting disorders of adaptive immunity with Systems MedICine - - - EUR 3 605 245,20 - - - Netherlands - France - Sweden - United Kingdom - Italy - Spain - Sweden - Germany - Switzerland - Greece - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - - Background: EU countries face large health challenges to combat chronic diseases. Recently, systems medicine has emerged as a promising discipline to accelerate the translation of basic research into applications for improved - diagnostics and personalized treatment. Its power arises from the integration of laboratory and computational approaches crossing research disciplines and sectors to solve clinical questions. COSMIC delivers the next generation of leading, - entrepreneurial, and innovative systems medicine professionals having expertise, skills, and experience to successfully combat complex human disorders. These professional will find excellent career opportunities. COSMIC focuses on B-cell neoplasia - and rheumatoid arthritis, prototypical diseases originating from abnormal functioning of immune cells, often resulting in similar antigen specificities. COSMIC enables Early Stage Researchers to play a leading role in this exciting field. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Netherlands - - - COSMIC - - - H2020-MSCA-ITN-2017 - - - 765158 - - - - - QUEEN MARY UNIVERSITY OF LONDON - CENTRO DE NEUROCIENCIAS E BIOLOGIACELULAR ASSOCIACAO - UNIVERSITE D'ARTOIS - KAROLINSKA INSTITUTET - CENTRO HOSPITALAR E UNIVERSITARIO DE COIMBRA E.P.E. - HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH - MJR PHARMJET GMBH - UNIVERSITAET INNSBRUCK - THE UNIVERSITY OF WARWICK - - - EUR 3 590 354,52 - - - New nanomaterials for neural stem cells drug delivery - - - EUR 3 590 354,52 - - - United Kingdom - Portugal - France - Sweden - Portugal - Germany - Germany - Austria - United Kingdom - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Brain conditions such as neurodegenerative diseases, stroke and traumatic injuries are a mayor burden in modern society. Because neural stem cells (NSCs) can differentiate into new neural cells including neurons, the - regulation of their proliferation, differentiation and migration represent a promising regenerative/therapeutic strategy. The hypothesis of NanoStem project is that novel nanoparticles (NPs) combined with recent identified/developed pharmaceuticals - can be an efficient approach to control the biological activity of NSCs. The scientific project is organized in three work packages (WP), each focusing on specific objectives and containing well-defined deliverables. WP1 will focus on the synthesis - of the nanomaterials and the uploading of the therapeutics. WP2 will take the best nanoparticles and focus more on the evaluation of the permeation and efficacy of the formulations against NSCs. WP3 will focus on in vivo studies to evaluate the - formulations developed to tackle the brain and to assess their toxicity. The project will train 14 ESRs in areas including organic and polymer chemistry, cell biology, pharmacology, neuroscience, nanobiotechnology and clinical sciences. The project - will also provide a substantial training program in complementary skills, targeting both professional and personal development, and translation of research and entrepreneurship. The project brings together six academic partners, one hospital and two - industrial teams as full partners, complemented by four associate partners, one of which is an industrial team, distributed over a total of seven European Union member states. The consortium brings together groups with a very interdisciplinary - expertise ranging from nanoparticle synthesis and characterization, computational modeling, in vitro BBB models and BBB transport, neural stem cells, animal testing and clinical expertise. - - 2022-05-31, Grant Agreement signed - - - 2018-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - NANOSTEM - - - H2020-MSCA-ITN-2017 - - - 764958 - - - - - AARHUS UNIVERSITET - KATHOLIEKE UNIVERSITEIT LEUVEN - UNIVERSITETET I OSLO - THE UNIVERSITY OF EDINBURGH - - - EUR 4 167 054 - - - Anthropology of Human Security in Africa - - - EUR 4 167 054 - - - Denmark - Belgium - Norway - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - ANTHUSIA is a multi-disciplinary EJD in the Anthropology of Human Security in Africa proposed by a consortium of four universities in Aarhus, Edinburgh, Leuven and Oslo. Combining competences from Anthropology, Human Security - and African Studies It aims to foster talent relevant to current challenges and potentials of developing safe societies in Africa. By exploring different areas from a human security perspective, the research will provide insights into problems such - as expanding young populations, accelerated urbanisation, unequally distributed growth, recurring conflicts, persistent health problems, and refugee insecurity. A human security perspective shifts the focus from the security of nation states to the - safety and well-being of humans in their everyday lives. Human security problems, as well as growth rates in Africa have obvious ramifications for European home security and economy. Refugee crises due to human insecurity in the African continent are - likely to continue evolving in the future. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-EJD - European Joint Doctorates - - - Denmark - - - ANTHUSIA - - - H2020-MSCA-ITN-2017 - - - 764546 - - - - - BAR ILAN UNIVERSITY - BAR ILAN UNIVERSITY - - - EUR 1 499 345 - - - New Nuclear Medicine Imaging Radiotracer 64Cu(II) for diagnosing Hypoxia Conditions Based on the Cellular Copper Cycle - - - EUR 1 499 345 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Imaging of hypoxia is important in many disease states in oncology, cardiology, and neurology. Hypoxia is a common condition encountered within the tumour microenvironment that drives proliferation, angiogenesis, and - resistance to therapy. Despite on-going efforts to identify hypoxia, until now there is no clinically approved imaging biomarker, due to both low tumour uptake, and a low signal to background (S/B) ratio that affects the imaging quality. Nuclear - Medicine is using labelled radio-isotopes for PET/CT and SPECT imaging. These radio-tracers diagnose the metabolic processes in the body. Among these tracers, 18F-FDG is the most routinely used as a marker of glucose metabolism. However, not all - tumours consume glucose, and glucose consumption is not specific only for malignant tumours, which limits its application. Copper is a nutritional metal, recently examined as a radiotracer for hypoxia, owing to its to the oxidising environment. - Clinical and in-vivo studies on various 64Cu(II)-PET radiotracers resulted in controversial reports on the specificity of the current tracers for hypoxia imaging due to non-selective bio-distribution & low S/B ratio. This multidisciplinary - proposal focuses on the discovery of comprehensive signal pathways of the cellular copper cycle using advanced biophysical methods and a proprietary design of 64Cu(II) radiotracer. This radiotracer will be incorporated in the cellular copper cycle, - and will enable to selectively target the oxidising environment in tumours. The design of the new radiotracer is based on systematic structural & functional mapping of the copper binding sites to the various copper proteins and the visualisation - of the transfer mechanism. This new copper tracer should increase the selectivity of tumour uptake, stability, and improve bio-distribution. This project assimilates cold and hot chemistry and biology, while emphasising the clinical unmet need in - metal based radiotracer that form stable complexes. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Israel - - - CuHypMECH - - - ERC-2017-STG - - - 754365 - - - - - UNIVERSITA DEGLI STUDI DI TRIESTE - AARHUS UNIVERSITET - ISTITUTO NAZIONALE DI FISICA NUCLEARE - OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN - THE QUEEN'S UNIVERSITY OF BELFAST - TECHNISCHE UNIVERSITEIT DELFT - UNIVERSITY COLLEGE LONDON - UNIVERSITY OF SOUTHAMPTON - M-SQUARED LASERS LIMITED - - - EUR 4 371 473,75 - - - Testing the Large-Scale Limit of Quantum Mechanics - - - EUR 4 371 473,75 - - - Italy - Denmark - Italy - Austria - United Kingdom - Netherlands - United Kingdom - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Microscopic systems can be prepared in quantum configurations with no classical counterpart. Such a possibility seems precluded when the 'complexity' of the system grows towards the macroscopic domain: so far we have no - evidence of non-classical behavior of the macroscopic world. Why is it so? How is quantumness lost as we abandon the microscopic domain? These questions, which remain to date largely unanswered, address interesting and challenging goals of modern - research in physics, and serve the overarching goal of this project. TEQ will establish the large-scale limit of quantum mechanics by pursuing a novel research programme that aims at surpassing the current approach based on matter-wave - interferometry. Specifically, the TEQ Consortium will - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-01-2016-2017 - FET-Open research and innovation actions - - - RIA - Research and Innovation action - - - Italy - - - TEQ - - - H2020-FETOPEN-1-2016-2017 - - - 766900 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - INSTITUT CURIE - SEMMELWEIS EGYETEM - UNIVERSITAETSKLINIKUM FREIBURG - UNIVERSITEIT UTRECHT - HANSABIOMED LIFE SCIENCES OU - BIOINF2BIO LDA - GVS S.P.A. - AJ Innuscreen GmbH - UNIVERSITEIT GENT - - - EUR 3 724 252,20 - - - Training in Extracellular Vesicles: for benefit in Health and Disease - - - EUR 3 724 252,20 - - - Ireland - France - Hungary - Germany - Netherlands - Estonia - Portugal - Italy - Germany - Belgium - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - Exosomes and microvesicles/ectosomes, collectively termed extracellular vesicles (EV), have attracted much recent interest because of their potential functions, use as disease biomarkers and possible therapeutic exploitation. - Due to their enormous relevance, this relatively new field of research is quickly expanding. While Europe leads the field of EV research, there are still many gaps in knowledge that need to be addressed to ensure optimal exploitation of EVs from - health and Europe’s economic benefit. Addressing this, TRAIN-EV’s objective is to provide excellent and integrated multi-disciplinary and inter-sectoral training of a critical mass of ESRs of outstanding potential in the academic, clinical, and - industry/business components of exploiting EV, while performing novel cutting-edge research to address these gaps and generate new knowledge. This will be achieved by appointing 15 ESRs into 10 Beneficiary Organisations (6 academic; 4 non-academic), - with 4 additional Partner Organisations (3 non-academic; 1 academic) offering secondments, training and additional networking opportunities. All Participants have highly relevant and complementary medical/science/engineering/business expertise - –detailed within– that will collectively contribute to the training, to PhD level, of these 15 ESRs as academic and industry EV leaders for the future. - - 2021-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Ireland - - - TRAIN-EV - - - H2020-MSCA-ITN-2016 - - - 722148 - - - - - THE UNIVERSITY OF SHEFFIELD - THE UNIVERSITY OF SHEFFIELD - - - EUR 2 492 201 - - - Soundscape Indices - - - EUR 2 492 201 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Eighty million EU citizens are suffering from excessive environmental noise and billions of euros are being spent on noise control, under the EU Directive on Environmental Noise. Unfortunately, the conventional approach, i.e. - reduction of ‘sound level’, simply does not deliver the required improvements in quality of life. The growing field of ‘soundscape studies’ is addressing this gap by considering sound environment as perceived, in context, with an interdisciplinary - approach. However, soundscapes are hugely complex and measuring them as a basis for environmental design requires a step change to the discipline. This research aims to achieve a ground-breaking development through the establishment of ‘soundscape - indices’ (SSID), adequately reflecting levels of human comfort, the impact of which will be reminiscent of that of the Decibel scale created by Bell Systems a century ago. This will provide the underpinning science for soundscape in the field of - built environment, with wider intellectual goals of moving from noise control to soundscape creation. Key objectives, as coherent steps for achieving the main aim, are: (1) To characterise soundscapes, by capturing soundscapes and establishing a - comprehensive database, which will be a cornerstone for the proposed analysis, and an invaluable resource for scientists for years to come. (2) To determine key factors and their influence on soundscape quality based on the database, by conducting - laboratory psychological evaluation, physical/psychoacoustic factors analysis, and more importantly, to research at a physiological/biological level, including the use of functional magnetic resonance imaging. (3) To develop, test and validate the - soundscape indices, through analysing the influences by various factors, using a number of inter- & trans-disciplinary approaches. (4) To demonstrate the applicability of the soundscape indices in practice, by establishing frameworks for - soundscape prediction, design, and standardisation. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - SSID - - - ERC-2016-ADG - - - 740696 - - - - - UNIVERSITAT DE BARCELONA - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - UNIVERSITEIT UTRECHT - FLUIDIC ANALYTICS LIMITED - SWEETCH ENERGY - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 3 299 670 - - - TOWARDS NOVEL NANO-SCALE TECHNOLOGIES BASED ON PHORETIC FLOW EFFECTS - - - EUR 3 299 670,01 - - - Spain - United Kingdom - Netherlands - United Kingdom - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - - Most devices that transport bulk fluids make use of pressure gradients (`pumps’) or external forces (e.g. gravity powers hydro-electric turbines). Increasingly, modern technology is addressing problems where fluid transport - takes place in sub-micron sized channels, or in pores. The physical laws of transport in such channels are qualitatively different from those that determine bulk flow; they are poorly understood and, importantly, barely exploited. The aim of the - proposed research is to lay the basis for an entire novel technology where thermal gradients and concentration gradients along nano-sized channels are harnessed to drive devices that have no equivalent on the macroscopic scale. - - - 2021-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-01-2016-2017 - FET-Open research and innovation actions - - - RIA - Research and Innovation action - - - Spain - - - NANOPHLOW - - - H2020-FETOPEN-1-2016-2017 - - - 766972 - - - - - UNIVERSIDAD AUTONOMA DE MADRID - LANCASTER UNIVERSITY - TECHNISCHE UNIVERSITEIT DELFT - UNIVERSITY OF DURHAM - IBM RESEARCH GMBH - UNIVERSITAET BASEL - EIDGENOSSISCHE MATERIALPRUFUNGS- UND FORSCHUNGSANSTALT - - - EUR 3 118 272,50 - - - Quantum Interference Enhanced Thermoelectricity - - - EUR 3 118 272,50 - - - Spain - United Kingdom - Netherlands - United Kingdom - Switzerland - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Our vision is to demonstrate that room-temperature quantum interference effects, measured recently in single molecules, can be exploited in massively-parallel arrays of molecules and used to design ultra-thin-film - thermoelectric devices with unprecedented ability to convert waste heat to electricity using the Seebeck effect and to cool at the nanoscale via the Peltier effect. - - 2021-07-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-01-2016-2017 - FET-Open research and innovation actions - - - RIA - Research and Innovation action - - - Spain - - - QuIET - - - H2020-FETOPEN-1-2016-2017 - - - 767187 - - - - - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - - - EUR 2 000 000 - - - Visualizing the Conformational Dynamics of Proteins by Time-Resolved Electron Microscopy - - - EUR 2 000 000 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The function of many proteins involves large-amplitude domain motions that occur on a timescale of microseconds to millisecond. In the absence of tools to directly observe these dynamics, our understanding of the function of - proteins is necessarily incomplete and must frequently rely on extrapolation from known static structures. Here, the implementation of real-time imaging of single particle dynamics in liquid phase is proposed with both microsecond time resolution as - well as near-atomic spatial resolution. The experimental approach builds on several recent technological advances, namely the advent of Time-Resolved (“Four-dimensional”) Electron Microscopy, graphene liquid cell technology, and direct electron - detection cameras, which are combined with established single-particle reconstruction techniques in cryo-Electron Microscopy. Visualizing the conformational dynamics of proteins will fundamentally advance our understanding of these nanoscale machines - and has the potential to greatly benefit biomedical applications. - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Switzerland - - - ProteinDynamics - - - ERC-2017-STG - - - 759145 - - - - - VESTAS AIRCOIL AS - UNIVERSITY OF SOUTHAMPTON - - - EUR 1 093 151,52 - - - Integrated Design of Engineering Structures - - - EUR 1 093 151,52 - - - Denmark - United Kingdom - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - This collaborative doctoral training programme provides a model for the development of technology leaders, enabling them to apply scientific methods from academia to interdisciplinary industrial design. The project is driven - by the need for more efficient & lower emission engine systems. Heat exchangers in engines has been identified as a key enabling technology for low-emission power systems that is vital to the EU economy and is of great societal concern. - Development of high-performance heat exchangers is a complex engineering challenge requiring academic contributions at the forefront of engineering science, which will enhance the EU’s competitiveness by delivering economically and environmentally - improved products. Having identified charge air cooling as a key enabling technology for low-emission power systems, here we propose an integrated approach to doctoral training in the area of engineering design leading to four doctorates covering - diverse aspects of their mechanical engineering: structural vibration, stress & thermal analysis, additive manufacturing (AM), multifunctional metamaterials, fatigue & materials development. This project brings together a consortium of - industrial and academic partners in a novel and bespoke doctoral training programme that is multi-disciplinary in its content and inter-sectoral with regards to the employability of the technology leaders of tomorrow. The programme provides a - coherent training platform that inherently nurtures technical, creative and entrepreneurial skills. The central theme of Engineering Design within the programme enables us to build a training structure which is technically broad yet scientifically - rigorous, while having the academic depth expected of a doctoral programme. The programme provides mobility, industrial experience and academic foundations in an integrated manner that will uniquely equip our future technology leaders to contribute - to high-value innovation within EU industry. - - 2022-03-31, Grant Agreement signed - - - 2018-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-EID - European Industrial Doctorates - - - Denmark - - - InDEStruct - - - H2020-MSCA-ITN-2017 - - - 765636 - - - - - BAR ILAN UNIVERSITY - UNIVERZITA KARLOVA - EDINBURGH NAPIER UNIVERSITY - UNIWERSYTET JAGIELLONSKI - STICHTING FONTYS - LINKOPINGS UNIVERSITET - TAMPEREEN YLIOPISTO - AGE PLATFORM EUROPE - - - EUR 3 879 540,72 - - - An international, multi-disciplinary, multi-sectoral training network on ageism - - - EUR 3 879 540,72 - - - Israel - Czech Republic - United Kingdom - Poland - Netherlands - Sweden - Finland - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - - Europe has the largest percentage of older adults worldwide. Yet, there is a high prevalence of ageism; the complex and often negative construction of old age, in society at large, and among researchers and practitioners in - particular. In contrast to the wide prevalence of ageism, the majority of research, to date, has targeted racism and sexism and neglected to address ageism. A similar neglect is found on the policy side, as age is still not an explicit part of a U.N. - declaration of human rights. To address these shortcomings, EuroAgeism is focused on harmonising different theoretical and methodological disciplines in the field of ageism. It aims to bring together science and policy by creating an opportunity for - a true dialogue that will allow graduates of the program to capture positions as scientists, educators, science advisers, policy advocates, lobbyists, or legislators in the field of ageism. - - - 2021-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Israel - - - EuroAgeism - - - H2020-MSCA-ITN-2017 - - - 764632 - - - - - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - - - EUR 1 220 325 - - - Entangled Parliamentarisms: Constitutional Practices in Russia, Ukraine, China and Mongolia, 1905–2005 - - - EUR 1 220 325 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The project addresses the entangled histories of deliberative decision making, political representation and constitutionalism on the territories of the former Russian and Qing Empires and focuses on the cases of Russia, - Ukraine, China and Mongolia between 1905 and 2005. Employing the perspectives of the New Imperial History and Transcultural Studies, the project overcomes narrow state-centered approaches and takes advantage of multidisciplinary methodology crossing - history and political science. The project traces parliamentary developments, the interactions among imperial and post-imperial intellectuals and their engagement in global discussions, shared imperial legacies, mutual borrowings and references, - imperial and post-imperial political practices and translatability of concepts. It seeks to refute the stereotypes about inclinations towards democracy in particular national contexts by tracing relevant transnational practices and interactions and - providing a nuanced political and intellectual history of parliamentarism. The team of five researchers (the PI, three PhD students and a post-doctoral researcher), will discuss and develop five individual and three cooperative studies. The PI will - write a global history of parliaments and quasi-parliamentary institutions in Russia’s imperial formations (the State Duma of the Russian Empire, the congresses of soviets and the Federal Assembly of the Russian Federation). The three PhD students - with relevant language skills will focus on parliamentary developments in the Ukrainian, Chinese (including Hong Kong and Taiwan) and Mongolian contexts. The post-doctoral researcher will explore the translatability of concepts between Russian, - Chinese, Mongolian, Ukrainian and English. The three cooperative projects will focus on traditional institutions of deliberative decision making in the abovementioned contexts; the Communist International and institutional exchange; and the role of - parliaments in major social transformations. - - 2023-03-31, Grant Agreement signed - - - 2018-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - ENTPAR - - - ERC-2017-STG - - - 755504 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - Eidgenössische Technische Hochschule Zürich - UNIVERSITAET BASEL - Isthmus - UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6 - UNIVERSITY OF GLASGOW - UNIVERSIDAD POMPEU FABRA - BIOFACTION KG - - - EUR 2 968 817,50 - - - Microbial deployment of new-to-nature chemistries for refactoring the barriers between living and non-living matter - - - EUR 2 968 817,50 - - - Spain - Switzerland - Switzerland - France - France - United Kingdom - Spain - Austria - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - This Project is about bringing a suite of chemical reactions (and its related non-biological compounds and elements) to the biological fold (i.e. their 'biologization') by going beyond the Central Dogma of Molecular Biology - (DNA→ RNA→ proteins→ metabolism) through both tuning and overcoming the uni-directionality of the information flow. To reverse-engineer reactions into a biological code, the utility function of the chemical process of interest will be progressively - coupled to the fitness function of a live carrier (e.g. an engineered, synthetic or cyborg-ized bacterial chassis), the intermediate steps being supported by automated chemo-robots. The new-to-nature reactions (NTN) pursued within the MADONNA - lifetime as case studies will include CO2 capture and recruitment of elemental silicon to become part of essential organo-Si metabolites. Along with the development of the new reactions, the research agenda of the Project will also include the [i] - modelling and prediction on the impact of the new biotransformations on the overall functioning of the Biosphere once/if adopted at a large scale by the industrial sector and [ii] design of environmental simulators for evaluating the performance and - evolution of the new biological reactions under given physico-chemical settings. With such approaches, MADONNA aims to fill many of the gaps between the 3 types of global-scale processing of chemical elements operating in our planet: Geochemical, - Biological and Industrial. The scale of applications of the foundational technologies developed herein (which spin themselves much beyond CO2 and silicon) is unprecedented and a large number of societal ramifications including ethical, security, - safety, economic, governance and public perceptions aspects at stake will be included. If successful, MADONNA will enable an entirely new type of sustainable industry in which many types of waste become assets instead of liabilities. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-01-2016-2017 - FET-Open research and innovation actions - - - RIA - Research and Innovation action - - - Spain - - - MADONNA - - - H2020-FETOPEN-1-2016-2017 - - - 766975 - - - - - TECHNISCHE UNIVERSITAET WIEN - TECHNISCHE UNIVERSITAET WIEN - FACULTY OF SCIENCE UNIVERSITY OF ZAGREB - - - EUR 2 133 950 - - - The Janus-face of the localized carrier in cuprates: Generating the pseudogap and high temperature superconductivity - - - EUR 2 133 950 - - - Austria - Austria - Croatia - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The phenomenon of high-temperature (high-Tc) superconductivity (SC) is one of the most exciting, thoroughly investigated yet still unresolved problems in physics. A major difficulty in understanding high-Tc systems lies in the - complexity of the materials and phase diagram. The delicate balance between material specific properties, disorder and the number of electronic phases superimpose makes it hard to identify the leading interactions. Consequently, theoretical models - attempting to describe the high-Tc SC are significantly disparate and identifying the mechanism of SC at elevated temperatures is full of hardship. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Austria - - - TheONE - - - ERC-2016-COG - - - 725521 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 239 860,80 - - - Morphology of Lithic Artifacts: Experimental and Morphometric Approaches - - - EUR 239 860,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - MORPHOLITHEX addresses one of the major research questions in prehistoric stone tool technologies - what are the crucial variables that knappers control to determine the form of their stone artifacts? Specifically, the project - investigates the effects of variables that are under the direct control of the knapper, namely various platform management strategies and the morphology of the core surface, on the size and shape of the product. The project uses a novel combination - of methods: the knapping process is simulated in an experimental setting that uses an apparatus that enables independent variables to be controlled and measured to isolate their effects on the final results; three-dimensional geometric morphometric - methods are used to explore the size and shape of the blanks produced by the experiment; and advanced statistical modeling is used correlate the experimental predictors to the shape and size of the resulting blanks. The specific concentration is on - platform management and core surface morphologies common in Levallois blank production, a technology that is present across the Old World during the last 300 thousand years, and is common during the rise and expansion of modern humans around 50 - thousand years ago. The goal is to construct a more comprehensive model to account for morphological variation in stone tools and to validate this model using replicative and archeological collections. This quantitatively driven research integrates - several of the most advanced approaches in our field and aims to significantly contribute to our understanding of the elementary principles of producing stone tools in prehistory. It further intends to make methodological advancements in controlled - experiments for investigating the production of stone tools, as well as developing protocols for analyzing stone tool shape and size with geometric morphometrics. - - 2020-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Germany - - - MORPHOLITHEX - - - H2020-MSCA-IF-2016 - - - 751125 - - - - - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - - - EUR 149 973 - - - Networking and Care: Helping young people with mental health problems through outreach and eHealth - - - EUR 149 973 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The aim of this project is to develop a mobile app which facilitates access to mental health services and treatments for young people with mental health problems; and to assess its feasibility, acceptability and potential - clinical and cost-effectiveness. If successful, the app would: (1) increase access to mental health care by providing links to relevant existing services; (2) increase access to relevant evidence-based mobile health interventions and to address - barriers to care and (3) allow individuals to review services they have used and provide feedback which can be accessed by other app users. - - 2019-03-31, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - NCore - - - ERC-2016-PoC - - - 737569 - - - - - KOBENHAVNS UNIVERSITET - - - EUR 278 227,80 - - - Mind the Gut: Molecular Markers of Microbiome Evolution - - - EUR 278 227,80 - - - Denmark - - - Higher or Secondary Education Establishments - - What is the role of our microbial partners in our evolution? Does the microbiome evolution reflect major events of human history? Despite increasing evidence that the gut microbiome plays an essential role in multiple core - aspects of human biology, little is known about how the human-gut community co-evolved. The role of the microbiome in human evolution and speciation has been historically overlooked, in part due to the challenge of obtaining microbiome data from - ancient material. However, understanding the co-evolution of the human-gut ecosystem requires a time-series approach associated with the major defining moments in human evolution such as migrations, admixture, domestication, industrialization and - globalisation. Under favourable conditions some archaeological substrates such mummified tissues, coprolites and dental calculus have potential to shed some light on ancient microbiomes. - - - 2020-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Denmark - - - MIND THE GUT - - - H2020-MSCA-IF-2016 - - - 750860 - - - - - FUNDACION BCMATERIALS - BASQUE CENTRE FOR MATERIALS, APPLICATIONS AND NANOSTRUCTURES - FUNDACION BCMATERIALS - BASQUE CENTRE FOR MATERIALS, APPLICATIONS AND NANOSTRUCTURES - - - EUR 1 878 085 - - - Molecularly Engineered Materials and process for Perovskite solar cell technology - - - EUR 1 878 085 - - - Spain - Spain - - - Research Organisations - Research Organisations - - Societal pressure to develop inexpensive yet efficient solar energy conversion requires a new approach. Recently emerged organic-inorganic perovskites, offer to harvest light at cost effective price. Perovskites hold merits to - the existing materials, however, a fundamental challenge for high performance devices is to optimize the crystals for maximize charge carrier generation and minimize recombination losses. Their widespread use is, however, limited by insufficient - stability, scalability and reproducibility. We have recently developed new concepts to fabricate efficient and stable perovskite solar cells at lab scale that are potentially up-scalable to industrial production. MOLEMAT will accomplish this by, - pioneering innovative methods and will demonstrate that molecularly engineered materials enable the tuning of the charge transport and interface. Our interdisciplinary approach, combining materials science, chemistry, device physics and engineering, - will not only lead to improvements in the performance and stability of perovskite solar cell beyond 24% at lab scale, but will also provide deep insights in the functioning of solar cells. The success of MOLEMAT will rapidly advance the field by - enabling reproducible and stable performance adding a significant value with respect to current state of the art. However, for making it marketable product, several developments are required and the MOLEMAT targets will provide relevant answers to - three key limitations: encapsulation, stability and cost competitive materials. MOLEMAT envisages the development of 30×30 cm2 modules, with a power conversion efficiency of c.a 18% and a lifetime of 10+ years. MOLEMAT is divided into two parallel - research directions, a fundamental research line, dealing with rational design of materials and to gain its understanding. Simultaneously an applied research line targets the development of module by the identification of scale up process to pave the - way for its industrialization. - - 2022-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Spain - - - MOLEMAT - - - ERC-2016-COG - - - 726360 - - - - - PANEPISTIMIO KRITIS - PANEPISTIMIO KRITIS - - - EUR 150 000 - - - Making it happen - Scalable biphasic reactions using a nebulizer-driven continuous flow reactor - - - EUR 150 000 - - - Greece - Greece - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The original ERC grant focused on proving the power that oxygen from the air had in synthesis when its light-excited state was exploited. During the ERC program, we were able to show how simple & readily accessible start - materials could be transformed into high value-high interest chemicals through straightforward “one pot” operations. We were also able to show that the diversity of structures accessible using this chemistry is remarkable. Furthermore, it is highly - sustainable; representing a very efficient, benign & extremely low waste approach to the production of sought-after chemical frameworks. However, one problem prevailed. While it worked exceptionally well on a small research scale, its overall - usefulness and its industrial relevance were severely curtailed by scale-up issues, even when the latest continuous flow technologies were applied. The need to achieve good light penetration, combined with the poor solubility of oxygen, seemed to - castrate the potential of this chemistry to provide global solutions. A key breakthrough was made towards the end of the ERC program with the realization that creating and projecting a cloud (using a nebulizer to make fine droplets) into a light - filled chamber could solve ALL the problems and lead to large scale reactions. With the current proposal, we seek to explore and fully automate this highly innovative nebulizer process in order to develop a robust prototype reactor with excellent - prospects for further dimension enlarging (to industrial pilot plant scales & beyond). Furthermore, it is obvious that this “nebulizer fix” may also be superbly suited to other biphasic reactions. Our plan has the support of pharmaceutical giant - AstraZeneca in the form of an automation expert who will act as mentor to the program. The PI & the advisory team will pursue a number of different commercialization opportunities delineated herein and look at how best to exploit and amplify the - impact of the extremely efficient prototype reactor(s). - - 2019-06-30, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Greece - - - NebuFlox - - - ERC-2017-PoC - - - 779437 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - TECHNISCHE UNIVERSITEIT EINDHOVEN - QUEEN MARY UNIVERSITY OF LONDON - THE UNIVERSITY OF MANCHESTER - UNIVERSITEIT GENT - THE UNIVERSITY OF READING - HUMBOLDT-UNIVERSITAET ZU BERLIN - PSA AUTOMOBILES SA - IONERA TECHNOLOGIES GMBH - - - EUR 3 926 899,80 - - - Monomer sequence control in Polymers : Toward next-generation precision materials - - - EUR 3 926 899,80 - - - France - Netherlands - United Kingdom - United Kingdom - Belgium - United Kingdom - Germany - France - Germany - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The aim of the project “Euro-Sequences” is to establish a multidisciplinary training network on the emerging topic of sequence-controlled polymers. It has been shown during the last 5 years that such polymers open up - unprecedented options for the future of manmade materials. Indeed, similarly to biopolymers such as DNA and proteins, synthetic sequence-controlled polymers contain precisely engineered chain-microstructures that allow a fine control over their - molecular, nanoscopic and macroscopic properties. For instance, these new types of polymers are relevant for applications in molecular data storage, catalysis, and nanomedicine. However, this field of research is young and therefore, fundamental and - applied research is still mandatory. Thus, it seems timely and appropriate to federate top-European researchers working on that topic. The proposed network is composed of 7 academic partners and 2 companies and connects researchers with complementary - expertise in areas such as organic chemistry, polymer synthesis, supramolecular chemistry, physico-chemistry and materials science. This multidisciplinary network will focus on different scientific aspects. A first important objective will be the - development of facile and rapid chemical methods for ‘writing’ molecular information on polymers. In addition, analytical techniques that allow characterization and sequencing of polymers will be studied. The folding and self-assembly of - sequence-controlled polymers will be also examined in order to understand the correlation between controlled primary structure and higher levels of organization. Eventually, a crucial aim of this project will be the conception of new types of - plastics materials. This network will be a unique scientific environment for training PhDs. The students will conduct their research in top-European laboratories and will receive a complete training, including lectures and summer schools, on polymer - chemistry, supramolecular chemistry and biomaterials. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - France - - - EURO-SEQUENCES - - - H2020-MSCA-ITN-2014 - - - 642083 - - - - - CITY UNIVERSITY OF LONDON - CHALMERS TEKNISKA HOEGSKOLA AB - TECHNISCHE UNIVERSITEIT DELFT - TECHNISCHE UNIVERSITAET MUENCHEN - INSTITUT POLYTECHNIQUE DE GRENOBLE - WAERTSILA NETHERLANDS B.V. - Delphi Diesel Systems LTD - AVL LIST GMBH - - - EUR 3 939 999,12 - - - Development and experimental validation of computational models for cavitating flows, surface erosion damage and material loss - - - EUR 3 939 999,12 - - - United Kingdom - Sweden - Netherlands - Germany - France - Netherlands - United Kingdom - Austria - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Cavitation, described as the formation of vapour/gas bubbles of a flowing liquid in a region where the pressure of the liquid falls below its vapour pressure, often leads to vibration and damage of mechanical components, for - example, bearings, fuel injectors, valves, propellers and rudders, impellers, pumps and hydro turbines. Cavitation erosion when experienced, normally leads to significant additional repair and maintenance costs or component replacement. Even if - erosion problems can be avoided by design or operation, most often the performance of the systems is sub-optimal because countermeasures by design are needed to prevent cavitation problems. Despite the long-lasting problems associated with - cavitation, computational models that could simulate cavitation and identify locations of erosion are still not thoroughly developed. The proposed interdisciplinary training and research programme aims to provide new experimental data and an - open-source simulation tool for hydrodynamic cavitation and induced erosion. Insight into the detailed bubble collapse mechanism leading to surface erosion will be realised through DNS simulations, which are now feasible by the significant progress - in fluid flow computational methods and parallel simulations. Information from such models will be implemented as sub-grid scale models of URANS and LES approaches, typically employed for cavitation simulation at engineering scales. Model validation - will be performed against new advanced X-ray, laser diagnostics and high speed imaging measurements to be performed as part of this project. Application of the developed models to cases of industrial interest includes fuel injectors, marine - propellers, hydro-turbines, pumps and mechanical heart valves. From this understanding the development of methodologies for design of cavitation-free or remedial measures and operation of devices suffering from cavitation erosion can then be - established for the benefit of the relevant communities. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - CaFE - - - H2020-MSCA-ITN-2014 - - - 642536 - - - - - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - - - EUR 1 473 175 - - - Sublinear Algorithms for Modern Data Analysis - - - EUR 1 473 175 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Designing efficient algorithms for fundamental computational tasks as well as understanding the limits of tractability has been the goal of computer science since its inception. Polynomial runtime has been the de facto notion - of efficiency since the introduction of the notion of NP-completeness. As the sizes of modern datasets grow, however, many classical polynomial time (and sometimes even linear time) solutions become prohibitively expensive. This calls for sublinear - algorithms, i.e. algorithms whose resource requirements are substantially smaller than the size of the input that they operate on. - - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Switzerland - - - SUBLINEAR - - - ERC-2017-STG - - - 759471 - - - - - UNIVERSIDADE DE EVORA - UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA - BEN-GURION UNIVERSITY OF THE NEGEV - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - POLITECNICO DI TORINO - UNIVERSITE D'AVIGNON ET DES PAYS DE VAUCLUSE - UNIVERSIDAD DE BURGOS - UNIVERSITE BORDEAUX MONTAIGNE - INSTITUTE OF COMMUNICATION AND COMPUTER SYSTEMS - - - EUR 3 298 257,36 - - - European Doctorate in ARchaeological and Cultural Heritage MATerials science - - - EUR 3 298 257,36 - - - Portugal - Italy - Israel - Spain - Italy - France - Spain - France - Greece - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - The ED-ARCHMAT (European Doctorate in Archaeological and Cultural Heritage Materials Science) EJD aims to train a new generation of creative and entrepreneurial ESR able to face current and future challenges in - Archaeological/Cultural Heritage protection and management and to convert knowledge and ideas into products and services for economic and social benefit. The study, management and optimization of Archaeological and CH sites and objects is a sector - with a strong multidisciplinary connotation. Accordingly the ED-ARCHMAT international consortium includes HEI, SME, Museums, Conservations Labs (such as the GCI in LA), and IT/Business Schools and proposes a coherent joint doctoral program aiming at - overcoming national, sectoral and inter-disciplinary boundaries in PhD research in the field of Archaeometry/Conservation Science. The ED-ARCHMAT EJD will have a strong ESR mobility component, with the final goal of leading to lasting PhD-level - cooperation between beneficiaries and partners. The EJD will also strengthen the transmission and exploitation of knowledge and enhance the innovation process in the general CH area where the increasing development of more sophisticated chemical and - physical analytical techniques and of ICT have highlighted the existence of a knowledge gap that needs to be filled. The successful ED-ARCHMAT ESR will acquire innovative skills and key competence spanning across the Humanities, Materials Science, - Business and Management fields, acquiring the professional figure of Conservation Scientist 1) Conservation science ; 2) Development of Diagnostic and Monitoring tools; 3) New Conservation Materials and Methods: characterization of artifacts - degradation mechanisms, performance evaluation of new materials, decision making techniques, 4) Equipments : skills in the utilization of different instrumentations, 5) Energy efficient and sustainable solutions for CH materials; 6) Management and - entrepreneurship in Cultural Heritage - - 2022-03-31, Grant Agreement signed - - - 2018-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-EJD - European Joint Doctorates - - - Portugal - - - ED-ARCHMAT - - - H2020-MSCA-ITN-2017 - - - 766311 - - - - - UNIVERSITEIT MAASTRICHT - FONDAZIONE IRCCS ISTITUTO NAZIONALE DEI TUMORI - UNIVERSITE DE LIEGE - ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM - DEUTSCHES KREBSFORSCHUNGSZENTRUM - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - ONCORADIOMICS - MIRADA MEDICAL LTD - PERSPECTUM DIAGNOSTICS LTD - HEALTH INNOVATION VENTURES BV - - - EUR 3 860 059,68 - - - A new era in personalised medicine: Radiomics as decision support tool for diagnostics and theragnostics in oncology - - - EUR 3 860 059,68 - - - Netherlands - Italy - Belgium - Netherlands - Germany - France - Belgium - United Kingdom - United Kingdom - Netherlands - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The high degree of tumour (genomic and phenotypic) heterogeneity influences patient’s response to therapy and hampers wide deployment of personalised medicine for cancer treatment. Thus, there is an imperative need for new - technologies that can accurately detect tumour heterogeneity, allow for patient stratification and assist clinicians in providing the right diagnosis and treatment for the right patient. PREDICT’s mission is to address this huge unmet need. - - 2021-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Netherlands - - - PREDICT - - - H2020-MSCA-ITN-2017 - - - 766276 - - - - - UNIWERSYTET JAGIELLONSKI - JOHANNES GUTENBERG-UNIVERSITAT MAINZ - FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA - UNIVERSITY OF YORK - UNIVERSITAET ULM - UNIVERSITY OF SOUTHAMPTON - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - UNIVERSITE LYON 1 CLAUDE BERNARD - UNIVERSITA DEGLI STUDI DI TORINO - - - EUR 2 794 786,20 - - - Zero and ultra-low field nuclear magnetic resonance - - - EUR 2 794 786,20 - - - Poland - Germany - Italy - United Kingdom - Germany - United Kingdom - United Kingdom - France - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Chiara Andreoli - Tel.: +3901071781854 - Fax: +39 010 7170817 - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Nuclear magnetic resonance (NMR) is a powerful technique employed in many areas of modern science and industry. While a seemingly indispensable element of NMR is a strong (>5 T) magnetic field, recent progress in physics - and chemistry have enabled detection of NMR signals at ultra-low and truly zero magnetic fields. This completely reverses conditions under which spin-dynamics are investigated and gives access to information unavailable in conventional NMR. A - secondary horizon is microscopic low-field magnetic sensors that probe NMR signals of a single molecule, and provide interesting information about molecular dynamics and structures not accessible with conventional NMR. The address of specific - molecular sites is a step towards realizing single-molecule quantum information storage. - - 2022-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Poland - - - ZULF - - - H2020-MSCA-ITN-2017 - - - 766402 - - - - - ROYAL COLLEGE OF SURGEONS IN IRELAND - UNIVERSITAET STUTTGART - LUXEMBOURG INSTITUTE OF HEALTH - VIB - Institut du Cerveau et de la Moelle épinière - ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM - GENEXPLAIN GMBH - INFORMATION TECHNOLOGY FOR TRANSLATIONAL MEDICINE (ITTM) SA - AGILENT TECHNOLOGIES BELGIUM NV - - - EUR 3 836 772 - - - Exploiting GLIOblastoma intractability to address European research TRAINing needs in translational brain tumour research, cancer systems medicine and integrative multi-omics - - - EUR 3 836 772 - - - Ireland - Germany - Luxembourg - Belgium - France - Netherlands - Germany - Luxembourg - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Glioblastoma (GBM) is the most frequent, aggressive and lethal of all brain tumours. It has a universally fatal prognosis with 85% of patients dying within two years. New treatment options and effective precision medicine - therapies are urgently required. This can only be achieved by focused multi-sectoral industry-academia collaborations in newly emerging, innovative research disciplines. GLIOTRAIN will exploit the intractability of GBM to address European applied - biomedical research training needs. The ETN, which comprises 9 beneficiaries and 14 partner organisations from 8 countries, will train 15 innovative, creative and entrepreneurial ESRs. The research objective of GLIOTRAIN is to identify novel - therapeutic strategies for application in GBM, while implementing state of the art next generation sequencing, systems medicine and integrative multi-omics to unravel disease resistance mechanisms. Research activities incorporate applied systems - medicine, integrative multi-omics leveraging state of the art platform technologies, and translational cancer biology implementing the latest clinically relevant models. The consortium brings together leading European and international academics, - clinicians, private sector and not-for-profit partners across GBM fields of tumour biology, multi-omics, drug development, clinical research, bioinformatics, computational modelling and systems biology. Thus, GLIOTRAIN will address currently unmet - translational research and clinical needs in the GBM field by interrogating innovative therapeutic strategies and improving the mechanistic understanding of disease resistance. The GLIOTRAIN ETN addresses current needs in academia and the private - sector for researchers that have been trained in an environment that spans translational research, medicine and computational biology, and that can navigate confidently between clinical, academic and private sector environments to progress applied - research findings towards improved patient outcomes. - - 2021-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Ireland - - - GLIOTRAIN - - - H2020-MSCA-ITN-2017 - - - 766069 - - - - - KARLSRUHER INSTITUT FUER TECHNOLOGIE - KARLSRUHER INSTITUT FUER TECHNOLOGIE - - - EUR 150 000 - - - CellPrintArray – on-demand nano-scale printing of live cells and compounds for miniaturized cell screening applications - - - EUR 150 000 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The goal of this ERC-PoC project is to develop a prototype system that will enable the addition of libraries of drugs and biochemical molecules, reagents and cells from a 96 source plate directly to individual compartments of - the target Droplet Microarray (DMA). The system should have controlled atmosphere (CO2, humidity, temperature) and should allow for dispensing controlled volumes (3-500 nL per experiment) and cell numbers (1-100 per experiment) into individual - droplets. We aim to create and evaluate this system for applications commonly performed in pharmaceutical companies and screening centers to enable them to perform miniaturized and more predictive high throughput screenings using physiologically - relevant cells such as primary cells, stem cells, biopsy-derived cells and other scarce cell types. The system should allow high-throughput screenings with patient derived cells and therefore will open new possibilities in drug discovery and - personalized medicine. - - 2019-03-31, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Germany - - - CellPrintArray - - - ERC-2017-PoC - - - 768929 - - - - - EBERHARD KARLS UNIVERSITAET TUEBINGEN - UNIVERSITA DEGLI STUDI DI MODENA E REGGIO EMILIA - LUNDS UNIVERSITET - HASKOLI ISLANDS - SP PROCESS DEVELOPMENT AB - INOCURE SRO - OCULIS EHF - PAMGENE INTERNATIONAL BV - - - EUR 3 327 702,84 - - - Educating the next generation of scientists in translational medicine: Focus on eye diseases - - - EUR 3 327 702,84 - - - Germany - Italy - Sweden - Iceland - Sweden - Czech Republic - Iceland - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Medicine today experiences a gap between basic research and successful clinical translation that delays establishment of urgently needed therapies. This is very clearly so in blinding retinal degenerations (RDs), where most - are yet untreatable, even with a wealth of basic and pre-clinical research data available. To address this problem, transMed proposes an innovative programme to educate “translational researchers” that focuses on the bench-to-bedside development of - treatments for RD. - - 2021-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - transMed - - - H2020-MSCA-ITN-2017 - - - 765441 - - - - - UNIVERSITY OF DUNDEE - - - EUR 195 454,80 - - - Development of screw anchors for floating Marine Renewable Energy system arrays incorporating anchor sharing - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Classical anchoring solutions are inappropriate for the development of new marine renewable energy devices (wind/waves/tides). They are too expensive and not efficient. Organising devices in arrays is a solution where adjacent - devices share an anchor. It reduces the total number of anchors necessary and the overall cost. In turn the loading applied to an anchor is a complex combination of horizontal and uplift cyclic loads. Screw anchors are piles which are fitted with one - or several helices at their end. They are installed into the soil by applying a torque and are assumed to have an excellent resistance against uplifting. - - 2019-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SAFS - - - H2020-MSCA-IF-2016 - - - 753156 - - - - - ARISTOTELIO PANEPISTIMIO THESSALONIKIS - ISTITUTO SUPERIORE DI SANITA - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - INSTITUT JOZEF STEFAN - UNIVERSITE PARIS DESCARTES - UNIVERSITAT ROVIRA I VIRGILI - KENTRO TOXIKOLOGIAS ANONIMI ETAIRIA SYMVOULEYMKES DIAGNOSTIKES KAI ERGASTIRIAKES YPIRESIES TOXIKOLOGIAS FARMAKOLOGIAS KAI BIOIATRIKIS - ZELENA INFRASTRUKTURA DRUSTVO S OGRANICENOM ODGOVORNOSCU ZA ZASTITU OKOLISA I PROSTORNO UREDENJE - Istituto Universitario di Studi Superiori di Pavia - ISTITUTO DI RICOVERO E CURA A CARATTERE SCIENTIFICO BURLO GAROFOLO - - - EUR 3 493 845 - - - EXPLORING THE NEUROLOGICAL EXPOSOME - - - EUR 3 493 845 - - - Greece - Italy - Spain - Slovenia - France - Spain - Greece - Croatia - Italy - Italy - - - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - The main objective of NEUROSOME is to develop an integrative biology-based framework starting from human biomonitoring data to unravel causal associations among the genetic predisposition, cumulative exposure to multiple - environmental chemicals and neurological disorders. The project brings together beyond- the-state-of-the-art advances in human biomonitoring and systems biology, exposure monitoring and toxicological testing technologies and advanced tools for - computational analyses of the exposure-to-health effect continuum following an exposome paradigm. The NEUROSOME methodology will be applied in population studies across different exposure settings to neurotoxicants (metals and persistent organics) in - Europe. This will improve scientific knowledge on cause and-effect relations between environmental stressors and neurodevelopmental disorders taking into account exposure and health effect modification due to intrinsic (e.g. genetic susceptibility) - and extrinsic (e.g. diet and socioeconomic status) factors. New standards for human biomonitoring data interpretation in conjunction with environmental and exposure information will be developed for ready use in chemical mixture risk assessment. - - 2021-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Greece - - - NEUROSOME - - - H2020-MSCA-ITN-2017 - - - 766251 - - - - - UNIVERSITY OF HULL - - - EUR 195 454,80 - - - A Novel Hybrid Photovoltaic–Thermoelectric Power Generation System Employing the Flat-plate Micro-channel Heat Pipe - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Integrating a thermoelectric (TE) module into a PV module can convert the accumulated heat of the PV into electricity, thus increasing electricity yield of the unit. A traditional spectrum integration PV-TE unit, by coupling - the equal sized TE and PV modules, can harvest 30% more electricity than the PV unit alone. However, the pair-arrangement between the PV and TE modules appears to be economically unfeasible, owing to the significantly higher cost and lower power - output of the TE module. By introducing a low cost and high efficiency micro-channel heat pipe (MCHP) and placing the PV onto the evaporator of the MCHP and TE underneath its condenser, the system’s cost will be significantly reduced while its power - output remains almost same as to the pair-arranged PV-TE system. The proposed MSCA programme aims to characterise and optimise the novel PV-TE-MCHP, by integrating the excellence of the host applicant in PV and MCHP and the expertise of the - researcher applicant in TE, solar energy and heat transfer technology, and by sharing the knowledge of both the host and researcher applicants in PV/T and computer simulation. The tasks involved include (a) conceptual design; (b) computer - modelling/optimisation; (c) prototype construction & testing; and (d) economic and environmental performance analyses. As a result, the programme will deliver a novel PV-TE-MCHP prototype that, compared to the existing PV-TE systems, has a - significantly lower cost while the electrical output remains the same. From the MSCA point of view, the project will attract an experienced researcher with particular knowledge in PV/T, TE and computer simulation into Europe. This will (a) achieve - transfer of knowledge from outside into Europe, thus helping growing EU’s knowledge-based economy and society; (b) develop a long term contact network among the researcher, host organisation, partner organisation and other associated institutions; - and (c) enable advanced training to the researcher. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - PV-TE-MCHP - - - H2020-MSCA-IF-2016 - - - 745614 - - - - - TECHNISCHE UNIVERSITAET BERLIN - MATHCONSULT GMBH - UNIVERSITAT LINZ - MICROGATE SRL - CONSORCIO INSTITUTO TECNOLOXICO MATEMATICA INDUSTRIAL ITMATI - INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE - UNIVERSITAET BREMEN - BERGISCHE UNIVERSITAET WUPPERTAL - STMICROELECTRONICS SRL - FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG - POLITECNICO DI MILANO - SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI DI TRIESTE - FORSCHUNGSVERBUND BERLIN EV - - - EUR 2 785 605,48 - - - Reduced Order Modelling, Simulation and Optimization of Coupled systems - - - EUR 2 785 605,48 - - - Germany - Austria - Austria - Italy - Spain - France - Germany - Germany - Italy - Germany - Italy - Italy - Germany - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - The development of high quality products and processes is essential for the future competitiveness of the European economy. In most key technology areas product development is increasingly based on simulation and optimization - via mathematical models that allow to optimize design and functionality using free design parameters. Best performance of modelling, simulation and optimization (MSO) techniques is obtained by using a model hierarchy ranging from very fine to very - coarse models obtained by model order reduction (MOR) techniques and to adapt the model and the methods to the user-defined requirements in accuracy and computational speed. - - 2021-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-EID - European Industrial Doctorates - - - Germany - - - ROMSOC - - - H2020-MSCA-ITN-2017 - - - 765374 - - - - - Academisch Medisch Centrum bij de Universiteit van Amsterdam - REGION NORDJYLLAND (NORTH DENMARK REGION) - OPTIMEDIS AG - UNIVERSITY OF SURREY - SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO SANT'ANNA - BUDAPESTI CORVINUS EGYETEM - - - EUR 3 355 245 - - - Healthcare Performance Intelligence Professionals - - - EUR 3 355 245 - - - Netherlands - Denmark - Germany - United Kingdom - Italy - Hungary - - - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Balancing between improving population health, delivering quality care for individuals, and containing costs is a timely social/economical challenge in Europe. There is great potential achieving this through healthcare (HC) - system performance intelligence optimizing effective use of available HC data in countries. Effective implementation of HC performance intelligence (HPI) by skilled professionals will improve integrated service delivery; patient engagement; equality - in access to HC; health outcomes; and reduce waste in HC. Translating HC data into meaningful, valid, actionable performance intelligence that is transferrable into actions to improve HC systems requires multidisciplinary skills & innovative - competencies; currently not well developed in training programmes and the scientific community and missing in today’s European HC market. The ETN for HPI Professionals (HealthPros) fills this gap and directly impacts the European Research Area by - training innovative “Healthcare Performance Intelligence Professionals” uniting a multidisciplinary consortium tackling private, public, academic sectors.13 ESRs will be trained in multidisciplinary innovative scientific technical and complementary - skills, seconded to private / public / academic HC sectors in multiple countries and build relations with potential future employers. 5 ESRs work on PhD projects related to HC performance measurement optimizing the use of available registry and - administrative data and applying statistical models to provide actionable input to HC performance management. 4 ESRs work on PhDs to translate performance intelligence into value-creating HC governance mechanisms; 4 ESRs work on PhDs aimed to impact - the actual use of performance intelligence by different end-users. ESRs will have unique HC data access. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Netherlands - - - HealthPros - - - H2020-MSCA-ITN-2017 - - - 765141 - - - - - CARDIFF UNIVERSITY - - - EUR 195 454,80 - - - Mathematical models of bone externally excited remodelling - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - For describing complex systems as bone tissue, with their inner interactions and their interactions with environment the mathematical models become even more complex, that puts demands on theories, methods and assumptions used - and the efficiency of numerical methods employed for solving as well as the management of data. The complexity of bone models depends not only on the number of parameters describing different biochemistry and Multi-physics influences but also on - different time scales and rate of periodicity of processes involved. In structural analysis non-linearity plays important role for realistic description of real world phenomena. Incorporated the parametric nonlinear analysis of periodically excited - hybrid systems into a structural models of bone would be a great advantages for prediction of a more realistic situation for description of the bone mass distribution, delay in the osteoblasts and osteoclasts coupling, osteocytes transferring of - signals and more other issues related to the bone adaptively and strength. The aim of the project would be that on the base of existing level of known parameters in bone turnover guided by external loading provide an analytical approach to be solve - and interpreted for real description and prediction of bone adaptive behavior. Hybrid systems treat cellular level as discrete system of particles described with system of coupled ordinary differential equations and environmental conditions as a - continuous system described with a system of coupled partial differential equations affected with different external signals. The established, measured and explored model will also give an approach closer to the realistic situation and real needs and - suggestions for patients with bone problems but also for those who want to have healthy and strong skeleton. - - 2019-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - MMoBEER - - - H2020-MSCA-IF-2016 - - - 752793 - - - - - KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW - PHILIPPS UNIVERSITAET MARBURG - EBERHARD KARLS UNIVERSITAET TUEBINGEN - BOTANICKY USTAV AV CR, V.V.I. - INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE - INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT - ECSEQ GMBH - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - IGA TECHNOLOGY SERVICES SRL - MARTIN-LUTHER-UNIVERSITAET HALLE-WITTENBERG - GREGOR-MENDEL-INSTITUT FÜR MOLEKULARE PFLANZENBIOLOGIE GMBH - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 3 784 150,80 - - - Epigenetic Diversity in Ecology - - - EUR 3 784 150,80 - - - Netherlands - Germany - Germany - Czech Republic - France - France - Germany - Spain - Italy - Germany - Austria - Germany - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Plants are the foundation of all ecosystems and they provide humans with essential services. Unprecedented rates of global environmental change are now putting plants under increased risk, and it is important to understand the - capacity of plants to adapt to rapid change. EPIDIVERSE takes a cross-disciplinary approach to investigate the role that epigenetic mechanisms, specifically DNA methylation, play in plant adaptation. Understanding the epigenetic contribution to - adaptation will help to predict species responses to global warming and can open new directions for sustainable agriculture and crop breeding. In EPIDIVERSE, a consortium of academic and entrepreneurial PIs will train 15 ESRs to become a first - generation of expert eco-epigeneticists, equipping them with the interdisciplinary skills - molecular, (epi)genomic, ecological and bioinformatics - to successfully tackle this new research area. Training in leading academic groups and in life - sciences companies will emphasize empirical and informatics skills to become fluent and creative in extracting knowledge from big ‘omics data in natural contexts. In so doing, EPIDIVERSE will ensure the ESRs, and Europe, leading positions in this - emerging field. To explain the real-life relevance of epigenetics in natural systems, we will (1) develop genomic and bioinformatics tools for epigenomic analysis in natural settings; (2) determine natural epigenetic diversity, and its relationship - with environmental factors, in three common wild species across Europe; and (3) reveal the molecular mechanisms underlying natural epigenetic diversity through controlled experiments. This approach is innovative and timely because it integrates - several so far disconnected areas of epigenetic research, and it will transfer analytical methods from laboratory research to the real world. These are important steps forward if Europe wants to understand, manage, and possibly enhance plant - adaptability to pressing environmental challenges. - - 2021-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Netherlands - - - EPIDIVERSE - - - H2020-MSCA-ITN-2017 - - - 764965 - - - - - KOBENHAVNS UNIVERSITET - KOBENHAVNS UNIVERSITET - UNIVERSITY COLLEGE LONDON - DANMARKS TEKNISKE UNIVERSITET - - - EUR 2 500 000 - - - Generalised Entropy Models for Spatial Choices - - - EUR 2 574 486,25 - - - Denmark - Denmark - United Kingdom - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project will create a new category of models that can be used for describing a wide range of spatial choice problems in the social sciences. Spatial settings often have a very large number of choice alternatives. Discrete - choice models are used extensively to make counterfactual predictions based on observations of individual choices. Despite forty years of research, current spatial choice models still have two major generic short-comings that seriously limit their - ability to make counterfactual predictions. The new category of models will address these two short-comings. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Denmark - - - GEM - - - ERC-2016-ADG - - - 740369 - - - - - UNIVERSITAET BERN - UNIVERSITAET BERN - - - EUR 2 499 380 - - - Reconstruction of Pollinator-Mediated Speciation by Identification and Substitution of Causative Mutations - - - EUR 2 499 380 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - A central aim of contemporary research on the origin of species is to identify the genes that are functionally differentiated between nascent species. Understanding the molecular-genetic basis of speciation will answer - important questions that are of broad interest to geneticists, ecologists and evolutionary biologists. The RESPEC project will identify such “speciation genes”, map them onto conventional phylogenies and genetically reconstruct the process of - speciation. Pollinator-mediated speciation is an attractive system to achieve these goals. Speciation in Petunia is recent, ongoing and prezygotic. Shifts in pollination syndromes are complex but are composed of distinct traits that can be studied - individually. The advertising traits color and scent are known to be encoded by major effect genes, but for morphological traits no such information is available. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Switzerland - - - RESPEC - - - ERC-2016-ADG - - - 741354 - - - - - UNIVERSITAIR MEDISCH CENTRUM UTRECHT - UNIVERSITAIR MEDISCH CENTRUM UTRECHT - - - EUR 1 997 297,99 - - - Extracellular Vesicle-Inspired CArdiac Repair - - - EUR 1 997 297,99 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - More than 3.5 million people are newly diagnosed with heart failure every year in Europe with a long-term prognosis of 50% mortality within 4 years. There is a major need for more innovative, regenerative therapies that have - the potential to change the course of disease. My hypothesis is that we can recondition heart failure by stimulating cardiac repair with extracellular vesicles that are derived from progenitor cells. In my laboratory, extracellular released vesicles - containing a cocktail of stimulating factors, are amongst the most potent vectors for cardiac repair. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - EVICARE - - - ERC-2016-COG - - - 725229 - - - - - UNIVERSITAET BERN - - - EUR 187 419,60 - - - Maternal Enteric Microbiota for Offspring's Repertoire development and Illness Susceptibility - - - EUR 187 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - Recently, it has emerged that early life exposure to commensal microbes is crucial to instruct our immune system and prevent later life autoimmune and metabolic diseases. The host lab now showed that this education begins even - earlier – during gestation by signals from the maternal intestinal microbiota. Using the E. coli strain HA 107, genetically engineered to grow in vitro without the ability to persist in vivo, they demonstrated that transient intestinal colonisation - of pregnant germ-free mouse dams drives neonatal innate immune maturation. However, the long-term consequences of maternal microbiota cues especially for the adaptive immune system of the adult offspring remain elusive. - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - MEMORIS - - - H2020-MSCA-IF-2016 - - - 744257 - - - - - CONSIGLIO NAZIONALE DELLE RICERCHE - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSITY OF DURHAM - KEMIJSKI INSTITUT - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - Masarykova univerzita - POLITECNICO DI MILANO - UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN - ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA - UNIVERSITAT WIEN - ASTRAZENECA UK LIMITED - BASECLICK GMBH - DYNAMIC BIOSENSORS GMBH - - - EUR 3 827 591,28 - - - DNA as a training platform for photodynamic processes in soft materials - - - EUR 3 827 591,28 - - - Italy - France - United Kingdom - Slovenia - Germany - Czech Republic - Italy - Ireland - Italy - Austria - United Kingdom - Germany - Germany - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Light interaction with biomaterials is the driving mechanism of fundamental biological processes, from photosynthesis to DNA photodamage, and is a powerful tool in biomedicine for analytical, diagnostic and therapeutic - purposes. The main goal of LightDyNAmics is to achieve a complete understanding of the ultrafast dynamical processes at the molecular scale induced by UV light absorption in DNA, and to unveil the mechanisms leading to photodamage of the genetic - code. At the same time, our project will transfer this knowledge on light-matter interaction to a broad class of optoelectronic materials, highly relevant for Europe`s high-tech industries. - - 2022-03-31, Grant Agreement signed - - - 2018-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Italy - - - LightDyNAmics - - - H2020-MSCA-ITN-2017 - - - 765266 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 493 838,77 - - - Fundamental Understanding of Nanoparticle chemistry: towards the prediction of Particulate emissions and Material synthesis - - - EUR 1 493 838,77 - - - France - France - - - Research Organisations - Research Organisations - - While modern societies are facing urgent challenges related to reduction of particulate matter emissions from transportation engines, recent discoveries on the extraordinary properties of carbonaceous functional nanomaterials - have revealed opportunities associated with large-scale, flame-based synthesis of these otherwise unwanted combustion products. In both cases, our ability to study new, optimized solutions based on the specific industrial end-user needs is limited by - the absence of theoretical tools able to accurately predict the fluid dynamics and the chemistry involved in nanoparticle formation. Indeed, current knowledge on this fascinating but complex process is still rather incomplete. The proposed research - program, FUN-PM, will apply an innovative multi-disciplinary, multi-step approach in order to finally answer many unresolved kinetic questions concerning in particular: 1) formation and growth of molecular PAH precursors; 2) particle inception; 3) - subsequent particle growth and oxidation. Each single step will be experimentally isolated taking full advantage of complementary conventional shock tube techniques and up-to-date synchrotron-based detection technologies coupled to a newly - constructed high-rate repetition shock tube. If successful, the novel synchrotron-shock tube techniques will be utilized for the first time to obtain unique information on unknown key processes. The experimental results, with extensive theoretical - ab-initio calculations on relevant PAH reaction pathways, will constitute the base for the development of a comprehensive, detailed chemical kinetic model for particle chemistry applied to Real Fuels. Such model will improve the prediction - capabilities of current CFD codes for use in engine design, fuel reformulation, or industrial process optimization, with considerable benefits to the standards of living of European citizens, the environment, and the EU economy, towards the future of - clean transportations and novel nanomaterials. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - FUN-PM - - - ERC-2017-STG - - - 756785 - - - - - EUROPEAN MOLECULAR BIOLOGY LABORATORY - EUROPEAN MOLECULAR BIOLOGY LABORATORY - - - EUR 2 239 458 - - - Self-organisation across the scales in early mammalian development - - - EUR 2 239 458 - - - Germany - Germany - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - A defining feature of multi-cellular living systems is the capacity to break symmetry and generate patterns through self-organisation. Our project aims to understand the design principle of multi-cellular self-organisation, - using a well-suited model system: early mouse embryos. In mammals eggs lack polarity and symmetry is broken during early embryogenesis, which results in segregation of three cell lineages in the blastocyst. Progressive expansion and coalescence of - fluid-filled spaces form the blastocyst cavity that segregates the cavity-facing lineage from the rest. Despite extensive gene expression studies, how molecular and physical signals are dynamically coupled for self-organised blastocyst patterning - remains poorly understood. We aim to identify the mechanisms of feedback between cell polarity, mechanics (contractility, adhesion, pressure) and fate operating across sub-cellular to whole organismal scales. For this, we adopt a unique set of - strategies that integrate biology and physics: advanced live-imaging, quantification of molecular and physical parameters to integrate into lineage maps, reduced systems to establish physical models, and spatio-temporally controlled manipulations for - functional validation of those models. We will build up complexities. At the single-cell level, we will study de novo assembly of the apical domain in relation to cell contact and cortical contractility. For inside-outside patterning, we aim to - dissect the coordinated signalling between cell position and fate specification. Furthermore, we will study how fluid cavities, a yet unexplored parameter, contribute to cell sorting, apical polarisation and fate specification through generation of - pressure and contact-free cell surfaces. Ultimately, we will reconstitute embryogenesis in silico, reveal emerging properties and design engineer the blastocyst. In all, this study will set a paradigm for studying self-organisation on subcellular to - organismal scales. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - SelforganisingEmbryo - - - ERC-2016-ADG - - - 742732 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 497 547 - - - Structural and Functional Architectures of Multi-Kingdom Microbial Consortia Colonizing Plant Roots - - - EUR 1 497 547 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - The roots of healthy plants are colonized by a rich diversity of microbes, forming multi-kingdom microbial consortia that impact plant productivity. Despite the expected high connectivity between root microbiota members, our - understanding of microbe-microbe interactions in structuring microbial networks in plant roots as well as their functional impact on plant growth remains poorly understood. Based on recent findings in my group, I propose a conceptual framework aiming - at a functional understanding the holo-plant microbiome, where microbial interactions play an integral role in structuring root-associated microbial communities and maintaining microbiota balance and plant health. - - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - MICRORULES - - - ERC-2017-STG - - - 758003 - - - - - DOW CORNING EUROPE SA - UNIVERSITA DEGLI STUDI DI FERRARA - UNIVERSITE DE FRIBOURG - - - EUR 773 848,08 - - - Impact of air pollutants on cutaneous responses in both healthy and compromised skin barrier, and innovative solutions to protect skin against urban pollution - - - EUR 773 848,08 - - - Belgium - Italy - Switzerland - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Nowadays, our skin is increasingly more assaulted, as a result of the increasingly complexity of our living environment. Because of its critical location, the skin is continuously exposed not only to natural environmental - stress factors, such as UV radiation, ozone and extreme weather conditions associated with climatic changes, but also to pollutants/aggressors of anthropic origin, such as cigarette smoke and diesel/gasoline fuel exhaust. By combining the - complementary expertise of the three partners involved in the present consortium, i.e. polymer technology and formulation expertise (DCE), skin barrier understanding and biochemistry/molecular biology (UoF), and impact of diesel/gasoline exhaust on - cellular responses (UNIFR), this project will aim (i) at better understanding the consequences of air pollutants on both skin integrity and function, (ii) at investigating the synergistic effects of air pollutants such as ozone, cigarette smoke and - diesel exhaust with UV radiation, (iii) at discovering innovative solutions to protect skin against those environmental stressors using both a curative approach based on the optimization of the delivery and efficacy of antioxidant compounds, and a - preventive approach, based on the formation of a polymeric barrier film at the skin surface, (iv) at studying the impact of air pollutants on both healthy skin and compromised, damaged skin since the number of individuals suffering from skin diseases - such as atopic dermatitis and psoriasis continuously increases with the increasingly level of air pollution and air-conditioning systems. The variety of training offered under this EID proposal will enable three early-stage researchers to build - strong S&T background as well as to develop numerous transferable skills for their future career. The present training program will allow the researchers to expand their knowledge to new domains and applications, while also providing good - networking opportunities. - - 2021-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-EID - European Industrial Doctorates - - - Belgium - - - CITYCARE - - - H2020-MSCA-ITN-2017 - - - 765602 - - - - - UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6 - - - EUR 166 603,20 - - - Geometry of Nonnegative Rank - - - EUR 166 603,20 - - - France - - - Higher or Secondary Education Establishments - - This proposal is centered on nonnegative rank - a notion that modifies the definition of matrix rank. This project is basic research aimed to better understand the geometry of matrices and tensors of nonnegative rank at most - r, how this knowledge can be employed to improve exact and numerical nonnegative matrix algorithms, obtain an algorithm for nested polytopes in dimension three, and address questions about mixture models in statistics. Computing and understanding - nonnegative rank is truly interdisciplinary. Completing this project requires techniques from polyhedral geometry, real algebraic geometry, optimization, statistics, symbolic algebra, and numerics. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - France - - - NonnegativeRank - - - H2020-MSCA-IF-2016 - - - 748354 - - - - - FONDAZIONE TELETHON - THE UNIVERSITY OF EDINBURGH - UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II. - UNIVERSITE PARIS DIDEROT - PARIS 7 - Eidgenössische Technische Hochschule Zürich - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE - UNIVERSITY OF BRISTOL - - - EUR 2 975 345 - - - Control Engineering of Biological Systems for Reliable Synthetic Biology Applications - - - EUR 2 996 856,25 - - - Italy - United Kingdom - Italy - France - Switzerland - United Kingdom - France - United Kingdom - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - - Synthetic Biology aims at rational engineering of living organisms to improve human well-being and environmental sustainability, thus promising a paradigm shift in human technology. Its full potential has not been achieved yet - because of the complexity of engineering biological systems where basic biological parts are intrinsically noisy and not modular. The overarching goal of COSY-BIO is to develop a theoretical framework and innovative technological tools to engineer - reliable biological systems that are robust despite their individual components being not by translating principles of control engineering to molecular and cell biology. Automatic control is a well-established engineering discipline to build - “controllers” to steer the dynamic behaviour of a physical system in a desired fashion. By building upon control engineering for physical systems and by exploiting the unique features of living organisms, this project will identify generally - applicable approaches to design closed-loop feedback controllers for biological systems. To handle biological complexity, the project will explore three strategies of increasing difficulty “external” controllers, “embedded” controllers and - “multi-cellular” controllers. External controllers will be implemented in a computer acting on cells using small molecules via microfluidics devices. Embedded controllers will be made from biological parts and integrated within individual cells to - steer their behaviour. Multicellular controllers envisage two cell populations, one made up of cells with embedded controllers (controller cells) and the other will be the controlled population (target cells). In addition, a rapid prototyping - platform will enable to speed up the design-build-test cycles by means of optimal experimental design, microfluidics and cell-free systems. Proof-of-principles demonstrations in bacteria and yeast with relevance to biotechnology will be tackled to - prove the usefulness of this revolutionary technology. - - 2020-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-01-2016-2017 - FET-Open research and innovation actions - - - RIA - Research and Innovation action - - - Italy - - - COSY-BIO - - - H2020-FETOPEN-1-2016-2017 - - - 766840 - - - - - UNIVERSITY OF BRIGHTON - - - EUR 195 454,80 - - - Dual Function Polymer Materials for Blood Contacting Applications - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Surface-induced thrombosis and infection are two main complications which cause failure of medical devices. Device-related thrombosis is associated with activation of blood clotting and platelets adhesion and activation. - Infection of the implanted devices occurred as a result of bacteria adhesion to the biomaterial surface. A genuinely biocompatible polymer for blood-contacting devices should have both antithrombotic and antibacterial functionalities as both types of - complication lead to an increase in morbidity, extended hospital stay and mortality. - - 2019-09-17, ongoing project - - - 2017-09-18 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - United Kingdom - - - DualFun - - - H2020-MSCA-IF-2016 - - - 749207 - - - - - UNIVERZITET U NOVOM SADU FAKULTET TEHNICKIH NAUKA - University of Novi Sad Faculty of Sciences - Kreativno edukativni centar - VISOKA TEHNICKA SKOLA STRUKOVNIH STUDIJA U ZRENJANINU - Udruzenje naucnih komunikatora - CENTAR ZA PROMOCIJU NAUKE - - - EUR 98 000 - - - Friend to understand - - - EUR 112 700 - - - Serbia - Serbia - Serbia - Serbia - Serbia - Serbia - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - Our mission of exposing the researchers as ordinary people with an extraordinary job to the public at large in Serbia started in 2010. Annual impact assessment reports show that we significantly influenced the perception and - knowledge of the general public regarding WHAT the researchers do, but they also showed that there is room for improving the ways of showing WHO the researchers are, by making the personalities and faces of the researchers recognizable to the - society, as well as in clarifying WHY they become researchers, i.e. their motivation and inspiration to explain why research matters to society. Therefore, without losing a focus on WHAT, RN 2014-2015 will focus on the questions of WHO and WHY in - order to offer a new dimension of perceiving the researchers and offer more answers beyond the WHAT question. - - - 2015-12-31, closed project - - - 2014-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.5."> - - - MSCA-NIGHT-2014 - European Researchers' Night (NIGHT) - - - CSA - Coordination and support action - - - Serbia - - - Friend2U - - - H2020-MSCA-NIGHT-2014 - - - 633396 - - - - - UNIVERSITY OF BRADFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - TECHNISCHE UNIVERSITEIT DELFT - UNIVERSIDAD DE ZARAGOZA - JUSTUS-LIEBIG-UNIVERSITAET GIESSEN - BILKENT UNIVERSITESI VAKIF - UNIVERSITAET ULM - UNIVERSITY OF SOUTHAMPTON - UNIVERSITY OF NEWCASTLE UPON TYNE - - - EUR 2 834 979,84 - - - DyViTo: Dynamics in Vision and Touch - the look and feel of stuff - - - EUR 2 834 979,84 - - - United Kingdom - United Kingdom - Netherlands - Spain - Germany - Turkey - Germany - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Real world tasks as diverse as drinking tea or operating machines require us to integrate information across time and the senses rapidly and flexibly. Understanding how the human brain performs dynamic, multisensory - integration is a key challenge with important applications in creating digital and virtual environments. Communication, entertainment and commerce are increasingly reliant on ever more realistic and inmmersive virtual worlds that we can modify and - manipulate. Here we bring together multiple perspectives (psychology, computer science, physics, cognitive science and neuroscience) to address the central challenge of the perception of material and appearance in dynamic environments. Our goal is to - produce a step change in the industrial challenge of creating virtual objects that look, feel, move and change like ‘the real thing’. We will accomplish this through an integrated training programme that will produce a cohort of young researchers who - are able to fluidly translate between the fundamental neuro-cognitive mechanisms of object and material perception and diverse applications in virtual reality. The training environment will provide 11 ESRs with cutting-edge, multidisciplinary - projects, under the supervision of experts in visual and haptic perception, neuroimaging, modelling, material rendering and lighting design. This will provide perceptually-driven advances in graphical rendering and lighting technology for dynamic - interaction with complex materials (WP1-3). Central to the fulfillment of the network is the involvement of secondments to industrial and public outreach partners. Thus, we aim to produce a new generation of researchers who advance our understanding - of the ‘look and feel’ of real and virtual objects in a seamlessly multidisciplinary way. Their experience of translating back and forth between sectors and countries will provide Europe with key innovators in the developing field of visual-haptic - technologies. - - 2021-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - DyViTo - - - H2020-MSCA-ITN-2017 - - - 765121 - - - - - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - - - EUR 1 982 925 - - - mechanical BEhavior of Fluid-INduced Earthquakes - - - EUR 1 982 925 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Fluids play an important role in fault zone and in earthquakes generation. Fluid pressure reduces the normal effective stress, lowering the frictional strength of the fault, potentially triggering earthquake ruptures. Fluid - injection induced earthquakes (FIE) are direct evidence of the effect of fluid pressure on the fault strength. In addition, natural earthquake sequences are often associated with high fluid pressures at seismogenic depths. Although simple in theory, - the mechanisms that govern the nucleation, propagation and recurrence of FIEs are poorly constrained, and our ability to assess the seismic hazard that is associated with natural and induced events remains limited. This project aims to enhance our - knowledge of FIE mechanisms over entire seismic cycles through multidisciplinary approaches, including the following: - - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Switzerland - - - BEFINE - - - ERC-2017-STG - - - 757290 - - - - - PRINS LEOPOLD INSTITUUT VOOR TROPISCHE GENEESKUNDE - PRINS LEOPOLD INSTITUUT VOOR TROPISCHE GENEESKUNDE - MEDICAL RESEARCH COUNCIL - UNIVERSITE CATHOLIQUE DE LOUVAIN - DALBERG DATA INSIGHTS - - - EUR 149 783 - - - Enhanced Place Finding (EPF) of TB transmission hotspots - - - EUR 149 783 - - - Belgium - Belgium - United Kingdom - Belgium - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - TB is transmitted via person-to-person aerosols. Recent studies suggests that in TB endemic areas up to 70% of transmission events take place outside the household in public places. Moreover, TB transmission is unequally - spatially distributed and occurs in transmission hotspot areas. Mathematical models consequently demonstrated that identifying hotspots and blocking within-hotspot-transmission through targeted public health interventions will be the most efficient - way of lowering the TB burden. In the present PoC proposal we aim to complement the population-based Enhanced-Case-Finding intervention tested in the INTERRUPTB study, with a spatially more targeted “Enhanced-Place-Finding” (EPF) approach to identify - transmission hotspots in an unbiased fashion. Using traditional methods to find transmission hotspots can only be done retrospectively after years of data collection. Therefore we propose a novel EPF strategy to detect transmission hotspots in - real-time using phone-tracking technology to establish a spatial map of aggregated TB patients movements. Within the ERC-funded INTERRUPTB study in The Gambia, we sequenced 2000 mycobacterial isolates, which allows us to establish a bacterial genetic - transmission network. Within the PoC proposal, we seek to reconsent these patients to analyze their everyday movements using classical contact investigation complemented by phone tracking, to determine which public places have an increased risk of TB - transmission. We aim to demonstrate that phone tracking of TB patients can be a cheap, easy, and, most importantly, prospective TB transmission hotspots identification tool, no longer requiring molecular epidemiological investigations. Such a finding - can ultimately be developed into an app that warns national TB programs of early TB outbreaks, so that early public health measures like increased ventilation and active case finding can be initiated. This approach can furthermore be applied to other - infectious diseases. - - 2019-02-28, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Belgium - - - TB-EPF - - - ERC-2016-PoC - - - 727695 - - - - - UNIVERSITE DE NEUCHATEL - UNIVERSITE DE NEUCHATEL - - - EUR 1 997 675 - - - Towards a decentred history of the Middle East: Transborder spaces, circulations, frontier effects and state formation, 1920-1946 - - - EUR 1 997 675 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - While the crisis of the territorial nation-state in the Middle East has once again been brought to a head by the wars in Iraq and Syria, it cannot be simply understood as the logical consequence of an imported political - construction. Based on two epistemological notions – borderlands as histoire-problème (history-as-problem) and the co-production of borders between state and society – this research project proposes to rethink the classical historical narrative about - the emergence of the post-Ottoman Middle East. Taking its cue from trans-border phenomena and thus paying attention to the circulation of people, goods and ideas as well as to everyday encounters between local actors and state representatives, the - project will be guided by four principle objectives to offer: - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Switzerland - - - BORDER - - - ERC-2016-COG - - - 725269 - - - - - WAGENINGEN UNIVERSITY - UNIVERSITAET BREMEN - RIJKSUNIVERSITEIT GRONINGEN - INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE - INSTITUTO VALENCIANO DE INVESTIGACIONES AGRARIAS - Biologicke centrum AV CR, v. v. i. - KOPPERT BV - FOOD AND AGRICULTURE ORGANIZATION OF THE UNITED NATIONS FAO - CAB INTERNATIONAL - VETERINAERMEDIZINISCHE UNIVERSITAET WIEN - - - EUR 3 288 069 - - - Breeding Invertebrates for Next Generation BioControl (BINGO) - - - EUR 3 288 069 - - - Netherlands - Germany - Netherlands - France - Spain - Czech Republic - Netherlands - Italy - United Kingdom - Austria - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - - BACKGROUND - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Netherlands - - - BINGO - - - H2020-MSCA-ITN-2014 - - - 641456 - - - - - KEYGENE NV - - - EUR 177 598,80 - - - Aeroponic Inulin and Rubber - - - EUR 177 598,80 - - - Netherlands - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Natural rubber is an essential commodity for the European society. However, the natural rubber market is seriously endangered. Finding an alternative rubber source for the rubber tree is an urgent issue for EU. The EU has - funded several projects on alternative rubber crops in the past. Taraxacum koksaghyz (TKS) was identified as the most promising alternative. However, this wild plant is small and does not produce sufficient rubber to be economically profitable. - Rubber production can be increased by plant breeding and by improving the growing conditions. - - 2020-02-29, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-SE - Society and Enterprise panel - - - Netherlands - - - AIR - - - H2020-MSCA-IF-2016 - - - 752921 - - - - - UNIVERSIDAD AUTONOMA DE MADRID - UNIVERSIDAD AUTONOMA DE MADRID - - - EUR 150 000 - - - Imaging-XChem: A computational package for ultrafast electronic control in chemistry - - - EUR 150 000 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Commercial quantum-chemistry computational packages are widely used in science and chemical industry to predict the properties and reactivity of molecules and to design new compounds and drugs that can eventually be - synthesized in the laboratory. The software developed in the framework of the ERC AdG project XCHEM is aimed at providing a full quantum mechanical description of a large variety of chemical processes that cannot be addressed by standard quantum - chemistry packages, namely those processes in which molecular ionization takes place. An accurate description of molecular ionization is crucial to develop new applications and make reliable predictions in emerging scientific disciplines, such as - attochemistry, single-molecule imaging, and coherent attosecond control of chemical reactions. - - - 2019-04-30, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Spain - - - Imaging-XChem - - - ERC-2017-PoC - - - 780284 - - - - - HUMANITAS UNIVERSITY - - - EUR 262 269 - - - Circadian Control of Histone Methylation Dynamics through the Fine-tuning of Methionine Metabolic Flux - - - EUR 262 269 - - - Italy - - - Higher or Secondary Education Establishments - - The circadian clock directs almost all aspects of diurnal physiology, including metabolism. Defects in circadian rhythms influence physiology and behavior with implications for numerous pathological conditions, including - cancer, metabolic syndrome, obesity, diabetes and cardiovascular diseases. By controlling metabolic homeostasis at the cellular level, the clock can directly influence cellular regulatory networks, including those that govern chromatin dynamics. The - goal of this proposal is to investigate if metabolic pathways able to influence gene expression via chromatin dynamics are under circadian control and whether these regulatory networks are crucial for the maintenance of a correct metabolic - homeostasis. We will test if the clock governs the “methylation potential” of the cell by regulating the diurnal expression of rate-limiting enzymes of methionine metabolism. By using metabolite restriction, pharmacological and gene editing - approaches we will disrupt circadian rhythmicity of SAM and SAH. We will then use state-of-the-art methods including, transcriptomics, epigenomics and metabolomics to investigate the impact of this regulatory network on circadian transcriptional - regulation, histone methylation dynamics and metabolic homeostasis. By dissecting how circadian regulation, metabolism and epigenetics are interconnected we will gain novel insights into how these factors contribute to normal physiology and disease. - - 2020-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Italy - - - MetEpiClock - - - H2020-MSCA-IF-2016 - - - 749869 - - - - - FREIE UNIVERSITAET BERLIN - FREIE UNIVERSITAET BERLIN - - - EUR 1 373 022 - - - Protest and Order. Democratic theory, contentious politics, and the changing shape of western democracies - - - EUR 1 373 022 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The research project aims to analyze the interrelationship between protest and political order under the contextual conditions of the changing shape of modern western democracy. Two groups of ques-tions are connected to this - study perspective, which will be answered by means of a democratic-theoretically-led synchronous comparison of selected contemporary protest movements – anonymous digi-tal protest movements, transnationally organized alter-globalization protest - movements, the No Border movement and the rightwing identitarian protest movement: The aim is to clarify firstly (1) the extent to which the new forms of protest question the premises of democratic orders, what potential for further de-velopment lies - within the new forms of protest on the one hand, and what are the challenges to democracy on the other. Secondly, the aim is to determine (2) the influence and relevance held by the democratic order itself in an age of the changing shape of democracy - with regard to the specific formation of the new forms of protest, and what statements can be made on how the formation of the order is changed, in turn, by the new forms of protest themselves. In order to achieve these study perspectives, POWDER - consists of an overarching democratic-theoretical framework project (TFP) and four empirical subprojects (SP 1-4), which each analyze one of the protest movements mentioned in the context of a qualitative approach (documentary analysis, participatory - observation, qualitative interviews). The comparison of these protest movements investigates (I) recurring patterns, but also contrasting assessments with regard to the interre-lationship between the political order and the protest movements, - examines at a second level (II) the dif-ferent manners in which the new forms of protest challenge democratic-theoretical dimensions, and at-tempts at the third level (III) to reconstruct a general democratic-theoretical determination of meaning of - present-day protest movements. - - 2023-03-31, Grant Agreement signed - - - 2018-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - POWDER - - - ERC-2017-STG - - - 757452 - - - - - EBERHARD KARLS UNIVERSITAET TUEBINGEN - EBERHARD KARLS UNIVERSITAET TUEBINGEN - - - EUR 1 498 216 - - - Chromatin Packing and Architectural Proteins in Plants - - - EUR 1 498 216 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The three-dimensional organization of the genome, which strikingly correlates with gene activity, is critical for many cellular processes. The evolution of molecular techniques has allowed us to unveil chromatin structure at - an unprecedented resolution. The most intriguing chromatin structures observed in animals are TADs (Topologically Associating Domains), which represent the functional and structural chromatin domains demarcating the genome. Structural proteins such - as insulators proteins, on the other hand, have been shown to play crucial roles in mediating the formation of TADs. However, major structural factors relevant to chromatin structure are still waiting to be discovered in land plants. My preliminary - work shows that TADs are widely distributed across the rice genome, and motif sequence analysis suggests the enrichment of plant-specific transcription factors at TAD boundaries, which jointly give rise to an exciting hypothesis that these proteins - might be the long-sought-after insulators in land plants. By using various state-of-the-art molecular and computational tools, this timely project aims to fill a huge gap in plant functional genomics and substantially advance our understanding of - three-dimensional chromatin structure. This project consists four major aims, which collectively will uncover the identities of plant insulator proteins and generate insights into the dynamics of structural chromatin domains during stress adaptation. - Aim 1 will identify and characterize the stability and plasticity of functional chromatin domains in the rice genome during temperature stress adaptation. Aim 2 will identify insulator elements and other structural features of chromatin packing in - the Marchantia polymorpha genome from a structural genomics approach. Aim 3 will establish the role of candidate proteins as plant insulators. Lastly, Aim 4 will generate functional insights into the molecular mechanism by which plant insulators - shape the three-dimensional genome. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - CHROMATADS - - - ERC-2017-STG - - - 757600 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 484 688 - - - Comet and Asteroid Re-Shaping through Activity - - - EUR 1 484 688 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - The proposed project will significantly improve the insight in the processes that have changed a comet nucleus or asteroid since their formation. These processes typically go along with activity, the observable release of gas - and/or dust. Understanding the evolutionary processes of comets and asteroids will allow us to answer the crucial question which aspects of these present-day bodies still provide essential clues to their formation in the protoplanetary disc of the - early solar system. - - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - CAstRA - - - ERC-2017-STG - - - 757390 - - - - - UNIVERSITAETSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITAET MAINZ - UNIVERSITAETSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITAET MAINZ - - - EUR 150 000 - - - Bifunctional and regeneratively active biomaterial: Towards an ultimate solution for osteoarthritis treatment - - - EUR 150 000 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Osteoarthritis (OA) is the most common form of arthritis of the joints, affecting over 70 million EU citizens. At present, no cure for OA is available; only symptomatic therapies may help to ameliorate this painful disorder. - OA affects the integrity of the cartilage and progresses to an increased damage in its surrounding tissues, inclusive bone, and to inflammation of the synovial tissue. The latter reaction is caused by an accumulation of bone splinters. The therapy of - choice would be – if available – bidirectional: first, regeneration of the damaged cartilage (by implants) and second, dissolution of the bone fragments (by injections). This proposal presents for the first time this two-fold solution. - - - 2019-02-28, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Germany - - - ArthroDUR - - - ERC-2017-PoC - - - 767234 - - - - - TECHNISCHE UNIVERSITEIT DELFT - TECHNISCHE UNIVERSITEIT DELFT - - - EUR 1 499 941 - - - SCHEDULING OF EVENT-TRIGGERED CONTROL TASKS - - - EUR 1 499 941 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The advances in electronic communication and computation have enabled the ubiquity of Cyber-Physical Systems (CPS): digital systems that regulate and control all sorts of physical processes, such as chemical reactors, water - distribution and power networks. These systems require the timely communication of sensor measurements and control actions to provide their prescribed functionalities. Event-triggered control (ETC) techniques, which communicate only when needed to - enforce performance, have attracted attention as a mean to reduce the communication traffic and save energy on (wireless) networked control systems (NCS). However, despite ETC’s great communication reductions, the scheduling of the aperiodic and - largely unpredictable traffic that ETC generates remains widely unaddressed – hindering its true potential for energy and bandwidth savings. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - SENTIENT - - - ERC-2017-STG - - - 755953 - - - - - CENTRO INTERNAZIONALE DI ALTISTUDI AGRONOMICI MEDITERRANEI - CONSIGLIO NAZIONALE DELLE RICERCHE - UNIVERSITA DEGLI STUDI DI BARI ALDO MORO - CENTRO DI RICERCA, SPERIMENTAZIONE E FORMAZIONE IN AGRICOLTURA BASILE CARAMIA - INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - INSTITUTO VALENCIANO DE INVESTIGACIONES AGRARIAS - UNIVERSITE CATHOLIQUE DE LOUVAIN - NATURAL ENVIRONMENT RESEARCH COUNCIL - RUSSELL IPM LTD - BENAKI PHYTOPATHOLOGICAL INSTITUTE - MEDITERRANEAN AGRONOMIC INSTITUTE OF CHANIA - INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE DE TUNISIE - - - EUR 1 777 500 - - - Capacity Building And Raising Awareness In Europe And In Third Countries To Cope With Xylella fastidiosa - - - EUR 1 777 500 - - - Italy - Italy - Italy - Italy - France - Spain - Spain - Belgium - United Kingdom - United Kingdom - Greece - Greece - Tunisia - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Other - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - - CURE-FX aims to establish a multidisciplinary research program to answer the urgent need to improve prevention, early detection and control of Xylella fastidiosa (Xf). An appropriate approach to this emergency should include a - coordination and multidisciplinary interaction between a plurality of competences and it can be facilitated by a more intense exchange and mobility of researchers.The objectives of CURE-FX are: To exchange the scientific capacities and novelties - among the European Countries as well as between EU and third countries, in particular sensitive neighbor countries. To strengthen the knowledge and the know-how on Xf in third countries having intense exchange of plant material with Europe. To raise - awareness in relation to Xf. These objectives will be acheived through: Strengthen preventive measures by consolidating expertise and awareness of plant health agencies, decision-makers and relevant stakeholders; Analyze Xf-hosts interaction and - epidemiology; Develop advanced diagnostic tools for the detection and characterization of Xf and associated vectors; Consolidate innovative approaches for disease prevention, monitoring and control; Improving pest risk analysis, phytosanitary - legislations and contingency measures for a safe plant material trade and Integrating with current platforms for adequate communication and dissemination ensuring an effective knowledge transfer among the various actors involved. The proposal - involves partners from the following countries: Italy, France, Greece, Spain, Belgium, UK, Egypt, Morocco, Tunisia, Lebanon and Iran. Partner countries selected are differently involved in the study and management of quarantine pests, although each - one with a different role, approach and competence. These countries can be divided into two groups: Group 1: countries where the disease is already present (Italy, France, Iran); Group 2: the other countries where the disease is currently absent, but - the risk of its introduction is high - - 2021-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Italy - - - CURE-XF - - - H2020-MSCA-RISE-2016 - - - 734353 - - - - - INSTITUTO DE CIENCIAS SOCIAIS - - - EUR 148 635,60 - - - Uncertain Power: Representing the king in the Portuguese empire (1640-1750) - - - EUR 148 635,60 - - - Portugal - - - Higher or Secondary Education Establishments - - This project aims at analysing the authority of the viceroys and governors-general - the highest representatives of the Portuguese kings – in the States of India and Brazil between 1640 and 1750 and as such, it deals with the - relevance of non-formal expressions of power and authority, and their role in the efficiency of political communication. UNCERTAINPOWER seeks early expressions of the combination between formal and non-formal expressions of power and authority, - namely in places where the physical presence of the main decision-makers was impossible to happen. In a world with ever-changing systems of communication, where virtual forms of power become more and more present, to offer a diachronic perspective on - the uncertainties that long-distance expressions of power entail is relevant. The choice of the early-modern Portuguese empire is related with its early presence in the four parts of the world in a period when technologies of power and of - communication were very different from ours. In UNCERTAINPOWER, issues that are still relevant today, such as the ways of expressing authority in very different socio-cultural contexts, the reception of this authority, as well as the links between - these processes and the conservation of society will be discussed. Which were the ways chosen by Portuguese viceroys and governors to communicate their power and authority with the societies under their control? How did these royal agents exercise - the prerogative of representing the royal power in an empire with a significant territorial extension and with a plurality of cultural and political realities? How did they adjust their political cultures to the local needs? How did the local - contexts influence their ways of governing? And how did mobility challenge the meanings of power and authority? The more tangible outcomes of this project include 6 articles, 1 book and a virtual exhibition. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Portugal - - - UNCERTAINPOWER - - - H2020-MSCA-IF-2016 - - - 749427 - - - - - ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM - ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM - - - EUR 2 251 719 - - - DNA Damage and Repair and its Impact on Healthy Ageing - - - EUR 2 251 719 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - We pioneered an initially highly controversial connection between DNA damage and (accelerated) aging. In the previous ERC grant ‘DamAge’ we reached the stage that (segmental) aging in DNA repair-deficient mice can be largely - controlled. The severity of the repair defect determines the rate of segmental aging; the repair pathways affected influence which organs age fast; conditional repair mutants allow targeting accelerated aging to any organ. Importantly, we found that - dietary restriction (DR), the only universal intervention known to delay aging, extends remaining life- and healthspan in progeroid Ercc1Δ/- mutants by 200% (see Vermeij et al., Nature 2016 and fig.2). Also Xpg-/- progeroid repair mice strongly - benefit from DR, generalizing this finding. The prominent Alzheimer- and Parkinson-like neurodegeneration is even retarded up to 30-fold(!) disclosing powerful untapped reserves unleashed by 30% less food, with enormous clinical potential. Also we - discovered that in accelerated and normal aging gene expression declines due to accumulating stochastic transcription-blocking lesions and that DR counteracts genomic dysfunction. In Dam2Age we will focus on the cross-talk between DNA damage, aging - and DR with emphasis on the relevance for normal aging, elucidate underlying mechanisms and use our unique -for DR research superior- mouse models and a variety of novel assays to search for effective nutritional-pharmacological DR mimetics. This - serves as a stepping stone towards potent universal therapy for a range of repair-deficient progeroid syndromes and prevention of many aging-related diseases, most urgently dementia’s, to promote sustained health. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Netherlands - - - Dam2Age - - - ERC-2016-ADG - - - 742426 - - - - - GOETEBORGS UNIVERSITET - - - EUR 173 857,20 - - - The Role of Neuroinflammation in Alzheimer’s Disease - - - EUR 173 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - Alzheimer’s disease (AD) is a major public health problem with substantial economical and social impacts worldwide. Despite intense research, the pathological mechanisms of AD are still unclear. Under homeostasis, a delicate - balance is struck between disposal of pathogenic proteins by the brain’s immune cells, microglia, and the inflammation produced by these cells. Indeed, during an acute activation, microglia are protective, but if microglia enter an over-activated - state they can induce chronic inflammation through oxidative stress that in turn leads to neuronal damage. Thus, gaining data on the chain of events involved in microglial action is a prerequisite to understanding AD. This project is a large - interdisciplinary collaborative effort involving well-established methods such as confocal imaging and transgenic zebrafish, with newly developed photopharmacological tools. Drs Kettunen, Grøtli and Andréasson provide the world-leading expertise - required for the project. By coordinating this project, Dr Mourabit will gain invaluable experience in biomedical research, photochemistry, project management, supervision, and the production of scientific results. The novel photoresponsive probes - used here will allow for photonic in vivo de/activation of microglia, generating new information on their spatiotemporal activity, in real-time. This state-of-the-art resolution of cell-tracking and control of microglial signalling will provide - innovative data on the pathology of neuroinflammation. We believe this interdisciplinary team will push the boundaries of research in AD. This project has the potential to identify new treatments for AD, and influence the direction of neurobiology. - This project will create a unique career opportunity for Dr Mourabit, enabling him to crossover from an environmental background to biomedical research. The marrying of such interconnected disciplines will help Dr Mourabit set the foundations of an - eclectic and vibrant research group. - - 2019-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - INFLAMM-ALZ - - - H2020-MSCA-IF-2016 - - - 750403 - - - - - DANMARKS TEKNISKE UNIVERSITET - ALBERT-LUDWIGS-UNIVERSITAET FREIBURG - LUNDS UNIVERSITET - FUNDACAO CALOUSTE GULBENKIAN - ARCTICMASS EHF - - - EUR 1 559 675,88 - - - Advanced use of mosses for biotechnological solutions - - - EUR 1 559 675,88 - - - Denmark - Germany - Sweden - Portugal - Iceland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - MossTech will expand the tools for green biotechnology. By using the simplest land plants, the mosses, MossTech will develop new green cell factories for the production of proteins, lipids and fine chemicals. MossTech will - train 6 highly qualified ESRs in modern biotechnology with the focus on expanding the use of green cells in biotechnological applications. The consortium of three universities, one research institution and four companies together provides a strong - background for training in scientific and transferable skills. - - - 2021-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-EID - European Industrial Doctorates - - - Denmark - - - MossTech - - - H2020-MSCA-ITN-2017 - - - 765115 - - - - - DUBLIN CITY UNIVERSITY - FH OO FORSCHUNGS & ENTWICKLUNGS GMBH - LINNEUNIVERSITETET - TECHNISCHE UNIVERSITEIT EINDHOVEN - UNIVERSITAT LINZ - AWS-INSTITUT FUR DIGITALE PRODUKTEUND PROZESSE GGMBH - RAIFFEISENLANDESBANK OBEROSTERREICHAG - - - EUR 3 869 128,44 - - - Pioneering the Digital Future for Omnichannel Retail Managers - - - EUR 3 869 128,44 - - - Ireland - Austria - Sweden - Netherlands - Austria - Germany - Austria - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The overall goal of PERFORM is to establish a European training network to prepare the next generation of Digital Retail Managers. Established Business Models need to be revised as customer behaviour is changing. Customers no - longer prefer online or instore purchasing but switch between channels to suit their own personal requirements. Innovative digital technologies such as Internet of Things, Big Data, advanced analytics as well as augmented reality novel payment - systems and visualisation concepts can create a unique and individual customer experience. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Ireland - - - PERFORM - - - H2020-MSCA-ITN-2017 - - - 765395 - - - - - UNIVERSITETET I TROMSOE - MATIS OHF - HASKOLI ISLANDS - UNIVERSITEIT UTRECHT - THE MANCHESTER METROPOLITAN UNIVERSITY - CENTRO TECNOLOGICO DEL MAR - FUNDACION CETMAR - MAPIX TECHNOLOGIES LTD - SYNTESA APS - - - EUR 2 724 033,96 - - - Social Science Aspects of Fisheries for the 21st Century - - - EUR 2 724 033,96 - - - Norway - Iceland - Iceland - Netherlands - United Kingdom - Spain - United Kingdom - Denmark - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - SAF21 is an interdisciplinary and intersectoral network that embeds the social scientists of the future into EU fisheries management systems. It trains experts in analysis of human social behaviour for the better management of - socio-ecological complex systems such as fisheries. Behaviour of fishers is complex as trust building and norms acceptance influence compliance with fishing regulations in unpredictable ways. The desired behaviour of fishers is often different from - the actual subsequent one as those involved adapt to and find ways around new regulatory regimes, often with catastrophic consequences on resources. Therefore, an integrated understanding of the fine mechanisms governing fishers’ behaviour in - relation with the regulative processes is needed, to the benefit of decision makers, fishing industry and the environment alike. Academic research and training have insufficiently reflected this need. SAF21 will contribute to rectifying this by - training researchers in using tools of the 21st century, e.g. computational sociology techniques, to analyse this topic from a multitude of angles: public understanding of fisheries, trust and norms, social and regulative norms, social marketing of - fisheries norms, stakeholders interaction in different management systems and socio-economic resilience. This knowledge will initiate the development of innovative management strategies, especially when it comes to shifting to new regulatory regimes. - The wide-ranging training envisaged will offer a structured doctoral training in academic and transferable skills in addition to highly intersectoral non-academic mobility opportunities. Thus, the SAF21 candidates will have the necessary skills and - experience to cross disciplines and work sectors. SAF21 will provide researchers the opportunity to fulfill their scientific social responsibility at a higher level than conventional doctoral programs, by ensuring significant time and training for - public engagement and outreach. - - 2018-12-31, ongoing project | - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Norway - - - SAF21 - - - H2020-MSCA-ITN-2014 - - - 642080 - - - - - UNIVERSITAT ZURICH - UNIVERSITAT ZURICH - - - EUR 1 362 401 - - - New paradigms for correlated quantum matter:Hierarchical topology, Kondo topological metals, and deep learning - - - EUR 1 362 401 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Discovering, classifying and understanding phases of quantum matter is a core goal of condensed matter physics. Next to the notion of symmetry breaking phases, the concept of topological phases of matter is a prevailing theme - of recent research. Topological phases are envisioned for various applications due to their universal and robust properties, such as protected conducting boundary modes, and provoke fundamental questions about the nature of many-body quantum states - by providing the basis for exotic quasiparticles. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Switzerland - - - PARATOP - - - ERC-2017-STG - - - 757867 - - - - - UNIVERSITY OF LEICESTER - WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - RIJKSUNIVERSITEIT GRONINGEN - BAYERISCHE JULIUS-MAXIMILIANS UNIVERSITAT WURZBURG - Biologicke centrum AV CR, v. v. i. - UNIVERSITY OF HAIFA - UNIVERSITAT DE VALENCIA - UNIVERSITA DEGLI STUDI DI PADOVA - UNIWERSYTET JAGIELLONSKI - THE HEBREW UNIVERSITY OF JERUSALEM - - - EUR 3 809 005,92 - - - Comparative INsect CHRONobiology - - - EUR 3 809 005,92 - - - United Kingdom - Germany - France - Netherlands - Germany - Czech Republic - Israel - Spain - Italy - Poland - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Chronobiology is the study of biological rhythms. The best understood cycles are those with circadian 24 hour periods that modulate the temporal dynamics of physiology and behaviour of all higher organisms. Four model - organisms have been widely used to study the underlying molecular biology of endogenous circadian clocks, Cyanobacteria, the fungus Neurospora, the fruitfly Drosophila, and the mouse. Insect clocks, both circadian and seasonal, are vital for - adaptation to the environment and recent global patterns of climate change mean that insect pests and vectors of disease are expanding their ranges into Europe. Consequently there is an urgent need to study the circadian clocks of these insects and - how they synchronise to the environment. CINCHRON will create an integrated European centre of excellence for the research training of ESRs in the emerging multidisciplinary field of Comparative INsect CHRONobiology. CINCHRON will bring together - molecular neurogeneticists working predominantly with Drosophila, and comparative biologists who study circadian and seasonal clocks of non-model insects of economic importance. These researchers have different approaches so we will harness their - different skills for mutual benefit via the integrated training of their ESRs in association with industrial partners. This will be done by high level interactions between university and industry, as well as interactions among laboratories with - different areas of expertise, thereby connecting the different sectors (academic and commercial) as well as different disciplines. The goal is to seed-corn the next generation of researchers with highly trained, flexible workers in cutting edge - technological methods and complementary generic skills that will support European academic, academic-related and industrial institutions. CINCHRON will therefore contribute to the integration and cohesion of future European research efforts in - solving pure and applied biological problem. - - 2022-05-31, Grant Agreement signed - - - 2018-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - CINCHRON - - - H2020-MSCA-ITN-2017 - - - 765937 - - - - - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - - - EUR 2 499 333 - - - Human interaction and the evolution of spoken accent - - - EUR 2 499 333 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - If a group of people were stranded on a desert island with limited contact to outside communities for a period of time, then the group would develop its own characteristic way of speaking or spoken accent. A lack of suitable - data as input to an evolutionary computational model has meant that we have but a poor understanding of how spoken accent emerges out of human interaction. Yet a breakthrough in this area is critical for explaining the various forces - including - contact between individuals through increased migration - that shape spoken accent development ultimately leading to language diversification and change. The project remedies this deficiency by developing a model of how random, local interactions - between individuals leading to group-specific spoken accents can push the sound patterns of languages between stable and changing states. The methodological innovation is that the model's predictions of how spoken accent evolves will be constrained - by longitudinal observations about how it actually develops within a group of speakers over time. We seek to generalise from diverse types of data: from children growing up in remote rural communities as opposed to high-contact urban settings; from - languages that differ markedly in their sound structure; and from groups of adults isolated together for several months during an Antarctic winter. The project's scientific impact is on developing a computational framework for unifying historical - sound change with the cognitive mechanisms by which speech is communicated and adapted to different social settings. The further impact is on understanding how migration and exposure to other accents change the sounds of language. The long-term - significance of the project is to build a computationally predictive model of the way that microscopic idiosyncrasies in how humans process speech in everyday conversations accumulate into group-level macroscopic spoken accent change leading to - language diversification. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - InterAccent - - - ERC-2016-ADG - - - 742289 - - - - - UNIVERSITE DE GENEVE - UNIVERSITE DE GENEVE - - - EUR 2 497 525 - - - Unequal Democracies - - - EUR 2 497 525 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The proposed research program explores the implications of rising income inequality for the political process in advanced democracies and for the policies produced by competition among political parties and organized - interests. The program posits that the political implications of inequality operates through two channels: inequality influences what citizens want from government, but it also affects political participation and influence and hence, by extension, - government responsiveness to the preferences of different citizens. Students of the politics of inequality have tended to focus on only one channel, to the neglect of the other. The fundamental objective of the proposed research program is to develop - a unified framework that draws on both research traditions and, in so doing, addresses lacunae in each. Another objective is to explore how the political consequences of low-end inequality (growing separation of the poor from the middle class) differ - from the political consequences of high-end inequality (the growing concentration of income at the very top of the income distribution). The core questions that animate the research program are “macro” questions, pertaining processes and outcomes - that are observed at the country level (or, in other words, the political-system level), but these questions will be addressed, in part, through analyses of individual attitudes, preferences and behavior. The latter analyses will involve a couple of - original surveys, including a survey of attitudes towards the rich, as well as the use of existing national and cross-national survey data. With respect to macro-level comparisons, the research program will emphasize changes over time: changes in the - structure of inequality as well as the level of inequality, changes in preferences and coalitions among citizens and organized interests and, finally, changes in income (or class) bias in democratic representation. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Switzerland - - - UneqDems - - - ERC-2016-ADG - - - 741538 - - - - - IDRYMA IATROVIOLOGIKON EREUNON AKADEMIAS ATHINON - IDRYMA IATROVIOLOGIKON EREUNON AKADEMIAS ATHINON - - - EUR 2 355 000 - - - PRECISION CARE IN SYSTEMIC AUTOIMMUNITY: AN INTEGRATED MULTI-TISSUE/LEVEL APPROACH FOR SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) - - - EUR 2 355 000 - - - Greece - Greece - - - Research Organisations - Research Organisations - - Systemic lupus erythematosus (SLE) is a heterogeneous disease whereby an interplay of environmental, genetic and epigenetic factors lead to perturbation of complex biological networks culminating into diverse clinical - phenotypes of varying severity. High throughput methods have allowed an “initial glimpse” into pathogenesis and have laid the foundations for a molecular-based taxonomy for personalized therapy. Based on our experience with the molecular - characterization of SLE, a recently completed RNA sequencing analysis of 150 patients, and our track- record of “paradigm shift” trials in SLE, we will integrate data from multi-tissue analyses with novel technologies to improve its diagnosis, - monitoring and therapy, and ask fundamental pathogenetic questions in systemic autoimmunity. More specifically, we will design gene expression panels and “expression profile”/”clinical trait” correlation matrices for diagnostics, personalized - immunotherapy and improved clinical trial design. In a systematic multi-tissue approach, we will examine the role of somatic mutations in enhancing immune hyperactivity and the risk for lymphoma. The staggering (7-9:1) female predominance will be - elucidated through elaborate genomic, epigenomic and microbiota analyses of family trios. Finally, we will be pursuing the innovative hypothesis that the fundamental abnormalities of SLE lie within the bone marrow hematopoietic stem cells (HSCs) - - from which all cells that participate in the pathogenesis of SLE originate - and establish it as a unifying pathogenetic mechanism. By a combination of novel experimental analyses with single cell genomics, multi–omics, humanized animal models, - genome editing and an “organ on-a-chip” device, we will validate HSCs as a therapeutic target. The utility of SLE research extends beyond its boundaries, by providing unique insights as to how the immune system recognizes self-constituents and - maintains its homeostasis, and how gender impacts on disease biology. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Greece - - - LUPUSCARE - - - ERC-2016-ADG - - - 742390 - - - - - GOETEBORGS UNIVERSITET - - - EUR 247 059 - - - The microbial degradation and utilization of mucin by Bacteroides in ulcerative colitis - - - EUR 247 059 - - - Sweden - - - Higher or Secondary Education Establishments - - The gastrointestinal tract is colonized by a community of microbes, the microbiota, which has a significant impact on human health and nutrition. The mucus gel layer structure provides the barrier between the microbiota and - the intestine preventing the occurrence of the inflammation process. Indeed, an altered microbiota (towards mucus degrading bacteria) and defects in the mucus structure have been shown to be associated with inflammatory bowel diseases, such as - ulcerative colitis. - - 2020-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Sweden - - - MUC - - - H2020-MSCA-IF-2016 - - - 748336 - - - - - UNIVERSITAT ZURICH - ASTON UNIVERSITY - UNIVERSITAET BAYREUTH - - - EUR 3 588 125 - - - Predictive Reagent Antibody Replacement Technology - - - EUR 3 588 125 - - - Switzerland - United Kingdom - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Predictive Reagent Antibody Replacement Technology (PRe-ART) will create a foundational new technology platform to completely replace conventional antibody technology within medical diagnostics and basic life science research. - In a multidisciplinary approach combining basic science, protein engineering and computational prediction, Pre-ART will generate non-antibody components which can be combined in an entirely modular fashion to create molecules that bind any peptide of - choice. Such a biotechnological revolution is timely because of current failings in the reagent antibody market, after forty years still based on monoclonal antibodies (mAbs) to detect biomolecules, when 50% of all commercial reagent mAbs have been - shown to not function correctly. - - - 2021-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-01-2016-2017 - FET-Open research and innovation actions - - - RIA - Research and Innovation action - - - Switzerland - - - PRe-ART - - - H2020-FETOPEN-1-2016-2017 - - - 764434 - - - - - ANTERYON BV - VRIJE UNIVERSITEIT BRUSSEL - - - EUR 1 011 868,56 - - - Next generation Compact Lightsource And Spectrometer Systems - - - EUR 1 011 868,56 - - - Netherlands - Belgium - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - Increasing health and environmental awareness of European citizens has led to an urgent demand for spectral analysis of matter. However, what is missing are novel and cost-effective methods to sense the desired analytes with - high sensitivity and high reliability using small and portable devices. Moreover, there is a severe shortage in the European spectroscopy industry of graduates and PhDs with the right expertise along the complete technology supply chain for the - development of such micro-spectrometer systems. Training and education in all its aspects, namely in optical modeling and design, fabrication and prototyping, measurements and characterization, sensor readout and data analysis towards proof-of - concept demonstration up to industrial valorisation of the micro-spectrometer systems is crucial, but to our knowledge not offered today as a whole. - - 2021-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-EID - European Industrial Doctorates - - - Netherlands - - - xCLASS - - - H2020-MSCA-ITN-2017 - - - 765635 - - - - - TECHNISCHE UNIVERSITAET GRAZ - ENTRECHEM SL - SAROMICS BIOSTRUCTURES AB - ERNST-MORITZ-ARNDT-UNIVERSITÄT GREIFSWALD - ENZYMICALS AG - KUNGLIGA TEKNISKA HOEGSKOLAN - DSM CHEMICAL TECHNOLOGY R & D BV - VIAZYM BV - UNIVERSIDAD DE OVIEDO - RUHR-UNIVERSITAET BOCHUM - UNIVERSITAET BIELEFELD - TECHNISCHE UNIVERSITAET BRAUNSCHWEIG - INNOSYN BV - - - EUR 2 787 956,64 - - - BIOCASCADES- Sustainable and Scalable Biocatalytic Cascade Reactions Training Network - - - EUR 2 787 956,64 - - - Austria - Spain - Sweden - Germany - Germany - Sweden - Netherlands - Netherlands - Spain - Germany - Germany - Germany - Netherlands - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - In BIOCASCADES, nine early-stage researchers (ESRs) will investigate the development of sustainable (chemo)enzymatic cascade reactions under the ‘green chemistry’ philosophy. The proposed BIOCASCADES project combines different - techniques such as compartmentalization, protein engineering and reaction engineering in order to develop commercially viable and environmentally benign one pot reactions. By avoiding intermediate downstream- and purification-steps, cascade reactions - minimize production costs, energy demand and waste production and are thus expected to make a major contribution for the development of sustainable and efficient production processes. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-EID - Marie Skłodowska-Curie Innovative Training Networks (ITN-EID) - - - MSCA-ITN-EID - European Industrial Doctorates - - - Austria - - - BIOCASCADES - - - H2020-MSCA-ITN-2014 - - - 634200 - - - - - UNIVERSITY OF ST MARK & ST JOHN - ASSOCIATION GENETHON - PANEPISTIMIO THESSALIAS - FONDAZIONE PER LA RICERCA BIOMEDICA AVANZATA ONLUS - STICHTING VU - THE UNIVERSITY OF LIVERPOOL - CHRISTOS PAPADOPOULOS & SIA O.E. - TZARTOS - DIAGNOSIS & RESEARCH IN NEUROIMMUNOLOGY MEDICAL LIMITED LIABILITY COMPANY - MYOMEDIX GMBH - DLD GESELLSCHAFT FUR DIAGNOSTIKA UND MEDIZINISCHE GERATE MBH - EUROPEAN MOLECULAR BIOLOGY LABORATORY - IMMUNDIAGNOSTIK AG - UNIVERSITAT KONSTANZ - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - ZENTRALINSTITUT FUER SEELISCHE GESUNDHEIT - University of Florida - STELLENBOSCH UNIVERSITY - - - EUR 1 458 000 - - - Muscle Stress Relief: An integrated research program linking together basic research on secondary myopathies in stress states to innovative translation in applied myology. - - - EUR 1 606 500 - - - United Kingdom - France - Greece - Italy - Netherlands - United Kingdom - Greece - Greece - Germany - Germany - Germany - Germany - Germany - Germany - Germany - United States - South Africa - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - A diverse variety of medical or lifestyle conditions lead to a progressive loss of muscle force by functionally impairing myofibril contractility and causing ultimately myofibril loss. Major underlying risk factors of chronic - muscle force loss are ageing, inactive lifestyles, and unbalanced nutrition. Together, these factors are predicted to lead to an endemic incidence of muscle weakness both in the developed countries. Clinical research on the mechanisms involved - requires a multidisciplinary approach covering aspects of ageing, metabolism, and on the humoral cross-talk of muscle with other key organs including heart, liver, kidney, and lung. To achieve this, six European groups with complementary expertise in - inter-organ-cross-talk during stress-induced secondary myopathies will team-up with a leading team in the U.S. with expertise in the translation of muscle research into therapeutic interventions, and with one team from South Africa with cutting-edge - expertise in the regulation of regenerative capacities in muscle. - - - 2020-02-29, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - United Kingdom - - - Muscle stress relief - - - H2020-MSCA-RISE-2014 - - - 645648 - - - - - UNIVERSITAET BERN - UNIVERSITAET BERN - - - EUR 2 500 000 - - - DEVELOPMENT OF HEALTHY HOST-MICROBIAL MUTUALISM IN EARLY LIFE - - - EUR 2 500 000 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Background - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Switzerland - - - HHMM-Neonates - - - ERC-2016-ADG - - - 742195 - - - - - TEL AVIV UNIVERSITY - TEL AVIV UNIVERSITY - - - EUR 1 345 282 - - - C° symplectic geometry - - - EUR 1 345 282 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - "The objective of this proposal is to study ""continuous"" (or C^0) objects, as well as C^0 properties of smooth objects, in the field of symplectic geometry and topology. C^0 symplectic geometry has seen spectacular progress - in recent years, drawing attention of mathematicians from various background. The proposed study aims to discover new fascinating C^0 phenomena in symplectic geometry. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Israel - - - CSG - - - ERC-2017-STG - - - 757585 - - - - - ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM - ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM - - - EUR 149 938 - - - Real-time tracking of whisker kinematics for closed-loop neuroscientific experiments - - - EUR 149 938 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - We study the sensorimotor adaptation in the cerebellum with the whiskers of the mouse as a model system. The whiskers are a sophisticated sensorimotor apparatus with which the mouse actively profiles its immediate 3D - environment by swiftly whisking. To estimate distances, orientation and texture of its surroundings, the mouse uses a ‘maximum contact, minimum penetration’ scheme, with sensorimotor decisions taking place within as little as 10 ms. This scheme - imposes the main experimental challenge to whisker-based studies: hair-like structures moving at high speeds need to be tracked accurately to ascribe whisker motion to cerebellar function. In order to capture the motion of the whiskers accurately, - high-speed image acquisition at high frame rates (ca. 1000 fps) is required. On account of the paradigms developed to relate neural activity to whisker behavior, high-throughput and real-time whisker tracking are required. We have evaluated all - presently available whisker-tracking tools that delivered the desired kinematics of whisker behavior. However, all have failed in terms of computational time and/or acquisition frequency, which rendered them unsuited both for offline use and for - real-time applications. To address these limitations, we propose the commercialization of WhiskTrackGP, a high-performance image-acquisition and -processing platform for bleeding-edge neuroscientific experiments on behavior. WhiskTrackGP is a - hardware-software platform that can recognize the kinematics of multiple whiskers simultaneously with minimal intervention from the experimenter. It is realized as powerful whisker-tracking software ported on a special hardware platform based on - NVidia GP-GPUs and Maxeler Dataflow-Engines. We demonstrate accelerated offline video analysis in the order of 10000x (from an original processing time of 9.4 sec down to 0.9 msec). WhiskTrackGP comprises a “one-stop shop” solution for labs and - companies active in the field of behavioral studies. - - 2018-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Netherlands - - - WhiskTrackGP - - - ERC-2017-PoC - - - 768914 - - - - - GLOBAL LIGHTNING PROTECTION SERVICES AS - UNIVERSITY OF SOUTHAMPTON - - - EUR 1 093 151,52 - - - Lightning protection of wind turbine blades with carbon fibre composite materials - - - EUR 1 093 151,52 - - - Denmark - United Kingdom - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - The consortium behind SPARCARB – Global Lightning Protection Services A/S (GLPS, non-academic beneficiary), Denmark, together with the University of Southampon (SOTON, academic beneficiary entitled to award doctoral degrees), - UK, and six Partner organizations – aims at providing an innovative international, interdisciplinary and intersectoral training network for four Early-Stage Researcher (ESRs), which will integrate in a single project (1) Science-based Training in - material and electrical engineering; (2) Transferable Skills-based Training in carbon fibre, wind turbines, lightning protection technologies, business and innovation, and other competences; (3) and Research-based Training designed around - cutting-edge challenges for the Wind Power Industry, which has identified the need for continuous research on lightning protection of large wind turbines with blades incorporating CFC structural components. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-EID - Marie Skłodowska-Curie Innovative Training Networks (ITN-EID) - - - MSCA-ITN-EID - European Industrial Doctorates - - - Denmark - - - SPARCARB - - - H2020-MSCA-ITN-2014 - - - 642771 - - - - - TEL AVIV UNIVERSITY - TEL AVIV UNIVERSITY - - - EUR 1 499 375 - - - from SPArsity to DEep learning - - - EUR 1 499 375 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Lately, deep learning (DL) has become one of the most powerful machine learning tools with ground-breaking results in computer vision, signal & image processing, language processing, and many other domains. However, one of - its main deficiencies is the lack of theoretical foundation. While some theory has been developed, it is widely agreed that DL is not well-understood yet. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Israel - - - SPADE - - - ERC-2017-STG - - - 757497 - - - - - COMMUNAUTE D' UNIVERSITES ET ETABLISSEMENTS UNIVERSITE BOURGOGNE - FRANCHE - COMTE - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - FOUNDATION FOR THEORETICAL AND COMPUTATIONAL PHYSICS AND ASTROPHYSICS - TECHNISCHE UNIVERSITAT DARMSTADT - THE UNIVERSITY OF SUSSEX - UNIVERSITE DE TECHNOLOGIE DE TROYES - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - QUTOOLS GMBH - QUBIG GMBH - TEEM PHOTONICS SA - - - EUR 3 833 637,12 - - - Light-Matter Interfaces for Quantum Enhanced Technology - - - EUR 3 833 637,12 - - - France - United Kingdom - Bulgaria - Germany - United Kingdom - France - Switzerland - Germany - Germany - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Quantum technology means the ability to organise and control the components of a functional system governed by the laws of quantum physics. The goal of this project is to train high-level young researchers through the - development of innovative techniques to interface light and matter at the quantum level using atoms, nanostructures and photons, with applications in optics and quantum information processing. Well-trained and versatile researchers are needed to - satisfy the demands of this rapidly growing field, in which there is also a strong drive and low threshold for industrial involvement. A prerequisite for success is the enhancement of the close connection between experimental, technological and - theoretical studies. The proposed network, Light-Matter Interfaces for Quantum Enhanced Technology, LIMQUET, consists of seven academic and three industrial beneficiaries, complemented by one industrial partner. The academic partners are experienced - but reasonably young groups with already established collaborations. The industrial partners have experience in developing and manufacturing high-quality components for research and industrial purposes. Within the Network, we anticipate highlights in - (i) light-matter interfaces at the quantum level through the realisation of quantum networks using atoms, ions, and photons, (ii) the interfacing of light with light, in particular for light storage, (iii) adapting strategies originally developed in - quantum optics to an integration into designed nanostructures, and (iv) the development of robust tools for quantum control and photonics. The training Network will enhance and use the synergy between the partners to produce a high-level doctoral - training program in the field of quantum research and technology, including complementary skills and a pertinent impact of outreach activities. In order to enhance their career perspectives, all the ESRs will be jointly supervised and will be hosted - on secondment by a company of the project. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - France - - - LIMQUET - - - H2020-MSCA-ITN-2017 - - - 765075 - - - - - UNIVERSITE D'AIX MARSEILLE - - - EUR 173 076 - - - Epigenetic control of retinoic acid-dependent genes during heart development - - - EUR 173 076 - - - France - - - Higher or Secondary Education Establishments - - EPIGENHEART proposes a unique and competitive training for heart development research centred on congenital heart diseases (CHD), a leading cause of death in Europe . Defects in the pathways involved in myocardial lineages at - the venous pole of the heart are found to be the origin of CHD and atrial arrhythmias. Epigenetic gene regulation has influence in maintenance of cellular identity, differentiation, and is deregulated in many diseases. The involvement of epigenetic - dysregulation in CHD is poorly described, much of the mechanistic detail involved in triggering these events in the context of heart development remains unclear. RA signalling is preferentially active in the venous pole region of the embryonic heart. - A deregulation of the retinoic acid (RA) has been implicated in venous pole defects in patients. How RA signalling takes part in the genetic and epigenetic network regulating the venous pole lineage decisions needs to be studied in details. With the - use of in vitro, ex vivo and in vivo approaches in transgenic and deficient mouse embryos combined with transcriptomic and chromatin profiling, the two interacting research lines of EPIGENHEART fulfils this goal. EPIGENHEART is expected to increase - the knowledge on the genetic and epigenetic network regulating the formation of the venous pole, which will contribute to better understand the associated heart diseases. Apart from the impact on human health, the project will contribute to ER´s - future career prospects and European scientific excellence and competitiveness. - - 2017-06-30, Grant Agreement terminated | - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - EPIGENHEART - - - H2020-MSCA-IF-2014 - - - 661183 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 2 208 618,75 - - - Visualising transport dynamics of transmembrane pumps - - - EUR 2 208 618,75 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The project will investigate multi-component molecular machines that drive substrates across the cell envelope of bacteria. Some of the machines pump antibiotics or toxins, and so contribute to drug resistance and virulence in - pathogenic strains. Questions that will be addressed include what the molecular pumps look like, how they are assembled and regulated, how they capture and translocate substrates, and the stereochemical basis for the cooperative switching of - substrate-binding states. Molecular pumps that will be studied include tripartite systems driven by ATP hydrolysis, which play a central role in the efflux of macrolide antibiotics and secretion of toxins in Gram-negative bacteria, and those that use - secondary transporters energized by electrochemical gradients. We will build upon our earlier observations to prepare a series of intermediates encompassing the key steps in the transport processes, to visualize tertiary and quaternary structural - changes, the pathway of substrates in the efflux pumps, and the threading of toxin polypeptides through the constricted channel in the secretion assembly. The pumps and secretion systems cycle through intermediate states, and these will be studied at - high resolution by cryoEM and crystallography to understand how the conformational states switch with strong cooperativity and avoid futile cycles that dissipate energy. Our work indicates that the activity of these transporters can be modulated by - small peptides and potential co-factors, and we will address how these work. The project will build on our novel approach to engineer the pump assemblies that enables structural analysis at high resolution in isolation and in situ, and will be - complemented with mechanistic analyses in vitro and in vivo. The project will deliver a comprehensive, structure-based description of the mechanism of drug efflux and protein translocation by transport machines and their regulation in diverse - pathogenic bacteria. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - VisTrans - - - ERC-2016-ADG - - - 742210 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - - - EUR 212 016,60 - - - Processes of indigenous community resistance to large extractive projects and their struggles for autonomy in Chile and Peru - - - EUR 212 016,60 - - - Ireland - - - Higher or Secondary Education Establishments - - The aim of this Fellowship is for the researcher, Dr Rajiv Maher, to develop his professional capacity, advanced training, interdisciplinary skills, high-impact dissemination, and practical experience in line with the criteria - for a leading independent researcher in the EU. This proposal aims to investigate the processes of indigenous community resistance to large natural resource extraction projects and their struggles for autonomy in Chile and Peru. The proposal will - also examine the strategies used by companies and governments to gain community acceptance such as those relating to Corporate Social Responsibility (CSR). - - 2019-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Ireland - - - LandGrab - - - H2020-MSCA-IF-2015 - - - 707485 - - - - - UNIVERSITAETSKLINIKUM HAMBURG-EPPENDORF - UNIVERSIDAD POMPEU FABRA - UNIVERSITAET OSNABRUECK - KUNGLIGA TEKNISKA HOEGSKOLAN - GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER - WHITEMATTER LABS GMBH - THE UNIVERSITY OF HERTFORDSHIRE HIGHER EDUCATION CORPORATION - PAL ROBOTICS SL - - - EUR 3 778 125 - - - Socialising Sensori-Motor Contingencies - - - EUR 3 778 125 - - - Germany - Spain - Germany - Sweden - Germany - Germany - United Kingdom - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - As robots become more omnipresent in our society, we are facing the challenge of making them more socially competent. However, in order to safely and meaningfully cooperate with humans, robots must be able to interact in ways - that humans find intuitive and understandable. Addressing this challenge, we propose a novel approach for understanding and modelling social behaviour and implementing social coupling in robots. Our approach presents a radical departure from the - classical view of social cognition as mind-reading, mentalising or maintaining internal rep-resentations of other agents. This project is based on the view that even complex modes of social interaction are grounded in basic sensorimotor interaction - patterns. SensoriMotor Contingencies (SMCs) are known to be highly relevant in cognition. Our key hypothesis is that learning and mastery of action-effect contingencies are also critical to enable effective coupling of agents in social contexts. We - use “socSMCs” as a shorthand for such socially rele-vant action-effect contingencies. We will investigate socSMCs in human-human and human-robot social interaction scenarios. The main objectives of the project are to elaborate and investigate the - concept of socSMCs in terms of information-theoretic and neurocomputational models, to deploy them in the control of humanoid robots (PR2, REEM-C) for social entrainment with humans, to elucidate the mechanisms for sustaining and exercising socSMCs - in the human brain, to study their breakdown in patients with autism spectrum disorders, and to benchmark the socSMCs approach in several demonstrator scenarios. Our long term vision is to realize a new socially competent robot technology grounded in - novel insights into mechanisms of functional and dysfunctional social behavior, and to test novel aspects and strategies for human-robot interaction and cooperation that can be applied in a multitude of assistive roles relying on highly compact - computational solutions. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.2."> - - - FETPROACT-2-2014 - Knowing, doing, being: cognition beyond problem solving - - - RIA - Research and Innovation action - - - Germany - - - socSMCs - - - H2020-FETPROACT-2014 - - - 641321 - - - - - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - - - EUR 195 454,80 - - - Developing a Fibrosis Targeting and Tissue Reparative (FiTTeR) Therapy for the Infarcted Myocardium via an Injectable Functionalized Extracellular Matrix Hydrogel - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - As a Marie Skłodowska-Curie Fellow, I will develop, characterize, and determine the efficacy of a biomaterial platform to target pathologic fibrosis and promote tissue repair following myocardial infarction (MI). I have an - ideal background and will perform well in this project based on my expertise in extracellular matrix (ECM) derived biomaterials, characterizing the immune response to biomaterials, and evaluating in vivo outcomes. The proposed system will consist of - a protein fragment tethered to an injectable hydrogel. The hydrogel carrier will be composed of ECM, which has been shown to facilitate tissue repair processes by local modulation of immune cell phenotype . The cryptic protein fragment, recently - isolated and recombinantly produced by the Stevens Group , has gained attention for its ability to regulate the onset of fibrosis by interfacing with cells to abrogate the release of matrix metalloproteinases (MMPs). No therapies currently exist to - prevent or mitigate fibrosis. Developing a sophisticated delivery system for a cryptic protein fragment will enable the broad potential of targeting pathologic fibrosis to be realized. This system will be advantageous in simultaneously providing - localized delivery, combined immunomodulatory and regulatory properties of the ECM and recombinant protein fragment, and sustained release of the protein fragment during degradation of the ECM hydrogel. The combination of my expertise (in ECM - hydrogels, characterizing the host response to biomaterials, and translating technologies) and Prof Molly Stevens’s supervision and world-class interdisciplinary biomaterials-focused group, the 2014 Research Group of the Year (European Life Science - Awards), at Imperial College London (ICL), together make this project ideally suited for success. - - 2019-08-20, ongoing project - - - 2017-08-21 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - FiTTeR - - - H2020-MSCA-IF-2016 - - - 746980 - - - - - TECHNISCHE UNIVERSITAET WIEN - - - EUR 178 156,80 - - - Nanofiber-based atomic Bragg structures - - - EUR 178 156,80 - - - Austria - - - Higher or Secondary Education Establishments - - In this proposal, we want to create an atomic Bragg structure by carefully adjusting the inter-atomic spacing between nanofiber-trapped atoms to approach a Bragg resonance. The structure allows to engineer the atom-nanofiber - coupling for quantum-information applications. We hence build on the recent rapid progress of a novel light-matter interface based on an atomic ensemble trapped in an optical lattice created by the evanescent field of nanofiber-guided light. The - small effective area of the evanescently guided light field results in a large optical depth per atom on the few-percent level. The number of atoms can easily reach several thousands for nanofibers with a length of few millimeres. In combination with - the proven coherence properties, it is an ideal candidate for the implementation of fundamental building blocks for quantum information processing (QIP), such as efficient fiber-integrated quantum memories for light and optical nonlinearities on the - few-photon level. However, in view of recent discoveries related to the coupling between polarization and propagation direction of the nanofiber modes, we believe that the true potential of the nanofiber system can only be unleashed by developing - specialized protocols. Those protocols need to take the extraordinary polarization properties of the nanofiber-guided modes and the multilevel structure of the atoms into account. Specialized protocols will benefit from the enhanced coupling of the - atoms to the nanofiber provided by the Bragg structure. We will characterize the transmission and reflection properties of the nanofiber-coupled atomic Bragg structure, with special attention to polarization effects. Subsequently we will demonstrate - how the Bragg resonance can be used to enhance the spontaneous emission of the atomic array into nanofiber-guides modes with a desired propagation direction and how this significantly improves the success rate of the DLCZ quantum memory protocol. - - 2017-08-31, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Austria - - - NanoBragg - - - H2020-MSCA-IF-2014 - - - 658556 - - - - - UNIVERSITEIT VAN AMSTERDAM - - - EUR 177 598,80 - - - Initial conditions of exoplanet formation in protoplanetary disks - - - EUR 177 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - There is now a substantial population of exoplanets with well-determined masses, radii, and orbital parameters in a range of host stellar systems. JWST will bring an increase in exoplanets with atmospheric spectroscopy - measurements, moving the field from pure discovery to population synthesis and characterization. Many of the best-studied planetary systems are massive and located within 1AU of their central stars; it is not clear whether all of these planets - migrated from farther out in their natal disks to this location or if they could have formed in situ. Both scenarios should produce distinct compositions resulting from multiple strong, time-dependent chemical gradients in their disks due to thermal - sublimation and grain processing effects. These effects likely set the bulk chemical composition of the planet’s core and atmosphere, which are accreted from different material in the disk. By determining the physical conditions within 1AU, I will - confirm whether they are sufficient to support in situ planet formation. I will also map the distribution of key planetary building blocks in both the solid phase (dust grains) and gas phase. This will be accomplished by interpreting disks’ flux as a - function of wavelength with radiative transfer models including detailed sublimation and condensation physics, and comparing observed spectral features in both the solid and gaseous phases in molecular and atomic form to those predicted by models. - This project will provide training through research in numerical methods and exoplanet characterization techniques, which are important in the long term for my career goals to lead a research group in planetary formation. Through development courses, - I will improve my marketability for senior research positions and in turn transfer my infrared observing skills and US and European network connections to the host. This project increases the visibility of the host and European exoplanetary astronomy - on an international scale. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - ICED - - - H2020-MSCA-IF-2016 - - - 749864 - - - - - UNIVERSITY COLLEGE LONDON - UNIVERSITY COLLEGE LONDON - - - EUR 2 163 061 - - - Advanced clinical photoacoustic imaging systems based on optical microresonator detection - - - EUR 2 163 061 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Photoacoustic imaging is widely viewed as one of the most exciting and promising biomedical imaging techniques to have emerged in recent years. It offers major opportunities for increasing our understanding of basic biological - processes at an anatomical, physiological and molecular level, and for improving the clinical diagnosis and treatment of cancer and other major diseases. The aim of this project is to develop and evaluate a new generation of advanced photoacoustic - scanners for clinical photoacoustic imaging based on a novel, highly sensitive, optical microresonator ultrasound sensor. This type of sensor offers the prospect of a major step forward in terms of imaging performance by providing orders of magnitude - higher sensitivity than equivalently sized conventional detectors with the necessary broadband frequency response and small element size for high image quality. As a consequence, it promises greater penetration depth and improved image quality than - possible with current state-of-the-art photoacoustic scanners. This will pave the way for in vivo high resolution human imaging at depths currently unattainable, opening up entirely new clinical applications in oncology, cardiovascular medicine, - regenerative medicine and other areas which have hitherto been impossible due to hardware limitations. The project will involve the development of novel polymer optical microresonator sensors, advanced parallelised optical read-out schemes for - real-time image acquisition, and engineering complete imaging instruments for use in clinical studies. These instruments will then be evaluated in a variety of clinical contexts including the assessment of skin cancer, head and neck cancers, - cardiovascular disease and reconstructive surgery. - - 2022-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - Photoclin - - - ERC-2016-ADG - - - 741149 - - - - - THE UNIVERSITY OF WARWICK - THE UNIVERSITY OF WARWICK - ECOLE DES HAUTES ETUDES EN SCIENCES SOCIALES - - - EUR 150 000 - - - The International Register of Academic Job Categories. Facilitating Careers in the European Research Area - - - EUR 150 000 - - - United Kingdom - United Kingdom - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The Proof of Concept INTAC project will create a prototype of an online Register which systematically lists, explains and compares formal job categories and status positions of research- and teaching staff in 575 higher - education institutions in France, Germany and Great Britain. It will set up the Register on a public multilingual platform and provide resources for career-relevant decision-making (such as career guidelines, CV templates, visualisation and mapping - tools for career tracks and status systems, identifier of job equivalents, a community forum). While international academic mobility is growing at high rates and academic systems are rapidly changing, job-seekers as well as recruiting institutions - often grapple with the fact that job and status categories in academic institutions (such as PRAG, Akademische Rätin or Teaching Fellow) are difficult to understand for those coming from other institutions or systems. As a consequence, academics may - not recognize the most suitable career paths and academic institutions may not receive the best applications. Responding to a demand from academics, employers, unions, associations and organisations in the higher education sector, the INTAC Register - aims to facilitate academic recruitments, make national and international academic job markets more transparent and help academic career planning in the European Research Area. In order to bring the Register to the market, INTAC will create a - diversified revenue stream, including regular premium user fees and licensing to academic social media. Future sponsors from the public sector will be invited to commission more institutions, countries and service functions to be included into the - Register. INTAC draws on the comparative research of the ERC DISCONEX (“The Discursive Construction of Academic Excellence”) project on categorizations and careers of academic researchers in the UK, France, Germany and the U.S. - - 2019-04-30, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - INTAC - - - ERC-2016-PoC - - - 754895 - - - - - CENTRE INTERNATIONAL DE RECHERCHE AUX FRONTIERES DE LA CHIMIE - CENTRE INTERNATIONAL DE RECHERCHE AUX FRONTIERES DE LA CHIMIE - - - EUR 150 000 - - - ITO-free multi-coloured nanoscale engineered OLEDs for large-area flexible lighting and full-colour active-matrix displays - - - EUR 150 000 - - - France - France - - - Research Organisations - Research Organisations - - FlexNanoOLED aims at expanding the groundbreaking research developed within the ERC project SUPRAFUNCTION into a radically new and unprecedented technology to enable the fabrication of flexible ITO-free multi-coloured - nanoscale engineered organic LEDs. In a recent breakthrough, we have developed a novel device architecture for optoelectronics which relies on a nanomesh scaffold and demonstrated its full potential by realising supramolecular nanowire photovoltaic - devices with performances surpassing those of standard organic photodetectors. - - 2019-03-31, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - France - - - FlexNanoOLED - - - ERC-2017-PoC - - - 766936 - - - - - EBERHARD KARLS UNIVERSITAET TUEBINGEN - EBERHARD KARLS UNIVERSITAET TUEBINGEN - - - EUR 2 496 875 - - - Wide Incremental learning with Discrimination nEtworks - - - EUR 2 496 875 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Although homo sapiens has been endowed with language for over 50,000 years, the invention of alphabet-like scripts 3,000 years ago dominates Western linguistic thinking. Training in literacy starts in early childhood, and - because of this, words and letter-like sound units can naturally seem to be the building blocks of language. The Chinese writing system highlights the cultural-specificity of this approach: characters are juxtaposed without intervening spaces, and - their interpretation is highly context-dependent. Words are not singled out. And although more frequent characters contain parts indicating pronunciation, it is syllables that are referred to, not letter-like sound units. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - WIDE - - - ERC-2016-ADG - - - 742545 - - - - - FREIE UNIVERSITAET BERLIN - FREIE UNIVERSITAET BERLIN - - - EUR 148 500 - - - EVOLchip - predicting antibiotic resistance for sustainable antibiotic stewardship - - - EUR 148 500 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Antibiotic resistance is rife (fig. 1), yet notoriously difficult to predict. Here I propose to assess the applied potential of an easy to use device, ‘EVOLchip’ that allows to test antibiotic treatment schemes within a few - weeks for their risk of inducing antimicrobial resistance. If successful, this would allow to use current antibiotics much longer and to reuse old antibiotics in combination. Such tests can be conducted at hospital level by any trained medical - microbiologist and hence be implemented into routine antibiotic stewardship. - - - 2019-04-30, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Germany - - - Evolchip - - - ERC-2017-PoC - - - 768210 - - - - - UNIVERSITY COLLEGE LONDON - UNIVERSITY COLLEGE LONDON - - - EUR 2 499 954 - - - Control of cerebral blood flow by capillary pericytes in health and disease - - - EUR 2 499 954 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Pericytes, located at intervals along capillaries, have recently been revealed as major controllers of brain blood flow. Normally, they dilate capillaries in response to neuronal activity, increasing local blood flow and - energy supply. But in pathology they have a more sinister role. After artery block causes a stroke, the brain suffers from the so-called “no-reflow” phenomenon - a failure to fully reperfuse capillaries, even after the upstream occluded artery has - been reperfused successfully. The resulting long-lasting decrease of energy supply damages neurons. I have shown that a major cause of no-reflow lies in pericytes: during ischaemia they constrict and then die in rigor. This reduces capillary diameter - and blood flow, and probably degrades blood-brain barrier function. However, despite their crucial role in regulating blood flow physiologically and in pathology, little is known about the mechanisms by which pericytes function. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - BrainEnergy - - - ERC-2016-ADG - - - 740427 - - - - - AALTO-KORKEAKOULUSAATIO - AALTO-KORKEAKOULUSAATIO - - - EUR 150 000 - - - Transparent and Flexible Li-Organic 3D Thin-Film Microbattery - - - EUR 150 000 - - - Finland - Finland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In this Proof-of-Concept project we will demonstrate the practical feasibility of a fundamentally novel transparent and flexible Li-organic thin-film microbattery. The strong basis for the project is the new hybrid Li-organic - electrode materials discovered in the PI's ERC Advanced Grant Project “Molecular-Layer-Engineered Inorganic-Organic Hybrid Materials (LAYERENG-HYBMAT)”. These hybrid thin-film materials are fabricated by the combined atomic/molecular layer deposition - (ALD/MLD) technique which uniquely allows for fabrication of highly conformal thin-film coatings on various flexible, sensitive, functional and/or nanostructured surfaces. Within this PoC project we will (1) design and construct an actual optimized - all-ALD/MLD Li-organic battery cell, (2) confirm its optical transparency and mechanical flexibility as expected, (3) identify the most potential applications for this new type of 3D thin-film microbattery, (4) assess its real-life business - opportunities, and (5) build up a network of academic and industrial collaborators for the further advancement of the novel technology. - - 2018-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Finland - - - TransFlexBattery - - - ERC-2017-PoC - - - 780041 - - - - - UNIVERSIDAD POMPEU FABRA - UNIVERSIDAD POMPEU FABRA - - - EUR 150 000 - - - Technologies for Supporting Online Music Education - - - EUR 150 000 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Online learning has impacted and changed music education significantly all over the world in the last decade. Music schools and teachers have now access to a much wider audience, increasing their business opportunities - specially by overcoming the geographical constraints. However, online music performance education cannot scale to MOOC level given that the student assessments rely on individual instructor review, as is the case in the well known online courses from - Berklee Online. The need of a personal assessment procedure limits the growth and expansion of these courses. - - 2019-03-31, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Spain - - - TECSOME - - - ERC-2017-PoC - - - 768530 - - - - - KATHOLIEKE UNIVERSITEIT LEUVEN - - - EUR 160 800 - - - Solving large systems of polynomial equations by using multi-linear algebra tools - - - EUR 160 800 - - - Belgium - - - Higher or Secondary Education Establishments - - The modelling of real-life nonlinear processes is commonly done via local linearization, i.e., by fitting linear models to small ranges of the process. Linearization is, however, quite limited in range and model properties. A - foundational step is currently being made by moving from linear to multi-linear or polynomial models to capture more general features of a nonlinear process over larger ranges. A second important development is Big Data: nowadays we often encounter - high-dimensional datasets with multiple `independent’ modes of variation. This increases the numbers of equations and variables and the degrees of the polynomials in the multi-linear models that are required. Big Data research is a key priority in - the EU Horizon 2020 Work Programme. - - 2019-08-31, Grant Agreement terminated - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Belgium - - - TENSOROOTS - - - H2020-MSCA-IF-2016 - - - 746979 - - - - - UNIVERSITAET BERN - UNIVERSITAET BERN - - - EUR 140 625 - - - Development of a compact, user-friendly and cost effective source for the generation of powerful and broad ultrashort pulses in the deep-UV - - - EUR 140 625 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Here we present an original design of a compact and portable set-up able to generate very broadband (70-100 nm at 300 nm) and powerful (>1uJ/pulse) ultrashort deep-UV pulses. Compared with other schemes, it guarantees an - aberration-free propagation, an easy installation and minimal dispersion. The present project aims to bring the current prototype to the level of a commercial device. The conceived design will allow to manufacture a compact, portable and cost - effective device, which will be user-friendly and with almost no required maintenance. - - - 2019-06-30, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Switzerland - - - DUVlight - - - ERC-2017-PoC - - - 768598 - - - - - UNIVERSITAT ZURICH - UNIVERSITAT ZURICH - - - EUR 1 008 665 - - - Inequality - Public Policy and Political Economy - - - EUR 1 008 665 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Over the past decades, many developed countries have seen considerable increases in income and wealth inequality. Political and economic arguments for and against offsetting this rise in inequality have been put forward. This - research program aims at informing this debate by developing new models that capture these trends and by analyzing their optimal policy implications, both theoretically and quantitatively. The goal is to bring together approaches from public - economics, labor economics, macroeconomics, and political economy to explore whether rising inequality necessitates institutional responses and, if so, which ones. - - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Switzerland - - - IneqPol - - - ERC-2017-STG - - - 757721 - - - - - UNIVERSITAT ZURICH - UNIVERSITAT ZURICH - - - EUR 150 000 - - - Neuroprotective human antibodies to the flexible tail of the prion protein - - - EUR 150 000 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The misfolding of the cellular prion protein (PrPC) causes infectious neurodegenerative conditions called prion diseases. In the framework of the ERC-funded study “The Prion Protein in Health and Disease” the team of Adriano - Aguzzi has discovered that antibodies against the flexible tail (FT) of PrPC are neuroprotective against prion pathologies. Here we propose to clone and express such antibodies from humans and to develop them as antiprion therapeutics. The principal - investigator has founded a company (www.mabylon.com) which has established a high-yield method for cloning paired heavy and light chains from human memory B cells. The proposed research program will identify rare anti-FT immunoreactive individuals - among large populations by high-throughput screening. The clinical information of the selected individuals will help to identify antibodies from persons devoid of pathologies that may be related to anti-PrPC autoimmunity. Therefore, the human - antibodies generated within this program will represent fast-track investigational new drug (IND) candidates with safety profiles superior to those of murine or humanized antibodies. Completion of the proposed activities will lead to the development - of therapies against prion diseases, which are currently considered untreatable and invariably fatal. - - 2019-02-28, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Switzerland - - - NeuroQure - - - ERC-2017-PoC - - - 768415 - - - - - INSTITUTO POLITECNICO DO PORTO - UNIVERSITAET DUISBURG-ESSEN - UNIVERSIDAD DE SALAMANCA - VIRTUAL POWER SOLUTIONS SA - NEBUSENS, S.L. - DISCOVERGY GMBH - - - EUR 2 160 000 - - - Enabling Demand Response for short and real-time Efficient And Market Based smart Grid Operation - An intelligent and real-time simulation approach - - - EUR 2 385 000 - - - Portugal - Germany - Spain - Portugal - Spain - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Smart Grid (SG) concepts are rapidly being transferred to the market and huge investments have been made in renewable based electricity generation and rolling out smart meters. However, the present state of the art does not - ensure neither a good return of investment nor a sustainable and efficient power system. The work so far in the EU involves mainly larger stakeholders, namely power utilities and manufacturers more focused on production and grid resources. A closer - attention to the demand side of the system is required, and especially in the interaction with the new methods for SG management. - - 2019-01-31, ongoing project - - - 2015-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Portugal - - - DREAM-GO - - - H2020-MSCA-RISE-2014 - - - 641794 - - - - - LUNDS UNIVERSITET - - - EUR 1 674 240 - - - The Translational Cancer Faster Forward doctoral programme – CanFaster - - - EUR 3 348 480 - - - Sweden - - - Higher or Secondary Education Establishments - - CanFaster is a joint venture among industry, health care and academia to enhance and accelerate innovations and clinical implementation within oncology. The vision of CanFaster is to prolong and save lives of cancer patients - through integrated development and commercialization/implementation of diagnostic/treatment alternatives, thus reaching the market and patient more rapidly. CanFaster will save lives of cancer patients, not for future generations, but for today´s. - The CanFaster programme is enabled by an intimate collaboration between industry, health care system and academia (in total ~7 million Euro will be invested), and will contribute to the Europe 2020 strategy, where one million new research jobs are - needed to reach the Innovation Union flagship initiative. The collected track record of all partners in the proposed CanFaster programme demonstrates an impressive history of entrepreneurial spirit, state-of the art medical care but also truly - world-class scientific excellence within translational cancer research. The CanFaster regional doctoral programme, recruiting 16 ESRs, will be hosted within CREATE Health, a translational cancer research programme with broad international - collaboration partners and excellent out-put for the last 10 years. Main objectives of CanFaster are (i) Increased transnational and intersectorial mobility (ii) Intersectorial improvements through intensified collaboration within oncology between - academia, industry and hospital/regional health care organisations. (iii) Acceleration of innovation, attracting international investors leading to increased number of SMEs in the region and (iv) Education of a new generation of excellent - multidisciplinary, entrepreneurial scientists. This is achieved through the attraction of the MSCA program for industrial partners to add-on to the EU and public national funding of the programme with financial and in-kind contribution. - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2016 - Co-funding of regional, national and international programmes - - - MSCA-COFUND-DP - Doctoral programmes - - - Sweden - - - CanFaster - - - H2020-MSCA-COFUND-2016 - - - 754299 - - - - - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - ROBERT KOCH-INSTITUT - INSTITUTO NACIONAL DE SAUDE DR. RICARDO JORGE - Department of Health - FRIEDRICH LOEFFLER INSTITUT - BUNDESFORSCHUNGSINSTITUT FUER TIERGESUNDHEIT - Folkhälsomyndigheten (The Public Health Agency of Sweden) - HELLENIC PASTEUR INSTITUTE - INSERM - TRANSFERT SA - PRINS LEOPOLD INSTITUUT VOOR TROPISCHE GENEESKUNDE - SPITALUL CLINIC DR VICTOR BABES BUCURESTI - SVB - ISTITUTO NAZIONALE PER LE MALATTIE INFETTIVE LAZZARO SPALLANZANI-ISTITUTO DI RICOVERO E CURA A CARATTERE SCIENTIFICO - INSTITUTO DE SALUD CARLOS III - ORSZAGOS EPIDEMIOLOGIAI KOZPONT - MEDIZINISCHE UNIVERSITAT GRAZ - BERNHARD-NOCHT-INSTITUT FUER TROPENMEDIZIN - PHILIPPS UNIVERSITAET MARBURG - - - EUR 1 443 927 - - - European Research Infrastructure on Highly Pathogenic Agents 2 - - - EUR 1 443 927 - - - France - Germany - Portugal - United Kingdom - Germany - Sweden - Greece - France - Belgium - Romania - Italy - Spain - Hungary - Austria - Germany - Germany - - - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - - ERINHA2 aims to complete the work carried out during the first preparatory phase (PP1) - ERINHA - in order to reach the financial, administrative and technical maturity necessary to complete the establishment of the Research - Infrastructre and ensure that the operation phase can begin in 2018. ERINHA2 will therefore finalise the decision to use the status of an association and prepare the necessary legal document to register the RI depending on the country voted on to - host the Central Coordinating Unit. ERINHA2 will prepare all procedures and protocols (human resources, IPR, ethics) needed to effectively operate the RI. The financial and business plans prepared in ERINHA (PP1) will updated and presented to - national and international stakeholders to obtain their agreement to fund the infrastructure. An overarching group of activities - WP5, Stakeholders and commitment - will aim to accompany all partner countries in their efforts to obtain agreements - and funding. This WP5 will ensure all relevant stakeholders and potential users are informed of the progress, services and benefits of ERINHA. The utlimate outcome of ERINHA2 will be the signtature of the ERINHA statutes among the founding countries - to officially establish the RI and enter into the construction phase. - - 2017-06-30, closed project | - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-2-2015 - Preparatory Phase of ESFRI projects - - - CSA - Coordination and support action - - - France - - - ERINHA2 - - - H2020-INFRADEV-1-2015-2 - - - 689622 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - ETHNIKO IDRYMA EREVNON - UNIVERSITY OF SURREY - UNIVERSIDAD DE ZARAGOZA - RENISHAW PLC - M-SOLV LTD - THE UNIVERSITY OF SUSSEX - - - EUR 3 358 044 - - - Graphene-based nanomaterials for touchscreen technologies: Comprehension, Commerce and Communication - - - EUR 3 358 044 - - - France - Spain - Greece - United Kingdom - Spain - United Kingdom - United Kingdom - United Kingdom - - - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - “Enabling Excellence” offers integral R&D training at PhD level around one of the most active and exciting topics at the forefront of nanoscience and nanotechnology, graphene-based nanostructures and materials. We propose - a training experience built on three interrelated pillars, namely COMPREHENSION AND CONTROL, COMMERCE, and COMMUNICATION. - - 2019-03-31, ongoing project | - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - France - - - Enabling Excellence - - - H2020-MSCA-ITN-2014 - - - 642742 - - - - - KOBENHAVNS UNIVERSITET - SIMULA RESEARCH LABORATORY AS - UNIVERSITY OF GLASGOW - UNIVERSITEIT MAASTRICHT - UNIVERSITAETSKLINIKUM HAMBURG-EPPENDORF - ACESION PHARMA APS - CLYDE BIOSCIENCES LIMITED - - - EUR 4 101 221,52 - - - EU Training Network on Novel Targets and Methods in Atrial Fibrillation - - - EUR 4 101 221,52 - - - Denmark - Norway - United Kingdom - Netherlands - Germany - Denmark - United Kingdom - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The AFib-TrainNet consortium will enable promising young scientists to become excellent research leaders of the future, capable of fighting the challenges that Atrial Fibrillation (AF) presents to the European population. AF - is the most common sustained cardiac arrhythmia, occurring in between 1-2% of the general population. More than 6 million Europeans suffer from this arrhythmia and its prevalence is expected to increase by more than two-fold during the next 40 years - due to increased life expectancy. Thus, AF is said to assume epidemic proportions. Current options for pharmacological therapy are limited by both low efficacy and side effects, including life‐threatening ventricular arrhythmias and severe - extra-cardiac toxicities. - - 2019-08-31, ongoing project | - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Denmark - - - AFib-TrainNet - - - H2020-MSCA-ITN-2015 - - - 675351 - - - - - KOBENHAVNS UNIVERSITET - - - EUR 212 194,80 - - - Understanding the role of the rainbow trout metagenome on growth and health in aquaculturally farmed fish - - - EUR 212 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - Aquaculture is the fastest growing food-producing sector world-wide: >50% of consumed fish are farmed and the increasing human demand for high quality protein will continue. The most important challenge for securing - continued development of green aquaculture is sustainable solutions to improve feed efficiency as feed makes up >50% of the total cost for producing a fish. Further, animal protein is increasingly substituting plant based ingredients for fish - feed; this has yet unknown effects on related metabolic processes affecting growth and health. Promising solutions for optimizing feed efficiency and fish health stem from recent studies that sequence metagenomes (combined microbial DNA in the host - gut) to detail out how the complete gut microbiome (the microbial community in the gut) interacts with metabolic and immunological pathways in human and mice; results that have revolutionized the way we understand how microbes affects human health. - Identification of beneficial bacteria holds a huge potential for optimizing feed efficiency and boost immunity in farmed fishes. The aim of this project is to pursue this potential. I will apply a multidisciplinary approach using metagenomics to - describe, for the first time, the complete metagenome of the rainbow trout gut. This combined genomic resource will be coupled with carefully planned feeding experiments to identify associations with the host trout gut-microbiota and i) animal vs. - plant based diets, ii) genes of the host fish, and iii) individual growth and metabolic traits such as growth rate and fat content of the host trout. Results will yield new knowledge on microbe-host interactions in rainbow trout and may lead to new - products (e.g. probiotics and fish feed) enhancing fish health by actively modulating the microbiota. The project will additionally establish trout as a general model for the study of how modulation of the microbiota can give rise to increased health - and meat quality in any farmed animal. - - 2020-07-31, Grant Agreement signed - - - 2018-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Denmark - - - HappyFish - - - H2020-MSCA-IF-2016 - - - 745723 - - - - - EUROPEAN MOLECULAR BIOLOGY LABORATORY - ABO AKADEMI - CONSIGLIO NAZIONALE DELLE RICERCHE - UNIVERSITY OF DUNDEE - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - INSTITUTO DE SALUD CARLOS III - FUNDACIO CENTRE DE REGULACIO GENOMICA - FUNDACION PARA EL FOMENTO DE LA INVESTIGACION SANITARIA Y BIOMEDICA DE LA COMUNITAT VALENCIANA - INSTITUTO DE BIOLOGIA MOLECULAR E CELULAR-IBMC - MEDZINARODNE LASEROVE CENTRUM - USTAV MOLEKULARNI GENETIKY AKADEMIE VED CESKE REPUBLIKY VEREJNA VYZKUMNA INSTITUCE - UNIVERSITETET I OSLO - BIOTECHNOLOGY AND BIOLOGICAL SCIENCES RESEARCH COUNCIL - ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM - UNIVERSITE DE MONS - Masarykova univerzita - UNIVERSITEIT VAN AMSTERDAM - INSTYTUT BIOLOGII DOSWIADCZALNEJ IM. M. NENCKIEGO POLSKIEJ AKADEMII NAUK - WEIZMANN INSTITUTE OF SCIENCE - UNIVERSIDADE DE COIMBRA - ROUMEN TSANEV INSTITUTE OF MOLECULAR BIOLOGY BULGARIAN ACADEMY OF SCIENCES - - - EUR 1 497 910 - - - Euro-BioImaging Preparatory Phase II - Project - - - EUR 1 497 910 - - - Germany - Finland - Italy - United Kingdom - France - Spain - Spain - Spain - Portugal - Slovakia - Czech Republic - Norway - United Kingdom - Netherlands - Belgium - Czech Republic - Netherlands - Poland - Israel - Portugal - Bulgaria - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - Euro-BioImaging (EuBI) is the pan-European research infrastructure project for imaging technologies in biological and medical sciences and has been on the ESFRI Roadmap since 2008. In close match with the scope and objectives - of the INFRADEV2 call, Preparatory Phase II (PPII) funding will enable EuBI: - - 2018-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-2-2015 - Preparatory Phase of ESFRI projects - - - CSA - Coordination and support action - - - Germany - - - EuBI PPII - - - H2020-INFRADEV-1-2015-2 - - - 688945 - - - - - BIOBANKS AND BIOMOLECULAR RESOURCES RESEARCH INFRASTRUCTURE CONSORTIUM (BBMRI-ERIC) - STICHTING KANKERREGISTER - FONDATION REGISTRE DU CANCER - SCHWEIZERISCHER NATIONALFONDS ZUR FORDERUNG DER WISSENSCHAFTLICHEN FORSCHUNG - MASARYKUV ONKOLOGICKY USTAV - CHARITE - UNIVERSITAETSMEDIZIN BERLIN - TARTU ULIKOOL - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - IDRYMA IATROVIOLOGIKON EREUNON AKADEMIAS ATHINON - ACADEMISCH ZIEKENHUIS LEIDEN - NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU - WROCLAWSKIE CENTRUM BADAN EIT+ SPZOO - KAROLINSKA INSTITUTET - DOKUZ EYLUL UNIVERSITESI - CENTRE INTERNATIONAL DE RECHERCHE SUR LE CANCER - KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN - ISTITUTO ORTOPEDICO RIZZOLI - UNIVERSITY COLLEGE LONDON - DEUTSCHES KREBSFORSCHUNGSZENTRUM - FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG - - - EUR 4 949 448,90 - - - implementAtion anD OPeration of the gateway for healTh into BBMRI-ERIC - - - EUR 4 949 448,91 - - - Austria - Belgium - Switzerland - Czech Republic - Germany - Estonia - France - Greece - Netherlands - Norway - Poland - Sweden - Turkey - France - Germany - Italy - United Kingdom - Germany - Germany - - - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - - "BBMRI-ERIC: the Biobanking and BioMolecular resources Research Infrastructure - European Research Infrastructure Consortium, aims to establish, operate and develop a Pan-European distributed research infrastructure in order - to facilitate the access to biological resources as well as facilities and to support high quality biomolecular and biomedical research. - - - 2018-09-30, ongoing project | - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-3-2015 - Individual implementation and operation of ESFRI projects - - - RIA - Research and Innovation action - - - Austria - - - ADOPT BBMRI-ERIC - - - H2020-INFRADEV-1-2015-1 - - - 676550 - - - - - KING'S COLLEGE LONDON - - - EUR 183 454,80 - - - Developing new drone-based gas sensing technology to characterise fire emission plumes by miniature low cost sensors - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - This project will deliver new drone-based gas sensing technologies for environmental monitoring, specifically to characterise the complex pollution (CO, CO2, NOx, O3 etc) plumes from wildfires. It builds on the success of - these low-cost miniature sensors recently demonstrated by the ER and her industry collaborator in volcanic plumes, combined with Host expertise on fire science and remote sensing geography and partner expertise in drone applications and laboratory - sensor tests. It takes timely opportunity of a major coordinated atmospheric campaign on fire plumes. Biomass burning emissions substantially influence air quality on local to regional scales as well as global atmospheric composition. Atmospheric - modelling efforts to predict fire plume impacts require knowing the emission composition, which can vary greatly between different fires and also between different plume measurement altitudes, and temporally, depending on precise fuel makeup, degree - of smouldering vs flaming combustion, etc. Existing approaches (ground-based, aircraft, satellite) all have limitations in quantifying the emissions, near-downwind plume height and chemical evolution. Our development of new drone-based fire plume gas - sensing technology aims to fill this current ‘data gap’. There is high potential for future societal benefit through widespread applications of the new technology to detect and chemically map wildfire but also other plume hazards (e.g. volcanoes, - landfill sites, industry accident releases). - - 2019-01-08, Grant Agreement terminated - - - 2017-01-09 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - FIRE-PLUME-SENSE - - - H2020-MSCA-IF-2015 - - - 706924 - - - - - NATIONAL UNIVERSITY OF IRELAND GALWAY - GOETEBORGS UNIVERSITET - FUNDACION DE LA COMUNIDAD VALENCIANA CENTRO DE INVESTIGACION PRINCIPEFELIPE - VIB - PROTOQSAR 2000 SL - TARBIAT MODARES UNIVERSITY (INSTRUCTOR'S TRAINING UNIVERSITY) - - - EUR 607 500 - - - Exploiting Protein Complexes that Induce Cell-death - - - EUR 607 500 - - - Ireland - Sweden - Spain - Belgium - Spain - Iran - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - The formation of specific protein complexes are key events in life-and-death decisions made by cells. Inappropriate decisions underpin a plethora of disease conditions from degenerative diseases to cancer while the role of the - complexes in these processes make them important therapeutic targets. Our ability to develop small molecules to target death-inducing protein complexes has been hampered by an inability to measure complex formation in cells in real-time and by the - absence of robust high-throughput assays for the discovery of new lead molecules that target these complexes. - - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Ireland - - - EPIC - - - H2020-MSCA-RISE-2015 - - - 690939 - - - - - EUROPEAN MOLECULAR BIOLOGY LABORATORY - ABO AKADEMI - UNIVERSITY OF DUNDEE - UNIVERSITA DEGLI STUDI DI TORINO - INSTITUT CURIE - ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM - FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA) - - - EUR 1 780 585 - - - Global BioImaging Project - International imaging infrastructure services for the life science community - - - EUR 1 780 585 - - - Germany - Finland - United Kingdom - Italy - France - Netherlands - Spain - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - - "The EC H2020 funded ""Global BioImaging Project"" enables Euro-BioImaging, the research infrastructure for access to biological and medical imaging technologies on the ESFRI roadmap, to work together with its international - counterparts - the Australian Microscopy and Microanalysis Research Facility (AMMRF), the National Imaging Facility (Australia) and India-BioImaging - on concrete and sustainable services for imaging infrastructure staff and users. The project is - based on their signed collaboration agreements regarding the successful operation of imaging infrastructures to support research in the areas of biological and medical sciences. Euro-BioImaging together with the AMMRF, NIF and India-BioImaging will - exchange best practice in imaging facility management and operation, quality management, open access policies; develop and support common training activities in infrastructure operation and cutting-edge imaging technologies for facility staff and - users; develop a common virtual platform for training material on imaging technologies; develop a common virtual platform for image data analysis software. Both platforms will be openly accessible for the scientific community. - - - 2018-11-30, ongoing project | - - - 2015-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.3.2."> - - - INFRASUPP-6-2014 - International cooperation for research infrastructures - - - CSA - Coordination and support action - - - Germany - - - Global BioImaging - - - H2020-INFRASUPP-2014-2 - - - 653493 - - - - - UNIVERSITAET BERN - UNIVERSITAET BERN - - - EUR 1 915 000 - - - All-optical deconstruction of thalamic control of sleep-wake states. - - - EUR 1 915 000 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - While the functions of sleep are still a matter of debate and may include memory consolidation, brain clearance, anabolism and plasticity, the neural substrates of sleep and wake states are the subject of intense study. - Successive sleep-wake cycles rely on an appropriate balance between sleep-promoting nuclei of the brain located in the anterior hypothalamus and, arousal-promoting nuclei from the posterior hypothalamus and the brainstem. My laboratory identified - different subsets of hypothalamic cells that controls wakefulness and rapid-eye movement (also called paradoxical) sleep using optogenetics in combination with high-density electrophysiology in freely-behaving mice. We further identified their - connections with (and functional modulation of) other sleep-wake circuits throughout the brain. Although we and others have dissected important subcortical and cortical sleep-wake circuits in the brain, the precise mechanism bridging sub-cortical - circuits to thalamic and cortical networks remains unclear. - - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Switzerland - - - Opto-Sleep - - - ERC-2016-COG - - - 725850 - - - - - AGENZIA PER LA PROMOZIONE DELLA RICERCA EUROPEA - FUNDACAO PARA A CIENCIA E A TECNOLOGIA - GENIKI GRAMMATIA EREVNAS KAI TECHNOLOGIAS - DIENST VOOR WETENSCHAPPELIJKE EN TECHNISCHE INFORMATIE- SERVICE D'INFORMATION SCIENTIFIQUE ET TECHNIQUE - OESTERREICHISCHE FORSCHUNGSFOERDERUNGSGESELLSCHAFT MBH - DEUTSCHES ZENTRUM FUER LUFT - UND RAUMFAHRT EV - INSTYTUT PODSTAWOWYCH PROBLEMOW TECHNIKI POLSKIEJ AKADEMII NAUK - VEREIN EURESEARCH - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - TECHNOLOGICKE CENTRUM AKADEMIE VED CESKE REPUBLIKY - INSTITUTO DE SALUD CARLOS III - ETHNIKO IDRYMA EREVNON - - - EUR 1 996 828,50 - - - Research Infrastructures Consortium for Horizon 2020 - - - EUR 2 145 266,01 - - - Italy - Portugal - Greece - Belgium - Austria - Germany - Poland - Switzerland - France - Czech Republic - Spain - Greece - - - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Research Organisations - Other - Research Organisations - Research Organisations - Research Organisations - Research Organisations - - The National Contact Points perform valuable services in guiding and supporting national applicants in preparing proposals for Horizon 2020 funding. We expect that through an enhanced transnational cooperation and networking - between National Contact Points for research infrastructures, a higher quality of their consulting services and thus of proposals and projects can be achieved. Therefore, the specific objective of RICH (Research Infrastructures COnsortium for Horizon - 2020) is to facilitate trans-national co-operation between NCPs for research infrastructures with a view to identifying and sharing good practices and raising the general standard of support to programme applicants, taking into account the diversity - of actors that make up the constituency of the Research Infrastructures Part. - - 2018-11-30, ongoing project - - - 2014-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4."> - - - INFRASUPP-8-2014 - Network of National Contact Points - - - CSA - Coordination and support action - - - Italy - - - RICH - - - H2020-INFRASUPP-2014-1 - - - 646713 - - - - - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN - FREIE UNIVERSITAET BERLIN - UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - TECHNISCHE UNIVERSITAET WIEN - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - ECOLE NORMALE SUPERIEURE DE LYON - FORSCHUNGSZENTRUM JULICH GMBH - UNIVERSITAT DE BARCELONA - SCIENCE AND TECHNOLOGY FACILITIES COUNCIL - SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI DI TRIESTE - UNIVERSITEIT VAN AMSTERDAM - CSC-TIETEEN TIETOTEKNIIKAN KESKUS OY - SCUOLA NORMALE SUPERIORE - NATIONAL UNIVERSITY OF IRELAND GALWAY - AALTO-KORKEAKOULUSAATIO - - - EUR 4 836 895,75 - - - An e-infrastructure for software, training and consultancy in simulation and modelling - - - EUR 4 836 896,25 - - - Switzerland - Ireland - Germany - Italy - France - Austria - United Kingdom - Germany - France - Germany - Spain - United Kingdom - Italy - Netherlands - Finland - Italy - Ireland - Finland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - E-CAM will create, develop and sustain a European infrastructure for computational science applied to simulation and modelling of materials and of biological processes of industrial and societal importance. Building on the - already significant network of 15 CECAM centres across Europe and the PRACE initiative, it will create a distributed, sustainable centre for simulation and modelling at and across the atomic, molecular and continuum scales. - - - 2020-09-30, ongoing project | - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.3."> - - - EINFRA-5-2015 - Centres of Excellence for computing applications - - - RIA - Research and Innovation action - - - Switzerland - - - E-CAM - - - H2020-EINFRA-2015-1 - - - 676531 - - - - - UNIVERSITETET I OSLO - - - EUR 196 400,40 - - - Blending Stoichiometric and Metabolic Theories from Genes to Populations: Resource Stochiometry and Temperature Effects on Consumers with Contrasting Life-history Strategies - - - EUR 196 400,40 - - - Norway - - - Higher or Secondary Education Establishments - - Human-induced global warming and increased nutrient bioavailability are impacting on species evolution and ecosystem functioning worldwide. Single effects of each global change factor on consumer life history have been well - assessed by the metabolic theory of ecology, and ecological and biological stoichiometry, respectively, and for each biological level from genes to populations. However, their potential consequences when both interact remain elusive because of the - non-additive nature of their effects. STOICHIOMET project proposes to (i) study the single and interactive effects of temperature and nutrients in food on consumer performance; and (ii) test simultaneously cornerstone concepts of both metabolic - (Bergman rule) and stoichiometric theories (growth rate hypothesis; phosphorus-allocation hypothesis). To aim these, a field survey and coupled growth bioassays, following 4 (temperature) × 4 (elemental dietary composition) experimental designs, will - be conducted. Consumer growth response of selected model species (Chlamydomonas, Selenastrum, Brachionus, Diaptomus, Daphnia, Drosophila) will be measured at each level in terms of: ribosomal DNA genes and intergenic spacers; genome size; nucleic - acid and protein content; cell size; body size and elemental composition; and growth rates. Additional data treatment will be performed to model growth rate and coupled variables as functions of body size, temperature and resource stoichiometry, and - hence, theoretically integrate metabolic and stoichiometric conceptual frameworks. Multidisciplinarity of STOICHIOMET project, interrelating genetics, biochemistry, metabolism, ecology and evolution knowledge, will contribute to the scientific - development of PhD Bullejos, and together with its training programme, will favour his future re-establishment. In addition, STOICHIOMET project represents an unique opportunity to create a network among researchers from different knowledge areas and - excellent European institutions. - - 2019-01-08, ongoing project - - - 2015-10-12 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Norway - - - STOICHIOMET - - - H2020-MSCA-IF-2014 - - - 658838 - - - - - NATIONAL UNIVERSITY OF IRELAND GALWAY - MEDIZINISCHE UNIVERSITAT INNSBRUCK - LUNDS UNIVERSITET - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - DANMARKS TEKNISKE UNIVERSITET - STICHTING KATHOLIEKE UNIVERSITEIT - COLLAGEN SOLUTIONS (UK) LIMITED - ORBSEN THERAPEUTICS LIMITED - - - EUR 3 995 083,44 - - - Development of Biomaterial-based Delivery Systems for Parkinson’s disease - an Integrated Pan-European Approach - - - EUR 3 995 083,44 - - - Ireland - Austria - Sweden - France - Denmark - Netherlands - United Kingdom - Ireland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - BrainMatTrain focuses on a comprehensive understanding of Parkinson’s disease (PD), from basics to translation, fully supported by 8 full partners partner organisation (4 research institutions, 2 hospitals, 2 SMEs) and one - partner organisation (SME specialist in device design). This ETN will educate and train 15 Earlty Stage Researchers (ESRs) in functioanlised biomaterials, materials science, functionlisation strategies, molecular biology, stem cell biology, in vitro - model systems, in vivo neuroimaging, animal models and prototype design. Recruited ESRs will receive compulsory discipline-specific, generic and complementary transferable skills training. BrainMatTrain will develop multi-modal collagen reservoir - scaffolds incorporating moieties targetitng the neuroinflammatoiry and neuroprotective phases of the underlying pathology of Parkinson’s disease. The researchers will undertake cross-disciplinary and intersectorial research projects, which when - married together will deliver a novel, biomaterial-based, therapeutic device for the treatment of Parkinson’s disease. The research training programme is designed to ensure high-calibre graduates, best placed to secure employment in the private or - public sector. Fellows will experience both private and public sector research and development environments through a considered secondment plan. - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Ireland - - - BrainMatTrain - - - H2020-MSCA-ITN-2015 - - - 676408 - - - - - CENTRAL EUROPEAN RESEARCH INFRASTRUCTURE CONSORTIUM EUROPEAN RESEARCH INFRASTRUCTURE CONSORTIUM - EUROPEAN SPALLATION SOURCE ERIC - ASSOCIATION INTERNATIONALE EXTREME-LIGHT-INFRASTRUCTURE DELIVERY CONSORTIUM - KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW - TECHNISCHE UNIVERSITAET MUENCHEN - HELMHOLTZ-ZENTRUM GEESTHACHT ZENTRUM FUR MATERIAL- UND KUSTENFORSCHUNG GMBH - UZHGORODSKYI NACIONALNYI UNIVERSITET - ESP CENTRAL LIMITED - - - EUR 3 325 755 - - - ACCELERATing Europe's Leading Research Infrastructures - - - EUR 3 325 757 - - - Italy - Sweden - Belgium - Netherlands - Germany - Germany - Ukraine - United Kingdom - - - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Other - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Other - - CERIC-ERIC (CERIC) is a distributed research infrastructure for fundamental and applied research on novel materials and biomaterials. The RI has been in operation for 2 years and provides open access to a broad range of - instruments and expertise across research communities, in order to support the research community world-wide in tackling the most challenging problems of materials research. The ACCELERATE project is proposed to support CERIC sustainability through - activities of collaborative development of policies with other research infrastructures (RIs), in particular new and forming ERIC entities. ACCELERATE will assist sustainability, relevance and effectiveness of the RI through preparation of frameworks - for services to private and public entities, outreach to new scientific and industrial networks and geographical areas and a methodology for RI social impact assessment. Together with the RI partners CERIC will also carry out several intense courses - for development of future RI managerial, IL and TT staff. The project will be carried out while maintaining vigorous communication with research and industrial communities, policy makers, EC administration and other RI stakeholders. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-03-2016-2017 - Individual support to ESFRI and other world-class research infrastructures - - - CSA - Coordination and support action - - - Italy - - - ACCELERATE - - - H2020-INFRADEV-2016-1 - - - 731112 - - - - - UNIVERSITETET I OSLO - HELSINGIN YLIOPISTO - DANMARKS TEKNISKE UNIVERSITET - ABO AKADEMI - UNIVERSITAET HAMBURG - METEO-FRANCE - UNIVERSITETET I BERGEN - WAGENINGEN UNIVERSITY - - - EUR 4 073 903,28 - - - MARine MAnagement and Ecosystem Dynamics under climate change - - - EUR 4 073 903,28 - - - Norway - Finland - Denmark - Finland - Germany - France - Norway - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The proposed European Training Network, MARmaED, connects science, policy and people and transcends national borders, disciplinary barriers and sectorial divides. By building a greater knowledge base and train the next - generation of scientists to think across disciplines, MARmaED contributes to reinforce Europe’s position as a global leader in marine science and ensure blue growth and sustainable exploitation of marine living resources. - - - 2019-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Norway - - - MARmaED - - - H2020-MSCA-ITN-2015 - - - 675997 - - - - - UNIVERSITE DE BOURGOGNE - UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK - KOBENHAVNS UNIVERSITET - NATIONAL UNIVERSITY OF IRELAND GALWAY - INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE - WAGENINGEN UNIVERSITY - SYDDANSK UNIVERSITET - BIOFILM CONTROL SAS - GENXPRO GMBH - - - EUR 2 841 979,50 - - - Training and research in Listeria monocytogenes Adaptation through Proteomic and Transcriptome deep Sequencing Analysis - - - EUR 2 841 979,50 - - - France - Ireland - Denmark - Ireland - France - Netherlands - Denmark - France - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - List_MAPS is a network dedicated to the training of innovative young researchers in the field of Microbiology and Systems Biology. It focuses on Listeria monocytogenes, an ubiquitous pathogen that is in the EU the leading - cause of mortality and food recalls due to foodborne pathogens, costing the EU millions of euro per annum in medical care and associated costs in the food sector. ESRs will develop scientific expertise through PhD training, mobility of researchers, - summer schools, workshops and transfer-of-knowledge in the areas of Transcriptomics, Proteomics, Sequencing and Systems Biology. Working in this dynamic state-of-the-art field will provide for training of ESRs to the highest level, with co-operation - and movement between academia and industry that will enhance ESR training. The overall objective of the research programme is to tackle food safety through the combination of high throughput Epigenetics, Deep sequencing of transcripts, Proteomics, - Bioinformatics, Mathematics and Microbiology to decipher the transcriptional regulatory circuitry that drives adaptation and virulence of L. monocytogenes from farm to fork. This information will be exploited to understand how environmental - conditions and food composition can influence GI tract adaptation/virulence and to develop an innovative transcriptome-based tool to assess in silico the virulence of large collections of isolates. This developed tool aims at replacing the currently - used burdensome animal models. - - - 2019-02-28, ongoing project - - - 2015-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - France - - - List_MAPS - - - H2020-MSCA-ITN-2014 - - - 641984 - - - - - SCIENCE AND TECHNOLOGY FACILITIES COUNCIL - CSC-TIETEEN TIETOTEKNIIKAN KESKUS OY - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - EUROPEAN MOLECULAR BIOLOGY LABORATORY - SURFSARA BV - STICHTING EGI - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - KARLSRUHER INSTITUT FUER TECHNOLOGIE - THE UNIVERSITY OF EDINBURGH - STICHTING LIBER - TRUST-IT SERVICES LIMITED - ATHINA-EREVNITIKO KENTRO KAINOTOMIAS STIS TECHNOLOGIES TIS PLIROFOFORIAS, TON EPIKOLNONION KAI TIS GNOSIS - JISC LBG - PARTNERSHIP FOR ADVANCED COMPUTINGIN EUROPE AISBL - CONSIGLIO NAZIONALE DELLE RICERCHE - ISTITUTO NAZIONALE DI FISICA NUCLEARE - STIFTUNG DEUTSCHES ELEKTRONEN-SYNCHROTRON DESY - ISTITUTO NAZIONALE DI GEOFISICA E VULCANOLOGIA - BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION - GEORG-AUGUST-UNIVERSITAT GOTTINGENSTIFTUNG OFFENTLICHEN RECHTS - KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW - INTEGRATED CARBON OBSERVATION SYSTEM EUROPEAN RESEARCH INFRASTRUCTURE CONSORTIUM - GEANT VERENIGING - ISTITUTO NAZIONALE DI ASTROFISICA - BIOBANKS AND BIOMOLECULAR RESOURCES RESEARCH INFRASTRUCTURE CONSORTIUM (BBMRI-ERIC) - EUROPEAN SPALLATION SOURCE ERIC - NATURAL ENVIRONMENT RESEARCH COUNCIL - EUROPEAN X-RAY FREE-ELECTRON LASERFACILITY GMBH - ECRIN EUROPEAN CLINICAL RESEARCH INFRASTRUCTURE NETWORK - THE UNIVERSITY OF MANCHESTER - PIN SOC.CONS. A R.L. - SERVIZI DIDATTICI E SCIENTIFICI PER L UNIVERSITA DI FIRENZE - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - CINECA CONSORZIO INTERUNIVERSITARIO - - - EUR 9 953 067,50 - - - The European Open Science Cloud for Research Pilot Project. - - - EUR 9 953 067,50 - - - United Kingdom - Finland - Germany - Germany - Netherlands - Netherlands - France - Germany - United Kingdom - Netherlands - United Kingdom - Greece - United Kingdom - Belgium - Italy - Italy - Germany - Italy - Spain - Germany - Netherlands - Finland - Netherlands - Italy - Austria - Sweden - United Kingdom - Germany - France - United Kingdom - Italy - France - Italy - - - Research Organisations - Other - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Other - Other - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Other - Other - Research Organisations - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Research Organisations - Other - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - - The EOSCpilot project will support the first phase in the development of the European Open Science Cloud (EOSC) as described in the EC Communication on European Cloud Initiatives [2016]. - - - 2018-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-04-2016 - European Open Science Cloud for Research - - - RIA - Research and Innovation action - - - United Kingdom - - - EOSCpilot - - - H2020-INFRADEV-2016-2 - - - 739563 - - - - - UNIVERSITAETSKLINIKUM AACHEN - FORSCHUNGSZENTRUM JULICH GMBH - WEIZMANN INSTITUTE OF SCIENCE - UNIVERSITAET DUISBURG-ESSEN - SOFTWARE COMPETENCE CENTER HAGENBERG GMBH - TEL AVIV UNIVERSITY - THE UNIVERSITY OF SUSSEX - KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW - ANDOR TECHNOLOGY LIMITED - IBIDI GMBH - GRADIENTECH AB - STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS - - - EUR 3 866 665,32 - - - Research Training Network on Integrated Component Cycling in Epithelial Cell Motility - - - EUR 3 866 665,32 - - - Germany - Germany - Israel - Germany - Austria - Israel - United Kingdom - Netherlands - United Kingdom - Germany - Sweden - Netherlands - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - - Cell migration (cell motility) is a fundamental biological process that is pivotal in (i) tissue formation and repair (health) and (ii) tissue invasion during carcinogenesis (disease). Understanding and controlling cell - migration will have major clinical impact. Clarifying mechanisms driving cell motility has been challenging due to the complex underlying cellular mechanisms; these involve multiple components coordinated by structural, chemical and physical signals - in terms of time and space. To accomplish breakthroughs in this field, researchers are needed who (i) master cutting-edge experimental techniques for monitoring the different cellular processes at high resolution and (ii) have competencies in - theoretical science for integrating the resulting data sets into mechanistic mathematical models for predicting motile cell behaviour. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - InCeM - - - H2020-MSCA-ITN-2014 - - - 642866 - - - - - INSTITUTO DE ASTROFISICA DE CANARIAS - STIFTUNG KIEPENHEUER-INSTITUT FUER SONNENPHYSIK - UNIVERSITY COLLEGE LONDON - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - ISTITUTO NAZIONALE DI ASTROFISICA - UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - STOCKHOLMS UNIVERSITET - THE QUEEN'S UNIVERSITY OF BELFAST - LEIBNIZ-INSTITUT FUR ASTROPHYSIK POTSDAM (AIP) - FONDAZIONE ISTITUTO RICERCHE SOLARI LOCARNO - UNIVERSITETET I OSLO - THE UNIVERSITY OF SHEFFIELD - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - UNIVERSITA DEGLI STUDI DI CATANIA - SVEUCILISTE U ZAGREBU - GEODETSKI FAKULTET - ASTRONOMICKY USTAV AVCR VVI - ASTRONOMICAL INSTITUTE OF THE SLOVAK ACADEMY OF SCIENCES - NATIONAL OBSERVATORY OF ATHENS - UNIVERSITE PAUL SABATIER TOULOUSE III - UNIVERSITAET GRAZ - UNIWERSYTET WROCLAWSKI - EOTVOS LORAND TUDOMANYEGYETEM - - - EUR 3 998 750 - - - Preparatory Phase for the European Solar Telescope - - - EUR 9 053 638,75 - - - Spain - Germany - United Kingdom - Spain - Italy - Italy - Germany - Sweden - United Kingdom - Germany - Switzerland - Norway - United Kingdom - Ireland - Italy - Croatia - Czech Republic - Slovakia - Greece - France - Austria - Poland - Hungary - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The European Solar Telescope (EST) will be a revolutionary Research Infrastructure that will play a major role in answering key questions in modern Solar Physics. This 4-meter class solar telescope, to be located in the Canary - Islands, will provide solar physicists with the most advanced state-of-the-art observing tools to transform our understanding of the complex phenomena that drive the solar magnetic activity. The principal objective of the present Preparatory Phase is - to provide both the EST international consortium and the funding agencies with a detailed plan regarding the implementation of EST. - - 2021-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-02-2016 - Preparatory Phase and support to early phase of ESFRI projects - - - CSA - Coordination and support action - - - Spain - - - PRE-EST - - - H2020-INFRADEV-2016-2 - - - 739500 - - - - - UNIVERSITY OF GLASGOW - CHALMERS TEKNISKA HOEGSKOLA AB - AARHUS UNIVERSITET - THE UNIVERSITY OF SUSSEX - ULTRAHAPTICS LIMITED - - - EUR 2 999 870 - - - Levitation with localised tactile and audio feedback for mid-air interactions - - - EUR 2 999 870 - - - United Kingdom - Sweden - Denmark - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - "This project will be the first to create, prototype and evaluate a radically new human-computer interaction paradigm that empowers the unadorned user to reach into levitating matter, see it, feel it, manipulate it and hear - it. Our users can interact with the system in a walk-up-and-use manner without any user instrumentation. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-01-2016-2017 - FET-Open research and innovation actions - - - RIA - Research and Innovation action - - - United Kingdom - - - Levitate - - - H2020-FETOPEN-1-2016-2017 - - - 737087 - - - - - UNIVERSITETET I OSLO - KOBENHAVNS UNIVERSITET - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - UNIVERSITE LYON 1 CLAUDE BERNARD - FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG - TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY - INTERNATIONAL RESEARCH INSTITUTE OFSTAVANGER AS - - - EUR 4 103 572,68 - - - Nano-tailoring organo-mineral materials -Controlling strength and healing with organic molecules in mineral interfaces - - - EUR 4 103 572,68 - - - Norway - Denmark - United Kingdom - France - Germany - Israel - Norway - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - Cement production for the construction industry contributes up to 5% of anthropogenic CO2 emissions. Developing more environmentally friendly concrete requires the assessment of strength for a diverse range of new cement - materials. Similar issues arise during the development of biocompatible cements for medical applications. Properties of naturally cemented materials of organic origin are of key importance in the oil industry, with carbonate reservoirs prone to - creep, particularly during the injection of CO2 for enhanced oil recovery or permanent storage. However, despite the importance of cement materials to our infrastructure, health and environment, we still lack the fundamental basis for understanding - the strength of cemented aggregates. Granular pastes and sediments transform to strong solids through reactions at nano-confined mineral interfaces, where nucleation and growth at the adjacent solid surfaces are affected in a manner not yet - understood. There is a need for improved concepts, theories and models. - - - 2018-12-31, ongoing project | - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Norway - - - NanoHeal - - - H2020-MSCA-ITN-2014 - - - 642976 - - - - - KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW - ARCHIVES GENERALES DU ROYAUME ET ARCHIVES DE L'ETAT DANS LES PROVINCES - CENTRE D'ETUDES ET DE DOCUMENTATION GUERRE ET SOCIETES CONTEMPORAINES / HET STUDIE- EN DOCUMENTIECENTRUM OORLOG EN HEDENDAAGSE MAATSCHAPPIJ - ZIDOVSKE MUZEUM V PRAZE - STIFTUNG ZUR WISSENSCHAFTLICHEN ERFORSCHUNG DER ZEITGESCHICHTE - INSTITUT FUR ZEITGESCHICHTE IFZ - KING'S COLLEGE LONDON - YAD VASHEM THE HOLOCAUST MARTYRS AND HEROES REMEMBRANCE AUTHORITY - THE UNITED STATES HOLOCAUST MEMORIAL MUSEUM - BUNDESARCHIV - THE WIENER LIBRARY INSTITUTE OF CONTEMPORARY HISTORY LBG - International Tracing Service - ZYDOWSKI INSTYTUT HISTORYCZNY IM. EMANUELA RINGELBLUMA - MEMORIAL DE LA SHOAH - WIENER WIESENTHAL INSTITUT FUR HOLOCAUST-STUDIEN - VWI - ONTOTEXT AD - "INSTITUTUL NATIONAL PENTRU STUDIEREA HOLOCAUSTULUI DIN ROMANIA ""ELIE WIESEL""" - MAGYARORSZAGI ZSIDO HITKOZSEGEK SZOVETSEGE TARSADALMI SZERVEZET - INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE - VALSTYBINIS VILNIAUS GAONO ZYDU MUZIEJUS - DOKUMENTACNE STREDISKO HOLOKAUSTU OBCIANSKE ZDRUZENIE - STOWARZYSZENIE CENTRUM BADAN NAD ZAGLADA ZYDOW - FONDAZIONE CENTRO DI DOCUMENTAZIONE EBRAICA CONTEMPORANEA -CDEC - ONLUS - THE JEWISH MUSEUM OF GREECE - KAZERNE DOSSIN MEMORIAAL, MUSEUM EN DOCUMENTATIECENTRUM OVER HOLOCAUST EN MENSENRECHTEN - - - EUR 7 969 673,75 - - - European Holocaust Research Infrastructure - - - EUR 7 969 673,75 - - - Netherlands - Belgium - Belgium - Czech Republic - Germany - United Kingdom - Israel - United States - Germany - United Kingdom - Germany - Poland - France - Austria - Bulgaria - Romania - Hungary - France - Lithuania - Slovakia - Poland - Italy - Greece - Belgium - - - Research Organisations - Research Organisations - Research Organisations - Other - Research Organisations - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Other - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Other - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Other - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Other - - The European Holocaust Research Infrastructure (EHRI) project seeks to transform archival research on the Holocaust. The vision of EHRI is to integrate the data, services and expertise of existing Holocaust infrastructures on - an unprecedented scale. It will allow researchers from across the globe transnational and virtual access to the integrated infrastructure, and provide them with innovative digital tools and methods to (collaboratively) explore and analyse Holocaust - sources. EHRI will thereby become an indispensable tool for the study of the Holocaust from a pan-European perspective. - - - 2019-04-30, ongoing project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.2."> - - - INFRAIA-1-2014-2015 - Integrating and opening existing national and regional research infrastructures of European interest - - - RIA - Research and Innovation action - - - Netherlands - - - EHRI - - - H2020-INFRAIA-2014-2015 - - - 654164 - - - - - UNIVERSIDAD POLITECNICA DE MADRID - BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION - INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - SEAGATE SYSTEMS UK LIMITED - DEUTSCHES KLIMARECHENZENTRUM GMBH - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - CA TECHNOLOGIES DEVELOPMENT SPAIN SA - FUJITSU TECHNOLOGY SOLUTIONS GMBH - JOHANNES GUTENBERG-UNIVERSITAT MAINZ - - - EUR 3 803 407,92 - - - BigStorage: Storage-based Convergence between HPC and Cloud to handle Big Data - - - EUR 3 803 407,92 - - - Spain - Spain - France - Greece - United Kingdom - Germany - France - Spain - Germany - Germany - - - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - The consortium of this European Training Network (ETN) "BigStorage: Storage-based Convergence between HPC and Cloud to handle Big Data" will train future data scientists in order to enable them and us to apply holistic and - interdisciplinary approaches for taking advantage of a data-overwhelmed world, which requires HPC and Cloud infrastructures with a redefinition of storage architectures underpinning them - focusing on meeting highly ambitious performance and energy - usage objectives. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Spain - - - BigStorage - - - H2020-MSCA-ITN-2014 - - - 642963 - - - - - FORSCHUNGSZENTRUM JULICH GMBH - EUROPEAN SPALLATION SOURCE ERIC - EUROPEAN SPALLATION SOURCE ESS AB - LUNDS UNIVERSITET - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - INTEGRATED DETECTOR ELECTRONICS AS - - - EUR 3 800 932,50 - - - Solid-State Neutron Detector - A new Neutron Detector for High-Flux Applications - - - EUR 3 800 932,50 - - - Germany - Sweden - Sweden - Sweden - France - Norway - - - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The Solid-State Neutron Detector – SoNDe – project aims to develop a high-resolution neutron detector technique that will enable the construction of position-sensitive neutron detectors for high-flux sources, such as the - upcoming European Spallation Source (ESS). Moreover, by avoiding the use of 3He in this detector the 3He-shortage, which might otherwise impede the construction of such large-scale facilities, can be alleviated. The main features of the envisioned - detector technique are: - - 2019-04-30, ongoing project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-1-2014 - Design studies - - - RIA - Research and Innovation action - - - Germany - - - SoNDe - - - H2020-INFRADEV-1-2014-1 - - - 654124 - - - - - NATIONAL UNIVERSITY OF IRELAND GALWAY - - - EUR 175 866 - - - The transnational mobility of cheap print: British chapbooks in Italy, 1800-1850 - - - EUR 175 866 - - - Ireland - - - Higher or Secondary Education Establishments - - This action proposes mobility for an Italian researcher living in Britain to work in Ireland on a transnational historico-literary project. Her research focuses on the cross-cultural transfer of cheap print between Britain and - Italy in the first half of the nineteenth century. The project advances existing knowledge of popular publishing and reading in two ways. Firstly, it contributes to the European historiography of cheap publications by extending the investigation of - their production, distribution and reception to the Italian context. Secondly, and most importantly, it provides a concrete idea of the cross-cultural nature of cheap literature by exploring the mechanisms which regulate its migration from one - linguistic and cultural realm to another. The transnational trajectory of cheap print is investigated with a focus on translation and on its potential to establish fruitful negotiations between the literary and cultural repertoires of the source and - the target context. The project examines a corpus of chapbooks translated from English into Italian published between 1800 and 1850. The Italian chapbooks and their sources are analysed using an interdisciplinary approach which integrates theories of - textuality, the history of the book and of reading, and translation studies. The comparative approach followed in my study will significantly enhance our understanding of popular literature and of the processes which led to the formation of a shared - European heritage of popular culture. The multidisciplinary research environment at NUIG provides the ideal conditions for the researcher to develop this project and the skills necessary for her future academic career. The collaboration of Dr Niall Ó - Ciosáin and the training that she will undertake in the history of the book will be particularly important to integrate her familiarity with translation and the eighteenth- and nineteenth-century Italian cultural context with new knowledge of popular - publishing and reading. - - 2017-08-31, closed project | - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Ireland - - - CHAP - - - H2020-MSCA-IF-2014 - - - 660143 - - - - - NATIONAL UNIVERSITY OF IRELAND GALWAY - - - EUR 187 866 - - - Engaging Urban Youth: Community, Citizenship, and Democracy - - - EUR 187 866 - - - Ireland - - - Higher or Secondary Education Establishments - - Disadvantaged youth in urban environments often experience marginalization and disenfranchisement that can lead to disastrous consequences for them, their families, and wider society. We know that successfully engaging these - young men and women in the institutions, communities, and contexts in which they live and building their capacity as social actors can be a critical factor in their positive development as individuals and future role as citizens. Yet, there is still - relatively little known empirically about the specific contexts, strategies, and mechanisms through which disadvantaged urban youth can be most effectively engaged. This research is designed to develop the expertise of the experienced researcher to - enable him to contribute much needed in-depth knowledge of how best to engage young people as citizens both civic and political actors with autonomy and responsibility for contributing to the common good. This work will be done through a comparative - case study in three Irish cities. The methodology will involve a consultative process with designated stakeholders in each city including local politicians, policy leaders, service providers, service users, youth representatives and youth workers. It - will involve field observations and interviews with young men and women in three selected case study cities, each having a distinct urban identity: Large multi-cultural (Dublin); Post-Conflict ( Belfast) and Smaller Regional City (Galway). - Dissemination and Public Engagement are central to this proposal. The research will impact on the participating stakeholders by providing tangible and accessible research findings. It will impact on the field of urban youth studies by offering a - comparative framework applicable to other urban contexts in Europe and globally. The impact for the experienced researcher will be the development of specific expertise with a view to developing further European and global studies of this important - field. - - 2018-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Ireland - - - CMCG - - - H2020-MSCA-IF-2014 - - - 661541 - - - - - GEIE ERCIM - STICHTING CENTRUM VOOR WISKUNDE EN INFORMATICA - CONSIGLIO NAZIONALE DELLE RICERCHE - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - TECHNISCHE UNIVERSITEIT DELFT - VERENIGING EUROCRIS - ISTITUTO NAZIONALE DI GEOFISICA E VULCANOLOGIA - UNIVERSITEIT VAN AMSTERDAM - - - EUR 4 370 000 - - - A Europe-wide Interoperable Virtual Research Environment to Empower Multidisciplinary Research Communities and Accelerate Innovation and Collaboration - - - EUR 4 370 000,25 - - - France - Netherlands - Italy - Greece - Netherlands - Netherlands - Italy - Netherlands - - - Other - Research Organisations - Research Organisations - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - Higher or Secondary Education Establishments - Other - Research Organisations - Higher or Secondary Education Establishments - - The VRE4EIC project addresses key data and software challenges in supporting multidisciplinary data driven sciences. These include: - - 2018-09-30, ongoing project | - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.3."> - - - EINFRA-9-2015 - e-Infrastructures for virtual research environments (VRE) - - - RIA - Research and Innovation action - - - France - - - VRE4EIC - - - H2020-EINFRA-2015-1 - - - 676247 - - - - - NARODOWE CENTRUM NAUKI - FONDS ZUR FÖRDERUNG DER WISSENSCHAFTLICHEN FORSCHUNG - FONDS NATIONAL DE LA RECHERCHE SCIENTIFIQUE - FONDS VOOR WETENSCHAPPELIJK ONDERZOEK-VLAANDEREN - BULGARIAN NATIONAL SCIENCE FUND - MINISTRY OF EDUCATION YOUTH AND SPORTS - INNOVATIONSFONDEN - SUOMEN AKATEMIA - AGENCE NATIONALE DE LA RECHERCHE - BUNDESMINISTERIUM FUER BILDUNG UND FORSCHUNG - VDI TECHNOLOGIEZENTRUM GMBH - GENIKI GRAMMATIA EREVNAS KAI TECHNOLOGIAS - NEMZETI KUTATASI FEJLESZTESI ES INNOVACIOS HIVATAL - SCIENCE FOUNDATION IRELAND SFI - MATIMOP - THE ISRAELI CENTER FOR R&D - MINISTERO DELL'ISTRUZIONE, DELL'UNIVERSITA' E DELLA RICERCA - CONSIGLIO NAZIONALE DELLE RICERCHE - VALSTS IZGLITIBAS ATTISTIBAS AGENTURA - STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN - NORGES FORSKNINGSRAD - NARODOWE CENTRUM BADAN I ROZWOJU - FUNDACAO PARA A CIENCIA E A TECNOLOGIA - Unitatea Executiva pentru Finantarea Invatamantului Superior, a Cercetarii, Dezvoltarii si Inovarii - SLOVENSKA AKADEMIA VIED - Ministrstvo za izobrazevanje, znanost in sport - MINISTERIO DE ECONOMIA, INDUSTRIA Y COMPETITIVIDAD - VETENSKAPSRADET - SWEDISH RESEARCH COUNCIL - SCHWEIZERISCHER NATIONALFONDS ZUR FORDERUNG DER WISSENSCHAFTLICHEN FORSCHUNG - TURKIYE BILIMSEL VE TEKNOLOJIK ARASTIRMA KURUMU - THE ENGINEERING AND PHYSICAL SCIENCES RESEARCH COUNCIL - The Technology Strategy Board - OESTERREICHISCHE FORSCHUNGSFOERDERUNGSGESELLSCHAFT MBH - - - EUR 11 510 008,29 - - - QuantERA ERA-NET Cofund in Quantum Technologies - - - EUR 39 783 228 - - - Poland - Austria - Belgium - Belgium - Bulgaria - Czech Republic - Denmark - Finland - France - Germany - Germany - Greece - Hungary - Ireland - Israel - Italy - Italy - Latvia - Netherlands - Norway - Poland - Portugal - Romania - Slovakia - Slovenia - Spain - Sweden - Switzerland - Turkey - United Kingdom - United Kingdom - Austria - - - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - QuantERA ERA-NET Cofund in Quantum Technologies - - 2021-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.2."> - - - FETPROACT-03-2016 - FET ERANET Cofund in Quantum Technologies - - - ERA-NET-Cofund - ERA-NET Cofund - - - Poland - - - QuantERA - - - FETPROACT-2016 - - - 731473 - - - - - AGENCE NATIONALE DE LA RECHERCHE - FONDS ZUR FÖRDERUNG DER WISSENSCHAFTLICHEN FORSCHUNG - FONDS NATIONAL DE LA RECHERCHE SCIENTIFIQUE - BULGARIAN NATIONAL SCIENCE FUND - DEUTSCHE FORSCHUNGSGEMEINSCHAFT - INNOVATIONSFONDEN - MINISTERIO DE ECONOMIA, INDUSTRIA Y COMPETITIVIDAD - GENIKI GRAMMATIA EREVNAS KAI TECHNOLOGIAS - NEMZETI KUTATASI FEJLESZTESI ES INNOVACIOS HIVATAL - MINISTERO DELL'ISTRUZIONE, DELL'UNIVERSITA' E DELLA RICERCA - Lietuvos mokslo taryba - VALSTS IZGLITIBAS ATTISTIBAS AGENTURA - STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN - NEDERLANDSE ORGANISATIE VOOR WETENSCHAPPELIJK ONDERZOEK - NARODOWE CENTRUM BADAN I ROZWOJU - FUNDACAO PARA A CIENCIA E A TECNOLOGIA - Unitatea Executiva pentru Finantarea Invatamantului Superior, a Cercetarii, Dezvoltarii si Inovarii - VERKET FÖR INNOVATIONSSYSTEM - VETENSKAPSRADET - SWEDISH RESEARCH COUNCIL - Ministrstvo za izobrazevanje, znanost in sport - SLOVENSKA AKADEMIA VIED - TURKIYE BILIMSEL VE TEKNOLOJIK ARASTIRMA KURUMU - THE ENGINEERING AND PHYSICAL SCIENCES RESEARCH COUNCIL - - - EUR 6 052 612,50 - - - The Flagship ERA-NET - - - EUR 18 341 250 - - - France - Austria - Belgium - Bulgaria - Germany - Denmark - Spain - Greece - Hungary - Italy - Lithuania - Latvia - Netherlands - Netherlands - Poland - Portugal - Romania - Sweden - Sweden - Slovenia - Slovakia - Turkey - United Kingdom - - - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Research Organisations - Research Organisations - - FLAG-ERA, the Flagship ERA-NET, gathers national and regional funding organisation with the goal of supporting, together with the European Commission, the FET Flagship initiatives and more generally the FET Flagship programme. - Most funding organisations in Europe participate, either directly or as associated members. FLAG-ERA contributes to the construction of the two Flagship initiatives on Graphene and Human Brain research, through a range of activities such as the - launch of joint calls supporting transnational projects in synergy with the Flagships, contribution to the Flagship partnering framework, identification of potential partnering projects, information on funding opportunities for the Flagships, and - networking events. The activities in FLAG-ERA are organised around periodic events gathering all stakeholders and structured in sessions dedicated to the various objectives and related tasks of the project. FLAG-ERA II is the second ERA-NET project, - implemented as an ERA-NET Cofund, starting in December 2016 for a period of 5 years, following the first FLA-ERA ERA-NET project which lasted from October 2013 to November 2016. - - 2021-11-30, ongoing project - - - 2016-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.3."> - - - FETFLAG-01-2016 - Partnering environment for FET flagships - - - ERA-NET-Cofund - ERA-NET Cofund - - - France - - - FLAG-ERA II - - - H2020-FETFLAG-01-2016 - - - 730027 - - - - - BCAM - BASQUE CENTER FOR APPLIED MATHEMATICS - - - EUR 158 121,60 - - - Derivation of Effective Dynamics from Microscopic Evolution Equations - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - The derivation of macroscopic (effective) equations from microscopic considerations is a long-standing challenge of the mathematical analysis of many-body problems. In this research proposal, we focus on the derivation of - (linear or non-linear) kinetic and Hartree-type equations from microscopic quantum models. - - - 2017-05-31, closed project | - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - DEDMEE - - - H2020-MSCA-IF-2014 - - - 660021 - - - - - UNIVERSITE DE PARIS-SORBONNE (PARIS IV) - - - EUR 173 076 - - - The dawn of writing in Western Mediterranean: a comparative approach to the Iberian epigraphic corpus - - - EUR 173 076 - - - France - - - Higher or Secondary Education Establishments - - This project proposes a study of all known Iberian inscriptions (about 2.000 documents dating from the 5th century BC to the 1st century AD) in a comparative and interdisciplinary perspective. The study of the Iberian corpus - will be set in a broad cultural context, including the rise of the first Western written traditions and their linguistic and cultural contacts. I will focus on issues such as the relationship between text and object, the Iberian adoption of exogenous - epigraphic models (mainly Phoenician/Punic, Greek and Latin), and the level of literacy within the male and female spheres of this society. - - 2017-09-14, closed project - - - 2015-09-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - ZEPHYROS - - - H2020-MSCA-IF-2014 - - - 655938 - - - - - UNIVERSITETET I OSLO - - - EUR 208 400,40 - - - Bacterial Adhesion Control through Surface TArgeted Regulation - - - EUR 208 400,40 - - - Norway - - - Higher or Secondary Education Establishments - - Fundamental investigations of bacterial adhesion will create the knowledge base to advance surface engineering approaches. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Norway - - - BAC-STAR - - - H2020-MSCA-IF-2015 - - - 704903 - - - - - NATIONAL UNIVERSITY OF IRELAND GALWAY - - - EUR 175 866 - - - The Application of Advanced Raman Spectroscopies to the Quantitative Analysis of Industrial Chromatography Columns - - - EUR 175 866 - - - Ireland - - - Higher or Secondary Education Establishments - - Dr. Kevin Buckley (KB) was awarded his PhD from University College London (UCL) in 2011. At UCL he had worked to develop Raman spectroscopy as a tool for bone-disease diagnosis and he subsequently took a position as a Laser - Spectroscopy Scientist, at the Rutherford Appleton Lab (RAL) in Oxfordshire, England, to continue this work. After leaving RAL, KB moved to the University of British Columbia (UBC) in Vancouver, Canada. At UBC he worked to develop a Raman - spectroscopy-based instrument for detecting chemical changes in (donated) human red blood cells as they age in plastic blood-bags. He has recently (Aug 2015) returned to his home country of Ireland and the primary aim of the proposed Marie - Skłodowska-Curie Fellowship is to reintegrate him with the research community there. The primary scientific objectives of the fellowship to develop novel analytical methods based on Spatially Offset Raman Spectroscopy (SORS) for applications in - biopharmaceutical manufacturing. It is proposed that this interdisciplinary research take place under the supervision of Dr. Alan Ryder (AR) in the Nanoscale Biophotonics Lab (NBL) at the National University of Ireland, Galway. The combination of - KB’s SORS expertise with AR’s biopharma expertise has the potential to deliver innovative science; KB is one of the few researchers in the world who has years of experience with SORS of complex materials (he trained under the inventor of SORS, Prof. - P. Matousek FRSC, at RAL) and AR is an international leader in the development of quantitative analytical methods for biopharmaceutical manufacturing processes. In addition to scientific objectives, the fellowship programme has been designed to - develop KB’s career and enhance his ability as a scientist. He will be provided with opportunities to develop academic teaching skills and will prepare a specific career development strategy. AR will also mentor KB as he prepares post-fellowship - grant proposals and begins his independent academic career. - - 2018-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Ireland - - - RICC - - - H2020-MSCA-IF-2015 - - - 705249 - - - - - THE UNIVERSITY OF SUSSEX - - - EUR 195 454,80 - - - Structural and Functional Studies of ATRX- Syndrome Protein - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The eukaryotic genome is packaged into chromatin, which needs to be unpacked to provide necessary access by cellular factors for varied cellular functions. However, DNA can be rendered accessible by the action of - energy-consuming chromatin remodelling proteins. One such protein is ATRX that harbours an N-terminal plant homeodomain (PHD) and a C-terminal helicase domain that confers ATPase activity and identifies ATRX as a member of the snf2 family member of - chromatin remodellers. ATRX has been shown to localize in vivo with constitutive heterochromatin in pericentromeric regions as well as telomeres where it works in complex with DAXX for the deposition of the Histone3.3. Mutations in the ATRX gene give - rise to ATR-X syndrome, a severe X-linked mental retardation syndrome often accompanied by alpha-thalassemia. Mounting evidence links ATRX mutations to cancer and to malignancies that depend on a telomerase-independent pathway of telomere maintenance - called the ‘alternative lengthening of telomeres (ALT) pathway, linking ATRX to aging. Despite these advances however, there is lack of understanding of the molecular mechanism of ATRX and of its role within these pathologies. The proposed research - aims to investigate the structural and functional properties of ATRX, and to define at a molecular level how it interacts with DAXX to remodel chromatin. We will use a combination of biophysical techniques like NMR, Isothermal Calorimetry and western - blotting to characterize ATRX interaction with partner proteins. X-ray crystallography, Cryo-electron microscopy and Small angle X-ray scattering techniques will be used to elucidate the structure of ATRX complexes. We will also design assays to - measure the enzymatic activity of the ATRX snf2 domain by itself and in presence of DNA and/or its interacting partners. These studies will provide insight into a potential new mechanism of chromatin remodelling and will help us elucidate the - consequences of disease-related ATRX mutations. - - 2017-08-31, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SFSASP - - - H2020-MSCA-IF-2014 - - - 660349 - - - - - THE UNIVERSITY OF SUSSEX - - - EUR 183 454,80 - - - Faking It: The production, perception, and function of social voice modulation - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The human voice is a social tool. Non-linguistic voice cues can influence judgements of attractiveness, formidability, trustworthiness, intelligence, and general likeability, with meaningfully differential social outcomes - depending on whether ones voice is credited, unduly or not, with positive or negative attributes. Yet, despite its apparent societal implications and the known capacity for vocal control, studies of human voice perception have focused on static - rather than dynamic speech. The proposed project will explore the vastly understudied niche of human voice modulation. The Research Objectives of the project are to: (1) Provide the first experimental evidence of voice modulation in four novel social - contexts (political debate, commercial ad, public lecture, and first date); (2) Describe the structure and production mechanisms of modulated speech using new technology developed through a secondment; (3) Identify individual and environmental - factors that affect the use and nature of modulated speech; (4) Test the extent to which voice modulation effectively influences social attributions and decisions. The project will be the first to examine voice modulation across cultures, addressing - a serious need for comparative research in psychology, and facilitating international collaboration. The research objectives will be achieved through a unique combination of lab and field voice recordings, spectrotemporal speech analysis, - questionnaire data, cross-cultural and cross-linguistic playback experiments, and sophisticated statistical modelling. This original line of research will provide ample insight into how the voice affects human behaviour, ultimately helping to uncover - the functions and origins of nonverbal communication, but also educating lay and scientific communities about social stereotyping and its socioeconomic impact. Importantly, the Fellowship will put me in an excellent position to secure a research - station in one of the top European universities. - - 2018-01-31, closed project - - - 2016-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - Voice Modulation - - - H2020-MSCA-IF-2014 - - - 655859 - - - - - UNIVERSITAET ZU KOELN - - - EUR 171 460,80 - - - Freedom of Teaching and Political Control:The Case of Thomas Aquinas’ Assimilation in William of Peter Godin’s Lectura Thomasina (14th C.) - - - EUR 171 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - The project intends to explore the speculative, historical, and political functions assumed by William of Peter Godin’s Lectura thomasina in the assimilation and teaching of Thomas Aquinas’ doctrines after the series of - condemnations, censures, and corrections promulgated by some political authorities between the end of the 13th and the beginning of the 14th century. The text, still unpublished and preserved in fifteen manuscripts, does not represent a mere - collection of Thomas’ dicta, but rather a sort of authorized handbook for students, which frequently replaced the direct lecture of Aquinas’ texts. In line with the educational policies, but true to Thomas’ intentions, the Lectura thomasina is an - outstanding multidisciplinary document: it harmonizes speculative contents from Thomas Aquinas’ texts with political pressures and religious convinctions. - - 2017-05-14, closed project - - - 2015-05-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - TEACHPOL - - - H2020-MSCA-IF-2014 - - - 657033 - - - - - UNIVERSITE DE PARIS-SORBONNE (PARIS IV) - - - EUR 185 076 - - - Literature against anti-Semitism (1940-1944). French and Soviet emigré writers in France against the persecution of the Jews - - - EUR 185 076 - - - France - - - Higher or Secondary Education Establishments - - The research project Literature against anti-Semitisme (1940-1944). French and Soviet emigré writers in France against the persecution of the Jews aims at investigating the views which writers had of the persecution of the - Jews in Occupied France. More exactly, it aims at approaching the texts of the writers who reacted to the injustices suffered by the Jews who became exiles and were hunted down as Others, before being simply eliminated. In this context, we intend to - study various works of fiction (stories, novels, poetry) in which the question of the persecution of the Jews is at stake. The project is defined by two axes: (1) the French writers who raised their voices against the persecutions of which the Jews - were victims in France, (2) émigré writers from Central and Oriental Europe (Russian, Russian-language, Georgian) who lived in France during the Occupation and who also stood up against these injustices. - - - 2017-05-31, closed project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - LIAGAN - - - H2020-MSCA-IF-2014 - - - 652978 - - - - - EUROPEAN SPALLATION SOURCE ERIC - EUROPEAN SPALLATION SOURCE ESS AB - CESKE VYSOKE UCENI TECHNICKE V PRAZE - KOBENHAVNS UNIVERSITET - TEKNOLOGISK INSTITUT - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - INSTITUT MAX VON LAUE - PAUL LANGEVIN - FORSCHUNGSZENTRUM JULICH GMBH - MAGYAR TUDOMANYOS AKADEMIA WIGNER FIZIKAI KUTATOKOZPONT - ELETTRA - SINCROTRONE TRIESTE SCPA - ISTITUTO NAZIONALE DI FISICA NUCLEARE - TECHNISCHE UNIVERSITEIT DELFT - CONSORCIO PARA LA CONSTRUCCION, EQUIPAMIENTO Y EXPLOTACION DE LA SEDE ESPANOLA DE LA FUENTE EUROPEA DE NEUTRONES POR ESPALACION - LUNDS UNIVERSITET - MITTUNIVERSITETET - PAUL SCHERRER INSTITUT - SCIENCE AND TECHNOLOGY FACILITIES COUNCIL - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH - DANMARKS TEKNISKE UNIVERSITET - - - EUR 19 941 964 - - - Building a research infrastructure and synergies for highest scientific impact on ESS - - - EUR 19 941 964 - - - Sweden - Sweden - Czech Republic - Denmark - Denmark - France - France - Germany - Hungary - Italy - Italy - Netherlands - Spain - Sweden - Sweden - Switzerland - United Kingdom - Switzerland - Denmark - - - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Jiri Matas - Tel.: +420 22435721 - Fax: +420 224357385 - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - - The science of materials has always been at the centre of scientific and technological progress in human development. The tools to understand materials that fashion them to meet our societal needs have been just as important. - Thermal neutrons are one of the most powerful probes that look directly at the structure and dynamics of materials from the macro- to the microscopic scale and from nano-seconds to seconds. It is therefore natural that a group of 17 European Partner - Countries have joined together to construct the world’s most powerful neutron source, the European Spallation Source (ESS). The importance of ESS has been recognised by ESFRI who have prioritised it as one of three Research Infrastructures (RIs) for - this INFRADEV-3 call. However, simply constructing the most powerful spallation neutron source will not, by itself, ensure the maximum scientific or technological impact. What is needed is an integrated program that ensures that key challenges are - met in order to build an ESS that can deliver high impact scientific and technological knowledge. With a timeline of 36 months, involving 18 Consortium Partners and a budget of € 19.941.964, the BrightnESS proposal will ensure that (A) the extensive - knowledge and skills of European companies, and institutes, are best deployed in the form of In-Kind Contributions to ESS for its construction and operation, (B) that technology transfer both to, and from, the ESS to European institutions and - companies is optimised and, (C) that the maximum technical performance is obtained from the ESS target, moderators and detectors in order to deliver world class science and insights for materials technology and innovation. - - 2018-08-31, ongoing project | - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-3-2015 - Individual implementation and operation of ESFRI projects - - - RIA - Research and Innovation action - - - Sweden - - - BrightnESS - - - H2020-INFRADEV-1-2015-1 - - - 676548 - - - - - UNIVERSITY OF CENTRAL LANCASHIRE - - - EUR 195 454,80 - - - Black Women/Black Nationalism – Feminist Discourses on Nation-building in American and British Literature and Visual Arts - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - My research aims to make a significant contribution to the scholarship on contemporary Black women artists in the US & the UK. It will pose a polemical formulation of Black feminist literature and visual arts of the 1980s - and 90s in light of postcolonial scholarship. These two decades saw a flowering of talent of Black British and American women: in the US they are described as Black Women’s Renaissance and in the UK as Black Arts Movement. Both movements came to - fruition in the aftermath of civil rights and feminist struggles of black people in the US and UK. This project will investigate how the work of African American and Black British female artists reflected interaction and intersection of cultural - nationalism and black feminism. It will demonstrate that feminist narratives and artworks of that period, usually not associated with black cultural nationalism, played a pivotal role in the continuation of indigenous cultural politics of Black - cultural nationalism, which came to being in the 1960s and 70s in the US. During that period African American art strove to validate black culture as a culture possessing its own ideas and forms of aesthetic expression. The cause of BCN was propelled - through the veneration of Black values, sensibilities, symbols, and rituals, which, as this project will argue, became also central to the identity politics of the artists of Black Women Renaissance and Black Arts Movement in the decades that - followed. My project will demonstrate that this strategy of validating black culture, which was so empowering in the 1960s and 70s, ultimately turned to be counter-productive for the goals of black feminism, as it created a limited number of - positions from which black women’s subjectivity could be articulated. UCLan with its world-class researchers in transatlantic studies (i.e. Prof. Rice) and Black Arts and black feminism (i.e. Prof. Lubaina Himid, a founder of Black Arts Movement) - provides an ideal host institution. - - 2018-07-31, ongoing project - - - 2016-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - BWBN - - - H2020-MSCA-IF-2015 - - - 706741 - - - - - UNIVERSITAET ZU KOELN - - - EUR 159 460,80 - - - Characterising plant interactions with bacteria that promote the uptake of nitrogen and sulphur from organic sources - - - EUR 159 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - The plant rhizosphere contains an abundant and diverse array of microbes, and plants interact with this microbial community in diverse ways, from mutualistic to neutral to pathogenic. It is proposed that future agricultural - systems should strategically incorporate mutualistic plant-microbe associations, whereby high-performing combinations of plant genotypes and microbial populations are co-cultivated to promote improved nutrient use efficiency and decreased fertiliser - application. Currently, there is a poor scientific understanding of the precise biochemical transformations and exchanges that occur in mutualistic associations between plants and microbes, and it is also unclear which specific microbial species are - the most effective for supporting plant growth and nutrition. There is evidence that plant genotypes exhibit differing capacities to shape their rhizospheric microbiome , but our poor mechanistic understanding of this phenomenon prevents breeding - strategies to select crop varieties that will host favourable microbial interactions. Therefore, this project proposes to address these gaps in scientific knowledge, by undertaking co-cultivation experiments that investigate which specific bacterial - species are most effective for enhancing plant uptake of nitrogen (N) and sulphur (S) from organic sources, as well as which specific Arabidopsis accessions are the most receptive hosts for these interactions. Next, isotope labelling and metabolic - flux studies will be undertaken in the best and worst performing plant-microbe combinations, to define the specific biochemical routes of N & S transfer that are favourable for plant nutrition. Also, genetic investigations will be undertaken to - find the key genes responsible for favourable plant-microbe interactions. This project combines the complementary expertise of its participants to deliver high-quality training to the researcher, which will enhance his professional maturity in this - strategically important field. - - 2018-06-30, ongoing project - - - 2016-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - PINBAC - - - H2020-MSCA-IF-2015 - - - 705808 - - - - - THE UNIVERSITY OF SUSSEX - - - EUR 195 454,80 - - - Plant resilience and floral adaptation to pollinator change during a range expansion - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Interactions among plants and floral visitors determine the outcome of many important processes, such as pollination, plant reproductive success and, in the longer term, plant evolution. Recent evidence shows human-induced - pollinator declines and in consequence plants are experiencing new “pollinator environments”. These changes can be detrimental to plant populations, or alternatively, they could be resilient by adapting to the new environments. This project will use - a multidisciplinary combination of field studies and genome sequencing to investigate the resilience and potential for evolutionary change of plant populations when faced with changes in pollinators. For this I will use the recent large-scale range - expansion of a European insect-pollinated herb, Digitalis purpurea, as a natural experiment to compare pollinators, floral traits, and estimates of heritability in native versus naturalised populations in the New World. The naturalised populations - are pollinated by different animals, and could harbour lower genetic variation. Dense molecular marker panels will be used to estimate heritability in the field. The results will provide important insight into 1) the evolution of plant traits in - conditions that could favour innovative change, and 2) the consequences of human-induced environmental changes on plant and pollinator populations in the long term. The main novelty is the combination of the study of changed natural selection regimes - with the estimation of trait heritability in the same wild populations. This project will increase my competitiveness for academic consolidation through training a critical period in my career. Working at the University of Sussex will provide - excellent training in insect evolution and conservation, bioinformatics, and teaching and mentoring students in a top-class research environment. In turn, I will contribute my knowledge on plant biology through teaching and collaborations in a mostly - animal-oriented group. - - 2018-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - FLORADAPT - - - H2020-MSCA-IF-2015 - - - 706365 - - - - - NATIONAL UNIVERSITY OF IRELAND GALWAY - - - EUR 175 866 - - - Genome surveillance by small non-coding RNAs - - - EUR 175 866 - - - Ireland - - - Higher or Secondary Education Establishments - - Water, oxygen, and sunlight are essential to most forms of life, yet they also represent a challenging environment for the genetic material as they drive reactions that lead to damage of DNA. To ensure cell survival, an - elaborate response to DNA damage maintains genome integrity. Until recently, the DNA damage response (DDR) was described as a wave of protein posttranslational modifications that signal the presence of DNA damage to the cell and mobilize enzymatic - repair pathways. Recently, genome-wide screens and advances in next-generation sequencing (NGS) shed light on the role of RNA-binding proteins and non-coding RNAs (ncRNAs) in the DDR. A novel class of small ncRNAs produced from the vicinity of DNA - double strand breaks (DSB) – DNA damage-inducible ncRNAs (diRNAs) - were identified in plants, flies, and mammals. Our understanding of the biogenesis of diRNAs and their role in DSB repair is currently limited by the lack of methods for their - detection that can be implemented in every laboratory. The aim of this project is to close this technological gap by developing robust and versatile methods of analysis of diRNA biogenesis. Our original approach consists to map diRNAs using NGS - technology at site-specific DSBs inducible by an endonuclease, and to create the first database of human diRNAs. The knowledge of the sequences of diRNAs will allow us to develop methods for detection of both precursor and mature diRNAs. To identify - novel players of the diRNA biogenesis pathway, we will perform a small-scale siRNA-based screen of RNA-binding proteins using the developed methods. This study will lead to important technological and knowledge-based developments in the DDR field, - and to a better understanding of how the “non-coding” genome regulates important cellular functions. - - 2018-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Ireland - - - GSR - - - H2020-MSCA-IF-2015 - - - 706828 - - - - - UNIVERSITE DE PARIS-SORBONNE (PARIS IV) - - - EUR 173 076 - - - Ancient Egypt’s Wine Rebirth - - - EUR 173 076 - - - France - - - Higher or Secondary Education Establishments - - The present paradigm on wine history states that viticulture is originated in the Near East and that Europe’s wine culture is a Greek and Roman heritage. The Egyptian wine culture is one of the world’s most ancients, however, - the extensive archaeological evidences have not been fully investigated. - - 2018-05-31, ongoing project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - EGYWINE - - - H2020-MSCA-IF-2015 - - - 699858 - - - - - UNIVERSITETET I OSLO - - - EUR 208 400,40 - - - Unraveling the ecology of a widespread fungal group by genomic, isotopic and physiological analyses - - - EUR 208 400,40 - - - Norway - - - Higher or Secondary Education Establishments - - This proposal aims to shed light on the life strategy of Mycena (or bonnet mushrooms), a widespread group of macrofungi and with important functions in forests and other terrestrial ecosystems. While its members have - traditionally been uniformly assumed to be degraders of litter, wood and other dead biological matter, very recent research has suggested that several members could in fact be parasitically or mutualistically biotrophic with plants. In numerous - studies, environmental sequences with affinity to Mycena have been observed associated with plant roots. To solve this puzzle, we will use a multifaceted, interdisciplinary approach where we combine traditional knowledge about fungal cultivation with - advanced DNA sequencing technology and isotope analyses techniques. The rapidly developing high throughput DNA sequencing technology (HTS) produces millions of DNA strands within hours, and by applying this to plant roots, we will quickly obtain an - overview of the presence of Mycena in or on plant roots (indicating a possible biotrophic relationship). We will create a database of Mycena sequences from our own sequencing as well as sequences already publicly available. By sequencing the entire - genome of five carefully selected species of Mycena, we will be able to analyse the genomic content associated with different life strategies. As molecular identification of Mycena associated with plant roots does not indicate an ecological - interaction per se, we will employ innovative research techniques designed to quantify potential interactions. Isotopic fractionation of carbon/nitrogen of Mycenas and plants at field sites can reveal the mushroom´s source of carbon, and co-culturing - of biotrophic Mycenas together with plants will provide direct evidence for the nature of their relationship(s). This research will clarify the ecology of a prominent and widespread genus of fungi, thereby illuminating its role in forest and general - plant ecology. - - 2017-07-31, closed project - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Norway - - - Mycena - - - H2020-MSCA-IF-2014 - - - 658849 - - - - - NATIONAL UNIVERSITY OF IRELAND GALWAY - NATIONAL UNIVERSITY OF IRELAND GALWAY - - - EUR 1 477 622 - - - Immune Response and Social Cognition in Schizophrenia - - - EUR 1 477 622 - - - Ireland - Ireland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Schizophrenia, affecting 0.5-1% of the population, is ranked by the World Health Organisation as more disabling than paraplegia or blindness in 18-34 year olds. Current treatments, developed over 50 years ago, are only partly - effective in treating this disability, and new treatments are lacking. To address this treatment impasse, this project aims to develop and test a novel immune based model of deficits in social cognition – the set of mental operations that underlie - social interactions (e.g. emotion recognition, theory of mind) and strongly predict social disability in schizophrenia. Based on recent discoveries in schizophrenia genetics, this project asks: (1) are genetic causes of deficits in social cognition - mediated by effects on immune function during development and (2) does early social environment moderate these effects? To address these questions, the project has two parts. Part A focuses on neuropsychological and neuroimaging studies of social - cognition in patients and healthy adults so as to (1) provide an innovative characterisation of the effects of inflammatory markers (e.g. pro-/anti- inflammatory cytokines) on social cognition, (2) establish whether these markers mediate the effects - of recently identified genetic risk loci on schizophrenia, and (3) identify to what extent early social environment (e.g. parental relationships, childhood trauma) moderates this relationship. Part B focuses on behavioural and pharmacological studies - in mice to (1) establish the causal effects of early immune challenge and early social environment on social cognition, and (2) test the translational benefits of anti-inflammatory treatment to normalize the resulting deficits. By validating an - immune based model of schizophrenia, this project has the potential to move beyond current (dopamine based) treatments, and suggest groundbreaking alternatives for understanding and treating social disability in this and other neurodevelopmental - disorders. - - 2021-06-30, ongoing project - - - 2016-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Ireland - - - iRELaTE - - - ERC-2015-STG - - - 677467 - - - - - NATIONAL UNIVERSITY OF IRELAND GALWAY - - - EUR 187 866 - - - Real-time diagnostics for Enabling Advanced laser-based roll to roll materials Processing - - - EUR 187 866 - - - Ireland - - - Higher or Secondary Education Establishments - - An experienced researcher with laboratory expertise in real time monitoring of laser-matter-ambient-interactions will be diversified towards scalable production which is desperately needed to fully realise the potential of - high repetition rate, multi-kiloWatt, femtosecond and picoseconds laser technologies. The fabrication of integrated multifunctional thin film devices by additive (inkjet, spray) and subtractive (laser) manufacturing on Roll to Roll (R2R) production - platforms is also suddenly possible and desperately needed to transform the competitiveness of Europe’s SME manufacturing sector. The training programme will lead to scalable innovation by developing diagnostics for ultra-precision laser processes. - The initial objective of the project is to identify which intersecting value chains for real time or in-line diagnostics can fully realise the potential of short pulse laser structuring. Three diagnostics based on gated (i) spectral analysis of laser - generated plasma plumes, (ii) image analysis of laser material ambient interactions and (iii) laser induced breakdown spectroscopy will be developed. The Fellow will demonstrate two process diagnostics using the R2R pilot line at the industry site. - The application of these on-line tools will create pathways for cost effective production based on new nano-inspired materials relevant to flexible large area electronics. The multi-partner training environment provides excellent facilities for the - talented ambitious Fellow. Over 30+ researchers will be directly impacted by the project. An active programme of knowledge transfer and information dissemination is also proposed based on industrial workshop, active conference participation, journal - publications, and science promotion. - - 2017-06-30, closed project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Ireland - - - REAP - - - H2020-MSCA-IF-2014 - - - 659454 - - - - - UNIVERSITY OF CENTRAL LANCASHIRE - - - EUR 195 454,80 - - - MILK BANKING AND THE UNCERTAIN INTERACTION BETWEEN MATERNAL MILK AND ETHANOL - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Donor human milk banks are expanding around the world at an exponential rate, which is directly linked to global increases in premature births. The importance of human milk for prematurely born infants has been extensively - identified, even among the recent social scientific work that has questioned the efficacy of human milk and health considerations. In addition, research also shows that a significant percentage of these mothers, at least initially, experience - lactation problems. Europe is taking a leadership role in expansion of human milk banks, although issues associated with alcohol consumption and maternal donations are a concern for clinicians and health care staff, given the increasing problems - associated with drinking among women of childbearing age. Europe with the highest alcohol per capita consumption rates in the world, makes these issues particularly immediate. The United Kingdom (UK) with its long history and current global - leadership role is an ideal place to study these considerations which will inform these larger issues of human milk for the prematurely born infant. A leader in this century old intervention, supporting not only one of the oldest hospital based banks - in Europe, but also an important cross-border collaborations on the island of Ireland, along with a research based national bank in Scotland, each representing different cases contributing significantly to the re-birth of the medical control of human - milk. The UK is poised to offer the world vital information regarding donor human milk banking, maternal bodies and ‘trust’, an important sociological social theoretical concept which will be used to frame the triangulated data collected for this - project (including interviews, archival data, and ethnographic information). Supporting an excellent experienced female researcher to return to the academy following a maternity/career break, this project directly supports women and science in - society. MUIMME is an old Irish word for wet-nurse. - - 2017-03-31, closed project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - United Kingdom - - - MUIMME - - - H2020-MSCA-IF-2014 - - - 654495 - - - - - UNIVERSITETET I OSLO - - - EUR 196 400,40 - - - Hybrid Particle-Field Approach Including Electrostatics for Large-Scale Simulations of Biological Systems - - - EUR 196 400,40 - - - Norway - - - Higher or Secondary Education Establishments - - Despite the continuous progress in computer simulations, the typical time and size bottlenecks are nowadays still heavily affecting the feasibility of large-scale simulations of complex biological systems at the molecular - resolution accuracy. The current proposal aims at formulating a new hybrid particle-field approach including explicit treatment of electrostatic interactions for computational modelling of complex biological environments. The proposed method will - combine the computational advantages of a self-consistent field approach (linear scaling cost for computation of intermolecular interactions, easy parallelization), becoming increasingly popular in polymer and soft-matter simulations, with a rigorous - treatment of particles and explicit electrostatics. The proposed approach will allow fast and reliable simulations of polyelectrolyte mixtures, including biological charged membranes, multi-phase systems, and biological polymers (polysaccharides, - proteins, nucleic acids etc), and it will make it possible to break by orders of magnitude the current limits for biomolecular simulations both in time and size. The project will have a main development part, where the self-consistent field formalism - with electrostatics will be derived and implemented, and an applicative part, where the new methodology will be tested on lipopolysaccharide moieties. These large amphiphilic and chemically complex molecules constitute the outer membrane of Gram- - bacteria, and are to date one of the major research targets to in antibiotic resistance studies. This project is multidisciplinary and involves international collaboration. This project would have a great positive impact on the applicant’s early - stage researcher career, identifying her as one of the key players in the opening a new pathway into molecular simulations of biological systems. - - 2018-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Norway - - - HYPERBIO - - - H2020-MSCA-IF-2015 - - - 704491 - - - - - UNIVERSITETET I OSLO - UNIVERSITETET I OSLO - - - EUR 1 499 439 - - - Effects of Medication Use in Pregnancy on Infant Neurodevelopment - - - EUR 1 499 439 - - - Norway - Norway - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Currently, thousands of pregnant women in the EU and worldwide are being increasingly prescribed medications for which we do not have sufficient information on fetal safety. I hypothesize that our current understanding of - safety pharmacology is oversimplified and that medication prescribed during pregnancy may play an unrecognized role in the development of neurodevelopmental disorders. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Norway - - - DrugsInPregnancy - - - ERC-2014-STG - - - 639377 - - - - - UNIVERSITAET ZU KOELN - UNIVERSITAET ZU KOELN - - - EUR 1 488 048 - - - The radiative interstellar medium - - - EUR 1 488 048 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The pressure, radiation, and ionization from the warm (UV emitting) and hot (X-ray emitting) gas has a significant impact on the cold, star-forming interstellar medium. We propose to carry out a comprehensive 3D study of the - turbulent, multi-phase ISM in different environments that includes, for the first time, a proper treatment of UV and X-ray emission from stellar (primary) sources and extended (secondary) sources like cooling shock fronts and evaporating clouds. We - do this by means of massively parallel, high-resolution 3D simulations that capture the complex interplay of gravity, magnetic fields, feedback from massive stars (ionizing radiation, radiation pressure, stellar winds, supernovae), heating and - cooling including X-rays and cosmic rays, and chemistry. We are developing a novel, original and highly efficient method to accurately treat the transfer of radiation from multiple point and extended sources in the 3D simulations. Radiation and - chemistry will be coupled to achieve self-consistent heating, cooling, and ionization rates. Moreover, accurate synthetic observations covering the large dynamic range from X-rays down to radio emission will be generated to set the results in the - proper observational context. This will enable us to address the key science questions: How efficient is stellar feedback in different environments and which feedback process is dominant? What is the precise role of UV radiation and X-rays, also from - secondary sources? Are the observations following the key dynamical players? How do we best interpret ISM observations from ALMA, SKA, or ATHENA? How do we assist in designing future observations? With the resources requested here we will perform the - most self-consistent theoretical study of the multi-phase ISM so far, thus building up a leading group for ISM research in Europe. To stimulate worldwide scientific activities and interactions we will make all data available to the community through - an open-access web interface. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - RadFeedback - - - ERC-2015-STG - - - 679852 - - - - - THE UNIVERSITY OF SUSSEX - THE UNIVERSITY OF SUSSEX - - - EUR 1 494 865 - - - Sensory Experiences for Interactive Technologies - - - EUR 1 494 865 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The senses we call upon to interact with technology are still very limited relying mostly on visual and auditory senses. The grand challenge and vision of this project is to gain a rich and integrated understanding on touch, - taste, and smell experiences for interactive technologies. - - 2020-03-31, ongoing project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - SenseX - - - ERC-2014-STG - - - 638605 - - - - - THE UNIVERSITY OF SUSSEX - THE UNIVERSITY OF SUSSEX - THE UNIVERSITY OF LIVERPOOL - - - EUR 1 000 565 - - - Sexual Orientation and Gender Identity Claims of Asylum: A European human rights challenge - - - EUR 1 000 565 - - - United Kingdom - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project will generate the first ever theoretically and empirically-grounded comparative and comprehensive picture of the status and legal experiences of asylum-seekers across Europe claiming international protection on - the basis of their sexual orientation or gender identity (SOGI), and determine how the European asylum systems can treat more fairly asylum claims based on the claimant’s SOGI. Every year, thousands of individuals claim asylum in Europe based on - their SOGI, and more often than not their claims are treated unfairly, especially considering the disproportionately high rate of refusals on these grounds. There have been very limited attempts to address this issue, and this research will overcome - this gap by carrying out a study more comprehensive than any other done in this field in the past, and producing outcomes that are unparalleled in terms of their reach. - - - 2020-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - SOGICA - - - ERC-2015-STG - - - 677693 - - - - - UNIVERSITAET ZU KOELN - UNIVERSITAET ZU KOELN - - - EUR 1 928 750 - - - Many-body physics and superconductivity in 2D materials - - - EUR 1 928 750 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The goal of this project is to prepare and functionalize layered materials and then to characterize them in-situ using a novel combination of electrical transport, photoelectron and optical spectroscopy. This approach provides - a solution to the intense research efforts in trying to engineer, probe and unravel many-body physics and the superconducting coupling mechanism in layered solids. The materials under investigation are based on the families of graphene, - dichalcogenides and iron based superconductors. Chemical functionalization using dopants and strain allows for an unprecedented control over their physical properties. The proposed material systems provide a new arena to explore diverse condensed - matter phenomena such as electron correlation, electron-phonon coupling and superconductivity. The groundbreaking aspects of this proposal are as follows: (1) development of a unique setup where electrical transport, angle-resolved photoemission - (ARPES) and optical spectroscopy is measured in-situ on the same sample, (2) large-area deterministic layer-by-layer growth by chemical vapour deposition (CVD) and molecular beam epitaxy, (3) the effects of mechanical strain and hence large - pseudomagnetic fields on the electronic band structure will be investigated using ARPES, (4) the effects of alkali metal doping on the superconducting transition temperature and the spectral function will be investigated using transport, ARPES and - optical spectroscopies shining light onto the superconducting pairing mechanisms in different classes of materials. The proposal's feasibility is firmly grounded on the pioneering work of the PI’s group on superconducting coupling in functionalized - graphene and the in-situ ARPES measurements of a CVD grown graphene/BN heterostructure. - - 2020-05-31, ongoing project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - SUPER-2D - - - ERC-2014-CoG - - - 648589 - - - - - NATIONAL UNIVERSITY OF IRELAND GALWAY - NATIONAL UNIVERSITY OF IRELAND GALWAY - - - EUR 1 499 431 - - - Clarifying Optimal Sodium Intake Project - - - EUR 1 499 431 - - - Ireland - Ireland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Hypertension is a leading risk factor for cardiovascular disease (CVD) globally, accounting for 25-35% of the population-attributable fraction. Sodium (salt) intake is a key determinant of blood pressure, and reducing sodium - intake has emerged as an important target for population-based interventions to prevent CVD. However, there is considerable uncertainty about the optimal level of sodium (salt) intake that is associated with lowest CVD risk, and whether optimal - levels differ for different populations and individuals. In this proposal, we will answer key fundamental research questions about the association of sodium intake with blood pressure and CVD risk. Our research challenges current guideline - recommendations of low-sodium intake for all populations. Specifically, we will: a) determine whether sustained (long-term) low sodium intake is associated with beneficial (or adverse) effects on established and novel CV biomarkers; b) explore - whether inter-daily ‘pattern’ of sodium intake is an important determinant of 24-hour blood pressure pattern; c) determine whether the association between sodium intake and CVD varies by ethnicity, sex, age, other dietary factors (e.g. potassium - intake), or other factors in 2 large international epidemiologic studies (PURE and INTERSTROKE; n>125,000 individuals); d) quantify the population-attributable fraction of excess sodium intake on global burden of CVD (stroke, myocardial - infarction, heart failure and CV death), and model the potential impact of various population-based approaches to reducing sodium intake; e) determine whether sodium intake is associated with other vascular-related clinical conditions, namely - including atrial fibrillation, cognitive impairment and falls (providing novel information); f) determine whether genetic variants associated with ‘salt sensitivity’ and hypertension are association with blood pressure and stroke, and whether these - associations are modified by sodium intake. - - 2020-04-30, ongoing project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Ireland - - - COSIP - - - ERC-2014-STG - - - 640580 - - - - - UNIVERSITETET I OSLO - UNIVERSITETET I OSLO - - - EUR 1 443 472 - - - Resonant Nuclear Gamma Decay and the Heavy-Element Nucleosynthesis - - - EUR 1 443 472 - - - Norway - Norway - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - THE GRAND CHALLENGE: The “Holy Grail” of nuclear astrophysics is to understand the astrophysical processes responsible for the formation of the elements. A particularly challenging part is the description of the heavy-element - nucleosynthesis. The only way to build the majority of these heavy nuclides is via neutron-capture processes. Unaccounted-for nuclear structure effects may drastically change these rates. - - - 2020-02-29, ongoing project - - - 2015-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Norway - - - gRESONANT - - - ERC-2014-STG - - - 637686 - - - - - ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOMATERIALES- CIC biomaGUNE - GLYCODIAG - UNIVERSITA DEGLI STUDI DI MILANO - UNIVERSITE GRENOBLE ALPES - UNIVERSITE JOSEPH FOURIER GRENOBLE 1 - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - STICHTING VU - DEUTSCHES KREBSFORSCHUNGSZENTRUM - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - UNIVERSITEIT LEIDEN - GLYCOUNIVERSE GMBH & CO KGAA - THE UNIVERSITY OF MANCHESTER - DC4U - MIDATECH PHARMA ESPANA SL - STIFTUNG TIERAERZTLICHE HOCHSCHULE HANNOVER - STICHTING VUMC - - - EUR 3 811 581 - - - Development of Selective Carbohydrate Immunomodulators Targeting C-type Lectin Receptors on Antigen Presenting Cells - - - EUR 3 811 581 - - - Spain - France - Italy - France - France - Spain - Netherlands - Germany - Germany - Netherlands - Germany - United Kingdom - Netherlands - Spain - Germany - Netherlands - - - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - IMMUNOSHAPE aims at training a new generation of scientists that will be capable of combining state of the art synthesis and screening technology to develop new lead structures for highly selective glycan based multivalent - immunotherapeutics for the treatment of cancer, autoimmune diseases and allergy. To this end, we have set up a training program in a unique academic-industrial environment that will educate young researchers in scientific and practical biomedical - glycoscience with the final aim to produce new talent and innovation in the field and improve their career perspectives in both academic and non-academic sectors. The unique combination of 10 academic groups with expertise in automated solid-phase - carbohydrate synthesis, microarray based highthroughput screening technology, tumour immunology, structural glycobiology, multivalent systems and medicinal chemistry along with 4 industrial partners active in nanomedicine, immunotherapy, medicinal - device development and the fabrication of scientific instrumentation will provide a multidisciplinary and multisectorial training to 15 ESRs in biomedical glycoscience and its industrial applications. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Spain - - - IMMUNOSHAPE - - - H2020-MSCA-ITN-2014 - - - 642870 - - - - - UNIVERSITAET ZU KOELN - UNIVERSITAET ZU KOELN - - - EUR 1 500 000 - - - Mediation of stem cell identity and aging by proteostasis - - - EUR 1 500 000 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - By 2050, the global population over the age of 80 will triple. Thus, research for improving the quality of life at older age can be of enormous benefit for our ever-aging society. To address this challenge we propose an - innovative approach based on a combination of stem cell research with genetic experiments in C. elegans. Mechanisms that promote protein homeostasis (proteostasis) slow down aging and decrease the incidence of age-related diseases. Since human - embryonic stem cells (hESCs) replicate continuously in the absence of senescence, we hypothesize that they can provide a novel paradigm to study proteostasis and its demise in aging. We have found that hESCs exhibit increased proteasome activity. - Moreover, we have uncovered that the proteasome subunit RPN-6 is required for this activity and sufficient to extend healtshpan in C. elegans. However, the mechanisms by which the proteasome regulates hESC function remain unknown. Our first aim is to - define how the proteasome regulates not only hESC identity but also aging and the onset of age-related diseases. Moreover, one of the next challenges is to define how other proteostasis pathways impinge upon hESC function. We hypothesize that, in - addition to the proteasome, hESCs differentially regulate other subcellular stress response pathways designed to protect them from disequilibrium in the folding and degradation of their proteome. We will perform a comprehensive study of proteostasis - of hESCs and mimic this network in somatic cells to alleviate age-related diseases. Finally, we will determine whether loss of proteostasis promotes somatic stem cell (SC) exhaustion, which is one of the most obvious characteristics of the aging - process and contributes to tissue degeneration. By using mouse models we will examine whether sustained proteostasis delays neural SC exhaustion. Our research will have an impact in several fields such as stem cell research, neurogenesis, - proteostasis, aging and age-related diseases. - - 2021-06-30, ongoing project - - - 2016-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - StemProteostasis - - - ERC-2015-STG - - - 677427 - - - - - UNIVERSITETET I OSLO - UNIVERSITETET I OSLO - - - EUR 2 000 000 - - - Controlling Cardiomyocyte Dyadic Structure - - - EUR 2 000 000 - - - Norway - Norway - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Contraction and relaxation of cardiac myocytes, and thus the whole heart, are critically dependent on dyads. These functional junctions between t-tubules, which are invaginations of the surface membrane, and the sarcoplasmic - reticulum allow efficient control of calcium release into the cytosol, and also its removal. Dyads are formed gradually during development and break down during disease. However, the precise nature of dyadic structure is unclear, even in healthy - adult cardiac myocytes, as are the triggers and consequences of altering dyadic integrity. In this proposal, my group will investigate the precise 3-dimensional arrangement of dyads and their proteins during development, adulthood, and heart failure - by employing CLEM imaging (PALM and EM tomography). This will be accomplished by developing transgenic mice with fluorescent labels on four dyadic proteins (L-type calcium channel, ryanodine receptor, sodium-calcium exchanger, SERCA), and by imaging - tissue from explanted normal and failing human hearts. The signals responsible for controlling dyadic formation, maintenance, and disruption will be determined by performing high-throughput sequencing to identify novel genes involved with these - processes in several established model systems. Particular focus will be given to investigating left ventricular wall stress and stretch-dependent gene regulation as controllers of dyadic integrity. Candidate genes will be manipulated in cell models - and transgenic animals to promote dyadic formation and maintenance, and reverse dyadic disruption in heart failure. The consequences of dyadic structure for function will be tested experimentally and with mathematical modeling to examine effects on - cardiac myocyte calcium homeostasis and whole-heart function. The results of this project are anticipated to yield unprecedented insight into dyadic structure, regulation, and function, and to identify novel therapeutic targets for heart disease - patients. - - 2020-06-30, ongoing project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Norway - - - CARDYADS - - - ERC-2014-CoG - - - 647714 - - - - - NATIONAL UNIVERSITY OF IRELAND GALWAY - NATIONAL UNIVERSITY OF IRELAND GALWAY - - - EUR 1 499 329 - - - Frontier Research on the Dielectric Properties of Biological Tissue - - - EUR 1 499 329 - - - Ireland - Ireland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The dielectric properties of biological tissues are of fundamental importance to the understanding of the interaction of electromagnetic fields with the human body. These properties are used to determine the safety of - electronic devices, and in the design, development and refinement of electromagnetic medical imaging and therapeutic devices. Many historical studies have aimed to establish the dielectric properties of a broad range of tissues. A growing number of - recent studies have sought to more accurately estimate these dielectric properties by standardising measurement procedures, and in some cases, measuring the dielectric properties in-vivo. However, these studies have often produced results in direct - conflict with historical studies, casting doubt on the accuracy of the currently utilised dielectric properties. At best, this uncertainty could significantly delay the development of electromagnetic imaging or therapeutic medical devices. At worst, - the health dangers of electromagnetic radiation could be under-estimated. The applicant will embark upon frontier research to develop improved methods and standards for the measurement of the dielectric properties of biological tissue. The research - programme will accelerate the design and development of electromagnetic imaging and therapeutic devices, at a time when the technology is gaining significant momentum. The primary objective of the research is to develop a deep understanding of the - fundamental factors which contribute to errors in dielectric property measurement. These factors will include in-vivo/ex-vivo measurements and dielectric measurement method used, amongst many others. Secondly, a new open-access repository of - dielectric measurements will be created based on a greatly enhanced understanding of the mechanisms underlying dielectric property measurement. Finally, new electromagnetic-based imaging and therapeutic medical devices will be investigated, based on - the solid foundation of dielectric data. - - 2020-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Ireland - - - BIOELECPRO - - - ERC-2014-STG - - - 637780 - - - - - UNIVERSITETET I OSLO - UNIVERSITETET I OSLO - - - EUR 1 571 553,75 - - - The Economics and Politics of Conservation - - - EUR 1 571 553,75 - - - Norway - Norway - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The UN’s approach to climate policy is to focus on national emission caps for greenhouse gases. Most of the economic theory on environmental agreements is also studying such a demand-side approach, even though it is well known - that such an approach has several flaws, including carbon leakage and the incentive to free ride. Recent theory has suggested that a better approach may be to focus on the supply-side of the equation, rather than the demand-side. While this recent - theory is promising, it is only indicative and has several shortcomings that must be analysed. The goal of this project is to investigate in depth how to best use conservation as an environmental policy tool. The project aims at integrating the - theory of emissions and pollution with a model of extraction and thus the supply of exhaustible resources in a coherent and dynamic game-theoretic framework. I will apply this framework to analyse negotiations, agreements, and contracts on extraction - levels, and how such policies can interact, complement or substitute for agreements focusing on consumption/emissions. It will also be important to develop and apply the tools of political economics to investigate which (second-best) agreement one - may expect to be feasible as equilibria of the game. For highly asymmetric settings, where the possessors of the resource are few (such as for tropical forests), side transfers are necessary and contract theory will be the natural analytical tool - when searching for the best agreement. However, also standard contract theory needs to be developed further once one recognizes that the “agent” in the principal-agent relationship is an organization or a government, rather than an individual. - - 2021-07-31, ongoing project - - - 2016-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Norway - - - CONSERVATION - - - ERC-2015-CoG - - - 683031 - - - - - UNIVERSITETET I OSLO - UNIVERSITETET I OSLO - - - EUR 1 350 000 - - - The role of 5HT3a inhibitory interneurons in sensory processing - - - EUR 1 350 000 - - - Norway - Norway - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - How do cortical circuits process sensory stimuli that leads to perception? Sensory input is encoded by complex interactions between principal excitatory neurons and a diverse population of inhibitory cells. Distinct inhibitory - neurons control different subcellular domains of target principal neurons, suggesting specific roles of different cells during sensory processing. However, the individual contribution of these inhibitory subtypes to sensory processing remains poorly - understood. This is mainly due to the technical challenges of recording the activity of identified cell types in-vivo, in response to quantified sensory stimuli. Therefore, I propose a novel approach based on four pillars: 1) An optically accessible - circuit in the superficial layers of the cortex, comprised of inhibitory cells expressing the serotonin receptor 5HT3a, and the distal dendrites of pyramidal neurons. 2) A novel combination of electrophysiology and 3D two-photon imaging to - simultaneously record the activity of morphologically identified 5HT3a cells and their dendritic targets. 3) A head-fixed perceptual decision task, whereby mice use their whiskers to determine the location of an object, allowing an accurate - description of the sensory stimulus. 4) The integration of experimental data and computer models to gain mechanistic insights into circuit functions. The 5HT3a cells and the distal dendrites of pyramidal neurons receive ‘top-down’ contextual - information from other cortical areas that is essential for constructing meaningful perceptions of sensory stimuli. Thus I hypothesize that 5HT3a cells influence sensory perceptions by controlling the excitability of the pyramidal cell distal - dendrites that integrate top-down and sensory input. Thus, I will not only reveal novel functions of inhibitory neurons, I will also shed light on how top-down and sensory input is integrated, and I will provide novel methods to test the functions of - other cell types in normal mice and disease models. - - 2020-05-31, ongoing project - - - 2015-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Norway - - - SurfaceInhibition - - - ERC-2014-STG - - - 639272 - - - - - THE UNIVERSITY OF SUSSEX - THE UNIVERSITY OF SUSSEX - - - EUR 1 500 000 - - - Zebrafish vision in its natural context: from natural scenes through retinal and central processing to behaviour. - - - EUR 1 500 000 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - All visual systems are specialised to best serve an animal’s sensory niche, yet how such specialisations are achieved through phylogenetic and developmental adaptations of the ‘common vertebrate visual system blueprint’ are - poorly understood. I will study these adaptations in the visual system of zebrafish. I will use two-photon functional imaging and computational modelling to investigate how the visual system of zebrafish samples and processes behaviourally meaningful - stimuli in the natural world. I will then use optogenetic manipulations while zebrafish navigate a virtual reality environment to directly probe the role of visual circuits in driving behaviour. Specifically, I will pursue four Aims: - - 2021-05-31, ongoing project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - NeuroVisEco - - - ERC-2015-STG - - - 677687 - - - - - ALFRED-WEGENER-INSTITUT HELMHOLTZ-ZENTRUM FUR POLAR- UND MEERESFORSCHUNG - - - EUR 171 460,80 - - - ARCGATE: maximizing the potential of Arctic Ocean Gateway array - - - EUR 171 460,80 - - - Germany - - - Research Organisations - - Predictions that the Arctic Ocean might be ice-free by the middle of the 21st century are of major social, economic, political and scientific interest. Making sensible decisions on European Arctic economic development requires - that scientific knowledge and data are more accessible and usable by both academics and non-academics alike. ARCGATE aims to obtain innovative physical and biogeochemical budgets for the Arctic Ocean based on the Arctic gateway observations. - Integrating Arctic gateway observations the applicant has recently developed an innovative method to obtain quasi-synoptic and time varying comprehensive budget estimates using a box inverse model. The main objective of ARCGATE is to extend the - inverse box model methodology to calculate multi-year Arctic heat and fresh water (FW) budget variations during 2004-2010, including import of heat, export of FW and storage of both. Over 20 million euro has already been spent on Arctic observations - during this period. The host institute of this proposal holds about half of historical Arctic gateway observations. The obtained budget estimates will be disseminated and exploited through an open data policy. Furthermore, ARCGATE aims to push - disciplinary and sectional boundaries. By applying the same pan-Arctic approach, the total alkalinity budget for summer 2005 will be calculated. A sound estimate of the total alkalinity budget will significantly advance understanding of the entire - carbonate system of the Arctic Ocean. Mobility from UK to Germany is key to the success of ARCGATE enabling synthesis of the pan-Arctic inverse box-model developed in UK over the last six years with state-of-the-art estimates of Arctic Ocean heat, FW - storage changes in time, and a new interpretation of total alkalinity all developed at the host institute for this project. Close links to the commercial Arctic shipping sector will be developed by disseminating the results of ARCGATE at - international shipping conferences. - - 2017-06-30, closed project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - ARCGATE - - - H2020-MSCA-IF-2014 - - - 652757 - - - - - INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE - INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE - INSTITUT MINES-TELECOM - - - EUR 1 492 252,50 - - - Signal processing and Learning Applied to Brain data - - - EUR 1 492 252,50 - - - France - France - France - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - - Understanding how the brain works in healthy and pathological conditions is considered as one of the challenges for the 21st century. After the first electroencephalography (EEG) measurements in 1929, the 90’s was the birth of - modern functional brain imaging with the first functional MRI and full head magnetoencephalography (MEG) system. In the last twenty years, imaging has revolutionized clinical and cognitive neuroscience. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - SLAB - - - ERC-2015-STG - - - 676943 - - - - - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - UNIVERSITETET I OSLO - - - EUR 1 413 750 - - - How nature affects cooperation in common pool resource systems - - - EUR 1 413 750 - - - Germany - Germany - Norway - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The constraints and dynamics set by nature have a deep and significant impact on economic fundamentals and the ability to successfully manage renewable resources. This can be taken into account to formulate effective policies. - However, the causal pathway from the natural to the social environment and its feedback for sustainable resource use is often overlooked, not the least because preferences and incentives are traditionally viewed as being stable and fixed. Yet, it is - high time to take this new perspective: Social-ecological systems around the globe are under mounting stress and common pool resources are vital, in particular in developing countries. This project aims to establish how nature shapes preferences and - incentives of economic agents and how this in turn affects common-pool resource management. To this end, I investigate three mechanisms: (A) how tipping points and thresholds in the natural system may encourage cooperation; (B) how the volatility of - resource abundance influences risk preferences and how this in turn affects community-based management; and (C) how leadership, which is closely linked to risk preferences, interacts with the natural environment to foster cooperation that overcomes - common-pool dilemmas. NATCOOP's bold agenda pushes the frontier of economics and sustainability science. Not only the investigation of the feedbacks between nature and cooperation from a new angle, also the scale and scope of the project -- combining - cases from different socio-economic and ecological setting at three continents with theoretical and statistical work -- will generate new knowledge and be highly rewarding. Though challenging, I am confident that my background in economics and - ecology puts me in an ideal position to achieve this important task. My ultimate goal is to identify circumstances in which natural preconditions and the social setting may go hand in hand to promote the sustainable use of renewable resources. - - 2021-07-31, ongoing project - - - 2016-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - NATCOOP - - - ERC-2015-STG - - - 678049 - - - - - UNIVERSITETET I OSLO - UNIVERSITETET I OSLO - - - EUR 1 995 963,75 - - - ALMA – The key to the Sun’s coronal heating problem. - - - EUR 1 995 963,75 - - - Norway - Norway - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - How are the outer layers of the Sun heated to temperatures in excess of a million kelvin? A large number of heating mechanisms have been proposed to explain this so-called coronal heating problem, one of the fundamental - questions in contemporary solar physics. It is clear that the required energy is transported from the solar interior through the chromosphere into the outer layers but it remains open by which physical mechanisms and how the provided energy is - eventually dissipated. The key to solving the chromospheric/coronal heating problem lies in accurate observations at high spatial, temporal and spectral resolution, facilitating the identification of the mechanisms responsible for the transport and - dissipation of energy. This has so far been impeded by the small number of accessible diagnostics and the challenges with their interpretation. The interferometric Atacama Large Millimeter/submillimeter Array (ALMA) now offers impressive - capabilities. Due to the properties of the solar radiation at millimeter wavelengths, ALMA serves as a linear thermometer, mapping narrow layers at different heights. It can measure the thermal structure and dynamics of the solar chromosphere and - thus sources and sinks of atmospheric heating. Radio recombination and molecular lines (e.g., CO) potentially provide complementary kinetic and thermal diagnostics, while the polarisation of the continuum intensity and the Zeeman effect can be - exploited for valuable chromospheric magnetic field measurements. - - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Norway - - - SolarALMA - - - ERC-2015-CoG - - - 682462 - - - - - UNIVERSITAET ZU KOELN - UNIVERSITAET ZU KOELN - - - EUR 1 676 423,75 - - - Many-Body Physics with Driven Open Quantum Systems of Atoms, Light and Solids - - - EUR 1 676 423,75 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Understanding the quantum many-particle problem is one of the grand challenges of modern physics. While tremendous progresses have been made over the past decades in thermodynamic equilibrium, nonequilibrium many-body quantum - physics is still in its infancy. Strong motivation for addressing this challenge comes from recent experimental developments in diverse areas, ranging from cold atomic gases over light-driven semiconductors to microcavity arrays. This moves systems - into the focus, which are located on the interface of quantum optics, many-body physics and statistical mechanics. They share in common that coherent and driven-dissipative quantum dynamics occur on an equal footing, creating scenarios without - immediate counterpart in traditional condensed matter systems. This project has the goal of pushing forward the understanding of such driven open quantum systems. To this end, we follow a combined approach structured around three key challenges. (i) - We aim to identify novel macroscopic phenomena, which manifestly witness microscopic non-equilibrium conditions. This concerns non-thermal stationary states, where we will shape an understanding of non-equilibrium phase diagrams and the associated - phase transitions, in particular constructing a notion of driven quantum criticality. But it also encompasses the identification of new universal regimes in open system time evolution. Finally, we will extend the concept of topological order to a - broader non-equilibrium context, motivated by quantum information applications. (ii) We will create new theoretical tools, in particular advancing a flexible Keldysh dynamical quantum field theory for driven open quantum systems. (iii) We will - address a broad spectrum of cutting edge experimental platforms in view of exploring our theoretical scenarios, and to foster mutual cross-fertilization. With an emphasis on cold atomic gases, this program also comprises exciton-polariton condensates - and coupled circuit QED architectures. - - 2021-01-31, ongoing project | - - - 2016-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - DOQS - - - ERC-2014-CoG - - - 647434 - - - - - UNIVERSITETET I OSLO - UNIVERSITETET I OSLO - - - EUR 2 900 000 - - - Disequilibirum metamorphism of stressed lithosphere - - - EUR 2 900 000 - - - Norway - Norway - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Most changes in mineralogy, density, and rheology of the Earth’s lithosphere take place by metamorphism, whereby rocks evolve through interactions between minerals and fluids. These changes are coupled with a large range of - geodynamic processes and they have first order effects on the global geochemical cycles of a large number of elements. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Norway - - - DIME - - - ERC-2014-ADG - - - 669972 - - - - - THE UNIVERSITY OF SUSSEX - THE UNIVERSITY OF SUSSEX - ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE - KOBENHAVNS UNIVERSITET - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 2 442 399,99 - - - Trust, Global Traders, and Commodities in a Chinese International City - - - EUR 2 442 399,99 - - - United Kingdom - United Kingdom - United Kingdom - Denmark - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Trust, Global Traders, and Commodities in a Chinese International City - - 2020-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - TRODITIES - - - ERC-2014-ADG - - - 669132 - - - - - UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA - UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA - - - EUR 1 672 103 - - - Harmonic Analysis and Differential Equations: New Challenges - - - EUR 1 672 103 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project sets forth cutting-edge challenges in the field of Mathematical Physics that will be solved within a common framework by making novel use of classical tools of Harmonic Analysis such as Oscillatory Integrals and - Trigonometric Sums, the Cauchy operator, and the so-called Carleman estimates. Three aspects will be covered: - - 2020-11-30, ongoing project - - - 2015-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Spain - - - HADE - - - ERC-2014-ADG - - - 669689 - - - - - NATIONAL UNIVERSITY OF IRELAND GALWAY - UNIVERSIDADE DO MINHO - THE ROYAL VETERINARY COLLEGE - UNIVERSITEIT MAASTRICHT - SOFRADIM PRODUCTION SASU - TECHNOLOGIKO EKPEDEFTIKO IDRYMA IPIROU - STEMCELL TECHNOLOGIES SARL - PROXY BIOMEDICAL LIMITED - STEMCELL TECHNOLOGIES UK LTD - - - EUR 3 876 965,64 - - - Engineering in vitro microenvironments for translation of cell-based therapies for tendon repair - - - EUR 3 876 965,65 - - - Ireland - Portugal - United Kingdom - Netherlands - France - Greece - France - Ireland - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Tendon Therapy Train is a research, training and innovation programme for human and equine tendon repair and regeneration that will exploit recent advancements in tissue engineering by self-assembly (TESA) technologies which - have led to the clinical translation and commercialisation of advanced therapy medicinal products (ATMPs). Although TESA therapies have the potential to revolutionise healthcare for numerous clinical targets, a lack of researchers with the necessary - interdisciplinary skillset to advance the field is limiting clinical translation. Tendon therapy train, a network of 8 beneficiaries and 8 partners (7 universities, 7 companies and 2 hospitals) from six countries across Europe, will train a cohort of - 15 researchers to doctoral level in the interdisciplinary area of ATMPs. The innovative credentials of the research and training programme involve engineering suitable ex vivo culture environments that, by mimicking the native tendon tissue milieu - (human and equine), will maintain the tenogenic phenotype of tendon derived cells and differentiate non-tendon derived cells (stem cells and dermal fibroblasts) towards the tenogenic lineage, subsequently enabling development of three-dimensional - cell-assembled tissue equivalents, the clinical potential of which will be assessed in suitable preclinical models. The comprehensive Tendon Therapy Train programme will equip researchers with transferable inter- and multidisciplinary skills that - will further European-based knowledge, innovation, competitiveness and leadership in the field of TESA / ATMP and ultimately enable clinical translation and commercialisation of the developed technologies. - - 2020-01-31, ongoing project - - - 2016-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Ireland - - - Tendon Therapy Train - - - H2020-MSCA-ITN-2015 - - - 676338 - - - - - UNIVERSITAET ZU KOELN - UNIVERSITAET ZU KOELN - - - EUR 2 499 735 - - - The Making of the Earth – Reading the Geochemical Code from Meteorites and the Earth’s Oldest Rocks - - - EUR 2 499 735 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - It is still an open question how Earth became the rocky habitable planet as we know it today. This is because there is a significant time gap of several 100 million years between Earth’s oldest rock archives (ca. 4 billion - years old) and most extraterrestrial samples like meteorites that archive the birth of our solar system ca. 4.5 billion years ago. Within this time gap, three key processes that shaped our planet took place, i.e., Earth’s growth via asteroidal - collisions, formation of the metal core and a first solid crust, and the delivery of volatiles such as water. Because rock samples are lacking, these fundamental processes have to be traced indirectly, by using highly sophisticated geochemical tools - like isotope or trace element compositions of younger rocks or meteorites. - - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - INFANT EARTH - - - ERC-2014-ADG - - - 669666 - - - - - NATIONAL UNIVERSITY OF IRELAND GALWAY - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN - RANDOX TEORANTA - GOETEBORGS UNIVERSITET - Fundació Institut d'Investigació Biomèdica de Bellvitge - LUDWIG BOLTZMANN GESELLSCHAFT OSTERREICHISCHE VEREINIGUNG ZUR FORDERUNG DER WISSENSCHAFTLICHEN FORSCHUNG - ROYAL COLLEGE OF SURGEONS IN IRELAND - KATHOLIEKE UNIVERSITEIT LEUVEN - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - OPTIMATA LTD - UNIVERSITAET STUTTGART - - - EUR 3 628 756,80 - - - Endoplasmic Reticulum Stress in Health and Disease - - - EUR 3 628 756,80 - - - Ireland - France - Germany - Ireland - Sweden - Spain - Austria - Ireland - Belgium - United Kingdom - Israel - Germany - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - Endoplasmic reticulum (ER) stress is emerging as a common feature in the pathology of numerous diseases including cancer, neurodegenerative disorders, metabolic syndromes and inflammatory diseases. Thus ER stress represents a - potential therapeutic intervention point to be exploited to develop novel therapies, diagnostic tools and markers for these diseases. However, exploitation is hampered by the shortage of scientists with interdisciplinary training that can navigate - with ease between the academic, industrial and clinical sectors, and that have the scientific and complementary skills, together with an innovative outlook, to convert research findings into commercial and clinical applications. This proposal will - bring young researchers together with world-leading academics, clinicians and industry personnel, who are united in (1) their goal of forming a network of excellence aimed at understanding the ER stress response mechanistically and quantitatively and - (2) applying this understanding to identify and validate the most suitable intervention points in order to provide innovative knowledge-driven strategies for the treatment of ER stress-associated diseases. - - - 2019-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Ireland - - - TRAIN-ERS - - - H2020-MSCA-ITN-2015 - - - 675448 - - - - - NATIONAL UNIVERSITY OF IRELAND GALWAY - - - EUR 233 555,40 - - - Genome editing for spatiotemporal analysis of centriolar SATellite BIOgenesis and FUNction in cellular stress responses - - - EUR 233 555,40 - - - Ireland - - - Higher or Secondary Education Establishments - - The centrosome is the major microtubule-organizing centre of a cell. It also serves as the base for the primary cilium, an antenna-like structure that allows cells to respond to external stimuli. Around the centrosome lie a - number of electron dense cytoplasmic granules, termed centriolar satellites. These are involved in protein trafficking and are crucial for normal centrosome and cilium assembly and function. However, little is known about satellite composition, - biogenesis or regulation. Mutations in a number of genes encoding satellite proteins cause ciliopathies, demonstrating their importance in the etiology of disease. Emerging data also shows that satellites contribute to the cellular stress response. - The central scientific goal of this proposal is to systematically dissect, for the first time, the molecular mechanisms underpinning centriolar satellite biogenesis and function. Coupling genome-editing and cutting-edge imaging techniques we will - perform morphometric quantitative analysis of satellite proteins to delineate their specific role in the cellular response to stress. This project encompasses an Outgoing Phase during which the Fellow will be trained in advanced, high-content, - automated, and super-resolution microscopy, and computational analysis to study satellite biogenesis and function. Within this phase a secondment to the biotech sector will occur during which the Fellow will learn cutting-edge DNA manipulation - methods. The Return Phase allows the transfer of this knowledge to Europe whilst the Fellow receives training in the analysis of stress responses. Alongside this the Fellow will follow a program of courses to acquire a range of complementary skills, - including industry-related skills and teaching qualifications. Together, this will accomplish the overarching objective of developing the Fellow’s career to a position of professional maturity, thereby facilitating her long-term goal of establishing - her own independent research group in Europe. - - 2019-06-30, ongoing project - - - 2016-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Ireland - - - SATBIOFUN - - - H2020-MSCA-IF-2015 - - - 702601 - - - - - CENTRE D ESTUDIS DEMOGRAFICS - CENTRE D ESTUDIS DEMOGRAFICS - - - EUR 1 174 500 - - - Equalizing or disequalizing? Opposing socio-demographic determinants of the spatial distribution of welfare. - - - EUR 1 174 500 - - - Spain - Spain - - - Research Organisations - Research Organisations - - This project aims to investigate the extent to which current trends in family formation, living arrangements and gender-specific education levels are related to the spatial distribution of welfare and the emergence of jobless - households in contemporary societies. Inter alia, we aim to explore whether the welfare disequalizing, impoverishing and polarizing effects that are currently associated with recent patterns in assortative mating, lone parenthood and household - composition are offset by an unprecedented phenomenon that is sweeping the world during the last decades: the rapid process education expansion in tandem with a reversal of the gender gap in education. The extent to which these two opposing forces - occur and which of them is more influential in shaping the distribution of welfare between and within countries is among the main goals of this project. To this end, we will draw upon a variety of household surveys and the world largest sources of - census microdata: the Integrated Public Use Microdata Series (IPUMS) project and the Latin American and Caribbean Demographic Centre. Because of their unparalleled geographical coverage and detail, these sources of data constitute exceptional - instruments to study socio-demographic phenomena that have been vastly underutilized by the international research community. Triangulating our analysis at the micro, meso and macro levels, we will establish formal linkages between welfare - distributions and its socio-demographic correlates to unveil insightful relationships that have been unsatisfactorily explored so far because of the lack of appropriately harmonized, sufficiently detailed and georeferenced datasets. We will strongly - emphasize the spatial distribution of variables to unravel local patterns that might take place at highly disaggregated levels, therefore not being discernible to traditional (not as finely-grained) approaches. - - 2020-04-30, ongoing project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Spain - - - EQUALIZE - - - ERC-2014-STG - - - 637768 - - - - - THE UNIVERSITY OF SUSSEX - THE UNIVERSITY OF SUSSEX - USTAV MOLEKULARNI GENETIKY AKADEMIE VED CESKE REPUBLIKY VEREJNA VYZKUMNA INSTITUCE - - - EUR 2 447 409 - - - Defective DNA Damage Responses in Dominant Neurodegenerative Diseases - - - EUR 2 447 409 - - - United Kingdom - United Kingdom - Czech Republic - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - DNA single-strand breaks (SSBs) are the most frequent DNA lesions arising in cells and are a major threat to cell survival and genome integrity, as indicated by the elevated genetic deletion, embryonic lethality, or - neurological disease observed if single-strand break repair (SSBR) is attenuated. In particular, SSBR defects are associated with hereditary neurodegeneration in humans, as illustrated by the genetic diseases ataxia oculomotor apraxia-1 (AOA1), - spinocerebellar ataxia with axonal neuropathy-1 (SCAN1), and microcephaly with early onset seizures (MCSZ). However, two major questions remain: what are the mechanisms by which SSBs trigger neurodegeneration, and to what extent do SSBs contribute to - other genetic and/or sporadic neurodegenerative disease? Based on exciting new data we now propose that the impact of SSBs on neurodegeneration extends beyond rare SSBR-defective diseases to include more common motor neurone diseases (amyotrophic - lateral sclerosis) and the genetically dominant spinocerebellar ataxias (SCAs). Ultimately, we suggest that SSBs might also be an etiological factor in normal human ageing. Finally, again based on new data, we propose that SSBs induce - neurodegeneration by triggering over-activation of the SSB sensor protein, PARP1; thereby identifying inhibitors of this protein (currently licensed for cancer treatment) as a possible therapy for neurodegeneration. We will now address these - hypotheses using a range of cutting edge molecular/cellular techniques. In particular we will (a), systematically examine all relevant amyotrophic lateral sclerosis/motor neurone disease (ALS/MND) and spinocerebellar ataxia (SCA) proteins for - involvement in the DNA damage response, (b) Identify the mechanism/s by which ALS and SCA proteins engage in the DNA damage response, (c) Identify the role of ALS and SCA proteins in the DNA damage response, and (d) Explore PARP1 as a possible - therapeutic target for treatment of neurodegenerative disease. - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - SIDSCA - - - ERC-2015-AdG - - - 694996 - - - - - NATIONAL UNIVERSITY OF IRELAND GALWAY - - - EUR 2 194 800 - - - Career Development and Mobility Fellowships in Medical Device Research and Development: A CÚRAM Industry-Academia Training Initiative. - - - EUR 4 389 600 - - - Ireland - - - Higher or Secondary Education Establishments - - MedTrain is a new Industry-Academia Training, Career Development, and Mobility Fellowship Programme in Medical Device Research and Development at CÚRAM. CÚRAM, the national Centre for Research in Medical Devices, is a - distributed research centre, headquartered in the National University of Ireland, Galway (NUIG), and composed of multiple academic partners from around Ireland (NUIG, University College Dublin (UCD), University College Cork (UCC), Royal College of - Surgeons in Ireland (RCSI), Molecular Medicine Ireland) and 35+ industry partners. MedTrain will offer 31 prestigious two-year postdoctoral fellowships for incoming mobility to eligible Experienced Researchers in the area of Medical Device Research - and Development across two calls. Experienced researchers, by definition under Marie Skłodowska-Curie Actions (MSCA), are those in possession of a doctoral degree (or at least four years full-time equivalent research experience) at the time of the - recruitment by the host organisation. Fellowships must comply with the MSCA mobility rule. Career breaks will be taken into account. Fellowships are open to candidates of any nationality who shall not have resided or carried out their main activity - (work, studies, etc.) in Ireland for more than 12 months in the three years immediately prior to the time of recruitment by the host organisation. Compulsory national service and/or short stays such as holidays are not taken into account. MedTrain is - based on individual-driven mobility, meaning that fellows will have the freedom to choose their research area (provided it falls within the remit of CÚRAM), their supervisor and their secondment organisation. Fellows will be hosted in a CÚRAM - academic host organisation (NUIG, UCC, UCD, RCSI) and will second to a suitable research performing organisation in the non-academic sector, located in any country in the world appropriate to meet the needs of the fellows’ research, training and - career development requirements. - - 2020-10-31, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2015-FP - Marie Skłodowska-Curie Co-funding of regional, national and international programmes (COFUND-FP) - - - MSCA-COFUND-FP - Fellowship programmes - - - Ireland - - - MedTrain - - - H2020-MSCA-COFUND-2015 - - - 713690 - - - - - OSLO UNIVERSITETSSYKEHUS HF - ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON - UNIVERSITAT POLITECNICA DE VALENCIA - KNIGHT SCIENTIFIC LIMITED - UNIVERSITETET I OSLO - - - EUR 3 031 375 - - - A paradigm shift in cancer therapy – using mitochondria-powered chemiluminescence to non-invasively treat inaccessible tumours - - - EUR 3 031 375 - - - Norway - Greece - Spain - United Kingdom - Norway - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - Brain cancers such as glioblastoma multiforme (GBM) are practically incurable due to their location, invasiveness and highly aggressive nature. The use of light-based treatments of GBM by activating tumor-localized - photosensitizers, such as in photodynamic therapy (PDT) has been clinically evaluated, but with limited success. This is mainly due to the limited penetration of light into tissue and the efficient spread of tumor cells typically up to at least 2 cm - from the resection margin. Moreover, the existing photon based treatments (photodynamic therapy) are highly invasive and usually require open-cranium surgery, due to the need for external light sources. In the Lumiblast project the photons are - produced inside the tumor cells in the form of chemiluminescence avoiding the major limitation of using external light to treat solid, deep-sited and inaccessible tumors. The principle utilized in Lumiblast may also be relevant for cancers of other - origins. Due to its nature Lumiblast is expected to act on individual cells, rather than the collective lesion; it could thus completely eliminate the hitherto incurable GBM. Each GBM cell is expected to become a small lamp providing the light - required for the photosensitive agents to become activated, killing the tumour cells from the inside. Lumiblast requires a concerted interdisciplinary action. The project coordinator (Berg’s group, Oslo University Hospital, OUS) is world renowned in - PDT and photomedicine, while the team from the University of Athens (Georgios Vougioukalakis’ group, UoA) is up and coming with high expertise in synthetic chemistry. The Polytechnic University of Valencia (Miguel Miranda’s group, UPV) team is headed - by a world leader in Photochemistry, the University of Oslo partner (Hanne H. Tønnensen’s group, UiO) is specialized in pharmaceutical formulation, and Knight Scientific Ltd (KSL, CEO Jan Knight) is an SME with an impressive track record in - ROS-activated luminescence. This 4.5-year project will establish the Lumiblast breakthrough technology by providing proof-of-concept in extracellular systems, GBM cell cultures and animal models, with the vision to advance Lumiblast to the clinic 5-6 - years after the end of the proposed project. - - 2021-03-31, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-1-2014 - FET-Open research projects - - - RIA - Research and Innovation action - - - Norway - - - Lumiblast - - - H2020-FETOPEN-2014-2015-RIA - - - 712921 - - - - - TECHNISCHE UNIVERSITAET DRESDEN - NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU - VYSOKA SKOLA BANSKA - TECHNICKA UNIVERZITA OSTRAVA - NATIONAL UNIVERSITY OF IRELAND GALWAY - INTEL CORPORATION SAS - TECHNISCHE UNIVERSITAET MUENCHEN - GNS MBH GESELLSCHAFT FUR NUMERISCHE SIMULATION MBH - - - EUR 3 534 198,75 - - - Runtime Exploitation of Application Dynamism for Energy-efficient eXascale computing - - - EUR 3 534 198,75 - - - Germany - Norway - Czech Republic - Ireland - France - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - High Performance Computing (HPC) has become a major instrument for many scientific and industrial fields to generate new insights and product developments. There is a continuous demand for growing compute power, leading to a - constant increase in system size and complexity. Efficiently utilizing the resources provided on Exascale systems will be a challenging task, potentially causing a large amount of underutilized resources and wasted energy. Parameters for adjusting - the system to application requirements exist both on the hardware and on the system software level but are mostly unused today. Moreover, accelerators and co-processors offer a significant performance improvement at the cost of increased overhead, - e.g., for data-transfers. - - 2018-08-31, ongoing project | - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.2."> - - - FETHPC-1-2014 - HPC Core Technologies, Programming Environments and Algorithms for Extreme Parallelism and Extreme Data Applications - - - RIA - Research and Innovation action - - - Germany - - - READEX - - - H2020-FETHPC-2014 - - - 671657 - - - - - ERDYN CONSULTANTS - ZENTRUM FUR SOZIALE INNOVATION GMBH - RISE RESEARCH INSTITUTES OF SWEDEN AB - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - AGENCE NATIONALE DE LA RECHERCHE - - - EUR 799 837,50 - - - Tools and Actions for Impact Assessment and Policy makers Information - - - EUR 873 442,50 - - - France - Austria - Sweden - Switzerland - France - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - TAIPI, Tools and Actions for Impact Assessment and Policy makers Information, is a CSA proposal to the “Policy environment for FET Flagships” topic of the call H2020-FETFLAG-2014. TAIPI addresses the scope of the this topic by - undertaking actions related to: (i) Assessing the impacts of FET Flagship initiatives, including through metrics and indicators; (ii) Collection of information need for policy making, e.g. through consultation actions and surveys. The general - objective of TAIPI is to support and strengthen the FET Flagship Initiative and the two selected Flagships. Specific objectives of TAIPI are: (i) To develop assessment methodologies along with the required toolkits which will be applied respectively - to HBP and Graphene Flagships, (ii) To carry out the impact assessment of both Flagships and the Flagship policy by applying the specifically developed methodology and tools, (iii) To collect and provide information for policy makers and funding - organizations participating to Flagships initiative, (iv) To transfer to the Flagships these developed toolkits, and to enable them to use these tools after the end of the CSA, thus ensuring the sustainability of the project activities. TAIPI is - composed of 5 work packages: WP1 Management, WP2 Development of methodology, WP3 Impact assessment, WP4 Support to policy makers, WP5 Dissemination. TAIPI will assess the impacts of HBP and Graphene, enhance the flow of information from the Flagships - towards policy makers, relevant stakeholders and wider public, improve the understanding of the impacts of the Flagships on science, technology, economy and society and contribute to create a stable and structured environment for the benefit of the - FET Flagships. The environment created by TAIPI will thus benefit to the Flagships, allowing them to concentrate on the fields where they bring the highest added value to their stakeholders while they rely on up-to-date tools, developed by TAIPI, to - monitor in real time their impacts. - - 2017-12-31, closed project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.3."> - - - FETFLAG-2-2014 - 2014: Policy environment for FET Flagships - - - CSA - Coordination and support action - - - France - - - TAIPI - - - H2020-FETFLAG-2014 - - - 650029 - - - - - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - UNIVERSITE CLERMONT AUVERGNE - UNIVERSITE BLAISE PASCAL CLERMONT-FERRAND II - THE UNIVERSITY OF SUSSEX - RIJKSUNIVERSITEIT GRONINGEN - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - KARLSRUHER INSTITUT FUER TECHNOLOGIE - - - EUR 2 892 500 - - - Mind and Time: Investigation of the Temporal Traits of Human-Machine Convergence - - - EUR 2 892 500 - - - Greece - France - France - United Kingdom - Netherlands - United Kingdom - Germany - - - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Contemporary research endeavours aim at equipping artificial systems with human-like cognitive skills, in an attempt to promote their intelligence beyond repetitive task accomplishment. However, despite the crucial role that - the sense of time has in human cognition, both in perception and action, the capacity of artificial agents to experience the flow of time remains largely unexplored. The inability of existing systems to perceive time constrains their potential - understanding of the inherent temporal characteristics of the dynamic world, which in turn acts as an obstacle to their symbiosis with humans. Time perception is without doubt, not an optional extra, but a necessity for the development of truly - autonomous, cognitive machines. - - 2018-06-30, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.2."> - - - FETPROACT-2-2014 - Knowing, doing, being: cognition beyond problem solving - - - RIA - Research and Innovation action - - - Greece - - - TIMESTORM - - - H2020-FETPROACT-2014 - - - 641100 - - - - - EBERHARD KARLS UNIVERSITAET TUEBINGEN - CARL VON OSSIETZKY UNIVERSITAET OLDENBURG - UNIVERSITETET I BERGEN - THE UNIVERSITY OF SUSSEX - KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW - TECHNISCHE UNIVERSITAET WIEN - UNIVERSITAET INNSBRUCK - CONSIGLIO NAZIONALE DELLE RICERCHE - MULTI CHANNEL SYSTEMS MCS GMBH - EKB TECHNOLOGIES LTD - INILABS GMBH - - - EUR 3 867 784,92 - - - In the eye of the observer: Visual processing at the heart of the retina - - - EUR 3 867 784,92 - - - Germany - Germany - Norway - United Kingdom - Netherlands - Austria - Austria - Italy - Germany - Israel - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - All visual information is broadcasted by an intra-retinal pathway formed by a group of neurons called bipolar cells. They collect photoreceptor signals in the outer retina and relay the signals to the inner retinal neurons. - This transfer of visual information is far from passive: Each of the at least 10 bipolar cell types transforms the photoreceptor signals in a unique and highly specific way. As a result, the bipolar cell output signals form the first “elementary - operations” from which the neural circuits of the inner retina compose a feature-oriented description of the visual world. Reflecting the partitioning of visual information into parallel channels, the retinal layer in which bipolar cell axon - terminals meet their synaptic partners, is highly organized: This so-called “inner plexiform layer” effectively serves as the retina’s “switch board”: The input is provided by the different bipolar cell “channels”, while the output is carried by an - even larger number of channels, represented by ganglion cells that form the optic nerve. Each of the ~20 ganglion cell types composes its feature-extracting circuits from a specific set of bipolar cell input it receives. Owing to its regular - structure and ease of experimental access, the retina is amongst the best understood self-standing neuronal networks in neuroscience. Indeed, recent advances hold the exciting promise that an in-depth understanding of the bipolar cells – an entire - class of neurons – and their role in the first critical steps of visual processing is within reach. Our proposal aims to train young researchers in world-leading research labs towards completing this goal. We will accomplish this by exposing the - students to a host of cutting-edge techniques and a broad spectrum of research approaches within the training network – from imaging at synaptic resolution, transgenetics and retina degeneration models to the application of retinal circuit principles - for signal processing in artificial vision chips. - - 2019-10-31, ongoing project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - switchBoard - - - H2020-MSCA-ITN-2015 - - - 674901 - - - - - EUROPEAN CENTRE FOR MEDIUM-RANGE WEATHER FORECASTS - METEO-FRANCE - INSTITUT ROYAL METEOROLOGIQUE DE BELGIQUE - DANMARKS METEOROLOGISKE INSTITUT - EIDGENOESSISCHES DEPARTEMENT DES INNERN - DEUTSCHER WETTERDIENST - LOUGHBOROUGH UNIVERSITY - NATIONAL UNIVERSITY OF IRELAND GALWAY - INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK - BULL SAS - NVIDIA SWITZERLAND AG - OPTALYSYS - - - EUR 3 977 952,50 - - - Energy-efficient SCalable Algorithms for weather Prediction at Exascale - - - EUR 3 977 952,50 - - - United Kingdom - France - Belgium - Denmark - Switzerland - Germany - United Kingdom - Ireland - Poland - France - Switzerland - United Kingdom - - - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - ESCAPE will develop world-class, extreme-scale computing capabilities for European operational numerical weather prediction (NWP) and future climate models. The biggest challenge for state-of-the-art NWP arises from the need - to simulate complex physical phenomena within tight production schedules. Existing extreme-scale application software of weather and climate services is ill-equipped to adapt to the rapidly evolving hardware. This is exacerbated by other drivers for - hardware - - - 2018-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.2."> - - - FETHPC-1-2014 - HPC Core Technologies, Programming Environments and Algorithms for Extreme Parallelism and Extreme Data Applications - - - RIA - Research and Innovation action - - - United Kingdom - - - ESCAPE - - - H2020-FETHPC-2014 - - - 671627 - - - - - NATIONAL UNIVERSITY OF IRELAND GALWAY - NATIONAL UNIVERSITY OF IRELAND GALWAY - - - EUR 891 386 - - - Voices Of Individuals: Collectively Exploring Self-determination - - - EUR 891 386 - - - Ireland - Ireland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The right to make one’s own decisions and to have these decisions respected by law is a basic human freedom which most adults take for granted. However, for many people with disabilities (especially people with intellectual, - psycho-social and other cognitive disabilities) this fundamental right has been denied – informally, in the private sphere, and formally, in the public sphere through States’ laws and policies. - - - 2018-11-30, ongoing project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Ireland - - - VOICES - - - ERC-2014-STG - - - 638768 - - - - - THE UNIVERSITY OF EDINBURGH - INTEL GMBH - INTEL DEUTSCHLAND GMBH - FUJITSU TECHNOLOGY SOLUTIONS GMBH - BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION - TECHNISCHE UNIVERSITAET DRESDEN - ALLINEA SOFTWARE LIMITED - EUROPEAN CENTRE FOR MEDIUM-RANGE WEATHER FORECASTS - ARCTUR RACUNALNISKI INZENIRING DOO - - - EUR 8 114 504 - - - Next Generation I/O for Exascale - - - EUR 8 114 504 - - - United Kingdom - Germany - Germany - Germany - Spain - Germany - United Kingdom - United Kingdom - Slovenia - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The overall objective of the Next Generation I/O Project (NEXTGenIO) is to design and prototype a new, scalable, high-performance, energy efficient computing platform designed to address the challenge of delivering scalable - I/O performance to applications at the Exascale. It will achieve this using highly innovative, non-volatile, dual in-line memory modules (NV-DIMMs). These hardware and systemware developments will be coupled to a co-design approach driven by the - needs of some of today’s most demanding HPC applications. By meeting this overall objective, NEXTGenIO will solve a key part of the Exascale challenge and enable HPC and Big Data applications to overcome the limitations of today’s HPC I/O subsystems. - - 2018-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.2."> - - - FETHPC-1-2014 - HPC Core Technologies, Programming Environments and Algorithms for Extreme Parallelism and Extreme Data Applications - - - RIA - Research and Innovation action - - - United Kingdom - - - NEXTGenIO - - - H2020-FETHPC-2014 - - - 671591 - - - - - UNIVERSITAET ZU KOELN - UNIVERSITAET ZU KOELN - UNIVERSITAET BREMEN - - - EUR 1 125 575 - - - Enhanced Qualitative and Multi-Method Research in Political Science - - - EUR 1 125 575 - - - Germany - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Over the last 20 years, qualitative methods in political science have developed rapidly on three dimen-sions. First, set theory was formulated as an alternative to what is called the quantitative worldview. Second, process - tracing for the analysis of mechanisms evolved as a complement to the estimation of marginal effects. Process tracing has also been tied to Bayesianism as opposed to frequentism. Third, process tracing became an element of multi-method research - (MMR), integrating it with frequentist statistics or Qualitative Comparative Analysis (QCA). - - - 2020-04-30, ongoing project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - ENHANCEDQMMR - - - ERC-2014-STG - - - 638425 - - - - - NATIONAL UNIVERSITY OF IRELAND GALWAY - NATIONAL UNIVERSITY OF IRELAND GALWAY - - - EUR 149 101 - - - Medically Licensed Mesenchymal Stem Cells for Acute Respiratory Distress Syndrome. - - - EUR 149 101 - - - Ireland - Ireland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Acute Respiratory Distress Syndrome (ARDS) is a devastating condition, which kills 40% of sufferers, resulting in hundreds of thousands of deaths worldwide annually. Despite decades of intensive research efforts, there are no - clinical therapeutic strategies available for this catastrophic condition. In our ERC Starter Grant, HA-NFkB-VILI, we have shown Mesenchymal Stem Cells (MSCs) to be beneficial in several relevant preclinical ARDS models. - - - 2015-12-31, closed project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2014 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Ireland - - - CCMI-ARDS - - - ERC-2014-PoC - - - 641392 - - - - - UNIVERSITETET I OSLO - UNIVERSITETET I OSLO - - - EUR 1 495 079 - - - Enacting the Good Economy: Biocapitalization and the little tools of valuation - - - EUR 1 495 079 - - - Norway - Norway - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - What shall we live off in the future? Where will our food come from, and what will form the basis for our economies? A so-called “blue revolution”, where fish become farmed rather than caught, is increasingly presented as an - answer to the above questions. This transformation of the economy exemplifies ongoing efforts to produce new forms of capital out of the ordering and reordering of life. These processes are intimately related to the expanding life sciences, the - bioeconomy and what is sometimes called new forms of biocapital. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Norway - - - LITTLE TOOLS - - - ERC-2014-STG - - - 637760 - - - - - THE UNIVERSITY OF SUSSEX - - - EUR 195 454,80 - - - Healing from Enclosure: A Political Agroecology of a Science-and-Society Potato Controversy in Belgium - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Against the background of the ongoing crisis of the world’s food systems, this research project investigates how agricultural knowledge shapes, and is shaped by, its broader cultural, economic, socio-technical and - socio-ecological context. A transdisciplinary approach –theoretically and empirically explorative, methodologically innovative, and action-oriented—to the production, transmission and application of agricultural knowledge in Belgium, and Europe more - broadly, offers a powerful way of thinking about the complex relationships that exist between food systems and agricultural knowledge. - - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - HealingFromEnclosure - - - H2020-MSCA-IF-2015 - - - 707807 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - FUNDACION PARA EL FOMENTO DE LA INVESTIGACION SANITARIA Y BIOMEDICA DE LA COMUNITAT VALENCIANA - - - EUR 1 671 875 - - - Integrating genomics, epidemiology and evolution to accelerate tuberculosis eradication - - - EUR 1 671 875 - - - Spain - Spain - Spain - - - Research Organisations - Research Organisations - Research Organisations - - When the scale of the tuberculosis (TB) epidemic was highlighted by its declaration as a "Global Emergency" by WHO in 1993, it was envisaged that the efficient use of existing tools would result in a progressive decline - towards eradication. This has not occurred. At the current pace of decline in TB incidence the Millennium objective to eradicate it by 2050 will not be met. Predictions of epidemiological models were inaccurate and current control programs and - technologies have shown their limitations to control the transmission of the disease. To overcome these limitations we need a technological, methodological and conceptual leap forward that can reveal the unknowns of TB epidemiology. I propose whole - genome sequencing (WGS) as the technology that can mediate this advance. While WGS has been applied mostly to retrospective datasets I propose to use it in prospective samples from a low-burden region at a population scale. Genome information will - fill the gap between epidemiology and evolution to have a direct impact on public health. This will allow to develop innovative methodologies to describe transmission at an unprecedented resolution and as a consequence to differentiate among risks - factors associated to the bacteria, the host, the environment and their interactions. Elucidation of these factors will lead to better models used to design new strategies and accelerate global TB eradication. In addition, I will show how the - real-time integration of data in public eHealth systems combined with in situ interventions will accelerate TB eradication. The strength of the project resides in its multidisciplinary approach to TB epidemiology that will provide answers to - yet-out-of-reach questions. It will lead to improving health status at the local level as well as to epidemiological and control programs at a global scale. In summary, the project will open new ways to foster the long sought outcome of the - tuberculosis community: TB eradication. - - 2020-06-30, ongoing project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Spain - - - TB-ACCELERATE - - - ERC-2014-STG - - - 638553 - - - - - UNIVERSITAET ZU KOELN - UNIVERSITAET ZU KOELN - - - EUR 1 965 250 - - - Reading Global. Constructions of World Literature and Latin America - - - EUR 1 965 250 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The debate on world literature is among the most significant cultural historical controversies of our time. This contribution to the debate aims to pursue two goals in particular: - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - RG - - - ERC-2014-CoG - - - 646714 - - - - - UNIVERSITETET I OSLO - UNIVERSITETET I OSLO - - - EUR 1 499 572 - - - Bivariational Approximations in Quantum Mechanics and Applications to Quantum Chemistry - - - EUR 1 499 572 - - - Norway - Norway - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The standard variational principles (VPs) are cornerstones of quantum mechanics, and one can hardly overestimate their usefulness as tools for generating approximations to the time-independent and time-dependent Schröodinger - equations. The aim of the proposal is to study and apply a generalization of these, the bivariational principles (BIVPs), which arise naturally when one does not assume a priori that the system Hamiltonian is Hermitian. This unconventional approach - may have transformative impact on development of ab initio methodology, both for electronic structure and dynamics. - - 2020-03-31, ongoing project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Norway - - - BIVAQUM - - - ERC-2014-STG - - - 639508 - - - - - ALFRED-WEGENER-INSTITUT HELMHOLTZ-ZENTRUM FUR POLAR- UND MEERESFORSCHUNG - - - EUR 171 460,80 - - - Up-scaling Arctic diversity analysis to link community organisation and ecosystem functioning - - - EUR 171 460,80 - - - Germany - - - Research Organisations - - Arctic oceans are undergoing major changes in many of its fundamental physical constituents, such as a shift from multi- to first-year ice, shorter ice-covered periods, increasing freshwater runoff, and warming and alteration - in the distribution of water masses. Such changes, often resulting from anthropogenic stressors, have profound impacts on the chemical and biological processes that are at the root of Arctic marine food webs, influencing their structure, function and - biodiversity. Yet, much research addressing these on-going changes is practically and financially limited to local scales or rather exploratory by nature, making it imperative to better characterise and understand the structural and functional - diversity of ecological systems that contribute to the marine Arctic across larger scales. We aim to offer more insight in the distributions and abundance of macrobenthic species in Arctic seascapes, e.g. bivalves, polychaetes, and crustaceans that - live in marine soft bottoms. Building on recent pan-Arctic community data from ~5000 locations, we address a fundamental challenge in Arctic ecological research by employing quantitative methods thus far not feasible. We will use multi-species - distribution models that allow determining interactions between species; link functions to environmental characteristics using 4th-corner models. Key is that such approaches link traits and environment without the necessity of including sample - locations, holding promise for an approach that translates ecosystem function directly to services; look for indirect interactions and feedbacks between polar benthic macrofauna and ecosystem functioning by employing structural equation models. This - enables full inference of spatial diversity patterns of Arctic benthic communities and link community organisation and ecosystem functioning, allowing us to understand the interplay between fine- and broad-scale patterns and processes structuring - rapidly changing polar benthic ecosystems. - - 2018-05-31, ongoing project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - ARCDIV - - - H2020-MSCA-IF-2015 - - - 700796 - - - - - UNIVERSITAET ZU KOELN - - - EUR 171 460,80 - - - Costs and optimality of gene expression levels in Escherichia coli - - - EUR 171 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - The precise expression of protein coding genes is of crucial importance to all organisms, since proteins are involved in virtually all vital processes. Some proteins need to be available at exactly the right amount to perform - cellular functions sustainably and thereby maximize fitness. Consequently, gene expression needs to be accurately controlled. For these reasons, it has been hypothesized that cells evolve towards a state in which expression levels are optimally tuned - to maximize fitness in the current environment. The cell’s growth and resource distribution is constrained by tradeoffs between the costs and benefits of a particular expression level. Recent investigations of the global effects of protein levels - provide insights into the mutual dependency between expression and growth. To test this central hypothesis in systems biology, we use Escherichia coli which is the best-characterized model organism for fundamental research on gene expression, as well - as for biotechnological applications. We aim to advance the understanding of the costs and benefits of expression by systematically investigating its ~4000 genes with gene deletion- and expression libraries. The effect of the expression level for - each gene on fitness will be quantified through precise high throughput growth rate measurements. We will dissect general cellular cost-factors from gene specific effects which allow us to systematically uncover the mechanistic causes of the cost of - protein overexpression. The burden manifests in universal protein biosynthesis costs but also specific costs such as eventual detrimental effects. The benefits are determined by the function of a protein: metabolic activity, structural component, and - other roles. We will test if these contributions collectively converge to an optimum to maximize fitness. Optimality is a common objective in man-made systems and engineering and it will be intriguing to learn how natural selection has shaped cells - according to this concept. - - 2019-01-31, ongoing project - - - 2017-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - OPTEX - - - H2020-MSCA-IF-2015 - - - 707352 - - - - - THE UNIVERSITY OF SUSSEX - - - EUR 195 454,80 - - - A Quantum Boost for Atomic Sensors - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Atom interferometry provides extremely sensitive measurements of quantities such as rotations and accelerations. This project will theoretically investigate how quantum entanglement between atoms and photons can enhance the - sensitivity of atom-interferometry. The aim of this project is to drastically enhance the sensitivity of atom interferometers, to deliver practical sensing devices of unprecedented sensitivity. This increased sensitivity may lead to new technologies, - such as ultra-sensitive gravity gradiometers for the detection of mineral reserves, as well as important applications to fundamental physics, such as tests of fundamental theories beyond the standard model. - - 2018-08-08, ongoing project - - - 2016-08-09 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - QBAS - - - H2020-MSCA-IF-2015 - - - 704672 - - - - - NATIONAL UNIVERSITY OF IRELAND GALWAY - - - EUR 175 866 - - - Mathematical modelling of soft tissues - - - EUR 175 866 - - - Ireland - - - Higher or Secondary Education Establishments - - Dr Valentina Balbi is an Italian national, trained in Applied Mathematics in Italy and in Mechanics in France and at Stanford University. She publishes articles in high-impact factor journals, at the frontiers of applied - mathematics and other disciplines. She is requesting funds for two years, to work with Professor Michel Destrade and join his group of Biomechanics at NUI Galway, Ireland. - - 2019-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Ireland - - - SOFT-TISSUES - - - H2020-MSCA-IF-2015 - - - 705532 - - - - - THE UNIVERSITY OF SUSSEX - THE UNIVERSITY OF SUSSEX - UNIVERSITY OF BRISTOL - - - EUR 149 170 - - - DHaptics: Creating silent and sharp Mid-air Haptics using phased array of ultrasound transducers - - - EUR 149 170 - - - United Kingdom - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - A fundamental shift is underway in how we interact with our computers and devices. Products such as Microsoft’s Kinect and Leap Motion’s desktop controller enable us to dispose of the keyboard and mouse and instead control our - devices without touching them. Touchless sensing products are being launched across the consumer electronics, automotive and healthcare industries. A significant and well noted problem with touchless sensing is a lack of tactile feedback. - - 2016-05-31, closed project - - - 2014-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2014 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - DHaptics - - - ERC-2014-PoC - - - 640749 - - - - - BCAM - BASQUE CENTER FOR APPLIED MATHEMATICS - - - EUR 158 121,60 - - - Forecast of time-varying effects of post-GFC monetary policy + a novel computing application - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - Central banks worldwide routinely use models in assessing and forecasting the global and domestic economic outlook in order to determine the most suitable monetary policies. Economies evolve over time and policies that worked - in the 1980s might not be viable at the present time, thus models must be flexible to account for these changes. Undoubtedly, it is difficult to identify the exact point in time when a change in macroeconomic behaviour occurs, particularly a change - that will trigger a reactive monetary policy to neutralise its negative effects. The current project proposes a new methodology, which due to its local nature can react faster to changes in the process than other existing methodologies. This project - aims at breaking new ground in several respects. First, by proposing for the first time a nonparametric local linear estimator of multivariate processes with possible smooth or abrupt changes in the parameters. Second, by developing a user-friendly - computational package with the aforementioned functionality. Finally, by investigating the effect for G7 and Eurozone economies of the monetary policies driven by the global financial crisis. - - 2018-01-19, closed project - - - 2016-01-20 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - Post-GFC Monetary Policy - - - H2020-MSCA-IF-2014 - - - 657182 - - - - - HELMHOLTZ ZENTRUM POTSDAM DEUTSCHESGEOFORSCHUNGSZENTRUM GFZ - UNIVERSITETET I OSLO - Eidgenössische Technische Hochschule Zürich - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - UNIVERSITA DEGLI STUDI ROMA TRE - UNIVERSITY OF DURHAM - UNIVERSITEIT UTRECHT - THE UNIVERSITY OF EDINBURGH - UNIVERSITE DE MONTPELLIER - UNIVERSITE DE RENNES I - - - EUR 3 910 105,80 - - - Understanding subduction zone topography through modelling of coupled shallow and deep processes - - - EUR 3 910 105,80 - - - Germany - Norway - Switzerland - Spain - Italy - United Kingdom - Netherlands - United Kingdom - France - France - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The SUBITOP ETN is a framework for training and career development of young researchers in Geodynamics, Geophysics, Geology and Geomorphology. It has a scientific focus on the dynamics of continental margins where tectonic - plates are recycled through subduction. Subduction processes have shaped and govern many aspects of the topography of Europe, and other continents, and they determine the patterns and intensity of geological hazards such as earthquakes, volcanic - activity and landsliding. The Training Network will imbue 15 young scientists with the ability to address the links between the geological processes within subduction zones and the processes that impact the Earth’s surface above, using a - comprehensive range of modelling and observation techniques and exploiting the full diversity of active and ancient subduction systems within Europe. - - 2020-02-29, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - SUBITOP - - - H2020-MSCA-ITN-2015 - - - 674899 - - - - - PHILIPPS UNIVERSITAET MARBURG - - - EUR 159 460,80 - - - Functional characterization of the cell division inhibitor MipZ - - - EUR 159 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - Correct positioning of the division plane is essential for the generation of normal offspring. In Caulobacter crescentus, the spatiotemporal control of cell division is mediated by MipZ, a conserved P-loop ATPase forming - bipolar gradients with a concentration minimum at the cell centre. Antagonizing the polymerization of the essential divisome component FtsZ, MipZ inhibits divisome assembly near the poles, thereby limiting cytokinesis to midcell. Gradient formation - involves a dynamic localization cycle, in which freely diffusible MipZ monomers interact with polar complexes of the centromere-binding protein ParB and then dimerize in an ATP-dependent manner. Dimers dissociate from ParB and are immobilized within - the cell through non-specific interaction with chromosomal DNA. Spontaneous ATP hydrolysis triggers disassembly of the complex, releasing MipZ monomers that are recaptured by ParB. How ParB stimulates dimer formation and how DNA-bound dimers inhibit - FtsZ assembly is still unknown. We will address these questions by characterizing previously isolated MipZ mutants with FtsZ/ParB interaction defects, using a combination of fluorescence microscopy, two-hybrid analysis, biochemistry, and biophysical - techniques such as surface plasmon resonance, microscale thermophoresis or hydrogen-deuterium-exchange mass spectrometry. We will also use synthetic biological and modelling approaches to rebuild the system in a simplistic form to thus gain in-depth - knowledge of the function of the different elements. - - 2017-08-02, closed project - - - 2015-08-03 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - MIPZ - - - H2020-MSCA-IF-2014 - - - 659174 - - - - - HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF EV - - - EUR 171 460,80 - - - Selective recovery of gallium from wastewaters of GaAs fabrication industry using siderophore based bisorptive biocomposites - - - EUR 171 460,80 - - - Germany - - - Research Organisations - - The projected use of GaAs and CIGS solar panel will lead to 137 tonnes deficit of Ga in 2020. As the Ga can only be economically mined as a by-product of bauxite mining which is not going to increase dramatically in near - future, the only way to meet the projected EU requirement is by the recovery of Ga from scraps (LED waste) or GaAs fabrication industry wastewater. However, there is so far no commercially viable technology available. - - 2018-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - GaLIophore - - - H2020-MSCA-IF-2015 - - - 704852 - - - - - ETHNIKO IDRYMA EREVNON - - - EUR 164 653,20 - - - Distributed vibrational and acoustic sensing technology - - - EUR 164 653,20 - - - Greece - - - Research Organisations - - The main target of the DIVAS project is the design and development of a low-cost opto-electronic interrogator for distributed vibration detection on standard communication optical fibers, based on Phase-OTDR technology - (Phase-sensitive Optical Time Domain Reflectometry). This system is compatible with communication optical fiber devices, and it takes the advances of this innovating field. It will be developed through custom design of a set of electronic and - optoelectronic components. Its distributed feature allows the collection of vibrational information along the entire optical fiber length, which is equivalent to thousands and thousands of inline sensors. This feature combined with extreme - sensitivity, makes this interrogator an efficient low-price option in vibration detections. For reasons of cost effectiveness, communication optical fiber lines are, normally, adjacent to strategic buildings such us railway, gas, and petrol lines; - using one of the available redundant optical fibers, it is possible to retrieve vibrational information for seismic security or for civil structural health monitoring. Using also specifically installed optical fibers, this interrogator may have a - wide range of applications from environmental protection purposes (such as terrestrial fauna and marine life protection), to control of intrusions in a wide area (e.g. military context) or, finally, for security purposes such as monitoring nuclear - power plants (in order to know if structural damages are approaching before a leakage occurs). The project aims for the development of a compact portable prototype, ready for field tests, which will be tried on at least in one civil engineering - application (structural health monitoring), in collaboration with the academic partner. With the help of the industrial partner, the prototype will be adapted for the production line to reach the market with a competitive cost that will ensure its - widespread dissemination in all possible fields. - - 2018-06-07, ongoing project - - - 2016-06-08 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Greece - - - DIVAS - - - H2020-MSCA-IF-2015 - - - 706221 - - - - - UNIVERSITAET ZU KOELN - UNIVERSITAET ZU KOELN - - - EUR 1 683 120 - - - Using cis-regulatory mutations to highlight polygenic adaptation in natural plant systems - - - EUR 1 683 120 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The goal of this project is to demonstrate that novel aspects of the molecular basis of Darwinian adaptation can be discovered if the polygenic basis of adaptation is taken into account. This project will use the genome-wide - distribution of cis-regulatory variants to discover the molecular pathways that are optimized during adaptation via accumulation of small effect mutations. Current approaches include scans for outlier genes with strong population genetics signatures - of selection, or large effect QTL associating with fitness. They can only reveal a small subset of the molecular changes recruited along adaptive paths. Here, instead, the distribution of small effect mutations will be used to make inferences on the - targets of polygenic adaptation across divergent populations in each of the two closely related species, A. thaliana and A. lyrata. These species are both found at diverse latitudes and show sign of local adaptation to climatic differences. Mutations - affecting cis-regulation will be identified in leaves of plants exposed to various temperature regimes triggering phenotypic responses of adaptive relevance. Their distribution in clusters of functionally connected genes will be quantified. The - phylogeographic differences in the distribution of the mutations will be used to disentangle neutral from adaptive clusters of functionally connected genes in each of the two species. This project will identify the molecular pathways subjected - collectively to natural selection and provide a completely novel view on adaptive landscapes. It will further examine whether local adaptation occurs by convergent evolution of molecular systems in plants. This approach has the potential to find - broad applications in ecology and agriculture. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - AdaptoSCOPE - - - ERC-2014-CoG - - - 648617 - - - - - THE UNIVERSITY OF SHEFFIELD - - - EUR 251 857,80 - - - Engineered Near-Infrared Photosynthesis - - - EUR 251 857,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Sunlight is the most abundant and sustainable energy source available to us. It drives photosynthesis, the source of all food and most energy resources on Earth. Phototrophic organisms use antenna complexes to absorb solar - energy, and derived excitation energy migrates towards specialised pigment-protein complexes called reaction centres. Here, photosynthetic electron transfer is initiated, converting solar energy into a form that can be stored and used to power cell - metabolism. The absorption characteristics of antenna and reaction centre complexes determine the specific wavelengths of light that can be captured and converted into chemical energy; light at other wavelengths is not used, representing a major - limitation of light-harvesting efficiency. Improving this efficiency will play a key role in ensuring food and energy security for the future, a societal challenge to be met by the H2020 programme. - - 2018-11-30, ongoing project - - - 2015-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - EngiNear-IR - - - H2020-MSCA-IF-2014 - - - 660652 - - - - - NATIONAL UNIVERSITY OF IRELAND GALWAY - - - EUR 248 063,40 - - - Bioelectroreduction of nitrogen to ammonia: the incorporation of nitrogenase within enzymatic biological fuel cells for simultaneous production of electrical energy and ammonia. - - - EUR 248 063,40 - - - Ireland - - - Higher or Secondary Education Establishments - - Enzymatic biological fuel cells (EBFCs) utilise enzymes as biological catalysts to produce electrical energy from chemical energy, usually being fuelled by simple molecules such as glucose or ethanol, in the presence of O2. - This technology provides an alternative to the use of expensive metal catalysts (such as platinum) and offers the ability for electrical energy to be produced under much milder conditions, such as near-neutral pH and room temperature. The cathodes of - EBFCs usually employ O2 as the oxidant and final electron acceptor; this proposal seeks to utilise N2 in its place. Not only does the use of N2 as the oxidant circumvent issues relating to dissolved O2 concentrations and solubility (limited to less - than 1 mM), but it also presents the possibility to produce industrially important NH3 (using a novel technology) whilst simultaneously producing electrical energy. - - 2018-05-31, ongoing project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Ireland - - - Bioelectroammonia - - - H2020-MSCA-IF-2014 - - - 654836 - - - - - UNIVERSITAET BIELEFELD - UNIVERSITA DEGLI STUDI DELL'INSUBRIA - EOTVOS LORAND TUDOMANYEGYETEM - HELSINGIN YLIOPISTO - UNIVERSITA DEGLI STUDI DI MILANO - UNIVERSITAET ZU KOELN - Orszagos Onkologiai Intezet - HEIDELBERG PHARMA GMBH - EXIRIS SRL - - - EUR 3 746 420,28 - - - Peptide-Drug Conjugates for Targeted Delivery in Tumor Therapy - - - EUR 3 746 420,28 - - - Germany - Italy - Hungary - Finland - Italy - Germany - Hungary - Germany - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Many tumor cells are characterized by the overexpression of certain antigens. Molecules that specifically recognize these structures are suitable as homing devices in tumor therapy. Conjugates of anticancer drugs with such a - delivery vector targeting tumors would be a “magic bullet” according to the Nobel laureate Paul Ehrlich. Three antibody-drug conjugates (ADC) have already been approved for anticancer therapy. However, ADC have e.g. limitations with respect to tumor - penetration, high manufacturing costs, and require challenging conjugation chemistry. Peptide-drug conjugates can have a high drug loading, easily penetrate tissue, and can be easily prepared in a homogenous form with straightforward and well-defined - conjugation chemistry. - - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - MAGICBULLET - - - H2020-MSCA-ITN-2014 - - - 642004 - - - - - THE UNIVERSITY OF SUSSEX - THE UNIVERSITY OF SUSSEX - - - EUR 149 645 - - - The development, evaluation and commercialisation of an early years test of colour vision deficiency. - - - EUR 149 645 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Colour vision deficiency (CVD) is a genetic disorder of colour vision that affects 7.4% of European males and 0.4% of European females. Although there are reliable tests for diagnosing CVD in adults and older children, there - are only a few tests for young children, and fundamental issues with these tests render them unreliable. For example, colours used in the tests are too similar for young children to discriminate given their immature colour vision, tasks are too - difficult for them to complete, tests either over- or under-diagnose CVD, or are not widely accessible. Therefore, the current situation is that CVD can be reliably diagnosed only from about 5 years onwards. Earlier diagnosis would enable steps to be - taken to ensure CVD children are not disadvantaged in early years education that relies on colour coded schemes and materials. Our goal is to develop, evaluate and bring to market an age-appropriate early years test for CVD. Our research on the ERC - funded ‘CATEGORIES’ project is investigating the development of colour perception in over 1400 infants and toddlers. This extensive testing has given us specialist insight into the exact colours that are appropriate for an early years test for CVD. - We have also developed age-appropriate tasks that measure young children’s responses to colour in a reliable and efficient manner. In the current project we propose to develop an early years CVD test in the form of an app. The test will use the - colours that we have defined and the tasks that we have developed, and we aim for it to provide an accurate CVD diagnosis. The project will take the test to proof of concept and will establish the scientific validity, technical feasibility and - commercialisation process. We aim that the test will be the ‘gold standard’ for educators, clinicians, scientists and parents. This will ensure that CVD can be detected earlier than is currently the case, bringing important and tangible benefits for - education, clinical practice and research. - - 2018-05-31, ongoing project - - - 2016-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2015 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - COLOURTEST - - - ERC-2015-PoC - - - 692694 - - - - - Teknologian tutkimuskeskus VTT Oy - AALTO-KORKEAKOULUSAATIO - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - RISE PROCESSUM AB - KUNGLIGA TEKNISKA HOEGSKOLAN - STIFTELSEN SINTEF - INSTITUT TECHNOLOGIQUE FCBA (FORETCELLULOSE BOIS-CONSTRUCTION AMEUBLEMENT) - INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE - FUNDACION TECNALIA RESEARCH & INNOVATION - KOMPETENZZENTRUM HOLZ GMBH - LATVIJAS VALSTS KOKSNES KIMIJAS INSTITUTS - INSTITUTUL DE CHIMIE MACROMOLECULARA PETRU PONI - BIO BASE EUROPE PILOT PLANT VZW - - - EUR 2 628 700 - - - Research Infrastructure for Circular Forest Bioeconomy - - - EUR 2 630 950 - - - Finland - Finland - Germany - Sweden - Sweden - Norway - France - France - Spain - Austria - Latvia - Romania - Belgium - - - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Other - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Other - - The ERIFORE will realize the European potential to consolidate its place as a world leader in biomass based research and innovations. ERIFORE builds on a new firm alliance aiming to establish open access distributed forest - bioeconomy research infrastructure across Europe enabling scientific discoveries to be transferred to new business models, novel products and services enabling sustainable growth. The research infrastructure will focus on topics supporting Circular - Forest Bioeconomy concepts starting from fundamental teaching and knowledge sharing to high level research laboratories and large scale piloting facilities. - - 2018-01-31, closed project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-1-2014 - Design studies - - - CSA - Coordination and support action - - - Finland - - - ERIFORE - - - H2020-INFRADEV-1-2014-1 - - - 654371 - - - - - THE UNIVERSITY OF SUSSEX - UMEA UNIVERSITET - UNIVERSIDAD DE SEVILLA - ROMA OKTATASI ALAP - - - EUR 207 000 - - - Higher Education Internationalisation and Mobility: Inclusion, Equalities and Innovations - - - EUR 207 000 - - - United Kingdom - Sweden - Spain - Hungary - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - - The proposed research/innovation project (HEIM) focuses on how principles of equity and inclusion can be applied to internationalisation strategies and programmes in higher education, at both staff and student levels. It - focuses on the Roma community in Europe as a critical example of a marginalised group. HEIM will interrogate and develop the concept and practices of higher education internationalisation in Europe through questions about who is able to participate - in and benefit from policy initiatives and strategic interventions. It asks whether certain social groups are disadvantaged or excluded from the opportunities that mobility offers. It will examine motivations and experiences, and the hidden costs of - border crossings in terms of socio-political and affective considerations. Its objectives include comparative investigation of data on who is participating in selected internationalisation programmes; producing accounts based on literature, - statistical data and empirical research. It will create a set of guidelines for reflexive and inclusive approaches to the internationalisation of higher education. Through its interdisciplinary and intersectoral approaches, it will contribute to - methodological innovation across different fields. It will build research and innovation capacity by constructing teams and sharing knowledge between early stage and experienced researchers. It will exchange knowledge about internationalisation - programmes in the partner organisations via co-written papers, statistical datasets, literature reviews, training and workshops. The Partnership is between three universities (Sussex, Umeå and Seville) and a non-academic organisation, the Roma - Education Fund (REF). Via secondments, staff exchange, training and collaborative inquiry, the project will investigate internationalisation policies, interventions and methodologies in different national locations. - - 2017-12-31, closed project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - United Kingdom - - - HEIM - - - H2020-MSCA-RISE-2014 - - - 643739 - - - - - WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER - THE UNIVERSITY OF EDINBURGH - KAROLINSKA INSTITUTET - CHARITE - UNIVERSITAETSMEDIZIN BERLIN - SEREND-IP GMBH - AQUILA BIOMEDICAL LIMITED - REPRODUKTIIVMEDITSIINI TAK AS - - - EUR 346 500 - - - Molecular Mechanisms of Endometriosis - - - EUR 346 500 - - - Germany - United Kingdom - Sweden - Germany - Germany - United Kingdom - Estonia - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Endometriosis (the presence of endometrial-like tissue or ‘lesions’ outside the uterus) is a chronic inflammatory disease affecting 6-10% of reproductive age women. It is associated with pelvic pain, painful periods, pain with - sexual intercourse, and subfertility. The socioeconomic impacts of endometriosis are considerable. The recent WERF EndoCost study (a worldwide cost-of-illness study) reported that endometriosis reduced work productivity in 51% and negatively affected - relationships in 50% of women with endometriosis. Current treatment options include invasive and repeated surgeries, or hormonal suppression with significant side effects analogous to a premature menopause. While several general concepts of the - etiology of the disease such as retrograde menstruation, coelomic metaplasia, lymphovascular metastasis or the embryonic rest theory have been developed, the molecular mechanisms underlying the disease are currently still incompletely understood, - hampering the development of efficient targeted therapies with limited side effects. MOMENDO utilizes the potential of an interdisciplinary consortium of leading world endometriosis experts to provide a deeper understanding of key molecular processes - contributing to disease etiology and progression. By employing a wide range of experimental methods (biomarker and epigenetic studies on patient tissues, advanced animal models of the disease, proprietary atomic force microscopy for marker-free - diagnostics) and novel and innovative conceptual approaches (adult stem cells, microRNAs, iron-induced inflammatory responses, novel endocrine concepts), MOMENDO will substantially contribute to a deeper understanding of the molecular mechanisms that - explain the inflammatory pain associated with endometriosis and the persistent growth of endometriosis lesions. By combining the respective strengths of non-academic and clinical partners, MOMENDO expect to successfully translate these findings into - novel therapeutic approaches. - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Germany - - - MOMENDO - - - H2020-MSCA-RISE-2015 - - - 691058 - - - - - CENTRE D ESTUDIS DEMOGRAFICS - - - EUR 239 191,20 - - - Family formation decisions and gender attitudes in crisis times: an international, historical and longitudinal comparison. - - - EUR 239 191,20 - - - Spain - - - Research Organisations - - During the last decades, Spain has experienced not only an strong decrease on its fertility levels but also a significant delay in its timing to childbearing, so much so that it has been considered one of the countries with - the lowest-low and latest-late fertility in the world. This research aims to better understand the reasons behind young adults’ behaviors in family dynamics in a moment where it is possible to approach the impact of the economic crisis from different - dimensions of the analysis. An extended scientific literature can be found about family formation dynamics and fertility, especially for European countries and mainly using a quantitative perspective. This mainly qualitative project proposes an - innovative methodology to analyze the Spanish case from a three different perspectives of analysis: a cross-country comparison (five countries in 2012), an historical comparison (Spain 1985 vs. 2012) and a longitudinal comparison (Spain, same sample - in 2012 and 2017). Furthermore, mixed methods will be applied considering the contextualization of qualitative data with quantitative data from census and surveys as complementary approaches; and the application of quantitative analysis to - qualitative data. Main data from Spain in 2012 comes directly from the words of young adults in three different moments of their family formation decisions: i) to start a stable relationship; ii) to become parents; and iii) to expand the family after - the first child. Main data consists of eighty (80) in-depth personal interviews already carried out to young adults between 24 and 35 years old, living in the Madrid and Barcelona metropolitan areas, that will be compared with an identical sample in - the US, Sweden, Japan and Korea. Historical data comes from an existing comparable study from middle 80’s in Spain and longitudinal data will be obtained after re-interview in 2017 the same sample interviewed in 2012 for Spain. - - 2019-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Spain - - - FAMilyDECisions - - - H2020-MSCA-IF-2014 - - - 657030 - - - - - INSTITUTO DE ASTROFISICA DE CANARIAS - ISTITUTO NAZIONALE DI ASTROFISICA - UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - STOCKHOLMS UNIVERSITET - THE QUEEN'S UNIVERSITY OF BELFAST - UNIVERSITY COLLEGE LONDON - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - CONSIGLIO NAZIONALE DELLE RICERCHE - INSTITUTO NACIONAL DE TECNICA AEROESPACIAL ESTEBAN TERRADAS - A.D.S. INTERNATIONAL SRL - ARCOPTIX SA - ANDOR TECHNOLOGY LIMITED - - - EUR 2 977 273 - - - Getting Ready for EST - - - EUR 3 956 730 - - - Spain - Italy - Italy - Germany - Sweden - United Kingdom - United Kingdom - Spain - Italy - Spain - Italy - Switzerland - United Kingdom - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The present project is intended to take the European Solar Telescope (EST) to the next level of development by undertaking crucial activities to improve the performance of current state-of-the-art instrumentation. Legal, - industrial and socio-economic issues will also be addressed, as key questions for the attainment of EST. The particular developments and strategic tasks proposed here can be summarised in the following specific objectives: - - 2018-05-31, ongoing project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-1-2014 - Design studies - - - RIA - Research and Innovation action - - - Spain - - - GREST - - - H2020-INFRADEV-1-2014-1 - - - 653982 - - - - - UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA - BCAM - BASQUE CENTER FOR APPLIED MATHEMATICS - INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE - BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION - TOTAL S.A. - - - EUR 580 500 - - - Geophysical Exploration using Advanced GAlerkin Methods - - - EUR 580 500 - - - Spain - Spain - France - Spain - France - - - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The main objective of this Marie Curie RISE action is to improve and exchange interdisciplinary knowledge on applied mathematics, high performance computing, and geophysics to be able to better simulate and understand the - materials composing the Earth's subsurface. This is essential for a variety of applications such as CO2 storage, hydrocarbon extraction, mining, and geothermal energy production, among others. All these problems have in common the need to obtain an - accurate characterization of the Earth's subsurface, and to achieve this goal, several complementary areas will be studied, including the mathematical foundations of various high-order Galerkin multiphysics simulation methods, the efficient computer - implementation of these methods in large parallel machines and GPUs, and some crucial geophysical aspects such as the design of measurement acquisition systems in different scenarios. - - - 2017-12-31, closed project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Spain - - - GEAGAM - - - H2020-MSCA-RISE-2014 - - - 644202 - - - - - THE UNIVERSITY OF SUSSEX - THE UNIVERSITY OF SUSSEX - - - EUR 149 630 - - - HeartRater: Tools for the systematic evaluation of interoceptive ability - - - EUR 149 630 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The Proof-of-Concept grant seeks to develop a commercializable platform to quantify how sensitive individuals are to their own heartbeats. This platform will have applications in clinical psychology, personalized medicine and beyond. - - 2018-03-31, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2015 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - HeartRater - - - ERC-2015-PoC - - - 693143 - - - - - THE UNIVERSITY OF SUSSEX - UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6 - RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN - UNIVERSITA DEGLI STUDI DI CATANIA - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - UNIVERSITA DEGLI STUDI DELL'AQUILA - UNIVERSIDAD DE MALAGA - UNIVERSITETET I OSLO - - - EUR 3 918 484,14 - - - Modelling and Computation of Shocks and Interfaces - - - EUR 3 918 484,14 - - - United Kingdom - France - Germany - Italy - Greece - Italy - Spain - Norway - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The proposed ITN entitled "Modelling and computation of Shocks and Interfaces" will focus on the training of young researchers in the general area of nonlinear hyperbolic and convection dominated PDEs with emphasis on - innovative modelling and computational methods. - - 2019-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - ModCompShock - - - H2020-MSCA-ITN-2014 - - - 642768 - - - - - UNIVERSIDADE DO PORTO - UNIVERSITA DEGLI STUDI DI MILANO - NATIONAL UNIVERSITY OF IRELAND GALWAY - UNIVERSITA DEGLI STUDI DI PERUGIA - - - EUR 720 000 - - - Sexual Plant Reproduction – Seed formation - - - EUR 751 500 - - - Portugal - Italy - Ireland - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - By 2050, it is estimated that the human population will reach 9 billion. To feed this growing population, it will be necessary to at least double agricultural yields, without increasing the amount of arable land. - - - 2020-02-29, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Portugal - - - SexSeed - - - H2020-MSCA-RISE-2015 - - - 690946 - - - - - HAROKOPIO UNIVERSITY - QUEEN MARY UNIVERSITY OF LONDON - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - CONSIGLIO NAZIONALE DELLE RICERCHE - FUNDACION PARA EL FOMENTO DE LA INVESTIGACION SANITARIA Y BIOMEDICA DE LA COMUNITAT VALENCIANA - BIOTECH VANA SL - Randox Laboratories Ltd - MARASCIO FERNANDO - SANOFI-AVENTIS DEUTSCHLAND GMBH - ENOSIS MASTICHOPARAGOGON CHIOU - PERSPECTUM DIAGNOSTICS LTD - Univerzitet u Novom Sadu - Medicinski fakultet - UNIVERZITET U ISTOCNOM SARAJEVU - - - EUR 2 124 000 - - - Mastiha treatment for healthy obese with NAFLD diagnosis (MAST4HEALTH). - - - EUR 2 124 000 - - - Greece - United Kingdom - France - Italy - Spain - Spain - United Kingdom - Italy - Germany - Greece - United Kingdom - Serbia - Bosnia and Herzegovina - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - MAST4HEALTH is set on the concept of a multidisciplinary approach to assess a non-pharmacological intervention for managing NAFLD/NASH, one of the most common complications of obesity and diabetes mellitus in Western - populations affecting approximately 50% of diabetics and 76% of obese patients. Because of limitations in current NAFLD treatment therapies, many new efforts focus on exploring non-pharmacologic means for managing the disease and in particular - through dietary substances or bioactive phytochemicals in fruits, vegetables, and plants or their products. MAST4HEALTH aims at exploring the effect of Mastiha, a natural product of Greece which was recently shown to possess - antioxidant/anti-inflammatory and lipid lowering properties. We designed a multicenter randomized double blind placebo controlled (parallel arm) clinical trial to test the effectiveness of Mastiha supplement as new non-pharmacologic strategy for - NAFLD/NASH treatment. MAST4HEALTH will explore gene-diet interactions, more specifically the potential personalized activity of the Mastiha, and correlate genetic and epigenetic markers with metabolomic and intestinal microbiota profiles pre- and - post-intervention. The effectiveness of the proposed intervention will be evaluated via clinical and laboratory markers of the disease. To this end, MAST4HEALTH will train a number of researchers and PhD students in multidisciplinary approaches of - this survey. MAST4HEALTH is expected to build and enhance cooperation among partners meanwhile strengthening the interaction between our academic and non-academic sectors - - 2020-02-29, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Greece - - - MAST4HEALTH - - - H2020-MSCA-RISE-2015 - - - 691042 - - - - - NATURAL ENVIRONMENT RESEARCH COUNCIL - MARIENE INFORMATIE SERVICE MARIS BV - ISTITUTO NAZIONALE DI OCEANOGRAFIA E DI GEOFISICA SPERIMENTALE - INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER - HELLENIC CENTRE FOR MARINE RESEARCH - AGENZIA NAZIONALE PER LE NUOVE TECNOLOGIE, L'ENERGIA E LO SVILUPPO ECONOMICO SOSTENIBILE - UNIVERSITE DE LIEGE - CONSIGLIO NAZIONALE DELLE RICERCHE - INSTITUT ROYAL DES SCIENCES NATURELLES DE BELGIQUE - NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO - ALFRED-WEGENER-INSTITUT HELMHOLTZ-ZENTRUM FUR POLAR- UND MEERESFORSCHUNG - BUNDESAMT FUR SEESCHIFFFAHRT UND HYDROGRAPHIE - ALL-RUSSIAN RESEARCH INSTITUTE OF HYDROMETEOROLOGICAL INFORMATION-WORLD DATA CENTRE - VLAAMS INSTITUUT VOOR DE ZEE VZW - UNIVERSITAET BREMEN - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - 52°North Initiative for Geospatial Open Source Software GmbH - IEEE FRANCE SECTION - SOCIB - CONSORCIO PARA EL DISENO, CONSTRUCCION, EQUIPAMIENTO Y EXPLOTACION DEL SISTEMA DE OBSERVACION COSTERO DE LAS ILLES BALEARS - - - EUR 1 912 086,25 - - - Extending the Ocean Data Interoperability Platform - - - EUR 1 912 086,25 - - - United Kingdom - Netherlands - Italy - France - Greece - Italy - Belgium - Italy - Belgium - Netherlands - Germany - Germany - Russia - Belgium - Germany - Spain - Germany - France - Spain - - - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Other - Other - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - The Ocean Data Interoperability Platform project is promoting the development of a common global framework for marine data management by developing interoperability between existing regional e-infrastructures. Through a series - of international workshops attracting relevant domain experts a number of prototype interoperability solutions will be developed which will be implemented by the regional data infrastructures to provide users with open access to good quality - multidisciplinary data and associated services. Improved access to a range of marine data will facilitate re-use of the data and support researchers in addressing grand challenges such as climate change and conservation of marine resources. - - 2018-03-31, ongoing project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.3.2."> - - - INFRASUPP-6-2014 - International cooperation for research infrastructures - - - CSA - Coordination and support action - - - United Kingdom - - - ODIP 2 - - - H2020-INFRASUPP-2014-2 - - - 654310 - - - - - EUROPEAN MOLECULAR BIOLOGY LABORATORY - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - EARLHAM INSTITUTE - THE UNIVERSITY OF MANCHESTER - TARTU ULIKOOL - Stichting Netherlands Bioinformatics Centre - FUNDACION CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III - FUNDACIO CENTRE DE REGULACIO GENOMICA - FUNDACION DE LA COMUNIDAD VALENCIANA CENTRO DE INVESTIGACION PRINCIPEFELIPE - FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA) - UNIVERSIDAD DE MALAGA - BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - UNIVERSIDAD POMPEU FABRA - FUNDACIO INSTITUT MAR D INVESTIGACIONS MEDIQUES IMIM - FUNDACAO CALOUSTE GULBENKIAN - INESC ID - INSTITUTO DE ENGENHARIADE SISTEMAS E COMPUTADORES, INVESTIGACAO E DESENVOLVIMENTO EM LISBOA - INSTITUTO DE BIOLOGIA EXPERIMENTAL E TECNOLOGICA - CENTRO DE CIENCIAS DO MAR DO ALGARVE - CSC-TIETEEN TIETOTEKNIIKAN KESKUS OY - UNIVERSITETET I BERGEN - NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU - UNIVERSITETET I TROMSOE - UNIVERSITETET I OSLO - SWISS INSTITUTE OF BIOINFORMATICS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE - CENTRE DE COOPERATION INTERNATIONALE EN RECHERCHE AGRONOMIQUE POUR LEDEVELOPPEMENT - C.I.R.A.D. EPIC - INSTITUT PASTEUR - CONSIGLIO NAZIONALE DELLE RICERCHE - LINKOPINGS UNIVERSITET - UNIVERZA V LJUBLJANI - NACIONALNI INSTITUT ZA BIOLOGIJO - USTAV ORGANICKE CHEMIE A BIOCHEMIE, AV CR, V.V.I. - Masarykova univerzita - CESNET ZAJMOVE SDRUZENI PRAVNICKYCH OSOB - VIB - DANMARKS TEKNISKE UNIVERSITET - BIOMEDICAL SCIENCES RESEARCH CENTER ALEXANDER FLEMING - THE HEBREW UNIVERSITY OF JERUSALEM - ATHINA-EREVNITIKO KENTRO KAINOTOMIAS STIS TECHNOLOGIES TIS PLIROFOFORIAS, TON EPIKOLNONION KAI TIS GNOSIS - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - THE UNIVERSITY OF EDINBURGH - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 19 051 482 - - - ELIXIR-EXCELERATE: Fast-track ELIXIR implementation and drive early user exploitation across the life-sciences. - - - EUR 19 051 482 - - - Germany - United Kingdom - United Kingdom - United Kingdom - Estonia - Netherlands - Spain - Spain - Spain - Spain - Spain - Spain - Spain - Spain - Spain - Portugal - Portugal - Portugal - Portugal - Finland - Norway - Norway - Norway - Norway - Switzerland - France - France - France - France - Italy - Sweden - Slovenia - Slovenia - Czech Republic - Czech Republic - Czech Republic - Belgium - Denmark - Greece - Israel - Greece - Greece - United Kingdom - United Kingdom - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Other - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The life sciences are undergoing a transformation. Modern experimental tools study the molecules, reactions, and organisation of life in unprecedented detail. The precipitous drop in costs for high-throughput biology has - enabled European research laboratories to produce an ever-increasing amount of data. Life scientists are rapidly generating the most complex and heterogeneous datasets that science can currently imagine, with unprecedented volumes of biological data - to manage. - - 2019-08-31, ongoing project | - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-3-2015 - Individual implementation and operation of ESFRI projects - - - RIA - Research and Innovation action - - - Germany - - - ELIXIR-EXCELERATE - - - H2020-INFRADEV-1-2015-1 - - - 676559 - - - - - GRAND ACCELERATEUR NATIONAL D'IONS LOURDS - ISTITUTO NAZIONALE DI FISICA NUCLEARE - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH - JYVASKYLAN YLIOPISTO - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - GSI HELMHOLTZZENTRUM FUER SCHWERIONENFORSCHUNG Gmbh - RIJKSUNIVERSITEIT GRONINGEN - THE HENRYK NIEWODNICZANSKI INSTITUTE OF NUCLEAR PHYSICS, POLISH ACADEMY OF SCIENCES - UNIWERSYTET WARSZAWSKI - "INSTITUTUL NATIONAL DE CERCETARE -DEZVOLTARE PENTRU FIZICA SI INGINERIE NUCLEARA ""HORIA HULUBEI"" (IFIN-HH)" - FONDAZIONE BRUNO KESSLER - EBG (Entwicklungs- und Betriebsgesellschaft) MedAustron GmbH - KATHOLIEKE UNIVERSITEIT LEUVEN - UNIVERSITE LIBRE DE BRUXELLES - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - GROUPEMENT INTERET PUBLIC ARRONAX - JUSTUS-LIEBIG-UNIVERSITAET GIESSEN - JOHANNES GUTENBERG-UNIVERSITAT MAINZ - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - UNIVERSITAET ZU KOELN - "NATIONAL CENTER FOR SCIENTIFIC RESEARCH ""DEMOKRITOS""" - UNIVERSITA DEGLI STUDI DI MILANO - FUNDACAO DA FACULDADE DE CIENCIAS DA UNIVERSIDADE DE LISBOA FP - CENTRO DE INVESTIGACIONES ENERGETICAS, MEDIOAMBIENTALES Y TECNOLOGICAS-CIEMAT - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - UNIVERSIDAD DE SANTIAGO DE COMPOSTELA - UNIVERSIDAD DE SEVILLA - THE UNIVERSITY OF LIVERPOOL - UNIVERSITY OF YORK - Magyar Tudomanyos Akademia Atommagkutato Intezete - - - EUR 10 000 000 - - - European Nuclear Science and Application Research 2 - - - EUR 10 000 000 - - - France - Italy - Switzerland - Finland - France - Germany - Netherlands - Poland - Poland - Romania - Italy - Austria - Belgium - Belgium - France - France - Germany - Germany - Germany - Germany - Greece - Italy - Portugal - Spain - Spain - Spain - Spain - United Kingdom - United Kingdom - Hungary - - - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - ENSAR2 is the integrating activity for European nuclear scientists who are performing research in three of the major subfields defined by NuPECC: Nuclear Structure and Dynamics, Nuclear Astrophysics and Nuclear Physics Tools - and Applications. It proposes an optimised ensemble of Networking (NAs), Joint Research (JRAs) and Transnational Access Activities (TAs), which will ensure qualitative and quantitative improvement of the access provided by the current ten - infrastructures, which are at the core of this proposal. The novel and innovative developments that will be achieved by the RTD activities will also assure state-of-the-art technology needed for the new large-scale projects. - - 2020-02-29, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.2."> - - - INFRAIA-1-2014-2015 - Integrating and opening existing national and regional research infrastructures of European interest - - - RIA - Research and Innovation action - - - France - - - ENSAR2 - - - H2020-INFRAIA-2014-2015 - - - 654002 - - - - - UNIVERSITE D'AIX MARSEILLE - BERNHARD-NOCHT-INSTITUT FUER TROPENMEDIZIN - THE SECRETARY OF STATE FOR ENVIRONMENT, FOOD AND RURAL AFFAIRS - UNIVERSITAETSKLINIKUM BONN - Department of Health - UNIVERSITAET BASEL - UNIVERZA V LJUBLJANI - BIOMEDICINSKE CENTRUM SLOVENSKEJ AKADEMIE VIED - VIROLOGICKY USTAV SLOVENSKEJ AKADEMIE VIED - ISTITUTO NAZIONALE PER LE MALATTIE INFETTIVE LAZZARO SPALLANZANI-ISTITUTO DI RICOVERO E CURA A CARATTERE SCIENTIFICO - ROBERT KOCH-INSTITUT - ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM - ACADEMISCH ZIEKENHUIS LEIDEN - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - INSTITUT PASTEUR - FRIEDRICH LOEFFLER INSTITUT - BUNDESFORSCHUNGSINSTITUT FUER TIERGESUNDHEIT - THE PIRBRIGHT INSTITUTE LBG - AGRICULTURAL RESEARCH COUNCIL (ARC) - NATIONAL HEALTH LABORATORY SERVICES - FEDERAL STATE BUDGETARY SCIENTIFIC INSTITUTION CHUMAKOV INSTITUTE OF POLIOMYELITIS AND VIRAL ENCEPHALITIDES - SCIENTIFIC RESEARCH INSTITUTE OF INFLUENZA OF THE MINISTRY OF HEALTHCARE AND SOCIAL DEVELOPMENT OF THE RUSSIAN FEDERATION - RESEARCH INSTITUTE OF VACCINES AND SERA II MECHNIKOV - WUHAN INSTITUTE OF VIROLOGY, CHINESE ACADEMY OF SCIENCES - COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION - Folkhälsomyndigheten (The Public Health Agency of Sweden) - FONDATION MERIEUX - - - EUR 10 792 868 - - - European Virus Archive goes global - - - EUR 12 168 054,68 - - - France - Germany - United Kingdom - Germany - United Kingdom - Switzerland - Slovenia - Slovakia - Slovakia - Italy - Germany - Netherlands - Netherlands - France - France - Germany - United Kingdom - South Africa - South Africa - Russia - Russia - Russia - China - Australia - Sweden - France - - - Higher or Secondary Education Establishments - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - - The overall objective will be to create and mobilise an International network of high calibre centres around a strong European group of institutes selected for their appropriate expertises, to collect, amplify, characterise, - standardise, authenticate, distribute and track, mammalian and other exotic viruses. The network of EVAg laboratories including 25 institutions represents an extensive range of virological disciplines. The architecture of the consortium is based on - the association of capacities accessible to the partners but also to any end-users through the EVAg web-based catalogue. This concept has been elaborated and tested for its efficiency during the successful EVA project (FP7). The project will - integrate more facilities dedicated to high risk pathogen (HRP) manipulation (1 in EVA, 13 in EVAg) The access to products derived from those HRP will be enhanced and for instance the production of diagnostic reagents will be facilitated. The new - project will also provide access to high containment biosafety facilities to carry out in vivo studies of infectious disease using natural or models hosts, to look at prophylactic or therapeutic control measures and to develop materials for the - evaluation of diagnostic tests, meaning an extensive capacity to service and to training. EVAg will also link up with other network-based virus-associated programmes that exist globally. However, looking further ahead, EVAg is conceived ultimately to - be an open entity aiming at developing synergies and complementarity capabilities in such a way as to offer an improved access to researchers. This project will generate the largest collection of mammalian viruses in the world and move beyond the - current state-of-the-art to provide an increasingly valuable resource and service to the world’s scientific community, including government health departments, higher education institutes, industry and, through information systems, the general - public. - - 2019-03-31, ongoing project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.2."> - - - INFRAIA-1-2014-2015 - Integrating and opening existing national and regional research infrastructures of European interest - - - RIA - Research and Innovation action - - - France - - - EVAg - - - H2020-INFRAIA-2014-2015 - - - 653316 - - - - - CSC-TIETEEN TIETOTEKNIIKAN KESKUS OY - BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION - CENTRE EUROPEEN DE RECHERCHE ET DE FORMATION AVANCEE EN CALCUL SCIENTIFIQUE - CINECA CONSORZIO INTERUNIVERSITARIO - CINES - DEUTSCHES KLIMARECHENZENTRUM GMBH - UMWELTBUNDESAMT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (UBA GMBH) - EBERHARD KARLS UNIVERSITAET TUEBINGEN - THE UNIVERSITY OF EDINBURGH - ISTITUTO NAZIONALE DI GEOFISICA E VULCANOLOGIA - FORSCHUNGSZENTRUM JULICH GMBH - INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK - SURFSARA BV - UNINETT SIGMA AS - UNINETT SIGMA2 AS - SCIENCE AND TECHNOLOGY FACILITIES COUNCIL - UNIVERSITY COLLEGE LONDON - TRUST-IT SERVICES LIMITED - ETHNIKO DIKTYO EREVNAS TECHNOLOGIAS AE - KARLSRUHER INSTITUT FUER TECHNOLOGIE - STICHTING LIBER - KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW - E-SCIENCE DATA FACTORY - LUNDS UNIVERSITET - KONINKLIJK NEDERLANDS METEOROLOGISCH INSTITUUT-KNMI - HELMHOLTZ ZENTRUM POTSDAM DEUTSCHESGEOFORSCHUNGSZENTRUM GFZ - CLARIN ERIC - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - JISC LBG - UNIVERZITET U NOVOM SADU - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH - HELSINGIN YLIOPISTO - EUROPEAN MOLECULAR BIOLOGY LABORATORY - UPPSALA UNIVERSITET - BIOSENSE INSTITUTE - RESEARCH AND DEVELOPMENT INSTITUTE FOR INFORMATION TECHNOLOGIES IN BIOSYSTEMS - UNITED KINGDOM ATOMIC ENERGY AUTHORITY - - - EUR 18 865 385 - - - EUDAT2020 - - - EUR 19 052 882 - - - Finland - Spain - France - Italy - France - Germany - Austria - Germany - United Kingdom - Italy - Germany - Poland - Netherlands - Norway - Norway - United Kingdom - United Kingdom - United Kingdom - Greece - Germany - Netherlands - Netherlands - France - Sweden - Netherlands - Germany - Netherlands - Germany - United Kingdom - Serbia - Switzerland - Finland - Germany - Sweden - Serbia - United Kingdom - - - Other - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Other - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Other - Research Organisations - Research Organisations - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Other - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - - EUDAT2020 brings together a unique consortium of e-infrastructure providers, research infrastructure operators, and researchers from a wide range of scientific disciplines under several of the ESFRI themes, working together to - address the new data challenge. - - - 2018-02-28, ongoing project - - - 2015-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.3."> - - - EINFRA-1-2014 - Managing, preserving and computing with big research data - - - RIA - Research and Innovation action - - - Finland - - - EUDAT2020 - - - H2020-EINFRA-2014-2 - - - 654065 - - - - - INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE - HAVFORSKNINGSINSTITUTTET - THE UNIVERSITY OF STIRLING - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - HELLENIC CENTRE FOR MARINE RESEARCH - Nemzeti Agrarkutatasi es Innovacios Kozpont - INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER - NOFIMA AS - JIHOCESKA UNIVERZITA V CESKYCH BUDEJOVICICH - NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU - SINTEF FISKERI OG HAVBRUK AS - SINTEF OCEAN AS - UNIVERSIDAD DE LAS PALMAS DE GRAN CANARIA - WAGENINGEN UNIVERSITY - UNIVERSITEIT GENT - STICHTING WAGENINGEN RESEARCH - AquaTT UETP Ltd - INRA TRANSFERT S.A. - UNIVERSITE DE LORRAINE - DANMARKS TEKNISKE UNIVERSITET - CENTRO DE CIENCIAS DO MAR DO ALGARVE - INSTITUTO ESPANOL DE OCEANOGRAFIA - European Aquaculture Technology and Innovation Platform - - - EUR 9 708 867 - - - AQUAculture infrastructures for EXCELlence in European fish research towards 2020 - - - EUR 9 708 867 - - - France - Norway - United Kingdom - Spain - Greece - Hungary - France - Norway - Czech Republic - Norway - Norway - Norway - Spain - Netherlands - Belgium - Netherlands - Ireland - France - France - Denmark - Portugal - Spain - Belgium - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Other - - AQUAEXCEL2020 aims to integrate top class European aquaculture research facilities of very diverse nature, covering all relevant scientific fields for research and innovation in aquaculture, from genetics to technology through - pathology, physiology and nutrition. It will put in place a user-friendly one-stop access to high-quality services and resources from 39 installations covering both established and new aquaculture species, all types of experimental systems as well as - sequencing facilities. Giving a prominent place to EU aquaculture industry research needs through a strong involvement of the European Aquaculture Technology and Innovation Platform, it will enable excellent research and sustainable innovation to - both public and private sector. It will benefit from the support of the ESFRI infrastructures EMBRC (Marine Biology) and ELIXIR (Life Sciences data) and bring aquaculture research specificities to their agendas. - - 2020-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.2."> - - - INFRAIA-1-2014-2015 - Integrating and opening existing national and regional research infrastructures of European interest - - - RIA - Research and Innovation action - - - France - - - AQUAEXCEL2020 - - - H2020-INFRAIA-2014-2015 - - - 652831 - - - - - ARCTUR RACUNALNISKI INZENIRING DOO - NATIONAL UNIVERSITY OF IRELAND GALWAY - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK - ETHNIKO DIKTYO EREVNAS TECHNOLOGIAS AE - FUNDACION PUBLICA GALLEGA CENTRO TECNOLOGICO DE SUPERCOMPUTACION DE GALICIA - VYSOKA SKOLA BANSKA - TECHNICKA UNIVERZITA OSTRAVA - YOTTA ADVANCED COMPUTING DOO ZA ISTRAZIVANJE I USLUGE - UNIVERSITATEA DE VEST DIN TIMISOARA - INSTITUTE OF INFORMATION AND COMMUNICATION TECHNOLOGIES - RUDER BOSKOVIC INSTITUTE - HERCULESSTICHTING - FONDS VOOR WETENSCHAPPELIJK ONDERZOEK-VLAANDEREN - VILNIAUS UNIVERSITETAS - MEO-SERVICOS DE COMUNICACOES E MULTIMEDIA SA - HIGH PERFORMANCE COMPUTING WALES - BANGOR UNIVERSITY - - - EUR 1 998 363,75 - - - Supercomputing Expertise for SmAll and Medium Enterprise Network - - - EUR 1 998 363,75 - - - Slovenia - Ireland - Germany - Poland - Greece - Spain - Czech Republic - Croatia - Romania - Bulgaria - Croatia - Belgium - Belgium - Lithuania - Portugal - United Kingdom - United Kingdom - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Other - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Higher or Secondary Education Establishments - - Network of HPC Competence Centres for SMEs - - 2017-05-31, closed project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.3."> - - - EINFRA-6-2014 - Network of HPC Competence Centres for SMEs - - - CSA - Coordination and support action - - - Slovenia - - - SESAME NET - - - H2020-EINFRA-2014-2 - - - 654416 - - - - - DEUTSCHES KLIMARECHENZENTRUM GMBH - EUROPEAN CENTRE FOR MEDIUM-RANGE WEATHER FORECASTS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - CENTRE EUROPEEN DE RECHERCHE ET DE FORMATION AVANCEE EN CALCUL SCIENTIFIQUE - BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION - SCIENCE AND TECHNOLOGY FACILITIES COUNCIL - MET OFFICE - THE UNIVERSITY OF READING - SVERIGES METEOROLOGISKA OCH HYDROLOGISKA INSTITUT - NATIONAL UNIVERSITY OF IRELAND GALWAY - FONDAZIONE CENTRO EURO-MEDITERRANEO SUI CAMBIAMENTI CLIMATICI - DEUTSCHER WETTERDIENST - SEAGATE SYSTEMS UK LIMITED - BULL SAS - ALLINEA SOFTWARE LIMITED - - - EUR 4 951 048,75 - - - Excellence in SImulation of Weather and Climate in Europe - - - EUR 4 951 048,75 - - - Germany - United Kingdom - France - Germany - France - Spain - United Kingdom - United Kingdom - United Kingdom - Sweden - Ireland - Italy - Germany - United Kingdom - France - United Kingdom - - - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - ESiWACE will substantially improve efficiency and productivity of numerical weather and climate simulation on high-performance computing platforms by supporting the end-to-end workflow of global Earth system modelling in HPC - environment. This will be obtained by improving and supporting (1) scalability of models, tools and data management on state-of-the-art supercomputer systems (2) Usability of models and tools throughout the European HPC eco-system, and (3) the - Exploitability of the huge amount of resulting data. - - 2019-08-31, ongoing project | - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.3."> - - - EINFRA-5-2015 - Centres of Excellence for computing applications - - - RIA - Research and Innovation action - - - Germany - - - ESiWACE - - - H2020-EINFRA-2015-1 - - - 675191 - - - - - CONSIGLIO NAZIONALE DELLE RICERCHE - Koninklijk Instituut voor het Kunstpatrimonium - Doerner Institut, Bayerische Staatsgemäldesammlungen - STIFTUNG PREUSSISCHER KULTURBESITZ - RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN - STATENS MUSEUM FOR KUNST - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - Museo Nacional del Prado - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE - Société civile SYNCHROTRON SOLEIL - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - IDRYMA ORMYLIA - Magyar Tudomanyos Akademia Atommagkutato Intezete - MAGYAR TUDOMANYOS AKADEMIA WIGNER FIZIKAI KUTATOKOZPONT - AGENZIA PER LA PROMOZIONE DELLA RICERCA EUROPEA - OPIFICIO DELLE PIETRE DURE - ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA - MINISTERIE VAN ONDERWIJS, CULTUUR EN WETENSCHAP - UNIWERSYTET MIKOLAJA KOPERNIKA W TORUNIU - LABORATORIO NACIONAL DE ENGENHARIA CIVIL - BRITISH MUSEUM - THE NATIONAL GALLERY - THE J. PAUL GETTY TRUST - - - EUR 7 994 987,73 - - - Integrated Platform for the European Research Infrastructure ON Cultural Heritage - - - EUR 8 157 487,73 - - - Italy - Belgium - Germany - Germany - Germany - Denmark - Spain - Spain - France - France - France - Greece - Greece - Hungary - Hungary - Italy - Italy - Italy - Netherlands - Poland - Portugal - United Kingdom - United Kingdom - United States - - - Research Organisations - Research Organisations - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Other - - IPERION CH aims to establish the unique pan-European research infrastructure in Heritage Science by integrating national world-class facilities at research centres, universities and museums. The cross-disciplinary consortium - of 23 partners (from 12 Member States and the US) offers access to instruments, methodologies and data for advancing knowledge and innovation in the conservation and restoration of cultural heritage. Fourth in a line of successful projects - (CHARISMA-FP7, Eu-ARTECH-FP6 and LabS-TECH network-FP5), IPERION CH widens trans-national access by adding new providers with new expertise and instruments to the three existing complementary platforms ARCHLAB, FIXLAB and MOLAB. - - - 2019-04-30, ongoing project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.2."> - - - INFRAIA-1-2014-2015 - Integrating and opening existing national and regional research infrastructures of European interest - - - RIA - Research and Innovation action - - - Italy - - - IPERION CH - - - H2020-INFRAIA-2014-2015 - - - 654028 - - - - - FORSCHUNGSZENTRUM JULICH GMBH - Gauss Centre for Supercomputing (GCS) e.V. - GRAND EQUIPEMENT NATIONAL DE CALCUL INTENSIF - THE UNIVERSITY OF EDINBURGH - BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION - CSC-TIETEEN TIETOTEKNIIKAN KESKUS OY - Eidgenössische Technische Hochschule Zürich - SURFSARA BV - UNIVERSITAT LINZ - UPPSALA UNIVERSITET - CINECA CONSORZIO INTERUNIVERSITARIO - INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK - UNINETT SIGMA2 AS - ETHNIKO DIKTYO EREVNAS TECHNOLOGIAS AE - UNIVERSIDADE DE COIMBRA - NATIONAL UNIVERSITY OF IRELAND GALWAY - ISTANBUL TEKNIK UNIVERSITESI - THE CYPRUS RESEARCH AND EDUCATIONAL FOUNDATION - "ASSOCIATION ""NATIONAL CENTRE FOR SUPERCOMPUTING APPLICATIONS" - VYSOKA SKOLA BANSKA - TECHNICKA UNIVERZITA OSTRAVA - NEMZETI INFORMACIOS INFRASTRUKTURA FEJLESZTESI IRODA - KORMANYZATI INFORMATIKAI FEJLESZTESI UGYNOKSEG - KOBENHAVNS UNIVERSITET - MACHBA - INTERUNIVERSITY COMPUTATION CENTER - PARTNERSHIP FOR ADVANCED COMPUTINGIN EUROPE AISBL - UNIVERZA V LJUBLJANI - VYPOCTOVE STREDISKO SLOVENSKEJ AKADEMIE VIED - - - EUR 15 000 000 - - - PRACE 4th Implementation Phase Project - - - EUR 16 354 408,25 - - - Germany - Germany - France - United Kingdom - Spain - Finland - Switzerland - Netherlands - Austria - Sweden - Italy - Poland - Norway - Greece - Portugal - Ireland - Turkey - Cyprus - Bulgaria - Czech Republic - Hungary - Hungary - Denmark - Israel - Belgium - Slovenia - Slovakia - - - Research Organisations - Research Organisations - Other - Higher or Secondary Education Establishments - Research Organisations - Other - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Other - Higher or Secondary Education Establishments - Research Organisations - - PRACE, the Partnership for Advanced Computing, was established in May 2010 as a permanent pan-European High Performance Computing service providing world-class systems for world-class science. Six systems at the highest - performance level (Tier-0) are deployed by Germany, France, Italy and Spain providing researchers with over 9 billion core hours of compute time. HPC experts from twenty-five member states - funded in part in three implementation projects - enabled - users from academia and industry to ascertain leadership and remain competitive in the Global Race. Currently PRACE is preparing for PRACE 2.0, the successor of the initial five year period. - - - 2017-12-31, closed project - - - 2015-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.3."> - - - EINFRA-4-2014 - Pan-European High Performance Computing infrastructure and services - - - RIA - Research and Innovation action - - - Germany - - - PRACE-4IP - - - H2020-EINFRA-2014-2 - - - 653838 - - - - - UNIVERSITAET ZU KOELN - - - EUR 2 354 400 - - - a.r.t.e.s. EUmanities - European Graduate School for the Humanities Cologne - - - EUR 4 708 800 - - - Germany - - - Higher or Secondary Education Establishments - - artes EUmanities offers a doctoral programme (DP) with a mandatory mobility phase, as part of the established artes Graduate School for the Humanities Cologne (AGSHC). Designed around the needs of each individual Early Stage - Researcher (ESR) in the Humanities, it will provide places for up to 10 ESRs every year for 3 years. - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2015-DP - Marie Skłodowska-Curie Co-funding of regional, national and international programmes (COFUND-DP) - - - MSCA-COFUND-DP - Doctoral programmes - - - Germany - - - artes EUmanities - - - H2020-MSCA-COFUND-2015 - - - 713600 - - - - - UNIVERSITEIT UTRECHT - EUROPEAN MOLECULAR BIOLOGY LABORATORY - DIAMOND LIGHT SOURCE LIMITED - CONSORZIO INTERUNIVERSITARIO RISONANZE MAGNETICHE DI METALLO PROTEINE - JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN - STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS - Masarykova univerzita - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - FORSCHUNGSVERBUND BERLIN EV - Société civile SYNCHROTRON SOLEIL - LUNDS UNIVERSITET - UNIVERSITEIT LEIDEN - ACADEMISCH ZIEKENHUIS LEIDEN - INSTALLATION EUROPEENNE DE RAYONNEMENT SYNCHROTRON - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - INSTRUCT ACADEMIC SERVICES LIMITED - AARHUS UNIVERSITET - EUROPEAN SPALLATION SOURCE ERIC - EUROPEAN SPALLATION SOURCE ESS AB - EOTVOS LORAND TUDOMANYEGYETEM - UNIVERSIDADE NOVA DE LISBOA - INSTITUTO DE TECNOLOGIA QUIMICA E BIOLOGICA - UNIVERSIDADE NOVA DE LISBOA - OULUN YLIOPISTO - PANEPISTIMIO PATRON - WEIZMANN INSTITUTE OF SCIENCE - - - EUR 9 999 534,25 - - - Infrastructure for NMR, EM and X-rays for translational research - - - EUR 9 999 534,25 - - - Netherlands - Germany - United Kingdom - Italy - Germany - Netherlands - Czech Republic - Spain - Germany - France - Sweden - Netherlands - Netherlands - France - France - United Kingdom - Denmark - Sweden - Sweden - Hungary - Portugal - Portugal - Finland - Greece - Israel - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Other - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Structural biology provides insight into the molecular architecture of cells up to atomic resolution, revealing the biological mechanisms that are fundamental to life. It is thus key to many innovations in chemistry, - biotechnology and medicine such as engineered enzymes, new potent drugs, innovative vaccines and novel biomaterials. - - 2019-08-31, ongoing project | - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.2."> - - - INFRAIA-1-2014-2015 - Integrating and opening existing national and regional research infrastructures of European interest - - - RIA - Research and Innovation action - - - Netherlands - - - iNEXT - - - H2020-INFRAIA-2014-2015 - - - 653706 - - - - - INSTITUT MAX VON LAUE - PAUL LANGEVIN - EUROPEAN SPALLATION SOURCE ESS AB - EUROPEAN SPALLATION SOURCE ERIC - SCIENCE AND TECHNOLOGY FACILITIES COUNCIL - PAUL SCHERRER INSTITUT - TECHNISCHE UNIVERSITAET MUENCHEN - FORSCHUNGSZENTRUM JULICH GMBH - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - TECHNISCHE UNIVERSITEIT DELFT - HELMHOLTZ-ZENTRUM BERLIN FUR MATERIALIEN UND ENERGIE GMBH - HELMHOLTZ-ZENTRUM GEESTHACHT ZENTRUM FUR MATERIAL- UND KUSTENFORSCHUNG GMBH - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - KOBENHAVNS UNIVERSITET - DANMARKS TEKNISKE UNIVERSITET - NUCLEAR PHYSICS INSTITUTE OF THE ASCR VVI - CONSORCIO PARA LA CONSTRUCCION, EQUIPAMIENTO Y EXPLOTACION DE LA SEDE ESPANOLA DE LA FUENTE EUROPEA DE NEUTRONES POR ESPALACION - MAGYAR TUDOMANYOS AKADEMIA ENERGIATUDOMANYI KUTATOKOZPONT - LABORATORIO DE INSTRUMENTACAO E FISICA EXPERIMENTAL DE PARTICULAS - UNIVERSITA DEGLI STUDI DI PARMA - - - EUR 10 863 447 - - - World class Science and Innovation with Neutrons in Europe 2020 – SINE2020 - - - EUR 12 080 866,25 - - - France - Sweden - Sweden - United Kingdom - Switzerland - Germany - Germany - France - Netherlands - Germany - Germany - Spain - Denmark - Denmark - Czech Republic - Spain - Hungary - Portugal - Italy - - - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - - Today’s society is being transformed by new materials and processes. Analytical techniques underpin their development and neutrons, with their unique properties, play a pivotal role in a multi-disciplinary, knowledge-based - approach. Industry and the neutron research community must however work together more closely to enhance their innovation potential. - - 2019-09-30, ongoing project | - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-4-2014-2015 - Implementation and operation of cross-cutting services and solutions for clusters of ESFRI and other relevant research infrastructure initiatives - - - RIA - Research and Innovation action - - - France - - - SINE2020 - - - H2020-INFRADEV-1-2014-1 - - - 654000 - - - - - UNIVERSITAET POTSDAM - THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN - LANCASTER UNIVERSITY - UNIVERSITA DEGLI STUDI DI FIRENZE - UNIVERSIDAD POMPEU FABRA - STICHTING VU - FAKULTETA ZA INFORMACIJSKE STUDIJE V NOVEM MESTU - MEDIZINISCHE UNIVERSITAT GRAZ - - - EUR 3 878 421,12 - - - Complex Oscillatory Systems: Modeling and Analysis - - - EUR 3 878 421,12 - - - Germany - United Kingdom - United Kingdom - Italy - Spain - Netherlands - Slovenia - Austria - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Many natural and artificial systems are often composed of oscillatory elements which, besides evolving according to their own non-trivial internal dynamics, mutually interact. As a result, many temporal and spatial scales are - typically present, often accompanied by the spontaneous emergence of collective properties. Altogether, such features make the task of understanding the resulting evolution a challenging interdisciplinary problem. Zero-knowledge methods do generally - require too large amount of data to allow drawing meaningful conclusions. In order to overcome this limitation, it is necessary to add skilful hypotheses about the structure of the underlying model and, thereby, on the relevant variables. This task - is often tackled in an ad hoc way and the approach is based rather on personal preferences than on objective elements. The goal of this project is to fill the gap, by developing a general and coherent set of tools for the system identification and - control, as well as to improve our ability to make predictions. The task will be pursued by combining top-down with bottom-up approaches which will be used to identify the most appropriate variables. Such analysis will be integrated by performing - suitable case studies and mutually validating the various techniques to test the correctness of the underlying assumptions (both in the context of theoretical models as well as in experimental time series, such as physiological and neural data). A - user-friendly software package will be ultimately developed to make the methods accessible to a broad set of potential users, including those with minimal theoretical competences. Furthermore, we will train a new generation of scientists able to - implement a broad range of interdisciplinary approaches to the multivariate time signals that may be generated by the evolution of complex systems. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-EJD - Marie Skłodowska-Curie Innovative Training Networks (ITN-EJD) - - - MSCA-ITN-EJD - European Joint Doctorates - - - Germany - - - COSMOS - - - H2020-MSCA-ITN-2014 - - - 642563 - - - - - MALOPOLSKA VOIVODSHIP - AKADEMIA GORNICZO-HUTNICZA IM. STANISLAWA STASZICA W KRAKOWIE - Akademia Sztuk Pieknych im Jana Matejki w Krakowie - THE HENRYK NIEWODNICZANSKI INSTITUTE OF NUCLEAR PHYSICS, POLISH ACADEMY OF SCIENCES - POLITECHNIKA KRAKOWSKA - UNIWERSYTET JAGIELLONSKI - UNIWERSYTET ROLNICZY IM. HUGONA KOLLATAJA W KRAKOWIE - INSTYTUT NAUK GEOLOGICZNYCH POLSKIEJ AKADEMII NAUK - UNIWERSYTET EKONOMICZNY W KRAKOWIE - KRAKOWSKI SZPITAL SPECJALISTYCZNY IM. JANA PAWLA II - UNIWERSYTET PEDAGOGICZNY IM KOMISJI EDUKACJI NARODOWEJ W KRAKOWIE - PANSTWOWA WYZSZA SZKOLA ZAWODOWA W TARNOWIE - PANSTWOWA WYZSZA SZKOLA ZAWODOWA WNOWYM SACZU - - - EUR 354 506 - - - Malopolska Researchers' Night 2014-2015 - - - EUR 443 723,50 - - - Poland - Poland - Poland - Poland - Poland - Poland - Poland - Poland - Poland - Poland - Poland - Poland - Poland - - - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The project Malopolska Researchers' Night will be implemented in the years 2014 and 2015 respectively for the eighth and ninth time. The event has already permanently inscribed in the calendar of Malopolska scientific events, - enjoying growing from year to year popular among participants and becoming one of the biggest Nights in Europe. In 2013, this event was attended by over 55 thousand people, while in the first year of the project (2007) the event was attended only by - 3.5 thousand people. The event program specified in the application is even richer than before – it will take over 1 thousand activities, mainly interactive workshops, presentations, demonstrations and experiments as well as shows with the - participation of scientists. It is estimated that 60 thousand people will participate in the events in 2014 and 65 thousand people in 2015. Malopolska Researchers' Night is to first of all show participants how interesting is the work of scientists - and how fascinating they are people. Through fun, in accessible and understandable way for everybody, we want to show that all around us is the science, and that scientists in their laboratories are working every day to make our life better, easier - and more modern. The main motto of the project for the years 2014 and 2015 will be to present the successes of Malopolska scientists working in international scientific-research teams. The event will be held in six cities of the Region: Krakow, - Tarnow, Nowy Sacz and Niepolomice and - for the first time in 2014 - also in Skawina and Andrychow. In addition, it is planned the live broadcast from selected locations via event website. The program will be prepared by almost 900 researchers, more - than 1 600 students, about 120 research groups from more than 30 partners. Thanks to the extensive promotional campaign the information about the event will reach to nearly 3.5 million people each year. - - 2015-12-31, closed project - - - 2014-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.5."> - - - MSCA-NIGHT-2014 - European Researchers' Night (NIGHT) - - - CSA - Coordination and support action - - - Poland - - - Power2Nights - - - H2020-MSCA-NIGHT-2014 - - - 633330 - - - - - VEREIN EURESEARCH - Ministerio de Ciencia, Tecnología e Innovación Productiva - BULGARIAN ACADEMY OF SCIENCES - AGENCIJA ZA MOBILNOST I PROGRAME EUROPSKE UNIJE - IDRYMA PROOTHISIS EREVNAS - ACADEMY OF SCIENTIFIC RESEARCH AND TECHNOLOGY ASRT - SIHTASUTUS EESTI TEADUSAGENTUUR - ETHNIKO IDRYMA EREVNON - RANNSOKNAMIDSTOD ISLANDS - AGENZIA PER LA PROMOZIONE DELLA RICERCA EUROPEA - IRISH UNIVERSITIES ASSOCIATION - MATIMOP - THE ISRAELI CENTER FOR R&D - INSTYTUT PODSTAWOWYCH PROBLEMOW TECHNIKI POLSKIEJ AKADEMII NAUK - UNIVERSITATEA DE STIINTE AGRICOLE SI MEDICINA VETERINARA A BANATULUI REGELE MIHAI I AL ROMANIEI DIN TIMISOARA - TURKIYE BILIMSEL VE TEKNOLOJIK ARASTIRMA KURUMU - - - EUR 1 498 353 - - - Net4Mobility: Network of the Marie Skłodowska-Curie Actions National Contact Points - - - EUR 1 777 949,25 - - - Switzerland - Argentina - Bulgaria - Croatia - Cyprus - Egypt - Estonia - Greece - Iceland - Italy - Ireland - Israel - Poland - Romania - Turkey - - - Other - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Other - Higher or Secondary Education Establishments - Other - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - - The objective of the Net4Mobility project is to facilitate the transnational cooperation between the National Contact Points (NCPs) of the Marie Sklodowska-Curie Actions (MSCA). The project aims to achieve the following two - goals: 1) mutual support and thus raising the general standard of applicants (taking into account the diversity of the different actors) 2) to better inform the research and innovation stakeholders on funding possibilities in the MSCA and help them - to improve their performance. Thus, ultimately our goal is to support research and innovation. As a synergy effect, the work processes of REA, EC and NCPs will be optimized and more effective. - - - 2018-01-31, closed project - - - 2015-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.5."> - - - MSCA-NCP-2014 - Trans-national cooperation among Marie Skłodowska-Curie National Contact Points (NCP) - - - CSA - Coordination and support action - - - Switzerland - - - Net4Mobility - - - H2020-MSCA-NCP-2014 - - - 640603 - - - - - UNIVERSITY COLLEGE LONDON - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA - UNIVERSITA DI PISA - Surflay Nanotec GmbH - BAYERISCHE JULIUS-MAXIMILIANS UNIVERSITAT WURZBURG - GESELLSCHAFT FUR ANGEWANDTE MIKRO UND OPTOELEKTRONIK MIT BESCHRANKTERHAFTUNG AMO GMBH - UNIVERSITA DEGLI STUDI DI GENOVA - UNIVERSITE DE STRASBOURG - UNIVERSITY OF CYPRUS - - - EUR 3 650 589 - - - SupramolecularlY eNgineered arCHitectures for optoelectRonics and photONICS: a multi-site initial training action - - - EUR 3 650 589 - - - United Kingdom - United Kingdom - Italy - Italy - Germany - Germany - Germany - Italy - France - Cyprus - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Chiara Andreoli - Tel.: +3901071781854 - Fax: +39 010 7170817 - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Other - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Photonics will play a major, enabling role in the future of ICT and healthcare. However, to fulfill its potential and deliver on its promises, photonics will heavily rely on novel and more performing materials, that can be - manufactured cheaply for the specific requirements of photonic applications. To lead this “photonics revolution” and rip the societal benefits of being at the leading-edge of novel technological and scientific developments, the EC needs a - highly-skilled scientific and technical workforce that can effectively implement the transition to a truly “knowledge-based society”. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - SYNCHRONICS - - - H2020-MSCA-ITN-2014 - - - 643238 - - - - - FONDATION EUROPEENNE DE LA SCIENCE - AGENZIA PER LA PROMOZIONE DELLA RICERCA EUROPEA - ETHNIKO IDRYMA EREVNON - - - EUR 1 951 092 - - - MERIL-2 MAPPING OF THE EUROPEAN RESEARCH INFRASTRUCTURE LANDSCAPE - - - EUR 1 951 092 - - - France - Italy - Greece - - - Other - Research Organisations - Research Organisations - - The MERIL-2 project aims to create an authoritative, exhaustive online source of scientific and policy relevant data on European research infrastructures (RIs) of more than national relevance. It addresses the work programme - priorities of promoting the development and coordination of policy and international cooperation in the domain of RIs. MERIL-2 builds on the successful development of the original MERIL and research mapping exercise initiated by the ESF membership - and which services ESFRI. MERIL-2 aims to achieve step changes in terms of: 1) The comprehensiveness of RIs identified in the portal from 900 to 1200+ and the full publication of those identified from 500 to 800; 2) The utility of the portal in terms - of functionalities, analytical capacity and intermediation; 3) Stakeholder value in terms of policy relevant data including financial and human resource dimensions and coverage of RI mapping processes and tools in comparator regions. These objectives - will be met through a synergistic partnership of three organisations; European Science Foundation (ESF), the Greek National Documentation Centre (EKT-NHRF) and Agency for the Promotion of Research (APRE), that harnesses the complementary strengths of - advanced portal design, European member state communication systems and deep knowledge of the RI landscape and data acquisition requirements under the leadership of an expert advisory committee. On a practical level, the approach will include - redesign of the portal with enhanced functionalities, expert/ESFRI and NDI consultations on policy data needs and parameters, a complementary review of RI data policies and strategies and policies including implications of policy data provision and - resourcing a publishing completion function for non-responsive RIs. These actions will lead to an enhanced MERIL-2 portal with comprehensive coverage of the European RI landscape and high quality systems and data of stakeholder interest with - flexible, open and user oriented interfaces. - - 2019-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.3.1."> - - - INFRASUPP-5-2014 - Policy measures for research infrastructures - - - CSA - Coordination and support action - - - France - - - MERIL-2 - - - H2020-INFRASUPP-2014-2 - - - 654296 - - - - - THE UNIVERSITY OF BIRMINGHAM - - - EUR 195 454,80 - - - Comprehensive code for stellar dating, and analysis of exoplanetary systems observed by direct imaging - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - THOT is an ambitious project for delivering estimated ages for large numbers of stars in the Galaxy. The main aims of THOT are: 1) To gather all the techniques for stellar dating, 2) to update those having the most potential - for application to data from new and upcoming missions, 3) to develop a code to automate stellar dating and, 4) to apply this code to study exoplanetary systems observed by direct imaging. This ambitious programme will be delivered at the University - of Birmingham (UoB) by Dr. Moya, supervised by Prof. William Chaplin in close collaboration with Drs. A. Miglio and G. Davies. A two-year plan including working packages, deliverables, milestones, and training objectives is presented, showing the - feasibility and innovation of the project. THOT has three secondments planned at different academic institutes: 1) CAB – INTA/CSIC, Spain, Dr. David Barrado, 2) IA, Portugal, Dr. Elisa Delgado, and 3) UNED, Spain, Dr. Luis Manuel Sarro. These - secondments complement the needed skills for the project and open key collaboration lines for THOT and for the long-term project for which THOT is the first step: an EU collaboration network for stellar dating and the development of a “map of ages” - to understand how the region of the Galaxy around our Sun evolves. Because of his career, Dr. Moya will be able to make the most of this fellowship opportunity. The Solar and Stellar group, led by Prof. Chaplin at UoB, is the best option for him to - deliver success. The proven leadership and independent thinking of Dr. Moya, together with the new opportunities and skills that the UoB research group offers, will provide a major boost to Dr. Moya’s scientific career. A complete plan for - dissemination, exploitation and communication of the results is also presented. The UoB is committed to the successful outcome of THOT. UoB and the institutes that will host the secondments all have proven track records of successfully hosting Marie - Curie fellows as outlined in Part B section 5. - - 2019-10-15, ongoing project - - - 2017-10-16 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - United Kingdom - - - THOT - - - H2020-MSCA-IF-2016 - - - 749962 - - - - - UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6 - NACIONALNI INSTITUT ZA BIOLOGIJO - STICHTING NIOZ, KONINKLIJK NEDERLANDS INSTITUUT VOOR ONDERZOEK DER ZEE - HELSINGIN YLIOPISTO - INSTYTUT OCEANOLOGII POLSKIEJ AKADEMII NAUK - UNIWERSYTET GDANSKI - NATIONAL UNIVERSITY OF IRELAND GALWAY - GOETEBORGS UNIVERSITET - UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA - HELLENIC CENTRE FOR MARINE RESEARCH - THE HEBREW UNIVERSITY OF JERUSALEM - STAZIONE ZOOLOGICA ANTON DOHRN - UNIVERSITETET I BERGEN - CENTRO DE CIENCIAS DO MAR DO ALGARVE - ALFRED-WEGENER-INSTITUT HELMHOLTZ-ZENTRUM FUR POLAR- UND MEERESFORSCHUNG - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - VLAAMS INSTITUUT VOOR DE ZEE VZW - THE SCOTTISH ASSOCIATION FOR MARINESCIENCE LBG - THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS - MARINE BIOLOGICAL ASSOCIATION OF THE UNITED KINGDOM - NATURAL ENVIRONMENT RESEARCH COUNCIL - MARINE SCOTLAND - AquaTT UETP Ltd - - - EUR 9 999 911,47 - - - Association of European Marine Biological Laboratories Expanded - - - EUR 9 999 911,48 - - - France - Slovenia - Netherlands - Finland - Poland - Poland - Ireland - Sweden - Spain - Greece - Israel - Italy - Norway - Portugal - Germany - Germany - Belgium - United Kingdom - United Kingdom - United Kingdom - United Kingdom - United Kingdom - Ireland - - - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Other - - Marine biological stations have offered services and biological resources to science for more than a century. ASSEMBLE Plus will provide scientists from academia, industry and policy with a quality-assured programme of - Transnational Access (TA) and Virtual Access (VA) to marine biological stations offering a wide variety of marine ecosystems, unique marine biological resources, state-of-the-art experimental and analytical facilities with integrated workflows, - historical observation data, and advanced training opportunities. The goal is to stimulate European excellence in fundamental and applied research in marine biology and ecology, thereby improving our knowledge- and technology-base for the blue - economy, policy and education. ASSEMBLE Plus brings together 33 marine stations and institutes with modern research infrastructure and track-records of unique service provision from 14 European and associated countries under the leadership of the - European Marine Biological Resource Centre (EMBRC), an ESFRI consortium developed from the previous ASSEMBLE (FP7) partnership. Joint Research Activities involving all partners aim to develop innovative new technologies and/or methodologies to be - offered to users through the TA and VA programmes. A coherent series of Networking Activities (NAs) will strengthen the culture of cooperation within and beyond the consortium, providing benchmarks for refined practices of service provision, - disseminating interoperable protocols, engaging with novel user communities, and sharing insights into business strategies. The sum of the actions envisaged in ASSEMBLE Plus will ultimately increase the number of users of marine biological stations - and shape novel strategic development perspectives, to be based on effective integration and efficient complementarities, resulting in a key contribution to their long-term sustainability. - - 2021-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.2."> - - - INFRAIA-01-2016-2017 - Integrating Activities for Advanced Communities - - - RIA - Research and Innovation action - - - France - - - ASSEMBLE Plus - - - H2020-INFRAIA-2016-1 - - - 730984 - - - - - KOBENHAVNS UNIVERSITET - UNIVERSITE DU LUXEMBOURG - UNIVERSIDAD REY JUAN CARLOS - CARDIFF UNIVERSITY - REGION HOVEDSTADEN - 3SHAPE TRIOS AS - GMV SOLUCIONES GLOBALES INTERNET SAU - SYNOPSYS (NORTHERN EUROPE) LIMITED - AALBORG UNIVERSITET - - - EUR 4 013 444,88 - - - Rapid Biomechanics Simulation for Personalized Clinical Design - - - EUR 4 013 444,88 - - - Denmark - Luxembourg - Spain - United Kingdom - Denmark - Denmark - Spain - United Kingdom - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - Clinical experts make design decisions on treatments, interventions, or on devices. ICT empowers them with patient-specific simulation models that enable better-informed design decisions. But patient-specific computational - medicine is currently cumbersome, slow, and unintuitive; it relies on complex processing by technical experts, and it is hence far from reaching its full potential on clinical design, and scarcely used. - - 2022-03-31, Grant Agreement signed - - - 2018-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Denmark - - - RAINBOW - - - H2020-MSCA-ITN-2017 - - - 764644 - - - - - SABANCI UNIVERSITESI - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - AALBORG UNIVERSITET - - - EUR 418 500 - - - TACTILENet: Towards Agile, effiCient, auTonomous and massIvely LargE Network of things - - - EUR 517 500 - - - Turkey - United Kingdom - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The vision for the 5th generation of mobile networks (5G) includes at its heart the Internet of Things (IoT) paradigm, leading to a new era of connectivity where billions of devices exchange data and instill intelligence in - our everyday life. The EU has set out to play a leading role in developing 5G technologies by consolidating and building upon the most important research and innovation results attained in previous research programs. Nevertheless, 5G is still in its - early research stages. Various issues must be resolved before it can become a reality: we need to join forces – across countries, continents, and sectors. - - 2019-01-31, ongoing project - - - 2016-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Turkey - - - TACTILENet - - - H2020-MSCA-RISE-2015 - - - 690893 - - - - - THE CYPRUS INSTITUTE - UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA - HUMBOLDT-UNIVERSITAET ZU BERLIN - BERGISCHE UNIVERSITAET WUPPERTAL - UNIVERSITY OF CYPRUS - UNIVERSITA DEGLI STUDI DI FERRARA - RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN - THE HEBREW UNIVERSITY OF JERUSALEM - - - EUR 3 755 601 - - - Simulation in multiscale physical and biological systems - - - EUR 3 755 601 - - - Cyprus - Italy - Germany - Germany - Cyprus - Italy - Germany - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Simulation alongside theory and experiment is nowadays considered an integral part of scientific discovery. As computation speeds up and new technologies and instruments improve, data generation in all fields of science is - rapidly increasing. As a consequence, researchers face new challenges: Data collection exceeds by far the capacity to validate, analyze, visualize, store, and curate the information contained. Additionally, traditional, single-scale, macroscopic - physical models are becoming inadequate for the accuracy requirements of modern physical, biological and engineering applications that involve multiscale phenomena occurring over vastly different scales. Tackling these challenges will transform our - approach to research potentially leading to unprecedented data-driven scientific discoveries. The overall goal of STIMULATE is to deliver an innovative interdisciplinary educational and research program in simulation and data science, which educates - students to best address the challenges posed by exascale computing and intensive data applications, producing computational science professionals tactically positioned to become leaders in both academia and industry. The project proposes a rigorous - network-wide training program and research projects that combine mathematical modeling and algorithms for exascale simulations and data-intensive science with applications in the fields of Computational Fluid Dynamics, Computational Biology and - Particle and Nuclear Physics with focus in lattice Quantum Chromodynamics. Students will be seconded to industrial partners that will complement expertise in computer technologies, mathematical modeling and data analytics with hands-on training. - Experts from eight degree-awarding institutions, three research centers and three companies are engaged in the project. Each of the fifteen fellows of the program will obtain a single joint Ph.D. degree from three academic institutions. - - 2022-05-31, Grant Agreement signed - - - 2018-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-EJD - European Joint Doctorates - - - Cyprus - - - STIMULATE - - - H2020-MSCA-ITN-2017 - - - 765048 - - - - - ACADEMISCH ZIEKENHUIS GRONINGEN - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - THE UNIVERSITY OF NOTTINGHAM - UNIVERSITATSKLINIKUM ERLANGEN - CHARITE - UNIVERSITAETSMEDIZIN BERLIN - OTICON A/S - WIDEX AS - COCHLEAR RESEARCH AND DEVELOPMENT LIMITED - - - EUR 3 928 915,08 - - - Research School for TINnitus Assessment, Causes and Treatments - - - EUR 3 928 915,08 - - - Netherlands - France - United Kingdom - Germany - Germany - Denmark - Denmark - United Kingdom - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Tinnitus (“ringing in the ears”) is a very common and potentially devastating condition. People with tinnitus, continuously hear a penetrating phantom sound in absence of actual sound. An estimated 50.8 million EU citizens - hear tinnitus, of which 5.1 million are severely bothered by it. Tinnitus can totally disrupt normal societal participation. Hence, tinnitus leads to enormous societal costs (€140 billion per year in Europa), mainly due to loss of productivity. Since - tinnitus primary occurs at advanced age (>50 years), it is a severe challenge to the European ambition to continued inclusion of the aging population in the work force. To date, the research into tinnitus has progressed almost nowhere in the - development of effective and reliable treatments for tinnitus. The applicants of the current proposal are convinced that in order to cure tinnitus, we need researchers that can bridge the gap between basic fundamental research, applied clinical - research and product development. The major aim of the proposal is to train 15 future scientists who understand how basic neural mechanisms of tinnitus can be studied in animal models and human tinnitus patients, and how complementary research - techniques can be used towards curing tinnitus. The central hypothesis of TIN-ACT is that reduced peripheral auditory input (via hearing loss) causes pathological changes centrally in the brain that manifest as the perception of tinnitus. In a - balanced consortium, the research is organized in three scientific work packages that study how these pathological changes can be assessed, what causes them, and how they can be treated. A comprehensive training program provides specialized training - by research, complementary skills and soft skills (including entrepreneurship). We will train 15 early stage researchers (ESRs) towards an excellent understanding of tinnitus assessment, causes and treatments, and with job perspectives both in the - academic and non-academic sectors. - - 2021-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Netherlands - - - TIN-ACT - - - H2020-MSCA-ITN-2017 - - - 764604 - - - - - UNIVERSITETET I OSLO - STICHTING NATURALIS BIODIVERSITY CENTER - GOETEBORGS UNIVERSITET - KOBENHAVNS UNIVERSITET - ROYAL BOTANIC GARDENS KEW - ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS - AGENTSCHAP PLANTENTUIN MEISE - BASECLEAR BV - ROYAL BOTANIC GARDEN EDINBURGH - - - EUR 4 062 035,52 - - - Molecular Identification of Plants - - - EUR 4 062 035,52 - - - Norway - Netherlands - Sweden - Denmark - United Kingdom - Greece - Belgium - Netherlands - United Kingdom - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - - Many of the nearly 400,000 species of plants provide food, feed, medicines, and construction materials. Besides these positive impacts, plants also affect us negatively through pollen allergies, poisonous species, as invasive - species, and as adulterants in herbal medicines. Nevertheless, plants are the most promising biological resource for our future. Current extinction risks of global flora and vast decline in taxonomic expertise demand accurate and rapid identification - approaches to understand and valorise botanical biodiversity. Advances in genomic data and DNA sequencing are revolutionizing plant systematics, and modern molecular identification methods make it possible to accurately determine plants in ways that - were technically impossible only a decade ago. Recently, it has become possible to detect substitution in herbal pharmaceuticals, monitor invasive alien species, trace fragments such as pollen and spores, uncover illegal trade in endangered species, - make rapid and accurate molecular biodiversity assessments, and study historical plant diversity through DNA in museum specimens. However, to efficiently harvest the potential of the opportunities provided by the new genomic techniques, society today - is in urgent need of trained biosystematists experienced in both taxonomy and in handling enormous amounts of genomic data. Plant.ID will innovatively address these challenges by bringing together academic and non-academic partners including - regulatory agencies, industry, SMEs and NGO stakeholders, with the aim of developing molecular identification of plants through tailored approaches to species delimitation, metabarcoding, gene capture, and genomic barcoding, in order to empower - stakeholders with simplified molecular identification of plants. By bridging classical taxonomic expertise with cutting-edge genomic approaches, Plant.ID will train a new generation of ESRs who will have immediate relevance to harnessing the central - role of plants in the modern world. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Norway - - - Plant.ID - - - H2020-MSCA-ITN-2017 - - - 765000 - - - - - FUNDACIO PRIVADA INSTITUT CATALA D'INVESTIGACIO QUIMICA - UNIVERSITE DE NEUCHATEL - FREIE UNIVERSITAET BERLIN - THE UNIVERSITY OF WARWICK - CONSIGLIO NAZIONALE DELLE RICERCHE - INSTITUTE OF ORGANIC CHEMISTRY - POLISH ACADEMY OF SCIENCES - UNIVERSITE DE STRASBOURG - MIND THE BYTE SL - COVESTRO DEUTSCHLAND AG - - - EUR 2 525 640,84 - - - Network of Functional Molecular Containers with Controlled Switchable Abilities - - - EUR 2 525 640,84 - - - Spain - Switzerland - Germany - United Kingdom - Italy - Poland - France - Spain - Germany - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - NOAH deals with the education of early-stage researchers (ESRs) in a multidisciplinary chemical research program within the area of functional molecular containers, encapsulation processes and their applications with the - possibility to end up with a PhD degree. The proposed training network aims to bring in a great variety of scientific attributes to 10 selected ESRs, ranging from the experimental organic and inorganic synthesis to computational chemistry. Photo- and - electro-chemistry, MS/gas-phase chemistry, X-ray diffraction and optical spectroscopy techniques will be also included in the scientific formation and development of the recruited ESRs. The trainees will also receive education in complementary and - transferable skills through attendance to local and network-wide dedicated training seminars (e.g. dissemination, communication, organization, governance, ethics…). The training program includes the exposure of the ESRs to chemical research carried - out in the non-academic sector or in a technological centre by means of full recruitment or short stage secondments in one of the three chemical European companies or the technological centre operating at very different levels: one large company, - Covestro, two SMEs, Mind the Byte and Biolitec and one technological centre Leitat. ESRs will also gain insight in the transfer process of knowledge from academia to industry and other complementary soft-skills. The proposed ETN constitutes an ideal - framework to acquaint ESRs, in a modest amount of time (3 years), with a great variety of scientific skills, experimental techniques, soft-skills and technologies. Ten ESRs will be incorporated in a multidisciplinary team formed by 7 research groups - of multiple nationalities that are focused on a common goal and with high involvement of 3 non-academic partners and one technological centre. All PIs are internationally recognized scientists and the scholar scientists have wide experience as tutors - and mentors of ESRs. - - 2022-03-31, Grant Agreement signed - - - 2018-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Spain - - - NOAH - - - H2020-MSCA-ITN-2017 - - - 765297 - - - - - FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG - CONSIGLIO NAZIONALE DELLE RICERCHE - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - STICHTING CENTRUM VOOR WISKUNDE EN INFORMATICA - COMPAGNIE IBM FRANCE SA - MANAGEMENT, ARTIFICIAL INTELLIGENCE AND OPERATIONS RESEARCH SOCIETA' A RESPONSABILITA' LIMITATA - TECHNISCHE UNIVERSITAT DORTMUND - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA - UNIVERSITAET KLAGENFURT - STICHTING KATHOLIEKE UNIVERSITEIT BRABANT - UNIVERSITAET ZU KOELN - - - EUR 3 063 483,72 - - - Mixed-Integer Non-Linear Optimisation Applications - - - EUR 3 063 483,72 - - - Germany - Italy - France - Netherlands - France - Italy - Germany - Germany - Italy - Austria - Netherlands - Germany - - - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Building upon the achievements of the Marie-Curie ITN Mixed-Integer Non-Linear Optimization (MINO) (2012 - 2016), the goal of the Mixed-Integer Non-Linear Optimisation Applications (MINOA) proposal is to train the next - generation of highly qualified researchers and managers in applied mathematics, operations research and computer science that are able to face the modern imperative challenges of European and international relevance in areas such as energy, - logistics, engineering, natural sciences, and data analytics. Twelve Early-Stage Researchers (ESRs) will be trained through an innovative training programme based on individual research projects motivated by these applications that due to their high - complexity will stimulate new developments in the field. The mathematical challenges can neither be met by using a single optimisation method alone, nor isolated by single academic partners. Instead, MINOA aims at building bridges between different - mathematical methodologies and at creating novel and effective algorithmic enhancements. As special challenges, the ESRs will work on dynamic aspects and optimisation in real time, optimisation under uncertainty, multilevel optimization and - non-commutativity in quantum computing. The ESRs will devise new effective algorithms and computer implementations. They will validate their methods for the applications with respect to metrics that they will define. All ESRs will derive - recommendations, both for optimised MINO applications and for the effectiveness of the novel methodologies. These ESRs belong to a new generation of highly-skilled researchers that will strengthen Europe'e human capital base in R&I in the fast - growing field of mathematical optimisation. The ESR projects will be pursued in joint supervision between experienced practitioners from leading European industries and leading optimisation experts, covering a wide range of scientific fields (from - mathematics to quantum computing and real-world applications). - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - MINOA - - - H2020-MSCA-ITN-2017 - - - 764759 - - - - - UNIVERSITY OF BATH - FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA - UNIVERSITAT JAUME I DE CASTELLON - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - "NATIONAL CENTER FOR SCIENTIFIC RESEARCH ""DEMOKRITOS""" - UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA - BAR ILAN UNIVERSITY - SWANSEA UNIVERSITY - UNIVERSITAT KONSTANZ - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - OXFORD PHOTOVOLTAICS LIMITED - 3GSOLAR PHOTOVOLTAICS LTD - GREATCELL SOLAR UK LIMITED - UAB MODERNIOS E-TECHNOLOGIJOS - SAULE SP ZOO - - - EUR 3 852 446,40 - - - MAking pErovskiteS TRuly explOitable - - - EUR 3 852 446,40 - - - United Kingdom - Italy - Spain - United Kingdom - Greece - Italy - Israel - United Kingdom - Germany - Switzerland - United Kingdom - Israel - United Kingdom - Lithuania - Poland - - - Higher or Secondary Education Establishments - Research Organisations - Chiara Andreoli - Tel.: +3901071781854 - Fax: +39 010 7170817 - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The European Training Network MAESTRO (MAking pErovskiteS TRuly explOitable) will generate new skills, knowledge and innovation in the exploitation of perovskite materials in solar power and efficient lighting through - establishing exploitation paths for perovskite devices in an integrated unitary approach. MAESTRO is an intersectoral and multidisciplinary network of 10 academic and 7 industrial beneficiaries from 8 EU and Associated countries, including 2 - countries in the EU-13. It focusses on perovskite semiconductors, a material shown in the last 4 years to have a major impact on solar power and potentially also in display technology. Our research aims to make perovskite based devices commercially - viable. MAESTRO offers broad skills development and experience of cross sector research to 15 Early Stage Researchers, ESRs. Training is provided in (i) science and technology across physics, chemistry, materials science, electrical engineering, in - two major application areas, solar cells and light emitting diodes, and other uses such as lasers and photodiodes; (ii) exploitation from laboratory to fabrication; (iii) transferable skills of communication, information technology, organization, - planning, teamwork, leadership; (iv) skills needed for innovation, such as understanding markets, product life cycles, business models, return on investment. Gender aspects are addressed through supervisors, mentors and training. The research - undertaken by MAESTRO will teach the ESRs how to deal with complexities and uncertainties, making them very broad and highly adaptable. Their PhDs will position them to be comfortable in both corporate and academic worlds. They will be able to seek - careers that are rewarding professionally and financially, through career paths in self-employment, finance, consultancy, contracting, engineering, computer science, production - - 2021-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - MAESTRO - - - H2020-MSCA-ITN-2017 - - - 764787 - - - - - QUEEN MARY UNIVERSITY OF LONDON - UNIVERSIDAD POMPEU FABRA - INSTITUT MINES-TELECOM - UNIVERSITAT LINZ - SONY EUROPE LIMITED - DOREMIR MUSIC RESEARCH AB - ROLI Ltd - - - EUR 3 937 088,16 - - - New Frontiers in Music Information Processing - - - EUR 3 937 088,16 - - - United Kingdom - Spain - France - Austria - United Kingdom - Sweden - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Music Information Processing (also known as Music Information Research; MIR) involves the use of information processing methodologies to understand and model music, and to develop products and services for creation, - distribution and interaction with music and music-related information. MIR has reached a state of maturity where there are standard methods for most music information processing tasks, but as these have been developed and tested on small datasets, - the methods tend to be neither robust to different musical styles or use contexts, nor scalable to industrial scale datasets. To address this need, and to train a new generation of researchers who are aware of, and can tackle, these challenges, we - bring together leading MIR groups and a wide range of industrial and cultural stakeholders to create a multidisciplinary, transnational and cross-sectoral European Training Network for MIR researchers, in order to contribute to Europe's leading role - in this field of scientific innovation, and accelerate the impact of innovation on European products and industry. - - 2022-03-31, Grant Agreement signed - - - 2018-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - MIP-Frontiers - - - H2020-MSCA-ITN-2017 - - - 765068 - - - - - UNIVERZA V LJUBLJANI - UNIVERSITA DEGLI STUDI DI MILANO - UNIVERSITEIT UTRECHT - UNIVERSITAET BASEL - LUNDS UNIVERSITET - UNIVERSITE GRENOBLE ALPES - - - EUR 3 080 389,68 - - - Multidisciplinary European Joint Doctorate in the Design and Development of Glyco Drugs - - - EUR 3 080 389,68 - - - Slovenia - Italy - Netherlands - Switzerland - Sweden - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The PhD4GlycoDrug consortium has a main goal to offer a European Joint Doctorate educational training network in Glyco-Drug Discovery and Development. The network combines 6 academic partners with long tradition in PhD - training and accredited doctoral studies in Organic Chemistry, Medicinal Chemistry, Structural Biology and Pharmacology/Pharmacy. Non-academic partners, 5 SMEs and a research institute also constitute the consortium to offer intersectoral exposure - and quality training in transferable skills to entrepreneurial ESRs. - - 2021-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-EJD - European Joint Doctorates - - - Slovenia - - - PhD4GlycoDrug - - - H2020-MSCA-ITN-2017 - - - 765581 - - - - - UNIVERSITEIT ANTWERPEN - UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6 - UNIVERSIDAD DE VALLADOLID - LATVIJAS ORGANISKAS SINTEZES INSTITUTS - ITA-SUOMEN YLIOPISTO - KLINIKUM DER UNIVERSITAET ZU KOELN - INSTITUTO DE BIOLOGIA EXPERIMENTAL E TECNOLOGICA - - - EUR 3 002 689,44 - - - Integrated Training in Dry Eye Disease Drug Development (IT-DED3) - - - EUR 3 002 689,44 - - - Belgium - France - Spain - Latvia - Finland - Germany - Portugal - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - The European network for Integrated Training in Dry Eye Disease Drug Development (IT-DED3) aims to deliver multidisciplinary and entrepreneurial researchers trained to develop new therapies for patients suffering from dry eye - diseases (DED). DED is a chronic, multifactorial disease of the ocular surface and is a major and increasing healthcare problem due to its high prevalence and economic burden because of the ageing population and frequent computer/tablet/smartphone - usage. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Belgium - - - IT-DED3 - - - H2020-MSCA-ITN-2017 - - - 765608 - - - - - UNIVERSITEIT ANTWERPEN - ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM - FORSCHUNGSZENTRUM JULICH GMBH - THE UNIVERSITY OF SHEFFIELD - UNIVERSITAIR ZIEKENHUIS ANTWERPEN - SYNTHETIC MR AB (PUBL) - ICOMETRIX NV - MRR SYSTEMS LIMITED - QUANTIB BV - SIEMENS HEALTHCARE - - - EUR 3 874 166,64 - - - Breakthroughs in Quantitative Magnetic resonance ImagiNg for improved DEtection of brainDiseases - - - EUR 3 874 166,64 - - - Belgium - Netherlands - Germany - United Kingdom - Belgium - Sweden - Belgium - United Kingdom - Netherlands - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Magnetic resonance imaging (MRI) is one of the most useful and rapidly growing neuroimaging tools. Unfortunately, signal intensities in conventional MRI images are expressed in relative units that depend on scanner hardware - and acquisition protocols. While this does not hinder visual inspection of anatomy, it hampers quantitative comparison of tissue properties within a scan, between successive scans, and between subjects. In contrast, advanced quantitative MRI (Q-MRI) - methods like MR relaxometry or diffusion MRI do enable absolute quantification of biophysical tissue characteristics. Evidence is growing that Q-MRI techniques detect subtle microscopic damage, enabling more accurate and early diagnosis of - neurodegenerative diseases. However, due to the long scan time required for Q-MRI, causing discomfort for patients and limiting the throughput, Q-MRI methods have not entered clinical practice yet. - - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Belgium - - - B-Q MINDED - - - H2020-MSCA-ITN-2017 - - - 764513 - - - - - UNIVERSITEIT TWENTE - GENERAL ELECTRIC DEUTSCHLAND HOLDING GMBH - TECHNISCHE UNIVERSITAET MUENCHEN - KARLSRUHER INSTITUT FUER TECHNOLOGIE - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - CENTRE EUROPEEN DE RECHERCHE ET DE FORMATION AVANCEE EN CALCUL SCIENTIFIQUE - ASSOCIATION POUR LA RECHERCHE ET LE DEVELOPPEMENT DES METHODES ET PROCESSUS INDUSTRIELS - SAFRAN SA - SAFRAN HELICOPTER ENGINES - ANSYS FRANCE SAS - - - EUR 3 873 159 - - - Machine learning for Advanced Gas turbine Injection SysTems to Enhance combustoR performance. - - - EUR 3 873 159 - - - Netherlands - Germany - Germany - Germany - United Kingdom - France - France - France - France - France - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Air transportation is expected to grow persistently over the next decades. Clean combustion technology for aircraft engines is a key enabler to reduce the impact of this growth on ecosystems and humans’ health. The vision for - European aviation is shaped by the Advisory Council for Aviation Research and Innovation in Europe in the Flight Path 2050 goals, which define stringent regulations on pollutant emissions. To meet these goals, the major engine manufacturers develop - lean premixed combustors operated at very high pressure. This development introduces a large risk for reduced reliability and lifetime of engines: pressure oscillations in the combustor called thermoacoustics. Much research has been dedicated to - study this phenomenon over the last decades with mixed success. Industrial experience shows that the pressure oscillations often surface as late as the full engine has been built and tested. Traditional engineering methods fall short of - predictability during the design of the engines due to a high sensitivity of thermoacoustics with respect to barely known input parameters. Aviation industry encounters currently the fourth industrial revolution: cyber-physical systems analyze and - monitor technical systems and take automated decisions. This industrial revolution is known as “Industry 4.0” in Germany and “Industrial Internet” in the USA. An essential enabler of the fourth industrial revolution is Machine Learning. The ITN - MAGISTER will utilize Machine Learning to predict and understand thermoacoustics in aircraft engine combustors, and lead combustion research a revolutionary new approach in this area. The participation of the major aircraft engine OEMs GE, Rolls - Royce, Safran ensures industrial relevance and outreach of the results. The project will shape early career talents in a network of world leading scientists and industrial partners to work on one of the most severe design issues in aviation - technology in the spirit of the fourth industrial revolution. - - 2021-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Netherlands - - - MAGISTER - - - H2020-MSCA-ITN-2017 - - - 766264 - - - - - NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU - CENTRE EUROPEEN DE RECHERCHE ET DE FORMATION AVANCEE EN CALCUL SCIENTIFIQUE - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - TECHNISCHE UNIVERSITAET MUENCHEN - TECHNISCHE UNIVERSITAET BERLIN - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - Eidgenössische Technische Hochschule Zürich - SAFRAN SA - SAFRAN HELICOPTER ENGINES - ANSALDO ENERGIA SWITZERLAND AG - - - EUR 3 974 482,80 - - - Annular Instabilities and Transient Phenomena in Gas Turbine Combustors - - - EUR 3 974 482,80 - - - Norway - France - France - Germany - Germany - United Kingdom - Switzerland - France - France - Switzerland - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The gas turbine industry is a vital driver of innovation, economic growth, jobs, trade and mobility in the EU in both the aviation and power generation sectors. It is a multi-billion Euro high-technology industry whose future - competitiveness depends on a new generation of creative engineers with multi-disciplinary skills who can accelerate the development of new innovations needed for flexible, efficient power generation and sustainable aviation. - - 2021-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Norway - - - ANNULIGhT - - - H2020-MSCA-ITN-2017 - - - 765998 - - - - - UNIVERSITEIT GENT - HELSINGIN YLIOPISTO - AALTO-KORKEAKOULUSAATIO - UNIVERSITETET I OSLO - Asociacion - Centro de Investigacion Cooperativa en Nanociencias - CIC NANOGUNE - NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO - UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK - INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM - RUHR-UNIVERSITAET BOCHUM - KATHOLIEKE UNIVERSITEIT LEUVEN - - - EUR 3 898 797,84 - - - A European Training Network for Functional Hybrid Coatings by Molecular Layer Deposition - - - EUR 3 898 797,84 - - - Belgium - Finland - Finland - Norway - Spain - Netherlands - Ireland - Belgium - Germany - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - HYCOAT is the first ETN at the intersection of chemistry, physics, materials science and engineering dealing with the synthesis and applications of hybrid coatings grown by molecular layer deposition (MLD). With self-limiting - binary reactions, MLD is the ideal ultra-thin film deposition technique, offering unique advantages for growing uniform, conformal hybrid films providing precise and flexible control over the film thickness and chemical composition at molecular - scale. This new field of MLD is pioneered at nanoscience laboratories across Europe. HYCOAT provides a European approach to facilitate an interdisciplinary and multi-environment (Universities, Research Centers, SMEs & Large industries) platform - for training a new generation of MLD researchers. A coordinated effort of 10 beneficiaries and 16 partner organizations from 7 European countries (Belgium, Finland, Germany, Ireland, Netherlands, Norway and Spain), HYCOAT targets the development of - novel precursor chemistries, processes, characterisation and modelling of MLD and the demonstration of hybrid coatings in four key high impact fields of application relevant for European industries, in packaging, biomedical, electronics and - batteries. Understanding and engineering of hybrid coatings by MLD is essential for its wide range of applications and the interaction with European high-tech industry is ensured through the active participation of 10 industries, 2 university - hospitals and a synchrotron facility. Training will take place through research projects, courses and workshops, with the emphasis on self-directed, hands-on, collaborative learning. This European knowledge alliance with an inter- and - trans-disciplinary mobility and an intense collaboration between the private and public entities is needed to equip the next generation of researchers and extrapolate Europe’s current pioneering role in the science of MLD towards a leadership in - economic and societal impact of innovations enabled by MLD. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Belgium - - - HYCOAT - - - H2020-MSCA-ITN-2017 - - - 765378 - - - - - ETHNIKO IDRYMA EREVNON - HITS GGMBH - UNIVERSITA' DEGLI STUDI DI SIENA - UNIVERSITE DE CAEN NORMANDIE - ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON - TECHNISCHE UNIVERSITAET DRESDEN - AvantiCell Science Ltd - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - THE UNIVERSITY OF SHEFFIELD - STICHTING VU - - - EUR 3 555 758,88 - - - A European training network for the discovery of neurotrophins small molecule mimetics as candidate therapeutic agents for neurodegeneration and neuroinflammation - - - EUR 3 555 758,88 - - - Greece - Germany - Italy - France - Greece - Germany - United Kingdom - Greece - United Kingdom - Netherlands - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Neurodegenerative diseases (ND) like AD, PD, MS and ALS/MND are on the rise in developed societies worldwide. Currently, there exists no cure for any ND, and most of the available drugs fail to tackle ND pathogenesis. - Preclinical studies point to the therapeutic potential of neurotrophins, which have been shown to control a number of aspects of survival, development and function of neurons. However, the poor pharmacokinetic properties of neurotrophins render their - use as drugs prohibitive. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Greece - - - EuroNeurotrophin - - - H2020-MSCA-ITN-2017 - - - 765704 - - - - - UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK - UNIVERSIDADE DO MINHO - UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA - JACOBS UNIVERSITY BREMEN GGMBH - UNIVERSITY OF LEICESTER - INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE - - - EUR 3 094 944,48 - - - Yeast Biotechnology Doctoral Training Programme - - - EUR 3 094 944,48 - - - Ireland - Portugal - Italy - Germany - United Kingdom - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - YEASTDOC is a European Joint Doctoral programme to train researchers for outstanding careers as leaders in the field of yeast biotechnology. Six academic institutions are joined by 7 industry and 2 training partner - organisations to offer an international training programme leading to the award of joint PhD degrees. The interdisciplinary, trans-sectoral research topic takes advantage of recent technological developments to link fundamental research in yeasts - with new applications in the beverage and white biotechnology sectors. 12 Early Stage Researchers will each carry out a 36-month joint PhD project between two academic institutions, spending at least 12 months at each partner university in a - different European country. All projects include an industry co-supervisor from a partner organisation and ESRs have an industry secondment of 4-6 months to gain intersectoral experience. Additional research training is provided via summer schools, - scientific conferences, doctoral seminars and practical workshops. Further training in innovation-related skills will be provided through network-wide courses that include technology transfer management and entrepreneurship. Transferrable skills - training is delivered locally in graduate schools and by network courses in responsible research and innovation, scientific writing, and research leadership. ESRs will disseminate research outcomes in the scientific sector and will participate in - outreach activities to engage targeted public audiences in research. All training will receive ECTS credits and be mutually recognised by all academic partners. A joint governance and ESR monitoring structure, including external experts, will assure - the quality of the training programme. The long-term impact of the EJD will be an accredited, sustainable, inter-institutional doctoral programme that delivers high quality PhD graduates to drive research and innovation to maintain competitiveness in - European biotechnology. - - 2021-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-EJD - European Joint Doctorates - - - Ireland - - - YEASTDOC - - - H2020-MSCA-ITN-2017 - - - 764927 - - - - - THE UNIVERSITY OF SHEFFIELD - UNIVERSITY OF DURHAM - CHALMERS TEKNISKA HOEGSKOLA AB - RANPLAN WIRELESS NETWORK DESIGN LTD - TELEVIC CONFERENCE - GAPWAVES AB - UNIVERSITAT POLITECNICA DE VALENCIA - - - EUR 2 880 995,40 - - - mmWave Communications in the Built Environments - - - EUR 2 880 995,40 - - - United Kingdom - United Kingdom - Sweden - United Kingdom - Belgium - Sweden - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - The foreseen exponential growth of mobile data traffic will not be uniform across geographical areas, but is mainly concentrated in hot spots that are usually located in the built environments (BEs) such as central business - districts, stations, airports, stadiums, dense urban environments, etc. This poses considerable challenges that we believe can be solved by ultra dense deployment of millimetre-wave (mmW) small-cells (SCs) in conjunction with massive multiple-input - multipleoutput (MIMO) in 5G and beyond 5G (B5G) wireless networks. However, there are a number of research challenges that need to be addressed for a successful deployment of 5G/B5G wireless networks: even if the theoretical background of massive - MIMO is by now rather complete, the actual performance characterization and measurements of mmW antenna arrays has not yet been fully addressed at either the component or system level; mmW radio channel measurements have been performed but with - limited time delay resolution, single antennas and over single radio links; and mmW bands have been considered for mobile communications, but the level of detail and diversity of BEs necessary for meaningful mmW SC deployment has not been fully - exploited. Therefore, we propose here a research approach that combines the three disruptive key enabling technologies for 5G/B5G with the aim to answer fundamental questions that are still not well understood. - - - 2021-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-EID - European Industrial Doctorates - - - United Kingdom - - - WAVECOMBE - - - H2020-MSCA-ITN-2017 - - - 766231 - - - - - ERASMUS UNIVERSITEIT ROTTERDAM - INSTITUTE OF DEVELOPMENT STUDIES - UNIVERSITAT PASSAU - FREIE UNIVERSITAET BERLIN - HUMBOLDT-UNIVERSITAET ZU BERLIN - WAGENINGEN UNIVERSITY - UNIVERSITY OF BRIGHTON - SVERIGES LANTBRUKSUNIVERSITET - STICHTING IHE DELFT - FONDAZIONE PANGEA ONLUS - - - EUR 3 872 823,12 - - - Well-being, Ecology, Gender, and cOmmunity - - - EUR 3 872 823,12 - - - Netherlands - United Kingdom - Germany - Germany - Germany - Netherlands - United Kingdom - Sweden - Netherlands - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Other - - WEGO (Well-being, Ecology, Gender and cOmmunity) is a trans-national network aims to develop a shared research and training agenda to educate the next generation of interdisciplinary social-environmental scientists on feminist - political ecology in Europe. WeGO’s research examines gender relations in community organizing from a feminist-informed political ecology (FPE) framework. From an international and interdisciplinary perspective, WEGO looks at gender and power - relations in community responses to the current climate, economic and environmental crises in different socio-ecological contexts. WEGO aims to provide insightful and compelling analysis about the importance of gendered community response to climate, - economic and environmental change as well as more detailed knowledge about what changes are required for greater resilience and sustainability. Gender is understood as a critical variable in shaping resource access and control, interacting with - class, caste, race, culture, and ethnicity to shape processes of ecological change and the prospects of any community for sustainable development. WEGO research will look at resilience and sustainability by examining the gendered role of women in - care work for the community and for the environment. The cases chosen – from in and outside of Europe are sites that can feed into innovative European Policy on sustainable development. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Netherlands - - - WEGO - - - H2020-MSCA-ITN-2017 - - - 764908 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 185 076 - - - Evolution of cell fate decision during development - - - EUR 185 076 - - - France - - - Research Organisations - - "During development cells progressively acquire specific features that result in the definition of cellular fates.Inter- and intra-specific homologous cell lineages show significant variation in the adoption of particular cell - fates. Yet, at present the genetic and molecular mechanisms underlying these intra-specific changes in cell fate and how variation in cell fates is biased during evolutionary trajectories are largely unknown. In this project I will use the vulva - system in genetically tractable nematodes to i)identify the molecular basis of intraspecific cell fate variation and ii)to investigate whether evolutionary trajectories in cell fate variation are developmentally constrained in distinct nematode - genera. In Caenorhabditis species, among the six ""vulva precursor cells"", only one termed P3.p shows fate evolution within and among species.In contrast,in Oscheius species(sister genus)other vulva precursor cells fates evolve faster, named P4.p - and P8.p. The work is structured into two main objectives. First,I will investigate the molecular and genetic basis of intraspecific P3.p cell fate variation in C.elegans using quantitative genetics, whole-genome sequencing and modern genome editing - techniques. Second,I will probe the role of developmental constrains in biasing evolutionary trends of cell fate variation by using a combination of random mutagenesis and quantitative genetics.This project will contribute to integrate the field of - evolution of development with a population and quantitative genetic framework and will provide a mechanistic genetic understanding of cell fate variation during development and evolution at several evolutionary scales. Based on a highly successful - research group in a worldwide-recognized institute and its network of collaborators,it will allow me to obtain a strong background in evolutionary theory,nematode development,genome bioinformatic skills and quantitative genetics,building on my strong - molecular and developmental background" - - 2019-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - EvoCellFate - - - H2020-MSCA-IF-2016 - - - 751530 - - - - - UNIVERSITE DE BORDEAUX - ECOLE NATIONALE SUPERIEURE DES MINES DE PARIS - ECOLE NATIONALE D'INGENIEURS DE TARBES - LULEA TEKNISKA UNIVERSITET - UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA - BCAM - BASQUE CENTER FOR APPLIED MATHEMATICS - FUNDACION TECNALIA RESEARCH & INNOVATION - SAFRAN SA - SIRRIS HET COLLECTIEF CENTRUM VAN DE TECHNOLOGISCHE INDUSTRIE - - - EUR 2 316 282,12 - - - European Network for Alloys Behaviour Law Enhancement - - - EUR 2 316 282,12 - - - France - France - France - Sweden - Spain - Spain - Spain - France - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - - ENABLE aims to train early-stage researchers in what is referred to as an outstanding challenge for the future of manufacturing: developing novel solutions for forecasting and mastering processes relevant for all factories using metallic alloys. - - - 2022-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - France - - - ENABLE - - - H2020-MSCA-ITN-2017 - - - 764979 - - - - - DUBLIN CITY UNIVERSITY - - - EUR 175 866 - - - Knowledge Discovery in Data as Collaboration of Human and Software Actors - - - EUR 175 866 - - - Ireland - - - Higher or Secondary Education Establishments - - The KDD-CHASER project aims to develop a process model and software platform for collaborative knowledge discovery in data (KDD). Traditionally, KDD has been an expert-driven process, but more recently, special types of KDD - processes have begun to emerge that involve non-expert individuals in various roles. With sufficiently intelligent software tools, it is even possible for such individuals to take charge of the process and use KDD to extract useful knowledge from - their own personal data, but this possibility is not adequately covered by the established process model of KDD. The project addresses this problem by exploring the requirements of incorporating autonomous software and non-expert humans as actors in - the KDD process and distilling these into a new process model, consisting of a data model and a workflow model, that satisfies the requirements. - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Ireland - - - KDD-CHASER - - - H2020-MSCA-IF-2016 - - - 746837 - - - - - THE UNIVERSITY OF SUSSEX - - - EUR 183 454,80 - - - Quantum Sensing with Quantum Optical Networks - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Quantum sensing exploits effects such as entanglement to enhance the sensitivity of measurement devices. In the last decade we have witnessed a significant advance in experimental platforms such as trapped ion setups and - superconducting circuits. These systems are never free from noise and dissipation, however, interactions between qubits and photons or phonons can be controlled with lasers or external fields. Even in strong dissipative regimes, cooperative effects - may induce complex quantum dynamics with emergent phenomena such as non-equilibrium phase transitions and multistability. The question then arises whether we can exploit those many-body effects in robust metrological protocols. - - - 2020-06-03, Grant Agreement signed - - - 2018-06-04 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - QUSON - - - H2020-MSCA-IF-2016 - - - 752180 - - - - - THE UNIVERSITY OF SUSSEX - - - EUR 183 454,80 - - - Restart of blocked replication fork at replication fork barrier - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Errors in replication of DNA lead to serious diseases like cancer, inherited neurological and muscular diseases. Replication is constantly challenged by various obstacles that can result in error-prone replication. Replication - fork barriers (RFBs) include proteins bound to DNA, structure forming sequences and DNA/RNA hybrids. Replication forks (RFs) stalled or blocked at these barriers can be rescued by a converging fork. But if this fails blocked RF must be restarted to - complete replication. Restart using homologous recombination (HR) can lead to gross chromosomal rearrangements and copy number variations. The newly restarted replication fork is also prone to slippage leading to mutation and rearrangements. - - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - Rep. Fork Restart - - - H2020-MSCA-IF-2016 - - - 749631 - - - - - EBERHARD KARLS UNIVERSITAET TUEBINGEN - MEDIZINISCHE UNIVERSITAET WIEN - ACADEMISCH ZIEKENHUIS GRONINGEN - KATHOLIEKE UNIVERSITEIT LEUVEN - KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN - REGION HOVEDSTADEN - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - KING'S COLLEGE LONDON - ABX CRO ADVANCED PHARMACEUTICAL SERVICES FORSCHUNGSGESELLSCHAFT MBH - PHILIPS ELECTRONICS NEDERLAND B.V. - SIEMENS HEALTHCARE GMBH - - - EUR 3 858 940,08 - - - Innovative Training Network towards raising and supporting the next generation of creative and entrepreneurial cross-speciality imaging experts - - - EUR 3 858 940,08 - - - Germany - Austria - Netherlands - Belgium - Germany - Denmark - France - United Kingdom - Germany - Netherlands - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Modern medicine seeks to personalize diagnosis and treatment to the needs of individual patients. Personalized medicine approaches use non-invasive imaging to detect and characterize disease. While anatomical and molecular - imaging systems have become a commodity, these systems have also grown complex. Complexity is further increased by the introduction of combined (hybrid) imaging systems, such as PET/CT, SPECT/CT or PET/MR. Within the context of hybrid imaging, these - systems provide multi-parametric image information that has proven promising in rendering diagnoses and subsequent therapeutic management of patients more effective. The growing complexity of diagnostic and therapeutic regimens in light of the drive - to integrate multiple layers of biomarker information no longer supports the operation of hybrid imaging modalities by singular specialists, but instead requires a new generation of open-minded, technology-fluent and applications-oriented experts. - - - 2021-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - HYBRID - - - H2020-MSCA-ITN-2017 - - - 764458 - - - - - THE UNIVERSITY OF BIRMINGHAM - UNIVERSITEIT MAASTRICHT - THE UNIVERSITY OF READING - LEIBNIZ-INSTITUT FUR ANALYTISCHE WISSENSCHAFTEN-ISAS-EV - UNIVERSITAETSKLINIKUM WUERZBURG - KLINIKUM DER BAYERISCHEN JULIUS-MAXIMILIANS-UNIVERSITAT - ALACRIS THERANOSTICS GMBH - UNIVERSIDAD DE SANTIAGO DE COMPOSTELA - - - EUR 3 881 891,88 - - - TArgeting Platelet Adhesion receptors in thrombosiS - - - EUR 3 881 891,88 - - - United Kingdom - Netherlands - United Kingdom - Germany - Germany - Germany - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - TAPAS will position Europe at the forefront of innovative research to prevent thrombosis and thromboinflammation, and will train a uniquely-qualified cohort of ESRs in a highly intersectorial and multi-disciplinary programme - that will equip them with the knowledge and transferable skills required in the broad biomedical sector. The research will focus on platelets which are small cells in the blood that play a critical role in prevention of excessive bleeding following - injury (haemostasis). Activation of platelets in diseased vessels gives rise to thrombotic disorders such as heart attack and stroke, two of the major causes of morbidity and mortality. Patients at risk of thrombosis are treated with medicines that - inhibit platelets for life, but many patients still undergo thrombotic episodes or encounter serious bleeds through diminished haemostasis. There is thus an urgent need for novel and safe anti-platelet medicines that powerfully target thrombosis but - preserve haemostasis. In TAPAS, an original and innovative approach will be undertaken to find new ways to target thrombosis through co-operation of academic experts in distinct disciplines with key skills from the private sector. TAPAS will generate - and integrate knowledge from analytical complex ‘omics’, advanced microscopy, cell biology, microfluidics, in vivo models, contemporary systems biology and high throughput screens to identify new targets for therapeutic intervention and novel lead - compounds or biologics. The research skills developed in this programme are applicable to other complex diseases and represent essential training in modern day research for the next cohort of academic and private sector scientists that are able to - convert complex biological understanding into new medicines. The shared knowledge and close interaction between beneficiaries and partners makes this programme ideally suited to an EJD and will deliver 15 ESRs in 21st century biomedical research. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-EJD - European Joint Doctorates - - - United Kingdom - - - TAPAS - - - H2020-MSCA-ITN-2017 - - - 766118 - - - - - UNIVERSITETET I OSLO - - - EUR 208 400,40 - - - Interfaces for Relational Listening: body, telematics, memory, migration - - - EUR 208 400,40 - - - Norway - - - Higher or Secondary Education Establishments - - In the European context of migration and diasporas, and at the intersection of sound art, music cognition, psychology and human-computer interaction, this project will develop INTIMAL: a novel physical-virtual “embodied - system” for relational listening. Through the artistic practice of telematic sonic performance this system will interconnect people’s bodily motion and voice with their memories and dreams of distant locations. - - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Norway - - - INTIMAL - - - H2020-MSCA-IF-2016 - - - 752884 - - - - - UNIVERSITETET I OSLO - - - EUR 208 400,40 - - - Deciphering the mycobiome of indoor environments by high-throughput sequencing - - - EUR 208 400,40 - - - Norway - - - Higher or Secondary Education Establishments - - Fungi have ubiquitous distribution in natural ecosystems and are also common in the built environment, where people spend major parts of their lifetime. When moisture is present, fungal growth can cause material deterioration - and adverse effects on the occupant’s health. Traditional methods for analyzing the indoor mycobiome, such as culturing and microscopy, have severe limitations. - - 2020-02-29, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Norway - - - MycoIndoor - - - H2020-MSCA-IF-2016 - - - 741332 - - - - - CONSIGLIO NAZIONALE DELLE RICERCHE - Koninklijk Instituut voor het Kunstpatrimonium - THE CYPRUS INSTITUTE - USTAV TEORETICKE A APLIKOVANE MECHANIKY AVCR - DEUTSCHES ARCHAOLOGISCHES INSTITUT - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - CONSORCIO PARA LA CONSTRUCCION, EQUIPAMIENTO Y EXPLOTACION DEL CENTRO NACIONAL DE INVESTIGACION SOBRE LA EVOLUCION HUMANA - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - DIGITAL RESEARCH INFRASTRUCTURE FOR THE ARTS AND HUMANITIES - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - Magyar Tudomanyos Akademia Atommagkutato Intezete - THE DISCOVERY PROGRAMME : CENTRE FOR ARCHAEOLOGY AND INNOVATION IRELAND - Israel Antiquities Authority - CENTRAL EUROPEAN RESEARCH INFRASTRUCTURE CONSORTIUM EUROPEAN RESEARCH INFRASTRUCTURE CONSORTIUM - PIN SOC.CONS. A R.L. - SERVIZI DIDATTICI E SCIENTIFICI PER L UNIVERSITA DI FIRENZE - MINISTERIE VAN ONDERWIJS, CULTUUR EN WETENSCHAP - UNIWERSYTET MIKOLAJA KOPERNIKA W TORUNIU - LABORATORIO NACIONAL DE ENGENHARIA CIVIL - JAVNI ZAVOD REPUBLIKE SLOVENIJE ZA VARSTVO KULTURNE DEDISCINE - UNIVERSITY COLLEGE LONDON - - - EUR 3 999 449 - - - The European Research Infrastructure for Heritage Science Preparatory Phase - - - EUR 3 999 449 - - - Italy - Belgium - Cyprus - Czech Republic - Germany - Spain - Spain - France - France - Greece - Hungary - Ireland - Israel - Italy - Italy - Netherlands - Poland - Portugal - Slovenia - United Kingdom - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - - E-RIHS PP is a coordination and support action addressing the topic “Preparatory Phase and support to early phase of ESFRI projects” within the call H2020-INFRADEV-02-2016. The specific action addressed by this project is the - preparation of E-RIHS, the European Research Infrastructure for Heritage Science (HS), one of the six new projects which entered the ESFRI Roadmap in 2016, and the only research infrastructure project in the Social and Cultural Innovation section of - the Roadmap. E-RIHS will help the preservation of the World’s Heritage by enabling cutting-edge research in HS, liaising with governments and heritage institutions to promote its constant development and, finally, raising the appreciation of the - large public for cultural and natural heritage and the recognition of its historic, social and economic significance. - - 2020-01-31, ongoing project - - - 2017-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-02-2016 - Preparatory Phase and support to early phase of ESFRI projects - - - CSA - Coordination and support action - - - Italy - - - E-RIHS PP - - - H2020-INFRADEV-2016-2 - - - 739503 - - - - - NATIONAL UNIVERSITY OF IRELAND GALWAY - - - EUR 187 866 - - - Treatment of contaminated land using a biochar/media mixture - - - EUR 187 866 - - - Ireland - - - Higher or Secondary Education Establishments - - Waste disposal and treatment is a major source of contamination of soils, surface and groundwater, and accounts for 35% of the 1.1 million contaminated sites in Europe. Leaching of the organic solvent trichloroethylene (TCE) - into groundwater has been identified as a primary issue with unlined landfills , affecting up to 70% of leachates tested. Mainly used as a metal degreaser and dry-cleaning reagent, TCE is difficult to treat; current treatment methods, such as - anaerobic digestion or air stripping , are ineffective and/or expensive. This project will investigate the use biochar, or other appropriate media, for treatment of TCE contaminated water via two technologies - permeable reactive interceptors (PRIs) - and permeable contaminant retaining filter (PCRF) bags. This novel, low-cost solution will address the requirements of European Union (EU) legislation, including the Water Framework Directive (WFD). The project will be based at the National - University of Ireland, Galway (NUIG) with supervision by Dr Mark Healy (GeoEnvironmental Engineering Research Group – GENE) and support from Dr Florence Abram (Functional Environmental Microbiology - FEM). As the applicant has experience in TCE - treatment from a microbial background, this highly novel, interdisciplinary proposal will compliment and strengthen her existing skillset by approaching this technology from an engineering perspective, with support from a research group that has a - strong track record in this research area. With detailed career development assistance, multiple opportunities to further her strong publication record, access to numerous and varied fora for dissemination of results and support for IP exploitation, - this proposal will have a significant impact in reintegrating the applicant back into the EU research community from her current research position in New Zealand. - - 2019-07-09, ongoing project - - - 2017-07-10 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Ireland - - - TOOLBOX - - - H2020-MSCA-IF-2016 - - - 748106 - - - - - UNIVERSITETET I OSLO - - - EUR 196 400,40 - - - The evolutionary origins and consequences of human-commensalism in Passer sparrows - - - EUR 196 400,40 - - - Norway - - - Higher or Secondary Education Establishments - - Human-commensal species are almost constantly present in our daily lives; they are the mice in our fields or the sparrows in our gardens. The evolutionary trajectories of these species are intertwined with our own through the - development of agriculture and human civilization, yet we know surprisingly little about their origins. - - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Norway - - - EVOSPARROW - - - H2020-MSCA-IF-2016 - - - 748299 - - - - - NATIONAL UNIVERSITY OF IRELAND GALWAY - - - EUR 248 063,40 - - - Carabids as biocontrol agents for slugs in Oregon and Ireland - a novel and interdisciplinary approach to determine key malacophagous species and beneficial management options - - - EUR 248 063,40 - - - Ireland - - - Higher or Secondary Education Establishments - - One of the challenges identified under Horizon 2020 is the building of a sustainable agri-food industry. Agricultural pests such as slugs are major contributors to financial losses in the farming sector and the use of - pesticides, which is currently the mainstay of control, is an unsustainable management option due to their toxicity to non-target species and consumers but also because of their cost and variable efficacy. Biocontrol poses a more sustainable approach - to pest control, but the only commercially available agent against slugs is the nematode Phasmarhabditis hermaphrodita which is ineffective against a number of key pest species, has a short shell life and is not permitted in countries outside of - Europe (e.g. USA). CaraSlug aims to assess the potential of native carabid species as biocontrol agents against slug pests in Oregon and Ireland. For the first time, high-throughput sequencing and real-time PCR will be used in combination to analyse - the gut contents of carabids collected over one year from vulnerable crops. Carabid species which are found to feed extensively on slugs and are abundant in crops at times when major slug damage occurs will be selected for feeding trials in the - laboratory to further understand their feeding behaviour and biocontrol potential. By comparing the abundance of both pest and predator species and by determining the availability of alternative prey in differently managed crops e.g. with and without - beetle banks over a year, management systems which provide optimum conditions for malacophagous carabid species will be identified. This project is interdisciplinary, combining ‘classic’ ecology and environmental management approaches with the latest - advances in molecular biology and both the experienced researcher and the hosts will benefit greatly from the combined team’s expertise. By directly involving farmers in our research, this project will also form an important link between academia and - the community. - - 2020-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Ireland - - - CaraSlug - - - H2020-MSCA-IF-2016 - - - 750296 - - - - - UNIVERSITE GRENOBLE ALPES - UNIVERSITY OF LEEDS - EUROPEAN SPALLATION SOURCE ERIC - AARHUS UNIVERSITET - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - UNIVERSITAET HAMBURG - NATIONAL UNIVERSITY OF IRELAND MAYNOOTH - UNIVERSITY OF SURREY - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - - - EUR 3 243 291,48 - - - RAtionalising Membrane Protein crystallisation - - - EUR 3 243 291,48 - - - France - United Kingdom - Sweden - Denmark - Ireland - Germany - Ireland - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Membrane proteins form more than 85% of drug targets, but just 600 unique membrane protein crystal structures have been determined. A better understanding of how to crystallize membrane proteins reliably is therefore urgently - required. The Innovative Training Network “RAtionalising Membrane Protein crystallisation” – RAMP will bring together cutting-edge physical chemistry methods for crystallisation condition control and phase diagram exploration, and the development of - new lipids and screens in conjunction with industry with the most challenging biological problems. The network includes expert academic and industrial research groups in crystallisation theory, methods development, membrane protein crystallography, - drug development and novel structural techniques like time-resolved and neutron crystallography. We will develop new, rational methods for crystallising membrane proteins, focusing particularly on transporters that are also interesting drug targets. - The new robust crystallisation methods will also allow us to use emerging European research infrastructures like XFEL or ESS to gain insight into membrane protein function because the techniques will provide the necessary precise control of crystal - size. - - - 2021-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - France - - - RAMP - - - H2020-MSCA-ITN-2016 - - - 722687 - - - - - UNIVERSITETET I OSLO - - - EUR 208 400,40 - - - Linking micro- and macroevolution: macroevolutionary quantitative genetics of Drosophila wing morhology - - - EUR 208 400,40 - - - Norway - - - Higher or Secondary Education Establishments - - The striking mismatch between evolution at short (microevolution) and long (macroevolution) time scales is a major remaining problem in evolutionary biology (the paradox of stasis). FLYWING will apply novel quantitative - genetic theories and statistical methods to analyses of exceptionally high quality data to make a major step forward to solve the paradox of stasis. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Norway - - - FLYWING - - - H2020-MSCA-IF-2016 - - - 747338 - - - - - THE UNIVERSITY OF SUSSEX - - - EUR 183 454,80 - - - Representing Idiocy and Intellectual Disability in Early Modern English Literature, 1500-1640 - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - My project will consider several examples of natural or artificial fools, clowns, idiots portrayed in the literary production of England from 1500 to 1640 and will investigate how early modern notions of intellectual - deficiency primarily in medicine but also in society shaped the creation of those same figures. My literary corpus will include not only dramatic texts but also jestbooks, which notably offer a wealth of information on real or fantastic fools of the - time, and poetical works. Folly in the sense of lack of wit, rather than the loss of it – which is the definition of madness – will be my primary focus. While the theme of madness in connection with early modern literature has been explored at - length, the same cannot be said for cognitive disability or lack of intelligence. The main reason for this is that only recently have a small number of scholars started to discuss and bring together historical, medical and legal notions of natural - folly in the early modern period. In the past, remarkable attempts at historicizing natural folly have bordered into discourses on madness and analogue mental disorders thus blurring the difference between the two conditions, the same difference that - Renaissance legislation actually sought to define. In the wake of very recent trends in disability studies, therefore, I will use legal but especially medical theories of foolishness and idiocy to explore the characters of my corpus and to highlight, - on a scientific and social basis, their separate nature from those conceived of as lunatics. Furthermore, because the exploration of intellectual disability in my period of interest is relatively a new field, I expect to find in the fools of my - corpus hints to theories or assumptions that have not been discussed yet. - - 2019-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - Renaissance Idiocy - - - H2020-MSCA-IF-2016 - - - 745642 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - THE UNIVERSITY OF MANCHESTER - VRIJE UNIVERSITEIT BRUSSEL - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - FONDAZIONE EDMUND MACH - INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE - UNIVERSIDAD DE ZARAGOZA - LALLEMAND SAS - SINGER INSTRUMENT COMPANY LIMITED - NOVOZYMES A/S - - - EUR 3 684 848,76 - - - Generation of new yeast strains for improved flavours and aromas in beer and wine - - - EUR 3 684 848,76 - - - Ireland - United Kingdom - Belgium - Spain - Italy - France - Spain - France - United Kingdom - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - This project aims to train the next generation of researchers to provide knowledge and expertise for two major industries in the EU, namely the beer and wine industries. Yeasts belonging to the Saccharomyces stricto sensu - group are the workhorses of these industries and an understanding of how yeasts contribute to the complex flavours and aromas of beer and wine is essential for the improvement of existing fermentation technology and for the development new - flavoursome beverages. - - 2021-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Ireland - - - Aromagenesis - - - H2020-MSCA-ITN-2017 - - - 764364 - - - - - THE UNIVERSITY OF SUSSEX - - - EUR 195 454,80 - - - Zebrafish colour vision: a functional approach to studying outer retinal wiring strategies - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Colour vision is critical animals to navigate their environment. Here, two or more spectrally distinct cone-photoreceptor types are needed in the retina which must be postsynaptically combined to extract contrasts in wavelength. - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ColourFish - - - H2020-MSCA-IF-2016 - - - 748716 - - - - - UNIVERSITETET I OSLO - - - EUR 196 400,40 - - - Functional dissection of the head-direction circuit in mouse retrosplenial cortex. - - - EUR 196 400,40 - - - Norway - - - Higher or Secondary Education Establishments - - Head direction (HD) cells provide directional information during spatial navigation and thus act as an - - 2019-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Norway - - - RSCHD - - - H2020-MSCA-IF-2016 - - - 753608 - - - - - UNIVERSITAET KASSEL - AARHUS UNIVERSITET - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - IBM RESEARCH GMBH - INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE - NVISION IMAGING TECHNOLOGIES GMBH - TTI-Technologie-Transfer-Initiative GmbH - TECHNISCHE UNIVERSITAET MUENCHEN - TECHNISCHE UNIVERSITAET WIEN - UNIVERSITAT DES SAARLANDES - UNIVERSITAET ULM - THALES SA - COMMUNAUTE D' UNIVERSITES ET ETABLISSEMENTS UNIVERSITE BOURGOGNE - FRANCHE - COMTE - - - EUR 3 881 935,42 - - - Quantum-enhanced Sensing via Quantum Control - - - EUR 3 881 935,42 - - - Germany - Denmark - France - France - Switzerland - France - Germany - Germany - Germany - Austria - Germany - Germany - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Corinna Hahn - Tel.: +49 681 95 92 3362 - Fax: +49 681 95 92 3370 - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - Quantum technologies aim to exploit quantum coherence and entanglement, the two essential elements of quantum physics. Successful implementation of quantum technologies faces the challenge to preserve the relevant nonclassical - features at the level of device operation. It is thus deeply linked to the ability to control open quantum systems. The currently closest to market quantum technologies are quantum communication and quantum sensing. The latter holds the promise of - reaching unprecedented sensitivity, with the potential to revolutionize medical imaging or structure determination in biology or the controlled construction of novel quantum materials. Quantum control manipulates dynamical processes at the atomic or - molecular scale by means of specially tailored external electromagnetic fields. The purpose of QuSCo is to demonstrate the enabling capability of quantum control for quantum sensing and quantum measurement, advancing this field by systematic use of - quantum control methods. QuSCo will establish quantum control as a vital part for progress in quantum technologies. - - 2021-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - QuSCo - - - H2020-MSCA-ITN-2017 - - - 765267 - - - - - ROYAL COLLEGE OF SURGEONS IN IRELAND - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - UNIVERSIDAD COMPLUTENSE DE MADRID - INSTITUTE OF EXPERIMENTAL MEDICINE - HUNGARIAN ACADEMY OF SCIENCES - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - CENTRO DE INVESTIGACION BIOMEDICA EN RED ENFERMEDADES NEURODEGENERATIVAS - SARISSA BIOMEDICAL LIMITED - BIOTALENTUM TUDASFEJLESZTO KFT - FUNDACION TEOFILO HERNANDO - - - EUR 3 487 463,28 - - - Interdisciplinary training network on the purinergic P2X7 receptor to control neuroinflammation and hyperexcitability in brain diseases. - - - EUR 3 487 463,28 - - - Ireland - Germany - Spain - Hungary - Germany - Spain - United Kingdom - Hungary - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - - Brain disorders affect ~179 million people and their families in Europe alone, with an annual cost to the taxpayer estimated at €800 billion- a greater economic burden than cardiovascular disease and cancer combined. Despite - diverse etiology, overlap in clinical symptoms and comorbidities between brain disorders suggests shared patho-mechanisms. In particular, hyperexcitible states driven by glial activation and neuroinflammation appear near ubiquitous. Targeting these - mechanisms offers the potential to ameliorate symptoms and reverse disease progression across a broad span of brain disorders. Functioning as a gatekeeper to neuroinflammation and mechanistic link between neuronal hyperexcitability and glial - activation, the ATP-gated, ionotropic purinergic P2X7 receptor (P2X7R) offers the most promising target for pharmacological intervention in the neuroinflammation-hyperexcitability pathway, to date. With breakthroughs in understanding P2X7R function, - highly promising effects demonstrated for antagonists in models of brain disease and vast investment in P2X7R-related drug development programmes, now is the perfect time to pool resources. PurinesDX brings together global leaders in translational - research in purinergic signalling, Europe’s leading clinical specialists in a broad range of brain diseases, and industrial partners specializing in drug and biomarker development. Sharing unique genetic tools, newly developed diagnostic devices and - novel, selective and brain-stable P2X7R antagonists, the synergism facilitated within PurinesDX will extend to the training of an urgently needed new generation of highly skilled, innovative, creative and entrepreneurial scientists. Alongside the - provision of this interdisciplinary, international and intersectoral environment, an original and high level training in state-of-the-art neuroscience will be provided, nurturing a cohort of highly competitive researchers with potential to drive a - new era of neuroscience research. - - 2021-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Ireland - - - PurinesDX - - - H2020-MSCA-ITN-2017 - - - 766124 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - ACADEMISCH ZIEKENHUIS LEIDEN - FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION - THE UNIVERSITY OF LIVERPOOL - ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOCIENCIAS - MEDICAL RESEARCH COUNCIL - JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN - INSTITUT FUR MOLEKULARE BIOLOGIE GGMBH - UNIVERSITY OF DUNDEE - Novo Nordisk A/S - - - EUR 3 407 194,44 - - - European Research Training to Decipher The Ub Code : identification of potential biomarkers and drug targets - - - EUR 3 407 194,44 - - - France - Germany - Netherlands - Switzerland - United Kingdom - Spain - United Kingdom - Germany - Germany - United Kingdom - Denmark - - - Research Organisations - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Essential role of protein modification by members of the Ubiquitin family: Post-translational modifications (PTM) by members of the Ubiquitin (Ub) family represent an efficient way to regulate protein function at several - levels: to change their localisation, activity, their interaction with partner proteins or their stability at the right time and cellular compartment, according to the cell requirements. Defects in this homeostatic equilibrium result in pathologies - such as cancer, neurodegeneration, inflammation or multiple infections. For this reason, this research area has become very attractive for fundamental scientists as well as for the pharmaceutical industry aiming to identify potential targets for - therapeutic intervention. Ub family members hold a homeostatic equilibrium within the cell and are interconnected in various ways including the regulation of enzymes that control the modified status of target proteins. Interestingly, Ub and Ub-like - (UbL) proteins can modify themselves, forming intricate and complex chains. This landscape has recently expanded with the discovery of the formation of heterologous chains among UbL molecules including SUMO or NEDD8 but also other PTMs such as - phosphorylation or acetylation. This unsuspected complexity of what is now known as the «Ubiquitin Code», which is an unknown universal language that needs to be deciphered to understand protein homeostasis and its associated pathologies. To decrypt - this complex code requires joint collaborative multidisciplinary efforts at all levels, including the use of distinct molecular systems and model organisms and the latest technological developments to explore chemical, biochemical, molecular, - pharmacological and clinical aspects of protein modification by members of the Ub family. UbiCODE represents an unprecedented effort to understand this code in an integrated manner. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - France - - - UbiCODE - - - H2020-MSCA-ITN-2017 - - - 765445 - - - - - INSTITUTE OF DEVELOPMENT STUDIES - INSTITUTE OF DEVELOPMENT STUDIES - EUROPEAN UNIVERSITY INSTITUTE - - - EUR 2 499 126,50 - - - Pastoralism, Uncertainty and Resilience: Global Lessons from the Margins - - - EUR 2 499 126,50 - - - United Kingdom - United Kingdom - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Existing institutions, legal frameworks and governance systems are not equipped to respond to growing global uncertainties and the challenges of building resilience. Radical new thinking is needed. Important lessons - potentially can come from surprising quarters. Drawing insights from pastoral areas across three continents, we will ask: What lessons can we learn from pastoral systems responding to rapid change that help us understand how to live with uncertainty - and build resilience? Learning from the margins – through a reversal in conventional policy learning and debate - this project will draw out principles from deeply-embedded, culturally-rich responses to rapid change and uncertainty in pastoral areas - in Africa (Borana, Ethiopia), Asia (Qinghai-Tibet, China) and Europe (Sardinia, Italy). - - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - PASTRES - - - ERC-2016-ADG - - - 740342 - - - - - OTTO-FRIEDRICH-UNIVERSITAET BAMBERG - COPENHAGEN BUSINESS SCHOOL - CRANFIELD UNIVERSITY - INSTITUT FUER ARBEITSMARKT- UND BERUFSFORSCHUNG (IAB) DER BUNDESAGENTUR FUER ARBEIT - TOULOUSE BUSINESS SCHOOL -TBS - VAASAN YLIOPISTO - STICHTING VU - AIRBUS SAS - - - EUR 3 947 612,40 - - - Global mobility of employees - - - EUR 3 947 612,40 - - - Germany - Denmark - United Kingdom - Germany - France - Finland - Netherlands - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Other - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Promoting labour mobility across Europe is a central objective of the Europe 2020 Strategy and it aims to tackle increasing labour and skill shortages in the EU. Cross-border labour mobility is expected to benefit both - individual citizens, employers and the aggregate economy. In addition, intra-EU mobility is a means to foster European integration. Although migration into OECD countries increases, driven largely by people moving within the EU, migration into and - within Europe is still short of target levels. Despite a favourable legal framework for mobility, migrants still face a wide range of problems and obstacles that hamper cross-border labour mobility. Employment prospects for immigrants are below those - of natives and overqualification, i.e. employment below skill levels, is widespread in most European countries. Consequently, the growth potential of immigrants is far from realised. Little is known about transnational mobility patterns and the - length of migration episodes as well as about retention processes of foreign employees. There is considerable scope to make existing labour mobility more efficient and beneficial for all parties involved. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - GLOMO - - - H2020-MSCA-ITN-2017 - - - 765355 - - - - - UNIVERSITETET I OSLO - - - EUR 196 400,40 - - - Images in Exile:Gender and representations among Syrian Kurdish women in Norway - - - EUR 196 400,40 - - - Norway - - - Higher or Secondary Education Establishments - - The project Images in Exile (IMEX) addresses the current refugee crisis and its implications for Syrian Kurdish women in Europe. It challenges images about Muslim women, who are often the subject of debates on the supposed - dichotomy between an imagined secular progressive West and religious backwards East. Kurdish women disrupt this dichotomy through an alternative portrayal in global media. Whereas Kurds were previously often pictured as terrorists, backward, and - conservative, they are now presented as courageous fighters against, and victims of, Islamic terrorism; and as progressive forces that include women in their ranks. Ideas about progressive, feminist and secular forms of governance are strongly - developed in Kurdish political thought, and central in local self-representations. - - 2019-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Norway - - - IMEX - - - H2020-MSCA-IF-2016 - - - 753935 - - - - - NATIONAL UNIVERSITY OF IRELAND GALWAY - - - EUR 175 866 - - - Novel, highly effective and selective anticancer metallodrugs - - - EUR 175 866 - - - Ireland - - - Higher or Secondary Education Establishments - - Dr. Leila Tabrizi, an Iranian national, is making an application to this programme to carry out a 24 months project in the area of medicinal chemistry in the group of Dr. A. Erxleben at the National University of Ireland, Galway. - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Ireland - - - TSPO METALLODRUGS - - - H2020-MSCA-IF-2016 - - - 749621 - - - - - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - AALTO-KORKEAKOULUSAATIO - ACADEMISCH ZIEKENHUIS LEIDEN - ATHENS UNIVERSITY OF ECONOMICS AND BUSINESS - RESEARCH CENTER - BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION - BAUHAUS-UNIVERSITAET WEIMAR - BERGISCHE UNIVERSITAET WUPPERTAL - Bloomfield Science Museum Jerusalem (BSMJ) - CARDIFF UNIVERSITY - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - CONSIGLIO NAZIONALE DELLE RICERCHE - CINECA CONSORZIO INTERUNIVERSITARIO - DANMARKS TEKNISKE UNIVERSITET - DEBRECENI EGYETEM - DE MONTFORT UNIVERSITY - ECOLE NORMALE SUPERIEURE - Eidgenössische Technische Hochschule Zürich - FONDEN TEKNOLOGIRADET - FORSCHUNGSZENTRUM JULICH GMBH - FORTISS GMBH - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - FUNDACAO D. ANNA SOMMER CHAMPALIMAUD E DR. CARLOS MONTEZ CHAMPALIMAUD - HEINRICH-HEINE-UNIVERSITAET DUESSELDORF - HELSINGIN YLIOPISTO - HITS GGMBH - CENTRE HOSPITALIER UNIVERSITAIRE VAUDOIS - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - Institut du Cerveau et de la Moelle épinière - INSTITUTE OF EXPERIMENTAL MEDICINE - HUNGARIAN ACADEMY OF SCIENCES - Institute of Science and Technology Austria - INSTITUT JOZEF STEFAN - INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE - INSTITUT PASTEUR - JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN - KARLSRUHER INSTITUT FUER TECHNOLOGIE - KAROLINSKA INSTITUTET - KING'S COLLEGE LONDON - KUNGLIGA TEKNISKA HOEGSKOLAN - LABORATORIO EUROPEO DI SPETTROSCOPIE NON LINEARI - LINNEUNIVERSITETET - MEDIZINISCHE UNIVERSITAT INNSBRUCK - ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON - NORGES MILJO-OG BIOVITENSKAPLIGE UNIVERSITET - OSTERREICHISCHE STUDIENGESELLSCHAFTFUR KYBERNETIK VEREIN - RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - SABANCI UNIVERSITESI - SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO SANT'ANNA - STICHTING CENTRUM VOOR WISKUNDE EN INFORMATICA - STICHTING KATHOLIEKE UNIVERSITEIT - STIFTUNG FZI FORSCHUNGSZENTRUM INFORMATIK AM KARLSRUHER INSTITUT FUR TECHNOLOGIE - THE RESEARCH COMMITTEE OF THE TECHNICAL UNIVERSITY OF CRETE - TECHNISCHE UNIVERSITAET DRESDEN - TECHNISCHE UNIVERSITAET GRAZ - TECHNISCHE UNIVERSITAET MUENCHEN - TEL AVIV UNIVERSITY - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE HEBREW UNIVERSITY OF JERUSALEM - THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN - THE UNIVERSITY OF EDINBURGH - THE UNIVERSITY OF MANCHESTER - UNIVERSIDAD AUTONOMA DE MADRID - UNIVERSIDAD DE CASTILLA - LA MANCHA - UNIVERSIDAD DE GRANADA - UNIVERSIDADE DO MINHO - UNIVERSIDAD POLITECNICA DE MADRID - UNIVERSIDAD REY JUAN CARLOS - UNIVERSITA DEGLI STUDI DI PAVIA - UNIVERSITAET BERN - UNIVERSITAET BIELEFELD - UNIVERSITAETSKLINIKUM AACHEN - UNIVERSITAETSKLINIKUM HAMBURG-EPPENDORF - UNIVERSITAT ZURICH - UNIVERSITAT DE BARCELONA - UNIVERSIDAD POMPEU FABRA - UNIVERSITE D'AIX MARSEILLE - UNIVERSITE DE BORDEAUX - UNIVERSITEIT ANTWERPEN - UNIVERSITETET I OSLO - UNIVERSITY COLLEGE LONDON - UPPSALA UNIVERSITET - WEIZMANN INSTITUTE OF SCIENCE - TECHNISCHE UNIVERSITAT DARMSTADT - UNIVERSITE DE GENEVE - UNIVERSITY OF GLASGOW - MEDICAL RESEARCH COUNCIL - UNIVERSITAET HAMBURG - HUMBOLDT-UNIVERSITAET ZU BERLIN - KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW - ISTITUTO NAZIONALE DI FISICA NUCLEARE - CONSORCI INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER - UNIVERSITA DEGLI STUDI DI MILANO - FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA - ISTITUTO SUPERIORE DI SANITA - UNIVERSITE DE LIEGE - UNIVERSITEIT VAN AMSTERDAM - DEUTSCHES ZENTRUM FUR NEURODEGENERATIVE ERKRANKUNGEN EV - THE UNIVERSITY OF SHEFFIELD - UNIVERSITY OF THE WEST OF ENGLAND, BRISTOL - UNIVERSITY OF SURREY - TTY-SAATIO - UNIVERSITY OF LEEDS - UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6 - THE UNIVERSITY OF SUSSEX - MIDDLESEX UNIVERSITY HIGHER EDUCATION CORPORATION - UNIVERSITE LYON 1 CLAUDE BERNARD - POLITECNICO DI TORINO - UNIVERSITEIT GENT - KATHOLIEKE UNIVERSITEIT LEUVEN - UNIVERSITAET BASEL - STICHTING VU - SWISS INSTITUTE OF BIOINFORMATICS - EUROPEAN BRAIN RESEARCH INSTITUTE R ITA LEVI-MONTALCINI FONDAZIONE*EBRI - SCUOLA NORMALE SUPERIORE - UNIVERSITEIT MAASTRICHT - THE UNIVERSITY OF HERTFORDSHIRE HIGHER EDUCATION CORPORATION - - - EUR 89 000 000 - - - Human Brain Project Specific Grant Agreement 1 - - - EUR 89 000 000 - - - Switzerland - Finland - Netherlands - Greece - Spain - Germany - Germany - Israel - United Kingdom - France - France - Italy - Italy - Denmark - Hungary - United Kingdom - France - Switzerland - Denmark - Germany - Germany - Germany - Portugal - Germany - Finland - Germany - Switzerland - United Kingdom - France - Hungary - Austria - Slovenia - France - France - Germany - Germany - Sweden - United Kingdom - Sweden - Italy - Sweden - Austria - Greece - Norway - Austria - Germany - Germany - Turkey - Italy - Netherlands - Netherlands - Germany - Greece - Germany - Austria - Germany - Israel - United Kingdom - Israel - United Kingdom - United Kingdom - United Kingdom - Spain - Spain - Spain - Portugal - Spain - Spain - Italy - Switzerland - Germany - Germany - Germany - Switzerland - Spain - Spain - France - France - Belgium - Norway - United Kingdom - Sweden - Israel - Germany - Switzerland - United Kingdom - United Kingdom - Germany - Germany - Netherlands - Italy - Spain - Italy - Spain - Italy - Belgium - Netherlands - Germany - United Kingdom - United Kingdom - United Kingdom - Finland - United Kingdom - France - United Kingdom - United Kingdom - France - Italy - Belgium - Belgium - Switzerland - Netherlands - Switzerland - Italy - Italy - Netherlands - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Understanding the human brain is one of the greatest scientific challenges of our time. Such an understanding can provide profound insights into our humanity, leading to fundamentally new computing technologies, and - transforming the diagnosis and treatment of brain disorders. Modern ICT brings this prospect within reach. The HBP Flagship Initiative (HBP) thus proposes a unique strategy that uses ICT to integrate neuroscience data from around the world, to - develop a unified multi-level understanding of the brain and diseases, and ultimately to emulate its computational capabilities. The goal is to catalyze a global collaborative effort. During the HBP’s first Specific Grant Agreement (SGA1), the HBP - Core Project will outline the basis for building and operating a tightly integrated Research Infrastructure, providing HBP researchers and the scientific Community with unique resources and capabilities. Partnering Projects will enable independent - research groups to expand the capabilities of the HBP Platforms, in order to use them to address otherwise intractable problems in neuroscience, computing and medicine in the future. In addition, collaborations with other national, European and - international initiatives will create synergies, maximizing returns on research investment. SGA1 covers the detailed steps that will be taken to move the HBP closer to achieving its ambitious Flagship Objectives. - - 2018-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2."> - - - FETFLAGSHIP - FETFLAGSHIP - - - SGA-RIA - SGA-RIA - - - Switzerland - - - HBP SGA1 - - - H2020-Adhoc-2014-20 - - - 720270 - - - - - Institute of Science and Technology Austria - Institute of Science and Technology Austria - - - EUR 2 410 292 - - - Tracing Evolution of Auxin Transport and Polarity in Plants - - - EUR 2 410 292 - - - Austria - Austria - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Multicellularity in plants evolved independently from other eukaryotes and presents a unique, alternative way how to deal with challenges of life. A major plant developmental module is the directional transport for the plant - hormone auxin. The crucial components are PIN auxin transporters, whose polar, subcellular localization determines directionality of auxin flow through tissues. PIN-dependent auxin transport represents a unique model for studying the functional link - between basic cellular processes, such as vesicle trafficking and cell polarity, and their developmental outcome at the level of the multicellular organism. Despite decades of intensive research, the classical approaches in the established models are - approaching their limits and many crucial questions remain unsolved, in particular related to PIN structure, regulatory motifs and evolutionary origin - - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Austria - - - ETAP - - - ERC-2016-ADG - - - 742985 - - - - - UNIVERSITY OF EAST ANGLIA - UNIVERSITY OF EAST ANGLIA - - - EUR 2 000 000 - - - Getting to the root of ageing: somatic decay as a cost of germline maintenance - - - EUR 2 000 000 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The trade-off between survival and reproduction lies at the core of the evolutionary theory of ageing. Removal of germ cells extends somatic lifespan implying that reduced reproduction frees up resources for survival. - Remarkably, however, the disruption of germline signalling increases lifespan without the obligatory reduction in fecundity, thus challenging the key role of the survival-reproduction trade-off. Recent breakthroughs suggest that protection and repair - of the genome and the proteome of the germ cells is costly and compromised germline maintenance increases mutation rate, which can reduce offspring fitness. Thus, expensive germline maintenance can be a missing link in the puzzle of cost-free - lifespan extension. This hypothesis predicts that when germline signalling is manipulated to increase investment into somatic cells, the germline maintenance will suffer resulting in increased mutation rate and reduced offspring fitness, even if - total fecundity is unaffected. I propose a research program at the interface of evolutionary biology and biogerontology that focuses on phenotypic and evolutionary costs of germline maintenance. First, I will genetically manipulate germline - signalling to boost investment into soma and estimate mutation rate and competitive fitness of the resulting offspring using Caenorhabditis elegans nematodes. Second, I will employ experimental evolution in nematodes to assess the long-term - evolutionary costs of increased germline maintenance. Third, I will use germline transplantation in zebrafish Dario rerio to directly test whether germline proliferation reduces investment into soma in a vertebrate. Understanding how increased - investment into the soma damages the germline and reduces offspring fitness will provide a major advance in our understanding of ageing evolution and will have serious implications for applied research programs aimed at harnessing the power of - germline signalling to postpone ageing. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - GermlineAgeingSoma - - - ERC-2016-COG - - - 724909 - - - - - UNIVERSIDAD DE ZARAGOZA - UNIVERSIDAD DE ZARAGOZA - - - EUR 2 483 136 - - - Catalytic Dual-Function Devices Against Cancer - - - EUR 2 483 136 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Despite intense research efforts in almost every branch of the natural sciences, cancer continues to be one of the leading causes of death worldwide. It is thus remarkable that little or no therapeutic use has been made of a - whole discipline, heterogeneous catalysis, which is noted for its specificity and for enabling chemical reactions in otherwise passive environments. At least in part, this could be attributed to practical difficulties: the selective delivery of a - catalyst to a tumour and the remote activation of its catalytic function only after it has reached its target are highly challenging objectives. Only recently, the necessary tools to overcome these problems seem within reach. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Spain - - - CADENCE - - - ERC-2016-ADG - - - 742684 - - - - - HELSINGIN YLIOPISTO - HELSINGIN YLIOPISTO - - - EUR 1 999 987 - - - Gene knock-up via 3’UTR targeting to treat Parkinson’s disease - - - EUR 1 999 987 - - - Finland - Finland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Parkinson’s disease (PD) affects 1% of elderly persons and is currently incurable. PD pathogenesis is driven, at least in part, by defects in proteostasis and mitochondrial function, leading to degeneration of dopaminergic - axons and neuronal death. Neurotrophic factors (NTFs) such as GDNF can protect and restore dopaminergic axons. However, attempts to deploy NTFs ectopically in therapy models, or to increase proteostasis and mitochondrial function, have met with only - limited success. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Finland - - - PD UpReg - - - ERC-2016-COG - - - 724922 - - - - - UNIVERSITETET I OSLO - UNIVERSITETET I OSLO - - - EUR 1 999 481,75 - - - The Missing Link of Episodic Memory Decline in Aging: The Role of Inefficient Systems Consolidation - - - EUR 1 999 481,75 - - - Norway - Norway - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Which brain mechanisms are responsible for the faith of the memories we make with age, whether they wither or stay, and in what form? Episodic memory function does decline with age. While this decline can have multiple causes, - research has focused almost entirely on encoding and retrieval processes, largely ignoring a third critical process– consolidation. The objective of AgeConsolidate is to provide this missing link, by combining novel experimental cognitive paradigms - with neuroimaging in a longitudinal large-scale attempt to directly test how age-related changes in consolidation processes in the brain impact episodic memory decline. The ambitious aims of the present proposal are two-fold: - - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Norway - - - AgeConsolidate - - - ERC-2016-COG - - - 725025 - - - - - UNIVERSITETET I OSLO - UNIVERSITETET I OSLO - - - EUR 2 499 961 - - - Scalable inference algorithms for Bayesian evolutionary epidemiology - - - EUR 2 499 961 - - - Norway - Norway - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Advances in sequencing technologies are currently providing an unprecedented opportunity to a detailed discovery of the mechanisms involved in the evolution and spread of microbes causing human infectious disease. - Simultaneously the developers of statistical methods face an enormous challenge to cope with the wealth of data brought by this opportunity. We have very recently demonstrated the ability of our advanced computational approaches to deliver - breakthroughs in understanding pathogen evolution and transmission in numerous highlight results published in Science, PNAS and top-ranking Nature journals. The rise of microbial Big Data gives a promise of a giant leap in making causal discoveries, - however, the existing statistical methods are neither able to cope with the size and complexity of the emerging data sets nor designed to answer the novel biological questions they enable. To fulfil the promise of giant leaps SCARABEE will leverage - scalable inference methods by a unique combination of machine learning algorithms and Bayesian statistical models for evolutionary epidemiology. We focus on central biological questions about adaptation, epistasis, genome evolution and transmission - of microbes causing infectious disease. The Big Data combined with the novel inference methods will make it possible to answer a multitude of important questions that remain currently intractable. Through our close collaboration with the leading - research centres in infectious disease epidemiology and genomics we expect the SCARABEE project to considerably advance understanding of the evolution and transmission of numerous pathogens that pose a major threat to human health, which will be - important for reducing their disease burden in the future. Large-scale biological data will be used to benchmark the developed methods, which will be made publicly available as free software packages to benefit the wide community of microbiologists - and infectious disease epidemiologists. - - 2022-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Norway - - - SCARABEE - - - ERC-2016-ADG - - - 742158 - - - - - THE UNIVERSITY OF SUSSEX - THE UNIVERSITY OF SUSSEX - - - EUR 1 999 390 - - - Violence Elites and Resilience in States Under Stress - - - EUR 1 999 390 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Political violence affects 2 billion citizens across the developing world. Conflict contributes to political decline, high corruption and poverty, poor social cohesion and low institutional trust. VERSUS represents a new - direction in political, geographic and empirical subnational studies of conflict and governance. It determines how violence erupts from political processes in varied environments and examines how common internal and external shocks create new - trajectories of governance, violence and potential for political resilience. It argues that political relationships between subnational elites and regimes incentivise political violence in developing states. Through a suite of multi-and-mixed methods - including power mapping, extensive elite interviews, Bayesian spatial models and dynamic network innovations, VERSUS creates multiple real-time measures of power distribution across select African, Middle Eastern and Asian states for widespread - research and policy use. It has five objectives: to advance a developing paradigm on subnational political architectures and environments over static institutionalism; to generate several measures of comparative political power distributions in - developing states that capture the degree and depth of regime and elite relationships; to design and test scenarios to explain how, when and where violence erupts as a strategic function of architectures and environments; to develop and implement - novel conflict ‘resilience’ tests of regimes, elites and vulnerable members of society in response to internal and external shocks. This creates a state’s ‘carrying capacity’ for shocks and violence; and finally, to collaborate with development - practitioners and civil society to implement new standards for elite transparency, support for human rights and ‘good governance’ outcomes. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - VERSUS - - - ERC-2016-COG - - - 726504 - - - - - UNIVERSITETET I OSLO - UNIVERSITETET I OSLO - - - EUR 1 990 213 - - - Abiota, Biota, Constraints in Macroevolutionary Processes - - - EUR 1 990 213 - - - Norway - Norway - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - To what degree do microevolutionary processes that happen on a generational time scale matter for macroevolutionary patterns recorded on time scales of millions of years in the fossil record? To answer this fundamental - question in evolutionary biology, we need a model system in which we can overcome the conceptual and empirical boundaries imposed by disparate timescales. macroevolution.abc will develop bryozoans as the Drosophila of macroevolution, integrating - molecular, fossil, phenotypic, ecological and environmental data to shed light on the currently inaccessible “Dark Time Scale” (thousands, to tens of thousands of years), spanning the chasm between microevolution studied by population geneticists and - evolutionary ecologists and macroevolution studied by paleontologists and comparative phylogeneticists. Using bryozoans, a little-known but uniquely ideal study group for evolutionary questions, I will generate, then cross-integrate, (i) empirical - time series of intra- and interspecific biotic interactions; (ii) phenotypic data describing variation within genetic individuals, variation among contemporaneous individuals in both extinct and living populations; (iii) robust estimates of abundance - shifts in fossil populations; and (iv) speciation and extinction rate estimates from molecular phylogenies and the fossil record. The new bryozoan model evolutionary system will provide answers to previously intractable questions such as “do - ecological interactions crucial for individual survival matter for group diversification patterns observed on geological time scales” and “why do we have to wait a million years for bursts of phenotypic change”? - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Norway - - - macroevolution.abc - - - ERC-2016-COG - - - 724324 - - - - - NATIONAL UNIVERSITY OF IRELAND GALWAY - NATIONAL UNIVERSITY OF IRELAND GALWAY - - - EUR 149 954 - - - Challenging Hypertension Through Novel Medical Device Development - - - EUR 149 954 - - - Ireland - Ireland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Hypertension directly causes approximately 25% of heart attacks in Europe and, in its progressed form of cardiovascular disease, it is estimated to cause 42% of all deaths across Europe annually. Untreated hypertension is one - of the primary contributors to a number of the medical conditions with the greatest burden of care, including stroke, dementia and kidney failure. One of the most promising avenues for the treatment of hypertension has been research into primary - aldosteronism (PA). In the last ten years, PA has been recognised as the most common curable cause of hypertension. PA is thought to account for up to 18% of all cases of hypertension within the population and is caused by benign shallow adenomas on - the surface of the adrenal gland. Researchers have identified the effective treatment of PA as a clear mechanism to address Europe’s hypertension problem. However, finding an effective surgical or pharmaceutical treatment for PA has been challenging - to date. - - - 2018-12-31, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Ireland - - - REALTA - - - ERC-2016-PoC - - - 754308 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - THE UNIVERSITY OF SUSSEX - - - EUR 1 347 992 - - - Screening for cancer in the post-genomic era: diagnostic innovation and biomedicalisation in comparative perspective - - - EUR 1 347 992 - - - United Kingdom - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Cancer screening and the diagnostics industry: a comparative analysis of the political economy of diagnostic innovation. - - 2021-09-30, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - CANCERSCREEN - - - ERC-2016-STG - - - 716689 - - - - - THE UNIVERSITY OF SUSSEX - THE UNIVERSITY OF SUSSEX - - - EUR 1 979 270 - - - Time-Resolved Nonlinear Ghost Imaging - - - EUR 1 979 270 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project addresses major challenges in Terahertz (THz) sensing at the forefront of the experimental and theoretical investigation. The results will have far-reaching implications in complex science. They will target the - next generation of THz imagers, acknowledged as unique diagnostic tools in cross-disciplinary fields in light of the THz’s distinctive ability to unambiguously discriminate molecular compounds. - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - TIMING - - - ERC-2016-COG - - - 725046 - - - - - UNIVERSITA CA' FOSCARI VENEZIA - UNIVERSITA CA' FOSCARI VENEZIA - EESTI KIRJANDUSMUUSEUM - - - EUR 1 496 675 - - - Ethnobotany of divided generations in the context of centralization - - - EUR 1 496 675 - - - Italy - Italy - Estonia - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - Understanding the logics of obtaining, managing and perceiving of local natural resources, particularly plants, is crucial for ensuring sustainability of human life, as the use of plants is a key for survival of humans. The - proposed research will create an advanced understanding of the mechanisms of changes in ethnobotanical knowledge experienced by traditional societies/minor ethnic groups when dominating group try to unify and/or erode this practical knowledge. It - will also evaluate the effects of the sudden cease to existence of such centralization and following impact of the trial of revival of discontinued traditional etnobotanical knowledge. Research will evaluate the effect of several social and cultural - factors on the evolution of ethnobotanical knowledge of four compact, but divided ethnic minorities that had experienced for shorter (25 years) or longer (70 years) period different influences affecting their plant use and very different social - conditions (including welfare and economy). As a long-term outcome, based on the result of present and consequent studies scientists will be able to predict the extent and depth of the changes occurring in the ethnobotanical knowledge and as a - applied outcome learn to direct and educate people in the way that the knowledge necessary for sustainable maintenance and utilization of local plant resources will be constantly evolving in the way supporting health and well-being of different - populations. - - 2022-07-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Italy - - - DiGe - - - ERC-2016-STG - - - 714874 - - - - - UNIVERSITY OF CENTRAL LANCASHIRE - UNIVERSITY OF CENTRAL LANCASHIRE - DOLPHIO TECHNOLOGIES INFORMATIKAI KORLATOLT FELELOSSEGU TARSASAG - - - EUR 149 723 - - - Multilingual work spaces for sign language users – An online portal driving social innovation - - - EUR 149 723 - - - United Kingdom - United Kingdom - Hungary - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - This project aims to pilot a social innovation by translating some of the findings of the ERC-funded MULTISIGN project (“Multilingual behaviours in sign language users”) into an online portal which promotes and facilitates - transnational communication by deaf people through sign languages. The portal provides activities to users that increase their meta-linguistic awareness about the bi- and multilingual use of sign languages. Specifically, we will exploit research data - and analyses by translating them into a resource with educational units that support upskilling of deaf people in order to communicate remotely with signers of other sign languages. The MULTSIGN project had demonstrated that sign language users have - a unique enhanced potential, compared to spoken languages, to communicate across language boundaries, and the project will enable signers to exploit this potential. The portal also provides a service for setting up flexibly adaptable bi- and - multilingual online work spaces for transnational groups of sign language users, with an integrated tool for sign-to-sign-translation between different sign languages. This will enable disadvantaged deaf communities, who are largely isolated from - international contact, to access developments and resources already available elsewhere among international deaf communities but not linguistically accessible. The project is a collaboration between an academic partner, the University of Central - Lancashire (UCLan) in the UK and a private company with special expertise in the relevant area, Dolphio Technologies, in Hungary. Our joint team will develop the design and test the technical infrastructure for the project. We will conduct - demonstration, training and piloting workshops in several countries, and develop a business plan for further development and sustainability of the portal based on its marketable potential. - - 2018-09-30, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - SIGNSPACE - - - ERC-2016-PoC - - - 737587 - - - - - CINECA CONSORZIO INTERUNIVERSITARIO - THE UNIVERSITY OF EDINBURGH - BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION - UNIVERSITAET STUTTGART - SURFSARA BV - CSC-TIETEEN TIETOTEKNIIKAN KESKUS OY - ETHNIKO DIKTYO EREVNAS TECHNOLOGIAS AE - KUNGLIGA TEKNISKA HOEGSKOLAN - NATIONAL UNIVERSITY OF IRELAND GALWAY - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 9 206 161,50 - - - Transnational Access Programme for a Pan-European Network of HPC Research Infrastructures and Laboratories for scientific computing - - - EUR 9 216 248,59 - - - Italy - United Kingdom - Spain - Germany - Netherlands - Finland - Greece - Sweden - Ireland - France - - - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - HPC-Europa3 aims at maintaining the persistency of a high quality service of transnational access to the most advanced HPC infrastructures available in Europe for the European research science community. European researchers - could rely on the existence of such transnational access activity for almost two decades, and the main aim of this new innovative 3rd edition of HPC-Europa series is to fill the gap left in the four years since the end of the last initiative has - ended. - - - 2021-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.2."> - - - INFRAIA-01-2016-2017 - Integrating Activities for Advanced Communities - - - RIA - Research and Innovation action - - - Italy - - - HPC-EUROPA3 - - - H2020-INFRAIA-2016-1 - - - 730897 - - - - - KATHOLIEKE UNIVERSITEIT LEUVEN - TARKI Tarsadalomkutatasi Intezet Zrt - UNIVERSITEIT VAN AMSTERDAM - STOCKHOLMS UNIVERSITET - UNIVERSITAT TRIER - CENTRE D ESTUDIS DEMOGRAFICS - LISER - LUXEMBOURG INSTITUTE OF SOCIO-ECONOMIC RESEARCH - UNIVERSITEIT ANTWERPEN - UNIVERSITY OF ESSEX - DEUTSCHES INSTITUT FUR WIRTSCHAFTSFORSCHUNG DIW (INSTITUT FUR KONJUNKTURFORSCHUNG) EV - CONSERVATOIRE NATIONAL DES ARTS ET METIERS - CENTRE FOR EUROPEAN POLICY STUDIES - UNIVERSITA DI PISA - UNIVERSITY OF SOUTHAMPTON - Luxembourg Income Study, asbl - THE UNIVERSITY OF MANCHESTER - STREDOEUROPSKY INSTITUT PRE VYSKUMPRACE ZDRUZENIE - PANTEIO PANEPISTIMIO KOINONIKON KAIPOLITIKON EPISTIMON - CENTRALNY INSTYTUT OCHRONY PRACY - PANSTWOWY INSTYTUT BADAWCZY - - - EUR 9 345 420,50 - - - Integrating Research Infrastructure for European expertise on Inclusive Growth from data to policy - - - EUR 9 345 420,50 - - - Belgium - Hungary - Netherlands - Sweden - Germany - Spain - Luxembourg - Belgium - United Kingdom - Germany - France - Belgium - Italy - United Kingdom - Luxembourg - United Kingdom - Slovakia - Greece - Poland - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Other - Higher or Secondary Education Establishments - Research Organisations - - Referring to the increasingly challenging EU2020-ambitions of Inclusive Growth , the objectives of the InGRID-2 project are to advance the integration and innovation of distributed social sciences research infrastructures (RI) - on ‘povety, living conditions and social policies’ as well as ‘working conditions, vulnerability and labour policies’. InGRID-2 will extend transnational on-site and virtual access, organize mutual learning and discussions of innovations, and improve - data services and facilities of comparative research. The focus areas are a) integrated and harmonized data, (b) links between policy and practice, and (c) indicator-building tools. - - 2021-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.2."> - - - INFRAIA-01-2016-2017 - Integrating Activities for Advanced Communities - - - RIA - Research and Innovation action - - - Belgium - - - InGRID-2 - - - H2020-INFRAIA-2016-1 - - - 730998 - - - - - UNIVERSITAET ZU KOELN - UNIVERSITAET ZU KOELN - - - EUR 2 406 250 - - - Majorana Fermions in Topological Insulator Platforms - - - EUR 2 406 250 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Majorana fermions were recently discovered in topological superconductors as exotic quasiparticles having the curious property of being their own antiparticles. They are not only interesting as novel relativistic - quasiparticles, but are also useful for realizing fault-tolerant quantum computers. However, currently available platforms to materialize Majorana fermions are limited, and the existing platforms have respective drawbacks for actually building qubits - for a scalable quantum computer. Also, various unusual properties are predicted for Majorana fermions, but few have been experimentally addressed. To make a leap in the Majorana-fermion research which is technically highly demanding, one needs to - grow state-of-the-art materials and tightly combine them with mesoscopic device research. By performing such an integrated research efforts in the same laboratory, this project aims to explore new platforms for Majorana qubits and to establish new - methodologies to address peculiar physics of Majorana fermions. As new platforms, we pursue (i) three-dimensional topological-insulator nanoribbons and (ii) ferromagnetic topological-insulator thin films, both of which will be proximity-coupled to an - s-wave superconductor. Each of them allows for conceiving Majorana qubits based on different principles, which will be tested in this project. Also, by developing new methodologies, we will elucidate (i) non-Abelian statistics probed by - interferometry and (ii) quantized/universal heat transport phenomena probed by thermal conductance. These works will be complemented by materials growth efforts involving molecular beam epitaxy and detailed characterizations of the local electronic - states using scanning tunnelling spectroscopy. If successful, this project will not only contribute to the realization of scalable quantum computers, but also elucidate the non-Abelian statistics, which is a fundamentally new property of particles - and is ground breaking in physics. - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - MajoranaTopIn - - - ERC-2016-ADG - - - 741121 - - - - - INSTRUCT ACADEMIC SERVICES LIMITED - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - VIB - Masarykova univerzita - JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN - AARHUS UNIVERSITET - ETHNIKO IDRYMA EREVNON - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - OULUN YLIOPISTO - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - WEIZMANN INSTITUTE OF SCIENCE - CONSORZIO INTERUNIVERSITARIO RISONANZE MAGNETICHE DI METALLO PROTEINE - UNIVERSITEIT UTRECHT - UNIVERSIDADE NOVA DE LISBOA - INSTITUTO DE TECNOLOGIA QUIMICA E BIOLOGICA - UNIVERSIDADE NOVA DE LISBOA - KAROLINSKA INSTITUTET - CHEMICKY USTAV SLOVENSKEJ AKADEMIEVIED - - - EUR 3 950 000 - - - Releasing the full potential of Instruct to expand and consolidate infrastructure services for integrated structural life science research - - - EUR 3 950 000 - - - United Kingdom - United Kingdom - Belgium - Czech Republic - Germany - Denmark - Greece - Spain - Finland - France - Israel - Italy - Netherlands - Portugal - Portugal - Sweden - Slovakia - - - Other - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - Instruct-Ultra aims to advance the scope and efficiency of implementation of Instruct and consolidate the foundations for long-term sustainability. This will be achieved through specific objectives: expand Instruct membership - to new Member States and increase global links; engage new user communities; improve efficiencies in service delivery; improve data capture and management; adjust the scale and reliability of the infrastructure. Instruct-Ultra will deliver these - alongside the transition to ERIC legal status and rapid developments in, and increased demand for, integrated structural biology infrastructure. These advances in the scale and speed of delivery will earn further trust within the life science - community. One focus will to expand membership to Eastern European states and EFTA countries, integrating their structural biology communities into Instruct and providing new opportunities to support research excellence and raise standards. - Opportunities for engaging with industrialised and developing countries outside the ERA will build on existing cooperative work between Instruct and Asian, African and South American countries to establish strong bilateral programmes of benefit to - both parties, giving Instruct better engagement in emerging global challenges and positioning Instruct as a trusted global resource for high quality structural biology services. Starting from baseline operations four years ago Instruct has now - identified key areas of service which should be expanded, new potential user groups, and opportunities for more reliable, efficient and sometimes remotely used workflows. Instruct-Ultra will therefore test new modes of access and pilot new service - methods in high demand areas to accelerate access for more users. Instruct-Ultra will reinforce Instruct operations by updating and expanding the business plan and structural biology roadmap, whilst improving the interface with academia and industry - as a strategy to sustainability. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-03-2016-2017 - Individual support to ESFRI and other world-class research infrastructures - - - CSA - Coordination and support action - - - United Kingdom - - - INSTRUCT-ULTRA - - - H2020-INFRADEV-2016-1 - - - 731005 - - - - - THE UNIVERSITY OF SUSSEX - THE UNIVERSITY OF SUSSEX - - - EUR 149 903 - - - Design of a new non-existing layer of information delivery through smell - - - EUR 149 903 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The idea for this proposal is to demonstrate the design of olfactory widgets (OWidgets) as a proof-of-concept implementation based on the semantic integration of smell to convey specific information to the user. We will - showcase the meaningful design of OWidgets in two distinct markets. Widgets are well established as simple application extensions, integrated in a larger application and usually pre-installed on a device. Widgets allow quick access to information - without requiring a user to open the application that manages this information. OWidgets will expand the existing range of widgets and provide users with a new non-existing layer of information delivery through smell, and consequently allow the - creation of novel experiences in various application contexts. - - 2018-01-31, closed project - - - 2017-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - OWidgets - - - ERC-2016-PoC - - - 737576 - - - - - ISTITUTO NAZIONALE DI ASTROFISICA - ISTITUTO NAZIONALE DI ASTROFISICA - UNIVERSITAET HAMBURG - ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA - - - EUR 1 496 250 - - - Deciphering RAdio NOn-thermal Emission on the Largest scales - - - EUR 1 496 250 - - - Italy - Italy - Germany - Italy - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This proposal aims to understand the origin of the radio emission detected in the most massive objects in our Universe: galaxy clusters. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Italy - - - DRANOEL - - - ERC-2016-STG - - - 714245 - - - - - INSTITUTO DE MEDICINA MOLECULAR - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE UNIVERSITY OF SUSSEX - WEIZMANN INSTITUTE OF SCIENCE - FONDAZIONE TELETHON - INSTITUTUL DE BIOCHIMIE - Lipotype GmbH - GENOMED, DIAGNOSTICOS DE MEDICINA MOLECULAR SA - PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE - UNIVERSIDAD DE BUENOS AIRES - THE CHILDREN'S HOSPITAL OF PHILADELPHIA NON PROFIT ORG - - - EUR 1 102 500 - - - Genetic and Small Molecule Modifiers of Lysosomal Function - - - EUR 1 156 500 - - - Portugal - United Kingdom - United Kingdom - Israel - Italy - Romania - Germany - Portugal - Chile - Argentina - United States - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - - LysoMod will innovate in the area of personalized medicine for disorders linked to lysosomal dysfunction. This will be achieved by implementing a collaborative staff-exchange program between highly complementary and - multidisciplinary academic and non-academic partners with expertise in pharmacology, medicinal chemistry, cell biology, biochemistry, mouse and human genetics, transcriptomics, proteomics and lipidomics. Based on the critical role that lysosomes play - in cells, a better understanding of lysosomal function will have a major impact on human health, fostering the development of new strategies to improve quality of life for people affected by a variety of diseases, ranging from lysosomal storage - diseases (LSDs) to age-related neurodegenerative disorders. LysoMod’s specific objectives are: 1) to develop and further optimize existing therapies for LSDs; 2) to identify new targets for personalized therapies for LSDs; and 3) to investigate the - cross-talk between lysosomal function, signalling pathways and gene expression regulation. The pioneer work of a participant in the consortium led to the development of a drug that is approved for clinical use. LysoMod will i) investigate the - mechanisms of action of this and other drugs in lysosome-related disorder; ii) identify modifier genes involved in LSD pathology and test their potential as new targets for personalized therapeutic approaches; iii) identify candidate RNAs that can be - targeted to enhance lysosomal function. The companies in the consortium will ensure a rapid transfer of new knowledge into applications for diagnostics and clinical trials. Prioritising lysosomal dysfunction as a highly relevant biomedical problem, - the LysoMod consortium will implement a mentored staff-exchange program to provide young researchers with high-level training in innovative approaches for exploring biological systems, preparing the next generation of researchers for careers either - in the private or public health sectors. - - 2021-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Portugal - - - LysoMod - - - H2020-MSCA-RISE-2016 - - - 734825 - - - - - LUNDS UNIVERSITET - THE UNIVERSITY OF SHEFFIELD - KOBENHAVNS UNIVERSITET - OULUN YLIOPISTO - AARHUS UNIVERSITET - CLU srl - ALFRED-WEGENER-INSTITUT HELMHOLTZ-ZENTRUM FUR POLAR- UND MEERESFORSCHUNG - NORSK POLARINSTITUTT - NATURAL ENVIRONMENT RESEARCH COUNCIL - State Educational Institution of Higher Professional Education TOMSK STATE UNIVERSITY - JIHOCESKA UNIVERZITA V CESKYCH BUDEJOVICICH - POLARFORSKNINGSSEKRETARIETET - NIBIO - NORSK INSTITUTT FOR BIOOKONOMI - STOCKHOLMS UNIVERSITET - HELSINGIN YLIOPISTO - GRONLANDS NATURINSTITUT - Instytut Geofizyki Polskiej Akademii Nauk - TURUN YLIOPISTO - UNIVERSITETET I OSLO - LUONNONVARAKESKUS - INSITUTE FOR BIOLOGICAL PROBLEMS OF CRYOLITHOZONE SIBERIAN BRANCH RUSSIAN ACADEMY OF SCIENCES - M.V. LOMONOSOV MOSCOW STATE UNIVERSITY - SVERIGES LANTBRUKSUNIVERSITET - ZENTRALANSTALT FUR METEOROLOGIE UNDGEODYNAMIK - UNIVERSITAET INNSBRUCK - YUGRA STATE UNIVERSITY - JARDFEINGI - RANNSOKNARSTODIN RIF - UNIVERSITE LAVAL - INSTYTUT GEOGRAFII I PRZESTRZENNEGO ZAGOSPODAROWANIA IM STANISLAWA LESZCZYCKIEGO POLSKIEJ AKADEMII NAUK - CONSIGLIO NAZIONALE DELLE RICERCHE - University of Alaska - SUDURNES SCIENCE AND LEARNING CENTER - ILMATIETEEN LAITOS - CAFF SKRIFSTOFAN A ISLANDI - UNIVERSITETET I TROMSOE - AURORA COLLEGE - THE ARTIC INSTITUTE OF NORTH AMERICA - UMBILICAL DESIGN AB - AF TECHNOLOGY AB - METEOROLOGISK INSTITUTT - LANDBUNADARHASKOLI ISLANDS - RIJKSUNIVERSITEIT GRONINGEN - INTERNATIONAL POLAR FOUNDATION - MAPILLARY AB - University Centre in Svalbard - - - EUR 10 000 000 - - - International Network for Terrestrial Research and Monitoring in the Arctic - - - EUR 10 000 000 - - - Sweden - United Kingdom - Denmark - Finland - Denmark - Italy - Germany - Norway - United Kingdom - Russia - Czech Republic - Sweden - Norway - Sweden - Finland - Greenland - Poland - Finland - Norway - Finland - Russia - Russia - Sweden - Austria - Austria - Russia - Faeroe Islands - Iceland - Canada - Poland - Italy - United States - Iceland - Finland - Iceland - Norway - Canada - Canada - Sweden - Sweden - Norway - Iceland - Netherlands - Belgium - Sweden - Norway - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Other - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Other - Research Organisations - Other - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - INTERACT aims for a geographically comprehensive and excellent state-of-the-art terrestrial research infrastructure throughout the Arctic and adjoining forest and alpine regions to identify environmental change, to facilitate - understanding and prediction of future change and to inform decision makers about societally-relevant impacts. INTERACT is the fundamental building block and one-stop-shop for EU and international projects, programmes and organisations requiring - access to northern lands, data and services, and includes a rapid response capability to potential hazards. INTERACT is pan-Arctic, multidisciplinary and crosses EU call domains by linking to forest, coastal, marine and atmospheric communities. - - - 2020-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.2."> - - - INFRAIA-01-2016-2017 - Integrating Activities for Advanced Communities - - - RIA - Research and Innovation action - - - Sweden - - - INTERACT - - - H2020-INFRAIA-2016-1 - - - 730938 - - - - - ILMATIETEEN LAITOS - HELSINGIN YLIOPISTO - CONSIGLIO NAZIONALE DELLE RICERCHE - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - NATIONAL INSTITUTE OF RESEARCH AND DEVELOPMENT FOR OPTOELECTRONICS - CESKY HYDROMETEOROLOGICKY USTAV - LEIBNIZ INSTITUT FUER TROPOSPHAERENFORSCHUNG e.V. - KARLSRUHER INSTITUT FUER TECHNOLOGIE - NATIONAL OBSERVATORY OF ATHENS - NORSK INSTITUTT FOR LUFTFORSKNING STIFTELSE - UNIVERSITAT POLITECNICA DE CATALUNYA - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - UNIVERSIDAD DE VALLADOLID - THE UNIVERSITY OF MANCHESTER - NATURAL ENVIRONMENT RESEARCH COUNCIL - SCIENCE AND TECHNOLOGY FACILITIES COUNCIL - KONINKLIJK NEDERLANDS METEOROLOGISCH INSTITUUT-KNMI - PAUL SCHERRER INSTITUT - EIDGENOSSISCHE MATERIALPRUFUNGS- UND FORSCHUNGSANSTALT - THE CYPRUS INSTITUTE - Instytut Geofizyki Polskiej Akademii Nauk - LUNDS UNIVERSITET - INSTITUT ROYAL D'AERONOMIE SPATIALEDE BELGIQUE - NATIONAL UNIVERSITY OF IRELAND GALWAY - EESTI MAAULIKOOL - AARHUS UNIVERSITET - INSTITUTE OF NUCLEAR RESEARCH AND NUCLEAR ENERGY - BULGARIAN ACADEMY OF SCIENCES - JRC -JOINT RESEARCH CENTRE- EUROPEAN COMMISSION - - - EUR 3 999 996,25 - - - ACTRIS PPP - Aerosols, Clouds and Trace gases Preparatory Phase Project - - - EUR 3 999 996,25 - - - Finland - Finland - Italy - France - Romania - Czech Republic - Germany - Germany - Greece - Norway - Spain - Spain - Spain - United Kingdom - United Kingdom - United Kingdom - Netherlands - Switzerland - Switzerland - Cyprus - Poland - Sweden - Belgium - Ireland - Estonia - Denmark - Bulgaria - Belgium - - - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Other - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - The Research Infrastructure (RI) ACTRIS – Aerosols, Clouds and Trace Gases - is the pan-European RI that consolidates activities amongst European partners for observations of aerosols, clouds, and trace gases and for - understanding of the related atmospheric processes, to provide RI services to wide user groups. - - - 2019-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-02-2016 - Preparatory Phase and support to early phase of ESFRI projects - - - CSA - Coordination and support action - - - Finland - - - ACTRIS PPP - - - H2020-INFRADEV-2016-2 - - - 739530 - - - - - UNIVERSITE DE FRANCHE-COMTE - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON - CONSORZIO INTERUNIVERSITARIO NAZIONALE PER LA SCIENZA E TECNOLOGIA DEI MATERIALI - INSTITUT POLYTECHNIQUE DE GRENOBLE - UNIVERSITAET ZU KOELN - CEDRAT TECHNOLOGIES SA - AIXTRON SE - STMICROELECTRONICS SRL - - - EUR 3 382 787,16 - - - Piezoelectric Energy Harvesters for Self-Powered Automotive Sensors: from Advanced Lead-Free Materials to Smart Systems - - - EUR 3 382 787,16 - - - France - United Kingdom - France - Italy - France - Germany - France - Germany - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - "The proposed Initial Training Network entitled ""Piezoelectric Energy Harvesters for Self-Powered Automotive Sensors: from Advanced Lead-Free Materials to Smart Systems (ENHANCE)"" will provide Early Stage Researchers (ESRs) - with broad and intensive training within a multidisciplinary research and teaching environment. Key training topics will include development of energy harvesters compatible with MEMS technology and able to power wireless sensor. Applied to - automobiles, such technology will allow for 50 kg of weight saving, connection simplification, space reduction, and reduced maintenance costs - all major steps towards creating green vehicles. Other important topics include technology innovation, - education and intellectual asset management. - - 2021-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - France - - - ENHANCE - - - H2020-MSCA-ITN-2016 - - - 722496 - - - - - THE UNIVERSITY OF SHEFFIELD - MAKEA INDUSTRIES GMBH - HELSINGIN YLIOPISTO - INSTITUTUL DE SOCIOLOGIE - UNIVERSITETET I OSLO - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - AARHUS UNIVERSITET - KOBENHAVNS UNIVERSITET - HASKOLI ISLANDS - HASKOLINN A AKUREYRI - MAKERS PARTNERSHIP - ASOCIATIA HATCH ATELIER - RG MENNTARADGJOF SLF - ARHUS KOMMUNE - - - EUR 531 000 - - - MAKERSPACES IN THE EARLY YEARS: ENHANCING DIGITAL LITERACY AND CREATIVITY (MakEY) - - - EUR 549 000 - - - United Kingdom - Germany - Finland - Romania - Norway - United Kingdom - Denmark - Denmark - Iceland - Iceland - United Kingdom - Romania - Iceland - Denmark - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - This two-year project involves an international and inter-sector research and training network that focuses on the potential of makerspaces, which are specific spaces that enable creative design and the production of both - digital and non-digital artefacts, to foster the digital literacy and creative skills of young children. A key aim of the project is to inform educational policy and practice in this area, enabling formal learning institutions (early years settings - and primary schools) to learn from practice in non-formal learning spaces, and vice-versa, and also to foster innovation and entrepreneurship in the makerspace sector, enabling SMEs to develop robust business models and appropriate resources for - future work in this area. The project involves 16 academic and non-academic beneficiaries and 10 non-academic, non-beneficiary partners across 6 EU countries (Denmark, Finland, Iceland, Norway, Romania, UK), an Associated Country (Colombia) and 4 - Third Countries (Australia, Canada, South Africa and USA). This global network of university scholars, cultural industry partners in makerspaces, early years practitioners, museum educators and librarians will engage in a collaborative research and - training programme that addresses 4 objectives, which are to: - - 2019-06-30, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - United Kingdom - - - MakEY - - - H2020-MSCA-RISE-2016 - - - 734720 - - - - - RELAIS CULTURE EUROPE ASSOCIATION - UNIVERSITAT DE VALENCIA - UDRUZENJE ZA KULTURU I UMJETNOST CRVENA - BUNKER ZAVOD ZA ORGANIZACIJO IN IZVEDBO, KULTURNIH PRIREDITEV - ZNANSTVENORAZISKOVALNI CENTER SLOVENSKE AKADEMIJE ZNANOSTI IN UMETNOSTI - INSTITUT ZA KRIMINOLOGIJO PRI PRAVNI FAKULTETI V LJUBLJANI - BEDEN ISLEMSEL SANATLAR DERNEGI - IZMIR EKONOMI UNIVERSITESI - ISTANBUL TEKNIK UNIVERSITESI - FUNDACJA TEREN OTWARTY - UNIVERSITY COLLEGE LONDON - UNIVERSITA DEGLI STUDI DI PERUGIA - ASSOCIAZIONE CITTA EUROPEA DEI MESTIERI D'ARTE - GENERIQUES ASSOCIATION - FORUM TUNISIEN POUR LES DROITS ECONOMIQUES ET SOCIAUX - - - EUR 1 858 500 - - - Art / culture / economy to democratize society. Research in placemaking for alternative narratives - - - EUR 1 858 500 - - - France - Spain - Bosnia and Herzegovina - Slovenia - Slovenia - Slovenia - Turkey - Turkey - Turkey - Poland - United Kingdom - Italy - Italy - France - Tunisia - - - Other - Higher or Secondary Education Establishments - Other - Other - Higher or Secondary Education Establishments - Research Organisations - Other - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - Other - Other - - The project trans-making aims to establish a multilateral network of research and innovation staff active in the fields of placemaking/place-based art activities as a space to create alternative narratives for social, economic and democratic renewal. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - France - - - trans-making - - - H2020-MSCA-RISE-2016 - - - 734855 - - - - - UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK - THE EUROPEAN MARINE ENERGY CENTRE LIMITED - INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER - UNIVERSITY OF STRATHCLYDE - FUNDACION TECNALIA RESEARCH & INNOVATION - DANMARKS TEKNISKE UNIVERSITET - WAVEC/OFFSHORE RENEWABLES - CENTRO DE ENERGIA OFFSHORE ASSOCIACAO - AALBORG UNIVERSITET - OFFSHORE RENEWABLE ENERGY CATAPULT - FUNDACION INSTITUTO DE HIDRAULICA AMBIENTAL DE CANTABRIA - STICHTING TIDAL TESTING CENTRE - ECOLE CENTRALE DE NANTES - FUNDACAO EUROCEAN - SMARTBAY IRELAND - SINTEF ENERGI AS - THE UNIVERSITY OF EXETER - FUNDACION CENER-CIEMAT - CONSIGLIO NAZIONALE DELLE RICERCHE - FLOWAVE TT LIMITED - GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER - STICHTING MARITIEM RESEARCH INSTITUUT NEDERLAND - FUNDACION CENTRO TECNOLOGICO DE COMPONENTES - UNIVERSITA DEGLI STUDI DI FIRENZE - UNIVERSITY OF PLYMOUTH - CONSORCIO PARA EL DISENO, CONSTRUCCION, EQUIPAMIENTO Y EXPLOTACION DE LA PLATAFORMA OCEANICA DE CANARIAS - NATIONAL UNIVERSITY OF IRELAND GALWAY - ENTE VASCO DE LA ENERGIA - THE QUEEN'S UNIVERSITY OF BELFAST - NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU - UNIVERSITY OF SURREY - SSPA SWEDEN AB. - BISCAY MARINE ENERGY PLATFORM SA - MARIENE INFORMATIE SERVICE MARIS BV - CSC-TIETEEN TIETOTEKNIIKAN KESKUS OY - UPPSALA UNIVERSITET - OCEANIDE - UNIVERSITY OF LIMERICK - THE UNIVERSITY OF EDINBURGH - EUROPEAN OCEANENERGY ASSOCIATION EU OEA - - - EUR 10 592 285,23 - - - Marine Renewable Infrastructure Network for Enhancing Technologies 2 - - - EUR 10 592 285,23 - - - Ireland - United Kingdom - France - United Kingdom - Spain - Denmark - Portugal - Denmark - United Kingdom - Spain - Netherlands - France - Portugal - Ireland - Norway - United Kingdom - Spain - Italy - United Kingdom - Germany - Netherlands - Spain - Italy - United Kingdom - Spain - Ireland - Spain - United Kingdom - Norway - United Kingdom - Sweden - Spain - Netherlands - Finland - Sweden - France - Ireland - United Kingdom - Belgium - - - Higher or Secondary Education Establishments - Other - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Other - Other - Higher or Secondary Education Establishments - Other - Other - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - - Integrating activities planned under MaRINET 2 build upon the achievements of the advanced community created in MaRINET FP7. MaRINET 2 will ensure the continued integration and enhancement of all leading European research - infrastructure and facilities specialising in research, development and testing of offshore renewable energy systems including electrical sub systems and grid integration through a range of TRLs (1-7). MaRINET FP7 proved the added value of uniting - these facilities, and substantially improving their capability as a community of practice to deliver consistent testing services ensuring, quantifiable, stepwise innovation and progress in the development of devices and key components, and - identifying critical areas for further technical investigation and enhancement. Whilst activities proposed under MaRINET 2 will follow the same formula, balancing networking/ joint research/ and transnational access, the consortium and scope of work - is expanded to include xx partners in xx countries with xx facilities. The e-infrastructure programme fills a strategic gap. Taking stock of existing capacities for data management/sharing; it addresses user requirements and demonstrates the - operation of a new system based on standards and tools adapted from the SeaDataNet infrastructure. The European Commission and member states recognise offshore renewable energy as an important source of clean energy that can: generate economic growth - and employment; increase energy security; and boost competitiveness and technological innovation. The realisation of this potential depends on the accelerated development, deployment and grid integration of reliable, efficient technologies for - harvesting offshore renewable energy, which in turn requires robust and exhaustive testing in dedicated facilities operated by practitioners with specialised expertise. MaRINET 2 provides this ecosystem, and is pre-eminently suited to fostering the - next generation of offshore renewable energy devices. - - 2021-06-30, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.2."> - - - INFRAIA-01-2016-2017 - Integrating Activities for Advanced Communities - - - RIA - Research and Innovation action - - - Ireland - - - MARINET2 - - - H2020-INFRAIA-2016-1 - - - 731084 - - - - - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH - EUROPEAN SPALLATION SOURCE ERIC - RHP TECHNOLOGY GMBH - ION BEAM APPLICATIONS SA - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - Société civile SYNCHROTRON SOLEIL - Bruker HTS GmbH - STIFTUNG DEUTSCHES ELEKTRONEN-SYNCHROTRON DESY - FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - GSI HELMHOLTZZENTRUM FUER SCHWERIONENFORSCHUNG Gmbh - HEIDELBERGER IONENSTRAHL THERAPIE (HIT) BETRIEBS GESELLSCHAFT AM UNIVERSITATSKLINIKUM HEIDELBERG MIT BESCHRANKTER HAFTUNG - HELMHOLTZ-ZENTRUM BERLIN FUR MATERIALIEN UND ENERGIE GMBH - JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN - JOHANNES GUTENBERG-UNIVERSITAT MAINZ - KARLSRUHER INSTITUT FUER TECHNOLOGIE - UNIVERSITAET SIEGEN - MAGYAR TUDOMANYOS AKADEMIA WIGNER FIZIKAI KUTATOKOZPONT - CONSIGLIO NAZIONALE INGEGNERI - ISTITUTO NAZIONALE DI FISICA NUCLEARE - POLITECNICO DI MILANO - POLITECNICO DI TORINO - RIGAS TEHNISKA UNIVERSITATE - UNIVERSITA TA MALTA - UNIVERSITEIT TWENTE - INSTYTUT CHEMII I TECHNIKI JADROWEJ - POLITECHNIKA WARSZAWSKA - ASSOCIACAO DO INSTITUTO SUPERIOR TECNICO PARA A INVESTIGACAO E DESENVOLVIMENTO - "INSTITUTUL NATIONAL DE CERCETARE -DEZVOLTARE PENTRU FIZICA SI INGINERIE NUCLEARA ""HORIA HULUBEI"" (IFIN-HH)" - Institute of Electrical Engineering, Slovak Academy of Sciences - COSYLAB LABORATORIJ ZA KONTROLNE SISTEME DD - CONSORCIO PARA LA CONSTRUCCION EQUIPAMIENTO Y EXPLOTACION DEL LABORATORIO DE LUZ SINCROTRON - CENTRO DE INVESTIGACIONES ENERGETICAS, MEDIOAMBIENTALES Y TECNOLOGICAS-CIEMAT - LUNDS UNIVERSITET - UPPSALA UNIVERSITET - PAUL SCHERRER INSTITUT - UNIVERSITE DE GENEVE - THE UNIVERSITY OF HUDDERSFIELD - SCIENCE AND TECHNOLOGY FACILITIES COUNCIL - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 10 000 000 - - - Accelerator Research and Innovation for European Science and Society - - - EUR 10 176 755,75 - - - Switzerland - Sweden - Austria - Belgium - France - France - France - Germany - Germany - Germany - Germany - Germany - Germany - Germany - Germany - Germany - Germany - Germany - Hungary - Italy - Italy - Italy - Italy - Latvia - Malta - Netherlands - Poland - Poland - Portugal - Romania - Slovakia - Slovenia - Spain - Spain - Sweden - Sweden - Switzerland - Switzerland - United Kingdom - United Kingdom - United Kingdom - - - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Denise Ogden - Tel.: +44-1484-473192 - Fax: +44-1484-472682 - Research Organisations - Higher or Secondary Education Establishments - - Particle accelerators are essential tools for delivering excellence in many scientific fields and are widely used in industrial, healthcare and other applications. The demand of pushing further their scientific reach and of - reinforcing their impact on society results in new challenges that must be addressed in the years to come: existing infrastructures are stretched to all performance frontiers, several world-class accelerator-based facilities on the ESFRI roadmap are - under construction, and strategic decisions are needed for future accelerator facilities, to be realised on a global scale. - - - 2021-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.2."> - - - INFRAIA-01-2016-2017 - Integrating Activities for Advanced Communities - - - RIA - Research and Innovation action - - - Switzerland - - - ARIES - - - H2020-INFRAIA-2016-1 - - - 730871 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - ISTITUTO NAZIONALE DI ASTROFISICA - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - SCIENCE AND TECHNOLOGY FACILITIES COUNCIL - EUROPEAN SOUTHERN OBSERVATORY - ESO EUROPEAN ORGANISATION FOR ASTRONOMICAL RESEARCH IN THE SOUTHERN HEMISPHERE - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - UNIVERSITEIT LEIDEN - FIRST LIGHT IMAGING SAS - OFFICE NATIONAL D'ETUDES ET DE RECHERCHES AEROSPATIALES - NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO - INSTITUTO DE ASTROFISICA DE CANARIAS - MAGYAR TUDOMANYOS AKADEMIA CSILLAGASZATI ES FOLDTUDOMANYI KUTATOKOZPONT - UNIWERSYTET WARSZAWSKI - NATIONAL OBSERVATORY OF ATHENS - NATIONAL UNIVERSITY OF IRELAND GALWAY - KOBENHAVNS UNIVERSITET - UNIVERSITE DE LIEGE - UNIVERSIDADE DO PORTO - LEIBNIZ-INSTITUT FUR ASTROPHYSIK POTSDAM (AIP) - POLITECNICO DI MILANO - NORDIC OPTICAL TELESCOPE SCIENTIFIC ASSOCIATION - DEPARTMENT OF INDUSTRY - HERIOT-WATT UNIVERSITY - THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS - LIVERPOOL JOHN MOORES UNIVERSITY - UNIVERSITY OF DURHAM - THE UNIVERSITY OF EXETER - UNIVERSITY OF BATH - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE UNIVERSITY OF SHEFFIELD - INSTITUT D'OPTIQUE THEORIQUE ET APPLIQUEE IOTA - SUPOPTIQUE - - - EUR 10 000 000 - - - Optical Infrared Coordination Network for Astronomy - - - EUR 10 011 619,61 - - - United Kingdom - France - Italy - Germany - United Kingdom - Germany - Spain - Netherlands - France - France - Netherlands - Spain - Hungary - Poland - Greece - Ireland - Denmark - Belgium - Portugal - Germany - Italy - Sweden - Australia - United Kingdom - United Kingdom - United Kingdom - United Kingdom - United Kingdom - United Kingdom - United Kingdom - United Kingdom - France - - - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Europe has become a global leader in optical-near infrared astronomy through excellence in space and ground-based experimental and theoretical research. While the major infrastructures are delivered through major national and - multi-national agencies (ESO, ESA) their continuing scientific competitiveness requires a strong community of scientists and technologists distributed across Europe’s nations. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.2."> - - - INFRAIA-01-2016-2017 - Integrating Activities for Advanced Communities - - - RIA - Research and Innovation action - - - United Kingdom - - - OPTICON - - - H2020-INFRAIA-2016-1 - - - 730890 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - STICHTING ASTRON, NETHERLANDS INSTITUTE FOR RADIO ASTRONOMY - INSTITUT DE RADIO ASTRONOMIE MILLIMETRIQUE SOCIETE CIVILE - ISTITUTO NAZIONALE DI ASTROFISICA - JOINT INSTITUTE FOR VERY LONG BASELINE INTERFEROMETRY AS A EUROPEAN RESEARCH INFRASTRUCTURE CONSORTIUM (JIV-ERIC) - THE UNIVERSITY OF MANCHESTER - CHALMERS TEKNISKA HOEGSKOLA AB - SCIENCE AND TECHNOLOGY FACILITIES COUNCIL - STICHTING SRON NETHERLANDS INSTITUTE FOR SPACE RESEARCH - OBSERVATOIRE DE PARIS - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - UNIVERSIDAD DE ALCALA - EUROPEAN SOUTHERN OBSERVATORY - ESO EUROPEAN ORGANISATION FOR ASTRONOMICAL RESEARCH IN THE SOUTHERN HEMISPHERE - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - RIJKSUNIVERSITEIT GRONINGEN - DUBLIN INSTITUTE FOR ADVANCED STUDIES - STICHTING INTERNATIONAL LOFAR TELESCOPE - UNIWERSYTET MIKOLAJA KOPERNIKA W TORUNIU - UNIVERSITAET ZU KOELN - VENTSPILS AUGSTSKOLA - AALTO-KORKEAKOULUSAATIO - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - KOREA ASTRONOMY AND SPACE SCIENCE INSTITUTE - TURUN YLIOPISTO - UNIVERSITE DE BORDEAUX - TECHNISCHE UNIVERSITEIT DELFT - UNIVERSITY OF GLASGOW - DEPARTMENT OF SCIENCE AND TECHNOLOGY - - - EUR 10 000 000 - - - Advanced Radio Astronomy in Europe - - - EUR 10 513 023,13 - - - Germany - Netherlands - France - Italy - Netherlands - United Kingdom - Sweden - United Kingdom - Netherlands - France - United Kingdom - Spain - Germany - Germany - Netherlands - Ireland - Netherlands - Poland - Germany - Latvia - Finland - Ireland - South Korea - Finland - France - Netherlands - United Kingdom - South Africa - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - RadioNet is a consortium of 28 institutions in Europe, Republic of Korea and South Africa, integrating at European level world-class infrastructures for research in radio astronomy. These include radio telescopes, telescope - arrays, data archives and the globally operating European Network for Very Long Baseline Interferometry (EVN). RadioNet is de facto widely regarded to represent the interests of radio astronomy in Europe. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.2."> - - - INFRAIA-01-2016-2017 - Integrating Activities for Advanced Communities - - - RIA - Research and Innovation action - - - Germany - - - RadioNet - - - H2020-INFRAIA-2016-1 - - - 730562 - - - - - ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSITE D'AVIGNON ET DES PAYS DE VAUCLUSE - UNIVERSIDAD COMPLUTENSE DE MADRID - CONSIGLIO NAZIONALE DELLE RICERCHE - ADSI-AUSTRIAN DRUG SCREENING INSTITUTE GMBH - PHARMAGNOSE VIOTECHNOLOGIKI ANONYMI ETAIREIA - UNI-PHARMA KLEON TSETIS, FARMAKEFTIKA ERGASTIRIA ANONYMOS VIOMICHANIKIKAI EMPORIKI - SERVIZO GALEGO DE SAUDE - NATAC BIOTECH SL - ALNUMED GMBH - NEURO-SYS - - - EUR 1 732 500 - - - Bioactive compounds from Olea europaea: investigation and application in food, cosmetic and pharmaceutical industry - - - EUR 1 732 500 - - - Greece - France - France - Spain - Italy - Austria - Greece - Greece - Spain - Spain - Germany - France - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The goal of Olive-Net project is to introduce a novel approach for the exploration, valorization and marketing of new products based on bioactive compounds from Olea europaea. This will be achieved through an extended and - well-balanced scheme of researcher’s secondments between universities and enterprises from EU & Associated countries as well as universities from Third countries. A mutual scientific project developed on the needs and interests of both sectors - exploiting the existing expertise will be the base of this proposal. Products and side-products of the olive tree such as olive oil, edible olive fruits, olive mill waste and olive tree leaves, will be subjected to a series of state-of-the-art - extraction and isolation cascades in order to provide extracts, enriched fractions and isolated compounds of high purity. Target chemical categories will involve the well known olive oil polyphenols and secoiridoids, that will be assessed for their - safety and pharmacological effects against inflammation, osteoarthritis, cardiovascular disease, etc. in cell-based and in vivo assays. All active ingredients will be identified and characterized with advanced analytical techniques, in order to be - integrated in formulations and products in the area of nutraceuticals/dietary supplements. Within this project, core scientific multidisciplinary knowledge from different research areas will be integrated creating valuable synergies. Expertise will - be transferred by means of the seconded researchers training in environments with different research orientation where complimentary skills are required. Special attention will be given to dissemination activities aiming to public awareness of - benefits of healthy diet(s). Olive-Net aspires to create a successful model promoting considerably researchers’ competences and long-lasting collaboration between Industry and Academia. - - 2021-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Greece - - - Olive-Net - - - H2020-MSCA-RISE-2016 - - - 734899 - - - - - UNIVERSITETET I OSLO - UNIVERSITETET I OSLO - - - EUR 1 476 948 - - - The Global and Local Organization of Production - - - EUR 1 476 948 - - - Norway - Norway - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - A defining feature of the global economy is the gradual fragmentation of production across firms and - - 2021-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Norway - - - GLOBALPROD - - - ERC-2016-STG - - - 715147 - - - - - UNIVERSITAET ZU KOELN - UNIVERSITAET ZU KOELN - - - EUR 1 489 916 - - - Social integration and boundary making in adolescence - - - EUR 1 489 916 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The idea of boundary making has moved to the centre of influential agendas in immigration research. While many studies show the location and meaning of ethnic boundaries to vary across contexts, the conditions under which - actors pursue different strategies of boundary making and produce different configurations of boundaries remain largely unknown. A major reason is the lack of a contextual unit of analysis that allows one to look at a large number of comparable - social fields in which processes of boundary making unfold. - - 2022-01-31, ongoing project - - - 2017-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - SOCIALBOND - - - ERC-2016-STG - - - 716461 - - - - - INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER - MARIENE INFORMATIE SERVICE MARIS BV - NATURAL ENVIRONMENT RESEARCH COUNCIL - BUNDESAMT FUR SEESCHIFFFAHRT UND HYDROGRAPHIE - SVERIGES METEOROLOGISKA OCH HYDROLOGISKA INSTITUT - INSTITUTO ESPANOL DE OCEANOGRAFIA - HELLENIC CENTRE FOR MARINE RESEARCH - ISTITUTO NAZIONALE DI OCEANOGRAFIA E DI GEOFISICA SPERIMENTALE - ALL-RUSSIAN RESEARCH INSTITUTE OF HYDROMETEOROLOGICAL INFORMATION-WORLD DATA CENTRE - AGENZIA NAZIONALE PER LE NUOVE TECNOLOGIE, L'ENERGIA E LO SVILUPPO ECONOMICO SOSTENIBILE - ISTITUTO NAZIONALE DI GEOFISICA E VULCANOLOGIA - MIDDLE EAST TECHNICAL UNIVERSITY - ALFRED-WEGENER-INSTITUT HELMHOLTZ-ZENTRUM FUR POLAR- UND MEERESFORSCHUNG - UNIVERSITE DE LIEGE - HAVFORSKNINGSINSTITUTTET - AARHUS UNIVERSITET - International Council for the Exploration of the Sea - JRC -JOINT RESEARCH CENTRE- EUROPEAN COMMISSION - MARINE INSTITUTE - INSTITUTO HIDROGRAFICO - STICHTING NIOZ, KONINKLIJK NEDERLANDS INSTITUUT VOOR ONDERZOEK DER ZEE - INSTITUT ROYAL DES SCIENCES NATURELLES DE BELGIQUE - VLAAMS INSTITUUT VOOR DE ZEE VZW - HAFRANNSOKNASTOFNUNIN - ILMATIETEEN LAITOS - INSTYTUT METEOROLOGII I GOSPODARKIWODNEJ - PANSTWOWY INSTYTUT BADAWCZY - TALLINNA TEHNIKAULIKOOL - LATVIJAS HIDROEKOLOGIJAS INSTITUTS - P.P. SHIRSHOV INSTITUTE OF OCEANOLOGY OF RUSSIAN ACADEMY OF SCIENCES - INSTITUTE OF OCEANOLOGY - BULGARIAN ACADEMY OF SCIENCES - INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE MARINA GRIGORE ANTIPA - IVANE JAVAKHISHVILI TBILISI STATE UNIVERSITY - Institute of Oceanography and Fisheries - NACIONALNI INSTITUT ZA BIOLOGIJO - UNIVERSITA TA MALTA - ISRAEL OCEANOGRAPHIC AND LIMNOLOGICAL RESEARCH LIMITED - CONSIGLIO NAZIONALE DELLE RICERCHE - INSTYTUT OCEANOLOGII POLSKIEJ AKADEMII NAUK - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - STICHTING DELTARES - SUOMEN YMPARISTOKESKUS - UKRAINIAN SCIENTIFIC CENTRE OF ECOLOGY OF THE SEA - ETT SPA - EUROGOOS - DEUTSCHES KLIMARECHENZENTRUM GMBH - CINECA CONSORZIO INTERUNIVERSITARIO - CSC-TIETEEN TIETOTEKNIIKAN KESKUS OY - SCIENCE AND TECHNOLOGY FACILITIES COUNCIL - ETHNIKO DIKTYO EREVNAS TECHNOLOGIAS AE - UNIVERSITETET I BERGEN - HELMHOLTZ ZENTRUM FUR OZEANFORSCHUNG KIEL - 52°North Initiative for Geospatial Open Source Software GmbH - SERVICE HYDROGRAPHIQUE ET OCEANOGRAPHIQUE DE LA MARINE - ORION - INSTITOUTO AEIFORIAS KAI ANAPTIKSEON - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA - - - EUR 9 999 737,50 - - - SeaDataCloud - Further developing the pan-European infrastructure for marine and ocean data management - - - EUR 9 999 737,50 - - - France - Netherlands - United Kingdom - Germany - Sweden - Spain - Greece - Italy - Russia - Italy - Italy - Turkey - Germany - Belgium - Norway - Denmark - Denmark - Belgium - Ireland - Portugal - Netherlands - Belgium - Belgium - Iceland - Finland - Poland - Estonia - Latvia - Russia - Bulgaria - Romania - Georgia - Croatia - Slovenia - Malta - Israel - Italy - Poland - Spain - Netherlands - Finland - Ukraine - Italy - Belgium - Germany - Italy - Finland - United Kingdom - Greece - Norway - Germany - Germany - France - Cyprus - France - Italy - - - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Research Organisations - Research Organisations - Other - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Other - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - - The SeaDataNet pan-European infrastructure has been developed by NODCs and major research institutes from 34 countries. Over 100 marine data centres are connected and provide discovery and access to data resources for all - European researchers. Moreover, SeaDataNet is a key infrastructure driving several portals of the European Marine Observation and Data network (EMODnet), initiated by EU DG-MARE for Marine Knowledge, MSFD, and Blue Growth. SeaDataNet complements the - Copernicus Marine Environmental Monitoring Service (CMEMS), coordinated by EU DG-GROW. However, more effective and convenient access is needed to better support European researchers. The standards, tools and services developed must be reviewed and - upgraded to keep pace with demand, such as developments of new sensors, and international and IT standards. Also EMODnet and Copernicus pose extra challenges to boost performance and foster INSPIRE compliance. More data from more data providers must - be made available, from European and international research projects and observing programmes. - - - 2020-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.2."> - - - INFRAIA-01-2016-2017 - Integrating Activities for Advanced Communities - - - RIA - Research and Innovation action - - - France - - - SeaDataCloud - - - H2020-INFRAIA-2016-1 - - - 730960 - - - - - UNIVERSITY OF ULSTER - UNIVERSIDAD DE JAEN - NATIONAL UNIVERSITY OF IRELAND GALWAY - LULEA TEKNISKA UNIVERSITET - HOGSKOLAN I HALMSTAD - UNIVERSITA DEGLI STUDI DI FIRENZE - I+ SRL - KARDE AS - FUNDACION AGEING SOCIAL LAB - ACADEMISCH ZIEKENHUIS GRONINGEN - ASSOCIAZIONE NOVILUNIO - SWEDISH ADRENALINE AB - - - EUR 976 500 - - - The use of computational techniques to Improve compliance to reminders within smartenvironments - - - EUR 1 084 500 - - - United Kingdom - Spain - Ireland - Sweden - Sweden - Italy - Italy - Norway - Spain - Netherlands - Italy - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Higher or Secondary Education Establishments - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The aim of this Project is to create an International and Intersectoral network to facilitate the exchange of staff to progress developments in reminding technologies for persons with dementia which can be deployed in smart - environments. The focus will be on developing staff and partner skills in the areas of user centered design and behavioral science coupled with improved computational techniques which in turn will offer more appropriate and efficacious reminding - solutions. This will be further supported through research involving user centric studies into the use of reminding technologies and the theory of behaviour change to improve compliance of usage. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - United Kingdom - - - REMIND - - - H2020-MSCA-RISE-2016 - - - 734355 - - - - - UNIVERSITAET ZU KOELN - UNIVERSITAET ZU KOELN - - - EUR 1 495 875 - - - An Exascale aware and Un-crashable Space-Time-Adaptive Discontinuous Spectral Element Solver for Non-Linear Conservation Laws - - - EUR 1 495 875 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - "The dynamics of fluids and plasma is described by non-linear conservation laws. Transient behaviour on multiple scales involving turbulence and shocks is intrinsic to these problems. Due to their low dispersion and - dissipation errors, adaptive high order numerical methods currently receive growing attention in academia and industry and form an emerging key technology. The potential benefits are massively improved computational efficiency and drastic reduction - in memory consumption. Both benefits can be easily justified theoretically, in particular for a space-time adaptive high order method. However, due to high algorithmic complexity, the theoretical performance is difficult to sustain on massively - parallel supercomputers. The first challenge that we will address in this project is to design novel, exascale aware, space-time adaptive algorithms and implement them in an open source solver that will scale on over 10^6 computing cores. Another - indispensable property for the successful industrialisation of space-time adaptive high order methods is robustness. Robustness, i.e. an ""un-crashable"" solver, which still retains all the positive benefits of the high order scheme is the ""holy - grail"" of the current research on these methods. This requires new mathematical concepts. The second challenge we will address here is to construct a provable un-crashable, space-time adaptive, high order solver without excessive artificial - dissipation. Our mathematical key to achieve robustness is not intuitive at first sight: skew-symmetry. We will show that a specific skew-symmetric formulation guided by careful mathematics will allow us to design methods that are consistent with the - second law of thermodynamics. This physical consistency is important as it will enable us to construct a new class of un-crashable space-time adaptive high order methods. We will demonstrate the supremacy of this efficient and robust solver in - complex large scale science and engineering applications." - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - Extreme - - - ERC-2016-STG - - - 714487 - - - - - NATIONAL UNIVERSITY OF IRELAND GALWAY - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - ENIOS APPLICATIONS IDIOTIKI KEFALAIOUCHIKI ETAIREIA - METASYSX GMBH - - - EUR 832 500 - - - Targeting IRE1 in disease - - - EUR 886 500 - - - Ireland - France - Greece - Germany - - - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The overarching objective of this Interfere to Suppress or Promote IRE1 (INSPIRED) RISE programme is to drive research and innovation in cell stress and drug development for cancer and neurodegenerative diseases by forming an - interdisciplinary and intersectoral network of experts with strong, dynamic and productive interactions. The partners will work together, each bringing their unique expertise, to develop new classes of therapeutics for these common diseases. By - fostering a shared culture of research, innovation and collaboration, the participants will accelerate advances in the field of cell stress responses. The staff members who participate in the programme will develop new skills, learn new technologies - and be exposed to new environments which will considerably enhance their career opportunities. Advancing drug development in the stress response field has potential translational and commercial opportunities for the participants and will benefit - European society as a whole from economic and health perspectives. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Ireland - - - INSPIRED - - - H2020-MSCA-RISE-2016 - - - 734749 - - - - - UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN - UNIVERSIDAD DE VALLADOLID - LINKOPINGS UNIVERSITET - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - LABORATORIO IBERICO INTERNACIONAL DE NANOTECNOLOGIA - NATIONAL UNIVERSITY OF IRELAND GALWAY - THE QUEEN'S UNIVERSITY OF BELFAST - UNIVERSIDAD COMPLUTENSE DE MADRID - KARLSRUHER INSTITUT FUER TECHNOLOGIE - ZECLINICS SL - LENTIMED MEDICAL DEVICES SL - Experimental Pharmacology and Oncology Berlin-Buch GmbH - XENOPAT SL - ECM INGENIERIA AMBIENTAL SL - ICON CLINICAL RESEARCH LIMITED - OCUPHARM DIAGNOSTICS SL - VORNIA LIMITED - - - EUR 945 000 - - - Drug Discovery and Delivery NEtwork for ONcology and Eye Therapeutics - - - EUR 945 000 - - - Ireland - Spain - Sweden - Ireland - Portugal - Ireland - United Kingdom - Spain - Germany - Spain - Spain - Germany - Spain - Spain - Ireland - Spain - Ireland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Severe ocular disorders are affecting the lives of more than 100Mill people world-wide and at least 25% of the population above 70 years of age, a growing demographic group in EU. More than 8 million people lose their lives to - cancer every year, making cancer a leading cause of pre-mature mortality in the world. The main hallmarks of severe eye conditions (i.e angiogenesis, inflammation and vascular permeability) play also pivotal roles in cancer, being therapeutic targets - to treat both kind of diseases. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Ireland - - - 3D NEONET - - - H2020-MSCA-RISE-2016 - - - 734907 - - - - - MALMO HOGSKOLA - UNIVERSITY OF STRATHCLYDE - UMEA UNIVERSITET - BUNDESANSTALT FUER MATERIALFORSCHUNG UND -PRUEFUNG - SYDDANSK UNIVERSITET - UNIVERSITETET I OSLO - KOBENHAVNS UNIVERSITET - LINNEUNIVERSITETET - - - EUR 2 982 879 - - - Smart capture phases for proteomics, glycomics and biomarker assays - - - EUR 2 982 879 - - - Sweden - United Kingdom - Sweden - Germany - Denmark - Norway - Denmark - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The overall objective of BioCapture is to develop novel robust assays for proteinaceous biomarkers associated with cancer and to develop innovative tools for assaying elusive cancer related posttranslational modifications in - proteins. This will be achieved by exploiting robust glycan, peptide and protein binders in the form of Molecularly Imprinted Polymers (MIPs) or plastic antibodies alongside generic enrichment combined with selected reaction monitoring-based mass - spectrometry assays. In addition, sequence specific MIPs for multiple proteotypic peptides will be developed for use as capture phases in array format followed by MS or fluorescence based readout as well as a coupling of both detection techniques. - The artificial receptors will be developed by various Molecular Imprinting techniques. The research results will lead to technological advances having a major impact on 1) health care since it will profit from methods for earlier, more reliable - diagnosis of diseases, 2) drug discovery allowing a faster target or biomarker identification; and 3) biochemistry research laboratories in resulting in improved protein fractionation tools for revealing low abundant post translational modifications. - The training of researchers will be performed by a consortium consisting of in total 15 partners whereof 6 polymer/materials research groups, 5 protein/glycan chemistry/analysis groups, 1 separation technology companies, 2 expert groups on platforms - for multiplex analysis and one diagnostic company. This forms the basis for a very exciting interdisciplinary training program. Thus 11 early stage researchers (ESRs) working on specific tasks within five work packages will follow a rich training - program providing a well-balanced spectrum of scientific, business and entrepreneurial skills. - - 2020-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Sweden - - - BioCapture - - - H2020-MSCA-ITN-2016 - - - 722171 - - - - - DANMARKS TEKNISKE UNIVERSITET - UNIVERSIDAD AUTONOMA DE MADRID - LUNDS UNIVERSITET - UNIVERSITETET I OSLO - POLITECNICO DI MILANO - UNIVERSITAT DE BARCELONA - FELIXROBOTICS BV - NOVAHEP AB - BIOMODICS APS - - - EUR 4 028 783,40 - - - European Training Network for Cell-based Regenerative Medicine - - - EUR 4 028 783,40 - - - Denmark - Spain - Sweden - Norway - Italy - Spain - Netherlands - Sweden - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The main objective of Training4CRM is to train a new generation of 15 highly inter-disciplinary early stage researchers at the highest international level and quality, who will be immediately employable in both the academic - and industrial sectors due to their highly sought after cross- and interdisciplinary insights and expertise. Training4CRM addresses existing gaps within Cell-based Regenerative Medicine for treatment of neurodegenerative disorders (e.g. Parkinson´s, - Huntington´s, Epilepsy), which occur as a result of progressive loss of structure, function and/or death of neurons in the brain. The disorders have a high prevalence and are associated with impairments and disabilities with high emotional, financial - and social burden. New scientific discoveries and technologies are needed, and Training4CRM sets out with the ambition to educate and train students within and across different scientific disciplines to be able to master the design, fabrication and - testing of completely new tools and materials within the fields of: Micro- and Nanoengineering (nano/microstructures, 3D scaffolds and 3D lab-on-a-chip devices of different materials, geometries, architectures and properties, wireless electronic - components; Biotechnology (human stem cells, human induced pluripotent stem cells, optogenetics, tissue engineering; Pre-clinical studies for the purpose of investigating in vivo, in experimental animals, how the developed cells, materials, - structures affect the animal at the physiological and behavioral levels, unravelling the therapeutic effects of the developed strategies. - - 2020-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Denmark - - - Training4CRM - - - H2020-MSCA-ITN-2016 - - - 722779 - - - - - THE UNIVERSITY OF BIRMINGHAM - FEMTONICS KUTATO ES FEJLESZTO KORLATOLT FELELOSSEGU TARSASAG - MAGYAR TUDOMANYOS AKADEMIA WIGNER FIZIKAI KUTATOKOZPONT - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - ACQUIFER AG - UNIVERSITEIT UTRECHT - ASTON UNIVERSITY - CENTRE EUROPEEN DE RECHERCHE EN BIOLOGIE ET MEDECINE - ART PHOTONICS - M-SQUARED LASERS LIMITED - GLUCOSET AS - FUDAN UNIVERSITY - EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY - - - EUR 1 269 000 - - - Transcribing the processes of life: Visual Genetics - - - EUR 1 269 000 - - - United Kingdom - Hungary - Hungary - Germany - Germany - Netherlands - United Kingdom - France - Germany - United Kingdom - Norway - China - China - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The Visual Genetics (VISGEN) consortium brings together eight academic and five commercial scientifically leading teams to address the unique challenge of visualizing nuclear processes in intact brain in real-time. By - exchanging knowledge between academic and commercial sectors in Europe, as well as undertaking training secondments at leading Universities in China the team will grow its European and global competitiveness in a world-leading forefront of - neuroscience and genetic technology. Visualisation of transcription in living systems has not been witnessed directly, this multidisciplinary and international project will herald a new era where this idea becomes a regular research tool and - translates to a clinical and diagnostic technology in the future. The team will use a unique biotagging platform to develop the technology that is required to interrogate transcription. The intersectoral effort requires the amalgamation of knowledge - from neuroscientists, synthetic chemists, engineers, physicists, analytical chemists, nanobiologists, behavioural scientists, laser technology and image processing experts. The consortium combines expertise from thirteen organisations from seven - countries to build the multidisciplinary team and share the knowledge that addresses and will overcome the task of realising real-time and spatially resolved genetic studies. Once developed, the technology can be utilized for other medical-based - research and development projects aimed at early stage disease diagnosis, cancer detection, and toxicity studies. Real-time visual genetics will transform our understanding of the state-of-the-art and herald transformative changes in the field of - neuroscience, and in general life science. - - 2021-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - United Kingdom - - - VISGEN - - - H2020-MSCA-RISE-2016 - - - 734862 - - - - - "NATIONAL CENTER FOR SCIENTIFIC RESEARCH ""DEMOKRITOS""" - NATIONAL OBSERVATORY OF ATHENS - HELLENIC CENTRE FOR MARINE RESEARCH - ETHNIKO IDRYMA EREVNON - ATHINA-EREVNITIKO KENTRO KAINOTOMIAS STIS TECHNOLOGIES TIS PLIROFOFORIAS, TON EPIKOLNONION KAI TIS GNOSIS - IDRIMA MEIZONOS ELLINISMOU - EPISTIMI EPIKOINONIA - - - EUR 160 000 - - - REsearchers' Nights organized by Athens area Research Institutions to convey the science benefits to the public and motivate young people to science careers - - - EUR 160 000 - - - Greece - Greece - Greece - Greece - Greece - Greece - Greece - - - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Other - - A diverse team of experts in scientific research and science communication from leading Research Institutes and Educational Organizations, located in the Athens Metropolitan area, is formed to organize the Researcher's Night - activities for the years 2016 and 2017. By adopting the concept “Science invites People”, we propose a large scale REN, in 2016, at NCSR "Demokritos", the largest Science Research campus in Greece, and a similar event in 2017 at at the Foundation of - the Hellenic World, a multiplex where science meets entertainment and exploration, organized by the National Observatory of Athens. - - 2017-11-30, closed project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.5."> - - - MSCA-NIGHT-2016 - European Researchers' Night - - - CSA - Coordination and support action - - - Greece - - - RENA - - - H2020-MSCA-NIGHT-2016 - - - 722973 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - ETHNIKO IDRYMA EREVNON - STICHTING OAPEN*OPEN ACCESS PUBLISHING IN EUROPEAN NETWORKS - STIFTUNG DEUTSCHE GEISTESWISSENSCHAFTLICHE INSTITUTE IM AUSLAND - DGIA - GEORG-AUGUST-UNIVERSITAT GOTTINGENSTIFTUNG OFFENTLICHEN RECHTS - UBIQUITY PRESS LIMITED - OPEN BOOK PUBLISHERS COMMUNITY INTEREST COMPANY - DIGITAL RESEARCH INFRASTRUCTURE FOR THE ARTS AND HUMANITIES - UNIVERSITA DEGLI STUDI DI TORINO - - - EUR 1 997 878,13 - - - High Integration of Research Monographs in the European Open Science infrastructure - - - EUR 1 997 878,13 - - - France - Greece - Netherlands - Germany - Germany - United Kingdom - United Kingdom - France - Italy - - - Research Organisations - Research Organisations - Other - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - - HIRMEOS will improve five important publishing platforms for the open access monographs in the SSH and enhance their technical capacities and services, rendering technologies and content interoperable and embedding them fully - into the European Open Science Cloud. The project focuses on the monograph as a significant mode of scholarly communication in the SSH and tackles the main obstacles of the full integration of important platforms supporting open access monographs and - their contents. HIRMEOS will prototype innovative services for monographs in view of full integration in the European Open Science Cloud by providing additional data, links and interactions to the documents, paving the way to new potential tools for - research assessment, which is still a major challenge in the SSH. The platforms participating (OpenEdition Books, OAPEN Library, EKT Open Book Press, Ubiquity Press and Göttingen University Press ) will be enriched with tools that enable - identification, authentication and interoperability (DOI, ORCID, Fundref), and tools that enrich information and entity extraction (INRIA (N)ERD), the ability to annotate monographs (Hypothes.is), and gather usage and alternative metric data. HIRMEOS - will also enrich the technical capacities of the Directory of Open Access Books (DOAB), a most significant indexing service for open access monographs globally, to receive automated information for ingestion, while it will also develop a structured - certification system to document monograph peer-review. Partners will develop shared minimum standards for their monograph publications, such that allow the full embedding of technologies and content in the European Science Cloud. Finally, the - project will have a catalyst effect in including more disciplines into the Open Science paradigm, widening its boundaries towards the SSH. - - 2019-06-30, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.3."> - - - EINFRA-22-2016 - User-driven e-infrastructure innovation - - - RIA - Research and Innovation action - - - France - - - HIRMEOS - - - H2020-EINFRA-2016-1 - - - 731102 - - - - - THE UNIVERSITY OF MANCHESTER - - - EUR 195 454,80 - - - Stable Crosslinked Graphene Membranes for Water and Molecular Separation - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - With less than 1 percent of drinkable water on Earth and growing pollution the demand for drinking water can only be met through the advanced separation and purification technology. Membrane-based filtration technologies are - standard separation processes and are widely used in water treatment; however their performance is still severely limited due to their underperformance in terms of flux, selectivity, porosity, cleaning ability, and stability. Recent advancement in - nanostructured membranes based on layered graphene construct enables a paradigm shift in the membrane development due to its almost zero resistance for water molecules and 100% rejection of other components. Recent reports suggest that an ideal - membrane could be realized using graphene because of its atomic thickness, high mechanical strength, and chemical inertness. Although the graphene based membranes showed excellent separation performance; unfortunately their durability and stability - is the biggest obstacle in realization of its full potential. - - - 2019-08-08, Grant Agreement terminated - - - 2017-08-09 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - StaGraM - - - H2020-MSCA-IF-2015 - - - 707220 - - - - - FORSCHUNGSZENTRUM JULICH GMBH - Gauss Centre for Supercomputing (GCS) e.V. - GRAND EQUIPEMENT NATIONAL DE CALCUL INTENSIF - THE UNIVERSITY OF EDINBURGH - BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION - CSC-TIETEEN TIETOTEKNIIKAN KESKUS OY - Eidgenössische Technische Hochschule Zürich - SURFSARA BV - UPPSALA UNIVERSITET - CINECA CONSORZIO INTERUNIVERSITARIO - INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK - UNINETT SIGMA2 AS - ETHNIKO DIKTYO EREVNAS TECHNOLOGIAS AE - UNIVERSIDADE DE COIMBRA - NATIONAL UNIVERSITY OF IRELAND GALWAY - ISTANBUL TEKNIK UNIVERSITESI - THE CYPRUS INSTITUTE - "ASSOCIATION ""NATIONAL CENTRE FOR SUPERCOMPUTING APPLICATIONS" - VYSOKA SKOLA BANSKA - TECHNICKA UNIVERZITA OSTRAVA - NEMZETI INFORMACIOS INFRASTRUKTURA FEJLESZTESI IRODA - KORMANYZATI INFORMATIKAI FEJLESZTESI UGYNOKSEG - KOBENHAVNS UNIVERSITET - MACHBA - INTERUNIVERSITY COMPUTATION CENTER - PARTNERSHIP FOR ADVANCED COMPUTINGIN EUROPE AISBL - UNIVERZA V LJUBLJANI - VYPOCTOVE STREDISKO SLOVENSKEJ AKADEMIE VIED - CENTRE DE RECHERCHE EN AERONAUTIQUE ASBL - CENAERO - - - EUR 15 000 000 - - - PRACE 5th Implementation Phase Project - - - EUR 16 105 293,69 - - - Germany - Germany - France - United Kingdom - Spain - Finland - Switzerland - Netherlands - Sweden - Italy - Poland - Norway - Greece - Portugal - Ireland - Turkey - Cyprus - Bulgaria - Czech Republic - Hungary - Hungary - Denmark - Israel - Belgium - Slovenia - Slovakia - Belgium - - - Research Organisations - Research Organisations - Other - Higher or Secondary Education Establishments - Research Organisations - Other - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Other - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - - PRACE, the Partnership for Advanced Computing is the permanent pan-European High Performance Computing service providing world-class systems for world-class science. Systems at the highest performance level (Tier-0) are - deployed by Germany, France, Italy and Spain providing researchers with over 11 billion core hours of compute time. HPC experts from 25 member states enabled users from academia and industry to ascertain leadership and remain competitive in the - Global Race. Currently PRACE is in transition to PRACE 2, the successor of the initial five year period. The objectives of PRACE-5IP are to build on and seamlessly continue the successes of PRACE and start new innovative and collaborative activities - proposed by the consortium. These include: assisting the transition to PRACE 2 including an analysis of Trans National Access; strengthening the internationally recognised PRACE brand; continuing and extend advanced training which so far provided - more than 18 800 persontraining days; preparing strategies and best practices towards Exascale computing; coordinating and enhancing the operation of the multi-tier HPC systems and services; and supporting users to exploit massively parallel systems - and novel architectures. A high level Service Catalogue is provided. The proven project structure will be used to achieve each of the objectives in 6 dedicated work packages. The activities are designed to increase Europe's research and innovation - potential especially through: seamless and efficient Tier-0 services and a pan-European HPC ecosystem including national capabilities; promoting take-up by industry and new communities and special offers to SMEs; implementing a new flexible business - model for PRACE 2; proposing strategies for deployment of leadership systems; collaborating with the ETP4HPC, CoEs and other European and international organisations on future architectures, training, application support and policies. This will be - monitored through a set of KPIs. - - 2019-04-30, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.3."> - - - EINFRA-11-2016 - Support to the next implementation phase of Pan-European High Performance Computing infrastructure and services (PRACE) - - - RIA - Research and Innovation action - - - Germany - - - PRACE-5IP - - - H2020-EINFRA-2016-1 - - - 730913 - - - - - KAROLINSKA INSTITUTET - - - EUR 173 857,20 - - - Self and others in the sensorimotor system: a computational neuroanatomy of sensory attenuation - - - EUR 173 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - Why can’t you tickle yourself? Previous behavioural and neuroimaging evidence suggests that when we move one hand to touch the other, the resulting tactile sensation is perceived as less intense compared to identical touches - of external origin. This sensory attenuation (SA) phenomenon is hypothesized to arise because our brains use internal information about the motor command (efference copy) to predict the tactile consequences of the movement and attenuate the tactile - feedback based on these predictions. However, little is known about how the brain produces SA. ‘TICKLE ME’ combines, for the first time, computational motor control theory, force perception behavioural experiments, and state-of-the-art neuroimaging - methods to address how the human brain distinguishes between self-generated and externally-generated touch. - - 2018-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - TICKLE ME - - - H2020-MSCA-IF-2015 - - - 704438 - - - - - SCHWEIZERISCHER NATIONALFONDS ZUR FORDERUNG DER WISSENSCHAFTLICHEN FORSCHUNG - DEUTSCHES ZENTRUM FUER LUFT - UND RAUMFAHRT EV - SOCIEDAD PARA EL FOMENTO DE LA INNOVACION TECNOLOGICA S.L. - INNOVATEC - HERMANN VON HELMHOLTZ-GEMEINSCHAFT DEUTSCHER FORSCHUNGSZENTREN EV - NEDERLANDSE ORGANISATIE VOOR WETENSCHAPPELIJK ONDERZOEK - COMISSAO DE COORDENACAO E DESENVOLVIMENTO REGIONAL DO CENTRO - USTAV FYZIKALNI CHEMIE J. HEYROVSKEHO AV CR, v. v. i. - SERVICE PUBLIC FEDERAL DE PROGRAMMATION POLITIQUE SCIENTIFIQUE - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CONSIGLIO NAZIONALE DELLE RICERCHE - SCIENCE FOUNDATION IRELAND SFI - UNIVERSITE DE LAUSANNE - WROCLAWSKIE CENTRUM BADAN EIT+ SPZOO - - - EUR 1 992 983,75 - - - Towards better Synchronisation of Priority Settings and Evaluation Mechanisms for Research Infrastructures Beyond National Relevance - - - EUR 2 001 983,75 - - - Switzerland - Germany - Spain - Germany - Netherlands - Portugal - Czech Republic - Belgium - France - Italy - Ireland - Switzerland - Poland - - - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - - The main objective of the proposal is to contribute to a better harmonisation and synchronisation of priority-setting-, funding- evaluation and life-cycle management of Research Infrastructures (RI through the exchange of best - practices among the main stakeholders in member states, associated countries and at European level. The regional dimension will explicitly be taken into account by integrating, where appropriate, smart specialisation strategies in the work carried - out. - - 2018-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.3.1., H2020-EU.1.4.3.2."> - - - INFRASUPP-01-2016 - Policy and international cooperation measures for research infrastructures - - - CSA - Coordination and support action - - - Switzerland - - - InRoad - - - H2020-INFRASUPP-2016-1 - - - 730928 - - - - - AARHUS UNIVERSITET - UNIVERSITEIT LEIDEN - HERIOT-WATT UNIVERSITY - UNIVERSITE PAUL SABATIER TOULOUSE III - THE UNIVERSITY OF LIVERPOOL - WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER - UNIVERSITAET ZU KOELN - STICHTING KATHOLIEKE UNIVERSITEIT - GRAPHIC SCIENCE LIMITED - - - EUR 4 009 451,64 - - - The Extensive and Ubiquitous Role of Polycyclic Aromatic Hydrocarbons (PAHs) in Space - - - EUR 4 009 451,64 - - - Denmark - Netherlands - United Kingdom - France - United Kingdom - Germany - Germany - Netherlands - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Large Polycyclic Aromatic Hydrocarbon (PAH) molecules are deeply interwoven in the fabric of the Universe and lock up ~15% of the elemental carbon in the interstellar medium (ISM) of galaxies. They dominate the mid-infrared - emission characteristics of galaxies that can be used to trace star formation locally as well as in the early universe, they influence the phase structure of the ISM and the star formation rate of galaxies, and they are the epitome of molecular - complexity in space, heralding the importance of top-down chemistry. In spite of the influential role of PAHs in the ISM, their lifecycle, catalytic activity, interaction with interstellar radiation, gas and grains and their role in the organic - inventory of solar system bodies is still poorly understood. The EUROPAH ETN aims to change this by creating a highly multidisciplinary network that combines astronomy, molecular physics, molecular spectroscopy, environmental science, quantum - chemistry, surface sciences, and plasma physics in a comprehensive research and training program. EUROPAH will train 16 ESRs through cutting edge individual research and innovation projects investigating key physical and chemical processes of PAHs in - space and related terrestrial settings and linking directly to R&D needs of our industrial beneficiaries. EUROPAH will engage all ESRs in industry driven innovation activities aimed at R&D of the industrial participants products and services, - including outreach activities led by our industrial science communication beneficiary. Research and innovation training is complemented by an extensive program of network-wide training events to expose ESRs to all disciplines in the network and to - instill in them a comprehensive set of transferable skills. This will provide the ESRs with a unique learning environment in a multidisciplinary setting aimed at developing a research oriented creative and innovative mind set and will place them well - for a future career in academia or in industry. - - 2020-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Denmark - - - EUROPAH - - - H2020-MSCA-ITN-2016 - - - 722346 - - - - - UNIVERSITAET ZU KOELN - STOCKHOLMS UNIVERSITET - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - GOETEBORGS UNIVERSITET - MEDICAL RESEARCH COUNCIL - UNIVERSITE DE GENEVE - STICHTING KATHOLIEKE UNIVERSITEIT - UNIVERSITY OF NEWCASTLE UPON TYNE - KHONDRION BV - - - EUR 3 920 630,04 - - - Regulation of mitochondrial expression - - - EUR 3 920 630,04 - - - Germany - Sweden - Germany - Sweden - United Kingdom - Switzerland - Netherlands - United Kingdom - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Mitochondria are essential organelles found in every eukaryotic cell, required to convert food into usable energy. The mitochondrial oxidative phosphorylation (OXPHOS) system, which produces the majority of cellular energy in - the form of ATP, is controlled by two distinct genomes: the nuclear and the mitochondrial genome (mtDNA). Mutations in mitochondrial genes encoded by either genome could cause diseases affecting OXPHOS system, called mitochondrial diseases, whose - prevalence has been estimated to be ≈1:8500. Moreover, dysfunction of mitochondrial OXPHOS system has emerged as a key factor in a myriad of “common” diseases, including neurodegenerative and metabolic disorders like Parkinson’s and Alzheimer’s - Disease, Type 2 Diabetes, and was linked to aging process. Despite all this, it is surprising that our understanding of the mechanisms governing the mitochondrial gene expression and its associated pathologies remain superficial and therapeutic - interventions unexplored. The basic machineries for mtDNA replication, mtDNA transcription and mitochondrial translation are known, but the regulation of these processes in response to metabolic demands is poorly understood. The complex nature of - mitochondrial gene expression that relies on two different genomes calls for a multidisciplinary approach where different teams of researchers join forces. Studies in this area are not only of basic scientific interest but may also provide new - avenues towards treatment of mitochondrial dysfunction in a variety of human diseases. - - 2020-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - REMIX - - - H2020-MSCA-ITN-2016 - - - 721757 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSITY OF LEEDS - Asociacion - Centro de Investigacion Cooperativa en Nanociencias - CIC NANOGUNE - RAITH GMBH - CHALMERS TEKNISKA HOEGSKOLA AB - UNIVERSITAT KONSTANZ - Eidgenössische Technische Hochschule Zürich - GRAPHENEA SA - AALTO-KORKEAKOULUSAATIO - - - EUR 3 884 019,12 - - - QUantum Electronics Science and TECHnology training - - - EUR 3 884 019,12 - - - France - United Kingdom - Spain - Germany - Sweden - Germany - Switzerland - Spain - Finland - - - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - Quantum Electronics provides a challenging and innovative multidisciplinary framework for training young researchers with excellent prospects for a career either in the industry or in academia. In this promising area, the - “Quantum Electronics Science and Technology training” project, with acronym QuESTech, will create a European network of experts providing state-of-the-art training for young researchers in the general field of experimental, applied and theoretical - Quantum Electronics. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - France - - - QuESTech - - - H2020-MSCA-ITN-2017 - - - 766025 - - - - - HASKOLI ISLANDS - UNIVERSITAET BREMEN - THE OPEN UNIVERSITY - TECHNISCHE UNIVERSITAET WIEN - FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG - UNIVERSITETET I OSLO - UNIVERSITAET BIELEFELD - TECHNISCHE UNIVERSITEIT DELFT - EIDGENOSSISCHE MATERIALPRUFUNGS- UND FORSCHUNGSANSTALT - STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN - INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM - TESCAN BRNO SRO - CARL ZEISS SMT GMBH - - - EUR 3 878 757 - - - Low energy ELEctron driven chemistry for the advantage of emerging NAno-fabrication methods - - - EUR 3 878 757 - - - Iceland - Germany - United Kingdom - Austria - Germany - Norway - Germany - Netherlands - Switzerland - Netherlands - Belgium - Czech Republic - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Chemistry is fundamental to nanotechnology, as chemistry can prepare specifically tailored molecules to serve, in a bottom-up approach, as the building blocks for the fabrication of functional and structured nano-materials. - Nanotechnology is the technology of the 21st century with applications from electronics to biotechnology and medicine. The next decade will thus be characterized by an increasing industrial demand for novel nanostructures with individual physical and - chemical properties tuned to specific applications. This, in turn, requires increased flexibility and control over material composition, shape and resolution. To meet this demand the chemistry and the physics behind new and emerging nanoscale - fabrication methods must be well understood and this understanding must be systematically deployed to advance these methods into commercially viable fabrication technologies. Simultaneously to ensure that Europe is a significant player in this - economically and technologically important industry, the European nanotechnology industry must have access to well trained individuals with both the technical skills and a broad understanding of the physical and chemical parameters governing the - performance of next generation processing techniques and, the skills and drive needed for further innovation and entrepreneurship in the nano-technology field. ELENA addresses these scientific and training needs by: i) studying the chemistry - underpinning two emerging nano-technology writing techniques; Focused Electron Beam Induced Processing and Extreme Ultra Violet Lithography, ii) exploiting knowledge gained in (i) to develop these techniques such that they may be made commercially - competitive, and iii) training a new generation of European scientists with a fundamental understanding of the physics and chemistry behind these processes and the mind set for innovation and entrepreneurship to provide an exemplar for up-skilling - European nanotechnology industry. - - 2020-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Iceland - - - ELENA - - - H2020-MSCA-ITN-2016 - - - 722149 - - - - - LUNDS UNIVERSITET - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSITAETSMEDIZIN GOETTINGEN - GEORG-AUGUST-UNIVERSITAET GOETTINGEN - STIFTUNG OEFFENTLICHEN RECHTS - DEUTSCHES ZENTRUM FUR NEURODEGENERATIVE ERKRANKUNGEN EV - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - EXPLORA NOVA SARL - UMECRINE AB - - - EUR 3 129 428,16 - - - Synaptic dysfunction in Neurodegenerative Diseases - - - EUR 3 129 428,16 - - - Sweden - United Kingdom - France - Germany - Germany - Switzerland - France - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Neurodegenerative diseases (NDDs) of aging are a growing burden on societies. Although studies on the degeneration of neurons have been a main focus of research, increasing evidence points to synapses as the site where - Alzheimer’s disease (AD), Parkinson’s disease (PD) and Huntington’s disease (HD) begin. There is growing evidence that synapses are sites of early and aberrant protein misfolding, aggregation and spread in NDDs. A key problem in research on NDDs has - been that the normal physiological roles at synapses of the aggregation-prone proteins (β- amyloid/amyloid precursor protein, tau, α-synuclein and huntingtin), which are linked pathologically and genetically to these diseases, are not known. Using - cutting-edge technologies and multidisciplinary approaches the SYNDEGEN consortium aims to bring together leading experts in cell biology, synapse biology and imaging, stem cell biology and NDDs in Europe to determine the molecular and cellular - mechanisms whereby synapses become dysfunctional in AD, PD and HD for the purpose of developing novel therapies. The goal of the consortium is to train talented young scientists in interdisciplinary, innovative and collaborative research aimed at the - development of novel molecular based treatment strategies for these major diseases of aging. A gap in the training of students in these important diseases is that disease expertise and novel methods to study synapses are localized in isolated groups - in different locations in the EU. Similar questions are being asked about the mechanisms of synaptic dysfunction in AD, PD and HD, but no one university or company has sufficiently broad knowledge and technical expertise required to study and develop - therapies for synaptic dysfunction in these disorders. This training programme will be implemented in 6 academic centres and 2 SMEs representing a comprehensive, highly interactive and multidisciplinary partnership. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Sweden - - - SYNDEGEN - - - H2020-MSCA-ITN-2016 - - - 721802 - - - - - NATIONAL UNIVERSITY OF IRELAND GALWAY - UNIVERSITAET REGENSBURG - RIJKSUNIVERSITEIT GRONINGEN - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - ERNST-MORITZ-ARNDT-UNIVERSITÄT GREIFSWALD - UMEA UNIVERSITET - NATAC BIOTECH SL - UNIVERSITY OF DUNDEE - NIZO FOOD RESEARCH BV - UNIVERSITY OF NEWCASTLE UPON TYNE - NESTEC S.A - - - EUR 3 385 026,36 - - - Training Network to Understand and Exploit Mechanisms of Sensory Perception in Bacteria - - - EUR 3 385 026,36 - - - Ireland - Germany - Netherlands - Spain - United Kingdom - Germany - Sweden - Spain - United Kingdom - Netherlands - United Kingdom - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The PATHSENSE (Pathogen Sensing) ETN will bring together an interdisciplinary team of world-leading researchers from Europe to tackle a highly ambitious scientific project, focusing on the molecular mechanisms of sensory - perception in bacterial pathogens. PATHSENSE will establish an innovative doctoral training programme that will deliver 13 PhD graduates and high-impact scientific outputs. The relationship between molecular structures and biological function is - central to understanding any living system; however the research methodologies required to unravel these relationships are often complex and fast-changing. The team participating in this Network has the infrastructure and track-record to train ESRs - in these state-of-the art methodologies, including structural biology, proteomics & protein biochemistry, molecular biology, bacterial genetics, food microbiology, mathematical modelling, cell biology, microscopy and comparative genomics. - PATHSENSE will investigate the poorly understood structure-function relationships that exist within a large multi-protein complex called a “stressosome”, which acts as a sensory organelle in bacteria. The project will involve extensive inter-sectoral - mobility of the ESRs across 7 EU countries to make full use of the complementary skills available at each of the hosting institutions. The inter-sectoral Network comprises 8 leading Universities, 1 public research institution, 4 companies (from - spin-off to large multi-national) and 1 governmental agency. A major objective of this Network will be to exploit the fundamental research to develop novel antimicrobial treatments that have applications in the food and public health sectors. This - project will deliver high-impact science, 13 highly-trained innovative researchers and will produce a long-lasting inter-sectoral network of collaborators who will continue to work together to exploit fundamental research for the socio-economic - benefit of Europe. - - 2021-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Ireland - - - PATHSENSE - - - H2020-MSCA-ITN-2016 - - - 721456 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - ETHNIKO IDRYMA EREVNON - STICHTING OAPEN*OPEN ACCESS PUBLISHING IN EUROPEAN NETWORKS - STIFTUNG DEUTSCHE GEISTESWISSENSCHAFTLICHE INSTITUTE IM AUSLAND - DGIA - KNOWLEDGE UNLATCHED CIC - - - EUR 408 586,25 - - - Design for Open access Publications in European Research Areas for Social Sciences and Humanities - - - EUR 408 586,25 - - - France - Greece - Netherlands - Germany - United Kingdom - - - Research Organisations - Research Organisations - Other - Research Organisations - Other - - OPERAS-D (Design) project will support the 5 main partners (“core group”) of the OPERAS network in the development of a European e-infrastructure for open access publications in the Social Sciences and Humanities (SSH). The - project will address long-term requirements for the development of the e-infrastructure and community building, as well as seek to expand other interested parties within and beyond Europe, and in diverse fields of the SSH. - - - 2018-06-30, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.3.1., H2020-EU.1.4.1.3., H2020-EU.1.4.3.2."> - - - INFRASUPP-03-2016 - Support to policies and international cooperation for e-infrastructures - - - CSA - Coordination and support action - - - France - - - OPERAS-D - - - H2020-INFRASUPP-2016-1 - - - 731031 - - - - - UNIVERSITEIT VAN AMSTERDAM - UNIVERSITEIT VAN AMSTERDAM - - - EUR 2 493 318 - - - A Unified Framework for the Assessment and Application of Cognitive Models - - - EUR 2 493 318 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Cognitive models formalize substantive theory about how people reason, learn, decide, and act. Cognitive models also serve as measurement tools that explain observed behavior in terms of constituent psychological processes. - Because of their unique ability to estimate latent processes, cognitive models are increasingly applied throughout cognitive neuroscience and clinical psychology. Despite their theoretical appeal and growing popularity, however, the field of - cognitive modeling presents an often bewildering proliferation of ideas and techniques. Current applications appear idiosyncratic, and the state-of-the-art remains unclear. This lack of systematicity makes it difficult for researchers and - practitioners to develop, understand, and apply important cognitive models. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Netherlands - - - UNIFY - - - ERC-2016-ADG - - - 743086 - - - - - SABANCI UNIVERSITESI - - - EUR 251 053,20 - - - A Mechanism Design and Cheap Talk Approach to Mediation - - - EUR 251 053,20 - - - Turkey - - - Higher or Secondary Education Establishments - - Mediation is an alternative dispute resolution (ADR) technique. If two or more parties are in disagreement, then they can take the case to a court and let the judge give the final decision. Alternatively, the disputing parties - can get the help of an experienced, neutral third party (i.e., the mediator) who facilitates a negotiation and help the disagreeing parties reach an agreement short of litigation. The mediation process is private and confidential, possibly enforced - by law (European Mediation Directive 2008). The rising popularity of mediation can be explained by the increasing workload of courts, by the fact that mediation is less costly than litigation, and by the desire of some control over the final - decision. - - 2018-07-31, ongoing project | - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Turkey - - - Mediation - - - H2020-MSCA-IF-2014 - - - 659780 - - - - - CONSIGLIO PER LA RICERCA IN AGRICOLTURA E L'ANALISI DELL'ECONOMIA AGRARIA - UNIVERSITA DEGLI STUDI DI MILANO - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - KWS LOCHOW GMBH - KEYGENE NV - - - EUR 486 000 - - - Exploring the molecular control of seed yield in crops - - - EUR 792 000 - - - Italy - Italy - Spain - Germany - Netherlands - - - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - ExpoSEED aims to integrate forward and reverse genetic approaches to dissect the molecular mechanisms that control seed/kernel (hereafter referred as seed) yield in model species and to transfer the acquired knowledge to - selected crops as legumes and cereals. The identification of “molecular hubs” that determine seed number and size will put the basis for the development of breeding tools to improve seed production at the beginning of the seed market. - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Italy - - - ExpoSEED - - - H2020-MSCA-RISE-2015 - - - 691109 - - - - - LUNDS UNIVERSITET - TECHNISCHE UNIVERSITAET DRESDEN - LINNEUNIVERSITETET - MOLECULAR SENSE LTD - BAR ILAN UNIVERSITY - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - - - EUR 6 084 949 - - - Parallel network-based biocomputation: technological baseline, scale-up and innovation ecosystem - - - EUR 6 084 949 - - - Sweden - Germany - Sweden - United Kingdom - Israel - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - - Many technologically and societally important mathematical problems are intractable for conventional, serial computers. Therefore, a significant need exists for parallel-computing approaches that are capable to solve such - problems within reasonable time frames. Recently, part of our consortium demonstrated proof-of-principle of a parallel-computation system in which a given combinatorial problem is encoded into a graphical, modular network that is embedded in a - nanofabricated planar device. The problem is then solved by a large number of independent biological agents, namely molecular-motor-propelled protein filaments, exploring the network in a highly parallel fashion (PNAS 113, 2591 (2016)). Notably, this - approach uses orders of magnitude less energy than conventional computers, thus addressing issues related to power-consumption and heat-dissipation. Within Bio4Comp we (i) will establish the technological and scientific basis for robust upscaling of - this approach, (ii) will demonstrate scalability by systematically increasing the problem size by several orders of magnitude, and (iii) will develop new algorithms with the aim to open up a wide range of applications. Additionally, we will (iv) help - foster and structure an ecosystem of scientists and companies that will accelerate the path to market acceptance, including the creation of a joint roadmap. Benefits to society will include the ability to solve hitherto intractable problems, and the - development of a sustainable and energy-efficient computing approach that is radically different from current information and communications technology. - - 2021-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.2."> - - - FETPROACT-01-2016 - FET Proactive: emerging themes and communities - - - RIA - Research and Innovation action - - - Sweden - - - Bio4Comp - - - FETPROACT-2016 - - - 732482 - - - - - STICHTING KATHOLIEKE UNIVERSITEIT - STICHTING KATHOLIEKE UNIVERSITEIT - - - EUR 150 000 - - - A biomechanically driven, patient specific pre-planning and surgical tool to optimize placement of a novel meniscus prosthesis - - - EUR 150 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In this BioMechMeniscus project we will develop a workflow for optimal placement of a novel meniscus implant. The medial meniscus implant (named ‘Trammpolin’) has been developed using methods developed during the BioMechTools - project such as 1) principle component analyses based on MRI-segmented image to assess the anatomical shape of the meniscus, 2) assessing sensitivity of cartilage stresses and implant strains on size and design-parameters using finite element - techniques and 3) utilizing load-predictions from our award-winning musculoskeletal models. - - - 2019-04-30, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Netherlands - - - BioMechMeniscus - - - ERC-2017-PoC - - - 768338 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 264 668,40 - - - Understanding the Commitment in Organized Crime - - - EUR 264 668,40 - - - France - - - Research Organisations - - This project is structured around a central question: how do individuals get involved in organized crime? To answer it, the analysis will focus on the social conditions of the criminal commitment and promotion towards superior - spheres of drug trafficking. I will use the notion of “criminal career,” increasing and updating the existing knowledge on the steps that allow an upward social mobility. This problematic implies first to describe and analyze the universe of - organized crime, its subdivisions, its hierarchies, its divides, and the structure of its opportunities. Then, it also necessary to put the framework of the biographical trajectories into a historical, social and political perspective. - - - 2021-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - France - - - UCOC - - - H2020-MSCA-IF-2016 - - - 752743 - - - - - KOBENHAVNS UNIVERSITET - - - EUR 212 194,80 - - - Regulation and Metabolic Engineering of Saponins for use as bio-pesticides. - - - EUR 212 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - Insect pests and pathogens cause major losses in agriculture, and there is a critical need to develop novel and sustainable methods to reduce these losses. Plants produce a vast diversity of specialized chemicals that deter - antagonist, but in spite of their potential for pest management they are still largely unexplored. We need to understand better how such defence compounds are synthesized by plants and what biotic and abiotic conditions trigger and regulate their - production, in order to develop and use them sustainably. The objective of my REMES project is to uncover the genetic and molecular regulation of triterpenoid saponin biosynthesis, using the insect-resistant wild crucifer Barbarea vulgaris as a model - system, and explore their use as bio-pesticides. I will 1) characterize transcriptional regulators of the saponin biosynthetic pathway; 2) explore how saponin biosynthesis responds to different functional types of insects and pathogens in B. - vulgaris; and 3) manipulate the regulatory responses and production of saponins to assess their potential as sustainable bio-pesticides. In the project, I will take advantage of the experience and state-of-the-art facilities at the host in systems - biology, molecular biology, biochemistry, bioinformatics, metabolomics and plant-insect interactions; in turn, I will contribute my own expertise in characterization of transcriptional regulation of specialized metabolism in plants. With the project - I will consolidate my career in research whilst also developing important academic and transferrable skills for pursuing a future career in academia. Altogether, the project will improve our understanding of saponin biosynthesis and regulation, which - will improve the industrial interest and means to develop crops with modified content of saponins and ecologically appropriate defence reactions, either through classical breeding or genetic engineering. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - REMES - - - H2020-MSCA-IF-2016 - - - 752437 - - - - - THE UNIVERSITY OF BIRMINGHAM - - - EUR 195 454,80 - - - Defining the immunological interplay between fibroblastic reticular cells and anti-tumour T cells - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Lymph nodes are sites where immune responses are robustly initiated. Paradoxically, they are also very common metastatic sites, where tumour progression is well-tolerated. Robust evidence defines a role for fibroblastic - reticular cells (FRCs) in preventing T cells from acquiring effector functions within lymph nodes, and deleting T cells that show self-reactivity. FIBROCAN will test the hypothesis that FRCs systematically shut down anti-tumour T cell responses, - testing mechanisms of suppression in vitro and in vivo, and charting tumour antigen presentation by FRCs to T cells for the first time. - - - 2018-06-30, Grant Agreement terminated - - - 2016-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - FIBROCAN - - - H2020-MSCA-IF-2015 - - - 707525 - - - - - KING'S COLLEGE LONDON - - - EUR 183 454,80 - - - Logical and Psychological Foundations for a Teleosemantic Theory of Productivity - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - How can we understand sentences we’ve never heard before? What distinguishes meaningful things from nonmeaningful things? These questions pose the problems of productivity and intentionality, respectively. - - - 2019-08-31, Grant Agreement terminated - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - TeleoLogic - - - H2020-MSCA-IF-2016 - - - 741316 - - - - - KATHOLIEKE UNIVERSITEIT LEUVEN - - - EUR 160 800 - - - Multifunctional Cellulose Magnetic Hybrid (CMH) Nanomaterial for Integrating Downstream Processing of Microalgae - - - EUR 160 800 - - - Belgium - - - Higher or Secondary Education Establishments - - Microalgae are a promising new biomass source for the production of chemicals and biofuel. Notwithstanding extensive R&D efforts, the cost and energy demand the production process remain too high, particularly in - downstream processing. We believe the efficiency of microalgae downstream processing can be greatly improved through the use of nanotechnology. Hybrid and/or multifunctional nanoparticles can be tailored with multiple functional groups to combine - several unit operations in a single technology. In this project, we combine expertise on Fe3O4 nanomaterials and cell disruption technologies from the experienced researcher with expertise of the two co-supervisors in nanocellulose materials and - microalgae harvesting to create a bio-based and re-usable Cellulose Magnetic Hybrid (CMH) nanomaterial for downstream processing of microalgae. As a basis we will use nanocellulose, a natural material that can easily be grafted with multiple - functional groups. The nanocellulose will be equipped with quaternary ammonium groups to generate flocculating and cell disruption activity, as well as pH-responsive to allow detachment of the nanomaterial after processing. The nanocellulose will be - linked to an Fe3O4 nanoparticles, which will allow separating the microalgal biomass from the medium as well as recovery of the nanomaterial after downstream processing. Thus, our CMH nanomaterial will be capable of combined flocculation, dewatering - and cell disruption of microalgae and can be removed from the biomass and re-used after processing. The techno-economic feasibility of this novel technology will be demonstrated in two model systems: lipid production in Nannochloropsis and - astaxanthin production in Haematococcus. We believe that this CMH nanomaterial will be able to achieve a critical cost reduction in microalgal downstream processing and truly advance large-scale microalgae biomass production towards - commercialization. - - 2019-08-01, ongoing project - - - 2017-08-02 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Belgium - - - CMHAlgae - - - H2020-MSCA-IF-2016 - - - 751637 - - - - - UNIVERSITEIT VAN AMSTERDAM - - - EUR 177 598,80 - - - Synthetic magnetism with ultracold Fermi gases of strontium - - - EUR 177 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Since the first observation of a gaseous Bose Einstein condensate , ultracold atoms have provided a unique perspective into the quantum world. In a few seconds a piece of hot metal is transformed into an extremely dilute, - nanokelvin gas, which is governed by quantum statistics - a new state of matter. Quantum gases are so versatile that with the same apparatus one can, for example, explore superfluidity and ultracold chemical reactions, or even search for changes in - fundamental constants . A new frontier of physics, with multidisciplinary appeal, explores topological states of matter, such as the ones predicted to emerge when quantum gases are immersed in a synthetic gauge field. - - 2017-07-31, closed project | - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - SYMULGAS - - - H2020-MSCA-IF-2014 - - - 661171 - - - - - UNIVERSITY COLLEGE LONDON - - - EUR 195 454,80 - - - Situating the New Urban University: Higher Education in an Era of Global Urbanization - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The global impact of urbanization presents unprecedented opportunities and profound challenges for universities. It significantly impacts the expectations placed on universities and where in the world – and the city – they - need to adapt their institutional infrastructures, pedagogical practices and ways of operating. The multiscalar networks of global urbanization mean urban universities must be understood as being more than simply located ‘in the city’. The ‘new urban - university’ is regionalizing and globalizing in dramatic, chaotic ways. What capacities do universities have as urban leaders in a globalizing world? How can universities better mobilize in, and for, extended city-regions? How can marginalized urban - communities inform universities’ spatial and strategic actions? Situating the New Urban University responds to the challenges of global urbanization by illustrating how higher education providers can better serve people in places, versus drawing - people to a place. By taking stock of the influence major sociospatial changes in urban regions have on universities (e.g. globalization, neoliberalization), the project: (1) provides an international assessment of universities’ engagement practices - and impacts; and (2) presents a major comparative examination of higher education systems at the city-regional scale. In-depth studies of universities’ spatial strategies in the London and New York global city-regions will speak directly to best - practices in creating and sustaining reflexive, resilient university-society networks for diverse communities in urban contexts. Stakeholder involvement from the initial phases of the research allows the project to integrate direct input from in the - research design and outputs. Situating the New Urban University deepens academic and policy understandings of how knowledge transfer takes place in global city-regions, enabling higher education and urban policymakers to optimize universities’ - contributions and societal impact. - - 2017-09-30, Grant Agreement terminated - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - NEW URBAN UNIVERSITY - - - H2020-MSCA-IF-2014 - - - 657522 - - - - - UNIVERSITY OF WOLVERHAMPTON - NOTTINGHAMSHIRE HEALTHCARE NHS FOUNDATION TRUST - ALZHEIMER EUROPE - UNIVERSITE DU LUXEMBOURG - UNIVERSITEIT TWENTE - STICHTING ZORGGROEP SINT MAARTEN - PANTON BV - TECHNISCHE UNIVERSITAET DRESDEN - ALEXIANER ST. HEDWIG KLINIKEN BERLIN GMBH - FUNDACIO EURECAT - PIBARQUITECTURASIX SLP - FUNDACION INTRAS - UNIVERSITAT POLITECNICA DE CATALUNYA - DU IT SOCIETA A RESPONSABILITA LIMITATA - QUEENSLAND UNIVERSITY OF TECHNOLOGY - QLD QUT - - - EUR 531 000 - - - Designing for People with Dementia: designing for mindful self-empowerment and social engagement - - - EUR 535 500 - - - United Kingdom - United Kingdom - Luxembourg - Luxembourg - Netherlands - Netherlands - Netherlands - Germany - Germany - Spain - Spain - Spain - Spain - Italy - Australia - - - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - This project aims to help people with dementia engage in social contexts to improve psychosocial wellbeing. People who are affected by Alzheimer’s disease or other dementias often face cognitive, behavioural and psychosocial - difficulties, including impairment and degeneration of memory and of perceptions of identity. In a social context, this can cause difficulties of recognizing, relating to and empathising with other people. These difficulties often pose a challenge - for engaging socially, reinforcing their effects and reducing personal well-being. - - - 2020-02-29, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - United Kingdom - - - MinD - - - H2020-MSCA-RISE-2015 - - - 691001 - - - - - UNIVERSITY OF BRISTOL - - - EUR 183 454,80 - - - Large Deviations and Measure Rigidity in Dynamics - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The proposition aims to develop new tools in ergodic theory and dynamical systems, and explore applications to problems related to mathematical physics, geometry and arithmetics. The first general objective is to advance large - deviation theory for non-compact dynamical systems. We plan to deduce new subexponential large deviation bounds for Gibbs measures on the countable Markov shift and explore how these results are linked to applications such as Pomeau-Manneville - dynamics describing intermittence in the theory of turbulent flows, dynamical properties of the Gauss map, which is deeply connected to Diophantine approximation, and homogeneous dynamics such as the Teichmüller flow on translation surfaces. The - second general objective is to investigate Host-type measure rigidity theory for toral automorphisms and homogeneous dynamics. This topic relates to currently ongoing research on measure classification theorems, which have been influential in several - applications such Diophantine approximation and quantum ergodicity. - - 2017-08-31, closed project | - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - LDMRD - - - H2020-MSCA-IF-2014 - - - 655310 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 195 454,80 - - - A bird’s (social) life: development and senescence in wild social networks. - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Over the course of an individual’s lifetime, the strength and type of social interactions change markedly with age. Because social interaction underpins many aspects of fitness, the contributions of age-related changes in - social behaviour to fitness variation are a key process to understand. Yet, little work has been possible owing to the challenges of quantifying social behaviour in large numbers of individuals over their lifetimes. I thus aim at testing the - hypothesis that age-related variation in social behaviour contributes to age-related changes in survival and reproduction. The project will make the most of the exceptional novel infrastructure and statistical approaches developed by my host group in - Oxford to quantify and manipulate social interactions in free-living birds. - - 2019-08-31, Grant Agreement terminated - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SOCIALIFE - - - H2020-MSCA-IF-2016 - - - 752084 - - - - - AGENZIA NAZIONALE PER LE NUOVE TECNOLOGIE, L'ENERGIA E LO SVILUPPO ECONOMICO SOSTENIBILE - THE QUEEN'S UNIVERSITY OF BELFAST - THE UNIVERSITY OF WARWICK - CALIFORNIA INSTITUTE OF TECHNOLOGYCORP - - - EUR 342 000 - - - BIaxial STRETCHing of PLLA-WS2 nanocomposites FOR thinner and stronger BIOMEDical scaffolds - - - EUR 400 500 - - - Italy - United Kingdom - United Kingdom - United States - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - New materials are now opening clinical treatments in which a temporary scaffold is used to support regeneration of healthy tissue. The specific need that inspires our research is for thinner and stronger bioresorbable vascular - scaffolds (BVS) for coronary heart disease. BVS are poised to replace metal stents due to the excellent clinical outcomes: beyond keeping the vessel open during the first six months after surgery, the BVS leaves behind a healthy blood vessel after - the scaffold is gone, being completely absorbed by the body approximately two years after surgery. The material that has achieved clinical approval for BVS is poly(L-lactic acid), PLLA. It is not as strong and stiff as metals, so the scaffold is - three times thicker than the metal stents, making it more difficult for surgeons to move through arteries to reach the site of the lesion. Thinner Scaffolds that can be seen by x-ray imaging during surgery would facilitate adoption of the technology - and benefit thousands of patients in the EU and US. The proposed Action will provide the fundamental understanding needed to reinforce PLLA by tungsten disulphide (WS2) nanotubes to achieve both the strength and x-ray opacity needed. Improving - materials for BVS requires an interdisciplinary approach by materials science, polymer processing, and bioengineering. The proposed Action will connect EU scientists with a polymer scientist at Caltech in the US who has specialized knowledge of PLLA - BVS and the relevant structure-processing-property relationships (Kornfield). European scientists bring expertise in WS2 nanotubes that are powerful additives for enhancing polymer properties (Di Luccio), compounding polymers with nanotubes - (McNally), biaxial stretching to induce strength and orientation in polymers (Menary), multiscale modeling to connect nanoscale to continuum scale (Figiel), multimethod characterization of structure in nanocomposites (Schiller) and the response of - cells to nanoparticles (Kornfield). - - 2020-01-31, ongoing project - - - 2016-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Italy - - - Bi-Stretch-4-Biomed - - - H2020-MSCA-RISE-2015 - - - 691238 - - - - - FUNDACIO INSTITUT CATALA DE NANOCIENCIA I NANOTECNOLOGIA - CONSIGLIO NAZIONALE DELLE RICERCHE - Teknologian tutkimuskeskus VTT Oy - UNIVERSITAT POLITECNICA DE VALENCIA - UNIVERSITE DES SCIENCES ET TECHNOLOGIES DE LILLE - LILLE I - UNIVERSITA POLITECNICA DELLE MARCHE - MENAPIC SAS - - - EUR 2 915 885,75 - - - All-Phononic circuits Enabled by Opto-mechanics - - - EUR 2 915 886,25 - - - Spain - Italy - Finland - Spain - France - Italy - France - - - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - This project is at the intersection of photonics, RF signal processing and phononics, aiming to achieve an all-optical phononic circuit using coherent phonons as the state variable. The concept is based on cavity optomechanics - (OM) to develop GHz- frequency in-chip phononic circuits for room temperature operation. The circuits will integrate OM-pumped phonon sources and detectors as well as phonon processing components (waveguides, splitters, memories, photonic RF signal - processing) to process information with phonons outside the cavity. The project seeks to prove two concepts. One is the efficient generation of GHz to tens of GHz coherent phonons, coupling them efficiently into a waveguide, engineering their - propagation with low losses and detecting them at room temperature. The other is the synchronisation of two or more self-sustained OM cavities, which relies on the integration of several phononic components. Phonon-based processing will enable - on-chip synchronisation and transfer of information carried between optical channels by phonons, which could eventually serve as a future scalable platform for, e.g., practical information processing with phonons. The technical work is organised in - three work-packages: Theory, Components and Integration. The consortium is made up by three leading research institutes, three universities with an internationally recognised track-record in their respective areas of expertise and an industrial - partner bringing their photonics, phononics, optomechanics, electrical engineering, integration, nanofabrication, theory, multi-physics/multi-scale modelling, instrumentation and application of detectors to the project. - - 2019-08-31, ongoing project | - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-1-2014 - FET-Open research projects - - - RIA - Research and Innovation action - - - Spain - - - PHENOMEN - - - H2020-FETOPEN-2014-2015-RIA - - - 713450 - - - - - LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE - LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE - UNIVERSIDADE FEDERAL DA BAHIA - UNIVERSITY OF BRISTOL - ST GEORGE'S HOSPITAL MEDICAL SCHOOL - MEDICAL RESEARCH COUNCIL - Massey University - - - EUR 2 348 803 - - - Understanding asthma phenotypes: going beyond the atopic/non-atopic paradigm - - - EUR 2 348 803 - - - United Kingdom - United Kingdom - Brazil - United Kingdom - United Kingdom - United Kingdom - New Zealand - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - - Fifteen years ago it was widely believed that asthma was an allergic/atopic disease caused by allergen exposure in infancy; this produced atopic sensitization and continued exposure resulted in eosinophilic airways - inflammation, bronchial hyper-responsiveness and reversible airflow obstruction. It is now clear that this model is at best incomplete. Less than one-half of asthma cases involve allergic (atopic) mechanisms, and most asthma in low-and-middle income - countries is non-atopic. Westernization may be contributing to the global increases in asthma prevalence, but this process appears to involve changes in asthma susceptibility rather than increased exposure to “established” asthma risk factors. - Understanding why these changes are occurring is essential in order to halt the growing global asthma epidemic.This will require a combination of epidemiological, clinical and basic science studies in a variety of environments. - - - 2020-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - AsthmaPhenotypes - - - ERC-2014-ADG - - - 668954 - - - - - UNIVERSITEIT VAN AMSTERDAM - UNIVERSITEIT VAN AMSTERDAM - CENTRAAL BUREAU VOOR DE STATISTIEK - - - EUR 2 499 533 - - - Intergenerational Reproduction and Solidarity in an Era of Family Complexity - - - EUR 2 499 533 - - - Netherlands - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - One of the important consequences of the Second Demographic Transition has been the increasing complexity of families. The aim of this project is to study how rising family complexity has affected two fundamental aspects of - intergenerational relationships: reproduction and solidarity. Theoretically, family complexity is distinguished into four dimensions: (a) the length, timing and nature of exposure to the child, (c) biological relatedness to the child, and (c) - characteristics of parent-parent ties (triadic effects), (d) characteristics of the wider family network. Using insights from several disciplines, I develop a common theoretical framework for understanding intergenerational reproduction and - solidarity. To test the theory, an innovative multiactor survey is developed with an oversampling strategy in which for each adult child, information is collected on all parent figures, and for each parent, information on all adult children. In - addition, register data are used to analyze one aspect of reproduction in a dynamic fashion (educational reproduction) and vignette data are used to analyze one aspect of solidarity in more depth (norms prescribing solidarity). By studying - reproduction and solidarity as outcomes, I shift the traditional focus from examining how the SDT has affected individual well-being, to the question of how the SDT has affected relationships. In doing so, I analyze a new problem in demography and - sociology and contribute to classic debates about population ageing and social inequality. Theoretically, the study of family complexity yields unique opportunities to test ideas about the nature of intergenerational relationships and will shed new - light on the traditional dichotomy of social vis-à-vis biological bases of intergenerational relationships. Methodological innovation is made by developing solutions for well-known problems of multiactor data, thereby strengthening the theoretical - relevance of survey data for the social sciences. - - 2020-10-31, ongoing project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Netherlands - - - FamilyComplexity - - - ERC-2014-ADG - - - 669334 - - - - - THE UNIVERSITY OF WARWICK - EURECOM - UNIVERSITA DEGLI STUDI DI SASSARI - PARIS-LODRON-UNIVERSITAT SALZBURG - SOCIAL CURRENCIES MANAGEMENT S.L. - XLAB RAZVOJ PROGRAMSKE OPREME IN SVETOVANJE DOO - MICHIGAN STATE UNIVERSITY - INSTITUTE OF AUTOMATION CHINESE ACADEMY OF SCIENCES - UNIVERSIDADE ESTADUAL DE CAMPINAS - HONG KONG BAPTIST UNIVERSITY - NANYANG TECHNOLOGICAL UNIVERSITY - SOUTH CHINA UNIVERSITY OF TECHNOLOGY - NEW JERSEY INSTITUTE OF TECHNOLOGY - INDRAPRASTHA INSTITUTE OF INFORMATION TECHNOLOGY DEHLI - THE UNIVERSITY OF SYDNEY - CENTRO DE APLICACIONES TECNOLOGICAS DE AVANZADA - MONASH UNIVERSITY SUNWAY CAMPUS MALAYSIA SDN BHD - - - EUR 2 025 000 - - - Computer Vision Enabled Multimedia Forensics and People Identification - - - EUR 2 025 000 - - - United Kingdom - France - Italy - Austria - Spain - Slovenia - United States - China - Brazil - Hong Kong - Singapore - China - United States - India - Australia - Cuba - Malaysia - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Forensics is a well-established science that aims at applying various disciplines to the law, both civil and criminal, in order to solve questions related to crime. It is mainly concerned with proving and investigating - infringements, identifying perpetrators and describing modus operandi. Biometrics, on the other hand, is a relatively new science that aims at measuring and analysing a person's unique characteristics, both behavioural and physical. It is mainly - concerned with the development of technological solutions to extract and evaluate a person's biometric data mainly for verification and identification purposes. - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - United Kingdom - - - IDENTITY - - - H2020-MSCA-RISE-2015 - - - 690907 - - - - - UNIVERSITEIT VAN AMSTERDAM - - - EUR 177 598,80 - - - Effectiveness evaluation of traditional and third wave Emotion Regulation strategies in clinical and non-clinical youth population - - - EUR 177 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Mental-Health problems in youth such as disruptive behavioural disorders, substances abuse, aggressive behaviors, depression, anxiety, etc. is an expanding and global concern. Numerous Mental-Health problems in youth are - significantly related with poor capacity of Emotion Regulation (ER). Adaptive ER strategies influence the intensity, duration, and expression of emotions, modifying emotional reactions in a socially tolerable and sufficiently flexible way. Thus, - learning adaptive ER strategies has strong potential in promoting physical and psychological well-being in youth. However, the promise of an easy access and implementation of ER programs remains disappointedly unrealised for the following reasons. - (1) Learning of ER competencies is almost invisible in European school curricula. (2) There is a lack of studies in youth that compare ER strategies to provide sufficient evidence-based criteria and guidelines. (3) The needs of the digital natives’ - generation have not been taken into consideration in ER programs, often lacking the engaging and motivational aspects and a high quality assessment. (4) There is an issue of adaptability of ER interventions to the school context. Thus, the main - objective of PEACEFUL MIND is to develop an attractive program, using Information and Communication Technologies, as well as ecological and objective measures, to teach youths adaptive ER strategies. By doing so, we will directly influence social, - emotional, and cognitive development of youths that will have an impact during their entire lives. Finally, the multidisciplinary training objective will provide an extensive clinical training in third wave therapies, training in research - methodology, gaining experience in teaching, tutoring, and additional research competencies, which will open up the opportunity to become an expert in both the academic and private sectors, and will greatly contribute to my objective of becoming a - scientific leader in third wave therapies and e-health. - - 2018-09-28, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - PEACEFUL MIND - - - H2020-MSCA-IF-2014 - - - 656333 - - - - - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - RIJKSUNIVERSITEIT GRONINGEN - - - EUR 1 500 000 - - - Substrate import at work: single-molecule studies of ABC transporters - - - EUR 1 500 000 - - - Germany - Germany - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - ABC (ATP Binding Cassette) transporters represent the most abundant and diverse family of transport proteins known that play crucial roles in numerous cellular processes. Despite their importance, all proposed molecular models - for transport are based on indirect evidence due to the inability of classical biophysical and biochemical techniques to directly visualize dynamic structural changes. To solve this problem, I suggest a novel approach that can decipher the molecular - mechanisms of transport, with the ultimate goal to use this knowledge against pathogenic bacteria, for treatment of ABC-related diseases or multi-drug resistance of cancer cells. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - SM-IMPORT - - - ERC-2014-STG - - - 638536 - - - - - FUNDACION CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III - - - EUR 170 121,60 - - - Molecular mechanisms regulating cardiovascular remodeling by Adamts1 - - - EUR 170 121,60 - - - Spain - - - Research Organisations - - Professor Redondo’s group has recently identified Adamts1 as one of the major mediators in vascular wall remodeling. They showed that Adamts1+/-, Adamts1-/- and KD-Adamts1 mice present aortic dilation, aneurysms, medial - degeneration and hypotension, leading to the hypothesis that Adamts1 deficiency results in a new familial form of thoracic aortic aneurysm (FTAAD) potentially relevant in human aortic disease. They have also found that nitric oxide synthase (NOS) - inhibitors reverse aortic dilation and medial degeneration in Marfan mice and Adamts1-deficient mice. The objective of my project is to study the molecular mechanisms mediating these aortic diseases in mice, and to specifically assess the role of - nitric oxide (NO) and related signaling pathways, including those of Adamts1 and its substrates, in the medial degeneration and aortic dilation in both mouse models. I plan to identify potential targets common to both aortopathies and analyze them in - patients with syndromic and non-syndromic aortic diseases. I think this project has a strong potential to identify therapeutic targets and prognostic or diagnostic markers for human cardiovascular diseases that constitute one of the major causes of - mortality worldwide. - - 2018-05-31, ongoing project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - MERC - - - H2020-MSCA-IF-2015 - - - 703561 - - - - - ECOLE CENTRALE DE LYON - UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II. - KATHOLIEKE UNIVERSITEIT LEUVEN - UNIVERSITY OF BRISTOL - UNIVERSITE DE FRANCHE-COMTE - - - EUR 3 131 359,47 - - - VIbro-acoustics of PERiodic media - - - EUR 3 131 359,47 - - - France - Italy - Belgium - United Kingdom - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - VIPER is a European Joint Doctorate network focused on research in VIbroacoustic of PERiodic media. Structural periodic - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-EJD - Marie Skłodowska-Curie Innovative Training Networks (ITN-EJD) - - - MSCA-ITN-EJD - European Joint Doctorates - - - France - - - VIPER - - - H2020-MSCA-ITN-2015 - - - 675441 - - - - - HELMHOLTZ ZENTRUM POTSDAM DEUTSCHESGEOFORSCHUNGSZENTRUM GFZ - FUTUREWATER BV - ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA - TECHNISCHE UNIVERSITAET WIEN - GECOSISTEMA SRL - STICHTING DELTARES - UNIVERSITY OF BRISTOL - MIDDLESEX UNIVERSITY HIGHER EDUCATION CORPORATION - UMWELTBUNDESAMT - HR WALLINGFORD LIMITED - - - EUR 3 884 131,08 - - - A Large-Scale Systems Approach to Flood Risk Assessment and Management - - - EUR 3 884 131,08 - - - Germany - Netherlands - Italy - Austria - Italy - Netherlands - United Kingdom - United Kingdom - Germany - United Kingdom - - - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - - Flood risk systems are characterised by physical and socio-economic processes acting at different space-time scales, by non-stationary and non-linear behaviour, and by a significant degree of interdependence between processes. - This may lead to surprising developments and unanticipated side effects of risk reduction measures. A novel systems approach is needed that captures this dynamics and accounts for the interactions of the system components. We propose the ETN - SYSTEM-RISK which aims at developing this systems approach for large spatial scales, from large river basins to the European scale. The research concept of SYSTEM-RISK builds upon the entire risk chain, from the source of hazard to consequences, and - analyses the interactions and temporal dynamics in flood risk systems. In this way, the linear risk chain is replaced by a more realistic approach with interdependent links. SYSTEM-RISK exposes early-stage researchers (ESR) to all knowledge domains - along the risk chain, and gives them, at the same time, the opportunity to build specific research profiles. The interdisciplinary setting and the focus on interactions and spatio-temporal dynamics of risk system will expand the mental models and - lead to a new generation of creative scientists, able to transfer their systems perspective from flood risk systems to other fields. We bring together internationally leading groups in flood research with institutions from the non-academic main - sectors exploiting flood research – consultancy, insurance industry and governmental sector. Close interaction will support the ESRs in developing trans-disciplinary skills with an understanding of both fundamental science and application. - SYSTEM-RISK will deliver a suite of methods and tools for assessing and managing flood risk across large regions. This will be of highest importance for the EU Flood Directive and Strategy on Adaptation for Climate Change due to the EU’s key role in - dealing with risks transcending national borders. - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - SYSTEM-RISK - - - H2020-MSCA-ITN-2015 - - - 676027 - - - - - EUROPEAN SOCIAL SURVEY EUROPEAN RESEARCH INFRASTRUCTURE CONSORTIUM - EUROPEAN RESEARCH INFRASTRUCTURE CONSORTIUM FOR THE SURVEY OF HEALTH, AGEING AND RETIREMENT IN EUROPE - CESSDA AS - KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW - STICHTING KATHOLIEKE UNIVERSITEIT BRABANT - UNIVERSITEIT VAN AMSTERDAM - - - EUR 8 494 397 - - - Synergies for Europe's Research Infrastructures in the Social Sciences - - - EUR 8 884 397 - - - United Kingdom - Germany - Norway - Netherlands - Netherlands - Netherlands - - - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Europe is facing huge socio-economic challenges: an economic crisis with a young generation in search of jobs, population ageing potentially straining inclusion and innovation of our societies, climate change with its - pressures to redesign energy, transport and housing patterns, just to name some of the most urgent “Grand Challenges”. SERISS brings together three research infrastructures in the social sciences: the European Social Survey (ESS), the Survey for - Health Ageing and Retirement in Europe and the Consortium of European Social Science Data Archives (CESSDA). Also involved in SERISS are non-ESFRI research infrastructures: GGP - Generations and Gender Programme; EVS - European Values Survey and the - WageIndicator Survey. - - - 2019-06-30, ongoing project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-4-2014-2015 - Implementation and operation of cross-cutting services and solutions for clusters of ESFRI and other relevant research infrastructure initiatives - - - RIA - Research and Innovation action - - - United Kingdom - - - SERISS - - - H2020-INFRADEV-1-2014-1 - - - 654221 - - - - - KOBENHAVNS UNIVERSITET - UNIVERSITEIT VAN AMSTERDAM - LEIBNIZ-INSTITUT FUR GEMUSE- UND ZIERPFLANZENBAU GROSSBEEREN/ERFURT EV - AARHUS UNIVERSITET - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - INOQ GmbH - UNIWERSYTET MIKOLAJA KOPERNIKA W TORUNIU - AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH - DLF SEEDS AS - TECHNISCHE UNIVERSITAET GRAZ - ABITEP GMBH - ACIB GmbH - - - EUR 3 907 754,64 - - - Boosting plant-Endophyte STability, compatibility and Performance Across ScaleS - - - EUR 3 907 754,64 - - - Denmark - Netherlands - Germany - Denmark - Spain - Germany - Poland - Austria - Denmark - Austria - Germany - Austria - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - - We need to increase the crop yield while reducing pesticide and use of inorganic fertiliser to meet the challenges of world population growth and climate change. Plant endophytic microorganisms can improve plant yield and - enhance plant tolerance to abiotic stress as well as to pathogens under experimental conditions, but these effects are often not sufficiently stable for practical application. How do we boost the stability and reliability of the positive effects of - endophytes on plants? We need to understand the genetic basis of beneficial interactions between crops and endophytes and extent this basis exhibits phenotypic plasticity at all interaction levels from the cellular to the field environment. This - requires increasing our knowledge of the molecular mechanisms underlying the effects of endophytes, including intra and inter-kingdom exchange and distribution of resources (nutrients), signalling and possibly regulation between and inside the - partners, the mutual induced production of secondary metabolites and the environmental cues which influence crop-endophyte interactions. The genetic variation and its plasticity in host and microbe will be exploited in to establish crop breeding and - inoculum production processes for boosting the establishment and stability of plant-microbe mutualisms to benefit crop development, stress tolerance, pathogen resistance and quality. In this project we will provide fundamental biological as well as - practical knowledge about interactions between endophytes and plants. This improved understanding will pave the way for increased use of endophytes to improve sustainability and plant productivity in a reliable way. The participants in this project - comprise many of the key institutions and industries working with these problems and provide a uniquely strong consortium to address the key issues. Furthermore, the consortium will train a new generation of scientists who have the insight and skills - to continue this task in their careers. - - 2019-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Denmark - - - BestPass - - - H2020-MSCA-ITN-2015 - - - 676480 - - - - - STAB VIDA INVESTIGACAO E SERVICOS EM CIENCIAS BIOLOGICAS LDA - UNIVERSITY OF HULL - GENOLOGICA MEDICA SL - INSTITUT ZA ONKOLOGIJU I RADIOLOGIJU SRBIJE - GENETIKS SAGLIK HIZMETLERI TICARETLIMITED SIRKETI - UNIWERSYTET JAGIELLONSKI - FUNDACAO DA FACULDADE DE CIENCIAS DA UNIVERSIDADE DE LISBOA FP - FCIENCIAS.ID - ASSOCIACAO PARA A INVESTIGACAO E DESENVOLVIMENTO DE CIENCIAS - UNIVERSIDAD SAN MARTIN DE PORRES ASOCIACION - Institut Pasteur Du Maroc - UNIVERSITE HASSAN II DE CASABLANCA - PARSEQ LAB CO LTD - FEDERAL UNIVERSITY OF AGRICULTURE ABEOKUTA - RESPUBLIKA ONKOLOGIYA ILMIY MARKAZI - UNIVERSITY OF TECHNOLOGY SYDNEY - Sloan-Kettering Institute for Cancer Research CORPORATION - MILLI ONKOLOGIYA MERKEZI - - - EUR 976 500 - - - Blood test for clinical therapy guidance of non-small cell lung cancer patients - - - EUR 1 039 500 - - - Portugal - United Kingdom - Spain - Serbia - Turkey - Poland - Portugal - Portugal - Peru - Morocco - Morocco - Russia - Nigeria - Uzbekistan - Australia - United States - Azerbaijan - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - - Lung cancer is the most common cancer worldwide. NSCLC alone make up about 75% of all lung cancers and most hospitals currently test all NSCLC patients for EGFR mutations (pharmacogenomics) for treatment decision (personalised - medicine) – i.e., patients with mutation(s) in EGFR gene should receive a EGFR-Tyrosine Kinase Inhibitor (TKI) drug (e.g. afitinib) treatment; while those that do not present mutations in such gene, should be treated with chemotherapy. Currently, the - laboratories use PCR and Sanger sequencing technologies to perform the EGFR analysis from tumour biopsies - Fixed Paraffin Embedded (FFPE) samples. Still, some patients (e.g., 30% in UK) may never get histological confirmation because they are too - sick to make a biopsy. Furthermore, the results obtained with current methods still present low quality, mainly due to poor quality/low yield of DNA extracted from FFPE samples. The FP7 LungCARD project (www.lungcard.eu) has developed and - demonstrated a LungCARD system - an automatic system composed by microfluidic chip and chip analyser - that allows to capture circulating tumour cells (CTCs) from blood samples, amplify by multiplex PCR and detect EGFR mutations, including also a - software for data analysis and report. Although this new blood test has proven to be faster, cost-effective and human error-free, the detection of somatic mutations in EGFR gene at frequencies lower than 20% is still a weak point. - - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Portugal - - - LungCARD - - - H2020-MSCA-RISE-2016 - - - 734790 - - - - - ATOS SPAIN SA - TECHNISCHE UNIVERSITAET BERLIN - UNIVERSITE DE STRASBOURG - STIFTELSEN SINTEF - BCAM - BASQUE CENTER FOR APPLIED MATHEMATICS - SZECHENYI ISTVAN UNIVERSITY - Konrad-Zuse-Zentrum für Informationstechnik Berlin - FUNDACION PUBLICA GALLEGA CENTRO TECNOLOGICO DE SUPERCOMPUTACION DE GALICIA - KUNGLIGA TEKNISKA HOEGSKOLAN - STICHTING EUROPEAN SERVICE NETWORK OF MATHEMATICS FOR INDUSTRY AND INNOVATION - - - EUR 2 435 064,50 - - - Mathematical Modelling, Simulation and Optimization for Societal Challenges with Scientific Computing - - - EUR 2 435 064,50 - - - Spain - Germany - France - Norway - Spain - Hungary - Germany - Spain - Sweden - Netherlands - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Other - - The challenges of society show rising complexity and their solution process increasingly requires a holistic approach. It is necessary to provide decision makers with tools that allow long-term risk analysis, improvements or - even optimization and control. - - - 2018-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.3."> - - - EINFRA-22-2016 - User-driven e-infrastructure innovation - - - RIA - Research and Innovation action - - - Spain - - - MSO4SC - - - H2020-EINFRA-2016-1 - - - 731063 - - - - - TECHNISCHE UNIVERSITEIT EINDHOVEN - TECHNISCHE UNIVERSITAET GRAZ - TECHNISCHE UNIVERSITEIT DELFT - UNIVERSITAET BIELEFELD - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - UNIVERSITY OF HULL - MICROINNOVA ENGINEERING GMBH - - - EUR 3 896 827,50 - - - Catalyst Cascade Reactions in ‘One-Flow’ within a Compartmentalized, Green-Solvent ‘Digital Synthesis Machinery’ – End-to-End Green Process Design for Pharmaceuticals - - - EUR 3 896 827,50 - - - Netherlands - Austria - Netherlands - Germany - France - United Kingdom - United Kingdom - Austria - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - "ONE-FLOW translates ‘vertical hierarchy’ of chemical multistep synthesis with its complex machinery into self-organising ‘horizontal hierarchy’ of a compartmentalized flow reactor system – a biomimetic digital flow cascade - machinery with just one reactor passage. To keep horizontal hierarchy manageable, orthogonality among the consecutive reactions needs to be increased. The winning point of nature is to have invented catalytic cascades. ONE-FLOW will uplift that by - enabling the best bio- and chemocatalysts working hand in hand. 4 synthetic flow cascades ('metabolic pathways’) and 1 flow cascade driven by automated intelligence ('signaling pathway') will produce 4 Top-list 2020 drugs. ‘The Compartmentalized - Smart Factory’ will develop organic, inorganic, and mechanical compartmentalization. ‘The Green-Solvent Spaciant Factory’ will fluidically allow the use of interim reaction spaces (spaciants). ‘The Systemic Operations Factory’ will aim at full - orthogonality using data-base guided ultimate process harmonization. ‘The Digital Machine-to-Machine Factory’ will alter the landscape of chemical synthesis by virtue of the ""Internet of Chemical Things"". Automated machine-to-machine data transfer - enables relegation of process monitoring to central computer systems under the oversight of chemists. ‘The Fully Continuous Integrated Factory’ will develop a commercial platform technology under the auspices of sustainability-driven process-design - evaluation, making amenable the new kind of processing to all chemists. ONE-FLOW has massive impact potential: i) 38 billion Euro production cost saving; ii) 300 million EUR cost saving per drug; iii) address diseases with 500 billion Euro medication - costs; iv) increase market share of emerging high-tech SME players by 10% in 10 years; v) open new windows of opportunity (personalized medicine) with 200-500 million Euro per disease; and vi) achieve 40% female share on a senior scientist level - (ONE-FLOW: 34% senior, 57% junior)." - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-01-2016-2017 - FET-Open research and innovation actions - - - RIA - Research and Innovation action - - - Netherlands - - - One-Flow - - - H2020-FETOPEN-1-2016-2017 - - - 737266 - - - - - UNIVERSITEIT VAN AMSTERDAM - UNIVERSITY COLLEGE LONDON - INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK - BAYERISCHE AKADEMIE DER WISSENSCHAFTEN - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - UNIVERSITEIT LEIDEN - SCIENCE AND TECHNOLOGY FACILITIES COUNCIL - ALLINEA SOFTWARE LIMITED - CBK SCI CON LIMITED - SAINT PETERSBURG NATIONAL RESEARCH UNIVERSITY OF INFORMATION TECHNOLOGIES, MECHANICS AND OPTICS - BRUNEL UNIVERSITY LONDON - - - EUR 3 942 885 - - - Computing Patterns for High Performance Multiscale Computing - - - EUR 4 122 864,36 - - - Netherlands - United Kingdom - Poland - Germany - Germany - Netherlands - United Kingdom - United Kingdom - United Kingdom - Russia - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Multiscale phenomena are ubiquitous and they are the key to understanding the complexity of our world. Despite the significant progress achieved through computer simulations over the last decades, we are still limited in our - capability to accurately and reliably simulate hierarchies of interacting multiscale physical processes that span a wide range of time and length scales, thus quickly reaching the limits of contemporary high performance computing at the tera- and - petascale. Exascale supercomputers promise to lift this limitation, and in this project we will develop multiscale computing algorithms capable of producing high-fidelity scientific results and scalable to exascale computing systems. Our main - objective is to develop generic and reusable High Performance Multiscale Computing algorithms that will address the exascale challenges posed by heterogeneous architectures and will enable us to run multiscale applications with extreme data - requirements while achieving scalability, robustness, resiliency, and energy efficiency. Our approach is based on generic multiscale computing patterns that allow us to implement customized algorithms to optimise load balancing, data handling, fault - tolerance and energy consumption under generic exascale application scenarios. We will realise an experimental execution environment on our pan-European facility, which will be used to measure performance characteristics and develop models that can - provide reliable performance predictions for emerging and future exascale architectures. The viability of our approach will be demonstrated by implementing nine grand challenge applications which are exascale-ready and pave the road to unprecedented - scientific discoveries. Our ambition is to establish new standards for multiscale computing at exascale, and provision a robust and reliable software technology stack that empowers multiscale modellers to transform computer simulations into - predictive science. - - 2018-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.2."> - - - FETHPC-1-2014 - HPC Core Technologies, Programming Environments and Algorithms for Extreme Parallelism and Extreme Data Applications - - - RIA - Research and Innovation action - - - Netherlands - - - ComPat - - - H2020-FETHPC-2014 - - - 671564 - - - - - UNIVERSITY COLLEGE LONDON - UNIVERSITEIT VAN AMSTERDAM - THE UNIVERSITY OF EDINBURGH - BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION - SURFSARA BV - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - UNIVERSITE DE GENEVE - THE UNIVERSITY OF SHEFFIELD - CBK SCI CON LIMITED - UNIVERSIDAD POMPEU FABRA - LIFETEC GROUP BV - ACELLERA LABS SL - EVOTEC AG* - BULL SAS - Janssen Pharmaceutica NV - - - EUR 4 938 215,75 - - - A Centre of Excellence in Computational Biomedicine - - - EUR 4 938 216,25 - - - United Kingdom - Netherlands - United Kingdom - Spain - Netherlands - United Kingdom - Switzerland - United Kingdom - United Kingdom - Spain - Netherlands - Spain - Germany - France - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - This Centre of Excellence will advance the role of computationally based modelling and simulation within biomedicine. Three related user communities lie at the heart of the CoE: academic, industrial and clinical researchers - who all wish to build, develop and extend such capabilities in line with the increasing power of high performance computers. Three distinct exemplar research areas will be pursued: cardiovascular, molecularly-based and neuro-musculoskeletal medicine. - - 2019-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.3."> - - - EINFRA-5-2015 - Centres of Excellence for computing applications - - - RIA - Research and Innovation action - - - United Kingdom - - - CompBioMed - - - H2020-EINFRA-2015-1 - - - 675451 - - - - - UNIVERSITETET I OSLO - FREIE UNIVERSITAET BERLIN - FONDATION NATIONALE DES SCIENCES POLITIQUES - INSTITUT FUER HOEHERE STUDIEN - INSTITUTE FOR ADVANCED STUDIES - INSTITUTE OF SOCIOLOGY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC PUBLIC RESEARCH INSTITUTION - UNIWERSYTET JAGIELLONSKI - UNIVERSITEIT ANTWERPEN - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - UNIVERSITEIT TWENTE - - - EUR 3 873 718,80 - - - The Post-crisis Legitimacy of the European UnionEuropean Training Network - - - EUR 3 873 718,80 - - - Norway - Germany - France - Austria - Czech Republic - Poland - Belgium - United Kingdom - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Is there a crisis in the legitimacy of the European Union? That research question is timely and important. Investigating it is also an ideal way of training research leaders of tomorrow to rethink our assumptions about the - study of legitimate political order. Whilst, however, the financial crisis has raised new questions about the legitimacy of the EU, existing theories of legitimacy crises are largely based on single-state political systems. New theory is, therefore, - needed to understand what would count as legitimacy crises in the case of a non-state political system such as the EU. PLATO’s (The Post-Crisis Legitimacy of the EU) ESRs will work together as a team to build new theory from 15 investigations into - different standards and actors with whom the EU may need to be legitimate. ESRs will go well beyond the state-of-the-art by building a theory of legitimacy crisis in the EU from a uniquely interdisciplinary understanding of how democracy, power, law, - economies and societies all fit together with institutions within and beyond the state to affect the legitimacy of contemporary political order. By developing the analytical tools needed to understand a core predicament in which the EU may both need - to develop legitimate forms of political power beyond the state and find those forms of power hard to achieve, PLATO will train ESRs with the conceptual clarity needed to define new research questions at the very frontiers of their disciplines and - the methodological skills needed to research those questions. They will also be prepared for careers in the non-academic sector (policy-advice, consulting, civil society, European institutions and expert bodies). PLATO’s ambitious cross-university, - cross-country and cross-sectoral programme of research training, supervision and secondments will pool resources from a unique network of 9 research-intensive universities and 11 non-academic partners who are themselves key users of state-of-the-art - social science research. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Norway - - - PLATO - - - H2020-MSCA-ITN-2016 - - - 722581 - - - - - UNIVERSIDAD CARLOS III DE MADRID - UNIVERSIDAD DE ZARAGOZA - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - UNIVERSITEIT VAN AMSTERDAM - AALTO-KORKEAKOULUSAATIO - UNIVERSITAT DE VALENCIA - - - EUR 2 663 237,25 - - - Bridging the gap: from Individual Behaviour to the Socio-tEchnical MaN - - - EUR 2 663 237,75 - - - Spain - Spain - United Kingdom - United Kingdom - Netherlands - Finland - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Developing models of real-world societal scenarios and systems is a key topic in the research agenda of social sciences, but is hindered by the lack of controlled experimentation with large groups of people. IBSEN will provide - a breakthrough by building a repertoire of human behaviour in large (1000+ persons) structured groups using controlled experiments. To that end, we will develop a novel setup for large groups of people that will provide an experimental protocol, the - necessary software and analytical tools to allow us to deal with thousands of people at the same time. We will apply our setup to specific research questions, focusing on novel phenomenology that may arise in large systems as compared to typical - smaller ones, to find the rules that govern human behaviour in those cases, including the influence of social context and individual identity on them. We will assess our approach by building a model of human interaction in groups based on the - behavioural rules we have found. The project requires a high-degree of interdisciplinarity; accordingly, the team consists of physicists, economists, social psychologists, and computer scientists. On the other hand, this is a high-risk project, as - the experimental design may prove unfeasible for really large systems and extracting meaningful data from the participants’ actions may not be possible. Notwithstanding, encouraging results in some pilot studies run by partners underpin the - scientific feasibility of the concept and approach. If successful, researchers will be able to build on our findings to develop a human behaviour simulator, a technology providing a basis for socio-economic simulations that would radically change - many fields, from robotics to economics, with technological and societal impacts, including policy-making in socially pressing issues. We will thus lay the foundations to kick start a new way of doing social science for the problems arising in a - technologically highly connected society. - - 2018-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-1-2014 - FET-Open research projects - - - RIA - Research and Innovation action - - - Spain - - - IBSEN - - - H2020-FETOPEN-2014-2015-RIA - - - 662725 - - - - - UNIVERSITEIT VAN AMSTERDAM - - - EUR 165 598,80 - - - 'Feeling European'. The Visual Construction of EU Identity. - - - EUR 165 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - European Visual Identity - Summary - - 2017-07-31, Grant Agreement terminated - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - EVI - - - H2020-MSCA-IF-2014 - - - 660793 - - - - - UNIVERSITEIT VAN AMSTERDAM - CARDIFF UNIVERSITY - MAAT France - CONSIGLIO NAZIONALE DELLE RICERCHE - UNIVERSIDAD DE ALCALA - MARTIN-LUTHER-UNIVERSITAET HALLE-WITTENBERG - - - EUR 1 005 875 - - - GLOBal Infrastructures for Supporting Biodiversity research - - - EUR 1 005 875 - - - Netherlands - United Kingdom - France - Italy - Spain - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Biodiversity and ecosystem research is addressing the grand societal challenge to predict the biosphere under global environmental change. To advance scientific progress in understanding the complexity of natural systems it is - required that supporting research infrastructures cooperate globally to serve the essential data at different temporal and spatial scales. This includes providing the capabilities to process big and massive datasets. GLOBIS-B is a global cooperation - of world-class research infrastructures with a focus on targeted services to support frontier research that deals with predicting the biosphere and measuring the indicators of biodiversity change. The project brings key scientists together with - global research infrastructure operators and legal interoperability experts to address research needs and infrastructure services underpinning the concept of Essential Biodiversity Variables (EBVs). EBVs were proposed by the GEO Biodiversity - Observation Network (GEO BON) and are a prerequisite for understanding biodiversity and ecosystem change. Integrated scientific and technical workshops will identify the required primary data, analysis tools, methodologies etc. to develop an - infrastructure development agenda for computing EBVs and to explore the discovery of required and interoperable data at larger spatial and temporal scales. Applications of common standards and workflows that are ‘self-documenting’ and openly shared - facilitate international cooperation, and realistic and pragmatic solutions are explored to streamline the legal bottlenecks for the reciprocal use of data and software tools from different origins. Solutions should be workable for both the - scientific communities and the cooperating research infrastructures, especially in regard to achieving direct machine-machine interactions. The interaction with national, supra-national and global policy bodies contributes to potential refinements of - general policies supporting legal interoperability. - - 2018-05-31, ongoing project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.3.2."> - - - INFRASUPP-6-2014 - International cooperation for research infrastructures - - - CSA - Coordination and support action - - - Netherlands - - - GLOBIS-B - - - H2020-INFRASUPP-2014-2 - - - 654003 - - - - - STIFTUNG DEUTSCHES ELEKTRONEN-SYNCHROTRON DESY - ISTITUTO NAZIONALE DI FISICA NUCLEARE - CONSIGLIO NAZIONALE DELLE RICERCHE - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSITY OF STRATHCLYDE - ASSOCIACAO DO INSTITUTO SUPERIOR TECNICO PARA A INVESTIGACAO E DESENVOLVIMENTO - SCIENCE AND TECHNOLOGY FACILITIES COUNCIL - Société civile SYNCHROTRON SOLEIL - THE UNIVERSITY OF MANCHESTER - THE UNIVERSITY OF LIVERPOOL - AGENZIA NAZIONALE PER LE NUOVE TECNOLOGIE, L'ENERGIA E LO SVILUPPO ECONOMICO SOSTENIBILE - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA - UNIVERSITAET HAMBURG - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 2 999 900 - - - Proposal for a Horizon 2020 Design Study on the “European Plasma Research Accelerator with eXcellence In Applications“ (EuPRAXIA) - - - EUR 2 999 900 - - - Germany - Italy - Italy - France - United Kingdom - Portugal - United Kingdom - France - United Kingdom - United Kingdom - Italy - France - Italy - Germany - United Kingdom - United Kingdom - - - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - EuPRAXIA will produce a conceptual design report for the worldwide first 5 GeV plasma-based accelerator with industrial beam quality and user areas. EuPRAXIA is the required intermediate step between proof-of-principle - experiments and ground-breaking, ultra-compact accelerators for science, industry, medicine or the energy frontier (“plasma linear collider”). The study will design accelerator technology, laser systems and feedbacks for improving the quality of - plasma-accelerated beams. Two user areas will be developed for a novel Free Electron Laser and High Energy Physics detector science. An implementation model will be proposed, including a comparative study of possible sites in Europe, a cost estimate - and a model for distributed construction and installation at one central site. EuPRAXIA will be a new large research infrastructure with an estimated footprint of about 250 m. If the design study is approved, then it will lay the foundation for a - possible decision on construction in 2020. - - - 2019-10-31, ongoing project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-1-2014 - Design studies - - - RIA - Research and Innovation action - - - Germany - - - EuPRAXIA - - - H2020-INFRADEV-1-2014-1 - - - 653782 - - - - - UNIVERSITE PARIS 13 - - - EUR 185 076 - - - Collective personalities: from individuals to groups, and back - - - EUR 185 076 - - - France - - - Higher or Secondary Education Establishments - - Many organisms, including humans, group together and perform collective actions such as birds forming coordinated flocks to evade predators, forage or roost. Some, as social insects, have evolved complex societies in which the - unit of selection is not the individual, as in most vertebrates, but the colony. Yet, in both there is evidence of consistent behavioural variability among both individuals and groups. The study of collective behaviour - coordinated actions resulting - in emergent properties at the group level - and the study of animal personality - between individual differences that are consistent over time and contexts - have progressed tremendously in the last two decades and are converging in their search for - the link between individuality and collectivity, a fundamental and timely issue in biology. The GROUPIND project aims to investigate the relationship between individual personality and group personality by using ants and starlings as study organisms, - both of which showing distinct collective behaviour and marked individual behavioural variability. The project will use a comparative approach to address the following objectives: (1) To characterize, also upon experimental manipulation, the - composition of personalities in the group and understand how this relates to personality at the group level. Are group personalities an average of individual personalities within the group? Do they result from different distributions of individual - personalities? Are there keystone individuals that exert a disproportionate influence on the group personality? (2) To understand how diversity of individual personalities contributes to decision making and to the ecological success at the group - level, and how this would feed back at the individual level. By bridging two major fields of study, this project will shed new light on the ability of groups to function effectively, unravelling the consequences that personality differences can exert - on social life and its evolution. - - 2017-09-30, Grant Agreement terminated - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - France - - - GROUPIND - - - H2020-MSCA-IF-2014 - - - 659106 - - - - - CENTRO DE NEUROCIENCIAS E BIOLOGIACELULAR ASSOCIACAO - CONSIGLIO NAZIONALE DELLE RICERCHE - Faculdade de Farmácia da Universidade de Lisboa - HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - UNIVERSITA DEGLI STUDI DI BARI ALDO MORO - UNIVERSIDADE DO PORTO - INSTYTUT BIOLOGII DOSWIADCZALNEJ IM. M. NENCKIEGO POLSKIEJ AKADEMII NAUK - KING'S COLLEGE LONDON - MEDIAGNOST GESELLSCHAFT FUR FORSCHUNG UND HERSTELLUNG VON DIAGNOSTIKA GMBH - ASSOCIACAO PROTECTORA DOS DIABETICOS DE PORTUGAL - OROBOROS INSTRUMENTS GmbH - MICRO-BIOLYTICS GMBH - - - EUR 454 500 - - - mitoFOIE GRAS: Non-invasive Profiling of Mitochondrial Function in Non-Alcoholic Fatty Liver Disease - - - EUR 454 500 - - - Portugal - Italy - Portugal - Germany - Spain - Italy - Portugal - Poland - United Kingdom - Germany - Portugal - Austria - Germany - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - "Non-Alcoholic Fatty Liver Disease (NAFLD), including its more pathologic consequence, non-alcoholic steatohepatitis (NASH), is believed to be the most common chronic liver disease worldwide, affecting between 6 to 37% of the - population. NAFLD is a so called ‘silent killer’, as clinical symptoms only surface at late stages of the disease, when it is no longer treatable: untreated, NAFLD/NASH can lead to cirrhosis and hepatocellular carcinoma, culminating in liver failure. - Currently the best method of diagnosing and staging the disease is liver biopsy, a costly, invasive and somewhat risky procedure, not to mention unfit for routine assessment. Besides, no therapeutic consensus exists for NAFLD/NASH treatment. - - 2021-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Portugal - - - mtFOIE GRAS - - - H2020-MSCA-RISE-2016 - - - 734719 - - - - - KING'S COLLEGE LONDON - - - EUR 183 454,80 - - - Investigating Natural, Historical, And Institutional Transformations - Cities - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The overall aim of INHAbIT is to improve understandings of the dynamics of water service provision in urban environments in the global South. In particular, INHAbIT will explore historical processes and transformations that - have shaped water service configurations, the politics of socio-technical urban water supply systems and the socio-ecological processes shaping the urban waterscape. INHAbIT is innovative in that it takes an interdisciplinary approach and aims at - developing new methodologies and conceptual approaches. To this aim, INHAbIT has identified three objectives, which combine theoretical, methodological and empirical elements: undertake a theoretical synthesis that brings urban political ecology - perspectives into engagement with institutional bricolage; explore and test innovative methodologies for tracking informality and investigating socio-natural processes; undertake empirical work and building up a robust body of rigorously researched - historical and qualitative data on natural, historical and institutional transformations that have shaped and continuously re-shape water service realities in Lilongwe (Malawi) and Maputo (Mozambique). While taking a critical approach, INHAbIT is - also cognizant of the needs of policy makers and practitioners for solutions that work for serving with adequate water a growing population. The researcher, Maria Rusca, will explore the implications of INHAbIT’s research findings for policy and - practice and disseminate accordingly. INHAbIT, thus, will be both scientifically innovative and policy relevant. - - 2017-09-13, closed project - - - 2015-09-14 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - INHABIT Cities - - - H2020-MSCA-IF-2014 - - - 656738 - - - - - UNIVERSITEIT VAN AMSTERDAM - UNIVERSITETET I STAVANGER - UNIVERSITY OF SOUTHAMPTON - FTK FORSCHUNGSINSTITUT FUR TELEKOMMUNIKATION UND KOOPERATION EV - STICHTING EGI - ENGINEERING - INGEGNERIA INFORMATICA SPA - INMARK ESTUDIOS Y ESTRATEGIAS SA - INMARK EUROPA SA - - - EUR 2 500 000 - - - Education for Data Intensive Science to Open New science frontiers - - - EUR 2 500 000 - - - Netherlands - Norway - United Kingdom - Germany - Netherlands - Italy - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The EDISON project will focus on activities to establish the new profession of ' Data Scientist', following the emergence of Data Science technologies (also referred to as Data Intensive or Big Data technologies) which changes - the way research is done, how scientists think and how the research data are used and shared. This includes definition of the required skills, competences framework/profile, corresponding Body Of Knowledge and model curriculum. It wil develop a - sustainability/business model to ensure a sustainable increase of Data Scientists, graduated from universities and trained by other professional education and training institutions in Europe. - - - 2017-08-31, closed project | - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.2.2."> - - - INFRASUPP-4-2015 - New professions and skills for e-infrastructures - - - CSA - Coordination and support action - - - Netherlands - - - EDISON - - - H2020-INFRASUPP-2015-1 - - - 675419 - - - - - UNIVERSITY OF BATH - RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN - FONDAZIONE BRUNO KESSLER - UNIVERSITA DEGLI STUDI DI GENOVA - MAPLESOFT EUROPE LIMITED - UNIVERSITE DE LORRAINE - COVENTRY UNIVERSITY - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - UNIVERSITAET KASSEL - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - UNIVERSITAT LINZ - - - EUR 499 603,75 - - - SC-square - Satisfiability Checking and Symbolic Computation: uniting two communities to solve real problems - - - EUR 499 603,75 - - - United Kingdom - Germany - Italy - Italy - United Kingdom - France - United Kingdom - United Kingdom - Germany - Germany - Austria - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Higher or Secondary Education Establishments - - The use of advanced methods to solve practical and industrially relevant problems by computers has a long history. Whereas Symbolic Computation is concerned with the algorithmic determination of exact solutions to complex - mathematical problems, more recent developments in the area of Satisfiability Checking tackle similar problems but with different algorithmic and technological solutions. - - - 2018-08-31, ongoing project | - - - 2016-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-3-2015 - Coordination and Support Activities - - - CSA - Coordination and support action - - - United Kingdom - - - SC-square - - - H2020-FETOPEN-2015-CSA - - - 712689 - - - - - POLITECNICO DI TORINO - UNIVERSITY OF BRISTOL - ECOLE NATIONALE SUPERIEURE D'ARTS ET METIERS - GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER - LUXEMBOURG INSTITUTE OF SCIENCE AND TECHNOLOGY - ELAN-AUSY GMBH - - - EUR 3 095 280,36 - - - FULLY INTEGRATED ANALYSIS, DESIGN, MANUFACTURING AND HEALTH-MONITORING OF COMPOSITE STRUCTURES - - - EUR 3 095 280,36 - - - Italy - United Kingdom - France - Germany - Luxembourg - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Composite structures are massively exploited in many engineering fields. For instance, the state-of-the-art civil aircraft (B787 and A350) are mostly made of composite materials. The design of composites leads to challenging - tasks since those competencies that stemmed from the adoption of metallic materials are often inadequate for composites. Insights on many different disciplines and tight academic/industrial cooperation are required to fully exploit composite - structure capabilities. The skills and the employability of young researchers increase to a great extent through an interdisciplinary and intersectoral training. The existing training schemes are often based on specific themes and disciplines rather - than on a broad interdisciplinary and academic-industrial integrated approach. The main aim and novelty of this project is the creation of a multidisciplinary, intersectoral and international research training network based on a strong academic basis - and industrial partnerships for a new generation of top talented young researchers that will work in the European academic and industrial scenarios. The multidisciplinary features are guaranteed by the presence of 7 universities, 1 research centre - and 1 industry. The intersectoral approach will be pursued by including secondments and specific industrial training requirements in each individual project. The consortium is composed by partners from 8 countries. OTC partners were included for - secondment and training opportunities; they were chosen on the basis of their expertise and to enhance the internationality features of the training. Their presence is seen as an opportunity for the European partners and researchers to strengthen - competencies. The full spectrum of the design of composite structures will be dealt with - manufacturing, health-monitoring, failure, modelling, multiscale approaches, testing, prognosis and prognostic - to develop integrated analysis tools to - improve the design of composites. - - 2019-05-31, ongoing project | - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Italy - - - FULLCOMP - - - H2020-MSCA-ITN-2014 - - - 642121 - - - - - STICHTING KATHOLIEKE UNIVERSITEIT - STICHTING KARAKTER - UNIVERSITY OF LEICESTER - KING'S COLLEGE LONDON - KAROLINSKA INSTITUTET - UNIVERSITAT DE BARCELONA - BRAINGAZE SL - FUNDACIO HOSPITAL UNIVERSITARI VALL D'HEBRON - INSTITUT DE RECERCA - EUROFINS MEDIGENOMIX GMBH - JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN - UNIVERSITAETSKLINIKUM WUERZBURG - KLINIKUM DER BAYERISCHEN JULIUS-MAXIMILIANS-UNIVERSITAT - UNIVERSITETET I BERGEN - FUNDACIO CENTRE DE REGULACIO GENOMICA - - - EUR 3 913 940,43 - - - Mastering skills in the training Network for attention deficit hyperactivity and autism spectrum Disorders - - - EUR 3 913 940,43 - - - Netherlands - Netherlands - United Kingdom - United Kingdom - Sweden - Spain - Spain - Spain - Germany - Germany - Germany - Norway - Spain - - - Higher or Secondary Education Establishments - Other - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - Attention deficit/hyperactivity disorder (ADHD) and autism spectrum disorders (ASD) are frequent, chronic and highly heritable neurodevelopmental disorders. Despite their societal importance, progress in understanding disease - biology has been slow and no curative treatment options are available. - - 2018-12-31, ongoing project | - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Netherlands - - - MiND - - - H2020-MSCA-ITN-2014 - - - 643051 - - - - - PIN SOC.CONS. A R.L. - SERVIZI DIDATTICI E SCIENTIFICI PER L UNIVERSITA DI FIRENZE - INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE - CLARIN ERIC - KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - CONSIGLIO NAZIONALE DELLE RICERCHE - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - KING'S COLLEGE LONDON - OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN - Istituto Centrale per il Catalogo Unico delle biblioteche italiane e per le informazioni bibliografiche - GEORG-AUGUST-UNIVERSITAT GOTTINGENSTIFTUNG OFFENTLICHEN RECHTS - SOCIETA INTERNAZIONALE PER LO STUDIO DEL MEDIOEVO LATINO-S.I.S.M.E.L.ASSOCIAZIONE - ACADEMY OF ATHENS - FACHHOCHSCHULE POTSDAM - DIGITAL RESEARCH INFRASTRUCTURE FOR THE ARTS AND HUMANITIES - - - EUR 11 999 711 - - - Pooling Activities, Resources and Tools for Heritage E-research Networking, Optimization and Synergies - - - EUR 11 999 711 - - - Italy - France - Netherlands - Netherlands - Ireland - Italy - France - Spain - Greece - United Kingdom - Austria - Italy - Germany - Italy - Greece - Germany - France - - - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - Higher or Secondary Education Establishments - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - PARTHENOS aims at strengthening the cohesion of research in the broad sector of Linguistic Studies, Humanities, Cultural Heritage, History, Archaeology and related fields through a thematic cluster of European Research - Infrastructures, integrating initiatives, e-infrastructures and other world-class infrastructures, and building bridges between different, although tightly, interrelated fields. PARTHENOS will achieve this objective through the definition and support - of common standards, the coordination of joint activities, the harmonization of policy definition and implementation, and the development of pooled services and of shared solutions to the same problems. - - 2019-04-30, ongoing project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-4-2014-2015 - Implementation and operation of cross-cutting services and solutions for clusters of ESFRI and other relevant research infrastructure initiatives - - - RIA - Research and Innovation action - - - Italy - - - PARTHENOS - - - H2020-INFRADEV-1-2014-1 - - - 654119 - - - - - UNIVERSITY OF BRISTOL - UNIVERSITY OF BRISTOL - ISTANBUL TEKNIK UNIVERSITESI - BATH SPA UNIVERSITY - - - EUR 2 000 000 - - - Beyond East and West: Developing and Documenting an Evolving Transcultural Musical Practice - - - EUR 2 000 000 - - - United Kingdom - United Kingdom - Turkey - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - For composers in Turkey today, the urge to integrate the beauties of Turkey’s rich musical heritage into contemporary concert music has become almost an imperative. But differences in tuning, texture, and between oral and - notated orientations to performance have presented seemingly intractable obstacles. This project systematises practical processes essential for the creation of a new, East-West strand of contemporary music and opera. It initiates cutting-edge - research workshops in Istanbul, Holland and the UK to: 1. Train top-level traditional instrumentalists and singers in Turkey effectively to perform a new repertoire; 2. Train top professional Western singers in non-Western techniques and nuances of - vocal production; 3. Develop approaches for modelling such music's impacts on Turkish and Western musicians’ adaptive processes in rehearsal and performance, and diverse audiences’ perceptions of such music; 4. Create an ensemble interface (including - newly designed instruments) to increase capacity for merging sounds beyond levels now achievable; 5. Produce groundbreaking studies on timbre to provide new insights into how sound is produced; 6. Establish a new template for mapping Eastern and - Western tuning systems onto one another. This research, together with an orchestration manual for Turkish sounds will comprise the core of a published (CUP) team-authored e-book, Integrating Turkish Instruments and Voices into Contemporary Music - (ITI), with included audio and visual examples linked as an online resource. Looking further, this project’s multi-modal, transdisciplinary approach also suggests a model for probing how the ‘free play’ of the imagination (Kant) possible within - processes of art and its creation can provide metaphors towards understanding one of the most urgent and compelling issues of our time: how to transcend cultural barriers (real or imagined) that exist today. - - 2020-08-31, ongoing project | - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - Integrating Turkish - - - ERC-2014-CoG - - - 648810 - - - - - KING'S COLLEGE LONDON - - - EUR 183 454,80 - - - Structural and functional studies of LARP4, a new RNA binding protein involved in mRNA stabilisation and cell migration - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - RNA-binding proteins (RBPs) act at multiple levels to regulate gene expression, including mRNA splicing, polyadenylation, localisation, stability, decay and translational efficiency and, although central to health and disease, - much of this precise concerted regulation remains to be uncovered. The recently discovered LARP4 is an RBP that affects mRNA stability and binds to polyA as well as the polyA-binding protein (PABP). Intriguingly, LARP4 has recently been identified as - a regulator of cell morphology and migration in an RNAi screen, but little is known about how control of gene expression at the translational level is coordinated during cell migration and invasion. Since aberrant cell migration contributes to the - development of human diseases including cancer, chronic inflammation and atherosclerosis, LARP4 represents an excellent RBP to advance our understanding of key cellular mechanisms relating to mRNA processing and turnover. - - - 2018-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - LARP4MOT - - - H2020-MSCA-IF-2014 - - - 655341 - - - - - UNIVERSITY OF PORTSMOUTH HIGHER EDUCATION CORPORATION - - - EUR 183 454,80 - - - Cosmology with voids and superclusters: combining theory, simulation and observation - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The aim of this cosmology proposal is to study the contents, history and evolution of our Universe, using the distribution of matter on large scales. I propose to study new methods to identify and catalogue rare voids and - superclusters in the large-scale structure of the Universe and to study their statistical, morphological and dynamical properties. I will use these studies to propose new observables and new techniques of data analysis based on these structures, and - to use this knowledge to test theories of gravitation, dark energy and the initial conditions of the early Universe. Interest in cosmic voids in particular has increased greatly in recent years, as they have been suggested as extremely competitive - probes of cosmology, according to some estimates significantly out-performing other methods. Yet there remain unsolved theoretical difficulties in the modelling of voids and even a lack of consensus on how to identify them and how to relate theory - and observation. Even less is currently known about superclusters. These are among the important issues I propose to address. My proposal consists in roughly equal parts of: analysis of the latest high-quality survey data which will available from - the Sloan Digital Sky Survey (SDSS) and the Dark Energy Survey (DES); analysis of the state-of-the-art Jubilee ISW and weak lensing simulations run on the Juropa supercomputer in Germany; and theoretical work to combine insights from data and - simulation to improve our understanding of cosmology. The proposed work is to be carried out in collaboration with leading experts in the respective fields from across the European Community, in particular in the United Kingdom, Spain and Germany. - - 2017-09-30, closed project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - COSMOVOID - - - H2020-MSCA-IF-2014 - - - 660053 - - - - - INSTITIUID TEICNEOLAIOCHTA BHAILE ATHA CLIATH - - - EUR 175 866 - - - Automated Raman spectral Cytology for detection of human papillomavirus (HPV) infection and cervical pre-cancer - - - EUR 175 866 - - - Ireland - - - Higher or Secondary Education Establishments - - The Experienced Researcher (ER), Dr Shiyamala Duraipandian, who is at the centre of this application, will, through this MSCA Fellowship, enhance her research and innovation potential through advanced training, international - and inter-sectoral mobility. The ER will develop methods for detecting high risk HPV infection and dysplasia using Raman spectroscopy in cervical cells collected during routine Pap smear screening. Her skills in instrument and software development - and patient testing will complement the expertise of the host laboratory. During the project measurable knowledge transfer towards the ER will be facilitated through DIT’s Postdoctoral Training Programme, RESC induction and specialist skills - transfer, strengthened academic and industry network contacts, via existing networks and industry events, and preparation of a dedicated career development plan. - - 2018-01-17, closed project - - - 2016-01-18 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Ireland - - - ARC-HPV - - - H2020-MSCA-IF-2014 - - - 661398 - - - - - UNIVERSITY OF BRISTOL - - - EUR 195 454,80 - - - Hierarchical surface patterns from dissolution-reaction-crystallisation mediated evaporation controlled self-assembly (DRC-ECA) and its antimicrobial coating application - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - A preliminary study by the applicant (Dr. Hua Wu (HW)) has proposed a novel dissolution-reaction-crystallisation mediated evaporation controlled self-assembly (DRC-ECSA) mechanism, from surprising and unprecedented - observations of complex residual surface patterns with hierarchical architecture self-assembled upon evaporative drying of a ZnO nanofluid droplet. This mechanism is very different from that previously established for the coffee ring effect and other - ECSA processes, and the morphological and nanostructural details of the obtained surface patterns also depend intricately on – thus are tuneable by – a range of physical parameters. Much of the complexity due to these corroborating factors remains to - be fully explored. The aim of the project is threefold: 1) to fully understand the DRC-ECSA mechanism by comprehensively investigating the effects of physical parameters such as the solvent mixtures, evaporation rate, ZnO nanofluid concentration, - shape and size of ZnO particles, addition of surfactants and polymers, substrate chemistry, droplet volume, temperature and humidity; 2) to apply and extend the DRC-ECSA mechanism (e.g. in a confined geometry and using binary particle mixtures) to - obtain sophisticated surface patterns with tailored morphologies and hierarchical structures; 3) to evaluate the efficacy of the surface patterns for potential applications in antimicrobial coatings. By leading and engaging in the proposed project, - Dr. HW will acquire new skills and knowledge in a range of interdisciplinary and multidisciplinary scientific and technical areas, including non-equilibrium ECSA, nucleation and crystal growth, morphological and structural characterization, - nanoparticle synthesis, and microbiology of nanostructured surfaces. A broad range of transferrable skills acquired through the enriching experience of this interdisciplinary project will be very beneficial to Dr. HW’s longer term career plans to - become an independent research leader. - - 2017-09-03, closed project - - - 2015-09-04 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - DRC-ECSA - - - H2020-MSCA-IF-2014 - - - 656830 - - - - - DEBRECENI EGYETEM - - - EUR 109 679,40 - - - Knowledge, Skills and Attitudinal Competences for Quality Early childhood Education and Care - - - EUR 109 679,40 - - - Hungary - - - Higher or Secondary Education Establishments - - The education and training of the Early Childhood Education and Care (ECEC) workforce is of prime importance as it equips practitioners with the knowledge, skills and attitudinal competences needed to work with children. - Training supports them in creating quality environments for children to enhance the quality of provision and subsequent child outcomes. The research is timely with the increased interest in the benefits of quality ECEC for supporting the holistic - development of children, but with a need to understand more about the role of the workforce in this. Whilst qualifications have been established as important for the quality of ECEC, little is known about the nature of the qualifications and the role - that they play in developing the knowledge, skills and attitudinal competences needed to best enhance the quality of ECEC provision. The research will focus on ECEC qualification requirements, structure, content and characteristics across Europe. The - project will analyse (via secondary data) the qualification requirements across Europe, the composition of the qualifications and their relationship to child outcomes. This macro level analysis will be supported by a detailed investigation (via - empirical research) into the delivery of qualifications and the role they play in developing the knowledge, skills and attitudinal competences appropriate to the context. The detailed investigation of qualifications will consider the formulation, - delivery, experiences and application of ECEC higher education training in the host’s institution, selected for its expertise in training kindergarten pedagogues in Hungary. ECEC in Hungary is under explored, whilst also offering an interesting case - to study due to how its history, market composition and quantity of provision contrast with those experienced by the Fellow in the UK. Pertinent for this research is emerging evidence on the divergent views of the knowledge, skills and attitudinal - competences needed to work in ECEC. - - 2017-02-28, closed project | - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Hungary - - - ECECWorkforce - - - H2020-MSCA-IF-2014 - - - 657512 - - - - - UNIVERSITY OF BRISTOL - - - EUR 195 454,80 - - - Hydrocarbon Oxidation Mechanisms Elucidated from Radical scavenging - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Oxidation reactions of hydrocarbons are of central importance to both atmospheric and combustion chemistry, where they play a pivotal role in determining the capacity of a hydrocarbon to persist in the air or burn as a fuel. - However, quantitative and complete measurements of the mechanisms by which oxidation occurs are very uncommon. Yet it is these mechanisms that ultimately determine the chemistry, influencing such diverse processes as tropospheric ozone production, - secondary organic aerosol formation, soot formation and autoignition of fuels. Conventional approaches typically involve mimicking atmospheric or combustion conditions within a chemical reactor. Common to both of these chemical regimes are the - phenomena of radical chain propagation, radical–radical reactions and multiple reaction pathways, leading to complex reaction mixtures that evolve rapidly with time. Subsequent gas samples are subjected to detailed and often ambiguous interpretation, - placing high demands on detailed chemical models in which only a small proportion of the reactions described within underwent direct experimental measurement. This fellowship seeks to challenge these existing approaches with an alternative - methodology in which the short-lived initial products of oxidation, the alkyl radicals, are rapidly converted into stable halogenated species before reaction mixtures become complex, providing crucial information on the fundamental reaction steps at - work in these systems. These mixtures will be analyzed by conventional, low cost gas-chromatography methodologies, where the inherent sensitivity and discriminating power of the electron-capture detector towards halocarbons will be exploited. By - combining this technique with recent insights into radical scavenging using molecular halogens, a unique and diverse apparatus emerges, which will be used to interrogate several classes of reaction. - - 2018-04-03, ongoing project - - - 2016-04-04 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - United Kingdom - - - HOMER - - - H2020-MSCA-IF-2015 - - - 702794 - - - - - UNIVERSITY OF BRISTOL - - - EUR 183 454,80 - - - LOCAL OWNERSHIP IN SECURITY SECTOR REFORM ACTIVITIES WITHIN CSDP OPERATIONS OF THE EU - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Between 2002 and 2014, the EU has deployed 30 civilian and military operations in Europe, Africa and Asia, under its Common Security and Defense Policy (CSDP). For most of these operations, the EU has a mandate to do - activities related to the Security Sector Reform (SSR), aimed at the provision of national and human security within a framework of democratic governance. One of the core assumptions underpinning the EU’s operations has been that SSR has to be - “locally owned” in order to be successful, meaning that local agents should internalize principles and objectives of externally driven reforms. Local ownership, however, remains a neglected concept not only theoretically speaking, but it is also very - difficult to be implemented in practice. The theoretical and policy gap informs three principal aims of this project. First, the project will adopt a fresh theoretical framework for the study of local ownership. Drawing on the work of Michel - Foucault, the project will conceptualize local ownership as a technology of international security “governmentality” wherein external actors employ set of techniques with the aim of turning local agents into subjects responsible for externally-driven - security sector reform agenda. Such an approach will situate local ownership of CSDP operations within a wider context of emerging liberal security governance and explain why it continuously face implementation difficulties in semi-liberal or - illiberal settings. Second, the project will obtain new empirical insights into how local ownership is being practised on the ground within three ongoing CSDP operations (EULEX Kosovo, EUPOL COPPS and EUTM Mali) and into why these projects continue - to face implementation problems. The third objective of the project is to develop a set of policy recommendations that will assist future policy planners in conceiving more reflexive, context-sensitive and cost-effective local ownership strategies to - be applied in current or future CSDP operations. - - 2017-10-06, closed project - - - 2015-10-07 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - EU and SSR - - - H2020-MSCA-IF-2014 - - - 656971 - - - - - UNIVERSITY OF BRISTOL - - - EUR 183 454,80 - - - Magnetic micromachines based on protocell design and engineering - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Protocells are artificial cellular systems exhibiting lifelike properties, which are proposed as a stepping-stone for understanding the origin of life on Earth. Features such as encapsulation, replication, metabolism and - selective exchange of chemicals with the environment will enable their use as micromachines in a number of emerging applications (e.g., environment clean-up, clinical diagnosis, drug delivery, remote sensing, bioreactor technology). However, progress - in such applications will be enhanced by the synthetic construction of protocells capable of directed movement in fluidic environments in response to external stimuli. To date, motility has been achieved only in a few cases, which involve a response - to changes in chemical concentrations (chemotaxis) in the surrounding medium. However, controlling the chemical composition of the local environment is challenging, and thus alternative ways to stimulate motility are needed. In this regard, external - magnetic fields (MFs) will enable high levels of control of protocell motility and spatial disposition to be achieved by employing noncontact forces. This is the aim of this proposal: to design and construct synthetic protocells able to sense and - respond to external MFs. A key outcome of the work will be the development of a new class of magnetic micromachines based on protocell design and engineering. Such machines will couple MF-directed motility with the temporal and spatial delivery of - advanced biomimetic functions. The key factor of the proposed methodology is the inclusion of colloidal magnetic particles at strategic locations in the protocell composition or in the external medium. Thereby, the expertise of the applicant (Dr. - Rodríguez Arco) in the field of MF-responsive materials will be applied to the multidisciplinary and cutting-edge field of protocells in which the hosting group at the University of Bristol (under the leadership of Prof. Mann FRS) has made great - progress in the last few years. - - 2017-04-30, closed project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - MagProtoCell - - - H2020-MSCA-IF-2014 - - - 656490 - - - - - UNIVERSITE PARIS 13 - - - EUR 185 076 - - - Homotopy theory of cosimplicial unstable (co-)algebras over the Steenrod algebra - - - EUR 185 076 - - - France - - - Higher or Secondary Education Establishments - - This research proposal is in mathematics, its content is part of algebraic topology and homotopy theory. It aims at deepening our understanding of the homotopy theory of cosimplicial unstable (co-)algebras over the Steenrod - algebra and its relation to the homotopy theory of cosimplicial spaces. This is achieved by new methods developed recently by the ER (Dr. Biedermann) and coauthors and by methods from Goodwillie calculus. Specifically, there are three closely related - parts/work packages: - - - 2017-04-30, closed project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - HotCoalgebras - - - H2020-MSCA-IF-2014 - - - 661067 - - - - - UNIVERSITA DEGLI STUDI DI TRENTO - - - EUR 180 277,20 - - - The neural basis of visual interaction between scenes and objects - - - EUR 180 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - We easily categorize places and objects in a single glance, a computationally complex task presenting a central challenge for vision neuroscience. Considerable evidence points to a division of scene and object processing into - two distinct neural pathways, relying on different types of visual cues. However, scenes and objects are also known to strongly interact in visual perception, as seen in contextual effects of background on object perception. At present, the neural - mechanisms by which scenes and objects interact remain unknown, leaving a critical gap in our understanding of these two major visual paths. The main goal of this multi-method proposal is to uncover the neural mechanisms of scene-object interactions. - I therefore propose three competing theoretical models. A parallel model predicts only stimulus-driven representations of scenes and objects in the visual cortex. In contrast, interactive models predict that representations of scenes and objects in - the visual cortex are influenced by one-another. However, whereas a visual-interactive model suggests direct interaction, a feedback model suggests that the interaction is mediated by frontal regions. To test this, I propose a novel psychophysical - paradigm of seeing objects from scene context and scenes from object context. Thereby, I will examine how scene and object processing are affected by one-another and identify the potential neural sources of these modulations using fMRI (objective 1). - Thereafter, I will use MEG to decode the timeline of these neural processes (objective 2). Establishing a clear neurocognitive model for scene-object interaction would not only advance our understanding of the two central paths of the ventral visual - stream, but also significantly contribute to the definition of vision as an interactive system rather than a set of specialized parallel modules. Shifting from localized visual modules to interactive visual processes will broaden my expertise as a - cognitive neuroscientist. - - 2018-05-31, ongoing project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - SEEING FROM CONTEXT - - - H2020-MSCA-IF-2014 - - - 659778 - - - - - UNIVERSITEIT VAN AMSTERDAM - - - EUR 165 598,80 - - - Rearm cultivated tomato with natural and durable resistance mechanisms from wild tomato species - - - EUR 165 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Insects are gaining resistance to commercially available pesticides and effective insecticides (e.g. neonicotinoids) are currently being banned. Consequently, there is a real threat that the EU vegetable production will be - affected. Wild tomato species have the ability to defend themselves by producing natural defence compounds that have a toxic or repellent effect on insects. These compounds are produced and stored in glandular hairs (trichomes) on the plant stem and - leaf surface. Extensive breeding in protected environments led to the loss of these defence compounds in cultivated tomatoes. It was previously shown that the introduction of the terpene 7-epizingiberene biosynthetic pathway from a wild tomato in - trichomes of cultivated tomato results in an enhanced resistance to insects. However, the regulatory factors that govern the production of these defence compounds seem also essential for successful incorporation of ‘wild resistance’ into breeding - material. Here, I aim to discover metabolic defence mechanisms present in the trichomes of wild tomato species that can be re-introduced into cultivated tomato with a focus on post-transcriptional regulation of biosynthetic pathways. I will evaluate - insect resistance in a collection of wild and cultivated tomato accessions and associate phenotypic and transcriptional data via a Systems Biology approach. I will also sequence small RNAs and compare them quantitatively with messenger RNAs to - identify post-transcriptional regulations. Next, I will follow a comparative genomic approach by mapping the selected transcripts to their corresponding tomato genomes to associate polymorphisms and resistance phenotypes. These results will be - directly translated into molecular markers that the industry can implement in breeding programmes. This proposal will help me become an independent researcher, combining my background in plant biology with knowledge on bioinformatics, biostatistics - and state-of-the-art technology. - - 2017-04-30, closed project | - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - DURETO - - - H2020-MSCA-IF-2014 - - - 655656 - - - - - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - - - EUR 173 076 - - - Role of Id4 in the adult subventricular zone of normal and injured brain - - - EUR 173 076 - - - France - - - Research Organisations - - The aim of this proposal is to propose a scientific research project and a training plan for Dr. Brenda Rocamonde. The scientific research project aims to understand the function of the transcriptional regulator Id4 in the - adult subventricular zone (SVZ) under physiological and pathological conditions. The SVZ is one of the largest neurogenic niches of the adult brain, generating new neurons from neural stem and progenitor cells, throughout adulthood. This region is - activated after brain injury, such as ischemic stroke. Inhibitor of DNA binding 4 (Id4) is a transcriptional regulator that acts by antagonizing transcription factors. In the developing brain, Id4 is required for neural progenitor cell proliferation - and differentiation. However, the function of Id4 in the adult SVZ has not been reported. We have observed that Id4 is expressed in neural stem cells and cells of the neuronal lineage in the adult SVZ. We propose to use in vivo approaches to (i) - determine Id4 function in the SVZ by loss and gain of function approaches, and (ii) evaluate its role in the response of the SVZ to ischemic stroke, a major cause of disability in Europe. This project, undertaken in an international research center - and carried out by a talented fellow will provide insights into the mechanisms underlying the regulation of adult neurogenesis in the normal and injured brain. In addition, we are proposing a career development plan for Dr. Rocamonde that includes - training on scientific and transferable skills. This plan will widen Dr. Rocamonde’s competences and provide her with the tools to become a leading independent researcher. - - 2017-07-31, closed project - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - ID4 - - - H2020-MSCA-IF-2014 - - - 661044 - - - - - KING'S COLLEGE LONDON - - - EUR 195 454,80 - - - Single Molecule Study of Protease Mechano-Specificity - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Single-molecule enzymology offers new possibilities to dissect catalytic reactions that were previously unapproachable using biochemistry techniques conducted in the bulk. In particular, recent discoveries conducted at the - single molecule level, such as the unanticipated force-mediated protein degradation pathway in the proteasome, highlight the close relation between mechanical forces and proteolysis in vivo. While much has been discovered about protein enzymology in - the recent decades, the question of how mechanical force affects enzymatic catalysis remains vastly elusive. The main goal of this proposal is to understand the mechanobiology of proteolysis at the single molecule level. We will use the newly - developed force-clamp spectroscopy technique, together with molecular biology engineering techniques and bioinformatics structural analysis to elucidate the molecular mechanisms that underlie protease catalysis under mechanical force. Successful - enzymatic activity relies on the enzyme:substrate (E:S) assembly. Upon mechanical unfolding, proteins unveil their buried substrate sites, also called cryptic sites, thus favoring the formation of the E:S complex and ultimately permitting the - subsequent chemical reaction. A key feature of recent mechano-chemistry experiments at the single bond level is that the rate at which the reduction of a protein disulfide bond occurs in the presence of a nucleophile is exponentially dependent on the - stretching force. Hence, it is tempting to speculate that, in the case of an enzymatic reaction, the catalytic rate will be also force-dependent. We anticipate that the curved geometry of the bound substrate inhibits the E:S assembly at high-forces, - implying a novel mechano-specificity character of proteases. Within a multidisciplinary approach, here we propose a series of innovative experiments to directly probe the effect of force on the kinetics of protease hydrolysis. - - 2017-03-31, closed project | - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - MECHANOPROTEASES - - - H2020-MSCA-IF-2014 - - - 656721 - - - - - UNIVERSITEIT VAN AMSTERDAM - - - EUR 177 598,80 - - - Identification and characterization of the sex pheromone sensitive response gene(s) in the European Corn Borer males - - - EUR 177 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Night-active Lepidoptera are among the most speciose group of animals (~120.000 known species) and they possess a unique sexual communication system: females attract conspecific males by using a species-specific sex pheromone - blend. Due to this fine-tuning, the development of novel pheromone systems is an evolutionary mystery: production of a new pheromone blend by females and preference for that blend by males must be established simultaneously, which is difficult to - explain when the female blend and the male response are controlled by independently assorting genes. The pheromone strains of the European Corn Borer, Ostrinia nubilalis provide one of the best model system for a better understanding of pheromone - (co)-evolution, because in these strains the females produce opposite proportions of E11- and Z11-tetradecenyl acetate, to which only strain-specific males are attracted. The genes responsible for the strain difference in female production are - autosomally encoded and identified as fatty-acyl reductase while the gene(s) underlying male response has(have) been found to be sex-linked but have not been identified yet. For years they have been hypothesized to be olfactory receptors (ORs). - However, we found with fine-scale mapping that the ORs map away from the Z-linked response locus and we showed two new candidate genes mapping at the male response region on the Z chromosome. The new candidates are involved in neurogenesis in other - species and therefore are interesting for all olfaction and neurogenesis studies, including studies on humans. With our multidisciplinary experience, combining genetic engineering, neurophysiology and behaviour, we wish to identify the genetic change - of the genes underlying male response in O. nubilalis and functionally characterize their involvement in olfaction. This approach has the potential to a) identify novel genetic mechanisms that underlie the evolution of pheromone communication and b) - develop new pest management strategies - - 2017-10-14, closed project - - - 2015-10-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - ECBStrainShift - - - H2020-MSCA-IF-2014 - - - 661322 - - - - - UNIVERSITY OF BRISTOL - - - EUR 183 454,80 - - - “EPIgenetic impacts on early-stage SPECiation and adaptive radiation” - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Phenotypic plasticity plays a key role at the onset of the speciation process, facilitating diversification though the induction of novel phenotypes in response to distinct environments. Via genetic accommodation and genetic - assimilation, this influence may extend throughout the speciation process and beyond, into subsequent speciation events. While the epigenetic regulation of gene expression that mediates phenotypic plasticity has been extensively studied in lab-based - model organisms, very little is known about epigenetic variation in natural populations. This project will be the first epigenetic study explicitly focused on the speciation process. Using cutting-edge techniques, the applicant will characterize DNA - methylation variation within and among the sympatric species of a recently discovered endemic cichlid fish radiation in Lake Massoko, Tanzania. Specifically the applicant will test: if 1) newly formed species differ in the distributions of epigenetic - marks across the genome, 2) genomic variants linked to phenotypic divergence among species are in genomic regions unusually high in DNA methylation, as expected under a hypothesis of epigenetic differences preceding fixed nucleotide differences - during adaptive divergence, 3) genomic regions diverging in patterns of methylation among incipient species are also exhibiting high levels of methylation in populations of Astatotilapia calliptera, the ancestral, colonizing species. The results of - this pioneering project will provide the first empirical evidence of the importance of epigenetic variation during the emergence of new species. - - 2017-03-31, closed project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - EpiSpec - - - H2020-MSCA-IF-2014 - - - 659791 - - - - - TECHNISCHE UNIVERSITAET WIEN - - - EUR 166 156,80 - - - Many-body effects in hybrid quantum systems - - - EUR 166 156,80 - - - Austria - - - Higher or Secondary Education Establishments - - The interdisciplinary field of hybrid quantum systems pursues the integration of different quantum systems from AMO and solid-state physics to harness their combined functionalities in an optimal way. Prominent examples are - long-lived spin ensemble quantum memories for superconducting qubits or (opto-)mechanical quantum transducers, which are currently experimentally implemented for future quantum information processing applications. - - 2017-03-31, closed project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Austria - - - MEHYB - - - H2020-MSCA-IF-2014 - - - 657788 - - - - - UNIVERSITEIT VAN AMSTERDAM - - - EUR 165 598,80 - - - Tensionless strings of six-dimensional superconformal theories - - - EUR 165 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Despite the important role they play in M-theory, six-dimensional superconformal field theories (SCFTs) are to this day not well understood. A characteristic feature of 6d SCFTs is that their degrees of freedom include - tensionless strings; while some properties of these strings have been studied in recent years, the 2d SCFTs that govern their behavior have not been constructed. In this proposal I outline a research plan to determine the 2d theories governing the - strings, and use this knowledge to study the dynamics of six-dimensional SCFTs. - - 2018-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - 6D STRINGS - - - H2020-MSCA-IF-2015 - - - 708045 - - - - - UNIVERSITEIT VAN AMSTERDAM - - - EUR 165 598,80 - - - The impact of Massive Binary Stars through Cosmic Times - - - EUR 165 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Massive stars, i.e. stars that are up to million times brighter than ordinary stars such as our Sun, play many important roles in astrophysics. They can be considered as (I) Cosmic Engines as they transformed the pristine and - dark Universe left after the Big Bang into the modern Universe in which we live today. We use them as (II) Cosmic Probes to study the most distant galaxies and we monitor their eruptions and explosions as (III) Cosmic Transients. As a result, various - fields in astrophysics heavily rely on the input of stellar models. Unfortunately, the widely used models are out-dated: they consider massive stars to be single. - - - 2017-03-31, closed project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Netherlands - - - BinCosmos - - - H2020-MSCA-IF-2014 - - - 661502 - - - - - UNIVERSITY OF BRISTOL - - - EUR 183 454,80 - - - Stereocontrolled synthesis of polypropionates based on building block assembly strategies by lithiation-borylation methodologies - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Amongst all natural products, polyketides constitute a very important class due to their broad spectrum of biological activities (eg. antibiotic, antitumoral, antifungal, antiparasitic). Many of these compounds are referred to - as polypropionates, which are characterized by sequences of methyl- and hydroxy-bearing stereogenic centres, enabling large numbers of possible stereochemical permutations. The importance of these natural products as therapeutic agents and as - biomedical tools together with their structural complexity has made these molecules attractive targets for synthetic organic chemistry. The key to construct these systems, which posses a high level of stereochemical information, is the control of the - absolute and relative stereochemistry of each centre. Herein we propose the development of a novel and general strategy for the synthesis of any polypropionate-like molecule based on the construction of a building block assembly platform. This - process will capitalize on the well-established lithiation-borylation methodology so complete control of both relative and absolute stereochemistry of all chiral centres will be achieved. The power of the strategy will be demonstrated in the - synthesis of the polypropionate core of the antibiotic Streptovaricin U. The successful development of this research will shortcut the synthesis of stereochemically defined polypropionates combining building blocks of varying length. Moreover, the - possibility to modify the stereochemistry of any centre will allow access to all known natural polypropionate fragments and will permit the preparation of non-natural analogues too. The development of such an ambitious and innovative project in the - University of Bristol will be facilitated by generating, transferring, sharing and disseminating knowledge, and will enhance my career development following the training plan envisioned. - - 2017-08-31, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - BBLOCK - - - H2020-MSCA-IF-2014 - - - 655682 - - - - - KING'S COLLEGE LONDON - - - EUR 183 454,80 - - - The role of innate lymphoid cells in regulating intestinal inflammation - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The maintenance of intestinal homeostasis has local and systemic implications for the host health and depends on a balance regulated by interactions between the immune system and the gut microbiota. Recently, it has become - clear that a newly identified group of cells, innate lymphoid cells (ILCs), have a crucial role in intestinal homeostasis and host defence. ILCs respond rapidly to changes in the gut microenvironment and produce several cytokines that regulate - intestinal inflammation. Although the pathways responsible for ILCs’ development and differentiation are only starting to be elucidated, the transcription factor T-bet has emerged as a key regulator of these processes. - - 2017-04-30, closed project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - Tbet ILC JFN - - - H2020-MSCA-IF-2014 - - - 659882 - - - - - UNIVERSITAET HAMBURG - - - EUR 159 460,80 - - - Interactions, Spins and Edges in Optical Lattices with Topological Band Structures - - - EUR 159 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - Electrons in a magnetic field experience a drift transverse to their velocity, which gives rise to intriguing effects such as the whole family of Hall Effects. Interestingly, this drift can also appear without a charged - particle and without magnetic field, i.e. for ultra-cold quantum gases in optical lattices with non-trivial topology, described by a Berry curvature. This enables researchers to use the tunability of quantum gases and allow for studies beyond the - possibilities of condensed matter systems. Furthermore, it allows to mimic and study in great detail fascinating effects such as topological insulators and edge-states. Especially, the interplay between topology and interactions is not well - understood and the existence of many interesting states, such as topological insulators, fractional Chern insulators and topological superfluids, is predicted, but have not yet been observed. In recent years, great progress has been made in - engineering topological band structures for quantum gases. Whereas theoretical proposals are well developed, so far there are only few experimental realizations of topological band structures, especially for fermionic quantum gases. In this action, - we want to create non-trivial topological band structures and explore (many-body) phases that can emerge for fermions and mixtures of bosons and fermions. We will map out the Berry curvature and study the detection of edge states, which provides a - clear signature of a non-trivial topology. For the first time, we will realize a new creation and detection method for topological band structures and study high spin Fermi systems in topological optical lattices. - - 2018-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - ISOTOP - - - H2020-MSCA-IF-2014 - - - 652837 - - - - - THE FRANCIS CRICK INSTITUTE LIMITED - Cancer Research UK - - - EUR 195 454,80 - - - Investigating eukaryotic replisome dynamics at the single molecule level - - - EUR 195 454,80 - - - United Kingdom - United Kingdom - - - Research Organisations - Research Organisations - - For cells to reproduce, an accurate duplicate of the genome must be created. This is no small task. The genetic information stored in each cell consists of ~6 billion pairs of nucleobases (base pairs, bp) assembled as a - polymer 2 metres long and 2 nanometres in diameter, with the structural form of a double helix. For a mammalian cell to divide, this deoxyribonucleic acid (DNA) must be copied in a time frame on the order of 1 day, or ~70,000bp a second. DNA - replication is common to all 3 domains of life, bacteria, archaea and eukarya and is accomplished by a complex of proteins. This proposal brings together a researcher of great proficiency in single molecule methods and multidisciplinary research with - the Single Molecule Imaging group at the London Research Institute, one of the world leading centres in DNA replication. Combined, we will build unique instruments and develop single molecule assays to understand the molecular gymnastics of DNA - replication in eukaryotes. We will elucidate rates of DNA unwinding by eukaryotic helicases and establish enhancements by association with other proteins. We will also study replisome dynamics by observing synthesis of DNA on custom templates in real - time. This will allow detection of replication loops and stalling that may occur. We will also examine the mechanism of lesion bypass. The insight gained is impossible with classical biochemical techniques, as individual replisomes are observed in - real time rather than measuring an average of a population. Our methods will reveal heterogeneities and obtain precise quantitative details of the dynamics. Features such as pauses and back slips will enable the study of intermediate states and - conformational changes linked to replisome dynamics. This proposal will satisfy academic curiosity of understanding life at the most fundamental level but will also increase our knowledge of the how the cell works and thus becomes the building blocks - for disease treatment and cures of the future. - - 2017-07-31, closed project - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SMI REP - - - H2020-MSCA-IF-2014 - - - 657479 - - - - - KING'S COLLEGE LONDON - - - EUR 183 454,80 - - - Characterization of islet-specific CD8 T cells in the honeymoon of type 1 diabetes - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Type 1 Diabetes (T1D) is a metabolic disease that results from the autoimmune attack against insulin-producing β-cells in the pancreatic islets of Langerhans. T1D usually comprises a phase called ‘honeymoon’, an interesting - though poorly studied period of the disease where exogenous insulin requirements are decreased, postulating a possible attempt of β-cell regeneration and a remission of the autoimmunity. The proposed research aims to identify and characterize - islet-specific CD8 T cells, the final effectors of β-cell death, in the honeymoon of T1D. We plan to perform a cross-sectional and longitudinal study with T1D patients where the immunological and metabolic characterization will be collected during - the first year of the disease, and analysed by flow cytometry, enzyme immunoassays, gene expression and functional assays. - - - 2018-09-14, ongoing project - - - 2016-09-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - HONEYDIAB-8 - - - H2020-MSCA-IF-2015 - - - 704974 - - - - - NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU - - - EUR 196 400,40 - - - Software-defined Intermittent Networking - - - EUR 196 400,40 - - - Norway - - - Higher or Secondary Education Establishments - - In the ever-growing Internet of Things (IoT), Wireless Sensor Networks (WSNs) play an increasingly important role, with a strong demand for robust solutions in extreme environments. The aim of this proposal is to develop a - networking solution that handles the intermittent communication links that characterise such environments. - - 2018-05-01, ongoing project - - - 2016-05-02 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Norway - - - SINet - - - H2020-MSCA-IF-2015 - - - 699924 - - - - - UNIVERSITY OF BRISTOL - - - EUR 183 454,80 - - - Dangerous Masculinities: Young Men in Italian Cinema of the 1940s-1960s - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The present project aims to examine Italian cinema during the twenty-year period from 1943 to 1963 in relation to the construction of the image of the young Italian man. The main goals are to understand how Italian cinema from - the post-war period to the ‘economic boom’ gave substance to male national identities and to situate those identities within an emerging youth culture produced by the new consumer society in Italy. - - 2018-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - Young-Italian 2015 - - - H2020-MSCA-IF-2015 - - - 704227 - - - - - UNIVERSITY OF BRISTOL - - - EUR 183 454,80 - - - A multi-method perspective on children's use of rehearsal in serial recall tasks - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Rehearsal is a key construct in models of immediate memory and refers to the overt or covert repetition of items to counteract forgetting. A long-standing assumption is that children younger than 7 years do not engage in - rehearsal, as such children tend not to show key ‘experimental effects’ thought to be signatures of rehearsal. However, given a growing debate in the adult experimental literature on the interpretation of these effects, and more recent concerns in - the developmental literature about how one should understand changes in their magnitude, the questions of when rehearsal develops, and the role that it plays in supporting serial recall in children become open once again. - - 2018-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - MMPCURSRT - - - H2020-MSCA-IF-2015 - - - 707141 - - - - - UNIVERSITY OF BRISTOL - - - EUR 195 454,80 - - - Assessing the aerosol radiative impact employing advanced methods to reduce uncertainties in the aerosol optical properties - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Understanding how anthropogenic aerosols impact the Earth’s climate system is a daunting challenge. Aerosol radiative effects are strongly dependent on the optical and microphysical properties of the particles. Uncertainties - in the absorption coefficient and the single scattering albedo (SSA) contribute significantly to the overall uncertainties in the optical properties of aerosol and their radiative effect. Not only does hydration cause an increase in size, but it also - alters the complex refractive index (RI) of the particle; the real part of the RI governs the scattering of light by the aerosol and the imaginary part the degree of absorption. Thus, quantifying the relationships of chemical composition, relative - humidity (RH) and particle phase with complex RI is critical for predicting the aerosol radiative forcing. Since these optical properties determine the magnitude and even the sign of the effect of aerosol on the Earth’s energy balance, it is vital - that we understand their range. Although techniques have been developed to measure the scattering and absorption cross-sections of ambient and laboratory particles, interpreting measurements can be challenging. Using a new technique to accurately - determine the extinction cross-sections of single particles developed in the Bristol laboratory, we will provide a rigorous assessment of treatments used to characterise the optical properties of aerosol. Of particular emphasis, we will examine the - optical properties of mixed-component aerosol and the influence of chemical aging of organic aerosol on light absorption. Crucially, the parameterisations for optical properties that result will then be used to refine (and assess sensitivities of - direct forcing to) the treatment of aerosol properties in radiative transfer and global climate models. This work will also provide crucial information to improve our understanding of field and remote sensing instruments. - - 2018-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - REDRAF - - - H2020-MSCA-IF-2015 - - - 700843 - - - - - JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN - - - EUR 159 460,80 - - - Accounting for genocide: legal and scientific accounting practices in the wake of the Srebrenica genocide - - - EUR 159 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - “Accounting for genocide” empirically considers two sociomaterial practices of accounting for the 1995 Srebrenica genocide in Bosnia and Herzegovina. First, it scrutinizes efforts of national and international organizations to - (ac)count how many Bosniak men were massacred and who was killed in July 1995. The second question about accounting analyses how those politically responsible at the time of the genocide are legally tried at the International Criminal Tribunal for - the former Yugoslavia (ICTY). The first practice of accounting is based on inter alia forensic science, statistics, missing persons lists and witnesses conveniently subsumed under ‘atrocity victim identification’ (AVI), the second practice is the - domain of adversarial legal proceedings, developing international criminal law, transitional justice and controversies over the Srebrenica genocide and legitimacy of the ICTY. A rigorous qualitative analysis focusing on the various - locations—mass-graves, family assistance centres, forensic laboratories, the ICTY, public domain—where objects like remains, missing persons, identities, crimes, DNA evidence, and legal cases come to matter provides a deep understanding of the - question of how both practices of accounting become entangled and co-construct each other. - - 2017-12-31, closed project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - Genocide accounting - - - H2020-MSCA-IF-2014 - - - 660707 - - - - - LINKOPINGS UNIVERSITET - - - EUR 173 857,20 - - - Transistor sensors for in-vivo sucrose monitoring in plants - - - EUR 173 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - In order to address the challenge of undernourishment we need to understand better how plants grow, how they interact with their environment, and how to increase plants’ productivity. During the past decades important progress - has been made in plant biology due to the development of genetic and genomic tools. Still many questions remain unanswered highlighting the need for the development of complementary technologies to genetic methods. Plants’ growth and productivity are - determined by photosynthesis and the way its products, such as sucrose, are distributed and utilized during the growth and development of the plant. The goal of Trans-Plant is the development of a complementary technology based on organic - bioelectronics that will allow in-vivo sucrose monitoring in the vascular tissue of the plant from source to sink and give new insight to the transport mechanism of sucrose. This project will focus on interfacing organic bioelectronics with plants - and developing the devices in-vivo where the plant’s complex structure consists of an integral part of the device. It will open up new possibilities for monitoring and controlling physiology in plants and result in the development of a state of the - art device concept and technique for organic bioelectronics and plant science. During the fellowship Eleni Stavrinidou will be trained to develop a unique set of expertise, she will gain new knowledge and skills in more than one discipline, she will - acquire transferable skills and she will expand her scientific and industrial network through collaborations and meetings. Therefore this fellowship will accelerate her scientific and professional development. - - 2018-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - Trans-Plant - - - H2020-MSCA-IF-2015 - - - 702641 - - - - - JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN - - - EUR 171 460,80 - - - Building a computational basis for the brain response in the left ventral occipito-temporal cortex: Understanding the Sparse Familiarity Model of visual word recognition - - - EUR 171 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - The left ventral occipito-temporal cortex (lvOT) is an integral part of the ventral visual processing stream and is consistently activated in response to visual words. Recently, I developed a computational implementation of - the lvOT functioning during visual word recognition, the sparse familiarity model (SFM). The single assumption of the SFM is that the statistical patterns of letter string familiarity are the fundament of lvOT functioning. The SFM is able to simulate - prominent lvOT benchmark contrasts and its simulations predict brain activation of the lvOT in multiple fMRI studies. The main aim of the present proposal is to use the model to systematically investigate hotly debated topics in word recognition - research concerning current theoretical approaches for the lvOT: (1) The influence of learning and (2) domain specificity (i.e. for words) vs. generalization (i.e., to face and object recognition) of lvOT function and neuronal populations. In the - course of these investigations, the SFM will be developed into a learning model and a generalized model for word, face, and object recognition. Central to this will be high-density electrophysiological measurements (MEG) that sample brain activation - with high temporal resolution and reasonable spatial resolution, to allow connectivity analysis at different time points. The MEG measurement, in addition to fMRI measures, will be essential to test theoretical assumptions concerning the proposed two - stages of the SFM that differ fundamentally in terms of neuronal and cognitive mechanisms. Critical will be the association of these stages to different time windows and assumptions about the brain networks involved. The host, Prof. Fiebach at - Frankfurt University, has a strong focus on the neurocognitive basis of language and access to an MEG, which is essential for realizing this project. To summarize, the goal of the project is to establish the sparse familiarity model and extend its - functioning to resolve current debates. - - 2018-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - SFM4VOT - - - H2020-MSCA-IF-2015 - - - 707932 - - - - - UNIVERSITY OF BRISTOL - - - EUR 195 454,80 - - - Electrophile-Mediated Three-Component Enantiospecific Cross-Couplings - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - One of the most challenging aspects of Suzuki-Miyaura reactions is the stereospecific cross-coupling of sp3 substituted boronic esters with aryl halides. Recently, the host group developed a metal-free, stereospecific - cross-coupling reaction of chiral alkyl boronates with electron-rich aromatics, promoted by the use of electrophilic oxidants. This proposal seeks to substantially extend this cross-coupling chemistry through the application of a range of different - electrophiles that will not only mediate the cross-coupling process, but also remain in the final product, creating multiple carbon–carbon bonds stereospecifically. In particular, the application of electrophilic organometallic species will be - investigated so as to take advantage of the power of metal catalysts in the formation of carbon–carbon bonds. Through the use of this strategy, doubly functionalised enantiopure aromatic compounds may be formed in a very efficient three-component - coupling process that utilises readily accessible enantiopure alkyl boronic esters, electron-rich aromatics and catalytically generated organometallic electrophiles. - - 2017-02-28, closed project | - - - 2015-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - EMTECS - - - H2020-MSCA-IF-2014 - - - 652890 - - - - - UNIVERSITY OF BRISTOL - - - EUR 183 454,80 - - - NonAdiabatic Molecular Dynamics of organic Intermediates in Atmospheric chemistry - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Earth’s atmosphere is a massive photochemical reactor, and human activities are changing its chemical composition, impacting both climate and air quality. Detailed chemical mechanisms – constructed from coupled kinetic - networks of thousands of elementary reactions – are crucial in advancing our fundamental understanding of atmospheric chemistry, and developing reliable predictive models. Because the elementary mechanistic details of volatile organic compound (VOC) - oxidation are often beyond the reach of experiment, in silico molecular kinetics studies (utilizing ab initio quantum chemistry and nonequilibrium statistical mechanics) are increasingly used to construct atmospheric chemistry models – particularly - for describing VOC kinetics on electronic ground states. - - 2018-05-01, ongoing project - - - 2016-05-02 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - NAMDIA - - - H2020-MSCA-IF-2015 - - - 701355 - - - - - UNIVERSITE MONTPELLIER III PAUL VALERY - - - EUR 185 076 - - - The Court of Elizabeth I – A European Drama - - - EUR 185 076 - - - France - - - Higher or Secondary Education Establishments - - The enduring fascination in anglophone research with the political culture of Elizabethan England has often served to occlude the fact that responses to the Tudor monarch were formulated across renaissance Europe. A - pan-European range of dramatic texts bears witness to the anxiety and consuming interest which surrounded Elizabeth I. Such texts have often been neglected or referenced briefly as points of illustration. Moreover, these texts (where afforded any - consideration) have most commonly been seen in terms of national traditions of literary production, rather than integrated into a Europe-wide vision of cultural debate and exchange. None of these texts has been considered in recent centuries for - their theatrical potential or placed in close conversation with Elizabethan (or post-Elizabethan) literary production. - - - 2018-10-02, ongoing project - - - 2016-10-03 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - COEED - - - H2020-MSCA-IF-2015 - - - 702104 - - - - - JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN - - - EUR 159 460,80 - - - The environmental fate and effects of microplastics in freshwater ecosystems - - - EUR 159 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - EU member states are currently working towards the realisation of environmental goals specified in the Water Framework Directive (WFD), which aims to protect both human and ecosystem health. Microplastic particles (MPs) are - emerging pollutants of increasing concern and are formed primarily when plastic waste degrades in the environment. The impacts of MPs on freshwater biota are not known, however, they may present a potentially persistent and ecotoxicological pollution - problem. Accordingly, the goal of this project is to assess the environmental risk of MPs in freshwater habitats. To achieve this, a detailed investigation of MP environmental persistence will be carried out. This will provide environmental fate - summaries for different polymer classes and enable the modelling of their degradation processes. This will be combined with laboratory studies to assess relevant sub-lethal endpoints such as reproduction, fitness, inflammation, and oxidative stress. - As MPs are known to accumulate co-occurring organic pollutants, the toxicity of virgin MPs will be compared to MPs conditioned with relevant freshwater pollutants. This work will build towards a sophisticated state-of-the-art mesocosm study that will - evaluate both MP fate and impacts in model ecosystems. The establishment of a novel framework for the environmental risk assessment of MPs will inform our ability to achieve conservation objectives taking into account MPs as emerging pollutants. The - merit of this is that protection goals may be better accommodated in policy and management through the generation of so far unavailable data on MP persistence and environmental toxicity. Taken together, the project will generate so far unavailable - data sets to assess for the first time the environmental impacts of freshwater MPs. Thus, the outcomes will highly relevant for academia, politics, stakeholders and society. - - 2017-03-31, closed project | - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - FreshwaterMPs - - - H2020-MSCA-IF-2014 - - - 660306 - - - - - KING'S COLLEGE LONDON - - - EUR 183 454,80 - - - Genetic analysis of rare and common variation in a large Brazilian bipolar family - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - This proposal describes my aim to use a uniquely large multigenerational family to better understand the genetic underpinnings of mood disorders: the Brazilian Bipolar Family (BBF). The family has a high incidence of mood - disorders, featuring diminishing age of onset over generations and assortative mating, whereby many of the marriages in the family are between individuals with a psychiatric disorder. Mood disorders are leading contributors to the global burden of - disease. Bipolar disorder is characterized by periods of elevated mood and periods of depression. Major depressive disorder is characterized by pervasive and persistent low mood, low self-esteem and loss of interest or pleasure in normally enjoyable - activities. Heritability estimates are 37% for MDD and up to 75% for BP. The current picture for complex disorders is of a genetic architecture consisting of both common and rare variants contributing risk. Genetic studies of mood disorders have not - yet individual variants/genes accounting for a large increase in risk. The effect of common variants in the family context is unclear. I propose to utilize the BBF as a unique resource for studying both common and rare variation in mood disorders. - Its size offers a powerful means for mapping genetic loci for mood disorders that are individually rare but common within the family. It also provides us with a unique model in which to analyse individual genetic risk profiles, utilizing the large - sample size of and predictive ability of previous case-control association studies for each family member into a polygenic risk score. This will also allow me to assess assortative mating, which may act to increase polygenic risk to mood disorders - over generations. I will develop an approach which will allow me to incorporate genome-wide case-control study results into family studies – something with broad utility for the field. My study will shed light on the genetic pathology of mood - disorders, aiding prevention and treatment. - - 2017-04-30, closed project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - BBFGEN - - - H2020-MSCA-IF-2014 - - - 658195 - - - - - UNIVERSITA DEGLI STUDI DI TRENTO - UNIVERSITA DEGLI STUDI DI TRENTO - - - EUR 1 499 678 - - - The Home-Migration Nexus: Home as a Window on Migrant Belonging, Integration and Circulation - - - EUR 1 499 678 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The experience of home lies at the core of everyday life, but only through migration is it revealed as a complex and elusive social construction, whose micro analysis illuminates macro social issues and problems. How home - works in the life trajectories of those who left it behind, and what the search for home says of immigrant integration and of the influence of mobility on domesticity, are the central questions of HOMInG. By deconstructing the tension between the - static face of home and the dynamic face of migrant lives, this programme marks a turning point in the study of the social and emotional appropriation of space. It builds on a mixed-method research design on home as experienced by labour and forced - migrants, under different household arrangements, compared across several countries and groups of reference. - - - 2021-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Italy - - - HOMInG - - - ERC-2015-STG - - - 678456 - - - - - JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN - - - EUR 159 460,80 - - - Improved Fluid Dynamics for Relativistic Heavy Ion Collisions - - - EUR 159 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - One of the fundamental questions in the field of high-energy physics is what are the properties of strongly interacting matter at high temperature or density, when one expects a transition from hadronic degrees of freedom to - deconfined matter, quark-gluon plasma (QGP), where the degrees of freedom are quarks and gluons. - - - 2017-12-31, closed project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - IMFDforHIC - - - H2020-MSCA-IF-2014 - - - 655285 - - - - - KING'S COLLEGE LONDON - - - EUR 183 454,80 - - - Multi-modal interrogation of instinctive behaviours and intrahypothalamic connectivity - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Mammalian behaviour is driven by instincts such as hunger, sex and aggression which are familiar to everyone from daily experience. Anomalies in these instincts cause disorders such as anorexia, excessive sexual drive and - episodic dyscontrol syndrome, and potentially also psychologically difficult situations like marital infidelity. Neuronal circuits that drive these instincts reside in the hypothalamus where research is gaining pace rapidly. - - 2018-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - United Kingdom - - - DRIVOME - - - H2020-MSCA-IF-2015 - - - 701986 - - - - - UNIVERSITY OF DUNDEE - - - EUR 183 454,80 - - - Unravelling PIM kinase signal integration in the T cell response - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Understanding how T cells integrate alternative signal combinations to determine immune response strength and functionality is of critical importance for rational design of immunomodulatory therapies. The PIM kinase family - have been identified as important regulators of cell division, survival and protein synthesis independent of, but in parallel to the key signalling molecule mTOR. I propose to use cutting-edge quantitative proteomic technology to identify substrates - and downstream protein networks regulated by PIM kinase in activated T cells. I will investigate where these downstream targets qualitatively diverge from, or quantitatively interact with, the mTOR signalling pathway (Objective 1 and 2). Using - advanced cell culture and mathematical modelling I will quantify how this co-ordinated activity regulates T cell division, survival and differentiation outcomes (Objective 3). This comprehensive exploration of PIM kinase and mTOR signalling pathway - integration will provide important fundamental insight into how these signals combine to regulate T cell fate and may be manipulated in the context of immunotherapy or cancer. - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - PIM PROTEOMICS - - - H2020-MSCA-IF-2015 - - - 705984 - - - - - UNIVERSITY OF BRISTOL - UNIVERSITY OF BRISTOL - - - EUR 1 998 546 - - - Bird Inspired Autonomous Flight - - - EUR 1 998 546 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The agile and efficient flight of birds shows what flight performance is physically possible, and in theory could be achieved by unmanned air vehicles (UAVs) of the same size. The overall aim of this project is to enhance the - performance of small scale UAVs by developing novel technologies inspired by understanding how birds are adapted to interact with airflows. Small UAVs have the potential to dramatically change current practices in many areas such as, search and - rescue, surveillance, and environmental monitoring. Currently the utility of these systems is limited by their operational endurance and their inability to operate in strong turbulent winds, especially those that often occur in urban environments. - Birds are adapted to be able to fly in these conditions and actually use them to their advantage to minimise their energy output. - - 2021-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - BIAF - - - ERC-2015-STG - - - 679355 - - - - - UNIVERSITEIT VAN AMSTERDAM - - - EUR 165 598,80 - - - Wnt Enhancer LandscapE CharacTerization - - - EUR 165 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Despite significant efforts, cancer remains one of the major health challenges in Europe. - - 2018-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - WntELECT - - - H2020-MSCA-IF-2015 - - - 706443 - - - - - KING'S COLLEGE LONDON - - - EUR 183 454,80 - - - The Making of Modernist Resistance, 1880-1950 - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The vibrant diversity of an increasingly global modernity owes much to the cross-cultural exchanges between British and Indian modernists during their collaborations in civil rights, anti-colonial, and anti-fascist activism - from the 1880s to the 1950s. The proposed project examines the shifting nature of literary and political contributions to activist movements made by four such networks of British and Indian modernists to illuminate their integral role in creating - what I contend is a distinctively modernist resistance. As early as the 1880s, theosophists from Britain partnered with renowned Indian spiritualists to bridge cultural gaps between colonizer and colonized through shared mystical experiences to - emphasize an innate unity among human beings. By 1919, however, the disillusionment following World War I coupled with India’s outrage about the Amritsar Massacre in which General Dyer and his troops opened fire killing hundreds of innocent Indians, - supplanted such yearnings for unity with efforts to protect democratic freedoms from threats by right-wing extremists through a secular socialist resistance. Mulk Raj Anand, initially drawn to the liberal humanism of the Bloomsbury Group eventually - joined the radical socialists of India’s Progressive Writers Association in 1936. Women like Sarojini Naidu and Virginia Woolf fought for women’s equality and opportunities to join in anti-right-wing resistance. Mahatma Gandhi and Jawaharlal Nehru, - influenced by the socialist ideologies of the Fabian Society, incorporated them into Indian nationalism and governance. This study explores the relationship between the ideologies of these networks to establish what the shift from spiritualism to - secular socialist nationalism reveals about the nature of modernist resistance and the conditions of modernity that inspired it. The world view underpinning this resistance was integral in defining the post-war identities of Britain and India as - secular socialist-leaning democracies. - - 2017-08-31, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ssmscaifa - - - H2020-MSCA-IF-2014 - - - 659376 - - - - - UNIVERSITEIT MAASTRICHT - UNIVERSITEIT VAN AMSTERDAM - UNIVERSITY OF GLASGOW - THE BOARD OF TRUSTEES OF THE TATE GALLERY - UNIVERSIDADE NOVA DE LISBOA - TECHNISCHE HOCHSCHULE KOLN - UNIVERSITA DEGLI STUDI ROMA TRE - AKADEMIA SZTUK PIEKNYCH W WARSZAWIE - UNIVERSIDADE DO PORTO - COMUNE DI MILANO - - - EUR 3 812 140,80 - - - New Approaches in the Conservation of Contemporary Art - - - EUR 3 812 140,80 - - - Netherlands - Netherlands - United Kingdom - United Kingdom - Portugal - Germany - Italy - Poland - Portugal - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - The importance of European cultural heritage has been generally acknowledged. A significant part of this heritage, however, modern and contemporary art, runs a great risk of getting lost for future generations, because it is - particularly difficult to preserve. Proper care requires resolving fundamental questions concerning the identity and authenticity of modern and contemporary artworks and the consequences for their conservation, rethinking historically grown - professional distinctions as those between the curator and the conservator, re-organizing the institutional ecosystem, and establishing frameworks for international, interdisciplinary and intersectoral research and training collaboration. The aim of - this Marie Curie Innovative Training Network is to educate a new generation of professional curators, conservators and academic researchers who are properly equipped to face these challenges. The key notion guiding the research and training - programmes will be the notion of reflective practice. Starting from the theoretical framework of practice theory, the research programme will investigate conservation practices through the comparative analysis of their impact on modern and - contemporary artworks’ biographies. The training programme will focus on the development of a reflective professional attitude, which is a pre-requisite in this increasingly complex and collaborative field. - - 2019-05-31, ongoing project | - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Netherlands - - - NACCA - - - H2020-MSCA-ITN-2014 - - - 642892 - - - - - UNIVERSITEIT VAN AMSTERDAM - UNIVERSITEIT VAN AMSTERDAM - - - EUR 1 500 000 - - - Precision Multi-Scale Predictions for the LHC: Higgs, Jets and Supersymmetry - - - EUR 1 500 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - My project will boost the precision of theoretical predictions for collisions at the Large Hadron Collider. Precise predictions are crucial to further constrain the properties of the recently-discovered Higgs boson, and - uncover a faint signal of Beyond-the-Standard Model physics. I will focus on the strong interactions, which dominate the theoretical uncertainty and play a role at multiple energy scales, including those related to the incoming protons, the hard - scattering, the masses of (new) particles, the transverse momentum and size of jets. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - MULTISCALE - - - ERC-2015-STG - - - 677323 - - - - - KING'S COLLEGE LONDON - - - EUR 195 454,80 - - - Regulation of lipid-mediated immunity in the intestine - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The gastrointestinal tract is continuously exposed to multiple antigens from commensal bacteria, food and pathogens. The mechanisms by which the gut mucosa tolerates trillions of commensal bacteria without developing - inflammation remains poorly understood. It is increasingly appreciated that commensal bacteria-derived products regulate the homeostasis and/or function of many immune cell populations. Commensal bacteria-derived lipids are recognized by a population - of unconventional T cells, called NKT cells. NKT cells specifically recognize through their T cell receptor lipid antigens presented by the MHC-I-like molecule CD1 which is expressed by a variety of immune cells within the intestinal tissue. - Importantly, commensal-derived lipids modulate the numbers, phenotype and function of intestinal NKT cells. Conversely, dysregulation of NKT cell activation and/or CD1 expression have been associated with the development of colitis in mice and - humans. Despite the abundance and diversity of microbial-derived lipids present in the gut, the molecular and cellular mechanisms that mediate their recognition by immune cells and the identity of the antigen presenting cells involved in this process - remain unknown. By using a combination of multiparametric flow cytometry, genetic engineering and in vivo experiments this proposal aims to unravel the mechanisms and functional consequences of lipid-presentation in the mucosa. These studies will - provide a better understanding of the factors that modulate intestinal immunity, with the potential to improve therapies for patients suffering from intestinal inflammatory diseases and possibly a broader range of disorders. - - 2018-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - LIPID IMMUNITY - - - H2020-MSCA-IF-2015 - - - 703639 - - - - - TECHNISCHE UNIVERSITAET WIEN - - - EUR 166 156,80 - - - Entangled Twin Atom Beams - - - EUR 166 156,80 - - - Austria - - - Higher or Secondary Education Establishments - - Many of the fascinating phenomena predicted by quantum mechanics, like non-local correlations and entanglement, were implemented with photons in the framework of quantum optics. It is today a mature field with applications - emerging in cryptography, random number generation, and quantum computation. Based on the analogy between matter waves and electromagnetic waves and on particle-wave duality, quantum atom optics started to develop recently, thanks to the development - of tools for matter wave manipulation. A crucial point for the success of quantum optics was the availability of twin-photon sources, based on a non-linear medium. Very recently, several approaches towards realizing twin-atom pairs have been - investigated (most notably by the applicant and the host institution of this proposal) and successfully realized. The ETAB project will use this new twin atom beam (TAB) source to implement quantum atom optics experiments. Characterization of the - resulting strongly correlated states will be performed through measurement of correlation functions. These experiments will go beyond the analogy with quantum optics due to fundamental differences between atoms and photons: mass and intrinsic - nonlinearity due to interactions. This second property allows high efficiency twin atom beam generation, with an important pump depletion. This allows us to investigate new physics, including beyond linear response, quantum simulation, and - non-equilibrium physics. Furthermore, by preparing the twin beams in an entangled state, we will perform the first test of Bell inequalities with untrapped atoms, which could rule out spontaneous decoherence or gravitational nonlinearity models. - - 2017-03-31, closed project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Austria - - - ETAB - - - H2020-MSCA-IF-2014 - - - 656530 - - - - - KING'S COLLEGE LONDON - KING'S COLLEGE LONDON - - - EUR 1 759 064 - - - Quantum Black Holes: A macroscopic window into the microstructure of gravity - - - EUR 1 759 064 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The thermodynamic behavior of black holes is a precious clue in unravelling the microscopic structure of quantum gravity. High precision computations of quantum black hole entropy provide a new window into the fundamental - microscopic theory of gravity and its deviations from classical general relativity. Traditional methods of quantum field theory have proved to be not well-suited to perform these computations. Two breakthroughs in my recent work establish new ground - for progress. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - QBH - - - ERC-2015-CoG - - - 681908 - - - - - UNIVERSITE DE CAEN NORMANDIE - UNIVERSITE DE CAEN NORMANDIE - - - EUR 1 153 750 - - - Theory of Stein Spaces in Berkovich Geometry - - - EUR 1 153 750 - - - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Complex Stein spaces may be thought of as analytic analogues of the affine schemes of algebraic geometry. They may be characterized in several manners: using convergence of holomorphic functions, topological properties or - potential-theoretic properties, for instance. Especially useful for applications is the fact that their coherent cohomology vanishes. Despite the crucial importance of this theory in complex analytic geometry, its p-adic counterpart has hardly been - sketched. - - 2020-06-30, ongoing project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - TOSSIBERG - - - ERC-2014-STG - - - 637027 - - - - - UNIVERSITEIT VAN AMSTERDAM - UNIVERSITEIT VAN AMSTERDAM - - - EUR 2 000 000 - - - Exploring the Plurality of New Worlds: Their Origins, Climate and Habitability - - - EUR 2 000 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Recent surveys have revealed an amazing, and yet unexplained, diversity of planets orbiting other stars. The key to understanding and exploiting this diversity is to study their atmospheres. This is because exoplanets’ - atmospheres are unique laboratories that hold the potential to transform our understanding of planet formation, physics, and habitability. This is a new opportunity to place the Solar System and the Earth’s ecosystem in a broader context; one of the - main goals of modern astrophysics. - - - 2021-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - EXO-ATMOS - - - ERC-2015-STG - - - 679633 - - - - - UNIVERSITAET BERN - UNIVERSITAET BERN - THE UNIVERSITY OF READING - MODUL UNIVERSITY VIENNA GMBH - - - EUR 1 952 183 - - - Indigenous Communities, Land Use and Tropical Deforestation - - - EUR 1 952 183 - - - Switzerland - Switzerland - United Kingdom - Austria - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Tropical deforestation is an important contributor to climate change, through the release of significant amounts of carbon in the atmosphere. The main proximate cause of deforestation in tropical regions is agricultural - expansion, followed by timber extraction. The general objective of this research is to understand how the interaction of technological, environmental, economic and social factors influence land use dynamics, including household decisions, about - agricultural expansion and resource extraction in sensitive tropical regions. More specific questions relate to the role of various governance structures, particularly those recognizing common property regimes of land tenure to indigenous and rural - communities, and the deliberative evaluation about the opportunity of reforming such structures in order to reduce deforestation and forest degradation. Although such aspects have been addressed in a variety of contexts, the approach proposed here is - novel as a) it explicitly models the interaction between institutional, environmental, technological and socio-economic factors at different spatio-temporal scales, b) it specifically focuses on the governance structures associated with different - land tenure regimes through the lenses of Social Network Analysis (SNA), c) uses a Q-methodology framework to develop a participatory approach to study stakeholders’ perspectives and attitudes on the necessary governance interventions to prevent - deforestation and forest degradation and d) it assesses the relationships between agricultural expansion, deforestation, governance structures and stakeholders’ attitudes, with particular attention to the sensitivity of household land use decisions - and resource extraction. In order to meet the research objectives, this project will focus on the province of Salta in the dry Chaco in North-Western Argentina, a region characterized by high rates of land cover change and the presence of - indigenous/rural communities. - - 2021-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Switzerland - - - INCLUDE - - - ERC-2015-CoG - - - 681518 - - - - - KING'S COLLEGE LONDON - - - EUR 183 454,80 - - - Cortical circuit assembly in the developing mouse neocortex - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The developing neocortex consists of two major neuronal subtypes–pyramidal neurons and interneurons. These two subtypes come together in the cortical plate, forming cortical circuits that can integrate and respond to external - and internal stimuli. Despite recent advancement in the research on cortical networks of the developing brain, the mechanism involved in cortical circuit assembly remains relatively unexplored. This project aims to identify the sequence of events and - factors involved in cortical circuit assembly in the developing mouse brain. As such, this project can be broadly divided into three main parts namely lamination, synaptogenesis and maturation of the MGE interneurons specifically. Currently, the - exact mechanisms that govern MGE interneurons are still unknown except that it may involve cues that are produced by the pyramidal neurons. Therefore, we aim to use existing transcriptome data of the different neuronal layers coupled with the - acquisition of the early- and late- born MGE interneurons transcriptome in order to identify the receptor-ligand pair that is involved in the specific lamination of MGE interneuron. We also aim to understand the sequence of events that occur during - synaptogenesis and maturation of MGE interneurons. To achieve this, we will be performing live imaging on organotypic brain slices of sparsely labeled MGE interneurons and by selectively killing specific classes of interneurons in order to determine - the effect of these cells on the maturation of the parvalbumin-expressing interneuron. Altogether, this proposed project will give a better insights into the factors and mechanisms underlying cortical circuit assembly in the developing brain and will - pave the way for a better understanding into the aetiology of certain neurodevelopmental disorders. - - 2019-08-14, ongoing project - - - 2017-08-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - CorCir - - - H2020-MSCA-IF-2015 - - - 705311 - - - - - UNIVERSITEIT VAN AMSTERDAM - UNIVERSITEIT VAN AMSTERDAM - - - EUR 1 748 656,25 - - - Migration as Development - - - EUR 1 748 656,25 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - How do processes of development and social transformation shape human migration? More specifically, how do development process affect the geographical orientation, timing, composition and volume of both internal and - international migration? The relation between development and human mobility is highly contested. While economic development in poor countries and areas is usually seen as the most effective way to reduce migration, other studies suggest that - development actually increases migration. However, evidence has remained highly inconclusive so far because of theoretical and methodological limitations. - - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - MADE - - - ERC-2014-CoG - - - 648496 - - - - - KING'S COLLEGE LONDON - - - EUR 195 454,80 - - - Towards a typology of Visigothic script: the Beatus British Library Add. 11695 and its potential for dating and localising Visigothic script manuscripts - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The main aim of the proposal is to establish a point of reference for the analysis of Visigothic script, the primary carrier of Latin writing in the Iberian Peninsula from the 8th to the 14th centuries. To date, most - palaeographical analysis of Visigothic script has been conducted using a traditional methodology and following heterogeneous criteria, which has led to subjective results difficult to share or evaluate. In contrast, my research will create a - computerised database of quantitative data by applying a specially designed method, a starting point that will allow codices written in Visigothic script to be described, compared and placed in their socio-cultural context. Innovative techniques for - digital analysis of manuscript sources that will be acquired in the host institution will allow me to gain new insights into the analysis of the script while opening new avenues of research by applying digital tools to its study. The knowledge thus - generated will be of great practical importance for future palaeographical and textual research establishing criteria upon which advanced studies can build. It will offer a means of understanding the script, its manuscripts, and its cultural context. - - - 2017-08-31, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ViGOTHIC - - - H2020-MSCA-IF-2014 - - - 656298 - - - - - KING'S COLLEGE LONDON - KING'S COLLEGE LONDON - - - EUR 1 993 802,59 - - - Dissecting the cellular mechanics of contact inhibition of locomotion - - - EUR 1 993 802,59 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Our aim is to dissect the mechanisms of contact inhibition of locomotion (CIL), a process whereby migrating cells collide and repel each other, as it is now clear that CIL is pivotal to understanding embryogenesis and - pathologies such as cancer. We have developed an in vivo model using Drosophila macrophages (hemocytes), along with novel analytical tools, to examine the contact inhibition response in cells during development. We therefore have an unprecedented - opportunity to address CIL in a genetically tractable organism within a physiologically relevant setting. This model has revealed that a precisely controlled CIL response is a significant driving force behind the acquisition of embryonic patterns, - and recent data show that this precision requires a series of synchronized changes in cytoskeletal dynamics. Our central hypothesis is that key to this cellular ‘dance’ is mechanosensation of the collision, which integrates subsequent signaling - mechanisms to choreograph the steps of the contact inhibition process. The first part of this proposal will elucidate the molecular mechanisms controlling CIL by exploiting our unique ability to live image and genetically dissect this process in - Drosophila. We will also take an interdisciplinary approach to elucidate the mechanical aspects of the response, which will allow us to examine the feedback between signaling pathways and the physical forces of the CIL response. We will subsequently - extend our detailed understanding of the CIL process, and our novel set of analytical tools, to mammalian cell types and model systems. This will allow us to develop new assays to directly probe the mechanics of CIL and begin to investigate the - function of this underexplored process in other cell types. This in depth knowledge of the response places us in the best position to extend our understanding of CIL to new physiologically relevant scenarios that in the future will impact on human - health. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - CIL2015 - - - ERC-2015-CoG - - - 681808 - - - - - UNIVERSITEIT VAN AMSTERDAM - UNIVERSITEIT VAN AMSTERDAM - THE UNIVERSITY OF MANCHESTER - - - EUR 1 497 270 - - - The design and development of efficient biocatalytic cascades and biosynthetic pathways for the sustainable production of amines - - - EUR 1 497 270 - - - Netherlands - Netherlands - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The objective of this project is to design and develop biocatalytic cascades, using purified enzymes in vitro, as well as biosynthetic pathways in whole cell microbial organisms. These biocatalytic cascades and biosynthetic - pathways will be developed for the synthesis of chiral and achiral amines that are of particular interest for the chemical industry. The amine functionality will be introduced using amine dehydrogenases (AmDHs) as biocatalysts in the pivotal core - enzymatic step. AmDHs are a new class of enzymes that have recently been obtained by protein engineering of wild-type amino acid dehydrogenases. However, only two AmDHs have been generated so far and, moreover, they show a limited substrate scope. - Therefore protein engineering will be undertaken in order to expand the substrate scope of the already existing AmDHs. In addition, novel AmDHs will be generated starting from different wild-type amino acid dehydrogenases as scaffolds, whose amino - acid and DNA sequences are available in databases, literature, libraries, etc. In particular, protein engineering will be focused on the specific chemical targets that are the objectives of the designed biocatalytic cascades and in addition, - screening for more diverse substrates will also be carried out. Finally, the AmDHs will be used in combination with other enzymes such as alcohol dehydrogenases, oxidases, alkane monooxygenases, etc., to deliver variously functionalised amines and - derivatives as final products with elevated yields, perfect chemo- regio- and stereoselectivity, enhanced atom efficiency and minimum environmental impact. Such an approach will be realised through the design of new pathways that will convert - inexpensive starting materials from renewable resources, encompassing the internal recycling of redox equivalents, the use of inorganic ammonia as nitrogen source and, if necessary, only molecular oxygen as the innocuous additional oxidant. Water - will be the sole by-product. - - 2020-04-30, ongoing project | - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - BIOSUSAMIN - - - ERC-2014-STG - - - 638271 - - - - - UNIVERSITEIT VAN AMSTERDAM - UNIVERSITEIT VAN AMSTERDAM - - - EUR 1 999 012 - - - Children and social robots: An integrative framework - - - EUR 1 999 012 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Robots used to be made for labor; now, they are increasingly also made for relationships. Social robots can learn from us, teach us, play with us, and assist us. With the market for social robots expected to grow substantially - in the next 20 years, social robots are likely to become a life-changing technology similar to personal computers or smart phones. Still, we still know little about one of the most intriguing, relevant, and timely issues in this process – children’s - interaction with social robots. Children are not only increasingly recognized and targeted as early adopters of new technologies; they may also be more susceptible to potential effects of interacting with robots than are adults. - - 2021-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - CHILDROBOT - - - ERC-2015-CoG - - - 682733 - - - - - UNIVERSITY OF BRISTOL - - - EUR 195 454,80 - - - Molecular palaeobiology and comparative genomics of chelicerate terrestrialisation - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Animals have marine origins, with only three phyla including lineages that can complete every phase of their life cycle outside of water–saturated environments. These phyla are the Vertebrata (reptiles, birds and mammals), the - Mollusca (land snails and the slugs) and the Arthropoda (e.g. insects, spiders, centipedes). The process through which animals adapted to life on land is referred to as terrestrialisation and it is one of the most fascinating unresolved problems in - evolutionary biology. The crossing of the water–land barrier was the most extreme case of adaptation to a new environment in animal history. In fact, the difference between the sea and the subaereal environment is so extreme that astrobiology uses - terrestrialisation as an analog to study how life could adapt to a new planet. - - - 2017-08-31, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - CheliceLand - - - H2020-MSCA-IF-2014 - - - 655814 - - - - - THE UNIVERSITY OF EDINBURGH - THE UNIVERSITY OF EDINBURGH - UNIVERSITEIT VAN AMSTERDAM - - - EUR 1 457 185 - - - Induction of Broad-Coverage Semantic Parsers - - - EUR 1 457 185 - - - United Kingdom - United Kingdom - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In the last one or two decades, language technology has achieved a number of important successes, for example, producing functional machine translation systems and beating humans in quiz games. The key bottleneck which - prevents further progress in these and many other natural language processing (NLP) applications (e.g., text summarization, information retrieval, opinion mining, dialog and tutoring systems) is the lack of accurate methods for producing meaning - representations of texts. Accurately predicting such meaning representations on an open domain with an automatic parser is a challenging and unsolved problem, primarily because of language variability and ambiguity. The reason for the unsatisfactory - performance is reliance on supervised learning (learning from annotated resources), with the amounts of annotation required for accurate open-domain parsing exceeding what is practically feasible. Moreover, representations defined in these resources - typically do not provide abstractions suitable for reasoning. - - 2021-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - BroadSem - - - ERC-2015-STG - - - 678254 - - - - - UNIVERSITY OF BRISTOL - UNIVERSITY OF BRISTOL - - - EUR 1 986 356 - - - Bio-Inspired Tools for Glycoscience - - - EUR 1 986 356 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Cell surface carbohydrates play key roles in cell recognition mechanisms. O-glycosylation is a ubiquitous post-translational modification that is highly dynamic and responsive to cellular stimuli through the action of cycling - enzymes. Expression of specific O-glycans is linked to changes in gene expression in, for example, inflammatory bowel disease, cystic fibrosis and several types of cancer. - - - 2020-06-30, ongoing project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - GLYCO-TOOLS - - - ERC-2014-CoG - - - 648239 - - - - - UNIVERSITEIT VAN AMSTERDAM - UNIVERSITEIT VAN AMSTERDAM - - - EUR 1 499 909 - - - Accurate simulations of strongly correlated systems with tensor network methods - - - EUR 1 499 909 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project aims to achieve ground-breaking advances in the biggest challenge in computational condensed matter physics: the accurate simulation of strongly correlated systems (SCS), which give rise to fascinating phenomena - such as high-Tc superconductivity (HTSC), quantum spin liquids with topological order, and other exotic phases of matter. While for one-dimensional (1D) systems tremendous progress has been made thanks to the famous density-matrix renormalization - group (DMRG) method, in higher dimensions accurate methods have been lacking for many years. Recently, I achieved several major breakthroughs with tensor network methods, which can be seen as an extension of DMRG to higher dimensions. I was able to - show that these methods outperform previous state-of-the-art approaches for several challenging models, making it clear that these methods will play a pivotal role in understanding SCS in 2D, in the same way as DMRG has revolutionized the study of 1D - systems. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - TENSORNETSIM - - - ERC-2015-STG - - - 677061 - - - - - UNIVERSITEIT VAN AMSTERDAM - UNIVERSITEIT VAN AMSTERDAM - - - EUR 1 499 938 - - - The mind's eye: How expectation and attention shape perception - - - EUR 1 499 938 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Perception is more than meet’s the eye; how we see the world is critically shaped by attention (what is relevant) and as a growing body of work indicates, by past experience (what is likely). Overturning the classical notion - of perception as a largely bottom-up process, the idea that our brain is a prediction machine, continually trying to predict what is ‘out there’ based on past experience, is quickly growing in stature and influence. Yet, little is still known about - how predictions shape perceptual experience. Moreover, it is completely unknown to what extent predictive processing occurs automatically. Lastly, how the brain ultimately ‘decides’ on one hypothesis or interpretation of the current sensory state is - still unclear. The proposed research program will address these outstanding questions with the ultimate aim to better understand how the brain infers the world and the mechanisms that give rise to perceptual experience. It will do so through an - integrated application of psychophysical, neuroimaging, brain stimulation, mathematical modelling, and pharmacological techniques. The research program comprises three projects. The first project will examine how expectations are implemented in the - brain and shape stimulus processing, independently from and aided by attention. The second project will reveal if one can teach oneself to be free of expectation and associated habitual responding, through intensive mental training, as cultivated by - meditation. The third project will test the idea that the striatum, a subcortical brain region, and its irrigation by the neurotransmitter dopamine play a critical role in updating our internal model about the environment and thereby conscious - perception. The proposed research will be critical in elucidating the mechanisms that underlie experience and the extent to which these mechanisms are plastic, and will have important implications for the study of clinical disorders characterized by - dysfunctional experience of the world. - - 2021-07-31, ongoing project - - - 2016-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - PERCEPT - - - ERC-2015-STG - - - 679399 - - - - - UNIVERSITY OF BRISTOL - UNIVERSITY OF BRISTOL - - - EUR 1 978 060 - - - Quantum Photonic Engineering - - - EUR 1 978 060 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - By harnessing the unique properties of quantum mechanics (superposition and entanglement) to encode, transmit and process information, quantum information science offers significant opportunities to revolutionise information - and communication technologies. - - - 2020-04-30, ongoing project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - QPE - - - ERC-2014-STG - - - 640079 - - - - - UNIVERSITY OF BRISTOL - UNIVERSITY OF BRISTOL - - - EUR 1 999 885 - - - Isotope CYcling in the LABrador Sea - - - EUR 1 999 885 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The high-latitude regions are experiencing some of the most rapid changes observed in recent decades: polar temperatures are rising twice as fast as the global mean and there are concerns about the impact of sea-ice and - glacier retreat on global oceans and climate. The high-latitude North Atlantic is also a key region for ecologically and economically important natural resources such as fisheries. How these resources will change in the future depends strongly on the - response of marine biogeochemical cycling of essential nutrients to increasing anthropogenic stress. - - 2021-06-30, ongoing project - - - 2016-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - ICY-LAB - - - ERC-2015-STG - - - 678371 - - - - - UNIVERSITEIT VAN AMSTERDAM - UNIVERSITEIT VAN AMSTERDAM - - - EUR 1 996 362,50 - - - The Logic of Conceivability: Modelling Rational Imagination with Non-Normal Modal Logics - - - EUR 1 996 362,50 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - “The human imagination remains one of the last uncharted territories of the mind” - - - 2021-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - LoC - - - ERC-2015-CoG - - - 681404 - - - - - UNIVERSITEIT VAN AMSTERDAM - UNIVERSITEIT VAN AMSTERDAM - - - EUR 1 405 652 - - - Causal Analysis of Feedback Systems - - - EUR 1 405 652 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Many questions in science, policy making and everyday life are of a causal nature: how would changing A influence B? Causal inference, a branch of statistics and machine learning, studies how cause-effect relationships can be - discovered from data and how these can be used for making predictions in situations where a system has been perturbed by an external intervention. The ability to reliably make such causal predictions is of great value for practical applications in a - variety of disciplines. Over the last two decades, remarkable progress has been made in the field. However, even though state-of-the-art causal inference algorithms work well on simulated data when all their assumptions are met, there is still a - considerable gap between theory and practice. The goal of CAFES is to bridge that gap by developing theory and algorithms that will enable large-scale applications of causal inference in various challenging domains in science, industry and decision - making. - - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - CAFES - - - ERC-2014-STG - - - 639466 - - - - - UNIVERSITEIT VAN AMSTERDAM - UNIVERSITEIT VAN AMSTERDAM - - - EUR 1 500 000 - - - At the roots of corruption: a behavioral ethics approach - - - EUR 1 500 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - For many years, human cooperation has been praised as beneficial in organizational and personal settings. Indeed, cooperation allows people to develop trust, build meaningful relationships, achieve mutually beneficial - outcomes, and strengthen bonding with one's group members. However, while the benefits of cooperation are clear, very little is known about its possible negative aspects. Such negative aspects include the potential emergence of unethical conduct - among cooperating partners, or as termed here – corrupt collaboration. Such joint unethical efforts, benefiting (directly or indirectly) one or more of the involved parties, occur in business, sports, and even academia. Corrupt collaboration emerges - when one party bends ethical rules (here: lie) to set the stage for another party to further bend ethical rules and get the job done, that is, secure personal profit based on joint unethical acts. We propose that corrupt collaborations most commonly - occur when all involved parties gain from the corrupt behavior. The current proposal is aimed at unfolding the roots and nature of corrupt collaborations; their existence, the psychological and biological processes underlying them, and the settings - most likely to make corrupt collaboration emerge and spread. Accordingly, the information gathered in the current proposal has the potential to change the commonly held conceptions regarding the unidimensional – positive – nature of cooperation. It - will help create a comprehensive understanding of cooperation and, specifically, when it should be encouraged or, alternatively, monitored. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - Corruption Roots - - - ERC-2014-STG - - - 637915 - - - - - KING'S COLLEGE LONDON - KING'S COLLEGE LONDON - - - EUR 2 499 817 - - - Mitochondrial DNA degradation and sterile inflammation in the heart - - - EUR 2 499 817 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Heart failure is the leading cause of morbidity and mortality in developed countries including EU. Novel and efficient therapeutics to treat patient with heart failure have to be developed. Mitochondria are subcellular - organelles that produce energy and dynamic organelles that fuse and divide. Dysregulated mitochondrial activity results in generation of free radicals which cause damage to cellular components. We reported that mitochondrial quality control by - autophagy is essential for normal cardiac functions (Nat Med 2007). Mitochondrial DNA (mtDNA) contains bacteria-like unmethylated CpG motifs, which are inflammatogenic. We reported that mtDNA that escapes from autophagy-mediated degradation leads to - inflammatory responses in cardiomyocytes and heart failure (Nature 2012). Damaged mitochondria in failing hearts are selectively removed by mitochondria-selective autophagy, mitophagy. Mitophagy is preceded by mitochondrial fission, which divides - elongated mitochondria into pieces for autophagy. Although Atg32 is essential for mitophagy in yeast, no homologue has been known in mammals. Recently, we identified Bcl2-like protein 13 (Bcl2-L-13) as a functional mammalian homologue of Atg32 which - induces mitochondrial fragmentation and mitophagy (Nat Commun in press) in mammalian cells. While methylation of nuclear DNA involves in epigenetic regulation of protein synthesis, the significance of mtDNA methylation in transcription and - autophagy-medicated inflammation remains to be elucidated. Our pilot study showed an isoform of DNA methyltransferase targets to mitochondria for mtDNA methylation. In this proposal, we shall attempt to characterize regulation mechanism of Bcl2-L-13 - and its in vivo function and to elucidate the physiological significance of mtDNA methylation. Furthermore, we shall elucidate the role of mtDNA methylation and Bcl2-L-13 in the genesis of heart failure and examine whether these will be the - therapeutic targets for the treatment of heart failure. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - RAMBO - - - ERC-2015-AdG - - - 692659 - - - - - JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN - JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN - - - EUR 2 458 468 - - - Cell-cell interactions at the neurovascular interface - - - EUR 2 458 468 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The coordinated orchestration of cell movements is a vital process for assembling functional structures. In recent years we have learned a simplifying lesson: organ development is governed by a limited set of conserved - cell-to-cell communication signaling pathways repeatedly used in different contexts. Particularly fascinating is the parallelism between the vascular and nervous systems. My lab has been working for more than a decade on the molecular and functional - parallelism between nervous and vascular system development and plasticity. Although it is clear that cellular communication between the different cells in the brain is fundamental for brain function, very little is known about the signaling - effectors that are used for such trans-cellular signaling. Molecular pathways involved in the crosstalk between vessels and neuronal cells are slowly emerging. How this crosstalk signaling is integrated at the interface of the different cellular - players (neurons, endothelial cells, glial cells) for proper brain development and function is still poorly understood. Here I propose to delineate the molecular pathways that govern such communication in order to understand basic mechanisms of brain - development, function and dysfunction. Using a combination of state-of-the-art inducible and cell type-specific genetics, both in mouse and zebrafish, together with high-resolution light microscopy and multi-photon live imaging we will examine the - cell-context dependent integration of signaling pathways in building up proper neuronal/glial structures and functional networks. We will use advanced ultra-structural analysis using serial block-face electron microscopy (SBEM) to obtain - high-resolution maps of cortical structures. Functionally, we will characterize the integration of vascular/glial/neuronal signals during cortical neuronal migration, arborization, synaptic connectivity, higher-order integrative cortical function and - behavior-related plasticity in vivo. - - 2020-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - NEUROVESSEL - - - ERC-2014-ADG - - - 669742 - - - - - UNIVERSITY OF BRISTOL - UNIVERSITY OF BRISTOL - - - EUR 1 873 483 - - - Exponential sums, translation invariance, and applications - - - EUR 1 873 483 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Title: Exponential Sums, Translation Invariance, and Applications. - - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - ESTIA - - - ERC-2015-AdG - - - 695223 - - - - - UNIVERSITEIT VAN AMSTERDAM - UNIVERSITEIT VAN AMSTERDAM - - - EUR 1 999 858 - - - Finance/Security practice after 9/11: Following the Money from Transaction to Trial - - - EUR 1 999 858 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The aim of FOLLOW is to understand and analyse the security practices that render financial transactions into security intelligence, into court evidence. The novel approach is to map the path of the suspicious financial - transaction as a ‘chain of translation.’ I ask what gets lost and added in the process of translating financial records from banks to courts. I deliver fine-grained empirical analysis of four key elements – privacy challenges, knowledge practices, - situated judgement, and effects – at each link in the chain: banks, Financial Intelligence Units (FIUs) and courts. I focus on four European Union member states that are most different cases: UK, Netherlands, Spain and Poland. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - FOLLOW - - - ERC-2015-CoG - - - 682317 - - - - - UNIVERSITEIT VAN AMSTERDAM - UNIVERSITEIT VAN AMSTERDAM - - - EUR 1 499 999 - - - The physics and forensics of neutron star explosions - - - EUR 1 499 999 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Neutron stars offer a unique environment in which to develop and test theories of the strong force. Densities in neutron star cores can reach up to ten times the density of a normal atomic nucleus, and the stabilizing effect - of gravitational confinement permits long-timescale weak interactions. This generates matter that is neutron-rich, and opens up the possibility of stable states of strange matter, something that can only exist in neutron stars. Strong force physics - is encoded in the Equation of State (EOS), the pressure-density relation. This is linked to macroscopic observables such as mass M and radius R via the stellar structure equations. By measuring and inverting the M-R relation we can recover the EOS - and diagnose the underlying dense matter physics. - - 2020-05-31, ongoing project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - CSINEUTRONSTAR - - - ERC-2014-STG - - - 639217 - - - - - KING'S COLLEGE LONDON - KING'S COLLEGE LONDON - THE UNIVERSITY OF NOTTINGHAM - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - UNIVERSITY OF SOUTHAMPTON - - - EUR 3 394 214,88 - - - Brain network based stratification of mental illness - - - EUR 3 394 214,88 - - - United Kingdom - United Kingdom - United Kingdom - Ireland - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - To reduce the burden of mental disorders it is a formidable aim to identify widely applicable disease markers based on neural processes, which predict psychopathology and allow for targeted interventions. We will generate a - neurobehavioural framework for stratification of psychopathology by characterising links between network properties of brain function and structure and reinforcement–related behaviours, which are fundamental components of some of the most prevalent - mental disorders, major depression, alcohol use disorder and ADHD. We will assess if network configurations define subtypes within and if they correspond to comorbidity across these diagnoses. We will identify discriminative data modalities and - characterize predictors of future psychopathology. - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - STRATIFY - - - ERC-2015-AdG - - - 695313 - - - - - JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN - JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN - - - EUR 2 497 398 - - - Endothelial long non-coding RNAs - - - EUR 2 497 398 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Endothelial cells comprise the inner cellular cover of the vasculature, which delivers metabolites and oxygen to the tissue. Dysfunction of endothelial cells as it occurs during aging or metabolic syndromes can result in - atherosclerosis, which can lead to myocardial infarction or stroke, whereas pathological angiogenesis contributes to tumor growth and diabetic retinopathy. Thus, endothelial cells play central roles in pathophysiological processes of many diseases - including cardiovascular diseases and cancer. Many studies explored the regulation of endothelial cell functions by growth factors, but the impact of epigenetic mechanisms and particularly the role of novel non-coding RNAs is largely unknown. More - than 70 % of the human genome encodes for non-coding RNAs (ncRNAs) and increasing evidence suggests that a significant portion of these ncRNAs are functionally active as RNA molecules. Angiolnc aims to explore the function of long ncRNAs (lncRNAs) - and particular circular RNAs (circRNAs) in the endothelium. LncRNAs comprise a heterogenic class of RNAs with a length of > 200 nucleotides and circRNAs are generated by back splicing. - - 2020-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - Angiolnc - - - ERC-2014-ADG - - - 667255 - - - - - UNIVERSITEIT VAN AMSTERDAM - UNIVERSITEIT VAN AMSTERDAM - - - EUR 1 918 306 - - - Groups and Violence: A Micro-sociological Research Programme - - - EUR 1 918 306 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The Group Violence research programme aims to understand how group behaviour affects the likelihood and severity of violence in public space. While the prevailing social scientific focus remains on individual perpetrators and - background factors, the empirical reality of public violence is one of multiple attackers, multiple victims and multiple bystanders. The research proposed here furthers the study of violence with a novel theory that identifies how group behaviour - affects the outcome of antagonistic situations – and with comparative empirical studies to test the theory. The central question is how and to what extent 1) mutual alignment of attention and action, and 2) a sense of moral community enable group - members to commit violence. Project 1 (PI and post-doc) considers mutual alignment down to the minutest detail, based on close-up qualitative and quantitative video analyses of sequences of bodily cues. Based on judicial case files, project 2 (PI and - assistants) will quantitatively analyse mutual alignment in an extensive range of violent interactions. Four PhD projects compare the role of mutual alignment and moral community in antagonistic situations in groups that differ from each other in - these respects: police teams (project 3), street youth (4), football hooligans (5), and bouncers (6). Relying on an innovative method to reconstruct antagonistic situations by repeated and comparative qualitative interviewing, projects 3-6 will also - relate the meanings of violence and masculine identity to the moral community of the group. Project 7 (PI and post-doc) uses qualitative and statistical analyses of the interview data generated in projects 3-6 for an extensive comparison of group - behaviour in antagonistic situations. The ambition is to produce exemplary understanding of the crucial role that groups play in violence. This proposal shows how: through detailed and extensive comparative empirical testing that will further develop - the new theory. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - GROUPVIOLENCE - - - ERC-2015-CoG - - - 683133 - - - - - UNIVERSITY OF PORTSMOUTH HIGHER EDUCATION CORPORATION - - - EUR 250 104,60 - - - Students, social change and the construction of the post-independence Algerian state, 1962-1978 - - - EUR 250 104,60 - - - United Kingdom - - - Higher or Secondary Education Establishments - - This project seeks to bring a new perspective to understanding state construction in Algeria after independence. Through a history of the first generations of Algerians who went to university in the 1960s and 1970s, it - explores the intersections between political and institutional transformations and social, cultural and economic processes. These processes include increasing literacy, rural to urban migration, migration to study abroad and changes in gender - relations and family structures. Bringing together concepts and methodologies from across a number of humanities and social science disciplines, the project will produce a case study setting out new approaches to studying state-building as a dynamic - process which takes place at different levels of power (transnational, national and local) and which both shapes, and is shaped by, individual agency and wider processes. The goal is for this approach to be applicable to a range of other - post-colonial contexts, challenging teleological readings of post-independence histories and homogenising understandings of post-independence states. - - - 2019-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - STUSOCSTA - - - H2020-MSCA-IF-2015 - - - 705763 - - - - - UNIVERSITY OF BRISTOL - - - EUR 258 107,40 - - - Elaboration and degeneration of complex traits: The visual systems of lizards and snakes - - - EUR 258 107,40 - - - United Kingdom - - - Higher or Secondary Education Establishments - - In “On the origin of species” Charles Darwin used the human eye as an example of a complex character the evolution of which would have been hard to explain. Since then the vertebrate eye and the origin of vision more broadly - held a central role in evolutionary biology. Recent advances in genomics, developmental biology and physiology, have allowed some advancement in our understanding of the origin of animal vision that however, is still patchy at best. Surprisingly, - modern integrative studies have largely overlooked the visual systems of the Squamata (i.e. the lizards and snakes), a group comprising ~25% of terrestrial vertebrates, displaying exceptional diversity, and with greater variation in eye morphology - and retinal photoreceptors than all other vertebrates combined. I propose to use the powerful but overlooked squamate system to answer major questions in visual science. I will integrate genomic, physiological and anatomical data to understand the - genomic underpinning of phenotypic variation in the vertebrate visual system the relative roles of adaptation and constraints in the origin of novel visual phenotypes, and to understand whether complex visual systems can be re-elaborated following - evolutionary degeneration. - - - 2019-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - Evol-Eyes - - - H2020-MSCA-IF-2015 - - - 703438 - - - - - UNIVERSITY OF BRISTOL - UNIVERSITY OF BRISTOL - - - EUR 1 467 038 - - - Comparative Analysis of Social Spaces in Post-Industrial Nations - - - EUR 1 467 038 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The proposed research has two overarching objectives. First, it aims to examine whether it is possible and appropriate to extend a novel way of measuring social class recently devised for the United Kingdom to other - post-industrial nations for the purposes of cross-national comparative research. If it is, the project will begin to explore, through secondary and primary analysis of large-scale survey data, the different shapes and trajectories of the class - structures – or ‘social spaces’ – of various nation states. This will involve examination of which classes and sub-classes predominate and which have emerged or declined, as well as the different gender and ethnic/nationality constitutions of the - classes and the distinct effects these differences have for understanding cultural and political struggles and, ultimately, the distribution of power or ‘recognition’ in each country. Second, the project aims to explore, through both statistical - analysis and qualitative interviews, how social class is actually lived, experienced and balanced against other pressures and sources of recognition in everyday life, with a focus on three specific nations: the United States, Germany and Sweden. Of - particular interest in this respect is the balancing of desire for recognition through money and education – the two cornerstones of social class in post-industrial capitalist societies – and their associated lifestyles with desires for recognition - and love within the family. The comparative analysis included in both research aims will be guided by the hypothesis that national differences depend on the nature of the welfare regime in operation, especially as it relates to the nature and extent - of workforce feminisation, though the research will also be alive to the possibility of alternative – or no significant – sources of contrast. - - 2021-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - CASSPIN - - - ERC-2015-STG - - - 677055 - - - - - UNIVERSITY OF BRISTOL - UNIVERSITY OF BRISTOL - - - EUR 1 971 866 - - - Consequences of out-group conflict - - - EUR 1 971 866 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The aim of this project is to determine the proximate and ultimate consequences of a fundamental but neglected aspect of sociality: out-group conflict. In a wide range of social species, from ants to humans, group members - invest considerable defensive effort against individual intruders and rival groups. The lasting impacts of these conflicts with conspecifics are poorly understood. I will integrate empirical and theoretical approaches to uncover the effect of - out-group conflict on: (i) individual behaviour, within-group interactions and group decision-making; (ii) steroid hormones that underlie stress, social behaviour and reproduction; (iii) variation in reproductive success arising from maternal - investment and offspring care; and (iv) the evolution of societal structure, cooperation and punishment among group-mates, and weaponry and fortification. I will achieve these ambitious objectives using proven experimental paradigms, innovative - non-invasive sampling, long-term monitoring, and state-of-the-art analytical methods to collect data from two highly tractable model systems that I have established over the last 4 years: a captive-breeding population of the cichlid fish - Neolamprologus pulcher and a habituated wild population of dwarf mongooses (Helogale parvula). I will use some of the same data to inform the assumptions of mathematical models and evolutionary simulations in the development of a rigorous, predictive - framework on out-group conflict, which I will test using both my model systems and phylogenetically controlled meta-analyses across species. The management and consequences of conflict are of major importance to science, human society and global - politics. My novel and inter-disciplinary proposal will not only significantly advance our understanding of the evolution of sociality, but will invigorate a variety of existing research programmes across biology, anthropology, economics, psychology, - and the social and political sciences. - - 2021-06-30, ongoing project - - - 2016-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - Outgroup - - - ERC-2015-CoG - - - 682253 - - - - - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - UNIVERSITY OF BRISTOL - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 1 818 553 - - - Search for a new form of matter: the sterile neutrino - - - EUR 1 818 553 - - - United Kingdom - United Kingdom - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The goal of this proposal is to search for an entirely new kind of matter. This type of matter called a sterile neutrino doesn’t interact with known particles and can only manifest itself through quantum mixing with the three - neutrinos of the standard model, the prevailing theory of particle physics. The known neutrinos are by far the most abundant massive particles in the Universe. More than 70 years after the postulation of the existence of the neutrino, its nature and - fundamental properties remain, paradoxically, poorly known. The discovery of the quantum mixing of neutrinos: neutrino oscillations, was a major surprise as it implied that neutrinos have mass which they do not have in the standard model. In this - context the existence of a sterile neutrino is a natural extension but the discovery of this new state of matter would a profound challenge for the theory to explain. Several new anomalous experimental results have appeared which could be accounted - for by the presence of a light sterile neutrino but each result taken separately is not statistically significant. New oscillation patterns in the neutrino energy spectrum would be a clear signature of the new state but are difficult to measure due - to experimental and background limitations. We propose the most sensitive search to date for this oscillation signature using two key assets: - - 2021-05-31, ongoing project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - SOLID - - - ERC-2015-CoG - - - 682474 - - - - - UNIVERSITAT ZURICH - UNIVERSITAT DES SAARLANDES - UNIVERSITY OF BRISTOL - UNIVERSITA DEGLI STUDI DI PAVIA - Stichting Sanquin Bloedvoorziening - UNIVERSITAIR MEDISCH CENTRUM UTRECHT - CONSORCI INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - ARIVIS AG - EPIGEM LIMITED - Nanion Technologies GmbH - OPTOROBOTIX APS - Fundació Institut de Recerca Contra la Leucemia Josep Carreras - - - EUR 3 896 558,64 - - - Regulation of red cell life-span, erythropoiesis, survival, senescence and clearance - - - EUR 3 896 558,64 - - - Switzerland - Germany - United Kingdom - Italy - Netherlands - Netherlands - Spain - France - France - Germany - United Kingdom - Germany - Denmark - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Corinna Hahn - Tel.: +49 681 95 92 3362 - Fax: +49 681 95 92 3370 - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - - Anaemia is the most common pathological condition affecting 1.6 billion individuals worldwide. It thus presents a serious health care problem and an economic burden. Reduction in red blood cell (RBC) number can be caused by - blood loss, diet, stress conditions including endurance sport, and pathologies which are caused by primary genetic aberrations or are secondary to the malfunction of other cell types. Transfusion of RBC, which is often the only cure for severe cases - of anaemia, is associated with risks such as thrombosis and transfusion reactions due to allo-immunisation. There is an unmet need to improve treatment of anaemia through early and accurate diagnosis, targeted treatment, and increased safety and - effectiveness of RBC transfusion. The aim of RELEVANCE is to improve fast and cost-effective diagnosis of the underlying cause of primary anaemia, and to improve treatment options for both general and personalised medicine. We defined five key - objectives: (1) to improve diagnostics of anaemia, particularly for hereditary rare forms of anaemia (RA); (2) to find novel treatments for anaemia that target RBC production, ageing and clearance; (3) to reduce premature loss of RBC following - transfusion; (4) to produce cultured RBC for transfusion; (5) to monitor and optimise RBC function during sport and exercise. RELEVANCE will train 15 early stage researchers (ESR) at four SMEs and eight academic partners, two of whom are at blood - supply centres and two are diagnostic centres for RA. The continuous interactions between the clinic, blood supply centers, basic research, and industry will select for the most relevant unmet medical needs, and will stimulate innovative procedures - that are immediately probed for applicability and validity both in a research and a clinical setting. RELEVANCE will organize three open access summer schools, extending training beyond the ESR of the ITN sustaining the critical number of young - talented professionals in the field. - - 2019-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Switzerland - - - RELEVANCE - - - H2020-MSCA-ITN-2015 - - - 675115 - - - - - UNIVERSITEIT VAN AMSTERDAM - UNIVERSITEIT VAN AMSTERDAM - - - EUR 1 959 690 - - - Psychosystems:Consolidating Network Approaches to Psychopathology - - - EUR 1 959 690 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - I have recently introduced the Network Approach to Psychopathology. This approach is based on the interpretation of mental disorders as causal systems. Such systems have two basic building blocks: symptoms (i.e., problems like - insomnia, fatigue, and concentration problems) and connections between symptoms (i.e., causal and homeostatic relations, such as insomnia → fatigue → concentration problems). Together, these building blocks constitute a network, which can be analyzed - as a complex system. I have successfully used this approach to explain important phenomena in psychopathology research, such as comorbidity, spontaneous recovery, and prevalence differences between disorders. In addition, I have invented techniques - to identify dynamic network structures from time series data, as obtained through experience sampling methodology. This proposal consolidates the Network Approach to Psychopathology through (a) further development and testing of methodologies, and - (b) applications of the model to important research domains in clinical psychology. The project is structured in two postdoc projects and two Ph. D. projects. Postdoc project Network estimation and control develops analysis techniques for the - estimation of large symptom networks. Postdoc project Early warning signals and transitions investigates whether transitions in symptom networks can be predicted using early warning signals, such as critical slowing down. Ph. D. project Resilience - and vulnerability tests the hypothesis that more strongly connected networks are more vulnerable to disorders and investigates whether depressive episodes lead to prolonged changes in network structure. Ph. D. project The dark matter of - psychopathology investigates the role of "anti-symptoms" – networks of positive factors that have buffering effects on symptom networks. This new approach to the study of psychopathology aims to establish a breakthrough in the understanding of mental - disorders. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - Psychosystems - - - ERC-2014-CoG - - - 647209 - - - - - UNIVERSITEIT VAN AMSTERDAM - UNIVERSITEIT VAN AMSTERDAM - - - EUR 1 391 324 - - - Quantification and modality in the realm of questions - - - EUR 1 391 324 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The interpretation of linguistic expressions has been investigated from various theoretical perspectives, ranging from linguistics and philosophy to logic and cognitive science, leading to many applications in computer - science. At the heart of this enterprise is a simple yet powerful notion of meaning as truth-conditional content. Despite its merits, this view has a fundamental limitation: while suitable for statements, it does not apply to other sentence types, - like questions. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - QuModQu - - - ERC-2015-STG - - - 680220 - - - - - UNIVERSITEIT VAN AMSTERDAM - UNIVERSITEIT VAN AMSTERDAM - - - EUR 1 256 624 - - - Moonshine and String Theory - - - EUR 1 256 624 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The purpose of the proposed research is to forward the understanding of the umbral moonshine discovered recently by myself. I plan to study it in the context of string theory. Moreover, I aim to use this new discovery to gain - a deeper understanding of certain fundamental aspects of the theory. - - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - MST - - - ERC-2014-STG - - - 640159 - - - - - UNIVERSITY OF BRISTOL - UNIVERSITY OF BRISTOL - - - EUR 1 863 321 - - - Effects of maternal gestational adiposity on fetal development and perinatal, postnatal and next generation health. - - - EUR 1 863 321 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Pregnant women who are overweight/obese have increased risks of adverse perinatal outcomes, and of having offspring who are subsequently overweight/obese. A potentially important consequence of this is that it will drive the - obesity epidemic across generations. Evidence from animal models supports this, but it has not been explored in humans. Furthermore, we need to know the mechanisms linking maternal adiposity to adverse offspring and next generation outcomes in order - to develop preventive interventions. - - - 2020-10-31, ongoing project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - ObesityDevelop - - - ERC-2014-ADG - - - 669545 - - - - - UNIVERSITY OF BRISTOL - UNIVERSITY OF BRISTOL - - - EUR 2 397 430 - - - Global land ice, hydrology and ocean mass trends - - - EUR 2 397 430 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Sea level rise will be one of the most serious and costly consequences of future climate change. Constraining the sources and sinks of sea level change is essential for understanding the drivers of past variations and for - improving predictions of future behaviour. Matching estimates of sea level rise with the components that affect it is a long standing problem in geosciences spanning multiple disciplines: oceanography, glaciology, hydrology and solid Earth physics. - Traditionally, each part of the problem has been tackled separately using different data, techniques and physical understanding. This is because of the challenge in determining just one component but also because of the different expertise and - understanding within the various communities. The proposed research will, for the first time, tackle all components simultaneously. I will combine all the relevant observations (both from satellites and in situ) with physical principles of the - coupled system to solve for all components of the sea level budget. First, I will produce a data-driven estimate for glacio-isostatic adjustment that is independent of any assumptions about Earth structure or ice loading history. Second, I will - partition the sea level budget into its steric, hydrological, cryospheric and solid earth components for 1981-2020. Third, I will apply the methods and datasets to re-evaluate the 20th Century sea level record. These advances will also result in the - determination of regional mass trends of land ice and hydrology over a ~30 year period. In the process of attaining these goals in geosciences, I will also develop state of the art techniques for statistical inference of Big Data. I have developed - and tested the approach, using a subset of the data, for the Antarctic ice sheet. The approach is unique, global in scale and will address fundamental problems across four different disciplines in geosciences, as well as advancing techniques in - statistical inference and computer science. - - 2021-07-31, ongoing project - - - 2016-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - GlobalMass - - - ERC-2015-AdG - - - 694188 - - - - - KING'S COLLEGE LONDON - KING'S COLLEGE LONDON - - - EUR 2 274 225 - - - The values of French language and literature in the European Middle Ages - - - EUR 2 274 225 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Two questions about linguistic identity lie at the heart of this project. What is the relation historically between language and identity in Europe? How are cognate languages demarcated from each other? Normative models of - national languages helped shape Europe. Yet they did not become hegemonic until the 19th century. Indeed, they were imposed (not always successfully) on a linguistic map of Europe more fluid and complex than most histories of national languages - allow. In the Middle Ages multilingualism was common, as was the use of non-local languages, notably Latin, but also French. This project undertakes a revaluation of the nature and value of the use of French in Europe during a crucial period, - 1100-1450, less in terms of its cultural prestige (the traditional focus of scholarship) than of its role as a supralocal, transnational language, particularly in Western Europe and the Eastern Mediterranean. The project fosters collaboration - between, and cuts across, different intellectual and national scholarly traditions, drawing on expertise in codicology, critical theory, linguistics, literature, and philology; it involves scholars from a range of European countries and North - America, entailing empirical research around a complex and widely disseminated textual tradition vital to medieval understandings of European history and identity, L’Histoire ancienne jusqu’à César. This case study will ground and stimulate broader - speculative reflection on the two core questions concerning linguistic identity. While the project builds on prior critiques of the construction of, and investment in, national languages and literary traditions, it has a broad historical scope, and - will offer an innovative, genuinely international perspective, in terms of both its object of study and method. Indeed, its final aim, through and beyond its consideration of French as a lingua franca, is to interrogate that language’s role in the - emergence of a European identity in the Middle Ages. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - TVOF - - - ERC-2014-ADG - - - 670726 - - - - - UNIVERSITAT KONSTANZ - UNIVERSITAT KONSTANZ - UNIVERSITAET STUTTGART - - - EUR 2 036 750 - - - Active Suspensions with Controlled Interaction Rules - - - EUR 2 036 750 - - - Germany - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Self-propelling, i.e., active colloidal particles constitute a novel class of non-equilibrium systems which exhibit structural and dynamical features similar to those in assemblies of bacteria or other motile organisms. Due to - their reduced complexity, they provide an intriguing chance to understand the formation of dynamical structures in non-equilibrium systems in unprecedented detail. A central question in this rapidly growing field is, how interaction-rules determine - the creation of e.g. swarms or complex networks. In addition to ordinary inter particle and hydrodynamic forces, interaction-rules can be much more complex. For example, they can regulate the particle motility depending on their relative orientation, - their local density or otherwise distinct particle configurations. - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - ASCIR - - - ERC-2015-AdG - - - 693683 - - - - - KOBENHAVNS UNIVERSITET - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - UPPSALA UNIVERSITET - UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA - JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN - EUROPEAN MOLECULAR BIOLOGY LABORATORY - CENTRE EUROPEEN DE RECHERCHE EN BIOLOGIE ET MEDECINE - INSTITUT PASTEUR - SYSTASY BIOSCIENCE GMBH - Novo Nordisk A/S - - - EUR 3 744 859,32 - - - Unraveling Principles of PDZ-mediated Cell Signaling - - - EUR 3 744 859,32 - - - Denmark - France - Sweden - Italy - Germany - Germany - France - France - Germany - Denmark - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - PDZnet will create an innovative European PhD training network focusing on unraveling PDZ domain-mediated signaling networks. The emphasis will be on signaling nodes essential for the development of cancer and diseases of the - nervous system, conditions that affect millions of Europeans and are major societal challenges. PDZ domains are protein and lipid recognizing modules that play a central role in trafficking and organizing diverse cell signaling assemblies, thereby - allowing information to be transmitted from receptors, ion channels and transporters in the cell membrane. PDZ domain mediated interactions are emerging as conceptually novel and promising drug targets, with exciting opportunities for the development - of novel therapies, especially within cancer and brain diseases. We will establish a European multidisciplinary platform integrating a plethora of complementary life science disciplines that range from chemical development of inhibitors to studies in - live animals. The network encompasses 8 academic and 2 industrial beneficiaries as well as one industrial and one academic partner, which are all committed to promote frontline research, innovation and educational activities within the study of PDZ - domain-mediated signal transduction pathways related to brain diseases and cancer. This interdisciplinary network will establish an outstanding training opportunity for Early Stage Researchers, who will be integrated in projects unraveling - intracellular PDZ domain interactomes to provide pertinent information for discovering drug-related interactions. In a comprehensive and integrated training effort, involving a combination of scientific and transferable skills, the students will - receive an interdisciplinary, intersectoral and innovative doctoral training from experienced industrial and academic leaders in well-reputed European Institutions. - - 2020-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Denmark - - - PDZnet - - - H2020-MSCA-ITN-2015 - - - 675341 - - - - - UNIVERSITEIT VAN AMSTERDAM - UNIVERSITEIT VAN AMSTERDAM - - - EUR 2 499 780 - - - Separation Technology for A Million Peaks - - - EUR 2 499 780 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Extremely high separation powers are required to fully characterize complex mixtures that are of crucial importance in many fields, such as life science (including systems biology), food science, renewable energy sources and - feedstocks, and high-tech materials. The STAMP project is aimed at obtaining a peak capacity of one million in liquid-phase analytical separations. Spatial three-dimensional liquid chromatography will be used to achieve this goal. The major advantage - of this technique is that all second-dimension separations and – in a next step – all third-dimension separations are performed in parallel. This allows high-resolution separations to be performed in each dimension, while the total analysis time - remains reasonable. Optical and mass-spectrometric imaging techniques are envisaged as detection methods after printing (STAMPing) the effluent from the 3D separation body on a suitable substrate. The STAMP project also has a number of sub-targets - that will bring additional significant benefits to all the above application fields. - - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Netherlands - - - STAMP - - - ERC-2015-AdG - - - 694151 - - - - - KING'S COLLEGE LONDON - - - EUR 195 454,80 - - - The involvement of epidermal stem cells in spatiotemporal ERK activity propagation - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Stem cells are central to maintenance of mammalian epidermis. This proposal focuses on how stem cells communicate with their microenvironment by intercellular propagation of growth signal. I will investigate the involvement of - epidermal stem cells in a novel growth signal propagation pattern I found in my PhD research. In this research, I visualized extracellular signal regulated kinase (ERK) activity in the skin of living mice by FRET-based observation of transgenic mouse - expressing a sensitive biosensor for ERK. By this approach, I found a novel pattern of intercellular ERK activity propagation, which we named SPREAD. In SPREAD, bursts of localized ERK activation concentrically propagated to their surrounding 100 - -300 cells. The timing and location of SPREAD emergence suggested the involvement of epidermal stem cells. To test this possibility I will combine my expertise of FRET imaging with in vivo and in vitro systems for mouse and human keratinocytes in the - host laboratory. By crossing ERK biosensor mice with various mouse strains that marks Lgr5+, Lgr6+, or Lrig1+ stem cells, I will observe whether the centre cells of SPREADs are epidermal stem cells in vivo. In addition, I will culture keratinocytes - expressing the ERK FRET biosensor on an artificially engineered substrate to recapitulate SPREAD in vitro. To study whether SPREADs are also seen in human skin, I will exploit a skin reconstruction system, called organotopic culture. The method - allows culture of keratinocytes on collagen matrices embedded with various fibroblast populations with various densities. The significance of the features of SPREAD (shape, size, amplitude etc.) will be addressed by generating various types of ERK - activity propagation by using light-induced ERK activation system. This approach will bring fresh insights into how stem cells control their local tissue structures via intercellular propagation of growth signal and how microenviromental factors - effect on the propagation pattern. - - 2018-06-26, ongoing project - - - 2016-06-27 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SKINFRET - - - H2020-MSCA-IF-2015 - - - 704587 - - - - - JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - STICHTING VU - UNIVERSITA DEGLI STUDI DI VERONA - WAGENINGEN UNIVERSITY - UNIVERZITA PALACKEHO V OLOMOUCI - QUEEN MARY UNIVERSITY OF LONDON - TURUN YLIOPISTO - PHOTON SYSTEMS INSTRUMENTS SPOL SRO - PHYCOSOURCE SARL - UMEA UNIVERSITET - RIJKSUNIVERSITEIT GRONINGEN - - - EUR 3 866 945,22 - - - Solar Energy to Biomass - Optimisation of light energy conversion in plants and microalgae - - - EUR 3 866 945,22 - - - Germany - France - Netherlands - Italy - Netherlands - Czech Republic - United Kingdom - Finland - Czech Republic - France - Sweden - Netherlands - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In the face of the increasing global consumption of fossil resources, photosynthetic organisms offer an attractive alternative that could meet our rising future needs as clean, renewable, sources of energy and for the - production of fine chemicals. Key to the efficient exploitation of these organisms is to optimise the conversion of Solar Energy into Biomass (SE2B). The SE2B network deals with this optimisation in an interdisciplinary approach including molecular - biology, biochemistry, biophysics and biotechnology. Regulation processes at the level of the photosynthetic membranes, integrating molecular processes within individual proteins up to flexible re-arrangements of the membranes, will be analysed as a - dynamic network of interacting regulations. SE2B will yield information about the similarities and differences between cyanobacteria, green algae, diatoms and higher plants, the organisms most commonly employed in biotechnological approaches - exploiting photosynthetic organisms, as well as in agriculture. - - - 2020-02-29, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - SE2B - - - H2020-MSCA-ITN-2015 - - - 675006 - - - - - UNIVERSITY OF BRISTOL - - - EUR 183 454,80 - - - Main group chemistry, inorganic polymers, catalysis, silicon- and phosphorus-based polymers - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Inorganic polymers are of widespread interest as a result of their useful combination of physical and chemical properties, which offer exciting opportunities for their use as advanced materials for many different applications. - In the proposed research state-of-the-art strategies worked out in organic catalysis will be applied for the first time to main group substrates to form main group element-element (specifically Si–O and PV–O) bonds, targeting efficient new routes to - inorganic polymers that involve mild reaction conditions and permit microstructure control. Once formed, the new polymeric materials will be characterized in detail and potential applications explored. To achieve these objectives Dr. Lipeng Wu, an - exceptionally talented young scientist from China who performed his Ph.D. and postdoc in top organic catalysis groups in Germany (Matthias Beller, Rostock) and the USA (F. Dean Toste, UC Berkeley), will work in the internationally leading research - group of Prof. Ian Manners (Bristol, UK) with expertise in catalysis with main group substrates, inorganic polymers, and polymer materials science. Armed with the new knowledge and experience gained, following the fellowship Dr. Wu aims to obtain an - academic position in China where catalysis with main group compounds and inorganic polymers play a key role. - - 2018-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - LWIMT - - - H2020-MSCA-IF-2015 - - - 701972 - - - - - UNIVERSITEIT VAN AMSTERDAM - - - EUR 162 864,60 - - - Unconditional parental regard: Its nature and its consequences - - - EUR 162 864,60 - - - Netherlands - - - Higher or Secondary Education Establishments - - Unconditional parental regard refers to parents accepting children for who they are, even when they disapprove of children’s achievements (e.g., school grades). Psychological theory holds that children internalize - unconditional regard to feel worthy for who they are. Children may thus feel less pressured to excel, and become more intrinsically motivated and less afraid of failure. However, unconditional regard has received little empirical scrutiny. The main - objectives of this 24-month Marie Curie IF-GF are (a) to investigate the nature and consequences of unconditional parental regard in childhood; (b) to provide advanced training in experimental research (pioneered by the partner organization) and - intervention development (pioneered by the beneficiary); and (c) to provide advanced training in soft skills and entrepreneurial skills. Thus, it brings the applicant closer to mid-term career goals of becoming a leading expert and establishing a - research group in the field of socialization—a field where the EU currently lags behind the US. In this project, one study explores how parents express unconditional regard (Study 1). Two experiments investigate the causal effects of unconditional - regard on children’s self-worth and motivation (Study 2-3). An observational-longitudinal study investigates whether the effects of unconditional regard sustain over time in children’s lives (Study 4). The studies will be conducted in specialized - laboratories under supervision of leading experts. The project strengthens the EU’s position in the field of socialization, and establishes a long-term cross-disciplinary collaboration between the applicant and participating parties. The results will - have timely societal implications: Contemporary EU youth suffer more ill-being and motivational problems than did previous generations. To help alleviate these problems, the applicant will develop and implement an unconditional-regard intervention in - partnership with EU health-care professionals. - - 2018-05-31, ongoing project | - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Netherlands - - - UPR - - - H2020-MSCA-IF-2015 - - - 705217 - - - - - KARLSTADS UNIVERSITET - WIRTSCHAFTSUNIVERSITAT WIEN - USECON THE USABILITY CONSULTANTS GMBH - JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN - UNABHAENGIGES LANDESZENTRUM FUER DATENSCHUTZ - UNISCON UNIVERSAL IDENTITY CONTROL GMBH - TEL AVIV UNIVERSITY - UNIVERSITY COLLEGE LONDON - CRONTO LIMITED - - - EUR 3 376 517,40 - - - Privacy and Usabiliy - - - EUR 3 376 517,40 - - - Sweden - Austria - Austria - Germany - Germany - Germany - Israel - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - With the rapid accumulation and processing of personal data by numerous organizations, it is of paramount importance to protect people from adverse uses of their data, while allowing them to enjoy the benefits the use of these - data can possibly provide. This is the question of protecting citizens’ privacy, while enabling them to make informed decisions regarding their actions with privacy implications. - - 2019-11-30, ongoing project - - - 2015-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Sweden - - - Privacy.Us - - - H2020-MSCA-ITN-2015 - - - 675730 - - - - - UNIVERSITY OF BRISTOL - UNIVERSITY OF BRISTOL - - - EUR 2 436 379 - - - Efficient, Flexible Synthesis of Molecules with Tailored Shapes: from Photo-switchable Helices to anti-Cancer Compounds - - - EUR 2 436 379 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The creation of new molecular entities and subsequent exploitation of their properties is central to a broad spectrum of research disciplines from medicine to materials but progress has been limited by the difficulties - associated with chemical synthesis. We are now proposing a fundamentally new strategy, which has the potential to revolutionise how we conduct complex organic synthesis. The basic C–C bond-forming step involves the reaction of a lithiated carbamate - with a boronic ester to give a homologated boronic ester with complete stereocontrol. Furthermore, the reaction shows >98% efficiency in most cases and can be conducted iteratively and in one pot (up to 9 iterations has been demonstrated with full - stereocontrol). We will now extend this methodology to more functionalised carbamates as this will enable the rapid synthesis of polypropionates, which are amongst the most important classes of biologically active molecules. The robust methodology is - now ripe for transfer to the solid phase as this will enable the preparation of libraries of these molecules. Through applying our assembly-line-synthesis methodology to complex molecules with diverse structures, we will demonstrate its scope, - robustness, and full potential. The methodology enables stereochemistry to be ‘dialled in’ to a carbon chain, which in turn controls the conformation and we will exploit this feature in the shape-selective synthesis of molecules. We will explore how - the sense of helical chirality of these molecules can be switched (M to P) just with light. We will target helical molecules with specific groups at specific places for optimum binding to disrupt protein–protein interactions involved in cancer. - Finally, our methodology provides ready access to a family of building blocks that represent common repeat units found in polyketides. By combining these building blocks iteratively using lithiation-borylation, we should be able to rapidly and - reliably prepare complex natural products. - - 2020-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - FRESCO - - - ERC-2014-ADG - - - 670668 - - - - - THE UNIVERSITY OF NOTTINGHAM - ROENTDEK - HANDELS GMBH - JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN - PHOTEK LIMITED - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - AARHUS UNIVERSITET - CONSIGLIO NAZIONALE DELLE RICERCHE - FORSCHUNGSVERBUND BERLIN EV - Société civile SYNCHROTRON SOLEIL - - - EUR 3 180 705,84 - - - Angular studies of photoelectrons in innovative research environments - - - EUR 3 180 705,84 - - - United Kingdom - Germany - Germany - United Kingdom - France - Denmark - Italy - Germany - France - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - - In the ASPIRE project, whose academic and industrial beneficiaries are world leading in their complementary fields of expertise, the overarching research goal is the measurement of photoelectron angular distributions (PADs) in - the “molecular frame” (MF) of systems of biological relevance. These MF-PADs can be interpreted as electron diffraction patterns, achieved by “illuminating the molecule from within”, and enable the shapes and motions of individual molecules to be - interrogated. Such knowledge is needed for the development of new medicines (the shapes of drug molecules dictate their function) and new materials (efficient solar cells can be constructed if energy dissipation processes in molecules are - understood). Progress in this area is highly technologically driven, requiring high repetition rate, short wavelength light sources and fast detectors. The input of private sector beneficiaries is therefore critical to the scientific objectives, as - well as to the enhanced training environment. Work packages on advanced light source and detector developments will feed into the overall goal through secondments, regular virtual meetings and face-to-face network meetings. The symbiosis of the - developments that will take place in ASPIRE will create a research and training environment that is world-leading and optimally tailored to capitalise, for example, on the investment that has been made in the European XFEL facility. The ESRs will be - trained in world-leading laboratories and will benefit from the exchange of best practice among beneficiaries and partners, and from unique training events. ASPIRE will therefore ensure that European research remains competitive in the global market, - and that the trained researchers will be uniquely well-placed to contribute to the development of novel instrumentation in the future. - - 2020-02-29, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - ASPIRE - - - H2020-MSCA-ITN-2015 - - - 674960 - - - - - PERCUROS BV - ACADEMISCH ZIEKENHUIS LEIDEN - TECHNISCHE UNIVERSITEIT DELFT - UNIVERSITA DEGLI STUDI DI CAMERINO - TECOBIOSCIENCES GMBH - UNIVERSITEIT VAN AMSTERDAM - UNIVERSITETET I BERGEN - HELSE BERGEN HF*HAUKELAND UNIVERSITY HOSPITAL - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - THE UNIVERSITY OF SHEFFIELD - UNIVERSITEIT MAASTRICHT - JENACELL GMBH - MEDRES-MEDICAL RESEARCH GMBH - ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM - - - EUR 3 922 309,44 - - - Image-Guided Surgery (IGS) and Personalised Postoperative Immunotherapy To Improving Cancer Outcome - - - EUR 3 922 309,44 - - - Netherlands - Netherlands - Netherlands - Italy - Germany - Netherlands - Norway - Norway - Switzerland - United Kingdom - Netherlands - Germany - Germany - Netherlands - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - The basic concept of our proposal is to develop nanoparticle-based encapsulated libraries of different immunotherapeutic biomolecules for treatment after surgery as part of a novel cancer management strategy. The current - state-of-art for the management of cancer starts with surgery, after identification of an accessible tumour mass. Surgery remains an effective treatment option for many types of cancer today and it is considered curative treatment for most solid - tumours. It forms part of a multidisciplinary approach used in conjunction with radiotherapy or chemotherapy. These approaches, however, have several limitations, including inability of surgical resection to affect distal metastatic disease, toxicity - to healthy tissues with chemotherapy and lack of effectiveness of radiation therapy in more aggressive tumours. The observation that cancer can relapse months or years after initial surgery implies that micrometastases still resides within the body - in a latent state. Our proposal is to take cancer therapy to beyond state-of-art by implementing techniques which will take us into new directions. This includes a) new methods to identify immune gene profiles and biomarkers b) transgenic mouse - models where the complex interactions that underlie immune function can be visualised as multiplexed events in real time and c) the use of nanoparticle-based libraries of immune modulating reagent combinations. There are three key objectives within - this project: i) to use immune gene signatures to monitor disease progression and therapeutic efficacy of immunotherapy combinations on nanoparticle-based platforms, ii) to optimise the platform to encapsulate libraries of immune components for more - personalised, accurate and timely delivery of the payload to its intended target and iii) to optimise the overall cancer management process of image-guided surgery followed by postoperative immunotherapy so that we can ultimately provide a lifetime - of protection against cancer. - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Netherlands - - - ISPIC - - - H2020-MSCA-ITN-2015 - - - 675743 - - - - - THE UNIVERSITY OF BIRMINGHAM - ACADEMISCH ZIEKENHUIS GRONINGEN - UNIVERSITAT DE BARCELONA - JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN - - - EUR 2 572 664,04 - - - Deciphering the Metabolism of Haematological Cancers - - - EUR 2 572 664,04 - - - United Kingdom - Netherlands - Spain - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - It has long been realised that metabolism is central to cellular development, proliferation and homeostasis. Collectively, aberrations in metabolism are now recognised as a major hallmark of cancer, opening new avenues for - personalised medicine. As haematological malignancies are multi-factorial diseases, our main emphasis will be on the integration of biomedical multi-omics data and computational systems modelling with the ultimate aim to understand metabolic - regulation in haematological cancers. HaemMetabolism is design to unravel the regulatory mechanisms that link cell cycle control and metabolism. For this we will screen a panel of haematological cancer cell lines for the metabolic phenotypes and - against a library of inhibitors. Gene-function analyses will be performed using shRNA libraries directed against key metabolome regulators. Validation will occur in primary patient samples in vitro and in vivo in preclinical humanized niche xenograft - mouse models. A systems biomedicine approach will be integrated build genome-scale transcriptional models that explain deregulated metabolic pathways relevant for the development of haematological malignancies. This work will not only open new - avenues for drug discovery but will also provide a multi-disciplinary framework for student training in biomedical technologies. - - 2019-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-EJD - Marie Skłodowska-Curie Innovative Training Networks (ITN-EJD) - - - MSCA-ITN-EJD - European Joint Doctorates - - - United Kingdom - - - HaemMetabolome - - - H2020-MSCA-ITN-2015 - - - 675790 - - - - - UNIVERSITY OF BRISTOL - ECOLE CENTRALE DE LYON - UNIVERSITY OF NORTHUMBRIA AT NEWCASTLE - UNIVERSITAET INNSBRUCK - HELMHOLTZ ZENTRUM POTSDAM DEUTSCHESGEOFORSCHUNGSZENTRUM GFZ - EIDGENOESSISCHE FORSCHUNGSANSTALT WSL - MBIOINFORM APS - UNIVERZA V LJUBLJANI - INSTITUTUL DE BIOLOGIE BUCURESTI - HASKOLINN A AKUREYRI - ENOVEO SARL - ABERYSTWYTH UNIVERSITY - DR. BRILL + PARTNER GMBH INSTITUT FUER HYGIENE UND MIKROBIOLOGIE - - - EUR 3 897 006,48 - - - Microorganisms in Warming Arctic Environments - - - EUR 3 897 006,48 - - - United Kingdom - France - United Kingdom - Austria - Germany - Switzerland - Denmark - Slovenia - Romania - Iceland - France - United Kingdom - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The Arctic plays a key role in the Earth’s climate system and is an area of growing strategic importance for European policy. In this ETN, we will train the next generation of Arctic microbiology and biogeochemistry experts - who, through their unique understanding of the Arctic environment and the factors that impact ecosystem and organism response to the warming Arctic, will be able to respond to the need for leadership from public, policy and commercial interests. The - training and research programme of MicroArctic is made up of seven interlinked Work Packages (WP). WP1 to WP4 are research work packages at the cutting edge of Arctic microbiology and biogeochemistry and these will be supported by three overarching - WPs (WP5-7) associated with the management, training and dissemination of results. WP1 will deliver information about the role of external inputs (e.g., atmospheric) of nutrients and microorganism that drive biogeochemical processes in relation to - annual variation in Arctic microbial activity and biogeochemical processes. WP2 will explore ecosystem response on time scales of 100s of years to these inputs using a chrnosequence approach in the already changing Arctic. The effect of time and - season and the warming of the Arctic on ecosystem functioning and natural resources will be quantified through geochemical analyses and next generation multi-omics approaches. Complementing WP1 and WP2, WP3 will focus on organism response and - adaptation using a range of biochemical, molecular, experimental and culturing approaches. WP4 will address specific applied issues such as colonisation by pathogenic organisms and biotechnological exploitation of Arctic ecosystems. MicroArctic will - bring together interdisciplinary experts from both the academic and non-academic sectors across Europe into a network of 20 Institutions across 11 countries. - - 2020-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - MicroArctic - - - H2020-MSCA-ITN-2015 - - - 675546 - - - - - UNIVERSITY OF HULL - UNIVERSIDAD DE GRANADA - ASSOCIAZIONE ORLANDO - UNIVERSITEIT UTRECHT - UNIVERSIDAD DE OVIEDO - UNIWERSYTET LODZKI - ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA - KOZEP-EUROPAI EGYETEM - - - EUR 3 719 102,04 - - - GRACE: Gender and Cultures of Equality in Europe - - - EUR 3 719 102,04 - - - United Kingdom - Spain - Italy - Netherlands - Spain - Poland - Italy - Hungary - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The aim of the GRACE (Gender and Cultures of Equality in Europe) project is to systematically investigate the cultural production of gender equalities within Europe. Extending the success of GEMMA, the Erasmus Mundus ‘Masters - of Excellence’ in Women’s and Gender Studies, the central objective of GRACE is to become the programme of reference for innovative interdisciplinary doctoral training for early career researchers. Previous scholarly work focuses on European gender - equality policies. GRACE draws on innovative and interdisciplinary methodologies to investigate an under-examined aspect of those processes, namely the production of cultures of equality that underpin, enable and constrain those changing policy and - legislative frameworks. Our methodological approach understands culture as neither normative frameworks nor ways of representing the world, but more fundamentally as the process through which people create the worlds they inhabit. The GRACE project - will recruit, employ and provide advanced training for 15 ESRs who will research the production of cultures of gender equality across five specific sites where cultures of gender equalities are produced and contested by differently situated social - agents. These five sites form the core of our research and training Work Packages, and are focused as follows: mediated cultures of gender equality (WP 1); urban cultures of gender equality (WP 2); intellectual and activist cultures of gender - equality (WP 3); textual and artistic cultures of gender equality (WP 4); employing cultures of gender equality (WP 5). In sum, GRACE is designed to: equip the next generation of ESRs to play a leading role in developing advanced techniques for - investigating the production of cultures of gender equality; translate creative and critical capacities into innovative cultural practices within and beyond academia; and enable them to take up positions as experts in producing new gender equalities - cultures. - - 2019-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - GRACE - - - H2020-MSCA-ITN-2015 - - - 675378 - - - - - UNIVERSITY OF BRISTOL - UNIVERSITY OF BRISTOL - - - EUR 1 548 738 - - - New Catalytic Asymmetric Strategies for N-Heterocycle Synthesis - - - EUR 1 548 738 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Medicinal chemistry requires more efficient and diverse methods for the asymmetric synthesis of chiral scaffolds. Over 60% of the world’s top selling small molecule drug compounds are chiral and, of these, approximately 80% - are marketed as single enantiomers. There is a compelling correlation between drug candidate “chiral complexity” and the likelihood of progression to the marketplace. Surprisingly, and despite the tremendous advances made in catalysis over the past - several decades, the “chiral complexity” of drug discovery libraries has actually decreased, while, at the same time, for the reasons mentioned above, the “chiral complexity” of marketed drugs has increased. Since the mid-1990s, there has been a - notable acceleration of this “complexity divergence”. Consequently, there is now an urgent need to provide efficient processes that directly access privileged chiral scaffolds. It is our philosophy that catalysis holds the key here and new processes - should be based upon platforms that can exert control over both absolute and relative stereochemistry. In this proposal we outline the development of a range of N-heteroannulation processes based upon the catalytic generation and trapping of unique - or unusual classes of organometallic intermediate derived from transition metal insertion into C-C and C-N sigma-bonds. We will provide a variety of enabling methodologies and demonstrate applicability in flexible total syntheses of important natural - product scaffolds. The processes proposed are synthetically flexible, operationally simple and amenable to asymmetric catalysis. Likely starting points, based upon preliminary results, will set the stage for the realisation of aspirational and - transformative goals. Through the study of the organometallic intermediates involved here, there is potential to generalise these new catalytic manifolds, such that this research will transcend N heterocyclic chemistry to provide enabling methods for - organic chemistry as a whole. - - 2020-03-31, ongoing project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - CatHet - - - ERC-2014-STG - - - 639594 - - - - - UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK - JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN - ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON - UNIVERSITY OF BATH - FACHHOCHSCHULE NORDWESTSCHWEIZ - H. Lundbeck A/S - MERCK KOMMANDITGESELLSCHAFT AUF AKTIEN - PHARMATEN ANONYMOS VIOMICHANIKI KAI EMPORIKI ETAIREIA PHARMAKEFTIKON KAI KALLYNTIKON PROIONTON - SIRIUS ANALYTICAL INSTRUMENTS LTD - Janssen Pharmaceutica NV - - - EUR 3 856 253,04 - - - Pharmaceutical Education And Research with Regulatory Links: Innovative drug development strategies and regulatory tools tailored to facilitate earlier access to medicines - - - EUR 3 856 253,04 - - - Ireland - Germany - Greece - United Kingdom - Switzerland - Denmark - Germany - Greece - United Kingdom - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The European Pharma industry is a major contributor to EU well-being, both in public health and economic (sales >200 billion €/year) terms. To maintain global leadership, it must respond to challenges from low-cost - producers e.g. China by bringing new drug molecules to market in a streamlined, cost-effective manner. This strategy is underscored by recent initiatives of European regulators to expedite the approval of “breakthrough drugs” so patients can gain - earlier access to life-saving drugs. To realise these goals, scientists with an integral understanding of drug development and regulatory approval processes are urgently needed. - - - 2020-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Ireland - - - PEARRL - - - H2020-MSCA-ITN-2015 - - - 674909 - - - - - UNIVERSITEIT VAN AMSTERDAM - UNIVERSITEIT VAN AMSTERDAM - - - EUR 1 499 875 - - - Fickle Formulas. The Political Economy of Macroeconomic Measurement - - - EUR 1 499 875 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Macroeconomic indicators are integral to economic governance. Measurements of growth, unemployment, inflation and public deficits inform policy, for example through growth targets and the inflation-indexation of wages. These - indicators tell us “how economies are doing” and citizens often punish politicians who fail to deliver on them. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - FICKLEFORMS - - - ERC-2014-STG - - - 637683 - - - - - SCIENCE AND TECHNOLOGY FACILITIES COUNCIL - - - EUR 2 548 800 - - - Rutherford International Fellowship Programme - - - EUR 5 097 600 - - - United Kingdom - - - Research Organisations - - The Rutherford International Fellowship Programme (RIFP) will be a new, high-quality Post-Doctoral scheme aimed at research excellence and promoting researcher mobility and training. - - 2020-06-30, ongoing project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2014-FP - Marie Skłodowska-Curie Co-funding of regional, national and international programmes (COFUND-FP) - - - MSCA-COFUND-FP - Fellowship programmes - - - United Kingdom - - - RIFP - - - H2020-MSCA-COFUND-2014 - - - 665593 - - - - - KING'S COLLEGE LONDON - KING'S COLLEGE LONDON - - - EUR 1 947 665 - - - Dark Matter and the Early Universe in the LHC Era - - - EUR 1 947 665 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The discovery of a Higgs like particle in its first science run shows that we are truly in the LHC era and when collisions resume we will learn more about the physics of the TeV scale. - - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - DARKHORIZONS - - - ERC-2014-CoG - - - 648680 - - - - - UNIVERSITY OF BRISTOL - UNIVERSITY OF BRISTOL - - - EUR 1 233 672 - - - Cultural Evolution of Kinship Diversity: Variation in Language, Cognition, and Social Norms Regarding Family - - - EUR 1 233 672 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Why do human societies differ in whom they class as family? Why are cousins classed with siblings in some societies but not others? Accounting for the variable ways that cultures classify kin is an enduring puzzle. The VARIKIN - project takes a cultural evolutionary approach to variety and unity and engages different fields–cultural phylogenetics, corpus linguistics, and cross-cultural child development. VARIKIN-Evolution asks how and why does kinship diversity evolve across - cultures and over time? Using comparative phylogenetic modeling of cultural evolution we investigate the dynamics of how kinship terminologies and family norms change in eight language families. Are there “universal” patterns of change, or does local - cultural history and context determine changes in family organisation? How do social norms drive change in kinship terminology? VARIKIN-Usage investigates how people use kinship language by using corpus linguistics, surveys, and interviews to - quantify patterns of usage in spoken and written language. How frequently are kinship terms used in different contexts and what meanings are more prevalent? Do patterns vary between languages, and can the patterns of usage at the individual level be - linked to historical processes of change? VARIKIN-Development investigates how children acquire and understand kinship across cultures. Using participant observation and elicitation tasks, we characterise children’s social learning of kinship in a - small-scale, non-Western community. Are there cross-cultural patterns of acquisition? Can socialisation produce constraints on the kinds of kinship children can learn? These three research directions are united by a coherent framework for the - integration of macro- and micro-evolutionary processes. With a highly multidisciplinary background, the Applicant is uniquely positioned to direct this vanguard project towards a comprehensive understanding of diversity in how we classify our social - worlds. - - 2020-06-30, ongoing project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - VARIKIN - - - ERC-2014-STG - - - 639291 - - - - - UNIVERSITEIT VAN AMSTERDAM - UNIVERSITEIT VAN AMSTERDAM - - - EUR 1 498 352 - - - Data activism: The politics of big data according to civil society - - - EUR 1 498 352 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - With the diffusion of ‘big data’, citizens become increasingly aware of the critical role of information in modern societies. This awareness gives rise to new social practices rooted in technology and data, which I term ‘data - activism’. While activists see massive data collection by governments and businesses as a challenge to civil rights, big data also offer new opportunities for collective action. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - DATACTIVE - - - ERC-2014-STG - - - 639379 - - - - - UNIVERSITAET BERN - JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN - IFOM FONDAZIONE ISTITUTO FIRC DI ONCOLOGIA MOLECOLARE - UNIVERSITE LIBRE DE BRUXELLES - MAGYAR TUDOMANYOS AKADEMIA SZEGEDIBIOLOGIAI KUTATOKOZPONT - UNIVERSITE D'ARTOIS - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - STICHTING VU - THE OPEN UNIVERSITY - GENXPRO GMBH - - - EUR 3 067 402,32 - - - Brain barriers training - - - EUR 3 067 402,32 - - - Switzerland - Germany - Italy - Belgium - Hungary - France - Germany - Switzerland - Netherlands - United Kingdom - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The brain barriers function to protect the central nervous system (CNS) from neurotoxic compounds. By the same traits they unfortunately block delivery of drugs to the CNS thus hindering proper diagnosis and effective - treatment of neurological disorders including Alzheimer’s disease and multiple sclerosis. The unusual complexity of the brain barriers has severely hampered progress in the market of CNS targeting therapeutics. BtRAIN bridges this gap by creating - particular knowledge on vertebrate brain barrier signature genes and their specific roles in regulating brain barrier function in development, health, ageing and disease. Brain barrier signature genes will be identified by combining cross-species and - cross-system brain barrier transcriptome analysis with dedicated bioinformatics. These data will be made available for brain barrier datamining in the userfriendly online platform BBBHub. Within BtRAIN, the side-by-side comparison of a unique and - broad armamentarium of different vertebrate in vitro and in vivo brain barrier models will allow to develop and validate particular in vitro brain barrier models that are suited to reliably predict brain barrier function in vivo. Combined with an - accompanying in depth analysis of the pathological alterations of the brain barriers during neurological disorders BtRAIN will create unique knowledge to overcome the unmet need for the development of diagnostic and therapeutic tools able to breach - the brain barriers. In BtRAIN 12 academic, 6 non-academic partners and 1 European network will jointly train young researchers at unique interfaces of brain barrier research, bioinformatics, business development and science communication for an - international research or entrepreneur career. To create this expert pool is the motivation for the involved partners as it will advance the Euopean capacity to bring innovative approaches to the untapped potential of the CNS therapeutic market. - - 2019-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Switzerland - - - BtRAIN - - - H2020-MSCA-ITN-2015 - - - 675619 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - IN Srl - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - WEIZMANN INSTITUTE OF SCIENCE - EVOGENE LTD - - - EUR 4 871 410 - - - Transforming the future of agriculture through synthetic photorespiration - - - EUR 4 871 410 - - - Germany - Italy - United Kingdom - Israel - Israel - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - For a new green revolution to feed the continually increasing population, agriculture productivity will have to be significantly improved. Photorespiration represents a big challenge in this respect, because it dissipates - energy and leads to the futile loss of CO2, thereby limiting plant growth yield. Implementing an efficient metabolic bypass for photorespiration can therefore increase the photosynthetic efficiency of many cultivated crops. Several such routes were - previously proposed. However, these routes were limited to existing enzymes and pathways and provided only partial improvement. Here, we propose a radically different approach: to engineer entirely novel CO2-neutral or CO2-positive photorespiration - bypasses based on novel enzyme chemistry that support significantly higher agricultural yields. These bypass routes could support 60% higher biomass yield per turn of the Calvin Cycle and >30% higher yield per ATP. Our project innovatively - integrates different research disciplines and combines academic research with industrial implementation. In silico studies will integrate biochemical logic and pathway modelling to explore all possible photorespiration pathways and identify the most - efficient routes. In vitro research will establish novel enzyme functions via enzyme engineering and directed evolution. Full pathways will be reconstituted and optimized in vitro using a novel mass spectrometry based platform. High in vivo activity - will be selected by implementing the pathways in engineered E. coli strains. Enhanced photosynthetic efficiency will be demonstrated in cyanobacteria expressing the synthetic pathways. Finally, the most promising synthetic pathways will be - implemented in higher plants and growth phenotypes will be monitored. The proposed project comprises a significant advance in synthetic biology – applying biochemical principles to modify the very core of carbon metabolism with synthetic pathways - that carry multiple novel enzymatic functions. - - 2020-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-1-2014 - FET-Open research projects - - - RIA - Research and Innovation action - - - Germany - - - FutureAgriculture - - - H2020-FETOPEN-2014-2015-RIA - - - 686330 - - - - - UNIVERSITY OF BRISTOL - UNIVERSITY OF BRISTOL - - - EUR 2 499 938 - - - Implementing Multi-Party Computation Technology - - - EUR 2 499 938 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The goal of IMPaCT is to turn Multi-Party Computation (MPC) from a stage in which we are beginning to obtain practical feasibility results, to a stage in which we have fully practical systems. It has long been acknowledged - that MPC has the potential to provide a transformative change in the way security solutions are enabled. As it presently stands this is currently only possible in limited applications; deployments in restricted scenarios are beginning to emerge. - However, in turning MPC into a fully practical technology a number of key scientific challenges need to be solved; many of which have not yet even been considered in the theoretical literature. The IMPaCT project aims to address this scientific gap, - bridge it, and so provide the tools for a future road-map in which MPC can be deployed as a widespread tool, as ubiquitous as encryption and digital signatures are today. - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - IMPaCT - - - ERC-2015-AdG - - - 690978 - - - - - UNIVERSITEIT VAN AMSTERDAM - UNIVERSITEIT VAN AMSTERDAM - - - EUR 1 479 515 - - - Profiling and targeting news readers – implications for the democratic role of the digital media, user rights and public information policy - - - EUR 1 479 515 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In the digital media environment, user attention is scarce and competition for ‘eyeballs’ is fierce. Profiling and targeting readers with customised news and advertisements that match their individual interests is widely seen - as a solution. The personalization of news media content enables new financing strategies and means to capture the audience’s attention. But personalisation is also part of a more fundamental paradigm shift in the media’s role from public interest - intermediary to personal information coach. This research will answer critical questions about the implications for individual users and contribute to a new normative theory of the role of personalised media in a democratic society. - - 2020-07-31, ongoing project - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - PersoNews - - - ERC-2014-STG - - - 638514 - - - - - ASTON UNIVERSITY - LZH LASER ZENTRUM HANNOVER E.V. - FUNDACIO INSTITUT DE CIENCIES FOTONIQUES - UNIVERSITAT DE BARCELONA - AXOL BIOSCIENCE LTD - Kite Innovation (Europe) Limited - - - EUR 3 225 890,50 - - - Custom architecturally defined 3D stem cell derived functional human neural networks fortransformative progress in neuroscience and medicine - - - EUR 3 225 891,25 - - - United Kingdom - Germany - Spain - Spain - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The development of methods to isolate and generate human stem cells along with technology to selectively differentiate them into specific cell and tissue types has excited many with the promise of the ability to study human - cell function and utilise them for regeneration in disease and trauma. However, to date, attempts to develop regenerative brain and central nervous system therapies have been disappointing, with the introduced stem cell derived neurons not - integrating nor signalling physiologically with endogenous cells. A major confounding issue has been that derived neurons are grown in two dimensions, which does not mimic the in vivo three dimensional interactions nor the myriad developmental cues - they would receive in vivo. - - - 2019-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-1-2014 - FET-Open research projects - - - RIA - Research and Innovation action - - - United Kingdom - - - MESO_BRAIN - - - H2020-FETOPEN-2014-2015-RIA - - - 713140 - - - - - UMEA UNIVERSITET - THE UNIVERSITY OF MANCHESTER - INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE - SCIENCE AND TECHNOLOGY FACILITIES COUNCIL - - - EUR 3 907 375 - - - Parallel Numerical Linear Algebra for Future Extreme-Scale Systems - - - EUR 3 907 375 - - - Sweden - United Kingdom - France - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - - The NLAFET proposal is a direct response to the demands for new mathematical and algorithmic approaches for applications on extreme scale systems, as identified in the FETHPC work programme and call. This project will enable a - radical improvement in the performance and scalability of a wide range of real-world applications relying on linear algebra software, by developing novel architecture-aware algorithms and software libraries, and the supporting runtime capabilities to - achieve scalable performance and resilience on heterogeneous architectures. The focus is on a critical set of fundamental linear algebra operations including direct and iterative solvers for dense and sparse linear systems of equations and eigenvalue - problems. Achieving this requires a co-design effort due to the characteristics and overwhelming complexity and immense scale of such systems. Recognized experts in algorithm design and theory, parallelism, and auto-tuning will work together to - explore and negotiate the necessary tradeoffs. - - - 2018-10-31, ongoing project | - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.2."> - - - FETHPC-1-2014 - HPC Core Technologies, Programming Environments and Algorithms for Extreme Parallelism and Extreme Data Applications - - - RIA - Research and Innovation action - - - Sweden - - - NLAFET - - - H2020-FETHPC-2014 - - - 671633 - - - - - UNIVERSITEIT VAN AMSTERDAM - UNIVERSITEIT VAN AMSTERDAM - - - EUR 1 999 830 - - - Becoming Men: Performing responsible masculinities in contemporary urban Africa - - - EUR 1 999 830 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This anthropological study examines the reconfiguration of masculinities in urban Africa over the last 30 years. Focusing on how practices and discourses of empowerment and equality shape male subjectivities, this study builds - upon a significant body of nuanced research on masculinities in Africa. Since the mid-1980s academic and public discourses have depicted African masculinity as both precarious and predatory. Economic insecurity, urbanization, shifting gender norms, - and growing gender parity have accompanied claims that African masculinity is ‘in crisis’. More recently, new stories of urban men embracing responsible fatherhood, condemning intimate partner violence, and demanding homosexual rights have emerged as - exemplars of progressive possibility. To disentangle these seemingly competing claims about African masculinities and shed light on the scientific, political, and economic projects that shape them, this research theorises that the discourses and - practices that pathologise and politicise masculinity are simultaneously performing and producing gendered selves on multiple scales in the name of gender equality. Recently, ‘male involvement’ has become a rallying cry throughout the vast global - development assemblage, around which governments, NGOs, research networks, activists, and local communities fight gender inequality to promote health, economic development, and human rights. In this research, a range of male-involvement initiatives - provides a lens through which to study how masculinities are diversely imagined, (re)configured, and performed through men’s engagements with this assemblage, in both its local and global manifestations. Multi-sited ethnographic research will focus - on six cities where the PI has active research ties: Nairobi and Kisumu, Kenya; Johannesburg and Durban, South Africa; and Dar es Salaam and Mwanza, Tanzania. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - Becoming Men - - - ERC-2014-CoG - - - 647314 - - - - - UNIVERSIDAD DE BURGOS - AGENZIA NAZIONALE PER LE NUOVE TECNOLOGIE, L'ENERGIA E LO SVILUPPO ECONOMICO SOSTENIBILE - CONSORZIO INTERUNIVERSITARIO PER LO SVILUPPO DEI SISTEMI A GRANDE INTERFASE - MISKOLCI EGYETEM - PANEPISTIMIO PATRON - MBN NANOMATERIALIA SPA - ADVAMAT SRO - ADMATIS KUTATO, GYARTO ES KERESKEDELMI KORLATOLT FELELOSSEGU TARSASAG - BRIMATECH SERVICES GMBH - AEROSPACE & ADVANCED COMPOSITES GMBH - EASN Technology Innovation Services BVBA - - - EUR 2 698 062,50 - - - Innovative Coarsening-resistant Alloys with enhanced Radiation tolerance and Ultra-fine -grainedStructure for aerospace application - - - EUR 2 698 062,50 - - - Spain - Italy - Italy - Hungary - Greece - Italy - Czech Republic - Hungary - Austria - Austria - Belgium - - - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - ICARUS proposes a new thermodynamic methodology able to identify the elements and the relative chemical composition allowing a nanocrystalline state to occupy a relative minimum of the Gibbs free energy, which makes the - nanostructure reasonably stable against coarsening. This approach will be integrated, in synergy with multiscale and thermodynamic (Nano-Calphad) modeling, in order to implement a High-Throughput Screening (HTS) tool that will open a new horizon of - discovery and exploration of multinary thermal stable nanocrystalline alloys, exhibiting superb tailored properties. ICARUS brings a radically new concept by addressing a still unsolved problem in the stabilization of nanocrystalline alloys. The - materials discovery approach of ICARUS will be synergistic with the forefront industrial production technologies of nanomaterials and alloys. - - - 2019-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-1-2014 - FET-Open research projects - - - RIA - Research and Innovation action - - - Spain - - - ICARUS - - - H2020-FETOPEN-2014-2015-RIA - - - 713514 - - - - - UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA - UNIVERSITY OF BRISTOL - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - CONSIGLIO NAZIONALE DELLE RICERCHE - UNIVERSITAT WIEN - UNIVERSITAET PADERBORN - UNIVERSITAET ULM - UNIVERSITE LIBRE DE BRUXELLES - UNIVERSITY OF SOUTHAMPTON - - - EUR 2 681 713,75 - - - Quantum Simulation on a Photonic Chip - - - EUR 2 681 713,75 - - - Italy - United Kingdom - United Kingdom - Italy - Austria - Germany - Germany - Belgium - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Simulation is a fundamental computational tool for modern science with applications ranging from drug design to materials science. Quantum simulators have the potential to revolutionize the way simulations are performed by - accessing system sizes that are untractable in classical machines. As a result, they will become a suite of powerful and precise instruments enabling the investigation of relevant phenomena in the dynamics of complex quantum systems, such as quantum - transport and energy transfer, as well as implementing quantum improved computation - tasks hard to simulate classically. QUCHIP aims at implementing quantum simulation on integrated photonic processors. Photons present unique advantages deriving - from their mobility and the immunity to decoherence: these two features make them substantially different from any other quantum system. Moreover integrated quantum photonics capitalizes on the multi-billion dollar investment already placed into - photonics development and commercialization. QUCHIP will exploit these advantages to implement quantum walk experiments in which several photons propagate over complex circuit architectures “jumping” between different waveguides. This platform - represents the most resource-efficient quantum computation scheme to date: Boson Sampling. Recent computational theory findings have shown exceptional potential for this scheme to achieve the quantum supremacy regime in which quantum systems surpass - classical ones. QUCHIP will develop new photonic technologies, ranging from on-chip sources of single photons to complex waveguide architectures and on-chip detectors. We will explore the dynamics of noisy quantum networks and develop practical - schemes to demonstrate key structural and functional elements of the network dynamics. The benefits range from insights into the dynamics of complex systems to a dramatic push forward for the realization of an experimental device whose output cannot - be formally calculated by classical means. - - 2018-02-28, ongoing project - - - 2015-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.2."> - - - FETPROACT-3-2014 - Quantum simulation - - - RIA - Research and Innovation action - - - Italy - - - QUCHIP - - - H2020-FETPROACT-2014 - - - 641039 - - - - - UNIVERSITEIT VAN AMSTERDAM - - - EUR 177 598,80 - - - Oscillatory long-Range Coherence in Attention - - - EUR 177 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Attention -the ability to focus selectively on task relevant information and resist distraction- plays a critical role in many everyday life situations, such as in school or while driving. With an almost constant stream of - information reaching us through smart phones and computers, our world becomes increasingly distracting, requiring enhanced attentional capabilities. This calls for new approaches to improve attention, also benefiting patients populations suffering - from attention deficits. Is it possible to safely improve attention without medication? And how does the brain actually guides attention and resist distractions? The proposed research aims to answer these questions by combining a novel brain - stimulation technique, transcranial alternating current stimulation (tACS) with state of the art neuroimaging methods. It will specifically test the intriguing hypothesis that attention can be enhanced by synchronizing rhythmic activity between two - brain regions previously shown to be involved in attention. In the first study I will assess the effects of stimulation on attention performance, while simultaneously measuring neural activity using electroencephalogram (EEG). This will allow me to - determine to what extent tACS can improve attention and investigate the causal role of neural oscillations in attention. In the second study, tACS will be combined with functional magnetic resonance imaging (fMRI) allowing to bridge the literature on - neural oscillations (derived from EEG research) and attention networks (derived from fMRI research). Specifically, it will provide novel insights into the exact neural network subserving oscillatory activity associated with attention. Taken together, - this project will not only investigate an innovative way to improve attention, with important implication for future clinical studies, but will also have a major contribution to cognitive neuroscience theories of attention. - - 2018-07-31, ongoing project - - - 2016-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - ORCA - - - H2020-MSCA-IF-2015 - - - 702402 - - - - - UNIVERSITEIT GENT - TELECOMMUNICATION SYSTEMS INSTITUTE - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - POLITECNICO DI MILANO - UNIVERSITEIT VAN AMSTERDAM - RUHR-UNIVERSITAET BOCHUM - MAXELER TECHNOLOGIES LIMITED - SYNELIXIS LYSEIS PLIROFORIKIS AUTOMATISMOU & TILEPIKOINONION MONOPROSOPI EPE - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 3 989 930,50 - - - Exploiting eXascale Technology with Reconfigurable Architectures - - - EUR 3 989 931,25 - - - Belgium - Greece - United Kingdom - Italy - Netherlands - Germany - United Kingdom - Greece - United Kingdom - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - To handle the stringent performance requirements of future exascale High Performance Computing (HPC) applications, HPC systems need ultra-efficient heterogeneous compute nodes. To reduce power and increase performance, such - compute nodes will require reconfiguration as an intrinsic feature, so that specific HPC application features can be optimally accelerated at all times, even if they regularly change over time. - - - 2018-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.2."> - - - FETHPC-1-2014 - HPC Core Technologies, Programming Environments and Algorithms for Extreme Parallelism and Extreme Data Applications - - - RIA - Research and Innovation action - - - Belgium - - - EXTRA - - - H2020-FETHPC-2014 - - - 671653 - - - - - JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN - JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN - - - EUR 1 499 693,71 - - - Non-coding RNA in Vascular Ageing - - - EUR 1 499 693,71 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Life expectancy in the European Union is rising and the prevalence of age-induced cardiovascular disease increases concomitantly. Endothelial dysfunction is a hallmark of aging in the vasculature and is the underlying cause of - many cardiovascular disorders, like hypertension, acute myocardial infarction and stroke. This proposal aims to better understand the molecular mechanisms behind aging that lead to endothelial dysfunction. - - 2020-03-31, ongoing project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - NOVA - - - ERC-2014-STG - - - 638178 - - - - - UNIVERSITAET ULM - UNIVERSITAET STUTTGART - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - JOHANNES GUTENBERG-UNIVERSITAT MAINZ - AARHUS UNIVERSITET - THE UNIVERSITY OF NOTTINGHAM - UNIVERSITY OF DURHAM - Eidgenössische Technische Hochschule Zürich - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - CENTRE INTERNATIONAL DE RECHERCHE AUX FRONTIERES DE LA CHIMIE - CONSIGLIO NAZIONALE DELLE RICERCHE - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - UNIVERSITEIT VAN AMSTERDAM - UNIVERSITAET INNSBRUCK - TECHNISCHE UNIVERSITEIT EINDHOVEN - UNIVERSITAET KASSEL - - - EUR 4 383 000 - - - Rydberg Quantum Simulators - - - EUR 4 695 000 - - - Germany - Germany - France - Germany - Denmark - United Kingdom - United Kingdom - Switzerland - Germany - France - Italy - Germany - Netherlands - Austria - Netherlands - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Quantum Simulators provide new levels of understanding of equilibrium and out-of-equilibrium properties of many-body quantum systems, one of the most challenging problems in physics. The main objective of the RYSQ project is - to use Rydberg atoms for quantum simulations, because their outstanding versatility will allow us to perform a great variety of useful quantum simulations, by exploiting different aspects of the same experimental and theoretical tools. By - implementing not only one but a whole family of Rydberg Quantum Simulators, the project will address both the coherent and incoherent dissipative dynamics of many-body quantum systems, with potential applications in the understanding and design of - artificial light harvesting systems, large quantum systems with controlled decoherence, and novel materials. This will be achieved by building upon a novel generic approach to quantum simulation, where Rydberg atoms allow both digital (gate) and - analog (interaction) simulations. - - - 2018-02-28, ongoing project - - - 2015-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.2."> - - - FETPROACT-3-2014 - Quantum simulation - - - RIA - Research and Innovation action - - - Germany - - - RYSQ - - - H2020-FETPROACT-2014 - - - 640378 - - - - - CHALMERS TEKNISKA HOEGSKOLA AB - UNIVERSITAET STUTTGART - TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY - INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE - UNIVERSITAET AUGSBURG - Eidgenössische Technische Hochschule Zürich - UNIVERSITEIT GENT - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - THE UNIVERSITY OF EDINBURGH - RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN - THE UNIVERSITY OF MANCHESTER - ETA SCALE AB - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - FUNDACION UNIVERSITARIA SAN ANTONIO DE CARTAGENA - NANE RAZVAN - - - EUR 1 489 980,75 - - - EuroLab-4-HPC: Foundations of a European Research Center of Excellence in High Performance Computing Systems - - - EUR 1 489 981,25 - - - Sweden - Germany - Israel - France - Germany - Switzerland - Belgium - Switzerland - Spain - Greece - United Kingdom - Germany - United Kingdom - Sweden - Germany - Spain - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Europe has built momentum in becoming a leader in large parts of the HPC ecosystem. It has brought together technical and business stakeholders from application developers via system software to exascale systems. Despite such - gains, excellence in high performance computing systems is often fragmented and opportunities for synergy missed. To compete internationally, Europe must bring together the best research groups to tackle the longterm challenges for HPC. These - typically cut across layers, e.g., performance, energy efficiency and dependability, so excellence in research must target all the layers in the system stack. - - - 2017-08-31, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.2."> - - - FETHPC-2-2014 - HPC Ecosystem Development - - - CSA - Coordination and support action - - - Sweden - - - EuroLab-4-HPC - - - H2020-FETHPC-2014 - - - 671610 - - - - - UNIVERSITAET KASSEL - UNIVERSITAET KASSEL - - - EUR 1 500 000 - - - Human Cooperation to Protect the Global Commons - - - EUR 1 500 000 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The objectives of this research are to reveal the nature of large-scale human cooperation and to develop strategies for the protection of our global environment. Human activities are now the major driver of change in the - biosphere, including the climate, the water cycle, and the distribution of species and biodiversity – with adverse effects that range from the local to the global scale. Since there is no world government that can enforce the protection of the global - commons we have to rely on voluntary cooperation by sovereign actors. Previous findings from various disciplines have taught us important lessons about the nature of human cooperation. However, these literatures have almost exclusively focused on - local or regional cooperation problems and their findings cannot be readily transferred to the international level. The research proposed here will fill this crucial gap. The methodological approach is genuinely interdisciplinary. In particular, the - project will use and combine theoretical, experimental, evolutionary, and empirical methods. The interdisciplinary research team will start by analyzing case studies of international cooperation (or lack thereof). In an iterative process, the - case-specific results will be explored in a rigorous context-free analysis using theoretical modeling, experiments, and simulations. With this, the project will: systematically analyze human cooperation from the local to the global scale and the - differences between those scales; investigate which institutional arrangements enhance or prevent cooperative behavior at the global level; investigate whether individuals and groups are able to choose the right institutions and which factors - determine their choice; synthesize the results to derive theoretical and practical insights about human cooperation and develop effective strategies for the management of the global commons; bring forward the integration of concepts and methods - across disciplines for the study of human cooperation. - - 2020-07-31, ongoing project - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - HUCO - - - ERC-2014-STG - - - 636746 - - - - - KING'S COLLEGE LONDON - KING'S COLLEGE LONDON - - - EUR 1 999 776 - - - REACH: Risk, Resilience, Ethnicity and AdolesCent Mental Health - - - EUR 1 999 776 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The overarching aim of REACH is to examine groundbreaking questions on the developmental origins of psychosis in migrant and minority ethnic populations using a highly innovative accelerated cohort study of adolescents, to be - conducted in south London (UK). It has been known for over 50 years that the incidence of psychotic disorders is high in many migrant and minority ethnic groups across many countries. Our seminal study (AESOP) on this, for example, found that - incidence rates were 3 to 6 times higher in black Caribbean and black African populations in the UK than in the white British. There have, however, been no public health initiatives specifically designed to tackle this problem – this is a public - health tragedy. In part this inaction is due to a limited understanding of why rates of disorder are elevated. This points to an urgent need for research that can shed light on why the incidence of psychosis is so high in some populations and, more - importantly, provide information on how and when to intervene to reduce risk. In seeking to do this, REACH will break new ground. To achieve these aims, REACH will use highly innovative methods to recruit, assess and follow at one and two years 3 - overlapping school-based cohorts of adolescents aged 11-12, 12-13 and 13-14 years (total sample, 2,760; 552 of whom will be assessed more intensively). Collection of data on a) psychotic and other experiences of emotional distress, b) - socio-environmental risk and, uniquely, protective factors, and c) psychological and biological (HPA axis related) mechanisms, will enable REACH to examine cutting edge questions about the developmental origins of psychosis. REACH is an ambitious - study that, critically, seeks to explain (not just document) ethnic differences and in doing so provide concrete proposals for prevention strategies and interventions to reduce risk of psychosis and other poor mental health outcomes during - adolescence, a key developmental stage, in diverse ethnic groups. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - REACH - - - ERC-2014-CoG - - - 648837 - - - - - UNIVERSITEIT VAN AMSTERDAM - UNIVERSITEIT VAN AMSTERDAM - - - EUR 1 497 764 - - - Corporate Network Governance: Power, Ownership and Control in Contemporary Global Capitalism - - - EUR 1 497 764 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The character of global business networks has long fascinated but continues to divide scholars of global markets and governance. A well-established perspective looks at the changes in global networks and sees an emerging - cohesive transnational capitalist class. However, a rival line of inquiry sees the rise of competing corporate elites. Scholars also disagree on the origins of emergent patterns of corporate networks. Do they reflect institutional preferences of - corporate and political elites? Or are they unintended by-products of corporate conduct? Third, there are fundamental differences of opinion on how patterns of global corporate ownership relate to actual power in the governance of such networks. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - CORPNET - - - ERC-2014-STG - - - 638946 - - - - - UNIVERSITEIT VAN AMSTERDAM - UNIVERSITEIT VAN AMSTERDAM - - - EUR 2 000 000 - - - Causes and consequences of change in public opinion about Europe - - - EUR 2 000 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Causes and consequences of change in public opinion about Europe - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - EUROPINIONS - - - ERC-2014-CoG - - - 647316 - - - - - UNIVERSITEIT VAN AMSTERDAM - - - EUR 177 598,80 - - - Trauma Studies in the Digital Age: The Impact of Social Media on Trauma Processing in Life Narratives and in Trauma Literature: the Case of Hungary - - - EUR 177 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - The aim of the TRAPRODIG project is to analyse cultural and literary trauma processing in the framework of digital memory studies, particularly in relation to the similarities and differences of collective trauma processing - and trauma literature in modern democracies and dictatorships; with a special trans-cultural focus on the case of Hungary as a post-socialist country with unresolved twentieth century collective traumas and on life narratives of Hungarian migrants in - Europe, especially in the United Kingdom. - - 2018-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - TRAPRODIG - - - H2020-MSCA-IF-2015 - - - 701883 - - - - - UNIVERSITEIT UTRECHT - UNIVERSITEIT UTRECHT - UNIVERSITEIT VAN AMSTERDAM - - - EUR 1 907 944 - - - Technique in the Arts. Concepts, Practices, Expertise (1500-1950) - - - EUR 1 907 944 - - - Netherlands - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The transmission of ‘technique’ in art has been a conspicuous ‘black box’ resisting analysis. The tools of the humanities used to study the transmission of ideas and concepts are insufficient when it comes to understanding the - transmission of something as non-propositional and non-verbal as ‘technique’. The insights of the neurosciences in, for example, the acquisition and transmission of drawing skills are not yet sufficiently advanced to be historically restrictive. - However, only in the most recent years, the history of science and technology has turned to how-to instructions as given in recipes. This project proposes to undertake the experimental reconstruction of historical recipes to finally open the black - box of the transmission of technique in the visual and decorative arts. Considering ‘technique’ as a textual, material and social practice, this project will write a long-term history of the theory and practice of the study of ‘technique’ in the - visual and decorative arts between 1500 and 1950. The three central research questions here are: (1) what is technique in the visual and decorative arts, (2) how is technique transmitted and studied, and (3) who is considered expert in technique, and - why? This project will make a breakthrough in our understanding of the transmission of technique in the arts by integrating methodologies typical for the humanities and historical disciplines with laboratory work. Also, by providing a history of - technique in the arts, this project lays the historical foundations of the epistemologies of conservation, restoration and technical art history precisely at a moment of greatest urgency. The connection between the history of science and technology - and the expertise in conservation, restoration and technical art history (in the Ateliergebouw in Amsterdam) this project envisions builds the intellectual infrastructure of a new field of interdisciplinary research, unique in Europe. - - 2020-08-31, ongoing project | - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - ARTECHNE - - - ERC-2014-CoG - - - 648718 - - - - - UNIVERSITY OF BRISTOL - - - EUR 183 454,80 - - - Formal Truth in Epistemology - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Understanding the notions of truth and knowledge has been at the root of the philosophical enterprise since the very beginning. It turns out that these notions are intimately related and that understanding truth requires - understanding knowledge and vice versa. Constitutive questions concerning these notions, such as “Are there truths that cannot be known?” can only be understood, let alone answered, if we have a grasp of both notions. Epistemology, conceived as the - study of human knowledge, should therefore simultaneously investigate the notion of truth. Surprisingly, very little research has been conducted from this perspective. Rather research on truth and research on knowledge has been mostly conducted - independently. This project will approach the traditional epistemological question of the definition of knowledge from this integrated perspective, and attempt to bridge a gap between current research in epistemology and research on theories of - truth. - - - 2018-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - TREPISTEME - - - H2020-MSCA-IF-2015 - - - 703539 - - - - - UNIVERSITEIT VAN AMSTERDAM - - - EUR 165 598,80 - - - The unique dioxygenases of phytophagous spider mites: new enzyme players in plant-herbivore interactions? - - - EUR 165 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Detoxification of poisonous xenobiotics in animals is typically performed by multi-gene enzyme families. Within arthropods, only insect genomes have been studied in detail where these families are well characterized. I - recently uncovered a new enzyme family in the genome of a non-insect arthropod, the extremely polyphagous plant-feeding mite Tetranychus urticae and showed that this proliferated family was acquired via horizontal gene transfer from a fungal donor. - The family codes for intradiol ring cleaving dioxygenases which cleave a particular set of aromatic structures, commonly found in pesticides and plant metabolites. Here, I propose to functionally characterize this exciting new gene family and to - elucidate its role in xenobiotic detoxification, with a focus on plant secondary metabolites. First, to create a general picture, I will map the in situ expression of dioxygenases and time their responses to plant-derived secondary defense - metabolites. Second, guided by preliminary results, I plan to study how these new herbivore enzymes counteract polyphenol oxidases, well-known plant defense enzymes that act against herbivores and target the same class of substrates. State-of-the-art - plant transformation experiments will be performed in order to meticulously dissect their counterplay. Finally, by means of an unbiased multi-layered strategy, I will functionally characterize these new dioxygenases. Dioxygenases will be introduced - into biological systems by functional expression in E. coli or insect cells, and by genetically transforming Drosophila. Cutting-edge differential metabolomics will identify the substrates and reaction products. By means of this project, I expect to - unravel the selective advantage of this new family for phytophagous mites and open up avenues to exciting biotechnological applications which I expect to extend well beyond agriculture. - - 2017-08-31, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - DOGMITE - - - H2020-MSCA-IF-2014 - - - 658795 - - - - - UNIVERSITY OF BRISTOL - - - EUR 183 454,80 - - - Probabilistic Assessment of Reduction and Transfer of Natural Earthquake Risk - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Seismic risk management in fast-growing populated seismic areas is a challenge for governments and communities in case of catastrophic events. Seismic resilience options are considered to mitigate risk, by either reducing the - risk through vibration-control designs of risky assets, or by transferring the risk into the capital markets, through disaster financing options or (re)insurers. Both strategies require a good understanding of the seismic risk, which can be achieved - only through thorough ground-motion uncertainty quantification and propagation to structural response, and accurate estimates of damage, cost and downtime estimates of the affected assets. - - 2018-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - PARTNER - - - H2020-MSCA-IF-2015 - - - 704679 - - - - - KING'S COLLEGE LONDON - - - EUR 195 454,80 - - - Re-Exploring the Logic of Gandhian Violence: Gandhi and his Followers in the Quit India Movement, Bengal 1942-45 - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - 'Re-Exploring the Logic of Gandhian Violence: Gandhi and his Followers in the Quit India Movement, Bengal 1942-45 - - 2018-09-12, ongoing project - - - 2016-09-13 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - Gandhian Politics - - - H2020-MSCA-IF-2015 - - - 702950 - - - - - KING'S COLLEGE LONDON - - - EUR 183 454,80 - - - Engineering the 3D Niche to enHANCE functionality of hepatocytes derived from human iPSCs - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Induced pluripotent stem cell derived hepatocytes (i-Heps) afford us the exciting possibility of redressing the growing shortage in liver transplantation tissue and heralding in a new era of patient specific drug and disease - modelling. Clinical applications are restricted by their poor functionality in comparison to the gold standard – freshly isolated primary hepatocytes. Emerging evidence suggests the three dimensional environment surrounding a cell (the niche) - critically influences cellular function. The objective of ENHANCE is to identify relevant factors from the extracellular niche which promote i-Hep function in 3D and the mechanisms by which they achieve this. This new knowledge will be used to - generate functionally optimized i-Hep constructs suitable for clinical transplantation, with proof of concept studies being performed in rodent models of liver failure. This European Fellowship at Kings College London will provide the researcher with - advanced training in iPSC technology, i-Hep generation, 2D niche component screening, 3D cell engineering and animal transplantation. A secondment to SME DefiniGEN Ltd will evaluate the feasibility of transfer to a commercial i-Hep production - platform as a critical step towards clinical trials. - - 2018-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ENHANCE - - - H2020-MSCA-IF-2015 - - - 705607 - - - - - KING'S COLLEGE LONDON - - - EUR 183 454,80 - - - GENOMIC AND METABOLIC REGULATION OF METASTATIC CANCER STEM CELLS - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The major causes of cancer deaths are relapse and resistance to current therapies associated with the presence of cancer stem cells (CSCs) and metastatic growth in distant organs. CSCs have the ability to self-renew and - differentiate in non-CSCs. In breast cancer, acquisition of stemness properties has been closely related to epithelial-mesenchymal transition (EMT), a key process in cancer invasion and metastasis triggered via Rho-ROCK mediated actomyosin - contractility. Interestingly, in melanoma, transition from elongated-mesenchymal to amoeboid mode of movement (MAT) driven by Rho-ROCK signalling has been associated with increased stemness. Furthermore, preliminary data from host lab shows that - actomyosin cytoskeletal regulates glutamine metabolism in both melanoma and breast cancer cells. Metabolic cues participate in stem cell self-renewal regulation, suggesting that, in very contractile cells, the regulation of EMT, metastatic spread and - tumour initiation might be functionally linked to stemness via metabolic clues. Nevertheless, how very contractile cells regulate genes involved in all these processes remains unexplored. As increasing contractility via EMT in carcinoma cells or via - MAT in melanoma cells correlates with increasing stemness, we hypothesize a molecular link between the pathways regulating both migration and stemness abilities, which will be maintained across tumour types (from carcinoma to melanoma). The main goal - of this proposal is to understand how tumour cells can acquire stem cell traits to successfully metastasize and how this can be regulated by the actomyosin cytoskeletal by using an interdisciplinary approach that combines state-of-the-art techniques - in molecular and cellular biology, biochemistry, in vivo imaging and animal models. This will allow to identify key important genes regulating both stemness traits and metastatic spread with the ultimate goal of unravelling novel drug targets and - prognostic markers of distant relapse. - - 2018-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - GENMETASTEM - - - H2020-MSCA-IF-2014 - - - 659022 - - - - - UNIVERSITEIT VAN AMSTERDAM - - - EUR 177 598,80 - - - Radical Contextualism and the Science of Meaning - - - EUR 177 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - The project investigates the impact that ‘radical contextualism’ (RC) has upon certain foundational issues in the philosophy of language, formal semantics, and philosophy of science. What motivates RC is the idea that our - interpretation of a word, and what we refer to by using it, might be very different on different occasions of use. This suggests that our ability to interpret words, or to understand what they mean, depends in part on our being familiar with certain - features of the occasions on which words are actually put to use. However, since communicative occasions are not systematically tractable, this seems to render systematic theories of meaning impossible. My chief objective is to think of a way out of - this difficulty whilst taking the intuition behind RC seriously. - - - 2017-08-31, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - Netherlands - - - RContext - - - H2020-MSCA-IF-2014 - - - 656273 - - - - - UNIVERSITY OF BRISTOL - - - EUR 183 454,80 - - - Multicompartmental Designs For Protocells - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Protocells are artificial mimics of cellular systems exhibiting some of the quintessential characteristics of living systems such as compartmentalization, replication and selective exchange of chemical species with the - environment. Apart from enabling better understanding about the origin of life, protocells can also be perceived as micromachines which can be programmed to perform functions such as clinical diagnosis, drug delivery, remote sensing, environment - detoxification, etc. The range of applications for protocells can be broadened by increasing their structural complexity which would enable complex functions. However, to date the structural complexity of protocellular models has been minimal. - Eukaryotic cells are model systems for complexity with compartmentalization into membrane bound organelles interacting through selective exchange of metabolites resulting in complex chemical networks which make possible smart functions such as - feedback regulation and homeostasis. No parallel of this hierarchical organization exists in protocell literature. The aim of this proposal is to address this issue by design and construction of multicompartmental protocell models capable of complex - functions such as self-regulation, locomotion and light harvesting. The interaction between the various compartments will be enabled by constructing gates across their membranes using stimuli responsive polymers to allow compartments to activate - pathways which can affect the function or metabolite level of another compartment, leading to self-regulation of function or metabolite levels in the protocell. It is in this regard that the previous expertise of the applicant (Dr. Pavan Kumar) in - constructing gates to control the transport in nanochannels will be applied to the multi-disciplinary and cutting edge field of protocells in which the hosting group at the University of Bristol (under the leadership of Prof.Stephen Mann FRS) has - made tremendous progress in the last few years. - - 2018-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - Protoeukaryotes - - - H2020-MSCA-IF-2015 - - - 705165 - - - - - UNIVERSITY OF PORTSMOUTH HIGHER EDUCATION CORPORATION - UNIVERSITY OF PORTSMOUTH HIGHER EDUCATION CORPORATION - - - EUR 1 701 132,50 - - - Cosmological Tests of Gravity - - - EUR 1 701 132,50 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Einstein’s theory of General Relativity (GR) is tested accurately within the local universe i.e., the solar system, but this leaves open the possibility that it is not a good description at the largest scales in the Universe. - The standard model of cosmology assumes GR as a theory to describe gravity on all scales. In 1998, astronomers made a surprising discovery that the expansion of the Universe is accelerating, not slowing down. This late-time acceleration of the - Universe has become the most challenging problem in theoretical physics. Within the framework of GR, the acceleration would originate from an unknown “dark energy.” Alternatively, it could be that there is no dark energy and GR itself is in error on - cosmological scales. The standard model of cosmology is based on a huge extrapolation of our limited knowledge of gravity. This discovery of the late time acceleration of the Universe may require us to revise the theory of gravity and the standard - model of cosmology based on GR. - - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - CosTesGrav - - - ERC-2014-CoG - - - 646702 - - - - - KING'S COLLEGE LONDON - - - EUR 183 454,80 - - - Tracing the global fertility chain- A new political economy of outsourced reproduction - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - In a new kind of post-Fordist niche, called the reproductive bio-economy, organised around the “flow” of reproductive substances and organs, such as egg cells, embryos and wombs, women are increasingly commercialising their - bodies by working as oocyte vendors, surrogate mothers or tissue providers. There is fundamental disagreement among scholars and policy makers on how the reproductive bio-economy should be organised. Market critics propose a gift economy based on - altruistic donations and informed consent, while market proponents encourage the commercialisation of reproductive tissues and the remuneration of tissue providers. This research addresses and moves beyond the conflicting terms (gift v. commodity, - reproduction v. production, labour v. donation) in which the debate has been framed. It empirically investigates how (bio-)value is created and governed in one particular strand of the “actually existing” reproductive bio-economy, i.e. the global - fertility industry, by exploring the intricate ways in which reproductive tissues and labour move in and out of a commodity state as they move through different regimes of governance. By ethnographically mapping the shifting regimes of labour and - property in one specific fertility chain that is becoming increasingly popular, i.e. between Israel/Palestine, South Africa (oocyte vending) and Nepal (surrogacy), the volatile boundaries between gift and commodity, value and waste, labour and - donation, property and entitlement will be unpacked. This will be done in an attempt to discern “hidden strategies of resistance” of female reproductive workers in the Global South, and propose alternative and more emancipatory ways of configuring - the governance of the reproductive bio-economy. - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - globalfertilitychain - - - H2020-MSCA-IF-2015 - - - 704261 - - - - - UNIVERSITY OF BRISTOL - - - EUR 183 454,80 - - - Quantum Unique Ergodicity and Random Waves on Graphs - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The proposal aims to address two important conjectures of Quantum Chaos, Quantum Unique Ergodicity and the Random Wave hypothesis, via the analysis of eigenfunctions of the Laplacian on discrete graphs. It will provide a - better understanding of two difficult problems of mathematical physics through an original approach, while developing spectral theory on graphs. The latter has a strong potential of applications in the study of networks, whose understanding is of - great importance in the modern world. The expertise of the experienced researcher on analysis on graphs will be ideally complemented by the quantum chaos and ergodic theory specialists of the University of Bristol, to ensure the success of this - project. - - 2018-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - QUERWG - - - H2020-MSCA-IF-2015 - - - 703162 - - - - - UNIVERSITEIT VAN AMSTERDAM - - - EUR 177 598,80 - - - The impact of recent retrotransposon invasions on the evolution of human neural gene expression - - - EUR 177 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Throughout evolution, primate genomes have been under attack by different classes of retrotransposons, retrovirus-derived mobile DNA elements. As a result, an astonishing ~50% of the human genome is derived from many types of - retrotransposons. I previously showed that primate-specific retrotransposon invasions are restricted by primate-specific KRAB zinc finger proteins. These findings suggest that through recruitment to thousands of new genomic locations, KRAB zinc - finger proteins have become intimately integrated into pre-existing gene regulatory pathways. Retrotransposons are an important source for evolutionary novelties, but the impact of thousands of human-specific retrotransposon-KZNF regulatory modules - on the evolution of human gene expression patterns is unknown. There is increasing evidence that retrotransposons become reactivated during neural differentiation, suggesting that neuronal gene-regulatory networks may be extra sensitive to - retrotransposon insertions. Furthermore, new retrotransposon insertions may hold clues to the mechanism of human disease: Even when retrotransposons are efficiently silenced in health, they may become aberrantly activated by changes in DNA - methylation observed in neurological diseases and cancer. Using a previously established human and non-human primate stem cell cortical neuron differentiation assay, I will identify, validate and functionally test neurodevelopmental genes that have - come under the control of retrotransposons. This will address the impact of recent waves of retrotransposon insertions on the evolution of human neural gene expression patterns and opens up the exploration of how new retrotransposon insertions may be - correlated to human neurological disorders. The Marie Skłodowska-Curie individual fellowship will provide the opportunity to establish my research group in Europe and re-integrate in Dutch and EU networks, as well as allow me to achieve my - professional development training goals. - - 2017-05-31, closed project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Netherlands - - - Evolutionary Neurogenomics - - - H2020-MSCA-IF-2014 - - - 659193 - - - - - UNIVERSITY OF BRISTOL - - - EUR 183 454,80 - - - Communication through Polarity-Switchable Foldamers - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - We propose to develop a new, artificial but bio-inspired mechanism for communicating information in chemical systems, by using the potential for hydrogen-bond reorganisation of novel dynamic 'refoldable foldamers', combined - with biology's information storage mechanisms. Biological information is encoded in DNA or RNA by two dimensional arrangements of hydrogen bond donors and acceptors in nucleotide sequences: we will innovate nanoscale communication devices that read - information encoded in this way, and translate it directly into a chemical feature (catalytic activity, ligand-binding ability) at a site remote from the source of information. Conceptually we shall telescope the biological processes of transcription - and translation into a single conformational event in a single molecule. - - 2018-04-03, ongoing project - - - 2016-04-04 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - REFOLDAMER - - - H2020-MSCA-IF-2015 - - - 701318 - - - - - HUMBOLDT-UNIVERSITAET ZU BERLIN - - - EUR 159 460,80 - - - The implementation of the EU employment policies in Germany, Italy and Denmark - - - EUR 159 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - Unemployment is one of the major challenges that the world economy is facing at present. The European Union (EU) is trying to cope with this problem by promoting the flexicurity strategy (Europe 2020: COM(2010) 2020 final). - This strategy aims to conciliate the flexibility requested by companies and the social and employment security needed by workers (COM(2007) 359 final). One of its main aspects concerns the relevant role recognized to active and passive labour market - policies (active and passive LMPs). At the same time, the flexicurity concept is vague and ambiguous: this aspect brings difficulties in its implementation, and can have negative implications on the level of protection of unemployed people. The - research project aims to analyse the legal implementation/adaptation (i./a.) of the flexicurity strategy – with regard to active and passive LMPs – in three member states: Germany, Italy and Denmark, that are representative of three different kinds - of social security systems in EU, (Continental, Mediterranean and Nordic systems). - - - 2017-05-31, closed project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - EUP - - - H2020-MSCA-IF-2014 - - - 654925 - - - - - UNIVERSITY OF BRISTOL - - - EUR 183 454,80 - - - Efficient Spin-Photon Coupling in the Solid-State - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The efficient coupling of a single electron spin to a single photon would represent a major milestone in our technological progress, and would lead to revolutionary advancements in communication and computation technologies - exploiting quantum mechanical phenomena. Recently nano-scale `domes' of semiconductor known as quantum dots have emerged as the leading platform upon which this goal can be achieved; they can host localised electrons, and around them micro `pillars' - can be grown which serve to channel photon emission. The catch, however, is that these are solid-state systems, and a quantum dot inevitably interacts with a large perturbing environment. The central question motivating this research is: - - - 2018-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ESPCSS - - - H2020-MSCA-IF-2015 - - - 703193 - - - - - UNIVERSITY OF BRISTOL - - - EUR 183 454,80 - - - Optimizing for Happiness in Personal Finance - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - In this project, we will (1) investigate the ability to use the log of emotional states captured with wearable trackers for improving affective forecasting abilities of people, (2) build a tool for managing personal finance - that integrates prediction analytics, and (3) evaluate if accurate expectations about purchases increase happiness of individuals. - - - 2017-09-29, closed project - - - 2015-09-30 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - OHPF - - - H2020-MSCA-IF-2014 - - - 655723 - - - - - THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS - - - EUR 195 454,80 - - - Brain growth under social pressure: mathematical modelling of brain growth when individuals face social challenges - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Growing and maintaining a large brain entails substantial energetic costs. A large brain can evolve if costs are compensated by benefits from associated cognitive abilities. Leading hypotheses for brain evolution consider - benefits arising from the solution of ecological and social problems. However, progress has been hindered by the unavailability of mathematical theory generating testable hypotheses from known causes. - - 2018-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SocialBrain - - - H2020-MSCA-IF-2015 - - - 701464 - - - - - FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG - - - EUR 171 460,80 - - - CO2 LOSS FROM STREAMS IN EUROPEAN KARST SYSTEMS - - - EUR 171 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - The proposed study aims to elucidate novel aspects about carbon cycling within European karstic watersheds, via stable isotope and flux determinations of dissolved and particulate carbon. Rivers situated in karst bedrock are - thought to emit significant quantities of CO2, and due to their large combined surface areas and the abundance of karst terrains worldwide, these features play a crucial but as yet unclear role in the global carbon cycle. The projected work will - address this lack of information through the innovative use of stable isotopes, together with the modeling of CO2 evasion and simultaneous flux determinations of dissolved and particulate riverine carbon. The rivers of study are located in Bavaria, - Germany, and are tributaries of the Rhine River in a prominent karst terrain of the Franconian Alb. For comparison, a watershed situated in silicate bedrock, the Uhlířská Basin in the Czech Republic, will also be investigated. The research findings - will reduce uncertainties in the global carbon budget, and clarify linkages between carbon cycling and climate change. This is an important topic for policymakers in Europe, given the political and economic impacts of global warming. - - 2019-01-31, ongoing project - - - 2017-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - EURO-KARST - - - H2020-MSCA-IF-2015 - - - 706088 - - - - - KING'S COLLEGE LONDON - - - EUR 183 454,80 - - - The War on Music. Heritage, Islam and Peacekeeping in relation to the Islamist attacks in Mali - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - This project offers a critical approach to the recent phenomenon of the Islamist attacks on cultural heritage. Its objectives are to analyze 1) the performative and musical dimensions of Islamic identity during conflicts and - 2) the global protection policies of the so-called “intangible heritage”. In addition, it aims at 3) building a new paradigm for post-conflict reconstruction and peacekeeping in collaboration with King’s College London experts and with international - organizations (Secondment). The research develops around a central case-study: the attacks on music (formal interdictions, threats to musicians, destruction of musical instruments) that occurred during the Northern Mali occupation by armed groups - claiming to be Islamists in 2012, and the intangible heritage protection and reconstruction programs implemented by the Malian Government, UNESCO, UN peace force and the European Union. - - - 2018-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - WARMUSIC - - - H2020-MSCA-IF-2015 - - - 702725 - - - - - UNIVERSITEIT VAN AMSTERDAM - - - EUR 165 598,80 - - - Democratization through Education? The role of education in strengthening civil agency and voice in Sub-Saharan Africa. (Case study: Uganda) - - - EUR 165 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - EDU-DEM advances our understanding of the role of education in fostering democratization processes in sub-Saharan Africa from the bottom up. Education has been long treated as an area of development programming that is - separate from strengthening civil society formation and democratization processes. We still face several knowledge gaps in existing research on how education increases the agency of the wider civil sphere. This void is striking and it is here where - EDU-DEM makes an innovative contribution to existing debates. In doing so, EDU-DEM will 1) explore the correlations between educational attainment and civil society characteristics and agency; 2) assess how formal and non-formal education systems and - programmes increase the attention to and comprehension of local politics; 3) identify innovative, multi-scalar and context-specific approaches to nurture democratization processes through education. - - 2018-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - EDU-DEM - - - H2020-MSCA-IF-2015 - - - 702880 - - - - - UNIVERSITEIT VAN AMSTERDAM - - - EUR 177 598,80 - - - Deep learning and Bayesian inference for medical imaging - - - EUR 177 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Diseases characteristic for modern western civilization, such as cancer, diabetes or cardiovascular disorders, lead to millions of deaths per year in the European Union. In order to decrease this enormous quantity, medical - imaging should be widely available at early diagnostics and every stage of a therapy. Nowadays, there are various diagnostics techniques including CT, PET, MRI, however, analysis of a medical image is time-consuming and expensive. Development of new - effective automatic tool for medical imaging will appear a new strategy in highly specific control of incidences and disease progression. The aim of the DeeBMED project is to develop powerful automatic medical imaging tool that can cope with main - problems associated with complex images like medical scans: multimodality of data distribution, large number of dimension and small number of examples, small amount of labeled data, multi-source learning, and robustness to transformations. In this - project I will propose a probabilistic framework that combines different deep neural networks (DNN), such as feedforward nets, convolutional nets, Gaussian processes. I will apply DNN to model probabilistic relationships among a medical scan, a - disease label, and hidden variables representing latent factors in data. In the case of a small sample size DNN are prone to overfitting. A possible remedy for that is Bayesian learning, however, it is still challenging how to apply it to DNN. In - this project I will use various approaches: modelling weights uncertainty, Dropout, Bayesian Distillation. As the result I predict identification of the first highly effective medical imaging analysis tool that in the future will be widely used by - radiologists in medical institutes in the whole EU. Novel automation will drastically reduce time and costs of analysis and provide more accessible diagnostics. The project will be carried out at the University of Amsterdam, under the supervision of - Prof. Max Welling. - - 2018-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - DeeBMED - - - H2020-MSCA-IF-2015 - - - 702666 - - - - - KING'S COLLEGE LONDON - KING'S COLLEGE LONDON - - - EUR 149 761 - - - Commercialisation of new miniaturised, automated robots for high throughput training and assessment of dexterity in rats and mice. - - - EUR 149 761 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The invention: We have developed new, cost-effective miniature robots using 3D printers and customised electronics and software. Large numbers of robots can run in parallel unattended for 24 hours a day, 7 days a week. These - robots can be adapted for a variety of applications in industry and research. In this Proof of Concept phase we will begin commercialisation of one of our robots. - - 2017-12-31, closed project - - - 2016-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2015 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - Miniature Robots - - - ERC-2015-PoC - - - 713410 - - - - - KING'S COLLEGE LONDON - - - EUR 269 857,80 - - - Valuing Innovation Options and Policy Flexibility Under Uncertainty - - - EUR 269 857,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - This proposal consists of a two-year outgoing phase (1.5 years at MIT and 6-month secondment at LUISS U. in Italy) and one-year re-integration phase at King’s College London. Following advanced innovation training, it aims to - develop new ideas and frameworks based on real options theory to appraise innovation options and policy flexibility. Besides training/development and dissemination, the proposal will examine two research themes: - - - 2019-07-31, ongoing project - - - 2016-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - INNOVATIONOPTIONS - - - H2020-MSCA-IF-2014 - - - 653413 - - - - - UNIVERSITEIT VAN AMSTERDAM - - - EUR 242 929,80 - - - Duality For Logic On Words - - - EUR 242 929,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Duality For Logic on Words (DFLOW) - - 2018-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Netherlands - - - DFLOW - - - H2020-MSCA-IF-2014 - - - 655941 - - - - - LUNDS UNIVERSITET - LUNDS UNIVERSITET - LAVISION GMBH - - - EUR 150 000 - - - Frequency Recognition Algorithm for Multiple Exposures - - - EUR 150 000 - - - Sweden - Sweden - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - This proof of concept (PoC) project seeks to explore the possibility of commercializing an optical imaging instrument with the unique ability of permitting a single detector to acquire and store several images simultaneously. - This new concept, which is named Frequency Recognition Algorithm for Multiple Exposures (FRAME), employs an "image-coding" strategy, where different exposures are given a unique structural “code”. Thanks to this novel coding approach, the camera - sensor may be exposed to light several times before readout is necessary – a completely new feature within the field of optical imaging. - - - 2017-05-31, closed project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2015 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Sweden - - - FRAME - - - ERC-2015-PoC - - - 692987 - - - - - SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI DI TRIESTE - - - EUR 262 269 - - - Enabling motor control after a spinal cord injury through nanoscaled electrical - - - EUR 262 269 - - - Italy - - - Higher or Secondary Education Establishments - - A spinal cord injury (SCI) has consistent social costs, due to dramatic and disabling consequences and a high incidence on the youngest and most productive population, which can hardly be alleviated by the very few and - controversial therapeutic treatments. In a recent case report, epidural electrostimulation combined with an intense training enabled some highly variable conscious motor control of legs in four motor complete spinal cord injured volunteers. The aim - of understanding the mechanisms behind these improvements can help define more effective pharmacological and electrical stimulating protocols with breakthrough technology to restore functions after a SCI. Experiments will be performed on adult rats, - with an experimental SCI closer to human chronic lesions, on which I will apply the novel enabling protocol with epidural electrostimulation associated with an intense motor training. Outcome will be evaluated with innovative combinations of - electromyographic and kinematic assessments of locomotion and standing posture, in vivo terminal intracellular recordings from lumbar motoneurons and histological examination of spared axons across the lesion. Then, I will employ carbon nanotubes to - devise nanostructured innovative stimulation arrays for a more specific and focussed epidural stimulation to enhance recovery. - - - 2018-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Italy - - - EPI_nanoSTIM - - - H2020-MSCA-IF-2014 - - - 661452 - - - - - UNIVERSITY OF BRISTOL - - - EUR 183 454,80 - - - Generation of prototissues from functional and chemoselective protocells - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Protocells are micro-compartments able to perform or mimic primitive biological functions of real cells. Because of this, they are proposed as stepping-stones towards the understanding of the origin of life on Earth. These - “smart” microcapsules find potential applications in a variety of fields including medicine, pharmacology, energy conversion, and bioengineering. Progress in these fields will be considerably enhanced by gaining control over communication between - protocells, as well as engineering collective functions of protocells. - - 2019-01-31, ongoing project - - - 2017-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - Smart Protocells - - - H2020-MSCA-IF-2015 - - - 701876 - - - - - UNIVERSITEIT VAN AMSTERDAM - - - EUR 174 864,60 - - - Neither Dwarf nor Leviathan: Explaining Territorial and Functional Variation in State Capacity - - - EUR 174 864,60 - - - Netherlands - - - Higher or Secondary Education Establishments - - Citizens live longer, happier lives where states are able to perform their core functions effectively. Even though weak states have received considerable attention from scholars and policy-makers, the concept of state weakness - has remained under-theorized. The shortcomings of current conceptualizations are revealed by mounting empirical evidence that (1) state capacity does not extend homogeneously across national territories and (2) that a state’s capacity to control and - coerce citizens is distinct from its capacity to care for them by providing education and public health. Previous work mostly assumed that the reason why states do not exercise coercion and care throughout the territory is simply their inability to - do so. This perspective, however, cannot explain why states invest more in building capacity in some regions than in others, or why coercive and caring capacity are geographically uneven. To understand this, it is crucial to acknowledge that states - in the developing world can and do invest in building capacity, but are also confronted with the need to ration resources. - - 2018-06-30, ongoing project - - - 2016-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Netherlands - - - STATE CAPACITY - - - H2020-MSCA-IF-2014 - - - 656361 - - - - - KATHOLIEKE UNIVERSITEIT LEUVEN - ECOLE NORMALE SUPERIEURE - RUHR-UNIVERSITAET BOCHUM - ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE - UNIVERSITY OF BRISTOL - CRYPTOEXPERTS SAS - NXP SEMICONDUCTORS BELGIUM NV - TECHNISCHE UNIVERSITEIT EINDHOVEN - - - EUR 3 893 199,84 - - - European Integrated Research Training Network on Advanced Cryptographic Technologies for the Internet of Things and the Cloud - - - EUR 3 893 199,84 - - - Belgium - France - Germany - United Kingdom - United Kingdom - France - Belgium - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - The goal of this ETN is to develop advanced cryptographic techniques for the Internet of Things and the Cloud and to create implementations that offer a high level of security and increased usability, for a wide range of - physical computation platforms. The ITN will equip a group of 15 early stage researchers with a set of interdisciplinary skills combining mathematics, computer science and electrical engineering that will allow them to create advanced cryptographic - solutions that will be available for commercial applications. The 8 partners (including 2 companies) are leading research teams in the area of applied cryptology with a strong track record of collaboration; it is complemented by 6 partner - organisations from industry (including 2 SMEs).The training from the ERSs will be guided by a personal development plan. A central component is training by research supported by an intensive program of workshops, summer schools, seminars, research - visits, and secondments. The training will be complemented with transferable skills that also support the transfer of research to an industrial context. The management structure of the project is built on a pro-active approach with responsibilization - of the fellows. The dissemination and outreach of the project activities target a broad range of stakeholders. The ITN contributes to the ERA by helping to overcome the fragmentation in the area of applied cryptology. The research supports the trust - and security component of the Digital Agenda for Europe and responds to the growing attention of EU policy makers for societal needs related to privacy and cybersecurity. The societal relevance and timeliness of this research has been emphasized by - revelations made by Snowden, that provide clear evidence of mass surveillance by nation states and of serious weaknesses of our current infrastructure. An essential component of a response to these revelations consists a broad deployment of advanced - and innovative cryptographic techniques. - - 2019-02-28, ongoing project - - - 2015-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Belgium - - - ECRYPT-NET - - - H2020-MSCA-ITN-2014 - - - 643161 - - - - - COVENTRY UNIVERSITY - UNIVERSITY OF SOUTHAMPTON - HOCHSCHULE MAGDEBURG-STENDAL - DANMARKS TEKNISKE UNIVERSITET - - - EUR 126 000 - - - Knowledge Exchange for Efficient Passage of Fishes in the Southern Hemisphere - - - EUR 135 000 - - - United Kingdom - United Kingdom - Germany - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The decline of freshwater fish biodiversity is proceeding at an alarming and persistent rate. Given that most fish must undertake some form of migration in order to complete their life-cycle, of particular concern is the - proliferation of hydropower schemes that block migration routes, as well as a variety of other barriers such as weirs and culverts. Several locations in the southern hemisphere are among the major global hotspots of hydropower development. They are - also home to some of the least studied fish communities in the world. Mitigation measures for fish passage have traditionally relied on designs developed for strong swimming fishes of the northern hemisphere. These designs are ineffective for - generally smaller, relatively weak swimming fish, such as those found in temperate regions of the southern hemisphere, but there is very little understanding of the mechanisms involved. This innovative project represents the first systematic attempt - to bring together world-leading practitioners from Europe with biologists, engineers and stakeholders from the southern hemisphere in an effort to exchange knowledge and construct a shared vision for fish passage science and policy. This will be - achieved through systematic review, expert consultation, ecological modelling, training programmes, networking and stakeholder engagement using a novel combination of approaches. The outcomes will include: high quality journal publications; a summer - school; a set of funding bids based on a co-constructed research strategy; and a model predicting fish passage for species of the southern hemisphere. The project’s key performance indicators will include: number of publications on fish passage in - the southern hemisphere; uptake of robust methods in fish passage research; corresponding citations; metrics indicating public awareness (online activity, readership of popular publications, number of people reached in public engagement events); and - policy citations. - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - United Kingdom - - - KEEPFISH - - - H2020-MSCA-RISE-2015 - - - 690857 - - - - - TECHNISCHE UNIVERSITEIT EINDHOVEN - TECHNISCHE UNIVERSITAT DARMSTADT - UNIVERSIDAD CARLOS III DE MADRID - JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN - AALTO-KORKEAKOULUSAATIO - VYSOKE UCENI TECHNICKE V BRNE - POLITECHNIKA WARSZAWSKA - UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA - CESKE VYSOKE UCENI TECHNICKE V PRAZE - UNIVERSITA DEGLI STUDI DELL'AQUILA - UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN - KUNGLIGA TEKNISKA HOEGSKOLAN - DANMARKS TEKNISKE UNIVERSITET - - - EUR 3 785 419,68 - - - Convergence of Electronics and Photonics Technologies for Enabling Terahertz Applications - - - EUR 3 785 419,68 - - - Netherlands - Germany - Spain - Germany - Finland - Czech Republic - Poland - Italy - Czech Republic - Italy - Ireland - Sweden - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Jiri Matas - Tel.: +420 22435721 - Fax: +420 224357385 - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - CELTA: Convergence of Electronics and Photonics Technologies for Enabling Terahertz Applications aims to produce the next generation of researchers who will enable Europe to take a leading role in the multidisciplinary area of - utilizing Terahertz technology for applications involving components and complete systems for sensing, instrumentation, imaging, spectroscopy, and communications. All these technologies are key to tackle important solutions in a large number of focus - areas relevant for the societal challenges identified in the Horizon2020 work programme. To achieve this objective, CELTA is comprised of eleven leading research institutions and assembled a comprehensive research training programme for all the - fifteen early stage researchers (ESRs). CELTA integrates multidisciplinary scientific expertise, complementary skills, and experience working in academia and industry to empower ESRs to work in interdisciplinary teams, integrate their activities, - share expertise, and promote a vision of a converged co-design and common engineering language between electronics and photonics for Terahertz technologies. Therefore, CELTA will introduce the strategy of converged electronics and photonics co-design - in its research program and makes a special effort on establishing a common engineering language in its training program across the electronics, photonics and applications disciplines. We believe this common engineering language and converged - co-design is mandatory to make the next logical step towards efficient and innovation solutions that can reach the market. The detailed compendium of lectures on state-of-the art technology, soft skills and entrepreneurship is accompanied by a - research programme that focuses on THz key technologies. CELTA ESRs will develop three demonstrators: beam steering technology for communication applications, a photonic vector analyser for spectroscopy and materials characterization, and a THz - imager for sensing applications. - - 2020-02-29, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Netherlands - - - CELTA - - - H2020-MSCA-ITN-2015 - - - 675683 - - - - - UNIVERSITA POLITECNICA DELLE MARCHE - STUDIO ASSOCIATO GAIA SNC DEI DOTTORI ANTONIO SARA E MARTINA MILANESE - UBICA SRL - BOGAZICI ULUSLARARASI EGITIM DANISMANLIK MERKEZI VE TICARET LIMITED SIRKETI - DIVERS ALERT NETWORK EUROPE FOUNDATION - STICHTING NHTV INTERNATIONALE HOGESCHOOL BREDA - NOORDWES-UNIVERSITEIT - THE COLLEGE OF EXPLORATION - DIVERS ALERT NETWORK SOUTHERN AFRICA - BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY - - - EUR 1 611 000 - - - Green Bubbles RISE for sustainable diving - - - EUR 1 620 000 - - - Italy - Italy - Italy - Turkey - Malta - Netherlands - South Africa - United States - South Africa - United States - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - Other - Higher or Secondary Education Establishments - - Recreational SCUBA divinga has become a mass leisure activity engaging millions of divers worldwide. The diving industry generates large direct and indirect revenues for coastal communities and Marine Protected Areas (MPAs). - Other benefits linked to diving include the promotion of ocean stewardship, contribution to scientific research, fostering social inclusion and personal development. Yet, diving has also negative impacts, due to damage or disturbance of marine - habitats and organisms and to conflicts with local communities for the access to/use of the same resources, equity issues, or cultural clashes. These aspects clearly relate to the three pillars of sustainability, covering environmental, economic and - social dimensions and can only be addressed by a systemic approach. - - 2018-12-31, ongoing project | - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Italy - - - GreenBubbles - - - H2020-MSCA-RISE-2014 - - - 643712 - - - - - THE UNIVERSITY OF BIRMINGHAM - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - KAROLINSKA INSTITUTET - KING'S COLLEGE LONDON - UNIVERSITE DE LIEGE - GENOME RESEARCH LIMITED - KARLSRUHER INSTITUT FUER TECHNOLOGIE - RIKEN THE INSTITUTE OF PHYSICAL AND CHEMICAL RESEARCH - CONSORCI INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER - BGI EUROPE INSTITUTE FOND - - - EUR 3 758 916,75 - - - Computational and functional annotation of genomic elements during development of the model vertebrate zebrafish - - - EUR 3 758 916,75 - - - United Kingdom - United Kingdom - Germany - Sweden - United Kingdom - Belgium - United Kingdom - Germany - Japan - Spain - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Other - - The recent explosion of next generation sequencing (NGS) data has caught Europe unprepared and led to a critical shortage of computational biology expertise. As NGS methods are expected to become pervasive from basic science - to personalised medicine there is an urgent need for highly skilled young scientists trained in both computational biology and experimental wet lab biology. Our network addresses this important problem of the postgenomic era. We aim to provide - multi-disciplinary skills for a solid foundation in computational biology and developmental genomics. Developmental genomics is central to understanding of ontogeny and many genetic and congenital anomalies, but was outside the scope of the landmark - ENCODE and FANTOM projects. ENCODE highlighted the need for an in vivo vertebrate model that enables high throughput in vivo functional testing of hypotheses generated from genome scale annotation. Zebrafish is an ideal model for extending the scope - of genomics to vertebrate development. We aim to comprehensively annotate functional elements, decipher genomic codes of transcription, as well as coding and non-coding gene function during development and enhance zebrafish as an attractive - developmental, comparative and disease model. The participants include 7 non-academic members (2 of which are beneficiaries), major zebrafish genomics laboratories, eminent computational biologists and world class genomics technology experts active - in FANTOM and ENCODE. The training program involves 15 ESRs, more than 40 intersectoral and interdisciplinary secondments totalling 19 months, 7 training courses and 2 workshops/conferences. The main outcome of this programme is a cohort of - researchers with computational, experimental laboratory and transferable skills ready to further their career in academia, public health and the private sector. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - ZENCODE-ITN - - - H2020-MSCA-ITN-2014 - - - 643062 - - - - - UNIVERSITA CATTOLICA DEL SACRO CUORE - STICHTING VU - BETTER VALUE HEALTHCARE LTD - ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM - UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA - LINKCARE HEALTH SERVICES SL - DEBRECENI EGYETEM - Myriad Genetics Srl - EUROPEAN PUBLIC HEALTH ASSOCIATION - STICHTING VUMC - MOUNT SINAI SCHOOL OF MEDICINE - ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING MCGILL UNIVERSITY - - - EUR 792 000 - - - Personalized PREvention of Chronic DIseases - - - EUR 792 000 - - - Italy - Netherlands - United Kingdom - Netherlands - Italy - Spain - Hungary - Italy - Netherlands - Netherlands - United States - Canada - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The aim of the Personalized pREvention of Chronic DIseases consortium (PRECeDI) is to provide high-quality, multidisciplinary knowledge through training and research in Personalized Medicine (PM), with specific reference to - prevention of chronic diseases. There is a large consensus that PM is a driver of innovation for research and health care, and also for the health care system and industry as a whole. In order to harness the potential of this new concept, the PRECeDI - consortium provides a cohesive framework for training staff from academic and non-academic (NA) institutions on research topics related to PM, with specific reference to the prevention of chronic diseases where there is a lack of substantial - evidence, though the potential is huge. The acquisition of skills from staff will come from dedicated secondments aimed at training on research topics not available at the home institutions, and attendance to courses, workshops, seminars, - conferences. The goal of secondment is to enable staff to make informed decisions for appropriately serve health care systems, new biotech industries and policy makers at the dawn of the post-genomic era - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Italy - - - PRECeDI - - - H2020-MSCA-RISE-2014 - - - 645740 - - - - - JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN - JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN - - - EUR 148 750 - - - Commercialization of an innovative tomographic reconstruction algorithm (Super-sampling SART)for various geometry setups - - - EUR 148 750 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In this proposal, we would like to advance our high quality and highly flexible multi-purpose three-dimensional tomographic reconstruction algorithm from a state of the art research tool to an innovative commercial software - product. Transmission tomography uses N-1 dimensional images to reconstruct an N-dimensional object. It is applicable on a multitude of applications ranging from scientific to industrial level. Our implementation has already proven its superior image - reconstruction capabilities for incomplete and low signal-to-noise ratio electron tomography and X-ray microscopy data against the established reconstruction algorithms. In addition, the reconstruction time is reduced to between 50% and 90% compared - to other reconstruction methods. Thus, it offers crucial advantages for multi-dimensional image visualization and interpretation, in particular for quantitative information extraction. - - 2017-06-30, closed project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2015 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Germany - - - SuperSART - - - ERC-2015-PoC - - - 693521 - - - - - UNIVERSITY OF BRISTOL - BAUHAUS-UNIVERSITAET WEIMAR - ARISTOTELIO PANEPISTIMIO THESSALONIKIS - UNIVERSITA DEGLI STUDI DEL SANNIO - PANEPISTIMIO PATRON - CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL - VCE VIENNA CONSULTING ENGINEERS ZT GMBH - STIFTELSEN NORGES GEOTEKNISKE INSTITUTT - UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II. - HOCHTIEF ENGINEERING GMBH - - - EUR 909 000 - - - EXperimental Computational Hybrid Assessment of Natural Gas pipelines Exposed to Seismic Risk - - - EUR 909 000 - - - United Kingdom - Germany - Greece - Italy - Greece - Germany - Austria - Norway - Italy - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - EXCHANGE-Risk is an Intersectoral/International Research and Innovation staff exchange scheme between academia and the industry in Europe and North America focusing on mitigating Seismic Risk of buried steel pipeline Networks - that are subjected to ground-imposed permanent deformations. It also aims at developing a Decision Support System for the Rapid Pipeline Recovery to minimize the time required for inspection and rehabilitation in case of a major earthquake. - EXCHANGE-Risk involves novel hybrid experimental and numerical work of the soil-pileline system at a pipe, pipeline and network level integrated with innovative technologies for rapid pipe inspection. The outcome of the project is a series of well - targeted exchanges between the partners (involving more than 30 early stage and experienced researchers) within a well defined framework of innovation that ensures transfer of knowledge between the academia and the industry, Europe and North America - as well wide dissemination of the methodologies and tools developed to the engineering community. - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - United Kingdom - - - EXCHANGE-Risk - - - H2020-MSCA-RISE-2015 - - - 691213 - - - - - HELMHOLTZ ZENTRUM FUR OZEANFORSCHUNG KIEL - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - INSTITUT DE PHYSIQUE DU GLOBE DE PARIS - UNIVERSITA DEGLI STUDI DI MILANO - CESKA ZEMEDELSKA UNIVERZITA V PRAZE - JOANNEUM RESEARCH FORSCHUNGSGESELLSCHAFT MBH - USTAV VIED O ZEMI SLOVENSKEJ AKADEMIE VIED - THERMO FISHER SCIENTIFIC (BREMEN) GMBH - JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN - THE HEBREW UNIVERSITY OF JERUSALEM - CESKA GEOLOGICKA SLUZBA - INSTYTUT PALEOBIOLOGII IM.ROMANA KOZLOWSKIEGO POLSKIEJ AKADEMII NAUK - TECHNISCHE UNIVERSITAET GRAZ - KOBENHAVNS UNIVERSITET - JR-AQUACONSOL GMBH - - - EUR 3 749 331,24 - - - Brachiopods As SEnsitive tracers of gLobal marINe Environment: Insights from alkaline, alkaline Earth metal, and metalloid trace element ratios and isotope systems - - - EUR 3 749 331,24 - - - Germany - Germany - France - Italy - Czech Republic - Austria - Slovakia - Germany - Germany - Israel - Czech Republic - Poland - Austria - Denmark - Austria - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Data on seawater composition since the start of the Phanerozoic eon ~540 million years ago provide essential information for understanding long-term chemical processes of socio-economic dimension like the evolution of life, - land-ocean interaction, atmospheric chemistry, ecosystem adaptation to climate change, oceanic trace metal cycling, and for applied geological processes like the formation of submarine energy resources. Although partly known this knowledge is still - limited pending new methodical prospects and innovative analytical techniques. Following this approach, the proposed ETN "BASE-LiNE Earth" will train early stage researchers (ESRs) who will extend the knowledge of the complex and long-term - Phanerozoic seawater history by the determination of original proxy information preserved in reliable ancient geological archives using cutting edge technologies and experimental approaches. In order to amplify this process the ESRs will be exposed - to academic and non-academic high-tech institutions linking biogeochemical research and training in biology, ecology, geochemistry as well as chemical analytics to engineering and cutting edge analytical instrumentation. Multi- and interdisciplinary - environments will expose our ESRs to highly demanded transferable skills increasing their employability when it comes to job application. "BASE-LiNE Earth" will offer societally important deliverables like time series of past trace element and - isotope cycling and models about ocean material fluxes in and out of the Phanerozoic Ocean. This will be shared in publications, reports and exhibitions. Interactive lecturing material will be offered for education in general and specifically for - high school teachers. Through collaboration with high-tech companies the ETN will contribute to establish both, new approaches for the exploration of hydrocarbon reservoirs and innovative and sophisticated analytical instrumentation for trace element - and isotope measurements. - - 2018-12-31, ongoing project | - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - BASE-LiNE Earth - - - H2020-MSCA-ITN-2014 - - - 643084 - - - - - CONSIGLIO NAZIONALE DELLE RICERCHE - THE UNIVERSITY OF SHEFFIELD - UNIVERSITA DI PISA - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - TARTU ULIKOOL - SCUOLA IMT (ISTITUZIONI, MERCATI, TECNOLOGIE) ALTI STUDI DI LUCCA - GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER - KING'S COLLEGE LONDON - SCUOLA NORMALE SUPERIORE - AALTO-KORKEAKOULUSAATIO - Eidgenössische Technische Hochschule Zürich - TECHNISCHE UNIVERSITEIT DELFT - - - EUR 5 000 000 - - - SoBigData Research Infrastructure - - - EUR 5 917 500 - - - Italy - United Kingdom - Italy - Germany - Estonia - Italy - Germany - United Kingdom - Italy - Finland - Switzerland - Netherlands - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - One of the most pressing and fascinating challenges scientists face today, is understanding the complexity of our globally interconnected society. The big data arising from the digital breadcrumbs of human activities promise - to let us scrutinize the ground truth of individual and collective behaviour at an unprecedented detail and scale. There is an urgent need to harness these opportunities for scientific advancement and for the social good. The main obstacle to this - accomplishment, besides the scarcity of data scientists, is the lack of a large-scale open infrastructure, where big data and social mining research can be carried out. - - 2019-08-31, ongoing project | - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.2."> - - - INFRAIA-1-2014-2015 - Integrating and opening existing national and regional research infrastructures of European interest - - - RIA - Research and Innovation action - - - Italy - - - SoBigData - - - H2020-INFRAIA-2014-2015 - - - 654024 - - - - - BRISTOL NATURAL HISTORY CONSORTIUM - UNIVERSITY OF BRISTOL - UNIVERSITY OF THE WEST OF ENGLAND, BRISTOL - - - EUR 127 855 - - - Bristol Bright Night - - - EUR 127 855 - - - United Kingdom - United Kingdom - United Kingdom - - - Other - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Bristol’s proposal for the Marie Skłodowska-Curie Researchers’ Night programme takes part across 2014 and 2015. Bristol’s programme for Researchers’ Night has an ambition to involve a wide cross-section of researchers across - the city’s two universities centred on the theme ‘Bristol Bright Night’ highlighting the innovative research undertaken by Bristol-based researchers addressing local and global societal challenges. During the Researchers’ Night the city’s waterfront - will be transformed into an Innovation Laboratory giving everyone equal access to ground-breaking research, in particular young and family audiences. Bristol has the advantage of having several world-renowned public venues within a short walk of each - other in its historical centre. These will host the Researchers’ Night 2014 and 2015. Additionally, in 2015 special opportunities will be provided for celebrating the 10th anniversary of the Researchers’ Night, and the programme will also benefit - from Bristol’s designation as European Green Capital in 2015. Bristol’s programme for Researchers’ Night will focus on environmental science and sustainability research conducted locally and through European projects, particularly by Marie - Skłodowska-Curie (MSC) fellows, however, Bristol’s digital and creative media cluster will also be involved. - - 2015-09-30, closed project - - - 2014-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.5."> - - - MSCA-NIGHT-2014 - European Researchers' Night (NIGHT) - - - CSA - Coordination and support action - - - United Kingdom - - - BGCN - - - H2020-MSCA-NIGHT-2014 - - - 633328 - - - - - LINKOPINGS UNIVERSITET - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA - - - EUR 823 500 - - - PEROVSKITE OPTOELECTRONICS - - - EUR 1 233 000 - - - Sweden - United Kingdom - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Chiara Andreoli - Tel.: +3901071781854 - Fax: +39 010 7170817 - - The goal of this project is to develop a lasting collaboration between top class research teams in Europe and China that fosters progress in the broad area of perovskite optoelectronics through progress in materials science, - chemistry, device physics, photophysics, and device engineering. This will be realized via a cross-European, trans-continental network. Such a network is required as perovskite opotoelectronics is a research area that requires strong collaborations - between researchers with different background. More specifically, the PEOPLE network is intended as a key driver for the development of perovskite optoelectronics. Multiple disciplines need to be involved so that PEOPLE can cover the entire knowledge - chain: the design/synthesis of perovskite materials, processing/characterization of perovskite films, photovoltaic applications of perovskites, other emerging optoelectronic devices based on perovskites, device physics and photophysics. The combined - expertise in PEOPLE is essential to achieve a transformative impact. This project regroups leading research teams in the domain of perovskite optoelectronics, with complementary expertise, in an attempt to synergise the research effort in this area. - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Sweden - - - PEOPLE - - - H2020-MSCA-RISE-2015 - - - 691210 - - - - - COOPERACION LATINOAMERICANA DE REDES AVANZADAS - GEANT LIMITED - GEANT VERENIGING - REDE NACIONAL DE ENSINO E PESQUISA - CORPORACION RED NACIONAL ACADEMICA DE TECNOLOGIA AVANZADA - CORPORACION RED UNIVERSITARIA NACIONAL - Consorcio Ecuatoriano para el Desarrollo de Internet Avanzado - CORPORACION UNIVERSITARIA PARA EL DESARROLLO DE INTERNET AC - THE UBUNTUNET ALLIANCE FOR RESEARCH AND EDUCATION NETWORKING - WEST AND CENTRAL AFRICAN RESEARCH AND EDUCATION NETWORK - ARAB STATES RESEARCH AND EDUCATION NETWORK ASREN GEMEINNUTZIGE GMBH - CESNET ZAJMOVE SDRUZENI PRAVNICKYCH OSOB - ETHNIKO DIKTYO EREVNAS TECHNOLOGIAS AE - SURFnet bv - COUNCIL FOR SCIENTIFIC AND INDUSTRIAL RESEARCH - GROUPEMENT D INTERET PUBLIC POUR LERESEAU NATIONAL DE TELECOMMUNICATIONS POUR LA TECHNOLOGIE L ENSEIGNEMENT ET LA RECHERCHE - NEMZETI INFORMACIOS INFRASTRUKTURA FEJLESZTESI IRODA - KORMANYZATI INFORMATIKAI FEJLESZTESI UGYNOKSEG - CARRIBEAN KNOWLEDGE AND LEARNING NETWORK FOUNDATION LIMITED - NATIONAL INFORMATION TECHNOLOGY CENTER - TEIN COOPERATION CENTER FOUNDATION - - - EUR 1 355 972 - - - Middleware for collaborative Applications and Global vIrtual Communities - - - EUR 1 821 872,50 - - - Uruguay - United Kingdom - Netherlands - Brazil - Colombia - Chile - Ecuador - Mexico - Netherlands - Ghana - Germany - Czech Republic - Greece - Netherlands - South Africa - France - Hungary - Hungary - Grenada - Kyrgyzstan - South Korea - - - Other - Other - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Other - Other - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Other - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The MAGIC Project seeks to establish a set of agreements for Europe, Latin America and other participating World Regions, aiming at consolidating and completing the building blocks of middleware necessary for the establishment - of a marketplace of services and real-time applications for international and inter-continental research groups which facilitates mobility and the work of global science communities. More specifically, the project specific goals are: - - 2017-04-30, closed project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.3."> - - - INFRASUPP-7-2014 - e-Infrastructure policy development and international cooperation - - - CSA - Coordination and support action - - - Uruguay - - - MAGIC - - - H2020-INFRASUPP-2014-2 - - - 654225 - - - - - BRUNEL UNIVERSITY LONDON - SIGMA ORIONIS SA - THE UBUNTUNET ALLIANCE FOR RESEARCH AND EDUCATION NETWORKING - UNIVERSITA DEGLI STUDI DI CATANIA - WEST AND CENTRAL AFRICAN RESEARCH AND EDUCATION NETWORK - KUNGLIGA TEKNISKA HOEGSKOLAN - DAR ES SALAAM INSTITUTE OF TECHNOLOGY - KAROLINSKA INSTITUTET - COUNCIL FOR SCIENTIFIC AND INDUSTRIAL RESEARCH - - - EUR 1 339 125 - - - Energising Scientific Endeavour through Science Gateways and e-Infrastructures in Africa - - - EUR 1 339 125 - - - United Kingdom - France - Netherlands - Italy - Ghana - Sweden - Tanzania - Sweden - South Africa - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Other - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - In African Communities of Practice (CoPs), international collaboration and the pursuit of scientific endeavour has faced a major barrier with the lack of access to e-Infrastructures and high performance network infrastructure - enjoyed by European counterparts. With AfricaConnect, the proposed AfricaConnect2 and regional developments, this situation is changing rapidly. In the project Teaming-up for exploiting e-Infrastructures' potential to boost RTDI in Africa (eI4Africa) - it has been demonstrated clearly that it is possible to develop e-Infrastructures in Africa. It has also been demonstrated clearly that, as with the rest of the world, easy to use web portals, or Science Gateways, are needed to help CoPs to easily - access e-Infrastructure facilities and through these collaborate with CoPs across the world. However, a major problem exists: it is very difficult for non-experts to develop Science Gateways and supporting e-Infrastructures. Elements of guides and - supporting materials exist but these are either written for different audiences or out of date. This present Coordination and Support Action, called Energising Scientific Endeavour through Science Gateways and e-Infrastructures in Africa (Sci-GaIA), - therefore proposes to bring together these materials into clearly structured guides and educational documents that can be used to train and support representatives of NRENs, CoPs and, importantly, Universities to develop Science Gateways and other - e-Infrastructures services in Africa. Sci-GaIA plans to work with new and emerging CoPs to develop these exciting technologies, to strengthen e-Infrastructure service provision, especially in terms of open access linked data, and to deliver training - and dissemination workshops. This will give a sustainable foundation on which African e-Infrastructures can be developed and be linked to scientific networks across Africa. Importantly, the results of our project will be usable by CoPs in Europe and - the rest of the world. - - 2017-04-30, closed project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.3."> - - - INFRASUPP-7-2014 - e-Infrastructure policy development and international cooperation - - - CSA - Coordination and support action - - - United Kingdom - - - Sci-GaIA - - - H2020-INFRASUPP-2014-2 - - - 654237 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSITY OF BRISTOL - WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER - JOHANNES GUTENBERG-UNIVERSITAT MAINZ - UNIVERSITEIT UTRECHT - UNIVERSITA DEGLI STUDI ROMA TRE - UNIVERSITY OF DURHAM - UNIVERSITY COLLEGE LONDON - - - EUR 3 661 113,24 - - - Complex RhEologies in Earth dynamics and industrial Processes - - - EUR 3 661 113,24 - - - France - United Kingdom - Germany - Germany - Netherlands - Italy - United Kingdom - United Kingdom - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The CREEP Innovative Training Network is a training and career development platform for early stage researchers (ESRs) in Geodynamics, Mineral Physics, Seismology, Fluid Mechanics, and Materials Sciences. It aims to structure - the collaboration in research and doctoral training between 10 leading academic centers in Earth Sciences in Europe: the CNRS (FR), represented by Geosciences Montpellier and the FAST Orsay, the universities of Bristol, Durham and UCL (UK), Munster - and Mainz (DE), Roma TRE (IT) and Utrecht (NL), and as a partner organization: ETH (CH), and 11 partner organizations whose activity encompasses a variety of industrial applications of rheology: oil (Baker Hughes, Schlumberger) and chemical - industries (AkzoNobel), glass (Schott) and steel (APERAM) producers, and high-technology SMEs (Rockfield, IGEM, GMuG, MP Strumenti, Geospatial Research, Reykjavik Geothermal). - - - 2019-03-31, ongoing project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - France - - - CREEP - - - H2020-MSCA-ITN-2014 - - - 642029 - - - - - LUNDS UNIVERSITET - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - CONSORCIO PARA EL DISENO, CONSTRUCCION, EQUIPAMIENTO Y EXPLOTACION DELCENTRO DE LASERES PULSADOS ULTRACORTOS ULTRAINTENSOS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - ELETTRA - SINCROTRONE TRIESTE SCPA - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - FORSCHUNGSVERBUND BERLIN EV - GSI HELMHOLTZZENTRUM FUER SCHWERIONENFORSCHUNG Gmbh - HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF EV - FUNDACIO INSTITUT DE CIENCIES FOTONIQUES - MEDZINARODNE LASEROVE CENTRUM - INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU FIZICA LASERILOR PLASMEI SI RADIATIEI - FYZIKALNI USTAV AV CR V.V.I - ASSOCIACAO DO INSTITUTO SUPERIOR TECNICO PARA A INVESTIGACAO E DESENVOLVIMENTO - LABORATORIO EUROPEO DI SPETTROSCOPIE NON LINEARI - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - WOJSKOWA AKADEMIA TECHNICZNA IM JAROSLAWA DABROWSKIEGO - POLITECNICO DI MILANO - STICHTING KATHOLIEKE UNIVERSITEIT - SCIENCE AND TECHNOLOGY FACILITIES COUNCIL - UNIVERSITY OF STRATHCLYDE - UNIVERSIDADE DE COIMBRA - LATVIJAS UNIVERSITATE - SZEGEDI TUDOMANYEGYETEM - STICHTING VU - VILNIAUS UNIVERSITETAS - - - EUR 10 000 000 - - - The Integrated Initiative of European Laser Research Infrastructures - - - EUR 10 000 000,89 - - - Sweden - France - Spain - France - Italy - Greece - Germany - Germany - Germany - Spain - Slovakia - Romania - Czech Republic - Portugal - Italy - Germany - Poland - Italy - Netherlands - United Kingdom - United Kingdom - Portugal - Latvia - Hungary - Netherlands - Lithuania - - - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - LASERLAB-EUROPE is the European consortium of major national laser research infrastructures, covering advanced laser science and applications in most domains of research and technology, with particular emphasis on areas with - high industrial and social impact, such as bio- and nanophotonics, material analyses, biology and medicine. - - - 2019-11-30, ongoing project - - - 2015-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.2."> - - - INFRAIA-1-2014-2015 - Integrating and opening existing national and regional research infrastructures of European interest - - - RIA - Research and Innovation action - - - Sweden - - - LASERLAB-EUROPE - - - H2020-INFRAIA-2014-2015 - - - 654148 - - - - - HELSINGIN YLIOPISTO - EURO-ARGO ERIC - EISCAT SCIENTIFIC ASSOCIATION - CONSIGLIO NAZIONALE DELLE RICERCHE - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER - FORSCHUNGSZENTRUM JULICH GMBH - ISTITUTO NAZIONALE DI GEOFISICA E VULCANOLOGIA - NATURAL ENVIRONMENT RESEARCH COUNCIL - Euro-Mediterranean Seismological Centre - Eidgenössische Technische Hochschule Zürich - UNIVERSITAET BREMEN - UNIVERSITEIT VAN AMSTERDAM - UNIVERSITA DEL SALENTO - INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE - UMWELTBUNDESAMT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (UBA GMBH) - GOETEBORGS UNIVERSITET - MARINE BIOLOGICAL ASSOCIATION OF THE UNITED KINGDOM - THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS - DEUTSCHES KLIMARECHENZENTRUM GMBH - NORGES FORSKNINGSRAD - EUROPEAN MOLECULAR BIOLOGY LABORATORY - UNIVERSITETET I TROMSOE - EUROGOOS - CONSORCIO PARA EL DISENO, CONSTRUCCION, EQUIPAMIENTO Y EXPLOTACION DE LA PLATAFORMA OCEANICA DE CANARIAS - KOBENHAVNS UNIVERSITET - ILMATIETEEN LAITOS - LUNDS UNIVERSITET - UNIVERSITA DEGLI STUDI DELLA TUSCIA - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - HELMHOLTZ ZENTRUM FUR OZEANFORSCHUNG KIEL - NORSK INSTITUTT FOR LUFTFORSKNING STIFTELSE - CARDIFF UNIVERSITY - THE UNIVERSITY OF EDINBURGH - CSC-TIETEEN TIETOTEKNIIKAN KESKUS OY - CINECA CONSORZIO INTERUNIVERSITARIO - STICHTING EGI - - - EUR 14 683 534,25 - - - Environmental Research Infrastructures Providing Shared Solutions for Science and Society - - - EUR 14 998 034,25 - - - Finland - France - Sweden - Italy - France - France - Germany - Italy - United Kingdom - France - Switzerland - Germany - Netherlands - Italy - France - Austria - Sweden - United Kingdom - United Kingdom - Germany - Norway - Germany - Norway - Belgium - Spain - Denmark - Finland - Sweden - Italy - France - Germany - Norway - United Kingdom - United Kingdom - Finland - Italy - Netherlands - - - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Other - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Other - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - Research Organisations - Other - - ENVRIPLUS is a cluster of research infrastructures (RIs) for Environmental and Earth System sciences, built around ESFRI roadmap and associating leading e-infrastructures and Integrating Activities together with technical - specialist partners. ENVRIPLUS is driven by 3 overarching goals: 1) favoring cross-fertilization between infrastructures, 2) implementing innovative concepts and devices across RIs, and 3) facilitating research and innovation in the field of - environment to an increasing number of users outside the RIs. ENVRIPLUS organizes its activities along a main strategic plan where sharing multi-disciplinary expertise will be most effective. It aims to improve Earth observation monitoring systems - and strategies, including actions towards harmonization and innovation, to generate common solutions to many shared information technology and data related challenges, to harmonize policies for access and provide strategies for knowledge transfer - amongst RIs. ENVRIPLUS develops guidelines to enhance trans-disciplinary use of data and data-products supported by applied use-cases involving RIs from different domains. ENVRIPLUS coordinates actions to improve communication and cooperation, - addressing Environmental RIs at all levels, from management to end-users, implementing RI-staff exchange programs, generating material for RI personnel, and proposing common strategic developments and actions for enhancing services to users and - evaluating the socio-economic impacts. ENVRIPLUS is expected to facilitate structuration and improve quality of services offered both within single RIs and at pan-RI level. It promotes efficient and multi-disciplinary research offering new - opportunities to users, new tools to RI managers and new communication strategies for environmental RI communities. The produced solutions, services and other project results are made available to all environmental RI initiatives, thus contributing - to the development of a consistent European RI ecosystem. - - 2019-04-30, ongoing project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-4-2014-2015 - Implementation and operation of cross-cutting services and solutions for clusters of ESFRI and other relevant research infrastructure initiatives - - - RIA - Research and Innovation action - - - Finland - - - ENVRI PLUS - - - H2020-INFRADEV-1-2014-1 - - - 654182 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - KING'S COLLEGE LONDON - HUMBOLDT-UNIVERSITAET ZU BERLIN - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - UNIVERSITAT DE BARCELONA - AALTO-KORKEAKOULUSAATIO - DANMARKS TEKNISKE UNIVERSITET - BAYERISCHE AKADEMIE DER WISSENSCHAFTEN - CSC-TIETEEN TIETOTEKNIIKAN KESKUS OY - BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION - PINTAIL LTD - - - EUR 4 910 624,48 - - - The Novel Materials Discovery Laboratory - - - EUR 4 910 624,48 - - - Germany - United Kingdom - Germany - United Kingdom - Spain - Finland - Denmark - Germany - Finland - Spain - Ireland - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Other - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Essentially every new commercial product, be they smart phones, solar cells, batteries, transport technology, artificial hips, etc., depends on improved or even novel materials. Computational materials science is increasingly - influential as a method to identify such critical materials for both R&D. Enormous amounts of data, precious but heterogeneous and difficult to access or utilise, are already stored in repositories scattered across Europe. The NoMaD CoE will open - new HPC opportunities by enabling access to this data and delivering powerful new tools to search, retrieve and manage it. - - 2018-10-31, ongoing project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.3."> - - - EINFRA-5-2015 - Centres of Excellence for computing applications - - - RIA - Research and Innovation action - - - Germany - - - NoMaD - - - H2020-EINFRA-2015-1 - - - 676580 - - - - - STICHTING DELTARES - AALTO-KORKEAKOULUSAATIO - CENTRO DE ESTUDIOS Y EXPERIMENTACION DE OBRAS PUBLICAS - CEDEX - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - DHI - INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU GEOLOGIE SI GEOECOLOGIE MARINA-GEOECOMAR - HR WALLINGFORD LIMITED - HAMBURGISCHE SCHIFFBAU-VERSUCHSANSTALT GMBH - INTERNATIONAL ASSOCIATION OF HYDRAULIC ENGINEERING AND RESEARCH - INSTYTUT BUDOWNICTWA WODNEGO POLSKIEJ AKADEMII NAUK - INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER - LOUGHBOROUGH UNIVERSITY - LABORATORIO NACIONAL DE ENGENHARIA CIVIL - GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER - NATURAL ENVIRONMENT RESEARCH COUNCIL - NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU - SAMUI DESIGN AND MANAGEMENT LIMITED - THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN - UNIVERSITA DEGLI STUDI DI CATANIA - UNIVERSIDAD DE CANTABRIA - UNIVERSITY OF HULL - UNIVERSITAT POLITECNICA DE CATALUNYA - UNIVERSIDADE DO PORTO - UNIVERSITEIT TWENTE - - - EUR 9 979 376,17 - - - HYDRALAB+ Adapting to climate change - - - EUR 9 979 376,17 - - - Netherlands - Finland - Spain - France - Denmark - Romania - United Kingdom - Germany - Netherlands - Poland - France - United Kingdom - Portugal - Germany - United Kingdom - Norway - United Kingdom - United Kingdom - Italy - Spain - United Kingdom - Spain - Portugal - Netherlands - - - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Other - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - HYDRALAB is an advanced network of environmental hydraulic institutes in Europe, which has been effective in providing access to a suite of major and unique environmental hydraulic facilities from across the whole European scientific community. - - 2019-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.2."> - - - INFRAIA-1-2014-2015 - Integrating and opening existing national and regional research infrastructures of European interest - - - RIA - Research and Innovation action - - - Netherlands - - - HYDRALAB-PLUS - - - H2020-INFRAIA-2014-2015 - - - 654110 - - - - - PSIQUADRO SOCIETA COOPERATIVA - ISTITUTO NAZIONALE DI FISICA NUCLEARE - UNIVERSITA DEGLI STUDI DI PERUGIA - OBSERVA - UNIVERSITA POLITECNICA DELLE MARCHE - - - EUR 249 050 - - - SHAring Researchers’ Passion for Excellence and Results. European Reserarchers' Night in the Centre of Italy 2014 - 2015 - - - EUR 332 065 - - - Italy - Italy - Italy - Italy - Italy - - - Other - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - - The SHARPER project (Sharing Researchers’ Passion for Excellence and Results - The European Researchers’ Night in the Centre of Italy, 2014 – 2015) wants to make the researchers’ quest for excellence accessible to everybody in - cities and communities where researchers act and live. - - - 2015-12-31, closed project - - - 2014-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.5."> - - - MSCA-NIGHT-2014 - European Researchers' Night (NIGHT) - - - CSA - Coordination and support action - - - Italy - - - SHARPER - - - H2020-MSCA-NIGHT-2014 - - - 633367 - - - - - STICHTING ASTRON, NETHERLANDS INSTITUTE FOR RADIO ASTRONOMY - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - ISTITUTO NAZIONALE DI ASTROFISICA - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - JOINT INSTITUTE FOR VERY LONG BASELINE INTERFEROMETRY AS A EUROPEAN RESEARCH INFRASTRUCTURE CONSORTIUM (JIV-ERIC) - JOINT INSTITUTE FOR V.L.B.I. IN EUROPE (J.I.V.E.) - INSTITUTO NACIONAL DE TECNICA AEROESPACIAL ESTEBAN TERRADAS - THE UNIVERSITY OF EDINBURGH - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - THE OPEN UNIVERSITY - FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG - STICHTING VU - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - UNIVERSITEIT VAN AMSTERDAM - UNIVERSIDAD DE GRANADA - STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN - INSTITUT D'ESTUDIS ESPACIALS DE CATALUNYA FUNDACION - INSTITUTO DE FISICA DE ALTAS ENERGIAS - UNIVERSIDAD COMPLUTENSE DE MADRID - ISTITUTO NAZIONALE DI FISICA NUCLEARE - SCIENCE AND TECHNOLOGY FACILITIES COUNCIL - STIFTUNG DEUTSCHES ELEKTRONEN-SYNCHROTRON DESY - SURFnet bv - GTD SISTEMAS DE INFORMACION SA - - - EUR 14 991 194 - - - Astronomy ESFRI and Research Infrastructure Cluster - - - EUR 14 991 194 - - - Netherlands - France - Italy - United Kingdom - Netherlands - Netherlands - Spain - United Kingdom - Germany - United Kingdom - Germany - Netherlands - France - Netherlands - Spain - Netherlands - Spain - Spain - Spain - Italy - United Kingdom - Germany - Netherlands - Spain - - - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - ASTERICS (Astronomy ESFRI & Research Infrastructure Cluster) aims to address the cross-cutting synergies and common challenges shared by the various Astronomy ESFRI facilities (SKA, CTA, KM3Net & E-ELT). It brings - together for the first time, the astronomy, astrophysics and particle astrophysics communities, in addition to other related research infrastructures. The major objectives of ASTERICS are to support and accelerate the implementation of the ESFRI - telescopes, to enhance their performance beyond the current state-of-the-art, and to see them interoperate as an integrated, multi-wavelength and multi-messenger facility. An important focal point is the management, processing and scientific - exploitation of the huge datasets the ESFRI facilities will generate. ASTERICS will seek solutions to these problems outside of the traditional channels by directly engaging and collaborating with industry and specialised SMEs. The various ESFRI - pathfinders and precursors will present the perfect proving ground for new methodologies and prototype systems. In addition, ASTERICS will enable astronomers from across the member states to have broad access to the reduced data products of the ESFRI - telescopes via a seamless interface to the Virtual Observatory framework. This will massively increase the scientific impact of the telescopes, and greatly encourage use (and re-use) of the data in new and novel ways, typically not foreseen in the - original proposals. By demonstrating cross-facility synchronicity, and by harmonising various policy aspects, ASTERICS will realise a distributed and interoperable approach that ushers in a new multi-messenger era for astronomy. Through an active - dissemination programme, including direct engagement with all relevant stakeholders, and via the development of citizen scientist mass participation experiments, ASTERICS has the ambition to be a flagship for the scientific, industrial and societal - impact ESFRI projects can deliver. - - 2019-04-30, ongoing project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-4-2014-2015 - Implementation and operation of cross-cutting services and solutions for clusters of ESFRI and other relevant research infrastructure initiatives - - - RIA - Research and Innovation action - - - Netherlands - - - ASTERICS - - - H2020-INFRADEV-1-2014-1 - - - 653477 - - - - - INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT - UNIVERSITE DE LORRAINE - UNIVERSITA DEGLI STUDI DI PADOVA - AALBORG UNIVERSITET - NOVITOM SAS - AARHUS UNIVERSITET - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSITE GRENOBLE ALPES - THE UNIVERSITY OF AUCKLAND - THE NEW ZEALAND INSTITUTE FOR PLANT AND FOOD RESEARCH LIMITED - UNIVERSIDAD NACIONAL AUTONOMA DE MEXICO - SAITAMA UNIVERSITY - NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY - - - EUR 175 500 - - - PROviding new insighT into INteractions between soil fUnctions and Structure - - - EUR 459 000 - - - France - France - Italy - Denmark - France - Denmark - France - France - New Zealand - New Zealand - Mexico - Japan - Japan - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The PROTINUS proposal assembles a multi-disciplinary team to combine advanced, applied and theoretical research to create a new standard in imaging, analysing, modelling and predicting the interactions between soil structure - and soil functions. Soil structure impacts a whole range of services soil renders to ecosystems, including for example contaminant filtering, carbon storage, root growth, and microbiological diversity. - - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - France - - - PROTINUS - - - H2020-MSCA-RISE-2014 - - - 645717 - - - - - WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER - UNIVERSITA DELLA CALABRIA - UNIVERSITA DEGLI STUDI DI CATANIA - THE GLASGOW CALEDONIAN UNIVERSITY - UNIWERSYTET WARSZAWSKI - FONDATION NATIONALE DES SCIENCES POLITIQUES - SYDDANSK UNIVERSITET - WIRTSCHAFTSUNIVERSITAT WIEN - THE COLLEGE OF MANAGEMENT ACADEMIC STUDIES - UNIVERSIDAD DE SEVILLA - IMPACT HUB BERLIN GMBH - THE HUB SICILIA SOCIETA COOPERATIVA - MUJERES SUPERVIVIENTES DE VIOLENCIAS DE GENERO: DESDE EL SUR CONSTRUYENDO LA IGUALDAD - MALMO FOTBOLLFORENING - LES ATELIERS DE ENTREPRENEURIAT HUMANISTE - FUNDACJA FEMINOTEKA - social - design - business Verein zur Förderung der Kreativ- und Sozialwisrtschaft, gabarage upcycling design - MINGA 1212 SOCIAL ENTERPRISE ARENA - INVERCLYDE COMMUNITY DEVELOPMENT TRUST - FAIVELOVITZ RONNY ADINA - COOMPANION KOOPERATIV UTVECKLING SKANE EK. FOR. - - - EUR 1 192 500 - - - For a Better Tomorrow: Social Enterprises on the Move - - - EUR 1 192 500 - - - Germany - Italy - Italy - United Kingdom - Poland - France - Denmark - Austria - Israel - Spain - Germany - Italy - Spain - Sweden - France - Poland - Austria - Israel - United Kingdom - Israel - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Other - Other - Other - Other - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The project “For a Better Tomorrow: Social Enterprises on the Move (FAB-MOVE)” brings together researchers and practitioners in order to explore the question of how social enterprises can grow and flourish. These objectives - will be achieved through a carefully crafted network of academic and non-academic partner organisations co-operating worldwide. - - 2018-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Germany - - - FAB-MOVE - - - H2020-MSCA-RISE-2015 - - - 688991 - - - - - UNIVERSITY OF LEEDS - UNIVERSITY OF HULL - Pannon Egyetem - THE UNIVERSITY OF SHEFFIELD - - - EUR 405 000 - - - Development of flexible pyrolysis-catalysis processing of waste plastics for selective production of high value products through research and innovation - - - EUR 634 500 - - - United Kingdom - United Kingdom - Hungary - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The Research and Innovation Staff Exchange project aims to develop and maintain long term collaborations between Universities in the European Union with China and Australia. The collaboration is centered around the goal of - advancing beyond the current state-of-the-art of wastes pyrolysis through staff exchanges with world-leading researchers in pyrolysis process engineering, catalysis and modelling/simulation. Advancement beyond the state-of-the-art is the innovation - of introducing novel catalysts into the pyrolysis process to produce the next generation of advanced thermal treatment technologies for plastic wastes. - - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - United Kingdom - - - FLEXI-PYROCAT - - - H2020-MSCA-RISE-2014 - - - 643322 - - - - - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH - OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN - UNIVERSITE CATHOLIQUE DE LOUVAIN - INSTITUTE OF NUCLEAR RESEARCH AND NUCLEAR ENERGY - BULGARIAN ACADEMY OF SCIENCES - RUDER BOSKOVIC INSTITUTE - FYZIKALNI USTAV AV CR V.V.I - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - STIFTUNG DEUTSCHES ELEKTRONEN-SYNCHROTRON DESY - JOHANNES GUTENBERG-UNIVERSITAT MAINZ - KARLSRUHER INSTITUT FUER TECHNOLOGIE - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN - MAGYAR TUDOMANYOS AKADEMIA WIGNER FIZIKAI KUTATOKOZPONT - TEL AVIV UNIVERSITY - FONDAZIONE BRUNO KESSLER - ISTITUTO NAZIONALE DI FISICA NUCLEARE - VILNIAUS UNIVERSITETAS - UNIVERSITETET I BERGEN - AKADEMIA GORNICZO-HUTNICZA IM. STANISLAWA STASZICA W KRAKOWIE - LABORATORIO DE INSTRUMENTACAO E FISICA EXPERIMENTAL DE PARTICULAS - INSTITUT JOZEF STEFAN - CENTRO DE INVESTIGACIONES ENERGETICAS, MEDIOAMBIENTALES Y TECNOLOGICAS-CIEMAT - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - INSTITUTO DE FISICA DE ALTAS ENERGIAS - INSTITUTO TECNOLOGICO DE ARAGON - LUNDS UNIVERSITET - SCIENCE AND TECHNOLOGY FACILITIES COUNCIL - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - UNIVERSITY COLLEGE LONDON - UNIVERSITY OF BRISTOL - UNIVERSITY OF GLASGOW - THE UNIVERSITY OF LIVERPOOL - THE UNIVERSITY OF MANCHESTER - THE UNIVERSITY OF BIRMINGHAM - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - Eidgenössische Technische Hochschule Zürich - UNIVERSITE DE GENEVE - - - EUR 10 000 000 - - - Advanced European Infrastructures for Detectors at Accelerators - - - EUR 12 909 986,73 - - - Switzerland - Austria - Belgium - Bulgaria - Croatia - Czech Republic - France - France - Germany - Germany - Germany - Germany - Germany - Hungary - Israel - Italy - Italy - Lithuania - Norway - Poland - Portugal - Slovenia - Spain - Spain - Spain - Spain - Sweden - United Kingdom - United Kingdom - United Kingdom - United Kingdom - United Kingdom - United Kingdom - United Kingdom - United Kingdom - United Kingdom - Switzerland - Switzerland - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Particle physics is at the forefront of the ERA, attracting a global community of more than 10,000 scientists. With the upgrade of the LHC and the preparation of new experiments, the community will have to overcome - unprecedented challenges in order to answer fundamental questions concerning the Higgs boson, neutrinos, and physics beyond the Standard Model. Major developments in detector technology are required to ensure the success of these endeavours. - - - 2019-04-30, ongoing project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.2."> - - - INFRAIA-1-2014-2015 - Integrating and opening existing national and regional research infrastructures of European interest - - - RIA - Research and Innovation action - - - Switzerland - - - AIDA-2020 - - - H2020-INFRAIA-2014-2015 - - - 654168 - - - - - "NATIONAL CENTER FOR SCIENTIFIC RESEARCH ""DEMOKRITOS""" - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - UNIVERSITE DE MONS - BONUS THERAPEUTIC LTD - BIOIMAG SOLUCIONES DE CONTRASTE SL - TEXNOLOGIKES LYSEIS BIOEKPOMPIS OE - - - EUR 472 500 - - - Multimodal imaging of the in vivo fate of bone transplants - - - EUR 472 500 - - - Greece - Spain - Belgium - Israel - Spain - Greece - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The main objective of VIVOIMAG is to develop bone implants including a new contrast agent sensitive to enzymatic activity of metaloproteases, which will permit for the first time to follow the integration and cell - differentiation activity in bone tissue bioreactors in vitro and in grafts in vivo using existing non invasive magnetic resonance imaging techniques. The proposal aims at integrating a magnetically functionalized extracellular matrix material into - the bone scaffolds, seeding them with cells, implanting them in animal models and following the fate of the implants in vivo using MRI. The aim is to obtain similar results with the magnetically modified scaffolds as the ones obtained currently but - having now endowed the grafts with enzymatic reporting activity that can be monitored noninvasively in the living animal. There are currently no methods to detect in situ and in vivo this enzymatic activity without previously sacrificing the - transplanted animals, therefore the successful accomplishment of this project would have huge and prolonged impact in the medical field of tissue regeneration. - - 2019-05-31, ongoing project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Greece - - - VIVOIMAG - - - H2020-MSCA-RISE-2014 - - - 645757 - - - - - UNIVERSITAET HAMBURG - BIOSYNTIA APS - CHALMERS TEKNISKA HOEGSKOLA AB - CHR. HANSEN A/S - DSM FOOD SPECIALTIES BV - Eidgenössische Technische Hochschule Zürich - STICHTING VU - TECHNISCHE UNIVERSITAET BERLIN - THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN - THE UNIVERSITY OF EDINBURGH - RIJKSUNIVERSITEIT GRONINGEN - UNIVERSITY OF YORK - - - EUR 3 987 358,20 - - - Synthetic Circuits for Robust Orthogonal Production - - - EUR 3 987 358,20 - - - Germany - Denmark - Sweden - Denmark - Netherlands - Switzerland - Netherlands - Germany - United Kingdom - United Kingdom - Netherlands - United Kingdom - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The repertoire of industrially produced fine chemicals in various biological systems will rapidly expand using the tools from the emerging field of synthetic biology. However, the high-level production of non-natural products - or de novo activities through synthetic circuits compromises the integrity of host organisms, which significantly impacts or even prevents the development of an industrial pipeline. Our ability to exploit the potential of synthetic biology for - industrial production is constrained by our understanding of the integrated cell response when introducing a new synthetic circuit into the homeostatic network of the cell. SynCrop’s main goal is to establish a European Training Network that merges - the fragmented scientific expertise in theoretical, experimental and application-driven quantitative biology to educate the next generation of researchers to construct modular and tunable synthetic circuits and foster the development of novel - production platforms for food additives (e.g. vitamins, carotenoids and exopolysaccharides). Researchers with inter-disciplinary skills in both experimental and computational biology are needed to solve complex application-driven problems. SynCrop - brings together ten academic partners from quantitative biology, cell engineering, microbial physiology and mathematical modelling fields and six industrial partners, including key experts in metabolic engineering and industrial biotechnology. The - consortium will provide 15 early-stage researchers with cutting-edge multi-disciplinary research training, through tailored research projects, rigorous exchange of expertise among researchers and partners, and participation in specialised courses, - workshops and conferences augmented by extensive training in complementary skills. SynCrop will generate a strong cohort of highly-employable scientists with unique inter-disciplinary and intersectoral skills to address complex questions and develop - innovative biotechnological processes. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - SynCrop - - - H2020-MSCA-ITN-2017 - - - 764591 - - - - - FONDATION DE L'INSTITUT DE RECHERCHE IDIAP - PHILIPS ELECTRONICS NEDERLAND B.V. - UNIVERSITE PAUL SABATIER TOULOUSE III - UNIVERSITAIR ZIEKENHUIS ANTWERPEN - FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG - STICHTING KATHOLIEKE UNIVERSITEIT - INESC ID - INSTITUTO DE ENGENHARIADE SISTEMAS E COMPUTADORES, INVESTIGACAO E DESENVOLVIMENTO EM LISBOA - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM - STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS - UNIVERSITAET AUGSBURG - THE UNIVERSITY OF SHEFFIELD - - - EUR 3 856 029,12 - - - Training Network on Automatic Processing of PAthological Speech - - - EUR 3 856 029,12 - - - Switzerland - Netherlands - France - Belgium - Germany - Netherlands - Portugal - Germany - Belgium - Netherlands - Germany - United Kingdom - - - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - There are an increasing number of people across Europe with debilitating speech pathologies (e.g., due to stroke, Parkinson's, etc). These groups face communication problems that can lead to social exclusion. They are now - being further marginalised by a new wave of speech technology that is increasingly woven into everyday life but which is not robust to atypical speech. TAPAS is proposing a programme of pathological speech research, that aims to transform the - well-being of these people. - - 2021-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Switzerland - - - TAPAS - - - H2020-MSCA-ITN-2017 - - - 766287 - - - - - UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6 - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSITA DEGLI STUDI DI PALERMO - UNIVERSIDAD DE SALAMANCA - UNIVERSITAET HAMBURG - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - UNIVERSITY OF ESSEX - UNIVERSITEIT UTRECHT - FONDATION NATIONALE DES SCIENCES POLITIQUES - NATURAL ENVIRONMENT RESEARCH COUNCIL - ISTITUTO NAZIONALE DI OCEANOGRAFIA E DI GEOFISICA SPERIMENTALE - Ministry of National Infrastructure, Energy and Water Resources - - - EUR 3 893 087,88 - - - Understanding the Mediterranean Salinity Crisis - - - EUR 3 893 087,88 - - - France - France - Italy - Spain - Germany - Spain - United Kingdom - Netherlands - France - United Kingdom - Italy - Israel - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - As society moves into an era where environmental change has an ever-growing place in the political agenda, the demand for a new generation of scientists working at the interface between the natural and social sciences is - growing. SALTGIANT contributes to satisfy this demand within a rare cross-disciplinary network of natural and social scientists dedicated to understanding the formation of the Mediterranean Salt Giant, one of the largest salt deposits on Earth, and - its implications for sub-seafloor microbial life, risk assessment in the oil industry, geo-economics of the Mediterranean region and the history of oceanography. SALTGIANT will bring together 22 academic organizations (11 beneficiaries, 11 partners), - 2 private sector Oil&Gas companies and 1 specialist in transferable skills training from 8 European countries to stimulate interdisciplinary and intersectorial knowledge exchange between geologists, geophysicists, geochemists, microbiologist, - geographers and historians in a network with PhD students at its core. SALTGIANT combines (i) geological and geochemical field work, (ii) laboratory measurements and experiments, (iii) numerical modeling at a wide range of spatial and temporal scales - and (iv) empirical social sciences data collection and analysis, guaranteeing exposure of the research fellows to state-of-the-art scientific knowledge and hands-on practical training in a field rich in applications of both intellectual and societal - relevance. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - France - - - SALTGIANT - - - H2020-MSCA-ITN-2017 - - - 765256 - - - - - STICHTING NATURALIS BIODIVERSITY CENTER - JUSTUS-LIEBIG-UNIVERSITAET GIESSEN - MUZEUL NATIONAL DE ISTORIE NATURALA GRIGORE ANTIPA - UNIVERSITEIT UTRECHT - GIMARIS - BRUNEL UNIVERSITY LONDON - UNIVERSITY OF BRISTOL - THE UNIVERSITY OF READING - UNIVERSITATEA DIN BUCURESTI - UNIVERSITAET BREMEN - - - EUR 3 784 088,60 - - - Drivers of Pontocaspian biodiversity RIse and DEmise - - - EUR 3 784 088,60 - - - Netherlands - Germany - Romania - Netherlands - Netherlands - United Kingdom - United Kingdom - United Kingdom - Romania - Germany - - - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Since the 1930s, the unique endemic aquatic biota of the Caspian-Black Sea region is facing a biodiversity crisis as it is severely affected by anthropogenic activities such as habitat destruction, invasive species and - pollution. Understanding long-term natural biotic and abiotic drivers of lake system change and biotic response to perturbations in the past 2 Ma – i.e. gradual, rapid and/or threshold responses – is absolutely necessary to assess the current - response of Pontocaspian biota to rising natural- and human-induced perturbations. The Pontocaspian example mirrors the complex global ecological and biodiversity challenge due to Global Change. This challenge can only be addressed through an - integrated cross-disciplinary research involving climate, earth- and bio-sciences. PRIDE (Pontocaspian biodiversity RIse and DEmise) is a fully integrated academia-industry training network of scientists with complementary cutting-edge competences. - PRIDE focuses on the evolution of Pontocaspian biota over the past 2 million years. The extraordinary endemic biodiversity, coupled with a high-amplitude record of palaeoenvironmental change, makes it an ideal system to study drivers of past and - current biodiversity crises. By linking Pontocaspian palaeoenvironmental and biodiversity changes we will reconstruct biological resilience to environmental change and apply this knowledge to the current Pontocaspian biodiversity crisis to model - future diversity shifts under different Global Change scenarios. PRIDE will provide outstanding interdisciplinary technical training, new skills acquisition and career development for 15 early stage researchers. An innovative outreach plan will - deliver our results to stakeholders and the public. PRIDE results from existing, successful collaborative relationships and will expand to include 17 first-class private and academic geological and biological institutions allowing Europe to remain - world-leading in integrated studies of biodiversity change. - - 2019-02-28, ongoing project | - - - 2015-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Netherlands - - - PRIDE - - - H2020-MSCA-ITN-2014 - - - 642973 - - - - - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - FORSCHUNGSZENTRUM JULICH GMBH - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - AGENZIA NAZIONALE PER LE NUOVE TECNOLOGIE, L'ENERGIA E LO SVILUPPO ECONOMICO SOSTENIBILE - CENTRE EUROPEEN DE RECHERCHE ET DE FORMATION AVANCEE EN CALCUL SCIENTIFIQUE - INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK - UNIVERSITA DEGLI STUDI DI TRENTO - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - UNIVERSITY OF BATH - THE CYPRUS INSTITUTE - CONSIGLIO NAZIONALE DELLE RICERCHE - UNIVERSITE LIBRE DE BRUXELLES - BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION - - - EUR 5 403 491 - - - Energy oriented Centre of Excellence for computer applications - - - EUR 5 689 521,11 - - - France - Germany - Germany - Italy - France - Poland - Italy - Germany - United Kingdom - Cyprus - Italy - Belgium - Spain - - - Research Organisations - Research Organisations - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - - The aim of the present proposal is to establish an Energy Oriented Centre of Excellence for computing applications, (EoCoE). EoCoE (pronounce “Echo”) will use the prodigious potential offered by the ever-growing computing - infrastructure to foster and accelerate the European transition to a reliable and low carbon energy supply. To achieve this goal, we believe that the present revolution in hardware technology calls for a similar paradigm change in the way application - codes are designed. EoCoE will assist the energy transition via targeted support to four renewable energy pillars: Meteo, Materials, Water and Fusion, each with a heavy reliance on numerical modelling. These four pillars will be anchored within a - strong transversal multidisciplinary basis providing high-end expertise in applied mathematics and HPC. - - 2018-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.3."> - - - EINFRA-5-2015 - Centres of Excellence for computing applications - - - RIA - Research and Innovation action - - - France - - - EoCoE - - - H2020-EINFRA-2015-1 - - - 676629 - - - - - ALBUFERA ENERGY STORAGE SL - UNIVERSITY OF LEICESTER - SCIONIX LIMITED - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - TECHNISCHE UNIVERSITAET GRAZ - UNIVERSITY OF SOUTHAMPTON - DANMARKS TEKNISKE UNIVERSITET - - - EUR 2 998 130 - - - Sulfur-Aluminium Battery with Advanced Polymeric Gel Electrolytes - - - EUR 2 998 130 - - - Spain - United Kingdom - United Kingdom - Spain - Austria - United Kingdom - Denmark - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Sulfur-Aluminium Battery with Advanced Polymeric Gel Electrolytes (SALBAGE) - - 2020-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-01-2016-2017 - FET-Open research and innovation actions - - - RIA - Research and Innovation action - - - Spain - - - SALBAGE - - - H2020-FETOPEN-1-2016-2017 - - - 766581 - - - - - DANMARKS TEKNISKE UNIVERSITET - BANG & OLUFSEN AS - FORCE TECHNOLOGY - UNIVERSITE DE NANTES - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - DXO LABS - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - BANGOR UNIVERSITY - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - - - EUR 4 076 702,28 - - - Hyperrealistic Imaging Experience - - - EUR 4 076 702,28 - - - Denmark - Denmark - Denmark - France - France - France - United Kingdom - United Kingdom - United Kingdom - Germany - Germany - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - - The aim of realistic digital imaging is the creation of high quality imagery, which faithfully represents the physical environment. The ultimate goal is to create images, which are perceptually indistinguishable from a real - scene. The RealVision network brings together leading universities, centers focused on industrial development and companies in Multimedia, Optics, Visual Communication, Visual Computing, Computer Graphics and Human Vision research across Europe, with - the aim of training a new generation of scientists, technologists, and entrepreneurs that will move Europe into a leading role in innovative hyper-realistic imaging technologies. Current imaging technologies capture only a fraction of visual - information that the human eye can see. The colours and dynamic range are inadequate for most real-world scenes and not all depth cues required for natural 3D vision are captured. This limits the realism of the experience and has hampered the - introduction of 3D technology. Advancement in imaging technologies makes it possible to circumvent these bottlenecks in visual systems. As a result, new visual signal-processing areas have emerged such as light fields, ultra-high definition, - highframe rate and high dynamic range imaging. The novel combinations of those technologies can facilitate a hyper-realistic visual experience. This will without doubt be the future frontier for new imaging systems. However there are several - technological barriers that need to be overcome as well as challenges in what are the best solutions perceptually. The goal of this network is to combine expertise from several disciplines as engineering, computer science, physics, vision science and - psychology – usually disconnected – and train ESRs to be capable of working with all stages and aspects of visual processing to overcome existing interdisciplinary and intersectorial barriers to efficiently develop truly perceptually better visual - imaging systems. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Denmark - - - RealVision - - - H2020-MSCA-ITN-2017 - - - 765911 - - - - - POLITECNICO DI MILANO - UNIVERSITA DEGLI STUDI DI MILANO - LUNDS UNIVERSITET - UNIVERSIDAD DE ZARAGOZA - UNIVERSITAT POLITECNICA DE VALENCIA - KARLSRUHER INSTITUT FUER TECHNOLOGIE - MEDTRONIC BAKKEN RESEARCH CENTER B.V. - MORTARA INSTRUMENT EUROPE SRL - - - EUR 3 056 990,04 - - - MultidisciplinarY training network for ATrial fibRillation monItoring, treAtment and progression - - - EUR 3 056 990,04 - - - Italy - Italy - Sweden - Spain - Spain - Germany - Netherlands - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - MY-ATRIA brings together universities, companies and hospitals from 5 European countries (Italy, Spain, Sweden, Netherlands and Germany). The main scope of MY-ATRIA is to establish a multidisciplinary network able to develop - research and training “without walls” among academic, industrial and clinical entities in the area of cardiac, atrial disease. The composite nature of the MY_ATRIA network will ensure a highly qualified training and research infrastructure, which - meets the needs of academic research, industrial exploitation and clinical end-users. MY_ATRIA will generate a new profile of Researcher with an intersectoral expertise able to fill the existing gap between basic research and - clinical/businessoriented solutions. The training and research activities of MY-ATRIA are designed to pursue innovation in three domains: i) Educational concepts: MY_ATRIA will implement a new, intersectoral paradigm of PhD training to shape a modern - professional Researcher with cross-competencies and able to accelerate the transfer of advances in basic science to market and clinics. ii) Basic science: MY_ATRIA will gain new knowledge about atrial functioning, atrial arrhythmias development and - response to treatment, using multi-sectoral, model based integrative approach to explore the complex processes of electrical, contractile, and structural remodeling of the atrial myocardium. iii) Technology solutions: MY_ATRIA will develop new - methodologies and technologies for the early detection of atrial arrhythmias, its monitoring, progression and risk stratification as well as for a better patient treatment. - - 2021-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Italy - - - MY-ATRIA - - - H2020-MSCA-ITN-2017 - - - 766082 - - - - - Fundació Institut d'Investigació Biomèdica de Bellvitge - Academisch Medisch Centrum bij de Universiteit van Amsterdam - ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - VIB - TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY - MEDIZINISCHE UNIVERSITAET WIEN - IBM ISRAEL - SCIENCE AND TECHNOLOGY LTD - APPLIED RESEARCH USING OMIC SCIENCES SL - EVOTEC (FRANCE) SAS - - - EUR 3 831 957,72 - - - Targeting the metabolism-immune system connections in Cancer - - - EUR 3 831 957,72 - - - Spain - Netherlands - France - France - Belgium - Israel - Austria - Israel - Spain - France - - - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - "Cancer cells show common features of profound metabolic changes and escape from the immune system, independently of their tissue of origin. These metabolic adaptations are not limited to glucose metabolism (the ""Warburg - effect"") but are more general and affect several metabolic pathways in cancer cells as well as in the stroma, including immune cells. This network will explore how nutrients and hypoxia regulate the tumor-immune system interplay, and how this - communication is controlled by oncogenes, metabolic regulators and current or potential drugs targeting metabolism. - - - 2021-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Spain - - - META-CAN - - - H2020-MSCA-ITN-2017 - - - 766214 - - - - - UNIVERSITA DEGLI STUDI DI SALERNO - UNIVERSITA DEGLI STUDI DI CAGLIARI - UNIVERSITA DEGLI STUDI DI MILANO - UNIVERZITA PALACKEHO V OLOMOUCI - USTAV INFORMATIKY AV CR - USTAV TEORIE INFORMACE A AUTOMATIZACE AV CR VVI - TECHNISCHE UNIVERSITAET WIEN - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - UNIVERSITAT DE BARCELONA - UNIVERSITEIT VAN AMSTERDAM - UNIVERSITA DEGLI STUDI DELL'INSUBRIA - UNIVERSITAT AUTONOMA DE BARCELONA - UNIVERSITAET BERN - - - EUR 504 000 - - - Syntax Meets Semantics: Methods, Interactions, and Connections in Substructural logics. - - - EUR 580 500 - - - Italy - Italy - Italy - Czech Republic - Czech Republic - Czech Republic - Austria - Spain - Spain - Netherlands - Italy - Spain - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Substructural logics are formal reasoning systems that refine classical logic by weakening the structural rules in Gentzen sequent calculus. - - 2019-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Italy - - - SYSMICS - - - H2020-MSCA-RISE-2015 - - - 689176 - - - - - THE UNIVERSITY OF SHEFFIELD - TTY-SAATIO - ASOCIACION CENTRO TECNOLOGICO CEIT-IK4 - UNIVERSITY OF BEDFORDSHIRE - INNOLAS LASER GMBH - - - EUR 3 208 740 - - - Nanoscale self-assembled epitaxial nucleation controlled by interference lithography - - - EUR 3 208 740 - - - United Kingdom - Finland - Spain - United Kingdom - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - By overcoming all the limitations of conventional top-down nanostructuring, the NanoStencil project seeks to initiate a new process paradigm for the production of dense arrays of identical nanostructures of precise size, shape - and composition. It achieves this by combining the simplicity of structuring with light, with the advantages of molecular self-assembly, to provide a single step, cost effective and state of the art capability for next-generation ordered arrays of - nanostructures. New methods to achieve such structures are a vital requirement for the exploitation of devices in the quantum regime. In our approach, laser interference patterning is applied by means of ultrashort pulses to material surfaces at the - nanostructure formation phase, where it acts to modify local reaction processes providing energetically favourable sites for the nucleation of self-assembly. The approach is based on some established principles and prior art gained within the - consortium, but is yet to be demonstrated at the device scale. - - 2020-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-01-2016-2017 - FET-Open research and innovation actions - - - RIA - Research and Innovation action - - - United Kingdom - - - NanoStencil - - - H2020-FETOPEN-1-2016-2017 - - - 767285 - - - - - DANMARKS TEKNISKE UNIVERSITET - KOBENHAVNS UNIVERSITET - UNIVERSITEIT ANTWERPEN - ACCENT PRO 2000 s.r.l. - STICHTING CENTRUM VOOR WISKUNDE EN INFORMATICA - PAUL SCHERRER INSTITUT - BUNDESANSTALT FUER MATERIALFORSCHUNG UND -PRUEFUNG - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - LUNDS UNIVERSITET - THE UNIVERSITY OF MANCHESTER - OCV CHAMBERY INTERNATIONAL - - - EUR 3 999 114 - - - MUltiscale, Multimodal and Multidimensional imaging for EngineeRING - - - EUR 3 999 114 - - - Denmark - Denmark - Belgium - Romania - Netherlands - Switzerland - Germany - France - Sweden - United Kingdom - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The overarching goal of MUMMERING is to create a research tool that encompasses the wealth of new 3D imaging mo-dalities that are surging forward for applications in materials engineering, and to create a doctoral programme - that trains 15 early stage researchers (ESRs) in this tool. This is urgently needed to prevent that massive amounts of valuable tomogra-phy data ends on a virtual scrapheap. The challenge of handling and analysing terabytes of 3D data is already - limiting the level of scientific insight that is extracted from many data sets. With faster acquisition times and multidimensional modali-ties, these challenges will soon scale to the petabyte regime. To meet this challenge, we will create an open - access, open source platform that transparently and efficiently handles the complete workflow from data acquisition, over reconstruction and segmentation to physical modelling, including temporal models, i.e. 3D “movies”. We consider it essential to - reach this final step without compromising scientific standards if 3D imaging is to become a pervasive research tool in the visions for Industry 4.0. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Denmark - - - MUMMERING - - - H2020-MSCA-ITN-2017 - - - 765604 - - - - - THE UNIVERSITY OF BIRMINGHAM - UNIVERSITY OF LEICESTER - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSIDAD COMPLUTENSE DE MADRID - UNIVERSITEIT VAN AMSTERDAM - WAGENINGEN UNIVERSITY - KARLSRUHER INSTITUT FUER TECHNOLOGIE - LEIBNIZ - INSTITUT FUER PFLANZENGENETIK UND KULTURPFLANZENFORSCHUNG - UNIVERSITAET HAMBURG - UNIVERSITAT WIEN - - - EUR 3 107 819,88 - - - Meiotic Control of Recombination in Crops - - - EUR 3 107 819,88 - - - United Kingdom - United Kingdom - United Kingdom - France - France - Spain - Netherlands - Netherlands - Germany - Germany - Germany - Austria - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The increasing growth of human population and the intrinsic increase in world pollution, together with the uncertain challenge of climate change will undeniably require an internationally sustained effort to meet the global - food demand. An increase of food production by at least 50% has been projected to be necessary by 2050. Thus, Food Security is one of the most important challenges for the future. Classical plant breeding has been crucial to improve our crop species - from the beginning of human civilizations until now. Classical plant breeding harnesses the natural genetic variation that is generated by meiotic recombination. During meiosis, new allele combinations are obtained which could confer new improved - phenotypes. Nevertheless, plant breeders are reaching the limits of this methodology. These boundaries are intrinsically shaped by the restrictions on the frequency and distribution of meiotic recombination in the different crop species. In cereals, - it has been estimated that 30-50% of genes rarely (if at all) recombine, limiting the genetic variation available to use by plant breeders. The MEICOM consortium has been designed to prepare future scientists, academics, plant breeders and policy - makers in how to manipulate and control meiotic recombination in different crops (brassicas, wheats, barley, tomato, maize) and to provide a sustainable assurance on Food Security for the future. MEICOM is a network of the finest European Plant - Meiosis Researchers with internationally acclaimed industrial partners to gain knowledge and transfer it into our training programme and the general public. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - MEICOM - - - H2020-MSCA-ITN-2017 - - - 765212 - - - - - TECHNISCHE UNIVERSITAET DRESDEN - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - UNIVERSITAET GRAZ - UNIVERSITE DE LIEGE - THE UNIVERSITY OF MANCHESTER - - - EUR 3 997 843,75 - - - Mechanics with Molecules - - - EUR 3 997 843,75 - - - Germany - France - Spain - Austria - Belgium - United Kingdom - - - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In this project, single molecule-machines will be constructed and tested on a surface and one at a time, controlling the rotation and the work delivered by a single molecule-motor directly at the atomic scale. The molecule - motors and gears, designed and tested by MEMO, will be further adapted to applications requiring collective and synchronous motion. - - - 2021-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-01-2016-2017 - FET-Open research and innovation actions - - - RIA - Research and Innovation action - - - Germany - - - MEMO - - - H2020-FETOPEN-1-2016-2017 - - - 766864 - - - - - UNIVERSITA DEGLI STUDI DI UDINE - Eidgenössische Technische Hochschule Zürich - TECHNISCHE UNIVERSITEIT DELFT - ISTANBUL TEKNIK UNIVERSITESI - UNIVERSITAT AUTONOMA DE BARCELONA - MAGNES AG - RISE RESEARCH INSTITUTES OF SWEDEN AB - INSTITUT JOZEF STEFAN - VRIJE UNIVERSITEIT BRUSSEL - UNIVERSITATEA POLITEHNICA DIN BUCURESTI - AKADEMIA GORNICZO-HUTNICZA IM. STANISLAWA STASZICA W KRAKOWIE - TEKNISKA HOGSKOLAN I JONKOPING AB - INEB-INSTITUTO NACIONAL DE ENGENHARIA BIOMEDICA - ELSYCA NV - LIMACORPORATE SPA - - - EUR 3 726 379,44 - - - Advanced integrative solutions to Corrosion problems beyond micro–scale: towards long-termdurability of miniaturized Biomedical, Electronic and Energy systems - - - EUR 3 726 379,44 - - - Italy - Switzerland - Netherlands - Turkey - Spain - Switzerland - Sweden - Slovenia - Belgium - Romania - Poland - Sweden - Portugal - Belgium - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - mCBEEs Innovative Training Network is a joint venture between academy and industry with a primary goal to train young researchers in the field of corrosion and corrosion protection of micro- and nanodevices. The network - focuses on the study of corrosion mechanisms beyond microscale of components in miniaturized systems in different environments using localized techniques, and the development of multifunctional protective coatings to increase the long-term durability - of such components. Corrosion phenomena occurring in micro- and nanodimensional components can develop in a completely different path than in their bulk counterparts and corrosion might influence the functional properties of small components in a - much more severe manner. Three main strategic fields where corrosion could seriously compromise the performance of micro- or nanodevices have been identified: biotechnology (micro/nano-robotic implants, micro/nano-electrodes for recording and - stimulating neuronal activity, or micro-featured prosthesis implants); electronics (micro/nano-components in electronic boards, magnetooptical thin films, multiferroic micro/nano-devices); and energy technology (metallic foam-based micro- and - nanostructured electrodes, self-standing nanoarchitectures). Several disciplines (physics, electrochemistry, engineering, biology and robotics) converge to provide a multidisciplinary approach to accomplish mCBEEs goals. The ITN brings together 15 - beneficiaries and 3 partners including 4 research institutes and 4 private companies belonging to 9 EU Member states, and to 2 associated states (Switzerland, Turkey). The Consortium complementarity will enable a high-level, multifaceted educational - programme, where specials efforts will be done to bridge fundamental research with industrial applications. The educational programme is integrated with training in soft skills and aims at providing a network of highly qualified researchers able to - tackle challenges both in Academia and Industry. - - 2021-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Italy - - - mCBEEs - - - H2020-MSCA-ITN-2017 - - - 764977 - - - - - POLITECNICO DI MILANO - UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA - UNIVERSITY OF GLASGOW - PHILIPPS UNIVERSITAET MARBURG - TECHNISCHE UNIVERSITAET DRESDEN - MICRO PHOTON DEVICES S.R.L. - - - EUR 3 106 381 - - - micro-crystals Single Photon InfraREd detectors - - - EUR 3 106 381,25 - - - Italy - Italy - United Kingdom - Germany - Germany - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - µSPIRE aims at establishing a technological platform for homo- and hetero- structure based photonic and electronic devices using the self-assembling of epitaxial crystals on patterned Si substrates. - - 2020-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-01-2016-2017 - FET-Open research and innovation actions - - - RIA - Research and Innovation action - - - Italy - - - microSPIRE - - - H2020-FETOPEN-1-2016-2017 - - - 766955 - - - - - ASTON UNIVERSITY - MIMETAS BV - ST GEORGE'S HOSPITAL MEDICAL SCHOOL - UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK - UNIVERSITA DEGLI STUDI DI TORINO - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - UNIVERSITAET ROSTOCK - FUNDACION PARA LA INVESTIGACION DEL HOSPITAL UNIVERSITARIO LA FE DE LA COMUNIDAD VALENCIANA - KATHOLIEKE UNIVERSITEIT LEUVEN - UNIVERSITEIT MAASTRICHT - - - EUR 3 929 698,80 - - - Innovation in modelling Placenta for Maternal and Fetal Health - - - EUR 3 929 698,80 - - - United Kingdom - Netherlands - United Kingdom - Ireland - Italy - France - Germany - Spain - Belgium - Netherlands - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - “The placenta is the least understood human organ but arguably one of the most important”-NIH Human Placenta Project . Innovation in Modelling Placenta for Maternal and Fetal Health (iPLACENTA) is a European Training Network - (ETN), and will act as a springboard for promoting international, intersectoral and multi/inter-disciplinary training, career development and collaboration of fifteen early-stage researchers (ESRs) in Maternal and Fetal Health. iPLACENTA will improve - our ability to study, model and visualise the placenta. iPLACENTA focuses on doctoral-level training and will be delivered by eleven participating universities located in ten different European countries. It coordinates research and training - collaboration among world-leading academic institutions in Europe, providing a new combination of in-depth international expertise. iPLACENTA’s unique network aims are to improve our ability to study the placenta through in vitro and mathematical - modelling (WP1&2). Whilst enhancing visualisation and assessment of the placenta in animal models and the clinic, thus enhancing investigation and prognosis of complicated pregnancies. To link the research to industrial exploitation, the network - brings together four different businesses; two established companies as beneficiaries Mimetas (MIM) (organ-on-a-chip developer) and Moor, a clinical-technology specialist, together with two partners that are industrial global brands Samsung (SAM) and - FujifFilm VisualSonics (FUJ). Together they will work with academics and clinicians to develop new placenta-on-a-chip technology (WP1), in silico placenta modelling (WP2), new modalities of laser technology to visualise the placenta in vivo (WP3), - improve maternal-cardiovascular assessment and validate novel ultrasound tools for diagnosis of complicated pregnancies (WP3). Cross-sectorial training delivered by Business and Law Schools, Industry, Clinical specialist and European leaders in - OpenScience-OpenInnovation. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - iPLACENTA - - - H2020-MSCA-ITN-2017 - - - 765274 - - - - - CHALMERS TEKNISKA HOEGSKOLA AB - NPL MANAGEMENT LIMITED - LATVIJAS UNIVERSITATE - UNIVERSITY OF SURREY - BEN-GURION UNIVERSITY OF THE NEGEV - - - EUR 2 991 978,75 - - - High Frequency Topological Insulator devices for Metrology - - - EUR 2 991 978,75 - - - Sweden - United Kingdom - Latvia - United Kingdom - Israel - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In this project we will study and exploit the properties of 3D topological insulator (TI) materials incorporated into high frequency devices. The main driver of the project is the prospect of using a TI nanoribbon to create a - topologically protected single-electron charge pump that can be used as a metrological quantum current standard, or in other words to lay the technological foundations for a TI-based device that can realize the SI Ampere. An accurate charge pump that - can operate at temperatures and magnetic fields achievable using affordable table-top systems would be of immediate use in the realization of the Ampere. The technological development in this project will lay the groundwork or charge pumping in TI - nanoribbons, as well as for other devices that exploit the unique properties of TI for high-frequency applications including sensing, precision measurement and topologically protected quantum computation. - - - 2022-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-01-2016-2017 - FET-Open research and innovation actions - - - RIA - Research and Innovation action - - - Sweden - - - HiTIMe - - - H2020-FETOPEN-1-2016-2017 - - - 766714 - - - - - UNIVERSITA DEGLI STUDI ROMA TRE - UNIVERSITY OF GLASGOW - IHP GMBH - INNOVATIONS FOR HIGH PERFORMANCE MICROELECTRONICS/LEIBNIZ-INSTITUT FUER INNOVATIVE MIKROELEKTRONIK - Eidgenössische Technische Hochschule Zürich - NEXTNANO GMBH - - - EUR 3 206 498,75 - - - Far-infrared Lasers Assembled using Silicon Heterostructures - - - EUR 3 206 498,75 - - - Italy - United Kingdom - Germany - Switzerland - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The THz part of the electromagnetic spectrum (0.3-10 THz) is currently exploited in commercial security screening systems (weapon detection beneath clothes), medical diagnostics tools (skin and breast cancer, burns, and in - ophthalmology) and production-line monitoring (non-destructive test in the pharmaceutical industry). Existing sources of THz radiation are still too large and expensive to be a massively deployed in all of the existing and proposed applications, - which include large bandwidth wireless communications and the extension of security screening to far-infrared spectroscopic identification of chemicals and explosives up to 10 THz. A lower production cost, a higher level of integration with control - electronics, and a broader range of emitted wavelength are all desirable to expand the application of THz radiation. - - 2020-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-01-2016-2017 - FET-Open research and innovation actions - - - RIA - Research and Innovation action - - - Italy - - - FLASH - - - H2020-FETOPEN-1-2016-2017 - - - 766719 - - - - - CONSIGLIO NAZIONALE DELLE RICERCHE - THE TRUSTEES OF BOSTON UNIVERSITY - INSTITUT CURIE - REGION NORDJYLLAND (NORTH DENMARK REGION) - FLUIGENT SA - HANSABIOMED LIFE SCIENCES OU - - - EUR 2 982 275 - - - Integrated nanoparticle isolation and detection system for complete on-chip analysis of exosomes - - - EUR 2 983 525 - - - Italy - United States - France - Denmark - France - Estonia - - - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The aim of Project INDEX is to isolate and characterize nanoparticles available in bodily fluids through development and integration of novel technological breakthroughs. The technology will enable the analysis of clinically - valuable nanoparticles called exosomes towards new generation diagnostics. Exosomes are known to mediate communication between cells and their effective utilization holds a great promise of revolutionizing the standard of clinical care. However, - their detection and molecular profiling is technically challenging. The proposed technology will isolate exosomes that are as small as 30nm in diameter from human plasma with high purity, and provide in-depth, multi-parameter characterization of the - particles through digital counting, size determination, and biological phenotyping. - - - 2020-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-01-2016-2017 - FET-Open research and innovation actions - - - RIA - Research and Innovation action - - - Italy - - - INDEX - - - H2020-FETOPEN-1-2016-2017 - - - 766466 - - - - - UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK - - - EUR 187 866 - - - Exploring gender equality in Irish higher education: Qualitative case-study research into the response to, and process of Athena SWAN - - - EUR 187 866 - - - Ireland - - - Higher or Secondary Education Establishments - - It has been shown that gender equality interventions in the higher education sector are vital in addressing career advancement challenges facing female academics and researchers, in particular the higher up the career ladder - researchers progress. This proposed research would explore a gender equality intervention, Athena SWAN, which seeks to encourage commitment to advancing the careers of women in science. It has been shown that barriers to career advancement are mainly - due to institutional factors, rather than individual ones, such as career drive or skill. Strengthening research and innovation in Europe, with respect to encouraging gender diversity to support science excellence and relevance, is an identified - priority of Horizon 2020. This proposed study would explore the response to, and processes of, the Athena SWAN programme in one European country, Ireland. With a number of EC funded projects in Europe, and research growing, the time is ripe for - conducting this research and informing the developing theoretical and policy context for gender equality in higher education in Europe. Athena SWAN is a new intervention in Ireland (since 2015) and this novelty in the process, alongside the context - of change within institutions, would elicit a wealth of qualitative data findings that would be generalisable across European institutions. Given my expertise in qualitative research methods and participation in a FP7 gender equality project, I am in - the best position to restart my career in this field of inquiry, within a highly stimulating and renowned social science research environment. Supporting this original research would result in a wealth of useful findings for peer researchers, the - policy sector and the wider research and innovation community in Europe, as well as engaging with the public. I would seek to promote the Fellowship with a zeal reflecting the sentiment of the extraordinary woman in science who inspired this - programme, Dr. Marie Skłodowska-Curie. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - Ireland - - - GendeResearchIreland - - - H2020-MSCA-IF-2016 - - - 750408 - - - - - UNIVERSITY OF SURREY - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA - TECHNISCHE UNIVERSITAET WIEN - HEIDELBERGCEMENT AG - - - EUR 3 415 255,56 - - - Engineered Calcium-Silicate-Hydrates for Applications - - - EUR 3 415 255,56 - - - United Kingdom - Switzerland - Italy - Austria - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - ERICA stands for engineered calcium-silicate-hydrates for applications. Inorganic hydrates, such as C-S-H, are used in applications from construction to dentistry. In every case, there is need to optimise the hydrate - properties for the application. More reactive cements are needed to lower the CO2 impact of construction. Dentistry needs improved mechanical stability. The traditional way to improve hydrates is by trial and error. This is ineffective. ERICA offers - a transformative materials science approach based on gaining detailed understanding the associated nanoscience. ERICA seeks coherent understanding and control of hydrate nucleation and growth as a means to control properties; of the first water - sorption cycle when hydrates undergo structural change the consequences of which for performance are only just becoming apparent; and of water transport in hydrates that severely impacts degradation. To do this ERICA exploits recent developments in - understanding of hydrate chemistry, in 1H NMR relaxometry and in numerical modeling. Success with ERICA will (i) give industry ways to target design hydrates; (ii) create numerical software tools to model hydrate performance; and (iii) leave good - practice and know-how to adopt emergent methods. ERICA trains 13 multi-disciplinary researchers: ESRs ready to find employment with cement product manufacturers, instrumentation manufacturers, in numerical modeling and in academia. This cohort is - much needed by industry. The ESRs receive comprehensive academic and transferable skills training comprised of residential schools, workshops, peer learning and industry secondments. Training and dissemination are delivered in collaboration with the - industry-academic cement science network: NANOCEM. Courses will be made into MOOCs. ERICA is led by 4 universities and an international cement manufacturer. It is supported by 5 Partner companies. - - 2021-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - ERICA - - - H2020-MSCA-ITN-2017 - - - 764691 - - - - - ATHINA-EREVNITIKO KENTRO KAINOTOMIAS STIS TECHNOLOGIES TIS PLIROFOFORIAS, TON EPIKOLNONION KAI TIS GNOSIS - THE UNIVERSITY OF MANCHESTER - TECHNISCHE UNIVERSITAT DARMSTADT - INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE - EUROPEAN MOLECULAR BIOLOGY LABORATORY - AGROKNOW IKE - STICHTING LIBER - UNIVERSITEIT VAN AMSTERDAM - THE OPEN UNIVERSITY - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - FUNDACION CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III - THE UNIVERSITY OF SHEFFIELD - GESIS-LEIBNIZ-INSTITUT FUR SOZIALWISSENSCHAFTEN EV - ETHNIKO DIKTYO EREVNAS TECHNOLOGIAS AE - FRONTIERS MEDIA SA - THE UNIVERSITY OF STIRLING - UNIVERSITY OF GLASGOW - BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION - - - EUR 5 375 535,50 - - - Open Mining INfrastructure for TExt and Data - - - EUR 6 068 072,50 - - - Greece - United Kingdom - Germany - France - Germany - Greece - Netherlands - Netherlands - United Kingdom - Switzerland - Spain - United Kingdom - Germany - Greece - Switzerland - United Kingdom - United Kingdom - Spain - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - Recent years witness an upsurge in the quantities of digital research data, offering new insights and opportunities for improved understanding. Text and data mining is emerging as a powerful tool for harnessing the power of - structured and unstructured content and data, by analysing them at multiple levels and in several dimensions to discover hidden and new knowledge. However, text mining solutions are not easy to discover and use, nor are they easily combinable by end - users. OpenMinTeD aspires to enable the creation of an infrastructure that fosters and facilitates the use of text mining technologies in the scientific publications world, builds on existing text mining tools and platforms, and renders them - discoverable and interoperablethrough appropriate registriesand a standards-based interoperability layer, respectively. It supports training of text mining users and developers alike and demonstrates the merits of the approach through several use - cases identified by scholars and experts from different scientific areas, ranging from generic scholarly communication to literaturerelated tolife sciences, food and agriculture, and social sciences and humanities. Through its infrastructural - activities, OpenMinTeD’s vision is tomake operational a virtuous cycle in which a) primary content is accessed through standardised interfaces and access rules b) by well-documented and easily discoverable text mining services that process, analyse, - and annotate text c) to identify patterns and extract new meaningful actionable knowledge, which will be used d) for structuring, indexing, and searching content and, in tandem, e) acting as new knowledge useful to draw new relations between content - items and firing a new mining cycle. To achieve its goals, OpenMinTeD brings together different stakeholders, content providers and scientific communities, text mining and infrastructure builders, legal experts, data and computing centres, industrial - players, and SMEs. - - 2018-05-31, ongoing project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.3."> - - - EINFRA-1-2014 - Managing, preserving and computing with big research data - - - RIA - Research and Innovation action - - - Greece - - - OpenMinTeD - - - H2020-EINFRA-2014-2 - - - 654021 - - - - - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - DANMARKS TEKNISKE UNIVERSITET - QUANTUMWISE A/S - UNIVERSITE PARIS DIDEROT - PARIS 7 - CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL - UNIVERSITAT DE VALENCIA - - - EUR 3 894 248,70 - - - Concepts and tools in molecular spintronics - - - EUR 3 894 248,70 - - - France - Denmark - Denmark - France - Germany - Spain - - - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Molecular spintronics is an emergent field combining the flexibility of molecular electronics and and molecular magnetism with the advantages of spintronics. Its main goal is the manipulation of the electron spin by a wise - combination of ad-hoc molecules and inorganic substrate. Besides the rich magnetic behavior resulting from the interaction between a magnetic molecule and a metal surface, or vice versa, additional functions such as switchability by external - parameters (light, voltage) can be integrated. This multi-disciplinary field offers a wide range of routes towards spin-based devices with potential technological applications in information storage and processing However, due to the very large - number of possible material combinations there is an urgent need for fundamental understanding, guiding concepts and tools to scale up and systematize the search of new smart functional molecular designs. Our scientific target is to develop a - modelling platform around molecular spintronics that is essential to stimulate fundamental as well as applied/technological research and facilitate the emergence of new key enabling technologies. - - 2021-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-01-2016-2017 - FET-Open research and innovation actions - - - RIA - Research and Innovation action - - - France - - - COSMICS - - - H2020-FETOPEN-1-2016-2017 - - - 766726 - - - - - Teknologian tutkimuskeskus VTT Oy - CARL VON OSSIETZKY UNIVERSITAET OLDENBURG - UNIVERSITY OF DURHAM - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - IBM RESEARCH GMBH - - - EUR 2 919 037,50 - - - Energy Filtering Non-Equilibrium Devices - - - EUR 2 919 037,50 - - - Finland - Germany - United Kingdom - France - Switzerland - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - This project aims for revolutionary energy filtering nano-devices for information and communications technology (ICT). It is at the intersection of phononics, photonics, nanoscale electro-thermal devices and molecular - engineering. By building new energy filtering devices down to molecular scales we aim to generate new knowledge and understanding of the electronic, phononic and near-field energy/heat fluxes at the fundamental limits of nano-scale energy management, - and to demonstrate novel proof-of-concept non-equilibrium phonon engineered electro-thermal devices in real applications. The efficient nano-scale thermal management necessitate developing new theoretical and experimental tools for understanding and - mastering the individual non-equilibrium energy/particle channels and inter-channel couplings. Control of the physical mechanisms behind non-equilibrium electronic energy filtering effects will be firstly addressed by non-linear transport in - molecular junctions by developing new research tools that combine state-of-the-art molecular synthesis, bolometers, scanning probe microscopy technologies and theoretical modelling. In parallel with the molecular bottom-up approach, we will work with - scalable thermionic nano-junctions, which not only have great technological potential of their own but also serve as a model system for the molecular devices. By employing non-linear out of equilibrium electro-thermal effects in molecular and - scaled-down junction systems, we pursue the realization of proof-of-concept ICT devices utilizing these technologies within the time span of the project. This project will combine synergies in theory, experiment and technology-development covering - different fields from chemistry to electronics. The project partners, who are leaders in their respective fields, form a consortium that is uniquely positioned to achieve the ambitious objectives. - - 2021-06-30, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-01-2016-2017 - FET-Open research and innovation actions - - - RIA - Research and Innovation action - - - Finland - - - EFINED - - - H2020-FETOPEN-1-2016-2017 - - - 766853 - - - - - THE UNIVERSITY OF BIRMINGHAM - UNIVERSITEIT LEIDEN - Honda Research Institute Europe GmbH - NEC EUROPE LTD - - - EUR 2 060 348,04 - - - Experience-based Computation: Learning to Optimise - - - EUR 2 060 348,04 - - - United Kingdom - Netherlands - Germany - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The overall theme of our proposed doctoral programme is ECOLE: Experience-based COmputation: Learning to optimisE. It seeks novel synergies between nature inspired optimisation and machine learning to address new challenges - that arise in industry due to the increasing complexity of products, product development and production processes. The unique aspect of ECOLE is to study and capture the notion of experience that is associated with expert engineers, who have worked - on complex optimisation tasks for a certain time, in a computational framework composed of machine learning and optimisation strategies. We aim at developing cutting-edge optimisation algorithms that can continuously accumulate experience by learning - from development projects both over time and across different problem categories. The more such algorithms are used for different optimisation problems, the better they become since their accumulated experience increases. The Consortium consists of - two world-leading universities, the University of Birmingham (UK) and the University of Leiden (The Netherlands), both in the top 150 in the 2016-17 Times Higher Education World University Rankings, and two innovative companies, Honda Research - Institute Europe GmbH (Germany) in the automotive sector and NEC Europe Ltd (UK) in the ICT sector. All have world-leading research groups with complementary expertise that support ECOLE. ECOLE fills an urgent need in Europe for highly skilled - optimisation and machine learning experts who have first-hand industrial experiences allowing sustainable know-how growth for solving future challenges. Its entire training programme is centred around a set of novel research projects proposed for - early stage researchers (ESRs), complemented by domain knowledge training, hands-on engineering training and transferable skill training. ESRs will spend 50% of their time in the non-academic beneficiaries and be trained in different academic - environments and industrial sectors. - - 2022-03-31, Grant Agreement signed - - - 2018-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-EID - European Industrial Doctorates - - - United Kingdom - - - ECOLE - - - H2020-MSCA-ITN-2017 - - - 766186 - - - - - UNIVERSITAETSKLINIKUM AACHEN - IDRYMA IATROVIOLOGIKON EREUNON AKADEMIAS ATHINON - MOSAIQUES DIAGNOSTICS GMBH - MEDIZINISCHE UNIVERSITAET WIEN - RD NEPHROLOGIE SAS - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - UNIVERSITEIT MAASTRICHT - KAROLINSKA INSTITUTET - DSM R & D SOLUTIONS BV - - - EUR 2 795 346 - - - Combatting the CardioRenal Syndrome: towards an integrative Analysis to reduce cardiovascular burden in chronic kidney disease - - - EUR 2 795 346 - - - Germany - Greece - Germany - Austria - France - France - Netherlands - Sweden - Netherlands - - - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Successfully combatting a complex disease requires multi-disciplinary and methodically well-trained scientists. CaReSyAn strives to accomplish exactly this: we will train scientists to successfully integrate proteomics, - clinical, experimental and bioinformatical analyses to enhance the understanding, diagnosis and therapy of the cardiorenal syndrome (CRS). CRS comprises disorders of the heart, vessels and kidneys, including the increased development of - cardiovascular disease (CVD) in patients with chronic kidney disease (CKD). With ~45% of all deaths in CKD patients caused by CVD, the socio-economic burden of CRS is extremely high. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - CaReSyAn - - - H2020-MSCA-ITN-2017 - - - 764474 - - - - - JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH - PAUL SCHERRER INSTITUT - HELSINGIN YLIOPISTO - UNIVERSITY OF LEEDS - LEIBNIZ INSTITUT FUER TROPOSPHAERENFORSCHUNG e.V. - IONICON ANALYTIK GMBH - UNIVERSITAT WIEN - KARLSRUHER INSTITUT FUER TECHNOLOGIE - TOFWERK AG - - - EUR 3 919 734,36 - - - CLOUD-MObility, Training and InnOvation Network - - - EUR 3 919 734,36 - - - Germany - Switzerland - Switzerland - Finland - United Kingdom - Germany - Austria - Austria - Germany - Switzerland - - - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The aim of CLOUD-MOTION is to establish a network of early stage researchers (ESRs, all PhD students) at 10 institutions across Europe. The role of aerosol nucleation and ice nucleation for atmospheric aerosol, clouds and climate is investigated. - - 2021-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - CLOUD-MOTION - - - H2020-MSCA-ITN-2017 - - - 764991 - - - - - AARHUS UNIVERSITET - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - VIB - UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK - BIOMODICS APS - HUMBOLDT-UNIVERSITAET ZU BERLIN - SPINVERSE OY - Universidade Federal do Pará - - - EUR 3 787 932,50 - - - in vivo optogeneticS, elecTrophysiology and phArmacology with an ultRasonically-powered DUST for Parkinson's Disease - - - EUR 3 803 057,50 - - - Denmark - Germany - France - Belgium - Ireland - Denmark - Germany - Finland - Brazil - - - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - The main goal of the STARDUST project is to realize a novel wireless implantable and independent micro-scale device (200x200x200 µm3) enabling in-vivo electrophysiology, optogenetics and ultra-localized drug delivery in freely - moving animals. The device will be used to target specific neural circuits of the brain and test a new therapeutic approach for Parkinson’s Disease (PD). - - - 2021-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-01-2016-2017 - FET-Open research and innovation actions - - - RIA - Research and Innovation action - - - Denmark - - - STARDUST - - - H2020-FETOPEN-1-2016-2017 - - - 767092 - - - - - UNIVERSITE DE LIEGE - THE HEBREW UNIVERSITY OF JERUSALEM - UNIVERSITA DEGLI STUDI DI PADOVA - CONSIGLIO NAZIONALE DELLE RICERCHE - KILOLAMBDA TECHNOLOGIES LTD - PROBAYES SAS - - - EUR 2 993 640 - - - Coherent Optical Parallel Computing - - - EUR 2 993 640 - - - Belgium - Israel - Italy - Italy - Israel - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - COPAC is a transformative novel area in computing both because of the technology, coherent information transfer by ultrafast laser addressing of engineered quantum dots, QD, arrays and because of the specialized parallel - processing of large amounts of information. We will make foundational experimental, theoretical and algorithmic innovations to demonstrate a new technological paradigm for ultrafast parallel multi-valued information processing. We aim to develop a - ground-breaking nonlinear coherent spectroscopy combining optical addressing and spatially macroscopically resolved optical readout to achieve unprecedented levels of speed, density and complexity. Two key high-risk / high-reward pioneering elements - are the quantum engineered coherent concatenation of units and the multidirectional optical detection. Experimental demonstrations on tailored multilayer QD arrays of increasing complexity, integration into a device and novel hardware and matched - compilers will be delivered. Preliminary experimental demonstrations of the response of solutions and of QD films are available as is the validation of logic operation in parallel. - - 2020-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-01-2016-2017 - FET-Open research and innovation actions - - - RIA - Research and Innovation action - - - Belgium - - - COPAC - - - H2020-FETOPEN-1-2016-2017 - - - 766563 - - - - - FYZIKALNI USTAV AV CR V.V.I - THE UNIVERSITY OF NOTTINGHAM - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - CENTRO DE CALCULO IGS SOFTWARE SOCIEDAD LIMITADA - UNIVERZITA KARLOVA - JOHANNES GUTENBERG-UNIVERSITAT MAINZ - - - EUR 3 682 973,75 - - - Antiferromagntic spintronics - - - EUR 3 682 973,75 - - - Czech Republic - United Kingdom - Germany - Spain - Czech Republic - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The aim of the project is to open and explore a new research avenue, with emerging and future information technologies at its horizon, where antiferromagnets take the center stage. Antiferromagnets and ferromagnets represent - two fundamental forms of magnetism with antiferromagnets being the more abundant of the two. However, it has been notoriously difficult to manipulate and detect antiferromagnets by any practical means due to their compensated magnetic moment. This - has left antiferromagnets over their hundred-year history virtually unexploited and only poorly explored, in striking contrast to the thousands of years of fascination and utility of ferromagnets. The project builds on our very recent discovery of a - new relativistic spin-torque phenomenon that allow us to efficiently control antiferromagnetic moments in spintronic devices and by this to unlock a multitude of known and newly identified unique features of this “dormant-giant” class of materials. - We propose to explore three intertwined research areas in order to scientifically establish: (i) The concept of antiferromagnetic memory-logic suitable for the development of future “Beyond Moore” information technologies. (ii) The concept of - antiferromagnetic memory-logic components responding to pulses of lengths downscaled by twelve orders of magnitude from seconds to picoseconds. (iii) The concept in which antiferromagnets provide a unifying platform for realizing synergies among - three prominent fields of contemporary condensed matter physics, namely spintronics, Dirac quasiparticles, and topological phases. Our very recent achievements, including the demonstration of a USB proof-of-concept antiferromagnetic memory, make - Europe a birthplace of the emerging field of antiferromagnetic spintronics. To contribute in a decisive way that the future science and technology impact of the field remains in Europe, we bring together a critical mass of seven academic and a SME - partner covering all the necessary skills. - - 2021-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-01-2016-2017 - FET-Open research and innovation actions - - - RIA - Research and Innovation action - - - Czech Republic - - - ASPIN - - - H2020-FETOPEN-1-2016-2017 - - - 766566 - - - - - UNIVERSITY OF PLYMOUTH - UNIVERSITY COLLEGE LONDON - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - STOCKHOLMS UNIVERSITET - KAROLINSKA INSTITUTET - ISTITUTI FISIOTERAPICI OSPITALIERI - UNIVERSITA DEGLI STUDI DI CATANIA - SCRIBA NANOTECNOLOGIE SRL - MEDICAL TRIALS ANALYSIS ITALY SRL - The Hyve B.V. - STICHTING KATHOLIEKE UNIVERSITEIT - KATHOLIEKE UNIVERSITEIT LEUVEN - - - EUR 3 687 311,88 - - - An Integrated Platform for Developing Brain Cancer Diagnostic Techniques - - - EUR 3 687 311,88 - - - United Kingdom - United Kingdom - United Kingdom - Sweden - Sweden - Italy - Italy - Italy - Italy - Netherlands - Netherlands - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The mission of AiPBAND is to train a new generation of entrepreneurial and innovative early-stage researchers (ESRs) in the early diagnosis of brain tumours using molecular biomarkers in the blood, meeting the medical and - societal challenges of this emerging field. AiPBAND will focus on gliomas, a range of devastating and progressive brain tumours affecting around 25,000 people each year in Europe and responsible for the majority of deaths from primary brain tumours. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - AiPBAND - - - H2020-MSCA-ITN-2017 - - - 764281 - - - - - UNIVERSITA DEGLI STUDI DI TORINO - UNIVERSITA DEGLI STUDI DEL PIEMONTE ORIENTALE AMEDEO AVOGADRO - AALBORG UNIVERSITET - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - ECOLE POLYTECHNIQUE - KARADENIZ TEKNIK UNIVERSITESI - LIQTECH INTERNATIONAL A/S - Società Metropolitana Acque Torino S.p.A. - CENTRO DE INVESTIGACIONES ENERGETICAS, MEDIOAMBIENTALES Y TECNOLOGICAS-CIEMAT - PANEPISTIMIO IOANNINON - UNIVERSITAT POLITECNICA DE VALENCIA - - - EUR 3 897 678,24 - - - Interdisciplinar cross-sectoral approach to effectively address the removal of contaminants of emerging concern from water - - - EUR 3 897 678,24 - - - Italy - Italy - Denmark - France - France - Turkey - Denmark - Italy - Spain - Greece - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - AQUAlity is a multidisciplinary and cross-sectoral European Training Network, that consist in eighteen participants (7 universities, 3 research institutes and 8 companies) and aims to generate and promote highly skilled - scientists with the potential to face the present and future challenges concerning the protection of water resources from contaminants of emerging concern (CECs). AQUAlity will enroll fifteen early-stage researchers (ESRs) to conduct cutting-edge - research on multidisciplinary aspects of novel hybrid technologies for the removal of CECs from aqueous systems. Moreover, ESRs will be trained to develop their creativity, critical and autonomous thinking, and entrepreneurial skills, thus boosting - their scientific skills and innovation capacity in the field of water treatment technologies. This goal will be attained via a structured training-through-research programme, consisting of original individual research projects (performed both at the - beneficiary organization and through intersectoral secondments) and education on technical and transferable skills (performed both at local level and with network-wide events). The overall research goal of AQUAlity is to develop highly innovative - hybrid green technologies for CECs removal from aqueous systems by unconventional solar advanced oxidation processes (AOP) in combination with high flux ceramic nanofiltration membranes. Hence, ESRs will conduct frontier research in the field of AOP - (organic photocatalysis, sensitized photocatalysts, photo-Fenton), materials development, nanofiltration technology, and will develop innovative hybrid photochemical/membranes systems to be tested on different waters to prove their potential for the - production of high-quality water. Advanced analytical tools for the determination of CECs, their degradation products and water safeness will be developed. Thanks to the presence of industrial participants, AQUAlity aims for the commercial - exploitation of part of the research results. - - 2021-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Italy - - - AQUAlity - - - H2020-MSCA-ITN-2017 - - - 765860 - - - - - KATHOLIEKE UNIVERSITEIT LEUVEN - DOSEVUE - UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM - INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM - - - EUR 3 932 775 - - - ACOUSTIC MARKERS FOR ENHANCED REMOTE SENSING OF RADIATION DOSES - - - EUR 3 932 775 - - - Belgium - Belgium - Italy - Germany - Netherlands - Belgium - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - - Approximately 50% of all cancer patients receive radiation therapy as part of their treatment. The aim is hereby to maximise tumor irradiation and to minimize healthy tissue irradiation. This implies a need for appropriate - dosimetry strategies that can effectively measure the actual radiation dose imparted on the tumor. However, state-of-the-art dosimetry cannot quantify the dose distribution in (and around) the tumor, hereby inhibiting the full potential of - radiotherapy. - - 2021-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-01-2016-2017 - FET-Open research and innovation actions - - - RIA - Research and Innovation action - - - Belgium - - - AMPHORA - - - H2020-FETOPEN-1-2016-2017 - - - 766456 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 173 076 - - - Microdosimetry study of a new radiation therapy method based on proton minibeams - - - EUR 173 076 - - - France - - - Research Organisations - - Radiotherapy (RT) is the medical use of ionising radiation to treat cancer. The main challenge is to deposit a high enough (curative) dose in the tumor while risk organs near the tumour remain at tolerable doses. About 52% of - cancer patients receive RT at least once during treatment. The RT has achieved great success in the cure or palliation of various cancers, but for improving this statistic, new treatment modalities as proton radiotherapy (PT) are rapidly expanding. - PT achieves very high dose conformity around the target, allowing a better protection of the organs at risk (decreasing radiation side effect). However, using PT the dose delivered to a tumour is still conditioned by the dose that can be tolerated by - the surrounding normal tissues. This is particularly critical for certain types of radioresistant tumours, such as hypoxic tumors, for those localized near organs at risk or sensitive structures (e.g. the spinal cord), and paediatrics cancers. For - these types of cancers with poor prognosis it is imperative to find new RT approaches that reduce the normal tissue complication probability (NTCP). A recent novel therapy aim to increase the effective dose therapies by using a distinct dose delivery - method based on proton minibeams (pMBRT). To implement this promising technique at clinical centers, microdosimetric data are required on the radiation quality aspects of proton minibeams to take advantage of their enhanced relative biological - effectiveness versus conventional radiotherapy sources. Currently there are only one array of microdosimeters, as the proposed herein, capable of measuring these parameters in proton therapy. This is the challenge where a candidate approach is - preferred. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - France - - - u-PBeam - - - H2020-MSCA-IF-2016 - - - 745109 - - - - - KUNGLIGA TEKNISKA HOEGSKOLAN - ASTON UNIVERSITY - BIOENERGY 2020+ GMBH - FUNDACION CENER-CIEMAT - ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS - STICHTING WAGENINGEN RESEARCH - STICHTING ENERGIEONDERZOEK CENTRUM NEDERLAND - AGENZIA NAZIONALE PER LE NUOVE TECNOLOGIE, L'ENERGIA E LO SVILUPPO ECONOMICO SOSTENIBILE - KARLSRUHER INSTITUT FUER TECHNOLOGIE - Laboratorio Nacional de Energia e Geologia I.P. - POLITECNICO DI TORINO - STIFTELSEN SINTEF - TECHNISCHE UNIVERSITEIT DELFT - TECHNISCHE UNIVERSITAET GRAZ - Teknologian tutkimuskeskus VTT Oy - - - EUR 9 968 144 - - - Biofuels Research Infrastructure for Sharing Knowledge II - - - EUR 9 977 271,01 - - - Sweden - United Kingdom - Austria - Spain - Greece - Netherlands - Netherlands - Italy - Germany - Portugal - Italy - Norway - Netherlands - Austria - Finland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - The vision of BRISK II is to establish a centre of excellence in the field of 2nd and 3rd generation biofuels via the uniting of leading European research infrastructures. Building upon the success of its FP7 predecessor, - BRISK II Networking Activities will consolidate knowledge in the field, reaching out to a wide set of stakeholders and potential users. Databases generated within the project will serve as a valuable resource for academia and industry. The business - plan will boost momentum beyond H2020 so that the research infrastructures can be utilised between framework programmes or even independently. Joint Research Activities will yield a manifold improvement in the characterisation of feedstocks for - thermochemical and biochemical conversion processes, tying micro-scale and macro-scale phenomena in novel ways. Enhanced measurement techniques will lead to significant gains in process flexibility and reliability. New biorefining approaches are - intended to explore novel process combinations, ones that cannot be tested without a concerted effort between project partners. Assimilated data and knowledge will be input to simulation tools for use in a broad spectrum of analyses. Transnational - Access supports the biofuels research community through the availability of high-quality installations within a well-structured framework. - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.2."> - - - INFRAIA-01-2016-2017 - Integrating Activities for Advanced Communities - - - RIA - Research and Innovation action - - - Sweden - - - BRISK II - - - H2020-INFRAIA-2016-1 - - - 731101 - - - - - UNIVERSITY OF GLASGOW - BAYERISCHE JULIUS-MAXIMILIANS UNIVERSITAT WURZBURG - UNIVERSITAET DUISBURG-ESSEN - UNIVERSIDADE DO ALGARVE - NPL MANAGEMENT LIMITED - UNIVERSITAT AUTONOMA DE BARCELONA - UNIVERSITE DE MONTPELLIER - TECHNISCHE UNIVERSITAET WIEN - CONSIGLIO NAZIONALE DELLE RICERCHE - KEYSIGHT TECHNOLOGIES BELGIUM - - - EUR 3 866 553,36 - - - Doctoral Training Network in Terahertz Technologies for Imaging, Radar and Communication Applications - - - EUR 3 866 553,36 - - - United Kingdom - Germany - Germany - Portugal - United Kingdom - Spain - France - Austria - Italy - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Our future world will be one of ubiquitous sensor systems - a “Real World Web” where billions of devices, machines, or “things” will connect to the internet. In 2008, more machines were connected to the internet than there are - humans on the planet, and by 2020 there are predicted to be 50 billion machines connected to the internet. As a consequence, there will be an ever-increasing hunger for communications bandwidth, both at a local level within an office or apartment, - and at nodes within data centres and server farms. The terahertz (THz) band is yet to be exploited, and occupies frequencies from 0.3 to 3 GHz (1mm to 100um) occupying a middle ground between microwaves and infrared light. THz technologies are also - set to revolutionize a range of imaging, sensing, and quantum optics applications. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - TeraApps - - - H2020-MSCA-ITN-2017 - - - 765426 - - - - - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH - ASG SUPERCONDUCTORS SPA - BABCOCK NOELL GMBH - ELYTT ENERGY SL - OXFORD INSTRUMENTS NANOTECHNOLOGY TOOLS LIMITED - SIGMAPHI - TESLA ENGINEERING LIMITED - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - KARLSRUHER INSTITUT FUER TECHNOLOGIE - PAUL SCHERRER INSTITUT - SCIENCE AND TECHNOLOGY FACILITIES COUNCIL - - - EUR 501 097,50 - - - Future Superconducting Magnet Technology - - - EUR 501 097,50 - - - France - Switzerland - Italy - Germany - Spain - United Kingdom - France - United Kingdom - France - Germany - Switzerland - United Kingdom - - - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - - The CERN’s projects, HL-LHC and FCC, will create a big push in the state of the art of High-Field Superconducting magnets in the ten coming years. The performance of superconducting materials such as Nb3Sn and HTS will be - developed to yield higher performance at lower costs and the construction materials and techniques will be advanced. At the same time, in the context of Energy’s savings, Industry is experiencing a renewed interest in the domain of industrial - superconductivity with fault current limiters, wind generators, electric energy storage, etc. Besides, Medical Research shows a strong interest in High-Field MRI, especially for the brain observation. Considering the social impact of the investment - of the HL-LHC project and FCC study, CERN and CEA have established a Working Group on Future Superconducting Magnet Technology (FuSuMaTech).The Working Group has explored a large spectrum of possible synergies with Industry, and has proposed a set of - relevant R&D&I projects to be conducted between Academia and industry. To keep the leading position of Europe in the domain, the most efficient way is to support joint activities of Industry and academic partners on the common concerns in - view of overcoming the technological barriers. The FuSuMaTech Initiative aims to create the frame of collaborations and to provide common tools to all the EU actors of the domain. The FuSuMatech Initiative is a dedicated and large scale silo breaking - programme which will create a sustainable European Cluster in applied Superconductivity. It will enlarge the innovative potential especially in High Field NMR and MRI, opening future breakthroughs in the brain observation. The FuSuMaTech Phase 1 is - the first step of the FuSuMaTech Initiative. It is based on practical cases studies and will consist in preparing: - - 2019-04-30, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-03-2017 - FET-Open Coordination and Support Actions - - - CSA - Coordination and support action - - - France - - - FuSuMaTech - - - H2020-FETOPEN-3-2017 - - - 766974 - - - - - UNIVERSITY OF LEEDS - - - EUR 195 454,80 - - - Testing communication strategies to save lives in emergency evacuation - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The EU urgently seeks to improve emergency evacuation preparedness. EU public spaces are getting more crowded. Fires and terrorist attacks require emergency evacuation. Faster evacuation from public buildings during - emergencies saves more lives. Observations of actual emergencies show that people tend to be slow to respond to evacuation alarms (taking up to 10 minutes) and take the familiar route out instead of the nearest exit. The EU calls for evidence-based - recommendations for evacuations, which are mostly non-existent. The state of the art uses computer models of evacuation speed, but more realism is needed. We take the novel approach of combining state of the art computer modeling with insights from - risk communication to improve speed and survival in emergency evacuations. This project aims to: - - - 2020-02-29, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - EVACUATION - - - H2020-MSCA-IF-2016 - - - 748647 - - - - - THE UNIVERSITY OF BIRMINGHAM - - - EUR 183 454,80 - - - Design of Hyper Tall Onshore Wind Turbine Towers - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - "HYPER TOWER is a very promising project that will lead to a radical increase in the wind turbine tower height and consequently to an increase in the energy potential harvested by wind structures. The project reaches its aims - of constructing taller, more robust and economical towers by realizing 6 work packages that are formulated and developed in 2 years. In approaching the ""20-20-20"" targets, more and more energy has to come from sustainable energy sources and since - ""The taller the wind tower is, the greener the energy is"", a constant trend of taller wind energy structures is observed. The civil engineers' challenge of constructing taller structures, with heavier machinery hanging at greater heights has led to - the need of evolution of a new tower configuration that can reassure the structure's robustness along with a feasible construction schedule. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - HYPER TOWER - - - H2020-MSCA-IF-2016 - - - 747921 - - - - - Fundació Institut d'Investigació Biomèdica de Bellvitge - - - EUR 158 121,60 - - - Activation of PI3K signalling in the pathogenesis of Vascular Anomalies - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - Vascular anomalies are rare soft tissue tumours and malformations formed by abnormal vascular elements of various types, and mainly affect infants, children and young adults. These lesions are painful, many lead to bleeding, - infections, organ dysfunction, and they can damage and metastasise to other tissues. Current treatment strategies are invasive, not fully efficient, and there is a high risk of recurrence. To date no specific targeted therapies have been developed. - Most of the studies on vascular anomalies are descriptive and focused on their clinical aspects; at the moment, there is a lack of molecular understanding and pre-clinical studies on the field of vascular anomalies. Thus, identifying the causative - molecular alterations of vascular anomalies and understanding their biology will lead to more refined diagnoses and will provide better and more directed therapies. Recent published and unpublished observations from our laboratory show that - activation of phosphoinositide 3-kinase (PI3K) signalling pathway drive to the developments of a fraction of vascular anomalies; however, the underlying molecular and cellular mechanisms remain enigmatic. In this proposal we aim to (i) unveil - alterations in the PI3K signalling pathway components that are involved in the pathogenesis of vascular anomalies, (ii) understand the role of PI3K pathway activation in the development and maintenance of these lesions, and (iii) explore the - potential of repurposing PI3K pathway inhibitors for these conditions. For this, we have set up collaboration with clinicians who will provide a large collection of vascular anomalies from patients. Also, in collaboration with Pharma, we aim to use - PI3K inhibitors for these diseases. Importantly, these collaborations will allow us to translate our findings into the clinic for future clinical trials. This project proposal seeks to broad our understanding of PI3K activation in vascular biology - and to ultimately improve patients’ quality of life. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - PI3K-VAs - - - H2020-MSCA-IF-2016 - - - 749731 - - - - - UNIVERSITY OF BRISTOL - - - EUR 183 454,80 - - - A General Strategy for the Iterative Assembly of Complex 1,3-Polyol Motifs - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - An attractive approach to preparing molecules with common repeat units is iterative synthesis, an approach that is extensively used by Nature in the synthesis of large biomolecules. Nature also uses this tactic for - small-molecule synthesis even though common repeat units are not always immediately apparent, the archetypical example being polyketide synthesis. In contrast, iterative strategies in chemical synthesis are often much less efficient requiring several - functional-group interconversions and purifications between chain-extension steps. We recently reported an “Assembly Line Synthesis” method for the iterative, reagent-controlled homologation (chain extension) of a boronic ester. This process enabled - the conversion of a simple boronic ester into a molecule bearing 10 contiguous methyl substituents in an effectively “one-pot” process. Whilst these methyl-rich carbon chains are rare in natural products, hydroxyl-rich carbon chains (1,3-polyols) are - ubiquitous and often show pronounced and useful biological activity. It would therefore be very useful if this or a related strategy could be applied to the fully stereocontrolled synthesis of 1,3-polyols. Herein, we outline a general strategy for - the synthesis of 1,3-polyols that hinges on the merging of two well-established methodologies: lithiation–borylation and catalytic diboration. We expect to achieve complete control over both relative and absolute stereochemistry in the iterative - synthesis of 1,3-polyboronic esters, enabling stereochemistry to be essentially dialled-in. Subsequent oxidation of the boron esters reveals the desired 1,3-related polyol. The strategy will be applied to the total synthesis of one of the most - complex polyols known, bahamaolide A, a macrocyclic polyol–polyene natural product with potent antifungal properties. This strategy promises to be the most efficient synthetic route to these highly biologically active and hugely important class of - compounds. - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - GRITAP - - - H2020-MSCA-IF-2016 - - - 746045 - - - - - INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM - - - EUR 144 000 - - - Surface Promoted Enhanced Transport of Li-ions - - - EUR 144 000 - - - Belgium - - - Research Organisations - - As a rechargeable energy source lithium ion batteries (LIB) with a solid-state electrolyte is a highly desired option compared to LIB with liquid electrolytes due to several advantages, such as improved safety and extended - lifetime, in addition to enabling devices with both high energy and power densities. However, despite an extensive research effort in this field development of all-solid-state batteries have not yet started to reached its full potential, largely - because of the lack of suitable electrolyte candidate materials that offers both high ionic conductivity and good electrochemical stability. We propose, within SUPER-Lion, the use of a novel nano composite electrolyte (NCE) that would enable - solid-state LIB to reach their full potential, achieving both high ionic conductivities, combined with good mechanical and electrochemical stability. The NCE consists of a nanoporous insulator that provides both mechanical stability and a high - effective internal surface area. The internal surface of the nanoporous matrix is coated with nanometer thin layers of a lithium salt that supply the necessary Li+ ions. The enhanced ion transport at the interface between the surface of the insulator - and the lithium salt is exploited to make a NCE with high ion conductivity. By exploiting the effect of nanoconfinment the ionic conductivity of such interfaces can be enhanced by several orders of magnitude through an effect described as superionic - transitions. The NCE will be manufactured through the combination of atomic layer deposition (ALD) and molecular layer deposition (MLD). Due to the self-limiting nature of the ALD/MLD technique it is perfect for deposition of thin layers where - uniformity, subatomic thickness control and high quality films are of utter most importance. The ALD/MLD technique also enables the NCE to be deposited on 3D structured electrodes with high aspect ratios, thus enabling a further increase in the power - and energy density of all-solid state batteries. - - 2018-11-14, ongoing project - - - 2017-03-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Belgium - - - SUPER-Lion - - - H2020-MSCA-IF-2016 - - - 752716 - - - - - UNIVERSITY OF BRISTOL - - - EUR 195 454,80 - - - Biodegradable Water-Soluble Cylindrical Block Copolymer Micelles and their Applications in Nanomedicine - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Block copolymer (BCP) self-assembly in solution has attracted considerable attention for many decades because it can yield ordered nanoscopic core-shell structures (micelles) with a wide range of morphologies. These aggregates - offer potential applications in many fields, and cylinders are among the most promising for uses in nanomedicine (e.g. as drug delivery vehicles). In this proposal, state-of-the-art strategies to access well-defined micelles with tailored structures - will be applied to the preparation of biodegradable monodisperse cylindrical micelles and block comicelles in water. Once formed, the micelles and their hierarchical assemblies will be characterized in detail and explored in potential nanomedical - applications. To achieve these objectives Dr. Jia Tian, an exceptionally talented young scientist from China who performed his Ph.D. in a top supramolecular chemistry group in China (Zhan-Ting Li, Fudan University), will work in the internationally - leading polymer and materials research group of Prof. Ian Manners (Bristol, UK) where he will learn polymer synthesis and state-of-the-art self-assembly techniques and will obtain a broad background in polymer and BCP synthesis, self-assembly, and - polymer materials science. Armed with the new knowledge and experience gained, following the fellowship Dr. Tian aims to obtain an academic position in China where soft materials such as biodegradable BCPs and their applications in nanomedicine will - play a key role. - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - JTIM - - - H2020-MSCA-IF-2016 - - - 750527 - - - - - FREIE UNIVERSITAET BERLIN - - - EUR 159 460,80 - - - Characterisation method for spin-dependent processes in solar energy technology - - - EUR 159 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - In the search for renewable energy sources, solar energy shows great promise through its conversion to electricity and storable fuels using artificial photosynthesis. A detailed understanding of the energy conversion processes - on the nanoscale is needed for the rational design and improvement of solar technology. This project is aimed at the development of a methodology for in-depth characterisation of spin-dependent processes in solar energy devices. The method will be - based on a novel combination of pulse Electron Spin Resonance (ESR) and Electrically Detected Magnetic Resonance (EDMR) spectroscopy with arbitrarily shaped pulses. ESR by itself has already proven to be instrumental for advancing the understanding - of natural photosynthesis and the increased sensitivity of EDMR allows the extension of this technique to assembled devices. - - 2019-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - SpinSolar - - - H2020-MSCA-IF-2016 - - - 743419 - - - - - UNIVERSITEIT LEIDEN - - - EUR 177 598,80 - - - Investigating the mechanisms that shape galaxies in and around massive clusters - - - EUR 177 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - For decades, astronomers have known that some galaxies are living in dense associations known as “galaxy clusters”, and that many of their properties, e.g. their morphology, colour, and gas content, differ from those of - galaxies living in more isolated parts of the Universe (like our Milky Way). However, understanding the physical origin of these differences has so far proved elusive, constituting a major gap in our understanding of galaxy formation. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - ClusterGal - - - H2020-MSCA-IF-2016 - - - 747645 - - - - - USTAV PRO SOUDOBE DEJINY AV CR V.V.I - - - EUR 142 720,80 - - - Articulating the free market: A cultural history of the economic transformation in Central Europe, 1989-1999 - - - EUR 142 720,80 - - - Czech Republic - - - Research Organisations - - This project excavates how cultural production was influenced by and interacted with the introduction of free market mechanisms in Central Europe after 1989. Concentrating specifically on the 1990s, it argues that this decade - now deserves to be studied historically, rather than being understood as part of a present “post-communist” condition. The collapse of state socialism and (re)instatement of democracy has been theorised from an economic, political, and social - perspective, but its significance for cultural production has been neglected. This project analyses how this economic change was perceived and rooted in society through cultural representations. Specifically, it investigates how the fields of cinema - and television responded to the introduction of a free market economy in Poland, Czech Republic, and Slovakia. Its main object of investigation is the reciprocal relationship between the effects of economic change on cultural production and this - production as an agent in economic change. The proposed research will attend to the cultural dimension of the economic transformation in order to understand the symbolic meanings and narratives that gave the economic and political changes coherence - and social validity at the time. - - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Czech Republic - - - ATFM - - - H2020-MSCA-IF-2016 - - - 749475 - - - - - THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS - - - EUR 183 454,80 - - - Development of highly efficient and stable organic light-emitting diodes based on delayed fluorescent materials for solid-state lighting applications - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - At present, OLED technology is expected to be practically applied to flat panel displays and solid state lighting sources because of its unique characteristics of low-cost processing, flexibility, and low power consumption. - Till date, a large number of fluorescent and phosphorescent materials have been developed to improve the electroluminescence (EL) efficiency of OLEDs. As a result, highly durable and practically applicable OLEDs using these materials have been - realized. However, the internal quantum efficiency of OLEDs based on fluorescent materials is only 25% because of the limit imposed by the electron spin-statistics under electrical excitation. In contrast, OLEDs using phosphorescent materials based - on luminescence from the triplet state can achieve 100% internal quantum efficiency. Recently, an alternative realistic approach, called thermally activated delayed fluorescence (TADF), has been established to obtain ultimate 100% internal EL quantum - efficiency in organic light-emitting diodes (OLEDs). But owing to rather a long transient lifetime of the triplet excited states, high efficiency roll-off and low operational stability at high current density are pertaining concerns in TADF based - OLEDs. To address these challenges, the present state-of-the-art TADF-OLED technology uses a TADF molecule as an assistant dopant and a fluorescent molecule as an end emitter in a host matrix, called TADF assisted fluorescence (TAF-OLED). However, - TAF-OLED approach has several inherent technical challenges associated with device physics, fabrication and cost. Through this research proposal we present a more simplified and realistic approach, called TADF hosted fluorescence (THF), to enhance - the performance and operational stability by using TADF material as host material and fluorescent molecule as end emitter eliminating the need of external host matrix thus mitigate the technical issues associated with TAF-OLEDs. - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - THF-OLED - - - H2020-MSCA-IF-2016 - - - 748430 - - - - - UNIVERSITY OF BRISTOL - - - EUR 183 454,80 - - - Synthesis of sp3-Rich Organofluorine Compounds through Homologation of Boronic Esters - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Organofluorine compounds are highly sought after owing to diverse and numerous applications that take advantage of the unique properties imparted by the presence of one or more C–F bonds. The chemical stability and - conformational landscape of molecules, together with the small size of the fluorine atom, has the made the replacement of a C–H or C–OH bond with a C–F one of the most rewarding modifications during the hit-to-lead stage in medicinal chemistry - programs. Because many applications are dependent on the absolute and relative configuration of the fluorine-containing group, methods that can introduce such groups in a stereoselective manner are particularly attractive. - - - 2019-07-26, ongoing project - - - 2017-07-27 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - FOOTLOOSE - - - H2020-MSCA-IF-2016 - - - 749862 - - - - - UNIVERSITY OF BRISTOL - - - EUR 195 454,80 - - - Novel smart glyco-nanomaterials as targeted therapeutics. - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Cell surface carbohydrates play key roles in cell recognition mechanisms. Protein-carbohydrate interactions typically exhibit high specificity and weak affinities toward their carbohydrate ligand. This low affinity is - compensated in nature by the architecture of the protein, the host presenting the carbohydrate ligands in a multivalent manner or as clusters on the cell or mucosal surface. O-glycosylation is a ubiquitous post-translational modification that is - highly dynamic and responsive to cellular stimuli through the action of the cycling enzymes. Expression of specific O-glycans is linked to changes in gene expression in, for example, inflammatory bowel disease, cystic fibrosis and several types of - cancer. Understanding these glycosylation patterns at molecular and functional levels will allow mechanisms associated with bacterial-host interactions, bowel disease and other cancers to be defined, which will facilitate the development of new - effective therapeutics and diagnostic tools for these conditions. The proposal centers on the chemo-enzymatic synthesis of novel multivalent mucin-type O-glycan probes for the screening of O-glycosylation-linked interactions in health and in disease - and the development of smart glyco-nanoparticles as drug delivery systems. This is a multidisciplinary project involving synthetic organic and inorganic chemistry and glycobiology. - - 2019-10-09, ongoing project - - - 2017-10-10 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - Glyco-Platforms - - - H2020-MSCA-IF-2016 - - - 748103 - - - - - UNIVERSITY OF HULL - NOVA ID FCT - ASSOCIACAO PARA A INOVACAO E DESENVOLVIMENTO DA FCT - UNIVERSIDADE ABERTA - UNIVERSITEIT UTRECHT - UNIVERSITAET GRAZ - UNIVERSITE DE TECHNOLOGIE DE TROYES - UNIVERSITA DEGLI STUDI DI MESSINA - UNIVERSITA DEGLI STUDI GABRIELE D'ANNUNZIO DI CHIETI-PESCARA - - - EUR 3 854 797,56 - - - CiRcular Economy: SusTainability Implications and guidING progress - - - EUR 3 854 797,56 - - - United Kingdom - Portugal - Portugal - Netherlands - Austria - France - Italy - Italy - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - CRESTING will train Early Stage Researchers (ESR) in cutting edge systematic analysis of the process of transformation to a Circular Economy (CE). Establishing a CE (such that the maximum value is extracted from materials and - waste generation minimised) is a major policy area within the European Union and elsewhere. Explicitly seen as increasing economic competitiveness and laying a foundation for environmental employment, CE policies are designed to increase resource - efficiency and decrease carbon dependency. Previous and ongoing research into the CE, however, has been largely concerned with strategies for implementation. The many different fields of activity comprising the CE (e.g., re-use, recovery, recycling, - eco-design amongst others) operate with varying degrees of effectiveness in different places and for different materials. These fields of activity have not been critically analysed as an interrelated social, technical, environmental and, - significantly, spatial phenomenon. This programme will advance the critical analysis of the concept and sustainability implications of the CE by the training of 15 ESR analysing CE-related activity and initiatives in a range of geographic and - economic settings. CRESTING is divided between 5 work packages (WP) analysing: current discourse and policy contexts (WP1); corporate engagement with the CE (WP2); public sector engagement in the CE (WP3); the potential for local economic development - and employment from the CE (WP4); and measuring life cycle impacts and developing sustainability indicators relevant to the CE (WP5). With multidisciplinary and international supervisory teams including non-academic partners within each WP, CRESTING - will 1) analyse the sustainability implications of the CE; 2) analyse the spatial dimension of the CE and 3) translate these analyses into specific actions for managing the transformation to the CE. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - CRESTING - - - H2020-MSCA-ITN-2017 - - - 765198 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 158 121,60 - - - Geometric and analytic aspects of isoparametric hypersurfaces - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - Isoparametric hypersurfaces are intriguing geometric objects whose study has revealed connections with several areas of mathematics and mathematical physics, and which have typically been investigated with differential - geometric, algebraic or topological techniques. - - 2019-04-15, ongoing project - - - 2017-04-16 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - ISOPARAMETRIC - - - H2020-MSCA-IF-2016 - - - 745722 - - - - - TECHNISCHE UNIVERSITEIT DELFT - - - EUR 151 798,90 - - - Asynchronous Time-domain Neural Recording Interfaces - - - EUR 151 798,90 - - - Netherlands - - - Higher or Secondary Education Establishments - - Implantable neural recording devices are being used by neuroscientists and neurosurgeons for monitoring the behaviour of particular parts of the brain. With the advancement of microelectronics manufacturing processes, wireless - multi-channel neural recording systems have become available during the last decade. However, the capabilities of neural recording implants are still limited by their power density in order not to harm the surrounding tissue by heat generation, and - by their total power consumption which limits the operational longevity of the implant. If the operational capabilities and longevity of the neural recording implants are to be improved, new methods of power consumption reduction are required. - - 2019-07-17, ongoing project - - - 2017-09-18 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - Netherlands - - - ATiNaRI - - - H2020-MSCA-IF-2016 - - - 752819 - - - - - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - ELESTOR BV - BAR ILAN UNIVERSITY - MAGYAR TUDOMANYOS AKADEMIA TERMESZETTUDOMANYI KUTATOKOZPONT - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - JENABATTERIES GMBH - AMER-SIL SA - INDUSTRIE DE NORA SPA-IDN - ZURCHER HOCHSCHULE FUR ANGEWANDTE WISSENSCHAFTEN - VYSOKA SKOLA CHEMICKO-TECHNOLOGICKA V PRAZE - UNIVERSITAET STUTTGART - - - EUR 3 796 578,36 - - - European Training Network to improve materials for high-performance, low-cost next- generation redox-flow batteries - - - EUR 3 796 578,36 - - - Germany - Netherlands - Israel - Hungary - France - Germany - Luxembourg - Italy - Switzerland - Czech Republic - Germany - - - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Renewable energy sources like wind turbines require large-scale, stationary energy storage systems to balance out fluctuations in energy generation. FlowCamp will advance the development of one of the most promising storage - systems: redox-flow batteries (RFBs). The recruited fellows will develop materials (membranes, electrodes, electrolytes, catalysts, sealing materials) and macrohomogeneous models for three next generation RFBs (hydrogen-bromine, organic and zinc-air - systems). They will then upscale the new systems to prototype level (TRL4/5), and validate them using the cutting-edge battery testing facilities available for the prestigious German-funded RedoxWind project at Fraunhofer ICT. The new RFB - technologies can be combined in energy storage systems tailored to a wide variety of application scenarios, with lower cost, longer service life and higher efficiency than conventional (e.g. Li-ion) storage devices. - - - 2021-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - FlowCamp - - - H2020-MSCA-ITN-2017 - - - 765289 - - - - - UNIVERSITY OF BRISTOL - - - EUR 195 454,80 - - - The impact of literary translation funding on the transnational mobility of minor European literatures. - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - This project will investigate the rationale, function and impact of funding for the translation, publication and promotion of European literature. State, supranational and third-sector structures for funding translations have - been in place for several decades across Europe, promoting literary and cultural diversity. Applying sociological tools to translation, literary and cultural studies, this research will analyse how recent and current schemes inform practical - decisions on acquisition, publishing and marketing strategies by target publishers across multiple European countries. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - United Kingdom - - - Apricale - - - H2020-MSCA-IF-2016 - - - 749871 - - - - - UNIVERSITY OF LEEDS - - - EUR 195 454,80 - - - Living Well: Provisioning Systems for Sustainable Resource Use and Human Well-Being - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Humanity faces the challenge of how to achieve a high level of well-being for all people without destabilizing the planetary processes that facilitated the rise of civilization. This project revolves around the intermediating - role of physical and social provisioning systems that link resource use and social outcomes. Provisioning systems mediate the relationship between biophysical inputs and social outcomes via the material practices and cultural meanings associated with - the consumption of specific commodities (i.e. energy, housing, transport, etc.). A better understanding of provisioning systems can provide insight on how to achieve high levels of well-being at low levels of resource consumption that are within - planetary boundaries. - - 2019-10-01, ongoing project - - - 2017-10-02 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - LIVEWELL - - - H2020-MSCA-IF-2016 - - - 752358 - - - - - UNIVERSITY OF DURHAM - - - EUR 183 454,80 - - - fault STRength breAkdown and Implications for earthquake Nucleation - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Our ability to limit the societal and economic impact of the earthquakes is strongly tied to our understanding of the physics lying behind the earthquake phenomenology. Most earthquakes are generated along pre-existing faults - that suddenly fail after prolonged periods of tectonic stressing. Indeed, an earthquake is generated by the imbalance between the elastic energy provided by the rocks surrounding the fault and the strength drop of the fault itself, which is degraded - by progressive slip. A large number of experimental and geophysical data well characterize the first-order resistance of the rocks either before (“static” strength) or after the initiation of seismic slip (“dynamic” strength). However, there is a - fundamental lack of understanding about how exactly the fault strength decrease slip (STRAIN weakening) and about the real elasticity of the rock masses around the fault, i.e. the “spring” that triggers the earthquakes. We propose the first - systematic study of the changes in rock strength with progressive strain using two world-class deformation apparatuses hosted at Durham University, integrating a wide range of microstructural observations and lab seismology techniques to have - insights into the microphysics of deformation. We also propose to acquire an unprecedented dataset on the elasticity of fault rocks at in situ conditions, which will be combined with shear experiments to produce empirically calibrated models of fault - zone that may shed new light on the process of earthquake nucleation and of potential seismic precursors. - - 2019-09-10, ongoing project - - - 2017-09-11 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - STRAIN - - - H2020-MSCA-IF-2016 - - - 748400 - - - - - UNIVERSITY OF BRISTOL - - - EUR 183 454,80 - - - Stereoregular Inorganic Polymer Analogues of Polyolefins - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Inorganic polymers are of great interest as a result of their interesting properties, which offer exciting opportunities for their use as functional materials. Currently inorganic polymers generated through dehydrocoupling of - group 13/15 amine- or phosphine-borane adducts are atactic and lack crystallinity, precluding their use in a variety of applications. The proposed research targets stereoregular polyaminoboranes and polyphosphinoboranes, inorganic analogues of - stereoregular polyolefins, and potentially block copolymers, through catalytic dehydropolymerization using chiral earth abundant transition metal catalysts. The stereoregular polymers and block copolymers will be characterized in detail, and - potential applications explored. To achieve these objectives a highly talented young scientist, Dr. Vincent Annibale, wishes to work in the highly multidisciplinary and internationally leading research group of Prof. Ian Manners at the University of - Bristol for 2 years. Dr. Annibale has a wealth of expertise in synthetic transition metal chemistry from his previous postdoctoral and Ph.D. work. With a Marie Sklodowska Fellowship Dr. Annibale would gain exceptionally valuable experience and would - become proficient in the field of polymer and materials science, which would be extremely important for his future career, preferably in academia, or in industry. - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - VAIM - - - H2020-MSCA-IF-2016 - - - 748371 - - - - - INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER - FUNDACION AZTI - AZTI FUNDAZIOA - BLUE LOBSTER IT LIMITED - THE SECRETARY OF STATE FOR ENVIRONMENT, FOOD AND RURAL AFFAIRS - FONDAZIONE CENTRO EURO-MEDITERRANEO SUI CAMBIAMENTI CLIMATICI - CONSIGLIO NAZIONALE DELLE RICERCHE - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - STICHTING DELTARES - ETT SPA - EUROGOOS - FLUIDION - ILMATIETEEN LAITOS - HELLENIC CENTRE FOR MARINE RESEARCH - HELMHOLTZ-ZENTRUM GEESTHACHT ZENTRUM FUR MATERIAL- UND KUSTENFORSCHUNG GMBH - INSTITUTO HIDROGRAFICO - HAVFORSKNINGSINSTITUTTET - INSTITUTE OF OCEANOLOGY - BULGARIAN ACADEMY OF SCIENCES - INTERNATIONAL RESEARCH INSTITUTE OFSTAVANGER AS - MARIENE INFORMATIE SERVICE MARIS BV - MARINE INSTITUTE - NORSK INSTITUTT FOR VANNFORSKNING - ISTITUTO NAZIONALE DI OCEANOGRAFIA E DI GEOFISICA SPERIMENTALE - MINISTERIE VAN INFRASTRUCTUUR EN MILIEU - SLR ENVIRONMENTAL CONSULTING(IRELAND)LIMITED - SMARTBAY IRELAND - SVERIGES METEOROLOGISKA OCH HYDROLOGISKA INSTITUT - SOCIB - CONSORCIO PARA EL DISENO, CONSTRUCCION, EQUIPAMIENTO Y EXPLOTACION DEL SISTEMA DE OBSERVACION COSTERO DE LAS ILLES BALEARS - SUOMEN YMPARISTOKESKUS - UNIVERSITA TA MALTA - UNIVERSITAT POLITECNICA DE CATALUNYA - VLAAMS INSTITUUT VOOR DE ZEE VZW - EURO-ARGO ERIC - DURAND DOMINIQUE, DENIS, FABRICE - - - EUR 9 998 876,47 - - - Joint European Research Infrastructure network for Coastal Observatory – Novel European eXpertise for coastal observaTories - - - EUR 9 998 876,47 - - - France - Spain - United Kingdom - United Kingdom - Italy - Italy - France - Spain - Netherlands - Italy - Belgium - France - Finland - Greece - Germany - Portugal - Norway - Bulgaria - Norway - Netherlands - Ireland - Norway - Italy - Netherlands - Ireland - Ireland - Sweden - Spain - Finland - Malta - Spain - Belgium - France - Norway - - - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The coastal area is the most productive and dynamic environment of the world ocean with significant resources and services for mankind. - - 2019-08-31, ongoing project | - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.2."> - - - INFRAIA-1-2014-2015 - Integrating and opening existing national and regional research infrastructures of European interest - - - RIA - Research and Innovation action - - - France - - - JERICO-NEXT - - - H2020-INFRAIA-2014-2015 - - - 654410 - - - - - UNIVERSITY OF BRISTOL - - - EUR 183 454,80 - - - A combination of approaches from the molecular to the integrative plant level to understand the bases of stomatal responses to CO2 and their variability - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Understanding plant responses to rising atmospheric CO2 is of major interest given the necessity to select and develop new crop cultivars that will perform better in a changing global climate. By regulating the exchange of - water and CO2 between the interior of the leaf and the atmosphere, stomata -the pores at the leaf surface- play a major role in CO2-mediated processes. Stomatal aperture is constantly adjusted, in response to internal cues and external environmental - signals, through turgor changes of the two guard cells that surround the pore. Plants respond to elevated CO2 levels by reducing stomatal aperture, and recent advances have shed light on the intracellular machinery responsible for this response. - However, little is understood about the variability in stomatal responses to CO2, both among and within species. This project will decipher the main factors responsible for variations in stomatal responses to CO2. It will specifically address the - roles of ABA-signalling, photosynthesis and stomatal morphology in the response of stomatal conductance (gs) to CO2 and how this impacts on plant performance. These will be investigated from the cellular to the level of the whole plant by using the - model plant Arabidopsis thaliana and major European crops. Genetic diversity will be used in different forms (mutants, association studies, inter-specific comparison) to identify the causal factors of variation. The knowledge gained into gs responses - will be integrated into predictive models for water-use efficiency to scale-up to whole plant performance. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - STOCOVAR - - - H2020-MSCA-IF-2016 - - - 740222 - - - - - JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN - - - EUR 239 860,80 - - - Linguistic Dimensions of Sexual Normativity - - - EUR 239 860,80 - - - Germany - - - Higher or Secondary Education Establishments - - LIDISNO is the first large-scale research project that analyses the role of language in the discursive formation of sexual normativity. Based on poststructuralist and Queer Linguistic theorisations of language and sexuality as - discursively shaped, the project highlights the historical relativity and variability of sexual normativity by adducing empirical linguistic evidence from various time periods. In contrast to earlier work, which has largely postulated - sexuality-related discursive shifts without verifying them in larger amounts of linguistic data, LIDISNO uses corpus linguistically informed critical discourse analysis to study the linguistic corollaries of three sexuality-related normative shifts: - 1. language use about a person before and after their public coming out, with US Latino pop singer Ricky Martin as a case study, 2. language use to express same-sex experiences pre- vs. post-Stonewall, and 3. sexuality-related language use before and - after 1890, i.e. the time of the oft-cited desire-to-identity shift in the conceptualisation of sexuality. Each of these shifts is studied through comparisons of pairs of text corpora pre- and post-dating the respective shift, while drawing on - quantitative and qualitative corpus linguistic methods (frequency of sexuality-related features, frequency lists, keyword lists, semantic keyness, concordances, collocations, colligations) with the help of the tools AntConc and Wmatrix. These - linguistic analyses are complemented by a comparison of findings across corpus pairs and comparisons with various types of supplementary data (interviews, personal narratives, major English reference corpora). LIDISNO will improve our understanding - how linguistic practices shape sexual normativity. Its findings will be used to advance the theorisation of normativity as an analytical tool in critical discourse studies and to devise language policies that foster greater tolerance and inclusion of - non-heterosexual individuals. - - 2020-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Germany - - - LIDISNO - - - H2020-MSCA-IF-2016 - - - 740257 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 257 191,20 - - - Towards a unified mechanistic model of oceanic island biogeography - - - EUR 257 191,20 - - - Spain - - - Research Organisations - - Understanding how ecological and evolutionary processes shape patterns of biodiversity remains a central challenge for ecological and biogeographic theory. Oceanic islands, because of their spatiotemporal properties, provide - the most promising arena to address this challenge. UNISLAND will advance general theory by applying novel ecological, evolutionary and genomics approaches to explicitly test mechanistic predictions derived from the recently developed General Dynamic - Model (GDM). The GDM, while an island focused model, is of broad ecological relevance, because it encompasses generally held ecological relationships, such as the species area relationship (SAR) and the species abundance distribution (SAD). Two key - mechanistic predictions derived from the GDM have so far been untested, and are the focus of UNISLAND. The first is that the older an island is, the more old are the single island endemic species (SIEs) that evolved on that island. The second is that - single island endemic species (SIEs) have higher extinction probabilities that other species. UNISLAND is embedded in a multidisciplinary framework involving: comparative phylogenetics; community-level modeling; ‘museum’ genomics; and - spatially-explicit coalescent-based analysis. Data generated by UNISLAND will evaluate the range shift and extinction risk (species-level and ecosystem-level), thus addressing international and European-level research priorities. Through the - collaborative phase between the ER and OPS, UNISLAND will provide the ER with state of the art skills in historical DNA genomics and ecological modelling that will be transferred to the CSIC during the return phase. The complementary research - profiles of the OPS, RPS and ER, their mutual interests in the spatial structuring of biodiversity, and the application of modern fit for purpose methodology, underpin the strength of UNISLAND. - - 2020-09-15, ongoing project - - - 2017-09-16 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Spain - - - UNISLAND - - - H2020-MSCA-IF-2016 - - - 747238 - - - - - ASTON UNIVERSITY - - - EUR 195 454,80 - - - Smart Modulation Methods for Energy Efficient Operation and Health Monitoring of Future Motor Drives - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The goal of this Fellowship, entitled “Smart Modulation Methods for Energy Efficient Operation and Health Monitoring of Future Motor Drives” (SmaMoMeDs) is to train an outstanding researcher (Dr Lassi Aarniovuori) with a - strong academic background through a research project focused on the innovative modulation algorithms for a new technology wide-bandgap gallium nitride (GaN) and silicon carbide (SiC) based inverter bridges (power switches) that will be used in - future motor drives. These new switches allow the use of ultra-high switching frequencies in motor drives, creating opportunities to improve the performance, reliability and energy-efficiency of the motor drives systems. The proposed smart modulation - methods are aimed 1) to identify the motor parameters for the control system, 2) to optimize the modulation method according to the operating conditions, 3) to detect any changes in the mechanical or electrical behavior of the motor parameters for - health monitoring. The applicant Dr. Aarniovuori will be trained in the field of electrical power engineering, power electronics, motors, and drives. These are the key components in any modern industrial applications and they are a part of people’s - everyday live in all welfare societies. The Fellow will get a unique training experience at the host – Aston University its industrial partner Jaguar Landrover (JLR)., its academic partners Newcastle University (UK) and Politecnic Torino (Italy). - - 2019-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SmaMoMeMoDs - - - H2020-MSCA-IF-2016 - - - 746900 - - - - - UNIVERSITY OF BRISTOL - - - EUR 183 454,80 - - - Shark extinctions: past and present - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Species are going extinct at an accelerated rate. Yet, some species are more resilient than others. Understanding what determines species susceptibility to extinction is crucial to address species loss; however, current - knowledge provides mixed clues. SHARKS-XT aims to study fossil and modern sharks to determine what factors can help predicting their extinctions; and to assess if modern sharks are responding differently to current extinction threats, or if the - predictors of the past can aid conservation efforts. To reach our research objectives we propose three work packages (WPs) in which we will: (WP1) integrate what is currently known in palaeontology and neontology to create a comprehensive - trait-dataset of all fossil and living sharks; and employ a novel combination of quantitative methods to establish the relative role and interactions between (WP2) intrinsic (traits) and (WP3) extrinsic (environment) factors in determining extinction - susceptibility. We will then compare our results to assess if the predictors (or interactions between predictors) of extinction are consistent across different timescales. The strength of this proposal lies in the use of sharks as a model because - they: (1) have an abundant fossil record that goes deep in geological time; (2) have shown resilience to major environmental changes in the past; (3) have lower extinction rates, (4) are being affected the most by the current biodiversity crisis; and - (5) play key roles in stabilising marine systems. This research has the potential of assessing how far the rich resources of the fossil record may be used to address modern risks, and could have important societal impacts: by identifying predictors - of shark extinction, the role of the climate in establishing such predictors, and the extent to which the predictors of the past can be used to address today’s extinction crisis; it would be possible to re-focus conservation efforts. - - 2020-05-31, Grant Agreement signed - - - 2018-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SHARKS-XT - - - H2020-MSCA-IF-2016 - - - 745844 - - - - - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - - - EUR 2 492 036 - - - Skill Acquisition in Humans and Robots - - - EUR 2 492 036 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Society is rapidly opening its doors to robots in our daily life with autonomous vehicles, rehabilitation devices and autonomous appliances. These robots will face unexpected changes in their environment, to which they will - have to react immediately and appropriately. Even though robots exceed largely humans’ precision and speed of computation, they are far from matching humans’ capacity to adapt rapidly to unexpected changes. In the past decades, robotics has made - leaps forward in the design of increasingly complex robotic platforms to meet these challenges. In this endeavour, it has benefited from advances in optimization for solving high-dimensional constrained problems and in machine learning (ML) to - analyse vast amounts of data. These methods are powerful for planning in slow-paced tasks and when the environment is known. This project addresses a growing need for methods that show fast and on-line reactivity. - - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Switzerland - - - SAHR - - - ERC-2016-ADG - - - 741945 - - - - - JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN - - - EUR 159 460,80 - - - Artificial Life TodayAnthropological and Sociological Analysis of Life Engineering - - - EUR 159 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - We are witnessing profound changes in our societies via biosciences and bio-technologization. Biotechnologies, synthetic biology, and new genetics in general represent key areas of life sciences, characterised by rapid - technological and scientific development. The biotechnologies as key areas of contemporary cultural and social transformations are influenced by specific technological rationality and power that is inscribed in the very foundations of modern society. - The power is biopower/biopolitics, which names, creates, and controls life. The project addresses contemporary challenges in the field of biopolitical life engineering, specifically in case of PGD (preimplantantion genetic diagnosis) technology. - There is a lack of reflection on the broader social and cultural context and on the ramifications of synthetic life engineering, PGD in the Czech Republic from the anthropological and sociological points of view. These issues remain unanalysed, - contributing to a lack of understanding of the specific concerns of synthetic life and life sciences in the Eastern European and post-socialist context. This proposed project will analyse social context of technology PGD in the Czech Republic in - comparison with Germany. This project is guided by the main questions: How is the field of life engineering, particularly PGD technology, culturally and socially structured in the Czech Republic in comparison with Germany? What kinds and forms of - agency are involved there? Are there any specific concerns in public debates relating to life engineering in comparisons of Eastern and Western Europe? The main aim of this research, which will be conducted on case studies of two European countries, - is to analyse and interpret through sociological and anthropological perspective the ways in which current forms of biopower and ideas of artificial life have been influencing the social field of life engineering, especially PGD technology. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - ARTENGINE - - - H2020-MSCA-IF-2016 - - - 750088 - - - - - UNIVERSITY OF BRISTOL - - - EUR 183 454,80 - - - Boron chemistry in a new light: exploring the radical reactivity of boronate complexes through photochemical strategies - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - In the last decade photoredox reactions have emerged as tremendously versatile processes for organic synthesis, enabling reactive radical species to be generated at specific positions in an organic molecule under very mild - conditions (visible-light irradiation). Over the same decade the host group have developed a suite of transformations exploiting the fundamental chemistry of boron, many of which involve 1,2-metallate rearrangement of boronate complexes. We now seek - to merge these two major pillars of synthetic methodology, which are currently unconnected, to create a new field which we believe has significant potential for organic synthesis. - - - 2019-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - PHOTO-BORAD - - - H2020-MSCA-IF-2016 - - - 744242 - - - - - UNIVERSITA' DEGLI STUDI DI SIENA - VIRTUAL INSTITUTE FOR ARTIFICIAL ELECTROMAGNETIC MATERIALS AND METAMATERIALS - METAMORPHOSE VI AISBL - NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - Teknologian tutkimuskeskus VTT Oy - UNIVERSITA POLITECNICA DELLE MARCHE - KING'S COLLEGE LONDON - FUNDACIO INSTITUT CATALA DE NANOCIENCIA I NANOTECNOLOGIA - I.D.S. - INGEGNERIA DEI SISTEMI - S.P.A. - ECOLE SUPERIEURE DE PHYSIQUE ET DECHIMIE INDUSTRIELLES DE LA VILLE DEPARIS - THALES SA - POLITECNICO DI TORINO - - - EUR 670 000 - - - NANOARCHITECTRONICS - - - EUR 670 000 - - - Italy - Belgium - Netherlands - Germany - Finland - Italy - United Kingdom - Spain - Italy - France - France - Italy - - - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - This FET-open Coordination and Support Action is called “Nanoarchitectronics” (NTX) to denote a new interdisciplinary research area at the crossroad of Electromagnetics and Nanoelectronics. NTX It is a new technology aimed at - conceiving, designing and developing reconfigurable, adaptive and cognitive structures, sensorial surfaces and functional “skins” with unique physical properties, and engineering applications in the whole electromagnetic spectrum; through assembling - building blocks at nanoscale in hierarchical architectures. The conception of this new area responds to the need of unifying concepts, methodologies and technologies in Communications, Environment Sensing Systems, Safety and Security, Bio-Sensing - Systems and Imaging Nanosystems, within a wide frequency range. This FET project proposal gathers thirteen universities, research centers and high-tech industries, belonging to eight European countries. - - - 2018-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-02-2016 - FET-Open Coordination and Support Actions - - - CSA - Coordination and support action - - - Italy - - - NANOARCHITECTRONICS - - - H2020-FETOPEN-2-2016 - - - 737135 - - - - - UNIVERSITY OF BRISTOL - - - EUR 251 857,80 - - - Photo- And Radical induced Reactivity of Atmospheric Oxidants - - - EUR 251 857,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The research program will seek to explore the mechanisms and formation/reaction rates of various oxidizing agents pertinent to tropospheric chemistry, using cutting-edge experimental apparatuses and theoretical methods. - - - 2020-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - PhARRAO - - - H2020-MSCA-IF-2016 - - - 746593 - - - - - INSTITUTE OF EXPERIMENTAL MEDICINE - HUNGARIAN ACADEMY OF SCIENCES - INSTITUTE OF EXPERIMENTAL MEDICINE - HUNGARIAN ACADEMY OF SCIENCES - - - EUR 1 597 575 - - - Specificity of cortico-thalamic interactions and its role in frontal cortical functions - - - EUR 1 597 575 - - - Hungary - Hungary - - - Research Organisations - Research Organisations - - Frontal cortical areas are responsible for a wide range of executive and cognitive functions. Frontal cortices communicate with the thalamus via bidirectional pathways and these connections are indispensable for frontal - cortical operations. Still, we have very little information about the specificity of connections, synaptic interactions and plasticity between frontal cortex and thalamus and the roles of these interactions in frontal cortical functions. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Hungary - - - FRONTHAL - - - ERC-2016-ADG - - - 742595 - - - - - IFOM FONDAZIONE ISTITUTO FIRC DI ONCOLOGIA MOLECOLARE - IFOM FONDAZIONE ISTITUTO FIRC DI ONCOLOGIA MOLECOLARE - - - EUR 2 451 250 - - - Inherited disfunctions of brain microcirculation - - - EUR 2 451 250 - - - Italy - Italy - - - Research Organisations - Research Organisations - - Cerebral cavernous malformations (CCM) is a disease characterized by focal capillary-venous cavernomas located in the central nervous system. These malformations are fragile and bleed leading to seizures, paralysis and - cerebral hemorrhages. The familial form of CCM is due to loss of function mutations of anyone of three genes called Ccm1, Ccm 2 and Ccm 3. Open skull surgery is the only possible therapy since effective medical treatments are still missing. In mouse - models of CCM and human patients’ specimens, endothelial cells (ECs) lining the cavernomas co-express endothelial, mesenchymal and stem cell markers. These features combined to high cell proliferation are reminiscent of tumor initiating cells. In - preliminary work, we isolated a rare population of highly proliferative ECs (V-EPC) intermingled with the normal vascular endothelium in vivo and co-expressing endothelial and stem cell markers. Our working hypothesis is that CCM originates from the - clonal expansion of these V-EPCs that are more sensitive than mature endothelium to inactivation of Ccm genes. This possibility is supported by the observation that V-EPCs present a comparable gene expression profile and selective markers than the - ECs lining CCM cavernomas. The project is divided in three related objectives: 1) To define the nature and functions of V-EPCs in normal vessels; 2) to test the capacity of V-EPCs to trigger the formation of CCM by undergoing clonal expansion in - vivo; 3) to test whether targeting V-EPCs or inducing V-EPC maturation by pharmacological tools reduce or prevent the formation of CCM. If successful this work will introduce novel concepts in vascular biology such as: 1) the presence of resident - V-EPCs that are differentially sensitive than mature endothelium to the same genetic mutation and angiogenic stimuli; 2) the identification of specific signaling pathways in V-EPC that explain their high proliferative potential; 3) the identification - of V-EPC as therapeutic targets for CCM. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Italy - - - V-EPC - - - ERC-2016-ADG - - - 742922 - - - - - TECHNISCHE UNIVERSITEIT EINDHOVEN - TECHNISCHE UNIVERSITEIT EINDHOVEN - - - EUR 150 000 - - - Piloting cascaded continuous flow synthesis for the pharmaceutical industry - - - EUR 150 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - PICASCO aims to deliver the commercial proof of concept of a novel endto- end flow manufacturing and a novel corresponding compact flow mini plant. This is performed through the first continuous 4-step solvent-free flow - manufacturing of a pharmaceutically relevant API compound at an industrial scale. Currently applied batch manufacturing techniques leave much room for improved quality, efficiency, cost-effectiveness and environmental friendliness. Flow multi-step - manufacturing can address all these issues simultaneously, but to date has not been brought to an industrially useful scale. PICASCO sets out to scale this final barrier. - - 2019-02-28, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Netherlands - - - PICASCO - - - ERC-2017-PoC - - - 780765 - - - - - UNIVERSITY OF BRISTOL - UNIVERSITY OF BRISTOL - - - EUR 2 294 320 - - - Mechanisms of electroreception in bees and other terrestrial animals - - - EUR 2 294 320 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Many animal species can detect the electric fields in their environment. Electroreception has mainly been studied in aquatic vertebrates; fish like sharks and rays, gymnotid and mormirid electric fish, the lamprey, the - platypus, the coelacanth, and one mammalian species, a dolphin. We have discovered that bumblebees can detect and learn about the weak electric fields that arise when they approach a flower. This is the first example of electroreception in a - non-conductive medium, aerial electroreception (AE). Recently, we showed that AE can be achieved through the electro-mechanical coupling of mechanosensory hairs to the weak electric field surrounding the animal. This is much like the hair-raising - sensation humans used to experience by browsing an arm near to a cathodic television set. Yet, humans cannot sense the weak electric fields surrounding a flower, so this potentially informative physical quantity had escaped scientific attention. To - date, little is known about AE, its sensory ecology and evolution. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - ElectroBee - - - ERC-2016-ADG - - - 743093 - - - - - UNIVERSITEIT VAN AMSTERDAM - UNIVERSITEIT VAN AMSTERDAM - - - EUR 1 500 000 - - - Mapping the retrotransposon-mediated layer of neuronal gene regulation in the human genome - - - EUR 1 500 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Throughout evolution, the human genome has been attacked by retrotransposons, parasitic DNA elements that spread through our genome by a copy-paste activity. I previously showed that SVA elements, the youngest class of - retrotransposons in our genome, harbour a strong gene-regulatory potential which is normally repressed by KRAB zinc finger protein ZNF91 (Jacobs et al., 2014, Nature). However, for reasons unknown, repression of retrotransposons is much less - efficient in the human brain, resulting in activation of the enhancer potential of SVA elements spread throughout the human genome. The importance of these SVA insertions for the evolution of human neuronal gene-regulatory networks, and how many - genes have come to depend on SVA's regulatory influence, remains elusive. In this research program, I will use ‘cortical organoids’; three-dimensional brain tissues derived from human and primate stem cells, to investigate how recent SVA insertions - have impacted human neuronal gene expression. Furthermore, I will investigate how changes of the epigenetic landscape in neurons affect the activity of retrotransposons in our genome and the influence they have on nearby neuronal genes. Finally, I - will explore the possibility that loss of epigenetic silencing of retrotransposons is responsible for dysregulation of genes associated with neurological diseases. Preliminary findings suggest a potential role for retrotransposons in susceptibility - loci for Alzheimer's and Parkinson's disease. Finding further support for this in the current research program, will form the basis of a novel concept which explains how changes in the epigenetic landscape can uncover a dormant genetic predisposition - to disease. - - 2022-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - PRIMATE-TE-IMPACT - - - ERC-2016-STG - - - 716035 - - - - - UNIVERSIDAD DE OVIEDO - UNIVERSIDAD DE OVIEDO - - - EUR 2 456 250 - - - Deconstructing Ageing: from molecular mechanisms to intervention strategies - - - EUR 2 456 250 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Over many years, our research group has explored the complex relationship between cancer and ageing. As part of this work, we have generated mouse models of protease deficiency which are protected from cancer but exhibit - accelerated ageing. Further studies with these mice have allowed us to unveil novel mechanisms of both normal and pathological ageing, to discover two new human progeroid syndromes, and to develop therapies for the Hutchinson-Gilford progeria - syndrome, now in clinical trials. We have also integrated data from many laboratories to first define The hallmarks of ageing and the current possibilities for Metabolic control of longevity. Now, we propose to leverage our extensive experience in - this field to further explore the relative relevance of cell-intrinsic and -extrinsic mechanisms of ageing. Our central hypothesis is that ageing derives from the combination of both systemic and cell-autonomous deficiencies which lead to the - characteristic loss of fitness associated with this process. Accordingly, it is necessary to integrate multiple approaches to understand the mechanisms underlying ageing. This integrative and multidisciplinary project is organized around three major - aims: 1) to characterize critical cell-intrinsic alterations which drive ageing; 2) to investigate ageing as a systemic process; and 3) to design intervention strategies aimed at expanding longevity. To fully address these objectives, we will use - both hypothesis-driven and unbiased approaches, including next-generation sequencing, genome editing, and cell reprogramming. We will also perform in vivo experiments with mouse models of premature ageing, genomic and metagenomic studies with short- - and long-lived organisms, and functional analyses with human samples from both progeria patients and centenarians. The information derived from this project will provide new insights into the molecular mechanisms of ageing and may lead to discover - new opportunities to extend human healthspan. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Spain - - - DeAge - - - ERC-2016-ADG - - - 742067 - - - - - BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION - - - EUR 170 121,60 - - - Advanced Ecosystem for Broad Heterogeneous Memory Usage - - - EUR 170 121,60 - - - Spain - - - Research Organisations - - Supercomputers are a key tool for professionals from many disciplines to address society challenges, enabling them to perform, e.g., climate change simulations or genome analysis. EC’s HPC Strategy, implemented in H2020, - devises the need to bring Europe's high-performance computing technology to the exascale era, being energy efficiency one of the major challenges. Since providing the required amount of memory for upcoming exascale applications is non-viable by means - of top-performance technology only, due to energy consumption and dissipation constraints, vendors are incorporating a variety of additional memory subsystems built upon different technologies, which provide diverse features and limitations (e.g., - Intel’s Knights Landing processor). Deciding what data to host in each memory subsystem is far from trivial and poses notable performance implications. Recent research has focused on their use for specific purposes such as resilience or to host - selected data objects based on some basic criteria. The aim of this project is to move a big step forward and develop technology to build an innovative generic software ecosystem to facilitate the efficient use of heterogeneous memory systems, what - will be crucial to leverage the full potential of exascale platforms. BSC is an excellent institution to develop this research because of its top-level facilities and researchers, its multiple collaborations with industry, and the exceptional - training, dissemination, and communication opportunities it offers. While Prof. Ayguadé will supervise this fellowship bringing the experience of a brilliant consolidated career and leading roles in European projects, technology transfer to Intel - will boost the impact of the project. This undoubtedly represents an outstanding opportunity for the candidate to complement his GPU Computing experience, consolidating his research career in system software for many-core architectures while - reintegrating in a long-term position in Europe. - - 2020-02-29, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Spain - - - ECO-H-MEM - - - H2020-MSCA-IF-2016 - - - 749516 - - - - - JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN - JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN - - - EUR 2 497 140 - - - Acetogenic bacteria: from basic physiology via gene regulation to application in industrial biotechnology - - - EUR 2 497 140 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Demand for biofuels and other biologically derived commodities is growing worldwide as efforts increase to reduce reliance on fossil fuels and to limit climate change. Most commercial approaches rely on fermentations of - organic matter with its inherent problems in producing CO2 and being in conflict with the food supply of humans. These problems are avoided if CO2 can be used as feedstock. Autotrophic organisms can fix CO2 by producing chemicals that are used as - building blocks for the synthesis of cellular components (Biomass). Acetate-forming bacteria (acetogens) do neither require light nor oxygen for this and they can be used in bioreactors to reduce CO2 with hydrogen gas, carbon monoxide or an organic - substrate. Gas fermentation using these bacteria has already been realized on an industrial level in two pre-commercial 100,000 gal/yr demonstration facilities to produce fuel ethanol from abundant waste gas resources (by LanzaTech). Acetogens can - metabolise a wide variety of substrates that could be used for the production of biocommodities. However, their broad use to produce biofuels and platform chemicals from substrates other than gases or together with gases is hampered by our very - limited knowledge about their metabolism and ability to use different substrates simultaneously. Nearly nothing is known about regulatory processes involved in substrate utilization or product formation but this is an absolute requirement for - metabolic engineering approaches. The aim of this project is to provide this basic knowledge about metabolic routes in the acetogenic model strain Acetobacterium woodii and their regulation. We will unravel the function of “organelles” found in this - bacterium and explore their potential as bio-nanoreactors for the production of biocommodities and pave the road for the industrial use of A. woodii in energy (hydrogen) storage. Thus, this project creates cutting-edge opportunities for the - development of biosustainable technologies in Europe. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - ACETOGENS - - - ERC-2016-ADG - - - 741791 - - - - - UNIVERSITAT AUTONOMA DE BARCELONA - UNIVERSITAT AUTONOMA DE BARCELONA - - - EUR 1 943 924 - - - Behavioral-evolutionary analysis of climate policy: Bounded rationality, markets and social interactions - - - EUR 1 943 924 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Distinct climate policies are studied with incomparable approaches involving unique criteria and impacts. I propose to unite core features of such approaches within a behavioral-evolutionary framework, offering three - advantages: evaluate the effectiveness of very different climate policy instruments in a consistent and comparative way; examine policy mixes by considering interaction between instruments from a behavioral as well as systemic perspective; and - simultaneously assessing policy impacts mediated by markets and social interactions. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Spain - - - EVOCLIM - - - ERC-2016-ADG - - - 741087 - - - - - UNIVERSITY OF BRISTOL - UNIVERSITY OF BRISTOL - - - EUR 2 495 578 - - - Generalization in Mind and Machine - - - EUR 2 495 578 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Is the human mind a symbolic computational device? This issue was at the core Chomsky’s critique of Skinner in the 1960s, and motivated the debates regarding Parallel Distributed Processing models developed in the 1980s. The - recent successes of “deep” networks make this issue topical for psychology and neuroscience, and it raises the question of whether symbols are needed for artificial intelligence more generally. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - M and M - - - ERC-2016-ADG - - - 741134 - - - - - POLITECNICO DI MILANO - POLITECNICO DI MILANO - - - EUR 2 351 544 - - - An Integrated Heart Model for the simulation of the cardiac function - - - EUR 2 351 544 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The goal of this project is to construct, mathematically analyze, numerically approximate, computationally solve, and validate on clinically relevant cases a mathematically-based integrated heart model (IHM) for the human - cardiac function. The IHM comprises several core cardiac models – electrophysiology, solid and fluid mechanics, microscopic cellular force generation, and valve dynamics – which are then coupled and finally embedded into the systemic and pulmonary - blood circulations. It is a multiscale system of Partial Differential Equations (PDEs) and Ordinary Differential Equations (ODEs) featuring multiphysics interactions among the core models. - - 2022-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Italy - - - iHEART - - - ERC-2016-ADG - - - 740132 - - - - - UNIVERSITEIT LEIDEN - UNIVERSITEIT LEIDEN - - - EUR 1 999 761 - - - Food citizens? Collective food procurement in European cities: solidarity and diversity, skills and scale - - - EUR 1 999 761 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Considerable attention goes to ‘smart’ urban food procurement, with little notice of the cultural diversity within Europe. For a growing urban population (80% by 2050), food is a mediator of relations within social networks, - not only a commodity or nutrient. Eaters are not just consumers but social actors whose meaning-making depend on faith, gender, age, income, or kinship. How we procure and share food is thus central to cultural understandings of citizenship: the - project studies in-depth nine cases of collective food procurement across three European cities, asking if collective food procurement networks indicate emerging forms of ‘food citizenship’, or if they concomitantly co-produce hegemonic notions of - participation and belonging – and either way, how. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - FOOD CITIZENS - - - ERC-2016-COG - - - 724151 - - - - - UNIVERSITY OF GLASGOW - UNIVERSITY OF GLASGOW - THE UNIVERSITY OF MANCHESTER - - - EUR 3 005 817,75 - - - Game-changing Precision Medicine for Curing All Myeloproliferative Neoplasms - - - EUR 3 005 817,75 - - - United Kingdom - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Despite decades of research, developing ways to overcome drug resistance in cancer is the most challenging bottleneck for curative therapies. This is because, in some forms of cancer, the cancer stem cells from which the - diseases arise are constantly evolving, particularly under the selective pressures of drug therapies, in order to survive. The events leading to drug resistance can occur within one or more individual cancer stem cell(s) – and the features of each of - these cells need to be studied in detail in order to develop drugs or drug combinations that can eradicate all of them. The BCR-ABL+ and BCR-ABL- myeloproliferative neoplasms (MPN) are a group of proliferative blood diseases that can be considered - both exemplars of precision medicine and of the drug resistance bottleneck. While significant advances in the management of MPN have been made using life-long and expensive tyrosine kinase inhibitors (TKI), patients are rarely cured of their disease. - This is because TKI fail to eradicate the leukaemia stem cells (LSC) from which MPN arise and which persist in patients on treatment, often leading to pervasive drug resistance, loss of response to therapy and progression to fatal forms of acute - leukaemia. My goal is to change the way we study the LSC that persist in MPN patients as a means of delivering more effective precision medicine in MPN that is a “game-changer” leading to therapy-free remission (TFR) and cure. Here, I will apply an - innovative strategy, ChAMPioN, to study the response of the MPN LSC to TKI in innovative pre-clinical laboratory models and directly in patients with MPN - up to the resolution of individual LSC. This work will reveal, for the first time, the - molecular and clonal evolution of LSC during TKI therapies, thus enabling the development of more accurate predictions of TKI efficacy and resistance and rational approaches for curative drug therapies. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - ChAMPioN - - - ERC-2016-ADG - - - 742349 - - - - - UNIVERSITY OF HULL - UNIVERSITY OF HULL - - - EUR 2 581 155 - - - Morphodynamic Stickiness: the influence of physical and biological cohesion in sedimentary systems - - - EUR 2 581 155 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Our coasts, estuaries, & low-land river environments are some of the most sensitive systems to sea-level rise & environmental change. In order to manage these systems, & adapt to future changes, we desperately need - to be able to predict how they will alter under various scenarios. However, our models for these environments are not yet robust enough to predict, with confidence, very far into the future. Moreover, we also need to improve how we use our - understanding of modern environments in reconstructing paleo-environments, where significant assumptions have been made in the way in which relationships derived from the modern have been applied to ancient rocks. - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - GEOSTICK - - - ERC-2016-COG - - - 725955 - - - - - THE UNIVERSITY OF EDINBURGH - THE UNIVERSITY OF EDINBURGH - KING'S COLLEGE LONDON - PUBLIC HEALTH FOUNDATION OF INDIA - - - EUR 1 479 558 - - - Investigating the Design and Use of Diagnostic Devices in Global Health - - - EUR 1 479 558 - - - United Kingdom - United Kingdom - United Kingdom - India - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - Many people living in resource-poor settings have never had access to the laboratory facilities or technical expertise that are needed to diagnose diseases. With the development and deployment of a new generation of - affordable, easy-to-use, and portable diagnostic devices that are designed for places with no laboratory infrastructure, the global landscape of diagnosis is dramatically changing. Can portable diagnostic devices strengthen health systems in - resource-poor settings? DiaDev is the first study to comprehensively address this question through comparison across multiple devices, sites of production, and contexts of use. Diagnostic technologies are often championed as universal solutions to - health equity and access. This ethnographic study investigates the extent to which how diagnostic devices work and what they can achieve depends on the locally specific relationships through which they are designed and used. Five ethnographic case - studies from the USA, India and Sierra Leone examine the partnerships between donors, governments, humanitarian organisations and users that characterise current models of technological innovation and implementation in global health, the processes by - which diagnostic devices are integrated with health infrastructures in target settings, and the practices of knowledge production and use they entail. The ultimate aim is to generate new insight into (i) changing relationships of power between - governments, donors, and business in global health, and (ii) the ways in which diagnostic devices are transforming health systems in resource-poor settings. It will produce a new context-specific and comparative framework for exploring the - opportunities and challenges involved in the design and use of diagnostic devices. Through innovative collaborative methods it will also develop a set of ‘health system strengthening tools’ that will enable stakeholders to improve the design and use - of these devices in dialogue with the project findings. - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - DiaDev - - - ERC-2016-STG - - - 715450 - - - - - JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN - JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN - - - EUR 2 500 000 - - - Dissecting and targeting ubiquitin networks in the course of bacterial infections - - - EUR 2 500 000 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Ubiquitination represents one of the most versatile post-translational modifications in eukaryotes and is involved in regulation of numerous cellular processes. Despite prokaryotes lacking this system, facultative - intracellular bacteria like Salmonella, Shigella and Legionella have evolved multiple strategies to manipulate the host ubiquitin (Ub) system to their own benefit. This proposal is focussed on gaining a fundamental understanding of the Ub system in - the course of bacterial infections. We will employ advanced quantitative proteomics to perform a global analysis of the dynamic changes in the ubiquitinome and phosphoproteome of epithelial cells and macrophages upon infection with Salmonella, - Shigella and Legionella. The comprehensive datasets will constitute an invaluable resource freely available to the scientific community. We expect to identify novel pathways triggered by selected bacterial ligases and will characterise their - contribution to pathogenicity and virulence, as well as their suitability for being targeted in a therapeutic setting. Both medicinal chemistry and structural biology approaches will be exploited to identify inhibitors for NEL-type bacterial ligases. - Hypothesis-driven projects within the work program focus on (i) a novel chemical modification of Ub controlling Legionella infections and (ii) the observation that Ub chains on Salmonella can form nanoscale clusters that recruit and activate multiple - signalling pathways within the host cell. Super-resolution microscopy and single-molecule imaging will be used to visualise and dissect these Ub-triggered complexes. - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - Ub-BAC - - - ERC-2016-ADG - - - 742720 - - - - - UNIVERSITY OF BRISTOL - UNIVERSITY OF BRISTOL - - - EUR 1 778 516 - - - Log Correlations and Random Matrices - - - EUR 1 778 516 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Random Matrix Theory has been of central importance in Mathematical Physics for over 50 years. It has deep connections with many other areas of Mathematics and a remarkably wide range of applications. In 2012, a new avenue of - research was initiated linking Random Matrix Theory to the highly active area of Probability Theory concerned with the extreme values of logarithmically correlated Gaussian fields, such as the branching random walk and the two-dimensional Gaussian - Free Field. This connects the extreme value statistics of the characteristic polynomials of random matrices asymptotically to those of the Gaussian fields in question, allowing some important and long-standing open questions to be addressed for the - first time. It has led to a flurry of activity and significant progress towards proving some of the main conjectures. A remarkable discovery has been that the characteristic polynomials of random matrices exhibit, asymptotically, a hierarchical - branching/tree structure like that of the branching random walk. However, many of the most important questions remain open. My aim is to attack some of these problems using ideas and techniques that have so far not been applied to them: I believe it - is possible to compute some important statistical quantities relating to the extreme values of characteristic polynomials exactly, for the first time, by establishing connections with integrable systems, representation theory, and enumerative - combinatorics. Such connections have not previously been explored. I anticipate that this will have a significant impact on an area that is currently in a rapid phase of development and that it will settle some of the principal unresolved - conjectures. I further believe that ideas exploiting the hierarchical branching structure may have new and unexpected implications for areas connected with Random Matrix Theory, including, in particular, Number Theory, and I plan to explore these - too. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - LogCorRM - - - ERC-2016-ADG - - - 740900 - - - - - UNIVERSITAET LEIPZIG - UNIVERSITAET LEIPZIG - - - EUR 2 000 000 - - - Quantitative understanding of target recognition on DNA based on directional zipping processes - - - EUR 2 000 000 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In the recent years a number of protein systems have been identified that recognize long (tens of base pairs) DNA sequences and allow flexible programmability of their target specificity. This promoted an enormous range of - applications in genome engineering and synthetic biology. This project aims to decipher the mechanisms by which these proteins recognize their DNA targets in order to develop quantitative models/predictors for target recognition and to avoid - off-target effects. - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - ZIPgeting - - - ERC-2016-COG - - - 724863 - - - - - UNIVERSITEIT VAN AMSTERDAM - UNIVERSITEIT VAN AMSTERDAM - - - EUR 1 500 000 - - - An Empirical Foundation for Understanding Positive Emotions - - - EUR 1 500 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Positive emotions are of great importance for our physical and mental health and for our social relationships. However, scientific knowledge of positive emotions is lacking, with research to date being both fractionated and - scarce. The Positive Emotions Project (PEP) takes on the challenge of formulating a foundational, empirically-based framework of positive emotions. This is accomplished by a set of studies combining methodologies that examine both subjective and - objective elements of 17 positive emotions, including gratitude, awe, amusement, compassion, and relief. Central to the investigation is the integration of cross-cultural and developmental approaches, in order to differentiate between consistent - patterns and idiosyncratic features. Project 1 will use experience sampling to map out the experience of positive emotions across ten dramatically different cultures, examining subjective elements of emotions, such as antecedent events and - psychological states. Project 2 will comprehensively establish which nonverbal facial and vocal signals are associated with different positive emotions across cultures and ages. Project 3 will provide an integrated multi-level account of positive - emotions, considering similarities and differences across emotions, taking into account cross-cultural and developmental patterning of subjective and objective features. The empirical and theoretical results of PEP will result in new, innovative - paradigms, and substantial, freely available datasets that will help to redress the current dearth of data and approaches for understanding positive emotions. It will also provide the basis for a much-needed scientific, multifaceted account of - positive emotion. Such a model will benefit scientists across many disciplines, including affective computing, behavioural economics, and psychiatry, whose work builds on psychological models of emotions. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - PEP - - - ERC-2016-STG - - - 714977 - - - - - UNIVERSITY OF BRISTOL - UNIVERSITY OF BRISTOL - - - EUR 1 946 995 - - - Sound and Early Assessment of Leakage for Embedded Software - - - EUR 1 946 995 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Side channel attacks use, alongside information such as plaintexts or ciphertexts, leakage about the (secret) key-dependent intermediate state(s), and deliver a `key ranking' as a result. Kocher's attacks [15] [16] showed that - for many practical implementations, observing a few encryptions made complete key recovery possible in practice. The academic research into combating these attacks so far has largely focused on approaches and tools to equip specialised cryptographic - engineers with access to a specialist lab and tools. - - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - SEAL - - - ERC-2016-COG - - - 725042 - - - - - UNIVERSITEIT VAN AMSTERDAM - UNIVERSITEIT VAN AMSTERDAM - - - EUR 1 499 766 - - - Towards a neural and cognitive architecture of consciousness - - - EUR 1 499 766 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - For decades the cognitive neuroscience community has expended significant effort identifying system-level neural correlates of human consciousness, broad neural signatures that distinguish conscious from unconscious processes - at the level of whole brain regions. Meanwhile, within the field of neurobiology, rapid progress has been made in understanding the neurotransmitter systems underlying basic sensory processes (e.g. in mice, monkeys). This research has, however, been - performed in relative isolation from studies of human consciousness, and clear opportunities to link the two levels of description remain largely unexplored. Here I will establish this link by combining state-of-the-art neuroimaging techniques with - pharmacological interventions. - - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - CONSCIOUSNESS - - - ERC-2016-STG - - - 715605 - - - - - UNIVERSITY OF BRISTOL - UNIVERSITY OF BRISTOL - - - EUR 2 499 238 - - - Synthetic Cellularity via Protocell Design and Chemical Construction - - - EUR 2 499 238 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - We propose to undertake an ambitious 5-year multidisciplinary programme that seeks to pioneer and establish a fundamentally new paradigm in protolife research that is based on novel conceptual and experimental advances in the - design and construction of rudimentary forms of synthetic cell-like micro-ensembles (protocells). Our approach is positioned at the interface between materials chemistry, soft matter science and synthetic biology, and will address the following - aspects of protocell design and construction: (i) functional complexity in protocell phenotypes, (ii) protocell self-structuring and metamorphosis, (iii) multi-compartmentalization and protocell endosymbiosis, and (iv) collective behavior in - protocell communities. We will initiate unprecedented increases in the complexity of individual protocells by developing new types of structural architectures with advanced functions including photosynthetic protocells and motile proteinosomes, and - develop innovative strategies for the chemical secretion of spatially extended extra-protocellular hydrogel matrices and induction of protocell metamorphosis. We will develop a modular micro-engineering approach to protocell - multi-compartmentalization with the aim of generating coordinated enzyme- and gene-activated endosymbiotic interactions, and pioneer the experimental study of collective behaviour in communities of synthetic protocells. Our overall aim is to pioneer - a modern approach to synthetic cellularity that advances the chemical and physical basis of protocell structure and function, and spearheads the development of future technologies based on autonomously functioning chemical micro-compartments with - applications in bioinspired micro-storage and delivery, micro-reactor technologies, cytomimetic engineering, and the development of integrated constructs for diverse procedures in synthetic biology. - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - PCELLS - - - ERC-2016-ADG - - - 740235 - - - - - DIGITAL RESEARCH INFRASTRUCTURE FOR THE ARTS AND HUMANITIES - GEORG-AUGUST-UNIVERSITAT GOTTINGENSTIFTUNG OFFENTLICHEN RECHTS - UNIVERSITEIT GENT - UNIWERSYTET WARSZAWSKI - UNIVERSIDADE NOVA DE LISBOA - FACULDADE DE CIENCIAS SOCIAIS E HUMANAS DA UNIVERSIDADE NOVA DE LISBOA - CENTAR ZA DIGITALNE HUMANISTICKE NAUKE - GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER - INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE - KING'S COLLEGE LONDON - UNIVERSITY OF GLASGOW - KNIHOVNA AV CR V. V. I. - HELSINGIN YLIOPISTO - SWISS INSTITUTE OF BIOINFORMATICS - UNIVERSIDAD NACIONAL DE EDUCACION A DISTANCIA - UNIVERSITY OF HAIFA - - - EUR 2 717 320 - - - DARIAH ERIC Sustainability Refined - - - EUR 2 717 320 - - - France - Germany - Belgium - Poland - Portugal - Portugal - Serbia - Germany - France - United Kingdom - United Kingdom - Czech Republic - Finland - Switzerland - Spain - Israel - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Europe has a long and rich tradition as a centre for the arts and humanities. However, the digital transformation poses challenges to the arts and humanities research landscape all over the world. Responding to these - challenges the Digital Research Infrastructure for Arts and Humanities (DARIAH) was launched as a pan-European network and research infrastructure. After expansion and consolidation, which involved DARIAH’s inscription on the ESFRI roadmap, DARIAH - became a European Research Infrastructure Consortium (ERIC) in August 2014. - - 2019-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-03-2016-2017 - Individual support to ESFRI and other world-class research infrastructures - - - CSA - Coordination and support action - - - France - - - DESIR - - - H2020-INFRADEV-2016-1 - - - 731081 - - - - - UNIVERSITEIT VAN AMSTERDAM - UNIVERSITEIT VAN AMSTERDAM - - - EUR 1 300 775 - - - Non AdS holography and generalized geometric structures - - - EUR 1 300 775 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Holography is by now a fundamental tool in the understanding of both strongly coupled conformal field theories (CFTs) and quantum theories of gravity. While holography in Anti de Sitter (AdS) space-times is rather well - understood, we currently lack a basic picture of what it means in non-AdS space-times. Considering non-AdS space-times is an essential and urgent next step in the study of quantum gravity as we seem to live in a universe with a positive cosmological - constant that is approaching de Sitter (dS) in the far future. Also, the near-horizon geometries of black holes are typically described by more exotic geometries that need to be understood on their own right. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - GenGeoHol - - - ERC-2016-STG - - - 715656 - - - - - UNIVERSITEIT VAN AMSTERDAM - UNIVERSITEIT VAN AMSTERDAM - - - EUR 1 457 063 - - - Cognitive Semantics and Quantities - - - EUR 1 457 063 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - At the heart of the multi-faceted enterprise of formal semantics lies a simple yet powerful conception of meaning based on truth-conditions: one understands a sentence if one knows under which circumstances the sentence is - true. This notion has been extremely fruitful resulting in a wealth of practical applications. But to what extent can it also account for the human linguistic behavior? The past decade has seen the increasing interaction between cognitive science and - formal semantics, and the emergence of the new field of experimental semantics. One of its main challenges is the traditional normative take on meaning, which makes semantic theories hard to compare with experimental data. The aim of this project is - to advance experimental semantics by building cognitive semantics, that is semantics founded on cognitive representations instead of normative logical abstractions. - - 2022-01-31, ongoing project - - - 2017-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - CoSaQ - - - ERC-2016-STG - - - 716230 - - - - - LINKOPINGS UNIVERSITET - LINKOPINGS UNIVERSITET - - - EUR 2 000 000 - - - Predicting future methane fluxes from Northern lakes - - - EUR 2 000 000 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The new global temperature goal calls for reliable quantification of present and future greenhouse gas (GHG) emissions, including climate feedbacks. Non-CO2 GHGs, with methane (CH4) being the most important, represent a large - but highly uncertain component in global GHG budget. Lakes are among the largest natural sources of CH4 but our understanding of lake CH4 fluxes is rudimentary. Lake emissions are not yet routinely monitored, and coherent, spatially representative, - long-term datasets are rare which hamper accurate flux estimates and predictions. - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Sweden - - - METLAKE - - - ERC-2016-COG - - - 725546 - - - - - OBSERVATOIRE DE PARIS - ISTITUTO NAZIONALE DI RICERCA METROLOGICA - PHYSIKALISCH-TECHNISCHE BUNDESANSTALT - NPL MANAGEMENT LIMITED - GROUPEMENT D INTERET PUBLIC POUR LERESEAU NATIONAL DE TELECOMMUNICATIONS POUR LA TECHNOLOGIE L ENSEIGNEMENT ET LA RECHERCHE - CESNET ZAJMOVE SDRUZENI PRAVNICKYCH OSOB - INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK - UNIVERSITE PARIS 13 - MUQUANS - Menlo Systems GmbH - PIKTIME SYSTEMS SP ZOO - USTAV PRISTROJOVE TECHNIKY AVCR VVI - SEVEN SOLUTIONS SL - OPTOKON AS - AKADEMIA GORNICZO-HUTNICZA IM. STANISLAWA STASZICA W KRAKOWIE - UNIVERSITY COLLEGE LONDON - - - EUR 1 994 645 - - - CLOck NETwork Services: Strategy and innovation for clock services over optical-fibre networks - - - EUR 1 994 646,25 - - - France - Italy - Germany - United Kingdom - France - Czech Republic - Poland - France - France - Germany - Poland - Czech Republic - Spain - Czech Republic - Poland - United Kingdom - - - Higher or Secondary Education Establishments - Research Organisations - Paolo Antonio Mastroeni - Tel.: +39-011-3919541 - Fax: +39-011-346384 - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - "A scientific and technological paradigm change is taking place, concerning the way that very high performance time and frequency reference signals are distributed, moving from radio signal broadcasting to signal transport - over optical fibre networks. The latter technology demonstrates performance improvements by orders of magnitude, over distances up to continental scale. Research infrastructures are developing several related technologies, adapted to specific - projects and applications. - - - 2019-06-30, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.2.1."> - - - INFRAINNOV-02-2016 - Support to Technological Infrastructures - - - CSA - Coordination and support action - - - France - - - CLONETS - - - H2020-INFRAINNOV-2016-1 - - - 731107 - - - - - UNIVERSITE DE LIMOGES - BANGOR UNIVERSITY - IHP GMBH - INNOVATIONS FOR HIGH PERFORMANCE MICROELECTRONICS/LEIBNIZ-INSTITUT FUER INNOVATIVE MIKROELEKTRONIK - AGENZIA NAZIONALE PER LE NUOVE TECNOLOGIE, L'ENERGIA E LO SVILUPPO ECONOMICO SOSTENIBILE - UNIVERSITA DEGLI STUDI DI PADOVA - CREO MEDICAL LIMITED - - - EUR 3 978 517,50 - - - Semiconductor-based Ultrawideband Micromanipulation of CAncer STEm Cells - - - EUR 3 978 517,50 - - - France - United Kingdom - Germany - Italy - Italy - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - SUMCASTEC explores radically new approach for cancer stem cells (CSCs) real time isolation (i.e. within minutes vs current 40 days) and neutralization. A novel micro-optofluidic lab-on-chip (LOC) platform will be developed - through a joint and iterative effort by biologists, clinicians and engineers. For the first time, a single LOC will be capable of delivering ultra-wide broadband radiation to compare cell spectral signatures, image subcellular features, and hence - modulate CSCs microenvironment conditions with unprecedented space and time resolution. It will be driven to isolate CSCs from heterogeneous differentiated and stem cell populations, and force CSCs differentiation, ultimately inducing sensitivity to - anticancer treatments. Extensive in vitro and in vivo testing along with biophysical modelling will validate the approach and establish the proof-of-principle within the project life-time, while laying the groundwork for further development of future - electrosurgical tools that will be capable CSCs neutralization in tissue. - - - 2020-06-30, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-01-2016-2017 - FET-Open research and innovation actions - - - RIA - Research and Innovation action - - - France - - - SUMCASTEC - - - H2020-FETOPEN-1-2016-2017 - - - 737164 - - - - - FUNDACION IMDEA NANOCIENCIA - SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI DI TRIESTE - SERVICIO DE SALUD DE CASTILLA LA MANCHA - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - Mfd-diagnostics GmbH - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 3 752 057,50 - - - Towards an active bypass for neural reconnection - - - EUR 3 752 057,50 - - - Spain - Italy - Spain - France - Germany - Spain - - - Research Organisations - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - - ByAxon is devoted to the development of a new generation of sensors and electrodes based on nanotechnology materials for neural interfacing. We aim to design and build a prototype of an active implant that could work directly - at the spinal cord (SC) level. This implant will be primary focused on restoring the transmission of electrical signals in the injured SC, acting as an active local bypass, something not possible with current technology. Further applications might - include deep brain stimulation or retinal implants, among others. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-01-2016-2017 - FET-Open research and innovation actions - - - RIA - Research and Innovation action - - - Spain - - - ByAxon - - - H2020-FETOPEN-1-2016-2017 - - - 737116 - - - - - AGENZIA NAZIONALE PER LE NUOVE TECNOLOGIE, L'ENERGIA E LO SVILUPPO ECONOMICO SOSTENIBILE - INSTITUTO NACIONAL DE SAUDE DR. RICARDO JORGE - INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU BIORESURSE ALIMENTARE - FUNDACION CIDETEC - UNIVERSITE DE PAU ET DES PAYS DE L'ADOUR - ARISTOTELIO PANEPISTIMIO THESSALONIKIS - CESKA ZEMEDELSKA UNIVERZITA V PRAZE - SZEGEDI TUDOMANYEGYETEM - Finnish Food Safety Authority Evira - RIJKSINSTITUUT VOOR VOLKSGEZONDHEID EN MILIEU - TECHNISCHE UNIVERSITAET MUENCHEN - INSTITUT JOZEF STEFAN - J.Z.U. INSTITUT ZA JAVNO ZDRAVJE NA REPUBLIKA MAKEDONIJA SKOPJE - INSTITUT SCIENTIFIQUE DE SANTE PUBLIQUE - TURKIYE BILIMSEL VE TEKNOLOJIK ARASTIRMA KURUMU - FUNDATIA DAS - PENTRU O MOLDOVA BAZATA PE CUNOASTERE - PREMOTEC GMBH - - - EUR 1 959 537,75 - - - Progressing towards the construction of METROFOOD-RI - - - EUR 1 959 538,25 - - - Italy - Portugal - Romania - Spain - France - Greece - Czech Republic - Hungary - Finland - Netherlands - Germany - Slovenia - Former Yugoslav Republic of Macedonia - Belgium - Turkey - Moldova - Switzerland - - - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The general objective of PRO-METROFOOD is to bring the emerging METROFOOD-RI ESFRI project to the level of maturity required for entering in the active project list, strengthening the Consortium and planning the future phases. - The specific objectives have been set up in close relationship with the “ESFRI SWG & IG Recommendation”. 4 specific objectives have been identified: OBJ1 – design strategies on the medium and long terms; OBJ2 – provide the organizational - framework of METROFOOD-RI; OBJ3 – demonstrate the capability of METROFOOD-RI to supply scientific services and prepare the chart of services; OBJ4 – establish plans to coherently integrate METROFOOD-RI into the European landscape, realising - coordination with EU and National initiatives and positioning at a global level. The strategic Plan will be tailored to the Pan European Infrastructure current and envisaged capabilities, market opportunities and business needs. It will be developed - by involving funding agencies, relevant authorities supporting METROFOOD-RI and other stakeholders. A management conceptual model will be developed and the framework will be designed under operational, strategic and institutional aspects. Management - procedures suitable for the different phases will set up, so to cover short and long-term goals. A Quality Documentation System (QDS) will be developed and a data management plan (DMP) will be defined. In order to demonstrate the capability of - PRO-METROFOOD to supply services and to test its inter-operability, pilot services will be performed. In strict accordance with the METROFOOD-RI strategies, plans to coherently integrate METROFOOD-RI into the European landscape will be developed. A - Communication plan and education and training programmes will be developed for the different phases of METROFOOD-RI realization (earl, preparatory, implementation and operational phases). For each phase the main coordinator, the target group and the - main training subject areas will be specified. - - 2017-12-31, closed project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-02-2016 - Preparatory Phase and support to early phase of ESFRI projects - - - RIA - Research and Innovation action - - - Italy - - - PRO-METROFOOD - - - H2020-INFRADEV-2016-2 - - - 739568 - - - - - UNIVERSITY OF BRISTOL - UNIVERSITY COLLEGE LONDON - STICHTING KATHOLIEKE UNIVERSITEIT - UNIVERSITY OF LIMERICK - - - EUR 2 886 323,75 - - - Magnetic Control of Polymorphism in Pharmaceutical Compounds - - - EUR 2 886 323,75 - - - United Kingdom - United Kingdom - Netherlands - Ireland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This H2020-FETOPEN-2016-2017 proposal initiates a major international effort to direct polymorphism in pharmaceutical compounds through crystallizing in high magnetic fields. The ability to direct polymorphism would have a - transformative effect on almost all pharmaceutical compounds, and hence on society. - - 2019-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-01-2016-2017 - FET-Open research and innovation actions - - - RIA - Research and Innovation action - - - United Kingdom - - - MagnaPharm - - - H2020-FETOPEN-1-2016-2017 - - - 736899 - - - - - PROTOBIOS OU - TARTU ULIKOOL - SIHTASUTUS TARTU ULIKOOLI KLIINIKUM - TALLINNA TEHNIKAULIKOOL - KING'S COLLEGE LONDON - HELSINGIN YLIOPISTO - HELSINGIN JA UUDENMAAN SAIRAANHOITOPIIRIN KUNTAYHTYMÄ - ELVESYS SAS - OU QURETEC - - - EUR 1 305 000 - - - Towards Early Molecular Diagnostics of Schizophrenia - - - EUR 1 305 000 - - - Estonia - Estonia - Estonia - Estonia - United Kingdom - Finland - Finland - France - Estonia - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Schizophrenia (SZ) is a severe mental disorder affecting more than 0.7% of the adult population. One of the most disabling and emotionally devastating illnesses known to man, SZ is also associated with considerable - socioeconomic burden. In general, the chronic nature and the high degree of patient disability make SZ the fourth leading cause of disease burden across the globe with the management costs making up ~3% of the total healthcare budget in the Western - countries. The situation is even direr in some regions, including northern Sweden and Finland, where relative prevalence of SZ exceeds two to three times corresponding national or regional averages. Poorly understood aetiology and limited diagnostic - arsenal make it difficult to detect and treat SZ in a timely and efficient manner. This underscores a critical need for better understanding of the mechanisms underlying SZ and development of new diagnostic possibilities allowing its early detection, - ideally prior to the onset of psychosis. The SZ_TEST will address these challenges by coordinating efforts with complementary areas of expertise in genetics, epigenetics, neurodevelopment, molecular psychiatry, clinical immunology and biotech - R&D. The overarching hypothesis underlying our work is that genetic vulnerabilities, neurodevelopmental defects, exposure to pathogens, immune system status and specific lifestyle choices may compound the risk of SZ and that a systematic - multivariate analysis of these factors should result in substantially improved diagnostic tools. SZ_TEST will work towards the development of molecular diagnostics tools for early detection of SZ, by using relevant cohorts of human subjects, unique - animal and cell models, and combining unbiased high-throughput omic screens with knowledge-based candidate marker analyses. SZ_TEST training network is expected to have a major impact on improving the quality of life and reducing the health care - costs in Europe and worldwide. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Estonia - - - SZ_TEST - - - H2020-MSCA-RISE-2016 - - - 734791 - - - - - STICHTING VU - KING'S COLLEGE LONDON - GOETEBORGS UNIVERSITET - UNIVERSITY OF BRISTOL - ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM - KAROLINSKA INSTITUTET - UNIVERSITEIT TWENTE - UNIVERSITA DEGLI STUDI DI CAGLIARI - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - JANSSEN-CILAG AKTIEBOLAG - - - EUR 3 163 687,92 - - - Childhood and Adolescence Psychopathology: unravelling the complex etiology by a large Interdisciplinary Collaboration in Europe - - - EUR 3 163 687,92 - - - Netherlands - United Kingdom - Sweden - United Kingdom - Netherlands - Sweden - Netherlands - Italy - United Kingdom - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - In the Roadmap for Mental Health and Wellbeing Research in Europe (ROAMER), top-priority is research into child and adolescent mental health symptoms. CAPICE (Childhood and Adolescence Psychopathology: unravelling the complex - etiology by a large Interdisciplinary Collaboration in Europe) will address this priority. - - - 2021-01-31, ongoing project - - - 2017-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Netherlands - - - CAPICE - - - H2020-MSCA-ITN-2016 - - - 721567 - - - - - ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM - UNIVERSITY OF LEICESTER - UNIVERSITAETSMEDIZIN GOETTINGEN - GEORG-AUGUST-UNIVERSITAET GOETTINGEN - STIFTUNG OEFFENTLICHEN RECHTS - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - ECOLE NORMALE SUPERIEURE - UNIVERSIDAD DE SALAMANCA - KING'S COLLEGE LONDON - UNIVERSITAETSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITAET MAINZ - - - EUR 2 584 755,72 - - - Liaison in Scientific Training for European auditory Neuroscience - - - EUR 2 584 755,72 - - - Netherlands - United Kingdom - Germany - France - France - Spain - United Kingdom - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This ITN will train 10 ESRs to meet the urgent need for translation of Auditory Neuroscience into commercial and pharmaceutical products to treat hearing disorders including tinnitus. Tinnitus is the debilitating perception of - imaginary sound that is often associated with hearing loss. This Liaison in Scientific Training for European auditory Neuroscience (LISTEN) is a consortium of top hearing scientists in industry and academia, who specialize in hearing mechanisms and - translation to commercial applications, enabling broad career opportunities for our ESRs. The multidisciplinary training environment includes leading labs and companies from 7 EU states, specialized in research, drug and instrumental development. - Hearing is vulnerable to noise trauma, medication and aging, and in the future hearing loss will be one of the top ten disease burdens for Europe. Europe must rapidly exploit academic knowledge to invest in treatments for hearing disorders including - drug development. Young scientists entering this field must acquire a broad and detailed background in neuroscience, acoustics, biophysics and signal processing, and employ genetic, molecular, pharmacology, anatomy and imaging methods. No single - European institute can encompass this, but together, our LISTEN network will enable young scientists and entrepreneurs to unravel hearing mechanisms and design the next-generation of treatments. Work Package 1 (WP1) focuses on neural coding of sounds - from the cochlea to neocortex, including auditory processing for localizing sounds and complex cognitive tasks in both normal hearing and following hearing loss. WP2 will identify molecular and genetic mechanisms of the hyperexcitability underlying - tinnitus, exploit new techniques for monitoring tinnitus and develop new drug therapies. Integration of the WPs will enable new insights into disease mechanisms and WP3 will provide the ESRs with an essential multidisciplinary background for their - research and successful careers. - - 2020-11-30, ongoing project - - - 2016-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Netherlands - - - LISTEN - - - H2020-MSCA-ITN-2016 - - - 722098 - - - - - UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA - UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA - - - EUR 150 000 - - - Evaluation of commercial potential of a low-cost kit based on DNA-nanoswitches for the single-step measurement of diagnostic antibodies - - - EUR 150 000 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - "Antibodies are among the most widely monitored class of diagnostic biomarkers. Immunoassays market now covers about 1/3 of the global market of in-vitro diagnostics (about $50 billion). However, current methods for the - detection of diagnostic antibodies are either qualitative or require cumbersome, resource-intensive laboratory procedures that need hours to provide clinicians with diagnostic information. A new method for fast and low-cost detection of antibodies - will have a strong economic impact in the market of in-vitro diagnostics and Immunoassays. - - 2018-07-31, ongoing project - - - 2017-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Italy - - - AB-SWITCH - - - ERC-2016-PoC - - - 727313 - - - - - UNIVERSITEIT VAN AMSTERDAM - UNIVERSITEIT VAN AMSTERDAM - - - EUR 1 926 634 - - - The Impact of Massive Binaries Through Cosmic Time - - - EUR 1 926 634 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Massive stars play many key roles in Astrophysics. As COSMIC ENGINES they transformed the pristine Universe left after the Big Bang into our modern Universe. We use massive stars, their explosions and products as COSMIC PROBES - to study the conditions in the distant Universe and the extreme physics inaccessible at earth. Models of massive stars are thus widely applied. A central common assumption is that massive stars are non-rotating single objects, in stark contrast with - new data. Recent studies show that majority (70% according to our data) will experience severe interaction with a companion (Sana, de Mink et al. Science 2012). - - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - BinCosmos - - - ERC-2016-STG - - - 714063 - - - - - UNIVERSITY OF HULL - MUNTERS EUROPE AB - INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK - DATA CENTRE ALLIANCE LIMITED - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - NPS HUMBER LIMITED - HISENSE GERMANY GMBH - APPLIED INDUSTRIAL TECHNOLOGIES LTD - - - EUR 1 156 500 - - - Low Energy Dew Point Cooling for Computing Data Centres - - - EUR 1 845 000 - - - United Kingdom - Sweden - Poland - United Kingdom - France - United Kingdom - Germany - Greece - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Cooling systems for Computing & Data Centres consume 30% to 40% of energy delivered into the centre spaces, while electricity use in CDCs represents 1.3% of the world total energy consumption. The traditional vapour - compression cooling systems for CDCs are neither energy efficient nor environmentally friendly. Several alternative cooling systems, e.g., adsorption/absorption, ejector, and evaporative types, have certain level of energy saving potential but - exhibit some inherent problems that have restricted their wide applications in CDCs. This RISE programme aims to form an international and inter-sectoral network of organisations working on a joint research and innovation programme dedicated to - develop the design theory, computerised tool and technology prototypes for a novel CDC dew point cooling system. Such a system, comprising a few critical and highly innovative components (i.e., dew point air cooler, adsorbent sorption/regeneration - cycle, micro-channels-loop-heat-pipe (MCLHP) based CDC heat recovery system, paraffin/expanded-graphite based heat storage/exchanger, and internet-based intelligent monitoring and control system), is expected to achieve 60% to 90% of electrical - energy saving and have a comparable initial price to traditional CDC air conditioning systems, thus removing the above outstanding problems remaining with existing CDC cooling systems. Within the programme, the participants will exchange skills and - knowledge that will allow them to progress towards the key target set for the CDC dew point cooling system, and strengthen collaborative research among different countries and sectors. The advances in the novel CDC dew point cooling system will have - potential market opportunities for non-academic participants in the programme, and have significant benefits to European society and economy. The staff members who participate in the programme will develop new skills, be exposed to new research - environments and have their career perspectives widened. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - United Kingdom - - - DEW-COOL-4-CDC - - - H2020-MSCA-RISE-2016 - - - 734340 - - - - - UNIVERSITA DEGLI STUDI DI TERAMO - UNIVERSITA DEGLI STUDI DI CAGLIARI - UNIVERSIDAD DE BURGOS - AVANTEA srl - BIOTALENTUM TUDASFEJLESZTO KFT - IMAGENE - BIOBANKS AND BIOMOLECULAR RESOURCES RESEARCH INFRASTRUCTURE CONSORTIUM (BBMRI-ERIC) - UNIVERSITA DEGLI STUDI DI MODENA E REGGIO EMILIA - - - EUR 765 000 - - - Setting an interdisciplinary/sectorial/international research network to explore dry storage as an alternative strategy for cells/germplasm biobanking - - - EUR 841 500 - - - Italy - Italy - Spain - Italy - Hungary - France - Austria - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - - The number of biobanks for diagnostic/clinical/biodiversity preservation purposes is increasing exponentially, representing an economic burden for the EU. Cryopreservation (Liquid Nitrogen LN) is the only cells/gametes - long-term repository method. LN storage is expensive though, requires dedicated facilities, is hazardous, carries pathogens and has high carbon footprint. DRYNET objective is to set an inter-sectorial/multidisciplinary/international network between - EU academic (5), SME (3), the EU pan-Biobank, and international partners (Japan/Thailand), with the aim of sharing knowhow & expertise to lay down the theoretical and early empirical basis for the dry storage of cells/germplasm. DRYNET merges the - partner’s expertise, theoretical/ biophysical/ mathematical modelling, cellular/ molecular/ insect biology, embryology, mechanical engineering into a coherent approach towards dry storage of cells/germplasm. International/inter-sectorial secondments, - with meeting/workshop/summer school will be primary tools to implement our strategy for biobanking. Outreaching activities will guarantee public awareness of the project. DRYNET’s relies on water subtraction to induce a reversible block of - metabolism, a survival strategy available in nature (anhydrobiosis). The work plan foresees the exploitation of natural xero-protectants (Late Embryogenesis Abundant proteins), loaded/expressed in gametes/cells, before drying. The best drying - approaches, supported by theoretical/biophysical/math modelling, will be implemented by SMEs/academy partners. DRYNET will bring a simplification of currents practices, with cost and carbon footprint reduction, for the maintenance/shipping of - biobanks. DRYNET will generate young scientists with transferable skills, ensuring career prospect in academia/industry. DRYNET strengthens the international/sectorial network between different disciplines, ensures long-term sustainability of the - project, and boosts European competitiveness in biobanking. - - 2021-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Italy - - - DRYNET - - - H2020-MSCA-RISE-2016 - - - 734434 - - - - - UNIVERSITEIT VAN AMSTERDAM - UNIVERSITEIT VAN AMSTERDAM - - - EUR 1 465 097 - - - Fast and efficient sponge engines drive and modulate the food web of reef ecosystems - - - EUR 1 465 097 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Coral reefs are iconic examples of biological hotspots, highly appreciated because of their ecosystem services. Yet, they are threatened by human impact and climate change, highlighting the need to develop tools and strategies - to curtail changes in these ecosystems. Remarkably, ever since Darwin’s descriptions of coral reefs, it has been a mystery how one of Earth’s most productive and diverse ecosystems thrives in oligotrophic seas, as an oasis in a marine desert. My team - recently discovered the ‘sponge loop’ pathway (Science, De Goeij et al 2013) that efficiently retains and transfers energy and nutrients on the reef. We recognized sponges as potential (and so far neglected) key ecosystem drivers, and accumulated - evidence on sponge loops in other ecosystems, such as deep-sea coral reefs. As a result, current reef food web models, lacking sponge-driven resource cycling, are incomplete and need to be redeveloped. However, mechanisms that determine the capacity - of sponge 'engines', how they are fuelled, and drive communities are unknown. - - - 2021-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - SPONGE ENGINE - - - ERC-2016-STG - - - 715513 - - - - - UNIVERSITY OF BRISTOL - UNIVERSITY OF BRISTOL - - - EUR 1 809 752 - - - High-Pressure High-Temperature Superconductivity - - - EUR 1 809 752 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Superconductors promote electrical currents without loss and are exploited for applications like magnets in medical imaging. Further applications like large scale usage in electrical power generation and transmission, however, - are limited by the need to cool materials below a critical temperature Tc. Thus, novel superconductors with higher Tc are highly desirable. - - 2022-01-31, ongoing project - - - 2017-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - HPSuper - - - ERC-2016-STG - - - 715262 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - UNIVERSITA CA' FOSCARI VENEZIA - CHALMERS TEKNISKA HOEGSKOLA AB - UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6 - UNIVERSITE PARIS DIDEROT - PARIS 7 - VRIJE UNIVERSITEIT BRUSSEL - UNIVERSITEIT VAN AMSTERDAM - UNIVERSITAET LEIPZIG - - - EUR 5 817 276,25 - - - Opinion Dynamics and Cultural Conflict in European Spaces - - - EUR 5 817 276,25 - - - Germany - Italy - Sweden - France - France - Belgium - Netherlands - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Social media and the digitization of news and discussion fora are having far-reaching effects on the way individuals and communities communicate, organize, and express themselves. Can the information circulating on these - platforms be tapped to better understand and analyze the enormous problems facing our contemporary society? Could this help us to better monitor the growing number of social crises due to cultural differences and diverging world-views? Would this - facilitate early detection and perhaps even ways to resolve conflicts before they lead to violence? The Odycceus project answers all these questions affirmatively. It will develop the conceptual foundations, methodologies, and tools to translate this - bold vision into reality and demonstrate its power in a large number of cases. - - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.2."> - - - FETPROACT-01-2016 - FET Proactive: emerging themes and communities - - - RIA - Research and Innovation action - - - Germany - - - ODYCCEUS - - - FETPROACT-2016 - - - 732942 - - - - - UNIVERSITY OF BRISTOL - UNIVERSITY OF BRISTOL - - - EUR 149 918 - - - Quaternary Amino Acids on Scale for Medicine and Agroscience - - - EUR 149 918 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Enantiopure quaternary amino acids, carrying two carbon-based substituents at the α carbon, are one of the most important groups of modified α amino acids, of great commercial value in the development of new pharmaceuticals - and agrochemicals. Certain of these quaternary amino acids are readily available by stereoselective α alkylation of available amino acids, but not those functionalized by the addition of α-aryl groups. In this project, we propose to develop an - industrially scalable, practical method for the synthesis of α-arylated quaternary amino acids in enantiomerically pure form by streamlining, optimization and scale-up of a reaction we discovered while working on the synthesis of quaternary amino - acids as conformational controllers within an ERC-funded Advanced Grant. The method is operationally simple and employs only inexpensive commodity chemicals as precursors. It uses no chiral auxiliary or catalyst, and exploits both structure and - stereochemistry of the starting amino acid to make the quaternary amino acids in enantiomerically pure form. It avoid the use of transition metals, freeing the method from the potential problems associated with their toxicity, cost and volatility of - supply. The nearest competitive methods are either limited in scope to electron-deficient aryl rings, or they employ toxic and expensive transition metal catalysts. Interest in the method has been garnered from the fine chemical, pharmaceutical and - agrochemical industry, but further work on scale-up and practical issues are needed for the technology to become industry-ready. - - 2018-04-30, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - QUATERMAIN - - - ERC-2016-PoC - - - 727296 - - - - - UNIVERSITA DEGLI STUDI DI MILANO - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSITY OF NEWCASTLE UPON TYNE - UNIVERSITE CATHOLIQUE DE LOUVAIN - UNIVERSITEIT VAN AMSTERDAM - THE UNIVERSITY OF BIRMINGHAM - UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II. - AICURIS ANTI-INFECTIVE CURES GMBH - ANTIBIOTX APS - BIOVERSYS AG - NAICONS SRL - - - EUR 3 931 378,20 - - - An integrated mulTidisciplinary appRoach towards a new generAtIon of aNtibiotics: Targeting function and cross-talk of bacterial Envelope proTein machineries - - - EUR 3 931 378,20 - - - Italy - France - United Kingdom - Belgium - Netherlands - United Kingdom - Italy - Germany - Denmark - Switzerland - Italy - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Train2Target is a multidisciplinary European Training Network built to address the challenge of the discovery of alternative antimicrobials. Innovative strategies to deliver a next generation of drugs are urgently needed. The - alarming threats and spread of multi-drug resistant bacteria is currently leaving clinicians with very limited options to combat infections especially those from Gram-negative pathogens. - - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Italy - - - Train2Target - - - H2020-MSCA-ITN-2016 - - - 721484 - - - - - STICHTING ASTRON, NETHERLANDS INSTITUTE FOR RADIO ASTRONOMY - THE UNIVERSITY OF MANCHESTER - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - ISTITUTO NAZIONALE DI ASTROFISICA - CHALMERS TEKNISKA HOEGSKOLA AB - GEANT LIMITED - STICHTING EGI - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - FORSCHUNGSZENTRUM JULICH GMBH - SKA ORGANISATION - SCIENCE AND TECHNOLOGY FACILITIES COUNCIL - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - INSTITUTO DE TELECOMUNICACOES - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - ETHNIKO DIKTYO EREVNAS TECHNOLOGIAS AE - STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN - JOINT INSTITUTE FOR VERY LONG BASELINE INTERFEROMETRY AS A EUROPEAN RESEARCH INFRASTRUCTURE CONSORTIUM (JIV-ERIC) - STICHTING INTERNATIONAL LOFAR TELESCOPE - UPPSALA UNIVERSITET - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - UNIVERSITE DE GENEVE - COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION - AARNET PTY LTD - THE RESEARCH TRUST OF VICTORIA UNIVERSITY OF WELLINGTON - COUNCIL FOR SCIENTIFIC AND INDUSTRIAL RESEARCH - UNIVERSITY OF CAPE TOWN - NATIONAL RESEARCH FOUNDATION - RESEARCH DATA ALLIANCE FOUNDATION - - - EUR 2 999 995 - - - Advanced European Network of E-infrastructuresfor Astronomy with the SKA - - - EUR 2 999 995 - - - Netherlands - United Kingdom - United Kingdom - Italy - Sweden - United Kingdom - Netherlands - Germany - Germany - United Kingdom - United Kingdom - Spain - Portugal - France - Greece - Netherlands - Netherlands - Netherlands - Sweden - Switzerland - Switzerland - Australia - Australia - New Zealand - South Africa - South Africa - South Africa - United Kingdom - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Other - Other - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Other - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - - The objective of the AENEAS project is to develop a concept and design for a distributed, federated European Science Data Centre (ESDC) to support the astronomical community in achieving the scientific goals of the Square - Kilometre Array (SKA). The scientific potential of the SKA radio telescope is unprecedented and represents one of the highest priorities for the international scientific community. By the same token, the large scale, rate, and complexity of data the - SKA will generate, present challenges in data management, computing, and networking that are similarly world-leading. SKA Regional Centres (SRC) like the ESDC will be a vital resource to enable the community to take advantage of the scientific - potential of the SKA. Within the tiered SKA operational model, the SRCs will provide essential functionality which is not currently provisioned within the directly operated SKA facilities. AENEAS brings together all the European member states - currently part of the SKA project as well as potential future EU SKA national partners, the SKA Organisation itself, and a larger group of international partners including the two host countries Australia and South Africa. - - 2019-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.3.1., H2020-EU.1.4.1.3., H2020-EU.1.4.3.2."> - - - INFRASUPP-03-2016 - Support to policies and international cooperation for e-infrastructures - - - RIA - Research and Innovation action - - - Netherlands - - - AENEAS - - - H2020-INFRASUPP-2016-1 - - - 731016 - - - - - UNIVERSITETET I STAVANGER - UNIVERSITY OF LINCOLN - UNIVERSITEIT TWENTE - UNIVERSITAT AUTONOMA DE BARCELONA - LINKOPINGS UNIVERSITET - UNIVERSIDADE DE AVEIRO - AALBORG UNIVERSITET - COMUNIDADE INTERMUNICIPAL DA REGIAO DE AVEIRO - REGIO TWENTE - - - EUR 3 709 815,84 - - - The Role of Universities in Innovation and Regional Development - - - EUR 3 709 815,84 - - - Norway - United Kingdom - Netherlands - Spain - Sweden - Portugal - Denmark - Portugal - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - The Role of Universities in Innovation and Regional Development (RUNIN) is a European Training Network for Early-Stage Researchers (ESRs) in the field of science and innovation studies. The aim of the network is to train - researchers on how universities contribute to innovation and economic growth in their regions through research seeking to examine how universities fulfill their third mission in relation to regional industry and explore the range of university - engagement with regional firms and institutions. The project operationalises the main research question of how universities can contribute to innovation and regional development through four main themes: People and Networks, Policies and - Interventions, Places and Territories, and Practices and Governance. The aim of the training programme is to equip the next generation of researchers with the skills required to work across employment sectors, collaborate with a wide range of - stakeholders and find the practical relevance of their specialist knowledge, in the process creating new knowledge on universities’ role in innovation and regional development. There is an increased focus on the instrumentalist position of - universities as important drivers of regional development, and the aim of the training programme is therefore to equip a new generation of researchers who can work within this field in the academic world or as specialist policy makers at the - regional, national or European level. The programme will capitalise on host institutions’ infrastructure, including supervision, methods training and quality assurance review systems. In addition, it will offer a comprehensive programme of learning - through individual research projects, secondments, and eight targeted training events aimed at developing both research-specific and transferable skills. - - 2020-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Norway - - - RUNIN - - - H2020-MSCA-ITN-2016 - - - 722295 - - - - - UNIVERSITA DEGLI STUDI DI SALERNO - TECHNISCHE UNIVERSITEIT EINDHOVEN - FUNDACION TECNALIA RESEARCH & INNOVATION - ICI CALDAIE SPA - KT - KINETICS TECHNOLOGY SPA - L AIR LIQUIDE SA - - - EUR 688 500 - - - PROcess intensification through the development of innovative MEmbranes and CAtalysts - - - EUR 688 500 - - - Italy - Netherlands - Spain - Italy - Italy - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - PROMECA strategic objective is to substantially contribute to the increase of knowledge, skills, and competitiveness in the European research area and industry, through the design and deployment of a thorough plan of research - and secondment of researchers between top-level EU academia and industrial partners, contributing to the main European Policies on innovation. In line with the MSCA-RISE general objectives, the project will: - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Italy - - - PROMECA - - - H2020-MSCA-RISE-2016 - - - 734561 - - - - - OSLO UNIVERSITETSSYKEHUS HF - UNIVERSIDAD DE CORDOBA - NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU - UNIVERSITE PARIS 13 - CASCINATION AG - UNIVERSITAET BERN - INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE - STIFTELSEN SINTEF - TECHNISCHE UNIVERSITEIT DELFT - - - EUR 4 041 920,04 - - - High Performance Soft-tissue Navigation - - - EUR 4 041 920,04 - - - Norway - Spain - Norway - France - Switzerland - Switzerland - France - Norway - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - - Primary liver cancer, which consists predominantly of hepatocellular carcinoma (HCC), is the fifth most common cancer worldwide and the third most common cause of cancer mortality. A successful surgical resection of HCC - requires complete removal of the tumour while sparing as much healthy tissue as possible. Due to technical and clinical difficulties relatively low percentage of patients are eligible for resection. There is an urgent need to increase the patient - eligibility and improve the survival prognosis after liver interventions. HiPerNav will train early stage researchers (biomedical engineers and medical doctors) to become international leading in key areas of expertise through a novel coordinated - plan of individual research projects addressing specific bottlenecks in soft tissue navigation for improved treatment of liver cancer. The multi-disciplinary dialogue and work between clinicians and biomedical engineers is crucial to address these - bottlenecks. By providing researchers with knowledge and training within specific topics from minimally invasive treatment, biomedical engineering, research methodologies, innovation and entrepreneurship, the link between academic research and - industry will be strengthened. This allows for easy transfer of promising results from the research projects to commercially exploitable solutions. The global image guided surgery devices market is promising; it was valued at USD 2.76 billion in 2013 - and is projected to expand 6.4% from 2014 to 2022 to reach USD 4.80 billion in 2022. The market for soft-tissue navigation is still in its infancy, mainly due to challenges in achieved accuracy for targeting deformable and moving organs. By providing - multi-disciplinary training, the researchers in this consortium of international leading research institutions, universities and industry will initiate true translational research from academic theoretical ideas to the clinical testing of prototype, - developed solutions and tools. - - 2020-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Norway - - - HiPerNav - - - H2020-MSCA-ITN-2016 - - - 722068 - - - - - ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM - STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS - JUSTUS-LIEBIG-UNIVERSITAET GIESSEN - UNIVERSITY OF BRISTOL - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - MEDICAL RESEARCH COUNCIL - FUTURESYNTHESIS SP ZOO - ELVESYS SAS - - - EUR 3 097 183,68 - - - Regulated Assembly of Molecular Machines for DNA REPAIR: a Molecular Analysis training Network - - - EUR 3 097 183,68 - - - Netherlands - Netherlands - Germany - United Kingdom - France - United Kingdom - Poland - France - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The European Training Network DNAREPAIRMAN aims to train a new generation of innovative young scientists in cutting edge biophysical research methodology to address central questions in biology concerning the mode of action of - critical molecular machines with relevance for human health. The Network consists of a highly collaborative consortium consisting of 12 participants coming from academia, industry, and the creative sector. Participating laboratories in the Network - are part of established research schools within renowned research organizations and Universities, with supervisors who are experts within their respective research field, publish regularly in high-impact journals and have received EURYI and ERC - awards. This environment of excellence offers a multidisciplinary PhD program to 12 young researchers (ESRs), through training in the analysis of basic chemical and physical principles that underlie the correct timing and localization of events - during DNA repair. In addition training will center around method development using methodology, equipment, software and experience provided first-hand by four small technology-driven companies. Individual research projects as well as personal - training plans will be implemented for each ESR, incorporating a local training program, multiple rotations within partner laboratories, exposure to the non-academic sector and Network meetings. ESRs will follow scientific workshops, courses in - transferable skills, career development and entrepreneurship, and will disseminate and communicate their projects to a diverse audience in close collaboration with the creative sector. DNAREPAIRMAN will result in a new generation of mature and - innovative European scientists with a thorough understanding of fundamental quantitative principles underlying biology, with experience in technique development, and affinity for the academic as well as the non-academic research setting, providing a - broad and promising career perspective. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Netherlands - - - DNAREPAIRMAN - - - H2020-MSCA-ITN-2016 - - - 722433 - - - - - PSIQUADRO SOCIETA COOPERATIVA - EUROPEAN GRAVITATIONAL OBSERVATORY - ISTITUTO NAZIONALE DI FISICA NUCLEARE - UNIVERSITA DEGLI STUDI DI PERUGIA - UNIVERSITA POLITECNICA DELLE MARCHE - UNIVERSITA DEGLI STUDI DI PALERMO - OBSERVA - - - EUR 384 600 - - - SHAring Researchers’ Passion for Engagement and Responsibility - - - EUR 512 743,75 - - - Italy - Italy - Italy - Italy - Italy - Italy - Italy - - - Other - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - Researchers love to engage with nature, society, with future and ultimately with all the complex challenges that will allow them to contribute to a better world. Researchers also love to engage with other people to make the - quest they’re involved in a collective endeavour. All this make researchers persons passionate for engagement who are developing a growing sense of responsibility related to their work and their role in society. In such a professional life - researchers experience strong driving forces such as enthusiasm, emotions, combined with new knowledge and innovative discoveries. All these elements are summarized in the acronym SHARPER - Sharing Researchers’ Passion for Engagement and - Responsibility the name of the European Researchers’ Night in the Centre and South of Italy that will take place on the 30th of September 2016 and on the 29th of September 2017 simultaneously in five cities: Perugia, L’Aquila, Ancona and Palermo – - the four capital cities of the regions Marche, Umbria, Abruzzo, Sicily and in Cascina the city hosting the European Gravitational Observatory one of the cutting edge European research facilities. This network of cities combined with their Research - Institutions and with their social and cultural actors provides a team of excellence and reliability both in the fields of research and science communication at national and international level. The SHARPER project will create effective communication - bridges between researchers and the cities and communities they live and act within, through: street labs, exhibitions, performances in city squares or activities that will take place in focal city venues, where citizens use to spend their everyday - life. SHARPER 2016-2017 will geographically broaden the impact of the communication actions of European Researchers’ Night in Italy massively engaging kids, young students, schools, associations and citizens at large actively involved by researchers - since the planning phase of the activities. - - 2017-11-30, closed project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.5."> - - - MSCA-NIGHT-2016 - European Researchers' Night - - - CSA - Coordination and support action - - - Italy - - - SHARPER - - - H2020-MSCA-NIGHT-2016 - - - 722981 - - - - - UNIVERSITAET BIELEFELD - UNIVERSITEIT VAN AMSTERDAM - UNIVERSITE CATHOLIQUE DE LOUVAIN - UNIVERSITE PARIS I PANTHEON-SORBONNE - UNIVERSITA CA' FOSCARI VENEZIA - UNIVERSITA CATTOLICA DEL SACRO CUORE - UNIVERSITY OF SURREY - - - EUR 3 864 090,24 - - - Expectations and Social Influence Dynamics in Economics - - - EUR 3 864 090,24 - - - Germany - Netherlands - Belgium - France - Italy - Italy - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Expectations play a crucial role in determining the behaviour of many economic decision makers. The recent financial and economic crisis has highlighted the importance of expectation dynamics for economic development, the - success of firm strategies and public policies. The Innovative Training Network ExSIDE aims at improving our understanding of the role of expectation formation and social influence for economic dynamics and for the optimal design of economic policy. - - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-EJD - European Joint Doctorates - - - Germany - - - ExSIDE - - - H2020-MSCA-ITN-2016 - - - 721846 - - - - - KING'S COLLEGE LONDON - KING'S COLLEGE LONDON - - - EUR 1 427 361 - - - Particle-Surface Interactions in Near Field Optics: Spin-orbit Effects of Light and Optical/Casimir Forces - - - EUR 1 427 361 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - PSINFONI aims to open new avenues of research in ultrafast routing and polarization synthesis of light in nanophotonics, and in the manipulation, sorting, levitation and trapping of nanoparticles, molecules, or single atoms - near novel nanomaterial surfaces. To this end, we will explore the fundamentals and applications of a range of novel nanophotonic phenomena: (i) spin-orbit interactions of light for polarization-controlled optical routing and polarization synthesis - at the nanoscale; (ii) repulsive and switchable lateral optical forces on particles near engineered surfaces for optical manipulation and sorting; and (iii) Casimir repulsive and lateral forces for quantum levitation / frictionless nanomaterials. All - these diverse phenomena can be studied under the single framework of particle-surface interactions in the near field, greatly diversifying the research outcomes from a single research effort. Knowledge of the full 3D electromagnetic fields in - particle-surface systems will form the foundation from which to explore fundamental aspects and limitations of the above mentioned effects, opening new applications in information technologies and new nanomaterials. Proof of principle experimental - demonstrations will be performed where possible. - - 2022-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - PSINFONI - - - ERC-2016-STG - - - 714151 - - - - - FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA - UNIVERSITAT POLITECNICA DE CATALUNYA - LEIBNIZ-INSTITUT FUER NEUE MATERIALIEN GEMEINNUETZIGE GMBH - KING'S COLLEGE LONDON - UNIVERSITAIR MEDISCH CENTRUM UTRECHT - MIND THE BYTE SL - NOVIOCELL BV - - - EUR 7 134 928,75 - - - Mechanical control of biological function - - - EUR 7 134 928,75 - - - Spain - Spain - Germany - United Kingdom - Netherlands - Spain - Netherlands - - - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Mechanical forces transmitted through specific molecular bonds drive biological function, and their understanding and control hold an uncharted potential in oncology, regenerative medicine and biomaterial design. However, this - potential has not been realised, because it requires developing and integrating disparate technologies to measure and manipulate mechanical and adhesive properties from the nanometre to the metre scale. We propose to address this challenge by - building an interdisciplinary research community with the aim of understanding and controlling cellular mechanics from the molecular to the organism scale. At the nanometric molecular level, we will develop cellular microenvironments enabled by - peptidomimetics of cell-cell and cell-matrix ligands, with defined mechanical and adhesive properties that we will dynamically control in time and space trough photo-activation. The properties under force of the molecular bonds involved will be - characterized using single-molecule atomic force microscopy and magnetic tweezers. At the cell-to-organ scale, we will combine controlled microenvironments and interfering strategies with the development of techniques to measure and control - mechanical forces and adhesion in cells and tissues, and to evaluate their biological response. At the organism scale, we will establish how cellular mechanics can be controlled, by targeting specific adhesive interactions, to impair or abrogate - breast tumour progression in a mouse model. At all stages and scales of the project, we will integrate experimental data with multi-scale computational modelling to establish the rules driving biological response to mechanics and adhesion. With this - approach, we aim to develop specific therapeutic approaches beyond the current paradigm in breast cancer treatment. Beyond breast cancer, the general principles targeted by our technology will have high applicability in oncology, regenerative - medicine and biomaterials. - - 2021-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.2."> - - - FETPROACT-01-2016 - FET Proactive: emerging themes and communities - - - RIA - Research and Innovation action - - - Spain - - - MECHANO-CONTROL - - - FETPROACT-2016 - - - 731957 - - - - - INTEGRATED CARBON OBSERVATION SYSTEM EUROPEAN RESEARCH INFRASTRUCTURE CONSORTIUM - UNIVERSITETET I BERGEN - UNIVERSITA DEGLI STUDI DELLA TUSCIA - UNIVERSITE DE VERSAILLES SAINT-QUENTIN-EN-YVELINES. - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - USTAV VYZKUMU GLOBALNI ZMENY AV CR VVI - RIJKSUNIVERSITEIT GRONINGEN - NATURAL ENVIRONMENT RESEARCH COUNCIL - HELSINGIN YLIOPISTO - LUNDS UNIVERSITET - Eidgenössische Technische Hochschule Zürich - UNIVERSITEIT ANTWERPEN - NATIONAL INSTITUTE OF RESEARCH AND DEVELOPMENT FOR OPTOELECTRONICS - ORSZAGOS METEOROLOGIAI SZOLGALAT - UNIVERSIDAD DE LAS PALMAS DE GRAN CANARIA - NATIONAL OBSERVATORY OF ATHENS - UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN - EESTI MAAULIKOOL - Instituto Superior de Agronomia - UNIVERSITY OF THE WITWATERSRAND JOHANNESBURG - UNIWERSYTET PRZYRODNICZY W POZNANIU* - DANMARKS TEKNISKE UNIVERSITET - HELMHOLTZ ZENTRUM FUR OZEANFORSCHUNG KIEL - UNIVERSITAET BREMEN - JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN - INSTITUT ROYAL D'AERONOMIE SPATIALEDE BELGIQUE - DEUTSCHER WETTERDIENST - LEIBNIZ-INSTITUT FUR OSTSEEFORSCHUNG WARNEMUNDE STIFTUNG - - - EUR 4 719 680 - - - Readiness of ICOS for Necessities of integrated Global Observations - - - EUR 4 719 680 - - - Finland - Norway - Italy - France - Germany - Czech Republic - Netherlands - United Kingdom - Finland - Sweden - Switzerland - Belgium - Romania - Hungary - Spain - Greece - Ireland - Estonia - Portugal - South Africa - Poland - Denmark - Germany - Germany - Germany - Belgium - Germany - Germany - - - Other - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - - The proposed project “Readiness of ICOS for Necessities of integrated Global Observations” (RINGO) aims to further development of ICOS RI and ICOS ERIC and foster its sustainability. The challenges are to further develop the - readiness of ICOS RI along five principal objectives: - - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-03-2016-2017 - Individual support to ESFRI and other world-class research infrastructures - - - CSA - Coordination and support action - - - Finland - - - RINGO - - - H2020-INFRADEV-2016-1 - - - 730944 - - - - - UNIVERSITA DEGLI STUDI DI PAVIA - ECOLE ROYALE MILITAIRE - KONINKLIJKE MILITAIRE SCHOOL - UNIVERSIDAD DE EXTREMADURA - - - EUR 270 000 - - - TOOLS FOR MAPPING HUMAN EXPOSURE TO RISKY ENVIRONMENTAL CONDITIONS BY MEANS OF GROUND AND EARTH OBSERVATION DATA - - - EUR 324 000 - - - Italy - Belgium - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The goal of the EOxposure project is to build tools to quantify the exposure of population and economic assets to multiple risks using novel information layers from current and future Earth Observation (EO) missions, as well - as the growing sensor web on the ground. - - 2021-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Italy - - - EOXPOSURE - - - H2020-MSCA-RISE-2016 - - - 734541 - - - - - GOETEBORGS UNIVERSITET - UNIVERSITY COLLEGE LONDON - UNIVERSITEIT VAN AMSTERDAM - INSTITUTO UNIVERSITARIO DE LISBOA - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - UNIVERSITEIT HASSELT - UNIVERSITEIT UTRECHT - ISTITUTO PER I BENI ARTISTICI CULTURALI E NATURALI DELLA REGIONE EMILIA ROMAGNA - - - EUR 3 867 561 - - - Critical Heritage Studies and the Future of Europe_Towards an integrated, interdisciplinary and transnational training model in cultural heritage research and management - - - EUR 3 867 561 - - - Sweden - United Kingdom - Netherlands - Portugal - Spain - Belgium - Netherlands - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - CHEurope focuses on developing a new integrated theoretical and methodological framework to enhance the academic and professional training and open future job opportunities in cultural heritage preservation, management and - promotion. Heritage has commonly been perceived through its contingent relationship to other areas, preventing it to be considered as a ‘legitimate’ scientific discipline. Moreover, research and practice in this field are still too often seen as - separate dimensions. Thus, there is an increasing need to address these diverging trends in the expanding heritage industry with a critical approach that situates cultural heritage in its social, economic and political frameworks, as well as in - professional practice. - - - 2020-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Sweden - - - CHEurope - - - H2020-MSCA-ITN-2016 - - - 722416 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 195 454,80 - - - Anti-EGFR Monoclonal Antibody Conjugated Thermoresponsive Liposome for Triple Negative Breast Cancer Thermo-Chemotherapy - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - In Europe, breast cancer is by far the most important cause of cancer death among women. In particular, triple negative breast cancer (TNBC) is an aggressive histological subtype with limited treatment options and associated - with poorer prognosis than other breast cancer subtypes. MULTIFUNSOME proposes the use of an anti-Epidermal Growth Factor Receptor (EGFR) monoclonal antibody-conjugated thermoresponsive liposome to deliver simultaneously an anticancer drug and - superparamagnetic iron oxide nanoparticles (SPIO) to TNBC cells for thermo-chemotherapy. We will investigate: 1) the effect of combining anti-EGFR targeting and magnetic hyperthermia (MH) on TNBC in such thermo-chemotherapy and 2) how - chemical-physical properties of the SPIOs and liposomes influence the therapeutic activity of the formulation. By conjugating anti-EGFR monoclonal antibody to a liposomal delivery system for targeting, drug and SPIO internalization into EGFR - overexpressing TNBC cells will be greatly enhanced. SPIO co-encapsulation in the drug nano-cargo will induce a thermal dose to the TNBC cells when an alternating magnetic field is applied. MH will make TNBC cells more sensitive to chemotherapy and - trigger the release of drugs intracellularly by enhancing the lipid membrane permeability. As a result, the effectiveness of chemotherapy could be synergistically enhanced by the concurrent application of MH and chemotherapy. The core size of SPIO - will serve as a design parameter that can be readily manipulated to maximize the heating efficient of the multicore SPIO so as to minimize the necessary iron oxide content and maximize the drug encapsulation efficiency. The fellowship program will - include a comprehensive training which will help the fellow to develop a unique multidisciplinary expertise. Furthermore, the project will generate important knowledge, impacts and collaborations in the European Research Area and could potentially - address the critical need for a more efficacious TNBC therapy. - - 2019-08-31, Grant Agreement terminated - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - MULTIFUNSOME - - - H2020-MSCA-IF-2015 - - - 700309 - - - - - WEIZMANN INSTITUTE OF SCIENCE - WEIZMANN INSTITUTE OF SCIENCE - - - EUR 150 000 - - - SFICAM: Ultrafast Fiber-Based Single-Photon Camera for Advanced Microscopy - - - EUR 150 000 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Light microscopy is critical to many fields, from biology and medicine to technology development and industry. One important breakthrough that enabled the development of super-resolution microscopy was the development of - enhanced cameras capable of recording low light-level images with single-photon sensitivity. However such gain in spatial resolution is compromised by low temporal resolution, since these cameras work at video rate or somewhat faster, while many - applications require to characterize dynamics which could be a million times faster. - - - 2019-02-28, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Israel - - - SFICAM - - - ERC-2017-PoC - - - 779971 - - - - - UNIVERSITE CATHOLIQUE DE LOUVAIN - - - EUR 160 800 - - - The top quark crucible: Standard Model and beyond the Standard Model physics in top quark precision studies - - - EUR 160 800 - - - Belgium - - - Higher or Secondary Education Establishments - - This proposal describes the exploration of properties of the top quark for the study of Standard Model physics and tests of physics beyond the Standard model. Research will be conducted starting from the data of 13 TeV run of - the Large Hadron Collider with particular focus on the determination of the top quark mass and other observables that might be sensitive to subtle new physics, which hides in standard searches for new physics carried out at the Large Hadron Collider - experiments, in particular searches that suffer from large systematic uncertainties in the sensitive regions of phase space. - - 2019-08-31, Grant Agreement terminated - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Belgium - - - TQCRCBL - - - H2020-MSCA-IF-2015 - - - 702768 - - - - - THE UNIVERSITY OF WARWICK - - - EUR 195 454,80 - - - Beyond the Secular: Narrativizing religious change in contemporary German novels - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The death of God and the disenchantment of the world are central to self-presentations of modernity. At the dawn of the third millennium, however, the worldwide growth of religious fundamentalisms as well as the pluralisation - and individualization (but not the disappearance) of faith in the West suggest the need for a more nuanced understanding of the relation between secularity, modernity and religion. This is not only a matter for empirical research in Social, Political - and Religious Studies. “Modernity,” “secularity” and “religion” are, in important ways, interpretive categories shaped by cultural narratives through which individuals and societies understand their world. The project “Beyond the Secular” studies a - defined corpus of such narratives: contemporary German-language novels which articulate non-secular and religious experiences and worldviews. Through an interdisciplinary methodology combining close reading and narratological analysis with contextual - readings in religious sociology, theology, and political philosophy, the project seeks to determine the potential of literature for the perception and narrativization of religious change in late modern societies. - - 2018-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - BeSec - - - H2020-MSCA-IF-2014 - - - 656000 - - - - - LUNDS UNIVERSITET - LUNDS UNIVERSITET - - - EUR 1 969 445 - - - Pancreatic islet dysfunction and type 2 diabetes – beyond the genome - - - EUR 1 969 445 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The prevalence of type 2 diabetes (T2D) is rapidly increasing worldwide and despite great efforts to prevent and cure the disease, the increase persist. There is an urgent need to develop innovative and effective prevention - and treatment strategies for T2D. - - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Sweden - - - PAINTBOX - - - ERC-2016-COG - - - 725840 - - - - - KOBENHAVNS UNIVERSITET - KOBENHAVNS UNIVERSITET - - - EUR 2 176 250 - - - The Ocular Glymphatic System - - - EUR 2 176 250 - - - Denmark - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The glymphatic system is a highly organized brain-wide mechanism by which fluid wastes are removed from the brain that was recently described by my team. The glymphatic system clears 65% of amyloid-beta from the normal adult - brain. A rapidly evolving literature has shown that the major neurodegenerative diseases of the eye, macular degeneration and glaucoma, may also result from the toxicity of uncleared protein wastes, including amyloid-beta. Yet the eye, like the - brain, has no traditional lymphatic vessels. In this application, I propose that two of the most significant causes of human visual loss, macular degeneration and glaucoma – previously thought of as both intractable and unrelated – are instead - mechanistically allied disorders that not only share a common causal pathway, but may both be therapeutically modified by targeting dysregulation of the glymphatic pathway. As such, this proposal seeks to link the biology of a fundamentally new - pathway for both metabolic substrate and waste transport in the adult brain, to diseases of the eye that have long been resistant to either understanding or treatment. - - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Denmark - - - GlymphEye - - - ERC-2016-ADG - - - 742112 - - - - - KAROLINSKA INSTITUTET - - - EUR 173 857,20 - - - Nano Traction - - - EUR 173 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - In this Marie Skłodowska-Curie Fellowship project entitled “Nano Traction” I will design a platform for the directed autonomous movement of nano- and microparticles. This will be achieved using a completely novel form of - traction based on the dynamic covalent attachment of the particles to a surface. Asymmetrically applied redox potentials will induce motion allowing the electrical control of nano- and microparticle motion and the creation of particles that - autonomously move and seek out cells that are producing reactive oxygen species a key indicator of disease. This Fellowship will be undertaken under the supervision of Prof. Molly Stevens in the Division of Biomaterials and Regenerative Medicine at - the Karolinska Institute (KI), which has the world-leading expertise in functional nanomaterial synthesis, biomaterials engineering, cell biology and tissue engineering crucial to the objectives of this proposal. This ground-breaking new method of - particle control at micro and nanometre length scales will have application in many areas including; precision actuation for nanorobotics and microfluidics and; the creation of cell seeking particles for biosensing and the targeted delivery of - nanoparticle agents. It will not only initiate new research areas at the cutting edge of nano- and biomaterials science, but will help me to establish my own independent research career following the proposed Fellowship. - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - Nano Traction - - - H2020-MSCA-IF-2016 - - - 747414 - - - - - KOBENHAVNS UNIVERSITET - - - EUR 200 194,80 - - - Investigating Changes in Antarctic Marine Ecosystems using Environmental DNA - - - EUR 200 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - The earth's climate is changing rapidly and nowhere more so than in polar regions. The Intergovernmental Panel on Climate Change has noted that polar marine ecosystems are especially vulnerable to climate change impacts, - through the synergistic effects of both thermal climate changes and ocean acidification. How such impacts will transpire biologically and the flow-on effects from this are quite unclear, and there is broad acknowledgment of this scientifically and in - terms of public policy. Polar ecosystems are extremely difficult to work in and gather field data from, so there is a strong need to appraise the efficacy of powerful new techniques for studying them. This project (ICEDNA) proposes to appraise and - apply the nascent technique of environmental DNA (eDNA) analysis to elucidate how polar marine ecosystems respond to environmental impacts. ICEDNA leverages on recent manipulative and ecological field experiments in Antarctic nearshore ecosystems. - These experiments focused on detection of fine scale human impacts from research stations and the biological impacts from ocean acidification. By marrying spatially and temporally nested eDNA data with traditional physical, chemical and biological - data collection techniques, ICEDNA will yield a thorough understanding of the uses and limits of eDNA for marine (and polar) biodiversity and ecological monitoring, which is at the forefront of marine ecological research. These data will also yield - unprecedented insight into (1) how polar marine communities respond to small scale human impacts and (2) how these communities respond to the large scale human impact of ocean acidification. ICEDNA combines the latest eDNA methods from Europe with - the applicants extensive applied ecology experience, to produce a dynamic multidisciplinary researcher. - - 2019-11-24, ongoing project - - - 2017-11-25 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - Denmark - - - ICEDNA - - - H2020-MSCA-IF-2016 - - - 749851 - - - - - STICHTING KATHOLIEKE UNIVERSITEIT - - - EUR 177 598,80 - - - Tuning Emergent Phases in 2D Materials - - - EUR 177 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - The goal of EMERGE is to create new types of two-dimensional materials of the highest quality, and exploit new types of quantum phenomena that emerge in the lower dimensional limit. By combining ultra-high purity fabrication - of 2D materials with a high level of control, with high precision spectroscopy, we aim at being able to tailor the phase of these materials with atomic precision. Since the discovery of graphene, there has been an ongoing search for new Dirac - materials which exhibit exotic electronic behavior in the two-dimensional limit, in which the spin and electronic degrees of freedom can be manipulated. Toward this end, the family of transition metal dichalcogenides (TMDCs) is extremely promising, - as this family of materials exhibits semiconducting behavior, novel spin transport, charge ordering, and superconductivity, when simply selecting the transition metal ion and the interface. However, the role of the environment and how this determines - the quantum phases of these materials is still not well understood, and moreover there are still many of these materials which have not been realized. The objective here will be to fabricate and tune TMDCs at the 2D limit, to realize new types of - TMDCs, in order to realize exotic phases of matter to unravel the role of the environment and material in creating and discovering new types of quantum phases of matter in these materials. Our goals will be accomplished by combining CVD fabrication - of TMDC single layers in ultra-high vacuum, with in-situ characterization of these films with cutting edge spin-polarized scanning tunneling microscopy at ultra-low temperature and high magnetic fields, and angular resolved photoemission in order to - fully understand the electronic properties of our materials. - - 2019-08-03, ongoing project - - - 2017-08-04 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - EMERGE - - - H2020-MSCA-IF-2016 - - - 751437 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 171 460,80 - - - Epigenetically Stable Cloned Plants: Increasing The Epigenetic and Phenotypic Diversity of Plants through Tissue-Specific Regeneration - - - EUR 171 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Most of phenotypic variation comes from variation in DNA sequence. However, a number of studies have clearly shown that phenotype variation and diversity can also be the result of epigenetic changes. The major goal of this - proposal is to develop a novel methodology for robust production of epigenetically stable plant variants, in order to increase epigenetic and phenotypic diversity. A key element in the project will be a recent breakthrough in the generation of clonal - individuals from different tissue types using inducible overexpression of the embryonic regulatory protein RKD4. Preliminary work shows that plants regenerated from roots inherit many aspects of root specific methylation and gene expression patterns, - even in the leaf tissue. Importantly, these features are stably transmitted across generations. For this project, I propose to: (1) evaluate physiological consequences of altered epigenomes in RKD4 regenerated plants; (2) compare (epi)genomic and - phenotypic variation between plants regenerated using hormones and RKD4 overexpression; (3) compare epigenomic and phenotypic consequences in regenerants of different Arabidopsis thaliana accessions and close A. thaliana relatives Arabidopsis lyrata - and Capsella rubella. The program, which will be carried out under supervision of Detlef Weigel, a world leader in plant genetics and genomics, will substantially contribute to increasing the toolkit for plant breeders to generate meaningful - phenotypic diversity. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - Epi-Somaclone - - - H2020-MSCA-IF-2016 - - - 751204 - - - - - THE UNIVERSITY OF MANCHESTER - THE UNIVERSITY OF MANCHESTER - - - EUR 147 963,75 - - - Hybrid Membranes Incorporating Metal-Organic Frameworks - - - EUR 147 963,75 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Research undertaken on ERC Advanced Grant 226593 (COORDSPACE) has delivered a new exciting range of metal organic frameworks (MOFs). These substances show ultra-high porosity and this makes them ideal for many high value - commercial applications, including gas separations. Of specific interest is NOTT-300, a unique, porous solid with exceptional, selective, CO2 and SO2 uptake properties and remarkable acetylene vs ethylene, ethylene vs ethane, and CO2 vs CH4 - separation abilities. We now target the incorporation of NOTT-300 into gas separation media to impart these systems with the extraordinary properties of NOTT-300 to fulfil an urgent unmet need within a range of industries. This project will develop - and deliver a market-ready mixed matrix membrane (MMM) incorporating NOTT-300 - - 2017-11-30, closed project - - - 2015-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2014 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - MemMOFs - - - ERC-2014-PoC - - - 665632 - - - - - LUNDS UNIVERSITET - LUNDS UNIVERSITET - - - EUR 1 875 000 - - - Novel Approach to Systematically Characterize Exercise- and Nutrient- responsive genes in Type 2 diabetes and cardiovascular disease - - - EUR 1 875 000 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Proposal summary - - 2022-01-31, ongoing project - - - 2017-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Sweden - - - NASCENT - - - ERC-2015-CoG - - - 681742 - - - - - STICHTING KATHOLIEKE UNIVERSITEIT - - - EUR 165 598,80 - - - Neural correlates of working memory control in aged bilinguals - - - EUR 165 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Identification of factors that slow down cognitive depletion in ageing is today one of the main objectives of the aged society. Within the concept of cognitive reserve (CR), bilingualism has evidenced to shape cognition by - enhancing the capacity of cognitive control (CgCnt). CgCnt and working memory (WM) capacities are strongly interrelated systems which are depleted by ageing. However, the exploration of how bilingualism shapes cognition in old populations is scarce - and recently subjected to debate. Under this framework, sensitive approaches (such as the exploration of the neural oscillatory activity) that enable objective investigation of the effects of bilingualism on cognitive ageing are necessary. Neural - oscillations represent the mechanisms responsible for cognition. Furthermore, they offer a direct measure of the cognitive architecture and of any reorganizational process accounting in the brain by factors as bilingualism. Nevertheless, the neural - code of WM control in old bilinguals has not been explored yet. The current project aims to investigate, with magnetoencephalography (MEG), the neural correlates of WM control in young and old adult bilingual individuals. Resulting data will open a - window into the role of bilingualism on the neural architecture of the working brain. - - 2017-12-31, closed project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - NeWMaBIL - - - H2020-MSCA-IF-2014 - - - 657255 - - - - - LUNDS UNIVERSITET - LUNDS UNIVERSITET - - - EUR 1 985 818 - - - The next-generation planet formation model - - - EUR 1 985 818 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The goal of this ERC Consolidator Grant proposal is to make significant contributions to our understanding of the formation of planetary systems and the chemical composition of planets. I will achieve this by developing a - planet formation model that integrates the most relevant physical processes and combines the newly discovered pebble accretion mechanism with gravitational interaction between a high number of growing embryos. Exploiting the results of the computer - simulations will allow me to address three major, outstanding research questions in the study of planets and their formation: - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Sweden - - - PLANETESYS - - - ERC-2016-COG - - - 724687 - - - - - LUNDS UNIVERSITET - LUNDS UNIVERSITET - - - EUR 1 999 412 - - - Learning to See in a Dynamic World - - - EUR 1 999 412 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The goal of SEED is to fundamentally advance the methodology of computer vision by exploiting a dynamic analysis perspective in order to acquire accurate, yet tractable models, that can automatically learn to sense our visual - world, localize still and animate objects (e.g. chairs, phones, computers, bicycles or cars, people and animals), actions and interactions, as well as qualitative geometrical and physical scene properties, by propagating and consolidating temporal - information, with minimal system training and supervision. SEED will extract descriptions that identify the precise boundaries and spatial layout of the different scene components, and the manner they move, interact, and change over time. For this - purpose, SEED will develop novel high-order compositional methodologies for the semantic segmentation of video data acquired by observers of dynamic scenes, by adaptively integrating figure-ground reasoning based on bottom-up and top-down - information, and by using weakly supervised machine learning techniques that support continuous learning towards an open-ended number of visual categories. The system will be able not only to recover detailed models of dynamic scenes, but also - forecast future actions and interactions in those scenes, over long time horizons, by contextual reasoning and inverse reinforcement learning. Two demonstrators are envisaged, the first corresponding to scene understanding and forecasting in indoor - office spaces, and the second for urban outdoor environments. The methodology emerging from this research has the potential to impact fields as diverse as automatic personal assistance for people, video editing and indexing, robotics, environmental - awareness, augmented reality, human-computer interaction, or manufacturing. - - 2020-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Sweden - - - SEED - - - ERC-2014-CoG - - - 648379 - - - - - OBSERVATOIRE DE LA COTE D'AZUR (OCA) - OBSERVATOIRE DE LA COTE D'AZUR (OCA) - - - EUR 1 717 811 - - - Ultimate Angular Resolution Astrophysics with kernel-phase and full-aperture interferometry - - - EUR 1 717 811 - - - France - France - - - Research Organisations - Research Organisations - - Astronomy requires large telescopes to improve the sensitivity and the angular resolution of its observations. Of these qualities, angular resolution is the most difficult to maintain in the optical and near-infrared, since - the atmosphere reduces it to that of a 10 cm aperture, regardless of the telescope size. On the one-hand, Adaptive Optics (AO) actively compensates for this effect but the improvement is often partial only. On the other hand, interferometric - techniques (most notably sparse aperture masking interferometry) passively allow the extraction of self-calibrating observables, that boost the angular resolution, but severely affect the sensitivity of observations. A framework newly established by - the PI of the proposal however now makes it possible to extract generalized self-calibrating observables called kernel-phases from conventional AO-corrected images. The work outlined in this proposal will make it possible to scientifically exploit - the high angular resolution imaging capability of this technique, to improve its robustness and to expand its capabilities. The framework offers a very general purpose high angular resolution imaging tool for astronomers as well as wavefront control - experts. This proposal is organized in five work-packages of increasing challenge that include: the reinterpretation of existing archival data with a super-resolution capability, the expansion of its robustness to open up new more challenging - use-cases, a special focus on the development of a very high-dynamic range mode, the adaptation of interferometric image reconstruction techniques, and the development of new advanced AO concepts. The consequences of this project will have a major - impact on the design and scientific exploitation of future high angular resolution instrumentation on the existing generation of 8-10 meter class telescopes as well as on the upcoming generation of 30-40 meter giants, championned by Europe and its - E-ELT. - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - France - - - KERNEL - - - ERC-2015-CoG - - - 683029 - - - - - AARHUS UNIVERSITET - - - EUR 212 194,80 - - - The influence of Earth-surface processes on solid-Earth, ice-sheet, and sea-level interactions for Scandinavian Ice-Sheet collapse - - - EUR 212 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - One of the grand challenges for society in the future will be to cope with the consequences of a changing climate and resulting changes in global sea level. Yet, predictions of past and future scenarios are associated with - significant uncertainties, as we do not currently understand all processes that influence ice-sheet variability and thereby global ice volume. One key shortcoming relates to Earth-surface processes. Fjord formation by selective glacial erosion has - the potential to elevate surrounding regions significantly by erosional unloading (~1 km in Greenland). However, the consequences for ice-sheet dynamics and global sea level have never been explored. My approach is to combine state-of-the-art - numerical modelling efforts from the two disciplines of sea-level research and glacial geomorphology with empirical data analysis, in order to investigate the influence of such processes on the solid Earth, ice sheets, and sea level. I will apply - this novel modelling scheme to study the former Scandinavian Ice Sheet (SIS), where remarkable empirical constraints exist on glacial isostatic rebound, past ice sheet extent, and deposited sediment volumes. By investigating a former ice sheet, I - will improve our understanding of processes that are highly relevant for the future evolution of existing ice sheets. This will improve the scientific basis for decision makers to shape well-founded policies for optimal adaptation to future sea-level - changes. While acquiring new expertise in glacial geology and sedimentology, I will i) constrain solid-Earth deformation and global sea-level changes due to Quaternary erosion and deposition in the Scandinavian region, ii) assess the influence of - long-term glacial erosion for SIS dynamics, ice volume, and sea-level contributions, and iii) gain significant insight into important interactions between surface processes, solid-Earth deformation, ice-sheet variability and sea-level change, and - improve our understanding of SIS collapse. - - 2020-07-31, Grant Agreement signed - - - 2018-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - EROSIVE - - - H2020-MSCA-IF-2016 - - - 745669 - - - - - ITA-SUOMEN YLIOPISTO - EBERHARD KARLS UNIVERSITAET TUEBINGEN - THE QUEEN'S UNIVERSITY OF BELFAST - UNIVERSITE DE STRASBOURG - TECHNISCHE UNIVERSITEIT EINDHOVEN - UNIVERSITA DEGLI STUDI DI PADOVA - UNIVERSITEIT UTRECHT - OZ BIOSCIENCES SAS - SIMCYP LIMITED - - - EUR 3 933 729,36 - - - Educational Network in Ocular Drug Delivery and Therapeutics - - - EUR 3 933 729,36 - - - Finland - Germany - United Kingdom - France - Netherlands - Italy - Netherlands - France - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Ocular drug development has transformed from niche area to a major field in drug development in which many companies, including European big pharma has entered recently. Ocular drug development is a unique field in terms of - drug targets and end-points of activity, local drug administration routes, tissue barriers and pharmacokinetics, drug delivery and formulation challenges and local toxicity issues. These issues are slowing down the development of drugs for the unmet - needs in ophthalmology. The main objective of the proposal is to educate experts of preclinical ocular R&D to facilitate the success of European pharmaceutical industry and research community. This objective will be reached by joining forces of - the leading European academic and industrial researchers in ophthalmology, materials science and nanomedicine, drug delivery and targeting, and systems pharmacology. We shall educate 15 Early Stage Researchers in a network where they will receive - tailored, multi-disciplinary and inter-sectoral education in preclinical ocular drug development. The thesis projects are directed to the drug treatment of retinal diseases, the major challenge in the field. The proposal combines new drug candidates - from the experts of ophthalmology, innovative drug delivery technologies from pharmaceutical scientists and companies, and modern in vitro, in silico and in vivo methods from various partners. The thesis projects include secondments in academic and - industrial partner laboratories and course programme that encompasses the relevant fields in ocular drug development. Therefore, this proposal presents unique combination of innovation and education in the field with obvious need for such education. - The ESRs and other outcomes of this project will greatly benefit the future competitiveness of European science and industry in this field of expanding importance. - - 2020-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Finland - - - OcuTher - - - H2020-MSCA-ITN-2016 - - - 722717 - - - - - LUNDS UNIVERSITET - LUNDS UNIVERSITET - - - EUR 2 621 251 - - - Deciphering cell heterogeneity in tumors using arrays of nanowires to controllably poke single cells in longitudinal studies - - - EUR 2 621 251 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Cancer is responsible for 20% of all deaths in Europe. Current cancer research is based on cell ensemble measurements or on snapshot studies of individual cells. However, cancer is a systemic disease, involving many cells that - interact and evolve over time in a complex manner, which cell ensemble studies and snapshot studies cannot grasp. It is therefore crucial to investigate cancer at the single cell level and in longitudinal studies (over time). Despite the recent - developments in micro- and nanotechnologies, combined with live cell imaging, today, there is no method available that meets the crucial need for global monitoring of individual cell responses to stimuli/perturbation in real-time. - - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Sweden - - - NanoPokers - - - ERC-2015-CoG - - - 682206 - - - - - UNIVERSITY OF BATH - UNIVERSITY OF BRISTOL - UNIVERSITAT ZURICH - MICROSEMI SEMICONDUCTOR LIMITED - MEDTRONIC BAKKEN RESEARCH CENTER B.V. - MEDIZINISCHE UNIVERSITAET WIEN - UNIVERSITAIR MEDISCH CENTRUM UTRECHT - FAKULTNI NEMOCNICE U SV. ANNY V BRNE - - - EUR 4 944 347,50 - - - Adaptive Bio-electronics for Chronic Cardiorespiratory Disease - - - EUR 4 944 347,50 - - - United Kingdom - United Kingdom - Switzerland - United Kingdom - Netherlands - Austria - Netherlands - Czech Republic - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This consortium will pioneer disruptive technology for bio-electronic medicine to provide much needed therapies for cardiorespiratory and functional neurological disease. The technology implements small neural networks known - as central pattern generators (CPG) to deliver fit-and-forget bio-electronic implants that respond to physiological feedback in real time, are safer, simpler, non-invasive, and have autonomy exceeding the patient lifespan. Multichannel neurons will - be made to compete on analogue chips to obtain flexible motor sequences underpinned by a wide parameter space. By building large scale nonlinear optimization tools and using them to assimilate electrophysiological data, we will develop a method for - automatically finding the network parameters that accurately reproduce biological motor sequences and their adaptation to multiple physiological inputs. In this way, we will have resolved the issue of programming analogue CPGs which has long been the - obstacle to using neural chips in medicine. An adaptive pacemaker will be constructed, tested, validated and trialled on animal models of atrio-ventricular block and left bundle branch block to demonstrate the benefits of heart rate adaptation, - beat-to-beat cardiac resynchronization and respiratory sinus arrhythmia. By providing novel therapy for arrhythmias, heart failure and their comorbidities such as sleep apnoea and hypertension, CResPace will extend patients’ life and increase quality - of life. - - 2021-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.2."> - - - FETPROACT-01-2016 - FET Proactive: emerging themes and communities - - - RIA - Research and Innovation action - - - United Kingdom - - - CResPace - - - FETPROACT-2016 - - - 732170 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - ALBERT-LUDWIGS-UNIVERSITAET FREIBURG - KLINIKUM DER UNIVERSITAET ZU KOELN - ACADEMISCH ZIEKENHUIS LEIDEN - MEDIZINISCHE UNIVERSITAET WIEN - TECHNISCHE UNIVERSITAET WIEN - FUNDACION PARA LA INVESTIGACION MEDICA APLICADA FIMA - UNIVERSITY OF BRISTOL - UNIVERSITAETSKLINIKUM WUERZBURG - KLINIKUM DER BAYERISCHEN JULIUS-MAXIMILIANS-UNIVERSITAT - STRATEC CONSUMABLES GMBH - - - EUR 2 539 859,76 - - - European Network on Anti-Cancer Immuno-Therapy Improvement by modification of CAR and TCR Interactions and Nanoscale Geometry - - - EUR 2 539 859,76 - - - Spain - Germany - Germany - Netherlands - Austria - Austria - Spain - United Kingdom - Germany - Austria - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The EN-ACTI2NG program (European Network on Anti-Cancer Immuno-Therapy Improvement by modification of CAR and TCR Interactions and Nanoscale Geometry) emanates from the recent clinical evidence that T cells expressing - engineered tumor-specific immune receptors can eradicate certain tumors that do not respond to conventional treatment. To obtain T cells with reactivity to a wider array of tumors and to improve efficiency and on- and off-target toxicity are current - challenges Therefore the EN-ACTI2NG program aims 1) to train PhD students with expertise in development of new and improved T cell-mediated cancer immuno-therapies; 2) to endow the PhD students with the ability to establish efficient communication - between the academic and industrial research environments and between scientists and the general public; 3) to improve T cell mediated anti-cancer immuno-therapy by the identification and development of new cancer-specific immune receptors and - enhancing their function by identifying and modifying their molecular mechanism of action. To reach these objectives we have designed individual research projects ranging from biophysical analysis of immune receptors, via molecular modification of - their structure and testing their tumor killing capacity in cell-based and pre-clinical assays to product development. Secondments will assure that each PhD student will be exposed to these complementary approaches and that there will be synergic - feedback between the projects, producing innovative results that could otherwise not be achieved. Extensive training in research-specific skills, career development and a continuous training in communication skills will allow the PhD students to - become facilitators of the process of transformation of scientific innovation into products with social and economic value. As such, the EN-ACTI2NG program should contribute to overcoming the more general challenge of converting the European - Community into an innovation-driven society. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Spain - - - EN_ACTI2NG - - - H2020-MSCA-ITN-2016 - - - 721358 - - - - - UNIVERSITY OF BRISTOL - BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY - - - EUR 251 857,80 - - - The Basal Roughness of Ice Sheets from Radio-Echo Sounding - - - EUR 251 857,80 - - - United Kingdom - United States - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The subglacial environment beneath the Greenland and Antarctic ice sheets is one of the physically least well characterised environments on Earth. Ice sheet model simulations demonstrate high sensitivity to their basal sliding - parameterisation which is governed by basal roughness, the thermal state of the bed, and lithology (presence or absence or deformable sediments). Compiling observations of the current state of the glacier bed is therefore crucial for the accuracy of - ice sheet modelling and future predictions of sea level change. Radio-echo sounding (RES) is the only existing geophysical technique that has sufficient data coverage to enable ice-sheet-wide information to be obtained from the bed. In general, - however, quantitative analysis of radar sounding data, and integration with electromagnetic and geostatistical approaches, lags significantly behind the data availability. - - 2020-08-20, ongoing project - - - 2017-08-21 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - BRISRES - - - H2020-MSCA-IF-2016 - - - 747336 - - - - - IE UNIVERSIDAD - - - EUR 158 121,60 - - - Between Social Values and Profitable Performance: The Case of B-Corporations - - - EUR 158 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - How entrepreneurs could profit from social responsible investments? This issue implies a balance between entrepreneurs’ investments in profitable business models and their engagement in non-profit social actions. To address - this question, the project studies the B-Corporations as a new legal business form of corporations (private and public) pursuing benefits for society and shareholders. A non-profit certifying organization, B-Lab, analyses the impact of these - companies on society, with particular attention to their ability to provide to ‘communities’ beneficial products or services. Although first established in US, now they are present in 34 countries across 121 industries. Employing this legal form of - social companies, the proposal exploits the notion of community-focused strategies (CFS) to refer to the actions that entrepreneurs should pursue to establish links with communities to fulfill reciprocal social values. If people join communities to - satisfy their identity needs, entrepreneurs might seek to align their ventures’ strategy to them to improve entrepreneurial performance. Building on social identity theory, entrepreneurial and strategy research, this project adopt mainly a - demand-oriented approach. First, it tries to explain differences in new ventures’ performance investigating how B-Corps interact with their communities and through them access customers’ information and gaining loyalty. Second, it explores and - profiles the B-Corps as new examples of social entrepreneurial ventures. Finally, it studies entrepreneurs’ strategies to develop long-term interactions with the communities. The statistical evidence is drawn from secondary data, surveys to - entrepreneurs, and lab experiments. Implications on ventures’ success rate, growth and drawbacks of the interplay between social entrepreneurship and CFS are discussed. - - 2018-05-31, ongoing project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - BCorp - - - H2020-MSCA-IF-2014 - - - 655676 - - - - - EUROPEAN MOLECULAR BIOLOGY LABORATORY - UNIVERSITAIR MEDISCH CENTRUM UTRECHT - FUNDACIO INSTITUT DE CIENCIES FOTONIQUES - FUNDACIO CENTRE DE REGULACIO GENOMICA - UNIVERSITY OF DUNDEE - BIOBANKS AND BIOMOLECULAR RESOURCES RESEARCH INFRASTRUCTURE CONSORTIUM (BBMRI-ERIC) - IDRYMA IATROVIOLOGIKON EREUNON AKADEMIAS ATHINON - ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM - EATRIS ERIC - ECRIN EUROPEAN CLINICAL RESEARCH INFRASTRUCTURE NETWORK - THE UNIVERSITY OF LIVERPOOL - ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI - HEINRICH-HEINE-UNIVERSITAET DUESSELDORF - INFRAFRONTIER GMBH - HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH - INSTRUCT ACADEMIC SERVICES LIMITED - CONSORZIO INTERUNIVERSITARIO RISONANZE MAGNETICHE DI METALLO PROTEINE - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - STAZIONE ZOOLOGICA ANTON DOHRN - THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS - FORSCHUNGSVERBUND BERLIN EV - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN - THE UNIVERSITY OF MANCHESTER - STICHTING VU - DEUTSCHES KREBSFORSCHUNGSZENTRUM - LEIBNIZ-INSTITUT DSMZ-DEUTSCHE SAMMLUNG VON MIKROORGANISMEN UND ZELLKULTUREN GMBH* - JACOBS UNIVERSITY BREMEN GGMBH - KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW - CSC-TIETEEN TIETOTEKNIIKAN KESKUS OY - CAB INTERNATIONAL - MEDIZINISCHE UNIVERSITAET WIEN - ACADEMISCH ZIEKENHUIS GRONINGEN - UNIVERSITA DEGLI STUDI DI TORINO - - - EUR 14 837 800 - - - Coordinated Research Infrastructures Building Enduring Life-science services - - - EUR 14 837 800 - - - Germany - Netherlands - Spain - Spain - United Kingdom - Austria - Greece - Netherlands - Netherlands - France - United Kingdom - Italy - Germany - Germany - Germany - United Kingdom - Italy - Spain - France - Italy - United Kingdom - Germany - United Kingdom - Germany - United Kingdom - Netherlands - Germany - Germany - Germany - Netherlands - Finland - United Kingdom - Austria - Netherlands - Italy - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Other - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Other - Research Organisations - Other - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Other - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The social and economic challenges of ageing populations and chronic disease can only be met by translation of biomedical discoveries to new, innovative and cost effective treatments. The ESFRI Biological and Medical Research - Infrastructures (BMS RI) underpin every step in this process; effectively joining scientific capabilities and shared services will transform the understanding of biological mechanisms and accelerate its translation into medical care. - - 2019-08-31, ongoing project | - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-4-2014-2015 - Implementation and operation of cross-cutting services and solutions for clusters of ESFRI and other relevant research infrastructure initiatives - - - RIA - Research and Innovation action - - - Germany - - - CORBEL - - - H2020-INFRADEV-1-2014-1 - - - 654248 - - - - - HAUS DER WISSENSCHAFT BRAUNSCHWEIG GMBH - TECHNISCHE UNIVERSITAET BRAUNSCHWEIG - - - EUR 189 000 - - - Crossing Borders - In jedem steckt ein Forscher / European Researchers Night 2014 + 2015 - - - EUR 189 000 - - - Germany - Germany - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - Crossing Borders, pushing the limits of knowledge, inventing new methods, technologies, materials to improve our life. That´s what research is all about. What is needed for this is simple: a clever mind and curiosity. With the - slogan Crossing Borders –there is a researcher in all of us we want to show how diverse research careers and findings can be and how they impact the everyday life. Furthermore, during the European Researchers´ Night we want to advertise research as a - career especially to young people. This is why we are bringing researchers into town - research is right at home in Braunschweig. Our region is one of the most research intensive regions in Europe, boasting the highest density of scientists. To make - this visible we are embarking in a bet: we want to assemble at least 1,000 researchers at a so-called Researcher-Flashmob. We expect around 10,000 visitors who are invited to be part of the bet before the event and who can be part of a whole range of - small events on the night to get up-and-close with the researchers. Events include playing games together, an elevator pitch, hands-on-experiments or a Science Slam. This way we are encouraging people to enjoy research and show how research makes - life easier. At the same time we dispel the myth surrounding researchers. An extensive awareness campaign before the event will help spreading the message even beyond the night itself. After the campaign we expect at least 85,000 people to know about - the European Researchers´ Night (ERN) and its objectives. - - - 2015-10-31, closed project | - - - 2014-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.5."> - - - MSCA-NIGHT-2014 - European Researchers' Night (NIGHT) - - - CSA - Coordination and support action - - - Germany - - - BS_Night_140926_150925 - - - H2020-MSCA-NIGHT-2014 - - - 633320 - - - - - JACOBS UNIVERSITY BREMEN GGMBH - RASDAMAN GMBH - PLYMOUTH MARINE LABORATORY - EUROPEAN CENTRE FOR MEDIUM-RANGE WEATHER FORECASTS - METEOROLOGICAL AND ENVIRONMENTAL EARTH OBSERVATION SRL - COMMUNICATION & INFORMATION TECHNOLOGIES EXPERTS ANONYMOS ETAIREIA SYMVOULEFTIKON KAI ANAPTYXIAKON YPIRESION - THE AUSTRALIAN NATIONAL UNIVERSITY - - - EUR 2 839 743 - - - Agile Analytics on Big Data Cubes - - - EUR 2 839 743,75 - - - Germany - Germany - United Kingdom - United Kingdom - Italy - Greece - Australia - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - EarthServer-2 makes Agile Analytics on Big Earth Data Cubes of sensor, image, simulation, and statistics data a commodity for non-experts and experts alike through - - 2018-04-30, ongoing project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.3."> - - - EINFRA-1-2014 - Managing, preserving and computing with big research data - - - RIA - Research and Innovation action - - - Germany - - - EarthServer-2 - - - H2020-EINFRA-2014-2 - - - 654367 - - - - - FUNDACIÓ MARKETS, ORGANIZATIONS AND VOTES IN ECONOMICS - - - EUR 158 121,60 - - - Peer effects and endogenous network formation - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - The aim of this project is to develop a theoretical and empirical framework to simultaneously study network formation and peer effects in education. The problem is important from a methodological perspective, as there do not - exist general purpose estimatable models of social dynamics in Economics which treat the network formation process as endogenous and simultaneously contemplate network effects on behaviour and its feedback on the network formation process. The - possibility of understanding the formation of social networks in terms of the characteristics of the agents forming links is severely limited in most applications by the presence of peer effects that alter these characteristics. Conversely one of the - main difficulties in measuring peer effects in any context is that peer groups are endogenous. This project will have two main components (1) a theoretical component and (2) an empirical/experimental component. The theoretical component aims to - construct and study in detail the properties of some models of peer effects treating network formation endogenously. In the empirical/experimental component I will estimate and test the models by (a) Relying on two datasets, one of which already - exists and one of which is under construction, and which I am currently using on two related projects and (b) Building a detailed longitudinal dataset including information on social network structure and various kinds of behaviours and attitudes - using surveys and economic experiments . - - 2017-05-31, closed project | - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - PEERS - - - H2020-MSCA-IF-2014 - - - 657332 - - - - - TECHNISCHE UNIVERSITAET BRAUNSCHWEIG - - - EUR 159 460,80 - - - Identification of cellular identities and characterization of the STAT3 signalling pathway in Purkinje cell layer regeneration - - - EUR 159 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - There are many degenerative diseases affecting the cerebellum (as certain cerebellar ataxia) with severe locomotor symptoms, in which the Purkinje cells (PCs), the sole-output cerebellar neurons, suffer from degeneration. The - adult regenerative capacity of neurons in mammals is extremely low. However, the zebrafish is a model organism that exhibits extensive adult neurogenesis and regeneration, and is therefore most likely to elucidate key cerebellar regenerative - mechanisms that are currently unknown. The proposed project will focus on the study of PC regeneration using an inducible cell type specific ablation technique, in which the recovery of PCs cannot involve the plasticity of remaining cells, making - this tool superior to existing protocols which rely on mechanical injuries. In such PC-ablated zebrafish the time course of PC layer recovery will be analyzed by behavioral tests, which will also reveal specific functions of the zebrafish cerebellum. - Cellular processes of regeneration will be revealed by the analysis of double transgenic zebrafish strains addressing: the cellular sources of regenerating PC progenitors, their spatial distribution, potential migratory routes of de novo - differentiating PCs, and cellular interactions accompanying a proper restoration of a functional PC layer. We also expect to obtain first insights into potential molecular processes involved in the degeneration-regeneration processes of PCs, - considering Stat3- signaling (with important roles in tissue restoration) as a promising candidate to promote PC regeneration by employing inhibitor studies, and to derive functional consequences for the organism. These results are fundamental to - understanding and eventually treating diseases affecting the cerebellum. Therefore, these studies about PCs regeneration in zebrafish will reach beyond basic research by revealing molecular and cellular potentials and constraints for neuronal - regeneration therapeutic approaches in the vertebrate brain. - - 2018-06-30, ongoing project - - - 2016-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Germany - - - PURKINJEREG - - - H2020-MSCA-IF-2015 - - - 703961 - - - - - JACOBS UNIVERSITY BREMEN GGMBH - TECHNISCHE UNIVERSITAET MUENCHEN - - - EUR 159 795,60 - - - Towards Intelligent Cognitive AUVs - - - EUR 159 795,60 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In recent years, long-term autonomy and persistent autonomy have ecome key areas of interest for marine robotics researchers. Ocean observatories require autonomous robot deployments over months or years. Deep-water oilfield - inspection and intervention with autonomous vehicles is now a commercial reality, but fielded robots rely heavily on accurate a priori models of the subsea assets. Robustness to errors in autonomous contact tasks requires detection of execution - errors. - - 2019-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Germany - - - TIC-AUV - - - H2020-MSCA-IF-2015 - - - 709136 - - - - - JACOBS UNIVERSITY BREMEN GGMBH - JACOBS UNIVERSITY BREMEN GGMBH - - - EUR 2 312 481 - - - Holomorphic Dynamics connecting Geometry, Root-Finding, Algebra, and the Mandelbrot set - - - EUR 2 312 481 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Dynamical systems play an important role all over science, from celestial mechanics, evolution biology and economics to mathematics. Specifically holomorphic dynamics has been credited as “straddling the traditional borders - between pure and applied mathematics”. Activities of numerous top-level mathematicians, including Fields medalists and Abel laureates, demonstrate the attractivity of holomorphic dynamics as an active and challenging research field. - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - HOLOGRAM - - - ERC-2015-AdG - - - 695621 - - - - - GENOME RESEARCH LIMITED - - - EUR 183 454,80 - - - Unravelling host intestine-parasite interactions that define immune responses to whipworms - - - EUR 183 454,80 - - - United Kingdom - - - Research Organisations - - Whipworms (Trichuris trichuira) are soil-transmitted helminths that infect about 700 million people in the tropics and sub-tropics and cause the human disease, trichuriasis. Whipworms live preferentially in the cecum of their - hosts where they tunnel through epithelial cells and cause inflammation potentially resulting in colitis. Despite extensive research, the role of whipworm interactions with epithelial and immune cells in triggering parasite expulsion remains unclear, - hindering the development of anti-parasite therapies. The ultimate goal of my research proposal is to investigate and understand this interaction in detail. To achieve this, I will use T. muris, a mouse model of T. trichuira infection in humans. This - research proposal has three key aims. First, to identify new parasite and host genes that could interplay and modulate immunological outcomes. Second, to characterize the role of host genes in whipworm infection and immunity. Here, novel and known - candidate mutations conferring susceptibility to colitis identified through the Wellcome Trust Sanger Institute - Mouse Genetics Project will be targeted. Thus, I will challenge mutant mouse lines with T. muris and evaluate the influence of these - mutations on anti-parasite immunity and expulsion. Finally, upon identification of key genes regulating the immune response to whipworms, I will explore the mechanism of action of selected genes and their effect on the parasite. For this, I will take - advantage of the vast range of ‘omic’ technologies and facilities available at the WTSI. This project will generate novel fundamental data on host-whipworms interactions and also support future efforts to control these parasites by the identification - of potential new therapeutic targets. Moreover, resulting knowledge of the parasiteimmunological interplay could be exploited to understand other intestinal inflammatory diseases such as ulcerative colitis that have many similarities with - trichuriasis. - - 2017-09-30, closed project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - GUTWORM - - - H2020-MSCA-IF-2014 - - - 656347 - - - - - UNIVERSITATEA POLITEHNICA DIN BUCURESTI - - - EUR 137 422,80 - - - LV DC microgrids for evolved energy communities - - - EUR 137 422,80 - - - Romania - - - Higher or Secondary Education Establishments - - Microgrids are an important concept in the emerging power industry field. They are widely recognized as an innovative eco-system when it comes to a flexible and reliable option for the integration of distributed energy - renewable resources (DER). The research on direct current (DC) power distribution systems is taking ground especially for applications where the end-use loads are natively DC (e.g. data centers, offices, residential). Efficiency, reliability, lower - capital cost, simpler control strategies, higher power quality are the most cited advantages compared with AC microgrids. The primary technical research objective of this project is the design and analysis of novel methods for management and control - of multiple building scale DC microgrids operating on a defined territory. Specifically the major technical objectives are: (a)To enhance the state of the art in the DC microgrid field with a holistic design, modelling, control framework for clusters - of LV building level DC microgrids (the emerging community prosumers of tomorrow;) (b) To develop and validate models for typical elements of DC microgrids. The models will follow an innovative and yet unexplored approach based on hybrid dynamic - system analysis; (c) To develop and test models for optimal operation of clusters of DC microgrids under uncertainty. The optimization models will look for different objectives to be optimized while taking into account the technical and economic - constraints of the systems operating in either stand-alone or interconnected mode; (d) To develop and validate distributed control schemes for ad-hoc clusters of DC microgrids. Career development objectives are: (a) To enhance the research skills of - the Fellow with complementary knowledge in power quality, modeling and control specific for DC grids, (b) To facilitate the transfer of knowledge to the society, scientific community and industry and to explore the commercial potential of the - research outcomes. - - 2018-06-30, ongoing project - - - 2016-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Romania - - - DCNextEve - - - H2020-MSCA-IF-2015 - - - 708844 - - - - - TECHNISCHE UNIVERSITAET BRAUNSCHWEIG - TECHNISCHE UNIVERSITAET BRAUNSCHWEIG - - - EUR 1 994 250 - - - Gain by Strain: Precise Cuts of Cyclopropanes as Key to Molecular Complexity - - - EUR 1 994 250 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - A central discipline of chemistry is the design und creation of molecules with defined structural and chemical properties. Stretching synthetic horizons is a never-ending endeavor to inspirit the chemist’ s creativity in - preparing compounds and materials yet to be discovered. Relying on their high strain energy cyclopropanes, as carriers of the most fundamental ring geometry, offer a unique reactivity which allows for a multitude of transformations being grouped in - ring-opening reactions, cycloadditions and rearrangements. Major advantage of all these processes is the cyclopropane-derived intrinsic atom-economy. - - 2020-06-30, ongoing project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - GAINBYSTRAIN - - - ERC-2014-CoG - - - 648711 - - - - - TECHNISCHE UNIVERSITAET GRAZ - UNIVERSITAET GRAZ - UNIVERSIDADE DO PORTO - TECHNISCHE UNIVERSITAT HAMBURG-HARBURG - RUHR-UNIVERSITAET BOCHUM - WAGENINGEN UNIVERSITY - UNIVERSITE D'AIX MARSEILLE - - - EUR 3 029 223,96 - - - Light-driven sustainable biocatalysis training network - - - EUR 3 029 223,96 - - - Austria - Austria - Portugal - Germany - Germany - Netherlands - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Pharmaceutical and chemical products present in everyday life are currently obtained from waste- and energy-intensive processes. Alternative routes that overcome this waste challenge should offer a cleaner and long-lasting - solution. PhotoBioCat aims at developing efficient and sustainable light-driven enzyme-catalyzed chemical processes to a commercial industrial level. The PhotoBioCat EJD will train 12 ESRs in cutting edge research projects on (i) the development of - chemical and biological catalytic systems for the synthetic use of visible light for the production of pharmaceuticals, bulk-, fine- and specialty chemicals, (ii) up-scaling and optimization of commercially relevant processes together with industry, - (iii) defining a road-map for the industrial implementation of photobiocatalysis. The double degree program allows in-depth training in two complementary disciplines, further strengthened by a transferable skills training with strong industry - participation. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-EJD - European Joint Doctorates - - - Austria - - - PhotoBioCat - - - H2020-MSCA-ITN-2017 - - - 764920 - - - - - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - - - EUR 175 419,60 - - - Association of Uranium with Organic Matter- and Iron-bearing Colloids in Wetland Environments - - - EUR 175 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - In the context of decreasing water standards for uranium (U) concentrations in drinking water, the use of natural or constructed wetlands is often proposed for cost-effective small-scale water treatment. The underlying - mechanism is immobilization of the dissolved form of uranium, U(VI), through its reduction to a less mobile form, U(IV). However, the long-term stability of U(IV) species formed is not well understood. Indeed, a significant amount of U is found - labile, even in its reduced form, and contaminates the hydrologic network in several sites. Previous studies suggest that the colloidal phase is responsible for the dispersion of U(IV) in the watershed. In addition, it has been hypothesized that the - propensity of the colloidal phase to bind and mobilize U(IV) depends on the association of Fe with colloidal natural organic matter (NOM), and on the colloids conformation. However, these hypotheses need to be investigated and information is lacking - on the processes leading to the formation of the pressented vector of U(IV) dissemination, i.e. Fe-NOM colloids. Understanding these processes is crucial for predicting the efficiency of wetlands as traps of U water contamination. We propose to (i) - further characterize wetland colloids, in a broader panel of wetlands, and use correlation analysis to pinpoint factors controlling the NOM shape and its ability for Fe- and U-binding; (ii) test in batch experiments the effect of Fe sources on NOM - properties in solution; and (iii) test the reactivity of Fe-NOM colloids with U(IV) and identify the U(IV) binding mechanisms at molecular levels. The original approach proposed will help decision making for uses of wetland filters, and also generate - fundamental knowledge about NOM reactivity. The project involves the state-of-the-art expertise of the host institute (EPFL) about U geochemistry in wetlands, and the complementary expertise of Geneva University about characterization of colloidal - organic matter. - - 2018-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - UMIC - - - H2020-MSCA-IF-2015 - - - 701542 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN - KAROLINSKA INSTITUTET - STOCKHOLMS LANS LANDSTING - UNIVERSITEIT GENT - UNIVERSITA DEGLI STUDI DI PADOVA - THE UNIVERSITY OF SHEFFIELD - SP PROCESS DEVELOPMENT AB - UNIVERSITAET BERN - TURUN YLIOPISTO - MEDIMMUNE LIMITED - ASTRAZENECA AB - - - EUR 3 971 347,92 - - - Molecular Tools for Nucleic Acid Manipulation for Biological Intervention - - - EUR 3 971 347,92 - - - United Kingdom - Germany - Sweden - Sweden - Belgium - Italy - United Kingdom - Sweden - Switzerland - Finland - United Kingdom - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - MMbio will bridge the classically separate disciplines of Chemistry and Biology by assembling leading experts from academia and non-academic partners (industry, technology transfer & science communication) to bring about - systems designed to interfere therapeutically with gene expression in living cells. Expertise in nucleic acid synthesis, its molecular recognition and chemical reactivity is combined with drug delivery, cellular biology and experimental medicine. - This project represents a concerted effort to make use of a basic and quantitative understanding of chemical interactions to develop and deliver oligonucleotide molecules of utility for therapy. Our chemical biology approach to this field is - ambitious in its breadth and represents a unqiues opportunity to educate young scientists across sectorial and disciplinary barriers. Training will naturally encompass a wide range of skills, requiring a joint effort of chemists and biologists to - introduce young researchers in a structured way to and array of research methodologies that no single research grouping could provide. The incorporation of early-stage and later stag ebiotechnology enterprises ensures that commercialisation of - methodologies as well as the drug development process is covered in this ITN. We hope that MMBio will train scientists able to understand both the biological problem and the chemistry that holds the possible solution and develop original experimental - approaches to stimulate European academic and commercial success in this area. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - MMBio - - - H2020-MSCA-ITN-2016 - - - 721613 - - - - - NEW BULGARIAN UNIVERSITY - TRAKIYSKI UNIVERSITET - PLOVDIVSKI UNIVERSITET PAISIY HILENDARSKI - MEDITCINSKY UNIVERSITET-PLOVDIV - UNIVERSITY OF RUSE ANGEL KANCHEV - Medical University Of Varna - JOINT INNOVATION CENTRE OF BAS - THE BRITISH COUNCIL - - - EUR 201 000 - - - Researchers in the Knowledge Triangle - - - EUR 248 645 - - - Bulgaria - Bulgaria - Bulgaria - Bulgaria - Bulgaria - Bulgaria - Bulgaria - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - - The K-TRIO 2 consortium organized in several years Researchers’ Night in Bulgaria in different cities making people and especially children and youth aware of researchers’ profession and the contribution of research to economy - and society. The public opinion surveys show that the Researchers’ Night became a popular event in many Bulgarian cities. People enjoy the variety of activities offered and would like to make the Researchers’ Night a regular “Fall rendez-vous” in - their city with a lot of fun and interaction with researchers. - - 2015-11-30, closed project - - - 2014-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.5."> - - - MSCA-NIGHT-2014 - European Researchers' Night (NIGHT) - - - CSA - Coordination and support action - - - Bulgaria - - - K-TRIO 2 - - - H2020-MSCA-NIGHT-2014 - - - 633175 - - - - - UNIVERSITY OF LEEDS - UNIVERSIDAD DE CANTABRIA - EIDGENOESSISCHE ANSTALT FUER WASSERVERSORGUNG ABWASSERREINIGUNG UND GEWAESSERSCHUTZ - NORSK INSTITUTT FOR VANNFORSKNING - THE UNIVERSITY OF BIRMINGHAM - FORSCHUNGSVERBUND BERLIN EV - STICHTING IHE DELFT - HELMHOLTZ-ZENTRUM FUER UMWELTFORSCHUNG GMBH - UFZ - UNIVERSITA DEGLI STUDI DI TRENTO - NATURAL ENVIRONMENT RESEARCH COUNCIL - - - EUR 3 923 988,84 - - - A EUROpean training and research network for environmental FLOW management in river basins - - - EUR 3 923 988,84 - - - United Kingdom - Spain - Switzerland - Norway - United Kingdom - Germany - Netherlands - Germany - Italy - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - - A EUROpean training and research network for environmental FLOW management in river basins - - 2021-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - EUROFLOW - - - H2020-MSCA-ITN-2017 - - - 765553 - - - - - PROCTER & GAMBLE TECHNICAL CENTRESLIMITED - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - THE UNIVERSITY OF BIRMINGHAM - UNIVERSITY OF BRISTOL - KATHOLIEKE UNIVERSITEIT LEUVEN - CONSORZIO INTERUNIVERSITARIO PER LO SVILUPPO DEI SISTEMI A GRANDE INTERFASE - UNIVERSITEIT GENT - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - PROCTER & GAMBLE SERVICES COMPANY NV - - - EUR 3 908 202,48 - - - BIOfilm management and CLEANing by leveraging fundamental understanding of biological, chemical and physical combined approaches - - - EUR 3 908 202,48 - - - United Kingdom - United Kingdom - United Kingdom - United Kingdom - Belgium - Italy - Belgium - Germany - Belgium - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - BIOCLEAN addresses the urgent need to create a sustainable training network across academia, industry and the healthcare sector which will fill the gap in Europe and beyond to produce highly skilled multi-disciplinary young - scientists competent in chemistry, engineering and experimental wet lab biology. BIOCLEAN will deliver this network of young scientists who can apply their proven skill sets gained during the project life time to solve industrial and healthcare - sector real life biofilm management challenges. - - 2020-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - BIOCLEAN - - - H2020-MSCA-ITN-2016 - - - 722871 - - - - - COVENTRY UNIVERSITY - EIGEN VERMOGEN VAN HET INSTITUUT VOOR LANDBOUW EN VISSERIJONDERZOEK - LUONNONVARAKESKUS - UNIVERSITAET FUER BODENKULTUR WIEN - RIJKSUNIVERSITEIT GRONINGEN - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - MINISTERIE VAN INFRASTRUCTUUR EN MILIEU - - - EUR 3 891 072,60 - - - Building Resourceful and Resilient Communities through Adaptive and Transformative Environmental Practice - - - EUR 3 891 072,60 - - - United Kingdom - Belgium - Finland - Austria - Netherlands - Germany - Netherlands - - - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - RECOMS will train 15 ESRs in transdisciplinary approaches to support resourceful and resilient community environmental practice, tackling societal challenges (e.g. food, energy and climate change), nurturing the potential of - stakeholders and vulnerable groupings to create adaptive and transformative sustainability pathways. RECOMS will increase the mobility of ESRs, enhance their Scientific, Professional, Personal and Transferable Skills and impact on their career - prospects as researchers, policy makers, facilitators, consultants, change agents, social innovators and environmental educators. The consortium of 7 beneficiaries and 4 partners comprised of public, private and non-profit organisations allows a - comparative approach to studying community resourcefulness across a range of (trans) national settings in 6 EU countries. Fundamental is the coupled social-ecological and critical lens to evolutionary resilience thinking, as complex, dynamic and - process based, denoting the capacity of a system to change. RECOMS raises capacities to implement practice-based solutions via 15 research projects, divided along 3 interconnected themes: Unlocking and Empowering; Adapting and Transforming; - Collaborating and Connecting. RECOMS addresses EU goals of sustainable and inclusive growth and territorial resource-based development, enhancing social cohesion and social innovation. The joint training organised in training events includes - integrated action-based learning, collaborative community practice, and experimenting with an assemblage of visual and creative interactive communication techniques. The joint training is complemented by online reflective learning portfolios, local - training at hosting institutes, the job-training via secondments and the support of Specialist Practitioner Advisors. RECOMS will impact on varied target groups including communities and policy-makers, and share its outcomes with non-participants via - a range of communication and dissemination activities. - - 2022-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - RECOMS - - - H2020-MSCA-ITN-2017 - - - 765389 - - - - - THE OPEN UNIVERSITY - OBSERVATOIRE DE PARIS - UNIVERSITY COLLEGE LONDON - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - INSTITUTO NACIONAL DE TECNICA AEROESPACIAL ESTEBAN TERRADAS - STICHTING VU - SCIENOFFICE, COMUNICACAO DE CIENCIA LDA - OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN - INTERNATIONAL RESEARCH SCHOOL OF PLANETARY SCIENCES - ILMATIETEEN LAITOS - DEUTSCHES ZENTRUM FUER LUFT - UND RAUMFAHRT EV - ABERYSTWYTH UNIVERSITY - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - NATURAL HISTORY MUSEUM - JACOBS UNIVERSITY BREMEN GGMBH - ISTITUTO NAZIONALE DI ASTROFISICA - AARHUS UNIVERSITET - MAGYAR TUDOMANYOS AKADEMIA WIGNER FIZIKAI KUTATOKOZPONT - USTAV FYZIKY ATMOSFERY AV CR, v.v.i. - MATIS OHF - WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER - FONDATION EUROPEENNE DE LA SCIENCE - GFI INFORMATIQUE SA - CORIOLYS - MEDIZINISCHE UNIVERSITAT GRAZ - INSTITUT ROYAL D'AERONOMIE SPATIALEDE BELGIQUE - LATVIJAS UNIVERSITATE - UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA - INSTYTUT NAUK GEOLOGICZNYCH POLSKIEJ AKADEMII NAUK - VILNIAUS UNIVERSITETAS - INSTITUTE OF ACCELERATING SYSTEMS AND APPLICATIONS - UNIVERSITEIT LEIDEN - CENTRUM BADAN KOSMICZNYCH POLSKIEJ AKADEMII NAUK - STIFTUNG INTERNATIONAL SPACE SCIENCE INSTITUTE - - - EUR 9 945 361 - - - EUROPLANET 2020 Research Infrastructure - - - EUR 10 234 226,05 - - - United Kingdom - France - United Kingdom - France - Spain - Netherlands - Portugal - Austria - Italy - Finland - Germany - United Kingdom - Germany - United Kingdom - Germany - Italy - Denmark - Hungary - Czech Republic - Iceland - Germany - France - France - France - Austria - Belgium - Latvia - Spain - Poland - Lithuania - Greece - Netherlands - Poland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - - The Europlanet 2020 Research Infrastructure (EPN2020-RI) will address key scientific and technological challenges facing modern planetary science by providing open access to state-of-the-art research data, models and - facilities across the European Research Area. Its Transnational Access activities will provide access to world-leading laboratory facilities that simulate conditions found on planetary bodies as well as specific analogue field sites for Mars, Europa - and Titan. Its Virtual Access activities will make available the diverse datasets and visualisation tools needed for comparing and understanding planetary environments in the Solar System and beyond. By providing the underpinning facilities that - European planetary scientists need to conduct their research, EPN2020-RI will create cooperation and effective synergies between its different components: space exploration, ground-based observations, laboratory and field experiments, numerical - modelling, and technology. - - 2019-08-31, ongoing project | - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.2."> - - - INFRAIA-1-2014-2015 - Integrating and opening existing national and regional research infrastructures of European interest - - - RIA - Research and Innovation action - - - United Kingdom - - - EPN2020-RI - - - H2020-INFRAIA-2014-2015 - - - 654208 - - - - - THE UNIVERSITY OF BIRMINGHAM - - - EUR 195 454,80 - - - Advanced catalyst electrodes from Ionic liquid modified PtNi nanowire arrays for PEFCs - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Recent developments in PEFC research have seen a significant enhancement of catalyst activities and a reduction of cost at a reduced loading of precious metals by employing novel Pt-based extended surface area nanostructures - alloyed with transitional metals, but the low stability caused by the easy dissolution of transitional metals in acidic PEFC environment, and the large difficulty to be integrated into devices due to the unconventional morphology of extended surface - area nanostructures as Pt/C nanoparticle catalysts limit them mainly to pure material research, resulting in an increasing gap with real high performance devices. - - - 2019-08-02, ongoing project - - - 2017-08-03 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - IonPEFC - - - H2020-MSCA-IF-2016 - - - 739940 - - - - - TEL AVIV UNIVERSITY - THE UNIVERSITY OF WARWICK - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - UNIVERSITEIT TWENTE - BERGISCHE UNIVERSITAET WUPPERTAL - UNIVERSITE DE FRANCHE-COMTE - UNIVERSITE DE BORDEAUX - THE UNIVERSITY OF EXETER - UNIVERSIDAD AUTONOMA DE MADRID - FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG - - - EUR 3 932 721,72 - - - Control of flexible structures and fluid-structure interactions - - - EUR 3 932 721,72 - - - Israel - United Kingdom - United Kingdom - Netherlands - Germany - France - France - United Kingdom - Spain - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - We propose to develop systems and control theory needed to understand and control large flexible structures and fluid structure interactions. The beneficiaries are a group of 15 academics from the fields of modelling, control - theory, distributed parameter systems and fluid dynamics, aeroelasticity, swimming and marine engineering, working in either mathematics or engineering departments, with strong links between us. We are located at 10 universities in the UK, France, - The Netherlands, Spain, Germany and Israel. In addition, we have four partner universities in Canada, China, USA and France and 11 prestigious industry partners, mostly from Europe. We believe that our backgrounds and skills are sufficiently close so - that we can (and do) communicate with ease, but also sufficiently distinct so that we can cover many aspects of this field, and hence (as a consortium) offer outstanding training to young researchers. We believe that this area will have a great - impact on the technology of the future, as well as on our understanding of nature, and we are eager to train new scientists and engineers in this broad field. We believe that Science and Technology in Europe will greatly benefit from this research, - and from the education and and knowledge that we will impart to a new generation of researchers. Our research plans are organized into five scientific work packages, which cover mathematical systems theory, modelling and model reduction, relevant - aspects of control theory, and applications. The applications that we plan to investigate concern a wide range of flexible structures in interaction with fluids: wind turbines, aircraft wings, precision machine tools, vessels linked by cables as - encountered in marine salvage operations and microscopic electromechanical devices. These apparently unrelated systems face similar challenges and can be analysed and controlled in a unified framework. - - 2021-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Israel - - - ConFlex - - - H2020-MSCA-ITN-2017 - - - 765579 - - - - - TECHNISCHE UNIVERSITAET BRAUNSCHWEIG - - - EUR 159 460,80 - - - SINGLE-MOLECULE DNA SEQUENCING THROUGH DNA ORIGAMI NANOANTENNAS. - - - EUR 159 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - The inner working of many fundamental biological nanomachines implies many stochastic changes in conformation and molecular interactions. These changes are reflected as variability in the activity of the same molecule over - time, and in heterogeneous activities between different molecules. By the direct observation at the molecular scale of these nanomachines activity, single-molecule fluorescence techniques have gained access to this stochastic information, which is - otherwise missed by bulk techniques but is essential for their understanding. However, the widespread use of these techniques in many biological systems has been hampered by the low working concentration (nM) determined by the diffraction limit of - light, and current nanophotonic solutions to this problem are technically too demanding. Here, we propose self-assembled DNA origami nanoantennas as nanophotonic platforms aiming to break this concentration barrier by means of fluorescence signal - enhancing and reduction of the observation volume. The versatility of DNA origami structures, biocompatibility and ability for site-directed immobilization of biomolecules, make them perfectly suited to perform complex biological assays. In the - presented action we aim to achieve single-molecule fluorescence DNA sequencing using DNA origami nanoantennas to probe the potential of these platforms to perform complex bioassays, in the high concentration regime and demanding multiplexing. - Moreover, since they avoid the fabrication and instrumental challenges related to other nanophotonic devices, self-assembly DNA origami nanoantennas are amenable, easy to handle and friendly technology to the biological experimenter, and thus we - expect to boost their use in biology. Besides, the fulfilment of this action will provide the fellow with a complete formative training that would boost his future scientific career, and will generate also a new DNA-sequencing technology that will - impact positively European scientific excellence. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - Origami-SEQ - - - H2020-MSCA-IF-2016 - - - 746635 - - - - - QUEEN MARY UNIVERSITY OF LONDON - - - EUR 195 454,80 - - - Light-addressable potentiometric sensors (LAPS) for zinc imaging with high spatiotemporalresolution for elucidating the role of zinc in age related macular degeneration. - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Light-addressable potentiometric sensors (LAPS) have great potential as a tool for functional electrochemical imaging of the attachment area of cells, providing information such as ion concentration, extracellular potentials - and ion channel activity. The technique is particularly attractive for analysing cell responses of cells with planar polarisation as the cell-surface attachment area is not accessible to conventional electrophysiological measurements. However, - current systems suffer either from poor resolution or slow scanning speed. In this project, we propose to develop a novel LAPS setup with high spatiotemporal resolution combined with two-photon fluorescence microscopy that allows imaging of - physiological processes with submicron resolution and in real time. Novel zinc sensitive surfaces will be developed and used in conjunction with the new high-resolution and high-speed LAPS setup to investigate the role of zinc in age related macular - degeneration (AMD). The retina and the underlying retinal pigment epithelium contain high concentrations of zinc. Several eye disorders are associated with altered zinc balance, and zinc supplementation has become a choice of treatment for diseases - like agerelated macular degeneration. Despite its importance in health and diseases of the eye, it is still not well understood how zinc participates in cellular and molecular events and how zinc supplementation might be beneficial. We will - investigate zinc fluxes at the basal side of the retinal pigment epithelium where zinc is suspected to play a key role in the formation of deposits and the initiation of AMD. The results of the study may lead to new treatments to prevent, forestall, - or reverse the effects of the disease and may also help to elucidate zinc's role in other diseases including type 2 diabetes, pancreatic cancer, and Alzheimer disease and are therefore expected to impact the pharmaceutical industry and increase the - quality of life for an ageing population. - - 2019-06-20, ongoing project - - - 2017-06-21 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ZINCLAPS - - - H2020-MSCA-IF-2016 - - - 745820 - - - - - UNIVERSITAT DE BARCELONA - TECHNISCHE UNIVERSITAET BRAUNSCHWEIG - UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA - EXPERT YMAGING SL - AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH - MEDIZINISCHE UNIVERSITAET WIEN - FONDATION SUISSE POUR LA RECHERCHEEN MICROTECHNIQUE - - - EUR 3 759 790 - - - Overcoming the Limits of Diffraction with Superresolution Lighting on a Chip - - - EUR 3 759 790 - - - Spain - Germany - Italy - Spain - Austria - Austria - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - - The physical laws of diffraction generally limit the spatial resolution of optical systems, being about 200 nm for light in the visible range. Within ChipScope we want to overcome this limit by developing the scientific and - technological basis for a completely new approach to optical superresolution, based on semiconductor nano Light Emitting Diode (nanoLED) arrays with individual pixel operation. The core idea of ChipScope is to use spatially resolved illumination - instead of spatially resolved detection for achieving microscopy functionality with superresolution. This will be made possible by developing chip-based nanoLED arrays with light emitting diode (LED) dimensions and distances much smaller than the - wavelength of visible light (i.e. <50 nm). Thus, ChipScope will develop the highest resolution LED arrays in the world. These new devices will enable novel science in general and superresolution in particular. Making optical superresolution - ubiquitously available is expected to lead to foundational breakthroughs in virtually every field of research and technology that makes use of optical microscopes. Within the project, the first chip-sized “ChipScope microscopes” will be developed, - tested, calibrated and compared with state-of-the-art microscopy systems. During the course of the project, a game changing real-time imaging device for scientific investigation of living tissue will be used to study the in-cell mechanisms in Chronic - Obstructive Pulmonary Disease (COPD) syndrome as a proof-of-concept of the new science and applications that will follow. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-01-2016-2017 - FET-Open research and innovation actions - - - RIA - Research and Innovation action - - - Spain - - - ChipScope - - - H2020-FETOPEN-1-2016-2017 - - - 737089 - - - - - ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM - KATHOLIEKE UNIVERSITEIT LEUVEN - IRCCS AZIENDA OSPEDALIERA UNIVERSITARIA SAN MARTINO-IST-ISTITUTO NAZIONALE PER LA RICERCA SUL CANCRO - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - KLINIKUM DER UNIVERSITAET ZU KOELN - THE ROYAL VETERINARY COLLEGE - SURGACOLL TECHNOLOGIES LIMITED - LIFETEC GROUP BV - - - EUR 3 607 596,36 - - - Controlling Cartilage to Bone Transitions for Improved Treatment of Bone Defects and Osteoarthritis - - - EUR 3 607 596,36 - - - Netherlands - Belgium - Italy - Ireland - Germany - United Kingdom - Ireland - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - A well-functioning locomotor system is essential for human well-being. This is an important consideration in our aging population with the increased associated costs of ensuring high quality of life. Many people suffer from - diseases of the locomotor system, such as bone defects or osteoarthritis, for which current treatments are insufficient. To develop new treatments, CarBon includes 6 academic partners, 3 companies and 3 charitable foundations, working together to - train 14 young scientists. We will combine knowledge from the fields of tissue engineering, cartilage and bone developmental biology and pathobiology using skills from the disciplines of cell biology, computational modelling, biotechnology - (bioreactors, biomaterials) and drug discovery. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Netherlands - - - CarBon - - - H2020-MSCA-ITN-2016 - - - 721432 - - - - - UNIVERSITY STEFAN CEL MARE SUCEAVA - JOHANNES GUTENBERG-UNIVERSITAT MAINZ - UNIVERSITAT DE VALENCIA - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - INSTITUTUL DE CHIMIE MACROMOLECULARA PETRU PONI - UKRORGSYNTEZ - SRL POLIVALENT-95 - - - EUR 954 000 - - - Multifunctional Spin Crossover Materials - - - EUR 954 000 - - - Romania - Germany - Spain - France - Romania - Ukraine - Moldova - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - This project deals with an exchange programme of seven research teams with the aim to establish and consolidate a network for the design of innovative multifunctional materials based upon iron(II) spin crossover complexes: - their synthesis, magnetic and spectroscopic studies, investigations on their crystalline, liquid crystalline and morphological structures, pressure effects on spin crossover properties and, particularly, their implementation into pressure sensors. - The synthetic part of this project aims to access novel types of crystalline and liquid crystalline spin crossover complexes, hybrid luminescent materials, photo-switchable liquid crystalline compounds, composites and nano-objects of original - morphologies and transition characteristics. These switchable materials will become a matter of different experiments under pressure: magnetic and Mӧssbauer measurements under hydrostatic pressure and optical experiments in a gas pressure cell. This - will allow to reach an important impact on the synthesis of new bistable materials, on their behaviour under pressure, and to make them an active part of different pressure sensors. The academic participants involved in this work have collaborated on - joint projects and have co-authored several scientific papers. The two industrial institutions have a recognized expertise in organic and material synthesis, commercialization, as well possessing experience on elaboration of spin transition - materials. The establishment of this joint exchange programme will promote and strengthen the complementarity of the participants and will stimulate cross-fertilization, thus forming an excellent centre of synergy in research, innovation and - technology in the area of functional materials. This network offers a complete training in the synthesis and characterization of new spin crossover materials for various applications. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Romania - - - SPINSWITCH - - - H2020-MSCA-RISE-2016 - - - 734322 - - - - - CONSIGLIO NAZIONALE DELLE RICERCHE - ATHINA-EREVNITIKO KENTRO KAINOTOMIAS STIS TECHNOLOGIES TIS PLIROFOFORIAS, TON EPIKOLNONION KAI TIS GNOSIS - UNIWERSYTET WARSZAWSKI - JISC LBG - UNIVERSITAET BREMEN - UNIVERSIDADE DO MINHO - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - PIN SOC.CONS. A R.L. - SERVIZI DIDATTICI E SCIENTIFICI PER L UNIVERSITA DI FIRENZE - INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH - INTERNATIONAL CENTER FOR RESEARCH ON THE ENVIRONMENT AND THE ECONOMY - - - EUR 1 997 837,50 - - - OpenAIRE - CONNECTing scientific results in support of Open Science - - - EUR 1 997 837,50 - - - Italy - Greece - Poland - United Kingdom - Germany - Portugal - France - Italy - France - Switzerland - Greece - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Other - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Other - - Open Science is around the corner. Scientists and organizations see it as a way to speed up, improve quality and reward, while policy makers see it as a means to optimize cost of science and leverage innovation. Open Science - is an emerging vision, a way of thinking, whose challenges always gaze beyond its actual achievements. De facto, today’s scientific communication ecosystem lacks tools and practices to allow researchers to fully embrace Open Science. OpenAIRE-Connect - aims to provide technological and social bridges, and deliver services enabling uniform exchange of research artefacts (literature, data, and methods), with semantic links between them, across research communities and content providers in scientific - communication. It will introduce and implement the concept of Open Science as a Service (OSaaS) on top of the existing OpenAIRE infrastructure, delivering out-of-the-box, on-demand deployable tools. OpenAIRE-Connect will adopt an end-user driven - approach (via the involvement of 5 prominent research communities), and enrich the portfolio of OpenAIRE infrastructure production services with a Research Community Dashboard Service and a Catch-All Notification Broker Service. The first will offer - publishing, interlinking, packaging functionalities to enable them to share and re-use their research artifacts (introducing “methods, e.g. data,software, protocols). This effort, supported by the harvesting and mining “intelligence” of the OpenAIRE - infrastructure, will provide communities with the content and tools they need to effectively evaluate and reproduce science. OpenAIRE-Connect will combine dissemination and training with OpenAIRE’s powerful NOAD network engaging research communities - and content providers in adopting such services. These combined actions will bring immediate and long-term benefits to scholarly communication stakeholders by affecting the way research results are disseminated, exchanged, evaluated, and re-used. - - 2019-06-30, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.3."> - - - EINFRA-22-2016 - User-driven e-infrastructure innovation - - - RIA - Research and Innovation action - - - Italy - - - OpenAIRE-Connect - - - H2020-EINFRA-2016-1 - - - 731011 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 2 499 761 - - - Exoribonuclease-mediated degradation of nascent RNA in Malaria Parasites: A Novel Mechanism in Virulence Gene Silencing - - - EUR 2 499 761 - - - France - France - - - Research Organisations - Research Organisations - - Background: The human protozoan malaria parasite P. falciparum causes approximately 200 million infections and 0.7 million deaths (mainly children) per year. In the well-studied asexual blood stages, cyclic monocistronic gene - activation occurs at the transcriptional level; however, relatively few transcription factors have been identified, thus other types of regulatory processes that contribute to this coordinated gene expression are believed to exist. Through the study - of molecular process of monoallelic expression of immune evasion genes in P. falciparum (project funded by a previous ERC grant to A. Scherf), we discovered an entirely new mechanism of gene silencing. We demonstrated that an exoribonuclease silences - genes linked to severe malaria. A non-canonical 3’-5’exoribonuclease termed PfRNase II destroys nascent RNA made from promoter regions, leading to cryptic unstable mRNA. Parasites carrying a deficient PfRNase II produce full-length mRNA and long - noncoding RNA. The molecular events and the number of genes directly controlled by this novel type of posttranscriptional gene silencing remain elusive. - - - 2020-10-31, ongoing project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - France - - - PlasmoSilencing - - - ERC-2014-ADG - - - 670301 - - - - - THE UNIVERSITY OF WARWICK - - - EUR 195 454,80 - - - Multi-functional DUAL PHOSphorus-based organoCATalysts for stereoselective ring-opening polymerisation - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The stereocontrolled ring-opening polymerisation (ROP) of chiral cyclic esters for the preparation of biodegradable polymers with precise and finely-tuned properties remains a research challenge. Only Few catalysts/initiators - have been reported to produce stereoregular high molecular weight polymers; most of them being highly sensitive and/or toxic organometallic species. Organocatalysed ROP produces polymers that are free of residual metal contaminates but to date, does - not allow high productivities with high levels of stereocontrol. In this context, the multi-disciplinary proposal DUAL-PHOSCAT proposes to develop chiral tunable dual phosphorus-based organocatalysts to overcome these challenges. For this, a - stepwise-synthesis strategy to tailor the organocatalyst architectures and an inventive combinatorial approach using self-assembled oganocatalysts will be investigated. The stepwise synthesis will bind together using chiral linkers, chiral - phosphorus-based molecules and chiral thioureas molecules.The self-assembled dual organocatalysts will be obtained combining chiral amine-thioureas and chiral phosphoric acids. These systems will be investigated for the ROP of rac-lactide and - rac-beta-butyrolactone. The proposed catalysts enable great advances in the preparation of isotactic polylactide (PLA) stereocomplex and highly tactic poly-3-hydroxybutyrate (PHB) in terms of catalyst stability, productivity, activity and - stereoselectivity, in turn making these catalysts efficient green alternative to sensitive and /or toxic organometallic initiators for the synthesis of metal-free highly stereoregular polyesters under industrially-relevant conditions. The PLA and PHB - obtained will find potential applications in packaging and fibers (as green alternative to petroleum-based plastics) or as biomedical devices that is in line with the H2020 programme (e.g. Climate action, environment, resource efficiency and raw - materials and Health, Demographic and well-being). - - 2019-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - United Kingdom - - - DUAL-PHOSCAT - - - H2020-MSCA-IF-2016 - - - 752405 - - - - - SLOVENSKA ORGANIZACIA PRE VYSKUMNEA VYVOJOVE AKTIVITY ZDRUZENIE - SLOVENSKA AKADEMIA VIED - I-EUROPA SRO - CENTRUM VEDECKO TECHNICKYCH INFORMACII SLOVENSKEJ REPUBLIKY - - - EUR 248 300 - - - Festival of Science European Researchers´ Night 2016 - 2017 in Slovakia - - - EUR 347 700 - - - Slovakia - Slovakia - Slovakia - Slovakia - - - Other - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - European Researchers` Night has been successfully implemented 9times and has covered 4 from 8 regions all over Slovakia. In 2015 it took place in 6 cities, the event featured nearly 1.000 researchers and was attended by up to - 160.000 visitors. Thanks to interactive presentations of scientific work and research, in very friendly and informal atmosphere, we managed to increase the interest and augmented awareness of science in general public. The main objective is to inform - the general public about the inconspicuous, yet fundamental influence of the scientists within the society and to present their outcomes, which are crucial for society. The project supports also the area of regional development and intensifies - interaction between hundreds of scientists. The concept for ERN 2016-2017 will have common themes to all venues and locations in Slovakia: Experience the Science (2016) and Science is the story (2017). Active participation of researchers from - different institutions, various fields, focusing on various subjects of research will create great platform for showing young people how lively and impulsive could scientific career be. People will have an opportunity to spend all day visiting - different presentations and stands, lectures and discussions, testing scientific applications, and getting in touch with real researchers. Thanks to these direct exchanges and discussions they can discover the "human face" of researchers and are more - likely to remember their successes or stories. In 2016 we intend to prepare exceptional and bigger event in regard to 10th anniversary of ERN in Slovakia as well as the Slovak Presidency of EU Council. Unique celebration of science will be supported - by various pre events and teasers and engaged more cultural institutions. Presidency of EU Council will also offer additional space for promoting ERN event as crucial part of enhancing the visibility of the Slovak and EU research. - - 2017-11-30, closed project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.5."> - - - MSCA-NIGHT-2016 - European Researchers' Night - - - CSA - Coordination and support action - - - Slovakia - - - ERN16-17 SVK - - - H2020-MSCA-NIGHT-2016 - - - 723000 - - - - - UNIVERSITATEA POLITEHNICA DIN BUCURESTI - UNIVERSITATEA POLITEHNICA DIN BUCURESTI - - - EUR 185 925 - - - Radio wave propagation in heterogeneous media: implications on the electronics of Cosmic Neutrino Detectors - - - EUR 185 925 - - - Romania - Romania - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Detection of cosmic neutrinos can answer very important questions related to some extremely energetic yet unexplained astrophysical sources such as: compact binary stars, accreting black holes, supernovae etc., key elements in - understanding the evolution and fate of the Universe. Moreover, these particles carry the highest - - 2018-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Romania - - - CosNeD - - - ERC-2016-STG - - - 714637 - - - - - UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6 - CENTRO DE CIENCIAS DO MAR DO ALGARVE - NATURAL ENVIRONMENT RESEARCH COUNCIL - THE SCOTTISH ASSOCIATION FOR MARINESCIENCE LBG - STAZIONE ZOOLOGICA ANTON DOHRN - MARINE SCOTLAND - MARINE BIOLOGICAL ASSOCIATION OF THE UNITED KINGDOM - FORSCHUNGSVERBUND BERLIN EV - CONSIGLIO NAZIONALE DELLE RICERCHE - THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS - TUNATECH GMBH - XELECT LIMITED - INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE - UNIVERSITETET I TROMSOE - CAB INTERNATIONAL - UNIVERSITEIT GENT - INSTITUT PASTEUR - HELMHOLTZ-ZENTRUM FUER INFEKTIONSFORSCHUNG GMBH - EUROPEAN MOLECULAR BIOLOGY LABORATORY - UNIVERSITE DE MARNE LA VALLEE - TEL AVIV UNIVERSITY - UNIVERSITE DE NICE SOPHIA ANTIPOLIS - SCALPRO AS - LEIBNIZ-INSTITUT DSMZ-DEUTSCHE SAMMLUNG VON MIKROORGANISMEN UND ZELLKULTUREN GMBH* - HELLENIC CENTRE FOR MARINE RESEARCH - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSITETET I BERGEN - - - EUR 9 041 611 - - - European Marine Biological Research Infrastructure Cluster to promote the Blue Bioeconomy - - - EUR 9 041 611 - - - France - Portugal - United Kingdom - United Kingdom - Italy - United Kingdom - United Kingdom - Germany - Italy - United Kingdom - Germany - United Kingdom - France - Norway - United Kingdom - Belgium - France - Germany - Germany - France - Israel - France - Norway - Germany - Greece - France - Norway - - - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - - Marine (blue) biotechnology is the key to unlocking the huge economic potential of the unique biodiversity of marine organisms. This potential remains largely underexploited due to lack of connectivity between research - services, practical and cultural difficulties in connecting science with industry, and high fragmentation of regional research, development and innovation (RDI) policies. To overcome these barriers, EMBRIC (European Marine Biological Resource - Infrastructure Cluster) will link biological and social science research infrastructures (EMBRC, MIRRI, EU-OPENSCREEN, ELIXIR, AQUAEXCEL, RISIS) and will build inter-connectivity along three dimensions: science, industry and regions. The objectives - of EMBRIC are to: (1) develop integrated workflows of high quality services for access to biological, analytical and data resources, and deploy common underpinning technologies and practices; (2) strengthen the connection of science with industry by - engaging companies and by federating technology transfer (TT) services; (3) defragment RDI policies and involve maritime regions with the construction of EMBRIC. Acceleration of the pace of scientific discovery and innovation from marine bioresources - will be achieved through: (i) establishment of multidisciplinary service-oriented technological workflows; (ii) joint development activities focusing on bioprospection for novel marine natural products, and marker-assisted selection in aquaculture; - (iii) training and knowledge transfer; (iv) pilot transnational access to cluster facilities and services. EMBRIC will also connect TT officers from contrasted maritime regions to promote greater cohesion in TT practices. It will engage with - policy-makers with the aim of consolidating a perennial pan-European virtual infrastructure cluster rooted in the maritime regions of Europe and underpinning the blue bioeconomy. - - 2019-05-31, ongoing project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-4-2014-2015 - Implementation and operation of cross-cutting services and solutions for clusters of ESFRI and other relevant research infrastructure initiatives - - - RIA - Research and Innovation action - - - France - - - EMBRIC - - - H2020-INFRADEV-1-2014-1 - - - 654008 - - - - - INSTITUT PASTEUR - - - EUR 185 076 - - - Mechanisms of α-synuclein spreading, implications for synucleinopathies - - - EUR 185 076 - - - France - - - Research Organisations - - A common feature of neurodegenerative diseases, including highly prevalent illnesses, is the presence of misfolded protein aggregates in affected regions of the nervous system. Aggregates result from the misfolding of one or - more specific proteins, for example, amyloid-β in Alzheimer’s disease, α-synuclein in Parkinson’s disease, and the normal prion protein in transmissible spongiform encephalopathies (TSEs). Recently a series of exciting studies has suggested a - prion-like mechanism underlying the pathological spreading of misfolded proteins (mainly tau, α-synuclein and huntingtin) involved in various neurodegenerative diseases. Particularly striking is the recovery of α-synuclein aggregates from engrafted - embryonic neurons in post-mortem brains transplanted from Parkinson’s patients. Thus, while questioning the therapeutic use of transplants, the understanding of the molecular and cellular fundaments of cell-to-cell transmission of proteinaceous - aggregates is clearly in the early stages of investigation and may represent a more readily accessible target for novel disease-modifying therapies, allowing the development of possible common therapeutic strategies. - - - 2018-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - NEUROTUNN - - - H2020-MSCA-IF-2015 - - - 702465 - - - - - INSTITUT PASTEUR - - - EUR 185 076 - - - Interaction between gut-microbiota and the central stress system in cognitive alterations associated with aging. - - - EUR 185 076 - - - France - - - Research Organisations - - Aging drives cognitive impairment and general health demise increasing the susceptibility to neurodegenerative disorders in healthy individuals. It is also associated with changes in the gut-microbiota and a general increase - in the secretion of stress hormones, known to have debilitating effects when sustained. The gut-microbiota has recently emerged has a crucial modulator of cognitive abilities and general health. Nonetheless, the causes and consequences of the - gut-microbiota changes seen in aging are currently unknown. In this application, we propose to study the importance of the age-associated gut-microbiota changes on brain functions, by swapping the gut-microbiota from aged mice into young mice and - vice-versa. This will allow knowing the contribution of the gut-microbiota in the cognitive decline and depressive state associated with aging. Furthermore, we will test if the increase in stress hormones known to occur during aging are upstream of - those age-associated microbiota changes, by testing the involvement of the amygdala to the hypothalamus-adrenal axis in this phenomena. This will be achieved by using a chemo-genetic approach to control the activation of each component of this - pathway. This project will provide the first description of the functional repercussions of the age-associated changes in the gut-microbiota composition on learning and memory deficits and depression, and possibly elucidate one of the upstream - mechanisms responsible. The outcome of this work will pave the way toward the elaboration of probiotic treatments against the detrimental effect of aging. - - 2018-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - Microbiota and aging - - - H2020-MSCA-IF-2015 - - - 708466 - - - - - UNIVERSITETET I STAVANGER - HELSINGIN YLIOPISTO - BOURNEMOUTH UNIVERSITY - TYOTERVEYSLAITOS - PROFESSIONSHOJSKOLEN ABSALON S/I - HOGSKOLEN I MOLDE - KRIMINALOMSORGSDIREKTORATET - STICHTING FORENSISCH PSYCHIATRISCHCENTRUM DR. S. VAN MESDAG - FOOTPRINTS PROJECT - - - EUR 445 500 - - - Improving collaborative working between correctional and mental health services - - - EUR 445 500 - - - Norway - Finland - United Kingdom - Finland - Denmark - Norway - Norway - Netherlands - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Other - Other - - Effective collaboration between mental health (MHS) and correctional services (CS) impacts on mental illness and reduces reoffending rates. Service leaders have indicated a need for more effective models of collaboration. - Researchers have identified the Change Laboratory Model (CLM) of workplace transformation as a more effective means of supporting interagency collaborative practice than current integration tools. It provides a way to optimise the effectiveness of - mental healthcare provision to offenders through a model that fosters innovation and collaborative processes. However, the change laboratory, highly successful internationally and in other clinical contexts, is a new idea in prison development, none - as yet being applied to the challenges facing the MHS and CS. The wickedness, complexity and unpredictability of challenges facing interagency working in these secure environments means that piloting the CLM is premature and it must first be adapted - to the MHS/CS context. The aim of this study is to validate the change laboratory model ready for implementation in practice. This RISE application builds a community of practice that enriches international research capacity and cooperation to - achieve this aim. It brings academic knowledge of the Change Laboratory model to the market of interagency practices between mental health and correctional services for the development of innovation and the advancement of integrated service provision - to mentally ill offenders. Knowledge exchange takes place through secondments, interactive workshops, the development of workforce training programmes, study tours, shadowing opportunities and ethnographic research. Through this knowledge exchange, - the consortium delivers a user-informed prototype of change laboratory model ready for implementation in the MHS and CS field. This validated change laboratory model, offers the ERA a clear strategy with which to promote integrated care for mentally - ill offenders. - - 2021-01-31, ongoing project - - - 2017-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Norway - - - CO-LAB - - - H2020-MSCA-RISE-2016 - - - 734536 - - - - - INSTITUT PASTEUR - - - EUR 173 076 - - - Labeling Flavivirus capsid protein to unravel its dynamics during infection and egress by correlative super-resolution fluorescence and cryo-electron microscopy - - - EUR 173 076 - - - France - - - Research Organisations - - Vector-borne diseases are major worldwide threats. Specifically, mosquito-borne diseases from the flavivirus genus such as West Nile and dengue viruses are raising major concerns on human health. There are few or no - treatment/vaccine strategies to fight these viruses and the relatively poor knowledge of their life cycle (entry and egress) contributes to the deficit in treatment possibilities. A deeper knowledge of the virus cycle is required to unlock the - development of antivirals. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - FLAVIC DYNAMICS - - - H2020-MSCA-IF-2015 - - - 703519 - - - - - INSTITUT PASTEUR - - - EUR 185 076 - - - Dissecting dsRNA uptake in RNAi-based antiviral immunity - - - EUR 185 076 - - - France - - - Research Organisations - - Important viral infectious diseases, such as dengue and chikungunya, are transmitted to humans by insect vectors. One of the key factors that modulates whether an insect is competent or not to transmit a given pathogen is its - innate immune response. The major antiviral defense in insects is the RNA interference (RNAi) mechanism that is activated by the detection of viral double-stranded RNA (dsRNA). During antiviral RNAi a silencing immune signal is transported from one - cell to another to set an antiviral state (systemic RNAi). To be primed, non-infected cells must sense this silencing signal and internalize it. Although dsRNA as a mediator of local antiviral immunity is well established in insects, the effectors of - a systemic immune response are not identified. For instance, the identification of the dsRNA receptor in insects remains elusive. This proposal intends to dissect the mechanism of dsRNA uptake in insects with special focus on discovering its - receptor. I propose to combine functional (genome wide RNAi screen, in vivo dsRNA oral uptake) with binding (electrophoretic mobility shift assay, surface plasmon resonance) and structural assays (expression, production and studies of complexes - receptor/dsRNA) using Drosophila melanogaster as insect model and an array of viruses in order to identify and characterize the dsRNA receptor.To be found, the manipulation of this receptor could help control the insect vectors of emerging viral - diseases. Understanding how the infection is controlled within the insect before crossover to the human host could generate new strategies to disrupt pathogen transmission. - - 2017-05-31, closed project | - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - DDRR - - - H2020-MSCA-IF-2014 - - - 656398 - - - - - INSTITUT PASTEUR - - - EUR 185 076 - - - Glucose metabolism and mTOR pathway role in CD8+ T cell control of HIV-1 - - - EUR 185 076 - - - France - - - Research Organisations - - Antiretroviral therapy can decrease HIV-1 below the limit of detection but fails to eliminate the virus completely. One of the main goals of a HIV-1 vaccine is the generation of cytotoxic CD8 T cell responses that counteract - the virus. CD8 T cells participate in the control of viremia early but progressively show weakened functions, which leads to loss of virus control. HIV controllers are a rare group of infected patients who can control the virus for years without - antiretroviral therapy. CD8 T cells from HIV-controllers display an outstanding capacity to eliminate infected CD4 T cells ex vivo but the underlying mechanisms are still not understood. - - 2018-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - France - - - GLUTORHIV - - - H2020-MSCA-IF-2015 - - - 706871 - - - - - INSTITUT PASTEUR - INSTITUT PASTEUR - - - EUR 1 791 250 - - - Mechanisms of epigenetic inheritance by short RNAs - - - EUR 1 791 250 - - - France - France - - - Research Organisations - Research Organisations - - Epigenetic mechanisms are considered to be central to the development of multicellular organisms made of different cell types, all having identical genomes. Similarly, they may explain how genetically identical organisms are - capable of adapting to distinct environmental conditions. Yet, the molecular mechanisms regulating how epigenetic traits can be inherited during cell division or across generations are not fully understood. Using the nematode Caenorhabditis elegans, - we have recently revealed how the nuclear Argonaute protein CSR-1 and its associated short RNAs participate in global transcriptional regulation and chromatin organization. This unprecedented observation opened up a new class of molecular mechanisms - by which Argonaute proteins and their bound short RNAs may actively contribute to epigenetic inheritance in animals. - - 2021-01-31, ongoing project - - - 2016-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - RNAEPIGEN - - - ERC-2015-STG - - - 679243 - - - - - INSTITUT PASTEUR - INSTITUT PASTEUR - - - EUR 1 976 100 - - - Perivascular cells at the crossroads of inflammation, regeneration and fibrosis - - - EUR 1 976 100 - - - France - France - - - Research Organisations - Research Organisations - - The survival of organisms requires the ability to repair tissues upon injury, as well as, after birth, to fight foreign invaders that may have contaminated the wound. This last function is mediated by a complex host response - involving immune cells, blood vessels and inflammatory mediators that collectively intend to neutralize the harmful agent and eliminate damaged/necrotic tissue. Initially beneficial, this massive inflammatory response comes with a cost, and adult - injured tissues usually heal with a scar, which is an area of fibrous tissue that transiently replaces normal tissue. In chronic settings, scarring can become excessive in a process called fibrosis, to the point of preventing functional recovery of - the injured organ and be life threatening. Nearly half of all deaths in industrialized world are due to diseases involving inappropriate, often chronic, inflammatory and fibrotic responses, including lung, kidney and liver diseases, scleroderma, - inflammatory bowel diseases, muscular dystrophies, cardiovascular diseases, and tumors. However our current knowledge of the biological processes regulating fibrosis is partial, which has hindered therapeutic advances in the field. Recent data from - our team and others drew new attention on a discrete population of mesenchymal cells that wraps around vessels, variously called mural cells, perivascular cells or pericytes, as a major source for profibrotic stromal cells generating scar tissue. - Previously known for their vascular protective functions, increasing evidence suggests new and unexpected roles for these cells also in inflammation, repair/regeneration, and cancer. These new findings raise a number of challenging questions relative - to their functional diversity, as well as mechanisms of activation/ regulation in disease. The identification and specific targeting of functional subsets of mesenchymal perivascular cells may have notable impact in research and medicine, paving the - way for new therapeutic avenues in inflammatory/fibrotic diseases and cancer. - - 2020-10-31, ongoing project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - France - - - PERIF - - - ERC-2014-CoG - - - 648428 - - - - - UNIVERSITA DEGLI STUDI DI PAVIA - UNIVERSITA DEGLI STUDI DI PAVIA - INSTITUT PASTEUR - - - EUR 1 686 875 - - - Population genomics of co-evolution between non-retroviral RNA viruses and their hosts - - - EUR 1 686 875 - - - Italy - Italy - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - Recent discoveries clearly show that non-retroviral RNA viruses, despite not coding for reverse transcriptase and integrase, can transfer genetic material to their hosts, similarly to DNA viruses and retroviruses. The - distribution of non-retroviral integrated RNA viruses (NIRVs) in host populations, mechanisms of NIRVs formation and effects on hosts are unclear. The main objective of this proposal is to uncover the complex biological interactions between - non-retroviral RNA viruses and their hosts using the model system “Aedes albopictus and Flavivirus”. This system is ideal because Ae. albopictus is a known vector of non-retroviral RNA viruses, including several highly relevant for public health such - as dengue viruses (Flaviviridae, Flavivirus) and NIRVs phylogenetically related to Flaviviruses have been identified in its genome. First, a population genomic approach will be used to interrogate the genome of Ae. albopictus from different - geographic populations at their DNA and RNA levels. This approach will permit the systematic characterization of the distributions of NIRVs in natural host populations, the analyses of correlations between the presence of NIRVs and viral infections - and the description of NIRVs genomic context, from which insights on mechanisms of NIRVs formation can be derived. Secondly, tissue-specificity of the NIRVs, their trans-generational stability and impact on mosquito biology will be analysed in a - controlled laboratory environment. Somatic integrations could contribute to acquired immunity to their respective viruses or establishment of persistent viral infection. Germ-line integrations could have an evolutionary impact. If NIRVs affect Ae. - albopictus vector competence or the genome of emerging viral populations, they could be manipulated for vector control purposes. Additionally, results on NIRV distribution in natural host populations and mechanisms of NIRVs formation will have - implications in medicine because several non-retroviral RNA viruses are emerging as delivery systems for gene therapy applications. - - 2021-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Italy - - - NIRV_HOST_INT - - - ERC-2015-CoG - - - 682394 - - - - - INSTITUT PASTEUR - INSTITUT PASTEUR - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 499 726 - - - Reconstituting Autophagosome Biogenesis in vitro - - - EUR 1 499 726 - - - France - France - Germany - - - Research Organisations - Research Organisations - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Autophagy is a catabolic pathway that delivers cytoplasmic material to lysosomes for degradation. Under vegetative conditions, the pathway serves as quality control system, specifically targeting damaged or superfluous - organelles and protein-aggregates. Cytotoxic stresses and starvation, however, induces the formation of larger autophagosomes that capture cargo unselectively. Autophagosomes are being generated from a cup-shaped precursor membrane, the isolation - membrane, which expands to engulf cytoplasmic components. Sealing of this structure gives rise to the double-membrane surrounded autophagosomes. Two interconnected ubiquitin (Ub)-like conjugation systems coordinate the expansion of autophagosomes by - conjugating the autophagy related (Atg)-protein Atg8 to the isolation membrane. In an effort to unravel the function of Atg8, we reconstituted the system on model membranes in vitro and found that Atg8 forms together with the Atg12–Atg5-Atg16 complex - a membrane scaffold which is required for productive autophagy in yeast. Humans possess seven Atg8-homologs and two mutually exclusive Atg16-variants. Here, we propose to investigate the function of the human Ub-like conjugation system using a fully - reconstituted in vitro system. The spatiotemporal organization of recombinant fluorescent-labeled proteins with synthetic model membranes will be investigated using confocal and TIRF-microscopy. Structural information will be obtained by atomic force - and electron microscopy. Mechanistic insights, obtained from the in vitro work, will be tested in vivo in cultured human cells. We belief that revealing 1) the function of the human Ub-like conjugation system in autophagy, 2) the functional - differences of Atg8-homologs and the two Atg16-variants Atg16L1 and TECPR1 and 3) how Atg16L1 coordinates non-canonical autophagy will provide essential insights into the pathophysiology of cancer, neurodegenerative, and autoimmune diseases. - - 2020-03-31, ongoing project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - Autophagy in vitro - - - ERC-2014-STG - - - 638603 - - - - - INSTITUT PASTEUR - - - EUR 173 076 - - - Characterization of zebrafish innate lymphoid cells and IL-22 - - - EUR 173 076 - - - France - - - Research Organisations - - The immune system can be subdivided into two main arms: the innate and the adaptive. Recently, it was identified a new family of cells belonging to the innate system but that phenotypically and functionally resemble the - specific subtypes of adaptive T lymphocytes. In mice and in humans, these innate lymphoid cells (ILCs) play critical roles in host defense, in shaping the microbiota and in tissue repair at mucosal tissues via secreting cytokines such as IL-22. The - innate system is more ancient than the adaptive, however, the existence and diversity of ILCs in organisms other than mammals remains unknown. Also unknown is how ILCs interact with other cells within tissues. This project will address the existence - and role of the different subsets of ILCs and the conservation of IL-22 function in a distant relative, the zebrafish, a genetically tractable vertebrate with remarkable optical accessibility. - - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - ZF-ILC - - - H2020-MSCA-IF-2015 - - - 708128 - - - - - INSTITUT PASTEUR - INSTITUT PASTEUR - - - EUR 1 500 000 - - - Regulation of cell size and shape in bacteria - - - EUR 1 500 000 - - - France - France - - - Research Organisations - Research Organisations - - Proper cell size and shape are important for many biological functions, such as metabolism, signaling, motility, and development. This proposal addresses the fundamental question of how bacteria control their morphology and - their cell volume with high precision, using the rod-like bacterium Escherichia coli as a primary model system. Bacterial cell shape is physically determined during growth by the enzymatic expansion and remodeling of the peptidoglycan (PG) cell wall, - a partially ordered elastic meshwork that is the pressure-bearing component of the cell envelope. In this proposal we will address two fundamental questions: - - - 2021-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - RCSB - - - ERC-2015-STG - - - 679980 - - - - - INSTITUT PASTEUR - INSTITUT PASTEUR - - - EUR 1 499 763 - - - Study of the interplay between CRISPR interference and DNA repair pathways towards the development of novel CRISPR tools - - - EUR 1 499 763 - - - France - France - - - Research Organisations - Research Organisations - - CRISPR-Cas loci are the adaptive immune system of archaea and bacteria. They can capture pieces of invading DNA and use this information to degrade target DNA through the action of RNA-guided nucleases. The consequences of DNA - cleavage by Cas nucleases, i.e. how breaks are processed and whether they can be repaired, remains to be investigated. A better understanding of the interplay between DNA repair and CRISPR-Cas is critical both to shed light on the evolution and - biology of these fascinating systems and for the development of biotechnological tools based on Cas nucleases. CRISPR systems have indeed become a popular tool to edit Eukaryotic genomes. The strategies employed take advantage of different DNA repair - pathways to introduce mutations upon DNA cleavage. In bacteria however, the introduction of breaks by Cas nucleases in the chromosome has been described to kill the cell. Preliminary data indicates that this might not always be the case and that some - DNA repair pathways could compete with CRISPR immunity allowing cells to survive. Using a combination of bioinformatics and genetics approaches we will investigate the interplay between CRISPR and DNA repair in bacteria with a particular focus on the - widely used CRISPR-Cas9 system. The knowledge gained from this study will then help us develop novel tools for bacterial genome engineering. In particular we will introduce a NHEJ pathway in E.coli making it possible to perform CRISPR knockout - screens. Finally using CRISPR libraries and multiplexed targeting, we will generate for the first time all combinations of pair-wise gene knockouts in an organism, a task that for now remains elusive, even for large consortiums and with the use of - automation. This will enable to decipher genome-scale genetic interaction networks, an important step for our understanding of bacteria as a system. - - 2021-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - CRISPAIR - - - ERC-2015-STG - - - 677823 - - - - - INSTITUT PASTEUR - - - EUR 173 076 - - - Genetics of Alternative Transcript Abundance upon immune Cellular Activation - - - EUR 173 076 - - - France - - - Research Organisations - - The human body is constantly exposed to infectious agents. Efficient immune response is therefore fundamental to protect the cells from infection and keep individuals healthy. Still, extreme variations are observed in the - efficiency of immune response among individuals and populations. Recently, the dissection of the genetic bases of the host immune response to infection has fostered a large interest in the scientific community. As a result, there is now a growing - understanding of the influence of genetic variation on the transcriptional reprogramming of immune cells during infection. However, it is now widely accepted that the underlying ‘one gene–one protein’ paradigm is overly simplistic and cannot account - for the full complexity of the transcriptome. Here, we propose to study how genetic variants affect transcript diversity to modulate the response to pathogens at the individual and population levels. To do so, we will seek to identify genetic - variants that have conferred a selective advantage to human populations through modulation of isoforms usage in response to infection. This work will rely on an innovative strategy that combines coexpression-based studies of the isoform regulatory - networks with analysis of the genetic determinants of splicing in response to infection. In doing so, this study should improve our understanding of isoform regulation and identify novel regulatory elements and splicing factor-target relationships in - the specific context of infection. - - 2017-09-30, closed project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - GATTACA - - - H2020-MSCA-IF-2014 - - - 655417 - - - - - INSTITUT PASTEUR - INSTITUT PASTEUR - - - EUR 2 750 000 - - - Microbial invasion and dissemination within the host, mechanisms and effects - - - EUR 2 750 000 - - - France - France - - - Research Organisations - Research Organisations - - An infection is defined by the deleterious consequences of the interactions between a pathogen and a host. Thus, studying the biology of infection reveals critical properties of hosts and pathogens, and is a way forward to - address basic biological questions and improve health. - - 2021-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - France - - - INVADIS - - - ERC-2015-CoG - - - 681829 - - - - - INSTITUT PASTEUR - INSTITUT PASTEUR - - - EUR 1 498 955 - - - New and mature neurons in adult circuits: telling memories apart - - - EUR 1 498 955 - - - France - France - - - Research Organisations - Research Organisations - - How does the brain distinguish between memories that closely resemble each other? The hippocampal dentate gyrus has been suggested to serve this purpose by generating non-overlapping memory representations in a process termed - “pattern separation”. Intriguingly, during adult life, the dentate gyrus is constantly supplied with new neurons, providing new circuit elements that can incorporate into the neuronal network. How the activity of new adult-born neurons and mature - granule cells combines to drive the production and storage of distinct memories represents a new frontier in understanding brain function. However, to determine how these neurons transform similar synaptic input patterns into decorrelated spike - output patterns representing distinct memories, we need to monitor and manipulate their subthreshold and suprathreshold activity during behaviour. - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - NEWRON - - - ERC-2015-STG - - - 678790 - - - - - INSTITUT PASTEUR - INSTITUT PASTEUR - - - EUR 2 000 000 - - - Common mechanisms of host membrane trafficking subversion by intracellular pathogens to rupture bacterial containing vacuoles - - - EUR 2 000 000 - - - France - France - - - Research Organisations - Research Organisations - - A common strategy of bacterial pathogens is active or passive uptake into host cells. There, they can localize within a bacterial containing vacuole (BCV) or access the host cytoplasm through BCV rupture. Hence, intracellular - pathogens are often classified as vacuole-bound or cytoplasmic. Recently, this definition has been challenged by the discovery that many vacuole-bound pathogens, including Mycobacterium tuberculosis and Salmonella enterica, access the host cytoplasm, - and by the insight that cytoplasmic bacteria, like Shigella flexneri or Listeria monocytogenes, do not always escape the BCV. Despite this increasing complexity, a precise understanding lacks for why and how a pathogen “chooses” between a BCV or the - cytoplasm and yet this is very important: because of differential pathogen sensing in membrane-bound and cytoplasmic compartments, intracellular localization leads to induction of different host responses. Therefore, a comprehensive understanding of - the processes controlling BCV integrity is not only essential, but can provide new therapeutic targets. Our previous research has implemented innovative fluorescence microscopy to track the invasion steps of pathogenic bacteria. We have further - integrated a large-volume, correlative, light/electron microscopy (CLEM) workflow via focused ion beam scanning electron microscopy. This uncovered the subversion of host Rab cascades by Shigella to rupture its BCV. Starting with the Shigella model - of epithelial cell invasion, we will delineate the precise molecular mechanisms controlling BCV integrity in different host cell types. We will analyze (i) the scaffolds of host pathways for membrane remodeling, (ii) their subversion by various - pathogens, and (iii) their differential regulation depending on pathophysiological conditions. Together, this will allow development of novel, rational antimicrobial strategies and will yield fundamental insight into understudied cell biological - mechanisms of membrane trafficking. - - 2021-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - France - - - EndoSubvert - - - ERC-2015-CoG - - - 682809 - - - - - INSTITUT PASTEUR - - - EUR 185 076 - - - Making a yeast-based candidate vaccine against Porcine Epidemic Diarrhea Virus (PEDV) - - - EUR 185 076 - - - France - - - Research Organisations - - PIGYVAX aims to create pig vaccine candidates against PEDV, a pathogen of swine causing significant challenges to the swine industry globally. This project will utilize yeast-based vaccine carrying nanoparticles of measles - ribonucleoprotein (RNP) fused with PEDV spike protein (S1). The multimerization of monomeric S1 antigen through RNP will increase immunogenicity due to better recognition of antigen presenting cells. As the yeast delivery system has strong - auto-adjuvant properties, the vaccine does not require complementation with accessory adjuvant, which reduces the cost of vaccine production. Moreover, P. pastoris yeast, commonly present on fruits, is a certified safe microorganism for animal feeds - rendering it a most practical and convenient way to deliver vaccines to large-scale farms. Therefore, we aim to use this vaccine platform to express S1 antigen of PEDV and deliver it orally to stimulate a protective immune response against PEDV in - sows, which will be passively transferred to fully protect piglets from succumbing to the disease. In this project, Dr. Phanramphoei Frantz will utilize her knowledge on pathogenesis of PEDV and the yeast-RNP platform while gaining expertise on - vaccine study and development from the host institute. This will initiate a successful collaboration project between Institut Pasteur and BIOTEC (Thailand) to where the experienced researcher will return after the project. - - 2018-06-12, ongoing project - - - 2016-06-13 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - PIGYVAX - - - H2020-MSCA-IF-2015 - - - 707128 - - - - - INSTITUT PASTEUR - INSTITUT PASTEUR - - - EUR 1 147 500 - - - Bacterial, cellular and epigenetic factors that control enteropathogenicity - - - EUR 1 147 500 - - - France - France - - - Research Organisations - Research Organisations - - Understanding the establishment and persistence of bacterial infections in the gut requires integrating an ensemble of factors including bacterial and host components and the presence of other microorganisms. We will - capitalize on 25 years of studies on the bacterium Listeria monocytogenes used as a model, to focus on three objectives which will significantly increase our knowledge of the bacterium, of the cell biology of infection and of the epigenetic - reprogramming upon infection. - - - 2018-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - France - - - BacCellEpi - - - ERC-2014-ADG - - - 670823 - - - - - INSTITUT PASTEUR - - - EUR 2 354 400 - - - Institut Pasteur International Docotal Program - - - EUR 4 708 800 - - - France - - - Research Organisations - - PASTEURDOC is an advanced educational and research program, hosted by the Institut Pasteur in Paris. Its goal is to train junior investigators possessing medical and/or scientific educational backgrounds to become future - leaders in academic education and research institutions, international organizations, private companies, or administration. PASTEURDOC is intended to co-fund and advance the already well-established and very successful Pasteur Paris University - International Doctoral Program, in operation since 2009 in partnership with three renowned Parisian universities. PASTEURDOC will enhance the host capacity to train young researchers, while strengthening the Marie Skłodowska-Curie Actions - recommendations for professional development of early-stage researchers. - - - 2020-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2014-DP - Marie Skłodowska-Curie Co-funding of regional, national and international programmes (COFUND-DP) - - - MSCA-COFUND-DP - Doctoral programmes - - - France - - - PASTEURDOC - - - H2020-MSCA-COFUND-2014 - - - 665807 - - - - - HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH - PHILIPPS UNIVERSITAET MARBURG - RIJKSUNIVERSITEIT GRONINGEN - UPPSALA UNIVERSITET - INSTITUT PASTEUR - UNIWERSYTET JAGIELLONSKI - Eidgenössische Technische Hochschule Zürich - Novartis Pharma AG - RIDGEVIEW INSTRUMENTS AB - ASTRAZENECA AB - GIOTTO BIOTECH - - - EUR 3 836 995,92 - - - Accelerated Early staGe drug diScovery - - - EUR 3 836 995,92 - - - Germany - Germany - Netherlands - Sweden - France - Poland - Switzerland - Switzerland - Sweden - Sweden - Italy - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The development of effective novel drugs - especially for rare and neglected diseases - is one of the biggest challenges of the upcoming decades, as illustrated by the recent Ebola outbreak. Moreover, European innovation in - new drug registrations is dramatically falling behind compared to the US and Asia. - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - AEGIS - - - H2020-MSCA-ITN-2015 - - - 675555 - - - - - UNIVERSITEIT UTRECHT - TECHNISCHE UNIVERSITAET DRESDEN - INSTITUT CURIE - THE FRANCIS CRICK INSTITUTE LIMITED - CARDIFF UNIVERSITY - UNIVERSITY COLLEGE LONDON - INSTITUT PASTEUR - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSITAET BASEL - - - EUR 3 935 968,56 - - - Principles of Polarity – Integrating genetic, biophysical and computational approaches to understand cell and tissue polarity - - - EUR 3 935 968,56 - - - Netherlands - Germany - France - United Kingdom - United Kingdom - United Kingdom - France - France - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - - The ability of cells to polarize underlies the most basic biological functions such as motility and response to external challenges, but also the formation and maintenance of tissues in a multicellular organism. The importance - of cell polarity is underscored by the fact that cell polarity is essential for animal development and is perturbed in disease states such as cancer. Understanding cell polarity requires knowledge of the molecular players involved and a quantitative - description of their biochemical interactions, as well as the mechanical processes underlying polarity establishment. PolarNet brings together academic and private partners from 7 European countries to establish a multidisciplinary, intersectoral - training and research programme that will study the basic principles of cell polarity. The research will combine complementary model systems ranging from fungi and cultured mammalian cells to whole organisms, and employ a broad set of approaches such - as advanced genetics, protein biochemistry, high-resolution live imaging and image analysis, biophysics and theoretical modelling. This setting provides an opportunity to train early stage researchers in a unique combination of experimental and - theoretical approaches. This will provide an excellent starting point for a successful career in the rapidly expanding field of multidisciplinary or ‘integrative’ biology. Training Europe’s next generation of scientists at the forefront of cell and - organismal polarity research is crucial for progress in several medically important fields, including cancer research and stem cell biology. The tight collaboration with non-academic partners will strengthen the technological base of different - projects and provide early stage researchers with insights into the translation potential of the performed studies and the career development opportunities in biomedical industry. - - 2019-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Netherlands - - - PolarNet - - - H2020-MSCA-ITN-2015 - - - 675407 - - - - - SKA ORGANISATION - NATIONAL RESEARCH FOUNDATION - COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION - - - EUR 4 955 475 - - - Square Kilometre Array: Infrastructure Detailed Design for SKA Phase 1 - - - EUR 4 955 475 - - - United Kingdom - South Africa - Australia - - - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - - The Square Kilometre Array (SKA) is an international project to construct the largest and most sensitive radio telescope ever conceived. The SKA will use hundreds of thousands of radio telescopes receivers, in three unique - configurations, which will enable astronomers to monitor the sky in unprecedented detail and survey the entire sky thousands of times faster than any system currently in existence. The SKA telescopes will be co-located in Africa and in Australia. - South Africa’s Karoo desert will cover the core of the high and mid frequencies of the radio spectrum which will have telescopes spread all over the continent, with Australia’s Murchison region covering the low frequency range and hosting the survey - instrument. The objective of the IN-SKA proposal is to support the implementation of the SKA, enabling the start of construction in 2018 and delivery of first science around 2020. To achieve this, the proposal plans to provide resources to complete - the Detailed Design of the core SKA Infrastructure required in South Africa and Australia. The proposed programme will address the design of roads and civil works, power distribution to run the telescope and supporting computing facilities, antenna - foundations and the specialist design of new buildings; buildings that will be suitable for maintaining a pristine radio-quiet environment needed to ensure that SKA is able to achieve its science goals. In addition to driving innovation in many - areas, and supporting the SKA as an inspirational vehicle for skills, industry and outreach, the ultimate deliverables of tender documentation ready for construction will place European and other national industry in leading positions to benefit - directly from implementation of the SKA in 2018. - - 2018-02-28, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-3-2015 - Individual implementation and operation of ESFRI projects - - - RIA - Research and Innovation action - - - United Kingdom - - - IN-SKA - - - H2020-INFRADEV-1-2015-1 - - - 676621 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA - KOBENHAVNS UNIVERSITET - UNIVERSITY COLLEGE LONDON - FORSCHUNGSVERBUND BERLIN EV - HELLENIC CENTRE FOR MARINE RESEARCH - ISPA CRL - - - EUR 3 950 859,24 - - - INternational training at the Science-Policy Interface for Researchers in Europe, for Nature - - - EUR 3 950 859,24 - - - France - Italy - Denmark - United Kingdom - Germany - Greece - Portugal - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - - The growing recognition that biological diversity is a global asset of tremendous value to present and future generations has underpinned a number of multilateral environmental policy agreements, including the EU Biodiversity - Strategy to 2020. Implementing these agreements requires a global-scale cooperation among conservation scientists to collect, mobilise and synthesise biodiversity data and ecological knowledge, and translating them directly into recommendations for - conservation action and indicators of progress towards meeting internationally agreed goals and targets. Inspire4Nature’s purpose is to contribute to the formation of a new generation of creative, entrepreneurial and innovative early-stage - researchers by providing them with both research-related and transferable skills which will enable them to work at this science-policy interface, converting their knowledge and ideas into tools for tackling complex global environmental problems. To - do so, we propose an ambitious training programme combining individual research projects (leading to PhD degrees) of a high scientific standard strategically positioned at the science-policy interface in biodiversity conservation with a rich - network-wide training programme including training events and joint projects that will provide the ESRs with a wide diversity of scientific, communication and project management skills. The Consortium’s strength comes from an unprecedented - collaboration between academic and non-academic conservation organisations that will generate in the European research area a unique focus of professional training at the interface between conservation science and policy. - - 2022-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - France - - - Inspire4Nature - - - H2020-MSCA-ITN-2017 - - - 766417 - - - - - ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA - TECHNISCHE UNIVERSITAET WIEN - UNIVERSITA DEGLI STUDI DI PERUGIA - THE UNIVERSITY OF NOTTINGHAM - UNIVERSIDAD DE CANTABRIA - INSTITUT FRANCAIS DES SCIENCES ET TECHNOLOGIES DES TRANSPORTS, DE L'AMENAGEMENT ET DES RESEAUX - COVENTRY UNIVERSITY - UNIVERSITY COLLEGE LONDON - LANCASTER UNIVERSITY - UNIVERSITAET INNSBRUCK - CELU EKSPERTS - DURTH ROOS CONSULTING GMBH - SOCIETA' AZIONARIA PRODOTTI ASFALTICO BITUMINOSI AFFINI - S.A.P.A.B.A. S.P.A. - - - EUR 3 878 868,96 - - - Sustainable, Accessible, Safe, Resilient and Smart Urban Pavements - - - EUR 3 878 868,96 - - - Italy - Austria - Italy - United Kingdom - Spain - France - United Kingdom - United Kingdom - United Kingdom - Austria - Latvia - Germany - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Urban pavements comprise almost 40% of European cities and are the main means by which people travel every day. Urban pavements must accommodate all users in the most efficient, safe, sustainable and smart way. A key factor to - increase the liveability of tomorrow’s Smart cities will be transforming the way urban pavements are perceived, designed, built, maintained and function. SAFERUP! aims to provide cities with innovative solutions that will form the future urban paved - environment, by training talented researchers in the fields of: smart, recycled and durable paving materials; provision for vulnerable users (e.g. elderly & disabled) accessibility and protection; studying user behaviour; life cycle analysis; - wash-off water management and bioremediation; tempered and acoustic pavements; energy harvesting and self-sensing technologies. The SAFERUP! Consortium believes in this future and has created a unique team of world leading commercial and academic - research engineers and scientists, with the diverse range of expertise needed to develop the novel solutions required to deliver this future and its anticipated benefits. Fifteen ESRs will undertake their PhDs in a research and training programme - designed to optimise their multidisciplinary and cross-sectoral experience through secondments and a variety of SAFERUP!-wide fora. All ESRs’ projects are interrelated and considerable synergies, trans-project contributions and collaborations will - occur. A key focus of the training will be career planning, entrepreneurship and skills development in particular communication. SAFERUP! participants with communication expertise will develop the communication and dissemination strategy to maximise - the exploitation of the developed solutions. SAFERUP! will create a new generation of professionals with multidisciplinary expertise in urban pavements and allied fields appealing to employers, who will expand the social benefits of the new urban - pavements well beyond the end of SAFERUP! - - 2022-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Italy - - - SAFERUP - - - H2020-MSCA-ITN-2017 - - - 765057 - - - - - KOBENHAVNS UNIVERSITET - SAROMICS BIOSTRUCTURES AB - ENAMINE LIMITED LIABILITY COMPANY,RESEARCH AND PRODUCTION ENTERPRISE - - - EUR 1 286 630,94 - - - Selective Agonists For Serotonin Receptors - - - EUR 1 286 630,94 - - - Denmark - Sweden - Ukraine - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - SAFER will train 5 ESRs, PhD students, to obtain ample scientific, business and transferrable skills, arming them with the expertise to translate knowledge into products and services with importance for European industry and - society. All ESRs will first train together at one university to develop complementary skills and basic research data; and subsequently move to two SMEs for applied and commercial research. - - - 2021-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-EID - European Industrial Doctorates - - - Denmark - - - SAFER - - - H2020-MSCA-ITN-2017 - - - 765657 - - - - - THE UNIVERSITY OF NOTTINGHAM - HELSINGIN YLIOPISTO - NIZO FOOD RESEARCH BV - UNIVERSIDADE NOVA DE LISBOA - INSTITUTO DE TECNOLOGIA QUIMICA E BIOLOGICA - UNIVERSIDADE NOVA DE LISBOA - PURAC BIOCHEM BV - INSTITUT PASTEUR - Green Biologics Ltd. - STICHTING WAGENINGEN RESEARCH - - - EUR 3 910 777,56 - - - UNDERSTANDING THE CLOSTRIDIUM SPORE, A PREREQUISTE FOR DISEASE INTERVENTIONS AND EXPLOITATION - - - EUR 3 910 777,56 - - - United Kingdom - Finland - Netherlands - Portugal - Portugal - Netherlands - France - United Kingdom - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - - Bacterial endospores are the most resistant life-forms on earth and the most important single feature of the genus Clostridium. Thus, whilst the pathogenesis of its notorious pathogens (C. botulinum, C. perfringens and C. - difficile) is ascribed to the devastating toxins produced (neurotoxins, endotoxins and cytotoxins), it is their capacity to produce spores that lies at the heart of the diseases they cause. This is because spores play the pivotal role in the spread - of infection (eg, C. difficile) and in foodstuff contamination and food poisoning (eg, C. botulinum and C. perfringens). The processes of spore formation (sporulation) and germination (return of the dormant spore to toxin-producing, vegetative - cells), therefore, represent key intervention points. On the other hand, the majority of clostridia are entirely benign and can sustainably produce all manner of useful chemicals and fuels. Crucially, the regulation of chemical production is - intimately linked to that of sporulation. Spores of benign species may also be used as a delivery system for treating cancer. Yet, despite the spore’s importance, little is known of the developmental processes of sporulation and germination. This is - because research and training efforts on Clostridium spores are fragmented and there is no coherence between researchers working on pathogenic and industrially important species. CLOSPORE will address this deficiency by pooling the resources of - Europe’s leading universities, research organisations and companies, to create an intersectorial Research and Training Programme that is multi-facetted, interdisciplinary and focused on clostridial spores. Accordingly, CLOSPORE will produce the - innovative, applied research leaders of the future, able to tackle the big societal challenges facing Europe and the world. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - CLOSPORE - - - H2020-MSCA-ITN-2014 - - - 642068 - - - - - UNIVERSITY COLLEGE LONDON - UNIVERZITA KARLOVA - UNIWERSYTET JAGIELLONSKI - BUDAPESTI CORVINUS EGYETEM - TARTU ULIKOOL - UNIVERZITET U BEOGRADU - - - EUR 3 508 841,16 - - - Delayed Transformational Fatigue in Central and Eastern Europe - - - EUR 3 508 841,16 - - - United Kingdom - Czech Republic - Poland - Hungary - Estonia - Serbia - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The aim of FATIGUE is to develop theoretically and empirically robust explanations for the causes and consequences of rise of illiberalism and authoritarianism in post-communist Europe (and Europe, more generally) with - reference to the concept of 'delayed transformational fatigue'. The project will seek to answer the following questions: - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - FATIGUE - - - H2020-MSCA-ITN-2017 - - - 765224 - - - - - KATHOLIEKE UNIVERSITEIT LEUVEN - KOBENHAVNS UNIVERSITET - INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE - DOHLER GMBH - CARGILL R&D CENTRE EUROPE - - - EUR 3 437 311,68 - - - Enginomics in food quality design: the case of shelf-stable fruit-, vegetable- and legume-based foods - - - EUR 3 437 311,68 - - - Belgium - Denmark - France - Germany - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The overarching objective of FOODENGINE is to provide, for the first time, a research-based training programme to a new generation of young food scientists and technologists by introducing an enginomics approach in food - quality design. It connects an omics approach to instrumentally quantify food quality with an advanced engineering approach using multi-response kinetics to model food quality changes during processing and storage. At the same time, FOODENGINE will - develop models linking the enginomics-based instrumental food quality design with sensory properties, consumer acceptability and consumer preferences to create new products appealing to consumers. FOODENGINE provides unique interdisciplinary, - international and intersectoral training opportunities to 13 ESRs, each for 36 months. This extensive international (5 countries), intersectoral (2 universities, 1 research institute and 6 food (ingredient) companies) and interdisciplinary (food - engineering, food chemistry, food nutrition and sensory/consumer research) training should lead for all ESRs to a PhD degree. FOODENGINE will boost the career perspectives of the FOODENGINE fellows to the top level. In addition, it has the ambition - to become a best-practise example for structuring PhD research training in food science and technology at the European level. Although FOODENGINE specifically focusses on sustainable commodities which are essential parts of a healthy lifestyle - (fruit-, vegetable-, legume-based food ingredients and foods), the skills and new ways of thinking the fellows will acquire are generic and can be extrapolated beyond the specific application area (diverse range of food systems or food processes) in - their future careers. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Belgium - - - FOODENGINE - - - H2020-MSCA-ITN-2017 - - - 765415 - - - - - STICHTING VUMC - OTICON A/S - THE UNIVERSITY OF NOTTINGHAM - - - EUR 1 637 488,08 - - - HEAR-ECO Innovative Hearing Aid Research - Ecological Conditions and Outcome Measures - - - EUR 1 637 488,08 - - - Netherlands - Denmark - United Kingdom - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - In today’s ageing European population, hearing impairment is an increasing concern for public health and societal participation. The percentage of hearing-impaired people will rise from around 16% of the adult EU population - now to around 40% in 2030. Hearing aid (HA) fitting is the most widely prescribed solution for hearing impairment. However, only around 30%-40% of adults with hearing impairment use HAs in daily life. One of the reasons for this is that methods used - to develop and evaluate HAs are still not based on conditions in which HAs are actually used. Thus the potential of improved HA technology to meet the needs of individual users in their daily lives is acutely under-exploited. The science in HEAR-ECO - will help to facilitate the paradigm shift which is needed to bridge the gap. Such a paradigm shift requires a new generation of hearing scientists that are able to integrate conventional Audiology with Motivational and Social psychology (motivation - to listen, cognition), Psychophysiology (pupillometry, PEP, EEG), and HA technology. HEAR-ECO will train six ESRs capable of spanning these disciplines and translating their knowledge into innovative technological HA evaluation and development. The - six ESRs will be trained through local training at academic partners in The Netherlands and the UK and secondment to one of the largest hearing aid manufacturers in the world in Denmark – and through network wide training, including an associated - partner in Liverpool. The ESRs will be capable of developing and combining new tools and outcome measures for realistic everyday communication and translating this to innovative technological HA evaluation and development. - - 2021-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-EID - European Industrial Doctorates - - - Netherlands - - - HEAR-ECO - - - H2020-MSCA-ITN-2017 - - - 765329 - - - - - NOFIMA AS - UNIVERSITA DEGLI STUDI DI FIRENZE - WAGENINGEN UNIVERSITY - INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE - AARHUS UNIVERSITET - CENTRE DE RECHERCHE DE L INSTITUT PAUL BOCUSE - UNIVERSIDAD DE LA REPUBLICA - - - EUR 2 933 056,80 - - - BRINGING DOWN BARRIERS TO CHILDREN’S HEALTHY EATING - - - EUR 2 933 056,80 - - - Norway - Italy - Netherlands - France - Denmark - France - Uruguay - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - Edulia responds to the urgent need of EU society to find new ways to tackle the escalating issue of obesity, through promoting healthier eating from childhood. Based on the relations of sensory perception, pleasure, food - choice and food behaviour, the project will look for new approaches to drive children to like and actively choose healthy foods, developing healthier habits. Edulia is a multi-disciplinary and inter-sectorial European Training and Research Network - with a global reach. Our network will train a new generation of innovative and adaptable researchers, with highly specialised skills across complementary fields studying children’s food choice, while exposing them to cross-sector experiences, in - order to build strong career development paths. The training program includes multidisciplinary scientific training within natural and social sciences, secondments in academic and non-academic organisations, and courses in transferable skills, - promoting science communication and outreach. The overall aim of the research programme is to better understand how multiple factors act as barriers for children’s healthy eating and how to tackle them, bringing together leading scientists in the - Food Choice arena in a collaborative network that will transcend the limits of this project and strengthen European research. Edulia will go further than the classical approach of “teaching children what is healthy”, by exploring approaches such as - positive marketing, nudging strategies, focusing on peer and family social interactions, studying sensory and non-sensory parameters that influence what is eaten (food choice) and how much is eaten (intake), and exploiting the positive food sensory - characteristics which can drive healthy eating through enhancing pleasure. We will ultimately propose innovative approaches to support children’s healthier eating, providing a strong knowledge base and clear guidance for children, the general public, - the food industry and EU policy makers. - - 2022-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Norway - - - Edulia - - - H2020-MSCA-ITN-2017 - - - 764985 - - - - - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH - Bruker HTS GmbH - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - CONSIGLIO NAZIONALE DELLE RICERCHE - Columbus Superconductors SpA - HELMHOLTZ-ZENTRUM BERLIN FUR MATERIALIEN UND ENERGIE GMBH - I-CUBE RESEARCH - ISTITUTO NAZIONALE DI FISICA NUCLEARE - TECHNISCHE UNIVERSITAET DRESDEN - TECHNISCHE UNIVERSITAET WIEN - UNIVERSITAET SIEGEN - UNIVERSITAET STUTTGART - WIRTSCHAFTSUNIVERSITAT WIEN - - - EUR 3 841 922,16 - - - European Advanced Superconductivity Innovation and Training - - - EUR 3 841 922,16 - - - Switzerland - Germany - France - Italy - Italy - Germany - France - Italy - Germany - Austria - Germany - Germany - Austria - - - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The two greatest obstacles to a wide spread adoption of superconductivity remain the limited understanding of its fundamental principles and the yet insufficient capability for large-scale, cost-effective deployment of the - technology. Science rather than serendipity is the key to unlock the potentials of this alluring natural phenomenon. The proposed ITN integrates sound research projects aimed at learning to predict the behaviour of superconducting materials, at - introducing innovative manufacturing techniques, at developing efficient cryogenic refrigeration techniques as key enablers for future applications and establishing these technologies as the new state of the art. The ambitious goals of this - consortium are (1) making advanced superconductors fitter for the market, (2) assessing their innovation capacities and (3) equipping a new generation of researchers with the unique skills required to convert knowledge into products: Efficient grid - power management, 21st century medical imaging, leaps in effectiveness of wind power generators, efficient electric propulsion systems and sustainable refrigeration for industry give an impression of the potential societal benefits that - superconductor-based technologies can catalyze. This initiative under European leadership federates leading universities, research centres and industries, embracing a variety of science sectors, such as physics and mathematics, material sciences, - process and mechanical engineering, refrigeration, cryogenics and innovation management. The intriguing blend of science and engineering, compounded by visionary application opportunities in companies, creates a fertile environment for innovative - training of early-stage researchers. Significant training lead-times call for a dedicated action. This ITN will provide its fellows with a sound knowledge in the relevant fields along with business competences and prepare them for a broad spectrum of - career opportunities in research and industry. - - 2021-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Switzerland - - - EASITrain - - - H2020-MSCA-ITN-2017 - - - 764879 - - - - - UNIVERSITE CATHOLIQUE DE LOUVAIN - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - DSM Ahead BV - UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II. - DANMARKS TEKNISKE UNIVERSITET - JOHANNES GUTENBERG-UNIVERSITAT MAINZ - ECOLE SUPERIEURE DE PHYSIQUE ET DECHIMIE INDUSTRIELLES DE LA VILLE DEPARIS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 3 340 690,20 - - - Double Dynamics for design of new responsive polymer networks and gels - - - EUR 3 340 690,20 - - - Belgium - Greece - Netherlands - Italy - Denmark - Germany - France - France - - - Higher or Secondary Education Establishments - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - Polymeric gels and networks are ubiquitous in daily life (foodstuff, cosmetics) and high-added value applications (tissue engineering, adhesives, coating, drug release, portable batteries, additive manufacturing). They can be - either permanent (covalently crosslinked) and resist flow, or physical (reversible) and easy to process while creeping at long times. The grand challenge is to efficiently combine and control within the same material, distinct features of these two - classes of networks, such as large mechanical strength, deformability, swelling and self-healing, in order to create multiply responsive materials for new applications. - - 2021-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Belgium - - - DoDyNet - - - H2020-MSCA-ITN-2017 - - - 765811 - - - - - RIJKSUNIVERSITEIT GRONINGEN - AALBORG UNIVERSITET - THE UNIVERSITY OF EDINBURGH - EUROPA-UNIVERSITAT FLENSBURG - UNIVERSITETET I STAVANGER - CHALMERS TEKNISKA HOEGSKOLA AB - - - EUR 4 067 521,56 - - - Energy Systems in Transition - - - EUR 4 067 521,56 - - - Netherlands - Denmark - United Kingdom - Germany - Norway - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - To facilitate the necessary energy transition, there is an urgent need for highly trained professionals with the scientific knowledge and professional skills to analyse, understand and design relevant (new) energy systems and - governance in different sectors and administration. The proposed project Energy Systems in Transition (ENSYSTRA) aims to train 15 ESRs in this field. The objectives of ENSYSTRA are 1) to develop state-of-the-art science of energy systems transition, - scenario analysis and energy modelling tools with emphasis on interdisciplinary model collaboration, 2) to provide ESRs with interdisciplinary, inter-sectoral and applied perspectives on the energy transition, 3) to provide new skills and competences - for interdisciplinary analysis, 3) to establish collaboration between key universities and their networks, 4) to create and increase linkages between different academic disciplines, applied research, industry and the public sector, 5) develop links - and synergies between relevant scientific arenas, and 6) to contribute to accessible energy science based on open source work environments. By focussing on a prominent ‘’living lab’’ of the energy transition, the North Sea region, the project will - bring together a strong network and analytical capacity to understand energy system & scenario modeling; new energy technologies & infrastructures; actor behavior & interactions; and policy & market design, linking the regional to the - international scale. Through a carefully designed training programme, ESRs are trained in both scientific and transferable skills with ample opportunity to collaborate between different projects and partners. The total effort will result in major - progress in the field of energy system analysis and transition modelling. By the combined use and improvement of a range of modelling tools and methods, the project will deliver integral insights in energy transition pathways, policy implications and - options for the North Sea region. - - 2021-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Netherlands - - - ENSYSTRA - - - H2020-MSCA-ITN-2017 - - - 765515 - - - - - UNIVERSITE DE LIMOGES - AKADEMIA GORNICZO-HUTNICZA IM. STANISLAWA STASZICA W KRAKOWIE - RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN - MONTANUNIVERSITAT LEOBEN - UNIVERSITE D'ORLEANS - UNIVERSIDADE DO MINHO - - - EUR 3 737 239,56 - - - Advanced THermomechanical mOdelling of Refractory linings - - - EUR 3 737 239,56 - - - France - Poland - Germany - Austria - France - Portugal - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Refractories are heat-resistant materials used as inner linings of high temperature furnaces, reactors and processing units. ATHOR (Advanced THermomechanical multiscale mOdelling of Refractory linings) is an innovative, - collaborative and interdisciplinary project that brings together 6 academic beneficiaries and 8 private partners. The main objective is to develop high-end engineering technologies in material engineering and numerical simulations thanks to an - intensive cooperation between academia, raw materials suppliers, refractory producers and end-users. Starting from material characterization, all significant properties will be investigated, including fracture behaviour, tension and compression creep - behaviour, corrosion and thermal shock resistance. The interdisciplinary aspects will be addressed thanks to a multiscale approach looking at the influences of micro-, meso- and macro-characteristics on each other. To conduct their research and - interlink the different topics, the 15 recruited researchers will take advantage of the most sophisticated numerical tools to model, design and predict the life of different lining configurations in critical operation conditions. - - 2021-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - France - - - ATHOR - - - H2020-MSCA-ITN-2017 - - - 764987 - - - - - INSTITUT PASTEUR - - - EUR 173 076 - - - Metabolic characterization of ILCs under homeostatic or stress conditions. - - - EUR 173 076 - - - France - - - Research Organisations - - Innate lymphoid cells (ILCs) are the most recently identified components of the innate immune system. ILCs colonize mainly mucosa-associated tissues and they have a crucial role in metabolic homeostasis, and defense against - infections and cancer. ILCs are highly plastic and they rapidly shape their functional output in response to local environmental cues. Two ILC subsets (ILC2 and NK cells) have been respectively implicated in the maintenance of adipose tissue - homeostasis and in the development of chronic inflammation in obese patients. It has been shown that cellular metabolism affects the development and function of adaptive lymphocytes. In contrast, very little is known about innate lymphocytes - metabolic requirements under homeostatic conditions and how they metabolically adapt to environmental perturbations. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - ILMET - - - H2020-MSCA-IF-2016 - - - 746828 - - - - - INSTITUT PASTEUR - - - EUR 185 076 - - - Uncovering the role of cis genetic elements in antigenic variation of Plasmodium falciparum using the CRISPR-Cas9 genome editing technology - - - EUR 185 076 - - - France - - - Research Organisations - - Malaria is an infectious human disease caused by parasitic protozoans of the Plasmodium type. P. falciparum causes the most lethal form with about 400.000 deaths annually. Pathogenesis involves expression of clonally variant - molecules encoded by multi gene families at the surface of the infected host cells (erythrocyte). The most important virulence factor is called PfEMP1, which undergoes antigenic variation and is encoded by 60 var gene members. Despite the major - scientific efforts, the molecular mechanisms orchestrating antigenic variation are still elusive. The reason is the lack of tools to perform genome editing in the natural epigenetic context, which is crucial in this important immune escape process. - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - REACT - - - H2020-MSCA-IF-2016 - - - 741447 - - - - - INSTITUT PASTEUR - BACMINE SL - SWANSEA UNIVERSITY - - - EUR 900 000 - - - SustainAble Farming for Effective Aquaculture - - - EUR 900 000 - - - France - Spain - United Kingdom - - - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - Aquaculture is an important food source for the world’s growing population. The increasing demand and productivity of aquaculture leads to global trade in breeding stock, genetic material and aquaculture products for human - consumption, but also exacerbates the globalization of pathogens.SAFE-Aqua, an international inter- and multidisciplinary consortium, aims to provide scientific solutions to solve disease-related issues in aquaculture using shrimp as a model through - research and innovation staff exchange and sharing of knowledge and ideas from research to market. SAFE-Aqua will explore the benefits of developed feed additives on keeping a healthy gut microbial balance, enhancing immune-capacity, and maintaining - nutritional integrity of shrimp as a product. To assess these beneficial effects, SAFE-Aqua will synergize the cutting-edge technology platforms, multidisciplinary and complementary expertise, as well as infrastructure from networks of the - partnership among the leading research institutes in France, UK and Thailand and a synthetic biology company in Spain. - - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - France - - - SAFE-Aqua - - - H2020-MSCA-RISE-2016 - - - 734486 - - - - - INFRAFRONTIER GMBH - HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH - USTAV MOLEKULARNI GENETIKY AKADEMIE VED CESKE REPUBLIKY VEREJNA VYZKUMNA INSTITUCE - OULUN YLIOPISTO - CENTRE EUROPEEN DE RECHERCHE EN BIOLOGIE ET MEDECINE - BIOMEDICAL SCIENCES RESEARCH CENTER ALEXANDER FLEMING - VETERINAERMEDIZINISCHE UNIVERSITAET WIEN - Toronto Centre for Phenogenomics Inc. - EUROPEAN MOLECULAR BIOLOGY LABORATORY - HELMHOLTZ-ZENTRUM FUER INFEKTIONSFORSCHUNG GMBH - MEDIZINISCHE HOCHSCHULE HANNOVER - TSE SYSTEMS GMBH - AYOXXA BIOSYSTEMS GMBH - KOBENHAVNS UNIVERSITET - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - UNIVERSITAT AUTONOMA DE BARCELONA - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - INSTITUT PASTEUR - Biomedcode Hellas SA - TEL AVIV UNIVERSITY - CONSIGLIO NAZIONALE DELLE RICERCHE - STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS - ACADEMISCH ZIEKENHUIS GRONINGEN - FUNDACAO CALOUSTE GULBENKIAN - KAROLINSKA INSTITUTET - MEDICAL RESEARCH COUNCIL - GENOME RESEARCH LIMITED - THE UNIVERSITY OF SHEFFIELD - - - EUR 4 955 877,16 - - - Towards enduring mouse resources and services advancing research into human health and disease - - - EUR 4 968 252,16 - - - Germany - Germany - Czech Republic - Finland - France - Greece - Austria - Canada - Germany - Germany - Germany - Germany - Germany - Denmark - Spain - Spain - France - France - France - Greece - Israel - Italy - Netherlands - Netherlands - Portugal - Sweden - United Kingdom - United Kingdom - United Kingdom - - - Other - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - - The INFRAFRONTIER RI integrates European Mouse Clinics and the European Mouse Mutant Archive with the common goal to ensure access to mouse models for basic research of human health and disease, and to translate this knowledge - into therapeutic approaches for the benefit of the European society. - - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-03-2016-2017 - Individual support to ESFRI and other world-class research infrastructures - - - CSA - Coordination and support action - - - Germany - - - INFRAFRONTIER2020 - - - H2020-INFRADEV-2016-1 - - - 730879 - - - - - INSTITUT PASTEUR - INSTITUT PASTEUR - - - EUR 1 675 746 - - - Development, maintenance and functions of Resident Macrophages. - - - EUR 1 675 746 - - - France - France - - - Research Organisations - Research Organisations - - Macrophages are professional phagocytic cells that orchestrate homeostatic and innate immune functions, via the scavenging of cells, debris, and pathogens, and the production of cytokines, both concurring to tissue homeostasis - and repair. This project aims to investigate in vivo the development and functions of macrophages, which have considerable phenotypic and functional diversity depending on their tissue of residence and pathophysiological conditions. Because this - diversity is not well understood, the functions of macrophages in vivo have not been well characterized. Most hematopoietic cells renew from hematopoietic stem cells (HSC), however recent evidence has shown that tissue ‘resident’ macrophages are - generated from yolk sac progenitors, expand and differentiate within developing seeded tissues, and self-maintain in adults independently of HSC. In contrast to HSC-derived macrophages, resident macrophages proliferate locally in steady state and - might self-renew. Thus, two lineages of macrophages coexist in most adult tissues. To critically assess the contribution of resident macrophages to tissue repair/regeneration, this proposal aims to determine their developmental pathway and the - underlying molecular mechanisms that control their renewal and functions in vivo. This project will investigate the control of differentiation and proliferation in the resident macrophage lineage by combining state-of-the-art genetic fate-mapping - approaches with innovative live-imaging in mice. We will develop novel methodologies to visualize the interactions between cell cycle and differentiation, to identify the molecular control of macrophage proliferation and to decipher their specific - role during regeneration. This work will significantly increase our knowledge of the differentiation, proliferation and function of resident macrophages in development and tissue repair and will open new venues of research into the role of - self-renewing macrophages in regeneration and aging. - - 2021-11-30, ongoing project - - - 2016-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - ResidentMacroPhage - - - ERC-2016-STG - - - 715230 - - - - - AUDEERING GMBH - AUDEERING GMBH - - - EUR 149 937,50 - - - Voice Emotion detection by Appraisal Inference - - - EUR 149 937,50 - - - Germany - Germany - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The automated sensing of human emotions has gained a lot of commercial attention lately. For facial and physiological sensing many companies offer first professional products. Recently, voice analytics has become a hot topic, - too, with first companies emerging for the telecom, entertainment, and robot markets (e.g. Sympalog, Aldebaran, etc.). Current vocal emotion detection approaches rely on machine learning where emotions are identified based on a reference set of - expression clips. The drawback of this method is the need to rely on a small set of basic, highly prototypical emotions. Real life emotion detection application fields such as clinical diagnosis, marketing research, media impact analysis, and - forensics and security, require subtle differentiations of feeling states. VocEmoApI will develop a first-of-its-kind proof-of-concept software for vocal emotion detection based on a fundamentally different approach: Focusing on vocal nonverbal - behavior and sophisticated acoustic voice analysis, it will exploit the building blocks of emotional processes. This approach will infer not only basic emotion categories but also much finer distinctions such as subcategories of emotion families and - subtle emotions. The development of VocEmoApI draw’s extensively on the results of the applicant’s Advanced Grant, providing a solid theoretical basis. Market analysis through marketing research partners will be conducted and the prototype software - will be utilized to promote the technology and estimate a product value based on feedback from industry contacts. Strong impact of VocEmoApI on large markets such as household robotics, public security, clinical diagnosis and therapy, call analytics, - and marketing research can expected. - - 2017-04-30, closed project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2015 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Germany - - - VocEmoApI - - - ERC-2015-PoC - - - 680883 - - - - - UNIVERSITE PARIS-SUD - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - JACOBS UNIVERSITY BREMEN GGMBH - UNIVERSITE GRENOBLE ALPES - UNIVERSITE JOSEPH FOURIER GRENOBLE 1 - TECHNISCHE UNIVERSITAET KAISERSLAUTERN - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - UNIWERSYTET SLASKI - THE UNIVERSITY OF SHEFFIELD - UNIVERSITY OF SOUTHAMPTON - THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS - UNIVERSITE DE VERSAILLES SAINT-QUENTIN-EN-YVELINES. - THE UNIVERSITY OF WARWICK - UNIVERSITAT ZURICH - LOGILAB - SIMULA RESEARCH LABORATORY AS - UNIVERSITEIT GENT - EUROPEAN X-RAY FREE-ELECTRON LASERFACILITY GMBH - FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG - - - EUR 7 633 845,50 - - - Open Digital Research Environment Toolkit for the Advancement of Mathematics - - - EUR 7 643 071,25 - - - France - France - Germany - France - France - Germany - United Kingdom - Poland - United Kingdom - United Kingdom - United Kingdom - France - United Kingdom - Switzerland - France - Norway - Belgium - Germany - Germany - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - - OpenDreamKit will deliver a flexible toolkit enabling research groups to set up Virtual Research Environments, customised to meet the varied needs of research projects in pure mathematics and applications and supporting the - full research life-cycle from exploration, through proof and publication, to archival and sharing of data and code. - - 2019-08-31, ongoing project | - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.3."> - - - EINFRA-9-2015 - e-Infrastructures for virtual research environments (VRE) - - - RIA - Research and Innovation action - - - France - - - OpenDreamKit - - - H2020-EINFRA-2015-1 - - - 676541 - - - - - UNIVERSITAET HAMBURG - UNIVERSITY OF PLYMOUTH - FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA - THE UNIVERSITY OF HERTFORDSHIRE HIGHER EDUCATION CORPORATION - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - DANIELI TELEROBOT LABS S.R.L. - - - EUR 3 106 495,20 - - - Safety Enables Cooperation in Uncertain Robotic Environments - - - EUR 3 106 495,20 - - - Germany - United Kingdom - Italy - United Kingdom - Germany - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Chiara Andreoli - Tel.: +3901071781854 - Fax: +39 010 7170817 - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The majority of existing robots in industry are pre-programmed robots working in safety zones, with visual or auditory warning signals and little concept of intelligent safety awareness necessary for dynamic and unpredictable - human or domestic environments. In the future, novel cognitive robotic companions will be developed, ranging from service robots to humanoid robots, which should be able to learn from users and adapt to open dynamic contexts. The development of such - robot companions will lead to new challenges for human-robot cooperation and safety, going well beyond the current state of the art. Therefore, the SECURE project aims to train a new generation of researchers on safe cognitive robot concepts for - human work and living spaces on the most advanced humanoid robot platforms available in Europe. The fellows will be trained through an innovative concept of project-based learning and constructivist learning in supervised peer networks where they - will gain experience from an intersectoral programme involving universities, research institutes, large and SME companies from public and private sectors. The training domain will integrate multidisciplinary concepts from the fields of cognitive - human-robot interaction, computer science and intelligent robotics where a new approach of integrating principles of embodiment, situation and interaction will be pursued to address future challenges for safe human-robot environments. - - 2019-08-31, ongoing project | - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - SECURE - - - H2020-MSCA-ITN-2014 - - - 642667 - - - - - RIJKSUNIVERSITEIT GRONINGEN - - - EUR 177 598,80 - - - Aptamer nanostructures dual-targeted to the HER receptor family for cancer therapy - - - EUR 177 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - The proposed research programme deals with the development of aptamer nanostructures for targeted cancer therapy. Immunotherapy encompasses a growing field of anti-cancer therapeutics that target cancer cells expressing - specific antigens, such as members of the HER receptor. Currently, immunoglobulins directed to HER1, better known as EGFR, and HER2 are used in the clinical management of several types of cancer. There are, however, several disadvantages associated - with the production and application of immunoglobulins. Moreover, there is evidence that dual-targeting of multiple receptors at the same time is advantageous for improving clinical outcome and reducing drug resistance. Aptamers, which are short - single-stranded oligonucleotides that can bind a target molecule in a similar fashion as immunoglobulins, may form, due to their physicochemical properties, a superior alternative strategy for targeted cancer therapy. In ADHERE, I will design (WP1) - and investigate in vitro (WP2) and in vivo (WP3) the use of aptamer nanostructures with bispecific (against both EGFR and HER2) and multivalent (up to 4 binding ligands) targeting properties for cancer cell targeting. - - 2018-02-28, Grant Agreement terminated - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Netherlands - - - ADHERE - - - H2020-MSCA-IF-2015 - - - 707229 - - - - - INSTITUT PASTEUR - - - EUR 264 668,40 - - - Elucidating the role of m6A RNA methylation on the replication and pathogenesis of influenza A virus. - - - EUR 264 668,40 - - - France - - - Research Organisations - - It has recently become apparent that post-transcriptional editing of mRNA by methylation of adenosines (m6A) plays a key role in regulating gene expression. In particular, total loss of m6A editing blocks the development of - early embryos in a number of organisms. However, how m6A modifications, which are added in the nucleus and primarily detected by 3 cytoplasmic “reader” proteins, exert their effects remains unknown. The presence of m6A on viral transcripts has been - known for 40 years, yet has only recently been shown to enhance HIV-1 gene expression and replication. Influenza A virus (IAV) that, like HIV-1, replicates in the nucleus, is known to bear a high level of m6A on viral RNA. However, whether and how - m6A editing affects IAV replication remains unknown. Here, the researcher proposes the investigation of the role of m6A in IAV pathogenesis. The main objectives of this proposal are; to compile a precise map of m6A sites on IAV-PR8 RNA, determine - their functional significance on replication and RNA trafficking, assess how m6A machinery is altered in IAV infected cells, and evaluate the conservation of these sites across additional pathogenic IAV strains. - - 2020-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - France - - - IAV-m6A - - - H2020-MSCA-IF-2016 - - - 747810 - - - - - UNIVERSITE DE MONTPELLIER - UNIVERSITEIT LEIDEN - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - SLOVENSKA TECHNICKA UNIVERZITA V BRATISLAVE - FUNDACIO INSTITUT DE CIENCIES FOTONIQUES - INSTITUT PASTEUR - THE MANCHESTER METROPOLITAN UNIVERSITY - ACQUIFER AG - TATRAMED SOFTWARE SRO - PHASEVIEW - - - EUR 3 562 028,64 - - - Training European Experts in Multilevel Bioimaging, Analysis and Modelling of Vertebrate Development and Disease - - - EUR 3 562 028,64 - - - France - Netherlands - France - United Kingdom - Slovakia - Spain - France - United Kingdom - Germany - Slovakia - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - This proposal sprang from European scientists in both academia and industry who identified a common challenge: setting up a training frame to educate the next generation of imagers in complex biological systems (healthy & - pathological), so they are able to master all major aspects of this competitive field and bring important innovations to universities and companies. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - France - - - ImageInLife - - - H2020-MSCA-ITN-2016 - - - 721537 - - - - - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - - - EUR 171 460,80 - - - Development of a Microwave Assisted Cell Disruption of Biomass and Extraction of Valuable Compounds - - - EUR 171 460,80 - - - Germany - - - Research Organisations - - The combination of biomass valorisation, process intensification and green technology is an attractive research challenge for the European Community being in line with the “Resource-efficient Europe” flagship initiatives by - optimizing the use of material, energy resources and gaining valuable products with lower impact on our environment and health. The AMICREX project accepts this challenge and aims to develop an integrated process design for future industrial - implementation, where by-products from agro industrial processes (e.g. carrot peels) can be valorised by recovering high- value nonpolar components (e.g. carotenoids, well recognized natural pigments and widely used in the food and cosmetic - industries) through a microwave intensified microemulsion extraction process. The AMICREX concept can be extended to address the challenges proposed by extraction of nonpolar metabolites, especially carotenoids, from other renewable biomass sources - (e.g. Microalgae). The key aspects of the proposed technology are 1) avoid the use of hazardous organic solvents in nonpolar compounds’ extraction by using microemulsion as extraction media, and 2) improve extraction kinetics by microwave cell - disruption method in order to liberate intracellular compounds and make them available for the subsequent extraction process. - - 2018-09-09, ongoing project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - Amicrex - - - H2020-MSCA-IF-2014 - - - 661198 - - - - - TEL AVIV UNIVERSITY - TEL AVIV UNIVERSITY - - - EUR 1 696 888 - - - Understanding Deep Face Recognition - - - EUR 1 696 888 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Face recognition is a fascinating domain: no other domain seems to present as much value when analysing casual photos; it is one of the few domains in machine learning in which millions of classes are routinely learned; and - the trade-off between subtle inter-identity variations and pronounced intra-identity variations forms a unique challenge. - - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Israel - - - DeepFace - - - ERC-2016-COG - - - 725974 - - - - - INSTITUT PASTEUR - INSTITUT PASTEUR - - - EUR 150 000 - - - RNA virus attenuation by altering mutational robustness - - - EUR 150 000 - - - France - France - - - Research Organisations - Research Organisations - - RNA viruses have extreme mutation frequencies. When a RNA virus replicates, nucleotide mutations are generated resulting in a population of variants. This genetic diversity creates a cloud of mutations that are potentially - beneficial to viral survival, but the majority of mutations are detrimental to the virus. By increasing the mutation rate of a RNA virus, viral fitness is reduced because it generates more errors, and attenuates the virus during in vivo infection. - Another feature that affects RNA virus fitness is mutational robustness. Mutational robustness is the ability to buffer the negative effects of mutation. - - - 2018-02-28, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - France - - - 1toStopVax - - - ERC-2016-PoC - - - 727758 - - - - - UNIVERSIDADE DO PORTO - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - EFACEC ENGENHARIA E SISTEMAS SA - GREATCELL SOLAR UK LIMITED - INSTYTUT CHEMII FIZYCZNEJ POLSKIEJ AKADEMII NAUK - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSITAET ULM - - - EUR 2 993 403,50 - - - New technological advances for the third generation of Solar cells - - - EUR 2 993 403,75 - - - Portugal - Switzerland - Portugal - United Kingdom - Poland - France - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - - It is believed that solid-state perovskite solar cells (PSCs) will be the next generation of power source, contributing for fostering the use of photovoltaics in buildings’ roofs and facades. Actually, their transparency, - various possibilities of colors and high kWh/nominal power ratio offer to PSCs an opportunity to conquer markets that are not attainable by traditional silicon solar cells. To turn this ambition to a marketable product several efforts are still - needed and this project aims to give relevant answers to those key challenges. - - 2018-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-1-2014 - FET-Open research projects - - - RIA - Research and Innovation action - - - Portugal - - - GOTSolar - - - H2020-FETOPEN-2014-2015-RIA - - - 687008 - - - - - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - KARLSRUHER INSTITUT FUER TECHNOLOGIE - COVESTRO DEUTSCHLAND AG - AVANZARE INNOVACION TECNOLOGICA SL - GVS S.P.A. - UNIVERSIDADE DO MINHO - UNIVERSITEIT TWENTE - PROMOLDING BV - - - EUR 3 794 898,96 - - - European Training Network to Accelerate the Development Chain of Nanostructured Polymers - - - EUR 3 794 898,96 - - - Germany - United Kingdom - Greece - Germany - Germany - Spain - Italy - Portugal - Netherlands - Netherlands - - - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Research and training in TheLink spans the material development chain for nanostructured polymers. These materials, including phase separated polymers and composites, are attracting scientific and industrial interest due to - the outstanding properties and functionalities that can be achieved. However, to exploit the potential of these materials an in-depth understanding of the relationship between nano/micro structures and macro-level properties is required. - - 2018-10-31, ongoing project - - - 2014-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - TheLink - - - H2020-MSCA-ITN-2014 - - - 642890 - - - - - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH - WIRTSCHAFTSUNIVERSITAT WIEN - FEI ELECTRON OPTICS BV - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN - KARLSRUHER INSTITUT FUER TECHNOLOGIE - UNIVERSITY OF GLASGOW - UNIVERSITE DE GENEVE - AMS AG - CIS FORSCHUNGSINSTITUT FUR MIKROSENSORIK GMBH - - - EUR 3 872 524,56 - - - Smart Sensor Technologies and Training for Radiation Enhanced Applications andMeasurements - - - EUR 3 872 524,56 - - - Switzerland - Austria - Netherlands - Germany - France - Germany - Germany - United Kingdom - Switzerland - Austria - Germany - - - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - - STREAM is a 4-year multi-site training network that aims at career development of Early Stage Researchers (ESRs) on - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Switzerland - - - STREAM - - - H2020-MSCA-ITN-2015 - - - 675587 - - - - - TTY-SAATIO - MITTUNIVERSITETET - UNIVERSITAT DE VALENCIA - UNIVERSITY OF NEWCASTLE UPON TYNE - CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - HOLOGRAFIKA HOLOGRAMELOALLITO FEJLESZTO ES FORGALMAZO KFT - RAYTRIX GMBH - - - EUR 3 801 840,48 - - - European Training Network on Full Parallax Imaging - - - EUR 3 801 840,48 - - - Finland - Sweden - Spain - United Kingdom - Germany - Germany - Hungary - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Current displays fall far short of truly recreating visual reality. This can never be achieved by painting an image on a flat surface such as a TV screen, but requires a full-parallax display which can recreate the complete - lightfield, i.e. the light traveling in every direction through every point in space. Recent years have seen major developments towards this goal, promising a new generation of ultra-realistic displays with applications in medicine, informatics, - manufacturing, entertainment, gaming and more. However, achieving this will require a new generation of researchers trained both in the relevant physics, and in the biology of human vision. The European Training Network on Full-Parallax Imaging - (ETN-FPI) aims at developing this new generation. The research concept of the network is to depart from the notations of plenoptics, light field and integral imaging, used sometimes interchangeably, and to harmonize and advance further the research - in these areas under the umbrella of the wider and viewer-centred FPI concept. Fifteen early-stage researchers will be employed on novel inter-disciplinary FPI projects. The training disciplines include theoretical and applied optics, - multi-dimensional image processing, and visual neuroscience. The targeted applications range from plenoptic microscopy to interaction with visual content generated by wide field-of-view displays. Extensive studies on perception of continuous parallax - and subjective tests on various displays are planned. The training program includes local training, online seminars, workshops, training schools and a conference. The researchers trained within the network are expected to gather competitive skills - and become highly competent in bringing innovations to the field of ultra-realistic and interactive visual media. This will enhance their employability in a rapidly growing sector in academia and industry and position Europe as a leader in this - emerging multidisciplinary field. - - 2019-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Finland - - - ETN-FPI - - - H2020-MSCA-ITN-2015 - - - 676401 - - - - - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - - - EUR 159 460,80 - - - Development of a new immunoassay platform based on porous antibody microparticles - - - EUR 159 460,80 - - - Germany - - - Research Organisations - - Rapid and sensitive analyte determination in small volumes is one of the main tasks in modern diagnostics for the development of miniaturized in vitro test systems. This is critically important for both health and - environmental diagnostics. The traditional approach (ELISA) is a time-consuming multistep process with sensitivity limitations due to usually used planar supports for detection. In this project we intend to develop a new approach for biosensing based - on porous antibody microparticles. For this purpose, the combination of a new technique to assemble porous particles at mild conditions (host know-how) and highly sensitive ELISA-based detection system (applicant know-how) will be used. The porous - particles will work as a platform with two crucial features: i) specific immunochemical reactions are realized on highly developed particle surface, ii) separation and detection in small volumes (micrometer dimensions). We believe that the proposed - approach may open new avenues in future for effective diagnostics. - - 2017-09-30, closed project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - IMPAM - - - H2020-MSCA-IF-2014 - - - 657079 - - - - - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - - - EUR 159 460,80 - - - NANOSTRUCTURED LARGE AREA PLASMONIC SYSTEMSDEPOSITED BY GAS FLOW SPUTTERING AND PLASMA-ENHANCED CVD PROCESSES - - - EUR 159 460,80 - - - Germany - - - Research Organisations - - Nanocomposites made of metallic nanoparticles (e.g. Au, Ag, Cu) embedded in a transparent matrix may display unique optical properties due to plasmonic effects resulting from the interaction of light with particles of - nanometric size. This original behavior can be exploited in a wide range of applications including chemical and bio-sensors with extremely high sensitivity, spectroscopy, solar energy harvesting, and nanophotonics. - - 2017-03-31, closed project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - NanoLAPS - - - H2020-MSCA-IF-2014 - - - 655628 - - - - - BILKENT UNIVERSITESI VAKIF - - - EUR 157 845,60 - - - Quantifying and Protecting the Privacy of Genomic Data - - - EUR 157 845,60 - - - Turkey - - - Higher or Secondary Education Establishments - - Genomic data carries a lot of sensitive information about its owner such as his predispositions to sensitive diseases, ancestors, physical attributes, and genomic data of his relatives (leading to interdependent privacy - risks). Individuals share vast amount of information on the Web, and some of this information can be used to infer their genomic data. Hence, there is a need to clearly understand the privacy risks on genomic data of individuals considering publicly - available information on the Web. It is also crucial to protect genomic privacy of individuals without compromising the utilization of genomic data in research and healthcare. - - 2018-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Turkey - - - GenoPri - - - H2020-MSCA-IF-2015 - - - 707135 - - - - - FUNDACIO CENTRE DE REGULACIO GENOMICA - - - EUR 158 121,60 - - - Detection of Chromatin Bridges during Cytokinesis - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - Duplication of the genome and its division into two daughter cells during mitosis is vital for survival of the organism. Cells have multiple mechanisms to ensure that this process is accomplished correctly thereby preserving - the integrity of the genome. The final check before cell division is made by the NoCut abscission pathway. In yeast and animal cells, this mechanism monitors completion of chromosome separation, delaying abscission when chromosome bridges spanning - the division site are detected. - - - 2018-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - NoCut - - - H2020-MSCA-IF-2015 - - - 705602 - - - - - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - - - EUR 1 907 325 - - - Self-replicating Colloidal Assemblies - - - EUR 1 907 325 - - - Germany - Germany - - - Research Organisations - Research Organisations - - Self-replication is the preeminent property of living systems and natural materials. Nature builds and repairs by self-replication. Purely synthetic materials so far lack this important ability. An indispensable prerequisite - is the multi-directional control of interactions between the building blocks of materials. In order to generate colloidal building blocks, which are able to self-replicate in a non-biological two-step process, i.e. without the use of DNA, we propose - to create a new class of patchy colloidal particles bearing three patches of two different chemical functionalities. The new production process will yield precise control over the patch location and chemistry and thus also gives particles that go - well beyond known ABA- or ABC-type Janus particles. - - - 2020-06-30, ongoing project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - REPLICOLL - - - ERC-2014-CoG - - - 648365 - - - - - STICHTING EGI - OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN - VLAAMS INSTITUUT VOOR DE ZEE VZW - INSTITUTE OF INFORMATION AND COMMUNICATION TECHNOLOGIES - SWISS NATIONAL GRID ASSOCIATION (SWING) - CESNET ZAJMOVE SDRUZENI PRAVNICKYCH OSOB - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - GESELLSCHAFT FUR WISSENSCHAFTLICHE DATENVERARBEITUNG MBH GOTTINGEN - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - CSC-TIETEEN TIETOTEKNIIKAN KESKUS OY - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE - ETHNIKO DIKTYO EREVNAS TECHNOLOGIAS AE - SVEUCILISTE U ZAGREBU SVEUCILISNI RACUNSKI CENTAR - MAGYAR TUDOMANYOS AKADEMIA SZAMITASTECHNIKAI ES AUTOMATIZALASI KUTATOINTEZET - ISTITUTO NAZIONALE DI FISICA NUCLEARE - CONSORZIO INTERUNIVERSITARIO RISONANZE MAGNETICHE DI METALLO PROTEINE - PROVINCIA LOMBARDO VENETA - ORDINEOSPEDALIERO DI SAN GIOVANNI DI DIO- FATEBENEFRATELLI - CONSIGLIO NAZIONALE DELLE RICERCHE - ENGINEERING - INGEGNERIA INFORMATICA SPA - SURFSARA BV - AKADEMIA GORNICZO-HUTNICZA IM. STANISLAWA STASZICA W KRAKOWIE - LABORATORIO DE INSTRUMENTACAO E FISICA EXPERIMENTAL DE PARTICULAS - ICETA INSTITUTO DE CIENCIAS, TECNOLOGIAS E AGROAMBIENTE DA UNIVERSIDADE DO PORTO - UPPSALA UNIVERSITET - USTAV INFORMATIKY, SLOVENSKA AKADEMIA VIED - TURKIYE BILIMSEL VE TEKNOLOJIK ARASTIRMA KURUMU - SCIENCE AND TECHNOLOGY FACILITIES COUNCIL - BIOBANKS AND BIOMOLECULAR RESOURCES RESEARCH INFRASTRUCTURE CONSORTIUM (BBMRI-ERIC) - EUROPEAN MOLECULAR BIOLOGY LABORATORY - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH - EISCAT SCIENTIFIC ASSOCIATION - FOOD AND AGRICULTURE ORGANIZATION OF THE UNITED NATIONS FAO - AGROKNOW IKE - MAAT France - THE TRUSTEES OF INDIANA UNIVERSITY - ACADEMIA SINICA - ADVANCED SCIENCE AND TECHNOLOGY INSTITUTE - INSTITUT TEKNOLOGI BANDUNG - UNIVERSITI PUTRA MALAYSIA - - - EUR 8 000 000 - - - Engaging the EGI Community towards an Open Science Commons - - - EUR 8 650 001,50 - - - Netherlands - Austria - Belgium - Bulgaria - Switzerland - Czech Republic - Germany - Germany - Spain - Finland - France - France - Greece - Croatia - Hungary - Italy - Italy - Italy - Italy - Italy - Netherlands - Poland - Portugal - Portugal - Sweden - Slovakia - Turkey - United Kingdom - Austria - Germany - Switzerland - Sweden - Italy - Greece - France - United States - Taiwan - Philippines - Indonesia - Malaysia - - - Other - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Other - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Other - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Over the last decade, the European Grid Infrastructure (EGI) has built a distributed computing and data infrastructure to support over 21,000 researchers from many disciplines with unprecedented data analysis capabilities. EGI - builds on the European and national investments and relies on the expertise of EGI.eu - a not-for-profit foundation that provides coordination to the EGI Community, including user groups, EGI.eu participants in the EGI Council, and the other - collaborating partners. - - 2017-08-31, closed project - - - 2015-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.3."> - - - EINFRA-1-2014 - Managing, preserving and computing with big research data - - - RIA - Research and Innovation action - - - Netherlands - - - EGI-Engage - - - H2020-EINFRA-2014-2 - - - 654142 - - - - - UNIVERSITY OF STRATHCLYDE - UNIVERSITY OF GLASGOW - UNIVERSITE DE PAU ET DES PAYS DE L'ADOUR - UNIVERSITA DEGLI STUDI DI CASSINO E DEL LAZIO MERIDIONALE - UNIVERSITY OF DURHAM - UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II. - INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE - TECHNISCHE UNIVERSITEIT DELFT - CENTRE DE COOPERATION INTERNATIONALE EN RECHERCHE AGRONOMIQUE POUR LEDEVELOPPEMENT - C.I.R.A.D. EPIC - CENTRE INTERNACIONAL DE METODES NUMERICS EN ENGINYERIA - LIMITSTATE LIMITED - NOBATEK - KEMPFERT GEOTECHNIK GMBH - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - - - EUR 3 954 945,78 - - - Training Engineers and Researchers to Rethink geotechnical Engineering for a low carbon future - - - EUR 3 954 945,78 - - - United Kingdom - United Kingdom - France - Italy - United Kingdom - Italy - France - Netherlands - France - Spain - United Kingdom - France - Germany - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - TERRE aims to develop novel geo-technologies to address the competitiveness challenge of the European construction industry in a low carbon agenda. It will be delivered through an inter-sectoral and intra-European coordinated - PhD programme focused on carbon-efficient design of geotechnical infrastructure. Industry and Research in the construction sector have been investing significantly in recent years to produce innovative low-carbon technologies. However, little - innovation has been created in the geo-infrastructure industry, which is lagging behind other construction industry sectors. TERRE aims to close this gap through a network-wide training programme carried out by a close collaboration of eleven - Universities and Research Centres and three SMEs. It is structured to provide a balanced combination of fundamental and applied research and will eventually develop operational tools such as software for low-carbon geotechnical design and a Decision - Support System for infrastructure project appraisal. The research fellows will be involved in inter-sectoral and intra-European projects via enrolment in 8 ‘Joint-Awards’ and 7 ‘Industrial’ PhDs. The research fellows will be trained in low-carbon - design by developing novel design concepts including eco-reinforced geomaterials, ‘engineered’ vegetation, engineered soil-atmosphere interfaces, biofilms, shallow geothermal energy and soil carbon sequestration. Distinctive features of TERRE are the - supervision by an inter-sectoral team and the orientation of the research towards technological applications. Training at the Network level includes the development of entrepreneurial skills via a special programme on ‘Pathways to Research - Enterprise’ to support the research fellows in establishing and leading spin-out companies after the end of the project. - - 2019-10-31, ongoing project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - TERRE - - - H2020-MSCA-ITN-2015 - - - 675762 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - ECOLE FRANCAISE DE ROME - - - EUR 1 999 182,94 - - - Promoting, Patronising and Practising the Arts in Roman Aristocratic Families (1644-1740). The Contribution of Roman Family Archives to the History of Performing Arts - - - EUR 1 999 182,94 - - - France - France - Italy - - - Research Organisations - Research Organisations - Research Organisations - - Rome, centre of the Catholic Church and capital of the Papal States, strewn with churches and religious institutions, was also, in the 17th and 18th centuries, the scene of intense conflicts and rivalries between some twenty - leading aristocratic families, highly adept at organising musical, theatrical and choreographic performances to display their political sympathies. The artistic life that animated the palaces and country villas of this elite has been far less studied - than that of the papal court, the grand theatres or the principal churches of Rome. The PERFORMART project aims to enrich our understanding of the history of performing arts among the Roman nobility between 1644 and 1740 by exploiting the abundant - documentation contained in the archives of eleven leading aristocratic families. The present proposal arises from the previous research of the principal investigator in the Orsini-Lante Archives. For the first time, PERFORMART will bring together - specialised archivists and historians, all expert in different aspects of this micro-society, in a systematic collaboration between the history of the performing arts, choreographic studies, and art, music, social, and economic history. Via a - relational database, this collaboration will bring to light original sources able to elucidate the social and artistic practices of Roman families, the motivations and conditions of patronage, the material framework of artistic productions, the - status of the artist and his degree of dependence on his protectors, and, finally, the political, local and international impact of the involvement of these noble families on the artistic life of Rome. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - France - - - PERFORMART - - - ERC-2015-CoG - - - 681415 - - - - - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - UNIVERSITAT LINZ - RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN - BUNDESANSTALT FUER MATERIALFORSCHUNG UND -PRUEFUNG - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - HIGH TECH COATINGS GMBH - - - EUR 3 024 827 - - - Laser-induced Nanostructures as Biomimetic Model of Fluid Transport in the Integument of Animals - - - EUR 3 024 827,50 - - - Greece - Spain - Austria - Germany - Germany - Germany - Austria - - - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The integument of an animal body has various functions, which are often achieved by specific micro- and/or nano- hierarchical structures. Examples are the very low water friction and air retention of water spiders or the swim - fern of salvinia and the outstanding adhesion properties of geckos. In this project, we will employ advanced laser-processing strategies based on self-organization, to mimic the specific topography and the excellent wetting properties of the - integument of bark bugs and moisture harvesting lizards resulting from adaptations to their environment. Flat bark bugs darken during rain fall due to a super-wettable body surface with capillaries out of which water spreads onto plain areas of the - bug. For moisture harvesting in lizards wettability takes place in opposed direction, i.e. from plain areas into a capillary network on the skin. A fast and directional transport results from a special geometry of capillaries. Thus as general - objective we want to test whether both effects, i.e. fast capillary transport (lizard) and liquid spreading onto plain areas (bark bugs), can be combined by optimized structures with hierarchical geometry. The outcome of this innovative biomimetic - exploitation of wetting effects is expected to lead to a radically new technological approach of laser-generated surface textures on micro- and nanometer scale. Especially for control of friction and wear in liquids, leveraging new results can be - expected, e.g. for developing slide bearings. The extension of surface structures over large areas is feasible. Thus, laser-fabrication of biomimetic surfaces with extreme wetting properties can be also anticipated in further applications, e.g. - lubrication, water and oil separation, reduced drag in underwater applications, high power device cooling. All related to an innovative and sustainable reduction of CO2 emission. - - 2018-06-30, ongoing project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-1-2014 - FET-Open research projects - - - RIA - Research and Innovation action - - - Greece - - - LiNaBioFluid - - - H2020-FETOPEN-2014-2015-RIA - - - 665337 - - - - - BSH ELECTRODOMESTICOS ESPANA SA - AIRBUS DEFENCE AND SPACE GMBH - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - UNIVERSITEIT TWENTE - UNIVERSIDAD POLITECNICA DE MADRID - CENTRE TECHNOLOGIQUE ALPHANOV - CONSIGLIO NAZIONALE DELLE RICERCHE - THE UNIVERSITY OF BIRMINGHAM - LEIBNIZ-INSTITUT FUR POLYMERFORSCHUNG DRESDEN EV - ROBERT BOSCH GMBH - - - EUR 3 567 962,52 - - - EUROPEAN ESRs NETWORK ON SHORT PULSED LASER MICRO/NANOSTRUCTURING OF SURFACES - - - EUR 3 567 962,52 - - - Spain - Germany - Germany - Netherlands - Spain - France - Italy - United Kingdom - Germany - Germany - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Today, industrial markets demand highly added value products offering new features at a low-cost. To this extent, technologies to modify surfaces instead of creating composites or applying coatings on surfaces can offer new - industrial opportunities. Current state of the art identifies short pulsed(SP)/ultra-short pulsed(USP) laser-material processing as a promising technology for structuring surfaces and thus for embedding new functionalities for industrial - applications. The LASER4FUN research programme pursues to go far beyond the current state through the development of new surface micro/nano-structuring/patterning methods by using emerging SP/USP laser technologies (LIPSS, DLIP, DLW & hybrid - tech). The research will focus on the interaction of laser energy with several materials (metals, semiconductors, polymers, glasses & advanced materials) and on new surface functionalities like tribology, aesthetics and wettability. - - 2019-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Spain - - - LASER4FUN - - - H2020-MSCA-ITN-2015 - - - 675063 - - - - - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - - - EUR 410 093,75 - - - Observing Emergence - - - EUR 410 093,75 - - - Germany - - - Research Organisations - - In line with the mission of the FET programme the overarching aim of OBSERVE is to support Europe to grasp leadership early on in new and emerging technology areas that promise to renew the basis for European competitiveness - and growth and that will make a difference for society in the decades to come. For this purpose OBSERVE addresses the concrete objective of identifying new opportunities and directions for interdisciplinary research towards new and visionary - technology of any kind. More specifically OBSERVE will: - - 2017-05-31, closed project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-2-2014 - Coordination and Support Activities - - - CSA - Coordination and support action - - - Germany - - - OBSERVE - - - H2020-FETOPEN-2014-CSA - - - 665136 - - - - - BAYERISCHE JULIUS-MAXIMILIANS UNIVERSITAT WURZBURG - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - UPPSALA UNIVERSITET - HELMHOLTZ-ZENTRUM BERLIN FUR MATERIALIEN UND ENERGIE GMBH - IOLITEC IONIC LIQUIDS TECHNOLOGIES GMBH - GABO:MI GESELLSCHAFT FUR ABLAUFORGANISATION:MILLIARIUM MBH & CO KG - ARTTIC - - - EUR 3 872 980 - - - Diamond materials for the photocatalytic conversion of CO2 to fine chemicals and fuels using visible light - - - EUR 3 872 981,25 - - - Germany - France - Germany - United Kingdom - Sweden - Germany - Germany - Germany - France - - - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - In DIACAT we propose the development of a completely new technology for the direct photocatalytic conversion of CO2 into fine chemicals and fuels using visible light. The approach utilises the unique property of man-made - diamond, now widely available at low economic cost, to generate solvated electrons upon light irradiation in solutions (e.g. in water and ionic liquids). The project will achieve the following major objectives on the way to the efficient production - of chemicals from CO2: - - 2019-06-30, ongoing project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-1-2014 - FET-Open research projects - - - RIA - Research and Innovation action - - - Germany - - - DIACAT - - - H2020-FETOPEN-2014-2015-RIA - - - 665085 - - - - - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - ARM LIMITED - Eidgenössische Technische Hochschule Zürich - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - SCAPOS AG - THE UNIVERSITY OF MANCHESTER - BULL SAS - VIRTUAL OPEN SYSTEMS - BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION - FORSCHUNGSZENTRUM JULICH GMBH - KALRAY SA - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 8 629 247,50 - - - European Exascale Processor Memory Node Design - - - EUR 8 629 247,50 - - - France - United Kingdom - Switzerland - Greece - Germany - Germany - United Kingdom - France - France - Spain - Germany - France - France - - - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - - ExaNoDe will investigate, develop integrate and validate the building blocks (technology readiness level 5) for a highly efficient, highly integrated, multi-way, high-performance, heterogeneous compute element aimed towards - exascale computing. It will build on multiple European initiatives for scalable computing, utilizing low- power processors and advanced nanotechnologies. ExaNoDe will draw heavily on the Unimem memory and system design paradigm defined within the - EUROSERVER FP7 project, providing low-latency, high-bandwidth and resilient memory access, scalable to Exabyte levels. - - 2018-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.2."> - - - FETHPC-1-2014 - HPC Core Technologies, Programming Environments and Algorithms for Extreme Parallelism and Extreme Data Applications - - - RIA - Research and Innovation action - - - France - - - ExaNoDe - - - H2020-FETHPC-2014 - - - 671578 - - - - - UNIVERSITAT POLITECNICA DE CATALUNYA - STICHTING DELTARES - CHALMERS TEKNISKA HOEGSKOLA AB - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - ASSOCIATION POUR LA RECHERCHE ET LE DEVELOPPEMENT DES METHODES ET PROCESSUS INDUSTRIELS - KATHOLIEKE UNIVERSITEIT LEUVEN - STICHTING KATHOLIEKE UNIVERSITEIT - - - EUR 2 404 943 - - - Global systems Rapid Assessment tools through Constraint FUnctional Languages - - - EUR 2 404 943,75 - - - Spain - Netherlands - Sweden - Germany - France - Belgium - Netherlands - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The making of policies coping with Global Systems is a process that necessarily involves stakeholders from diverse disciplines, each with their own interests, constraints and objectives. People play a central role in such - collective decision making and the quest for solutions to a problem generally intertwines its very specification. - - - 2018-01-31, closed project - - - 2015-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.2."> - - - FETPROACT-1-2014 - Global Systems Science (GSS) - - - RIA - Research and Innovation action - - - Spain - - - GRACeFUL - - - H2020-FETPROACT-2014 - - - 640954 - - - - - THE UNIVERSITY OF EDINBURGH - BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION - KUNGLIGA TEKNISKA HOEGSKOLAN - INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - DEUTSCHES ZENTRUM FUER LUFT - UND RAUMFAHRT EV - T-SYSTEMS SOLUTIONS FOR RESEARCH GMBH - UNIVERSITAT JAUME I DE CASTELLON - THE UNIVERSITY OF MANCHESTER - - - EUR 3 861 400,99 - - - Programming Model INTERoperability ToWards Exascale (INTERTWinE) - - - EUR 3 861 400,99 - - - United Kingdom - Spain - Sweden - France - Germany - Germany - Germany - Spain - United Kingdom - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project addresses the problem of programming model design and implementation for the Exascale. The first Exascale computers will be very highly parallel systems, consisting of a hierarchy of architectural levels. To - program such systems effectively and portably, programming APIs with efficient and robust implementations must be ready in the appropriate timescale. A single, “silver bullet” API which addresses all the architectural levels does not exist and seems - very unlikely to emerge soon enough. We must therefore expect that using combinations of different APIs at different system levels will be the only practical solution in the short to medium term. Although there remains room for improvement in - individual programming models and their implementations, the main challenges lie in interoperability between APIs. It is this interoperability, both at the specification level and at the implementation level, which this project seeks to address and - to further the state of the art. INTERTWinE brings together the principal European organisations driving the evolution of programming models and their implementations. The project will focus on seven key programming APIs: MPI, GASPI, OpenMP, OmpSs, - StarPU, QUARK and PaRSEC, each of which has a project partner with extensive experience in API design and implementation. Interoperability requirements, and evaluation of implementations will be driven by a set of kernels and applications, each of - which has a project partner with a major role in their development. The project will implement a co- design cycle, by feeding back advances in API design and implementation into the applications and kernels, thereby driving new requirements and hence - further advances. - - 2018-09-30, ongoing project | - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.2."> - - - FETHPC-1-2014 - HPC Core Technologies, Programming Environments and Algorithms for Extreme Parallelism and Extreme Data Applications - - - RIA - Research and Innovation action - - - United Kingdom - - - INTERTWINE - - - H2020-FETHPC-2014 - - - 671602 - - - - - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - ICEOTOPE RESEARCH & DEVELOPMENT LTD - ALLINEA SOFTWARE LIMITED - ENGINSOFT SPA - EXACT LAB SRL - MONETDB SOLUTIONS B.V. - VIRTUAL OPEN SYSTEMS - ISTITUTO NAZIONALE DI ASTROFISICA - ISTITUTO NAZIONALE DI FISICA NUCLEARE - THE UNIVERSITY OF MANCHESTER - UNIVERSITAT POLITECNICA DE VALENCIA - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - - - EUR 8 442 547,50 - - - European Exascale System Interconnect and Storage - - - EUR 8 442 547,50 - - - Greece - United Kingdom - United Kingdom - Italy - Italy - Netherlands - France - Italy - Italy - United Kingdom - Spain - Germany - - - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - ExaNeSt will develop, evaluate, and prototype the physical platform and architectural solution for a unified Communication and Storage Interconnect and the physical rack and environmental structures required to deliver - European Exascale Systems. The consortium brings technology, skills, and knowledge across the entire value chain from computing IP to packaging and system deployment; and from operating systems, storage, and communication to HPC with big data - management, algorithms, applications, and frameworks. Building on a decade of advanced R&D, ExaNeSt will deliver the solution that can support exascale deployment in the follow-up industrial commercialization phases. Using direction from the - ETP4HPC roadmap and soon-available high density and efficiency compute, we will model, simulate, and validate through prototype, a system with: - - 2018-11-30, ongoing project - - - 2015-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.2."> - - - FETHPC-1-2014 - HPC Core Technologies, Programming Environments and Algorithms for Extreme Parallelism and Extreme Data Applications - - - RIA - Research and Innovation action - - - Greece - - - ExaNeSt - - - H2020-FETHPC-2014 - - - 671553 - - - - - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH - - - EUR 383 593,50 - - - Tracing impacts of the FET programme - - - EUR 383 593,75 - - - Germany - Austria - - - Research Organisations - Research Organisations - - The FET_Traces project will measure and assess the direct and indirect impacts of the FET programme on the science and technology landscape and its perception by individual researchers who are potential proposers for FET Open - and FET Proactive projects. The impact assessment will be based on a comprehensive theoretic foundation, it will develop a targeted indicator set covering central aspects of the FET mission like novelty, multi-disciplinarity, innovation eco-systems, - and becoming a relevant player in the European funding landscape. - - - 2017-11-14, closed project - - - 2015-07-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-2-2014 - Coordination and Support Activities - - - CSA - Coordination and support action - - - Germany - - - FET_TRACES - - - H2020-FETOPEN-2014-CSA - - - 665083 - - - - - UNIVERSITAT POLITECNICA DE VALENCIA - - - EUR 158 121,60 - - - ZEolitic reactor hosting Subphthalocyanines and Metal Oxides as photocatalytic system for opto-electronic applications - - - EUR 158 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - Solar light promoted CO2 reduction could be the “greenest” alternative to fossil fuels as it would also decrease the atmospheric CO2 emissions. ZESMO comes from the idea of developing an efficient, robust and low-cost - photocatalytic system to improve reported conversion rates for CO2 reduction by H2O. Some of the problems to overcome are the limited wavelength response (frequently limited to only 4% of the total solar light energy), photo-corrosion and low quantum - efficiencies. The photocatalyst presented in this proposal is designed to tackle these issues and achieve a better performance by incorporating Suphthalocyanine (SubPc) (light harvester) and metal clusters (semiconductor) into zeolites. Zeolite’s - pores act as “nano-reactors” entrapping both species and enhancing chemical stability and catalytic activity. The second part of the project deals with the evaluation of the photocatalytic activity of a series of synthesised hybrids. The system will - be subjected to operation lifetime studies for its possible future commercialisation. - - - 2018-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - ZESMO - - - H2020-MSCA-IF-2015 - - - 709023 - - - - - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - KUNGLIGA TEKNISKA HOEGSKOLAN - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - SCUOLA NORMALE SUPERIORE - SYDDANSK UNIVERSITET - ECOLE NATIONALE SUPERIEURE DE CHIMIE DE PARIS - NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU - DANMARKS TEKNISKE UNIVERSITET - - - EUR 3 745 978,92 - - - Training network for COmputational Spectroscopy In Natural sciences and Engineering - - - EUR 3 745 978,92 - - - Germany - Sweden - Germany - Italy - Denmark - France - Norway - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - During the last two decades, ab-initio Quantum Chemistry has become an important scientific pillar in chemical research. For electronic ground states, well established theoretical research tools exist, that can be applied by - scientists in order to guide experimental interpretation and synthesis design. For optical properties and excited electronic states, dominated by electron correlation, computational tools are lagging behind and are currently missing the accuracy - needed in order to have predictive power. However, such tools are urgently required for the fundamental understanding of natural photo-initiated processes as well as organic optical devices. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - COSINE - - - H2020-MSCA-ITN-2017 - - - 765739 - - - - - UNIVERSIDADE DE AVEIRO - HELMHOLTZ-ZENTRUM GEESTHACHT ZENTRUM FUR MATERIAL- UND KUSTENFORSCHUNG GMBH - LATVIJAS UNIVERSITATES POLIMERU MEHANIKAS INSTITUTS - SMALLMATEK - SMALL MATERIALS AND TECHNOLOGIES LDA - SYNPO AKCIOVA SPOLECNOST - - - EUR 900 000 - - - Development of Smart Nano and Microcapsulated Sensing Coatings for improving of Material Durability/Performance - - - EUR 900 000 - - - Portugal - Germany - Latvia - Portugal - Czech Republic - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The proposal aims to develop an innovative approach to impart sensing functionality and detect substrate degradation. The degradation processes targeted will be corrosion of metallic substrates and mechanical damage by impact - on fibre reinforced plastics and composites (FRP), used as structural components in the vehicle industry worldwide. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Portugal - - - SMARCOAT - - - H2020-MSCA-RISE-2014 - - - 645662 - - - - - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - - - EUR 159 460,80 - - - High efficiency GaInP/GaAs Tandem wafer bonded solar cell on silicon - - - EUR 159 460,80 - - - Germany - - - Research Organisations - - Direct conversion of photons into electricity is a promising clean energy solution to answer the challenge of energy supply security, competitiveness of the EU industry, electricity prices and climate change. Monocrystalline - silicon (c-Si), the dominant technology on the photovoltaic (PV) market, benefits from a strong industry and record power conversion efficiency of 25%, with a cost decreasing every year. However, c-Si technology, mainly limited by material - properties, has very little room for efficiency improvement. Much higher efficiencies has been achieved by stacking diodes made of III-V semiconductors; but for cost and availability reasons, the III-V solar cells are restricted to specific markets - (space & terrestrial concentration). A hybrid solution combining the advantages III-V multi-junction cells with the benefits of Si, the most wide-spread PV material, offers great opportunities. Indeed, efficiencies up to 35% under 1-sun AM1.5G - conditions is expected for a triple junction device based on conventional c-Si cells combined with additional (Al)GaAs and GaInP pn-junctions (4 µm of III-V material on top of a c-Si wafer). However the direct epitaxial growth of (Al)GaAs & GaInP - on Si is highly mismatched and sufficient material quality has not been achieved so far. The innovative approach proposed in this project bypass the mismatch and enables to combine high crystal quality III-V compounds with Si through wafer bonding: - III-V layers are grown lattice matched on GaAs or Ge and then bonded to Si, followed by substrate lift-off & re-use. The validity of the approach has been proven at Fraunhofer ISE with un-optimized GaInP/GaAs//Si triple-junction solar cells with - >25% efficiency. This research project, relying on modeling and experimental work to optimize the cell structure (light trapping, bond interface quality, current matching, etc.), targets the significant breakthrough of a GaInP/GaAs//Si triple - junction reaching >30% efficiency on large areas (>4cm2). - - 2017-05-31, closed project | - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - HISTORIC - - - H2020-MSCA-IF-2014 - - - 655272 - - - - - UNIVERSITAT DE GIRONA - EASY INNOVA S.L. - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - ADMIN LEUVEN bvba - - - EUR 378 000 - - - Social, complementary or community virtual currencies transfer of knowledge to SME: a new era for competitiveness and entrepreneurship - - - EUR 378 000 - - - Spain - Spain - Germany - Belgium - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - With the advent of social networks and Mobile networks, new online communities are being created around sustainable topics (environmental, social, community development). The phenomena, known as digital social innovation, - generates a positive ecosystem where business and social development enabled with new behaviours boosted by social, complementary or community currencies deployed as virtual currencies have a great potential for competitiveness, and entrepreneurship, - but also for fostering social responsibility in Europe. - - - 2016-11-30, closed project - - - 2014-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Spain - - - VirCoin2SME - - - H2020-MSCA-RISE-2014 - - - 645767 - - - - - AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - CENTRE FOR RENEWABLE ENERGY SOURCES AND SAVING FONDATION - European Distributed Energy Resources Laboratories e.V. - DNV GL NETHERLANDS B.V. - KEMA NEDERLAND BV - DANMARKS TEKNISKE UNIVERSITET - ENEL INGEGNERIA E RICERCA SPA - ENEL PRODUZIONE SPA - INSTITUT POLYTECHNIQUE DE GRENOBLE - INSTITUTE OF COMMUNICATION AND COMPUTER SYSTEMS - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - ORMAZABAL CORPORATE TECHNOLOGY, A.I.E. - OFFIS EV - RICERCA SUL SISTEMA ENERGETICO - RSE SPA - SINTEF ENERGI AS - FUNDACION TECNALIA RESEARCH & INNOVATION - TECHNISCHE UNIVERSITEIT DELFT - UNIVERSITY OF STRATHCLYDE - Teknologian tutkimuskeskus VTT Oy - - - EUR 9 999 987 - - - European Research Infrastructure supporting Smart Grid Systems Technology Development, Validation and Roll Out - - - EUR 9 999 987 - - - Austria - France - Greece - Germany - Netherlands - Netherlands - Denmark - Italy - Italy - France - Greece - Germany - Spain - Germany - Italy - Norway - Spain - Netherlands - United Kingdom - Finland - - - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - Renewable energy sources are key enablers to decrease greenhouse gas emissions and to cope with the anthropogenic global warming. The intermittent behaviour of them and their limited storage capabilities present new challenges - to power system operators in maintaining power quality and reliability. However, the increased availability of advanced automation and communication technologies has also provided new intelligent solutions to these challenges. Previous work has - presented various new methods to operate highly interconnected power grids with corresponding components in a more effective way. As a consequence of these developments the traditional power system is transformed into a cyber-physical system, a Smart - Grid. Previous and ongoing research activities have mainly focused on validating certain aspects of Smart Grids, but until now no integrated approach for analysing and evaluating complex configurations in a cyber-physical systems manner is available. - - - 2020-04-30, ongoing project | - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.2."> - - - INFRAIA-1-2014-2015 - Integrating and opening existing national and regional research infrastructures of European interest - - - RIA - Research and Innovation action - - - Austria - - - ERIGrid - - - H2020-INFRAIA-2014-2015 - - - 654113 - - - - - UNIVERSITA DEGLI STUDI DI PARMA - HELSINGIN YLIOPISTO - ITA-SUOMEN YLIOPISTO - LATVIJAS ORGANISKAS SINTEZES INSTITUTS - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - UNIVERZA V LJUBLJANI - TAROS CHEMICALS GMBH & CO KG - UNIVERSITEIT ANTWERPEN - APTUIT (VERONA) SRL - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - - - EUR 2 793 330,72 - - - Interdisciplinary Training Network for Validation of Gram-Negative Antibacterial Targets - - - EUR 2 793 330,72 - - - Italy - Finland - Finland - Latvia - United Kingdom - Slovenia - Germany - Belgium - Italy - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - - Antimicrobial resistance is posing a continuously-rising threat to global health. Indeed, one key recommendation from the recent “Action plan against the rising threats from Antimicrobial Resistance” report (submitted by the - Commission to the European Parliament and Council (15.11.2011)) is the development of effective antimicrobials or alternatives for treatment of human and animal infections. The INTEGRATE project is a direct response to this. We have assembled a team - of 10 beneficiaries from eight EU member states, encompassing both academic and non-academic sectors and different disciplines, to form a consortium committed to training Early Stage Researchers (ESRs) in the discovery and preclinical validation of - novel Gram-negative antibacterial agents and antibacterial targets. The principle aim of the consortium is to provide a training platform where students are exposed to every aspect of the antimicrobial discovery process, ranging from target - identification and validation, through organic synthesis, in silico design and compound screening, to mode-of-action and possible resistance mechanisms. This exposure will be accomplished through a concrete secondment plan, coupled with a series of - high-level consortium-wide training events and networking programmes. Our intention is to reverse the current fragmentation of approaches towards antibacterial discovery through mutual cooperation. The INTEGRATE training framework is built on an - innovative research project aimed at targeting important but non-essential gene products as an effective means of reducing bacterial fitness, thereby facilitating clearance of the pathogen by the host immune system. To achieve this, the individual - work programmes have been designed to seamlessly inter-mesh contributions from the fields of in silico design, organic synthesis, molecular biology and biochemistry, and the very latest in vitro and in vivo screening technologies. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Italy - - - INTEGRATE - - - H2020-MSCA-ITN-2014 - - - 642620 - - - - - UNIVERSIDAD DE NAVARRA - THE UNIVERSITY OF EDINBURGH - ADURO BIOTECH EUROPE BV - FUNDACION PARA LA INVESTIGACION MEDICA APLICADA FIMA - - - EUR 1 279 782,36 - - - Training Network for the education of the next generation scientist in targeting the supressive capacity of regulatory T-cells specifically within tumours - - - EUR 1 279 782,36 - - - Spain - United Kingdom - Netherlands - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - - Tumour immune-therapy has made dramatic improvements in recent years, saving the lives of cancer patients who just a few years ago would have been considered untreatable. It thereby became apparent that one specific type of - immune cell, so called regulatory T-cells, critically hampers the efficacy of tumour immune-therapy. Tumours, however, attract and exploit the immune-regulatory function of Tregs to dampen local immune responses and to induce local tolerance. - - 2022-05-31, Grant Agreement signed - - - 2018-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-EID - European Industrial Doctorates - - - Spain - - - Tumor-Treg-Targeting - - - H2020-MSCA-ITN-2017 - - - 765394 - - - - - UNIVERSITY OF SURREY - INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE - THE UNIVERSITY OF EDINBURGH - TECHNISCHE UNIVERSITAET MUENCHEN - INSTITOUTO TECHNOLOGIAS YPOLOGISTONKAI EKDOSEON DIOFANTOS - INSTITUTO DE TELECOMUNICACOES - TTY-SAATIO - NOISELESS IMAGING OY - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - - - EUR 3 866 329,44 - - - Machine Sensing Training Network - - - EUR 3 866 329,44 - - - United Kingdom - France - United Kingdom - Germany - Greece - Portugal - Finland - Finland - Germany - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - - The aim of this Innovative Training Network is to train a new generation of creative, entrepreneurial and innovative early-stage researchers (ESRs) in the research area of measurement and estimation of signals using knowledge - or data about the underlying structure. With its combination of ideas from machine learning and sensing, we refer to this research topic as “Machine Sensing”. We will train all ESRs in research skills needed to obtain an internationally-recognized - PhD; to experience applying their research a non-Academic sector; and to gain transferrable skills such as entrepreneurship and communication skills. We will further encourage an open “reproducible research” approach to research, through open - publication of research papers, data and software, and foster an entrepreneurial and innovation-oriented attitude through exposure to SME and spin-out Partners in the network. In the research we undertake, we will go beyond the current, and hugely - popular, sparse representation and compressed sensing approaches, to develop new signal models and sensing paradigms. These will include those based on new structures, nonlinear models, and physical models, while at the same time finding - computationally efficient methods to perform this processing. We will develop new robust and efficient Machine Sensing theory and algorithms, together methods for a wide range of signals, including: advanced brain imaging; inverse imaging problems; - audio and music signals; and non-traditional signals such as signals on graphs. We will apply these methods to real-world problems, through work with non-Academic partners, and disseminate the results of this research to a wide range of academic and - non-academic audiences, including through publications, data, software and public engagement events. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - MacSeNet - - - H2020-MSCA-ITN-2014 - - - 642685 - - - - - KURATORIUM FUER VERKEHRSSICHERHEIT - "HELLENIC RESEARCH AND EDUCATIONAL INSTITUTE ""PANOS MYLONAS"" FOR THE ROAD SAFETY AND THE PREVENTION/REDUCTION OF TRAFFIC ACCIDENTS" - TALLINNA TEHNIKAULIKOOL - CO-PLAN INSTITUTI PER ZHVILLIMIN EHABIITATIT - MIDDLE EAST TECHNICAL UNIVERSITY - SUOMALAINEN LIIKENNETUTKIMUSKESKUS OY - UNIVERSITETI POLIS SHPK - STICHTING WETENSCHAPPELIJK ONDERZOEK VERKEERSVEILIGHEID - TELECOMMUNICATION AND COMPUTER NETWORKING TNC SHPK - TECHNISCHE UNIVERSITAET WIEN - - - EUR 499 500 - - - Traffic Safety Cultures and the Safe Systems Approach – Towards a Cultural Change Research and Innovation Agenda for Road Safety - - - EUR 499 500 - - - Austria - Greece - Estonia - Albania - Turkey - Finland - Albania - Netherlands - Albania - Austria - - - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Other - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - Traffic Safety Culture (TraSaCu) aims at developing a cultural approach in road traffic safety research and accident prevention. Traditional approaches to traffic safety shall be complemented by a cultural perspective which - has emerged recently in safety research and prevention. Safety culture has been identified as an important factor of road safety as it helps understanding and explaining the typical patterns of risk perception and risk taking that prevail in - different national, regional or local traffic systems as well as their relationships with numbers and forms of accidents. A weak safety culture produce higher numbers of accidents which are more severe. A strong safety culture helps reducing the - number of accidents as well as mitigating their severity. It strengthens safety relevant attitudes and behaviour and it is also a condition for making road safety measures more effective. - - 2018-02-28, ongoing project - - - 2015-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Austria - - - TraSaCu - - - H2020-MSCA-RISE-2014 - - - 645690 - - - - - HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF EV - CHALMERS TEKNISKA HOEGSKOLA AB - TECHNISCHE UNIVERSITEIT DELFT - INSTITUT NATIONAL POLYTECHNIQUE DE TOULOUSE - KARLSRUHER INSTITUT FUER TECHNOLOGIE - LAPPEENRANNAN TEKNILLINEN YLIOPISTO - TECHNICKA UNIVERZITA V LIBERCI - POLITECHNIKA LODZKA - UNIVERSITY OF BATH - ITA-SUOMEN YLIOPISTO - - - EUR 3 819 642,12 - - - Smart tomographic sensors for advanced industrial process control - - - EUR 3 819 642,12 - - - Germany - Sweden - Netherlands - France - Germany - Finland - Czech Republic - Poland - United Kingdom - Finland - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - A decisive gap in the process industry is the lack of qualified distributed process parameter measurements for optimal control. Process tomography is a ground-breaking technology to bridge this gap. Just with the recent - development in high-power massive parallel computing this technology has gained the required real-time capability. TOMOCON as a European network of leading academic and industrial partners from different sectors dedicates its efforts in research and - training towards development of tomography-based industrial process control. With that it shall generate new scientific and technical knowledge in this emerging field; develop and demonstrate new technological solutions of advanced industrial control - by tomographic sensors; align tomography-based process control with concepts of knowledge-based control, big data analysis and advanced human-machine interfaces; and enhance the scientific and transferable skills of early stage researchers to meet - future needs of the industry. Together with world-leading industrial sensor and control solution providers, process engineering and production companies TOMOCON shall demonstrate the functionality of tomography-assisted process control in four - industry-relevant demonstration cases, which serve as benchmarks to demonstrate improvements in energy and resource efficiency as well as product quality. That is: control of inline fluid separation, control of microwave drying processes, control of - continuous metal casting, and control of batch crystallization processes. - - 2021-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - TOMOCON - - - H2020-MSCA-ITN-2017 - - - 764902 - - - - - UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA - TOYOTA MOTOR EUROPE - - - EUR 743 618,88 - - - European Industrial Doctorate in Innovative POLYmers for Lithium Battery TEchnologies - - - EUR 743 618,88 - - - Spain - Belgium - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - POLYTE-EID European Industrial Doctorate will offer excellent training opportunities to 3 Early Stage Researchers in the area of Polymers for Electrochemical Energy Storage. POLYTE-EID puts together the expertise in batteries - for automotive of Toyota Motor Europe (TME) with the academic excellence in polymers of the University of the Basque Country (POLYMAT). The final objective is to train scientists who may face some of the upcoming European energy and transportation - challenges. The project proposal is a well-balanced combination of fundamental material&polymer science with applied research in electrochemical energy storage technologies. The project will search the development of new polymeric materials to - increase the performance and security of actual and future batteries. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-EID - European Industrial Doctorates - - - Spain - - - POLYTE - - - H2020-MSCA-ITN-2017 - - - 765828 - - - - - DANMARKS TEKNISKE UNIVERSITET - TECHNISCHE UNIVERSITAET WIEN - MAELARDALENS HOEGSKOLA - TECHNISCHE UNIVERSITAET KAISERSLAUTERN - TTTECH COMPUTERTECHNIK AG - SYSGO AG - ABB AB - - - EUR 4 000 793,40 - - - Fog Computing for Robotics and Industrial Automation - - - EUR 4 000 793,40 - - - Denmark - Austria - Sweden - Germany - Austria - Germany - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - We are at the beginning of a new industrial revolution (Industry 4.0): disruptive technologies such as cyber-physical systems, machine-to-machine communication, Big Data and machine learning, and human-robot collaboration will - transform the manufacturing and industrial automation sectors. However, Industry 4.0 will only become a reality through the convergence of Operational and Information Technologies (OT & IT). The European Parliament, says that “a very wide range - of skills is required for [Industry 4.0] implementation. […] the convergence of IT, manufacturing, automation technology and software requires the development of a fundamentally new approach to training IT experts.” The FORA interdisciplinary, - international, intersectoral network will train the next generation of researchers to lead this convergence and cross the IT-OT gap. The convergence will be achieved through the new concept of Fog Computing, which is a logical extension from Cloud - Computing towards the edge of the network (where machines are located), enabling applications that demand guarantees in safety, security, and real-time behavior. Research objectives focus on: a reference system architecture for Fog Computing; - resource management mechanisms and middleware for deploying mixed-criticality applications in the Fog; safety and security assurance; service-oriented application modeling and real-time machine learning. Our ambitious objectives require individuals - with a unique combination of interdisciplinary and intersectoral skills. Thus, FORA’s 15 ESRs will receive integrated training across key areas (computer science, electrical engineering, control engineering, industrial automation, applied mathematics - and data science) necessary to fully realize the potential of Fog Computing for Industry 4.0 and will move between academic and industrial environments to promote interdisciplinary and intersectoral learning. - - 2021-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Denmark - - - FORA - - - H2020-MSCA-ITN-2017 - - - 764785 - - - - - CENTRE INTERNACIONAL DE METODES NUMERICS EN ENGINYERIA - UNIVERSITA DEGLI STUDI DI PAVIA - SWANSEA UNIVERSITY - TECHNISCHE UNIVERSITAET MUENCHEN - ECOLE CENTRALE DE NANTES - INSTITUTO SUPERIOR TECNICO - UNIVERSITE LIBRE DE BRUXELLES - TECHNISCHE UNIVERSITEIT EINDHOVEN - - - EUR 3 831 509,88 - - - Industrial decision-making on complex production technologies supported by simulation-based engineering - - - EUR 3 831 509,88 - - - Spain - Italy - United Kingdom - Germany - France - Portugal - Belgium - Netherlands - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Simulation-based engineering (SBE), in which traditional R&D, design and production technologies are complemented with computer simulations, has revolutionized the industrial sector. Computer simulations are critical for - control of manufacturing processes, non-destructive-testing and decision-making at production phases, and shorten the lead-time of design and development processes, thus reducing both costs and time-to-market. - - - 2022-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-EJD - European Joint Doctorates - - - Spain - - - ProTechTion - - - H2020-MSCA-ITN-2017 - - - 764636 - - - - - Fundacion IMDEA Energia - NORTHWESTERN UNIVERSITY - - - EUR 239 191,20 - - - Solar Energy Storage PERovskites - - - EUR 239 191,20 - - - Spain - United States - - - Research Organisations - Higher or Secondary Education Establishments - - Solar energy, attractive source of energy being it free and endless, can be converted into electricity by means of a Concentrating Solar Power (CSP) plant. However, the biggest limit of such technology is the intermittency and - the diurnal nature of the solar light. For their future development, CSP plants need to be coupled with storage system. Among the existing thermal storage systems, the ThermoChemical Storage (TCS) is one of the most promising technology and it is - based on the exploitation of the reaction heat of a reversible chemical reaction. Just recently, perovskite systems have drawn increasing interest as promising candidates for TCS systems. Perovskites are generally indicated as ABO3, with A and B the - two cations of the structure and with O the oxygen. They exhibit a continuous, quasi-linear oxygen release/uptake within a very wide temperature range. Their reduction being endothermic consists in the heat storage step, while the exothermic - oxidation releases heat when it is required. The overall objective of the proposal is to study more earth abundant compositions (Ca-, Fe-, Mn- or Co-based) of perovskites for identifying one or more promising candidate storage medium for the design - and the realization of a prototype of a multilevel-cascaded TCS system. It aims at solving the no-easy solution problem of the wide temperature range to be covered by a TCS system for CSP plant by using perovskites with different operating - temperatures cascaded from the lowest operating temperature to the maximum one. As main result it could bring the TCS systems to a level closer to the market scale. The research project will be developed in collaboration with the IMDEA Energy - Institute and the Materials Science and Engineering Department of Northwestern University. This project idea is totally in line with the current strict global energy and environmental politics and also with the Horizon 2020 objectives. - - 2020-11-12, ongoing project - - - 2017-11-13 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Spain - - - SESPer - - - H2020-MSCA-IF-2016 - - - 746167 - - - - - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - - - EUR 171 460,80 - - - A mature Quokka for everyone – advancing the capabilities and accessibility of numerical solar cell simulations - - - EUR 171 460,80 - - - Germany - - - Research Organisations - - This project is placed in the field of photovoltaics (PV), which is on the eve of competing with conventional electricity generation on a purely economic basis, and is able to effectively tackle ecologic and socio-economic - problems caused by the existing energy system based on fossil fuels. - - 2018-01-31, closed project - - - 2016-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - Quokka Maturation - - - H2020-MSCA-IF-2014 - - - 655852 - - - - - TECHNISCHE UNIVERSITAET WIEN - - - EUR 166 156,80 - - - BioNetIllustration: User centric illustrations of biological networks - - - EUR 166 156,80 - - - Austria - - - Higher or Secondary Education Establishments - - In living systems, one molecule is commonly involved in several distinct physiological functions. The roles of molecules are commonly summarized in pathway diagrams, which, however, are abstract, hierarchically nested and thus - is difficult to comprehend especially by non-expert audience. The primary goal of this research in visualization is to intuitively support the comprehensive understanding of relationships among biological networks using interactively computed - illustrations. Illustrations, especially in textbooks of biology are carefully designed to clearly present reactions between organs as well as interactions within cells. Automatic generation of illustrative visualizations of biological networks is - thus the technical content of this proposal. Automatic generation of hand-drawn illustrations has been a challenging task due to the difficulty of algorithmically describing a human creative process such as evaluating and selecting significant - information and composing meaningful explanations in a visually plausible manner. Our high-level idea in BioNetIllustration is to simulate this process by decomposing the entire problem into multiple steps including content-driven layout and - illustration design as well as spatio-temporal event transitions across multiple representations. As a pioneer study on illustrations, a new visualization framework for these network illustrations will be developed. This study can be achieved by - matching the unique competences of the researcher and the host research group and allows an innovative synthesis to produce hand-drawn like illustrations of biological networks. The project also involves experts from several disciplines including - network and medical visualization, data mining, systems biology as well as perceptual psychology. The result will provide a new direction for physiological process analysis and accelerate the knowledge transfer not only within experts but also to the - public. - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Austria - - - BioNetIllustration - - - H2020-MSCA-IF-2016 - - - 747985 - - - - - TTY-SAATIO - SVEUCILISTE U ZAGREBU FAKULTET ELEKTROTEHNIKE I RACUNARSTVA - UNIVERSITA DEGLI STUDI ROMA TRE - NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU - MAELARDALENS HOEGSKOLA - LEONARDO - SOCIETA PER AZIONI - CROSSCONTROL AB - XYLON DOO - BENEQ OY - - - EUR 3 957 576,84 - - - Immersive Visual Technologies for Safety-critical Applications - - - EUR 3 957 576,84 - - - Finland - Croatia - Italy - Norway - Sweden - Italy - Sweden - Croatia - Finland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - In many contexts – heavy work machines, emergency response, control centres – human operators face complex and demanding situations where their decisions can have far-reaching consequences on productivity, environment, and - even human lives. In order to deal with such challenges, the operator needs full situational awareness, which can be achieved by sensing relevant visual data about the operating environment, refining it into mission-critical information, and - presenting it in an immersive, intuitively comprehensible manner. This can be achieved by Immersive Visual Technologies (IVT) delivering ultra-realistic and interactive visual experience. - - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Finland - - - ImmerSAFE - - - H2020-MSCA-ITN-2017 - - - 764951 - - - - - TTY-SAATIO - UNIVERSITEIT MAASTRICHT - KEMIRA OYJ - KUNGLIGA TEKNISKA HOEGSKOLAN - KATHOLIEKE UNIVERSITEIT LEUVEN - PREDILNICA LITIJA DOO - TECHNISCHE UNIVERSITAET GRAZ - UNIVERZA V MARIBORU - - - EUR 3 832 629,48 - - - A Training Network on Designing Novel Bio-based Fibre Products for Targeted Advanced Properties and New Applications - - - EUR 3 832 629,48 - - - Finland - Netherlands - Finland - Sweden - Belgium - Slovenia - Austria - Slovenia - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - FibreNet will train young fibre-professionals having multidisciplinary view to develop sustainable bio-based fibre products with tailored properties for different application fields in both academic and non-academic sectors. - Bio-based fibre products are one of the corner-stones in the European bio-based industry corresponding to 12% of the employment in manufacturing. The industry, including such sectors as packaging, paper, biocomposites and biomedical and hygienic - textiles, is currently undergoing a fundamental transformation in order to respond to the competition raised i) by low-wage countries and ii) by fossil-based materials. A common consensus in Europe is that to remain competitive and sustain the - bio-based fibre industries in Europe, we should focus on developing new high added value products that have specific functionalities but reduced environmental impacts. - - 2021-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Finland - - - FibreNet - - - H2020-MSCA-ITN-2017 - - - 764713 - - - - - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - LOUGHBOROUGH UNIVERSITY - UNIVERZA V LJUBLJANI - FUNDACION CENER-CIEMAT - POLYMER COMPETENCE CENTER LEOBEN GMBH - ACCADEMIA EUROPEA DI BOLZANO - ELECTRICITE DE FRANCE - KENERGIA SVILUPPO SRL - - - EUR 3 576 247,56 - - - Photovoltaic module life time forecast and evaluation - - - EUR 3 576 247,56 - - - Germany - United Kingdom - Slovenia - Spain - Austria - Italy - France - Italy - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The quality assurance in the photovoltaic industry is yet in its infancy, requiring both underpinning science and trained personnel to reduce costs of energy. An unmet industrial requirement is an accelerated, and operating - environment specific, service life time and energy yield assessment. SOLAR-TRAIN will qualify ESRs in the field of PV durability as part of a highly innovative, multi-disciplinary project meeting industry requirements. The objective is to develop - novel, validated models for the service life time and energy prediction of PV modules and systems. The elements to this puzzle are researched in the frame of 14 PhD projects with individual areas of focus, such as (a) climatic degradation factors, - (b) system analytics, (c) material (polymer) parameters, (d) service life & energy models, (e) linking production to performance and (f) performance enhancement by improved O&M. Commercial and test samples will be produced and tested in the - distributed measurement campaign during this project. They will be exposed to state-of-the-art and to-be-developed stress cycles to allow a validated link of degradation to stresses, production methods, materials and methods of deployment. - Accelerated and lower cost test cycles for the assessment of innovative materials and module developments will be delivered. The project is integrated both in terms of research as well as training. This inter-sectoral approach provides excellent - theoretical and technical background as well as immersion in different business sectors and career mentoring, allowing ESRs to build up a sustainable professional network across Europe. For a most effective cross-sectoral training, the project’s - beneficiaries and partners represent the entire value chain, from materials developers / manufacturers through to operators and insurance companies. SOLAR-TRAIN will deliver on the targets stated in Issue Paper No. 2 of the SET Plan to maintain and - strengthen PV leadership in Europe. - - 2020-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - SOLAR-TRAIN - - - H2020-MSCA-ITN-2016 - - - 721452 - - - - - PARTNERSHIP FOR ADVANCED COMPUTINGIN EUROPE AISBL - EUROPEAN TECHNOLOGY PLATFORM FOR HIGH PERFORMANCE COMPUTING - - - EUR 2 551 875 - - - European eXtreme Data and Computing Initiative - - - EUR 2 551 875 - - - Belgium - Netherlands - - - Other - Other - - The three most significant HPC bodies in Europe, PRACE, ETP4HPC and EESI, have come together within EXDCI to coordinate the strategy of the European HPC Ecosystem in order to deliver its objectives. In particular, the project - will harmonize the road-mapping and performance monitoring activities of the ecosystem to produce tools for coherent strategy-making and its implementation by: - - 2018-02-28, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.2."> - - - FETHPC-2-2014 - HPC Ecosystem Development - - - CSA - Coordination and support action - - - Belgium - - - EXDCI - - - H2020-FETHPC-2014 - - - 671558 - - - - - UNIVERSITA DEGLI STUDI DI PERUGIA - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - KAUNO TECHNOLOGIJOS UNIVERSITETAS - KATHOLIEKE UNIVERSITEIT LEUVEN - UNIVERSITE DE NANTES - UNIVERSITY OF NEWCASTLE UPON TYNE - Research Center for Non Destructive Testing GmbH - TWI LIMITED - THE UNIVERSITY OF WARWICK - BRUSSELS AIRLINES - - - EUR 3 808 670,04 - - - NDTonAIR: Training Network in Non-Destructive Testing and Structural Health Monitoring ofAircraft structures - - - EUR 3 808 670,04 - - - Italy - France - Germany - Lithuania - Belgium - France - United Kingdom - Austria - United Kingdom - United Kingdom - Belgium - - - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The “NDTonAIR” consortium involves Universities, Research Organisations and major European companies working on new Non-Destructive Testing (NDT) and Structural Health Monitoring (SHM) techniques for aerospace, of which both - are key technologies. The goal is to train a new generation of scientists and engineers with a wide background of theoretical and experimental skills, capable of developing their research and entrepreneurial activities both in academy and industry - and playing an active role in promoting the importance of quality inspection and structural monitoring in aerospace components. - - - 2020-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Italy - - - NDTonAIR - - - H2020-MSCA-ITN-2016 - - - 722134 - - - - - STICHTING KATHOLIEKE UNIVERSITEIT - STICHTING KATHOLIEKE UNIVERSITEIT - - - EUR 150 000 - - - Commercialising a novel diagnostic panel for patient stratification in Age-related MACULAr Degeneration - - - EUR 150 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In MACULA2 we aim to develop a genetic diagnostic test for complement activation that will allow proper stratification of patients with age-related macular degeneration (AMD). AMD is an inflammatory disease, the #1 cause of - blindness in the world, with 196 million patients estimated for 2020. Such a test does not currently exist, strongly hampering drug development and patient treatment. Poor patient stratification contributes to high failure rates in trials for AMD. - Local and systemic inflammation in AMD are caused by deregulated activation of the alternative pathway of the complement system. In AMD, some patients have higher complement activation levels compared to controls, which stimulates further - inflammation. Several complement-lowering therapies for AMD are under development. Pharmaceutical companies are aware that patients with a genetic predisposition to higher complement activation levels will potentially benefit most from such - treatments. Without sound patient stratification, therapies that are currently in clinical trials may not reach the statistical significance needed for approval. However, certain individuals might actually benefit from these therapies because of - their specific genetic makeup. We aim to solve the challenge of patient stratification in AMD by developing a novel diagnostic test based on genetic testing combined with a patient questionnaire. An AMD diagnostic test will contribute towards a - precision medicine approach towards treatment of patients. - - 2019-05-31, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Netherlands - - - MACULA2 - - - ERC-2016-PoC - - - 737607 - - - - - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - - - EUR 183 454,80 - - - How single DNA polymerases make decisions during proofreading - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - DNA polymerases (DNA Pols) make various decisions during DNA replication. Decisions regarding nucleotide selection, lesion bypass and how to respond to replication errors are a few important examples. During replication, DNA - Pols can synthesize DNA at remarkable rates, e.g. 1,000 bp/s for E. Coli DNA Pol III. However, errors can be introduced during replication, resulting in a terminal DNA mismatch. Mismatches can then be sensed and removed by action of the 3’ to 5’ - exonuclease activity of the DNA Pol. How DNA Pols can sense mismatches to initiate proofreading and how the primer strand migrates into the exonuclease domain, often a distance of 30 Å, is the focus of this proposal. Moreover, this research aims to - understand mechanisms of proofreading in higher complexity DNA Pol assemblies at single-molecule resolution. Proofreading will be studied with the model enzyme E. Coli DNA Pol III, consisting of separate protein subunits that assemble to form a - higher order complex, namely the polymerase, exonuclease and the β2-clamp, which is a processivity factor that encircles the DNA and increases the affinity of the polymerase to the DNA. The proposed work will employ single-molecule FRET in order to - evaluate proofreading dynamics at high spatial and temporal resolution. Three main objectives will be performed in order to understand (1) how DNA mismatches initiate proofreading (2) how mutations within the exonuclease domain affect proofreading - and (3) how DNA lesions can influence proofreading as a function of position within the DNA template. These objectives will be achieved with a single-molecule FRET assay containing fluorescently labelled DNA to monitor proofreading dynamics in real - time. This work will shift the knowledge frontier by advancing our understanding of proofreading during DNA replication in order to better realise the relationship between DNA mutations and the development of human diseases like cancer. - - 2018-03-31, Grant Agreement terminated - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - DNA Pol III - - - H2020-MSCA-IF-2015 - - - 705015 - - - - - UNIVERSIDAD DE ZARAGOZA - UNIVERSITEIT GENT - ASTON UNIVERSITY - UNIVERSITAET HOHENHEIM - STOCKHOLMS UNIVERSITET - QUEEN MARY UNIVERSITY OF LONDON - THE UNIVERSITY OF EDINBURGH - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - ORGANICS LIMITED - AVA GREEN CHEMISTRY DEVELOPMENT GMBH - - - EUR 3 623 830,56 - - - Advanced Carbon Materials from Biowaste: Sustainable Pathways to Drive Innovative Green Technologies - - - EUR 3 623 830,56 - - - Spain - Belgium - United Kingdom - Germany - Sweden - United Kingdom - United Kingdom - Germany - United Kingdom - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The energy crisis, environmental pollution and global warming are serious problems that are of great concern throughout the world. Around 40% of the world’s energy consumption is dedicated to the production of materials and - chemicals. Thus, there is a need to develop high-performance materials based on renewable resources, simpler to synthesise and cost effective. Carbon materials derived from renewable resources (e.g., biomass) are ideal candidates to meet these needs. - The main objective of our proposed Innovative Training Network is to develop new scientific knowledge, capability, technology, and commercial products for biomass-derived carbons (BCs); thus impacting the way that Europe uses and innovates with - sustainable carbon materials. This will be accomplished through outstanding research and training programmes for fourteen early-stage researchers (ESRs). Our proposed research programme is feasible given the varied expertise and knowledge of the - academic and industrial participants. We expect that GreenCarbon will improve our ability to rationally design a range of functionalised BC-derived materials using different individual and synergistically coupled processes and expand their practical - applications. Our research programme comprehensively covers all aspects from precursors (the nature of biomass) to processing (thermochemical conversion, porosity development, chemical functionalisation) and application (e.g., CO2 capture, - heterogeneous catalysis and chemicals from biomass) enabling a unique design of engineered sustainable BC materials. At the same time, our training programme is designed with the aim to empower the ESRs through the provision of a comprehensive and - coherent training package, which includes complementary competencies and knowledge in all the science, engineering and business skills so as to be capable of deploying new technologies within different environments both inside and outside of - academia. - - 2020-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Spain - - - GreenCarbon - - - H2020-MSCA-ITN-2016 - - - 721991 - - - - - KAROLINSKA INSTITUTET - - - EUR 173 857,20 - - - A multifunctional self-immolative hydrogel for accelerating the healing of chronic wounds - - - EUR 173 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - In this Marie Skłodowska-Curie Fellowship project entitled “Multi-SIP Hydrogel” I will design a modular synthetic platform for preparing multifunctional self-immolative polymer (SIP) hydrogels designed to accelerate tissue - regeneration in chronic skin wounds. The hydrogels will contain multiple SIP components, each designed to rapidly degrade and deliver a therapeutic payload in response to a specific biochemical stimulus typical of a chronic wound (e.g., reactive - oxygen species or enzymatic action). During the two years of this Fellowship, I aim to establish a proof-of-principle SIP-hydrogel system that will undergo sequential stimuli-responsive degradation and promote cell proliferation in vitro. This - Fellowship will be undertaken under the supervision of Prof. Molly Stevens in the Division of Biomaterials and Regenerative Medicine at the Karolinska Institute (KI), which has the world-leading expertise in polymer chemistry, biomaterials - engineering, cell biology and tissue engineering crucial to the objectives of the proposed work plan. Due to the modular design of the "Multi-SIP Hydrogel" platform, there is broad scope for designing SIP-hydrogels matched to different tissue types - once a proof-of-principle is established. This will initiate new research areas at the cutting edge of biomaterials science, which will help me to establish my own independent research career following the proposed Fellowship. - - 2019-01-31, ongoing project - - - 2017-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - Multi-SIP Hydrogel - - - H2020-MSCA-IF-2015 - - - 705475 - - - - - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - - - EUR 195 454,80 - - - Towards a Reliable Model for Dark Matter Search Experiments - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - There is ample evidence that our Milky Way is embedded in a halo of Dark Matter. While the sun is revolving around the galactic center, it moves through this halo resulting in a constant Dark Matter wind on earth. The - revolution of the earth around the sun produces then an annual modulation of the intensity of this wind. Dark Matter detection experiments have produced contradicting results so far. While the DAMA/LIBRA experiment reports the measurement of an - annual modulation consistent with a Dark Matter signal, other experiments have not seen an interaction so far. The SABRE experiment aims to shed light on this controversy by detecting the annual modulation in the same target material as DAMA but with - improved the sensitivity and using twin detectors in the northern and southern hemispheres. SABRE is currently preparing for a proof of principle at the same underground laboratory in Italy where DAMA operates, and will upgrade afterwards to the - full-scale experiment. - - 2018-06-30, Grant Agreement terminated - - - 2016-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SABRE - - - H2020-MSCA-IF-2015 - - - 703650 - - - - - UNIVERSIDAD COMPLUTENSE DE MADRID - - - EUR 158 121,60 - - - Ireland and Late-Georgian British Imaginings of Belonging: With Particular Reference to William Wordsworth - - - EUR 158 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - Belonging – a concept at the heart of which lies a yearning for home – has domestic, regional, national, and even cosmopolitan implications. It was a particularly important concept in late-Georgian Britain (c. 1780-1830), - during which time socio-political instabilities fostered an inward-looking impetus, prompting Britons to ask what home meant and what attachment to home entailed. - - 2019-09-14, Grant Agreement terminated - - - 2017-09-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - ILBIB - - - H2020-MSCA-IF-2016 - - - 749888 - - - - - THE UNIVERSITY OF BIRMINGHAM - STICHTING KATHOLIEKE UNIVERSITEIT - - - EUR 165 598,80 - - - Large-scale cortical communication: Brain oscillatory mechanisms of attention allocation and selective inhibition - - - EUR 165 599,30 - - - United Kingdom - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This research proposal aims to identify basic mechanisms of local and global communication within the human brain enabling dynamic information processing. Specifically, I will investigate how the human brain allocates - cognitive resources (via selective attention and inhibition) and therefore, dynamically engages and disengages frontal and posterior cortical areas. Several oscillatory mechanisms have been proposed to orchestrate such local and global cortical - communication. While there are theoretical models hypothesising such mechanisms (i.e. gating by inhibition and cognitive resource allocation), to date no systematic empirical investigation of the interaction between these mechanisms exists. The - current proposal aims at filling this gap by investigating the interaction – and the complexity thereof – between the neuronal mechanisms of different cognitive operations when they need to be integrated. The results will therefore serve to establish - a common framework that links individual mechanisms and maps their interactions in the human brain. - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - BrainCrossTalk - - - H2020-MSCA-IF-2015 - - - 703456 - - - - - UNIVERSITEIT GENT - TECHNISCHE UNIVERSITEIT DELFT - RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN - VYSOKA SKOLA CHEMICKO-TECHNOLOGICKA V PRAZE - UNIVERSITAT POLITECNICA DE CATALUNYA - - - EUR 3 715 183,44 - - - Sustainable Product, Energy and Resource Recovery from Wastewater - - - EUR 3 715 183,44 - - - Belgium - Netherlands - Germany - Czech Republic - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In many cases energy, water and resources contained in wastewater may have significant value if recovered. Therefore, the EU is currently confronted with a paradigm shift from wastewater treatment to resource recovery. To - facilitate this shift, the SuPER-W European Joint Doctorate programme trains early-stage researchers (ESRs) in developing technologies for water, energy, nutrient and metal reuse, and bioproduction from (waste)water. The ESRs obtain knowledge and - skills needed to turn environmental problems into economic opportunities. SuPER-W focuses not only on technology development through research, but the ESRs are also trained in translating research into policy, creative problem-solving, identification - of bottlenecks for effective implementation of resource recovery technologies, development of business cases and urban/industrial ecosystems, and assessment of sustainability and the role of public perception and policy in innovation. Furthermore, - they acquire a set of commercial, entrepreneurial and managerial skills that prepare them as future leaders. All ESRs are supervised by at least 2 promoters from 2 universities and co-supervised by a researcher from a non-academic partner - organisation. Moreover, they conduct an internship in the non-academic sector in the first and last project year, contributing to more effective dissemination and exploitation of their research results. To organise the training, SuPER-W brings - together leading researchers from 5 renowned universities and 12 associated non-academic partner organisations, including industrial partners involved in technology development, SMEs focused on consultancy/engineering, a service provider, a - government agency, and professional network organisations. ESRs who successfully defend the PhD thesis and finish the doctoral training programme receive a double or joint PhD degree, jointly awarded by the universities of his/her promoters, as well - as a joint doctoral training certificate of SuPER-W. - - 2020-02-29, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-EJD - Marie Skłodowska-Curie Innovative Training Networks (ITN-EJD) - - - MSCA-ITN-EJD - European Joint Doctorates - - - Belgium - - - SuPER-W - - - H2020-MSCA-ITN-2015 - - - 676070 - - - - - THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN - - - EUR 195 454,80 - - - Simple fusion systems and linking systems - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The classification of finite simple groups is often regarded as one of the major mathematical achievements of the 20th century. Its importance lies not only in the fundamental result, but also in the methodology and conceptual - framework developed for its proof. Most intriguingly, it turned out that the structure of a finite group is closely connected to the structure of the p-local subgroups, i.e. the normalizers of non-trivial p-subgroups, for a suitably chosen prime p. - Of particular importance is the prime 2. Even though the proof of the classification of finite simple groups is insightful in its major conceptual approach, it is extremely long and difficult in its details. Thus, it would be of great interest to - obtain a simplified proof. Moreover, to gain the maximum benefit from the methods of the proof of the classification, it is highly desirable to work in a more general context which in particular allows also for applications in the modular - representation theory of finite groups. Saturated fusion systems provide a conceptual framework for this and connect to important questions in homotopy theory. A program to find a new and better proof of the classification of finite simple groups - through a classification of simple fusion systems at the prime 2 has been recently outlined by Aschbacher. Two parts of our proposal concern classification problems for fusion systems. Their significance lies not only in completing important cases in - Aschbacher's program, but also in giving new insight into the relative abundance of exotic examples, i.e. fusion systems not induced by any finite group. In the third part we attack a major problem in the algebraic theory of fusion systems by - defining an analogue in fusion systems of centralizers of subgroups of finite groups. This will simultaneously facilitate a classification of fusion systems in the spirit of Aschbacher's program, and lead to a combinatorial understanding of maps - between classifying spaces of fusion systems. - - 2018-07-31, Grant Agreement terminated | - - - 2016-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - FusionSystems - - - H2020-MSCA-IF-2015 - - - 707758 - - - - - RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN - RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN - - - EUR 1 500 000 - - - Semiconductor-based quantum network - - - EUR 1 500 000 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Quantum networking would enable the connection of quantum processing nodes to increase computing power, long distance intrinsically secure communication, and the sharing of quantum resources over wide networks. Fully realizing - these prospects requires local nodes with many coupled qubits connected by photonic links. Currently, qubits with good prospects for scaling to large numbers provide no optical interface, while optically addressable systems appear difficult to scale. - This project aims to establish the fundamentals for quantum networks consisting of potentially scalable semiconductor spin qubits in gated GaAs quantum dots. These electrically controlled qubits have been proven viable for quantum computing, but so - far have not been interfaced coherently with photons. - - 2021-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - SEQUNET - - - ERC-2015-STG - - - 679342 - - - - - CRANFIELD UNIVERSITY - PANEPISTIMIO IOANNINON - UNIVERSITA DEGLI STUDI DELLA CAMPANIA LUIGI VANVITELLI - EXIS INNOVATION LTD - - - EUR 1 995 113 - - - An Innovative Method for Improving the Structural Integrity using SMA Revolutionary Technology - - - EUR 1 995 113 - - - United Kingdom - Greece - Italy - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The project proposes to develop a revolutionary coating that will be able to alter and control the mechanical properties of materials by external stimuli. This novel coating will be able to contribute to the stiffness and - rigidity of an elastic metallic structure, to withstand the expected loading conditions safely, to enhance the integrity of a damaged structure and at the same time to protect it from corrosion. Such coating can bring multiple breakthroughs from the - design level to the maintenance and repair level of the structure. The innovative compounds of the proposed coating are elements of smart materials - Shape Memory Alloys (SMAs). SMA elements are designed materials that have one or more properties - that can be significantly changed in a controlled fashion by external stimuli. They can sense temperatures or stress as a function of change in damping, stiffness, electrical resistivity and deflection. It is specifically the latter aspect, which - makes SMAs highly interesting for the particular application, since it is the actuation function built into the material. The innovative concept of the coating is described briefly as follows: upon mechanical loading the structure and hence the - coating are deformed together as a system. However, by heating the coating, the SMA elements tend to recover their experienced deformations and return to their original shape. At this point, shear forces will be developed to the interface between - coating and structure. The developed shear forces are expected to mitigate the deformation of the structure and reduce the level of the stress field. The latter is a great benefit for the regions, where cracks exist, since the local reduction of the - stress field will delay the crack propagation and hence the structural failure. Finally, the coating will be also followed by a system that will ensure a satisfactory cover of the metallic surface, as well as a module for assessing the effect of any - structural defects that may exist. - - 2018-06-30, ongoing project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-1-2014 - FET-Open research projects - - - RIA - Research and Innovation action - - - United Kingdom - - - InnoSMART - - - H2020-FETOPEN-2014-2015-RIA - - - 664892 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - THE UNIVERSITY OF EXETER - KOBENHAVNS UNIVERSITET - - - EUR 1 999 555 - - - The makeup of the modern horse: a history of the biological changes introduced by human management - - - EUR 1 999 555 - - - France - France - United Kingdom - Denmark - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The horse provided us with rapid transportation, an almost unrivaled secondary product that tremendously impacted the politico-economical trajectory of our societies, revolutionizing the circulation of ideas, people, - languages, religions and communication. Horse chariotry and cavalry also changed warfare and beyond the battlefield new equestrian technologies have stimulated agricultural productivity. However, the 5,500 year long history of horse domestication and - management, which transformed the natural evolutionary trajectory of wild horses into the more than 625 domestic breeds living today, is difficult to reconstruct from archaeology, history and modern genetics alone. Yet, with archaeogenetics, one can - access the genetic information from past individuals and track in great detail past population trajectories. In this project, I propose to build on the latest advances in the analysis of ancient DNA molecules to gather new genomic, epigenomic and - metagenomic information from ancient horses. This will be integrated with archaeozoological, isotopic and historical data to enhance our understanding of the multiple processes underlying the transformation of the animal that perhaps most impacted - our history. Starting from the characterization of pre-domestic populations of wild horses, I will evaluate the genomic and dietary impact of early domestication stages and will explore whether horses were independently domesticated in Iberia and the - Pontic-Caspian steppe. I will follow how the emergence of chariotry and the development of heavy cavalry impacted the horse’s behavioural, physiological and biological makeup. I will reveal the horse characteristics that were preferred in various - historical contexts and will investigate a diversity of management strategies and husbandry conditions to reveal their impact on horses, from classical and late antique periods until the recent creation of modern breeds by means of intensive - selective breeding. - - 2021-11-30, ongoing project - - - 2016-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - France - - - PEGASUS - - - ERC-2015-CoG - - - 681605 - - - - - RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN - RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN - - - EUR 2 499 884 - - - Multi-Scale Description of Non-Universal Behavior in Turbulent Combustion - - - EUR 2 499 884 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Combustion is an extremely important field for our society. The development of new, step-change technologies is essential and greatly benefits from computational design. However, turbulent combustion physics are complex, - highly non-linear, of multi-scale and multi-physics nature, and involve interactions at many time-scales. This makes modeling quite challenging such that accurate predictive models, especially for the formation of pollutants, are not available. - Today, the two major challenges for developing predictive simulations of turbulent combustion are first to account for its multi-scale nature by considering the non-universal behavior of small-scale turbulence, which is known to be critically - important for turbulence-chemistry interactions, and second, to provide data in sufficient detail for rigorous analysis of model deficiencies and unambiguous model development. These two issues are addressed in the proposed work. The main overall - objectives are: 1) Establish a new multi-scale framework to analyze and model turbulent combustion phenomena based on a new way to describe turbulence using so-called dissipation elements, which are space-filling regions in a scalar field allowing to - capture its small-scale morphology and non-universality. 2) Create new unprecedented datasets using direct numerical simulations (DNS) and provide new analysis methods to develop and validate combustion models; this will include automatically - reducing and optimizing chemical kinetic mechanisms for use in DNS and developing an on-the-fly chemistry reduction technique. 3) Apply new modeling approaches to complex and highly non-linear modeling questions, such as pollutant formation in - turbulent spray combustion. The successful outcome of the project will provide new and unprecedented datasets, a quantitative description of the impact of non-universality in small-scale turbulence on different aspects of turbulent combustion, and - the basis for an entirely new multi-scale closure. - - 2021-05-31, ongoing project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - MILESTONE - - - ERC-2015-AdG - - - 695747 - - - - - RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN - RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN - - - EUR 1 491 875 - - - Fundamental Studies in Catalysis – Reactivity Design with Experimental and Computational Tools - - - EUR 1 491 875 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Catalysis is ubiquitous in modern academic and industrial chemistry as well as an integral and indispensable discipline that may contribute to solutions of current global challenges. While the field has grown significantly - over the past few decades, with numerous transformations that were previously unthinkable now being possible, progress has frequently relied on serendipitous discoveries or elaborate screening efforts. Although it is indisputable that high-throughput - screening is an extremely lucrative approach to generate a wealth of chemical information, the next frontier in the development of innovative approaches to meet the high demand for predictable, selective and sustainable processes will likely arise - from fundamental insight. However, owing to the complexity of catalytic processes, the fleeting and frequently highly sensitive nature of intermediates and the associated challenges in gaining fundamental mechanistic understanding, insight-driven - developments and especially reactivity designs have so far been extremely rare. The objective of this proposal is to capitalize on the tools of experimental and computational chemistry as a powerful means to gain access to the fundamental mechanistic - details of key catalytic steps that are required to allow reactivity design. The specific subject for study will focus on the most significant challenges in nickel-catalysis - a highly promising area in the context of sustainability and synthetic - diversity owing to nickel’s relatively large abundance and also high reactivities towards relatively inert bonds. The proposed studies will address challenges in relation to Ni-catalyzed C-H activation, cross-coupling and trifluoromethylation - reactions, as well as the exploration of novel avenues in catalysis at multinuclear sites. - - 2020-04-30, ongoing project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - FunCatDesign - - - ERC-2014-STG - - - 637993 - - - - - RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN - RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN - - - EUR 1 786 563 - - - Engineering Quantum Error Correction - - - EUR 1 786 563 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This proposal will advance the theory of quantum error correction towards its application in real physical devices, in particular superconducting transmon qubit systems. The research will result in proposals for experiments: - how to use physical qubits to redundantly represent logical quantum information and how error information can be obtained and classically processed. The research will consider novel ways of using transmon qubits to achieve a universal fault-tolerant - surface code architecture. The research will produce a design of a universal fault-tolerant architecture in which qubits are encoded in the electromagnetic field of a (microwave) cavity. Research will also focus on mathematical and numerical studies - in quantum error correction which are technology-independent, but shed light on coding overhead, decoding efficiency and logical universality. - - 2021-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - EQEC - - - ERC-2015-CoG - - - 682726 - - - - - TECHNISCHE UNIVERSITEIT EINDHOVEN - KATHOLIEKE UNIVERSITEIT LEUVEN - RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN - INCAS 3 - RIJKSUNIVERSITEIT GRONINGEN - ANTEA NEDERLAND BV - - - EUR 3 632 486,25 - - - Exploring the Unknown through Reincarnation and Co-evolution - - - EUR 3 632 486,25 - - - Netherlands - Belgium - Germany - Netherlands - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Humans have been exploring the world from the depths of the oceans to the edges of the universe. Yet many environments remain inaccessible, even to modern cutting-edge technology. Therefore problems like exploring the status - of waste water under the Fukushima reactor, or discover suitable sites for underground CO2 storage remain unsolved. - - 2019-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-1-2014 - FET-Open research projects - - - RIA - Research and Innovation action - - - Netherlands - - - Phoenix - - - H2020-FETOPEN-2014-2015-RIA - - - 665347 - - - - - CRANFIELD UNIVERSITY - PANEPISTIMIO PATRON - PANEPISTIMIO IOANNINON - LULEA TEKNISKA UNIVERSITET - EXIS INNOVATION LTD - - - EUR 2 495 863 - - - An Advanced Methodology for the Inspection and Quantification of Damage on Aerospace Composites and Metals using an Innovative Approach - - - EUR 2 495 863 - - - United Kingdom - Greece - Greece - Sweden - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - There is an innovative need for more efficient and reliable damage inspection, reducing time and cost of aircraft infrastructures, as well as maintenance-especially C and D Checks- without compromising the safety of passengers - and goods transported. The CompInnova project is focused upon the development of an innovative inspection methodology, with automated and manual capabilities, for any type of composite and metallic aircraft structures. The novel structural integrity - approach is comprised by three parts: a qualified Phased Array (PA) and Infrared Thermography (IRT) method attached to a mobile Vortex robot, a Damage Tolerance (DT) structural integrity assessment technique processed on a computer and an innovative - repair system. - - 2019-02-28, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-1-2014 - FET-Open research projects - - - RIA - Research and Innovation action - - - United Kingdom - - - CompInnova - - - H2020-FETOPEN-2014-2015-RIA - - - 665238 - - - - - RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN - RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN - - - EUR 1 988 750 - - - Symbolic Analysis of Temporal and Functional Behavior of Networked Systems - - - EUR 1 988 750 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The goal of SYMBIOSYS is to assure the reliability and interoperability of networked (software) systems, a crucial requirement in today’s networked information society. To this end, we devise a software and systems analysis - methodology that – for the first time – considers the vital influence factors that determine the behavior of networked systems, especially including input and temporal uncertainty of network interactions. With SYMBIOSYS, we will be able to - automatically and effciently explore and analyze the vast amount of distributed execution paths in networked systems in a highly structured manner inspired by Symbolic Execution (SE). - - 2020-07-31, ongoing project - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - SYMBIOSYS - - - ERC-2014-CoG - - - 647295 - - - - - FORSCHUNGSZENTRUM JULICH GMBH - FORSCHUNGSZENTRUM JULICH GMBH - RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN - UNIVERSITA DEGLI STUDI DI FERRARA - - - EUR 2 379 276 - - - Search for electric dipole moments using storage rings - - - EUR 2 379 276 - - - Germany - Germany - Germany - Italy - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - One of the great mysteries in the natural sciences is the dominance of matter over antimatter in the universe. According to our present understanding, the early universe contained the same amount of matter and antimatter. If - the universe had behaved symmetrically as it developed, every particle would have been annihilated by one of its antiparticles. We therefore owe our very existence to mechanisms that have led to a world where something that we call matter remains. We - propose to study such mechanisms by searching for electric dipole moments (EDMs) of charged hadrons in a new class of precision storage rings. Our project will lay the foundations for a new European flagship research infrastructure. The breaking of - the combined charge conjugation and parity symmetries (CP-violation) in the Standard Model is not strong enough to explain the observed excess of matter and further sources of CP-violation must be sought. These sources could manifest themselves in - Electric Dipole Moments of elementary particles, which occur when the centroids of positive and negative charges are mutually and permanently displaced. The observation of an electric dipole moment will elucidate the mechanisms which led to the - matter that dominates the universe. Although the measurement principle, the time development of the polarization vector subject to a perpendicular electric field, is simple, the smallness of the effect makes this an enormously challenging project. - This can only be mastered through the common effort of an international team of accelerator and particle physicists, working closely with engineers. The proponents of this design study and the research environment at the Forschungszentrum Jülich - (Germany), including the conventional storage ring COSY, provide the optimal basis for one of the most spectacular possibilities in modern science: finding an EDM as a signal for new physics beyond the Standard Model and perhaps explaining the puzzle - of our existence. - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - srEDM - - - ERC-2015-AdG - - - 694340 - - - - - RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN - RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN - - - EUR 2 500 000 - - - A Sequence Classification Framework for Human Language Technology - - - EUR 2 500 000 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project will develop a unifying framework of novel methods for sequence classification and thus make a major break-through in automatic speech recognition and machine translation, advancing these areas of human language - technology (HLT) beyond state-of-the-art. Despite the huge progress made in the field, the specific aspect of sequence classification has not been addressed adequately in the past research in these disciplines and remains a big challenge. The - proposed project will provide a novel framework under consistent consideration of the leading aspect of sequence classification. It will break the ground for a deeper, more comprehensive foundation for sequence classification and pave the way for a - new generation of algorithms that will put human language technology on a more solid basis and that will accelerate progress in the field across several disciplines. - - - 2021-07-31, ongoing project - - - 2016-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - SEQCLAS - - - ERC-2015-AdG - - - 694537 - - - - - UNIVERSIDAD DE SEVILLA - - - EUR 158 121,60 - - - Mastering the energetic particle distribution in a magnetohydrodynamic active plasma - - - EUR 158 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - FIREFELM – fast ions, radial electric field and edge localized mode – is an interdisciplinary project aimed at getting a better understanding of the basic mechanisms responsible for the energetic particle transport in fusion - as well as in astrophysical plasmas making use of advanced diagnostic systems and state-of-the-art numerical tools. The main goal of this proposal is to control the dynamics between energetic particles, radial electric fields and magnetohydrodynamic - (MHD) perturbations in the plasma edge and its impact on the overall plasma confinement. The mechanisms underlying the fast ion transport induced by MHD instabilities, such as Edge Localized Modes (ELMs) and externally applied Magnetic Perturbations - (MPs) will be studied through innovative diagnosis techniques developed at the University of Seville and the Centro Nacional de Aceleradores (CNA) in Seville, Spain and employed in different fusion devices such as ASDEX Upgrade (Germany) and MAST - Upgrade (UK). This project consists of three main research lines which follow a bottom up approach: the first research line is dedicated to fusion technology and aims at the development of the new generation of fast ion loss detectors (FILDs). New - FILD systems will be able to provide absolute fluxes of escaping ions, their poloidal distribution and critical information on the wave-particle momentum and energy exchange. These advanced FILDs will be employed to characterize the interdependence - between fast ion losses and radial electric fields and to study the role of fast ions in plasma edge stability and in the ELM cycle. Unraveling the interaction between MHD instabilities and energetic particles in tokamak plasmas will advance our - understanding of the observed particle acceleration and transport in the solar corona and help to identify similarities between tokamak and astrophysical plasmas. This third research line will shed light on the anomalous heating of the solar corona - and generation of the solar wind. - - 2019-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - FIREFELM - - - H2020-MSCA-IF-2015 - - - 708257 - - - - - PANEPISTIMIO IOANNINON - - - EUR 168 391,80 - - - Identity matching from still images without face information - - - EUR 168 391,80 - - - Greece - - - Higher or Secondary Education Establishments - - In computer vision, human identity matching from images and/or video has been an active research topic for more than two decades and its popularity is increasing with the increase in computing power. The state of the art - techniques are based on face images and gait recognition from long video sequences. However, in many real applications only some static images of the subject may be available where face information is missing (e.g. posterior views). These scenarios - have not been addressed by the research community as they are difficult to handle. In this action, we propose a method for matching identities from a set of 2D images of a person without any facial information. The method consists of two steps: at - first, the human body is modelled by a 3D articulated model whose pose is estimated by its 2D projections onto the images. Then, biometric features are computed by fitting 3D deformable models to the image data, thus capturing the form and size of - the main parts of the anatomy. The overall framework works under a probabilistic framework, with a learning step, in order to encode pose and anatomy variations between a set of individuals that are to be identified. - - 2017-08-31, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Greece - - - StillNoFace - - - H2020-MSCA-IF-2014 - - - 656094 - - - - - PANEPISTIMIO IOANNINON - - - EUR 164 653,20 - - - Location Based Suggestion of Keyword Queries - - - EUR 164 653,20 - - - Greece - - - Higher or Secondary Education Establishments - - Query suggestion is a recent and important add-on feature of Web search engines (e.g., Google), which helps users to express their information needs precisely. Specifically, given the fact that the user may not be able to find - appropriate keywords for her search, the system recommends to her a small set of keyword queries that are likely to match her original intention. As an example, when a user searches for “convertible car,” she may miss all the documents indexed under - “cabriolet.” Therefore, the engine suggests “cabriolet” as a follow-up query to the user. There has been extensive research in the past decade on effective query suggestion. However, none of the existing keyword query suggestion methods consider the - user’s location. We argue that the queries suggested to a user not only should be semantically relevant to her original query, but also should give results near the user’s location, especially when these queries are expressed by a mobile user; - otherwise, the suggested queries might not be of interest to the user. Therefore, there is a need for effective location-based keyword query suggestion (LBKQS) models. The objectives of this project are (1) the development of LBKQS models, (2) the - evaluation of the proposed models, (3) the development of efficient and scalable LBKQS techniques based on the most effective models. In the end, we expect our system to provide appropriate query suggestions to mobile users in real-time. - - 2017-03-31, closed project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Greece - - - LBSKQ - - - H2020-MSCA-IF-2014 - - - 657347 - - - - - UMEA UNIVERSITET - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - OREBRO UNIVERSITY - BEN-GURION UNIVERSITY OF THE NEGEV - UNIVERSITY OF THE WEST OF ENGLAND, BRISTOL - UNIVERSITAET HAMBURG - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - - - EUR 3 874 726,44 - - - SOcial Cognitive Robotics in The European Society - - - EUR 3 874 726,44 - - - Sweden - Spain - Sweden - Israel - United Kingdom - Germany - Germany - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - SOCRATES is a PhD training program for 15 young researchers, created to develop the field of Social Robotics with an application focus on Robotics in Eldercare. - - - 2020-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Sweden - - - SOCRATES - - - H2020-MSCA-ITN-2016 - - - 721619 - - - - - UNIVERSITAET BREMEN - UNIVERSITAET BREMEN - - - EUR 150 000 - - - Surface modulation of wounds: heal by inhalants!Novel drug-based treatment for excessive scars and chronic wounds. - - - EUR 150 000 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The innovative concept of the ERC Starting Grant project “Keratinocytes and Matrix metalloproteinases: driving force of skin wound contraction?” was to use inhalants for skin wounds and it proved to be excellent and - functional. Surface Modulation of Wounds (SUMOWO) with these anti-inflammatory, pro-migratory and anti-fibrotic compounds will be beneficial for chronic wound healing and reduce excessive scarring. This novel drug-based treatment strategy marks a - novel era of wound care. A clinical phase 1 study on healthy volunteers is planned to show the product’s safety and tolerability for skin use – the first step towards clinical application. The goal of SUMOWO is to deliver clinical proof of concept, - to provide a thorough market analysis with contact to key-players, to secure our intellectual property rights on an international platform, to accelerate commercial exploitation and ultimately, to restore patients’ life quality. - - 2017-12-31, closed project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2015 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Germany - - - SUMOWO - - - ERC-2015-PoC - - - 693017 - - - - - KATHOLIEKE UNIVERSITEIT LEUVEN - HELSINGIN YLIOPISTO - RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN - KUNGLIGA TEKNISKA HOEGSKOLAN - NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA - TARTU ULIKOOL - MEAB CHEMIE TECHNIK GMBH - MYTILINEOS ANONIMI ETAIRIA - OMILOS EPICHEIRISEON - ALOUMINION TIS ELLADOS VIOMICHANIKI KAI EMPORIKI ANONYMOS ETAIREIA VEAE - TITAN CEMENT COMPANY AE - - - EUR 3 720 893,40 - - - European Training Network for Zero-waste Valorisation of Bauxite Residue (Red Mud) - - - EUR 3 720 893,40 - - - Belgium - Finland - Germany - Sweden - Greece - Estonia - Germany - Greece - Greece - Greece - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - To tackle its (critical) raw material dependency, Europe needs comprehensive strategies based on sustainable primary mining, substitution and recycling. Freshly produced flows and stocks of landfilled industrial residues such - as mine tailings, non-ferrous slag and bauxite residue (BR) can provide major amounts of critical metals and, concurrently, minerals for low-carbon building materials. The European Training Network for Zero-Waste Valorisation of Bauxite Residue - (REDMUD) therefore targets the vast streams of new and stockpiled BR in the EU-28. BR contains several critical metals, is associated with a substantial management cost, whereas spills have led to major environmental incidents, including the Ajka - disaster in Hungary. To date, zero-waste valorisation of BR is not occurring yet. The creation of a zero-waste BR valorisation industry in Europe urgently requires skilled scientists and engineers, who can tackle the barriers to develop fully - closed-loop environmentally-friendly recovery flow sheets. REDMUD trains 15 researchers in the S/T of bauxite residue valorisation, with emphasis on the recovery of Fe, Al, Ti and rare earths (incl. Sc) while valorising the residuals into building - materials. An intersectoral and interdisciplinary collaboration of EU-leading institutes and scientists has been established, which covers the full value chain, from BR to recovered metals and new building materials. Research challenges include the - development of efficient extraction of Fe, Al, Ti and rare earths (incl. Sc) from distinct (NORM classified) BRs and the preparation of new building materials with higher than usual Fe content. By training the researchers in pyro-, hydro- and - ionometallurgy, electrolysis, rare-earth extraction and separation technology, inorganic polymer and cement chemistry, Life Cycle Assessment (LCA), NORM aspects and characterisation, they become the much needed scientists and engineers for the - growing European critical raw materials industry. - - 2018-11-30, ongoing project - - - 2014-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Belgium - - - REDMUD - - - H2020-MSCA-ITN-2014 - - - 636876 - - - - - UNIVERSITA DEGLI STUDI DI TORINO - POLITECNICO DI TORINO - UNIVERSITAT POLITECNICA DE VALENCIA - AALBORG UNIVERSITET - PANEPISTIMIO IOANNINON - ACEA PINEROLESE INDUSTRIALE SPA - LIQTECH AS - - - EUR 630 000 - - - Enhancing water quality by developing novel materials for organic pollutant removal in tertiary water treatments - - - EUR 630 000 - - - Italy - Italy - Spain - Denmark - Greece - Italy - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The MAT4TREAT project consists in a consortium of 8 Universities, 5 of them European (UNITO, AAU, POLITO, UPV and UOI), and the other three from outside the EU (UNLP, McGill, SU), as well as two non academic institutions (ACEA - and LQT). These groups are committed to work in the development of novel materials to be used in innovative integrated water tertiary treatments (to remove, for instance, Emerging Pollutants). This ambitious goal will be achieved by world leading - research groups in the following fields: (i) graphene-based and other carbon-related materials, (ii) polymeric materials, (iii) oxidic ceramic materials, and (iv) hybrid inorganic-polymeric materials. - - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Italy - - - MAT4TREAT - - - H2020-MSCA-RISE-2014 - - - 645551 - - - - - UNIVERSITY OF BATH - UNIVERSITY OF BATH - - - EUR 789 823,77 - - - Externally Tuneable Separations for Membrane Reactors - - - EUR 789 823,77 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - I will develop an all new type of reactor for pharmaceutical and chemical process applications – the ‘tuneable membrane reactor’. These contain ground-breaking conducting polymer composite membranes that will allow in-situ - tuning of the molecular selectivity for both neutral and charged species through them. This is revolutionary: current state-of-the-art membranes can be electrically tuned for charged species only. The project is timely, developing a new technology - that can give the EU a competitive advantage for our declining pharmaceutical and (petro)chemical manufacturing base and builds on my recent research innovations. - - 2018-02-28, ongoing project - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - TUNEMEM - - - ERC-2014-CoG - - - 646769 - - - - - DANMARKS TEKNISKE UNIVERSITET - BAYER TECHNOLOGY SERVICES GMBH - Bayer AG - UNIVERSITE LYON 1 CLAUDE BERNARD - UNIVERSITY OF STRATHCLYDE - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - ALFA LAVAL COPENHAGEN A/S - UNILEVER U.K. CENTRAL RESOURCES LIMITED - RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN - - - EUR 4 090 249,44 - - - Advancing Modelling for Process-Product Innovation, Optimization, Monitoring and Control in Life Science Industries - - - EUR 4 090 249,44 - - - Denmark - Germany - Germany - France - United Kingdom - United Kingdom - Denmark - United Kingdom - Germany - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - The ModLife project is a European Training Network initiative that brings together 5 leading European universities, 4 global industrial players and 2 SMEs to undertake research and training in the area of product-process - innovation, optimization monitoring and control for life sciences and biotechnology industries. Modlife aims to develop Advanced Model-Based Optimization, Monitoring and Control as Enabling Technologies for bioprocess-product development and - innovation tailored for the needs in life science industries. ModLife ETN will address excellence in research and training of next generation biochemical and process engineers in life sciences industries through: (1) Offering comprehensive training - and knowledge transfer opportunities in multidisciplinary and multi-sectoral fields for training early stage researchers with multidisciplinary knowledge and competences bridging engineering and life sciences (2) Integrating and creating synergies - among individually excellent but otherwise fragmented bioprocess engineering research centers across the European union in life sciences and biotechnology industries, (3) Building on advances in modeling and simulation, to develop cutting edge - model-based enabling technologies and applications for optimization, monitoring and control for bioprocess and product development and innovation. - - 2019-10-31, ongoing project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Denmark - - - ModLife - - - H2020-MSCA-ITN-2015 - - - 675251 - - - - - THE CYPRUS INSTITUTE - BERGISCHE UNIVERSITAET WUPPERTAL - RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN - TECHNISCHE UNIVERSITEIT EINDHOVEN - UNIVERSITY OF CYPRUS - UNIVERSITA DEGLI STUDI DI FERRARA - UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA - - - EUR 3 723 916,32 - - - High Performance Computing in Life Sciences, Engineering And Physics - - - EUR 3 723 916,32 - - - Cyprus - Germany - Germany - Netherlands - Cyprus - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Progress in computers and algorithms in the last years has made numerical simulation and modelling a key research methodology in both academia and industry, which in turn drives exascale computing in order to maintain - excellence in research and innovation. A disruptive evolution in computer technologies is required for attaining exascale performances in the coming years bringing challenges that urgently need to be addressed across science and engineering fields. - Therefore new interdisciplinary strategies are required in order to educate the next generation of scientists to address such challenges enabling them to be at the forefront of their respective research fields. Instead of the traditional - domain-specific training, integrated approaches are needed that can be best implemented by collaborative networks of universities, research institutes and industrial partners. We propose a highly interdisciplinary joint doctorate program realized by - bringing together world-leading experts in applied mathematics, high performance computing technologies, particle and nuclear physics, fluid dynamics and life sciences to appropriately train researchers in Europe to exploit high performance - computing, advance science and promote innovation. Students will be trained in mathematical and computational concepts underpinning current and future numerical simulations in turbulent flows, computational biology and lattice quantum chromodynamics. - The research projects are designed to enhance collaborations and interactions across these disciplines, integrating non-academic partners, and to develop methodologies that efficiently use large-scale numerical simulations on future high performance - computer systems. Students who complete this training program will be versatile to undertake highly interdisciplinary projects, well positioned to embark on a successful career in academia or the industrial sector. - - 2019-03-31, ongoing project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-EJD - Marie Skłodowska-Curie Innovative Training Networks (ITN-EJD) - - - MSCA-ITN-EJD - European Joint Doctorates - - - Cyprus - - - HPC-LEAP - - - H2020-MSCA-ITN-2014 - - - 642069 - - - - - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN - EML EUROPEAN MEDIA LABORATORY GMBH - CEDAT 85 SRL - - - EUR 414 000 - - - Hands-free Voice-enabled Interface to Web Applications for Smart Home Environments - - - EUR 414 000 - - - Greece - Germany - Germany - Italy - - - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Nowadays, it is becoming increasingly affordable to enhance the home environment with several automation schemes, allowing remote control of e.g., heating/cooling, communication, lighting, media, etc. Such smart home - functionalities are essential for people with disabilities and the elderly, as they not only provide assistive control of important everyday functionalities, but may prove to be life-saving in case of emergency. However, smart home functionalities - may become useless for people who need those most, if they cannot be accessed via a natural, easy to use, interface. - - 2019-05-31, ongoing project | - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Greece - - - LISTEN - - - H2020-MSCA-RISE-2014 - - - 644283 - - - - - THE UNIVERSITY OF BIRMINGHAM - AnalytiCon Discovery GmbH - MERCACHEM BV - - - EUR 1 565 180,58 - - - Delivering Better Starting Points for Drug Discovery: New Compound Libraries Driven By Intelligent Design - - - EUR 1 565 180,58 - - - United Kingdom - Germany - Netherlands - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Whilst the need to generate new therapeutics has never been more important, drug discovery is at the same time becoming much more difficult. In short, we need to be more efficient at developing drugs. One way of achieving this - is to reduce the attrition rates, which currently blight the drug-discovery process, by populating compound screening libraries with more structurally diverse and higher quality, i.e. designed, molecules to provide better starting points for drug - development. Pharma also needs a new type of researcher given an increasing proportion of scientists are now finding employment in smaller companies, where they need to be more flexible, entrepreneurial and business-aware. iDESIGN seeks to address - these key challenges by combining the complementary expertise from both academic and industrial sectors. iDESIGN has the following Principal Objectives: 1) to use the ESRs' individual research projects to develop new, structurally diverse, 'smart' - compound libraries for the sector to use in hit-identification screening campaigns; 2) to provide a training programme which will see the ESRs becoming expert synthetic and medicinal chemists, confident research scientists, consummate professionals, - effective communicators and innovators with a creative and entrepreneurial spirit. iDESIGN will begin with an academic training phase, during which the ESRs will undertake project-wide training whilst acquiring the synthesis skills to generate - bespoke molecular scaffolds, which they will elaborate and validate using in silico and experimental methods. The ESRs will then transfer to one of the industrial partners to take full advantage of their Industrial Supervisors' expertise and the - available instrumentation to complete the library-generation aspect of their research projects. All 6 ESRs will return to Birmingham for their final 2 months to allow their Academic Supervisors to oversee directly the final stages of their PhD thesis - preparation. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-EID - European Industrial Doctorates - - - United Kingdom - - - iDESIGN - - - H2020-MSCA-ITN-2017 - - - 765116 - - - - - RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN - - - EUR 257 860,80 - - - Operator algebraic approach to topological phases - - - EUR 257 860,80 - - - Germany - - - Higher or Secondary Education Establishments - - Topologically ordered phases are a new state of matter, discovered only around the late '80s. In recent years interest in such states has sparked, one of the reasons being applications to topological quantum computing: the - topological properties make the state robust against perturbations, making them ideal components in an environment where (thermal or other) noise is one's biggest enemy. By now there is a plethora of examples of topologically ordered states, whose - only unifying feature seems to be that they do not fall into the Landau theory of phases. Although there are many examples, the mathematical framework to rigorously study such systems is less clear, in particular if one wants to consider both - so-called long range entangled phases and symmetry protected phases. The goal of this project is to tackle this problem. - - 2018-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Germany - - - OATP - - - H2020-MSCA-IF-2014 - - - 657004 - - - - - UNIVERSITA DEGLI STUDI DI VERONA - - - EUR 1 098 720 - - - INnovative Verona university’s Inter-disciplinary, Inter-sectoral and International Training Experience - - - EUR 2 197 440 - - - Italy - - - Higher or Secondary Education Establishments - - INVITE is a doctoral programme at the University of Verona (UNIVR), Italy, with a strong inter-sectoral, inter-disciplinary and international research and training dimension. The project is co-financed by the Regione del - Veneto and involves many partner organisations: 17 universities and research centres in Europe and beyond, 13 enterprises and organisations from the economic sector, 3 public organisations and 1 network. - - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2016 - Co-funding of regional, national and international programmes - - - MSCA-COFUND-DP - Doctoral programmes - - - Italy - - - INVITE - - - H2020-MSCA-COFUND-2016 - - - 754345 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 263 440,80 - - - Understanding how plants overcome drought by controlling stomatal function: applicability and impacts on agriculture - - - EUR 263 440,80 - - - Spain - - - Research Organisations - - Land plants have coped with drought since they first colonized dry land. Drought is the most frequent cause of water stress – a functional and structural plant response to low water availability. An understanding of the - impact, mechanisms and traits underlying drought tolerance in agricultural plant species is essential to improve productivity, and it further represents a major European priority (SFS-01-2016): optimizing agriculture in a changing climate with - reduced water availability and a growing population. To address this urgent need it is necessary to first understand how stomata regulate leaf gas exchange, since stomatal is the main limitation of photosynthesis in crops under water stress. Both - hydraulic and non-hydraulic or hormonal signals are the main drivers of stomatal regulation. Therefore, AgroPHYS proposes to investigate how these signals interact to protect plants against damaging desiccation. This project will generate - physiological knowledge, at UTAS, from a range of experimental techniques and apply it to a physiology-based model and an automatic plant-based sensor to guide both irrigation management and research, at IRNAS-CSIC. The objectives of AgroPHYS are (i) - to evaluate the relative importance and coordination of hydraulic and hormonal signals in plant stomatal responses to drought and recovery, and (ii) to apply this knowledge, by means of a mechanistic model and a plant sensor, to predict productivity - relative to water consumption in agricultural plant species with different water use strategies. The outgoing research group is at the cutting-edge of physiological research and the environment of learning will provide maximum benefit to the - candidate and excellent opportunities to interact with researchers from across the globe. These skills and knowledge will be transferred back to IRNAS-CSIC, providing essential data not only for scientific research on plant function but also for - precision agriculture and optimal management of irrigation. - - 2020-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Spain - - - AgroPHYS - - - H2020-MSCA-IF-2016 - - - 751918 - - - - - FUNDACIO PRIVADA INSTITUT CATALA D'INVESTIGACIO QUIMICA - FUNDACIO PRIVADA INSTITUT CATALA D'INVESTIGACIO QUIMICA - - - EUR 150 000 - - - Separation membranes for carbon dioxide removal from gas streams - - - EUR 150 000 - - - Spain - Spain - - - Research Organisations - Research Organisations - - Carbon dioxide separation, capture and utilization is expected to become a major business opportunity in the near future. Beyond current industrial needs for natural gas or biogas purification, regulatory issues imposing - emission control will also contribute to a fast growth in this market. At the industrial level, CO2 separation is still an expensive process, typically based in alkaline amine solutions or cryogenic distillation, and low-cost alternatives are needed. - Membrane-based technologies are the most preferred for gas purification processes due to their easy implementation and very low operational costs. However, CO2 separation through membrane systems is not competitive nowadays, due to the low - selectivity and poor stability of the available materials. This weakness precludes fully exploitation of the intrinsic benefits (functional and economic) of membrane technologies. - - 2019-10-31, Grant Agreement signed - - - 2018-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Spain - - - MEMCARB - - - ERC-2017-PoC - - - 780255 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 183 454,80 - - - Dissection of the mammalian transcription termination mechanism by CRISPRi technology. - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - RNA polymerase II (RNAPII) transcribes protein-coding genes in eukaryotes. The proper RNAPII transcription termination is crucial for generation of functional mRNAs, and then proteins. Termination, or stop of RNA synthesis, - may occur before or after mRNA 3’-end cleavage and polyadenylation. In the last decade many details have been acquired about mRNA maturation, but still little is known about the termination per se. In this proposal I will redress this problem. - - 2019-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - dCas9 - - - H2020-MSCA-IF-2016 - - - 747391 - - - - - UNIVERSITEIT UTRECHT - - - EUR 165 598,80 - - - Towards a mathematical conjecture for the Landau-Ginzburg/conformal field theory correspondence and beyond - - - EUR 165 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Initially a model to describe superconductivity, Landau-Ginzburg (LG) models were promoted in the late 80s to supersymmetric quantum field theories (QFTs) completely characterized by a polynomial W called potential. They - gained importance in string theory and algebraic geometry as they play an interesting role in homological mirror symmetry. On the other hand, conformal field theories (CFTs) have been another kind of QFTs which display conformal symmetry. They have - focused many efforts to understand the mathematical structures which encode them, e.g. inspiring the definition of vertex operator algebras (Borcherds, Fields medalist ’88) or pushing forward our knowledge of modular tensor categories. Despite - seeming two very different topics, LG models and CFTs are intimately related via a result of theoretical physics — the LG/CFT correspondence— stating that the infrared fixed point of a LG model with potential W is a CFT of central charge c(W). - Mathematically this implies equivalences of categories of matrix factorizations (which describe defects of LG models) and categories of representations of vertex operator algebras (which describe defects of CFT). Up to date, we lack a complete - understanding of the LG/CFT correspondence and we only have a few examples. The main goal of this Marie Curie is to find a mathematical statement for it, via completing a list of examples, exploring their properties (e.g. tensoriality or even - modularity of the categories) and then attacking the main goal. Utrecht University (host institution) is one of the few places in Europe hosting experts in representation, category and Galois theory and mathematical physics, providing exactly the - necessary and complementary expertise required to achieve this goal. These results will build a surprising bridge between very different areas of mathematics, opening new research gates completely inspired by physics. - - 2019-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - MACOLAB - - - H2020-MSCA-IF-2016 - - - 747555 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - UNIVERSITE CLERMONT AUVERGNE - COMMUNAUTE D' UNIVERSITES ET ETABLISSEMENTS UNIVERSITE BOURGOGNE - FRANCHE - COMTE - UNIVERSITA DEGLI STUDI DI UDINE - UNIVERSIDADE DE COIMBRA - UNIVERSITEIT GENT - IMASENIC ADVANCED IMAGING S.L. - - - EUR 2 266 907,76 - - - AdvanCed Hardware/Software Components for Integrated/Embedded Vision SystEms - - - EUR 2 266 907,76 - - - Spain - France - France - Italy - Portugal - Belgium - Spain - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - ACHIEVE-ETN aims at training a new generation of scientists through a research programme on highly integrated hardware-software components for the implementation of ultra-efficient embedded vision systems as the basis for - innovative distributed vision applications. They will develop core skills in multiple disciplines, from image sensor design to distributed vision algorithms, and at the same time they will share the multidisciplinary background that is necessary to - understand complex problems in information-intensive vision-enabled applications. Concurrently, they will develop a set of transferable skills to promote their ability to cast their research results into new products and services, as well as to boost - their career perspectives overall. Altogether, ACHIEVE-ETN will prepare highly skilled early-stage researchers able to create innovative solutions for emerging technology markets in Europe and worldwide but also to drive new businesses through - engaging in related entrepreneurial activities. The consortium is composed of 6 academic and 1 industrial beneficiaries and 4 industrial partners. The training of the 9 ESR’s will be achieved by the proper combination of excellent research, - secondments with industry, specific courses on core and transferable skills, and academic-industrial workshops and networking events, all in compliance with the call’s objectives of international, intersectoral and interdisciplinary mobility. - - 2021-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Spain - - - ACHIEVE - - - H2020-MSCA-ITN-2017 - - - 765866 - - - - - RIJKSUNIVERSITEIT GRONINGEN - UNIVERSITA DEGLI STUDI DI PAVIA - SANKO TEKSTIL ISLETMELERI SANAYI VETICARET ANONIM SIRKETI - RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN - TECHNISCHE UNIVERSITAET GRAZ - SESAM-BIOTECH GMBH - NORGES MILJO-OG BIOVITENSKAPLIGE UNIVERSITET - UNIVERSITY OF YORK - DSM FOOD SPECIALTIES BV - WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER - - - EUR 3 078 262,44 - - - Harnessing the power of enzymatic oxygen activation - - - EUR 3 078 262,44 - - - Netherlands - Italy - Turkey - Germany - Austria - Germany - Norway - United Kingdom - Netherlands - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - For the selective and effective incorporation of oxygen into biological molecules (oxygenation reaction), several enzyme types have evolved in nature. They catalyse crucial reactions in various metabolic routes. The chemistry - feasible with these biocatalysts is unrivalled when compared with conventional chemical methods. Therefore, these oxygenating enzymes are very promising tools in biotechnological approaches. However, when compared with other enzyme classes, such as - hydrolases, oxygenases are still in their infancy considering their biotechnological potential. To fully exploit the catalytic power of oxygenases, several hurdles have to be taken for which a higher level of knowledge on these enzymes is needed - while also technical aspects have to be solved. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Netherlands - - - OXYTRAIN - - - H2020-MSCA-ITN-2016 - - - 722390 - - - - - KUNGLIGA TEKNISKA HOEGSKOLAN - KUNGLIGA TEKNISKA HOEGSKOLAN - - - EUR 150 000 - - - Dried Blood Spot sampling at home in Therapeutic Drug Monitoring - - - EUR 150 000 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - A new disposable sampling device that allows quantitative measurements from Dried Blood Spots (DBS) has been developed with support of the ERC AdG xMEMS. - - 2018-03-31, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Sweden - - - xMEMSDBS - - - ERC-2016-PoC - - - 727818 - - - - - IBM RESEARCH GMBH - - - EUR 175 419,60 - - - Monolithic Optoelectronic Devices on Silicon - - - EUR 175 419,60 - - - Switzerland - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Nowadays, microelectronics set the pace for the whole knowledge-based economy and society in terms of the ever rising demand for mobile devices and the exponentially growing internet data transfer. However, the widening gap - between the increasing number of transistors on a single Si chip and the delivered performance indicates the approaching limits of classical device scaling. Additionally, this miniaturization results in severe energy dissipation in the - interconnection of devices. A smart way to overcome this emerging power consumption crisis is to avoid heating by replacing the on-chip and/or chip-to-chip electrical interconnects with optical interconnects. Due to their direct bandgap, III-V - compounds are ideal for the integration of photonics with Si-based electronics on the very same chip. This would enable large-scale optoelectronics integration hindered so far by coupling- and overlay issues introduced by state-of-the-art III-V - bonding on Silicon. - - - 2018-06-30, Grant Agreement terminated - - - 2016-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - MODES - - - H2020-MSCA-IF-2015 - - - 704045 - - - - - DANMARKS TEKNISKE UNIVERSITET - TECHNISCHE UNIVERSITEIT DELFT - RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN - SILICOLIFE LDA - CHALMERS TEKNISKA HOEGSKOLA AB - SESAM-BIOTECH GMBH - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - - - EUR 3 994 075,80 - - - Predictive and Accelerated Metabolic Engineering Network - - - EUR 3 994 075,80 - - - Denmark - Netherlands - Germany - Portugal - Sweden - Germany - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - The world economy is dependent on fossil resources: oil, gas and coal. The fossil resources are finite and their consumption causes catastrophic environmental changes. Therefore we need to move towards sustainable economy - using renewable resources for energy and chemicals production. Via metabolic engineering approach, novel microbial cells can be created that can convert biomass and waste into fuels and chemicals. Metabolic engineering however distinguishes itself - from other engineering disciplines by low predictability of the design and long turnover times for the cell factory construction and screening. Therefore there is a need for scientists, who can address these challenges. - - 2020-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Denmark - - - PAcMEN - - - H2020-MSCA-ITN-2016 - - - 722287 - - - - - UNIVERSITY OF SOUTHAMPTON - INSTITUT DE RECHERCHES EN INGENIERIE DES SURFACES SAS - UNIVERSIDAD DE BURGOS - INSTITUTO PEDRO NUNES ASSOCIACAO PARA A INOVACAO E DESENVOLVIMENTO EM CIENCIA E TECNOLOGIA - JIHLAVAN, AS - CESKE VYSOKE UCENI TECHNICKE V PRAZE - JOHN CRANE UK LIMITED - ARTIA NANO - ENGINEERING & CONSULTING IKE - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - - - EUR 3 510 527,04 - - - SOLUTION - Solid lubrication for emerging engineering applications - - - EUR 3 510 527,04 - - - United Kingdom - France - Spain - Portugal - Czech Republic - Czech Republic - United Kingdom - Greece - Greece - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Jiri Matas - Tel.: +420 22435721 - Fax: +420 224357385 - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - - SOLUTION will provide research and training program for 14 early stage researchers (ESR) pursuing their PhD in various disciplines covering the broadly defined area of solid lubricant coatings. The project combines theoretical - approaches represented by advanced nanoscale simulations, laboratory design and fabrication of novel solid lubricants supported by simulations, and the up-scaling of promising solutions and their application in selected emerging engineering - applications. - - 2021-01-31, ongoing project - - - 2017-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - SOLUTION - - - H2020-MSCA-ITN-2016 - - - 721642 - - - - - UNIVERSITE DE RENNES I - ELASTISYS AB - TECHNISCHE UNIVERSITAET BERLIN - U-HOPPER SRL - - - EUR 2 067 625,44 - - - FogGuru: Training the Next Generation of European Fog Computing Experts - - - EUR 2 067 625,44 - - - France - Sweden - Germany - Italy - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - "A survey of 1000+ IT professionals has shown that the biggest challenge faced by the cloud computing industry today is the ""lack of [human] resources / expertise"". The objective of FogGuru is to train eight talented - early-stage researchers with an innovative and intersectoral research program to constitute the next generation of European Cloud and Fog computing experts. Besides their scientific and technical education, FogGuru ESRs will receive extensive - training in technological innovation and entrepreneurship as well as soft skills. These combined skills will enable them to fully master the innovation process stemming from fundamental research towards invention and development of innovative - products and services, and to real-life deployment, experimentation and engagement with beta-testers. - - 2021-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-EID - European Industrial Doctorates - - - France - - - FogGuru - - - H2020-MSCA-ITN-2017 - - - 765452 - - - - - BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION - UNIVERSITAET STUTTGART - FORSCHUNGSZENTRUM JULICH GMBH - NUMERICAL ALGORITHMS GROUP LTD - RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN - TERATEC - - - EUR 4 048 845 - - - Performance Optimisation and Productivity - - - EUR 4 048 845 - - - Spain - Germany - Germany - United Kingdom - Germany - France - - - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Other - Higher or Secondary Education Establishments - Other - - High performance Computing is becoming a fundamental tool for the progress of science and engineering and as such for economic competitiveness. The growing complexity of parallel computers is leading to a situation where code - owners and users are not aware of the detailed issues affecting the performance of their applications. The result is often an inefficient use of the infrastructures. Even when the need to get further performance and efficiency is perceived, code - developers may not have sufficient insight on its detailed causes for addressing the problem properly. This may lead to blind attempts to restructure codes and consequent lack of efficiency. - - - 2018-03-31, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.3."> - - - EINFRA-5-2015 - Centres of Excellence for computing applications - - - RIA - Research and Innovation action - - - Spain - - - POP - - - H2020-EINFRA-2015-1 - - - 676553 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 185 076 - - - Conserving the Legacy of Evolution into the Future - - - EUR 185 076 - - - France - - - Research Organisations - - Conserving the Legacy of Evolution (CLEF) would provide a comprehensive framework for translating biodiversity datasets into conservation plans. We now have a unique opportunity to improve the outlook for biodiversity by - taking advantage of the wealth of newly available data on species ranges, functional characteristics, and phylogenetic data. CLEF proposes to: (1) develop sophisticated, yet easy-to-use biodiversity models that improve our understanding of where - diversity occurs and better predict how diversity might change in the future, and (2) integrate the output of these biodiversity models with systematic conservation planning. CLEF would advance a new generation of biodiversity modelling that - considers multiple species in one step rather than the standard practice of estimating species diversity by aggregating individual models. Early work has suggested these multi-species biodiversity models show great promise for improving present and - future biodiversity estimates, but these models have yet to be comprehensively tested. Here, we will build and test these models for plant species in the French Alps, and compare the outputs to existing process-based models at identical scale and - resolution. The second phase of CLEF is to develop a tool that directly uses the outputs of these models in conservation prioritization software. This tool will have the option of including phylogenetic, functional data, and future distributions by - building on recent developments in this area. CLEF will demonstrate this approach for 2700 plant species to assign conservation priorities for the entire French Alps Region considering functional diversity, evolutionary diversity, climate and - land-use change and protected area status. The methods resulting from CLEF could be used for any species-level biodiversity dataset—helping scientists and conservationists better understand, predict, and plan to keep evolution’s legacy intact. - - 2017-08-31, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - CLEF - - - H2020-MSCA-IF-2014 - - - 659422 - - - - - THE UNIVERSITY OF BIRMINGHAM - UNIVERSITA CA' FOSCARI VENEZIA - ASTON UNIVERSITY - FONDAZIONE PER LA RICERCA E L'INNOVAZIONE - UNIVERSIDAD DE GRANADA - LUNDS UNIVERSITET - UNIVERSITE DE MONTPELLIER - HOCHSCHULE KARLSRUHE-TECHNIK UND WIRTSCHAFT - UNIONE REGIONALE DELLE CAMERE DI COMMERCIO INDUSTRIA, ARTIGIANATO E AGRICOLTURA DEL VENETO - CENTRE FOR EUROPEAN POLICY STUDIES - STEINBEIS TRANSFERZENTREN GMBH AN DER HOCHSCHULE KARLSRUHE - VERKET FÖR INNOVATIONSSYSTEM - GALDON SOFTWARE SA - RIEKE PACKAGING SYSTEMS LIMITED - BUREAU SATORI SAS - UNIVERSITE DE NEUCHATEL - NATIONAL UNIVERSITY OF SINGAPORE PUBLIC COMPANY LIMITED BY GUARANTEE - CORNELL UNIVERSITY - THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - UNIVERSITY OF SAN DIEGO - - - EUR 1 057 500 - - - Smart Manufacturing for EU Growth and Prosperity - - - EUR 1 057 500 - - - United Kingdom - Italy - United Kingdom - Italy - Spain - Sweden - France - Germany - Italy - Belgium - Germany - Sweden - Spain - United Kingdom - France - Switzerland - Singapore - United States - United States - United States - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - MAKERS will bring together leaders from business, academia and policy to study issues related to the drivers and dynamics of sustaining the competitiveness of EU manufacturing sectors. The project’s innovative research, - training and mobility activities will address key concerns related to the historic opportunity for the EU to lead a manufacturing renaissance that not only upgrades existing manufacturing competences but, more importantly, develops new technological - capabilities across EU regions to support regional industrial resilience for more distributed and sustainable socio-economic growth and prosperity. - - - 2018-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - United Kingdom - - - MAKERS - - - H2020-MSCA-RISE-2015 - - - 691192 - - - - - UMWELTBUNDESAMT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (UBA GMBH) - SUOMEN YMPARISTOKESKUS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - FORSCHUNGSZENTRUM JULICH GMBH - HELMHOLTZ-ZENTRUM FUER UMWELTFORSCHUNG GMBH - UFZ - THE RESEARCH COMMITTEE OF THE TECHNICAL UNIVERSITY OF CRETE - CONSIGLIO NAZIONALE DELLE RICERCHE - EUROPEJSKIE REGIONALNE CENTRUM EKOHYDROLOGII POLSKIEJ AKADEMII NAUK - UNIVERZITET U NOVOM SADU - SVERIGES LANTBRUKSUNIVERSITET - NATURAL ENVIRONMENT RESEARCH COUNCIL - VLAAMS GEWEST - INSTITUT PO BIORAZNOOBRAZIE I EKOSISTEMNI IZSLEDVANIYA BALGARSKA AKADEMIYA NA NAUKITE - GISAT S.R.O. - HELSINGIN YLIOPISTO - MASINOTEK OY - SENCKENBERG GESELLSCHAFT FUR NATURFORSCHUNG - GEOHIRES INTERNATIONAL GMBH - MAGYAR TUDOMANYOS AKADEMIA OKOLOGIAI KUTATOKOZPONT - BEN-GURION UNIVERSITY OF THE NEGEV - LATVIJAS UNIVERSITATES AGENTURA LATVIJAS UNIVERSITATES BIOLOGIJAS INSTITUTS - RIJKSUNIVERSITEIT GRONINGEN - FUNDACAO DA FACULDADE DE CIENCIAS DA UNIVERSIDADE DE LISBOA FP - UNIVERSITATEA DIN BUCURESTI - INSTITUTE OF LANDSCAPE ECOLOGY OF THE SLOVAK ACADEMY OF SCIENCES - ZNANSTVENORAZISKOVALNI CENTER SLOVENSKE AKADEMIJE ZNANOSTI IN UMETNOSTI - UNIVERSIDAD DE GRANADA - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - BIOSENSE INSTITUTE - RESEARCH AND DEVELOPMENT INSTITUTE FOR INFORMATION TECHNOLOGIES IN BIOSYSTEMS - - - EUR 4 999 138 - - - European Long-Term Ecosystem and socio-ecological Research Infrastructure - - - EUR 4 999 138 - - - Austria - Finland - France - Germany - Germany - Greece - Italy - Poland - Serbia - Sweden - United Kingdom - Belgium - Bulgaria - Czech Republic - Finland - Finland - Germany - Germany - Hungary - Israel - Latvia - Netherlands - Portugal - Romania - Slovakia - Slovenia - Spain - Spain - Serbia - - - Other - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - - A collective effort is needed to create the environmental research infrastructure for answering pressing questions in a world of rapid social, economic and environmental change. - - 2019-05-31, ongoing project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.2."> - - - INFRAIA-1-2014-2015 - Integrating and opening existing national and regional research infrastructures of European interest - - - RIA - Research and Innovation action - - - Austria - - - eLTER - - - H2020-INFRAIA-2014-2015 - - - 654359 - - - - - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - THE UNIVERSITY OF EXETER - WAGENINGEN UNIVERSITY - TECHNISCHE UNIVERSITAET DRESDEN - KOBENHAVNS UNIVERSITET - UNIVERSIDAD DE VALLADOLID - UNIVERSITEIT UTRECHT - FUNDACION CIDAUT - FRIEDRICH-SCHILLER-UNIVERSITAT JENA - UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK - - - EUR 3 896 688,10 - - - Critical Transitions in Complex Systems - - - EUR 3 896 688,10 - - - United Kingdom - United Kingdom - Netherlands - Germany - Denmark - Spain - Netherlands - Spain - Germany - Ireland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Complex systems research has been on the forefront of scientific priorities of many national research councils and the EU for more than a decade. Many very interesting phenomena have been identified and explored, but the - development of the underpinning mathematical theory has been lagging behind. The proposed training network builds on an emerging development in applied mathematics to provide proper mathematical theory for the existence of early-warning signals for - sudden changes in dynamical behaviour, so-called critical transitions, which have been reported by applied scientists in various contexts. Practical implications for the existence of such early-warning signals are far reaching, since these would - enable the development of better control strategies to avoid or diminish the effect of catastrophes. Topical examples include epileptic seizures, stock market collapses, earthquakes, and climate. Attending to the mathematical underpinning for - critical transitions in complex systems, it is apparent that the relevant mathematical discipline of bifurcation theory, that has been developed to great acclaim and use for primarily low-dimensional deterministic autonomous (i.e. intrinsically - time-independent) dynamical systems, and (in the context of phase transitions) for material science, does not apply without nontrivial modification to most of the complex systems contexts. The training network is a response to the needs of applied - scientists (including many in the private sector) for a proper mathematical underpinning of early-warning signals. After their training, the trained researchers will be at the very forefront of this rapidly developing field, with many practical - skills and crucial theoretical insights into the possibilities (and impossibilities) of early-warning signals for critical transitions in a wide range of contexts. - - 2019-03-31, ongoing project | - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - CRITICS - - - H2020-MSCA-ITN-2014 - - - 643073 - - - - - ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM - ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM - - - EUR 1 495 715 - - - Origins of Alzheimer's disease across the life-course - - - EUR 1 495 715 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The origins of Alzheimer’s disease (AD) remain elusive. The long pre-clinical phase of AD is universally recognized, but it is not known when predisposition for AD develops nor when the first signs and symptoms become - discernable. In this regard, an essential role is played by the ‘reserve’ capacity of the brain, which is built up in early life and acts as buffer against adverse risk factors later in life. However, life-time trajectories of build up and loss of - reserve and its determinants remain poorly understood. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - ORACLE - - - ERC-2015-STG - - - 678543 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 185 076 - - - Anderson Transition in a Quantum Gas Signatures and Characterization - - - EUR 185 076 - - - France - - - Research Organisations - - Anderson localization (AL) – an effect arising from interference of multiple-scattering events and leading to a complete halt of transport in disordered media – is a fundamental phenomenon, ubiquitous in all wave physics. - - - 2017-12-31, Grant Agreement terminated - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - AnTraQuGa - - - H2020-MSCA-IF-2014 - - - 655933 - - - - - QUEEN MARY UNIVERSITY OF LONDON - - - EUR 183 454,80 - - - Role of GST gene variation in susceptibility to mercury (Hg)-induced neurodevelopmental disorders (NDD) in zebrafish - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Environmental factors, including the heavy metal mercury, are recognized as having a dominant influence on the aetiology and prevalence of neurodevelopmental behavioural disorders. This proposal will develop a new model for - assessing the role of gene:environment interactions, specifically genetic predisposition for toxicity, in risk for disease, and identify early markers predictive of toxicity and later phenotypes. This will directly relate to the EC work program for - Health, demographic change and wellbeing, with respect to both 'Personalized medicine' for non-communicable diseases and 'Early development' addressing mental health from childhood to older ages. The project uses the zebrafish model to investigate - the relationship between glutathione-S-transferase (GST)-related genetic background, developmental exposure to mercury, and risk for neurodevelopmental disorders. This will be achieved by exposure of wild-type and CRISPR-generated Gst mutant embryos - to mercury, and testing whether genetic predisposition leads to increased risk for toxin-induced behavioural phenotypes. We will test for altered biochemical, transcriptomic and epigenomic modifications that may serve as potential early markers for - insult. The results obtained in this proposal will have significant impact on the ability to conduct individual and population specific toxicity risk assessment, and may lead to novel measures for early detection of increased risk and alleviation of - potential adverse outcomes. The high-quality original research presented in the proposal will not only enable the Experienced Researcher to reach a position of professional maturity in her career, but will also allow her to develop a spectrum of new - and interdisciplinary skills, integrating her previous training and knowledge into the behavioural genetics skills set. This project will also allow Dr. Brennan's group to integrate developmental toxicology into existing behavioural research, and - will generate new collaborations. - - 2019-06-19, ongoing project - - - 2017-06-20 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - GSTHgNDD - - - H2020-MSCA-IF-2015 - - - 705572 - - - - - PERCUROS BV - ACADEMISCH ZIEKENHUIS LEIDEN - UNIVERSITAETSMEDIZIN GOETTINGEN - GEORG-AUGUST-UNIVERSITAET GOETTINGEN - STIFTUNG OEFFENTLICHEN RECHTS - UNIVERSITEIT MAASTRICHT - ITHERA MEDICAL GMBH - TAGWORKS PHARMACEUTICALS BV - RAYFOS LTD - TECHNISCHE UNIVERSITAET MUENCHEN - MAUNA KEA TECHNOLOGIES - GAMMA TECHNOLOGIES LIMITED - ANTIBODIES FOR RESEARCH APPLICATIONS BV - TECOBIOSCIENCES GMBH - ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 2 430 000 - - - Preclinical Intra-Operative Image-Guided Surgery and Post-Operative Radiotherapy of Tumours - - - EUR 2 430 000 - - - Netherlands - Netherlands - Germany - Netherlands - Germany - Netherlands - United Kingdom - Germany - France - United Kingdom - Netherlands - Germany - Netherlands - Germany - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - The main objective and basic concept of our proposal is to improve intra-operative and post-operative targeted surgical probes and new detection systems for surgical intervention of cancer. The work revolves around the - mobility of clinicians, scientists and technologists between twelve consortium partners and across four different countries. The goal is the implementation of inter-disciplinary, inter-sector, cross-training of personnel. As a consequence, this will - serve to accelerate the development of improved imaging technologies and hybrid fluorescence/radionuclide probes for the surgical intervention of cancer. The hypothesis is that if we can develop a hybrid probe for both targeted image-guided surgery - and post-operative molecular radiotherapy, we would be implementing a revolutionary imaging and therapeutic approach for oncology surgeons to help their patients by improving better overall survival and quality of life for the patient. There are four - key objectives within this project: 1) synthesis of a near infra-red fluorescence (NIRF)-dye conjugated to a peptide that is targeted towards a tumour associated antigen, 2) deliver a novel clinical optoacoustic handheld camera to detect the - fluorescence probe in deep tissue, 3) validate the probe/target combination across the subcellular, cellular, endoscopic and macroscopic levels with state-of-art technologies, and 4) develop the probe further by targeting a radionuclide entity to the - fluorescent construct for postoperative radiotherapy. Surgeons would have a more definitive reference for resection, if the tumour margin can be clearly defined. If this can be achieved, the impact would be (a) reduced recurrence rates in patients by - lowering the risk of residual tumour tissue remaining after surgery and as a consequence improve survival, (b) minimised removal of healthy tissues, c) reduced patient morbidity and hospital stay and d) significant health cost benefits. - - 2019-01-31, ongoing project - - - 2015-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Netherlands - - - PRISAR - - - H2020-MSCA-RISE-2014 - - - 644373 - - - - - UNIVERSITE DE BORDEAUX - UNIVERSITE DE BORDEAUX - - - EUR 1 859 413 - - - Unraveling the origin of the Initial Mass Function - - - EUR 1 859 413 - - - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Despite the tremendous progress achieved over the past decade, the study of stellar formation is far from complete. We have not yet measured the minimum mass for star formation, nor the shape of the IMF down to the least - massive free-floating planets, or know how universal this shape is. Although clusters are the building blocks of galaxies, little is known about their early dynamical evolution and dispersal into the field. The main culprit for this state of affairs - is the high level of contamination and incompleteness in the sub-stellar regime, even for the best photometric and astrometric surveys. - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - France - - - COSMIC-DANCE - - - ERC-2015-CoG - - - 682903 - - - - - ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM - ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM - - - EUR 2 000 000 - - - Towards solving myopia: from genes to pathways using an integrated approach - - - EUR 2 000 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Background: - - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - MYOP-PATH - - - ERC-2014-CoG - - - 648268 - - - - - ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM - ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM - - - EUR 150 000 - - - DNA rEpair impaired Mice with accElerated Neurodegeneration as Tool to Improve Alzheimer therapeutics - - - EUR 150 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Alzheimer’s disease (AD) affects worldwide ~50 million people. Preclinical research relies mainly on transgenic mouse models overexpressing mutant human proteins that are altered in <5% of AD cases (e.g. β-amyloid and tau), - however, despite prominent protein aggregates, they fail to show the dramatic neurodegeneration and cognitive decline of patients, indicating that plaques and tangles may not be the only requirement for AD. Age is the most determining factor in AD, - but is poorly represented in current AD models. - - 2016-12-31, closed project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2014 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Netherlands - - - Dementia - - - ERC-2014-PoC - - - 665335 - - - - - ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM - ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM - - - EUR 1 969 586,04 - - - Embryonic origins of cardiovascular health in later life: disentangling early causal pathways in a lifecourse perspective - - - EUR 1 969 586,04 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Children born preterm or with a small size at birth have increased risks of cardiovascular disease and type 2 diabetes in adulthood. These intriguing associations strongly suggest that common diseases have at least part of - their origins in early fetal life. From both an etiological and preventive perspective, it is important to disentangle the early fetal critical periods and causal pathways. An accumulating body of evidence suggests that early pregnancy, or even the - preconception period, may influence the risk of cardiovascular and metabolic disease throughout the lifecourse. The main hypothesis for this project is that adverse exposures before or very early in pregnancy induce embryonic and placental - developmental adaptations, which permanently affect cardiovascular and metabolic development and predispose individuals to both adverse outcomes at birth and cardiovascular and metabolic dysfunction and diseases in later life. I will use an - integrated epidemiological, molecular and clinical full lifecourse approach from preconception to adulthood embedded in three population-based cohort studies. Innovative element are: 1) focus on developmental adaptations during the embryonic phase - and early placentation assessed by advanced imaging studies at 6, 8, 10 and 12 weeks of gestation; (2) detailed cardiovascular and metabolic studies in infancy and late childhood, including 3T MRI of the heart, aorta, liver and abdomen, metabolomics - analyses; and (3) genome-wide DNA-methylation studies to identify specific DNA-methylation changes related to preconception or early pregnancy exposures, which persist in late childhood and adulthood and are associated with cardiovascular and - metabolic outcomes in later life. With these approaches, this project will provide unique and important new perspectives into the earliest origins of cardiovascular disease and type 2 diabetes and will ultimately contribute to development of - preventive strategies focused on future parents and children. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - EMBRYOandLATERHEALTH - - - ERC-2014-CoG - - - 648916 - - - - - UNIVERSITAT AUTONOMA DE BARCELONA - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - PANEPISTIMIO IOANNINON - CHALMERS TEKNISKA HOEGSKOLA AB - LEIBNIZ-INSTITUT FUER FESTKOERPER- UND WERKSTOFFFORSCHUNG DRESDEN E.V. - VILNIAUS UNIVERSITETAS - FAKULTET INZENJERSKIH NAUKA UNIVERZITETA U KRAGUJEVCU - ISTITUTO NAZIONALE DI RICERCA METROLOGICA - Happy Plating GmbH - - - EUR 3 274 969,68 - - - Smart ELECTrodeposited Alloys for environmentally sustainable applications: from advanced protective coatings to micro/nano-robotic platforms - - - EUR 3 274 969,68 - - - Spain - United Kingdom - Greece - Sweden - Germany - Lithuania - Serbia - Italy - Austria - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Paolo Antonio Mastroeni - Tel.: +39-011-3919541 - Fax: +39-011-346384 - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - SELECTA is a highly inter-disciplinary initiative which has the primary goal of training young researchers in the field of smart electrodeposited metallic alloys suitable for environmental / sustainable development - applications. The Network encompasses the fabrication and in-depth characterization of: (i) innovative protective coatings, (ii) resilient micro/nano-electromechanical systems, and (iii) wirelessly actuated micro/nano-robotic platforms for - cutting-edge environmental applications. The project will explore new types of electrodeposited alloys (based on Fe, Cu or Al; free from hazardous and scarce raw elements), with tunable structure (amorphous, nanocrystalline), morphology (dense, - nanoporous) and geometry (films, micropillars, nanowires), to meet specific technological demands (high wear/corrosion resistance, superior magnetic properties or hydrophobicity). SELECTA aims to integrate technological progress with environmental - sustainability concerns, which is one of the major “Societal Challenges” listed in the Horizon 2020 Work Programme. Several disciplines (Physics, Electrochemistry, Engineering, Environmental Sciences, Biology and Robotics) converge together to - provide a holistic approach to accomplish the SELECTA goals. The project brings together 10 Beneficiaries and 7 Partner Organizations (including 5 private companies), belonging to 10 EU Member States (plus Switzerland and Serbia). Special efforts - will be devoted to bridge fundamental science with commercialisation of the research outcome. The complementarities among partners will render a high-level, multi-faceted educational programme. World-class research will be combined with unique - training opportunities in soft skills, such as career planning, dissemination, intellectual property rights, entrepreneurship or management. The Network aims to provide highly-qualified specialists able to face future professional challenges in - either Academia or Industry in an independent manner. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Spain - - - SELECTA - - - H2020-MSCA-ITN-2014 - - - 642642 - - - - - ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM - ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM - - - EUR 149 937 - - - Automated framework for rapid simulations of high-detail brain models - - - EUR 149 937 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Traditional methods of software modeling and simulation take prohibitive amounts of time to run for the size and complexity of biologically realistic neuron populations (e.g. >1 million). For instance, simulation of a 100 - high-detail (Inferior-Olive) neuron-network for 10 minutes of brain time take 42 hours to complete on an modern PC workstation. To tackle this problem - common to the international neuroscience community -, we have turned to hardware-accelerated - simulation platforms. We have employed award-winning, FPGA -based, dataflow machines provided by Maxeler Technologies, which offer high-performance computing capabilities and come with programming tools of unprecedented user friendliness. Our current - Maxeler setups have offered impressive acceleration rates of more than 4 orders of magnitude (x10000). Despite the achieved speeds, however, we have found the Maxeler programming tools to be cumbersome to learn by neuromodelers with little hardware - knowledge. Engineering personnel has, thus, been employed to assist them in (efficiently) translating and deploying their models. To streamline this process and bring a powerful tool directly to the hands of modelers, we propose BrainFrame, a novel - system consisting of Maxeler hardware and a comprehensive software toolflow, effectively adding an abstraction level for neuromodelers to work on without specific knowledge of the underlying simulation platform. BrainFrame comprises a “one-stop - shop”, integrated solution primarily targeting labs and companies active in the field of brain-modeling research and applications. - - 2016-01-31, closed project - - - 2015-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2014 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Netherlands - - - BrainFrame - - - ERC-2014-PoC - - - 641000 - - - - - ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM - - - EUR 165 598,80 - - - Mapping the neuronal representation in dorsal inferior colliculus through optical imaging, stimulus optimization and optogenetics - - - EUR 165 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Despite being the most accessible subcortical auditory structure, little is known about the dorsal cortex (ICd) of the inferior colliculus. Limited physiological evidence hints at functions regarding detection of - frequency-modulation, novel sounds and selective attention. This project tries to address three fundamental questions regarding the ICd, namely: (1) what are optimal stimuli for the neurons in the ICd, (2) why is the neuronal activity in ICd - important for the organism and (3) how does the neuronal circuit achieve the necessary computation. Taking advantage of state-of-the-art in vivo optical imaging, I will search for effective stimulus features through a population-wide stimulus - optimization approach (WP1). The ability to measure neuronal activity over weeks expands the range of sound stimuli researchers can deliver, providing a basis for a more unbiased stimulus search. Moreover, groups of cells that respond to similar - features can be detected, while extra efforts can be diverted towards identifying optimal stimuli for the remaining cells. Secondly, a behavioural paradigm will be developed to probe the effect of selective attention on neuronal activity of the ICd - (WP2). At the same time, comparing neuronal and behavioural response will help us understand how neuronal representations translate into percept and actions of the animal. Finally, I will investigate how neuronal activities in the ICd are shaped by - projections from other brain regions, through the imaging of synaptic terminals from these inputs and, subsequently, optogenetic manipulations. The results will lead to a major understanding in the sensory processing at the auditory midbrain and the - functional significance of its interactions with other brain regions. These research outcomes are not ends in themselves, but will provide the Fellow with a basis for further research as an independent group leader. - - 2017-02-28, closed project - - - 2015-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - OPTIMAPIC - - - H2020-MSCA-IF-2014 - - - 660157 - - - - - PLANETEK ITALIA SRL - PLANETEK HELLAS ETAIREIA PERIORISMENIS EFTHYNIS YPIRESIES CHARTOGRAFISIS MESO DORYFOROU - NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA - TECHNOLOGIKO PANEPISTIMIO KYPROU - University of the Aegean-Research Unit - UNIVERSITA DEGLI STUDI DI BARI ALDO MORO - TWT GMBH SCIENCE & INNOVATION - I-SEA - CLOUDSIGMA AG - - - EUR 1 584 000 - - - Semantic EO Data Web Alert and Retrieval Framework - - - EUR 1 584 000 - - - Italy - Greece - Greece - Cyprus - Greece - Italy - Germany - France - Switzerland - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Technological advances in remote sensing have increased the availability of satellite images with different spatiotemporal and spectral characteristics.There is difficulty for retrieving the most appropriate data for each - user's needs.One key challenge is to connect the quantitative information of the EO images with the qualitative (high-level user queries) and be able to mine these connections in big archives.An inherent question arises; how to retrieve EO images - based on user semantically aware questions.Content based EO image retrieval techniques have been introduced for bridging the gap between low-level image features and high-level queries.The main constraint of the existing approaches is the - generalization of the problem.The formulated ontologies are not focused on the constraints of EO images.The main objective of SEO-DWARF is to realize the content-based search of EO images on an application specific basis.The marine application domain - and data from Sentinels 1,2,3, ENVISAT will be used.Queries such as “Calculate the rate of increasing chlorophyll in the NATURA area” will be answered by the SEO-DWARF, helping users to retrieve the appropriate EO images for their specific needs or - alert them when a specific phenomenon occurs.The research contains the:a) ontology formalization for the specific research topics,b) determination of the semantic queries for the application domains,c) algorithm development for extracting metadata - from the EO images,d) design of an architecture of the platform to perform the semantic image retrieval and storage and management of the extracted metadata.All four aspects will be integrated in an innovative and user-friendly web based platform - enabling the users to retrieve images for marine applications or register for a semantic alert.A strong and experienced research team, of 4 academic and 5 industrial partners, coming from Greece(3), Italy(2), Germany(1), France(1), Cyprus(1) and - Switzerland(1) constitute the project’s consortium. - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Italy - - - SEO-DWARF - - - H2020-MSCA-RISE-2015 - - - 691071 - - - - - ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM - ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM - - - EUR 1 500 000 - - - Cerebellar modules and the Ontogeny of Sensorimotor Integration - - - EUR 1 500 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The perfect execution of a voluntary movement requires the appropriate integration of current bodily state, sensory input and desired outcome. To assure that this motor output becomes and remains appropriate, the brain needs - to learn from the result of previous outputs. The cerebellum plays a central role in sensorimotor integration, yet -despite decades of studies- there is no generally excepted theory for cerebellar functioning. I recently demonstrated that cerebellar - modules, identified based on anatomical connectivity and gene expression, differ distinctly in spike activity properties. It is my long-term goal to identify the ontogeny of anatomical and physiological differences between modules, and their - functional consequences. My hypothesis is that these differences can explain existing controversies, and unify contradicting results into one central theory. - - - 2021-05-31, ongoing project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - COSI - - - ERC-2015-STG - - - 680235 - - - - - ECOLE D'ECONOMIE DE PARIS - ECOLE D'ECONOMIE DE PARIS - - - EUR 1 598 307,50 - - - The Economics of Ethnic Prejudice - - - EUR 1 598 307,50 - - - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Why do ethnic differences matter in some cases and not in others? What determines the strength of ethnic self-identification? This question is central to understanding the consequences of ethnic divisions for conflict and - economic development and their policy implications but it was neglected by economic research until now. This project aims at filling this gap by endogenizing ethnic identity. We study how the salience of ethnic differences depends on economic and - social context and policies of nation building. Our research program is organized around 3 pillars focusing on social, economic, and political determinants of ethnic tensions, respectively. The first pillar tests social psychology theories of ethnic - identity using natural experiments, generated by forced mass movements of ethnic groups in Eastern Europe and from Eastern Europe to Central Asia as a result of WWII. The second pillar studies how market interactions between representatives of - different ethnic groups and, in particular, ethnic occupational segregation affects ethnic tensions in the context of historical anti-Jewish violence following agro-climatic income shocks in the 19th and 20th century Eastern Europe. The third pillar - focuses on the effects of political manipulation on ethnic conflict in the context of the historical experiment of nation building in Central Asia. It studies how political empowerment of a certain ethnic elite in a multi-ethnic traditional society - coupled with a set of nation-building policies affects ethnic conflicts depending on the pre-existing ethnic mix and the distribution of political power among ethnic elites. This research will shed light on factors that make ethnic diversity - important for conflict and economic development. - - 2020-10-31, ongoing project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - France - - - Econ_Prejudice - - - ERC-2014-CoG - - - 646662 - - - - - ISARDSAT SL - UNIVERSITE PAUL SABATIER TOULOUSE III - CENTRO DE ASESORIA DOCTOR FERRER SL - INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT - - - EUR 895 500 - - - Root zone soil moisture Estimates at the daily and agricultural parcel scales for Crop irrigation management and water use impact – a multi-sensor remote sensing approach - - - EUR 895 500 - - - Spain - France - Spain - France - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - - Sustainable water use is a growing concern in Europe. Nowadays, agriculture is an important pressure on water resources especially in Mediterranean countries where irrigation can represent up to 80% of the consumptive uses of - water. Increasing water use efficiency in agriculture has been thus identified as one of the key themes relating to water scarcity and drought (EEA Report No 1/2012). It now becomes necessary to improve on-farm irrigation management by adjusting - irrigation to crop water requirements along the growing season. - - 2019-02-28, ongoing project - - - 2015-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Spain - - - REC - - - H2020-MSCA-RISE-2014 - - - 645642 - - - - - ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - PERCUROS BV - THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN - TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY - CARDIFF UNIVERSITY - UNIVERSITAIR MEDISCH CENTRUM UTRECHT - AO-FORSCHUNGSINSTITUT DAVOS - AARHUS UNIVERSITET - PROCORE LTD - UNIVERSITEIT MAASTRICHT - - - EUR 3 971 459,88 - - - Targeting Cartilage Regeneration in joint and intervertebral disc diseases - - - EUR 3 971 459,88 - - - Netherlands - United Kingdom - Netherlands - United Kingdom - Israel - United Kingdom - Netherlands - Switzerland - Denmark - Israel - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - Mobility, important for well-being, is seriously impaired by chronic low back pain and osteoarthritis in many people due to degeneration of cartilaginous tissue of the intervertebral disc and joint. To develop a treatment for - these diseases this ETN aims to combine expertise in novel highly advanced drug delivery carriers with dedicated targeting tools, state of the art imaging techniques and expertise in stem cell and joint biology by training 15 young scientists in 12 - partner institutes located in 5 different countries. - - 2019-02-28, ongoing project | - - - 2015-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Netherlands - - - TargetCaRe - - - H2020-MSCA-ITN-2014 - - - 642414 - - - - - THE UNIVERSITY OF BIRMINGHAM - POLITECNICO DI MILANO - UNIVERSIDADE DO PORTO - TECHNISCHE UNIVERSITEIT DELFT - KUNGLIGA TEKNISKA HOEGSKOLAN - TTY-SAATIO - NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU - UNIVERSITAT POLITECNICA DE VALENCIA - VYSOKE UCENI TECHNICKE V BRNE - MER MEC FRANCE - ROADSCANNERS OY - EVOLEO TECHNOLOGIES LDA - - - EUR 1 057 500 - - - Rail Infrastructure Systems Engineering Network - - - EUR 1 170 000 - - - United Kingdom - Italy - Portugal - Netherlands - Sweden - Finland - Norway - Spain - Czech Republic - France - Finland - Portugal - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Social and economic growth, security and sustainability in Europe are at risk of being compromised due to aging and failing railway infrastructure systems. This partly reflects a recognised skill shortage in railway - infrastructure engineering. This project, RISEN, aims to enhance knowledge creation and transfer using both international and intersectoral secondment mechanisms among European Advanced Rail Research Universities/SMEs and Non-EU, world-class rail - universities including the University of Illinois at Urbana Champaign (USA), Massachusetts Institute of Technology (USA), Southwest Jiaotong University (China) and University of Wollongong (Australia). This project adds research skill mobility and - innovation dimension to existing bilateral collaborations between universities through research exchange, joint research supervision, summer courses, international training and workshops, and joint development of innovative inventions. It spans over - 4 years from April 2016 to March 2020. - - - 2020-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - United Kingdom - - - RISEN - - - H2020-MSCA-RISE-2015 - - - 691135 - - - - - UNIVERSITA DEGLI STUDI DELL'AQUILA - UNIVERSITY OF NEWCASTLE UPON TYNE - THE UNIVERSITY OF MANCHESTER - ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM - REGION HOVEDSTADEN - - - EUR 607 500 - - - Training network for Research on molecUlar and Biomechanical Interactions in CONnective tissue disorders - - - EUR 877 500 - - - Italy - United Kingdom - United Kingdom - Netherlands - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - RUBICON will establish a global network for staff exchange of scientists and for research training focussed on connective tissue disorders. It will bring together leading scientific groups from 5 European and 5 non-European - countries who will study the molecular and biomechanical factors involved in the pathophysiology of connective tissues, including tendons, cartilage and bone. The ambitious objectives of RUBICON are to increase our knowledge of the mechanisms - underlying diverse connective tissue disorders, identify commonalities and targetable pathways, and reinforce multidisciplinary awareness in this fundamental research field. - - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Italy - - - RUBICON - - - H2020-MSCA-RISE-2015 - - - 690850 - - - - - AGENCIA PER A LA COMPETITIVITAT DE LA EMPRESA - - - EUR 5 097 600 - - - ACCIÓ programme to foster mobility of researchers with a focus in applied research and technology transfer - - - EUR 10 195 200 - - - Spain - - - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - TECNIOspring PLUS Fellowship Programme is proposed by ACCIÓ, the Catalan Agency for Business and Competitiveness, attached to the Ministry for Business and Labour of the Government of Catalonia. - - - 2021-06-30, ongoing project - - - 2016-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2015-FP - Marie Skłodowska-Curie Co-funding of regional, national and international programmes (COFUND-FP) - - - MSCA-COFUND-FP - Fellowship programmes - - - Spain - - - TECNIOspring PLUS - - - H2020-MSCA-COFUND-2015 - - - 712949 - - - - - POLITECHNIKA WARSZAWSKA - INSTITUT JOZEF STEFAN - POLITECHNIKA WROCLAWSKA - SLOVENSKA TISKOVNA AGENCIJA DOO - - - EUR 1 273 500 - - - Reverse EngiNeering of sOcial Information pRocessing - - - EUR 1 314 000 - - - Poland - Slovenia - Poland - Slovenia - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - In today's world, access to information is a decisive factor advancing industry, society and even culture. It is therefore of great importance to understand why and how some information (e.g. some memes) spreads virally with - great ease, while other is met with disinterest and omission. Uncovering the reasons may allow promoting important information, like warnings about cyber-attacks, while stifle harmful rumors, such as vaccines causing autism. The aim of the project is - to treat the vast complexity of such information dynamics in social systems by involving researchers in social sciences, journalism, computing, data mining and complexity science. - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Poland - - - RENOIR - - - H2020-MSCA-RISE-2015 - - - 691152 - - - - - THE HEBREW UNIVERSITY OF JERUSALEM - - - EUR 91 254,60 - - - Smart Markets via Computation - - - EUR 91 254,60 - - - Israel - - - Higher or Secondary Education Establishments - - E-commerce, modern-day government auctions, the sharing economy – these all have in common the optimization of resource allocation through the combination of economics and computation. This trend holds enormous socio-economic - opportunity: for example, it allows online auctions, personalized advertising that supports the internet ecosystem, government repacking of radio spectrum to support growing communication needs, and flexible pricing that reflects true demand. It also - poses an enormous challenge due to the sophisticated treatment of resources it requires, a challenge which theoretical computer science and algorithmic game theory in particular are uniquely positioned to address. - - - 2017-09-30, closed project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Israel - - - SMAC - - - H2020-MSCA-IF-2015 - - - 708935 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - ALBERT-LUDWIGS-UNIVERSITAET FREIBURG - UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA - TECHNISCHE UNIVERSITAET WIEN - UNIVERZA V MARIBORU - KARLSRUHER INSTITUT FUER TECHNOLOGIE - - - EUR 2 012 205,24 - - - Towards Next-generation Eco-efficient PHOTO and EMULSION PolymerisationsImparting Synergy to Process, Products and Applications - - - EUR 2 012 205,24 - - - France - Germany - Germany - Spain - Austria - Slovenia - Germany - - - Research Organisations - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The polymer industry is going through one of the most significant periods of change in its history. Driven by new environmental regulations, the development of eco-efficient processes and zero-VOC products has become an - absolute necessity. In this field, 2 technologies stand out: Polymerisation in dispersed media and Photopolymerisation. To maintain EU leadership in this sector, PHOTO-EMULSION aims at training a creative, entrepreneurial & innovative - next-generation of 8 Early-Stage Researchers (ESRs) who can push towards new eco-friendly polymerisation processes. Our primary strength is a demanding technical knowledge base bringing together, for the first time, all disciplines related to these 2 - strategic fields. Secondly, we will broaden traditional doctoral training by targeting transferable and specialized skills sought after by the employers, and learned through innovative methods: tandem ESRs, distance language learning, ESR as - itinerant science educator, online courses, ESR-led subproject, highly interactive meetings, and industrial secondments. In research, we will develop a “hybrid” next-generation technology based on thiol-ene photopolymerisation in dispersed media. - Advanced manufacturing based on photoreactor promises a wave of high sulfur content dispersed products (films, nanoparticles, porous network). Their outstanding properties open the door to applications responding to current Industral needs such as - non-leaching materials, O2 barrier and biobased waterborne coatings, biologically-active particles, hybrid nanosensors and monolithic chromatography column. PHOTO-EMULSION involves a high-quality research network including 8 internationally reputed - academic institutions, 4 leading companies and 2 non-profit organisations. Balanced & EU-wide, our diversity expresses through the participation of 8 countries (Austria, France, Germany, Ireland, Poland, Slovenia, Sweden & Spain), 50% female - scientists-in-charge, and structures supporting gender equality. - - 2021-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - France - - - PHOTO-EMULSION - - - H2020-MSCA-ITN-2017 - - - 765341 - - - - - THE UNIVERSITY OF SHEFFIELD - ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA - FIN-CERAMICA FAENZA SPA - BUDAI EGESZSEGKOZPONT KFT - ANSYS FRANCE SAS - ADAGOS - AESCULAP AG - - - EUR 1 588 449,60 - - - SPINe: Numerical and Experimental Repair strategies - - - EUR 1 588 449,60 - - - United Kingdom - Italy - Italy - Hungary - France - France - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The SPINNER EID will train a group of Bioengineering early stage researchers to be in a position to design the next generation of repair materials and techniques for spine surgery. SPINNER brings together partners from the - biomaterials (Finceramica), implantable devices (Aesculap), and computational modelling (Ansys, Adagos) industries with orthopaedic clinicians (National Centre for Spinal Disorders, NCSD) and academic experts in cell, tissue and organ scale - biomaterials and medical device testing (Universities of Sheffield and Bologna). All projects will be fully grounded in practical industrial and clinical requirements, where the number of patients requiring complex spine surgery is rapidly expanding, - and the biomedical engineering industry needs suitably trained, innovators to produce economic solutions to support healthy ageing for the people of Europe. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-EID - European Industrial Doctorates - - - United Kingdom - - - SPINNER - - - H2020-MSCA-ITN-2017 - - - 766012 - - - - - KATHOLIEKE UNIVERSITEIT LEUVEN - RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN - UNIVERSITEIT GENT - MONTANUNIVERSITAT LEOBEN - UNIVERSITA DEGLI STUDI DI PADOVA - Eidgenössische Technische Hochschule Zürich - LINKOPINGS UNIVERSITET - KUNGLIGA TEKNISKA HOEGSKOLAN - SHANKS VALORIZATION & QUARRY - ITALCEMENTI FABBRICHE RIUNITE CEMENTO SPA - - - EUR 3 844 721,16 - - - EU Training Network for Resource Recovery through Enhanced Landfill Mining - - - EUR 3 844 721,16 - - - Belgium - Germany - Belgium - Austria - Italy - Switzerland - Sweden - Sweden - Belgium - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Europe has somewhere between 150,000 and 500,000 landfill sites, with an estimated 90% of them being “non-sanitary” landfills, predating the EU Landfill Directive of 1999. These older landfills tend to be filled with municipal - solid waste and often lack any environmental protection technology. In order to avoid future environmental and health problems, many of these landfills will soon require expensive remediation measures. This situation might appear bleak, but it does - present us with an exciting opportunity for a combined resource-recovery and remediation strategy, which will drastically reduce future remediation costs, reclaim valuable land, while at the same time unlocking billions of tonnes of valuable - resources contained within these landfills. However, the widespread adoption of Enhanced Landfill Mining (ELFM) in the EU, as envisaged by NEW-MINE, urgently requires skilled scientists, engineers, economists and policy makers who can develop - cost-effective, environmentally friendly ELFM practices and regulatory frameworks. All this demands a European commitment to concerted, inter- and transdisciplinary research and innovation. The NEW-MINE project trains 15 early-stage researchers - (ESRs) in all the aspects of landfill mining, in terms of both technological innovation and multi-criteria assessments for ELFM. The technological innovation follows a value-chain approach, from advanced landfill exploration, mechanical processing, - plasma/solar/hybrid thermochemical conversion and upcycling, while the multi-criteria assessment methods allow the ESRs to compare combined resource-recovery/remediation ELFM methods with the “Do-Nothing”, “Classic remediation” and “Classic landfill - mining with (co-)incineration” scenarios. By training the ESRs in scientific, technical and a range of soft skills, all based on a collaboration involving EU-leading institutes, they become highly sought-after scientists and engineers for the rapidly - emerging ELFM and recycling industries. - - 2020-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Belgium - - - NEW-MINE - - - H2020-MSCA-ITN-2016 - - - 721185 - - - - - EUROPEAN VACCINE INITIATIVE - EEIG - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - Statens Serum Institut - SCLAVO VACCINE ASSOCIATION - ACADEMISCH ZIEKENHUIS LEIDEN - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - STICHTING WAGENINGEN RESEARCH - ECRIN EUROPEAN CLINICAL RESEARCH INFRASTRUCTURE NETWORK - EATRIS ERIC - VACCINE FORMULATION INSTITUTE LIMITED - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - INSTITUTO DE BIOLOGIA EXPERIMENTAL E TECNOLOGICA - GENIBET - BIOPHARMACEUTICALS SA - HELMHOLTZ-ZENTRUM FUER INFEKTIONSFORSCHUNG GMBH - Foundation BIOMEDICAL PRIMATE RESEARCH CENTRE - LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE - Department of Health - MINISTERIE VAN VOLKSGEZONDHEID, WELZIJN EN SPORT - INSTITUT DE RECERCA I TECNOLOGIA AGROALIMENTARIES - Eidgenössische Technische Hochschule Zürich - UNIVERSITE DE LAUSANNE - UNIVERSITA' DEGLI STUDI DI SIENA - UNIVERSITEIT LEIDEN - INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE - INSTRUCT ACADEMIC SERVICES LIMITED - BIOASTER FONDATION DE COOPERATION SCIENTIFIQUE - - - EUR 10 599 993 - - - European Vaccine Research and Development Infrastructure - - - EUR 10 599 993 - - - Germany - Germany - Denmark - Italy - Netherlands - France - Netherlands - France - Netherlands - United Kingdom - United Kingdom - Portugal - Portugal - Germany - Netherlands - United Kingdom - United Kingdom - Netherlands - Spain - Switzerland - Switzerland - Italy - Netherlands - France - United Kingdom - France - - - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Other - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Other - Research Organisations - - TRANSVAC2 is the follow-up project to its successful predecessor project TRANSVAC, the European Network of Vaccine Research and Development funded under FP7. The TRANSVAC2 consortium comprises a comprehensive collection of - leading European institutions that propose to further advance with the previous initiative towards the establishment of a fully operational and sustainable European vaccine R&D infrastructure. TRANSVAC2 will support innovation for both - prophylactic and therapeutic vaccine development based on a disease-overarching and one-health approach, thereby optimising the knowledge and expertise gained during the development of both human and animal vaccines. This will be achieved by bridging - the translational gap in biomedical research, and by supporting cooperation between public vaccine R&D institutions of excellence, related initiatives and networks in Europe, and industrial partners. TRANSVAC2 will complement and integrate with - existing European research infrastructures in both the public and private sectors. TRANSVAC2 will function as leverage and innovation catalyst between all stakeholders involved in vaccine R&D in Europe and -by providing integrated and overarching - vaccine R&D services- will contribute to the development of effective products to address European and global health challenges, to controlling the burden and spread of infectious diseases, and reinforce the economic assets represented by vaccine - developers in Europe. - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.2."> - - - INFRAIA-01-2016-2017 - Integrating Activities for Advanced Communities - - - RIA - Research and Innovation action - - - Germany - - - TRANSVAC2 - - - H2020-INFRAIA-2016-1 - - - 730964 - - - - - TECHNISCHE UNIVERSITEIT EINDHOVEN - ABB SCHWEIZ AG - - - EUR 510 748,56 - - - Advanced Solid State Transformers - - - EUR 510 748,56 - - - Netherlands - Switzerland - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - ASSTRA is an interdisciplinary training and research project that targets the development of advanced solid state transformer technology which enables a sustainable and flexible (‘Smart’), DC-equipped energy supply system with - a large share of renewable energy sources. This futuristic electrification network has in its core a flexible power conversion unit, distributing electrical energy from sources to loads in a similar fashion as today’s internet hubs distribute - information from senders to receivers. Specifically, this power conversion unit integrates state-of-the-art technology, such as Silicon-Carbide, in order to implement power electronics building blocks and magnetic components featuring breaking - through performances, which will ultimately enable its industrial deployment. - - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-EID - European Industrial Doctorates - - - Netherlands - - - ASSTRA - - - H2020-MSCA-ITN-2017 - - - 765774 - - - - - STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN - - - EUR 165 598,80 - - - Parton Dynamics in QCD Hadron Structure: collinear FFs and unpolarized TMDs - - - EUR 165 598,80 - - - Netherlands - - - Research Organisations - - This project is about the understanding of the structure and dynamics of hadrons in terms of their partonic constituents, quarks and gluons. The aim of this project is to achieve a state-of-the-art determination of collinear - fragmentation functions (FFs) of charged pions and kaons, and of unpolarized transverse-momentum-dependent parton distribution functions (TMDs) of the proton. Cutting-edge statistical and computational tools, previously developed for a determination - of collinear parton distribution functions (PDFs), will be generalized and used in conjunction with all the experimental information currently available. The results obtained on the one hand will provide precision tools for phenomenological studies - in hadron-particle and high-energy collider physics, and on the other hand will improve the knowledge of nucleon structure and hadronization. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - ParDHonS_FFs.TMDs - - - H2020-MSCA-IF-2016 - - - 752748 - - - - - CENTRE TECNOLOGIC DE TELECOMUNICACIONS DE CATALUNYA - ALCATEL-LUCENT DEUTSCHLAND AG - - - EUR 495 745,92 - - - Future Optical Networks for Innovation, Research and Experimentation - - - EUR 495 745,92 - - - Spain - Germany - - - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Future (5G) services will impose stringent requirements in the design and operation of transport networks: increased capacity, low latency, high availability and dynamicity, reduced service provisioning with lower OpEx, while - considering end-to-end service objectives (QoS and QoT). - - - 2021-03-31, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-EID - European Industrial Doctorates - - - Spain - - - ONFIRE - - - H2020-MSCA-ITN-2017 - - - 765275 - - - - - UNIVERSITA CA' FOSCARI VENEZIA - - - EUR 180 277,20 - - - Reader, Author, Scholar in a Context of Information Overflow.How to master and manage knowledge when there is too much to know? - - - EUR 180 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - The Mamluk period (1250-1517) is an example in terms of intellectual vivacity. Scholars and books travel easily, ideas are extensively discussed and shared, and the sum of knowledge available is always increasing. When it is - no longer possible to master all the knowledge alone, and by heart, how do scholars compose new books? - - 2020-01-14, ongoing project - - - 2018-01-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - RASCIO - - - H2020-MSCA-IF-2016 - - - 749180 - - - - - ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM - - - EUR 165 598,80 - - - Biomechanical Characterization of Carotid Plaque Rupture - - - EUR 165 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Stroke is the second leading cause of mortality worldwide. Most stroke events are triggered by an atherosclerotic plaque rupture in a carotid artery. Current clinical decisions for the carotid plaque removal surgery are made - without assessing the plaque rupture risk as no reliable means exists today. Biomechanics can help to develop such risk assessment tools; yet, the fundamental knowledge on biomechanical descriptors of plaque rupture is missing. - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Netherlands - - - BIO-CAPTURE - - - H2020-MSCA-IF-2016 - - - 749283 - - - - - OXFORD BROOKES UNIVERSITY - - - EUR 255 349,80 - - - Social Sustainability and Urban Regeneration Governance: An International Perspective - - - EUR 255 349,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The aim of the research is to support the career development of an experienced researcher through an interdisciplinary project that tackles a crucial policy issue for cities globally, that of urban regeneration governance. - Developing a novel interdisciplinary conceptual framework, and applying a stakeholder evaluative frame in the analysis, the project explores the governance of urban regeneration projects in two world cities, Vancouver and London. - - 2020-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - SURGE - - - H2020-MSCA-IF-2016 - - - 749154 - - - - - UNIVERSITA DEGLI STUDI DI BRESCIA - UNIVERSITA DEGLI STUDI DI BRESCIA - - - EUR 2 084 180,82 - - - Spatiotemporal multimode complex optical systems - - - EUR 2 084 180,82 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The STEMS project is about exploiting the new concept that has been recently introduced by the PI and his co-workers, namely the self-control of the spatial coherence of optical beams in multimode nonlinear optical fibers. - This concept will enable a breakthrough technology, capable of delivering high-energy optical pulses with high-average powers and much higher beam quality from fiber lasers than what is possible today. High-power fiber lasers are largely limited by - transverse mode instabilities, and the loss of spatial coherence in delivery fibers. Optical fibers provide the backbone of today’s internet communication networks, and enable compact, low cost light sources for a variety of industrial and biomedical - applications. In most of these applications, single-mode fibers are used. Replacing single-mode fibers with multimode fibers leads to a dramatic growth of transmission capacity, and a substantial increase of average power and pulse energy from fiber - lasers. However, because of spatial dispersion and resulting mode interference, multimode fibers suffer from an inherent randomization of the spatial transverse beam profile, leading to a loss of spatial coherence. My approach is to exploit the - intensity dependent refractive index, or Kerr nonlinearity, of glass fibers to recover the spatial coherence of a multimode wave, and compensate for temporal modal dispersion. - - 2022-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Italy - - - STEMS - - - ERC-2016-ADG - - - 740355 - - - - - VA-Q-TEC AG - - - EUR 159 460,80 - - - Thermally efficient, cost-reduced nanostructured foams for vacuum insulation panels - - - EUR 159 460,80 - - - Germany - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Climate change is an energy problem, says the conclusion of studies related to global warming. Aware of this “inconvenient truth”, Europe launched strategies, with precise energy savings and gas emissions reductions, to be - reached by 2020 and an ultimate sustainable energy system by 2050. As a large share of energy consumption is spent by the household sector (heating, air conditioning, refrigeration), advanced thermal insulation products give a crucial contribution to - better energy efficiency. - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-SE - Society and Enterprise panel - - - Germany - - - THEcore - - - H2020-MSCA-IF-2016 - - - 748256 - - - - - UNIVERSITY COLLEGE LONDON - - - EUR 183 454,80 - - - Atomistic Electrodynamics-Quantum Mechanical Framework for Characterizing, Manipulating and Optimizing Nonlinear Optical Processes in 2D Materials - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Two-dimensional (2D) materials, which include graphene, phosphorene, and transition metal dichalcogenides monolayers, exhibit extraordinary linear and nonlinear optical properties not attainable in bulk media. They find - tremendous potentials in many photonic and optoelectronic applications, such as all-optical signal processing, optical amplification, nonlinear switching, optical microscopy, quantum detection, and sensing. The availability of first-principle, fast, - efficient computer codes is a prerequisite to the bottom-up design of 2D materials. However, theoretical modeling of 2D materials faces great challenges as it needs to incorporate effects of finite size, edge truncation, periodic modulation, - nonlocal, and quantum confinement. Here, we aim at developing atomistic electrodynamics-quantum mechanical theoretical models and implementing them in high-performance computing (HPC) software for characterizing, manipulating, and optimizing - nonlinear optical processes (NOP) in 2D materials. The main objectives of this ambitious project are: (1) To develop a macroscopic electrodynamics approach for simulating NOP in 2D materials. (2) To develop an atomistic electrodynamics quantum - mechanical framework for modeling NOP in 2D materials and compare the atomistic model to the macroscopic approach. (3) To develop user-friendly and reliable HPC software that seamlessly integrates and implements the theoretical models. (4) Using the - software and theoretical models, emerging applications of 2D materials will be investigated, including solar cells, nonlinear microscopy, and biosensing. The project will have high impacts on: (1) advances in the science, technology, and industry of - UK and Europe; (2) applicant’s future career development; (3) research, industrial, and transferrable knowledge exchange between the host and applicant; (4) design and commercialization of 2D material enabled devices; (5) training of students and - researchers in several interdisciplinary disciplines. - - 2020-01-14, ongoing project - - - 2018-01-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ELECTROQUANTUM-2D - - - H2020-MSCA-IF-2016 - - - 752898 - - - - - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - - - EUR 173 076 - - - Boosting Reward-based Attention through VEstibular STimulation - - - EUR 173 076 - - - France - - - Research Organisations - - Intrinsically rewarding stimuli strongly favour attentional capture (AC) in humans, this effect being dramatic in a number of addiction disorders. The physiology of this phenomenon is poorly understood, but recent neuroimaging - studies point to a role of the Anterior Cingulate Cortex (aCC) in this kind of attentional engagement. A way to act on this circuitry would provide compelling evidence and be a major advance for the cognitive and clinical neuroscience of motivation. - - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - BRAVEST - - - H2020-MSCA-IF-2016 - - - 746154 - - - - - UNIVERSITE DE NEUCHATEL - UNIVERSITE DE NEUCHATEL - - - EUR 150 000 - - - Ultrastable optical frequency comb systems - - - EUR 150 000 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The invention of optical frequency combs revolutionized numerous fields in metrology and was honoured by the 2005 Nobel Prize in Physics. Frequency combs have many new emerging applications in optical telecommunications, - broadband high-precision spectroscopy and sensing, etc. Monitoring of environmentally relevant gases and pollutants, medical sensing of biomarkers in human breath, or remote sensing of gases relevant for resources exploitation or farming are - important areas, in which frequency comb systems might find large applications in the future. However, so far, frequency comb systems are mainly used in basic research, despite their large potential for commercial applications. New technology - solutions are required to enlarge the application range of this technology and make it accessible for real-world systems. - - 2018-03-31, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Switzerland - - - ULTRASTABLE - - - ERC-2016-PoC - - - 727493 - - - - - INTERNATIONALES INSTITUT FUER ANGEWANDTE SYSTEMANALYSE - INTERNATIONALES INSTITUT FUER ANGEWANDTE SYSTEMANALYSE - - - EUR 1 819 250 - - - The Demography of Sustainable Human Wellbeing - - - EUR 1 819 250 - - - Austria - Austria - - - Research Organisations - Research Organisations - - This project will apply two distinctly demographic concepts to research questions that go far beyond demography. The wellbeing indicators proposed here will be based on life table methods and the recently operationalized - concept of Demographic Metabolism – modelling social change through the replacement of generations – will be used to get a quantitative analytical handle on the temporal dynamics of improving human wellbeing. - - - 2022-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Austria - - - EmpoweredLifeYears - - - ERC-2016-ADG - - - 741105 - - - - - HELSINGIN YLIOPISTO - HELSINGIN YLIOPISTO - - - EUR 2 500 000 - - - Age at maturity in Atlantic salmon: molecular and ecological dissection of an adaptive trait - - - EUR 2 500 000 - - - Finland - Finland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Life history is the nexus of biology, because various biological questions ultimately revolve around the causes and consequences of variation in reproduction and survival, i.e. fitness. Traditionally, a major tool in - life-history research has been quantitative genetics because it provides an important statistical link between phenotype and genotype. However, the mechanisms by which evolution occurs may remain unclear unless such traditional approaches are - combined with molecular investigations. Another complicating factor is that the fitness of male vs female life histories do not always align, and hence life history traits may be shaped by sexual conflict. This is why life-history approaches focusing - on both quantifying the conflict and understanding its resolution at the genetic level are needed. - - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Finland - - - MATURATION - - - ERC-2016-ADG - - - 742312 - - - - - THE UNIVERSITY OF BIRMINGHAM - SILIXA LTD - RS HYDRO LTD - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - NATURALEA CONSERVACIO, SL - LUXEMBOURG INSTITUTE OF SCIENCE AND TECHNOLOGY - SVERIGES LANTBRUKSUNIVERSITET - FORSCHUNGSVERBUND BERLIN EV - HELMHOLTZ ZENTRUM POTSDAM DEUTSCHESGEOFORSCHUNGSZENTRUM GFZ - HYDRORESEARCH SAM JOHANSSON AB - UVDYNE LIMITED - ISARDSAT SL - EVVOS SA - SETUR - INGENIERIE - AUDIT - CONSEIL - - - EUR 2 115 000 - - - Smart high-frequency environmental sensor networks for quantifying nonlinear hydrological process dynamics across spatial scales - - - EUR 2 335 500 - - - United Kingdom - United Kingdom - United Kingdom - France - Spain - Spain - Luxembourg - Sweden - Germany - Germany - Sweden - United Kingdom - Spain - Luxembourg - France - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Regulators and industries are challenged by the difficulty to analyse and predict the impact of nonlinear environmental processes on short-term and long-term responses of ecosystems to environmental change. Until very - recently, the development of most conventional monitoring, forecasting and prediction tools has been based on the assumption of stationary environmental systems. In the context of global change these tools are increasingly pushed towards and even - beyond their design limits (the latter resulting in the first line from the prevailing limitations in spatial and temporal resolution of environmental observations). - - 2020-11-30, ongoing project - - - 2016-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - United Kingdom - - - HiFreq - - - H2020-MSCA-RISE-2016 - - - 734317 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - FORSCHUNGSZENTRUM JULICH GMBH - HELMHOLTZ-ZENTRUM FUER UMWELTFORSCHUNG GMBH - UFZ - UNIVERSITE DE LIEGE - EBERHARD KARLS UNIVERSITAET TUEBINGEN - KOBENHAVNS UNIVERSITET - UNIVERSITE DE LAUSANNE - UNIVERSITE DE NEUCHATEL - MUQUANS - ITASCA CONSULTANTS - - - EUR 3 865 769,64 - - - European training Network for In situ imaGing of dynaMic processes in heterogeneous subsurfAce environments - - - EUR 3 865 769,64 - - - France - Spain - Germany - Germany - Belgium - Germany - Denmark - Switzerland - Switzerland - France - France - - - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The ENIGMA network will train a new generation of young researchers in the development of innovative sensors, field survey techniques and inverse modelling approaches. This will enhance our ability to understand and monitor - dynamic subsurface processes that are key to the protection and sustainable use of water resources. ENIGMA focuses mainly on critical zone observation, but the anticipated technological developments and scientific findings will also contribute to - monitor and model the environmental footprint of an increasing range of subsurface activities, including large-scale water abstraction and storage, enhanced geothermal systems and subsurface waste and carbon storage. While many subsurface structure - imaging methods are now mature and broadly used in research and practice, our ability to resolve and monitor subsurface fluxes and processes, including solute transport, heat transfer and biochemical reactions, is much more limited. The shift from - classical structure characterization to dynamic process imaging, driven by ENIGMA, will require the development of multi-scale hydrogeophysical methods with adequate sensitivity, spatial and temporal resolution, and novel inverse modelling concepts. - For this, ENIGMA will gather (i) world-leading academic teams and emerging companies that develop innovative sensors and hydrogeophysical inversion methods, (ii) experts in subsurface process upscaling and modelling, and (iii) highly instrumented - field infrastructures for in-situ experimentation and validation. ENIGMA will thus create a creative and entrepreneurial environment for trainees to develop integrated approaches to water management with interdisciplinary field-sensing methods and - novel modelling techniques. ENIGMA will foster EU and international cooperation in the water area by creating new links between hydrogeological observatories, academic research groups, innovative industries and water managers for high-level - scientific and professional training. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - France - - - ENIGMA - - - H2020-MSCA-ITN-2016 - - - 722028 - - - - - KOBENHAVNS UNIVERSITET - - - EUR 200 194,80 - - - Genomic and proteomic analysis of Palaeolithic, Neolithic and Bronze Age humans from Central-Southern Italy - - - EUR 200 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - This project aims at reconstructing the ancestry and oral disease of Palaeolithic, Neolithic and Bronze Age anatomically modern humans from Central-Southern Italy, using genome-wide profiling and mass spectrometry-based - proteomic analysis of skeletal remains and mineralised dental plaque (archaeological dental calculus). In Europe, the transition from hunter-gatherer to agricultural communities (Neolithisation) and the Bronze Age migration into Central Europe from - the Asian steppe were the most important demographic events since the initial peopling by anatomically modern humans. However, until now, no Palaeolithic and only a few of Neolithic and Bronze age individuals from South Europe have been characterised - for genomic analysis. As a consequence, the genetic base of outstanding peopling and migratory processes in prehistoric Europe, such as: (a) the East-West population structure among European hunter-gatherers, and (b) the Neolithic Southern European - horizon known as the Cardial culture, still need to be fully understood. Similarly, metagenomic analysis of Palaeolithic and Neolithic dental calculus has been limited to preliminary screening of a limited number of samples, with no associated - metaproteomic analysis. What taxonomic groups and metabolic functions were lost or gained with Neolithisation? How this affected oral heath? The genomic characterisation of Palaeolithic, Neolithic and Bronze Age humans from Southern Europe will be - integrated with a metagenomic and metaproteomic analysis of dental calculus to produce the richest possible personal “-omics” profiling so far achievable for ancient humans. The two main research objectives are: 1. Integrate Palaeolithic, Neolithic - and Bronze Age human genomic data from Central-Southern Italy within the genomic landscape available for all ancient and present-day West Eurasians, and 2. Reconstruct the oral microbiome, and its metabolic interactions with the host, before and - after Neolithisation. - - 2019-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - PALAEO-ENEO - - - H2020-MSCA-IF-2016 - - - 751349 - - - - - UNIVERSITY OF GLASGOW - UNIVERSITY OF NEWCASTLE UPON TYNE - THE QUEEN'S UNIVERSITY OF BELFAST - TURUN YLIOPISTO - ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM - MOSAIQUES DIAGNOSTICS GMBH - IDRYMA IATROVIOLOGIKON EREUNON AKADEMIAS ATHINON - TAMPEREEN YLIOPISTO - GenomeScan B.V. - ALMAC DIAGNOSTICS LIMITED - - - EUR 2 629 315,80 - - - Translational Research Network in Prostate Cancer - - - EUR 2 629 315,80 - - - United Kingdom - United Kingdom - United Kingdom - Finland - Netherlands - Germany - Greece - Finland - Netherlands - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The Translational Research Network for Prostate Cancer (TransPot) program adopts an innovative, multidisciplinary approach, providing highly sought-after, effective solutions for incurable prostate cancer (PC). - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - TransPot - - - H2020-MSCA-ITN-2016 - - - 721746 - - - - - UNIVERSITAT DE BARCELONA - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - UNIVERSITE DE NEUCHATEL - THE UNIVERSITY OF STIRLING - STOCKHOLMS UNIVERSITET - THE UNIVERSITY OF EDINBURGH - ECOLE NORMALE SUPERIEURE - - - EUR 3 670 853,76 - - - Diaphora: Philosophical Problems, Resilience and Persistent Disagreement - - - EUR 3 670 853,76 - - - Spain - Germany - Switzerland - United Kingdom - Sweden - United Kingdom - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - DIAPHORA serves as a European research and training platform for collaborative research on the nature of philosophical problems, their resilience and the sources of persistent divergence of expert opinion about them, and their - relation to conflicts in the practical sphere. More specifically, DIAPHORA’s 3 principal research objectives are (A) to diagnose what makes philosophical problems so resilient and to clarify to what extent the sustained lack of convergence in - philosophy can successfully be explained by the hardness of its problems; (B) to explain why the tendency has not been towards a general agnosticism about candidate solutions, but rather towards divergence, and to identify features of philosophical - method that allow for such persistent peer disagreement; and (C) to explore whether the dynamics of philosophical debate, despite the subject’s highly theoretical nature, bears important and instructive resemblances to the dynamics of debates about - more practical matters and their political and socio-economical antecedents – and hence whether philosophical problems and their attempted resolution can illuminate, and be illuminated by, the procedural and methodological difficulties besetting - strategies for the adjudication of public affairs, thereby determining what philosophical thought might contribute to society at large. DIAPHORA joins 7 leading European research centres in philosophy, and 5 partner organisations, 3 of which from the - non-academic sector, in the fields of international conflict management, mediation and policy-making, as well as the analysis of social conflict and cultural diversity. It undertakes to provide 14 Early Stage Researchers with the knowledge and skills - necessary to meet the demands of top-level research within its remit, as well as professional complementary skills training in both the academic and non-academic sectors, with the goal of widening their potential societal contributions and improving - their individual career prospects. - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Spain - - - DIAPHORA - - - H2020-MSCA-ITN-2015 - - - 675415 - - - - - HELSINGIN YLIOPISTO - INTEGRATED CARBON OBSERVATION SYSTEM EUROPEAN RESEARCH INFRASTRUCTURE CONSORTIUM - PIN SOC.CONS. A R.L. - SERVIZI DIDATTICI E SCIENTIFICI PER L UNIVERSITA DI FIRENZE - EUROPEAN SOCIAL SURVEY EUROPEAN RESEARCH INFRASTRUCTURE CONSORTIUM - CESSDA AS - ECRIN EUROPEAN CLINICAL RESEARCH INFRASTRUCTURE NETWORK - STICHTING ASTRON, NETHERLANDS INSTITUTE FOR RADIO ASTRONOMY - INSTITUT MAX VON LAUE - PAUL LANGEVIN - STICHTING EGI - AGENZIA PER LA PROMOZIONE DELLA RICERCA EUROPEA - TURUN YLIOPISTO - - - EUR 1 999 867,50 - - - European Research Infrastructures in the International Landscape - - - EUR 1 999 867,50 - - - Finland - Finland - Italy - United Kingdom - Norway - France - Netherlands - France - Netherlands - Italy - Finland - - - Higher or Secondary Education Establishments - Other - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Research Organisations - Research Organisations - Other - Research Organisations - Higher or Secondary Education Establishments - - RISCAPE will provide systematic, focused, high quality, comprehensive, consistent and peer-reviewed international landscape analysis report on the position and complementarities of the major European research infrastructures - in the international research infrastructure landscape. - - - 2019-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.3.1., H2020-EU.1.4.3.2."> - - - INFRASUPP-01-2016 - Policy and international cooperation measures for research infrastructures - - - CSA - Coordination and support action - - - Finland - - - RISCAPE - - - H2020-INFRASUPP-2016-1 - - - 730974 - - - - - THE UNIVERSITY OF SHEFFIELD - FUNDACION PARA LA INVESTIGACION BIOMEDICA DEL HOSPITAL UNIVERSITARIO CLINICO SAN CARLOS - HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH - UNIVERSITE DE NANTES - QUEEN MARY UNIVERSITY OF LONDON - ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOCIENCIAS - UNIVERSITAIR MEDISCH CENTRUM UTRECHT - UNIVERSIDADE DA BEIRA INTERIOR - SEQOMICS BIOTECHNOLOGIA KORLATOLT FELELOSSEGU TARSASAG - INTELLIGENT PHARMA SL - - - EUR 3 818 970,36 - - - Tribbles Research and Innovation Network - - - EUR 3 818 970,36 - - - United Kingdom - Spain - Germany - France - United Kingdom - Spain - Netherlands - Portugal - Hungary - Spain - - - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - This proposal was developed in the context of the medical need to tackle the clinical consequences of obesity-related diseases more holistically. Dysregulation of common molecular pathways that govern the physiological - functioning of adipocytes, immune cells and prostate epithelium cells have been reported in immuno-metabolic disease (such as obesity) and several cancers. The individual projects described in the proposal will investigate regulators of these - pathways with a focus on a recently described family of pseudokinases, namely tribbles proteins, which have a key role in controlling immunity, metabolism and cancer, and which here will serve as prototypical examples for integrative metabolocentric - cancer research. Tribbles are envisaged to contribute directly to the development and progression of prostate cancer, the prognosis of which is substantially worsened in individuals with immuno-metabolic disease. - - 2020-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - TRAIN - - - H2020-MSCA-ITN-2016 - - - 721532 - - - - - KOBENHAVNS UNIVERSITET - - - EUR 200 194,80 - - - Effects of common European tree species on interactions between C and N processes in soil and soil biota - - - EUR 200 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - One of the greatest challenges of the 21st century is to mitigate global climate changes caused by increasing emissions of greenhouse gases. Since soils constitute a larger carbon (C) pool than the vegetation and atmosphere - together an important strategy could be to sequester more C in soils. Plant-soil interactions play an important role for ecosystem services such as C sequestration and N retention in soil and such interactions receive increasing attention among - scientists and policymakers. Novel techniques such as next generation sequencing methods in combination with analysis of C stock patterns under different tree species present an opportunity to highlight complex processes and mechanisms which underlie - C and N fluxes in soil. The proposed research is designed to (1) explore litter-mediated effects of common European tree species on C and N turnover in soil, (2) characterize effects of tree species on community structure and composition of soil - biota, (3) evaluate the impact of common European tree species on metabolic diversity and structure and composition of functional genes related to C and N turnover: and finally, (4) to synthesize the role of soil biota for C and N turnover in soils. - The research will be carried out within a unique common garden experiment with monoculture stands of six common European tree species; the broadleaves beech (Fagus sylvatica L.), pedunculate oak (Quercus robur L.), lime (Tilia cordata L.), sycamore - maple (Acer pseudoplatanus L.) and ash (Fraxinus excelsior L.) and the conifer Norway spruce (Picea abies (L.) Karst.). The proposed Marie-Curie fellowship is promising to highlight impacts of common European trees on complex interactions among soil - microbiota and soil fauna and highlights their role for C and N stocks and fluxes. Results obtained from this research will contribute to bridge gaps in ecological theory in term of ecosystem functions and services. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - AFOREST - - - H2020-MSCA-IF-2016 - - - 747824 - - - - - KOBENHAVNS UNIVERSITET - - - EUR 200 194,80 - - - Paleoproteomics for cultural heritage conservation: biomolecular analysis of ancient Egyptian paint binders - - - EUR 200 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - This project aims to identify the biological species of origin, as well as molecular damage, of proteins used as binding media in ancient Egypt painted artifacts and architecture specimens dating 3000 BC - 600 AD by applying - mass spectrometry-based proteomic strategies. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - EGYPTOMICS - - - H2020-MSCA-IF-2016 - - - 750270 - - - - - INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE - STICHTING WAGENINGEN RESEARCH - FRIEDRICH LOEFFLER INSTITUT - BUNDESFORSCHUNGSINSTITUT FUER TIERGESUNDHEIT - THE PIRBRIGHT INSTITUTE LBG - THE SECRETARY OF STATE FOR ENVIRONMENT, FOOD AND RURAL AFFAIRS - MOREDUN RESEARCH INSTITUTE - INSTITUTO NACIONAL DE INVESTIGACIONY TECHNOLOGIA AGRARIA Y ALIMENTARIA OA MP - INSTITUT DE RECERCA I TECNOLOGIA AGROALIMENTARIES - EIDGENOESSISCHES DEPARTEMENT DES INNERN - PANSTWOWY INSTYTUT WETERYNARYJNY - PANSTWOWY INSTYTUT BADAWCZY - MARINE SCOTLAND - AARHUS UNIVERSITET - AGENCE NATIONALE DE SECURITE SANITAIRE DE L'ALIMENTATION, DE L'ENVIRONNEMENT ET DU TRAVAIL - THE UNIVERSITY OF EDINBURGH - ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM - ISTITUTO ZOOPROFILATTICO SPERIMENTALE DELLE VENEZIE - THE UNIVERSITY OF NOTTINGHAM - UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN - International Livestock Research Institute - COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION - FEDERAZIONE EUROPEA DI ZOOTECNICA - InSCREENeX GmbH - Leica Microsystems CMS GmbH - NOLDUS INFORMATION TECHNOLOGY BV - EPIBIOSAFE LTD - VERTEBRATE ANTIBODIES LIMITED - INMUNOLOGIA Y GENETICA APLICADA SA - INRA TRANSFERT S.A. - - - EUR 9 999 140,50 - - - Veterinary Biocontained facility Network for excellence in animal infectiology research and experimentation - - - EUR 10 017 890,50 - - - France - Netherlands - Germany - United Kingdom - United Kingdom - United Kingdom - Spain - Spain - Switzerland - Poland - United Kingdom - Denmark - France - United Kingdom - Netherlands - Italy - United Kingdom - Ireland - Kenya - Australia - Italy - Germany - Germany - Netherlands - United Kingdom - United Kingdom - Spain - France - - - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Research Organisations - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - VetBioNet seeks to complement and strengthen the present European capacity and competence to meet the challenges of (re)emerging infectious diseases by establishing a comprehensive network of pre-eminent European BSL3 - infrastructures, international organisations, and industry partners that is dedicated to advance research on epizootic and zoonotic diseases and to promote technological developments. - - - 2022-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.2."> - - - INFRAIA-01-2016-2017 - Integrating Activities for Advanced Communities - - - RIA - Research and Innovation action - - - France - - - VetBioNet - - - H2020-INFRAIA-2016-1 - - - 731014 - - - - - CONSIGLIO NAZIONALE DELLE RICERCHE - - - EUR 180 277,20 - - - Photosynthetic energy balance, chloroplast integrity, carbon flow and epigenetic regulation of isoprenoid biosynthesis during leaf development and senescence - - - EUR 180 277,20 - - - Italy - - - Research Organisations - - The methyl erythritol phosphate (MEP) pathway in the chloroplast synthesizes isoprenoids (a class of hydrocarbons) by almost exclusively utilising carbon and energy supplied by photosynthesis in plant leaves. Volatile - isoprenoids (antioxidant hydrocarbons), isoprenoid-type cytokinins (plant ‘youth’ hormone), carotenoids (photoprotective pigments), and abscisic acid (plant ‘stress’ hormone) are some of the active isoprenoid end-products of the MEP pathway that play - a role in leaf senescence. We aim to quantify and model age-specific relationships between photosynthesis and MEP pathway during natural and abiotic-stress induced leaf senescence in three different plant systems: wheat (a crop), poplar (a plantation - tree) and Arabidopsis (the model species for genomics). By combining leaf age-specific chloroplast energy balance estimation through photosynthesis modelling, quantification of carbon demands of isoprenoid biosynthesis using stable isotope tracing - and advanced real-time analytical techniques, monitoring plastome and chloroplast integrity, and whole-epigenome sequencing, LEAF-OF-LIFE will (i) develop a versatile quantitative method for predicting leaf senescence trajectories based on the - relationship between photosynthesis and isoprenoid biosynthesis during senescence and (ii) identify novel gene cascades involved in epigenomic regulation of the MEP pathway during natural and abiotic stress-induced leaf senescence. A thorough - understanding of leaf age-specific changes in energy and carbon demands of isoprenoid biosynthesis will provide a strong mechanistic basis to phenology models of autumn senescence in deciduous trees. Discovery of novel gene regulatory cascades - involved in age-specific changes in isoprenoid biosynthesis will be spearheading new research intended to target MEP pathway so as to alter leaf life span (delay stress-induced leaf senescence) in major global crops and plantations. - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - LEAF-OF-LIFE - - - H2020-MSCA-IF-2016 - - - 746821 - - - - - KATHOLIEKE UNIVERSITEIT LEUVEN - - - EUR 160 800 - - - Coping with Inhospitable Sweetness: Insights from a (Diversity)^3 Study of Nectar Acinetobacters - - - EUR 160 800 - - - Belgium - - - Higher or Secondary Education Establishments - - "Plants are hotspots of microbial diversity, and novel lineages of plant-associated microorganisms are continuously described. Recently, floral nectar has been identified as the natural habitat of different highly adapted - yeasts and bacteria which can withstand elevated sugar contents and the presence of plant secondary metabolites with defensive functions. As a consequence of their metabolism, these microorganisms can reduce the nutritional value of nectar and - profoundly alter its chemistry, and thus modify pollinators’ foraging behavior and indirectly affect plant fitness. Although the bacterial species Acinetobacter nectaris and A. boissieri (""nectar acinetobacters"", NAs) are among the most frequent - bacterial nectar-dwellers, their diversity and intriguing ubiquitous occurrence in floral nectar still remain poorly characterized. Through a comprehensive study of the phenotypic, phylogenetic and genomic diversity (“diversity(D)^3 approach”) of - NAs, the proposed project aims to explain why A. nectaris and A. boissieri are particularly well suited to thrive in the “inhospitable sweetness” of floral nectar. This research question will be addressed by using state-of-the-art methodologies of - high-throughput phenotyping, phylogenetic inference and whole-genome sequencing and analysis. The combination of expertises in applied phylogenetics of the applicant (experienced researcher, ER) and in phenomics and genomics of the host institute - will be key for a successful completion of the work plan. Additionally, the implementation of this action will involve training in management, communication, dissemination and exploitation of results, and networking, all of which will boost the ER's - potential for reaching a position of professional maturity." - - 2019-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Belgium - - - D3NAs - - - H2020-MSCA-IF-2016 - - - 742964 - - - - - KOBENHAVNS UNIVERSITET - - - EUR 200 194,80 - - - Monotonicity in Logic and Complexity - - - EUR 200 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - MiLC will develop logical characterisations of monotone complexity classes, yielding languages and systems which are machine-independent and well suited for reasoning over such classes of functions. Monotone Boolean functions - abound in the theory of computation, e.g. in sorting algorithms and clique detection in graphs, and nonuniform classes of monotone functions have been well studied in computational complexity under the lens of monotone circuits. - - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - MiLC - - - H2020-MSCA-IF-2016 - - - 753431 - - - - - THE FRANCIS CRICK INSTITUTE LIMITED - - - EUR 183 454,80 - - - Role of perforin-like proteins and phospholipases in malaria parasite egress - - - EUR 183 454,80 - - - United Kingdom - - - Research Organisations - - The malaria parasite Plasmodium falciparum, which causes ~600,000 deaths annually, propagates within host erythrocytes. Roughly synchronous egress of blood stage parasites in vivo causes the periodic fevers associated with - malaria and is essential for parasite replication. Blocking parasite egress can stop disease progression, so understanding its mechanism is key to identifying new drug targets. Egress of malaria parasites from host erythrocytes involves the rupture - of two membranes- the parasitophorous vacuole membrane and the erythrocyte membrane. It is unclear how the parasitophorous vacuole membrane ruptures during egress, and what mechanism is responsible for poration of the erythrocyte membrane. While it - has been shown that egress is protease-dependent, the effector molecules that bring about the disruption of both membranes remain unknown. Potential effector molecules include parasite perforin-like proteins (PLPs) and phospholipases. This project - aims to test the hypothesis that Plasmodium PLPs and phospholipases are involved in malarial egress. First, we will apply newly developed conditional knockout strategies to establish the role in egress of a candidate perforin-like protein. Second, we - aim to devise a novel conditional genetic screen to identify egress related phospholipases in a medium-throughput manner. This work will add to the efforts being made to understand egress and will attempt to develop a much needed forward genetic - screen in the malaria parasite. The interdisciplinary approach proposed here combines the experienced researcher (ER)’s skills in genomics and the host laboratory’s expertise in malarial cell biology and conditional knockout technologies. This will - equip the ER with the right exposure and new skills to pursue a future independent research career in malaria research. - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - MalariaEgress - - - H2020-MSCA-IF-2016 - - - 751865 - - - - - KAROLINSKA INSTITUTET - - - EUR 185 857,20 - - - Molecular Mechanisms of Dynamic and Spatial Control of Eph Receptors clustering - - - EUR 185 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - There is mounting evidence that the spatial and temporal organization of ligands at cell-cell interfaces modulates signaling. In particular, for Eph receptors and their ligands (ephrins) this phenomenon is widely recognized - but poorly understood due to difficulties in controlling and analyzing membrane protein microenvironments at the nanoscale. A combination of different techniques ranging from DNA nanotechnology to high resolution microscopies via standard biochemical - techniques and computational tools will be used to provide a molecular understanding of the roles of the spatial and temporal organization of ligands in receptor signaling. Substrates that recreate the intramembrane signalling geometry at cell-cell - contacts are designed and produced by employing ligand decorated DNA nanostructures anchored on artificial supported lipid bilayers. This allows an unparalleled control of spatial distribution of the ligands and their dynamics. TIRF/STORM - super-resolution microscopy is used to measure size and dynamics of clustering and biochemical assays will quantify the receptor spatial distribution and activation levels. Together with computational simulation and modeling of clustering dynamics, - these efforts will lead to a molecular mechanism of spatial organization of ligands and receptors during clustering and how this affects signaling. - - 2018-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - DynaSpaCER - - - H2020-MSCA-IF-2015 - - - 707203 - - - - - CARDIFF UNIVERSITY - - - EUR 195 454,80 - - - Artificial engineered Phonons for application in Integrated Photonics - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Stimulated Brillouin (SBS) and Raman Scattering (SRS) effects have led to numerous applications in fiber optics (e.g. tunable laser and amplifiers). In integrated photonics, recent progress in opto-mechanics have shown that - artificial analogue to the Raman effect, namely mechanical structure resonances, can be engineered and could results in new applications. That said, a few challenges must still be addressed before fiber applications of SRS can be transposed in a µm - size optical chip. In particular the frequency of the mechanical resonances -aka artificial phonons- is still too low (<10Ghz) for most applications, and the light-phonon interaction is much weaker in waveguides compared to what is obtained in - cavity opto-mechanics. Moreover current approaches relying on Radio-frequency measurements do not allow investigating high frequency (>10GHz) resonances. - - - 2019-09-05, Grant Agreement terminated - - - 2017-09-06 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - APIP - - - H2020-MSCA-IF-2016 - - - 751939 - - - - - EUROPEAN SOUTHERN OBSERVATORY - ESO EUROPEAN ORGANISATION FOR ASTRONOMICAL RESEARCH IN THE SOUTHERN HEMISPHERE - EUROPEAN SOUTHERN OBSERVATORY - ESO EUROPEAN ORGANISATION FOR ASTRONOMICAL RESEARCH IN THE SOUTHERN HEMISPHERE - - - EUR 1 999 250 - - - Globular clusters as living fossils of the past of galaxies - - - EUR 1 999 250 - - - Germany - Germany - - - Research Organisations - Research Organisations - - Globular clusters (GCs) are enigmatic objects that hide a wealth of information. They are the living fossils of the history of their native galaxies and the record keepers of the violent events that made them change their - domicile. This proposal aims to mine GCs as living fossils of galaxy evolution to address fundamental questions in astrophysics: (1) Do satellite galaxies merge as predicted by the hierarchical build-up of galaxies? (2) Which are the seeds of - supermassive black holes in the centres of galaxies? (3) How did star formation originate in the earliest phases of galaxy formation? To answer these questions, novel population-dependent dynamical modelling techniques are required, whose development - the PI has led over the past years. This uniquely positions him to take full advantage of the emerging wealth of chemical and kinematical data on GCs. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - ArcheoDyn - - - ERC-2016-COG - - - 724857 - - - - - KAROLINSKA INSTITUTET - - - EUR 185 857,20 - - - An innovative class of nanoparticles (“SmartCubes”) for the targeted delivery of protein therapeutics - - - EUR 185 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - 'SmartCubes' are an innovative class of nanoparticles for the targeted delivery of protein therapeutics. The objective is to deliver high levels of membrane proteins to cancer cells to combat disease. I will achieve this by - creating novel 'sponge-like' targeted nanoparticles (SmartCubes) to selectively deliver unprecedented levels of a cancer therapeutic protein to colon adenocarcinoma cells. - - 2018-05-31, ongoing project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - SmartCubes - - - H2020-MSCA-IF-2015 - - - 703666 - - - - - GLAXOSMITHKLINE VACCINES SRL - INSTITUTO DE MEDICINA MOLECULAR - UNIVERSITA DEGLI STUDI DI MILANO - UNIVERSITEIT LEIDEN - ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOCIENCIAS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - THE UNIVERSITY OF MANCHESTER - SVEUCILISTE U RIJECI, MEDICINSKI FAKULTET - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - GLYCOUNIVERSE GMBH & CO KGAA - - - EUR 3 554 499,69 - - - A training network for the rational design of the next generation of well-defined glycoconjugate vaccines - - - EUR 3 554 499,69 - - - Italy - Portugal - Italy - Netherlands - Spain - France - United Kingdom - Croatia - Germany - Germany - Germany - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - GLYCOVAX is a network for the education of promising young scientists who will learn how to rationally design a next generation of well-defined and innovative glycoconjugate vaccines to improve current preventive therapies and - to tackle unmet medical needs. Glycoconjugate vaccines represent the key for success of vaccination in children. The covalent linkage to proteins renders carbohydrates able to evoke a T-cell memory response. Current vaccines are prepared from - heterogeneous mixtures of sugars linked by unspecific methods to the carrier protein giving complex mixtures of products. Due to this intricate structure, it has not been possible to apply a medicinal chemistry approach in the development of - glycoconjugate vaccines and to fully understand their mechanism of action. Combination of novel approaches for glycan synthesis and site-selective conjugation methods now gives access to conjugates defined in sugar component and attachment site, thus - leading to robust structure-immunogenicity relationship. Advancements in structural biophysics can be applied to select the optimal glycan antigen. By combining the beneficiaries’ expertise in carbohydrate synthesis, bioconjugation, high throughput - screening, structural glycobiology, vaccinology and immunology, together with the experience in project management, GLYCOVAX will create a multidisciplinary environment where 14 young researchers will contribute to develop a novel route towards - improved, safer and better characterized glycoconjugate vaccines, and contemporarily acquire transferable skills which will lead them to become the new leaders of academic or industrial research. The network will involve 9 academic groups and 2 - industrial partners as Beneficiaries, and one SME as Partner Organization. The profound interaction between academy and industry will aid the students to get new concepts and visions for translating their ideas from the bench to the manufacturing of - the next generation of glycoconjugate vaccines. - - 2019-10-31, ongoing project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Italy - - - GLYCOVAX - - - H2020-MSCA-ITN-2015 - - - 675671 - - - - - THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN - STICHTING VU - VRIJE UNIVERSITEIT BRUSSEL - UNIVERSITETET I BERGEN - ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOMATERIALES- CIC biomaGUNE - WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER - IMANOVA LIMITED - ASTRAZENECA AB - STICHTING VUMC - - - EUR 3 912 634,77 - - - PET Imaging in Drug Design and Development - - - EUR 3 912 634,77 - - - United Kingdom - Netherlands - Belgium - Norway - Spain - Germany - United Kingdom - Sweden - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - The drug development strategy currently pursued by the pharmaceutical industry worldwide is inefficient and unsustainable for the health care system. To keep the latter affordable, drug development should become more efficient - and drug treatment should become more “personalized” and “rationalized”. Molecular imaging can play a pivotal role in changing the landscape of drug design/development and improving the health care system. Positron Emission Tomography (PET) imaging, - in particular, is the technology that has the potential to lead this fundamental innovation by providing at a much earlier stage reliable answers to key questions emerging during the care cycle: what and where is the disease? Is the disease - accurately targeted by the therapy? Is the treatment effective? By answering the questions above, PET imaging has the capacity to render much more effectively the transition from pre-clinical to clinical phase, and to strongly facilitate the - development of better drugs at an earlier stage and in a much more sustainable manner. The main obstacle to this change of paradigm in drug design and development is the lack of suitably trained translational scientists directly involved in PET - imaging and imaging scientists with high-profile training in chemistry and PET-radiochemistry, which is particularly dramatic in Europe. This consortium is ideally suited to fill this gap, by providing top-quality training to the next generation of - translational PET imaging scientists who will play a key role in shaping the future of drug design and development. The PET3D ETN will focus on 15 cutting-edge research projects in the 3 main therapeutic areas (oncology, cardiovascular, central - nervous system) that will be conducted by 15 ESRs at 8 European beneficiary Institutions, 6 academic (all having a PET center on site) and 2 non-academic (one with a PET center on site and one big pharmaceutical company) representing the drug design - and development terminus of the project. - - 2020-05-31, ongoing project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - PET3D - - - H2020-MSCA-ITN-2015 - - - 675417 - - - - - DIGITAL RESEARCH INFRASTRUCTURE FOR THE ARTS AND HUMANITIES - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW - GEORG-AUGUST-UNIVERSITAT GOTTINGENSTIFTUNG OFFENTLICHEN RECHTS - - - EUR 1 930 139 - - - Humanities at Scale: Evolving the DARIAH-ERIC - - - EUR 1 941 576,25 - - - France - France - Netherlands - Germany - - - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - - The ‘Humanities at Scale’ project will further the DARIAH ERIC’s aim to integrate digitally enabled research in the arts and humanities in Europe and beyond and to operate a platform to enable trans-national arts and - humanities research. The project will help DARIAH sustain existing knowledge in digital arts and humanities in Europe and enable new one. DARIAH connects various hubs of excellence in the domain and helps them share their results and innovations. By - sharing knowledge, DARIAH works proactively to enhance the reach of digital arts and humanities within the European Research Area (ERA). This proposals aims to address some critical limitations of the current model of sharing knowledge in DARIAH and - of connecting the national services in digital arts and humanities initiatives in Europe. - - 2017-12-31, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-3-2015 - Individual implementation and operation of ESFRI projects - - - RIA - Research and Innovation action - - - France - - - HaS-DARIAH - - - H2020-INFRADEV-1-2015-1 - - - 675570 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSITY OF GLASGOW - THE UNIVERSITY OF MANCHESTER - MEDIZINISCHE HOCHSCHULE HANNOVER - UNIVERSITAETSKLINIKUM HEIDELBERG - OULUN YLIOPISTO - MOSAIQUES DIAGNOSTICS GMBH - ACQUIFER AG - - - EUR 3 137 377,32 - - - Development and disease of the renal tract - - - EUR 3 137 377,32 - - - France - United Kingdom - United Kingdom - Germany - Germany - Finland - Germany - Germany - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The renal tract (kidneys, the ureters, bladder) is a complex organ system crucial for maintaining the body homeostasis. This organ system arises from different precursor pools through a complex program of patterning, - differentiation and morphogenesis in embryonic development. Alteration of this program leads to renal tract malformations (RTM) that are incompatible with a healthy life. While some of these RTM can be surgically corrected, others develop into - chronic entities that may lead to renal failure; the burden for the patients and for the socio-economic impact for the health systems is immense. Although congenital RTM are amongst the most frequent human birth defects, the different programs that - direct normal and pathological development have remained poorly understood. - - - 2019-05-31, ongoing project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - France - - - RENALTRACT - - - H2020-MSCA-ITN-2014 - - - 642937 - - - - - KUNGLIGA TEKNISKA HOEGSKOLAN - UNIVERSITEIT UTRECHT - FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA) - FORSCHUNGSZENTRUM JULICH GMBH - THE UNIVERSITY OF EDINBURGH - THE UNIVERSITY OF MANCHESTER - EUROPEAN MOLECULAR BIOLOGY LABORATORY - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - FORWARD TECHNOLOGIES AB - BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION - IAN HARROW CONSULTING LTD - - - EUR 4 782 286 - - - Centre of Excellence for Biomolecular Research - - - EUR 4 782 286,25 - - - Sweden - Netherlands - Spain - Germany - United Kingdom - United Kingdom - Germany - Germany - Sweden - Spain - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Life Science research has become increasingly digital, and this development is accelerating rapidly. Biomolecular modelling techniques such as homology modelling, docking, and molecular simulation have advanced tremendously - due to world-leading European research, resulting in extreme demands for better computational performance and throughput as these tools are used in applied research and industrial development. This research has direct influence on our daily life in - areas such as health and medical applications, the development of new drugs, efficient drug delivery, biotechnology, environment, agriculture and food industry. Life Science is one of the largest and fastest growing communities in need of high-end - computing, and it is a critically important industrial sector for Europe. However, compared to some other disciplines, the use of e-Infrastructure is still relatively new - many advanced techniques are not applied commercially due to limited - experience. It requires significant support to: - - 2018-10-31, ongoing project | - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.3."> - - - EINFRA-5-2015 - Centres of Excellence for computing applications - - - RIA - Research and Innovation action - - - Sweden - - - BioExcel - - - H2020-EINFRA-2015-1 - - - 675728 - - - - - THE UNIVERSITY OF MANCHESTER - DEIMOS CASTILLA LA MANCHA SL - GOMSPACE APS - UNIVERSITAET STUTTGART - UNIVERSITAT POLITECNICA DE CATALUNYA - UNIVERSITY COLLEGE LONDON - THE TECH TOYBOX, INC. - EUROCONSULT SA - Concentris Research Management GmbH - - - EUR 5 726 750 - - - DISCOVERER – DISruptive teChnOlogies for VERy low Earth oRbit platforms - - - EUR 5 726 750 - - - United Kingdom - Spain - Denmark - Germany - Spain - United Kingdom - United States - France - Germany - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - We envision a radical redesign of Earth observation platforms for sustained operation at significantly lower altitudes than the current state of the art, using a combination of new aerodynamic materials, aerodynamic control - and air-breathing electric propulsion for drag-compensation, for a variety of observation methods with the aim of creating a new platform paradigm. - - 2021-03-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-01-2016-2017 - FET-Open research and innovation actions - - - RIA - Research and Innovation action - - - United Kingdom - - - DISCOVERER - - - H2020-FETOPEN-1-2016-2017 - - - 737183 - - - - - BILKENT UNIVERSITESI VAKIF - - - EUR 157 845,60 - - - “The Role of Urbanization in Female Empowerment: the Turkish Case in Comparative Perspective” - - - EUR 157 845,60 - - - Turkey - - - Higher or Secondary Education Establishments - - Female empowerment is perceived both as a policy tool for the betterment of overall welfare of the societies, as well as a policy target both in Europe and throughout the world. However, women still lag behind men in - education, economic affluence, and political representation in many countries, even in some of the most “developed” ones. The proposed project aims to shed light on the dynamics behind female empowerment, specifically focusing on the role of - urbanization. Modernization and industrialization bring about several advantages for many women such as better education and livelihoods, better say for themselves and their children, and fairer political representation. Yet, urbanization remains - insufficient to eradicate the extant problems that women have faced and creates new challenges and obstacles for many. The proposed project argues that female empowerment is a multi-faceted, multi-level phenomenon that calls for such a research - strategy and hypothesizes that urbanization has a complex, non-linear effect on female empowerment. To better understand the concept at hand and pinpoint the ways to enhance it, the project incorporates country-, local-, and individual-levels of - analysis. The project also combines the strengths of quantitative and qualitative techniques to offer a fuller picture about female empowerment. The main focus of the project is the relationship between urbanization and female empowerment in Turkey, - while it also provides a comparative global-level analysis with clear implications for Europe. The proposed research aims to make novel contributions to the feminist studies, urban studies, development studies, and democratization literatures and - enhance the competitiveness of European research. In addition to its academic merit, the project also has policy implications aimed at policymakers for future policies and projects, as well as the society at large which could be implemented - throughout Europe. - - 2018-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Turkey - - - Female Empowerment - - - H2020-MSCA-IF-2015 - - - 702073 - - - - - BILKENT UNIVERSITESI VAKIF - - - EUR 145 845,60 - - - Energy Efficient FPGA Accelerators for Graph Analytics Applications - - - EUR 145 845,60 - - - Turkey - - - Higher or Secondary Education Establishments - - It is reported that data centers today consume up to 3 percent of the global electricity usage. This is expected to increase in the upcoming years as the amount of data processed in the cloud increases substantially. An - effective way for data centers to achieve better performance and energy efficiency is to perform computation on specialized processing elements. Field programmable gate arrays (FPGAs) enable customization of logic after manufacturing to achieve - better energy efficiency compared to general purpose processors. Today, prominent hardware and software companies are investing in data center solutions that integrate FPGAs with CPUs, and significant energy consumption and performance improvements - have been demonstrated for several data center applications. However, the main barrier for wide spread adoption of FGPAs in data centers is the cost of programming, which typically requires months of development time by hardware designers. This makes - it unaffordable for small-to-medium software companies to effectively utilize the available FPGAs. The purpose of this project is to lower this barrier for emerging graph analytics applications for knowledge discovery and machine learning. The basic - idea is to use an abstract interface that allows a domain expert to describe an application as a set of serial functions defined per vertex and/or edge. We propose a customizable implementation template that automatically maps the abstract user - functions to massively parallel FPGA implementations. The proposed template will hide from users many low level implementation details such as parallelization, pipelining, synchronization, memory access optimization, race and deadlock avoidance, etc. - This will help bridge the gap between high level application descriptions and costly hardware implementations. Our preliminary architecture simulations have shown that the proposed graph processors can achieve significantly better energy efficiency - than general purpose processors. - - 2018-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Turkey - - - FPGA Accelerators - - - H2020-MSCA-IF-2015 - - - 704476 - - - - - THE UNIVERSITY OF NOTTINGHAM - - - EUR 195 454,80 - - - Simulations for multi-level Analysis of interactions in Tunnelling based on the Building Information Modelling technology - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - With increasing urbanization and mobility, the need for underground facilities and consequently efficient and safe design and construction techniques grows. The goal of the SATBIM project is to develop a multi-level simulation - model for tunnel-structure interaction integrated in the framework of Building Information Modelling to support engineering decisions during the project life cycle and to allow for the evaluation and minimization of risks on the existing - infrastructure. SATBIM is an integrated platform for structural analysis, visualisation and optimization of the mechanized tunnelling process from early stages of the design over to the construction and the operation phase. The complete concept will - be validated using industrial data with reference to the Rastatter tunnel project in Germany. The output will have wide implication on technology with expected high academic and industrial impact. - - 2018-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SATBIM - - - H2020-MSCA-IF-2015 - - - 702874 - - - - - THE UNIVERSITY OF MANCHESTER - THE UNIVERSITY OF MANCHESTER - LANCASTER UNIVERSITY - - - EUR 1 456 252,50 - - - New Science and Technology of Artificial Layered Structures and Devices - - - EUR 1 456 252,50 - - - United Kingdom - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The extensive and growing library of layered crystals opens up the exciting possibility of exfoliating them into single atomic layers and stacking these atomic layers back together in new sequences to fabricate a new class of - artificial van der Waals solids, with novel properties and functionalities. The principal objectives of this proposal are to study the fundamental physics and chemistry of novel materials, structures and devices synthesised by assembling different - two-dimensional (2D) crystals and to exploit their unique properties for diverse applications. - - - 2021-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - MATTERDESIGN - - - ERC-2015-STG - - - 679689 - - - - - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH - - - EUR 1 463 750 - - - Multi Ion Reflection Apparatus for Collinear Laser Spectroscopy of radionuclides - - - EUR 1 463 750 - - - Switzerland - Switzerland - - - Research Organisations - Research Organisations - - Employing laser spectroscopy (LS) to study radionuclides is equally rich in its long tradition as it is manifold in its active pursuit today as virtually all radioactive ion beam (RIB) facilities do or are planning to host - dedicated setups. Probing the hyperfine structure of an atom or ion with laser light is a powerful technique to infer nuclear properties such as a nuclide’s spin, charge radius, or electromagnetic moments. This information provides insight into a - wide range of contemporary questions in nuclear physics such as the mechanism driving the emergence and disappearance of nuclear shells far away from stability. - - 2021-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Switzerland - - - MIRACLS - - - ERC-2015-STG - - - 679038 - - - - - BILKENT UNIVERSITESI VAKIF - BILKENT UNIVERSITESI VAKIF - - - EUR 1 995 625 - - - Graphene based smart surfaces: from visible to microwave - - - EUR 1 995 625 - - - Turkey - Turkey - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The aim of this proposal is to develop adaptive camouflage systems using graphene-enabled smart surfaces. We propose a new class of active surfaces capable of real-time electrical-control of its appearance in a very broad - spectrum ranging from visible to microwave covering 6 orders of magnitude in wavelength. The proposed method relies on controlling electromagnetic waves by tuning density of high-mobility charges on single or multilayers of atomically thin graphene - electrodes. We will realize this goal by efficient gating of large-area graphene using ionic liquids which yields unprecedented ability to control intensity and phase of the reflected and transmitted electromagnetic waves from the surface. Based on - underlying physical mechanisms and applications, the proposed research plan is structured in 3 main directions; (1) Active surfaces in microwave and THz, (2) Active thermal surfaces, and (3) Active surfaces in the visible. - - - 2021-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Turkey - - - SmartGraphene - - - ERC-2015-CoG - - - 682723 - - - - - MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN - MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN - - - EUR 1 999 877 - - - Neural mechanisms of multisensory perceptual binding - - - EUR 1 999 877 - - - Germany - Germany - - - Research Organisations - Research Organisations - - Sensory perception involves the discrimination and binding of multiple modalities of sensory input. This is especially evident in the somatosensory system where different modalities of sensory input, including thermal and - mechanosensory, are combined to generate a unified percept. The neural mechanisms of multisensory binding are unknown, in part because sensory perception is typically studied within a single modality in a single brain region. I propose a multi-level - approach to investigate thermo-tactile processing in the mouse forepaw system from the primary sensory afferent neurons to thalamo-cortical circuits and behaviour. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - ACoolTouch - - - ERC-2015-CoG - - - 682422 - - - - - THE UNIVERSITY OF LIVERPOOL - AMSTERDAM SCIENTIFIC INSTRUMENTS BV - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH - FONDAZIONE CENTRO NAZIONALE DI ADROTERAPIA ONCOLOGICA - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - GSI HELMHOLTZZENTRUM FUER SCHWERIONENFORSCHUNG Gmbh - ION BEAM APPLICATIONS SA - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - EBG (Entwicklungs- und Betriebsgesellschaft) MedAustron GmbH - PAUL SCHERRER INSTITUT - UNIVERSITY COLLEGE LONDON - THE UNIVERSITY OF MANCHESTER - UNIVERSIDAD DE SEVILLA - VIALUX MESSTECHNIK + BILDVERARBEITUNG GMBH - - - EUR 3 871 703,52 - - - Optimization of Medical Accelerators - - - EUR 3 871 703,52 - - - United Kingdom - Netherlands - Switzerland - Italy - Spain - Germany - Belgium - Germany - Austria - Switzerland - United Kingdom - United Kingdom - Spain - Germany - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Cancer is a major social problem, and it is the main cause of death between the ages 45-65 years. In the treatment of cancer, radio therapy (RT) plays an essential role. RT with hadrons (protons and light ions), due to their - unique physical and radiobiological properties, offers several advantages over photons for specific cancer types. In particular, they penetrate the patient with minimal diffusion, they deposit maximum energy at the end of their range, and they can be - shaped as narrow focused and scanned pencil beams of variable penetration depth. Although significant progress has been made in the use of particle beams for cancer treatment, an extensive research and development program is still needed to maximize - the healthcare benefits from these therapies. - - - 2020-01-31, ongoing project - - - 2016-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - OMA - - - H2020-MSCA-ITN-2015 - - - 675265 - - - - - BILKENT UNIVERSITESI VAKIF - - - EUR 145 845,60 - - - 3D Silicon Micromachining with Infrared ultrafast LasErs - - - EUR 145 845,60 - - - Turkey - - - Higher or Secondary Education Establishments - - The aim of the present proposal is to initiate an interdisciplinary research program to develop 3D micromachining of silicon towards novel silicon photonics and microfluidic applications. We are motivated by the myriad of - applications based on 3D micromachining of glass that peaked in the early 2000's, and still continues to impact integrated photonics and microfluidics, among other fields. These successes were achieved using lasers at wavelengths for which glass is - transparent (most commonly 1 um, 800 nm and their second harmonics). Most of the important results demonstrated in glass can be carried over to silicon using a long-wavelength laser (beyond 1.1 um, silicon is highly transparent), though it is clear - that the physics will be different, not least because glass is amorphous and silicon is crystalline. To this end, we propose an interdisciplinary research effort that includes first developing the necessary laser technology, then building up the - physical understanding, and finally pursuing high impact applications. Our approach can be summarized as: - - 2017-09-29, closed project - - - 2015-09-30 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Turkey - - - SMILE - - - H2020-MSCA-IF-2014 - - - 660769 - - - - - TECHNISCHE UNIVERSITEIT EINDHOVEN - UNIVERSITEIT UTRECHT - STOCKHOLMS UNIVERSITET - LEIBNIZ-INSTITUT FUER NEUE MATERIALIEN GEMEINNUETZIGE GMBH - THE UNIVERSITY OF MANCHESTER - CHALMERS TEKNISKA HOEGSKOLA AB - AKZO NOBEL PULP AND PERFORMANCE CHEMICALS AB - SEPAREX SAS - NANOLYTICS GMBH - - - EUR 3 378 227,90 - - - A multiscale approach towards mesostructured porous material design - - - EUR 3 378 227,90 - - - Netherlands - Netherlands - Sweden - Germany - United Kingdom - Sweden - Sweden - France - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - MULTIMAT addresses (1) the industrial and societal need for affordable materials that have a highly defined and large porosity together with the required (mechanical, chemical and/or thermal) robustness for application in - thermal insulation, catalysts, fuel cells and oil spill remediation and (2) the scientific need to better understand the mechanisms underlying the assembly of small building blocks into larger structures that are ordered hierarchally across multiple - scales ("multiscale assembly"). Together this will contribute to achieving MULTIMAT's future aim: Understanding and ultimately steering the bottom-up construction of materials with complex hierarchical structures. - - - 2020-02-29, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Netherlands - - - MULTIMAT - - - H2020-MSCA-ITN-2015 - - - 676045 - - - - - MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN - MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN - - - EUR 1 457 938 - - - Safeguarding Cell Identities: Mechanisms Counteracting Cell Fate Reprogramming - - - EUR 1 457 938 - - - Germany - Germany - - - Research Organisations - Research Organisations - - Regenerating tissues by reprogramming cells has the potential to become a therapeutic approach for replacing lost tissues in patients suffering from injury or degenerative diseases such as Alzheimer’s or Muscular Dystrophy. - Strategies to generate required tissues using embryonic stem cells or induced pluripotent stem cells (iPSCs) are associated with either ethical or medical safety issues. An alternative strategy is to directly reprogram cells to the required tissue - type by forced expression of cell fate-inducing transcription factors (TFs). Direct reprogramming (DR) has the potential to circumvent unsafe proliferative pluripotent cell stages and it allows in vivo procedures. However to date, DR is successful in - only a few cell types and it is not well understood why most cells are refractory to DR. Recently, we provided evidence that inhibitory mechanisms play an important role in restricting cell fate conversion. We identified factors inhibiting direct - conversion of germ cells into specific neurons or muscle cells. Additionally, preliminary studies in our group revealed other factors that inhibit ectopic cell fate induction in somatic cells. - - - 2020-02-29, ongoing project - - - 2015-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - REPROWORM - - - ERC-2014-STG - - - 637530 - - - - - DANMARKS TEKNISKE UNIVERSITET - THE UNIVERSITY OF MANCHESTER - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - LUNDS UNIVERSITET - NOVOZYMES A/S - WYATT TECHNOLOGY EUROPE GMBH - MEDIMMUNE LIMITED - KOBENHAVNS UNIVERSITET - - - EUR 4 067 745,48 - - - Protein-excipient Interactions and Protein-Protein Interactions in formulation - - - EUR 4 067 745,48 - - - Denmark - United Kingdom - Germany - Sweden - Denmark - Germany - United Kingdom - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - The revolution of biotechnology has led to the creation of various types of therapeutic biologics with the potential to provide treatment for new chronic and malignant diseases. Though the potential advantages of biologics lay - in their high specificity and potency combined with few side effects, their formulation still remains a large challenge to pharmaceutical scientists. This is in part due to the complex, not-well understood relationship between the physicochemical - properties of proteins and formulation conditions required for protein stability. A comprehensive understanding of the molecular mechanisms behind protein stabilization and solubility would provide the formulation scientists with knowledge of the - interplay between formulation and stability that in turn could potentially make formulation development faster, cheaper and less labour intensive than the currently used broad screening approach. Understanding the susceptibilities of formulations to - protein aggregation and denaturation can reduce the response time to for instance product failure. Few universities in Europe have formulation of biologics as a scientific subject. Consequently, the pharmaceutical industry is forced to train - scientists - a challenge for larger companies, and an insurmountable task for smaller companies. Scientists in the field of structural biology, biophysics, protein formulation and stability have formed a consortium to systematically map - physicochemical properties of biologics, formulation conditions and protein stability. The main objective of the consortium is to provide a new generation of innovative and entrepreneurial early-stage researchers that will develop methodologies, - tools and databases to guide the formulation of robust biologics. The consortium will not only provide an excellent platform to train a new generation of formulation scientists, but also establish avenues for designing new formulation strategies and - thereby securing the leading edge of EU expertise. - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Denmark - - - PIPPI - - - H2020-MSCA-ITN-2015 - - - 675074 - - - - - UNIVERSITY OF BATH - UNIVERSITY OF BATH - MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN - THE UNIVERSITY OF EDINBURGH - - - EUR 2 497 996 - - - Evolutionary genomics: new perspectives and novel medical applications - - - EUR 2 497 996 - - - United Kingdom - United Kingdom - Germany - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - - To make for better diagnostics and safer applications of genomics we need a better understanding of our genome and how it functions. Until recently we thought we knew: intergenic sequence must be largely “junk” and mutations - that, for example, affect genes but not the protein (synonymous mutations) must be effectively neutral. This degenerate genome view accords with the nearly-neutral theory’s prediction that selection will be weaker when populations are small. But is - this all there is to it? I shall investigate two new interrelated perspectives on genome evolution. First, I suggest that to mitigate errors, owing to our high error rates, our genome can be under stronger, not weaker, selection. Second, that errors - might be a source of evolutionary novelty. Error mitigation, my team has shown, often involves selection on seemingly innocuous mutations such as synonymous changes. Remarkably, we discovered that selection to ensure error-proof splicing is possibly - more prevalent on synonymous mutations when populations are small, making seemingly innocuous mutations stronger candidates for human diseases. I shall provide the first test of the new error-proofing perspective through comparative genomic analysis - on synonymous site evolution. To investigate error as a source of novelty I shall consider whether expression piggy-backing (expression of a gene affecting its neighbors) forces rewiring of gene networks. Importantly, I shall translate our new - understanding to enable better diagnostics and improved therapeutics. I shall develop a much-needed computer package to identify candidate disease-causing synonymous changes. In addition, knowing how synonymous sites modulate splicing will allow me - to design better intronless transgenes. Transgenes must also be inserted in genomic regions immune to piggy-backing. I will examine transposable element related piggy-backing to characterize “safe” sites for therapeutic gene insertion and mammalian - transgenesis more generally. - - 2020-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - EvoGenMed - - - ERC-2014-ADG - - - 669207 - - - - - CENTRO DE NEUROCIENCIAS E BIOLOGIACELULAR ASSOCIACAO - FYZIOLOGICKY USTAV AKADEMIE VED CESKE REPUBLIKY VEREJNA VYZKUMNA INSTITUCE (VVI) - UNIVERSITA DEGLI STUDI DI BARI ALDO MORO - Faculdade de Farmácia da Universidade de Lisboa - INSTYTUT BIOLOGII DOSWIADCZALNEJ IM. M. NENCKIEGO POLSKIEJ AKADEMII NAUK - UNIVERSIDADE DO PORTO - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - CONSIGLIO NAZIONALE DELLE RICERCHE - HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 3 202 195,68 - - - Bioenergetic Remodeling in the Pathophysiology and Treatment of Non-Alcoholic Fatty Liver Disease - - - EUR 3 202 195,68 - - - Portugal - Czech Republic - Italy - Portugal - Poland - Portugal - France - Italy - Germany - Spain - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Research Organisations - - FOIE GRAS provides innovative training for 13 early stage researchers (ESRs) to answer two critical and unanswered questions: a) Is hepatic bioenergetic remodelling involved in NAFLD pathogenesis, and target for stratification - or therapeutic/lifestyle interventions? and b) Is the disruption of the gut-liver axis involved in NAFLD progression? In Western Societies, there has been a recent surge of non-alcoholic fatty liver disease (NAFLD). Its progression to nonalcoholic - steatohepatitis (NASH) is a leading risk factor for development of Type 2 diabetes, cirrhosis, and hepatocellular carcinoma. FOIE GRAS is first in supporting a cohesive and synergistic intersection of complementary and interdisciplinary training - skills from academic and non-academic partners. FOIE GRAS combines strong scientific expertise with integrated and complementary training in translational research, clinical practice, technology commercialization, and public outreach, the combination - of which in targeting NAFLD is lacking in the EU. Industrial partners CETICS, Mediagnost and Seahorse Biosciences provide experience on technology commercialization alongside scientific contributions while the affiliated patient organization will - contribute with important training in societal awareness topics. ESRs training will utilize network-wide workshops and secondments to foster translation of basic research to clinical applications and SME creation. This diverse yet integrated skill - set enhances the employment prospects of the trained researchers in both academic and non-academic sectors. Researchers will be endowed with excellent basic scientific knowledge and timely technology transfer know-how for developing novel therapeutic - approaches for reversing the burden of NAFLD, thereby advancing both health and economic well-being of European citizens and approaching NAFLD research in the EU from its counterparts in the US and Asia. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Portugal - - - Foie Gras - - - H2020-MSCA-ITN-2016 - - - 722619 - - - - - TELECOMMUNICATION SYSTEMS INSTITUTE - THE QUEEN'S UNIVERSITY OF BELFAST - STMICROELECTRONICS GRENOBLE 2 SAS - ACCIONA CONSTRUCCION SA - THE UNIVERSITY OF MANCHESTER - POLITECNICO DI TORINO - CHALMERS TEKNISKA HOEGSKOLA AB - SYNELIXIS LYSEIS PLIROFORIKIS AUTOMATISMOU & TILEPIKOINONION MONOPROSOPI EPE - - - EUR 4 237 397,50 - - - Energy-efficient Heterogeneous COmputing at exaSCALE - - - EUR 4 237 397,50 - - - Greece - United Kingdom - France - Spain - United Kingdom - Italy - Sweden - Greece - - - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - In order to reach exascale performance current HPC servers need to be improved. Simple scaling is not a feasible solution due to the increasing utility costs and power consumption limitations. Apart from improvements in - implementation technology, what is needed is to refine the HPC application development as well as the architecture of the future HPC systems. - - 2018-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.2."> - - - FETHPC-1-2014 - HPC Core Technologies, Programming Environments and Algorithms for Extreme Parallelism and Extreme Data Applications - - - RIA - Research and Innovation action - - - Greece - - - ECOSCALE - - - H2020-FETHPC-2014 - - - 671632 - - - - - MEDIZINISCHE UNIVERSITAET WIEN - CARDIFF UNIVERSITY - FUNDACIO SANT JOAN DE DEU - KOBENHAVNS UNIVERSITET - THE UNIVERSITY OF LIVERPOOL - THE UNIVERSITY OF MANCHESTER - UNIVERSITA DEGLI STUDI DI FIRENZE - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - UNIVERSITE DE PICARDIE JULES VERNE - STICHTING VU - BIOTALENTUM TUDASFEJLESZTO KFT - S.A.F.AN. BIOINFORMATICS - SAS DI PUGLIESE LUISA - TISSUEGNOSTICS GMBH - - - EUR 3 657 194,64 - - - Calcium-Sensing Receptor (CaSR): Therapeutics for Non-Communicable Diseases - - - EUR 3 657 194,64 - - - Austria - United Kingdom - Spain - Denmark - United Kingdom - United Kingdom - Italy - United Kingdom - France - Netherlands - Hungary - Italy - Austria - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The calcium sensing receptor (CaSR) is a class C Gprotein-coupled receptor that plays a pivotal role in systemic calcium metabolism by regulating parathyroid hormone secretion and urinary Ca excretion. Abnormal CaSR function - is implicated in calciotropic disorders, and in non-calciotropic disorders such as Alzheimer’s disease (AD), cardiovascular disease (CVD), diabetes (DM), sarcopenia and cancer, which account for >25% of the global disease burden. The CaSR is a - unique GPCR whose principal physiological ligand is the Ca2+ ion; it is expressed almost ubiquitously; interacts with multiple Gα subtypes regulating highly divergent downstream signalling pathways, depending on the cellular context. The CaSR - Biomedicine is a fully translational project that utilises the concept of a single molecule, the CaSR, influencing a range of physiological and disease processes, to develop a unique, strong multidisciplinary and intersectoral scientific training - programme preparing 14 young scientists to become specialists in GPCR biology and signalling. - - 2020-02-29, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Austria - - - CaSR Biomedicine - - - H2020-MSCA-ITN-2015 - - - 675228 - - - - - TTY-SAATIO - AARHUS UNIVERSITET - UNIVERSITAT ZURICH - THE UNIVERSITY OF MANCHESTER - INSTITUT JOZEF STEFAN - ALLIANCEBERNSTEIN LIMITED - ING GROEP NV - - - EUR 3 463 286,40 - - - Training for Big Data in Financial Research and Risk Management - - - EUR 3 463 286,40 - - - Finland - Denmark - Switzerland - United Kingdom - Slovenia - United Kingdom - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - BigDataFinance, a Marie Skłodowska-Curie Innovative Training Network “Training for Big Data in Financial Research and Risk Management”, provides doctoral training in sophisticated data-driven risk management and research at - the crossroads of Finance and Big Data for 13 researchers. The main objectives are i) to meet an increasing commercial demand for well-trained researchers experienced in both Big Data techniques and Finance and ii) to develop and implement new - quantitative and econometric methods for empirical finance and risk management with large and complex datasets. To achieve the objectives, the emphasis is put on exploiting big data techniques to manage and use datasets that are too large and complex - to process with conventional methods. - - 2019-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Finland - - - BigDataFinance - - - H2020-MSCA-ITN-2015 - - - 675044 - - - - - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - ECOLE NORMALE SUPERIEURE - - - EUR 185 076 - - - Optical strategies to investigate NMDA receptor functional diversity and its therapeutic potential - - - EUR 185 076 - - - France - France - - - Research Organisations - Higher or Secondary Education Establishments - - NMDA receptors (NMDARs) form a class of receptors gated by glutamate, the major neurotransmitter in the mammalian brain. These receptors play fundamental roles in synaptic transmission and plasticity. They are also involved in - numerous pathologies including stroke, mental retardation or schizophrenia. NMDARs are thus targets of strong therapeutic interest. NMDARs are tetramers usually composed of two GluN1 and two GluN2 subunits encoded by four different genes (GluN2A-D), - resulting in a large number of receptor subtypes having distinct anatomical, biophysical, pharmacological and signalling properties. Understanding the functional role of these individual subtypes in the brain is of great importance to develop new - strategies to counteract the deleterious effects of NMDAR dysregulation. However, tools allowing targeting of a specific population of NMDARs in a given neuronal circuit are currently lacking. The OptoNMDA research programme proposes the development - of an innovative optical approach to selectively enhance the activity of NMDARs containing the GluN2B subunit (GluN2B-NMDARs) in ex vivo and in vivo preparations. This approach consists in developing photo-convertible polyamine derivatives that can - reversibly isomerize between an inactive and active configuration with light to act on the GluN2B-NMDAR polyamine allosteric modulating site in a precise spatio-temporal manner (opto-allostery). I will study the physiological and potential - therapeutic roles of these compounds by testing their effects on synaptic transmission and plasticity and on genetic models of NMDAR hypo-function. Compared to previous studies targeting orthosteric (competitive) sites, the opto-allostery approach - will allow manipulation of NMDARs in a more specific and physiological manner. This project should thus provide critical novel information on NMDARs, and more generally, on the physiology and pathology of excitatory synapses. - - 2018-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - France - - - OptoNMDA - - - H2020-MSCA-IF-2015 - - - 701467 - - - - - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH - THE UNIVERSITY OF MANCHESTER - JOHANNES GUTENBERG-UNIVERSITAT MAINZ - Advanced Accelerator Applications - INSTITUTO SUPERIOR TECNICO - FONDAZIONE CENTRO NAZIONALE DI ADROTERAPIA ONCOLOGICA - KATHOLIEKE UNIVERSITEIT LEUVEN - LEMER PAX - - - EUR 2 829 269,88 - - - MEDICIS-produced radioisotope beams for medicine - - - EUR 2 829 269,88 - - - Switzerland - United Kingdom - Germany - France - Portugal - Italy - Belgium - France - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Pure accelerated radioisotope beams have been used for 50 years in fundamental physics R&D, e.g. for nuclear structure studies (pear shaped exotic nuclei, Nature 2013); CERN-ISOLDE plays a central role in developing - accelerator technologies and fostering collaborative approaches to advance this field of isotope mass separation online. Our most recent contribution was the use of nanomaterial targets for more intense and reliable beam production, and laser ion - sources for their purification (discovery of yet unknown 233Francium). - - 2019-03-31, ongoing project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Switzerland - - - MEDICIS-PROMED - - - H2020-MSCA-ITN-2014 - - - 642889 - - - - - MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN - MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN - - - EUR 1 993 421 - - - DNA end protection in Immunity and Cancer - - - EUR 1 993 421 - - - Germany - Germany - - - Research Organisations - Research Organisations - - This proposal addresses a fundamental issue in molecular biology: how is repair of DNA double-strand breaks (DSBs) steered towards the appropriate physiological outcome? DSBs are cytotoxic DNA lesions that arise as a - by-product of DNA replication, but also as a physiological intermediate during antigen receptor diversification in the Immune system. DNA end processing is a major determinant of DSB repair outcome. Resection of DNA ends is a prerequisite for - physiological repair of replication-associated breaks by homologous recombination, but detrimental for productive end-joining events during immunoglobulin class switch recombination (CSR) in B lymphocytes. Furthermore, inappropriate resection of DSBs - can cause loss of genetic information and chromosome deletions, which are common features of cancer genomes. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - DNAendProtection - - - ERC-2014-STG - - - 638897 - - - - - BILKENT UNIVERSITESI VAKIF - - - EUR 157 845,60 - - - Control of Triboelectricity from Micro to Macro as a Principle ofSticking, Particulate Contamination and ESD Prevention of Micromachines - - - EUR 157 845,60 - - - Turkey - - - Higher or Secondary Education Establishments - - Microelectromechanical systems (MEMS) is the technology of micromachines up to 100 micrometers in size. In the era of minituarization, MEMS represents a huge and rapidly growing market, which will exceed $20B by 2020 and - Europa constitutes about 20% of the total world market. However, the technology struggles with some problems preventing its fast development. This proposal aims to deal with those related to tribocharging (frictional electricity), which has been - overlooked so far. Tribocharging is a very common event causing value losses due to electrostatic sticking and electrostatic discharging (ESD) problems in many industrial manufacturing processes such as static cling of powder materials in drug - processing, ESD problems in electronics. Attempts to eliminate static electricity from solid and liquid materials includes the addition of antistatic agents to them that increases the deposition of water from ambient moisture and the addition or - doping of some conducting materials e.g. carbon powder into plastics and a conductive path removes the excess electrostatic charge. However, these solutions are not generally very practical and limited by the specific applications in micro - dimensions. In this proposal, we focused on the elimination of static charge that accumulates on MEMS. To eliminate static electricity from MEMS, I will use the chemical approach that we introduced (Science, 2013). Firstly, we aim to eliminate the - excess static charge from polymer based (MEMS) using this approach by incorporating antistatic and anti-sticking properties to these micro devices for the first time. Secondly, ESD will be eliminated in these micro devices using the same approach - based on the scavenging of excess electrostatic charges. Finally, it will be possible to extend the lifetime of these micro devices by eliminating problems such as sticking, (charged) particulate contamination due to e.g. wear, and ESD that mainly - arise from tribocharging. - - 2018-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Turkey - - - Tribocharge - - - H2020-MSCA-IF-2015 - - - 707643 - - - - - POLITECNICO DI TORINO - ECOLE NATIONALE SUPERIEURE DE CHIMIE DE MONTPELLIER - - - EUR 139 500 - - - Synthesis and photopolymerisation of new fluorinated macromonomers for the obtaining of high performance fluoropolymers - - - EUR 238 500 - - - Italy - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The PhotoFluo project consists in a consortium of three teams (two from Europe and one from Canada) committed to work for developing novel fluoropolymers suitable for optical and electronic devices, membranes for fuel cells - and Li batteries, microfluidics, and biomaterials. This ambitious goal will be achieved starting from designing new perfluoropolyalkylether building blocks (PFPAE) improving safety (not bioaccumulative like perfluoroalkylics) and having chemical - inertness, flexibility in a wide temperature range, very low refractive index and wettability. PFPAE will be chain extended to tune final properties; exploiting OH functionalities, these precursors will be functionalized to make telechelic - macromonomers for suitable crosslinking (via both radical and ionic processes). The polymers will be synthesized by photoinduced polymerization, chosen as an efficient and eco-friendly process: the polymer formation is fast (no more than minutes - compared to hours requested by thermal processes), is solvent free, is carried out at room temperature consuming low amount of energy, permits spatial resolution, as it mainly occurs in the illuminated areas. After obtaining an original portfolio of - PFPAE polymers, they will be fully characterized and tested in view of innovate applications. - - - 2020-01-31, ongoing project - - - 2016-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Italy - - - PhotoFluo - - - H2020-MSCA-RISE-2015 - - - 690917 - - - - - UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN - ABERYSTWYTH UNIVERSITY - LOUGHBOROUGH UNIVERSITY - VORNIA LIMITED - MSC.SOFTWARE LTD. - - - EUR 931 500 - - - Novel Cell Migration Assay Based on Microtissue Technology and Tissue-Specific Matrices - - - EUR 1 053 000 - - - Ireland - United Kingdom - United Kingdom - Ireland - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Cell migration assays are commonly used to study wound healing, cancer cell invasion, and tissue development. Problems associated with the gap closure assays typically employed are that: - - - 2019-05-31, ongoing project | - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Ireland - - - MATRIXASSAY - - - H2020-MSCA-RISE-2014 - - - 644175 - - - - - OBSERVATOIRE DE PARIS - - - EUR 185 076 - - - High Sensitivity Matter-Wave Gravitation Sensors - - - EUR 185 076 - - - France - - - Higher or Secondary Education Establishments - - After more than 20 years of fundamental research, atom interferometers have reached sensitivity and - - - 2018-04-14, ongoing project - - - 2016-04-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - MWGRAV - - - H2020-MSCA-IF-2014 - - - 660081 - - - - - MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN - MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN - - - EUR 150 000 - - - Exploring the Potential for Therapeutic Lineage Reprogramming of Diabetes - - - EUR 150 000 - - - Germany - Germany - - - Research Organisations - Research Organisations - - Diabetes is a degenerative disease that affects over 350 million persons worldwide. Type 1 and type 2 diabetes are associated with either destruction or dysfunction of pancreatic insulin-producing β cells. Despite the - availability of insulin as treatment to temporarily restore the glucostasis, this remedy is unable to avoid either the acute dangers of hypoglycemia or the long-term complications of hyperglycemia. Eventually, the challenge of treating diabetes - centers on the replacement of pancreatic β cells. Due to serious organ shortage for pancreas transplantation, cell-based therapy represents the most promising option and different potential sources for new β cells are currently being explored, - including embryonic stem cells and other cell types. A particularly attractive therapeutic strategy is to convert liver adult cells of diabetic patients into functional pancreatic β cells through lineage reprogramming. Fate conversion of liver to - pancreas is conceivable for numerous physiological and developmental reasons, and, possibly, suitable for future clinical applications. My ERC-funded project (ERC Starting Grant “HEPATOPANCREATIC”) is focused on the molecular mechanisms underlying - cellular plasticity between liver and pancreatic cells. This study has led to the identification of a novel factor, whose ectopic expression converts mouse liver cells into pancreatic cells. Here, we propose a defined and focused set of measures - aimed at: 1) extending these findings in human liver cells to assess whether this strategy may be exploited to develop an autologous cell-based therapy of diabetes; and 2) elaborating a solid intellectual property strategy. The “TheLiRep” Proof of - Concept (PoC) funding will ensure the full exploitation of the ERC idea and bridge the gap between my research and the earliest stage of a marketable innovation. - - 2016-10-31, closed project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2014 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Germany - - - TheLiRep - - - ERC-2014-PoC - - - 641036 - - - - - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH - TTY-SAATIO - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - KARLSRUHER INSTITUT FUER TECHNOLOGIE - TECHNISCHE UNIVERSITAT DARMSTADT - ISTITUTO NAZIONALE DI FISICA NUCLEARE - UNIVERSITEIT TWENTE - CONSORCIO PARA LA CONSTRUCCION EQUIPAMIENTO Y EXPLOTACION DEL LABORATORIO DE LUZ SINCROTRON - CENTRO DE INVESTIGACIONES ENERGETICAS, MEDIOAMBIENTALES Y TECNOLOGICAS-CIEMAT - SCIENCE AND TECHNOLOGY FACILITIES COUNCIL - THE UNIVERSITY OF LIVERPOOL - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - INTER-UNIVERSITY RESEARCH INSTITUTE CORPORATION, HIGH ENERGY ACCELERATOR RESEARCH ORGANISATION - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - UNIVERSITE DE GENEVE - - - EUR 2 999 000 - - - European Circular Energy-Frontier Collider Study - - - EUR 3 989 842 - - - Switzerland - Finland - France - France - Germany - Germany - Italy - Netherlands - Spain - Spain - United Kingdom - United Kingdom - United Kingdom - Japan - Switzerland - Switzerland - - - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The award of the 2013 Nobel Prize for Physics acknowledged the leading role of Europe in particle physics, which has a global community of over 10,000 scientists. To reinforce its pole position throughout the 21st century, - Europe must be ready to propose an ambitious post-LHC accelerator project by 2018/19. This is one of the main recommendations of the updated European Strategy for Particle Physics, adopted by the CERN Council in May 2013. - - 2019-05-31, ongoing project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-1-2014 - Design studies - - - RIA - Research and Innovation action - - - Switzerland - - - EuroCirCol - - - H2020-INFRADEV-1-2014-1 - - - 654305 - - - - - TECHNISCHE UNIVERSITEIT DELFT - - - EUR 242 929,80 - - - Biocrete – Bio-inspired bacteria-based stress-responsive concrete. - - - EUR 242 929,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - The proposed project aims to develop biocrete a bio-inspired stress-responsive concrete. Biocrete will be realized through the cross-pollination of the fields of: bacteria-based self-healing concrete; and bio-inspired - organic-inorganic materials synthesis. This cross-pollination will see bacteria incorporated in hydrogel systems for the formation of novel bio-inspired bacteria-activated organic-inorganic composite materials, or bio-composite materials for short. - In order to develop these bio-composite materials technologies the applicant will receive advanced training in organic-inorganic materials synthesis, with a focus on calcium carbonate precipitation in polymer hydrogels. He will also master - state-of-the-art organic-inorganic materials analysis techniques including serial sectioning by cryo-focused ion beam milling (cryo-FIB), and ultimately by cryo-scanning transmission electron microscopy (cryo-STEM). Such techniques will provide - insights on the formation of the bio-composite materials, which will be key in ultimately controlling their morphology and mechanical properties. Biocrete will be born through the incorporation of these bio-composite materials technologies into - concrete materials. Biocrete will be tested for its crack sealing and mechanical performance. It is envisaged biocrete have a superior crack healing action over conventional concrete materials, resulting in better functional performance and more - durable concrete construction. - - 2020-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Netherlands - - - Biocrete - - - H2020-MSCA-IF-2016 - - - 747736 - - - - - INSTITUTE OF COMMUNICATION AND COMPUTER SYSTEMS - THE UNIVERSITY OF MANCHESTER - BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - SCIENCE AND TECHNOLOGY FACILITIES COUNCIL - INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM - ZEROPOINT TECHNOLOGIES AB - ICEOTOPE RESEARCH & DEVELOPMENT LTD - ARM LIMITED - SYNELIXIS LYSEIS PLIROFORIKIS AUTOMATISMOU & TILEPIKOINONION MONOPROSOPI EPE - MAXELER TECHNOLOGIES LIMITED - NEURASMUS BV - ISTITUTO NAZIONALE DI FISICA NUCLEARE - ISTITUTO NAZIONALE DI ASTROFISICA - EUROPEAN CENTRE FOR MEDIUM-RANGE WEATHER FORECASTS - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - - - EUR 19 949 022,50 - - - Co-designed Innovation and System for Resilient Exascale Computing in Europe: From Applications to Silicon - - - EUR 19 949 022,50 - - - Greece - United Kingdom - Spain - Greece - United Kingdom - Belgium - Sweden - United Kingdom - United Kingdom - Greece - United Kingdom - Netherlands - Italy - Italy - United Kingdom - Germany - - - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - - To achieve the demands of extreme scale and the delivery of exascale, we embrace the computing platform as a whole, not just component optimization or fault resilience. EuroEXA brings a holistic foundation from multiple - European HPC projects and partners together with the industrial SME focus of MAX for FPGA data-flow; ICE for infrastructure; ALLIN for HPC tooling and ZPT to collapse the memory bottleneck; to co-design a ground-breaking platform capable of scaling - peak performance to 400 PFLOP in a peak system power envelope of 30MW; over four times the performance at four times the energy efficiency of today’s HPC platforms. Further, we target a PUE parity rating of 1.0 through use of renewables and - immersion-based cooling. - - 2021-02-28, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.2."> - - - FETHPC-01-2016 - Co-design of HPC systems and applications - - - RIA - Research and Innovation action - - - Greece - - - EuroEXA - - - H2020-FETHPC-2016 - - - 754337 - - - - - MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN - - - EUR 159 460,80 - - - Enzymatic DNA deamination and the immunity/cancer balance - - - EUR 159 460,80 - - - Germany - - - Research Organisations - - Genomic instability is a key hallmark of cancer. Chromosome translocations require the formation of pairs of double-strand breaks (DSB) and trans-chromosomal ligation of the broken ends. Members of the AID/APOBEC family of - enzymes deaminate cytosine (C) to uracil (U) in the context of a polynucleotide substrate. Excision of the U residue from DNA produces an abasic site, leading to incision of the DNA strand containing the abasic site by the conventional base-excision - repair pathway. The introduction of proximal incisions on both DNA strands can generate a DSB intermediate for chromosomal translocation. AID acts on C residues at immunoglobulin loci in activated B cells to trigger antibody gene diversification and - is the only member of the AID/APOBEC family that is currently known to act physiologically on endogenous nuclear DNA. Off-target deamination by AID results in nucleotide substitutions and genomic rearrangements in B lymphocyte tumours. APOBEC1 edits - mRNA transcripts in the small intestine. Liver-directed misexpression of APOBEC1 is oncogenic in transgenic mice. APOBEC3 enzymes are ubiquitously expressed and act on C residues in the cDNA viral replication intermediates as part of a host - restriction pathway. APOBEC3A and APOBEC3B have been shown to be capable of causing genomic damage in mammalian cells. Access to the nucleus by APOBEC family members likely permits DNA deamination activity that introduces mutations and genomic - instability during tumourigenesis. I have generated mice that harbour FLAG-tagged forms of AID, APOBEC1, APOBEC3A or APOBEC3B inserted at the ROSA26 locus, preceded by a floxed stop sequence for conditional expression. This system will be used to - understand the role of cytosine deamination in tumour progression in tissue- and time-specific contexts in vivo through whole genome sequencing of tumours. The long-term goal is to initiate the development of reagents to regulate APOBEC activity in - basic science and clinical oncology. - - 2017-03-31, closed project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - APOBEC - - - H2020-MSCA-IF-2014 - - - 660883 - - - - - MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN - - - EUR 171 460,80 - - - The role of danger signal and cellular competition in the elimination of B cells lacking the B cell receptor. - - - EUR 171 460,80 - - - Germany - - - Research Organisations - - B cells represent a specialized population of lymphocytes responsible for adaptive immune responses and life-long immune memory. All mature B cells carry B cell receptors (BCRs) on the surface and it is through the BCR that B - cells recognize foreign antigens and subsequently provide antibody responses. Acute ablation of the BCR in resting mature naïve B cells in mice leads to a fast disappearance of Immunoglobulin negative (Ig-) B cells from peripheral lymphoid system. - This phenomenon has been mainly explained by a “tonic” signal provided by the BCR, essential for B cell survival. However, there are at least two other possible, not mutually exclusive, mechanisms. In this proposal I hypothesize that i) loss of the - BCR structure provides a “danger” signal leading to apoptosis of Ig- B cells; ii) Ig- B cells are eliminated as a result of cellular competition with the Ig+ B cells. I will test these 2 hypothesis by i) addressing the unfolded protein response (UPR) - in Ig- B cells as a possible “danger signal” followed by in vivo genetic rescue experiments testing for its causality in Ig- B cell depletion; ii) I will produce pure Ig- B cell cultures, exploiting the novel system of genome editing of primary B - cells, and address - in vitro and in vivo - the fitness, proliferation and differentiation capacity of Ig- B cells in presence and absence of cellular competition with Ig+ B cells. By addressing these points my work might provide a first-time - evidence for the existence of “a danger signal” initiated in a B cell upon BCR ablation and prove its causality in Ig- B cell disappearance. On the other hand, elimination of Ig- B cells as a result of cellular competition with Ig+ B cells is a novel - concept with important implications for lymphoma biology and potential clinical applications. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - BCRdangerCOMPETITION - - - H2020-MSCA-IF-2016 - - - 752747 - - - - - RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN - - - EUR 159 460,80 - - - Database Analysis for Evaluation of Seismic Performance Assessment Tools - - - EUR 159 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - In highly industrialised regions, earthquakes severely affect societies in terms of economic, social and environmental consequences due to the complex integrated and highly sensitive industries - even in areas of medium to low - seismicity like Europe. Whereas the seismic behaviour of typical building structures is broadly understood and reflected in technical guidelines and damage prognosis tools worldwide, event reports and even assessment tools for industrial facilities - are scarce, mainly because affected facilities are usually not generally accessible and are, thus, not covered by reconnaissance teams. After the 2012 Earthquake in the Italian Regione Emilia-Romagna (RE-R), however, the regional government gathered - very detailed data on seismic damages to more than 3000 industrial / business facilities in order to distribute financial compensations. The data was collected in an extremely comprehensive database including – besides many other aspects – type, size - and location of the business as well as damage to structures, components and stored goods and costs of reconstruction. Within the proposed DatA ESPerT project, the researcher will exploit this globally unique SFINGE-database in a rigorous way, in - order to develop mathematical tools to assess the seismic performance of industrial facilities and to give damage prognoses for future earthquakes. Due to the comparable socio-economic context and similar seismic hazard levels, the research results - will be valid for many regions in Southern Europe. Additional aspects of the project consider the development of cost/performance curves for seismic mitigation measures and the investigation of the geographical damage distribution in relation to the - seismological circumstances in the Emilia-Romagna. The work is strongly supported by RWTH Aachen, by Munich RE reinsurance company and by RE-R who assured to the researcher within an official agreement access to the confidential SFINGE-database in - the project's framework. - - 2019-06-15, ongoing project - - - 2017-06-16 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - DatA ESPerT - - - H2020-MSCA-IF-2016 - - - 743458 - - - - - CONSIGLIO NAZIONALE DELLE RICERCHE - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - LEIBNIZ INSTITUT FUER TROPOSPHAERENFORSCHUNG e.V. - NATIONAL OBSERVATORY OF ATHENS - NORSK INSTITUTT FOR LUFTFORSKNING STIFTELSE - ILMATIETEEN LAITOS - PAUL SCHERRER INSTITUT - HELSINGIN YLIOPISTO - EIDGENOSSISCHE MATERIALPRUFUNGS- UND FORSCHUNGSANSTALT - EUROPEAN CENTRE FOR MEDIUM-RANGE WEATHER FORECASTS - METEOROLOGISK INSTITUTT - NATIONAL INSTITUTE OF RESEARCH AND DEVELOPMENT FOR OPTOELECTRONICS - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - JRC -JOINT RESEARCH CENTRE- EUROPEAN COMMISSION - UNIVERSIDAD DE VALLADOLID - UNIVERSIDAD DE GRANADA - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - KONINKLIJK NEDERLANDS METEOROLOGISCH INSTITUUT-KNMI - CESKY HYDROMETEOROLOGICKY USTAV - LUNDS UNIVERSITET - THE CYPRUS INSTITUTE - RHEINISCHES INSTITUT FUER UMWELT-FORSCHUNG AN DER UNIVERSITAET ZU KOELN E.V. - DEUTSCHER WETTERDIENST - UNIVERSITY OF LEEDS - NATURAL ENVIRONMENT RESEARCH COUNCIL - Pannon Egyetem - B.I. Stepanov Institute of Physics of the National Academy of Sciences of Belarus - CONSORZIO NAZIONALE INTERUNIVERSITARIO PER LE SCIENZE FISICHE DELLA MATERIA - INSTITUTE OF NUCLEAR RESEARCH AND NUCLEAR ENERGY - BULGARIAN ACADEMY OF SCIENCES - NATIONAL UNIVERSITY OF IRELAND GALWAY - Instytut Geofizyki Polskiej Akademii Nauk - - - EUR 9 541 194,51 - - - Aerosols, Clouds, and Trace gases Research InfraStructure - - - EUR 10 126 484,54 - - - Italy - France - Germany - Greece - Norway - Finland - Switzerland - Finland - Switzerland - United Kingdom - Norway - Romania - Germany - Belgium - Spain - Spain - Spain - Netherlands - Czech Republic - Sweden - Cyprus - Germany - Germany - United Kingdom - United Kingdom - Hungary - Belarus - Italy - Bulgaria - Ireland - Poland - - - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Other - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - - ACTRIS-2 addresses the scope of integrating state-of-the-art European ground-based stations for long term observations of aerosols, clouds and short lived gases capitalizing work of FP7-ACTRIS. ACTRIS-2 aims to achieve the - construction of a user-oriented RI, unique in the EU-RI landscape. - - - 2019-04-30, ongoing project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.2."> - - - INFRAIA-1-2014-2015 - Integrating and opening existing national and regional research infrastructures of European interest - - - RIA - Research and Innovation action - - - Italy - - - ACTRIS-2 - - - H2020-INFRAIA-2014-2015 - - - 654109 - - - - - TECHNISCHE UNIVERSITEIT DELFT - - - EUR 177 598,80 - - - Exploring Thermoelectric and Spintronic properties of Molecular Devices - - - EUR 177 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - The development of wearable and diffuse electronics has prompted a global need for converting heat into electrical power. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - TherSpinMol - - - H2020-MSCA-IF-2016 - - - 748642 - - - - - BOURNEMOUTH UNIVERSITY - CENTRE DE RECHERCHE DE L INSTITUT PAUL BOCUSE - HELLENIC HEALTH FOUNDATION - RONGE & PARTNER GMBH - KOBENHAVNS UNIVERSITET - UNIVERSITY OF MACEDONIA - - - EUR 499 500 - - - Shaping Smarter Consumer Behaviour and Food Choice - - - EUR 499 500 - - - United Kingdom - France - Greece - Austria - Denmark - Greece - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Compared to meals prepared at home, meals eaten out tend to contain more calories, total fat and saturated fat and it is here where the consumer has very little control or knowledge of the nutrient profile of the food they are - eating (Bohm and Quartuccio, 2008). The positive association between the rise in consumption of food prepared outside the home and the increasing prevalence of obesity has been described as a major health and wellbeing societal challenge. Attempts to - increase public awareness of appropriate ways to eat more healthily unfortunately do not seem to have led to significant changes in patterns of food purchase and consumption especially from an eating ‘out-of-home’ situation. It has become obvious - that the development of effective measures for improvement requires further systematic research and a radical approach. The aim of FoodSMART is to develop an innovative technical (ICT) menu solution that enables informed consumer choice when eating - out that takes into account individual characteristics (such as culture, dietary requirements and age group) as well as product (specification) and environmental cues (choice architecture and consumption setting). - - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - United Kingdom - - - FoodSMART - - - H2020-MSCA-RISE-2014 - - - 643999 - - - - - UNIVERSITA DEGLI STUDI DI VERONA - - - EUR 164 203,80 - - - Medicine, Heresy and Freedom of Thought in sixteenth-century Italy:a Network of Dissident Physicians in the Confessional Age - - - EUR 164 203,80 - - - Italy - - - Higher or Secondary Education Establishments - - I am an expert researcher on the religious and medical history of sixteenth-century Italy. Applying for a GF, supervised by professors Findlen - at Stanford - and Barbierato - at the Univr-, I will examine and interpret the - link between sixteenth-century heretical thought and the rise of modern science, exploring the local, national and trans-national levels of this connection. NETDIS will use digital humanities tools to reveal the network of Italian physicians who - developed non-conformist religious views. By exploring the nature, extent and function of the ties among physicians, NETDIS will inquire into the genesis of freedom of thought - which stands today at the core of European identity - as an embryonic - value shared by most physicians in response to the spread of intolerance in the confessional age. This will have a positive insights for several ongoing difficulties facing the EU, such as the revival of religious violence (i.e. terrorism). Working - on NETDIS I will learn innovative methodologies; I will gain new perspectives for an international career; I will write my first monograph. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Italy - - - netdis - - - H2020-MSCA-IF-2016 - - - 748645 - - - - - THE UNIVERSITY OF BIRMINGHAM - - - EUR 269 857,80 - - - Stem Cell-Derived Exosomes for the treatment of Traumatic and Degenerative Eye Disease - - - EUR 269 857,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The death and dysfunction of retinal ganglion cells (RGC) is a major cause of blindness in traumatic and degenerative ocular disease. For example, 60M people are affected by glaucoma with 4.5M becoming blind in both eyes, - whilst optic neuritis affects 5/100,000 people and represents a significant problem for sufferers. RGC are the sole projection neurons and their axons make up the optic nerve, making them exquisitely sensitive to injury. As CNS neurons are - irreplaceable, neuroprotective strategies are paramount to therapies aimed at preserving vision but as of yet, no such therapy exists. Current research has demonstrated significant neuroprotection by mesenchymal stem cells (MSC) including those from - the bone marrow (BMSC), acting not as replacements for RGC but rather, as paracrine-mediated support cells. Clinical trials are already ongoing to test their efficacy in patients. Despite this, the exact mechanism behind their neuroprotective - potential is not well understood. Recent studies have shown that exosomes, extracellular vesicles containing proteins, mRNA and miRNA may mediate much of the paracrine support offered by MSC and thus act as an easily purifiable cell-free alternative - therapy for RGC neuroprotection. This proposal aims to assess the therapeutic efficacy of BMSC-derived exosomes, their characterisation and that of their RNA cargo. We will test these exosomes in animal models of traumatic (optic nerve crush) and - degenerative (glaucoma) eye disease. Specifically, this proposal employs a novel strategy to promote RGC survival (relevant to ONC and glaucoma) and axon regeneration (relevant to optic nerve crush) through the use of exosomal delivery of mRNA/miRNA - into injured RGC utilizing in vitro and in vivo injury models, RNAseq and CRISPR technology. - - 2020-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - EXO-EYE - - - H2020-MSCA-IF-2016 - - - 749346 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 146 591,10 - - - Temporal delays in mathematical models of cell biology processes - - - EUR 146 591,10 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The primary aim of the action is the construction and analysis of new predictive and verifiable mathematical models that can uncover the effects of time delays upon various cell biology processes. In this timely project we aim - to apply cutting edge functional differential equation techniques to interrogate a number of cell biology processes of huge current interest, including collective cell movement, tumour growth and self-organizing pattern formation. The ultimate goal - of this research is to develop new mathematical ways to understand and control cell biology processes. The successful outcome of this project will be robust and experimentally testable mathematical theories that can be applied to a wide variety of - biological and medical problems, whenever temporal delays are relevant. - - 2019-01-09, ongoing project - - - 2017-07-10 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - TEMPOMATH - - - H2020-MSCA-IF-2016 - - - 748193 - - - - - MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN - - - EUR 171 460,80 - - - Identification and validation of human proteins that control tau seeding in cell-based and in vivo models - - - EUR 171 460,80 - - - Germany - - - Research Organisations - - The microtubule-associated protein tau is the most commonly misfolded protein in neurodegenerative disorders including Alzheimer’s disease and other related tauopathies. These neurological illnesses are hypothesized to share a - common mechanism of disease progression, where pathogenic aggregates or ‘seeds’ of the tau protein function as templates promoting misfolding of functional, soluble tau protein. Under this premise, therapeutic strategies that modulate the seeding - cascade, have high potential to interfere with the disease process. - - - 2019-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - Tau Seeding - - - H2020-MSCA-IF-2016 - - - 752901 - - - - - MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN - - - EUR 171 460,80 - - - In-toto imaging of C. elegans larval development using adaptive optics light-sheet microscopy - - - EUR 171 460,80 - - - Germany - - - Research Organisations - - Our project aims to combine concepts and methodologies from biology, physics and engineering to address a fundamental question in neuroscience: how is the nervous system rewired during development transitions. The nematode C. - elegans is one of the most important model organisms in neuroscience due to its relatively simple stereotypical anatomy, well-studied genetics and behavior, translucent body and nervous system, ideally suited for in-toto (in its entirety) imaging. - Yet most of the knowledge available refers to adult animals, and little is known about neuronal plasticity and mechanisms of behavioral changes during development. - - - 2019-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - Lightsheetelegans - - - H2020-MSCA-IF-2016 - - - 746497 - - - - - THE UNIVERSITY OF BIRMINGHAM - THE UNIVERSITY OF BIRMINGHAM - - - EUR 1 952 373,99 - - - Creating an Alternative umma: Clerical Authority and Religio-political Mobilisation in Transnational Shii Islam - - - EUR 1 952 373,99 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This interdisciplinary project investigates the transformation of Shii Islam in the Middle East and Europe since the 1950s. The project examines the formation of modern Shii communal identities and the role Shii clerical - authorities and their transnational networks have played in their religio-political mobilisation. The volatile situation post-Arab Spring, the rise of militant movements such as ISIS and the sectarianisation of geopolitical conflicts in the Middle - East have intensified efforts to forge distinct Shii communal identities and to conceive Shii Muslims as part of an alternative umma (Islamic community). The project focusses on Iran, Iraq and significant but unexplored diasporic links to Syria, - Kuwait and Britain. In response to the rise of modern nation-states in the Middle East, Shii clerical authorities resorted to a wide range of activities: (a) articulating intellectual responses to the ideologies underpinning modern Middle Eastern - nation-states, (b) forming political parties and other platforms of socio-political activism and (c) using various forms of cultural production by systematising and promoting Shii ritual practices and utilising visual art, poetry and new media. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - ALTERUMMA - - - ERC-2016-COG - - - 724557 - - - - - MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN - MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN - - - EUR 2 043 804,98 - - - Thermal Magnetic Resonance: A New Instrument to Define the Role of Temperature in Biological Systems and Disease for Diagnosis and Therapy - - - EUR 2 043 804,98 - - - Germany - Germany - - - Research Organisations - Research Organisations - - Temperature is a physical parameter with diverse biological implications and crucial clinical relevance. With an ever increasing interest in thermal applications, non-invasive in vivo methods to modulate temperature and - characterize subsequent effects are imperative. Magnetic resonance (MR) is a mainstay of diagnosis but lacks inherent means for focal thermal modulation. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - ThermalMR - - - ERC-2016-ADG - - - 743077 - - - - - MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN - MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN - - - EUR 1 499 883 - - - Quantitative analysis of variability and robustness in spatial pattern formation - - - EUR 1 499 883 - - - Germany - Germany - - - Research Organisations - Research Organisations - - During embryonic development a single cell turns into a complex organism. This process is characterized by an antagonism between variation and stability. On the one hand, development is a tightly controlled process; tissues - need to be specified at the right time, at the correct spatial position, and with a defined size. On the other hand, regulation should not be too rigid, since embryos need to adjust to environmental perturbations and correct errors caused by noisy - gene expression. We will study variation and stability during pattern formation in the zebrafish heart. We seek to understand the origin of embryo-to-embryo variability as well as robustness against perturbation. - - 2021-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - SPACEVAR - - - ERC-2016-STG - - - 715361 - - - - - MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN - - - EUR 171 460,80 - - - Unlocking the potential of ultrahigh field 23Na magnetic resonance to quantify tissue sodium content for probing viability of the heart: where physics, biology and medicine meet - - - EUR 171 460,80 - - - Germany - - - Research Organisations - - Cardiovascular diseases (CVD) are the leading cause of death with 60% of CVDs associated with coronary artery diseases (CAD). CAD is the major cause of myocardial infarction (MI), commonly known as heart attack, which can be - life threatening and places a huge socio-economic burden on the EU. The most widely used therapy for CAD is revascularization, and myocardial viability is a determining factor and predictor for patient outcomes. Magnetic resonance imaging (MRI) has - become a mainstay of clinical diagnosis, but so far has seen limited use in the study of the heart. Here I aim to unlock the potential of myocardial viability imaging with physiometabolic MRI to provide a new instrument for the diagnosis and - assessment of therapy success of CAD. Therefore I propose a quantitative approach based on MRI of sodium (23Na) that will allow me to observe new features of the working heart, at a level of resolution that will be highly valuable in understanding, - finely diagnosing, and designing treatments for CVD. To meet this goal I pursue the development of cutting edge sodium MRI technology. Its capacity for quantitative assessment of sodium tissue content will be validated in model systems and in healthy - subjects. The clinical applicability of 23Na MRI for viability imaging will be examined in revascularized MI patients. For this purpose I will leverage the sensitivity gain inherent to ultrahigh field MRI (B0≥7.0 T), capitalize on my outstanding - expertise in the field of physiometabolic MRI and build on my interdisciplinary skills formed around MRI physics. In this project, this expertise will be taken to the next level to elucidate the progression of sodium concentration in ischemic - myocardial tissue. This research will eliminate the main barriers to the study of tissue viability and will open entirely new possibilities for non-invasive, in vivo phenotyping as a tool for individualised medicine tailored to offset a major - socio-economic burden on the EU induced by CVD. - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - SODIUMMRI-4-EU - - - H2020-MSCA-IF-2016 - - - 752489 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - BERGISCHE UNIVERSITAET WUPPERTAL - KARLSRUHER INSTITUT FUER TECHNOLOGIE - FORSCHUNGSZENTRUM JULICH GMBH - PAUL SCHERRER INSTITUT - FUNDACION CENTRO DE ESTUDIOS AMBIENTALES DEL MEDITERRANEO - LEIBNIZ INSTITUT FUER TROPOSPHAERENFORSCHUNG e.V. - UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK - ITA-SUOMEN YLIOPISTO - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - ISTITUTO NAZIONALE DI FISICA NUCLEARE - UNIVERSITATEA ALEXANDRU IOAN CUZA DIN IASI - UNIVERSITY OF LEEDS - HELSINGIN YLIOPISTO - - - EUR 8 941 289,64 - - - Integration of European Simulation Chambers for Investigating Atmospheric Processes – Towards 2020 and beyond - - - EUR 9 289 955,24 - - - France - Germany - Germany - Germany - Switzerland - Spain - Germany - Ireland - Finland - Greece - Italy - Romania - United Kingdom - Finland - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Atmospheric simulation chambers are the most advanced tools for elucidating processes that occur in the atmosphere. They lay the foundations for air quality and climate models and also aid interpretation of field measurements. - EUROCHAMP-2020 will further integrate the most advanced European atmospheric simulation chambers into a world-class infrastructure for research and innovation. A co-ordinated set of networking activities will deliver improved chamber operability - across the infrastructure, as well as standard protocols for data generation and analysis. Outreach and training activities will foster a strong culture of cooperation with all stakeholders and users. Collaborative links will be established with - other environmental research infrastructures to promote integration and sustainability within the European Research Area. Cooperation with private sector companies will be actively promoted to exploit the innovation potential of the infrastructure by - supporting development of scientific instruments, sensor technologies and de-polluting materials. Trans-national access will be extended to sixteen different chambers and four calibration centres. A new, upgraded data centre will provide virtual - access to a huge database of experimental chamber data and advanced analytical resources. Joint research activities will enhance the capability of the infrastructure to provide improved services for users. Measurement techniques and experimental - protocols will be further developed to facilitate new investigations on climate change drivers, impacts of air quality on health and cultural heritage, while also stimulating trans-disciplinary research. Advanced process models will be developed for - interpretation of chamber experiments and wider use in atmospheric modelling. Overall, EUROCHAMP-2020 will significantly enhance the capacity for exploring atmospheric processes and ensure that Europe retains its place as the world-leader in - atmospheric simulation chamber research. - - 2020-11-30, ongoing project - - - 2016-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.2."> - - - INFRAIA-01-2016-2017 - Integrating Activities for Advanced Communities - - - RIA - Research and Innovation action - - - France - - - EUROCHAMP-2020 - - - H2020-INFRAIA-2016-1 - - - 730997 - - - - - MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN - MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN - - - EUR 1 500 000 - - - Glioblastoma Subtype Avatar models for Target Discovery and Biology - - - EUR 1 500 000 - - - Germany - Germany - - - Research Organisations - Research Organisations - - The Glioblastoma Multiforme (GBM) is the most common primary brain tumor and it is incurable. Two major challenges affect GBM clinical management: its heterogeneity (which treatment will best fit this very patient?) and its - resistance to available treatments (will the patient benefit in any way from the chosen therapy?). Here we approach these questions with a personalized entry point. First, we aim to create “humanized” experimental models of GBM accurately reflecting - patients at molecular level. These GBM Subtype Avatars models (GSA) will be exploited as “targeted patients” in personalized biology and intervention studies. Since GBM exists as molecular subtypes with similar histopathology but mutually exclusive - genetic lesions and molecular features, we will generate GSA by targeting mutations recurrently associated with Proneural, Classical or Mesenchymal GBM subtypes into adult human neural stem cells (NSC). Evidence supports that these cells can give - rise to high-grade gliomas when engineered with the appropriate genetic lesions. Next, engineered NSC will be orthotopically implanted into immunocompromised rats and the resulting tumors profiled for gene expression, DNA methylation and copy number - aberrations. These profiles will be compared to those generated in patient-derived xenografts and biopsies. Second, to identify drug targets favoring patients’ response to the current standard of care, we will exploit GSA for state-of-art genetic - screens in vivo. Specifically, we will seek for synthetic lethal interactions between DNA damaging agents and the GSA transcriptome using an in vivo CRISPRi screening approach. Third, to investigate the molecular basis of GBM heterogeneity in GSA - models, we will combine genetic and immunophenotypic tracing with gene expression and epigenomic profiling. Identifying tumor-specific vulnerabilities in a dismal disease urging for effective therapies and its molecular fingerprinting convey - conceivably rapid Translation in Oncology. - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - iGBMavatars - - - ERC-2016-STG - - - 714922 - - - - - IBM RESEARCH GMBH - IBM RESEARCH GMBH - - - EUR 150 000 - - - Local molecular profiling of tumor tissue sections: towards personalized immunotherapy - - - EUR 150 000 - - - Switzerland - Switzerland - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Cancer heterogeneity has reinforced the need for personalized treatment modalities. Pre-therapeutic diagnostic testing of heterogeneous tumors helps avoid inefficacious treatments, optimizes targeted therapy and improves - quality of life. Within targeted therapy, immunotherapy has led to significant improvements in treatment outcomes and is swiftly being integrated in diagnostic workflows. In this context, routine diagnostic tests currently do not exist, and - treatments are further challenged by heterogeneity. Spatially resolved molecular probing of tumors prior to treatment would allow prediction of patient response to immunotherapeutics. - - 2018-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Switzerland - - - BioProbe-PIT - - - ERC-2016-PoC - - - 727761 - - - - - MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN - MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN - - - EUR 149 948 - - - SMALL MOLECULES TO TREAT METABOLIC SYNDROME - - - EUR 149 948 - - - Germany - Germany - - - Research Organisations - Research Organisations - - SMALL MOLECULES TO TREAT METABOLIC SYNDROME - - 2018-06-30, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Germany - - - PREVMETSYN - - - ERC-2016-PoC - - - 727726 - - - - - THE UNIVERSITY OF MANCHESTER - UNIVERSITY OF DURHAM - UNIVERSITY OF GLASGOW - GEORG-AUGUST-UNIVERSITAT GOTTINGENSTIFTUNG OFFENTLICHEN RECHTS - KARLSRUHER INSTITUT FUER TECHNOLOGIE - UNIVERSITE CATHOLIQUE DE LOUVAIN - LUNDS UNIVERSITET - UNIVERSITY COLLEGE LONDON - - - EUR 3 930 753,09 - - - Innovative Network for Monte Carlo Event Generators for LHC Physics - - - EUR 3 930 753,09 - - - United Kingdom - United Kingdom - United Kingdom - Germany - Germany - Belgium - Sweden - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - We propose a European Training Network that will provide a total of 540 ESR-months of training in Monte Carlo event generator physics and techniques, and related applications in experimental particle physics. - - 2021-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - MCnetITN3 - - - H2020-MSCA-ITN-2016 - - - 722104 - - - - - MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN - JUSTUS-LIEBIG-UNIVERSITAET GIESSEN - UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA - FUNDACIO CENTRE DE REGULACIO GENOMICA - THE HEBREW UNIVERSITY OF JERUSALEM - AARHUS UNIVERSITET - UNIVERSITAIR MEDISCH CENTRUM UTRECHT - QIAGEN AARHUS AS - - - EUR 3 870 807,84 - - - circular RNA Biology Training Network: from biogenesis to biomarkers - - - EUR 3 870 807,84 - - - Germany - Germany - Italy - Spain - Israel - Denmark - Netherlands - Denmark - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - CircRTrain focuses on circular RNAs (circRNAs), a new large class of single-stranded RNAs with covalently closed ends. CircRNAs have only very recently attracted high general interest and become the focus of an increasing - number of publications: recent discoveries through sequencing technology and computational analyses have revealed the widespread existence of circRNAs in animal cells. Particularly in neural tissues, circRNA expression is high, dynamic, and - evolutionarily conserved. In aging animal brains the expression of certain circRNAs is strongly elevated, suggesting connections to age-related diseases. The study of circRNAs thus emerges as a novel topic with highest importance for the - understanding of such diverse conditions as neurodegenerative diseases, aging, and cancer. Moreover, the highly stable expression and their presence in human blood and exosomes make circRNAs attractive biomarker candidates. - - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - circRTrain - - - H2020-MSCA-ITN-2016 - - - 721890 - - - - - KATHOLIEKE UNIVERSITEIT LEUVEN - KATHOLIEKE UNIVERSITEIT LEUVEN - UNIVERSITAET BERN - - - EUR 1 044 000 - - - Homo Mimeticus: Theory and Criticism - - - EUR 1 044 000 - - - Belgium - Belgium - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Mimesis is one of the most influential concepts in Western thought. Originally invoked to define humans as the “most imitative” creatures in classical antiquity, mimesis (imitation) has recently been at the centre of - theoretical debates in the humanities, social sciences, and the neurosciences concerning the role of “mimicry,” “identification,” “contagion,” and “mirror neurons” in the formation of subjectivity. And yet, despite the growing confirmations that - imitation is constitutive of human behaviour, mimesis still tends to be confined to the sphere of realistic representation. The HOM project combines approaches that are usually split in different areas of disciplinary specialization to provide a - correction to this tendency. - - 2021-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Belgium - - - HOM - - - ERC-2016-STG - - - 716181 - - - - - UNIVERSITY OF STRATHCLYDE - OTTO-VON-GUERICKE-UNIVERSITAET MAGDEBURG - UNIVERSITE DE ROUEN NORMANDIE - STICHTING KATHOLIEKE UNIVERSITEIT - Eidgenössische Technische Hochschule Zürich - THE UNIVERSITY OF MANCHESTER - FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG - Syncom - - - EUR 3 926 004,12 - - - Continuous Resolution and Deracemization of Chiral Compounds by Crystallization - - - EUR 3 926 004,12 - - - United Kingdom - Germany - France - Netherlands - Switzerland - United Kingdom - Germany - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Industries are in need of highly skilled academically trained experts and powerful sets of tools enabling the design, control & prediction of optimized & efficient production process of future high-value products such - as chiral pharmaceuticals. The CORE Network will in parallel train 15 ESRs and develop tools, approaches and methods within the area of Continuous Resolution (CORE), the process to obtain enantiopure molecules of chiral compounds. - - 2020-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - CORE - - - H2020-MSCA-ITN-2016 - - - 722456 - - - - - UNIVERSITAET GRAZ - SOUTH-WEST UNIVERSITY NEOFIT RILSKI - DIETHNES PANEPISTIMIO ELLADOS - Institute of National History Skopje - BILKENT UNIVERSITESI VAKIF - UNIVERSITATEA DE STAT DIN MOLDOVA - INSTITUTUL DE ISTORIE NICOLAE IORGA - ODESSA NATIONAL I.I. MECHNIKOV UNIVERSITY - SHOTA RUSTAVELI STATE UNIVERSITY - FEDERAL STATE BUDGETARY EDUCATIONALINSTITUTION OF HIGHER EDUCATION PYATIGORSK STATE UNIVERSITY - """Matenadaran"" M.Mashtots Institute of Ancient Manuscripts" - AZERBAYCAN MILLI ELMLER AKADEMIYASININ ARXEOLOGIYA VE ETNOGRAFIYA INSTITUTU - - - EUR 1 665 000 - - - Knowledge Exchange and Academic Cultures in the Humanities: Europe and the Black Sea Region, late 18th – 21st Centuries - - - EUR 1 665 000 - - - Austria - Bulgaria - Greece - Former Yugoslav Republic of Macedonia - Turkey - Moldova - Romania - Ukraine - Georgia - Russia - Armenia - Azerbaijan - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - - When the transfer of modern sciences to and the study of the Black Sea Region (BSR) began in the late 18. century, this area was not yet considered part of Europe. The proposed inter/multidisciplinary research and exchange - project’s title refers to that fact. Knowledge and science exchange between Europe and the BSR intensified in the course of the 19th and early 20th century and was interrupted when as result of WWI/WWII a significant part of the BSR was integrated - into the Soviet Union’s orbit. The BSR disappeared behind the Iron Curtain and the academic cultures of West and East drifted apart. The previous 25 years have witnessed strengthening ties between BSR countries and between the BSR and the rest of - Europe as well as globalisation of knowledge and scientific exchange. The integration of the BSR into the European Research Area (ERA) is on the way but not yet completed. The proposed project provides excellent opportunities to critically reflect - the sketched processes and to look into future. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Austria - - - KEAC-BSR - - - H2020-MSCA-RISE-2016 - - - 734645 - - - - - THE UNIVERSITY OF MANCHESTER - - - EUR 183 454,80 - - - Here be Spiral DRAGNs - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Until recently, it was thought that large double-lobed radio sources are always hosted by massive elliptical galaxies in the local Universe and that the merger phenomenon responsible for the elliptical morphology is also - responsible for triggering the AGN. Consequently, the existence of spiral galaxies that host double-lobed radio sources (“spiral DRAGNs”) is inconsistent with leading galaxy formation models. However, these systems have been confirmed to exist, - calling into question our current understanding of galaxy formation. This project aims to establish the role of these systems in galaxy formation: either reconciling their existence with current models or challenging the idea of the standard feedback - model. I propose a multi-pronged approach to this project: First, I will study the parsec-scale environment in the immediate vicinity of the AGN and determine whether properties of the central black hole in these spiral hosts are similar to those of - the black holes hosted by elliptical galaxies; Second, I will study the megaparsec-scale environment of spiral DRAGNs to determine whether their environment is responsible for their unique nature. I will achieve the first science goal using Very Long - Baseline Interferometry (VLBI) radio observations. I will achieve the second science goal using a combination of archival and new data at multiple wavelengths. Together these two science goals will enable us to definitively determine whether spiral - DRAGNs are a result of the intrinsic properties of the black hole, a result of their large-scale environment, or a combination of both these factors. Furthermore, I will exploit my role as lead for the Radio Galaxy Zoo project on spiral DRAGNs to - find more of these sources. To-date there have been only four spiral DRAGNs detected. Increasing the sample size is imperative for testing the hypotheses that will be formed in the above two science goals, and enable statistically significant - conclusions to be drawn. - - 2018-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - Spiral DRAGNs - - - H2020-MSCA-IF-2014 - - - 660432 - - - - - THE UNIVERSITY OF MANCHESTER - THE UNIVERSITY OF MANCHESTER - KATHOLIEKE UNIVERSITEIT LEUVEN - - - EUR 1 584 202,30 - - - Radical Solutions for Hysteresis in Single-Molecule Magnets - - - EUR 1 584 202,30 - - - United Kingdom - United Kingdom - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Single-molecule magnets (SMMs) display magnetic hysteresis that is molecular in origin, and these materials have huge potential to be developed as nano-scale devices. The big challenge is to create SMMs that function without - the need for liquid-helium cooling. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - RadMag - - - ERC-2014-CoG - - - 646740 - - - - - UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA - THE UNIVERSITY OF EXETER - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - UNIVERSITEIT TWENTE - FONDAZIONE EDMUND MACH - AEROVISION BV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - VLAAMSE INSTELLING VOOR TECHNOLOGISCH ONDERZOEK N.V. - FORSCHUNGSZENTRUM JULICH GMBH - QUESTUAV LTD - - - EUR 3 062 364,12 - - - Training on Remote Sensing for Ecosystem modElling - - - EUR 3 062 364,12 - - - Italy - United Kingdom - Spain - Netherlands - Italy - Netherlands - Germany - Belgium - Germany - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Understanding and predicting ecosystem functions remains a major challenge in evaluating ecosystem services and biophysical controls on biosphere-atmosphere interactions, as current dynamic vegetation models are still not - capable of grasping the spatial and temporal variability in ecosystem processes. Remote sensing (RS) data at a range of scales from proximal observations to global extent sampling can detect essential changes in plant traits (PTs), biodiversity and - ecosystem functioning, providing a method for scaling-up. However there are still methodological and technical constraints that hamper a systematic incorporation of RS in ecosystem models, including scalability and multi-source data integration - issues. TRuStEE will train a new generation of scientists with complementary and interdisciplinary skills in ecosystem modelling, plant physiology, RS technologies and big data analysis, addressing the specific objectives: 1) to identify essential - biodiversity variables (EBVs) and the link with PTs and ecosystem functional properties (EFPs), inferable from RS, 2) to investigate a completely new avenue for assessing vegetation photosynthetic efficiency from RS measurements of canopy - fluorescence, 3) to assimilate diverse RS data streams with varying spatial and temporal resolution in dynamic ecosystem models and 4) to exploit new satellite missions (e.g. ESA-FLEX, ESA-Sentinels, NASA-GEDI) and EO products for the upscaling of - PTs, EBVs and EFPs. The early stage researchers (ESRs) involved will strongly benefit from the network of internationally recognized scientists and private companies with relevant expertise in these topics. The cooperation program proposed will link - academic and non-academic participants to allow the circulation of ESRs giving them the opportunity to become new research and innovation leaders in the most cutting edge sophisticated technologies in the field, increasing their employability in both - academic and private sectors. - - 2020-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Italy - - - TRuStEE - - - H2020-MSCA-ITN-2016 - - - 721995 - - - - - THE UNIVERSITY OF MANCHESTER - THE UNIVERSITY OF MANCHESTER - - - EUR 149 924 - - - A compact radioisotope dating device for rapid sample analysis - - - EUR 149 924 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The FNPMLS project (ERC n.648381) has successfully demonstrated that resonance ionization spectroscopy can be performed efficiently and with high resolution on an accelerated beam (CRIS). This novel and versatile methodology - has been used to measure exotic nuclei down to rates of less than 20 atoms/second. In order to achieve these results the CRIS method has had to efficiently remove interference isotopes that would otherwise saturate the detectors. The key advantages - of the method are its high selectivity, interference suppression and compact size. In principle it can be combined with mass spectrometry techniques such as ICP-MS and IRMS to enhance their respective sensitivity by more than three orders of - magnitude in a compact table top device. This would have applications in the industries that utilize radioisotope detection for molecular labelling and dating. We believe that our methodology has the potential to significantly reduce the costs - associated detecting isotopes such as 14C. In this project we will define and develop a commercialization strategy and effective route to market as well as produce a well defined IP position. A prototype device with autosampling capabilities will be - constructed and used for benchmarking and validation tests that will further inform the marketing strategy. The final deliverables of this project will be a package consisting of a working prototype that demonstrates the ability to rapidly analyse - biological samples and a commercialization strategy that has a clearly defined route to market and IP position. - - 2018-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - CompactDating - - - ERC-2017-PoC - - - 768258 - - - - - KOBENHAVNS UNIVERSITET - - - EUR 212 194,80 - - - Why do We Need a Realist Constitutional Theory to Study the Politics of Constitutional Change in the Middle East? - - - EUR 212 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - This research programme aims to make contribution to comparative political and legal theory by studying the recent constitutional transformation in the Middle East in at least three grounds. First, in arguing that a - constitution always comes into being as a result of a historical process and a decision (will), such historical-sociological context and power relations behind the creation of constitutions can be grappled with best by a realist political and legal - theory. A realist approach sees constitutions as the ultimate battleground for the groups competing for power to constitute the foundational norms and values of society. Second, if a constitution is created by a decision, there is always an agency - behind that decision that executes its will power. In democratic theory such agency is being defined as the people, but the people cannot manifest its will without a representative (e.g. a class, constituent assemblies, or conventions). To this end, - a realist approach carefully examines the agency of Islamic political parties so as to understand the peculiarity of the constitution-making in the Middle-East. Peculiarity here is that the recent revolutions brought Islamic parties to government, - but this has only helped destabilizing the new, or present, constitutions and weakening the hope for accommodation of Islamist groups in a liberal democratic and secular constitution. Third, a comparative realist approach examines both the Western - and Islamic sources of legitimacy so as to have a nuanced understanding of the contemporary crises of legitimacy which now dominates the entire region. Such comparative study is necessary because the Western (secular) concepts and institutions such - as constitution, freedom of association, competitive elections, parliamentarianism and liberal rights have already moved from the Western context to other regions, setting the agenda of political discourse. - - 2019-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - Realist - - - H2020-MSCA-IF-2016 - - - 746390 - - - - - THE UNIVERSITY OF MANCHESTER - THE UNIVERSITY OF MANCHESTER - - - EUR 2 337 548 - - - Biocatalytic Amine Synthesis via Hydrogen Borrowing - - - EUR 2 337 548 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Amine containing compounds are ubiquitous in everyday life and find applications ranging from polymers to pharmaceuticals. The vast majority of amines are synthetic and manufactured on large scale which creates waste as well - as requiring high temperatures and pressures. The increasing availability of biocatalysts, together with an understanding of how they can be used in organic synthesis (biocatalytic retrosynthesis), has stimulated chemists to consider new ways of - making target molecules. In this context, the iterative construction of C-N bonds via biocatalytic hydrogen borrowing represents a powerful and unexplored way to synthesise a wide range of target amine molecules in an efficient manner. Hydrogen - borrowing involves telescoping redox neutral reactions together using only catalytic amounts of hydrogen. - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - BIO-H-BORROW - - - ERC-2016-ADG - - - 742987 - - - - - KOBENHAVNS UNIVERSITET - ASTRAZENECA AB - UNIVERSITAETSKLINIKUM FREIBURG - INSTITUTO DE BIOLOGIA MOLECULAR E CELULAR-IBMC - ACADEMISCH ZIEKENHUIS LEIDEN - MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN - USTAV MOLEKULARNI GENETIKY AKADEMIE VED CESKE REPUBLIKY VEREJNA VYZKUMNA INSTITUCE - - - EUR 2 068 409,16 - - - Improving Genome Editing Efficiency (IMGENE) - - - EUR 2 068 409,16 - - - Denmark - Sweden - Germany - Portugal - Netherlands - Germany - Czech Republic - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - - CRISPR genome editing technology is considered to become the greatest technological improvement in biomedical research since the invention of the polymerase chain reaction 25 years ago and pharmaceutical companies as well as - academic research are eager to apply it. However, the efficiency of introducing defined changes into the genome by CRISPR is still low, currently limiting its application in basic research, industry and gene therapy. IMGENE unites expert European - research groups of academia and industry to address by innovative and complementary approaches the low efficiency of precise genome editing using CRISPR technology. To our best knowledge, IMGENE is the only concerted approach to tackle the important - problem of low genome editing efficiency of CRISPR in a multidisciplinary, intersectorial manner. The IMGENE consortium consisting of 6 academic and 1 industrial beneficiary (AstraZeneca), 2 industrial partners (Taconic; MilliporeSigma), and the - patient organization Genetic Alliance, aims to improve the genome editing efficiency of CRISPR by research training of 8 ESRs to unleash the full potential of this technology. Combining complementary knowledge on protein chemistry, molecular biology, - cellular biology, viral vectors, transgenic mice, gene therapy, and bioinformatics present in the network, IMGENE will establish novel tools and protocols for improved CRISPR genome editing efficiency that will be of immediate benefit for health and - life science research, the pharmaceutical industry, and the application of gene therapy. In addition, IMGENE addresses crucial ethical questions related to the application of genome editing technology in animals, plants, and humans, which have to be - solved to gain acceptance by the society. By excellent research training of 8 ESRs on a scientifically and economically highly relevant topic and additional training in transferable skills, IMGENE will educate novel leaders with great career - perspectives in industry and academia. - - 2021-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Denmark - - - IMGENE - - - H2020-MSCA-ITN-2017 - - - 765269 - - - - - THE UNIVERSITY OF MANCHESTER - THE UNIVERSITY OF MANCHESTER - - - EUR 2 498 645 - - - Nanopores for New Molecular Nitrogen Chemistry - - - EUR 2 498 645 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - We will study the adsorption, binding, transport and reactivity of N-containing substrates within the nanopores of functionalized and doped metal-organic framework (MOF) materials. A range of important target molecules (e.g., - NH3, N2H4, N2O, NO, NO2 and N2O4) will be studied in this project, which aims to re-define the molecular chemistry for these energetic N-compounds in confined space, and to develop selective catalytic reduction (SCR) of NOx in the presence of NH3, - urea and hydrocarbons. The PI has extensive experience in the field of coordination chemistry and hybrid materials, and seeks to change research direction to develop new gas phase catalysts and to gain fundamental understanding of molecular - interactions, properties and function of specific energy, environmentally-related substrates within MOFs. Research objectives include the: - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - NANOCHEM - - - ERC-2016-ADG - - - 742401 - - - - - THE UNIVERSITY OF MANCHESTER - - - EUR 183 454,80 - - - Post-transition metal chalcogenides: 2D nanoelectronics and photonics - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Post-transition metal chalcogenides (PTMCs) such as InSe or GaSe are members of the rapidly expanding family of two-dimensional (2D) materials. Unlike graphene, they possess an electronic band gap, enabling electrostatic - confinement of electrons by using local gate electrodes, and therefore the creation of quantum dots (QD). QDs can be employed as the bases for spin qubits, possible building blocks of solid state quantum computers. Recent results of the host suggest - that PTMCs may surpass other gapped 2D crystals in electron mobility, making possible the fabrication of QDs of exceptional quality. Moreover, their near-direct band gap enables their use in photovoltaic, photodetection and LED applications, and - opens the way for interfacing photons with spin qubits, essential in long-distance communication between quantum computers. The proposed objectives entail the realization of electrostatic confinement to study state of the art PTMC QDs, and testing - their viability as spin qubits via magnetoconductance measurements, and also the investigation of the electro-optical response of 2D heterostructures to address single photon to electron conversion in QDs, and possibilities towards application in - communication, sensing and solar power conversion. - - 2019-09-17, ongoing project - - - 2017-09-18 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - PTMCnano - - - H2020-MSCA-IF-2016 - - - 751883 - - - - - THE UNIVERSITY OF MANCHESTER - - - EUR 183 454,80 - - - Gender gap in students’ achievement: the role of social, economic, geographical and cultural variables - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The study of academic achievement as function of ‘gender’ has received an increasing interest. Nevertheless, this topic seems still topical, at least for the following reasons: until now, some explanatory variables have been - picked out but, probably, further unexplored factors exist; 2) the relationship between those factors has not been disclosed yet, i.e. it is not clear if interaction effects between them exist. In particular, the sectorial literature has investigated - gender-related stereotypes’ effects on academic achievement but it has not studied possible interactions between stereotypes and the other variables frequently used to study students’ performance; 3) the inter-national comparison is undoubtedly an - adequate method to deepen the study of gender-based gap. Nevertheless, the big international research institutes use national data, and it is clear that, when we use big data (such as national ones), almost automatically, some dangerous compensations - occur, leading data to a false medium value. Our approach based also on the intra-national comparison is able to avoid those compensations. In fact, the comparisons between macro-geographical clusters produce better data, i.e. data that reproduce the - reality more realistically, with three main consequences: 1) to improve the probability of picking out factors that can explain academic achievement depend on gender variable; 2) to guide local (inter-/national) policies; 3) to produce new data that - can be used in future researches. Moreover, also the cross-national comparison (between macro-geographical areas within different Countries) could produce new important data because, through it, some possible “regularities” across different Countries - can be disclosed, such as, for example, the same interaction effect between stereotypes and social-economic variables, etc. It could be an interesting headway in the field because it could indicate results that are true independently from specific - context. - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - GE.GAP-EDU - - - H2020-MSCA-IF-2016 - - - 752874 - - - - - OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN - OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN - - - EUR 1 713 352,50 - - - Levels and Trends of Health Expectancy: Understanding its Measurement and Estimation Sensitivity - - - EUR 1 713 352,50 - - - Austria - Austria - - - Research Organisations - Research Organisations - - Better health is central to human happiness and wellbeing. It also contributes substantially to economic progress, as healthy populations live longer and are more productive. Accordingly, the EU defined the improvement of - health as a fundamental element of its “Europe 2020” strategy. The corresponding public health policies are assessed on the basis of a structural indicator for “Health Expectancy” (HE). Unfortunately, HE estimates are extremely sensitive to certain - methodological issues of which many are widely ignored. First, the common measurement of population health by the responses to specific survey questions is ambiguous. As a consequence, statistics on levels and trends of HE vary significantly - depending on the underlying survey data and health indicators. Almost completely unrecognized is a second problem: HE estimates are also highly sensitive to particular technical features, e.g. the age range and partitioning selected for analysis and - the technique chosen to add the health dimension to the life table. The efforts that have been hitherto undertaken to improve the estimation of HE focus primarily on the measurement of health with surveys, whereas the effects of the chosen HE - indicator, data and method remain largely unexplored. The central aim of LETHE is to fill these gaps through a systematic exploration of the HE indicator’s sensitivity to these issues. To emphasize the empirical significance of the proposed research, - the effects will be investigated in the context of some major actual research questions, in particular the “compression versus expansion of morbidity” debate and the differences in HE between European populations and subpopulations. Finally, the - project aims to identify the particular health measure that is most strongly associated with people’s actual happiness. These innovative approaches feature the potential to provide not only new insights into the levels and trends of HE, but also - about its main drivers and causation mechanisms. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Austria - - - LETHE - - - ERC-2016-COG - - - 725187 - - - - - THE UNIVERSITY OF MANCHESTER - - - EUR 195 454,80 - - - The use of mass spectrometry and optical methods to determine the influence of cofactors on the structure and stability of proteins - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - This fellowship will use novel instrumentation to define the role of cofactors on the structure and stability of proteins. We have recently adapted a commercially available Synapt ion mobility mass spectrometer to allow it to - perform optical measurements on conformer and mass selected ions, in collaboration with Waters Corp. The heart of this instrument is the ion mobility cell, IM-MS measurements are possible in this instrument, as for any Synapt mass spectrometer, but - uniquely we are able to trap ions that have been conformer selected, to allow optical measurements in a so called ‘photo SRIG’ (stacked ring ion guide). Such optical measurements can take several forms, including IR-spectroscopy, UV/Vis-spectroscopy, - which will provide structural analysis of co-factors and coenzymes, photo-dissociation to sequence the proteins as well as fluorescence to probe global conformations. - - 2020-02-29, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - PHOTO_IMS - - - H2020-MSCA-IF-2016 - - - 750642 - - - - - THE UNIVERSITY OF MANCHESTER - - - EUR 183 454,80 - - - Molecular Robotics for Synthesis and Catalysis - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The aim of this project is to design, synthesize and investigate the operation of synthetic molecular machines capable of performing sophisticated tasks in chemical synthesis. The molecular machines are inspired by biological - systems, where substrates are shuttled between different enzymatic sites, undergoing chemical transformations at each step. Control of substrate position allows for reactions to occur in a specific sequence, with the molecular machine dictating the - selectivity of each successive chemical reaction. The project both seeks to optimize the structure of the molecular machines for use as a synthetic platform and demonstrate their usefulness for synthesis and catalysis in model reactions. The - successful demonstration of this concept would mark the beginning of a fundamentally new approach for the construction of molecules. - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - RoboCat - - - H2020-MSCA-IF-2016 - - - 746993 - - - - - THE UNIVERSITY OF MANCHESTER - THE UNIVERSITY OF MANCHESTER - - - EUR 1 755 278,75 - - - Illuminating Atomic Scale Processes in Liquids and Gases - - - EUR 1 755 278,75 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - EvoluTEM: Illuminating Atomic Scale Processes in Liquids and Gases - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - EvoluTEM - - - ERC-2016-STG - - - 715502 - - - - - THE UNIVERSITY OF MANCHESTER - THE UNIVERSITY OF MANCHESTER - - - EUR 1 965 170,98 - - - Next Steps in Cosmology with CMB Spectral Distortions - - - EUR 1 965 170,98 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The average spectrum of the cosmic microwave background (CMB) has long been known to be extremely close to a perfect blackbody. Yet, several processes, standard and non-standard, exist that may cause deviations from a - blackbody spectrum, commonly referred to as CMB spectral distortions. Classical distortion shapes are known as Compton-y and chemical potential (µ-type) distortions; however, recently it has been shown that more general distortions can be created at - redshifts 10^4 < z < 3×10^5. This makes spectral distortions a unique and powerful probe of different early-universe processes. The immense potential of CMB spectral distortion measurements and their synergies with upcoming CMB anisotropy - studies (Litebird, COrE+, Stage-IV CMB) has identified them as an important future target, with several innovative experimental concepts (e.g., PIXIE, APSERa) being actively discussed by the cosmology community. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - CMBSPEC - - - ERC-2016-COG - - - 725456 - - - - - THE UNIVERSITY OF MANCHESTER - - - EUR 195 454,80 - - - Non-Thermal PLasma Enabled cAtalysis-Separation system for UpgRading biogasto mEthane-NTPleasure - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Biogas (CO2, 15~60 vol.%, CH4, 40~75 vo.l%) is produced by the anaerobic digestion of organic wastes such as sewage, food wastes and landfill, which can produce biomethane as the transport fuel. Therefore, extensive efforts - have been dedicated for the separation of CO2 from biogas to enrich CH4 present. In addition, the further utilization of separated CO2 (e.g. CO2 to methanol or CH4) is also a challenge for directing its carbon cycle and hence reducing the current - greenhouse gas emissions. In this project, an integrated separation-nonthermal plasma (NTP)-catalyst system will be developed to enable the full utilization and valorisation of biogas. The system will be based on selective capture of CO2 from the - biogas stream using ultra-thin SAPO-34 zeolite membranes (~1 μm thickness) and the subsequent NTP-assisted catalytic CO2 methanation on Ni- and/or Co-based catalysts supported on 5A zeolite membrane (~3 μm thickness). The integrated design combining - CO2 capture with CO2 methanation at ambient temperature will be an excellent candidate for further exploitation in the industrial scale biogas upgrade process. This project will also use transient kinetics and advanced in-situ characterization - methods to understand the reaction mechanism and nature of the active site, including steady-state isotope kinetic analysis, short-time-on-stream diffuse reflectance infra spectroscopy and near ambient pressure X-ray photoelectron spectroscopy, etc. - - 2020-01-14, ongoing project - - - 2018-01-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - NTPleasure - - - H2020-MSCA-IF-2016 - - - 748196 - - - - - THE UNIVERSITY OF MANCHESTER - - - EUR 269 857,80 - - - Stimuli-Responsive Two-Dimensional Materials for Renewable Energy - - - EUR 269 857,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - I will engineer van der Waals (vdW) heterostructures of two-dimensional (2D) materials with tuneable electrochemical response for exploitation in renewable energy applications. These heterostructures, which are constructed by - stacking 2D crystals on top of each other, have been attracting increasing attention in solid-state physics, optoelectronics, and photonics but their full potential in electrochemical applications such as energy storage, conversion, and sensing - remains completely unexploited. I will control their electrochemical response by external stimuli including electric field, strain, and illumination. In order to succeed, I will first develop a solid understanding of the unexplored key - electrochemical properties of 2D materials and their dependence on these stimuli. I will fully exploit my recent experience in 2D materials’ research and the access to the world-class nanofabrication and characterisation facilities and scientific - expertise at Cornell University, the University of Manchester, and National Physical Laboratory. - - 2020-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - 2DMAT4ENERGY - - - H2020-MSCA-IF-2016 - - - 746685 - - - - - THE UNIVERSITY OF MANCHESTER - THE UNIVERSITY OF MANCHESTER - - - EUR 2 926 425 - - - Correlative tomography - - - EUR 2 926 425 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Proposal summary (half page) - - 2021-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - CORREL-CT - - - ERC-2015-AdG - - - 695638 - - - - - THE UNIVERSITY OF MANCHESTER - THE UNIVERSITY OF MANCHESTER - - - EUR 149 817 - - - An ultra compact greenhouse gas remote sensing system for ranges between 500 and 2000 m - - - EUR 149 817 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The CO2Volc project (ERC n.279802) has produced an active remote sensing instrument based on the differential absorption LIDAR principle, called CO2DIAL. It is designed to measure column averaged CO2 concentrations for path - lengths between 500 and 2000 m. A key advantage over other open-path techniques is that no retroreflector or separate active source is required for fence-line monitoring. It therefore fills a key operational gap in CO2 sensing technologies. In - addition, through a laser replacement, the instrument can be used to measure also CH4, allowing both main carbon gas species to be quantified, and producing the name of this project, CarbSens. An affordable greenhouse gas (GHG) sensing platform with - spatial coverage of 2000 m that fits into a backpack, can be mounted on an aircraft, car, mast or even a drone would have a wide variety of commercially attractive applications. These include efficient monitoring of CO2 leakage from CO2 storage sites - or urban traffic, quantification of fugitive CH4 upon hydraulic fracturing (fracking), CH4 leakage from pipelines or biogas tanks, or refining regional GHG budgets for improved climate modeling. A system with the features of the CO2DIAL is not - commercially available. We believe that our technology has the potential to create a new market for affordable, man-portable remote gas sensors, and carbon quantification services. In the initial project phase we will define an adequate - commercialization strategy, focusing on user groups in the hydrocarbon and carbon sequestration industries. A commercial prototype will then be derived from the CO2DIAL. A focus will be to make the system affordable (<40 k€) and even more compact - and lightweight (< 10 kg) to arrive at an instrument that is suitable for a large group of users. The final goal of the proposal is to produce a portfolio consisting of a working commercial prototype and a marketing strategy, including either - secured licensing or the initiation of a spin-out company. - - 2018-06-30, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - CarbSens - - - ERC-2016-PoC - - - 727626 - - - - - THE UNIVERSITY OF MANCHESTER - THE UNIVERSITY OF MANCHESTER - KAROLINSKA INSTITUTET - - - EUR 1 999 337,50 - - - Children and Adolescents with PaRental mental Illness: Understanding the ‘who’ and ‘how’ of targeting interventions - - - EUR 1 999 337,50 - - - United Kingdom - United Kingdom - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - At least 10% of mothers and 5% of fathers have a mental illness. Family, educational and social lives of children and adolescents with parental mental illness (CAPRI) are disrupted by deprivation and repeated hospitalisation. - This is an urgent political and public health concern. The Child and Adolescent Mental Health in Europe (CAMHEE) report urges us ‘to acknowledge and attend to the needs of children and families with parental mental health... ’ recommending better - information on CAPRI risks and resilience so interventions can target those at highest risk. This groundbreaking interdisciplinary programme exploits my unique combination of expertise in epidemiology and neuroscience to deliver on CAMHEE objectives - for CAPRI. - - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - CAPRI - - - ERC-2015-CoG - - - 682741 - - - - - THE UNIVERSITY OF MANCHESTER - THE UNIVERSITY OF MANCHESTER - - - EUR 149 662 - - - Enhancing OLED device performance using Fused Borylated Materials - - - EUR 149 662 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Organic Light Emitting Diodes (OLEDs) are attractive for use in high efficiency illumination and flexible displays. The current state of the art OLED materials use Ir or Pt based phosphorescent materials, which whilst - achieving impressive efficiencies have significant cost, and supply issues associated with rare precious metals. Metal free OLEDs are preferable based on low relative cost and ease of fabrication but to date have not been competitive with Ir / Pt - based OLEDs. This is because metal free OLEDs have relatively low efficiency as light emission is due to fluorescence inherently limiting the systems to 25% of excitons. A new approach has now enabled metal free OLEDs to break this efficiency barrier - – using the phenomena of thermally activated delayed fluorescence (TADF). However, TADF emitters in the deep red / Near infra red (NIR) region of the spectra (desired for applications in optical communications, night vision devices and sensors) are - rare and currently sub-optimal. - - 2018-01-31, closed project - - - 2016-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2015 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - B-Brighter - - - ERC-2015-PoC - - - 713368 - - - - - THE UNIVERSITY OF MANCHESTER - - - EUR 195 454,80 - - - Russian Nationalism and the Ukraine Crisis: The Impact of Nationalist Actors on Russian Foreign Policy - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - As nationalist sentiments are on the rise among broader Russian public, nationalist actors may exercise a more significant role in Russian politics. The main objectives of RUSNAT are: 1) to analyse the impact of the events in - Ukraine on representative organizations of grassroots nationalism in Russia; 2)to analyse the ideologies of Russian nationalists and the Russian government with respect to the events in Ukraine;3)to develop a theoretical and conceptual framework - appropriate for the analysis of the impact of Russian nationalists’ activism on the government’s foreign policy towards neighbouring countries with Russian populations, e.g. the Baltic states. They will be achieved through Discourse Analysis, - Critical Discourse Analysis and close reading of primary sources generated by nationalists and representatives of Russian foreign policy from 2014 to 2016. I will construct a database covering nationalist frames, elite discourse (civic, ethnic, - imperialist), and nationalist disruptive events. The influence of nationalists will be considered as positive if a nationalist frame is adopted by the elite discourse at a later date and if elite discourse changes after sudden disruption events - organized by the nationalists. This research offers insight into the influence of nationalist actors on policy-making in post-communist societies; it helps assess the extent to which in non-democratic contexts foreign policy is driven by nationalist - ideals in its initial phases; it contributes to our understanding of Russia’s relations with neighbouring countries with Russian populations and with the European Union as a geostrategic partner with whom Russia shares this neighbourhood; and, it - will help us understand whether the growing influence of nationalist actors directly encourages the radicalization of Russian policies in near abroad. This is relevant for the design and implementation of EU policies regarding its Eastern - neighbourhood and strategic partnership with Russia. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - RUSNAT - - - H2020-MSCA-IF-2016 - - - 752387 - - - - - THE UNIVERSITY OF MANCHESTER - THE UNIVERSITY OF MANCHESTER - - - EUR 3 488 955,91 - - - Discovering Fast Transients and Pulsars with MeerKAT for Cosmology and to Test the Laws of Gravity - - - EUR 3 488 955,91 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Short duration bursts of cosmic radio emission provide us with a potent tool for studying the extremes of physics. In the form of periodic pulses from pulsars they can be used as precision instruments to test theories of - gravity, understand the emission processes and the equation of state of ultra-dense matter. In the form of transient bursts we can use them to study the physics governing explosive events such as gamma-ray bursts, merging neutron stars, annihilating - black holes or hitherto unknown phenomena. Observing how these bursts are affected by their passage through the distant Universe allows us to probe its physical state. To harness the combined power of periodic and bursting radio sources to explore - physics beyond that possible in a terrestrial laboratory I propose MeerTRAP: Meer (more) TRAnsients and Pulsars, a project to continuously use the MeerKAT telescope to search the radio sky for pulsars and fast transients and to rapidly and accurately - locate them. Utilising the excellent sensitivity and sky coverage of MeerTRAP my team will discover many rare and scientifically important pulsar types: relativistic binaries, intermittent emitters, transitioning systems. Current radio telescopes - have only explored the tip of the transients "iceberg" and MeerTRAP will transform our knowledge of these manifestations of extreme physics. It will detect hundreds of new bursts, which will all be well localised, allowing us to identify hosts and - distances, greatly enhancing their use as cosmological probes. Localisation also enables measurement of their true fluxes, polarisation and spectral indices which are all crucial to identify their origin. To achieve this we will design, implement and - exploit state-of-the-art hardware and software. We will also use the MeerLICHT optical telescope, which will track MeerKAT, to give us a crucial glimpse of the optical sky immediately before and after any radio transient to further constrain their - origin and the associated physics. - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - MeerTRAP - - - ERC-2015-AdG - - - 694745 - - - - - THE UNIVERSITY OF MANCHESTER - - - EUR 233 811 - - - The invisible city. Mapuche mapping of Santiago de Chile. - - - EUR 233 811 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The proposed research explores experiences of urban space among young indigenous Mapuche living in Santiago de Chile, in order to make visible indigenous subjects whose daily lives, collective concerns and social circumstances - are often relegated to the margins of policy making and public interest. It seeks to research the impact of displacement and social exclusion on indigenous youth, as well as offer a means of intervention. The project will identify a set of mutually - negotiated research aims alongside young Mapuche, developing a series of collaborative and participatory methods, including mapping, video and exhibition making, to offer a better understanding of indigenous experiences of the city as a kind of “in - betweeness” - as expressed by the term Mapurbe, from mapu (earth) and urbe (city) - used to symbolize the on-going negotiation of marginality and displacement from the ancestral territory. The outcome of the collaborative research will be used to - address the relationship with non-Mapuche citizens through two exhibitions (in Chile and Europe), offering young Mapuche an opportunity to make an active intervention into public discourse. The proposed research thus aims to apply theoretical - knowledge, collaborative methods and modes of representation to issues of critical social interest in ways that are directly applicable to other context within Latin America and across Europe. The necessary training-through-research will be at the - Instituto de Estudios Urbanos y Territoriales - Pontificia Universidad Católica (Chile), and at the Granada Centre for Visual Anthropology - University of Manchester (UK). This will provide the researcher with theoretical and technical competencies - in Urban Studies and Visual Anthropology. The proposed research will contribute to the strengthening of European networking at an interdisciplinary and inter-continental level, building an international dialogue that will have positive and practical - impacts on the European Research Area. - - 2020-02-29, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - MAPS-URBE - - - H2020-MSCA-IF-2015 - - - 707537 - - - - - THE UNIVERSITY OF MANCHESTER - THE UNIVERSITY OF MANCHESTER - - - EUR 2 494 328,75 - - - Prenylated-flavins: Application and Biochemistry - - - EUR 2 494 328,75 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Our group has recently discovered a new type of cofactor: a prenylated-flavin that has azomethine ylide properties. This cofactor is an integral part of the widespread ubiD/ubiX system. The latter is implicated in the - non-oxidative reversible decarboxylation of aromatic substrates, and plays a pivotal role in bacterial ubiquinone biosynthesis or microbial biodegradation of aromatic compounds. We established UbiX acts as a novel flavin prenyltransferase, linking a - dimethylallyl moiety to the flavin N5 and C6 atoms. Formation of the holo-UbiD enzyme involves oxidative maturation of the new cofactor, creating the novel azomethine ylide moiety. The dipolarophile substrate binds directly above the azomethine ylide - group, and our data strongly suggests 1,3-dipolar cycloaddition chemistry supports reversible decarboxylation in these enzymes. While 1,3-dipolar cycloaddition is commonly used in organic chemistry, this presents the first example of an enzymatic - 1,3-dipolar cycloaddition reaction. Our model for UbiD catalysis hints at new routes in alkene hydrocarbon production or aryl (de)carboxylation. - - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - pre-FAB - - - ERC-2015-AdG - - - 695013 - - - - - THE UNIVERSITY OF MANCHESTER - THE UNIVERSITY OF MANCHESTER - - - EUR 1 995 655,76 - - - Fundamental Physics Using Black Widow, Redback and Transitional Pulsar Binaries - - - EUR 1 995 655,76 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - I will use an innovative coupled approach to facilitate a paradigm shift in the use of neutron stars as a probe of high energy physics. The compactness, rapid rotation and large magnetic fields of neutron stars make them, - along with black holes, the most extreme objects found in our Universe. Neutron stars are therefore formidable laboratories to study fundamental physics, as they allow us to probe regimes simply unavailable to Earth-based experiments. However, in - spite of their potential utility, there are still a number of important outstanding questions in this field. Key amongst these are: What is the neutron star equation of state? How do neutron stars become the fastest rotating stellar objects in the - Universe? How do millisecond pulsars affect their environment? Answering these questions has a broad multi-disciplinary impact, far beyond the field of neutron star research alone; however, at present our ability to answer these questions is limited - by cherry picking individual objects for study. In this proposal I describe how I will move away from the biases inherent in the idiosyncratic nature of particular sources to a comprehensive population analysis, and specifically, how I will use a - particular class of neutron star systems, known as “spider binaries”, to discover the most massive and the fastest spinning neutron stars that exist. Such extreme cases are of crucial importance for constraining the neutron star equation of state and - thus determining the boundary for stellar mass black hole formation. This knowledge in turn can tell us about possible phase transitions of matter at high densities and provide observable quantities that can then be tested against Earth-based - experiments, feeding back into high energy physics theories. I will achieve these goals through a transformational observational approach to finding new spider systems and drawing on innovative techniques from other fields to improve parameter - estimation. - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - Spiders - - - ERC-2016-STG - - - 715051 - - - - - THE UNIVERSITY OF MANCHESTER - THE UNIVERSITY OF MANCHESTER - - - EUR 1 997 219 - - - Delivering on the Promise of Measuring Dark Energy from Cosmic Lensing - - - EUR 1 997 219 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The apparent gravitational distortion of distant galaxies, ‘cosmic lensing’, allows us to map dark matter and hence unveil the nature of the mysterious dark energy. I will develop novel approaches to cosmic lensing and use - these to place constraints on dark energy using the Dark Energy Survey (DES). Themes 1 and 2 address key systematic effects crucial for the extraction of cosmology in theme 3. Theme 1: The lensing community has spent two decades trying to find the - perfect galaxy shape measurement method. We will take a unique approach by translating a technique common in particle physics and the CMB to lensing: we will simulate images matched to observed galaxy positions and shapes, and vary lensing to - accurately calibrate shapes. We will make the code public and use it to produce the final public DES shear catalogues. Theme 2: We will exploit my innovative and successful program of coordinated international challenges from shear measurement and - apply it to mitigating galaxy intrinsic alignments (IA). I have shown that knowledge of IAs is essential for leveraging the potential of cosmic lensing for cosmology and described a mitigation method, but this needs to be tested on simulations. I - will coordinate international IA simulation efforts and identify the optimum method for removing intrinsic alignments and apply it to the DES data. Theme 3: We have developed a skeleton software framework for cosmology, CosmoSIS. We will write - modules for cosmology from imaging data incorporating the main systematic effects, and use CosmoSIS to produce the final constraints on cosmology from DES lensing. We will incorporate constraints on sterile neutrinos from particle physics for the - first time. If the current tensions between cosmic lensing the CMB are confirmed by this work we will have discovered the need for new physics. Furthermore, the work in this proposal will place us in prime position to exploit the main cosmology - surveys of the next decade (LSST, Euclid, WFIRST). - - 2021-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - COSMIC LENS - - - ERC-2015-CoG - - - 681431 - - - - - THE UNIVERSITY OF MANCHESTER - - - EUR 195 454,80 - - - Structural Engineering of 2D Atomic Planes towards Task-Specific, Freestanding Superstructures through Combined Physical-Chemical Pathway - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The research on 2D nanomaterials has boomed since the discovery of graphene by professors Geim and Novoselov in 2004. After a decade of steady development, the available library of 2D crystals is highly rich including graphene - derivatives, hexagonal boron nitride, many chalcogenides and various oxides. However, the technological advances and urgent environmental and sustainable energy issues such as CO2 capture and separation, energy storage and conversion (photovoltatic - system, supercapacitor etc) call for advanced materials with not only properties of individual layers but also new functionalities. Particularly, researches on superstructures with unique properties such as amphiphilicity still remain blank. - Physically, it is now possible to create such hybrid superstructures by placing different 2D crystals on top of each other in a designed sequence; while engineering the 2D units through a chemical way endows a high flexibility in surface chemistry - tailoring and increase the mechanical stability due to the strongly bonded interface. Taking these into consideration, here we propose a combined chemical-physical pathway to engineer task-specific, mechanically freestanding superstructures based on - 2D atomic planes in a simple and scalable manner. Three new material concepts are proposed including amphiphilic superstructure (hydrophilic outer layer and hydrophobic inner layer), gas selective superstructure (CO2-phililc outer layer and gas shape - selective inner layer) and flexible superstructure with outer layer functionalized with metal oxide nanoparticles confined in ordered mesopores and inner conductive graphene. The obtained superstructures with these structural features will be - oriented environmental and sustainable energy issues such as CO2 capture and separation, water purification and flexible electrode. Finally, structure-performance relationship will be unraveled fundamentally. - - 2018-07-24, ongoing project - - - 2016-07-25 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - CHEPHYTSSU - - - H2020-MSCA-IF-2015 - - - 707096 - - - - - THE UNIVERSITY OF MANCHESTER - - - EUR 183 454,80 - - - Bimetallic catalytic arylation of simple arenes - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The development of new methodologies for the preparation of biologically and industrially interesting compounds remains one of the fundamental challenges in chemistry. Aryl-aryl bond formation is one of the most important - tools in modern organic synthesis. These biaryl motifs are very often found in pharmaceutical, agrochemicals, organic materials and natural products. Given the abundance of C–H bonds in organic molecules, the selective activation and use of these - bonds in controlled synthetically useful transformations is an immensely important topic. In this context, direct C–H arylation has emerged as a powerful methodology for the synthesis of biaryls. However, in most methodologies described so far, the - arene substrate must fulfil certain requirements such as containing strong electron-withdrawing or electron-donating groups, or bearing special directing groups. Substrates lacking this feature either are unreactive or must be used in large excess - (often as solvents). The coupling of ‘simple arenes’, which are not considered as pi-electron-deficient or -rich remains challenging. - - 2018-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - BiMetArylation - - - H2020-MSCA-IF-2015 - - - 702177 - - - - - THE UNIVERSITY OF MANCHESTER - - - EUR 195 454,80 - - - Transition Friction in the Ecuadorian Amazon: A Green Economy Ethnography - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The dominant framing of humanity’s current predicament emphasizes ‘planetary limits’ and impending environmental collapse, with ‘green economy’ strategies as a necessary response. Initiatives for transitions to ‘green’ - production and consumption patterns are emerging and multiplying, at different scales and all over the world. The visions of ‘sustainability’ underpinning these initiatives are diverse, and their heterogeneous socio-ecological effects raise urgent - questions of justice. With a focus on the power dynamics and inequalities of green transition initiatives, TRANSITION-FRICTION will cross-fertilise three literatures – political ecology, transition studies and ethnographies of global connections. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - United Kingdom - - - TRANSITION-FRICTION - - - H2020-MSCA-IF-2015 - - - 707017 - - - - - THE UNIVERSITY OF MANCHESTER - - - EUR 183 454,80 - - - Visible Light-Mediated Synthesis of Nitrogen-Centered Radicals: New Reactivity via Photoredox Catalysis and Electron-Transfer Complexes - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Nitrogen-containing molecules are among the most important class of compounds due to their relevance as medicines, agrochemicals, organic materials and dyes. Nitrogen-centered-radicals are a class of very versatile synthetic - intermediates with great potential in the synthesis of N-containing molecules. However, to date, difficulties associated to their generation have severely limited their use and exploitation. Here we propose the development of two conceptually novel - and general ways to prepare Nitrogen-centered radicals using visible light as sustainable and inexpensive source of energy. These processes will capitalize on recent developments in the host group that has disclosed the use of easy-to-make aryl - oximes for the organocatalytic generation of iminyl radicals. This proposal seeks to substantially expand this visible light chemistry through the development of methods for the generation and use of any known Nitrogen-centered radical. The power of - this approach will be demonstrated by the short synthesis of the complex molecule legionaminic acid, responsible for the spread of hospital-acquired infections. Furthermore, these methods will be integrated with other reaction platforms that, taking - advantage of visible light as source of energy, will engage the Nitrogen-centered radical in new reactivity modes, to allow novel and powerful multicomponent reactions. - - 2019-01-31, ongoing project - - - 2017-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - NCR - - - H2020-MSCA-IF-2015 - - - 703238 - - - - - JOINT INSTITUTE FOR VERY LONG BASELINE INTERFEROMETRY AS A EUROPEAN RESEARCH INFRASTRUCTURE CONSORTIUM (JIV-ERIC) - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CHALMERS TEKNISKA HOEGSKOLA AB - DEPARTMENT OF SCIENCE AND TECHNOLOGY - ISTITUTO NAZIONALE DI ASTROFISICA - MINISTERIO DE FOMENTO - SKA ORGANISATION - STICHTING ASTRON, NETHERLANDS INSTITUTE FOR RADIO ASTRONOMY - STICHTING INTERNATIONAL LOFAR TELESCOPE - TECHNISCHE UNIVERSITAET MUENCHEN - UNIVERSITY OF LEEDS - THE UNIVERSITY OF MANCHESTER - - - EUR 2 983 682,50 - - - Joining up Users for Maximising the Profile, the Innovation and the Necessary Globalisation of JIVE - - - EUR 3 312 308,59 - - - Netherlands - France - Sweden - South Africa - Italy - Spain - United Kingdom - Netherlands - Netherlands - Germany - United Kingdom - United Kingdom - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - “Joining up Users for Maximising the Profile, the Innovation and the Necessary Globalisation of JIVE” (JUMPING JIVE) aims to prepare and position European Very Long Baseline Interferometry (VLBI) for the SKA era, and to secure - the role of JIV-ERIC in the European and global landscape of Research Infrastructures. - - - 2021-01-31, ongoing project - - - 2016-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-03-2016-2017 - Individual support to ESFRI and other world-class research infrastructures - - - CSA - Coordination and support action - - - Netherlands - - - JUMPING JIVE - - - H2020-INFRADEV-2016-1 - - - 730884 - - - - - THE UNIVERSITY OF MANCHESTER - - - EUR 183 454,80 - - - Olfactory processing of repellent and attractive stimuli in the brain of Drosophila - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Mosquito-borne diseases present one of the greatest threats to human health. Mosquitoes find humans by detecting human body odour and CO2 with their olfactory system. This project addresses the fundamental and still unresolved - question of how odorant valence is coded in the brain and why odorants that are attractive (positive valence) at low concentrations, switch to being repulsive (negative valence) at high concentrations. This phenomenon of valence switch is well - conserved throughout the animal kingdom and represents an ideal paradigm to address a key question in the neurosciences, i.e. how information processing in neuronal networks leads to behavioural responses. To advance the understanding of valence - coding and olfactory processing, the Experienced Researcher (ER) will capitalise on her detailed knowledge of the evolutionary well conserved olfactory system of the fruitfly Drosophila melanogaster, using its powerful genetic and experimental - approaches (e.g. Riabinina et al, 2015, Nature Methods; Gao et al, 2015, Nature Neuroscience). The key goal of the project is to identify patterns of neuronal activity that code for odorant valence. To achieve this goal, we will record responses of - small subsets of genetically labelled second-order olfactory neurons by patch-clamp while activating olfactory receptor neurons optogenetically or by odorants of known behavioural valence. We will apply statistical and machine learning techniques to - detect parameters of neuronal activity, indicative of odorant valence. - - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - United Kingdom - - - OPRAS - - - H2020-MSCA-IF-2015 - - - 701109 - - - - - THE UNIVERSITY OF MANCHESTER - - - EUR 195 454,80 - - - Fast particle-based time integrator for incompressible flows simulations - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The FastFlowSim project’s aim is to develop a fast and accurate particle-based time integrator for the simulation of incompressible flows. The developments will be done within the framework of the particle finite element - method and using a semi-Lagrangian semi-implicit formulation of the flow equations. The principal strategy used to attain a faster method is to push further the stability limit of the time integrator which allows us to take larger time steps without - deteriorating the accuracy. - - 2018-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - FastFlowSim - - - H2020-MSCA-IF-2015 - - - 702138 - - - - - THE UNIVERSITY OF MANCHESTER - - - EUR 183 454,80 - - - Unsymmetric diborane(4) compounds for small molecule activation and B-B coupling - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Organoboron complexes are ubiquitous in synthesis due to their utility in functional group transformations and the Nobel Prize winning Suzuki-Miyaura reaction. Furthermore, the advent of frustrated Lewis pair chemistry and BB - multiple bonds has demonstrated that organoboron compounds can activate small molecules (e.g., CO) and sigma bonds (including H2), reactivity previously thought to be the domain of transition metal catalysts. As part of the renaissance in organoboron - chemistry diborane(4) compounds (R2B-BR2) have received considerable interest, particularly that react as boryl anion equivalents. Recent unpublished work at UNIMAN has developed an efficient, scalable route to a synthetically useful unsymmetric - diborane(4) compound, specifically (RO)2B-BCl2(NHC), (1, NHC = N-heterocyclic Carbene). The DIBOR project will exploit this breakthrough using 1 (and new congeners synthesised in this fellowship) as key precursors to; - - 2018-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - DIBOR - - - H2020-MSCA-IF-2015 - - - 703227 - - - - - THE UNIVERSITY OF MANCHESTER - THE UNIVERSITY OF MANCHESTER - - - EUR 149 250 - - - A new architecture for visual display technology based upon recent advances in our understanding of visual physiology. - - - EUR 149 250 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The last twenty years has seen a huge improvement in the quality of images produced by commercial visual display units. Nevertheless, they still do not fully recreate the range of sensations we experience during natural - vision. We have designed a prototype visual display that will allow us to take advantage of recent developments in visual neurophysiology to address that limitation. We request funds to construct this prototype and explore its performance as a - necessary proof of concept for its commercialisation. - - 2017-05-31, closed project - - - 2015-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2015 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - MeloVDU - - - ERC-2015-PoC - - - 692645 - - - - - THE UNIVERSITY OF MANCHESTER - - - EUR 496 607,50 - - - Metrology of Carbohydrates for Enabling European Bioindustries - - - EUR 496 607,50 - - - United Kingdom - - - Higher or Secondary Education Establishments - - CarboMet will foster and drive collaboration, cross-fertilisation and communication among stakeholders to facilitate a uniform approach to the metrology and/or measurement of carbohydrates for exploitation in - biopharmaceuticals, diagnosis of disease and precision medicine, food and personal care and sustainable material BioIndustries. This will be achieved through a consolidated approach towards the modification of key emerging technologies or - identification of radically new technologies currently unforeseen by technology roadmaps. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-02-2016 - FET-Open Coordination and Support Actions - - - CSA - Coordination and support action - - - United Kingdom - - - CARBOMET - - - H2020-FETOPEN-2-2016 - - - 737395 - - - - - THE UNIVERSITY OF MANCHESTER - THE UNIVERSITY OF MANCHESTER - - - EUR 2 171 622,89 - - - Elucidating the role of ultraviolet radiation in melanoma - - - EUR 2 171 622,89 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Melanoma incidence continues to increase across Europe and compared to other cancers, it disproportionately affects young people, causing a significant loss in life-years in those affected. Ultraviolet radiation (UVR) is the - only environmental risk factor in melanoma, but the underlying genetic constitution of the individual also plays an important role. However, our knowledge of the gene-gene and gene-environment interactions in melanomagenesis is still very limited and - here we will use various cutting-edge technologies to investigate the role of UVR in melanoma initiation and progression. We have developed mouse models of UVR-driven melanoma that closely mimic UVR-driven melanoma in humans and these provide an - unprecedented opportunity to dissect how different wavelengths and patterns of UVR exposure affect melanomagenesis. We propose a multidisciplinary programme of work to examine how host genetic susceptibility factors and responses such as DNA damage - repair and inflammation affect melanoma development and progression following UVR exposure. We will integrate knowledge from our animal experiments with epidemiological, histopathological, clinical, and genetic features of human tumours to improve - stratification of human melanoma and thereby assist clinical management of this deadly disease. Our overarching aim is to develop a validated stratification approach to melanoma patients that will assist in the development of effective public health - campaigns for individuals at risk across Europe. - - 2021-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - MMUVR - - - ERC-2014-ADG - - - 671262 - - - - - THE UNIVERSITY OF MANCHESTER - - - EUR 195 454,80 - - - Cyclic Arylenevinylene Polymers - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Research work at the University of Manchester (UNIMAN) has developed an efficient synthetic method to prepare arylenevinylene polymers with control of molecular weight and end-group functionality by the ring-opening metathesis - polymerization (ROMP) of strained 1,9-cyclophanedienes. The CyclAr project will use this methodology to deliver conjugated polymers of novel topologies, including rings, 8-shapes, trefoils and others. Macromolecular rings will be prepared by ring - expansion metathesis polymerization (REMP) using a tethered ruthenium carbene complex and more complex topologies from telechelic polymers prepared from a bifunctional ruthenium carbene complex. Electron rich (p-type) and electron poor (n-type) - polymer topologies will be prepared from the appropriate functionalised cyclophanedienes and topological heterojunctions examined. These molecules will be screened for their photovoltaic performance as the novel molecular topologies can lead to an - enhanced charge separation and fewer loss mechanisms - key factors in achieving higher power conversion efficiency in OPVs. The synthetic methodology to be adopted is novel and application of these topological arylenevinylene polymers as - semiconducting materials in device fabrication is unprecedented. - - 2018-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - CyclAr - - - H2020-MSCA-IF-2015 - - - 703125 - - - - - AKZO NOBEL CAR REFINISHES BV - THE UNIVERSITY OF MANCHESTER - - - EUR 1 276 871,40 - - - Sustainable Organic Coatings for Corrosion Protection - - - EUR 1 276 871,40 - - - Netherlands - United Kingdom - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - BACKGROUND / NEED: - - 2020-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-EID - European Industrial Doctorates - - - Netherlands - - - SUSTICOAT - - - H2020-MSCA-ITN-2016 - - - 721451 - - - - - THE UNIVERSITY OF MANCHESTER - THE UNIVERSITY OF MANCHESTER - - - EUR 2 294 781 - - - Developing and delivering neurocomputational models to bridge between brain and mind. - - - EUR 2 294 781 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The promise of cognitive neuroscience is truly exciting – to link mind and brain in order to reveal the neural basis of higher cognitive functions. This is crucial, scientifically, if we are to understand the nature of mental - processes and how they arise from neural machinery but also, clinically, if we are to establish the basis of neurological patients’ impairments, their clinical management and treatment. Cognitive-clinical neuroscience depends on three ingredients: - (a) investigating complex mental behaviours and the underlying cognitive processes; (b) mapping neural systems and their function; and (c) methods and tools that can bridge the gap between brain and mental behaviour. Experimental psychology and - behavioural neurology has delivered the first component. In vivo neuroimaging and other allied technologies allow us to probe and map neural systems, their connectivity and neurobiological responses. The principal aim of this ERC Advanced grant is to - secure, for the first time, the crucial third ingredient – the methods and tools for bridging systematically between cognitive science and systems neuroscience. - - 2020-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - BRAIN2MIND_NEUROCOMP - - - ERC-2014-ADG - - - 670428 - - - - - THE UNIVERSITY OF MANCHESTER - - - EUR 195 454,80 - - - Novel Electrochemical Exfoliation Approach to the Synthesis of Large Area, Defect-Free and Single Layer Graphene and Its Application in Fuel Cells - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Large area, scalable production of single layer and defect free graphene is important for its use in industrial applications. Currently, common methods used to prepare graphene include micromechanical cleavage, chemical vapor - deposition, and chemical reduction. However, all these methods have their own shortcomings, for example, difficulty in scale-up or poor quality due to significant defects. To address this issue, in this project, we will focus on developing a novel - electrochemical cathodic exfoliation approach to produce high quality graphene. Non-covalent edge-functionalization will be employed to open graphite edges. Upon a negative potential applied on the functionalized graphite electrode, H+ cations from - protic ionic liquid electrolyte will be inserted into graphite interlayers and be reduced to hydrogen gas to further open the edge of graphite, which will facilitate the larger imidazolium cations to intercalate, expand and completely exfoliate - graphite to single layer graphene. This cathodic exfoliation approach is nondestructive to the resultant graphene, and maintains its perfect structure and electronic properties, which will result in high electrochemical stability and benefit the - performance of graphene-based fuel cell electrocatalysts. Finally proton exchange membrane fuel cells will be fabricated with graphene based electrocatalysts above and these are expected to exhibit high power density and long term durability, which - may produce a promising future energy technology. - - 2017-08-16, closed project - - - 2015-08-17 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - GRAPHENERGY3 - - - H2020-MSCA-IF-2014 - - - 660064 - - - - - THE UNIVERSITY OF MANCHESTER - - - EUR 195 454,80 - - - Identification of genes and pathways regulated by the HAT activity of MOZ - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The research programme will comprise the study of the Histone acetyl transferase (HAT) MOZ (Monocytic leukaemia Zinc finger) a critical player in the development and maintenance of the haematopoietic system. In addition, - translocations of MOZ are associated with Acute Myeloblastic Leukaemia. Given the importance of this protein in haematopoiesis and leukaemogenesis, it would be essential to further understand the function of MOZ and in particular to identify the - genes regulated by its HAT activity of MOZ. A mouse line specifically mutated to abrogate the HAT enzymatic activity of MOZ has been developed in the host laboratory, and represents a powerful and unique tool for the study of MOZ HAT activity. Using - Chromatin ImmunoPrecipitation followed by sequencing (ChIP-seq), genome wide targets of MOZ will be determined and the consequences of the deletion of its HAT activity on the epigenetic landscape will be investigated through the survey of several - histone modifications and RNA polymerase II recruitment. The non-histone targets of MOZ will be identified through the SILAC technique. Finally a MOZ murine leukaemic model has been developed, based on the transduction of bone marrow cells with a - retrovirus encoding MOZ-TIF2, one of the fusion proteins involving MOZ. ChIP-seq will be performed in these leukaemic cells to identify genes targeted by MOZ-TIF2 and changes in epigenetic marks at these loci. Overall, this project will provide a - better understanding of MOZ HAT activity in haematopoiesis and leukaemogenesis. Crucially, this project will enable Dr Anne Largeot to obtain and develop a wide range of new and transferable skills through a variety of multidisciplinary training - programs. Relying on the knowledge and expertise of her supervisor and the exceptionally high calibre of the Cancer Research UK Manchester Institute, this project will enable Dr Anne Largeot to achieve her long-term objective of obtaining a - leadership position in a competitive European Institute - - 2017-08-31, closed project | - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - HAT-MOZ-sphere - - - H2020-MSCA-IF-2014 - - - 658625 - - - - - THE UNIVERSITY OF MANCHESTER - - - EUR 195 454,80 - - - Measurement of charm matter-antimatter asymmetries - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Flavour physics, and the study of antimatter in particular, is one of the most exciting fields at the frontier of fundamental physics research. It is driven by the question of what happened to the antimatter after the Big Bang - and is a recognized long-term priority as part of the CERN European strategy for particle physics. Nature provides particles that contain both matter and antimatter quarks as ideal laboratories for the discovery of matter-antimatter asymmetries (CP - violation). This proposal will focus on the least explored of these particles, charm mesons; CP violation discoveries in strange and beauty mesons have already led to Nobel Prizes. - - 2019-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - CharmingAntimatter - - - H2020-MSCA-IF-2015 - - - 704733 - - - - - THE UNIVERSITY OF MANCHESTER - - - EUR 183 454,80 - - - Neural basis of semantic control - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Every form of semantically-driven human behavior is supported by semantic ‘control’, which refers to executive processes that regulate access to semantic knowledge. To understand everyday verbal and nonverbal activities (e.g., - speaking, object use), as well as impairments after brain damage, it is crucial to establish how semantic control is implemented in the brain. - - - 2018-01-31, closed project - - - 2016-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - NBSC - - - H2020-MSCA-IF-2014 - - - 658341 - - - - - THE UNIVERSITY OF MANCHESTER - - - EUR 195 454,80 - - - Fungal resistance to antifungals is promoted by cell heterogeneity - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The number of people who die from fungal infections is estimated to be equivalent to or greater than the numbers that die from either tuberculosis or malaria. There are only 3 classes of antifungal drugs available to treat - these invasive diseases and resistance against these drugs is increasing. In this study I will investigate how antifungal resistance is impacted by cell heterogeneity in the pathogenic fungus Aspergillus fumigatus. The main hypothesis that I will - test is that fungal cell heterogeneity provides subpopulations of cells with greater fitness to resist antifungal treatment. I will determine: (1) which features of three distinct fungal cell types contribute to cell heterogeneity; (2) which cell - types and subpopulations of these cells show highest resistance or survival against antifungals; and (3) the roles of septal plugging and cell ploidy in the mechanistic basis of fungal cell heterogeneity. Cutting edge technologies that will be used - in this study will include: (1) flow cytometry and fluorescence activated cell sorting (FACS) to identify and select cell subpopulations to test their antifungal resistance, (2) automated, high throughput, high content live cell imaging to analyse - the resistance of single cells to antifungals, (3) advanced live-cell imaging techniques including GFP photoactivation and fluorescence recovery after photobleaching (FRAP) to identify septal pore plugging; and (4) laser microdissection to further - analyse septal pore plugging. With these advanced techniques I will study the mechanistic basis of fungal resistance mediated by cell heterogeneity. My results will ultimately show how fungal cell heterogeneity impacts fitness against antifungal - drugs and they will be the starting point for designing novel antifungal therapies that reduce this fitness. - - 2017-05-31, closed project | - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - FUNFIT - - - H2020-MSCA-IF-2014 - - - 659003 - - - - - THE UNIVERSITY OF MANCHESTER - - - EUR 195 454,80 - - - Magnetic Sensors based on Two-Dimensional Materials/Si - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Magnetoresistance sensors based on the change in electrical resistance upon an external magnetic field are widely used in day to day applications. The magnetic sensor industry sells billions of dollars worth of sensors every - year and there is an ever-growing demand for magnetic sensors with high sensitivity, small size, low power consumption and low cost with compatibility with existing electronic systems. The project aims to develop a new class of highly sensitive - magnetoresistance sensors based on doped Si and two dimensional (2D) layered materials, with a focus on single layer graphene and single layer WS2 which could be easily extended to other low dimensional layered materials. This plan will utilize the - advantages of tunnelling through SiO2, gate tunability of 2D materials and the geometry of Si to obtain highly sensitive magnetic sensors from Si, which is very unique and novel. The large magnetoresistance observed in graphene by the applicant's - group (Gopinadhan et al. Phys. Rev. B 88, 195429 (2013)) can be utilized to get an additional positive change in total resistance per unit applied magnetic field for higher sensitivity. Si can be integrated monolithically, in contrast, 2D layered - materials such as graphene possess excellent electrical, thermal and mechanical properties. Its high mobility of carriers are very attractive for high speed applications. The interface between Si and 2D materials are little explored, however there is - an enormous technological interest for applications such as graphene-based transparent electrodes in Si solar cells, high speed non-volatile flash memory, microwave switches, voltage controlled diodes, logic devices etc. Furthermore, most of the - existing magnetic sensors are electron based and the possibility of both n and p type magnetic sensors due to the electric field tunability of 2D materials may provide new applications such as magnetic sensor and diode (p-n junction) in one active - device. - - 2017-08-02, closed project | - - - 2015-08-03 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - 2DSi - - - H2020-MSCA-IF-2014 - - - 659963 - - - - - THE UNIVERSITY OF MANCHESTER - - - EUR 195 454,80 - - - MASS POLITICAL LIFE WRITING - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Self-narration is extraordinarily common in contemporary culture. The practice constitutes an extremely popular literary genre, is widespread on the internet in the form of diaries updated daily by huge numbers of web users, - and is used in organisational training and as a tool in personal therapy education. Employing an interdisciplinary approach – drawing on social history, sociology, semiotics and textual analysis – my research project will examine one of the - "archaeological" elements underpinning this success: the mass political use of the autobiographical form, first by communism and subsequently by feminism after the Second World War, with a focus on the Italian experience. The Italian Communist Party - (PCI) was the largest communist party in the Western world, and Italy’s experience of feminism is one of the most significant on the European continent. Both movements made intense political use of the autobiographical form. The Italian communists - inherited the activist autobiographical framework characteristic of the Bolshevik experience. Self-narration was a prerequisite to joining the PCI until the second half of the fifties; however, this organisational practice became obsolete over the - course of the sixties. The link between autobiographical accounts and political activism was subsequently revived by feminism in the seventies, in the context of consciousness raising groups. The main objectives of the project are the following: A) - to analyse the mass political use of the autobiographical account in Italy since the Second World War; B) to use this analysis to produce an innovative interpretation of the actual success of self-narration. They will be fulfilled through research in - the archives of the PCI and the Italian feminist movement. I will use Italian historical events as a case study to highlight the obscure political origins of a specific activity – self-narration – that unites various contemporary national cultures of - Europe in a transnational manner. - - 2017-08-31, closed project | - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - POLITICALLIFEWRITING - - - H2020-MSCA-IF-2014 - - - 658297 - - - - - THE UNIVERSITY OF MANCHESTER - - - EUR 183 454,80 - - - Deaf life narratives in times of transition. - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The research project concerns deaf people who use a signed language, such as BSL (British Sign Language). It investigates the potential of a culturally familiar practice, storytelling, as a means of promoting agency, - resilience and better well being. Using techniques of narrative therapy, narrative analysis and grounded theory, the project will explore the significance of life story work to enhance well being from a cross cultural perspective, engaging with deaf - migrants from diverse nation states. It will result in a life story instrument, piloted during the study that exploits the visual learning strengths of deaf people and the properties of visual (non-textual) languages through digital media. It extends - current research on narrative methods as a form of cultural brokering and emancipatory methodologies within critical deaf epistemologies. - - 2017-10-31, closed project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - DEALS - - - H2020-MSCA-IF-2014 - - - 656285 - - - - - THE UNIVERSITY OF MANCHESTER - - - EUR 183 454,80 - - - CO2 as a traceless directing group for catalytic meta C-H olefinations - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The development of methods for the transition metal-catalysed functionalization of C-H bonds is revolutionizing synthetic organic chemistry by providing tools to simplify and accelerate the synthesis and modification of a - myriad of known and still unknown organic molecules including aromatic compounds. However, in these processes, the ability to discriminate between C-H bonds for subsequent transformation into other functional groups still remains as a major - challenge. To date, much progress has been made on developing strategies for the ortho-functionalization of arenes, mainly through the derivatization of the substrates with directing groups. meta-Functionalization approaches, on the other hand, are - extremely scarce despite eta-substitution is a widespread motive amongst biologically active molecules. - - - 2017-03-31, closed project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - metaC-Hfunct - - - H2020-MSCA-IF-2014 - - - 656841 - - - - - THE UNIVERSITY OF MANCHESTER - - - EUR 183 454,80 - - - Dam-nations? A study on dams, nation-building and transboundary water relations through case-studies from Ethiopia and Tajikistan - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The aim of DAM-NET is to enable the Future Fellow (FF) to carry out a state-of the art research project, investigating how ruling elites can use the symbolic value of a large hydraulic infrastructure to construct and - disseminate their particular idea of the nation and legitimize their hold on power. The study will expand on the largely unexplored link between water and social power, bringing new insights into the analysis of transboundary water relations and on - the role that discourse and nationalism play in water politics. Throughout a varied set of activities, the project will allow transfer of knowledge and the training of the FF, thus improving his employability and career perspectives. - - 2017-08-31, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - DAM-NET - - - H2020-MSCA-IF-2014 - - - 654861 - - - - - THE UNIVERSITY OF MANCHESTER - THE UNIVERSITY OF MANCHESTER - - - EUR 1 846 541,99 - - - Fundamental nuclear properties measured with laser spectroscopy - - - EUR 1 846 541,99 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The prime research theme of this project is the study of short-lived exotic nuclei with laser spectroscopy. Over the next 5 years my team will study the role of three-nucleon forces and their associated influence on nuclear - structure and the limits of nuclear existence. This work will investigate the interplay between tensor and central forces and the associated effect on quantum shells in exotic nuclear systems. This proposal will study how the shape of the nucleus is - modified at the limits of nuclear existence. We will use innovative laser spectroscopy methods to achieve these goals. The project will be carried out at the ISOLDE facility, CERN, which is the premier radioactive beam facility at the precision - frontier. The proposed research activity closely matches the NuPECC (Nuclear Physics European Collaboration Committee) 2010 Long Range Plan. The wider scientific impact of this research will influence modelling explosive stellar processes and nuclear - synthesis, understanding the structure of astrophysical compact-objects such as neutron stars and predicting regions of enhanced stability in the super heavy elements. The FNPMLS project will develop ultra-sensitive methodologies that set a new - paradigm in laser spectroscopy. It builds on the cutting edge technology of collinear resonance ionization spectroscopy (CRIS) that I have developed during my STFC Advanced Fellowship. The CRIS technique combines the high resolution nature of - collinear laser spectroscopy with the high sensitivity of resonance ionization spectroscopy. The research programme and investment outlined in this proposal will place my team in a unique and world leading position. This work will happen in advance - of the next generation of radioactive beam facility such as SPIRAL2, FAIR and FRIB and will provide the essential ingredients for future fundamental questions. - - 2020-03-31, ongoing project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - FNPMLS - - - ERC-2014-CoG - - - 648381 - - - - - THE UNIVERSITY OF MANCHESTER - - - EUR 183 454,80 - - - Sources and sinks for excess Xe and Ar on the Moon - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Noble gases trace the evolution of reservoirs inside terrestrial planetary bodies because their isotopic signatures are diagnostic of volatile sources. In addition, original compositions can be modified by radioactive decay of - rock forming elements, providing constraints on the chemistry of an interior reservoir and the time at which it was isolated (since when noble gases were retained). Some lunar samples are known to preserve signatures in xenon and argon that were - degassed from one or more interior sources to the exosphere, then incorporated into the regolith, potentially allowing this record to be read. In this work I will combine (i) my expertise in lunar evolution, sample characterization and the 40Ar-39Ar - system, (ii) the University of Manchester’s expertise in xenon isotope systematics, world-leading instrumentation for xenon isotopic analysis and state-of-the-art sample characterisation facilities, and (iii) expertise relevant to the lunar exosphere - from a network of collaborators. With this team, I will (i) determine the range of xenon and argon signatures in lunar regolith samples and the times at which they were incorporated, (ii) develop a model of the lunar exosphere to infer source - reservoir compositions from those measured in samples and so (iii) investigate the number of contributing lunar reservoirs, their compositions and their histories. The results of this interdisciplinary study will be disseminated to the range of - specialist and non-specialist audiences. They will serve to test models of lunar evolution, allow comparison with the Earth and Mars to gain wider understanding of terrestrial planetary bodies, and stimulate engagement with planetary science. - Additionally, I will develop my leadership and teaching skills by completing the University of Manchester’s New Academics Programme, equipping me to move to the next stage of my career as a researcher, leader and teacher for the next generation of - multidisciplinary planetary scientists. - - 2020-04-30, Grant Agreement signed - - - 2018-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - XeMoon - - - H2020-MSCA-IF-2016 - - - 749815 - - - - - THE UNIVERSITY OF MANCHESTER - THE UNIVERSITY OF MANCHESTER - - - EUR 1 922 451 - - - Nucleation of Organic Crystals onto 2D materials - - - EUR 1 922 451 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The formation of crystalline solids from liquid-phase precursor is a central idea in materials chemistry. Organic crystal structures can be found in a large number of products, including food, explosives, pigments and - pharmaceuticals. Control of molecular assembly is therefore a fundamental problem for both research and industry and it involves substantial scientific and economic challenges. For example, polymorphism is crucial for drug manufacturers because the - crystal structure, morphology and size, can all affect the stability, efficacy and production cost of the drug. Therefore, it is essential to achieve a deep understanding on the molecular processes happening at the early stage of crystallization. - Although important results have been obtained, our understanding on how a crystal of organic molecules nucleates on a surface is still poor. To go beyond state-of-the art we need techniques able to probe rare nucleation events with nanoscale - resolution and very high sensitivity, providing direct insights on the structure of the nuclei and their interaction with the environment. - - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - NOC2D - - - ERC-2014-CoG - - - 648417 - - - - - CONSIGLIO NAZIONALE DELLE RICERCHE - - - EUR 180 277,20 - - - Smart Metal Organic Frameworks for Sensing Volatile Organic Compounds - - - EUR 180 277,20 - - - Italy - - - Research Organisations - - SmartMOFs targets a new generation of Metal Organic Frameworks (MOFs) for sensing harmful volatile organic compounds (VOCs). The innovation of SmartMOFs is based on a combined sensing approach, where both optical and - electrical changes in the MOF material enable the recognition event. The primary step to meet the required combination of specific absorption/emission and conductivity properties is the selection of the MOF structural units, supported by theoretical - investigations. The selected units will offer extensive connectivity, flexibility, tunable porosity and functionalization of the inner surface of the network, with groups interacting with the analytes by means of coordination bonds, p-p interactions - or hydrogen bonds. Harmful volatile compounds will entail gases and solvents (e.g., alcohols, benzene, hexane, cyclohexane). The SmarMOFs sensors will show increased selectivity and sensitivity with respect to the state-of-the-art. Deposition of the - new MOF materials on surfaces to create sensor devices will be accomplished by advanced deposition techniques. SmartMOFs will thus overtake the current bottleneck of processability that limits practical applications of these materials, filling the - gap between basic research and marketable applications. The high interdisciplinarity of SmartMOFs and its foreseen applications in the highly relevant area of public health will be a springboard for the Experienced Researcher to start a successful - career in the academic or industrial sectors. - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - SmartMOFs - - - H2020-MSCA-IF-2016 - - - 751175 - - - - - THE UNIVERSITY OF MANCHESTER - - - EUR 183 454,80 - - - Organometallic Single-Molecule Magnets - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - In this project, we will develop new single-molecule magnets (SMMs) that combine the strong magnetic anisotropy of lanthanide ions with a series of novel radical ligands. Highly unusual di- and tri-metallic Ln-SMMs are - proposed in which the metals are bridged by radicals with heavy Group 15 donor atoms (i.e. the pnictogens, phosphorus-bismuth). The SMM field is dominated by systems with diamagnetic ligands: our radical ligands are novel, hence their applications in - single-molecule magnetism will be unprecedented. We will exploit the rich electrochemistry of the proposed ligands: our DFT calculations show that the target heavy pnictogen radical anions have huge spin densities on the donor atoms, hence the - diffuse unpaired spin of the radicals will provide a way of switching off the quantum tunnelling mechanisms that otherwise prevent hysteresis. Ultimately, this project introduces the potential for creating SMMs that show hysteresis at unprecedentedly - high temperatures. - - 2017-09-30, closed project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - OrganoMag - - - H2020-MSCA-IF-2014 - - - 653784 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 495 500 - - - Control of contact interactions for robots acting in the world - - - EUR 1 495 500 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - What are the algorithmic principles that would allow a robot to run through a rocky terrain, lift a couch while reaching for an object that rolled under it or manipulate a screwdriver while balancing on top of a ladder? - Answering this seemingly naïve question resorts to understanding the fundamental principles for robot locomotion and manipulation, which is very challenging. However, it is a necessary step towards ubiquitous robots capable of helping humans in an - uncountable number of tasks. The fundamental aspect of both locomotion and manipulation is that the dynamic interaction of the robot with its environment through the creation of physical contacts is at the heart of the tasks. The planning of such - interactions in a general manner is an unsolved problem. Moreover, it is not clear how sensory information (e.g. tactile and force sensors) can be included to improve the robustness of robot behaviors. Most of the time, it is simply discarded. - CONT-ACT has the ambition to develop a consistent theoretical framework for motion generation and control where contact interaction is at the core of the approach and an efficient use of sensory information drives the development of high performance, - adaptive and robust planning and control methods. CONT-ACT develops an architecture based on real-time predictive controllers that fully exploit contact interactions. In addition, the structure of sensory information during contact interactions is - experimentally analyzed to create sensor representations adapted for control. It is then possible to learn predictive models in sensor space that are used to create very reactive controllers. The robot constantly improves its performance as it learns - better sensory models. It is a step towards a general theory for robot movement that can be used to control any robot with legs and arms for both manipulation and locomotion tasks and that allows robots to constantly improve their performances as - they experience the world. - - 2020-05-31, ongoing project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - CONT-ACT - - - ERC-2014-STG - - - 637935 - - - - - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - UNIVERSITAETSMEDIZIN GOETTINGEN - GEORG-AUGUST-UNIVERSITAET GOETTINGEN - STIFTUNG OEFFENTLICHEN RECHTS - - - EUR 159 460,80 - - - Neurophysiological Biomarkers of Cortical Plasticity Induced by Neuromodulation - - - EUR 159 461,38 - - - United Kingdom - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - One of the major issues when dealing with therapies for the rehabilitation of the lower limbs in stroke survivors is the in-deep assessment of their effectiveness and the lack of biomarkers for motor recovery. The motor - functionality after therapy is evaluated only through clinical tests and scales which do not give information on the effective muscle state and the changes at the corticospinal level. The aim of restoring the motor functions has moved much of the - attention of clinicians and researcher towards the use of the combination of brain stimulation techniques for the assessment of cortical excitability and Brain-Computer Interfaces (BCI) for the control of rehabilitation devices. This intervention - induces cortical plasticity and reactivates the closed-loop pathway between the impaired cortical tract and the limb by using the cortical command to drive the device for the generation of the afferent volley. However, nothing is known about the - changes of the neurophysiological correlates and how these influence the effective recovery of motor functions. NeuroN represents the first systematic attempt to investigate the neurophysiological correlates of changes in the excitability of the - cortical areas responsible for ankle dorsiflexion in chronic hemiparetic stroke survivors with drop foot impairment and to identify novel biomarkers of motor recovery. NeuroN aims at filling the gap of knowledge on the functional effects of increased - plasticity in chronic stroke survivors by integrating a BCI robot-based platform with the high-density surface electromyographic (HD-sEMG) recordings. The information coming from the decomposition of HD-sEMG signals give insight into the behavior of - the motoneurons in the spinal cord and on the effective control command. NeuroN is expected to address one of the most intriguing issues in the neurorehabilitation field: the novel biomarkers developed will help in shaping new therapies for the - recovery of motor function of stroke patients. - - 2017-08-31, closed project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - NeuroN - - - H2020-MSCA-IF-2014 - - - 660905 - - - - - UNIVERSITA DEGLI STUDI DI PADOVA - UNIVERSITA DEGLI STUDI DI PADOVA - TECHNISCHE UNIVERSITEIT DELFT - - - EUR 1 999 985 - - - A seamless multi-scale model for contact, friction, and solid lubrication - - - EUR 1 999 985 - - - Italy - Italy - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Friction and wear are liable for enormous losses in terms of energy and resources in modern society. Costs related to unwanted friction in industrialised countries are estimated to be about 3% of the gross domestic product. - Urgency is even greater nowadays as friction between micro-components has become the bottleneck of several applications for which miniaturisation is critical. - - 2021-05-31, ongoing project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Italy - - - FricLess - - - ERC-2015-CoG - - - 681813 - - - - - BILKENT UNIVERSITESI VAKIF - BILKENT UNIVERSITESI VAKIF - - - EUR 1 276 640 - - - Theory and Empirics of Asymmetry - - - EUR 1 276 640 - - - Turkey - Turkey - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Why is there a Volcker disinflation but no Bernanke re-inflation? It is not only because of the zero lower bound as a nascent literature is suggesting that monetary policy is more potent in a contractionary stance than in an - expansionary stance away from the ZLB as well. But why? Why is it that central banks cut interest rates much faster than they raise them? Why does it seem like financial markets give much different responses to seemingly similar macroeconomic news at - different times? Are these all related? - - - 2022-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Turkey - - - TEA - - - ERC-2016-COG - - - 726400 - - - - - THE UNIVERSITY OF MANCHESTER - - - EUR 195 454,80 - - - Borylated Conjugated Materials - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Recent work at the University of Manchester has developed an efficient synthetic method for transition metal free electrophilic borylation of aromatics and heteroaromatics. This approach has recently been extended to the - fusion of conjugated materials containing the acceptor moiety benzothiadiazole – a group that is ubiquitous in materials for organic electronics. This functionalization leads to a significant increase in the electron affinity of the materials and a - considerable reduction in the band gap, consistent with near-IR emission in organic light emitting diodes (OLEDs), ambipolar organic field effect transistor (OFET) mobility, improved n-type stability and effective light harvesting in organic - photovoltaic cells (OPVs). The BORCOM project will use this methodology to deliver novel molecules and polymers that exhibit high electron affinities and small band gaps by functionalization of azole or azine containing acceptors in the conjugated - backbone. The performance of the new materials as n-type semiconductors in OFETs, light harvesting and electron acceptors in OPVs and dopants/emitters in OLEDs will be evaluated. - - 2017-06-30, closed project | - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - BORCOM - - - H2020-MSCA-IF-2014 - - - 660149 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 3 146 598 - - - Cryogenic Rare-event Observatory with Surface Sensitivity - - - EUR 3 146 598 - - - France - France - - - Research Organisations - Research Organisations - - CROSS will set the grounds for large-scale experiments searching for neutrinoless double beta decay with zero background at an exposure scale of ~1 tonne x year and with very high energy resolution – about 1.5‰ – in the region - of interest. These features will enable searching for lepton number violation with unprecedented sensitivity, penetrating in prospect the direct-ordering region of the neutrino masses. CROSS will be based on arrays of TeO2 and Li2MoO4 bolometers - enriched in the isotopes of interest 130Te and 100Mo, respectively. There are strong arguments in favor of these choices, such as the high double beta transition energy of these candidates, the easy crystallization processes of TeO2 and Li2MoO4, and - the superior bolometric performance of these compounds in terms of energy resolution and intrinsic purity. The key idea in CROSS is to reject surface events (a dominant background source) by pulse-shape discrimination, obtained by exploiting - solid-state-physics phenomena in superconductors. The surfaces of the crystals will be coated by an ultrapure superconductive aluminium film, which will act as a pulse-shape modifier by delaying the pulse development in case of shallow energy - depositions, exploiting the long quasi-particle life-time in aluminium. This method will allow getting rid of the light detectors used up to now to discriminate surface alpha particles, simplifying a lot the bolometric structure and achieving the - additional advantage to reject also beta surface events, which unfortunately persist as an ultimate background source if only alpha particles are tagged. The intrinsic modularity and the simplicity of the read-out will make CROSS easily expandable. - The CROSS program is focused on an intermediate experiment with 90 crystals, installed underground in the Canfranc laboratory, which will be not only extremely competitive in the international context but also a decisive step to demonstrate the - enormous potential of CROSS in terms of background. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - France - - - CROSS - - - ERC-2016-ADG - - - 742345 - - - - - THE UNIVERSITY OF MANCHESTER - - - EUR 195 454,80 - - - Multi-modal optical imaging platform for Biology - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - With the progress of biological investigation, there comes a strong wish or need for imaging biological samples with multi-modality and on different scales. To meet this need, this project will develop a multi-modal 3D optical - imaging platform that images on the multi-scale, from tissues to molecules, by integrating optical coherence tomography (OCT), stimulated emission depletion microscopy (STED), and fluorescence correlation spectroscopy (FCS). Incorporation of - structured illumination, adaptive optics and focused engineering will improve spatial resolution, imaging depth, and molecular concentration sensitivity. The investigated technique will be tested and applied to biology investigation, including but - not limited to, tissue and cell recovery in the Zebrafish (as a model organism) after laser damage. The multi-scale structural and functional image, as well as the dynamics on the protein level provided by this investigation, will potentially reveal - tissue and cell recovery mechanisms, and in the long run contribute to the cure of disease along with understanding the mechanisms of tissue damage. This project will advance the state-of-the-art in optical imaging, and create new links between basic - research and biological and clinical applications. - - 2018-12-31, Grant Agreement terminated - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - MOIPB - - - H2020-MSCA-IF-2015 - - - 699718 - - - - - THE UNIVERSITY OF BIRMINGHAM - ASSOCIATION DES AMIS DE LA MEDECINE SOCIALE - INSTITUT NATIONAL POLYTECHNIQUE DE TOULOUSE - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSITE PAUL SABATIER TOULOUSE III - - - EUR 193 500 - - - Next generation of 3D multifunctional materials and coatings for biomedical applications - - - EUR 274 500 - - - United Kingdom - France - France - France - France - - - Higher or Secondary Education Establishments - Other - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - - NEXT-3D is an innovative European-Australian project that consists of 4 academic and 2 non-academic members. The research methodology is based on the multi-disciplinary and inter-sectorial collaboration among the network - participants and focuses into main themes: 3D Printing, Enhance Coating, and medical translation with the main aim to develop the next generation of multifunctional 3D materials for orthopaedic and dental implants. Multifunctional materials with drug - delivery properties and antibacterial properties are desirable by clinicians. These materials promote healing and can reduce and prevent from unexpected effects on patients. Research will be conducted following a multi- and inter-disciplinary - research methodology designed to develop innovative biomedical materials using advanced processing technologies (3D laser printing and sintering) with market potential. The proposed research and innovative programme will lead to the advancement of - knowledge in the field and to new materials with superior properties. - - 2018-05-31, ongoing project | - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - United Kingdom - - - NEXT-3D - - - H2020-MSCA-RISE-2014 - - - 645749 - - - - - UNIVERSIDAD POMPEU FABRA - UNIVERSIDAD POMPEU FABRA - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 1 888 033 - - - Information Theory with uncertain laws - - - EUR 1 888 033 - - - Spain - Spain - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Shannon's Information Theory paved the way for the information era by providing the mathematical foundations of digital information systems. A key underlying assumption of Shannon's key results is that the probability law that - governing system is known, allowing to optimize the codebook and decoder accordingly. - - - 2022-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Spain - - - ITUL - - - ERC-2016-COG - - - 725411 - - - - - Eidgenössische Technische Hochschule Zürich - Eidgenössische Technische Hochschule Zürich - - - EUR 2 500 000 - - - Soft Micro Robotics - - - EUR 2 500 000 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The field of Micro and Nano Robotics has made impressive strides over the past decade as researchers have created a variety of small devices capable of locomotion within liquid environments. Robust fabrication techniques have - been developed, some devices have been functionalized for potential applications, and therapies are being actively considered. While excitement remains high for this field, we are facing a number of significant challenges that must be addressed - head-on if continued progress towards clinical relevance is to be made. This project will address what we consider to be primary roadblocks to be overcome. This includes the development of bioerodable and non-cytotoxic microrobots, development of - autonomous devices capable of self-directed targeting, catheter-based delivery of microrobots near the target, tracking and control of swarms of devices in vivo, and the pursuit of clinically relevant therapies. - - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Switzerland - - - SOMBOT - - - ERC-2016-ADG - - - 743217 - - - - - KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW - - - EUR 177 598,80 - - - Longitudinal employer–employee perspectives on the role of human capital investments for retirement transitions - - - EUR 177 598,80 - - - Netherlands - - - Research Organisations - - European and national ageing policies give high priority to increasing retirement age and employability of older people, but no effective solution exists. The project aims to provide practical recommendations based on evidence - on the role of human capital investments (at individual and company level) for retirement transitions. This is still an understudied area in ageing research. It is also neglected by policy-makers who miss the fact that employees must be willing and - able to work longer, and employers must be willing and able to provide adequate opportunities for extended employment. - - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - LEEP - - - H2020-MSCA-IF-2016 - - - 748671 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 195 454,80 - - - Soft Chemical Control of the Physical Properties of Layered Solids - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - This research programme is fundamental solid state chemistry at the boundary with condensed matter physics. It will discover new transition metal compounds with layered crystal structures and aims to put them on the world - stage by exploiting the compositional tunability which is intrinsic to non-molecular systems. The discovery and chemical rationalisation of new composition-structure-property relationships is anticipated to lead eventually to future industrial - developments in applications as wide ranging as superconductors, thermoelectric materials, magnetic materials, batteries and heterogeneous catalysis. Parallel to the research, the fellow’s outreach activities will centre on highlighting these - “synthetic minerals” to the general public in a permanent exhibit. The host group and the fellow bring complementary expertise to the project and the career development of the fellow will be through the research and outreach and also in the - development of collaborations with Oxford Physics, and the world-leading international facilities for neutron and synchrotron X-ray science at the local Harwell campus and in Grenoble. - - 2018-07-25, Grant Agreement terminated - - - 2016-07-26 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SOLLAY - - - H2020-MSCA-IF-2014 - - - 658832 - - - - - LUNDS UNIVERSITET - LUNDS UNIVERSITET - - - EUR 2 000 000 - - - Uncovering targets for ex vivo expansion of hematopoietic stem cells to enhance cell therapies of blood disorders - - - EUR 2 000 000 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Mechanisms of self-renewal in hematopoietic stem cells (HSCs) have been subject to intense studies during the last decades. However, this is still a poorly defined process and very limited progress has been made in the long - sought goal of expanding HSCs ex vivo to allow for critical improvements of bone marrow transplantation procedures for cancer patients and potentially a broader use of HSCs in gene therapy and regenerative medicine. The aim of this research program - is to systematically identify and characterize regulators of self-renewal in human HSCs and to develop strategies for stem cell expansion. Within the project we will develop novel paradigms for CRISPR (clustered regularly interspaced short - palindromic repeats) mediated gene editing in primary human HSCs to enable detailed assessment of gene function. We will further employ forward genetic screening approaches based on both CRISPR/Cas9 gene editing and RNA interference (RNAi) gene - silencing to identify regulators of renewal and differentiation in human HSCs. Large numbers of HSCs will be targeted with genome-wide lentiviral CRISPR (sgRNA) and short hairpin RNA (shRNA) libraries. Screening assays for HSC self-renewal will be - evaluated in a pooled format and de-convoluted using next generation sequencing, allowing thousands of perturbations to be assayed in parallel. Candidate genes from the screens will be studied further using genetic barcoding and transplantations - assays in immundeficient mice to test whether they can be targeted to induce expansion of HSCs ex vivo. Finally, based on our findings, we aim to develop GMP compatible conditions for HSC expansion in preparation for clinical trials involving - expansion of umbilical cord blood derived stem cells to treat patients with acute leukemia. - - 2020-07-31, ongoing project - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Sweden - - - UNEXPECTED - - - ERC-2014-CoG - - - 648894 - - - - - ROYAL COLLEGE OF SURGEONS IN IRELAND - UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN - - - EUR 175 866 - - - Local delivery of PTH(1-34) from an injectable collagen-hydroxyapatite scaffold for non-invasive treatment of bisphosphonate associated atypical femoral fractures - - - EUR 175 866 - - - Ireland - Ireland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Having recently returned to the EU following Postdoctoral training in Australia, I hope to work as a MSCA Reintegration Fellow to tackle a devastating clinical orthopaedic challenge for which there is currently no effective - treatment. Specifically, bisphosphonate (BP) associated atypical femoral fractures (AFFs) in osteoporotic patients which are associated with excruciating pain and high levels of morbidity and mortality. The scientific goal of this proposal is to - integrate my tools in bone tissue engineering with the advanced drug delivery expertise of Prof. David Brayden’s group at University College Dublin (UCD) to develop a novel injectable therapeutic scaffold as a non-invasive treatment for AFFs. This - proposal outlines an innovative research project that aims to implement a revolutionary strategy utilising Teriparatide (PTH-(1-34)) to target BP remobilisation away from AFF site and induce bone repair. In addition, a tissue engineering strategy - will be employed that combines a regenerative, load bearing biomaterial for controlled local delivery of PTH(1-34) as a pioneering advance for AFF treatment. As a newly appointed academic, the training objective of this grant is to attain the - requisite scientific and complementary skills to successfully develop an independent research programme. This will be achieved through the expert supervision and input of Prof. Brayden and backed up by colleagues in the lab and UCD staff training - activities. In addition, by managing the project, I will further develop skills relating to planning and reporting, financial management, dissemination, patent filing and commercialisation. I will also avail of opportunities to recruit and supervise - students on this project or related works. In summary, this grant will provide invaluable help to establish an independent research niche in active and emerging research fields, while equipping me with the skills needed as a newly appointed lecturer - embarking on an independent research career. - - 2018-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Ireland - - - InjectCHA - - - H2020-MSCA-IF-2015 - - - 705994 - - - - - NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU - INSTITUTO SUPERIOR TECNICO - UNIVERSIDADE DO PORTO - LINKOPINGS UNIVERSITET - UNIVERSIDAD DE SEVILLA - MARITIME ROBOTICS AS - NORUT NORTHERN RESEARCH INSTITUTE AS - FUNDACION ANDALUZA PARA EL DESARROLLO AEROESPACIAL - HONEYWELL INTERNATIONAL SRO - INNOVATIONSGESELLSCHAFT TECHNISCHE UNIVERSITAT BRAUNSCHWEIG MBH - - - EUR 3 851 102,88 - - - Autonomous Unmanned Aerial Systems for Marine and Coastal Monitoring - - - EUR 3 851 103,31 - - - Norway - Portugal - Portugal - Sweden - Spain - Norway - Norway - Spain - Czech Republic - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - European countries have vast coasts and economic zones that go far into the Atlantic and Arctic oceans and are challenging to monitor and manage. The need to protect and manage the vulnerable natural environment and marine - resources in a sustainable manner is an important policy that is manifested in European legislation such as the European Strategy for Marine and Maritime Research. Moreover, the drive towards activities in more remote locations and harsher - environment demands new approaches and technologies. A key technology is the increased use of autonomous unmanned aerial vehicle systems (UAS) instead of manned aircraft, buoys, ships or satellite-based remote sensing. UAS offers potential advantages - such as high endurance, reduced cost, increased flexibility and availability, rapid deployment, higher accuracy or resolution, and reduced risk for humans and negative impact on the environment. - - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Norway - - - MarineUAS - - - H2020-MSCA-ITN-2014 - - - 642153 - - - - - HERIOT-WATT UNIVERSITY - HERIOT-WATT UNIVERSITY - UNIVERSITY OF DUNDEE - - - EUR 1 999 407 - - - Real-TIME probing of Ultrafast Phenomena - - - EUR 1 999 407 - - - United Kingdom - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The perception of the world surrounding us depends on how we illuminate and capture it. For example, our direct observation of high-speed phenomena is limited by the speed of the human visual system. A well known method to - visualize fast events is to capture them at very high frame rates with high-speed cameras, and then play the movie in slow-motion, enabling us to understand what happens at short timescales. - - - 2020-06-30, ongoing project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - UPTIME - - - ERC-2014-STG - - - 640537 - - - - - STICHTING VU - THE UNIVERSITY OF NOTTINGHAM - UNIVERSITY OF GLASGOW - BAYERISCHE JULIUS-MAXIMILIANS UNIVERSITAT WURZBURG - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - UNIVERSIDAD AUTONOMA DE MADRID - ARGEN-X - GRIFFIN DISCOVERIES BV - - - EUR 3 893 983,56 - - - ONCOgenic Receptor Network of Excellence and Training - - - EUR 3 893 983,56 - - - Netherlands - United Kingdom - United Kingdom - Germany - France - Germany - France - Spain - Belgium - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Cancer is a leading health concern. There is a need to fully understand the fundamental processes underlying development of cancer. There is increasing evidence that G protein-coupled receptors (GPCRs) and their associated - signalling cascades are involved in both cancer progression and metastasis. As oncogenic GPCRs are likely to be amenable to manipulation via drugs they are ideal therapeutic targets. In ONCORNET (Oncogenic Receptor Network of Excellence and Training) - we propose to target two oncogenic GPCRs; the chemokine receptors CXCR4 and CXCR7. These are highly expressed in a range of tumours and yet their role in cancer progression is not well understood. We will focus on unravelling how CXCR4 and CXCR7 are - or can be modulated (small molecules, pepducins, nanodies) and investigate the effects on oncogenic responses. This represents crucial knowledge that we currently do not have and yet may well provide potential leads for drug development and - commercialisation. ONCORNET will bring together the leading research scientists and labs in Europe with an interest in GPCRs and 15 early stage researchers. We will employ all the latest multidisciplinary research technologies to understand the role - of these GPCRs in cancer and develop CXCR4 and CXCR7 tools for diagnostic and therapeutic purposes. Importantly, developed approaches can be extrapolated to other oncogenic GPCRs. The ONCORNET consortium will offer an extensive multidisciplinary - training programme to the ESRs to ensure that they can operate in today’s drug discovery programmes. This will include both research (e.g. drug discovery, proteomics, imaging, modelling) and transferable (e.g. entrepreneurship, writing, media - training) skill sets –that is rarely offered at PhD level. We will train ESRs to develop the next generation of multidisciplinary scientists with skills that are highly demanded by many of today’s employers in drug development industries. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Netherlands - - - ONCORNET - - - H2020-MSCA-ITN-2014 - - - 641833 - - - - - MONTANUNIVERSITAT LEOBEN - STIFTELSEN SINTEF - Eidgenössische Technische Hochschule Zürich - HBI HAERTER GMBH - BAYERISCHES LASERZENTRUM - GENERAL ELECTRIC (SWITZERLAND) GMBH - ACONDICIONAMIENTO TARRASENSE ASSOCIACION - - - EUR 939 137,50 - - - Design Study for the European Underground Research Infra-structure related to Advanced Adiabatic Compressed Air Energy Storage - - - EUR 1 373 637,50 - - - Austria - Norway - Switzerland - Germany - Germany - Switzerland - Spain - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - - Challenges like climate change, economic, social and sustainable development as well as security are closely linked to the energy supply of European societies. In 2009, the European Union adopted a ‘climate and energy package’ - including that at least 20% of EU gross final energy consumption have to come from renewable energy sources until 2020. The challenge of RICAS2020 is given by intermittent renewable energy sources which require increased energy storage to time shift - this energy to meet daily demand. As a consequence, the demand for technologies for providing and storing energy is consequently increasing. - - - 2018-05-31, ongoing project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-1-2014 - Design studies - - - CSA - Coordination and support action - - - Austria - - - RICAS2020 - - - H2020-INFRADEV-1-2014-1 - - - 654387 - - - - - ACADEMISCH ZIEKENHUIS GRONINGEN - OTTO-VON-GUERICKE-UNIVERSITAET MAGDEBURG - UNIVERSITY OF YORK - H. Lundbeck A/S - Fondazione Stella Maris - UNIVERSITEIT UTRECHT - HADASSAH MEDICAL ORGANIZATION - PATTERN RECOGNITION COMPANY GMBH - BRAIN INNOVATION BV - WHITEMATTER LABS GMBH - - - EUR 3 886 818,12 - - - Training the Next Generation of European Visual Neuroscientistsfor the benefit of innovation in health care and high-tech industry - - - EUR 3 886 818,12 - - - Netherlands - Germany - United Kingdom - Denmark - Italy - Netherlands - Israel - Germany - Netherlands - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The human visual brain can learn and adapt to change, which solves many of the problems posed by an ever-changing visual environment. However, to maintain a consistent overall representation of the visual world, the brain also - has to retain previously acquired neuronal mechanisms. The key is to strike a balance between plasticity and stability. - - 2019-02-28, ongoing project | - - - 2015-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Netherlands - - - NextGenVis - - - H2020-MSCA-ITN-2014 - - - 641805 - - - - - UNIVERSIDAD AUTONOMA DE MADRID - UNIVERSIDAD AUTONOMA DE MADRID - - - EUR 1 704 375 - - - Using extreme magnetic field microscopy to visualize correlated electron materials - - - EUR 1 704 375 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Strong electronic correlations often produce intertwined phases where multiple length scales coexist. These produce spatially varying electronic properties containing unique insight on the many-body effects that determine the - emergence of novel collective behavior. Addressing the problem of electron correlations requires powerful microscopes probing electronic properties down to atomic scale. - - 2021-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Spain - - - PNICTEYES - - - ERC-2015-STG - - - 679080 - - - - - UNIVERSIDAD AUTONOMA DE MADRID - - - EUR 170 121,60 - - - Changing the course of cognitive decline in normal aging with positive emotions by training brain plasticity - - - EUR 170 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - Aging is a primary health concern for all European countries and the entire world. Healthy adults experience memory declines that affect daily functioning, yet their ability to process emotion is well-preserved. The benefit of - utilizing older adults spared emotional abilities to help mitigate memory declines has not been previously explored and will have substantial implications for daily life. The current project has two main goals. First, we will employ cutting-edge - functional imaging technology to investigate age-related neural interactions between emotion and memory. To this end, electroencephalography (EEG) will record electrical brain activity non-invasively while participants perform an innovative memory - task with an emotional component. Second, we will implement an innovative memory training programme to test brain plasticity, with a focus on transferring these benefits to daily life. It will enhance the importance of age-related preserved emotions - to improve memory deficits. EEG activity will be recorded before and after training to examine the neural changes as a result of training. Besides the extensive research experience of the applicant in fundamental research of aging, the novel approach - will be to conduct this project by synergizing key aspects of fundamental and applied sciences, emphasizing transfer of knowledge and collaboration with industry. There is a clear benefit of the mobility for both the applicant and the host, ensuring - high quality results and dissemination. In this regard, the host will ensure the acquisition of new technical, management, tutorial and transferable skills. The applicant will also benefit from a multidisciplinary environment enhancing international - collaboration that will surely contribute to diversify her career. Finally, via a specialized Career Development Plan, the host will provide the ideal training and validation environment, through which the applicant will reach unprecedented levels of - professional maturity - - 2018-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - MEMOTION - - - H2020-MSCA-IF-2014 - - - 660031 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 170 121,60 - - - Ostreid herpesvirus 1: Genetic selection of Resistant strains and environmental interaction in the Atlantic coast of Spain (Galicia) - - - EUR 170 121,60 - - - Spain - - - Research Organisations - - One of the main concerns in the aquaculture sector is the significant mortality of the Pacific oyster, Crassostrea gigas, the principal shellfish cultivated worldwide. Among other factors, the presence of a virus has been - directly associated with these mortality events which can largely exceed normal losses. The economic impact of the disease in oyster production has reached worrying levels since it has been spread to important producer countries in both hemispheres. - - - 2017-08-31, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - ResisGal - - - H2020-MSCA-IF-2014 - - - 659072 - - - - - UNIVERSITE PARIS III SORBONNE NOUVELLE - - - EUR 173 076 - - - Rethinking Work: Intellectual Responses to the 2008 Financial Crisis in French Film and Media - - - EUR 173 076 - - - France - - - Higher or Secondary Education Establishments - - Social critics have observed how, since the 1970s, many forms of work have become increasingly redundant due to technological advances. At the same time, Europe has witnessed economic crises, financialization, growing - inequality and debt, yet also responses to these phenomena in, for example, movements advocating debt relief and a citizens’ basic income. These issues have become particularly acute in the wake of the 2008 financial crisis. In France since the - crisis there has been an increase in rhetoric surrounding the notion of work as well as many films engaging with this issue. - - 2018-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - WORKRETHINK - - - H2020-MSCA-IF-2015 - - - 708042 - - - - - UNIVERSIDAD DE SEVILLA - - - EUR 170 121,60 - - - Bond Activation and Catalysis by Transition Metal Frustrated Lewis Pairs - - - EUR 170 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - Catalysis is critical to the delivery of future growth in the manufacturing sector: ca. 75% of all chemicals currently require catalysts at some stage in their manufacture, with catalytic processes generating €1,000 Bn in - products world-wide. This proposal targets a step-change in homogenous catalysis by approaching it from a new perspective. Frustrated Lewis Pairs (FLPs) are among the most promising new avenues for the development of future catalysts and offer - important advantages in the context of sustainability. Thus the young field of FLP chemistry has experienced an enormous expansion since its founding discoveries one decade ago. However, this rapid development contrasts with the very limited number - of examples in the literature in which one of the Lewis acid/base (LA/B) components is based on a transition metal. The current proposal aims to combine the rich chemistry of transition metals (ultimately Earth-abundant elements) with the powerful - reactivity offered by FLP systems by substituting one of its LA/B components by a transition metal. The extraordinary structural diversity of transition metals, along with the rich variety of elementary reactions that take place over those centres, - are attributes that will extend the usefulness of FLPs far beyond the present (mainly) hydrogenation reactions and should allow developing new catalytic processes unreachable for current homogeneous catalysts. The possibilities are as unexplored as - unlimited. We aim to exploit Pt and Au systems, for which preliminary results are available in the host group and will give high confidence of short-term success. Subsequently we will build on the key principles so established to expand our approach - to ecologically more benign first-row transition metals. The potential in bond activation and catalysis of the resulting transition metal FLP systems will be explored with the ultimate goal of developing novel catalytic cycles of industrial - relevance. - - 2018-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - TM-FLPS - - - H2020-MSCA-IF-2015 - - - 706008 - - - - - SCHOOL OF ORIENTAL AND AFRICAN STUDIES, UNIVERSITY OF LONDON - SCHOOL OF ORIENTAL AND AFRICAN STUDIES, UNIVERSITY OF LONDON - UNIVERSITAT TRIER - THE UNIVERSITY OF BIRMINGHAM - FREIE UNIVERSITAET BERLIN - - - EUR 2 499 618 - - - The Multimedia Yasna - - - EUR 2 499 618 - - - United Kingdom - United Kingdom - Germany - United Kingdom - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - What exactly are the words which priests recite in the Yasna, the core ritual of one of the most ancient and influential living religions, Zoroastrianism? What is their meaning and how do they relate to the ritual actions? The - Yasna is significant for our cultural heritage not only because of its influential thought system which arguably impacted on post-exilic Judaism, nascent Christianity and Islam, but also because with parts of it going back to the 2nd millennium BCE, - it is the oldest witness to Iranian languages. Its full appreciation, however, is severely hampered by the presence of outdated editions and translations or by their absence altogether. Moreover, the relationship between the text recited and the - action performed during the ritual is unexplored due to a lack of documentary evidence. The Multimedia Yasna proposes to fill these gaps in a methodologically ground-breaking fashion. - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - MUYA - - - ERC-2015-AdG - - - 694612 - - - - - UNIVERSITEIT MAASTRICHT - UNIVERSITEIT MAASTRICHT - - - EUR 1 799 034,44 - - - Migrant Life Course and Legal Status Transition - - - EUR 1 799 034,44 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - When does citizenship provide a boost to migrant integration? A fast-track to citizenship can maximise the potential for settlement success, though too short a pathway can disincentivise integration. Not all migrants have an - equal interest in naturalising and some are discouraged by restrictive policies. Yet little is known about why, how and for whom legal status transition matters and, especially, how policy variation impacts on this relation. Which migrants are most - discouraged by stricter requirements for naturalisation? For whom carries citizenship the largest pay-off? Does it still matter if a migrant acquires citizenship after a long waiting period? This project combines for the first time the ideas that a) - migrants have different motivations to naturalise; b) legal status transitions are conditioned by the institutional and socioeconomic contexts in origin and destination countries and c) the potential ‘integration premium’ associated with - naturalisation is conditioned by the trajectory into citizenship. - - - 2021-07-31, ongoing project - - - 2016-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - MiLifeStatus - - - ERC-2015-CoG - - - 682626 - - - - - UNIVERSIDAD DE SEVILLA - UNIVERSIDAD DE SEVILLA - - - EUR 2 843 750 - - - Molecular mechanisms of acute oxygen sensing. - - - EUR 2 843 750 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Oxygen (O2) is essential for life on Earth. This proposal deals with the study of the molecular mechanisms underlying acute O2 sensing by cells, a long-standing issue that is yet to be elucidated. In recent years, the - discovery of hypoxia inducible transcription factors and their regulation by the O2-dependent hydroxylases has provided a solid framework for understanding genetic responses to sustained (chronic) hypoxia. However the mechanisms of acute O2 sensing, - necessary for the activation of rapid, life-saving, compensatory respiratory and cardiovascular reflexes (e.g. hyperventilation and sympathetic activation), are unknown. While the primary goal of the project is to characterize the molecular - mechanisms underlying acute O2 sensing by arterial chemoreceptors (carotid body –CB- and adrenal medulla –AM-), we will also extend our study to other organs (e.g. pulmonary and systemic arteries) of the homeostatic acute O2-sensing system. We will - investigate the role of mitochondria, in particular complex I (MCI), in acute O2 sensing. Previous data from our group demonstrated that rotenone, a MCI blocker, selectively occludes responsiveness to hypoxia in CB cells. In addition, our unpublished - data indicate that sensitivity to hypoxia (but not to other stimuli) is lost in mice with genetic disruption of MCI genes in CB and AM cells. We have shown that the adult CB is a plastic organ that contains a population of multipotent neural stem - cells. Hence, another objective of the project is to study the role of these stem cells in CB modulation (over- or infra-activation), which may participate in the pathogenesis of diseases. In the past, our group has made seminal contributions to - unveiling the cellular bases of arterial chemoreception. The discovery of stem cells in the CB and the generation of new genetically modified mouse models, put us in a leading position to elucidate the molecular bases of acute O2 sensing and their - biomedical implications. - - 2020-10-31, ongoing project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Spain - - - OxygenSensing - - - ERC-2014-ADG - - - 669220 - - - - - UNIVERSITE DE LORRAINE - UNIVERSITE DE LORRAINE - - - EUR 2 810 229 - - - Isotope Fractionation of Light Elements Upon Ionization: Cosmochemical and Geochemical Implications - - - EUR 2 810 229 - - - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Light elements such as hydrogen and nitrogen present large isotope variations among solar system objects and reservoirs (including planetary atmospheres) that remain unexplained at present. Works based on theoretical - approaches are model-dependent and do not reach a consensus. Laboratory experiments are required in order to develop the underlying physical mechanisms. The aim of the project is to investigate the origins of and processes responsible for isotope - variations of the light elements and noble gases in the Solar System through an experimental approach involving ionization of gaseous species. We will also investigate mechanisms and processes of isotope fractionation of atmophile elements in - planetary atmospheres that have been irradiated by solar UV photons, with particular reference to Mars and the early Earth. Three pathways will be considered: (i) plasma ionisation of gas mixtures (H2-CO-N2-noble gases) in a custom-built reactor; - (ii) photo-ionisation and photo-dissociation of the relevant gas species and mixtures using synchrotron light; and (iii) UV irradiation of ices containing the species of interest. The results of this study will shed light on the early Solar System - evolution and on processes of planetary formation. - - 2021-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - France - - - Photonis - - - ERC-2015-AdG - - - 695618 - - - - - COLLEGE DE FRANCE - COLLEGE DE FRANCE - - - EUR 2 249 196,25 - - - Anionic redox processes: A transformational approach for advanced energy materials - - - EUR 2 249 196,25 - - - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Redox chemistry provides the fundamental basis for numerous energy-related electrochemical devices, among which Li-ion batteries (LIB) have become the premier energy storage technology for portable electronics and vehicle - electrification. Throughout its history, LIB technology has relied on cationic redox reactions as the sole source of energy storage capacity. This is no longer true. In 2013 we demonstrated that Li-driven reversible formation of (O2)n peroxo-groups - in new layered oxides led to extraordinary increases in energy storage capacity. This finding, which is receiving worldwide attention, represents a transformational approach for creating advanced energy materials for not only energy storage, but also - water splitting applications as both involve peroxo species. However, as is often the case with new discoveries, the fundamental science at work needs to be rationalized and understood. Specifically, what are the mechanisms for ion and electron - transport in these Li-driven anionic redox reactions? - - - 2020-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - France - - - ARPEMA - - - ERC-2014-ADG - - - 670116 - - - - - UNIVERSIDAD DE SEVILLA - UNIVERSIDAD DE SEVILLA - - - EUR 1 106 936 - - - Analysis of moving incompressible fluid interfaces - - - EUR 1 106 936 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The research of this proposal is focused on solving problems that involve the evolution of fluid interfaces. The project will investigate the dynamics of free boundaries arising between incompressible fluids of different - nature. The main concern is well-posed scenarios which include the possible formation of singularities in finite time or existence of solutions for all time. These contour dynamics issues are governed by fundamental fluid mechanics equations such as - the Euler, Navier-Stokes, Darcy and quasi-geostrophic systems. They model important problems such as water waves, viscous waves, Muskat, interface Hele-Shaw and SQG sharp front evolution. All these contour dynamics frameworks will be studied with - emphasis on singularity formation and global existence results, not only for their importance in mathematical physics, but also for their mathematical interest. This presents huge challenges which will in particular require the use of different tools - and methods from several areas of mathematics. A new technique, introduced to the field by the Principal Investigator, has already enabled the analysis of several singularity formations for the water waves and Muskat problems, as well as to obtain - global existence results for Muskat. The main goal of this proposal is to develop upon this work, going far beyond the state of the art in these contour dynamics problems for incompressible fluids. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Spain - - - FLUID-INTERFACE - - - ERC-2014-STG - - - 639227 - - - - - THE UNIVERSITY OF SHEFFIELD - - - EUR 237 493,80 - - - “Can bean yield losses caused by drought, heat stress and climate change be ameliorated by enhancing pod-specific stomatal conductance?” - - - EUR 237 493,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - CO2-induced climate change is causing global warming and droughts, resulting in crop yield losses. Common bean (Phaseolus vulgaris) is among the most important food crops worldwide, but is very vulnerable to heat- and - drought-induced yield losses. The key objective of this project is to experimentally test the potential for increased pod transpiration to enhance bean pod yield under climate-change-associated drought and heat stress. I will fill an empirical void - by, for the first time, testing this critical hypothesis in (1) naturally drought- and heat- tolerant tepary bean (Phaseolus acutifolius) using transcriptomic analysis, and (2) by transgenic enhancement of pod-specific stomatal conductance in the - stress-intolerant common bean (P. vulgaris). For comparative transcriptomic analysis of Phaseolus pod drought and heat responses I will be trained in RNAseq, and for transgenic experiments I will produce stable Phaseolus transformants and - characterise pod water flux by cutting-edge terahertz spectroscopy during the out-going phase in the lab of Prof. Covarrubias at the Institute of Biotechnology, National Autonomous University of Mexico (IBT-UNAM). I have designed a soybean - promoter-driven construct that will direct expression of a dominant Arabidopsis allele to enhance Phaseolus pod stomatal opening and this will be compatible for use in many legume crops. To transfer this important agri-tech innovation back to Europe, - I will characterise tepary bean and the transgenic plant’s growth and yield responses to a Future Climate Change Scenario during the return phase at the beneficiary, the University of Sheffield (USFD). At the USFD the group of Prof. Gray has unique - expertise in stomatal and guard cell responses to elevated [CO2] and combines infrared thermography and infrared-gas analysis to phenotype whole-plant CO2 growth responses. The project uses an interdisciplinary and translational approach to tackle - food security issues under climate change. - - 2020-06-11, ongoing project - - - 2017-06-12 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - Pod Yield - - - H2020-MSCA-IF-2015 - - - 700867 - - - - - UNIVERSIDAD AUTONOMA DE MADRID - UNIVERSITY OF DURHAM - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - KARLSRUHER INSTITUT FUER TECHNOLOGIE - UNIVERSITAT DE VALENCIA - UNIVERSITAT ZURICH - ISTITUTO NAZIONALE DI FISICA NUCLEARE - UNIVERSITAT DE BARCELONA - GEORG-AUGUST-UNIVERSITAT GOTTINGENSTIFTUNG OFFENTLICHEN RECHTS - UNIVERSITY OF SOUTHAMPTON - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - - - EUR 3 855 581,28 - - - The Elusives Enterprise: Asymmetries of the Invisible Universe - - - EUR 3 855 581,28 - - - Spain - United Kingdom - France - Germany - Germany - Spain - Switzerland - Italy - Spain - Germany - United Kingdom - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - NEUTRINOS and DARK MATTER (DM) are the most abundant and also the most elusive building-blocks of nature because of their tenuous couplings to the ordinary matter we are made of. Each particle has a mirror image with identical - mass and opposite charge: its antiparticle. What is the essential nature of particles and antiparticles? This is a most fundamental open question in science. The laws of physics are almost -but not quite- symmetric for particles and antiparticles, - and this could explain why the universe is made of matter, i.e. why we are here. Tiny differences detected in visible matter are largely insufficient, while an asymmetric behaviour of neutrinos or of DM may be the seed. In turn, the unnaturally - symmetric behaviour of strong interactions points to a new particle, the axion, also a superb DM candidate. For the first time, the connection between these asymmetries in the visible and invisible world will be addressed. Very timely, an ambitious - experimental search of asymmetric behaviour has been launched on neutrinos, axions and other DM, and the Higgs, with imminent major breakthroughs. The path to understand the Universe and build the New Standard Model must confront this problem. The - mission of Elusives ITN is to form the new generation of researchers to accomplish this task, focusing on phenomenology with the necessary link to experiment. This is the first transnational such program, exploiting the capital investment in new - experiments and overcoming the fragmentation of the research effort. ELUSIVES ITN is uniquely placed for it: * World-leadership in all relevant areas; * Multidisciplinarity; * Key theorists and experimentalists; * Outstanding training record; * CERN, - Fermilab, SuperKamiokande and ADMX partners; * World leading cutting-edge research-related industry; * Highest professional beneficiary dissemination; * Top-quality expertise from emerging countries; * Optimal gender balance with over 50% female - international leaders as coordinators. - - 2020-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Spain - - - ELUSIVES - - - H2020-MSCA-ITN-2015 - - - 674896 - - - - - UNIVERSITA DEGLI STUDI DI MILANO - THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN - UNIVERSITEIT ANTWERPEN - UNIVERSITAT DE BARCELONA - ACADEMISCH ZIEKENHUIS LEIDEN - - - EUR 3 086 435,52 - - - Modulation of glycolytic flux as a new approach for treatment of atherosclerosis and plaque stabilization: a multidisciplinary study - - - EUR 3 086 435,52 - - - Italy - United Kingdom - Belgium - Spain - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The mission of MoGlyNet is to define a joint doctorate educational training model in Drug Discovery and Development where Academia and Industry join their forces for: - - 2019-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-EJD - Marie Skłodowska-Curie Innovative Training Networks (ITN-EJD) - - - MSCA-ITN-EJD - European Joint Doctorates - - - Italy - - - MOGLYNET - - - H2020-MSCA-ITN-2015 - - - 675527 - - - - - HUMANITAS UNIVERSITY - HUMANITAS UNIVERSITY - ISTITUTO EUROPEO DI ONCOLOGIA SRL - - - EUR 2 500 000 - - - The inflammatory gene expression program in macrophages: An integrative approach for the systematic characterization of transcriptional co-regulators - - - EUR 2 500 000 - - - Italy - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Tissue responses to microbial and endogenous danger signals involve the activation of both resident and monocyte-derived macrophages, as well as the coordinated inducible expression of hundreds of inflammatory genes. Gene - transcription is controlled by the information contained in thousands of genomic regulatory elements (enhancers and promoters), which is first read by transcription factors (TFs) and then integrated and relayed to the transcriptional machinery via an - array of co-regulators with disparate biochemical activities and functions. The recent work of several groups, including our own, has extensively characterized how in macrophages the genomic regulatory sequences controlling inflammatory gene - expression are coordinately bound and activated by myeloid lineage-determining TFs and broadly expressed stimulus-activated TFs. However, we still have a very incomplete understanding of the necessary next step in the process, namely how distinct - combinations of DNA-bound TFs regulate recruitment and function of the co-regulators and machineries that control gene transcription. - - - 2021-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Italy - - - MEDICI - - - ERC-2015-AdG - - - 692789 - - - - - ATHINA-EREVNITIKO KENTRO KAINOTOMIAS STIS TECHNOLOGIES TIS PLIROFOFORIAS, TON EPIKOLNONION KAI TIS GNOSIS - UNIVERSITAT DE BARCELONA - INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE - UNIVERSITAT LINZ - STIFTELSEN SINTEF - UNIVERSITY OF STRATHCLYDE - TECHNISCHE UNIVERSITAET WIEN - Evolute GmbH - - - EUR 3 408 202,08 - - - Algebraic Representations in Computer-Aided Design for complEx Shapes - - - EUR 3 408 202,08 - - - Greece - Spain - France - Austria - Norway - United Kingdom - Austria - Austria - - - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - ARCADES aims at disrupting the traditional paradigm in Computer-Aided Design (CAD) by exploiting cutting-edge research in mathematics and algorithm design. Geometry is now a critical tool in a large number of key applications; - somewhat surprisingly, however, several approaches of the CAD industry are outdated, and 3D geometry processing is becoming increasingly the weak link. This is alarming in sectors where CAD faces new challenges arising from fast point acquisition, - big data, and mobile computing, but also in robotics, simulation, animation, fabrication and manufacturing where CAD strives to address crucial societal and market needs. The challenge taken up by ARCADES is to invert the trend of CAD industry - lagging behind mathematical breakthroughs and to build the next generation of CAD software based on strong foundations from algebraic geometry, differential geometry, scientific computing, and algorithm design. Our game-changing methods lead to - real-time modelers for architectural geometry and visualisation, to isogeometric and design-through-analysis software for shape optimisation, and marine design & hydrodynamics, and to tools for motion design, robot kinematics, path planning, and - control of machining tools. One of the Network SMEs estimates that the innovative impact of ARCADES may enable them to get ahead of competition for up to 2 years, thus benefiting about 40% of their customers. The participants span a multidisciplinary - and multisectoral spectrum for realising our vision, all being international leaders at various stages of the pipeline. They form an outstanding ecosystem for training the next generation of applied mathematicians, computer scientists and engineers - for achieving our scientific breakthroughs, and who are equipped with a double career advantage: excellent research training, and exposure to industrial research environments through a nexus of secondments among Universities, Research and Innovation - Centers, and industrial teams. - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Greece - - - ARCADES - - - H2020-MSCA-ITN-2015 - - - 675789 - - - - - FUNDACION DEUSTO - FUNDACION DEUSTO - UNIVERSIDAD AUTONOMA DE MADRID - - - EUR 2 065 125 - - - Dynamic Control and Numerics of Partial Differential Equations - - - EUR 2 065 125 - - - Spain - Spain - Spain - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - - This project aims at making a breakthrough contribution in the broad area of Control of Partial Differential Equations (PDE) and their numerical approximation methods by addressing key unsolved issues appearing systematically - in real-life applications. - - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Spain - - - DYCON - - - ERC-2015-AdG - - - 694126 - - - - - UNIVERSIDAD PUBLICA DE NAVARRA - - - EUR 170 121,60 - - - Disentangling the effects of CO2 fertilization, nutrient limitation and water availability on forest ecosystem processes: Estimating their long-term consequences on SW European forests - - - EUR 170 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - European forestry is fast evolving as forests could experience in the near future important changes in climate and also in management, which is moving from timber production to values such as bioenergy, carbon sequestration, - biodiversity and others. These factors could change the idoneity of traditional forestry in Scots pine forests (which cover important areas in Europe). The project´s objectives are: 1) To characterize past and estimate future effects of forest - management and climate change on carbon and nutrient budgets in Pinus sylvestris stands in SW Europe, to support sustainable forestry that maximizes nutrient and carbon use efficiency and therefore tree growth; 2) To develop, evaluate and apply - reliable ecologically-based mathematical models that can be applied in forest management, to study interactions among elevated atmospheric CO2, tree growth and limiting nutrients and moisture. To achieve these objectives the project will be - implemented in three stages: 1) Field and archival samples form experimental plots in Scot pine stands in the Pyrenees will be used to analyze connections between soil, leaf and stem nutrient status in the last 16 years. The magnitude of ecosystem - biomass and nutrient pools will be estimated to calculate the historical change of nutrient use efficiency by the pines. Historical leaf NUE will be estimated through leaf area scanning combined with chemical analysis. Stem water and nutrient status - will be estimated by wood scanning combined with techniques discriminating isotopes of carbon and nitrogen. 2) The ecosystem model FORECAST-Climate will be calibrated, validated, and used as a virtual lab to test the relative importance of nutrient, - water, and CO2 availability on tree growth. 3) A battery of climate change (temperature, precipitation and CO2 concentration) and forest management scenarios will be simulated to assess their long-term consequences and provide guidelines on the - potential consequences of each management option. - - 2018-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - DENDRONUTRIENT - - - H2020-MSCA-IF-2014 - - - 656810 - - - - - UNIVERSIDAD AUTONOMA DE MADRID - - - EUR 1 274 400 - - - Programme for Post-Doctoral Talent Attraction to CEI UAM+CSIC - - - EUR 2 548 800 - - - Spain - - - Higher or Secondary Education Establishments - - The Programme for Post-Doctoral Talent Attraction to CEI UAM+CSIC, InterTalentum, is a programme developed by the Universidad Autónoma de Madrid (UAM), which intends on building particularly favourable environment to attract - the best experienced researchers in the four Focus Research Areas of CEI UAM+CSIC: Biology and Biomedicine, Nanoscience, Nanotechnology and Advanced Materials, Theoretical Physics and Mathematics and Social Sciences, Legal Sciences and Humanities. - The program aims at exploiting the full potential of the CEI UAM+CSIC to offer the fellows a truly interdisciplinary and intersectorial training that will strengthen their curricula and provide the region of Madrid with a pool of researchers capable - of preserving the long standing tradition for scientific excellence and bridging the gap between academic and applied research. Within the proposed 60 months co-funding period (48 months of fellowships), distributed in two International Calls, - InterTalentum will offer to 18 incoming experienced researchers, of any nationality, the opportunity to develop her/his research project within the framework of a vast network of institutions participating under CEI UAM+CSIC, an International - Excellence initiative and a Global Campus, including some worldwide reference research laboratories at Universidad Autónoma de Madrid (UAM, included its Joint Research Institutes and Health Institutes), Consejo Superior de Investigaciones científicas - (CNB - Centro Nacional de Biotecnología, ICMM - Instituto de Ciencia de Materiales de Madrid, ICP - Instituto de Catálisis y Petroquímica , ICV - Instituto de Cerámica y Vidrio, IMM - Instituto de Microelectrónica de Madrid), Madrid Advanced Research - Institutes “IMDEAS” (IMDEA – Alimentación, IMDEA Nanociencia). Researchers will be selected through a transparent and international evaluation process taking into consideration the whole range of experience of the candidates. - - 2021-05-31, ongoing project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2015-FP - Marie Skłodowska-Curie Co-funding of regional, national and international programmes (COFUND-FP) - - - MSCA-COFUND-FP - Fellowship programmes - - - Spain - - - InterTalentum - - - H2020-MSCA-COFUND-2015 - - - 713366 - - - - - UNIVERSITE PARIS III SORBONNE NOUVELLE - - - EUR 173 076 - - - Francophone African and Caribbean Theaters - - - EUR 173 076 - - - France - - - Higher or Secondary Education Establishments - - The cultural and artistic expressions of Black minorities are still unknown, devalued, and understudied in France today where exclusion and discrimination keep growing. Therefore it is urgent to analyze and recognize the work - of African and Caribbean dramatists who embody the diversity and multiculturalism of our global contemporary world. The goal of FACT (Francophone African & Caribbean Theaters) is to revisit the history of Francophone Black theaters born out of - the brutal encounter of Europe, Africa and the Americas, and to evaluate the effects of colonialism and postcolonialism on contemporary France. This colonial legacy is still denied today although being an integral part of the French national history. - As a specialist of Caribbean theater, I will join the Theater studies Department at the University Sorbonne Nouvelle to collaborate with Professor Chalaye, specialist of African drama, to examine plays written by dramatists from Africa and the - Caribbean from the 1960s to date. We intend to show that migrations that followed decolonization have transformed, nourished and enriched the French nation. We also want to challenge not only stereotypes and prejudices against Black minorities, but - also the conception of a homogeneous unique French identity. FACT will contribute to make Francophone African and Caribbean drama more visible in the field by creating a database of texts and audio/videorecordings and by developing a postcolonial - analysis of the materials. The outcome of FACT will create awareness among the general public of the reality of a multi-racial and multi-cultural nation born of a shared colonial history with the ultimate goal to encourage French and European - citizens to lose their fears of the “Other,” to be opened to the difference, and to welcome and celebrate the diversity of Europe. - - 2017-05-31, closed project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - FACT - - - H2020-MSCA-IF-2014 - - - 657877 - - - - - UNIVERSIDAD DE SEVILLA - UNIVERSIDAD DE SEVILLA - - - EUR 2 312 500 - - - R-loops as a major modulator of transcription-associated recombination and chromatin dynamics - - - EUR 2 312 500 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Understanding the causes of genome instability, a condition linked to cancer and cancer-prone genetic diseases, is a major question in Molecular Biology and Biomedicine. Probably the most important natural cause of genome - instability is transcription, which is known to induce both mutation and recombination from bacteria to human cells. Different studies suggest that transcription-associated recombination (TAR) is in large part due to collisions between transcription - and replication, but increasing evidence indicate that R-loops, formed by a DNA-RNA hybrid and a displaced single-stranded DNA, may be a major determinant of genome instability. This is of particular relevance, provided our recent observation that - tumor suppressor BRCA2 gene is involved in R-loop prevention/resolution and that, therefore, R-loops may represent a major potential source of tumorigenesis. The goal of this project is to understand the mechanisms of R-loop dynamics by identifying - the functions and elements acting in cis and trans, that is, the DNA sequences and genes controlling R-loop formation and removal. The project will be based on a multidisciplinary approach using Saccharomyces cerevisiae and human cell lines. We plan: - a) to identify the proteins and mechanism that actively works in the formation and prevention of intermediates responsible for R-loop-mediated TAR; b) to define the histone residues linked to R-loop formation and its role in chromatin dynamics, and - c) to establish how the different trans and cis elements control genome-wide R-loop–mediated genome instability whether or not in association with replication fork impairment, double-strand break accumulation, chromatin structure and mRNP biogenesis - and export. The functional relevance of selected conserved genes will be validated in Caenorhabditis elegans as a model organism. The long-term objective of the proposal is to decipher the mechanisms by which R-loops modulate chromatin dynamics and - genome instability. - - 2020-11-30, ongoing project - - - 2015-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Spain - - - TARLOOP - - - ERC-2014-ADG - - - 669898 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 2 348 938 - - - Duality in Formal Languages and Logic - a unifying approach to complexity and semantics - - - EUR 2 348 938 - - - France - France - - - Research Organisations - Research Organisations - - Dualities between algebraic and topological structure are pervasive in mathematics, and toggling back and forth between them has often been associated with important breakthroughs. The main objective of this project is to - bring this important tool to bear on a number of subjects in theoretical computer science thereby advancing, systematising, and unifying them. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - France - - - DuaLL - - - ERC-2014-ADG - - - 670624 - - - - - UNIVERSITEIT ANTWERPEN - - - EUR 172 800 - - - Warmed Icelandic Soils, Lipids and Sequencing: towards a better understood climate proxy - - - EUR 172 800 - - - Belgium - - - Higher or Secondary Education Establishments - - The distribution of the soil bacterial membrane lipids “branched glycerol dialkyl glycerol tetraethers” (brGDGTs) in geological records has been used to reconstruct palaeoclimatic conditions, specifically the mean annual air - temperature and soil pH. However, the large error associated with the most recent brGDGT-based calibration, makes this method unsuitable for determining absolute temperatures. The fellow aims to perform geochemical and microbiological work that will - result in the improvement of this palaeotemperature proxy. Firstly, an improved analytical method will be used, targeting not only fifteen brGDGTs that are currently used for palaeoclimate reconstructions, but including an additional fifteen brGDGT - lipids, and a suite of precursors, whose diversity in soils is unstudied. This extended dataset will be measured in a well-studied, naturally (geothermally) warmed soil, linking the observed lipid distributions directly to the measured in-situ soil - temperature (covering a 0-35°C gradient). Furthermore, the applicability of the novel temperature proxy proposed, will be tested in a well-studied dataset of European soils, covering a latitudinal temperature gradient. Although environmental studies - point towards the Acidobacteria as the source organism, only one brGDGT has been found in an Acidobacterial culture so far and brGDGTs are still considered to be “orphan lipids”. Using a novel approach to identify the source organism, the fellow - proposes to study the microbial community using a next-generation sequencing method. Tracking the patterns in (Acido)bacterial distribution along a temperature gradient, will enable the fellow to ascertain if the changes in the brGDGT pool are caused - by a shift in the microbial community, or are caused by phenotypic plasticity. This interdisciplinary project will improve the accuracy and interpretation of lipid-based palaeoclimate reconstructions and will extend the applicant’s scientific - experience and career perspectives. - - 2018-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Belgium - - - WISLAS - - - H2020-MSCA-IF-2015 - - - 707270 - - - - - UNIVERSIDAD AUTONOMA DE MADRID - UNIVERSIDAD AUTONOMA DE MADRID - - - EUR 1 987 750 - - - Unconventional Bifunctional Catalysts - - - EUR 1 987 750 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The development of sustainable chemical processes is one of the most important features in modern chemistry. It has become a key research area worldwide providing solutions to important societal demands by optimizing the use - of natural resources and minimizing waste and environmental impact. Among the relevant methods for achieving this goal, catalysis represents a key and central approach. Both Organocatalysis and Metal Catalysis have emerged as solutions to the - problems in this context. In this field, the progress of a novel bifunctional organocatalyst that could increase the number of different activations, and therefore the synthesis of valuable enantio-enriched molecules, would be highly desirable. - Especially important, but still unknown, are the bifunctional-catalysts based on a Neutral Coordinate Organocatalyst and Photo-Organocatalysts. This proposal aims to develop two new unconventional approaches for the synthesis of bifunctional - organocatalysts. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Spain - - - UNBICAT - - - ERC-2014-CoG - - - 647550 - - - - - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 185 076 - - - Control of the Homeostasis of Actin through Time: actin homeostasis during embryonic development by means of single-molecule imaging and simulation in C. elegans - - - EUR 185 076 - - - France - France - - - Research Organisations - Research Organisations - - In embryonic cells, actomyosin forms a cortical reticulated gel that turns over rapidly, is weakly organized, and is composed of a variety of structures, with distinct architectures and dynamics, which are nucleated and - elongated by different factors, and bind to specific sets of actin-binding proteins that modulate their dynamics. Understanding how actin is distributed between these structures is critical to understand the biology and mechanics of the actin - cytoskeleton and therefore its role in processes ranging from morphogenesis and cell division to endocytosis and polarization. - - 2017-03-31, closed project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - France - - - CHAT - - - H2020-MSCA-IF-2014 - - - 661451 - - - - - WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER - WIRTSCHAFTSUNIVERSITAT WIEN - UNIVERSIDAD DE SEVILLA - TECHNISCHE UNIVERSITEIT EINDHOVEN - PICTURE GMBH - CUPENYA BV - - - EUR 855 000 - - - Propelling Business Process Management by Research and Innovation Staff Exchange - - - EUR 1 273 500 - - - Germany - Austria - Spain - Netherlands - Germany - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - RISE_BPM networks world-leading research institutions and corporate innovators to develop new horizons for Business Process Management (BPM). BPM is a boundary-spanning discipline focused on division and re-integration of - day-to-day work in organisations and on analysis of process data for organisational decision-making. Recent break-through innovations in Social Computing, Smart Devices, Real-Time Computing, and Big Data Technology create a strong impetus for - propelling BPM into a pervasive corporate topic that enables design of entirely new products and services. - - 2019-04-30, ongoing project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Germany - - - RISE_BPM - - - H2020-MSCA-RISE-2014 - - - 645751 - - - - - UNIVERSITEIT UTRECHT - - - EUR 177 598,80 - - - Controlling micro- and nano-channel transport with selective solvation - - - EUR 177 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - The motivation for the COMNACTSS project comes from recent evidence that the selective solvation of ions in liquid mixtures has a dramatic influence on the interaction between colloids. Selective solvation introduces a new - energy scale that is comparable with or often exceeds the thermal energy and this energy can be utilized for the dispersion of uncharged nano-particles, offering a polymer-and-surfactant-free pathway to nano-particle stabilization. The combination of - a large energy-scale and chemical specificity offers a new handle for inducing liquid structuring and controlling flow at interfaces in confined and heterogeneous environments. I therefore propose to study theoretically, and by using molecular - simulations, selective solvation in micro- and nano-fluidics. The research objectives are (i) gaining fundamental understanding of the dynamics of salt-containing mixtures in micro- and nano-fluidic channels and using it to investigate the transport - of macromolecules through such channels. The use of salty mixtures will enable to greatly increase the transport of ions and macromolecules through pores, and the ability to control this transport, a key issue in science and technology. (ii) To - uncover novel liquid-liquid interface destabilization mechanisms. The COMNACTSS project will advance the field of nanofluidics by introducing a new research paradigm which will enable new fundamental insights into the molecular organization and - dynamics of complex fluids, with excellent potential to produce applications. - - 2017-08-31, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - COMNACTSS - - - H2020-MSCA-IF-2014 - - - 656327 - - - - - HELMHOLTZ-ZENTRUM GEESTHACHT ZENTRUM FUR MATERIAL- UND KUSTENFORSCHUNG GMBH - AIRBUS DEFENCE AND SPACE GMBH - UNIVERSIDADE DE AVEIRO - SMALLMATEK - SMALL MATERIALS AND TECHNOLOGIES LDA - - - EUR 648 000 - - - MULTI-functional metallic SURFaces via active Layered Double Hydroxide treatments - - - EUR 648 000 - - - Germany - Germany - Portugal - Portugal - - - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The main objective of the proposal is development of active multi-functional surfaces with high level of self-healing ability on the basis of Layered Double Hydroxide (LDH) structures formed on different industrially relevant - metallic substrates. The main idea of the project is based on “smart” triggered release on demand for functional organic or inorganic anionic compounds intercalated into intergallery spaces of LDHs. The active functionality is achieved via - controllable substrate-governed growth of LDH architectures on Al, Mg and Zn based alloys. The functional anions such as corrosion inhibitors, biocides, drugs, or hydrophobic agents are introduced into the intergallery spaces during the growth of LDH - or upon a post-treatment stage. The release of the functional agents occurs only on demand when the respective functionality is triggered by the relevant external stimuli such as presence of anions or local pH change. - - - 2018-12-31, ongoing project | - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Germany - - - MULTISURF - - - H2020-MSCA-RISE-2014 - - - 645676 - - - - - UNIVERSIDAD AUTONOMA DE MADRID - NARODOWE CENTRUM BADAN JADROWYCH - POLITECHNIKA WARSZAWSKA - - - EUR 310 500 - - - Super-Kamiokande plus - - - EUR 310 500 - - - Spain - Poland - Poland - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - - This proposal is a part of ongoing global efforts to understand the most fundamental elements of matter and their interactions. We aim to investigate neutrino interactions using the existing experimental facility in Japan, the - Super-Kamiokande (SK) detector located in the Kamioka Observatory (Gifu Prefecture) and owned by the Partner of this Project: the Institute for Cosmic Ray Research of the University of Tokyo. - - - 2018-11-30, ongoing project - - - 2014-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Spain - - - SKPLUS - - - H2020-MSCA-RISE-2014 - - - 641540 - - - - - UNIVERSITA CA' FOSCARI VENEZIA - - - EUR 250 518,60 - - - Neurodidactics of Performing Arts: The Impact of Drama Teaching on Second Language Acquisition - - - EUR 250 518,60 - - - Italy - - - Higher or Secondary Education Establishments - - Since the 1990s, Educational Neuroscience has become an emerging field of research which studies cognitive brain functions (thinking, memory, attention, emotions) and interfaces with the educational environment with the aim of - improving teaching and learning. Simultaneously, "Drama Teaching", a teaching methodology based on performing arts introduced in the 1970s, is now generating interest, especially in Foreign Language Learning. This research project will investigate - aspects of cognition involved in the language learning process and it will analyse how Drama Teaching dynamics can impact language learning and proficiency. In order to define Drama Teaching as a methodology which involves the brain-mind-body - dimension and fosters development of the learner as a whole person, a cognitive perspective will be adopted in relation to issues of a) embodied cognition, b) role of emotions in learning, c) impact of context and experience on learning d) - cross-cultural identity process, development and awareness. Theoretical scientific investigation will be conducted on cognitive aspects relevant to learning, followed by the study and observation of dramatization practices. Development of curriculum - and course implementation will follow. Particular attention will be given to the assessment of learning results and proficiency levels, as well as to the cognitive and emotional factors. The inter-disciplinary perspective adopted by this study is - aimed at contributing to the debate on creative, interactive Foreign Language Education taking place in Europe and in the world. The scope is to contribute to the multi-disciplinary inquiries of Educational Neuroscience by elaborating a - neuroscientifically grounded theory of Drama Teaching which gives educators guidelines to expand the range of teaching possibilities in accordance with the principles of Learning/Teaching of the "Common European Framework of Reference for Languages". - - 2018-06-21, ongoing project - - - 2015-06-22 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Italy - - - NPA - - - H2020-MSCA-IF-2014 - - - 660495 - - - - - UNIVERSITAET POTSDAM - UNIVERSITE PARIS DESCARTES - JYVASKYLAN YLIOPISTO - NIRX MEDIZINTECHNIK GMBH - UNIVERSIDAD POMPEU FABRA - - - EUR 3 848 639,76 - - - Understanding and predicting developmental language abilities anddisorders in multilingual Europe - - - EUR 3 848 639,76 - - - Germany - France - Finland - Germany - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - PredictAble aims to train a new generation of young scientists at the crossroads between academic research, technological development in the private sector and clinical practice to pioneer an interdisciplinary approach to - language related developmental disorders, like specific language impairment (SLI) and developmental dyslexia (DD). The innovative and timely research program will enhance the understanding of the cognitive mechanisms that underlie developmental - disorders of spoken and written language by pooling international experts from academia and the private sector. For the first time, PredictAble applies a truly multidisciplinary and cross-linguistic perspective with a unique and novel combination of - cutting-edge approaches and techniques for studying mono- and bilingual children. Thus, PredictAble will provide young researchers with an excellent foundation for making scientific progress in this area, in collaboration with technology development - and the transfer of research outcomes to applicants in the private sector and the health sector/clinical practice. Highly recognized experts in the area of language acquisition in very young mono- and bilingual children will work together on the - acquisition of spoken and written language in a cross-linguistic approach. The complementarity of the different languages in PredictAble will make it possible to identify language-specific and cross-linguistically valid effects. In cooperation with - technological partners from the private sector, PredictAble will optimize recently developed technologies in the area of developmental cognitive neuroscience to render them suitable for use with very young children and as diagnostic tools to detect - early risks for language-related impairments. - - 2019-02-28, ongoing project | - - - 2015-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - PREDICTABLE - - - H2020-MSCA-ITN-2014 - - - 641858 - - - - - CLARIN ERIC - UNIVERZITA KARLOVA - EBERHARD KARLS UNIVERSITAET TUEBINGEN - KOBENHAVNS UNIVERSITET - - - EUR 1 495 300 - - - Strengthening the CLARIN Infrastructure. - - - EUR 1 495 300 - - - Netherlands - Czech Republic - Germany - Denmark - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - CLARIN, the Common Language Resource and Technology Research Infrastructure, has gained force and momentum over the last 10 years. It is being constructed as a distributed e-infrastructure for the Humanities and Social - Sciences to enable sustainable access, exploitation and integration of Europe’s vast amount of language-based data and related technology. - - - 2017-12-31, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-3-2015 - Individual implementation and operation of ESFRI projects - - - RIA - Research and Innovation action - - - Netherlands - - - CLARIN-PLUS - - - H2020-INFRADEV-1-2015-1 - - - 676529 - - - - - POLITECNICO DI MILANO - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - UNIVERSIDAD DE SEVILLA - - - EUR 450 000 - - - Sustainable Design and Management of Industrial Assets through Total Value and Cost of Ownership - - - EUR 450 000 - - - Italy - United Kingdom - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - SoThe project will examine the potential of Total Value and Cost of Ownership (TVO, TCO) for supporting the design and through-life management of industrial assets. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Italy - - - Sustain-Owner - - - H2020-MSCA-RISE-2014 - - - 645733 - - - - - NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU - NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO - NATURAL ENVIRONMENT RESEARCH COUNCIL - STIFTELSEN SINTEF - FUNDACION CIUDAD DE LA ENERGIA - PANSTWOWY INSTYTUT GEOLOGICZNY - PANSTWOWY INSTYTUT BADAWCZY - ISTITUTO NAZIONALE DI OCEANOGRAFIA E DI GEOFISICA SPERIMENTALE - SINTEF ENERGI AS - ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS - SOTACARBO - SOCIETA TECNOLOGIE AVANZATE CARBONE SPA. - Eidgenössische Technische Hochschule Zürich - GLOWNY INSTYTUT GORNICTWA - SINTEF PETROLEUM AS - BUREAU DE RECHERCHES GEOLOGIQUES ET MINIERES - - - EUR 3 252 279 - - - European Carbon Dioxide Capture and Storage Laboratory Infrastructure - - - EUR 3 252 279,60 - - - Norway - Netherlands - United Kingdom - Norway - Spain - Poland - Italy - Norway - Greece - Italy - Switzerland - Poland - Norway - France - - - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - - ECCSEL aims at gaining recognition as a world-class research infrastructure based within leading European Carbon Capture and Storage (CCS) institutions and knowledge centres. It will be due for registration in 2015, forming a - legal entity allocating efforts and resources to selected scientific and technological aspects of the CCS chain. - - - 2017-08-31, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-3-2015 - Individual implementation and operation of ESFRI projects - - - RIA - Research and Innovation action - - - Norway - - - ECCSEL - - - H2020-INFRADEV-1-2015-1 - - - 675206 - - - - - UNIVERSIDAD AUTONOMA DE MADRID - UNIVERSITY OF DURHAM - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH - UNIVERSITAT DE VALENCIA - UNIVERSITAT ZURICH - ISTITUTO NAZIONALE DI FISICA NUCLEARE - UNIVERSITAT DE BARCELONA - GEORG-AUGUST-UNIVERSITAT GOTTINGENSTIFTUNG OFFENTLICHEN RECHTS - UNIVERSITY OF SOUTHAMPTON - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 2 070 000 - - - InvisiblesPlus - - - EUR 2 322 000 - - - Spain - United Kingdom - France - Germany - Switzerland - Spain - Switzerland - Italy - Spain - Germany - United Kingdom - Germany - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - NEUTRINOS (Ns) and DARK MATTER (DM) are the most abundant particles in the universe. Their couplings to ordinary matter are so tenuous that they remained undiscovered -invisible- until very recently. N masses and DM constitute - the first evidence ever of physics beyond the Standard Model of particle physics. The path to build the New Standard Model must confront the fundamental nature of the particles in the invisible sector at large. Furthermore, for each particle there is - a mirror image with identical mass and opposite charge(s): its antiparticle. The laws of physics are almost particle-antiparticle symmetric: an asymmetry in Ns and/or DM properties may be the required seed that explains why the universe is made of - matter and not antimatter, i.e. how come we are here, a fact unexplained by standard physics. In turn, the unnaturally symmetric behavior of strong interactions points to a new particle, the axion, a superb dark matter candidate. Very timely, an - ambitious international experimental search has been launched on Ns, axions, other DM and Higgs physics with major breakthroughs expected soon. - - 2020-01-31, ongoing project - - - 2016-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Spain - - - InvisiblesPlus - - - H2020-MSCA-RISE-2015 - - - 690575 - - - - - UNIVERSIDAD AUTONOMA DE MADRID - KATHOLIEKE UNIVERSITEIT LEUVEN - RIJKSUNIVERSITEIT GRONINGEN - UNIVERSITE PAUL SABATIER TOULOUSE III - UNIVERSITA DEGLI STUDI DI PERUGIA - UNIVERSITAT WIEN - UNIVERSITAT DE BARCELONA - UNIVERSITA DI PISA - UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6 - UNIVERSIDADE DO PORTO - UNIVERSITAT DE VALENCIA - UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA - - - EUR 3 785 867,52 - - - Theoretical Chemistry and Computational Modelling - - - EUR 3 785 867,52 - - - Spain - Belgium - Netherlands - France - Italy - Austria - Spain - Italy - France - Portugal - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Theoretical Chemistry and Computational Modelling (TCCM) is emerging as a powerful tool to help in the rational design of new products and materials for pharmaceutical, chemical, energy, computer, and new-materials industries. - To achieve this goal, it is necessary to go beyond the traditional electronic structure studies, and merge complementary techniques that are normally not available at a single research group. The research programme of the TCCM-EJD aims at applying - computational modelling to problems demanded by the industry and with high societal relevance, namely Materials with special properties, Biomolecules for new therapies and Energy storage. The objective of the Joint Doctorate is to prepare future - research leaders, able to develop and use multidisciplinary computational techniques (methods and software), with solid communication skills, with many contacts established through the intensive relationship with worldwide leading researchers of 12 - European universities and 14 additional partners, including 7 industrial and spin-off companies. A Joint Doctorate in TCCM is already operative since 2011, based on a fully participative scientific discussion and assessment of all research projects - with a clear interdisciplinary character and the direct participation of the non-academic sector. The training programme puts the emphasis in common training, including 3 annual International Workshops, 3 schools on High Performance Computing and 3 - tutorials in new computer codes. Career development opportunities are enhanced with regular inter-sectoral activities, transferable skill education and career coaching. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-EJD - Marie Skłodowska-Curie Innovative Training Networks (ITN-EJD) - - - MSCA-ITN-EJD - European Joint Doctorates - - - Spain - - - TCCM - - - H2020-MSCA-ITN-2014 - - - 642294 - - - - - POLITECNICO DI MILANO - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - UNIVERSITEIT GENT - TECHNISCHE UNIVERSITEIT EINDHOVEN - SORIN GROUP ITALIA SRL - PHILIPS MEDICAL SYSTEMS NEDERLAND BV - MATERIALISE NV - BIOENGINEERING LABORATORIES - LIFETEC GROUP BV - FEOPS NV - - - EUR 3 835 204,56 - - - MUltiSectoral Integrative approaches to CArdiac care - - - EUR 3 835 204,56 - - - Italy - United Kingdom - Belgium - Netherlands - Italy - Netherlands - Belgium - Italy - Netherlands - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - MUltiSectoral Integrative approaches to CArdiac care – MUSICARE - is proposed by a team of universities, companies and hospitals from 4 EU countries (Italy, United Kingdom, The Netherlands, Belgium). The main scope of - MUSICACARE is to structure a new trans-sectoral and multidisciplinary network capable of developing research and technology with no barriers between academia, industries and clinicians in the cardiac arena, and of shaping young researchers with a - novel and truly multidisciplinary mindset, capable of developing clinical- and business-oriented technology including tools for the advancement of base knowledge. MUSICARE activity will impact on the field of cardiac surgery in three ways: - - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Italy - - - MUSICARE - - - H2020-MSCA-ITN-2014 - - - 642458 - - - - - PANEPISTIMIO KRITIS - TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY - TECHNISCHE UNIVERSITAET WIEN - - - EUR 648 000 - - - Non-Hermitian Quantum Wave Engineering - - - EUR 648 000 - - - Greece - Israel - Austria - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The concept of parity-time (PT)-symmetry is extensively studied now owing to the ubiquitous applications within the fields of optics, photonics, and plasmonics. Among the many recent developments in PT-systems, the application - of pseudo-Hermitian ideas not only promises a new generation of photonic and plasmonic components such as lasers, spasers, modulators, waveguides, and detectors, but also opens new avenues for innovative electronics architectures for signal - manipulation from integrated circuits to antenna arrays, and allows for direct contact with cutting edge technological problems appearing in (nano)-antenna theory, split-ring resonator arrays, and metamaterials. More recently, potential applications - have also been proposed in connection with magnetic and acoustic structures. - - - 2020-02-29, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Greece - - - NHQWAVE - - - H2020-MSCA-RISE-2015 - - - 691209 - - - - - DESCUBRE - FUNDACION ANDALUZA PARA LA DIVULGACION DE LA INNOVACION Y EL CONOCIMIENTO - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - UNIVERSIDAD DE MALAGA - UNIVERSIDAD DE ALMERIA - UNIVERSIDAD DE GRANADA - UNIVERSIDAD DE CADIZ - UNIVERSIDAD DE CORDOBA - INSTITUTO MUNICIPAL DE GESTION MEDIOAMBIENTAL - JARDIN BOTANICO DE CORDOBA - UNIVERSIDAD DE SEVILLA - UNIVERSIDAD DE JAEN - UNIVERSIDAD PABLO DE OLAVIDE - AYUNTAMIENTO DE MALAGA - CONSEJERIA DE ECONOMIA INNOVACION CIENCIA Y EMPLEO - INSTITUTO ANDALUZ DE INVESTIGACIONY FORMACION AGRARIA PESQUERA ALIMENTARIA Y DE LA PRODUCCION ECOLOGICA - - - EUR 159 000 - - - RESEARCHERS SQUARE - - - EUR 422 423,75 - - - Spain - Spain - Spain - Spain - Spain - Spain - Spain - Spain - Spain - Spain - Spain - Spain - Spain - Spain - - - Other - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - - ‘Researchers Square’ is designed to increase the awareness of research as a solution to the numerous challenges faced by people all around the world and mainly in Europe. The idea of the project, ‘Better Living through - Science: from Social Sciences and Humanities to Maths and Technology’, has been conceived in times of crisis, a moment where becomes clearer that we must join efforts to find innovative solutions to encourage young people’s interest in research. It - responds also to the challenge of building bridges between researchers and general public, showing that science could give answer to the societal challenges that we are facing in Europe. - - 2015-11-30, closed project - - - 2014-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.5."> - - - MSCA-NIGHT-2014 - European Researchers' Night (NIGHT) - - - CSA - Coordination and support action - - - Spain - - - RESSQUA - - - H2020-MSCA-NIGHT-2014 - - - 633304 - - - - - UNIVERSITAET POTSDAM - ENZA ZADEN RESEARCH & DEVELOPMENT BV - BIOATLANTIS - - - EUR 1 268 698,32 - - - Genetic and molecular priming approaches to increase crop strength and stress tolerance - - - EUR 1 268 698,32 - - - Germany - Netherlands - Ireland - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The project provides advanced systems biology training for 5 ESRs who will develop novel methods for increasing crop strength and resistance to stress by alternative genetic and genomic, non-GMO, technologies: (1) Selecting - allelic variants of a novel gene identified by members of the consortium which regulates oxidative and abiotic stress tolerance and (2) Molecular priming by biostimulants or low doses of H2O2 to induce stress-protective mechanisms in crops. This dual - approach will meet the growing EU push towards secure, sustainable and safe means of food production (Dir.2009/128/EC & EU Reg. EC/178/2002). The genetic approaches are combined with high-throughput technologies for transcriptome, metabolome, and - phenotypic analyses, combined with advanced bioinformatics. Both approaches to increasing crop yield are growing in importance, with the biostimulants industry expected to reach $2.2B globally by 2018. Equipping ESRs with these skills will enable - them to develop their research careers in academia or industry. Training will be conducted at the University of Potsdam (UP, Coordinator), Germany, and two companies: BioAtlantis (BA), Ireland, and Enza Zaden (EZ), The Netherlands. Prof. B. - Mueller-Roeber (UP) has extensive research management and teaching experience and will supervise the ESRs as PhD students. BA is internationally recognized for producing innovative biostimulants and has 3 patents filed, while EZ is among the top ten - in vegetable breeding worldwide. All partners have experience in coordination and participation in EU FP7 projects. The expected results will increase our understanding of the molecular basis of stress tolerance and provide two alternative strategies - for crop improvement and increasing food production. BA and EZ will ensure rapid dissemination of applied research to end users. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-EID - Marie Skłodowska-Curie Innovative Training Networks (ITN-EID) - - - MSCA-ITN-EID - European Industrial Doctorates - - - Germany - - - CropStrengthen - - - H2020-MSCA-ITN-2014 - - - 642901 - - - - - COMUNE DI GENOVA - ASSOCIAZIONE FESTIVAL DELLA SCIENZA - CONSIGLIO NAZIONALE DELLE RICERCHE - FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA - UNIVERSITA DEGLI STUDI DI GENOVA - SIIT SOCIETA CONSORTILE PER AZIONI SIGLABILE SIIT SCPA - IL GIARDINO LETTERARIO DELFINO ASSOCIAZIONE - DISTRETTO LIGURE DELLE TECNOLOGIE MARINE SCRL - - - EUR 160 000 - - - Party do not stop. Having fun with researchers - - - EUR 160 531,25 - - - Italy - Italy - Italy - Italy - Italy - Italy - Italy - Italy - - - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Other - Research Organisations - Research Organisations - Chiara Andreoli - Tel.: +3901071781854 - Fax: +39 010 7170817 - Higher or Secondary Education Establishments - Other - Other - Research Organisations - - """Party do not stop"" includes the proposal of two editions of the Researchers' Night to be carried out in Liguria in 2014 and 2015. - - - 2015-12-31, closed project - - - 2014-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.5."> - - - MSCA-NIGHT-2014 - European Researchers' Night (NIGHT) - - - CSA - Coordination and support action - - - Italy - - - Party do not stop - - - H2020-MSCA-NIGHT-2014 - - - 633306 - - - - - UNIVERSITAT AUTONOMA DE BARCELONA - UNIVERSITAT DE BARCELONA - UNIVERSIDAD DE SEVILLA - MIDDLESEX UNIVERSITY HIGHER EDUCATION CORPORATION - TAMPEREEN YLIOPISTO - UNIVERSIDADE DA CORUNA - UNIVERSIDAD DE LA LAGUNA - UNIVERSITA DEGLI STUDI DI MILANO - UNIVERSITA DELLA CALABRIA - UNIVERSITE DE TOULOUSE II - LE MIRAIL - - - EUR 2 344 500 - - - Global trends in social inequalities in Europe and Latin America and exploring innovative ways to reduce them through life, occupational and educational trajectories research to face uncertainty - - - EUR 2 344 500 - - - Spain - Spain - Spain - United Kingdom - Finland - Spain - Spain - Italy - Italy - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The overall aim of this project is to create an International Network for Comparative Analysis of Social Inequalities (INCASI) with 19 universities, 10 from Europe and 9 from Latin America. The purpose is to conduct - comparative research in the area of social inequalities. Through this network we hope to foster a space for collective reflection and the development of synergies between network partners that allow us to undertake innovative studies whose outputs - have an impact on academic and policy debates on the subject. The project will also contribute to informing the design of public policies to tackle social inequalities. In so doing, we aim to contribute innovative solutions that improve citizens’ - living standards, reduce social inequalities and promote social justice. This is in line with Horizon 2020’s objectives. - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Spain - - - INCASI - - - H2020-MSCA-RISE-2015 - - - 691004 - - - - - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - POLO D'INNOVAZIONE DI GENOMICA, GENETICA E BIOLOGIA SCARL - UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA - UNIVERSITA DEGLI STUDI DI PERUGIA - MICROTEST MATRICES LTD - GENIALIS D.O.O - - - EUR 1 053 000 - - - Monitor population immunity against vaccine preventable diseases - - - EUR 1 053 000 - - - United Kingdom - Italy - Italy - Italy - United Kingdom - Slovenia - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - In the recent years an unprecedented effort has been made to increase the rates of childhood immunization in resource poor countries. This has translated into an increased number of children receiving vaccines and a parallel - decrease in the rate of illnesses from vaccine preventable diseases. However, in some regions it has proven difficult to achieve optimal levels of immunization mainly because of issues concerning communication, management and poor utilization of - resources. Recent studies have questioned the validity of available vaccine coverage data and the way they are collected. Currently, both the progress of the vaccination programs and indirectly the level of protection in a population are inferred on - the basis of administrative records. This largely unverified information is also utilized as performance indicator to allocate funds from government and donor agencies. Such self-certification practice does not incentivize the optimization of - resources while it has been increasingly questioned in terms of its validity and integrity. We propose to develop and validate an innovative technical solution based on an assay system that integrates multiplex capability and analytical performance, - to simultaneously quantify antibody levels against the major vaccine components, with both automation and wireless connectivity to produce spatial-temporal co-ordinates of individual determinations. The multiplex capability will facilitate the - analysis of cross coverage monitoring while generating reactivity profiles against the different vaccine components to discriminate vaccinated versus infected individuals. Spatial temporal co-ordinates of assay results will be used to generate - interactive data sets for modeling changes in the age-specific risk of infection and the risk of outbreaks. The proposed system represents a formidable tool of unprecedented power to monitor the progress of different vaccination programs and - experimentally validate record-based coverage data. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - United Kingdom - - - Vaccinesurvey - - - H2020-MSCA-RISE-2014 - - - 645754 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - CHALMERS TEKNISKA HOEGSKOLA AB - UNIVERSIDAD COMPLUTENSE DE MADRID - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - - - EUR 2 036 981,25 - - - CAlcium Rechargeable BAttery Technology - - - EUR 2 036 981,25 - - - Spain - Sweden - Spain - Germany - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - "We propose calcium based rechargeable batteries to be a FET helping to solve some of the Grand Challenges our modern society is facing: pollution, oil-dependency, and climate change. Today transportation contributes to - >25% of the total CO2-emissions globally and while electrification of the sector is on-going still <1% of cars run on batteries – mainly due to issues of cost and driving ranges feasible (energy density limited). While the cost of the totally - dominant Li-ion battery (LIB) technology has been reduced by an impressive 50%(!) the last decade, LIBs are slowly reaching their fundamental limits in terms of energy density. Furthermore, the risk of limited lithium supply and associated cost - increases cannot be ignored. Therefore, new sustainable battery chemistries must be developed and Next Generation Batteries was indeed ranked as the #2 game-changing technology by the World Economic Forum in Davos 2016. - - - 2020-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-01-2016-2017 - FET-Open research and innovation actions - - - RIA - Research and Innovation action - - - Spain - - - CARBAT - - - H2020-FETOPEN-1-2016-2017 - - - 766617 - - - - - UNIVERSITA DEGLI STUDI DI PERUGIA - POLO D'INNOVAZIONE DI GENOMICA, GENETICA E BIOLOGIA SCARL - INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT - UNIVERSITA DEGLI STUDI DI MILANO - CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TECNICAS (CONICET) - CENTRO DE INVESTIGACION Y DE ESTUDIOS AVANZADOS DEL INSTITUTO POLITECNICO NACIONAL - - - EUR 738 000 - - - Harnessing Plant Reproduction for Crop Improvement - - - EUR 738 000 - - - Italy - Italy - France - Italy - Argentina - Mexico - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - - Increased crop productivity through genetic improvement of plants has significantly impacted world agriculture and the world’s population. Crop plants have followed the general pattern of introduction, selection, and - hybridization. Once introgressed, selection and breeding strategies have led to new cultivars with improved yield and adaptation. Unfortunately, many of these important traits are typically polygenic. The consequence is that only certain unique - allele combinations comply to generate elite performing genotypes. The fixation of a given genotype occurs naturally in species that display an asexual type of seed production named apomixis (i.e. clonal seed production). Unfortunately, apomixis does - not naturally occur in major crop species with few exceptions (Citrus, mango and mangosteen). In crop species, apomixis would enable the instantaneous fixation of the complete genome of the best plants. When coupled with male-sterility systems, - apomictic reproduction (with no need for male contribution) could help in addressing issues related to transgene escape from GM crops to organic or conventional crops, and thereby allow for better coexistence systems. This trait by itself is highly - valuable for agriculture, but despite many efforts it has never been possible to introduce it into the domesticated crop species of today. The financial and economic impacts of the development of apomixis technology and its application to major crops - are amazing (€1800-2300 million per annum per crop). The overall goal of the proposal is to allow for a synergy of inter-related European and international expertise to better understand the mechanisms of sexual/apomictic plant reproduction and to - facilitate the application of this increased knowledge in the development of new approaches for agriculture and food industry to increase productivity. - - 2019-01-31, ongoing project - - - 2015-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Italy - - - PROCROP - - - H2020-MSCA-RISE-2014 - - - 645674 - - - - - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - BEN-GURION UNIVERSITY OF THE NEGEV - ADVANCED WAVE SENSORS S.L. - PANEPISTIMIO KRITIS - JOBST TECHNOLOGIES GMBH - UNIVERSIDAD AUTONOMA DE MADRID - INSTITUT CURIE - - - EUR 3 411 478,75 - - - Capturing non-Amplified Tumor Circulating DNA with Ultrasound Hydrodynamics - - - EUR 3 412 478,75 - - - Greece - Israel - Spain - Greece - Germany - Spain - France - - - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - - The project suggests replacing the labor-intensive, occasionally biased and costly PCR method currently used for the detection of genetic markers with a simple, non-PCR based DNA quantification method. The suggested system - will exploit the ability of acoustic waves to probe the hydrodynamic shape of surface-bound molecules, rather than mass. The scientific challenge to be addressed is to push the limit of detection to the zM range obviating the need to use a polymerase - for DNA amplification. The technological challenge is to fabricate ultra sensitive acoustic devices and after capturing with high efficiency very low numbers of DNA present in a complex medium detecting them on the device surface. These ambitious - goals will be achieved by developing novel probes and nanoparticles of tailor-made sizes and shapes for enhanced acoustic response; exploiting high frequency acoustic devices up to the GHz range; and, employing magnetic beads with microfluidics for - specific target-capturing and enrichment. The proof-of-principle will be demonstrated during the detection of circulating-tumor DNA (ctDNA), currently an area perceived by cancer researchers as the “Holy Grail” of future cancer diagnosis, prognosis - and treatment. We intend to validate our integrated acoustic platform towards the detection of common mutations occurring in colorectal and lung cancers, i.e., KRAS, EGFR and BRAF in serum. We anticipate that the “CATCH-U-DNA” concept will set the - foundations for a simpler, more sensitive and affordable diagnostic method, from which patients in both the developed and developing countries will greatly benefit. - - 2020-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-01-2016-2017 - FET-Open research and innovation actions - - - RIA - Research and Innovation action - - - Greece - - - CATCH-U-DNA - - - H2020-FETOPEN-1-2016-2017 - - - 737212 - - - - - INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT - UNIVERSITE DE BRETAGNE OCCIDENTALE - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSITE DE NANTES - FUNDACAO GASPAR FRUTUOSO - FCIENCIAS.ID - ASSOCIACAO PARA A INVESTIGACAO E DESENVOLVIMENTO DE CIENCIAS - WAGENINGEN UNIVERSITY - UNIVERSIDAD DE SEVILLA - LEIBNIZ-ZENTRUM FUER MARINE TROPENOEKOLOGIE (ZMT) GMBH - TERRA MARIS - CREOCEAN - - - EUR 1 557 000 - - - Planning in A liquiD worlD with tropicaL StakEs: solutions from an EU-Africa-Brazil perspective - - - EUR 1 723 500 - - - France - France - France - France - Portugal - Portugal - Netherlands - Spain - Germany - France - France - - - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Marine environments are subject to growing pressures as traffic, increasing demand and changing land-use of coastal areas, seabed exploitation, dredging or mining, fishing, tourism, development of renewable energies, etc. - Sustainably managed oceans and seas can contribute to economic growth and employment, and will allow the international community to meet its global targets, including the reduction of poverty and hunger as detailed in the global 2030 Sustainable - Development Agenda. Thus, marine environments are considered opportunities for future growth not only in Europe, but also in bordering marine areas like the tropical Atlantic. - - 2021-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - France - - - PADDLE - - - H2020-MSCA-RISE-2016 - - - 734271 - - - - - CENTRE INTERNACIONAL DE METODES NUMERICS EN ENGINYERIA - - - EUR 170 121,60 - - - Towards Submarine Landslides and Their Consequences - - - EUR 170 121,60 - - - Spain - - - Research Organisations - - The last decade has witnessed a boom in offshore infrastructures, including not only oil and gas platforms and submarine pipelines due to the shift of energy exploration from onshore to offshore but also offshore wind farms, - offshore electricity grid infrastructure, and submarine communication cables and routes. This boom significantly enhances the importance of the estimation of potential submarine landslides and their consequences. It is true that submarine landslides - may have a unexpectedly long travel distance and damage infrastructure thousands of kilometers away. However numerical modelling of the entire process of submarine landslides is a long-standing challenge. In addition to constitutive models for - describing both solid-like and fluid-like behaviour of sediments, it requires also advanced numerical approaches capable of tackling extremely large deformation experienced by materials as well as interactions between structures, seawater, and - sediments. This project is motivated by these challenges and aims to develop innovative continuum models and numerical approaches for simulating submarine landslides and their consequences. A unified mixed Lagrangian finite element formulation will - be derived for handling solid mechanics (infrastructure), fluid dynamics (seawater), and poromechanics (sediments). Viscoeplastoplastic constitutive models will be developed for capturing the solid-fluid transitional behaviour of sediments. The - proposed formulation and models will be implemented on a high performance computing based numerical platform within the framework of the particle finite element method for fully coupled analyses of submarine landslides. The intended outcome is a - computational tool that can simulate the complete process of real-world submarine landslides, ranging from the initiation of failure through the sliding process to the final deposition and predicting their impact on offshore infrastructures. - - 2019-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - ToSubC - - - H2020-MSCA-IF-2016 - - - 744281 - - - - - UNIVERSITY OF GLASGOW - - - EUR 183 454,80 - - - Stressfully Transmitted Diseases: How your partner’s past stress affects your current and future health - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Early-life stress can reduce the lifespan of individuals and recent work shows that this lifespan reduction can be transmitted to reproductive partners. However, the mechanisms that allow early-life stress to damage the health - of individuals that did not experience early-life stress themselves have been little studied. - - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - STressD - - - H2020-MSCA-IF-2016 - - - 751356 - - - - - JOHN INNES CENTRE - - - EUR 183 454,80 - - - Computational Prediction and Validation of RNA thermometer at transcriptome-wide scale in living cell - - - EUR 183 454,80 - - - United Kingdom - - - Research Organisations - - Temperature is crucial to plants’ growth and development. The cold and heat stresses may drastically inhibit plant growth and cause yield losses in crops. Understanding the temperature responding mechanism is crucial to adapt - the crops to withstand extreme temperature changes caused by global warming. Among other temperature regulation mechanism, RNA thermometers (RNATs) can instantaneously respond to temperature shift and directly control translational efficiency - therefore protein abundance. To date, no RNAT has been identified in plant mainly due to the fact that instead of sequence level conservation, RNATs only have structure level conservation; also because in-vivo RNA structure probing used to be - technically challenging. The host lab has developed a powerful platform for in vivo RNA secondary structure probing at both targeted individual RNA and genome-wide scale. This proposed study aims to globally identify RNA thermometers in plants for - the first time, and to quantitatively elucidate the role of RNA structure in the post-transcriptional regulation of gene expression in response to temperature. I will measure the alteration of in vivo RNA structural features in Arabidopsis thaliana - under different temperature regime. Additionally, Ribosome profiling data and RNA-Seq data will be combined to study the translation efficiency under the corresponding temperature. Together with the identified significantly changed RNA structure - elements, we will be able to determine the putative RNAT. Finally, I will validate the predicted RNATs through studying nature variations. I will perform in-vivo RNA structure probing and determine whether the identified single nucleotide variations - (SNV) will have significant effects on temperature-regulatory elements. Besides the potential for crop improvement, our approach to globally measure RNA secondary structure and the corresponding translation efficiency will be easily applied to other - organisms and various environmental stimuli. - - 2019-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ComPreValRther - - - H2020-MSCA-IF-2016 - - - 753958 - - - - - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - - - EUR 183 454,80 - - - Global searches for dark matter and new physics with GAMBIT using effective field theory - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - "The nature of dark matter (DM) is arguably the biggest mystery in fundamental physics. Many experimental efforts are underway which aim to detect this elusive matter and measure its properties, using a wide variety of - techniques, however to make full use of this data a combined statistical analysis must be performed which makes use of the data from all these experiments simultaneously, and compares this data to the predictions of many different theories while - including all uncertainties, correlations and theoretical nuances self-consistently. Analyses of this kind are known as ""global fits"". I propose to use a newly developed, open-source global-fitting tool called GAMBIT to perform the largest and most - robust combined statistical analysis of DM data to date. To do this I will extend the capabilities of GAMBIT to allow it to work with a class of models known as ""effective theories"" which efficiently parameterise the degrees of freedom relevant to - experiments at a particular energy scale, so that a global fit can be performed in a fully model-independent way. This will require several connected layers of effective theory to be utilised, to account for the different energy scales involved in - the diverse set of DM experiments currently underway. The project is highly interdisciplinary and makes use of recent theoretical developments and experimental results in high energy physics, particle astrophysics, astronomy, nuclear physics, and - computational statistics. The proposal will generate a transfer of knowledge to the host institution while developing the candidate's theoretical expertise in new directions, particularly particle astrophysics. The results of the project will be of - wide use to the dark matter community, both in terms of direct analysis results and via the development of open-source computational tools for use in future analyses, and will provide robust guidance to experimentalists as to which dark matter - candidates are the most promising." - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - DarkGAMBIT - - - H2020-MSCA-IF-2016 - - - 752162 - - - - - UNIVERSITEIT VAN AMSTERDAM - - - EUR 165 598,80 - - - Syrian Imaginations of Europe - - - EUR 165 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Refugees’ attempts to flee to a certain country are usually preceded by imaginations about possible destination countries. These imaginations not only contribute to refugees’ decisions where to seek asylum but also have an - effect on how refugees experience realities when they eventually arrive in the destination country. The research project ‘SYRMAGINE – Syrian Imaginations of Europe’ focusses on how Europe is imagined by Syrian refugees settling in Syria’s - neighbouring countries and examines how refugees’ imaginations affect their attitudes to seek asylum in European countries. SYRMAGINE understands “geographical imaginations” of Europe as subjective human conceptions of a geographical location and - stresses the differences between “imagined regions” and reality. The project adopts an interdisciplinary mixed-method approach combining a large sample of individual surveys, semi-directive interviews and an online ethnography in two recipient and - transit countries of Syrian refugees in the Middle East, Lebanon and Turkey. - - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - SYRMAGINE - - - H2020-MSCA-IF-2016 - - - 748344 - - - - - UNIVERSITE PARIS III SORBONNE NOUVELLE - - - EUR 185 076 - - - Film Heritage and Archival Practices: Past and Present Transcontinental Encounters - - - EUR 185 076 - - - France - - - Higher or Secondary Education Establishments - - The main question that guides this research project is: what can Europe learn about its past and present film archiving and heritage practices through collections kept abroad? Focusing on Latin America, the objective of this - Fellowship is to identify how the dissemination of European film heritage informs past and present archival practices, and the understanding of both European identity and its representations. It will analyse a decade (1948–1959) of circulation of - films between both continents shaped by the creation of Cinematheques affiliated with the International Federation of Film Archives (FIAF). It will concentrate, more specifically, on the film exchanges between the Cinémathèque Française and the - Cinematheques of Argentina, Brazil and Uruguay. Nowadays, especially for younger generations, it is difficult to imagine the way films travelled in the 1950s. To gain a better understanding of why these four institutions entered this exchange - circuit, it is necessary to analyse the actual corpus, especially now that digital technologies are making these films visible again. Adopting an inter-archival and multilingual methodology, which expands cross-continentally, this Fellowship will - emphasise the transnational dimensions of film and to highlight the common connections between archival collections around the world. This innovative approach will demonstrate the value of analysing the history of exhibition abroad to review and - complement the European film histories written until now. A thorough study of these channels of European film dissemination will also help to understand past European film archiving and heritage practices in order to assist present institutional and - policy-making decisions related to film preservation, exhibition and accessibility more broadly. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - TRANSARCHIVES - - - H2020-MSCA-IF-2016 - - - 746257 - - - - - Eidgenössische Technische Hochschule Zürich - - - EUR 175 419,60 - - - Quantifying atmospheric ice nucleating particle (INP) concentrations via advances in measurement techniques and field studies of ice nucleation - - - EUR 175 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - The focal point of the research proposal is to combine the current technological advancement and scientific questions regarding the unknowns of atmospheric ice nucleation. Ice nucleation is an important pathway for cloud - formation and initiation of precipitation, therefore playing a significant role in the Earth’s hydrological cycle and energy and radiative balance. Several questions pertinent to ice nucleation remain unanswered, partially due to gaps in instrumental - technology and lack of ambient measurements. The proposed work primarily focuses on the mechanisms of ice nucleation in the atmosphere, more specifically the number, physics and chemistry of biogenic and anthropogenic aerosol particles able to act as - ice nucleating particles (INP). Field measurements with technological improvements to the existing Portable Ice Nucleation Chamber (PINC) are planned. One of the goals is to continue the time series measurements of INP parameters at the Izaña - Observatory in Tenerife, where measurements have been ongoing since 2013 by the host institution. Since the INP concentration exponentially decreases with increasing temperature, and it is the warmer sub-zero temperatures that are more relevant for - the initial ice formation in mixed-phase, the goal is to extend the measurements of INP parameters at the Izaña Observatory in Tenerife to temperatures above −30°C. Using additional instrumentation in the field, the role of mineral dust, particles of - anthropogenic origin and marine primary biogenic particles as potential INP will be investigated in more detail. From a technical perspective, the work will concentrate on lowering the detection limits of PINC and on improving its ability to - differentiate between water droplets and ice crystals. These improvements will allow measuring INP at warmer sub-zero temperatures and in immersion/condensation mode, both of which are more relevant for the first ice formation in supercooled clouds - than our current measurements. - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - ATM-METFIN - - - H2020-MSCA-IF-2016 - - - 751470 - - - - - UNIVERSIDAD DE GRANADA - - - EUR 170 121,60 - - - Soft Computing and Computer Vision for Comparative Radiography in Forensic Identification - - - EUR 170 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - There is an urgent need of providing forensic practitioners with accurate, robust, unbiased and automate identification systems. This fact makes more sense in the field of forensic anthropology due to the poor technological - development, the increasing number of mass disasters, and the unapproachable and shameful number of unidentified people in the EU. SKELETON-ID is intended to fill this technological gap by proposing a novel computer-aided automatic paradigm, which - will be implemented and validated through the development of clavicle and frontal sinus identification systems. - - 2020-03-31, Grant Agreement signed - - - 2018-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - SKELETON-ID - - - H2020-MSCA-IF-2016 - - - 746592 - - - - - UNIVERSITETET I TROMSOE - - - EUR 208 400,40 - - - Chip-based MUSICAL nanoscopy for imaging endocytosis pathways of phage viruses in liver sinusoidal endothelial cells - - - EUR 208 400,40 - - - Norway - - - Higher or Secondary Education Establishments - - Research in biology is both empowered and limited by the fluorescence imaging technology, which has witnessed a huge leap in resolution limits through super-resolved optical microscopy or also referred as optical nanoscopy. - Over the last few decades, numerous optical nanoscopy techniques have been reported for either spatial or temporal resolution enhancement. Nevertheless, the present state-of-the-art of optical nanoscopy lacks to provide high optical resolution (50 nm - or better) at high temporal resolution (~1 Hz) over large field of view (> 500 X 500 μm2) in live-cell friendly imaging conditions, such as without special buffer/fluorophores and with minimum photo-toxicity. In this proposal, the aim is to - provide ~50 nm optical resolution at significantly small temporal scales (~ seconds) in photochemical environment which is physiologically conducive for in-vivo bio-imaging applications. This is achieved by incorporating complementary knowledge and - intra-disciplinary skills on the computational nanoscopy (of the experienced researcher, ER) and chip-based optical nanoscopy technique (developed by the hosting PI). The aim is to apply Multiple Signal Classification algorithm (MUSICAL), a - computational nanoscopy algorithm developed by the experienced researcher with the fluctuating illumination provided by waveguide chip-based optical nanoscopy developed at the host university, namely Universite it Tromsø, under the ERC funded project - (Nanoscopy, PI: Ahuliwalia). The technique shall be used to image and understand endocytosis transport-highway of phages virus in liver endothelial scavenger cells. - - 2019-06-08, ongoing project - - - 2017-06-09 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Norway - - - MUSICAL - - - H2020-MSCA-IF-2016 - - - 749666 - - - - - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - - - EUR 175 419,60 - - - Game of Drones: Multimedia Streaming with Flying Terminals in Next Generation Mobile Networks - - - EUR 175 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - The use of civilian unmanned aerial vehicles (UAV) that allow capturing and streaming video in real-time is steadily increasing. One of the reasons for such interest is that the use of drones, either single units or in swarms, - is currently being considered for reconnaissance missions in emergency situations such as earthquakes, radiation leakage in nuclear power plants or in case of a terrorist attack. More challenging applications such as package delivery services are - also being considered, in which data speed, reliability and video quality are of paramount importance. Another promising application for civil UAV’s is to help providing flexibility to beyond-5G networks. The main goal of the project (highest - priority) is to study efficient adaptive video compression and streaming solutions for interactive and non-interactive omnidirectional video that allow making an efficient use of the available bandwidth while satisfying target delay and video quality - requirements. In order to deal with the limited knowledge of the interference environment at the receiver side (which is a likely scenario for airborne terminals) I will study efficient interference management and multi-user detection techniques. In - order to further optimize the bandwidth usage, the correlation between the information of different terminals (e.g., when two or more drones within a swarm are capturing partly overlapping panoramas) will be exploited, so that redundant information - is kept at the minimum necessary. The secondary goal (lower priority) of the project is the study of how to efficiently exploit the unique UAV’s mobility characteristics to provide additional coverage in congested network areas. This will be carried - out by capitalizing on the results of the main goal. In particular, the channel characterization and the interference management techniques studied in the context of video streaming will be adapted to the use of drones as 3D-mobile gap-fillers. - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - GAMODRONE - - - H2020-MSCA-IF-2016 - - - 751062 - - - - - UNIVERSIDAD AUTONOMA DE MADRID - - - EUR 170 121,60 - - - Exploiting supramolecular interactions in phthalocyanine chemistry - - - EUR 170 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - The present project aims at realizing a significant step forward in the use of noncovalent interactions as a “tool” to self-assemble phthalocyanines (Pc), planar and aromatic macrocycles which possess several unique - physicochemical properties such as an intense absorption in the red/near-infrared region of the solar spectrum, a rich redox chemistry, and a tuneable bandgap. In PhthaloSupra, the fellow will prepare stable Pc-based supramolecular polymers - self-assembled though the combination of pi-stacking, and hydrogen or halogen bonding interactions, noncovalent interactions which have never been used “simultaneously” to self-assemble in a controlled fashion Pc derivatives into supramolecular - polymers. For such ensembles, he will study some fundamental properties such as their self-assembly mechanism, light-harvesting capability, and helical chirality, all aspects that are raising nowadays a great deal of scientific attention. The - photovoltaic properties of some of the prepared architectures will also be investigated contributing to address the European and international growing interest towards reducing energy consumption through the realization of smart materials for - low-cost optoelectronic technologies. Diffusion of the PhthaloSupra achievements will be given not only to specialized researchers, but also, an importantly, to the general public in the form of several outreach activities. Undoubtedly, the - opportunity for the candidate to work in a group of the highest scientific quality such as the one of Prof. Torres, and in a highly multidisciplinary and challenging project such as PhthaloSupra will strengthen his potential to mature further to an - independent, highly trained researcher. Moreover, he will develop transferable skills, such as research management and organization, competencies which will help him to function more effectively in multidisciplinary and multicultural environments, - thus improving his career perspectives. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - PhthaloSupra - - - H2020-MSCA-IF-2016 - - - 752038 - - - - - UNIVERSIDAD AUTONOMA DE MADRID - - - EUR 158 121,60 - - - Post-crisis urban governance transformations in Southern Europe: a comparativist approach - - - EUR 158 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - The post-crisis transformations of the socio-political landscapes in Southern Europe have shaped crucial opportunities for emergent political actors and the civil society to introduce new governance mechanisms. Following a - turbulent period of social mobilizations, rapid political and institutional transformations are underway at the city, regional and national levels in countries such as Spain and Greece, and particularly in Madrid and Athens. These provide a crucial - theoretical, methodological and analytical challenge for urban studies and a key opportunity for the development of a novel relational comparative approach regarding the modifications of urban governance in Madrid and Athens. The prime research aim - of URBANiTE is to investigate the ongoing socio-political developments in the two cities, the relationship between civil society and emergent political actors and the ways these shape institutional changes. The project will produce context-sensitive, - innovative outcomes on multi-level territorial governance, of high relevance for science, society and policy, in times of sweeping challenges in Europe and beyond. Moreover, it involves integrated interdisciplinary research with policy implications - for the governance of inclusive, innovative and reflective societies, hence fully responds to challenges set out in the Horizon 2020 Societal challenges programme. The Fellowship will provide opportunity for knowledge exchange, as the fellow will - bring expertise from the UK and Greece on urban politics, citizenship and grassroots social innovation in austerity contexts. It will also allow the fellow to advance her knowledge in an interdisciplinary research environment and learn from a new - regional context, which will contribute to greater understandings of urban governance changes, social innovation and policy implementation in contemporary Europe. Lessons generated will be of wider relevance for EU- level urban governance, with - transferable outcomes to other contexts. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - URBANiTE - - - H2020-MSCA-IF-2016 - - - 747313 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 183 454,80 - - - Targeting epigenetic demethylases: development of covalent inhibitors and PROTACs (Proteolysis Targeting Chimeras). - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Epigenetics is the study of heritable changes in phenotype that does not involve changes in the underlying DNA sequence. Epigenetic modifications are partly inherited, but unlike the genome itself, are cell specific, plastic, - and its mechanisms are affected by different factors and processes such as aging, environmental factors or the use of drugs. The epigenetic changes are the result of epigenetic tags (chemical tags) that can determine gene expression. There are two - main types of epigenetic modifications: DNA methylation and histone modifications. Many diseases such as cancer, inflammation, neurological and cardiovascular diseases can be related to aberrant histone modification patterns. Since Histone - modifications are mainly carried out by three types of proteins (writers, readers and erasers) there is great therapeutic interest in these proteins, since they may influence disease onset and progression. However, the identification of potent and - selective inhibitors is challenging due to structural similarities between individual domains of the ‘epigenetic’ proteins. - - 2019-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - TEDCIP - - - H2020-MSCA-IF-2016 - - - 744389 - - - - - JOHANNES GUTENBERG-UNIVERSITAT MAINZ - - - EUR 171 460,80 - - - European Travel Writing in Context. The Socio-Political Dimension of Travelogues 1760-1850 - - - EUR 171 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - "Euopean Travel Writing in Context" investigates the thesis that travel writing is a fundamental medium in the process of the major political and social changes in Europe from the late 18th to the middle of the 19th century. - In particular, the processes of the formation of collective national identities and cultures as well as the process of the formation of the middle class with its emphasis on the individual’s identity are implicitly depicted, performed and negotiated - in travel writing of the period. - - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - EUTWIC - - - H2020-MSCA-IF-2016 - - - 751378 - - - - - ECOLE NORMALE SUPERIEURE DE LYON - - - EUR 185 076 - - - AB Initio Simulations for Super-Earths - - - EUR 185 076 - - - France - - - Higher or Secondary Education Establishments - - Since the discovery of the first exoplanet, a gaseous giant planet, two decades of an extensive planet hunt led to an amazing inventory of close-by planet systems. Among these planets a substantial number are slightly larger - than Earth but are still expected to be rocky. No similar object exists in the solar system and little is known about them. One interesting aspect is to determine the habitability of these exotic planets and if life could develop there. It is - therefore important to determine what is the structure of the deep interior of these planets and if it can generate a protecting magnetic field. - - 2019-09-03, ongoing project - - - 2017-09-04 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - France - - - ABISSE - - - H2020-MSCA-IF-2016 - - - 750901 - - - - - UNIVERSITA DEGLI STUDI ROMA TRE - - - EUR 168 277,20 - - - Polymeric Self-Assembling Units for a Controlled Adsorption and Release at the Nanoscale - - - EUR 168 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - Creating novel building blocks, which allow for an easy and large-scale fabrication of complex materials, is a challenge and a central goal of diverse scientific fields, ranging from Physics to Materials Science. - - - 2019-05-01, ongoing project - - - 2017-05-02 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - NANODRIVE - - - H2020-MSCA-IF-2016 - - - 751255 - - - - - UNIVERSITAET LEIPZIG - - - EUR 171 460,80 - - - Designing and screening two dimensional covalent organic frameworks for effective water splitting - - - EUR 171 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - In order to mitigate the energy crisis and serious environmental pollution as well as global warming, the conversion of solar energy into chemical fuels including hydrogen has been extensively developed to flexibly and - conveniently utilize this clean energy form. Generally, hydrogen can be produced via photocatalytic water splitting under sunlight irradiation. The efficiency of this solar driven process to synthesize hydrogen depends entirely on the selected - semiconducting photocatalysts. - - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - 2D-COF-WS - - - H2020-MSCA-IF-2016 - - - 751848 - - - - - MUSEUM NATIONAL D'HISTOIRE NATURELLE - UNIVERSITAT AUTONOMA DE BARCELONA - CERDAN INGENIEROS S.L. - MARTIN LOYER - UNIVERSITE D'AIX MARSEILLE - UNIVERSITE D'AVIGNON ET DES PAYS DE VAUCLUSE - UNIVERSITE PARIS DIDEROT - PARIS 7 - UNIVERSITE PARIS III SORBONNE NOUVELLE - CABILDO INSULAR DE LANZAROTE - ASSOCIACIO GEOPARC CONCA DE TREMP -MONTSEC - - - EUR 1 296 000 - - - Geoparks: Heritage, Education and Sustainable Development - an Innovative Methodology for Southern Countries. Case Study in Morocco (Atlas Mountains, Marrakech) - - - EUR 1 296 000 - - - France - Spain - Spain - France - France - France - France - France - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Other - - According to the Charter of the European Geoparks Network adopted in Greece the 5th June of 2000, a European Geopark “is a territory which includes a particular geological heritage and a sustainable territorial development - strategy supported by a European programme to promote development. […]”.These territories have been labelled regarding their geological, cultural and ecological heritage - since the early 2000s this Label knows a growing success among European - countries, particularly in the West (France, Germany, Italy, Spain). In 2013, 54 European Geoparks received the precious label. This international recognition by UNESCO attracts Southern countries to implement development strategies in line with the - recommendations of good-practices management oriented by international organizations. Indeed, UNESCO takes into account a plurality of selective criteria such as a remarkable heritage (geology, archaeology, biodiversity, cultural), citizen - participation, sustainable regional economic development plan, heritage and socio-economic values for local populations, etc. to proceed to the inscription process. It is based on an integrated and sustainable management & conservation strategy - of natural and cultural heritage from an interdisciplinary approach (Humanities and Life & Earth Sciences) in consultation with local stakeholders (local communities, universities and civil society). Currently, there is no “Geopark methodology” - adapted to the South. Thus, the GEOPARK project aims to study potential and compared areas (EU/Africa) with remarkable geological, ecological, social and cultural heritage. One located in Central Catalunia (Spain) and the other in the Zat Valley - (Morocco) - Marrakech. Endowed with varied skills in Humanities and Life and Earth Sciences, GEOPARK project partners (public, private) propose to study biodiversity, geology, prehistory, social aspects, heritage, tourism as a geopark based on - empirical surveys, field collecting data and shared experience. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - France - - - Geopark - - - H2020-MSCA-RISE-2014 - - - 644015 - - - - - RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN - RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN - - - EUR 1 973 875 - - - Search for Higgs bosons decaying to charm quarks - - - EUR 1 973 875 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In the standard model of particle physics (SM), the Higgs boson explains the existence of mass of the elementary particles. However, the model suffers from severe weaknesses: radiative corrections drive the theoretical mass of - the Higgs boson to extremely high, unnatural values, while the observed mass is rather low (the famous hierarchy problem). Unknown mechanisms of physics beyond the standard model (BSM) must exist to avoid this unnatural situation. Such BSM mechanisms - modify the predicted properties and decay patterns of the Higgs boson. The experimental collaborations at the LHC are measuring these decay patterns as precisely as possible. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - HIGCC - - - ERC-2016-COG - - - 724704 - - - - - Eidgenössische Technische Hochschule Zürich - Eidgenössische Technische Hochschule Zürich - - - EUR 143 750 - - - Automated detection of damage to buildings - - - EUR 143 750 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Hail and storm damages represent the most often occurring cases for building insurance companies. Currently, the damage is estimated by an insurance expert, visiting the damaged building and drafting a report. Researchers at - the Computer Vision Lab at ETH Zurich joined forces with business and sales people, spinning out the company Casalva, to strongly reduce such costs via automated image analysis. The idea is that the insurers’ clients upload photos of the damages, - which will then be analyzed automatically by a computer. This involves computer vision technologies – grounded in the ERC project VarCity – to recognize the damaged building structures and to analyze the corresponding textures as to assess the extent - of the damage and the estimated costs for its repair. Cutting costs is not the only consideration, as the fast assessment of damages improves customer satisfaction and prevents the occurrence of additional damages because of a delayed repair (like - water leaking before repair). Such follow-on damages are estimated to be 20% of overall costs on average and are therefore far from negligible. Guaranteeing a short term response currently is a major issue, as a single storm may affect thousands of - buildings. Processing times tend to stretch out due to the peak in cases following such extreme weather events. Over half of hail storm damage cases concern facade structures. The VarCity project produced methods to automatically parse facades into - such structures, and to select the best way to describe their textures. These will be refined to optimally deal with the application area. The remaining technical developments and risk mitigations will be funded through other means (a Swiss project - that has already been submitted), while this Proof-of-Concept project will focus on equally important aspects like market analysis, development of a corporate identity and graphical house style for the Casalva spin-off, that has been created but - should now get market introduction. - - 2018-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Switzerland - - - ADDABU - - - ERC-2017-PoC - - - 768610 - - - - - WEIZMANN INSTITUTE OF SCIENCE - WEIZMANN INSTITUTE OF SCIENCE - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 2 499 944 - - - Lubricating Cartilage: exploring the relation between lubrication and gene-regulation to alleviate osteoarthritis - - - EUR 2 499 944 - - - Israel - Israel - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Can we exploit insights from the remarkably lubricated surfaces of articular cartilage, to create lubricants that may alleviate osteoarthritis (OA), the most widespread joint disease, affecting millions? These, succinctly, are - the challenges of the present proposal. They are driven by our recent finding that lubrication of destabilised joints leads to changes in gene-regulation of the cartilage-embedded chondrocytes to protect against development of the disease. OA - alleviation is known to arise through orthopedically suppressing shear-stresses on the cartilage, and a central premise of this project is that, by reducing friction at the articulating cartilage through suitable lubrication, we may achieve the same - beneficial effect on the disease. The objectives of this project are to better understand the origins of cartilage boundary lubrication through examination of friction-reduction by its main molecular components, and exploit that understanding to - create lubricants that, on intra-articular injection, will lubricate cartilage sufficiently well to achieve alleviation of OA via gene regulation. The project will examine, via both nanotribometric and macroscopic measurements, how the main molecular - species implicated in cartilage lubrication, lipids, hyaluronan and lubricin, and their combinations, act together to form optimally lubricating boundary layers on model surfaces as well as on excised cartilage. Based on this, we shall develop - suitable materials to lubricate cartilage in joints, using mouse models. Lubricants will further be optimized with respect to their retention in the joint and cartilage targeting, both in model studies and in vivo. The effect of the lubricants in - regulating gene expression, in reducing pain and cartilage degradation, and in promoting stem-cell adhesion to the cartilage will be studied in a mouse model in which OA has been induced. Our results will have implications for treatment of a common, - debilitating disease. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Israel - - - CartiLube - - - ERC-2016-ADG - - - 743016 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 2 499 513,85 - - - Evolution of regulatory landscapes at multiple timescales - - - EUR 2 499 513,85 - - - Spain - Spain - - - Research Organisations - Research Organisations - - Evolution of animal morphology relies on changes in developmental programs that control body plans and organ shape. Such changes are thought to arise form alteration of the expression of functionally conserved developmental - genes and their vast downstream networks. Although this hypothesis has a profound impact on the way we view animal evolution, final proof is still lacking. The hypothesis calls for evolution to take place mainly through modifications of - cis-regulatory elements (CREs) controlling gene expression. However, these genomic regions are precisely those that we understand the least and, until recently, basic knowledge on how regulatory information is organized in the 3D genome or how to - spatio-temporally assign CREs to their target genes was unknown. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Spain - - - Evoland - - - ERC-2016-ADG - - - 740041 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 1 979 112 - - - Climate dimension of natural halogens in the Earth system: Past, present, future - - - EUR 1 979 112 - - - Spain - Spain - - - Research Organisations - Research Organisations - - Naturally-emitted very short-lived halogens (VSLH) have a profound impact on the chemistry and composition of the atmosphere, destroying greenhouse gases and altering aerosol production, which together can change the Earth's - radiative balance. Therefore, natural halogens possess leverage to influence climate, although their contribution to climate change is not well established and most climate models have yet to consider their effects. Also, there is increasing evidence - that natural halogens i) impact on the air quality of coastal cities, ii) accelerates the atmospheric deposition of mercury (a toxic heavy metal) and iii) that their natural ocean and ice emissions are controlled by biological and photochemical - mechanisms that may respond to climate changes. Motivated by the above, this project aims to quantify the so far unrecognized natural halogen-climate feedbacks and the impact of these feedbacks on global atmospheric oxidizing capacity (AOC) and - radiative forcing (RF) across pre-industrial, present and future climates. Answering these questions is essential to predict if these climate-mediated feedbacks can reduce or amplify future climate change. To this end we will develop a - multidisciplinary research approach using laboratory and field observations and models interactively that will allow us to peel apart the detailed physical processes behind the contribution of natural halogens to global climate change. Furthermore, - the work plan also involves examining past-future climate impacts of natural halogens within a holistic Earth System model, where we will develop the multidirectional halogen interactions in the land-ocean-ice-biosphere-atmosphere coupled system. - This will provide a breakthrough in our understanding of the importance of these natural processes for the composition and oxidation capacity of the Earth's atmosphere and climate, both in the presence and absence of human influence. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Spain - - - CLIMAHAL - - - ERC-2016-COG - - - 726349 - - - - - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - - - EUR 2 069 000 - - - Molecular Biology of Nascent Chains: Co-translational folding and assembly of proteins in eukaryotes - - - EUR 2 069 000 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Biological activity of cells depends on timely production of natively folded proteins by powerful translation and folding machineries. At a critical regulatory intersection of translation and folding, ribosomes act as - integration hubs coordinating chaperone, enzyme and membrane targeting factor activity, and mRNA coding sequence specifies local changes in translation speed, influencing folding. Final assembly of proteins into oligomeric complexes however, has long - been considered posttranslational and dependent on random collision of fully synthesized diffusing subunits. In a shift of paradigm our recent evidence now suggests that in bacteria, assembly initiates co-translationally assisted by chaperones, and - gene organization into operons drives co-localized translation of complex subunits that impacts efficiency of assembly. Fundamental differences in eukaryotes such as rarity of operons and differing chaperone constellations imply a widely different - folding and assembly biology, which remains largely unexplored. Our development of the selective ribosome profiling (SeRP) method now allows ground-breaking identification and definition of dynamic interactions of nascent chains, at near-residue - resolution. Using SeRP with supporting biochemistry and microscopy, we will unravel the nascent chain molecular biology underpinning protein folding and assembly in yeast. Specifically, we will establish (1) basic features and prevalence of - co-translational protein assembly, (2) how chaperones guide co-translational protein folding to affect assembly, (3) whether translation of subunit-encoding mRNAs is spatially organized, and if so, how this occurs, and (4) to what extent translation - speed variations affect assembly. Subunit interaction profiles complemented by mRNA localization will expose the timing and interplay of protein folding and assembly steps linked to protein synthesis, establishing a detailed conceptually new biology - of complex assembly in eukaryotes. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - TransFold - - - ERC-2016-ADG - - - 743118 - - - - - THE UNIVERSITY OF HUDDERSFIELD - THE UNIVERSITY OF HUDDERSFIELD - BATH SPA UNIVERSITY - INSTITUT DE RECHERCHE ET DE COORDINATION ACOUSTIQUE MUSIQUE - IRCAM - UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK - - - EUR 2 471 416 - - - Interactive Research in Music as Sound:Transforming Digital Musicology - - - EUR 2 471 416 - - - United Kingdom - United Kingdom - United Kingdom - France - Ireland - - - Higher or Secondary Education Establishments - Denise Ogden - Tel.: +44-1484-473192 - Fax: +44-1484-472682 - Higher or Secondary Education Establishments - Denise Ogden - Tel.: +44-1484-473192 - Fax: +44-1484-472682 - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - - In an age when technology is revolutionizing the ways in which music is made and distributed, this project proposes correspondingly to transform approaches to musicology, moving from a primarily fixed, text-based approach to - one that incorporates as an integral feature the interactive and aural. It brings skills and expertise from music technology to assist in the development of research strategies and software to enable musicological research to engage more directly - with sound. It will pioneer a ground-breaking approach to music research in which dynamic interaction with sound is fundamental and music’s temporal and transient nature are central to research investigations and their dissemination, presenting a - significant conceptual challenge to the traditional textual bias of much musical research and leading to new enhanced modes of musicological knowledge. Unlike current Digital Musicology, rather than using software primarily to extract quantized data, - IRiMaS facilitates research through dynamic interactive engagement with sound. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - IRiMaS - - - ERC-2016-ADG - - - 741904 - - - - - UNIVERSITEIT UTRECHT - UNIVERSITEIT UTRECHT - CITY UNIVERSITY OF LONDON - - - EUR 2 494 278,75 - - - Forests and Trees: the Formal Semantics of Collective Categorization - - - EUR 2 494 278,75 - - - Netherlands - Netherlands - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Languages have various ways of referring to collections like families, herds and forests. The grammatical properties of collective expressions critically determine how we understand them. The sentences “this forest is old” and - “these trees are old” categorize an arboreal collection using a concept (“old”), while conveying different meanings. This semantic difference correlates with the difference in grammatical number between the sentences: singular vs. plural. Such - effects of collective categorization in language are crucial for understanding the connections between grammar and the mind, as well as for artificial intelligence. However, currently little is known about the mechanisms underlying our linguistic - ability to conceptualize collections. This project aims to develop a novel linguistic theory of this ability, applied to a wide range of empirical phenomena and interdisciplinary challenges in computational semantics and comparative linguistics, - benefiting from the recent synergy between linguistics and the psychology of concepts. The idea is that when classifying a collection, speakers rely on two inferential principles with mental concepts: (i) geometric inferences: a forest is considered - “far away” if all of its trees are far; (ii) symmetric inferences: two trees are “similar” if each of them is similar to the other. The leading hypothesis is that uniform interactions between these inferential principles and the grammar of collective - expressions account for collective categorization in language. This hypothesis is explored in three work packages, each of which develops the semantic theory and evaluates it on a different interdisciplinary domain: human interaction with geographic - information systems, behavioral linguistic experiments, and comparative linguistics. Together, the three components of the project are expected to lead to a theoretical breakthrough in semantic theory and to enrich its interdisciplinary connections - with neighboring disciplines. - - 2022-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Netherlands - - - ROCKY - - - ERC-2016-ADG - - - 742204 - - - - - UNIVERSITEIT ANTWERPEN - UNIVERSITEIT ANTWERPEN - - - EUR 149 687,50 - - - Development of a policy to stop the suffering caused by Nodding Syndrome andOnchocerciasis associated epilepsy - - - EUR 149 687,50 - - - Belgium - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Nodding syndrome (NS) is a form of epilepsy characterized by head-nodding, often associated with severe intellectual disability, psychiatric problems and early death. Initially, NS was reported only in onchocerciasis-endemic - regions in Tanzania, Uganda and South Sudan. Until recently, the cause of the syndrome was unknown. Therefore, no strategy for prevention and cure was possible. Our ERC project (NSETHIO) discovered that NS is only one of the clinical presentations of - onchocerciasis associated epilepsy (OAE) and that this form of epilepsy is probably present in all onchocerciasis endemic regions where onchocerciasis is insufficiently controlled. We estimate that the number of excess cases of epilepsy due to - onchocerciasis could be as much as 100,000. Based on NSETHIO findings we will develop an innovative comprehensive OAE policy plan that will prevent children from developing OAE and that will reduce the negative consequences of OAE for the economy and - society. This plan includes the following components: strengthening community directed ivermectin (IVM) treatment programs (IVM will stop OAE), establishing an SMS based epilepsy surveillance system by epilepsy trained community-directed IVM - distributors, developing a community-based care system using evidence based OAE treatment algorithms and a community-awareness program. We will fine tune the plan during 2 OAE stakeholder workshops, field test it in a high OAE prevalence health zone - and calculate its cost. We will create an international OAE alliance including scientists and health care workers, representatives of communities and advocacy groups, WHO, Ministries of Health, non-governmental organizations, the pharmaceutical - industry and donors to scale up the implementation of these interventions after the end of the NSstop project. Reducing the burden of disease caused by OAE will have great positive cultural, societal and economic impacts on affected families and - villages in many parts of Africa. - - 2019-02-28, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Belgium - - - NSstop - - - ERC-2017-PoC - - - 768815 - - - - - FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION - FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION - - - EUR 2 495 838,75 - - - Connectivity, plasticity and function of an olfactory memory circuit - - - EUR 2 495 838,75 - - - Switzerland - Switzerland - - - Research Organisations - Research Organisations - - The brain accumulates knowledge by experience-driven modifications of neuronal connectivity and creates models of the world that enable intelligent behavior. It is thought that these processes are based on autoassociative - mechanisms of circuit plasticity. However, direct tests of these fundamental concepts are difficult because they require dense reconstructions of neuronal wiring diagrams. We will dissect structural and functional mechanisms of autoassociative memory - in telencephalic area Dp of adult zebrafish, the homologue of olfactory cortex. The small size of the zebrafish brain provides essential advantages for exhaustive measurements of neuronal activity and connectivity patterns. Key predictions of - theoretical models will be examined by analyzing effects of odor discrimination learning on the dynamics and stability of odor representations in Dp. The underlying structural circuit modifications will be examined in the same brains by circuit - reconstruction using serial block face scanning electron microscopy (SBEM). The dense reconstruction of neuronal ensembles responding to learned and novel odors will allow for advanced analyses of structure-function relationships that have not been - possible so far. Odor stimulation in a virtual environment will be combined with optogenetic activation or silencing of neuromodulatory inputs to write and disrupt specific olfactory memories and to analyze the effects on behavior and connectivity. - The underlying cellular mechanisms of synaptic plasticity and metaplasticity will be examined by electrophysiology, imaging and optogenetic approaches. Mutants will be used to assess effects of disease-related mutations on circuit structure, function - and plasticity. These mechanistic analyses are guided by theoretical models, expected to generate direct insights into elementary computations underlying higher brain functions, and likely to uncover causal links between circuit connectivity, circuit - function and behavior. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Switzerland - - - MCircuits - - - ERC-2016-ADG - - - 742576 - - - - - UNIVERSIDAD AUTONOMA DE MADRID - UNIVERSIDAD AUTONOMA DE MADRID - - - EUR 1 499 500 - - - Modification of Molecular structure Under Strong Coupling to confined Light modES - - - EUR 1 499 500 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Understanding and controlling the properties of matter is one of the overarching goals of modern science. A powerful way to achieve is this by using light, usually in the form of intense laser beams. However, modern advances - in nanophotonics allow us to confine light modes so strongly that their effect on matter is felt even when no external fields are present. In this regime of “strong coupling” or “vacuum Rabi splitting”, the fundamental excitations of the coupled - system are hybrid light-matter states which combine the properties of both constituents, so-called polaritons. Little attention has been paid to the fact that strong coupling can also affect internal structure, such as nuclear motion in molecules. - First experimental indications for this effect have been found, but current theory cannot explain or predict such changes. We will thus develop theoretical methods that can treat the modification of molecular structure under strong coupling to - confined light modes. This will require advances in the microscopic description of the molecules under strong coupling by explicitly including their rovibrational degrees of freedom, as well as techniques to incorporate the influence of these modes - in the macroscopic setting of collective strong coupling. In order to achieve this, we will adapt well-known techniques from quantum chemistry and combine them with the concepts of polariton physics. We will investigate what level of control can be - gained through this approach, and whether confined light modes could act as a “photonic catalyst” to control molecular dynamics without requiring an active ingredient. This could present a novel tool to control photochemical reactions that are of - paramount importance in the biological mechanisms of vision and photosynthesis, and hold great interest for use in memories, photoswitching devices, light-driven actuators, or solar energy storage. Consequently, this work could have wide-ranging - impact on many different fields of science. - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Spain - - - MMUSCLES - - - ERC-2016-STG - - - 714870 - - - - - UNIVERSIDAD AUTONOMA DE MADRID - UNIVERSIDAD AUTONOMA DE MADRID - - - EUR 149 975 - - - Complementary Adhesive Coatings based on Molecular Association - - - EUR 149 975 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Adhesives constitute a potent and very broad technology, offering innovative solutions to a wide range of industries and providing craftsmen and private consumers with easy-to-use technically-advanced products. For every - application in which two elements need to be fastened together, a specific adhesive can in principle be formulated. - - - 2018-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Spain - - - CompAd - - - ERC-2016-PoC - - - 754795 - - - - - UNIVERSITY OF DURHAM - UNIVERSIDAD AUTONOMA DE MADRID - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - UNIVERSITEIT LEIDEN - THE UNIVERSITY OF NOTTINGHAM - FUNDACION CENTRO DE ESTUDIOS DE FISICA DEL COSMOS DE ARAGON - RIJKSUNIVERSITEIT GRONINGEN - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - HITS GGMBH - ISTITUTO NAZIONALE DI ASTROFISICA - - - EUR 1 350 000 - - - Latin American Chinese European Galaxy Formation Network - - - EUR 1 561 500 - - - United Kingdom - Spain - Germany - Netherlands - United Kingdom - Spain - Netherlands - Spain - Germany - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - - Spectacular breakthroughs in astronomy have been driven by a combination of observational advances and groundbreaking computer simulations. Simulations are now accepted as being essential for the interpretation and - exploitation of data. Europe is a world leader in this area. Our aim is to build on the highly successful FP7 LACEGAL IRSES to avoid fragmentation of expertise and concentration of supercomputer resources in a few groups. The expansion of LACEGAL - will build new research collaborations between Europe and the main centres in Latin America and China, and enhance those established under IRSES. The bulk of exchanges will be undertaken by Early Stage Researchers, who will gain access to unique - training in high performance computing, equipping them with skills which are much sought after in academia and industry. We also plan network-wide workshops to share knowledge and provide specialized training, disseminating project results and - expertise beyond the membership of LACEGAL. Our research program addresses key questions in galaxy formation and the large-scale structure of the Universe. An important goal is to produce the multi-wavelength theoretical models which are urgently - needed to meet the challenge posed by upcoming observations. LACEGAL is particularly timely as it will allow us to analyse new data and to prepare for major international projects in which LACEGAL scientists have leadership: 1) The Dark Energy - Survey, 2) the European Space Agency's Gaia mission, 3) The Atacama Large Millimetre Array. 4) The Dark Energy Spectroscopic Instrument survey, 5) The PAU Camera Survey, 6) The Javalambra Survey, 7) ESA’s Euclid mission, 8) The Large Synoptic Survey - Telescope, 9) The Square Kilometre Array. LACEGAL will help Europe to play a leading role in the breakthroughs expected from these major international projects. - - 2021-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - United Kingdom - - - LACEGAL - - - H2020-MSCA-RISE-2016 - - - 734374 - - - - - DESCUBRE - FUNDACION ANDALUZA PARA LA DIVULGACION DE LA INNOVACION Y EL CONOCIMIENTO - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - UNIVERSIDAD DE ALMERIA - UNIVERSIDAD DE CADIZ - UNIVERSIDAD DE CORDOBA - UNIVERSIDAD DE GRANADA - UNIVERSIDAD DE HUELVA - UNIVERSIDAD DE JAEN - UNIVERSIDAD DE MALAGA - UNIVERSIDAD DE SEVILLA - UNIVERSIDAD PABLO DE OLAVIDE - Fundacion Publica Andaluza Progreso y Salud - INSTITUTO MUNICIPAL DE GESTION MEDIOAMBIENTAL - JARDIN BOTANICO DE CORDOBA - - - EUR 174 782,82 - - - Open Researchers - - - EUR 368 010,16 - - - Spain - Spain - Spain - Spain - Spain - Spain - Spain - Spain - Spain - Spain - Spain - Spain - Spain - - - Other - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - ‘Open Researchers’ is the fifth experience of Andalusia in the European Researchers’ Night. The project is designed to increase the awareness of research as a solution to the numerous challenges faced by citizens all around - the world and mainly in Europe. The idea of the project, ‘The future is today: understandable ground-breaking science for a better living’, has been conceived in a time of change, a moment where becomes clearer that we must join efforts to find - sustainable, equal, innovative and creative solutions to give answer to the societal challenges. To this end, according to the RRI, it is essential to promote young people’s interest in Science and Research by opening it to general public through its - main protagonists, researchers. - - 2017-11-30, closed project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.5."> - - - MSCA-NIGHT-2016 - European Researchers' Night - - - CSA - Coordination and support action - - - Spain - - - OPENRESEARCHERS - - - H2020-MSCA-NIGHT-2016 - - - 722930 - - - - - UNIVERSIDAD AUTONOMA DE MADRID - UNIVERSIDAD AUTONOMA DE MADRID - - - EUR 1 750 625 - - - A bottom-up topological superconductor based on quantum dot arrays - - - EUR 1 750 625 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The realization of a topological superconductor (TS) and of Majorana fermion (MF) quasiparticles promises to open new avenues towards decoherence-robust topological quantum computing. However, further developments in this - direction, including the investigation of their topological properties, have been hindered by the lack of a fully conclusive demonstration. In setups based on 1D nanostructures, e.g. semiconductor nanowires and magnetic adatom chains, this is linked - to the difficulty to unambiguously assign the main reported signatures, a zero-bias peak in Andreev conductance, to MF modes. This proposal aims to overcome these limitations by exploring an alternative approach in which a 1D TS is built from the - bottom up. In particular, arrays of proximity-coupled semiconductor quantum dots (QDs) will be explored as a platform for emulating the Kitaev chain. Such an approach offers the advantage that the evolution of subgap states into MF modes is followed - during the assembly of the TS, thereby providing conclusive evidence of their realization. It also enables to controllably adjust the chain parameters to their optimal values where the topological array is most robust. - - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Spain - - - TOPOQDot - - - ERC-2016-STG - - - 716559 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - TTY-SAATIO - ECOLE SUPERIEURE DE PHYSIQUE ET DECHIMIE INDUSTRIELLES DE LA VILLE DEPARIS - UNIVERSITEIT TWENTE - AIRBUS DEFENCE AND SPACE GMBH - DTNW OFFENTLICHE PRUFSTELLE GMBH - MILLIDYNE OY - UNIVERSITAT ZURICH - - - EUR 3 901 820,76 - - - Lubricant impregnated slippery surfaces - - - EUR 3 901 820,76 - - - Germany - United Kingdom - Finland - France - Netherlands - Germany - Germany - Finland - Switzerland - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - LubISS, Lubricant Impregnated Slippery Surfaces, is the first European Training Network with the main objectives of designing, characterizing, and modelling low adhesive easy-to-clean surfaces for anti-icing and anti-fouling. - In a coordinated effort among 9 world-class academic institutions and industrial partners from 6 European countries (Finland, France, Germany, Great Britain, Netherlands, Switzerland), advanced lubricant impregnated surfaces will be developed. - Drawing upon the distinguished expertise within the consortium, textured surfaces impregnated with a lubricating liquid or gel will be designed and fabricated through modern experimental preparation, multi-scale characterization methods, and high - power simulation tools. With these broad capabilities, the LubISS network offers a unique training platform for Early Stage Researchers (ESRs) in a multidisciplinary research endeavor of great technological, industrial and environmental importance. - The recently introduced concept of lubricant impregnated surfaces is a promising approach to reduce the adhesion of ice as well as biofilm-forming bacteria-to-surfaces. To achieve societal impact, understanding the intimate relationships between the - impregnating lubricant, the surface topography, and the adhesion of ice, bacteria, or other biofouling microorganisms is critical. The general aim of this ITN is two-fold: 1) to establish a fundamental understanding between these relationships - through academic and industrial collaborations in physics, chemistry, biomedicine, materials science and engineering, and 2) to educate and train young researchers in this vital area of technology. The LubISS network will investigate many aspects of - lubricant impregnated surfaces, including the optimization of the lubricant stability under static and dynamic flow conditions, methods for replenishing the lubricant for long-term applications, and benchmarking against state-of-the-art surfaces. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - LubISS - - - H2020-MSCA-ITN-2016 - - - 722497 - - - - - INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSITE DE NANTES - BATH SPA UNIVERSITY - THE UNIVERSITY OF BIRMINGHAM - Faculdade de letras da Universidade de Lisboa - UNIVERSITAET HAMBURG - - - EUR 1 107 000 - - - Slavery in Africa: a dialogue between Europe and Africa - - - EUR 1 107 000 - - - France - France - France - United Kingdom - United Kingdom - Portugal - Germany - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The overall objective of the project is to establish a top-level scientific network of several institutions and research groups from Europe and Africa on the field of slavery studies. It aims at focusing mutual efforts of 13 - partners with extended and complementary competences in their respective research fields and at gathering multidisciplinary expertise in slavery-related issues by encouraging the exchange of young and senior researchers from both continents. - - 2020-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - France - - - SLAFNET - - - H2020-MSCA-RISE-2016 - - - 734596 - - - - - UNIVERSITAT POLITECNICA DE CATALUNYA - UNIVERSIDAD DE ALCALA - UNIVERSIDAD DE SEVILLA - UNIVERSIDAD DE ZARAGOZA - TECHNISCHE UNIVERSITAET GRAZ - UNIVERSITE LIBRE DE BRUXELLES - UNIVERSITA DEGLI STUDI ROMA TRE - USTAV INFORMATIKY AV CR - CENTRO DE INVESTIGACION Y DE ESTUDIOS AVANZADOS DEL INSTITUTO POLITECNICO NACIONAL - UNIVERSIDAD NACIONAL AUTONOMA DE MEXICO - CENTRO DE INVESTIGACION EN MATEMATICAS AC - UNIVERSIDAD AUTONOMA DE SAN LUIS POTOSI - CARLETON UNIVERSITY - UNIVERSIDAD DE SANTIAGO DE CHILE - - - EUR 324 000 - - - Combinatorics of Networks and Computation - - - EUR 382 500 - - - Spain - Spain - Spain - Spain - Austria - Belgium - Italy - Czech Republic - Mexico - Mexico - Mexico - Mexico - Canada - Chile - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - "Networks are present in our lives in numerous different environments: to name just a few, networks can model social relationships, they can model the Internet and links between web pages, they might model the spread of a - virus infection between people, and they might represent computer processors/sensors that have to exchange information. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Spain - - - CONNECT - - - H2020-MSCA-RISE-2016 - - - 734922 - - - - - UNIVERSIDAD AUTONOMA DE MADRID - UNIVERSIDAD AUTONOMA DE MADRID - - - EUR 1 498 625 - - - Endolysosomal-mitochondria crosstalk in cell and organism homeostasis - - - EUR 1 498 625 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - For many years, mitochondria were viewed as semiautonomous organelles, required only for cellular energetics. This view has been displaced by the concept that mitochondria are fully integrated into the life of the cell and - that mitochondrial function and stress response rapidly affect other organelles, and even other tissues. A recent discovery from my lab demonstrated that mitochondrial metabolism regulates lysosomal degradation (Cell Metabolism, 2015), thus opening - the way to investigate the mechanism behind communication between these organelles and its consequences for homeostasis. With this proposal, we want to assess how mitochondrial crosstalk with endolysosomal compartment controls cellular homeostasis - and how mitochondrial dysfunction in certain tissues may account for systemic effects on the rest of the organism. EndoMitTalk will deliver significant breakthroughs on (1) the molecular mediators of endolysosomal-mitochondria communication, and how - deregulation of this crosstalk alters cellular (2), and organism homeostasis (3). Our central goals are: 1a,b. To identify metabolic and physical connections mediating endolysosomal-mitochondria crosstalk; 2a. To decode the consequences of altered - interorganelle communication in cellular homeostasis 2b. To study the therapeutic potential of improving lysosomal function in respiration-deficient cells; 3a. To assess how unresolved organelle dysfunction and metabolic stresses exclusively in - immune cells affects organism homeostasis and lifespan. 3b. To decipher the molecular mediators by which organelle dysfunction in T cells contributes to age-associated diseases, with special focus in cardiorenal and metabolic syndromes. In sum, - EndoMitTalk puts forward an ambitious and multidisciplinary but feasible program with the wide purpose of understanding and improving clinical interventions in mitochondrial diseases and age-related pathologies. - - 2022-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Spain - - - EndoMitTalk - - - ERC-2016-STG - - - 715322 - - - - - UNIVERSITAT ZURICH - UNIVERSITAT ZURICH - - - EUR 2 500 000 - - - GeoViSense: Towards a transdisciplinary human sensor science of human visuo-spatial decision making with geographic information displays - - - EUR 2 500 000 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Well-designed mobile, human responsive geographic information technology could improve the lives of millions who daily need to make time critical and societally relevant decisions on the go. However, what are the basic - processes with which humans make visuo-spatial decisions when guided by responsive geographic information displays? Visualization research todate has been driven by technical and computational advances to overcome data deluges, but we still have a - poor understanding whether, how, and when visual displays support spatio-temporal decision making and action, and for which kinds of users. We will break new ground to overcome this transdisciplinary knowledge gap and aim to: (1) integrate fragmented - human-visualization-environment research across the sciences including natural, social/behavioral, and the engineering sciences, all critical to tackle this interdisciplinary problem, (2) develop missing, empirically evaluated design guidelines for - human-computer interfaces of current/emerging mobile geographic information technology to support affective, effective, and efficient spatio-temporal decision-making, (3) develop unconventional evaluation methods by critical examination of how - perceptual, cognitive, psycho-physiological, and display design factors might influence visuo-spatio-temporal decision making across broad ranges of users and mobile use contexts, and (4) scale up empirical methods from to-date controlled behavioral - lab paradigms towards a new in-situ mobile human sensor science. A paradigm shift from current lab-based neuro-cognitive and affective science towards a location-based, close human sensing science will radically change the way we study human behavior - across science. In doing so, we can improve spatio-temporal every-day decision making with graphic displays, and facilitate sustainable solutions for the increasingly mobile digital information society having to mitigate environmental emergencies, - human refugee crises, or terror attacks. - - 2022-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Switzerland - - - GeoViSense - - - ERC-2016-ADG - - - 740426 - - - - - LOUGHBOROUGH UNIVERSITY - UNIVERSITAT DE BARCELONA - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSITE D'AIX MARSEILLE - UNIVERSIDAD POLITECNICA DE MADRID - UNIVERSIDAD AUTONOMA DE MADRID - UNIVERSITAET STUTTGART - - - EUR 526 500 - - - Stability and Transitions in Physical Processes - - - EUR 711 000 - - - United Kingdom - Spain - France - France - Spain - Spain - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Many dynamical processes in natural sciences are organized by invariant objects that behave in rather simple ways under time evolution, such as equilibria, periodic orbits, or higher-dimensional invariant surfaces. These - objects and the invariant manifolds attached to them act as landmarks that organize the behavior of other trajectories and yield a qualitative description of the dynamics. By computing strategically chosen landmarks, one can obtain considerable - information of the possible behaviors of the system. - - 2021-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - United Kingdom - - - TraX - - - H2020-MSCA-RISE-2016 - - - 734557 - - - - - HELMHOLTZ-ZENTRUM FUER UMWELTFORSCHUNG GMBH - UFZ - UMWELTBUNDESAMT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (UBA GMBH) - HELSINGIN YLIOPISTO - FORSCHUNGSZENTRUM JULICH GMBH - NATURAL ENVIRONMENT RESEARCH COUNCIL - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - SUOMEN YMPARISTOKESKUS - SENCKENBERG GESELLSCHAFT FUR NATURFORSCHUNG - MAGYAR TUDOMANYOS AKADEMIA OKOLOGIAI KUTATOKOZPONT - CONSIGLIO NAZIONALE DELLE RICERCHE - FUNDACAO DA FACULDADE DE CIENCIAS DA UNIVERSIDADE DE LISBOA FP - UNIVERSIDAD DE GRANADA - EIGEN VERMOGEN VAN HET INSTITUUT VOOR NATUUR- EN BOSONDERZOEK - INSTITUT PO BIORAZNOOBRAZIE I EKOSISTEMNI IZSLEDVANIYA BALGARSKA AKADEMIYA NA NAUKITE - USTAV VYZKUMU GLOBALNI ZMENY AV CR VVI - KOBENHAVNS UNIVERSITET - THE RESEARCH COMMITTEE OF THE TECHNICAL UNIVERSITY OF CRETE - BEN-GURION UNIVERSITY OF THE NEGEV - LATVIJAS UNIVERSITATE - SOVON VOGELONDERZOEK NEDERLAND - STIFTELSEN NORSK INSTITUTT FOR NATURFORSKNING NINA - EUROPEJSKIE REGIONALNE CENTRUM EKOHYDROLOGII POLSKIEJ AKADEMII NAUK - UNIVERSITATEA DIN BUCURESTI - BIOSENSE INSTITUTE - RESEARCH AND DEVELOPMENT INSTITUTE FOR INFORMATION TECHNOLOGIES IN BIOSYSTEMS - INSTITUTE OF LANDSCAPE ECOLOGY OF THE SLOVAK ACADEMY OF SCIENCES - ZNANSTVENORAZISKOVALNI CENTER SLOVENSKE AKADEMIJE ZNANOSTI IN UMETNOSTI - SVERIGES LANTBRUKSUNIVERSITET - EIDGENOESSISCHE FORSCHUNGSANSTALT WSL - - - EUR 899 820 - - - Advancing the European Long-Term Ecosystem, critical zone and socio-ecological Research Infrastructure towards ESFRI - - - EUR 899 820,01 - - - Germany - Austria - Finland - Germany - United Kingdom - France - Finland - Germany - Hungary - Italy - Portugal - Spain - Belgium - Bulgaria - Czech Republic - Denmark - Greece - Israel - Latvia - Netherlands - Norway - Poland - Romania - Serbia - Slovakia - Slovenia - Sweden - Switzerland - - - Research Organisations - Other - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - Advance_eLTER marks a crucial step in building the distributed European Research Infrastructure of Long-Term Ecosystem Research sites and socio-ecological research platforms (eLTER RI) to provide highest quality data and - services complementary to the European and global environmental RIs. The project will conduct important conceptual work and preparatory steps towards enabling European-scale investigation of the “Critical Zone”, major ecosystems and socio-ecological - systems, targeted at supporting knowledge-based decision making at various levels concerning ecosystem services and biodiversity. - - 2017-12-31, closed project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-02-2016 - Preparatory Phase and support to early phase of ESFRI projects - - - RIA - Research and Innovation action - - - Germany - - - Advance_eLTER - - - H2020-INFRADEV-2016-2 - - - 739558 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 195 454,80 - - - Single Crystalline Halide Metal Perovskites Based Optoelectronics - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The emerging methylammonium lead halide perovskites are near-ideal semiconducting materials. They can be easily formed in to thin semiconducting films, suitable for use in a wide range of optoelectronic devices including solar - cells and light emitting diodes, giving them huge potential to replace existing semiconductors in these roles. However, the films normally used in those devices are polycrystalline, containing a high density of grain boundaries and defects which - intrinsically limits the performance of these otherwise exceptional materials. The ultimate goal of this fellowship is to integrate ultrathin large scale perovskite single crystal into optoelectronic devices for the first time, leading to a step - change in device performance, comparable to that realized when single-crystal silicon was first achieved. This development will be underpinned by a detailed experimental investigation to determine the impact of single-crystal preparation on the - electronic and spectroscopic properties of perovskite film, particularly exploring charge carrier diffusion in a material with low defect density and minimal grain-boundaries. Ultimately, we will establish whether a cheap, printable material can - achieve optoelectronic devices at the thermodynamic limit – a goal of the community for the last quarter century. This project will tackle first the synthetic challenges of producing single crystalline perovskite materials with controllable - dimensions, and subsequently their integration into optoelectronic devices. This proposal takes advantage of the unique opportunity afforded by the skills of the applicant in the synthesis of controlled dimensional single crystalline perovskite - materials and the fabrication of optoelectronic devices, with the world-class materials and spectroscopic characterization expertise at the Cavendish Laboratory. The success of this proposal will place Europe at the forefront of research in the - disruptive and dynamic field of perovskite optoelectronics. - - 2019-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - PEROPTO - - - H2020-MSCA-IF-2016 - - - 750677 - - - - - THE UNIVERSITY OF WARWICK - - - EUR 195 454,80 - - - Tuning mechanical properties of elastomers with stereocontrolled π-bonds using Wittig chemistry - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Elastomer materials (or rubbers) are hugely important and widely used as a result of their ability to be deformed yet return to their original size and shape upon removal of stress. Owing to these properties and their - wide-ranging applicability, a significant body of research has been, and continues to be directed towards the discovery of new materials with specific properties for a wide array of application areas. The properties of elastomers are dependent on a - number of factors such as chain length, topology, tacticity, pendant functionality, or cross-linking density. Specifically, the mechanical characteristics of natural elastomers, e.g., those based on polyisoprene, are known to be highly dependent upon - the stereochemistry of the double bond in the isoprene unit. However, this concept is seldom exploited to modulate properties of synthetic elastomers despite the potential clear advantages to create materials in which the control over their - mechanical properties can be decoupled from their functionality. This is primarily a consequence of the inherent challenges associated with metal-catalyzed stereocontrolled polymerisations. The POLY-WITTIG project proposes to utilize the highly - practical Wittig reaction to modulate the stereochemistry of the π-bond in the elastomer backbone to inturn allow the modulation of materials properties to be controlled. Additionally, heteroatom-modified Wittig variants will be used to synthesize - and analyze mechanical properties of elastomers with heteroatom–carbon π-bonds (e.g., N=C or P=C). Thus, the versatility of Wittig chemistry will provide the unprecedented opportunity to systematically study a library of isolobally substituted - elastomers. - - 2019-06-25, ongoing project - - - 2017-06-26 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - POLY-WITTIG - - - H2020-MSCA-IF-2016 - - - 751150 - - - - - LUNDS UNIVERSITET - LUNDS UNIVERSITET - - - EUR 1 500 000 - - - Neural circuits underlying complex brain function across animals - from conserved core concepts to specializations defining a species’ identity - - - EUR 1 500 000 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The core function of all brains is to compute the current state of the world, compare it to the desired state of the world and select motor programs that drive behavior minimizing any mismatch. The circuits underlying these - functions are the key to understand brains in general, but so far they are completely unknown. Three problems have hindered progress: 1) The animal’s desired state of the world is rarely known. 2) Most studies in simple models have focused on sensory - driven, reflex-like processes, and not considered self-initiated behavior. 3) The circuits underlying complex behaviors in vertebrates are widely distributed, containing millions of neurons. With this proposal I aim at overcoming these problems using - insects, whose tiny brains solve the same basic problems as our brains but with 100,000 times fewer cells. Moreover, the central complex, a single conserved brain region consisting of only a few thousand neurons, is crucial for sensory integration, - motor control and state-dependent modulation, essentially being a ‘brain in the brain’. To simplify the problem further I will focus on navigation behavior. Here, the desired and actual states of the world are equal to the desired and current - headings of the animal, with mismatches resulting in compensatory steering. I have previously shown how the central complex encodes the animal’s current heading. Now I will use behavioral training to generate animals with highly defined desired - headings, and correlate neural activity with the animal’s ‘intentions’ and actions - at the level of identified neurons. To establish the involved conserved core circuitry valid across insects I will compare species with distinct lifestyles. - Secondly, I will reveal how these circuits have evolved to account for each species’ unique ecology. The proposed work will provide a coherent framework to study key concepts of fundamental brain functions in unprecedented detail - using a single, - conserved, but flexible neural circuit. - - 2021-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Sweden - - - BrainInBrain - - - ERC-2016-STG - - - 714599 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 171 460,80 - - - Unravelling neuronal heterogeneity in energy homeostasis regulation - - - EUR 171 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - This MSCA Reintegration proposal is aimed to study the heterogeneity of neuronal populations implicated in the maintenance of energy balance. Because of their location, neurons in the arcuate nucleus of the hypothalamus (ARC) - integrate nutrient and hormonal signals carried in the blood. Then, they regulate downstream neuron’s activity in order to adapt food intake and energy expenditure. Deregulation of energy homeostasis can lead to obesity and diabetes, two of the major - chronic diseases in the EU. AgRP neurons, an ARC population, have a prominent role in the regulation of food intake and systemic insulin sensitivity. They establish axonal projections with several brain areas and recent evidences show that each - sub-circuit can have a specific function in the regulation of food intake and/or glucose homeostasis. For this fellowship I propose to use an innovative experimental approach to investigate a specific novel AgRP neuronal subpopulation, characterized - by the expression of the UDP-receptor, P2Y6, as a first step to unravel the heterogeneity of the total population. Although P2Y6 activation increases short-term food intake, its effects on glucose homeostasis are still unknown. I plan to combine new - recombinase technologies with state of the art techniques to genetically identify the AgRP, P2Y6 subpopulation and then: 1) characterize their in vivo dynamic response to physiological activators; 2) map specific AgRP+, P2Y6+ sub-circuits and dissect - their role in each facet of energy homeostasis; and 3) investigate new molecular markers, as possible drugable targets. Results from this project will unveil new aspects of neuronal heterogeneity that participate in the regulation of energy - homeostasis and will contribute to design new strategies to curb the actual obesity trends. The completion of this MSCA fellowship represents an exceptional opportunity to reinforce my professional maturity and to develop my independent research - line. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Germany - - - ARC-NeuroHet - - - H2020-MSCA-IF-2016 - - - 752319 - - - - - LUNDS UNIVERSITET - LUNDS UNIVERSITET - - - EUR 1 499 905 - - - High Resolution Mapping of Fetal and Adult B Cell Fates During Ontogeny - - - EUR 1 499 905 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - FateMapB aims to understand how the unique differentiation potential of fetal hematopoietic stem and progenitor cells (HSPCs) contribute to functionally distinct cell types of the adult immune system. While most immune cells - are replenished by HSPCs through life, others emerge during a limited window in fetal life and sustain through self-renewal in situ. The lineage identity of fetal HSPCs, and the extent of their contribution to the adult immune repertoire remain - surprisingly unclear. I previously identified the fetal specific RNA binding protein Lin28b as a post-transcriptional molecular switch capable of inducing fetal-like hematopoiesis in adult bone marrow HSPCs (Yuan et al. Science, 2012). This discovery - has afforded me with unique perspectives on the formation of the mammalian immune system. The concept that the mature immune system is a mosaic of fetal and adult derived cell types is addressed herein with an emphasis on the B cell lineage. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Sweden - - - FatemapB - - - ERC-2016-STG - - - 715313 - - - - - KAROLINSKA INSTITUTET - - - EUR 185 857,20 - - - Pericyte-derived tumor stroma – a target for cancer therapy - - - EUR 185 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - Cancer is a devastating diagnosis since treatments to prevent a lethal outcome are limited. Tumor constitutes a complex tissue consisting of malignant cells and stromal cells. Emerging studies have shown the importance of - stroma in tumor growth, invasion, and metastasis highlighting its potential as an attractive target for cancer therapy. However, the source of tumor stroma generating cells remains elusive. Generation of connective tissue is a general feature of - scarring and fibrosis. While scarring is part of the wound healing response, fibrosis represents a failure to terminate tissue repair. In this context, tumors can be considered as “wounds that do not heal”. While studying spinal cord injury-induced - scarring, a subpopulation of perivascular cells, type A pericytes, has been shown to be a major source of the stromal scar. Type A pericytes are embedded in the vascular wall but proliferate and leave blood vessels upon injury, differentiating into - fibroblast-like cells that deposit extracellular matrix and form the stromal scar. Here, I propose to determine whether type A pericytes are a source of tumor stroma and whether blocking type A pericyte-derived stroma formation can impede cancer - progression. Single cell studies to determine pericyte heterogeneity within malignant and non-malignant tissue will be performed. This characterization of heterogeneity is important to distinguish stroma-forming pericytes from the non-forming ones - and from tumor cell-derived pericytes as described in Glioblastoma multiforme (GBM). Furthermore, by using combinations of pericyte reporter mice with genetic tools to manipulate pathways regulating cell proliferation and recruitment within specific - pericyte subpopulations, I aim to investigate underlying mechanisms mediating pericyte-derived stroma generation. Studying stroma formation using the GBM mouse model, the proposed research intends to uncover common mechanisms of tumor stroma - formation and identify new targets for therapy. - - 2018-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - PERICYTEStroma - - - H2020-MSCA-IF-2015 - - - 707449 - - - - - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - JRC -JOINT RESEARCH CENTRE- EUROPEAN COMMISSION - EUROPEAN RESEARCH SERVICES GMBH - LEIDOS BIOMEDICAL RESEARCH INC - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - STIFTELSEN SINTEF - THE UNIVERSITY OF LIVERPOOL - EIDGENOSSISCHE MATERIALPRUFUNGS- UND FORSCHUNGSANSTALT - GESELLSCHAFT FUR BIOANALYTIK MUNSTER EV - - - EUR 4 995 181 - - - European Nanomedicine Characterization Laboratory - - - EUR 5 627 303,50 - - - France - Belgium - Germany - United States - Ireland - Norway - United Kingdom - Switzerland - Germany - - - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - In order to accelerate the development of the nanomedicine business in Europe, EU-NCL interconnects 8 European and 1 American key reference facilities with a proven expertise in physical, chemical, in vitro and in vivo - biological characterisation of nanoparticles for medical applications. The objective is to reach a level of international excellence in nanomedicine characterization for all medical indication, and make it accessible to all organisations developing - candidate nanomedicines prior to their submission to the regulatory agencies in order to get the approval for clinical trials and later the marketing authorization. EU-NCL is partnered with the sole international reference facility namely the - Nanotechnology Characterisation Lab of the USA to get a faster international harmonization of analytical protocols. EU-NCL is closely connected to national medicine agencies and to the European Medicine Agency in order to permanently adapt its - analytical services to the need and requests of the regulators. EU-NCL is designed, organized and operated according to the highest EU regulatory and quality standards in order to provide a full analytical cascade of 42 assays. Within EU-NCL, 6 - analytical facilities will offer a Trans National Access to their existing analytical services but they will also develop new or improved analytical assays under the Joint Research Activities in order to keep EU-NCL at the cutting edge of the - nanomedicine characterisation. A complementary set of networking activities will make EU-NCL able to deliver to the European academic or industrial scientists the best analytical services they dramatically require for accelerating the industrial - development of their candidate nanomedicines. An exploitation and business plan will be proposed at the end of the project in order to submit a sustainable development plan beyond the initial period of 4 years. - - 2019-04-30, ongoing project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.2."> - - - INFRAIA-1-2014-2015 - Integrating and opening existing national and regional research infrastructures of European interest - - - RIA - Research and Innovation action - - - France - - - EUNCL - - - H2020-INFRAIA-2014-2015 - - - 654190 - - - - - KOBENHAVNS UNIVERSITET - - - EUR 212 194,80 - - - Island Diversity from an Eco-evolutionary Approach - - - EUR 212 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - The science of island biogeography is currently undergoing a huge resurgence of interest, due mainly to the advent of novel sources of data, most notably on geological dynamics, climate-driven sea-level changes, remotely - sensed climate, vegetation structure and topography, and, centrally, the phylogenetic relationships among species. This has paved the way for an understanding of how island geographical dynamics shape dynamics of species diversity and the evolution - of clades, but has also opened up a whole range of unanswered questions: How has the emergence of islands affected evolution in clades? How does vegetation structure and topographic complexity shape patterns of diversity? What are the roles of - cross-taxon interactions in governing these processes? And how do these patterns scale from the island to the community level? - - 2018-03-14, ongoing project - - - 2016-03-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - IDEA - - - H2020-MSCA-IF-2015 - - - 707968 - - - - - LUNDS UNIVERSITET - LUNDS UNIVERSITET - - - EUR 1 498 732 - - - Optimal diversity in immunity – to overcome pathogens and maximize fitness; moving from correlative associations to a more mechanistic understanding using wild songbirds. - - - EUR 1 498 732 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The Major Histocompatibility Complex (MHC) genes are intensively studied genes in association with disease resistance. MHC proteins are essential for initiating every adaptive immune response and MHC is probably the most - extreme example of how selection from a wide range of pathogens maintains high diversity in host immunity genes. However, the functions of the MHC proteins are only known in humans and model organisms, species that cannot be studied under natural - conditions. There is therefore a need to study function of MHC proteins in species that can be thoroughly monitored in their natural habitat under varying pathogen regimes and over several generations. These parameters can be assessed in wild - songbirds making them excellent study systems. Songbirds have large numbers of MHC gene copies, although little is known about how these affect their immune responses. Does high MHC copy number indicate that songbirds can recognize and combat more - pathogens than other animals? They do fight infections satisfactory at their breeding, stopover and overwintering sites. - - - 2021-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Sweden - - - Optimal-Immunity - - - ERC-2015-STG - - - 679799 - - - - - LUNDS UNIVERSITET - LUNDS UNIVERSITET - - - EUR 1 496 625 - - - Integrative omics of heart failure to inform discovery of novel drug targets and clinical biomarkers - - - EUR 1 496 625 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Heart failure is a leading cause of morbidity and mortality in the aging European populations. It is the end-stage of myocardial and valvular disease, arising from loss of viable or functional muscle cells in the heart. - Therapy is complicated by the multitude of causes and comorbidities of heart failure. New therapeutic targets and clinical biomarkers to individually tailor therapy (‘precision medicine’) are greatly needed. This research program aims to realize the - promise of precision medicine by applying an integrated proteomic, genomic and epidemiological approach to the underlying causes, mechanisms and consequences for heart failure. The program builds on unique Swedish nation-wide disease registers and - large biobanks, the translational research profile of the investigator and experience in genomics, epidemiology and proteomics. The program includes five work packages: (1) comprehensive plasma protein profiling through a discovery pipeline including - novel microarray-based methods and mass spectrometry in a population-based cohort of 6000 subjects and clinical cases to identify subjects at risk for heart disease; (2) assessment of heritable components to outcomes in heart disease using - nation-wide Swedish registers; (3) genome-wide discovery of variants associated with risk of and outcomes in heart disease as well as endophenotypes for cardiac structure and function, using resequencing and DNA microarrays in large population-based - cohorts including >70,000 subjects from three generations; (4) expression profiling in human heart samples and a novel human cardiomyocyte strain assay to translate genomic and proteomic findings to understanding of pathophysiological mechanisms; - (5) evaluate the clinical importance of plasma proteins and genetic variants in >3000 clinical cases. This research program is anticipated to result in new insights into the pathophysiology of heart failure and discovery of drug targets and - clinical biomarkers. - - 2021-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Sweden - - - inHForm - - - ERC-2015-STG - - - 679242 - - - - - LUNDS UNIVERSITET - LUNDS UNIVERSITET - - - EUR 2 000 000 - - - Linking Cardiometabolic Disease and Cancer in the Level of Genetics, Circulating Biomarkers, Microbiota and Environmental Risk Factors - - - EUR 2 000 000 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Cardiovascular disease (CVD), type 2 diabetes (T2D) and obesity, collectively referred to as cardiometabolic disease, together with cancer are the major morbidities and causes of death. With few exceptions, research on - cardiometabolic disease and cancer is funded, studied and clinically applied separately without fully taking advantage of knowledge on common pathways and treatment targets through interdisciplinary synergies. The purpose of this proposal is to - reveal causal factors connecting and disconnecting cardiometabolic diseases and cancer, and to understand interactions between gut microbiota, host diet and genetic susceptibility in a comprehensive prospective cohort study design to subsequently - allow design of intervention strategies to guide more personalized disease prevention. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Sweden - - - BIOMENDELIAN - - - ERC-2014-CoG - - - 649021 - - - - - LUNDS UNIVERSITET - LUNDS UNIVERSITET - - - EUR 1 268 076 - - - Discovery strategies for Dark Matter and new phenomena in hadronic signatures with the ATLAS detector at the Large Hadron Collider - - - EUR 1 268 076 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The Standard Model of Particle Physics describes the fundamental components of ordinary matter and their interactions. Despite its success in predicting many experimental results, the Standard Model fails to account for a - number of interesting phenomena. One phenomenon of particular interest is the large excess of unobservable (Dark) matter in the Universe. This excess cannot be explained by Standard Model particles. A compelling hypothesis is that Dark Matter is - comprised of particles that can be produced in the proton-proton collisions from the Large Hadron Collider (LHC) at CERN. - - - 2021-01-31, ongoing project - - - 2016-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Sweden - - - DARKJETS - - - ERC-2015-STG - - - 679305 - - - - - LUNDS UNIVERSITET - LUNDS UNIVERSITET - - - EUR 1 500 000 - - - Detailed Characterization of Spray Systems using Novel Laser Imaging Techniques - - - EUR 1 500 000 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The multiple scattering of light is a complex phenomenon, commonly encountered but rarely desired. In imaging it induces strong blurring on the recorded photographs, limiting the range of applicability and accuracy of modern - optical instruments. A typical example concerns the laser diagnostics of spray systems. The PI has revealed in 2008 a technique based on structured illumination with the important capability to remove the contributions from multiple light scattering, - allowing the unique possibility of visualising through dense sprays. Based on this acquired knowledge, the aim of this proposal is to develop and apply three novel imaging techniques for the complete characterizations of spray systems: - - 2020-02-29, ongoing project - - - 2015-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Sweden - - - Spray-Imaging - - - ERC-2014-STG - - - 638546 - - - - - LUNDS UNIVERSITET - LUNDS UNIVERSITET - - - EUR 1 492 011 - - - Sex-limited experimental evolution of natural and novel sex chromosomes: the role of sex in shaping complex traits - - - EUR 1 492 011 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The origin and evolution of sexual reproduction and sex differences represents one of the major unsolved problems in evolutionary biology, and although much progress had been made both via theory and empirical research, recent - data suggest that sex chromosome evolution may be more complex than previously thought. The concept of sexual antagonism (when there is a positive intersexual genetic correlation in trait expression but opposite fitness effects of the trait(s) in - males and females) has become essential to our understanding of sex chromosome evolution. The goal of this proposal is to understand how the interacting effects of sexual antagonism, sex-linked genetic variation, and sex-specific selection shape the - genetic architecture of complex traits. I will test the hypotheses that: 1) individual sexually antagonistic loci are common in the genome, both in separate-sexed species and in hermaphrodites, and drive patterns of sexual antagonism often seen on - the trait level. 2) That the response to sex-specific selection in sex-linked loci is usually due to standing sexually antagonistic genetic variation. 3) That sexually antagonistic variation is primarily non-additive in nature. To accomplish this, I - will use a combination of approaches, including sex-limited experimental evolution of the X chromosome and reciprocal sex chromosome introgression among distantly related populations of Drosophila, quantitative genetic analysis and experimental - evolution mimicking the creation of a novel sex chromosome in the hermaphroditic flatworm Macrostomum, and analytical and simulation modeling. This project will serve to confirm or refute the assumption that trait-level sexual antagonism reflects the - contributions of many individual sexually antagonistic loci, increase our understanding of the contribution of coevolution of the sex chromosomes to population divergence, and help provide us with a better general understanding of how genotype maps - to phenotype. - - 2021-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Sweden - - - ComplexSex - - - ERC-2015-STG - - - 678148 - - - - - HUMANITAS UNIVERSITY - - - EUR 168 277,20 - - - Transcriptional regulation by TBX18 in vascular development and disease - - - EUR 168 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - Mural cells (pericytes and vascular smooth muscle) enclose blood vessels and are critical for vascular homeostasis. Absence or malfunction of pericytes or vascular smooth muscle results in aneurysm formation in small or large - blood vessels, respectively. Our previous work showed Tbx18 is selectively expressed in mural cells of multiple adult organs. - - 2020-01-01, ongoing project - - - 2018-01-02 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Italy - - - TBX18 - - - H2020-MSCA-IF-2016 - - - 748035 - - - - - CHERRY BIOTECH - - - EUR 185 076 - - - Standard Collagenous ORgans-on-chip ENvisaging Advanced Biological Researches - - - EUR 185 076 - - - France - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - SeCtOR ENABleRs aims to develop a convenient kit for the production of partially customizable organs-on-chip. The main motivations that lead us to get involved in this effort are to provide the scientific community of an - easy-to-use, economically convenient and standardized microfluidic platform. This is expected to facilitate and promote the diffusion of advanced 3D cell culture systems in routine analyses and make results obtained from different - experiences/laboratories more comparable. In this view we envisage possible applications in the field of stem cell biology, personalized medicine, toxicology as well as advanced pre-clinical trials. The kit main components are an ad hoc designed - thermoplastic chip and a set of collagenous formulations. The chip design will allow the integration of a thermo-controller device compatible with live cell imaging techniques. A biomimetic approach and a cell-friendly crosslinking strategy will - allow to control the composition and the mechanical properties of the collagenous formulations, thus approaching the complexity of natural cell environment. The flexibility of the kit will be demonstrated by obtaining vascularized neuronal and bone - models using commercially available cells. Although some risky steps areforeseeable, the innovation in this project is more represented by the concept of organs on chip platform standardization than in significant disruptive breakthroughs. We are - convinced that the accessibility to a convenient, standardized and flexible platform is the key to exploit the huge potentialities demonstrated by microfluidics organs on chip. The implementation of the proposed multidisciplinary work plan in an - industrial environment will contribute to obtain unconventional complementary skills; understanding of the industrial perspective and needs and will finally guarantee the full exploitation of the project outcomes by establishing future SME/academics - collaboration projects. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-SE - Society and Enterprise panel - - - France - - - SeCtOR ENABleRs - - - H2020-MSCA-IF-2016 - - - 752277 - - - - - DANMARKS TEKNISKE UNIVERSITET - TECHNISCHE UNIVERSITAET MUENCHEN - TECHNISCHE UNIVERSITEIT EINDHOVEN - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - MEDIZINISCHE UNIVERSITAET WIEN - NKT PHOTONICS A/S - PHILIPS ELECTRONICS NEDERLAND B.V. - FEMTOLASERS PRODUKTIONS GMBH - ITHERA MEDICAL GMBH - EKSPLA UAB - - - EUR 3 902 716,44 - - - Multimodal, Functional Bio-Photonic Imaging - - - EUR 3 902 716,44 - - - Denmark - Germany - Netherlands - Switzerland - Austria - Denmark - Netherlands - Austria - Germany - Lithuania - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - FBI fosters education of ESRs on an emerging, multimodal imaging platform and its translation into clinical and biological applications. In FBI, 15 ESRs are trained at world-leading European academic institutions and - companies, thus forming strong interdisciplinary relations between industry, technical sciences and clinical end-users. - - 2020-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Denmark - - - FBI - - - H2020-MSCA-ITN-2016 - - - 721766 - - - - - THE FRANCIS CRICK INSTITUTE LIMITED - THE FRANCIS CRICK INSTITUTE LIMITED - - - EUR 2 118 431 - - - Telomere metabolism in Genome Stability and Disease - - - EUR 2 118 431 - - - United Kingdom - United Kingdom - - - Research Organisations - Research Organisations - - Telomeres are specialised nucleoprotein structures that protect chromosome ends from degradation and promiscuous DNA repair activities. Critically short telomeres give rise to Dyskeratosis Congenita and Hoyeraal-Hreidarrson - Syndrome (HHS), highlighting the clinical importance of maintaining telomeres. Telomeres also progressively shorten with each cell division, eventually triggering cellular senescence. Although telomerase is able to extend telomeres to solve the “end - replication problem”, its re-expression is a major route to cancer cell immortalization. Hence, telomeres and telomerase must be subject to exquisite regulation to maintain telomere homeostasis and organismal function. We have previously implicated - the Fe-S helicase RTEL1 in maintaining vertebrate telomeres, which is frequently mutated in HHS. In this ERC proposal, we will employ proteomic methods, super-resolution microscopy, biochemistry and genetic approaches to: i) investigate why - telomerase is the cause of telomere dysfunction in the absence of Rtel1, ii) how RTEL1 is controlled during the cell cycle, and iii) how this process is compromised by Rtel1 mutations in HHS. By establishing quantitative PICh to interrogate telomere - composition in unprecedented detail, we have uncovered an unappreciated compensation between RTEL1 and ATRX at telomeres and also identified SLX4IP as a key regulator of telomere recombination, which we will characterize at a mechanistic level. We - will extend our expertise in quantitative PICh and genome-wide CRISPR screens to identify novel factors that respond to or are lost from telomeres as a result of: i) induction of DNA damage at telomeres, ii) inhibition of p97 segregase, and iii) the - onset of senescence. Our proposal will lead to a greater understanding of the causes/consequences of telomere dysfunction in multiple contexts, the factors that mitigate these effects to maintain telomere homeostasis and how these processes are - compromised in human diseases. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - TelMetab - - - ERC-2016-ADG - - - 742437 - - - - - HOEGSKOLAN I BORAS - THE ROYAL COLLEGE OF ART - HERIOT-WATT UNIVERSITY - VILNIAUS DAILES AKADEMIJA - UNIVERSITAT DER KUNSTE BERLIN - TECHNISCHE UNIVERSITEIT EINDHOVEN - PHILIPS ELECTRONICS NEDERLAND B.V. - AB LUDVIG SVENSSON - PHILIPS LIGHTING B.V. - - - EUR 3 856 700,88 - - - ArcInTex ETN - - - EUR 3 856 700,88 - - - Sweden - United Kingdom - United Kingdom - Lithuania - Germany - Netherlands - Netherlands - Sweden - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - A fundamental challenge in design research today is to define the design programs that suggest how we can turn our days scientific knowledge and technical development into design for new forms of living that will provide - foundations for a more sustainable way of life. Through a cross-disciplinary and cross-national network in architecture, textiles and interaction design the consortium will build and train a new research community to take on this challenge in - practice based design research from a broader perspective, in collaboration between academia and the private sector, combining areas of design where Europe by tradition have a very strong position. The proposed ArcInTex ETN aims to strengthen the - foundations of design for new forms of more sustainable ways of living by connecting architecture, textiles and interaction design in a training network for Early stage researchers. Deepening connections between textile, architectural and interaction - design will open up for new reflective foundations of the design for living in an age of technological innovations, designing for adaptive and responsive environments connecting the scales of the body, the interior and the building. By a combination - of in depth specialization, collaborative project work training and company internship, the ESRs of the network will form a highly trained avant-garde ready to take on fundamental challenges both in academia and in the private sector building their - work practice on new ideas of material thinking and design thinking with emphasis on sensitive design expressions for reflective living. By strong focus on practice based design research the ETN will contribute to further establish design research at - a level similar to that of engineering science in areas of special importance for the design of our future ways of living, which is crusial for academia and private sector collaboration in the given areas of design research. - - 2018-12-31, ongoing project | - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Sweden - - - ArcInTex ETN - - - H2020-MSCA-ITN-2014 - - - 642328 - - - - - INSTYTUT LACZNOSCI PANSTWOWY INSTYTUT BADAWCZY - - - EUR 134 462,40 - - - Open-source freeware for fiber optic communication and sensing simulations - - - EUR 134 462,40 - - - Poland - - - Research Organisations - - To meet the constantly increasing traffic in optical networks due to ever growing requirements of society spectral efficiency should be increased by using, an advanced modulation formats and reduced channel spacing. This - results in increased spectral power density and interferences with an adjacent channels. Furthermore, dynamic links switching in the network is foreseen. All this makes the physical layer simulations an important task in network modeling, helping to - optimise the transmission range of individual optical paths. The commercial tools designed to simulate fiber optic systems, are rather expensive and there is no simpler alternative software of this type. - - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Poland - - - SIMFREE - - - H2020-MSCA-IF-2016 - - - 748767 - - - - - AARHUS UNIVERSITET - - - EUR 200 194,80 - - - Gregory Nazianzen's methodeology of the theological arguing - - - EUR 200 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - The objectives of the research project are to show how a strong focus on an early Christian author’s use of classical rhetoric and philosophy (fx. Plato and Aristotle) can deepen our understanding of style and content of - ancient Christian texts. This will be exemplified by detailed rhetorical and philological analyses of Gregory Naziansen’s five theological orations. Modern literary theories of reception will be employed to illuminate how Gregory used classical - rhetoric and philosophy. The research project will thus revitalize traditional methods of classical philology and combine them with modern literary theories. Further I will study the composition of the cycle of the five theological orations arguing - that they are written as a coherent whole. Each oration will also be studied separately clarifying which rhetorical and philosophical methods and techniques the author has used, which connections with classical pagan and early Christian (Alexandrian - school) traditions they show, and which kind of theological arguing (positive and negative theology) they are characterized by. The proposed research will at the same time serve as a model for how philological and rhetorical analyses and theories of - reception can be used as a tool for analyzing other ancient Christian texts. - - 2017-07-29, closed project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - Gregory - - - H2020-MSCA-IF-2014 - - - 660894 - - - - - GOETEBORGS UNIVERSITET - - - EUR 185 857,20 - - - Permafrost thaw – decadal responses to climate change - - - EUR 185 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - Permafrost soils contain approximately 1672 Petagram carbon (C), twice the amount of the current atmosphere, and constitute 50% of the world’s belowground C pool. Along with the current change in climate these high latitudinal - soils experience increased temperatures, more than any other region, with permafrost degradation as a result. Such thaw of permafrost releases ancient organic matter that has been stored in the frozen soils for centuries. Following microbial - degradation, this organic matter can be released to the atmosphere as carbon dioxide (CO2), methane (CH4) and nitrous oxide (N2O), further influencing the climate systems. Thus, a changed climate leads to server alterations of the carbon (C) and - nitrogen (N) balance in Arctic and high altitude ecosystems. However, research up to today has mostly focused on the impact of permafrost thaw and the time horizon immediately following this degradation. - - - 2018-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - PERMTHAW - - - H2020-MSCA-IF-2014 - - - 657627 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 2 348 483 - - - Specialized Ribosomes for Neuronal Protein Synthesis - - - EUR 2 348 483 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - The ability of the nervous system to respond adaptively relies on modifications to existing proteins as well as changes in gene transcription and mRNA translation. It is now clear that synapses possess the capacity for local - protein synthesis, owing to the localization of ribosomes and mRNAs within dendrites. There is emerging interest in the possibility that ribosomes, as cellular machines, are not as static as typically assumed- and may be heterogeneous in composition - and specialized for particular functions and cellular compartments. Intriguingly, several studies have noted the presence of ribosomal protein mRNAs in the dendrites and axons, raising the possibility that locally synthesized ribosomal proteins might - serve to modify the local ribosome population. Amongst the players in protein synthesis, many signaling proteins, RNA-binding proteins, and most translation factors have been considered as potential regulatory hubs. The ribosomes, thus far, have not - been considered. Here we propose to discover the nature and diversity of ribosomes present in neurons, their dendrites and their synapses in the rodent brain. Using a combination of RNA-sequencing, Mass Spectrometry, Fluorescence In situ - Hybridization, and new labelling approaches to visualize nascent proteins, we will determine whether neuronal ribosomes are heterogeneous and specialized in different subcellular compartments. The proposed experiments will determine the relationship - between the ribosome composition and the neuronal mRNAs that undergo translation. We will also examine how plasticity sculpts the ribosome population to regulate the changes in the proteome that are dynamically regulated by ongoing synaptic events - and plasticity. - - 2022-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - NeuroRibo - - - ERC-2016-ADG - - - 743216 - - - - - TECHNISCHE UNIVERSITEIT EINDHOVEN - UNIVERSITEIT UTRECHT - UNIVERSITEIT GENT - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - HELSINGIN YLIOPISTO - UNIVERSITE DE BORDEAUX - CHEMCONNECTION BV - STICHTING KATHOLIEKE UNIVERSITEIT - - - EUR 3 894 543,36 - - - Nanomedicine: an integrative approach - - - EUR 3 894 543,36 - - - Netherlands - Netherlands - Belgium - United Kingdom - Finland - France - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - Nanomedicine (NM) is regarded as one of the most promising applications of nanotechnology, as it would allow the development of tailored therapies, with a high level of selectivity and efficacy. Although much research has been - performed over the past decades, translation from academia to commercial application remains disappointingly low. Reasons that explain the current moderate success of NM are: (1) promising preclinical results are often poorly predictive for clinical - safety and effectiveness, (2) the efficient, scalable and reproducible GMP production of nanocarriers has proven to be challenging and (3) regulatory frameworks are not yet fully equipped to efficiently facilitate the introduction of novel - nanomedicines. These obstacles are often encountered since the developmental process from carrier design to clinical assessment is performed by a range of scientists from different backgrounds who have difficulty interacting and communicating with - each other to clearly understand the necessary design criteria and the scope and limitations of NM. - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Netherlands - - - NANOMED - - - H2020-MSCA-ITN-2015 - - - 676137 - - - - - UNIVERSITAET LEIPZIG - - - EUR 159 460,80 - - - Marine Stratocumulus Cloud Cover and Climate - - - EUR 159 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - Global climate change is forced by the balance of the warming due to anthropogenic greenhouse gases and the cooling due to anthropogenic aerosol pollution particles. Among these, the cloud-mediated aerosol radiative forcing is - by far the main component of the uncertainty. Marine stratocumulus clouds in particular play a decisive role due to their very large net effect on the Earth's radiative energy budget. Stratocumulus clouds occur in the two main regimes of open and - closed cells that differ significantly by their cloud cover, and thus by their radiative effect. The main hypothesis of this proposal is that anthropogenic aerosols exert a substantial radiative forcing via their potential to impede or delay the - transition from closed to open cells marine stratocumulus, and that this presumably un-buffered effect is not accounted for in forcing estimates by current climate models. - - 2018-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - MSCCC - - - H2020-MSCA-IF-2015 - - - 703880 - - - - - ITA-SUOMEN YLIOPISTO - - - EUR 267 793,20 - - - An interdisciplinary approach to uncover the mechanisms of progression of cartilage damage at the cellular and tissue levels - - - EUR 267 793,20 - - - Finland - - - Higher or Secondary Education Establishments - - Joint injuries are very frequent, especially among young people. Such injuries seldom heal and over time can lead to cartilage degeneration and ultimately osteoarthritis. Although, it is generally assumed that excessive - mechanical loading post-injury can cause or accelerate the progression of cartilage degeneration, the precise mechanisms involved in the pathological processes at different structural length scales are still not fully understood. Thus, novel - approaches for understanding structure-function relationships from the cell to tissue level in both health and disease are necessary. The overall aim of this research is to investigate the mechanisms of cartilage damage progression at different - levels of tissue organization. The novelty of this research lies in the highly interdisciplinary approach of combining an in vitro model of OA progression with the state-of-the-art materials testing devices, computational modeling and sophisticated - microscopic, spectroscopic and molecular biology techniques to carefully assess the mechanics, structure, composition and gene expression on cell and tissue levels. The novel data obtained from this research will shed light on the key - mechanobiological pathways by which cartilage cells maintain healthy tissue or mount a healing response following tissue injury and excessive loading. This project is conducted as an international collaboration between University of Eastern Finland, - Kuopio, Finland and Massachusetts Institute of Technology, Cambridge, USA. This represents a unique opportunity to bring together the complementary skill sets of Dr. Florea, Dr. Korhonen’s group and Prof. Grodzinsky’s group, with their expertise in - biomechanics, computational modeling, biochemistry and cartilage biology. The mutually beneficial collaboration between Europe and USA can advance the field of cartilage research with significant potential to provide novel strategies to - reduce/prevent cartilage degeneration for patients in Europe and beyond. - - 2019-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Finland - - - INpaCT - - - H2020-MSCA-IF-2015 - - - 702586 - - - - - UNIVERSITA CA' FOSCARI VENEZIA - - - EUR 180 277,20 - - - Visualising Engineered Landscapes: an archaeological approach to unlock environmental resilience and sustainability in antiquity - - - EUR 180 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - Contemporary anthropogenic landscapes were shaped by centuries of human action. Land surveying and division were the first forms of widespread landscape engineering performed by pre-industrial societies. Among those, the most - complex was unquestionably the Roman Centuriation, which still characterise the rural landscapes of many European countries. Notwithstanding its impact on modern European land organisation, the principles underlying the design approach used by Roman - land commissioners are still largely ambiguous. The proposed project thus aims to illuminate the process of landscape engineering undertaken in antiquity by the Roman surveyors and contribute to the discipline of landscape engineering by injecting a - new body of evidence into the debate about past land division and design in order to inform models of sustainable practice for contemporary landscape management. - - 2017-07-19, closed project - - - 2015-07-20 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Italy - - - VEiL - - - H2020-MSCA-IF-2014 - - - 656337 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 246 668,40 - - - Evolution of the social brain: How social complexity affects individual cognition in ants - - - EUR 246 668,40 - - - France - - - Research Organisations - - This project aims to answer a significant open question in evolutionary neurobiology: how social complexity shapes the brain structure, its associated metabolic costs, and the behavioural capability of individual members of a - society. The Social Brain Hypothesis proposes that the complexity of living in group influences encephalization in vertebrates, but this theory has not been critically tested in invertebrate species. Social insects such as ants have miniaturized - brains that nevertheless support highly coordinated collective behaviour and striking individual cognitive abilities. This collective behaviour produces an “externalized” distributed processing of information that may reduce energetic expenses in - individual brains. - - - 2018-07-31, ongoing project | - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - France - - - BrainiAnts - - - H2020-MSCA-IF-2014 - - - 660976 - - - - - STOCKHOLMS UNIVERSITET - STOCKHOLMS UNIVERSITET - - - EUR 2 492 834 - - - Earth Resilience in the Anthropocene (ERA)Integrating non-linear biophysical and social determinantsof Earth-system stability for global sustainabilitythrough a novel community modelling platform - - - EUR 2 492 834 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In 2015, the UN Sustainable Development Goals (SDGs) and the Paris Agreement on climate recognised the deteriorating resilience of the Earth system in the Anthropocene. Maintaining Earth in the interglacial state that enabled - the world’s societies to evolve over the past 12,000 years will require industrialised societies to embark on global-scale social transformations. Otherwise, there is a real risk of crossing tipping points in the Earth system triggering abrupt and - irreversible changes. - - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Sweden - - - ERA - - - ERC-2016-ADG - - - 743080 - - - - - LATVIJAS UNIVERSITATE - - - EUR 145 904,40 - - - Multimodal Spectral Imaging for Canine Skin Erythema Estimation: from the Lab to the Clinic – DogSPEC - - - EUR 145 904,40 - - - Latvia - - - Higher or Secondary Education Establishments - - In this action, we propose a novel portable and cost-effective multispectral device for smartphones that will monitor dog skin health in terms of erythema. Up to 50-% of European households own a dog, and the five of the ten - most common reasons for a veterinary visit can be reflected in erythematous skin. Currently, there are no methods for the objective estimation of the intensity of erythema. In this action, we will first develop multispectral near-infrared device for - the detection of extra absorption peaks of hemoglobin. In order to learn about hemodynamics, we will continue with objective measurements of capillary refill time. Then, we will develop a device for the multimodal acquisition of visible multispectral - and fluorescence images and near-infrared multispectral data. This will serve for an estimation of erythema intensity by calculating an erythema index. The latter will be validated using existing dermatological tests (e.g. CADESI) in order to study - whether erythema index can replace erythema visual assessment. Finally, we will investigate if there is any correlation between erythema and underlying causes (tumors). The proposed methods can simplify and improve current diagnostic procedures in - veterinary dermatology. - - 2019-08-21, ongoing project - - - 2017-08-22 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Latvia - - - DogSPEC - - - H2020-MSCA-IF-2016 - - - 745396 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 158 121,60 - - - Impact of Intrapartum Antimicrobial Prophylaxis as an early determinant in Microbiome Development - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - During the last decades, changes in diet and lifestyle have increased the risk of non-communicable diseases in the western countries. It is known that once they are established in the childhood, they continue into adult life - with the associated negative impact on health, quality of life and health care costs. The correct establishment of the intestinal microbiota (IM) at the beginning of life plays a key role in health, reducing risk of chronic disease. Some factors - affecting this process have been studied; however, other like the intrapartum antimicrobial prophylaxis (IAP), in spite of been present on over 30% of total deliveries, have been much less studied. It is already known that at least 11 types of - broad-spectrum antibiotics cross the placenta and reach the foetus. Given the increasingly evident relationship between early microbiota, later disease risk and the rising worries regarding antimicrobial resistances, there is an urgent need to assess - the potential adverse consequences of IAP in the establishment of the IM and resistome. This project will be the first to study mechanisms orchestrating the impact of IAP on the neonatal IM establishment. The objectives are: identify the alterations - induced by IAP in the neonatal IM development; identify the antibiotic resistance genes that the IM carried as consequence of IAP; study the potential role of infant feeding in the modulation of the microbiota after IAP administration and design of - specific dietary strategies for minimising the impact of IAP on the IM establishment. Moreover, if the breast-milk exerts a protective role, it would help to strengthen the maternal breast-feeding recommendations. Following this study, doctors will - be better able to address the consequences to make knowledge-based decisions about IAP treatment in those situations where it is not extremely mandatory. Besides, the present project will represent a worthy opportunity for the applicant to improve - her research competences and career. - - 2019-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - IAPEMIDE - - - H2020-MSCA-IF-2016 - - - 749255 - - - - - ROYAL COLLEGE OF SURGEONS IN IRELAND - TECHNISCHE UNIVERSITAET DRESDEN - UNIVERSITE DU LUXEMBOURG - KATHOLIEKE UNIVERSITEIT LEUVEN - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - ONCOMARK LIMITED - UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN - OPTIMATA LTD - KRAEFTENS BEKAEMPELSE - PROTATOUANS - ETAIREIA EREYNAS VIOTECHNOLOGIAS MONOPROSOPI ETAIREIA PERIORISMENIS EYTHINIS - UNIVERSITAET STUTTGART - UNIVERSITAETSKLINIKUM AACHEN - - - EUR 3 583 870,17 - - - Exploiting MELanoma disease comPLEXity to address European research training needs in translational cancer systems biology and cancer systems medicine - - - EUR 3 583 870,17 - - - Ireland - Germany - Luxembourg - Belgium - Germany - Ireland - Ireland - Israel - Denmark - Greece - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Novel treatment options and associated personalised, patient-tailored therapies need to be explored and developed for highly heterogeneous and chemotherapy resistant cancers, such as malignant melanoma. This can only be - achieved by industry-academia collaborations in newly emerging, innovative research disciplines such as translational cancer systems biology and systems medicine. These disciplines and the associated European training needs provide the foundation for - the MEL-PLEX ETN. MEL-PLEX aims to understand the network-level and multi-scale regulation of disease-relevant signalling in melanoma through a combination of quantitative biomedical and computational research approaches that go significantly beyond - the current state-of-the-art. Coordinated by the RCSI Centre for Systems Medicine, MEL-PLEX will train 15 early stage researchers through a highly interdisciplinary and intersectoral research training programme. MEL-PLEX comprises 11 beneficiaries - and 7 partner organisations from 11 countries, including European and international leaders in personalised melanoma therapy, melanoma systems biology and cancer systems medicine. MEL-PLEX aims to (i) achieve an unmatched depth of molecular and - mechanistic disease understanding, (ii) will exploit this knowledge to develop and validate predictive models for disease progression, prognosis and responsiveness to current and novel (co-)treatment options, and (iii) will provide superior and - clinically relevant tools and biomarker signatures for personalising and optimising melanoma treatment. The MEL-PLEX ETN addresses current needs in academia and the private sector for researchers that have been trained in an environment that spans - across biology, medicine and mathematics, that can navigate confidently between clinical, academic and private sector research environments, and that have developed an innovative and creative mindset to progress research findings towards - applications. - - 2018-11-30, ongoing project | - - - 2014-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Ireland - - - MEL-PLEX - - - H2020-MSCA-ITN-2014 - - - 642295 - - - - - UNIVERSITAET BERN - - - EUR 175 419,60 - - - The cryptic path of tumor-microenvironment interactions in prostate cancer - - - EUR 175 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - In the developed countries, prostate cancer is the second leading cause of cancer-associated death in men, with a predicted rate of 10.9/100.000 men in Europe in 2016. Mortality results when prostate cancer has spread to other - organs (metastasis, particularly to the bone). Prostate cancer prognosis and follow-up is mainly performed with routine blood test (prostate specific antigen levels). However, the low/high risk of metastasis for individual patients cannot always be - accurately assessed due to tumor heterogeneity and differential rate of tumor progression. Thus, a more thorough understanding of the metastatic processes is needed. - - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - STOPCa - - - H2020-MSCA-IF-2016 - - - 748836 - - - - - KAROLINSKA INSTITUTET - - - EUR 185 857,20 - - - Novel Resolvin D3: its Role and Actions in the Resolution of Aortic Valvular Inflammation and Stenosis - - - EUR 185 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - Aortic valve stenosis is a progressive inflammatory disorder with poor prognosis if left untreated. Currently the only available treatment is invasive surgical replacement of the valve, therefore new therapeutic strategies are - needed. Resolution of inflammation is an active process orchestrated by endogenous specialized proresolving lipid mediators (SPM). These include the resolvins that actively promote catabasis via their potent actions in anti-inflammation, - proresolution, tissue regeneration and pain reduction. Recently the complete stereochemistry of resolvin D3 (RvD3) was established. Given its highly potent anti-inflammatory and proresolving actions in murine models and with human cells its role and - actions in aortic stenosis (AS) remains to be uncovered. Thus, a goal of this proposal is to elucidate endogenous resolution programs in human aortic valves and define the role and action of RvD3 in AS and calcification. To address this the candidate - will employ LC-MS-MS based LM metabololipidomics combined with clinically relevant parameters as well as biochemical and cellular assessments in samples from AS patients. In addition, RvD3 will be used as treatment in a novel preclinical model of - murine AS. Implementation of the proposed project will maintain and enhance the candidate’s position at the forefront in the field of resolution biochemistry with advances into valvular pathology. Unraveling the role of RvD3 and resolution programs - in aortic inflammation and resolution may enhance current understanding of the molecular mechanism contributing to chronic cardiovascular inflammation and introduce a novel concept for the pathology AS. Furthermore, it may lead to novel therapeutic - strategies with a potential to slow or halt the hemodynamic progression of stenosis via turning on resolution programs. - - 2017-10-31, closed project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Sweden - - - RvD3-RAVIS - - - H2020-MSCA-IF-2014 - - - 656817 - - - - - UNIVERSITAET LEIPZIG - - - EUR 239 860,80 - - - Modeling Common Ground - - - EUR 239 860,80 - - - Germany - - - Higher or Secondary Education Establishments - - Language is inherently ambiguous. The meaning of words and sentences depends on the identity of the communicative partners and the nature of the context. In simple behavioral experiments children and adults can use a wide - variety of social-contextual cues (jointly known as “common ground”) to interpret ambiguous utterances. But this limited empirical evidence – especially in the developmental context – does not live up to the theoretical importance of common ground: - In theory, common ground is not only involved in online language use but it is also a necessary prerequisite to learn language in the first place. Studying the development of children’s ability to form and use common ground is therefore crucial to - understand the psychological foundation of language. It is still unknown how both adults and children integrate different social-contextual cues in complex, naturalistic interactions. Bayesian modeling provides a mathematical framework for - formalizing theoretical assumptions about this interaction and deriving quantitative predictions about new experimental situations. - - 2020-09-10, ongoing project - - - 2017-09-11 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Germany - - - ModelingCommonGround - - - H2020-MSCA-IF-2016 - - - 749229 - - - - - Eidgenössische Technische Hochschule Zürich - - - EUR 265 840,20 - - - Multi-language text summarization - - - EUR 265 840,20 - - - Switzerland - - - Higher or Secondary Education Establishments - - In our daily life, we are submerged by huge amounts of text, coming from different sources such as emails, news, reports, and so on. The availability of unprecedented volumes of data represents both a challenge and an - opportunity. On one hand, it can lead to information overload, a phenomenon that limits one’s capacity to understand an issue and act in the presence of too much information. On the other hand, the effective harnessing of this information has - undeniable economical potential. Furthermore, In the European context, special needs to be put to multilingualism to guarantee global access to high quality information. - - 2020-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Switzerland - - - ML-TEXTSUM - - - H2020-MSCA-IF-2016 - - - 748900 - - - - - SOFIISKI UNIVERSITET SVETI KLIMENT OHRIDSKI - SOFIISKI UNIVERSITET SVETI KLIMENT OHRIDSKI - - - EUR 150 000 - - - Bottom-up Energy Efficient Emulsification and Structured Materials - - - EUR 150 000 - - - Bulgaria - Bulgaria - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Bottom-up Energy-Efficient Emulsification and Structured Materials Fabrication. - - 2018-10-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Bulgaria - - - ShipShape - - - ERC-2017-PoC - - - 766656 - - - - - UNIVERSIDAD COMPLUTENSE DE MADRID - - - EUR 158 121,60 - - - The Kurds in Syria: A complex interplay between local, regional and transnational - - - EUR 158 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - While extremely graphic images from the Syrian civil war appearing at the world media, smiling young Kurdish female guerrillas at the cover of magazines such as Elle, Marie Claire presented another picture. Kurdish fighters - have become driving forces in offensives against ISIS and gained worldwide news coverage. However, the story of the Kurds in Syria is more than this. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - ROJAVA - - - H2020-MSCA-IF-2016 - - - 748155 - - - - - KAROLINSKA INSTITUTET - - - EUR 185 857,20 - - - Dissecting the human microbiota-macrophage-innate lymphoid cell crosstalk in the lung - - - EUR 185 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - It is poorly understood how macrophages interact with other cells and commensal microbes (microbiota) to achieve the balance between barrier immunity and tissue homeostasis in the lung. Novel experimental systems are required - to investigate the interaction between macrophages, innate lymphoid cells (ILC), and the microbiota since the immune system, inflammatory responses, and microbiota differ between mice and humans. However, studies in humans are limited by ethical - constraints. To overcome this limitation, I will use mice with a human immune system (humanized mice) that are colonized with a human microbiota. The supervisor Dr. Willinger has drastically improved humanized mice by providing critical human factors - through knock-in gene replacement. Using this unique tool, I will test the hypothesis that signals from the human microbiota regulate lung immune function through effects on alveolar macrophages and ILC and pursue the following objectives: (1) Define - the role of human monocytes/macrophages in the homeostasis of lung ILC; (2) Determine how the human microbiota regulates lung macrophages and ILC; (3) Dissect the role of human monocytes/macrophages in lung inflammation. To achieve these aims, I will - employ the state-of-the-art model to reconstitute the human lung immune system and microbiota in the mouse. I will deplete human alveolar macrophages and monocyte subsets to determine how these cells regulate ILC differentiation and lung - inflammation. This will be complemented by studies in germ-free humanized mice colonized with a human lung microbiota to investigate immune regulatory effects of the local microbiota. The project will generate critical new insights into the human - microbiota-macrophage-ILC crosstalk that cannot be obtained with other experimental approaches. My multidisciplinary approach involving humanized mice, immunology, and germ-free studies has the potential to discover novel approaches to treat human - lung disease. - - 2018-11-30, ongoing project | - - - 2016-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - Sweden - - - MICRO-MACRO-ILC - - - H2020-MSCA-IF-2015 - - - 701258 - - - - - INSTITUT D'ESTUDIS ESPACIALS DE CATALUNYA FUNDACION - - - EUR 158 121,60 - - - SmartClouds Orbital Dynamics and Control - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - This Action, entitled “SmartClouds Orbital Dynamics and Control” (SmartCloudsODC), will deliver radical new methodologies for orbital dynamics and control of multi-spacecraft systems to investigate new easy-accessible - space-based products and services for Europe. Thanks to the advanced in Miniaturised Electromechanical Systems technology, a new class of low-cost, low-risk space missions - based on multiple cooperative elements - is arising. Assuming smart-clouds - of vast numbers of femto-spacecraft, this Action will move from the classic - deterministic - celestial mechanics approach to a new paradigm in space mission design - based on stochastic analyses. - - 2018-08-31, Grant Agreement terminated - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - SmartCloudsODC - - - H2020-MSCA-IF-2014 - - - 655534 - - - - - UNIVERSITAT DE VALENCIA - UNIVERSITAT DE VALENCIA - - - EUR 1 827 375 - - - A Chemical Approach to Molecular Spin Qubits: Decoherence and Organisation of Rare Earth Single Ion Magnets - - - EUR 1 827 375 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - "Coordination Chemistry and Molecular Magnetism are in an ideal position for the rational design of Single-Molecule Magnets which can be used as molecular spin qubits, the irreducible components of any quantum technology. - Indeed, a major advantage of molecular spin qubits over other candidates stems from the power of Chemistry for a tailored and inexpensive synthesis of systems for their experimental study. In particular, the so-called Lanthanoid-based Single-Ion - Magnets, which are currently the hottest topic in Molecular Magnetism, have the potential to be chemically designed, tuning both their single-molecule properties and their crystalline environment. This will allow the independent study of the - different quantum processes that cause the loss of quantum information, collectively known as decoherence. The study of quantum decoherence processes in the solid state is necessary both to lay the foundations for next-generation quantum technologies - and to answer some fundamental questions. - - 2020-07-31, ongoing project - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Spain - - - DECRESIM - - - ERC-2014-CoG - - - 647301 - - - - - LUNDS UNIVERSITET - - - EUR 185 857,20 - - - The epigenetic basis of early-life effects in a wild bird exposed to urban environmental stress - - - EUR 185 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - The impact of urbanisation on wildlife is of increasing global concern. It is well known that exposure to urban environmental stressors increases oxidative stress. More recently, exposure to pollutants has been shown to - directly modify the epigenome, via DNA methylation, in humans. Oxidative stress may be a key mechanism mediating epigenetic modifications in response to pollutant exposure and thereby influencing development, disease resistance and ageing. This - multidisciplinary project outlines the first study to date of the epigenetic basis of early-life effects in a wild bird exposed to urban environmental stress. Early-life stress exposure can have profound effects on phenotypic development and - long-term fitness. Epigenetic mechanisms are influenced by environmental cues during development and therefore may mechanistically link developmental conditions with later-life performance. Using urban and rural populations of birds, we will perform - experimental studies in the field and lab to examine whether increased oxidative stress during development modifies patterns of global and gene-specific DNA methylation and thereby alters genome stability (via DNA damage and telomere attrition) and - expression of antioxidant genes. To achieve this, we propose a new framework to explain how the modification of DNA methylation and telomere length may be linked and decoupled by the direct and indirect effects of oxidative stress at different stages - during development. Pilot data support this framework. This will enable us to disentangle the mechanistic relationships between exposure to urban stressors, oxidative stress, DNA methylation and telomere dynamics during development and the - consequences for growth and survival in an altricial bird species. The project has implications for multiple EU policies and H2020 focus areas. By combining the researcher’s existing expertise with new skills and opportunities, the project will - enhance career prospects and advance the research field. - - 2017-03-31, closed project | - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - URBANEPIGENETICS - - - H2020-MSCA-IF-2014 - - - 659643 - - - - - SCIENCE BUSINESS PUBLISHING LIMITED - SCIENCE BUSINESS PUBLISHING LIMITED - EVRO-SREDOZEMSKA UNIVERZA - CIENCIA VIVA-AGENCIA NACIONAL PARA A CULTURA CIENTIFICA E TECNOLOGICA - VISION2020 NETWORK LTD - ASSOCIATION EUROPEENNE DES EXPOSITIONS SCIENTIFIQUES TECHNIQUES ET INDUSTRIELLES - UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK - EIRMA EUROPE AISBL - SVEUCILISTE U ZAGREBU MEDICINSKI FAKULTET - - - EUR 958 759 - - - ERC = ScienceSquared - - - EUR 958 759 - - - United Kingdom - United Kingdom - Slovenia - Portugal - United Kingdom - Belgium - Ireland - Belgium - Croatia - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Higher or Secondary Education Establishments - Other - Higher or Secondary Education Establishments - - The ERC is a great success scientifically, and now wants to broaden its popular and political support. But it has a problem: Most EU citizens don’t care about some Brussels agency they never heard of. The solution is in the - ERC’s mandate: frontier research. It has science – the cutting edge variety, that can capture the imagination, change the world and stimulate curiosity. We have seen the power of a fundamental science story elsewhere, and how it can focus attention - on the institution behind it: the Higgs boson and CERN. It takes high scientific achievement, great story-telling, a tight focus, creative communications and a sustained effort to build a mass following in science. We believe the ERC can achieve this - – to matter as the source of cool science, to students, investors, policy makers, researchers, and all citizens generally, in all 28 EU member-states and beyond. The ERC can invent science and mirror it back to society. In short, ERC = - ScienceSquared. - - 2019-03-31, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-SUPPORT-2014 - ERC Support for novel ways to highlight the work funded by the ERC and reach out a wider public. - - - - CSA - Coordination and support action - - - United Kingdom - - - ScienceSquared - - - ERC-2014-SUPPORT-1 - - - 672302 - - - - - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - - - EUR 150 000 - - - That Special First Time - Boosting Turnout and Satisfaction amongst First Time Voters - - - EUR 150 000 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - "FIRSTTIME is dedicated to generating new unique instruments that Election Management Bodies (EMB) worldwide can use to organise a bespoke electoral experience for first time voters and increase their satisfaction and turnout. - We will partner with EMBs to test them in real elections. - - - 2017-06-30, closed project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2015 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - FIRSTTIME - - - ERC-2015-PoC - - - 680486 - - - - - UNIVERSITAT DE VALENCIA - - - EUR 158 121,60 - - - Spintronics with Non-Conventional 2D Materials - - - EUR 158 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - Since the discovery of graphene in 2004, a member of the two-dimensional (2D) materials family, the amazing properties of these materials at the single layer level have attracted an enormous attention. Thanks to the plethora - of available compounds, an extremely wide richness of properties covering the full range of electrical and magnetic behaviors is expected. For spintronics, the combination of 2D layers in designed multilayer stacks can be envisaged as a way to obtain - highly optimized modules that, combined altogether, will allow the realization of fully 2D advanced spintronic devices (2D spinFETs, 2D spinOLEDs, 2D MTJs for 2D memories, etc..) leading towards their ultimate miniaturization and engineering. - - - 2017-05-17, closed project - - - 2015-05-18 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - SPIN2D - - - H2020-MSCA-IF-2014 - - - 659378 - - - - - UNIVERSITAT DE BARCELONA - - - EUR 170 121,60 - - - Multitarget compounds with therapeutic potential against Alzheimer disease: Design and in vitro studies - - - EUR 170 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - This fellowship will provide a prolific researcher with an internationally competitive, multi-disciplinary research training at the Chemistry/Biology interface in an EU leading Bioinorganic chemistry team, preparing her to - obtain her goal of a faculty position in the EU and her own research team in Medicinal Chemistry. - - 2018-04-22, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - CHELALZ - - - H2020-MSCA-IF-2014 - - - 656820 - - - - - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - - - EUR 183 454,80 - - - Scientific Models, Fiction and Imagination - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The project aims to systematically explore a novel approach to model-based reasoning drawing on the relationship between the debate on the nature of scientific models from philosophy of science and the debate on the nature of - fiction from aesthetics. Many contemporary philosophers of science argue that learning with models involves a special cognitive function that they call “surrogative reasoning” or “model-based reasoning”. Understanding model-based reasoning can be - divided into two subprojects: what model-systems are (SP1) and how knowledge about the model is converted/interpreted into knowledge about the target (SP2). Work within (SP1) will be driven by the hypothesis that scientific models are akin to the - fictions of literature and the arts. Work within (SP2) will be driven by the hypothesis that interpretation is mediated by a representational relation converting a fact about the model system into a claim about the target system. The project relies - on the normative and descriptive methodology of analytical naturalised philosophy of science, which focuses on examples and case studies. The project will benefit from the combination of Frigg’s expertise in philosophy of science and modelling and of - Salis’ original specialization in the areas of aesthetics and the philosophy of fiction. Furthermore, we will collaborate with the experts from the CPNSS Philosophy of Physics project at LSE, with the decision theorists and social choice experts in - the LSE’s Choice Group and with the CATS (Centre for the Analysis of Time Series) group on climate models based at LSE. This study will lead to new insights into the nature of scientific modelling and model-based reasoning and it will open new lines - of research by injecting a new and fresh perspective from aesthetics into philosophy of science. - - 2017-09-30, closed project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SCIMOD - - - H2020-MSCA-IF-2014 - - - 654034 - - - - - LINKOPINGS UNIVERSITET - POLITECNICO DI MILANO - ALCATEL-LUCENT DEUTSCHLAND AG - - - EUR 1 043 441,28 - - - Anticipatory Networking Techniques in 5G and Beyond - - - EUR 1 043 441,28 - - - Sweden - Italy - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The rapid growth in mobile network data traffic contributed to the unprecedented speed of 4G LTE adoption, creating the need of sustainable capacity growth in next generation of wireless systems, namely 5G. A key success - factor of 5G is network and management system design for flexibility by prediction and adaptation. To this end, anticipation is a promising new approach. By predicting and adapting to upcoming events at various time scales, an anticipatory network - improving the operation quality and efficiency. First, network resources ranging from spectrum and buffers can be managed optimally to meet users’ requirements. Second, network operators can jointly plan how to share infrastructures and resources to - meet their demands at lower costs and better energy efficiency. - - - 2019-04-30, ongoing project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-EID - Marie Skłodowska-Curie Innovative Training Networks (ITN-EID) - - - MSCA-ITN-EID - European Industrial Doctorates - - - Sweden - - - ACT5G - - - H2020-MSCA-ITN-2014 - - - 643002 - - - - - VIB - - - EUR 160 800 - - - Nanobody-enabled Structural Investigation of a G Protein-Coupled Receptor-Arrestin Complex - - - EUR 160 800 - - - Belgium - - - Research Organisations - - Although many thousands of transient protein-protein interactions (PPIs) are known, there is a disturbing paucity of high-resolution structures of the resulting complexes and the difficulties involved in experimentally - determining these atomic structures remain essentially unaddressed. - - 2017-06-30, Grant Agreement terminated - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Belgium - - - NESIAC - - - H2020-MSCA-IF-2014 - - - 660753 - - - - - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - - - EUR 183 454,80 - - - Adolescents, Parents and Digital Media: Looking for the pattern that dis/connects - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - This project will use a trans-disciplinary framework of social and developmental psychology and media and communications and the innovative methods of the First Person Perspective and Digital Ethnography to address existing - gaps in research into the use of Information Communication Technologies, child development and family communication. Commenting upon research in the field, the recent report www.eukidsonline noted a prevalence of studies based on quantitative methods - and a neglect of focus on mobile, convergent and emerging technologies. It also identified a persistent focus on risks and harm rather than opportunities and benefits and the lack of information on the role of adults, safety mediation and their - effectiveness. This project fills these gaps by: (1) capturing the actual practices of adolescents with ICTs; (2) understanding how ICTs, family communication and parenting mutually shape one another; (3) exploring the opportunities and risks of ICTs - for family and child development and the role of parents as safety mediators. A minimum of ten families with at least one adolescent child aged 13-16 will be recruited through Italian secondary schools to participate in the research which will - involve data gathering via micro cameras (subcams) and video-interviews. Our innovative methods will provide new knowledge on: parents’ and adolescents’ individual and interpersonal practices in relation to ICTs; the goals, motives, representations - and emotions underlying these practices and ICTs mediation processes in everyday family life. The implications of ICTs use for families and children’s health will also be considered. The results will be disseminated to socio-educational and clinical - agencies, policy makers, and the general public. The fellowship will be hosted by the Department of Social Psychology at the London School of Economics and Political Science, a pioneer in Digital Ethnography and co-supervised by the Department of - Media and Communications. - - 2017-08-31, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - AdoDigitFamX - - - H2020-MSCA-IF-2014 - - - 660743 - - - - - UNIVERSITAT DE BARCELONA - - - EUR 158 121,60 - - - Collective Phenomena in dense Active Matter: phase transitions and non-equilibrium dynamics. - - - EUR 158 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - The overall aim of the research activities presented in this proposal is to elucidate the general principles governing the physics of many-body systems of active particles when excluded-volume interactions compete with - internal driving forces. We aim to reach a general understanding of this novel class of “active materials” and give an answer to the following question: How are the structure of the liquid and solid phases, and their mechanical response to an applied - deformation, affected by self-propulsion? Statistical mechanics can efficiently deal with a broad class of soft matter systems at thermal equilibrium. However, active matter evolves in a non-equilibrium manner, as it is made of elements which have - their own source of motion, which demands a new conceptual framework to describe it. By combining numerical simulations and theoretical analysis of model systems, we intend to get new quantitative predictions that can be tested experimentally in - suspensions of self-propelled colloids, active emulsions or dense assemblies of cells, and exploit our results to design and characterise novel materials through collaboration with experimental groups. The completion of this programme will represent - a major contribution into this fast-growing field with direct applications in materials science and biophysics: the engineering of synthetic materials that mimic the behaviour of living matter is a major challenge of current science and technology. - - 2017-07-14, closed project | - - - 2015-07-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - COLPHAM - - - H2020-MSCA-IF-2014 - - - 657517 - - - - - UNIVERSITAT DE BARCELONA - - - EUR 158 121,60 - - - The fate of black holes in high-energy physics -- exploring their dynamical instabilities - - - EUR 158 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - Humankind has always been on a quest to uncover the secrets of our universe and "detect the inmost force that binds the world and guides its course". We intend to take important steps towards a more profound understanding of - nature's mysteries by employing black holes (BHs). - - 2018-09-28, ongoing project - - - 2016-09-29 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - BHstabNL - - - H2020-MSCA-IF-2014 - - - 655360 - - - - - UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK - - - EUR 187 866 - - - Decoding Stress Resilience - - - EUR 187 866 - - - Ireland - - - Higher or Secondary Education Establishments - - Stress is a common feature of our lives yet some people respond to stress better than others, a concept known as resilience. There is a growing body of experimental data which has implicated several brain structures and - molecular mechanisms. However to date there has been limited focus on the bed nucleus of the stria terminalis (BNST) and the mechanisms in this brain region which could be involved. One of several proteins expressed by the BNST, which is a key - regulator of the stress response, is the pituitary adenylate cyclase-activating peptide (PACAP). But the expression of PACAP is under the control of stress-responsive nucleotides called miRNAs. Thus, there exists a complex system in the BNST which - regulates the stress-response and hypothetically could be involved in mediating resilience. To test this hypothesis, the DE-STRESS project will conduct a series of experiments with the objectives of (i) determining whether PACAP expression in the - BNST is different in states of resilience and susceptibility, (ii) identifying miRNAs that are differentially expressed in these states and which regulate PACAP expression and (iii) elucidating their functional effects on the stress response. Hence, - the DE-STRESS project uses an innovative approach to decode the concept of stress resilience and will advance understanding of the pathophysiology of stress-induced disorders. Additional objectives of the project include dissemination and transfer of - knowledge to relevant stakeholders, forming collaborations within academia and industry with a view to commercialising research findings as well as develop project management and career development skills of the applicant. In line with the Work - Programme for the MSCA fellowships, the knowledge and competencies gained by the applicant will add to developing his potential to achieve professional maturity and leadership in the field so that he may continue to make significant contributions to - society and the economy. - - 2018-06-30, ongoing project - - - 2016-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Ireland - - - DE-STRESS - - - H2020-MSCA-IF-2015 - - - 704995 - - - - - FUNDACIO INSTITUT DE RECERCA DE L'ENERGIA DE CATALUNYA - - - EUR 170 121,60 - - - Micro-Solid Oxide Fuel Cells based on highly catalytic ceramic oxide thin films nanostructures - - - EUR 170 121,60 - - - Spain - - - Research Organisations - - Solid Oxide Fuel Cells (SOFCs) are one of the most efficient and fuel flexible power generators. However, a great limitation on their applicability in portable devices arises from long start up times involving high energy - consumption. A recent revolution based on the integration of SOFCs in mainstream silicon technology allows overcoming these drawbacks while opening new avenues for the use of fuel cells as uninterrupted power generators in mobile applications such as - consumer electronics. Starting from the most recent breakthroughs of the hosting group, the Micro-SOLUTION project will be focused on improving the performance of µSOFCs at high temperatures (≥700 ºC) by developing thin film full-ceramic electrode - materials with high catalytic activity. To achieve this goal, surface decoration of highly stable thin film nanostructured electrodes will be carried out. Further integration of the optimized electrodes in μSOFC cells will bring power densities above - 500mW/cm2. The inter/multidisciplinary approach proposed in the Micro-SOLUTION project will allow the researcher acquiring new skills in Key Enabling Technologies such as nano- and micro-technology. Moreover, two different secondments in the - Institute of Microelectronics of Barcelona and the company FAE will complement the researcher’s training giving him a multisectoral point of view and a clear idea of transfer knowledge activities in the field of Solid Oxide Fuel Cells. Therefore, - planned research and training activities in the Micro-SOLUTION project will re-enforce a position of professional maturity in research and will provide the researcher new career perspectives. - - 2017-06-30, closed project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - Micro-SOLUTION - - - H2020-MSCA-IF-2014 - - - 659270 - - - - - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - - - EUR 1 508 821,75 - - - Constrained Democracy: Citizens’ Responses to Limited Political Choice in the European Union - - - EUR 1 508 821,75 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - National governments operate under the growing constraints of European integration that limit the choices they can offer citizens and the policy instruments they can use. Yet, despite the centrality of political choice to the - functioning of electoral democracy, we know very little about the consequences of constrained political choices for citizens’ engagement in democratic processes. Across Europe, an increasing number of citizens are supporting extreme parties or - declining to take part in democratic elections. This project offers the first systematic examination of how the range and substance of political choices offered to citizens in the EU shape democratic perceptions and electoral behaviour. Understanding - how citizens perceive and react to the growing constraints on domestic politics is crucial to a diagnosis of European democracy and for an evidence-based debate on reform of EU institutions. Building on the Principal Investigator’s award-winning - research on electoral democracy and extensive experience of designing and analysing cross-national surveys and experiments, this project is a pioneering study of the consequences of constrained democracy. It uniquely combines a large-N cross-national - analysis of citizens’ responses to mainstream party convergence and case studies of the ‘emergency politics’ of the Eurozone crisis with micro-level experimental work. This project aims to transform the study of citizens’ democratic attitudes and - behaviour by focusing on the importance of political choice. By developing and testing a theoretical model of heterogeneous citizen responses to the constrained political choice, the project provides insights into why citizens turn against mainstream - parties or exit democratic processes altogether. This further allows EUDEMOS to develop proposals for how institutions can be designed to facilitate citizens’ participation in and satisfaction with democratic processes in a multi-level European - Union. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - EUDEMOS - - - ERC-2014-CoG - - - 647835 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 185 076 - - - Aryl amide metallofoldamersas selective saccharide sensors - - - EUR 185 076 - - - France - - - Research Organisations - - Carbohydrate recognition is fundamental in varied biological processes such as cellular differentiation, cell–cell interactions, immune defence and inflammatory response; consequently it plays key roles in tumour growth and - metastasis, adhesion of viruses and bacteria to host cells and in immune and inflammatory disorders. - - 2018-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - RAMSES - - - H2020-MSCA-IF-2015 - - - 707071 - - - - - UNIVERSITAT DE BARCELONA - - - EUR 170 121,60 - - - Rotational effects on strongly gravitating systems with matter - - - EUR 170 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - Black holes (BHs), where gravity is strongest in the universe, are the objects where we must confront the most extreme phenomena predicted by general relativity (GR) and extensions thereof. As for the majority of astrophysical - bodies, BHs are typically spinning. However, addressing rotation in GR is notoriously difficult. Moreover, BHs are ‘dirty’: they are accompanied by clouds of gas or accretion disks, which introduce deviations from the known vacuum solutions. The - complexity of the Einstein equations, taking into account the presence of matter and the rotation of spacetime, hampers attempts to model realistic BHs. - - 2017-09-30, closed project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - REGMat - - - H2020-MSCA-IF-2014 - - - 656882 - - - - - UNIVERSITAT DE VALENCIA - - - EUR 170 121,60 - - - Tuning of 2D materials properties through controlled functionalization with opto-electroactive complexes - - - EUR 170 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - Ultrathin two-dimensional nanosheets of layered transition metal dichalcogenides (TMDCs) are the fascinating materials for several applications in electronics, opto-electronics, spintronics, sensing, catalysis, energy storage - and conversion, to name a few. The fields have witnessed huge attention world-wide in recent years. In spite of advancement of the 2D materials, there is a lack of proper chemical functionalization. Therefore, apposite functionalization of TMDCs to - tune electronic charge and spin properties beyond current systems is extremely crucial. Herein, we propose chemical functionalization of 2D-TMDCs by optical and electroactive functional terpyridyl (tpy) complexes. The functional terpyridyl complexes - offer numerous advantages including (i) much more robustness due to strong metal-to-ligand back bonding through [dπ(M)-pπ(L)] as compared to the organic ligands, (ii) versatile coordination modes, (iii) tunable, and reversible redox properties, and - (iv) switchable metal-to-ligand charge-transfer (MLCT) band in the visible region. Through this functionalization we will be able to: - - - 2019-01-15, ongoing project - - - 2017-01-16 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - Terpy2DMat - - - H2020-MSCA-IF-2015 - - - 706238 - - - - - DOKUZ EYLUL UNIVERSITESI - - - EUR 145 845,60 - - - DEVELOPMENT OF A HIGH PERFORMANCE FLOWING ELECTROLYTE-DIRECT METHANOL FUEL CELL STACK THROUGH MODELING AND EXPERIMENTAL STUDIES - - - EUR 145 845,60 - - - Turkey - - - Higher or Secondary Education Establishments - - Flowing electrolyte-direct methanol fuel cell (FE-DMFC) is a novel energy technology in which the performance of the conventional DMFC is increased by eliminating the methanol crossover problem. There are some studies found in - the literature to predict the performance of this fuel cell using one and two-dimensional single phase models. The validation of these models was done using the experimental test results for the membrane electrode assemblies (MEA) built with - conventional materials. In this project, the main objective is to develop a high performance FE-DMFC stack through modeling and experimental studies. For this purpose, a three-dimensional and two-phase multiphysics model, which includes all the - transport phenomena in all the layers, will be developed to predict the performance of the FE-DMFC stack accurately. To validate this model, a FE-DMFC stack based on alternative MEA materials (i.e. materials having lower cost, and higher stability - and reaction kinetics) will be manufactured in-house in cooperation with the partner organization in Europe. After validating this model, the effect of significant design and operating parameters of the stack on the output parameters will be - investigated; thus the parameters that increase the performance of this fuel cell mostly will be determined. This project will have have a very positive impact in Dr. Colpan's career as it will help him to develop lasting integration with his - institution and increase his network in Europe. The knowledge and results gained as a result of the research conducted during this project will be shared with other researchers, scientists, and general public through several activities (e.g. - conference, seminar, and papers in the journals, webpage, and visiting schools). It is expected that the results of this project will make a significant progress toward commercialization of the FE-DMFC, which in turn contributes to the economy and - social prosperity of European society. - - 2017-08-31, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Turkey - - - FEDMFC - - - H2020-MSCA-IF-2014 - - - 661579 - - - - - UNIVERSITAT DE BARCELONA - - - EUR 170 121,60 - - - A novel isotope tool to assess nanoparticle toxicity in wetland plants - - - EUR 170 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - Nanoparticles (NPs), metal particles of less than 100nm, are increasingly emitted to the environment from a variety of anthropogenic sources. However, their toxic effects on living organisms, capacity to enter the food chain, - and impact in environmental health are poorly understood. NANOREM is a research project aiming to provide the first comprehensive insight into the toxicity of zinc oxide (ZnO) nanoparticles in wetland plants. This information is essential to evaluate - correctly the risk of releasing large quantities of NPs to the environment. In this project we will make use of cutting edge isotope techniques to trace the sources of NP pollution, and to understand how NPs might change the current paradigm of metal - cycling and assimilation by plants. Furthermore, NPs will be synthesized from plants and plant extracts using novel methods, and fully characterized. - - 2018-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - NANOREM - - - H2020-MSCA-IF-2015 - - - 704957 - - - - - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - - - EUR 1 276 880 - - - Multinationals, Institutions and Innovation in Europe - - - EUR 1 276 880 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Multinational Enterprises (MNEs) are key ‘tectonic forces’, shaping the ‘mountains’ in a far-from-flat world economic geography. In 2010, MNEs generated value added for approximately US$16 trillion accounting for more than a - quarter of world GDP (UNCTAD, 2012). The progessive expansion of firms from emerging economies into multinational enterprises is unprecedented. Outflows of FDIs from developing economies reached the record level of $426 billion in 2012, corresponding - to 31% of global outflows, up from 16% in 2007 (UNCTAD, 2013). - - - 2020-05-31, ongoing project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - MASSIVE - - - ERC-2014-STG - - - 639633 - - - - - UNIVERSITAT DE BARCELONA - - - EUR 158 121,60 - - - Fast Thermalization of the Quark-Gluon Plasma - - - EUR 158 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - Understanding the properties of extreme phases of nuclear matter created in relativistic heavy ion collisions is one of the major challenges in theoretical physics. Matter under such extreme conditions was present in the very - early universe and is nowadays produced in relativistic heavy ion collisions. In this proposal we address two questions that are central to the understanding of the very early stages of such collisions from the perspective of both strongly and weakly - coupled field theory: What is the time-scale of the thermalization and why does it happen so fast? - - 2017-08-31, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - FastTh - - - H2020-MSCA-IF-2014 - - - 658574 - - - - - UNIVERSITAT DE VALENCIA - UNIVERSITAT DE VALENCIA - - - EUR 1 716 954 - - - Statistical Learning for Earth Observation Data Analysis. - - - EUR 1 716 954 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - SEDAL is an interdisciplinary project that aims to develop novel statistical learning methods to analyze Earth Observation (EO) satellite data. In the last decade, machine learning models have helped to monitor land, oceans, - and atmosphere through the analysis and estimation of climate and biophysical parameters. Current approaches, however, cannot deal efficiently with the particular characteristics of remote sensing data. In the coming few years, this problem will - largely increase: several satellite missions, such as the operational EU Copernicus Sentinels, will be launched, and we will face the urgent need to process and understand huge amounts of complex, heterogeneous, multisource, and structured data to - monitor the rapid changes already occurring in our Planet. - - 2020-08-31, ongoing project | - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Spain - - - SEDAL - - - ERC-2014-CoG - - - 647423 - - - - - UNIVERSITAT DE BARCELONA - UNIVERSITAT DE BARCELONA - THE UNIVERSITY OF SUSSEX - - - EUR 1 495 753 - - - Women travelling to seek abortion care in Europe: the impact of barriers to legal abortion on women living in countries with ostensibly liberal abortion laws - - - EUR 1 495 753 - - - Spain - Spain - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In many European countries with ostensibly liberal abortion laws, women face legal restrictions to abortion beyond the first trimester of pregnancy, as well as other barriers to legal abortion, in particular shortages of - providers willing and able to offer abortion due to poor training and to conscientious objection among physicians. The Council of Europe has recognized that conscientious objection can make access to safe abortion more difficult or impossible, - particularly in rural areas and for low income women, who are forced to travel far to seek abortion care, including abroad. The WHO also highlights that delaying abortion care increases risks for women’s reproductive health. Despite the relevance of - this topic from a public health and human rights perspective, the impact of procedural and social barriers to legal abortion on women in countries with ostensibly liberal abortion laws has not been studied by social scientists in Europe. This - five-year research project is envisaged as a ground-breaking multi-disciplinary, mixed-methods investigation that will fill this gap, by capitalizing on previous, pioneer anthropological research of the PI on abortion and conscientious objection. It - will contribute to the anthropology of reproduction in Europe, and particularly to the existing literature on abortion, conscientious objection and the medicalization of reproduction, and to the international debate on gender inequalities and - citizenship, by exploring how barriers to legal abortion are constructed and how women embody and challenge them in different countries, by travelling or seeking illegal abortion, as well as their conceptualizations of abortion and their self - perception as moral/political subjects. The project will be carried out in France, Italy and Spain, where the few existing studies show that women face several barriers to legal abortion as well as in the UK, the Netherlands and Spain, where Italian - and French women travel to seek abortion care. - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Spain - - - BAR2LEGAB - - - ERC-2015-STG - - - 680004 - - - - - KATHOLIEKE UNIVERSITEIT LEUVEN - KATHOLIEKE UNIVERSITEIT LEUVEN - STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS - - - EUR 2 000 000 - - - Cancer treatment during pregnancy: from fetal safety to maternal efficacy - - - EUR 2 000 000 - - - Belgium - Belgium - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - The evolution in drug regulation of the last 50 years has left pregnant women and their fetuses orphaned. This is particularly problematic for cancer during pregnancy, which raises a difficult and conflicting medical ethical - decision process and which has recently become increasingly frequent. In 2012 we published the first prospective study indicating that antenatal exposure to cancer treatment can overall be considered safe. Building on this proof of concept, the - current proposal wants to take a groundbreaking step towards developing a standard of care for cancer during pregnancy by addressing –in an integrated fashion- the challenges at the level of the fetus, the mother and the fetomaternal barrier. At the - core of this proposal lies an international registry of pregnant women with cancer, along with a registry of their children, and biobanks of maternal, placental, cord blood and tumoral tissues. Research track ‘child’ aims to deliver robust evidence - of fetal safety. Research track ‘mother’ aims to address the emerging concerns in the oncological management of the mother, and specifically, the possible distinct biology of pregnancy-associated breast cancer, the most frequent cancer type in - pregnancy. The research approach includes large-scale clinical follow-up studies along with laboratory studies on patient biomaterials, including pharmacological investigations and RNA-sequencing studies. Complementary to these studies is research - track ‘placenta’ in which cutting-edge models of human placental research are used to address the poorly understood physiological basis of the placental barrier function in this specific situation. This ambitious program will rely on a - multidisciplinary team of experts. Not only may the scientific deliverables of this proposal constitute a major step forward to the well-being of both mother and fetus in a pregnancy complicated by cancer, the methodological approach may also provide - critical impetus to further research in this field. - - 2020-09-30, ongoing project | - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Belgium - - - CRADLE - - - ERC-2014-CoG - - - 647047 - - - - - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - - - EUR 1 294 699 - - - Designing Effective Public Policies - - - EUR 1 294 699 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This proposal outlines a number of projects in public economics, with links to other fields such as macro, real estate, labor, and gender economics. The projects evolve around several large administrative datasets from the UK - and Denmark, and they advance approaches and methodologies that have recently been developed in public economics into new areas. There is a strong public policy focus running through the proposal, including tax policy, transfer policy, family policy, - and indirectly monetary policy. The objective is to achieve a comprehensive understanding of how government interventions affect two key markets: the housing market and the labor market. - - 2021-05-31, Grant Agreement terminated - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - DEPP - - - ERC-2015-CoG - - - 681696 - - - - - UNIVERSITAT DE BARCELONA - UNIVERSITAT DE BARCELONA - - - EUR 2 138 825 - - - A New Strategy for Gravity and Black Holes - - - EUR 2 138 825 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - General Relativity (GR) encompasses a huge variety of physical phenomena, from the collision of astrophysical black holes, to the dynamics (via holography) of strongly-coupled plasmas and the spontaneous symmetry-breaking in - superconductors. Black holes play a central role in all this. However, their equations are exceedingly hard to solve. The apparent lack of a generic tunable parameter that allows to solve the theory perturbatively (like the electric coupling constant - in electrodynamics, or the rank of the gauge group in large-N Yang-Mills theory) is arguably the single most important obstacle for generic efficient approaches to the physics of strong gravity and black holes. I argue that one natural parameter - suggests itself: GR can be defined in an arbitrary number of dimensions D. Recently I have demonstrated that the limit of large D is optimally tailored for the investigation of black holes, classical and potentially also quantum. Explicit preliminary - studies have proved that the concept is sound, powerful, and applicable even in four dimensions. - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Spain - - - GravBHs - - - ERC-2015-AdG - - - 692951 - - - - - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - - - EUR 1 662 942 - - - Bayesian Peer Influence: Group Beliefs, Polarisation and Segregation - - - EUR 1 662 942 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The objective of this research agenda is to provide a new framework to model and analyze dynamics of group beliefs, in order to study phenomena such as group polarization, segregation and inter-group discrimination. We - introduce a simple new heuristic, the Bayesian Peer Influence heuristic (BPI), which is based on rational foundations and captures how individuals are influenced by others' beliefs. We will explore the theoretical properties of this heuristic, and - apply the model to analyze the implications of belief dynamics on social interactions. - - - 2021-07-31, ongoing project - - - 2016-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - BPI - - - ERC-2015-CoG - - - 681579 - - - - - UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK - UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK - - - EUR 990 087 - - - Creative Agency and Religious Minorities: ‘hidden galleries’ in the secret police archives in 20th Century Central and Eastern Europe - - - EUR 990 087 - - - Ireland - Ireland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project concerns the creative agency of religious minorities in the transformation of Central and Eastern Europe societies in the 20th century. It constitutes the first comparative research on the secret police archives - in the region from the perspective of the history and anthropology of religion and offers a radical perspectival shift on the value and uses of the secret police archives away from questions of justice and truth to questions of creative agency and - cultural patrimony. Interdisciplinary in nature it combines archival, anthropological and cultural studies approaches to provide a re-examination and re-contextualization of the holdings of secret police archives in three states; Romania, Moldova and - Hungary. The secret police archives, in addition to containing millions of files on individuals monitored by the state, also constitute a hidden repository of confiscated religious art and publications of religious minorities that were persecuted in - the 20th century under fascism and communism. The investigation of these materials will be complemented by ethnographic research and the impact of the research will be extended through a public exhibition of previously hidden materials. The project - has three principal stages: 1) copy/retrieve and catalogue examples of this creative material from the archives; 2) engage in ethnographic research with the communities that produced this material in order to explore the meaning and power of these - artistic creations at the time of their production and in the context of post-socialism; 3) curate and stage a touring exhibition that re-presents the narratives and experiences of religious groups through their own artistic creations in order to - conduct research in real time on questions of religious pluralism and intolerance in contemporary society. Through these three steps, this project will shed fresh light on the role that minority religious groups played in challenging the hegemonic - order and in extending pluralism. - - 2020-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Ireland - - - Hidden Galleries - - - ERC-2015-STG - - - 677355 - - - - - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - - - EUR 1 257 242,51 - - - Research on Macroeconomic Fluctuations and Trade - - - EUR 1 257 242,51 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The proposal is divided into three strands whose main goals are to i) study macroeconomic fluctuations, ii) identify the mechanisms that drive and propagate these fluctuations, and iii) use the empirical findings to inform and - formulate models that can be used for quantitative policy and positive analysis. - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - MACROTRADE - - - ERC-2015-CoG - - - 681664 - - - - - STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS - STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS - - - EUR 1 500 000 - - - From haplotype to phenotype: a systems integration of allelic variation, chromatin state and 3D genome data - - - EUR 1 500 000 - - - Netherlands - Netherlands - - - Research Organisations - Research Organisations - - High-throughput sequencing methods are breaching the barrier of $1000 per genome. This means that it will become feasible to sequence the genomes of many individual and create a deep catalog of the bulk of human genetic - variation. A great task will lie in assigning function to all this genetic variation. Genome wide association studies have already shown that 40% of all loci significantly associated with disease are found in intergenic, supposedly regulatory - regions. One of the current challenges in human genetics is that variants that affect expression on a single allele cannot be directly linked, because only have genotype information, rather then haplotype information. The overarching aim of the - project is to resolve haplotypes in order to identify genetic variants that affect gene expression. We will do this in three sub-projects. In the first main project we will use 3D genome information gathered from Hi-C experiments to haplotype the - genomes of six lymphoblastoid cell lines. We will integrate these data with chromatin profiling and RNAseq data in order to build integrative models for the prediction of gene expression and the effect of genetic variation on gene expression. In the - second project we will perform haplotyping the breast cancer genes BRCA1/2 in a large cohort of individuals that come from families with a high-risk of hereditary breast cancer. Allelic imbalance in BRCA1/2 expression levels are known to be - associated with an increased risk for breast cancer. We will aim to find genetic variants that are associated with a decreased allelic expression of BRCA1/2 to improve breast cancer risk assessment. Finally, we will develop a novel tool to study 3D - genome organization of single alleles, which will allow us to identify how individual alleles are organized in the nucleus and identify multi-way interactions (i.e. involving more than two genomic loci). With this we hope to better understand how - complex 3D organization contributes to gene regulation. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - HAP-PHEN - - - ERC-2014-STG - - - 637587 - - - - - Fundació Institut de Recerca Contra la Leucemia Josep Carreras - Fundació Institut de Recerca Contra la Leucemia Josep Carreras - - - EUR 2 000 000 - - - GENOMIC, CELLULAR AND DEVELOPMENTAL RECONSTRUCTION OFINFANT MLL-AF4+ ACUTE LYMPHOBLASTIC LEUKEMIA - - - EUR 2 000 000 - - - Spain - Spain - - - Research Organisations - Research Organisations - - Infant cancer is very distinct to adult cancer and it is progressively seen as a developmental disease. An intriguing infant cancer is the t(4;11) acute lymphoblastic leukemia (ALL) characterized by the hallmark rearrangement - MLL-AF4 (MA4), and associated with dismal prognosis. The 100% concordance in twins and its prenatal onset suggest an extremely rapid disease progression. Many key issues remain elusive: - - - 2020-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Spain - - - INFANTLEUKEMIA - - - ERC-2014-CoG - - - 646903 - - - - - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - - - EUR 1 992 442,51 - - - Narrative Ordering and Explanation in the Sciences: Historical Investigations and Perspectives - - - EUR 1 992 442,51 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The aim of this project is to understand the role of narrative in modern science. Narratives have appeared in many places in the human, social and natural sciences over the past two centuries. They can be found both in - accounts of real situations and in simulations of virtual situations, in empirical work and in theorizing. It is clear that narratives have played important roles for scientists well beyond the simple act of reporting. Yet we lack an account of what - kinds of thing scientists know from using narrative and how such ‘narrative knowing’ is constituted. Indeed, with the notable exceptions of medicine and evolutionary biology, even the study of those field narratives, as narratives, has been largely - ignored by both historians of science and narrative scholars. - - 2020-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - NARRATIVENSCIENCE - - - ERC-2015-AdG - - - 694732 - - - - - MARTIN-LUTHER-UNIVERSITAET HALLE-WITTENBERG - - - EUR 236 210,40 - - - The Dynamics of Solidarity on Madagascar: An Ethnography of Political Conflicts and Appeasement Strategies in the Context of a Pronounced Consens Norm - - - EUR 236 210,40 - - - Germany - - - Higher or Secondary Education Establishments - - The aim of this anthropological research project is to improve understanding of the peace-making processes operating in the ongoing Malagasy political crisis. A dispute in 2009 over the Malagasy presidency, the most powerful - political position on the island, marked the beginning of a particularly difficult period. At first tensions were limited to the national political level, but the situation rapidly degenerated into a more general social crisis as international - support was suspended, the economy plummeted down and the population of about 22 million had to cope with great insecurity. - - 2019-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Germany - - - DySoMa - - - H2020-MSCA-IF-2015 - - - 702497 - - - - - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - - - EUR 1 049 855 - - - Labour market dynamics and optimal policies - - - EUR 1 049 855 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - From pension reforms to UI extensions, the optimal tax and program design literature is often ill-equipped to provide clear guidance in policy debates on the reform of social insurance and tax-and-benefit systems. The reason - is that this literature is mostly focused on static settings, while these programs are inherently dynamic: they specify a schedule of tax and benefits that is time or state dependent and they affect individuals’ decisions throughout their lifetime. - - - 2021-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - DYNAMICSS - - - ERC-2015-STG - - - 679704 - - - - - UNIVERSITAT DE BARCELONA - UNIVERSITAT DE BARCELONA - INSTITUTE OF POLITICAL ECONOMY AND GOVERNANCE - - - EUR 2 500 000 - - - The Birth of Party Democracy. The Emergence of Mass Parties and the Choice of Electoral Laws in Europe and North America (1870-1940) - - - EUR 2 500 000 - - - Spain - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - The project will develop a theoretically-based account of the emergence of mass parties, the choice of electoral institutions, and the final crystallization of different party systems in Europe and North America during the - emergence of mass democracy and the formation of modern parties (1870-1940). It will combine statistical and historical methods to explain the formation of diverse party systems as the outcome of political choices made at particular critical - junctures that involved the creation of nonsocialist and socialist parties, the mobilization of their corresponding electorates, and the strategic response of ppolitical elites (often through the manipulation of electoral laws and sometimes through - the creation of new electoral coalitions). - - 2021-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Spain - - - partydemocracy - - - ERC-2015-AdG - - - 694318 - - - - - UNIWERSYTET MARII CURIE-SKLODOWSKIEJ - - - EUR 245 361,60 - - - Effect of water and wastewater treatment on the properties of engineered nanomaterials (ENMs) in context of their fate, toxicity and interaction with other contaminants - - - EUR 245 361,60 - - - Poland - - - Higher or Secondary Education Establishments - - The primary goal of this study is to use the state-of-the-art methods to study the changes of engineered nanomaterials (ENMs) during water and wastewater treatment and to evaluate how these changes will affect ENMs fate, - toxicity and interaction with other contaminants. - - - 2020-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Poland - - - SAFEnano - - - H2020-MSCA-IF-2015 - - - 699794 - - - - - STICHTING VU - UNIVERSITY OF YORK - MAGYAR TUDOMANYOS AKADEMIA TERMESZETTUDOMANYI KUTATOKOZPONT - UNIVERSITAT DE BARCELONA - VERNALIS (R&D) LIMITED - ZOBIO BV - BEACTICA AB - Novartis Pharma AG - - - EUR 3 842 481,96 - - - FRAGments training NETwork - - - EUR 3 842 481,96 - - - Netherlands - United Kingdom - Hungary - Spain - United Kingdom - Netherlands - Sweden - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The promise of more efficient lead discovery is fuelling the enthusiasm for fragment-based lead discovery (FBLD). In this approach, highly sensitive biochemical and biophysical screening technologies are being used to detect - the low affinity binding of low molecular weight compounds (the so-called fragments) to protein targets that are involved in pathophysiological processes. By investigating the molecular interactions between fragment hit(s) and the target protein, a - detailed understanding of the binding event is obtained. This enables the rational and efficient optimisation of the hit fragment. The optimised compounds represent high quality leads for drug development. The necessary FBLD technologies and - approaches have emerged mainly from small and specialised biotech companies. At present, FBLD is being adopted throughout pharmaceutical sciences, including by pharmaceutical companies, SMEs and academic research groups. So far, the necessary - training that is needed to obtain an holistic view of the possibilities and opportunities that FBLD provides is missing, most likely because the highly multidisciplinary nature of the FBLD work is difficult to capture within one (academic) institute. - Therefore, we have established FragNet as a dedicated FBLD training network. The consortium consists of the most prominent pharmaceutical companies, biotech companies and academic groups that have jointly shaped the FBLD research area. FragNet is - committed to train 15 ESRs in all facets of FBLD using the combined technologies, skills and knowledge. This will include both research (e.g., technologies on the interface of chemistry and biology) and transferable skill sets (e.g., writing, media - training, entrepreneurship and thorough understanding of scientific knowledge transfer). This will enable the ESRs to excel in today’s drug discovery and chemical biology programmes that are performed in public and private organisations in the - pharmaceutical sciences. - - 2020-02-29, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Netherlands - - - FRAGNET - - - H2020-MSCA-ITN-2015 - - - 675899 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - JOHANNES GUTENBERG-UNIVERSITAT MAINZ - UNIVERSITAT DE BARCELONA - UNILEVER RESEARCH AND DEVELOPMENT VLAARDINGEN BV - CORDOUAN TECHNOLOGIES SAS - UNIVERSITAT WIEN - FORSCHUNGSZENTRUM JULICH GMBH - FREIE UNIVERSITAET BERLIN - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 3 899 357,64 - - - TRANSPORT OF SOFT MATTER AT THE NANOSCALE - - - EUR 3 899 357,64 - - - United Kingdom - France - Germany - Spain - Netherlands - France - Austria - Germany - Germany - United Kingdom - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - We propose a Multi-Partner ITN-ETN network on Transport of Soft Matter at the Nanoscale. The scientific topic, which is the focus of the proposal, is an emerging field of science and technology. Challenges such as design of - environmentally friendly engineering materials or understanding the principles of biological organization crucially depend on fundamental understanding of transport of fluids and colloids at the nanoscale. Topics we will study within NANOTRANS are at - the core of modern technology (i.e. active design of “smart” nanomaterials, nanofluidic and “lab on a chip” devices, sustainable nanocompounds, energy storage, contaminants dissemination in environment, oil recovery, drug delivery and disease - treatment). - - - 2020-02-29, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - NANOTRANS - - - H2020-MSCA-ITN-2015 - - - 674979 - - - - - FUNDACIO INSTITUT DE RECERCA DE L'ENERGIA DE CATALUNYA - UNIVERSITAT POLITECNICA DE CATALUNYA - TECHNISCHE UNIVERSITEIT DELFT - VLAAMSE INSTELLING VOOR TECHNOLOGISCH ONDERZOEK N.V. - ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA - UNIVERSITE JOSEPH FOURIER GRENOBLE 1 - UNIVERSITE GRENOBLE ALPES - GENERAL ELECTRIC DEUTSCHLAND HOLDING GMBH - EFACEC ENERGIA - MAQUINAS E EQUIPAMENTOS ELECTRICOS SA - - - EUR 3 527 433 - - - Innovative controls for renewable sources Integration into smart energy systems - - - EUR 3 527 433 - - - Spain - Spain - Netherlands - Belgium - Italy - France - France - Germany - Portugal - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The continuous increase of the share of renewable energy sources is redefining the electrical networks. In future infrastructures, an important number of agents (sources, storage devices and consumers) will have intelligent - interfaces allowing the regulation of the injection and extraction of power into the grid. This context will create multiple alternatives to increase the efficiency in electricity generation and consumption, to reduce energy costs and to provide a - more reliable operation of electrical grids. These future networks will be only possible with suitable control algorithms. INCITE is a multi-sectoral consortium gathering experts on control and power systems, from academia and industry with the - purpose of providing innovative control solutions for the future electrical networks. - - 2019-11-30, ongoing project - - - 2015-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Spain - - - INCITE - - - H2020-MSCA-ITN-2015 - - - 675318 - - - - - UNIVERSITAT DE BARCELONA - - - EUR 242 683,20 - - - Using the halo model to maximise the information gain from forthcoming weak-lensing surveys. - - - EUR 242 683,20 - - - Spain - - - Higher or Secondary Education Establishments - - The mechanism behind the current phase of accelerated expansion of the Universe is not understood. Either space is filled with dark energy, a substance that has never been detected in an earth-bound laboratory, or the - gravitational equations of Einstein are incorrect and acceleration arises naturally within the correct theory. There are now a wide variety of models that purport to explain accelerated expansion, and often these models make different predictions for - how matter is clustered in the Universe. Weak gravitational lensing uses measurements of the deflection of light from distant galaxies to infer the intervening distribution of matter, and thus allows us to discriminate between acceleration models. - However, in its present state the lack of accurate modelling for the distribution of matter as a function of cosmological paradigm will be the major limitation in the interpretation of forthcoming weak lensing data: the goal of the 'halo modelling' - project is to provide the required accuracy of modelling. To achieve this, the Fellow will take a novel hybrid approach; combining results from perturbation theory, high-accuracy simulations and semi-analytics. Crucially, the 'halo modelling' project - will simultaneously improve our understanding of the distribution of baryons relative to dark matter in the Universe, and incorporate this. The current ignorance of the level of mass redistribution caused by baryonic feedback processes has the - potential to severely degrade the constraining power of forthcoming lensing surveys. - - 2020-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Spain - - - Halo modelling - - - H2020-MSCA-IF-2015 - - - 702971 - - - - - FUNDACIO INSTITUT DE RECERCA DE L'ENERGIA DE CATALUNYA - FUNDACIO INSTITUT DE RECERCA DE L'ENERGIA DE CATALUNYA - - - EUR 1 841 387 - - - Breaking the temperature limits of Solid Oxide Fuel Cells: Towards a newfamily of ultra-thin portable power sources - - - EUR 1 841 387 - - - Spain - Spain - - - Research Organisations - Research Organisations - - Solid Oxide Fuel Cells (SOFCs) are one of the most efficient and fuel flexible power generators. However, a great limitation on their applicability arises from temperature restrictions. Operation approaching room temperature - (RT) is forbidden by the limited performance of known electrolytes and cathodes while typical high temperatures (HT) avoid their implementation in portable applications where quick start ups with low energy consumption are required. - - - 2021-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Spain - - - ULTRA-SOFC - - - ERC-2015-CoG - - - 681146 - - - - - UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA - UNIVERSIDADE DO MINHO - UNIVERSITAT DE VALENCIA - TECHNISCHE UNIVERSITAET MUENCHEN - KATHOLIEKE UNIVERSITEIT LEUVEN - UNIVERSITAT WIEN - THE UNIVERSITY OF NOTTINGHAM - Asociacion - Centro de Investigacion Cooperativa en Nanociencias - CIC NANOGUNE - GRAPHENEA SA - UNIVERSIDADE DE AVEIRO - - - EUR 2 962 661 - - - Redesigning 2D Materials for the Formulation of Semiconducting Inks - - - EUR 2 962 661 - - - Spain - Portugal - Spain - Germany - Belgium - Austria - United Kingdom - Spain - Spain - Portugal - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - 2D-INK is targeted at developing inks of novel 2D semiconducting materials for low-cost large-area fabrication processes on insulating substrates through a new methodology, which will exceed the properties of state-of-the-art - graphene- and graphene oxide based inks. Achieving this would represent an important step forward in the processing of 2D semiconducting materials and will provide the key parameters for fabricating the next generation of ultrathin electronic - appliances. - - 2018-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-1-2014 - FET-Open research projects - - - RIA - Research and Innovation action - - - Spain - - - 2D-INK - - - H2020-FETOPEN-2014-2015-RIA - - - 664878 - - - - - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - - - EUR 1 568 276 - - - New perspectives on inflation - - - EUR 1 568 276 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The research in this proposal will contribute to our knowledge of the dynamics and effects of inflation through the perspective of risk-adjusted inflation and valuation formulas. The goal is to provide new perspectives on - inflation and its impact on resource constraints. - - 2021-06-30, ongoing project - - - 2016-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - INFL - - - ERC-2015-CoG - - - 682288 - - - - - UNIVERSITY OF DURHAM - UNIVERSITY OF DURHAM - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - UNIVERSITA CA' FOSCARI VENEZIA - - - EUR 2 092 125 - - - Knowledge For Use [K4U]: Making the Most of Social Science to Build Better Policies - - - EUR 2 092 125 - - - United Kingdom - United Kingdom - United Kingdom - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - ‘Research is an investment in our future’ says Horizon 2020. That’s only true if you know what to do with it. When it comes to social policy, we don’t really know how to put our research results to use. K4U aims to remedy - this. K4U will construct a radically new picture of how to use social science to build better social policies. This picture will be founded on an ambitious philosophical study of the technology of social science including a thorough - reconceptualisation of objectivity, deliberation and the role of values in the science/society interface. Current work, primarily by the evidence-based policy and practice movement, focusses on knowledge production: encouraging high quality studies - and vetting them. Little attention goes to knowledge use: How is social science knowledge to be used in policy design and deliberation – how should it be used so that policy outcomes are more effective and more reliably predictable and competing - values and points of view are respected in policy choice and implementation? - - - 2020-10-31, ongoing project | - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - K4U - - - ERC-2014-ADG - - - 667526 - - - - - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - - - EUR 1 287 755 - - - Market Beliefs and Optimal Policy in the Presence of Disasters - - - EUR 1 287 755 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - My proposal consists of two strands linked by a common theme--namely a concern for the impact of disasters, in financial markets and more generally--and by a shared methodology. - - 2020-04-30, ongoing project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - Disasters - - - ERC-2014-STG - - - 639744 - - - - - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - Fundació Institut de Recerca Contra la Leucemia Josep Carreras - KAROLINSKA INSTITUTET - UNIVERSITAT ROVIRA I VIRGILI - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH - BIOBAM BIOINFORMATICS SL - CHRONOS THERAPEUTICS LIMITED - 4SC DISCOVERY GMBH - NESTLE INSTITUTE OF HEALTH SCIENCES SA - - - EUR 3 825 128,16 - - - Chromatin and MetabolismChromatin-metabolism interactions as targets for healthy living - - - EUR 3 825 128,16 - - - Germany - Spain - Sweden - Spain - France - Germany - United Kingdom - Germany - Spain - United Kingdom - Germany - Switzerland - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Metabolic disorders are at pandemic levels. Based on recent estimates, ~50% of Europeans are overweight, 20% are obese and 10% have type II diabetes. Obesity and insulin resistance impact European health to the tune of €110 - billion per year. These disorders have genetic, nutritional and lifestyle causes. However, the molecular mechanisms that link nutrients and lifestyle to gene activity and chromatin are poorly understood, and drug targets are only starting to be - identified. Pioneering experiments by ChroMe labs now reveal how sugars, exercise, the gut microbiome and novel drugs regulate chromatin. These novel links promise to substantially improve our understanding and treatment of metabolic disorders. - National governments and the EU invest major resources to address the burden of the “metabolic syndrome”. However, there is an urgent need for expert human capital able to dissect metabolic diseases, exploit new targets and establish innovative - therapies. No local nor international program currently provides adequate training at this emerging interface of chromatin and metabolism. - - - 2020-02-29, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - ChroMe - - - H2020-MSCA-ITN-2015 - - - 675610 - - - - - UNIVERSITAT DE BARCELONA - UNIVERSITAT DE BARCELONA - CONSIGLIO NAZIONALE DELLE RICERCHE - - - EUR 2 400 000 - - - Testing the role of Mediterranean thermohaline circulation as a sensor of transient climate events and shaker of North Atlantic Circulation - - - EUR 2 400 000 - - - Spain - Spain - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - The Mediterranean Sea is an excellent sensor of transient climate conditions at different time scales. Changes in Mediterranean water properties result from complex interactions between the Atlantic inflow, local climate and - north and south atmospheric teleconnections. In turn, Mediterranean outflow waters spill into the Atlantic Ocean, thus acting as a net salt and heat source for the Atlantic Meridional Overturning Circulation (AMOC). Climate models anticipate changes - in these circulation systems within decades; thus it becomes critical to understand the natural range of variations in the Mediterranean Thermohaline Circulation (MedTHC) and whether these can alter the AMOC. An innovative approach, based on both - well-established and newly-developed analytical methods will be applied to characterize, qualitatively and quantitatively, past changes in the MedTHC dynamics. Specific time windows representing very different transient periods (18-14 ka BP; 9.5-6.5 - ka BP and the last 2 kyr) will be targeted in order to understand the distinctive role that individual forcing mechanisms exerted in controlling MedTHC changes. Particular emphasis will be placed on building robust regional chronologies and proxy - records with unprecedented high-resolution. This approach will combine proxy data from sediment cores and deep-sea corals along the main paths of water masses as they cross the Mediterranean basins and exit into the North Atlantic. This paleo-data - analysis will be complemented with novel climate model paleo-simulations to test the sensitivity of the AMOC to changes in Mediterranean outflow under varying AMOC conditions. The main goals are to identify: (1) the natural range of MedTHC - variability; (2) the forcings and inter-regional teleconnections driving MedTHC changes; (3) the associated impact onto the AMOC. The assessment of the forcings controlling MedTHC and the ensuing impact on the AMOC will allow us to gauge the - consequences of future Mediterranean changes. - - 2021-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Spain - - - TIMED - - - ERC-2015-CoG - - - 683237 - - - - - STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS - STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS - - - EUR 2 497 125 - - - Genomics of Chromosome Architecture and Dynamics in Single Cells - - - EUR 2 497 125 - - - Netherlands - Netherlands - - - Research Organisations - Research Organisations - - The spatial architecture of mammalian interphase chromosomes, each consisting of tens of megabases of DNA, poses an intriguing topological problem and is relevant for various nuclear functions. A major challenge is that - chromosome architecture exhibits substantial stochastic cell-to-cell variation. To unravel the principles of chromosome organization, new single-cell genome-wide approaches that capture the intrinsic variability are needed. - - 2022-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Netherlands - - - GoCADiSC - - - ERC-2015-AdG - - - 694466 - - - - - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - - - EUR 1 217 313,76 - - - INDIVIDUAL ACTION THROUGH SOCIAL ORGANIZATIONS: THE CASE OF POVERTY - - - EUR 1 217 313,76 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - There is arguably a lack of research on organizations with social goals in management. For an extreme case, i.e., of poverty, Prahalad (2006) described compelling examples of innovative organizations in South Asia, which he - suggested served the poor. However, very little is known about: 1) What factors ‘cause’ social organizations, for instance, in settings of extreme poverty, to grow and scale up ‘successfully,’ and how and why?, and 2) What organizational factors - influence ‘social performance’ for target groups, and how and why, and under which conditions (where and when), and for whom? Building on insights from our earlier theoretical and empirical work on networks, leadership, and learning, as well as our - extensive pilot studies in India, we will explore how and why social organizations grow and scale up, in relation to social outcomes for relevant target groups, using mixed methods (a qualitative phase followed by a quantitative phase, to first build - and then test theory). We propose to study organizations in an extreme setting, where arguably, social problems are worst: of poverty in South Asia, and picked the education sector given its potential importance for enabling people to move out of - poverty. We believe that a better understanding of how and why organizations scale up successfully to enable target groups in poverty to be more proactive is also relevant from a practical perspective. It is for instance at the heart of the new - Sustainable Development Goals, and it is our hope to make a contribution into this direction. - - 2020-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - IATSO - - - ERC-2015-AdG - - - 695524 - - - - - UNIVERSITAT DE VALENCIA - - - EUR 170 121,60 - - - Long Range Surface Plasmon Polaritons as an Alternative Information Carrier for Nanoscale Quantum Circuitry - - - EUR 170 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - The aim of this innovative and high-impact interdisciplinary proposal is to investigate the potential properties and applications of plasmonic metallic nanostructures that enable the confinement of light to scales beyond the - diffraction limit, known as quantum plasmonics. Latest studies have revealed the quantization of surface plasmon polaritons (SPPs). It could be the stepping stone for the generation of miniaturized photonic components for the quantum control of - light. This implies that the SPPs would represent a totally new sort of information carrier for nanoscale circuitry, enabling a revolutionary bridge between current diffraction-limited microphotonics and bandwith-limited nanoelectronics, paving the - way for integrated quantum information processing. Thus, in a first stage we will develop integrated nanoscale quantum plasmonics building blocks on-a-chip, such as efficient single-photon sources or transistors, which is the component required for - the fabrication of true nanoscale quantum computing logic gates. We also plan to exploit the low-Ohmic-losses and prospects for large scale production of ultra-compact cutting-edge graphene plasmonic circuits. This research will be lastly applied to - single molecule sensing. Experiments will be performed using innovative techniques for nanofabrication of photonic nanostructures and for characterization. The expected results will allow taking advantage of quantum interference effects, setting up - the optical response of the extremely low losses Long Range (LR) SPPs modes within a quantum framework and showing that graphene layers produce strong light-matter interaction and extreme optical field confinement. The results will be compared with - ab initio simulations, giving a precise and consistent experimental and theoretical panorama of quantum plasmonics. - - 2018-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - Spain - - - QuP - - - H2020-MSCA-IF-2015 - - - 704998 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSITY OF LEEDS - CONSIGLIO NAZIONALE DELLE RICERCHE - UNIVERSITE PARIS-SUD - UNIVERSITAET REGENSBURG - - - EUR 2 798 445 - - - Ultrashort Pulse Generation from Terahertz Quantum Cascade Lasers - - - EUR 2 798 445 - - - France - United Kingdom - Italy - France - Germany - - - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The generation of ultrafast and intense light pulses is an underpinning technology across the electromagnetic spectrum enabling the study of fundamental light-matter interactions, as well as industrial exploitation in a - plethora of applications across the physical, chemical and biological sciences. A benchmark system for such studies is the modelocked Ti:Sapphire laser, which has grown from being a laboratory curiosity to an essential tool in a broad range of - application sectors. Beyond Ti:Sapphire systems, there have been impressive developments in semiconductor based devices for pulse generation in the optical range. These benefit from low system costs and are an enabling technology in new application - domains including high speed communications. - - 2018-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-1-2014 - FET-Open research projects - - - RIA - Research and Innovation action - - - France - - - ULTRAQCL - - - H2020-FETOPEN-2014-2015-RIA - - - 665158 - - - - - FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA - UNIVERSITE PARIS-SUD - UNIVERSITAT DE BARCELONA - ALACRIS THERANOSTICS GMBH - AB ANALITICA SRL - - - EUR 2 906 801,25 - - - PROtein SEQuencing using Optical single molecule real-time detection - - - EUR 2 906 801,25 - - - Italy - France - Spain - Germany - Italy - - - Research Organisations - Chiara Andreoli - Tel.: +3901071781854 - Fax: +39 010 7170817 - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The advent of analytical techniques with extremely low limits of detection has led to dramatic progresses mostly in the field of nucleic acids sequencing. Despite the advent of the next generation sequencing platforms, the - current genome sequencing task remains formidable, and revolutionary advances in DNA sequencing technology are still demanded. Nevertheless, the primary actors in virtually all life processes are the proteins coded by DNA sequences known as genes. - Proteins can yield far more compelling revelations than may be gleaned from DNA alone. Protein sequencing may radically transform patient treatment, enabling precise monitoring of disease response to therapeutics at the molecular level. - Single-molecule sequencing of proteins is of enormous value, offering the potential to detect diminishingly small quantities of proteins that may have been altered by alternative splicing or post-translational modification. In this project, we build - upon current state-of-the-art sequencing technologies to develop novel proof-of-principle technologies for high-throughput protein sequencing and single molecule DNA/RNA sequencing. The work proposed herein will provide: (i) a new sequencing - technology development that utilizes plasmonic nanostructures in order to enhance the optical detection and to control the molecules movement by means of optical trapping; (ii) a novel approach of plasmonic based optical spectroscopy for sequencing - of protein; (iii), a rigorous analytical model to reconstruct the exact sequence from the signals recorded; and (iv) a plasmonic device that can perform both nucleic acids and amino-acids sequencing in one functional unit. These research efforts - provide a foundation for the novel use of systems for a wide range of applications, such as the framework to investigate next generation protein sequencing, as well as high-throughput DNA sequencing and genetic diagnostics. - - 2019-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-1-2014 - FET-Open research projects - - - RIA - Research and Innovation action - - - Italy - - - PROSEQO - - - H2020-FETOPEN-2014-2015-RIA - - - 687089 - - - - - WELSH ASSEMBLY GOVERNMENT - - - EUR 9 558 000 - - - Strengthening International Research Capacity in Wales - - - EUR 19 116 000 - - - United Kingdom - - - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - Scientists in Wales are efficient, productive, collaborative, impactful and in many cases world leading. Recent evidence shows scientific excellence but a lack of critical mass in areas most likely to drive a knowledge economy - through innovation and translation. This application forms the foundation of the 'Sêr Cymru (Stars Wales) II Programme' designed to produce a step change in Welsh scientific capacity, building on excellence and investing in early career researchers. - This integrated proposal marries Marie Skłodowska-Curie COFUND fellowships with European Structural Funds, university, industrial and Welsh Government funding to bring in 140 new fellowships (90 via SIRCIW) in strategic areas including clinical - science, engineering, physics, mathematics and applied Social Sciences. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2014-FP - Marie Skłodowska-Curie Co-funding of regional, national and international programmes (COFUND-FP) - - - MSCA-COFUND-FP - Fellowship programmes - - - United Kingdom - - - SIRCIW - - - H2020-MSCA-COFUND-2014 - - - 663830 - - - - - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - - - EUR 1 275 043,75 - - - Information Technology and Institutions Supporting Human Capital Accumulation and Exchange - - - EUR 1 275 043,75 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Information technology revolutions transform the production and exchange of ideas and drive profound institutional and cultural change. History provides unique settings to document the causal impact of changes in information - technology and institutions, and the best evidence on their long-run effects. - - 2020-04-30, ongoing project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - INFO TECHNOLOGY - - - ERC-2014-STG - - - 638957 - - - - - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY - UNIVERSITAET BAYREUTH - HUMBOLDT-UNIVERSITAET ZU BERLIN - TECHNISCHE UNIVERSITEIT EINDHOVEN - NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO - INNOVATIONLAB GMBH - UNIVERSITE DE FRIBOURG - UNIVERSITY OF CYPRUS - UNIVERSITAT DE VALENCIA - - - EUR 3 870 919,80 - - - Interfaces in opto-electronic thin film multilayer devices - - - EUR 3 870 919,80 - - - United Kingdom - United Kingdom - Israel - Germany - Germany - Netherlands - Netherlands - Germany - Switzerland - Cyprus - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Development of new materials over the past decade paved the way for organic/hybrid electronics into commercial applications. Now, perfection of material interfaces in organic/hybrid thin-film devices is key to drive the - technology further and enable new, more advanced applications. INFORM offers a paradigm shift from focusing on materials to focusing on devices by probing, modelling and controlling relevant processes that take place at interfaces, e.g. charge - transfer, injection and collection. By training researchers in this exciting, highly multidisciplinary area, INFORM contributes to the need for skilled, knowledgeable researchers in the field of multilayer thin-film devices in Europe. INFORM will - generate fundamental insights and apply them to improve the performance and reliability of relevant devices that will allow INFORM’s industrial partners to grow their markets and take full advantage of the low-temperature, low-cost and large-area - processing potential of new generation semiconductors. The challenges are wide-ranging and thus require a cross-European, multidisciplinary, intersectorial and multifaceted approach. The INFORM network consists of partners with complementary skills - and toolboxes, including 9 academic groups fully equipped, experienced and knowledgeable in multilayer device research and supervision. The involvement of 4 non-academic partners at the highest level, through supervision of 2 ESRs and secondments, - ensures ESR exposure to the industrial workplace and simultaneously provides benefits to the non-academic partners. Complementary training activities in personal skills (e.g writing and communicating), is given by a specialist partner. The - combination of high level research and intense training endows the ESRs with multidisciplinary know-how and hands-on skills for careers that impact not only the field of multilayer devices, but also the broader quests for renewable energy resources - and development of nanotechnology. - - 2019-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - INFORM - - - H2020-MSCA-ITN-2015 - - - 675867 - - - - - THE UNIVERSITY OF EXETER - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - PLATFORM KINETICS LIMITED - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - UNIVERSITAT DE BARCELONA - - - EUR 2 978 882,50 - - - Magnetically actuated bio-inspired metamaterials - - - EUR 2 978 882,69 - - - United Kingdom - United Kingdom - United Kingdom - France - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - - This project will deliver a new class of metamaterials whose functionality can be controlled by external magnetic fields. The materials consist of micromotors, comprising an anisotropically “hard” and “soft” ferromagnetic - particle pair embedded in a polymer matrix, and promise wide-ranging technological applications. The project, involves 5 partners with expertise in experimental and theoretical physics, biological science and technology. Building upon a detailed - analysis of the physical properties of the individual motors, and their dependency on their magnetic and material properties, the team will develop methods for incorporating the motors into elastic membranes (MEMs). We shall analyse the mechanical - and optical properties of these constructs and the ways in which they can be modulated by the external magnetic fields. These novel properties will then be used to produce prototype devices: - - - 2018-10-31, ongoing project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-1-2014 - FET-Open research projects - - - RIA - Research and Innovation action - - - United Kingdom - - - ABIOMATER - - - H2020-FETOPEN-2014-2015-RIA - - - 665440 - - - - - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - - - EUR 195 454,80 - - - Identity Management on Social Media by Diasporic LGBTQs - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The internet, and social media in particular, create new opportunities and pose new challenges for the ways people think about themselves as well as manage the expressions of their identities. In this research project I aim to - enrich our knowledge about the transformations of identity in the new media landscape of the early XXI century by investigating those transformations from the perspective of diasporic LGBTQs, that is, lesbian, gay, bisexual, transgender and queer - people. I will focus on the latest theories on social media and identity about 1) fixating the fragmented self (van Zoonen 2013), 2) collapsed contexts (boyd 2011) and 3) the multiplication of contexts (Papacharissi 2011), by investigating those - phenomena from the perspective of Polish post-accession immigrants to the UK. I will examine what diasporic LGBTQs and their social media’s uses can teach us about the relationship between the internet and identity, as well as what opportunities and - difficulties social media create to a group that faces different challenges of exclusion and discrimination. I will first use a quantitative survey to map the diversity of social media used by Polish LGBTQs in the UK. However, because I am primarily - interested in meanings of daily media practices, it is qualitative methods, and in-depth interviews in particular, which will form the core of my methodological toolkit. At the same time, to trigger more and better quality data I will combine - traditional qualitative methods with such innovative approaches as think-aloud protocols (which require from participants to talk about the activity in which they are involved) and digital methods (the methods of the medium under scrutiny). - - 2018-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - FACELOOK - - - H2020-MSCA-IF-2015 - - - 699745 - - - - - UNIVERSITAT DE BARCELONA - - - EUR 158 121,60 - - - Innovation Systems in Financial Crisis: Technological Dynamics, Industrial Structure and Business Cycles - - - EUR 158 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - This research project will investigate from an empirical, theoretical and normative perspective the impact of financial crisis on innovation systems, and in particular knowledge networks and technology clusters, and by - extension, on technological trajectories, industrial dynamics and economic growth of afflicted EU economies. It will also explore the latent link between technological dynamics and business cycles, and examine to what extent a strategic mix of RTDI, - industrial and regional policies can address structural causes of crises and foment techno-economic development by building the capacities of innovation systems and bridging the technology gap. - - - 2017-06-30, closed project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - Spain - - - cRISys - - - H2020-MSCA-IF-2014 - - - 659530 - - - - - UNIVERSITAT DE VALENCIA - - - EUR 158 121,60 - - - Remotely quantifying vegetation productivity: exploiting sun-induced fluorescence-photosynthesis relationships through field and modelling methods - - - EUR 158 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - During the past few years airborne/spaceborne detection and quantification of sun-induced chlorophyll fluorescence (SIF) emitted by terrestrial vegetation became possible at several narrow wavelengths. These improvements in - Earth Observation technology offer huge possibilities to increase our knowledge on the basic functioning of the Earth’s vegetation, i.e. the photosynthetic process of plants resulting in atmospheric carbon uptake. However, still some efforts are - required for establishing well-funded relationships between SIF and photosynthesis under different plant physiological states. Hence, in order to improve the quantification of photosynthesis through SIF, the main aim of this proposal (FLUOPHOT) is to - further establish the link between the SIF characteristics and both the actual and potential photosynthesis of the plant. This will be achieved by coupling dedicated field/laboratory measurements and campaigns with modelling activities. As a result - of the planned activities, significant progress is foreseen in the remote quantification of vegetation productivity. FLUOPHOT strives to unravel fundamental SIF-photosynthesis systems at the leaf and canopy scale. These findings are in direct support - of ESA’s candidate Earth Explorer mission FLEX, and eventually will lead to unbiased global estimates of photosynthetic carbon uptake. - - 2018-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - FLUOPHOT - - - H2020-MSCA-IF-2015 - - - 701815 - - - - - STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS - STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS - - - EUR 149 500 - - - Exploiting vulnerabilities in protein synthesis for cancer diagnosis and therapy - - - EUR 149 500 - - - Netherlands - Netherlands - - - Research Organisations - Research Organisations - - Tumor growth requires continuous synthesis of proteins, nucleic acids and lipids that are important components of the cell. Demand for amino acids as the building blocks for protein synthesis in rapidly dividing tumor cells is - often much higher than that of normal cells. Such increased demand can represent a vulnerability of the tumor. Importantly, this vulnerability is already being exploited for therapy in one instance: Addition of L-asparginase - an enzyme lowering the - concentration of the amino acid asparagine in blood - to chemotherapy against acute lymphoblastic leukemia, resulted in a dramatic increase in cure from 5% to 95% of patients treated. Recent scientific publications highlight the fact that tumors are - often metabolically rewired, and multiple examples of altered amino acid demand and/or turnover have been demonstrated in different cancer indications. Multiple drugs are under development that target amino acid availability, uptake or biosynthesis. - - 2016-10-31, closed project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2014 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Netherlands - - - Diricore - - - ERC-2014-PoC - - - 665317 - - - - - UNIVERSITAT DE BARCELONA - - - EUR 170 121,60 - - - Combinatorics in Transcendental Dynamics - - - EUR 170 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - Complex dynamics studies the evolution of a complex manifold under the action of a holomorphic map. In this proposal we study the dynamical systems generated by transcendental (either entire or meromorphic) maps acting on the - complex plane. By using a wide range of classic and new techniques, we investigates epecially the combinatorics of these maps: that is to say, we build relations between the dynamics of the transcendental map on some specific subset of the complex - plane and the dynamics of the shift map on the space of infinite sequences over the integers. Combinatorics in this setting is a powerful tool to understand the dynamics of transcendental maps and to understand the structure of specific families of - transcendental maps. The study of combinatorics for transcendental maps is also likely to offer new insights in the combinatorics for rational maps and possibly in other areas of complex dynamical systems, like the systems generated by the iteration - of holomorphic maps on manifolds with more than one complex dimension. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - CoTraDy - - - H2020-MSCA-IF-2015 - - - 703269 - - - - - UNIVERSITAT DE BARCELONA - - - EUR 158 121,60 - - - Cosmology with future large-scale surveys - - - EUR 158 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - New challenges for large galaxy surveys: - - 2018-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Spain - - - COSMOFLAGS - - - H2020-MSCA-IF-2015 - - - 706896 - - - - - STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS - - - EUR 165 598,80 - - - Breaking down arenavirus cell entry - - - EUR 165 598,80 - - - Netherlands - - - Research Organisations - - Hemorrhagic fever viruses are serious human threats for which we don’t have adequate treatments available, which is painfully highlighted by the current Ebola virus outbreak in Western Africa. These viruses are obligatory - intracellular parasites that make use of the host machinery at every phase of their infection cycle. Virus attachment and entry are the initial steps, which requires engagement of a viral glycoprotein with a cell surface receptor. This interaction - then triggers internalization of the virus particle via a Trojan horse-like vesicular pathway, eventually resulting in the release of the viral genome into the cytoplasm of the target cell. We have recently shown that cell entry of at least some - hemorrhagic fever viruses (i.e. Ebola virus and Lassa virus) is even more sophisticated, as it requires triggered-recognition of an intracellular receptor as an unexpected additional step. A precise understanding of how these major pathogens enter - cells is required to reveal the mechanisms by which they cause disease. In this application, I will combine targeted engineering of viral systems with a genomics approach that enables crystal-clear, yeast-like genetics in human cells. Focusing on - arenaviruses, these genome-wide surveys will reveal host factors indicative of virus entry tactics never observed before. I will use biochemistry, microscopy, and cell biological assays to examine in detail the virus-host interplay with these factors - and will identify promising new antiviral targets for arenavirus family members that cause human disease. Overall, I foresee that this project will provide a much-needed window on the unique cell entry strategies of these lethal pathogens, which thus - far revealed a surprising diversity in the biological host networks being hijacked to establish infection. - - 2017-09-30, closed project | - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Netherlands - - - BRACE - - - H2020-MSCA-IF-2014 - - - 660417 - - - - - UNIVERSITY OF NEWCASTLE UPON TYNE - UNIVERSIDAD DE LLEIDA - UNIVERSITAT DE VALENCIA - UNIVERSITEIT VAN AMSTERDAM - RIJKSUNIVERSITEIT GRONINGEN - - - EUR 1 044 000 - - - Cultural Narratives of Crisis and Renewal - - - EUR 1 044 000 - - - United Kingdom - Spain - Spain - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The objective of the “Cultural Narratives of Crisis and Renewal” project is to examine cultural production and cultural practices in periods of societal crisis at the turn-of the 20th Century on both sides of the Atlantic. The - overarching aim of the project is to investigate the role of cultural production, not just as a vehicle to elaborate cohesive narratives in moments of crisis, but as a space to create alternative imaginaries for social renewal. We need to explore the - changing nature of our societies and the reconfiguration of regional and/or national cultural landscapes into globalized real (and virtual) spaces that erode the cultural frontiers of the nation-state. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - United Kingdom - - - CRIC - - - H2020-MSCA-RISE-2014 - - - 645666 - - - - - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - - - EUR 183 454,80 - - - Organisational public engagement with science and society (OPEST) - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - There is a widely entertained, societal obligation on the part of scientific institutions to serve society with social impact and to engage citizens in research policy. This is also evidenced in recent policy documents (e.g. - the European Union Framework Programme for Research and Innovation defines tackling societal challenges through research as one of the main priorities for Europe in the next decade), and by procedures of research funding bodies that require plans for - engaging society with the results of the funded research. As a result, universities and scientific institutions face an imperative to facilitate ‘pathways to impact’ for their research as this can be an important factor in determining funding beyond - serving society. While research on resources for PE has mainly focused on scientists, little attention has been paid to the institutional context in which PE occurs. OPEST – Organisational Public Engagement with Science and Technology will examine - how RIs are engaging society. We aim to assemble an international database of comparable data on the culture of PE at institutions and to develop PE indicators for assessing institutional PE. The study has been implemented in Portugal in 2014. This - project will allow conducting the study in the UK, Germany, Italy, Netherlands and the US. - - - 2018-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - OPEST - - - H2020-MSCA-IF-2015 - - - 708434 - - - - - FORSCHUNGSVERBUND BERLIN EV - UNIVERSITAT DE VALENCIA - UNIVERSITEIT TWENTE - CONSIGLIO NAZIONALE DELLE RICERCHE - UNIVERSITAET AUGSBURG - UNIVERSIDAD POLITECNICA DE MADRID - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - TOSHIBA RESEARCH EUROPE LIMITED - CHALMERS TEKNISKA HOEGSKOLA AB - - - EUR 3 855 693,24 - - - Dynamic electromechanical control of semiconductor nanostructures by acoustic fields - - - EUR 3 855 693,24 - - - Germany - Spain - Netherlands - Italy - Germany - Spain - France - United Kingdom - United Kingdom - Sweden - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - The dynamic modulation of semiconductor structures using vibrations provides a powerful tool for the control of the materials properties required for novel functionalities. Surface acoustic waves (SAWs) with GHz-frequencies - and micrometre-size wavelength can be generated using piezoelectric transducers fabricated with standard integrated circuit technology. Their small propagation velocity and high sensitivity to disturbances confined to a superficial region have long - been exploited in electronic signal processing and sensor applications. The SAW-induced modulation of the electro-optical properties of semiconductor structures is now been used for a wide range of applications including advanced sensors, the control - of chemical processes, as well as the coherent control of carriers, spins, photons, and phonons down to the single-particle level. The latter are presently been exploited for different functionalities including advanced waveguide modulators, tuneable - optical resonators, and single-electron pumps and single-photon sources. - - 2019-05-31, ongoing project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - SAWTrain - - - H2020-MSCA-ITN-2014 - - - 642688 - - - - - UNIVERSITAT ROVIRA I VIRGILI - KOZEP-EUROPAI EGYETEM - ASOCIACION GITANA DE MUJERES DROM KOTAR MESTIPEN DE BARCELONA - UNIVERSITAT DE BARCELONA - UNIVERSITAT AUTONOMA DE BARCELONA - BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY - THE UNIVERSITY OF AUCKLAND - QUEENSLAND UNIVERSITY OF TECHNOLOGY - QLD QUT - UFSCar - - - EUR 391 500 - - - Overcoming Inequalities in Schools and Learning Communities: Innovative Education for a New Century - - - EUR 499 500 - - - Spain - Hungary - Spain - Spain - Spain - United States - New Zealand - Australia - Brazil - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Overcoming Inequalities in Schools and Learning Communities: Innovative Education for a New Century (SALEACOM here after) proposes the collaboration between 7 research groups (Australia, Brazil, New Zealand, Hungary, South - Africa, Spain, USA) and 1 non academic institution (Drom Kotar Mestipen) with a global scope to address educational and social exclusion in schools and learning communities. SALEACOM seeks to create an International Research Network that has the - following aims: (i) to increase worldwide cooperation in the study of successful actions with children and youth systematically underserved; (ii) to provide high-quality training programs for teachers and educational researchers aiming at overcoming - inequalities; (iii) to develop interdisciplinary solutions for and with learners most heavily affected by inequalities, including access and quality of higher education; (iv) to design strengths-based methodologies for international comparative - research to further the impact of research on the lives of students who have been historically excluded (v) to create a global program of successful educational actions to be implemented across educational systems. To promote coherent and effective - cooperation among the research team, it accounts for the inclusion of researchers across disciplines, stages in their careers and cultures, committed to conducting strengths-based international research to further impact the lives of students who - have been traditionally unsuccessful in educational contexts. To maximise the research outcomes of this proposal, researcher exchanges are based on partners’ complementarities in skills, methodological expertise and knowledge of several excluded - populations that face similar challenges globally (i.e. Roma, Indigenous populations, African American, among others.). In parallel to developing interdisciplinary successful educational actions in schools and learning communities, we will explore - paradigms, principles and practices. - - 2017-12-31, closed project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Spain - - - SALEACOM - - - H2020-MSCA-RISE-2014 - - - 645668 - - - - - STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS - STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS - - - EUR 149 750 - - - A treatment for BRAF inhibitor resistant melanoma - - - EUR 149 750 - - - Netherlands - Netherlands - - - Research Organisations - Research Organisations - - Some 50% of human melanoma tumors have activating mutations in the BRAF gene. BRAF inhibitor drugs given either alone or in combination with MEK inhibitors have improved progression-free and overall survival in patients with - BRAF mutant metastatic melanoma. However, drug resistance invariably limits the duration of clinical benefit of such treatments and is almost always associated with re-activation of signaling through the MAP kinase pathway in the presence of drug due - to secondary mutations in the pathway. This highlights the urgent need to develop strategies to treat melanomas that have developed resistance to BRAF and/or MEK inhibitors. - - - 2017-10-31, closed project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2015 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Netherlands - - - 2MoveMate4Melanoma - - - ERC-2015-PoC - - - 712951 - - - - - UNIVERSITAT DE VALENCIA - UNIVERSITAT DE VALENCIA - - - EUR 150 000 - - - HYBRID MAGNETIC SUPERCAPACITORS - - - EUR 150 000 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The purpose of Hy-MAC is to assess both technical and economic viability of using magnetic nanocomposites based on the combination of carbon nanoforms (graphene) with magnetic nanoparticle as hybrid supercapacitors. These - hybrid magnetic materials have shown to exhibit unique supercapacitive properties, which can be significantly enhanced by application of an external magnetic field. Thus, the specific capacitance increases up to a 500% by applying an external - magnetic field. Taking advantage of these results, in this proposal we plan to fabricate and test prototype supercapacitive devices exhibiting better performances than those reported for commercial supercapacitors. - - 2017-11-30, closed project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2015 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Spain - - - Hy-MAC - - - ERC-2015-PoC - - - 713704 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA - UNIVERSITY COLLEGE LONDON - UNIVERSITAT DE BARCELONA - BEN-GURION UNIVERSITY OF THE NEGEV - STICHTING VU - UNIVERSITY OF DURHAM - MEDICAL RESEARCH INFRASTRUCTURE DEVELOPMENT AND HEALTH SERVICES FUND BY THE SHEBA MEDICAL CENTER - NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO - MOTEK MEDICAL B.V. - - - EUR 3 911 673,24 - - - Perception and Action in Complex Environments - - - EUR 3 911 673,24 - - - France - Italy - United Kingdom - Spain - Israel - Netherlands - United Kingdom - Israel - Netherlands - Netherlands - - - Research Organisations - Research Organisations - Chiara Andreoli - Tel.: +3901071781854 - Fax: +39 010 7170817 - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The PACE research and training programme sits at the interface between basic science, technology and clinics, in order to unveil how humans control and adapt their movements in complex, naturalistic environments. Such a - research agenda has major consequences for understanding how these movements are impacted by specific brain insults and how these impairments can be compensated for via new rehabilitation methods. Improving rehabilitation programmes for sensory and - motor disabilities across the lifespan is a major societal challenge in western countries and many obstacles need to be overcome. To provide but one example, with regard to eye-hand coordination of upper limb movement remaining abilities are rarely - assessed in stroke patients or sensory-disabled children and this impacts both prognostic estimation and rehabilitation. New technologies, such as robotics or virtual reality, provide an exciting change in perspective to transfer state-of-the-art - knowledge from basic research on sensorimotor transformation into the clinical domain. To meet these societal challenges, it is crucial to train a new generation of early-stage researchers in a programme such as PACE where fundamental and - applied/clinical research are effectively integrated via collaborative research, doctoral secondments and theoretical courses – in other words, one in which clinicians, neuroscientists, theoreticians and engineers can contribute around a well-defined - problem: how humans acquire, lose and recover movement performance. With 8 academic, 1 clinical and 1 private beneficiaries, and 5 partner organizations (4 industrial, 1 in science communication), PACE structures a training and research programme - that is both highly interdisciplinary and intersectoral. Our goal is to meet both fundamental and clinical well-identified challenges as well as preparing young scientists for future european research & development in the fields of human movement - studies and rehabilitation medicine. - - 2019-03-31, ongoing project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - France - - - PACE - - - H2020-MSCA-ITN-2014 - - - 642961 - - - - - LINKOPINGS UNIVERSITET - THE UNIVERSITY OF SHEFFIELD - RANPLAN WIRELESS NETWORK DESIGN LTD - IQUADRAT INFORMATICA SL - - - EUR 634 500 - - - Deploying High Capacity Dense Small Cell Heterogeneous Networks - - - EUR 634 500 - - - Sweden - United Kingdom - United Kingdom - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Broadband mobile networks are experiencing exponential traffic growth. It is predicted that this trend will continue in the next five to ten years with an estimated compound annual growth rate of 0.6 to 1.0. Hence the traffic - (mostly data) carried by a mobile operator’s network in 2022 could be over 1000 times of that in 2012. This traffic growth presents a huge challenge to both the mobile industry and to academic researchers. - - 2019-07-31, ongoing project - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Sweden - - - DECADE - - - H2020-MSCA-RISE-2014 - - - 645705 - - - - - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - BUNDESANSTALT FUER GEOWISSENSCHAFTEN UND ROHSTOFFE - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - THE UNIVERSITY OF READING - STIFTELSEN NORSAR - UNIVERSITA DEGLI STUDI DI FIRENZE - DEUTSCHES ZENTRUM FUER LUFT - UND RAUMFAHRT EV - KONINKLIJK NEDERLANDS METEOROLOGISCH INSTITUUT-KNMI - LEIBNIZ-INSTITUT FUR ATMOSPHARENPHYSIK EV AN DER UNIVERSITAT ROSTOCK - ANDOYA SPACE CENTER AS - INSTITUTET FOR RYMDFYSIK - NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU - USTAV FYZIKY ATMOSFERY AV CR, v.v.i. - Euro-Mediterranean Seismological Centre - UNIVERSITE DE LA REUNION - UNIVERSITAET BERN - TEL AVIV UNIVERSITY - NATIONAL UNIVERSITY OF IRELAND MAYNOOTH - VEDURSTOFA ISLANDS - UNIVERSITY OF ANTANANARIVO - INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA PAMANTULUI - FUNDACAO GASPAR FRUTUOSO - CENTRE NATIONAL DE LA CARTOGRAPHIEET DE LA TELEDETECTION - - - EUR 2 985 250 - - - Atmospheric dynamics Research InfraStructure in Europe - - - EUR 3 242 382,50 - - - France - Germany - France - United Kingdom - Norway - Italy - Germany - Netherlands - Germany - Norway - Sweden - Norway - Czech Republic - France - France - Switzerland - Israel - Ireland - Iceland - Madagascar - Romania - Portugal - Tunisia - - - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Other - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - It has been robustly demonstrated that variations in the circulation of the middle atmosphere influence weather and climate throughout the troposphere all the way to the Earth’s surface. A key part of the coupling between the - troposphere and stratosphere occurs through the propagation and breaking of planetary-scale Rossby waves and gravity waves. Limited observation of the middle atmosphere and these waves in particular limits the ability to faithfully reproduce the - dynamics of the middle atmosphere in numerical weather prediction and climate models. ARISE2 capitalizes upon the work of the EU-funded first ARISE project combining for the first time international networks with complementary technologies such as - infrasound, lidar and airglow. This joint network provided advanced data products that started to be used as benchmarks for weather forecast models. The ARISE network also allows enhanced and detailed monitoring of other extreme events in the Earth - system such as erupting volcanoes, magnetic storms, tornadoes and tropical thunderstorms. In order to improve the ability of the network to monitor atmospheric dynamics, ARISE2 proposes to extend i) the existing network coverage in Africa and the - high latitudes, ii) the altitude range in the stratosphere and mesosphere, iii) the observation duration using routine observation modes, and to use complementary existing infrastructures and innovative instrumentations. Data will be collected over - the long term to improve weather forecasting to monthly or seasonal timescales, to monitor atmospheric extreme events and climate change. Compared to the first ARISE project, ARISE2 focuses on the link between models and observations for future - assimilation of data by operational weather forecasting models. Among the applications, ARISE2 proposes infrasound remote volcano monitoring to provide notifications to civil aviation. The data portal will provide high-quality data and advanced data - products to a wide scientific community. - - 2018-08-31, ongoing project | - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-1-2014 - Design studies - - - RIA - Research and Innovation action - - - France - - - ARISE2 - - - H2020-INFRADEV-1-2014-1 - - - 653980 - - - - - UNIVERSITAT DE BARCELONA - - - EUR 158 121,60 - - - Frobenius related invariants and singularities - - - EUR 158 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - This is a project in commutative algebra of positive characteristic, which has also many connections with algebraic geometry. The main goal of this project is to study the relations between some classes of rings that arise in - prime characteristic, F-singularities, and three specific notions. These are the symmetric signature, a new invariant defined by the Experienced Researcher in his Ph.D. thesis; the generalized Hilbert-Kunz function, a recent generalization of the - classical Hilbert-Kunz function studied intensively in prime characteristic algebra; and the FFRT property, a positive characteristic version of the notion of finite representation type, important in representation theory. As a guideline for the - future research, eight concrete problems are stated and will be investigated by the Experienced Researcher with the help of the Supervisor. The strategy to complete this task include the acquisition of new knowledge, which will be obtained, among - other things, also through the organization of weekly seminars with the collaboration of the host institution. The arguments of this project, F-singularities in particular, are important topics in commutative algebra and algebraic geometry which are - developing and growing fast in these years, especially in the USA and in Japan. As a further way to promote the development of these topics also in Europe, the Experienced Researcher and the Supervisor plan to organize a small workshop which will - take place in the host institution at the end of the fellowship. - - 2019-02-14, ongoing project - - - 2017-02-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - Frobenius - - - H2020-MSCA-IF-2015 - - - 701807 - - - - - UNIVERZITA KARLOVA - FONDAZIONE ENI ENRICO MATTEI - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - FONDATION JEAN-JACQUES LAFFONT,TOULOUSE SCIENCES ECONOMIQUES - - - EUR 2 115 000 - - - Global Excellence in Modelling of Climate and Energy - - - EUR 2 115 000 - - - Czech Republic - Italy - United Kingdom - United Kingdom - France - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - The global GEMCLIME project focuses on major aspects of energy economics and climate change, which is a prime example of an important global and complex scientific and policy problem. GEMCLIME covers the drivers of climate - change, the examination of climate change and energy-related risks and vulnerabilities, the valuation of economic impacts of climate change mitigation and adaptation policies, and the investigation of major policy responses to global climate and - energy challenges. GEMCLIME follows an integrated approach to modelling the impacts of climate and energy policies. The analysis of drivers, impacts, and responses to climate change attributes particular attention to the economics of renewable - energies and the valuation of non-marketed goods. While GEMCLIME is focused on fundamental economic research, our results also provide support to evidence-based policy. GEMCLIME brings together both globally and regionally the most excellent - institutions and researchers with wide-ranging research experience in the context of a collaborative scheme of research exchanges and networking. The members of the consortium share their skills and knowledge from the areas of climate change, energy, - resource, health, environmental, and agricultural economics, while drawing on the expertise of participants in financial economics, applied macroeconomics, microeconomics, and econometrics. Our consortium also includes researchers and academics from - non-economic disciplines, including political scientists, sociologists, lawyers, environmental scientists, and other scientists related to climate and energy. The reciprocal transfer of knowledge between the members of the consortium is supported by - a staff exchange including senior research fellows, professors, early-career academics, and doctoral students. Our global project aims at supporting research mobility between the EU on one side, and the USA, Canada, New Zealand, Australia, South - Africa, Singapore, and Chile on the other side. - - 2020-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Czech Republic - - - GEMCLIME - - - H2020-MSCA-RISE-2015 - - - 681228 - - - - - UNIVERSITAT DE BARCELONA - - - EUR 239 191,20 - - - Contextualising psychosocial wellbeing and mental health within sociocultural dynamics - - - EUR 239 191,20 - - - Spain - - - Higher or Secondary Education Establishments - - The lack of contextualization of the science and applications of mental health is the source of a large part of its criticisms. From the lack of research on how social dynamics influence the well-being of citizens, to the gaps - in research and coordinated implementation of different disciplines involved in mental health in a changing environment, there are still many limitations for a contextualised and integrated view. - - 2019-05-31, ongoing project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Spain - - - PSYCHOCONTEXT - - - H2020-MSCA-IF-2014 - - - 654808 - - - - - UNIVERSITAT DE BARCELONA - KOBENHAVNS UNIVERSITET - DEMOCRITUS UNIVERSITY OF THRACE - FERA SCIENCE LIMITED - - - EUR 526 500 - - - KNOWLEDGE FOR PESTICIDES CONTROL - - - EUR 526 500 - - - Spain - Denmark - Greece - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - KKNOWPEC, Knowledge for pesticides control, aims to create a transnational research network between Europe and Latin America focused on the challenge of unwanted pesticides in the environment. KNOWPEC wants to identify the - occurrence and fate of banned and toxic pesticides in drinking and natural waters in agricultural areas of Latin America where knowledge on occurrence and risk is scarce. KNOWPEC wants to assess the environmental and potential human risks of the - pesticides detected, and to provide solutions for both reducing pollution at source, and remediating contaminated water. Together, KNOWPEC will promote the sharing of knowledge at each step from pesticide analysis, toxicity and risk assessment to - advanced treatment technologies that jointly enables the design of sustainable solutions to each pesticide pollution problem. Moreover, we want to create the tools of information and networking for a source of collaboration between European and Latin - America institutions under the framework of the environmental and human protection from pesticides. - - - 2020-06-30, ongoing project - - - 2016-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Spain - - - KNOWPEC - - - H2020-MSCA-RISE-2015 - - - 690618 - - - - - UNIVERSITY COLLEGE LONDON - UNIVERSITAT DE BARCELONA - STICHTING LIBER - UNIVERSITAT WIEN - UNITED NATIONS ECONOMIC COMMISSION FOR LATIN AMERICA AND THE CARIBBEAN - - - EUR 496 582 - - - Leaders Activating Research Networks: Implementing the LERU Research Data Roadmap and Toolkit - - - EUR 496 582,50 - - - United Kingdom - Spain - Netherlands - Austria - Chile - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - We live in the age of the ‘data deluge’, where digital technology enables us to store petabytes of data and to make that available for sharing as open data. Sharing data has the potential to revolutionise the way that - researchers work. It avoids costly duplication in the collecting of data and enables research collaborations across the world which otherwise would not be possible. - - 2017-05-31, closed project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.3."> - - - INFRASUPP-7-2014 - e-Infrastructure policy development and international cooperation - - - CSA - Coordination and support action - - - United Kingdom - - - LEARN - - - H2020-INFRASUPP-2014-2 - - - 654139 - - - - - UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK - - - EUR 175 866 - - - Stilbene and entomopathogenic nematodes: Unlocking the potential - - - EUR 175 866 - - - Ireland - - - Higher or Secondary Education Establishments - - Bacteria frequently form intimate associations with a eukaryotic host where they may have critical roles in the development, behavior, and/or functions of their animal symbiont. While the underlying molecular mechanisms are - poorly understood there is increasing evidence that the bacteria are employing proteins or molecules to send signals to their host. My goal is to understand the inter-kingdom signalling that occurs between a bacterium and its animal host using, as a - model, the interaction between an entomopathogenic nematode (EPN) called Heterorhabditis and its symbiotic bacterium, Photorhabdus. - - 2018-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Ireland - - - STEPN-UP - - - H2020-MSCA-IF-2015 - - - 706272 - - - - - UNIVERSIDAD COMPLUTENSE DE MADRID - UNIVERSITAT DE VALENCIA - ASTON UNIVERSITY - POLITECHNIKA WROCLAWSKA - OPTEGRA MVZ GMBH - - - EUR 2 484 775,44 - - - European Dry Eye Network - - - EUR 2 484 775,44 - - - Spain - Spain - United Kingdom - Poland - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - EDEN is a platform for the training and career development of 10 early-stage researchers (ESRs) in Vision Sciences. It coordinates research and training collaboration among 4 leading academic institutions in Europe, providing - for a new combination of in-depth expertise from different countries. Furthermore, to strengthen the contact with the industrial world, the network has the following partners: (1) large company of hospitals, 1 SME that provides advance ophthalmic - devices for ocular examination and (2) large companies specialized in eye-care products. It emphasises experience-based training through cross-disciplinary research projects that will analyse the lacrimal functional unit with state-of-the-art - technology and assess the structural and physiological changes occurring in Dry Eye Disease (DED) patients. This will spur the generation of newer metrics to better differentiate between normal and DED patients. Further benefits include improvements - in DED diagnosis and monitoring, studies on the effect of various DED treatments, development of DED aetiology-specific treatments and exploration of the risk factors that favour development of the disease or intensify its symptoms. - - 2019-02-28, ongoing project | - - - 2015-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-EJD - Marie Skłodowska-Curie Innovative Training Networks (ITN-EJD) - - - MSCA-ITN-EJD - European Joint Doctorates - - - Spain - - - EDEN - - - H2020-MSCA-ITN-2014 - - - 642760 - - - - - UNIVERSITAT DE BARCELONA - UNIVERSITAT DE BARCELONA - - - EUR 149 950 - - - Personified Self Interaction - - - EUR 149 950 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This proof of concept is based on the ERC Advanced Grant TRAVERSE (2009-2015). It will exploit immersive virtual reality in a new form of psychological clinical intervention akin to Gestalt Therapy. The primary aim of this - Proof of Concept project is to generate a business model that would allow us to diffuse our technology to thousands of counsellors and psychologists around the world. In order to accomplish that we commission further trials to extend the evidence - base of the approach, investigate through market research the extension of the technique for business practice, develop a commercial prototype with consumer equipment that would be low cost but high quality, exhibit our product at international - conferences, and make the system available on loan to psychologists or counsellors who wished to try it, and generally start the process of diffusion. Moreover, we that our low cost system incorporates patentable inventions that would be investigated - in an IP strategy. Through this approach we will develop the Business Model and a draft Business Plan for mass take up of our applications. - - 2017-12-31, closed project - - - 2016-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2015 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Spain - - - PSI - - - ERC-2015-PoC - - - 712984 - - - - - UNIVERSITAT AUTONOMA DE BARCELONA - KUNGLIGA TEKNISKA HOEGSKOLAN - AERIS TECNOLOGÍAS AMBIENTALES S.L. - INNOVA BIC - BUSINESS INNOVATION CENTRE SRL - MERGUS PROMOTION HANDELSBOLAG - - - EUR 688 500 - - - ADVANCED MULTIFUNCTIONAL NANOSTRUCTURED MATERIALS APPLIED TO REMOVE ARSENIC IN ARGENTINIAN GROUNDWATER - - - EUR 688 500 - - - Spain - Sweden - Spain - Italy - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Daily intake of arsenic polluted water by cattle in Argentina is becoming of increasing concern, especially due to the important size of the livestock export market where EU is a main customer. Because natural forage or - alfalfa grown without irrigation is used to feed livestock, drinking water is considered the main source of arsenic for cattle (several studies reveal arsenic concentrations in phreatic water samples above 0.15 mg/L, the level that suggest causing - chronic intoxication in cattle). Therefore, as it has been demonstrated, there is a risk of exposure for the human health due to the introduction in the food chain through milk or meat. In view of arsenic toxicity and the large number of people - exposed to its effects worldwide, there is a clear need for the implementation in remote exploitations of affordable and sustainable treatment methodologies to provide potable water to cattle. To face this problem and provide a solution, NANOREMOVAS - pursues to develop and implement a pilot plant for the remote treatment of arsenic polluted waters based on the application of state-of-art advanced multifunctional nanostructured materials, already tested at the laboratory level. In this sense, - NANOREMOVAS includes the cooperation between the industry and academia of partners from Europe and Argentina. Besides the required research and innovation to demonstrate the technical and economic feasibility of the developed water recycling - technique, the seconded researchers will carry out a series of tasks and outreach activities, promoting entrepreneurship culture and support of young innovative companies in order to set-up technological partnerships within the water and livestock - sector. Furthermore, NANOREMOVAS represents a significant contribution to knowledge and technology transfer from the academia to the industrial sector, through the partners well established reputation as transfer hubs, that will led to quickly - creating designs and industrial equipment/processes/model - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Spain - - - NANOREMOVAS - - - H2020-MSCA-RISE-2014 - - - 645024 - - - - - ACADEMISCH ZIEKENHUIS LEIDEN - STICHTING INSTITUTE FOR HUMAN ORGAN AND DISEASE MODEL TECHNOLOGIES - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM - UNIVERSIDAD DE ZARAGOZA - - - EUR 520 472,50 - - - Organ on Chip in Development - - - EUR 520 472,50 - - - Netherlands - Netherlands - Germany - France - Belgium - Spain - - - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - - Organ-on-chip technology will revolutionize the healthcare domain by offering new and ground breaking solutions to different industries and especially for regenerative medicine and medication. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-03-2017 - FET-Open Coordination and Support Actions - - - CSA - Coordination and support action - - - Netherlands - - - ORCHID - - - H2020-FETOPEN-3-2017 - - - 766884 - - - - - UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK - - - EUR 1 416 000 - - - APC Postdoctoral EXcellence Programme - - - EUR 2 832 000 - - - Ireland - - - Higher or Secondary Education Establishments - - APEX (APC Postdoctoral EXcellence) is an innovative intersectoral trans- disciplinary training, career development and mobility programme based at the APC Microbiome Institute, UCC, which focuses on the research area of gut - microbiota and their role in human health and disease. APEX will offer 20 fellowships for incoming mobility with all fellows hosted in an APC academic host organisation: UCC, Teagasc, the Agriculture, Food and Development Authority (Teagasc) or the - Cork Institute of Technology (CIT). - - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2016 - Co-funding of regional, national and international programmes - - - MSCA-COFUND-FP - Fellowship programmes - - - Ireland - - - APEX - - - H2020-MSCA-COFUND-2016 - - - 754535 - - - - - EUROPEAN MOLECULAR BIOLOGY LABORATORY - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - LEIBNIZ-INSTITUT FUR PFLANZENBIOCHEMIE - UNIVERSITAT DE BARCELONA - THE UNIVERSITY OF BIRMINGHAM - CONSORZIO INTERUNIVERSITARIO RISONANZE MAGNETICHE DI METALLO PROTEINE - UNIVERSITEIT LEIDEN - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - UPPSALA UNIVERSITET - BIOBANKS AND BIOMOLECULAR RESOURCES RESEARCH INFRASTRUCTURE CONSORTIUM (BBMRI-ERIC) - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE - SWISS INSTITUTE OF BIOINFORMATICS - CENTRO DI RICERCA SVILUPPO E STUDI SUPERIORI IN SARDEGNA SOCIETA' A RESPONSABILITA' LIMITATA - - - EUR 7 697 733,75 - - - PhenoMeNal: A comprehensive and standardised e-infrastructure for analysing medical metabolic phenotype data - - - EUR 8 018 723,75 - - - Germany - United Kingdom - Germany - Spain - United Kingdom - Italy - Netherlands - United Kingdom - Sweden - Austria - France - France - Switzerland - Italy - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - - In the coming decade a significant number of the 500.000.000 European (EU/EEA) citizens will have their genome determined routinely. This will be complemented with much cheaper (currently ~20 Euro per measurement) acquisition - of the metabolome of biofluids (e.g. urine, saliva, blood plasma) which will link the genotype with metabolome data that captures the highly dynamic phenome and exposome of patients. Having such low cost solutions will enable, for the first time, the - development of a truly personalised and evidence-based medicine founded on hard scientific measurements. The exposome includes the metabolic information resulting from all the external influences on the human organism such as age, behavioural factors - like exercise and nutrition or other environmental factors. - - - 2018-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.3."> - - - EINFRA-1-2014 - Managing, preserving and computing with big research data - - - RIA - Research and Innovation action - - - Germany - - - PhenoMeNal - - - H2020-EINFRA-2014-2 - - - 654241 - - - - - UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK - - - EUR 248 063,40 - - - Photon-recycling for high-efficiency energy harvesting in GaAs photovoltaic devices on silicon - - - EUR 248 063,40 - - - Ireland - - - Higher or Secondary Education Establishments - - The Internet of Things promises billions of connected sensors and devices measuring and reporting information about the world around us. Due to the limited lifetime of batteries, this vision will not be realised without energy - harvesting solutions providing power autonomy to sensors, a topic specifically prioritised in the 2016-2017 Work programme of Horizon 2020 (page 100). This project aims to develop and demonstrate high-efficiency and low-cost GaAs photovoltaic energy - harvesters as power sources for wireless sensors, and equip the fellow with the entrepreneurial competencies required to commercialise the results. - - - 2020-06-04, ongoing project - - - 2017-06-05 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Ireland - - - RECHARGE - - - H2020-MSCA-IF-2016 - - - 746516 - - - - - SCIENCE AND TECHNOLOGY FACILITIES COUNCIL - STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS - EUROPEAN MOLECULAR BIOLOGY LABORATORY - Masarykova univerzita - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - CONSORZIO INTERUNIVERSITARIO RISONANZE MAGNETICHE DI METALLO PROTEINE - INSTRUCT ACADEMIC SERVICES LIMITED - UNIVERSITEIT UTRECHT - LUNA SAS - ISTITUTO NAZIONALE DI FISICA NUCLEARE - - - EUR 3 981 125 - - - World-wide E-infrastructure for structural biology - - - EUR 3 981 125 - - - United Kingdom - Netherlands - Germany - Czech Republic - Spain - Italy - United Kingdom - Netherlands - France - Italy - - - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Other - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - - The focus of structural biology is shifting from single macromolecules produced by simpler prokaryotic organisms, to the macromolecular machinery of higher organisms, including systems of central relevance for human health. - Structural biologists are expert in one or more techniques. They now often need to use complementary techniques in which they are less expert. Instruct supports them in using multiple experimental techniques, and visiting multiple experimental - facilities, within a single project. - - 2018-10-31, ongoing project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.3."> - - - EINFRA-9-2015 - e-Infrastructures for virtual research environments (VRE) - - - RIA - Research and Innovation action - - - United Kingdom - - - West-Life - - - H2020-EINFRA-2015-1 - - - 675858 - - - - - UNIVERSITAT DE BARCELONA - - - EUR 170 121,60 - - - Politicians’ traits and public policies: learning how personal features influence fiscal outcomes - - - EUR 170 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - Nowadays there is little doubt that maximizing social welfare is not the sole goal of policymakers. Policy choices such as the level of taxation and spending are at the core of public economics. A positive approach to this - field takes into account the fact that budgets and policies are set by political agents who are office-seekers. Early studies on political economy have focused on institutional factors, voters’ preferences, interests groups, and party ideology as - major drivers of public policies. But a growing number of theoretical and empirical studies have started to examine the particular features of political leaders (e.g. gender or ethnicity) as relevant determinants of economic outcomes and policies. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - POLITRAITS - - - H2020-MSCA-IF-2016 - - - 749547 - - - - - UNIVERSITAT DE VALENCIA - - - EUR 170 121,60 - - - Commissioning, first tests and upgrade of a high-power S-Band Radio Frequency (RF) system for R+D of high-gradient normal-conducting accelerating cavities in breakdown science and RF conditioning - - - EUR 170 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - New Radio Frequency (RF) High-Gradient (HG) knowledge and technology in normal conducting accelerator structures has been developed by the accelerator Physics community in the recent years in X-Band frequency. Significant - progress has been made to understand the RF high-gradient behavior, breakdown phenomena and cavities conditioning processes, but extensive R&D is still needed in this very interdisciplinary and phenomenology research area. This project proposes - the commissioning and upgrade of a novel high-power RF system in S-Band to perform systematic breakdown studies and conditioning of cavities in this frequency range, in particular interesting for medical applications. The main challenge is the - implementation of a hard real-time control of amplitude and phase at microsecond scale of the pulsed megawatt RF power delivered to the structures under test. The power delivery has to be done under stringent controlled and automated conditions in - order to perform the conditioning and avoid permanent damage to the structures. In addition, a power boost upgrade of the system is envisaged to reach the power limits that medical high-gradient structures need to be pushed to. A close relation with - industry partners is to be carried out in order to commission the new solid-state power modulator and test structures. The outcome of this R&D project can be crucial to make more compact linear accelerators, resulting in lower cost and size, - which can have a potential impact in several applications: hadrontherapy facilities based on linear accelerators, which will be emphasized in this project due to its advantageous features; industrial applications such as cargo scanning; or scientific - applications such as free-electron-lasers and Compton sources. - - 2019-05-18, ongoing project - - - 2017-05-19 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - HGRF-IFIC - - - H2020-MSCA-IF-2016 - - - 750871 - - - - - UNIVERSITAT DE BARCELONA - - - EUR 170 121,60 - - - Our Galaxy at full HD - - - EUR 170 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - Some astrophysical mechanisms that are crucial for the evolution of our Galaxy, and of galaxies in general, like the assemblage of the Galactic halo, the spiral arms dynamics, and the star formation processes, are poorly - understood. But this research field is on the verge of an important breakthrough thanks to the ESA Gaia mission that is gathering an unprecedented census of positions, distances, velocities and stellar properties for a billion stars. Now it is time - that the European scientists exploit their output data. Our Galaxy at full High Definition (Gal-HD) is a project that will use the Gaia data releases and follow-up surveys to investigate key galaxy evolution processes. We will do this by detecting - the signatures that they produce in the stellar phase-space of the Galaxy. Gal-HD will pioneer in: 1) the detection of Ultra Faint Dwarf Galaxies in the halo as probes for cosmological models, 2) the investigation of the large-scale kinematics of the - disk and the nature of the spiral arms, 3) the study of the nearby kinematics as tracer of the local star formation. The project combines observational and theoretical astrophysics with data mining. The Experienced Researcher (ER) has deep expertise - in Galactic dynamics, analysis of kinematic data and substructure detection tools. The Host Group is expert in Galactic astronomy, coordinates the development of the novel Gaia Archive and will train the ER on the Archive mining tools required. The - strong preparation for the Gaia exploitation of the ER and the Host Group puts them in clear advantage to make a substantial contribution to the field and to be in the front lead of the Gaia science. This research will bring the ER closer to her - long-term career goals of being a consolidated leading researcher. Gal-HD will also participate in preserving the European leadership in Galactic astronomy and space astrometry, and contribute to the Gaia scientific harvest that Europe has planned - and invested for. - - 2020-02-29, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - Gal-HD - - - H2020-MSCA-IF-2016 - - - 745617 - - - - - UNIVERSITAT DE BARCELONA - - - EUR 158 121,60 - - - Ramon Llull (1232-1316): A Vernacular Writer Between Christianity and Islam - - - EUR 158 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - Ramon Llull’s Cent noms de Déu is the only versified work which entered the net of self-quotations and self-references which Llull used to promote and advertise his own production as a new alternative to his contemporary - science and literature. In spite of his condemnation of troubadour lyric in his Book of Contemplation, Llull wrote many poems with a mnemonic-didactic purpose related to the learning of his epistemological system, i.e. the Art. Yet some his poems and - some of his literary works are strongly related with contemporary literature and literary uses which he exploited and transformed to attract a wider audience. These literary ‘traps’ were a useful tool to spread the Art among all social classes, thus - enhancing the fulfilment of Llull’s project: the conversion of all the unbelievers. The new critical edition of this work will help advancing my research on why Llull used poetic forms albeit he despised them and will provide new materials for - understanding the circulation of culture and of ideas in the Mediterranean area in the XIII-XIV centuries. - - 2019-10-01, ongoing project - - - 2017-10-02 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - Christianus Arabicus - - - H2020-MSCA-IF-2016 - - - 746221 - - - - - THE UNIVERSITY OF LIVERPOOL - UNIVERSITY OF PLYMOUTH - INNOVATION FOR AGRICULTURE - CONSIGLIO NAZIONALE DELLE RICERCHE - AINIA - BRETAGNE DEVELOPPEMENT INNOVATION - SYSTEMS RESEARCH INSTITUTE OF THE POLISH ACADEMY OF SCIENCES IBS PAN - UNIVERSITAT POLITECNICA DE VALENCIA - UNIVERSITE DE LORRAINE - UNIVERSITE TOULOUSE 1 CAPITOLE - LINKING ENVIRONMENT AND FARMING LBG - KERNOCK PARK PLANTS LIMITED - FEDERACION EMPRESARIAL DE AGROALIMENTACION DE LA COMUNIDAD VALENCIANA(FEDACOVA) - AGENZIA LUCANA DI SVILUPPO E DI INNOVAZIONE IN AGRICOLTURA - - - EUR 1 332 000 - - - Enhancing and implementing Knowledge based ICT solutions within high Risk and Uncertain Conditions for Agriculture Production Systems - - - EUR 1 332 000 - - - United Kingdom - United Kingdom - United Kingdom - Italy - Spain - France - Poland - Spain - France - France - United Kingdom - United Kingdom - Spain - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - Research Organisations - Research Organisations - Other - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - Increasingly challenging global and environmental requirements have resulted in agricultural systems coming under increasing pressure to enhance their resilience capabilities in order to respond to the abrupt changes in - resource quality, quantity and availability, especially during unexpected environmental circumstances, such as uncertain weather, pests and diseases, volatile market conditions and commodity prices. Therefore, integrated solutions are necessary to - support the whole food agricultural life-cycle value chain. Solutions necessarily must consider the products’ cycle, as well as each of the value chain stages. Thus, managing risks and the uncertain availability of information will lead farmers to - take advantage of these managerial, technical and social based-solutions. This implies the need for innovative technology-based knowledge management system to capture the agricultural information, at a variety of regional locations, in terms of - collecting, storing, processing, and disseminating information about uncertain environmental conditions that affect agricultural decision-making production systems. Hence, from the genetic design of the seed, till their planting and harvest - processes, RUCAPS provides knowledge of the full agricultural life-cycle based-decision making process to realise the key impacts of every stage of the agriculture-related processes. Therefore, RUCAPS implies the development of a high impact research - project in order to integrate real-life based agriculture requirements, alternative land management scenarios, unexpected weather and environmental conditions as well as supporting innovation in the development of agriculture production systems, - operations, logistics and supply chain management and the impact of these systems and processes over the end-users and customers. This is to be conceived through the integration of standard and customised solutions for facilitating the collaborative - engagement within the agriculture value chain. - - 2020-10-02, ongoing project - - - 2016-10-03 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - United Kingdom - - - RUC-APS - - - H2020-MSCA-RISE-2015 - - - 691249 - - - - - UNIVERSITE DU LUXEMBOURG - UNIVERSITA DEGLI STUDI DI TORINO - ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA - THE UNIVERSITY OF HUDDERSFIELD - INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE - APIS HRISTOVICH EOOD - NOMOTIKA SRL - DLVSYSTEM SRL - - - EUR 1 152 000 - - - MIREL - MIning and REasoning with Legal texts - - - EUR 1 264 500 - - - Luxembourg - Italy - Italy - United Kingdom - France - Bulgaria - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Denise Ogden - Tel.: +44-1484-473192 - Fax: +44-1484-472682 - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The management of large repositories of norms, and the semantic access and reasoning to these norms are key challenges in Legal Informatics. The MIREL project will create an international and inter-sectorial network to define - a formal framework and to develop tools for MIning and REasoning with Legal texts, with the aim of translating these legal texts into formal representations that can be used for querying norms, compliance checking, and decision support. The - development of the MIREL framework and tools will be guided by the needs of three industrial partners, and validated by industrial case studies. MIREL promotes mobility and staff exchange between SMEs to academies in order to create an - inter-continental interdisciplinary consortium in Law and Artificial Intelligence areas including Natural Language Processing, Computational Ontologies, Argumentation, and Logic & Reasoning. - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Luxembourg - - - MIREL - - - H2020-MSCA-RISE-2015 - - - 690974 - - - - - UNIVERSITAT DE BARCELONA - - - EUR 158 121,60 - - - Unlocking the virtual body: Exploiting the symbiotic relationship between an avatar and its user to modify bodily experience and improve the outcome of eating disorder treatment - - - EUR 158 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - Successfully fighting eating disorders (EDs), whose prevalence is rising and expected to be one of the highest-ranking causes of mental illness in the Western world by 2020 with ever-increasing costs of institutional - healthcare in and beyond Europe, interdisciplinary efforts to elucidate their underlying, enigmatic, mechanism of body image disturbance, BID (the experience of one’s body as fatter/larger than it actually is) and improving the effectiveness of - existing evidence-based interventions are now imperative, also according to the European Council of EDs and the National Institute of Mental Health (USA). Substantial advances in this area crucially depend on improved understanding of disease - mechanisms while extant treatment strategies are hindered by the lack of specified conceptual models underlying the mechanism driving the extremes of BID in EDs, causing huge costs to individuals and society at large. However, as reported in the - top-tier journals, the applicant and co-workers’ “allocentric lock” model of EDs provides a rich conceptual framework for elucidating the source of BID and factors causing ED patients to be “locked” in a “virtual body” (e.g. my body is fat) that they - detest and differs from the real one. This interdisciplinary project (with integrated training), going beyond the state-of-the-art not only aims at a) providing further evidence for the existence of allocentric lock in EDs and b) assessing its neural - bases, but also c) setting and tuning a virtual reality-based embodiment device able to unblock the “virtual body” by exploiting the symbiotic relationship between an avatar and its user, and testing it in integrated first-line ED treatment - approaches (randomized controlled clinical trial). The Symbiotic Body project work, also having the potential to open a path to a new vision of e-health (strategic H-2020 area) -e-mbodied health, will be disseminated and notified to the international - scientific/clinical community and the general public. - - 2020-01-11, ongoing project - - - 2018-01-12 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - SYMBIOTIC BODY - - - H2020-MSCA-IF-2016 - - - 745948 - - - - - CENTRO DE INVESTIGACION COOPERATIVADE ENERGIAS ALTERNATIVAS FUNDACION - UNIVERSITE DE BORDEAUX - - - EUR 161 590,22 - - - Solid-state reactions for thermal energy storage - - - EUR 161 590,22 - - - Spain - France - - - Research Organisations - Higher or Secondary Education Establishments - - In this project proposal reversible solid-state chemical reactions (eutectoids, peritectoids) are proposed for the storing of thermal energy at high temperature (300-800 °C). The development of a novel heat storage concept, - based on solid-solid reactions, proposed in this project, could contribute to open new scenarios in the thermal energy storage field. To the best of our knowledge, the use of this class of reactions for TES applications has not been explored so far. - The goal of this study is the identification of solid-state reactions fulfilling a large number of scientific and technological requirements (high storage capacity, good thermal conductivity, mechanical and chemical stability, complete reversibility - of a charging/discharging cycles etc.). - - - 2019-03-14, ongoing project - - - 2017-03-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - Spain - - - SOLSTORE - - - H2020-MSCA-IF-2016 - - - 752520 - - - - - CENTRO DE INVESTIGACION ECOLOGICA YAPLICACIONES FORESTALES CONSORCIO - - - EUR 170 121,60 - - - Resilience of Soil Stoichiometry in subartic soils under Temperature-Induced Soil Carbon Losses: Where does the N go? - - - EUR 170 121,60 - - - Spain - - - Research Organisations - - Global warming can trigger enormous releases of carbon (C) from soils, with positive feedbacks to climate change. Northern high latitude soils can constitute a major contributor to this positive feedback loop. Climate change - predictions are however still largely uncertain, partly due the lack of accurate representation of vegetation and soil microbial feedbacks and C and nitrogen (N) interactions. Warming enhances microbial mineralization of soil organic matter (SOM) - (i.e. soil C outputs) to a higher degree than vegetation productivity (i.e. soil C inputs), resulting in large C losses from northern soils. Pioneer results point to proportional N losses in response to warming, which may be the key to this - phenomenon. This project will combine the expertise of a multidisciplinary group of leading researchers on ecosystem stoichiometry, stable N isotopic methods and applied biotechnology with the existence of unique and established research sites in - geothermal systems in Iceland to reveal the fate of N lost in response to warming, and uncover the mechanisms behind observed soil C losses. StoiCa will elucidate, for first time, three key knowledge gaps: (1) the rates, forms and mechanisms of N - losses from arctic soils under warming; (2) the transient- and persistent responses and the warming-induced transitions from a closed to a leaky, open N cycle; (3) the shifts towards a more symbiotic N cycle and role of thermo-adapted mycorrhiza in - stimulating plant growth. This proposal directly addresses two cross-cutting priorities of sustainable development and climate action from the H2020 Work Programme. It also represents an exceptional opportunity for the candidate to acquire the - essential skills that she lacks and that will convert her into a highly competitive European researcher in climate change biogeochemistry, while obtaining intersectorial capacities that will open new career avenues. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - StoiCa - - - H2020-MSCA-IF-2016 - - - 750252 - - - - - THE UNIVERSITY OF EXETER - - - EUR 183 454,80 - - - Perceptual Learning - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Perceptual learning is fundamental to human cognition. It can be defined as an enhancement in the ability to distinguish between similar stimuli (that otherwise would be very hard to tell apart) as a consequence of experience - with them, or with stimuli similar to the target stimuli. This allows the wine connoisseur to distinguish between different wines, the bird watcher to tell one warbler from another, and people to identify that face as a given person rather than - someone else, if the face is taken from an ethnic grouping that they are familiar with. My research focuses on the mechanisms responsible for perceptual learning. By using a range of neuroscience techniques (tDCS, fMRI, TMS/MEP, EEG/ERP) in - conjunction with the behavioural designs provided by experimental psychology I will investigate the neural basis for perceptual learning, test a computational model of the phenomenon, and try to control the development and expression of this - perceptual skill. This programme of research will train me in new techniques, further develop my expertise in the domain of perceptual learning, and allow me to work in one of the leading laboratories for this type of research at the present time. It - will also allow me to raise my and my discipline's profile, and to do this, as part of this research proposal, I will convene an International Workshop on Perceptual Learning to bring together the various researchers working on this issue and publish - the proceedings as an edited book. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - Perceptual Learning - - - H2020-MSCA-IF-2016 - - - 743702 - - - - - UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK - - - EUR 187 866 - - - Microbiota-immune interaction in colorectal cancer - - - EUR 187 866 - - - Ireland - - - Higher or Secondary Education Establishments - - The human gastrointestinal tract harbours trillions of bacteria that have co-evolved to play important roles in health and disease, conferring immunological, metabolic and neurological benefits to the host. This assemblage is - known as the Gut Microbiota and has been a focus of investigation over the last decade. Altered gut microbiota composition has been associated with colorectal cancer (CRC), and studies in germ-free mice established an important role for some gut - microbiota members in oncogenesis outcome, tumour progression and response to therapy. Data from the host laboratory show that patients with CRC harbour specific gut microbiota sub-types, among which some are associated with distinct mucosal - gene-expression profiles. Thus either directly or through their metabolites, these tumour-associated microbiota appear to differentially recruit and interact with host inflammatory cells, which we hypothesize may be involved in different outcomes of - carcinogenesis. The presence of particular immune cells is known to be prognostic of clinical outcome, because it often creates a tumour-promoting environment. Therefore, strategies aimed at manipulating the tumour-associated microbiota in CRC - represent a promising therapeutic approach for patients. IMMUNO-CRC’s goal is to elucidate the mechanisms by which certain bacterial sub-types associated with CRC may alter immune function and influence clinical outcome. Using multicolour flow - cytometry, I will analyse infiltrating immune cells characteristic of different inflammatory responses and microbiota sub-types. Histo-immunophenotyping analysis on tumour biopsies will determine their inflammation and cancer phenotype. Metabolomics - will identify specific microbial metabolites involved in the regulation and progression of inflammation. Ultimately, this unique and innovative combination of techniques will pave the way for novel therapeutics targeting the human microbiota for - cancer treatment. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Ireland - - - IMMUNO_CRC - - - H2020-MSCA-IF-2016 - - - 752047 - - - - - UNIVERSITAT DE VALENCIA - - - EUR 170 121,60 - - - Molecular glues for perovskite materials - - - EUR 170 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - This project aims at optimizing the interface between halide perovskites and different semiconductors through the use of self-assembled monolayers (SAMs). Such interface engineering will be applied to perovskite solar cells - where SAMs will play the role of “molecular glues” between the active perovskite layer and charge transport layers (n- and p-type metal oxides as well as organic semiconductors). Through the grafting and self-assembly of short bifunctional molecules, - PerovSAMs will ensure a smooth and close contact at the interfaces, favouring charge transfer in the cell, thus minimizing losses and enhancing the power conversion efficiency (PCE). Furthermore, this versatile methodology will also be applied to - perovskite nanocrystals (NCs). Surface functionalization of the NCs with SAMs will allow the formation of a perovskite shell with a different chemical composition creating core-shell quantum dots with superior photovoltaic properties, boosting the - incipient field of perovskite NC-based solar cells. - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - PerovSAMs - - - H2020-MSCA-IF-2016 - - - 747599 - - - - - UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK - - - EUR 187 866 - - - Molecular Characterisation of Anthropogenic Secondary Organic Aerosols. - - - EUR 187 866 - - - Ireland - - - Higher or Secondary Education Establishments - - Secondary organic aerosol (SOA) accounts for a large fraction of atmospheric aerosol mass and can have significant effects on atmospheric composition, human health, and climate. However, considerable uncertainty exists on the - chemical composition of SOA, as well as the sources and processes leading to its formation in the atmosphere. In this project state-of-the-art analytical techniques will be used to determine the molecular composition of secondary organic aerosols in - ambient urban air and the identity of the precursor volatile organic compounds (VOCs). These field measurements will provide detailed information on VOCs and particle composition that can be linked to specific pollution sources, such as vehicle - emissions and biomass burning. A detailed programme of simulation chamber experiments will also be conducted to investigate the formation of SOA from anthropogenic VOCs that most strongly influenced aerosol composition at the measurement site. The - simulation chamber experiments will generate novel information on the reaction pathways for anthropogenic SOA formation that can be incorporated into atmospheric models dealing with both air quality and climate. Overall, the unique information - obtained from this combined field and laboratory study is expected to contribute to a greatly improved understanding of the composition, sources and processes leading to organic aerosol formation in the atmosphere, and in turn, the impact of SOA on - human health and climate. During this project, the Fellow will receive high quality training through research that will significantly improve scientific knowledge and provide a strong platform for building an independent research career. A wide range - of complementary and transferable skills will also be developed to enhance future career prospects. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - Ireland - - - MOCHA - - - H2020-MSCA-IF-2016 - - - 751527 - - - - - UNIVERSITAT DE VALENCIA - - - EUR 158 121,60 - - - Single-Molecule Spintronics: a Coordination Chemistry Approach to Quantum Computing - - - EUR 158 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - The project proposed herein develops in the frame of the Coordination Chemistry approach to Molecular Magnetism and Molecular Spintronics, aiming at the design, synthesis and characterisation of new prototypes of - multifunctional and multiresponsive molecular magnetic devices based on Single Ion Magnets (SIMs), as models of electro- and photoswitchable multiple Quantum Bits and Quantum Gates (QGs) for the physical implementation of Quantum Information - Processing in the emerging field of Quantum Computation. - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - Spain - - - SIMOF - - - H2020-MSCA-IF-2016 - - - 748921 - - - - - UNIVERSITAT DE VALENCIA - - - EUR 159 126 - - - Molecule for low diffusion TPCs for rare event searches - - - EUR 159 126 - - - Spain - - - Higher or Secondary Education Establishments - - One of the most promising technologies to search for neutrinoless double beta decay (0nubb) is a high pressure xenon gas (HPGXe) time projection chamber (TPC) with electroluminescent (EL) amplification. The key advantage of an - EL HPGXe TPC is the capability to uniquely image the track of the two emitted electrons in a 0nubb event, together with high energy resolution. The current imaging performance is limited by the diffusion of the ionization electrons during drift. This - proposal describes a research program to reduce diffusion by adding CH4 molecular additives to the xenon gas to improve the imaging capability in an EL HPGXe TPC enhancing the sensitivity to the 0nubb decay, within the context of the NEXT - collaboration. Dr. Lopez March and the two supervisors Prof. Gomez Cadenas and Prof. Nygren propose to develop the project in two stages: 1) characterization of the CH4 molecular additive in a small detector at the University of Texas at Arlington - (UTA), Outgoing Phase); 2) exploit the new gas mixture to perform the measurement of the topological signature with the NEXT-DEMO TPC at the Instituto de Fisica Corpuscular (SPAIN) and with the NEW TPC at the underground Laboratorio Subterr\'aneo de - Canfranc (LSC) (Return Phase). The objectives of the MELODIC project have been planned to boost the career development of the fellow. The overall training received by Dr. Lopez March in the proposed research project will give her independence and - professional maturity. She will become a truly, multidisciplinary researcher capable of integrating different areas of research (operation of detectors and physics data analysis) making her uniquely trained for leading her own line of research. - - 2019-09-17, ongoing project - - - 2017-09-18 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Spain - - - MELODIC - - - H2020-MSCA-IF-2016 - - - 740055 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 149 921 - - - BOTFIND: Finding Bots, Detect Harassing Automation, and Restoring Trust in Social Media Civic Engagement - - - EUR 149 921 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Social media platforms have become tools for manipulating public opinion during elections. In particular, “bots” are algorithms that automate rapid, widespread interactions with citizens, often with deleterious effects on - public knowledge of science, social inequality, and public policy options. Through the ERC COMPROP Consolidator award, researchers have demonstrated that even simple bots (i) effectively keep negative messages and fake news in circulation longer (ii) - target journalists and civil society groups and (iii) operate with little oversight from social media firms. Such algorithms have negative consequences both for public trust in technology innovation and for the quality of public deliberation in - Europe’s democracies. ERC researchers have been able to identify highly automated, politically-manipulative social media accounts post hoc. This project will allow researchers to take what we have learned and produce an online tool that allows people - to evaluate suspicious social media accounts. Most social media platforms are slow to address troll and bot activity, so this innovative tool will put ERC research into public service in Europe—and around the world. - - 2019-01-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - BOTFIND - - - ERC-2017-PoC - - - 767454 - - - - - HELSINGIN YLIOPISTO - HELSINGIN YLIOPISTO - - - EUR 2 420 429 - - - Translational implications of the discovery of brain-draining lymphatics - - - EUR 2 420 429 - - - Finland - Finland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In 2010, 800 billion Euros was spent on brain diseases in Europe and the cost is expected to increase due to the aging population. – Here I propose to exploit our new discovery for research to alleviate this disease burden. In - work selected by Nature Medicine among the top 10 ”Notable Advances” and by Science as one of the 10 ”Breakthroughs of the year” 2015, we discovered a meningeal lymphatic vascular system that serves brain homeostasis. We want to reassess current - concepts about cerebrovascular dynamics, fluid drainage and cellular trafficking in physiological conditions, in Alzheimer’s disease mouse models and in human postmortem tissues. First, we will study the development and properties of meningeal - lymphatics and how they are sustained during aging. We then want to analyse the clearance of macromolecules and protein aggregates in Alzheimer’s disease in mice that lack the newly discovered meningeal lymphatic drainage system. We will study if - growth factor-mediated expansion of lymphatic vessels alleviates the parenchymal accumulation of neurotoxic amyloid beta and pathogenesis of Alzheimer’s disease and brain damage after traumatic brain injury. We will further analyse the role of - lymphangiogenic growth factors and lymphatic vessels in brain solute clearance, immune cell trafficking and in a mouse model of multiple sclerosis. The meningeal lymphatics could be involved in a number of neurodegenerative and neuroinflammatory - diseases of considerable human and socioeconomic burden. Several of our previous concepts have already been translated to clinical development and we aim to develop proof-of-principle therapeutic concepts in this project. I feel that we are just now - in a unique position to advance frontline European translational biomedical research in this suddenly emerging field, which has received great attention worldwide. - - 2022-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Finland - - - BrainDrain - - - ERC-2016-ADG - - - 743155 - - - - - UNIVERSITAT DE BARCELONA - UNIVERSITAT DE BARCELONA - - - EUR 1 835 220 - - - Beyond Precision Cosmology: dealing with Systematic Errors - - - EUR 1 835 220 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Over the past 20 years cosmology has made the transition to a precision science: the standard cosmological model has been established and its parameters are now measured with unprecedented precision. But precision is not - enough: accuracy is also crucial. Accuracy accounts for systematic errors which can be both on the observational and on the theory/modelling side (and everywhere in between). While there is a well-defined and developed framework for treating - statistical errors, there is no established approach for systematic errors. The next decade will see the era of large surveys; a large coordinated effort of the scientific community in the field is on-going to map the cosmos producing an - exponentially growing amount of data. This will shrink the statistical errors, making mitigation and control of systematics of the utmost importance. While there are isolated and targeted efforts to quantify systematic errors and propagate them - through all the way to the final results, there is no well-established, self-consistent methodology. To go beyond precision cosmology and reap the benefits of the forthcoming observational program, a systematic approach to systematics is needed. - Systematics should be interpreted in the most general sense as shifts between the recovered measured values and true values of physical quantities. I propose to develop a comprehensive approach to tackle systematic errors with the goal to uncover and - quantify otherwise unknown differences between the interpretation of a measurement and reality. This will require to fully develop, combine and systematize all approaches proposed so far (many pioneered by the PI), develop new ones to fill the gaps, - study and explore their interplay and finally test and validate the procedure. Beyond Precision Cosmology: Dealing with Systematic Errors (BePreSysE) will develop a framework to deal with systematics in forthcoming Cosmological surveys which, could, - in principle, be applied beyond Cosmology. - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Spain - - - BePreSysE - - - ERC-2016-COG - - - 725327 - - - - - FUNDACAO D. ANNA SOMMER CHAMPALIMAUD E DR. CARLOS MONTEZ CHAMPALIMAUD - FUNDACAO D. ANNA SOMMER CHAMPALIMAUD E DR. CARLOS MONTEZ CHAMPALIMAUD - - - EUR 150 000 - - - Neuroimmune activation as a novel therapeutic approach for IBD - - - EUR 150 000 - - - Portugal - Portugal - - - Research Organisations - Research Organisations - - NeurIMM has been designed to investigate the commercial and technical viability of a novel, targeted therapy for Inflammatory Bowel Disease (IBD), based on a recently uncovered signaling axis between intestinal type 3 innate - lymphoid cells (ILC3s) and enteric glial cells. This discovery by the team of Prof. Henrique Veiga-Fernandes in the ERC CoG grant 647274 ‘GliaInnateSensing’ was recently published in Nature (Ibiza et al, Nature 2016). NeurIMM proposes the use of a - glial cell-derived immunomodulator to restore intestinal homeostasis, by inducing a tissue protective immune response. Importantly, this novel therapy will also promote tissue healing to reverse immune-cell mediated tissue damage, leading to improved - outcomes for the patient. This could have major implications for patients suffering from IBD. In addition, this approach also has potential as an effective therapy against cancer, (pediatric) gastroenteritis and other inflammatory disorders. - - 2019-02-28, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Portugal - - - NeurIMM - - - ERC-2017-PoC - - - 764332 - - - - - ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA - ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA - - - EUR 1 997 000 - - - Alchemy in the Making: From ancient Babylonia via Graeco-Roman Egypt into the Byzantine, Syriac and Arabic traditions (1500 BCE - 1000 AD) - - - EUR 1 997 000 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The AlchemEast project is devoted to the study of alchemical theory and practice as it appeared and developed in distinct, albeit contiguous (both chronologically and geographically) areas: Graeco-Roman Egypt, Byzantium, and - the Near East, from Ancient Babylonian times to the early Islamic Period. This project combines innovative textual investigations with experimental replications of ancient alchemical procedures. It uses sets of historically and philologically - informed laboratory replications in order to reconstruct the actual practice of ancient alchemists, and it studies the texts and literary forms in which this practice was conceptualized and transmitted. It proposes new models for textual criticism in - order to capture the fluidity of the transmission of ancient alchemical writings. AlchemEast is designed to carry out a comparative investigation of cuneiform tablets as well as a vast corpus of Greek, Syriac and Arabic writings. It will overcome the - old, pejorative paradigm that dismissed ancient alchemy as a "pseudo-science", by proposing a new theoretical framework for comprehending the entirety of ancient alchemical practices and theories. Alongside established forms of scholarly output, such - as critical editions of key texts, AlchemEast will provide an integrative, longue durée perspective on the many different phases of ancient alchemy. It will thus offer a radically new vision of this discipline as a dynamic and diversified art that - developed across different technical and scholastic traditions. This new representation will allow us to connect ancient alchemy with medieval and early modern alchemy and thus fully reintegrate ancient alchemy in the history of pre-modern alchemy as - well as in the history of ancient science more broadly. - - 2022-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Italy - - - AlchemEast - - - ERC-2016-COG - - - 724914 - - - - - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - - - EUR 1 483 992 - - - Justice, Morality, and the State in Amazonia - - - EUR 1 483 992 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The project will investigate the social, cultural and cognitive bases of justice, or the morally correct assignment of goods and evils, with a focus on the indigenous peoples of Western Amazonia. It will develop an analysis of - issues ranging from emotions, fairness, entitlement and equality in contexts of resource distribution, to punishment, vengeance, and attributions of responsibility. This will enlarge our understanding of how and why patterns of moral judgement vary - across cultures, with particular attention paid to the role played by cultural constructions of personhood. The current situation of rapid social change in Amazonia, driven largely by the increased presence of the state in everyday life, provides a - unique opportunity for assessing how morality and ethics are shaped by social conditions such as the size of networks of cooperation, processes for generating consensus, and the management of conflicts and disputes. This will be used to address - longstanding questions concerning the evolution of morality, including how fairness is linked to cooperation within ever larger groups. The innovative methodology, combining ethnography with experiments and games adapted from psychology, economics, - and experimental philosophy, will allow for a vastly more comprehensive set of data on justice in action than has previously been achieved. This will permit the elaboration of a sophisticated and distinctively Amazonian theory of justice, grounded in - emotional responsiveness to others and respect for personal autonomy, that is capable of entering into critical dialogue with mainstream Western theories and understandings, while also challenging a number of dominant stereotypes of small-scale, - non-state societies. The results will further be used to formulate a general framework for development projects and policy interventions with indigenous peoples, which could drastically improve their success rate and potentially be adapted for use in - a range of global contexts. - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - JUSTAM - - - ERC-2016-STG - - - 715725 - - - - - UNIVERSITAT DE VALENCIA - UNIVERSITAT DE VALENCIA - - - EUR 1 969 821 - - - Collective Infectious Units and the Social Evolution of Viruses - - - EUR 1 969 821 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - A widely accepted view in virology is that virions function as independent infectious units. However, recent work by us and others indicates that viruses are often transmitted as more complex structures, such as virion - aggregates, lipid vesicles or protein matrices harbouring multiple infectious particles. This demonstrates that viruses can be transmitted as “collective infectious units”, in sharp contrast with the current paradigm. Critically, these recent - discoveries now set the stage for the evolution of social interactions, a previously unappreciated facet of viruses. I propose to investigate how collective infectious units drive virus social evolution using state-of-the-art tools from the fields of - virology, genetics, structural biology, and nanotechnology. The effects of collective infectivity on viral fitness will be tested directly using experimental evolution and genetic engineering, and confirmed in vivo. Three widely different viruses - will be used to achieve generality: human enteroviruses, a vector-borne rhabdovirus, and a baculovirus. Furthermore, the implications of virus social interactions for the maintenance of genetic diversity, evolvability, virulence evolution, and the - emergence of drug resistance will be investigated. Radically new processes such as the putative extracellular fusion of viral particles will be also explored. I expect that infectious units constituted by viruses from different species will be - uncovered as well, with far-reaching implications for epidemiology. It is becoming increasingly recognized that parasite sociality is a disease determinant, and our results may therefore inspire new antiviral strategies. In sum, this project aims at - laying the foundations of virus sociality from a mechanistically-informed, bottom-up approach. Importantly, beyond their practical importance viruses will also provide a simple and tractable system that will help us to establish more general - principles of social evolution. - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Spain - - - Vis-a-Vis - - - ERC-2016-COG - - - 724519 - - - - - UNIVERSITAT DE VALENCIA - UNIVERSITAT DE VALENCIA - - - EUR 1 998 750 - - - Smart Coordination Polymers with Compartmentalized Pockets for Adaptive Guest Entrance - - - EUR 1 998 750 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The S-CAGE project aims to develop a new generation of crystalline solids with periodically-organized discrete voids, or compartments, that would benefit from the combination of the high stability and robustness of dense - materials with the structural diversity and versatility (and therefore large applicability) of open frameworks. These coordination polymers (CPs) will be capable of interacting with guest species in the absence of large channels or permanent pores - due to the presence of dynamic entrances. This could open new horizons towards the design of unprecedented materials as an enhanced interplay between the guests and the frameworks will be achieved resulting from the confined space of the - compartmentalized pockets. - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Spain - - - S-CAGE - - - ERC-2016-COG - - - 724681 - - - - - SIMULA RESEARCH LABORATORY AS - SIMULA RESEARCH LABORATORY AS - - - EUR 1 500 000 - - - Mathematical and computational foundations for modeling cerebral fluid flow. - - - EUR 1 500 000 - - - Norway - Norway - - - Research Organisations - Research Organisations - - Your brain has its own waterscape: whether you are reading or sleeping, fluid flows through the brain tissue and clears waste in the process. These physiological processes are crucial for the well-being of the brain. In spite - of their importance we understand them but little. Mathematics and numerics could play a crucial role in gaining new insight. Indeed, medical doctors express an urgent need for multiscale modeling of water transport through the brain, to overcome - limitations in traditional techniques. Surprisingly little attention has been paid to the numerics of the brain's waterscape however, and fundamental knowledge is missing. - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Norway - - - Waterscales - - - ERC-2016-STG - - - 714892 - - - - - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - - - EUR 1 497 505 - - - The Design of Social Policy in a Heterogeneous World - - - EUR 1 497 505 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Modern societies are characterized by tremendous heterogeneity in economic outcomes: from heterogeneity in wages and employment, to heterogeneity in capital income, wealth and health outcomes. It is unclear, however, how to - map heterogeneity in these outcomes to heterogeneity in welfare. This mapping is crucial for the design of tax and benefit systems, providing insurance against individual risk and redistributing income between individuals, while maintaining proper - incentives. - - 2022-01-31, ongoing project - - - 2017-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - HETEROPOLIS - - - ERC-2016-STG - - - 716485 - - - - - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - - - EUR 1 489 518 - - - Addressing Too Big to Fail: Resolution, Organizational Structure, and Funding of Global Banks - - - EUR 1 489 518 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - One of the main unresolved challenges of the recent financial crisis is how society should deal with global banks that are “too big to fail.” The collapse of Lehman Brothers vividly demonstrated the costs of the failure of - such an institution, with sweeping repercussions for the financial system and the broader economy. Yet, implicit public guarantees that would prevent such failures are equally costly, creating moral hazard in the form of increased risk taking and - incentives for financial institutions to become larger and more complex. - - 2021-11-30, ongoing project - - - 2016-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - TBTF - - - ERC-2016-STG - - - 715467 - - - - - CARDIFF AND VALE UNIVERSITY HEALTH BOARD - UNIVERSITAT DE BARCELONA - HOSPITAL CLINIC I PROVINCIAL DE BARCELONA - CARDIFF UNIVERSITY - - - EUR 274 500 - - - International impact of TALK©: a simple and practical approach to multi-professional structured feedback and debriefing, to be used after unplanned learning events in clinical environments. - - - EUR 274 500 - - - United Kingdom - Spain - Spain - United Kingdom - - - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - TALK© is a communication tool which aims to guide multi-professional clinical teams learning and improving quality of patient care and patient safety together. It is a simple and practical approach to multi-professional - structured feedback and debriefing, to be used after unplanned learning events in clinical environments. - - - 2020-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - United Kingdom - - - TALK - - - H2020-MSCA-RISE-2016 - - - 734753 - - - - - UNIVERSITAT DE BARCELONA - UNIVERSITAT DE BARCELONA - - - EUR 149 962 - - - Making Complex Gas Analytics Friendly and Available ASAP - - - EUR 149 962,50 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - GasApp aims at bringing the capability to detect gases to every existing smartphone in just a few months. Carrying out a gas measurement will be as simple as taking a snapshot with the phone’s camera. Technically, we will rely - on colorimetry methods to turn the presence of chemical substances into colour changes. GasApp wants to take a fast track towards accurate, highly specific, and highly accessible measurements by rethinking the concept of “ubiquitous sensing”. Instead - of developing new complex electronic devices, our approach builds upon existing ubiquitous devices (i.e. smartphones), a new software App and inexpensive Tags based on knowledge produced in an ERC-funded project to achieve a user friendly gas-sensing - product ASAP, and making business out of this opportunity. - - - 2018-06-30, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Spain - - - GasApp - - - ERC-2016-PoC - - - 727297 - - - - - KING'S COLLEGE LONDON - KING'S COLLEGE LONDON - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 499 095 - - - Authority and Innovation in Early Franciscan Thought (c. 1220-56) - - - EUR 1 499 095 - - - United Kingdom - United Kingdom - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - INNOVATION anticipates a breakthrough in scholarly understanding of the medieval origins of modern Western philosophy. This breakthrough will be achieved by exposing the pioneering nature of early thirteenth-century Franciscan - thought and its pivotal significance for the subsequent formation of the Western philosophical identity. The work of early Franciscans has largely been neglected in scholarly circles, on the assumption that they merely codified the work of past - authorities, where later Franciscans developed innovative ideas that laid the foundation for the development of modern philosophy. INNOVATION will contest this assumption by producing the first comprehensive study of the sources, method, content, and - later medieval reception of early Franciscan thought. In conducting this study, I will implement a groundbreaking method of reading scholastic texts, which is attentive to the way that practice informed theory in the high Middle Ages. This - ‘practice-led’ hermeneutic will provide a resource for re-envisaging the entire state of the art in the study of scholasticism. As regards early Franciscans, it will allow me to identify novelty, often due to the use of Islamic sources, where past - scholars have perceived unoriginality. On this basis, I will highlight previously unnoticed connections between the early and late Franciscan schools. By these means, I will illustrate how Western thought has been nourished by the ethos of a - particular religious order and by Islamic thought, pointing up a shared Muslim-Western philosophical identity that is often overlooked but urgently needed to overcome severe fractures in today’s society. At the same time, I will emphasize that - Franciscan ideas only became modern once removed from their practice-led context. In juxtaposing the cultural paradigms of philosophy and religious practice, consequently, I will advance knowledge by producing the first nuanced scholarly account of - the Franciscan origins of modern Western thought. - - 2021-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - INNOVATION - - - ERC-2016-STG - - - 714427 - - - - - CONSIGLIO NAZIONALE DELLE RICERCHE - STAZIONE ZOOLOGICA ANTON DOHRN - UNIVERSITETET I TROMSOE - THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN - HELMHOLTZ ZENTRUM FUR OZEANFORSCHUNG KIEL - KATHOLIEKE UNIVERSITEIT LEUVEN - UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK - ECOAST - FUNDACION CENTRO DE EXCELENCIA EN INVESTIGACION DE MEDICAMENTOS INNOVADORES EN ANDALUCIA - MICRODISH BV - CONSORZIO ITALBIOTEC - - - EUR 2 853 005,40 - - - Improving the flow in the pipeline of the next generation of marine biodiscovery scientists - - - EUR 2 853 005,40 - - - Italy - Italy - Norway - United Kingdom - Germany - Belgium - Ireland - Belgium - Spain - Netherlands - Italy - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - - MarPipe is a consortium of 11 partners (IBP-CNR, SZN, UiT, UNIABDN, GEOMAR, KULeuven, UCC, eCOAST, MEDINA, MicroDish, Italbiotec) based in 8 countries (I, N, UK, D, B, IRL, E, NL), including 3 from the non-academic sector. We - will train 11 ESRs in marine drug-discovery, providing these researchers with unique skills toward becoming world leaders in this research field and to advance their careers in academia or industry. MarPipe PhDs will be trained in a programme - including training-by-research, joint courses of technical, scientific and transferrable skills, active participation to public scientific events, and an intense inter-sectoral networking exchange plan. - - - 2020-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Italy - - - MarPipe - - - H2020-MSCA-ITN-2016 - - - 721421 - - - - - UNIVERSITAT DE VALENCIA - UNIVERSITAT DE VALENCIA - - - EUR 1 527 351,26 - - - Chemical Engineering of Functional Stable Metal-Organic Frameworks: Porous Crystals and Thin Film Devices - - - EUR 1 527 351,26 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Metal-Organic-Frameworks (MOFs) offer appealing advantages over classical solids from combination of high surface areas with the crystallinity of inorganic materials and the synthetic versatility (unlimited combination of - metals and linkers for fine tuning of properties) and processability of organic materials. Provided chemical stability, I expect combination of porosity with manipulable electrical and optical properties to open a new world of possibilities, with - MOFs playing an emerging role in fields of key environmental value like photovoltaics, photocatalysis or electrocatalysis. The conventional insulating character of MOFs and their poor chemical stability (only a minimum fraction are hydrolytically - stable) are arguably the two key limitations hindering further development in this context. - - 2021-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Spain - - - chem-fs-MOF - - - ERC-2016-STG - - - 714122 - - - - - UNIVERSITAT DE BARCELONA - - - EUR 158 121,60 - - - Understanding the role of environmental and climatic changes in shaping subterranean diversity to preserve Europe’s unique hidden biodiversity - - - EUR 158 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - Climate warming and other anthropogenic perturbations are affecting ecosystems worldwide, contributing to the sixth mass extinction. Documenting and explaining a vanishing biodiversity are major challenges in evolutionary and - ecological research, but understanding biodiversity is an essential step towards halting its loss and the degradation of ecosystem services, a headline target of EU 2020 biodiversity strategy. Caves are isolated and extreme habitats that, like - oceanic islands, offer unparalleled opportunities for biodiversity research. Subterranean ecosystems are simpler than surface ones. Their stable climatic conditions, scarcity of food and absence of light drive the evolution of highly adapted fauna. - Because of the difficulty to access and explore caves and the rarity of cave dwelling organisms, the study of the subterranean realm has lagged behind the research conducted in other experimental ecosystems. Despite of their reputedly stable climatic - conditions, recent studies show that global warming may impact subterranean habitats by rising temperatures and, consequently, threatening troglobionts, which have low tolerance to temperature variations, causing the reduction of optimal habitat and - driving narrowly distributed species to extinction. HIDDENLIFE project aims to improve our understanding of one of the top biodiversity hotspots in Europe–the Dinarides, and its unique cave fauna, to ensure its conservation and future well-being. - Through a multidisciplinary approach that combines state of the art molecular and statistical tools, I will investigate the systematics, phylogeography, and environmental preferences of three independent lineages of cave spiders. This will contribute - to untangling the mechanisms that shaped their origin and present day diversity and distribution. By projecting potential distributions under predicted scenarios of global warming, I will predict future habitat suitability and assess vulnerability of - this unique and fragile fauna. - - 2019-06-04, ongoing project - - - 2017-06-05 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - HiddenLife - - - H2020-MSCA-IF-2016 - - - 749867 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - OROBOROS INSTRUMENTS GmbH - UNIVERSITAT DE VALENCIA - UNIVERSITA' DEGLI STUDI DI SIENA - THE QUEEN'S UNIVERSITY OF BELFAST - - - EUR 2 877 076,80 - - - Training in Cancer Mechanisms and Therapeutics - - - EUR 2 877 076,80 - - - Ireland - Austria - Spain - Italy - United Kingdom - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The European community requires early stage researchers (ESRs) trained in next-generation technologies for improved detection and treatment of oral and oesophageal cancers. The number of oral cancers diagnosed in the EU has - increased by over 75% in the last 30 years, with long-term survival rates of only 50%. This is typically due to the late diagnosis of the disease and resistance to current therapies. Through the collaborative expertise of clinicians, biochemists, - immunologists, and chemists TRACT will enable ESRs to discover novel insights into the molecular and cellular basis of these cancers and generate new diagnostic tools and therapeutics that improve patient response and survival. Each Institution - brings unique but complementary expertise in cancer metabolism, metabolomics, high-resolution imaging, biomarker identification, computational modelling, medicinal chemistry, target validation, drug development and translational medicine. Industrial - placements in five European countries will ensure ESRs receive specialised training in the development of next-generation technologies in such areas as whole genome sequencing, CRISPR technology, drug screening, exosome isolation and analysis, cancer - imaging, metabolism and metabolite analysis in addition to the unique employment experience of working in the private sector. Courses in commercialisation, project management and presentation skills will ensure ESRs will have the ability to present - their results to the entire cross-section of the European community, through public engagement. TRACT will deliver a cohort of internationally mobile cancer researchers with interdisciplinary skills who will have enhanced career prospects and be in a - position to have an impact on the European and global research stage by providing new technologies that can drive entrepreneurship into the European economy and improved diagnostics and treatment options for cancer patients in Europe and beyond. - - 2020-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Ireland - - - TRACT - - - H2020-MSCA-ITN-2016 - - - 721906 - - - - - DUNDALK INSTITUTE OF TECHNOLOGY - Institut Català de Recerca de l'Aigua, Fundació Privada - EESTI MAAULIKOOL - FORSCHUNGSVERBUND BERLIN EV - KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW - UNIVERSITAT DE BARCELONA - UNIVERSITE DE GENEVE - UPPSALA UNIVERSITET - - - EUR 3 056 654,16 - - - Management of Climatic Extreme Events in Lakes Reservoirs for the Protection of Ecosystem Services - - - EUR 3 056 654,16 - - - Ireland - Spain - Estonia - Germany - Netherlands - Spain - Switzerland - Sweden - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Environmental perturbations to lakes and reservoirs occur largely as episodic climatic events. These range from relatively short mixing events to storms and heat waves. While the driving events occur along a continuum of - frequency and magnitude, however, their effect is generally longer lasting than the events themselves. In addition, the more extreme weather events are now becoming increasingly frequent, a trend that has been linked to directional climate change and - is projected to continue in the coming decades. Understanding the impact of these short-lived pressures requires monitoring that captures the event (hours–days) and the ensuing impact, that can last for months or even years. Only recently has - automated high frequency monitoring (HFM) of lakes been adopted throughout Europe. This Training Network will investigate the effects of the most extreme events, and of cumulative lower magnitude events, using HFM, while at the same time training a - cohort of doctoral students in state-of-the art technology, data analysis and modelling. The aim of the EJD is to change the way in which water quality monitoring is carried out so that the effects of episodic climatic events can be understood, thus - ensuring that future water management strategies can explicitly account for their effects. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-EJD - European Joint Doctorates - - - Ireland - - - MANTEL - - - H2020-MSCA-ITN-2016 - - - 722518 - - - - - UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK - UNIVERSITY OF STRATHCLYDE - INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER - WAVEC/OFFSHORE RENEWABLES - CENTRO DE ENERGIA OFFSHORE ASSOCIACAO - CONSORCIO PARA EL DISENO, CONSTRUCCION, EQUIPAMIENTO Y EXPLOTACION DE LA PLATAFORMA OCEANICA DE CANARIAS - SINTEF ENERGI AS - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - CONSIGLIO NAZIONALE DELLE RICERCHE - UNIVERSITEIT GENT - STICHTING MARITIEM RESEARCH INSTITUUT NEDERLAND - UPPSALA UNIVERSITET - AALBORG UNIVERSITET - BIRD & BIRD LLP - - - EUR 1 999 798,75 - - - Marine Renewable Energy Research Infrastructure - - - EUR 1 999 798,75 - - - Ireland - United Kingdom - France - Portugal - Spain - Norway - Germany - Italy - Belgium - Netherlands - Sweden - Denmark - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The objective of MARINERG-i is to become the leading internationally distributed infrastructure in the Marine Renewable Energy (MRE) sector. Its integrated nature and co-ordinated approach will accelerate the research - development and deployment of offshore wind, wave, tidal and combined energy technologies and help maintain Europe as a global leader in this industry. In addition MARINERG-i will strengthen European, scientific and engineering excellence and - expertise as it’s combined facilities represent an indispensable tool to foster innovation across a large variety of MRE technologies and systems and through all key stages of technology development (TRL’s 1-9). - - - 2019-06-30, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-02-2016 - Preparatory Phase and support to early phase of ESFRI projects - - - RIA - Research and Innovation action - - - Ireland - - - MARINERGI - - - H2020-INFRADEV-2016-2 - - - 739550 - - - - - THE UNIVERSITY OF EDINBURGH - THE UNIVERSITY OF EDINBURGH - - - EUR 2 456 120 - - - f-block hydrocarbon interactions: exploration; exploitation - - - EUR 2 456 120 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Understanding, controlling, and predicting the subtle interactions that hydrocarbons form with metals is a major challenge in molecular science, and a key technology enabler in areas such as homogeneous catalysis, drug - recognition, polymer properties, and metal recovery. For the f-block, it is important due to the urgent need for clean access to critical elements such as neodymium, and the safe handling of nuclear waste. However, technical challenges of - paramagnetism, radiotoxicity, and relativistic effects, make quantifying and exploiting f-block hydrocarbon interactions very hard using traditional methods or calculations alone. - - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - f-ex - - - ERC-2016-ADG - - - 740311 - - - - - ARISTOTELIO PANEPISTIMIO THESSALONIKIS - ECOLE NATIONALE SUPERIEURE DES MINES DE PARIS - FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG - UNIVERSITAET FUER BODENKULTUR WIEN - POLITECNICO DI TORINO - UPPSALA UNIVERSITET - ASTON UNIVERSITY - ADVANCED TECHNOLOGY PARTNERS SRL - THE UNIVERSITY OF SHEFFIELD - OSSDSIGN AB - ESTIA CONSULTING & ENGINEERING S.A. - BEIJING UNIVERSITY OF CIVIL ENGINEERING AND ARCHITECTURE - FEDERAL STATE BUDGETARY EDUCATIONAL INSTITUTION OF HIGHER EDUCATION NOSOV MAGNITOGORSK STATE TECHNICAL UNIVERSITY - Shanghai University - FEDERAL STATE-FUNDED EDUCATION INSTITUTION OF HIGHER PROFESSIONAL EDUCATION PERM NATIONAL RESEARCH POLYTECHNIC UNIVERSITY - Arizona Board of Regents - Michigan Technological University - SAINT PETERSBURG NATIONAL RESEARCH UNIVERSITY OF INFORMATION TECHNOLOGIES, MECHANICS AND OPTICS - University of Florida - - - EUR 900 000 - - - Fracture Across Scales and Materials, Processes and Disciplines - - - EUR 1 125 000 - - - Greece - France - Germany - Austria - Italy - Sweden - United Kingdom - Italy - United Kingdom - Sweden - Greece - China - Russia - China - Russia - United States - United States - Russia - United States - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Fracture of materials is problematic across many disciplines and scales, from large building collapses and costly preventative engineering fixes to the personal injuries caused by bone fracture. 80–90% of all structural - failures occur as a result of fatigue and thus fracture mechanisms. Extensive testing of materials for fracture parameters before use in specific applications can be costly, wasteful and prohibitive when creating large structures. Computer models can - be used to assess the probability and impact of fracture for a specific application and material, thus serving as a prediction tool. However, the models used are not accurate and reliable across multiple scales and across varying applications. - - - 2021-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Greece - - - FRAMED - - - H2020-MSCA-RISE-2016 - - - 734485 - - - - - KOBENHAVNS UNIVERSITET - IFOM FONDAZIONE ISTITUTO FIRC DI ONCOLOGIA MOLECOLARE - PANEPISTIMIO PATRON - KAROLINSKA INSTITUTET - KRAEFTENS BEKAEMPELSE - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - UNIVERSITE DE GENEVE - STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS - ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON - KANCERA AB - - - EUR 3 990 269,16 - - - Targeting SYNthetic lethal interactions for new cancer treatments TRAINing network - - - EUR 3 990 269,16 - - - Denmark - Italy - Greece - Sweden - Denmark - United Kingdom - Switzerland - Netherlands - Greece - Sweden - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Breast and ovarian cancer constitute serious health challenges in the EU. To identify new improved cancer therapeutic approaches, we will pursue a multi-facetted synthetic lethal approach, which takes advantage of the inherent - genetic instability of cancer cells. Most mutations acquired by cancer cells do not cause lethality, but the very same mutations may cause cell death when a second gene in a redundant pathway is inactivated. Thus, targeting a gene that is synthetic - lethal together with a cancer-specific mutation will kill only cancer cells while sparing normal cells. Synthetic lethal approaches have been clinically pioneered by members of our consortium, by combining cancer-promoting mutations (e.g. in BRCA2) - with inactivating combinations of DNA repair genes. We will use this approach as the scientific frame for our ETN (SYNTRAIN) consisting of 9 academic and 1 SME beneficiary as well as 3 partners. We aim to identify synthetic lethal interactions and - exploit them to innovate future breast and ovarian cancer treatments through compound screening and development. SYNTRAIN consists of World leading researchers with complementary knowledge in genome maintenance and stress response pathways, and a - critical mass of expertise for providing an excellent training in screening methodologies, mechanistic investigations, and drug discovery. We will offer a structured training program that exceeds the capacities of each individual member. We will - educate a future generation of cancer researchers with a high innovative capacity and skills that enhances their career prospects in both academia and industry. Our aims are to train young researchers: i) in techniques preparing for a career in - cancer research, ii) in complementary skills relevant for work in academia and the pharma industry and iii) to become creative and entrepreneurial, capable of bridging the gap between basic and applied research. - - 2020-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Denmark - - - SYNTRAIN - - - H2020-MSCA-ITN-2016 - - - 722729 - - - - - KATHOLIEKE UNIVERSITEIT LEUVEN - - - EUR 160 800 - - - Probing local ROS distributions in Calcium signaling microdomains after myocardial infarction - - - EUR 160 800 - - - Belgium - - - Higher or Secondary Education Establishments - - An increasing number of people suffer cardiovascular diseases and experience myocardial infarction (MI). The subsequent heart remodeling is characterized by weaker contractility, hypertrophy and lethal arrhythmias. The - poorly-understood underlying mechanism is related to calcium (Ca2+) mishandling in cardiomyocytes and oxidative stress. To date, most of the studies described global cellular processes and were unable to propose efficient therapies. - - - 2019-07-17, ongoing project - - - 2017-07-18 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Belgium - - - MICROS - - - H2020-MSCA-IF-2016 - - - 752824 - - - - - LUNDS UNIVERSITET - LUNDS UNIVERSITET - - - EUR 1 990 895 - - - Collider Phenomenology and Event Generators - - - EUR 1 990 895 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Collider physics is about exploring the smallest constituents of matter, and unravelling the basic laws of the Universe. Unfortunately there can be a huge gap between a one-line formula of a fundamental theory and the - experimental reality it implies. Phenomenology is intended to fill that gap, e.g. to explore the consequences of a theory such that it can be directly compared with data. - - - 2020-10-31, ongoing project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Sweden - - - MorePheno - - - ERC-2014-ADG - - - 668679 - - - - - STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG - UNIVERSITAT DE VALENCIA - ISTITUTO NAZIONALE DI FISICA NUCLEARE - "NATIONAL CENTER FOR SCIENTIFIC RESEARCH ""DEMOKRITOS""" - - - EUR 3 795 000 - - - Astroparticle and Oscillations Research with Cosmics in the Abyss (ARCA and ORCA) - - - EUR 3 795 000 - - - Netherlands - France - Germany - Spain - Italy - Greece - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - - KM3NeT is a large Research Infrastructure that will consist of a network of deep-sea neutrino telescopes in the Mediterranean Sea with user ports for earth and sea sciences. The main science objectives, a description of the - technology and a summary of the costs are presented in the KM3NeT 2.0 Letter of Intent. Following the appearance of KM3NeT 2.0 on the ESFRI roadmap 2016 and in line with the recommendations of the Assessment Expert Group in 2013, this proposal - addresses the Coordination and Support Actions (CSA) to prepare a legal entity for KM3NeT, thereby providing a sustainable solution for the operation of the Research Infrastructure during ten (or more) years. During the EU-funded Design Study (2006 - - 2010) and Preparatory Phase (2008-2012), a cost-effective technology was developed, deep-sea sites were selected and the Collaboration was formed. This proposal constitutes a second Preparatory Phase. The project will be carried out within the - context of the current KM3NeT Collaboration which already has a provisional implementation of the management and governance of the Research Infrastructure in place. The resources requested will be complemented by the Collaboration. - - 2019-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-02-2016 - Preparatory Phase and support to early phase of ESFRI projects - - - CSA - Coordination and support action - - - Netherlands - - - KM3NeT 2.0 - - - H2020-INFRADEV-2016-2 - - - 739560 - - - - - CONSIGLIO NAZIONALE DELLE RICERCHE - UNIVERSITE PARIS DESCARTES - STIFTUNG FRANKFURT INSTITUTE FOR ADVANCED STUDIES - TECHNISCHE UNIVERSITAT DARMSTADT - - - EUR 3 481 874,75 - - - Goal-based Open-ended Autonomous Learning Robots - - - EUR 3 481 875 - - - Italy - France - Germany - Germany - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project aims to develop a new paradigm to build open-ended learning robots called `Goal-based Open-ended Autonomous Learning' (GOAL). GOAL rests upon two key insights. First, to exhibit an autonomous open-ended learning - process, robots should be able to self-generate goals, and hence tasks to practice. Second, new learning algorithms can leverage self-generated goals to dramatically accelerate skill learning. The new paradigm will allow robots to acquire a large - repertoire of flexible skills in conditions unforeseeable at design time with little human intervention, and then to exploit these skills to efficiently solve new user-defined tasks with no/little additional learning. This innovation will be - essential in the design of future service robots addressing pressing societal needs. The project will develop the GOAL paradigm by pursuing three main objectives: (1) advance our understanding of how goals are formed and underlie skill learning in - children; (2) develop innovative computational architectures and algorithms supporting (2a) the self-generation of useful goals based on user/task independent mechanisms such as intrinsic motivations, and (2b) the use of such goals to efficiently and - autonomously build large repertoires of skills; (3) demonstrate the potential of GOAL with a series of increasingly challenging demonstrators in which robots will autonomously develop complex skills and use them to solve difficult challenges in - real-life scenarios. The interdisciplinary project consortium is formed by leading international roboticists, computational modelers, and developmental psychologists working with complementary approaches. This will allow the project to greatly - advance our understanding of the fundamental principles of open-ended learning and to produce a breakthrough in the field of autonomous robotics by producing for the first time robots that can autonomously accumulate complex skills and knowledge in a - truly open-ended way. - - 2020-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-1-2014 - FET-Open research projects - - - RIA - Research and Innovation action - - - Italy - - - GOAL-Robots - - - H2020-FETOPEN-2014-2015-RIA - - - 713010 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 195 454,80 - - - ONCOWORM: Using functional genomics in highly regenerative flatworms to find novel cancer genes - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - This project will take direct action in exploiting the powerful planarian model system to achieve novel insights into the molecular processes underpinning oncogenesis and cancer. Based on the principle that biochemical and - physiological functions of many genes are conserved across phyla we will identify planarian genes that control the migration, proliferation and differentiation of the highly proliferative pluripotent adult stem cells (pASCs). We will combine a - bespoke specially designed partial irradiation assay, bioinformatic and expression based candidate gene identification and the capacity to perform RNAi based screens of gene function to identify novel genes controlling pASCs that are conserved in - humans. Those novel genes of greatest promise will then be studied in mammalian cancer cell lines using the insight gleaned from planarians. This project brings together, for the first time, a world-class planarian laboratory with an eminent cancer - cell biologist, Dr Kosaka, who will acquire all the expertise required to exploit the planarian system and at the same time transfer his extensive knowledge of cancer biology to the Aboobaker laboratory. - - 2018-04-04, Grant Agreement terminated - - - 2016-04-05 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - Oncoworm - - - H2020-MSCA-IF-2014 - - - 656816 - - - - - POLITECNICO DI TORINO - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - TEL AVIV UNIVERSITY - UNIWERSYTET WARSZAWSKI - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - ENVISENS TECHNOLOGIES SRL - PENTALUM TECHNOLOGIES LTD - SITAEL SPA - - - EUR 3 555 982,80 - - - Cloud-MicroPhysics-Turbulence-Telemetry: An inter-multidisciplinary training network for enhancing the understanding and modeling of atmospheric clouds - - - EUR 3 555 982,80 - - - Italy - United Kingdom - Germany - Israel - Poland - France - Italy - Israel - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Clouds are the largest source of uncertainty in weather prediction, climate science, and remain a weak link in modeling atmospheric circulation. This is rooted in the fact that clouds depend on the physical and chemical - processes over a huge range of scales, from the collisions of micron-sized droplets and particles to the airflow dynamics on the scales of thousands of meters. Since ambiguities related to representation of clouds in climate models prevail, - explorative observations are still needed. The challenge is on the one hand to establish connections across this range of scales, from aerosol and particle microphysics to macro-scale turbulent dynamics in clouds, and on the other to combine - knowledge and training across vastly different scientific and engineering disciplines. The aim of COMPLETE is to develop an inter/multidisciplinary training network that will prepare high-potential early stage researchers (ESRs) with both scientific - and industrially-oriented skills that will advance our understanding in these multi-scale complex natural phenomena. COMPLETE will vastly improve Europe’s position as a global leader in technology, science and innovation to address climate change - challenges. The training programme will combine the scientific investigation of specific aspects of cloud physics and related turbulent dynamics with training in key professional skills. This comprises an exceptional experimental programme that - includes field experiments, laboratory and numerical simulations, the design and development of advanced fast temperature probes, velocity MEMS and innovative atmospheric mini radio-sondes; all aimed at the production of new, Lagrangian based, cloud - fluctuation datasets, required to reduce the fragmentation of results and knowledge in this field. - - 2020-05-31, ongoing project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Italy - - - COMPLETE - - - H2020-MSCA-ITN-2015 - - - 675675 - - - - - THE UNIVERSITY OF BIRMINGHAM - KORE TECHNOLOGY LTD - IONICON ANALYTIK GMBH - UNIVERZITA KOMENSKEHO V BRATISLAVE - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSITATSMEDIZIN ROSTOCK - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - UNIVERSITAET INNSBRUCK - STICHTING KATHOLIEKE UNIVERSITEIT - USTAV FYZIKALNI CHEMIE J. HEYROVSKEHO AV CR, v. v. i. - - - EUR 2 538 628,20 - - - Ion-Molecule Processes for Analytical Chemical Technologies - - - EUR 2 538 628,20 - - - United Kingdom - United Kingdom - Austria - Slovakia - France - Germany - Germany - Austria - Netherlands - Czech Republic - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - Soft chemical-ionization mass-spectrometry (SCIMS) is an exquisitely sensitive analytical technique with applications to health, the environment and security that are vital to the EU. However, the recent, rapid and widespread - adoption of this technique has caught Europe unprepared. The resultant shortage in analytical chemical expertise has created an urgent need for highly skilled young researchers to be trained in the wide variety of SCIMS methods. IMPACT addresses this - skills’ shortage by establishing an intersectoral and multidisciplinary SCIMS training network. IMPACT also brings cohesion to the fragmented SCIMS research and development activities within the EU. To date, most SCIMS developments have been driven - not by users but by manufacturers, whose main focus has been on increased sensitivity. However, just as crucial is improved selectivity. Indeed, many users consider improved selectivity to be the key to taking SCIMS technology to a whole new level. - Instead of private and public sectors working independently, we need a fresh, intersectoral approach. IMPACT will achieve this through intersectoral work packages and multidisciplinary research projects. In place of major and costly changes in - instrumental design, IMPACT’s projects will focus on developing new methods for improved chemical specificity by manipulating ion chemistry. Hence, IMPACT’s fresh approach will produce a step change in SCIMS instrumentation to deliver both economic - and societal benefit to the EU. Specifically, IMPACT will train 10 ESRs within an integrated partnership of commercial, governmental and academic organisations, with planned secondments, 5 Advanced Training Courses, 7 interactive Complementary Skills - Workshops, and 4 ESR Centred Research Meetings. IMPACT will therefore provide Europe with both a world-class capability in SCIMS technology and a cohort of highly trained researchers who will bring the benefits of that technology to citizens across - the EU. - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - IMPACT - - - H2020-MSCA-ITN-2015 - - - 674911 - - - - - ACADEMISCH ZIEKENHUIS LEIDEN - LUDGER LTD - GENOS DOO ZA VJESTACENJE I ANALIZU - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - STICHTING VU - ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA - FACULDADE DE CIENCIAS MEDICAS DA UNIVERSIDADE NOVA DE LISBOA - NOVA ID FCT - ASSOCIACAO PARA A INOVACAO E DESENVOLVIMENTO DA FCT - STICHTING VUMC - - - EUR 3 293 890,66 - - - Exploiting Glycosylation of Colorectal Cancer for the development of improved diagnostics and therapeutics - - - EUR 3 293 890,66 - - - Netherlands - United Kingdom - Croatia - Germany - France - Netherlands - Italy - Portugal - Portugal - Netherlands - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - - Colorectal cancer (CRC) is a major worldwide cancer burden with about 1.4 million cases in 2012 and an annual mortality of approximately 700,000. Early detection is crucial as treatment is most efficient in early stages where - population based screenings could substantially reduce incidence and mortality. - - 2019-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Netherlands - - - GlyCoCan - - - H2020-MSCA-ITN-2015 - - - 676421 - - - - - UNIVERSITAT POLITECNICA DE CATALUNYA - GEORG-AUGUST-UNIVERSITAT GOTTINGENSTIFTUNG OFFENTLICHEN RECHTS - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS - INSTITUTO DE MICROCIRUGIA OCULAR DOS SLP - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIWERSYTET MIKOLAJA KOPERNIKA W TORUNIU - UNIVERSITY OF GLASGOW - PICOQUANT INNOVATIONS GMBH - - - EUR 3 495 300,48 - - - Advanced BiomEdical OPTICAL Imaging and Data Analysis - - - EUR 3 495 300,48 - - - Spain - Germany - Germany - United Kingdom - Spain - France - Poland - United Kingdom - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Biomedical imaging is a research field that is producing ground breaking scientific discoveries that enhance the health and life quality of European citizens and have a huge economic impact. In order to maintain Europe’s - leading position in the field, it is crucial to invest in the people who will lead R&D, and to promote the academic-private sector partnerships that will transfer the novel technologies to the market. - - - 2019-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Spain - - - BE-OPTICAL - - - H2020-MSCA-ITN-2015 - - - 675512 - - - - - FUNDACIO CENTRE DE REGULACIO GENOMICA - INSTITUT CURIE - EUVITRO SLU - THE FRANCIS CRICK INSTITUTE LIMITED - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - LEAD DISCOVERY CENTER GMBH - TECHNISCHE UNIVERSITAET DRESDEN - EUROPEAN MOLECULAR BIOLOGY LABORATORY - CHERRY BIOTECH - - - EUR 2 802 399,48 - - - A multidisciplinary approach to cell division: From human oocyte to synthetic biology - - - EUR 2 802 399,48 - - - Spain - France - Spain - United Kingdom - Germany - Germany - Germany - Germany - France - - - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The cell is the universal unit of living matter, and there cannot be propagation of life without cell division. DivIDe aims to investigate the mechanisms and principles of cell division and to reproduce them in vitro with - synthetic approaches. Crucial to cell division is the mitotic spindle, a structure whose main duty is the separation of chromosomes. The spindle is made of microtubules (MT), molecular motors, and MT-binding factors, some of which show astounding - complexity. The mitotic spindle is the one of the cellular structures that best represents the ability of biological matter to self-organize though arrays of dynamic protein-protein interactions. It rapidly assembles when cells enter mitosis, and it - disassembles, after sister chromatid separation and mitotic exit. The complexity and dynamic behaviour of the mitotic spindle captures the imagination of synthetic biologists and modellers. These “molecular engineers” try to understand and harness - the principles of self-organization to generate new biological structures endowed with the most typical features of biological matter, the ability to harness energy to do mechanical or chemical work. The emerging discipline of synthetic biology aims - to bring together modellers, physicists, and chemists, with biochemists, structural biologists and cell biologists. So does DivIDe, which will train a new generation of molecular engineers endowed with a strong basis in quantitative computational and - biochemical methods, and therefore capable of addressing cellular and molecular mechanisms. Furthermore, molecular engineering harbours industrial applications, and DivIDe will continuously provide results for potential exploitation by the three SME - partners. Training in management skills, conceptual and ethical thinking, communication and networking will complement the scientific offer. In summary, DivIDe will be able to teach an integrated package of skills and will train the molecular - biologists of the future. - - 2020-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Spain - - - DivIDe - - - H2020-MSCA-ITN-2015 - - - 675737 - - - - - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - STIFTUNG DEUTSCHES ELEKTRONEN-SYNCHROTRON DESY - ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - INSTITUT ZA NUKLEARNE NAUKE VINCA - TEL AVIV UNIVERSITY - AKADEMIA GORNICZO-HUTNICZA IM. STANISLAWA STASZICA W KRAKOWIE - THE UNIVERSITY OF LIVERPOOL - UNIVERSITE DE STRASBOURG - UNIVERSITE PARIS-SUD - INTER-UNIVERSITY RESEARCH INSTITUTE CORPORATION, HIGH ENERGY ACCELERATOR RESEARCH ORGANISATION - NATIONAL UNIVERSITY CORPORATION THEUNIVERSITY OF TOKYO - NATIONAL UNIVERSITY CORPORATION TOHOKU UNIVERSITY - NATIONAL UNIVERSITY CORPORATION KYUSHU UNIVERSITY - - - EUR 1 179 000 - - - Europe-Japan Accelerator Development Exchange Programme - - - EUR 2 281 500 - - - Switzerland - France - France - Spain - Germany - United Kingdom - United Kingdom - Serbia - Israel - Poland - United Kingdom - France - France - Japan - Japan - Japan - Japan - - - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The Europe-Japan Accelerator Development Exchange Programme (E-JADE) addresses the urgent need of exchange of ideas on R&D and implementation of future accelerators for particle physics. It does so by exchanging - accelerator scientists and experts between Europe and Japan. - - 2018-12-31, ongoing project | - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Switzerland - - - E-JADE - - - H2020-MSCA-RISE-2014 - - - 645479 - - - - - TECHNISCHE UNIVERSITAET MUENCHEN - TECHNISCHE UNIVERSITAET MUENCHEN - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 872 500 - - - Cell biology of myelin wrapping, plasticity and turnover - - - EUR 1 872 500 - - - Germany - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - The myelin sheath is a plasma membrane extension that is laid down in regular spaced segments along axons of the nervous system. In the central nervous system it is formed by oligodendrocytes that spirally wrap their plasma - membrane around axons to generate a highly abundant, tightly packed stack of membranes with unique structural properties. Previously, myelin has been regarded as an inert and purely insulating membrane, but it now appears that myelin is metabolically - active, providing metabolic support to the underlying axon and participating in information processing by modulating velocity and synchronicity of nerve impulses in neuronal networks. In addition, myelination is not limited to the period of early - post-natal development, but continuous into adulthood where it appears to be regulated by neuronal stimuli. This paradigm shift should be fuelled by new knowledge about myelin biology. Here, we plan to fill this gap by addressing the molecular basis - of myelin growth, plasticity and remodelling. We will determine the factors that determine whether and to what extent an axon will be myelinated or not, the forces that drive myelin around the axon, the structural basis of myelin plasticity and the - mechanisms of myelin turnover in the adult. We will test the hypothesis that microglia actively participate in myelin turnover by taking up myelin fragments that pinch off from the myelin sheath. To realize these aims we plan to pursue an integrative - and multidisciplinary approach by bringing together genetics, biochemistry, proteomics and imaging in various model systems. The innovation arises from the combination of high-resolution imaging with molecular approaches in different cell types to - obtain a unifying mechanistic understanding of myelin formation, maintenance and degradation. If successful, the project would not only explain how myelin is generated during brain development, but also give insight into how myelin plasticity could - fine-tune neuronal networks. - - 2020-07-31, ongoing project - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - Myelination - - - ERC-2014-CoG - - - 647168 - - - - - ISTITUTO NAZIONALE DI ASTROFISICA - UNIVERSITY OF LEICESTER - STICHTING SRON NETHERLANDS INSTITUTE FOR SPACE RESEARCH - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - NATIONAL OBSERVATORY OF ATHENS - THALES ALENIA SPACE ITALIA SPA - DANMARKS TEKNISKE UNIVERSITET - CENTRUM ASTRONOMICZNE IM. MIKOLAJAKOPERNIKA POLSKIEJ AKADEMII NAUK - UNIVERSITA DEGLI STUDI DI FERRARA - UNIVERSITA DEGLI STUDI DI PERUGIA - UNIVERSITE DE LIEGE - UNIVERSITA DEGLI STUDI DI GENOVA - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - Teknologian tutkimuskeskus VTT Oy - LANCASTER UNIVERSITY - CESKE VYSOKE UCENI TECHNICKE V PRAZE - UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN - UNIVERSITA DEGLI STUDI DI PALERMO - TARTU OBSERVATORY - ESTONIAN MINISTRY OF EDUCATION AND RESEARCH - UNIVERSIDAD DE ALICANTE - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - EBERHARD KARLS UNIVERSITAET TUEBINGEN - LABORATORIO DE INSTRUMENTACAO E FISICA EXPERIMENTAL DE PARTICULAS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSITE DE GENEVE - ISTITUTO NAZIONALE DI FISICA NUCLEARE - - - EUR 4 982 477 - - - Integrated Activities for the High Energy Astrophysics Domain - - - EUR 5 085 247 - - - Italy - United Kingdom - Netherlands - Germany - Greece - Italy - Denmark - Poland - Italy - Italy - Belgium - Italy - France - Finland - United Kingdom - Czech Republic - Ireland - Italy - Estonia - Spain - Spain - Germany - Portugal - France - Switzerland - Italy - - - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Jiri Matas - Tel.: +420 22435721 - Fax: +420 224357385 - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - - We propose a set of integrated Activities in the High Energy Astrophysics Domain (AHEAD) in response to the INFRAIA-2014-2015 call Research Infrastructures for High EnergyAstrophysics. - - 2019-02-28, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.2."> - - - INFRAIA-1-2014-2015 - Integrating and opening existing national and regional research infrastructures of European interest - - - RIA - Research and Innovation action - - - Italy - - - AHEAD - - - H2020-INFRAIA-2014-2015 - - - 654215 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - - - EUR 2 283 747 - - - Radiocarbon constraints for models of C cycling in terrestrial ecosystems: from process understanding to global benchmarking - - - EUR 2 283 747 - - - Germany - Germany - United States - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Higher or Secondary Education Establishments - - The overall goal of 14Constraint is to enhance the availability and use of radiocarbon data as constraints for process-based understanding of the age distribution of carbon in and respired by soils and ecosystems. Carbon - enters ecosystems by a single process, photosynthesis. It returns by a range of processes that depend on plant allocation and turnover, the efficiency and rate of litter decomposition and the mechanisms stabilizing C in soils. Thus the age - distribution of respired CO2 and the age of C residing in plants, litter and soils are diagnostic properties of ecosystems that provide key constraints for testing carbon cycle models. Radiocarbon, especially the transit of ‘bomb’ 14C created in the - 1960s, is a powerful tool for tracing C exchange on decadal to centennial timescales. 14Constraint will assemble a global database of existing radiocarbon data (WP1) and demonstrate how they can constrain and test ecosystem carbon cycle models. WP2 - will fill data gaps and add new data from sites in key biomes that have ancillary data sufficient to construct belowground C and 14C budgets. These detailed investigations will focus on the role of time lags caused in necromass and fine roots, as - well as the dynamics of deep soil C. Spatial extrapolation beyond the WP2 sites will require sampling along global gradients designed to explore the relative roles of mineralogy, vegetation and climate on the age of C in and respired from soil (WP3). - Products of this 14Constraint will include the first publicly available global synthesis of terrestrial 14C data, and will add over 5000 new measurements. This project is urgently needed before atmospheric 14C levels decline to below 1950 levels as - expected in the next decade. - - 2021-11-30, ongoing project - - - 2016-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - 14Constraint - - - ERC-2015-AdG - - - 695101 - - - - - UNIVERSITE DE STRASBOURG - BASF SE - KATHOLIEKE UNIVERSITEIT LEUVEN - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - UNIVERSITE DE MONS - HUMBOLDT-UNIVERSITAET ZU BERLIN - KARLSRUHER INSTITUT FUER TECHNOLOGIE - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - CONSIGLIO NAZIONALE DELLE RICERCHE - UNIVERSITY COLLEGE LONDON - SCRIBA NANOTECNOLOGIE SRL - - - EUR 3 826 359,72 - - - Integrated self-assembled SWITCHable systems and materials: towards responsive organic electronics – a multi-site innovative training action - - - EUR 3 826 359,72 - - - France - Germany - Belgium - Spain - Belgium - Germany - Germany - Germany - Italy - United Kingdom - Italy - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - iSwitch will offer top-level multi-disciplinary and supra-sectorial training to a pool of talented young researchers, involving contributions from different scientific and technological fields such as, supramolecular - chemistry, materials, nanoscience, physics and engineering. iSwitch’s appointees will be trained through lecture courses, dedicated international schools and workshops, topical conferences, secondments to other consortium nodes and an ambitious and - carefully planned research activities benefiting from the expertise of world-leading senior PIs and of younger but well-established PIs with outstanding track records in training and research. Additionally, iSwitch will generate new ground-breaking - S&T knowledge needed to obtain efficient and fast switching in supramolecular electro- and opto-active materials as a response to external stimuli. This will be accomplished via controlled self-assembly of multicomponent architectures - incorporating molecular switches, for fabricating responsive and multifunctional optoelectronic supramolecular devices. We are particularly interested in developing nano- and macro-scale switchable transistors and light-emitting devices as new - solutions to (nanoscale) multifunctional organic-based logics. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - France - - - iSwitch - - - H2020-MSCA-ITN-2014 - - - 642196 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA - - - EUR 2 492 500 - - - Quantum Spectroscopy: exploring new states of matter out of equilibrium - - - EUR 2 492 500 - - - Germany - Germany - Spain - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Higher or Secondary Education Establishments - - This project addresses the development of novel theoretical and computational tools that utilize the quantum nature of light to understand and control quantum phenomena in complex systems in and out of equilibrium. Some - examples of these processes include exciton-exciton interaction, quantum coherence, assisted energy and charge transport, photochemistry, and new states of matter. - - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - QSpec-NewMat - - - ERC-2015-AdG - - - 694097 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - KUNGLIGA TEKNISKA HOEGSKOLAN - - - EUR 1 500 000 - - - Dynamics and transport of quantum matter --- exploring the interplay of topology, interactions and localization - - - EUR 1 500 000 - - - Germany - Germany - Sweden - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Higher or Secondary Education Establishments - - Quantum matter is condensed matter which properties are dominated by the quantum nature of its constituents. The two most fundamental properties of quantum mechanics are interference and entanglement. How do these properties, - and their derivatives, show up in an experiment? And how does one control them? These are the fundamental questions addressed in this proposal. - - 2020-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - QUANTMATT - - - ERC-2015-STG - - - 679722 - - - - - UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN - JOHN INNES CENTRE - UNIVERSITAET FUER BODENKULTUR WIEN - UNIVERSITAT ZURICH - KOBENHAVNS UNIVERSITET - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - ENVIROTECH INNOVATIVE PRODUCTS LTD - JUSTUS-LIEBIG-UNIVERSITAET GIESSEN - LEIBNIZ - INSTITUT FUER PFLANZENGENETIK UND KULTURPFLANZENFORSCHUNG - TEAGASC - AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY - - - EUR 4 013 668,80 - - - CEREALPATH - Training in innovative and integrated control of cereal diseases - - - EUR 4 013 668,80 - - - Ireland - United Kingdom - Austria - Switzerland - Denmark - Ireland - Ireland - Germany - Germany - Ireland - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - - There is a massive and urgent effort needed to ensure security of food supply for the growing world population. This challenge of doubling crop yields by 2050 provides the motivation for this project, entitled Cereal Pathology - – training in innovative and integrated control of cereal diseases (CEREALPATH). Cereals are the most important source of human calories, but we lose billions of euro worth of grain annually due to diseases that reduce yield. CEREALPATH is a - multidisciplinary, multisectoral training programme built using the complimentary expertise from 22 participants from 8 European countries, including 7 Universities, 3 research institutes, 11 industry and one regulatory agency. The consortium will - combine and share expertise in different approaches to disease control to offer standardized, high quality doctoral training at an advanced level to 15 ESRs. CEREALPATH will expose researchers to research and innovation in both industry and academia. - The training equips researchers with the skills and opportunities to develop innovative methods contributing to integrated disease control programmes, thus matching their potential to the jobs of the future and helping Europe and the world meet the - critical need of global food security. - - 2019-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Ireland - - - CEREALPATH - - - H2020-MSCA-ITN-2015 - - - 674964 - - - - - UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN - UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN - THE UNIVERSITY OF WARWICK - UNIVERSITY OF BRISTOL - - - EUR 1 579 298,75 - - - Integrable Random Structures - - - EUR 1 579 298,75 - - - Ireland - Ireland - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The last few years have seen significant advances in the discovery and development of integrable models in probability, especially in the context of random polymers and the Kardar-Parisi-Zhang (KPZ) equation. Among these are - the semi-discrete (O'Connell-Yor) and log-gamma (Seppalainen) random polymer models. Both of these models can be understood via a remarkable connection between the geometric RSK correspondence (a geometric lifting, or de-tropicalization, of the - classical RSK correspondence) and the quantum Toda lattice, the eigenfunctions of which are known as Whittaker functions. This connection was discovered by the PI and further developed in collaboration with Corwin, Seppalainen and Zygouras. In - particular, we have recently introduced a powerful combinatorial framework which underpins this connection. I have also explored this connection from an integrable systems point of view, revealing a very precise relation between classical, quantum - and stochastic integrability in the context of the Toda lattice and some other integrable systems. The main objectives of this proposal are (1) to further develop the combinatorial framework in several directions which, in particular, will yield a - wider family of integrable models, (2) to clarify and extend the relation between classical, quantum and stochastic integrability to a wider setting, and (3) to study thermodynamic and KPZ scaling limits of Whittaker functions (and associated - measures) and their applications. The proposed research, which lies at the interface of probability, integrable systems, random matrices, statistical physics, automorphic forms, algebraic combinatorics and representation theory, will make novel - contributions in all of these areas. - - 2020-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Ireland - - - IntRanSt - - - ERC-2014-ADG - - - 669306 - - - - - INSTITUTO DE MEDICINA MOLECULAR - Faculdade de Farmácia da Universidade de Lisboa - UNIVERSITY COLLEGE LONDON - UNIVERSITAET ULM - UNIVERSIDAD DE LA RIOJA - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - INSTITUT CURIE - UNIVERSITAT WIEN - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 2 542 770,72 - - - A training network for the chemical site-selective modification of proteins: Preparation of the next-generation of therapeutic chemically-defined protein conjugates - - - EUR 2 542 771,03 - - - Portugal - Portugal - United Kingdom - Germany - Spain - United Kingdom - France - Austria - Germany - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - ProteinConjugates is an inter- and multi-disciplinary network for the education of talented young scientists who will learn how to rationally design and construct the next generation of chemically-defined and innovative - protein drug-conjugates for the targeted treatment of serious conditions such as cancer or rheumatoid arthritis. A complementary interaction between academy and pharmaceutical industry is at the centre of such a network, which involves 8 academic - groups and 1 SME partner as beneficiaries, and 2 leading European industrial partner organizations that will host secondments while providing training. The combined expertise of the beneficiaries and industrial partners in synthesis of complex - molecules, molecular dynamics, supramolecular self-assembly, site-selective chemical protein modification, protein/antibody engineering, cancer therapeutics and drug development together with the experience in project management and training of PhDs - and Postdocs of the PIs, will create a multidisciplinary environment where 10 young researchers can foster their knowledge and skills while developing the most innovative ideas in the emerging fields of chemical site-selective protein modification - and protein biotherapeutics. Exposure to the highly dynamic and multidisciplinary ProteinConjugates environment will contribute to the education of the next generation of leaders in the emerging field of protein biotherapeutics, a key area of - research and drug development for Europe's competitiveness. - - 2019-10-31, ongoing project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Portugal - - - ProteinConjugates - - - H2020-MSCA-ITN-2015 - - - 675007 - - - - - CITY UNIVERSITY OF LONDON - CITY UNIVERSITY OF LONDON - COPENHAGEN BUSINESS SCHOOL - - - EUR 1 739 387 - - - Corporate Arbitrage and CPL Maps: Hidden Structures of Controls in the Global Economy - - - EUR 1 739 387 - - - United Kingdom - United Kingdom - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Political science conceptualises state-market relations as balancing acts between the public sphere (the state or government) and the private sphere (the market, dominated by large corporate bodies). The expansion of the - global market has been led by the rise of large and highly mobile multinational firms. Since many of these companies command turnover comparable to the GDP of middle size states, globalisation is often seen as a global shift of power from states to - markets, where corporate power stems from centralisation of resources, capital and structural influence over politics and society. - - - 2020-11-30, ongoing project - - - 2016-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - CORPLINK - - - ERC-2015-AdG - - - 694943 - - - - - UNIVERSITE LIBRE DE BRUXELLES - UNIVERSITE LIBRE DE BRUXELLES - - - EUR 2 250 000 - - - Role of Apolipoproteins L in immunity and disease - - - EUR 2 250 000 - - - Belgium - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Work conducted in my laboratory on the trypanosome killing factor of human serum led to the identification - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Belgium - - - APOLs - - - ERC-2014-ADG - - - 669007 - - - - - UNIVERSITEIT UTRECHT - UNIVERSITAT DE GIRONA - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - LEIBNIZ - INSTITUT FUR KATALYSE EV AN DER UNIVERSITAT ROSTOCK - UNIVERSITAET BERN - DSM CHEMICAL TECHNOLOGY R & D BV - KATHOLIEKE UNIVERSITEIT LEUVEN - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - UNIVERSITE DE BRETAGNE OCCIDENTALE - - - EUR 3 318 634,08 - - - Non-Noble Metal Catalysis - NoNoMeCat - - - EUR 3 318 634,08 - - - Netherlands - Spain - Switzerland - Germany - Switzerland - Netherlands - Belgium - Germany - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Higher or Secondary Education Establishments - - Transition metal catalysts are formidable tools towards greener chemistry, allowing for low-waste, energy-efficient, and selective reactions. However, the noble metals (Ru, Os, Rh, Ir, Pd, Pt) that are currently most common in - homogeneous catalysts suffer from high toxicity and environmental impact in addition to their scarcity and ensuing high cost. First-row metals (Mn, Fe, Co, Ni, Cu) are emerging as environmentally benign alternatives, but to this day rarely equal the - performance of their noble counterparts. The NoNoMeCat network aims at providing excellent and structured interdisciplinary training to a generation of young researchers in the field of Non-Noble Metal homogeneous Catalysis who will push the - boundaries of the field in terms of catalyst stability, selectivity, mechanistic understanding, and scalability. These challenges are addressed in three areas of high fundamental and practical significance: the oxidation of hydrocarbons, the - formation of new C-X bonds (C-C, C-N) bonds through cross-coupling reactions, and clean energy production. NoNoMeCat will enrol 14 Early Stage Researchers (ESRs) who will receive structured training in experimental and theoretical aspects of - non-noble metal chemistry as well as transferable skills such as research integrity, scientific communication and public outreach. Tight integration of non-academic partners will expose all ESRs to aspects of both fundamental interdisciplinary - research and industrial application, paving the way for long-standing intersectorial collaborations. - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Netherlands - - - NoNoMeCat - - - H2020-MSCA-ITN-2015 - - - 675020 - - - - - THE UNIVERSITY OF BIRMINGHAM - FEMTONICS KUTATO ES FEJLESZTO KORLATOLT FELELOSSEGU TARSASAG - MAGYAR TUDOMANYOS AKADEMIA WIGNER FIZIKAI KUTATOKOZPONT - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - PECSI TUDOMANYEGYETEM - UNIVERSITY OF PECS - - - EUR 4 271 481,25 - - - Visual genetics: establishment of a new discipline to visualize neuronal nuclear functions in real-time in intact nervous system by 4D Raman spectroscopy - - - EUR 4 271 481,25 - - - United Kingdom - Hungary - Hungary - Germany - Hungary - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Higher or Secondary Education Establishments - - Due to technical constraints the observation and analysis of endogenous transcriptional processes in living and functioning organisms is not feasible today. Therefore our understanding of the nuclear processes and the options - to diagnose or intervene at genetic level is seriously constrained. Our proposal offers a cutting-edge technique to overcome this limitation. The aim is to visualize nuclear processes in intact brain in real-time leading to a new high-tech product - development, prototype scientific equipment at the research institutes and in the long run new tools to study and cure human diseases. The main objectives are to: 1) develop Stimulated Raman Spectroscopy (SRS)-based technologies to visualize - endogenous transcription at single cell and single gene level; 2) develop tools for loading alkyne-tagged nucleosides and nucleotide analogues into neurons; 3) distinguish neuron types without labelling by SRS; 4) track transcription processes in - intact brain with high temporal and spatial resolution; 5) study link between single gene function and behavior; 5) develop and commercialise a 4D-SRS microscope for broad range of applications. The combination of label-free neuron mapping and - visualization of nuclear activity at single gene level provides a new level of information of the structural and functional organization of the brain. - - 2019-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-1-2014 - FET-Open research projects - - - RIA - Research and Innovation action - - - United Kingdom - - - NEURAM - - - H2020-FETOPEN-2014-2015-RIA - - - 712821 - - - - - TECHNISCHE UNIVERSITAET WIEN - PHYSIKALISCH-TECHNISCHE BUNDESANSTALT - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - JYVASKYLAN YLIOPISTO - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - TOPTICA PHOTONICS AG - - - EUR 3 970 327,50 - - - Towards a nuclear clock with Thorium-229 - - - EUR 3 970 327,50 - - - Austria - Germany - Germany - Germany - Finland - Germany - Germany - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Atomic clocks are the backbone of our modern communication and navigation technology, e.g. through the global positioning system (GPS). Improving these clocks will open up exciting new applications in geodesy, fleet tracking, - autonomous vehicles, augmented reality and shed light on some of the most fundamental questions in research. - - 2019-05-31, ongoing project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-1-2014 - FET-Open research projects - - - RIA - Research and Innovation action - - - Austria - - - nuClock - - - H2020-FETOPEN-2014-2015-RIA - - - 664732 - - - - - KOBENHAVNS UNIVERSITET - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - UNIVERSITEIT UTRECHT - THERMO FISHER SCIENTIFIC (BREMEN) GMBH - - - EUR 3 672 625 - - - Mass spectrometric technology for next generation proteomics in systems medicine - - - EUR 5 038 875 - - - Denmark - Germany - Netherlands - Germany - - - Higher or Secondary Education Establishments - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Systems medicine designates the application of global approaches to human health and disease. Genomic technologies, especially next-generation sequencing, are already pioneering this new area. There is an urgent need to - advance proteomics technologies to a similar level. This will help revolu¬tionize diagnosis and prognosis based on the expression levels and modifications of proteins in cells, tissues, organoids or body fluids. Our vision is to make mass - spectrometry so robust and powerful that it will be present in every biological laboratory and in every clinic. - - - 2019-11-30, ongoing project - - - 2015-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-1-2014 - FET-Open research projects - - - RIA - Research and Innovation action - - - Denmark - - - MSmed - - - H2020-FETOPEN-2014-2015-RIA - - - 686547 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN - - - EUR 1 338 500 - - - Wavefunctions for strongly correlated systems - - - EUR 1 338 500 - - - Germany - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Higher or Secondary Education Establishments - - Strongly correlated quantum systems, which are at the heart of many open problems in condensed matter, - - 2020-02-29, ongoing project - - - 2015-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - WASCOSYS - - - ERC-2014-STG - - - 636201 - - - - - LEIBNIZ-INSTITUT FUR RAUMBEZOGENE SOZIALFORSCHUNG (IRS) EV - UNIWERSYTET IM. ADAMA MICKIEWICZA W POZNANIU - ROSKILDE UNIVERSITET - UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK - BALLYHOURA DEVELOPMENT LTD - LEIBNIZ-INSTITUT FUR LANDERKUNDE EV - University of the Aegean-Research Unit - OTELO EGEN - INSTITUTO UNIVERSITARIO DE LISBOA - - - EUR 2 529 895,32 - - - Social Enterpreneurship in Structurally Weak Rural Regions: Analysing Innovative Troubleshooters in Action - - - EUR 2 529 895,32 - - - Germany - Poland - Denmark - Ireland - Ireland - Germany - Greece - Austria - Portugal - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - Structurally weak rural regions are faced with major social and economic problems. In comparison to urban or intermediate regions, predominantly rural regions are economically less productive and they provide a less extensive - scope of desired goods and services. As a consequence, the regions experience a loss of inhabitants, especially of young and highly skilled people. Thus, downward spirals are set in motion that further reduce economic opportunities and prevent rural - regions from overcoming their structural deficits. - - - 2020-11-30, ongoing project - - - 2016-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - RURACTION - - - H2020-MSCA-ITN-2016 - - - 721999 - - - - - WEIZMANN INSTITUTE OF SCIENCE - BAR ILAN UNIVERSITY - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - UNIVERSITE DE GENEVE - UNIVERSIDAD CARLOS III DE MADRID - AUGMANITY NANO LTD - - - EUR 3 979 069 - - - NanoSmells: Artificial remote-controlled odorants - - - EUR 3 979 069 - - - Israel - Israel - Germany - Switzerland - Spain - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Despite years of promise, an odor-emitting component in devices such as televisions, phones, computers and more has yet to be developed. Two major obstacles in the way of such development are poor understanding of the - olfactory code (the link between odorant structure, neural activity, and odor perception), and technical inability to emit odors in a reversible manner. Here we propose a novel multidisciplinary path to solving this basic scientific question (the - code), and in doing so generate a solution to the technical limitation (controlled odor emission). The Bachelet lab will design DNA strands that assume a 3D structure that will specifically bind to a single type of olfactory receptor and induce - signal transduction. These DNA-based "artificial odorants" will be tagged with a nanoparticle that changes their conformation in response to an external electromagnetic field. Thus, we will have in hand an artificial odorant that is remotely - switchable. The Hansson lab will use tissue culture cells expressing insect olfactory receptors, functional imaging, and behavioral tests to validate the function and selectivity of these switchable odorants in insects. The Carleton lab will use - imaging in order to investigate the patterns of neural activity induced by these artificial odorants in rodents. The Sobel lab will apply these artificial odorants to the human olfactory system, and measure perception and neural activity following - switching the artificial smell on and off. Finally, given a potential role for olfactory receptors in skin, the Del Rio lab will test the efficacy of these artificial odorants in promoting wound healing. At the basic science level, this approach may - allow solving the combinatorial code of olfaction. At the technology level, beyond novel pharmacology, we will provide proof-of-concept for countless novel applications ranging from insect pest-control to odor-controlled environments and - odor-emitting devices such as televisions, phones, and computers. - - 2019-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-1-2014 - FET-Open research projects - - - RIA - Research and Innovation action - - - Israel - - - NanoSmell - - - H2020-FETOPEN-2014-2015-RIA - - - 662629 - - - - - ECRIN EUROPEAN CLINICAL RESEARCH INFRASTRUCTURE NETWORK - THE UNIVERSITY OF LIVERPOOL - CONSORZIO PER VALUTAZIONI BIOLOGICHE E FARMACOLOGICHE - STICHTING KATHOLIEKE UNIVERSITEIT - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - HELSINGIN JA UUDENMAAN SAIRAANHOITOPIIRIN KUNTAYHTYMÄ - FUNDACIO SANT JOAN DE DEU - SWISS CLINICAL TRIAL ORGANISATION VEREIN - KAROLINSKA INSTITUTET - HELSE BERGEN HF*HAUKELAND UNIVERSITY HOSPITAL - TARTU ULIKOOL - ARISTOTELIO PANEPISTIMIO THESSALONIKIS - OKIDS GMBH - THE NATIONAL CHILDREN'S RESEARCH CENTRE - VERENIGING SAMENWERKENDE OUDER- EN PATIENTENORGANISATIES - - - EUR 3 296 000 - - - Paediatric Clinical Research Infrastructure Network - - - EUR 3 296 000 - - - France - United Kingdom - Italy - Netherlands - France - Finland - Spain - Switzerland - Sweden - Norway - Estonia - Greece - Austria - Ireland - Netherlands - - - Other - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Other - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - Other - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - Children’s health is a major societal challenge for Europe and the world, requiring development of paediatric medicines and treatments strategies based on evidence derived from clinical trials demonstrating efficacy and safety - in infants and children, rather than on uncritical extrapolation from adult data (over 50 % of the medicines used for children had not been tested in this specific age group). - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-03-2016-2017 - Individual support to ESFRI and other world-class research infrastructures - - - CSA - Coordination and support action - - - France - - - PedCRIN - - - H2020-INFRADEV-2016-1 - - - 731046 - - - - - STIFTUNG DEUTSCHES ELEKTRONEN-SYNCHROTRON DESY - UNIVERSITE DE GENEVE - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - KARLSRUHER INSTITUT FUER TECHNOLOGIE - - - EUR 886 500 - - - SENSE - a roadmap for the ideal low light level sensor development - - - EUR 886 500 - - - Germany - Switzerland - Germany - Germany - - - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Higher or Secondary Education Establishments - - Over the last decade substantial improvements were made in the technologies for low light-level detection. It is expected that the coming years may bring a technology revolution in this emerging FET-relevant topic. Various - European research groups have played and will play an important role in further advancing this technology since low light-level detection is very important for a lot of research projects and upcoming research infrastructures. Indeed, R&D in this - technology is growing and new groups all over Europe and world-wide are getting involved. However, a coordination of these groups – especially in Europe – is currently missing; while competition is often speeding up developments especially in the - prototyping together with industry, duplication in testing and evaluating available devices for research projects is unfortunately standard. - - 2019-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-3-2015 - Coordination and Support Activities - - - CSA - Coordination and support action - - - Germany - - - SENSE - - - H2020-FETOPEN-2015-CSA - - - 713171 - - - - - TECHNISCHE UNIVERSITAET MUENCHEN - UNIVERSITA DEGLI STUDI DI TRENTO - UNIVERSITY OF DURHAM - STIFTUNG FRANKFURT INSTITUTE FOR ADVANCED STUDIES - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - RSK TEHNOLOGII ZAO - BAYERISCHE FORSCHUNGSALLIANZ BAVARIAN RESEARCH ALLIANCE GMBH - - - EUR 2 795 000 - - - An Exascale Hyperbolic PDE Engine - - - EUR 2 872 500 - - - Germany - Italy - United Kingdom - Germany - Germany - Russia - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - - Many aspects of our life, but also cutting-edge research questions, hinge on the solution of large systems of partial differential equations expressing conservation laws. Such equations are solved to compute accurate weather - forecast, complex earthquake physics, hematic flows in patients, or the most catastrophic events in the universe. Yet, our ability to exploit the predictive power of these models is still severely limited by the computational costs of their solution. - Thus, the simulation of earthquakes and their induced hazards is not yet accurate enough to prevent human losses. And our ability to model astrophysical objects is still insufficient to explain our observations. - - 2019-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.2."> - - - FETHPC-1-2014 - HPC Core Technologies, Programming Environments and Algorithms for Extreme Parallelism and Extreme Data Applications - - - RIA - Research and Innovation action - - - Germany - - - ExaHyPE - - - H2020-FETHPC-2014 - - - 671698 - - - - - UNIVERSITY COLLEGE LONDON - DEUTSCHES FORSCHUNGSZENTRUM FUR KUNSTLICHE INTELLIGENZ GMBH - UNIVERZITA KARLOVA - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - STUDIO GOBO LIMITED - UNIVERSITAT DES SAARLANDES - Institute of Science and Technology Austria - EDINBURGH NAPIER UNIVERSITY - - - EUR 3 264 733 - - - Distributed 3D Object Design - - - EUR 3 264 733 - - - United Kingdom - Germany - Czech Republic - Germany - United Kingdom - Germany - Austria - United Kingdom - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Corinna Hahn - Tel.: +49 681 95 92 3362 - Fax: +49 681 95 92 3370 - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The DISTRO network brings together leading laboratories in Visual Computing and 3D Computer Graphics research across Europe with the aim of training a new generation of scientists, technologists, and entrepreneurs that will - move Europe into a leading role in the scientific and technological innovation in the area of casual, distributed 3d object design and customization. - - 2018-12-31, ongoing project | - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - DISTRO - - - H2020-MSCA-ITN-2014 - - - 642841 - - - - - TARTU ULIKOOL - - - EUR 228 421,80 - - - Socrates and Plato on Epistemic Authority - - - EUR 228 421,80 - - - Estonia - - - Higher or Secondary Education Establishments - - It often happens that we accept as true what other people tell us, and by doing so, we acquire knowledge about the world. We trust each other, and we often grant teachers and experts authority over our beliefs. The - inter-subjective nature of belief formation has recently moved into the very center of epistemology. However, it is rarely mentioned that the reflection on the role of other people in our knowledge-acquisition has a distinguished historical pedigree, - one that still deeply affects the way think about these issues. In particular, the Greek philosophers’ treatment of the notions of authority, trust, and disagreement has exerted strong influence on the subsequent history of philosophy. Up to now, - however, there has been no systematic study of this important aspect of Greek thought. This project, “Socrates and Plato on Epistemic Authority”, focuses on the role attributed to what philosophers call “epistemic authority” (i.e. authority over - belief) in knowledge acquisition and belief formation in the classical era of Ancient Greek philosophy (esp. in Socrates and Plato). Thus, the project aims to improve the understanding of Greek epistemology and to offer a historical background and an - independent contribution to a central epistemological topic. - - 2018-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Estonia - - - SPEA - - - H2020-MSCA-IF-2014 - - - 659241 - - - - - INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU GEOLOGIE SI GEOECOLOGIE MARINA-GEOECOMAR - INSTITUTUL NATIONAL DE CERCERTARE DEZVOLTARE PENTRU STIINTE BIOLOGICE RA - Unitatea Executiva pentru Finantarea Invatamantului Superior, a Cercetarii, Dezvoltarii si Inovarii - Agentia de Administrare a Retelei Nationale de Informatica Pentru Educatie si Cercetare - WasserCluster Lunz - Biologische Station GmbH - BULGARIAN ACADEMY OF SCIENCES - USTAV VYZKUMU GLOBALNI ZMENY AV CR VVI - EUROPPORTUNITIES OU - UNIVERSITE DE LORRAINE - Bundesanstalt fuer Gewaesserkunde - HELMHOLTZ-ZENTRUM GEESTHACHT ZENTRUM FUR MATERIAL- UND KUSTENFORSCHUNG GMBH - HELLENIC CENTRE FOR MARINE RESEARCH - SZECHENYI ISTVAN UNIVERSITY - UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK - CONSIGLIO NAZIONALE DELLE RICERCHE - CORILA - CONSORZIO PER IL COORDINAMENTO DELLE RICERCHE INERENTI AL SISTEMA LAGUNARE DI VENEZIA - INTEGRATED CARBON OBSERVATION SYSTEM EUROPEAN RESEARCH INFRASTRUCTURE CONSORTIUM - EUROPEAN MULTIDISCIPLINARY SEAFLOORAND WATER COLUMN OBSERVATORY - EUROPEAN RESEARCH INFRASTRUCTURE CONSORTIUM (EMSO ERIC) - INSTITUTUL DE CHIMIE ACADEMIA DE STIINTE A MOLDOVEI - STICHTING DELTARES - UNIVERSITAT POLITECNICA DE CATALUNYA - AUTORIDAD PORTUARIA DE SEVILLA - STICHTING IHE DELFT - THE UNIVERSITY OF STIRLING - THE UNIVERSITY OF BIRMINGHAM - NATURAL ENVIRONMENT RESEARCH COUNCIL - PLYMOUTH MARINE LABORATORY - Odessa State Environmental University - DEMOCRITUS UNIVERSITY OF THRACE - - - EUR 3 996 405 - - - PREPARATORY PHASE FOR THE PAN-EUROPEAN RESEARCH INFRASTRUCTURE DANUBIUS–RI “THE INTERNATIONAL CENTRE FOR ADVANCED STUDIES ON RIVER-SEA SYSTEMS - - - EUR 3 996 405 - - - Romania - Romania - Romania - Romania - Austria - Bulgaria - Czech Republic - Estonia - France - Germany - Germany - Greece - Hungary - Ireland - Italy - Italy - Finland - Italy - Moldova - Netherlands - Spain - Spain - Netherlands - United Kingdom - United Kingdom - United Kingdom - United Kingdom - Ukraine - Greece - - - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Other - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - DANUBIUS-PP is a three-year project to raise DANUBIUS-RI (International Centre for Advanced Studies on River-Sea Systems) to the legal, financial and technical maturity required for successful implementation and development. - DANUBIUS-RI is a pan-European distributed research infrastructure (RI) building on existing expertise to support interdisciplinary research on river-sea (RS) systems, spanning the environmental, social and economic sciences. It will provide access to - a range of RS systems, facilities and expertise, a ‘one-stop shop’ for knowledge exchange, access to harmonised data, and a platform for interdisciplinary research, education and training. - - 2019-11-30, ongoing project - - - 2016-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-02-2016 - Preparatory Phase and support to early phase of ESFRI projects - - - CSA - Coordination and support action - - - Romania - - - DANUBIUS-PP - - - H2020-INFRADEV-2016-2 - - - 739562 - - - - - UNIVERSITA CA' FOSCARI VENEZIA - - - EUR 262 269 - - - The Catholic Charismatic Renewal (CCR): an Historical Analysis Between US and Europe - - - EUR 262 269 - - - Italy - - - Higher or Secondary Education Establishments - - The research project aims to analyze the history of the Catholic Charismatic Renewal (CCR), a spiritual awakening movement which was founded in 1967 in the United States of America within the Catholic Church and which spread - rapidly throughout the world, so much so that today its has more than 120 million members. The proposal intends to focus on three specific objectives: - - 2019-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Italy - - - CAT-CAM - - - H2020-MSCA-IF-2014 - - - 654994 - - - - - UNIVERSITA DEGLI STUDI DI CAMERINO - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - BIOMOLECULAR RESEARCH GENOMICS SRL - UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA - EPIGENETIKS GENETIK BIYOINFORMATIK YAZILIM AS - ELVESYS SAS - - - EUR 337 500 - - - Advanced bioinformatics for genome and metagenome analyses and discovery of novel biocatalists from extremophiles: implications for improving industrial bioprocesses - - - EUR 337 500 - - - Italy - United Kingdom - Italy - Italy - Turkey - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The aim of this proposal is to acquire new insights about the mechanisms of environmental adaptation, particularly for cold-adapted organisms, and to discover novel metabolic pathways and enzymes with potential industrial - value. We intend to accomplish this goal by establishing a collaboration and a knowledge-exchange network between industrial and academic partners aiming at developing bioinformatic tools for genomic analysis and biotechnology tools for directed - evolution. The partners present high complementarity: UNICAM holds genomic sequences from psychrophilic and mesophilic ciliates that need to be annotated and analysed. Sabanci provides environmental samples for the isolation and characterization of - new extremophiles. CAMBRIDGE provides the know-how for the discovery of new metabolic pathways valuable for understanding environmental adaptation. BMR Genomics and COMSATS possess all the facilities for genome sequencing and annotation and - bioinformatic expertise with the purpose of developing new tools to analyse genomes of microorganisms from extreme environment. UNIMIB owns the facilities for the heterologous expression of gene sequences in bacteria and yeasts and technologies to - assess and implement the properties of novel enzymes towards industrial application. We are confident that the establishment of the international research network proposed, with its synergistic effects, will significantly contribute to push all the - involved laboratories to the top level in the field of production of active biomolecules and in the discovery of mechanisms of molecular adaptation under extreme environmental conditions. These discoveries may help the manufacturing of a new - generation of ordinary facilities, as cleaning agents, biofuels, with a significant impact on the everyday life of European citizens. - - 2018-11-30, ongoing project - - - 2014-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Italy - - - MeTABLE - - - H2020-MSCA-RISE-2014 - - - 645693 - - - - - STICHTING WAGENINGEN RESEARCH - DEUTSCHES INSTITUT FUER LEBENSMITTELTECHNIK - EUROPEAN FOOD INFORMATION RESSOURCE AISBL - INSTITUT JOZEF STEFAN - WAGENINGEN UNIVERSITY - UNIVERSITY OF SURREY - RISE RESEARCH INSTITUTES OF SWEDEN AB - AALBORG UNIVERSITET - DE LA CUEVA GONZALEZ COTERA JAVIER - Eidgenössische Technische Hochschule Zürich - EUROPEAN FOOD INFORMATION COUNCIL AISBL - INSTITUTE OF FOOD RESEARCH - CONSIGLIO NAZIONALE DELLE RICERCHE - CENTRE EUROPEEN POUR LA NUTRITION ET LA SANTE - AALTO-KORKEAKOULUSAATIO - GS1 DENMARK FORENING - - - EUR 2 997 283,25 - - - Research Infrastructure on Consumer Health and Food Intake using E-science with Linked Data Sharing - - - EUR 3 085 299,58 - - - Netherlands - Germany - Belgium - Slovenia - Netherlands - United Kingdom - Sweden - Denmark - Spain - Switzerland - Belgium - United Kingdom - Italy - France - Finland - Denmark - - - Research Organisations - Research Organisations - Other - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Other - Research Organisations - Research Organisations - Other - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - RICHFIELDS - - 2018-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-1-2014 - Design studies - - - RIA - Research and Innovation action - - - Netherlands - - - RICHFIELDS - - - H2020-INFRADEV-1-2014-1 - - - 654280 - - - - - POLITECNICO DI MILANO - FORSCHUNGSVERBUND BERLIN EV - LUNDS UNIVERSITET - STIFTUNG DEUTSCHES ELEKTRONEN-SYNCHROTRON DESY - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - AARHUS UNIVERSITET - AMPLITUDE TECHNOLOGIES SA - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - FEMTOLASERS PRODUKTIONS GMBH - ALBERT-LUDWIGS-UNIVERSITAET FREIBURG - - - EUR 3 896 869,64 - - - Molecular Electron Dynamics investigated by IntensE Fields and Attosecond Pulses - - - EUR 3 896 869,64 - - - Italy - Germany - Sweden - Germany - Germany - Denmark - France - France - Greece - Austria - Germany - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - The interaction of matter with light is one of the most fundamental processes occurring in nature with countless scientific and technological applications. In recent years, the continuing development of intense, ultrashort, - coherent light sources from the mid-infrared (mid-IR) to the extreme ultraviolet (XUV) spectral range has opened new possibilities for the investigation of this interaction in new and complementary domains. In both the IR and XUV regimes, molecules - and clusters of atoms interacting with light exhibit (correlated) multi-electron dynamics evolving on the few femtosecond (1 fs=10-15 s) to attosecond (1 as=10-18 s) timescale. Several experimental and theoretical investigations suggest that - ultrafast multielectronic processes might be fundamental in determining the behaviour of molecules and clusters, and that understanding these phenomena might offer new perspectives on processes occurring on “slower” timescales, such as bond-breaking - in complex molecules and Coulomb explosion in charged clusters. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Italy - - - MEDEA - - - H2020-MSCA-ITN-2014 - - - 641789 - - - - - AARHUS UNIVERSITET - MEDIZINISCHE HOCHSCHULE HANNOVER - HELMHOLTZ-ZENTRUM FUER INFEKTIONSFORSCHUNG GMBH - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - UNIVERSITAIR MEDISCH CENTRUM UTRECHT - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - UNIVERSITA DEGLI STUDI DI TORINO - AARHUS UNIVERSITETSHOSPITAL - Janssen Vaccines and Prevention B.V. - - - EUR 3 961 943,28 - - - Training network providing cutting-EDGE knowlEDGE on Herpes Virology and Immunology - - - EUR 3 961 943,28 - - - Denmark - Germany - Germany - United Kingdom - Netherlands - Germany - Italy - Denmark - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Herpesviruses are widely spread, and cause life-long infections. Most individuals carry multiple herpesviruses, which can cause severe diseases, especially in children, immunocompromised individuals, and elderly. There are - currently no safe vaccines against herpesvirus infections and current treatments are not satisfactory. With new insights into the molecular basis for diseases caused by immunodeficiency, and with the increasing numbers of elderly in Europe, there is - now an unmet demand for improved treatments of herpesvirus infections. Combined with the progress in basic herpesvirus research, this calls for education of a new generation of scientists with strong research skills, advanced insights into disease - mechanisms, and understanding of how industry brings innovative research into the market. In this application we propose an interactive education program for early stage researchers (ESR) in leading European laboratories, hospitals, and biotech - companies. The focus will be on the virology and immunology of herpesvirus infections in the context of basic research as well as application of research-acquired knowledge. Our program will prepare the ESRs to manage goal-oriented interactions - between academia, the clinics, and the biotech industry. The ESRs will acquire broad theoretical and methodological expertises involving several sectors to obtain the skills required for overcoming the cultural gaps From Bench to Bedside and From - Discovery to Innovation. This can only be achieved through a network-based approach. We propose to develop a platform to educate the next generation of scientists to solve the outstanding problems in prevention and treatment of herpesvirus - infections. The ESRs will be ideally trained to translate cutting-edge discoveries to novel products and to innovative treatment serving the European people, and hence to improve handling of present and emerging health challenges, as well as to - foster the European biopharmaceutical industry sector. - - 2020-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Denmark - - - EDGE - - - H2020-MSCA-ITN-2015 - - - 675278 - - - - - NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - ECOLE NATIONALE DES PONTS ET CHAUSSEES - ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS - TECHNOLOGIKO PANEPISTIMIO KYPROU - RISA SICHERHEITSANALYSEN GMBH - UAB METIS BALTIC - EXUS SOFTWARE LTD - - - EUR 1 845 000 - - - Transforming Intangible Folkloric Performing Arts into Tangible Choreographic Digital Objects - - - EUR 1 845 000 - - - Greece - United Kingdom - France - Greece - Cyprus - Germany - Lithuania - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Intangible Cultural Heritage (ICH) content means "the practices, representations, expressions, knowledge, skills – as well as the instruments, objects, artefacts and cultural spaces associated therewith". Although, ICH - content, especially traditional folklore performing arts, is commonly deemed worthy of preservation by UNESCO (Convention for the Safeguarding of ICH) and the EU Treaty, most of the current research efforts are on the focus is on tangible cultural - assets, while the ICH content has been overlooked. The primary difficulty stems by the complex structure of ICH, its dynamic nature, the interaction among the objects and the environment, as well as emotional elements (e.g., the way of expression and - dancers' style). TERPSICHORE aims to study, analyse, design, research, train, implement and validate an innovative framework for affordable digitization, modelling, archiving, e-preservation and presentation of ICH content related to folk dances, in - a wide range of users (dance professionals, dance teachers, creative industries and general public). The project targets at integrating the latest innovative results of photogrammetry, computer vision, semantic technologies, time evolved modeling, - combined with the story telling and folklore choreography. An important output of the project will be a Web based cultural server/viewer with the purpose to allow user’s interaction, visualization, interface with existing cultural libraries - (EUROPEANA) and enrichment functionalities to result in virtual surrogates and media application scenarios that release the potential economic impact of the ICH. The final product will support a set of services such as virtual/augmented reality, - social media, interactive maps, presentation and learning of European Folk dances with tremendous impact on the European society, culture and tourism. - - 2020-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Greece - - - Terpsichore - - - H2020-MSCA-RISE-2015 - - - 691218 - - - - - LANCASTER UNIVERSITY - UNIVERSITY OF CYPRUS - UNIVERSITY OF YORK - - - EUR 904 500 - - - Advancing the state of the art of MIMO: the key to the successful evolution of wireless networks - - - EUR 904 500 - - - United Kingdom - Cyprus - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The world is experiencing an explosion in wireless broadband usage and global wireless data traffic is expected to grow at an annual rate of 78% through 2016. Multiple-input multiple-output (MIMO) technologies have been - envisioned as a key to the successful deployment of next generation networks, which are challenged by many practical constraints, such as spectrum scarcity and dynamical wireless environments. The ATOM project will set an ambitious research agenda to - fully exploit the potentials of MIMO technologies for revolutionizing wireless networks. Particularly the overall objective of ATOM is to accelerate the transfer and deployment of research knowledge between European countries and third-country - partners in order to provide a framework of advanced MIMO solutions for realizing green, secure and high data throughput wireless communications. The novelty of this project is four-fold. Firstly the project brings together two advanced MIMO - technologies, massive MIMO and cloud radio access networks (C-RAN), where a novel heterogeneous network architecture is proposed to boost network capacity by effectively exploiting the advantages of massive MIMO and C-RAN. Secondly a rigorous - algorithm-theoretic framework for maximizing energy efficiency is developed for the proposed heterogeneous architecture, where energy harvesting is realized by applying the novel concept, simultaneous wireless information and power transfer (SWIPT). - Thirdly dynamic physical layer conditions in wireless environments are used to develop comprehensive security solutions for implementing keyless secure transmissions as well as key establishment, which will bridge the gap between physical layer - security and the conventional cryptography. Finally we will extend the existing wireless network testbed available at the consortium and carry out experimental evaluations for closing the gap between theory and practice. - - 2020-01-31, ongoing project - - - 2016-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - United Kingdom - - - ATOM - - - H2020-MSCA-RISE-2015 - - - 690750 - - - - - UNIVERSITEIT VAN AMSTERDAM - - - EUR 174 864,60 - - - Politics isn’t cool, it’s hot! Do emotions influence political attitudes? - - - EUR 174 864,60 - - - Netherlands - - - Higher or Secondary Education Establishments - - Europeans and Americans are anxious about the number of refugees entering their country; angry about unresponsive political elites; or sad how immigrants are treated. To answer the question whether these emotions influence - citizens’ political attitudes, the state-of-the-art relies primarily upon self-reported emotions. Yet, when asked to self-report emotions, people are likely to mix their initial emotion with their cognitive evaluation which leads to an invalid - measure of the emotion. In HotPolitics, I employ a ground-breaking methodological design by not relying upon self-reported emotions but measuring emotions via the actual physiological responses that citizens experience. Physiological responses are - automatic, directed by the autonomous nervous system, when the brain experiences emotion. - - - 2019-09-03, ongoing project - - - 2017-09-04 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Netherlands - - - HotPolitics - - - H2020-MSCA-IF-2016 - - - 750443 - - - - - INSTITUTE OF DEVELOPMENT STUDIES - - - EUR 195 454,80 - - - Fighting Over Land: Theory and Empirical Evidence from Colombia - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - This proposal aims to develop a research agenda on the long-term effect on civil conflict on institutions, particularly on land tenure structure. I start by building a theoretical model to establish the mechanisms and - incentives through which actors involved in an armed conflict may be interested on fighting over the control and property rights of rural land. The resulting theoretical hypotheses will be tested using a truly unique, plot-level census data set that - I digitised from Official Archives of the province of Antioquia, a Colombian region highly exposed to violence over the last fifty years. This dataset contains plot-level census data collected in 1950-55 for tax purposes. Additionally, I utilise - similar plot-level census data for 1995 and 2000. These historical data sets can be easily matched to current cadastral information, available from 2006 onward. Hence, I will have comparable plot-level census datasets from Antioquia for four - different periods, which coincide with the main shift of the intensity and expansion of the Colombian conflict. The exogenous nature of the different episodes of the conflict will provide the spatial and temporal variation to identify the effect of - violence on land tenure. Several concerns might arise about the potential non-randomness of violence. While I cannot entirely resolve these (i.e. war is not random), I propose different strategies to test the robustness of my results. The - contribution of this proposal is twofold. First, this proposal will contribute to the literature on land related conflict and the social consequences of conflict. Second, I provide technical support to many land restitution policies launched in - post-conflict settings. - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - FOL - - - H2020-MSCA-IF-2015 - - - 708448 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - CSC-TIETEEN TIETOTEKNIIKAN KESKUS OY - TRUST-IT SERVICES LIMITED - CONSIGLIO NAZIONALE DELLE RICERCHE - ATHINA-EREVNITIKO KENTRO KAINOTOMIAS STIS TECHNOLOGIES TIS PLIROFOFORIAS, TON EPIKOLNONION KAI TIS GNOSIS - SCIENCE AND TECHNOLOGY FACILITIES COUNCIL - ASSOCIATION OF COMMONWEALTH UNIVERSITIES - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - ROYAL IRISH ACADEMY - BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION - CAP DIGITAL - NATIONAL LIBRARY OF IRELAND - - - EUR 3 999 187,50 - - - Research Data Alliance - Europe 3 - - - EUR 3 999 187,50 - - - Germany - Finland - United Kingdom - Italy - Greece - United Kingdom - United Kingdom - France - Ireland - Spain - France - Ireland - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Research Organisations - Research Organisations - Other - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - The Research Data Alliance (RDA) is rapidly building the social and technical bridges that enable open sharing and re-use of data on a global level. RDA/Europe - the European plug-in to the global Research Data Alliance - activities – will ensure that European research, industrial, e-infrastructure and policy stakeholders are all aware of its achievements, engaged with and actively involved in the global RDA activities and will advance the use of its results. European - domain scientists and data scientists are involved in and driving a series of working and interest groups, generating first results of RDA and this momentum should be maintained and even increased. A collaborative web platform, currently under strong - development, is widely used by the RDA members and coordinating administration. RDA Europe will look for innovative ways of facilitating the take-up and implementation of RDA outputs in Europe, both in academia and industry, and will continue to - develop and maintain the RDA web-based collaboration framework. Further steps will be taken in steering, planning and implementing the sustainability of RDA through a legal entity, established in Europe, and investigating the most appropriate - business models for long term sustainability. This RDA/Europe proposal will mainly build on the successful consortium of the previous years but strengthen its anchoring at policy, scientific and industrial uptake to drive forward RDA Europe - objectives that are all grounded in technological excellence and innovation and have clear international ties. RDA Europe partners are very actively involved in the strategic planning, implementation, marketing & communication of RDA through the - governance bodies of RDA. - - 2018-02-28, ongoing project | - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.3."> - - - EINFRA-3-2014 - Towards global data e-infrastructures – Research Data Alliance - - - CSA - Coordination and support action - - - Germany - - - RDA Europe - - - H2020-EINFRA-2014-2 - - - 653194 - - - - - THE HEBREW UNIVERSITY OF JERUSALEM - - - EUR 278 674,20 - - - Behavior-dependent interactions between frontal and somatosensory cortices - - - EUR 278 674,20 - - - Israel - - - Higher or Secondary Education Establishments - - The mammalian brain integrates behaviorally relevant sensory information by recruiting large parts of the neocortex to enable precise perception, apt decisions and adequate actions. The large-scale interactions and the - distinct roles of the various neocortical regions, namely frontal motor-related areas and posterior sensory-related regions, remain poorly understood. Here, we aim to characterize how behavior-related activity in higher-order regions (e.g. frontal - area) of the mouse is spatiotemporally organized, and how does it relate to lower-order regions (e.g. somatosensory cortex). Mice will be trained on an S1-dependent texture discrimination task under head-fixed conditions, enabling simultaneous - imaging of neuronal populations. First, we will use a novel wide-field preparation to map lower and higher-order functions throughout the cortex. Next, we will zoom-in on specific areas of interest using two-photon microscopy to achieve single cell - resolution. Finally, we will use an array of labeling techniques to track behavior-dependent activity of neuronal populations that project to a specific area. A special emphasis will be to identify how the activity in subsets of neurons that project - ‘top-down’, from frontal areas to the primary sensory area, relates to different behavioral aspects. We expect that our results will provide fundamental insights into the contribution of frontal cortical regions to perception-related and - decision-related activity before sensation (anticipation), during sensation (texture touch) and after sensation (holding in memory and 'licking for reward' action). We believe that this multidisciplinary project in behaving animals is a challenging - and promising approach bound to generate novel and exciting results which will be of great interest to the scientific community. - - 2019-07-31, ongoing project - - - 2016-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Israel - - - AG-GF - - - H2020-MSCA-IF-2014 - - - 659719 - - - - - Klinikum der Universitaet Regensburg - THE UNIVERSITY OF NOTTINGHAM - ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI - KAROLINSKA INSTITUTET - FUNDACION PARA LA INVESTIGACION BIOSANITARIA DE ANDALUCIA ORIENTAL-ALEJANDRO OTERO - UNIVERSITAET ULM - ACADEMISCH ZIEKENHUIS GRONINGEN - UNIVERSITEIT MAASTRICHT - UNIVERSITAT ZURICH - PARIS-LODRON-UNIVERSITAT SALZBURG - UNIVERSYTET MEDYCZNY W LODZI. - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 3 823 896,60 - - - European School for Interdisciplinary Tinnitus Research - - - EUR 3 823 896,60 - - - Germany - United Kingdom - Italy - Sweden - Spain - Germany - Netherlands - Netherlands - Switzerland - Austria - Poland - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - The European School for interdisciplinary tinnitus research (ESIT) provides an opportunity for young researchers to work on leading-edge research projects, which will radically improve the situation of 42 million European - tinnitus patients. They will develop new treatment solutions for tinnitus, fundamentally improve existing treatment paradigms, implement innovative research methods, perform the first genetic studies on tinnitus and establish the largest pan-European - tinnitus dataset, which will allow the implementation of innovative solutions for personalized tinnitus treatment. High quality network-wide training will prepare the individual researchers with outstanding academic as well as personal skills to - perform these tasks. - - - 2021-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - ESIT - - - H2020-MSCA-ITN-2016 - - - 722046 - - - - - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - - - EUR 173 076 - - - Synapse formation and maturity through planar cell polarity pathway - - - EUR 173 076 - - - France - - - Research Organisations - - SynPCP is a MSCA-IF-EF project in Neuroscience aimed at deciphering spatiotemporal mechanisms controlled by the planar cell polarity (PCP) protein Scribble (Scrib) in spine during specification and morpho-fonctional plasticity - that depend on the dynamics of the actin cytoskeleton and trans-synaptic adhesions. Growing evidences suggest that PCP signaling is fundamental for neuronal development mechanisms, including dendrite morphogenesis and synaptogenesis. PCP signaling - defects have been linked to a number of human neuropathies such as autism. Because of its subcellular compartment localization and interaction with actin, we hypothesize that Scrib nanoscale organization within the spine could control cytoskeleton - and/or adhesion dynamics. To address this, I plan to study the coupling or interplay between Scrib-dependent signaling and the assembly of actin cytoskeleton macromolecular complexes and its connection to cadherin-adhesion molecules using - biochemistry, biophysics and 3D super-resolution optical microscopy techniques, in normal and pathological conditions. This project will provide novel conceptual insights into the nanoscale segregation of PCP proteins in spines and how individual PCP - proteins control the actin cytoskeleton to build functional synapses. This project will offer a multilevel and interdisciplinary approach to understand the consequences of mutations of PCP signaling at the nanoscale, cellular and physiological - levels, on the establishment, maturation and function of the basic functional unit of neuronal integration in the complex circuit of the hippocampus: the dendritic spine. SynPCP will be setup at the Bordeaux Neurocampus which is well known for its - contribution to synapse development and brain function. This project offers a scientific and training program critical for my career but also for the general understanding of the molecular mechanisms underlying the normal and pathological brain. - - 2020-02-29, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - SynPCP - - - H2020-MSCA-IF-2016 - - - 750253 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 170 121,60 - - - BEYOND THE CODE: SUSTAINABILITY IN OPEN SOURCE - - - EUR 170 121,60 - - - Spain - - - Research Organisations - - Open Source (OS) software is particular in that it can be accessed and modified openly. Originating from technological labs, OS is now ubiquitous and a major part of the EU's economy. Some estimate it to be 450 billions per - year (EUR). The increasing ubiquity of OS has turned it into a configuration of social and societal elements such as the decentralised ownership of projects or meeting needs that traditional markets cannot. The socio-technical configurations of OS - are not evident, perhaps not even intended. The various meanings of sustainability enact how OS ideas are created and travel beyond their original birthing place, but have, as yet, mainly received a rational/economic focus. This project proposes to - explore OS as it travels beyond its designing communities and, in so doing, re-functions the meaning of sociological sustainability that hold it in place. - - - 2019-09-15, ongoing project - - - 2017-09-16 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - BEYOND-CODE - - - H2020-MSCA-IF-2016 - - - 744957 - - - - - FORSCHUNGSVERBUND BERLIN EV - - - EUR 159 460,80 - - - The genomic basis of convergent evolution in modern sloths (Xenarthra, Mammalia) - - - EUR 159 460,80 - - - Germany - - - Research Organisations - - At the end of the Pleistocene mass extinctions of the mega-fauna occurred worldwide, in particular in the Americas. Following the last glacial period, mammoths, mastodonts, giant sloths and other large mammals succumbed until - extinction (about 10,000 years ago). While some Orders within Mammalia lost a couple of species, the sloths (Folivora, Xenarthra) clade has virtually lost all its diversity, gaining a status of a nearly-extinct suborder. Only two out of the close to - 100 genera estimated to have existed survived to the mass extinctions to this date, named Bradypus and Choloepus. In contrast to their giant relatives, the modern sloths are medium-sized animals that developed a very specialized feature: obligatory - arboreal suspensory behaviour. Their surprisingly high number of superficial similarities were acquired in parallel – since both genera are completely unrelated, and probably diverged ~30 Mya – and represent an amazing example of convergent - evolution. In the current Genomics era, we are finally at a point in which full genomes can be assembled for non-model organisms at reasonable costs, bringing unprecedented opportunities for new studies on elementary questions on evolution. Here we - propose to study the genomic signs of convergent evolution leading to obligatory suspensory locomotion and low metabolic rate on a comparative genomic analysis including 4 whole genome sloth sequences, three of which will be sequenced and assembled - within this study. The Experienced Researcher masters all the bioinformatics expertise to complete the genomes. The host institution offers all the infrastructure and hypothesis thinking to successfully finalize the project. Jointly this team can - push the boundaries of biological knowledge beyond, which will help the applicant to mature in order to lead a research group in the future. The applicant will also be trained in project management, supervision, teaching, and presentation of - scientific results. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - CONVGENOMS - - - H2020-MSCA-IF-2016 - - - 750747 - - - - - UNIVERSITY OF LEEDS - - - EUR 195 454,80 - - - Shear Stress Induced Arterial and Venous Specification through Piezo1 - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Arteriovenous malformations (AVMs) are characterised by abnormal connections between arteries and veins due to defects during vascular remodelling. Although often asymptomatic, AVMs can cause intense pain and patients affected - present higher risk for strokes and aneurysms. Hereditary AVMs have a prevalence of 18 in 100000 people causing a two-fold increase in mortality in patients younger than 60 years of age. Hereditary AVMs are linked to defective Notch/BMP signalling, - however they represent less than 10% of cases. The majority of AVMs do not present genetic mutations and remain idiopathic. - - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SAVE - - - H2020-MSCA-IF-2016 - - - 748369 - - - - - IT-UNIVERSITETET I KOBENHAVN - - - EUR 200 194,80 - - - Infrastructuring SuStainable Playbour - - - EUR 200 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - "This proposal relates to the sustainability of grassroots, collaborative and participative socio-technical communities to the extent that it focuses on the paradigmatic case of playbour: a concept describing “a condition - where play is work and work is play“ and referring to those collaborative and participative assemblages where the dimensions of fun and enjoyment, typical of engagement in play, blur and mix with the ones of productivity and professionalization of - participation. Overarching goal of this proposal is to develop a set of guidelines and principles which would support practitioners and scholars in nurturing collaborative infrastructures that embed sustainability by (co)design. The research relies - on the analytical lens of infrastructure and infrastructural inversion typical of Science and Technology Studies (STS). At the empirical level the research involves a comparative case study approach which will examine socio-technical collectives - which are engaged in playbour and are in the maturity stage of their life cycle. Qualitative data gathering (participant observation and interviewing) and inductive analysis techniques (grounded theory) will be adopted for this study. The impact of - this study will be relevant to the extent that European Commission is also trying to nurture and steer collaborative, grassroots and innovative initiatives (e.g. ""Open and Participative Innovation"" and ""Collective Awareness Platform for - Sustainability and Social Innovation” frames). The result of this research will also provide practical insights for the sustainability of these instances." - - 2020-01-07, ongoing project - - - 2018-01-08 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - ISSP - - - H2020-MSCA-IF-2016 - - - 749353 - - - - - FREIE UNIVERSITAET BERLIN - FREIE UNIVERSITAET BERLIN - - - EUR 2 435 113 - - - The Arabic Anonymous in a World Classic - - - EUR 2 435 113,77 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - AnonymClassic is the first ever comprehensive study of Kalila and Dimna (a book of wisdom in fable form), a text of premodern world literature. Its spread is comparable to that of the Bible, except that it passed from Hinduism - and Buddhism via Islam to Christianity. Its Arabic version, produced in the 8th century, when this was the lingua franca of the Near East, became the source of all further translations up to the 19th century. The work’s multilingual history involving - circa forty languages has never been systematically studied. The absence of available research has made world literature ignore it, while scholars of Arabic avoided it because of its widely diverging manuscripts, so that the actual shape of the - Arabic key version is still in need of investigation. AnonymClassic tests a number of ‘high-risk’ propositions, including three key hypotheses: 1) The anonymous Arabic copyists of Kalila and Dimna are de facto co-authors, 2) their agency is - comparable to that of the named medieval translators, and 3) the fluctuation of the Arabic versions is conditioned by the work’s fictional status. AnonymClassic’s methodology relies on a cross-lingual narratological analysis of the Arabic versions - and all medieval translations (supported by a synoptic digital edition), which takes precisely the interventions at each stage of transmission (redaction, translation) as its subject. Considering the work’s paths of dissemination from India to - Europe, AnonymClassic will challenge the prevalent Western theoretical lens on world literature conceived ‘from above’ with the view ‘from below,’ based on the attested cross-cultural network constituted by its versions. AnonymClassic will introduce - a new paradigm of an East-Western literary continuum with Arabic as a cultural bridge. Against the current background of Europe’s diversifying and multicultural society, AnonymClassic purposes to integrate pre-modern Near Eastern literature and - culture into our understanding of Global Culture. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - AnonymClassic - - - ERC-2016-ADG - - - 742635 - - - - - TECHNISCHE UNIVERSITAET DRESDEN - TECHNISCHE UNIVERSITAET DRESDEN - - - EUR 150 000 - - - Scalable and efficient production of functionalized, high-performance solution-processable graphene-materials - - - EUR 150 000 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The worldwide increasing need for resources and energy as well as the foreseeable depletion of fossil fuels has led scientists into a race towards finding cleaner, more efficient and sustainable technologies. Graphene is - believed to be able to play a crucial role in these developments due to its outstanding properties like excellent conductivity, mechanical strength, flexibility and chemical stability. A possible large-scale application is foreseen in polymer - composites, where next to increased mechanical stability, graphene can introduce additional functionalities such as conductivity, antistatic properties or flame retardancy to specialty and commodity polymers. In addition, the potential to integrate - cheap graphene-based, printed sensors, actuators, or networking capabilities into every-day products opens up completely new fields of application (e.g. the Internet of Things vision). Current industrial preparation techniques are available to - provide graphene at large scale but the materials suffer from drawbacks in terms of processability, which is why despite the great potential, only a very limited number of graphene-enhanced products are available on the market. Recently, we were able - to demonstrate a novel technology for the functionalization of graphene. With this approach, we are now focusing to produce functionalized graphene with tailorable properties and improved processability. This breakthrough will open up new - possibilities and prospects for the application of graphene. To exploit the potential impact of this approach we are aiming to prove the usability of our functionalized graphene in different applications in cooperation with experienced partners from - industry. - - 2019-02-28, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Germany - - - HIPER-G - - - ERC-2017-PoC - - - 768930 - - - - - UNIVERSITA DEGLI STUDI DI VERONA - UNIVERSITA DEGLI STUDI DI VERONA - - - EUR 2 750 000 - - - Autonomous Robotic Surgery - - - EUR 2 750 000 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The goal of the ARS project is the derivation of a unified framework for the autonomous execution of robotic tasks in challenging environments in which accurate performance and safety are of paramount importance. We have - chosen surgery as the research scenario because of its importance, its intrinsic challenges, and the presence of three factors that make this project feasible and timely. In fact, we have recently concluded the I-SUR project demonstrating the - feasibility of autonomous surgical actions, we have access to the first big data made available to researchers of clinical robotic surgeries, and we will be able to demonstrate the project results on the high performance surgical robot “da Vinci - Research Kit”. The impact of autonomous robots on the workforce is a current subject of discussion, but surgical autonomy will be welcome by the medical personnel, e.g. to carry out simple intervention steps, react faster to unexpected events, or - monitor the insurgence of fatigue. The framework for autonomous robotic surgery will include five main research objectives. The first will address the analysis of robotic surgery data set to extract action and knowledge models of the intervention. - The second objective will focus on planning, which will consist of instantiating the intervention models to a patient specific anatomy. The third objective will address the design of the hybrid controllers for the discrete and continuous parts of the - intervention. The fourth research objective will focus on real time reasoning to assess the intervention state and the overall surgical situation. Finally, the last research objective will address the verification, validation and benchmark of the - autonomous surgical robotic capabilities. The research results to be achieved by ARS will contribute to paving the way towards enhancing autonomy and operational capabilities of service robots, with the ambitious goal of bridging the gap between - robotic and human task execution capability. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Italy - - - ARS - - - ERC-2016-ADG - - - 742671 - - - - - THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN - THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN - - - EUR 1 999 998 - - - From Typhoid Fever to Antimicrobial Mechanisms - - - EUR 1 999 998 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This programme will identify critical host mechanisms that kill bacterial pathogens by exploring a novel mammalian antimicrobial pathway, which I discovered. This pathway protects non-susceptible hosts from typhoid fever. - Typhoid fever is caused by Salmonella Typhi, a unique intracellular pathogen that kills more than 200,000 humans per year. Yet, Salmonella Typhi does not infect other mammalian species, such as mice. An understanding of the mechanisms that protect - mice from Salmonella Typhi infection will enable me to determine how Salmonella Typhi circumvents these protective mechanisms in humans to cause fatal disease. I have demonstrated that the mechanisms protecting mice are based on an intracellular - trafficking process regulated by the Rab32 GTPase. The following critical questions will be addressed: - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - TYPHI - - - ERC-2016-COG - - - 726152 - - - - - FORSCHUNGSVERBUND BERLIN EV - FORSCHUNGSVERBUND BERLIN EV - - - EUR 2 499 991 - - - Volume regulation and extracellular signalling by anion channels - - - EUR 2 499 991 - - - Germany - Germany - - - Research Organisations - Research Organisations - - Cells must regulate their volume in response to changes in osmolarity and during cell division, migration, apoptosis, and transepithelial transport. Regulated membrane transport of ions and metabolites creates osmotic - gradients that secondarily drive water across the membrane. Organic ‘osmolytes’ such as glutamate also serve in extracellular signalling and volume-regulatory ion transporters are often used for other purposes, putting volume regulation into the - context of diverse organismal functions. - - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - VOLSIGNAL - - - ERC-2016-ADG - - - 740537 - - - - - KOBENHAVNS UNIVERSITET - UNIVERSITE DES SCIENCES ET TECHNOLOGIES DE LILLE - LILLE I - UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II. - UNIVERSITY OF YORK - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - DEVRO PLC - - - EUR 2 186 974,80 - - - Teaching Emerging Methods in Palaeoproteomics for the European Research Area - - - EUR 2 186 974,80 - - - Denmark - France - Italy - United Kingdom - Germany - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - TEMPERA will provide international, intersectoral and interdisciplinary state-of-the-art doctoral training to prepare the next generation of specialists in mass spectrometry-based ancient protein residues analysis for - biomolecular diagnostics and conservation of cultural heritage material. - - 2021-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Denmark - - - TEMPERA - - - H2020-MSCA-ITN-2016 - - - 722606 - - - - - UNIVERSITE DE FRIBOURG - UNIVERSITE DE FRIBOURG - - - EUR 2 495 930 - - - Locus Ludi: The Cultural Fabric of Play and Games in Classical Antiquity - - - EUR 2 495 930 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Play and games were ubiquitous in antiquity, among free men and slaves, men and women, adults and children, in town and country. Even gods played. Ludic culture created communities from early childhood to a ripe old age. Did - these groups play together, or did they play different games, with distinct rules? And did they play similar games to us? This interdisciplinary project will provide the first comprehensive study of the evidence. Written, archaeological and - iconographic sources are abundant, but forgotten in museums and libraries. This neglect is due to the modern Western view of games as children’s pastime, if not a waste of time. Ancient play and games reflect the gendered, religious, economic, and - political fabric of a society, as much as they shape the lives of players by transmitting a cultural identity and an intangible heritage. Ludic culture evolves over time and this project intends to provide a benchmark by reconstructing this history - in the Greek world, from the birth of the city-state, c. 800 BCE, to the Roman conquest in 146 BCE, and in the Roman world from the Republican age, c. 500 BCE, to the end of the Western Roman Empire, c. 500 CE. - - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Switzerland - - - Locus Ludi - - - ERC-2016-ADG - - - 741520 - - - - - Eidgenössische Technische Hochschule Zürich - Eidgenössische Technische Hochschule Zürich - - - EUR 2 500 000 - - - In Vivo Single-Cell Mechanomics of Bone Adaptation and Regeneration in the Aging Mouse - - - EUR 2 500 000 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Osteoporosis, one of the most prevalent degenerative diseases, is characterized by a reduction in bone mass and increased fracture risk and has been partly attributed to the decrease in mechanical usage of the skeleton. A - detailed understanding of the molecular mechanisms governing load-regulated bone remodeling could therefore lead to the identification of molecular targets for the development of novel therapies. Bone remodeling is a multiscale process mediated - through complex interactions between multiple cell types and their local 3D environments. However, the underlying mechanisms of how cells respond to mechanical signals are still unclear. By combining single-cell “omics” technologies with - well-established tissue-scale models of bone mechanobiology, MechAGE proposes to develop the technology required to allow spatially resolved in vivo single-cell mechanomics of bone adaptation and regeneration. CRISPR/Cas technology will be exploited - to generate fluorescent reporter mice to identify the different cell types involved in the bone remodeling process. By combining RNA-sequencing of single cells isolated by laser-capture microdissection with micro-finite element analysis and - time-lapsed in vivo micro-CT, MechAGE will link the transcriptome of hundreds of single cells to their local mechanical in vivo environment (LivE). This will allow investigation of molecular responses of the cells to LivE changes with aging in - established mouse models of bone adaptation and regeneration. In addition to in vivo mechanomics, MechAGE proposes to use cellular and multiscale computational modeling to run in silico simulations of real-world events for better understanding of - diseases of aging in mice and to maximize the use of the high quality in vivo mechanomic data. Findings from MechAGE will lead to a systems level understanding of the spatio-temporal regulation of gene expression during the process of load-induced - bone adaptation and regeneration in the aging mouse. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Switzerland - - - MechAGE - - - ERC-2016-ADG - - - 741883 - - - - - STICHTING WAGENINGEN RESEARCH - THE QUEEN'S UNIVERSITY OF BELFAST - VYSOKA SKOLA CHEMICKO-TECHNOLOGICKA V PRAZE - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - LINKOPINGS UNIVERSITET - AQUAMARIJN MICRO FILTRATION BV - CSEM CENTRE SUISSE D'ELECTRONIQUE ET DE MICROTECHNIQUE SA - RECHERCHE ET DEVELOPPEMENT - - - EUR 2 843 040,96 - - - Smartphone analyzers for on-site testing of food quality and safety - - - EUR 2 843 040,96 - - - Netherlands - United Kingdom - Czech Republic - Spain - Sweden - Netherlands - Switzerland - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - - Current food quality and safety testing is, to a large extent, an inefficient, expensive and ineffective process, unable to assure food safety for all consumers and unable to prevent major food fraud incidents. A paradigm - shift in quality and safety testing is urgently required in order to free resources for an intensified combat against fraud in the food chain. As an enabling technology solution, the FoodSmartphone ETN proposes the development of smartphone-based - (bio)analytical sensing and diagnostics tools for simplified on-site rapid pre-screening of food quality and safety parameters and wireless data transfer to servers of relevant stakeholders. FoodSmartphone comprises 7 Training Sites (3 universities, - 3 research centres, 1 innovation SME), plus 2 Partner Organisations (1 global food industry and 1 diagnostics SME). The consortium has been built upon highly complementary disciplines: (bio)analytical chemists, biologists, physicists, - micro-engineers, mathematicians and food chemists will work together on the joint supra-disciplinary goal. FoodSmartphone provides a unique mix of exciting local PhD research covering all aspects of smartphone-based screening tools plus a wealth of - network-wide science & innovation and transferable skills training: the ETN provides more than 14 network-wide and transferable skills training events and 16 optional- and 11 mandatory intersectoral secondment opportunities. The ETN and results - thereof will be widely disseminated to key stakeholders, embedded in continuous education programs and translated into a final exploitation plan. Scientific awareness of the next generation and public engagement will be boosted by several - well-targeted outreach activities. The scientific training in novel smartphone-based sensing technologies plus the complementary skills training provided will have a major impact on future EU monitoring practices and, moreover, pave the road for - Citizen Science approaches to food quality and safety testing. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Netherlands - - - FoodSmartphone - - - H2020-MSCA-ITN-2016 - - - 720325 - - - - - KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW - INSTITUT NATIONAL D'ETUDES DEMOGRAPHIQUES - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - HUNGARIAN CENTRAL STATISTICAL OFFICE DEMOGRAPHIC RESEARCH INSTITUTE - SZKOLA GLOWNA HANDLOWA W WARSZAWIE - UNIVERSITEIT UTRECHT - BUNDESINSTITUT FUR BEVOLKERUNGSFORSCHUNG - UNIVERSITA COMMERCIALE LUIGI BOCCONI - - - EUR 1 996 667,50 - - - Generations and Gender Programme: Evaluate, Plan, Initiate - - - EUR 1 996 667,50 - - - Netherlands - France - Germany - Hungary - Poland - Netherlands - Germany - Italy - - - Research Organisations - Research Organisations - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - - The Generations and Gender Programme (GGP) provides high quality cross-national, longitudinal data for the study of population change. The data provided by the GGP have been used by more than 3,000 researchers worldwide and - have led to over 500 peer-reviewed journal articles. The data have provided insights into some of the most pressing societal challenges such as care for older persons, female employment, inequality, social exclusion, social mobility and migration. - The overall objective of GGP-EPI is to bring the GGP to the level of maturity required for inclusion as an active project on the 2020 ESFRI Roadmap and eventually for its full implementation as a distributed research infrastructure. Specifically, the - project sets out to ‘Evaluate, Plan and Initiate’ the GGP’s transition to a distributed research infrastructure through a series of activities which will strengthen all aspects of the project from its fieldwork operations through to its long term - financing and governance. This includes: (1) To evaluate the GGP’s governance and management structure and to identify the governance, financial, and legal model that will best serve the GGP and its various stakeholders; (2) To plan for the recent - and foreseeable technological and data developments and identify the e-needs of the GGP; and (3) To initiate the centralization of the GGP’s operations throughout its data life cycle and especially in connection with new data collection. In doing so, - the GGP will strengthen its position in the European Research Area, and will deliver innovative, cutting edge data on population change for researchers and policy makers. - - 2019-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-02-2016 - Preparatory Phase and support to early phase of ESFRI projects - - - RIA - Research and Innovation action - - - Netherlands - - - GGP-EPI - - - H2020-INFRADEV-2016-2 - - - 739511 - - - - - Eidgenössische Technische Hochschule Zürich - CARLSBERG AS - DEUTSCHE SAATVEREDELUNG AG - BASECLEAR BV - AGROISOLAB GMBH - HELIOSPECTRA AB - LEMNATEC GMBH - NPZ INNOVATION GMBH - UNIVERSITAT ZURICH - UNIVERSITAET BASEL - - - EUR 2 617 989,18 - - - PlantHUB - Boosting technology transfer and responsible research and innovation (RRI) in plant sciences - - - EUR 2 617 989,18 - - - Switzerland - Denmark - Germany - Netherlands - Germany - Sweden - Germany - Germany - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In PlantHUB will capture the academic, industrial and regulatory expertise from 5 world-class universities, 1 public research organisation, 1 governmental organization, 8 enterprises including 5 SMEs to train 10 ESRs in skills - and competencies necessary to apply responsible research and innovation (RRI) in the area of plant breeding and production. We wish to address the demand of RRI leadership in plant science related research and diffusion of innovation. The individual - research projects are demand-driven, responding to the needs of companies - particular SMEs - to increase R&I capacities. The outcomes are new molecular tools for plant breeding, new forage, cereal and oil crop varieties, non-invasive imaging and - phenotyping technologies, intelligent lighting systems for plant growth, new software and services for complex genomic analyses, and plant product quality. PlantHUB industrial doctoral programme is ground-breaking in a number of respects: (i) - doctoral training is placed into an entrepreneurial environment of leading public and private organisations (ii) it combines practical hands-on R&D and technology transfer in plant breeding and production with RRI training and practise. On - completion of the training, graduates will have deep interdisciplinary knowledge of plant breeding, crop improvement, high-throughput technologies, isotope and big data analysis. In combination with a portfolio of transferable skills they will be - able to take a lead in stakeholder & public engagement, innovation management, technology transfer and entrepreneurship. Our programme will become a flagship example at the forefront of intersectoral research, underpinned with a carefully created - training curriculum to foster awareness, know-how, expertise and competence in RRI. - - 2020-11-30, ongoing project - - - 2016-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-EID - European Industrial Doctorates - - - Switzerland - - - PlantHUB - - - H2020-MSCA-ITN-2016 - - - 722338 - - - - - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - KOBENHAVNS UNIVERSITET - UNIVERSITA DEGLI STUDI DI CAMERINO - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - IBM RESEARCH GMBH - STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN - UNIVERSITA TA MALTA - AALTO-KORKEAKOULUSAATIO - UNIVERSITAT KONSTANZ - UNIVERSITEIT GENT - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - THALES SA - TECHNISCHE UNIVERSITEIT DELFT - Institute of Science and Technology Austria - HITACHI EUROPE LIMITED - STMICROELECTRONICS SRL - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 10 000 000 - - - Hybrid Optomechanical Technologies - - - EUR 10 000 000 - - - Switzerland - Denmark - Italy - United Kingdom - Switzerland - Netherlands - Malta - Finland - Germany - Belgium - France - France - Netherlands - Austria - United Kingdom - Italy - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - The hybrid optomechanical technologies (HOT) consortium will lay the foundation for a new generation of devices, which connect, or indeed contain, several platforms at the nanoscale in a single “hybrid” system. As hybrid - interfaces they will allow to harness the unique advantages of each subsystem within a nano-scale footprint, while as integrated hybrid devices they will enable entirely novel functionalities. A particular focus will be on nano-optomechanical devices - that comprise electrical, microwave or optical systems with micro- and nano-mechanical systems. Research in the past decade, in particular by European groups, has shown the significant technological potential that such nano-optomechanical systems can - offer, in particular by establishing a new way in which optical, radio-frequency and microwave signals can be interfaced. The present consortium includes leading academic groups and industrial partners to explore the potential of these - hybrid-nano-optomechanical systems. It will explore hybrid opto- and electro-mechanical devices operating at the physical limit for conversion, synthesis, processing, sensing and measurement of EM fields, comprising radio, microwave frequencies to - the terahertz domain. These spectral domains open realistic applications in the existing application domains of medical (e.g. MRI imaging), security (e.g. Radar and THz monitoring), positioning, timing and navigations (Oscillators) and for future - quantum technology. The research aims at specific technological application, with realistic operating conditions and seeks to develop actual system demonstrators. In addition, it will explore how these hybrid transducers can be fabricated within - standard CMOS processing, and thereby be made compatible with current manufacturing methods. The HOT devices will thereby impact today’s technology and likewise address potential future need for the manipulation of quantum signals. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.2."> - - - FETPROACT-01-2016 - FET Proactive: emerging themes and communities - - - RIA - Research and Innovation action - - - Switzerland - - - HOT - - - FETPROACT-2016 - - - 732894 - - - - - SYDDANSK UNIVERSITET - SYDDANSK UNIVERSITET - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 344 497,50 - - - Transgenerational regulation of glucose metabolism by noncoding RNAs - - - EUR 1 344 497,50 - - - Denmark - Denmark - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Obesity and T2D affect large populations and cause a decline in life expectancy if untreated. The pandemic proportion of obesity and inaptitude of anti-obesity approaches reflect our limited understanding of its complex - environmental and genetic etiology. Genome-wide association studies revealed that disease-associated risk variants are often situated in those 98% of the genome not encoding for proteins. This noncoding genomic space yet does not reflect ‘Junk DNA’ - but gives rise to >10,000 noncoding RNAs like microRNAs and long, noncoding RNAs (lncRNAs) that implicated in control of glucose metabolism and energy homeostasis also by the applicant (Kornfeld et al. Nature 2013). - - - 2021-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Denmark - - - TransGen RNA - - - ERC-2015-STG - - - 675014 - - - - - UNIVERSITE DU MANS - UNIVERSITE DE NANTES - CARDIFF UNIVERSITY - PANEPISTIMIO KRITIS - UNIWERSYTET SZCZECINSKI - KOBENHAVNS UNIVERSITET - FUNDACION CANARIA PARQUE CIENTIFICO TECNOLOGICO DE LA UNIVERSIDAD DE LAS PALMAS DE GRAN CANARIA - ZURCHER HOCHSCHULE FUR ANGEWANDTE WISSENSCHAFTEN - MICROPHYT - INSTITUTO TECNOLOGICO DE CANARIAS, S.A. - INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER - UNIVERSITE D ORAN - UNIVERSITAS BRAWIDJAJA - UNIVERSITAS PAJAJARAN - TRUONG DAI HOC SAI GON - UNIVERSITAS TANJUNGPURA - UNIVERSITE LAVAL - UNIVERSITE DU QUEBEC A RIMOUSKI - MOUNT ALLISON UNIVERSITY - MIDDLE TENNESSEE STATE UNIVERSITY - THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK - UNIVERSITY OF TASMANIA - - - EUR 1 602 000 - - - The Genus Haslea, New marine resources for blue biotechnology and Aquaculture - - - EUR 1 602 000 - - - France - France - United Kingdom - Greece - Poland - Denmark - Spain - Switzerland - France - Spain - France - Algeria - Indonesia - Indonesia - Vietnam - Indonesia - Canada - Canada - Canada - United States - United States - Australia - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - Higher or Secondary Education Establishments - - The GHaNA project aims to explore and characterize a new marine bioresource, for blue biotechnology applications in aquaculture, cosmetics and possibly food and health industry. The project will determine the biological and - chemical diversity of Haslea diatoms to develop mass-scale production for viable industrial applications by maximising biomass production and associated high-value compound production, including terpenoids, marennine-like pigments, lipids and silica - skeletons. The genus Haslea species type H. ostrearia, produces marennine, a water-soluble blue pigment used for greening oysters in Western France, which is also a bioactive molecule. Haslea diatoms have thus a high potential for use in (1) existing - oyster farming, (2) production of pigments and bioactive compounds with natural antibacterial properties, (3) application as a colouring agent within industry, and (4) use of silica skeletons as inorganic “biocharges” in the formulation of new - elastomeric materials. This will be achieved through fundamental and applied-oriented research to isolate fast- growing strains of Haslea, optimising their growth environment to increase marennine and other high-value compound productivity; to - develop blue biotechnology specifically applied to benthic microalgae (biorefinery approach, processes); and to develop industrial exploitation of colouring and bioactive compounds through commercial activities of aquaculture, food, cosmetics and - health. - - 2021-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - France - - - GHaNA - - - H2020-MSCA-RISE-2016 - - - 734708 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - - - EUR 257 860,80 - - - Fuse smFRET and modeling to a new structural biology method and solve the functional ESCRT assembly structure - - - EUR 257 860,80 - - - Germany - United States - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Higher or Secondary Education Establishments - - We seek to develop a new structural biology method that is able to overcome barriers to solving very complex functional protein assemblies that are variable enough in their composition and conformation to defeat current methodologies. - - - 2018-12-31, Grant Agreement terminated - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Germany - - - smSTRUCT - - - H2020-MSCA-IF-2014 - - - 659446 - - - - - UNIVERSITAT ZURICH - UNIVERSITAT ZURICH - UNIVERSITAET BASEL - - - EUR 1 499 925 - - - Spin-Delocalization with a Twist: Chiral Open-Shell Helices - - - EUR 1 499 925 - - - Switzerland - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Spin-delocalization in molecules containing unpaired electrons gives rise to an unusual intermolecular interaction, named as pancake bond. This bonding interaction couples unpaired electrons between multiple pairs of atoms - from each face-to-face oriented spin units, such as phenalenyl radical, and abets formation of assemblies that display large antiferromagnetic interaction in the solid state. This phenomenon governs the potential use of such spin systems as molecular - conductors, magneto-optical bistable materials, or molecular spin batteries. Formation of such assemblies during crystallization is spontaneous. It is therefore difficult to control and tune the antiferromagnetic interaction, which dictates the - electronic properties of the solid material. Inspired by this challenge, the goal of this project is to develop systems, where the spin-interaction can be tuned within a single molecule to understand principles that govern an intermolecular assembly - in the solid state and the bulk properties. - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Switzerland - - - INSPIRAL - - - ERC-2016-STG - - - 716139 - - - - - UNIVERSITAT ZURICH - UNIVERSITAT ZURICH - - - EUR 2 124 965 - - - Control and measurement of single macromolecules in space and time - - - EUR 2 124 965 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The desire to “freely suspend the constituents of matter” in order to study their behaviour can be traced back over 200 years to Lichtenberg’s diaries. From radio-frequency ion traps to optical tweezing of colloidal particles, - existing methods to trap matter in free space or solution rely on the use of external fields that often strongly perturb the integrity of a macromolecule in solution. Recently, I invented the ‘electrostatic fluidic trap’, a “field-free” principle - that supports stable, non-destructive confinement of single macromolecules in room temperature fluids, representing a paradigm shift in a nearly century-old field. The spatio-temporal dynamics of a single electrostatically trapped molecule reveals - fundamental information on its properties, e.g., size and electrical charge. The charge of a macromolecule is in turn a strong function of its 3D conformation - the molecular basis of biological function. I now aim to develop a new platform to study - 3D macromolecular structure and temporal conformation by measuring the electrical charge of a single trapped molecule in real time, using both optical microscopy and electrical detection. Beyond the conformational dynamics of a single molecule, we - will also examine interactions between two or more molecules, and the detection of minute structural differences between closely related molecular isoforms. We will further develop a novel approach to electrical transport measurements on single - molecules aimed at generating for the first time a catalog of ‘electrical signatures’ for biomolecules in solution. The ability to experimentally link electrical charge and molecular structure will not only open up a new physical dimension in our - understanding of macromolecules, but also advance the development of ultrasensitive, high-throughput molecular sensors for biomedical detection and analytics, potentially enabling an optical or electrical “single-snapshot” read-out of the proteome or - transcriptome of a single cell. - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Switzerland - - - COSMOS - - - ERC-2016-COG - - - 724180 - - - - - KOBENHAVNS UNIVERSITET - KOBENHAVNS UNIVERSITET - - - EUR 1 339 600 - - - Hybrid Epitaxial Materials for Novel Quantum State Detection and Manipulation - - - EUR 1 339 600 - - - Denmark - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Research in quantum information technologies is receiving increasing attention worldwide, and huge efforts are put into the realization of the first reliable building blocks for quantum computation. The main challenge the - field is facing today is unquestionably related to the loss of information due to quantum state decoherence. As indicated by our recent experiments, the perennial problem of decoherence might be solved by fully epitaxial semiconductor-superconductor - growth techniques of high quality topological superconducting materials. Moreover, quantum systems based around design principles such as gate-controlled semiconductor-superconductor materials that can hold topologically‐motivated symmetry - protection, might enable simpler forms of control and less dependence on available control technology. - - 2022-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Denmark - - - HEMs-DAM - - - ERC-2016-STG - - - 716655 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 499 923 - - - Genetic Mapping of Evolutionary Developmental Variation using Hybrid Mouse in vitro Crosses - - - EUR 1 499 923 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Discovering the genetic changes underlying species differences is a central goal in evolutionary genetics. Most evolutionarily important traits affecting fitness are complex or quantitative traits, whose genetic bases are - elusive. In mammals, dissecting the genetic basis of complex trait variation is particularly challenging, because efficient genetic mapping requires enormous pedigrees or specialized genetic panels that are typically beyond the resources of - individual groups. Using a radically novel method to circumvent breeding limitations by “breeding” mice in vitro, I propose to dissect the genetic basis of evolutionary developmental variation. This ground-breaking approach will allow me to create - large genetic mapping panels of potentially any size from mouse interspecific hybrids of increasing evolutionary divergence. In vitro crosses promise a breakthrough in evolutionary biology: by bypassing hybrid sterility and inviability, we will ask - which genetic changes underlie species differences. The proposed experiments address how genetic changes accumulate during evolution of new species to shape gene regulatory networks and cause phenotypic changes at the gene expression, fitness and - organismal level. This research has the potential to revolutionize genetic mapping. If realized, its impact on personalized medicine, agricultural science and evolutionary research cannot be understated. - - 2020-07-31, ongoing project - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - HybridMiX - - - ERC-2014-STG - - - 639096 - - - - - STICHTING KATHOLIEKE UNIVERSITEIT - STICHTING KATHOLIEKE UNIVERSITEIT - - - EUR 1 978 194 - - - Characterizing neural mechanisms underlying the efficiency of naturalistic human vision - - - EUR 1 978 194 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Our daily-life visual environments, such as city streets and living rooms, contain a multitude of objects. Out of this overwhelming amount of sensory information, our brains must efficiently select those objects that are - relevant for current goals, such as cars when crossing a street. The visual system has developed and evolved to optimally perform tasks like these, as reflected in the remarkable efficiency of naturalistic object detection. Little is known about the - neural mechanisms underlying this efficiency. NATVIS aims to fill this gap, presenting a comprehensive multi-method and hypothesis-driven approach to improve our understanding of the neural mechanisms underlying the efficient detection of objects in - natural scenes. fMRI, MEG, and TMS will be used to study the neural basis of rapid attentional guidance based on scene context and episodic memory, resulting in a full characterization of when, where, and how context- and memory-based expectations - interact with attentional templates in visual cortex and beyond. The powerful effects of scene context on object recognition will be studied by testing how context-disambiguated objects are represented in visual cortex, characterizing when - context-based predictions bias object processing, and testing for causal interactions between scene- and object-selective pathways in visual cortex. NATVIS will study how the brain uses real-world regularities to support object grouping and reduce - clutter in scenes, modelling the cortical representation and neural dynamics of multiple simultaneously presented objects as a function of positional regularity. Finally, advanced multivariate modelling of fMRI data will test the functional relevance - and representational content of internally generated templates that are hypothesized to facilitate object detection in scenes. This program of research tackles the next frontier in the neuroscience of high-level vision and attention, embracing the - complexity of naturalistic vision. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - NATVIS - - - ERC-2016-COG - - - 725970 - - - - - UNIVERSITE DE LIMOGES - INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON - UNIVERSITE DE VALENCIENNES ET DU HAINAUT-CAMBRESIS - FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG - BUNDESANSTALT FUER MATERIALFORSCHUNG UND -PRUEFUNG - UNIVERSITA DEGLI STUDI DI PADOVA - POLITECNICO DI TORINO - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - UNIVERSITAT POLITECNICA DE CATALUNYA - CENTRE DE RECHERCHES DE L'INDUSTRIEBELGE DE LA CERAMIQUE ASBL - 3DCERAM - SAINT-GOBAIN CENTRE DE RECHERCHES ET D'ETUDES EUROPEEN - NORAKER - ANTHOGYR SAS - ROBERT BOSCH GMBH - H.C. STARCK CERAMICS GMBH - DESAMANERA SRL - UNIVERSITE MOHAMMED V DE RABAT - - - EUR 877 500 - - - Additive Manufacturing Initiative for Transnational Innovation in Europe - - - EUR 877 500 - - - France - France - France - Germany - Germany - Italy - Italy - United Kingdom - Spain - Belgium - France - France - France - France - Germany - Germany - Italy - Morocco - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - Additive manufacturing (AM) technologies and overall numerical fabrication methods have been recognized by stakeholders as the next industrial revolution bringing customers’ needs and suppliers’ offers closer. It cannot be - dissociated to the present trends in increased virtualization, cloud approaches and collaborative developments (i.e. sharing of resources). AM is likely to be one good option paving the way to Europe re-industrialization and increased - competitiveness. AMITIE will reinforce European capacities in the AM field applied to ceramic-based products. - - - 2021-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - France - - - AMITIE - - - H2020-MSCA-RISE-2016 - - - 734342 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 149 563 - - - A new tool in drug development: mapping of compound-protein interaction using forward genetics - - - EUR 149 563 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Development of new medicines such as chemotherapeutic drugs requires a detailed understanding of their biological mechanism of action. What are the desired and undesired interactions with biological molecules? It is our goal - to found a start-up company that will provide a solution to this challenge. Using novel and ground-breaking approaches we can identify target structures and interaction partners of small bioactive molecules at an unmatched and unprecedented - resolution. ERC PoC funding will be essential to support our activities to identify optimal strategies and initial customers for our service. - - 2018-12-31, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Germany - - - ACUSLABS - - - ERC-2017-PoC - - - 768524 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - UNIVERSITAET STUTTGART - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - ERNST & YOUNG ABOGADOS SLP - - - EUR 606 198 - - - Innovative infrastructure for astronomical research based on stratospheric balloons - - - EUR 606 198,75 - - - Spain - Germany - Germany - Spain - - - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - ORISON addresses an innovative research infrastructure based on scientific instrumentation integrated into movable stabilized balloon platforms. Many Astronomical observations and experiments are severely limited by the - Earth’s atmosphere: atmospheric turbulence, atmospheric absorption, scattering and emissions, bad weather and other phenomena degrade or prevent many astronomical observations. To solve that, scientists utilise specific space missions, such as the - Hubble Space Telescope, whose costs are immense and whose availability is highly restricted. - - - 2017-07-31, closed project - - - 2016-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.2.1."> - - - INFRASUPP-2-2015 - Innovative procurement pilot action in the field of scientific instrumentation - - - CSA - Coordination and support action - - - Spain - - - ORISON - - - H2020-INFRASUPP-2015-2 - - - 690013 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 2 212 500 - - - Systems Neuroscience of Metabolism - - - EUR 2 212 500 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Proopiomelanocortin (POMC)- and Agouti-Related Peptide (AgRP)-expressing, i.e. melanocortin neurons in the hypothalamus, are key regulators of feeding behaviour, glucose metabolism, autonomic responses and higher cognitive - functions. They represent targets for fuel-sensing hormones like leptin and insulin that thereby control key processes in systemic energy and glucose homeostasis. Importantly, resistance to these fuel-sensing signals is known to contribute to the - current obesity and diabetes epidemic. Consequently, altered POMC- and AgRP-neuron regulation in obesity contributes to the development of numerous metabolic alterations. Although the melanocortin neurons as central regulators of metabolism have been - classified according to the expression of their characteristic neuropeptides, it has only recently become clear that even within these populations they represent distinct heterogeneous neurons with respect to their physiological regulation and the - biological responses governed by their specific downstream neurocircuits. However, the molecular nature of heterogeneous POMC and AgRP neuron populations, their specific neurocircuitry architecture and their specific functions still remain largely - unexplored. Therefore, we will employ a wide array of state-of-the-art molecular systems neuroscience and modern mouse genetics approaches to define (1) the anatomical distribution, (2) molecular signature, (3) neurocircuitry architecture, (4) - regulatory principles, (5) specific biological functions, and finally (6) novel druggable regulators of these specific POMC and AgRP microcircuits. We anticipate that the new knowledge generated will not only provide novel insights into the - fundamental principles of CNS-dependent control of metabolism but could also lead to targeting these specific neurocircuits to develop novel, specific, tailor-made therapies for diverse aspects of metabolic diseases for which currently only - insufficient treatment options are available. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - SYNEME - - - ERC-2016-ADG - - - 742106 - - - - - KOBENHAVNS UNIVERSITET - KOBENHAVNS UNIVERSITET - - - EUR 149 956 - - - Electromagnetic to Optics Transducer - - - EUR 149 956 - - - Denmark - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Modern communication and sensing is done with radio- and microwaves on the one hand, and with optical fiber links, on the other. Radio- and microwaves are widely used in commercial and personal communication, as well as in - sensing in, for example, medical diagnostics. Optical communication dominates long distance, point-to-point connections, such as internet. This action aims at the development of a miniature device for efficient conversion between these technological - platforms. Within the AdG INTERFACE we have developed a novel principle for the opto-electromechnical transducer (Nature, 2014) and filed a US patent. We have further made progress in developing an integrated version of the transducer with enhanced - sensitivity. Preliminary market analysis has shown high potential of our device in diverse areas, such as industrial internet of things, airborne intracommunication systems, scientific sensors, measurement instrumentation, radio astronomy, and - nuclear magnetic spectroscopy. This action will include the first tests of the device in a flagship application relevant to NMR spectroscopy—a real life MRI scanner—and an extensive effort towards producing a packaged, fiber-coupled, ultralow-noise - transducer ready for field demonstrations. - - 2019-08-31, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Denmark - - - EMOT - - - ERC-2017-PoC - - - 768491 - - - - - UNIVERSITAT ZURICH - UNIVERSITAT ZURICH - - - EUR 2 103 440 - - - Drivers of Growth in Bank Lending and Financial Crises - - - EUR 2 103 440 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Banking crises are thought to be recurrent phenomena that generally come on the heels of strong credit growth. Their damaging real effects have generated a broad agreement among academics and policymakers that financial - regulation needs to tighten and to obtain a macroprudential dimension that aims to lessen the negative externalities from the financial to the macro real sector. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Switzerland - - - lending - - - ERC-2016-ADG - - - 740272 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 2 500 000 - - - Treating mitochondrial disease caused by pathogenic mtDNA mutations - - - EUR 2 500 000 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - This proposal describes a series of powerful experimental strategies to develop a completely novel treatment for mtDNA mutation disease based on identifying unknown mechanisms controlling mtDNA replication. Several hundred - different mtDNA mutations affect tRNA genes and impair mitochondrial translation leading to human disease. There is typically heteroplasmy with a mixture of wild-type and mutated mtDNA, and the mutations are acting in a “recessive” (loss of function) - way. Very high levels of mutated mtDNA are needed to cause disease in affected patients whereas maternal relatives with high, but sub-threshold levels of mutated mtDNA are completely healthy. The corollary of these observations is that even a small - increase of wild-type mtDNA may efficiently counteract disease in affected patients. This hypothesis will be validated by a series of genetic experiments with mice harbouring single pathogenic mtDNA mutations. Furthermore, novel factors controlling - mtDNA replication will be identified. In particular, we will elucidate the formation and function of the mammalian displacement (D) loop, which provides a switch between abortive and genome length mtDNA replication. This very fundamental problem in - mammalian mitochondrial biology has remained unsolved for decades, but I feel that the innovative experimental strategies I present in this proposal are very powerful and should have a fair chance of being successful. In any circumstance, the project - will provide important molecular insights into novel mechanisms relevant for mammalian mtDNA replication. Over the years I have been strongly convinced that congruent results from in vivo and in vitro studies are needed to obtain reliable mechanistic - insights and this project is therefore based on the close integration of biochemistry, advanced proteomics and state-of-the-art mouse and fly genetics. Finally, I describe a powerful large-scale screening approach to develop small molecular - stimulators of mtDNA replication. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - mtDNA-CURE - - - ERC-2016-ADG - - - 741366 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 2 070 000 - - - Topological Materials: New Fermions, Realization of Single Crystals and their Physical Properties - - - EUR 2 070 000 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - The topologies of the electronic and magnetic structure in reciprocal and real space underlies much of condensed matter physics. Moreover, the properties of single crystals with particular topological electronic structures can - mimic phenomena found in high energy physics and cosmology. New classes of quantum materials are found in insulators and semimetals that exhibit non-trivial topologies: they display a plethora of novel phenomena including: topological surface states; - new Fermions such as Weyl, Dirac or Majorana; and non-collinear spin textures such as Skyrmions. A hallmark of many of these new quantum properties that are derived from fundamental symmetries of the bulk, is that they are topologically protected. - Just recently a general scheme to identify novel Fermions was proposed that is based on the symmetries and the Wyckhoff positions of relevant space groups. These new types of Fermions are a groundbreaking concept beyond the known Dirac and Weyl and - have no high-energy counterparts. The translation of these theoretical concepts into realizable materials is one focus of this proposal. The next step is to apply this approach to magnetic space groups so as to identify new magnetic Fermions. We will - engineer these topological materials via synthesising high quality single crystals and by applying for example high magnetic fields and high pressure, to tune topological phase transitions, electrical transport properties and surface states. - Particularly high-pressure Hall measurements will be developed. Hall measurements allow the investigation of the fundamental electrical transport properties of topological materials such as their carrier densities, oscillation frequencies, - mobilities, and anomalous and topological Hall effects. The PI and her team have already synthesized more than 50 different topological materials as single crystals. To boost topological science in Europe even further a single crystal platform will - be established within the proposed project. - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - TOPMAT - - - ERC-2016-ADG - - - 742068 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 2 499 356,27 - - - Probing chemical dynamics at surfaces with ultrafast atom pulses - - - EUR 2 499 356,27 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Ultra-short light pulses have become invaluable in time-resolved studies in chemistry and physics. But many important processes are initiated by collisions. While lasers have revolutionized experiments using light pulses, - experimentally proven concepts for producing ultra-short pulses of neutral matter are still in their infancy. Hence, our ability to control when a collision occurs is still extremely limited. Recently, we have reported bunch-compression photolysis, - the first demonstrated method for producing ultra-short pulses of neutral matter. Here, photolysis of jet-cooled hydrogen iodide is carried out with femto-second laser pulses whose frequency bandwidth has been spatially ordered. Thus, fast H-atom - photoproducts overtake slow ones, producing an ultra-short pulse.The central objective of this project is to develop bunch-compression photolysis as a tool for ultrafast timing experiments involving collisions of ultrashort pulses of H-atoms at - synchronously photo-excited solid surfaces. Bunch-compression photolysis allows collisions at a surface to be synchronized with photoexcitation on the ps time scale, opening up new ways to study the dynamics of collisions at selectively photo-excited - surfaces that have not yet relaxed. Studies on collision dynamics involving excitons produced in 2D semiconductors is one exciting direction for this work. Experiments on synchronized H atom collisions with vibrationally excited surfaces prepared by - infrared photoexcitation is another - this enables kinetics experiments with surface site-specificity as well as the direct observation of reaction intermediates. The work and ideas presented here show how to overcome the most challenging barrier to - a new class of time-resolved dynamics experiments, opening new frontiers in the study of surface chemistry, where we will begin to understand how selected degrees of freedom of the solid influence collision dynamics and reaction rates. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - HBEAM - - - ERC-2016-ADG - - - 742422 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 2 048 183 - - - Big-Data Analytics for the Thermal and Electrical Conductivity of Materials from First Principles - - - EUR 2 048 183 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - "Thermal conductivity (TC) is a key characteristic of many materials, particularly those used in the energy and environment sectors (thermoelectrics, thermal-barrier coatings, catalysis, etc.). However, TC is largely unknown − - of the 225,000 identified inorganic semiconductor and insulator crystals, only 100 have any TC data available. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - TEC1p - - - ERC-2016-ADG - - - 740233 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 968 125 - - - High Resolution Extreme Ultraviolet Laser Spectroscopy - - - EUR 1 968 125 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Discrepancies between theory and experiments have been fuelling the development of physics from the discrete line spectrum of hydrogen, where classical physics fails, to the Lamb shift, which is unexplained by the Dirac - equation. At the precision frontier, comparisons between theory and experiment have been performed almost exclusively with atomic hydrogen. To progress from there, it very good accuracy. The spectroscopic investigation of muonic hydrogen, which was - successful recently, was the first step in that direction and has brought up a serious challenge to Quantum Electrodynamics (QED). Even though we could solve this problem in the meantime, there might be others waiting to be discovered when leaving - the beaten track of ordinary atomic hydrogen. Besides anti-hydrogen, high resolution laser spectroscopy of singly ionized helium is the next logical item on the list. In addition of representing a hitherto unexplored system, He+ allows for a far - better test than atomic hydrogen due to the QED power series expansion of its energy levels in terms of ZWith the nuclear charge Z and the fine structure constant the disputed terms are of the order of (Z)6. Unlike ordinary hydrogen, He+ can be - readily stored in an ion trap and sympathetically cooled by co-stored ions with an accessible cooling transition. This approach eliminates essentially all dominating experimental uncertainties that we face with ordinary hydrogen today. The 1S-2S - resonance is the sharpest and hence most interesting transition. Its observation requires highly coherent extreme ultraviolet radiation at 60.8 nm which can be generated through high order harmonics from a mode locked laser. The resulting frequency - comb is most suitable for a two-photon transition as photons from pairs of modes combine to deliver the excitation energy. Other applications of such new laser source are foreseeable. - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - XUV-COMB - - - ERC-2016-ADG - - - 742247 - - - - - UNIVERSITAT ZURICH - UNIVERSITAT ZURICH - - - EUR 2 383 444 - - - Noise and robustness in the evolution of novel protein phenotypes - - - EUR 2 383 444 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Living cells are constantly barraged by perturbations that originate within themselves. Especially abundant – far more than DNA mutations – are two kinds of such perturbations. The first is gene expression noise, pervasive - stochastic variation of transcript and protein levels. The second is mistranslation noise, the misincorporation of amino acids by ribosomes during protein synthesis. Organisms and protein molecules can evolve robustness – the persistence of - well-adapted phenotypes – to both kinds of noise. Theory predicts that noise and robustness can affect the adaptive evolution of new proteins, but we do not know whether they help or hinder adaptive evolution. We hypothesize that noise and robustness - can accelerate protein evolution both separately and jointly. To validate this hypothesis, we will evolve light-emitting fluorescent proteins towards new color phenotypes via directed laboratory evolution in E.coli. During evolution, we will - manipulate expression noise by driving FP expression from noisy or quiet promoters, and we will manipulate mistranslation via host strains with low and high mistranslation rates. We will manipulate protein robustness in three biologically important - ways, chaperone overexpression, gene duplication, and stabilizing selection. We will study how fast FPs evolve new colors, and analyze protein evolutionary dynamics through a combination of high-throughput sequencing, engineering of selected adaptive - mutations, and data-driven modeling. Our project will show how a ubiquitous but poorly understood source of phenotypic variation affects protein innovation. It will also help engineers discover new protein functions. Moreover, our work will help - establish FPs as a major platform to study protein evolutionary dynamics. By revealing noise as a new and crucial factor in protein evolution, our observations have the potential to revolutionize molecular evolution research, much like earlier - studies of noise have revolutionized cell biology. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Switzerland - - - NoiseRobustEvo - - - ERC-2016-ADG - - - 739874 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 2 004 375 - - - Exosome and ribosome coupling - - - EUR 2 004 375 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - To date, mechanistic studies on the macromolecular complexes that synthesize or degrade RNAs or proteins have investigated these machines individually to understand how they execute different steps in the gene expression - process. Although the individual complexes catalyze their reactions independently of each other in vitro, increasing evidence suggests that they function in a highly coordinated manner in vivo. The molecular basis for such a coordination remains - largely unknown. During the past five years, our group has focused on deciphering the mechanisms of multiprotein complexes that mediate mRNA turnover in S. cerevisiae. Here, I propose to take these analyses to the next level and visualize how a major - RNA degradation machine, the exosome, is directly coupled to the protein-synthesis machine, the ribosome. In particular, we want to study two different exosome-ribosome assemblies that underpin opposite outcomes of RNA degradation: a constructive - function of the nuclear exosome in the maturation of the large ribosomal subunit and a destructive function of the cytoplasmic exosome in the elimination of ribosome-bound mRNAs. Building on our preliminary data from both the yeast and human systems, - we will use a combination of bottom-up biochemical reconstitutions and top-down endogenous purifications to isolate 1) an exosome complex and its nuclear cofactors bound to a pre-60S ribosomal subunit and 2) an exosome complex and its cytoplasmic - cofactors bound to a stalled 80S ribosome. We will determine the structures of these ~3 - 4 MDa nuclear and cytoplasmic assemblies using the combined information from cryo-electron microscopy and X-ray crystallography approaches. The structural - studies, combined with biochemical and genetic information, will reveal how these machines interact and coordinate RNA metabolism with protein synthesis. Overall, this work will provide important insight into the principles that coordinate different - steps of eukaryotic gene expression. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - EXORICO - - - ERC-2016-ADG - - - 740329 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 999 292 - - - Fossil Fingerprinting and Identification of New Denisovan remains from Pleistocene Asia - - - EUR 1 999 292 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Scientific analyses of ancient biomolecules (proteins, DNA, hard tissues) have transformed our knowledge of archaic hominins present in Eurasia prior to the expansion of modern humans from Africa. In 2010, a finger bone - discovered in Siberia was assigned using DNA to a new, previously unknown human group, the Denisovans. The Denisovans interbred with both Asian Neanderthals and AMH over the past 100,000 years; their geographic distribution is now thought to have - stretched from the Siberian steppes to the tropical forests of SE Asia and Oceania. - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - FINDER - - - ERC-2016-STG - - - 715069 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 872 968,75 - - - Quantum Emitters in non-conventional baths - - - EUR 1 872 968,75 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - The coupling of quantum emitters to a common bath gives rise to intriguing quantum optical phenomena, like super-radiance, non-Markovian dynamics, or dipole-dipole interactions. In recent years, new experimental setups are - emerging where non-conventional baths, with tailored dispersion relations, can be produced. In particular, atoms (the emitters) can be kept in the proximity of photonic crystals (the bath), whose properties can be engineered thanks to the spectacular - progress experienced in nano-fabrication techniques. Low dimensional mate- rials, dispersion relations with Dirac points, or exotic topological features can be designed in photonic crystals, which will dramatically affect the behavior of the - emitters. In this scenario, exotic phenomena, unique possibilities for quantum simulation of both coherent and dissipa- tive dynamics, as well as advanced applications are expected to appear. Presently, a new research area is emerging to investigate - the physics of emitters coupled to non- conventional baths. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - QUENOCOBA - - - ERC-2016-ADG - - - 742102 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 2 378 958 - - - Creating an electron-positron plasma in a laboratory magnetosphere - - - EUR 2 378 958 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - The visible Universe is predominantly in the plasma state. On Earth, plasmas are less common, but they find many applications in industry and are also studied with the goal of providing an abundant energy source for mankind - through fusion energy. The behaviour of plasmas studied thus far, in particular those that are magnetized, is very complex. The complexity manifests itself first and foremost as a host of different wave types, many of which are generically unstable - and evolve into turbulence or violent instabilities. This complexity and the instability of these waves stems to a large degree from effects that can be traced back to the difference in mass between the positive and negative species, the ions and the - electrons. - - 2022-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - PAIRPLASMA - - - ERC-2016-ADG - - - 741322 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 472 000 - - - A Theory of Reliable Hardware - - - EUR 1 472 000 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - The complexity of computing hardware keeps increasing at a rapid pace, with no end in sight. With growing number of components and ongoing miniaturization, hardware engineers struggle with an increasing number and variety of - faults, yet must guarantee correct operation of the system as a whole. This is hindered by a concurrent increase in design complexity, i.e., the trend of integrating ever more diverse circuits into larger systems, which results in a higher complexity - of verifying the correctness of a given design -- especially when providing for the possibility that some components may fail. - - 2022-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - ToRH - - - ERC-2016-STG - - - 716562 - - - - - UNIVERSITAT ZURICH - UNIVERSITAT ZURICH - - - EUR 3 344 108 - - - Towards a multi-ton xenon observatory for astroparticle physics - - - EUR 3 344 108 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Dark matter is one of the greatest mysteries in the Cosmos, as its intrinsic nature is largely unknown. The identification and characterization of dark matter particles is a major endeavor in physics. XENOSCOPE will be a - unique project focussed on essential, cutting-edge research towards a multi-ton dark matter detector using liquid xenon (LXe) as target material. With its low energy threshold, ultra-low backgrounds and excellent energy resolution, a LXe observatory - will be highly sensitive to other rare interactions, such as from solar and supernova neutrinos, double beta decays of 136Xe, as well as from axions and axion-like particles. To design and construct a 50 t (40 t in the time projection chamber, TPC) - detector, a number of critical technological challenges must first be addressed. Fundamental aspects are related to the design of the TPC, including the identification of new photosensors, the optimization of the light and charge collection (hence - the energy threshold and resolution), and the minimization of radioactive backgrounds. XENOSCOPE will address all these aspects through a number of small, medium-size and a full-scale (in the z-coordinate of the TPC) prototypes. The goal is to - specify the required input for the technical design of the 50 t detector, to be realized by the DARWIN consortium which the PI leads. Arrays of VUV-sensitive SiPMs will be studied as novel light sensors, and a 4-π photosensor coverage TPC will be - constructed for the first time. Signal detection will be optimized for both low and high-energy readout, thus drastically increasing the dynamic range of a LXe-TPC. Low-background materials will be identified and characterized not only for the - photosensors and their read-out, but for all the components of the detector. Finally, a full scale TPC in the z-dimension, 2.6 m in height, will be designed, built and operated and electron drift and extraction into the vapor phase over such large - distances for the first time demonstrated. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Switzerland - - - Xenoscope - - - ERC-2016-ADG - - - 742789 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 918 750 - - - Exceptional Quantum Gravity - - - EUR 1 918 750 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Motivated by the overwhelming success of symmetry concepts in formulating basic laws of physics, the present proposal (eQG) seeks to develop a new symmetry based approach to the problem of reconciling Quantum Mechanics and - Einstein’s General Relativity into a consistent theory of Quantum Gravity, regarded by many as the greatest challenge of contemporary theoretical physics. The need for such a theory is most pressing for the resolution of black hole singularities and - the Big Bang, but it is equally crucial to the search for a consistent UV completion of the Standard Model of Particle Physics and the unification of the fundamental interactions. eQG aims to tackle this problem from a new perspective, bringing - together very different strands of development: on the one hand, by paying particular attention to recent advances in our understanding of cosmological singularities and the evidence for novel infinite-dimensional duality symmetries near the - singularity that has emerged in supergravity and string theory, and to recent progress in formulating ‘exceptional geometries’ transcending Riemannian geometry; on the other hand, by exploiting insights from modern canonical quantisation towards a - better understanding of the basic degrees of freedom and the dynamics of quantum space-time. The main focus of eQG will be the ‘maximally extended’ exceptional hyperbolic Kac–Moody symmetry E10, whose uniquely distinguished status makes it a prime - candidate symmetry for unifying the known dualities of string and M theory, for a conceptually precise scenario of emergent (quantum) space and time near the singularity, and finally, for replacing supersymmetry as a guiding principle for - unification. Consequently, the principal goal of eQG will be to explore how this symmetry can define a theory of quantum gravity, how it acts on its fundamental degrees of freedom, what the special features are of the quantised theory, and what - physical predictions can be derived from it. - - 2022-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - eQG - - - ERC-2016-ADG - - - 740209 - - - - - UNIVERSITAT ZURICH - UNIVERSITAT ZURICH - - - EUR 1 500 000 - - - REsummation-Improved moNtecarlo eVEnt geNeraTor - - - EUR 1 500 000 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - With the start of the second run of the Large Hadron Collider and the discovery of a particle compatible with the Standard Model Higgs boson, the high-energy particle physics community faces the task to carry out precise - measurements of the properties of this new particle, in order to establish its nature. At the same time, it will be equally important to keep looking for the yet elusive signs of New Physics. Both tasks rely on the ability to accurately predict the - expected signals and to disentangle them from the known backgrounds. At hadronic colliders like the LHC, accurate modeling of the strong interactions is crucial to interpret the experimental outcomes. - - 2022-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Switzerland - - - REINVENT - - - ERC-2016-STG - - - 714788 - - - - - UNIVERSITAT ZURICH - UNIVERSITAT ZURICH - - - EUR 2 497 500 - - - Time in Medieval Japan - - - EUR 2 497 500 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The project explores time in medieval Japan, taking a new approach to historical articulations of the concept of time, based on the theory of symbolic forms. It will examine symbolic representations and social regulations of - time in a civilisation that is often juxtaposed to contemporary, globalised modernity. We will investigate into medieval Japan as a dynamic and internally differentiated society, and not as a unified “traditional” culture dominated by a qualitative - concept of time. We will focus on its plural ways of registering, measuring, articulating, and regulating time. The aim is to disclose the specific cultural practices operative in the respective ways of negotiating time, and to achieve a more - comprehensive and detailed account of human strategies in dealing with this fundamental restriction of our existence. In a closely coordinated set of case studies, we examine representative spheres connected to various symbolic forms and - socio-cultural agendas: the Zen monastery, the female court, and the market. An intersectional case study explores the symbolic mediations of the menstrual cycle, connecting these spheres and uniting aspects of the physical, ritual and symbolic - regulation of human body time. Each case study explores the symbolic forms prevalent in the respective settings, and the aspects of time that are deemed relevant and selected for symbolic articulation. We will analyse temporal encoding, structure and - application in the regulation of affairs, the competence to account and regulate these processes, and the influence on feelings of dismay in the face of the socio-cultural realities of time. Special attention is paid to the conflicts that arise when - established regimes of temporal regulation and expression clash with each other and with individual experience. The results will be compared to the history of time in the Western world, and integrated into a theory of the symbolic forms of time. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Switzerland - - - TIMEJ - - - ERC-2016-ADG - - - 741166 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 2 457 500 - - - Mapping the Cosmic Gas Supply with ALMA - - - EUR 2 457 500 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - The molecular gas phase is the material in galaxies out of which stars form. As such, it is the quantity that controls the star formation rate of a galaxy, thereby the overall stellar mass build-up, and ultimately galaxy - evolution through cosmic times. In contrast to studies of the stellar mass and star formation, characterizing this fuel supply in galaxies as a function of cosmic epoch is still in its infancy. The ALMA facility now redefines our ability to map out - the cosmic cold gas supply, essentially unknown at present. This ERC proposal is based on extensive approved observational ALMA programs, led by the PI: ASPECS is the first-ever approved ALMA large (150h) program, aimed at providing a comprehensive - view of the baryon cycle from gas to stars over cosmic time. ASPECS will provide 3D molecular scans in two ALMA bands of the Hubble Ultra Deep Field -- the iconic cosmological deep field. A second focus is the detailed characterization of the - molecular gas content at z>6 in host galaxies of the most distant quasars via ALMA. This will assess the role of cold gas in the build-up of the first (t_Universe < 1 Gyr) massive cosmic structures in the Universe, again through significant - approved ALMA programs led by the PI’s group. The studies outlined here will fully capitalize on the unparalleled capabilities of ALMA to map out the cosmic gas supply through cosmic history, and will provide crucial insights to define observational - strategies for JWST (the PI is member of the European JWST/MIRI science team). Through his track record, past achievements in the field of galaxy evolution studies, and through the available proprietary data, the PI is uniquely positioned to lead - this ambitious program, which will define the global state-of-the-art in cosmological galaxy evolution through high-redshift ISM studies. - - 2022-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - Cosmic_Gas - - - ERC-2016-ADG - - - 740246 - - - - - UNIVERSITAT ZURICH - - - EUR 187 419,60 - - - Developing a Financial Econometrics Package for the Julia Programming Language - - - EUR 187 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - Julia is a new programming language started at MIT, with a strong focus on numerical computing. Its key advantage compared to languages like R and Python is that Julia is (just in time) compiled, rather than interpreted. As a - consequence, Julia effectively combines the convenience of these high level languages with the speed of compiled low level languages such as C++ or Fortran. Speed of execution is critical in many applications, including but not limited to those - involving big data. - - - 2020-01-01, ongoing project - - - 2018-01-02 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - juliaeconometrics - - - H2020-MSCA-IF-2016 - - - 750559 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 171 460,80 - - - Quantum Dynamics Beyond the Born-Oppenheimer Picture: Making the most of wave function and trajectory-based approaches - - - EUR 171 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - The experienced researcher, Dr. Guillermo Albareda, and the host supervisor, Prof. Angel Rubio, aim at developing a new predictive and practical approach that overcomes the difficulties that current methods have to treat the - correlated electron-nuclear dynamics in complex systems. - - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - BeBOP - - - H2020-MSCA-IF-2016 - - - 752822 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 171 460,80 - - - Mechanisms of collective predator detection and information transfer in African ungulates - - - EUR 171 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - One benefit of sociality in animals is collective predator detection, which provides early warning of threats and enables more effective escape responses. For collective detection to occur, information regarding the presence - of predators must be transferred from knowledgeable to naïve individuals. The mechanisms of information sharing have rarely been studied outside of laboratory settings, and for most species it is unclear how information transfer is achieved and how - the reliability of transfer is affected by social, ecological, and behavioral factors. Using UAV-based aerial video technology and novel computer vision techniques, The Experience Research (ER) will study the mechanisms of information transfer in - groups of African ungulates in their natural savannah habitats. The ER will observe unperturbed herds, and conduct field experiments in which she present threatening stimuli to groups and observe how awareness of the stimuli spreads through the - group. Using custom-built automated tracking software, the ER will quantify the behavior of every individual within each group and combine this data with computationally reconstructed visual fields and 3D habitat models. This dataset will enable her - to precisely identify the visual information available to each individual continuously throughout each trial and explicitly consider the role of this information in driving individual vigilance strategies in the absence of immediate threats. In - undertaking this project, the ER will adapt quantitative methods developed for laboratory settings for use in stochastic, large-scale field studies. This research programme will shed new light on the benefits of sociality, a classic topic in animal - behavior, and promote the use of novel quantitative approaches in field studies that will advance the field of behavioural ecology. - - 2019-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - UNGULATE - - - H2020-MSCA-IF-2016 - - - 749499 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 483 750 - - - Neural circuits for route planning in goal-directed spatial navigation - - - EUR 1 483 750 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Spatial navigation is a fundamental ability for animals to survive in a geometric space. A prominent feature of rats is their ability to create an internal metric space, or a map, in their brain. While place cells in the - hippocampus are considered key elements of the spatial representation system, the activity of these cells primarily depends on the animal’s instantaneous position; thus it is not clear how the brain computes an estimate of future positions, necessary - for route planning. Although several ideas have been proposed to extract future representations from place cells, how such information is used in downstream brain structures is still largely unknown. I thus propose to clarify the roles of the - hippocampus in the larger context of brain circuits for route planning. A growing body of evidence indicates key roles for the medial prefrontal cortex (mPFC) and the retrosplenial cortex (RSC) in navigation. I hypothesize that RSC, downstream of - hippocampal area CA1, may represent the animal’s future position by making use of information from place cells about positions and movements. The future positions may then be evaluated in mPFC, a downstream target of RSC and CA1, which potentially - represents the spatial proximity to the goal. I will clarify the key circuit dynamics during route decisions among these structures together with the hippocampus. As route planning requires information about positional relationships in the - environment, I will also investigate a role for brief trajectory sequences generated by place cells, or replay, for transferring such information from the hippocampus to RSC. Simultaneous high-density recordings from multiple regions as well as - optogenetic silencing of specific projections are all available in freely behaving rats, and extensive use of computational methods will help decipher the codes in navigation circuits. The studies will provide key insights into how internal models in - the brain influence cognition and behaviour. - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - NavigationCircuits - - - ERC-2016-STG - - - 714642 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 159 460,80 - - - Functional Analysis of Host Genetic Variants: Biomarker Selection Towards Improving Female Subfertility Diagnosis and Treatment - - - EUR 159 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Roughly 15% of couples trying to conceive suffer from subfertility. One of its leading causes is developed pathology in woman’s fallopian tubes (tubal pathology or TP). Persistent infection with Chlamydia trachomatis (CT) is - the single most common cause of TP. Women with a certain genetic makeup are more likely to develop TP after CT infection. I have so far identified 8 host genes and 13 genetic variants associated with CT infection and TP. Their exact function is, - however, not yet elucidated. In this project, I will research the effect of found host genetic factors on CT infection and TP, by analysing their function in a human fallopian tube organoid model. This model optimally simulates in vivo conditions in - the tubes. The host institution offers the technology and expertise for conducting such research. - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - HOST-SELECT - - - H2020-MSCA-IF-2016 - - - 752999 - - - - - UNIVERSITAT ZURICH - - - EUR 175 419,60 - - - Probabilistic neuromorphic architecture for real-time Sensor fusion applied to Smart, water quality monitoring systems - - - EUR 175 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - “ProbSenS” will develop a novel low-power event-driven probabilistic Very Large-Scale Integration (VLSI) architecture for real-time, adaptive and robust multisensor integration. Multisensor integration exploits the extended - coverage of multiple detectors to increase perceptual confidence in Smart Systems, but embedded implementations are yet in their infancy due to the lack of hardware able to infer from the multivariate, nonlinear, time-dependent and noisy signals - supplied by modern sensors. By using principles of how biological systems promptly combine multisensory information and generate meaningful features in dynamic and uncontrolled real-world conditions, bioinspired Generative Deep Neural Network (GDNN) - models are emerging as a powerful, CMOS-amenable computing paradigm to accelerate sensor fusion and enable quick, reliable self-learning and context-awareness under these constraints. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - ProbSenS - - - H2020-MSCA-IF-2016 - - - 747848 - - - - - UNIVERSITAT ZURICH - - - EUR 175 419,60 - - - The evolvability of bacterial multicellularity - - - EUR 175 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - There are numerous evolutionary origins of multicellularity. Yet, only in a few cases was the origin of multicellularity also followed by an enormous diversification of multicellular forms and functions. This raises the - question what determines the evolvability of multicellular phenotypes, i.e. their capacity to undergo evolutionary change? I will study the evolvability of one of the simplest forms of bacterial multicellularity: colony formation in the Bacilli. - Despite their simplicity, Bacilli can express a wide range of colony morphologies. The physical forces that shape these morphologies are well understood. In addition, there is a detailed understanding of the gene regulatory network (GRN) underlying - colony formation and ample of genomic data. I will study how the GRN underlying multicellularity affects its evolvability. First, I will determine which evolutionary changes in the GRN are associated with the diversification of colony morphologies. - To this end, I will construct a phylogenetic tree of the Bacillales, compare all genomes and identify the genetic changes that correlate with changes in colony morphology. Second, I will determine if and how these genetic changes give rise to changes - in colony morphology. I will construct Bacillus subtilis mutants, which harbor the identified genetic changes, and examine how their colonies develop. Since colonies come about through the feedback between cells and their environment, I will use a - unique combination of state-of-the-art biotechnologies to trace the transcriptomic and environmental changes in the colony over time. This will give an extraordinary detailed account of colony development in the Bacilli. Finally, I will examine why - the morphological diversification of colonies was favored by selection, by studying the functional properties of colonies. Altogether, this will be the first comprehensive analysis on the evolvability of multicellularity, thereby giving a unique - glimpse on how evolution innovates. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - EBM - - - H2020-MSCA-IF-2016 - - - 742235 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 479 105 - - - Lifespan Inequalities: Why the age-at-death distribution varies between countries and socioeconomic groups - - - EUR 1 479 105 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Individuals and populations are surviving to ever higher ages. A crucial and timely question for policymakers is whether to direct limited resources toward future life expectancy increases or toward reductions of inequalities - in longevity. These inequalities, hereafter referred to as lifespan inequality but also known as age-at-death variation, are large, infrequently summarized, and impose major costs on individuals and society. In order to formulate effective policies - to reduce lifespan inequality, we need a deeper understanding of the magnitude and causes of divergent age patterns of mortality decline. - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - LIFEINEQ - - - ERC-2016-STG - - - 716323 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 159 460,80 - - - Role of Listerin ubiquitin ligase in MHC-I antigen presentation - - - EUR 159 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Mammalian cells present a fingerprint of their proteome through the display of endogenous peptides on MHC-I complexes. This allows for CD8+ T cells to recognize and kill cells infected with viruses or other intracellular - parasites, or cells accumulating aberrant proteins resulting from malignant transformation. The MHC-I peptides originate from protein degradation by the ubiquitin proteasome system, which is responsible for controlled protein turnover. This would - mean that viral proteins, which are typically very stable, would escape monitoring. Nevertheless, cells are able to mount an MHC-I immune response minutes after viral infection. Most MHC-I presented peptides are therefore thought to originate from - newly synthesized, defective ribosomal products (DRiPs), rather than proteins at the end of their lifespan. Although there is a growing body of evidence showing that antigen presentation is better correlated with protein synthesis rather than protein - stability, characterization of the underlying cellular pathway is lacking. Recently, the E3 ubiquitin ligase Listerin has been shown to mark nascent polypeptides resulting from defective mRNAs for degradation. Here we test the hypothesis that this - pathway contributes to the production of peptides for MHC-I loading. Our major aim is therefore to investigate the involvement of Listerin in antigen presentation, using 3 different approaches: I) proof-of-principle experiments analyzing the rate of - MHC-I presentation of a model protein, comparing the efficiency of its presentation when expressed from an intact or defective mRNA, and when expressed in WT or Listerin knock-out cells; II) global characterization of the MHC-I peptidome of WT and - Listerin knock-out cells using mass spectrometry; III) quantitative analysis of the fraction of newly-synthesized proteins undergoing the RQC pathway, and of its possible correlation with the MHC-I peptidome. - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - IMMUNO-RQC - - - H2020-MSCA-IF-2016 - - - 749932 - - - - - UNIVERSITAT ZURICH - - - EUR 175 419,60 - - - Multi-particle scattering amplitudes for precision collider physics - - - EUR 175 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - Scattering amplitudes determine the probability of interactions between fundamental particles. They are essential ingredients for phenomenological predictions in high-energy physics. Experiments at modern colliders, such as - the Large Hadron Collider (LHC) at CERN, are probing fundamental interactions at previously unexplored scales of energy. The high energy involved in these interactions is responsible for the production of many particles in the final state, which - needs to be theoretically understood with high accuracy in order to make the most out of experimental data. The goal of this research project is the analytic calculation of multi-particle scattering amplitudes at higher orders in perturbation theory, - and in particular the two-loop five-point amplitudes in quantum chromodynamics, needed for theoretical predictions at next-to-next-to-leading order in perturbation theory. These are of great relevance for LHC phenomenology, since our success in - finding new physics can depend on our capability of distinguishing its effects from the large QCD background of multi-particle processes, which needs to be known with high precision. The method used for the calculation builds upon state-of-the-art - techniques, such as multi-loop integrand reduction and generalized unitarity. These techniques exploit the knowledge of the universal analytic and algebraic structure of amplitudes, and are suited for handling the complexity of multi-particle - calculations. The technologies and tools which will be developed for this project are very general and will thus provide a framework useful for future precision calculations, opening up a new frontier for high-precision multi-particle theoretical - predictions for collider experiments. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - MPAmplitudes - - - H2020-MSCA-IF-2016 - - - 746223 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 171 460,80 - - - Global Climate change impact on phenOtype and ePigenomE stability: Accessing plant adaptability through a 2050 simulation model - - - EUR 171 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - One of the key challenges in the 21st century will be food security. Computer modelling using historical data predicts a climate shift towards combination of increasing temperature, rising carbon dioxide (CO2) levels and high - Ultraviolet (UV) radiation. Such climatic change could negatively affect productivity of the agricultural systems and thus availability of food for the growing world’s population, which is a very serious concern. However, most of the current debate - is based on little experimental evidence. Therefore, we aim to address this question by establishing a strong backbone of phenotypic and molecular data in the frame of the proposed project. Our first objective will be to examine the impact of the - predicted 2050 climate on the morphological and physiological performance of the model and the crop plants. Adaptation of plants to environmental cues occurs also at the gene transcriptional level and is widely controlled by epigenetic means. - Therefore, in the second objective we will study plant chromatin changes in response to predicted climatic change and their effects on plant phenotypes. Our study will act as a resource to framework the phenotypic and molecular mechanism by which - these environmental variations affect crop yields and current estimates of future impacts of climate. Hence, the longer term goal of the project is to contribute towards solving the current food security issues by providing valuable resource of data - for scientists along with the strategy makers. - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - COPE-50 - - - H2020-MSCA-IF-2016 - - - 747718 - - - - - UNIVERSITAT ZURICH - UNIVERSITAT ZURICH - - - EUR 1 999 991 - - - Brain networks controlling social decisions - - - EUR 1 999 991 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Successful social interactions require social decision making, the ability to guide our actions in line with the goals and expectations of the people around us. Disordered social decision making – e.g., associated with - criminal activity or psychiatric illnesses – poses significant financial and personal challenges to society. However, the brain mechanisms that enable us to control our social behavior are far from being understood. Here I will take decisive steps - towards a causal understanding of these mechanisms by elucidating the role of functional interactions in the brain networks responsible for steering strategic, prosocial, and norm-compliant behavior. I will employ a unique multi-method approach that - integrates computational modeling of social decisions with new combinations of multimodal neuroimaging and brain stimulation methods. Using EEG-fMRI, I will first identify spatio-temporal patterns of functional interactions between brain areas that - correlate with social decision processes as identified by computational modeling of behavior in different economic games. In combined brain stimulation-fMRI studies, I will then attempt to affect – and in fact enhance – these social decision-making - processes by modulating the identified brain network patterns with novel, targeted brain stimulation protocols and measuring the resulting effects on behavior and brain activity. Finally, I will examine whether the identified brain network mechanisms - are indeed related to disturbed social decisions in two psychiatric illnesses characterized by maladaptive social behavior (post-traumatic stress disorder and autism spectrum disorder). My proposed work plan will generate a causal understanding of - the brain network mechanisms that allow humans to control their social decisions, thereby elucidating a biological basis for individual differences in social behavior and paving the way for new perspectives on how disordered social behavior may be - identified and hopefully remedied. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Switzerland - - - BRAINCODES - - - ERC-2016-COG - - - 725355 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 251 611,20 - - - Temporal predictions in the auditory cortex: neural mechanisms and their specificity across species and stimulus domains - - - EUR 251 611,20 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Following a recent paradigm shift in neuroscience, the brain is often thought to generate active predictions of its environment. Neural predictions of temporal information, in particular, are a current research frontier. A key - challenge is to provide a unifying mechanistic explanation of neural expectations ranging from microscopic electrophysiology, via models of interacting populations of neurons, to macroscopic signals observed non-invasively. Auditory and speech - perception are the optimal testing ground for studying temporal dynamics of predictive processing in the brain, as most auditory signals only gain meaning as temporal sequences. - - - 2021-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Germany - - - BrainPredictDynamics - - - H2020-MSCA-IF-2016 - - - 750459 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 159 460,80 - - - The role of tRNA processing and modifications in protein quality control. - - - EUR 159 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Translation of the genetic code into functional proteins is a fundamental biological process essential for cell survival and function. tRNAs are critical in this process because they recognize the codons on the messenger RNA - and bring the cognate amino acid to the nascent peptide. To become functional, tRNAs undergo a series of processing steps and chemical modifications. Recently, my host group discovered that cells lacking wobble uridine modifications in the tRNA - anticodon display translational slow down, a defect that triggers widespread protein aggregation in yeast and nematodes. These findings were the first to link tRNA metabolism to protein quality control and established tRNA metabolism as a novel layer - in the regulation of protein homeostasis. However, the mechanisms underlying this phenomenon remain unknown. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - MOD-PROT - - - H2020-MSCA-IF-2016 - - - 746340 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 999 998 - - - Structural Studies on Focal Adhesions - - - EUR 1 999 998 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Focal adhesions (FA) are gigantic protein complexes whose formation is triggered by integrin ligand activation. FAs represent (1) a sensing platform and anchoring points to the outside environment and, (2) a machinery to - transduce this information by initiating signaling pathways for cell growth, survival, migration and polarization. Failure in the regulation of FA leads to developmental defects and contributes to the formation of aggressive cancers. Hence, - understanding FA formation is the basis for counteracting these detrimental effects. Recently, mass spectrometry and advanced light microscopy clarified players involved in the FA assembly and implicated sophisticated regulation networks of membranes - and actin cytoskeletons in the growth of FAs. However, the molecular mechanisms of FA formation and signaling still remain unclear. - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - FocAd - - - ERC-2016-COG - - - 724209 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 171 460,80 - - - Active Resonator Development for nano-EPR of single crystal proteins - - - EUR 171 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - In order to keep up with societal challenges of the 21st century, we must devise sustainable ways to efficiently store and retrieve energy from hydrogen. This “hydrogen economy” is one path for the future of clean energy. - Nature’s solution to this challenge is a branch of enzymes called hydrogenases which typically use an organometallic active-site to reversibly split molecular hydrogen to hydrogen-ions and energy, in the form of electrons. Here, we choose to focus on - [FeFe]-hydrogenase due to its high catalytic behavior. To understand these metallo-enzymes we must be able to study the enzymes grown as a single crystal. Single crystal protein Electron Paramagnetic Resonance (EPR) experiments are the ultimate - method to study the paramagnetic states of hydrogenases and obtain the full magnetic interactions reflecting the electronic structure of the active site. Ultimately the catalytic activity of the hydrogenase can be understood by relating the - information of the magnetic principal axes to the known protein structure of the enzyme. However, the application of single-crystal EPR is severely limited by the small crystals sizes that are usually available (sub-nanoliter to nanoliter volumes). - The Key Enabling Technologies outlined in this fellowship have the potential to increase the sensitivity of EPR by a factor of 30 through the application of highly innovative concepts based on planar micro-resonators (PMR). This technology provides - the sensitivity needed for the applicant to be the first to study single crystals of the [FeFe]-hydrogenase enzyme with EPR and advance the “hydrogen economy”. - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - Act-EPR - - - H2020-MSCA-IF-2016 - - - 745702 - - - - - UNIVERSITAT ZURICH - - - EUR 175 419,60 - - - Neuromorphic EMG Processing with Spiking Neural Networks - - - EUR 175 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - The aim of the NEPSpiNN project is to realize a neuromorphic event-based neural processing system that can directly interface with a commercial surface electromyography (sEMG) for the extraction of signal features and - classification of the motor neurons output activities. - - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - NEPSpiNN - - - H2020-MSCA-IF-2016 - - - 753470 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 159 460,80 - - - Targeting of host proteins by unrelated pathogen effectors and their surveillance by allelic immune receptors - - - EUR 159 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Pathogens secrete effectors into host cells to promote virulence and often establish disease by interception of basal defence components. One widespread mechanism of disease resistance in plants requires nucleotide-binding - oligomerization (NOD)-like receptor (NLR) genes. Recognition of an effector by a cognate NLR prevents pathogen proliferation. A co-evolutionary arms race between the host barley and the pathogenic powdery mildew fungus Blumeria graminis forma - specialis hordei (Bgh) has driven the functional diversification of allelic NLR variants encoded at the MLA disease resistance locus (for Mildew locus A). Recent work revealed that Bgh effectors detected by allelic MLA receptor variants are - unexpectedly sequence-unrelated and evolved independently from different ancestors. Additionally, the MLA orthologs in wheat and rye, Sr33 and Sr50, confer isolate-specific resistance to the stem rust pathogen Puccinia graminis forma specialis - tritici (Pgt). This is remarkable because rust and mildew fungi belong to different phyla and cannot encode sequence-related effectors. MLA variants can therefore not have diversified to directly bind sequence-related effectors and thus monitor - effector-mediated modifications of host targets conserved between different cereals. - - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Germany - - - TOPPER - - - H2020-MSCA-IF-2016 - - - 742263 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 171 460,80 - - - Middle Palaeolithic projectile weapon TIPs: a regional and assemblage scale perspective on Neanderthal POINT technologies across Europe - - - EUR 171 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Stone-tipped hunting weapons are an important marker of the technical and cognitive capacities of Palaeolithic hominins and represent a crucial tipping point in human behavioural evolution. Neanderthals were skilled hunters, - as indicated by zooarchaeological and isotope analyses, but preserved remains of organic spears are sparse and potential lithic weapon tips are not ubiquitously present during the Middle Palaeolithic (MP, ca.300,000-40,000BP). Unravelling this enigma - and reconstructing the technology underlying MP hunting events is one of the key challenges in studies of Neanderthal behaviour. - - 2019-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - Germany - - - TIP-N-POINT - - - H2020-MSCA-IF-2016 - - - 745662 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 171 460,80 - - - Mapping the Intraflagellar Transport - A High-resolution Study of Intraflagellar Transport Trains in Chlamydomonas Cells - - - EUR 171 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Cilia are highly conserved eukaryotic organelles that, with the exception of fungi and higher plants are present in nearly all types of organisms from protists to mammals. Through their motility, sensory, and signaling - functions cilia play crucial roles in human physiology and development. Defects in cilia have profound impact on human health. Cilia assembly requires a dedicated protein shuttle, intraflagellar transport (IFT), a bidirectional motility of - multi-megadalton protein arrays along ciliary microtubules. Although the overall mechanism of transport is generally described, complete high resolution structural description is necessary for the detailed understanding of this complex system. - - 2019-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - TRAIN SPOTTING - - - H2020-MSCA-IF-2016 - - - 753954 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 159 460,80 - - - Quantum Artificial Neural Networks with Tensor Network Algorithmus - - - EUR 159 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - During the recent years, modern machine learning (ML) has sparked a revolution in areas so diverse as computer vision, voice recognition, medical diagnosis and finance. On its own, quantum information processing (QIP) has also - gained tremendous momentum and a novel field, quantum machine learning (QML), has emerged from the intersection of the two disciplines. Interestingly, much of the understanding underlying the last revolution of ML is strongly connected to insights - gained from condensed matter and statistical physics. It is then natural to use well-understood techniques to describe quantum many-body systems, namely, tensor networks (TN) in the context of ML. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - Q-ANNTENNA - - - H2020-MSCA-IF-2016 - - - 748549 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 171 460,80 - - - A microfluidic cryofixation method for time-resolved correlative microscopy - - - EUR 171 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Correlative microscopy, connecting live-cell fluorescence microscopy with electron microscopy (EM), is a powerful tool to relate a dynamic cellular process to the relevant cellular ultrastructure leading to better - understanding of fundamental mechanisms, and further, the underlying cause of disease. This is not only important for fundamental science but can guide diagnostic and treatment efforts for virtually any affliction, ranging from Alzheimer’s disease, - to HIV, to cancer. In this work, I propose a novel microfluidic cryofixation method that enables time-resolved correlative microscopy. The new method dramatically improves the time resolution with which live images can be correlated to EM images by - eliminating the need to transfer the sample from the light microscope to a dedicated cryofixation machine. Current state-of-the-art systems require at least one second while preparation times up to a few minutes are common. Here I propose a new - microfluidics-based paradigm that will overcome this barrier by carrying out cryofixation directly within the field of view of a light microscope. This method allows a dynamic process to be arrested at a known time, so that it can be correlated to - cellular ultrastructure in EM images. This new method is a critical advance for studying dynamic processes such as membrane trafficking, cell division, and synaptic transmission. - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - umCryofix - - - H2020-MSCA-IF-2016 - - - 749830 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 931 303 - - - The chemistry and physics of RNP granules: how they form, age and cause disease - - - EUR 1 931 303 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Recent studies suggest that defective ribonucleoprotein (RNP) granules and altered RNA processing cause neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). However, - defective RNP granules only develop late in life, suggesting that young cells have mechanisms in place to prevent their formation. We recently demonstrated that physiological RNP granules form through phase separation in the cytoplasm and adopt a - liquid-like state, but with time transition into an aberrant disease-associated state with solid material properties. Focussing on this conceptual advance, we will - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - PhaseAge - - - ERC-2016-COG - - - 725836 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 159 460,80 - - - Population genomics and experimental evolution of ribosomal RNA gene variants in Arabidopsis thaliana - - - EUR 159 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - The central importance of ribosomal RNA genes (rDNA) for our understanding of biology cannot be overstated: they are evolutionarily the oldest genes, they are the most highly expressed genes in any organism, and their - expression is central to cellular growth. Because of the requirement for large quantities of rRNA, eukaryotic genomes contain clusters with hundreds to thousands of rDNA copies arranged in tandem. Despite their high copy number, there is little - sequence variation across all rDNA genes within an individual and across individuals in a given species, due to the still mysterious process of concerted evolution. Since not all rDNA copies are expressed, we can already suspect that selection cannot - act directly on all rDNA copies. Although our understanding of concerted evolution, and the molecular mechanism how it is achieved (homogenization), has improved over the last decades, no attempt to study it in the context of silent or active rDNA - clusters has been made. In the described research programme I will take full advantage of the model plant Arabidopsis thaliana to attack this important connection. The diversity of genetic resources available such as experimental populations to - effectively unlinked its two rDNA clusters, the large catalog of over 1,001 publicly available re-sequenced genomes combined with corresponding expression data, as well as its accessibility for genetic manipulation make it an ideal system to pursue - the following specific aims: (1) Perform a population genomic analysis of the sequence variability within silent and active rDNA clusters, (2) Generate targeted induced mutations in rDNAs by genome editing to (3) describe the fate and fitness of both - natural rDNA variants and newly induced mutations. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - rDNAevol - - - H2020-MSCA-IF-2016 - - - 752846 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 159 460,80 - - - Modelling superconductivity and spin-related effects in hybrid molecular/two-dimensional materials - - - EUR 159 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - At the intersection of materials science, solid-state physics and quantum chemistry, the design of novel materials in which two or more physical properties are combined into the same solid is currently attracting important - attention. In this project, we propose the development of a new generation of hybrid molecular/two-dimensional materials formed by a coordination complex processed into a two-dimensional superconducting substrate (e.g. CuPc@NbSe2 or [V(C3S5)3]@TaS2). - The selected molecules to form such architectures are nanomagnets that can be used as molecular spin qubits, the irreducible components of any quantum technology. By using state-of-the-art first-principles methods combined with recent theoretical - developments in the host group we intend to establish a full theoretical and computational framework for the rational design of these new hybrid nanomaterials, which can potentially enable the coherent coupling between distant molecular spin qubits - through new superconducting phases. With this aim in mind, we will simulate their electronic properties in the normal and superconducting phase, as well as the spin-related effects that will take place due to the interplay between molecular magnetism - and superconductivity at the nanometre scale. SuperSpinHyMol will be hosted by a leading expert in the field, Prof. Ángel Rubio, director of the MPSD (Germany) and will also involve collaboration with top international experimental groups, which will - fabricate and characterise the proposed materials. Thus, the theoretical results of this project will be benchmarked against high-resolution experiments and refined when necessary. In the long-term, the progress of this project is expected to have - profound impacts on materials science, condensed matter physics, as well as molecular magnetism, providing the foundations to guide the design of new nanodevices using chemical engineering for future advances in quantum computing and molecular - spintronics. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - SuperSpinHyMol - - - H2020-MSCA-IF-2016 - - - 751047 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 159 460,80 - - - Multidimensional Analysis of Axis Patterning in Plant Embryo - - - EUR 159 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Plant cells are immobile, therefore positional signaling is essential for body patterning. While many genes involved in positional signaling in plants are known, we currently lack a mechanistic understanding of their - functions. Embryonic axis pattering is the earliest and simplest instances of positional signaling. In Arabidopsis thaliana, embryo is initially radial symmetry. Soon after, the embryo switches to bilateral symmetry and development continues along - the newly-established axis. How these patterns emerge from a small group of homogeneous cells remains a fundamental unanswered question in developmental biology. Answering this question requires an in-depth analysis of the spatio-temporal - relationship between gene expression and cellular patterns. Today, advanced microscopy and latest image analysis allow us to quantify division, growth and gene expression in individual cells throughout embryogenesis. The host group has been studying - the regulatory role of homeobox proteins, PHABULOSA (PHB) and PHAVOLUTA (PHV). Distribution of PHB/PHV protein is restricted by microRNA to apical embryo, triggering embryonic shoot formation. If the PHB/PHV distribution is a positional signal - reflecting apical-basal axis, how do they regulate cellular growth and division patterns to establish axis? I will generate a 4D map of axis patterning, extract high quality quantitative data to develop spatial computer models, and examine the - interplay between geometry and genetic regulation on axis patterning. I will also apply same approaches to study embryos in other Brassicaceae species. Such comparative developmental analysis will reveal the core mechanism of axis formation shared - among these species and also provide insights into the origins of their embryonic morphological diversity. - - 2019-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - MAAP - - - H2020-MSCA-IF-2016 - - - 753138 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 753 125 - - - Solving The Pathway of LADDERane biosynthesis - - - EUR 1 753 125 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Ladderanes are highly unusual hydrocarbon moieties with linearly concatenated cyclobutane rings. They are found in the membranes of bacteria performing anaerobic ammonium oxidation (“anammox”). How these complicated molecules - are produced is expected to involve both novel enzymes and specially evolved versions of known proteins, but the details remain enigmatic. How do these enzymes assemble such intricate carbon skeletons? How do they control the complex stereochemistry - involved? How do they deal with the typical nonreactivity of hydrocarbons? And how do they overcome the ring strain inherent in these molecules? Answering these and other questions about the molecular mechanism of ladderane biosynthesis will open up - new frontiers in enzymology. - - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - STePLADDER - - - ERC-2016-COG - - - 724362 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 171 460,80 - - - Molecular mechanisms of the mechanical interaction between the cell nucleus and the actin cytoskeleton - - - EUR 171 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - The cytoskeleton plays a pivotal role in growth, development, and disease by sensing mechanical stress and mediating structural remodeling and cell functional responses. The cytoskeleton, which is linked directly to the - nuclear lamina and thereby to chromatin, has recently been proposed to impact on chromatin remodeling and transcriptional activity. However, the mechanisms and biological consequences of force-dependent chromatin remodeling have remained elusive. - Within this context main goals for my project are 1) to characterize nuclear rheology and stress transmission over the nuclear-cytoskeletal linkage, 2) to identify molecular mechanisms of force transmission into the nucleus and 3) to develop a - numerical model of cell contractility and remodeling to systematically and quantitatively investigate the stress transmission to the nucleus to test my hypothesis that global force application to the nucleus can control nuclear mechanics, chromatin - structure and transcriptional activity in a predictable, biologically meaningful way. - - 2019-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - MiMEtiC - - - H2020-MSCA-IF-2016 - - - 748004 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 159 460,80 - - - Investigating inflammatory signaling by combining phospho- and ubiquitin proteomics with CRISPR/Cas9 technology - - - EUR 159 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Deregulation of pro-inflammatory cytokine signalling is the underlying cause for many inflammatory diseases. Thus, understanding the molecular mechanism of cytokine signalling is necessary to develop suitable therapies. The - enormous complexity of cytokine cascades has however impeded the development of new therapies. To shed more light into these intertwined signaling cascades, I plan to use a proteomics approach that allows the identification of signalling mechanisms - in a multi-dimensional and unbiased fashion. The recent development of the EasyPhos protocol in the Mann laboratory will allow me to take an unprecedented look at phosphorylation events occurring in cells stimulated by single and by combinations of - disease relevant cytokines. Simultaneously I will be able to detect changes in the ubiquitinome using the di-Gly enrichment strategy. By combining phosphoproteomics and ubiquitin proteomics with the CRISPR/Cas9 technology to delete and modify members - of diverse signaling pathways, I will be able to analyze the role of these players and their post translational modifications in the respective signalling pathways. This study will therefore investigate the mechanisms and the relationship between - phosphorylation and ubiquitylation in cytokine signalling in an unprecedented way and has the potential to result in the identification of new therapeutic strategies for the treatment of a range of inflammatory diseases. - - 2019-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - Cytokineproteomics - - - H2020-MSCA-IF-2016 - - - 746329 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 150 000 - - - Active Organ Phantoms for Medical Robotics - - - EUR 150 000 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Robot-assisted and minimally invasive medical procedures are impacting medical care by increasing accuracy, reducing cost, and minimizing patient discomfort and recovery times after interventions. Developers of commercial - robotic surgical systems and medical device manufacturers look for realistic phantoms that can be used in place of animal experiments or cadavers to test procedures and to train medical personnel. Existing phantoms are either made from hard - materials, or they lack anatomical detail, and they are mainly passive and thus unrealistic. - - - 2018-08-31, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Germany - - - ACTIVEPHANTOM - - - ERC-2016-PoC - - - 737530 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 171 460,80 - - - Identifying and deciphering the mechanism of the cellular machinery responsible for disaggregation of intracellular prion-like Tau aggregates - - - EUR 171 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Tauopathies are a group of neurodegenerative diseases, the most common of them being Alzheimer’s disease, which are associated with the aggregation of protein Tau in the brain. Despite major research efforts world-wide, the - mechanism of Tau aggregation and its pathogenesis giving rise to such neurodegenerative diseases is not yet understood. Therapeutics to cure these tauopathies, including Alzheimer’s disease, are urgently needed. We aim to identify the conditions, the - cellular machinery responsible and the mechanism of disaggregation of intracellular prion-like Tau aggregates in HEK293 cell lines, with one condition already been identified (starvation). For identifying the conditions of disaggregation, high - resolution confocal microscopy will be used for visualizing intracellular Tau aggregates tagged with yellow fluorescence protein (YFP). For deciphering the cellular components responsible for disaggregation, the proteins associated with the - aggregates will be identified using quantitative mass spectrometry from SILAC (stable isotope labeling with amino acids in cell culture) labeled cells. Moreover, candidate factors will be downregulated by siRNA to establish their involvement in - aggregate disassembly. Such components individually and in combination will then be analyzed for their disaggregation activity in vitro using filter trap assay for the quantification of disaggregation. Cryo-electron tomography of Tau aggregates under - various conditions (e.g. during disaggregation) will be carried out in collaboration with Prof. Wolfgang Baumeister (MPIB). Besides contributing to the benefit of humankind, the proposed research work on neurodegenerative diseases will allow me to - grow as a researcher and will help me in realizing my true potential as a scientist. The MPIB and the Hartl lab in particular will play an important role in this regard due the availability of state-of-the-art research facilities and an - intellectually stimulating environment. - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - REVERSING TAUOPATHY - - - H2020-MSCA-IF-2016 - - - 749370 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 159 460,80 - - - Minirhizotron: Phenology And Root TraitS - - - EUR 159 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Mr.PARTS investigates plant belowground carbon investment and the timing of root development. Root turnover is an important part of global carbon (C) cycles and plants may alter investment into root systems due to nutrient - imbalances or droughts as well as under anthropogenic global change. However, soils are difficult to study and root biomass is highly spatially and temporally variable, especially as seasonal timing (phenology) of aboveground plant events may affect - resource investment and growth periods belowground. I focus on advancing specially designed camera systems for belowground observatories (minirhizotrons; MR) for non-destructive root/soil system observation and repeatable quantification of root - biomass, life/death status and traits, using frequent automated data collection and automatic data processing. I will develop new MR instruments and deploy them first in a greenhouse-based mesocosm at the host institution in a controlled and well - monitored setting, then a transfer to the field in a thoroughly instrumented (e.g. multiple height eddy covariance CO2, above-ground phenology cameras, soil lysimeters) study site as part of an ecosystem-scale experiment manipulating nutrient - stoichiometry in a seasonally dry savanna in Spain. Data streams from the MR instruments will be processed by machine learning techniques and compared and calibrated against manual measurements of root biomass and root traits made via conventional - destructive soil coring as well as whole system above-ground phenology, water and carbon budgets, to identify links between above- and belowground phenology as well as root control over ecosystem C fluxes. In addition, a paired 13C isotope labelling - experiment will investigate C partitioning to non- root biomass building pools (e.g. root exudates, mycorrhizal fungi, maintenance respiration) to produce an integrated budget of plant belowground C investment and the controls on root production. - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - Mr.PARTS - - - H2020-MSCA-IF-2016 - - - 748893 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 500 000 - - - Innate Immune Cell Swarms: Integrating and Adapting Single Cell and Population Dynamics in Inflamed and Infected Tissues - - - EUR 1 500 000 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Neutrophils are essential effector cells of the innate immune response. Intravital microscopy studies have recently changed our perspective on neutrophil tissue dynamics. They revealed swarm-like migration patterns in several - models of inflammation and infection: Neutrophil populations show strikingly coordinated behavior with phases of highly directed chemotaxis and clustering at local sites of tissue damage. My previous work established that neutrophils self-amplify - this swarming response by auto-signaling, which provided the first molecular basis for the collective nature of neutrophil swarms (Lämmermann et al., Nature 2013). However, we are still at the beginning of unraveling the molecular pathways behind - this newly discovered phenomenon. - - - 2022-01-31, ongoing project - - - 2017-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - IMMUNE CELL SWARMS - - - ERC-2016-STG - - - 715890 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 998 750 - - - Enforced ATP wasting as a general design principle to rationally engineer microbial cell factories - - - EUR 1 998 750 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - One global challenge of humanity in the 21st century is the shift from a petrochemical to a bio-based production of chemicals and fuels. An enabling technology towards this goal is metabolic engineering which uses - computational and experimental methods to construct microbial cell factories with desired properties. While it has been shown that genetically engineered microorganisms can, in principle, produce a broad range of chemicals, novel approaches to - improve the performance of those strains are urgently needed to develop economically viable bioprocesses. - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - StrainBooster - - - ERC-2016-COG - - - 721176 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 499 813 - - - Emergent properties of cell surface glycosylation in cell-cell communication - - - EUR 1 499 813 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - The surface of every living cell is covered with a dense matrix of glycans. Its particular composition and structure codes important messages in cell-cell communication, influencing development, differentiation, and - immunological processes. The matrix is formed by highly complex biopolymers whose compositions vary from cell to cell, even between genetically identical cells. This gives rise to population noise in cell-cell communication. A second level of noise - stems from glycans present on the same cell that disturb the decoding of the message by glycans binding receptors through competitive binding. Glycan-based communication is characterized by a high redundancy of both glycans and their receptors. Thus, - noise and redundancy emerge as key properties of glycan-based cell-cell communication, but their extent and function are poorly understood. - - 2022-01-31, ongoing project - - - 2017-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - GLYCONOISE - - - ERC-2016-STG - - - 716024 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 239 860,80 - - - Stellar Populations and Dynamics: a comprehensive IMF analysis - - - EUR 239 860,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - The number distribution of stars by mass in a stellar system, at birth, is given by the initial mass function (IMF). The IMF not only regulates the chemical enrichment of a galaxy, but it also determines its spectrum and the - mass scale. Moreover, it is the bridge between the physics and properties of individual stars and the light that we observe from distant galaxies. Therefore, the IMF constitutes a fundamental piece in modern Astrophysics. Since the pioneers works - suggested an invariant IMF in all star-forming systems, the universality of the IMF has been a common assumption in every extra-galactic study over the last 50 years. However, recent claims of IMF variations in nearby massive galaxies have challenged - this standard picture. The Stellar Populations and Dynamical (SPanD) project aims to perform critical study of these IMF variations, by combining both stellar populations and dynamical techniques to derive the IMF in nearby and high-redshift objects. - Given the strong dependence of most of the astronomical observables on the IMF, a comprehensive IMF analysis as proposed in SPanD is crucial to better understand our observations, and ultimately, to understand how galaxies have formed and evolved. - - 2020-01-15, ongoing project - - - 2017-01-16 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Germany - - - SPanD - - - H2020-MSCA-IF-2015 - - - 702607 - - - - - UNIVERSITAT ZURICH - UNIVERSITAT ZURICH - - - EUR 150 000 - - - Towards clinical trials for a novel treatment for stroke - - - EUR 150 000 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Stroke is the leading cause of adult disability and represents a major health problem in the EU and the Western world. Despite available acute care treatment and rehabilitation therapies, more than half of the patients remain - disabled and there is a large unmet medical need accordingly. Regeneration of interrupted nerve fiber tracts and plastic “hardware” changes in the adult mammalian central nervous system are extremely restricted, a phenomenon which represents a key - reason for the low degree of recovery following CNS injuries including stroke. The molecular impediments that form the basis of this phenomenon are neurite growth inhibitory proteins expressed in central nervous system myelin, in particular the - membrane protein Nogo-A which was discovered by our group. Importantly, antibodies directed against Nogo-A have been shown to induce axonal regeneration, enhance plastic circuit rearrangements and mediate significant improvements in functional - recovery in rodent and non-human primate models of stroke and spinal cord injury. As recently shown in the ERC advanced grant supported the project ‘Nogorise’, almost full functional recovery was observed in rats with large strokes when anti-Nogo-A - antibody treatment was followed by intensive rehabilitative training. As currently no therapy for human stroke patients beyond acute care and rehabilitation exists, there is a substantial market opportunity for the anti- Nogo-A therapy. The proposed - activities within the present project aim at further establishing preclinical proof-of-concept for an anti-Nogo-A administration paradigm translatable to human stroke patients and development of human antibodies targeting Nogo-A. The expected data - package will allow the critical transition from preclinical to clinical development and support the development of a comprehensive business strategy. - - 2018-08-31, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Switzerland - - - NOGOPROOF - - - ERC-2016-PoC - - - 727444 - - - - - UNIVERSITAT ZURICH - - - EUR 175 419,60 - - - Optical Interrogation of Hippocampal Dentate Granule Circuit Dynamics in Health and Disease - - - EUR 175 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - Understanding the cellular and synaptic basis of memory remains a central goal of modern neuroscience. Physical traces of memory exist as an enduring, experience-dependent change in neural activity in response to learning. In - the hippocampus, a key region of the mammalian brain involved in memory formation and recall, new neurons are continually generated in the dentate gyrus (DG) where they form an integral part of the existing functional circuitry. Despite its key - position in the hippocampal formation, however, the function of DG and its adult-born neurons in vivo has not been carefully investigated. Here, by applying transgenic and optogenetic approaches – including multicolour genetically encoded activity - reporters – together with longitudinal two-photon imaging, we aim to study functional dynamics and plastic changes in DG in health and disorder. We propose that activity patterns in DG cell populations show activity-dependent changes during learning - and construct a cellular and circuit basis for contextual memory engrams. We will also investigate how synaptic alterations in excitation-inhibition balance and defects in adult neurogenesis in DG lead to neurological disorders such as Rett syndrome. - - 2018-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - Circdyn - - - H2020-MSCA-IF-2015 - - - 709288 - - - - - UNIVERSITAT ZURICH - UNIVERSITAT ZURICH - - - EUR 1 500 000 - - - Decoding cell-to-cell variation in genome integrity maintenance - - - EUR 1 500 000 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Cells must ensure the integrity of their genome, and failure to do so can lead to mutations and cause disease. A sophisticated molecular network senses genomic lesions and coordinates their faithful repair with other DNA - transactions, including transcription and DNA replication. Research over the last years has significantly advanced our understanding of the DNA damage response and continues to provide crucial insights that explain how cells deal with genotoxic - stress to avoid malignant transformation. - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Switzerland - - - DiVineGenoMe - - - ERC-2016-STG - - - 714326 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 257 860,80 - - - Characterizing Function Genetic Variants Linking Immunity and Psychiatric Disorders - - - EUR 257 860,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Understanding genetic risk for disease is one of the major goals in human genetics. Genome-wide association studies (GWAS) have identified thousands of genetic variants associated with complex human diseases, the majority of - them locating in regulatory regions outside of genes. The identification of functional regulatory variants underlying such GWAS associations and understanding their pattern of activity is the key for understanding biological processes behind each - genetic association to disease – and without such understanding, targeted interventions and drugs to affect the relevant pathways are not possible. - - 2020-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Germany - - - IMAGENE - - - H2020-MSCA-IF-2015 - - - 706636 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 499 437,50 - - - Computer-Assisted Language Comparison: Reconciling Computational and Classical Approaches in Historical Linguistics - - - EUR 1 499 437,50 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - By comparing the languages of the world, we gain invaluable insights into human prehistory, predating the appearance of written records by thousands of years. The traditional methods for language comparison are based on manual - data inspection. With more and more data available, they reach their practical limits. Computer applications, however, are not capable of replacing experts' experience and intuition. In a situation where computers cannot replace experts and experts - do not have enough time to analyse the massive amounts of data, a new framework, neither completely computer-driven, nor ignorant of the help computers provide, becomes urgent. Such frameworks are well-established in biology and translation, where - computational tools cannot provide the accuracy needed to arrive at convincing results, but do assist humans to digest large data sets. - - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - CALC - - - ERC-2016-STG - - - 715618 - - - - - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - JOHANNES GUTENBERG-UNIVERSITAT MAINZ - THE UNIVERSITY OF EXETER - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - PHOTEK LIMITED - PANEPISTIMIO KRITIS - - - EUR 3 999 250 - - - Ultrasensitive chiral detection by signal-reversing cavity polarimetry: applications to in-situ proteomics, single-molecule chirality, HPLC analysis, medical diagnostics, and atmospheric studies - - - EUR 3 999 250 - - - Greece - Switzerland - United Kingdom - Germany - United Kingdom - Germany - United Kingdom - Greece - - - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - Chirality is a fundamental property of life, making chiral sensing and analysis crucial to numerous scientific subfields of biology, chemistry, and medicine, and to the pharmaceutical, chemical, cosmetic, and food industries, - constituting a market of 10s of billion €, and growing. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-01-2016-2017 - FET-Open research and innovation actions - - - RIA - Research and Innovation action - - - Greece - - - ULTRACHIRAL - - - H2020-FETOPEN-1-2016-2017 - - - 737071 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 443 000 - - - Connecting SOLar and stellar Variabilities - - - EUR 1 443 000 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - The proposed project aims at answering four general questions of high scientific importance: - - 2021-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - SOLVe - - - ERC-2016-STG - - - 715947 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 171 460,80 - - - Modelling 2D Transition Metal Dichalcogenide Heterostructures - - - EUR 171 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Although TMDs have been studied for decades, studies have been mostly limited to bulk materials. The properties of TMDs in atomically thin 2D forms can be significantly different from those in the bulk, such as the size of the - band gap, the nature of the band gap (direct versus indirect), the existence of tightly-bound charged excitons. The physics of heterostructures formed by stacking different kinds of TMD layers are even more versatile and unexpected. While recent - studies have experimentally demonstrated the possibility of synthesizing such novel 2D materials, the present project aims to study these new types of materials from a theoretical standpoint. We will perform state-of-the-art first-principles - simulations using the most advanced exchange-correlation functionals developed in the host group for the accurate description of dynamical and charge transfer process within the time dependent density functional theory (TDDFT) as well as many-body - perturbation approaches using the GW self-energy and including excitonic effects at the level of the Bethe Salpeter equation. We will also develop and implement new multi-scale algorithms in the codes needed to handle some of the tasks detailed in - the project. This European Fellowship project will be hosted by a leading expert in the field, Prof. Angel Rubio of the University of the Basque Country (Spain). The project will also involve collaboration with top international experiment groups. - The theoretical results acquired in this project will be used to guide and compare to experimental results with the goal of developing novel devices for future advances in nanoelectronics, photoelectronics and plasmonics. The progress of this project - in exploring and understanding new physics of 2D TMDs and developing novel devices will have profound impacts on condensed matter physics, material science, as well as nano- and bio-science in the next decade. - - 2019-03-02, ongoing project - - - 2017-03-03 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - MODHET - - - H2020-MSCA-IF-2015 - - - 709382 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 836 070 - - - Microstructured Topological Materials: A novel route towards topological electronics - - - EUR 1 836 070 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Topological semi-metals such as Cd3As2 or TaAs are characterized by two bands crossing at isolated points in momentum space and a linear electronic dispersion around these crossing points. This linear dispersion can be mapped - onto the Dirac- or Weyl-Hamiltonian, describing relativistic massless fermions, and thus relativistic phenomena from high-energy physics may appear in these materials. For example, the chirality, χ=±1, is a conserved quantity for massless fermions, - separating the electrons into two distinct chiral species. A new class of topological electronics has been proposed based on chirality imbalance and chiral currents taking the role of charge imbalance and charge currents in electronics. Such devices - promise technological advances in speed, energy efficiency, and quantum coherent processes at elevated temperatures. - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - MiTopMat - - - ERC-2016-STG - - - 715730 - - - - - UNIVERSITAT ZURICH - UNIVERSITAT ZURICH - - - EUR 1 474 133 - - - Welfare state politics under pressure: Identifying priorities, trade-offs and reform opportunities among citizens, political and economic elites - - - EUR 1 474 133 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In times of austerity, the politics of the welfare state involve tough choices and even trade-offs: whose risks should benefit from social solidarity in a context of shrinking resources? Should the welfare state prioritize the - needs of the elderly or those of the young? Those of people in the workforce or outside of the workforce? Of natives or of immigrants? - - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Switzerland - - - WELFAREPRIORITIES - - - ERC-2016-STG - - - 716075 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 892 500 - - - Fundamentals of ASymmeTric Organo-CATalysis - - - EUR 1 892 500 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - For most biologically relevant molecules their chirality is decisive for their function. Within the last two decades asymmetric organo-catalysis has emerged as an environmental benign, metal-free alternative for conventional - asymmetric transition metal catalysis. The organo-catalysts, which employ catalyst-substrate interaction motifs commonly found for enzymes, yield unprecedented enantiomeric excesses. Despite the success of these organo-chemical routes, remarkably - little is known about the molecular details of the interaction between the catalyst and the substrate. Consequently, there is virtually no rationale method to optimize reaction conditions particularly as related to structure-function relationships. - Also the exact nature of the intermediates that induce chirality has remained elusive. The aim of this proposal is to experimentally quantify the formation of reaction intermediates and the nature of intermediate induced chirality that lie at the - heart of asymmetric control. This will be achieved by using a combination of advanced spectroscopic techniques. With advanced vibrational spectroscopies (ultrafast two-color and two-dimensional infrared spectroscopy), dielectric spectroscopy, and NMR - spectroscopy together with quantum chemical calculations we will quantify structure-dependent interactions: binding geometry, strength of attraction, lifetime of binding, reaction intermediates, and the role of steric repulsion, probed on all - timescales relevant to catalytic processes ranging from femtoseconds to seconds. Correlation of such information with the enantiomeric excess obtained in catalytic processes will allow isolating the essential ingredients for stereocontrol. Such - molecular-level insights will provide fundamental parameters for optimization of reaction conditions and will initiate the transition from a trial and error approach towards a rational design of new catalytic processes. - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - FASTO-CAT - - - ERC-2016-STG - - - 714691 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 494 963 - - - Interaction Dynamics of Bacterial Biofilms with Bacteriophages - - - EUR 1 494 963 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Biofilms are antibiotic-resistant, sessile bacterial communities that occupy most moist surfaces on Earth and represent a major mode of bacterial life. Another common feature of bacterial life is exposure to viral parasites - (termed phages), which are a dominant force in bacterial population control throughout nature. Surprisingly, almost nothing is known about the interactions between biofilm-dwelling bacteria and phages. This proposal is designed to fill this gap using - a combination of novel methodology, experimental systems, and mathematical modeling. We have recently developed a new microscopic imaging technique that allows us to image and track all individual cells and their gene expression inside biofilms. - First, we will use this technique for tracking the population dynamics of bacteria and phages within biofilms at single cell resolution. By genetically manipulating bacterial hosts and their phages, and by varying environmental conditions, we will - investigate the fundamental biological and physical determinants of phage spread within biofilm communities. Second, we will study how biofilms respond to phage attack on both intra-generational and evolutionary time scales, focusing in particular on - proximate response mechanisms and the population dynamics of phage-resistant and phage-susceptible cells as a function of biofilm spatial structure. Lastly, we will combine our novel insights to engineer phages that manipulate the composition of - biofilm communities, either by subtraction of particular bacterial species or by addition of novel phenotypes to existing biofilm community members. Altogether, the proposed research promises to uncover the major mechanistic and evolutionary elements - of biofilm-phage interactions. This combined work will greatly enrich our knowledge of microbial ecology and motivate novel strategies for bacterial biofilm control, an increasingly urgent priority in light of widespread antibiotic resistance. - - 2021-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - BIOFAGE - - - ERC-2016-STG - - - 716734 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 461 200 - - - Mapping metabolic regulators at a genome-scale to switch bacteria from growth to overproduction of chemicals - - - EUR 1 461 200 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Metabolic engineering creates improved microbes for industrial biotechnology. Rational design of industrial microbes centres on modifications of genes with known roles in the production pathway of interest. However, genes that - are unrelated to the production pathway are also known to substantially impact productivity. To date there are no methods that allow the prediction of such distal genes on a rational basis. Effects of distal genes are indirect, and mediated through - regulatory interactions between metabolites and proteins, most of which are currently unknown even in the well-studied microbe Escherichia coli. The lack of knowledge of metabolite-protein interactions thus effectively prohibits systematic - exploration of distal regulatory relationships, with the consequence that models used to predict metabolic engineering targets are severely limited and rarely applied in industrial biotechnology. Previously, we used small-scale metabolic models and - metabolomics to infer metabolite-protein interactions in specific pathways. In this project we propose a novel genome-wide endeavor to map metabolite-protein interactions across the entire metabolic network. For this purpose, we will use the recently - developed CRISPR interference system to quantitatively perturb >900 single metabolic genes in E. coli. Combining the metabolomics data of these >900 gene perturbations with a genome-scale metabolic model will enable us to infer functionally - relevant metabolite-protein interactions. Finally, we will apply this knowledge to the model-guided metabolic engineering of superior E. coli strains. Specifically, we want E. coli to cease growth upon induction and focus all its metabolic resources - towards synthesis of succinic acid. This controlled uncoupling of growth from overproduction on a rational basis will break new grounds in metabolic engineering and opens up novel applications in industrial biotechnology. - - 2021-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - MapMe - - - ERC-2016-STG - - - 715650 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 997 853 - - - Dissecting the (epi)genetic origins of phenotypic variation and metabolic disease susceptibility - - - EUR 1 997 853 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Current estimates place the prevalence of obesity beyond 1 billion by the year 2030. As a critical risk factor for heart disease, diabetes and stroke, obesity represents one of the chief socio-economic challenges of our day. - While studies have mapped a genetic framework for understanding obesity, the etiological contribution of several regulatory layers, and in particular epigenetic regulation, remain poorly understood. A perfect example, we know that isogenic C57Bl6/J - mice can vary by as much as 100% in body weight upon high fat feeding; currently, we have no mechanistic explanation for the emergence of such phenotypic variation. Here, I propose three aims dedicated towards understanding the (epi)genetic control - of phenotypic variation and disease susceptibility. First, we will catalogue epigenome and phenome variation to an unprecedented depth and resolution in the isogenic context. Next, we will examine two completely novel models of epigenetically - sensitized bi-stable obesity and thus begin a mechanistic dissection of phenotypic variation. Finally, we will map a series of gene-gene and gene-environment epistasis interactions including eight models of developmental plasticity and approximately - a dozen chromatin regulator mutants. The latter epistasis matrix will identify the molecular mechanisms that trigger, amplify and buffer phenotypic variation and stochastic obesity in mice. The functional (epi)phenomics approach is unique. It builds - the first unbiased framework against which to understand developmental plasticity and phenotypic variation, and at the same time generates powerful resources for disease researchers worldwide. - - 2021-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - DismantlingNoise - - - ERC-2015-CoG - - - 682679 - - - - - UNIVERSITAT ZURICH - UNIVERSITAT ZURICH - - - EUR 1 970 000 - - - Wiring up the SomatoSensory Cortex - - - EUR 1 970 000 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Understanding how the mammalian brain network acquires its ability during development to process information and interact with the environment is one of the fundamental challenges in modern biology. - - 2021-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Switzerland - - - InterWiring - - - ERC-2015-STG - - - 679175 - - - - - UNIVERSITAT ZURICH - UNIVERSITAT ZURICH - - - EUR 1 999 090 - - - Neuromorphic Electronic Agents: from sensory processing to autonomous cognitive behavior - - - EUR 1 999 090 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - "Neural networks and deep learning algorithms are currently achieving impressive state-of-the-art results. In parallel computational neuroscience has made tremendous progress with both theories of neural computation and with - hardware implementations of dedicated brain-inspired computing platforms. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Switzerland - - - NeuroAgents - - - ERC-2016-COG - - - 724295 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 2 250 000 - - - Development and Evolution of Colour Patterns in Danio species - - - EUR 2 250 000 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Colour patterns are prominent features of many animals and have important functions in communication such as camouflage, kin recognition and mate selection. Colour patterns are highly variable and evolve rapidly leading to - large diversities even within a single genus. As targets for natural as well as sexual selection, they are of high evolutionary significance. The zebrafish (Danio rerio), a vertebrate model organism for the study of development and disease, displays - a conspicuous pattern of alternating blue and golden stripes on the body and on the anal- and tailfins. Mutants with spectacularly altered patterns have been analysed, and novel approaches in lineage tracing have provided first insights into the - cellular and molecular basis of colour patterning. These studies revealed that the mechanisms at play are novel and of fundamental interest to the biology of pattern formation. Closely related Danio species have very divergent colour patterns in body - and fins offering the unique opportunity to study development and evolution of colour patterns in vertebrates building on the thorough analysis of one model species. Our research in zebrafish will explore the basis of direct interactions between - chromatophores mediated by channels and junctions. We will investigate the divergent mode of stripe formation in the fins and the molecular influence of the cellular environment on chromatophore interactions. In closely related Danio species, we will - investigate the cellular interactions during pattern formation. We will analyse transcriptomes and genome sequences to identify candidate genes providing the molecular basis for pigment pattern diversity. These candidate genes will be tested by - creating mutants and exchanging allelic variants using the CRISPR/Cas9 system. The work will lay the foundation to understand not only the genetic basis of variation in colour pattern formation between Danio species, but also the evolution of - biodiversity in other vertebrates. - - 2021-04-30, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - DanioPattern - - - ERC-2015-AdG - - - 694289 - - - - - UNIVERSITAT ZURICH - UNIVERSITAT ZURICH - - - EUR 1 994 981 - - - Bacterial cooperation at the individual cell level - - - EUR 1 994 981 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - All levels of life entail cooperation and conflict. Genes cooperate to build up a functional genome, which can yet be undermined by selfish genetic elements. Humans and animals cooperate to build up societies, which can yet be - subverted by cheats. There is a long-standing interest among biologists to comprehend the tug-of-war between cooperation and conflict. Recently, research on bacteria was successful in identifying key factors that can tip the balance in favour or - against cooperation. Bacteria cooperate through the formation of protective biofilms, cell-to-cell communication, and the secretion of shareable public goods. However, the advantage of bacteria being fast replicating units, easily cultivatable in - high numbers, is also their disadvantage: they are small and imperceptible, such that measures of cooperation typically rely on averaged responses across millions of cells. Thus, we still know very little about bacterial cooperation at the biological - relevant scale: the individual cell level. Here, I present research using the secretion of public goods in the opportunistic human pathogen Pseudomonas aeruginosa, to tackle this issue. I will explore new dimensions of bacterial cooperation by asking - whether bacteria engage in collective-decision making to find optimal group-level solutions; whether bacteria show division of labour to split up work efficiently; and whether bacteria can distinguish between trustworthy and cheating partners. The - proposed research will make two significant contributions. First, it will reveal whether bacteria engage in complex forms of cooperation (collective decision-making, division of labour, partner recognition), which have traditionally been associated - with higher organisms. Second, it will provide insights into the evolutionary stability of cooperation – key knowledge for designing therapies that interfere with virulence-inducing public goods in infections, and the design of stable public-good - based remediation processes. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Switzerland - - - BactInd - - - ERC-2015-CoG - - - 681295 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 2 640 632,89 - - - Electron-lattice-spin correlations and many-body phenomena in 2D semiconductors and related heterostructures - - - EUR 2 640 632,89 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Two-dimensional crystalline materials exhibit exceptional physical properties and offer fascinating potential as fundamental building blocks for future two-dimensional electronic and optoelectronic devices. Transition metal - dichalcogenides (TMDCs) are of particular interest as they show a variety of many-body phenomena and correlation effects. Key properties are: i) additional internal degrees of freedom of the electrons, described as valley pseudospin and layer - pseudospin, ii) electronic many-body effects like strongly-bound excitons and trions, and iii) electron-lattice correlations like polarons. While these phenomena represent intriguing fundamental solid state physics problems, they are of great - practical importance in view of the envisioned nanoscopic devices based on two-dimensional materials. - - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - FLATLAND - - - ERC-2015-CoG - - - 682843 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 2 350 000 - - - Genome sequences from extinct hominins - - - EUR 2 350 000 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Neandertals and Denisovans, an Asian group distantly related to Neandertals, are the closest evolutionary relatives of present-day humans. They are thus of direct relevance for understanding the origin of modern humans and how - modern humans differ from their closest relatives. We will generate genome-wide data from a large number of Neandertal and Denisovan individuals from across their geographical and temporal range as well as from other extinct hominin groups which we - may discover. This will be possible by automating highly sensitive approaches to ancient DNA extraction and DNA libraries construction that we have developed so that they can be applied to many specimens from many sites in order to identify those - that contain retrievable DNA. Whenever possible we will sequence whole genomes and in other cases use DNA capture methods to generate high-quality data from representative parts of the genome. This will allow us to study the population history of - Neandertals and Denisovans, elucidate how many times and where these extinct hominins contributed genes to present-day people, and the extent to which modern humans and archaic groups contributed genetically to Neandertals and Denisovans. By - retrieving DNA from specimens that go back to the Middle Pleistocene we will furthermore shed light on the early history and origins of Neandertals and Denisovans. - - 2021-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - 100 Archaic Genomes - - - ERC-2015-AdG - - - 694707 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 171 460,80 - - - Modelling of Generic Extreme mass-ratio inspirals - - - EUR 171 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Inspiralling binaries of compact objects are a promising source of gravitational waves (GWs) in the upcoming era of GW astronomy. The MoGEs project proposes to take the next step in modelling the evolution of compact binaries - using the gravitational self-force (GSF) formalism. Until now, the linear-in-mass-ratio GSF has only been calculated under the simplifying assumptions of non-spinning, circular, and/or equatorial binaries. MoGEs will, for the first time, calculate - linear-in-mass-ratio GSF including all effects of spin, eccentricity and inclination. - - 2019-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - MoGEs - - - H2020-MSCA-IF-2015 - - - 705229 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 195 454,80 - - - Uneven lives: female economy, migration patterns and citizenship in Early Modern Italy - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - FemEcoMig aims to study the connections between migration patterns and female property, work and social networks in Early Modern Italy: it focuses on domestic and international migrations and on female migrants (and their - families) who moved to the duchy of Savoy-Piedmont during the period 1650-1800. The project aims to change the common narrative on the history of migration by bringing into the topic a range of historiographical problems that are often considered - characteristic of the history of women. It will inquire into the role women's paid and unpaid work and into the use of female property in settlement paths; it will also tackle the extent of female social networks and their use to access to urban - resources. The second objective is to analyse the connections between female migration and the achievement of naturalisation. This section will investigates foreign women applying for naturalisation and the reasons for their application. The project - will tackle the contents of the grant, and the conditions in which citizenship was enacted and will inquire into the links between migration and settlement paths, economic activities and family strategies. - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - FemEcoMig - - - H2020-MSCA-IF-2015 - - - 703737 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 2 498 013 - - - Rules of self-organization and reengineering of liver tissue - - - EUR 2 498 013 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - We want to understand the rules of self-organization underlying tissue structure and function. To address this problem, we have chosen the mouse liver with its complex apico-basal polarity of hepatocytes and its unique 3D - tissue organization. We aim at identifying the rules of self-organization of liver tissue and their implementation at the molecular level. Our ultimate goal is to demonstrate that it is possible to reengineer liver tissue structure. The first aim - will be to develop a digital geometrical model of liver tissue, i.e. an accurate 3D digital representation of the cells, forming the tissue and their sub-cellular components, in the developing, adult and regenerating liver, and unravel the principles - for how the cells are organized to generate liver cell architecture. In aims 2 and 3, we will identify the molecular mechanisms underlying such geometrical rules. In particular, the second aim will be to characterize the molecular mechanisms - responsible for hepatocyte cell polarity and predictably modify cell organization in vitro. The third aim will consist of introducing genetic perturbations to alter hepatocyte cell organization (cell polarity) and cell-cell interactions to - predictably modify the structure and function of liver tissue. The fourth aim will be to develop a physical model of liver tissue self-assembly and organization. The project is ambitious as it aims to understand the rules of tissue organization in 3D - in a mammalian organ to such an extent that it is possible to make predictions of tissue response to genetic perturbations and reengineer it to modify its structural and functional properties. - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - RULLIVER - - - ERC-2015-AdG - - - 695646 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 2 500 000 - - - Blood Vessel Development and Homeostasis: Identification and Functional Analysis of Genetic Modifiers - - - EUR 2 500 000 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - The vascular system is a complex network of blood vessels that transports gases, nutrients and hormones throughout the organism. Most blood vessels that form during development and growth arise by the sprouting of new - capillaries from pre-existing vessels, a process termed angiogenesis. An imbalance in angiogenesis contributes to the pathogenesis of numerous disease states: insufficient angiogenesis limits tissue recovery in ischemic disease, whereas stimulation - of angiogenesis by cancer cells promotes tumor vascularization and growth. Angiogenesis inhibitors are already in clinical use for anti-tumor therapy; however, multiple reports of resistance are calling for the identification of additional targets. - Furthermore, vascular malformations are a significant cause of morbidity and mortality. While the genetic basis for some vascular malformations is known, many genetic factors, including modifiers that affect the age-of-onset and severity of - phenotypes, remain to be identified. Identifying modifier genes is important not only to fully assess genetic risk, but also to provide novel targets for therapy; however, identifying modifier genes has proven challenging. We recently uncovered a - novel and simple way to identify modifier genes. By investigating gene and protein expression differences between knockout (mutant) and knockdown (antisense treated) zebrafish embryos, we found that mutations in specific genes, including some - encoding angiogenic factors, lead to the upregulation of compensating (i.e., modifier) genes while knocking down these same genes does not. We hypothesize that the modifier genes identified through this approach in zebrafish also play important roles - in humans. Thus, we will use this simple strategy to identify new genes that regulate vascular formation and homeostasis, and subsequently analyze their function in zebrafish as well as in mammalian models, as they are likely to play key roles in - vascular development and disease. - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - ZMOD - - - ERC-2015-AdG - - - 694455 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 2 495 000 - - - Physics of Star Formation and Its Regulation - - - EUR 2 495 000 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - In the past decade we learned when and where stellar mass was built up in galaxies through cosmic time, now we must understand the physical causes in order to answer `How do galaxies form and evolve?’. This ERC project is - designed to greatly advance our understanding of the physics of the star formation (SF) process and its regulation in typical star forming galaxies. The ERC project consists of 2 complementary parts: (A) an unparalleled characterization of the SF - process in nearby galaxies through full exploitation of the revolutionary capabilities of the latest millimeter interferometers (ALMA) and optical integral field units (MUSE). This study will constrain the key physical parameters for the SF process - on only 50pc scales - the scale of large HII regions and their predecessors, giant molecular clouds. At this crucial scale, the MUSE-ALMA-HST Survey will provide a characterization of the SF history, stellar/gaseous surface densities, metallicities - of stars and gas, the stellar radiation field, extinction, and stellar/gas kinematics, and thus uncover the physical conditions that control and regulate the SF process. Part (B) will place the results of part (A) in a cosmological context, by - characterizing key galaxy quantities (e.g., gas mass fraction, specific SF rates, gas depletion times) in fully representative galaxy samples after (z<3) and before (z>3) the peak epoch of cosmic star formation density. In addition to providing - the critically needed constraints on the conditions that govern the SF process, this ERC project will provide the observational benchmark for state-of-the art galaxy simulations and models. The PI is internationally recognized as a leader in SF - studies in nearby and distant galaxies, and has successfully led large international collaborations that strongly shaped our current understanding of the SF process. Through her track record and access to the required data, the PI is uniquely - positioned to successful lead this ambitious program. - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - PhysSF - - - ERC-2015-AdG - - - 694343 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 2 469 136 - - - Absolute Spin Dynamics in Quantum Materials - - - EUR 2 469 136 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - One of the greatest challenges in exploiting the electron spin for information processing is that it is not a conserved quantity like the electron charge. In addition, spin lifetimes are rather short and correspondingly - coherence is quickly lost. This challenge culminates in the coherent manipulation and detection of information from a single spin. Except in a few special systems, so far, single spins cannot be manipulated coherently on the atomic scale, while spin - coherence times can only be measured on spin ensembles. A new concept is needed for coherence measurements on arbitrary single spins. Here, the principal investigator (PI) will combine a novel time- and spin-resolved low-temperature scanning - tunneling microscope (STM) with the concept of pulsed electron paramagnetic resonance. With this unique and innovative setup, he will be able to address long-standing problems, such as relaxation and coherence times of arbitrary single spin systems - on the atomic scale as well as individual spin interactions with the immediate surroundings. Spin readout will be realized through the detection of the absolute spin polarization in the tunneling current by a superconducting tip based on the - Meservey-Tedrow-Fulde effect, which the PI has recently demonstrated for the first time in STM. For the coherent excitation, a specially designed pulsed GHz light source will be implemented. The goal is to better understand the spin dynamics and - coherence times of single spin systems as well as the spin interactions involved in the decay mechanisms. This will have direct impact on the feasibility of quantum spin information processing with single spin systems on different decoupling surfaces - and their scalability at the atomic level. A successful demonstration will enhance the detection limit of spins by several orders of magnitude and fill important missing links in the understanding of spin dynamics and quantum computing with single - spins. - - 2021-06-30, ongoing project - - - 2016-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - ABSOLUTESPIN - - - ERC-2015-CoG - - - 681164 - - - - - UNIVERSITAT ZURICH - UNIVERSITAT ZURICH - - - EUR 1 700 000 - - - Developing multi-modality nanomedicines for targeted annotation of oncogenic signaling pathways - - - EUR 1 700 000 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Spatial and temporal changes in the underlying biochemistry of cancer control disease progression and response/resistance to treatment. Developing methods to detect changes in oncogenic signaling at an early stage is vital to - further our understanding of cancer, and will advance the next generation of anti-cancer therapies. Nanomedicine is the medical application of nanotechnology to diagnose or treat disease. In light of the recent introduction of tools like Positron - Emission Tomography/Magnetic Resonance Imaging (PET/MRI) scanners, there is now a new opportunity to develop hybrid imaging protocols that can simultaneously take advantage of the functional and anatomic information available from PET/MRI to address - changes in oncogenic signaling pathways. The work outlined in this interdisciplinary ERC Project is designed to advance new chemistry and imaging methods to measure changes in oncogenic signaling in various cancers before, during and after treatment - using PET/MRI. The long-term goals are to expand the scope and utility of radiolabelled nanomedicines as dual-modality PET/MRI probes for detecting changes in oncogenic signaling in various cancers and develop efficient methods for translating new - technologies to the clinic. Successful completion of this ERC Project has the potential to transform personalised clinical management of cancer patients via advanced PET/MRI detection of oncogenic signaling processes. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Switzerland - - - NanoSCAN - - - ERC-2015-STG - - - 676904 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 500 000 - - - Mechanisms of Regeneration Initiation - - - EUR 1 500 000 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Injury poses a key threat to all multicellular organisms. However, while some animals can fully restore lost body parts, others can only prevent further damage by mere wound healing. Which molecular mechanisms determine - whether regeneration is induced or not is an unsettled fundamental question. I will use whole body regeneration, one of the most fascinating biological processes, as an experimental paradigm to identify the mechanisms of regeneration initiation. As a - model organism I will employ planarians, flatworms with extraordinary plasticity that regenerate every piece of their body within a few days. I will mechanistically dissect how these animals rapidly induce an efficient regeneration program in - response to tissue loss and define the key switches that determine whether a wound regenerates. Combining the astonishing regenerative abilities of planarians with new technologies I will first comprehensively describe the molecular changes occurring - during the amputation response. Second, with a powerful novel assay developed in my lab - dormant fragments - that allows for the first time the separation of wounding from tissue loss in a single planarian, I will analyze the dynamics of the - earliest regenerative events. Third, I will functionally characterize the regeneration-initiating signals and their target pathways combining in vivo RNAi and phenotypic assays. Fourth, with a regeneration-deficient planarian species, I will test - whether the identified key regulators act as network nodes that can be utilized to rescue regeneration. Importantly, using the regenerating zebrafish fin as an experimental paradigm I will investigate conserved roles of these network nodes and - validate general principles of regeneration initiation. This project will not only uncover conserved mechanisms of regeneration initiation but will also identify the switches that must be levered to induce regeneration in non-regenerating animals. - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - IniReg - - - ERC-2016-STG - - - 716894 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 2 181 250 - - - Small - and nano - scale soft phononics - - - EUR 2 181 250 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Colloid and polymer science allows the engineering of acoustic and optical material functionalities of hierarchical structures on various length scales commensurate with and well below the characteristic length scales of - phonons and photons. Periodic structures act as both hypersonic phononic and visible light photonic crystals (phoxonics). We recently extended the decade-old field to hypersonic phononics. Many important questions in this young field are just being - raised and require new conceptual and technical approaches to address them. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - Smartphon - - - ERC-2015-AdG - - - 694977 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 2 496 250 - - - Structural biology of mammalian transcription regulation - - - EUR 2 496 250 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - The regulation of gene transcription by RNA polymerase (Pol) II underlies cell differentiation and organism development, and its dysregulation causes many cancers. Transcription regulation occurs during initiation, when Pol II - assembles with initiation factors on promoter DNA, but also during mRNA chain elongation, when Pol II pauses near the promoter before it restarts upon activation. Our previous ERC Advanced Grant ‘TRANSIT’ enabled us to provide molecular insights into - yeast Pol II initiation and its regulation by the Mediator coactivator complex (Plaschka et al., Nature 2015; Sainsbury et al., Nature 2012, Lariviere et al, Nature 2012). Here, with our new proposal ‘TRANSREGULON’ we wish to open a new frontier and - provide the structural basis for mammalian Pol II regulation during elongation. We will use an integrated structural biology approach combining X-ray crystallography, cryo-electron microscopy, and crosslinking, to obtain the first atomic structure of - a mammalian Pol II enzyme (aim 1), the structure of the negative elongation factor NELF (aim 2), which is required for promoter-proximal pausing by mammalian Pol II, and the threedimensional architecture of the promoter-proximally paused Pol II - complex (aim 3) containing the multiprotein pausing factors NELF and DSIF, and eventually also the pause release factor p-TEFb. This ground-breaking work will make the transition from yeast to human structural biology of transcription, will provide - the molecular basis for a central mechanism of cellular regulation, and will advance structural biology methods for dissecting large and transient mammalian multicomponent complexes. - - 2021-06-30, ongoing project - - - 2016-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - TRANSREGULON - - - ERC-2015-AdG - - - 693023 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 505 000 - - - Imaging synaptic plasticity by ultra-high field magnetic resonance spectroscopy in health and psychiatric disease - - - EUR 1 505 000 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - A large number of psychiatric disorders (major and bipolar depression (MDD / BD), schizophrenia, obsessive-compulsive disorder (OCD), addiction, anxiety, attention deficit hyperactivity syndrome (ADHS), posttraumatic stress - disorder (PTSD), autism) lack objective criteria for primary diagnosis, early differential diagnosis with regard to subtypes in treatment response and disease progression or effective therapy monitoring. Hence, the search for relevant biomarkers is - of high importance. This proposal suggests the development of novel methodology for highly spatially and temporally resolved imaging of disease effects on neurotransmission, membrane processes related to synaptic plasticity and brain energy - metabolism in psychiatric disorders and the acute and chronic impact of related pharmacological treatment in the human brain. To that, the advantages of a unique 9.4 T whole body human magnetic resonance imaging (MRI) system for 1H, 31P and 13C - magnetic resonance spectroscopic imaging shall be exploited. Highly innovative enabling MRI technology including parallel transmission, very high order B0 shimming, a real time field stabilization and motion correction approach along with the - principles of advanced encoding and non-Fourier image reconstruction shall ensure high data quality. Next to obtaining 20 novel image contrasts based on steady state metabolite concentrations, the ultimate goal of the proposed research is to enable - functional spectroscopic imaging in the entire human brain in order to investigate adaptation of neurotransmission and brain metabolism to environmental stimuli as well as the impact of acute pharmacological intervention. Finally, the spatially and - temporally resolved metabolic imaging technology shall be used for investigation of patients with major depressive disorder to reveal novel biomarkers relevant for diagnostics and patient stratification. - - 2021-06-30, ongoing project - - - 2016-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - SYNAPLAST MR - - - ERC-2015-STG - - - 679927 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 159 460,80 - - - Understanding the molecular basis of stochastic bi-stable obesity - - - EUR 159 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Substantial evidence indicates that even when genetically matched, we are not created equal. The mechanisms underlying such non-Mendelian phenotype variation are sufficient to elicit complex disease but remain unknown. - - - 2018-11-30, ongoing project - - - 2016-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - EPOC - - - H2020-MSCA-IF-2015 - - - 707123 - - - - - UNIVERSITAT ZURICH - UNIVERSITAT ZURICH - INILABS GMBH - - - EUR 150 000 - - - Embedded Neuromorphic Sensory Processor - - - EUR 150 000 - - - Switzerland - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Neuromorphic computing has demonstrated high potential for creating computing systems with order-of-magnitude improvements in energy efficiency and robustness to noisy or unreliable sensory signals, such as those inherent in - vision. However, a significant roadblock to realizing the full potential of this emerging brain-inspired technology is the current practical need to use inefficient and slow (high latency) legacy von Neumann architectures to convert the input data - that needs to be processed, and supply it to the neuromorphic system for further processing. - - - 2017-11-30, closed project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2015 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Switzerland - - - NeuroPsense - - - ERC-2015-PoC - - - 713736 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 239 860,80 - - - Attention and memory components in every-day cognitive problems in aging - - - EUR 239 860,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Older individuals experience problems in many every-day tasks, due to age-related decline in cognitive functions. Cognitive frailty is a societal and economical challenge, as it affects elderly’s quality of life and need for - care. To understand, and counteract, cognitive difficulties, we need to be able to measure them. Basic research has revealed essential knowledge on age-related cognitive and neuronal changes. However, the correlation between laboratory task - performance, brain alterations, and experienced difficulties in daily life is imperfect. In the realms of attention and memory, the problem may lie in the tasks we use. Most laboratory tasks are made of brief trial structures, which is useful to - isolate specific process components. Real world tasks, while built of smaller components, are complex and extend over time. This project presents a multi-method neuro-cognitive approach to unravel sources of older individuals’ deficit. The research - is based on leading theoretical models and includes behavioral data modeling, eye-movement and EEG data analyses. At my TC host, Wolfe’s Visual Attention Lab (Harvard Medical School), we will create new extended hybrid search and foraging tasks that - enable us not only to look at the small components, but also to analyze how they interact over time, and how they relate to age-specific daily problems. At Bundesen’s Center for Visual Cognition (University of Copenhagen), the new knowledge will be - integrated into the computational “Theory of Visual Attention” framework and the model-based assessment procedure. Our aim is to advance the theoretical knowledge about attention and memory and improve cognitive assessment products. Commercialization - of the newly developed tests will be exploited together with the industrial partner Cambridge Cognition, a company producing cognitive assessment tools. The outcome will be relevant to the development of technology, products, and strategies to meet - the needs of our aging population. - - 2020-02-29, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Germany - - - MEMORAGE - - - H2020-MSCA-IF-2015 - - - 702483 - - - - - THE UNIVERSITY OF EDINBURGH - THE UNIVERSITY OF EDINBURGH - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 2 499 331 - - - An integrated approach to understanding the impact of de novo mutations on the mammalian genome - - - EUR 2 499 331 - - - United Kingdom - United Kingdom - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Understanding the process of spontaneous mutation is fundamental for understanding the genetic basis of quantitative variation, the threat posed by declining population size in conservation biology and the distribution of - nucleotide variation in the genome. I will address these and other unanswered questions concerning the evolutionary impact of spontaneous mutation using the house mouse as a model system. With the first, highly replicated mutation accumulation (MA) - experiment in any vertebrate, I will study the impact of mutation accumulation on fitness and other quantitative traits and on genomic variation. I will pay particular attention to the effects of mutations in the heterozygous state, since this is - important for resolving two important questions: 1. The threat posed by deleterious mutation accumulation in humans, where natural selection has weakened in many populations, and in endangered species, where declining effective population size has - made selection less effective, and 2. The extent by which new mutations sustain response to artificial selection. By characterizing many thousands of mutation events by genome sequencing of MA lines and wild mice, I will determine the molecular - spectrum and the factors explaining mutation rate variation across the genome. I will exploit this new knowledge to address the long-unanswered question of the causes of correlations between nucleotide diversity and the recombination rate and the - density of conserved genomic elements. I will develop new approaches, incorporating the simultaneous action of mutation, selection, drift and recombination, to determine the contributions of background selection and selective sweeps to variation in - nucleotide diversity, and to quantify the contributions of coding and noncoding mutations to fitness variation. - - - 2021-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - DENOVOMUT - - - ERC-2015-AdG - - - 694212 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 330 625 - - - Gravity, Inflation, and Galaxies: Fundamental Physics with Large-Scale Structure - - - EUR 1 330 625 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Over the past two decades, a data-driven revolution has occurred in our understanding of the origin and evolution of our Universe and the structure within it. During this period, cosmology has evolved from a speculative branch - of theoretical physics into precision science at the intersection of gravity, particle- and astrophysics. Despite all we have learned, we still do not understand why the Universe accelerates, and how the structure in the Universe originated. Recent - breakthrough research, with leading contributions by the PI of this proposal, has shown that we can make progress on these questions using observations of the large-scale structure and its tracers, galaxies. This opens up a fascinating, new - interdisciplinary research field: probing Gravity and Inflation with Galaxies. The goal of the proposed research is to first, probe our theory of gravity, General Relativity, on cosmological scales. Second, it aims to shed light on the origin of the - initial seed fluctuations out of which all structure in the Universe formed, by constraining the physics and energy scale of inflation. While seemingly unrelated, the main challenge in both research directions consists in understanding the nonlinear - physics of structure formation, which is dominated by gravity on scales larger than a few Mpc. By making progress in this understanding, we can unlock a rich trove of information on fundamental physics from large-scale structure. The research goals - will be pursued on all three fronts of analytical theory, numerical simulations, and confrontation with data. With space missions, such as Planck and Euclid, as well as ground-based surveys delivering data sets of unprecedented size and quality at - this very moment, the proposed research is especially timely. It will make key contributions towards maximizing the science output of these experiments, deepen our understanding of the laws of physics, and uncover our cosmological origins. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - GrInflaGal - - - ERC-2015-STG - - - 678652 - - - - - UNIVERSITAT ZURICH - UNIVERSITAT ZURICH - - - EUR 1 499 755 - - - How Infection History Shapes the Immune System: Pathogen-induced Changes in Regulatory T Cells - - - EUR 1 499 755 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Studying host-pathogen interactions by focusing on the interaction of a single pathogen with the host has defined our understanding of these events and the insights gained form the basis for the therapeutic and vaccination - strategies we use today. However, people become infected with multiple pathogens throughout their lifetime, at times even simultaneously. Still, it is largely unknown how the immune response to one pathogen alters the body’s ability to respond to a - second infectious agent or the susceptibility to autoimmunity or cancer. This project will address this question by focusing on infection-induced changes in regulatory T cells (Tregs) as they may lead to biased suppression and changes in the nature - of subsequent immune responses. - - 2021-05-31, ongoing project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Switzerland - - - Immune Regulation - - - ERC-2015-STG - - - 677200 - - - - - UNIVERSITAT ZURICH - - - EUR 187 419,60 - - - The role of the iron-sulpur cluster in human DNA polymerase delta - - - EUR 187 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - The human genome is composed of 3 billion base pairs of DNA that are replicated prior to every cell division with an astonishing accuracy. High-fidelity replication is necessary to maintain genome stability, and hence to avoid - premature ageing and cancer. This project aims at understanding the role of the iron-sulphur (FeS) cluster in human DNA polymerase delta (Pol δ), one of the major replicases. - - 2018-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - TRISCPOL - - - H2020-MSCA-IF-2015 - - - 707299 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 239 860,80 - - - REciprocal LOcal ADapatation: the genetic, behavioural and chemical study of the evolutionary maintenance of a mutualism - - - EUR 239 860,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - The goal of this research is to identify and characterize genetic, behavioural and biochemical mechanisms underlying reciprocal local adaptation between partners in a complex mutualism. It will focus on a unique and - outstanding model system found in the New World tropics: the “devil’s gardens” created by the ant, Myrmelachista schumanni, whose workers systematically attack and kill seedlings of foreign plants that germinate too close to their host plants. This - cultivation behaviour results in low diversity, orchard-like stands of their host plants in the middle of some of the most diverse rainforests on earth. This project will bring together researchers from Harvard University and the Max Planck Institute - to address three main questions through a combination of newly developed genome sequencing techniques, large-scale field-ecology behavioural experiments and state-of-the-art chemical analyses: (1) Do Myrmelachista schumanni and its host plants - reciprocally influence each other’s population sizes, level of gene flow and genetic structure? (2) How specialized are interactions between Myrmelachista schumanni and the several species of plants that it cultivates? (3) What are some of the - proximate mechanisms underlying host specificity, and in particular, can ants recognize different plant species and if so, how? In carrying out this research, postdoctoral fellow Pierre-Jean Malé will expand his expertise by gaining training in - phylogenomics and chemical ecology. The project, referred to here as "RELOAD" (forREciprocal LOcal ADaptations), will also enable him to broaden the ecological and evolutionary scale of his research, and enhance his long-term goal of obtaining a - faculty position at a European university and/or research institution. - - 2019-06-30, ongoing project - - - 2016-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Germany - - - RELOAD - - - H2020-MSCA-IF-2015 - - - 705846 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 159 460,80 - - - The impact of TFIID on the transcription initiation machinery – a structural perspective. - - - EUR 159 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Transcription is a first step of gene expression, a process by which a functional gene product is synthesized based on genetic information from DNA. Gene expression is tightly regulated with complex mechanisms that give cells - the flexibility to adapt to a variable environment. Defects in regulation and transcription mechanisms leads to serious pathologies in cells and organisms, that in humans includes cancer development, autoimmunity and neurological disorders, - cardiovascular diseases etc. - - - 2018-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - POL2-TFIID - - - H2020-MSCA-IF-2015 - - - 708500 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 2 418 750 - - - Solar magnetic field and its influence on solar variability and activity - - - EUR 2 418 750 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - For life on Earth, the Sun is the most important astrophysical object in the universe. For astrophysicists, the atmosphere of the Sun presents an intriguing, complex and extremely varied environment generated by continuous - dynamic, small-scale interactions between plasma and intricately structured magnetic fields. - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - SOLMAG - - - ERC-2015-AdG - - - 695075 - - - - - UNIVERSITAT ZURICH - - - EUR 175 419,60 - - - A novel approach for detecting polygenic adaptation applied to FORest tree candidate GEne NETworks - - - EUR 175 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - Unravelling the mechanisms of selection that allow species to adapt to changing environments has been a perpetual goal of evolutionary genetics. A current paradigm shift seems to radically change our view regarding the major - mechanisms of evolutionary change. Ample experimental data indicates that most traits that potentially play a role in adaptations are controlled by many genes that may not act independently, but as members of complex gene interaction networks. Thus, - it is widely agreed that most adaptation events in natural populations are reached via so-called polygenic adaptation, involving small changes at multiple genes at a time. Nevertheless, methods are still lacking to detect such adaptive gene - associations. The main objective of FORGENET is to propose NetAdapt, a network-based test of polygenic selection for candidate-gene data. NetAdapt exploits candidate-gene data both as genotype and functional genomic data. First, based on the - functional genomic information inherent to candidate gene data, it proposes to construct a gene interaction network, whose topology can be used to define a null hypothesis of neutrality. Second, based on the genotype data, it proposes a test for - detecting selection on gene interactions, i.e. epistatic selection, based on linkage disequilibrium statistics. NetAdapt is expected to enhance our understanding how selection acts on gene networks and to propose new candidate genes for future - genotyping. NetAdapt will be applied to published data on coniferous forest trees that have been genotyped from haploid tissue, which offers a straightforward application. Many conifers are endangered by climate change and estimating their - adaptability is an important European research priority. FORGENET will study the evolution of flowering time genes at spruces along latitudinal gradients, and drought tolerance in Mediterranean pine species. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - FORGENET - - - H2020-MSCA-IF-2015 - - - 705972 - - - - - UNIVERSITAT ZURICH - - - EUR 175 419,60 - - - Systematic profiling of molecular changes during prion disease progression - - - EUR 175 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - Prion diseases are fatal neurodegenerative diseases and are caused by proteinaceous infectious particles termed prions. The infectious agent of prion diseases has been identified decades ago, but the actual cellular processes - that subsequently cause neurons to degenerate remain poorly understood. - - - 2018-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - Prionomics - - - H2020-MSCA-IF-2015 - - - 706138 - - - - - UNIVERSITAT ZURICH - - - EUR 175 419,60 - - - Beyond double-strand break repair: specific mechanisms of homologous recombination at stressed replication forks. - - - EUR 175 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - Genomic instability is the main driving force of tumourigenesis, as highlighted by the cancer predisposition conferred by mutations in caretaker genes. DNA replication stress has recently received much attention, for its - causative role in transformation and as a strategy for cancer therapy. Besides other mechanisms protecting replicating chromosomes from genotoxic stress, transient fork remodelling into four-way junctions (fork reversal) is emerging as a key - transaction to assist template repair or to tolerate DNA damage and replication interference. Factors and mechanisms modulating this transaction are just beginning to emerge. The central recombinase RAD51 was recently shown to promote fork reversal, - uncovering a fork-specific role for homologous recombination (HR) proteins, beyond their established role in the double-strand break repair. However, the molecular determinants controlling RAD51-mediated fork remodelling are yet unknown. I propose to - gain mechanistic insight into the role of RAD51 and other HR proteins in replication stress, using an integrated, multidisciplinary approach, which combines my current biochemical expertise with specialized cell biology and single-molecule techniques - available in the host lab. In particular, I will first set up a microscopy-based screen to identify factors that regulate RAD51 recruitment at replication forks upon stress. Then, I will use a combination of single-molecule and cell biology - techniques to investigate how these novel RAD51 regulators mediate in vivo RAD51 role in fork protection and remodelling. Finally, I will establish an in vitro system to study biochemically the mechanisms by which RAD51 and the novel identified - factors catalyse replication fork remodelling. I believe that this "holistic" approach will be instrumental not only to define the molecular basis of cancers with a HR-defective genetic background, but also to provide the groundwork to develop more - effective chemotherapeutic strategies. - - 2018-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - RecInRep - - - H2020-MSCA-IF-2015 - - - 704817 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 181 002,60 - - - Discrete Dirac Mechanics and Geometric Numerical Integration Methods for Plasma Physics - - - EUR 181 002,60 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - In recent years it has been realised that the preservation of certain structures and properties of mathematical equations is of utmost importance when bringing them in a form understandable by computers. Ignoring such - properties often leads to incorrect results in the corresponding simulations. In plasma and fusion physics this is especially true as the mathematical equations are highly complex and direct comparison with the experiments is very difficult. Still, - the application of structure-preserving numerical algorithms to plasma physics has not gained much attention and todays computer codes do not use such methods. Consequently, these codes are not able to reproduce important physical effects observed in - the experiments, hindering progress in research. - - 2018-03-31, ongoing project | - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Germany - - - DDM-GNI - - - H2020-MSCA-IF-2015 - - - 708124 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 171 460,80 - - - Synthetic Mimicry of Cellular Polarisation - - - EUR 171 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Biological self-organisation through spontaneous symmetry breaking is essential for the emergence and maintenance of life. Cell polarity, where an asymmetric distribution of molecules is achieved within a cellular compartment, - is one of the simplest and most studied examples. However, due to the diversity and complexity of nature, and despite the many known pathways and theoretical models, the fundamental mechanisms are still poorly understood. I propose a ‘bottom-up’ - synthetic biology approach to build a synthetic system capable of mimicking cellular polarisation in an artificial compartment. Modular fusion proteins will be engineered from small, well-characterised protein domains and reconstituted into - artificial membrane-bound compartments such as Giant Unilamellar Vesicles (GUVs) and microfluidic water-in-oil droplets. The self-organisation of these proteins through autocatalytic membrane-recruitment will be monitored with a variety of - fluorescence microscopy techniques. In doing so, I will create a minimal, defined system in which to test general principles of biological self-organisation, abstracted from the ‘noise’ of natural systems. Further, orthogonal synthetic systems could - be introduced into living organisms to control morphology and other functions, or be used to build higher-level mimics of life such as proto-cells. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - POLAR - - - H2020-MSCA-IF-2015 - - - 705587 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 159 460,80 - - - Flame retardant Nanocontainers - - - EUR 159 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Since we live in the polymer age, and polymers are highly inflammable, flame retardants have become a key component in industry to reduce the impact of fires. Flame retardants save people's lives, their property and in some - cases even the environment. However, traditional flame retardants like halogenated compounds present some serious disadvantages, like environmental persistence and toxicity, and their use is currently limited by REACH (EC 1907/2006). Halogen-free - flame retardants like organophosphorus compounds or metal hydroxides, on the other hand, deteriorate the mechanical properties and have poor effectiveness. In this area, nanotechnology provides us some badly needed new approaches. In NOFLAME, we will - explore a new approach based on the development of polymer flame retardant nanocontainers with high thermal stability, low flammability and good compatibility with polymeric matrices. These nanocontainers will help solve the problems of poor - dispersion and low interfacial adhesion of the inorganic and hybrid nanomaterials applied so far. Furthermore, the ability to encapsulate a wide range of substances makes them highly attractive to develop multifunctional nanomaterials. The main - activities within NOFLAME are: 1) the synthesis of several nanocontainers and the encapsulation of organic and inorganic flame retardant compounds, 2) the introduction of the nanocontainers in the polymer matrix and 3) the evaluation of their - influence on the mechanical and flame retardant properties of the final material. Combining their expertise for NOFLAME, the fellow Dr. Maria Velencoso, the host MPIP and the partner BAM will execute a thrilling research project to produce novel - flame retardant nanomaterials and meet an urgent need of the European plastics industry. - - 2018-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - NOFLAME - - - H2020-MSCA-IF-2015 - - - 705054 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 171 460,80 - - - Elucidating the Mechanisms of Insect’s Chemical Taste to Understand Specific Host-Plant Selection - - - EUR 171 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - The sense of taste enables an animal to decide what it eats and drinks. Insects are able to discriminate among soluble chemicals via their gustatory receptors (GRs) in order to accept or reject a certain food plant or initiate - mating and oviposition. Despite their essential role in the insect’s overall food intake, survival and reproductive success, relatively little is known about insect GRs, especially in beetles. This is surprising given their importance as agricultural - and forestry pests, their global distribution and huge species number as herbivorous insects. I aim to identify and characterise GRs that mediate host plant selection in a specialist poplar leaf beetle, Chrysomela populi. These beetles feed on - economically important poplar trees and damage timber plantations worldwide. It is hypothesised that the phenolic glucoside salicin in poplar is a major taste stimulant for C. populi and enhances feeding activity. However, it is unknown how salicin - or, alternatively, other taste stimulants are detected by, and interact with specific GRs in C. populi to elicit feeding behaviour. I will elucidate these mechanisms by (i) identification of candidate genes encoding GRs in C. populi via tissue - specific transcriptome sequencing and transcript visualisation via RNA-FISH, (ii) knock-down of single GR genes via RNAi to test the feeding behaviour of RNAi-silenced beetles, and (iii) test whether any of the taste stimulants from poplar function - as in vivo and in vitro ligand for specific C. populi GRs by tissue-specific electrophysiological recordings and heterologous expression, respectively. These results will shed new light on the question how GRs function as regulators for herbivorous - beetles to select and consume specific plants, which will significantly advance our knowledge in understanding host plant selection. As poplar leaf beetles are important pests, the results may also pave the way for timely development of sustainable - pest management in forestry. - - 2018-11-30, ongoing project - - - 2016-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - ChemoSense - - - H2020-MSCA-IF-2015 - - - 705151 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 171 460,80 - - - Defining the genetics of grapheme-colour synaesthesia - - - EUR 171 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Synaesthesia is a common neurodevelopmental phenomenon (2-5% of the population) where stimulation of one sense automatically triggers an experience of another. Familial clustering indicates that synaesthesia is highly - heritable. However, this genetic contribution is poorly understood and likely heterogeneous, a major hindrance to our understanding of the neurobiology. My objective is to remove this barrier through the most comprehensive interrogation of - synaesthesia genetics to date, utilizing state-of-the-art technologies and integrative approaches. - - 2018-05-31, ongoing project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - SynGenes - - - H2020-MSCA-IF-2015 - - - 704393 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 159 460,80 - - - Chromatin targeting and remodelling by bacterial effectors in plant immunity - - - EUR 159 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - In nature, plants are challenged by disease-causing pathogens such as viruses, bacteria and fungi. Understanding mechanisms of plant disease and disease resistance is of fundamental importance to sustainable agriculture and - human health. Unlike mammals, plants lack a circulating immune system. Plants instead rely on the innate immune capacity of each cell and systemic signals that disseminate from infection sites. Successful pathogens use effectors to suppress plant - immunity and cause disease. Plants have evolved disease resistance genes encoding immune receptors that perceive specific pathogen effectors to mount effector-triggered immunity. In Arabidopsis, a heteromeric pair of intracellular immune receptors - forms a functional recognition complex which senses virulence activities of two structurally unrelated bacterial effectors at the nuclear chromatin. Results suggest that effector targeting of histone modifications and chromatin remodelling interferes - with host basal immunity and that this is transduced by the receptor pair to activation of defence pathways. The underlying molecular mechanisms remain unclear. We have found that the two bacterial effectors interact with an overlapping set of - chromatin-associated proteins and with certain immune receptor domains. We hypothesize that the effectors converge on the same chromatin machinery for promoting disease and that their actions are intercepted by the immune receptor system which is - physically connected to basal immunity signalling components. By using the effectors as molecular probes, this proposal aims to elucidate how the chromatin environment is modulated during infection and how effector perturbations are converted to - effective immunity. - - 2018-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - CHERI - - - H2020-MSCA-IF-2015 - - - 705631 - - - - - STICHTING WAGENINGEN RESEARCH - - - EUR 165 598,80 - - - Development of an in vitro cellular model to predict the immunological impact of dietary proteins - - - EUR 165 598,80 - - - Netherlands - - - Research Organisations - - As the world population continues to grow and a shortage of protein supply is foreseen, there is a need to identify new and sustainable protein sources. While these alternative proteins must be of high nutritional quality, - they also need to be safe for consumption. Dietary proteins and their digestion products can influence a number of regulatory systems, including the immune system. By interacting with elements of the immune system, proteins can help balance and - stabilize immune responses, but may also trigger adverse effects such as allergic reactions. While the effects of proteins and peptides on the adaptive immunity have been examined in a number of studies, few have studied how these molecules are - absorbed through the small intestine and interact with the innate immune system. Since, in order to trigger an immune response proteins must first be transported across the intestinal wall and interact with the innate immune system, understanding - these processes is key to determining the immunological effects of protein consumption. The aim of the proposed project is to develop an in vitro model to evaluate the impact of dietary proteins on the immune system. This research will first examine - the uptake of proteins and their digests across the intestinal wall using cellular models mimicking the intestinal epithelium and subsequently investigate the effect of the absorbed proteins/peptides on the immune system’s key players, including the - dendritic and T cells. The model system that this research aims to develop could help shed light on the roles played by dietary proteins in regulating intestinal immunity and serve as a tool to evaluate the immunological properties of novel and - sustainable proteins. Thus, this research is of relevance not only to the European food industry, but also to public health. - - 2018-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - IVSysImmunoProt - - - H2020-MSCA-IF-2015 - - - 703929 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 159 460,80 - - - Reconstitution of the basic molecular mechanism of phagocytosis – a bottom-up synthetic biology approach - - - EUR 159 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - The ability of cells to engulf large objects, such as invading microorganisms or apoptotic cells, is crucial to innate immunity and tissue remodelling. The molecular basis of this process - phagocytosis - is complex, involving - numerous receptors and signalling pathways. Nevertheless, the biophysical process is always the same: the cell membrane deforms and reshapes to wrap around the particle, and upon closure and abscission of the resultant cup, the particle is - internalised. Although the key molecular players in individual phagocytic pathways have been identified, we still know very little about the basic biophysics common to all phagocytic pathways. I propose to fill this gap in our knowledge by creating a - “minimal phagocyte”: I aim to reconstitute a minimal, dynamic actin cytoskeleton and artificial phagocytic receptors in giant unilamellar vesicles (GUVs), thereby identifying the molecular components that are not only necessary but also sufficient - for phagocytosis. Using synthetic biology to build a bottom-up model of phagocytosis should answer many open questions, including: are spatial cues resulting from particle binding required for membrane wrapping around the particle? Is directed - initiation of actin polymerisation sufficient to render GUVs capable of phagocytosis? What is the role of the membrane-supporting actin cortex and how does the affinity of the receptors affect the engulfment process? Beyond phagocytosis, the - minimal-model approach I propose will also be useful to study other cellular functions requiring actin-driven membrane reorganisation, such as cell mobility. In line with the objectives set by ERA-NET ERASynBio and the Horizon 2020 work programme - (which identified synthetic biology as one of the “cutting-edge biotechnologies as future innovation drivers”), the creation of “protocells” will not only enhance our understanding of biology, but ultimately also result in novel biotechnological - applications, such as improved drug delivery systems. - - 2018-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - minimal-phagocyte - - - H2020-MSCA-IF-2015 - - - 703132 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 946 250 - - - Logical Foundations for the Future of Safe Systems Programming - - - EUR 1 946 250 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - A longstanding question in the design of programming languages is how to balance safety and control. C-like languages give programmers low-level control over resource management at the expense of safety, whereas Java-like - languages give programmers safe high-level abstractions at the expense of control. - - 2021-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - RustBelt - - - ERC-2015-CoG - - - 683289 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 159 460,80 - - - A Computational Framework For Quantitative Modeling of Leaf Development in Arabidopsis and Cardamine - - - EUR 159 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Understanding how form emerges in living organisms is a fundamental challenge for biology. Progress, however, has been confounded by the complex chain of interactions underlying the organization of macroscopic forms from - molecular processes. Consequently, insights into the manner in which individual genes contribute to the development of form have been elusive; even in well-studied model organisms. In this context, leaves provide a striking example of the - self-organization of form – displaying remarkable diversity within and between species. Now, exploiting the close relation between simple leafed A. thaliana and compound leafed C. hirsuta, the Tsiantis lab has identified the key genetic factors - underlying their distinct leaf shapes. This opens the door to a detailed understanding of the developmental factors sculpting leaf form. - - - 2018-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - CFQMLD - - - H2020-MSCA-IF-2015 - - - 703886 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 159 460,80 - - - Density-Functional Theory for Thermoelectric Phenomena - - - EUR 159 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - The development of sustainable energy sources poses a great challenge for our society. Due to the scarcity of natural resources it is of crucial importance to optimize the efficiency of our energy production. Virtually every - energy generation process is accompanied with the generation of waste heat, for example in the form of plumes from power plants. Even if only part of this waste heat is transformed into useful energy the overall efficiency of energy production is - increased. In recent years there has been renewed interest in thermoelectric phenomena, due to their potential impact on designing new devices capable of converting waste heat into electricity. Furthermore, it has become evident that nanoscale - devices, which implement their functionality at the level of single molecules, potentially offer a much enhanced efficiency for the conversion of heat to electricity compared to bulk materials. - - 2018-10-14, ongoing project - - - 2016-10-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Germany - - - ThermalDFT - - - H2020-MSCA-IF-2015 - - - 701796 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 171 460,80 - - - Spectral synthesis of multidimensional supernova explosion models - - - EUR 171 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Core-collapse supernovae are the explosive deaths of massive stars. They are the main production sites of the heavy elements in the Universe, drive galactic dynamic and chemical evolution, and produce exotic remnants such as - black holes and neutron stars. To interpret observations and advance our understanding of the origin of the elements, sophisticated spectral models are needed. The main science objective in this proposal is to compute the first spectral models of - multi-dimensional core collapse explosion simulations. These models will then be compared with available high-quality data to derive information on nucleosynthesis yields and supernova structure. The proposed work involves the development of spectral - modelling tools from current 1D to multi-D capability, and application of these to recently computed state-of-the-art 3D explosion simulations. This innovative project will allow a milestone in supernova research to be reached by producing the first - light curves and spectra of modern 3D simulations, and will approach us to solving an almost 50 year standing mystery of how supernovae explode and how the elements are produced. - - 2018-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - SNSM - - - H2020-MSCA-IF-2015 - - - 702538 - - - - - UNIVERSITAT ZURICH - - - EUR 175 419,60 - - - Understanding and Boosting Motivation using Brain Stimulation - - - EUR 175 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - Imagine losing the motivation to do the job that you used to enjoy. The idea of doing those tasks overwhelms you. You cannot push yourself to give the best efforts and end up doing the bare minimum. What are the brain - processes that cause such depleted motivation and how can we restore the motivation to put in effort in order to achieve goals? To address these questions, I propose a series of studies to gain a theoretical and practical understanding of the causal - relationship between brain computations of effort and the motivation to energise behavior to achieve goals. Specifically I plan to conduct, for the first time, a combined brain stimulation-functional neuroimaging (Transcranial Magnetic - Stimulation-TMS; functional Magnetic Resonance Imaging-fMRI) experiment to perturb brain regions whose activity represents the amount of effort costs, and measure its impact on neural value computations in a remote but interconnected brain region - known to drive choice behavior. This change in causal interplay in the brain should have a quantifiable impact on the motivation to expend effort. I will then use this theoretical knowledge to design a large-scale application of an inexpensive brain - stimulation method (Transcranial Direct Current Stimulation-tDCS) to increase motivation, thus establishing a realistic and versatile protocol for restoring motivation in rehabilitative settings. In sum, my research will address the overarching - question of how motivation can be enhanced with neuroscience techniques, by combining computational and neuroimaging advances in effort discounting with causal brain stimulation methods. This project will allow me to be trained in the two most common - brain stimulation techniques at a pioneering lab in Europe, and forge a new collaborative research line at the Laboratory for Social and Neural Systems Research at the University of Zurich. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - BOOMSTIM - - - H2020-MSCA-IF-2015 - - - 702799 - - - - - UNIVERSITAT ZURICH - UNIVERSITAT ZURICH - - - EUR 2 000 000 - - - Mechanisms and functional significance of diffusion barriers for asymmetric segregation of age in neural stem cells - - - EUR 2 000 000 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Neural stem/progenitor cells (NSPCs) continue to generate new neurons throughout life in distinct regions of the mammalian brain. Adult neurogenesis has been implicated in brain function and altered neurogenesis has been - associated with a number of neuropsychiatric diseases such as depression and cognitive ageing. A key feature of somatic stem cell division is the ability to divide asymmetrically and symmetrically for neurogenic and self-renewing cell division, - respectively. However, it remains unknown how age is segregated in the context of somatic stem cell division, i.e., if the cellular history and the replicative age of the mother stem cell is passed onto its progeny. Thus, we hypothesized that – - similar to the previously described barrier that exists in budding yeast – somatic stem cells, and more specifically NSPCs, form a diffusion barrier during cell division to retain aging or senescence factors within the stem cell, generating a - mechanism for how age is asymmetrically distributed. Indeed, we found the existence of a diffusion barrier that is established during NSPC division, identifying a new mechanism of cellular segregation and asymmetry. With the program proposed here I - aim i) to study the effects of the barrier on asymmetric segregation of aging factors and to develop novel tools to visualize the mammalian diffusion barrier, ii) to characterize the presence of a diffusion barrier in endogenous NSPCs in relation to - cell division history, iii) to analyse the mechanisms underlying age-associated weakening of the NSPC diffusion barrier, and iv) to evaluate if genetic and pharmacological rescue of the barrier is sufficient to ameliorate the age-dependent decline of - neurogenesis. The insights gained from the studies proposed here have the potential to substantially advance our understanding of NSPC biology, to identify a new mechanism underlying the neurogenic process, and to reshape our understanding of - asymmetric cell division of somatic stem cells. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Switzerland - - - STEMBAR - - - ERC-2015-CoG - - - 682256 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 884 875 - - - The Physics of Galaxies 7 Gyr Ago - - - EUR 1 884 875 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Over the past decade, redshift surveys and multi-wavelength imaging campaigns have drawn up an empirical picture of how many stars had formed in which types of galaxies over the history of the universe. However, we have yet to - unravel the individual pathways along which galaxies evolve, and the physical processes that drive them. Continuing with the previous approach -- larger and deeper photometric samples -- is not adequate to achieve this goal. A change of focus is - required. - - 2021-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - LEGA-C - - - ERC-2015-CoG - - - 683184 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 984 375 - - - Ultrafast spin transport and magnetic order controlled by terahertz electromagnetic pulses - - - EUR 1 984 375 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - In order to fully exploit the electron spin as a signal carrier in future information processing, spins need to be transported and flipped as fast as possible. Spintronics research aims at implementing these operations by - electric fields in circuitry, but has so far been limited to frequencies below ~10 GHz. The much faster complementary femtomagnetism approach employs femtosecond laser pulses (carrier frequency ~400 THz), but is not compatible with microelectronics - technology. - - 2021-06-30, ongoing project - - - 2016-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - TERAMAG - - - ERC-2015-CoG - - - 681917 - - - - - UNIVERSITAT ZURICH - UNIVERSITAT ZURICH - - - EUR 1 489 340,95 - - - The Role of Local Protein Degradation in Neurotransmitter Release and Homeostatic Plasticity - - - EUR 1 489 340,95 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - While many neurons live for decades, the proteins that determine neural function have half-lives of hours to weeks. On the one hand, this allows for plastic changes during development and learning. On the other hand, this - poses the question of how stable neural function can be achieved and maintained at all. Several neurological diseases, such as epilepsy or migraine, have been linked to uncontrolled neural function. However, the molecular mechanisms that stabilize - nervous system function are poorly understood. The major site of regulation of neural activity is the chemical synapse. Synaptic function is tightly linked to the specific composition and abundance of proteins at synapses. However, the molecular - pathways underlying the homeostatic control of protein levels at synapses, henceforth called synaptic proteostasis, are largely unknown. - - 2021-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Switzerland - - - SynDegrade - - - ERC-2015-STG - - - 679881 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 171 460,80 - - - Towards a Complete Quantitative Model of the FOF1 ATP Synthase - - - EUR 171 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - The FOF1-ATPase is a complex nanomotor that synthesizes nearly 90% of the ATP made during cellular respiration. It consists of two coupled rotary motors: an integral membrane complex driven by proton flow across lipid bilayers - (FO) and an enzymatic complex that converts ADP and inorganic phosphate to ATP (F1). The rotational portion of these motors acts as a camshaft, inducing conformational changes that lead to ATP synthesis in the F1 motor’s three functional catalytic - sites. The F1 motor can perform ATP synthesis in the absence of FO, and it can also work in reverse, hydrolyzing ATP to pump protons against an established gradient. Over the last 30 years many important aspects of this motor’s function have been - elucidated by careful biochemical work and further understood by clever biophysical experiments. However, there is still not a complete, quantitative description of the whole thermodynamic cycle—one that fully describes the interactions between all - three separate catalytic sites and accounts for the need to exchange ATP (found abundantly) for the relatively sparse ADP. - - 2018-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - F-ATPase - - - H2020-MSCA-IF-2015 - - - 707154 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 497 374,99 - - - Rydberg dressed quantum many-body systems - - - EUR 1 497 374,99 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - The project “Rydberg dressed quantum many-body systems” (RyD-QMB) will experimentally study long-range interacting atomic quantum many-body systems with tailored microscopic interactions. It will explore supersolidity expected - for ultracold bosonic systems with soft-core interactions and realize quantum magnets, that are designable almost at will and feature unprecedented coupling strengths. As such, it opens new directions for atomic quantum simulation and paves the way - towards the experimental study and the design of frustrated magnets, interacting topological systems and artificial quantum gauge fields, topics, that not only push the limits of quantum simulators for solid state physics, but also reach out into the - field of high energy physics. - - 2021-05-31, ongoing project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - RyD-QMB - - - ERC-2015-STG - - - 678580 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 2 500 000 - - - Myelinic nanochannels in neurodegenerative diseases - - - EUR 2 500 000 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Myelin is made by highly specialized glial cells and enables fast axonal impulse propagation. We have discovered that oligodendrocytes in the CNS are, in addition to myelination, required for the integrity and survival of - axons, independent of the presence or absence of myelin itself. More recently, we found the underlying mechanism and could show that glycolytic oligodendrocytes provide axons with pyruvate/lactate. These metabolites are transported through a system - of myelinic nanochannels to the axonal compartment, in which mitochondria generate ATP. The finding was a paradigm-shift for the physiological function of axonassociated glia, and opens now the intriguing possibility that oligodendrocytes are - important modifiers of neurological diseases in which myelinated axons are lost. This includes, in addition to multiple sclerosis, also classical neuropsychiatric disorders. We will generate novel genetic tools in mice that allow us to study the role - myelin and secondary axonal loss in higher brain functions. We will test the challenging hypothesis that reducing oligodendroglial support of axonal metabolism is a risk for differen neurodegenerative disorders. These involve the previously neglected - ultrastructure of CNS myelin with cytosolic (20-300 nanometer wide) channels within the myelin sheath. These 'nanochannels' couple the oligodendrocyte soma metabolically to the adaxonal space, but are vulnerable to aging and physical injury. We - hypothesize that cellular mechanisms as diverse as neuroinflammation and the aggregation of misfolded proteins in myelinic nanochannels cause perturbations of the axonal energy metabolism. When combined, the findings of MyeliNANO will shed new light - on previously unknown functions of CNS myelin and will pave the way for metabolic neuroprotection as a therapeutic approach to a range of neurodegenerative diseases. - - 2021-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - MyeliNANO - - - ERC-2014-ADG - - - 671048 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 495 000 - - - Are social skills determined by early live experiences? - - - EUR 1 495 000 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Social bonding success in life impacts on health, survival and fitness. It is proposed that early and later social experience as well as heritable factors determine social bonding abilities in adulthood, although the relative - influence of each is unclear. In humans, the resulting uncertainty likely impedes psychological and psychiatric assessment and therapy. One problem hampering progress for human studies is that social bonding success is hard to objectively quantify, - particularly in adults. I propose to directly address this problem by determining the key influences on social bonding abilities in chimpanzees, our closest living relative, where social bonding success can be objectively quantified, and is defined - as number of affiliative relationships maintained over time with high rates of affiliation. - - 2021-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - ApeAttachment - - - ERC-2015-STG - - - 679787 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 500 000 - - - Elucidation of autophagy using novel chemical probes - - - EUR 1 500 000 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - The interest on autophagy, an evolutionarily conserved process in eukaryotes, has enormously increased in the last years, since autophagy is involved in many diseases such as cancer and neurodegenerative disorders. - Autophagosome formation is the key process in autophagy. Despite extensive work, the model of autophagosome formation is not yet well established. Some important questions on autophagosome biogenesis remain to be elusive, such as where the bona fide - marker protein of autophagosome, LC3, is lipidated, how lipidated LC3 functions in autophagosome formation, and how the proteins for LC3 lipidation and delipidation are involved in autophagosome formation. Although genetic approaches have been useful - to identify genes involved in autophagy, they are chronic and thereby the dynamics of phenotypic change cannot be followed, making them not suited for study highly dynamic process such as autophagosome formation. Herein, I propose to develop and use - novel chemical probes to address these issues. First, I plan to prepare semi-synthetic caged LC3 proteins and apply them to monitor dynamics of autophagosome formation in the cell in order to address those questions on autophagosome formation. The - semi-synthetic LC3 proteins are expected to confer a temporal control and to realize manipulation of protein structure, which renders such studies possible. Second, I intend to develop a versatile approach targeting specific endogenous proteins using - a reversible chemically induced dimerization (CID) system, termed as “knock on and off” strategy. I plan to use this approach to elucidate the function of two distinct PI3K complexes in autophagosome formation. On one hand, the establishment of novel - approaches will open up a new avenue for studying biological processes. On the other hand, the use of the tool will reveal the mechanism of autophagy. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - ChemBioAP - - - ERC-2015-STG - - - 678899 - - - - - UNIVERSITAT ZURICH - UNIVERSITAT ZURICH - - - EUR 1 991 721 - - - General Relativistic Effect in Galaxy Clustering as a Novel Probe of Inflationary Cosmology - - - EUR 1 991 721 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Substantial advances in cosmology over the past decades have firmly established the standard model of cosmology. However, the physical nature of the early Universe and dark energy (or inflationary cosmology) remains poorly - understood. To resolve these issues, a large number of galaxy surveys are planned to measure millions of galaxies in the sky, promising precision measurements of galaxy clustering with enormous statistical power. Despite these advances in - observation, the standard theoretical description of galaxy clustering is based on the Newtonian description, inadequate for measuring the relativistic effects from the early Universe and the deviations of modified gravity from general relativity. In - recent years, the applicant, for the first time, developed the linear-order general relativistic description of galaxy clustering and showed that the relativistic effect in galaxy clustering is already measurable at a few-sigma level in current - surveys like the Sloan survey - - 2021-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Switzerland - - - GREinGC - - - ERC-2015-CoG - - - 680886 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 999 625 - - - The tiny and the fast: the role of subcortical sensory structures in human communication - - - EUR 1 999 625 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - In Europe, approximately one hundred million people are impaired in their communication abilities. These include people with autism spectrum disorders (ca. 3 million) and individuals with dyslexia (ca. 50 million). Current - neuroscience research typically associates cognitive functions including communication abilities with the cerebral cortex. By and large, this approach ignores the complex subcortical processing machinery before sensory signals reach the cortex. - However, recent pioneering studies imply that dysfunction in tiny subcortical sensory structures can cause selective deficits in our ability to understand others. My goal is to (i) investigate the role of subcortical sensory structures in analysing - communication signals and (ii) specify how dysfunction in subcortical-cortical interaction can cause human communication disorders. To do this we will combine very recently developed ultra-high-resolution neuroimaging with a cutting-edge multimodal - approach including neurostimulation, and computational neuroimaging. The project will relate sensory subcortical responses to concrete communication behaviour, as observed in healthy individuals and individuals with communication disorders. I expect - two key results: First, we will uncover the principles of how subcortical sensory structures operate for dynamic auditory and visual communication signals; this will lead to a novel model of subcortical-cortical interactions that can explain key - functions in human communication. Second, the results will resolve long-standing puzzles about the nature of two of the most common hereditary communication deficits (developmental dyslexia and autism spectrum disorders). Immediate consequences of - this proposal will include a translational project aimed at improving communication functions with behavioural interventions. Together, the findings may revolutionise our understanding of how sensory subcortical structures shape one of our most - important cognitive functions—communication. - - 2020-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - SENSOCOM - - - ERC-2014-CoG - - - 647051 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 500 000 - - - Mechanisms of protein translocation in ER-associated protein degradation and the related protein import into the apicoplast of Plasmodium falciparum - - - EUR 1 500 000 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - The removal of misfolded proteins is an essential process in all cells. Failure to dispose of such proteins often results in disease. A particularly intriguing process serves to discard misfolded proteins from the endoplasmic - reticulum (ER). The ER does not itself degrade proteins, so machinery has evolved that moves misfolded proteins into the cytosol where they can be degraded by the proteasome. This retro-translocation process is called ERAD (for ER-associated protein - degradation). By comparison with other membrane translocation processes, the mechanism of ERAD is poorly understood. How are misfolded proteins distinguished from folding intermediates? How are proteins moved across the membrane? How is the energy - for membrane translocation provided? To answer these fundamental questions I will use a combination of in vitro reconstitution experiments with purified proteins from S. cerevisiae and experiments in intact yeast cells. It appears that some ERAD - components have been adapted to function in protein translocation in a very different setting. Many parasites like the malaria causing P. falciparum contain a plastid-like organelle, called the apicoplast. It is the site of several metabolic pathways - essential for the parasite’s survival, and thus an important drug target. Like other organelles of endosymbiotic origin, the apicoplast lost most of its genetic information and has to import proteins. This is a particularly challenging endeavour - because four membranes surround the apicoplast. It is thought that symbiont specific ERAD-like machinery (SELMA) mediates proteins translocation across the second-outermost membrane. However, not much is known about SELMA. What is its molecular - composition? Which aspects of SELMA are conserved in comparison to the classical ERAD machinery? I will address these important questions using a completely novel combination of biochemical and genetic approaches. - - 2021-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - ERAD_SELMA - - - ERC-2015-STG - - - 677770 - - - - - UNIVERSITAT ZURICH - UNIVERSITAT ZURICH - - - EUR 2 500 000 - - - Function and malfunction of the prion protein - - - EUR 2 500 000 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Transmissible spongiform encephalopathies (TSE) are caused by the ordered aggregation of PrPC into prions consisting of PrPSc. Similar pathogenetic principles operate in Alzheimer’s and Parkin-son’s disease, and a growing list - of further diseases whose prevalence is steadily rising. Familial TSE are invariably associated with PrPC mutations, and the dearth of genetic modifiers has hampered our understanding of prion diseases. Therefore, the first objective of my proposal - utilizes a cell-based high-throughput quantitative prion replication assay (developed during my previous ERC instalment) for genome-wide unbiased screens employing new genetics tools (CRISPR, siRNA li-braries, next-gen sequencing) to identify - modifiers of prion uptake, replication, and secretion. The second objective aims at clarifying the basis of prion neurotoxicity and will be developed along two alleys: (a) we will uncover the molecular basis of spongiosis (the neuronal vacuolation - characteristic of prion diseases), which we suspect to be a main driver of pathology, and (b) we will perform CRISPR-based synthetic lethality screens to identify genes that become essential to prion-infected cell lines (which do not experience prion - toxicity) and may not be expressed by neurons. The third objective is to understand the function of PrPC in cellular physiology, and focuses on our evidence that (a) PrPC interacts with an orphan G-protein coupled receptor to maintain peripheral - myelin integrity and (b) that PrPC may trigger cell death in response to ER stressors. While certain pathways of degeneration will undoubtedly be specific to prion infections, I expect that some targets will prove common to a variety of protein - aggregation diseases including Alzheimer’s and Parkinson’s disease, and may perhaps translate into novel diagnostics and therapeutics. Hence the proposed project may not only open new perspectives in prion biology but also yield insights applicable - to much more common diseases. - - 2020-10-31, ongoing project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Switzerland - - - PRION2020 - - - ERC-2014-ADG - - - 670958 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 2 750 000 - - - Spin Orbitronics for Electronic Technologies - - - EUR 2 750 000 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Spintronics is a vibrant field of research that involves the intimate interaction of magnetic structure on the atomic scale with spin currents and spin-polarized charge currents. SORBET is focussed on an emerging sub-field of - spintronics, namely that of spin orbitronics. Recent discoveries in this field concern the interplay of several distinct spin orbit coupling derived phenomena that, together, allow for the highly efficient current - - 2020-10-31, ongoing project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - SORBET - - - ERC-2014-ADG - - - 670166 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 171 460,80 - - - REalistic Simulations and ObservationaL Validation of small-scale Energy channels on the Sun - - - EUR 171 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Sun-like stars possess magnetically confined, upper atmospheres. These coronae have temperatures of several million degrees and thus are much hotter than the underlying stellar surfaces (photospheres) which have temperatures - of the order of 6000 degrees. The coronae are hotter than the photospheres because magnetic energy is generated by convective motions beneath the stellar surface and then transported through the photosphere into the corona where it is dissipated. The - key to understanding the heating of the corona is to determine how, and at which spatial and temporal scales, energy is being transported into the stellar atmosphere. Both theory and simulations suggest that a substantial fraction of the energy - transfer happens at spatial scales smaller than those currently observationally resolvable. The main goal of the proposed research is to bridge this gap between what we expect from theory and what we can observe. The proposed research will use - numerical simulations to characterize the energy flux and look for its (spectropolarimetric) signature. This signature will then be used to create maps of the energy flux on the actual Sun using the highest-resolution observations (50-70 km) which - are available: those from the 1-meter Sunrise balloon-borne observatory, and the 1.5-meter GREGOR, Europe's largest solar telescope. We will validate the diagnostics by comparing these maps of the observed energy flux into the solar atmosphere with - co-spatial observations of the hot plasma structures seen in the upper atmosphere. Understanding the energy transfer combines the strengths of advanced simulations and the unprecedented observations as well as combining the expertise of world-leading - solar groups in Germany and Spain. This research will have a major impact on our understanding of the heating of upper atmosphere. It is the ideal project and set of collaborations to further the experienced researcher's scientific career. - - 2018-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - RESOLVE - - - H2020-MSCA-IF-2015 - - - 707837 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 2 495 593,75 - - - Presynaptic Regulatory Principles in Synaptic Plasticity, Neuronal Network Function, and Behaviour - - - EUR 2 495 593,75 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Neuronal signalling via synaptic vesicle (SV) fusion is the fastest membrane fusion event in mammalian cells. Its speed and the ability of presynapses to sustain SV fusion at high stimulation rates are key requirements for - brain function. Plastic changes of SV fusion rates have long been thought to control complex brain processes such as working memory, but the link between presynaptic plasticity and complex brain functions remains hypothetical. A key determinant of - presynaptic efficacy is that synapses maintain a release-ready or primed SV pool that can be refilled rapidly. SV priming is mediated by a set of dedicated priming proteins (Munc13s, CAPSs, and accessory proteins), which are of pervasive and - essential functional importance for synaptic efficacy, and - based on in vitro studies - of capacious potential to regulate exactly the type of synaptic plasticity that is associated with brain circuit characteristics involved in complex behaviours. - However, this 'catholic' role of the SV priming machinery in brain function has never been tested, mainly because essential genetic models for studies in vivo have been lacking. Using (i) 4 newly generated conditional KO and KI mouse lines, (ii) 17 - additional KOs/KIs (12 ours), (iii) high-end EM approaches (iv) KO-replacement strategies, (v) electrophysiological and optophysiological analyses, and (vi) behavioural studies, we will examine the SV priming machinery in intact circuits in order to - (a) define the mechanisms and cell biological basis of SV priming, of its dynamics, and of defined priming-dependent synaptic plasticity states, and to (b) define the causal links between SV priming, synapse function, synaptic plasticity, circuit - characteristics, and behaviour. These studies will generate a comprehensive delineation of the role of SV priming in intact neural circuits, which is not only essential for basic science but also for psychiatry, because all key priming proteins are - linked to neuropsychiatric diseases. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - SYNPRIME - - - ERC-2014-ADG - - - 670283 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 2 000 000 - - - Comparative analysis of planarian regeneration - why some worms regenerate while others don’t - - - EUR 2 000 000 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - The ability to regenerate lost body parts is widespread amongst animals, yet humans, for example, can only regenerate specific organs. Why some animals regenerate while others hardly do remains a fascinating conundrum, - especially so in face of “survival of the fittest”. Even amongst planarian flatworms, famous for their ability to regenerate from random tissue fragments, species exist that have completely lost the ability to regenerate. This proposal will exploit - the unique diversity of planarian regenerative abilities amongst to ask why some worms regenerate while others do not. We and others have established that planarian Wnt signalling acts as critical node in the evolution of regeneration defects. Using - this finding as strategic focus for comparisons between regenerating and non-regenerating species, we will investigate i) the cell biological mechanisms that shape Wnt pathway activity; ii) the genomic mechanisms that differentially deploy critical - pathway regulators; and iii) evolutionary mechanisms in form of life history trait trade-offs as possible driving force behind the drift of regenerative abilities. Key to the project is a diverse collection of regenerating and regeneration-deficient - species that my lab has established. Focused comparisons between our two primary model species D. lacteum and S. mediterranea, employing pan-planarian antibodies and functional genomics, will allow us to understand the detailed causes of altered - pathway activity. Comparisons amongst the entire collection of 50 species will provide the necessary breadth for identifying and studying the evolutionary principles that “naturally select” regeneration-deficient planarians. The comparative approach - of RegEvolve will thus uniquely bridge the proximate (molecular)- with the ultimate (evolutionary) causes of regeneration defects and such interdisciplinary endeavour between molecular and evolutionary regeneration research will lead to new and - profound insights into both fields. - - 2020-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - RegEvolve - - - ERC-2014-CoG - - - 649024 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 2 000 000 - - - Millet and beans, language and genes. The origin and dispersal of the Transeurasian family. - - - EUR 2 000 000 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - The question about the origin and dispersal of the Transeurasian languages (i.e. Japonic, Koreanic, Tungusic, Mongolic and Turkic) is one of the most disputed issues in linguistic history. Eurasia3angle will address this - question from an interdisciplinary perspective. My key objective is to effectively synthesize linguistic, archaeological and genetic evidence in a single approach, for which I use the term "triangulation". To this end, my project will bring together - a highly qualified interdisciplinary team of doctoral and postdoctoral researchers along with world-eminent experts, who will focus on testing the Farming/Language Dispersal Hypothesis for the Transeurasian languages. The FLDH attributes the - dispersal of some of the world's major language families to the adoption of agriculture and subsequent population expansion, whereby the language of new farmers displaced that of preexisting hunter gatherers. In contrast to its application to the - major language families in East Asia, the FLDH has not been tested yet for the Transeurasian languages. My research team will specifically investigate the hypothesis that the Transeurasian languages derive from a homeland in South Manchuria and that - their early dispersal should be associated with the spread of cultivation of millet and beans. For this purpose, we will use advanced techniques recently introduced to the individual disciplines, such as the application of phylogenetic methods to - linguistic classification, a focus on derivational morphology in the reconstruction of subsistence-related language, a matrix-based comparison of archaeological cultures and a model-based approach applied to genome-wide autosomal data. Converging - these partial perspectives into a more holistic understanding of what really happened in the past is quite a challenge. However, if successful, this research will be a break-through in the investigation of human prehistory in general and in the - long-standing Transeurasian debate in particular. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - Eurasia3angle - - - ERC-2014-CoG - - - 646612 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 266 750 - - - Origins of the Molecular Cloud Structure - - - EUR 1 266 750 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Understanding the physical processes that control the life-cycle of the interstellar medium (ISM) is one of the key themes in the astrophysics of galaxies today. This importance originates from the role of the ISM as the - birthplace of new stars, and therefore, as an indivisible component of galaxy evolution. Exactly how the conversion of the ISM to stars takes place is intricately linked to how the internal structure of the cold, molecular clouds in the ISM forms and - evolves. Despite this pivotal role, our picture of the molecular cloud structure has a fundamental lacking: it is based largely on observations of low-mass molecular clouds. Yet, it is the massive, giant molecular clouds (GMCs) in which most stars - form and which impact the ISM of galaxies most. I present a program that will fill this gap and make profound progress in the field. We have developed a new observational technique that provides an unparalleled view of the structure of young GMCs. I - also have developed a powerful tool to study the most important structural characteristics of molecular clouds, e.g., the probability distribution of volume densities, which have not been accessible before. With this program, the full potential of - these tools will be put into use. We will produce a unique, high-fidelity column density data set for a statistically interesting volume in the Galaxy, including thousands of molecular clouds. The data set will be unmatched in its quality and extent, - providing an unprecedented basis for statistical studies. We will then connect this outstanding observational view with state-of-the-art numerical simulations. This approach allows us to address the key question in the field: Which processes drive - the structure formation in massive molecular clouds, and how do they do it? Most crucially, we will create a new, observationally constrained framework for the evolution of the molecular cloud structure over the entire mass range of molecular clouds - and star formation in the ISM. - - 2021-01-31, ongoing project - - - 2016-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - PROMISE - - - ERC-2014-STG - - - 639459 - - - - - UNIVERSITAT ZURICH - UNIVERSITAT ZURICH - - - EUR 2 498 915 - - - Mesoscale Brain Dynamics: Computing with Neuronal Pathways - - - EUR 2 498 915 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Brain computations rely on proper signal flow through the complex network of connected brain regions. Despite a wealth of anatomical and functional data – from microscopic to macroscopic scale – we still poorly understand the - principles of how signal flow is routed through neuronal networks to generate appropriate behavior. Brain dynamics on the 'mesoscopic' scale, the intermediate level where local microcircuits communicate via axonal pathways, has remained a particular - blind spot of research as it has been difficult to access under in vivo conditions. Here, I propose to tackle the mesoscopic level of brain dynamics both experimentally and theoretically, adopting a fresh perspective centered on neuronal pathway - dynamics. Experimentally, we will utilize and further advance state-of-the-art genetic and optical techniques to create a toolbox for measuring and manipulating signal flow in pathway networks across a broad range of temporal scales. In particular, - we will improve fiber-optic based methods for probing the activity of either individual or multiple neuronal pathways with high specificity. Using these tools we will set out to reveal mesoscopic brain dynamics across relevant cortical and - subcortical regions in awake, behaving mice. Specifically, we will investigate sensorimotor learning for a reward-based texture discrimination task and rapid sensorimotor control during skilled locomotion. Moreover, by combining fiber-optic methods - with two-photon microscopy and fMRI, respectively, we will start linking the meso-level to the micro- and macro-levels. Throughout the project, experiments will be complemented by computational approaches to analyse data, model pathway dynamics, and - conceptualize a formal theory of mesoscopic dynamics. This project may transform the field by bridging the hierarchical brain levels and opening significant new avenues to assess physiological as well as pathological signal flow in the brain. - - 2021-01-31, ongoing project - - - 2016-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Switzerland - - - BRAINCOMPATH - - - ERC-2014-ADG - - - 670757 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 500 000 - - - Metabolic and Genetic Regulation of Ageing - - - EUR 1 500 000 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Ageing is a complex physiological process that affects almost all species, including humans. Despite its importance for all of us, the biology of ageing is insufficiently understood. To uncover the molecular underpinnings of - ageing, I propose an interdisciplinary research program that will identify and investigate metabolic and genetic regulators of ageing. - - 2020-07-31, ongoing project - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - MetAGEn - - - ERC-2014-STG - - - 640254 - - - - - UNIVERSITAT ZURICH - UNIVERSITAT ZURICH - - - EUR 2 913 143,75 - - - Film Colors. An Interdisciplinary Approach. - - - EUR 2 913 143,75 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Film is in essence colored light projected onto a screen. Its aesthetics are thus highly determined by the material properties of film and the optical configuration of the cinematic apparatus. To this day, however, there is no - systematic study of the relationship between the technology and aesthetics of film colors, despite the fact that, following the digital turn in film production and distribution, the understanding of this relationship is more essential than ever - before. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Switzerland - - - Filmcolors - - - ERC-2014-ADG - - - 670446 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 2 484 375 - - - Crystalline and vitreous silica films and their interconversion - - - EUR 2 484 375 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Silicon is the most abundant element in the earth’s crust. Its oxide, silica (SiO2) is the basis for most minerals of the earth’s crust, and also for a number of technological applications ranging from window glass, via - electronics to catalysis. The structure of crystalline materials such as quartz or silica-based minerals is well understood due to the application of scattering techniques such as x-ray or neutron diffraction, for example, which allow accurate - structure determinations. Silica, however, also forms glasses, which are amorphous or vitreous. Its structure is not well understood. In fact, diffraction techniques have only been able to deliver pair correlation functions, which reveal the density - of a material around a given atom, but do not allow a detailed reconstruction of the atomic structure as in the case of crystalline materials. Until recently, a real space image of a silica glass with atomic resolution had not been recorded. Using - scanning probe techniques applied to a thin silica film grown atomically flat on a metal substrate, it has been possible to reveal, for the first time, an atomically resolved image of vitreous silica. Both, a crystalline as well as a vitreous phase - have been imaged. With this system, it is now possible to address the transition from a vitreous state to a crystal-line in real space by developing a scanning probe microscope that allows the study of its structure over a wide range of temperatures - ranging from cryogenic temperatures to 1500 K. It is the purpose of this grant application to build such a device and apply it to the crystal-glass transition and the study of vibrational properties. This instrument may also be used to address a - number of scientific problems related to other glass-formers, such as borates and the influence of silica modifications by atom doping, for example. - - 2020-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - CRYVISIL - - - ERC-2014-ADG - - - 669179 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 3 176 850 - - - Collective modes in 4d-metal compounds and heterostructures - - - EUR 3 176 850 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Compounds of transition metals with 4d valence electrons (“4d metals”) play eminent roles in many areas of condensed matter physics ranging from unconventional superconductivity to oxide electronics, but fundamental questions - about the interplay between the spin-orbit coupling and electronic correlations at the atomic scale remain unanswered. Momentum-resolved spectroscopies of collective electronic excitations yield detailed insight into the magnitude and spatial range - of the electronic correlations, and have thus decisively shaped the conceptual understanding of quantum many-body phenomena in 3d-electron systems. We will devise and build a novel resonant inelastic x-ray scattering (RIXS) instrument capable of - determining the dispersion relations of electronic collective modes in 4d-metal compounds with full momentum-space coverage, high energy resolution, and monolayer sensitivity. - - - 2020-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - Com4Com - - - ERC-2014-ADG - - - 669550 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 2 500 000 - - - Reshuffling genes and genomes: from experimental evolution to synthetic biology in plants - - - EUR 2 500 000 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - GENEVOSYN has three highly ambitious objectives that will enable the engineering of new generations of crop plants. The project consists of three complementary workpackages (WPs) and will use both synthetic genomes and - naturally available genomes as raw material for novel biotechnology and synthetic biology approaches. It will employ experimental gene and genome transfer as well as recently discovered natural (horizontal) genome transfer processes to generate new - crop varieties and species. In WP1, the plastid (chloroplast) will be developed as a highly efficient platform for synthetic biology applications in plants. This will be accomplished by pursuing bottom-up and top-down synthetic biology approaches. - They include the construction of large synthetic multigene operons towards introducing new complex metabolic pathways into plants, and the design, synthesis, assembly and booting up of radically redesigned synthetic genomes that ultimately will allow - us to expand the genetic code and thereby the amino acid repertoire of plant cells. In WP2, GENEVOSYN aims at developing a technology for mitochondrial genome engineering in plants. The possibility to alter the genetic information in plant - mitochondria by transformation would revolutionize both basic and applied research on plant mitochondria, and pave the way to harnessing the enormous potential of mitochondrial biotechnology. Finally, WP3 will exploit recently discovered horizontal - genome transfer processes for the creation of novel crop species and the improvement of existing ones. To this end, we will use grafting-assisted horizontal genome transfer between crop species in the nightshade family (Solanaceae) to (i) generate - new combinations of nuclear and plastid genomes and determine the impact of the plastid genome and specific plastid genes on plant growth and stress tolerance, and (ii) produce novel (synthetic) species that arise from the combination of entire - nuclear genomes of existing species. - - 2020-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - GENEVOSYN - - - ERC-2014-ADG - - - 669982 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 2 500 000 - - - Novel Cells for Organ Repair - - - EUR 2 500 000 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - In adult organisms, the natural ability to regenerate tissues damaged by injury or aging resides in multipotent tissue-specific precursors in local microenvironments. The number of these precursors is often either limited or - declines sharply with age. Moreover, long-term adverse side effects of cancer treatments affect patients of any age. Such treatments tend to diminish the stem cell and progenitor cell populations. - - 2020-07-31, ongoing project - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - PROMETHEUS - - - ERC-2014-ADG - - - 669168 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 78 125 - - - CoPIRL: Compact High Power Picosecond Infrared Laser for Scar Free Surgery and Bio-Diagnostics. - - - EUR 78 125 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - The PIRL concept is the first method of any to achieve surgery without scar tissue formation. This new laser concept has achieved the long held promise for the laser for attaining the fundamental limit to minimally invasive - surgery. The very prospect of high precision surgery without scar tissue formation is readily appreciated to potentially revolutionize surgery and holds equally great promise in providing in situ bio-diagnostics. - - 2016-12-31, closed project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2014 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Germany - - - CoPIRL - - - ERC-2014-PoC - - - 640678 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 2 064 583 - - - Molecular reconstitution of epigenetic centromere inheritance - - - EUR 2 064 583 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Accurate segregation of the parental genome to the daughter cells during mitosis is essential for cell and organismal viability, protecting against cell death or cellular transformation. Kinetochores are crucial for accurate - chromosome segregation because they link chromosomes to spindle microtubules. Kinetochores sprout from unique chromosomal loci named centromeres. In most eukaryotes, centromere specification does not rely on defined DNA sequences. Rather, centromere - specification relies on epigenetic mechanisms, the most prominent of which is identified in the enrichment at centromeres of the histone H3 variant CENP-A. Deposition of new CENP-A at every cell cycle is vital for centromere maintenance through cell - division. RECEPIANCE aims to dissect the molecular mechanism of CENP-A deposition through reductionist approach based on two main pillars, biochemical reconstitution and structural analysis. - - - 2020-07-31, ongoing project - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - RECEPIANCE - - - ERC-2014-ADG - - - 669686 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 499 946 - - - Gut Microbiota in Nervous System Autoimmunity: Molecular Mechanisms of Disease Initiation and Regulation - - - EUR 1 499 946 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Multiple Sclerosis (MS), an autoimmune demyelinating disease affecting the central nervous system (CNS), causes tremendous disability in young adults and inflicts huge economic burden on the society. The incidence of MS is - steadily increasing in many countries arguing for environmental factors driven changes in disease induction. How and which environmental factors contribute to disease initiation and progression is unknown. Using a spontaneous mouse model of MS, we - have shown that the gut microbiota is essential in triggering CNS autoimmunity. In contrast to the mice housed in conventional housing conditions, germ free (GF) mice, devoid of gut bacteria, were protected from spontaneous experimental autoimmune - encephalomyelitis (sEAE). Re-colonization of GF mice with a complex regular gut flora derived from specific pathogen free (SPF) mice resulted in sEAE within 2-3 months. The re-colonization also triggered pro-inflammatory T and B cell responses. - However, colonization of GF mice with a reduced gut flora failed to induce sEAE during our observation period suggesting a “specific” rather than a “broader” microbial trigger. In this proposal, I want to study the role of gut microbiota in CNS - autoimmunity with the following aims: - - 2020-05-31, ongoing project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - GAMES - - - ERC-2014-STG - - - 635617 - - - - - LUNDS UNIVERSITET - LUNDS UNIVERSITET - - - EUR 2 442 000 - - - Towards a deepened understanding of combustion processes using advanced laser diagnostics - - - EUR 2 442 000 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The field of combustion is of utmost societal/industrial importance while at the same time posing outstanding scientific challenges. In order to handle these, it is extremely important to develop and apply non-intrusive - laser-diagnostic techniques with high spatial and temporal resolution for measurements of key parameters such as species concentrations and temperatures. Such techniques have been developed and applied by the PI for more than thirty-five years and - the home institute has one of the most advanced instrumentations in academia world-wide. - - - 2020-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Sweden - - - TUCLA - - - ERC-2014-ADG - - - 669466 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - STICHTING KATHOLIEKE UNIVERSITEIT - - - EUR 1 500 000 - - - Greenhouse Gas Mitigation through Advanced Nitrogen Removal Technology - - - EUR 1 500 000 - - - Germany - Germany - Netherlands - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Higher or Secondary Education Establishments - - Human activities have severe impacts on the biological carbon and nitrogen cycles. The most important consequences of these are global warming and water pollution. Wastewater treatment technology, in particular nitrogen - removal systems, improved considerably in the last decade. The application of anaerobic ammonium oxidizing (anammox) bacteria in oxygen-limited granules has the potential to turn wastewater treatment plants into energy-efficient systems with minimal - greenhouse gas emissions of carbon dioxide, nitrous oxide and methane. Recently, microorganisms that couple the anaerobic oxidation of methane to denitrification were discovered. An innovative integration of these microorganisms into partial - nitritation-anammox systems for wastewater treatment offers an elegant and efficient solution to combat greenhouse gas emissions from wastewater treatment plants. The aim of the GREENT project is to determine nitrous oxide emissions from partial - nitritation-anammox bioreactors and the parameters that govern these emissions, and to investigate the responsible pathways in molecular detail. Furthermore, I will explore the feasibility of an innovative bioreactor, which will remove ammonium and - methane simultaneously through anammox and anaerobic methane-oxidizing microorganisms. This approach will turn the otherwise harmful methane into a resource for efficient nitrogen removal. These fundamental insights and technological advances will be - achieved by a complimentary array of state-of-the-art methodology such as continuous culturing, stable isotope tracing and a combination of -omics methods together with physiological experiments and detailed measurements at full-scale installations. - The results of this proposal will be of paramount importance for the wastewater treatment sector, but also indispensable for mathematical modelling, life cycle assessment and understanding the ecophysiology of the involved microorganisms. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - GREENT - - - ERC-2014-STG - - - 640422 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 159 460,80 - - - Modeling the chronology of deep ocean circulation changes during abrupt climate transitions - - - EUR 159 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - The deep ocean circulation affects climate and the global carbon cycle. A prerequisite for improving confidence in future climate projections is the accurate reproduction of past deep ocean circulation changes by models. - However our understanding of such changes in terms of transport pathways and transit times is impeded by ambiguities in the chronology of ocean archives. This project aims at helping resolve such ambiguities by investigating to what extent the - temporal evolution of the ocean circulation during abrupt climate transitions may be inferred from deep-sea sediment cores. - - 2018-03-18, ongoing project - - - 2016-03-19 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - OCTANT - - - H2020-MSCA-IF-2014 - - - 660893 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 159 460,80 - - - Structural and mechanistic study of ion transport in Channelrhodopsin-2 - - - EUR 159 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Channelrhodopsins are type-I rhodopsin proteins found in green algae that function as sensory photoreceptors and turn into ion channels under illumination. Upon light absorbance, the retinal moiety induces a conformational - change on the protein that opens a channel through which ions can pass. - - 2017-03-31, closed project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - LIIT-ChR2 - - - H2020-MSCA-IF-2014 - - - 661784 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 147 094 - - - Rapid and Inexpensive Diagnosis of Heparin Induced Thrombocytopenia Using Glycan Arrays Containing Synthetic Glycosaminoglycans - - - EUR 147 094 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Rapid and Inexpensive Diagnosis of Heparin Induced Thrombocytopenia Using Glycan Arrays Containing Synthetic Glycosaminoglycans Heparin, a complex glycosaminoglycan (GAG) carbohydrate, is the most commonly used anticoagulant. - Twelve million patients in the EU are treated annually for conditions including acute coronary syndrome, deep-vein thrombosis and cardiopulmonary bypass surgery. Heparin-induced thrombocytopenia (HIT) is a dangerous adverse side effect of heparin - administration. HIT-II develops after major surgery or dialysis and results in infarction, multi-organ failure and 20% mortality. In Europe 100,000 patients develop HIT-II annually. - - 2016-09-30, closed project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2014 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Germany - - - HITCHIPDIAG - - - ERC-2014-PoC - - - 665607 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 159 460,80 - - - No Biofouling Surfaces - - - EUR 159 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Biofilms consist of bacteria, proteins and cells which attached to a solid surface. Prevention of biofilms is of extreme relevance in industry and science as they are ubiquitous and able to provoke corrosion or failure in - pipelines, heat exchangers, biomedical devices, artificial implants or food processing facilities. Biofilms are often battled with antibiotics, but bacterial resistance is a major problem. Therefore, novel approaches are required to avoid biofouling. - We will explore the application of (1) superamphiphobic coatings, (2) slippery liquid infused porous surfaces and (3) functional pillar arrays surfaces to battle biofouling. These surfaces have in common that they strongly repel water, blood and - organic liquids, and even soap-water mixtures due to a synergy between rough topography and a special chemistry. We will monitor and characterize the adhesion of bacteria, proteins and cells to these surfaces depended on shape, size and chemical of - composition of the surface and the liquids. Several classical and highly advanced cutting edge methods will be used to investigate the wetting and fouling properties of these surfaces, especially laser scanning confocal microscopy. In the final steps - of the research, we will evaluate the robustness of the surfaces and the biocompatibility in order to establish potential real applications in collaboration with industrial partners. We exert a high impact of this fellowship to the scientific - community and the rest of society. - - 2017-03-31, closed project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - NoBios - - - H2020-MSCA-IF-2014 - - - 660523 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 159 460,80 - - - Experimental Studies of Strongly Interacting Quantum Gases in an Optical Lattice - - - EUR 159 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Quantum gas systems have been recognized as quantum simulators that can directly compare theoretical models and experiments because of unprecedented experimental conditions. Here, we propose experimental studies on strongly - interacting quantum gases in an optical lattice. The key ingredients of our research are the strong and long-range dipolar interactions from Rydberg excited states and two-component Bosonic atoms in optical lattices, which can simulate Heisenberg - Hamiltonian. - - - 2017-04-30, closed project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - RyM - - - H2020-MSCA-IF-2014 - - - 660452 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 171 460,80 - - - Integrin specificity in rigidity sensitive proliferation, activation and directional migration of endothelial cells - - - EUR 171 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Cells have the extraordinary ability to regulate their morphology, functions and fate to minimal changes in the extracelullar microenvironment. Through multi-protein, cell-matrix adhesions they are able to recognize and - respond not only to the chemical diversity of the extracellular matrix (ECM), but also to its physical and topographical features. Mechanical and structural cues encoded in the ECM have an essential role in healthy tissue function where - contractility, spreading and proliferation are intricately regulated by cell-cell and cell-matrix adhesion and tension. Unsurprisingly, abnormal ECM mechanics are directly associated with disease and tissue malformation (atherosclerosis, wound - healing and tumor formation). Understanding the mechanisms cells use to sense and transduce mechanical signals, as well as the contribution of key players in the process is a pressing, unmet challenge. - - - 2017-08-31, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - ISPADMEC - - - H2020-MSCA-IF-2014 - - - 660205 - - - - - STIFTUNG FRANKFURT INSTITUTE FOR ADVANCED STUDIES - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 257 860,80 - - - Bayesian computations in the human neocortex: deciphering the neuronal mechanisms of perceptual and syntactic inferences. - - - EUR 257 860,80 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - The diversity of human cognitive abilities contrasts with the homogeneity of its neural bases. Indeed, perception, decision and language processes largely rely on a common neuronal structure – the neocortex – whose functioning - remains remarkably poorly understood. Recent theories suggest that the six layers of the neocortical microcircuit are specifically interconnected to perform generic computations, thanks to a Bayesian hierarchical combination of top-down expectations - (priors) and bottom-up sensory information (likelihoods). However, recording each cortical layer is technically challenging. Mainly limited to animal electrophysiology, the rare empirical investigations of neocortical operations have been incapable - of tackling human-specific cognitive abilities, such as syntax processing. Capitalizing on recent advances in human electrophysiology, I will address these challenges by testing whether the elements of Bayesian computations are implemented by 1) - distinct cortical layers (e.g. priors in layers 5/6) or, alternatively, 2) distinct neuronal oscillations (e.g. priors in the alpha/beta band). I will then assess whether these neuronal computations form the elementary components of syntax - processing. To characterize the exchange of information within and between cortical regions, I will combine whole-brain magnetoencephalography of with invasive electrocorticography and intra-laminar recordings, acquired from patients implanted for - clinical purposes. This project, at the intersection of neuroscience, computational theory and linguistics will set the foundations for a mechanistic investigation of human cognition at an unprecedented level of detail, and will therefore allow me to - start a competitive scientific career as an independent researcher. Ultimately, this innovative framework will help us understand the building blocks of human cognition, and the way neocortical dysfunctions lead to complex mental disorders such as - schizophrenia. - - 2018-07-31, ongoing project | - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Germany - - - BayesianHumanCortex - - - H2020-MSCA-IF-2014 - - - 660086 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 159 460,80 - - - An astrochemical study of the early evolutionary stages of sub-stellar mass objects - - - EUR 159 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Astrochemistry is an inter-disciplinary field that provides an insight into the complex physical and chemical processes at play during the early evolutionary stages in star-formation. Over the last decade, while astrochemical - studies have been conducted to understand the early evolutionary stages in high- and low-mass stars, similar work is essentially missing for the least massive stars, called brown dwarfs (BDs). BDs are ‘sub-stellar’ objects with insufficient mass to - burn hydrogen in their cores and shine like stars, but are found as abundantly as Sun-like stars in star-forming regions, making them an equally vital constituent of our Galaxy. ABDES is an innovative inter-disciplinary project, which will deliver - radically new advancements in our understanding of the astrochemical processes that occur during the early evolutionary stages in BD-formation. The objectives of ABDES are to characterize the physical and chemical structure of early-stage BDs, and - study the fundamental role played by the accretion and outflow processes in shaping their evolution. With the advent of high-class telescopes and instruments with unparalleled sensitivities, it is now feasible to probe deep into the early - evolutionary stages of BDs. To achieve these objectives, I have built the largest sample to date of early-stage BDs, using a new set of deep, high-sensitivity, multi-wavelength observations. ABDES will combine these observations with - chemical/physical modelling techniques, and provide the first measurements on the astrochemical properties of early-stage BDs. Being an inter-disciplinary research division, the Centre for Astrochemical Studies at MPE, under the supervision of Prof. - Caselli, is a great fit to this project, and provides excellent expertise and infrastructure for its successful implementation. ABDES is a pioneering study that will highlight the origins of the faintest stars in our Galaxy, and complete our - understanding of star-formation toward the lowest mass end. - - 2017-08-31, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - ABDES - - - H2020-MSCA-IF-2014 - - - 659383 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 171 460,80 - - - Nonlinear optical coatings at high intensities - - - EUR 171 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Optical interference coatings have become a key enabling technology for many laser systems. Modern oscillators and amplifiers are capable of generating ultrashort pulses with energies of several tens of µJ at repetition rates - of more than 10 MHz, resulting in several hundreds of watts of average output power. Under the illumination of optical coatings by such intense optical fields, the nonlinear effects manifest themselves. These effects can be exploited for development - of novel types of nonlinear optical (NLO) laser components: dielectric multilayer coatings with specified nonlinear properties. In order to use the potential of dielectric coatings as NLO devices, the nonlinear behaviour of dielectric multilayers at - intensities which are, from one side, high enough to activate nonlinearities and lower, from other side, than laser damage threshold, has to be carefully explored. As structures of films differ from the ones of bulk materials, then characterization - of nonlinear effects in dielectric coatings is to be carried out and numerical values of coatings’ nonlinear parameters are be estimated. - - 2017-09-30, closed project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - Germany - - - NICOS - - - H2020-MSCA-IF-2014 - - - 657596 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 159 460,80 - - - Mitochondrial Dynamics and Local Protein Synthesis in Dendrites - - - EUR 159 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Neurons are specialized cells with polarized morphology. Efficient function dictates that the molecular events crucial for synaptic communication are not centralized at the cell body but distributed to individual subcellular - compartments - dendrites, dendritic spines, axons, presynaptic terminals. Local protein synthesis in dendrites is one such mechanism that plays a significant role in synaptic plasticity and memory. However, little is known on how the high-energy - demands of local protein synthesis are met at dendrites and spines. Mitochondria, the 'energy houses' of cells, are found in great abundance in neurons. Mitochondria are associated with: nuclear-encoded messenger RNAs for local translation of great - majority of mitochondrial proteins; non-coding RNAs for translational regulation of its protein abundance. To meet the local energy demands of protein synthesis, it is likely that mitochondria compartmentalize at dendritic regions and undergo dynamic - changes in their proteome and transcriptome. My research project aims at elucidating the dynamics of mitochondria during high-energy demands of local protein synthesis. I will be performing experiments to examine mitochondrial compartmentalization in - dendrites. Since simple fluorescence time-lapse imaging is not sensitive enough to visualize mitochondrial dynamics, I will use state-of-the-art imaging tools available in Dr. Erin Schuman’s lab for my experiments. I will also exploit the special - neuron culture platforms, Microfluidic chambers, co-invented in the Schuman lab, for this purpose. In addition, I will be performing proteomic and transcriptomic analysis of mitochondria isolated from somata and neurites. To this end, I will use the - shared protein mass spectometry facility of the Max Planck Institute for Brain Research and Biophysics for mitochondrial proteomics and the advanced RNA sequencing techniques employed in the Schuman group for mitochondrial transcriptomics. - - 2017-12-31, closed project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - NEUROMITO - - - H2020-MSCA-IF-2014 - - - 657702 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 159 460,80 - - - Mechanisms of natural auto immunity triggered by plant NLR immune receptors - - - EUR 159 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Resistance (R) loci with nucleotide binding/leucine rich repeat (NB-LRR or NLR) domains have been identified as the major causal genes for hybrid necrosis, which presents an extreme example of the trade-off between plant - growth and the activation of immune system. This is an exciting finding both for plant breeders and plant pathologists. However, how these NLR proteins or even the whole NLR family lead to hybrid necrosis, how they contribute to fitness under natural - conditions, and how this is reflected in their extreme sequence variation remain largely unknown. In this proposal, I plan to exhaustively explore their function by systematically knocking out the NLR loci from genome of different Arabidopsis - accessions using genome editing, and testing their fitness performance in the natural habitat. I will also reveal the cellular and biochemical mechanisms by which NLR proteins inappropriately interact with other cellular proteins to cause hybrid - necrosis and compare the hybrid necrosis activity with pathogen induced immunity. - - 2017-08-31, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - NLRs - - - H2020-MSCA-IF-2014 - - - 655295 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 159 460,80 - - - Molecular Mechanisms Linking Psychological Stress and Ageing-Related Disease - - - EUR 159 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Ageing-related diseases are the leading causes of morbidity and mortality. A ubiquitous and potentially preventable factor predisposing to their development is psychological stress, but the molecular mechanisms underlying this - relation are largely unknown. This knowledge gap is addressed by the proposed project, which examines epigenetic modifications and, in particular, DNA methylation changes as molecular signatures that may be induced by lifetime stressors and act in - concert with advancing age to shape disease risk. The proposed fellow will first identify the DNA methylation sites that are regulated by stressors and ageing and will then examine how these epigenomic sites determine gene expression and disease - outcomes. Among key biological processes, the project will focus on immune dysregulation, a common pathogenic process for several diseases of the ageing. Immune dysregulation will be examined in the periphery but also in the brain, the orchestrator - of behavioral, neuroendocrine and immune responses. The project will engage translational approaches using both human samples and animal models, implemented via collaborations among leading institutions and experts in Europe and USA. The applicant - has unique interdisciplinary skills to carry out the project, including clinical background as well as experience in both clinical and basic research projects on the two fields brought together in the proposal, the biology of stress and - ageing-related diseases. The impact of the project can be tremendous, since elucidating the molecular mechanisms of ageing-related diseases would contribute to the development of biomarkers, targeted prevention strategies and novel treatments for - these devastating diseases. - - 2017-04-30, closed project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - STRESSAGED - - - H2020-MSCA-IF-2014 - - - 653240 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 159 460,80 - - - THz Photochemistry: Biased Proton Transfer by Ultrafast Electric Fields - - - EUR 159 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Ultraviolet or visible light induces chemical transformations via electronic excitation. Infrared radiation, corresponding to low-frequency molecular vibrations, can also bring about photochemical reactions by multi-photon - absorption. Then, how low photon energies can we reach in photochemistry? In this proposed research, I will realize a novel concept of terahertz photochemistry: activating chemical reactions with intense terahertz (THz) light of extremely low photon - energy (1 THz = 4.1 meV). - - 2017-03-31, closed project | - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - THz Photochemistry - - - H2020-MSCA-IF-2014 - - - 658467 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 159 460,80 - - - Automated synthesis of S. pneumoniae 7F capsular polysaccharide repeating unit as candidate for conjugate vaccines - - - EUR 159 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - The goal of this project is to develop an automated synthesis of the Streptococcus pneumoniae 7F capsular polysaccharide repeating unit, which is of high interest for synthetic vaccines against this pathogen. This structural - motif has never been synthesized yet, not even by traditional solution techniques. Our approach is highly innovative in the application of automated oligosaccharide synthesis, which will make the synthetic procedure more time- and cost-effective. - - - 2017-03-31, closed project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - AUTOOLIGO - - - H2020-MSCA-IF-2014 - - - 652745 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 616 050 - - - From Cloud to Star Formation - - - EUR 1 616 050 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Star Formation is a hierarchical process from the build-up of large clouds to the assembly of stars. This ERC project aims at studying the multi-scale processes of this conversion from diffuse gas to stars. The fundamental - data are provided by two PI-led large observing programs at two of the most advanced radio and mm interferometers, the Very Large Array (VLA) and the Plateau de Bure Interferometer (PdBI). This combined approach is designed to address outstanding key - questions in the field of cloud and star formation. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - CSF - - - ERC-2014-CoG - - - 648505 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 497 125 - - - Fuel from sunlight: Covalent organic frameworks as integrated platforms for photocatalytic water splitting and CO2 reduction - - - EUR 1 497 125 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - The efficient conversion of solar energy into renewable chemical fuels has been identified as one of the grand challenges facing society today and one of the major driving forces of materials innovation. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - COFLeaf - - - ERC-2014-STG - - - 639233 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 500 000 - - - Origin and Protection of Unstable Repetitive DNA Elements During Sexual Reproduction - - - EUR 1 500 000 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - The objective of this proposal is to define the molecular basis behind the origin and protection of unstable repetitive DNA sequences during sexual reproduction. Eukaryotic genomes contain large amounts of repetitive elements - that serve vital roles in cellular physiology. However, repetitive elements are intrinsically unstable, which is caused by a high likelihood for incorrect repair when DNA breaks form within repetitive elements. During sexual reproduction, numerous - DNA breaks are actively introduced into the genome, and repetitive sequences particularly threaten genome stability during this specialized developmental program. - - - 2020-04-30, ongoing project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - URDNA - - - ERC-2014-STG - - - 638197 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 609 375 - - - Unraveling the history of adaptation in an island model: Cape Verde Arabidopsis - - - EUR 1 609 375 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Islands have played a pivotal role in evolutionary theory since Darwin and Wallace. Due to their isolation, they represent natural laboratories, providing uncomplicated microcosms where fundamental principles of the - evolutionary process can be revealed. One area where island systems can provide a crucial advance is in evolutionary genetics. Here, a primary goal is to reconstruct the mechanisms, mode and tempo of the evolutionary process by identifying specific - adaptive functional variants and studying the historical dynamics of these in nature. However, even with recent advances in tools and technologies (e.g., affordable genome-wide sequencing, developments in genome manipulation), the complexity of most - natural systems makes this a challenging task. - - 2020-10-31, ongoing project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - CVI_ADAPT - - - ERC-2014-STG - - - 638810 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 499 750 - - - Quantitative analysis of Nodal/Lefty-mediated pattern formation - - - EUR 1 499 750 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - How an initially homogenous population of cells self-organizes to form patterned embryos and tissues is a long-standing mystery in the field of developmental biology. Understanding such self-organizing processes is of central - importance for regenerative medicine and would inform approaches to transform embryonic stem cells into complex multicellular structures for human tissue replacement. The influential reaction-diffusion model postulates that patterns emerge during - development under the influence of poorly diffusive activators and highly diffusive inhibitors, and we have recently found biophysical evidence supporting the differential diffusivity of the activator Nodal and its inhibitor Lefty in zebrafish - embryos. While we have begun to define the Nodal/Lefty activator-inhibitor pair as a reaction-diffusion system that can transform a uniform field of cells into an embryo, three important questions remain: First, how is the differential diffusivity of - activators and inhibitors achieved in living embryos? The molecular weights of activator and inhibitor proteins are too similar to explain the difference in diffusivities. Second, how do reaction-diffusion systems adapt to tissue size? Embryos can - vary considerably in size, but the proportions of their body plans are remarkably constant. How reaction-diffusion systems mediate this scale-invariant patterning in vivo is unknown. Third, how do reaction-diffusion systems self-organize? Embryos are - often born with maternally provided prepatterns, and it is unknown whether reaction-diffusion systems also form relevant patterns in the absence of such prepatterns. We will address these questions in zebrafish and mouse embryonic stem cells by - combining innovative quantitative experimentation and mathematical modeling. This high-risk/high-gain approach will allow us to unravel general principles underlying self-organizing processes and will inform new strategies for human tissue - engineering from embryonic stem cells. - - 2020-06-30, ongoing project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - QUANTPATTERN - - - ERC-2014-STG - - - 637840 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 499 700 - - - Dynamic Nanoplasmonics - - - EUR 1 499 700 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - The key component of nanoplasmonics is metals. When metal nanoparticles are placed in close proximity, the possibility of shaping and controlling near-field and far-field optical properties expands enormously. Near-field - coupling between metal nanoparticles is extremely sensitive to nanometer conformational changes. Such strong dependence on conformation provides unique opportunities in manipulating optical response on the nanoscale. Simultaneously, it also raises - significant challenges in realization of dynamic plasmonic systems, which can exhibit immediate conformational changes upon a regulated physical or chemical control input. - - - 2020-03-31, ongoing project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - Dynamic Nano - - - ERC-2014-STG - - - 638001 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 499 904 - - - Unraveling interstellar chemistry with broadband microwave spectroscopy and next-generation telescope arrays - - - EUR 1 499 904 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - The goal of the research program, ASTROROT, is to significantly advance the knowledge of astrochemistry by exploring its molecular complexity and by discovering new molecule classes and key chemical processes in space. So far, - mostly physical reasons were investigated for the observed variations in molecular abundances. We here propose to study the influence of chemistry on the molecular composition of the universe by combining unprecedentedly high-quality laboratory - spectroscopy and pioneering telescope observations. Array telescopes provide new observations of rotational molecular emission, leading to an urgent need for microwave spectroscopic data of exotic molecules. We will use newly developed, unique - broadband microwave spectrometers with the cold conditions of a molecular jet and the higher temperatures of a waveguide to mimic different interstellar conditions. Their key advantages are accurate transition intensities, tremendously reduced - measurement times, and unique mixture compatibility. - - - 2020-04-30, ongoing project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - ASTROROT - - - ERC-2014-STG - - - 638027 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 2 000 000 - - - Quantifying the effects of interacting nutrient cycles on terrestrial biosphere dynamics and their climate feedbacks QUINCY - - - EUR 2 000 000 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Nutrient availability plays a pivotal role in the response of terrestrial ecosystems to increasing atmospheric CO2 and climate change. The global role of nutrients is only poorly understood quantitatively, limiting the - predictive understanding of terrestrial biosphere - climate feedbacks. The first generation of global nutrient-carbon cycle models shows strongly diverging estimates of the nutrient effect, resulting from lacking integration of ecosystem observations - and fundamental uncertainties in the representation of governing processes. The objective of QUINCY is to clarify the role of the interacting terrestrial nitrogen and phosphorus cycles and their effects on terrestrial C allocation and residence times - as well as terrestrial water fluxes. QUINCY will create a novel, predictive framework founded on the principle of resource optimisation, shifting the paradigm of terrestrial biosphere modelling towards an active biological control of matter flows. - QUINCY’s main themes are (i) the effects of nutrient availability on plant photosynthesis and respiration, explicitly taking the energy requirement of nutrient acquisition into account, and (ii) the effects of vegetation-soil interactions, namely - rhizosphere processes, on plant nutrient availability and soil C turnover. To corroborate these theoretical concepts, QUINCY will synthesise existing and ongoing ecosystem monitoring and manipulation studies. To specifically test emerging hypotheses - on the effects of rhizosphere priming on soil C storage and plant nutrition - and to provide currently lacking data for soil-vegetation models - QUINCY will establish a tree mesocosm, elevated CO2 experiment. The novel model concepts will be - consistently integrated to form a new general terrestrial biosphere model. For the first time, QUINCY will be able to address the multiway interactions of carbon, nitrogen, phosphorus and water cycles globally in a theoretically well-founded way - commensurate with ecosystem observations. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - QUINCY - - - ERC-2014-CoG - - - 647204 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 500 000 - - - The mechanism of sleep control through a sleep-active sleep-promoting neuron - - - EUR 1 500 000 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Sleep is essential for human and animal life and is broadly conserved. The nervous system induces sleep through the activation of sleep-active sleep-promoting neurons but the key mechanisms of sleep control remain to be - elucidated. Recent work from my lab showed that the C. elegans nervous system contains a single sleep-active sleep-promoting neuron, called RIS, which is GABAergic and peptidergic as is its vertebrate counterpart. C. elegans shows sleep behavior and - allows the easy combination of behavioral assays with functional neural imaging and genetics. Here I propose to study the single neuron RIS as a highly simplified model of a sleep-active neuron. This is a unique and novel approach to sleep research - and my expertise on sleep behavior in C. elegans puts me into a pole position to study sleep. I will elucidate the molecular mechanism of activation of sleep-active neurons, analyze the mechanism of homeostasis of sleep-active neurons, and determine - the molecular mechanisms by which sleep-active neurons induce sleep in the nervous system. I will combine transcriptional profiling of sleep-active neurons with physiological assays such as functional neural imaging, genetic screening, optogenetics, - and functional molecular analysis of mutants. Using the highly simplified C. elegans model, I will boost sleep research and gain mechanistic insight into the regulation of sleep behavior through sleep-active neurons. This will be the first time that - sleep-active neurons have been dissected in this way and I expect to identify novel conserved molecular and circuitry mechanisms. This work should provide the basis for understanding the more complex systems that control sleep in vertebrates and for - understanding human sleep disorders. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - SLEEPCONTROL - - - ERC-2014-STG - - - 637860 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 746 038 - - - combining SYnthetic Biology and chemistry to create novel CO2-fixing enzymes, ORGanelles and ORGanisms - - - EUR 1 746 038 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Carbon dioxide (CO2) is a potent greenhouse gas whose presence in the atmosphere is a critical factor for global warming. At the same time atmospheric CO2 is a cheap and readily available carbon source that can in principle be - used for the synthesis of biomass/biofuels and value-added products. However, as synthetic chemistry lacks suitable catalysts to functionalize the CO2-molecule, there is an increasing need to exploit the CO2-fixing mechanisms offered by Nature for - applications at the interface of chemistry and biology. This proposal is centered on reductive carboxylation, a completely novel principle of enzymatic CO2-fixation that we discovered only recently and that is one of the most efficient CO2-fixation - reactions described in biology so far. First, we will focus on understanding the novel principle of reductive carboxylation, by studying its catalysis at molecular scale and single step resolution. This will allow us to derive the first detailed - catalytic framework for highly efficient CO2-fixation and enable us to engineer novel carboxylation reactions and products. Second, we will establish a new in vitro platform for the assembly and optimization of artificial ("synthetic") CO2-fixation - pathways that are based on reductive carboxylation and that have been calculated to be kinetically and bioenergetically favored compared with naturally existing CO2-fixation pathways. This platform closes a long-standing gap between the theory and - practice of synthetic pathway design, and will be used to develop the first functional in vitro module for CO2-fixation, a "synthetic organelle". Finally, we will realize synthetic CO2-fixation in selected biological model systems. To that end, we - will implement the optimized in vitro pathways in isolated chloroplasts, as well as alpha-proteobacterial hosts to create novel CO2-fixing organelles and organisms, breaking new grounds in understanding and engineering biological systems for - efficient CO2-fixation. - - 2020-04-30, ongoing project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - SYBORG - - - ERC-2014-STG - - - 637675 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 988 100 - - - Atomic-Scale Dynamics of Quantum Materials - - - EUR 1 988 100 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Quantum materials exhibit strong electron-electron interaction, which gives rise to such remarkable phenomena as high temperature superconductivity and colossal magnetoresistance. These materials mark one of the frontiers of - modern condensed matter physics: a new class of solids where many-body physics dominates. By understanding quantum materials a new generation of devices may become available, greatly boosting our ability to handle information or harvest energy. - - - 2020-05-31, ongoing project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - dasQ - - - ERC-2014-STG - - - 633818 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 148 613 - - - spim4You: customised solutions for light sheet microscopes and imaging data analysis. - - - EUR 148 613 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Biological research heavily relies on visualization of biological samples by microscopy. In recent years light-sheet microscopy has emerged as a paradigm shifting technique. Only with light sheet microscopy it is for instance - possible to follow every cell in a living system throughout development, to monitor brain activity of a live animal or to study cancer cells in their native three dimensional environment within an organism. Thus, light sheet microscopy has the - potential to revolutionize biological research and in the near future every research establishment will have a light sheet microscope. During the Hourglass ERC grant, my laboratory developed two widely used open access solutions for light sheet - microscopy: - - - 2017-04-30, closed project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2015 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Germany - - - spim4You - - - ERC-2015-PoC - - - 680901 - - - - - TEL AVIV UNIVERSITY - TEL AVIV UNIVERSITY - - - EUR 150 000 - - - Assay for cancer diagnostics by quantification of 5hmC - - - EUR 150 000 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Assay for cancer diagnostics by quantification of 5hmC - - 2019-01-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Israel - - - OR-HMC - - - ERC-2017-PoC - - - 767931 - - - - - EUROPEAN RESEARCH INFRASTRUCTURE CONSORTIUM FOR THE SURVEY OF HEALTH, AGEING AND RETIREMENT IN EUROPE - - - EUR 5 493 328 - - - Achieving world-class standards in all SHARE countries - - - EUR 5 493 328,75 - - - Germany - - - Research Organisations - - The central objective of this project is to improve European coverage, stability and cross-national comparability of SHARE, the Survey of Health, Ageing and Retirement in Europe, while a sustainable funding model will be - negotiated with the member states, DG RTD, DG JRC and several policy-related DGs to fully implement SHARE-ERIC in all SHARE countries. - - 2018-06-30, ongoing project | - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-3-2015 - Individual implementation and operation of ESFRI projects - - - RIA - Research and Innovation action - - - Germany - - - SHARE-DEV3 - - - H2020-INFRADEV-1-2015-1 - - - 676536 - - - - - FUNDACAO D. ANNA SOMMER CHAMPALIMAUD E DR. CARLOS MONTEZ CHAMPALIMAUD - - - EUR 160 635,60 - - - From surrogate hemodynamics-based fMRI towards direct functional imaging of neural activity via sensing activity-induced cell swellings and neurotransmitter releases in vivo - - - EUR 160 635,60 - - - Portugal - - - Research Organisations - - Functional-Magnetic Resonance Imaging (fMRI) has transformed our understanding of brain function due to its ability to noninvasively tag ‘active’ brain regions. Nevertheless, fMRI only detects neural activity indirectly, by - relying on slow hemodynamic couplings whose relationships with underlying neural activity are not fully known. - - - 2017-03-31, Grant Agreement terminated | - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Portugal - - - SPECIFIC fMRI - - - H2020-MSCA-IF-2014 - - - 657366 - - - - - KOBENHAVNS UNIVERSITET - UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK - SIRIUS ANALYTICAL INSTRUMENTS LTD - Pfizer Limited - PARAYTEC LIMITED - - - EUR 216 000 - - - Driving innovation in pharmaceuticals: integrated studies of physical dissolution properties of crystalline and amorphous forms using enhanced orthogonal monitoring techniques - - - EUR 216 000 - - - Denmark - Ireland - United Kingdom - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The CRYDIS exchange programme will establish and support international and inter-sectoral transfer of knowledge and expertise in pharmaceutical and instrument science between several EU research institutes and industrial - companies. It will also enhance understanding of the value of inter-sectoral exchange mechanisms for taking research to market. - - 2017-12-31, closed project | - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Denmark - - - CRYDIS - - - H2020-MSCA-RISE-2014 - - - 644056 - - - - - THE UNIVERSITY OF SHEFFIELD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - Teknologian tutkimuskeskus VTT Oy - AARHUS UNIVERSITET - LEIBNIZ-INSTITUT FUR POLYMERFORSCHUNG DRESDEN EV - UNIVERSIDADE NOVA DE LISBOA - INSTITUTO DE TECNOLOGIA QUIMICA E BIOLOGICA - UNIVERSIDADE NOVA DE LISBOA - OXFORD BIOMATERIALS LIMITED - SPINNOVA OY - - - EUR 3 741 870,25 - - - FLow Induced Phase Transitions, A new low energy paradigm for polymer processing - - - EUR 3 741 871,25 - - - United Kingdom - United Kingdom - Finland - Denmark - Germany - Portugal - Portugal - United Kingdom - Finland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Currently there is no truly sustainable pathway for the production of plastics, an industry which in the EU employs 1.45M people, has a turnover of €89B but consumes ~778GWh of energy per annum. This is an opportunity for - industry with pressure increasing to develop low energy, high-quality, wet-processing techniques for consumer products. Here Nature may provide us with inspiration, as over hundreds of millions of years, it has evolved numerous strategies for - efficient processing of its materials. One such solution has been recently hypothesised in natural silk spinning: FLIPT: FLow Induced Phase Transitions, a disruptive process which we believe could hold the key to a new low energy paradigm for polymer - processing. Our research is promising, as it has already shown that silk is at least 1000 times more efficient at processing than a standard polymer (HDPE). - - 2019-08-31, ongoing project | - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-1-2014 - FET-Open research projects - - - RIA - Research and Innovation action - - - United Kingdom - - - FLIPT - - - H2020-FETOPEN-2014-2015-RIA - - - 713475 - - - - - MUSEE ROYAL DE L'AFRIQUE CENTRALE - - - EUR 172 800 - - - Rwenzori Ice Dynamics and Environmental Changes - - - EUR 172 800 - - - Belgium - - - Research Organisations - - At the border between Uganda and the D.R. of Congo, the Rwenzoris form a remote and high-altitude mountain range stretching through the East African Rift System. With heights of 4-5 km, they include Africa's third highest peak - (Mt. Stanley, 5109 m) as well as some of the last African glaciers. The combined area of the Rwenzori glaciers declined by more than 75% during the 20th century, and halved between 1987 and 2006. This extreme mass loss may have strong implications - for the local hydrology, ecosystems and communities, and recent estimates suggest that the glaciers will disappear in the next decade(s). This trend correlates well with similarly dramatic glacier retreats on Mt Kilimandjaro (Tanzania) and Mt Kenya - (Kenya) during the same period, and is attributed to increased air temperature or reduced humidity/cloud cover. Despite recent work on the evolution of glacier extent in the last decades, the measured glacier retreat, as well as the interpretation of - the driving climatic factors responsible since the 1980’s, remain controversial and are limited to available data. - - 2017-09-06, closed project - - - 2015-09-07 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - Belgium - - - RIDEC - - - H2020-MSCA-IF-2014 - - - 656847 - - - - - UNIVERSITY COLLEGE LONDON - BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY - - - EUR 241 169,40 - - - Decoding memory processing from experimental and spontaneous human brain activity using intracranial electrophysiological recordings and machine learning based methods. - - - EUR 241 169,40 - - - United Kingdom - United States - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Despite the critical importance of memory for cognitive function and socialization, very little is known about how information is stored for later retrieval and use. Understanding how the human brain maintains and stores - information would enhance research on memory dysfunction in degenerative diseases, such as the age-related dementias, which represent a large burden for European society, and could facilitate the development of strategies for improving memory. - - 2018-11-21, ongoing project | - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - DecoMP_ECoG - - - H2020-MSCA-IF-2014 - - - 654038 - - - - - WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER - UNIVERSIDADE NOVA DE LISBOA - INSTITUTO SUPERIOR DE ESTATISTICA E GESTAO DE INFORMACAO DA UNIVERSIDADE NOVA DE LISBOA - NOVA INFORMATION MANAGEMENT SCHOOL - UNIVERSITAT JAUME I DE CASTELLON - - - EUR 3 677 229 - - - Joint Doctorate in Geoinformatics - Enabling Open Cities - - - EUR 3 677 229 - - - Germany - Portugal - Portugal - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Urbanisation has been a key trend for centuries and is expected to continue throughout the 21st century as well. Cities have to continuously strive to provide a sustainable, safe and liveable environment for their - ever-increasing populations. In recent years, the term ‘smart cities’ has been coined for initiatives that monitor and analyse different aspects of urban life, and manage service provision intelligently. A key gap in this area relates to how people - can understand the processes driving smart cities and their services, and how they can gain a sense of control rather than being controlled by the services provided by a smart city. GEO-C aims to contribute methods and tools to realise smart and open - cities, in which all groups of society can participate on all levels and benefit in many ways. The complementary strands of research in GEO-C will lead to an improved understanding of how to build open cities and will produce a prototypical open city - toolkit. The toolkit will contain software, libraries, apps and frameworks that enable cities to easily set up or adapt key services, processes and analyses. This research area provides challenging and rewarding topics for early-stage researchers to - carry out a PhD. These topics include, for example, participation across all ages and groups of society, the assessment of the quality of life, and fundamental urban services. As the 15 PhD researchers will become experts in the toolkit, their career - perspectives will benefit greatly from the toolkits’ public and open release. To further increase the impact of GEO-C and to also optimise career perspectives of the PhD researchers, the city councils of Münster, Castellón, and Lisbon and several - companies across Europe will be closely involved as associated partners. They provide input to the toolkit, host early-stage researchers, and drive the use of the toolkit and the realisation of open cities as envisioned by GEO-C. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-EJD - Marie Skłodowska-Curie Innovative Training Networks (ITN-EJD) - - - MSCA-ITN-EJD - European Joint Doctorates - - - Germany - - - GEO-C - - - H2020-MSCA-ITN-2014 - - - 642332 - - - - - FACULDADE DE CIENCIAS MEDICAS DA UNIVERSIDADE NOVA DE LISBOA - UNIVERSIDADE NOVA DE LISBOA - - - EUR 160 635,60 - - - Mechanisms of synaptic growth and plasticity - - - EUR 160 635,60 - - - Portugal - Portugal - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - My long-term goal is to understand the cellular and molecular mechanisms that govern synaptic growth and plasticity, and how dysfunction in these pathways contributes to disease. Neurons are the most morphologically diverse - cell type whose morphology determines many functional aspects of a neuronal network. The primary shape of a neuron is established during axon and dendrite outgrowth and synapse formation, but is subject to subsequent modifications by physiological - events. In response to changes in synaptic activity, neurons can alter both pre and postsynaptic elements of the synapse. Defects in synaptic morphology and in activity-dependent plasticity are a hallmark of several neurodegenerative and cognitive - disorders. It is therefore critical to know the basic mechanisms by which neurons acquire their shape and change it in response to activity, and to dissect the genes that regulate these processes. To address these questions, this proposal is divided - in the following aims: - - 2018-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Portugal - - - Neuronal Trafficking - - - H2020-MSCA-IF-2014 - - - 661543 - - - - - STOCKHOLMS UNIVERSITET - - - EUR 185 857,20 - - - Sources and atmospheric processing of carbonaceous aerosol in East Asia - - - EUR 185 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - High loading of carbonaceous aerosols from residential combustion of coal and wood fuels, traffic, industry, and biomass burning pollute the air of East Asia. The resulting Atmospheric Brown Clouds (ABC) are in wintertime - warming the atmosphere yet dimming the surface in this vast region with severe impact on the climate, food and water security as well as air quality. Although these short-lived climate pollutant (SLCP) aerosols attract large interests across the - science-policy interface, efficient mitigation actions are hampered by the limited understanding of the relative contributions of different sources of combustion-derived carbonaceous aerosols and of their subsequent atmospheric processing. Here the - relative contribution from fossil fuel and biomass combustion will be quantified by molecular combustion markers and powerful isotopic fingerprinting, including microscale-14C dating of BC and OC aerosols. Aerosol samples will be probed from recently - established Sino-Swedish observational program in the four populated and industrialization hotspots in China (North China Plain – Beijing; Yangtze River Delta – Shanghai; Pearl River Delta – Guangzhou; Szechuan Basin– Chengdu) and from the SE Yellow - Sea recipient site on a Jeju Island (Korea Climate Observatory – Gosan), providing an ideal context for these investigations. The molecular/isotopic fingerprints of such synoptic aerosol samples provide integrated source signature and possibility to - assess atmospheric processing during over-ocean long-range transport. This field quantification of BC and OC sources and processing in E Asia will contribute to (a) top-down observation-based test and improvement of bottom-up technology-based - emission inventories (uncertain for small-scale and open combustion); (b) improved aerosol parameterization in climate and air quality models, and (c) scientific underpinning for policy makers to make efficient mitigation actions toward decreasing - anthropogenic aerosol emissions. - - 2017-04-30, closed project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - EastAsiaAerosol - - - H2020-MSCA-IF-2014 - - - 659529 - - - - - UNIVERSIDADE DA BEIRA INTERIOR - BRUNEL UNIVERSITY LONDON - POLITECHNIKA SLASKA - ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA - UNIVERSIDAD DE GRANADA - UNIVERSITY OF STRATHCLYDE - ALSITEK LIMITED - SOFALCA SOCIEDADE CENTRAL DE PRODUTOS DE CORTICA LIMITADA - BEIRA SERRA - ASSOCIACAO PROMOTORADO DESENVOLVIMENTO RURAL INTEGRADO - Refractarios ALFRAN, S.A. - - - EUR 567 000 - - - Reuse of mining waste into innovative geopolymeric-based structural panels, precast, ready mixes and insitu applications - - - EUR 567 000 - - - Portugal - United Kingdom - Poland - Italy - Spain - United Kingdom - United Kingdom - Portugal - Portugal - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The construction sector, currently in crises in some countries due to the economic development model adopted during last decades, can again play an important role for the European economy to be more innovative by using fewer - resources (raw materials and energy) and reducing environmental impact (emission of greenhouse gases and dust pollution). Access to raw materials and resource efficiency are at the forefront of the EU political debate and recycling is a main part of - the solution of many strategic objectives. It addresses resource scarcity and enhances security of material supply, while contributing to higher energy efficiency and lower environmental impacts. Moreover, recycling offers significant investment, - innovation and employment opportunities in the EU. In this context, this RISE programme aims to promote international and inter-sector collaboration through research and innovation staff exchanges, share knowledge and ideas from research to market - (and vice-versa) for the advancement of science and the development of innovation within the recycling and valorization of mining and quarrying wastes which represent 27% of the EU total waste generated from economic activities and households, - promote utilization of innovative geopolymeric materials in the construction sector, and foster a shared culture of research and innovation that welcomes and rewards creativity and entrepreneurship and helps turn creative ideas into innovative - products, services or processes in the materials industry through recycling mining wastes, by taking advantage of the integrated knowledge acquired in the complementary areas of the RISE partners. In this scenario, this RISE action aims at taking - advantage of the recent developments in the areas of materials science, processing engineering, structural engineering, infrastructure systems, arts and design and market perspectives, turning mining waste into valuable materials for infrastructure - and building products. - - 2018-12-31, ongoing project | - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Portugal - - - REMINE - - - H2020-MSCA-RISE-2014 - - - 645696 - - - - - UNIVERSIDADE NOVA DE LISBOA - FACULDADE DE CIENCIAS SOCIAIS E HUMANAS DA UNIVERSIDADE NOVA DE LISBOA - - - EUR 160 635,60 - - - QUANTIFYING THE IMPACT OF TRANSPORT INFRASTRUCTURES:NETWORK ANALYSIS APPLIED TO THE DIACHRONICALLY STUDYOF THE IBERIAN PENINSULA (From Roman Times to XIXth Century) - - - EUR 160 635,60 - - - Portugal - Portugal - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The impact of the transport infrastructures in the development of countries and territories is one of the most current topics in the European policies. The Mercator-e project is designed to analyse the diachronic social, - political and economical repercussions of the transport infrastructures during several periods of the Iberian Peninsula. An integrated approach joining multi-proxy analysis (SNA applied to the network centrality, TNA to analyse transport costs & - times, demography studies) and the study of archaeo-historical sources will be applied. Analysing the transport communication networks in various time scopes will offer to the academic society new quantified data about the infrastructures morphology - and their impact in the political and economical evolution of these territories. Historically, the Iberian Peninsula has had periods with very different political ideologies about the role and needs of infrastructure that will be analysed in this - project: 1) The Roman era, 2) The Middle Ages, 3) the Modern Era, and 4) The XIXth Century and the emergence of the railroad. - - 2018-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Portugal - - - Mercator-e - - - H2020-MSCA-IF-2015 - - - 706260 - - - - - UNIVERSIDADE NOVA DE LISBOA - FACULDADE DE CIENCIAS SOCIAIS E HUMANAS DA UNIVERSIDADE NOVA DE LISBOA - - - EUR 160 635,60 - - - Analysis of the Artistic Exchanges in the Medieval Mediterranean between 12th and 15th Centuries through the Geographical Information Systems (GIS): A Critical Review of Centre and Peripheries - - - EUR 160 635,60 - - - Portugal - Portugal - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The aim of this research project is to evaluate the artistic exchanges in the Mediterranean during the late Middle Ages through the Geographical Information Systems (GIS). The start point is the selection of certain elements - of the Islamic art, developed by the Almoravids in the 12th century. It is assumed that Almoravid arts and architecture were not isolated and can be related to other Mediterranean artistic manifestations due to commercial, political and cultural - relations. In this context, the objectives of the project are: to measure the presence of the pre-selected elements in the main artistic manifestations of the Islamic and Christian Mediterranean countries in the late Middle Ages, to apply the new - method based on the GIS, through the creation of three databases for studying the exchanges between the main Mediterranean artistic manifestations and Almoravid art, to assess the relation of religion and power with the artistic productions of the - Islamic countries in the Mediterranean frame and to review the concepts of centre and peripheries regarding the artistic production in the Mediterranean context. - - 2018-05-31, ongoing project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Portugal - - - ArtMedGIS - - - H2020-MSCA-IF-2015 - - - 699818 - - - - - KONINKLIJKE STERRENWACHT VAN BELGIE - KONINKLIJKE STERRENWACHT VAN BELGIE - - - EUR 2 500 000 - - - Rotation and Nutation of a wobbly Earth - - - EUR 2 500 000 - - - Belgium - Belgium - - - Research Organisations - Research Organisations - - The rotation of the Earth has long been used as a measure of time, and the stars as reference points to determine travellers’ whereabouts on the globe. Today, precise timescales are provided using atomic clocks and precise - positioning is determined using geodetic techniques such as GPS grounded on two reference frames: the terrestrial frame, fixed relative to the Earth and rotating synchronously with the planet, and the celestial frame, which is immobile in space, - where the artificial satellites such as those of GPS are moving. The relationship between these frames is complicated by the fact that the rotation and orientation of the Earth is subject to irregularities induced by global mass redistributions with - time and external forcing such as the gravitational pull of the Sun and the Moon. With the advance of observation precision, the causes of Earth orientation changes are progressively being identified by geodesists and geophysicists. The term - ‘precession’ describes the long-term trend of the orientation of the axis of spin, while ‘nutation’ is the name given to shorter-term periodic variations, which are the prime focus of the present project. The rotation axis of the Earth is moving in - space at the level of 1.5km/year due to precession and has periodic variations at the level of 600 meters as seen from space in a plane tangent to the pole. The present observations allow scientists to measure these at the sub-centimetre level - enabling them to identify further physics of the Earth’s interior to be taken into account in the Earth orientation models such as the coupling mechanisms at the boundary between the liquid core and the viscoelastic mantle, as well as many other - factors (sometimes not yet definitely identified). The proposed research will address many of these and will result in the development of improved global orientation of the Earth with an unprecedented accuracy - at the sub-centimetre level. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Belgium - - - RotaNut - - - ERC-2014-ADG - - - 670874 - - - - - UNIVERSIDADE NOVA DE LISBOA - INSTITUTO DE TECNOLOGIA QUIMICA E BIOLOGICA - UNIVERSIDADE NOVA DE LISBOA - UNIVERSIDADE NOVA DE LISBOA - INSTITUTO DE TECNOLOGIA QUIMICA E BIOLOGICA - UNIVERSIDADE NOVA DE LISBOA - - - EUR 1 795 967,50 - - - Development of biomaterials through mimesis of plant defensive interfaces to fight wound infections - - - EUR 1 795 967,50 - - - Portugal - Portugal - Portugal - Portugal - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Fighting microbial infection of wounds, especially in immunocompromised patients, is a major challenge in the 21st century. The skin barrier is the primary defence against microbial (opportunistic) pathogens. When this barrier - is breached even non-pathogenic fungi may cause devastating infections, most of which provoked by crossover fungi able to infect both plant and humans. Hence, diabetic patients (ca. 6.4% of the world population), who are prone to develop chronic - non-healing wounds, constitute a major risk group. My research is driven by the vision of mimicking the functionality of plant polyesters to develop wound dressing biomaterials that combine antimicrobial and skin regeneration properties. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Portugal - - - MIMESIS - - - ERC-2014-CoG - - - 647928 - - - - - UNIVERSITAET LEIPZIG - UNIVERSITAET LEIPZIG - - - EUR 1 498 620 - - - ECOSYSTEM RESPONSES TO EXOTIC EARTHWORM INVASION IN NORTHERN NORTH AMERICAN FORESTS - - - EUR 1 498 620 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Earth is experiencing substantial biodiversity losses at the global scale, while both species gains and losses are occurring locally and regionally. Nonrandom changes in species distributions could profoundly influence - ecosystem functions and services. However, few experimental tests have examined the influences of invasive ecosystem engineers, which can have disproportionally strong impacts on native ecosystems. Invasive earthworms are a prime example of ecosystem - engineers that influence many ecosystems around the world. In particular, European earthworms invading northern North American forests may cause simultaneous species gains and losses with significant consequences for essential ecosystem processes - like nutrient cycling and crucial services like carbon sequestration. Using a synthetic combination of field observations, field experiments, lab experiments, and meta-analyses, the proposed work will be the first systematic examination of earthworm - effects on relationships between plant communities, soil food webs, and ecosystem processes. Further, effects of a changing climate on the spread and consequences of earthworm invasion will be investigated. Meta-analyses will be used to test if - earthworms cause invasion waves, invasion meltdowns, habitat homogenization, and ecosystem state shifts. Global data will be synthesized to test if the relative magnitude of effects differ from place to place depending on the functional dissimilarity - between native soil fauna and exotic earthworms. Moving from local to global scale, the present proposal examines the influence of earthworm invasions on biodiversity–ecosystem functioning relationships from an aboveground–belowground perspective. - This approach is highly innovative as it utilizes exotic earthworms as an exciting model system that links invasion biology with trait-based community ecology, global change research, and ecosystem ecology, pioneering a new generation of - biodiversity–ecosystem function research. - - 2021-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - ECOWORM - - - ERC-2015-STG - - - 677232 - - - - - KUNGLIGA TEKNISKA HOEGSKOLAN - KUNGLIGA TEKNISKA HOEGSKOLAN - - - EUR 2 000 000 - - - Boundary value problems for nonlinear integrable equations - - - EUR 2 000 000 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The purpose of this project is to develop new methods for solving boundary value problems (BVPs) for nonlinear integrable partial differential equations (PDEs). Integrable PDEs can be analyzed by means of the Inverse - Scattering Transform, whose introduction was one of the most important developments in the theory of nonlinear PDEs in the 20th century. Until the 1990s the inverse scattering methodology was pursued almost entirely for pure initial-value problems. - However, in many laboratory and field situations, the solution is generated by what corresponds to the imposition of boundary conditions rather than initial conditions. Thus, an understanding of BVPs is crucial. - - - 2021-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Sweden - - - BOPNIE - - - ERC-2015-CoG - - - 682537 - - - - - UNIVERSIDADE NOVA DE LISBOA - FACULDADE DE CIENCIAS SOCIAIS E HUMANAS DA UNIVERSIDADE NOVA DE LISBOA - - - EUR 234 448,20 - - - The Profanation of Opera: Music and Drama on Film - - - EUR 234 448,20 - - - Portugal - Portugal - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The project PROPERA (The Profanation of Opera: Music and Drama on Film) aims to shed new light on the relationship between opera and film. It draws on the hypothesis that the mediation of film displaces, broadens, and enriches - our experience and understanding of opera in ways that have not yet been fully explored in their aesthetic and political potential. To fill this gap, the proposed research on the interplay between the two genres and media over the last hundred years - will focus on a variety of objects including not only opera-films, but also feature- and short-length mainstream and experimental movies that incorporate opera in relevant and thought-provoking ways. The ultimate goal of looking at opera through the - lens of film is to develop and refine a “profane” approach to a “sacred” genre – that is, to challenge the identification of opera as a live performance art belonging to an inherently conservative tradition so as to reimagine the past, present, and - future of the operatic genre in a media-saturated world. Based on an interdisciplinary approach at the crossroads of opera and film studies, musicology, and philosophy, the consequences of this shift of perspective will be explored from the - standpoint of production and spectatorship, with regard to traditional and contemporary repertoire alike. Globally seen, the project – to be carried out at the University of Chicago and the Universidade Nova de Lisboa, but involving several - non-academic institutions – also seeks to create bridges between scholarly research, artistic practice and public engagement. The outcomes include 1 monograph, at least 6 articles, 3 workshops, 1 international conference, 1 festival, 1 conference - series, 1 collaborative on-line platform, and 1 international network on opera, film and new media. If successful, the project will have a considerable impact on the scientific career of the candidate and strongly contribute to the - internationalization of the host institution. - - 2020-02-29, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Portugal - - - PROPERA - - - H2020-MSCA-IF-2015 - - - 708601 - - - - - ISTITUTO NAZIONALE DI FISICA NUCLEARE - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - UNIVERSITE BLAISE PASCAL CLERMONT-FERRAND II - UNIVERSITE CLERMONT AUVERGNE - UNIVERSITE CATHOLIQUE DE LOUVAIN - LABORATORIO DE INSTRUMENTACAO E FISICA EXPERIMENTAL DE PARTICULAS - INSTITUTE OF ACCELERATING SYSTEMS AND APPLICATIONS - UNIVERSITA DEGLI STUDI DI PADOVA - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH - TECHNISCHE UNIVERSITAET MUENCHEN - - - EUR 2 402 451,84 - - - Advanced Multi-Variate Analysis for New Physics Searches at the LHC - - - EUR 2 402 452,42 - - - Italy - United Kingdom - France - France - Belgium - Portugal - Greece - Italy - Switzerland - Germany - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - - With the 2012 discovery of the Higgs boson at the Large Hadron Collider, LHC, the Standard Model of particle physics has been completed, emerging as a most successful description of matter at the smallest distance scales. But - as is always the case, the observation of this particle has also heralded the dawn of a new era in the field: particle physics is now turning to the mysteries posed by the presence of dark matter in the universe, as well as the very existence of the - Higgs. The upcoming run of the LHC at 13 TeV will probe possible answers to both issues, providing detailed measurements of the properties of the Higgs and extending significantly the sensitivity to new phenomena. - - - 2019-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Italy - - - AMVA4NewPhysics - - - H2020-MSCA-ITN-2015 - - - 675440 - - - - - HEINRICH-HEINE-UNIVERSITAET DUESSELDORF - - - EUR 159 460,80 - - - Epidermal growth factor receptor (EGFR) activation by cytohesins - Structural Insights - - - EUR 159 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - The epidermal growth factor receptor (EGFR) is a key player in many biological responses and its aberrant function is associated with numerous diseases, including a number of cancers. Despite the significant benefits of - anti-EGFR agents in some tumours, many challenges remain in the improvement of EGFR-targeted therapies. - - 2017-05-03, closed project | - - - 2015-05-04 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - EGFR-Activ - - - H2020-MSCA-IF-2014 - - - 660258 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 159 460,80 - - - Decoding the DNA damage signalling in C. elegans by proteomic analyses of ADP-ribosylation - - - EUR 159 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Preservation of genome integrity and stability is critical for survival and propagation of individuals and species. Organisms have thus evolved rapid and efficient mechanisms -collectively termed the DNA damage response (DDR)- - to combat threats posed by DNA damage. Among these, the post-translational modification (PTM) ADP-ribosylation (ADPR) plays a decisive role in effective DDR. Although much is known about the relevance of ADPR upon DNA injury, the underlying molecular - mechanisms are still poorly understood and no systematic, unbiased proteome-wide study to determine ADPR targets in vivo has been conducted to date. The most challenging and innovative goal of this proposal is to profile in vivo ADP-ribosylated - peptides during DDR in the well-established model system Caenorhabditis elegans by the combined application of advanced proteomic approaches. I will develop novel enrichment strategies that will allow me to confidently map for the first time all the - sites of ADPR throughout the C. elegans proteome. I will take advantage of SILAN technology, which allows stable isotope labelling in C. elegans, to determine the quantitative profiles of thousands of ADPR sites during DDR. By bioinformatic analysis, - I will select candidate proteins for further investigation of the biological role of DNA damage-induced ADPR. I will then test the biological impact of ADPR of these candidates through site-specific mutation of their identified modification sites. - Finally, I will perform biochemical, molecular and functional experiments to study how ADPR alters the activity of these proteins and thereby characterize the mode of ADPR action. Understanding the regulatory networks that underlie such a complex - biological process at the organism level will provide new insights for improved treatment of DNA damage-related diseases including cancer. This is an ambitious, innovative, cross-disciplinary project at the forefront of two exciting fields, biology - and proteomics. - - 2018-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - InVivo_DDR_ADPR - - - H2020-MSCA-IF-2014 - - - 657501 - - - - - KOBENHAVNS UNIVERSITET - HELMHOLTZ ZENTRUM POTSDAM DEUTSCHESGEOFORSCHUNGSZENTRUM GFZ - UNIVERSIDAD DE SALAMANCA - UNIVERSITY COLLEGE LONDON - ARCADIS GERMANY GMBH - ARCADIS DEUTSCHLAND GMBH ADE - KARLSRUHER INSTITUT FUER TECHNOLOGIE - AMPHOS 21 CONSULTING SL - HASKOLI ISLANDS - NIRAS RADGIVENDE INGENIORER OG PLANLAEGGERE AS - REGION HOVEDSTADEN - AECOM URS ESPANA SLU - - - EUR 3 716 533,44 - - - Metal oxide Aided Subsurface Remediation: From Invention to Injection - - - EUR 3 716 533,44 - - - Denmark - Germany - Spain - United Kingdom - Germany - Germany - Germany - Spain - Iceland - Denmark - Denmark - Spain - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Thousands of sites across Europe are polluted with toxic metals and organic solvents; many more exist worldwide. As EU population grows, clean water will determine the quality of life and economic stability. Most sites remain - contaminated because existing technology is costly and disruptive. Society needs an innovative way to decontaminate soil and groundwater directly underground. In METAL-AID, we will develop new technologies through fundamental knowledge. - - 2020-06-30, ongoing project - - - 2016-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Denmark - - - METAL-AID - - - H2020-MSCA-ITN-2015 - - - 675219 - - - - - UNIVERSITY OF HAIFA - UNIVERSITY OF HAIFA - - - EUR 1 445 151 - - - Crisis on the margins of the Byzantine Empire: A bio-archaeological project on resilience and collapse in early Christian development of the Negev Desert - - - EUR 1 445 151 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project proposes an innovative, integrative and data-intensive approach to understand the parameters for long-term sustainable functioning of complex societies under vulnerable conditions. The broad aim of the research is - to explore contexts of collapse and resilience in an ancient society with high levels of socio-political complexity and technological ingenuity within a resource-limited environment. It focuses on the Byzantine early Christian urban centres of the - Negev Desert (4th-7th cent. AD) disclosing both the triumph of human ingenuity in conquering the desert through large-scale human settlement and agricultural development as well as a striking and as yet ambiguous case of wholesale systemic collapse. - To test hypotheses regarding social disintegration, economic stress, environmental degradation due to climatic or anthropogenic causes, and the question of plague the project integrates approaches in the archaeology of households, landscapes and - garbage through use of biomolecular, botanical, zoological, geological, chronometric, artifactual and contextual sources of data. - - - 2020-08-31, ongoing project | - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Israel - - - NEGEVBYZ - - - ERC-2014-CoG - - - 648427 - - - - - UNIVERSITA DEGLI STUDI DI PARMA - SABIC PETROCHEMICALS BV - - - EUR 513 435,60 - - - SUPRAmolecular polyolefins as oxygen BARRIER materials - - - EUR 513 435,60 - - - Italy - Netherlands - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The production of the next generation of oxygen-barrier polyolefins materials capable of meeting the current and future demands of society in a sustainable manner will require both new technologies and highly trained - scientists. Supramolecular chemistry provides a powerful approach to develop new materials with emerging properties, such as low permeability to oxygen, maintaining easy processing. The SUPRABARRIER EID ITN will train a new generation of European - scientists with the skills necessary to overcome such future demands and simultaneously develop new strategies for the production of new polymeric systems, which greatly impact important fields such as food and medical packaging. The EID proponents - are experts in the areas of supramolecular chemistry and polymer production. Expertise of the partners encompasses the general areas of supramolecular and polymer chemistry, with individual research competencies focusing on a number of specific - themes including non-covalent chemistry, supramolecular interactions, polymer blending, polymer processing, polymer production, and Life Cycle Assessment (LCA) analysis and characterisation techniques of complex polymeric and self-assembled - materials. The complementarity and diversity realized in synthesis, analysis, development, production and applications is crucial for successful research, innovation and training in this area. The partner from the private sector will extend the - fellows’ training beyond that of traditional academic settings, in particular he will have the critical role of bridging fundamental science with application and commercialisation of the results. Our activities will thus possess both breadth and - quality that can only be achieved through an interdisciplinary Academy/Industrial European effort. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-EID - Marie Skłodowska-Curie Innovative Training Networks (ITN-EID) - - - MSCA-ITN-EID - European Industrial Doctorates - - - Italy - - - SUPRABARRIER - - - H2020-MSCA-ITN-2014 - - - 642929 - - - - - UNIVERSITY COLLEGE LONDON - UNIVERSITY COLLEGE LONDON - - - EUR 139 454 - - - ExoData: a commercially supported space telescope - - - EUR 139 454 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - ExoData will use results from the very successfull ExoMol Advanced Award which created comprehensive spectroscopic line lists to help understand and model the atmospheres of exoplanets. ExoData will help build and fund a - satellite aimed at characterising exoplanet atmospheres using a cheap, agile, low earth orbit satellite mission with a launch date this decade. This mission will be part funded by the sale of telescope data to interested international clients. This - is a new business model for astonomical satellites. ExoData will (a) fund business development in partnership with a small company created to sell telescope and other data from this mission and (b) use the results of the ExoMol project to model - results from this mission and to create software and models that have potential re-sale value. The deliverable will be funded space mission and a novel business model. - - 2017-04-30, closed project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2015 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - ExoData - - - ERC-2015-PoC - - - 693297 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 246 668,40 - - - Fractionalized quantum matter: Characterization, realization and generalization - - - EUR 246 668,40 - - - France - United Kingdom - - - Research Organisations - Higher or Secondary Education Establishments - - With the advent of topological phases, we have recently witnessed a revolution in our understanding of different phases of matter. They are described by tools borrowed from mathematical topology, unlike more familiar phases - such as (ferro)magnets, classified in terms of symmetry breaking. Within these topological phases, fractionalized states of matter are of the most exotic, intriguing and potentially useful kind. They result from the delicate interplay between strong - correlations among its constituents and the topological nature of the parent non-interacting state. They carry fractional quantum numbers and topologically protected excitations, insensitive to local system details (e.g. impurities) and key to - efficient, fault-tolerant quantum computation. The fractional quantum Hall effect (FQHE) is still the hallmark of such phases but it needs strong magnetic fields and low temperatures to be realized, severely constraining the latter groundbreaking - scientific leap. - - 2018-11-01, ongoing project - - - 2015-11-02 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - France - - - Fractional - - - H2020-MSCA-IF-2014 - - - 653846 - - - - - THE UNIVERSITY OF BIRMINGHAM - UNIVERSITAET LEIPZIG - STIFTUNG DEUTSCHE GEISTESWISSENSCHAFTLICHE INSTITUTE IM AUSLAND - DGIA - UNIVERSITE DE ROUEN NORMANDIE - LATVIJAS UNIVERSITATE - UNIWERSYTET SLASKI - KLAIPEDOS UNIVERSITETAS - UNIVERSITATSMEDIZIN GREIFSWALD KORPERSCHAFT DES OFFENTLICHEN RECHTS - UNIVERZITA JANA EVANGELISTY PURKYNE V USTI NAD LABEM - LUDWIG BOLTZMANN GESELLSCHAFT OSTERREICHISCHE VEREINIGUNG ZUR FORDERUNG DER WISSENSCHAFTLICHEN FORSCHUNG - STICHTING REINIER VAN ARKEL - UNIVERSITAET AUGSBURG - - - EUR 3 729 290,40 - - - Children Born of War - Past, Present and Future - - - EUR 3 729 290,65 - - - United Kingdom - Germany - Germany - France - Latvia - Poland - Lithuania - Germany - Czech Republic - Austria - Netherlands - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Other - Higher or Secondary Education Establishments - - The physical and psychosocial impact of armed conflict on children is immense and particularly so, if these children are associated with the enemy. Overwhelming evidence suggests that children born of war (CBOW), i.e. children - fathered by foreign soldiers and born to local mothers have been and continue to be a major obstacle to successful integration of both their mothers and themselves into post-conflict societies. At a global level, previous UN studies have further - emphasized the lack of research on children born out of forced pregnancies in armed conflict. The proposed network addresses the described shortcomings by advancing the knowledge base through systematic analysis of lived experiences of CBOW in a - variety of 20th century conflict and post-conflict situations. - - - 2019-02-28, ongoing project - - - 2015-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - CHIBOW - - - H2020-MSCA-ITN-2014 - - - 642571 - - - - - ISTITUTO NAZIONALE DI GEOFISICA E VULCANOLOGIA - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - HELMHOLTZ ZENTRUM POTSDAM DEUTSCHESGEOFORSCHUNGSZENTRUM GFZ - Eidgenössische Technische Hochschule Zürich - UNIVERSITETET I BERGEN - NATURAL ENVIRONMENT RESEARCH COUNCIL - KONINKLIJK NEDERLANDS METEOROLOGISCH INSTITUUT-KNMI - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - VEDURSTOFA ISLANDS - Instytut Geofizyki Polskiej Akademii Nauk - NATIONAL OBSERVATORY OF ATHENS - INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA PAMANTULUI - UNIVERSIDADE DA BEIRA INTERIOR - GEOFYZIKALNI USTAV AV CR, V.V.I. - UNIVERSITEIT UTRECHT - BOGAZICI UNIVERSITESI - COMMUNICATIONS, CLIMATE ACTION AND ENVIRONMENTS - KOBENHAVNS UNIVERSITET - UPPSALA UNIVERSITET - STICHTING ORFEUS - HELSINGIN YLIOPISTO - Euro-Mediterranean Seismological Centre - BUREAU DE RECHERCHES GEOLOGIQUES ET MINIERES - CONSIGLIO NAZIONALE DELLE RICERCHE - KONINKLIJKE STERRENWACHT VAN BELGIE - OULUN YLIOPISTO - FOLDMERESI ES TAVERZEKELESI INTEZET - VYZKUMNY USTAV GEODETICKY TOPOGRAFICKY A KARTOGRAFICKY VVI*RESEARCH INSTITUTE OF GEODESY TOPOGRAPHY AND CARTOGRAPHY VUGTK - AMRA - ANALISI E MONITORAGGIO DEL RISCHIO AMBIENTALE SCARL - ARISTOTELIO PANEPISTIMIO THESSALONIKIS - CENTRO EUROPEO DI FORMAZIONE E RICERCA IN INGEGNERIA SISMICA - Geological Survey of Denmark and Greenland - OBSERVATORIO DEL EBRO FUNDACION - INSTITUT NATIONAL DE L ENVIRONNEMENT ET DES RISQUES INERIS - UNIVERSITA DEGLI STUDI ROMA TRE - ETHNIKO KENTRO VIOSIMIS KAI AEIFOROU ANAPTYXIS - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - LULEA TEKNISKA UNIVERSITET - ZNANSTVENORAZISKOVALNI CENTER SLOVENSKE AKADEMIJE ZNANOSTI IN UMETNOSTI - Istituto Superiore per la Protezione e la Ricerca Ambientale - THE UNIVERSITY OF LIVERPOOL - UNIVERSITY OF KEELE - ILMATIETEEN LAITOS - AKADEMIA GORNICZO-HUTNICZA IM. STANISLAWA STASZICA W KRAKOWIE - UNIVERSITY OF LEEDS - BASBAKANLIK AFET VE ACIL DURUM YONETIMI BASKANLIGI - INSTITOUTO GEOLOGIKON KAI METALLEFTIKON EREVNON - TRUST-IT SERVICES LIMITED - - - EUR 18 374 344 - - - EPOS Implementation Phase - - - EUR 31 030 832,46 - - - Italy - France - Germany - Switzerland - Norway - United Kingdom - Netherlands - Spain - Iceland - Poland - Greece - Romania - Portugal - Czech Republic - Netherlands - Turkey - Ireland - Denmark - Sweden - Netherlands - Finland - France - France - Italy - Belgium - Finland - Hungary - Czech Republic - Italy - Greece - Italy - Denmark - Spain - France - Italy - Greece - Germany - Sweden - Slovenia - Italy - United Kingdom - United Kingdom - Finland - Poland - United Kingdom - Turkey - Greece - United Kingdom - - - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Other - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The nations of Europe are distributed around some of the most complex and dynamic geological systems on the planet and understanding these is essential to the security of livelihoods and economic power of Europeans. Many of - the solutions to the grand challenges in the geosciences have been led by European scientists – the understanding of stratigraphy (the timing and distribution of layers of sediment on Earth) and the discovery of the concept of plate tectonics being - among the most significant. Our ability to monitor the Earth is rapidly evolving through development of new sensor technology, both on- and below-ground and from outer space; we are able to deliver this information with increasing rapidity, integrate - it, provide solutions to geological understanding and furnish essential information for decision makers. - - - 2019-09-30, ongoing project | - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-3-2015 - Individual implementation and operation of ESFRI projects - - - RIA - Research and Innovation action - - - Italy - - - EPOS IP - - - H2020-INFRADEV-1-2015-1 - - - 676564 - - - - - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH - - - EUR 175 419,60 - - - Higher-loop amplitudes on the sphere: a new approach to the perturbative expansion of quantum field theories - - - EUR 175 419,60 - - - Switzerland - - - Research Organisations - - Almost all we know about particle physics and the Standard Model comes from scattering experiments and our ability to predict them via scattering amplitudes (these measure probabilities of scattering processes). To meet the - impressive technological advances of particle colliders like the Large Hadron Collider at CERN, new tools and concepts have emerged over the last 25 years. More than giving methods, they have triggered a revolution in our understanding of the formal - microscopic structure of particle physics, a subject people thought they knew everything about. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - NewLoops - - - H2020-MSCA-IF-2016 - - - 749793 - - - - - THE SCOTTISH ASSOCIATION FOR MARINESCIENCE LBG - FRIEDRICH-SCHILLER-UNIVERSITAT JENA - UNIVERSITAT KONSTANZ - OSTRAVSKA UNIVERZITA - A4F ALGAFUEL SA - VIB - UNIVERSITEIT GENT - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - PROVIRON HOLDING NV - APPLIED MATHS NV - - - EUR 3 794 115,24 - - - The Algal Microbiome: Friends and Foes - - - EUR 3 794 115,24 - - - United Kingdom - Germany - Germany - Czech Republic - Portugal - Belgium - Belgium - France - Belgium - Belgium - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Algal aquaculture is developing exponentially worldwide, with multiple applications in the food, chemical and pharmaceutical industries. Current research in algal biotechnology mostly focuses on metabolite discovery, - aquaculture yield improvement and engineering bottlenecks. However, agronomical experience shows that controlling the interaction of land crops with mutualistic or pathogenic microbes is most critical to successful production. Likewise, controlling - the microbial flora associated with algae (the 'algal microbiome') is emerging as the biggest biological challenge for their increased usage. Bacteria can control the morphogenesis of algae, while others are indispensable to algal survival. Pathogens - are causing devastating diseases, the impact of which worsens with the intensification of aquaculture practices. Thus, the overarching aim of ALFF is to train 15 ESRs (researchers and technologists) within a multinational consortium, whilst bringing - a scientific step-change in our understanding of these interactions, leading to the development of superior mass algal cultivation and biocontrol strategies. ALFF tackles: 1) the identification, taxonomy and utilisation of naturally-occurring algal - symbionts and pathogens; 2) inter- and intra-species signalling and chemical ecology in aquaculture, natural environment and simplified systems (i.e. axenic cultures +/- symbionts); 3) and harnesses state of the art genomics, molecular, and - biochemical techniques to characterise these interactions. A highly interdisciplinary team underpins an ambitious theoretical, field, hands-on training and research program. With the support of high profile institutions, ALFF foresees an - exceptionally broad range of dissemination and outreach initiatives to help policy makers and the general public better understand the opportunities and issues relating to the sustainable use of our aquatic freshwater and marine resources, within and - beyond the EU. - - 2018-12-31, ongoing project | - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - ALFF - - - H2020-MSCA-ITN-2014 - - - 642575 - - - - - UNIVERSITEIT UTRECHT - - - EUR 165 598,80 - - - Shifting political power: the nature and consequences of distributed renewable energy transitions - - - EUR 165 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Global energy transitions are progressing rapidly. Over half of new generation capacity in 2014 came from renewable energy. Individual, community and co-operative decentralized renewable energy (DRE) producers are capturing a - growing share of energy markets (e.g. solar, wind, biomass). As their market share increases, DRE producers are becoming increasingly effective political actors. The traditional political privilege enjoyed by incumbent industries is challenged by - these DRE actors as they shift control over jobs, economic growth and energy supplies. Political struggles between competing interests are increasing. However, the nature and extent of these power shifts (e.g. changes in access to policy makers, - media influence), and their consequences for political systems and their outcomes (e.g. contested carbon targets, renewable energy subsidies) are poorly understood. This project addresses how and why DRE transitions are shifting political power - relations, and the consequences of those shifts for political systems and outcomes. Using an interdisciplinary approach grounded in theory on sustainability transitions (i.e. Multi-Level Perspective), power (e.g. Lukes, Foucault) and institutions - (i.e. institutional logics) the project will: (1) examine the conditions leading to shifts in political power by analyzing existing political power relations in regimes where DRE transitions are expected, occurring, or stalled; (2) assess the - mechanisms by which political power shifts resulting from these DRE transitions are occurring; and, (3) identify the consequences of DRE-related political power shifts for political systems and their outcomes. Objectives will be explored using a - global survey of 20 DRE regimes. Survey insights will be expanded in 5 international comparative cases. Findings will address urgent questions highlighted by academics, the EU, and global economic bodies about the political, economic and social - impacts of the changing energy landscape. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - POWERSHIFTS - - - H2020-MSCA-IF-2016 - - - 751843 - - - - - FACULDADE DE CIENCIAS MEDICAS DA UNIVERSIDADE NOVA DE LISBOA - UNIVERSIDADE NOVA DE LISBOA - FACULDADE DE CIENCIAS MEDICAS DA UNIVERSIDADE NOVA DE LISBOA - UNIVERSIDADE NOVA DE LISBOA - - - EUR 147 500 - - - Epithelial resistance modulation to treat disease - - - EUR 147 500 - - - Portugal - Portugal - Portugal - Portugal - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Epithelial barriers are essential for organism’s homeostasis and survival. Defects in resistance of body barrier epithelial tissues and their repair are thought to underlie a range of diseases, which affect millions. Antonio - Jacinto’s group has discovered that Septate/Tight Junctions are essential for epithelial repair. These cell-cell junctions can be potentially targeted by candidate compounds that have been identified by Thelial, a Start-Up that will collaborate in - this project. In EMODI we will complete preclinical proof of concept of the potential therapeutic activity of two selected compounds, relying on scientific results and technologies developed under ERC starting grant awarded to Dr. Antonio Jacinto. - Regarding clinical application, we will focus on rare (orphan) diseases which have been associated to impaired epithelial repair in the gastro-intestinal track for which there are very limited treatment options: Sjoergen Syndrome (SjS) and - Eosinophilic Esophagitis (EoE). The plan of activities involves the following steps: 1) Biological efficacy testing of the-1 and the-2 in a zebrafish Tight Junction model and in mouse models of the diseases under focus; 2) Development of IPR based on - the biological testing; 3) Consolidate outcomes of steps 1 and 2 into a business plan; 4) Present the business plan to VC funds to seek for extra round of funding. The long-term aim is clinical development of our candidates not only in the context of - SjS and EoE but also towards a range of o diseases where impaired epithelial barrier function is impaired and a cause of morbidity. - - 2018-03-31, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2015 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Portugal - - - EMODI - - - ERC-2015-PoC - - - 713735 - - - - - FACULDADE DE CIENCIAS MEDICAS DA UNIVERSIDADE NOVA DE LISBOA - UNIVERSIDADE NOVA DE LISBOA - - - EUR 160 635,60 - - - A genetic model for neurorehabilitation - - - EUR 160 635,60 - - - Portugal - Portugal - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Coordinated walking in vertebrates and multi-legged invertebrates such as the fruit fly Drosophila melanogaster is controlled by an evolutionarily conserved network capable to control movement in a fast, stable, and - energy-efficient way. At the same time, it provides the flexibility to adapt to changes in the terrain, load, and internal motor representations due to disease or injury. Currently, the contribution of different brain structures responsible for the - recovery process is only partially understood and, importantly, the role of specific genes remains mostly elusive. Preliminary data shows that adult Drosophila flies in which the two middle legs were amputated improve their gait performance gradually - over the course of a few days engaging in a more controlled gait. We also find that mutants for the learning and memory gene rutabaga lack any kind of short- or long-term recovery. These results suggest that flies can readjust their motor circuitry - upon injury and that a mechanism of synaptic plasticity might be involved. - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Portugal - - - GEMiNI - - - H2020-MSCA-IF-2016 - - - 752891 - - - - - UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA - - - EUR 170 121,60 - - - Central Authority and Local Strenght in Early Middle Ages: Comparing social complexity in Northern Iberia and Central Italy (8th – 10th centuries) - - - EUR 170 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - Intending the Early Middle Ages as one of the most astonishing political and social laboratories in Europe’s history, the main goal of “CALOSEMA” project is the study of social complexity between the 8th and 10th centuries, - comparing societies and political landscapes from two European macro-regions: Northern Iberia and Central Italy, in order to (a) to investigate social, economic and political complexities on a continental scale, with the main intention of - interpreting “landscapes of social and political inequality” going beyond the contraposition between History and Archaeology; (b) to create a social theory which would allow the insertion of medieval examples in the existing historiographical debates - and, finally, (c) to deepen the concepts social and political inequality in the historical evolution of societies and powers which must be always considered as processes in progress, (d) to deconstruct historiographical rhetorics about the birth of - different nations and states in Europe (and the origin of Europe itself) in the Early Middle Ages. - - 2019-09-24, ongoing project - - - 2017-09-25 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - CALOSEMA - - - H2020-MSCA-IF-2016 - - - 748161 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 183 454,80 - - - Elucidating novel post-transcriptional regulatory mechanisms in neural development - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - During brain development, neural stem cells (neuroblasts) divide asymmetrically to produce a neuroblast and a neural progenitor cell, the ganglion mother cell (GMC), which will later divide to produce two neurons or glia. - Asymmetric protein localization and transcriptional activation are two well-established mechanisms that influence cell fate decisions during this process. I hypothesize that a relatively unexplored regulatory component—mRNA stability—also plays a - major role in neural differentiation. mRNA stability is regulated to achieve high temporal and spatial control of gene expression and may therefore provide a powerful way to establish or reinforce cell fate decisions in the nervous system. However, - little is known about the functions of regulated mRNA stabilization or decay during development of the brain (or any other complex tissue). Our lab recently discovered that the mRNA encoding a key conserved neural differentiation-promoting - transcription factor, Prospero, is unstable in Drosophila neuroblasts, but is stabilized in the more differentiated GMCs. This proposal seeks to expand upon this finding and to determine the extent of mRNA stability regulation and its functional - significance in the developing brain. I aim to develop a novel genome-wide technique that will allow quantitative comparison of mRNA decay rates between neuroblasts and GMCs. I will then use this technique to query the function of conserved - RNA-binding proteins in the regulation of neural mRNA stability. Finally, I will use our state-of-the-art live brain imaging assays to determine the functional requirement for specific regulatory events in brain development at the cellular and - molecular levels. The experiments described in this proposal have the potential to uncover a major new class of post-transcriptional regulatory events that determine the balance between proliferation and differentiation in the developing brain. - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - Brain_stability - - - H2020-MSCA-IF-2016 - - - 750928 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 195 454,80 - - - Learning under Conflict: Effects of political violence on the educational attainment of Palestinian students in the West Bank - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - This project aims to examine the causal effect of the Israeli-Palestinian conflict on the achievements of Palestinian high school students in their final exams that conclude the high school degree between the years 1998-2012, - and the mechanism behind it. The analysis in the project will rely on a unique data source, which will ensure a relatively clean identification of the effects of conflict on Palestinian students' achievements. Data on students' achievements and - schools include unique data on the individual test scores in all subjects at the Palestinian high school final exam (the Tawjihi General Examination) for the whole population of Palestinian students enrolled in their final year of the Arts and the - Scientific curricula, and information on the characteristics of all high schools in the West Bank, including unique data on the teachers. The custom-made data on political violence will be comprised of datasets stemming from different sources. The - first source is Geographic Information System (GIS) data on various types of conflict-induced restrictions to mobility, including check-points, and roadblocks, within the West Bank, which enable a calculation of the gap of distance and time between - individual’s locality of residence and locality of school, with and without the presence of Israeli physical barriers to movement. The second source is conflict-related Palestinian fatalities and prisoners. - - - 2019-07-04, ongoing project - - - 2017-07-05 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - CSPIWB - - - H2020-MSCA-IF-2016 - - - 752410 - - - - - DEUTSCHES ZENTRUM FUR NEURODEGENERATIVE ERKRANKUNGEN EV - - - EUR 239 860,80 - - - Assessment of Reserve: Translational Evaluation of Medical Images and Statistics-Prediction models for outcomes of brain health - - - EUR 239 860,80 - - - Germany - - - Research Organisations - - Stroke and cognitive decline are among the leading contributors to disease burden and long-term disability worldwide. Despite their prevalence, the contributing disease processes are not fully understood. This is in part due - to the lack of (early) prediction models and ways to characterize protective mechanisms, which can help to distinguish between patients and healthy individuals before symptoms manifest. Such prediction models can facilitate prevention strategies for - adverse cognitive and functional outcomes, thereby enriching patients’ life quality and reduce the economic burden on society. Advanced neuroimaging techniques, such as MRI, have provided additional insight into the underlying disease biology. One - major challenge when using neuroimaging techniques lies in the fact that large amounts of data are required to account for variations in clinical presentation and assessment, necessitating the use of dedicated pipelines for extracting phenotypes. - However, most pipelines are developed in research settings and tend to fail when applied to real-life clinical cohorts, leading to a subpar use of rich, available patient datasets. - - 2020-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Germany - - - ARTEMIS - - - H2020-MSCA-IF-2016 - - - 753896 - - - - - UNIVERSITY OF KEELE - - - EUR 251 857,80 - - - Motivation–cognition interaction in healthy ageing and Parkinson’s disease - - - EUR 251 857,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Europe is greying. This has enormous economic and social costs for the entire society, through greater numbers of healthy older adults with cognitive decline, and of people with neurodegenerative disorders that can lead to - dementia, such as Parkinson’s disease (PD). MOTIVAGEING aims to address this issue by proposing a new approach for the enhancement of working memory (WM) capacity, in order to improve cognitive function, quality of life and wellbeing of healthy older - adults and PD patients. In fact, there is no current effective treatment for age-related WM decline or WM deficits and related behavioural and affective problems in PD patients. Based on a promising new theory of cognitive neuroscience, the - Motivation-Cognition Interaction (MoCoInt) framework, the present plan employs an interdisciplinary approach: in Study 1, an innovative multimodal functional neuroimaging method is proposed to analyse for the first time the neural mechanisms of - MoCoInt in healthy ageing. The new evidence will provide a foundation for Study 2, in which the efficacy of a novel WM training procedure, based on MoCoInt, will be tested in healthy older adults in order to improve their WM capacity. Finally, to - understand if this new training procedure can be employed to treat WM deficits in PD, Study 3 investigates for the first time MoCoInt mechanisms in PD patients in relation to pharmacological treatment, through the conduct of a randomised controlled - drug trial. Results will enable to extend MoCoInt to healthy and pathological ageing, and to develop a new framework that will be available as a new theoretical model for both researchers and clinicians. MOTIVAGEING will therefore have both a - significant scientific multidisciplinary impact, filling several gaps in knowledge in cognitive neuroscience, cognitive and clinical neuropsychology, and a valuable social and economic impact in the European Union, helping to address the crucial - issues posed by the ageing population. - - 2021-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - Motivageing - - - H2020-MSCA-IF-2016 - - - 749084 - - - - - UNIVERSITY OF LEEDS - ACADEMISCH ZIEKENHUIS LEIDEN - KING'S COLLEGE LONDON - FACULTY OF SCIENCE UNIVERSITY OF ZAGREB - THE UNIVERSITY OF EDINBURGH - GLYXERA GMBH - GENOS DOO ZA VJESTACENJE I ANALIZU - ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA - - - EUR 2 864 761,20 - - - Innovative training in methods for future data - - - EUR 2 864 761,20 - - - United Kingdom - Netherlands - United Kingdom - Croatia - United Kingdom - Germany - Croatia - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - IMforFUTURE is an innovative multidisciplinary and intersectoral research training programme which addresses current shortcomings in omics research. We aim to open the new research horizon in integration of genetics, - glycomics, and epigenomics datasets into systems biology by developing innovative methods for high throughput omics and for integrative analysis of omics data. We focus on ageing, which is the biggest single risk factor for many diseases. By - application of our novel methods to emerging datasets representing inflammation and immunology, IMforFUTURE will contribute to understanding of the underlying biological processes involved in diseases and ageing. - - 2021-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - IMforFUTURE - - - H2020-MSCA-ITN-2016 - - - 721815 - - - - - UNIVERSITEIT LEIDEN - - - EUR 197 725,50 - - - Women at the Cutting Edge. Assessing the gendered impact of industrial logging on well-being in Solomon Islands. - - - EUR 197 725,50 - - - Netherlands - - - Higher or Secondary Education Establishments - - Women are often negatively affected by industrial logging in tropical forests. They are excluded from decision-making, and are vulnerable to the sexual exploitation, alcoholism and conflict associated with this extractive - industry. However, the scientific literature on the impacts of logging on women’s well-being is fragmented, and the subject receives little attention from policy and industry. This project aims to address this gap by: 1) publishing 3 peer-reviewed - articles in high-impact, open-access journals on the gendered impacts of logging in Solomon Islands, based on an innovative combination of ethnographic and quantitative research methods; 2) compiling case studies on women in logging concessions in a - special issue of the journal of the European Tropical Forest Research Network; 3) developing a methodological toolkit for the systematic assessment of women’s well-being in forest concessions. The project results will be further communicated to - professional and lay-audiences through oral presentations, policy briefs, newsletters, a website and on-line articles. - - 2019-11-30, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Netherlands - - - WACE - - - H2020-MSCA-IF-2016 - - - 748242 - - - - - UNIWERSYTET ROLNICZY IM. HUGONA KOLLATAJA W KRAKOWIE - KOBENHAVNS UNIVERSITET - THE UNIVERSITY OF NOTTINGHAM - UNIVERSITEIT GENT - TECHNISCHE UNIVERSITAET BERLIN - KATHOLIEKE UNIVERSITEIT LEUVEN - - - EUR 2 078 485,56 - - - Food science, technology and engineering - European Joint Doctorate training towardsknowledge, skills and mobility - - - EUR 2 078 485,56 - - - Poland - Denmark - United Kingdom - Belgium - Germany - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The objective of the proposal is to train 8 early stage researches (ESR) in an innovative, international PhD program, to become top-class specialists and professional leaders, highly demanded in the job market, ready to - introduce innovations and manage advanced research. The completion of the training programme will provide ESRs with appropriate knowledge, skills and awareness of the science-business reality, crucial for scientific and/or commercial based research - projects. - - 2020-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-EJD - European Joint Doctorates - - - Poland - - - EJDFoodSci - - - H2020-MSCA-ITN-2016 - - - 722166 - - - - - UNIVERSIDAD POMPEU FABRA - - - EUR 170 121,60 - - - The Role of the Ethnic Majority in Integration Processes: Attitudes and Practices towards Immigrants in Catalan Institutions - - - EUR 170 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - This project proposal aims to take research on diversity management and integration further by focusing on how ethnic diversity is represented in three central Catalan institutions: the public school system, the Catalan police - force and the City council of Barcelona. The case of Catalonia appears particularly relevant for an empirical study on the actual representation of diversity given its pronounced intercultural policy focus, while socio-economic inequality between - natives and immigrants is vast, and many immigrants live in situations of precariousness and marginalization. - - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - REPCAT - - - H2020-MSCA-IF-2016 - - - 747075 - - - - - UNIVERSITEIT ANTWERPEN - - - EUR 160 800 - - - Anticancer activity of plasma activated medium and its underlying mechanisms: Combined experimental and computational study - - - EUR 160 800 - - - Belgium - - - Higher or Secondary Education Establishments - - Cold atmospheric plasma (CAP) is gaining increasing interest for cancer treatment, although the application is still in its early stages. Besides direct CAP treatment of cancer cells, plasma can also be used to activate a - liquid medium, which seems to have similar anti-cancer effects as the plasma itself. This so-called plasma activated medium (PAM) is very promising for cancer treatment, as it can be more generally used, e.g., it might be directly injected into - tissue of patients. However, the anticancer potential of PAM is not yet fully understood. This is exactly the focus of this project. We will measure the reactive oxygen and nitrogen species (RONS) concentrations in PAM, and also calculate them with a - model for plasma-liquid interaction. In addition, we will study the effect of PAM on a catalase model protein by experiments, and perform atomic scale simulations for the interaction of RONS with this protein, to better understand the effect of PAM - on cancer cells, because catalase aids cancer cells in overcoming oxidative stress created by PAM. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Belgium - - - Anticancer-PAM - - - H2020-MSCA-IF-2016 - - - 743546 - - - - - THE UNIVERSITY OF NOTTINGHAM - INSTITUT FRANCAIS DES SCIENCES ET TECHNOLOGIES DES TRANSPORTS, DE L'AMENAGEMENT ET DES RESEAUX - UNIVERSITA DEGLI STUDI DI PALERMO - UNIVERSIDAD DE GRANADA - POLITECNICO DI MILANO - EIFFAGE INFRASTRUCTURES GESTION ET DEVELOPPEMENT - AECOM INFRASTRUCTURE & ENVIRONMENT UK LIMITED - GAVIN AND DOHERTY GEOSOLUTIONS LTD - DYNATEST INTERNATIONAL AS - - - EUR 3 990 940,92 - - - European Training Network on Sustainable Multi-functional Automated Resilient Transport Infrastructures. - - - EUR 3 990 940,92 - - - United Kingdom - France - Italy - Spain - Italy - France - United Kingdom - Ireland - Denmark - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Sustainable Multi-functional Automated Resilient Transport Infrastructures ETN, will bring together a stimulating platform where the stakeholders of the transport infrastructure sector will work alongside world-wide experts in - smartening of systems (developers of high-tech sensors, advanced monitoring equipment, automated structures, etc.,) with direct support from the roads, railways and airports managers. This environment will enable talented graduates to conceive the - transport infrastructure network of the future and will provide them with world-wide extended training in each of the four pillars supporting the SMARTI vision: designed to last by maximising recycling and minimizing impact (Sustainable), conceived - not for transport purposes only and towards optimisation of land use (Multi-functional), equipped for communicating with managers and users, to allow a more intuitive use and a simplified management (Automated), built to be adaptable to natural and - anthropogenic hazards (Resilient). The consortium will combine and share expertise to offer advanced scientific training structured into network-wide thematic taught modules combined with original research supported by secondments that will expose - fellows to both academia and industry and will also allow them with the possibility to be award with Doctoratus Europeus. The training programme will be enriched by specific modules to support job creation by enabling the fellows with business, - entrepreneurship, communication, project management and other transferrable skills. A tailored Dissemination strategy will evaluate the variety of channels and means appropriate to allow the fellows to be prepared and successful in reaching both - scientific and larger public audiences. As a result, SMARTI ETN will create a new generation of highly-skilled and appealing professionals that will be in great demand in this rapidly expanding field and will benefit Europe and developing countries. - - 2021-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - SMARTI ETN - - - H2020-MSCA-ITN-2016 - - - 721493 - - - - - TECHNISCHE UNIVERSITAET MUENCHEN - - - EUR 159 460,80 - - - Direct Pathway Cloning of Neglected Bacteria in the Hunt for Novel (Bio-)Chemistry - - - EUR 159 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - To overcome recent global health threats, such as antibiotic resistance, a resurgence in the discovery of new chemical and thus biomedical diversity from microbial sources is needed. Genome mining in combination with - heterologous expression is an approach that will overcome these challenges. It involves incorporation of yet uncharacterized natural product genetic loci into a fast growing heterologous host. For this approach, a prolific source of novel natural - product gene clusters is vital. Our collaboration with the Zentralinstitut für Ernährungs- und Lebensmittelforschung (ZIEL, Technische Universität München) provides direct access to bacterial isolates completely unexplored in regards to their - potential for natural product biosynthesis. Our genome analyses have revealed that many of the ZIEL isolates harbor a large number of uncharacterized natural product gene clusters. Thus, the aim of this proposal is to heterologously express natural - product gene clusters from these neglected bacteria to discover novel natural product (bio-)chemistry. Because these organisms are poorly studied, the likelihood of discovering rare or novel biochemistry is immensely increased. Here, we will utilise - a novel combination of synthetic biology techniques referred to as Direct Pathway Cloning. This will enable expression vectors to be constructed by large-amplicon PCR (up to 20kb) coupled to Gibson assembly. Development of the methodology is set to - revolutionise synthetic biology and metabolic engineering. Downstream outcomes of this proposal will be the identification of novel, potentially bioactive natural products, the characterisation of unusual biochemistry and the addition of enzymes to - the ‘biocatalytic toolkit’ for natural product synthesis and structural alteration. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - DiPaC_MC - - - H2020-MSCA-IF-2016 - - - 745435 - - - - - TECHNISCHE UNIVERSITAET WIEN - TECHNISCHE UNIVERSITAET WIEN - - - EUR 1 513 335,34 - - - X-ray-waveforms at the Space-Time Resolution Extreme for Atomic-scale Movies - - - EUR 1 513 335,34 - - - Austria - Austria - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Nonlinear optics revolutionized the ability to create directed, coherent beams particularly in spectral regions where lasers based on conventional population inversion are not practical. New breakthroughs in extreme nonlinear - optics promise a similar revolution in the X-ray regime. In a dramatic and unanticipated breakthrough, an international team lead by the PI demonstrated that the high harmonic generation process (HHG) driven by mid-IR lasers can be used to generate - keV photons, implementing a >5000 order nonlinear process, while still maintaining the full phase matching that is necessary for good conversion efficiency. This work represents the most extreme, fully coherent upconversion for electromagnetic - waves in the 50 year history of nonlinear optics. Moreover, the limits of HHG are still not understood, either theoretically or experimentally. It may be possible to generate coherent hard X-rays using a tabletop-scale apparatus. - - 2022-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Austria - - - XSTREAM - - - ERC-2016-STG - - - 716950 - - - - - STICHTING VU - STICHTING VU - - - EUR 2 499 714 - - - Becoming A Minority - - - EUR 2 499 714 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In the last forty years, researchers in the Field of Migration and Ethnic Studies looked at the integration of migrants and their descendants. Concepts, methodological tools and theoretical frameworks have been developed to - measure and predict integration outcomes both across different ethnic groups and in comparison with people of native descent. But are we also looking into the actual integration of the receiving group of native ‘white’ descent in city contexts where - they have become a numerical minority themselves? In cities like Amsterdam, now only one in three youngsters under age fifteen is of native descent. This situation, referred to as a majority-minority context, is a new phenomenon in Western Europe and - it presents itself as one of the most important societal and psychological transformations of our time. I argue that the field of migration and ethnic studies is stagnating because of the one-sided focus on migrants and their children. This is even - more urgent given the increased ant-immigrant vote. These pressing scientific and societal reasons pushed me to develop the project BAM (Becoming A Minority). The project will be executed in three harbor cities, Rotterdam, Antwerp and Malmö, and - three service sector cities, Amsterdam, Frankfurt and Vienna. BAM consists of 5 subprojects: (1) A meta-analysis of secondary data on people of native ‘white’ descent in the six research sites; (2) A newly developed survey for the target group; (3) - An analysis of critical circumstances of encounter that trigger either positive or rather negative responses to increased ethnic diversity (4) Experimental diversity labs to test under which circumstances people will change their attitudes or their - actions towards increased ethnic diversity; (5) The formulation of a new theory of integration that includes the changed position of the group of native ‘white’ descent as an important actor. - - 2022-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Netherlands - - - BAM - - - ERC-2016-ADG - - - 741532 - - - - - OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN - OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN - - - EUR 2 496 525 - - - Simulating 2d Spin Lattices with Ion Crystals - - - EUR 2 496 525 - - - Austria - Austria - - - Research Organisations - Research Organisations - - The objective of this project is to experimentally realize a 100-particle quantum simulator with complete quantum control at the single-particle level that will be used for investigating models of interacting spins in two dimensions. - - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Austria - - - SPICY - - - ERC-2016-ADG - - - 741541 - - - - - LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE - LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE - - - EUR 1 499 094 - - - Investigating the predictors of intimate partner violence: a mixed method longitudinal study in Tanzania - - - EUR 1 499 094 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This study proposes a major advance in research on intimate partner violence (IPV), a prominent public health and human rights issue. Worldwide, it is estimated that one in three women experience physical and/or sexual - violence by a partner in their lifetime, with even higher rates reported in sub-Saharan Africa (WHO 2013). Cross-sectional surveys have documented the adverse health impacts of IPV and the factors that increase risk of female victimisation and male - perpetration. Nonetheless, theoretical and programmatic development has stalled due to lack of clarity on the temporality of identified associations: do documented associations represent risk factors for violence or do they reflect the consequences - of abuse? This deficit of understanding is especially pressing in low and middle income countries (LMICs) where few longitudinal cohort studies with IPV as an outcome exist. This study seeks to address this gap by following forward in time a cohort - of 1200 Tanzanian women, using state of the art methods to measure violence, encourage disclosure and ensure participant safety. Both quantitative and qualitative data will be collected at 4 discrete time points over 5 years, making this the largest - longitudinal study of IPV ever undertaken in the developing world. In addition, an in-depth study of 40 men and a cross-sectional survey of 600 men will be conducted. The goal of the research is to advance our understanding of the predictors and - consequences of IPV to better inform the design of interventions to reduce violence in LMICs. Specifically the study aims to: 1) advance the theoretical frameworks of intimate partner violence; 2) investigate the temporality of key factors linked to - IPV; 3) map the dynamics of partner violence over time; 4) and investigate pathways leading to intimate partner violence. This research is of immediate necessity to address a vital public health challenge of our time and has the strong potential to - have a long lasting impact on shaping the research agenda on intimate partner violence. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - IPV_Tanzania - - - ERC-2016-STG - - - 716458 - - - - - UNIVERSITEIT LEIDEN - UNIVERSITEIT LEIDEN - - - EUR 2 498 296 - - - Open Philology: The Composition of Buddhist Scriptures - - - EUR 2 498 296 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Buddhist sūtras are fundamental sources for understanding the beliefs that once dominated, and largely continue to dominate, Asian societies. But classical philological approaches to these texts, assuming an Ur-text and linear - development, misrepresent their nature and obscure their history. Like oral literature the sūtras are authorless and textually fluid, their content formulaic and modular, and the situation complicated by their huge volume and the linguistic diversity - of their extant versions. Their fluidity and the absence of an Ur-text makes traditional stemmatic editing inappropriate. Other options are also unacceptable: eclectic editions conflate distinct sources, creating texts which never existed - historically, while exclusive focus on a single version ignores the tradition’s true richness. - - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Netherlands - - - OpenPhilology - - - ERC-2016-ADG - - - 741884 - - - - - ECOLE NORMALE SUPERIEURE DE LYON - ECOLE NORMALE SUPERIEURE DE LYON - FONDATION POUR L'UNIVERSITE DE LYON - - - EUR 2 496 242,50 - - - Silver Isotopes and the Rise of Money - - - EUR 2 496 242,50 - - - France - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - - Silver was the primary metal of economic exchange and military finances in ancient Mediterranean and Near-Eastern societies. Silver isotopes will help quantify monetization of these societies by identifying Ag mineral sources, - monetary sinks, and its major transfer routes. High-precision stable Ag isotope analysis initiated in Lyon has shed new light on the provenance of silver coinage. This is because Ag isotopes are distinctive of coinage’s intrinsic value in contrast to - traditionally-used Pb and Cu isotopes, which may characterize impurities or additives. - - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - France - - - SILVER - - - ERC-2016-ADG - - - 741454 - - - - - UNIVERSITEIT LEIDEN - UNIVERSITEIT LEIDEN - UNIVERSITE DE LIEGE - - - EUR 2 500 000 - - - Rural Riches. The bottom-up development of Post-Roman Northwestern Europe (450-640) - - - EUR 2 500 000 - - - Netherlands - Netherlands - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The question as to how Europe emerged from the collapse of the Roman state in the West has been the subject of academic debate for over a century. Most modern authors agree on the idea that the post-Roman economic development - was the result of the initiatives and the demand of the elite. This paradigm of elite control of production and (long-distance) trade seems to be at odds with the vast amounts of objects, often precious and of exotic origin, that are found in the - thousands of richly furnished cemeteries of even the smallest rural communities. - - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Netherlands - - - Rural Riches - - - ERC-2016-ADG - - - 741340 - - - - - UNIVERSITAET LEIPZIG - UNIVERSITAET LEIPZIG - - - EUR 1 860 875 - - - Differential Inclusions and Fluid Mechanics - - - EUR 1 860 875 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Important problems in science often involve structures on several distinct length scales. Two typical examples are fine phase mixtures in solid-solid phase transitions and the complex mixing patterns in turbulent or multiphase - flows. The microstructures in such situations influence in a crucial way the macroscopic behavior of the system, and understanding the formation, interaction and overall effect of these structures is a great scientific challenge. Although there is a - large variety of models and descriptions for such phenomena, a recurring issue in the mathematical analysis is that one has to deal with very complex and highly non-smooth structures in solutions of the associated partial differential equations. - - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - DIFFINCL - - - ERC-2016-COG - - - 724298 - - - - - EUROPEAN MULTIDISCIPLINARY SEAFLOORAND WATER COLUMN OBSERVATORY - EUROPEAN RESEARCH INFRASTRUCTURE CONSORTIUM (EMSO ERIC) - ISTITUTO NAZIONALE DI GEOFISICA E VULCANOLOGIA - INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - NATURAL ENVIRONMENT RESEARCH COUNCIL - HELLENIC CENTRE FOR MARINE RESEARCH - INNOVA SRL - MARINE INSTITUTE - UNIVERSITAT POLITECNICA DE CATALUNYA - INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU GEOLOGIE SI GEOECOLOGIE MARINA-GEOECOMAR - INSTITUTO PORTUGUES DO MAR E DA ATMOSFERA IP - - - EUR 4 359 451,25 - - - Implementation of the Strategy to Ensure the EMSO ERIC’s Long-term Sustainability - - - EUR 4 370 279,41 - - - Italy - Italy - France - France - United Kingdom - Greece - Italy - Ireland - Spain - Romania - Portugal - - - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - - EMSO-Link is a 3-year project underpinning the long-term sustainability of EMSO ERIC, the pan-European distributed Research Infrastructure (RI) composed of fixed point open ocean observatories for the study and monitoring of - European seas. EMSO pursues the long-term objective to be part of the upcoming European Ocean Observing System (EOOS), which is expected to integrate multiple platforms and data systems, including other ERICs, to achieve the first sustained, - standardized and permanent observatory network of the European seas. EMSO ERIC coordinates the access to the facilities and supports the management of data streams from EMSO observatories. - - - 2020-02-29, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-03-2016-2017 - Individual support to ESFRI and other world-class research infrastructures - - - CSA - Coordination and support action - - - Italy - - - EMSO-Link - - - H2020-INFRADEV-2016-1 - - - 731036 - - - - - UNIVERSITAET SIEGEN - - - EUR 159 460,80 - - - Development of photoswitchable ligands for the reversible and selective assembly with RNA - - - EUR 159 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - The proposed project aims at the development of novel functional ligands whose association with ribonucleic acid (RNA) is reversibly activated by light. As several RNA forms are essential key elements in physiological - processes, the control of their function or malfunction by the reversible binding of photoswitchable ligands possesses a great potential as a tool in anticancer, antiviral and antimicrobial therapy. Surprisingly, this innovative approach towards a - controlled reversible generation of RNA binders was mainly neglected in this highly topical research field. Hence, in this project photochromic hemi-indigo and fulgide derivatives are chosen as a platform for the design of photo-responsive RNA - ligands, because i) they exhibit general features of RNA binders; ii) their structure can be reversibly modified by light, iii) the core structures are readily synthesized, and iii) the substitution pattern can be easily varied to enable fine-tuning - of binding selectivity based on structure-activity relationships. In addition, conjugates that comprise two photoactive RNA-binding units will be obtained and studied because such bifunctional binders are expected to have very high affinity and - selectivity toward RNA. An extensive library of derivatives will be synthesized and tested for their photocontrollable association with RNA. As a special method, real-time NMR-spectroscopic studies with direct irradiation of the sample inside a - specifically designed spectrometer will be used to assess in detail the dynamics in the course of the photoinduced ligand–RNA interactions. Overall, it is anticipated that this systematic approach will enable the identification and development of - lead structures for controllable RNA-targeting drugs with a great pharmacological potential. Moreover, the high interdisciplinary, innovative character of this challenging project gives the researcher an excellent opportunity to achieve professional - maturity and open up best career possibilities. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - PHOTORNA - - - H2020-MSCA-IF-2016 - - - 749788 - - - - - UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA - IMG PHARMA BIOTECH SOCIEDAD LIMITADA - NANOVEX BIOTECHNOLOGIES SL - UNIVERSIDAD COMPLUTENSE DE MADRID - INESC MICROSISTEMAS E NANOTECNOLGIAS-INSTITUTO DE ENGENHARIA DE SISTEMAS DE COMPUTADORES PARA OS MICROSISTEMAS E AS NANOTECNOLOGIAS - UNIVERSIDADE DO PORTO - VIENNA BIOCENTER CORE FACILITES GMBH - ICETA INSTITUTO DE CIENCIAS, TECNOLOGIAS E AGROAMBIENTE DA UNIVERSIDADE DO PORTO - - - EUR 846 000 - - - Novel magnetic nanostructures for medical applications - - - EUR 846 000 - - - Spain - Spain - Spain - Spain - Portugal - Portugal - Austria - Portugal - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - - MAGNAMED designs, fabricates, and assesses novel magnetic nanostructures (MNS) with unique spin configurations for innovative diagnostics and therapy techniques. An early stage detection and an effective treatment are - keystones to reduce cancer mortality. Current clinical procedures fail to detect small concentration of tumoral biomarkers. Magnetic nanoparticles (MNP), like beads, have attracted much attention for their capability to improve cancer detection - limits and treatment technologies. However, there are several limitations to the use of MNP. As an emerging alternative, MNS are being explored. Unlike MNP, MNS (e.g. nanodisks) present a planar shape with novel properties for diagnosis: high - magnetic moment and large size, which can significantly improve the sensor sensitivity, and for therapy: due to their planar shape, alternate magnetic fields provoke a magneto-mechanical action on the cell membrane that triggers cell death. The - efficiency of MNS in these two medical applications has not been investigated yet for MNS at the nanometer scale. The challenge of this project is to produce MNS with nanometer dimensions suitable for medical applications. Several lithography - techniques will be used to fabricate MNS in vortex and antiferromagnetic spin configurations covering a broad size range (40 to 4000 nm). After functionalization, MNS will be exploited in: (i) Diagnostics, using giant magnetoresistance (GMR) sensors - for the detection of tumoral biomarkers (dermcidin and carcinoembryonic antigen), and (ii) Therapy, effectiveness of tumoral cell annihilation by the magneto-mechanical action of MNS will be evaluated in vitro assays of melanoma and colorectal cancer - cells. MAGNAMED is a cross-sectoral and interdisciplinary project involving Physics, Chemistry and Medicine. Findings will have a medium-term impact on the European strategy for early stage detection of cancer and a long-term impact on the - development of novel and groundbreaking therapeutics techniques. - - 2021-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Spain - - - MAGNAMED - - - H2020-MSCA-RISE-2016 - - - 734801 - - - - - SZKOLA GLOWNA GOSPODARSTWA WIEJSKIEGO - SZKOLA GLOWNA GOSPODARSTWA WIEJSKIEGO - - - EUR 1 413 750 - - - Entrapment of Hypoxic Cancer by Macrophages Loaded with HAP - - - EUR 1 413 750 - - - Poland - Poland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The proposed project seeks to open a new research front within the field of drug delivery to the solid tumours. Unsatisfactory response of tumours to chemotherapy is mainly related to impaired diffusion of the anticancer drug - because of decreased drug uptake due to poor vasculature. Moreover, the drug is not able to penetrate the most hypoxic sites. Cells from these ‘untreated’ sites are responsible for relapse and metastasis. However, these avascular regions attract - macrophages that migrate even to areas far away from blood vessels. Therefore, they might constitute a unique delivery system of drug containing particles to these parts of the tumour mass. A promising example of such particles that could be used are - ferritins, whose caged architecture allows for efficient drug encapsulation and whose uptake from macrophage cells has been well demonstrated. My recent ground breaking finding was that macrophages are also able to specifically and actively transfer - these taken up ferritins (loaded with the compound of choice) to cancer cells. Thus, these preliminary results indicate the possibility to use macrophages to deliver ferritin encapsulated compounds directly to the tumour cells even in its hypoxic - areas. Then, the use of hypoxia-activated prodrugs (HAP) which are selectively activated only in hypoxic regions will be exploited in order to make cancer therapy safer. However, the molecular mechanism of ferritin uptake by macrophages, their - storage, and transport to the cancer cells represent key issues to be investigated and pave the way to the experimental design of the present project. - - - 2021-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Poland - - - McHAP - - - ERC-2016-STG - - - 715048 - - - - - AKADEMIA SZTUKI W SZCZECINIE - UNIVERZITA JANA EVANGELISTY PURKYNE V USTI NAD LABEM - STOWARZYSZENIE EDUKACJA, NAUKA, KULTURA - UNIVERSITA DEGLI STUDI DI MACERATA - POLISH UNIVERSITY ABROAD - - - EUR 630 000 - - - Technologies of Imaging in Communication, Art, and Social Sciences - - - EUR 630 000 - - - Poland - Czech Republic - Poland - Italy - United Kingdom - - - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Other - Higher or Secondary Education Establishments - Research Organisations - - In the face of images’ proliferation in all areas of human life, we can talk about the necessity of education on how to adjust to and operate in visual space, to read even and develop the language reflecting such culture. - - - 2021-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Poland - - - TICASS - - - H2020-MSCA-RISE-2016 - - - 734602 - - - - - HERIOT-WATT UNIVERSITY - THALES ALENIA SPACE FRANCE - LARGE SPACE STRUCTURES GMBH - AURORA SOFTWARE AND TESTING S.L. - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - FUNDACION PRODINTEC - - - EUR 1 834 895,07 - - - Radio Technologies for Broadband Connectivity in a Rapidly Evolving Space Ecosystem: Innovating Agility, Throughput, Power, Size and Cost - - - EUR 1 834 895,07 - - - United Kingdom - France - Germany - Spain - France - Spain - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - - Radio signals are core to space systems and services; they are the backbone of satellite broadcasting & communications and further represent the primary underpinning technology of the nearly ubiquitous space-based radio - navigation services as well as a large number of Earth observation instruments. Radio technologies are therefore central in defining the investment return for a wide range of missions and reflect to a significant fraction of the combined space and - ground segment infrastructure. As the frightening rates of concurrent advances in space-related services, business models and technologies are driving the space ecosystem to a new age, the need to re-invent radio technologies for space is becoming - increasingly urgent; while the sector is proactively looking for the next game changer, a whole new class of emerging and forecasted missions place urgent demands for drastic reduction in cost with a concurrent radical improvement in throughput, - agility, volume/mass and power consumption. - - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-EID - European Industrial Doctorates - - - United Kingdom - - - REVOLVE - - - H2020-MSCA-ITN-2016 - - - 722840 - - - - - UNIVERSITY OF SOUTHAMPTON - - - EUR 195 454,80 - - - Black Holes in String Theory and Holography - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Black holes are among the most fascinating and enigmatic objects in our universe. The internal structure of black holes is of significant interest for quantum gravity, for astrophysical phenomena, and for the study of quantum - entanglement in systems with many degrees of freedom. - - - 2019-09-30, Grant Agreement terminated - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - BH-STRING-HOLO - - - H2020-MSCA-IF-2016 - - - 747665 - - - - - UNIVERSITAET HAMBURG - UNIVERSITY OF YORK - ERASMUS UNIVERSITEIT ROTTERDAM - FACULDADE DE ECONOMIA DA UNIVERSIDADE NOVA DE LISBOA - UNIVERSIDADE NOVA DE LISBOA - UNIVERSITA COMMERCIALE LUIGI BOCCONI - SYDDANSK UNIVERSITET - ST JUDE MEDICAL COORDINATION CENTER - - - EUR 3 877 749,36 - - - Improving Quality of Care in Europe - - - EUR 3 877 749,36 - - - Germany - United Kingdom - Netherlands - Portugal - Portugal - Italy - Denmark - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Improving quality of care has been given too little attention in health economic research in the past although it is the central goal of health care systems in Europe. The proposed ETN on “Improving Quality of Care in Europe - (IQCE)” aims to address this gap and has the following aims: 1) Create new evidence and improve existing health economic research in the field of quality of care. Research gaps are addressed by empirical, theoretical and experimental approaches with - a focus on innovative econometric methods using novel access to databases. 2) Establish a close link of the topical PhD projects to health policy and practice ensuring high relevance and practical applicability of results. Implementation of project - results can potentially enhance performance of European health care systems. 3) Train PhD fellows to be experts in the field of quality of care and obtain excellent profiles for different career paths in health economic research or practice. 4) - contribute to better coordination of currently fragmented health economic research in Europe. This will improve the competitive position of European health economic research. 5) serve as a model for joint doctorate programmes in health economics in - Europe. This will drive the development of PhD programmes in health economics in Europe, which currently are scarce. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - IQCE - - - H2020-MSCA-ITN-2016 - - - 721402 - - - - - CIENCIA VIVA-AGENCIA NACIONAL PARA A CULTURA CIENTIFICA E TECNOLOGICA - INSTITUTO DE BIOLOGIA MOLECULAR E CELULAR-IBMC - UNIVERSIDADE NOVA DE LISBOA - INSTITUTO DE TECNOLOGIA QUIMICA E BIOLOGICA - UNIVERSIDADE NOVA DE LISBOA - UNIVERSIDADE DE COIMBRA - - - EUR 153 000 - - - Foreseeing Opportunities, Risks and Emergent Science Issues for the next Generation: Highlighting Trends - - - EUR 153 000 - - - Portugal - Portugal - Portugal - Portugal - Portugal - - - Other - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Our proposal for ERN 2016-17 is focussed on foresight, exploring alternatives to consider and manage the future with researchers and the public, envisioning new trends of science and technologies and of their impacts on - society. Of special concern are the complex problems and challenges that humanity faces: climate change, sustainable energy, food and water supply, ageing and social inclusion, to name but a few of the global trends identified for the next 10-15 - years. - - 2017-11-30, closed project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.5."> - - - MSCA-NIGHT-2016 - European Researchers' Night - - - CSA - Coordination and support action - - - Portugal - - - FORESIGHT - - - H2020-MSCA-NIGHT-2016 - - - 722968 - - - - - KOBENHAVNS UNIVERSITET - - - EUR 200 194,80 - - - An exploration into the feasibility of simultaneously achieving ‘No Net Loss’ of biodiversity and ecosystem services, in an uncertain and changing world - - - EUR 200 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - We are evidently currently witnessing an ongoing loss of global biodiversity, caused largely by anthropogenic activity, and thought to be resulting in a loss of associated ecosystem services. However, the economic development - that often leads to net loss of ecosystem services also provides benefits to humanity. An optimal balance between development and biodiversity conservation must be found. - - 2017-08-31, Grant Agreement terminated - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - NNL - - - H2020-MSCA-IF-2014 - - - 655497 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 183 454,80 - - - Decoding planetary compositions using observations and modelling of planet-forming disks - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Our sun is host to eight planets, and recent discoveries have revealed that there is at least one planet per star in the Galaxy. Moreover, small, rocky planets like the Earth outnumber the Jupiter-like gas giants. The bulk - elemental composition of most planets is not yet known, but evidence from the solar system and some extrasolar (proto-)planetary systems suggests there are considerable variations in the abundance of elements such as carbon, chlorine, iron and - others. Some of these variations are seen in the rocky planets, others apply to atmospheres of giant planets. Understanding this diversity is important, as the Earth's elemental budget is key to various aspects of its habitability. Therefore, we must - understand the origin of planetary compositions if we are to scientifically estimate the number of habitable worlds. In the DISCO project, I will study the elemental abundances in the inner and outer regions of planet-forming disks around young stars - and will build models to capture the main processes that affect the gas-ice-refractory balance of specific elements. These analytical models will be implemented in a chemically-based planet population synthesis calculation which can be compared with - known planetary compositions and will allow to predict the distribution of elemental compositions of exoplanets. - - 2019-07-02, ongoing project - - - 2017-07-03 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - DISCO - - - H2020-MSCA-IF-2016 - - - 753799 - - - - - STICHTING KATHOLIEKE UNIVERSITEIT - STICHTING KATHOLIEKE UNIVERSITEIT - - - EUR 150 000 - - - Synthetic DCs for a T cEll ProdUction Platform - - - EUR 150 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Cancer immunotherapy and adoptive transfer of genetically manipulated T cells in particular has shown promising results for the treatment of cancer. Central in cancer immunotherapy is the activation of tumour-specific T cells. - However, the wide-spread clinical use of T cell therapies remains limited due to costly, time-consuming and labour-intensive processes associated with the ex vivo activation and expansion of tumour-specific T cells. Artificial antigen presenting - cells (aAPCs) have been developed as an alternative for efficient activation of T cells. In the ERC project ‘PATHFINDER’, Prof. Figdor and his team have developed aAPCs or synthetic dendritic cells (sDCs) based on highly flexible polyisocianide (PIC) - polymers, that mimic naturally occurring DCs. The semi-flexible polymer backbone allows for proper arrangement and clustering of antigen and (co-)stimulatory markers, resulting in potent activation and expansion of T cells. With the use of PIC based - sDCs, we propose a production platform for tumour specific T cells suitable for cancer immunotherapy. In this ERC PoC project, a team of technological and commercial experts will investigate commercial feasibility of this innovative approach. - - 2019-04-30, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Netherlands - - - STEPUP - - - ERC-2016-PoC - - - 755402 - - - - - THE UNIVERSITY OF BIRMINGHAM - THE UNIVERSITY OF BIRMINGHAM - - - EUR 1 790 580 - - - A Comparative Study of Resilience in Survivors of War Rape and Sexual Violence: New Directions for Transitional Justice - - - EUR 1 790 580 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The profound trauma associated with rape and sexual violence in conflict has been extensively explored within existing scholarship. The fact that many survivors exhibit remarkable post-trauma resilience, however, remains - critically under-investigated. CSRS will address this fundamental gap by undertaking a paradigm-shifting empirical study of the underlying conditions for resilience. It will then use this data to pioneer a new, survivor-centred model of transitional - justice – the process of redressing the legacy of massive human rights abuses. - - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - CSRS - - - ERC-2016-COG - - - 724518 - - - - - KAROLINSKA INSTITUTET - - - EUR 185 857,20 - - - Skeletal Muscle Inflammation: ambivalent roles in Exercise and Diabetes - - - EUR 185 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - In Europe, 52 million people are living with diabetes, with more than 90% of them having type 2 diabetes (T2D), a multifactorial disease associated with obesity and sedentary lifestyle. It leads to severe complications such as - cardiovascular events and constitutes an unmanageable economic burden. Skeletal muscle inflammation is emerging as a potential contributor to T2D. Inflammation occurs during exercise and repair and is a hallmark of myopathies, suggesting that it - plays crucial roles in skeletal muscle homeostasis. Despite the fact that exercise is associated with inflammation, physical activity has beneficial effects on T2D, which highlights the ambivalent role of muscle inflammation in controlling glucose - homeostasis. - - 2018-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - SMILED - - - H2020-MSCA-IF-2015 - - - 704978 - - - - - KAROLINSKA INSTITUTET - - - EUR 265 059 - - - Mechanisms of cellular fatty acid homeostasis - - - EUR 265 059 - - - Sweden - - - Higher or Secondary Education Establishments - - The ability of cells to precisely maintain an internal steady state of lipids is essential for life. While homeostatic mechanisms controlling specific lipids such as sterols are well characterized, the regulation and - coordination of fatty acid (FA) and triacylglycerol (TG) synthesis remains largely unknown. Several common metabolic disorders, including obesity and type 2 diabetes, lead to nonalcoholic fatty liver disease (NAFLD), a condition characterized by - increased accumulation of hepatic TGs. Since a significant proportion of subjects with NAFLD develop potentially fatal complications, e.g. non-alcoholic steatohepatitis (NASH) and cirrhosis, it is of fundamental importance to study the mechanisms - that promote hepatic lipid accumulation. By combining advanced molecular techniques with state-of-the-art clinical research, a translational approach will be applied herein to uncover how cells coordinate glycerolipid and FA synthesis. The studies - focus on acyl-CoA:diacylglycerol O-transferase 2 (DGAT2), an enzyme catalysing the final step of TG biosynthesis and a drug target for NAFLD, which according to recent data may play an important role in FA synthesis regulation. The results generated - in this project may uncover novel mechanisms controlling cellular lipid homeostasis and provide new therapeutic avenues to treat NAFLD and NASH. - - 2020-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Sweden - - - TGDNL - - - H2020-MSCA-IF-2015 - - - 704647 - - - - - KAROLINSKA INSTITUTET - - - EUR 185 857,20 - - - Development of a high-resolution method to monitor structural changes of regulatory RNAs and therapeutic oligo-nucleotides directly in-cell. - - - EUR 185 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - MicroRNAs (miRNAs) are master regulators in cells with a complexity yet to be unraveled. By targeting one or more messenger RNAs (mRNAs) they affect a vast number of biological processes and are associated with a broad - spectrum of diseases, including cancer. This makes them potential candidates for cancer-diagnostics and -therapeutics. This opportunity can only be fully exploited by a better comprehension of how and when each mRNA is targeted by a miRNA, a fact, - which is currently still poorly understood. Besides regulatory RNAs, synthetic “anti-sense” oligonucleotides (AONs) are currently tested as cancer drugs. Progress in this field has been slow due to unspecific off-target-effects i.e. the lack of - understanding, of the mechanism of AONs targeting mRNAs. This project focuses on overcoming this lack of knowledge of the targeting process. To understand the intermolecular interactions occurring in the cell we will, for the first time, monitor the - molecular structure and structural changes (dynamics) of nucleotides (miRNAs as well as AONs) in the living cell, and link these in-cell structures to the molecule’s targeting function. Combining existing knowledge of the host in structural and - molecular biology of miRNAs with the experience in methods development in Nuclear Magnetic Resonance (NMR) of the experienced researcher (ER), we will develop a set of robust and reliable in-cell NMR methods to determine cellular concentration, - structure and dynamics within the cell at high resolution. The scope of the method will be demonstrated on: (i) a miRNA, miR-34a, which targets more than 50 different mRNAs, related to cancer and other cellular processes, as well as (ii) an AON drug - candidate in collaboration with AstraZeneca. This project will benefit drug development against various diseases and will enable the ER to contribute to solving today's health problems and develop further towards becoming a future group leader on the - interface of research in academia and industry. - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - RNAatHD - - - H2020-MSCA-IF-2016 - - - 747446 - - - - - THE UNIVERSITY OF WARWICK - - - EUR 195 454,80 - - - Prisoners of war between Bourbon nations and United Kingdom during the 18th Century: ways of life and humanity in misfortune - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Armies of the Ancien Régime reflected not only the society of their time, but also the politics, importance and international weight of their respective nations. Prisoners of war offer a privileged insight into these issues - and, more significantly, into the human and humanitarian feelings of all those involved, politicians and civilians as well as the military. This study will provide a ground-breaking comparative approach to prisoners of war from Britain, Spain and - France during the long 18th century. Through correspondence written by the prisoners themselves as well as letters to/by the authorities, we will chart feelings and views towards the conflicts from those directly involved, revealing alternative views - of war than those imposed by their sovereigns. In what the prisoners conveyed to their families and to the authorities, we can learn much of the conditions of captivity, which varied considerably depending on religion, social status or military rank. - Across the century, we find analogous prisoner of war experiences in different societies and historical periods, but after the French Revolution significant differences begin to emerge because of new political considerations which meant qualitative - changes to the status of prisoners of war, since they were henceforth political prisoners, no longer Ancien Régime ones. Comparing Britain and Spain with France is essential to perfecting our understanding of how the status and experience of - prisoners of war changed between the old order and the new. In brief, this is a study that helps to understand better the changes in the humanitarian measures in war which form the basis of current practice and are at the heart of notions of Human - rights. - - 2019-07-02, ongoing project - - - 2017-07-03 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - PriWa - - - H2020-MSCA-IF-2016 - - - 746995 - - - - - UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6 - UNIVERSIDADE DA CORUNA - QUEEN MARY UNIVERSITY OF LONDON - ASSOCIATION POUR LA RECHERCHE ET LE DEVELOPPEMENT DES METHODES ET PROCESSUS INDUSTRIELS - STICHTING VU - THE UNIVERSITY OF EDINBURGH - - - EUR 2 730 241,94 - - - Deferred Restructuring of Experience in Autonomous Machines - - - EUR 2 784 240,94 - - - France - Spain - United Kingdom - France - Netherlands - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - A holy grail in robotics and artificial intelligence is to design a machine that can accumulate adaptations on developmental time scales of months and years. From infancy through adult- hood, such a system must continually - consolidate and bootstrap its knowledge, to ensure that the learned knowledge and skills are compositional, and organized into meaningful hierarchies. Consolidation of previous experience and knowledge appears to be one of the main purposes of sleep - and dreams for humans, that serve to tidy the brain by removing excess information, to recombine concepts to improve information processing, and to consolidate memory. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.2."> - - - FETPROACT-2-2014 - Knowing, doing, being: cognition beyond problem solving - - - RIA - Research and Innovation action - - - France - - - DREAM - - - H2020-FETPROACT-2014 - - - 640891 - - - - - KOBENHAVNS UNIVERSITET - - - EUR 200 194,80 - - - Global and local star formation with state-of-the-art physics - - - EUR 200 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - New stars form within large turbulent complexes harboring several thousands of solar masses of cold gas: the molecular clouds. The diffuse gas collapses gravitationally and heats up via compression until nuclear fusion - reactions ignite and the star comes to life. The full description involves an intricate interplay between large-scale environmental factors and small-scale processes close to the star, connecting a number of physical mechanisms, including magnetic - fields, self-gravity, radiative transfer, and time dependent chemistry. - - 2017-08-31, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - AdvancedStarForm - - - H2020-MSCA-IF-2014 - - - 659706 - - - - - KOBENHAVNS UNIVERSITET - - - EUR 212 194,80 - - - Mixotrophy among small marine phytoflagellates – prevalence and impact on prokaryotic communities - - - EUR 212 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - Mixotrophy, i.e. the use of photosynthesis and prey uptake for growth, is increasingly recognized as a major trophic strategy for small (≤ 20 µm) phytoflagellates, which are responsible for a significant fraction of global - primary production. In fact, marine primary production in many areas is now thought to be supported by organic P and Fe derived from prey. Despite this, a consistent picture of the overall relevance of bacterivory in open ocean and coastal - mixotrophic small phytoflagellates (MSP) is lacking. Additionally, a strict dichotomy between `phytoplankton´ and `zooplankton´ is still overwhelmingly employed in models predicting the flow of matter and energy through marine systems, leading to - potentially flawed and misleading predictions on ecosystem productivity and the health of global fisheries. This is especially significant when considering that anticipated environmental changes related to climate change are expected to shift the - phototrophy/mixotrophy balance, with largely unknown consequences. The present study will combine culture and field work to 1) determine how shifts in environmental conditions related to e.g. season, influence coastal MSP abundance, identity and - bacterivorous impact on the whole prokaryotic community, and on specific prokaryotic groups, such as unicellular cyanobacteria; and 2) analyze the importance and basic regulation of bacterial uptake for understudied coastal MSP. The proposed project - excellently fuses the expertise areas of the experienced researcher, Dr. Anderson (bacterivory and predator-prey interactions), with the supervisor, Prof. Hansen (mixotrophic phytoflagellates) and the international collaborators, Prof. Jürgens - (protist diversity and microbial food web interactions) and Prof. Scanlan (unicellular cyanobacteria), leading to an optimal exchange of knowledge for a successful project outcome. It will additionally restart and further the promising scientific - career of Dr. Anderson after her maternity break. - - 2017-04-30, closed project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - Denmark - - - MARIS - - - H2020-MSCA-IF-2014 - - - 658882 - - - - - CENTRO EM REDE DE INVESTIGACAO EM ANTROPOLOGIA - CENTRO EM REDE DE INVESTIGACAO EM ANTROPOLOGIA - - - EUR 1 192 144 - - - CRITICAL APPROACHES TO POLITICS, SOCIAL ACTIVISM, AND ISLAMIC MILITANCY IN THE WESTERN SAHARAN REGION - - - EUR 1 192 144 - - - Portugal - Portugal - - - Research Organisations - Research Organisations - - This project proposes an analysis of the reconfigurations established in the socio-political vocabulary of the western Saharan region – southern Morocco, Western Sahara and Mauritania – from the “post-empire” to the - contemporary period. The project should produce an analysis of 1) the social and political structures shared in the region, 2) the local variations of those structures, based on case studies, 3) their specific configurations, based on social markers - such as gender, age, and class, 4) the use of those structures in different historical periods. All these will be under theoretical and ethnographic scrutiny in order to achieve its main goal: 5) to understand the recent articulation of the social - and political structures of the Western Saharan region, with broader and often exogenous political vocabularies. - - - 2021-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Portugal - - - CAPSAHARA - - - ERC-2016-STG - - - 716467 - - - - - ECOLE POLYTECHNIQUE - THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - - - EUR 264 668,40 - - - Solar Wind Heating and Turbulence - - - EUR 264 668,40 - - - France - United States - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Observations of solar wind (SW) turbulence have usually emphasized magnetohydrodynamic (MHD) scales where the Kolmogorov scaling f −5/3 of the magnetic spectra is frequently observed. These spectra are - - 2018-10-31, ongoing project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - France - - - SoWHat - - - H2020-MSCA-IF-2014 - - - 661472 - - - - - UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA - THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - - - EUR 244 269 - - - A mood-indexed database of scores, lyrics, musical excerpts, vector-based 3D animations, and dance video recordings - - - EUR 244 269 - - - Italy - United States - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The project aims at the development of an online database of scores, lyrics and musical excerpts, vector-based 3D animations, and dance video recordings, indexed by mood. Such a taxonomy of relations between the musical, - linguistic and motion domains will be aimed at interactive music systems and music making. For realising the database, digital scores inclusive of lyrics will be gathered from collections of music in the public domain. Music mood classification using - audio and metadata will aim at capturing sophisticated features but using no explicit domain-specific knowledge about a mental state. Datasets will be realised through a cross-modal approach. Validation of the model will be carried out by combining - results from an online game-with-a-purpose, for Internet users, and from intermedia case studies for selected dancers. In further case studies, music works will be realised, also by invited artists, for the evaluation of the database in interactive - music making. An online call for artists to use the database in music making or sound generation will be aimed at extending the evaluation further. The final database will be made available online for further exploitation. The present research will - generate new knowledge for use in next-generation systems of interactive music and music emotion recognition, also contributing to extend the investigation in the broader areas of music making, computational creativity and information retrieval. - - 2018-11-30, ongoing project - - - 2015-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Italy - - - MUSICAL-MOODS - - - H2020-MSCA-IF-2014 - - - 659434 - - - - - UNIVERSITY OF GREENWICH - UNIVERSITA DEGLI STUDI DELL'AQUILA - UNIVERSITEIT TWENTE - SERVICE DEPARTEMENTAL D'INCENDIE ET DE SECOURS DE LA HAUTE-CORSE - ENTENTE POUR LA FORÊT MÉDITERRANÉENNE - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - FUNDACIO D'ECOLOGIA DEL FOC I GESTIO D'INCENDIS PAU COSTA ALCUBIERRE - UNIVERSIDAD COMPLUTENSE DE MADRID - UNIVERSITE DE GENEVE - UNIVERSITA DEGLI STUDI DI PERUGIA - UNIVERSITE CLERMONT AUVERGNE - UNIVERSITE DE TECHNOLOGIE DE COMPIEGNE - UNIVERSITE PARIS DAUPHINE - ECOLE DE MANAGEMENT DE NORMANDIE - ROYAL MELBOURNE INSTITUTE OF TECHNOLOGY*RMIT UNIVERSITY - BUSHFIRE AND NATURAL HAZARDS CRC LIMITED - UNIVERSITY OF MELBOURNE - - - EUR 1 080 000 - - - Geospatial based Environment for Optimisation Systems Addressing Fire Emergencies - - - EUR 1 386 000 - - - United Kingdom - Italy - Netherlands - France - France - France - Spain - Spain - Switzerland - Italy - France - France - France - France - Australia - Australia - Australia - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - - In EU and Australia, every year thousands of square miles of forests and other lands burn due to wildfires. These fires cause important economic and ecological losses, and often, human casualties. Both EU and Australian - governments are aware of how crucial it is to improve wildfires’ management and containment . Scientists from different specialties, both in EU and Australia, have already developed methods and models in order to improve the management and decision - process pertaining to preparedness and response phases in case of bushfire. The present project, named Geospatial based Environment for Optimisation Systems Addressing Fire Emergencies (GEO SAFE), aims at creating a network enabling the two regions - to exchange knowledge, ideas and experience , thus boosting the progress of wildfires knowledge and the related development of innovative methods for dealing efficiently with such fires. - - - 2020-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - United Kingdom - - - GEO-SAFE - - - H2020-MSCA-RISE-2015 - - - 691161 - - - - - UNIVERSITEIT TWENTE - - - EUR 165 598,80 - - - Empowering parents through the development of an online evidence-based mental health promotion school engagement resource - - - EUR 165 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - The promotion of children’s mental health and wellbeing is fundamental to achieving strategic objectives of the EU health policy. Schools are recognised as a key setting to support and enhance children’s social and emotional - wellbeing. Evidence to date indicates that school interventions have the greatest impact when they are focused on linking children, teachers and parents in the promotion of positive mental health. To date, however, there is an absence of research and - resources to assist schools in supporting parental engagement in mental health promotion. The proposed research aims to address this crucial gap in school mental health. The study will adopt a systematic approach to developing an evidence-based - resource for primary schools which is designed to assist school staff in establishing collaborative relationships with parents and align parent and teacher practices in promoting children’s mental health. In order to achieve this, the applicant will - (i) systematically review current evidence on existing school-parent engagement frameworks and resources (ii) develop an online school-parent engagement resource based on the current evidence and consultation with school community stakeholders (iii) - evaluate the implementation and efficacy of the online resource when implemented as part of a whole school mental health intervention that is being trialled in ten primary schools in Twente. This research will be carried out in collaboration with - Prof Bohlmeijer at the Dept. of Psychology, Health and Technology and the Centre of eHealth Research and Disease Management at the University of Twente. The applicant will receive expert training from the Centre of eHealth Research in the development - of technology supported mental health interventions. Under the guidance of Prof Bohlmeijer, the applicant will advance her research, management and networking skills and will generate an innovative research niche producing questions for investigation - beyond the life of this study. - - 2018-01-03, Grant Agreement terminated - - - 2015-07-06 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - EMPOWER - - - H2020-MSCA-IF-2014 - - - 655950 - - - - - UNIVERSITAET BASEL - UNIVERSITAET BASEL - - - EUR 1 498 961 - - - Modular mechanical-atomic quantum systems - - - EUR 1 498 961 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Atomic ensembles are routinely prepared and manipulated in the quantum regime using the powerful techniques of laser cooling and trapping. To achieve similar control over the vibrations of nanofabricated mechanical oscillators - is a goal that is vigorously pursued, which recently led to the first observations of ground-state cooling and quantum behavior in such systems. - - 2020-12-31, ongoing project | - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Switzerland - - - MODULAR - - - ERC-2015-STG - - - 677548 - - - - - THE QUEEN'S UNIVERSITY OF BELFAST - DUBLIN CITY UNIVERSITY - CRANFIELD UNIVERSITY - UNIVERSITAET DUISBURG-ESSEN - IWW RHEINISCH WESTFALISCHES INSTITUT FUR WASSERFORSCHUNG GEMEINNUTZIGE GMBH - TECHNISCHE UNIVERSITAT DORTMUND - SUPREN GMBH - KOBENHAVNS UNIVERSITET - UNIVERSITA DEGLI STUDI DI TORINO - T.E. LABORATORIES LIMITED - - - EUR 3 722 227,71 - - - Improved decision-making in contaminated land site investigation and risk assessment - - - EUR 3 723 227,71 - - - United Kingdom - Ireland - United Kingdom - Germany - Germany - Germany - Germany - Denmark - Italy - Ireland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The REMEDIATE ETN comprises 10 beneficiaries (from 5 EU Member States – the UK, Ireland, Germany, Denmark, and Italy) and 15 partner organisations. The beneficiaries and partner organisations are committed to the provision of - innovative research and training for more cost effective and sustainable remediation of contaminated land. It is a multidisciplinary collaboration between internationally renowned research teams (from both the academic and non-academic sectors) each - with complementary expertise in a wide range of site investigation and risk assessment technologies. 14 Early Stage Researchers (ESRs) will be recruited into the network and will participate in a structured and integrated research and training - programme that will provide them with a highly specific blend of personalised technical and transferable skills. Each research project is designed to benefit the contaminated land sector through development of techniques and tools across a range of - disciplines relating to site investigation and risk assessment, to provide better informed solutions for remediation. The unique provision of joint supervision (from both the academic and non-academic sectors) and non-academic mentoring will - significantly enhance the fellows’ career prospects within the contaminated land sector. The REMEDIATE ETN will strengthen and enhance existing collaborations between the participating beneficiaries and partner organisations resulting in a cohesive - and dynamic network. The output will be a new generation of highly mobile, creative and innovative entrepreneurs with the skills sets necessary to address the technical, economic and social challenges facing the contaminated land sector in Europe, - both now and in the future. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - Remediate - - - H2020-MSCA-ITN-2014 - - - 643087 - - - - - STOCKHOLMS UNIVERSITET - - - EUR 173 857,20 - - - Water Coalitions: A Comparative Analysis of Agenda Implementation Strategies in Peru and Brazil through the Study of Basin Councils. - - - EUR 173 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - This project aims at establishing and explaining the reasons behind coalition formation and coalition sustainability in water management. It sets its scope on selected basin councils operating in two Latin American countries, - Peru and Brazil. Both countries, and the Latin American region in general, have faced numerous conflicts around water management in the past. The relationships between the state and civil society movements over water have been presented as - dichotomous, dismissing the complexities of the ‘street-level bureaucrat’ category. To fill in that gap, this project asks: ‘what kind of coalitions do bureaucrats and social leaders establish to institutionalise and strengthen specific visions of - water management?’ Coalitions are defined as groups of actors who have joined forces to accomplish common objectives. The project investigates (i) the types and characteristics of coalitions between bureaucrats and activists, (ii) the factors that - explain coalition formation and membership and, (iii) the relationships between different coalitions. Peru and Brazil are similarly organized through basin councils and a national water authority. Yet, they have three important differences that would - lead to fruitful comparison: the level of decentralization, the vision of water institutionalised and, the approach to social participation. This study will shed light on the power differentials between bureaucracies and on the tools available for - weak bureaucracies to advance in their agendas. In order to explore these issues I will combine the Advocacy Coalition Framework with the Social-Ecological Systems framework and analyse the data through a cross-case methodology. The project will - produce a model on coalition formation and behaviour. Investigating coalition formation and behaviour is urgent if we are to provide multi-actor water governance the tools to perform better than traditional approaches. - - 2017-09-06, closed project - - - 2015-09-07 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - Water Coalitions - - - H2020-MSCA-IF-2014 - - - 660394 - - - - - UNIVERSITY OF PLYMOUTH - UNIVERSITEIT GENT - THE UNIVERSITY OF LIVERPOOL - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 288 000 - - - Integrating isotopic techniques with Bayesian modelling for improved assessment and management of global sedimentation problems - - - EUR 288 000 - - - United Kingdom - Belgium - United Kingdom - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - This international RISE programme brings together EU, North American, African and Asian scientists to deliver a powerful tool for sediment management. Siltation of river channels, lakes and reservoirs presents a credible - threat to river basin ecosystem service provision and water security. River silt originates in the catchment and the primary driver for mobilisation and translocation downstream is agriculture where loss of soil from slopes threatens food security. - Knowledge of sediment source, transfer and residence time dynamics is critical to inform management for future food and water security and cutting-edge nuclear techniques have been developed in a joint UN Food and Agriculture Organisation and - International Atomic Energy Agency Coordinated Research Programme to trace river silt back to source. However, the game change in isotopic biogeochemical tracer sophistication has led to a step change in data complexity. While these datasets capture - real world complexity in time and space, the conventional statistical approaches to quantify sediment provenance from the tracer data do not. This severely limits the power of isotopic techniques for sediment source apportionment. Advances in - ecological source apportionment models based on Bayesian statistics, however, present opportunity. New models, i.e. MixSIAR, have been shown to appropriately address such variability in a quantitative way and, if tailored to river basin sediment - tracer data offer to address the above challenge. The central goal is to marry together the strengths of isotopic sediment tracer technology in the EU with ecological source apportionment models developed by North American scientists to deliver a - powerful tool to combat threats to global food and water security. The tool will be showcased through its application in water-supply catchments where diffuse sediment and nutrient pollution from agriculture threatens food, water and, through - siltation of of HEP dams, energy security. - - 2017-06-30, closed project | - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - United Kingdom - - - IMIXSED - - - H2020-MSCA-RISE-2014 - - - 644320 - - - - - UPPSALA UNIVERSITET - - - EUR 233 111,60 - - - Temporality of permanence –material and socio-spatial practices in African urbanism - - - EUR 233 111,60 - - - Sweden - - - Higher or Secondary Education Establishments - - The constructed materiality of African urbanism can be seen in buildings and the urban layout, especially when they aspire to permanence by building in stone. These built environments have mostly been analysed through the - rather static lens of individual periods and social forces, resulting in uniformly interpreted organic growth (for pre-colonial periods), or as in stages of progress towards the fulfilment of a grand master plan (predominantly in the colonial and - post-colonial era). This project seeks to explore the social temporality of African urbanism against the context of its material complements from the perspectives of a range of social and human sciences, in order to obtain a dynamic picture from - before to after the colonial era. I aim to provide analyses relevant to the ever more pressing issues of urban ethnic/social coexistence and the implications of urban development. - - 2018-05-13, ongoing project | - - - 2015-09-14 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Sweden - - - TEMPEA - - - H2020-MSCA-IF-2014 - - - 656767 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 159 460,80 - - - PULsar Science Across The Electromagnetic Spectrum - - - EUR 159 460,80 - - - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Over the last 50 years the study of pulsars has advanced our scientific knowledge over an incredibly broad range of topics, from particle physics, where they provide the only means of experimentally testing theories that - describe the behaviour of matter at densities greater than those in an atomic nucleus, to enabling exquisitely precise tests of gravity. Since their initial discovery, over 2000 pulsars have been found in surveys worldwide, and observed from 100 MHz - up to TeV gamma-ray energies, however ten times more than this are expected to be observable in our Galaxy. - - 2019-09-30, Grant Agreement terminated - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - PULSATES - - - H2020-MSCA-IF-2016 - - - 748941 - - - - - KAROLINSKA INSTITUTET - KAROLINSKA INSTITUTET - - - EUR 2 443 952,50 - - - Decomposition of pain into celltypes - - - EUR 2 443 952,50 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Almost 20% of the population has an ongoing pain problem. Pain is caused by a complex recruitment of different types of sensory neurons with different response-profiles and hence, the integrated response of an assembly of - different neuronal types results in pain. Due to technical limitations, a system-wide approach to resolve the complexity of cell types and their involvement in the development of pain has yet not been tried. - - 2022-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Sweden - - - PainCells - - - ERC-2016-ADG - - - 740491 - - - - - UNIVERSITA DEGLI STUDI DI CAGLIARI - KINGSTON UNIVERSITY HIGHER EDUCATION CORPORATION - THE WALT DISNEY COMPANY (SWITZERLAND) GMBH - DEUTSCHE TELEKOM AG - UNIVERSITY OF PLYMOUTH - NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU - HOLOGRAFIKA HOLOGRAMELOALLITO FEJLESZTO ES FORGALMAZO KFT - - - EUR 2 883 122,64 - - - innovative Quality Of Experience maNagement in Emerging mulTimedia services - - - EUR 2 883 122,64 - - - Italy - United Kingdom - Switzerland - Germany - United Kingdom - Norway - Hungary - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The realization of the paradigm of Internet anywhere, anytime and any-device and the diffusion of end-user multimedia devices with powerful and user-friendly capabilities such as smartphones, tablets PCs, mobile gaming - terminals and e-books, are leading to the proliferation of a significant amount of emerging multimedia services: immersive environments, mobile online gaming, 3D virtual world, book/newspaper consumption, social networking, IPTV applications, just to - cite a few. Some of these services have already reached a major market success, such as the case of newspaper/magazine mobile readers and smartphone multimedia apps. Their success has been achieved especially because a user-centered approach has been - followed to design the whole process of content production, service activation, content consumption, service management and updating. From these considerations it arises that management of the Quality of Experience (QoE) is undoubtedly a crucial - concept in the deployment of future successful services and it is straightforward to be understood but complex to be implemented in real systems, since there are many variables which will affect QoE, and these variables are changeable and span - multidisciplinary areas including multimedia signal processing, communications, computer networking, psychology and sociology. - - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Italy - - - QoE-Net - - - H2020-MSCA-ITN-2014 - - - 643072 - - - - - THE UNIVERSITY OF EXETER - - - EUR 195 454,80 - - - PEATland modelling for global carbon cycle and climate models - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Prediction of future climate change can only be achieved through models of the global climate system and its interactions with earth system processes. The reliability of the predictions depends on building the best - understanding of these processes. Changes in the global carbon cycle are a source of major uncertainty in models and terrestrial carbon stored in peatlands is a critical element of this. The action proposed here will bring state-of-the-art process - modelling into global vegetation models that are used in projections of future climate change. An improved understanding of peatland dynamics and functions will also have implications for management and climate mitigation strategies for wetlands, - agriculture, land-use, and energy. I have worked extensively in North America on one of the most sophisticated peatland process models. I will work with Dan Charman and Angela Gallego-Sala at Exeter to build this model in to one of the most widely - used dynamic global vegetation models so that peatlands and their carbon balance are better represented within global climate models. The work will thus allow quantification of the impact of peatlands on the global carbon cycle in the past and in the - future. The action will bring top level expertise in peatland modelling back to Europe and build a bridge between the North American peatland modelling community and those in Europe. It will expose me to training and development in the necessary - skills, people and laboratories to take this work forward independently in a European institution in the future. The supervisors at Exeter will develop their already strong record in carbon cycle and climate modelling and further develop links with - other European workers and key groups in North America. Overall the action will provide a secure launch pad for my career, bring cutting edge skills to Europe and build stronger and long lasting linkages between European and North American science. - - 2018-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - United Kingdom - - - PEATmod - - - H2020-MSCA-IF-2014 - - - 658041 - - - - - UNIVERSITAET BASEL - - - EUR 187 419,60 - - - Cold atom-semiconductor quantum interface - - - EUR 187 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - A group III/V semiconductor quantum dot will be interfaced with an ensemble of ultracold alkali atoms (first group). This interface will allow to combine efficient single photon generation in quantum dots with the excellent - properties of cold atom quantum memories to build a key element for future high-speed quantum networks. - - - 2018-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - 3-5-FIRST - - - H2020-MSCA-IF-2015 - - - 702304 - - - - - UNIVERSITY OF ESSEX - - - EUR 195 454,80 - - - Impacts of Nanoparticles on microphytobenthic Biofilms and consequences on the Carbon cycle - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Intertidal and shallow subtidal zones are key areas for biochemical transformations, and particularly they play a crucial zone in the carbon cycle. In soft-bottom areas, most primary production is performed by photosynthetic - microorganisms organised in biofilms, and called microphytobenthos. The organic matter they produce is rapidly respired by bacteria or consumed by higher trophic levels. Together, microphytobenthos and bacteria realise most carbon transformation in - these areas, and are therefore important groups to study in a view to understand carbon cycling in coastal zones. Coastal areas are currently under influence of numerous stressors linked to anthropogenic effects. The impacts of ‘well established’ - pollutants, e.g. metals, oils, nitrogen, are fairly well understood; however there is now evidence that new compounds, products of advanced technology, have the potential to disrupt the environment. The aim of this project is to understand how a - recently developed family of compounds, namely nanoparticles (NPs), influences the development of biofilms and their impact on the carbon cycle. NP concentrations are increasing dramatically in the environment, but their effect on organisms and - ecosystems is currently poorly described. Yet, genotoxic and cytotoxic effects of NPs have been demonstrated, including on microorganisms. In this project, laboratory and field experiments will be performed to characterise the effects of NPs on - microphytobenthos and bacteria, on their trophic interactions and on their roles in carbon and nutrient cycles. Two common types of NPs will be tested in a wide range of environmental conditions, to decipher in which conditions NPs are more or less - harmful to organisms and processes. Such understanding will allow developing strategies to reduce the impacts of NPs and will be beneficial to environment and human well-being in EU and elsewhere. - - 2018-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - NanoBioCar - - - H2020-MSCA-IF-2015 - - - 702217 - - - - - UNIVERSITY OF PLYMOUTH - - - EUR 195 454,80 - - - Donating Robots a Theory of Mind - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - This project aims to advance the science and technology of meta-cognition in social robotics. During social interactions, humans use powerful cognitive mechanisms to represent and interpret what others know or intend. Doing so - helps us respond appropriately in social interactions: we use a combination of sensory perception together with internal models of what others are (and will be) doing and thinking. We believe these capabilities to be equally important for social - robots, a type of robot which is intended to interact with people. Endowing robot with skills to "read the minds" of others is not only key to build next-generation assistive and industrial robots, but also presents a considerable research challenge. - A challenge with tremendous benefits but few successes to date. - - 2017-09-06, closed project - - - 2015-09-07 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - DoRoThy - - - H2020-MSCA-IF-2014 - - - 657227 - - - - - UNIVERSITY OF PLYMOUTH - - - EUR 195 454,80 - - - Neurophenomenology of Mental Imagery - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The NeuPheMi project presents a novel approach in the neuroscientific study of mental imagery. Mechanisms of mental imagery are not yet well understood and while traditional approaches investigated their neural correlates - based mostly on problem-solving tasks, NeuPheMi proposes to shed the light on the neural correlates of experiencing mental imagery. By taking into account the subjective experience and using electroencephalography and brain stimulation techniques to - investigate the dynamic of neuronal activity during mental imagery in an original neurophenomenological approach, NeuPheMi is expected to bring a better understanding of the neuronal basis of mental imagery and extend our comprehension of human - consciousness. - - - 2018-03-21, ongoing project - - - 2016-03-22 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - NeuPheMi - - - H2020-MSCA-IF-2014 - - - 660711 - - - - - CENTRO DE INVESTIGACION ECOLOGICA YAPLICACIONES FORESTALES CONSORCIO - - - EUR 158 121,60 - - - A novel approach to determine canopy nitrification in the phyllosphere of European forests: combining multiple isotope tracers and proteogenomic techniques - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - Forest canopies play a significant role in regulating carbon and water exchanges with the atmosphere, with profound effects on our climate. However, their role in altering the chemical composition of precipitation and, - consequently, the nutrient cycling within a forest has been less investigated. This is particular relevant for nitrogen (N)-limited forests in the Northern hemisphere, which have been exposed to a rapid human-induced increase in Ndep over the last - decades. Much of the scientific attention has been focused on the role of Ndep in enhancing forest C-sink, while we still need to elucidate the fate of Ndep when entering forest and its contribution to N cycling. In particular, it is still not clear - whether Ndep is retained, taken up and/or altered by biological transformations when interacting with tree canopies. By applying a quadruple isotope approach I recently demonstrated the occurrence of in-canopy biological nitrification of atmospheric - N for UK forests at high Ndep. Hence, NITRIPHYLL intends to extend the multiple isotope approach a) to enlarge the range of conditions under which the process is demonstrated to occur, b) to investigate difference between species in the proportion of - microbiologically-derived NO3 and c) the reasons of these differences. Furthermore, by using proteo-genomic techniques we aim to characterize phyllosphere microbial communities involved in canopy nitrification. We will consider i) forests along a - gradient of climate and Ndep within the well established EU-ICP forest network and ii) existing N manipulation experiments. NITRIPHYLL for the first time merges two separate research avenues, i.e., the investigation of canopy nitrification with the - study of the occurrence, abundance and diversity of bacteria communities in the phyllosphere. Thus, the project will contribute to providing a deeper understanding of how the phyllosphere affects the N, and consequently C, cycling within forests in - relation to climate and Ndep. - - 2018-06-05, ongoing project - - - 2016-06-06 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Spain - - - NITRIPHYLL - - - H2020-MSCA-IF-2015 - - - 705432 - - - - - UNIVERSITEIT TWENTE - UNIVERSITEIT TWENTE - - - EUR 1 500 000 - - - Robot-Assisted Flexible Needle Steering for Targeted Delivery of Magnetic Agents - - - EUR 1 500 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Diagnostic agents are currently injected into the body in an uncontrolled way and visualized using non-real-time imaging modalities. Delivering agents close to the organ and magnetically guiding them to the target would permit - a myriad of novel diagnostic and therapeutic options, including on-site pathology and targeted drug delivery. Such an advance would truly revolutionize minimally invasive surgery (MIS). Presently MIS often involves manual percutaneous insertion of - rigid needles. These needles deviate from their intended paths due to tissue deformation and physiological processes. Inaccurate needle placement may result in misdiagnosis or ineffective treatment. Thus, the goal of ROBOTAR is to design a robotic - system to accurately steer flexible needles through tissue, and enable precise delivery of agents by magnetically guiding them to a designated target. - - 2020-05-31, ongoing project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - ROBOTAR - - - ERC-2014-STG - - - 638428 - - - - - UNIVERSITAET BASEL - UNIVERSITAET BASEL - - - EUR 2 490 700 - - - Directed Evolution of Artificial Metalloenzymes for In Vivo Applications - - - EUR 2 490 700 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In the past decade, artificial metalloenzymes (AMs) have emerged as an attractive alternative to the more traditional enzymes and homogeneous catalysts. Such hybrid catalysts result from the incorporation of an abiotic metal - cofactor within a macromolecule (protein or oligonucleotide). Artificial metalloenzymes combine attractive features of both homogeneous catalysts and enzymes, including the possibility to genetically optimize the catalytic performance of - new-to-nature organometallic reactions. Can artificial metalloenzymes become as catalytically efficient as naturally-evolved metalloenzymes, even in complex biological mixtures? Herein, we outline our efforts to address this challenge by localizing - and evolving AMs within the periplasm of Escherichia coli. - - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Switzerland - - - DrEAM - - - ERC-2015-AdG - - - 694424 - - - - - UNIVERSITEIT TWENTE - - - EUR 165 598,80 - - - A community of surface bots for creative storytelling - - - EUR 165 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Interactive digital storytelling systems can be used to foster the development of creativity skills and enhance social awareness on our societal issues, aspects recognized to be strategic for our own future sustainability and - competitiveness. However, current interactive storytelling approaches face important limitations in the implementation of digital characters. On the one hand, some systems provide very capable socially virtual agents used as characters, but enacted - in a virtual world where technology is rather a barrier to effective creative thinking and collaboration. On the other hand, settings with tangible objects facilitate discussion in groups as well as the development of relevant critical social skills, - but with characters unable to show advanced smart capabilities to enrich storytelling for a more effective process. - - 2018-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - COBOTNITY - - - H2020-MSCA-IF-2015 - - - 701991 - - - - - UNIVERSITEIT TWENTE - UNIVERSITEIT TWENTE - - - EUR 1 500 000 - - - NanoPacks: Assembling nanoparticles via evaporation-driven droplet collapse for ultrasensitive detection techniques - - - EUR 1 500 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The foundation of nanophotonics and nanoplasmonics has boosted the development of ultrasensitive detection techniques. Some of these techniques, such as Surface Enhanced Raman Spectroscopy or Surface Enhanced Fluorescence, are - able to detect femtomolar concentrations of analytes or even single molecules, only relying on the adsorption of the analytes on a nanostructured surfaces. - - - 2021-07-31, ongoing project - - - 2016-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - NanoPacks - - - ERC-2015-STG - - - 678573 - - - - - UNIVERSITAET BASEL - UNIVERSITAET BASEL - FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION - - - EUR 2 499 250 - - - Signal Transduction and Epigenetic Mechanisms of Breast Cell Plasticity and Cancer - - - EUR 2 499 250 - - - Switzerland - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - Breast cancer is diagnosed in ~1.4 million women worldwide and ~500,000 lives are lost to the disease annually. Patients may do well after surgery and initial treatment, but drug resistant and fatal metastases often develop. - Improved treatment options are urgently needed. The connecting thread of this project is the identification of epigenetic drivers of breast cell fate, tumor heterogeneity and metastasis. - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Switzerland - - - STEM-BCPC - - - ERC-2015-AdG - - - 694033 - - - - - UNIVERSITY OF ESSEX - UNIVERSITY OF ESSEX - - - EUR 2 499 471 - - - Disagreements and Language Interpretation - - - EUR 2 499 471 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Natural language expressions are supposed to be unambiguous in context. Yet more and more examples of use of expressions that are ambiguous in context, yet felicitous and rhetorically unmarked, are emerging. In my own work, I - demonstrated that ambiguity in anaphoric reference is ubiquitous, through the study of disagreements in annotation, that I pioneered in CL. Since then, additional cases of ambiguous anaphoric reference have been found; and similar findings have been - made for other aspects of language interpretation, including wordsense disambiguation, and even part-of-speech tagging. Using the Phrase Detectives Game-With-A-Purpose to collect massive amounts of judgments online, we found that up to 30% of - anaphoric expressions in our data are ambiguous. These findings raise a serious challenge for computational linguistics (CL), as assumptions about the existence of a single interpretation in context are built in the dominant methodology, that depends - on a reliably annotated gold standard. - - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - DALI - - - ERC-2015-AdG - - - 695662 - - - - - UNIVERSITEIT TWENTE - UNIVERSITEIT TWENTE - - - EUR 1 500 000 - - - Information-age microscopy for deep vision imaging of biological tissue - - - EUR 1 500 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Modern biology could not exist without the optical microscope. Hundreds of years of research have seemingly developed microscopes to perfection, with one essential limitation: in turbid biological tissue, not even the most - advanced microscope can penetrate deeper than a fraction of a millimetre. At larger depths light scattering prevents the formation of an image. DEEP VISION takes a radically new approach to microscopy in order to lift this final limitation. - - 2021-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - DEEPVISION - - - ERC-2015-STG - - - 678919 - - - - - UNIVERSITAET BASEL - UNIVERSITAET BASEL - - - EUR 2 499 500 - - - Signal Integration by Gene Regulatory Landscapes - - - EUR 2 499 500 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Identification of the molecular mechanisms by which gene regulatory landscapes integrate diverse signaling inputs into a robust and dynamic transcriptional output is key to a comprehensive mechanistic understanding of the - systems that govern vertebrate organogenesis. We will tackle this by taking advantage of our in-depth knowledge of the self-regulatory signaling systems controlling vertebrate limb development. To capture the dynamics by which the major signaling - pathways (BMP, SHH, WNT, FGF) interact to control gene expression, we will profile chromatin architecture, epigenetic marks and the interaction kinetics of transcriptional effectors with cis-regulatory modules (CRMs) during mouse limb bud - development. First, we will focus on the Grem1 gene regulatory landscape, as this BMP antagonist is a key node in the system and its spatio-temporal expression is regulated by all four pathways. This analysis will capture the temporal activity of all - CRMs in the Grem1 landscape and reveal the ones that are targets of one or several signaling pathways. The functional requirements of single and multiple CRMs with redundant functions will be assessed by gain- and loss-of-function genetics in mice. - This analysis together with in silico simulations of the relevant interactions aims to reveal the underlying regulatory logic. Second, the genome-wide datasets will be used to analyse the gene regulatory landscapes of signals involved in - epithelial-mesenchymal and auto-regulatory feedbacks. Third, the trans-cis regulatory alterations underlying the evolutionary diversifications that resulted in digit loss and reductions will be functionally studied by comparative analysis of mouse, - bovine, pig and chicken limb buds. Finally, as aberrant Grem1 expression predisposes to various diseases and cancers, we will study the trans-cis regulatory alterations that affect the Grem1 landscape in a mouse model of SHH-induced cerebellar - medulloblastomas, which depends on aberrant Grem1 expression. - - 2021-07-31, ongoing project - - - 2016-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Switzerland - - - INTEGRAL - - - ERC-2015-AdG - - - 695032 - - - - - UNIVERSITAET BASEL - UNIVERSITAET BASEL - - - EUR 1 744 921 - - - Holding hands: cell-cell junctions in breast cancer metastasis and resistance to therapy - - - EUR 1 744 921 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Breast cancer is the most common cancer in women, resulting in as many as 500000 deaths per year worldwide. Patients with breast cancer die unequivocally because of the development of incurable distant metastases and not - because of symptoms related to the primary site. Understanding the complex, yet fundamental mechanisms driving breast cancer metastasis is critical to develop therapies tailored to this disease. - - 2021-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Switzerland - - - HOLDING-HANDS - - - ERC-2015-STG - - - 678834 - - - - - CENTRO DE INVESTIGACION ECOLOGICA YAPLICACIONES FORESTALES CONSORCIO - - - EUR 158 121,60 - - - Understanding soil fertility impacts on terrestrial biomass production in a changing environment - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - The feedback between climate and the land carbon (C) cycle poses one of the largest uncertainties in climate change projections. FIBER targets the unresolved challenge for Dynamic Global Vegetation Models (DGVM) to simulate - effects of soil fertility and nutrient deposition on biomass productivity (BP) and the land C balance. Accumulating evidence documents how plants adjust their growth strategies and C allocation under multiple limiting resources. Current DGVMs lag - behind these new insights, produce widely diverging results for C cycling and nutrient limitation under future scenarios and fail to explain the observed land C sink. This work will provide a new global modelling approach to simulating flexible plant - C allocation following optimality principles. A better understanding of the controls on BP is crucial for assessing climate change impacts on ecosystem services and to reduce uncertainty in C cycle and climate change projections. - - 2019-02-27, ongoing project - - - 2017-02-28 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - FIBER - - - H2020-MSCA-IF-2015 - - - 701329 - - - - - UNIVERSITEIT TWENTE - UNIVERSITEIT TWENTE - - - EUR 2 250 000 - - - Vascular Engineering on chip using differentiated Stem Cells - - - EUR 2 250 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Organs-on-chip hold great promise for the creation of complex and realistic disease models while having the potential to refine, reduce and (partly) replace existing animal models (3R principle). Of all organs, vasculature is - extremely well-suited to realize on-chip since it pervades the whole organism, is present in all other organs, its malfunctioning plays a role in many diseases and finally is ideally suited to approach with microfabrication and microfluidic - technologies. In the VESCEL program we propose the development of innovative technologies enabling the use of differentiated human induced pluripotent stem cells (hiPSC) to engineer blood vessels on chip that constitute realistic disease models for - thrombosis and neurodegenerative (ND) diseases. The use of differentiated hiPSC allows the realization of blood vessels based upon patient-specific material, without the need for biopsies, while development of integrated microsensors for small - molecules (pH, O2, NO) offers the possibility of on-line monitoring. To optimize the hiPSC differentiation conditions we propose the use of a microdroplet platform, that combines high-throughput capability (up to 1000 cells/s) with control of single - cell microenvironment. We will also develop a new flexible technology for real 3D vasculature realization using advanced 3D printing technologies. These four innovative technology developments will be integrated in two biomedical applications to - study two important classes of diseases, thrombosis and neurodegenerative (ND) diseases. For thrombosis we focus on the study of parameters such as blood pressure and stenosis as well as effects of drugs on thrombus formation, while for ND diseases - study we will use a blood brain barrier (BBB) model to investigate nanoparticle and peptide transport across the BBB for a form of Alzheimer’s disease, as well as leukocyte extravasation for multiple sclerosis (MS). - - 2020-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Netherlands - - - VESCEL - - - ERC-2014-ADG - - - 669768 - - - - - UNIVERSITEIT TWENTE - UNIVERSITEIT TWENTE - - - EUR 2 000 000 - - - Rare earth doped novel on-chip sources - - - EUR 2 000 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The development of compact, low cost, power efficient, tunable lasers and frequency combs spanning large bandwidths, exhibiting excellent output beam characteristics, such as the ones achieved in solid-state sources, and - expanding the wavelength ranges of by typical solid-state materials, will greatly benefit application fields such as optical sensing, spectroscopy, metrology and telecommunications. - - 2020-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - RENOS - - - ERC-2014-CoG - - - 648978 - - - - - UNIVERSITAET BASEL - UNIVERSITAET BASEL - - - EUR 2 496 460 - - - Alternative Splicing Codes for Synaptic Specificity - - - EUR 2 496 460 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Neuronal networks represent an impressive example of highly organized complex systems. Sperry postulated that selective neuronal connectivity is achieved by chemoaffinity labels. Several such labels for axon guidance and - topographic mapping have been defined. However, until recently, molecules that direct the recognition of synaptic partners and functional specification of synapses have remained obscure. - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Switzerland - - - SPLICECODE - - - ERC-2015-AdG - - - 694584 - - - - - CENTRO DE INVESTIGACION ECOLOGICA YAPLICACIONES FORESTALES CONSORCIO - - - EUR 158 121,60 - - - Hydraulic functional traits as determinants of forest function and drought responses. Putting xylem and phloem attributes into the functional trait map. - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - Forests provide key ecological services such as the regulation of energy, carbon and water balances from local to global scale. These are however under severe pressure due to climate and land use changes, especially in the - Mediterranean basin where limited water availability is prominent. It is thus crucial to identify the forest species and areas that are likely to be more vulnerable to reduced water availability and establish how changes in forest composition and - structure will impact key ecosystem services. In this project, we will use the functional trait concept to bridge between tree, population, species and forest level and as such enlarge our capacity to predict where and when dramatic changes in forest - ecosystem services are likely to occur, especially focusing on the role of phloem and parenchyma tissue in tree and forest functioning in relation to drought. Our objectives are to (i) measure phloem and parenchyma traits of 104 populations of 7 - dominant tree species in Catalonia and Portugal, study the relationships between these traits and other hydraulic and functional traits and quantify their variability along gradients in water availability, (ii) integrate phloem and parenchyma traits - in the theoretical framework describing tree responses to drought, (iii) determine which combination of traits is the best predictor of drought resistance at intra- and interspecific level and (iv) test how and to which extent variability in phloem - and parenchyma traits influences forest performance at different ecological scales and forest vulnerability under climate change scenarios. Classical wood anatomy and plant physiology methods will be used as well as novel 3D techniques and recently - developed models will be combined and extended. Our results will contribute to the knowledge needed to design effective strategies to deal with climate change. Transferring it to managers and policy makers, as well as to the society at large, is thus - a focus of the proposal. - - 2018-01-14, closed project - - - 2016-01-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - PHLOEMAP - - - H2020-MSCA-IF-2014 - - - 659191 - - - - - CARDIFF METROPOLITAN UNIVERSITY - - - EUR 251 857,80 - - - Understanding blood pressure and vascular haemodynamics in implanted Left Ventricular Assist Device patients. - - - EUR 251 857,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Background: Advanced heart failure (HF) is a growing health problem in the European Union (EU). Consequently, a growing number of HF patients now depend on state-of-the-art continuous flow Left Ventricular Assist Devices - (cf-LVAD) as a bridge to transplant or as a means of destination therapy. Since the introduction and usage of cf-LVAD’s rather than traditional pulsatile LVAD’s, survival rates have significantly improved. However, an increased number of - side-effects, including stroke and microvascular bleeding, have been reported. Suggested mechanisms associated with these side effects is lack of pulsatile pressure and flow throughout the system, however there are currently no data on macro/micro - haemodynamics in these patients. - - 2019-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - HIT-LVAD - - - H2020-MSCA-IF-2015 - - - 705219 - - - - - UNIVERSITAET BASEL - UNIVERSITAET BASEL - - - EUR 1 009 351 - - - Fluid Flows and Irregular Transport - - - EUR 1 009 351 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Several important partial differential equations (PDEs) arising in the mathematical description of physical phenomena exhibit transport features: physical quantities are advected by velocity fields that drive the dynamics of - the system. This is the case for instance for the Euler equation of fluid dynamics, for conservation laws, and for kinetic equations. - - 2021-05-31, ongoing project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Switzerland - - - FLIRT - - - ERC-2015-STG - - - 676675 - - - - - UNIVERSITY OF PLYMOUTH - SOFTBANK ROBOTICS EUROPE - - - EUR 1 345 614,84 - - - Applications of Personal Robotics for Interaction and Learning - - - EUR 1 345 614,84 - - - United Kingdom - France - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The aim of personal robotics is to design companion robots that can live and interact with people in a very intuitive way. This requires designing robots that are capable of adapting to the human users, via learning during - interaction. This proposal aims at the timely establishment of the first European Industrial Doctorate in “Applications of Personal Robotics for Interaction and Learning” (APRIL) to train future researchers and engineers for the emerging field of - personal robotics. APRIL strategically adopts a key entrepreneurial ethos which will equip PhD students with radical cross-sector and interdisciplinary skills and mind-set, by combing research on developmental and social cognitive systems with - hands-on experiments on the application of human-robot interaction and assistive systems. APRIL is the result of the strategic synergies of Plymouth University Centre for Robotics and Neural Systems with its international leadership and reputation as - UK and European hub in cognitive developmental robotics and human-robot interaction, and with Aldebaran Robotics A-Lab R&D Division which has the world leading market position in the personal robotics industry with the robots NAO and Pepper. This - is complemented by six international partners from industry (SONY Corporation, MetraLabs GmbH), academia (Osaka, Humboldt Berlin) and robot users (San Raffaele Hospital Milan and SSSA DomoCasa Pisa). The doctoral training strategy of the EID will - implement the latest innovative PhD training approaches of situative and social constructivist learning theories with a unique Coaching Programme for a tailored Individual Skills Development Plan, peer-support and student-centred cohort activities, - as well as a strong leadership skills programme for continuous professional development. The two beneficiaries will contribute with a pool of over 12 academic and industry supervisors and will fund 5 additional PhD bursaries to match the EID cohort - of the 5 Marie Skłodowska-Curie funded ESR - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-EID - Marie Skłodowska-Curie Innovative Training Networks (ITN-EID) - - - MSCA-ITN-EID - European Industrial Doctorates - - - United Kingdom - - - APRIL - - - H2020-MSCA-ITN-2015 - - - 674868 - - - - - THE UNIVERSITY OF SHEFFIELD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - HELIA PHOTONICS LTD - TECHNISCHE UNIVERSITAET MUENCHEN - UNIVERSITAT KONSTANZ - ATTOCUBE SYSTEMS AG - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - TECHNISCHE UNIVERSITEIT DELFT - Eidgenössische Technische Hochschule Zürich - UNIVERSITAET BASEL - KOBENHAVNS UNIVERSITET - - - EUR 3 965 414,04 - - - Nanoscale solid-state spin systems in emerging quantum technologies - - - EUR 3 965 414,04 - - - United Kingdom - United Kingdom - United Kingdom - Germany - Germany - Germany - France - Netherlands - Switzerland - Switzerland - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This network brings together world-leading experts in nano-science and technology from 6 European countries in order to achieve breakthroughs in understanding and successful utilization of nanoscale solid-state spin systems in - emerging quantum technologies. The proposed innovative science in the supra-disciplinary field of physics and applications of spin nano-systems will underpin breakthrough developments in quantum computing, quantum communications and networks, and - nano-imaging. Important innovative step consolidating the joint effort of the whole consortium is the focus on crystalline solids where magnetic interactions of electron spins with lattice nuclei are negligible and well-controlled. We will develop - electrically-controlled spin-quantum-bits (qubits) in Si-Ge quantum dots and nanowires; will optically manipulate spin impurities in diamond in applications for quantum computing and networks and in nano-magnetometry; will achieve new understanding - of quantum phenomena due to the spin-valley coupling in atomically thin 2D semiconductors, an emerging class of materials with a promise for quantum technologies. Research training to 15 early stage researchers will be delivered by 14 academic and 7 - industrial groups. Network-wide training course in transferable skills will be specially developed and delivered by the Think Ahead (Sheffield), an award winning initiative at the University of Sheffield (award by the Times Higher Education, 2014). - Current proposal is designed to advance this multi-disciplinary research field significantly beyond the state-of-the-art, and train a new cohort of researchers capable of developing spin-based solid-state quantum technologies towards real-life - applications in the next 5 to 10 years. - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - Spin-NANO - - - H2020-MSCA-ITN-2015 - - - 676108 - - - - - STICHTING IHE DELFT - - - EUR 190 862,10 - - - Visualizing aquifers: sustainable water use in the Atacama Desert and beyond - - - EUR 190 862,10 - - - Netherlands - - - Research Organisations - - Billions of people rely for their everyday existence on aquifers. The invisibility of these waters, however, poses formidable challenges for those who rely on them: locating, measuring and controlling aquifers is complex and - precarious, yet of utmost importance for human survival in many parts of the world. The overall aim of the proposed project is to explore the vital connections between humans and aquifers in everyday life. Building on trans-disciplinary studies that - consider water as the contested nexus of social and political affairs, this project explores groundwater as both mediating and generating diverse ‘groundwater practices’: as an invisible resource, groundwater requires visualization; as an underground - supply, it calls for innovative extractive techniques; as a finite good, groundwater needs to be regulated and controlled; and as a practical everyday resource, it sustains irrigation, sanitation, and human consumption. Through ethnographic fieldwork - in Atacama Desert of Northern Chile, this project will develop an analytical framework to understand how social relations are affected by various groundwater practices. The proposed research will explore such practices with a focus on the effects - that the visualization of aquifers has on socio-economic and eco-political inequalities. Through transdisciplinary training at the Universidad Católica del Norte, I will strengthen methodological skills to study the groundwater practices of - indigenous communities, hydro-geologists and state administrators. I will transfer the acquired skills to the UNESCO-IHE Institute for Water Education, where I will strengthen understandings of the dynamics among groundwater practices, power, and - culture, providing trans-disciplinary input for policymakers engaged in the design and realization of the Sustainable Development Goals. Findings will be disseminated among policymakers, academics, and broader audiences concerned with environmental - sustainability. - - 2019-06-30, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Netherlands - - - INVISIBLE WATERS - - - H2020-MSCA-IF-2015 - - - 706346 - - - - - UNIVERSITY OF EAST ANGLIA - UNIVERSITAT DE LES ILLES BALEARS - AARHUS UNIVERSITET - UNIVERSITY OF PLYMOUTH - FRIEDRICH-SCHILLER-UNIVERSITAT JENA - NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU - QUALISYS AB - WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER - CONSIGLIO NAZIONALE DELLE RICERCHE - DANIELI TELEROBOT LABS S.R.L. - Eidgenössische Technische Hochschule Zürich - - - EUR 3 460 823,28 - - - Deictic Communication - A Multidisciplinary Training - - - EUR 3 460 823,28 - - - United Kingdom - Spain - Denmark - United Kingdom - Germany - Norway - Sweden - Germany - Italy - Italy - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - Deictic communication is fundamental to understanding communication in both typical and atypical populations, and forms the key connection between language and objects/locations in the world. It is therefore critical to - understanding human-human interaction, and human-system interaction in a range of technology applications – from mobile phones to cognitive robotics – and to the enhancement of clinical and educational interventions with typical and atypical - populations. This ETN will train the next generation of scientists in the full range of multidisciplinary and cross-sectorial methods necessary to make significant progress in understanding deictic communication, with direct synergies between basic - research and application. Training is structured around two interdisciplinary research themes – Understanding Deictic Communication and Deictic Communication in Application – both involving extensive and systematic co-supervision and collaboration - across sites with key interplay between academic and nonacademic beneficiaries and partners. In turn we expect that a range of applications will be enhanced with increased usability, with associated societal and economic benefit. The training of the - cohort of ESR fellows is based on innovative PhD training approaches, providing not only training in interdisciplinary methods, but also employing peer-assisted methods and the latest in educational innovation. This will produce a cohort of highly - skilled researchers who will be highly employable given the potential contribution they will make to future research and innovation in the public and private sectors. - - 2020-01-31, ongoing project - - - 2016-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - DCOMM - - - H2020-MSCA-ITN-2015 - - - 676063 - - - - - UNIVERSITEIT TWENTE - UNIVERSITEIT TWENTE - - - EUR 150 000 - - - Explore the potentialities of biostealth coatings for tissue engineering and reconstructive medicine - - - EUR 150 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - BioStealth production of implant coatings provides an exciting business opportunity. BioStealth offers unique advantages of societal and economic importance, such as public health and sick leave. - - - 2016-07-31, closed project - - - 2015-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2014 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Netherlands - - - BioStealth - - - ERC-2014-PoC - - - 641342 - - - - - UNIVERSITY OF PLYMOUTH - - - EUR 183 454,80 - - - Fundamental physics with intense laser fields - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - High-intensity lasers have the potential to offer groundbreaking insights into physics both within and beyond the Standard Model, as well as a wealth of applications in science, medicine, technology and industry. There is - therefore an international drive to explore fundamental physics in intense laser fields, in the regime where both relativistic and quantum effects are significant. - - 2018-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SF-QFT - - - H2020-MSCA-IF-2015 - - - 701676 - - - - - Fundació Institut d'Investigació Biomèdica de Bellvitge - UNIVERSITY COLLEGE LONDON - FORSCHUNGSVERBUND BERLIN EV - THE BABRAHAM INSTITUTE - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - CENTRE EUROPEEN DE RECHERCHE EN BIOLOGIE ET MEDECINE - FUNDACIO PRIVADA INSTITUT D'INVESTIGACIO ONCOLOGICA DE VALL-HEBRON - UNIVERSITA DEGLI STUDI DI TORINO - UNIVERSITAET BASEL - ARIVIS AG - - - EUR 3 896 334,72 - - - Deciphering PI3K biology in health and disease - - - EUR 3 896 334,72 - - - Spain - United Kingdom - Germany - United Kingdom - France - France - Spain - Italy - Switzerland - Germany - - - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The Phosphoinositide 3-kinase (PI3K) pathway is at the core of multiple fundamental biological processes controlling metabolism, protein synthesis, cell growth, survival, and migration. This inevitably leads to the involvement - of the PI3K signalling pathway in a number of different diseases, ranging from inflammation and diabetes to cancer, with PI3K pathway alterations present in almost 80% of human cancers. Therefore, PI3Ks have emerged as important targets for drug - discovery and, during 2014, the first PI3K inhibitor was approved by FDA in the US for the treatment of a lymphocytic leukaemia. Nonetheless, our understanding of PI3K-mediated signalling is still poor and only a fraction of the potential therapeutic - applications have been addressed so far, leaving a large amount of translational work unexplored. Europe features a set of top quality research institutions and pharmaceutical companies focused on PI3K studies but their activities have been so far - scattered. This proposal fills this gap by providing a multidisciplinary network (biochemistry, mouse studies, disease models, drug development, software development) and an unprecedented training opportunity from the bench to the bedside (from - pre-clinical discoveries to clinical trials), through cutting edge molecular biology, drug discovery and clinical trial organization. The proposal is aimed at training young investigators in deep understanding of the different PI3K isoforms in - distinct tissues and to translate this knowledge into a new generation of PI3K inhibitors, treatment modalities and into identify new uses for existing PI3K inhibitors. - - 2019-10-31, ongoing project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Spain - - - Phd - - - H2020-MSCA-ITN-2015 - - - 675392 - - - - - UNIVERSITEIT TWENTE - UNIVERSITEIT TWENTE - - - EUR 149 578,75 - - - Hypermethylated DNA detection using NanoGaps - - - EUR 149 578,75 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - HYMEDNA prepares commercialization of very sensitive point-of-care biosensors for early-stage cancer detection based on the electrical detection of hypermethylated DNA (hmDNA) inside nanogaps. - - 2016-09-30, closed project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2014 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Netherlands - - - HYMEDNA - - - ERC-2014-PoC - - - 665651 - - - - - CENTRO DE INVESTIGACION ECOLOGICA YAPLICACIONES FORESTALES CONSORCIO - - - EUR 170 121,60 - - - Remote sensing INdicators for DROught monitoring - - - EUR 170 121,60 - - - Spain - - - Research Organisations - - Droughts affect most parts of the world. According to the recent previsions of the Intergovernmental Panel on Climate Change1 (IPCC), more frequent and severe droughts are expected. This observation makes it a priority to - improve the existing methods of monitoring droughts and their impact on terrestrial ecosystems. Early warning systems need to be developed. Remote sensing (RS) technologies are well-placed to provide such monitoring. Thanks to RS, droughts can be - monitored at large scale and at short time resolution (e.g., daily). The proposed project “INDRO” will focus on the definition of new RS-based indicators able to monitor vegetation status and how it is responding to drought. For example, the RS - indicators implemented at the moment within the European Drought Observatory (EDO) early monitor system are not sensitive to rapid changes in plant photosynthesis since these indicators have no direct link to plant photosynthetic functioning. The - project will analyse the relationships between ecophysiological variables, light use activity (LUE) and existing RS indicators calculated with the data from several satellite sensors. This analysis will reveal which sensors, and which spatial and - temporal resolutions are best at quantifying drought. A new generation of RS indicators will be developed to give a better description of plant photosynthetic functioning in drought conditions. The project will map these new indicators for southern - Europe to identify the areas affected by drought. Overall, the creation of new RS drought indicators, and the better definition of drought events they bring, will help the development of ecological models and early warning systems, and underpin new - avenues for the improvement of national and international drought mitigation and adaptation strategies. - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - INDRO - - - H2020-MSCA-IF-2015 - - - 702717 - - - - - CHALMERS TEKNISKA HOEGSKOLA AB - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSITAET BASEL - AKADEMIA GORNICZO-HUTNICZA IM. STANISLAWA STASZICA W KRAKOWIE - THE HEBREW UNIVERSITY OF JERUSALEM - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - TECHNISCHE UNIVERSITAET DRESDEN - RUDER BOSKOVIC INSTITUTE - EIDGENOSSISCHE MATERIALPRUFUNGS- UND FORSCHUNGSANSTALT - - - EUR 4 193 147,25 - - - Reservoir Computing with Real-time Data for future IT - - - EUR 4 193 147,50 - - - Sweden - France - Switzerland - Poland - Israel - France - Germany - Croatia - Switzerland - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - - The aim of this proposal is to develop an intelligent biocompatible sensing device which detects complex behavioural changes in ion concentrations. The sensor will use wet NOMFETs, coated Si nanowires, self-conjugated - polymers, arrays of photocells, flow of lipids. The level of ions will be measured by monitoring changes in the response function of the system. The high sensitivity of the device will be achieved by ensuring a strong coupling between the environment - and the device. The key research challenges will be: accessing the feasibility of the idea to use reservoir computing for sensing complex environmental changes, identifying suitable integration strategies for the components, optimizing the sets of - input/output pairs (response functions) and the device components for enhanced sensitivity. - - 2018-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-1-2014 - FET-Open research projects - - - RIA - Research and Innovation action - - - Sweden - - - RECORD-IT - - - H2020-FETOPEN-2014-2015-RIA - - - 664786 - - - - - ARISTOTELIO PANEPISTIMIO THESSALONIKIS - ARISTOTELIO PANEPISTIMIO THESSALONIKIS - UNIVERSITAET BASEL - UNIVERSITAET HOHENHEIM - UNIVERSITAT WIEN - OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN - - - EUR 1 891 875 - - - Identifying the food cultures of ancient Europe: an interdisciplinary investigation of plant ingredients, culinary transformation and evolution through time - - - EUR 1 891 875 - - - Greece - Greece - Switzerland - Germany - Austria - Austria - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - The project seeks to explore culinary practice among early farming European communities, from the Aegean to Central Europe, spanning the Neolithic through to the Iron Age (7th-1st millennia BC). The project seeks to identify - the ‘food cultures’ of prehistoric Europe, and to reconstruct how cultivated and wild plant foods were transformed into dishes exploring their underlying cultural and environmental contexts and their evolution through time. The project will explore - how culinary identities were shaped through the selection of plant foods both in terms of ingredients as well as processing and cooking practices. Thus not only species and meals but also the equipment involved in plant food preparation will be - considered for the study area, linking the end product to the relevant technologies of transformation. Macroscopic and microscopic examination of the archaeological finds and experimental replication of various aspects of food preparation techniques - informed by ethnographic investigations will form the main analytical tools. The interdisciplinary and contextual examination of the archaeological record will provide a fresh insight into prehistoric cuisine in Europe, the transformation of nature - to culture through cooking. The project will revolutionise perceptions of prehistoric food preparation providing insights for the ‘longue durée’ of traditional plant foods constituting Europe’s intangible cultural heritage. - - 2021-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Greece - - - PLANTCULT - - - ERC-2015-CoG - - - 682529 - - - - - UNIVERSITEIT TWENTE - UNIVERSITEIT TWENTE - - - EUR 150 000 - - - On-Chip Cytometry Printed On Demand - - - EUR 150 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Cytometry (the characterisation and counting of cells) is essential to clinical diagnostics, biotechnology, food industry, water monitoring and many fields of research. Within the ERC Starting Grant, InstantCount, inkjet - printing methods have been developed, which allow us to fabricate cell counting chambers with on-chip sample preparation, simplifying cell counting procedures tremendously. By effectively eliminating all sample preparation steps and efficient usage - of reagents CyPod promises low-cost, simple, rapid cell counting, including mobile applications. The fabrication by inkjet printing enables us to offer tailor-made solutions. We expect that CyPod tests can replace expensive and complex instruments in - many existing cell counting applications, as well as open new markets, e.g. in agriculture and food industry. This project aims at evaluating and enhancing the competitiveness of CyPod cell counting technology by analysing the market, comparing CyPod - with potential competitors and adapting our concept to identified customers’ needs. A product demonstration for potential customers and partners will be prepared and the optimal business strategy will be selected for which a business plan will be - devised. - - 2017-08-31, closed project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2015 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Netherlands - - - CyPod - - - ERC-2015-PoC - - - 694045 - - - - - UNIVERSITY OF PLYMOUTH - - - EUR 183 454,80 - - - Sediment linkage between land, river and sea: evaluating impacts of historic mining on sediment quality in the coastal zone - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Monitoring datasets available to evaluate past mining impacts on catchment and coastal environmental quality are severely limited in temporal extent presenting a major hindrance to effective decision making for management of - legacy pollution to achieve the goals of the EU Water Framework Directive and Mining Waste Directive. The “Sediment linkage between land, river and sea: evaluating impacts of historic mining on sediment quality in the coastal zone” (SEDiLINK) - research project will develop an innovative sedimentological approach to overcome these important challenges and close this substantial knowledge gap. The SEDiLINK approach will bring together established techniques (e.g. Pb-210 geochronology) with - new approaches in evaluating riverine ecosystems (e.g. Pb isotope fingerprint) and deliver an integrated toolkit for evaluation of mine waste impacts. The extensive metal mining history of Tamar River Basin and coastal zone, southwest UK, offers an - ideal test-bed in which to develop the novel and powerful SEDiLINK approach for wider application in other EU contaminated fluvial and coastal ecosystems requiring longer term remediation legacy pollution. - - 2017-06-30, closed project | - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SEDiLINK - - - H2020-MSCA-IF-2014 - - - 658863 - - - - - UNIVERSITY OF PLYMOUTH - - - EUR 251 857,80 - - - Inclusive Education for an Inclusive Europe: Examining Social Interactions, Dynamics and Friendship Networks of Students in Mainstream Primary Schools - - - EUR 251 857,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The overarching research aim of this project is to examine the social interactions, dynamics and friendship networks of all students, with an emphasis on those identified as having special educational needs, in mainstream - primary schools. The IE2 project strives to understand how inclusive education is being implemented across three countries (US, UK, Cyprus) and contribute to the debate on how to create a more inclusive European society by providing rigorous research - evidence and recommendations. The project sets out to achieve three main objectives. First, to develop an innovative and interdisciplinary methodology to understand the social interactions, peer relationships and friendships with the combination of - advanced social network analysis and ethnographic methods. Second, to establish a social network analysis toolkit for schools to enable practitioners understand the social dynamics within their settings. Third, to develop a platform for visualizing - large datasets within social sciences and humanities. It is anticipated that the project will generate a significant impact on both the educational and social sciences and the researcher in terms of reaching a higher position of professional - maturity. This is a project that is innovative and interdisciplinary as it breaks the boundaries between social sciences and humanities and computational studies, mathematics and statistics. - - 2018-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - IE2 - - - H2020-MSCA-IF-2014 - - - 660607 - - - - - UNIVERSITA DEGLI STUDI DI PADOVA - TECHNISCHE UNIVERSITEIT EINDHOVEN - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - UNIVERSITEIT TWENTE - FREIE UNIVERSITAET BERLIN - WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER - - - EUR 2 321 096,40 - - - Multivalent Molecular Systems for Innovative Applications - - - EUR 2 321 096,40 - - - Italy - Netherlands - United Kingdom - United Kingdom - Netherlands - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This network brings together the major academic players active in Europe on the fundamentals and application of multivalency and cooperativity. The network is complemented by industrial partners ranging in scale from a small - spin-off to a large multinational. The main objective of this consortium is to raise a new generation of researchers able to develop complex chemical systems that harness cooperativity for enhanced functional properties. - - 2018-12-31, ongoing project | - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Italy - - - MULTI-APP - - - H2020-MSCA-ITN-2014 - - - 642793 - - - - - EUROPEAN SUSTAINABLE ENERGY INNOVATION ALLIANCE - ESEIA, VEREIN FUR FORDERUNG DER EUROPAIESCHEN INNOVATION FUR ERNEUERBARE ENERGIEN - BRP-POWERTRAIN GMBH & CO KG - ENERGIE AGENTUR STEIERMARK GEMEINNUTZIGE GMBH - TECHNISCHE UNIVERSITAET GRAZ - UNIVERSITE DE LIEGE - UNIVERSITY OF ZAGREB - FACULTY OF FOOD TECHNOLOGY AND BIOTECHNOLOGY - UZAG PBF - SVEUCILISTE U ZAGREBU, FAKULTET STROJARSTVA I BRODOGRADNJE - LAPPEENRANNAN TEKNILLINEN YLIOPISTO - INSTITUT POLYTECHNIQUE DE GRENOBLE - BERGISCHER ABFALLWIRTSCHAFTSVERBAND - UNIVERSITEIT TWENTE - Laboratorio Nacional de Energia e Geologia I.P. - TORRES & BELO SA - "ASOCIATIA ""GREEN ENERGY""" - - - EUR 1 377 000 - - - People for tHe eurOpean bioENergy mIX - - - EUR 1 377 000 - - - Austria - Austria - Austria - Austria - Belgium - Croatia - Croatia - Finland - France - Germany - Netherlands - Portugal - Portugal - Romania - - - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - - The development and adoption of renewable and sustainable forms of energy has become a major priority for Europe and is an important theme in H2020. Research into new, energy-related technologies to reduce Europe’s reliance on - non-renewable fossil fuels is a critical need, and requires more newly qualified people in areas such as renewable-energy infrastructure management, new energy materials and methods, as well as smart buildings and transport. Bio-energy is - particularly relevant to the Work Programme, because it is at the crossroads of several key European policies – from the Strategic Energy Technology Plan Roadmap on Education and Training (SET-Plan) to the European Bio-economy Strategy for European - Food Safety and Nutrition Policy. So far, technological development has concentrated on using crops and wood for fuel, energy and industrial products. These conventional bio-resources are, however, limited, and the use of nonconventional, currently - unused or under-utilised bio-resources provides the best possibility for the growth of the bioeconomy. However, European development in this priority field is failing to keep pace with demand due to a lack of qualified personnel, a lack of cohesion - and integration among stakeholders, and poorly developed links between professional training and the real needs of industry. Based on seven work packages the Phoenix RISE project will address these issues by exploiting the complementary expertise of - its partners and creating synergies between them through the targeted secondments of staff to advance research and innovation knowledge in bio-energy research. Phoenix is an international, interdisciplinary, cross-sectorial project, bringing together - a total of 16 partners: 14 from the EU (5 companies and 9 academic organisations) and two Third-Country academic partners to enhance its collective research excellence and create new, post-graduate-level research training in key disciplines that - support the provision of bio-energy. - - 2019-11-30, ongoing project - - - 2015-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Austria - - - Phoenix - - - H2020-MSCA-RISE-2015 - - - 690925 - - - - - UNIVERSIDAD COMPLUTENSE DE MADRID - - - EUR 239 191,20 - - - A new generation of AptaSensors - - - EUR 239 191,20 - - - Spain - - - Higher or Secondary Education Establishments - - The aim of this project is to design different next generation libraries of biosensors that will yield ready-to-go analytical tools against any target in unprecedented speed and high affinity. The project intends to focus on - aptamers, a new generation of recognition elements that will be integrated into bioelectronics devices. - - - 2019-05-31, ongoing project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Spain - - - APTASENS - - - H2020-MSCA-IF-2014 - - - 656687 - - - - - CESSDA AS - CHARLES BEAGRIE LIMITED - ETHNIKO KENTRO KOINONIKON EREVNON - TARKI ALAPITVANY - TARTU ULIKOOL - UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN - INSTITUTO DE CIENCIAS SOCIAIS - SVEUCILISTE U ZAGREBU FILOZOFSKI FAKULTET - INSTITUT EKONOMSKIH NAUKA - SOCIOLOGICKY USTAV SLOVENSKEJ AKADEMIE VIED - UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA - ASOCIATIA ARHIVA ROMANA DE DATE SOCIALE - - - EUR 2 498 187 - - - Strengthening and widening the European infrastructure for social science data archives. - - - EUR 2 498 187 - - - Norway - United Kingdom - Greece - Hungary - Estonia - Ireland - Portugal - Croatia - Serbia - Slovakia - Italy - Romania - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Other - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - - After CESSDA's successful launch we must now achieve full European coverage, and strength and sustainability for the widened network. - - - 2017-10-31, closed project - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-3-2015 - Individual implementation and operation of ESFRI projects - - - RIA - Research and Innovation action - - - Norway - - - CESSDA-SaW - - - H2020-INFRADEV-1-2015-1 - - - 674939 - - - - - HELSINGIN YLIOPISTO - - - EUR 191 325,60 - - - What is comparative legal history? Legal historiography and the revolt against formalism, 1930-60 - - - EUR 191 325,60 - - - Finland - - - Higher or Secondary Education Establishments - - What is comparative legal history? This research aims to show that to understand the rise of this field of inquiry we need first to clarify how historiography changes in time. To this purpose, the proposed research begins from two main ideas. - - 2019-09-20, ongoing project - - - 2017-09-21 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Finland - - - CLH - - - H2020-MSCA-IF-2016 - - - 753427 - - - - - UNIVERSITY OF PLYMOUTH - - - EUR 183 454,80 - - - Paleozoic Seafloor Spreading - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - It is now recognised that large oceanic detachment faults are fundamentally important along slow-spreading rate portions of the mid-ocean ridge system. These fault systems have been the target of numerous scientific - expeditions leading to a new paradigm of “detachment-mode” spreading. However, in the modern oceans this style of spreading can only be documented back to 10-12 Ma. To understand these systems in the deep geological past it is necessary to work on - ancient examples of detachment faults in ophiolites, slices of oceanic lithosphere that have been emplaced tectonically onto continental margins and which expose ocean floor structures in 3-D. Recent work in the Mirdita ophiolite of Albania has - demonstrated that detachment-mode spreading operated in the Jurassic period. This project will extend this record back to the Palaeozoic, by investigating a detachment system preserved in the Thetford Mines Ophiolite of Canada. An integrated - field-based structural and palaeomagnetic investigation will test the hypothesis that this example provides the oldest known analogue for modern oceanic detachment systems. Objectives are to: (i) systematically back-strip successive tectonic events - that have affected the ophiolite, in order to recover primary seafloor relationships; (ii) determine whether relative tectonic rotation has occurred across the detachment fault, a defining feature of modern examples; and (iii) quantify the role of - large- and small-scale faulting in accommodating displacement within the detachment system. The project will provide: (i) extensive training in field-based tectonic applications of palaeomagnetism, directly complementing the Fellow’s existing - expertise and experience in laboratory techniques, thereby allowing her to conduct future investigations in complex tectonic environments; and (ii) engagement with the international oceanic scientific community, opening future opportunities to move - into oceanic geodynamic research. - - 2017-09-03, closed project - - - 2015-09-04 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - PASS - - - H2020-MSCA-IF-2014 - - - 660362 - - - - - UNIVERSITY OF ESSEX - - - EUR 195 454,80 - - - French-English bilinguals' processing of morphosyntactic structures: the case of cross-linguistic transfer - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - One question central to both bilingual first language acquisition (2L1) and second language development (L2) research is to understand the mechanisms that lead to systematic interaction between the languages, i.e. - cross-linguistic influence (CLI). To-date, we know that bilinguals’ two languages are continuously co-activated to some extent at the lexicon and sentence level. Bilinguals need to map different syntactic forms, i.e. one or more for each language, - onto the same discourse function, which occasionally leads to the entrenchment of the non-targetlike form. Yet, little is known about how the age of acquisition (2L1 vs. L2) and language dominance (expressive abilities, language exposure) affect the - processing mechanisms governing this phenomenon. - - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - BilProcess - - - H2020-MSCA-IF-2016 - - - 752153 - - - - - UNIVERSITY OF PLYMOUTH - LIVERPOOL JOHN MOORES UNIVERSITY - NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA - - - EUR 517 500 - - - Partnership for Research in Geopolymer Concretes - - - EUR 517 500 - - - United Kingdom - United Kingdom - Greece - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Concrete, owing to its availability, easy preparation and fabrication, is the most popular construction material. However, the cement industry is facing unprecedented challenges caused by energy resources and CO2 emissions. - Despite the incremental improvements in process efficiency adopted by the cement industry in recent years, OPC production is still responsible for around 6% of all man-made global carbon emissions. The proposed project aims to develop green concretes - by using novel geopolymer materials as new binder and recycled concrete as part of the aggregates. The geopolymer is a type of amorphous alumina-silicate products. It can be synthesized by poly-condensation reaction of geopolymetric precursor and - alkali polysilicates, which are available in natural materials or from industrial by-products. Geopolymer materials represent an innovative technology that is generating considerable interest in the construction industry, particularly in light of the - ongoing emphasis on sustainability. However, although numerous geopolymer systems have been proposed, most are difficult to work with and require great care in their mixing process. Furthermore, the lack of long-term performance and durability data - is also a barrier to the acceptance and widespread commercial use of geopolymer concretes in the construction industry. The proposed research will cover not only the finding of novel geopolymers but also provide long-term performance and durability - data for geopolymer concretes used in different environments. The research outcome will have a great impact on our understanding of how geopolymer concretes perform in different environments and how their mechanical properties and performance can be - improved by using correct mixing processes. The research will also provide vital information on how to revolutionise the production of concrete materials and how to engineer concrete binders using different geopolymers to tailor the properties of the - resulting concrete. - - 2020-05-31, ongoing project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - United Kingdom - - - PRIGeoC - - - H2020-MSCA-RISE-2015 - - - 689857 - - - - - THE UNIVERSITY OF LIVERPOOL - - - EUR 183 454,80 - - - Iceland: Physical Anthropology of Colonization and Evolution - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Iceland was one of the last European countries to be settled, with the main period of migration taking place from the 9th to 10th centuries. After these initial migrations, the population of Iceland is thought to have been - largely genetically isolated until the 20th century. It has been suggested that the initial populations were of Scandinavian and Irish descent, with some scholars suggesting that individuals of Irish decent accompanied the Scandinavian Vikings to - Iceland as slaves. However, the accuracy of these suggestions is debated, making the genetic and cultural composition of the initial Icelandic population unclear. Therefore, there are a number of important questions regarding the settlement of - Iceland and the mobility of early Europeans that remain unanswered. Three of these questions will be the focus of this study: Who were the initial settlers of Iceland? Did the colonisation of Iceland involve elements of the Viking slave trade? How - did migration and subsequent isolation impact the biocultural diversity of the Icelandic human population? The proposed project will address these questions by investigating cranial shape with cutting-edge three-dimensional (3D) shape analysis - techniques. The project will include analyses of Icelandic archaeological populations and individuals deriving from the two proposed colonizing populations – i.e. early Scandinavian and Irish human remains. Cranial shape variation will be analysed to - identify relationships between the different populations and how Icelandic variation changed after settlement of the island. The findings of this project will significantly add to our understanding of early European migrations, as well as provide new - insight into how migration to a new environment, possible adoption of a new diet, and exposure to a new gene pool influenced modern Icelandic population diversity. - - 2019-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - IPACE - - - H2020-MSCA-IF-2016 - - - 748200 - - - - - UNIVERSITAET BASEL - - - EUR 175 419,60 - - - Development of an artificial alkane monooxygenase: A leap in bioinspired oxidation catalysis - - - EUR 175 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - The oxygenation of inert C-H bonds is a highly challenging reaction that has an enormous untapped potential for the European chemical industry. Indeed, it offers attractive means to upgrade cheap hydrocarbons into high - value-added products. Nature relies on iron-based enzymes and oxygen to perform such transformations. In a biomimetic spirit, catalytic alkane hydroxylation is best achieved using iron-based catalysts and H2O2 as oxidant. Compared to natural enzymes, - however, such systems display modest performance. In the TAML-ArM project, we aim to the development of a novel approach that consists of creating an artificial alkane monooxygenase by introducing a highly active iron complex within a protein - scaffold. This strategy, pioneered in the Ward group, has ample precedent for less challenging reactions, and it potentially represents a significant step forward in bioinspired hydroxylation chemistry. To achieve this goal artificial metalloenzymes - merge homogeneous- and enzymatic catalysis, two traditionally complementary strategies. We envision that this approach will: i) improve the catalytic activity by protecting the highly reactive Fe=O-moiety by shielding it from undesirable - side-reactions and ii) provide novel selectivities, owing to second coordination sphere interactions between the protein and the substrate. Thanks to this innovative catalytic approach, we will develop a paradigm shifting technology for the selective - hydroxylation of hydrocarbons: the reactions will be performed in water at room temperature using benign H2O2 as oxidant. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - TAML-ArM - - - H2020-MSCA-IF-2016 - - - 747125 - - - - - UNIVERSITAET BASEL - - - EUR 175 419,60 - - - Emitter-mediated Photon-Phonon InteraCtion - - - EUR 175 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - This action, “Emitter-mediated Photon-Phonon InteraCtion” (EPPIC), will contribute to the research areas of quantum computing and quantum sensors. These are key areas of the quantum technologies flagship initiative, which has - the goal of establishing Europe as a leader in the second quantum revolution and its future industrial exploitation. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - EPPIC - - - H2020-MSCA-IF-2016 - - - 747866 - - - - - THE UNIVERSITY OF EXETER - - - EUR 195 454,80 - - - Sperm telomere length as a mediator of paternal effects - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Despite having long been overlooked, paternal effects (influence of fathers on offspring traits via mechanisms other than the transmission of alleles) are now recognized as affecting a broad range of phenotypic traits in the - next generation. There is, for example, increasing evidence for transgenerational effects of paternal stress levels with consequences on offspring health. In most cases, the proximate mechanism mediating these paternal effects on offspring remains - unknown. - - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - United Kingdom - - - TELOSPERM - - - H2020-MSCA-IF-2016 - - - 746669 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 183 454,80 - - - Pasteur's Empire - French Expertise, Colonialism, and Transnational Science - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - This project investigates how bacteriologists at the Pasteur Institute reimagined the French empire as a biotechnological space of experimentation in the early twentieth century, and conversely, how medical technologies - developed in French colonies in Indochina, West Africa and Tunisia were enrolled to both shore up and challenge colonial power. - - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - PE-FECATS - - - H2020-MSCA-IF-2016 - - - 747591 - - - - - HELSINGIN YLIOPISTO - - - EUR 191 325,60 - - - Speciation in ants: Unraveling the genetic, epigenetic and molecular basis of speciation using wood ants - - - EUR 191 325,60 - - - Finland - - - Higher or Secondary Education Establishments - - The enormous amount of diversity that surrounds us raises one of the key questions in evolutionary biology: How do new species originate? Speciation depends on the evolution of reproductive isolation but, with few exceptions, - the genes underlying reproductive isolation and their modes of action are unknown. The novelty of this project lies in testing if, in addition to mutations in genes, epigenetics and gene expression are mechanisms that contribute to the process of - speciation. For these aims I will use wood ants and their hybrids combining large-scale data sets on genomes, gene expression and genome-wide methylation. These approaches will be complemented with protein modeling of candidate genes resulting in a - multidisciplinary project. Further aims are to develop an outreach programme on evolution for high schools and in collaboration with the Finnish Environment Institute to investigate the role of hybrids in forest ecosystems. Together these objectives - yield a project that has high scientific standing and societal importance. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Finland - - - SpecIAnt - - - H2020-MSCA-IF-2016 - - - 750015 - - - - - UNIVERSITAET BASEL - - - EUR 175 419,60 - - - Fate of mammary stem cells during tumorigenesis and clinical implications - - - EUR 175 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - One of the most challenging questions in breast cancer biology is to elucidate the origin of tumor heterogeneity and its contribution to therapy failure. Accumulating evidence suggests that the cell-of-origin, the cell that - acquires the first oncogenic event, may define the molecular portrait of the resulting tumor. The fate of mammary Stem Cells (MSC) upon oncogenic perturbation has been poorly explored. Moreover, the Phosphoinositide 3-kinase (PI3K) pathway regulates - proliferation/differentiation of MSC and is found hyperactive in breast cancer cells, for example through mutations in PIK3CA, the gene coding for its catalytic subunit. I hypothesize that expression of PIK3CA mutations will perturb mammary tissue - homeostasis, initiate mammary cancer and trigger formation of stem-like cancer cells. Using state-of-the-art in situ genetic lineage tracing, I will determine the fate of MSC (identified recently as Procr+ cells) after conditional expression of - PIK3CA hotspot mutations (H1047R, E545K). I will also characterize early molecular events responsible for promotion of transformation (Aim 1). When tumors develop, I will determine tumor phenotype and eventual progression to metastasis (Aim 2). - Consequently, this study will generate a new mouse model of breast cancer that will be useful for preclinical studies. A panel of PI3K inhibitors is currently under Clinical investigation and clinical reports have shown that the combination of - standard chemotherapy with PI3K inhibitors reduces tumor growth but drug-resistance often occurs. To identify resistance mechanisms to PI3K inhibitors, I will generate in vivo models of drug-resistance (Aim 3). My studies will use both hypothesis - driven and unbiased approaches, they should: 1. better elucidate transformation of MSC and the resulting tumor heterogeneity, 2. pinpoint novel targets/biomarkers. Ultimately this knew knowledge should result in better therapies for patients. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - MSCFate - - - H2020-MSCA-IF-2016 - - - 750812 - - - - - DANMARKS TEKNISKE UNIVERSITET - DANMARKS TEKNISKE UNIVERSITET - - - EUR 149 951 - - - CodeSphere - Discovering Therapeutic Nanoparticles by Molecular Encoding - - - EUR 149 951 - - - Denmark - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - There is currently no high-throughput method to efficiently identify and optimize nanoparticle delivery of therapeutic relevant cargo such as drugs or mRNA before progression through costly clinical development. This is in - stark contrast to the situation for small molecules and antibodies, where screening technologies such as high-throughput small molecule screening and phage display in the last decades have proven very successful to aid and drive drug discovery and - development. - - 2019-02-28, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Denmark - - - CodeSphere - - - ERC-2017-PoC - - - 767882 - - - - - FUNDACIO INSTITUT DE CIENCIES FOTONIQUES - FUNDACIO INSTITUT DE CIENCIES FOTONIQUES - - - EUR 150 000 - - - Platform for label-free quantitative detection of single proteins and extracellular vesicles - - - EUR 150 000 - - - Spain - Spain - - - Research Organisations - Research Organisations - - The main objective of the IBIS project is to develop an ultrasensitive, compact and low cost platform for the label-free quantitative detection of single proteins, and specifically the characterisation of nanometric - extracellular vesicles. We will develop a prototype to transfer our novel detection scheme from the laboratory to the clinical environment and, based on user-feedback, develop a commercialization plan. - - - 2019-02-28, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Spain - - - IBIS - - - ERC-2016-PoC - - - 755196 - - - - - QUEEN MARY UNIVERSITY OF LONDON - QUEEN MARY UNIVERSITY OF LONDON - - - EUR 149 728 - - - Biomimetic mineralization for enamel regeneration - - - EUR 149 728 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Dental enamel has a unique chemical composition and a remarkable well-defined hierarchical structure, which together are responsible for its outstanding properties and critical functionality. Once lost, this tissue cannot be - regenerated and is directly involved in a variety of dental problems that affect a large percentage of the world population. This ERC PoC project (ENAMULATE) aims to develop the world’s first human dental enamel regeneration material capable of - recreating natural enamel in structure and chemical composition; treating dental defects; and replacing restorative materials currently used in dental clinics. The project builds on findings from the ERC Starting Grant STROFUNSCAFF on the development - of an elastin-like protein (ELP) self-assembling process capable of triggering and guiding the hierarchical growth of hydroxyapatite as biocompatible, flexible, and robust coatings in vitro over large uneven areas and directly on human enamel and - exposed dentinal tubules. ENAMULATE will optimize the crosslinking mechanism to facilitate its clinical use in the operating room, confirm its efficiency in vitro, and validate its performance in an established animal model. The project will also - focus on setting up and moving forward a path towards commercialization by consolidating the intellectual property, investigating the industrial viability, and identifying potential markets. - - 2019-04-30, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - ENAMULATE - - - ERC-2016-PoC - - - 755191 - - - - - STICHTING KATHOLIEKE UNIVERSITEIT BRABANT - STICHTING KATHOLIEKE UNIVERSITEIT BRABANT - - - EUR 1 499 046 - - - Discriminative preferences and fairness ideals in diverse societies: An ‘experimental economics’ approach - - - EUR 1 499 046 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In economics, a distinction is made between statistical and taste-based discrimination (henceforth, TBD). Statistical discrimination refers to discrimination in a context with strategic uncertainty. Someone who is uncertain - about the future behaviour of a person with a different ethnicity may rely on information about the different ethnic group to which this person belongs to form beliefs about the behaviour of that person. This may lead to discrimination. TBD refers to - discrimination in a context without strategic uncertainty. It implies suffering a disutility when interacting with ‘different’ others. This project systematically studies TBD in ethnically diverse societies. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - DIVERSE-EXPECON - - - ERC-2016-COG - - - 724231 - - - - - UNIVERSITY OF LEEDS - - - EUR 97 727,40 - - - The effects of financial capital accumulation on employment and wealth distribution - - - EUR 97 727,40 - - - United Kingdom - - - Higher or Secondary Education Establishments - - This project will analyse the relationship between the logic of financial accumulation and declining working conditions as well as the widening breach in social inequality affecting large segments of the European population. - Studies carried out to date have failed to provide a systematic explanation for the relationship between financialisation, employment and wealth distribution. This project will contribute to filling this knowledge gap in the comparative cases of - Spain and the UK, two different poles in terms of Eurozone economies. - - 2018-07-02, ongoing project - - - 2017-07-03 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - FUSION - - - H2020-MSCA-IF-2016 - - - 746622 - - - - - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - - - EUR 2 500 000 - - - Additive Micro-Manufacturing for Plastic Micro-flectro-Mechanical-Systems - - - EUR 2 500 000 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The manufacturing of silicon-based MEMS today is well advanced because the micro-electro-mechanical devices for automotive, domestic, health-care and consumer electronics can be fabricated with methods from IC industry. - Polymer-based MEMS have a great potential for flexible electronics and biomedical applications, but to date, the techniques to engineer functional polymers into 3D microsystems are still at their beginning because a coherent fabrication platform with - the right tools and processes does not yet exist. The field could tremendously benefit from a coordinated effort in materials and manufacturing, in particular with a focus on biocompatible plastic materials for biomedical applications. Additive - manufacturing such as 3D printing and associated processing such as sintering has already started to transform traditional industry, but is not scalable much below a micrometer because the thermal processing is done in bulk or by lasers on surfaces. - MEMS 4.0, in analogy with the industry 4.0 concept, aims to perform concerted research in additive manufacturing at the micro/nanoscale and associated key techniques. Using my expertise in MEMS and Nanotechnology, MEMS 4.0 will push the frontiers in - new materials and new processing for MEMS by setting a focus on stencilling, printing, self-assembly and local thermal processing. This coherent processing framework will permit the use of delicate, soft, polymer materials to engineer the next - generations of plastic MEMS. We are primarily targeting biodegradable implantable MEMS and permanently implantable glassy carbon MEMS. They are the most challenging to fabricate, but if successful, they also have an enormous impact for future - wearables and implantables. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Switzerland - - - MEMS 4.0 - - - ERC-2016-ADG - - - 742685 - - - - - UNIVERSITEIT TWENTE - UNIVERSITEIT TWENTE - - - EUR 2 937 500 - - - Diffusive Droplet Dynamics in multicomponent fluid systems - - - EUR 2 937 500 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Liquid-liquid extraction - the transfer of a solute from one solvent to another - is a core process in chemical technology and analysis. The current challenge is to miniaturise the analyte extraction process and to optimize - the extraction recovery and preconcentration factor. Lacking a priori calculations, this is now often done by trial-and-error. However, to control and optimize the extraction processes, it is crucial to quantitatively understand the diffusive droplet - dynamics in multicomponent fluid systems. This is essential and urgently needed not only for modern liquid-liquid extraction processes for diagnostics & microanalysis, for droplet microfluidics, or in the paint & coating industry, but on - larger scales also in remediation industry, in chemical technology, or in food processing. These applications of droplets governed by diffusion include cases of immersed droplets in the bulk & on a surface, single & multicomponent droplets - & solvents, and cases with high droplet number density. In spite of their relevance, multiphase & multicomponent fluid systems with relevant diffusive droplet dynamics are poorly understood. - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Netherlands - - - DDD - - - ERC-2016-ADG - - - 740479 - - - - - UNIVERSITEIT TWENTE - UNIVERSITEIT TWENTE - - - EUR 150 000 - - - Explore the potentialities of living implants for medical devices - - - EUR 150 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - IMPLANTaLive coating technology provides an exciting business opportunity. IMPLANTaLive offers unique advantages of societal and economic importance such as public health and sick leave. - - - 2018-09-30, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Netherlands - - - IMPLANTaLive - - - ERC-2016-PoC - - - 737637 - - - - - UNIVERSITE DU LUXEMBOURG - UNIVERSITE DU LUXEMBOURG - KUNGLIGA TEKNISKA HOEGSKOLAN - - - EUR 2 499 595 - - - Actively Enhanced Cognition based Framework for Design of Complex Systems - - - EUR 2 499 595 - - - Luxembourg - Luxembourg - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Parameterized mathematical models have been central to the understanding and design of communication, networking, and radar systems. However, they often lack the ability to model intricate interactions innate in complex - systems. On the other hand, data-driven approaches do not need explicit mathematical models for data generation and have a wider applicability at the cost of flexibility. These approaches need labelled data, representing all the facets of the system - interaction with the environment. With the aforementioned systems becoming increasingly complex with intricate interactions and operating in dynamic environments, the number of system configurations can be rather large leading to paucity of labelled - data. Thus there are emerging networks of systems of critical importance whose cognition is not effectively covered by traditional approaches. AGNOSTIC uses the process of exploration through system probing and exploitation of observed data in an - iterative manner drawing upon traditional model-based approaches and data-driven discriminative learning to enhance functionality, performance, and robustness through the notion of active cognition. AGNOSTIC clearly departs from a passive - assimilation of data and aims to formalize the exploitation/exploration framework in dynamic environments. The development of this framework in three applications areas is central to AGNOSTIC. The project aims to provide active cognition in radar to - learn the environment and other active systems to ensure situational awareness and coexistence; to apply active probing in radio access networks to infer network behaviour towards spectrum sharing and self-configuration; and to learn and adapt to - user demand for content distribution in caching networks, drastically improving network efficiency. Although these cognitive systems interact with the environment in very different ways, sufficient abstraction allows cross-fertilization of insights - and approaches motivating their joint treatment. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Luxembourg - - - AGNOSTIC - - - ERC-2016-ADG - - - 742648 - - - - - UNIVERSITEIT TWENTE - UNIVERSITEIT TWENTE - - - EUR 2 000 000 - - - Vascular Tree Formation in Multi-Structural Tissue Engineering - - - EUR 2 000 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Engineered tissues offer a great promise to the field of medicine as an alternative for donor tissues, for which the supply is not meeting the demands. However, the clinical application of engineered tissues is hampered. The - integration of engineered tissues after implantation is limited due to the lack of a vascular network. Currently, strategies to include vascular networks rely on the spontaneous organization of vascular cells, or on the patterning of these cells. - However, this results in either vascular networks that are not organized, or networks that lose their initial organization fast. This project will use a unique and novel approach to control vascular development and will therefore result in a vascular - network with a controllable long-term organization. By allowing for anastomosis, and increasing nutrient delivery, this project will tackle an essential problem and will greatly enhance the clinical applicability of engineered tissues. - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - VascArbor - - - ERC-2016-COG - - - 724469 - - - - - UNIVERSITEIT TWENTE - UNIVERSITEIT TWENTE - - - EUR 2 500 000 - - - Chemical Reaction Engineering by Additive Manufacturing of Mesoscale MetaMaterials - - - EUR 2 500 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - "The management of mesoscale dynamics is the missing link in gaining complete control over chemical processes like heterogeneous catalysis. The ability to accurately position nanoscale active elements in cellular mesoscale (nm - to µm-range) structures with high symmetrical order is instrumental in streamlining vital molecular or energetic paths. 3D periodicity in the structure that supports active or adsorption sites minimizes spatial variations in mass transport, whereas - mesoscale control of the location of these sites gives a route to tuning activity and functionality. The introduction of mesoscale metamaterials expands the on-going trend in chemistry, of more and more dimensionally refined structured elements, a so - to speak ""Moore's law in Process Intensification"". The roadmap to higher process efficiency dictates a next, disruptive step in mastering manufacturing control at smaller dimensions. The proposed disruptive technology to realize the required - mesoscale features is Additive Manufacturing, which is the only method offering the desired freedom in shape, symmetry and composition. More specifically, this project explores electrospinning methods with precise intra-wire control of the position - of active sites and accurately tuneable 3D inter-wire distances. This is seen as the ideal technique to reach the mesoscale material target, as the method is scalable to practical device volumes. The main ingredients of the novel technology are - microfluidic networks to line up nanoparticles, before electrospinning them with integrated micromachined nozzles, and depositing them accurately in the form of 3D nanowire networks, using integrated circuit collector electrodes. Flow-through, - cellular materials which are highly homogeneous in size and composition, or with intentionally embedded gradients, having features designed at the mesoscale, will be investigated for applications in the fields of heterogeneous catalysis and solar - energy capture and conversion." - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Netherlands - - - CREAM4 - - - ERC-2016-ADG - - - 742004 - - - - - LIVERPOOL JOHN MOORES UNIVERSITY - AALTO-KORKEAKOULUSAATIO - INSTITUTO SUPERIOR TECNICO - GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER - UNIVERSITY OF PLYMOUTH - MAHIDOL UNIVERSITY - UNIVERSITI KEBANGSAAN MALAYSIA - UNIVERSITI TEKNOLOGI MALAYSIA - Wuhan University of Technology - - - EUR 1 282 500 - - - REliability and Safety Engineering and Technology for large maritime engineering systems - - - EUR 1 417 500 - - - United Kingdom - Finland - Portugal - Germany - United Kingdom - Thailand - Malaysia - Malaysia - China - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Failure of large complex engineering systems often leads to catastrophic consequences. Their efficient and safe design and operation will avoid or reduce malfunctions, failures and accidents, which would have a significant - impact on the daily life of the public in terms of service and product delivery, business interruption, economic losses, human injuries/fatalities, and property and environmental damage. - - - 2021-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - United Kingdom - - - RESET - - - H2020-MSCA-RISE-2016 - - - 730888 - - - - - UNIVERSITEIT TWENTE - UNIVERSITEIT TWENTE - - - EUR 1 498 613,75 - - - Processing Citizenship: Digital registration of migrants as co-production of citizens, territory and Europe - - - EUR 1 498 613,75 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Intensifying migration waves are changing EU policies―with Hotspots being set up in frontline countries―but also the way knowledge about migrants, institutions and territory is created. Information systems are key enablers of - this knowledge. They materialize legislative, political, administrative dynamics in which citizenship, state and territory are co-produced. - - 2022-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - ProcessCitizenship - - - ERC-2016-STG - - - 714463 - - - - - UNIVERSITA CA' FOSCARI VENEZIA - UNIVERSITA CA' FOSCARI VENEZIA - - - EUR 1 999 976 - - - Institutions and Metaphysics of Cosmology in the Epistemic Networks of Seventeenth-Century Europe - - - EUR 1 999 976 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The focus of this project is the competing confessional discourses on cosmology of the seventeenth century, an epoch in which religious conflicts originated opposing ‘epistemic cultures’, which were embodied in scholarly - institutions and networks such as the Protestant web of northern European universities or the global web of Jesuit colleges. - - 2022-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Italy - - - EarlyModernCosmology - - - ERC-2016-COG - - - 725883 - - - - - UNIVERSITAET BASEL - UNIVERSITAET BASEL - - - EUR 1 999 941 - - - Hydrogen isotopes in plant-derived organic compounds as new tool to identify changes in the carbon metabolism of plants and ecosystems during the anthropocene - - - EUR 1 999 941 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - HYDROCARB is motivated by the enormous potential that stable hydrogen isotope ratios (δ2H values) in plant compounds have as hydrological proxy, but in particular as new proxy for the carbon metabolism in plants. Current - conceptual models suggest that δ2H values in plant organic compounds are composed of (i) hydrological and (ii) metabolic signals. The hydrological information that is contained in δ2H values of plant material is now well understood and is often - applied in (paleo-) hydrological research. In contrast, the metabolic information that is contained in plant δ2H values is mostly unknown. Intriguing recent research suggests, however, that metabolic signals in the δ2H values of plant organic - compounds reflect the balance of autotrophic and heterotrophic processes in plants. This suggests that exciting and previously unknown opportunities exist to exploit δ2H values in plant compounds for information on the carbohydrate metabolism of - plants, which would be relevant for a broad range of biological and biogeochemical disciplines. - - 2022-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Switzerland - - - HYDROCARB - - - ERC-2016-COG - - - 724750 - - - - - UNIVERSITAET BASEL - UNIVERSITAET BASEL - - - EUR 1 466 916 - - - Molecular Mechanical Adhesives - - - EUR 1 466 916 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Protein-based hydrogels are commonly used as adhesives and sealants in surgical settings. Fibrin gels, for example, are biocompatible, however their use is hampered by poor mechanical properties. Previous attempts to improve - fibrin gel mechanics relied on interpenetrating networks in combination with PEO, collagen and other polymers, however, only modest improvements were observed. The important challenge lies in understanding how molecular design principles can - influence gel mechanics on the macroscale. - - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Switzerland - - - MMA - - - ERC-2016-STG - - - 715207 - - - - - UNIVERSITEIT TWENTE - UNIVERSITEIT TWENTE - - - EUR 150 000 - - - BioREAD; a Continuous Barrier Quality Monitoring System for Organs-on-Chip - - - EUR 150 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Organs-on-chip are expected to play a crucial role in the pharmaceutical industry for drug development and study of organs and diseases. We propose the development of an electrical detector that enables simple, versatile and - continuous quality monitoring of these devices and is essential for commercialization. Combined with recent advances in stem cell technology, Organ-on-Chips can be used to do drug screening on an individual level. Therefore it can serve as instrument - for personalized medicine, by determining the effectiveness of selected compounds, as well as possible side-effects to determine safe drug doses on a person-specific level. Moreover, Organs-on-Chip will greatly contribute to a further reduction in - the need for animal testing. Besides the pharmaceutical industry, Organs-on-Chip hold great promise for the food and cosmetics industry to test the safety of products. - - 2018-06-30, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Netherlands - - - BioREAD - - - ERC-2016-PoC - - - 727641 - - - - - UNIVERSITA DEGLI STUDI DI CASSINO E DEL LAZIO MERIDIONALE - STICHTING IHE DELFT - TTY-SAATIO - UNIVERSITE PARIS-EST - - - EUR 3 918 950,64 - - - Advanced Biological Waste-to-Energy Technologies - - - EUR 3 918 950,64 - - - Italy - Netherlands - Finland - France - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The Advanced Biological Waste-to-Energy Technologies (ABWET) EJD provides education and research at PhD level on environmental technologies that convert waste materials into bioenergy, training doctoral candidates to think - globally and work in multidisciplinary research teams. This makes ABWET alumni attractive for European universities and industry, able to contribute to solving the global challenges of waste management, energy scarcity and sustainable development. - - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-EJD - Marie Skłodowska-Curie Innovative Training Networks (ITN-EJD) - - - MSCA-ITN-EJD - European Joint Doctorates - - - Italy - - - ABWET - - - H2020-MSCA-ITN-2014 - - - 643071 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - - - EUR 211 825,20 - - - Advancing Rechargeable-Batteries Through In Situ Techniques - - - EUR 211 825,20 - - - United Kingdom - United States - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Li-ion batteries (LIBs) have enabled the portable device revolution of the last two decades, and have undoubtedly had a dramatic societal impact, with rechargeable electronic devices now ubiquitous. The light Li-containing - electrodes, and high working cell voltages (typically >3.5 V) make LIBs the most practical solution for many portable applications. However, when significantly larger storage capacity is demanded, such as in transportation or grid-based energy - storage, the limited availability, and consequently elevated cost, of Li becomes prohibitive. This research project will investigate alternative battery technologies that use more earth-abundant ions for charge transport, namely Mg, to enable the - next generation of energy storage devices. The atomic-scale mechanisms of Mg-ion insertion/extraction at electrode-electrolyte interfaces and how these interfaces evolve during charging/discharging will be investigated. Complementary in situ - techniques will be used to investigate the evolution of electrode structure and chemical state using carefully designed model electrodes. The study of scaled-up electrodes integrated into complete batteries will extend this understanding to more - realistic battery cycling conditions. This will provide important insights to help overcome the limitations of the materials currently used in Mg-ion batteries (MIBs). The ground-breaking nature of this proposal lies in the level of fundamental - understanding we aspire to achieve based on in situ metrology. We thereby envision the rational design and optimisation of the next generation of rechargeable batteries, guided by more than just the existing empirical approach. - - 2017-12-31, closed project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - ARTIST - - - H2020-MSCA-IF-2014 - - - 656870 - - - - - UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSITAET HAMBURG - BAYERISCHE JULIUS-MAXIMILIANS UNIVERSITAT WURZBURG - TECHNISCHE UNIVERSITEIT EINDHOVEN - SINGLE QUANTUM BV - UNIVERSITY COLLEGE LONDON - THE UNIVERSITY OF SHEFFIELD - TOSHIBA RESEARCH EUROPE LIMITED - UNIVERSITAET BASEL - ATTOCUBE SYSTEMS AG - - - EUR 3 900 365,28 - - - Novel Quantum Emitters monolithically grown on Si, Ge and III-V substrates - - - EUR 3 900 365,28 - - - Italy - France - Germany - Germany - Netherlands - Netherlands - United Kingdom - United Kingdom - United Kingdom - Switzerland - Germany - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - We propose to forge a partnership between the leading European groups working on the next generation of solid state quantum emitters based on novel growth methods such as Droplet Epitaxy. Future, practical Nano-photonics and - Quantum Circuits applications demand semiconductor quantum dots that can be grown on substrates with different lattice parameters (Si, Ge, GaAs), different substrate orientations (such as (001) and (111)) and tuneable optical, electrical and spin - properties. All these requirements are met by high quality quantum dots grown with Droplet based Epitaxy techniques, circumventing the limitations of currently available systems based on strain-driven dot self-assembly. This vast novel research area - at the crossroads of photonics, material science, quantum physics and nano-scale device fabrication will allow delivering top level multidisciplinary training to 15 early stage researcher (ESRs). The successful training of the ESRs by leading - academic and 3 full industrial partners will be crucial for achieving the headline goals of this first ever consortium on droplet dot devices: (1) Entangled light emitting diodes with droplet dots grown on (111) substrates (2) Electrically triggered, - droplet dot based single photon sources on Si/Ge substrates (3) Strain tuning in droplet dots without wetting layer: photon polarization and single spin control (4) Droplet Dot based single photon sources for non- classical light storage devices - based on hybrid quantum systems (dots & laser-cooled atoms). The training and research progress will be discussed and monitored during the 4 project meetings, 3 summer schools and the final international conference on Droplet Dot Devices, all of - which are open to the whole scientific community. We expect this network, based on the solid collaboration between growth groups, microscopists, quantum optics experimentalists and theorists to explore the full potential of this emerging technology. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Italy - - - 4PHOTON - - - H2020-MSCA-ITN-2016 - - - 721394 - - - - - UNIVERSITEIT TWENTE - UNIVERSITEIT TWENTE - - - EUR 1 500 000 - - - Sustainable and Advanced Membranes By Aqueous Phase Separation - - - EUR 1 500 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Membranes play a critical role in the production of safe drinking water and in the treatment of human waste streams. However, membranes themselves are nearly always produced using costly, harmful and environmentally unfriendly - aprotic solvents such as N-methyl-pyrrolidone (NMP), dimethylformamide (DMF), or dimethylacetamide (DMAC). This proposal describes a highly novel approach allowing the production of the next generation of advanced membranes without the need to use - any organic solvents. Here we make use of so-called responsive polymers that can switch under aqueous conditions from a hydrophilic to a hydrophobic state by a simple change of, for example, pH. In the hydrophilic state, water dissolves the polymers - and the so obtained solution can be cast as a thin film. Sudden immersion in a bath at a pH where the polymer becomes hydrophobic, leads to very sudden phase separation whereby the polymer coagulates into a porous film, a membrane. Control over the - kinetics of this aqueous phase separation process allows for the fabrication of a large variety of porous structures. Furthermore, this process also works for two oppositely charged polymers, where polyelectrolyte complexation is used to induce phase - separation. Crosslinking will be a natural way to guarantee membrane stability but can also be used to further modify/improve membranes. The very nature of this aqueous phase separation process is such that membrane additives that are typically - associated with advanced membranes (responsive polymers, enzymes, polyzwitterions, metallic nanoparticles) can readily be incorporated. As such, aqueous phase separation not only allows solvent free membrane production, it also provides a very simple - and versatile route for the production of membranes with advanced properties. Finally, the porous structures and novel materials developed within this project could be directly useful for other applications, ranging from adsorption processes and - coatings to biomedical materials. - - 2021-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - SAMBA - - - ERC-2016-STG - - - 714744 - - - - - UNIVERSITY OF PLYMOUTH - DANMARKS TEKNISKE UNIVERSITET - NORDIC BIOSCIENCE COMPOUND DEVELOPMENT A/S - ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI - PROGNOMICS LTD - SWANSEA UNIVERSITY - UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA - CENTRO DE INVESTIGACION BIOMEDICA EN RED ENFERMEDADES NEURODEGENERATIVAS - UNIVERSITATSMEDIZIN ROSTOCK - ADVANCED MEDICAL PROJECTS SOCIEDAD LIMITADA - - - EUR 3 465 749,52 - - - Blood Biomarker-based Diagnostic Tools for Early Stage Alzheimer’s Disease - - - EUR 3 465 749,52 - - - United Kingdom - Denmark - Denmark - Italy - United Kingdom - United Kingdom - Italy - Spain - Germany - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Alzheimer’s disease (AD) affects more than 7 million people in Europe and this figure is expected to double every 20 years. Despite intensive efforts, no disease-modifying treatments or preventive strategies are available. The - lack of specific, sensitive and minimally invasive diagnostics to identify people with early-stage AD to be included in clinical drug intervention trials is among the main reasons for many notable trial failures. The main challenges in developing the - required diagnostics are identification of AD biomarkers and development of their detection techniques. The complex and interdisciplinary nature of the research underlines the need for innovative training of a new generation of researchers in the - field. BBDiag responds to such a need and establishes a much-needed ETN for blood based early-AD diagnostics to address these challenges. It brings together leading academic and industrial experts from five major consortia in Europe and uses their - synergies to build a triple-i research & training platform with the required multidisciplinary expertise and cutting-edge technologies. BBDiag Fellows will be trained under the Vitae Researcher Development Framework innovatively combined with the - BBDiag platform for gaining interdisciplinary scientific and transferable skills as well as personal quality, creative thinking and business mind-set. The ETN has a highly innovative research programme for the discovery of AD biomarkers, development - of novel biosensing techniques and point of care tools, and for technological exploitation of the diagnostics. These advances will strongly support improved care provision and development of disease-modifying treatments and preventive strategies for - AD patients. More importantly, BBDiag will deliver its first generation of 13 highly-skilled, creative and entrepreneurial Fellows, setting them on a path to successful careers in academia or industry to ensure that the medical and societal - challenges imposed by AD are met. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - BBDiag - - - H2020-MSCA-ITN-2016 - - - 721281 - - - - - UNIVERSITY OF STRATHCLYDE - INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE - CENTRO ITALIANO RICERCHE AEROSPAZIALI SCPA - ESTECO SPA - UNIVERSITY OF DURHAM - INSTITUT JOZEF STEFAN - POLITECNICO DI MILANO - UNIVERSITEIT GENT - DEUTSCHES ZENTRUM FUER LUFT - UND RAUMFAHRT EV - TECHNISCHE HOCHSCHULE KOLN - INSTITUT VON KARMAN DE DYNAMIQUE DES FLUIDES - - - EUR 3 876 853,68 - - - Uncertainty Treatment and OPtimisation In Aerospace Engineering - - - EUR 3 876 853,68 - - - United Kingdom - France - Italy - Italy - United Kingdom - Slovenia - Italy - Belgium - Germany - Germany - Belgium - - - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - - In an expanding world with limited resources and increasing uncertainty, optimisation and uncertainty quantification become a necessity. Optimisation can turn a problem into a solution, thus the main focus of this ETN is to - explore and develop new approaches to treat uncertainty in complex engineering systems and use novel optimisation techniques to efficiently deal with large scale problems with many objectives and uncertain quantities. It is generally recognised, in - fact, that neglecting the impact of uncertainty on the design of any system or process can lead to unreliable design solutions. Common approaches that make use of safety margins to account for uncertainty in design and manufacturing are not adequate - to fully capture the growing complexity of engineering systems and provide reliable and optimal solutions. - - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - UTOPIAE - - - H2020-MSCA-ITN-2016 - - - 722734 - - - - - KARLSRUHER INSTITUT FUER TECHNOLOGIE - IBM RESEARCH GMBH - - - EUR 515 332,70 - - - Capillary systems for advanced point-of-care diagnostics - - - EUR 515 332,70 - - - Germany - Switzerland - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The worldwide in vitro diagnostic (IVD) is continually growing. At least 36% of the IVD market comprises point-of-care (POC) tests, which are performed by healthcare professional in various settings or by patients themselves. - A large number of companies entered the POC testing market in the recent years while bringing significant technological improvements and novel concepts to this market. Yet, many important needs for immunodiagnostics are unmet: POC tests still require - relatively large volumes of samples, cannot readily be multiplexed, are not always accurate, and often involve simple liquid displacement ""from point A to point B"" with minimal control over the distribution of reagents and kinetics of reactions. - - 2021-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-EID - European Industrial Doctorates - - - Germany - - - CAPSYS - - - H2020-MSCA-ITN-2017 - - - 764476 - - - - - WEIZMANN INSTITUTE OF SCIENCE - WEIZMANN INSTITUTE OF SCIENCE - INTELLISIV LTD - - - EUR 150 000 - - - Quantum-dot doped polymer fibers for cheap and bright light sources. - - - EUR 150 000 - - - Israel - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - In optical microscopy low-cost solid state LEDs and lasers have replaced traditional light sources. Major drawbacks of such, typically fiber-coupled light sources are poor flexibility, low modularity and high cost. Since a - complete separate system is needed for every excitation color, the size of the economical investment is hindering the adoption of the technology directly contributing to improved research quality in multiple disciplines. - - 2017-06-30, closed project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2015 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Israel - - - QDLight - - - ERC-2015-PoC - - - 680132 - - - - - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - - - EUR 2 414 500 - - - Clonal Deletion versus Clonal Diversion: Footprints of Self-Tolerance in the T CellRepertoire - - - EUR 2 414 500 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Self-tolerance is a key feature of the immune system; its failure causes autoimmune diseases such as Multiple Sclerosis or Type-1-Diabetes. Remarkably, T cell tolerance operates via two fundamentally different mechanisms: - potentially dangerous cells are either eliminated (clonal deletion) or re-programmed to differentiate into regulatory T (Treg) cells (clonal diversion). Paradoxically, both tolerance modes can ensue from self-antigen-encounter in the thymus, and the - parameters specifying these opposing cell-fates remain poorly understood. Moreover, the relative contribution of clonal deletion versus clonal diversion to tolerance at the level of diverse immune cell repertoires has not been determined. In - particular, the paucity of antigen-specific cells is a major experimental obstacle to unravelling to what extent cells with shared autoreactive specificity, yet different T cell receptors (TCRs), are subject to either mode of tolerance. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - TOLERANCE FOOTPRINT - - - ERC-2016-ADG - - - 742290 - - - - - JIHOCESKA UNIVERZITA V CESKYCH BUDEJOVICICH - - - EUR 142 720,80 - - - Socs3 gene in oocyte maturation and fertilisation - a novel link between inflammation and infertility - - - EUR 142 720,80 - - - Czech Republic - - - Higher or Secondary Education Establishments - - Increasing maternal age, a prevalent trend in developed countries, negatively influences oocyte quality and consequently female fertility – 5% of all couples experience fertility problems arising from a physiological source in - the women. To develop novel approaches to prevent or treat infertility, a more complete understanding of oogenesis is required. The host laboratory has recently identified the Socs3 gene, to date associated only with roles in the immune system, as a - novel strong candidate regulating oogenesis. The project exploits a genetic approach to ablate the Socs3 gene from the female germ-line and addresses the role of Socs3 gene during mouse oocyte maturation and fertilisation, e.g. in correct chromosomal - segregation, followed by further detailed and cutting-edge functional characterisation. The results could lead to the identification of novel therapeutic targets to treat female infertility. Dr. Veselovska, coming from a world-renown institute, is - joining a well-established early mammalian development orientated host group, within the Department of Molecular Biology at the University of South Bohemia. Synergies arising from this multidisciplinary proposal will benefit both host and applicant. - In particular, Dr. Veselovska is bringing a wealth of highly relevant mouse oocyte experience and bioinformatics skills for genome-scale analyses that are currently an underrepresented skills set in the host laboratory and host institution, as well - as her network of UK based collaborators. She will receive training that is both complementary to her current knowledge and skills and novel and highly contemporary in relation to the experimental approaches used. Consequently, the fellowship award - will substantially further the Dr. Veselovska’s career ambitions to become an independent early mammalian developmental biologist within her native Central European region, and facilitate the under-represented exchange of ideas between Western and - Eastern European countries. - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Czech Republic - - - OOCSOCS - - - H2020-MSCA-IF-2015 - - - 708255 - - - - - UNIVERSITAET BASEL - UNIVERSITAET BASEL - - - EUR 1 500 000 - - - Bridging the gap between supramolecular chemistry and current synthetic challenges: Developing artificial catalysts for the tail-to-head terpene cyclization - - - EUR 1 500 000 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Nature is a rich source of biologically active molecules, among which the largest and most diverse group of natural products are terpenes. Essential drugs like the cancer medication taxol/paclitaxel or the malaria drug - artemisinin belong to the terpene family. They are efficiently formed in nature through a so-called tail-to-head terpene cyclization. Chemists are not able to mimic this process with man-made catalysts. This proposal aims at closing this significant - research gap by utilizing supramolecular chemistry. Learning how to design such complex catalysts will not only enable us to mimic natural enzymes, but to enter uncharted territory of terpene chemistry. - - 2021-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Switzerland - - - TERPENECAT - - - ERC-2016-STG - - - 714620 - - - - - SCUOLA NORMALE SUPERIORE - SCUOLA NORMALE SUPERIORE - - - EUR 2 151 875 - - - The Interstellar Medium of High Redshift Galaxies - - - EUR 2 151 875 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - When and how did the first galaxies form across Cosmic History? Were they different from present-day ones? This is only a small subset of key cosmological questions that the combination of deep galaxy observations, theoretical - modeling, and powerful simulations envisaged here will allow us to answer for the first time. - - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Italy - - - INTERSTELLAR - - - ERC-2016-ADG - - - 740120 - - - - - UNIVERSITY OF BATH - - - EUR 195 454,80 - - - Numbers in the brain: the impact of brain lateralization on numerical abilities - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Understanding the neural correlates of number cognition is of both intellectual and societal importance: number cognition gives fundamental insight into the evolution of cognitive processes and poor numeracy limits life - chances and is a substantial cost to nations. - - 2020-05-31, Grant Agreement signed - - - 2018-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - NUMELAT - - - H2020-MSCA-IF-2016 - - - 750200 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 185 076 - - - RAREFUNCTIONS: The causes and consequences of spatial and temporal variation in rare traits. - - - EUR 185 076 - - - France - - - Research Organisations - - Rare species have long been the focus of conservation attention, but the commonness or rarity of particular characteristics or phenotypes is generally ignored. However, traits can also be rare, and evidence suggests that while - rare traits tend to occur in rare species (and so are at greater risk of extinction), not all rare species have rare traits. Further, the diversity of traits present in a community (‘functional diversity’) is closely tied to its function, and so rare - traits may make essential contributions to ecosystem function and health. For example, predators may be rare in a system, but act as keystone species with effects across the food web. Given the possibility that rare traits make important - contributions to ecosystem products and services and given their greater risk of extinction, it is imperative to explore this question of “functional rarity”. This project will help overcome the lack of a clear definition for functional rarity, the - absence of geographical information on its distribution through space and time, and the need for experimental evidence tying the loss of rare traits to effects on ecosystems. This project aims to apply a system of classification to distinguish - between different forms of functional rarity to a comprehensive database of plant diversity and trait values in French permanent grasslands. This will produce one of the most comprehensive inventories showing how functional rarity varies through - space and time. In addition, RAREFUNCTIONS will use microbial microcosms to test how the loss of rare traits from a community alters ecosystem function. This proposal will establish baseline knowledge on the distribution of functional rarity in - French permanent grasslands, a local hotspot of biodiversity and in decline, while also answering general questions about the causes and consequences of rare traits. - - 2018-05-31, Grant Agreement terminated | - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - RareFunctions - - - H2020-MSCA-IF-2014 - - - 657951 - - - - - WEIZMANN INSTITUTE OF SCIENCE - WEIZMANN INSTITUTE OF SCIENCE - - - EUR 2 437 500 - - - Algorithms and experimental tools for integrating very large-scale single cell genomics data - - - EUR 2 437 500 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Robust and flexible tissue -and cell-type specific gene regulation- is a definitive prerequisite for complex function in any multi-cellular organism. Modern genomics and epigenomics provide us with catalogues of gene - regulatory elements and maps illustrating their activity in different tissues. Nevertheless, we are far from being able to explain emergence and maintenance of cellular states from such data, partly because we so far lacked characterization of - individual molecular states and genome control mechanisms at their native resolution -the single cell-. Recently, new approaches developed by the single cell genomics community, with several contributions from our group, allow massive acquisition of - data on the transcriptional, epigenomic and chromosomal conformation states in large cohorts of single cells. In this research program, we aim to move forward rapidly to bridge a major gap between these experimental breakthroughs and models of genome - regulation in complex tissues. We will develop algorithms and models for representing data the transcriptional profiles, DNA methylation landscapes and Hi-C maps of literally millions of cells. Our tools will be designed specifically to leverage on - new single cell RNA-seq, single cell Hi-C, single cell capture-pBat and higher order 4C-seq that we will continue to develop experimentally. Furthermore, we shall enhance and optimize our interdisciplinary framework hand in hand with a working model - aiming at unprecedentedly comprehensive single cell analysis of E8-E10 mouse embryos. This will provide us with hundreds of worked-out cases of tissue specific gene regulation. The techniques and insights from these studies will then be used to - characterize cell type aberrations and epigenetic reprogramming in tumors. The open algorithms, techniques and methodology we shall develop can accelerate research in multiple groups that will utilize single cell genomics to study numerous questions - on gene regulation in the coming years. - - 2022-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Israel - - - scAssembly - - - ERC-2016-COG - - - 724824 - - - - - UNIVERSITY COLLEGE LONDON - - - EUR 195 454,80 - - - Mechanical regulation of tissue growth and signalling - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The control of tissue size and morphology is a fundamental problem that is remarkably ill understood. Although extensive research has focussed on the genetic and biochemical control of tissue growth, significantly less - attention has been paid to the mechanical aspect of growth regulation, even though ample evidence indicates that any deformation or shape change is, to some degree, a result of force acting on a mass. Unravelling the basis of the - mechanical-biochemical co-regulation in tissue growth control will not only increase our understanding of organismal development but also potentially represent a novel therapeutic target in growth-related diseases such as cancer. With this in mind, I - aim to address two central questions: - - - 2017-12-31, Grant Agreement terminated | - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - MRTGS - - - H2020-MSCA-IF-2014 - - - 657088 - - - - - BALTIJOS PAZANGIU TECHNOLOGIJU INSTITUTAS - ALEKSANDRO STULGINSKIO UNIVERSITETAS - VIESOJI ISTAIGA SOCIALINIU INOVACIJU INSTITUTAS - KAUNO TECHNOLOGIJOS UNIVERSITETAS - LIETUVOS ISTORIJOS INSTITUTAS - VILNIAUS GEDIMINO TECHNIKOS UNIVERSITETAS VIESOJI ISTAIGA - VILNIAUS UNIVERSITETAS - VYTAUTO DIDZIOJO UNIVERSITETAS - - - EUR 140 405,75 - - - Researchers' Night: It's Your Friday to Discover! - - - EUR 140 405,75 - - - Lithuania - Lithuania - Lithuania - Lithuania - Lithuania - Lithuania - Lithuania - Lithuania - - - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - "The LT2016 Researchers’ Night projects for 2016 and 2017 will take place in major Lithuanian cities, i.e. Vilnius, Kaunas, Klaipeda, Siauliai and Moletai, as well as in rural areas. The project aims to enhance public - recognition of researchers and their work through bringing scientists and public closer to one another and thus increasing an understanding of the impact of researchers' work on citizen's daily life as well as encouraging young people to choose - careers in science and research. Both events will offer a broad range of varied activities addressing all categories of the public at large, regardless of age and scientific background, i.e. notably: Meetings and activities together with researchers; - Lectures, discussions; Visits to open laboratories; Real life observations and experiments; European corners; Various contests, games, exhibitions, movie and online broadcast watching. All the activities planned will actively involve researchers and - will offer a balanced combination of ""serious"" activities and funny ones to be attractive for the general public. Activities will be hosted in labs, lecture halls, meeting places, cafes, while in the rural areas they will take place in schools or - public spaces. Some activities conducted in the main sites will be broadcasted online. Common concept for the Night in 2016 and 2017 will be Learning about Technology Futures. Therefore activities of Researchers’ Night projects in 2016 will be - organised with focus on Virtual Reality thus building foundations for the Night in 2017 which will focus of ""science futurity"" or Futures of technologies. Both events will be finalised with the grand event unifying different fields - music, science - and cinema. We expect at least 500.000 people made aware of the Researchers' Night and its objectives through the awareness campaign and 11.500 direct attendees to the various events planned in 2016 as well as in 2017." - - 2017-11-30, closed project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.5."> - - - MSCA-NIGHT-2016 - European Researchers' Night - - - CSA - Coordination and support action - - - Lithuania - - - LT2016 - - - H2020-MSCA-NIGHT-2016 - - - 722959 - - - - - UNIVERSITY COLLEGE LONDON - - - EUR 183 454,80 - - - Supracellular contractility dynamics and cell communication during collective chemotaxis. - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Collective chemotaxis (CCT) is a fundamental process for embryonic development and cancer metastasis, where groups of cells collectively migrate in response to a chemoattractive signal. While single cell migration depends on - polarised actomyosin mechanotransduction and signalling cascades within the same cell, in CCT these functions are shared between different cells to achieve a coordinated, ‘‘supracellular’’ translocation. The molecular mechanisms underlying - coordination and cell-cell communication during CCT have been largely overlooked. I propose to address this issue using the neural crest (NC), a highly invasive mesenchymal cell population that migrates throughout the embryo via CCT. NC migration - shows extensive similarities with cancer invasion, making it a useful model for studying metastatic migration. Preliminary experiments show that an actomyosin ring-shaped cable, which surrounds the NC cluster, contributes to maintain a supracellular - organisation. Also, during CCT, gap junctions appear to regulate synchronous actomyosin contractions in cells located at the cluster’s rear. Therefore, I will study this contractility dynamics in-vitro and in-vivo using Xenopus and zebrafish. I will - manipulate the actomyosin cable to understand its contribution to efficient chemotaxis. Then, I will investigate how gap junctions enable synchronisation between neighbouring cells, by imaging the spread of calcium waves in NC clusters and - manipulating other diffusible messengers. This study will give significant insights into the mechanisms regulating CCT, which is crucial for deepening our understanding of morphogenesis and cancer biology. - - 2018-09-30, Grant Agreement terminated | - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SUPRACELL_COMMUN_CCT - - - H2020-MSCA-IF-2015 - - - 703100 - - - - - UNIVERSITY OF LEICESTER - - - EUR 183 454,80 - - - Urban Centres and Landscapes in Transition. The Mediterranean FarWest in Late Antiquity - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - MED-FARWEST is a strongly innovative project that, focussing on the territory located in the far west of the Roman Empire, namely the Iberian Peninsula, will analyse two of the most interesting yet poorly understood phenomena - of the crucial period of Late Antiquity (AD 300-700): 1. the complete abandonment of some cities and 2. the dismantling of the Roman rural world. Both phenomena have long seen consideration by a variety of independent researchers, but without - satisfactory depth and explanation to the issue. This proposed project will be the first to apply a comprehensive multidisciplinary approach, exploiting techniques developed especially in the sub-discipline of Landscape Archaeology, in which the - rural and urban worlds are analysed as a single unit, and thus as part of a single reality in transformation. Hispania provides an ideal ‘test-bed’ for the study given the results of new fieldwork, an availability of relevant sites (urban/rural), and - recent published outputs. The applicant and the proposed Host (University of Leicester) and Partner Organizations (the CSIC-National Research Council of Spain and CINECA of Italy) can draw upon a rich vein of expertise, specialists, research, - publications, equipment and infrastructure to generate data, models and results for this project. The approach to be developed will be of major value for addressing other aspects of Roman-late antique transformation in Hispania (urban, rural, social, - demographic, economic), but, crucially, will also provide guidelines for analyses elsewhere in the Empire, thus enabling much closer dialogue in approaches and debates both for Late Antiquity and for other periods. - - 2017-10-31, Grant Agreement terminated - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - MED-FARWEST - - - H2020-MSCA-IF-2014 - - - 658045 - - - - - THE HEBREW UNIVERSITY OF JERUSALEM - - - EUR 263 385 - - - Motor simulation: Evaluating the role of mirror neurons in humans through ECOG and Lesion Studies - - - EUR 263 385 - - - Israel - - - Higher or Secondary Education Establishments - - One of the most intriguing, yet controversial findings in neuroscience in the past two decades is the discovery of the mirror neuron system (MNS). These visuo-motor neurons discharge both when a monkey does a particular - goal-directed action and also when it observes another individual doing a similar action. The result of this mechanism is thought to be the capacity to recognize that an individual is performing an action, to differentiate this action from others - analogous to it, and to use this information in order to act appropriately. This mechanism has been proposed as the basis for social cognition, and deficits in social understanding, such as those seen in autism spectrum disorder, have been linked to - deficits in the MNS. Here I propose to use 2 novel approaches to address the neurobiological and behavioral significance of the human mirror neuron system (hMNS). (a) I will use Electrocorticography (ECoG) in neurosurgical patients to assess where, - when, and how neurons in the prefrontal, parietal and sensorimotor regions are involved in action recognition. (b) I will employ scalp EEG and behavioral measures in a unique cohort of patients with damage centered in the Inferior Frontal Gyrus (IFG) - or the Inferior Parietal Lobule (IPL). If the IFG and IPL are the core regions of the hMNS, patients with lesions to these regions should show deficits in understanding others’ actions, intentions and emotions (when these are expressed by body - motion). This research will further our knowledge on the neural underpinnings of social understanding, and on the consequences of deficits in these neural networks. - - 2018-06-30, Grant Agreement terminated - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Israel - - - MOTOR SIMULATION - - - H2020-MSCA-IF-2014 - - - 655292 - - - - - ISTITUTO NAZIONALE DI FISICA NUCLEARE - JOHANNES GUTENBERG-UNIVERSITAT MAINZ - UPPSALA UNIVERSITET - INSTITUTE OF HIGH ENERGY PHYSICS CHINESE ACADEMY OF SCIENCES - - - EUR 1 498 500 - - - An innovative Cylindrical Gas Electron Multiplier Inner Tracker for the BESIII Spectrometer - - - EUR 1 498 500 - - - Italy - Germany - Sweden - China - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - Inner Trackers (IT) are key detectors in Particle Physics experiments; excellent spatial resolution, radiation transparency and hardness, and operability under high occupancies are main requirements. While planar Gas Electron - Multiplier (GEM) detectors are common in modern spectrometers, only one Cylindrical-GEMs (CGEM) detector has been produced up to now by the KLOE2 Collaboration and is being commissioned. - - 2018-12-31, ongoing project | - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Italy - - - BESIIICGEM - - - H2020-MSCA-RISE-2014 - - - 645664 - - - - - UPPSALA UNIVERSITET - - - EUR 185 857,20 - - - The evolutionary and ecological implications of mito-nuclear epistasis - - - EUR 185 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - The main hypothesis of the proposed research is that, contrary to common and long-standing belief, mitochondrial genetic variation is functional and plays a key role in evolutionary adaptation. I suggest that a novel - understanding of selection on mtDNA can derive from simultaneously considering sex-specific selection and genetic interactions between mtDNA and nDNA. Because males are a genetic “dead-end” for mtDNA, mtDNA mutations that are detrimental for males - but beneficial for females will spread. This will generate a male-specific genetic load (“the mother’s curse”). Further, the main energy producing pathway in eukaryotes (the OXPHOS pathway) is built collectively by products of the mitochondrial and - the nuclear genome. Thus, mtDNA and nDNA are potentially entangled in an intricate web of epistatic interactions that dictates organismal metabolism. The proposed research is built upon a series of interrelated parts, and will use a very amenable - insect model organism and employ a range of different research methodologies. Specific aims of the proposed research is (1) to assess the effects of mito-nuclear genotype on key life history traits such as metabolic rate and test whether these - effects are sex-specific in line with the “mother’s curse” and (2) to test the hypothesis that mito-nuclear interactions promotes the maintenance of polymorphism in mitochondrial genome through negative frequency dependent selection. This research - will have a range of biological implications, ranging from applied medical genetics over our use of mitochondrial genetic markers in population genetics/biology to speciation and our understanding of thermal adaptation to climate change. - - 2017-09-30, closed project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - MITONUC - - - H2020-MSCA-IF-2014 - - - 656338 - - - - - ECOLE DES HAUTES ETUDES EN SCIENCES SOCIALES - - - EUR 173 076 - - - Humanitarian Passions. The Survival of Christian Iconography in Contemporary Representations of Pain: a Visual Studies Approach - - - EUR 173 076 - - - France - - - Higher or Secondary Education Establishments - - My research project aims at contributing to understanding the role played by mass communications in contemporary humanitarian crises, through a comparative study of representations of pain in the history of Western iconography. - - 2017-06-14, closed project - - - 2015-06-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - HumanitarianPassions - - - H2020-MSCA-IF-2014 - - - 658512 - - - - - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - BIOMEDICAL SCIENCES RESEARCH CENTER ALEXANDER FLEMING - FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA - THE UNIVERSITY OF EDINBURGH - Fundació Institut d'Investigació Biomèdica de Bellvitge - KAROLINSKA INSTITUTET - WEIZMANN INSTITUTE OF SCIENCE - DIAGENODE - UD-GENOMED MEDICAL GENOMIC TECHNOLOGIES KUTATAS-FEJLESZTESI ES SZOLGALTATO KFT - MOSAIQUES DIAGNOSTICS GMBH - AvantiCell Science Ltd - - - EUR 3 782 583,36 - - - Chromatin Dynamics in Development and Disease - - - EUR 3 782 583,36 - - - Greece - Germany - Greece - Italy - United Kingdom - Spain - Sweden - Israel - Belgium - Hungary - Germany - United Kingdom - - - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Chiara Andreoli - Tel.: +3901071781854 - Fax: +39 010 7170817 - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The cell nucleus is organized and compartmentalized into a highly ordered structure that contains DNA, RNA, chromosomal and histone proteins which make up a structure called chromatin. The dynamics associated with these - various components are responsible for regulating physiological processes and the overall stability of the genome. The destabilization of such regulatory mechanisms that act on the chromatin structure are implicated in pathologies such as cancer. - Higher order organization of chromatin results in chromosomes which occupy discrete territories within the cell nucleus. Most nuclear processes occur or at least being initiated onto the chromosomes which makes them the main organizing factors in the - nucleus. Several proteins that are involved in the replication of DNA, gene transcription and the processing of RNA are found enriched in discrete focal structures. An emerging question is how these structures assemble and are maintained in the - absence of membranes and moreover what are the kinetics of stable binding and/or rapid exchange of their components. The dynamic assembly and modification of chromatin during developmental processes as well as the deregulation of such chromatin - dynamics during the onset of disease lacks mechanistic insights at present. To address these questions we have put forward a multidisciplinary approach which involves molecular, cellular and systems level approaches by assembling a group of - scientists from academia and industry with cross disciplinary expertise and capabilities. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Greece - - - Chromatin3D - - - H2020-MSCA-ITN-2014 - - - 642934 - - - - - LULEA TEKNISKA UNIVERSITET - THE UNIVERSITY OF BIRMINGHAM - UNIVERSIDADE DE COIMBRA - UNIVERSITA DEGLI STUDI DI FIRENZE - TECHNISCHE UNIVERSITEIT EINDHOVEN - INSTITUT VON KARMAN DE DYNAMIQUE DES FLUIDES - RUHR-UNIVERSITAET BOCHUM - GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER - SIEMENS INDUSTRY SOFTWARE NV - SENVION GMBH - - - EUR 3 811 804,92 - - - Efficient harvesting of the wind energy - - - EUR 3 811 804,92 - - - Sweden - United Kingdom - Portugal - Italy - Netherlands - Belgium - Germany - Germany - Belgium - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - As wind energy is considered one of the most promising renewable energy resources, energy production technologies relying on wind energy are currently flourishing under the EU ambitious plan for 2020. Market demands to prepare - a generation of researchers within the EU that are able to face the challenge of fulfilling the EU ambitious plan, to sustain the production of wind energy and to innovate and promote wind energy systems (WES) for the future needs, are clearly met in - AEOLUS4FUTURE. The primary research aim is to develop a sustainable WES for a variety of EU needs. There are a number of detailed scientific and technical issues that will be addressed by the project starting from identifying the wind energy - potential (off-shore and on-shore, including the built environment) to the design of a sustainable and highly efficient WES. Also the new challenging load conditions imposed on wind farms located on places where existing type of wind turbine towers - are not suitable require the development of new type of support structures for wind energy converters. This fosters new structural concepts taking advantage of high performance materials e.g. high strength steel and novel maintenance free fasteners. - In addition, while most research efforts and practical applications of wind energy have focused on large-scale wind installations in remote offshore or onshore areas, much less attention has been given to wind energy installations near buildings. The - project has a major training aim to create technical experts who will be able to lead the necessary industrial developments in the WES, and have a broad overview of a new and emerging multi-disciplinary field. The project will thus enable a number of - young scientists and engineers to obtain high level training in various technical aspects of the problem, to gain an overall understanding of how this work fits into the wider EU Directives and plans for the future and in doing so to improve their - career prospects. - - 2018-12-31, ongoing project | - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Sweden - - - AEOLUS4FUTURE - - - H2020-MSCA-ITN-2014 - - - 643167 - - - - - ECOLE DES HAUTES ETUDES EN SCIENCES SOCIALES - - - EUR 185 076 - - - Global Inheritances: Personal Identification and Inheritance Rights in the Early Modern Spanish Empire - - - EUR 185 076 - - - France - - - Higher or Secondary Education Establishments - - The aim of the project is to study the ways in which the institutions of the early modern Spanish Empire identified the legitimate heirs of mobile individuals coming from the Iberian peninsula who died suddenly, often without - making a will, while they were in the monarchy’s extra-European territories, thousands of kilometres away from their home towns and the places where their heirs lived. In the context of a global scale empire, and in the absence of reliable official - documentation such as civil and property registers, both the property and identity of these mobile individuals was extremely uncertain. Who were the deceased? What property did they own? Who and where were their heirs? When they died thousands of - kilometres away from Europe, how did the institutions transmit the inheritance to their legitimate heirs? How could the courts be sure who they were? How could heirs demonstrate their identities in order to safeguard their rights to succession? For - those hundreds of thousands of subjects of the Catholic Monarchy now on the move around four different continents – and for their families too – identifying themselves and demonstrating their identities was an urgent and growing need. - - 2017-08-31, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - GLOBAL INHERITANCES - - - H2020-MSCA-IF-2014 - - - 655316 - - - - - PERCUROS BV - ACADEMISCH ZIEKENHUIS LEIDEN - PROGREDUM GMBH - TECOBIOSCIENCES GMBH - ANTONETTI NADIA - UNIWERSYTET JAGIELLONSKI - UNIVERSITAETSMEDIZIN GOETTINGEN - GEORG-AUGUST-UNIVERSITAET GOETTINGEN - STIFTUNG OEFFENTLICHEN RECHTS - PREVENTIA SOCIETA' A RESPONSABILITA' LIMITATA SEMPLIFICATA - UNIVERSITA DEGLI STUDI DI CAMERINO - BOURNEMOUTH UNIVERSITY - ATONOMICS AS - TACIT BIO INNOVATION LIMITED - DE MARCHIS VERONICA - ASSOCIAZIONE CULTURALE CASTELLI ROMANI GREEN TOUR - AUGEAS ASSOCIAZIONE DI SPORT PROMOZIONE E TURISMO - SYDDANSK UNIVERSITET - HELRIK AND LOUW COMPANY LTD - TECHNICKA UNIVERZITA VO ZVOLENE - - - EUR 2 430 000 - - - Characterisation Of A Green Microenvironment And To Study Its Impact Upon Health and Well-Being in The Elderly As A Way Forward For Health Tourism. - - - EUR 2 430 000 - - - Netherlands - Netherlands - Germany - Germany - Italy - Poland - Germany - Italy - Italy - United Kingdom - Denmark - United Kingdom - Italy - Italy - Italy - Denmark - United Kingdom - Slovakia - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Other - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - Our society in Europe is still under prepared for the demographic changing situation of an ageing population which began several decades ago. This is visible in the age structure of the population and is reflected by the fact - that the population aged 65 years and over is increasing in every European country. The growth in the elderly population may be explained by increased longevity, but at the same time, we also see an increase in debilitating conditions. However, it is - also clear that the elderly are afflicted by challenging health conditions as a direct consequence of being elderly which impact their quality of life (QOL), e.g. living alone, depression, recovery from illness, immobility. This is what we would like - to address. Living longer should be a privilege but there has been a collective failure to address social implications and QOL issues, where social care and the way it is funded are already in crisis. Our aim in this project is to couple the need for - new societal approaches in addressing this changing demographic with improving the economy of green microenvironment sites, where health tourism and creating new jobs in this sector would in turn fund and provide benefits with respect to the - well-being of the elderly. The ultimate outcome, through this pan-European academic and industrial project, will be: a) to derive cross-disciplinary and inter-sectorial knowledge of how to improve physical and mental well-being in the elderly, b) to - characterise the environmental geology of Nemi and to correlate the identified features with improvements in health, well-being and recovery, c) to train a new generation of specialists in the sector of recreation and health for the tourism industry, - d) the training of specialists in social and therapeutic horticulture (STH) as a way to improve physical and mental health, e) to create a model for health tourism, and f) to produce a business plan with an economic impact analysis. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Netherlands - - - CHARMED - - - H2020-MSCA-RISE-2016 - - - 734684 - - - - - UNIVERSITAET BERN - - - EUR 187 419,60 - - - Evidence Based Planning of Future Clinical Research - - - EUR 187 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - Clinical studies that are planned without prior consideration of existing evidence potentially experiment with an unnecessarily large number of patients or try to answer a question to which the answer is already available. - This project aims to develop a framework of efficient and sustainable research planning that minimizes cost and has the potential to direct resource allocation by optimally planning future clinical studies based on existing evidence. A circular - updating process is suggested; before a trial is planned the existing evidence (a network meta-analysis) about the effectiveness of all competing interventions is considered and its conclusiveness is statistically evaluated. If further experiments - are needed these are designed considering patient’s preferences and with an aim to render the existing evidence conclusive. The new data is then used to update the existing knowledge. This innovative approach to plan clinical studied requires - methodological developments from various fields (biostatistics, operational research, epidemiology) and its feasibility will be evaluated in answering a real clinical question about the best intervention for a given condition and in designing a new - trial. The circular updating process is of high interest to public research funding bodies, guideline developers and pharmaceutical companies. The project has a strong public engagement component as patients and major health care organizations are - involved in many of the planned activities in the development of the circular updating process. The project will be carried out in a stimulating academic environment (University of Bern) with extensive experience in clinical trials and a secondment - in Novartis is planned. I will acquire technical skills in clinical trials, will continue to produce high-impact publications and develop leadership skills. These additions to my curriculum will enable me to progress to an academic carrier in a - high-profile European Institute. - - 2018-05-31, ongoing project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - EBAR - - - H2020-MSCA-IF-2015 - - - 703254 - - - - - ECOLE DES HAUTES ETUDES EN SCIENCES SOCIALES - - - EUR 185 076 - - - Enacting heritage: The aesthetic dynamics of cultural transmission - - - EUR 185 076 - - - France - - - Higher or Secondary Education Establishments - - Aesthetic behaviours and expressive activities carry out a crucial role in human cultural evolution. Aesthetic cognition is important for intersubjective attunement already in early childhood, and attends to cultural emergence - and transmission of ideas, practices and norms. However, anthropological scholars haven't ever investigated the cognitive dynamics whereby aesthetic behaviours shape the symbolic processes of constitution and re-enactment of cultural heritage. The - proposed research project seeks to address this lacuna by dealing with key issues relating to the role of aesthetic behaviours in cultural transmission. The study focuses on how aesthetic and expressive elements are mobilized in the course of social - interaction creatively transforming and communicating knowledge. - - 2018-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - EnAct - - - H2020-MSCA-IF-2014 - - - 655942 - - - - - UNIVERSITY OF SOUTHAMPTON - INSTITUTO SUPERIOR DE ENGENHARIA DE LISBOA - UPPSALA UNIVERSITET - HELSINGIN YLIOPISTO - UNIVERSITE PARIS-SUD - CARLETON UNIVERSITY - THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - University of Toyama - ZEWAIL CITY OF SCIENCE & TECHNOLOGY - UNIVERSITE ABDELMALEK ESSAADI - - - EUR 301 500 - - - Non Minimal Higgs - - - EUR 328 500 - - - United Kingdom - Portugal - Sweden - Finland - France - Canada - United States - Japan - Egypt - Morocco - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - - On July 4th CERN has announced the discovery of a scalar particle at the Large Hadron Collider (LHC), later identified as the Higgs boson. This scientific breakthrough was accomplished due to the joint efforts of thousands of - scientists from all around the globe. This long awaited discovery increased our understanding of the world, providing an explanation for the mechanism from which all elementary particles acquire mass. However, there are still fundamental questions - awaiting a clear answer: which model better describes nature when all observed properties of this new particle are taken into consideration? Will these new models help to solve other outstanding problems in elementary particle physics? The goal of - this project is to look for answers to these crucial questions regarding our understanding of nature. - - 2019-05-31, ongoing project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - United Kingdom - - - NonMinimalHiggs - - - H2020-MSCA-RISE-2014 - - - 645722 - - - - - UPPSALA UNIVERSITET - - - EUR 173 857,20 - - - Combining Single Molecule and Ensemble approaches To Investigate Cas9 Target Search - - - EUR 173 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - The CRISPR-Cas9 bacterial immune system has garnered intense interest both as a synthetic biology tool and as a biological system in its own right. Yet the ability of Cas9 to find its guide-RNA-directed binding site in a - timely fashion remains mysterious. To find its binding site, the single-stranded guide RNA must recognize the appropriate homologous DNA target within double-stranded chromosomal DNA, without using ATP to melt dsDNA. Moreover, in vitro measurements - of Cas9 target search seem to suggest that an individual Cas9 molecule should take on the order of months to discover its target site, far too long to defend against viral infections which can proceed to lysis in less than one hour. To begin to - unravel these conundrums, I plan to measure Cas9 target search time in vivo, using both single molecule and bulk approaches. The single molecule assay will use fluorescently tagged dCas9 (a version of Cas9 non-functional for cleavage) targeted - against the lac O1 binding site. At t=0 the synthetic inducer IPTG can be flowed in, dissociating LacI from the O1 binding site, and the amount of time needed for dCas9 to bind determined by time-lapse fluorescence microscopy. The bulk version of the - assay will exploit the existence of a binding site for the restriction enzyme BsrBI in the lacO1 binding site. As in the single molecule assay, the clock is started by addition of IPTG to growing cells, and the time needed for dCas9 binding is - quantified by observed how long is needed for dCas9 to confer protection against BsrBI cleavage of cross-linked and purified chromatin. Finally, I will perform high-speed tracking experiments on searching dCas9 molecules using electroporated - fluorescent dye-labeled guide RNAs. These measurements should constrain mechanistic hypotheses about Cas9 target search, and may provide insight into other critical biological processes involving single stranded nucleic acids searching in double - stranded nucleic acids, such as homologous recombination. - - 2018-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - CasMETICS - - - H2020-MSCA-IF-2015 - - - 704206 - - - - - FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA - - - EUR 168 277,20 - - - Stochastic Multi-Scale Modelling for the Analysis of Closed-Loop Interactions among Brain Networks - - - EUR 168 277,20 - - - Italy - - - Research Organisations - Chiara Andreoli - Tel.: +3901071781854 - Fax: +39 010 7170817 - - Brain functions likely emerge from the concerted, context-dependent operations of its microscopic and macroscopic networks. Therefore, the organization and operational principles of such complex systems may be best - investigated by using multi-modal approaches, including concurrent measurements of neural activity on multiple spatiotemporal scales. Performing and interpreting such multi-scale measures, though, presents enormous challenges for both experimental - and mathematical neuroscientists. Existing analysis methods, however, make limited use of newly acquired concurrent multi-scale information. To dramatically advance analysis methods for these data, I propose a novel multi-scale model that bridges the - gap between single cell statistics and neural mass signals. The model describes mixed discrete statistics, covering single cell and small population spike trains, as well as continuous statistics, such as those describing mesoscopic and macroscopic - measures of mass neural activity in neuroimaging experiments. These elements are combined by means of copulas, describing multivariate interactions within and between scales of activity. I will extend this method to the level of efficient - applicability and, in the course of a secondment with Prof. Logothetis at the Max Planck Institute in Tübingen, exploit the technique to solve current problems of multi-scale analysis of interactions between cortical and subcortical brain areas. The - new mathematical approach will lead to a set of new tools that I will disseminate in an Open Source format for maximal impact, and will be widely applicable to multi-modal recordings in animals and humans, in both research and clinical settings. My - own application of this method to multi-modal datasets will establish a deeper general understanding of the mechanisms of large-scale communication among brain areas, with particular emphasis on the principles of communication among networks involved - in the formation of declarative memory. - - 2017-06-30, closed project | - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - STOMMAC - - - H2020-MSCA-IF-2014 - - - 659227 - - - - - THE MANCHESTER METROPOLITAN UNIVERSITY - - - EUR 183 454,80 - - - House and home: physical and emotional comfort in the country house, England and Sweden c.1680-1820 - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Physical comfort and emotional well-being are common expectations and aspirations across 21st-century Europe. This fellowship explores an important episode in the historical development of these cultural and social norms. The - 18th century was a time when the wealthy, at least, had access to a growing range of goods, commodities and technologies, and were becoming increasingly aware of their individual identity. The research focuses on the changing relationship between - physical and emotional comfort in the context of the country house, and explores a number of key questions about how the desire for comfort related to gender and life course, and to material objects and the growing specialisation of domestic spaces; - how it was perceived through different senses and how it was juxtaposed with feelings of discomfort; and how it was conceived and experienced in two contrasting countries within Europe – places with very different societies, economies and climates. - - 2017-09-30, closed project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - HAHPEC - - - H2020-MSCA-IF-2014 - - - 658812 - - - - - ECOLE DES HAUTES ETUDES EN SCIENCES SOCIALES - - - EUR 185 076 - - - Popular readers and clandestine literature: the case of an early modern translation of Petronius’ Satyricon into Italian (17th C.) - - - EUR 185 076 - - - France - - - Higher or Secondary Education Establishments - - The project aims at an in-depth inquiry into a 17th-century unpublished manuscript bearing the translation of Petronius’ Satyricon into Italian. The translation represents a unique document, not only because it is likely to be - the first version of Petronius into a modern language, but also because it proves the diffusion of the Satyricon even within the public of popular readers. - - 2018-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - France - - - PopClandSATYRICON - - - H2020-MSCA-IF-2015 - - - 707253 - - - - - UPPSALA UNIVERSITET - - - EUR 173 857,20 - - - Bridging the gap: an evolutionary genomics approach to illuminate the prokaryote-to-eukaryote transition. - - - EUR 173 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - Eukarya – one of the three Domains of Life along with Archaea and Bacteria (i.e. prokaryotes) – include all complex multicellular life forms, as well as a colossal diversity of unicellular microorganisms. At the cellular - level, the gap between prokaryotes and eukaryotes is immense, with the latter cell types displaying a large number of complex subcellular organelles and molecular systems. The evolutionary origin of these unique features, and thus of the eukaryotic - cell itself, remains one of the most fascinating enigmas in modern biology. Although many eukaryotic-signature proteins (ESPs) are known to trace back to the last eukaryotic common ancestor, their deeper evolutionary origins remain unclear. The major - goal of the current proposal is to illuminate the prokaryote to eukaryote transition by elucidating the origin and subsequent evolution of ESPs, as well as their order of emergence. We will focus on the ESPs of archaeal origin with an emphasis on the - specific contribution of the newly discovered Lokiarchaeota lineages to the origin of the eukaryotic cell. In addition, we will aim to determine the placement the eukaryote lineage within the tree of Life and infer the age of the “first eukaryote”. - Finally, we will use a novel phylogenomic approach to infer the gene content of the archaeal ancestors of eukaryotes by mapping the evolution of ESPs along the tree of Life. For this purpose, we will analyse entirely novel genomic data from several - uncultivated Lokiarchaeota lineages, as well as novel sequence data from deep-branching key eukaryotes. This project will integrate approaches from distinct disciplines within life sciences and computational sciences (including molecular evolution, - genomics/metagenomics and cell biology), with a strong emphasis on phylogenomics. Altogether, the innovative nature of this work combined with state-of-the-art methods and novel key genome data will allow to gain unprecedented insights in the origin - and early evolution of Eukarya. - - 2018-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - Gap2bridge - - - H2020-MSCA-IF-2015 - - - 704263 - - - - - UNIVERSITAET BERN - UNIVERSITAET BERN - - - EUR 1 498 478 - - - Characterizing Adaptation and Migration Events with Modern and Ancient Genomes - - - EUR 1 498 478 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - BACKGROUND Ancient DNA research has recently entered the genomics era. Performing “ancient population genomics” is now technically possible. Utilizing the temporal aspect of this new data, we can address fundamental - evolutionary questions such as the amount of selection acting on the genome or the mode and tempo of the colonization of the world. AIMS The overall goal of the proposed research is to (i) generate and analyse data to answer two long standing - questions in human evolution: understanding the molecular basis of human adaptation to high altitude and investigating the timing of the Polynesian-South American contact, (ii) develop statistical approaches that combine ancient and modern genetic - data to estimate the timing and the intensity of a selective sweep and an admixture event. METHODOLOGY Application: We will collect, date and DNA sequence human remains. Combining the ancient genetic data, 14C dates with existing modern genomic data - will allow us to increase the resolution as to the timing of the adaptive and the admixture event, respectively, while generating unique datasets. Theory: We will build on existing methods based on one-locus classical population genetic models to - develop tools to analyse whole genome time serial data. RELEVANCE Ecological: The results will address the fundamental question of how much of the human genome is undergoing selection, better characterize one of the textbook examples of adaptation in - humans and contribute to our understanding of the peopling of the Americas. Medical: We will gain insights into the fundamental stress physiology experienced at high altitude and therefore into altitude-related illnesses. Methodological: The methods - developed in this project will not only benefit the growing field of ancient genomics but also other fields where data is collected in a temporal manner, such as experimental evolution and epidemiology - - 2021-07-31, ongoing project - - - 2016-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Switzerland - - - CAMERA - - - ERC-2015-STG - - - 679330 - - - - - UPPSALA UNIVERSITET - UPPSALA UNIVERSITET - - - EUR 1 621 940 - - - Contexts, networks and participation: The social logic of political engagement - - - EUR 1 621 940 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The statement that individuals’ immediate social circumstances influence how they think and act in the political sphere is a truism. However, both theoretical and empirical considerations have often prevented political - scientists from incorporating this logic into analyses of political behavior. In the CONPOL project we argue that it is necessary to return to the idea that politics follows a social logic in order to push the theoretical and empirical boundaries in - explaining political behavior. That is, people do not act as isolated individuals when confronting complex political tasks such as deciding whether to vote and which party or candidate to vote for. Instead politics should be seen as a social - experience in which individuals arrive at their decisions within particular social settings: the family, the peer group, the workplace, the neighborhood. In what way do parents and other family members influence an individual’s political choices? - What is the role of workmates and neighbors when individuals arrive at political decisions? Do friends and friends’ friends affect how you think and act in the political sphere? To answer such questions the standard approach to gather empirical - evidence on political behavior based on national sample surveys needs to be complemented by the use of population wide register data. The empirical core of the CONPOL project is unique Swedish register data. Via the population registers provided by - Statistics Sweden it is possible to identify several relevant social settings such as parent-child relations and the location of individuals within workplaces and neighborhoods. The registers also allow us to identify certain network links between - individuals. Furthermore, Statistics Sweden holds information on several variables measuring important political traits. A major aim for CONPOL is to complement this information by scanning in and digitalizing election rolls with individual-level - information on turnout across several elections. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Sweden - - - CONPOL - - - ERC-2015-CoG - - - 683214 - - - - - FRIEDRICH-SCHILLER-UNIVERSITAT JENA - FRIEDRICH-SCHILLER-UNIVERSITAT JENA - - - EUR 1 965 917 - - - Unifying concepts in the topological design of non-crystalline materials - - - EUR 1 965 917 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Glasses have traditionally been enabling materials to major societal challenges. Significant breakthroughs on many areas of technological progress have been very closely linked to the exploitation of glassy materials. It is - strong consensus that this key role will persist in the emerging solutions to major global challenges in living, energy, health, transport and information processing, provided that the fundamental limitations of the presently available empirical or - semi-empirical approaches to glass processing can be overcome. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - UTOPES - - - ERC-2015-CoG - - - 681652 - - - - - UPPSALA UNIVERSITET - UPPSALA UNIVERSITET - - - EUR 1 500 000 - - - Evolutionary Stability of Ubiquitous Root Symbiosis - - - EUR 1 500 000 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Virtually all terrestrial plants depend on symbiotic interactions with fungi. Arbuscular mycorrhizal (AM) fungi evolved over 450 million years ago, are obligate biotrophs and cannot complete their lifecycle without obtaining - carbon from host roots. Mediating nutrient uptake and sequestering carbon in soil this symbiosis lie at the core of all terrestrial ecosystems. Plants on the other hand are facultative mycotrophs but under natural conditions all host roots are - colonized as a result of multiple beneficial effects of AM fungi. In the symbiosis, both plants and fungi are promiscuous, forming interactions across individuals and species. In the absence of host-symbiont specificity and given their inability to - discriminate among partners prior to interaction, evolutionary theory predicts that “free riders” would evolve and spread. Yet AM fungi remain evolutionary and ecologically successful. I propose that this is thanks to their unique genomic - organization, a temporally dynamic heterokaryosis. - - 2021-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Sweden - - - HeteroDynamic - - - ERC-2015-STG - - - 678792 - - - - - UNIVERSITAET BERN - UNIVERSITAET BERN - - - EUR 1 999 437,50 - - - Synthetic viability of homologous recombination-deficient cancers - - - EUR 1 999 437,50 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Although various effective anti-cancer drug treatments have become available over the last decades, drug resistance remains the major cause of death of cancer patients. Striking examples are patients with tumors that are - defective in DNA repair by homologous recombination (HR). Despite initial responses to cancer therapy, resistance of primary or disseminated tumors eventually emerges, which minimizes therapeutic options and greatly reduces survival. The molecular - mechanisms underlying this therapy escape are often poorly understood. - - 2021-06-30, ongoing project - - - 2016-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Switzerland - - - SYNVIA - - - ERC-2015-CoG - - - 681572 - - - - - UNIVERSITA CA' FOSCARI VENEZIA - UNIVERSITA CA' FOSCARI VENEZIA - ECOLE DES HAUTES ETUDES EN SCIENCES SOCIALES - - - EUR 1 480 625 - - - Bilingualism in Florentine and Tuscan Works (ca. 1260 - ca. 1416) - - - EUR 1 480 625 - - - Italy - Italy - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project will undertake the first systematic investigation of the various literary documents that circulated simultaneously in more than one language in Tuscany, and especially Florence, between the mid-13th Century and - the beginning of 15th Century. - - - 2020-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Italy - - - BIFLOW - - - ERC-2014-STG - - - 637533 - - - - - HEINRICH-HEINE-UNIVERSITAET DUESSELDORF - HEINRICH-HEINE-UNIVERSITAET DUESSELDORF - - - EUR 2 499 457,50 - - - hybridFRET - deciphering biomolecular structure and dynamics - - - EUR 2 499 457,50 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - To understand and modulate biological processes, we need their spatiotemporal molecular models. In this project we propose to build these models by a holistic approach. The recent methodological and technical advances in - fluorescence spectroscopy and microscopy as well as in multi-scale modelling of complex biochemical systems set the stage to tackle cross-fertilizing challenges in biophysics, biochemistry and cell biology. The applicant proposes to develop a novel - integrative platform for a Molecular Fluorescence Microscope (MFM) to achieve ultimate resolution in space (sub-nanometer) and time (picoseconds) for characterizing structure and dynamics of proteins. MFM will combine Multi-parameter Fluorescence - Detection with Computational Microscopy (molecular dynamics and coarse grained simulations) in a hybrid approach, first, to derive a complete molecular description of all fluorescence properties of the tailored dyes in proteins (objectives 1 and 2) - and, second, to utilize this information in simulations to report on the protein properties (objective 3). In this hybrid approach high precision FRET measurements are the core experimental technique (hybridFRET). The MFM will allow us to tackle the - central biophysical question of how intra- and intermolecular domain interactions modulate proteins' overall structure, dynamics, and thus ultimately function (objective 4). In this proposal we will apply MFM to two prototypic proteins of significant - medical relevance. The combination with Multi-parameter Fluorescence Image Spectroscopy will exploit the ultimate resolution of the MFM for molecular protein imaging in live cells. To follow and ultimately understand biological processes, we need - their spatiotemporal models of the integrative fluorescence spectroscopy platform. Until now, no holistic use of fluorescence spectroscopy for structural modelling of proteins has been reported. - - 2020-11-30, ongoing project - - - 2015-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - hybridFRET - - - ERC-2014-ADG - - - 671208 - - - - - UPPSALA UNIVERSITET - UPPSALA UNIVERSITET - - - EUR 1 968 750 - - - Fundamental and Applied Science on Molecular Redox-Catalysts of Energy Relevance in Metal-Organic Frameworks - - - EUR 1 968 750 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Organometallic redox-catalysts of energy relevance, i.e. water and hydrogen oxidation, and proton and carbon dioxide reduction catalysts, will be incorporated into metal-organic frameworks (MOFs). Immobilization and spatial - organization of the molecular catalysts will stabilize their molecular integrity and ensure longevity and recyclability of the resulting MOFcats. The organized environment provided by the MOF will enable the control of conformational flexibility, - diffusion, charge transport, and higher coordination sphere effects that play crucial roles in enzymes, but cannot be addressed in homogenous solution and are thus largely unexplored. The effect that the MOF environment has on catalysis will be - directly probed electrochemically in MOFcats that are immobilized or grown on electrode surfaces. In combination with spectroscopic techniques in spectroelectrochemical cells, intermediates in the catalytic cycles will be detected and characterized. - Kinetic information of the individual steps in the catalytic cycles will be obtained in MOFs that contain both a molecular photosensitizer (PS) and a molecular catalyst (PS-MOFcats). The envisaged systems will allow light-induced electron transfer - processes to generate reduced or oxidized catalyst states the reactivity of which will be studied with high time resolution by transient UV/Vis and IR spectroscopy. The acquired fundamental mechanistic knowledge is far beyond the current - state-of-the-art in MOF chemistry and catalysis, and will be used to prepare MOFcat-based electrodes that function at highest possible rates and lowest overpotentials. PS-MOFcats will be grown on flat semiconductor surfaces, and explored as a novel - concept to photoanode and -cathode designs for dye-sensitized solar fuel devices (DSSFDs). The design is particularly appealing as it accommodates high PS concentrations for efficient light-harvesting, while providing potent catalysts close to the - solvent interface. - - 2021-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Sweden - - - MOFcat - - - ERC-2015-CoG - - - 681895 - - - - - UPPSALA UNIVERSITET - UPPSALA UNIVERSITET - - - EUR 1 525 000 - - - Mosaic loss of chromosome Y (LOY) in blood cells - a new biomarker for risk of cancer and Alzheimer’s disease in men - - - EUR 1 525 000 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - My recent discoveries show that mosaic loss of chromosome Y (LOY) in peripheral blood is associated with increased risks of cancer and Alzheimer’s disease (AD). These conditions are responsible for >50% of - morbidity/mortality in aging men. More than 15% of men older than 70 show some degree of LOY and these men survive on average only half as long as men without LOY. Smoking is strongly associated with LOY and remarkably, the fraction of cells with LOY - decreases after cessation of smoking. Cells with LOY can be detected, and disease risks predicted, many years before clinical manifestation of disease. These results of associations between LOY, cancer and smoking have been published in Nature - Genetics and Science during 2014. - - 2021-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Sweden - - - DIALOY - - - ERC-2015-STG - - - 679744 - - - - - UNIVERSITAET BERN - UNIVERSITAET BERN - - - EUR 1 928 125 - - - Dissection of a cortical microcircuit for the processing of pain affect - - - EUR 1 928 125 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - It is a fundamental but still elusive question how nociceptive processing is performed in neuronal networks in the cortex for the conscious experience of pain. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Switzerland - - - CorPain - - - ERC-2015-CoG - - - 682905 - - - - - UNIVERSITAET LEIPZIG - UNIVERSITAET LEIPZIG - - - EUR 1 772 625 - - - Form-frequency correspondences in grammar - - - EUR 1 772 625 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project will document and explain a substantial number of grammatical universals by demonstrating a link between cross-linguistic patterns of language form and general trends of language use. The claim is that frequently - expressed meanings tend to be expressed by short forms, not only at the level of words, but also throughout the grammars of languages around the world (form-frequency correspondences). A simple example is the asymmetry in the coding of present-tense - forms and future-tense forms in the world’s languages, as one out of a multitude of analogous cases: Present-tense forms tend to be short or zero-coded, while future-tense forms tend to be longer or to have an overt marker. This corresponds to a - usage asymmetry: Present-tense forms are generally more frequent than future-tense forms, in all languages. The proposed explanation is that higher-frequency items are more predictable than lower-frequency items, and predictable content need not be - expressed overtly or can be expressed by shorter forms. Form-frequency correspondences thus make language structure more efficient, but it still needs to be shown that there exists a mechanism that creates and maintains these efficient structures: - recurrent instances of language change driven by the speakers’ preference for user- friendly utterances. The project thus combines cross-linguistic research on grammar, cross-linguistic corpus research and historical linguistics in a ground- breaking - way. For reasons that have to do with the history of the discipline, form-frequency correspondences are still largely overlooked and ignored by linguists, so the current project will have a significant impact on our general understanding of human - language. - - 2020-10-31, ongoing project | - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - FormGram - - - ERC-2014-ADG - - - 670985 - - - - - UNIVERSITAET BERN - UNIVERSITAET BERN - - - EUR 1 953 000 - - - Mechanisms of RNA-guided genome editing in eukaryotes - - - EUR 1 953 000 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The goal of this project is to contribute to our understanding of RNA-mediated epigenetic mechanisms of genome regulation in eukaryotes. Ciliated protozoa offer a fantastic opportunity to investigate the complex process of - trans-generational programming of chromosomal rearrangements, which is thought to serve as a form of immune defense against invasive DNA. Developmental processes in ciliates include extensive rearrangements of the germline DNA, including elimination - of transposons and the precise excision of numerous single-copy elements derived from transposons. This process is considered to be maternally controlled because the maternal genome provides essential information in the form of RNA that determines - the offspring's genome content and organization. This programmed DNA subtraction, the so-called ‘RNA scanning’ process, is mediated by trans-generational comparison between the germline and the maternal somatic genome. One of the most intriguing - questions is how a complex population of small RNAs representing the entire germline genome can be compared to the entire rearranged maternal genome, resulting in the efficient selection of germline-specific RNAs, which are able to target DNA - deletions in the developing genome. All this occurs in a very short time and involves a massively coordinated transport of all the components between three types of nuclei. This project focuses on characterizing the molecular machinery that can - orchestrate the massive genome rearrangements in ciliates through nucleic acids and protein interactions. It also addresses the question how RNA targets DNA cleavage at the right place. In addition, this project aims to investigate the role of RNA in - guiding chromosomal rearrangements in other eukaryotic systems, particularly in human cancer cells where genome editing often occurs on a large scale. This work may be the first step in providing novel insights into the process of programmed DNA - rearrangements in higher eukaryotes. - - 2021-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Switzerland - - - G-EDIT - - - ERC-2015-CoG - - - 681178 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - UPPSALA UNIVERSITET - FUNDACIO CENTRE DE REGULACIO GENOMICA - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - VIB - THE UNIVERSITY OF EXETER - LUNDS UNIVERSITET - THE UNIVERSITY OF LIVERPOOL - ASCIDEA COMPUTATIONAL BIOLOGY SOLUTIONS SL - - - EUR 3 889 393,20 - - - Promoting SINgle cell GEnomics to explore the ecology and evolution of hidden microeuKaryotes - - - EUR 3 889 393,20 - - - Spain - Sweden - Spain - France - Belgium - United Kingdom - Sweden - United Kingdom - Spain - - - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Environmental microbial surveys have revealed a remarkable diversity of microeukaryotic life in most ecosystems, the majority of which had previously escaped detection. From an ecological point of view this work highlighted - our ignorance of critical microbial players in natural environmental processes, including primary production, biogeochemical cycling and trophic interactions such as parasitism and grazing. Consequently, our understanding of community function is - partial, limiting our ability to study environmental change. While, from an evolutionary perspective, we are missing major components of the Tree of Life giving rise to a fragmented understanding of how major cellular functions have evolved. Single - cell genomics (SCG), including single cell transcriptomics, is an emerging technology that has the potential to retrieve genomic information from individual uncultured microbes recovered directly from natural environments and promises to provide new - tools to investigate microeukaryotes in unparalleled detail. The aim of this ITN is therefore to train a new generation of scientists with the highest expertise, in SCG, from the initial stages of cell sorting to genome sequencing and gene - annotation, to the full exploitation of the data obtained. Such progress will allow the European research community for the first time to address critical ecological and evolutionary questions. SINGEK will drive training through research by both - local and network-wide activities, secondments, and workshops, and by establishing an environment that extends far beyond each partner team. This training environment will also provide the transferable skills essential for successful career - development. This network of well connected and highly qualified scientists with expertise in eukaryotic SCG will be ready to implement this technology beyond ecology and evolution to other fields such as biomedicine or biotechnology driving - innovation across the EU. - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Spain - - - SINGEK - - - H2020-MSCA-ITN-2015 - - - 675752 - - - - - FRIEDRICH-SCHILLER-UNIVERSITAT JENA - FRIEDRICH-SCHILLER-UNIVERSITAT JENA - - - EUR 2 373 750 - - - Multi-dimensional interferometric amplification of ultrashort laser pulses - - - EUR 2 373 750 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Ultrafast lasers, which allow the concentration of light in space and time, have been instrumental in revolutionizing industrial production technologies, medical applications and cutting-edge fundamental research. A common - demand for many applications is the combination of maximum pulse peak powers with maximum average powers, in extreme cases involving petawatt (PW) peak powers and megawatt (MW) average powers. Additionally, these parameters must be achieved together - with an optimum beam quality and high efficiency. The MIMAS project aims to address these demands and enable new realms of performance for ultrafast lasers. - - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - MIMAS - - - ERC-2014-ADG - - - 670557 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 251 857,80 - - - Higher-order interactions and Laplacian dynamics in complex networks: structure, dynamics and control - - - EUR 251 857,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Complex networks are an essential ingredient of modern life, and underpin integral parts of our biological, physical, technological and socio-economic universe. Thus far, such networks have been mainly represented as graphs. - However, while graphs can capture pairwise interactions between nodes, fundamental interactions in networks often take place between multiple nodes. For example, in socio-economic networks, the joint coordinated activity of several agents (e.g. - buyer, seller, broker); the formation and interactions of coalitions; the emergence of peer pressure; and the existence of triadic closure are all prevalent. - - 2020-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - HIntNets - - - H2020-MSCA-IF-2015 - - - 702410 - - - - - HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH - RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN - UNIVERSITE DE STRASBOURG - BOEHRINGER INGELHEIM PHARMA GMBH &CO KG - UNIVERSITA DEGLI STUDI DI MODENA E REGGIO EMILIA - ASTRAZENECA AB - Eidgenössische Technische Hochschule Zürich - UNIVERSITAET BERN - LEAD DISCOVERY CENTER GMBH - - - EUR 2 555 534,16 - - - Big Data in Chemistry - - - EUR 2 555 534,16 - - - Germany - Germany - France - Germany - Italy - Sweden - Switzerland - Switzerland - Germany - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The advent of the big data era in chemistry and the life sciences requires the development of new computational analysis methods, which are not only of scientific, but also economic relevance. Currently, the international data - market already grows six times faster than the entire IT sector, and growth rates further increase. Achieving and sustaining a leadership positions in the big data arena represent critically important challenges for the EU. The economic developments - in the emerging big data field are science-driven. Due to complexity and heterogeneity of biochemical and biomedical data, large-scale data exploration and exploitation are intrinsically interdisciplinary tasks. BIGCHEM positions itself at interfaces - between chemistry, computer science, and the life science to provide well-structured multidisciplinary training and educate high-in-demand computational specialists capable of operating in interdisciplinary and international research and business - settings. Cornerstones of BIGCHEM’s curriculum include on-line lectures and periodic schools taught by internationally leading experts in chemical and life science informatics, a balanced consortium of academia, SMEs, and large industry, and an - unprecedented symbiosis of academic and industrial training and application components. Accordingly, BIGCHEM is well positioned to boost multilateral collaborations between academia and industry and train scientists who are highly competitive in the - international big data market. In BIGCHEM’s R&D and training activities, the development and evaluation of conceptually novel methods for large-scale data analysis, knowledge extraction, and information sharing with demonstrated practical - application potential take center stage. The network has a clearly defined policy for exploitation of new IP through wide involvement of target users, SMEs, and large industry facilitated by the experienced technology transfer department of the - coordinator's team. - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-EID - Marie Skłodowska-Curie Innovative Training Networks (ITN-EID) - - - MSCA-ITN-EID - European Industrial Doctorates - - - Germany - - - BIGCHEM - - - H2020-MSCA-ITN-2015 - - - 676434 - - - - - UPPSALA UNIVERSITET - UPPSALA UNIVERSITET - - - EUR 1 738 690 - - - Integrating spatial and genetic information via automated image analysis and interactive visualization of tissue data - - - EUR 1 738 690 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Digital imaging of tissue samples and genetic analysis by next generation sequencing are two rapidly emerging fields in pathology. The exponential growth in digital imaging in pathology is catalyzed by more advanced imaging - hardware, comparable to the complete shift from analog to digital images that took place in radiology a couple of decades ago: Entire glass slides can be digitized at near the optical resolution limits in only a few minutes’ time, and fluorescence as - well as bright field stains can be imaged in parallel. - - - 2021-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Sweden - - - TissueMaps - - - ERC-2015-CoG - - - 682810 - - - - - KUNGLIGA TEKNISKA HOEGSKOLAN - KUNGLIGA TEKNISKA HOEGSKOLAN - - - EUR 2 097 520 - - - Flow physics and interaction of laminar-turbulent transition and flow separation studied by direct numerical simulations - - - EUR 2 097 520 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The vision spelled out in this proposal is to overcome the failure of Computational Fluid Dynamics to tackle one of the central unsolved fluid physics problems, namely predicting the sensitive flow physics associated with - laminar-turbulent transition and flow separation. A recent, highly influential report by NASA (Slotnick et al., 2014) clearly states that the major shortcoming of CFD is its “… inability to accurately and reliably predict turbulent flows with - significant regions of separation”, most often associated with laminar-turbulent transition. - - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Sweden - - - TRANSEP - - - ERC-2015-AdG - - - 694452 - - - - - QUEEN MARY UNIVERSITY OF LONDON - UNIVERSITEIT MAASTRICHT - UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - KAROLINSKA INSTITUTET - LIFEARC - - - EUR 2 887 041,24 - - - European Vascular Interventions and Therapeutic Innovation Network - - - EUR 2 887 041,24 - - - United Kingdom - Netherlands - Ireland - Germany - Sweden - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - EVOluTION, a pioneering network within EU in view of its focus on endogenous protective mechanisms, is formed to provide training for 11 young researchers in innovative therapeutic strategies, integrating early detection and - prevention, to yield novel approaches to the management of chronic vascular and metabolic diseases that affect the increasing ageing population of Western societies. Fully aligned with the knowledge triangle (business, research and higher education) - platform being developed at the EU level, EVOluTION-trained young scientists will gain valuable knowledge and multidisciplinary skills: only interdisciplinary and cross-cutting research can lead to novel therapeutic tools and scientific angles to - address these challenging medical, societal and industrial issues. - - - 2020-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - EVOluTION - - - H2020-MSCA-ITN-2015 - - - 675111 - - - - - UNIVERSITAET BERN - UNIVERSITAET BERN - - - EUR 2 255 788 - - - Deciphering the greenhouse gas record in deepest ice using continuous sublimation extraction / laser spectrometry - - - EUR 2 255 788 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The recent anthropogenic global warming makes a detailed understanding of coupling processes between climate and biogeochemical cycles of pressing importance. The atmospheric archive of air bubbles enclosed in polar ice cores - provides the only direct record of greenhouse gas changes in the past, and the key to understanding the related changes in biogeochemical cycles and climate/greenhouse gas feedbacks. - - - 2020-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Switzerland - - - deepSLice - - - ERC-2014-ADG - - - 667507 - - - - - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - TECHNISCHE UNIVERSITEIT DELFT - FRIEDRICH-SCHILLER-UNIVERSITAT JENA - KARLSRUHER INSTITUT FUER TECHNOLOGIE - HEPTAGON OY - SUSS MICROOPTICS SA - HOLOEYE PHOTONICS AG - CARL ZEISS AG - ASML NETHERLANDS B.V. - NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO - JCMWAVE GMBH - DATALOGIC IP TECH SRL - Meyer Burger Research AG - - - EUR 3 855 693,24 - - - Lossless Photon management – Optical design for manufacture at different length scales - - - EUR 3 855 693,24 - - - Switzerland - Netherlands - Germany - Germany - Finland - Switzerland - Germany - Germany - Netherlands - Netherlands - Germany - Italy - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The target of this project is to prepare and train future engineers for the design challenges and opportunities provided by modern optics technology. Such challenges include lossless photon management, modelling at the system, - components and feature level, and the link between design and technology. Today all optical designs are often perceived following different approaches, namely geometrical optics, physical optics and nano-photonics. Traditionally these approaches are - linked to the different lengths-scale that are important to the system. Starting from the entire system that is macroscopic and uses geometrical optics, over the miniaturized unit that is based on micro-optics and needs physical optics design, down - to the active nano-photonics entity that allows steering light truly at the nano-scale but which requires to be designed with rigorous methods that provide full wave solutions to the governing Maxwell’s equations. A design for manufacture of next - generation optical applications necessarily requires to bridge the gap between the different length scales and to consider the design at a holistic level. At the core are optical simulation models developed and used in the academic research and the - one used for optical designs in industry. Up to now, only the academic partners apply an integral approach to include micro- and nano-photonics in their simulations. Together with the industrial partners projects will be launched to promote the - academic developments in optical design and simulation over different length scales towards the industry. The industry will use the know-how to consolidate their expertise, expand their businesses, and occupy new fields of activities. For each - research subject, may it be nano-photonics, micro-optics or system engineering, a channel can be provided to access particular knowledge and/or stimulate collaborations. - - 2020-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-EID - Marie Skłodowska-Curie Innovative Training Networks (ITN-EID) - - - MSCA-ITN-EID - European Industrial Doctorates - - - Switzerland - - - NOLOSS - - - H2020-MSCA-ITN-2015 - - - 675745 - - - - - UPPSALA UNIVERSITET - UPPSALA UNIVERSITET - - - EUR 2 496 972 - - - The Violence Early-Warning System: Building a Scientific Foundation for Conflict Forecasting - - - EUR 2 496 972 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The challenges of preventing, mitigating, and adapting to large-scale political violence are daunting, particularly when violence escalates where it is not expected. Early-warning systems of sufficient quality and transparency - do not exist, limiting the ability of the international community to effectively assist affected populations. We propose to develop, test, and iteratively improve a pilot Violence Early-Warning System (ViEWS) that is rigorous, data-based, and - publicly available to researchers and the international community. This objective is challenging but feasible. The conflict research community has laid the ground for such a system through careful isolation of theoretically manageable sub-components - of complex phenomena, and concomitant systematic, disaggregated data collection efforts. A major innovation in the project is to integrate these isolated research programs into a theoretically and methodologically consistent forecasting system, by - means of dynamic simulation techniques in combination with Bayesian Model Averaging, and guided by continuous out-of-sample evaluation. This integration effort will not only allow an early-warning system of unprecedented scope and performance, but - also build theoretically informative bridges between numerous compartmentalized conflict research programs. Concentrating on theoretical and methodological development, the pilot will be limited in scope to Africa but be scalable. ViEWS will provide - early warnings for four forms of political violence: armed conflict involving states and rebel groups, armed conflict between non-state actors, violence against civilians, and forced population displacement, and apply these to specific actors, - sub-national geographical units, and countries. Led by Håvard Hegre, the system will leverage the data resources within the Uppsala Conflict Data program, the world-leading provider of conflict data, in combination with a strong team of highly - experienced conflict scholars. - - 2021-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Sweden - - - ViEWS - - - ERC-2015-AdG - - - 694640 - - - - - FONDAZIONE BRUNO KESSLER - A.P.E. RESEARCH SRL - CSEM CENTRE SUISSE D'ELECTRONIQUE ET DE MICROTECHNIQUE SA - RECHERCHE ET DEVELOPPEMENT - III-V LAB - SINGLE QUANTUM BV - UNIVERSITAET BERN - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - B.I. Stepanov Institute of Physics of the National Academy of Sciences of Belarus - LFOUNDRY SRL - - - EUR 3 925 921,75 - - - All Solid-State Super-Twinning Photon Microscope - - - EUR 3 939 516,25 - - - Italy - Italy - Switzerland - France - Netherlands - Switzerland - Switzerland - Belarus - Italy - - - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The goal of the project is to develop the technology foundation for an advanced optical microscope imaging at a resolution beyond the Rayleigh limit, which is set by the photon wavelength. The proposed microscope technique is - based on super-twinning photon states (N-partite entangled states) with the de Broglie wavelength equal to a fraction of the photon wavelength. Such microscopy technique will comprise building blocks for object illumination, capturing of scattered - twinning photons and data processing. Based on advanced group-III nitride and III-V alloy epitaxial growths and wafer processing techniques we will build the first solid-state emitter of highly entangled photon states, utilizing the cooperative - effect of Dicke superradiance (super-fluorescence) emission. Single-photon avalanche detector arrays with data pre-processing capabilities sufficient for capturing high-order field correlation functions of scattered twinning photons will be - developed. A dedicated data processing algorithm for extracting the image of an illuminated object from the statistics of scattered twinning photons will complement the hardware. The project goal is to demonstrate imaging at 42 nm spatial resolution - using 5-partite entangled photons at 420 nm wavelength. This quantum imaging technology will open the way for compact, portable, super-resolution microscope techniques, with no moving parts and no requirements to the optical properties of the sample. - - 2019-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-1-2014 - FET-Open research projects - - - RIA - Research and Innovation action - - - Italy - - - SUPERTWIN - - - H2020-FETOPEN-2014-2015-RIA - - - 686731 - - - - - UPPSALA UNIVERSITET - - - EUR 185 857,20 - - - Alphaviral Immunotherapy against Glioblastoma - - - EUR 185 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - Alphaviral Immunotherapy against Glioblastoma - - 2018-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - AVITAG - - - H2020-MSCA-IF-2015 - - - 707093 - - - - - UNIVERSITAT POLITECNICA DE VALENCIA - Centro Regionale Information Communication Technology scrl - POLITECNICO DI MILANO - SVEUCILISTE U ZAGREBU FAKULTET ELEKTROTEHNIKE I RACUNARSTVA - PRO DESIGN Electronic GmbH - THALES COMMUNICATIONS & SECURITY SAS - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - PHILIPS MEDICAL SYSTEMS NEDERLAND BV - EATON INDUSTRIES (FRANCE) SAS - - - EUR 5 801 820 - - - MANGO: exploring Manycore Architectures for Next-GeneratiOn HPC systems - - - EUR 5 801 820 - - - Spain - Italy - Italy - Croatia - Germany - France - Switzerland - Netherlands - France - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - MANGO targets to achieve extreme resource efficiency in future QoS-sensitive HPC through ambitious cross-boundary architecture exploration for performance/power/predictability (PPP) based on the definition of new-generation - high-performance, power-efficient, heterogeneous architectures with native mechanisms for isolation and quality-of-service, and an innovative two-phase passive cooling system. Its disruptive approach will involve many interrelated mechanisms at - various architectural levels, including heterogeneous computing cores, memory architectures, interconnects, run-time resource management, power monitoring and cooling, to the programming models. The system architecture will be inherently - heterogeneous as an enabler for efficiency and application-based customization, where general-purpose compute nodes (GN) are intertwined with heterogeneous acceleration nodes (HN), linked by an across-boundary homogeneous interconnect. It will - provide guarantees for predictability, bandwidth and latency for the whole HN node infrastructure, allowing dynamic adaptation to applications. MANGO will develop a toolset for PPP and explore holistic pro-active thermal and power management for - energy optimization including chip, board and rack cooling levels, creating a hitherto inexistent link between HW and SW effects at all layers. Project will build an effective large-scale emulation platform. The architecture will be validated through - noticeable examples of application with QoS and high-performance requirements. - - 2018-09-30, ongoing project | - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.2."> - - - FETHPC-1-2014 - HPC Core Technologies, Programming Environments and Algorithms for Extreme Parallelism and Extreme Data Applications - - - RIA - Research and Innovation action - - - Spain - - - MANGO - - - H2020-FETHPC-2014 - - - 671668 - - - - - UNIVERSITAET BERN - - - EUR 187 419,60 - - - Associational resistance and neighbor recognition of in common dandelion roots - - - EUR 187 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - Plants are able to recognize the chemical cues from neighbors and modulate their investment into growth and defense accordingly. While the effects and mechanisms of neighbor recognition on above ground plant-herbivore - interactions have been studied extensively, they have rarely been investigated below ground, despite the importance of root herbivores and root-root signaling. The key objectives of DARES are 1) to investigate how does the presence of conspecific and - heterospecific neighbors affects the root metabolism and defenses of Taraxacum officinale and its resistance against its main natural enemy, the white grub Melolontha melolotha, 2) to identify the type of chemical information that T. officinale uses - to recognize neighbors (above ground volatiles, below ground volatiles or root exudates), and 3) to identify the chemical compounds from neighboring plants that T. officinale responds to. The results of DARES will allow me to assess the importance of - associational resistance for below ground interactions. Furthermore, the gained knowledge will help to employ plant-based control strategies of T. officinale as a weed and M. melolontha as a grassland pest. - - 2018-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - DARES - - - H2020-MSCA-IF-2015 - - - 704334 - - - - - KARLSRUHER INSTITUT FUER TECHNOLOGIE - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - DANMARKS TEKNISKE UNIVERSITET - KEMIJSKI INSTITUT - UPPSALA UNIVERSITET - - - EUR 4 114 753,50 - - - A new class of powerful materials for electrochemical energy storage: Lithium-rich oxyfluorides with cubic dense packing - - - EUR 4 114 753,75 - - - Germany - France - Denmark - Slovenia - Sweden - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - - The LiRichFCC project will explore an entirely new class of materials for electrochemical energy storage termed “Li-rich FCC” comprising a very high concentration of lithium in a cubic dense packed structure (FCC). The process - by which energy is stored in these materials constitutes a paradigm change in the design of battery materials and involves unexpected and surprisingly effective mechanisms: instead of storing lithium ions by intercalation into a stable host, lithium - ions are populating and vacating lattice sites of the material itself. This new principle allows for unprecedented energy and power density compared to other battery materials and may revolutionize the use of batteries in applications involving a - need for supplying large amounts of energy and power from small spaces. - - 2019-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-1-2014 - FET-Open research projects - - - RIA - Research and Innovation action - - - Germany - - - LiRichFCC - - - H2020-FETOPEN-2014-2015-RIA - - - 711792 - - - - - ECOLE DES HAUTES ETUDES EN SCIENCES SOCIALES - - - EUR 201 024 - - - Violent settlements: strategic villages and clandestine burial sites in Latin America - - - EUR 201 024 - - - France - - - Higher or Secondary Education Establishments - - In contemporary warfare the power to destroy cities exists alongside with the power to built urban places ex nihilo. In the 70s and 80s, various Latin American States forcedly displaced people to villages created as an - instrument of counterinsurgency; at the same time massacres and forced disappearances occurred in these regions. How does the simultaneous creation of strategic villages and clandestine burial sites affect the ways of inhabiting and imagining space - in the aftermath of political violence? My study aims at analysing for the first time the connexion between mass violence and the forced creation of built environment. Based on qualitative fieldwork undertaken in Tucumán (Argentina) and Ayacucho - (Peru) and framed within social anthropology, sociology and human geography, this research will produce a seminal in-depth study of the daily life among the strategic villages in Latin America, by analysing the experience of subjects that were forced - to inhabit there. - - 2019-01-31, ongoing project - - - 2016-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - France - - - StrategicVillages - - - H2020-MSCA-IF-2014 - - - 654923 - - - - - CARDIFF UNIVERSITY - - - EUR 267 147 - - - Southern Ocean and Antarctic Climatic Phasing:Tephrochronological Correlation of Southern Ocean Marine Records and Antarctic Ice-cores - - - EUR 267 147 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Determining the temporal relationships of large-scale atmospheric and oceanic fluctuations is crucial for advancing understanding of the mechanisms controlling heat transfer between the Northern and Southern Hemispheres. The - thermal bipolar see-saw caused asynchronous interhemispheric climatic changes during the last glacial period and Southern Ocean marine records and the Antarctic ice-cores are valuable archives recording this past climatic variability. Ascertaining - the precise phasing of the climatic variability between these records provides crucial boundary conditions for testing models simulating the future behaviour of the bipolar see-saw and assessing potential large-scale oceanic and atmospheric - reorganisations under anthropogenic forcing. In addition, establishing tighter constraints on phase relationships between sedimentary evidence for deep-water ventilation of CO2, and ice-core evidence for past atmospheric CO2 variations is key to - determining the future response of the Earth system to rising CO2 levels. This project will address this challenge by ascertaining the rate, timing and phasing of Southern Hemisphere climatic changes between 40-10 kyr BP using tephrochronology to - independently synchronise the palaeoclimatic sequences using common horizons of volcanic ash as time-synchronous tie-lines. Recognition of ash horizons not visible upon core inspection (cryptotephras) within sequences increasingly distal from - volcanic regions has increased the scope of this technique. Cryptotephra identification methods will be used to trace ash horizons visible in Antarctic ice-cores into a marine core network from the Southern Ocean Atlantic sector and to trace - previously unknown horizons identified in the marine realm into the Antarctic Atlantic sector EPICA DML ice-core. This region has a high potential for synchronisation due to the number of upwind volcanic regions that have previously deposited - volcanic ash over the ice-sheet and Southern Ocean. - - 2019-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - SHARP - - - H2020-MSCA-IF-2014 - - - 656381 - - - - - SVEUCILISTE U ZAGREBU, FAKULTET STROJARSTVA I BRODOGRADNJE - - - EUR 158 010 - - - Structured Training and Advanced Research in Marine Active Structures - - - EUR 158 010 - - - Croatia - - - Higher or Secondary Education Establishments - - In the last 25 years the total amount of marine trade has nearly doubled. In the same period the container trade has undergone a tenfold increase, making the container fleet the fastest growing fleet at present. With 80% of - total EU trade being transported by sea, the maritime transport is of the greatest importance to the EU. The increasing demand in container transportation is met by use of more containerships. Such ships with large bow and stern flares and fine - underwater hull are severely hit by an effect known as parametric rolling. Accidents including container loss and vessel structural damage are reported from all around the world. Capsizing could be regarded as a rare event, but the consequences of - such event are fatal (loss of the ship and the crew). Agencies, classification societies and the public are showing more and more interests in increasing the safety of large container ships. STARMAS is a highly interdisciplinary integrated research - and training programme focused on the application of novel active control methods to increase safety, energy efficiency and quality of life at sea of the 21st century maritime transport. The problem of ship roll on rough seas will be tackled using - novel active roll control methodologies. Bi-directional transfer of knowledge and cross-fertilisation between traditionally detached engineering disciplines will be unlocked, utilising a unique research approach to enduring engineering problems - related to sea keeping, survival rate, and energy efficiency of marine vessels. The programme will boost the career prospects, increase employability and widen the set of skills of the experienced researcher. The training and research will - predominately take place within the academic sector, at the Faculty of Mechanical Engineering and Naval Architecture (FAMENA). The researcher will also benefit from secondments to the non-academic partner Bureau Veritas, Paris, (BV) facilitating an - inter-sectoral transfer of knowledge. - - 2018-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Croatia - - - STARMAS - - - H2020-MSCA-IF-2014 - - - 657539 - - - - - ASTON UNIVERSITY - ALCATEL-LUCENT DEUTSCHLAND AG - DANMARKS TEKNISKE UNIVERSITET - INSTITUT MINES-TELECOM - TECHNISCHE UNIVERSITEIT DELFT - - - EUR 1 081 619,64 - - - Fibre optic nonlinear technologies - - - EUR 1 081 619,64 - - - United Kingdom - Germany - Denmark - France - Netherlands - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Fibre-optic communication systems form the backbone of the world’s communication infrastructure as they provide for lion fraction (more than 99%) of the global data traffic. The ongoing exponential growth in network traffic, - however, is pushing current technology, whose data rates had increased over several decades, towards its limits. It is widely accepted that the nonlinear transmission effects in optical fibre are now a major limiting factor in modern fibre-optic - communication systems. Nonlinear properties of the optical fibre medium limit the conventional techniques to increase capacity by simply increasing signal power. Most of the transmission technologies utilized today have been originally developed for - linear (wired or wireless) communication channels. Over the past several decades, significant improvements in data rates were obtained by improvements and modifications within the overall linear transmission paradigm. However, there is much evidence - that this trend is going to end within the next decade due to fibre nonlinearity. There is a clear need for radically different approaches to the coding, transmission, and processing of information that take the nonlinear properties of the optical - fibre into account. This also requires education and training of a new generation of optical communication engineers and specialists with knowledge on nonlinear methods and techniques. - - - 2022-05-31, Grant Agreement signed - - - 2018-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-EID - European Industrial Doctorates - - - United Kingdom - - - FONTE - - - H2020-MSCA-ITN-2017 - - - 766115 - - - - - WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER - UNIVERSITE DE REIMS CHAMPAGNE-ARDENNE - UNIVERSITA DEGLI STUDI DELL'INSUBRIA - PANEPISTIMIO PATRON - UPPSALA UNIVERSITET - "NATIONAL CENTER FOR SCIENTIFIC RESEARCH ""DEMOKRITOS""" - SEREND-IP GMBH - FIDIA FARMACEUTICI SPA - SEMMELWEIS EGYETEM - - - EUR 567 000 - - - Matrix glycans as multifunctional pathogenesis factors and therapeutic targets in cancer - - - EUR 567 000 - - - Germany - France - Italy - Greece - Sweden - Greece - Germany - Italy - Hungary - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - Cancer is a leading cause of mortality within the aging European population. Therapeutic targeting is hampered by the complexity of the disease, which includes not only molecular changes within the tumor cell itself, but also - within its microenvironment. Tumor angiogenesis, tumor-stroma interactions, interactions with immune cells, with the extracellular matrix and cancer stem cell niches allow for malignant cell survival and promote metastasis, the leading cause for - cancer-associated mortality. Proteoglycans (PGs) and glycosaminoglycans (GAGs) – structurally diverse carbohydrates of the extracellular matrix and cell surfaces - have emerged as novel biomarkers and molecular players both within tumor cells and - their microenvironment, as they integrate signals from growth factors, chemokines and integrins, and cell-cell as well as matrix adhesion. Importantly, their expression is dysregulated in numerous tumor entities, and has been shown to modulate each - of the hallmarks of cancer as defined by Hanahan and Weinberg (Cell 2011). We hypothesize that dysregulated function of PGs and GAGs simultaneously affects all molecular steps towards cancer metastasis as a general principle applicable to multiple - tumor entities. Pharmacological modulation of their function thus emerges as an attractive multitargeted antitumoral approach which simultaneously acts at multiple levels of disease progression. Besides providing extensive knowledge transfer and - training for researchers, the combined expertise of the GLYCANC consortium aims at performing a detailed structural analysis of PG and GAG glycans in disease using state-of-the art methodology, analysing their regulation via epigenetic mechanisms and - microRNAs, and elucidating molecular mechanisms underlying aberrant PG and GAG function. GLYCANC will lead to a deeper understanding of glycan structures and glycan-dependent mechanisms promoting cancer progression, providing the basis for rational - multitargeted anticancer approaches. - - 2019-06-30, ongoing project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Germany - - - GLYCANC - - - H2020-MSCA-RISE-2014 - - - 645756 - - - - - UNIVERSITAET BERN - - - EUR 187 419,60 - - - The Effects of Media News about Immigrants on Majority’s Attitudes and Behaviors towards Immigrants - - - EUR 187 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - The interdisciplinary IMMIGRANTS project aims at a better understanding of how media influence majority’s attitudes and behaviors towards immigrants – a socially pressing issue connected to rapid expansion of immigration in - Europe. In the project, I will focus on different aspects of media news – their valence, labels used for immigrants’ ethnicity and pictures of immigrants accompanying media articles about immigrants. The first goal of my research is to investigate - how different labels used for immigrants’ ethnicity (nouns vs. adjectives) combined with different valence of media articles about immigrants (positive vs. negative vs. ambivalent) influence participants’ attitudes and behaviors towards immigrants. - My second goal is to compare the effects of articles accompanied by different images of immigrants and articles without such images on participants’ attitudes and behaviors towards immigrants. Both goals feature a number of tasks related to the - effects of media articles on attitudes and behaviors towards immigrants: I will test underlying mechanisms (e.g., biometrically tracked positive and negative emotions) and boundary conditions (e.g., social status and category salience of an immigrant - group, participants’ intergroup contact with immigrants) of these effects. In three studies of the IMMIGRANTS project, I bring together different traditions on media and immigrant research and address several gaps in social scientific literature - (e.g., too narrow focus on negative media news in political and media research, too narrow focus on positive intergroup contact and self-reported emotions in psychology). The outcome of IMMIGRANTS can be used to inform guidelines for professional - training of journalists, policy makers, and social workers to become more sensitive to the impact of language describing immigrants. - - 2018-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - IMMIGRANTS - - - H2020-MSCA-IF-2015 - - - 703495 - - - - - FREIE UNIVERSITAET BERLIN - - - EUR 171 460,80 - - - Certifying Large-scale Quantum Information Technologies - - - EUR 171 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - Our modern society and economy depend upon the constant, high-speed transmission and processing of information. Since every instance of computation or communication is realised by some physical device, it is the laws of - physics that set the ultimate limits on performance. Applying this reasoning to quantum theory has led to a plethora of algorithms and protocols that achieve previously impossible levels of computational power and security. Realising the full promise - of quantum information technologies will require theoretical tools, tailor-made to specific applications, which quantify the performance of a given protocol in a manner that is practical, efficient and satisfying to a sceptical end-user. This problem - is particularly pressing in systems that admit a formal description only in terms of infinite dimensions. Experimental progress in such systems has shown them to be extremely promising as quantum technology platforms, but the technical difficulties - in the analysis have severely constrained their application for cryptographic and information processing applications. - - 2020-05-31, Grant Agreement signed - - - 2018-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - CerQUIT - - - H2020-MSCA-IF-2016 - - - 750905 - - - - - ECOLE DES HAUTES ETUDES EN SCIENCES SOCIALES - FREIE UNIVERSITAET BERLIN - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 778 500 - - - Understanding institutional change in Asia: a comparative perspective with Europe - - - EUR 778 500 - - - France - Germany - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The project INCAS aims at creating a top-level research and advanced training network on institutional change in Asia, in comparative perspective with Europe. The coordinator, Ecole des Hautes Etudes en Sciences Sociales - (France), promotes this network together with Oxford University, Freie Universität Berlin, in collaboration with Waseda University (Japan). The partners have chosen Japan as a reference point because of its comparability with Europe as shown by - previous studies, its historical influence on development and further institutional changes in Asia, and the expertise accumulated within our research team. - - 2019-05-31, ongoing project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - France - - - INCAS - - - H2020-MSCA-RISE-2014 - - - 645763 - - - - - UNIVERSITAT ROVIRA I VIRGILI - TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY - INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU METALE NEFEROASE SIRARE-IMNR - POLITECHNIKA GDANSKA - UNIVERSITAET ULM - MOLECULAR FINGERPRINT SWEDEN AB - SITEX 45 SRL - JLM INNOVATION GMBH - UNIWERSYTECKIE CENTRUM MEDYCYNY MORSKIEJ I TROPIKALNEJ - - - EUR 1 386 000 - - - Development of a non-invassive breath test for early diagnosis of tropical diseases - - - EUR 1 386 000 - - - Spain - Israel - Romania - Poland - Germany - Sweden - Romania - Germany - Poland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - This project aims at demonstrating the feasibility of a non-invasive, safe and patient-friendly methodology for on-site rapid diagnosis of tropical diseases. The proposed approach is based on breath samples analyses, which are - easy to obtain and present no discomfort or risk for patients health. In this study will be enrolled patients with three different types of neglected tropical diseases (Hydatidosis, Leishmaniasis and Dengue) from different geographical locations - (Europe, South America and Maghreb). Breath sampling will follow a standardised procedure. Analytical chemistry methods will be employed for the identification of the breath volatile biomarkers of these diseases. A pool of potential nanomaterials - with high affinity towards the identified VOCs will be selected (e.g., gold nanoparticles, carbon nanotubes and semiconducting nanowires, either pristine or functionalised with selected hydrophobic organic molecules and/or bio-molecules). For - maximising the possibility of success of our methodology, we will investigate the synergic effect of different advanced and complementary chemical sensing techniques: Mid-Infrared Quantum Cascade Laser spectroscopy and different types of Chemical Gas - Sensors devices. These techniques are particularly attractive, since they can be miniaturised and are suitable for building on-site portable systems. Advanced pattern recognition algorithms will be employed for building discriminative models for the - identification of the fingerprints of the different tropical diseases studied, and multisensors data fusion will be then applied for obtaining enhanced results. A point of care prototype will be proposed on the basis of the results obtained and - validated on-site. - - 2019-01-31, ongoing project - - - 2015-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Spain - - - TROPSENSE - - - H2020-MSCA-RISE-2014 - - - 645758 - - - - - SYDDANSK UNIVERSITET - - - EUR 200 194,80 - - - Breaking the Ice: INGOs as Arctic Council Observer Status Applicants - - - EUR 200 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - In international politics, the Arctic has emerged as one of the hottest geo-political arenas for international non-governmental organization (INGO) work in the 21st century. One of the big attractions for INGOs has been the - leading regional forum, the Arctic Council, which has integrated a way for INGOs to be included into Arctic regional environmental protection and economic development discussions. This role is called ‘observer status’ and INGOs can apply for, and - potentially obtain, observer status within the forum which gives them some degree of access to political discussions as they are unfolding and the political and bureaucratic elite operating on the front line of regional discussions and treaties. - - - 2020-02-29, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - ACOSA - - - H2020-MSCA-IF-2016 - - - 746312 - - - - - FRIEDRICH-SCHILLER-UNIVERSITAT JENA - CCKF Ltd - TECHNOLOGIKO PANEPISTIMIO KYPROU - 3S UNTERNEHMENSBERATUNG GMBH - - - EUR 679 500 - - - Transforming European Women’s Entrepreneurship: The Education and Training for Success Programme - - - EUR 679 500 - - - Germany - Ireland - Cyprus - Austria - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The objective of the women entrepreneurs project is to set up and strengthen international and inter-sectoral collaboration in the research field of competence development in young women entrepreneurs and to promote women’s - entrepreneurial potential in Europe. - - - 2019-02-28, ongoing project | - - - 2015-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Germany - - - women entrepreneurs - - - H2020-MSCA-RISE-2014 - - - 645441 - - - - - FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA - - - EUR 158 121,60 - - - Mechanobiology of the cellular circadian clock - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - The circadian clock is the biological mechanism that directs the physiological ~24 hour oscillations that most living organisms undergo to anticipate the daily pattern of light. In mammals, that rhythmicity results from a - highly conserved genetic circuit –based on transcriptional and post-transcriptional regulation– that works synchronously at a cellular level and differs among tissues. Around the 10% of the mammalian proteins, including essential components of the - cell cycle and differentiation pathways have been categorised as circadian. Thus, a clock dysregulation may have pathological consequences, which is the case in some types of cancer. - - - 2020-06-30, Grant Agreement signed - - - 2018-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - MECHADIAN - - - H2020-MSCA-IF-2016 - - - 750557 - - - - - UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA - - - EUR 257 191,20 - - - Developing Smart 3D Scaffolds based on Conductive Polymers and Carbon Nanotubes for Cardiac Tissue Engineering - - - EUR 257 191,20 - - - Spain - - - Higher or Secondary Education Establishments - - Conductive polymers (CP) appear as promising stimulus-responsing electroactive biomaterial for profileration of cells. CP are versatile materials that can be synthesized in different shapes and morphologies, offering a wide - range of application in biosensing, implants, drug delivery and tissue engineering. Carbon Nanotubes (CNTs) have become promising advanced materials and gained increasing importance for applications in nanomedicine, such as diagnosis, disease - treatment, imaging, and tissue engineering. CNTs can interact with cells, cross the biological barriers, and modify their functions and biology. More recently, CNTs have become a new tool to specifically interact with the central nervous systems and - support tissue repair after brain damage. Take into account of such findings, we hypothesize that CNTs exert functional effects on networks of cardiac myocytes and, in addition, the combination of those two materials will generate an outstanding - scaffold for other electroactive cell growth, such as cardiac cells. In my current research, I have developed 3D scaffolds of CNT with a CP skeleton (polypyrrole or PEDOT) and, aftewards, the goal of my research and thus the aim of the current - proposal is to test such scaffolds for cardiac tissue regeneration. More specific aims are: - - - 2021-04-30, Grant Agreement signed - - - 2018-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Spain - - - NanoBeat - - - H2020-MSCA-IF-2016 - - - 753293 - - - - - INSTITUT POLYTECHNIQUE DE GRENOBLE - - - EUR 123 384 - - - Deep understanding and modelling of the hierarchical structure of Prosody - - - EUR 123 384 - - - France - - - Higher or Secondary Education Establishments - - The prime objective of the ProsoDeep project is to gain a deeper understanding of the language of prosody through the analysis of all the levels in the production hierarchy of prosody. In particular, it will exploit the - benefits of the top-down and bottom-up approaches through their incorporation within a Deep Prosody Model (DPM). The DPM will facilitate the advancement of speech technologies that rely both on the synthesis of prosody, e.g. text-to-speech (TTS) - systems, and its analysis, e.g. speech emotion recognition (SER). To reach this objective the project will draw on a variety of scientific fields, including signal processing, physiology of prosody production and biomechanics, linguistics, and - machine learning, and will also be augmented with respiratory measurements. - - 2019-01-17, ongoing project - - - 2017-09-18 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - ProsoDeep - - - H2020-MSCA-IF-2016 - - - 745802 - - - - - UNIVERSITEIT LEIDEN - - - EUR 177 598,80 - - - Detection of bio-signatures in space research using a new and innovative measurement technique based on laser desorption ionisation mass spectrometry - - - EUR 177 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Detection of bio-signatures on planetary objects are of high interest for science and society. Mars is one of the most promising target in our Solar System to find traces of life. Several missions are planned in the future by, - e.g., NASA and ESA to find bio-signatures on Mars. Unfortunately, since the first Viking landing on Mars in the 1970s the quest for finding bio-signatures remains unresolved. Therefore, the development of new measurement concepts for the detection of - bio-signatures is of high importance for future space missions to Mars. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - BioTec - - - H2020-MSCA-IF-2016 - - - 750353 - - - - - FRIEDRICH-SCHILLER-UNIVERSITAT JENA - - - EUR 159 460,80 - - - Exciton-Phonon Coupling from First Principles - - - EUR 159 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - Optical properties of materials are most relevant for a large variety of technological applications, ranging from photovoltaics over various spectroscopy techniques to LEDs and displays. In optical spectra, microscopic quantum - many-body effects like excitons, i.e. coupled electron-hole-pair excitations, are measurable at a macroscopic scale and crucially determine the materials properties. Hence, a deep understanding of excitons constitutes an indispensable driving force - for innovation in optics and optoelectronics. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - EXPHON - - - H2020-MSCA-IF-2016 - - - 751823 - - - - - AARHUS UNIVERSITET - - - EUR 212 194,80 - - - Photonic-assisted Neuromorphic Computing system - - - EUR 212 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - Neuromorphic computing has emerged as a promising approach to mimic the brain by overcoming the limitation of the conventional computers. The current implementation of neuromorphic computing systems (NCSs) has been done in - CMOS technology, which comes with area and power-inefficiency. Enormous effort has been devoted to optimize the area and power-efficiency of such NCSs. One of the most promising approaches is the implementation of NCSs using spin-based devices - combined with electronics (i.e. spintronics). Although, power-density is improved by spintronics-based NCSs, they are still far from the power-density of the brain that is attributed to the traditional way of changing the state of magnetic moment - using a bias current that contributes to 90% of the total power consumed by such NCSs. Given a technique eliminating or decreasing this bias current, the power density of NCSs can be improved by orders of magnitude. - - - 2019-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - PHOTON-NeuroCom - - - H2020-MSCA-IF-2016 - - - 751089 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 170 121,60 - - - Superlattices and proximity effects in 2D materials/molecules hybrid van der Waals heterostructures - - - EUR 170 121,60 - - - Spain - - - Research Organisations - - Van der Waals heterostructures, in which graphene and related 2D materials are mechanically superimposed in a stacked structure, represent a versatile platform to obtain materials with unique properties. These - artificially-assembled materials will revolutionize a number of research fields directly linked to applications, such as information and communication, and ultimately everyday life. In this context, molecules are particularly attractive, since the - almost-unlimited degrees of freedom in chemical design offer the possibility to confer ad-hoc functionalities to 2D materials, paving the way to novel and unexplored areas of physics and materials science. - - 2019-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - SUPER2D - - - H2020-MSCA-IF-2016 - - - 748971 - - - - - UNIVERSITETET I BERGEN - - - EUR 208 400,40 - - - Enhancing Seafood Ethics and Sustainability: A Values and Ecosystem-based Management Approach - - - EUR 208 400,40 - - - Norway - - - Higher or Secondary Education Establishments - - This project aims to explore new ways of securing seafood sustainability by embedding ethics and values in the management framework. In resource management and governance the explicit articulation of values is missing. Values - can aid decision-makers in resolving inherent policy trade-offs that emerge at the science-policy nexus. This will facilitate more transparent, accountable, and inclusive public decision-making. eSEAS’ objectives are threefold: a. to promote - cutting-edge, interdisciplinary research in the nascent field of seafood ethics; b. to develop three innovative multidisciplinary “fit-for-purpose” decision-support tools to enhance seafood ethics and sustainability; and c. to implement ethical - approaches to European management challenges, including the complex multijurisdictional Norwegian-spring spawning and North Sea herring fisheries. The eSEAS action consists of five integrated research and training activities: 1. to define seafood - ethics in relation to marine resource sustainability, policy, and governance within a post-normal science approach; 2. to develop an integrated ethical triage approach to assess sustainability with ethical indicators and test it for the balanced - harvesting approach; 3. to conduct value chain analyses of European case studies, in response to consumer demand for ethical seafood; 4. to refine the values- and ecosystem-based management approach (VEBMA) I developed by incorporating a robust - knowledge quality assessment and a game-theoretical / agent-based modelling approach to search for stable equilibria given stakeholder preferences; and 5. to introduce an ethical approach and apply aspects of the refined VEBMA to the NSS and North - Sea herring fisheries management at ICES participatory workshops. Through public engagement and dissemination, eSEAS will catalyze a science-society dialogue and collective actions to enhance seafood ethics and sustainability. - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Norway - - - eSEAS - - - H2020-MSCA-IF-2016 - - - 753937 - - - - - UNIVERSITAET BERN - BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE - - - EUR 247 840,20 - - - Patient-specific tumour growth model for quantification of mechanical 'markers' in malignant gliomas: Implications for treatment outcomes. - - - EUR 247 840,20 - - - Switzerland - United States - - - Higher or Secondary Education Establishments - Other - - Gliomas are the most frequent primary brain tumours in adults (70%) with Glioblastoma multiforme (GBM) being the most frequent and most malignant sub-type (about 50%). Their growth is characterised by infiltration of - surrounding healthy tissue, rapid proliferation, and the formation of a necrotic core. GBM growth often creates biomechanical forces that cause compression and displacement of the surrounding brain tissue. This mass-effect is of direct clinical - importance; it correlates to functional loss and pressure-induced brain herniation is the leading cause of death for 73% of patients, however this is not used to inform treament. Overall long term prognosis for GBM remains poor, with median - overall-survival below 1.5 years and 5-y survival rates below 3%. - - 2020-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Switzerland - - - GlimS - - - H2020-MSCA-IF-2016 - - - 753878 - - - - - MOSAIQUES DIAGNOSTICS GMBH - - - EUR 159 460,80 - - - Molecular profiling of Bladder Cancer to support personalized medicine - - - EUR 159 460,80 - - - Germany - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - BioMedBC Proposal is focused on improving the patient management of Bladder Cancer (BC). BC presents with the highest recurrence rate and the highest associated costs of all cancers. Due to the intrinsic heterogeneity, the - investigated drugs in clinical trials, cannot be easily introduced in the clinical practice. Molecular profiles/ biomarkers (BM) with predictive potential are required to enable patient stratification. The BioMedBC proposal aims at the application of - systems biology and cross-omics data integration methodologies to achieve: a) the molecular characterization of BC and b) develop signatures to predict the clinical outcome. To achieve these goals, integration of: i) high resolution proteomics - datasets (planned to be acquired within BioMedBC), ii) existing datasets that were obtained in previous EU collaborative projects and iii) publicly available transcriptomics data, will be conducted, focusing on the molecular characterization of BC. - Emphasis is given on the investigation of disease prognosis. For this purpose, clinical and follow-up data, available from ongoing prospective studies (n=1758), will be utilized for correlation analysis of the molecular profiles/ biomarkers with - disease outcome (recurrence, progression and survival). The prognostic value will be confirmed in newly collected samples with emphasis placed on urinary protein/ peptide profiles, as non-invasive urinary markers is of significant added value. The - innovation is held on the prognostic BM that can be further used to stratify patients to those that could be benefited by a potential intervention and guide personalized therapy to improve BC patient management. In parallel, BioMedBC aims at - expanding upon the current training of the ER, Dr. Maria Frantzi, on transferability of the basic research results to clinically useful products and create strong career prospects for her desired development as an owner of a future SME. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-SE - Society and Enterprise panel - - - Germany - - - BioMedBC - - - H2020-MSCA-IF-2016 - - - 752755 - - - - - UNIVERSITAET BERN - - - EUR 187 419,60 - - - Dissecting Rho GTPase signalling networks through acute perturbation techniques - - - EUR 187 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - Recent advances in technologies to measure Rho GTPase signaling with unprecedented spatiotemporal resolution in single living cells have led to novel questions. Important new insights are that Rho GTPase signaling involves the - formation of signaling complexes that fluctuate on subminute time and micrometer length scales, and that complex signaling networks involving multiple Rho GTPases fine tune the leading edge dynamics that power fibroblast migration. Novel - methodologies are required to dissect this newly discovered signaling complexity. RhoSNATCH aims to characterize these signaling networks by acutely perturbing and recording Rho GTPase signaling at biologically relevant timescales in live-cell - imaging experiments of cell migration. I will identify the crosstalk between Rac1/RhoA/Cdc42 that positions and maintains specific Rho GTPase activity zones in time and space and identify dedicated functional signaling modules that fine tune specific - cytoskeletal output at the leading edge of motile fibroblasts. - - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - RhoSNATCH - - - H2020-MSCA-IF-2016 - - - 747242 - - - - - FRIEDRICH-SCHILLER-UNIVERSITAT JENA - - - EUR 171 460,80 - - - “Thinking in Images. Herder’s Adrastea from 1801-03 up to nowadays” - - - EUR 171 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - The research project “Thinking in Images. Herder’s Adrastea from 1801-03 up to today” will focus on the notion of thinking in images, which has a non-marginal position in the history of philosophy and science. Thinking in - images means to refer, at the same time, to a complex system of forms and meanings, which continually changes itself and never follows a time sequence or a causal order. This is what distinguishes this special form of thinking from the logical - sequence, from the reasoning by concepts. Analogies, metaphors, myths are only few examples of the way this ‘visual representation’ works. Such a kind of thinking characterises the children’s thought, mnemonic processes, dreams, mental illnesses, - hallucinations; but also, it is possible to find it in the poetry, in mythologies and religions, in mystical visions, as well as in scientific visualisations and in the arts. We will try in this study to clarify the concept of thinking in images and - to highlight its value within society and culture. The starting point of the research is one of the most significant authors in the history of philosophy and culture, J.G. HERDER (1744-1803). The researcher’s aim will be to make an Italian - translation and a critical edition of the Adrastea (1801-1803), the last and most neglected of HERDER’s works. The researcher will show the importance of this work as regards the author’s position about this topic, thinking in images and will prepare - a monography. HERDER edited this magazine the last years of his life and conceived it as a kind of fragmentary encyclopaedia, touching many aspects of the cultural life of his time (from politics to religion, from philosophy to science, from - literature and music to esotericism and mystics). From this starting point, researcher will be able to start a multidisciplinary discussion on the topic through the organisation of seminars, workshop and international conferences with the involvement - of scholars of different fields of research. - - 2019-03-14, ongoing project - - - 2017-03-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - Germany - - - TIM-Adrastea - - - H2020-MSCA-IF-2016 - - - 753540 - - - - - THE MANCHESTER METROPOLITAN UNIVERSITY - - - EUR 195 454,80 - - - Multi-modal Approaches for Treatment and Evaluation of Swallowing Insufficiencies - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Human survival is dependent on swallowing because it underpins oral nutrition (eating/drinking) and protection of the respiratory tract. Swallowing difficulties (dysphagia) are a common consequence of a wide range of disorders - (eg. stroke, head & neck cancers, ageing) with the results (dehydration/malnutrition/weight loss/increased susceptibility to pneumonia) linked to significant decline in quality of life. There is significant need to improve diagnosis, monitoring - and rehabilitation (eg. by developing novel stimulation devices). However, existing gaps in understanding of the co-ordination of muscle activity significantly limit current advances. - - 2020-08-19, Grant Agreement signed - - - 2018-08-20 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - MATESI - - - H2020-MSCA-IF-2016 - - - 749978 - - - - - UNIVERSITAET BERN - - - EUR 175 419,60 - - - Exploiting carbohydrate/N-heterocyclic carbene hybrid complexes as innovative multifunctional oxidation catalysts with tailoring of weak interactions allowing for development of enzyme mimics - - - EUR 175 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - The key objective of this project is the development of innovative hybrid complexes for oxidative catalysis of pharmaceutically relevant functional groups (e.g. alcohols, amines, olefins), by combining the beneficial - properties of triazolylidine N-heterocyclic carbenes and carbohydrates for synergistic catalysis and molecular recognition, ensuring site-specific bind making and breaking processes and tailored delivery. A range of novel carbohydrate-functionalised - NHC complexes (e.g. with Ru(II) and Ir(III)) will be synthesised for these purposes and relationships between carbohydrate structure/geometry and catalytic activity probed, complementing experimental approaches with computational insight. - - 2019-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - GLYCONHC - - - H2020-MSCA-IF-2016 - - - 749549 - - - - - ECOLE NORMALE SUPERIEURE - ECOLE NORMALE SUPERIEURE - - - EUR 149 780 - - - BabyMinder: Automatic diagnosis of neurocognitive impairment in infants - - - EUR 149 780 - - - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Each year, millions of infants are born with neurodevelopment disorders resulting in cognitive deficits. Although infants are tested for their low-level (visual and auditory) abilities in the health care system, no standard - tools exist for evaluating the development of cognitive functions, due to the absence of verbal report and explicit behaviour. Converging evidence now suggests that neural markers obtained from electroencephalographic (EEG) offer a valid approach for - tracking the development of cognitive functions in the infant brain. The BabyMinder provides a proof-of-concept for a novel EEG portable system combined with a sensory stimulation application to track normal and impaired neurocognitive processing in - infants. Its main purpose will be to help the diagnosis of neurodevelopmental disorders. The BabyMinder will be fully embedded in a wearable system and will feature active electrodes, which provide reliable EEG signals, yet do not require any - electrolyte gel or humidification. Although several low-cost and fully portable systems have recently been developed for adults, none of these portable systems has been adapted to infant populations. It will also consist of a functional localizer for - the automatic tracking of neurocognitive components. This functional localizer will consist of a stimulation protocol with various types of stimuli presented every few seconds, tapping specific levels of representation while the EEG device will - monitor the deployment of dedicated neurocognitive components in real-time. The whole procedure will be embedded in children-friendly animations to keep infants interested. In time, a large database of participants will be collected and combined with - state-of-the-art machine learning algorithms using a big data approach, improving the classification of normal vs. impaired neurocognitive processes. We aim to make the BabyMinder a standard tool for the diagnosis of neurodevelopmental disorders in - the future. - - 2018-12-31, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - France - - - BabyMinder - - - ERC-2017-PoC - - - 768527 - - - - - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - - - EUR 2 000 000 - - - Encapsulated eukaryotic ribosome assembly - - - EUR 2 000 000 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The production of fully functional ribosomes is vital for every cell, with failure causing human diseases called ribosomopathies. Eukaryotic ribosome assembly is catalyzed by ~200 assembly factors that guarantee efficient and - accurate production of ribosomal subunits along a temporally and spatially ordered pathway. About one third of these factors are utilized in the formation of the earliest biogenesis intermediate, termed 90S pre-ribosome or small subunit processome. - Recent insight into the 90S structure from a eukaryotic thermophile, Chaetomium thermophilum, has provided a first spatial impression on this most sophisticated process, which includes co-transcriptional RNA folding and processing, and incorporation - of ribosomal proteins. Our key discovery was that the nascent ribosomal RNA, which if linear would form a long thread, is co-transcriptionally mounted into a mold formed by a highly interconnected RNA-protein scaffold on the 90S pre-ribosome. This - finding raises a novel concept in RNA biology that nascent RNA folds and matures in a protected environment, which is reminiscent of protein folding that can also occur in folding chambers. I plan to challenge the idea that the 90S particle indeed - encapsulates the RNA transiently, in order to protect it from unproductive interactions, allowing stepwise folding and maturation in a cascade of interdependent reactions and the involvement of energy-consuming enzymes. The groundbreaking aim of this - proposal is to decipher how these processes occur in an encapsulated environment, using C. thermophilum as a model organism. This high-risk project will depend on the successful establishment of novel assays that recapitulate eukaryotic ribosome - assembly in vitro, exploiting the thermostable nature of the 90S pre-ribosome. Mechanistic insight into ribosome biogenesis will lead to a better understanding of how this multifaceted process is linked to other key cellular pathways and development - of diseases including cancer. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - Glowsome - - - ERC-2016-ADG - - - 741781 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - - - EUR 175 866 - - - Excited and exotic hadron resonances from Quantum Chromodynamics - - - EUR 175 866 - - - Ireland - - - Higher or Secondary Education Establishments - - This project will investigate the newly observed and poorly-understood `XYZ' resonances seen in the spectrum of charmonium resonances around the open-charm threshold. These states are difficult to explain in a simple quark - model and a full understanding of their nature requires lattice quantum chromodynamics to provide an ab-initio framework. One important candidate to describe some of these states is a tetraquark configuration of a bound charm quark and anti-quark - coupled non-trivially to a light quark and anti-quark. The technical expertise to perform these lattice calculations has only recently been developed and it will be tested and extended in this collaborative project by combining the expertise of the - fellow and the PI. - - - 2019-06-29, ongoing project - - - 2017-06-30 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Ireland - - - XXQCD - - - H2020-MSCA-IF-2016 - - - 749850 - - - - - UNIVERSITAT TRIER - - - EUR 171 000 - - - City Campus meets Illuminale 2016 / 2017 - - - EUR 386 750 - - - Germany - - - Higher or Secondary Education Establishments - - With the slogan “Brainwaves” the Researchers’ Night in Trier – City Campus meets Illuminale– will be showing that science is for everyone. There is a researcher in all of us. You only need a clever mind and a lot of curiosity. - Our aim is to organize a public event showing on the one hand the exciting, interesting side of science and on the other hand how science can improve the citizens' everyday life. Another main target is to enhance public recognition of researchers and - their role in society. Practical results of research will be delivered in a comprehensive and illustrative form, showing that science is all around us. To simulate everyday life situations the City Campus is grouped into seven Science Sceneries in - the heart of the City. In these Sceneries different research presentation formats will be organized, using new formats of knowledge transfer. To bring science and researchers into peoples’ everyday life, the Sceneries will take place in unusual - settings representing peoples’ normal life, e.g. the Science market place with Stage and European Corner, the Scientific Theatre and the area “Science goes to school”. The City Campus program includes hands on experiments and demonstrations, shows, - contests, quizzes, exhibitions and much more. A significant number of researchers will participate in public events to interact face-to-face with the public. The visitors – mobilized through an extensive awareness campaign – will be given the chance - to touch, feel and smell science. To increase the attractiveness the effective event Illuminale will be integrated in the European Researchers’ Night. Artistic illuminations of buildings and places will be combined with interesting spotlights on - several areas of research. These spotlights are a metaphor for science and knowledge. Partners are the Trier University of Applied Sciences, the ttm trier Tourismus & Marketing GmbH and the Municipality of Trier. - - 2017-11-30, closed project | - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.5."> - - - MSCA-NIGHT-2016 - European Researchers' Night - - - CSA - Coordination and support action - - - Germany - - - Brainwaves - - - H2020-MSCA-NIGHT-2016 - - - 722955 - - - - - KARLSRUHER INSTITUT FUER TECHNOLOGIE - KARLSRUHER INSTITUT FUER TECHNOLOGIE - - - EUR 2 499 981 - - - Multidimensional CRISPR/Cas mediated engineering of plant breeding - - - EUR 2 499 981,27 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The implementation of CRISPR/Cas technology has already revolutionised biology and biotechnology. However, for plant breeding its full potential has hardly been applied. The gene pool of a plant species carries a tremendous - amount of information regarding how to survive best under various biotic and abiotic stresses. Although countless wild varieties of crops have been safeguarded in gene banks worldwide, much of their genetic information cannot be used in agriculture. - Often, adverse and/or favourite traits are linked due to the fact that respective genes are located within close proximity, on the same chromosome. Breeding aims not only to break linkages between such traits but also to tightly fix favourable - linkages. In cereals, half of the genome cannot be accessed by classical breeding. The aim of this proposal is to develop techniques based on CRISPR/Cas technology, to engineer plant breeding on the molecular level. With the use of the Cas9 nuclease - of S. pyogenes and multiple sgRNAs, it became possible to induce several genomic changes at the same time. The aim of this proposal is to perform genome engineering on a multidimensional level by not only inducing multiple DNA lesions (single and - double stranded breaks) but also by applying different Cas9 orthologues to simultaneously target DNA recombination factors directly to the sites of action, or indirectly by influencing their expression. Thus, site-specific initiation of recombination - should be coupled with pathway choice, resulting in novel approaches for breaking or fixing linkages. Techniques for genome restructuring, like inversions and translocations, should be established as well as efficient induction of somatic and meiotic - crossovers. Therefore, the basis should be laid for combining the best available traits of a species, resulting in transgene free crop plants for a sustainable agriculture. Furthermore, the Cas9-controlled transfer of chromosomal segments between - species will also be addressed. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - CRISBREED - - - ERC-2016-ADG - - - 741306 - - - - - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - - - EUR 2 351 550 - - - Designing Conjugated Polymers for Photocatalysis and Ion Transport - - - EUR 2 351 550 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Solar energy conversion will play an essential role in the future supply of clean energy. Secure access to energy sources will require energy conversion technologies that are low impact, distributed and accessible both - technically and financially. Molecular electronic materials embody these possibilities, offering facile synthesis, low energy production and the versatility to allow performance to be maximized for specific applications. Moreover, they bring - appealing similarities with nature’s intrinsically low impact energy conversion materials. Whilst molecular semiconductors have been studied in detail for solar-to-electric energy conversion they have seldom been studied for solar-to-chemical - conversion or for charge storage. However, they bring exciting potential advantages in terms of their light harvesting properties, the range of microstructures possible and the ability to tune their electrical properties. Polymer materials applied to - solar chemical generation could open up an innovative route to artificial fuels, with the option to control light harvesting and charge separation through structural control. Polymer materials applied to mixed (electronic / ionic) conduction provide - a route to lower cost electrochemical storage, as well as to biocompatible devices and sensors. Stimulated by recent experimental breakthroughs in the application of polymers as photocatalysts and ion transport media I will exploit my expertise in - multi-scale modelling and functional characterization of molecular electronic materials and devices to develop a design framework for energy conversion and storage in conjugated polymer materials. This proposal aims to disentangle the parameters that - govern the performance of conjugated polymer based photocatalysts and ion transport media to discover the underlying functional mechanisms. The tools generated will serve to enable the design and development of high performance materials for energy - conversion devices. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - CAPaCITy - - - ERC-2016-ADG - - - 742708 - - - - - FORSCHUNGSINSTITUT FUR MOLEKULARE PATHOLOGIE GESELLSCHAFT MBH - FORSCHUNGSINSTITUT FUR MOLEKULARE PATHOLOGIE GESELLSCHAFT MBH - - - EUR 2 500 000 - - - Transcriptional control of plasma cell development and function - - - EUR 2 500 000 - - - Austria - Austria - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Antibody-secreting cells consisting of short-lived proliferating plasmablasts and long-lived quiescent plasma cells are essential for the acute response to infection and long-term protection of the host against pathogens. Only - a few regulators (Blimp1, IRF4, XBP1, Aiolos, Ikaros and E-proteins) have been implicated in the transcriptional control of antibody-secreting cells, and their target genes, with the exception of Blimp1 and E-proteins, are still unknown. This - proposal aims to systematically identify key players in the development and function of antibody-secreting cells by using the CRISPR/Cas9 and Cre/loxP methods. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Austria - - - PlasmaCellControl - - - ERC-2016-ADG - - - 740349 - - - - - UNIVERSITAET KLAGENFURT - UNIVERSITAET KLAGENFURT - HUMBOLDT-UNIVERSITAET ZU BERLIN - - - EUR 2 483 686 - - - Understanding the Role of Material Stock Patterns for the Transformation to a Sustainable Society - - - EUR 2 483 686,06 - - - Austria - Austria - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Sustainability transformations imply fundamental changes in the societal use of biophysical resources. Current socioeconomic metabolism research traces flows of energy, materials or substances to capture resource use: input of - raw materials or energy, their fate in production and consumption, and the discharge of wastes and emissions. This approach has yielded important insights into eco-efficiency and long-term drivers of resource use. But due to its focus on flows, - socio-metabolic research has not yet incorporated material stocks or their services, thereby not fully realizing its analytic potential. MAT_STOCKS addresses this gap by developing a consistent typology, indicators and databases of material stocks - and their services, building upon economy-wide material flow analysis. It will create a comprehensive, global, national-level, validated material stocks and services database as well as maps of material stocks from remote-sensing data. This will - allow analyzing the stock/flow/service nexus and underpin highly innovative indicators of eco-efficiency overcoming limitations of current approaches which mainly relate resource use or emissions to population and GDP. New insights on - stock/flow/service relations, the relevance of spatial patterns and options for decoupling will be used to create a dynamic model to assess option spaces for transformations towards sustainable metabolism. MAT_STOCKS will identify barriers and - leverage points for future sustainability transformations and the SDGs, and elucidate their socio-ecological and political implications. Our preliminary analyses suggest that unravelling the stock/flow/service nexus provides a crucial missing link in - socio-metabolic research because it explains why, how and where patterns of material and energy use change or remain locked-in. Thereby, important analytical insights will be introduced into the largely normative and local discourses on the - transformation towards a sustainable society. - - 2023-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Austria - - - MAT_STOCKS - - - ERC-2016-ADG - - - 741950 - - - - - UNIVERSITY OF LEEDS - UNIVERSITY OF LEEDS - - - EUR 2 271 830 - - - Intelligent corrosion management underpinned by advanced engineering science - - - EUR 2 271 830 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Our planet’s population will continue to grow rapidly; between 2010 and 2025 the population will grow by 1.1bn. Urbanisation and growth of the consumer class in developing countries will lead to unprecedented demands on - energy. There is arguably no bigger challenge to society than ensuring the security of affordable and environmentally-sustainable energy. - - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - INTELLICORR - - - ERC-2016-ADG - - - 742930 - - - - - UNIVERSITAET BERN - UNIVERSITAET BERN - - - EUR 1 493 736 - - - Neuronal circuits for emotions in the ventral CA1 hippocampus - - - EUR 1 493 736 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - A fundamental objective in modern neurosciences is to understand the neural mechanisms of learning and memory in both healthy and pathological conditions. The hippocampus is a high-order cortical brain region important for - emotions and cognition. The ventral subdivision of the hippocampus (anterior hippocampus in primates) is mostly involved in anxiety and contextual fear conditioning behaviours. - - - 2021-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Switzerland - - - ventralHippocampus - - - ERC-2016-STG - - - 716761 - - - - - UNIVERSITAET LEIPZIG - UNIVERSITAET LEIPZIG - - - EUR 2 379 250 - - - What Holds Cancer Cells Back? - - - EUR 2 379 250 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Since decades the bulk of cancer research focusses on the genetic and molecular level. To complement this knowledge, I will focus on the collective behaviour of cancer cells in cell clusters and in the extracellular matrix (ECM). - - 2022-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - HoldCancerBack - - - ERC-2016-ADG - - - 741350 - - - - - FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION - FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION - - - EUR 2 358 625 - - - Cyclical and Linear Timing Modes in Development - - - EUR 2 358 625 - - - Switzerland - Switzerland - - - Research Organisations - Research Organisations - - Organismal development requires proper timing of events such as cell fate choices, but the mechanisms that control temporal patterning remain poorly understood. In particular, we know little of the cyclical timers, or - ‘clocks’, that control recurring events such as vertebrate segmentation or nematode molting. Furthermore, it is unknown how cyclical timers are coordinated with the global, or linear, timing of development, e.g. to ensure an appropriate number of - cyclical repeats. We propose to elucidate the components, wiring, and properties of a prototypic developmental clock by studying developmental timing in the roundworm C. elegans. We build on our recent discovery that nearly 20% of the worm’s - transcriptome oscillates during larval development – an apparent manifestation of a clock that times the various recurring events that encompass each larval stage. Our aims are i) to identify components of this clock using genetic screens, ii) to - gain insight into the system’s architecture and properties by employing specific perturbations such as food deprivation, and iii) to understand the coupling of this cyclic clock to the linear heterochronic timer through genetic manipulations. To - achieve our ambitious goals, we will develop tools for mRNA sequencing of individual worms and for their developmental tracking and microchamber-based imaging. These important advances will increase temporal resolution, enhance signal-to-noise ratio, - and achieve live tracking of oscillations in vivo. Our combination of genetic, genomic, imaging, and computational approaches will provide a detailed understanding of this clock, and biological timing mechanisms in general. As heterochronic genes and - rhythmic gene expression are also important for controlling stem cell fates, we foresee that the results gained will additionally reveal regulatory mechanisms of stem cells, thus advancing our fundamental understanding of animal development and - future applications in regenerative medicine. - - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Switzerland - - - CYCLODE - - - ERC-2016-ADG - - - 741269 - - - - - UNIVERSITAET SIEGEN - UNIVERSITAT TRIER - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - SWANSEA UNIVERSITY - THE UNIVERSITY OF BIRMINGHAM - INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE - UNIVERZA V LJUBLJANI - UNIVERSITEIT MAASTRICHT - STOCKHOLMS UNIVERSITET - UNIVERSITA DEGLI STUDI DI PADOVA - UNIVERSIDADE DO ALGARVE - ASTON UNIVERSITY - Fachhochschule Dortmund - - - EUR 958 500 - - - Computing with Infinite Data - - - EUR 1 462 500 - - - Germany - Germany - Germany - United Kingdom - United Kingdom - France - Slovenia - Netherlands - Sweden - Italy - Portugal - United Kingdom - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The joint research in this programme will study important aspects—both theoretical as well as applied—of computing with infinite objects. A central aim is laying the grounds for the generation of efficient and verified - software in engineering applications. - - - 2021-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Germany - - - CID - - - H2020-MSCA-RISE-2016 - - - 731143 - - - - - UNIVERSITAET BERN - - - EUR 187 419,60 - - - DNA repair mechanisms and therapy resistance of BRCA2-deficient cancers - - - EUR 187 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - Despite the existence of various novel anti-cancer treatments, drug resistance remains a major cause of death in patients with disseminated cancer. To increase specificity and efficacy, modern treatment strategies in molecular - oncology employ the “synthetic lethality” concept. An example are BRCA1/2-deficient breast and ovarian cancers that lack DNA repair by homologous recombination (HR). Due to this defect, tumor cells rely more on other DNA repair pathways. When such - alternative pathways are jammed, e.g. by poly(ADP-ribose) polymerase inhibitors (PARPi), normal cells with intact HR can survive, whereas cancer cells die. However, even with this sophisticated treatment strategy, resistance to PARPi still occurs and - greatly reduces patient survival. The mechanisms driving this resistance are still largely unknown. The main goal of this project is to advance the knowledge on therapy resistance by using a genetically engineered mouse model of BRCA2-deficient - breast cancer, which closely mimics the human disease. Like in patients, cancer cells in these animals eventually escape from therapy. I will start by synergizing the next generation sequencing analysis of spontaneous resistant mouse tumors with - functional genetic screens using the CRISPR/Cas9 technology. This combination has yielded interesting candidate genes whose loss of function may cause resistance. Two promising candidates, MDC1 and Claspin, will be further investigated using - innovative and physiologically relevant 3D tumor organoid cultures. Moreover, I will apply my expertise in modern imaging technology to develop novel approaches to visualize DNA repair dynamics in resistant tumors in vitro and in vivo. I am convinced - that by understanding basic resistance mechanisms, smart biosensors can be built to image the DNA damage response and eventually improve clinical decision making. I believe this project will have an impact on the design of strategies to overcome - therapy escape in human cancer patients. - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - DREMATURE - - - H2020-MSCA-IF-2016 - - - 743290 - - - - - FUNDACION CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III - ACQUIFER AG - Leica Microsystems CMS GmbH - CENTRE EUROPEEN DE RECHERCHE EN BIOLOGIE ET MEDECINE - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSITAET BERN - PHILIPS IBERICA SA - - - EUR 1 529 110,80 - - - 4D analysis of heart development and regeneration using advanced light microscopy - - - EUR 1 529 110,80 - - - Spain - Germany - Germany - France - France - Switzerland - Spain - - - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Cardiovascular (CV) disease is a main cause of death worldwide. During adulthood, ischemic heart disease leads to heart failure and perinatally, congenital heart defects are found in over 20% of deaths. Moreover, genetic or - epigenetic factors altering development can have an impact much later in life. These facts underscore the need of a better understanding of the genetic and environmental factors that influence CV development. An important way to increase our - knowledge is by visualizing cardiac development in vivo. Recent advance in microscopy allows monitoring CV development at a cellular level in organisms such as the zebrafish model. Particularly revolutionary has been the development of light sheet - microscopy (LSM). We want to further exploit LSM for in vivo manipulation of cells in the embryonic zebrafish heart and measure with high precision biophysical parameters, by introducing novel features to LSM such as optical tweezers. High throughput - cardiac imaging protocols for zebrafish larvae suitable for screenings will be set up. We will develop softwares to enhance resolution of acquisition, large dataset handling and image-processing. The aim is to generate a toolbox to be implemented - into existing software packages allowing a complete modeling of zebrafish cardiac morphogenesis. We will adapt LSM for adult zebrafish hearts to study cardiac regeneration and mouse heart development at cellular resolution. Each Early Stage - Researchers (ESRs) will develop their own technology to solve a biological problem at the frontier of knowledge. ESRs will receive multidisciplinary (CV development, physics, biocomputing, bioimaging) as well as intersectorial (academic research, - SMEs, large companies) training and will achieve unique skills on microscopy, in-vivo imaging and image analysis allowing them to interrogate questions on cardiac development and regeneration. Their profile will be at the interface of a bioengineer - and a life science researcher filling a currently existing gap on the market. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-EID - European Industrial Doctorates - - - Spain - - - 4DHeart - - - H2020-MSCA-ITN-2016 - - - 722427 - - - - - TECHNISCHE UNIVERSITEIT EINDHOVEN - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - FRIEDRICH-SCHILLER-UNIVERSITAT JENA - UNIVERSITAT LINZ - IBM RESEARCH GMBH - TECHNISCHE UNIVERSITAET MUENCHEN - - - EUR 3 985 417,50 - - - SiliconLaser - - - EUR 3 985 418,75 - - - Netherlands - United Kingdom - Germany - Austria - Switzerland - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - Our research aims to revolutionize the electronics industry by adding intra-chip and chip-to-chip communication at the speed of light, offering a significantly reduced energy consumption. Cubic crystal phase SiGe is known to - be great for electronics. We propose to develop hexagonal crystal phase SiGe (Hex-SiGe) which features a direct bandgap and will add photonic capabilities to electronics. Direct bandgap silicon has been the holy grail of the semiconductor industry - for many years, since it would allow integrating both electronic and optical functionalities on a silicon platform. Recent theoretical calculations predict that hexagonal crystal phase SixGe1-x features a tunable direct bandgap from 1380-1800 nm, - exactly coinciding with the low loss window for optical fibre communications. We have recently developed a generic approach to grow defect-free hexagonal SixGe1-x with tunable composition. We propose to demonstrate efficient light emission from - direct bandgap SiGe, followed by the development of a SiGe nanolaser. Work towards CMOS integration is included. The demonstration of a Hex-SiGe nanolaser will serve as a game-changer for transforming the electronics industry. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-01-2016-2017 - FET-Open research and innovation actions - - - RIA - Research and Innovation action - - - Netherlands - - - SiLAS - - - H2020-FETOPEN-1-2016-2017 - - - 735008 - - - - - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - KOBENHAVNS UNIVERSITET - FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG - AALTO-KORKEAKOULUSAATIO - UNIVERSITA DEGLI STUDI DI CAMERINO - UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6 - UNIVERSITAT WIEN - UNIVERSITAET HAMBURG - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSITAT KONSTANZ - UNIVERSITEIT GENT - TECHNISCHE UNIVERSITEIT DELFT - IBM RESEARCH GMBH - ROBERT BOSCH GMBH - - - EUR 3 897 454,32 - - - OMT - Optomechanical Technologies - - - EUR 3 897 454,32 - - - Switzerland - Denmark - Germany - Finland - Italy - France - Austria - Germany - France - Germany - Belgium - Netherlands - Switzerland - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The proposed project is built on the successful training and research experience of the leading European research groups working in the field of cavity optomechanics. Our ENT unites a total of 14 leading groups in the field, - of which two are major industrial players that utilize MEMS and NEMS - Bosch and IBM. The main goal of the project is to exploit optomechanical interactions in views of novel functionality and possible applications of cavity optomechanical systems - that were envisioned by consortium partners during their previous research activities. - - - 2020-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Switzerland - - - OMT - - - H2020-MSCA-ITN-2016 - - - 722923 - - - - - UPPSALA UNIVERSITET - UPPSALA UNIVERSITET - - - EUR 1 494 880 - - - Chemistry and Biology in Synergy - Studies of hydrogenases using a combination of synthetic chemistry and biological tools - - - EUR 1 494 880 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - My proposal aims to take advantage of my ground-breaking finding that it is possible to mature, or activate, the [FeFe] hydrogenase enzyme (HydA) using synthetic mimics of its catalytic [2Fe] cofactor. (Berggren et al, Nature, - 2013) We will now explore the chemistry and (bio-)technological potential of the enzyme using an interdisciplinary approach ranging from in vivo biochemical studies all the way to synthetic model chemistry. Hydrogenases catalyse the interconversion - between protons and H2 with remarkable efficiency. Consequently, they are intensively studied as alternatives to Pt-catalysts for these reactions, and are arguably of high (bio-) technological importance in the light of a future “hydrogen society”. - - 2022-01-31, ongoing project - - - 2017-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Sweden - - - CaBiS - - - ERC-2016-STG - - - 714102 - - - - - GOETEBORGS UNIVERSITET - UPPSALA UNIVERSITET - Asociacion - Centro de Investigacion Cooperativa en Nanociencias - CIC NANOGUNE - UNIVERSITA DEGLI STUDI DI FIRENZE - UNIVERSITY OF YORK - STICHTING KATHOLIEKE UNIVERSITEIT - PAUL SCHERRER INSTITUT - NANOSC AB - UNIVERSITA DI PISA - THALES SA - - - EUR 3 712 832,50 - - - Spinoptical nanoantenna-assisted magnetic storage at few nanometers on femtosecond timescale - - - EUR 3 712 832,50 - - - Sweden - Sweden - Spain - Italy - United Kingdom - Netherlands - Switzerland - Sweden - Italy - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - We will develop the conceptually new paradigm for ultra-dense and ultrafast magnetic storage that will exceed the current technology by two orders of magnitude in storage density (going from terabit/inch2 to tens of - terabytes/inch2) and by about four orders of magnitude in operation speed (going from low GHz to THz for read/write). This will be achieved in an all-optical platform that allows deterministic, non-thermal, low-energy, ultrafast magnetization - switching at few nanometers and potentially down to a molecular length-scale. The main building block of the envisioned memory unit in this new paradigm is the spinoptical nanoplasmonic antenna that concentrates pulsed polarized light at the - nanometer length-scale and enables non-thermal spin-orbit mediated transfer of the light’s angular momentum (orbital and/or spin) to the nanoscale magnetic architectures. In this way fs-pulsed light, assisted by the plasmonic optical spin-selective - antenna and the local electromagnetic field enhancement, allows for the precise control of the magnetic state of nanometer sized / molecular magnetic structures. The project aims to elucidate the fundamentals of the emergence and manipulation of - light’s orbital and spin angular momenta to achieve non-thermal momentum-transfer-driven ultrafast switching process, to demonstrate its practical realization, and will map its suitability for future upscaling towards industrial implementation in - devices. - - 2020-02-29, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-01-2016-2017 - FET-Open research and innovation actions - - - RIA - Research and Innovation action - - - Sweden - - - FEMTOTERABYTE - - - H2020-FETOPEN-1-2016-2017 - - - 737093 - - - - - UNIVERSITAET BERN - UNIVERSITAET BERN - - - EUR 2 000 000 - - - Connectivity Correlate of Molecular Pathology in Neurodegeneration - - - EUR 2 000 000 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Neurodegenerative diseases (NDs) are incurable, debilitating conditions, arise mid-late in life, represent an enormous health and socioeconomic burden and no therapies exist. An enigmatic finding in NDs is the early and - selective alteration in intrinsic excitability of vulnerable neurons paralleling changes in its circuitry. However, a gap in understanding exists in ND field about the cause of these alterations and whether these modifications regulate degenerative - pathomechanisms. Our recent study, examining mechanisms of Purkinje cell (PC) degeneration in Spinocerebellar ataxia type 1 (SCA1) revealed that the earliest cerebellar alterations occur in the major excitatory inputs onto PCs, the climbing fibers - (CFs). Based on this, we propose a novel three-step model of neurodegeneration: First, suboptimal functioning of the presynaptic inputs initiates signaling deficits in target PCs. Second, those alterations trigger maladaptive responses such as - altered intrinsic PC excitability, thus amplifying pathogenic cascades. Third, at network level progressive dysfunction triggers compensatory synaptic modifications within the cerebellar circuitry. In this proposal, we will test our new hypothesis - for NDs on SCA1 and this will be the first study to test circuit-dependency in NDs by selectively silencing presynaptic inputs and examining molecular responses in the postsynaptic neuron. Specifically, we will 1) Identify the dysfunctional CF - associated molecular signature in PCs. 2) Elucidate mechanisms involved in altering intrinsic PC excitability. 3) Map the connectome for a structural correlate of the pathology. Using conditional mouse models, pharmacogenetics, transcriptomics, - proteomics and connectomics, we will delineate molecular alterations that govern disease from compensatory alterations. Our systematic approach will not only impact SCA related therapies but the entire spectrum of NDs and has the potential to change - the conceptual approach of future studies on NDs. - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Switzerland - - - ConCorND - - - ERC-2016-COG - - - 725825 - - - - - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH - STIFTUNG DEUTSCHES ELEKTRONEN-SYNCHROTRON DESY - ISTITUTO NAZIONALE DI FISICA NUCLEARE - THE HENRYK NIEWODNICZANSKI INSTITUTE OF NUCLEAR PHYSICS, POLISH ACADEMY OF SCIENCES - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - SCIENCE AND TECHNOLOGY FACILITIES COUNCIL - UPPSALA UNIVERSITET - PAUL SCHERRER INSTITUT - KARLSRUHER INSTITUT FUER TECHNOLOGIE - - - EUR 2 279 750 - - - Accelerator and Magnet Infrastructure for Cooperation and Innovation - - - EUR 2 279 750 - - - France - Switzerland - Germany - Italy - Poland - France - United Kingdom - Sweden - Switzerland - Germany - - - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - - Development and construction of accelerator based scientific Research Infrastructures are going through a deep paradigm change because of the need for large scale Technological Infrastructures at the forefront of technology to - master the key accelerator and magnet science and technology needed for several fields. Indeed, because of the high technological level and of the increased size and time scale of projects, development and construction require more and more - sophisticated R&D platforms on key accelerator and magnet technologies, large-scale facilities for their assembly, integration and verification, large concentrations of dedicated skilled personnel and long term relationships between laboratories - and industry. In response to those challenges, a few large platforms specialized in interdisciplinary technologies and for applications of direct benefit to society are emerging. The emerging Technological Infrastructure is aiming at creating an - efficient integrated ecosystem among laboratories focussed on R&D, with a long term vision for the technological needs of future RIs and industry, including SME, motivated by the innovative environment and the market created by the realisation of - the technological needs of several RIs. With a timeline of 30 months, involving 10 Consortium partners, the AMICI proposal will ensure that A) a stronger and optimised integration model between the large existing technological infrastructures is - developed and agreed upon, B) that this integrated ecosystem is attracting industries and fostering innovation based on accelerator and SC magnets cutting-edge developments, C) that strategy and roadmaps are clearly defined and understood to strongly - position European industries and SMEs on the market of the construction of new Research Infrastructures worldwide, and D) that potential societal applications are identified and disseminated to the relevant partners of this ecosystem. - - 2019-06-30, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.2.1."> - - - INFRAINNOV-02-2016 - Support to Technological Infrastructures - - - CSA - Coordination and support action - - - France - - - AMICI - - - H2020-INFRAINNOV-2016-1 - - - 731086 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - UPPSALA UNIVERSITET - CENTRO DE NEUROCIENCIAS E BIOLOGIACELULAR ASSOCIACAO - THE HEBREW UNIVERSITY OF JERUSALEM - UNIVERZA V LJUBLJANI - NIMGENETICS, GENOMICA Y MEDICINA S.L. - BNML BEHAVIORAL & MOLECULAR LAB - FUNDACION PARA LA INVESTIGACION BIOMEDICA DEL HOSPITAL UNIVERSITARIO LA PRINCESA - CELL STRESS DISCOVERIES LIMITED - - - EUR 3 750 898,68 - - - Training European Network: Metabolic Dysfunctions associated with Pharmacological Treatment of Schizophrenia - - - EUR 3 750 898,68 - - - Spain - Sweden - Portugal - Israel - Slovenia - Spain - Portugal - Spain - Ireland - - - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - TREATMENT is a Marie Sklodowska Curie Innovative Training Network proposal directly addressing the need for high-level training and career paths in risk evaluation of drug induced metabolic dysfunctions, a relevant aspect, so - far unexplored by traditional toxicology studies, but urgently needed to challenge current severe limitations of health care interventions in mental disorders. These patients require life-long medications that subsequently trigger metabolic diseases - with a strong negative impact on their health and well-being. To achieve this, and improve adherence to treatments, we will evaluate how short-term antipsychotic drug responses impact long-term metabolic control to identify and validate biomarkers - with clinically predictive value for targeting drug induced metabolic dysfunctions. This effort will have added commercial value by enabling the design of predictive marker kits for testing adverse secondary metabolic effects of drugs to be used in - pharmacological and medical practice. TREATMENT will provide multidisciplinary knowledge, capabilities and tools to implement this ambitious strategy by the training of young scientists in a program that combines pharmacology, metabolism and mental - health research with strategies for product and tool design and validation. Our ultimate goal is to empower the intersectorial and trans-national employability of young scientists across academic, public and private sectors to foster the development - and implementation of personalized medicine tools that will provide effective treatment regimens for life long health-care interventions and decrease the risk for development of chronic metabolic diseases. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Spain - - - TREATMENT - - - H2020-MSCA-ITN-2016 - - - 721236 - - - - - UPPSALA UNIVERSITET - UPPSALA UNIVERSITET - - - EUR 1 498 954 - - - Single-Molecule And Structural Studies Of ATP-Dependent Chromatin Remodelling - - - EUR 1 498 954 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The packaging of genetic information into chromatin regulates a wide range of vital processes that depend on direct access to the DNA template. Many chromatin-interacting complexes impact chromatin structure and their aberrant - regulation or dysfunction has been implicated in various cancers and severe developmental disorders. A better understanding of the roles of chromatin-interacting complexes in such disease states requires a detailed mechanistic study. Many - chromatin-interacting complexes modify chromatin structure, yet understanding the underlying mechanisms remains a major challenge in the field. Furthermore, how chromatin-interacting complexes are regulated to enable their various functions is - incompletely understood. We will address these longstanding questions in two specific aims. Aim I: Building on our expertise in single-molecule biology, we will develop powerful single-molecule imaging approaches to monitor the action of - chromatin-interacting complexes in real time. We will further probe how the diverse activities of the chromatin-associated complexes are coordinated and coupled to conformational transitions. Aim II: Drawing on our expertise in structural biology, we - will use a range of structural techniques in combination with biochemical approaches to study the vital regulation of chromatin-interacting complexes by their regulatory subunits as well as by chromatin features. We expect to obtain ground-breaking - insights into the mechanisms and regulation of disease-related chromatin-associated complexes, which may open up new horizons for developing therapeutic intervention strategies. Furthermore, the approaches developed here will enable the investigation - of a large number of chromatin-related processes. - - 2022-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Sweden - - - ChromatinRemodelling - - - ERC-2016-STG - - - 714068 - - - - - UPPSALA UNIVERSITET - UPPSALA UNIVERSITET - - - EUR 1 610 000 - - - Coordination and Composability: The Keys to Efficient Memory System Design - - - EUR 1 610 000 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Computer systems today are power limited. As a result, efficiency gains can be translated into performance. Over the past decade we have been so effective at making computation more efficient that we are now at the point where - we spend as much energy moving data (from memory to cache to processor) as we do computing the results. And this trend is only becoming worse as we demand more bandwidth for more powerful processors. To improve performance we need to revisit the way - we design memory systems from an energy-first perspective, both at the hardware level and by coordinating data movement between hardware and software. - - 2022-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Sweden - - - CC-MEM - - - ERC-2016-STG - - - 715283 - - - - - UNIVERSITAET BERN - UNIVERSITAET BERN - - - EUR 1 404 062 - - - Unique Method for a Neutron Electric Dipole Moment Search using a Pulsed Beam - - - EUR 1 404 062 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - My research encompasses the application of novel methods and strategies in the field of low energy particle physics. The goal of the presented program is to lead an independent and highly competitive experiment to search for a - CP violating neutron electric dipole moment (nEDM), as well as for new exotic interactions using highly sensitive neutron and proton spin resonance techniques. - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Switzerland - - - BEAM-EDM - - - ERC-2016-STG - - - 715031 - - - - - UNIVERSITAT ZURICH - - - EUR 187 419,60 - - - “FINancial and REAL Sector NETworks in Europe” - - - EUR 187 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - Banks’ exposures to similar asset groups could become an important source of contagion when combined with interbank network spillovers. The FINREALNET project aims at elaborating a common portfolio network-based stress-test - framework that could find application in regular stress-testing exercises carried out by the regulator. Using an innovative DebtRank-based model FINREALNET suggests identifying Systemically Important Real Sectors (SIRS) at the euro area and test - stabilizing effects of sector targeting macro-prudential tools. The Project will comparatively assess the resilience of European Banks to losses on common exposures pre- and post- QE, as the structure of overlapping networks is expected to change - after the QE. The FINREALNET project is a perfect springboard for the Principal Investigator (PI) through the possibility to build durable research network, and acquire new skills which are complementary to her current expertise. Those new skills - include research skills (theory and methodology), operational skills (algorithm writing), project management skills, language skills (German) and new data treatment skills (during the Secondment at the ECB). Moreover, working papers, presentations - and recommendations for the regulator will improve the PI’s visibility as a young researcher and contribute to her research career. FINREALNET also builds a solid foundation for future collaborations. Finally, FINREALNET by its training and research - program aims at promoting women’s integration in the domain of Economic research where a traditional gender gap persists. - - 2018-05-31, Grant Agreement terminated - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - FINREALNETS - - - H2020-MSCA-IF-2015 - - - 704936 - - - - - UPPSALA UNIVERSITET - - - EUR 185 857,20 - - - Towards an Inclusive Common European Framework for Assisted Reproductive Technologies (ART): Queer Transgender Reproduction in the Age of ART. - - - EUR 185 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - The use and regulation of Assisted Reproductive Technologies (ARTs) has undergone repeated significant changes since the 1980s, partly to accommodate biotechnological developments, partly to recognize shifts in socio-cultural - practices of kinship and family. These changes have generally been towards greater inclusivity but have been variedly legislated and implemented in the diverse European countries, leading to ‘reproductive migration’. As the numbers of ART users and - clinics rise, there is a clear need to provide a common European framework for ART: this is the purpose of this project. - - 2019-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - QTReproART - - - H2020-MSCA-IF-2016 - - - 749218 - - - - - UNIVERSITAET BERN - UNIVERSITAET BERN - UNIVERSITE DE FRIBOURG - - - EUR 1 498 275 - - - Organic Semiconductors Interfaced with Biological Environments - - - EUR 1 498 275 - - - Switzerland - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Transducing information to and from biological environments is essential for bioresearch, neuroscience and healthcare. There has been recent focus on using organic semiconductors to interface the living world, since their - structural similarity to bio-macromolecules strongly favours their biological integration. Either water-soluble conjugated polyelectrolytes are dissolved in the biological medium, or solid-state organic thin films are incorporated into bioelectronic - devices. Proof-of-concept of versatile applications has been demonstrated – sensing, neural stimulation, transduction of brain activity, and photo-stimulation of cells. However, progress in the organic biosensing and bioelectronics field is limited - by poor understanding of the underlying fundamental working principles. Given the complexity of the disordered, hybrid solid-liquid systems of interest, gaining mechanistic knowledge presents a considerable scientific challenge. The objective of - OSIRIS is to overcome this challenge with a high-end spectroscopic approach, at present essentially missing from the field. We will address: 1) The nature of the interface at molecular and macroscopic level (assembly of polyelectrolytes with - bio-molecules, interfacial properties of immersed organic thin films). 2) How the optoelectronics of organic semiconductors are affected upon exposure to aqueous environments containing electrolytes, biomolecules and cells. 3) How information is - transduced across the interface (optical signals, thermal effects, charge transfer, electric fields, interplay of electronic/ionic transport). Via spectroscopy, we will target relevant optoelectronic processes with ultrafast time-resolution, - structurally characterize the solid-liquid interface using non-linear sum-frequency generation, exploit Stark shifts related to interfacial fields, determine nanoscale charge mobility using terahertz spectroscopy in attenuated total reflection - geometry, and simultaneously measure ionic transport. - - 2022-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Switzerland - - - OSIRIS - - - ERC-2016-STG - - - 714586 - - - - - KATHOLIEKE UNIVERSITEIT LEUVEN - KATHOLIEKE UNIVERSITEIT LEUVEN - - - EUR 149 875 - - - Super-resolution genomic mapping for the microbiome - - - EUR 149 875 - - - Belgium - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Animals and bacteria have been working together for about as long as they have co-existed, long before the advent of mankind. The bodies of our ancient ancestors offered protected, nutrient-rich habitats for bacteria. In - return, animals could take an evolutionary short-cut to developing new capabilities by ‘borrowing’ bacterial genes. Indeed, when gut bacteria assist with the digestion of e.g. dietary fiber, the resulting metabolites will subsequently exert an - influence on an intricate network of host molecular pathways. Gut microbiota, in addition to host genetics, can therefore constitute a major factor in the etiology of complex disorders, ranging from obesity, cardiovascular disease, autoimmune disease - (multiple sclerosis, rheumatoid arthrosis), inflammation (inflammatory bowel disease, Crohn’s) to neurological conditions. - - 2019-05-31, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Belgium - - - METAMAPPER - - - ERC-2017-PoC - - - 768826 - - - - - FREIE UNIVERSITAET BERLIN - - - EUR 171 460,80 - - - Nanoscale Effects within Biological Membranes caused by Radiation - - - EUR 171 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - The NanoMembR project will elucidate key elements of membrane stability under the influence of UV radiation. The stability of biological membranes is of great importance for the structure, homeostasis and functioning of all - living systems. Membrane molecules have also attracted, due to their robustness and longevity, strong interest from planetary and space scientists as potential biomarkers for life detection missions to other planets. Membrane damage, perturbation, - instability and fragmentation upon UV exposure will be investigated on the nanoscale using cutting-edge infrared nanoscopy. Scattering-type scanning near-field microscopy (s-SNOM) combined with Fourier transform infrared (FTIR) spectroscopy allows to - combine spatial information of nanometre resolution with chemical mapping. This novel technique will enable us to study subtle changes in the structural integrity of model membranes and monitor changes in the micro- and nano-domains. In addition, we - will be able to correlate membrane stability and membrane composition by intercalating structural and functional modifiers such as sterols, hopanoids and pigments. Upon radiation in oxic environments, the lipid structure of a membrane is known to be - altered by peroxidation chain reactions. Under anoxic conditions radiation induced changes in lipid alteration could vary significantly, with intriguing implications for the stability of membrane molecules under different environmental conditions - than found on Earth. Understanding fragmentation patterns of membranes and identifying final break-down products will provide scientific support and a database for key biomarkers detectable in remote environments. Results from this work will feed - directly into planned experiments on the International Space Station (ISS), which are scheduled on new nanosatellite-technology-based exposure platforms with in-situ infrared spectroscopic capabilities, monitoring membrane stability under the - influence of solar and cosmic radiation. - - 2019-05-15, ongoing project - - - 2017-05-16 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - NanoMembR - - - H2020-MSCA-IF-2015 - - - 706072 - - - - - COLLEGE DE FRANCE - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 185 076 - - - Spinor Bose Gases in 1D: Equilibrium properties, Dynamics, and Spin-orbit coupling - - - EUR 185 076 - - - France - France - - - Higher or Secondary Education Establishments - Research Organisations - - The properties of materials are determined by the order in their most fundamental constituents, generally appearing at sufficiently low temperatures after a phase transition. This generic picture encompasses phenomena as - diverse as: the ordering of atoms into perfectly periodic crystals, into superfluid phases for liquid Helium or dilute atomic gases, or even cosmological phenomena. In the case of magnetic materials, usually described in terms of localized spins on - lattice, ordering refers to the spatial organization of spins. Examples of such organization are the ferromagnetic and anti-ferromagnetic phases in electronic (spin-1/2) systems: the former is characterized by the parallel alignment of adjacent - electron spins in a lattice, while the latter exhibits an antiparallel arrangement of the spins. Spin-exchange interactions are responsible for the emergence of such magnetic quantum phases. Magnetic systems are of the utmost importance for - fundamental and applied reasons. A general understanding the nature of magnetic quantum phases of matter requires the study of magnetic systems beyond spin-1/2, where more magnetic phases are possible. - - - 2018-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - France - - - Spin1D - - - H2020-MSCA-IF-2015 - - - 701894 - - - - - LEUPHANA UNIVERSITAT LUNEBURG - - - EUR 171 460,80 - - - Social and ecological networks supporting biodiversity and food security - - - EUR 171 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - Halting biodiversity decline and ensuring food security are urgent and interconnected challenges. I will study how social and ecological structures in interaction generate tradeoffs and synergies between food security and - biodiversity conservation. SENet has two aims: A) to identify ecological and socioeconomic structures that benefit or harm food security and biodiversity conservation in a rural, poor study landscape, and B) to develop an integrated network model - capable of predicting such effects in similar settings worldwide. Globally, SENet will be the first research to apply (graph-theoretic) network analysis to understand synergies and tradeoffs in the food security–biodiversity nexus. I will develop the - integrated model using data from a landscape in Ethiopia, where agricultural expansion and human-wildlife conflicts are driving deforestation. SENet differs from existing approaches that concentrate on increasing agricultural output and overlook that - social and ecological outcomes are interdependent and cannot be understood separately. In contrast, my method focuses on the food security of rural villages and on the factors that prompt farmers to clear or to plant forest, to change crops, to - migrate elsewhere, etc., i.e., on farmers' decisions that affect both food security and biodiversity. In this context, I will use systematic network analysis to show how farmers are connected through food trade, knowledge exchange and other - socioeconomic processes, but also how their crop fields are linked to forests and human–wildlife conflicts. The implementation of SENet will draw on my skills in network analysis and the host’s research excellence on the biodiversity of agricultural - landscapes, including their ongoing fieldwork in my study area. This setup ensures a theoretical and empirical foundation for my network models, and a forum for communicating my results to non-academic actors in Ethiopia and Europe. - - 2018-01-14, closed project - - - 2016-01-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - SENet - - - H2020-MSCA-IF-2014 - - - 661780 - - - - - KOC UNIVERSITY - KOC UNIVERSITY - QUEEN MARY UNIVERSITY OF LONDON - - - EUR 1 089 432 - - - Market Selection, Frictions, and the Information Content of Prices - - - EUR 1 089 432 - - - Turkey - Turkey - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project studies information aggregation in multiple-linked auction markets with large numbers of goods and bidders. Past work assumes bidders trade in a single, centralized, frictionless auction market. Instead, I study - bidders with unit demand who decide to purchase one of many possible goods which are on auction in distinct markets. The goods traded in each market are identical, common-value objects and the price is determined by a uniform-price auction. Bidders - receive imperfect signals about the state of the world and select to bid in one of the auction markets. The markets differ in institutional structure and therefore frictions. Market frictions result from imperfect competition, government - interventions, informational frictions, and preference heterogeneity. All such frictions render the gains from trade uncertain. - - 2021-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Turkey - - - INFORMATIVEPRICES - - - ERC-2015-CoG - - - 681460 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 183 454,80 - - - The Role of Circulating Monocytes in the Development of Brain Metastases - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Brain metastases, particularly from breast cancer, are a significant clinical problem. About one fifth of breast - - 2018-02-10, ongoing project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - Brain Metastases - - - H2020-MSCA-IF-2014 - - - 654985 - - - - - ATHENS UNIVERSITY OF ECONOMICS AND BUSINESS - RESEARCH CENTER - - - EUR 82 326,60 - - - Biomedical Information Synthesis with Deep Natural Language Inference - - - EUR 82 326,60 - - - Greece - - - Higher or Secondary Education Establishments - - Deep neural networks (DNNs) have become a critical tool in natural language processing (NLP) for a wide variety of language technologies, from syntax to semantics to pragmatics. In particular, in the field of natural language - inference (NLI), DNNs have become the de-facto model, providing significantly better results than previous paradigms. Their power lies in their ability to embed complex language ambiguities in high dimensional spaces coupled with non-linear - compositional transformations learned to directly optimize task-specific objective functions. We propose to adapt Deep NLI techniques to the biomedical domain, specifically investigating question answering, information extraction and synthesis. The - biomedical domain presents many key challenges and a critical impact that standard NLI challenges do not posses. First, while standard NLI data sets requires a system to model basic world knowledge (e.g., that ‘soccer’ is a ‘sport’), they do not - presume a rich domain knowledge encoded in various and often heterogeneous resources such as scientific articles, textbooks and structured databases. Second, while standard NLI data sets presume that the answer/inference is encoded in a single - utterance, the ability to reason and extract information from biomedical domains often requires information synthesis from multiple utterances, paragraphs, and even documents. Finally, whereas standard NLI is a broad challenge aimed at testing - whether computers can make general inferences in language, biomedical texts are a grounded and impactful domain where progress in automated reasoning will directly impact the efficacy of researchers, physicians, publishers and policy makers. - - 2018-09-30, Grant Agreement terminated - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Greece - - - DNLIBiomed - - - H2020-MSCA-IF-2016 - - - 751722 - - - - - UNIVERSITAET BERN - UNIVERSITAET BERN - - - EUR 1 989 938 - - - Perception of Plant Volatiles - - - EUR 1 989 938 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The capacity to produce and perceive organic chemicals is essential for most cellular organisms. Plant leaves that are attacked by insect herbivores for instance start releasing distinct blends of herbivore-induced plant - volatiles, which in turn can be perceived by non-attacked tissues. These tissues then respond more rapidly and more strongly to herbivore attack. One major question that constrains the current understanding of plant volatile communication is how - plants perceive herbivore induced volatiles. Can plants smell danger by detecting certain volatiles with specific receptors? Or are other mechanisms at play? Answering these questions would push the boundaries of plant signaling research, as it would - allow for the creation of perception impaired mutants to perform detailed analyses of the biological functions and potential agricultural benefits of plant volatile perception. - - - 2022-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Switzerland - - - PERVOL - - - ERC-2016-STG - - - 714239 - - - - - INSTITUT CURIE - INSTITUT CURIE - - - EUR 2 312 500 - - - Exploring mechanisms of gene repression and escape during X-chromosome inactivation - - - EUR 2 312 500 - - - France - France - - - Research Organisations - Research Organisations - - During mammalian development, precise gene expression patterns have to be established and then maintained, or reversed, in different cellular and tissue contexts. A striking example of such developmentally regulated gene - control is X-chromosome inactivation (XCI), whereby one of the two X chromosomes in females is silenced during embryogenesis. XCI is initiated by the non-coding Xist RNA, which coats the chromosome in cis, triggering gene repression, chromatin - changes and chromosomal reorganisation. Although Xist’s regulation has been investigated intensively, less is known about the actual mechanisms underlying the process of chromosome-wide gene silencing that it induces. Indeed, X-linked loci show very - different kinetics of repression during development, implying regional and/or locus specific diversity. Furthermore, some genes avoid or escape XCI altogether, either constitutively or in a tissue or stage-specific fashion, but the molecular basis - for this is unclear. Here we propose to dissect the mechanisms underlying gene regulation during XCI. We will investigate the roles of recently identified Xist partners in gene silencing and perform genetic screens to identify new factors involved in - silencing and escape from XCI. Transcription, chromatin status and chromosome conformation during XCI will be investigated in an allelic-specific manner during precise developmental time windows to pinpoint the critical changes accompanying silencing - and escape. We will use genetic engineering to alter genomic and epigenomic landscapes of selected loci and target candidate trans-acting factors to their putative regulatory elements. Finally, we will develop tools to explore gene expression during - XCI using live cell imaging of embryogenesis. Using this innovative set of approaches, we hope to define both general principles underlying gene silencing and escape in XCI, as well as locus-specific features that could serve as new paradigms for - research in developmental epigenetics. - - 2020-10-31, ongoing project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - France - - - XPRESS - - - ERC-2014-ADG - - - 671027 - - - - - UNIVERSITE DE BORDEAUX - UNIVERSITE DE BORDEAUX - - - EUR 1 500 000 - - - Study on Environmental and GenomeWide predictors of early structural brain Alterations in Young students - - - EUR 1 500 000 - - - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Mounting evidence suggests that early life factors have an important impact on the occurrence of late-life neurological diseases. From a public health perspective this is of particular relevance for dementia, the prevalence of - which is increasing drastically, with no available preventive treatment, and epidemiological data suggesting that pathological processes may begin many years before clinical diagnosis. MRI-defined structural brain phenotypes are powerful intermediate - markers for dementia, and can already show measurable alterations in young and middle-aged adults. These include global and regional brain volumes, gray matter volume and cortical thickness, and markers of white matter integrity. The SEGWAY project - aims to: (i) explore the heritability and genetic determinants of structural brain phenotypes in young adults in their early twenties participating in the i-Share study, the largest ongoing student cohort; (ii) take a lifetime perspective by - examining the shared genetic contribution to structural brain alterations in young adulthood (i-Share) and late-life, among participants of a large French population-based study (3C-Dijon); (iii) explore the interaction between genetic variants and - vascular risk factors with established impact on structural brain phenotypes, in both age groups; (iv) examine the clinical significance of genetic risk variants for structural brain alterations by testing their association with cognitive performance - in young and older adults. Replication and of our findings will be sought in the multigenerational Framingham Heart Study and other independent samples. Identifying common biological mechanisms underlying both early and late-life structural brain - changes would provide important information on the mechanisms and timecourse of brain aging throughout a lifetime and could be of major importance for identifying of molecular drug targets and characterizing high risk populations most likely to - benefit from early interventions. - - 2020-11-30, ongoing project - - - 2015-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - SEGWAY - - - ERC-2014-STG - - - 640643 - - - - - THE UNIVERSITY OF BIRMINGHAM - FUNDACIO INSTITUT DE CIENCIES FOTONIQUES - POLITECNICO DI MILANO - UNIVERSITY COLLEGE LONDON - INSTYTUT BIOCYBERNETYKI I INZYNIERII BIOMEDYCZNEJ PAN - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - PHYSIKALISCH-TECHNISCHE BUNDESANSTALT - UNIVERSITY HOSPITAL BIRMINGHAM NHS FOUNDATION TRUST - FUNDACIO HOSPITAL UNIVERSITARI VALL D'HEBRON - INSTITUT DE RECERCA - PICOQUANT INNOVATIONS GMBH - HEMOPHOTONICS SL - - - EUR 3 835 764,36 - - - Brain injury and trauma monitoring using advanced photonics - - - EUR 3 835 764,36 - - - United Kingdom - Spain - Italy - United Kingdom - Poland - France - Germany - United Kingdom - Spain - Germany - Spain - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Other - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Our vision is to develop a suite of standardised non-invasive devices that will provide essential information about brain health in neurocritical care and neuromonitoring, with a particular emphasis on 1. traumatic brain - injury: the “silent epidemic of the third millennium” and 2. hypoxia in newborn children. Survivors present permanent neurological conditions that have a profound impact on the quality of life of individuals and their families, and hence a large - socio-economic impact. The key factors influencing these conditions and their treatment are the avoidance of brain hypoxia and metabolic disturbances and this is driving the transfer of new neuromonitoring systems to the bedside where they are being - shown to have a transformative effect on patient care. - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - BitMap - - - H2020-MSCA-ITN-2015 - - - 675332 - - - - - COLLEGE DE FRANCE - COLLEGE DE FRANCE - - - EUR 1 959 283 - - - Saadian Intellectual and Cultural Life - - - EUR 1 959 283 - - - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The aim of the interdisciplinary investigation project SICLE is to investigate in a completely new way the intellectual and cultural history of the Saadian period in Morocco (1554-1660), using primarily the Saadian sultans’ - library, exceptionally preserved as a ‘time capsule’ in the El Escorial monastery following king Felipe III’s decision to include it in his own library. The period is a time of direct involvement of Morocco in international politics and exchanges, - both in their East-West (with the Ottoman empire) and North-South (with Europe) dimensions, without forgetting Timbuktu and the Songhay empire conquered by Ahmad al-Mansur, the most brilliant ruler of the dynasty. The manuscripts kept in El Escorial - mirror the interests and the tastes of the Saadian rulers and of the elite at large. The paratextual information they contain (but ignored by the catalogues) like the various notes, the colophons, the illuminations or the bindings will be - systematically collected and analyzed in a trans-disciplinary approach which can be defined as an ‘archaeology of the book’, combining codicology, philology, archaeometry, anthropology and art history. The same approach will be applied to the books - of the ‘ordinary people’ from Saadian times preserved in Moroccan collections. SICLE goals are to offer: a) a history of the Saadian sultans’ library and an analysis of their interests; b) a cultural and intellectual history of Morocco during the - 16th century, with groundbreaking studies on the history of the book, on its economy and on education; c) an evaluation of the relationship with the ‘outside’ (Christian Europe, the Ottoman empire and sub-Saharan Africa) and the possible influence it - had on Saadian intellectual production. Special attention will be paid to the Jewish and Morisco communities in their role of culture brokers. - - 2021-01-31, ongoing project - - - 2016-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - France - - - SICLE - - - ERC-2014-ADG - - - 670628 - - - - - COLLEGE DE FRANCE - COLLEGE DE FRANCE - - - EUR 1 997 497,50 - - - Josephson Junction Spectroscopy of Mesoscopic Systems - - - EUR 1 997 497,50 - - - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Spectroscopy is a powerful tool to probe matter. By measuring the spectrum of elementary excitations, one reveals the symmetries and interactions inherent in a physical system. Mesoscopic devices, which preserve quantum - coherence over lengths larger than the atomic scale, offer a unique possibility to both engineer and investigate excitations at the single quanta level. Unfortunately, conventional spectroscopy techniques are inadequate for coupling radiation to - mesoscopic systems and detecting their small absorption signals. I propose an on-chip, Josephson-junction based spectrometer which surpasses state-of-the-art instruments and is ideally suited for probing elementary excitations in mesoscopic systems. - It has an original design providing uniform wideband coupling from 2-2000 GHz, low background noise, high sensitivity, and narrow linewidth. - - 2020-03-31, ongoing project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - JSPEC - - - ERC-2014-STG - - - 636744 - - - - - HELSINGIN YLIOPISTO - - - EUR 191 325,60 - - - An analyzer for preterm EEG - - - EUR 191 325,60 - - - Finland - - - Higher or Secondary Education Establishments - - Compromised early brain development leads to lifelong disabilities, which have a heavy impact on the child, families, as well as society as a whole. Advances in clinical care have led to an increasing number of babies - surviving extreme prematurity. The global challenge is to avoid early brain injuries by optimizing neurological care during the early days of neonatal intensive care. This aim necessitates the use of constant, cot-side brain monitoring using the - electroencephalograph (EEG), which faces formidable logistic challenges due to the need for large scale data analysis by EEG experts. The only imaginable solution for dealing with the vast amount of EEG information is to automate EEG analysis. This - action proposes the development of an original, automated, cot-side Analyser for Preterm EEG (APE). This algorithm will be based on the combination of state of the art biomedical signal processing techniques and recent advances in basic developmental - neuroscience. An accurate cot side EEG analyser has strong clinical potential for improving early brain care, leading to lifelong improvements in affected individuals as well as unprecedented opportunities to benchmark new brain interventions. The - project will significantly develop the applicant’s career by adding new domains of human neurophysiology and basic neuroscience, bio-signal analysis, as well as conduct of international research projects to his skillset. His secondment to a - well-established Finnish SME in the field, MegaEMG, will provide insight into the development of medical devices, commercialization, and regularity environment. The technology developed in this project is translatable into medical devices, providing - an opportunity to enhance Europe’s status as a market leader in brain monitoring devices, as well as University of Helsinki’s standing as a centre of excellence for neonatal neurophysiology. - - 2017-08-31, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Finland - - - APE - - - H2020-MSCA-IF-2014 - - - 656131 - - - - - COLLEGE DE FRANCE - COLLEGE DE FRANCE - - - EUR 2 000 000 - - - Wiring synaptic circuits with astroglial connexins: mechanisms, dynamics and impact for critical period plasticity - - - EUR 2 000 000 - - - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Brain information processing is commonly thought to be a neuronal performance. However recent data point to a key role of astrocytes in brain development, activity and pathology. Indeed astrocytes are now viewed as crucial - elements of the brain circuitry that control synapse formation, maturation, activity and elimination. How do astrocytes exert such control is matter of intense research, as they are now known to participate in critical developmental periods as well - as in psychiatric disorders involving synapse alterations. Thus unraveling how astrocytes control synaptic circuit formation and maturation is crucial, not only for our understanding of brain development, but also for identifying novel therapeutic - targets. - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - France - - - AstroWireSyn - - - ERC-2015-CoG - - - 683154 - - - - - COLLEGE DE FRANCE - COLLEGE DE FRANCE - - - EUR 1 483 143,75 - - - Morphogenesis and Molecular Regulation of Colour Patterning in Birds - - - EUR 1 483 143,75 - - - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Animals display a tremendous diversity of patterns ‒from the colourful designs that adorn their body to repeated segmented appendages. Natural patterns result from the formation of discrete domains within developing tissues - through the integration of positional cues by cells that consequently adopt specific fates and produce spatial heterogeneity. How can such developmental processes underlie the apparent complexity and diversity of natural patterns? We propose to - address this long-standing question with an innovative experimental design: we will make use of natural variation as a powerful tool to facilitate the identification of patterning molecules and morphogenetic events. We will study colour pattern, a - crucial adaptive trait that varies extensively in nature, from large colour domains to periodic designs. In amniotes, colour pattern is formed by spatial differences in the distribution of pigment cells and integumentary appendages. While the - pigmentation system has been well characterized, the mechanisms governing the formation of compartments in the skin of wild animals have remained unclear, largely because laboratory models do not display ecologically-relevant colour patterns. We will - use a combination of forward genetics, developmental biology, modelling, and imaging to study natural variation in the large colour domains of Estrildid finches and the periodic stripes of Galliform birds. For both phenotypes, we will characterize - the organization of the embryonic skin and the mode of patterning (i.e., instructional patterning via external cues vs locally-occurring self-organization) underlying their formation, and identify the molecular factors and developmental processes - contributing to their variation. Results from these studies will elucidate the biochemical events and tissue rearrangements orchestrating colour patterning in development and shed light on how these processes shape natural variation in this trait‒ - and more generally, in natural patterns. - - 2020-04-30, ongoing project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - COLOUR PATTERN - - - ERC-2014-STG - - - 639060 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 195 454,80 - - - An induced pluripotent stem cell-based neuronal model of Spinocerebellar ataxia - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The spinocerebellar ataxias (SCAs) are a diverse group of neurological disorders defined by a loss of motor coordination. No effective treatments exist, and there is thus a pressing need for suitable models in which to study - disease progression and to screen potential therapies. Induced pluripotent stem cells (iPSCs), which are capable of differentiation into any cell type of the body, offer the opportunity to study neurodegeneration in vitro. The proposed study aims to - be the first in Europe to establish an iPSC-derived model of cerebellar disease, focusing on two genetic subtypes of SCA - SCA14 and 41. Increasing evidence points towards common pathological pathways shared across multiple SCA subtypes, which could - provide novel therapeutic targets. There is also evidence to suggest that abnormalities in Purkinje cell development may contribute to the pathogenesis of the SCAs. This model will thus be used to elucidate the molecular mechanisms underlying common - SCA-causing disease pathways, and to unravel the neurodevelopmental aspects of these diseases, in order to develop early-intervention therapies. Preliminary results indicate successful differentiation of iPSCs into cerebellar progenitor cells, using - a protocol I have optimised. Following terminal differentiation, these cells will be investigated for common disease phenotypes and developmental defects, using a combination of transcriptomic, biochemical, and electrophysiological methods. Results - will be validated by comparison with post-mortem brain samples and ataxic mouse models. By adapting this differentiation strategy to a format amenable to high-throughput screening, a pipeline will be established for the identification of novel - therapeutic compounds. This groundbreaking study will enable the investigation of mechanisms which render the cells of the cerebellum particularly sensitive to degeneration, as well as providing a platform for pre-clinical screening of therapeutics - for neurodegenerative conditions. - - 2018-06-30, ongoing project - - - 2016-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - iPSCAtaxia - - - H2020-MSCA-IF-2015 - - - 699978 - - - - - WISSENSCHAFTSZENTRUM BERLIN FUR SOZIALFORSCHUNG GGMBH - - - EUR 159 460,80 - - - International Authority and Intellectual Domination: External Donors and Local Organizations in Latin American Social Sciences (1945-1973). - - - EUR 159 460,80 - - - Germany - - - Research Organisations - - Scholars interested in Global Governance and international authority favour a broadly Weberian idea of legitimacy as the explanation for the stability and effectiveness of international authority. However, I expand here the - focus of analysis in order to include additional concepts like “commonality of interests” and “means of domination”, which are crucial for Weber, but absent from the IR literature on international authority. Among the means of domination, knowledge - is of particular importance because it distinguishes the rational from the other types of domination, which explains why knowledge, experts, and diplomats have become an increasingly important topic for IR scholars interested in organizations and in - authority. The potential consequences of international authority at local level, like resistance and protection, also receive their due consideration. To put it in a nutshell, what this project pretends is to offer a better account of how donor - organizations transfer knowledge, money, goods, salaries to local organizations like universities and research centres, purportedly with the intention of making possible for recipients to pursue their educative policies goals and policies. In - reality, I submit, these are “means of domination” that foundations and IOs award local actors so that they operate teaching programs and research projects chosen by the patrons or, in other words, in order to move local actors to collaborate in - realizing the goals of donors. In empirical terms, the question is to what extent international organizations – UNESCO, ONU – and transnational ones – philanthropic foundations like Rockefeller and Ford – succeed or failed in their efforts to wield - influence on academic organizations, more specifically on teaching and research in the social sciences, in Latin America during the post-war years (1945-1973). - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Germany - - - PHILANTHROPIC RULE - - - H2020-MSCA-IF-2015 - - - 702562 - - - - - COLLEGE DE FRANCE - - - EUR 185 076 - - - Topological superfluidity in ultracold gas of Dysprosium atoms - - - EUR 185 076 - - - France - - - Higher or Secondary Education Establishments - - In the last decade experimental and theoretical studies in condensed matter demonstrated that materials with strong spin-orbit coupling can host a new state of matter for the electron gas - a topological insulator. More - recently the concept of topological matter was generalized theoretically to superconducting systems with strong spin-orbit coupling. The topological character manifests itself in the presence of quantum states bound to edges or defects that exhibit - exotic physical properties. In topological superconductors, edge states are described as Majorana fermions. These exotic particles - originally predicted in high-energy physics - are non-abelian anyons: their quantum statistics is neither bosonic nor - fermionic. Observing Majorana fermions would be the first demonstration of such exotic particles. The field of ultracold atoms seems well suited for the realization of superfluid systems with strong spin-orbit coupling. As shown in recent - experimental works, manipulating manipulating atomic internal states with lasers can mimick spin-orbit couplings of strong amplitude. We have constructed at College de france a new experimental setup producing ultracold Dysprosium atomic gases. This - atomic species exhibits narrow electronic transitions that should allow one to create such a spin-orbit coupling without substantial heating, which is the main requisite for creating a superfluid state. Combining spin-orbit coupling and strong - interactions should lead to the formation of a topological superfluid. We will investigate the structure of quasi-particle excitations of this superfluid, which should exhibit edge modes described as Majorana fermions. - - 2017-04-30, closed project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - Topological superfluidity - - - H2020-MSCA-IF-2014 - - - 661433 - - - - - TECHNOLOGIKO PANEPISTIMIO KYPROU - UNIVERSITA DEGLI STUDI ROMA TRE - ARISTOTELIO PANEPISTIMIO THESSALONIKIS - UNIVERSITY COLLEGE LONDON - TELEFONICA INVESTIGACION Y DESARROLLO SA - SIGNALGENERIX LTD - INNOVEITORS (INNOVATORS) EFARMOGES YPSILIS TECHNOLOGIAS AE - CY.R.I.C CYPRUS RESEARCH AND INNOVATION CENTER LTD - LSTECH LTD - - - EUR 2 160 000 - - - EnhaNcing seCurity And privacy in the Social wEb: a user centered approach for the protection of minors - - - EUR 2 160 000 - - - Cyprus - Italy - Greece - United Kingdom - Spain - Cyprus - Greece - Cyprus - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - ENCASE will leverage the latest advances in usable security and privacy to design and implement a browser-based architecture for the protection of minors from malicious actors in online social networks. The ENCASE user-centric - architecture will consist of three distinct services, which can be combined to form an effective protective net against cyberbullying and sexually abusive acts: a) a browser add-on with its corresponding scalable back-end software stack that collects - the users’ online actions to unveil incidents of aggressive or distressed behavior; b) a browser add-on with its associated scalable software stack that analyses social web data to detect fraudulent and fake activity and alert the user; and c) a - browser add-on that detects when a user is about to share sensitive content (e.g., photos or address information) with an inappropriate audience and warns the user or his parents of the imminent privacy threat. The third add-on has usable controls - that enable users to protect their content by suggesting suitable access lists, by watermarking, and by securing the content via cryptography or steganography. The three browser add-ons and the back-end social web data analytics software stack will - be assessed with user studies and piloting activities and will be released to the public. The foundation of the research and innovation activities will be a diligently planned inter-sectorial and interdisciplinary secondment program for Experienced - and Early Stage Researchers that fosters knowledge exchange. The academic partners will contribute know-how on user experience assessment, large scale data processing, machine learning and data-mining algorithm design, and content confidentiality - techniques. The industrial partners will primarily offer expertise in production-grade software development, access to real-world online social network data, and access to numerous end-users through widely deployed products. - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Cyprus - - - ENCASE - - - H2020-MSCA-RISE-2015 - - - 691025 - - - - - UNIVERSITE DE MONTPELLIER - - - EUR 185 076 - - - Venomics In Predator-prey Systems - - - EUR 185 076 - - - France - - - Higher or Secondary Education Establishments - - Marine invertebrates are a rich source of bioactive compounds, including complex venoms that are highly effective and specific, having evolved through million years of natural selection. Despite their potential for drug - discovery, chemical diversity of animal venoms is largely uncharacterized. Recent venomics research led to important technological advances: it is time for an expansion to neglected organisms that could lead to the discovery of compounds with novel - biological activities. The main goal of VIPS Project is to address the biochemical diversification of two previously untapped marine predator-prey systems involving an Anthozoan and a corallivorous snail, both producing toxic secretions. The - Researcher will be integrated into the research environment of the Université de Montpellier, where the integration of different research fields (including genomics, proteomics, molecular evolution, peptide synthesis, and electrophysiology) will be - used to discover and functionally characterize new bioactive compounds, define their interactions, highlight their evolutionary role and, through secondment, valorise their applicative potential. Focusing on venomous predator-prey couples is an - innovative approach that will facilitate the identification of biological activity and evolutionary role of venom components. Wide diffusion of the VIPS Project will be ensured through open access to publications and data, and a variety of - communication activities for the lay public that will exploit the appeal of predator-prey systems to highlight the link between basic and applied research. The activities of VIPS Project perfectly complement the background of the Researcher, allowing - the achievement of full control over all stages of venomics research, and the development of new transferable skills that will foster her career. VIPS goals are highly relevant to Horizon2020, including the discovery of more efficient and specific - drugs and the development of marine biotechnologies. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - VIPS - - - H2020-MSCA-IF-2016 - - - 748902 - - - - - ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA - - - EUR 159 034,56 - - - NEURODIVERSITY BETWEEN LAW AND SCIENCE - - - EUR 159 034,56 - - - Italy - - - Higher or Secondary Education Establishments - - The aim of the research proposal “Neurodiversity between Law and Science” (NEDBELS) is to inquire into the legal impacts and socio-political implications of the concept of neurodiversity. This term pertains to individuals - diagnosed with neurodevelopmental disorders such as Asperger’s Syndrome and Autism and hypothesizes the emergence of a new category of difference in the human population. NEDBELS explores how this concept challenges the constitutional principle of - equality, as well as how it fosters the need to accommodate new principles in criminal and civil law. This proposal has risen from a need for heightened communication between law and science. Scientific theories, concepts and methods widely permeate - law and adjudication, and legal and ethical frameworks intimately drive applied sciences, as in education and health care systems. Therefore, one might reasonably expect that these two worlds would cooperate on a regular basis. However, lawyers, - scientists and health care professionals operate largely insulated from one another in research, formal training and daily practice. This divergence prevents vulnerable minorities, such as people with neurodevelopmental disorders, from reaping the - full socio-political potential of scientific advancements. NEDBELS’s goal is to increase communication between law and neurosciences through interdisciplinary research methodologies and scientific training-through-research as well as by enhancing the - synergy among legal experts, policy makers and scientists in the field of neurodiversity - - 2018-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Italy - - - NEDBELS - - - H2020-MSCA-IF-2014 - - - 656988 - - - - - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - AUDYSSEY LABORATORIES INC - - - EUR 254 457 - - - CAPTURING AND REPRODUCTION OF CROWDED ACOUSTIC ENVIRONMENTS FOR IMMERSIVE APPLICATIONS - - - EUR 254 457 - - - Greece - United States - - - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - CROWDMERSE enables real-time capture, processing, and reproduction of an immersive audio experience to the user of any event of interest, focusing on “crowded” acoustic events. Acoustic scenes with large audiences, such as - sports events or music concerts, present significant challenges for immersive reproduction which have not been so far adequately considered in the signal processing community. Technological breakthrough in sports events broadcasting has a strong - potential impact on media providers, and consequently on the European and global economy. The challenges of capturing and reproducing crowded acoustic events include the need to spatially capture and reproduce numerous sound sources, such as the - applause and yells of the spectators, in addition to the “main” sounds of the event. Concerns regarding the privacy of the spectators must not be overlooked: the conversations of the audience members sitting near the microphone sensors must be - eliminated. In order to spatially sample large venues, the acoustic sensors should be low-cost, small-sized, and support wireless operation. The developed algorithms should respect the limited sensor resources, while operating in real-time to enable - commercial applications. Our final objective is to enable real-time delivery of crowded acoustic events so that the designed platform can be integrated with today’s High-Definition TV programs. CROWDMERSE focuses on sound capturing using multiple - closely placed microphones forming a microphone array. The audio content is rendered through a home entertainment system equipped with multiple loudspeakers, accompanying the content of a typical HDTV broadcast. Addressing the scientific challenges - and proposing a solution which can be integrated with current broadcasting principles is guaranteed given the previous involvement of the experienced researcher in sports broadcasting projects. The proposed methods are expected to have impact in the - general area of immersive sound environments. - - 2020-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Greece - - - CROWDMERSE - - - H2020-MSCA-IF-2016 - - - 745677 - - - - - UNIVERSITAETSKLINIKUM AACHEN - UNIVERSITAETSKLINIKUM AACHEN - - - EUR 145 312 - - - Companion Nanodiagnostics for Quantifying EPR and Stratifying Patients to Targeted Nanotherapies - - - EUR 145 312 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - CONQUEST aims to commercialise a first-of-its-kind platform technology for imaging a biological effect – i.e. the EPR effect – that is predictive for a cancer patient's response to tumor-targeted nanomedicine (NM) therapy. - CONQUEST thereby addresses a key issue in the (nano)pharmaceutical industry; as currently large proportions of cancer patients do not respond to NM, while others show major improvements in terms of response rates, survival times and quality of life. - This trend impairs the outcome of clinical studies and results in many patients receiving treatments that are not effective to them. It would therefore be highly desirable to stratify responders from non-responders prior to study entry or treatment. - CONQUEST stands at the basis of introducing a solution to this problem in the pharmaceutical industry. - - - 2017-06-30, closed project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2015 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Germany - - - CONQUEST - - - ERC-2015-PoC - - - 680882 - - - - - INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM - - - EUR 160 800 - - - Pulsed plasma technology for 2D materials integration - - - EUR 160 800 - - - Belgium - - - Research Organisations - - Atomically thin layers of transition metal dichalcogenides (TMD) are gaining increasing attention as new materials for future Beyond-CMOS electronics. Recently, a great progress has been made in deposition of high quality - layers of TMDs paving the way towards wafer scale device manufacturing. However, many fundamental and technological challenges still have to be addressed. Precise tuning of the number of layers, doping, surface functionalization and selective low - damage etching of TMDs are among the most critical technological steps. Plasma processing is an enabling technology used for doping, etching and deposition of ultrathin layers in microelectronics industry. However, the application of plasmas for - integration of 2D materials remains marginal and poorly controlled. The major challenge for plasma treatment of atomically thin materials is the need for unprecedented control of fluxes and energies of plasma species at the substrate. Pulsed plasma - technology holds promise of reaching conditions required for low damage processing of 2D materials with a single atomic layer precision. The ambition of PULSE2D is to develop highly controlled pulsed-plasma technology for integration of TMDs in - nano-electronic devices on a wafer-scale. A fundamental study of the mechanisms of interaction between pulsed plasmas and atomically thin TMD materials will be performed. Defect production, adsorption and etching processes will be quantified as a - function of plasma parameters. This information will be used to perform atomic layer etching, functionalization and defect healing of TMDs using pulsed plasmas. The research and training activities will enhance technical skills of the candidate in - the emerging area of plasma processing of 2D materials, industry-relevant nano-fabrication and measurement of TMDs transport characteristics. High fundamental and technological interest and timeliness of this subject will provide a powerful thrust - for the future research career of the candidate. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Belgium - - - PULSE2D - - - H2020-MSCA-IF-2016 - - - 752164 - - - - - STICHTING VUMC - STICHTING VUMC - STICHTING VU - - - EUR 150 000 - - - GlioDx - Blood platelet-based monitoring and treatment optimisation for glioblastoma patients - - - EUR 150 000 - - - Netherlands - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Glioblastoma (GBM) is a devastating primary brain cancer which affects about 230.000 people annually. The choice for treatment depends on the subtype of GBM. An accurate detection of tumour subtype is therefore essential for a - personalised targeted treatment. Diagnosis, classification and treatment monitoring occurs currently by radiology and repeated invasive biopsies. There is a need for non-invasive, actionable biomarkers for early-stage diagnosis and disease - monitoring. - - 2018-02-28, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2015 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Netherlands - - - GlioDx - - - ERC-2015-PoC - - - 713727 - - - - - ECOLE CENTRALE DE NANTES - ECOLE CENTRALE DE NANTES - - - EUR 150 000 - - - Industrialization of software and libraries for crack propagation in material and structures using the Thick Level Set method - - - EUR 150 000 - - - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The understanding and the reliable prediction of material degradation, crack initiation and propagation is of vital importance in engineering. It allows the evaluation of product lifecycle and the criticality of exceptional - loads. Also, it enables maintenance optimization in a wide range of industries (automotive, aircraft, nuclear…). Thanks to the ERC “XLS” grant, a new approach coined TLS (“Thick Level Set”) was developed to simulate crack propagation from sane - material to critical rupture. The main advantage of this approach is that it takes into account both crack initiation and crack propagation without mesh size or mesh orientation dependency. This combination is not currently available in the industry. - - 2019-02-28, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - France - - - MATCRACK - - - ERC-2017-PoC - - - 766820 - - - - - UNIVERSITY OF STRATHCLYDE - UNIVERSITY OF GLASGOW - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSITA DEGLI STUDI DI MILANO - WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER - EBERHARD KARLS UNIVERSITAET TUEBINGEN - UNIVERSITAT DES SAARLANDES - Eidgenössische Technische Hochschule Zürich - UNIVERSITAET INNSBRUCK - M-SQUARED LASERS LIMITED - TOPTICA PHOTONICS AG - HOLOEYE PHOTONICS AG - - - EUR 3 893 423,76 - - - Collective effects and optomechanics in ultra-cold matter - - - EUR 3 893 423,76 - - - United Kingdom - United Kingdom - France - Italy - Germany - Germany - Germany - Switzerland - Austria - United Kingdom - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Corinna Hahn - Tel.: +49 681 95 92 3362 - Fax: +49 681 95 92 3370 - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The network “Collective effects and optomechanics in ultra-cold matter” (ColOpt) will train early-stage researchers (ESR) in fundamental science and applications in the areas of cold atom and quantum physics, optical - technologies and complexity science to promote European competiveness in emergent quantum technologies. It consists of nine academic nodes and three companies from six European countries, supported by two partners in Brazil and the USA, five further - non-academic partners and one public-private partnership. - - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - ColOpt - - - H2020-MSCA-ITN-2016 - - - 721465 - - - - - CONSIGLIO NAZIONALE DELLE RICERCHE - MEDITERRANEAN AGRONOMIC INSTITUTE OF CHANIA - INSTITUT NATIONAL D'ETUDES SUPERIEURES AGRONOMIQUES DE MONTPELLIER - UNIVERSITA DEGLI STUDI DI PERUGIA - AGRICULTURAL UNIVERSITY OF ATHENS - INSTITUTO ANDALUZ DE INVESTIGACIONY FORMACION AGRARIA PESQUERA ALIMENTARIA Y DE LA PRODUCCION ECOLOGICA - CONFEDERAZIONE ITALIANA AGRICOLTORI REGIONALE UMBRIA - SYNDESMOS BIOMHCHANON TYPOPOIHTON EXAGOGON ELAIOLADOY - OPTIMUM QUALITY SL - - - EUR 1 296 000 - - - Bioresources For Oliviculture - - - EUR 1 296 000 - - - Italy - Greece - France - Italy - Greece - Spain - Italy - Greece - Spain - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Other - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The project aims at establishing a multi-lateral network of research and innovation staff active in olive germplasm access, conservation, evaluation and exploitation, strengthening research capacities through the exchange of - knowledge and expertise on a shared research programme focused on developing integrated common protocols to phenotype and characterize plants at molecular, morphological and physiological level, and evaluating the olive oil quality related to - varieties. The scientific results of the project will contribute at improving the potential of the olive germplasm collections, repositories and banks as main sources of variability and of the evaluation tools to be used to increase oliviculture - sustainability. Particular attention will be paid to issues concerned to international intellectual property rights for conserving, exchanging and using the olive genetic resources. Another aim is to create a long lasting network among partners also - promoting new common projects in the frame of Horizon2020 and other international funding sources. The joint exchange programme will involve 9 beneficiaries and 6 partners belonging to AC and NAC sectors and will be performed through a series of - short and long term staff exchanges and workshops among European (Italy, Spain, Greece and France) and third countries (Morocco, Lebanon, Jordan, Argentina, Chile and Mexico). The International Olive Council (IOC), represented by IOC Executive - Director, Jean-Louis Barjol, expressed its strong support to “BeFOre” planning to play an important role in dissemination activities. Experienced and early stage researchers, technicians and managers, are expected to be exchanged between EU and TC to - ensure a good scientific transfer of knowledge and training. Enhancement of careers for the staff involved is expected. The project coordination and management will be ensured by the contribution of a well established coordination group and a - Steering Committee. - - 2019-01-31, ongoing project | - - - 2015-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Italy - - - BeFOre - - - H2020-MSCA-RISE-2014 - - - 645595 - - - - - AKZO NOBEL CHEMICALS BV - - - EUR 165 598,80 - - - Better tools for combating insect borne diseases by understanding influences on the fate of common pesticides in paint formulations - - - EUR 165 598,80 - - - Netherlands - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Malaria, Zika virus, dengue fever and yellow fever are mosquito transmitted diseases for which a vaccines either do not exists or are not widely available. Prevention control is the main way to reduce their spread, and the use - of insecticides constitutes one of the key measures recommended by World Health Organisation. New innovative methods of bringing the insects into contact with the insecticides include the development of insecticidal paint with the advantage of safer - application, targeted dosing and significantly reduced risk of collateral damage to humans and the environment. This project will address some of the challenges in developing these solutions. - - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-SE - Society and Enterprise panel - - - Netherlands - - - ChiPyrNMR - - - H2020-MSCA-IF-2016 - - - 749083 - - - - - KUNGLIGA TEKNISKA HOEGSKOLAN - KUNGLIGA TEKNISKA HOEGSKOLAN - - - EUR 1 500 000 - - - Distributed and Dynamic Graph Algorithms and Complexity - - - EUR 1 500 000 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project aims to (i) resolve challenging graph problems in distributed and dynamic settings, with a focus on connectivity problems (such as computing edge connectivity and distances), and (ii) on the way develop a - systematic approach to attack problems in these settings, by thoroughly exploring relevant algorithmic and complexity-theoretic landscapes. Tasks include - - 2022-01-31, ongoing project - - - 2017-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Sweden - - - DisDyn - - - ERC-2016-STG - - - 715672 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 148 375 - - - Electrochemical Testing Platform for Advanced Energy Materials - - - EUR 148 375 - - - France - France - - - Research Organisations - Research Organisations - - "Throughout history, the Li-ion battery technology has relied on cationic redox reactions as the sole source of energy storage capacity. This is no longer true since 2013, where our group had demonstrated that Li-driven - reversible formation of (O2)n peroxo-groups in new layered oxides led to extraordinary increases in energy storage capacity. To fully exploit this discovery we were granted in 2015 an advanced ERC grant entitled ""Anionic redox processes: A - transformational approach for advanced energy materials (ARPEMA)"", the goal being to rationalize the fundamental science underpinning this new concept. This calls for new paradigms in characterization techniques to fully track among others the - stability of these new compounds as well as the side reactions that they could generate at both electrodes during cycling together with their transport and kinetic properties. To address this critical need we developed a new design test system which - enables for monitoring potential, current, temperature, pressure as well as the nature and composition of the released gases together with the impedance built-up at each electrode. Owing to the relative simplicity, high versatility and great - reliability of such a new-patented multi-function testing device we anticipate its rapid implementation to various battery technologies. The goal of this project is to develop a proof of concept prototype and a small series production, as well as - performing an extensive market analysis and budgeting suppliers, all for establishing an accurate business proposition. This information will be consolidated in a business plan and will be used in the creation of a company together with potential - investors. We believe that this device will enable a rapid development of the next generation of high energy density batteries and consists in a global market commercial opportunity." - - 2018-12-31, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - France - - - EMPhAsIS - - - ERC-2016-PoC - - - 755456 - - - - - TECHNISCHE UNIVERSITAT DARMSTADT - TECHNISCHE UNIVERSITAT DARMSTADT - - - EUR 2 499 789 - - - A Global History of Technology, 1850-2000 - - - EUR 2 499 789 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - What role did technology play in the age of colonization and globalization? The proposed project, A Global History of Technology, 1850-2000 (GLOBAL-HOT), explores this vital question. - - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - GLOBAL-HOT - - - ERC-2016-ADG - - - 742631 - - - - - UNIVERSITY COLLEGE LONDON - UNIVERSITY COLLEGE LONDON - - - EUR 1 500 000 - - - Neurocognitive mechanisms of inhibitory control training and transfer effects in children - - - EUR 1 500 000 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Inhibitory control refers to the ability to control behavioural impulses and is critical for cognitive development. It has been traditionally thought of as a stable trait across the lifespan but recent insights from cognitive - neuroscience show prolonged changes in brain regions that support inhibitory control indicating greater malleability than previously believed. Because childhood inhibitory control predicts well-being later in life this suggests exciting opportunities - for enhancing inhibitory control. I build on highly promising pilot results and draw on a recent neurocognitive model of inhibitory control to test 1) if inhibitory control can be enhanced during childhood, 2) if this transfers onto other domains - important for healthy psychological development such as prosocial- and patient decision-making and academic achievement and 3) which factors predict training success. Children aged 5 to 10 years will undergo 8 weeks of inhibitory control training, - which is a critical duration for observing prolonged training effects and be compared to a group undergoing active sham-training of comparable stimuli and duration but without inhibition. I will assess training effects on the brain and look at - transfer effects onto other domains such as other executive functions, prosocial- and patient decision-making and academic achievement, both immediately and 1 year after training. I expect training to 1) improve inhibitory control, 2) transfer onto - performance on above-mentioned domains and 3) elicit neural changes indicating the effectiveness of training for re- and proactive control. I also expect that individual differences in inhibitory control ability and associated brain regions prior to - training will predict training success. The proposed research has the potential to generate a new and ground-breaking framework on early malleability of inhibitory control with implications for interventions at the time point of greatest likely - impact. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - DEVBRAINTRAIN - - - ERC-2016-STG - - - 715282 - - - - - UNIVERSITY COLLEGE LONDON - UNIVERSITY COLLEGE LONDON - - - EUR 148 550 - - - A neural network builder with remotely controlled parallel computing - - - EUR 148 550 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Neural network simulations have been a driving force behind our advances in the artificial intelligence filed, but also a key tool in our understanding of the human brain. However, exploring such networks usually engages - substantial computational resources requiring specific programing skills and dedicated facilities. In our main project NETSIGNAL, we have developed computational environment ARACHNE aiming to facilitate high-end neural network exploration among - scientific and industrial users. ARACHNE enables an investigator to construct and explore cellular networks of arbitrary biophysical and architectural complexity using a simple interface on a local computer or a mobile device. Through small-file - exchange via the internet, the interface controls a pre-configured computational kernel installed on a remote computer cluster or cloud. Uniquely, ARACHNE can integrate traditional wired network connections with diffuse, volume-transmitted type of - inter-cellular signalling, to reflect the emerging role of glia in brain processing. ARACHNE thus affords a flexible neural network design and incorporates latest advances in neuroscience while providing a portable console suitable for IT-untrained - explorers. ARACHNE has passed a feasibility and novelty test by independent experts (Aleksin et al, PLoS Comp Biology 2017, in press), its test version is available on-line (https://github.com/LeonidSavtchenko/Arachne/). Our goal here is to determine - market potential and the commercial viability of ARACHNE and its conceptual design, but also to establish industry-standard provisions for its commercial exploitation. We plan: (a) to upgrade ARACHNE technical specs, interface, support, etc. to the - industry standard; (b) to assess the market and the competitors; (c) to determine IPR position and strategy, (d) to explore budgeting and further funding strategy, (e) to establish initial provisions for its distribution and/or licensing of ARACHNE. - - 2019-02-28, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - NEUROCLOUD - - - ERC-2017-PoC - - - 767372 - - - - - INSTITUT JOZEF STEFAN - INSTITUT JOZEF STEFAN - CENTER ODLICNOSTI NANOZNANOSTI IN NANOTEHNOLOGIJE - NANOCENTER, LJUBLJANA - - - EUR 149 452 - - - Ultrafast charge density wave memory for quantum computing - - - EUR 149 452 - - - Slovenia - Slovenia - Slovenia - - - Research Organisations - Research Organisations - Research Organisations - - The goal of the PoC is to take a newly discovered phenomenon in quantum electronic materials into a potentially disruptive memory technology offering unprecedented high speed, low energy consumption combined with low - temperature operation. With the PoC grant we aim to establish: - - - 2018-12-31, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Slovenia - - - Umem4QC - - - ERC-2017-PoC - - - 767176 - - - - - UNIVERSITAT DES SAARLANDES - CONSIGLIO NAZIONALE DELLE RICERCHE - FONDAZIONE IRCCS ISTITUTO NEUROLOGICO CARLO BESTA - COLLEGE DE FRANCE - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - UNIVERSITAETSKLINIKUM BONN - Academisch Medisch Centrum bij de Universiteit van Amsterdam - CARDIFF UNIVERSITY - ASTON UNIVERSITY - OSLO UNIVERSITETSSYKEHUS HF - NPI ELECTRONIC GESELLSCHAFT FUER MESS- UND REGELSYSTEME MBH - H. Lundbeck A/S - - - EUR 3 924 324,72 - - - Training, Research and Raising of Public Awareness in Cell Biology and Pathology of Neuroglia - - - EUR 3 924 324,72 - - - Germany - Italy - Italy - France - France - Germany - Netherlands - United Kingdom - United Kingdom - Norway - Germany - Denmark - - - Higher or Secondary Education Establishments - Corinna Hahn - Tel.: +49 681 95 92 3362 - Fax: +49 681 95 92 3370 - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The research in which the young scientists of the EU-GliaPhD consortium will be trained is centred on the role of neuron-glia interactions in brain function and pathology. - - 2020-11-30, ongoing project - - - 2016-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - EU-GliaPhD - - - H2020-MSCA-ITN-2016 - - - 722053 - - - - - TECHNISCHE UNIVERSITAET DRESDEN - TECHNISCHE UNIVERSITAET DRESDEN - - - EUR 2 380 425 - - - Designer recombinases for efficient and safe genome surgery - - - EUR 2 380 425 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Recent breakthroughs in the field of genome editing provide a genuine opportunity to establish innovative approaches to repair DNA mutations to replace, engineer or regenerate malfunctioning cells in vitro or in vivo. However, - most of the recently developed technologies introduce double-strand DNA breaks at a target locus as the first step to gene correction. These breaks are subsequently repaired by one of the cell intrinsic DNA repair pathways, typically inducing an - abundance of insertions and deletions (indels). Ideally, for many applications genome editing should, however, be efficient and specific, without the introduction of indels. Site-specific recombinases (SSRs) allow precise genome editing without - triggering endogenous DNA repair pathways and possess the unique ability to fulfill both cleavage and immediate resealing of the processed DNA in vivo. However, customizing the DNA binding specificity of SSRs is not straightforward. With this - project, we propose to solve this shortcoming. We have already demonstrated that by applying substrate-linked directed evolution, SSRs can be generated that specifically recognize therapeutic targets. The objective of this project is the development - of a universal genome editing platform that allows flexible, efficient and safe gene corrections in cells of any origin without triggering cell intrinsic DNA repair. GenSurge aims to: i) sequence an unprecedented, comprehensive compendium of evolved - SSRs to understand the directed molecular evolution process at nucleotide resolution; ii) integrate the knowledge obtained in i) to develop a unique SSR-based approach to correct genomic inversions; iii) develop a universal SSR-based strategy that - allows flawless, precise and safe genome editing to correct any gene defect in human, animal or plant cells. The successful implementation of this project will deliver a comprehensive, safe and efficient platform from which genome surgery-based cure - strategies can be initiated. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - GENSURGE - - - ERC-2016-ADG - - - 742133 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 276 107,40 - - - The Nexus: an experimental system to study marine larval dispersal - - - EUR 276 107,40 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Dispersal is a fundamental trait for the ecological and evolutionary dynamics of any given species. In marine systems, the primary means of connectivity among fragmented habitats is pelagic larval dispersal (LD). Due to the - inherent difficulty of tracking minute larvae in the ocean, we are still lacking critical insights into the internal and external causes and consequences of LD. Here, we propose the development of an experimental infrastructure, the Nexus, composed - of 25 interconnected larval rearing/settlement tanks, designed to study larval movements as a model of dispersal. We aim to use the Nexus framework to investigate central questions in LD theory that, up to this point, have been difficult to assess: - (1) Do marine organisms exhibit condition-dependent dispersal strategies? (2) If so, how does the interaction of phenotype and environment affect dispersal behaviours (context-dependence)? (3) How will climate change affect condition- and - context-dependent dispersal in offspring via parental effects? These are timely issues to address, as a better understanding of the underlying mechanisms regulating LD will help predict species’ responses to rapid environmental change. The intended - framework will facilitate the holistic assessment and controlled manipulation of the entire LD process, from the natal environment to post-settlement selection, thereby paving the way for novel research avenues in aquatic dispersal ecology. Each tank - in the network can independently be controlled for the type of habitat it provides and corridors can flexibly be opened, closed or made directionally permeable. The versatility of the Nexus offers a high degree of experimental flexibility and control - to address key issues in spatial meta-population ecology. - - 2020-02-17, ongoing project - - - 2017-02-18 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - Nexus - - - H2020-MSCA-IF-2015 - - - 700838 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 195 454,80 - - - Spin triplet pairings in ferromagnet Josephson junctions - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - For a long time, the coexistence of conventional superconductivity and ferromagnetism was believed to be impossible. Cooper pairs in normal superconductors are formed by two electrons with antiparallel spins in a singlet - configuration while ferromagnets favour parallel alignment of electron spins. In 2001 it was theoretically predicted that under certain conditions both phases could coexist in hybrid structures, giving rise to a race for the discovery of an entirely - new kind of superconducting electron pairing state in which the electrons are in the triplet state. The novel hypothesis of this Action relies on the fact that triplet pairs can be formed combining ferromagnets, normal metals and superconductors into - hybrid Josephson junctions, and are stable enough to be used to carry spin information in addition to dissipationless charge transfer, which will represent an enormous improvement in comparison to the presently established spin-singlet-based devices. - - 2017-03-31, closed project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SPIN3 - - - H2020-MSCA-IF-2014 - - - 656485 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 195 454,80 - - - Cell-type Specific Mechanisms and Functional Consequences of Altered NMDA Receptor Development and Mecp2 Deficiency on Developing Cortical Circuits - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - NMDA receptor (NMDAR) dysfunction has been identified in multiple genetic causes of autism and related neurodevelopmental disorders. I recently showed that loss of Mecp2, the cause of Rett syndrome and some cases of autism, - differentially affects NMDAR development at cortical synapses on specific cell-types: slowing down the development in excitatory pyramidal neurons and accelerating the maturation in parvalbumin-positive (PV) inhibitory interneurons. Genetic - manipulation of NMDAR expression in Mecp2-deficient mice rescued both cortical function and the premature NMDAR maturation in PV cells. Based on these findings, I hypothesize that this cell-type specific disruption of NMDAR development leads to an - imbalance in excitation and inhibition in the developing cortical circuits. To test this idea, I will combine single cell genomic and cell-type specific recording techniques to elucidate how Mecp2 controls the development of synaptic receptors and - the impact on network function. In Aim 1, I will use cutting-edge techniques for single-cell RNA sequencing and synaptic recordings of NMDAR maturation in cortical cultures to identify novel cell-type specific mechanisms underlying NMDAR development - and the regulation by Mecp2. In Aim 2, I will investigate the functional effects of Mecp2 deficiency and altered NMDAR maturation on the development of cortical network activity using two-photon calcium imaging and multi-electrode array (MEA) - recordings. As a neuroscientist and neurologist, this training will prepare me for an independent research career addressing the circuit-based defects underlying Rett syndrome and autism. I have the full support of the University of Cambridge and - Wellcome Trust Sanger Institute for the proposed research and my career development. This study will improve our understanding of how loss of Mecp2 alters cortical circuits and has the potential to identify novel cell-type specific targets for - developing new therapies for Rett syndrome. - - 2018-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - NMDARETT - - - H2020-MSCA-IF-2015 - - - 700999 - - - - - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - - - EUR 150 000 - - - All Aqueous, continuous, Solid-Liquid SYNergisticEXTRACTion of rare earth elements - - - EUR 150 000 - - - France - France - - - Research Organisations - Research Organisations - - It is a matter of strategic independence for Europe to urgently find processes taking into account environmental and economic issues, when mining and recycling rare earth elements (REE). As of 2015, only 1% of used REE were - recycled in the EU and 80% of the mining operations were performed in China, hence representing a major Sword of Damoclès for the rest of the world’s economy. With SYNEXTRACT, we propose to leverage on discoveries made (and patented) within ERC-Adv - REE-CYCLE, related to new extracting liquid-liquid process. Hence, SYNEXTRACT will try to implement these discoveries in a Solid-liquid extraction process based on Simulated Moving Bed Chromatography. Such process would complement nicely the - liquid-liquid one. Indeed, in case of success, it would not only represent a new approach in chromatography, but it would also enable highly flexible purification processes for REEs containing waste streams, that can easily be adapted to various - waste stream lixiviates. Due to the high selectivity, it could even be applied to low REE concentration lixiviates. The process flexibility is one of the main bottleneck to enable their recycling as the research and development cost currently - necessary to adapt current liquid-liquid extraction processes prohibits it. It should also be mentioned that SYNEXTRACT process would be all aqueous, therefore avoid the use of organic solvent and would drastically reduce process wastes and running - costs. - - 2018-12-31, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - France - - - SYNEXTRACT - - - ERC-2017-PoC - - - 768722 - - - - - TEL AVIV UNIVERSITY - TEL AVIV UNIVERSITY - - - EUR 1 395 000 - - - The ‘Declining Significance of Gender’ Reexamined: Cross-Country Comparison of Individual and Structural Aspects of Gender Inequality - - - EUR 1 395 000 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The comparative research of long-term trends largely neglects structural mechanisms of gender inequality, i.e. the gender bias in which jobs and activities are evaluated and rewarded. I argue that as more women become - integrated in positions of power, the stronger the role of structural elements is likely to become. However, because these are less visible and amenable to empirical assessment, they are under-researched compared to individual aspects, and are - commonly assumed to be gender-neutral. The implication is that the importance of gender as a determinant of economic inequality in the labour market becomes insufficiently acknowledged, and thus difficult to track and eradicate. - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Israel - - - Struct. vs. Individ - - - ERC-2016-COG - - - 724351 - - - - - UNIVERSITEIT LEIDEN - - - EUR 177 598,80 - - - Voices of Belonging: Minority Identities, Language and Education in the Netherlands - - - EUR 177 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Youth radicalization is potential triggered by a sense of disconnect from society, and experiences of belonging carry important implications for youth identity formation. Language ideologies, policies, and practices in - educational contexts send messages for youth regarding their belonging and/or value in society: the voices heard by youth. In addition, youth communicate their sense of belonging and the belonging of others through their words and actions, including - their language choices and social affiliations: the voices of youth. The languages used and preferred by youth may or may not correlate with their educational achievement and identity positions. To illuminate the role of language and education in the - development of a sense of belonging by youth in culturally and linguistically diverse contexts, this study is based at a large multicultural school in The Hague and addresses, first, how youth experience, enact, and define a sense of belonging and/or - exclusion in their linguistic and educational contexts, second, how the language skills, language use choices, and linguistic affiliations of youth intersect with their educational achievements and sense of belonging, and third, the role of gender - and ethnicity in the intersecting influences of language, education, and identity for youth in ethnically and linguistically diverse contexts. These questions are addressed through three stages of research: initial observation as vital for contextual - depth and adaptation of appropriate questions, a questionnaire to quantitatively evaluate correlations among language, education, and identity, and a final in-depth stage providing student perspectives and supporting the interpretation of the - findings. A broader objective of this research is to inform policies and educational programs that serve ethnically and linguistically diverse youth, providing foundations for the development of more culturally responsive pedagogy in the Netherlands - and throughout Europe. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - Netherlands - - - Voices of Belonging - - - H2020-MSCA-IF-2016 - - - 752550 - - - - - FUNDACION CIRCE CENTRO DE INVESTIGACION DE RECURSOS Y CONSUMOS ENERGETICOS - TECHNISCHE UNIVERSITEIT EINDHOVEN - LABORATOIRE NATIONAL DE METROLOGIE ET D'ESSAIS - ENEL INGEGNERIA E RICERCA SPA - ENEL PRODUZIONE SPA - UNIVERSITY OF STRATHCLYDE - ORMAZABAL CORPORATE TECHNOLOGY, A.I.E. - FUNDACION PARA EL FOMENTO DE LA INNOVACION INDUSTRIAL - HAEFELY TEST AG - - - EUR 2 819 753,28 - - - Metrology Excellence Academic Network for Smart Grids - - - EUR 2 819 753,28 - - - Spain - Netherlands - France - Italy - Italy - United Kingdom - Spain - Spain - Switzerland - - - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - MEAN4SG network aims to educate 11 young researchers in the smart grids metrology field by constructing a training network gathering the whole innovation value chain. The main EU actors in the field of smart grids metrology - have worked together, under the umbrella of the European Association of National Metrology Institutes (EURAMET), and relying on the support of the International Electrotechnical Commission (IEC), in order to design a training program coping with the - principal R&D challenges related to metrology for smart grids while tackling the shortage of highly-skilled professionals on this area that has been foreseen by the European Commission, the electricity grids industrial sector and the academia. - - 2020-02-29, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Spain - - - MEAN4SG - - - H2020-MSCA-ITN-2015 - - - 676042 - - - - - ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE - ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE - - - EUR 1 998 393,75 - - - Inside the Self: from interoception to self- and other-awareness - - - EUR 1 998 393,75 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Modern psychology has long focused on the importance of the body as the basis of the self. However, this focus concerned the exteroceptive body, that is, the body as perceived from the outside, as when we recognize ourselves - in the mirror. This influential approach has neglected another important dimension of the body, namely the interoceptive body, that is, the body as perceived from within, as for example when one feels her racing heart. In psychology, research on - interoception has focused mainly on its role in emotion. INtheSELF, however, goes beyond this approach, aiming instead to show how interoception and interoceptive awareness serve the unity and stability of the self, analogous to the role of - interoception in maintaining physiological homeostasis. To test this hypothesis we go beyond the division between interoception and exteroception to consider their integration in self-awareness. INtheSELF will develop novel, pioneering methods for - the study of causal relationships between interoceptive and exteroceptive awareness (WP1), allowing us to test how these two sources of information about the self interact to reflect the balance between stability and adaptation (WP2); how their - inter-relation is built in parallel to the development of self-awareness in early childhood and adolescence (WP3); and the role that their interaction has for social relatedness (WP4). INtheSELF provides an alternative to existing psychological - theories of the self insofar it goes beyond the apparent antagonism between the awareness of the self from the outside and from within, to consider their dynamic integration. In doing so, INtheSELF aims to elucidate for the first time how humans - navigate the challenging balance between inside and out, in terms of both the individual’s natural (interoception vs. exteroception) and social (self vs. others) embodiment in the world. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - INtheSELF - - - ERC-2016-COG - - - 724537 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 150 000 - - - Multiple cellular screens using microfluidic droplets - - - EUR 150 000 - - - France - France - - - Research Organisations - Research Organisations - - Although some biotechnologies have made huge strides e.g. in automation, data generation, or biochemical methods, cell handling still uses antiquated methods that limit the scale at which assays can be performed. Our - ERC-funded microfluidics work has lead to cutting-edge microdroplet manipulation tools for cell handling: While working with 3D cell cultures, we have recently shown that we can obtain great increases in both throughput and detail, while reducing the - sample use and the machine footprint. In addition to these quantitative leaps, the microfluidic format also allows qualitatively new biological constructs to be explored by making significant steps towards the organ-on-a-chip framework. The current - project therefore aims to show how the technologies developed in our lab can function together in an integrated cell screening platform. This will require demonstrating a convincing proof of concept of the hardware, software, and workflow, in - addition to demonstrating the added value to different industries. - - 2018-12-31, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - France - - - Multiscreen - - - ERC-2017-PoC - - - 768790 - - - - - UNIVERSITE DE LIEGE - - - EUR 160 800 - - - Exploring the potential applications of live viral vaccine encoded small-hairpin-RNAs in improving both vaccine safety and efficacy through RNA-interference and stimulation of the innate immune system - - - EUR 160 800 - - - Belgium - - - Higher or Secondary Education Establishments - - Live vaccines represent one of the most important and effective interventions against the spread of viral disease. As such, they are instrumental in addressing ongoing societal challenges in areas such as healthcare and global - food security. However, their capacity to genetically recombine with wild type (WT) viruses circulating in the field remains a primary safety concern. Modifying live vaccine strains to reduce such occurrences would be highly desirable from a safety - perspective. Also efforts to enhance the intrinsic potency of vaccine strains would be very beneficial. This would facilitate the use of much lower doses, while reducing the manufacturing resources required to meet market needs and the cost of - vaccination programs. - - 2020-09-18, Grant Agreement signed - - - 2018-09-19 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - Belgium - - - Super-Vaccine - - - H2020-MSCA-IF-2016 - - - 753696 - - - - - BEN-GURION UNIVERSITY OF THE NEGEV - - - EUR 263 385 - - - Embodied and Abstract Concepts in Sensory-motor Deprivation - - - EUR 263 385 - - - Israel - - - Higher or Secondary Education Establishments - - How is information organized in the brain? Does our understanding of everyday concepts rely on our perceptual experience, and our ability to sense them? And can this uncover how abstract information is coded in our brains? - - 2018-04-30, ongoing project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Israel - - - EACISD - - - H2020-MSCA-IF-2014 - - - 654837 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 183 454,80 - - - Computational dynamics studies of drug metabolism by P450 enzymes - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Cytochrome P450 enzymes monitor the metabolism of many drugs and small-molecules, as well as selectively catalyze hydrocarbon substrates for application in biotechnology. Drug-drug interactions are critical to the management - of safe and effective pharmaceutical treatments. Thus, it is important to better understand the biological functions and activities of P450 enzymes not only to maximize their clinical significance but also to develop broader application in other - fields, such as biofuel. There has been significant investment in computational and theoretical studies of P450 enzymes; however, there remains a need for further dynamical calculations to better explore the involvement of the enzyme active site in - competing pathways leading to various products. This project aims to determine the role of P450 enzyme in alcohol and alkene formations, compare and contrast heme and non-heme Fe-containing active sites, and model the effect of enzyme environment, - using quantum mechanical calculations and inherent dynamics via quasi-classical simulation. The results from this study will help advance the field of computational modeling and its application in biologically important systems. - - 2019-06-20, ongoing project - - - 2017-06-21 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - metabolicomp - - - H2020-MSCA-IF-2016 - - - 752491 - - - - - DE MONTFORT UNIVERSITY - - - EUR 195 454,80 - - - Evolutionary Computation for Dynamic Constrained Optimization Problems - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Evolutionary computation (EC), as an efficient tool, has been widely applied to solve different kinds of stationary optimization problems. However, many real-world optimization problems are dynamic constrained optimization - problems (DCOPs), where the objective function, constraints, decision variables, and environmental parameters may change over time. At present, very few attempts have been made to investigate this kind of optimization problems in the communities of - optimization and EC. This project aims to fill this gap. In this project, we will concentrate on the design, analysis, and applications of EC for DCOPs, including the following five main aspects. Firstly, we will design a set of benchmark dynamic - constrained optimization test environments which can resemble real-world scenarios. Secondly, we intend to design standardized performance indicators to evaluate EC methods for DCOPs. Thirdly, based on the standardized dynamic test and evaluation - environments, we will design some novel and effective EC methods to solve DCOPs. Fourthly, we will present theoretical analysis of EC with different constraint-handling techniques for DCOPs, with the aim of establishing the theoretical foundation of - this area. Finally, applying the developed EC methods to deal with DCOPs in rail networks is also one key aspect of this project. This project has great potentials to fundamentally change the way in which DCOPs are treated, both from a real-world - point of view and from the point of view of advancing our theoretical understanding. The research results of this project will be of great interest to academia in many fields and of significant benefit to many industries that involve DCOPs. - - 2017-11-30, closed project - - - 2015-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ECDCOP - - - H2020-MSCA-IF-2014 - - - 661327 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 150 000 - - - Ultrasensitive Cartography of vectorial Force Fields at the nanoscale - - - EUR 150 000 - - - France - France - - - Research Organisations - Research Organisations - - This project aims at developing and disseminating a new class of ultrasensitive and vectorial force field sensors to build the next generation of scanning probes with improved sensitivity and vectorial readout capacity. The - vibrations of a singly clamped silicon carbide nanowire (NW) are readout by optical techniques. Its vibrating extremity oscillates in both transverse directions with quasi-degenerated frequencies due to its quasi-cylindrical geometry. When - approaching the NW above a sample surface it experiences an additional force field due to the sample-NW interaction which modifies its mechanical properties. The force field can be fully derived by monitoring frequency shifts and eigenmode rotations. - The measurement principle was demonstrated during the HQNOM ERC project by monitoring the perturbation of the NW Brownian motion, its random thermal noise in 2D induced by a voltage biased electrostatic tip. An impressive sensitivity to force field - gradients varying by less than 1e-18N over the nanometer sized Brownian motion was demonstrated, as well as a fully vectorial readout capacity which is unaccessible to existing 1D force probes. This vectorial sensitivity, combined with the - one-millon-fold improvement in force sensitivity over commercial atomic force microscopes is the starting point of the POC project. The objective is to ensure a wide dissemination of this extraordinary vectorial force field sensors and to progress - towards an industrial outreach of the apparatus. To do so, a demonstration prototype will be developed and will serve as a workhorse for the second step, the dissemination phase of the apparatus towards a broader scientific and industrial community. - - 2019-04-30, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - France - - - CARTOFF - - - ERC-2017-PoC - - - 767579 - - - - - KUNGLIGA TEKNISKA HOEGSKOLAN - KUNGLIGA TEKNISKA HOEGSKOLAN - - - EUR 1 499 180 - - - Microfiber Electrofluidics for Integrated Molecular Diagnostics - - - EUR 1 499 180 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - "Diagnosis of an increasing number of diseases (such as HIV, Ebola and antibiotic resistant bacteria) rely on centralized laboratories with specialized instruments and skilled personnel. This type of clinical analysis with - long lead times and high cost is inappropriate for point of care diagnostics. Portable, automated, and disposable devices with integrated molecular diagnostics (iMDx), could solve this problem. Such devices, however, basically do not exist today. - - - 2022-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Sweden - - - iMDx - - - ERC-2016-STG - - - 715268 - - - - - THE UNIVERSITY OF NOTTINGHAM - MATELYS - RESEARCH LAB - - - EUR 809 451,36 - - - European industrial doctorate for advanced, lightweight and silent, multifunctional composite structures - - - EUR 809 451,36 - - - United Kingdom - France - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Modern aeronautical structures are increasingly made of composite materials due to their well-known benefits. Despite their superior structural characteristics, composite structures exhibit poor dynamic and acoustic isolation - levels compared to conventional metallic ones. As a result and in order to maintain the comfort levels in the passenger and payload compartments within acceptable limits, additional acoustic and vibrational isolation technologies (sound packages) are - necessary in several transport applications. If non-optimally designed for a certain application, these sound packages can add substantial weight to the structure, compromising the weight benefits gained by the employment of composites. - - 2022-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-EID - European Industrial Doctorates - - - United Kingdom - - - N2N - - - H2020-MSCA-ITN-2017 - - - 765472 - - - - - KAROLINSKA INSTITUTET - - - EUR 173 857,20 - - - DNA Origami for drug delivery - - - EUR 173 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - The main objective of this project is to produce innovative DNA self-assembled nanostructures with the goal of evolving new approaches for drug delivery. The properties of the DNA nanostructures will be tuned by introducing - new elements into the nanostructures improving their versatility and structural integrity. This project will aim to: - - 2017-05-31, closed project | - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - VECTORIGAMI - - - H2020-MSCA-IF-2014 - - - 658676 - - - - - STICHTING CENTRUM VOOR WISKUNDE EN INFORMATICA - STICHTING CENTRUM VOOR WISKUNDE EN INFORMATICA - - - EUR 2 447 439 - - - Algebraic Methods for Stronger Crypto - - - EUR 2 447 439 - - - Netherlands - Netherlands - - - Research Organisations - Research Organisations - - Our field is cryptology. Our overarching objective is to advance significantly the frontiers in design and analysis of high-security cryptography for the future generation. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Netherlands - - - ALGSTRONGCRYPTO - - - ERC-2016-ADG - - - 740972 - - - - - FUNDACION BCMATERIALS - BASQUE CENTRE FOR MATERIALS, APPLICATIONS AND NANOSTRUCTURES - - - EUR 158 121,60 - - - Biological detection with functionalized Magnetic Sensor - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - The key goals of the BIDMAG project are: a) the training of a talented experienced researcher, Dr Lopes, in the fast growing field of science, technology and industrial applications of magnetic biosensors, where the host has a - critical knowledge and expertise; and, b) design, development and optimisation of cost-efficient smart hybrid surfaces onto magnetic substrates, able to present magnetic response for detecting bacteria. The interdisciplinary training program includes - magnetic materials surface modification, fabrication, modelling, characterisation of Magnetoelastic Resonators (MER), surface biofunctionalisation and detection of the biological parameters, which will enhance and broaden her expertise and increase - her exposure to both academic and industrial collaborations. She is a talented researcher who has gained much expertise in interdisciplinary area of electroactive polymer composites during her postgraduate career. This background is invaluable for - applying in preparation and characterisation techniques of smart materials. To further her career in magnetic biosensors Dr Lopes needs to gain expertise in functional materials and magnetic characterisation, fields in which BCMaterials has a - world-recognised expertise. Additionally, through secondments at academic and industrial co-hosts, at ACREO and VAC, respectively, she will gain additional training in: industrial production of MER and Optimization of compact and commercial MER - interrogation systems.The impact of the project will be multidisciplinary, since it has applications ranging from environmental monitorization and food quality control to fast medical diagnostics. Besides, to further boost her career, Dr Lopes needs - to increase her supervision and teaching experience, gain project and intellectual property management expertise, research funding and proposal writing skills. Multidisciplinary activities will assist her in acquiring necessary competences and - reaching professional maturity. - - 2018-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - BIDMAG - - - H2020-MSCA-IF-2015 - - - 701852 - - - - - THE UNIVERSITY OF NOTTINGHAM - THE UNIVERSITY OF NOTTINGHAM - - - EUR 149 932 - - - ImmortaSTEM: Transient Immortalisation for Patient Stem Cell Expansion and Therapeutic Application - - - EUR 149 932 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Under an ERC Advanced Grant, and subsequent PoC grant, Professor Shakesheff's team have invented a new intracellular delivery system that overcomes a problem in drug delivery in stem cell culture as well as regenerative - medicine and other therapeutic approaches. The system, called GAG-binding enhanced transduction (GET), enables intracellular delivery of proteins, nucleic acids and particles into cells that resist other non-viral strategies. The work under ERC - Advanced Grant and PoC funding has allowed exemplification of the delivery of proteins that promote pluripotency or differentiation, and delivery and expression of mRNA - - - 2018-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - ImmortaSTEM - - - ERC-2016-PoC - - - 754745 - - - - - KOBENHAVNS UNIVERSITET - - - EUR 212 194,80 - - - Characterizing drivers of intestinal tissue maturation in vitro and in vivo - - - EUR 212 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - One of the challenges in regenerative medicine is to generate adult intestinal stem cells (ISCs) from human induced pluripotent stem cells (hiPSC) in vitro in defined conditions. This will be important in order to establish - intestinal cell transplantation therapies and a platform for neonatal disease modelling. These issues constitute the main goal of the proposal. The current protocols to direct intestinal differentiation from hiPSC impede their suitability for human - transplantation purposes either because they require mice as tissue culture incubators (teratoma formation), long exposure to calf serum, or generate cells with fetal properties. The immature fetal intestine is distinct from its mature counterpart - most notably by its absence of differentiated secretory lineages. Moreover the precise location and developmental stage from which ISCs are specified in fetal intestine as well as the mechanisms that govern the progression towards an adult epithelium - remain to be elucidated. In order to generate adult ISCs from pluripotent sources it is instrumental to decipher the molecular mechanisms driving ISC maturation under physiological conditions. The project will be initiated with the fine mapping of - ISC origin in the fetal epithelium using cell tracing techniques. Then I will characterize how fetal ISCs acquire adult properties at the molecular level. In the host laboratory we hypothesize that differentially expressed transcription factors are - responsible for the unique characteristics of fetal and adult ISCs. Recently, using gene expression profiling comparing fetal and adult intestinal cells I have identified specific endodermal transcription factors overexpressed in the immature - structures. I expect through the modulation of such factors to trigger the intestinal maturation. To ensure the transferability of the results into clinics I will combine studies with murine models and cells from human fetal and adult intestines. - - 2018-01-31, closed project - - - 2016-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - fetISC - - - H2020-MSCA-IF-2014 - - - 656099 - - - - - CONSIGLIO NAZIONALE DELLE RICERCHE - CONSIGLIO NAZIONALE DELLE RICERCHE - UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA - FUNDACIO INSTITUT DE CIENCIES FOTONIQUES - - - EUR 2 381 875 - - - Composite integrated photonic platform by femtosecond laser micromachining - - - EUR 2 381 875 - - - Italy - Italy - Italy - Spain - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - - The quantum technology revolution promises a transformational impact on the society and economics worldwide. It will enable breakthrough advancements in such diverse fields as secure communications, computing, metrology, and - imaging. Quantum photonics, which recently received an incredible boost by the use of integrated optical circuits, is an excellent technological platform to enable such revolution, as it already plays a relevant role in many of the above - applications. However, some major technical roadblocks needs to be overcome. Currently, the various components required for a complete quantum photonic system are produced on very different materials by dedicated fabrication technologies, as no - single material is able to fulfil all the requirements for single-photon generation, manipulation, storage and detection. This project proposes a new hybrid approach for integrated quantum photonic systems based on femtosecond laser microfabrication - (FLM), enabling the innovative miniaturization of various components on different materials, but with a single tool and with very favourable integration capabilities. - - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Italy - - - CAPABLE - - - ERC-2016-ADG - - - 742745 - - - - - UNIVERSITY OF NEWCASTLE UPON TYNE - UNIVERSITY OF NEWCASTLE UPON TYNE - - - EUR 1 485 642,50 - - - Confidentiality-preserving Security Assurance - - - EUR 1 485 642,50 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - "This proposal aims to create a new generation of security assurance. It investigates whether one can certify an inter-connected dynamically changing system in such a way that one can prove its security properties without - disclosing sensitive information about the system's blueprint. - - - 2022-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - CASCAde - - - ERC-2016-STG - - - 716980 - - - - - HEINRICH-HEINE-UNIVERSITAET DUESSELDORF - - - EUR 171 460,80 - - - Development and characterization of an ultra-high performance mobile optical atomic clock based on lattice-trapped atoms - - - EUR 171 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - New types of atomic clocks, based on laser-cooled and trapped atoms interrogated by optical lasers, are changing the paradigm for precision measurement of time and frequency. Optical lattice clocks, which provide superb - frequency stability, are today complex systems, able to operate only in well-controlled laboratory environments and require continuous personnel intervention. The proposed activity aims to realize the transition from today's laboratory systems into - mature mobile instruments. The result of this transition opens outstanding and transformational future fields of application: world-wide accuracy comparisons of stationary clocks, high-precision tests of General Relativity, and mapping of the Earth - gravitational potential via relativistic geodesy. - - 2018-04-30, Grant Agreement terminated | - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Germany - - - Mobiclock - - - H2020-MSCA-IF-2015 - - - 707864 - - - - - ISTITUTO NAZIONALE DI FISICA NUCLEARE - - - EUR 180 277,20 - - - The anomalous magnetic moment of the muon as a benchmark for New Physics Searches - - - EUR 180 277,20 - - - Italy - - - Research Organisations - - The anomalous magnetic moment of the muon has revealed its potential to be the cornerstone for beyond the Standard Model searches, since it is one of the most accurately measured quantity in particle physics. Being the - Standard Model in a nutshell, is at the cutting edge of the developments in the field. A persistent discrepancy between theory and experiment exists and has triggered two new challenging and expensive experiments at FermiLab and at JPARC which will - push the measurement of that quantity to an unprecedented precision of a 0.14 ppm. At that level, differences beyond theoretical uncertainties among theory collaborations are limiting the theory precision. Thus, they must be resolved with an - exceptional precision as well to sort out whether the observed departure is and indication of New Physics and to correspond the enormous experimental effort. The project Gm2m aims to provide the theoretical framework to coordinate and elaborate on a - continuous and robust update of the Standard Model prediction of this observable through the use of 1) a user-friendly and modern web-page interface that should allow the community to keep track of the exact state-of-the-art calculation and 2) a new - reassessment with unparalleled precision of the uncertainties of the Standard Model. The project Gm2m will consider a set of novel approaches for finding a solution to the current theoretical puzzles, which also demands an exhaustive scrutiny of the - theoretical uncertainties at the 0.1ppm level. This effort should culminate in a most robust Standard Model prediction up to date. - - - 2019-06-30, Grant Agreement terminated - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - Gm2m - - - H2020-MSCA-IF-2015 - - - 702243 - - - - - UNIVERSIDAD DE ZARAGOZA - - - EUR 170 121,60 - - - Controlling Cell Fate through Smart Nanoheaters - - - EUR 170 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - Achieving the control of cellular processes is one of the most intriguing challenges in cell biology and medicine. Forefront approaches based on bioengineered nanoparticles might have the potential to target specific cell - pathways, thus controlling downstream cell activities in a space and time selective fashion. The present project aims to develop and to validate a smart nanovectorable to activate a specific cell signalling and, on demand, to induce heat mediated - cell death of nanovector targeted cells. As proof of concept, CONFINES is conceived to target the Wnt canonical pathway, one of the most studied and fascinating cell signalling, which orchestrates central mechanisms that govern cell proliferation, - polarity and stem cell fate. To achieve the proposed objectives, a controlled synthetic approach will tailor Wnt ligands on magnetic nanoparticles, combining targeting and magnetic properties in a uniquenanovector. Owing to its chemico-physical - features, NanoWnt will enable complete control of the cell signalling, and it will operate in vitro (human cell cultures) and in vivo (the aquatic invertebrateHydra vulgaris), in a dual mode: i) as an activator of the canonical Wnt pathway in those - contexts where it is inactive ii) or upon exposure to a magnetic field, as a nanoheater, enabling specific cell ablation by hyperthermia. From a technological point of view, the project will advance basic knowledge on thermal ablation (via magnetic - hyperthermia) and holds promises for translational medicine, providing a breakthrough tool to shape cell fate of nanovector receiving cells. Furthermore, combining diverse expertise, CONFINES will offer the applicant advanced and - multidisciplinarytraining in the field of nanomaterial synthesis, characterization and functionalisation as well as in hyperthermia technology, which will complement his current skills based on nanobiotechnology and cellular/molecular biology. - - 2017-09-08, Grant Agreement terminated | - - - 2015-09-09 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - CONFINES - - - H2020-MSCA-IF-2014 - - - 657566 - - - - - THE UNIVERSITY OF EDINBURGH - THE UNIVERSITY OF EDINBURGH - INTERACTIVE SCIENTIFIC LTD - - - EUR 149 951 - - - A Software Interface for Interactive Ensemble-Based Drug Design - - - EUR 149 951 - - - United Kingdom - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The ERC project EBDD was funded to bring about a new generation of computer algorithms to implement accurate molecular simulations of biomolecules and their interactions with man-made molecules that are potential new - therapeutics. First results from the EBDD project (ERC-StG-2013-336289) indicate the ground-breaking potential of the academic software generated for supporting pre-clinical drug discovery R&D in the pharmaceutical and biotech sectors. Building - on these early results from the EBDD project, this proposal aims to prototype an innovative interactive human-computer drug design workflow that will enhance the value of the academic software, and enable new types of R&D processes (hit - discovery, hit-to-lead and lead-optimisation) in a preclinical drug discovery environment. - - - 2018-12-31, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - iEBDD - - - ERC-2016-PoC - - - 754654 - - - - - UNIVERZITA PAVLA JOZEFA SAFARIKA V KOSICIACH - OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN - THE TRUSTEES OF BOSTON UNIVERSITY - THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - THE GENERAL HOSPITAL CORPORATION - OREGON HEALTH AND SCIENCE UNIVERSITY - - - EUR 351 000 - - - Adaptation, learning and training for spatial hearing in complex environments - - - EUR 441 000 - - - Slovakia - Austria - United States - United States - United States - United States - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - - In everyday situations, humans are exposed to multiple concurrent stimuli in complex, continuously changing environments. To correctly extract relevant information, they adapt their processing to reflect the specifics of the - current scene, and they learn from previous experience to improve the perceptual strategies used. The current project proposes to perform a series of behavioral experiments, brain imaging studies, and computational modeling 1) to study the auditory - mechanisms of adaptation to new reverberant environments for speech processing, sound localization, and learning of new phonetic categories, and 2) to study how attention and mechanisms of implicit and explicit learning are used to cope with complex - listening environments. The results will be important, e.g., for development of new prosthetic devices and new virtual reality technologies. Here, they will be used to develop a brain training game that can improve impaired listeners’ performance in - complex environments. An additional goal of the proposal is to obtain new knowledge and skills related to studying human perceptual processes and the corresponding neural mechanisms. Skills to perform sensory learning research, psychophysics, - non-invasive brain imaging (EEG and fMRI), and computational modeling will be exchanged during the secondments. Also, a series of workshops will be organized to train new researchers to perform research in computational and cognitive neuroscience, - with additional goal of enhancing the exchange of information among participants and sharing new results obtained in this project. The project consortium consists of academic, research, medical, and small enterprise organizations based in the EU and - USA. The participants have complementary skills necessary to achieve all the defined goals. Their collaboration on this project will result in strengthening of the European Research Area and in establishing new long-term collaborations between EU and - US researchers. - - 2018-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Slovakia - - - ALT - - - H2020-MSCA-RISE-2015 - - - 691229 - - - - - UNIVERSIDAD DE GRANADA - ISTITUTO NAZIONALE DI GEOFISICA E VULCANOLOGIA - ILMATIETEEN LAITOS - EISCAT SCIENTIFIC ASSOCIATION - UNIVERSITAET BREMEN - HELSINGIN YLIOPISTO - MARINE INSTITUTE - UNIVERSITA DEGLI STUDI DELLA TUSCIA - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - - - EUR 1 997 990 - - - COOPERATION OF RESEARCH INFRASTRUCTURES TO ADDRESS GLOBAL CHALLENGES IN THE ENVIRONMENT FIELD - - - EUR 1 997 990 - - - Spain - Italy - Finland - Sweden - Germany - Finland - Ireland - Italy - France - - - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - - The COOP+ project is motivated by the interest of several Research Infrastructures in Europe to benefit from extending international collaboration with other Research Infrastructures in their areas of expertise at global, worldwide level. - - 2018-08-31, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.3.2."> - - - INFRASUPP-6-2014 - International cooperation for research infrastructures - - - CSA - Coordination and support action - - - Spain - - - COOP_PLUS - - - H2020-INFRASUPP-2014-2 - - - 654131 - - - - - ISTITUTO NAZIONALE DI FISICA NUCLEARE - STIFTUNG DEUTSCHES ELEKTRONEN-SYNCHROTRON DESY - OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN - THE HENRYK NIEWODNICZANSKI INSTITUTE OF NUCLEAR PHYSICS, POLISH ACADEMY OF SCIENCES - UNIVERZITA KARLOVA - INSTITUT JOZEF STEFAN - MIDDLE EAST TECHNICAL UNIVERSITY - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - INSTITUTO DE FISICA DE ALTAS ENERGIAS - NARODOWE CENTRUM BADAN JADROWYCH - QUEEN MARY UNIVERSITY OF LONDON - SCIENCE AND TECHNOLOGY FACILITIES COUNCIL - COSTRUZIONI APPARECCHIATURE ELETTRONICHE NUCLEARI C.A.E.N. SPA - INTER-UNIVERSITY RESEARCH INSTITUTE CORPORATION, HIGH ENERGY ACCELERATOR RESEARCH ORGANISATION - NATIONAL UNIVERSITY CORPORATION THEUNIVERSITY OF TOKYO - - - EUR 2 308 500 - - - Japan and Europe Network for Neutrino and Intensity Frontier Experimental Research - - - EUR 2 308 500 - - - Italy - Germany - Austria - Poland - Czech Republic - Slovenia - Turkey - France - France - Spain - Poland - United Kingdom - United Kingdom - Italy - Japan - Japan - - - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - European particle physics groups interested in searching signals of new physics both with neutrinos, at T2K experiment, and at the intensity frontier, with the Belle-II experiment at the SUPERKEKB machine, want to share - between them and with KEK laboratory their knowledge in data analysis and detector technologies. Such knowledge sharing will enhance skills and competences of all participants, will allow Europe to play a primary role in the search for deviations - from the actually known fundamental physics in the flavour sector and, last but not least, will produce an unprecedented collaboration with japanese scientists on the ground of dissemination and outreach. - - 2019-03-31, ongoing project | - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Italy - - - JENNIFER - - - H2020-MSCA-RISE-2014 - - - 644294 - - - - - UNIVERSIDAD POLITECNICA DE MADRID - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - OFFICE NATIONAL D'ETUDES ET DE RECHERCHES AEROSPATIALES - DEUTSCHES ZENTRUM FUER LUFT - UND RAUMFAHRT EV - INSTITUT VON KARMAN DE DYNAMIQUE DES FLUIDES - NUMERICAL MECHANICS APPLICATIONS INTERNATIONAL SA - AIRBUSGROUP LIMITED - KATHOLIEKE UNIVERSITEIT LEUVEN - KUNGLIGA TEKNISKA HOEGSKOLAN - - - EUR 3 900 365,28 - - - Stability and Sensitivity Methods for Industrial Design - - - EUR 3 900 365,28 - - - Spain - United Kingdom - United Kingdom - France - Germany - Belgium - Belgium - United Kingdom - Belgium - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The increasing environmental awareness of the European society has been always present in the aeronautical community, industry and research centres, having a definite influence on the way the aircraft of the future should be. - In this line, the ACARE Vision for 2020, a Group of Renowned Personalities in the aeronautical field, has formulated a clear set of requirements for civil transport aircraft operations in order to reach the following specific environmental goals: - halving perceived aircraft noise, 50% cut in CO2 emissions per passenger-km and 80% cut in NOx emissions. - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Spain - - - SSeMID - - - H2020-MSCA-ITN-2015 - - - 675008 - - - - - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - KAROLINSKA INSTITUTET - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSITE DE LIEGE - UCB PHARMA SA - ASTRAZENECA AB - SANOFI-AVENTIS DEUTSCHLAND GMBH - - - EUR 3 948 843,96 - - - ISOTOPIC LABELING FOR DRUG INNOVATION - - - EUR 3 948 843,96 - - - France - United Kingdom - Sweden - France - Belgium - Belgium - Sweden - Germany - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Excessive attrition rates during clinical trials dramatically impact on Drug Discovery and Development (DDD). Absorption, Distribution, Metabolism and Excretion studies carried out on larger series of drug candidates at an - earlier stage of the DDD timeline and evaluation of drug efficacy through better assessment of pharmacokinetic/pharmacodynamic relationships, target engagement and receptor occupancy are critically important approaches for de-risking drug innovation - since they facilitate early identification of the candidates that display the best in vivo profile. When successfully implemented, this strategy can accelerate the discovery of new therapeutic solutions to existing and emerging diseases, and enhance - European pharmaceutical innovation. For implementation, large sets of isotopically-labeled molecules are required and consequently, a huge revival of labeling techniques is urgently needed. Another crucial issue is the scarcity of expert - radiochemists in Europe and the lack of first class training programs in this inter-disciplinary field merging chemistry, radiochemistry and medicinal chemistry. The aims of ISOTOPICS are: i) to train the next generation of European chemists with - expertise in isotopic labeling and advanced medicinal chemistry through a first-class taught and research training program combined with a highly interactive secondments plan; ii) to develop innovative and general isotopic labeling chemistry and - radiochemistry to streamline the synthesis of labeled small-molecule drugs and biologics; iii) to work closely with the European pharmaceutical industry to apply the new labeling methods to drugs currently in development in order to provide solutions - to the most pressing problems in drug innovation. This highly interdisciplinary project is expected to have a profound beneficial impact on drug innovation in Europe by providing novel efficient techniques and new experts in the fields of labeling - and medicinal chemistries. - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - France - - - ISOTOPICS - - - H2020-MSCA-ITN-2015 - - - 675071 - - - - - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - ARISTOTELIO PANEPISTIMIO THESSALONIKIS - INSILICO BIOTECHNOLOGY AG - PROCESS SYSTEMS ENTERPRISE LIMITED - SILICOLIFE LDA - HUMBOLDT-UNIVERSITAET ZU BERLIN - PROTATOUANS - ETAIREIA EREYNAS VIOTECHNOLOGIAS MONOPROSOPI ETAIREIA PERIORISMENIS EYTHINIS - RIJKSUNIVERSITEIT GRONINGEN - UNIVERSITAETSKLINIKUM AACHEN - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - - - EUR 3 805 423,20 - - - Systematic Models for Biological Systems Engineering Training Network - - - EUR 3 805 423,20 - - - United Kingdom - Spain - Greece - Germany - United Kingdom - Portugal - Germany - Greece - Netherlands - Germany - Switzerland - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Mathematical, computational models are central in biomedical and biological systems engineering; models enable (i) mechanistically justifying experimental results via current knowledge and (ii) generating new testable - hypotheses or novel intervention methods. - - - 2019-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - SyMBioSys - - - H2020-MSCA-ITN-2015 - - - 675585 - - - - - UNIVERSITE D'AIX MARSEILLE - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - UNIVERSITE CATHOLIQUE DE LOUVAIN - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSITAIR MEDISCH CENTRUM UTRECHT - AALTO-KORKEAKOULUSAATIO - SAINT PETERSBURG NATIONAL RESEARCH UNIVERSITY OF INFORMATION TECHNOLOGIES, MECHANICS AND OPTICS - THE AUSTRALIAN NATIONAL UNIVERSITY - MULTIWAVE TECHNOLOGIES AG - MR COILS BV - - - EUR 3 945 346,25 - - - MetaMaterials antenna for ultra-high field MRI - - - EUR 4 582 346,25 - - - France - France - Belgium - France - Netherlands - Finland - Russia - Australia - Switzerland - Netherlands - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - M-Cube aims at changing the paradigm of High-Field MRI and Ultra High-Field antennas to offer a much better insight on the human body and enable earlier detection of diseases. Our main objective is to go beyond the limits of - MRI clinical imaging and radically improve spatial and temporal resolutions. The clinical use of High-field MRI scanners is drastically limited due to the lack of homogeneity and to the Specific Absorption Rate (SAR) of the Radio Frequency (RF) - fields associated with the magnetic resonance. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-01-2016-2017 - FET-Open research and innovation actions - - - RIA - Research and Innovation action - - - France - - - M-CUBE - - - H2020-FETOPEN-1-2016-2017 - - - 736937 - - - - - UNIVERSITE PARIS XII VAL DE MARNE - THE UNIVERSITY OF LIVERPOOL - FUNDACION DE INVESTIGACION DEL CANCER DE LA UNIVERSIDAD DE SALAMANCA - STICHTING KATHOLIEKE UNIVERSITEIT - INSTYTUT BIOLOGII DOSWIADCZALNEJ IM. M. NENCKIEGO POLSKIEJ AKADEMII NAUK - ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS - UNIVERSITAT AUTONOMA DE BARCELONA - SCREENCELL - - - EUR 3 991 096,25 - - - 3-O-sulfated heparan sulfate translocation in altered membrane biology: A newstrategy for early population screening and halting Alzheimer’s neurodegeneration - - - EUR 3 991 096,25 - - - France - United Kingdom - Spain - Netherlands - Poland - France - Spain - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - ArrestAD proposes a novel and visionary thinking resulting from the demonstration of the central role of a particular heparan sulfate species at the intracellular level in neurons and in circulating cells in the molecular - pathology of Alzheimer’s disease (AD). AD is a societal challenge for which there is neither prevention nor possible cure. Research in the field has long been refining classic concepts based on the aggregation of Aβ and tau through initial seeding - and then spreading. Our vision is different and based on the demonstration that tau abnormal phosphorylation and aggregation is triggered by the interaction of tau with heparan sulfates internalized in neurons and circulating cells only in AD [UPEC - R.1; P.1,2]. Based in this new concept, ArrestAD will establish links between AD genetics, disease hallmarks, and altered traffic and intracellular accumulation of heparan sulfates to generate new knowledge underpinning the development of new - strategies for detection and treatment of AD. This will open to radically new technologies addressing two major objectives: 1) proving that specific and early diagnosis of AD is possible in circulating cells, and 2) demonstrating that a new class of - drug candidates are able to preventing and/or arresting AD-neurodegeneration. To reach these objectives, ArrestAD brings together internationally recognized experts in AD clinics and diagnosis, in heparan sulfate biology, transcriptomics, - interactomics, carbohydrate chemistry, enzymology, cell biology, animal experimentation with AD models, and a SME specialized in the development of diagnosis kits using circulating cells. The high-risk character of this joint science and technology - research is offset by the multidisciplinary nature of the Consortium and the high socio-economic gain resulting from success. Based in this technology, we will build a diverse portfolio of future projects that will result in a long-term benefit for - citizens, economy and society. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-01-2016-2017 - FET-Open research and innovation actions - - - RIA - Research and Innovation action - - - France - - - ArrestAD - - - H2020-FETOPEN-1-2016-2017 - - - 737390 - - - - - STIFTUNG DEUTSCHES ELEKTRONEN-SYNCHROTRON DESY - FORSCHUNGSZENTRUM JULICH GMBH - B.P. KONSTANTINOV PETERSBURG NUCLEAR PHYSICS INSTITUTE - RUSSIAN RESEARCH CENTRE KURCHATOV INSTITUTE - FACILITY FOR ANTIPROTON AND ION RESEARCH IN EUROPE GMBH - JOINT INSTITUTE FOR NUCLEAR RESEARCH - HELMHOLTZ-ZENTRUM GEESTHACHT ZENTRUM FUR MATERIAL- UND KUSTENFORSCHUNG GMBH - TECHNISCHE UNIVERSITAET MUENCHEN - INSTITUT MAX VON LAUE - PAUL LANGEVIN - EUROPEAN SPALLATION SOURCE ERIC - EUROPEAN SPALLATION SOURCE ESS AB - INSTALLATION EUROPEENNE DE RAYONNEMENT SYNCHROTRON - EUROPEAN X-RAY FREE-ELECTRON LASERFACILITY GMBH - ASSOCIATION INTERNATIONALE EXTREME-LIGHT-INFRASTRUCTURE DELIVERY CONSORTIUM - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - INSTITUTE OF APPLIED PHYSICS, RUSSIAN ACADEMY OF SCIENCES - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH - Budker Institute of Nuclear Physics of SB RUS - FEDERAL SCIENTIFIC RESEARCH CENTRECRYSTALLOGRAPHY AND PHOTONICS OF THE RUSSIAN ACADEMY OF SCIENCES - LUNDS UNIVERSITET - - - EUR 1 696 250 - - - Connecting Russian and European Measures for Large-scale Research Infrastructures - - - EUR 1 696 250 - - - Germany - Germany - Russia - Russia - Germany - Russia - Germany - Germany - France - Sweden - Sweden - France - Germany - Belgium - France - Russia - Switzerland - Russia - Russia - Sweden - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Research Organisations - Other - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - - This CREMLIN proposal is to foster scientific cooperation between the Russian Federation and the European Union in the development and scientific exploitation of large-scale research infrastructures. It has been triggered by - the recent so-called megascience projects initiative launched by and in the Russian Federation which is now very actively seeking European integration. The proposed megascience facilities have an enormous potential for the international scientific - communities and represent a unique opportunity for the EU to engage in a strong collaborative framework with the Russian Federation. - - 2018-08-31, ongoing project | - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.3.2."> - - - INFRASUPP-6-2014 - International cooperation for research infrastructures - - - CSA - Coordination and support action - - - Germany - - - CREMLIN - - - H2020-INFRASUPP-2014-2 - - - 654166 - - - - - UNIVERSITA DEGLI STUDI DI MACERATA - PHILIPS ELECTRONICS NEDERLAND B.V. - KATHOLIEKE UNIVERSITEIT LEUVEN - - - EUR 1 527 991,20 - - - HEalth related Activity Recognition system based on IoT – an interdisciplinary training program for young researchers - - - EUR 1 527 991,20 - - - Italy - Netherlands - Belgium - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - A current trend in healthcare involves the prevention of chronic diseases by changing behaviour towards more healthy lifestyle choices. This is supported by the increased use of wearable sensors and Internet of Things (IoT) - devices. Human activity recognition and vital sign monitoring play a significant role in tailoring personal health and behaviour change coaching solutions to each individual, but pose a number of technical, legal, and socio-economic issues, which - must be solved to enable a commercial viable solution. - - 2021-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2017 - Innovative Training Networks - - - MSCA-ITN-EID - European Industrial Doctorates - - - Italy - - - HEART - - - H2020-MSCA-ITN-2017 - - - 766139 - - - - - THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS - THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS - - - EUR 1 498 052 - - - The Ethics of Oil: Finance Moralities and Environmental Politics in the Global Oil Economy - - - EUR 1 498 052 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In October 2014, the Chairman of the Bank of England Mark Carney warned that many oil reserves cannot be developed. If so, they would contribute so significantly to increased greenhouse gas emissions that international targets - to avoid dangerous levels of global warming would be exceeded. However, stock valuations of oil companies assume that all proven and probable reserves can indeed be produced. Amounting to a potentially enormous debt overhang, the Bank of England has - launched an enquiry into the threat of a crisis similar to the subprime mortgage crash, known as the ‘carbon bubble’. This looming crisis with its ‘stranded assets’ raises urgent questions about the conflicting dynamics between finance moralities and - environmental politics at a time of oil dependency and an uncertain climate future. Grounded in ethnographic fieldwork with oil companies in the US and Norway, energy analysts in the UK and the US, and fossil fuel divestment movements in Germany and - the UK, ENERGY ETHICS will develop a new framework for understanding the relationship between oil, money and climate change that counters the prevalent tendency to interpret these issues through aggregated normative systemic analysis only. Taking its - starting point in people’s own perceptions of and direct involvement in the oil economy, it will offer a major step forward in understanding how people in positions of influence within the oil economy make financial and ethical valuations of oil. - This will contribute to public stakeholder dialogue and wider transdisciplinary engagements. Focusing on oil and its financialization, ENERGY ETHICS has three main research objectives: 1) to examine how people positioned strategically in relation to - the global production of oil conceptualise and influence the oil market; 2) to understand the linkages and frictions between these different valuations of oil; and 3) to investigate how oil valuations relate to political reforms and new climate - economic initiatives. - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - ENERGY ETHICS - - - ERC-2016-STG - - - 715146 - - - - - ISTITUTO NAZIONALE DI FISICA NUCLEARE - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - STIFTUNG DEUTSCHES ELEKTRONEN-SYNCHROTRON DESY - UNIVERSITAT POLITECNICA DE VALENCIA - ATOS SPAIN SA - CONSORZIO INTERUNIVERSITARIO RISONANZE MAGNETICHE DI METALLO PROTEINE - ISTITUTO NAZIONALE DI ASTROFISICA - LABORATORIO DE INSTRUMENTACAO E FISICA EXPERIMENTAL DE PARTICULAS - KARLSRUHER INSTITUT FUER TECHNOLOGIE - UNIVERSITEIT UTRECHT - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH - T-SYSTEMS INTERNATIONAL GMBH - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - FONDAZIONE CENTRO EURO-MEDITERRANEO SUI CAMBIAMENTI CLIMATICI - Istituto Centrale per il Catalogo Unico delle biblioteche italiane e per le informazioni bibliografiche - SANTER REPLY SPA - AKADEMIA GORNICZO-HUTNICZA IM. STANISLAWA STASZICA W KRAKOWIE - INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK - STICHTING EGI - INDRA SISTEMAS SA - CONSIGLIO NAZIONALE DELLE RICERCHE - SCIENCE AND TECHNOLOGY FACILITIES COUNCIL - CESNET ZAJMOVE SDRUZENI PRAVNICKYCH OSOB - ISTITUTO NAZIONALE DI GEOFISICA E VULCANOLOGIA - RUDER BOSKOVIC INSTITUTE - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - - - EUR 11 138 114 - - - INtegrating Distributed data Infrastructures for Global ExplOitation - - - EUR 11 565 239 - - - Italy - Spain - Germany - Spain - Spain - Italy - Italy - Portugal - Germany - Netherlands - Switzerland - Germany - France - Italy - Italy - Italy - Poland - Poland - Netherlands - Spain - Italy - United Kingdom - Czech Republic - Italy - Croatia - France - - - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - - The INDIGO-DataCloud project (INDIGO for short) aims at developing a data/computing platform targeted at scientific communities, deployable on multiple hardware, and provisioned over hybrid (private or public) - e-infrastructures. This platform will be built by leading European developers, resource providers, e-infrastructures and scientific communities in order to ensure its successful exploitation and sustainability. - - 2017-09-30, closed project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.3."> - - - EINFRA-1-2014 - Managing, preserving and computing with big research data - - - RIA - Research and Innovation action - - - Italy - - - INDIGO-DataCloud - - - H2020-EINFRA-2014-2 - - - 653549 - - - - - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - CENTRO DE INVESTIGACIONES ENERGETICAS, MEDIOAMBIENTALES Y TECNOLOGICAS-CIEMAT - NARODOWE CENTRUM BADAN JADROWYCH - - - EUR 4 653 523,88 - - - QUAdrupoleCOrrector - - - EUR 6 647 891,25 - - - Switzerland - France - Spain - Poland - - - Research Organisations - Research Organisations - Research Organisations - Research Organisations - - The full exploitation of the Large Hadron Collider (LHC) is the highest priority of the European Strategy for particle physics. Because of this accelerator Europe is in a leading global position on High Energy Physics - research. To preserve that position, the LHC will need a major upgrade in the 2020s to increase its luminosity by a factor of five beyond its design value. The novel configuration, known as High Luminosity LHC, is based on the development of key - innovative technologies representing exceptional technological challenges. - - 2020-02-29, ongoing project | - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.2.1."> - - - INFRASUPP-2-2015 - Innovative procurement pilot action in the field of scientific instrumentation - - - COFUND-PCP - COFUND (PCP) - - - Switzerland - - - Quaco - - - H2020-INFRASUPP-2015-2 - - - 689359 - - - - - FUNDACIO INSTITUT DE CIENCIES FOTONIQUES - - - EUR 170 121,60 - - - Visualising Chromatin Structure and Dynamics at the Nanometre Scale with Super-Resolution Fluorescence Microscopy - - - EUR 170 121,60 - - - Spain - - - Research Organisations - - Recently, it has become evident that the spatial organization of chromatin within nuclei is a key factor that can regulate gene silencing and expression. This organization is particularly important in pluripotent stem cells - that differentiate into all cell types of the body through chromatin remodelling coupled to altered gene expression. Therapeutic use of these cells demands precise control over chromatin structure to direct differentiation. However, chromatin - structure remains poorly resolved due to the nanometre length scales involved and limitations of low spatial resolution, poor signal-to-noise and ensemble averaging in existing methods. VCSD utilizes cutting-edge super-resolution fluorescence - microscopy (SRFM) that overcomes these limitations. VCSD will, for the first time: 1) visualize global, 3D chromatin nanoscale structure in individual cells during differentiation; and 2) correlate the dynamics of local chromatin restructuring with - the silencing of a central pluripotency gene. The proposed Marie Curie Fellow, Jason Otterstrom, PhD Harvard Biophysics, has extensive experience in fluorescence microscopy applied to biological systems. The host lab supervisor, Dr. Loza-Alvarez, is - an expert in SRFM, at the Institute for Photonic Sciences, Barcelona. A secondment is planned in the lab of Dr. Cosma, an expert in the genetic mechanisms controlling pluripotency, at the Barcelona Center for Genomic Regulation. The combined - expertise of the fellow and host labs is uniquely suited to establish VCSD as a novel framework for characterizing chromatin structure. The methodology developed is anticipated to be adopted by researchers in stem cell and chromatin biology fields, - thereby reinforcing Europe’s global reputation in scientific innovation. The Fellowship will enable Jason to pursue applications of the chromatin structural metrics determined here as an independent biophysical researcher, with the long-term goal of - commercializing a stem cell classification system. - - 2018-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - VCSD - - - H2020-MSCA-IF-2014 - - - 656873 - - - - - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - - - EUR 173 076 - - - HIV/SIV exploits DCs in mucosal infection: mechanisms of transmission and modulation by semen associated factors - - - EUR 173 076 - - - France - - - Research Organisations - - Worldwide a large proportion of all new cases of HIV-1 infection are due to anal sexual intercourse, being the anal/rectal as well as distal colonic mucosa a site of viral uptake and entry. I recently demonstrated that - intestinal lamina propria resident DCs migrate towards and extend cellular processes between the tight junctions of columnar epithelium through a CCR5-dependent mechanism, take up R5 but not X4 HIV-1, and then transfer infection to susceptible T - cells. Although in mice CX3CR1+DCs are deputed to shuttle microbial antigens, there is no clear idea on which subsets of DCs are located in the human GI tract, are involved in HIV infection and contribute to virus spread, its presentation or possibly - to its reservoir. Moreover, the ability of DCs to shuttle the virus across the mucosa may be largely modulated by components of semen, the natural vehicle of HIV during sexual transmission. - - 2017-06-30, closed project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - DCmucoHIV - - - H2020-MSCA-IF-2014 - - - 658277 - - - - - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - - - EUR 185 076 - - - Investigation of shape evolution in neutron-rich nuclei using gamma-ray spectroscopy techniques - - - EUR 185 076 - - - France - - - Research Organisations - - In the past 100 years, various theoretical approaches have been proposed to model the complex strong interaction between the neutrons and protons in a nucleus, however, a thorough understanding of its quantum structure is - still far from being complete. Studies of the evolution of nuclear structure in mass regions away from the valley of stability have revealed dramatic modifications of the ordering of single-particle orbitals in exotic nuclei as compared to the ones - predicted by the Shell Model. These surprising results have prompted the need for a detailed study of exotic nuclear systems in order to identify the driving forces behind them. The experimental study of these highly unstable exotic nuclear systems - is extremely challenging and have become possible only recently due to the advent of radioactive ion beam facilities and highly efficient detection systems. - - 2018-10-02, ongoing project - - - 2016-10-03 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - Shape Evolution - - - H2020-MSCA-IF-2015 - - - 702590 - - - - - HELSINGIN YLIOPISTO - - - EUR 179 325,60 - - - The developmental and evolutionary basis of human intersubjectivity - - - EUR 179 325,60 - - - Finland - - - Higher or Secondary Education Establishments - - This research aims to unravel the ontogenetic and phylogenetic roots of the unique human intersubjectivity. Empathy forms the basis of intersubjectivity. In the first part of the research, we address empathy development in - young, 6-16-month-old infants who engage in interactive, intentional communication but do not yet cognitively represent others’ mental states. They may, however, attend to and show concern of others’ emotional states, indicating dispositional - empathic orientation. This tendency is tested in a peer context, involving emotions of positive and negative valence. In addition, we assess the infants’ early communicative and prosocial behaviours in the emotionally charged situation. This will - reveal the early developmental phases of the fundamental base for intersubjectivity. In the second part of the research, the evolution intersubjectivity is tested by assessing empathy in non-human primates. According to the recent cooperative - breeding hypothesis, humans evolved as cooperative breeders, which increased sensitivity and motivation to attend to and show concern of others’ emotional states. The hypothesis is tested by assessing rudimentary empathy in common marmosets, a - distantly related cooperatively breeding monkey. To allow full comparability, we will use identical methods in the infant and the marmoset studies. The study incorporates theoretical backgrounds and methods from several disciplines, i.e., comparative - cognition, animal behaviour, developmental psychology, evolutionary anthropology, and sociological interaction research. The multidisciplinary approach yields understanding of the emotional and cognitive foundation of intersubjective interactions no - single discipline can achieve alone. Moreover, the study yields fruitful prospects for future research lines in the respective disciplines and their synthesis. - - 2017-09-30, closed project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Finland - - - DEVOLEMPA - - - H2020-MSCA-IF-2014 - - - 653957 - - - - - OFFICE NATIONAL D'ETUDES ET DE RECHERCHES AEROSPATIALES - OFFICE NATIONAL D'ETUDES ET DE RECHERCHES AEROSPATIALES - - - EUR 1 377 290 - - - AEROelastic instabilities and control of FLEXible Structures - - - EUR 1 377 290 - - - France - France - - - Research Organisations - Research Organisations - - Aeroelastic instabilities are at the origin of large deformations of structures and are limiting the capacities of products in various industrial branches such as aeronautics, marine industry, or wind electricity production. - If suppressing aeroelastic instabilities is an ultimate goal, a paradigm shift in the technological development is to take advantage of these instabilities to achieve others objectives, as reducing the drag of these flexible structures. The - ground-breaking challenges addressed in this project are to design fundamentally new theoretical methodologies for (i) describing mathematically aeroelastic instabilities, (ii) suppressing them and (iii) using them to reduce mean drag of structures - at a low energetic cost. To that aim, two types of aeroelastic phenomena will be specifically studied: the flutter, which arises as a result of an unstable coupling instability between two stable dynamics, that of the structures and that the flow, - and vortex-induced vibrations which appear when the fluid dynamics is unstable. An aeroelastic global stability analysis will be first developed and applied to problems of increasing complexity, starting from two-dimensional free-vibrating rigid - structures and progressing towards three-dimensional free-deforming elastic structures. The control of these aeroelastic instabilities will be then addressed with two different objectives: their suppression or their use for flow control. A - theoretical passive control methodology will be established for suppressing linear aeroelastic instabilities, and extended to high Reynolds number flows and experimental configurations. New perturbation methods for solving strongly nonlinear problems - and adjoint-based control algorithm will allow to use these aeroelastic instabilities for drag reduction. This project will allow innovative control solutions to emerge, not only in flutter or vortex-induced vibrations problems, but also in a much - broader class of fluid-structure problems. - - 2020-06-30, ongoing project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - AEROFLEX - - - ERC-2014-STG - - - 638307 - - - - - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - - - EUR 173 076 - - - Broadband Superconducting Nanowire Single Photon Detectors - - - EUR 173 076 - - - France - - - Research Organisations - - Single-photon detection is an emerging technology, with applications ranging from medical imaging and LIDAR systems to space communication and fundamental quantum optics. Moreover, single-photon detectors are considered an - enabling technology for the development of quantum information science, paving the way for the realization of one of the main challenges of the 21st century: the quantum computer. Currently, single-photon detection is carried out using - semiconductor-based avalanche photodiodes; however, this technology is limited by large timing jitter, unavoidable dark counts, after pulsing, and limited detection efficiency. A recently proposed alternative relies on a superconducting nanowire - biased just below its critical current, so that an impinging photon triggers a transition from the superconducting to the normal state, resulting in a voltage spike at the nanowire leads. The detection efficiency can be boosted close to unity by - coupling the superconducting nanowire to the evanescent field propagating in a waveguide. However, the fabrication of high quality, ultra-thin superconducting layers is challenging, and the operation wavelength of such devices is limited by the - waveguide band gap. We have identified GaN/AlN as the best suited waveguide material system, approximately lattice matched with NbN, and with a transparent band from 400 to 6000 nm. The target of the SuSiPOD project is the establishment of a - technology platform for the fabrication of a new generation of broadband superconducting nanowire single-photon detectors built on III-nitride waveguides, in which photons are coupled laterally with the help of a tapered optical fibre. This new - geometry should allow near-unity absorption probability in a wide spectral range, since the substrate is transparent to visible and infrared light. The project success will be proven by the realization of a working prototype which will greatly - outperform state-of-the-art single-photon detectors. - - 2017-06-30, closed project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - SuSiPOD - - - H2020-MSCA-IF-2014 - - - 657497 - - - - - ERNST-MORITZ-ARNDT-UNIVERSITÄT GREIFSWALD - ERNST-MORITZ-ARNDT-UNIVERSITÄT GREIFSWALD - UNIVERSITATSMEDIZIN GREIFSWALD KORPERSCHAFT DES OFFENTLICHEN RECHTS - - - EUR 1 491 250 - - - Nanomethods to understand what makes an endogenous protein immunogenic - - - EUR 1 491 250 - - - Germany - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - One of the major challenges in understanding the complex immune system is the question when and why this defense system attacks endogenous proteins (i.e. self-proteins). Currently, there are no reliable methods to predict what - induces such an immune response, despite it has a major impact in medicine by causing autoimmune diseases, and in biotechnology by inducing adverse reactions towards new drugs. - - 2020-03-31, ongoing project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - PredicTOOL - - - ERC-2014-STG - - - 637877 - - - - - KUNGLIGA TEKNISKA HOEGSKOLAN - KUNGLIGA TEKNISKA HOEGSKOLAN - - - EUR 1 499 952 - - - Greening the Poles: Science, the Environment, and the Creation of the Modern Arctic and Antarctic - - - EUR 1 499 952 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project investigates how and why environmental concerns have become so important to our conceptions of the polar regions today. Through a historical study of both the Arctic and Antarctic from 1945 to the turn of the past - century, the project explores the connections between how environments are described - particularly through the natural sciences and economics - and the judgments made about how those environments should be administered. The key hypothesis of this - project is that the process of describing an environment cannot be separated from the process of controlling and managing it. Changing perceptions of concepts such as development, ecological fragility, and wilderness have provided frames for - describing and understanding the polar regions. Why has natural resource extraction been deemed appropriate (or even necessary) in some contexts, and wholly forbidden in others? Why did the concept of sustainable development become important during - the 1980s? Can we think of scientific research programs as instruments of colonialism? And why did national parks and conservation agreements become politically useful? GRETPOL will produce a new understanding of how far from being the passive frames - for human action, environments (in the polar regions but indeed also beyond) are constructed by human agency. As anthropogenic climate change reduces polar ice extent and threatens the entire globe, the question has never been timelier. - - 2022-01-31, ongoing project - - - 2017-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Sweden - - - GRETPOL - - - ERC-2016-STG - - - 716211 - - - - - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - - - EUR 1 500 000 - - - Electron quantum optics in Graphene - - - EUR 1 500 000 - - - France - France - - - Research Organisations - Research Organisations - - Quantum computing is based on the manipulation of quantum bits (qubits) to enhance the efficiency of information processing. In solid-state systems, two approaches have been explored: - - - 2021-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - COHEGRAPH - - - ERC-2015-STG - - - 679531 - - - - - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 999 805,42 - - - Dynamic Nuclear Polarization at ultra-fast sample spinning and ultra-low temperature - - - EUR 1 999 805,42 - - - France - France - France - - - Research Organisations - Research Organisations - Research Organisations - - The goal of the project is to develop a new hyperpolarization approach called Magic Angle Spinning Dynamic Nuclear Polarization (MAS-DNP) to reach levels of sensitivity and resolution that have never been achieved, in order to - tackle highly relevant chemical and biological questions that remain unanswered so far. Firstly this will provide major advances in NMR crystallography (solving 3D structures by NMR) by showing that distance measurements between nuclei (13C, 15N, - etc.) as well as 17O quadrupolar parameters can be extracted from NMR measurements without requiring isotopic labeling. This will be applied to systems that cannot be easily isotopically enriched and for which X-ray analysis is often not suitable. - Secondly we propose an innovative strategy to hyperpolarize nuclear spins using MAS-DNP: rather than polarizing the entire system uniformly, we will selectively “light up” regions where we wish to gather important structural information. This will be - developed to study protein-ligand interactions (with unprecedented resolution) to answer specific structural questions and potentially impact the field of drug engineering. Finally we will show that the unique experimental setup developed in this - project will open up NMR to the routine study of “exotic”, yet ubiquitous and highly informative, nuclei such as 43Ca and 67Zn. Specifically, we will show that MAS-DNP can become a choice technique for the study of diamagnetic metal binding sites, - complementing EPR for the study of metalloproteins. These goals will be achieved thanks to the development of original methods and advanced instrumentation, allowing sustainable access to low temperatures (down to 10-20 K) and fast pneumatic sample - spinning, under microwave irradiation. We expect to improve the current sensitivity to such an extent that 4 orders of magnitude of experimental timesavings are obtained, resulting in completely new research directions and regimes. - - 2021-06-30, ongoing project - - - 2016-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - France - - - ULT-MAS-DNP - - - ERC-2015-CoG - - - 682895 - - - - - KATHOLIEKE UNIVERSITEIT LEUVEN - KATHOLIEKE UNIVERSITEIT LEUVEN - UNIVERSITY OF LEEDS - - - EUR 2 605 897 - - - Astrochemistry of old stars:direct probing of unique chemical laboratories - - - EUR 2 605 897 - - - Belgium - Belgium - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The gas and dust in the interstellar medium (ISM) drive the chemical evolution of galaxies, the formation of stars and planets, and the synthesis of complex prebiotic molecules. The prime birth places for this interstellar - material are the winds of evolved (super)giant stars. These winds are unique chemical laboratories, in which a large variety of gas and dust species radially expand away from the star. - - 2020-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Belgium - - - AEROSOL - - - ERC-2014-CoG - - - 646758 - - - - - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - - - EUR 1 839 633,77 - - - Stars: dynamical Processes driving tidal Interactions, Rotation and Evolution - - - EUR 1 839 633,77 - - - France - France - - - Research Organisations - Research Organisations - - The rotational dynamics of stars strongly impacts their evolution and those of their planetary and galactic environment. Space helio- and asteroseismology recently allowed an observational revolution in this domain. They - revealed, e.g., that the core of the Sun is close to a uniform rotation while those of subgiant and red giant stars slow down drastically during their evolution. These important results demonstrate that powerful dynamical mechanisms (internal waves, - magnetic fields, turbulence) are in action to extract angular momentum all along the evolution of stars. - - 2020-08-31, ongoing project | - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - France - - - SPIRE - - - ERC-2014-CoG - - - 647383 - - - - - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - STOCKHOLMS UNIVERSITET - - - EUR 1 495 476 - - - Emergent spacetime and maximally spinning black holes - - - EUR 1 495 476 - - - France - France - Sweden - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - - One of the greatest challenges of theoretical physics is to understand the fundamental nature of gravity and how it is reconciled with quantum mechanics. Black holes indicate that gravity is holographic, i.e. it is emergent, - together with some of the spacetime dimensions, from a lower-dimensional field theory. The emergence mechanism has just started to be understood in certain special contexts, such as AdS/CFT. However, very little is known about it for the spacetime - backgrounds relevant to the real world, due mainly to our lack of knowledge of the underlying field theories. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - Emergent-BH - - - ERC-2015-STG - - - 679278 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 476 000 - - - Spin-orbit mechanism in adaptive magnetization-reversal techniques, for magnetic memory design - - - EUR 1 476 000 - - - France - France - - - Research Organisations - Research Organisations - - Compared to existing Random Access Memories, the Magnetic RAM (MRAM) has the advantage of being non-volatile. Though the basic requirements for reading and writing a single memory element are fulfilled, the present approach - based on Spin Transfer Torque (STT) suffers from an innate lack of flexibility. - - - 2020-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - SMART DESIGN - - - ERC-2014-STG - - - 638656 - - - - - CHALMERS TEKNISKA HOEGSKOLA AB - CONSIGLIO NAZIONALE DELLE RICERCHE - RIJKSUNIVERSITEIT GRONINGEN - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - UNIVERSITAET BASEL - THE UNIVERSITY OF MANCHESTER - FUNDACIO INSTITUT CATALA DE NANOCIENCIA I NANOTECNOLOGIA - UNIVERSITE CATHOLIQUE DE LOUVAIN - UNIVERSITAET REGENSBURG - RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - AIXTRON LIMITED - GESELLSCHAFT FUR ANGEWANDTE MIKRO UND OPTOELEKTRONIK MIT BESCHRANKTERHAFTUNG AMO GMBH - ALCATEL-LUCENT DEUTSCHLAND AG - AALTO-KORKEAKOULUSAATIO - POLITECNICO DI MILANO - UNIVERSITE DES SCIENCES ET TECHNOLOGIES DE LILLE - LILLE I - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - THALES SA - UNIVERSITAT AUTONOMA DE BARCELONA - DANMARKS TEKNISKE UNIVERSITET - NOKIA OYJ - STMICROELECTRONICS SRL - Teknologian tutkimuskeskus VTT Oy - VARTA MICRO INNOVATION GMBH - GRAPHENEA SA - UNIVERSITE DE STRASBOURG - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - AVANZARE INNOVACION TECNOLOGICA SL - TECHNISCHE UNIVERSITAT HAMBURG-HARBURG - POLITECNICO DI TORINO - ALBERT-LUDWIGS-UNIVERSITAET FREIBURG - AIRBUS OPERATIONS SL - TECHNOLOGICAL EDUCATIONAL INSTITUTE OF CRETE - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA - CENTRO DE INVESTIGACION COOPERATIVADE ENERGIAS ALTERNATIVAS FUNDACION - REPSOL SA - SABANCI UNIVERSITESI - UMEA UNIVERSITET - FONDAZIONE BRUNO KESSLER - TECHNISCHE UNIVERSITAET DRESDEN - STICHTING KATHOLIEKE UNIVERSITEIT - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - LINKOPINGS UNIVERSITET - UNIVERSITAT ZURICH - TECHNISCHE UNIVERSITAET CHEMNITZ - FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG - INSTYTUT TECHNOLOGII MATERIALOW ELEKTRONICZNYCH - UNIVERSITA DEGLI STUDI DI TRIESTE - UNIVERSITAET BREMEN - UNIVERSIDAD DE CASTILLA - LA MANCHA - KAROLINSKA INSTITUTET - EIDGENOSSISCHE MATERIALPRUFUNGS- UND FORSCHUNGSANSTALT - UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN - UNIVERSITE DE GENEVE - TECHNISCHE UNIVERSITEIT DELFT - Eidgenössische Technische Hochschule Zürich - NPL MANAGEMENT LIMITED - OXFORD INSTRUMENTS NANOTECHNOLOGY TOOLS LIMITED - LANCASTER UNIVERSITY - UNIVERSITAET HAMBURG - NOKIA R&D (UK) LIMITED - STIFTELSEN CHALMERS INDUSTRITEKNIK - GRUPO ANTOLIN-INGENIERIA SA - FUNDACIO INSTITUT DE CIENCIES FOTONIQUES - TECHNISCHE UNIVERSITAET WIEN - Asociacion - Centro de Investigacion Cooperativa en Nanociencias - CIC NANOGUNE - UNIVERSIDADE DO MINHO - PANEPISTIMIO IOANNINON - CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL - TECHNISCHE UNIVERSITAET MUENCHEN - FUNDACION IMDEA NANOCIENCIA - FONDATION EUROPEENNE DE LA SCIENCE - SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI DI TRIESTE - UNIVERSITE DE MONTPELLIER - UNIVERSIDAD DE ZARAGOZA - LABORATOIRE NATIONAL DE METROLOGIE ET D'ESSAIS - HORIBA FRANCE SAS - UNIVERSITE DE NAMUR ASBL - KARLSRUHER INSTITUT FUER TECHNOLOGIE - FRIEDRICH-SCHILLER-UNIVERSITAT JENA - PIXIUM VISION - UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6 - CENTRO DE INVESTIGACION BIOMEDICA EN RED - GUGER TECHNOLOGIES OG - CONSORCI INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER - UNIVERSITAET BIELEFELD - UNIVERSITAET ULM - BASF SE - CNM TECHNOLOGIES GMBH - FUNDACION TECNALIA RESEARCH & INNOVATION - POLYMEM - UNIVERSITY COLLEGE LONDON - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - AMALYST LIMITED - UNIVERSITA DEGLI STUDI DI PADOVA - UNIWERSYTET WARSZAWSKI - BRETON SPA - TECHNISCHE UNIVERSITEIT EINDHOVEN - DSM Ahead BV - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA - USTAV FYZIKALNI CHEMIE J. HEYROVSKEHO AV CR, v. v. i. - G24 POWER LIMITED - ITALCEMENTI FABBRICHE RIUNITE CEMENTO SPA - ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA - TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY - ATHERM - UNIVERSITE LIBRE DE BRUXELLES - SELEX ES SPA - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - EPCOS AG - THE UNIVERSITY OF NOTTINGHAM - THE UNIVERSITY OF SHEFFIELD - ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOMATERIALES- CIC biomaGUNE - UNIVERSITA DI PISA - ISTITUTO NAZIONALE DI FISICA NUCLEARE - MAGYAR TUDOMANYOS AKADEMIA ENERGIATUDOMANYI KUTATOKOZPONT - PANEPISTIMIO KRITIS - Institute of Mechanics, Bulgarian Academy of Sciences - BELARUSIAN STATE UNIVERSITY - UNIVERSITA DEGLI STUDI DI SALERNO - ITA-SUOMEN YLIOPISTO - RESEARCH AND DEVELOPMENT OF NANOMATERIALS AND NANOTECHNOLOGY NANO TECHLAB LTD - QUEEN MARY UNIVERSITY OF LONDON - PROGNOMICS LTD - INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM - ERICSSON AB - CONSORZIO NAZIONALE INTERUNIVERSITARIO PER LE TELECOMUNICAZIONI - LIBRE SOCIETA A RESPONSABILITA LIMITATA - GRINP SRL - DYESOL ITALIA SRL - TARTU ULIKOOL - N VISION SYSTEMS AND TECHNOLOGIES SL - UNIVERSITAET AUGSBURG - UNIVERSITY OF SUNDERLAND - CENTRO RICERCHE FIAT SCPA - INSTITUTO DE TECNOLOGIAS EMERGENTES DE LA RIOJA - NANESA SRL - DELTA TECH SPA - ABB AB - INTERNACIONAL DE COMPOSITES SA - ALCATEL-LUCENT ITALIA S.P.A. - FUNDACION PARA LA INVESTIGACION, DESARROLLO Y APLICACION DE MATERIALES COMPUESTOS - FLEXENABLE LIMITED - INFINEON TECHNOLOGIES AG - M-SOLV LTD - NANOSC AB - NOVALIA LIMITED - GLAXOSMITHKLINE RESEARCH AND DEVELOPMENT LTD - LEONARDO - SOCIETA PER AZIONI - INSTITUT FUR KORROSIONSSCHUTZ DRESDEN GMBH - ROBERT BOSCH GMBH - EMBERION OY - Emberion Ltd - NOKIA SOLUTIONS AND NETWORKS UK LIMITED - - - EUR 89 000 000 - - - Graphene-based disruptive technologies - - - EUR 89 000 000,10 - - - Sweden - Italy - Netherlands - Spain - Switzerland - United Kingdom - Spain - Belgium - Germany - Germany - France - United Kingdom - Germany - Germany - Finland - 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Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - This project is the second in the series of EC-financed parts of the Graphene Flagship. The Graphene Flagship is a 10 year research and innovation endeavour with a total project cost of 1,000,000,000 euros, funded jointly by - the European Commission and member states and associated countries. The first part of the Flagship was a 30-month Collaborative Project, Coordination and Support Action (CP-CSA) under the 7th framework program (2013-2016), while this and the - following parts are implemented as Core Projects under the Horizon 2020 framework. - - 2018-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2."> - - - FETFLAGSHIP - FETFLAGSHIP - - - SGA-RIA - SGA-RIA - - - Sweden - - - GrapheneCore1 - - - H2020-Adhoc-2014-20 - - - 696656 - - - - - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - - - EUR 1 497 411 - - - non-LinEar sigNal processing for solving data challenges in Astrophysics - - - EUR 1 497 411 - - - France - France - - - Research Organisations - Research Organisations - - Astrophysics has arrived to a turning point where the scientific exploitation of data requires overcoming challenging analysis issues, which mandates the development of advanced signal processing methods. In this context, - sparsity and sparse signal representations have played a prominent role in astrophysics. Indeed, thanks to sparsity, an extremely clean full-sky map of the Cosmic Microwave Background (CMB) has been derived from the Planck data [Bobin14], a European - space mission that observes the sky in the microwave wavelengths. This led to a noticeable breakthrough: we showed that the large-scale statistical studies of the CMB can be performed without having to mask the galactic centre anymore thanks to the - achieved high quality component separation [Rassat14]. - - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - LENA - - - ERC-2015-STG - - - 678282 - - - - - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - - - EUR 1 500 000 - - - Interpreting Dust Polarization Maps to Characterize the Role of the Magnetic Field in Star Formation Processes - - - EUR 1 500 000 - - - France - France - - - Research Organisations - Research Organisations - - "Rotation and angular momentum transport play a critical role in the formation and evolution of astrophysical objects, including the fundamental bricks of astrophysical structures: stars. Stars like our Sun form when rotating - dense cores, in the interstellar medium, collapse until they eventually reach temperatures at which nuclear fusion begins; while planets, including the Earth, form in the rotationally supported disks around these same young stars. One of the major - challenges of modern astrophysics is the “angular momentum problem"": observations show that a typical star-forming cloud needs to reduce its specific angular momentum by 5 to 10 orders of magnitude to form a typical star such as our Sun. It is also - crucial to solve the angular momentum problem to understand the formation of protoplanetary disks, stellar binaries and the initial mass function of newly formed stars. Magnetic fields are one of the key ways of transporting angular momentum in - astrophysical structures: understanding how angular momentum is transported to allow star formation requires characterizing the role of magnetic fields in shaping the dynamics of star-forming structures. The MagneticYSOs project aims at - characterizing the role of magnetic field in the earliest stage of star formation, during the main accretion phase. - - 2021-06-30, ongoing project - - - 2016-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - MagneticYSOs - - - ERC-2015-STG - - - 679937 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 195 454,80 - - - Mapping an uncertain future: Social and spatial change in conflicting Syria - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - This research project in Human Geography aims at understanding the spatial and social dynamics of the Syrian conflict (from 2011 onwards). It focuses particularly on the local dimension of both the dynamics of the uprising, - the political mobilisations, and the militarisation of the conflict, as well as on the different types of local networks and local organisations and forms of governance that developed since. Looking at the dynamics of the current crisis ‘from the - ground’ helps indeed our understanding of the current spatial and social reorganisations. - - 2017-08-31, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - FUTURESYRIA - - - H2020-MSCA-IF-2014 - - - 658133 - - - - - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - - - EUR 173 076 - - - Production and decay of Hypernuclei by using an intense heavy-ion beam incidenting on a Proton target - - - EUR 173 076 - - - France - - - Research Organisations - - A new hypernuclei program based on the exclusive measurement of (p, ΛK) reactions in inverse kinematics is proposed. The program is to be held at the heavy-ion beam facility GSI, Germany. GSI is the only facility worldwide - where this measurement can be performed. It is considered as a first step towards a world-unique program dedicated to the population and spectroscopy of exotic hypernuclei at the future FAIR facility. - - 2018-05-31, ongoing project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - ProHyPro - - - H2020-MSCA-IF-2015 - - - 705023 - - - - - HEINRICH-HEINE-UNIVERSITAET DUESSELDORF - HEINRICH-HEINE-UNIVERSITAET DUESSELDORF - - - EUR 2 393 447,50 - - - Early Microbial Evolution - - - EUR 2 393 447,50 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - From the primordial emergence of the earliest cells to the ongoing diversification of modern microbiota, the mechanisms that underlie the origin of major prokaryotic groups are still poorly understood. In principle, the origin - of both species and higher taxa among prokaryotes should entail similar mechanisms — ecological interactions with the environment paired with natural genetic variation involving lineage-specific gene innovations and lineage-specific gene - acquisitions. Because eukaryotes started out as a prokaryote lineage, the same holds true at the prokaryote-eukaryote transition. Prokaryotic higher taxa are currently circumscribed by phylogenomic studies encompassing 30-40 proteins for information - processing that are universal to all genomes, or nearly so. The core is useful in taxonomy but comprises only about 1% of an average genome. It does not predict gene content in the remaining 99% of the genome, because of the role of lateral gene - transfer (LGT) in generating diversity within and between prokaryotic groups. Especially in groups with large pangenomes or broad ecological diversity, the core itself does not reveal which gene innovations underlie the origin of major groups, but - gene distributions might. This proposal aims to harness all the evolutionary data that genomes have to offer — gene trees, gene distributions, and split distributions across sets of trees — to chart the history of the 99% component of microbial - genome evolution and the role of LGT in the origin of higher microbial taxa. The focus is on three important questions: i) What are the quantitative and lineage specific relative contributions of gene transfer from endosymbionts vs. gene transfers - from other prokaryotes during eukaryotic genome evolution, ii) Are there significant differences in verticality in comparisons of genome evolution in prokaryotes vs. eukaryotes and how can we statistically better quantify them, and iii) What was the - biological nature of the earliest prokaryotes. - - 2020-10-31, ongoing project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - eMicrobevol - - - ERC-2014-ADG - - - 666053 - - - - - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - - - EUR 2 499 746,66 - - - The cerebral representation of sequences and roles : investigating the origins of human uniqueness. - - - EUR 2 499 746,66 - - - France - France - - - Research Organisations - Research Organisations - - What are the origins of humans’ remarkable capacities to grasp, memorize, and produce complex sequences and rules, as manifested in language and mathematics? During its evolution, the human brain may have acquired a capacity - to represent nested rules, based in part on the expansion of circuits involving the inferior frontal gyrus. This hypothesis will be tested using behavioral measures, functional MRI, magneto-encephalography (MEG), electro-corticography (ECOG) and - machine learning techniques in human and non-human primates tested in identical paradigms. - - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - France - - - NeuroSyntax - - - ERC-2015-AdG - - - 695403 - - - - - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - - - EUR 2 500 000 - - - CMOS/magnetoelectronic Integrated Circuits wil Multifunctional Capabilities - - - EUR 2 500 000 - - - France - France - - - Research Organisations - Research Organisations - - Spin Transfer Torque Magnetic memories (STT-MRAM) are receiving a growing R&D effort within the microelectronic industry aiming at the replacement of DRAM or SRAM at sub-20nm nodes. - - - 2020-10-31, ongoing project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - France - - - MAGICAL - - - ERC-2014-ADG - - - 669204 - - - - - KUNGLIGA TEKNISKA HOEGSKOLAN - KUNGLIGA TEKNISKA HOEGSKOLAN - - - EUR 1 498 729 - - - Bottom-up hybrid control and planning synthesis with application to multi-robot multi-human coordination - - - EUR 1 498 729 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Current control applications necessitate the treatment of systems with multiple interconnected components, rather than the traditional single component paradigm that has been studied extensively. The individual subsystems may - need to fulfil different and possibly conflicting specifications in a real-time manner. At the same time, they may need to fulfill coupled constraints that are defined as relations between their states. Towards this end, the need for methods for - decentralized control at the continuous level and planning at the task level becomes apparent. We aim here towards unification of these two complementary approaches. Existing solutions rely on a top down centralized approach. We instead consider here - a decentralized, bottom-up solution to the problem. The approach relies on three layers of interaction. In the first layer, agents aim at coordinating in order to fulfil their coupled constraints with limited communication exchange of their state - information and design of appropriate feedback controllers; in the second layer, agents coordinate in order to mutually satisfy their discrete tasks through exchange of the corresponding plans in the form of automata; in the third and most - challenging layer, the communication exchange for coordination now includes both continuous state and discrete plan/abstraction information. The results will be demonstrated in a scenario involving multiple (possibly human) users and multiple robots. - - 2020-02-29, ongoing project - - - 2015-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Sweden - - - BUCOPHSYS - - - ERC-2014-STG - - - 639365 - - - - - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - - - EUR 2 554 923,90 - - - Neural mechanisms of learning in the infant brain : from Statistics to Rules and Symbols - - - EUR 2 554 923,90 - - - France - France - - - Research Organisations - Research Organisations - - Infant is the most powerful learner: He learns in a few months to master language, complex social interactions, etc. Powerful statistical algorithms, simultaneously acting at the different levels of functional hierarchies have - been proposed to explain learning. I propose here that two other elements are crucial. The first is the particular human cerebral architecture that constrains statistical computations. The second is the human’s ability to access a rich symbolic - system. I have planned 6 work packages using the complementary information offered by non-invasive brain-imaging techniques (EEG, MRI and optical topography) to understand the neural bases of infant statistical computations and symbolic competence - from 6 months of gestation up until the end of the first year of life. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - France - - - Babylearn - - - ERC-2015-AdG - - - 695710 - - - - - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - - - EUR 2 098 157,50 - - - The Hall Plateau Transition and non-unitary Quantum Field Theory - - - EUR 2 098 157,50 - - - France - France - - - Research Organisations - Research Organisations - - I propose to solve the Quantum Field Theory (QFT) describing the transition between plateaus of quantized Hall conductance in the Integer Quantum Hall Effect (IQHE). - - - 2020-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - France - - - NuQFT - - - ERC-2014-ADG - - - 669205 - - - - - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - - - EUR 1 500 000 - - - Probing quantum fluctuations of single electronic channels in model interacting systems - - - EUR 1 500 000 - - - France - France - - - Research Organisations - Research Organisations - - The fluctuation-dissipation theorem is a prominent milestone in Physics: It links the dissipative response of a physical system to its fluctuations, and provides a microscopic understanding of macroscopic irreversibility. - Recent theoretical advances that have generalized the original fluctuation-dissipation theorem to non-linear quantum systems even far from equilibrium, ask for an experimental test, which is the aim of the project. We will measure the current - fluctuations and dissipative response of driven quantum systems whose non-linearity arises from strong interactions. We will exploit the flexibility offered by nano-patterned high purity 2D electron gases in order to realize single electron channels - in different regimes: 1/ interacting strongly with a single electromagnetic mode (Dynamical Coulomb Blockade of a quantum point contact), 2/ interacting with a single magnetic impurity (Kondo effect in quantum dots), 3/ driving the 2D gas in the - fractional quantum Hall effect where current is carried by strongly correlated 1D channels prototypical of Luttinger liquids. Last, we will address a fundamental issue raised in the early days of quantum mechanics: how long does it take for a - particle to cross a classically forbidden barrier? While Wigner-Smith’s theorem links the issue to the density fluctuations within the barrier, the fluctuation-dissipation theorem links it further to a quantum relaxation resistance. A full - investigation of fluctuation-dissipation relations including quantum effects requires measurements at frequencies hf>k_BT. With the available dilution refrigeration techniques it implies measuring in the few GHz range. Since quantum conductors - have an impedance h/e^2~25.8 kohm much larger than the 50ohm impedance of microwave components, new microwave methods able to deal with large impedance values will be developed. They will be based on the extension to finite magnetic field of the - wide-band impedance matching methods recently developed by the PI. - - 2020-04-30, ongoing project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - NSECPROBE - - - ERC-2014-STG - - - 639039 - - - - - UNIVERSITE PARIS DIDEROT - PARIS 7 - UNIVERSITE PARIS DIDEROT - PARIS 7 - - - EUR 1 589 000 - - - Magnetic approaches for Tissue Mechanics and Engineering - - - EUR 1 589 000 - - - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - "While magnetic nanomaterials are increasingly used as clinical agents for imaging and therapy, their use as a tool for tissue engineering opens up challenging perspectives that have rarely been explored. Lying at the - interface between biophysics and nanomedicine, and based on magnetic techniques, the proposed project aims to magnetically design functional tissues and to explore the tissular fate of nanomaterials. Magnetic nanoparticles will be safely introduced - into therapeutic cells, thus allowing them to be remotely manipulated by external magnets. 3D manipulations of the magnetized cells (patented in 2012) will be used to form tissues with a controlled size and shape through the development of a unique - magnetic bioreactor. In a self-integrating all-in-one process, 3D tissue will be shaped from cellular "bricks" without the need for a scaffold. The magnetic tissue will be amenable to mechanical stimulation and in situ imaging at each step of its - maturation. The project is inherently multidisciplinary: - - 2020-12-31, ongoing project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - France - - - MaTissE - - - ERC-2014-CoG - - - 648779 - - - - - UNIVERSITEIT LEIDEN - UNIVERSITEIT LEIDEN - - - EUR 1 807 334 - - - Moralising Misfortune: A comparative anthropology of commercial insurance - - - EUR 1 807 334 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This is a study of the morality of commercial life insurance. What moral issues are raised when commercial companies define responsibilities for misfortune and the appropriateness of entitlements? What are the concerns about - the financialization of life and intimacy? - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - MoralisingMisfortune - - - ERC-2015-CoG - - - 682467 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 500 000 - - - Structural studies of mammalian Cys-loop receptors - - - EUR 1 500 000 - - - France - France - - - Research Organisations - Research Organisations - - In the brain, Cys-loop receptors mediate fast neurotransmission. They function as allosteric signal transducers across the plasma membrane: upon binding of one or more neurotransmitter molecules to an extracellular site, the - receptors undergo complex conformational transitions that result in transient opening of an intrinsic ion channel. The Cys-loop family comprises receptors activated by serotonin, acetylcholine, glycine and GABA. Mammalian receptors are also the - targets of a legion of psycho-active and therapeutic compounds (including nicotine, benzodiazepines, anti-emetics, general anaesthetics). Our structural knowledge is currently limited to invertebrate homologues. Atomic structures mammalian receptors - are therefore acutely missing in order to understand their physiological role in molecular terms, and to be able to develop new drugs targeting them. - - - 2020-05-31, ongoing project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - PentaBrain - - - ERC-2014-STG - - - 637733 - - - - - OSLO UNIVERSITETSSYKEHUS HF - SORIN CRM SAS - UNIVERSITAT POLITECNICA DE VALENCIA - TECHNISCHE UNIVERSITAET DRESDEN - OVESCO ENDOSCOPY AG - NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU - VALOTEC - FUNDACION PARA LA INVESTIGACION DEL HOSPITAL UNIVERSITARIO LA FE DE LA COMUNIDAD VALENCIANA - - - EUR 3 957 045,03 - - - Wireless In-Body Environment - - - EUR 3 957 045,03 - - - Norway - France - Spain - Germany - Germany - Norway - France - Spain - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - - WiBEC (Wireless In-Body Environment Communications) is an Innovative Training Network for 16 young researchers, who will be recruited and trained in coordinated manner by Academia, Industry, and Medical Centres. This training - will address the Social, Health, and Technology challenges of the H2020:Wireless In-Body Devices. WiBEC’s main objective is to provide high quality and innovative doctoral training to develop the wireless technologies for novel implantable devices - that will contribute to the improvement in quality and efficacy of healthcare. Two devices will be used as a focus for the individual researcher’s projects; cardiovascular implants and ingestible capsules to investigate gastro intestinal problems. - These devices will enable medical professionals to have timely clinical information at the point of care. The medical motivation is to increase survival rates and improvement of health outcomes with easy and fast diagnosis and treatment. The goal for - homecare services is to improve quality of life and independence for patients by enabling ambient assisted living (AAL) at home. In this particular ETN, inter-sectoral and multi-discipline work is essential, as the topic requires cooperation between - medical and engineering institutions and industry. This aspect is fulfilled with the participation of two reference hospitals, two medical device manufacturers and three top ranked universities in Europe, covering complementary aspects of the in-body - wireless device field. Concerning future employment perspectives; surgery and medical assistance is rapidly becoming more technological than it is today, and a large number of experts combining engineering and medical skills will be required in - Europe to enable novel paradigms like AAL to be realised. The ESRs who join this ETN will acquire diverse skills that will enable them to occupy privileged positions to join and promote EU leadership in ICT for Health. - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Norway - - - WiBEC - - - H2020-MSCA-ITN-2015 - - - 675353 - - - - - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - - - EUR 264 668,40 - - - Large scale structure of the Universe and fundamental physics - - - EUR 264 668,40 - - - France - - - Research Organisations - - The purpose of this cosmology project is to study the content and evolution of our Universe using the distribution of matter on large scales. A key goal of forthcoming galaxy surveys is probing fundamental physics, such as the - mass of neutrinos and the nature of dark energy, the component sourcing cosmic acceleration. The analysis and interpretation of their data crucially relies on the development of perturbation theory methods and other theoretical tools to describe and - predict the evolution of large scale structures in the universe, particularly in the non-linear regime. This project aims to establish the optimal approach to compute the growth of structures and to extract information about dark energy and neutrino - masses from the data. - - 2020-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - France - - - NLO-CO - - - H2020-MSCA-IF-2015 - - - 706434 - - - - - REGION HOVEDSTADEN - REGION HOVEDSTADEN - - - EUR 2 072 000 - - - Molecular imaging and targeted therapy of the aggressive phenotype: development of uPAR theranostics for cancer patients - - - EUR 2 072 000 - - - Denmark - Denmark - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - For practice of personalized medicine in cancer, non-invasive tools for diagnosing at the molecular level are needed. Molecular imaging methods are capable of this while at the same time circumventing sampling error as the - whole tumor burden is evaluated. - - 2020-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Denmark - - - uPET - - - ERC-2014-ADG - - - 670261 - - - - - UNIVERSITA DEL SALENTO - UNIVERSITA DEL SALENTO - - - EUR 1 488 750 - - - Distributed Optimization Methods for Smart Cyber-Physical Networks - - - EUR 1 488 750 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The combination of embedded electronics and communication capability in almost any mobile or portable device has turned this century into the age of cyber-physical networks. Smart communicating devices with their sensing, - computing and control capabilities promise to make our cities, transportation systems, factories and living environments more intelligent, energy-efficient, safe and secure. This extremely complex system has raised a number of new challenges - involving ICT disciplines. In particular, a novel peer-to-peer distributed computational model is appearing as a new opportunity in which a service is built-up cooperatively by peers, rather than by a unique provider that knows and owns all data. The - interdisciplinary “Optimization Community” is facing this revolution sharing a common need: to find new theories, methodologies and tools to optimize over this complex network system. With this in mind, OPT4SMART has a twofold objective. First, to - provide a comprehensive theoretical framework to solve distributed optimization problems over peer-to-peer networks. Second, to develop effective numerical tools, based on this framework, to solve estimation, learning, decision and control problems - in cyber-physical networks. To achieve this twofold objective, we will take a systems-theory perspective. Specific problems from these four areas will be abstracted to a common mathematical set-up, and addressed by means of interdisciplinary - methodologies arising from a synergic combination of optimization, controls, and graph theories. In particular, OPT4SMART will face the challenge of solving optimization problems under severe communication limitations, very-large-scale problem and - data size, and real-time computational constraints. The expected result will be a combination of strong theoretical methods and effective numerical toolboxes available to people in Engineering, Computer Science, Mathematics and other areas, who are - facing optimization in cyber-physical networks. - - 2020-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Italy - - - OPT4SMART - - - ERC-2014-STG - - - 638992 - - - - - CENTRE TECNOLOGIC DE TELECOMUNICACIONS DE CATALUNYA - UNIVERSITA DEGLI STUDI DI PADOVA - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - ATHONET SRL - UNIVERSITY OF STRATHCLYDE - WORLDSENSING SL - HUAWEI TECHNOLOGIES OY (FINLAND) CO LTD - TOSHIBA RESEARCH EUROPE LIMITED - - - EUR 3 653 723,88 - - - Sustainable CellulAr networks harVEstiNG ambient Energy - - - EUR 3 653 723,88 - - - Spain - Italy - United Kingdom - France - Italy - United Kingdom - Spain - Finland - United Kingdom - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Energy sustainability is key to future mobile networks due to their foreseen capacity upsurge. The objective of the ETN SCAVENGE (Sustainable CellulAr networks harVEstiNG ambient Energy) is to create a training network for early-stage - - 2020-01-31, ongoing project - - - 2016-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Spain - - - SCAVENGE - - - H2020-MSCA-ITN-2015 - - - 675891 - - - - - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - - - EUR 1 318 145 - - - Charge orders, Magnetism and Pairings in High Temperature Superconductors - - - EUR 1 318 145 - - - France - France - - - Research Organisations - Research Organisations - - For nearly thirty years, the search for a room-temperature superconductor has focused on exotic materials known as cuprates, obtained by doping a parent Mott insulator, and which can carry currents without losing energy as - heat at temperatures up to 164 Kelvin. Conventionally three main players were identified as being crucial i) the Mott insulating phase, ii) the anti-ferromagnetic order and iii) the superconducting (SC) phase. Recently a body of experimental probes - suggested the presence of a fourth forgotten player, charge ordering-, as a direct competitor for superconductivity. In this project we propose that the relationship between charge ordering and superconductivity is more intimate than previously - thought and is protected by an emerging SU(2) symmetry relating the two. The beauty of our theory resides in that it can be encapsulated in one simple and universal “gap equation”, which in contrast to strong coupling approaches used up to now, can - easily be connected to experiments. In the first part of this work, we will refine the theoretical model in order to shape it for comparison with experiments and consistently test the SU(2) symmetry. In the second part of the work, we will search for - the experimental signatures of our theory through a back and forth interaction with experimental groups. We expect our theory to generate new insights and experimental developments, and to lead to a major breakthrough if it correctly explains the - origin of anomalous superconductivity in these materials. - - 2021-07-31, ongoing project - - - 2016-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - France - - - CHAMPAGNE - - - ERC-2015-AdG - - - 694651 - - - - - UNIVERSITY OF CYPRUS - ENVIRONMENTAL INSTITUTE s.r.o. - KWR WATER B.V. - THE AGRICULTURAL RESEARCH ORGANISATION OF ISRAEL - THE VOLCANI CENTRE - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - ADVENTECH - ADVANCED ENVIRONMENTAL TECHNOLOGIES LDA - UNIVERSIDADE CATOLICA PORTUGUESA - TECHNISCHE UNIVERSITAET DRESDEN - UNIVERSITA DEGLI STUDI DI SALERNO - TECHNISCHE UNIVERSITAET WIEN - - - EUR 3 708 689,76 - - - ANtibioticS and mobile resistance elements in WastEwater Reuse applications: risks and innovative solutions - - - EUR 3 708 689,76 - - - Cyprus - Slovakia - Netherlands - Israel - Spain - Portugal - Portugal - Germany - Italy - Austria - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In response to the increasing problem of water shortage, the reuse of treated urban wastewater is considered the most suitable and reliable alternative for sustainable water management and agricultural development. In spite of - the benefits associated with this practice, major concerns currently exist, related to the adverse effects regarding chemical and biological contaminants of emerging concern such as antibiotics and mobile antibiotic resistance elements such as - antibiotic resistant bacteria and resistance genes. These are now considered as a serious public health problem by various international organizations and the European Commission, because of their spread in the environment, the food chain, drinking - water, etc. To tackle these problems, scientists with an interdisciplinary research/training background are urgently needed. This ETN will train a new generation of ESRs to address the risks associated with such contaminants and wastewater reuse. - Innovative chemical, microbiological, toxicological and modelling tools, and novel process engineering will form the scientific and training core of their innovative research projects and training. The project will contribute to understanding the - fate and transmission of antibiotics and resistance from wastewater to the environment and humans, through soil, ground/surface water and crops. Relevant ELVs will be determined, essential for the development and implementation of regulatory - frameworks. This project directly tackles these aspects, by bringing together a multidisciplinary research team, with the private sector, and policy makers and through communication activities towards stakeholders and the wider public. - - 2019-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Cyprus - - - ANSWER - - - H2020-MSCA-ITN-2015 - - - 675530 - - - - - SEAGATE SYSTEMS UK LIMITED - ALLINEA SOFTWARE LIMITED - BULL SAS - UNITED KINGDOM ATOMIC ENERGY AUTHORITY - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - DEUTSCHES FORSCHUNGSZENTRUM FUR KUNSTLICHE INTELLIGENZ GMBH - DIAMOND LIGHT SOURCE LIMITED - FORSCHUNGSZENTRUM JULICH GMBH - KUNGLIGA TEKNISKA HOEGSKOLAN - SCIENCE AND TECHNOLOGY FACILITIES COUNCIL - - - EUR 7 882 531 - - - SAGE - - - EUR 7 882 531,25 - - - United Kingdom - United Kingdom - France - United Kingdom - France - Germany - United Kingdom - Germany - Sweden - United Kingdom - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - - Worldwide data volumes are exploding and islands of storage remote from compute will not scale. We will demonstrate the first instance of intelligent data storage, uniting data processing and storage as two sides of the same - rich computational model. This will enable sophisticated, intention-aware data processing to be integrated within a storage systems infrastructure, combined with the potential for Exabyte scale deployment in future generations of extreme scale HPC - systems. - - 2018-08-31, ongoing project | - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.2."> - - - FETHPC-1-2014 - HPC Core Technologies, Programming Environments and Algorithms for Extreme Parallelism and Extreme Data Applications - - - RIA - Research and Innovation action - - - United Kingdom - - - SAGE - - - H2020-FETHPC-2014 - - - 671500 - - - - - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 2 250 000 - - - CONTROLLING AND MEASURING RELATIVISTIC MOTION OF MATTER WITH ULTRAINTENSE STRUCTURED LIGHT - - - EUR 2 250 000 - - - France - France - France - - - Research Organisations - Research Organisations - Research Organisations - - Femtosecond lasers can now provide intensities such that the light field induces relativistic motion of large ensembles of electrons. The ultimate goal of this Ultra-High Intensity (UHI) Physics is the control of relativistic - motion of matter with light, which requires a deep understanding of this extreme regime of laser-matter interaction. Such a control holds the promise of major scientific and societal applications, by providing ultra-compact laser-driven particle - accelerators and attosecond X-ray sources. Until now, advances in UHI Physics have relied on a quest for the highest laser intensities, pursued by focusing optimally-compressed laser pulses to their diffraction limit. In contrast, the goal of the - ExCoMet project is to establish a new paradigm, by demonstrating the potential of driving UHI laser plasma-interactions with sophisticated structured laser beams–i.e. beams whose amplitude, phase or polarization are shaped in space-time. - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - France - - - ExCoMet - - - ERC-2015-AdG - - - 694596 - - - - - ASSOCIACAO DO INSTITUTO SUPERIOR TECNICO PARA A INVESTIGACAO E DESENVOLVIMENTO - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - IMAGINE OPTIC - UNIVERSIDAD POLITECNICA DE MADRID - STICHTING CENTRUM VOOR WISKUNDE EN INFORMATICA - CONSIGLIO NAZIONALE DELLE RICERCHE - - - EUR 3 996 875 - - - volumetric medical x-ray imaging at extremely low dose - - - EUR 3 996 875 - - - Portugal - France - France - France - Spain - Netherlands - Italy - - - Research Organisations - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - - Computerized Tomography (CT) has been one of the greatest achievements in medical imaging, but at the cost of a high, potentially harmful, X-ray irradiation dose. The ultimate goal of VOXEL is to provide an alternative to - tomography with a disruptive technology enabling 3D X-ray imaging at very low dose. VOXEL aims at prototyping new cameras that will combine the X-ray penetration and nanometre spatial resolution, easiness to use, afforded by avoiding the rotation of - the source or the sample, and extremely low dose for maximum impact on medicine and biology. - - - 2019-05-31, ongoing project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-1-2014 - FET-Open research projects - - - RIA - Research and Innovation action - - - Portugal - - - VOXEL - - - H2020-FETOPEN-2014-2015-RIA - - - 665207 - - - - - STICHTING VU - STICHTING VU - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - - - EUR 150 000 - - - Extracting Super-Resolution from Classical Fluorescence Microscopy - - - EUR 150 000 - - - Netherlands - Netherlands - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - The beginning of this century has seen the development of optical super-resolution fluorescence microscopic methods, which yield pictures to resolutions of a few tens of nanometers. This breakthrough has transformed the field - of cellular biology, but relies on approaches generally demanding in terms of optics, and which can be applied only on limited classes of fluorophores. This project aims at preparing the commercialization of a new, simple, and cheap, way of - extracting super-resolution from images obtained with classical confocal fluorescence microscopes. Currently, this approach yields images with a resolution between 80 nm to 50 nm, which can most likely be increased in a near future. This method can - thus be used with any type of fluorophore, just by equipping (confocal) microscopes with a high-end X-Y table and a 2D detector. More complex super-resolution fluorescence microscopic techniques have generated more than 7000 citations in the last - years, mostly in biology, but also in chemistry and material sciences. The proposed technology, which can i) easily be implemented for a limited cost and ii) requires no more maintenance and alignment than classical confocal microscopy, is expected - to be rapidly implemented in a very large number of laboratories, thus generating new knowledge and a vast range of scientific advances. In the frame of this project, which is a direct consequence of the work started in the frame of the PhotProt ERC - advanced grant (id n° 267333), we will in parallel i) improve the performances of this technology by modifying its present design, ii) perform the necessary patenting of this technology, iii) start market studies to evaluate its actual commercial - potential iv) enter in contact with companies devoted to microscope engineering and development, and with detector manufacturers, to raise their interest, and envision under which form this new technology can be commercialized, how to conceive the - corresponding commercial prototype. - - 2016-05-31, closed project - - - 2014-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2014 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Netherlands - - - SUPER-RESOL - - - ERC-2014-PoC - - - 640982 - - - - - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - - - EUR 149 913 - - - SolarPredict: An advanced predictive tool and service of the Solar 11-yr Activity Cycle - - - EUR 149 913 - - - France - France - - - Research Organisations - Research Organisations - - The main idea of the SolarPredict Proof of Concept project is to use physically based dynamo models to make solar 11-yr activity predictions, in particular of Earth impacting events, more robust/reliable and to develop the - tools to make them accessible (with the appropriate licencing and IPR) to customers (such as private corporations or governmental agencies) as a service, software or paid/freemium applications. The key advantage of our tools/techniques over current - ones is both our deep knowledge of the working of the solar dynamo and magnetism and the implementation in solar physics of state-of-the-art variational data assimilation (DA) techniques used daily in weather forecasting. These variational techniques - are known to be more robust and versatile than for instance sequential methods or simple geomagnetic precursors thus allowing us to incorporate the highly complex solar magnetic activity and dynamics into our forecasting tools. Thanks to our advanced - 2-D direct and adjoint mean field dynamo codes and modern DA technique, we will assimilate the most relevant solar observational data (sunspots numbers, polar cap magnetic field, surface flows...) into our prediction model hence allowing us to - develop an operational prototype. Indeed major solar storms are strongly correlated to the intensity of solar cycle and 80% of them are directly due to the presence of complex active regions that are more frequent as the 11-yr cycle intensifies. Thus - being able to anticipate the level and geometry of solar global magnetism give us a competitive edge in predicting major solar storms. We will thus bring with the SolarPredict project, our novel variational DA solar prediction algorithm to a more - mature state such as to make it operational and useful to private companies and governmental agencies in order to help them evaluate the economic cost of solar activity and associated storms and protect their assets by anticipating such devastating - solar activity. - - 2016-08-31, closed project - - - 2015-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2014 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - France - - - SolarPredict - - - ERC-2014-PoC - - - 640997 - - - - - POLITECHNIKA SLASKA - UNIVERSITY OF STRATHCLYDE - KAUNO TECHNOLOGIJOS UNIVERSITETAS - POLITECHNIKA LODZKA - UNIVERSITY OF DURHAM - CENTITVC - CENTRO DE NANOTECNOLOGIA E MATERIAIS TECNICOS FUNCIONAIS E INTELIGENTES ASSOCIACAO - OSSILA LIMITED - AIXTRON SE - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 3 717 198,72 - - - Donor-Acceptor light emitting exciplexes as materials for easily to tailor ultra-efficient OLED lighting - - - EUR 3 717 198,72 - - - Poland - United Kingdom - Lithuania - Poland - United Kingdom - Portugal - United Kingdom - Germany - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - - Artificial lighting is a global and growing industry. New forms of efficient solid state lighting (SSL) in particular are rapidly gaining a market share. New OLED technologies (Organic Light Emitting Diode) can revolutionise - this industry as they have done in displays because of their potential flexible structure, infinite tailoring of their properties, efficiency and high colour quality. Industrial forecasts predict that the OLED lighting market will grow from $200 - million in 2015 to $1.7 billion by 2020. In order to fully benefit from this huge market potential, Europe`s academia and industry are eager to develop new technologies and recruit highly qualified staff. - - - 2019-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Poland - - - EXCILIGHT - - - H2020-MSCA-ITN-2015 - - - 674990 - - - - - BANGOR UNIVERSITY - - - EUR 183 454,80 - - - Microbial communities of Temperate, Artic and Tropical peatlands and their role in the response of carbon storage function to global change - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The present proposal aim at understanding microbial role in peatland sensitivity to climate change at a Global Scale. Peatlands represent one of the most important terrestrial carbon pools, despite they only cover 3% of the - earth’s surface they store one third of all terrestrial carbon. This ecosystem has shown to be sensitive to different disturbances in terms of their carbon storage capacity and it is expected a huge CO2 and CH4 release as well as an increase in - dissolved organic carbon exportation to freshwater systems, due to climate change. Peatlands cover large extensions in arctic and temperate zones, but they are also present in tropical regions were their ecology and functioning is almost unknown. Due - to the valuable peatland role as carbon sink there has been many intents to find out the effect of global change on their functioning, however we are still far to totally comprehend and predict this effect, existing important unsolved questions on - the role of microbial decomposer communities (Fungi, Bacteria and Archaea), the structure-function relationship, and so far, none study has assessed the climate change impact at global scale. In order to fill these gaps I propose to survey the - microbial communities in Arctic, Temperate and Tropical peatlands and test how differences in origin-legacy can drive peatlands sensitivity to drought events. The proposed methodology is an interdisciplinary approach (combining molecular thechniques, - ecosystem measurements and biogeochemistry) with three big components: 1) initial field work study to systematically assess microbial communities from the 3 regions; 2) a microcosm experiment to test the effect of drought (water table reduction) on - peatland functioning; 3) a secondment in a drinking water company to put into a management context the results, as these companies are interested in the by-product formation problem thanks to the DOC enhancing in water supplies due to the loss of - peatlands storage capacity. - - 2018-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - MicroPEAT - - - H2020-MSCA-IF-2015 - - - 706616 - - - - - MAGYAR TUDOMANYOS AKADEMIA TARSADALOMTUDOMANYI KUTATOKOZPONT - MAGYAR TUDOMANYOS AKADEMIA TARSADALOMTUDOMANYI KUTATOKOZPONT - - - EUR 1 973 500 - - - No Sword Bites So Fiercly as an Evil Tongue?Gossip Wrecks Reputation, but Enhances Cooperation - - - EUR 1 973 500 - - - Hungary - Hungary - - - Research Organisations - Research Organisations - - Social norms in general, and norms of cooperation in particular, are the cement of all human societies. For the difficult problems of the maintenance and enforcement of social norms and of cooperation, humans have developed - surprisingly complex solutions. Reputation mechanisms and gossip are certainly among the compound informal solutions. - - 2020-11-30, ongoing project - - - 2015-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Hungary - - - EVILTONGUE - - - ERC-2014-CoG - - - 648693 - - - - - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - - - EUR 129 807 - - - Millimeter Wave Massive Arrays enabling RFID/Radar Applications on 5G Smartphones - - - EUR 129 807 - - - France - - - Research Organisations - - Nowadays, a rising interest is moving towards the fifth generation (5G) of wireless mobile communication, as numerous devices and different heterogeneous networks will be interconnected, guaranteeing zero-distance connectivity - between people, devices and objects. To deal with the ever increasing data traffic demand and the low power consumption requirements in the perspective of a sustainable growth, smart solutions have to provide energy- and cost-efficient services. In - this context, the massive antenna arrays deployment in base stations, access points or smartphones, appears like a viable solution to meet these new challenges. Besides communication, the availability of such a technology can also allow other - interesting applications such as accurate simultaneous localization and mapping (SLAM) performed by a personal radar integrated in smartphones, enabling new services in the device-to-device communication. In addition, the interrogation of tagged - objects placed in the environment through radiofrequency identification (RFID) technology will allow a mapping of the real world into the internet space, enabling environment-related applications and constitute the so called smart space within the - Internet of Things concept. Moreover, the reduced wavelength at millimeter-waves (mmW) paves the way for packing a large number of antenna elements into a small area, overcoming the difficult integration of laser-based or mechanical steering devices - into mobiles. - - - 2017-01-19, closed project - - - 2015-07-20 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - MAPS - - - H2020-MSCA-IF-2014 - - - 659067 - - - - - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - - - EUR 1 299 958,26 - - - Strategic Predictions for Quantum Field Theories - - - EUR 1 299 958,26 - - - France - France - - - Research Organisations - Research Organisations - - Ambitious Questions: - - 2020-05-31, ongoing project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - preQFT - - - ERC-2014-STG - - - 639729 - - - - - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - - - EUR 173 076 - - - Dark energy, non-linearites and effective theories - - - EUR 173 076 - - - France - - - Research Organisations - - The objective of this project is improving substantially our understanding of the acceleration of the Universe by developing novel effective techniques and semi-analytical methods for non-linear cosmological perturbation - theory that will be applied to the data of upcoming high precision surveys. The accelerated expansion of the Universe was first detected in 1998 with Type Ia supernova data, and today there is ample evidence for it from various other observations - such as the cosmic microwave background radiation (CMB) and the distribution of galaxies at large scales. We call dark energy the mysterious force that drives the acceleration of the Universe and understanding its origin is one of the major problems - in cosmology of our time. The high precision of the near-future probes designed for elucidating the nature of dark energy needs to be matched with very accurate theoretical predictions, in particular concerning non-linear effects in cosmological - perturbation theory. Developing efficient methods to compute these effects is a crucial requirement for the interpretation of the future dark energy data. I will apply the methods of effective field theories, that have been widely successful in many - areas of physics, to develop new tools for describing dark matter and dark energy perturbations in the linear and non-linear regimes. I will combine these tools with state-of-the-art forecasting techniques to determine the prospects for the detection - of dark energy parameters from future large scale structure data (specifically from Euclid) in combination with CMB data from Planck. - - 2017-09-30, closed project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - DEFT - - - H2020-MSCA-IF-2014 - - - 656794 - - - - - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - POLITECNICO DI MILANO - STICHTING VU - RUHR-UNIVERSITAET BOCHUM - TELEFONICA INVESTIGACION Y DESARROLLO SA - F-SECURE OYJ - - - EUR 702 000 - - - Restoring Trust in the cyber space: a Systems Security Proposal - - - EUR 702 000 - - - Greece - Italy - Netherlands - Germany - Spain - Finland - - - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Fueled by a string of high profile attacks and recent revelations about unprecedented cyber surveillance, interest in systems security is rising-not just among industry and governments, but even among individual citizens - across Europe. Corporate organizations worry about the viability of their businesses, nation states about cyber attacks by other nation states or terrorist groups, and citizens about the trustworthiness of the ICT infrastructures. The long list of - recent security incidents is eroding people's trust in the digital economy and shows that more research is needed. - - 2020-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Greece - - - PROTASIS - - - H2020-MSCA-RISE-2015 - - - 690972 - - - - - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - - - EUR 173 076 - - - Characterizing properties of the interstellar medium to better understand how stars form in galaxies - - - EUR 173 076 - - - France - - - Research Organisations - - The complex interplay between the interstellar medium (ISM) and the stars that it gives birth to is central to studies of galaxy evolution. The properties of the ISM, and especially its capacity to cool, determine when and - where star formation occurs. Those properties are well-known in the Milky Way but not in external galaxies. Only recently has the extragalactic community dedicated effort to obtain very rich archives of the ISM tracers (dust, CO and now [CII]) from - both space and ground based observatories, but we currently lack a detailed multi-wavelength and multiphase modeling that can exploit the data in a self-consistent way. - - 2019-01-31, ongoing project - - - 2017-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - eGALISM - - - H2020-MSCA-IF-2015 - - - 702622 - - - - - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - - - EUR 261 957,60 - - - Inter-individual variability in learning: an investigation of its determinants - - - EUR 261 957,60 - - - France - - - Research Organisations - - The ability to extract regularities from the environment (statistical learning) is an essential feature of the primate brain. While inter-individual differences exist in statistical learning capacity in humans, little is know - as to their origins. The present project proposes to investigate the cognitive and neural determinants of these differences, and to ask what their impact might be on the acquisition of a foundational skill for education, i.e. reading. - - - 2018-04-30, ongoing project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - France - - - LearningDeterminants - - - H2020-MSCA-IF-2014 - - - 661667 - - - - - DUBLIN CITY UNIVERSITY - THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS - UNIVERSITEIT GENT - CENTRO DE ESTUDOS SOCIAIS - OXFORD BROOKES UNIVERSITY - FORSCHUNGSSTELLE FUR UNABHANGIGE LITERATUR UND GESELLSCHAFTLICHE BEWEGUNGEN OSTEUROPAS AN DER UNIVERSITAT BREMEN - TALLINNA TEHNIKAULIKOOL - - - EUR 3 811 357,08 - - - Around the Caspian: a Doctoral Training for Future Experts in Development and Cooperation with Focus on the Caspian Region - - - EUR 3 811 357,08 - - - Ireland - United Kingdom - Belgium - Portugal - United Kingdom - Germany - Estonia - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - - The main goal of this project is to train the next generation of experts on the Caspian region in order to establish, and make sustainable, a network of excellence. This will be achieved through an integrated PhD programme on - the Caspian that boosts the researchers’ theoretical, empirical and administrative skills, a thing that will make them extremely competitive for employment in both academic and non-academic sectors but also confident and knowledgeable enough to start - their own projects. The training will enhance the research skills of the ESRs while also giving them a first-hand experience with a partner operating in a different environment, thus learning how to apply their skills to different fields and sectors. - We expect our network and training to become a leading voice on issues related to the Caspian region both in academia and other sectors. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Ireland - - - CASPIAN - - - H2020-MSCA-ITN-2014 - - - 642709 - - - - - INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT - CENTRE DE COOPERATION INTERNATIONALE EN RECHERCHE AGRONOMIQUE POUR LEDEVELOPPEMENT - C.I.R.A.D. EPIC - UNIVERSITE RENNES II - UNIVERSITAET INNSBRUCK - STIFTELSEN THE STOCKHOLM ENVIRONMENT INSTITUTE - LANCASTER UNIVERSITY - Instituto Superior de Agronomia - LISODE SARL - GEOMATYS - VIEIRA PAK MANUELA - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSITE DE GUYANE - UNIVERSITE DE MONTPELLIER - UNIVERSITE PAUL SABATIER TOULOUSE III - - - EUR 1 705 500 - - - OBSERVATORY OF THE DYNAMICS OF INTERACTIONS BETWEEN SOCIETIES AND ENVIRONMENT IN THE AMAZON - - - EUR 1 849 500 - - - France - France - France - Austria - Sweden - United Kingdom - Portugal - France - France - France - France - France - France - France - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Achieving a sustainable development trajectory in Amazonia is one of the key challenges facing Brazil, and is also an important international concern. ODYSSEA assembles an internationally renowned European and Brazilian - multidisciplinary and intersectoral team. We aim to produce fundamental science and tools in order to build an innovative multi-and interdisciplinary observatory to monitor and assess dynamic interactions between Amazon societies and their - environments. This observatory will serve as a basis for policy development that integrates social, environmental, political-economic and human health dimensions. Our methodology puts the society at the heart of the observatory’s building process, - engaging stakeholders and decision makers in the research to favour advancement of their objectives and commitment to sustainable development issues. - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - France - - - ODYSSEA - - - H2020-MSCA-RISE-2015 - - - 691053 - - - - - CONSIGLIO NAZIONALE DELLE RICERCHE - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - STIFTUNG DEUTSCHES ELEKTRONEN-SYNCHROTRON DESY - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - INSTALLATION EUROPEENNE DE RAYONNEMENT SYNCHROTRON - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - FORSCHUNGSZENTRUM JULICH GMBH - FUNDACIO INSTITUT CATALA DE NANOCIENCIA I NANOTECNOLOGIA - KARLSRUHER INSTITUT FUER TECHNOLOGIE - LUNDS UNIVERSITET - Promoscience srl - FUNDACIO PRIVADA PARC DE RECERCA UAB - PAUL SCHERRER INSTITUT - SCIENCE AND TECHNOLOGY FACILITIES COUNCIL - TECHNISCHE UNIVERSITAET GRAZ - TECHNISCHE UNIVERSITAET MUENCHEN - UNIVERSITA DEGLI STUDI DI MILANO - UNIVERZA V NOVI GORICI - UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA - - - EUR 9 994 861 - - - NANOSCIENCE FOUNDRIES AND FINE ANALYSIS - EUROPE - - - EUR 11 759 061 - - - Italy - France - France - Germany - Switzerland - France - Greece - Germany - Spain - Germany - Sweden - Italy - Spain - Switzerland - United Kingdom - Austria - Germany - Italy - Slovenia - Spain - - - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - NFFA-EUROPE will implement the first open-access research infrastructure as a platform supporting comprehensive projects for multidisciplinary research at the nanoscale extending form synthesis to nanocharacterization to - theory and numerical simulation. The integration and the extension of scope of existing specialized infrastructures within an excellence network of knowledge and know-how will enable a large number of researchers from diverse disciplines to carry out - advanced proposals impacting science and innovation. The full suite of key infrastructures for nanoscience will become, through the NFFA-EUROPE project, accessible to a broader community extended to research actors operating at different levels of - the value chain, including SMEs and applied research, that are currently missing the benefits of these enabling technologies. NFFA-EUROPE sets out to offer an integrated, distributed infrastructure to perform comprehensive nanoscience and - nanotechnology projects from synthesis and nanolithography (with nanofoundry installations) to advanced characterization and theoretical modellization/numerical simulation (with experimental installations including analytical large scale facilities - and a distributed theoretical installation including high-performance computing). Coordinated access will be given to complementary facilities co-located in nine well distributed main sites in Europe, ensuring the optimal match between user proposal - and technical offer. The research activity of the Consortium will realize innovative solutions on key bottlenecks of nanoscience research, therefore upgrading the facility quality and uniqueness. - - 2019-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.2."> - - - INFRAIA-1-2014-2015 - Integrating and opening existing national and regional research infrastructures of European interest - - - RIA - Research and Innovation action - - - Italy - - - NFFA-Europe - - - H2020-INFRAIA-2014-2015 - - - 654360 - - - - - KOBENHAVNS UNIVERSITET - UNIVERSITY COLLEGE LONDON - KAROLINSKA INSTITUTET - THE ROYAL VETERINARY COLLEGE - UNIVERSITAIR MEDISCH CENTRUM UTRECHT - NORDIC BIOSCIENCE COMPOUND DEVELOPMENT A/S - Grünenthal GmbH - - - EUR 3 558 676,32 - - - European Training Network on Bone Pain - - - EUR 3 558 676,32 - - - Denmark - United Kingdom - Sweden - United Kingdom - Netherlands - Denmark - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The aim is to create an innovative European PhD training network in bone pain. Millions in Europe and beyond suffer from bone pain, a debilitating complication of many musculoskeletal disorders such as arthritis and bone - metastasis. However, being a truly multidisciplinary subject spanning neuroscience, bone biology, and even cancer research, it demands a multidisciplinary approach. Despite a huge negative impact on the quality of life of the patients and on society - as a whole, no specific treatment is available. To address this societal challenge and the strong innovation potential, we want to form the first European platform to promote frontline research, innovation and education within bone pain. The network - encompasses 5 academic and 2 industrial beneficiaries and 1 industrial partner all committed to creating an outstanding wide-ranging yet integrated training program for early stages researchers to elucidate the mechanisms of bone pain and develop new - medicines. We will use in vivo models of arthritic pain, cancer-induced bone pain and fracture pain to investigate the pathophysiology and novel treatment strategies. In vivo electrophysiology will be used for studying the physiology and pharmacology - of pain transmission and its modulation. Transgenic mouse models will be used to tease out the specific neuronal receptor subtypes involved. Sophisticated behaviour tests will evaluate response to novel treatments. We will create a biobank of human - cancer-infiltrated bone to identify specific patterns of neuronal receptor expression and to validate therapeutic targets in humans. In an extensive training effort covering both specific research skills and transferable skills, the students will - obtain an interdisciplinary, state-of-the-art and innovative training from the participants, several of which have experience from international networks. The students will benefit from secondments with industrial partners and with some of the - foremost pain researchers in Europe. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Denmark - - - BonePain - - - H2020-MSCA-ITN-2014 - - - 642720 - - - - - POLITECHNIKA POZNANSKA - UNIWERSYTET PRZYRODNICZY W POZNANIU* - INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK - UNIWERSYTET IM. ADAMA MICKIEWICZA W POZNANIU - AKADEMIA WYCHOWANIA FIZYCZNEGO IM EUGENIUSZA PIASECKIEGO - UNIWERSYTET EKONOMICZNY W POZNANIU - - - EUR 132 775 - - - Enthusiasm, Passion, Inspiration, Challenge (EPIC) – join us during the Researchers’ Night and see for yourself how by connecting science and passion one can make a difference! - - - EUR 139 825 - - - Poland - Poland - Poland - Poland - Poland - Poland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - "Researchers’ Night again in Poznan! EPICNight! Enthusiasm, Passion, Inspiration, Challenge– join us during the Researchers’ Night and see for yourself how by connecting science and passion one can make a difference! Come and - uncover the secrets of scientists and researchers! Open the doors to your good neighbours – researchers! Measure immeasurable and see invisible! Become a researcher for one night and construct DNA helix, have a ride in 3D helmet, design your own - clothes or learn the secrets of Eco-robots! Come and sing karaoke songs with researchers and at the end dress up like a famous scientist and dance with us cha-cha or jive. Feel like doing some sport? These and many other attractions are waiting for - you to reveal your passion for science and convince you that researchers are just ordinary people with an extraordinary job and various hobbies! - - 2015-12-31, closed project - - - 2014-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.5."> - - - MSCA-NIGHT-2014 - European Researchers' Night (NIGHT) - - - CSA - Coordination and support action - - - Poland - - - EPICNIGHT - - - H2020-MSCA-NIGHT-2014 - - - 633236 - - - - - UNIVERSITAT ROVIRA I VIRGILI - ECOLE POLYTECHNIQUE - NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - SILVACO EUROPE LTD - INFINISCALE SA - ADMOS GMBH ADVANCED MODELING SOLUTIONS - TECHNISCHE HOCHSCHULE MITTELHESSEN - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 742 500 - - - Design Oriented ModellINg for flexible electrOnics - - - EUR 742 500 - - - Spain - France - Netherlands - France - United Kingdom - France - Germany - Germany - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Our project aims to fill the gap between flexible electronic technology and design by developing highly predictive, generic, open-source, design-oriented organic and oxide based TFT compact model libraries, to be integrated in - commercial Electron Design Automation (EDA) environments for full large area low cost circuit design for novel applications. These model libraries will be released together with parameter extraction standard templates to assist in the fast transfer - between initial prototype device measurements to full product design. Such a facility will open the opportunity for wide flexible electronics design - - 2018-11-30, ongoing project - - - 2014-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Spain - - - DOMINO - - - H2020-MSCA-RISE-2014 - - - 645760 - - - - - ACADEMISCH ZIEKENHUIS GRONINGEN - UNIVERSITY OF KENT - INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE - STOCKHOLMS UNIVERSITET - HUMBOLDT-UNIVERSITAET ZU BERLIN - ERNST-MORITZ-ARNDT-UNIVERSITÄT GREIFSWALD - NOVOZYMES A/S - DSM FOOD SPECIALTIES BV - UCB Celltech - - - EUR 3 685 072,68 - - - Engineering of new-generation protein secretion systems - - - EUR 3 685 072,68 - - - Netherlands - United Kingdom - France - Sweden - Germany - Germany - Denmark - Netherlands - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The market for recombinant proteins, including biopharmaceuticals, industrial enzymes and membrane proteins, is estimated to be about 78 billion Euro and rising. A high proportion of the target proteins are produced in - bacteria, where secretion out of the cytoplasm is a favoured strategy. However, current production platforms have severe limitations and cannot handle many secreted enzymes and membrane proteins. There is an overwhelming need for new production - systems that can deliver these products in greater yields, with higher quality and at lower costs. The 'ProteinFactory' ETN will meet these challenges through the provision of a suite of super-secreting strains with unique capabilities. These strains - will be engineered to bypass major production bottlenecks such as secretion stress, and will be capable of secreting an unprecedented range of target molecules. Equally important will be the training of a new generation of researchers, versed in - Systems and Synthetic Biology approaches. The ProteinFactory project will involve extensive collaboration between 6 academic Institutes, who provide world-leading expertise in synthetic biology and protein secretion, and 5 non-academic partners who - include some of the world's premier biotechnology companies. Training will be inter-sectoral from the outset, with every ESR undertaking extensive secondments within the non-academic partners in order to encourage an entrepreneurial mind-set. The - project is furthermore explicitly multi-disciplinary in scope, with two of the five research work packages dominated by theoretical approaches. Based on a responsible innovation approach and with a clear focus on inter-sectoral collaboration, - ProteinFactory will deliver a cohort of superbly-trained scientists, put the industrial and SME partners at the forefront of global competition and reinforce European innovation potentials with growth and job creation. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Netherlands - - - ProteinFactory - - - H2020-MSCA-ITN-2014 - - - 642836 - - - - - UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK - INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - - - EUR 4 698 623,50 - - - Access to European Nanoelectronics Network - - - EUR 4 698 623,75 - - - Ireland - Belgium - France - - - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - - ASCENT will provide access to the world’s most advanced 10 nm and beyond-CMOS nanoelectronics data and test structures in Europe’s leading nanofabrication research institutes. The institutes involved have extensive advanced - semiconductor processing fabrication facilities, flexible nanofabrication facilities, advanced electrical characterization equipment and expertise in atomistic and TCAD modeling. This will be the first time that access to these state-of-the-art - devices and test structures will be available anywhere in the world. The impact of this access, and the resulting advances that will be made, will contribute significantly to competitiveness and growth capacity in the Europe’s nanoelectronics - industry. - - - 2019-04-30, ongoing project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.2."> - - - INFRAIA-1-2014-2015 - Integrating and opening existing national and regional research infrastructures of European interest - - - RIA - Research and Innovation action - - - Ireland - - - ASCENT - - - H2020-INFRAIA-2014-2015 - - - 654384 - - - - - AARHUS UNIVERSITET - INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM - STICHTING KATHOLIEKE UNIVERSITEIT - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - QUANTUMWISE A/S - - - EUR 3 395 178,25 - - - Spintronic-Photonic Integrated Circuit platform for novel Electronics - - - EUR 3 395 178,25 - - - Denmark - Belgium - Netherlands - France - Denmark - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The main objective of SPICE is to realize a novel integration platform that combines photonic, magnetic and electronic components. Its validity will be shown by a conceptually new spintronic-photonic memory chip demonstrator - with 3 orders of magnitude higher write speed and 2 orders of magnitude lower energy consumption than state-of-the-art spintronic memory technologies. This enables, e.g., future petabit-per-second processor-memory bandwidths, required in a decade - from now, and highly energy-efficient exascale datacenters with reduced carbon footprint. Such a versatile memory will result in so-called Universal Memory: one technology for all memory applications ranging from cache to storage. - - 2020-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-1-2014 - FET-Open research projects - - - RIA - Research and Innovation action - - - Denmark - - - SPICE - - - H2020-FETOPEN-2014-2015-RIA - - - 713481 - - - - - INSTYTUT BIOLOGII DOSWIADCZALNEJ IM. M. NENCKIEGO POLSKIEJ AKADEMII NAUK - - - EUR 2 302 080 - - - International Doctoral Programme in Biological Bases of Human Diseases - - - EUR 4 604 160 - - - Poland - - - Research Organisations - - The major aim of Bio4Med (Biology for Medicine) programme is to provide unique, international, inter-disciplinary and inter-sectoral doctoral training for Early Stage Researchers (ESRs) in the domain of biological bases of - human diseases. To achieve this goal it combines 22 leading research groups at the Nencki Institute and their scientific partners from world-class laboratories located in EU Member States, Switzerland, Ukraine, Japan, Canada and US. Research - programme includes basic science PhD-projects focused on molecular basis of neurodegeneration, neurological disorders, cancer and metabolic diseases. All supervising researchers engaged in the Bio4Med are at the international forefront of biomedical - research and have experience in PhD student supervision. Our programme will foster young researchers’ career development and employability by addressing the following objectives: (i) to offer excellent training in modern biology and endow ESRs with - unique scientific knowledge, and experience in cutting-edge experimental techniques; (ii) to enhance research-oriented and transferable skills of ESRs; (iii) to promote scientific mobility via international, inter-disciplinary and inter-sectoral - collaboration. The objectives of Bio4Med will be delivered through activities encompassing practical laboratory training, hands-on workshops, lectures corresponding to the theoretical aspects of doctoral projects, research-oriented generic skills - courses, transferrable skills courses, progress talks and meetings. The training programme itself, focused on medically important issues, will make ESRs highly attractive to commercial enterprises, particularly in biotechnology and pharmaceutical - sectors. Bio4Med programme will increase the regional, national as well as EU competitiveness by providing a new generation of visionary and innovative researchers able to transform basic science into healthcare solutions. - - 2020-04-30, ongoing project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2014-DP - Marie Skłodowska-Curie Co-funding of regional, national and international programmes (COFUND-DP) - - - MSCA-COFUND-DP - Doctoral programmes - - - Poland - - - Bio4Med - - - H2020-MSCA-COFUND-2014 - - - 665735 - - - - - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - - - EUR 149 404 - - - Classical Levitonics: transposing quantum levitons to classical waves for single side band wireless data transmissions - - - EUR 149 404 - - - France - France - - - Research Organisations - Research Organisations - - The project addresses the field of wireless digital communication. This field has constantly grown during the last twenty years with the development of cell phones and WiFi Local Area Network and with the development of - digital TV broadcasting and satellite communications. A second expansion of digital communications has recently started with networks of objects: Bluetooth smart devices are available to consumers and RFID devices are used for object tagging, - security identification and health sensors. Connecting devices will lead in a very near future to the Internet of Things. Digital communications form a huge market of 100 billion of transceivers connecting humans and devices. Any technological - improvement is expected to generate important economic benefits. This is the aim of C-Levitonics. To physically encode binary information, wireless, optical fiber or copper wire data transmissions are based on the modulation of the phase or the - amplitude of an electromagnetic wave, called carrier wave. A new waveform for the phase modulation associated with an elementary symbol (or bit) is proposed. It derives from a direct application to classical physics of the recently discovered - levitons in quantum physics, a by-product of a former ERC AdG MeQuaNO project. The new modulation, called Single Side Band Phase Shift Keying (SSB-PSK), provides attractive spectral properties: single side band (SSB) spectrum (highly desired feature - in optical or radio communications) and reduced frequency bandwidth allowing more users in a frequency range. Totally new (patent pending) SSB-PSK can operate using existing digital communication technology. A convincing demonstrator based on - software radio technology will be delivered. In parallel a market prospective will identify the best markets and the technical specifications adjusted to them. At the end of the C-Levitonics project a start-up will be created providing development, - consulting services and licensed technology transfer. - - 2017-05-31, closed project - - - 2015-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2015 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - France - - - C-Levitonics - - - ERC-2015-PoC - - - 680875 - - - - - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - - - EUR 149 634 - - - Universal Pulses for Parallel Transmission and Magnetic Resonance Imaging - - - EUR 149 634 - - - France - France - - - Research Organisations - Research Organisations - - The parallel transmission technology is a promising technique to counteract the radiofrequency (RF) field inhomogeneity problem in Magnetic Resonance Imaging (MRI) at ultra-high field. It consists of placing around the subject - several RF transmitters that can be controlled independently in amplitude and phase. By using sophisticated algorithms, it is then possible to design the respective waveforms which lead to a uniform excitation. This powerful tool on the other hand - has remained a research instrument mostly due to the calibration and calculation time necessary to exploit the technology in each exam (around 10 minutes), and the required expertise to calculate the waveforms. - - - 2018-02-28, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2015 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - France - - - UniPAT - - - ERC-2015-PoC - - - 700812 - - - - - KINGSTON UNIVERSITY HIGHER EDUCATION CORPORATION - - - EUR 146 591,10 - - - Efficient methods for radiative heat transfer analysis in fires and water sprays for fire suppression - - - EUR 146 591,10 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The annual cost of losses due to fires is estimated at €126bn, equivalent to 1% of European global gross domestic product (GDP). The use of performance-based fire safety engineering which relies on fire modeling is seen as a - good step to reduce fire losses. Thermal radiation is the most dominant mode of heat transfer in fires and its rigorous and efficient modeling is therefore critical for the reliability of fire safety codes employed in fire engineering. The project - aims to improve the current modeling strategies of radiative heat transfer in fires and in fire suppression by water sprays where the interaction between fires and water droplets should be taken into account. Current computational methods used in - fire modeling and fire suppression suffer from the main following drawbacks: (1) They use the optically gray Planck mean radiative properties of the composite medium, which are too crude to describe the real spectral behavior of thermal radiation (2) - The angular dependence of the radiation intensity is usually approximated with too much details without accounting for the real radiation field; (3) The computational mesh taken from the Computational Fluid Dynamics (CFD) part of the general fire - code is too detailed and not appropriate for radiative transfer calculations; (4) the computational requirements for current fire CFD codes are prohibitive and this is an obstacle. - - 2019-02-28, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - RAD-FIRE - - - H2020-MSCA-IF-2016 - - - 749220 - - - - - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - SAFRAN ELECTRONICS & DEFENSE - UNIVERSITY COLLEGE LONDON - TECHNISCHE UNIVERSITAET BERLIN - - - EUR 2 702 397,50 - - - Data Learning on Manifolds and Future Challenges - - - EUR 2 702 397,50 - - - France - Greece - France - United Kingdom - Germany - - - Research Organisations - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - "Future data processing challenges in science will enter the "Big Data" era, involving massive, as well as complex and heterogeneous data. Extracting, with high precision, every bit of information from scientific data requires - overcoming fundamental statistical challenges, which mandate the design of dedicated methods that must be both effective enough to capture the intricacy of real-world datasets and robust to the high complexity of instrumental measurements. Moreover, - future datasets, such as those provided by the space mission Euclid, will involve at least gigascale data, which will make mandatory the development of new, physically relevant, data models and the implementation of effective and computationally - efficient processing tools. The recent emergence of novel data analysis methods in machine learning should foster a new modeling framework, allowing for a better preservation of the intrinsic physical properties of real data that generally live on - intricate spaces, such as signal manifolds. Furthermore, advances in operations research and optimization theory pave the way for effective solutions to overcome the large-scale data processing bottlenecks. In this context, the objective of the - DEDALE project is threefold: i) introduce new models and methods to analyze and restore complex, multivariate, manifold-based signals; ii) exploit the current knowledge in optimization and operations research to build efficient numerical data - processing algorithms in the large-scale settings; and iii) show the reliability of the proposed data modeling and analysis technologies to tackle Scientific Big Data challenges in two different applications: one in cosmology, to map the dark matter - mass map of the universe, and one in remote sensing to increase the capabilities of automatic airborne imaging analysis systems." - - 2018-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-1-2014 - FET-Open research projects - - - RIA - Research and Innovation action - - - France - - - DEDALE - - - H2020-FETOPEN-2014-2015-RIA - - - 665044 - - - - - FUNDACAO D. ANNA SOMMER CHAMPALIMAUD E DR. CARLOS MONTEZ CHAMPALIMAUD - - - EUR 160 635,60 - - - Phenotypic characterization of Liver-derived exosomes populations associated with liver metastasis in pancreatic cancers - - - EUR 160 635,60 - - - Portugal - - - Research Organisations - - Tumors are not isolated entities, but complex systemic networks involving cell-cell communication between transformed and non-transformed cells. The milieu created by tumor-associated cells may either support or halt tumor - progression. Non-tumor cells also play a role at distant sites, preparing future metastatic sites to support engraftment and survival of metastatic cells. In addition to cell-cell contact, cells communicate through secreted factors via a highly - complex system involving characteristics such as ligand concentration, receptor expression and integration of diverse signaling pathways. Of these, extracellular vesicles such as exosomes are emerging as novel cell-cell communication players in - physiological and pathological scenarios. We recently described that exosomes produced by highly metastatic pancreatic cancers (PC) induce Liver Pre-Metastatic Niches (LPMN) supportive of hepatic metastasis. Although we defined how LPMN are induced - by PC-derived exosomes, the specific mechanism of how the LPMN support the formation and progression of liver metastatic lesions is still unknown. In addition, while we have been showing that pre-metastatic niches support metastatic spreading, we - still do not have appropriate means to detect the formation of these niches by non-invasive methods in clinical settings. Thus we propose to: 1)Characterize the composition of liver-derived exosomes populations in physiologic and LPMN-associated - settings by applying state-of-the-art flow cytometry tailored to nanoparticles analysys at a single-exosome level; 2)Test whether liver-derived exosomes interact with metastatic PC cells and play a role in supporting the progression of PC metastatic - lesions in the liver. This project has the potential to offer not only a non-invasive alternative to detect and characterize tumor-associated microenvironments, such as LPMN, but also opportunities for novel therapeutic approaches to target - pro-tumorigenic cell-cell communication. - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Portugal - - - ONCOSYSTEMS - - - H2020-MSCA-IF-2016 - - - 751547 - - - - - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - - - EUR 185 076 - - - Post-translational modifications during floral initiation: molecular dissection of the UFO-dependent LFY activation - - - EUR 185 076 - - - France - - - Research Organisations - - Flowering plants are the most successful plant group on Earth and provide the basis for most human and animal food. The development of flowers is dependent on a gene regulatory network orchestrated by LEAFY (LFY), the master - transcription factor. In Arabidopsis as in other flowering plants, LFY activity is dependent upon its interaction with UFO, a member of the Skp1–Cullin–F-box E3 ubiquitin ligase complex. The goal of this project is to understand why LFY requires - interacting with UFO to build flowers. For this, we will apply state-of-the-art technologies including mass-spectrometry, crystallography, biochemistry and plant developmental genetics to identify and characterize the function of Post-Translational - Modifications (PTM) on LFY or LFY interacting proteins, with special emphasis on ubiquitination. After identifying key residues involved in the LFY-UFO interaction or targeted by PTM, their functional importance will be assayed in planta. This - project should facilitate better understanding of the mechanism of LFY activation. LEAFY and the development of flower will be used here as a model to understand the “activation by degradation” mechanism, still elusive in most organisms and poorly - studied in plants. Moreover, understanding the principles governing LFY activation should provide means to modify at will the architecture of plant inflorescences. This project builds on the current background of the applicant in the field of - Mass-Spectrometry combined with the outstanding expertise at Grenoble and high-throughput facilities in Structural biology and plant developmental genetics. Notably, the applicant will work within one of the top French Research Centers and in a - multidisciplinary environment that will allow the fellow to acquire complementary ‘new knowledge and skills’ in structural biology and developmental genetics. This will re-enforce the fellow’s background and professional maturity for employment - opportunities in both academia and industry sectors. - - 2019-06-07, ongoing project - - - 2017-06-08 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - PFIMDULA - - - H2020-MSCA-IF-2016 - - - 752418 - - - - - KING'S COLLEGE LONDON - - - EUR 195 454,80 - - - Newcomers at the University. Welcome practices and staff involvement in the UK - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - European universities have significantly changed the way of dealing with newcomers in the last thirty years. As a consequence of the explosion of enrolments, educators, professional staff, and authorities have suddenly been - confronted to new categories of students. In addition, the university's governance has experienced rapid changes concerning internationalisation and mobility. The issues that primarily concern researchers and authorities regard the dropout of - first-year students (FYS) and the utility of mobility programmes to reinforce a “European identity”. - - - 2019-05-22, ongoing project - - - 2017-05-23 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - WELCOME-UNIVERSITY - - - H2020-MSCA-IF-2016 - - - 750444 - - - - - NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU - - - EUR 208 400,40 - - - Taming Irregular Computations On Heterogeneous processors - - - EUR 208 400,40 - - - Norway - - - Higher or Secondary Education Establishments - - In the past decade, more and more heterogeneous processors are equipping modern supercomputers. Unfortunately, despite the progress of hardware infrastructure, the utilization of heterogeneous computing is still relatively low - in practice. The utilization mainly suffers from two bottlenecks: distributed memories that bring high cost for software engineering and degraded performance, and lack of heterogeneity-oriented scalable approaches for irregular problems. The - objective of the project TICOH is to address the issue of currently unsatisfactory utilization of heterogeneous computing for irregular problems such as graph and sparse matrix processing. Following a multi-level approach which bridges the domains of - performance measurement, benchmark data analysis, modeling, data structure construction, algorithm design and application integration, TICOH will explore best practices that toward the best performance for irregular computations on the best hardware - selection. Specifically, the main focus of the project will be to (a) identify and understand bottlenecks of current heterogeneous computing, (b) benchmark and model heterogenous processors composed of CPU, GPU and high-bandwidth memories, (c) design - and evaluate new data structures and algorithms for irregular problems aiming for fully use computing and memory resources, and (d) integrate and apply the newly designed approaches for high-level applications. By empirically investigating these - issues, the ultimate goal of the project is to allow a broad range of real-world applications to further benefit from heterogeneous hardware in the new era. Prof. Anne C. Elster will be hosting this action at the HPC-Lab of NTNU. Her research team is - known for its experience with heterogeneous computing, and is one of the main partners in the H2020 CloudLightning project. This environment will guarantee successful bidirectional transfer of knowledge. - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Norway - - - TICOH - - - H2020-MSCA-IF-2016 - - - 752321 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 170 121,60 - - - Dolphinfish living in a warming ocean: How global climate change is reshaping the distribution, physiology and behaviour of marine migratory species and their associated fisheries. - - - EUR 170 121,60 - - - Spain - - - Research Organisations - - Ranges of individual fisheries are shifting in response to ocean warning. These shifts can cause economic disruptions if a fish population becomes less or more productive or moves out of traditional fishing grounds. - Dolphinfish are known to exhibit strong responses to CC through shifts in spawning areas, larval growth, etc. Dolphinfish inhabit tropical and subtropical waters of the world, including Mediterranean, and it supports commercial, artisanal and - recreational fisheries. Balearic Islands, provide a paradigmatic case-study area and fishery scenario for a process-based understanding of how CC may impact migrant species of commercial interest in Europe. Co-tRiP objective is to address ecological - socioeconomic consequences of CC on a migrant pelagic fish species under fishing pressure in NW Med. Specific objectives include: 1) To estimate the effect of environmental variability on extension and localization of spawning area, phenology of - reproduction and growth of dolphinfish; 2) to address how inter-annual variability of spatial distribution, phenology of reproduction and growth of species, and long-term environmental trends can be used in projecting impacts of CC, such as - distribution shifts; 3) to evaluate how projected changes would potentially affect fisheries and anticipate the adjustment of industry. Using a multi-model approach, Co-tRiP will provide more insight into the effect of CC on distribution shift. - Co-tRiP will build probabilistic maps, based on distribution models, for spawning area through merging disperses data from multiple sources. Models will be used to back-calculate environmental conditions for spawning in past and present, and project - how these will change in future. Data will be used to feed a bio-economical model in order to project how phenological changes may impact fishery, and how it may use this information. Further projections on distribution and phenology will be - performed using a suite of ensemble models based on CC scenarios. - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - Co-tRiP - - - H2020-MSCA-IF-2016 - - - 746361 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 173 076 - - - Understanding sexual selection to help controlling an invasive pest species - - - EUR 173 076 - - - France - - - Research Organisations - - Invasive species can have dramatic consequences on the receiving ecosystem and on human activities. At the same time, invasion episodes offer a rare opportunity to observe evolution in action and study adaptation. - Understanding the cornerstone role of sexual selection during adaptation can open an avenue of strategies to fight against pest species. During invasion, novel environmental conditions and rapid changes in the genetic composition of populations are - expected to influence the dynamics of sexual selection. However, neither theory nor data clearly predict whether sexual selection would be reinforced or hampered during an invasive episode. Understanding the subtle consequences of invasion on sexual - selection is crucial, as mating strategies provide tools to fight against pest species. The Sterile Insect Technique (SIT) successfully eliminated several pest species, limiting side-effects on the ecosystem compared to traditional techniques such as - pesticides. In this project, I develop a series of experiments combining artificial selection experiments with large scale phenotyping to investigate the dynamics of sexual selection during invasion and test the potential to exploit mating strategies - to control pest populations in an evolutionary sustainable way. As a model species, I will use Drosophila suzukii, a champion of invasion that colonised several continents and islands in the last decades. Because D. suzukii feeds and oviposits on - close-to-be-marketed fruits, it causes considerable economic losses and the situation requires rapid action. The results of the project will provide both a fundamental understanding of the dynamics of sexual selection during invasion, and essential - information for the development of sustainable, environment friendly methods to fight pest species, in particular D. suzukii. - - 2020-02-29, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - France - - - SexSelec_Invasion - - - H2020-MSCA-IF-2016 - - - 752452 - - - - - SINGULARLOGIC ANONYMI ETAIREIA PLIROFORIAKON SYSTIMATON KAI EFARMOGON PLIROFORIKIS - IQUADRAT INFORMATICA SL - INSTITUT JOZEF STEFAN - BANGOR UNIVERSITY - PANEPISTIMIO THESSALIAS - LJUBLJANSKI URBANISTICNI ZAVOD DD - DIMOTIKI EPICHEIRISI YDREFSIS - APOCHETEFSIS SKIATHOU - IBM Thomas J. Watson Research Center - - - EUR 1 242 000 - - - Holistic Surface Water and Groundwater Management for Sustainable Cities - - - EUR 1 242 000 - - - Greece - Spain - Slovenia - United Kingdom - Greece - Slovenia - Greece - United States - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Urban water management becomes progressively more challenging in the view of population growth and increasing complexity of water management infrastructure. In this line, there is an ever increase demand from the water - providers’ and public authorities’ perspective to critically evaluate the existing water ecosystems at city level in respect to the water supply, waste water treatment, reuse potential and the effect the growing population has on the water ecosystem - and endangered species. To enable effective decision making at the entire city level, both surface water and groundwater should be viewed as part of the overall urban water ecosystem with its spatio-temporal availability, quantity and quality and - competing uses being taken into account. - - - 2021-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Greece - - - Water4Cities - - - H2020-MSCA-RISE-2016 - - - 734409 - - - - - UNIVERSITA DEGLI STUDI DI TRENTO - - - EUR 180 277,20 - - - Study of the role of m6A RNA methylation in the nervous system of Drosophila melanogaster: an in-vivo model to dissect the impact of epitranscriptome reprogramming in physiology and cancer - - - EUR 180 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - The identification of reversible m6A RNA modification strongly points towards the existence of a novel level of complexity of gene expression regulation. Recent studies have suggested that m6A might be involved in several - biological processes and that dysregulation of this modification may contributes to neuro-developmental abnormalities and cancer. The aim of the described research is to clarify the role of m6A RNA modification in the nervous system in physiological - conditions -during brain development - and to discover its contribution to pathological conditions - Glioblastoma. To achieve this goal I propose to use Drosophila melanogaster to study : Aim 1 the impact of perturbing different members of the m6A - machinery on brain morphology, progenitors differentiation and neuronal axon growth and guidance; Aim2 the impact of modulating the levels of m6A RNA modification in a Glioblastoma model and study the effect of this perturbation on tumor growth and - progression. The results obtained will be of fundamental importance for the development of the field of epitranscriptomics by shedding light on the biological outcome of m6A modification in-vivo. In particular, Drosophila might become an efficient - model to screen for novel members of the m6A machinery and to clarify how m6A is read and translated into a biological response. Finally, the data obtained by the analysis of the Glioblastoma model, will strongly contribute to the understanding of - the link between RNA methylation and tumor development and aggressiveness. - - 2019-09-18, ongoing project - - - 2017-09-19 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - EpiMethFly - - - H2020-MSCA-IF-2016 - - - 752621 - - - - - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - - - EUR 150 000 - - - 'Total E-field Reconstruction using a MIchelson TEmporal Scan' for spatio-temporal metrology of ultrashort laser beams - - - EUR 150 000 - - - France - France - - - Research Organisations - Research Organisations - - The technology of femtosecond lasers now makes it possible to reach enormous light intensities with only moderate amounts of energy. These so-called Ultra-High Intensity (UHI) lasers have led to the development of a very - active research field, which studies the interaction of light with matter at these extreme intensities. This field is largely motivated by the prospects of generating compact sources of high-energy particles and short-wavelength light, which are - being foreseen for applications in particle physics, material science, nuclear fusion technology, medicine. - - - 2018-10-31, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - France - - - TERMITES - - - ERC-2016-PoC - - - 727427 - - - - - UNIWERSYTET IM. ADAMA MICKIEWICZA W POZNANIU - - - EUR 134 462,40 - - - Electric field driven propulsion and collective dynamics of homogeneous and patchy colloidal capsules. - - - EUR 134 462,40 - - - Poland - - - Higher or Secondary Education Establishments - - Colloidal capsules are interesting from the point of view of both physics and application. They can be used for controlled material transport and targeted release, and they have shown tremendous potential for fabricating - advanced materials through self-assembly. Recently, such capsules have also been able to propel in carrier fluid by methods including magnetic fields, thermal gradients and bubble propulsion mechanisms. Building on former research by the Experienced - Researcher and the main supervisor, as well as new areas of expertise, this project will develop novel fabrication routes for microcapsules with and without functionalised shells (patchy capsules) and propel them over milimeter distances using - external fields. The main objective of this action is to experimentally demonstrate propulsion of microcapsules via novel methods involving anisotropic electrodeformation and electrorotation. The experimental research will fill the missing gap in the - field of propelling capsules, now mostly presented by computational and theoretical work. - - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Poland - - - PaCDoC - - - H2020-MSCA-IF-2016 - - - 752896 - - - - - UNIVERSITEIT LEIDEN - INSTALLATION EUROPEENNE DE RAYONNEMENT SYNCHROTRON - LEIDEN PROBE MICROSCOPY BV - TECHNISCHE UNIVERSITAET MUENCHEN - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - PANEPISTIMIO PATRON - - - EUR 3 726 942,50 - - - Development of continuous two-dimensional defect-free materials by liquid-metal catalytic routes - - - EUR 3 726 942,50 - - - Netherlands - France - Netherlands - Germany - France - Greece - - - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - - Two-dimensional materials (2DMs) such as graphene, hexagonal boron nitride, silicene and others, are currently amongst the most intensively studied classes of materials that hold great promise for future applications in many - technological areas. However, the main hurdle against practical utilization of 2DMs is the lack of effective mass production techniques to satisfy the growing qualitative and quantitative demands for scientific and technological applications. The - current state-of-the-art synthesis method of 2DMs involves the dissociative adsorption of gas-phase precursors on a solid catalyst. This process is slow by nature, inefficient, and environmentally unfriendly. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-01-2016-2017 - FET-Open research and innovation actions - - - RIA - Research and Innovation action - - - Netherlands - - - LMCat - - - H2020-FETOPEN-1-2016-2017 - - - 736299 - - - - - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - - - EUR 1 500 000 - - - Exploding stars from first principles: MAGnetars as engines of hypernovae and gamma-ray BURSTs - - - EUR 1 500 000 - - - France - France - - - Research Organisations - Research Organisations - - The birth of a neutron star with an extremely strong magnetic field, called a magnetar, has emerged as a promising scenario to power a variety of outstanding explosive events. This includes gamma-ray bursts, among the most - luminous events observed up to high redshift and therefore useful as cosmological probes, but also supernovae with extreme kinetic energies called hypernovae and other classes of super-luminous supernovae. Simple phenomenological models, where the - magnetar rotation period and magnetic field are adjusted, can explain many of these observations but lack a sound theoretical basis. The goal of this proposal is to develop an ab initio description of magnetar powered explosions in order to delineate - the role they play for the production of gamma-ray bursts and super-luminous supernovae. This is urgently needed to interpret the growing diversity of explosions observed with ongoing transient surveys (iPTF, CRTS, Pan-STARRS) and in the perspective - of future programs of observations such as SVOM and LSST. By using state-of-the-art numerical simulations, the following outstanding questions will be addressed: - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - MagBURST - - - ERC-2016-STG - - - 715368 - - - - - TALLINNA TEHNIKAULIKOOL - UNIVERSITE DE LAUSANNE - - - EUR 1 318 500 - - - Institutions for Knowledge Intensive Development: Economic and Regulatory Aspects in South-East Asian Transition Economies - - - EUR 1 318 500 - - - Estonia - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The prioritisation and deployment of knowledge within an economy remains a key success factor for long-term economic development, increased productivity and socio-economic sustainability. The achievement of knowledge-driven - growth is particularly challenging for emerging market economies that are still seeking to catch up to the frontier knowledge economies. The project seeks to understand the causes and consequences of the differences in the evolution of knowledge - intensity of economies, with particular focus on transition countries in South-East Asia. We aim to identify some key micro and macro level institutional incentives for development towards a knowledge economy, and stimuli for capital allocation into - knowledge-based investments. Moreover, we seek to study and outline some key channels for efficient regulation that might contribute to knowledge intensification in a transition economy. The project makes use of frontier empirical research methods, - including advanced stochastic frontier analysis and dynamic panel data estimation techniques. The conceptual underpinnings of the project are at the intersection of industrial organisation theories, new institutional economics, development economics, - and modern concepts in regulatory efficiency and justice. The project will develop lasting excellence oriented cooperation with South-East Asian universities, and contribute to R&D capacity building based on European academic values. Promoting of - the project results through intersectoral knowledge transfer will be an important task. We aim to contribute to social innovation through policy suggestions, and to a paradigm shift regarding the role of institutions in transition processes. The - project is a joint effort of Swiss and Estonian universities’ economics and law researchers with transition studies experience from Eastern Europe, and their fellow researchers from Laos, Vietnam and Cambodia with thorough insight into the - institutional context in their societies. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Estonia - - - IKID - - - H2020-MSCA-RISE-2016 - - - 734712 - - - - - GRAND ACCELERATEUR NATIONAL D'IONS LOURDS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - GSI HELMHOLTZZENTRUM FUER SCHWERIONENFORSCHUNG Gmbh - THE HENRYK NIEWODNICZANSKI INSTITUTE OF NUCLEAR PHYSICS, POLISH ACADEMY OF SCIENCES - NUCLEOPOLIS POLE NORMAND DES SCIENCES NUCLEAIRES ET DE LEURS APPLICATIONS - - - EUR 3 883 390 - - - International Development of gAnil-spirAL2 - - - EUR 3 883 390 - - - France - France - France - Germany - Poland - France - - - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Other - - The objectives of the IDEAAL Project are to explore all possibilities to develop GANIL infrastructure, with its new ESFRI SPIRAL2 facility, in order to ensure its long-term sustainability as one of the premiere European - research institutes for nuclear physics, interdisciplinary sciences and related applications. - - - 2019-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-03-2016-2017 - Individual support to ESFRI and other world-class research infrastructures - - - CSA - Coordination and support action - - - France - - - IDEAAL - - - H2020-INFRADEV-2016-1 - - - 730989 - - - - - FORSCHUNGSZENTRUM JULICH GMBH - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - CINECA CONSORZIO INTERUNIVERSITARIO - BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION - GRAND EQUIPEMENT NATIONAL DE CALCUL INTENSIF - - - EUR 25 967 653,25 - - - Public Procurement of Innovative Solutions for High-Performance Computing - - - EUR 74 193 295 - - - Germany - France - Italy - Spain - France - - - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Other - - In its communication on the “European Cloud Initiative” the European Commission in April 2016 stressed the need for building an European Data Infrastructure including high-end supercomputers, which will around 2022 reach the - exascale performance level. In this proposal, a group of leading European supercomputing centres propose the formation of a buyers group to execute a joint Public Procurement of Innovative Solutions (PPI) in the area of high-performance computing - (HPC). The co-funding by the European Commission (EC) will allow for a significant enhancement of the planned pre-exascale HPC infrastructure from 2018 on. The total investment is planned to be about € 73 million. - - 2021-09-30, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.3."> - - - EINFRA-21-2017 - Platform-driven e-infrastructure innovation - - - PPI - Public Procurement of Innovative solutions - - - Germany - - - PPI4HPC - - - H2020-EINFRA-2016-2 - - - 754271 - - - - - ALMA SISTEMI SAS DI DI IORIO ALESSIO & C - UNIVERSITY OF SOUTHAMPTON - MARS SPACE LTD - UNIVERSITA DEGLI STUDI DI PADOVA - TECHNOLOGY FOR PROPULSION AND INNOVATION SRL - THE RESEARCH COMMITTEE OF THE TECHNICAL UNIVERSITY OF CRETE - - - EUR 792 000 - - - Plasma Antenna Technologies - - - EUR 792 000 - - - Italy - United Kingdom - United Kingdom - Italy - Italy - Greece - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - PATH is intended to promote a collaborative researches focused in the development of high density plasma sources - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Italy - - - PATH - - - H2020-MSCA-RISE-2016 - - - 734629 - - - - - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - - - EUR 137 155 - - - Few-Cycle Electric Field Waveforms for Advanced Science and Technology - - - EUR 137 155 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The aim is the development of a user friendly high power few cycle, phase stable, light source in the 1500-2000 nm wavelength range. This builds on technical feasibility demonstrated during the ASTEX Advanced Grant. To fully - exploit the potential of this light source it is necessary now to optimize the following characteristics: peak power, the ultimate pulse duration, stability and convenience of use. We hope to do this by building on the work carried out in the ASTEX - project, that demonstrated the principle of the generation and application of few cycle waveform stable 1800 nm pulses, by optimising the generation, power and convenience of use to enable many potential applications. It is the aim of this project - therefore to develop this light source as a user friendly, stand-alone, optical device that can be located after a variety of commercial ultrafast OPA (Optical Parametric Amplifier) systems and so deliver few cycle 1500-2000 nm high power pulses - directly to many and varied applications in technology and science. The applications are expected to have industrial/societal impact in Defence, Security, Analytical and Measurement Technology sectors. - - - 2019-02-28, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - FEWFAST - - - ERC-2017-PoC - - - 767112 - - - - - BOGAZICI UNIVERSITESI - - - EUR 157 734 - - - Effects of Structural Change on Income Inequality - - - EUR 157 734 - - - Turkey - - - Higher or Secondary Education Establishments - - This project aims to identify the distributional effects of the structural change phenomenon. It develops a dynamic macroeconomic model that introduces heterogeneities across workers and asset owners into the structural change - models. For this purpose, it will focus on growth models with heterogeneous agents and complete asset markets. With this methodology, we will be able to characterize not only the aggregate patterns of structural change, but also its distributional - consequences. By uncovering the long term factors behind the evolution of income distribution during structural change, the proposed model will be highly relevant to the most recent debates of rising income inequality in developed countries. The - theoretical model will be calibrated to assess and quantify the historical roots of the current distributional picture in U.S. and Europe. In doing so, it will determine the “structural” level of inequality; a level that is due to the intrinsic - forces of structural change. Then any deviations -positive or negative- from this level can be identified as “political”, which would provide a clearer picture of the effects of governmental policies on inequality. This model will be the first in the - literature to integrate structural models with distributional issues and will open up a new research area. Finally, the model will be enriched with fiscal policies such as income taxes and productive government spending in order to draw policy - conclusions regarding the growth-income inequality relationship in Europe, where boosting economic growth while holding the income inequality at a socially acceptable level has been a major concern in recent years. Therefore, the proposed project - will both contribute to advancement of European research and address one of the Societal Challenges targeted by H2020 programs, which is working towards “Inclusive, innovative and reflective societies”. - - 2019-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Turkey - - - STRCHANGEINEQ - - - H2020-MSCA-IF-2016 - - - 753537 - - - - - PANEPISTIMIO PATRON - PANEPISTIMIO PATRON - - - EUR 150 000 - - - Assessing compounds targeting DNA replication licensing complexes as anti-tumor agents - - - EUR 150 000 - - - Greece - Greece - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Cancer is a major clinical, societal and economic burden worldwide and development of novel anti-cancer therapies constitutes a major investment of public and private funds. Despite intense research over decades however, which - has led to a much improved understanding of cancer biology, cancer treatment remains a challenge. This is to a large extent due to the genetic heterogeneity of cancer and the ability of cancer cells to escape treatment by constantly undergoing - further genetic alterations. During our ERC funded work, we have shown that aberrations in the DNA replication licensing pathway may contribute to the genome plasticity of cancer cells, and appear a common feature of cancer cells. They may however - also constitute an Achilles foot, as cancer cells appear more dependent on negative regulators of the licensing system for survival. Cancer cells may therefore be more sensitive than normal cells to compounds targeting this control (inhibition of - untimely licensing). We have identified compounds which target the DNA replication licensing inhibitor Geminin. The proposed PoC study will enable us to: - - 2018-12-31, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Greece - - - DynaCOMP - - - ERC-2016-PoC - - - 755284 - - - - - THE UNIVERSITY OF EXETER - THE UNIVERSITY OF EXETER - - - EUR 2 249 834 - - - Emergent Constraints on Climate-Land feedbacks in the Earth System - - - EUR 2 249 834 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The Land Biosphere is a critical component of the Earth System, linking to climate through multiple feedback processes. Understanding these feedback processes is a huge intellectual challenge. In part because of the pioneering - work of the PI (Cox et al., 2000), many of the climate projections reported in the IPCC 5th Assessment Report (AR5) now include climate-carbon cycle feedbacks. However the latest Earth System Models (ESMs) continue to show a huge range in the - projected responses of the land carbon cycle over the 21st century. This uncertainty threatens to undermine the value of these projections to inform climate policy. This project (ECCLES) is designed to produce significant reductions in the - uncertainties associated with land-climate interactions, using the novel concept of Emergent Constraints - relationships between future projections and observable variations in the current Earth System that are common across the ensemble of ESMs. - Emergent Constraints have many attractive features but chief amongst these is that they can make ensembles of ESMs more than the sum of the parts - allowing the full range of ESM projections to be used collectively, alongside key observations, to - reduce uncertainties in the future climate. The project will deliver: (i) a theoretical foundation for Emergent Constraints; (ii) new datasets on the changing function of the land biosphere; (iii) Emergent Constraints on land-climate interactions - based on observed temporal and spatial variations; (iv) a new generation of scientists expert in land-climate interactions and Emergent Constraints. ECCLES will benefit from the expertise and experience of the PI, which includes training as a - theoretical physicist, an early career developing models of the land biosphere for ESMs, and a current career in a department of mathematics where he is at the forefront of efforts to develop and apply the concept of Emergent Constraints (Cox et al., - 2013, Wenzel et al., 2016). - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - ECCLES - - - ERC-2016-ADG - - - 742472 - - - - - INNOVACIO I RECERCA INDUSTRIAL I SOSTENIBLE SL - - - EUR 170 121,60 - - - Advanced Data Modeling and Analysis Applied to next Generation Industry 4.0 settings and the Internet of Things - - - EUR 170 121,60 - - - Spain - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - DATAMINE4.0 is an IF for Career Development for Natasa Sarafijanovic-Djukic, PhD in Computer/Communication Sciences obtained from EPFL, Switzerland, a researcher in statistical modelling originally from Serbia, whereby she - will work in IRIS, a Spanish R&D and advanced engineering SME. The project will study the modeling and analysis of data coming from complex industrial and organizational applications, in order to identify hidden causistic relationships in order - to calibrate production and organizational control systems. It is highly multidisciplinary combining data science, statistics, artificial intelligence, telecommunications, specific engineering and organizational domains and information technology - processing competences. In line with new paradigms such as Industry 4.0 and the Internet of Things. Although machine learning paradigms have been in existence for several decades, their penetration in the industrial and public organization setting - has been limited. The goal is to build calibration and optimization models using advanced statistical and machine learning methods and other artificial intelligence inspired algorithms, for applications in which existing methods have been - unsatisfactory. This will have a big impact on productivity and repeatability of winning formulas for key industrial applications such as customized production, public sector applications (e.g. optimization of urban mobility), and food processing. - This is in line with findings published by the European Union. The developed data mining solutions will greatly enhance the current performance of the selected applications, allowing them a competitive advantage over current methods. The work will be - done in an applied R&D environment in line with the objective for Dr. Natasa Sarafijanovic-Djukic’s career continuation. An engineering approach will be ideally completed with 7 formal scientific trainings, including two academic secondments, - each of 2 months. - - 2020-01-07, ongoing project - - - 2018-01-08 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-SE - Society and Enterprise panel - - - Spain - - - DATAMINE4.0 - - - H2020-MSCA-IF-2016 - - - 752907 - - - - - ISTITUTO EUROPEO DI ONCOLOGIA SRL - ISTITUTO EUROPEO DI ONCOLOGIA SRL - - - EUR 2 000 000 - - - Dissecting the Function of Multiple Polycomb Group Complexes in Establishing Transcriptional Identity - - - EUR 2 000 000 - - - Italy - Italy - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The activities of the Polycomb group (PcG) of repressive chromatin modifiers are required to maintain correct transcriptional identity during development and differentiation. These activities are altered in a variety of - tumours by gain- or loss-of-function mutations, whose mechanistic aspects still remain unclear. - - 2022-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Italy - - - DissectPcG - - - ERC-2016-COG - - - 725268 - - - - - UNIVERSITY OF KENT - UNIVERSITY OF KENT - UNIVERSITY OF LEEDS - THE JAMES HUTTON INSTITUTE - - - EUR 1 953 715,63 - - - Environmental Spaces and the Feel-Good Factor: Relating Subjective Wellbeing to Biodiversity - - - EUR 1 953 715,63 - - - United Kingdom - United Kingdom - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - We live in a time of profound environmental change. Phenomena such as urbanisation and agricultural intensification have led to ecosystem degradation and species extinctions, and thus a reduction in biodiversity. Yet, while it - is now widely asserted in the research, policy and practice arenas that interacting with nature is fundamental to human wellbeing, there is a paucity of evidence characterising how biodiversity, the living component of nature, plays a role in this - accepted truth. With RELATE, I will pioneer a completely novel approach to investigating this challenging problem, innovating through interdisciplinary (human geography, environmental psychology, economics and ecology) integration and the use of both - qualitative and quantitative methods. As such, RELATE will initiate a step-change in our understanding of how nature underpins human wellbeing. Three objectives will be met: (1) explore how people relate to different biodiversity attributes - (particular morphologies, sounds, smells, textures, behaviours and/or cultural meanings associated with species), positively and negatively, across all classes of cultural ecosystem service and types of human-nature experience (intentional, - incidental, indirect, thereness); (2) quantify variation in how people value, or not, different biodiversity attributes using a range of monetary and non-monetary valuation techniques, including new subjective wellbeing measures; (3) understand how - co-occurrence between biodiversity and people may alter across space/time (both seasonal and inter-decadal), and the impact this may have on human-biodiversity relationships. The crucial trade-offs decision-makers tasked with managing environmental - spaces have to make between multiple biodiversity, individual and societal deliverables cannot be optimised until we understand human-biodiversity relationships specifically. Consequently, RELATE will deliver a timely, rich and holistic - evidence-base, supported by transformative science. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - RELATE - - - ERC-2016-COG - - - 726104 - - - - - CEMM - FORSCHUNGSZENTRUM FUER MOLEKULARE MEDIZIN GMBH - CEMM - FORSCHUNGSZENTRUM FUER MOLEKULARE MEDIZIN GMBH - - - EUR 146 668 - - - Chemical Hematology: breaking resistance of hematological malignancies through personalized drug trials - - - EUR 146 668 - - - Austria - Austria - - - Research Organisations - Research Organisations - - Personalized medicine aspires to provide optimal therapy in real-time during patient treatment, however current methodology falls short to deliver this in a robust manner. With this in mind, we invented a method for the - screening of thousands of drug responses in small samples of an individual’s peripheral blood by automated microscopy and single-cell image analysis. We termed this method pharmacoscopy. In the course of carrying out the i-FIVE ERC grant project - plan, we began screening for novel anti-viral or immune modulating drugs. In the quest to increase the physiological relevance of our screening settings, we investigated the possibility of using peripheral blood cells or bone marrow from individuals. - We have thus far been able to show that the approach allows for the screening of anti-inflammatory properties of compounds, and to score for distinct sub-population specific cell cytotoxicity profiles of clinical anti-neoplastic agents through the - tracking of fluorescent antibodies and probes. Moreover, we have been able to show that the approach empowers the therapeutic decision-making capability of hema-oncologists in a concrete clinical setting using primary myelofibrosis and lymphoma as - test diseases. With funding from this grant, we intend to obtain further clinical data through retrospective trials, and incorporate the results into an information package attractive enough to draw the attention of potential investors. We have - secured the intellectual property rights and have assembled the know-how required to enable commercialization efforts. With the unique image-based single cell analysis of human liquid tissues, we believe that chemos has the potential to develop into - a service that enables and advances personalized medicine and drug discovery for a broad spectrum of hematological disorders. - - 2017-09-30, closed project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Austria - - - chemos - - - ERC-2016-PoC - - - 727416 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - UNIVERSITY OF CAPE TOWN - - - EUR 1 998 885 - - - How a mutualism evolves: learning, coevolution, and their ecosystem consequences in human-honeyguide interactions - - - EUR 1 998 885 - - - United Kingdom - United Kingdom - South Africa - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Species interactions such as mutualism, parasitism and predation underpin much of life’s diversity. We aim to understand the mechanistic role of learnt traits in the origin and maintenance of mutualistic interactions between - species, and to test their evolutionary and ecological consequences. To do so, we shall study a remarkable mutualism: the foraging partnership between an African bird species, the greater honeyguide Indicator indicator, and the human honey-hunters - whom it guides to bees’ nests. Honeyguides know where bees’ nests are located and like to eat beeswax; humans have the ability to subdue the bees and open the nest, thus exposing beeswax for the honeyguides and honey for the humans. This model system - gives us a wonderful opportunity to study mutualisms, because local human and honeyguide populations vary strikingly in whether and how they interact, and because we can readily manipulate these interactions experimentally. We have already - demonstrated that it is fully feasible to carry out observational and experimental work at a study site we have established in cooperation with a honey-hunting community in northern Mozambique. Here, and at a series of comparative field sites we have - identified in south-eastern Africa, we shall ask: is learning involved in maintaining a geographical mosaic of honeyguide adaptation to local human cultures? How does reciprocal communication between humans and honeyguides mediate their interactions? - What are the effects of cultural co-extinctions on each partner and their ecosystems, and how quickly can such cultures be re-ignited following their loss? In so doing we shall test for the first time the hypothesis that reciprocal learning can give - rise to matching cultural traits between interacting species. Understanding the role of such phenotypic plasticity is crucial to explain how and why the outcome of species interactions varies in space and time, and to predict how they will respond to - a rapidly changing world. - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - Honeyguides-Humans - - - ERC-2016-COG - - - 725185 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - - - EUR 2 349 898 - - - Adaptive Actin Architectures - - - EUR 2 349 898 - - - France - France - France - - - Research Organisations - Research Organisations - Research Organisations - - Although we have extensive knowledge of many important processes in cell biology, including information on many of the molecules involved and the physical interactions among them, we still do not understand most of the - dynamical features that are the essence of living systems. This is particularly true for the actin cytoskeleton, a major component of the internal architecture of eukaryotic cells. In living cells, actin networks constantly assemble and disassemble - filaments while maintaining an apparent stable structure, suggesting a perfect balance between the two processes. Such behaviors are called “dynamic steady states”. They confer upon actin networks a high degree of plasticity allowing them to adapt in - response to external changes and enable cells to adjust to their environments. Despite their fundamental importance in the regulation of cell physiology, the basic mechanisms that control the coordinated dynamics of co-existing actin networks are - poorly understood. In the AAA project, first, we will characterize the parameters that allow the coupling among co-existing actin networks at steady state. In vitro reconstituted systems will be used to control the actin nucleation patterns, the - closed volume of the reaction chamber and the physical interaction of the networks. We hope to unravel the mechanism allowing the global coherence of a dynamic actin cytoskeleton. Second, we will use our unique capacity to perform dynamic - micropatterning, to add or remove actin nucleation sites in real time, in order to investigate the ability of dynamic networks to adapt to changes and the role of coupled network dynamics in this emergent property. In this part, in vitro experiments - will be complemented by the analysis of actin network remodeling in living cells. In the end, our project will provide a comprehensive understanding of how the adaptive response of the cytoskeleton derives from the complex interplay between its - biochemical, structural and mechanical properties. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - France - - - AAA - - - ERC-2016-ADG - - - 741773 - - - - - UNIVERSITE DE BORDEAUX - - - EUR 264 668,40 - - - A Wearable Sensor for Hormones Based on a Native Microbial Sensing - - - EUR 264 668,40 - - - France - - - Higher or Secondary Education Establishments - - Connected devices that monitor human biology in real-time represent the next frontier in biosensors. Monitoring hormones is of significant interest as hormones play critical roles in multiple physiological processes including - stress adaptation, blood pressure control, reproductive rhythms, and body odor. However, the real-time monitoring of hormones is challenging from a biology, chemistry, and engineering perspective, insulin detection being the one notable success. This - project proposes to design a novel wearable device to sense estradiol (through sweat), a hormone responsible for fertility issues and mood disorders in women. This project is highly innovative and ambitious since it combines microbial genetics and - protein identification, new polymer and nanoparticles compositions, and a novel sensor design. The wearable device (i.e., bracelet) will contain an optical-to-electrical interface for recording the fluorescence output of a biosensor, based on - estradiol sensitive transcription factor isolated from a microbial organism. The biosensor is composed of biopolymers (dendrimers and polypeptides nanoparticles) functionalized with fluorescent molecular beacons (MB) and a hormone-sensitive - transcription factor. Without the hormone, the two fluorescent entities of the MB are linked by the protein and no signal is emitted because of fluorescence resonance energy transfer (FRET), while in the presence of estradiol, the MB separate and a - fluorescent signal is emitted. The project will be conducted in two international prestigious laboratories in France and in the USA to give to the applicant the best interdisciplinary scientific environment, and ensure the ultimate success of this - project. The applicant will be the main spokesperson and lead investigator of the project. This international exposure and this fellowship will provide the applicant a unique and multidisciplinary profile, while facilitating her future academic - career as a researcher in France. - - 2020-03-14, ongoing project - - - 2017-03-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - France - - - SENSHOR - - - H2020-MSCA-IF-2016 - - - 749973 - - - - - WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER - ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA - PHILIPPS UNIVERSITAET MARBURG - CARL ZEISS VISION INTERNATIONAL GMBH - - - EUR 891 000 - - - PLAsticiTY of Perceptual space Under Sensorimotor interactions - - - EUR 1 066 500 - - - Germany - Italy - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Space is the foundational characteristic of visual perception and we generally perceive it as continuous and uniform. Behavioural measurements and the properties of our sensory systems however, demonstrate that this is an - illusory situation and our percept is constructed by the brain. One example is our lack of awareness of the blind spot that exists in each eye. Space is non-uniformly represented in the visual brain and this representation is dynamically influenced - by motor behaviour, in particular by eye movements. The PLATYPUS consortium will investigate the dynamic nature of spatial sensation and perception, focussing on the continuous mutual interaction of motor behaviour and perception. Our research - objectives integrate human behavioural and cutting edge non-human primate electrophysiological research techniques and focus on translation of basic into applied research. Focussing on the adaptive nature of vision and action, strategies to perturb - and probe perceptual space and geometry will allow measurement of spatial and geometrical perception in humans and the representation of such in non-human primates. This research will extend to applications for people wearing progressive lenses which - distort action and space perception, patients with a blind area in their visual field and for virtual reality technology development. PLATYPUS researchers will grow existing and establish new collaborative teams, sharing research techniques, - knowledge and mentoring between established and with upcoming researchers in academia and industry. Individuals will benefit from intense scientific and career development training while institutions will benefit from the exchange of state-of-the-art - techniques. The ultimate outcome will be increased understanding of the continuously updating neural construction of space and the production of assistive technologies for people needing corrective lenses, with ocular or visual discontinuity and for - the growing virtual reality industry. - - 2021-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Germany - - - PLATYPUS - - - H2020-MSCA-RISE-2016 - - - 734227 - - - - - INSTYTUT BIOLOGII DOSWIADCZALNEJ IM. M. NENCKIEGO POLSKIEJ AKADEMII NAUK - INSTYTUT BIOLOGII DOSWIADCZALNEJ IM. M. NENCKIEGO POLSKIEJ AKADEMII NAUK - - - EUR 1 312 500 - - - Functional connectomics of the amygdala in social interactions of different valence - - - EUR 1 312 500 - - - Poland - Poland - - - Research Organisations - Research Organisations - - Understanding how brain controls social interactions is one of the central goals of neuroscience. Whereas social interactions and their effects on the emotional state of an individual are relatively well described at the - behavioral level, much less is known about neural mechanisms involved in these very complex phenomena, especially in the amygdala, a key structure processing emotions in the brain. - - 2021-11-30, ongoing project - - - 2016-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Poland - - - CoSI - - - ERC-2016-STG - - - 715148 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - UNIVERSITE PARIS DIDEROT - PARIS 7 - NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - RIJKSUNIVERSITEIT GRONINGEN - Heinrich-Pette-Institute, Leibniz-Institut fuer experimentelle Virologie - SERVICIO MADRILENO DE SALUD - FASMATECH EPISTIMONIKI KAI TECHNOLOGIKI ANONYMI ETAIREIA - - - EUR 7 148 586,25 - - - Optomechanics for Virology - - - EUR 7 148 586,25 - - - Spain - France - Netherlands - France - Netherlands - Germany - Spain - Greece - - - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Viral infections diagnosis demands novel, cheaper and rapid technologies to overcome present constraints. Current gold standard for diagnosis of viral infections is based on pathogen-targeted nucleic acid identification; thus, - it cannot discern infectious stages from latent ones and it demands time consuming adjustments when mutations occur or new emerging viruses are to be included in the diagnostic protocols. Lately, optomechanics has served to fundamental advancements - in physics, from gravitational wave detection to the study of mechanical quantum ground states but it has not yet delivered its full applicability potential. - - - 2021-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.2."> - - - FETPROACT-01-2016 - FET Proactive: emerging themes and communities - - - RIA - Research and Innovation action - - - Spain - - - VIRUSCAN - - - FETPROACT-2016 - - - 731868 - - - - - GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER - NEDERLANDSE ORGANISATIE VOOR WETENSCHAPPELIJK ONDERZOEK - BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION - ETHNIKO DIKTYO EREVNAS TECHNOLOGIAS AE - INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK - INSTITUTE OF INFORMATION AND COMMUNICATION TECHNOLOGIES - GENIAS BENELUX BV - STICHTING SURF - URANUS COMPUTING LTD - - - EUR 989 537,50 - - - e-Infrastructure Reflection Group Support Programme 5 - - - EUR 989 537,50 - - - Germany - Netherlands - Spain - Greece - Poland - Bulgaria - Netherlands - Netherlands - United Kingdom - - - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Project Summary - - 2018-11-30, ongoing project - - - 2016-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.3.1., H2020-EU.1.4.1.3., H2020-EU.1.4.3.2."> - - - INFRASUPP-03-2016 - Support to policies and international cooperation for e-infrastructures - - - CSA - Coordination and support action - - - Germany - - - e-IRGSP5 - - - H2020-INFRASUPP-2016-1 - - - 730954 - - - - - UNIVERSITY OF SOUTHAMPTON - - - EUR 195 454,80 - - - Ocean Interaction with Antarctic Ice Shelves - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The primary goal OceanIS is to constrain the contribution of changes in Southern Ocean circulation to the recent acceleration in Antarctic Ice Sheet mass loss. Improving our knowledge of ice shelf–ocean interactions is a - critical step toward reducing uncertainty in future sea level rise projections. Ice shelves are coastal areas of floating ice that extend from an ice sheet out over the ocean, and their destabilization can trigger rapid ice discharge. It is now - evident that ocean–driven basal melt is the major cause of ice loss from Antarctica’s fringing ice shelves. However much of the fundamental dynamics of how the ocean delivers heat to the ice shelves remains unresolved. Progress in this area requires - bringing together the fields of ice shelf–ocean interactions and large–scale Southern Ocean oceanography. The Southern Ocean overturning entails the upwelling of Circumpolar Deep Water (CDW) offshore Antarctica. The Antarctic Circumpolar Current has - shifted poleward, the impact of which, e.g. over the upwelling of CDW, remains unknown. Since CDW is linked to the highest ice shelf thinning rates yet observed, the variability of the CDW properties and its interaction with the ice shelves is the - focus of this proposal. To do this, OceanIS integrates, for the first time, several unique data sets, which extend from the deep ocean to the sub–ice shelf environment. These include data from the Argo network, instrumented seals, and measurements - from the only decadal–scale record of ocean properties beneath an Antarctic ice shelf, the Amery ice shelf. OceanIS will help to test which of the suite of current climate models shows ice–ocean interaction processes and CDW variability that are most - in line with reality. Given that the forcings driving Southern Ocean changes are expected to continue in the future, results of OceanIS will be a major step toward reducing the uncertainty that surrounds the future stability of the Antarctic Ice - Sheet and sea level rise projections. - - 2018-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - OceanIS - - - H2020-MSCA-IF-2014 - - - 661015 - - - - - POLITECHNIKA POZNANSKA - UNIWERSYTET PRZYRODNICZY W POZNANIU* - INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK - UNIWERSYTET IM. ADAMA MICKIEWICZA W POZNANIU - AKADEMIA WYCHOWANIA FIZYCZNEGO IM EUGENIUSZA PIASECKIEGO - UNIWERSYTET EKONOMICZNY W POZNANIU - - - EUR 133 347,50 - - - Wielkopolska Researchers’ Night welcomes - Let the experience of the Night last every day! - - - EUR 140 347,50 - - - Poland - Poland - Poland - Poland - Poland - Poland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - "Researchers’ Night again in Poznan! EVERYDAYNIGHT! Wielkopolska Researchers’ Night welcomes - Let the experience of the Night last every day! Come and see how research influences your every-day life! Reveal the - interdisciplinary nature of science and learn how different scientific fields complement each other, making our life better. - - 2017-11-30, closed project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.5."> - - - MSCA-NIGHT-2016 - European Researchers' Night - - - CSA - Coordination and support action - - - Poland - - - EVERYDAYNIGHT - - - H2020-MSCA-NIGHT-2016 - - - 722937 - - - - - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - - - EUR 185 076 - - - Neuron/mast cell interactions in skin diseases - - - EUR 185 076 - - - France - - - Research Organisations - - Atopic dermatitis (AD) is a chronic skin inflammatory disease affecting 10-20% of children worldwide. The etiology of AD is incompletely understood, but many elements (e.g., genetic, environmental or immune) are thought to - contribute to the pathogenesis. The skin is specifically enriched in mast cells (MCs) and innervated by a network of abundant sensory neurons. New findings suggest that nociceptive sensory neurons (nociceptors) might regulate the development of - immune responses. Skin MCs also express a transcriptional signature of genes encoding neuropeptide receptors (e.g., Mrgprb2: the receptor for the substance P [SP]), through which MCs might uniquely interact with nociceptors. Based on solid - preliminary data, the central hypothesis of this project is that SP-producing nociceptor/Mrgprb2+ MC interactions play a critical role in AD pathogenesis. Using a relevant mouse model of AD and innovative imaging approaches, we now aim to elucidate - [1] which subset(s) of nociceptor is involved in AD, [2] how SP+ nociceptor/Mrgprb2+ MC interact in our model and in skin lesions from patients diagnosed with AD and [3] how such interactions might favor skin barrier dysfunction. This project - promises to provide new insights into skin neuro-immune interactions and may lead to the discovery of new therapeutic targets to treat AD pathology. - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - France - - - NEMESIS - - - H2020-MSCA-IF-2016 - - - 749629 - - - - - WEIZMANN INSTITUTE OF SCIENCE - WEIZMANN INSTITUTE OF SCIENCE - - - EUR 150 000 - - - MRI diagnosis using a single-shot imaging technique with unprecedented robustness to field inhomogeneities - - - EUR 150 000 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project seeks to exploit cross-term spatiotemporal encoding (xSPEN), a single-shot MRI modality that we introduced last year as part of our efforts to develop new ultrafast techniques in nuclear magnetic resonance. - Besides delivering single-shot images in tens of milliseconds, xSPEN exhibits an unprecedented resilience to field inhomogeneities enabling it to access regions that have so far never been scanned by single-scan MRI. Over the last year we have - confirmed this and further developed these single-shot measurements, combining it with sequences and algorithms enabling their use in kinetic and diffusivity studies. This PoC proposes to employ these new methods to tackle three problems that pose - open challenges in diagnostic radiology, due to their involvement of tissue-metal and tissue-air interfaces subject to strong susceptibility distortions. These include (i) accessing physiological information in the proximity of metal implants; (ii) - diagnosing cholesteatomas, a middle-ear growth of chronic recurrence with characteristic diffusion parameters; and (iii) examining and diagnosing optic nerve neurofibromatosis tumours by diffusion and by dynamic contrast enhanced MRI. By enabling - non-invasive, mostly diffusion-based characterisations of these challenging radiological problems, xSPEN will provide hitherto unavailable opportunities to perform repetitive, differential diagnoses of diseases whose permanent solution demands - invasive radiation and/or surgery procedures. This can in turn free patients from what could be unnecessary, highly invasive and dangerous operations, preserving a normal lifestyle, and alleviating associated healthcare costs. Furthermore, as despite - its uniqueness xSPEN is compatible with thousands of contemporary clinical MRI machines, validating its diagnostic use on a suitable cohort of volunteers and patients should open a world-wide market of radiological imaging applications, with a life - time of decades. - - 2018-12-31, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Israel - - - X-Imaging - - - ERC-2016-PoC - - - 751106 - - - - - UNIVERSITEIT UTRECHT - ACADEMISCH ZIEKENHUIS LEIDEN - UNIVERSITAETSKLINIKUM HEIDELBERG - CARDIFF UNIVERSITY - UNIVERSITE D'AIX MARSEILLE - KATHOLIEKE UNIVERSITEIT LEUVEN - ARATANA THERAPEUTICS NV - AICURIS GMBH & CO. KG - COMPLIX NV - UNIVERSITAT WIEN - VIROVET - COMPLIX LUXEMBOURG SA - - - EUR 3 849 086,91 - - - European Training Network on Antiviral Drug Development - - - EUR 3 849 086,91 - - - Netherlands - Netherlands - Germany - United Kingdom - France - Belgium - Belgium - Germany - Belgium - Austria - Belgium - Luxembourg - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Viral infections are a major cause of disease, mortality and economic losses worldwide. Antiviral therapy is an essential instrument to control virus infections. At present, however, licensed antiviral drugs have been - developed only against a limited number of viruses (e.g. HIV, HCV, influenza, herpesviruses). There is a clear and unmet need for antiviral drugs to treat infections with other important human pathogens. - - 2019-02-28, ongoing project | - - - 2015-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Netherlands - - - ANTIVIRALS - - - H2020-MSCA-ITN-2014 - - - 642434 - - - - - WIRTSCHAFTSUNIVERSITAT WIEN - WIRTSCHAFTSUNIVERSITAT WIEN - - - EUR 1 999 908,75 - - - Spatially explicit material footprints: fine-scale assessment of Europe’s global environmental and social impacts - - - EUR 1 999 908,75 - - - Austria - Austria - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In the era of globalisation, supply chains are increasingly organised on the international level, thus disconnecting final consumption from the location of material extraction and related environmental and social impacts. - Reducing these global impacts – or footprints – of European consumption is a major societal and scientific challenge. Methods to assess teleconnections between distant places of raw material extraction and consumption along global supply chains have - improved significantly, with multi-regional input-output (MRIO) analysis being the most prominent method applied. However, the limited spatial resolution of MRIO models distorts footprint calculations, as specific properties of raw materials as well - as impacts of extraction can vary significantly within production countries. I therefore propose a new method for the calculation of fine-scale material consumption footprints. It will encompass (1) a spatial assessment of global material extraction - on a high-resolution grid and (2) a detailed physical model that tracks raw materials from the location of extraction via international transport facilities to processing industries in importing countries. Integrating this very detailed spatial - information with a MRIO model will enable the first fine-scale assessment of European countries’ material footprints, overcoming prevailing aggregation errors in footprint indicators. Furthermore, I will investigate environmental and social impacts - related to material footprints through linking the spatially explicit multi-regional material flow model with datasets on impacts related to raw material extraction, such as increasing water scarcity, deforestation and mining conflicts. This project - will not only lift the accuracy of footprint models to a new level, but will also open up a range of options for sustainability assessments of specific commodity flows. Building on this knowledge, targeted policy instruments for sustainable product - supply chains can be designed. - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Austria - - - FINEPRINT - - - ERC-2016-COG - - - 725525 - - - - - STICHTING KATHOLIEKE UNIVERSITEIT - - - EUR 260 929,80 - - - Ideas and Legitimating Discourse in EU and US Agricultural Policy-Making and their Implications for Transatlantic Trade Relations - - - EUR 260 929,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - This project comparatively investigates divergence and convergence in agricultural policy ideas and policies in the EU and the US and their interaction with multilateral and transatlantic trade negotiations. Applying an - innovative Discursive Institutionalist approach, it uncovers whether and how ideas and discourse affect processes of policy transformation. It thus contributes to an ‘ideational turn’ in the field of Agricultural Policy Studies which is currently - dominated by rationalist interest-based explanations. The outcomes of this research will not only explain the dynamics of agricultural policy change and their effect on past trade negotiations, it will also provide policy makers with insights in the - opportunities and limits to develop agricultural policies that are both domestically acceptable and conducive to ongoing transatlantic and international trade negotiations (e.g. TTIP and WTO). This is highly significant considering the important role - of agricultural trade policies in tackling the pressing food and environmental challenges of today and tomorrow. - - 2019-07-31, ongoing project - - - 2016-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Netherlands - - - AGRIDEASCOURSE.TRADE - - - H2020-MSCA-IF-2014 - - - 659838 - - - - - ACADEMISCH ZIEKENHUIS LEIDEN - ACADEMISCH ZIEKENHUIS LEIDEN - - - EUR 2 000 000 - - - Oogenesis spotlighted: making mature human oocytes - - - EUR 2 000 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Women who survive childhood cancer often fail to conceive because their eggs are damaged by (gonadotoxic) chemotherapy. A major breakthrough has been the possibility to cryopreserve cortical strips of their ovarian tissue for - autologous transplantation later in life. This has led to over 40 successful pregnancies worldwide, the latest in the Netherlands. However, the risk of reintroducing cancer cells with the ovarian graft in patients with previous hematopoietic - malignancies is too great and alternatives are needed. - - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - OVO-GROWTH - - - ERC-2016-COG - - - 725722 - - - - - Eidgenössische Technische Hochschule Zürich - Eidgenössische Technische Hochschule Zürich - - - EUR 2 499 887 - - - Cybergenetics: Theory and Design Tools for Biomolecular Control Systems - - - EUR 2 499 887 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - We propose to develop a new theory and design tools for the estimation and real-time control of living cells. The control systems designed using these tools will precisely and robustly steer the dynamic behavior of living - cells in real time to achieve desired objectives. Cells would be controlled either collectively at the population level, or individually as single cells. The control systems achieving this regulation will be realized either on a digital computer that - is interfaced with living cells, or using de novo genetic circuits that are introduced into the cells where they are designed to function as molecular control systems. Our methods will explicitly confront the numerous challenges brought about by the - special environment of the cell including nonlinearity, stochasticity, cell-to-cell variability, metabolic burden, etc. The theory and methods developed in this project will thus enable the systematic, rational, and effective feedback control of - living cells at the gene level, and will lay the foundation for a new corresponding body of knowledge which we call ``Cybergenetics''. It will also open new research directions in the areas of control theory and estimation. - - 2022-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Switzerland - - - CyberGenetics - - - ERC-2016-ADG - - - 743269 - - - - - UNIVERSIDAD POMPEU FABRA - UNIVERSIDAD POMPEU FABRA - FUNDACION CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III - - - EUR 2 499 949 - - - Tissue regeneration and aging: the decisive quiescent stem-cell state - - - EUR 2 499 949 - - - Spain - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - The basic mechanisms of stem cell malfunction during aging are poorly understood even though they underlie the regenerative decline of most organs and tissues as we age. Based on our recent contributions (Nature 2014, Nature - 2016), the fields of tissue regeneration and aging converge on the key role of the quiescent state, the preferred state of stem cells in low turnover tissues such as skeletal muscle. Our unifying hypothesis is that stem-cell quiescence maintenance, - which requires active proteostasis (protein homeostasis), lies at the basis of stemness, and that its substitution by a senescence state in aging impairs regeneration. How these variables connect to drive stem cell aging is not known. Crucial - experimental systems in this proposal are sensitive reporter mice for proteostasis, senescence and quiescence/fate in aging muscle stem cells. The project is divided as follows: Objective 1. Proteostasis and stem cell quiescence maintenance: tracing - proteostasis in quiescent stem cells from autophagy and chaperone-mediated autophagy (CMA) reporter mice during aging / impact of autophagy/CMA loss on quiescence and regeneration / molecular regulators of proteostasis. Objective 2. Proteostasis and - quiescent stem cell heterogeneity and fate: asymmetric segregation of proteotoxic waste as an instructor of stem cell heterogeneity and regenerative fate. Objective 3. The quiescence-to-senescence-switch in aging muscle stem cells: tracing and - isolating senescent stem cells in senescence-cell reporter mice during aging / impact of senescent cell ablation on regenerating aged muscle. Objective 4. Circadian regulation in the quiescent stem-cell state: impact of aging on circadian rhythms and - consequences for quiescence maintenance and regeneration. We expect that completion of these objectives will provide new fundamental knowledge on stem-cell biology, regeneration and aging. - - 2022-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Spain - - - STEM-AGING - - - ERC-2016-ADG - - - 741966 - - - - - IBM RESEARCH GMBH - Eidgenössische Technische Hochschule Zürich - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - UNIVERSITA DEGLI STUDI DI PERUGIA - ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA - CINECA CONSORZIO INTERUNIVERSITARIO - UNIVERSITAT JAUME I DE CASTELLON - THE QUEEN'S UNIVERSITY OF BELFAST - GREENWAVES TECHNOLOGIES - TECHNISCHE UNIVERSITAET KAISERSLAUTERN - - - EUR 5 990 510 - - - Open transPREcision COMPuting - - - EUR 5 990 510 - - - Switzerland - Switzerland - France - Italy - Italy - Italy - Spain - United Kingdom - France - Germany - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - Guaranteed numerical precision of each elementary step in a complex computation has been the mainstay of traditional computing systems for many years. This era, fueled by Moore's law and the constant exponential improvement in - computing efficiency, is at its twilight: from tiny nodes of the Internet-of-Things, to large HPC computing centers, sub-picoJoule/operation energy efficiency is essential for practical realizations. To overcome the “power wall”, a shift from - traditional computing paradigms is now mandatory. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.2."> - - - FETPROACT-01-2016 - FET Proactive: emerging themes and communities - - - RIA - Research and Innovation action - - - Switzerland - - - OPRECOMP - - - FETPROACT-2016 - - - 732631 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - ERNST-MORITZ-ARNDT-UNIVERSITÄT GREIFSWALD - FAKULTNI NEMOCNICE U SV. ANNY V BRNE - WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER - ENANTIS S.R.O - RIJKSUNIVERSITEIT GRONINGEN - BEN-GURION UNIVERSITY OF THE NEGEV - MEDIMMUNE LIMITED - JOHNSON MATTHEY PLC - UNIVERSITE CATHOLIQUE DE LOUVAIN - - - EUR 3 827 031,48 - - - Directed Protein Evolution for Synthetic Biology and Biocatalysis - - - EUR 3 827 031,48 - - - United Kingdom - Germany - Czech Republic - Germany - Czech Republic - Netherlands - Israel - United Kingdom - United Kingdom - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - ES-Cat will use directed evolution as a tool to reproduce Nature's remarkable ability to generate molecular machines - in particular enzymes – that perform at levels near perfection. Instead of seeing rational and - combinatorial approaches as alternatives, we combine them in this network to achieve a ‘smarter’ and more efficient exploration of protein sequence space. By harnessing the forces of Darwinian evolution and design in the laboratory we want to (i) - screen large and diverse libraries for proteins with improved and useful functions, (ii) optimize existing proteins for applications in medicine or biotechnology and (iii) provide a better understanding of how existing enzymes evolved and how enzyme - mechanisms can be manipulated. This Network brings together leading academic and industrial groups with diverse and complementary skills. The range of methodologies represented in ES-Cat allows an integrated approach combining in silico structural - and sequence analysis with experimental high-throughput screening selection methods (phage-, ribozyme and SNAP display, robotic liquid handling, lab-on-a-chip/microfluidics) with subsequent systematic kinetic and biophysical analysis. This - integration of methods and disciplines will improve the likelihood of success of directed evolution campaigns, shorten biocatalyst development times, and make protein engineering applicable to a wider range of industrial targets. It will also train - the next generation of creative researchers ready to fill roles in tailoring enzymes and other proteins for industrial application in synthetic biology efforts to move towards a bio-based economy, rivaling advances that are being made in the US and - allowing the EU economy to harvest its evident socio-economic benefits. - - 2021-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - ES-Cat - - - H2020-MSCA-ITN-2016 - - - 722610 - - - - - COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES - CONSIGLIO NAZIONALE DELLE RICERCHE - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - "NATIONAL CENTER FOR SCIENTIFIC RESEARCH ""DEMOKRITOS""" - SOLVIONIC - C-TECH INNOVATION LIMITED - CENTRO RICERCHE FIAT SCPA - GEMMATE TECHNOLOGIES SRL - HAUTE ECOLE SPECIALISEE DE SUISSE OCCIDENTALE - POLITECHNIKA GDANSKA - - - EUR 4 999 777,50 - - - MAGnetic nanoparticle based liquid ENergy materials for Thermoelectric device Applications - - - EUR 4 999 778,75 - - - France - Italy - France - Greece - France - United Kingdom - Italy - Italy - Switzerland - Poland - - - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - MAGENTA proposes a brand new technological path in thermoelectric materials research for waste-heat recovery applications. The originality of the project is based on the newly discovered thermal-to-electric energy conversion - capacity of ionic-liquids and ferrofluids; i.e., colloidal dispersions of magnetic nanoparticles in ionic liquids (IL-FFs). It is an inter-disciplinary and cross-sector R&D project combining concepts and techniques from physics, chemistry and - electrochemistry with an active participation from 3 SME and 1 industrial partners implicated in the materials supply-chain, the device design/performance and the market-uptake assessment. Both experimental and theoretical approaches will be employed - to build foundational knowledge on novel magneto-thermoelectric phenomena in ferrofluids. Computational simulations will allow ‘bottom-up’ construction of IL-FFs with optimal conditions for harvesting energy. The end-products of MAGENTA, application - specific magneto-thermoelectric materials and devices, will provide innovation leadership to European companies in waste-heat recovery industries. The lead-user industries targeted by MAGENTA are automobile and microelectronic sectors, but - demonstration-type thermoelectric generators will also be produced for public outreach actions on waste-heat recovery technologies. Through its foundational, interdisciplinary and cross-sector research & innovation actions, the consortium will - become a “seed community” for building an innovation ecosystem around the novel magneto-thermoelectric technology, presenting long-term impacts on future renewal energy science and technology from which the society as a whole can benefit. Withal, - MAGENTA offers breakthrough thermoelectric materials that are versatile, cost-effective and non-toxic to assist the economically and environmentally sustainable energy transition in Europe. - - 2020-12-31, ongoing project | - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.2."> - - - FETPROACT-01-2016 - FET Proactive: emerging themes and communities - - - RIA - Research and Innovation action - - - France - - - MAGENTA - - - FETPROACT-2016 - - - 731976 - - - - - FUNDACION PRIVADA INSTITUTO DE SALUD GLOBAL BARCELONA - - - EUR 170 121,60 - - - NeuroCOGNitive impact of Air pollution exposures in Childhood: Assessment of air pollution effects on the development of cognition and behaviour in children - - - EUR 170 121,60 - - - Spain - - - Research Organisations - - Neurological disorders such as Autism Spectral Disorders (ASD) in children are lifelong conditions for which there is no cure,treatment options are very limited AND create huge burdens on children, families and society. - Potential long-term consequences of poor cognitive performance and presence of autistic traits are poor social development, low educational achievement, diminished economic productivity and unemployment, mental health issues, and increased risk of - antisocial behaviour. In the case of ASD, a lifelong disorder, there is no cure and limited treatment options are available. Therefore, it is essential to identify modifiable risk factors to prevent their onset and prevalence. Air pollution is - postulated as a risk factor since it is believed to cause neuroinflammation, oxidative stress and neurodegenerative pathology. Traffic noise shows inconclusive associations with cognitive performance. The experience in cognitive and neurobehavioral - development epidemiologic analysis and wide-scale modelling at the host institution, with different modelling approaches and existing models available for UK and London at the partner's institutions, and the experience of exposure assessment methods - of the fellow dovetail nicely to accomplish the goal of the COGNAC project. This is to explore the associations between air pollution and noise with cognitive performance and the presence of autistic traits in children using a large children cohort. - The innovative aspects of this proposal are combining multi-pollutant and noise exposure, using very detailed maps of these environmental stressors and assessing effects at critical windows of exposure. The scientific impact of this fellowship - results from the identification of the effect of air pollution and noise in cognitive development and the presence of autistic traits in children. The skills acquired in this fellowship will be decisive fo establishing me in one of the leaders in - environmental health applied to neurocognition. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - COGNAC - - - H2020-MSCA-IF-2016 - - - 750531 - - - - - KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW - - - EUR 242 929,80 - - - Causal study of the role of feedback in the perceptual inference of figure location in the primate visual cortex using targeted optogenetics - - - EUR 242 929,80 - - - Netherlands - - - Research Organisations - - The perception of complex visual scenes requires active processing by the brain. The visual cortex is hierarchically organized in several areas which are linked by connections projecting from lower to higher areas - (feedforward) and connections projecting from higher to lower areas (feedback). More complicated processing occurs in higher areas such as V4, where neurons encode which side of a border belongs to a figure. Feedback connections are large in number - but their function is poorly understood. An important role for feedback has been proposed in probabilistic inference, whereby cortical areas “infer” the reality in the external world based on the sensory information they receive from lower areas, - combined with prior hypotheses projected down from higher areas. - - - 2020-08-29, Grant Agreement terminated - - - 2017-08-30 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Netherlands - - - OptoFeedback - - - H2020-MSCA-IF-2016 - - - 751387 - - - - - ASTON UNIVERSITY - - - EUR 195 454,80 - - - Structured photonics for advanced fibre lasers - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The key goals of the project are: (1) the training of a talented, independent researcher, Dr Amos Martinez, to become a successful leading scientist in the fast growing field of science, technology and industrial applications - of fibre lasers, (2) exploring new ways to exploit two-dimensional materials, such as graphene, in photonics through femtosecond laser nanostructuring and developing new classes of light sources for applications in optical communications, medical - imaging, industrial manufacturing and metrology. This multidisciplinary project has great implications on laser science, nanotechnology, material science and graphene technologies such as graphene plasmonics, metamaterials, phononics and electronics, - and will involve both fundamental and applied research. - - - 2017-07-05, Grant Agreement terminated | - - - 2015-07-06 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SPAFIL - - - H2020-MSCA-IF-2014 - - - 659222 - - - - - THE UNIVERSITY OF EXETER - - - EUR 183 454,80 - - - Flexible Hyperspectral Infrared Detectors - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - One of the major driving forces for current research in electronics is the desire to realize the so-called internet of things, an autonomous information network that enables communication between objects without external human - intervention. To this end, much of the research effort in device physics is currently directed into sensors technology, and specifically, to photodetectors. The infrared (IR) region of the spectrum is of particular interest as it can carry - information about an object’s temperature, and its chemical composition. IR waves are also used for long-range waveguided communication, as well as short-range free space signaling. In IR systems, the readout noise is reduced by exploiting multicolor - IR detection, so-called hyperspectral IR, thus lowering false positive detection. - - 2018-09-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - FLAIR - - - H2020-MSCA-IF-2015 - - - 701704 - - - - - CONSIGLIO NAZIONALE DELLE RICERCHE - STAZIONE ZOOLOGICA ANTON DOHRN - THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN - UNIVERSITETET I TROMSOE - FUNDACION CENTRO DE EXCELENCIA EN INVESTIGACION DE MEDICAMENTOS INNOVADORES EN ANDALUCIA - SEALIFE PHARMA GMBH - ECOAST - EPI-C SRL - SEA4US BIOTECNOLOGIA E RECURSOS MARINHOS LDA - UNIVERSITY OF THE WESTERN CAPE - - - EUR 373 500 - - - Ocean Medicines - - - EUR 373 500 - - - Italy - Italy - United Kingdom - Norway - Spain - Austria - Belgium - Italy - Portugal - South Africa - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - Marine organisms have the capacity to produce a variety of biologically potent natural products. Such novel molecules have new mechanisms of action and therefore could be used to treat human diseases and enhance the quality of - life, especially in the ageing segment of the population. However, although there is growing interest in marine natural products (MNP) as potential therapeutic agents for human age-related diseases, few MNPs have reached clinical trials and the - market. To fully exploit these promising biological resources, new strategies in the pipeline as well as a new cohort of cross-disciplinary trained scientists are needed to overcome existing bottlenecks and ensure the production of high value - biomolecules. - - - 2019-11-30, ongoing project - - - 2015-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Italy - - - Ocean Medicines - - - H2020-MSCA-RISE-2015 - - - 690944 - - - - - THE UNIVERSITY OF EXETER - THE UNIVERSITY OF EXETER - - - EUR 1 931 730 - - - The Problem of European Misperceptions in Politics, Health, and Science:Causes, Consequences, and the Search for Solutions - - - EUR 1 931 730 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - While some people may simply lack relevant factual knowledge, others may actively hold incorrect beliefs. These factual beliefs that are not supported by clear evidence and expert opinion are what scholars call misperceptions - (Nyhan and Reifler 2010). This project is principally about misperceptions—the “facts” that people believe that simply are not true. What misperceptions do Europeans hold on issues like immigration, vaccines, and climate change? Who holds these - misperceptions? What demographic and attitudinal variables are correlated with holding misperceptions? And ultimately, what can be done to help reduce misperceptions? - - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - DEBUNKER - - - ERC-2015-CoG - - - 682758 - - - - - UNIVERSITETET I TROMSOE - UNIVERSITETET I TROMSOE - - - EUR 143 933 - - - A gene expression test in blood for breast cancer - - - EUR 143 933 - - - Norway - Norway - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The aim of BLOBREC is to develop a blood-based test for the diagnosis of breast cancer. The test is based on results from gene expression analyses in a hospital based nested case-control study in the Norwegian Women and Cancer - postgenome cohort study. The controls are healthy population controls from the same cohort. The innovative potential of a gene expression test is the independency from other test for breast cancer like imaging technologies (mammograms, ultrasound, - MR) and pathological diagnosis. As such it could be used by itself or in combination with these other technologies. The idea has been considered by the International Search Authorities to be novel and inventive and thus, considered to be patentable. - - 2016-04-30, closed project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2014 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Norway - - - BLOBREC - - - ERC-2014-PoC - - - 665633 - - - - - UNIVERSITY OF NEWCASTLE UPON TYNE - - - EUR 195 454,80 - - - Measuring Quality of Life in the general population and Roma minority in Romania: implications for health policies and economic evaluations - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The importance of health related quality of life (HRQoL) data in research, clinical practice and health policy has significantly increased over the past decade. EQ-5D-5L is one of the most widely used instruments to measure - HRQoL worldwide. Nevertheless, the quality of life of the Romanian general population or ethnic minorities has never been assessed before with EQ-5D-5L. Here, I propose to use EQ-5D-5L to provide locally robust HRQoL data for Romania to support - reimbursement decisions and public health interventions in wider and vulnerable groups, such as the Roma minority. A representative sample of the Romanian general population and Roma minority will be recruited and face-to-face interviews will be - conducted to explore differences in HRQoL according to sociodemographic characteristics, socioeconomic status and ethnicity. Additionally, population norms and social preferences for different health states (tariff) for EQ-5D-5L will be obtained. - - - 2019-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - QoLRO - - - H2020-MSCA-IF-2016 - - - 748612 - - - - - RUHR-UNIVERSITAET BOCHUM - RUHR-UNIVERSITAET BOCHUM - KOZEP-EUROPAI EGYETEM - - - EUR 1 999 623 - - - Jews and Christians in the East: Strategies of Interaction between the Mediterranean and the Indian Ocean - - - EUR 1 999 623 - - - Germany - Germany - Hungary - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project analyzes Jews in Eastern Christian communities and Eastern Christian sources, beyond the Byzantine context, namely, relations between Jews and Christian communities in the Middle East Central Asia, the Caucasus, - Ethiopia, and South India. In order to obtain a truly accurate understanding of the dynamics of Jewish-Christian relations in the non-Latin world during the Middle Ages, these various regions and traditions must be studied together because they were - all profoundly interconnected through the exchange and translation of texts, artistic motifs and techniques, and other goods, via long-distance trade along the “silk road”, the Mediterranean, and the Indian Ocean, which, of course, also entailed the - movement and encounter of peoples, Jews and Christians among them. The research team endeavors to answer four intertwined questions: 1) what we can know about actual “real-life” interactions between Jews and a variety of Eastern Christian - communities; 2) what were the meanings and functions of invented or rhetorical Jewish identities; 3) what is the significance of Jewish-Christian polemics, both written and visual, in lands or among communities where: a) there were supposedly few to - no Jews, or Jewish identity was “invented”; b) there were Jewish and Christian communities who had the opportunity to be in regular contact with one another; 4) how were Christian stories, laws, biblical interpretations, or motifs in which Jews - featured prominently, or Jewish tales and motifs about Christians transformed as they were transported from one cultural milieu to another? Because scholars have examined Jewish relations with Christians, and even Muslims primarily in the context of - uneven power relationships; namely Jewish-Christian relations in Western Europe or Byzantium, or Jewish-Muslim relations in the Islamic one leaving Jewish-Christian relations untouched apart from shared communal structures, this project opens a new - field. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - JEWSEAST - - - ERC-2014-CoG - - - 647467 - - - - - VIB - VIB - - - EUR 150 000 - - - employing protein aggregation as an antibacterial design strategy - - - EUR 150 000 - - - Belgium - Belgium - - - Research Organisations - Research Organisations - - Antibiotic resistance is increasing globally at such a pace that many experts fear the dawn of the post-antibiotic era if we fail to meet the urgent need for novel therapeutics. We evaluated if the working hypothesis of the - MANGO ERC project that protein aggregation is driven by sequence specific interactions can be exploited to generate aggregates that are specifically toxic to bacteria without affecting mammalian cells. In particular we examined if peptides encoding - aggregation-prone sequence segments of bacterial proteins can display antimicrobial activity by initiating aggregation in bacteria but not in mammalian cells. Unbiased in vitro screening of aggregating peptides lead to the identification of several - hits that are strongly bactericidal against drug resistant gram+ S aureus strains, and others against pathogenic gram- E coli strains. The peptides cured mice from bacterial sepsis without apparent toxic side effects. The peptides enter and - accumulate in the bacterial cytosol where they cause aggregation of bacterial polypeptides and the formation of inclusion bodies. Although the precise chain of events that leads to cell death remains to be elucidated, the ability to tap into - aggregation-prone sequences of bacterial proteomes to elicit antimicrobial activity represents a rich and unexplored chemical space to be mined in search of novel therapeutic strategies to fight infectious diseases that are increasingly threatening - global healthcare. However, given the novelty of this concept, the viability of aggregating peptides as antimicrobial therapeutics needs to be further advanced in order to consolidate the already significant interest from the pharmaceutical industry. - In the current proposal we outline a series of experiments designed to address some of the key questions that were raised by potential investors and experts from the pharmaceutical sector to whom we presented the current data package. - - 2018-12-31, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Belgium - - - PeptIn - - - ERC-2017-PoC - - - 766811 - - - - - OSRAM GMBH - UNIVERSITA DEGLI STUDI DI VERONA - - - EUR 507 277,80 - - - Time-lapse understanding of the static and human scene and its lighting - - - EUR 507 277,80 - - - Germany - Italy - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - Europe has a strong position in the fast-growing photonics and lighting industry but has to face the fast technological changes and, most importantly, a demand for larger transfer from research to industrial innovation and - application. With the introduction of Solid State Lighting (SSL) new targets of energy efficiency were set and smart lighting technology was boosted. - - 2019-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-EID - Marie Skłodowska-Curie Innovative Training Networks (ITN-EID) - - - MSCA-ITN-EID - European Industrial Doctorates - - - Germany - - - SCENEUNDERLIGHT - - - H2020-MSCA-ITN-2015 - - - 676455 - - - - - EUROPROXIMA BV - - - EUR 177 598,80 - - - Development of fast antibody-based screening tests for the detection of harmful mycotoxins in food and feed - - - EUR 177 598,80 - - - Netherlands - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The contamination of food and feed with harmful fungal derived mycotoxins is a problem worldwide and worsening. Over 400 different mycotoxins are now known, some of them have been studied in great detail, while the data about - toxicity and occurrence for many others are scarce. This information is required to determine the risk in relation to animal and human health and establish maximum permitted levels that do not pose any health concerns. The fast elimination of - contaminated food and feed from the supply chain is crucial for the protection of human and animal health as many of these toxins can cause serious diseases both after acute and chronic exposure. The occurrence data cannot be provided without fast - and reliable detection methods that allow quantification of these toxic contaminants. This research, therefore, is focused on delivering new fast antibody-based (ELISA) screening methods for the detection of three important mycotoxins: T-2/HT-2, - ochratoxin A and sterigmatocystin and on the development of a first multiplex flow-through rapid (FTR) test for the simultaneous detection of mycotoxins in food and feed. These tests could be used by food and feed producers, importers and testing - laboratories to assure food and feed safety on the European market. The researcher will work for two years with the food safety company EuroProxima (EP) in the Netherlands that will provide training and support of the development of the commercial - analytical assays. The project will be also supported by the partner organisations - Institute for Global Food Security (IGFS) at Queen's University Belfast (QUB) and RIKILT Wageningen UR (RIKILT) who will be hosting secondment phases in order to - facilitate the work packages. This project aims to combine academic excellence with specialist SME know-how to work on a project with significant impact on public health and that offers a substantial commercial opportunity. - - 2017-09-30, closed project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - MycoTest - - - H2020-MSCA-IF-2014 - - - 655119 - - - - - THE UNIVERSITY OF EXETER - - - EUR 183 454,80 - - - Complex parasite communities as drivers of bacterial immunity - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - CRISPR-Cas is one of several distinct bacterial defence mechanisms that provide immunity against viruses (phages) and other mobile genetic elements (MGEs; e.g. plasmids). My research aims at understanding how - CRISPR-Cas-mediated immunity is affected by the complexity of MGE communities. Using evolution assays and deep sequencing techniques I aim to study (i) the evolution of CRISPR-Cas-mediated immunity in a complex MGE community (i.e. multiple phages and - plasmids), and (ii) determine the associated co-evolutionary dynamics. The proposed research is highly multidisciplinary and will perfectly complement my background in biochemistry and molecular biology. It also allows me to establish collaborations - with academic and industrial partners to realize applications in dairy industry and phage therapy. The project will be pivotal for my personal development to become an independent researcher and offers me the unique opportunity to work in one of the - most prominent microbial ecology and evolution laboratories worldwide, based at the Biosciences Department at the University of Exeter. Biosciences is a leading institute in evolutionary biology, microbiology and ecology that provides excellent - opportunities for academic training and personal career development. I will be exposed to novel ideas and input from renowned researchers belonging to scientific disciplines unrelated to my own background, offering exciting opportunities for - knowledge exchange and will have a strong impact on my personal and scientific development. Furthermore, I aim to establish a series of lectures for the general public throughout 2015 (the Year of the Phage) to emphasize the importance of phage - research for many aspects of our society, including industry and medicine. - - 2017-12-31, closed project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - PHAGECOM - - - H2020-MSCA-IF-2014 - - - 660039 - - - - - TECHNISCHE UNIVERSITAET GRAZ - UNIWERSYTET WARMINSKO MAZURSKI W OLSZTYNIE - UNIVERZA V MARIBORU - UMEA UNIVERSITET - MEDIZINISCHE UNIVERSITAT GRAZ - - - EUR 2 463 975 - - - Contrast by Quadrupole Enhanced Relaxation - - - EUR 2 463 975 - - - Austria - Poland - Slovenia - Sweden - Austria - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The ageing society and demographic change is one of the major challenges which Europe is facing now, and even more so in the future. Mastering this challenge requires radically new diagnostic and therapeutic treatments as key - factors in achieving the healthy well-being of European citizens. Molecular imaging (MI) plays a pivotal role in diagnosis, understanding of disease and in the development of effective treatments. - - - 2018-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-1-2014 - FET-Open research projects - - - RIA - Research and Innovation action - - - Austria - - - CONQUER - - - H2020-FETOPEN-2014-2015-RIA - - - 665172 - - - - - THE UNIVERSITY OF EXETER - - - EUR 195 454,80 - - - Transgenerational Ecophysiological Responses to Multiple Stressors in a changing Ocean - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Global oceans are currently changing at a faster rate than at any other time over the last 300 million years, exposing marine organisms to multiple environmental stressors, such as climate change and ocean acidification (OA). - Coastal marine invertebrates are globally important in terms of the ecosystem services and functions that they provide, hence it is vital to determine whether they can adapt and evolve to cope with these multiple stressors at the rate at which they - are occurring. The TERMS-Ocean project will address this key question by determining the role of transgenerational phenotypic plasticity (TPP) in the response of a keystone marine invertebrate to the combined impacts of climate change and OA. TPP - examines the potential for phenotypic plasticity in offspring in response to parental stress and has been shown to alleviate physiological responses in single-stressor studies; however there is no evidence to date as to whether TPP can operate when - multiple stressors are experienced in combination. Here, a novel common garden experimental design will be employed to examine the transgenerational responses of the sea urchin Paracentrotus lividus to the combined effects of elevated temperature and - OA in order to assess whether TPP plays a role in alleviating the effects of these stressors when experienced in combination. This project will be pivotal for my personal development to become an independent researcher and offers me the unique - opportunity to work in a top 10 Russel Group University with a global reputation for excellence in environmental and climate change research. Exeter Biosciences is a leading institute in environmental biology and ecology and provides excellent - opportunities for academic training and personal career development. A fellowship at Exeter will expose me to novel ideas and input from renowned researchers, offer me exciting opportunities for knowledge exchange, and have a strong impact on my - personal and scientific development. - - 2018-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - TERMS-Ocean - - - H2020-MSCA-IF-2015 - - - 704895 - - - - - THE UNIVERSITY OF EXETER - - - EUR 183 454,80 - - - Christian Diversity in Late Antique Sirmium (ca 350 – ca 450): A Historical, Literary and Theological Study - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - This research follows a Christian community situated on the edge of Central Europe and the Balkans during an intense period of struggles towards its self-definition amongst religious dissent, socio-cultural diversity and - political and military hardships. All these resulted in a regionally coloured Christianity, the main characteristics of which are visible in the material as well as literary heritage of this community. The setting is the 4th - 5th century A.D. - Sirmium – modern Sremska Mitrovica (Serbia). At the time, Sirmium was one of the capitals of the Roman province Pannonia, an area which now comprises parts of modern Austria, Hungary, Croatia and Serbia. It is vital to understand the history of - religious diversity and identity in that region, which continues to puzzle Europe with its rich cultural heritage, but also with its controversial political, ethnical and religious past. This research will contribute to the better understanding of - European culture, and its religious and cultural memory, reinforcing the idea that the concrete realization of Christian identity varies according to context and that there is a complex relationship between religious diversity and identity in a - particular place. Once verified with regard to Sirmium, this type of research can be extended to other places / regions in the late antique Mediterranean world. In particular, the applicant envisages a long-term research project on Christian identity - in Roman Pannonia and a network of late antique Middle Danube studies. All these will lead to the pursuit of a tenure-track academic position that will enable the applicant to implement this larger Pannonian research. The University of Exeter is the - ideal location: it is a growing centre of Late Antique studies, with a cluster of research projects on ‘Identities and beliefs’ in the ancient world. The fellow will extend her skills by being in Exeter, and will contribute her linguistic and - historical expertise to their on-going research. - - 2018-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - CHRISLAS - - - H2020-MSCA-IF-2014 - - - 658265 - - - - - THE UNIVERSITY OF EXETER - - - EUR 183 454,80 - - - Significant or trivial: Fungi in Polar Ecosystems - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Fungi are major components of the Earth's biosphere, playing a pivotal role as decomposers and recyclers of nutrients across different environments. However, fungal diversity and function in marine environments has been poorly - studied, leading to a biased picture of fungal distribution. Latest studies indicated a distinct marine fungal diversity, including chytrids which can affect algae and zooplankton communities because of their parasitic lifestyle or function as food - source. The project intends to investigate the importance of marine fungi in polar-regions, environments that promote the occurrence of endemism and thus the detection of novel species. WP1 aims to study marine fungal diversity and distribution and - to provide novel and unique information on the influence of environmental variables on the biodiversity of fungi in these important and changing environments. Two hypotheses will be tested in this work package: firstly, are the fungi identified - representative of 'bona-fide' marine lineages and not land-derived origin? Secondly, do fungi represent a higher diversity in marine polar waters compared to temperate and tropical waters? WP2 aims to elucidate the genes transcribed by polar fungi in - these atypical and cold environments. This work will allow me to understand the biological characteristics of these fungi that underpin their diversity and distribution profiles by using comparative meta-transcriptomic analysis of environments rich - in polar chytrid lineages. Once both work packages are brought together they will help to fill the gap in our understanding of the marine environment, providing important information on ecology of marine communities. Polar environments are undergoing - unprecedented changes, it is therefore crucial to understand important components of the microbial community, specifically fungi. The combination of diversity analysis and reconstruction of biological function will uniquely allow for such progress. - - 2018-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - F-Pole - - - H2020-MSCA-IF-2014 - - - 657141 - - - - - UNIVERSITA DEGLI STUDI DI VERONA - - - EUR 180 277,20 - - - The 4th Geneva Convention’s Drafting History as the origin of the Responsibility to Protect (R2P) and Duty to Prevent (D2P). - - - EUR 180 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - The objective of this project is to uncover the source materials of current humanitarian norms (Responsibility to Protect and Duty to Prevent) within the first and most important tool of International Humanitarian Law – the - 4th Geneva Convention for the Protection of Civilians (1949). Specifically, this project aims to generate a comprehensive historical and legal account of the drafting process and of the 4th Geneva Convention, as to date, no such comprehensive account - exists. The research agenda envisages an innovative Multi factor framework approach, examining alongside the Red Cross archives in Geneva, the important National Archives of the US, France, the UK and Switzerland (the Conventions’ Custodian), who all - advocated and pushed for the Convention’s endorsement after WWII. The recent opening of national archives, following the lifting of the 50 year disclosure ban provides unprecedented access to hitherto unpublished materials, which could shed - much-needed light upon our comprehension of the Convention’s terms and legal interpretation, based upon the original intentions of the drafters. With the interpretation of this convention deeply contested in both judicial and policy circles, - uncovering the original drafting sources of the 4th Geneva Convention’s, could shed much needed light on questions regarding the nature of military occupation, of judicial oversight over armed conflict, and of the attitudes to be attributed to - irregular fighting forces and non state actors. Recent events, most notably in the Middle East and North Africa point to an alarming tendency of the erosion of any limits to armed conduct. This process goes hand in hand with the exponential surge in - civilian casualties in these armed conflicts. Uncovering the original sources which motivated drafters to limit war – while accepting its existence as a feature of human nature is all the more timely and relevant today. - - 2018-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - REQUE 2 - - - H2020-MSCA-IF-2015 - - - 701275 - - - - - UNIVERSITY OF GLOUCESTERSHIRE - - - EUR 162 879 - - - Situated Learning Opportunities fostered by ICT applications in Alternative Agro-Food Networks - - - EUR 162 879 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The training-through-research project SOFIA - Situated Learning Opportunities fostered by ICT applications in Alternative Agro-Food Networks- aims at enhancing the researcher potential to make broad his horizons and support - his career development. In the light of his research objectives he will acquire new knowledge and transfer that one previously developed to the host organization The SOFIA project will allow the ER to became a key facilitator of multidisciplinary - research and innovation teams, applying his interdisciplinary competences in service design for innovation, thus ensuring an independent position to the researcher and his future employability in the academic and/or non-academic context. The research - SOFIA aims to analyze innovative organizational models and explore the value of the use of ICT tools (e.g. ubiquitous mobile services) to increase Situated Learning Opportunities (SLOs) in an Alternative Agro-Food Networks (AAFNs), through two - methodologies i.e multi-case study analysis of local food systems and rural areas and a web-survey of ICT tools for AAFN. The expected impact of the research is to define a set of reproducible methodologies, models, tools and technologies that can - improve the competitiveness of a selected area, leveraging its potential in terms of materials and intangible resources. In addition, the study will aim to analyze ICT tools supporting the information flows management both for decision making and for - operational processes in the identified collaborative networks. - - 2018-01-31, closed project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SOFIA - - - H2020-MSCA-IF-2015 - - - 702884 - - - - - INSTITUTE OF FOOD RESEARCH - UNIVERSITY OF EAST ANGLIA - - - EUR 183 454,80 - - - Elucidating how Bifidobacteria shapes the microbiota in response to infant diet. - - - EUR 183 454,80 - - - United Kingdom - United Kingdom - - - Research Organisations - Higher or Secondary Education Establishments - - After birth we are colonized by a consortium of bacteria that are critical for health. Bifidobacteria represent pioneer members, and reach high levels within the gut microbiota of breast-fed infants. These bacteria are - proposed to be critical for establishing ‘healthy’ microbiota development and immune defense; however the mechanisms remain unknown. We hypothesize that breast-milk metabolism by Bifidobacteria provides microbial-derived metabolic products key to - promoting stable colonisation of other members in the microbiota, suggesting a mechanism as to why formula-fed infants have an altered microbiota and associated increased risk to a variety of diseases. This MCSA seeks to elucidate the function of - Bifidobacteria with host diet, by developing a model colon ecosystem colonised with defined infant bacterial isolates to identify key bifidobacterial-derived metabolic byproducts that differ between breast milk and formula metabolism using - cutting-edge metabolic tracer experiments and [13C]-Bifidobacteria pseudocatenulatum. Aim 2 will determine the genomic and regulatory elements in B. pseudocatenulatum required for adaption/metabolism of breast-milk or infant formula in the model - colon via construction of a genome-wide mutant library generated by high through-put transposon mutagenesis. Metabolites identified in aim 1 will be linked to specific bifidobacterial gene function, based on the identity of essential mutants unable - to grow in the presence of breast-milk (aim 2). We will also determine how host diet impacts microbiota composition in the model ecosystem, by monitoring microbial diversity by 16S rRNA analysis. Finally, to promote a ‘healthy’ microbiota, identified - breast-milk metabolites will be used to supplement the formula fed model. This research will provide critical insight into the function and mechanism of how infant diet impacts bifidobacteria colonisation, with the potential to identify key - bifidobacterial-metabolites that promote life-long health. - - 2017-06-30, closed project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - INFANT MICROBIOTA - - - H2020-MSCA-IF-2014 - - - 661594 - - - - - THE UNIVERSITY OF EXETER - - - EUR 183 454,80 - - - Structure – Oxidative Stress relationships of metal oxide nanoparticles in the aquatic environment - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The SOS-Nano project will address one of the most pressing cutting edge issues of econanotoxicology at present: to find a structural property of nanoparticles (NPs) to predict their potential toxicity in real aquatic - environments, the final sink of released NPs. By using an in vivo natural water exposure system, SOS-Nano will test the suitability of two paradigms, recently demonstrated effective in vitro for ranking the hazard of metal oxide NPs: 1) NPs - physical-electrochemical properties for predicting oxidative stress potential, and 2) oxidative stress generation for predicting biological impact. - - - 2017-10-31, closed project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SOS-Nano - - - H2020-MSCA-IF-2014 - - - 655134 - - - - - UNIVERSITA DEGLI STUDI DI VERONA - - - EUR 168 277,20 - - - DOES IT PROMOTE ECONOMY AND WELL-BEING? THE IMPACT OF TELEWORKING ON ENVIRONMENT AND LABOUR MARKET OUTCOMES - - - EUR 168 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - This project examines the telework effects on environment and labour market outcomes. More specifically, the first aim of the project is to analyse the link between job satisfaction, labour productivity and firm performance. - The second aim is to examine the effects of teleworking on labour productivity/job satisfaction and environment (e.g. traffic, air pollution). The final aim of this study is to examine how teleworking affects the labour market and housework division - between men and women. Two databases are used; the Workplace Employment Relations Survey (WERS) and British Household Panel Survey (BHPS). Various econometric techniques are applied, such as Fixed Effects and Dynamic Generalized Methods of Moments - (GMM) models Instrumental Variables (IV) and Generalized Latent Class Ordered Probit Models, Seemingly Unrelated Regressions (SURE) and Three Stage Least Squares (3SLS). - - 2017-05-31, closed project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - TELE - - - H2020-MSCA-IF-2014 - - - 652938 - - - - - THE UNIVERSITY OF EXETER - THE UNIVERSITY OF EXETER - - - EUR 1 499 997,50 - - - Ecological and evolutionary constraints on the temperature dependence of the carbon cycle - - - EUR 1 499 997,50 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The cycling of carbon between the biosphere and the atmosphere is mediated by its transformation and flux through ecosystems. Atmospheric CO2 is fixed by photosynthesis, exchanged between organisms via their interactions, and - re-emitted to the atmosphere through the by-products of their metabolism (CO2). These metabolic processes are inherently temperature dependent, and consequently there is potential for elevated rates of respiration (CO2 production) in a warmer world - to further accelerate global warming. However, large uncertainties about the magnitude of any response exist, owing to limited understanding of the mechanisms underpinning the temperature dependence of ecosystem metabolism. I approach this problem - from a new perspective, by proposing that interactions between evolutionary processes, which influence the frequency and variance of metabolic traits within populations, and ecological interactions between populations, which shape the structure and - dynamics of communities, constrain the overall temperature dependence of metabolic fluxes at the ecosystem-level. I will ask: How do differences in thermal responses and the nature of ecological interactions between species influence the temperature - response of an ecosystem? What is the rate and magnitude of thermal adaptation? Does coevolution in a community affect thermal adaptation? How do differences in thermal responses and turnover in species composition affect the temperature dependence - of ecosystems? I will answer these questions with an array of experiments that recombine microbes isolated from a long-term freshwater warming experiment (+4°C for 10 years) in communities in the laboratory. This project will break new ground in - understanding how patterns and processes at the ecosystem-level emerge from the dynamics of populations and communities over ecological and evolutionary timescales. At the same time, it will contribute substantially to understanding carbon cycle - responses to global warming. - - 2021-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - TEMPDEP - - - ERC-2015-STG - - - 677278 - - - - - THE UNIVERSITY OF EXETER - THE UNIVERSITY OF EXETER - - - EUR 2 206 205 - - - Accretion, Winds, and Evolution of Spins and Magnetism of Stars - - - EUR 2 206 205 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project focuses on Sun-like stars, which possess convective envelopes and universally exhibit magnetic activity (in the mass range 0.1 to 1.3 MSun). The rotation of these stars influences their internal structure, energy - and chemical transport, and magnetic field generation, as well as their external magnetic activity and environmental interactions. Due to the huge range of timescales, spatial scales, and physics involved, understanding how each of these processes - relate to each other and to the long-term evolution remains an enormous challenge in astrophysics. To face this challenge, the AWESoMeStars project will develop a comprehensive, physical picture of the evolution of stellar rotation, magnetic - activity, mass loss, and accretion. - - 2021-06-30, ongoing project - - - 2016-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - AWESoMeStars - - - ERC-2015-CoG - - - 682393 - - - - - THE UNIVERSITY OF EXETER - THE UNIVERSITY OF EXETER - - - EUR 2 212 638,60 - - - Law, Authority and Learning in Imami Shi'ite Islam - - - EUR 2 212 638,60 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The academic study of Islamic law has, so far, almost exclusively focused on Sunni legal thought. The legal thought and practice of Shi’ite (and other) traditions has been neglected, and this has created a rather skewed - account of the history of Islamic law. This project aims to rectify this inadequacy by producing a body of research in which the Imami Shi’ite contribution to Islamic legal history is described, analysed and evaluated. Imami Shi’ites, sometimes - termed Twelvers, are the largest branch of Shi’ism today. Imamis form a majority in Iran and Iraq where the major Shi’i centres of legal learning are located. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - LAWALISI - - - ERC-2015-AdG - - - 695245 - - - - - THE UNIVERSITY OF EXETER - THE UNIVERSITY OF EXETER - - - EUR 1 252 067 - - - Fair and Consistent Border Controls? A Critical, Multi-methodological and Interdisciplinary Study of Asylum Adjudication in Europe - - - EUR 1 252 067 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - ‘Consistency’ is regularly cited as a desirable attribute of border control, but it has received little critical social scientific attention. This inter-disciplinary project, at the inter-face between critical human geography, - border studies and law, will scrutinise the consistency of European asylum adjudication in order to develop richer theoretical understanding of this lynchpin concept. It will move beyond the administrative legal concepts of substantive and procedural - consistency by advancing a three-fold conceptualisation of consistency – as everyday practice, discursive deployment of facts and disciplinary technique. In order to generate productive intellectual tension it will also employ an explicitly - antagonistic conceptualisation of the relationship between geography and law that views law as seeking to constrain and systematise lived space. The project will employ an innovative combination of methodologies that will produce unique and rich data - sets including quantitative analysis, multi-sited legal ethnography, discourse analysis and interviews, and the findings are likely to be of interest both to academic communities like geographers, legal and border scholars and to policy makers and - activists working in border control settings. In 2013 the Common European Asylum System (CEAS) was launched to standardise the procedures of asylum determination. But as yet no sustained multi-methodological assessment of the claims of consistency - inherent to the CEAS has been carried out. This project offers not only the opportunity to assess progress towards harmonisation of asylum determination processes in Europe, but will also provide a new conceptual framework with which to approach the - dilemmas and risks of inconsistency in an area of law fraught with political controversy and uncertainty around the world. Most fundamentally, the project promises to debunk the myths surrounding the possibility of fair and consistent border controls - in Europe and elsewhere. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - ASYFAIR - - - ERC-2015-STG - - - 677917 - - - - - THE UNIVERSITY OF EXETER - - - EUR 195 454,80 - - - All-organic devices in textiles for wearable electronics - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - We are surrounded by fabrics, the carpet floors in our homes or offices, the seats in our cars, and obviously all our garments and clothing accessories. There are already examples of smart textiles in garments for monitoring - physiological and biomechanical signals. However, the manufacturing schemes for current applications rely mostly on the integration of off-the-shelf electronic components mounted on a textile substrate. Such components are silicon-based, thus - unsuitable for applications where flexibility and fault-tolerance are required. - - - 2018-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - E-TEX - - - H2020-MSCA-IF-2015 - - - 704963 - - - - - THE UNIVERSITY OF EXETER - THE UNIVERSITY OF EXETER - ROTHAMSTED RESEARCH LIMITED - - - EUR 1 975 512 - - - Understanding and exploiting the insect P450 resistome - - - EUR 1 975 512 - - - United Kingdom - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - Insect resistance to synthetic insecticides and the anti-herbivore defence chemicals produced by many plants is an ongoing challenge to sustainable pest management while also an exceptional model system to study adaptive - evolution. The cytochrome P450s are a superfamily of enzymes that are ubiquitous in nature, and one of the most important enzyme families used by insects to defend themselves against natural and synthetic xenobiotics. Insects have been shown to - evolve resistance through quantitative changes in P450 expression or via qualitative changes in P450s that alter metabolic activity. Despite their importance in conferring resistance the variety of regulatory changes that modulate P450 expression in - resistant insects and their relative frequency/impact is not fully understood. Furthermore, although qualitative changes in insect P450s associated with resistance are relatively rare they represent a unique opportunity to characterise - insecticide/toxin binding and identify the critical structure/function determinants of the P450/insect toxin interaction. - - 2020-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - P450RESIST - - - ERC-2014-CoG - - - 646625 - - - - - UNIVERSITAT KONSTANZ - UNIVERSITAT KONSTANZ - - - EUR 1 918 600 - - - Discovery of novel orphan riboswitch ligands - - - EUR 1 918 600 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Riboswitches are mRNA-based gene-regulatory elements triggered by direct interactions with small molecular ligands. They are exciting targets for novel antibiotic strategies. Many putative riboswitches have been identified - using bioinformatics. However, ligand identification is getting more complicated since many motifs are not expected to be involved in simple feedback regulation mechanisms. For such “classical” riboswitches ligands have been assigned in the past - based on testing metabolites selected by educated guesses guided by the associated gene contexts. We are convinced that this approach limits the identification of riboswitches that play regulatory roles in more complex bacterial processes such as - virulence, detoxification, communication, and life style adaptations. Within this project, new riboswitch classes will be identified and characterized, paving the way for the development of antibiotics with novel modes of action. - - 2021-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - RiboDisc - - - ERC-2015-CoG - - - 681777 - - - - - UNIVERSITAT KONSTANZ - UNIVERSITAT KONSTANZ - - - EUR 1 497 000 - - - Artificial Natural Products System Synthesis - - - EUR 1 497 000 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - "Traditionally, natural products are classified into "natural product families". Within a family all congeners display specific structure elements, owing to their common biosynthetic pathway. This suggests a bio-inspired or - "collective synthesis", as has been devised by D: W. MacMillan. However, a biosynthetic pathway is confined to these structure elements, thus limiting synthesis with regard to structure diversification. In this research proposal the applicant - exemplarily devises a strategic concept to overcome these limitations, by replacing the dogma of "retrosynthetic analysis" with "structure pattern recognition". This concept is termed "Artificial Natural Product Systems Synthesis — ANaPSyS", and aims - to supersede the current "logic of chemical synthesis" as a standard practice in this field. - - 2021-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - ANaPSyS - - - ERC-2015-STG - - - 679418 - - - - - UNIVERSITA DEGLI STUDI DI VERONA - UNIVERSITA DEGLI STUDI DI VERONA - - - EUR 2 500 000 - - - The role of immune cells in Alzheimer's disease - - - EUR 2 500 000 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - "Alzheimer’s disease is the most common form of dementia affecting more than 35 million people worldwide and its prevalence is projected to nearly double every 20 years with tremendous social and economical impact on the - society. There is no cure for Alzheimer's disease and current drugs only temporarily improve disease symptoms. - - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Italy - - - IMMUNOALZHEIMER - - - ERC-2015-AdG - - - 695714 - - - - - THE UNIVERSITY OF EDINBURGH - THE UNIVERSITY OF EDINBURGH - THE UNIVERSITY OF EXETER - - - EUR 1 550 235 - - - Evolutionary genetics of guppy sex chromosomes - - - EUR 1 550 235 - - - United Kingdom - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - I propose an integrated programme of molecular genetic studies to fill fundamental gaps in our knowledge of sex chromosome evolution. Specifically, I will use a fish, the guppy (Poecilia reticulata), to test the sexual - antagonism (SA) hypothesis of sex chromosome evolution, which is plausible, but lacks direct evidence. SA mutations (that benefit one sex but lower fitness of the other) are proposed to arise in a partially sex-linked (pseudo-autosomal region, or - PAR) gene, and establish polymorphisms. To reduce the conflict between the sexes, suppressed recombination between X and Y chromosomes then evolves (unless sex-specific expression evolves first). The guppy is ideal for studying this hypothesis - because SA polymorphisms are well documented: male coloration phenotypes make males attractive to females, but also make them conspicuous to predators (while females gain no compensating benefit). Moreover, guppies have a recombination-suppressed - sex-linked region that carries multiple coloration genes, yet is thought to have evolved recently. However, no non-Y-linked coloration factor has yet been mapped, and the genetics is complicated by modifers making some XX individuals male, and by - male-specific expression of some phenotypes. I will map coloration genes and identify PAR genes using DNA-based markers to take account of these problems. I will test for the predicted lower coloration allele frequencies in natural populations with - high versus low predation rates, and do population genetic analyses to test for closer linkage under high predation. I will also use X-Y sequence divergence to estimate the age of the guppy sex chromosome. The project tests predictions that emerge - from well-documented differing selection regimes in natural guppy populations. I have therefore assembled a team of collaborators experienced with guppies who can provide behavioural and ecological genetic expertise to complement the strength of my - own group in molecular evolutionary genetics. - - 2020-07-31, ongoing project - - - 2016-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - GUPPYSEX - - - ERC-2015-AdG - - - 695225 - - - - - THE UNIVERSITY OF EXETER - THE UNIVERSITY OF EXETER - ADDIS ABABA UNIVERSITY - KATHOLIEKE UNIVERSITEIT LEUVEN - - - EUR 1 031 105 - - - Becoming Muslim: Conversion to Islam and Islamisation in Eastern Ethiopia - - - EUR 1 031 105 - - - United Kingdom - United Kingdom - Ethiopia - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - "Why do people convert to Islam? The contemporary relevance of this question is immediately apparent. "Becoming Muslim" will transform our knowledge about Islamisation processes and contexts through archaeological research in - Harar, Eastern Ethiopia, and examine this in comparison to other regions in sub-Saharan Africa via publication and a major conference. Assessing genuine belief is difficult, but the impact of trade, Saints, Sufis and Holy men, proselytisation, - benefits gained from Arabic literacy and administration systems, enhanced power, prestige, warfare, and belonging to the larger Muslim community have all been suggested. Equally significant is the context of conversion. Why were certain sub-Saharan - African cities key points for conversion to Islam, e.g. Gao and Timbuktu in the Western Sahel, and Harar in Ethiopia? Archaeological engagement with Islamisation processes and contexts of conversion in Africa is variable, and in parts of the - continent research is static. This exciting 4-year project explores, for the first time, Islamic conversion and Islamisation through focusing on Harar, the most important living Islamic centre in the Horn of Africa, and its surrounding region. - - 2020-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - BM - - - ERC-2015-AdG - - - 694254 - - - - - UNIVERSITA DEGLI STUDI DI VERONA - UNIVERSITA DEGLI STUDI DI VERONA - POLITECNICO DI MILANO - - - EUR 1 441 875 - - - IMPROVING PHOTOSYNTHETIC SOLAR ENERGY CONVERSION IN MICROALGAL CULTURES FOR THE PRODUCTION OF BIOFUELS AND HIGH VALUE PRODUCTS - - - EUR 1 441 875 - - - Italy - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Solar Energy is the most abundant renewable energy source available for our Planet. Light energy conversion into chemical energy by photosynthetic organisms is indeed the main conversion energy step, which originated high - energy containing fossil deposits, now being depleted. By the way, plant or algae biomass may still be used to produce biofuels, as bio-ethanol, bio-diesel and bio-hydrogen. Microalgae exploitation for biofuels production have the considerable - advantages of being sustainable and not in competition with food production, since not-arable lands, waste water and industrial gasses can be used for algae cultivation. Considering that only 45% of the sunlight covers the range of wavelengths that - can be absorbed and used for photosynthesis, the maximum photosynthetic efficiency achievable in microalgae is 10%. On these bases, a photobioreactor carrying 600 l/m-2 would produce 294 Tons/ha/year of biomass of which 30% to 80%, depending on - strain and growth conditions, being oil. However this potential has not been exploited yet, since biomass and biofuels yield on industrial scale obtained up to now were relatively low and with high costs of production. The main limitation encountered - for sustained biomass production in microalgae by sunlight conversion is low light use efficiency, reduced from the theoretical value of 10% to 1-3%. This low light use efficiency is mainly due to a combined effect of reduced light penetration to - deeper layers in highly pigmented cultures, where light available is almost completely absorbed by the outer layers, and an extremely high (up to 80%) thermal dissipation of the light absorbed. This project aims to investigate the molecular basis for - efficient light energy conversion into chemical energy, in order to significantly increase the biomass production in microalgae combining a solid investigation of the principles of light energy conversion with biotechnological engineering of algal - strains. - - 2021-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Italy - - - SOLENALGAE - - - ERC-2015-STG - - - 679814 - - - - - QUEEN MARY UNIVERSITY OF LONDON - - - EUR 251 857,80 - - - Legitimacy, Sovereignty and the Public Sphere - - - EUR 251 857,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The goal of the research is to redefine the interrelations between the concepts of legitimacy, sovereignty, the public sphere and democracy in order to develop a conception of a more inclusive and participatory public sphere. - - 2020-02-29, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - Legitimacy - - - H2020-MSCA-IF-2015 - - - 704479 - - - - - ASTON UNIVERSITY - UNIVERSIDADE DE AVEIRO - UNIVERSITAET LEIPZIG - UNIVERSITA DEGLI STUDI DI MILANO - VIB - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - CENTRO CARDIOLOGICO MONZINO - INSTITUTO PORTUGUES DO SANGUE E DA TRANSPLANTACAO IP - MOLOGIC LTD - THERMO FISHER SCIENTIFIC (BREMEN) GMBH - CENTRO HOSPITALAR E UNIVERSITARIO DE COIMBRA E.P.E. - - - EUR 3 545 010,72 - - - MASS Spectrometry TRaining network for Protein Lipid adduct ANalysis - - - EUR 3 545 010,72 - - - United Kingdom - Portugal - Germany - Italy - Belgium - Spain - Italy - Portugal - United Kingdom - Germany - Portugal - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - - MASSTRPLAN will train the next generation of interdisciplinary research leaders in advanced molecular analytical techniques to detect oxidized phospholipids & proteins in biological & clinical samples, evaluate their - biochemical roles in inflammation, and translate these findings to develop new diagnostic tools. - - - 2019-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - MASSTRPLAN - - - H2020-MSCA-ITN-2015 - - - 675132 - - - - - UNIVERSITAT KONSTANZ - - - EUR 171 795,60 - - - Perceiving the intentions of the weakest link: How attributed individual and collective goals impact reactions to low performers in groups - - - EUR 171 795,60 - - - Germany - - - Higher or Secondary Education Establishments - - Group work has become increasingly important for many tasks and services in organisations, and organisations thus depend on successful team function. The entire group’s performance may depend on the lowest performer (weakest - link), but groups’ reactions to low performers are not well understood. We suggest that goal attributions are a neglected but potentially powerful factor: Did the low performer try to outperform others (individual goal) or contribute to the group - (collective goal)? In the next step, groups should evaluate whether low performers were trying to succeed (but had insufficient abilities) or were not trying (i.e., had low goal commitment). Failing despite trying will lead to excluding competitive - low performers (individual goal) but lead to training cooperative low performers (collective goal). Vice-versa, lack of commitment to the collective goal to cooperate should lead to exclusion, but in attempts to change the individual goal of a - competitive low performer (socialisation). These hypotheses will be tested in a series of four experiments to attain the objectives of complementing Dr. Thürmer’s skillset in (1) small group theory, (2) small group laboratory experiments, (3) - transformative multilevel statistics, and (4) to advance the translational transfer to organizational settings. Publications in leading peer-reviewed scientific journals will disseminate the research results widely. The proposed action will open up - the immediate career opportunity to establish his independent research group, will substantially advance his research program, and is a crucial step towards becoming a full professor in Germany. Acquired start-up funding enables extensive pre-testing - and will ensure the success of this action. This trans-disciplinary research project will contribute to motivation science, small group research, and organizational science and the findings will help European organisations that rely on group work to - improve team functioning. - - 2018-08-31, ongoing project | - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Germany - - - Goal Attribution in Groups - - - H2020-MSCA-IF-2015 - - - 703042 - - - - - THE UNIVERSITY OF EXETER - THE UNIVERSITY OF EXETER - THE UNIVERSITY OF SUSSEX - - - EUR 2 424 263 - - - SHARING A GENOME: CASTE ANTAGONISM AND COADAPTATION IN SOCIAL INSECTS - - - EUR 2 424 263 - - - United Kingdom - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Eusociality, in which workers sacrifice their own reproduction to rear the offspring of queens, is a major focus of interest in evolutionary biology. A key aim during recent decades has been to understand the conflicts of - interest within eusocial groups. In contrast, however, little is known about the underlying genetic architecture. In this proposal, we will use a mixture of field experiments and transcriptomics to address novel questions about the evolutionary - dynamics of queen-worker interactions. Borrowing concepts from the field of sexual conflict, we will investigate a new idea: that the productivity of social groups is limited because castes are constrained by inter-caste genetic correlations from - simultaneously reaching their optimal (dimorphic) phenotypes. We will also quantify caste dimorphism across an environmental gradient, and investigate the plasticity of dimorphism using transplants and social manipulations. In addition, we will - cross-foster individuals between nests to test for coadaptation between queens and workers. And we will test a long-standing hypothesis experimentally for the first time: that queens manipulate worker phenotype in their own interests. - - - 2021-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - CASTECON - - - ERC-2015-AdG - - - 695744 - - - - - THE UNIVERSITY OF EXETER - THE UNIVERSITY OF EXETER - UNIVERSITA DEGLI STUDI DI MILANO - - - EUR 1 792 778 - - - Procedural Tools for Effective Growth (PROTEGO) Patterns, Outcomes and Policy DesignProcedural Tools for Effective Growth: Patterns, Outcomes and policy Design - - - EUR 1 792 778 - - - United Kingdom - United Kingdom - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - PROTEGO arises out of a fundamental claim: procedural regulatory instruments have causal effects on the performance of political systems because they trigger accountability towards different stakeholders. The mix of policy - instruments may be functional or dysfunctional, depending on how accountability mechanisms are combined. This project provides a theoretical rationale to capture the accountability effects by adopting an extension of delegation theory that considers - multiple stakeholders. The theoretical framework will allow us to identify the key social mechanisms that make bureaucracies internalize the preferences of accountees. We will test the observable implications of the framework on outcomes that are - crucial to the performance of political systems, such as trust in government, ease of business, control of corruption, sustainability. Empirically, we will collect, validate and analyze original data across the EU and its 28 Member States for the - period 2000-2015, distinguishing between instruments that cover central departmental activity and independent regulatory agencies. The new dataset will cover administrative procedure acts, freedom of information, notice and comment, judicial review, - impact assessment, environmental appraisal, and non-financial instruments for public spending accountability. These are the procedural instruments that enfranchise accountees. The bivariate relationship between a single instrument and outcomes - explains little – because it’s the overall ecology or mix of instruments that produces causal effects. These ecologies combine in different sequences and paths associated with the outcome. Hence we will draw on a suitable methodological approach - - Qualitative Comparative Analysis (QCA). Causality and diffusion across time will be also explored via event-history analysis and principal component analysis. PROTEGO will contribute to theories of regulation and accountability, and provide a robust - operational model of data and analysis. - - 2020-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - PROTEGO - - - ERC-2015-AdG - - - 694632 - - - - - THE UNIVERSITY OF EXETER - THE UNIVERSITY OF EXETER - - - EUR 1 968 392,05 - - - The Evolution of Competition and Cooperation: how polymorphisms in microbial populations optimise virulence and mediate drug resistance - - - EUR 1 968 392,05 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Microbes form intricate communities where multiple strains and species communicate cooperate and compete, they can cause life-threatening diseases and destroy our food sources. Metabolism is key to these interactions, yet the - way microbes acquire and utilise nutrients is often overlooked in evolutionary studies of pathogenicity, virulence and antibiotic resistance. I will address this by quantifying how microbial community composition is determined by the metabolism, - genetics and physiology of individual players, establishing principles by which microbial composition affects virulence and antimicrobial resistance. - - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - MathModExp - - - ERC-2014-CoG - - - 647292 - - - - - THE UNIVERSITY OF EXETER - - - EUR 183 454,80 - - - Rivers as leak in the terrestrial C sink - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Lateral displacement of carbon (C) from soils across inland waters towards the ocean has been intensified due to anthropogenic perturbations and has significant influence on the anthropogenic C budget and the terrestrial C - sink. However, Earth System Models (ESM) which are used to simulate the terrestrial C sink at global scale still ignore these lateral fluxes. - - 2018-06-30, ongoing project - - - 2016-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - C-LEAK - - - H2020-MSCA-IF-2015 - - - 703813 - - - - - UNIVERSITA DEGLI STUDI DI VERONA - - - EUR 180 277,20 - - - A computer-aided study of the Luwian (morpho-)syntax - - - EUR 180 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - The present project aims at analysing the morpho-syntactical features of the Luwian language working on the available texts and combining a standard linguistic analysis with the implementation of a statistical analysis of the - annotated corpus. By glossing the morpho-syntactical structure of a large selection of both cuneiform and hieroglyphic inscriptions using a protocol derived from and compatible with the Penn Treebank Project and the Leiden Glossing Rules, the - research will proceed by isolating, mapping and modelling the regular as well as the anomalous features of the morpho-syntax of one of the most important and still largely unexplored languages of the ancient Anatolian branch of Indo-European. The - analysis will also identify and focus on the co-dependant syntactical, morphological, semantic and stylistic phenomena present in the corpus (e.g. syntactic triggering of stylistic features, dislocations, topicalisations). The results of the present - research will provide the world of the Indo-European studies with the first comprehensive study ever dedicated to morpho-syntax of the Luwian language. - - 2017-05-31, closed project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - SLUW - - - H2020-MSCA-IF-2014 - - - 655954 - - - - - THE UNIVERSITY OF EXETER - THE UNIVERSITY OF EXETER - - - EUR 1 648 265 - - - Imaging the Dynamical Imprints of Planet Formation in Protoplanetary Discs - - - EUR 1 648 265 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The gas and dust discs around young stars are thought to be the birthplace of planetary systems and are a key area to study if further progress is to be made on understanding the history of our solar system and our own - origins. Once planets have formed in these discs, they dynamically sculpt their environment, for instance by opening tidally-cleared gaps or triggering spiral arms and disc warps. The late stages of this process are likely observed in the - “transitional” discs, where regions spanning tens of astronomical units (AU) have been cleared. The aim of this project is to image the planet formation signatures both during the transitional disc and the earlier T Tauri or Herbig Ae/Be stars phase, - where the protoplanetary bodies are just starting to carve gaps in the optically thick disc. For this purpose, we will employ the latest generation of near-infrared, mid-infrared, and sub-millimeter interferometric instruments that will allow us to - trace a wide range of stellocentric radii, disc scale heights, and dust opacities. We will make use of recent revolutionary advancements in infrared detector technology and equip the CHARA/MIRC 6-telescope beam combiner with a low-read noise camera - that will significantly increase the sensitivity of this instrument and enable us to image protoplanetary discs with 2.5 times higher resolution and much higher efficiency than ever before. These quick-look imaging capabilities will enable us to - trace time-variable structures in the inner few AU and to investigate their relation to the commonly observed photometric and spectroscopic variability. Our interferometric observations in spectral lines aim to detect the accretion signatures of the - young protoplanets themselves. Employing sophisticated radiation hydrodynamics simulations we will achieve an unprecedented global view on protoplanetary disc structure and obtain fundamentally new constraints on theoretical models of planet - formation, planet-disc interaction, and disc evolution. - - 2020-06-30, ongoing project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - ImagePlanetFormDiscs - - - ERC-2014-STG - - - 639889 - - - - - THE UNIVERSITY OF EXETER - - - EUR 183 454,80 - - - People under Pressure: Settlement Abandonment and Human Responses to Environmental and Socio-Economic Stress during the Medieval and Post-Medieval Periods - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The ABANDONMENT project explores the pan-European phenomenon of settlement desertion and shrinkage, which occurred especially during the 14th and 17th centuries. Despite considerable attention being paid to this particularly - rich aspect of archaeological records (within several disciplines), the process of abandonment still remains poorly understood. The project aims to explore how rural communities and the settlements they lived in responded to socio-economic and - environmental stress. The specific objectives are: (a) to determine the processes of settlement shrinkage and abandonment across England; (b) to contextualise changes in settlement patterns within wider transformations of land-use within distinct - regions in the longue durée perspective; (c) to explore the cultural and environmental context of settlement evolution (and extinction) across northern and central Europe to determine the impact of these factors on communities. - - - 2017-12-31, closed project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ABANDONMENT - - - H2020-MSCA-IF-2014 - - - 656650 - - - - - SMARTLY: NATIVES OF SMART LIVING SRL - SMARTLY: NATIVES OF SMART LIVING SRL - UNIVERSITA DEGLI STUDI DELL'AQUILA - - - EUR 150 000 - - - MobIle health-Care system for monitoring toxicity and symptoms in cAncer patients ReceivingdiseasE-oriented therapy - - - EUR 150 000 - - - Italy - Italy - Italy - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - The project aims at developing a pre-commercial solution, till preparing its entrance to the market, of a new cost-effective mobile system for technology-aided home treatment with oral drugs in cancer patients. This project - stems from the ERC Starting Grant VISION, which demonstrated the effectiveness of model-driven approaches for adaptive context-aware resource configuration in internetworking smart objects and wireless multimedia sensor networks. Pervasiveness and - easiness of usage that internetworking smart objects may offer to cancer patients in their everyday life, constitute the baseline of the iCARE system. - - - 2017-11-30, closed project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2015 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Italy - - - iCARE - - - ERC-2015-PoC - - - 693680 - - - - - Institute of Science and Technology Austria - - - EUR 166 156,80 - - - Rate of Adaptation in a Changing Environment - - - EUR 166 156,80 - - - Austria - - - Higher or Secondary Education Establishments - - For thousands of years, we have been changing the environment that surrounds us to satisfy our needs and to make our life safer, easier and more prosperous. However, we are not alone on this planet and the increasing magnitude - of alterations we impose on our environment impacts the biosphere at every level, from bacteria to mammals. Many of these anthropogenic influences may be fatal for those species, leading to extinction and decrease of biodiversity. To avoid that, it - is crucial to understand the process of adaptation in the context of a changing environment, and to understand the limits to population persistence. - - 2018-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Austria - - - RACE - - - H2020-MSCA-IF-2015 - - - 704172 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 195 454,80 - - - Sanskrit Śaiva Intellectuals in the Empire: Innovations, Textual Practices and Religious Interactions in the Late Vijayanagara Period - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - This project entitled ‘‘Sanskrit Śaiva Intellectuals in the Empire: Innovations, Textual Practices and Religious Interactions in the Late Vijayanagara period’’ examines the transformative role of Sanskrit Śaiva intellectuals - in reshaping the religious landscape of South India during the late Vijayanagara period, i.e., from the mid-fifteenth century to the end of the sixteenth century. It is intended to be the first in-depth study of the intellectual history of two - influential Śaiva schools of philosophical theology―Śivādvaita Vedānta and Vīraśaivism―on the basis of a rigorous philological and contextual analysis of selected Sanskrit and vernacular textual sources as well as epigraphic material. The evidence - will be discussed in terms of the schools’ major doctrinal and philosophical positions, textual practices, as well as mutual influences and interactions with other religious groups. The aims of this project are: 1) to assess the impact of Sanskrit - Śaiva intellectuals on the broader intellectual and religious world of the late Vijayanagara period, and their relation to the Vijayanagara royal court; and 2) to shed new light on the complex relationships between the various religious groups active - during the last decades of the empire, in a context of increasing sectarian debates and dramatic socio-cultural transformations. The project will be carried out at the University of Oxford, one of the most renowned centres in Europe for the study of - late medieval and early modern Sanskrit intellectual history. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SSIIE - - - H2020-MSCA-IF-2015 - - - 702470 - - - - - UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA - THE UNIVERSITY OF EXETER - ITA-SUOMEN YLIOPISTO - HASKOLI ISLANDS - CONSIGLIO NAZIONALE DELLE RICERCHE - - - EUR 1 003 500 - - - Collective Excitations in Advanced Nanostructures - - - EUR 1 003 500 - - - Italy - United Kingdom - Finland - Iceland - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - This project aims to develop, fabricate, theoretically and experimentally study carbon based nano-circuits which are able to generate, detect and process broadband electromagnetic (EM) signals. The carbon nanoscale EM sources - can be based, in particular, on Cherenkov radiation emerging when electrons move inside carbon nanotubes (CNTs) or between spatially separated graphene sheets. The frequency of the Cherenkov radiation depends on the CNT radius and chirality or on the - distance between graphene sheets. The performance of carbon EM nano-emitters is determined by the electron momentum relaxation time, which can be determined by measuring the generated THz and microwave fields. The frequency of the emitted EM - radiation can be tuned by acoustic waves that provide distributed feedback for the EM wave. As well, the effects originating from strong coupling between material excitations in carbon-based structures and confined optical modes of microcavities will - be investigated. The formation of polariton modes and their collective properties will be analyzed theoretically. Another set of problems to be considered in the proposed research is associated with the quantum mechanics and quantum optics of - carbon-based nanostructures. We will look at excitonic and plasmonic collective effects in CNTs (especially narrow-band quasi-metallic ones, where excitonic effects are largely overlooked) and in few-layer planar Weyl materials such as graphene, - silicene and germanene. We will also study collective photonics phenomena stemming from the quantum nature of light and look at sophisticated arrangements of carbon-based and other nanostructures in arrays or placing them in microcavities, thus - utilizing the significant expertise of some of the participating groups in quantum optics aiming eventually at a design and feasibility study of novel advance-nanostructure-based optoelectronic devices including microwave, terahertz and light - generators, detectors and frequency modulators. - - 2019-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Italy - - - CoExAN - - - H2020-MSCA-RISE-2014 - - - 644076 - - - - - UNIVERSITA DEGLI STUDI DI VERONA - UNIVERSITA DEGLI STUDI DI VERONA - - - EUR 150 000 - - - Immunomodulatory effects of sustained pantethine release in inflammatory diseases - - - EUR 150 000 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Auto-immune diseases such as multiple sclerosis (MS) and rheumatoid arthritis (RA) and inflammation-associated brain diseases including Alzheimer's disease (AD) globally make up a €45B market and cost society close to €648B. - The huge number of patients with these diseases causes an enormous socioeconomic burden. Currently, MS, AD and RA affect 120M people worldwide. There is no cure for AD and treatments for autoimmune diseases are not fully effective and reducing the - inflammatory component in these diseases is a key strategy. - - 2017-07-31, closed project - - - 2016-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2015 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Italy - - - IMPEDE - - - ERC-2015-PoC - - - 693606 - - - - - UNIVERSITAET INNSBRUCK - UNIVERSITAT POLITECNICA DE VALENCIA - UNIVERSITY COLLEGE LONDON - "NATIONAL CENTER FOR SCIENTIFIC RESEARCH ""DEMOKRITOS""" - TECHNISCHE UNIVERSITAET WIEN - KANSALLISARKISTO - UNIVERSITY OF LONDON - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - UNIVERSITAET ROSTOCK - XEROX - DIREKTION DER JUSTIZ UND DES INNERN - UNIVERSITAET LEIPZIG - DIOZESE PASSAU - DEMOCRITUS UNIVERSITY OF THRACE - - - EUR 8 220 714,50 - - - Recognition and Enrichment of Archival Documents - - - EUR 8 220 716,01 - - - Austria - Spain - United Kingdom - Greece - Austria - Finland - United Kingdom - Switzerland - Germany - France - Switzerland - Germany - Germany - Greece - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - - "The overall objective of READ is to implement a Virtual Research Environment where archivists, humanities scholars, computer scientists and volunteers are collaborating with the ultimate goal of boosting research, innovation, - development and usage of cutting edge technology for the automated recognition, transcription, indexing and enrichment of handwritten archival documents. This Virtual Research Environment will not be built from the ground up, but will benefit from - research, tools, data and resources generated in multiple national and EU funded research and development projects and provide a basis for sustaining the network and the technology in the future. This ICT based e-infrastructure will address the - Societal Challenge mentioned in Europe in a Changing World namely the "transmission of European cultural heritage" and the "uses of the past" as one of the core requirements of a reflective society. Based on research and innovation enabled by the - READ Virtual Research Environment we will be able to explore and access hundreds of kilometres of archival documents via full-text search and therefore be able to open up one of the last hidden treasures of Europe's rich cultural hertitage." - - 2019-06-30, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.3."> - - - EINFRA-9-2015 - e-Infrastructures for virtual research environments (VRE) - - - RIA - Research and Innovation action - - - Austria - - - READ - - - H2020-EINFRA-2015-1 - - - 674943 - - - - - ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON - UNIVERSITAT POLITECNICA DE CATALUNYA - WEST AQUILA SRL - ADAPT IT AE - UNIVERSITA DEGLI STUDI DELL'AQUILA - IQUADRAT INFORMATICA SL - ADAPTERA TECHNOLOGIKES LYSEIS VELTISTOPIISIS EFARMOGON YPODOMON PLIROFORIKES KAI TILEPIKINONION MONOPROSPI IKE - - - EUR 1 080 000 - - - User-centric Middleware Architecture for Advanced Service Provisioning in Future Networks - - - EUR 1 080 000 - - - Greece - Spain - Italy - Greece - Italy - Spain - Greece - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The current paradigm in service provisioning to future communication networks lacks thorough end-to-end interpretation from the quality viewpoint, while the end-users’/customers’ profiles and preferences are mostly not taken - into account. The subjective perception of a provided service, known as Quality of Experience (QoE), is one of the most important factors for a user’s decision on retaining the service or giving it up, and the key parameter for enabling advanced - customer experience management (CEM). The main objective of CASPER is to combine academic and industrial forces towards leveraging the expected benefits of QoE exploitation in future networks. In particular, CASPER will exploit the most recent - approaches in communication networks, such as the Software Defined Networking (SDN) and the Network Functions Virtualisation (NFV), to design and implement a middleware architecture for QoE-driven service provisioning. The architecture will consist - of three interlinked modules, one-to-one mapped to the three instrumental functionalities required for the beneficial exploitation of QoE: i) reliable, secure and passive QoE monitoring, ii) efficient, dynamic and objective QoE estimation, and iii) - robust and real-time QoE-driven service management. The three modules will be optimised and released as an integrated solution, in order to accelerate the adoption of QoE-driven network service management. The cornerstone of this effort will be a - carefully-planned inter-sectorial secondment programme for Experienced Researchers (ERs) and Early Stage Researchers (ESRs). Under this programme, CASPER is expected to foster the exchange of knowledge and strengthen the collaboration among academia - and industry through a bidirectional knowledge-sharing approach, where the academic beneficiaries will contribute by conveying their knowledge in QoE analysis and modelling, while industrial beneficiaries will provide their expertise in service - development and software implementation. - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Greece - - - CASPER - - - H2020-MSCA-RISE-2014 - - - 645393 - - - - - UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA - GOETEBORGS UNIVERSITET - Xtal Concepts GmbH - INSTALLATION EUROPEENNE DE RAYONNEMENT SYNCHROTRON - UNIVERSITAET HAMBURG - LUNDS UNIVERSITET - MOLIROM SRL - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - ASTRAZENECA AB - - - EUR 2 331 284,76 - - - Advanced XFEL and Synchrotron based Probes of Protein Structure and Dynamics - - - EUR 2 331 284,76 - - - Italy - Sweden - Germany - France - Germany - Sweden - Italy - France - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - This cross-disciplinary Marie Curie Innovative Training Network builds upon the transformative opportunities created by existing X-ray sources and new sources soon to be operative in Europe. These opportunities include using - ultrafast X-ray sources to extract time-dependent structural information from proteins; and revolutionary possibilities created by X-ray Free Electron Laser radiation for an entirely new regime of pre-damage serial femtosecond crystallography. No lag - should exist between building new sources and training the next generation of scientists well versed in using these facilities. Our research training will yield new scientific insights on fundamental properties of protein structure and dynamics: one - of the most challenging problems in structural biology; and technological advancements in diverse fields from pharmacology to nanotechnology. - - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Italy - - - X-probe - - - H2020-MSCA-ITN-2014 - - - 637295 - - - - - CONSIGLIO NAZIONALE DELLE RICERCHE - GEIE ERCIM - ENGINEERING - INGEGNERIA INFORMATICA SPA - ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON - FOOD AND AGRICULTURE ORGANIZATION OF THE UNITED NATIONS FAO - International Council for the Exploration of the Sea - INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - TRUST-IT SERVICES LIMITED - OLOKLIROMENA PLIROFORIAKA SISTIMATA - COMMUNICATION & INFORMATION TECHNOLOGIES EXPERTS ANONYMOS ETAIREIA SYMVOULEFTIKON KAI ANAPTYXIAKON YPIRESION - COLLECTE LOCALISATION SATELLITES SA - STIFTELSEN GRID ARENDAL - ASSOCIATION POLE MER BRETAGNE - - - EUR 5 295 753,75 - - - Building Research environments for fostering Innovation, Decision making, Governance and Education to support Blue growth - - - EUR 5 295 753,75 - - - Italy - France - Italy - Greece - Italy - Denmark - France - Greece - United Kingdom - Greece - Greece - France - Norway - France - - - Research Organisations - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Research Organisations - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - - BlueBRIDGE responds to the Juncker Investment Plan opening funding opportunities for e-Infrastructures, innovating current practices in producing & delivering scientific knowledge advice to competent authorities & - enlarges the spectrum of growth opportunities in distinctive Blue Growth areas. - - - 2018-02-28, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.3."> - - - EINFRA-9-2015 - e-Infrastructures for virtual research environments (VRE) - - - RIA - Research and Innovation action - - - Italy - - - BlueBRIDGE - - - H2020-EINFRA-2015-1 - - - 675680 - - - - - UNIWERSYTET IM. ADAMA MICKIEWICZA W POZNANIU - THE UNIVERSITY OF EXETER - UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA - INSTYTUT FIZYKI MOLEKULARNEJ POLSKIEJ AKADEMII NAUK - - - EUR 697 500 - - - MagIC – Magnonics, Interactions and Complexity: a multifunctional aspects of spin wave dynamics - - - EUR 756 000 - - - Poland - United Kingdom - Spain - Poland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The artificial patterning of nanoscale structures provides an excellent opportunity for modifying spectra of their excitations, and therefore for designing materials with unforeseen properties. Newly created materials - (photonic, magnonic or plasmonic) serve as promising candidates for technological applications in integrated devices with smart functionalities for optoelectronic applications, nanoscale thermal transport control, charge free storage and manipulation - of information. Magnetic materials with periodically modulated properties, magnonic crystals (MCs) offer two main distinctive features from which the technology can benefit. Firstly, MCs facilitate tunable excitation spectra controlled via magnetic - field. Secondly, being non-volatile materials they facilitate exploitation of the re-programmable properties. Hence, significant international research effort in MagIC is now devoted to the area of magnonics and its cross disciplinary opportunities - with photonics, phononics and electronics. The frontiers of new ideas, pushing the limits of knowledge, will be developed. The most prominent directions of research are the exploration of nonlinear effects in MCs, tailoring effective damping, - developing theoretical models of the spin wave scattering in nanoscale, investigating effects of the broken periodicity and fractal structures on magnonic spectra. Moreover, MagIC will exploit still unexplored directions of mutual coexistence of - magnonic functionalities with these of photonic, plasmonic or phononic in a single nanostructure. The academic exchange (168 months of visits in 4 years) supplemented with abundant network and outreach activities will aim to continue existing - collaboration, establishing new links, supporting multilateral transfer of knowledge and expertise among seven European and Ukraine research teams, striving to advance the aforementioned research fields, development of innovation and career for - research and innovation staff members. - - 2019-01-31, ongoing project | - - - 2015-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Poland - - - MagIC - - - H2020-MSCA-RISE-2014 - - - 644348 - - - - - ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOMATERIALES- CIC biomaGUNE - AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH - UNIVERSITAET LEIPZIG - UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6 - UNIVERSITY OF MICHIGAN THE REGENTS OF THE UNIVERSITY OF MICHIGAN - Yerevan State University - COMISION NACIONAL DE ENERGIA ATOMICA - CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TECNICAS (CONICET) - UNIVERSIDAD NACIONAL DE GENERAL SAN MARTIN - - - EUR 1 219 500 - - - Hybrid Drug Delivery Systems upon Mesoporous Materials, Self Assembled Therapeutics and Virosomes - - - EUR 1 219 500 - - - Spain - Austria - Germany - France - United States - Armenia - Argentina - Argentina - Argentina - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - - HYMADE focuses on the development of capsules and engineered colloidal particles for drug delivery combining mesoporous colloids, the Layer by Layer (LbL) technique and virosomes. The capsules and particles have potential - applications in cancer and inflammatory diseases such as rheumatoid arthritis and uveitis. - - - 2019-01-31, ongoing project - - - 2015-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Spain - - - HYMADE - - - H2020-MSCA-RISE-2014 - - - 645686 - - - - - DANMARKS TEKNISKE UNIVERSITET - LUNDS UNIVERSITET - THE UNIVERSITY OF EXETER - FORSCHUNGSVERBUND BERLIN EV - HUMBOLDT-UNIVERSITAET ZU BERLIN - FUNDACIO INSTITUT DE CIENCIES FOTONIQUES - NKT PHOTONICS A/S - RADIANT LIGHT SL - - - EUR 4 001 129,28 - - - Infrared sensing made visible: Combining infrared light sources and upconversion sensors for improved sensitivity in medical applications and gas analysis - - - EUR 4 001 129,28 - - - Denmark - Sweden - United Kingdom - Germany - Germany - Spain - Denmark - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The mid-infrared (mid-IR) wavelength range is an emerging and important new topic for frontier research. Its general importance relates to a multitude of mid-IR industrial and biomedical sensor applications. Chemical finger - prints of most complex molecules such as those found in food, tissue or catalytic compounds all have vibrational spectra in the mid-IR, thus identifiable through mid-IR spectroscopy. Incidentally also the fundamental absorption bands of gas molecules - are located in the mid-IR enabling novel instrumentation for mid-IR gas spectroscopy at small concentrations relevant for applications like, “leak-tests” or remote sensing of greenhouse gases. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Denmark - - - Mid-TECH - - - H2020-MSCA-ITN-2014 - - - 642661 - - - - - QUEEN MARY UNIVERSITY OF LONDON - - - EUR 183 454,80 - - - Comparative genomics of sugar-eating bats: Implications for the genetics of glucose metabolism and diabetes - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Diabetes and impaired glucose tolerance are major threats to human health. These conditions are linked to obesity and poor diet but also have major genetic components. To date, most knowledge of the genetics of sugar - metabolism and diabetes comes from epidemiological studies of humans and lab studies of mice. However, novel powerful insights might also be obtained by studying novel non-model species that have undergone evolutionary adaptations for subsisting on - high sugar diets. Among mammals, bats are unique in their range of dietary specialisations with up to eight lineages having independently evolved nectar-feeding (‘nectarivory’). Yet how these bats are able to survive on high sugar diets, and regulate - their blood sugar to resist the damaging effects of glucose toxicity, is not understood. To discover the genes and mutations that confer these abilities in bats, we will use state-of-the-art cross-species targeted genome-capture to obtain thousands - of orthologous sequences from all nectar-feeding fruit bats and their non-nectar feeding relatives. We will first identify genes showing signatures of molecular adaptation for each key branch associated with the acquisition of nectar feeding. Second, - we will compare these sets of genes, and their respective protein-protein interaction networks, to determine whether divergent bats have evolved nectarivory by recruiting the same genes and pathways. Our findings will improve our understanding of how - natural selection has driven dietary specialisation in mammals, and will also shed light on whether related metabolic diseases arise via mutations occurring at the same sites, or instead arise from the disruption of more evolutionarily conserved - sites that have not been subject to molecular adaptation. - - 2019-06-04, ongoing project - - - 2017-06-05 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - CHIROGLU - - - H2020-MSCA-IF-2016 - - - 753367 - - - - - Centrum Fizyki Teoretycznej Polskiej Akademii Nauk - - - EUR 146 462,40 - - - Dance of galaxies: testing General Relativity and alternatives using galaxy velocity fields - - - EUR 146 462,40 - - - Poland - - - Research Organisations - - We propose to use information encoded in peculiar velocity statistics of galaxies in the Local Universe as well as observed redshift space distortions (RSD) of distant galaxies for rendering new and very precise constraints on - the validity of General Relativity (GR) and competing theories of modified gravity (MG) on cosmological and intergalactic scales. - - 2019-09-03, ongoing project - - - 2017-09-04 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Poland - - - GalaxyDance - - - H2020-MSCA-IF-2016 - - - 748525 - - - - - TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY - - - EUR 182 509,20 - - - Role of a novel proteasome-associated DUB – A boon for therapeutics - - - EUR 182 509,20 - - - Israel - - - Higher or Secondary Education Establishments - - Clearing-up old or redundant proteins is essential for cells to live; this job is largely done by 26S Proteasome. The multisubunit complex – 26S Proteasome – is extraordinarily conserved throughout all eukaryotic phyla, in - terms of subunit composition and overall structure. However, in preparation of this research proposal, the Researcher found a novel association of 26S proteasome with a clinically important deubiquitinating enzyme (DUB), USP9X. In a subset of - proteasome purified from human tissue by the Researcher, USP9X was in fact the major DUB replacing commonly reported enzymes (USP14, UCH-L5). This finding shatters the notion of proteasome as a static, fixed, complex, and opens up the search for - expanded spheres of interaction. - - 2019-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Israel - - - DUBs26S - - - H2020-MSCA-IF-2016 - - - 748804 - - - - - TECHNISCHE UNIVERSITEIT EINDHOVEN - UNIVERSITAET LEIPZIG - JANSSEN CILAG SA - UNIVERSIDAD DE CORDOBA - THALESNANO NANOTECHNOLOGIAI KUTATO-FEJLESZTO ZRT - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - KATHOLIEKE UNIVERSITEIT LEUVEN - - - EUR 2 248 434,36 - - - Accelerating photoredox catalysis in continuous-flow systems - - - EUR 2 248 434,36 - - - Netherlands - Germany - Spain - Spain - Hungary - France - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - - The use of visible light energy to induce chemical transformations constitutes an interesting and green activation mode of organic molecules. However, implementation of this energy source in organic synthetic methodologies and - in the industrial production of fine chemicals has been challenging. The Photo4Future Innovative Training Network establishes a training network with five beneficiaries from academia and five beneficiaries from industry to tackle the challenges - associated with photochemistry in a coherent and comprehensive fashion. In total 13 Early Stage Researchers will be recruited within the Photo4Future network. The network will provide them with opportunities to undertake research with the aim to - overcome the current limitations towards the applicability and scalability of photochemical transformations. This will be achieved through a rational design of novel photocatalytic methodologies, improved catalytic systems and innovative - photoreactors. Furthermore, the ESRs will be trained in the Photo4Future graduate school, covering training in scientific, personal and complementary skills. All the ESRs will perform two secondments, of which at least one is carried out with an - industrial partner. Consequently, the ESRs will have improved career prospects and a higher employability. Due to the high degree of industrial participation, the Photo4Future network will provide an innovation-friendly environment where scientific - results can grow and become products or services that will benefit European economies. - - 2018-12-31, ongoing project | - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Netherlands - - - Photo4Future - - - H2020-MSCA-ITN-2014 - - - 641861 - - - - - EUROPEAN X-RAY FREE-ELECTRON LASERFACILITY GMBH - STIFTUNG DEUTSCHES ELEKTRONEN-SYNCHROTRON DESY - ELETTRA - SINCROTRONE TRIESTE SCPA - ASSOCIATION INTERNATIONALE EXTREME-LIGHT-INFRASTRUCTURE DELIVERY CONSORTIUM - INSTALLATION EUROPEENNE DE RAYONNEMENT SYNCHROTRON - HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF EV - LUNDS UNIVERSITET - PAUL SCHERRER INSTITUT - - - EUR 7 000 000 - - - European Cluster of Advanced Laser Light Sources - - - EUR 7 466 800 - - - Germany - Germany - Italy - Belgium - France - Germany - Sweden - Switzerland - - - Research Organisations - Research Organisations - Research Organisations - Other - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - - Advanced optical laser light sources and accelerator-based X-ray sources, as well as their technologies, scientific applications, and user communities, have developed independently over more than five decades. Driven by the - developments at each optical laser and free-electron laser research infrastructures (RIs) in recent years, the gap between the optical laser and accelerator-driven light sources has diminished significantly. Both communities operate, implement, or - plan advanced laser light source RIs, combining high-power optical and high-brightness X-ray light sources operated as dedicated user facilities. Operational and technical problems of these RIs have become very similar, if not identical. In specific - cases, joint projects by the two communities have been initiated, but a closer and more structured collaboration of the corresponding communities and light sources is urgently required and shall be developed through this project. - - 2018-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-4-2014-2015 - Implementation and operation of cross-cutting services and solutions for clusters of ESFRI and other relevant research infrastructure initiatives - - - RIA - Research and Innovation action - - - Germany - - - EUCALL - - - H2020-INFRADEV-1-2014-1 - - - 654220 - - - - - THE UNIVERSITY OF EXETER - - - EUR 255 349,80 - - - Ecological and evolutionary forces shaping microbial diversity in freshwater blooms - - - EUR 255 349,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - "Bacterial communities dominate the living biomass on Earth and contribute significantly to all global cycles of matter and energy. However, due to the high genetic heterogeneity of the ecosystems and their richness in diverse - microbial species, our knowledge of bacterial communities remains limited. Therefore, in order to understand any bacterial community's ecology and predict how these communities and their respective ecosystems will respond to environmental changes, we - need (i) to identify the different ecologically distinct microbial populations (or ""clusters"") that compose it, and (ii) to determine the interactions between clusters, and how they evolve. To address these challenging goals, this study will use - the model system of Microcystis, the cyanobacterium that is mainly responsible for toxic algal bloom in lakes worldwide. The goal of this project is to (i) determine how (and if) Microcystis is specialized into different ecologically and genetically - distinct clusters, (ii) to track how the Microcystis populations (or clusters) respond to environmental changes (pH, temperature, pollution from fertilizer runoff) and biological factors (viruses that prey on bacteria). This will allow us to - understand how Microcystis populations change and adapt over time, helping us to predict and prevent harmful blooms. Using a unique multidisciplinary approach mixing ecology and evolution, and combining observations from natural time-courses in - lakes, in situ experiments in microcosms within lakes, and in vitro experiments, this project will provide an unprecedented understanding of how changing regimes of natural selection, imposed by environmental and biological factors, shape microbial - communities on the scales of populations, genomes and genes. This project will provide major advances in bloom understanding, in prediction by the identification new genetic biomarkers and in prevention by defining the conditions under which phage - therapy might be a practical strategy." - - 2018-05-31, ongoing project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - MicroEcoEvol - - - H2020-MSCA-IF-2014 - - - 656647 - - - - - MBN RESEARCH CENTER GGMBH - UNIVERSITA DEGLI STUDI DI FERRARA - JOHANNES GUTENBERG-UNIVERSITAT MAINZ - AARHUS UNIVERSITET - THE OPEN UNIVERSITY - UNIVERSITE PAUL SABATIER TOULOUSE III - INSTALLATION EUROPEENNE DE RAYONNEMENT SYNCHROTRON - ISTITUTO NAZIONALE DI FISICA NUCLEARE - - - EUR 693 000 - - - Periodically bent crystals for crystalline undulators - - - EUR 693 000 - - - Germany - Italy - Germany - Denmark - United Kingdom - France - France - Italy - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - - The PEARL project aims at advancing the technologies for manufacturing of high quality Periodically Bent Crystals (PBCr). The PBCr developed in the course of this project will be utilised for the construction of novel light - sources of high-energy (hν≥102 keV up to GeV range) monochromatic electromagnetic radiation by means of a Crystalline Undulator (CU) [1]. The technological and experimental part of this project will be accompanied by the complimentary advanced - theoretical research utilising modern theoretical, computational and modelling methods accomplished with high performance computing techniques. A broad interdisciplinary, international collaboration has been created in the frame of FP7 PIRSES-CUTE - project, which was focused on initial experimental tests of the CU idea and the related theory, for review see [1]. This project has been successfully completed in March 2015 and left the matter experimentally validated to a degree that is - tantalising, requiring further experimentation. In particular CUTE elucidated the demand on manufacturing PBCrs of an exceptional lattice quality, their experimental characterisation and exposure against the high quality beams of ultra-relativistic - electrons and positrons for the observation of the strong coherent effects in the photon emission process. PEARL will focus on solving the whole complex of the important technological, experimental and theoretical problems aiming to achieve the major - breakthrough in this important research area. The PEARL international collaboration is extended with respect to CUTE and involves the new partners with the essential, necessary, complementary expertise and experimental facilities. The PEARL research - programme is highly collaborative and requiring numerous exchange visits between the involved laboratories, joint workshops and conferences. Therefore, RISE type of project is the most suitable for strengthening of this very essential, ongoing, - international collaborative research. - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Germany - - - PEARL - - - H2020-MSCA-RISE-2015 - - - 690991 - - - - - UNIVERSITETET I TROMSOE - - - EUR 196 400,40 - - - Disentangling variation: A crosslinguistic investigation of bilingualism and non-standardization - - - EUR 196 400,40 - - - Norway - - - Higher or Secondary Education Establishments - - This project will investigate the ways in which variation in the linguistic input affects the trajectory of language development and its final outcome. This exploration of language variation and its contributing factors will - bring together both the sociolinguistic and the neurocognitive aspects of the human ability to use language, through adopting a cross-linguistic perspective. Acceptability judgment tasks will be the vehicle to test different domains of grammar, such - as word-order patterns, adjective orderings, and grammatical illusions, across different linguistic communities in Scandinavia, Cyprus, and Greece. Through examining acceptability judgments in neurotypical adult populations, this project will foster - a novel, three-way comparison across (i) monolingual, bilingual, and bilectal speakers, (ii) three domains of grammar, (iii) varying developmental trajectories within the bilingual population, including heritage language learners and L1 attriters. - The combination of on-line and off-line measures will shed light on how different domains of grammar are processed by the monolingual and bilingual mind and elucidate whether some or all types of bilingualism confer a cognitive advantage in this - processing. Two key objectives of this project are the investigation of both standard and non-standard varieties and the promotion of linguistic diversity. Ultimately, the findings of this project will generate substantive, empirically informed - hypotheses about human language and the bilingual mind. Within the present context of increased multilingualism throughout the lifespan these results are likely to achieve a marked scientific impact. - - 2019-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Norway - - - DIVA - - - H2020-MSCA-IF-2016 - - - 746652 - - - - - THE UNIVERSITY OF EXETER - - - EUR 195 454,80 - - - Multimedia Communication and Processing over Vehicular Cloud Networks for AutonomousDriving - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Autonomous driving technologies have recently drawn enormous research attention. It is predicted that autonomous driving will become the most promising form of future Intelligent Transportation Systems (ITS) and will gradually - gain market traction in the coming decade. Although several automobile manufacturers have recently demonstrated prototypes, a great number of technical challenges should be addressed in order to reap the full potential of autonomous driving. This - project aims to pioneer a framework that leverages innovative multimedia communication and processing technologies for efficient sensor data exchange in order to support autonomous driving application over vehicular cloud networks (VCNs). The project - is unique in its ground-breaking integration of two challenging technical aspects over VCNs: multimedia-driven vehicular wireless communications and network-aware adaptive multimedia processing. The interaction and mutual promotion between these two - aspects will enable each to design more efficient operational procedure and protocols. - - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - MACROSS - - - H2020-MSCA-IF-2016 - - - 752979 - - - - - THE QUEEN'S UNIVERSITY OF BELFAST - - - EUR 195 454,80 - - - Shakespeare and Indian Cinematic Traditions - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Current work on Shakespeare and India has largely ignored the cinematic idiom. Working with acknowledged expert in global Shakespeare, Professor Mark Thornton Burnett (MTB) of Queen’s University Belfast (QUB), experienced - researcher, Dr Rosa María García Periago (RMGP), will undertake a fellowship that comprehensively examines for the first time the role of Shakespeare in Indian cinemas, with a focus on regionalism, diversity, locality and gender. Rather than simply - engaging with ‘Bollywood’, the fellowship will direct attention to the variety of expressions of Shakespeare in different Indian film industries, languages and diasporic contexts, the majority of which have been critically neglected. Academic outputs - include a project website with database, a journal article, and a co-edited volume. Integrally important to the fellowship’s recovery mission is the centrality of women not only as subjects of representation but also as filmmakers and creative - practitioners. Bringing together critical and practice-based enquiries, the fellowship includes two secondments with relevant arts organizations. These practice-led elements complement a sustained intercultural engagement programme, including - public-facing lectures, a workshop/film festival and an exhibition, of benefit to QUB, the city of Belfast and beyond. The fellowship, then, will produce original research while generating local and international impact and supporting the career - development and mobility of the experienced researcher. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ShakespeareIndia - - - H2020-MSCA-IF-2016 - - - 752060 - - - - - THE UNIVERSITY OF EXETER - - - EUR 183 454,80 - - - Female immune function in compensation for polyandry - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The level of polyandry is a key trait influencing population dynamics and inter-sexual interactions of organisms. In nature, females of some species mate only once in their life time, whereas others mate with multiple males. - My research aims at understanding why there is so many variation in the level of polyandry. I will tackle this question by focusing on female immune function. Mating can up-/down-regulate immune function, which is likely to inflict fitness costs on - females if they mate with multiple males. If the level of polyandry positively correlates with the efficiency of female immune function, immune function may compensate for the costs of multiple mating. To test this hypothesis, I will use 25 isolines - of the fruit fly Drosophila pseudoobscura that genetically differ profoundly in their predisposition to polyandry. This unique system will allow me to examine effects of both mating and genetic variation in polyandry on female immune function. This - project will complement my current research that to date has focused on specific applied agricultural-pest systems. I have less experience working on explicitly evolutionary-focused questions, so this research programme will provide an additional - dimension to my applied research. Prof Wedell is a leading scientist in the field of experimental evolutionary biology, and is the perfect person to expand my horizons into more conceptual and broader ideas. Under her mentoring, I will be able to - develop my own research and skills in proposal writing and teaching. The new knowledge, skills and techniques that I will acquire through the project will feed back to my previous work on agricultural pests, which will result in me being able to - bridge the gap between model organism and agricultural pest systems. The unique situation will enable me to develop a unique line of research in both evolutionary and applied biology. Ultimately, this Fellowship will put me in an excellent position - for my further career. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - IMMUNFUNC - - - H2020-MSCA-IF-2016 - - - 746169 - - - - - UNIVERSITAT KONSTANZ - - - EUR 171 460,80 - - - Forcing in Contemporary Philosophy of Set Theory - - - EUR 171 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - Forcing is one of the defining techniques of modern set theory. As of late its extensive and deep mathematical results and related foundational questions gained wider attention in the international debate in the philosophy of - mathematics. This can be witnessed by the recent development of different research programs in the philosophy of set theory like the Multiverse or Hyperuniverse Program and the formation of new platforms for discussion like the newly founded Set - Theoretic Pluralism network. - - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - Philosophy Forcing - - - H2020-MSCA-IF-2016 - - - 752211 - - - - - UNIVERSITA DEGLI STUDI DI PADOVA - - - EUR 180 277,20 - - - Tackling early school leaving and low school performance through working with students’ representational spaces. The case of 15 years old students in France, Italy and Greece. - - - EUR 180 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - The project explores the question of early school leaving and low performance two of the five EU headlines for education in the Horizon 2020 agenda, addressing the wider societal challenge of employment and social inclusion of - young people. The project argues that the theorization of “context” in current state of the art cannot capture the new emerging dynamics caused by globalization and multiple migrations and seeks to establish that students’ “representational spaces” - operationalized through their imagined geographies operate as an unidentified and powerful hidden curriculum affecting their educational trajectories and career choices. Towards this purpose, a three step field research will be conducted in three EU - countries (France, Italy, Greece). First, the representational spaces of 150 15 years old students, of both urban and rural areas, will be explored through questionnaires and visual methodologies. Second, a discourse analysis of the national - education policy documents will be conducted to investigate the responsiveness of national policies to the change of scale (EU, global). Third, focus groups and interviews will be conducted in order to investigate if changing students’ - representational spaces, involves changes in their attitudes towards school and learning. Correlations will be explored and cross-group comparisons will be made to transcend the existing categorization of the state of the art. These objectives will - contribute to the better understanding of students’ educational and life paths under the lens of the current sociopolitical and economic dynamics. - - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - Italy - - - RE-mapping - - - H2020-MSCA-IF-2016 - - - 750405 - - - - - Asociacion - Centro de Investigacion Cooperativa en Nanociencias - CIC NANOGUNE - - - EUR 170 121,60 - - - Proton-Irradiated Ice: Dynamics and Chemistry from First Principles - - - EUR 170 121,60 - - - Spain - - - Research Organisations - - Understanding radiation effects on different materials is of paramount importance for many scientific and technological fields like those related to nuclear energy, space industry, laser- and ion-based materials processing and - therapeutic applications. The particular case of radiation effects on pure and mixed water ice is very important in Astrochemistry and Prebiotic Chemistry, being water ice present in cosmic dust grains and on the surface of many bodies in the Solar - System like asteroids and several satellites (e.g. Europa, Callisto and Ganymede). - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - PROIRICE - - - H2020-MSCA-IF-2016 - - - 748673 - - - - - UNIVERSITA DEGLI STUDI DI VERONA - - - EUR 180 277,20 - - - Currents and Minimizing Networks - - - EUR 180 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - The core of this project is Geometric Measure Theory and, in particular, currents and their interplay with the - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - CuMiN - - - H2020-MSCA-IF-2016 - - - 752018 - - - - - UNIVERSITY OF SURREY - - - EUR 195 454,80 - - - Development of eco-friendly ironmaking processes based onGPU-enhanced DEM-CFD modelling - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Blast furnaces are widely used in the iron-making industry. The running of blast furnaces consumes 60% energy of whole steel industry and is primarily responsible for the CO2 blueprints in steel plants. As the steel industry - is suffering much with the increase iron ore prices and global economy recession in recent years, it has now become a urgent need to adopt innovative approaches to reduce the production cost in iron-making. It is well recognized that the development - of eco-friendly steel plants are urgently demanded. DECRON provides a unique and timely opportunity to bring together the fellow’s research experience in the high performance computing, GPU and discrete element modelling (DEM) with the supervisor’s - extensive experience in coupled DEM with computational fluid dynamics (DEM-CFD), particle flow, packing and segregation. This will result in the development of novel charging methods for blast furnaces based upon a thorough micro-mechanistic - understanding of the process using GPU-enhanced DEM-CFD, and lead to more precision and better controlled charging systems for blast furnaces. DECRON will for the first time devise an indisputable technological innovation and establish feasible - strategies to achieve controlled burden distribution in blast furnaces, which will maximise energy efficiency and reduce CO2 emission in iron-making processes. - - 2019-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - DECRON - - - H2020-MSCA-IF-2016 - - - 747963 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 195 454,80 - - - Capital Accumulation Through Informal Urbanization in India - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Unauthorized development, informal real estate & housing markets and informal settlements, referred to collectively here as 'informal urbanization' (IU), remain durable, and likely expanding, in much of the global South. - IU hampers the implementation of any urban development plan or policy that require land and which require adequate information about land use and above and below ground infrastructure. While much is known about how capital is accumulated and - regulated in sectors of the formal economy, much less is known about how this works in the informal economy and very little is known about how this works in IU sectors. This is due to the assumption, influenced by de Soto's work, that the lack of - formal property rights leads to 'dead capital', i.e., capital that cannot accumulate. This wisdom must be challenged for if IU is a significant domain of accumulation, then policies and politics by planners and lawmakers for sustainable & - inclusive urban development range from inadequacy to lack of fitness for purpose. This Fellowship integrates David Harvey's accumulation theory with Barbara Harriss-White's social structure of accumulation approach to the informal economy to - establish a new strand of research. Fieldwork will occur in two municipalities in India where IU is widespread. The aims are: (1) synthesize the theory & evidence of accumulation via IU and its consequences for urban governance and inclusive - development more generally (2) qualitatively study & record the phenomena in six cases (3) apply cross-case analysis and (4) disseminate findings via journal articles, policy briefs, city reports, roundtables with respondents, curriculum input - & guest lectures. Based at the Contemporary South Asian Studies Program in the School of Interdisciplinary Area Studies at Oxford, with fieldwork in India, the project strengthens my: research networks, research & project management skills - and contributes to fields of urban studies, geography & development studies. - - 2019-09-03, ongoing project - - - 2017-09-04 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - Urban Informality - - - H2020-MSCA-IF-2016 - - - 749814 - - - - - UNIVERSITETET I TROMSOE - - - EUR 208 400,40 - - - Multiple Perspectives on Grammatical Gender in the Bilingual Lexicon - - - EUR 208 400,40 - - - Norway - - - Higher or Secondary Education Establishments - - Grammatical gender represents an important area of research given the difficulty gender assignment and agreement poses to bilinguals at all levels of proficiency. As such, the objective of GenBiLex is to develop a - comprehensive proposal of grammatical gender in the bilingual lexicon that includes psycholinguistic, language acquisition and theoretical linguistic approaches. Little previous research has examined the consequences of differences between the L1 and - L2 gender systems, either in terms of the number of gender values (e.g. 2 vs 3 values) or the values themselves (e.g. common/neuter vs masculine/feminine). GenBiLex addresses this crucial gap by examining bilinguals with different types of gender - systems in order to offer insight into the representation of and interactions between the L1 and L2 gender features in the lexicon and how this is borne out in the use of gender in the L2. - - - 2019-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Norway - - - GenBiLex - - - H2020-MSCA-IF-2016 - - - 748966 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 158 121,60 - - - Batteries based on Calcium: from electrolyte development to full cell proof-of-concept - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - The development of rechargeable batteries based on multivalent cations as charge carriers holds promise of enhanced energy density when compared to single valent ions such as lithium or sodium. Proof-of-concept has been - achieved for magnesium batteries with complex electrolyte compositions but an analogous technology based on calcium ion would hold promise for faster reaction kinetics due to its lower polarizing character and enhanced energy density due to its lower - reduction potential. - - - 2019-05-15, ongoing project - - - 2017-05-16 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - BATCA - - - H2020-MSCA-IF-2016 - - - 743439 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 183 454,80 - - - Catalytic Enantioselective Allene Cycloisomerisation Reactions for Alkaloid Total Synthesis - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - A new catalytic enantioselective cycloisomerisation reaction for the direct creation of the azabicyclic core of strychnos alkaloids is proposed. Strychnos alkaloids have been the subject of intensive investigation over the - last decades. Recently, leuconicines A and B, which are new members of the Strychnos alkaloid family, have been isolated from extracts of the Malaysian plant Leuconotis maingayi. Leuconicines possess significant bioactivity and they potently reverse - multidrug resistance in vincristine-resistant leukemia cells. However, further studies into the biological profile of these natural products are hindered due to insufficient quantities being available from the natural source. In order to secure - sufficient quantities and fully determine the therapeutic potential of the leuconicines, a new source of these target molecules is required. A new synthetic route which develops and incorporates ‘state-of-the-art’ methodologies to rapidly forge the - extremely complex 6,5,5,6,6,6 hexacyclic ring system and 4 stereocenters, will provide the material. Nevertheless, the synthetic routes toward complex natural products are usually long, contain many individual steps and involve manipulations after - each step. For these reasons, new, simple and synthetically efficient organic transformations which reduce the drain of resources are desired. This Fellowship project combines total synthesis, new catalytic enantioselective methodology development, - computational calculations and biological evaluation. It has been designed to augment and complement the research and transferable skills sets of the Marie Curie fellow and will greatly enhance his career prospects accordingly. Through the training - and the research results arising, the Fellowship will be beneficial to the fellow, the host institution and European science. - - 2019-06-11, ongoing project - - - 2017-06-12 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - CATRATS - - - H2020-MSCA-IF-2016 - - - 751281 - - - - - UNIVERSITEIT VAN AMSTERDAM - - - EUR 165 598,80 - - - Conscripted Volunteering: An Ethnographic Study of Community Engagement Schemes in the Israeli Military - - - EUR 165 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Militaries increasingly engage their soldiers in activities framed as ‘community engagement’ or ‘volunteering’, ranging from facilitating activities for children to delivering food to the needy. ‘Conscripted volunteering’, as - I term this phenomenon, is part of a broader ‘moralization’ of contemporary society that glorifies ‘volunteering’ as a prominent route for ethical conduct. Under neoliberalism, ‘volunteering’ becomes an object of intensified political interest and - promotion. While ‘volunteering’ that is facilitated by militaries can be considered as a means to enhance their public legitimacy, inspired by corporate techniques of reputation management, I propose to analyse it also as a governmentality technique - that reinforces the ideological and ethical adherence of soldiers. The proposed research project explores the intensive implementation of ‘conscripted volunteering’ in the Israeli military, a military which is considered a paradigmatic case in - studies of armed forces. - - 2019-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - ConscriptedVolunteer - - - H2020-MSCA-IF-2016 - - - 751924 - - - - - Eidgenössische Technische Hochschule Zürich - - - EUR 187 419,60 - - - Multiscale computational modelling for natural hip biomechanics and tribology - - - EUR 187 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - Hip osteoarthritis (OA) has already affected over 60 million people worldwide, usually causing persistent pain, reduced quality of life and even physical disability to the patients. Currently, the most effective treatment for - end-stage of hip OA is total hip replacement (THR). However, current THR surgery is not as successful in younger patients who have expectation of an active life style compared to aging patients. New generation of treatments such as tissue sparing - substitution treatment and regenerative treatment for early degenerative disease of the hip joint for these more active patients is urgently required. The new generation of treatments, however, require an in-depth knowledge of the functional - biomechanics and tribology of the cartilage in the hip joint. The proposed action, therefore, aims to develop a novel computational method that can simulate the functional performance of natural hip joint for supporting research and development of - new generation of cartilage substitution therapies and regenerative interventions for the early degeneration of hip disorders. The action involves an experienced researcher, Dr Xijin Hua, from the University of Leeds in UK visiting the Institute for - Biomechanics at Swiss Federal Institute of Technology in Zurich, under the supervision of Professor Stephen Ferguson for 24 months to work on the project “Multiscale computational modelling for natural hip biomechanics and tribology” (MSCHIPBIO). The - action also aims to provide a platform for the fellow and the host organisation to share and transfer the knowledge and skills in the field of musculoskeletal biomechanics, advanced finite element simulation methods, computational fluid dynamics and - tissue engineering, for the fellow to gain complementary knowledge and skills, and for the host organisation to broaden the research domains in cartilage substitution and regenerative therapies, and to enhance the leading position in the fields of - computational biomechanics. - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - MSCHIPBIO - - - H2020-MSCA-IF-2016 - - - 745426 - - - - - THE UNIVERSITY OF EXETER - - - EUR 195 454,80 - - - No country for old sperm: male aging, sperm aging, and external stressors as determinants of sperm quality and fertility - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Deterioration in sperm quality with age is a major cause of male infertility. This has particular socio-economic relevance for Europe where fatherhood is increasingly delayed and infertility has reached near epidemic levels, - costing the EU €4 billion per annum. The mechanisms causing, and the full consequences of declining sperm quality with age remain very poorly understood. For example, it is unclear how much of the reduction in sperm quality is due to advanced male - age or the time sperm are stored within males reproductive organs, and we do not understand the mechanisms responsible for deteriorating sperm quality with increasing male age. The general aim of this project is to disentangle the effects of male - aging and sperm aging on sperm quality, fertility and reproductive fitness using Drosophila melanogaster as a model. We will also test putative mechanisms thought to cause age-related fertility declines and test two possible general pathways through - which sperm age. This proposal is a much needed integration of evolutionary ecology and sperm physiology, benefiting from the ideal match of skills and expertise of the Applicant (Tourmente - physiology), and the PI (Hosken - evolution). Since the - mechanisms and phenomena studied are conserved across animals, the research proposed has high potential to produce results relevant to fundamental and applied research in human aging and reproductive health and animal breeding. The MSC fellowship - will be pivotal for Applicants development toward independent research and offers the unique opportunity to work in one of the most prominent evolutionary ecology groups worldwide. The Biosciences Department at the University of Exeter is - world-leading and provides excellent opportunities for the personal career development of the Applicant, who in turn brings novel skills to Exeter that will greatly benefit this group. - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SPERMAGE - - - H2020-MSCA-IF-2016 - - - 749784 - - - - - THE UNIVERSITY OF EXETER - - - EUR 195 454,80 - - - Elucidating continental-scale patterns of bird migration with weather radars - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Migration is a wide-spread phenomenon which allows animals of many different taxa to take advantage of seasonal variation in resource abundance. Radar is a powerful tool to observe and track migratory flights. In this action I - will use the existing European network of weather radars to investigate bird migration behaviour and patterns at the continental-scale in relation to topography, weather and insect migration. A unique aspect of this action is that I will have access - not only to bird migration data from weather radars, but also to complementary data from small-scale dedicated biological radars (units specifically designed to monitor bird and insect migration), as well as bird ringing and monitoring data from - several key locations (migration hotspots). Weather radars will provide data on bird migration patterns at the continental-scale (along the “Western European Flyway”); the small-scale biological radars will provide more detailed information on insect - and bird migration patterns at specific sites; and the ringing and monitoring data will provide species composition at specific points along the flyway. Together this will give us a unique overview of the flux and behaviour of migratory animals - across Europe, something that has never before been possible. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - MigrationRadar - - - H2020-MSCA-IF-2016 - - - 749224 - - - - - UNIVERSITA DEGLI STUDI DI VERONA - - - EUR 180 277,20 - - - Gluten Epitope Molecularly imprinted polymer Sensor - - - EUR 180 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - Introduction-state of art of the problem: The main goal of the present proposal is to devise a chemical sensor capable of gluten detection in food. Gluten is the allergen that triggers autoimmuno reactions in people suffering - of celiac disease (CD). CD is an autoimmune disorder, characterized a variety of genetic assets, which is estimated to affect the 1-2 % of the European population with direct costs on the healthcare estimated as 3 bn Euros/year. According to the - state of the current knowledge gluten-free diet is mandatory in CD. Food shall contain less than 20 mg/kg gluten of to be considered as “gluten-free” and to be eaten safely. - - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - GEMS - - - H2020-MSCA-IF-2016 - - - 752438 - - - - - THE UNIVERSITY OF EXETER - - - EUR 195 454,80 - - - Using charcoals as a proxy to estimate energy released from small Impact cratering processes - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Over the last half a century there has been much debate over the quantities and mechanisms of thermal energy release during impacts of small asteroids such as Tunguska event (Russia) or Kaali craters. This has been caused in a - large part by the fact that the existing observational and modelling approaches have focused on large impact craters that generate high temperature/pressure transitions which leave noticeable signatures in the rocks they affect. However, small - impacts craters developed in unconsolidated materials have not been thought to leave long lasting traces of the thermal energy released during their formation. Recently however, Losiak et al. (2016) found charcoal buried within ejecta blanket of - Kaali Main crater where sedimentological analyses and 14C dating suggest that the charcoal was formed at the same time as the craters within which they were found. Subsequently Losiak identified charcoal in Kaali 2/8, Ilumetsa Small, Ilumetsa Large - and the Morasko Main craters, indicating that charcoal is not restricted to a single crater, single impact or single location. Project ImpCHAR will use a novel analysis method that measures the reflectance properties of charcoal, which has been - recently shown to relate to the energy that created it. ImpCHAR will use this method to determine the heating regime from which the chars were created. In order to achieve this Project ImpCHAR will experimentally recreate the heating conditions in a - laboratory setting in order to determine the most likely mechanism of charcoal formation. This will allow developing a method of unequivocally identifying small impact craters developed in vegetated unconsolidated sediments: up to this point most of - those kinds of structures could be identified only based on circumstantial evidence of co-existing crater-like shape and occurrence of meteorites. Additionally, ImpCHAR will critically disentangle debate surrounding the energy release during - formation of small impact craters. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ImpChar - - - H2020-MSCA-IF-2016 - - - 749157 - - - - - THE UNIVERSITY OF EXETER - - - EUR 183 454,80 - - - Selection for antimicrobial resistance in a complex community context - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Increased antibiotic resistance (AMR) in a wide range of human pathogens is a growing public health threat, and the World Health Organization (WHO) forecasts a post-antibiotic era for the 21st century (WHO, 2014). The - evolution of AMR in bacteria is determined by both the acquisition of resistance through horizontal gene transfer or chromosomal mutation and by the way resistance affects the competitive ability of a microbe in the presence and absence of - antibiotics. - - - 2019-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SARCOM - - - H2020-MSCA-IF-2016 - - - 751699 - - - - - AALTO-KORKEAKOULUSAATIO - - - EUR 249 793,20 - - - Micromechanics-based finite element modeling of sandwich structures - - - EUR 249 793,20 - - - Finland - - - Higher or Secondary Education Establishments - - The use of novel steel sandwich panels in ship decks instead of conventional stiffened plates offers more economical and energy-efficient designs through material, space and fuel savings. To analyse the global structural - response of a large ship within computational limits, the sandwich panels need to be modeled in an averaged (homogenized) sense without accounting for every small detail. Motivated by this, my objective is to develop simplified theoretical and - computational micromechanics-based beam and plate models for sandwich panels that have unidirectional structural cores and flexible joints. The key theoretical modeling idea is to consider periodic panels as discrete lattices which are replaced by - energetically equivalent, linear micropolar continuum beam and plate models. Subsequently, finite element models for the substitute-continuum beams and plates are formulated. Contrary to existing methods, the proposed approach includes all the - necessary features. First, it fully accounts for flexible (e.g. laser-welded) joints of the panels. Second, the determination of all model parameters is straightforward. Third, the derived models can be easily implemented later in various readily - available finite element software. - - - 2020-08-22, ongoing project - - - 2017-08-23 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Finland - - - SANDFECH - - - H2020-MSCA-IF-2016 - - - 745770 - - - - - INSTITUTE OF FOOD RESEARCH - - - EUR 183 454,80 - - - Fermentation And behaviour of carbohydrates in the colon - - - EUR 183 454,80 - - - United Kingdom - - - Research Organisations - - Irritable bowel syndrome (IBS) is one of the most commonly diagnosed conditions in the EU with a prevalence of 10-15%, and although not fatal, it is associated with significant co-morbidities and societal costs. The causes of - IBS are not well understood, although it has been suggested that there are dietary triggers of the disease, in particular fermentable carbohydrates such as resistant starch (RS). It is believed that alterations to the gut microbiota in IBS sufferers’ - leads to changes in the mechanism of fermentation of carbohydrates, resulting the symptoms such as abdominal pain, bloating and diarrhoea commonly associated with IBS. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - United Kingdom - - - FABCARB - - - H2020-MSCA-IF-2016 - - - 747438 - - - - - THE UNIVERSITY OF EXETER - - - EUR 195 454,80 - - - Experimental Programme Investigating Cumulative Culture - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Humans exhibit a rich and complex material culture with no equivalent in other animals. The unique human capability to accumulate cultural innovations across time allows us to develop powerful technology and drives - technological progress. Despite a growing literature investigating cumulative culture, the underlying processes at play in the accumulation of cultural knowledge remain puzzling. The overarching aims of this proposal are to identify the requirements - of human cumulative culture both at the individual and population levels and improve our understanding of factors that affect the pace of cultural accumulation. During the course of this action, we will develop innovative experimental methods to - investigate three important and timely lines of research and shed new light on the complex processes that underlie cultural accumulation: 1) Identify the cognitive requirements of innovation production and transmission, 2) Evaluate the interplay - between population structure and cultural accumulation, 3) Evaluate the effects of ecological factors on the rate of innovation. This action will use lab experiments from psychology and economics and will bring knowledge from anthropology and biology - to help explain why only humans are able to accumulate cultural information across time and why rates of cultural accumulation have varied in our evolutionary past. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - EPICC - - - H2020-MSCA-IF-2016 - - - 748310 - - - - - KAROLINSKA INSTITUTET - KAROLINSKA INSTITUTET - KAROLINSKA INSTITUTET INNOVATIONS AB - - - EUR 150 000 - - - Novel viral therapy through targeting DNA repair - - - EUR 150 000 - - - Sweden - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Natural epidemics and outbreaks of emerging infectious diseases are a growing problem internationally. RNA viruses remain under constant attention due to the recent Zika virus (ZIKV) outbreak with potential causal relationship - with microcephaly of newly born babies and Ebola virus (EBOV) and Crimean-Congo hemorrhagic fever virus (CCHFV) causing life threatening hemorrhagic fever, demonstrating how zoonotic viruses pose a major global health concern. There is an ongoing - need to discover novel therapies to battle these pathogenic viruses given that no specific therapy exists. Developing new antiviral treatments by targeting host cell proteins needed in the viral life cycle is an emerging strategy to improve - therapeutic power and reduce acquired drug resistance. - - - 2018-12-31, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Sweden - - - NOVITREP - - - ERC-2016-PoC - - - 755150 - - - - - THE UNIVERSITY OF EXETER - - - EUR 263 943 - - - Individual Specialisation in Established Biological Invasions: importance and Ecological Impact - - - EUR 263 943 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Differences between individuals are the substance on which natural selection acts; and individual variation has been identified in many ecological dimensions including diet, habitat use and other behavioural traits. It is - therefore surprising that this variation is rarely considered within an invasion biology framework, particularly given the enormous biological and economic costs imposed by established invasive species – those introduced by humans that aggressively - expand outside their native range. Little is known about how individual traits influence established invasions, to the extent that it has been argued that either bold, highly competitive individuals, or individuals that are cautious and less - aggressive, may be successful. The impacts of different individual invader phenotypes as risks for native biota are also largely unknown, yet this knowledge is key for effective management. This project will, for the first time, determine: i) the - extent, covariance and persistence of variation in multiple traits (dietary, behavioural and cognitive) in individual invasive rats simultaneously and in the wild; ii) the impact of the fundamental ecological processes of competition and predation on - effective trait combinations i.e. individual phenotypes; iii) the consequences of different phenotypes for native biota. With invasion rates continuing to increase globally, this multidisciplinary approach draws upon cutting-edge techniques from - behavioural ecology, comparative psychology, conservation and invasion biology. It provides novel empirical tests of theory, examining hypotheses untested in individual invaders or individuals of any species in natural contexts. The results will have - important implications for theoretical understanding of natural selection, and will integrate individual and community processes in the study of invasive species. They will also be of major importance for applied conservation management actions - addressing a key EU and global problem. - - 2020-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - ISEBI - - - H2020-MSCA-IF-2016 - - - 747120 - - - - - BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION - BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION - - - EUR 149 375 - - - High Performance Genomics for Software Defined Infrastructures - - - EUR 149 375 - - - Spain - Spain - - - Research Organisations - Research Organisations - - The Hi-OMICS PoC aims to pave the road to commercialisation of the Hi-OMICS Controller, a Software Defined Infrastructure Controller (SDI) specifically designed to efficiently manage Computational Genomics workloads running on upcoming SDI platforms. - - - 2019-03-31, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Spain - - - Hi-OMICS - - - ERC-2017-PoC - - - 768626 - - - - - ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON - IQUADRAT INFORMATICA SL - ERICSSON AB - NESSOS AE OLOKLIROMENON LISEON KAI SISTIMATON PLIROFORIKIS - NEC EUROPE LTD - EURECOM - UNIVERSITY OF YORK - MTN CYPRUS LIMITED - FUNDACIO PER A LA UNIVERSITAT OBERTA DE CATALUNYA - POLITECNICO DI MILANO - - - EUR 3 813 484,32 - - - Single Point Of aTtachment communications empowered by cLoud computing and bIG data analytics running on-top of massively distributed and loosely-coupled Heterogeneous mobile data neTworks - - - EUR 3 813 484,32 - - - Greece - Spain - Sweden - Greece - United Kingdom - France - United Kingdom - Cyprus - Spain - Italy - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - To handle the unprecedented demand for mobile data traffic, different vendors, operators and research programmes have aimed to develop radio access technologies (RATs) that boost physical-layer link capacity, utilize - millimeter wave radio, or further densify network topology. Notable steps have also been made towards shifting baseband processing from the (currently) ultra dense network edge to a central location where coordinated resource management will be - performed. Nonetheless, the today’s mobile network ecosystem includes vastly heterogeneous, evidently overlapping (in coverage) and fully isolated (in operation) attachment points that still handle most of the functions necessary for mobile data - communications independently. Aiming to meet and surpass the requirements set for the 5G-and-Beyond mobile data network, in SPOTLIGHT we will create a fully-integrated and multi-disciplinary network of Early Stage Researchers (ESRs) that will - analyze, design, and optimize the performance of a disruptive new mobile network architecture: the SPOTLIGHT architecture. This architecture promises to break performance limitations present to the currently loosely inter-connected, - resource-fragmented and isolated in operation mobile network ecosystem, by transforming the currently loosely-coupled multitude of heterogeneous and multi-layered RATs to a flat coalition of massively distributed antenna sub-systems that are - optimally orchestrated by a cloud-empowered network core. Our primary aim will be to support for the first time self-including yet ultra-reliable radio communications at the edge network. To further reduce response time and enhance network - resilience, all functions necessary for mobile communications will be subject of i) massive parallelization in cloud platforms at the network core and ii) big data analysis running on-top of a virtual pool of shared energy, radio, computing and - storage resources at the network. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Greece - - - SPOTLIGHT - - - H2020-MSCA-ITN-2016 - - - 722788 - - - - - THE UNIVERSITY OF EXETER - THE UNIVERSITY OF EXETER - - - EUR 1 998 722 - - - Context, Identity and Choice: Understanding the constraints on women's career decisions - - - EUR 1 998 722 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - There has been vast improvement in workplace gender equality, but there remain marked differences in the roles in which women and men work. Explanations for this inequality have focused on the barriers women face. However, as - women begin to enter male-dominated roles, a new explanation has arisen: that remaining gender inequality must reflect fundamental differences between women and men, including differences in (a) ambition and desire for power, (b) needs for work-life - balance, and (c) willingness to take career risks. Central to this analysis is the assumption that the glass ceiling is broken and thus inequality must be due to women’s active choices. This explanation downplays the fact that social context - continues to be a barrier to women’s success and places responsibility for gender inequality on women themselves. Indeed, there has arisen the suggestion that gender equality necessitates women overcoming ‘internal obstacles’, ‘leaning-in’ and - altering their choices (Sandberg, 2013), rather than challenging the status quo. I argue that diametrically contrasting structural barriers with women’s choices is unhelpful. Instead, I suggest that women’s choices are shaped and constrained by the - gendered nature of organisational and social contexts and how women see themselves within these contexts. I propose a programme of research, across 3 integrated streams, that investigates how social and organisational structures define identities and - constrain women’s choices in relation to ambition, work-life balance, and career risk-taking. I have four key objectives: (1) to clarify how organisational and social contexts define identity and constrain women’s choices, (2) to use an - interdisciplinary, multi-methodological approach, to produce innovative theory and data, (3) to work collaboratively with stakeholders, and (4) to inform practical interventions designed to facilitate the increase of women’s participation in hitherto - male-dominated roles. - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - CIC - - - ERC-2016-COG - - - 725128 - - - - - DUBLIN INSTITUTE FOR ADVANCED STUDIES - DUBLIN INSTITUTE FOR ADVANCED STUDIES - - - EUR 1 853 090 - - - Ejection Accretion Structures in YSOs (EASY) - - - EUR 1 853 090 - - - Ireland - Ireland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - For a number of reasons, in particular their proximity and the abundant range of diagnostics to determine their characteristics, outflows from young stellar objects (YSOs) offer us the best opportunity of discovering how - astrophysical jets are generated and the nature of the link between outflows and their accretion disks. Models predict that the jet is initially launched from within 0.1 to a few au of the star and focused on scales at most ten times larger. Thus, - even for the nearest star formation region, we need high spatial resolution to image the “central engine” and test current models. - - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Ireland - - - EASY - - - ERC-2016-ADG - - - 743029 - - - - - UNIVERSITA DELLA SVIZZERA ITALIANA - UNIVERSITA DELLA SVIZZERA ITALIANA - - - EUR 2 500 000 - - - Recurrent Neural Networks and Related Machines That Learn Algorithms - - - EUR 2 500 000 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Recurrent neural networks (RNNs) are general parallel-sequential computers. Some learn their programs or weights. Our supervised Long Short-Term Memory (LSTM) RNNs were the first to win pattern recognition contests, and - recently enabled best known results in speech and handwriting recognition, machine translation, etc. They are now available to billions of users through the world's most valuable public companies including Google and Apple. Nevertheless, in lots of - real-world tasks RNNs do not yet live up to their full potential. Although universal in theory, in practice they fail to learn important types of algorithms. This ERC project will go far beyond today's best RNNs through novel RNN-like systems that - address some of the biggest open RNN problems and hottest RNN research topics: (1) How can RNNs learn to control (through internal spotlights of attention) separate large short-memory structures such as sub-networks with fast weights, to improve - performance on many natural short-term memory-intensive tasks which are currently hard to learn by RNNs, such as answering detailed questions on recently observed videos? (2) How can such RNN-like systems metalearn entire learning algorithms that - outperform the original learning algorithms? (3) How to achieve efficient transfer learning from one RNN-learned set of problem-solving programs to new RNN programs solving new tasks? In other words, how can one RNN-like system actively learn to - exploit algorithmic information contained in the programs running on another? We will test our systems existing benchmarks, and create new, more challenging multi-task benchmarks. This will be supported by a rather cheap, GPU-based mini-brain for - implementing large RNNs. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Switzerland - - - AlgoRNN - - - ERC-2016-ADG - - - 742870 - - - - - THE UNIVERSITY OF EXETER - THE UNIVERSITY OF EXETER - STICHTING VU - - - EUR 1 854 256 - - - Average - Transaction Costs and Risk Management during the First Globalization (Sixteenth-Eighteenth Centuries) - - - EUR 1 854 256 - - - United Kingdom - United Kingdom - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project focuses on the historical analysis of institutions and their impact on economic development through the investigation of a legal instrument – general average (GA) – which underpins maritime trade by redistributing - damages’ costs across all interested parties. This will be pursued through the comparative investigation of GA in those European countries where substantial data exists: Italy, Spain, England, France and the Low Countries (1500-1800). Average and - insurance were both created in the Middle Ages to facilitate trade through the redistribution of risk. Insurance has been widely studied, average – the expenses which can befall ships and cargoes from the time of their loading aboard until their - unloading (due to accidents, jettison, and unexpected costs) – has been neglected. GA still plays an essential role in the redistribution of transaction costs, and being a form of strictly mutual self-protection, never evolved into a speculative - financial instrument as insurance did; it therefore represents an excellent case of long-term effectiveness of a non-market economic phenomenon. Although the principle behind GA was very similar across Europe, in practice there were substantial - differences in declaring and adjudicating claims. GA reports provide unparalleled evidence on maritime trade which, analysed quantitatively and quantitatively through a novel interdisciplinary approach, will contribute to the reassessment of the role - played by the maritime sector in fostering economic growth during the early modern first globalization, when GA was the object of fierce debates on state jurisdiction and standardization of practice. Today they are regulated by the York-Antwerp Rules - (YAR), currently under revision. This timely conjuncture provides plenty of opportunities for active engagement with practitioners, thereby fostering a creative dialogue on GA historical study and its future development to better face the challenges - of mature globalization. - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - AveTransRisk - - - ERC-2016-COG - - - 724544 - - - - - THE UNIVERSITY OF EXETER - THE UNIVERSITY OF EXETER - - - EUR 1 499 462 - - - The cultural evolution and ecology of institutions: An integrated evolutionary approach to the interrelated rules that regulate human social organization and cooperation - - - EUR 1 499 462 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Humans live in groups of huge numbers of genetically unrelated individuals due to culturally-inherited social rules (“institutions”) that structure groups and provide solutions to coordination and collective action problems. - However, only in certain places have societies developed more “inclusive” institutions (e.g. democratic governance, the rule of law) that enable the majority of the population (not just elites) to participate in economic and political activities. - Fundamental questions about the evolution of institutions still remain. This project will go beyond existing research by employing an overarching cultural evolutionary framework to address a number of outstanding issues such as: How do institutions - evolve over time?, How do cultural and ecological factors affect how institutions emerge and spread?, Why have certain institutions emerged or been adopted in only a limited number of places? I will apply innovative statistical, computational and - theoretical models from biology to formally and rigorously test a range of hypotheses concerning the evolution of institutions. The project has 3 main objectives (O). In O1 I will use phylogenetic methods to infer the entangled evolutionary history - of the institutions that groups possess. In O2 I will employ epidemiological and comparative statistical models, to investigate what factors affect the probability of institutions spreading between societies. In O3 I will use computer simulations to - examine how ecological and social factors have led to the emergence of institutions for collective action in some parts of the world but not others. The objectives of this project therefore involve both modelling and empirically assessing theories - using cross-national and historical data on institutions and other relevant variables. This more integrated approach will create a step-change in our understanding of institutional change and how evolutionary and ecological processes have shaped the - world we live in today. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - EVORULES - - - ERC-2016-STG - - - 716212 - - - - - THE UNIVERSITY OF EXETER - THE UNIVERSITY OF EXETER - PHILIPPS UNIVERSITAET MARBURG - - - EUR 1 499 623 - - - Forms of Law in the Early Modern Persianate World, 17th-19th centuries - - - EUR 1 499 623 - - - United Kingdom - United Kingdom - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project will study concepts and practices of law across the early modern Persianate world, investigating how this specific cultural milieu structured understanding of law, legal expression and efforts to secure rights and - justice. It will do so by focusing on the ordinary users of law, rather than on specialists, and by using legal documents written in Persian and associated languages produced in five major linguistic-cultural zones stretching from the Indian - subcontinent to Iran and the northern and western Indian Ocean. Working with the surviving record of everyday transactions (legal deeds); formularies that standardised such legal forms; extant adjudication records and relevant jurisprudential - literature, we shall pay particularly close attention to language – exploring how translation, multi-lingualism, orality and literacy facilitated processes of vernacularisation of Islamic law, and was actuated through the social and material world of - writing. - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - Lawforms - - - ERC-2016-STG - - - 714569 - - - - - IIGM FOUNDATION - UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6 - BEATSON INSTITUTE FOR CANCER RESEARCH LBG - - - EUR 900 000 - - - New algorithms for inference and optimization from large-scale biological data - - - EUR 900 000 - - - Italy - France - United Kingdom - - - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - - The tremendous technological advance underlying the ongoing genomic revolution in the life sciences has profoundly transformed biological research over the last 10-15 years. The grand challenge ahead is to leverage - experimental progress like high-throughput sequencing by developing effective tools for large scale data-based inference and optimization. The goals of INFERNET rely on the transfer of ideas and methods developed in recent years at the boundary - between statistical physics and information theory into the world of quantitative biology. We aim at setting up a consortium characterized by a proven track-record of high-quality research in order to implement a highly integrated program leading - from the design of new algorithms to concrete biological applications. The consortium will provide the optimal environment to nurture a generation of researchers that will drive new developments at the forefront of these challenging fields. - - 2021-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Italy - - - INFERNET - - - H2020-MSCA-RISE-2016 - - - 734439 - - - - - KARLSRUHER INSTITUT FUER TECHNOLOGIE - KARLSRUHER INSTITUT FUER TECHNOLOGIE - - - EUR 149 875 - - - Scanner for novel chemical reactions - - - EUR 149 875 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Funded by the ERC-Starting Grant COMBIPATTERNING, we have developed a novel nanolayer-based synthesis based on patterning different materials with laser radiation in form of a pan-cake spots in array format. Our synthesis - robot can do it for many different materials, for >40.000 spots per glass slide, in exactly defined stoichiometries, and for <200 € costs. The robot uses short laser pulses to transfer <1ng “punched-out” material per spot from a donor foil - to a synthesis slide. Then, the reactants embedded in the nano thin polymer pan-cake spots can mix with each other and thus undergo chemical reactions by heating the synthesis slide. Due to the large progress in MALDI imaging and the fluorescent - scanners, the results of the reactions can be analyzed in the same array format. The masses found by MALDI imaging in some spots might help us to identify unknown chemical reactions. We believe that the nanolayer-based synthesis developed by us might - be a basis for future chemistry stations linking scientists and accelerating their studies to screen for novel chemical reactions in a high throughput manner. Instead of studying the interaction between reactants in a single test glass, the chemists - will just spin-coat their educts on microscope slides and supply them together with a file for desired reactant combinations to the server - chemical reaction scanner. Therefore, we want to verify the innovation potential of the nanolayer-based - synthesis that should find a market where a novel synthesis strategy on combining novel building blocks should be developed, especially, in the field of novel bioactive chemicals and fluorophores. - - 2019-04-30, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Germany - - - CHEMREACTIONSCAN - - - ERC-2017-PoC - - - 766695 - - - - - HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF EV - ANKARA UNIVERSITESI - AARHUS UNIVERSITET - CONSORCIO PARA LA CONSTRUCCION EQUIPAMIENTO Y EXPLOTACION DEL LABORATORIO DE LUZ SINCROTRON - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - STIFTUNG DEUTSCHES ELEKTRONEN-SYNCHROTRON DESY - DIAMOND LIGHT SOURCE LIMITED - ELETTRA - SINCROTRONE TRIESTE SCPA - EUROPEAN X-RAY FREE-ELECTRON LASERFACILITY GMBH - HELMHOLTZ-ZENTRUM BERLIN FUR MATERIALIEN UND ENERGIE GMBH - ISTITUTO NAZIONALE DI FISICA NUCLEARE - INSTALLATION EUROPEENNE DE RAYONNEMENT SYNCHROTRON - KARLSRUHER INSTITUT FUER TECHNOLOGIE - LUNDS UNIVERSITET - PAUL SCHERRER INSTITUT - STICHTING KATHOLIEKE UNIVERSITEIT - SYNCHROTRON-LIGHT FOR EXPERIMENTAL SCIENCE AND APPLICATIONS IN THE MIDDLE EAST - Société civile SYNCHROTRON SOLEIL - UNIWERSYTET JAGIELLONSKI - - - EUR 9 997 538,88 - - - Convenient Access to Light Sources Open to Innovation, Science and to the World - - - EUR 9 997 538,88 - - - Germany - Turkey - Denmark - Spain - France - Germany - United Kingdom - Italy - Germany - Germany - Italy - France - Germany - Sweden - Switzerland - Netherlands - Jordan - France - Poland - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - - In the present project, CALIPSOplus, the relevant synchrotrons and free electron lasers in Europe and the Middle East join forces to contribute to the completion of ERA and to tackle the new challenges arising from the - commitment of the EU to Open science, Open innovation and Open to the world. Integration with respect to user access, support, instrumentation, data analysis and data management is strongly pushed forward by this advanced community, looking back at a - long tradition of integrated activities funded under FP6 and FP7, and largely profiting from the experiences already gained. The European Synchrotron and FEL User Organisation will be consolidated and the performance and use of the wayforlight portal - as pivotal platform of the light sources community will be boosted. Data management of the different facilities will be harmonised and a data management plan for the CALIPSOplus consortium be defined. Particular focus will be on leveraging scientific - excellence in EU-13 countries and on widening the use of light sources by users from these regions. This will be achieved by visits to universities in these countries, by dedicated schools and by an especially set-up Twinning programme. As a pilot - action a specific Trans-national Access programme will be offered for users from SMEs, closely related to an awareness raising campaign for light sources use and the role of light sources as customers among local industry around the facilities. - - - 2021-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.2."> - - - INFRAIA-01-2016-2017 - Integrating Activities for Advanced Communities - - - RIA - Research and Innovation action - - - Germany - - - CALIPSOplus - - - H2020-INFRAIA-2016-1 - - - 730872 - - - - - Institute of Mechanics, Bulgarian Academy of Sciences - CONSIGLIO NAZIONALE DELLE RICERCHE - NARRANDO SRL - UNIVERSITE DE NAMUR ASBL - UNIVERSITA DEGLI STUDI DI SALERNO - RESEARCH AND DEVELOPMENT OF NANOMATERIALS AND NANOTECHNOLOGY NANO TECHLAB LTD - ILIA VEKUA SOKHUMI INSTITUTE OF PHYSICS AND TECHNOLOGY - - - EUR 1 651 500 - - - Multifunctional Graphene-based Nanocomposites with Robust Electromagnetic and Thermal Properties for 3D-printing Application - - - EUR 1 935 000 - - - Bulgaria - Italy - Italy - Belgium - Italy - Bulgaria - Georgia - - - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - - Graphene 3D project proposes highly innovative pathway for the development of optimized, multifunctional graphene-based polymer composites and structures with desired properties for specific applications, based on combination - of three main approaches: (i) controlled processing and material’s characterization; (ii) robust nanocomposite design; and (iii) modeling/optimization of nanocomposite cellular structures with predefined properties. Graphene 3D methodology will - result in two major outcomes: Multifunctional nanocomposite material for 3D printing application, as well as Optimized and experimentally validated, 3D printed nanocomposite cellular structures with tunable electromagnetic, thermal and mechanical - properties. To reach the goal, the proposal will pursue the following main objectives: (1) to develop an effective processing technique for graphene-based polymer nanocomposite; (2) to correlate processing variables with final micro and nanostructure - features; (3) to obtain highly improved nanocomposite properties (electrical, electromagnetic, mechanical, thermal); (4) to propose robust design tool for optimizing process-structure-property-performance parameters, resulting in optimized - nanocomposite formulation for 3D printing application; (5) to design nanocomposite-based cellular structures with optimum configuration (structure, geometry) and tunable multifunctional characteristics in view of predefined performances; (6) to prove - the design concept by fabrication and experimental validation of both nanocomposite material and 3D printed cellular structures that achieve unique properties. Project research & innovation ideas will bring up the research results from TRL 1-2 to - TRL 3-4, with potential for application specified towards high power electronics. Graphene 3D will create a Joint Laboratory on graphene-polymer research for knowledge share in a multidisciplinary international/inter-sectoral consortium having - long-term implication. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Bulgaria - - - Graphene 3D - - - H2020-MSCA-RISE-2016 - - - 734164 - - - - - UNIVERSITAT KONSTANZ - UNIVERSITAT KONSTANZ - - - EUR 147 000 - - - Blended Learning Course for Police Students: Death Notification with Responsibility - - - EUR 147 000 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The aim of the proposed transfer project is to develop the blended learning course „Death Notification with Responsibility“ (DNR) for police officers. In situations of unnatural death (accidents, suicides, terror attacks or - other forms of violence), police officers have to deliver a death notification to the family members of the deceased. Unnatural death is the worst possible message to be delivered. It will change the lives of those informed decisively and will remain - in their memories forever. The core findings of the ERC project „Narratives of Terror and Disappearance“ (NoT-240984) established the devastating social effects of uncertainty caused by non-information and the material absence of bodies in - confrontation with violent death. - - - 2018-11-30, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Germany - - - DNR - - - ERC-2016-PoC - - - 754949 - - - - - UNIVERSITY OF LEEDS - UNIVERSITY OF LEEDS - - - EUR 150 000 - - - Low Cost Material for Exhaust Catalysis (LowCat) - - - EUR 150 000 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project aims to develop a low cost catalyst to replace the Platinum Group Metals (PGMs) that are widely used in automotive exhaust catalysis. The ERC Advanced Grant project CODITA (project number 291332) is an - investigation into the impacts of cosmic dust in planetary atmospheres. During the course of the project we have developed a novel laboratory synthesis of cosmic dust particle analogues. The kinetics of CO oxidation on this material were studied in - order to model the heterogeneous oxidation of CO to CO2 in the troposphere of Venus, where the temperature ranges from 120 - 440°C. Noting that the conditions on Venus are strikingly similar to those in a vehicle exhaust, this discovery forms the - basis of the LowCat proposal. Preliminary experiments show that NO is readily taken up on LowCat, which is the first step in the NOx reduction process. The implication is that LowCat could be developed into a 3-way catalyst that is significantly less - expensive than current PGM catalysts. This discovery presents an exciting commercialisation opportunity, with very significant societal impacts. Moving toward market requires a proof of core science, patenting of the discovery and commercialisation. - The 18 month project planned has specified milestones, project deliverables and value proposition. There are four objectives in the proposal: 1) determine the potential of LowCat to catalyse the reduction of NO in the presence of ammonia; 2) engineer - the catalyst onto a suitable support monolith; 3) carry out diesel engine exhaust trials; 4) commercialise the discovery through a patent application and engagement with an industrial partner and potential license. - - 2018-12-31, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - LOWCAT - - - ERC-2017-PoC - - - 768101 - - - - - UNIVERSITAT AUTONOMA DE BARCELONA - UNIVERSITAT AUTONOMA DE BARCELONA - - - EUR 150 000 - - - Application of genomic inversions as diagnostic markers in precision medicine - - - EUR 150 000 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Despite the initial high expectations of genome variation studies, only a small proportion of the genetic risk of common and complex diseases has been identified so far. Most of the work has focused on single nucleotide - polymorphisms (SNPs) and copy number variants (CNVs). Inversions, on the other hand, are a type of structural variant that affects a large fraction of the human genome and is implicated in phenotypic differences in diverse organisms. However, they - have been poorly studied because their specific characteristics make their detection especially challenging and how much they contribute to human diseases is not yet well known. As part of the INVFEST ERC Starting Grant, we have developed a novel - high-throughput technique for genotyping multiple human inversions in hundreds of individuals, which opens new opportunities in the characterization of inversion functional effects and their association with diseases. The aim of the IN2DIAG project - is to increase the value of this technology as an innovative diagnostic kit for human inversions that could be licensed to an industrial partner for its commercialization. To achieve that, the main goals are: (1) Carry out a proof of principle study - of the association of inversions and 10 common diseases and other health-relevant traits to demonstrate the potential applicability of the technology; (2) Extend the current market research of inversion genotyping needs in a clinical setting and - strengthen the contacts with potential licensees and end-user companies; and (3) Maintain the current IPR strategy and if necessary expand this protection with additional patents of possible new discoveries. Our project therefore involves a combined - approach, strengthening both the scientific and commercial aspects of the technology, to bring to the market a new tool for the analysis of previously unknown genetic variants, helping to fulfill precision medicine promises. - - 2018-12-31, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Spain - - - IN2DIAG - - - ERC-2016-PoC - - - 755027 - - - - - UNIVERSITAET INNSBRUCK - UNIVERSITAET INNSBRUCK - LUDWIG BOLTZMANN GESELLSCHAFT GMBH - - - EUR 2 421 223,75 - - - Nova Scientia. Early Modern Scientific Literature and Latin - - - EUR 2 421 223,75 - - - Austria - Austria - Austria - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - Fundamental changes occurred in the study of nature between the late 15th and 18th centuries, leading to the emergence of modern science as we know it. This process would have been impossible without Latin as the scientific - lingua franca of the era, just as today's science is hard to imagine without English. At present, this crucial role of Latin is insufficiently acknowledged, and the hundreds of thousands of scientific texts written in Latin have largely remained - neglected. This severely limits the scope of research into the history of early modern science, an otherwise thriving field. - - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Austria - - - NOSCEMUS - - - ERC-2016-ADG - - - 741374 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 149 293 - - - A Photothermal Lateral Flow Test for Visual Point of Care Detection - - - EUR 149 293 - - - Spain - Spain - - - Research Organisations - Research Organisations - - The rapid development of cost-effective and efficient biosensors has had a profound worldwide socioeconomic impact. Advances in the fields of microelectronics, materials science and nanotechnology have been vital to the - implementation of enhanced sensing platforms aimed at providing alternatives to traditional analytical methods. Further, current sensing platforms are often slow, unreliable and expensive; in particular, when ultralow concentration detection is - required. Although progress in the biosensors field typically focuses on clinical point-of-care diagnosis, a clear demand exists in areas such as food safety regulation, environmental policy, military and the arts, where time, cost, portability and - ease-of-use of the device are critical. The grand aim of HOTFLOW is to develop an innovative, rapid, inexpensive, versatile and sensitive thermal transduction biosensor for the ultralow detection and quantification of relevant proteins such as - tumoral markers. This novel sensing technology will use detection biomolecules linked to plasmonic gold nanoprisms which serve as thermal transducers by based on a lateral flow immunoassay and a “sandwich” recognition strategy with capture - biomolecules immobilized on a dual-active nitrocellulose membrane support/thermosensitive paper that subsequently functions as photographic and tracing detection element. Although the ambitious thermal sensing device proposed here will be prototyped - using simple analytes, this ERC POC project goes significantly beyond the current state-of-the-art in nanoplasmonics and biosensing by proposing the development and elaboration of an almost universal paper-based thermal sensing device. This - technology will be implemented and validated by applying it to a specific problem, gastrointestinal cancer diagnosis. - - 2019-01-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Spain - - - HOTFLOW - - - ERC-2016-PoC - - - 754609 - - - - - Institute of Science and Technology Austria - Institute of Science and Technology Austria - - - EUR 2 306 862 - - - Interaction and feedback between cell mechanics and fate specification in vertebrate gastrulation - - - EUR 2 306 862 - - - Austria - Austria - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Embryogenesis is achieved by the close interplay between the gene regulatory networks that control cell fate specification and the physical processes by which the embryo takes shape. While each of these systems has been - extensively investigated over the past decades, comparably little is yet known about how they functionally interact across different scales of organization within the physiological context of the developing embryo. The central aim of this proposal is - to elucidate the fundamental principles underlying the interaction and feedback between cell mechanics and fate specification during vertebrate gastrulation. Using zebrafish as a vertebrate model organism, we will explore how germ layer progenitor - cell fate specification affects the physical processes by which the gastrula takes shape, and, vice versa, how alterations in cell/tissue mechanics feed back onto the gene regulatory networks and signals controlling progenitor cell fate specification - during gastrulation. To dissect the fundamental mechanisms underlying this crosstalk, we will combine genetic, cell biological and biophysical experimentation with mathematical modeling. We expect that this transdisciplinary approach will provide - answers to a central yet unresolved question in developmental biology: how the interplay between cell mechanics, dynamics and fate specification drives embryo morphogenesis and patterning. - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Austria - - - MECSPEC - - - ERC-2016-ADG - - - 742573 - - - - - STOCKHOLMS UNIVERSITET - STOCKHOLMS UNIVERSITET - - - EUR 2 324 391 - - - Axions: From Heaven to Earth - - - EUR 2 324 391 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Axions are hypothetical particles whose existence would solve two major problems: the strong P, T problem (a major blemish on the standard model); and the dark matter problem. It is a most important goal to either observe or - rule out the existence of a cosmic axion background. It appears that decisive observations may be possible, but only after orchestrating insight from specialities ranging from quantum field theory and astrophysical modeling to ultra-low noise quantum - measurement theory. Detailed predictions for the magnitude and structure of the cosmic axion background depend on cosmological and astrophysical modeling, which can be constrained by theoretical insight and numerical simulation. In parallel, we must - optimize strategies for extracting accessible signals from that very weakly interacting source. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Sweden - - - AXION - - - ERC-2016-ADG - - - 742104 - - - - - THE UNIVERSITY OF LIVERPOOL - THE UNIVERSITY OF LIVERPOOL - - - EUR 149 893 - - - New thermo-regulating paints based on nanoencapsulation of phase-change materials - - - EUR 149 893 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - "The proposal is focused on the innovation potential of thermo-regulating paints for effective thermal insulation and controlled release/uptake of the thermal energy in buildings. These thermo-regulating paints are based on - the energy nanocapsules with encapsulated phase change materials, which are under development in ERC 2014 Consolidator grant No. 647969 "ENERCAPSULE", and current commercial paint formulations. The addition of the energy nanocapsules able to store - and release heat will provide commercial paints thermo-regulating properties. The advantage of energy nanocapsules in the paint formulations is the isolation of the phase-change heat capacitors from the other components of the paint. This will keep - the integrity of the encapsulated phase-change materials during heating/cooling cycles, prevent the interaction between paint matrix and phase-change material and, as a result, significantly increase the durability of the thermo-responsive paints to - thousands of heating/cooling cycles. - - 2019-04-30, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - ENERPAINT - - - ERC-2017-PoC - - - 767173 - - - - - DEUTSCHES KREBSFORSCHUNGSZENTRUM - DEUTSCHES KREBSFORSCHUNGSZENTRUM - - - EUR 2 006 250 - - - Detecting, understanding and exploiting intracellular redox signaling relays - - - EUR 2 006 250 - - - Germany - Germany - - - Research Organisations - Research Organisations - - Redox signaling is a process by which endogenous oxidants, derived from metabolism, reversibly modify particular thiols on particular proteins to change their functional behavior in an adaptive manner. However, the molecular - mechanisms of redox signaling remain largely unknown. In particular, specificity and efficiency of redox signaling remain unexplained. The now emerging solution to this conundrum is that redox signaling is mediated and channeled by protein-to-protein - redox relay chains that dynamically assemble in the cytosolic, nuclear and mitochondrial compartments. We and others have found that H2O2 signals are relayed through thiol peroxidases to neighboring proteins within supramolecular assemblies. Evidence - now suggests that so far we have just glimpsed the ‘tip of the iceberg’, namely that redox relay chains are ubiquitous and also operate for reactive nitrogen and sulfur species. This project aims to systematically uncover, dissect, monitor and - manipulate the redox relay chains that give specificity and efficiency to redox signaling. The basic strategy is to tag all protein-coding genes with genetically encoded reporters which –within the context of the living cell– sense the transmission - of thiol oxidizing equivalents within their sphere of immediate proximity (≈10 nm). A combination of genetic screening, redox proteomics and transcription profiling will then allow to identify the composition of redox relays, their endogenous target - proteins und their functional impact on gene regulation. The knowledge about the composition of redox relays will lead to precision tools for the observation and manipulation of defined redox signaling pathways in vivo. The project is expected to - yield fundamental insights into the specific molecular links by which reactive oxygen, nitrogen and sulfur species couple changes in metabolism to cellular and organismal adaptations regulating resilience and healthspan. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - Redox Relays - - - ERC-2016-ADG - - - 742039 - - - - - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - - - EUR 149 875 - - - Accurate cell signatures for the advancement of personalized medicine - - - EUR 149 875 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Patient/individual specific cells, including induced pluripotent stem (iPS) cells will be crucial in defining tomorrow’s medicine owing to their uses in drug discovery, immunotherapy or cell therapy. These clinical - applications require the utmost accurate and reliable identity and purity testing, however, the majority of cells stored worldwide fall short of a sufficient level of characterisation. This project aims at validatating and commercializing an - innovative method of diagnostic and quality control for human cells. It is based on our unprecedented ability to measure the expression of millions of uncharted RNA biomarkers called TEs, genetic units that contribute over 50% of the genome but that - have been completely disregarded until very recently, mainly due to the challenge imposed by their complex analysis. Our new methodology provides a high-density barcode of cellular identity, opening the door for individual-specific cells to broad - applications in biotechnology and medicine alike. - - 2018-12-31, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Switzerland - - - Cellphmed - - - ERC-2016-PoC - - - 737562 - - - - - Academisch Medisch Centrum bij de Universiteit van Amsterdam - Academisch Medisch Centrum bij de Universiteit van Amsterdam - - - EUR 150 000 - - - Circulating tumor cells for tailoring BMP targeted therapies - - - EUR 150 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Gastro-intestinal (GI) cancers, including gastro-esophageal junctional (GEJC), gastric (GC), colorectal (CRC) and pancreatic cancer (PC) are devastating malignancies that annually affect over 2 million persons worldwide and - lead to more than 600,000 deaths (Globocan 2012). Given the current trends, the incidence of GI cancer is expected to increase further. Conventional therapies include chemo- and radiation therapy combined with surgery. However, amongst cancer - patients, GI cancer patients have one of the poorest outcomes with a 5-year survival ranging from only 60% for CRC to a mere 5% for PC - - 2018-12-31, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Netherlands - - - CTC4BMP - - - ERC-2016-PoC - - - 737612 - - - - - ACADEMISCH ZIEKENHUIS LEIDEN - ACADEMISCH ZIEKENHUIS LEIDEN - - - EUR 1 999 802,50 - - - The role of complement in the induction of autoimmunity against post-translationally modified proteins - - - EUR 1 999 802,50 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In many prevalent autoimmune diseases such as rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) autoantibodies are used as diagnostic and prognostic tools. Several of these autoantibodies target proteins that - have been post-translationally modified (PTM). Examples of such modifications are citrullination and carbamylation. The success of B cell-targeted therapies in many auto-antibody positive diseases suggests that B cell mediated auto-immunity is - playing a direct pathogenic role. Despite the wealth of information on the clinical associations of these anti-PTM protein antibodies as biomarkers we have currently no insight into why these antibodies are formed. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - AUTOCOMPLEMENT - - - ERC-2016-COG - - - 724517 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 860 962,50 - - - Fast determination of fatigue properties of materials beyond one billion cycles - - - EUR 1 860 962,50 - - - France - France - - - Research Organisations - Research Organisations - - Many mechanical structures are submitted to repeated loadings and can break under stress lower than the ultimate tensile stress. This phenomenon is called the fatigue of materials and can be found in many industrial sectors, - such as the transport industry, aeronautic industry and energy production. Fatigue design is thus crucial in engineering and it requires the precise characterization of material behavior under cyclic loadings to ensure the safety and reliability of - structures throughout their life. An increase in the life span of a structure or a reduction in the number of maintenance phases leads to an increases in the number of cycles applied to this structure. It is presently common to find mechanical - systems subjected to several billion cycles, in what is called the gigacycle fatigue domain. The characterization of the fatigue behavior of materials requires fatigue tests to be conducted until fracture for different stress amplitudes. One problem - with this method is the test duration, which becomes excessive and beyond possible, particularly for a very high number of cycles. The goal of FastMat is to develop a new method that reduces considerably the duration of fatigue characterization. This - method involves the use of only short interrupted tests coupled with a self-heating measurement to characterize the fatigue behavior for very low stress amplitudes. The scientific objective is to develop simultaneously experimental and numerical - tools for the fast determination of fatigue behavior. The experimental approach will be developed to estimate simultaneously the dissipation and the stored energy, which directly reflect fatigue damage. For the numerical approach, discrete - dislocation dynamics simulations will be developed to establish links between the fatigue damage associated with the evolution of dislocation structures, the stored energy and the dissipated energy. - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - France - - - FastMat - - - ERC-2016-COG - - - 725142 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 499 192 - - - Gestures in nonhuman and human primates, a landmark of language in the brain? Searching for the origins of brain specialization for language - - - EUR 1 499 192 - - - France - France - - - Research Organisations - Research Organisations - - Most of language functions are under the left brain control in both left- and right-handers and involve structural asymmetries between the two hemispheres. While this asymmetry was considered as associated with handedness, - such a relation has been recently questioned. Considering the strong language/gesture links in humans and the continuities between the gestural system in apes and monkeys and some language properties, we recently suggested the hypothesis of a - continuity between language lateralization and asymmetry of communicative gestures in both human and nonhuman primates. Given the phylogenetical proximity between those species, comparative research on brain specialization between a non-linguistic - gestural system (i.e., in monkeys) versus a linguistic gestural systems in humans (i.e., sign language in deaf) might help evaluating the gestural continuities with language lateralization in term of manual asymmetries, structural and functional - lateralization of the brain. - - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - GESTIMAGE - - - ERC-2016-STG - - - 716931 - - - - - THE UNIVERSITY OF EXETER - THE UNIVERSITY OF EXETER - - - EUR 2 447 699 - - - Photonically fused molecular materials - - - EUR 2 447 699 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Molecular materials are ubiquitous, encompassing smart phone displays, plastic electronics and the molecular machinery of photosynthesis. Many of these remarkable uses depend on interactions between the molecules. Until now - these interactions have been electric in character, and have been dictated by how electric charge is distributed over the molecules. PHOTMAT will transform the world of molecular materials by adding a new ingredient – photons. I will fuse photons and - molecules together to create new hybrid states – part molecule and part photon – that are dramatically different from those of the constituent molecules and photons. The idea of coupling molecules with photons is a radical new approach with - implications that reach across physics, quantum information, chemistry, materials science, nanotechnology and biology. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - PHOTMAT - - - ERC-2016-ADG - - - 742222 - - - - - UNIVERSITY COLLEGE LONDON - UNIVERSITY COLLEGE LONDON - - - EUR 1 498 069 - - - Analysing South-South Humanitarian Responses to Displacement from Syria: Views from Lebanon, Jordan and Turkey - - - EUR 1 498 069 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Since 2012, over 4 million people have fled Syria in ‘the most dramatic humanitarian crisis that we have ever faced’ (UNHCR). By November 2015 there were 1,078,338 refugees from Syria in Lebanon, 630,776 in Jordan and - 2,181,293 in Turkey. Humanitarian agencies and donor states from both the global North and the global South have funded and implemented aid programmes, and yet commentators have argued that civil society groups from the global South are the most - significant actors supporting refugees in Lebanon, Jordan and Turkey. Whilst they are highly significant responses, however, major gaps in knowledge remain regarding the motivations, nature and implications of Southern-led responses to - conflict-induced displacement. This project draws on multi-sited ethnographic and participatory research with refugees from Syria and their aid providers in Lebanon, Jordan and Turkey to critically examine why, how and with what effect actors from - the South have responded to the displacement of refugees from Syria. The main research aims are: - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - ASSHURED - - - ERC-2016-STG - - - 715582 - - - - - EUROPEAN FUTURE INNOVATION SYSTEM CENTRE - JNP STRATIGIKI KAI EPICHIRISIAKI SYMVOULEFTIKI IKE - ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON - GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER - GEANT LIMITED - PARTNERSHIP FOR ADVANCED COMPUTINGIN EUROPE AISBL - STICHTING EGI - THE UNIVERSITY OF EDINBURGH - CONSIGLIO NAZIONALE DELLE RICERCHE - - - EUR 1 499 037,50 - - - European E-Infrastructure Services Gateway - - - EUR 1 499 037,50 - - - Belgium - Greece - Greece - Germany - United Kingdom - Belgium - Netherlands - United Kingdom - Italy - - - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - Other - Other - Higher or Secondary Education Establishments - Research Organisations - - EInfraCentral's mission is to ensure that by 2020 a broader/ more varied set of users (including industry) benefits from European infrastructures. A common approach to defining and monitoring e-infrastructures services will - increase their uptake. It will also enhance understanding of where improvement can be made in delivering services. The challenge is to shift towards an e-Infrastructure ''market place'' to initiate new service offerings and to engage with a broader - set of users and needs. This will be achieved through an exchange of know-how between e-infrastructures consultations with a broad range of existing or potential users. EInfraCentral will pursue 3 specific objectives: 1. Structure an open and guided - discussion between e-infrastructures to consensually define a common service catalogue 2. Develop a one-stop shop portal for users to browse the service catalogue and enhance the monitoring of key performance indicators that focus on availability and - quality of services and user satisfaction 3. Draw policy lessons for a future European e-infrastructure market place as an extension of the common service catalogue and portal (incorporating a larger number of e-infrastructures). Key highlights of - the proposal are: 1.A multidisciplinary team combining technical knowledge & insights from the e-infrastructure community with independent expertise in community building consultation, policy and data mapping and monitoring 2. A co-design process - that will involve funders, the e-research infrastructure community and a representative user group (incl. SMEs) 3. On-going user interaction will guide the design and development of the eInfraCentral portal (as the main entry point to European - e-infrastructures services) in two phases: a prototype with a first set of services and a full release with a KPI dashboard 4. Reinforce collaboration between e-infrastructures and optimise access to and increase uptake of e-infrastructures services - by end users. - - 2019-06-30, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.3.1., H2020-EU.1.4.1.3., H2020-EU.1.4.3.2."> - - - INFRASUPP-03-2016 - Support to policies and international cooperation for e-infrastructures - - - CSA - Coordination and support action - - - Belgium - - - eInfraCentral - - - H2020-INFRASUPP-2016-1 - - - 731049 - - - - - UNIVERZA V MARIBORU - UNIVERZA NA PRIMORSKEM UNIVERSITA DEL LITORALE - UNIVERZA V NOVI GORICI - NACIONALNI INSTITUT ZA BIOLOGIJO - GIMNAZIJA FRANCA MIKLOSICA LJUTOMER - - - EUR 158 994,50 - - - Science for Life - - - EUR 158 994,50 - - - Slovenia - Slovenia - Slovenia - Slovenia - Slovenia - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - - Main objectives of the SciFe proposal is to bring researchers to the general public, to inspire youngster to embark on scientific careers, to increase awareness of importance of research and innovation activities, with a view - to supporting the public recognition of researchers creating an understanding of the impact of researchers' work on citizen's daily life. For that purpose the awareness campaign (AC) to convey messages under the slogan “Science for Life” will be used - in 2016 and 2017. On Fridays 30.9.’16 and 29.9.’17 SciFe events will be organized with renewed programs in festive and fun atmosphere in Ljutomer, Maribor, Brežice, Ljubljana, Koper, Izola and Nova Gorica. All SciFe events’ activities aim at offering - the public at large an opportunity to cooperate in fascinating experiments, demonstrations, observations etc., to socialize and have fun with researchers in a relaxed atmosphere. The program is appropriate for public in general, regardless their - scientific program and especially designed for youngest. SciFe programs’ red line is contribution of science to life in various aspects. The »European corner« will be prepared in the heart of every RN location: the visitors will be offered - information on EC’s various actions and programs, EU material, “the Charter and the Code”, information how young people can become researchers and Framework Program witness’s experiences. Intensive awareness campaign is designed according to its main - target. The rich communication mix includes active engagement of the young people through the public call targeting primary and secondary schools. Last but not least, the impact assessment will focus to measure the success and the impact of SciFe - activities. All that will be achieved through consortium management of all WPs and harmonised communication mix with general public which takes into account existing recognition of the RN event in certain region and its number of inhabitants. - - 2017-11-30, closed project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.5."> - - - MSCA-NIGHT-2016 - European Researchers' Night - - - CSA - Coordination and support action - - - Slovenia - - - SciFe - - - H2020-MSCA-NIGHT-2016 - - - 722990 - - - - - THE UNIVERSITY OF WARWICK - - - EUR 183 454,80 - - - Sustainable steel braced frame for multi-hazard mitigation - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Modern societies need building infrastructure that is designed and maintained according to high sustainability and resilience standards. Sustainability in construction can be realized with demountable (easy to deconstruct) - structures that enable change of the building geometry (adaptability) and reuse of materials and structural members at the end of the building life. Resilience can be realized with structures that can be easily repaired, if damaged, so that building - service can be restored within an acceptable short, if not immediate, time after extreme loading conditions. Moreover, the need to design structures against multiple natural (e.g. earthquakes) and man-made (e.g. bomb blast) hazards has been - recognized. The goal of the project is to address the aforementioned urgent societal needs by developing a novel steel concentric braced frame (CBF) that can, for the first time, simultaneously achieve the following overall objectives: (a) - Sustainability in construction, (b) Enhanced progressive collapse resistance and reparability against a sudden loss of column due to bomb blast; and (c) Easy inspection and repair of damage to allow rapid return to building use and occupation after - strong earthquakes. - - 2017-08-30, closed project - - - 2015-08-31 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SustBracedMHaz - - - H2020-MSCA-IF-2014 - - - 654424 - - - - - LUNDS UNIVERSITET - - - EUR 173 857,20 - - - Next generation nanowire solar cells - - - EUR 173 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - Nanowire solar cells are an innovative and promising way to further reduce the cost of photovoltaic electricity for terrestrial applications. Accordingly, the ultimately goal of this project is to develop a multi-junction - solar cell composed of an array of III-V nanowire subcells, electrically connected to a state-of-the-art Si solar cell. In order to do so, two different epitaxial techniques will be used to accomplish the epitaxial growth of the nanowires: standard - MOVPE growth and the ground-breaking technology of Aerotaxy. Then, the nanowires will be embedded in a polymer and transferred to a Si substrate. - - - 2017-07-31, closed project - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - NEXTNANOCELLS - - - H2020-MSCA-IF-2014 - - - 656208 - - - - - SPECTROSWISS SARL - SPECTROSWISS SARL - - - EUR 150 000 - - - Precision mass spectrometry to leverage applications in life and environmental sciences - - - EUR 150 000 - - - Switzerland - Switzerland - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The unbeatable performance leaders in molecular analysis of biological and environmental samples are the Fourier transform mass spectrometers (FTMS): Orbitrap FTMS and ion cyclotron resonance (FT-ICR MS). However, even FTMS - approaches suffer from performance limitations when facing the molecular complexity of samples in modern applications. The primary reasons for these limitations are the space charge effects – strong Coulombic interactions of many ions oscillating in - the trapping devices. Applications suffering from space charge affects include those with (i) significant fluctuation of incoming ion currents; (ii) close spacing of molecular mass/charge ratios to be resolved; and (iii) high spectral dynamic range - of ion intensities. To address these performance challenges and as a result of the completed ERC Starting Grant, we propose to increase precision of mass measurements in FT-ICR MS by using the direct cyclotron frequency measurements instead of the - space charge-sensitive reduced cyclotron frequency measurements employed currently. We have confirmed the principal feasibility of FT-ICR MS at the cyclotron frequency on both types of commercial FT-ICR MS instruments on the lab level. The aim of our - PoC grant application is to realize the benefits of FT-ICR MS at the cyclotron frequency by developing and seamlessly integrating the laboratory-level innovation into commercial instruments at an industry-grade level to leverage life and - environmental sciences applications. The action plan includes: (i) enabling integration of prototype ICR mass analyzers into commercial FT-ICR MS instruments via feasibility studies and pilot projects; (ii) analyzing competitive advantages of the - project’s outcomes over existing products and workflows, with a focus on frequency (mass) precision increase; (iii) clarifying IPR position, strategy; and (iv) performing market analysis. - - 2018-12-31, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Switzerland - - - Precision4Life - - - ERC-2017-PoC - - - 768565 - - - - - UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN - UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN - - - EUR 148 805 - - - Antibiofouling Nanopatterned Electrospun Membranes for Nanofiltration Applications - - - EUR 148 805 - - - Ireland - Ireland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Water-stress in an increasing global problem and solutions such as water recycling and seawater desalination are now becoming a necessary part of the water infrastructure. The technology for the production of safe drinking is - increasingly dependent on these more diverse sources and a key enabling technology is membrane filtration. While membrane system are effective, the operating costs of such systems are hampered by fouling which increases the energy requirement for - process operation. The unique idea of this Proof of Concept is to develop an electrospun nanostructured membrane which can be integrated into water filtration technologies. The unique method of fabrication will produce an inherently antibacterial and - antibiofouling surface in a one-step process, cutting the number of manufacturing steps. This concept, when deployed commercially is expected to dramatically reduce the operating costs of membrane processes for water treatment. The commercialisation - route of the product will be through the patent protection and the licensing of the technology with a view to rapid commercialisation. - - 2019-03-31, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Ireland - - - ANEMONE - - - ERC-2017-PoC - - - 768731 - - - - - INSTALLATION EUROPEENNE DE RAYONNEMENT SYNCHROTRON - CONSORCIO PARA LA CONSTRUCCION EQUIPAMIENTO Y EXPLOTACION DEL LABORATORIO DE LUZ SINCROTRON - THE CYPRUS INSTITUTE - STIFTUNG DEUTSCHES ELEKTRONEN-SYNCHROTRON DESY - ELETTRA - SINCROTRONE TRIESTE SCPA - ISTITUTO NAZIONALE DI FISICA NUCLEARE - INSTRUCT ACADEMIC SERVICES LIMITED - SYNCHROTRON-LIGHT FOR EXPERIMENTAL SCIENCE AND APPLICATIONS IN THE MIDDLE EAST - Société civile SYNCHROTRON SOLEIL - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 957 323,75 - - - Opening Synchrotron Light for Experimental Science and Applications in the Middle East - - - EUR 2 100 823,75 - - - France - Spain - Cyprus - Germany - Italy - Italy - United Kingdom - Jordan - France - Switzerland - France - - - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Other - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Research Organisations - Research Organisations - - The OPEN SESAME project will ensure optimal exploitation of the Synchrotron light for Experimental Science and Applications in the Middle East (SESAME) light source. With this aim, OPEN SESAME has three key objectives: - - - 2019-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.3.1., H2020-EU.1.4.3.2."> - - - INFRASUPP-01-2016 - Policy and international cooperation measures for research infrastructures - - - CSA - Coordination and support action - - - France - - - OPEN SESAME - - - H2020-INFRASUPP-2016-1 - - - 730943 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 2 283 955 - - - Stratified turbulence and mixing processes - - - EUR 2 283 955 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - We propose to study turbulence and mixing in stably stratified fluid. Mixing is central to a wide range of questions from the heat uptake in the global ocean, the transport and dilution of pollutants in the atmosphere, the - efficient cooling of buildings, to the homogenising of products in the food industry. However, the mechanisms that are responsible and their physical and dynamical aspects are largely unknown, and it is not possible to predict mixing rates from a - knowledge of the overall flow and density fields. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - STAMP - - - ERC-2016-ADG - - - 742480 - - - - - KAROLINSKA INSTITUTET - KAROLINSKA INSTITUTET - - - EUR 2 413 449 - - - Mimicking liver disease and regeneration in vitro for drug development and liver transplantation - - - EUR 2 413 449 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The liver is a vital organ for synthesis and detoxification. The most significant liver diseases are hepatitis, non alcoholic fatty liver disease (NAFLD), non-alcoholic fatty liver steatohepatitis (NASH), carcinoma and - cirrhosis. An additional and important cause of liver injury is adverse drug reactions (ADRs). In particular NAFLD is the most common liver disease affecting between 20% and 44% of European adults and 43-70% of patients with type 2 diabetes, and is - one prime cause for chronic and end-stage liver disease, such as cirrhosis and primary hepatocellular carcinoma. - - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Sweden - - - HEPASPHER - - - ERC-2016-ADG - - - 742020 - - - - - WEIZMANN INSTITUTE OF SCIENCE - WEIZMANN INSTITUTE OF SCIENCE - - - EUR 150 000 - - - Producing hydrogen by water splitting - - - EUR 150 000 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This proposal describes a plan to prove the role of electrons’ spin in the photocatalyzed oxidation of water; reaction of two water molecules to form two hydrogen molecules and a single oxygen molecule in its triplet ground - state. We found that the catalyst performance is affected by its chiral symmetry, or lack thereof. It is well known that the electrochemical and photoelectrochemical splitting of water requires a high overpotential and that it can be changed by the - choice of catalyst; however, the origin of the overpotential was not fully understood. In addition, the artificial water splitting reaction is commonly hampered by the production of hydrogen peroxide, which reduces the hydrogen yield and acts as a - strong oxidation agent that can damage the electrochemical cell. The proposed studies will build on our new results which suggest that the chirality of the photoanode material can reduce the overpotential for water splitting and enhance the reaction - rate. We found that spin-polarized current causes a spin correlation between the two OH intermediates in the reaction. This spin correlation could both suppress production of hydrogen peroxide and enhance the formation rate of oxygen molecules in the - triplet state, improving water splitting efficiency. - - - 2018-12-31, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Israel - - - watersplit - - - ERC-2017-PoC - - - 764203 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 2 043 630 - - - Active and Driven Systems: Nonequilibrium Statistical Physics - - - EUR 2 043 630 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Active Matter systems, such as self-propelled colloids, violate time-reversal symmetry by producing entropy locally, typically converting fuel into mechanical motion at the particle scale. Other driven systems instead produce - entropy because of global forcing by external fields, or boundary conditions that impose macroscopic fluxes (such as the momentum flux across a fluid sheared between moving parallel walls). - - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - ADSNeSP - - - ERC-2016-ADG - - - 740269 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 2 362 230 - - - Star-Planet-Inner Disk Interactions (SPIDI): unveiling the formation and evolution of inner planetary systems - - - EUR 2 362 230 - - - France - France - - - Research Organisations - Research Organisations - - With more than 2,000 confirmed exoplanets discovered to date, and about 4,000 additional candidates, it is now widely accepted that nearly every star in the Galaxy hosts a planetary system. These systems greatly differs from - our Solar System: a vast majority of exoplanets revolves at a distance less than the Earth’s orbit (1 astronomical unit, 1 AU), and many orbit very close to their parent star indeed (<0.1 AU). These inner planets, with an orbital period less than - 100 days, are quite diverse, ranging from Earth-like to Jupiter-like. How do they form or migrate close their star is still an open issue. ALMA and VLT/SPHERE recently released spectacular images of circumstellar disks around young stars, which - exhibit large-scale structures (>10 AU), including rings, gaps, and spiral arms that presumably are the signposts of planet formation. Yet, as powerful as they are, imaging techniques are yet unable to probe the inner disk region. The goal of the - SPIDI project is to investigate the origin and evolution of inner planetary systems. Specifically, we will develop dynamical models of inner planets embedded in the accretion disk of young stars to investigate the physical processes that govern the - star-disk-planet interactions from 1 AU down to the stellar surface. From these models, we will then predict the observational signatures of disk-embedded inner planetary systems, and devise and implement observations that will allow us to detect - them. This can only be done indirectly through simultaneous time domain photometry, spectroscopy, spectropolarimetry, and interferometry. Combined with current results obtained on larger scales, the SPIDI project will thus yield a synthetic view of - nascent planetary systems, down to the inner edge of protoplanetary disks. It will bring clues to the origin of our own inner Solar System, and more generally, address the formation process and ubiquity of inner planetary systems throughout the - Galaxy. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - France - - - SPIDI - - - ERC-2016-ADG - - - 742095 - - - - - KOBENHAVNS UNIVERSITET - KOBENHAVNS UNIVERSITET - - - EUR 1 997 592,92 - - - Repair capacity and genome diversity in mammals - - - EUR 1 997 592,92 - - - Denmark - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Genome evolution is driven by the generation of diversity. In mammals, genome diversification occurs in germline during the specialised division (meiosis) in gametes, when chromosomes recombine and assort into new haploid sets - as they are passed from parent to offspring. Recently, the traditional view that genome diversification occurs exclusively in the germline has been challenged by findings that mutations in early embryos may cause predisposition to childhood cancers. - We are uniquely placed to explore genome diversification in the germline and early embryos due to our breakthroughs in developing single-cell genomics and reproductive technologies. - - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Denmark - - - ReCAP - - - ERC-2016-COG - - - 724718 - - - - - LUNDS UNIVERSITET - LUNDS UNIVERSITET - - - EUR 2 500 000 - - - Immunity in Ecology and Evolution: 'Hidden' costs of disease, immune function and their consequences for Darwinian fitness - - - EUR 2 500 000 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Eco-immunology targets one of the great challenges in biology and medicine - how the immune system has evolved to optimize protection and minimize immunopathology (incl. autoimmune) costs. A primary target of my proposal is to - study low-virulent pathogens causing mild infections, which for long have been considered harmless. Recent research suggests that this notion is false and that seemingly harmless pathogens entail delayed (‘hidden’) fitness costs. However, the - mechanisms mediating these costs are still unknown. I will experimentally test if accelerated telomere degradation is a causative mechanism through which small immune costs can accumulate and be translated into senescence and reduced Darwinian - fitness. Another key target is immune costs, which may be ‘hidden’ because of sexually antagonistic effects, and I will study how this may affect immune gene variation, immune costs and Darwinian fitness. These aspects are central for advancing our - understanding of the evolution of disease resistance and immune function, incl. immune over-reactions (autoimmunity). - - 2022-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Sweden - - - EcoImmuneCosts - - - ERC-2016-ADG - - - 742646 - - - - - UNIVERSITY OF NEWCASTLE UPON TYNE - UNIVERSITY OF NEWCASTLE UPON TYNE - - - EUR 1 995 677 - - - Who is that? Neural networks and mechanisms for identifying individuals - - - EUR 1 995 677 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Our social interactions and survival critically depend on identifying specific individuals to interact with or avoid (“who is that?”). Identifying individuals can be achieved by different sensory inputs, and by many accounts - any sensory input elicits a representation of an individual that somehow becomes transmodal or independent of any sensory system. However, how the brain achieves transmodal integration facilitating individual recognition remains a mystery: - Investigations in humans allowing direct access to site-specific neuronal processes are generally rare and have not focused on understanding neuronal multisensory integration for person recognition. Also, animal models to study the neuronal - mechanisms of related processes have only recently become known. I propose to use direct recordings of neuronal activity in both humans and monkeys during face- and voice-identification tasks, combined with site-specific manipulation of the sensory - input streams into the lateral anterior temporal lobe (ATL). The ATL brings together identity-specific content from the senses but the neuronal mechanisms for this convergence are entirely unknown. My core hypothesis is that auditory voice- or visual - face-identity input into key ATL convergence sites elicits a sensory-modality invariant representation, which once elicited is robust to degradation or inactivation of neuronal input from the other sense. The central aim is to test this in human - patients being monitored for surgery and to directly compare and link the results with those in monkeys where the neuronal circuit and mechanisms can be revealed using optogenetic control of neuronal responses. Analyses will assess neuronal dynamics - and sensory integration frameworks. This proposal is poised to unravel how the brain combines multisensory input critical for identifying individuals and cognitive operations to act upon. The basic science insights gained may inform efforts to - stratify patients with different types of ATL damage. - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - MECHIDENT - - - ERC-2016-COG - - - 724198 - - - - - KOBENHAVNS UNIVERSITET - - - EUR 212 194,80 - - - A Realizability Approach to Complexity Theory - - - EUR 212 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - "Complexity theory concerns fundamental questions on the mathematics of computer science about the amount of resources needed to run programs or solve problems. The ReACT project will build on recent work in realizability - models for linear logic to provide new characterizations of existing complexity classes. The end goal is to enable researchers to attack long-standing open problems in complexity theory by using mathematical techniques, tools and invariants from - operators algebras and dynamical systems. - - 2017-10-31, closed project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - ReACT - - - H2020-MSCA-IF-2014 - - - 659920 - - - - - MEDICAL RESEARCH INFRASTRUCTURE DEVELOPMENT AND HEALTH SERVICES FUND BY THE SHEBA MEDICAL CENTER - MEDICAL RESEARCH INFRASTRUCTURE DEVELOPMENT AND HEALTH SERVICES FUND BY THE SHEBA MEDICAL CENTER - - - EUR 2 457 500 - - - Transcriptomic m1A - a new key player in the epitranscriptome arena - - - EUR 2 457 500 - - - Israel - Israel - - - Research Organisations - Research Organisations - - Reversible epigenetic modifications regulate gene expression to define cell fate and response to environmental stimuli. Gene expression tuning by DNA and chromatin modifications is well studied, yet the effect of RNA - modifications on gene expression is only starting to be revealed. More than a hundred chemical modifications decorate RNAs, mainly non-coding ones, expanding their nucleotide vocabulary and mediating their diverse functions. Several modifications - were globally mapped in mRNA. Only two, N6-methyladenosine (m6A) and N1-methyladenosine (m1A) exhibit a distinct topology alluding to a functional role. We pioneered the identification of m6A that is located preferentially in distinct transcript - landmarks, mostly around stop codons and mediates transcript localization, splicing, decay and translation. We now identified m1A which decorates thousands of genes mainly in the start codon vicinity, upstream to the first splice site. Our - preliminary results indicate that m1A dynamically responds to environmental stimuli and plays a central role in translation regulation. The regulation and functions of m1A are still terra incognita. Our objectives are to identify m1A writers and - erasers, elucidate m1A readers and the mechanisms whereby m1A dictates downstream outcomes, particularly translation regulation. We will study m1A functions in response to physiologic stimuli and stress conditions in cells and animal models by - manipulation of the m1A deposition machinery. As epigenetic marks operate in a context-dependent concerted way we will map m1A marks concomitantly with m6A to decipher their interplay in regulating gene expression via a putative “epigenetic RNA - code”. The data obtained from parallel mapping of m1A and m6A at a single nucleotide and a single transcript resolution, will expose the interplay between these two mRNA modifications in the context of multilayer epigenetics. The study of m1A - circuits may identify targets amenable to therapeutic manipulations. - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Israel - - - m1ARNA - - - ERC-2016-ADG - - - 743168 - - - - - INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE - INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE - - - EUR 1 498 751,25 - - - Boosting Brain-Computer Communication with high Quality User Training - - - EUR 1 498 751,25 - - - France - France - - - Research Organisations - Research Organisations - - Brain-Computer Interfaces (BCIs) are communication systems that enable users to send commands to computers through brain signals only, by measuring and processing these signals. Making computer control possible without any - physical activity, BCIs have promised to revolutionize many application areas, notably assistive technologies, e.g., for wheelchair control, and human-machine interaction. Despite this promising potential, BCIs are still barely used outside - laboratories, due to their current poor reliability. For instance, BCIs only using two imagined hand movements as mental commands decode, on average, less than 80% of these commands correctly, while 10 to 30% of users cannot control a BCI at all. - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - BrainConquest - - - ERC-2016-STG - - - 714567 - - - - - HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF EV - HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF EV - - - EUR 150 000 - - - All-electrical analytic platform for digital fluidics - - - EUR 150 000 - - - Germany - Germany - - - Research Organisations - Research Organisations - - Prospective biosensing technologies will need to tackle the grand challenges arising from the global demographic changes. Among the most crucial tasks is the monitoring of food and environmental quality as well as the medical - diagnosis. Digital fluidics offers vast advantages in performing these tasks relying on tiny containers with reacting biochemical species and allowing massively parallelized assays and high throughput screening using optical detection approaches. - - - 2019-02-28, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2017-PoC - ERC-Proof of Concept - - - ERC-POC - Proof of Concept Grant - - - Germany - - - ANALYTICS - - - ERC-2017-PoC - - - 768584 - - - - - UNIVERSITY COLLEGE LONDON - UNIVERSITY COLLEGE LONDON - - - EUR 149 062 - - - Antibiotic intracellular delivery via virus-like carriers - - - EUR 149 062 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Taking inspiration from natural carriers, such as viruses, a new technology has been developed in our laboratories part of an ongoing ERC starting grant project, Molecular Engineering of Virus-like Carriers (MEViC). We created - synthetic viruses using polymers and thus safer materials. They are able of delivering high payload of specific drugs into cells with no detrimental effect. While testing for anticancer therapies, we identified a synthetic virus capable of targeting - almost exclusively macrophages. We performed preliminary work showing that this can be successfully applied to deliver antibiotics to rid of intracellular pathogens. This has now open a completely new possibility whereas we can expand our technology - for the treatment of several infections as well as to contribute to the ongoing efforts in tackling antibiotic resistance. - - 2018-12-31, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - AIDViC - - - ERC-2016-PoC - - - 754704 - - - - - UNIVERSITA DEGLI STUDI DI GENOVA - UNIVERSITA DEGLI STUDI DI GENOVA - - - EUR 2 396 643,75 - - - Detection, simulation, modelling and loading of thunderstorm outflows to design wind-safer and cost-efficient structures - - - EUR 2 396 643,75 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Wind actions are crucial for the safety and cost of structures. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Italy - - - THUNDERR - - - ERC-2016-ADG - - - 741273 - - - - - RIJKSUNIVERSITEIT GRONINGEN - RIJKSUNIVERSITEIT GRONINGEN - VRIJE UNIVERSITEIT BRUSSEL - - - EUR 2 499 418,75 - - - Family ties that bind: A new view of internal migration, immobility and labour-market outcomes - - - EUR 2 499 418,75 - - - Netherlands - Netherlands - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Internal migration (long-distance moves within national borders) is generally assumed to be beneficial to individuals and households. This FamilyTies project has been designed to make a decisive contribution to a much more - comprehensive explanation of internal migration and its labour-market outcomes than current, mainly economic, explanations have achieved thus far. It introduces a novel perspective on internal migration and immobility, which focuses on the role of - family outside the household in deciding on whether and where to relocate, and which takes into account contemporary family complexity: the family ties perspective. The aim is to identify the role of family ties in internal migration, immobility and - labour-market outcomes. The objectives are: - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Netherlands - - - FamilyTies - - - ERC-2016-ADG - - - 740113 - - - - - TTY-SAATIO - TTY-SAATIO - - - EUR 150 000 - - - Pre-Commercialisation of Sound Recognition for Surveillance Applications - - - EUR 150 000 - - - Finland - Finland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Audio communication is a major tool for businesses to maintain their competitiveness in the global market. This market is expected to treble by 2020 to $2.145 billion and creates a great demand for novel ideas, such as - acoustic pattern recognition technologies. Similarly, the explosion in big data is calling for new data classification methods for improved data indexation and real-time monitoring of the data streams. - - - 2019-02-28, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Finland - - - SMARTSOUND - - - ERC-2016-PoC - - - 737472 - - - - - UNIVERSITY COLLEGE LONDON - UNIVERSITY COLLEGE LONDON - UNIVERSITY COLLEGE LONDON HOSPITALSNHS FOUNDATION TRUST - - - EUR 2 497 841 - - - Understanding cancer development in BRCA 1/2 mutation carriers for improved Early detection and Risk Control - - - EUR 2 497 841 - - - United Kingdom - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - Recent evidence demonstrates that cancer is overtaking cardiovascular disease as the number one cause of mortality in Europe. This is largely due to the lack of preventative measures for common (e.g. breast) or highly fatal - (e.g. ovarian) human cancers. Most cancers are multifactorial in origin. The core hypothesis of this research programme is that the extremely high risk of BRCA1/2 germline mutation carriers to develop breast and ovarian cancer is a net consequence of - cell-autonomous (direct effect of BRCA mutation in cells at risk) and cell non-autonomous (produced in distant organs and affecting organs at risk) factors which both trigger epigenetic, cancer-initiating effects. - - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - BRCA-ERC - - - ERC-2016-ADG - - - 742432 - - - - - ISTITUTO NAZIONALE DI FISICA NUCLEARE - HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF EV - Prisma Electronics ABEE - POLITECNICO DI MILANO - CLEVER OPERATION - UNIVERSITA DEGLI STUDI DI GENOVA - UNIVERSITA DI PISA - STOCKHOLMS UNIVERSITET - KUNGLIGA TEKNISKA HOEGSKOLAN - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSITA DEGLI STUDI DI PERUGIA - UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA - IMPEX HIGHTECH GMBH - EUROPEAN GRAVITATIONAL OBSERVATORY - UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II. - - - EUR 1 566 000 - - - NEw WindowS on the universe and technological advancements from trilateral EU-US-Japan collaboration - - - EUR 1 566 000 - - - Italy - Germany - Greece - Italy - France - Italy - Italy - Sweden - Sweden - France - Italy - Italy - Germany - Italy - Italy - - - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - - NEWS promotes the collaboration between European, US and Japanese research institutions in some key areas of fundamental physics. LIGO and Virgo collaborations have built the largest gravitational wave observatories and - exploit the propagation of light and spacetime to detect gravitational waves and probe their sources. The first observation of a signal from a merging black hole system has inaugurated the era of gravitational wave astronomy. The Large Area Telescope - collaboration operates a gamma-ray telescope onboard the Fermi Gamma Ray Space Telescope mission and has revolutionized our view of the gamma-ray Universe, by increasing the number of known sources, unveiling new classes of gamma-ray emitters, and - probing particle acceleration and electromagnetic emission in space with unprecedented detail. Fermi is the reference all-sky gamma-ray monitor for the follow-up searches for electromagnetic counterparts of gravitational wave sources. The - multimessenger astronomical observations will soon be enriched by X-ray polarization detectors. New-generation space telescopes will measure the polarization of X-rays from the cosmic sources and probe the laws of physics under extreme conditions of - gravitational and electromagnetic fields. A complementary approach to probe the Universe is provided by particle accelerators built in laboratories. FNAL will provide the cleanest probes for physics beyond the Standard Model of particle physics. The - Muon (g-2) experiment will measure the muon anomalous magnetic moment with unprecedented precision. Mu2e will search for the neutrinoless coherent muon conversion to an electron in the Coulomb field of a nucleus, which would be the unambiguous - evidence of new, unknown, physics. These endeavors require innovative detectors and cutting-edge technologies that NEWS will develop to open new “windows” in fundamental physics. - - 2021-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Italy - - - NEWS - - - H2020-MSCA-RISE-2016 - - - 734303 - - - - - HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH - HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH - - - EUR 1 498 175 - - - Mucosal Tolerance and Allergic Predisposition: Does it all start in the gut? - - - EUR 1 498 175 - - - Germany - Germany - - - Research Organisations - Research Organisations - - Currently, more than 30% of all Europeans suffer from one or more allergic disorder but treatment is still mostly symptomatic due to a lack of understanding the underlying causality. Allergies are caused by type 2 immune - responses triggered by recognition of harmless antigens. Both genetic and environmental factors have been proposed to favour allergic predisposition and both factors have a huge impact on the symbiotic microbiota and the intestinal immune system. - Recently we and others showed that the transcription factor ROR(γt) seems to play a key role in mucosal tolerance in the gut and also regulates intestinal type 2 immune responses. - - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - ALLERGUT - - - ERC-2016-STG - - - 716718 - - - - - CENTRO DE ESTUDOS SOCIAIS - CENTRO DE ESTUDOS SOCIAIS - - - EUR 1 915 381 - - - The politics of anti-racism in Europe and Latin America: knowledge production, decision-making and collective struggles - - - EUR 1 915 381 - - - Portugal - Portugal - - - Research Organisations - Research Organisations - - The main objective of POLITICS is to innovate knowledge on anti-racism that brings about a greater understanding of how historically rooted injustices are being challenged by institutions and grassroots movements. Considering - the centrality and mutual influence of Europe and Latin America in the global processes of racial formation, POLITICS will develop an inter-disciplinary and comprehensive approach towards two core goals: (a) the analysis of processes of knowledge - production about ‘race’ and (anti-)racism in the spheres of (inter)national governmental politics, State universities and grassroots movements; (b) the examination of diverse paths of denunciation and collective mobilisation against everyday racism - concerning police practice and representations in the mass media. - - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Portugal - - - POLITICS - - - ERC-2016-COG - - - 725402 - - - - - ECOLE POLYTECHNIQUE - ECOLE POLYTECHNIQUE - - - EUR 2 472 752 - - - Charting a New Horizon of Big and Fast Data Analysis through Integrated Algorithm Design - - - EUR 2 472 752 - - - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This proposal addresses a pressing need from emerging big data applications such as genomics and data center monitoring: besides the scale of processing, big data systems must also enable perpetual, low-latency processing for - a broad set of analytical tasks, referred to as big and fast data analysis. Today’s technology falls severely short for such needs due to the lack of support of complex analytics with scale, low latency, and strong guarantees of user performance - requirements. To bridge the gap, this proposal tackles a grand challenge: “How do we design an algorithmic foundation that enables the development of all necessary pillars of big and fast data analysis?” This proposal considers three pillars: - - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - France - - - BigFastData - - - ERC-2016-COG - - - 725561 - - - - - THE UNIVERSITY OF EXETER - THE UNIVERSITY OF EXETER - UNIVERSITY OF OTAGO - - - EUR 1 498 337 - - - The evolutionary ecology of bacterial immune mechanisms - - - EUR 1 498 337 - - - United Kingdom - United Kingdom - New Zealand - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Bacteria have a range of immune mechanisms, but it is unclear why this diverse armamentarium evolved. The most important immune mechanisms are (1) Surface Modification (SM) (2) Abortive infection (Abi) (3) Restriction - Modification (R-M) (4) CRISPR-Cas and (5) prokaryotic Argonaute (pAgo), all of which can occur as stand-alone mechanisms or in combination. The individual mechanisms differ in key aspects, such as their fitness costs (constitutive versus inducible), - specificity (indiscriminate versus specific), the recipient of the benefits (individual versus group), the speed of de novo resistance evolution (rapid versus slow), and heritability of immunity. Here I will take a combined in vitro and in vivo - approach to tease apart the variables that drive the evolution of these diverse stand-alone and integrated bacterial immune strategies in nature, and examine their associated co-evolutionary dynamics. I focus on three ecological variables that are - consistently important in host-symbiont co-evolution: (1) force of infection (2) spatial structure (3) presence of mutualists (plasmids). First, I will perform in vitro manipulations using Pseudomonas aeruginosa PA14 variants that carry either single - or multiple immune mechanisms. Next, I will sequence metagenomes, transcriptomes and viromes of microbial communities from environments that differ in ecological variables that are important in vitro, to examine their importance in vivo. Key - ecological mechanisms identified in the first two parts of the project will be used to guide mesocosm experiments to experimentally confirm that these mechanisms are the drivers of the observed patterns of resistance and co-evolution in nature. - Finally, I will share my data with mathematical biologists to generate theoretical models to predict and manipulate the evolution of bacterial immune mechanisms, which will facilitate tailored species protection in agriculture and industry. - - - 2021-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - EVOIMMECH - - - ERC-2016-STG - - - 714478 - - - - - UNIVERSITEIT GENT - UNIVERSITEIT GENT - - - EUR 1 427 625 - - - Photonics in Flatland: Band Structure Engineering of 2D Excitons in Fluorescent Colloidal Nanomaterials - - - EUR 1 427 625 - - - Belgium - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In PHOCONA we aim to develop a new class of highly fluorescent 2D and quasi-2D colloidal nanomaterials for solution-processed coherent light sources and ultrafast single-photon emitters. The 2D excitons are created in - suspended semiconductor nanoplates with a thickness below 5 nm, and transition-metal dichalcogenide monolayers. Prepared by colloidal chemistry and liquid-phase exfoliation, respectively, they take advantage of both quantum confinement through their - nanoscale dimensions, as well as dielectric confinement via the dielectric mismatch between nanomaterials and surrounding matrix. Via smart nanocrystal design, more specifically by exploiting novel synthesis methods that include asymmetric in-plane - confinement potentials, anisotropic crystal structures, and lattice strain-induced band structure modifications in core/shell heterostructures, the nanomaterials will be shaped toward efficient multiexciton and stimulated emission, as well as stable, - blinking-free single-photon emission. The intrinsic 2D exciton properties will be further modified toward ultrafast exciton recombination by coupling the nanomaterials to small mode-volume plasmonic nanocavities, hereby placing them in a local photon - density-of-states that will lead to a strong Purcell enhancement. The realization of cost-effective, energy-efficient and highly flexible light emitters, which can be synthesized and processed via methods that are scalable to large areas and volumes, - forms an important milestone in the ongoing development of optical and quantum communications technology, as well as new lighting and display applications. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Belgium - - - PHOCONA - - - ERC-2016-STG - - - 714876 - - - - - FUNDACION PRIVADA INSTITUTO DE SALUD GLOBAL BARCELONA - - - EUR 158 121,60 - - - Acclimatization scenarios and early warning system of temperature-related mortality in Europe - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - The research proposed in this project is focused on the study of one of the most challenging and potentially-dangerous impacts of climate in European societies: the mortality associated with environmental temperatures in the - current context of global warming. The research objectives of the proposal are (i) the description of the dependency between counts of deaths and climate variables contributing to increased body stress, (ii) the inference of future projections of - mortality under scenarios of increased greenhouse gas concentrations, (iii) the study of the effect of adaptation measures on these projections, and (iv) the development of an early warning system of mortality risk as a climate service for European - societies. During the implementation of all these objectives, the main results and conclusions of the research will be communicated to the general public and disseminated in specialized circles within and outside the research field. The research and - methodology here proposed are clearly innovative, given that the project will integrate climate information and tools with unprecedented high-quality mortality and sociodemographic data in a multidisciplinary approach that will take into account the - degree of adaptability of human societies and individuals to scenarios of increased greenhouse gas concentrations in the atmosphere. In this sense, the design of the proposal clearly fits into the main guidelines and objectives defined by the - European Commission in the work programme of the initiative Horizon 2020, which contributes to the generation of climate services that provide useful guidance to health care systems, governments and policy makers throughout Europe. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Spain - - - ACCLIM - - - H2020-MSCA-IF-2016 - - - 737480 - - - - - KAROLINSKA INSTITUTET - UNIVERSITE DE BORDEAUX - UNIVERSITA DEGLI STUDI DI MILANO - DEUTSCHES ZENTRUM FUR NEURODEGENERATIVE ERKRANKUNGEN EV - Janssen Pharmaceutica NV - AXON NEUROSCIENCE SE - - - EUR 3 846 736,44 - - - Synaptic Dysfunction in Alzheimer Disease - - - EUR 3 846 736,44 - - - Sweden - France - Italy - Germany - Belgium - Slovakia - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Given an overwhelming increase of dementia costs and an aging population, there is an urgent need for finding novel therapies for Alzheimer Disease (AD). We are, however, facing a large number of failed clinical trials and a - retraction of the nervous system R&D programmes from several big pharmaceutical companies. Increased collaboration between academia and the private sector is required to overcome this challenge. - - 2019-10-31, ongoing project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Sweden - - - SyDAD - - - H2020-MSCA-ITN-2015 - - - 676144 - - - - - VILNIAUS UNIVERSITETAS - - - EUR 130 779,60 - - - Spin Transport in Interacting Spin-Orbit Coupled Systems - - - EUR 130 779,60 - - - Lithuania - - - Higher or Secondary Education Establishments - - The physics of charge and spin transport is the basis of current consumer devices. Recent discoveries in solid-state physics have highlighted the importance of the coupling of the electron’s motion to its spin for transport - phenomena. However, our understanding of transport with this so-called spin-orbit coupling has been largely limited to non-interacting systems, even though the first experimental systems with well-controlled spin-orbit coupling and interactions are - already available. - - 2018-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Lithuania - - - SPINSOCS - - - H2020-MSCA-IF-2015 - - - 706839 - - - - - FUNDACIO CENTRE DE RECERCA EN SALUT INTERNATIONAL DE BARCELONA - FUNDACION PRIVADA INSTITUTO DE SALUD GLOBAL BARCELONA - LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE - PRINS LEOPOLD INSTITUUT VOOR TROPISCHE GENEESKUNDE - CORIS BIOCONCEPT SPRL - UNIVERZITA KARLOVA - BMD SOFTWARE LDA - THE UNIVERSITY OF WARWICK - INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 3 820 537,80 - - - Control of leishmaniasis, from bench to bedside and community - - - EUR 3 820 537,80 - - - Spain - Spain - United Kingdom - Belgium - Belgium - Czech Republic - Portugal - United Kingdom - France - Spain - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - - Leishmaniasis control is the topic for EUROLEISH-NET, a Marie Sklodowska-Curie – Innovative Training Network. Leishmaniasis is a neglected infectious disease and a major public health and veterinary problem that afflicts both - developing countries and Europe. The current technological and epidemiological advances underpin the necessity to develop training programmes aiming at developing new tools and strategies to control of leishmaniasis. An excellent group of academic - and non-academic institutions in Europe and abroad will host 15 PhD students who will receive training in this programme. The expertise and training that will be offered ranges from parasitology to molecular science, genetics, epidemiology and - strategic interventions. The 15 research projects designed encompass drug discovery, drug resistance, diagnostics and vaccine development, population genetics, vector control and integrated control programmes. The designated project supervisors have - proven track records of success in research and in training. The incorporation of trainee mobility into the network, together with the commitment, strong affiliations and technology transfer between the participants provide a highly synergistic - framework for success. The EUROLEISH-NET coordinators have proven experience in laboratory, field, administrative and financial management, supported by a meticulously planned series of meetings and diligent monitoring of the progression of each - researcher. We anticipate an extremely productive training and research output from EUROLEISH-NET. We expect to train the next generation of leading research scientists in this field, endowed with skills that are broadly and internationally - transposable. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Spain - - - EUROLEISH-NET - - - H2020-MSCA-ITN-2014 - - - 642609 - - - - - EUROPEAN SPACE AGENCY - ADVANCED COMPUTER SYSTEMS A.C.S. SPA - EXPERT SYSTEM IBERIA SL - TERRADUE SRL - METEOROLOGICAL AND ENVIRONMENTAL EARTH OBSERVATION SRL - NATURAL ENVIRONMENT RESEARCH COUNCIL - DEUTSCHES ZENTRUM FUER LUFT - UND RAUMFAHRT EV - ALMA SISTEMI SAS DI DI IORIO ALESSIO & C - EUROPEAN UNION SATELLITE CENTRE - ISTITUTO NAZIONALE DI GEOFISICA E VULCANOLOGIA - INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK - CONSIGLIO NAZIONALE DELLE RICERCHE - - - EUR 6 561 627 - - - European Virtual Environment for Research - Earth Science Themes - - - EUR 6 561 627,50 - - - France - Italy - Spain - Italy - Italy - United Kingdom - Germany - Italy - Spain - Italy - Poland - Italy - - - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Research Organisations - Research Organisations - - The EVER-EST project will enhance Research and Capacity Building in the Earth Science (ES) domain, by providing a generic Service Oriented-based Architecture Virtual Research Environment (VRE) tailored to the needs of the ES - community. The full range of both generic and ES data management specific services provided by EVER-EST will facilitate the dynamic approach to collaborative working and research. Scientist will be able to discover, access, process, share and - interoperate heterogeneous data, algorithms, results and experiences within and across their communities, including those in domains beyond Earth Science. Data providers will be able to monitor users experience and collect feedback through the VRE, - improving their capacity to adapt to end-user needs offering solutions to unlock scientist potentials and creativity. EVER-EST e-infrastructure will be validated by four Virtual Research Communities (VRC) covering different multidisciplinary working - ES domains: ranging from Sea Monitoring, to Natural Hazards (floods, weather, wildfires), Land Monitoring and Risk Management (volcanoes and seismic). Each of these VRC will use the VRE according to its own specific requirements for data, software, - best practices and community engagement. The VRE will leverage on the results of several FP7 projects which have produced state-of-the-art technologies for scientific data management and curation. Such capabilities will be enriched during the - EVER-EST project using the output of a second group of FP7 initiatives providing models, techniques and tools for the preservation of scientific methods and their implementation in computational forms such as scientific workflows. EVER-EST will - implement solutions for data publication, citation and trust. EVER-EST will provide the means to climb up existing peaks and obstacles to information sharing in Earth Science allowing research teams to collaboratively collect, manipulate and share - resources, allowing creation of new knowledge. - - 2018-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.3."> - - - EINFRA-9-2015 - e-Infrastructures for virtual research environments (VRE) - - - RIA - Research and Innovation action - - - France - - - EVER-EST - - - H2020-EINFRA-2015-1 - - - 674907 - - - - - ERASMUS UNIVERSITEIT ROTTERDAM - - - EUR 177 598,80 - - - The Aftermath of a Drug Withdrawal: Modeling Spillover Effects Across Countries and Across Categories - - - EUR 177 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - The pharmaceutical market is one of the most important industries in the global economy. Projections are that spending on medicines will grow to 1.2 trillion US$ in 2016. Marketing has an important impact in this - pharmaceutical industry, but has a particularly negative image. The growing pharmaceutical market increases the pressure for the regulators to approve new medicines and for firms the pressure to market their drugs to stay ahead of the competition. - These forces have contributed to the fact that over the past decade many drugs were approved too early, and the number of withdrawn drugs has doubled. A drug withdrawal is when a drug is taken off the market, because it is considered to be harmful - typically due to unexpected adverse effects (including deaths). Since the pharmaceutical market directly concerns population health, drug withdrawals can have disastrous consequences. - - - 2017-08-31, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - WITHDRAWAL AFTERMATH - - - H2020-MSCA-IF-2014 - - - 654862 - - - - - WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER - WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER - - - EUR 1 336 562,50 - - - Wayfinding Through Orientation - - - EUR 1 336 562,50 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Wayfinding is a task that we manage every day while going to work or on vacation. Although wayfinding research has gone through tremendous development, it suffers from fundamental shortcomings: State-of-the art wayfinding - research still adheres to the principles of turn-by-turn navigation. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - WayTO - - - ERC-2014-STG - - - 637645 - - - - - CITY UNIVERSITY OF LONDON - CHALMERS TEKNISKA HOEGSKOLA AB - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS - UNIVERSITAET STUTTGART - MITSUBISHI HITACHI POWER SYSTEMS EUROPE GMBH - KARLSRUHER INSTITUT FUER TECHNOLOGIE - UNIVERSITY COLLEGE LONDON - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - DELPHI AUTOMOTIVE SYSTEMS LUXEMBOURG SA - - - EUR 3 902 492,52 - - - Holistic Approach of Spray Injection through a Generalized Multi-phase Framework - - - EUR 3 902 492,52 - - - United Kingdom - Sweden - France - Greece - Germany - Germany - Germany - United Kingdom - United Kingdom - Luxembourg - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Development of fuel injection equipment (FIE) able to reduce pollutant emissions from liquid-fueled transportation and power generation systems is a top industrial priority in order to meet the forthcoming EU 2020 emission - legislations. However, design of new FIE is currently constrained by the incomplete physical understanding of complex micro-scale processes, such as in-nozzle cavitation, primary and secondary atomization. Unfortunately, today’s computing power does - not allow for an all-scale analysis of these processes. The proposed program aims to develop a large eddy simulation (LES) CFD model that will account for the influence of unresolved sub-grid-scale (SGS) processes to engineering scales at affordable - computing time scales. The bridging parameter between SGS and macro-scales flow processes is the surface area generation/destruction occurring during fuel atomisation; relevant SGS closure models will be developed through tailored experiments and DNS - and will be implemented into the LES model predicting the macroscopic spray development as function of the in-nozzle flow and surrounding air conditions. Validation of the new simulation tool, currently missing from today’s state-of-the-art models, - will be performed against new benchmark experimental data to be obtained as part of the programme, in addition to those provided by the industrial partners. This will demonstrate the applicability of the model as an engineering design tool suitable - for IC engines, gas turbines, fuel burners and even rocket engine fuel injectors. The proposed research and training programme will be undertaken by 15ESRs funded by the EU and one ESR funded independently from an Australian partner; ESRs will be - recruited/seconded by universities, research institutes and multinational fuel injection and combustion systems manufacturers that will represent in the best possible way the international, interdisciplinary and intersectoral requirements of the - Marie Curie Action guidelines. - - 2019-10-31, ongoing project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - HAoS - - - H2020-MSCA-ITN-2015 - - - 675676 - - - - - THE UNIVERSITY OF NOTTINGHAM - - - EUR 195 454,80 - - - Sputtering-deposition of metallic nanoparticles onto chiral ionic liquids andapplications in enantioselective hydrogenation - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The production of fine chemicals, such as chiral molecules, is one of the main applications of the chemical industry. However, any new process developed should be environmentally sound. Metallic nanoparticles (MNPs) have - attracted a large interest as catalytic materials due to their small size and high surface to bulk metal ratio, which leads to a greater catalytic activity. These catalysts are easily recyclable, although stabilizing agents are required to prevent - agglomeration. In this context, ionic liquids (ILs), salts with melting point <100 ºC, can act both as stabilizers and as solvents. Moreover, MNPs may be immobilized in this medium, allowing the separation of the products and the subsequent - recycling of the system. However, ILs are not “innocent” media and can impose a high degree of directionality over the substrates. The employment of chiral ILs adds a new advantage: its potential use in asymmetric catalysis to induce the formation of - chiral products. In this project we will merge the asymmetric properties of newly synthesized ILs with the catalytic activity of MNPs. Instead of classical chemical methods, MNPs in ILs will be obtained by sputtering-deposition (SD), an innovative - physical technique which enables the fast synthesis of clean MNPs, avoiding the use of organic solvents and reducing agents. In contrast to other physical techniques, the SD of MNPs onto ILs allows the control of the size and shape of MNPs by the - appropriate tuning of the sputtering conditions. These three concepts (MNP, chiral IL and SD) converge into the main aim of this project: The development of a novel chiral catalytic system based on MNPs prepared by SD onto chiral ILs for asymmetric - hydrogenation reactions. SDchirnanocat will contribute to broaden the fellow competencies and will place him in an excellent position to start an independent career. - - 2018-07-31, ongoing project - - - 2016-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SDchirnanocat - - - H2020-MSCA-IF-2015 - - - 704710 - - - - - HOSPITAL UNIVERSITARIO DE FUENLABRADA - HOSPITAL UNIVERSITARIO DE FUENLABRADA - FUNDACION CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III - - - EUR 2 498 687,50 - - - Integrating Genomics and Avatar Mouse Models to Personalize Pancreatic Cancer Treatment - - - EUR 2 498 687,50 - - - Spain - Spain - Spain - - - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - - The prognosis of patients with metastatic pancreatic cancer (PDAC) is very poor. Recent studies have started to elucidate the genetic landscape of this disease to show that PDAC is a genetically complex, unstable, and - heterogeneous cancer. However, in-depth analysis of individual patient genomes couple with personalize Avatar mouse models is providing highly effective therapeutic opportunities for the individual patient. Thus, metastatic PDAC appears a candidate - disease to implement a genomics-base, personalized treatment approach. In this project, we will conduct an open label, multicenter, randomized phase III study in patients with standard of care resistant metastatic pancreatic cancer aiming to test the - hypothesis that an integrated personalized treatment approach improves survival compare to a conventional treatment. Patients randomized to the personalize treatment arm will undergo a biopsy of a metastatic lesion to perform a targeted genome - analysis using next generation sequencing. In addition, we will generate a personalize Avatar mouse model from the same patient. We will employ sophisticated bioinformatic analysis as well as mining of drug response-genetic databases to select, for - each individual patient, candidate therapeutic targets that will be experimentally tested in the patient´s Avatar model to select the most effective regimen that will ultimately applied to the patient. In addition, based on the genomic data, we will - design an individualized monitoring plan for each patient using BEAMing technology to monitor circulating levels of mutated genes. Furthermore, with a discovery goal, we will perform in depth genomic analysis of metastatic PDAC lesions in this cohort - of clinically well-annotated patients with Avatar mouse models for therapeutic validation. Overall we expect this work will contribute to our understanding of PDAC and will favourably impact the treatment of this dismal cancer. - - 2020-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Spain - - - AVATAR - - - ERC-2014-ADG - - - 670582 - - - - - FORSCHUNGSVERBUND BERLIN EV - FORSCHUNGSVERBUND BERLIN EV - - - EUR 1 996 500 - - - In-cell NMR monitoring of alpha-Synuclein aggregation in neuronal cells - - - EUR 1 996 500 - - - Germany - Germany - - - Research Organisations - Research Organisations - - Intracellular aggregation of the human amyloid protein alpha-synuclein is causally involved in Parkinson’s disease, a debilitating neurodegenerative disorder. The goal of this project is to combine low-resolution, - fluorescence-imaging methods with high-resolution in-cell NMR and EPR spectroscopy techniques to derive macroscopic and microscopic insights into alpha-synuclein aggregate structures directly in neuronal cells. - - - 2020-10-31, ongoing project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - NeuroInCellNMR - - - ERC-2014-CoG - - - 647474 - - - - - CHALMERS TEKNISKA HOEGSKOLA AB - - - EUR 185 857,20 - - - Distributed storage based on sparse-graph codes - - - EUR 185 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - The recent years have witnessed the explosion of services and applications such as email, cloud computing, social and media networks, and video sharing. The grand challenge is to store, process and transfer this massive amount - of data. According to recent estimates, the data to be stored grows at a rate of 45% per year, a factor of 40 by 2024. Data centers typically employ a collection of cheap devices/nodes, which are connected forming a so-called distributed storage (DS) - system, where a central server keeps track of where each file is stored and performs all network operations. Every day, knowingly or unknowingly people connect to various private and public DS systems. It is nowadays accepted that current DS systems - cannot face the unabated growing of digital data volume. Nextgeneration storage systems desperately need new technologies to improve their robustness to node failures, storage efficiency, complexity, and cost efficiency, in order to sustain the - information revolution of modern societies. This project addresses the challenges above using modern coding theory and optimization theory. Our focus is on the application of sparse-graph erasure correcting codes to large DS networks. The proposed - project falls into the category of fundamental research, but it is driven by practical concerns, and we expect our findings to give new and relevant insights for the design of practical coding schemes for next-generation DS systems. - - 2017-04-30, closed project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - DISC - - - H2020-MSCA-IF-2014 - - - 658785 - - - - - LANCASTER UNIVERSITY - MEDIZINISCHE UNIVERSITAET WIEN - POLITECNICO DI TORINO - INSTITUT CURIE - Bayer AG - UNIVERSITAET BREMEN - Janssen Pharmaceutica NV - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - - - EUR 3 108 939,48 - - - Improving Design, Evaluation and Analysis of early drug development Studies - - - EUR 3 108 939,48 - - - United Kingdom - Austria - Italy - France - Germany - Germany - Belgium - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - - Drug development is a long and costly process which suffers from the major shortcoming that frequently failure is often only determined during the final stage. Recently, it has been recognised that more care needs to be taken - during the early stages of development to avoid going into lengthy and costly confirmatory studies with ineffective or harmful treatments. To achieve this goal it is essential to implement efficient methods for the design and analysis of such early - development studies. The expertise in this area is, however, limited at the moment and adequate methodology is only partially available. Using a cross-sectorial, transnational approach, the IDEAS network brings together leading public and private - sector researchers in the field with ample experience in training to educate, promote and support the future leaders in medical statistics in general and in the design and analysis of early developmental studies in particular. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - IDEAS - - - H2020-MSCA-ITN-2014 - - - 633567 - - - - - HELSINGIN YLIOPISTO - HELSINGIN YLIOPISTO - KOC UNIVERSITY - - - EUR 1 497 160 - - - Deciphering and reversing the consequences of mitochondrial DNA damage - - - EUR 1 497 160 - - - Finland - Finland - Turkey - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Mitochondrial DNA (mtDNA) encodes several proteins playing key roles in bioenergetics. Pathological mutations of mtDNA can be inherited or may accumulate following treatment for viral infections or cancer. Furthermore, many - organisms, including humans, accumulate significant mtDNA damage during their lifespan, and it is therefore possible that mtDNA mutations can promote the aging process. - - 2020-03-31, ongoing project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Finland - - - RevMito - - - ERC-2014-STG - - - 637649 - - - - - UNIVERSIDADE DE AVEIRO - UNIVERSITAET DUISBURG-ESSEN - SCIENCE AND TECHNOLOGY FACILITIES COUNCIL - VILNIAUS UNIVERSITETAS - HELMHOLTZ-ZENTRUM GEESTHACHT ZENTRUM FUR MATERIAL- UND KUSTENFORSCHUNG GMBH - SMALLMATEK - SMALL MATERIALS AND TECHNOLOGIES LDA - - - EUR 814 500 - - - TUneable Multiferroics based on oxygen OCtahedral Structures - - - EUR 814 500 - - - Portugal - Germany - United Kingdom - Lithuania - Germany - Portugal - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The main objective of the project is development of new lead-free multiferroic materialshe for prospective application in forms of films and/or arranged layers in which the cross-coupling (magnetic-dipolar-elastic) can be - tuned by both internal and external factors. This objective is to be achieved through preparation, investigation, and optimization of two kinds of Bi-containing oxygen-octahedral (BCOO) systems with paramagnetic ions involved: metastable perovskites - and layered double hydroxides (LDHs). The characteristic feature of such materials is a possibility of supplementary control parameters in addition to temperature and external electric/magnetic field. Polarization in such metastable perovskites is - easily switched by application of external pressure (or stress in the case of films). Electric and magnetic characteristics of BCOO LDHs are tuned through appropriate anion exchanges. It makes these characteristics dependent on environment - conditions: humidity, pH, and presence of specific anion species. The BCOO materials of both mentioned groups are of interest as new and unusual multiferroics. No LDH materials have been considered as potential multiferroics so far, while the - metastable BCOO materials proposed in this project have not been obtained before. Besides, a tuneability and high sensibility of their properties to external impacts make them promising for applications in sensors. Exploration and development of such - materials require consolidation of specialists of complementary expertise in Physics, Chemistry, and Materials Science, with access to and skills in using specific and unique equipment and facilities. Therefore, formation of an interdisciplinary - network of teams with different scientific culture and ensuring the effective knowledge & expertise transfer is important objective of the project. Advance in development of the BCOO multiferroics has potential market opportunities for R&D - SME involved in this project. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Portugal - - - TUMOCS - - - H2020-MSCA-RISE-2014 - - - 645660 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 158 121,60 - - - Nano-OptoMechanical Systems for Biological Sensors - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - The emergence of antibiotic resistance is one of the major challenges in microbiology and medicine today. Early identification of the pathogens causing an infection and the rapid identification of antibiotic resistance is - critical to provide the most effective drugs to the patient and to avoid costly and inefficient treatments that can potentially lead to the development of further resistances. This project proposes application of nano-optomechanical disk resonators - to face this challenge. We expect to achieve ultra-sensitive and ultrafast gene-based pathogen detection with subzeptogram (10-21g) mass resolution, beating current techniques. The development of arrays of 100s of microdrum devices per chip will - weigh complementary DNA strands to those immobilized on the microdrum surface, so tens of different pathogens in a sample can be identified, along with antibiotic resistances, which are also marked by mutations. The devices will be challenged with a - proof-of-principle application to identify sepsis-causing pathogens from blood samples and their resistance to the most commonly used antibiotics. The proposed devices provide a large binding area to reduce the analysis time while preserving extreme - sensitivity, down to a few biomolecules (DNA strands). We will be able to screen for tens of different pathogens per chip, with sensitivity good enough to target early infection stages from a standard blood extraction. This multidisciplinary and - intersectorial project promotes the collaboration of well-recognized academic research groups expert in the optomechanics field and in the development of novel biosensing tools, a clinical laboratory and an industrial partner, pursuing to generate - greater economic and social impact; as well as a highly effective training program for the benefit of the researcher. - - 2018-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - NOMBIS - - - H2020-MSCA-IF-2015 - - - 703354 - - - - - UNIVERSITA DEGLI STUDI DI CAGLIARI - - - EUR 168 277,20 - - - Catastrophic Failure in Flexural Lattice Problems - - - EUR 168 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - Currently, there is a vast amount of research activity taking place into the development of new materials having unconventional properties and the respective technologies have been opening new eras through various applications - for society. This new generation of materials, or metamaterials, have led to interesting physical properties previously thought impossible such as cloaking, negative refraction and materials that contract when heated. Most of those properties are - realised in the dynamic response of the material. However, in these dynamic processes uncertainty remains as to whether these metamaterials undergo feasible deformations, remaining intact. Research into the latter is limited. Understanding this - phenomenon is important in developing new metamaterials. Additionally it is crucial, for example, in larger structures such as multi-span bridges, pipelines and skyscrapers exposed to earthquakes and terrorist attacks, regularly faced in Europe and - their effects can be catastrophic to human life. - - 2019-09-13, ongoing project - - - 2017-09-14 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - CAT-FFLAP - - - H2020-MSCA-IF-2016 - - - 747334 - - - - - VILNIAUS UNIVERSITETAS - - - EUR 130 779,60 - - - Eat me microglia: lipid scrambling as a signal for synaptic pruning - - - EUR 130 779,60 - - - Lithuania - - - Higher or Secondary Education Establishments - - The development of the nervous system is associated with the generation of excess neuronal synapses that is followed by their tightly controlled removal, a process known as synaptic pruning. In the primate cortex, for example, - 70% of connections are selectively lost within the first six months of life. Why are so many synapses lost, what determines which synapses are eliminated, what are the molecular mechanisms involved, and what are the consequences of not getting it - right? Recently, several studies have presented microglial phagocytosis as a mechanism for synapse elimination. Neural activity plays a role in synaptic pruning, but the neuronal “eat-me” signals that mediate phagocytic recognition and engulfment of - synapses remain to be identified. We hypothesize that cell surface exposure of the lipid phosphatidylserine (PtdSer) is a key “eat-me” signal for synaptic pruning during development. Therefore we aim to define the role of PtdSer in synapse-microglia - interaction and to assess the morphological, circuit maturation and behavioural effects of impaired PtdSer exposure in phospholipid scramblase-deficient brains. We propose to use novel custom-made tool to observe PtdSer exposure without interfering - with PtdSer-dependent cellular interactions and two mouse models with disrupted PtdSer exposure to study how PtdSer contributes to circuit refinement. The identification of an “eat-me” signal will shed the light on what distinguishes synapses - destined to be eliminated from those that survive and will be the first step in understanding why the majority of synapses are turned over during brain development before the final connectome emerges. As aberrant brain wiring during development is - known to be defective in a wide range of neurodevelopmental disorders, understanding how circuits are formed and refined during developmental period will be critical to understand their aetiology and initiate the development of the therapy targeting - molecular mechanisms of disease. - - 2018-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Lithuania - - - LIPSYNING - - - H2020-MSCA-IF-2015 - - - 705452 - - - - - UNIVERSITE DE LAUSANNE - - - EUR 175 419,60 - - - Molecular evolution in the double-clonal longhorn crazy ant - - - EUR 175 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - The divergent selective pressures experienced by females and males often lead to the evolution of dramatic morphological, physiological and behavioural differences. Social insects hold a special place for understanding the - evolution of phenotypic differences, because one sex at least is subdivided into morphologically distinct reproductive and non-reproductive (worker) castes. This research program will investigate the molecular mechanisms governing the evolution of - sex (male vs female) and caste (queen vs worker) differences by studying the remarkable longhorn crazy ant Paratrechina longicornis. This species has evolved an unusual genetic system, whereby queen, male and worker phenotypes do not only result from - gene expression differences, but also possess different genetic makeups. Under this system, the genomes of queens and males no longer recombine and evolve as separate entities similar to sex chromosomes. Queens are clones of their mother, males are - clones of their father, and sterile workers are produced sexually through the union of queen and male genomes. The MELCA project proposes to take advantage of this double-clonal system to study how selection shapes the evolution and expression of - genes involved in phenotypic differences. We will sequence the genomes and transcriptomes of double-clonal queens, males, and workers, and link patterns of gene expression with changes in rates of molecular evolution to test predictions regarding the - nature of selection acting on genes involved in sex and caste differences. First, we will investigate the effects of the double-clonal system on patterns of sex-biased and allele-biased gene expression. Second, we will determine if this system leads - to differences in rate of evolution for genes with sex or caste functions. - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - MELCA - - - H2020-MSCA-IF-2016 - - - 750766 - - - - - UNIVERSITETET I BERGEN - - - EUR 208 400,40 - - - Modelling Complex Networks Through Graph Editing Problems - - - EUR 208 400,40 - - - Norway - - - Higher or Secondary Education Establishments - - The goal of the PROXNET project, which will be realised during the mobility of Christophe Crespelle in the Algorithms group of Bergen, is to open a new way for analysing, modelling and managing complex networks, through graph editing problems. - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Norway - - - PROXNET - - - H2020-MSCA-IF-2016 - - - 749022 - - - - - UNIVERSIDAD DE ZARAGOZA - - - EUR 257 191,20 - - - Wearable Cardiorespiratory Monitor - - - EUR 257 191,20 - - - Spain - - - Higher or Secondary Education Establishments - - The research topic of WECARMON deals with biomedical signal processing, specifically, the analysis of electrocardiogram (ECG) signals for cardiorespiratory system assessment. WECARMON’s main objective is to develop novel - system for early non-invasive detection of clinical destabilizations of patients with chronic respiratory diseases, e.g., chronic obstructive pulmonary disease (COPD) and asthma. Its innovative nature is based on two main tools: 1) a long-term - (months) wearable ECG device which uses dry electrodes which causes no skin irritation and which are placed in a left leadless armband, and 2) signal processing techniques for estimating respiratory rate and volumes from ECG which are robust against - artefacts generated by movements during daily life. - - 2020-10-08, ongoing project - - - 2017-10-09 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Spain - - - WECARMON - - - H2020-MSCA-IF-2016 - - - 745755 - - - - - UNIVERSITAT DE GIRONA - UNIVERSIDAD DE MURCIA - FUNDACIO CATALANA PER A LA RECERCA I LA INNOVACIO - FUNDACIÓN SÉNECA-AGENCIA DE CIENCIA Y TECNOLOGÍA DE LA REGIÓN DE MURCIA - CONSORCIO PARA LA CONSTRUCCION, EQUIPAMIENTO Y EXPLOTACION DEL CENTRO NACIONAL DE INVESTIGACION SOBRE LA EVOLUCION HUMANA - FUNDACION CANARIA PARQUE CIENTIFICO TECNOLOGICO DE LA UNIVERSIDAD DE LAS PALMAS DE GRAN CANARIA - UNIVERSIDAD DE OVIEDO - CONSEJERIA DE FOMENTO Y MEDIO AMBIENTE - JUNTA DE CASTILLA Y LEON - CONSORCIO PARA LA CONSTRUCCION EQUIPAMIENTO Y EXPLOTACION DEL LABORATORIO DE LUZ SINCROTRON - BIOCOMUNICA'T - INSTITUT DE RECERCA BIOMEDICA DE LLEIDA FUNDACIO PRIVADA DOCTOR PIFARRE - UNIVERSIDAD DE EXTREMADURA - FUNDACION MUSEO DE LA CIENCIA DE VALLADOLID - UNIVERSIDAD DE CANTABRIA - - - EUR 180 000 - - - European Researchers' Night: Researchers' For a Better Future - - - EUR 345 040 - - - Spain - Spain - Spain - Spain - Spain - Spain - Spain - Spain - Spain - Spain - Spain - Spain - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - Other - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Other - Research Organisations - Higher or Secondary Education Establishments - Other - Higher or Secondary Education Establishments - - The OurFuture: Researchers For a Better Future proposal consists in a two years proposal with different activities that are deeply related. The first activity consists of twelve main Events on the 26th September 2014 and 25th - September 2015, organised by five universities, 3 public foundations, one scientific association, one autonomic government and a scientific installation around Spain as well as a Science Museum. A second activity consists on a Drawing Competition, - which will be performed before and after the both events. Also special emphasis will be done on the 2.0 tools, using games and videos edited in the previous edition of European Researchers’ Night (ERN). These tools, together with the Drawing - Competition, will be used to disseminate Friday Event Activities. - - - 2015-10-31, closed project - - - 2014-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.5."> - - - MSCA-NIGHT-2014 - European Researchers' Night (NIGHT) - - - CSA - Coordination and support action - - - Spain - - - OurFuture - - - H2020-MSCA-NIGHT-2014 - - - 633243 - - - - - UNIVERSITY COLLEGE LONDON - - - EUR 195 454,80 - - - Frontiers in invasive species distribution modelling: incorporating human-associations and intraspecific niche structure to improve risk predictions. - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Biological invasions represent a major component of global change through their impacts on biodiversity, ecosystems and societies. Awareness of biological invasion impacts and the critical importance of evidence-based decision - making have led to a persistent effort to understand the factors driving invasion success so as to be able to predict invasion outcomes. To this end, a range of modelling tools has been developed. Among them, species distribution models (SDMs) - -phenomenological models that statistically relate observed species occurrences to environmental variables- play a critical role in invasion risk assessments. These models rely on ecological niche theory, which predicts that for recent events such as - biological invasions, conservatism of the climatic niche is expected. However, recent studies have demonstrated that this approach could be hampered by apparent niche shifts in invasive ranges. Mismatches between native and invasive distributions - derived from SDMs have been often interpreted as species adaptations in response to selection pressures in novel environments. However, methodological drawbacks of previous approaches fuel doubts about the biological meaning of these findings. In - this project, two unresolved challenges faced by SDMs when applied to the biological invasion process will be examined: how (1) species’ association with human-modified habitats in native ranges and (2) intraspecific niche variation shape the - distribution of invasive species at biogeographical scales and how these effects influence the reliability of predictions of invasion risk. To accomplish these goals, I will use an interdisciplinary approach combining global bird distribution data, - with molecular phylogenetic data and modern statistical and ecological analyses. The results of the project will contribute to improve prediction accuracy of biological invasions, and will also help better understand the invasion process. - - 2019-07-14, ongoing project - - - 2017-07-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - InvasiveSDM - - - H2020-MSCA-IF-2016 - - - 752149 - - - - - VYSOKE UCENI TECHNICKE V BRNE - VYSOKE UCENI TECHNICKE V BRNE - UNIVERSITAET STUTTGART - - - EUR 1 999 874 - - - THz Frequency Rapid Scan – Electron Spin Resonance spectroscopy for spin dynamics investigations of bulk and surface materials (THz-FRaScan-ESR) - - - EUR 1 999 874 - - - Czech Republic - Czech Republic - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Current high frequency electron spin resonance (HFESR) instruments suffer from the disadvantages of being limited to a single frequency and to tiny sample volumes. The study of spin dynamics at frequencies beyond a few hundred - gigahertz is currently prohibitively difficult. These limitations are now preventing progress in dynamic nuclear polarization (DNP) and preclude the implementation of zero-field quantum computing. In order to revolutionize sensitivity in nuclear - magnetic resonance (NMR) and magnetic resonance imaging (MRI) by means of DNP techniques allowing to watch in real time molecular interactions or even to monitor how sophisticated systems (ribosomes) work, the HFESR methods have to be substantially - improved. I will develop a novel and worldwide unique technique called broadband terahertz frequency rapid scan (FRaScan) ESR. I intend to implement this method into a working prototype, which will seamlessly span the entire frequency range from 100 - GHz to 1 THz, and allow spin dynamics investigation of large samples. This revolutionary new concept based on rapid frequency sweeps will remove all the restrictions and limitations of conventional HFESR methods used nowadays. It will enable for the - first time multi-frequency studies of quantum coherence also in zero magnetic field. It will lead to substantial increases in sensitivity and concurrent decrease of measurement time, thus allowing more efficient use of resources. Finally, the method - will allow identification of novel DNP signal enhancement agents, ultimately leading to a step change improvement of the MRI method. It will drastically shorten MRI scan times in hospitals, greatly enhancing patient comfort together with - significantly better and precise diagnoses. The method will lead to zero field quantum computers with computation power which will be never reached with conventional technology. In summary it will lead to impacts far beyond the scientific community. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Czech Republic - - - THz-FRaScan-ESR - - - ERC-2016-STG - - - 714850 - - - - - LUNDS UNIVERSITET - LUNDS UNIVERSITET - - - EUR 1 203 627 - - - Mathematical aspects of three-dimensional water waves with vorticity - - - EUR 1 203 627 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The goal of this project is to develop a mathematical theory for steady three-dimensional water waves with vorticity. The mathematical model consists of the incompressible Euler equations with a free surface, and vorticity is - important for modelling the interaction of surface waves with non-uniform currents. In the two-dimensional case, there has been a lot of progress on water waves with vorticity in the last decade. This progress has mainly been based on the stream - function formulation, in which the problem is reformulated as a nonlinear elliptic free boundary problem. An analogue of this formulation is not available in three dimensions, and the theory has therefore so far been restricted to irrotational flow. - In this project we seek to go beyond this restriction using two different approaches. In the first approach we will adapt methods which have been used to construct three-dimensional ideal flows with vorticity in domains with a fixed boundary to the - free boundary context (for example Beltrami flows). In the second approach we will develop methods which are new even in the case of a fixed boundary, by performing a detailed study of the structure of the equations close to a given shear flow using - ideas from infinite-dimensional bifurcation theory. This involves handling infinitely many resonances. - - 2021-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Sweden - - - 3DWATERWAVES - - - ERC-2015-STG - - - 678698 - - - - - FAKULTET ZA MASINSTVO I GRADJEVINARSTVO U KRALJEVO UNIVERZITETA U KRAGUJEVCU - ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA - STUDIO PEDRINI SRL - TOPOMATIKA TRODIMENZIONALNO SKENIRANJE, OPTICKI MJERNI SUSTAVI I RACUNALNA OBRADA DOO - PLAMINGO DOO, COMPANY FOR DOMESTIC AND FOREIGN TRADE, PRODUCTION AND SERVICES - - - EUR 468 000 - - - Advanced design rules for optimMAl Dynamic properties of Additive Manufacturing products - - - EUR 468 000 - - - Serbia - Italy - Italy - Croatia - Bosnia and Herzegovina - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Additive manufacturing (AM) belongs to key enabling technologies where Europe has the leading research role. The AM technologies put considerably fewer limits on shape of the manufactured objects than conventional - technologies, and offer unparalleled freedom to industrial and mechanical designers. Since the AM technologies are insensitive to production scale, they put in focus knowledge and creativity of designers instead of low prices of mass production, - paving the way to development of new business models. The AM technologies, therefore, represent a technology platform that may best serve Europe in its intent to develop knowledge-based economy, driven by innovation. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Serbia - - - A_MADAM - - - H2020-MSCA-RISE-2016 - - - 734455 - - - - - KATHOLIEKE UNIVERSITEIT LEUVEN - - - EUR 160 800 - - - HOUSING DUALIZATION: DIVIDED HOUSING CAREERS AND THE FINANCIALIZATION OF HOUSING MARKETS - - - EUR 160 800 - - - Belgium - - - Higher or Secondary Education Establishments - - Recent years have seen a transformation of housing careers. Significant homeownership declines among young adults is evident across Europe, with growing shares in rental or staying on in the parental home. These are not merely - symptoms of a temporary recession, but are outcomes of fundamental changes in labour and housing markets alongside shifting state roles. Even in so-called ‘homeowner societies,’ a future of mass homeownership appears unlikely. Rather, we see - increasingly divided sectors where insiders have seen sizable asset growth contrasted with significant shares shut out from the housing market. Globally, ‘financialization’ processes have been at forefront of housing market transformation. - Financialization describes real forces that have progressively changed the nature of housing, through its integration with global capital flows, neoliberal re/deregulation and increasing commodification: changes that may exacerbate the translation of - labour to housing divides. All this, in an era where labour inequalities have increased and housing assets have grown in importance in the face of welfare cutbacks. Given varied homeownership entry, diverging market outcomes, and intergenerational - transmission, housing is clearly central to structuring inequalities. Forces of financialization have only amplified the importance of housing towards socio-economic divides. The proposal develops a theoretical and empirical understanding of how - European housing is increasingly structured by insider-outsider dynamics - or housing dualization - within contexts of labour inequality and financialization. The quantitative approach is both multi-scalar and interdisciplinary. First addressing - macro-level housing divides across national settings, followed by multi-level analyses into individual outcomes structured by differing national and regional contexts. The research builds on distinct literatures across: labour market dualization, - comparative housing studies, and financialization. - - 2019-05-22, ongoing project - - - 2017-05-23 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Belgium - - - HOU-DUAL - - - H2020-MSCA-IF-2016 - - - 750866 - - - - - THE UNIVERSITY OF EDINBURGH - THE UNIVERSITY OF EDINBURGH - - - EUR 1 498 618 - - - Defining novel mechanisms critical for colorectal tumourigenesis - - - EUR 1 498 618 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Cancer genome sequencing has led to a paradigm shift in our understanding of oncogenesis. It has identified thousands of genetic alterations that segregate into two groups, a small number of frequently mutated genes and a much - larger number of infrequently mutated genes. The causative role of frequently mutated genes is often clear and are the focus of concerted therapeutic development efforts. The role of those infrequently mutated is often unclear and can be difficult to - separate from ‘mutational noise’. Determining the relevance of low frequency mutations is important for providing a full understanding of processes driving tumourigenesis and if functionally relevant may have broader implications on the applicability - of targeted therapies. - - 2022-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - COLGENES - - - ERC-2016-STG - - - 715782 - - - - - KAROLINSKA INSTITUTET - KAROLINSKA INSTITUTET - - - EUR 2 500 000 - - - Exploration and promotion of neurogenesis in the adult brain - - - EUR 2 500 000 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - It is now well established that new neurons are added to certain regions of the adult brain. There is today considerable interest in the development of regenerative therapies based on modulating endogenous neurogenesis, but it - is necessary to better understand these events to assess whether this is rational and realistic. - - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Sweden - - - Neurogenesis - - - ERC-2015-AdG - - - 695096 - - - - - OPTOELETTRONICA ITALIA SRL - DESTINA GENOMICA - UNIVERSITA DEGLI STUDI DI TRENTO - UNIVERSIDAD DE GRANADA - MEDIZINISCHE HOCHSCHULE HANNOVER - GENEXPLAIN GMBH - UNIVERSIDADE FEDERAL DE SANTA CATARINA. - - - EUR 445 500 - - - microRNA biomarkers in an innovative biophotonic sensor kit for high-specific diagnosis - - - EUR 490 500 - - - Italy - Spain - Italy - Spain - Germany - Germany - Brazil - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - Since 2001’s discovery of microRNAs (miRNAs) in humans, progress in genomics and transcriptomics has increased our comprehension of gene expression regulation. miRNAs are small, noncoding RNA molecules showing huge promise as - clinical biomarkers and diagnostic tools for illness and disease, as significant changes in their expression occur in response to pathological states. However, miRNA detection is still challenging nowadays, since costly, complex sample preparations - and RNA amplifications are not yet reliable enough for clinical decision making. In this context, three innovative EU companies, Optoi Microelectronics - with microelectronic knowhow and manufacturing skills - DestiNA Genomics - with ‘error free’ - chemical technology for microRNAs recognition – and GeneXplain – with bioinformatic capabilities - joined forces with four key academic research groups from the Universities of Trento (Italy), Granada (Spain), Hannover Medical School (Germany) and - Santa Catarina (Brazil). All the parties combined their knowledge with respect to miRNA biomarkers with a particular focus on lung cancer, to develop a novel and reliable miRNA detection system for this disease. To this end, research collaborations - will address the analysis of miRNAs specifically over-expressed in lung cancer, continuing experimental work already started in the past years, but with greater integration and focus. - - 2019-11-30, ongoing project - - - 2015-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Italy - - - miRNA-DisEASY - - - H2020-MSCA-RISE-2015 - - - 690866 - - - - - FUNDACIO INSTITUT CATALA DE NANOCIENCIA I NANOTECNOLOGIA - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - UNIVERSITE GRENOBLE ALPES - ASSOCIATION POUR LA RECHERCHE ET LE DEVELOPPEMENT DES METHODES ET PROCESSUS INDUSTRIELS - CENTRE HOSPITALIER UNIVERSITAIRE DE GRENOBLE - MULTI CHANNEL SYSTEMS MCS GMBH - UNIVERSITE DE GENEVE - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - WAVESTONE LUXEMBOURG S.A. - - - EUR 8 359 862,50 - - - High-density cortical implants for cognitive neuroscience and rehabilitation of speech using brain-computer interfaces. - - - EUR 8 648 827,89 - - - Spain - Spain - France - France - France - Germany - Switzerland - United Kingdom - Germany - Luxembourg - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The goal of BrainCom is to develop a new generation of neuroprosthetic devices for large-scale and high density recording and stimulation of the human cortex, suitable to explore and repair high-level cognitive functions. - Since one of the most invalidating neurospychological conditions is arguably the impossibility to communicate with others, BrainCom primarily focuses on the restoration of speech and communication in aphasic patients suffering from upper spinal cord, - brainstem or brain damage. To target broadly distributed neural systems as the language network, BrainCom proposes to use novel electronic technologies based on nanomaterials to design ultra-flexible cortical and intracortical implants adapted to - large-scale high-density recording and stimulation. The main challenge of the project is to achieve flexible contact of broad cortical areas for stimulation and neural activity decoding with unprecedented spatial and temporal resolution. Critically, - the development of such novel neuroprosthetic devices will permit significant advances to the basic understanding of the dynamics and neural information processing in cortical speech networks and the development of speech rehabilitation solutions - using innovative brain-computer interfaces. Beyond this application, BrainCom innovations will enable the study and repair of other high-level cognitive functions such as learning and memory as well as other clinical applications such as epilepsy - monitoring using closed-loop paradigms. BrainCom will be carried out by a consortium assembled to foster the emergence of a new community in Europe acting towards the development of neural speech prostheses. Thanks to its high interdisciplinarity - involving technology, engineering, biology, clinical sciences, and ethics, BrainCom will contribute advances to all levels of the value chain: from technology and engineering to basic and language neuroscience, and from preclinical research in - animals to clinical studies in humans. - - 2021-11-30, ongoing project - - - 2016-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.2."> - - - FETPROACT-01-2016 - FET Proactive: emerging themes and communities - - - RIA - Research and Innovation action - - - Spain - - - BrainCom - - - FETPROACT-2016 - - - 732032 - - - - - UNIVERSITY OF NEWCASTLE UPON TYNE - UNIVERSITY OF THE WEST OF ENGLAND, BRISTOL - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - LIQUIFER SYSTEMS GROUP GMBH - EXPLORA SRL - UNIVERSITA DEGLI STUDI DI TRENTO - - - EUR 3 216 555 - - - Living Architecture - - - EUR 3 216 555 - - - United Kingdom - United Kingdom - Spain - Austria - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - Living Architecture (LIAR) is a modular bioreactor-wall, which is based on the operational principles of microbial fuel cell technology and synthetic ‘consortia’ of microbes. LIAR is conceived as a next-generation - selectively-programmable bioreactor and integral component of human dwelling, capable of extracting valuable resources from waste water and air, generation of oxygen and production of proteins and fiber by manipulating consortia performance. Its - operational principles are grounded in distributed sensing, decentralised autonomous information processing, high-degree of fault-tolerance and distributed actuation and reconfiguration. Applications within urban systems are examined as a form of - customizable micro-agriculture for installation in domestic, public (schools, hospitals) and office environments. Such a system has far reaching impacts on the building performance (resilience, resource recycling) manufacturing and design with - ecosystems. - - 2019-03-31, ongoing project | - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-1-2014 - FET-Open research projects - - - RIA - Research and Innovation action - - - United Kingdom - - - LIAR - - - H2020-FETOPEN-2014-2015-RIA - - - 686585 - - - - - THE UNIVERSITY OF SHEFFIELD - UNIVERSITY COLLEGE LONDON - TECHNISCHE UNIVERSITEIT EINDHOVEN - POLITECNICO DI MILANO - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - THERENVA - LEEDS TEST OBJECTS LIMITED - LIFETEC GROUP BV - ANSYS FRANCE SAS - - - EUR 3 700 187,28 - - - VPH-Cardiovascular Simulation and Experimentation for Personalised Medical Devices - - - EUR 3 700 187,28 - - - United Kingdom - United Kingdom - Netherlands - Italy - France - France - United Kingdom - Netherlands - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - VPH-CaSE is focused on state-of-the-art developments in personalised cardiovascular support, underpinned by simulation and experimentation, building on the foundations of the Virtual Physiological Human (VPH) Initiative. The - Individual Research Projects of 14 ESRs provide knowledge exchange across three research clusters - - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - VPH-CaSE - - - H2020-MSCA-ITN-2014 - - - 642612 - - - - - VRIJE UNIVERSITEIT BRUSSEL - UNIVERSITY OF DUNDEE - - - EUR 160 800 - - - The role of national parliaments in the Arab transformation processes - - - EUR 160 800 - - - Belgium - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The research analyses the role of national parliaments in Egypt, Jordan, Morocco and Tunisia since 2011, and assesses their contributions to the political transformation processes. It diminishes an existing research gap since - parliaments have received almost no consideration in ‘Arab Spring’ research yet. Semi-structured interviews in all four countries with local parliamentarians, academics, NGO representatives, diplomats and similar decision-makers will produce primary - data that will be further discussed in workshops at academic institutions in Amman, Cairo, Rabat and Tunis as well as a conference at the University of Dundee. Peer-reviewed articles, open-access contributions and a monograph will disseminate - findings to the public. - - 2019-01-31, ongoing project - - - 2017-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Belgium - - - ARAB PARLIAMENTS - - - H2020-MSCA-IF-2015 - - - 706113 - - - - - POLITECNICO DI TORINO - FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG - UNIVERSITE DE RENNES I - UNIVERSITA DEGLI STUDI DI PADOVA - Ustav fyziky materialu, Akademie Ved Ceske republiky, v.v.i. - ELEMENT MATERIALS TECHNOLOGY HITCHIN LIMITED - COLOROBBIA CONSULTING SRL - Nanoforce Technology Limited - EUROPEAN THERMODYNAMICS LIMITED - - - EUR 3 882 899,52 - - - Advanced glasses, Composites And Ceramics for High growth Industries - - - EUR 3 882 899,52 - - - Italy - Germany - France - Italy - Czech Republic - United Kingdom - Italy - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The aim of CoACH (Advanced glasses, Composites And Ceramics for High growth Industries) is to offer a multidisciplinary training in the field of high-tech GLASSES, CERAMICS and COMPOSITES based on effective and proven - industry-academia cooperation. Our scientific goals are to develop advanced knowledge on glass and ceramic based materials and to develop innovative, cost-competitive, and environmentally acceptable materials and processing technologies. - - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Italy - - - CoACH - - - H2020-MSCA-ITN-2014 - - - 642557 - - - - - FOLKEHELSEINSTITUTTET - NASJONALT KUNNSKAPSSENTER FOR HELSETJENESTEN - - - EUR 208 400,40 - - - GUideline Implementation with DEcision Support systems - - - EUR 208 400,40 - - - Norway - Norway - - - Research Organisations - Research Organisations - - Healthcare based on the best available clinical evidence can lead to better quality of care. Evidence-based guidelines are potentially important instruments, but clinicians often do not adhere to them. - - 2017-07-14, closed project - - - 2015-07-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Norway - - - GUIDES - - - H2020-MSCA-IF-2014 - - - 654981 - - - - - POLITECNICO DI MILANO - - - EUR 244 269 - - - PHOto-induced Energy flow in Bio-inspired molecular circuits probed with Ultrafast two-dimensional Spectroscopy - - - EUR 244 269 - - - Italy - - - Higher or Secondary Education Establishments - - Solar energy is forecast to cover an important fraction of the world’s energy necessities over the next century. The energy captured from sunlight will be used to drive photovoltaic cells or to produce solar fuels, thus - Scientists must learn how to harvest, transfer and store it efficiently. In this framework, the PHOEBUS project aims at providing the design of innovative chemical structures (molecular circuits) that can control in sophisticated ways the flow of - excitation energy. - - 2018-09-30, ongoing project | - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Italy - - - PHOEBUS - - - H2020-MSCA-IF-2014 - - - 655059 - - - - - UNIVERSIDADE DO PORTO - LANCASTER UNIVERSITY - KARLSTADS UNIVERSITET - TECHNISCHE HOCHSCHULE KOLN - Värmlands läns landsting - UNIVERSITEIT MAASTRICHT - LINKOPINGS UNIVERSITET - EDP COMERCIAL-COMERCIALIZACAO DE ENERGIA SA - POLITECNICO DI MILANO - - - EUR 2 283 925,68 - - - Service Design for Innovation - - - EUR 2 283 926,12 - - - Portugal - United Kingdom - Sweden - Germany - Sweden - Netherlands - Sweden - Portugal - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - Service Design for Innovation (SDIN)-ETN aims to integrate service design and service innovation approaches that are now dispersed into an innovative research training framework; doing so leverages the creative power of - service design to foster innovation. Specific objectives are: creating a mass of researchers who can drive widespread application of service design to leapfrog innovation in European organisations; and developing interdisciplinary competences in the - key SDIN area and in key service sectors -ICT, public services and utilities. - - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Portugal - - - SDIN - - - H2020-MSCA-ITN-2014 - - - 642116 - - - - - PRIMA VERA S.P.A. - ZEPHYRO SPA - UNIVERSITAET BAYREUTH - AFEKA - THE ACADEMIC COLLEGE OF ENGINEERING IN TEL AVIV - POLITECNICO DI MILANO - ATHINA-EREVNITIKO KENTRO KAINOTOMIAS STIS TECHNOLOGIES TIS PLIROFOFORIAS, TON EPIKOLNONION KAI TIS GNOSIS - UNIVERSIDAD DE GRANADA - ENERTECH SOLUTION SRL - CTADVENTURE SP ZOO - MEAZON SA - AFEKA YISSUMIM LTD - - - EUR 1 206 000 - - - Support Tool for Energy Efficiency pRogrammes in medical centres - - - EUR 1 206 000 - - - Italy - Italy - Germany - Israel - Italy - Greece - Spain - Italy - Poland - Greece - Israel - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - To meet the greenhouse gas reduction targets set by the European Commission and to reduce the reliance on imported energy sources from not-EU countries, the energy efficiency sector vitally needs basic analytical and decision - support tools. This is especially true for large scale energy-consumer plants (for ex. foundries) but also for medical centres which typically (1) use large amounts of energy, (2) run a wide number of energy consuming machinery with different - electrical profiles, (3) serve a weak population that may be heavily affected by energy shortages, (4) have a continuous level of service with special periodicity and peak times, and (5) have to abide to all sorts of strict regulations (for ex. - special air quality requirements). - - - 2018-11-30, ongoing project | - - - 2014-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Italy - - - STEER - - - H2020-MSCA-RISE-2014 - - - 645694 - - - - - POLITECNICO DI MILANO - - - EUR 168 277,20 - - - Studying the bricks of microbial cities: characterization and structural properties of exopolysaccharides and their interaction with proteins and cations in anammox granular sludge - - - EUR 168 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - The anaerobic ammonium oxidation (anammox) is an innovative technology for the removal of nitrogen from wastewater (ww) saving 60% of aeration and 100% of organic carbon. Its potential application to municipal ww allow a - complete redesign of the present energy-consuming into an energy-yielding ww treatment plant. Due to the slow growth rate of anammox bacteria, their retention in the system, and therefore granule stability, is the main concern of this process. - Granular stability is closely related to the properties of their exopolysaccharides (PS) and their interactions with proteins and mono-divalent cations. In the proposed research integrated analytical methods (UV-visible, FT-IR, MALDI-TOF MS, NMR, - (pyrolysis)GC-MS, HPLC) will be used to investigate functional PS and their fine structures, unrevealing the mechanisms involved in anammox granular sludge formation and stability. Modern rheological (AOS, LLCT and Microrheology combined with CLSM), - light scattering (DLS, SLS) and microscopy techniques (AFM, FT-IR, CLSM) will be used to investigate their interactions with proteins and cations. PS will be isolated from lab- and full-scale reactors. The definition of standardized extraction - (loosely/tightly bound-EPS, LB/TB-EPS) and analytical methods will bridge the existing gap for efficient and meaningful comparison of the results from this and future research. The methods set up here, will largely contribute to increase the - scientific significance of PS studies in anammox granular sludge area as well as facilitate the entire biofilm research field. Studies on biofouling and biocorrosion will also benefit from the high-quality of the information and basic knowledge - acquired. This research will strengthen the EU leadership in anammox granular sludge technology also improving EU scientific excellence in PS research area and provides the researcher an advanced level of multidisciplinary training, opening concrete - perspectives for his career development. - - 2017-11-30, closed project - - - 2015-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - POLIS - - - H2020-MSCA-IF-2014 - - - 661429 - - - - - UNIVERSITY OF LEEDS - - - EUR 183 454,80 - - - Frequency Comb Spectroscopy of Temperature-dependent Reactions - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - This goal of this project is to obtain a deeper, molecular level understanding of chemical reactions important to atmospheric and planetary chemistry, specifically reactions involved in the oxidation of organic sulfur - molecules. A common theme to experimentally determining chemical reaction rates is to monitor the disappearance of a reactant, perhaps even under pseudo-first order conditions. An ideal experiment, however, would monitor the loss of each reactant and - the appearance of each product, under known temperature and pressure conditions, in order to gain a more complete picture of the reaction. This project is a significant step towards the ideal kinetic experiment. Here, mid-infrared cavity-enhanced - direct frequency comb spectroscopy (CE-DFCS), a technology used almost exclusively in the physics community, will be used as a tool in the chemistry community to spectroscopically identify reactants, transient species, and products based on their - vibrational absorption spectra. This is a rapid, sensitive, broadband, and high-resolution technique, which enables reaction rates to be derived based on the simultaneous measurement of both the reactant disappearance and product appearance. - Moreover, CE-DFCS will be coupled to a pulsed Laval supersonic expansion, an essentially wall-less reactor with well-characterized pressure and temperature conditions. Temperature dependent rate constants will be measured over a wide temperature - range, relevant to Earth’s atmosphere or even parts of the interstellar medium. This project has a strong interdisciplinary component, combining optical physics, fundamental physical chemistry, and atmospheric chemistry. This attribute arises from - the significant two-way transfer of knowledge between the researcher and the Atmospheric and Planetary Chemistry group at the University of Leeds. In addition, the fellow will receive training during the tenure of the fellowship to enable her to - become a successful independent scientist. - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - FCSpecTRe - - - H2020-MSCA-IF-2016 - - - 743642 - - - - - UNIVERSITA DEGLI STUDI DI TRENTO - - - EUR 168 277,20 - - - Characterizing the Occipital Oscillatory Activity in Blindness - - - EUR 168 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - The massive reorganization of the occipital regions as a consequence of lack of vision represents one of the most remarkable examples of the plastic potentialities of the human brain. Despite the large amount of neuroimaging - evidence proving the involvement of occipital areas of blind individuals in non‐visual input processing, the functional role of this sensory reorganized region is still matter of intense debate. In COcOAB, we will use an underexploited neuroimaging - technique in this field, magnetoencephalography (MEG), in order to study the oscillatory profile of ensembles of occipital neurons and their brain‐wide functional interaction patterns in blind individuals. This will allow us to gather unprecedented - information about the functional relevance of non‐visual activity in the occipital cortex of blind individuals. Moreover, COcOAB will assess the impact of age onset and duration of visual deprivation on the occipital oscillatory activity, thus - providing insights into the relationship between blindness and sensitive periods of maturation in the visual system. The groundbreaking potentials of COcOAB reside in the application of the MEG technique to the study of two experimental domains — - sensory illusions and stimulation at threshold — that has been so far neglected in the field of sensory deprivation. COcOAB represents a unique testing ground to address how specific regions support perception in a mechanistic fashion in visually - deprived individuals, thus challenging the current knowledge on the functionality of these reorganized regions via a highly innovative approach. - - 2018-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Italy - - - COcOAB - - - H2020-MSCA-IF-2015 - - - 701250 - - - - - UNIVERSITA DEGLI STUDI DI TRENTO - - - EUR 180 277,20 - - - Single-Cell Transcriptomics and Spliceosome analysis to uncover new mechanisms of neuronal vulnerability to Huntington’s Disease. - - - EUR 180 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - Huntington’s disease (HD) is neurodegenerative disease caused by a CAG repeat expansion mutation in the HTT gene. The pathological process, which ultimately leads to neuronal loss mainly in the caudate and putamen, is induced - - in a truly dominant manner - by a single copy of the mutant allele. Transcriptional deregulation has becoming a prevailing feature in HD and changes at single-gene level in RNA biogenesis and aberrant alternative splicing (AS) events have been - associated to neuronal vulnerability. Here, I propose to disentangle at genome-wide level the connections between mutant huntingtin expression and RNA processing, and its implications for neuronal vulnerability to death. Specifically, I propose to - study alterations in RNA transcription and AS in: Aim 1. Striatal, cortical and cerebellar areas of Hdh knock-in (KI) HD accurate mouse models through global RNAseq; Aim 2. In specific medium spiny neurons (MSN) of the Drd1 or Drd2 direct and - indirect pathways of Hdh KI striatum through laser capture dissection and single-cell RNAseq. - - - 2018-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Italy - - - TransSplicHD - - - H2020-MSCA-IF-2015 - - - 706567 - - - - - UNIVERSITA DEGLI STUDI DI TRENTO - - - EUR 180 277,20 - - - The role vision plays in shaping the representation of numbers. - - - EUR 180 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - In the literature on numerical cognition, vision was for a long time assumed to play an important role in the development of number representations. In line with this idea, I recently demonstrated that congenitally blind (CB) - present a qualitatively different representation of numbers by comparison to their sighted peers. In this project, I propose to further explore with fMRI techniques whether the CB qualitative different numerical representation is supported by - specific cerebral reorganisation of the brain. I also propose to examine whether the qualitative different numerical representations of CB could delay the acquisition of numerical concepts in childhood. I finally propose to explore the extent to - which this knowledge of the blind’s numerical representation could be extended to the elaboration of a multisensory mathematics teaching program. I advocate the idea that this research program is crucial because poor mathematical competencies are - common among adults and result in employment and day-to-day activities difficulties. Further research into multisensory access to numerical information could therefore lead to education benefits in teaching mathematics to young children but could - also promote interventions that target specific mathematical deficits. I am uniquely suited for working on this project due to a number of parallels between the skills the proposed project requires, and the skills I possess. This includes: 1) my - successful collaborations with Dr Collignon in the past; 2) good inter-personal skills; 3) my strong background in the research topic; 4) working with a variety of participant populations, and combining different methodologies. If funded, the present - project will allow me to continue to explore a large overarching question by applying my pre-existing knowledge to a broader range of experimental techniques and topics - a vital skill to become an independent researcher in Europe. - - 2018-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - NonVisNumCog - - - H2020-MSCA-IF-2015 - - - 700057 - - - - - UNIVERSITA DEGLI STUDI DI TRENTO - - - EUR 180 277,20 - - - River hydraulics, morphology, and vegetation: A case for improved knowledge and numerical model capabilities - - - EUR 180 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - The interdisciplinary knowledge and ability for river managers to effectively predict flood risks, restore rivers, and assess future alterations are currently restricted to the limited understanding of how river hydraulics, - morphology, and vegetation alter a river’s planform, effect sediment mobility, and control the surrounding habitats. To improve this knowledge and capabilities, this research seeks to i) use physical model flume experiments to quantify the hydraulic, - morphologic, and vegetation interactions of a braided channel as well as investigate the use of manipulated channel avulsion as an innovative method to increase a river’s floodplain conveyance, ii) to quantify the accuracy of a cutting-edge numerical - model’s simulations, and iii) to improve the numerical model’s functionality. Through increased knowledge, improved model capabilities, and potentially identifying a new technique to increase a degraded river’s floodplain dynamics, this research can - improve the efficacy of river managers around the world. In particular, Europe could utilize the contributions of this research to help meet the ecological-morphological aspects of the Water Framework Directives and Flood Directives and to restore - many of the heavily altered rivers of the European Alps. - - 2017-09-30, closed project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - River-HMV - - - H2020-MSCA-IF-2014 - - - 656917 - - - - - UNIVERSITA DEGLI STUDI DI TRENTO - - - EUR 180 277,20 - - - Assembly-based discovery of uncharacterized human microbiomemembers and their tracking across individuals and time - - - EUR 180 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - In this proposal we aim to expose and characterize members of the human-associated microbial dark matter and exploit the novel information to dramatically enhance the resolution of metagenomic profiling and develop accurate - predictive/diagnostic tools. - - 2018-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Italy - - - DiMeTrack - - - H2020-MSCA-IF-2015 - - - 707345 - - - - - UNIVERSITE PARIS-SUD - UNIVERSITE PARIS-SUD - POLITECNICO DI MILANO - - - EUR 1 498 125 - - - Chip-scale INtegrated Photonics for the mid-Infra REd - - - EUR 1 498 125 - - - France - France - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Mid-infrared (mid-IR) spectroscopy is a nearly universal way to identify chemical and biological substances, as most of the molecules have their vibrational and rotational resonances in the mid-IR wavelength range. - Commercially available mid-IR systems are based on bulky and expensive equipment, while lots of efforts are now devoted to the reduction of their size down to chip-scale dimensions. The demonstration of mid-IR photonic circuits on silicon chips will - benefit from reliable and high-volume fabrication to offer high performance, low cost, compact, low weight and power consumption photonic circuits, which is particularly interesting for mid-IR spectroscopic sensing systems that need to be portable - and low cost. - - - 2020-03-31, ongoing project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - INsPIRE - - - ERC-2014-STG - - - 639107 - - - - - ASSOCIATION POUR LA RECHERCHE ET LE DEVELOPPEMENT DES METHODES ET PROCESSUS INDUSTRIELS - ASSOCIATION POUR LA RECHERCHE ET LE DEVELOPPEMENT DES METHODES ET PROCESSUS INDUSTRIELS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE HOSPITALIER UNIVERSITAIRE SAINT ETIENNE - CHU - - - EUR 1 499 783 - - - Aneurysmal Arterial Mechanics: Into the Structure - - - EUR 1 499 783,02 - - - France - France - France - France - - - Research Organisations - Research Organisations - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - The rupture of an Aortic Aneurysm (AA), which is often lethal, is a mechanical phenomenon that occurs when the wall stress state exceeds the local strength of the tissue. Our current understanding of arterial rupture - mechanisms is poor, and the physics taking place at the microscopic scale in these collagenous structures remains an open area of research. Understanding, modelling, and quantifying the micro-mechanisms which drive the mechanical response of such - tissue and locally trigger rupture represents the most challenging and promising pathway towards predictive diagnosis and personalized care of AA. - - 2020-03-31, ongoing project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - AArteMIS - - - ERC-2014-STG - - - 638804 - - - - - POLITECNICO DI MILANO - POLITECNICO DI MILANO - - - EUR 1 499 020,97 - - - Control for Orbit Manoeuvring through Perturbations for Application to Space Systems - - - EUR 1 499 020,97 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Space benefits mankind through the services it provides to Earth. Future space activities progress thanks to space transfer and are safeguarded by space situation awareness. Natural orbit perturbations are responsible for the - trajectory divergence from the nominal two-body problem, increasing the requirements for orbit control; whereas, in space situation awareness, they influence the orbit evolution of space debris that could cause hazard to operational spacecraft and - near Earth objects that may intersect the Earth. However, this project proposes to leverage the dynamics of natural orbit perturbations to significantly reduce current extreme high mission cost and create new opportunities for space exploration and - exploitation. - - 2021-07-31, ongoing project - - - 2016-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Italy - - - COMPASS - - - ERC-2015-STG - - - 679086 - - - - - POLITECNICO DI MILANO - POLITECNICO DI MILANO - - - EUR 2 484 648 - - - Structured Reactors with INTensified ENergy Transfer for Breakthrough Catalytic Technologies - - - EUR 2 484 648,75 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Critically important heterogeneous catalytic reactions for energy conversion and chemicals production have been run for several decades in fixed bed reactors randomly packed with catalyst pellets, whose operation is - intrinsically limited by slow heat removal/supply. There is urgent need for a new generation of process equipment and chemical reactors to address the current quest for process intensification. I propose that a game-changing alternative is provided - by structured reactors wherein the catalyst is washcoated onto or packed into structured substrates, like honeycomb monoliths, open-cell foams or other cellular materials, fabricated with highly conductive metallic (Al, Cu) materials. The goal of - this project is to fully elucidate fundamental and engineering properties of such novel conductive structured catalysts, investigate new concepts for their design, manufacturing, catalytic activation and operation (e.g. 3D printing, packed foams, - energy supply by solar irradiation), and demonstrate their potential for a quantum leap in the intensification of three crucial catalytic processes for the production of energy vectors: i) distributed H2 generation via efficient small-size reformers; - ii) conversion of syngas to clean synthetic fuels in compact (e.g. skid-mounted) reactors; iii) production of solar H2. To this purpose I will combine advanced CFD modelling with lab-scale experimentation in order to identify the optimal - structure-performance relation of existing and novel substrates, use such new knowledge to design optimized prototypes, apply unconventional additive manufacturing technologies for their production, and construct a semi-industrial tubular pilot - reactor to test them at a representative scale. The project results will enable novel reactor designs based on tuning geometry, materials and configurations of the conductive internals to match the activity - selectivity demands of specific process - applications, while impacting also other research areas. - - 2021-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Italy - - - INTENT - - - ERC-2015-AdG - - - 694910 - - - - - POLITECNICO DI MILANO - POLITECNICO DI MILANO - ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI - - - EUR 1 903 330 - - - Mechanobiology of nuclear import of transcription factors modeled within a bioengineered stem cell niche. - - - EUR 1 903 330 - - - Italy - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - Many therapeutic applications of stem cells require accurate control of their differentiation. To this purpose there is a major ongoing effort in the development of advanced culture substrates to be used as “synthetic niches” - for the cells, mimicking the native ones. The goal of this project is to use a synthetic niche cell culture model to test my revolutionary hypothesis that in stem cell differentiation, nuclear import of gene-regulating transcription factors is - controlled by the stretch of the nuclear pore complexes. If verified, this idea could lead to a breakthrough in biomimetic approaches to engineering stem cell differentiation. - - 2020-04-30, ongoing project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Italy - - - NICHOID - - - ERC-2014-CoG - - - 646990 - - - - - UNIVERSITA DEGLI STUDI DI TRENTO - UNIVERSITA DEGLI STUDI DI TRENTO - - - EUR 1 472 502 - - - Cortical Representation of Abstract Semantic Knowledge - - - EUR 1 472 502 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The study of semantic memory considers a broad range of knowledge extending from basic elemental concepts that allow us to recognise and understand objects like ‘an apple’, to elaborated semantic information such as knowing - when it is appropriate to use a Wilcoxon Rank-Sum test. Such elaborated semantic knowledge is fundamental to our daily lives yet our understanding of the neural substrates is minimal. The objective of CRASK is to advance rapidly beyond the - state-of-the-art to address this issue. CRASK will begin by building a fundamental understanding of regional contributions, hierarchical organisation and regional coordination to form a predictive systems model of semantic representation in the - brain. This will be accomplished through convergent evidence from an innovative combination of fine cognitive manipulations, multimodal imaging techniques (fMRI, MEG), and advanced analytical approaches (multivariate analysis of response patterns, - representational similarity analysis, functional connectivity). Progress will proceed in stages. First the systems-level network underlying our knowledge of other people will be determined. Once this is accomplished CRASK will investigate general - semantic knowledge in terms of the relative contribution of canonical, feature-selective and category-selective semantic representations and their respective roles in automatic and effortful semantic access. The systems-level model of semantic - representation will be used to predict and test how the brain manifests elaborated semantic knowledge. The resulting understanding of the neural substrates of elaborated semantic knowledge will open up new areas of research. In the final stage of - CRASK we chart this territory in terms of human factors: understanding the role of the representational semantic system in transient failures in access, neural factors that lead to optimal encoding and retrieval and the effects of ageing on the - system. - - 2020-04-30, ongoing project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Italy - - - CRASK - - - ERC-2014-STG - - - 640594 - - - - - POLITECNICO DI MILANO - POLITECNICO DI MILANO - - - EUR 1 496 250 - - - Structure-dependent microkinetic modelling of heterogeneous catalytic processes - - - EUR 1 496 250 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Despite the fact that the catalyst structure has been an important factor in catalysis science since the discovery of structure sensitive reactions in single crystal studies, its effect on reactivity is neglected in - state-of-the-art microkinetic modelling. In reality, the catalyst is dynamic by changing its structure, shape and size in response to the different conditions in the reactor. Thus, the inclusion of such effects within the framework of microkinetic - modelling, albeit extremely complex, is of outmost importance in the quest of engineering the chemical transformation at the molecular level. This proposal aims to approach this grand challenge by developing a hierarchical multiscale methodology for - the structure-dependent microkinetic modelling of catalytic processes in applied catalysis. In particular this challenging objective will be achieved by acting on two main fronts: - - - 2021-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Italy - - - SHAPE - - - ERC-2015-STG - - - 677423 - - - - - UNIVERSITAT AUTONOMA DE BARCELONA - UNIVERSITAT AUTONOMA DE BARCELONA - - - EUR 1 453 868 - - - Green Locally Unwanted Land Uses - - - EUR 1 453 868 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project examines the role played by the restoration and creation of environmental amenities in the redistribution of urban quality of life. Since no large-scale study has been conducted to measure if greener cities are - less racially and socially equitable, I will analyze whether greening projects tend to increase environmental inequalities in 40 cities in the US and Europe and under which conditions such projects can address equity concerns. First, the study will - a) develop a new method (an index) to quantify the racial and social impact of greening projects and to compare cities’ performance with each other; b) provide a spatial and quantitative analysis of neighborhood demographic, real estate, and - environmental data; and c) apply the index methodology on a unique ranking of cities. Second, my research will analyze the response of private investors to the greening projects and identify the impact of new development projects proposed, approved, - and implemented during or upon the completion of greening projects on the neighborhood socio-demographic characteristics. I will assess the extent to which development projects seem to encourage and/or accelerate gentrification, as such projects have - been shown to be signs of residents’ exclusion. Additionally, this study will qualitatively analyze cases of community mobilization developed in response to new environmental amenities, through fieldwork in 16 critical neighborhoods (one neighborhood - case per city) among the 40 cities. Last, this study will use qualitative methods to analyze the policies and measures that municipalities develop to address exclusion in “greening” neighborhoods. This groundbreaking longitudinal, systematic, - in-depth, and large-scale project in the field of environmental justice will lead to a paradigm shift by hypothesizing that the social and racial inequities present in sustainability projects make green amenities Locally Unwanted Land Uses (LULUs) - for poor residents and people of color. - - 2021-05-31, ongoing project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Spain - - - GREENLULUS - - - ERC-2015-STG - - - 678034 - - - - - POLITECNICO DI MILANO - POLITECNICO DI MILANO - - - EUR 2 500 000 - - - Data-Driven Genomic Computing - - - EUR 2 500 000 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Next-generation sequencing technology has dramatically reduced the cost and time of reading the DNA. Huge investments are targeted to sequencing the DNA of large populations, and repositories of well-curated sequence data are - being collected. Answers to fundamental biomedical problems are hidden in these data, e.g. how cancer arises, how driving mutations occur, how much cancer is dependent on environment. But genomic computing has not comparatively evolved. - Bioinformatics has been driven by specific needs and distracted from a foundational approach; hundreds of methods solve individual problems, but miss the broad perspective. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Italy - - - GeCo - - - ERC-2015-AdG - - - 693174 - - - - - POLITECNICO DI MILANO - POLITECNICO DI MILANO - UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II. - - - EUR 1 994 932,50 - - - LIVING IN A FRINGE ENVIRONMENT - Investigating occupation and exploitation of desert frontier areas in the Late Roman Empire - - - EUR 1 994 932,50 - - - Italy - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The scope of LIFE is to offer a complete set of archaeological and environmental data to be used to investigate Late Roman settlements along frontier desert areas and to reconstruct the underlying strategy to control the - empire’s desert edges. The case study is the chain of Late Roman fortified settlements that punctuate the Kharga Oasis (Egypt’s Western Desert), that in the Fourth Century represented a portion of the southern boundary of the empire. All these sites, - located in a remote and harsh environment, share the same architectural features and are endowed with similar agricultural installations, thus suggesting the existence of a highly motivated large-scale strategy of occupation of the region. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Italy - - - L.I.F.E. - - - ERC-2015-CoG - - - 681673 - - - - - TECHNISCHE UNIVERSITAET MUENCHEN - - - EUR 214 828,20 - - - Non-Leptonic Three-Body B Decays: Theory and Phenomenology - - - EUR 214 828,20 - - - Germany - - - Higher or Secondary Education Establishments - - Tests of the Standard Model (SM) of Particle Physics and the search for New Physics (NP) is a central issue in the European program in High-Energy Physics. Weak decays of heavy hadrons have a unique potential for the - extraction of SM parameters, the study of CP violation, and the search for NP. Among these, decays of B mesons into three final hadrons are of huge phenomenological interest. They have been studied experimentally at B factories and at the LHC, and - will be a cornerstone in the physics program at Belle-II. However, the theoretical basis for such processes has yet not been developed. Through this project, we will establish the theoretical grounds for the description of non-leptonic three-body B - decays, from basic principles to phenomenological applications. - - 2019-12-31, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Germany - - - NIOBE - - - H2020-MSCA-IF-2015 - - - 700525 - - - - - POLITECNICO DI MILANO - POLITECNICO DI MILANO - - - EUR 1 887 500 - - - Exploring the New Science and engineering unveiled by Ultraintense ultrashort Radiation interaction with mattEr - - - EUR 1 887 500 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - With the ENSURE project I aim at attaining ground-breaking results in the field of superintense laser-driven ion acceleration, proposing a multidisciplinary research program in which theoretical, numerical and experimental - research will be coherently developed in a team integrating in an unprecedented way advanced expertise from materials engineering and nanotechnology, laser-plasma physics, computational science. The aim will be to bring this topic from the realm of - fundamental basic science into a subject having realistic engineering applications. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Italy - - - ENSURE - - - ERC-2014-CoG - - - 647554 - - - - - UNIVERSITY OF LEEDS - TOSHIBA RESEARCH EUROPE LIMITED - UNIVERSIDAD DE VIGO - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSITA DEGLI STUDI DI PADOVA - HEINRICH-HEINE-UNIVERSITAET DUESSELDORF - UNIVERSITE DE GENEVE - ID QUANTIQUE SA - INSTITUT MINES-TELECOM - UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6 - - - EUR 3 924 884,52 - - - Quantum Communications for ALL - - - EUR 3 924 884,52 - - - United Kingdom - United Kingdom - Spain - France - Italy - Germany - Switzerland - Switzerland - France - France - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Quantum Communications for ALL (QCALL) endeavors to take the next necessary steps to bring the developing quantum technologies closer to the doorsteps of end users. Quantum communications (QC) is well-known for its offering - ultra-secure cryptographic key-exchange schemes—resilient to any future technological advancement. QCALL will empower a nucleus of researchers in this area to provide secure communications in our continent and, in the long run, to our connections - worldwide. With the large scale violations of privacy in the EU exchange of information, this is a crucial moment to pursue this objective. By covering a range of projects, with short, mid, and long-term visions, and using a balanced and multifaceted - training programme, QCALL trains a cadre of highly qualified interdisciplinary workforce capable of shaping the R&D section of the field, hence accelerating its widespread adoption. This will ensure that EU will remain at the frontier of research - on secure communications and advanced QC systems and devices. In QCALL, we explore the challenges of integrating quantum and classical communication networks; this will be essential in providing cost-efficient services. We experimentally examine and - theoretically study new protocols by which network users can exchange secure keys with each other. We investigate disruptive technologies that enable wireless access to such quantum networks, and develop new devices and protocols that enable - multi-party QC. Our meticulously planned training programme includes components from shared taught courses through to scientific schools and complementary-skill workshops, supplemented by secondment opportunities and innovative outreach and - dissemination activities. This will create a structured model for doctoral training in EU that will last beyond the life of the project, so will the industry-academic collaborations that are essential to the development of the disruptive technologies - that will make QC available to ALL. - - 2020-11-30, ongoing project - - - 2016-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - QCALL - - - H2020-MSCA-ITN-2015 - - - 675662 - - - - - CONSIGLIO NAZIONALE DELLE RICERCHE - UNIVERSIDAD DE MALAGA - TECHNISCHE UNIVERSITAT DARMSTADT - UNIVERSITA DEGLI STUDI DI TRENTO - UNIVERSITY OF KENT - BRITISH TELECOMMUNICATIONS PUBLIC LIMITED COMPANY - ATOS SPAIN SA - - - EUR 3 882 227,76 - - - European Network for Cyber-security - - - EUR 3 882 227,76 - - - Italy - Spain - Germany - Italy - United Kingdom - United Kingdom - Spain - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The European Network for Cybersecurity (NECS) was formed in response to the increased need of highly qualified experts able to cope with all the aspects of the European cybersecurity strategy that is currently under implementation. - - 2019-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Italy - - - NeCS - - - H2020-MSCA-ITN-2015 - - - 675320 - - - - - DANMARKS TEKNISKE UNIVERSITET - KATHOLIEKE UNIVERSITEIT LEUVEN - UNIVERSITAET BREMEN - INSTITUTTET FOR PRODUKTUDVIKLING - POLITECNICO DI MILANO - UNIVERSITY OF STRATHCLYDE - UNIVERSITY OF BRADFORD - TECHNISCHE UNIVERSITAET CHEMNITZ - THE UNIVERSITY OF NOTTINGHAM - - - EUR 3 446 156,52 - - - European Training Network on “Process Fingerprint for Zero-defect Net-shape MICROMANufacturing” - - - EUR 3 446 156,52 - - - Denmark - Belgium - Germany - Denmark - Italy - United Kingdom - United Kingdom - Germany - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The continuous trend towards miniaturization and multi-functionality embedded in products and processes calls for an ever increasing innovation, research and development within the European manufacturing sector. A necessary - condition for the European productive sector to be at the global forefront of technology, ensuring job creation and sustainable growth, is to have access to innovative, entrepreneurial, highly skilled research engineers in the fields of micro - manufacturing and micro product/process development. The MICROMAN ITN will provide world excellent research training to 13 ESR in the field of micro manufacturing proposing: (1) innovative technological solutions for high quality and high throughput - micro production (micro manufacturing process fingerprint, zero-defect net-shape micro manufacturing) for the micro manufacturing industry; (2) cutting edge inter-disciplinary training in different domains (µ-polymer moulding, µ-metal forming, - µ-extrusion, µ-tooling technologies, µ-product metrology, µ-manufacturing process metrology); (3) validation of different micro manufacturing processes by integration into process chains for the production of micro component for the bio-medical, - health-care, machine tool, pharmaceutical, quality control sectors. The training strategy is based on the 50-30-20 principle, in which each single ESR will develop a core technical competence, a complementary technical competence, and a general - technical competence in all domains addressed by the project with a research effort proportional to the 50%-30%-20% of the total effort. An all-round, comprehensive yet specialized, training in micro manufacturing will be ensured. Specific training - on project engineering research management and entrepreneurship completes the training and provides the ESR the required skills to effectively contribute to the competitiveness of the European micro manufacturing industry, and in turn to job creation - and well-being of the European society. - - 2019-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Denmark - - - MICROMAN - - - H2020-MSCA-ITN-2015 - - - 674801 - - - - - POLITECNICO DI MILANO - POLITECNICO DI MILANO - - - EUR 1 822 500 - - - Very fast Imaging by Broadband coherent RAman - - - EUR 1 822 500 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The VIBRA project aims at developing an innovative microscope for real-time non-invasive imaging of cells and tissues, which promises to have a revolutionary impact on several fields of biology and medicine. Chemically - specific vibrational signatures of molecules enable their direct structural characterization. Reliable and quantitative endogenous bio-markers can be established, e.g., to follow cell differentiation and to identify crucial properties of tissues - (malignant vs benign phenotype of a tumour). In this way neoplasms can be located and their borders with normal tissue traced for surgery. - - - 2020-05-31, ongoing project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Italy - - - VIBRA - - - ERC-2014-CoG - - - 648615 - - - - - POLITECNICO DI MILANO - Eidgenössische Technische Hochschule Zürich - UNIVERSIDADE DO PORTO - INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE - CINECA CONSORZIO INTERUNIVERSITARIO - VYSOKA SKOLA BANSKA - TECHNICKA UNIVERZITA OSTRAVA - DOMPE FARMACEUTICI SPA - SYGIC AS - - - EUR 3 115 251 - - - AutoTuning and Adaptivity appRoach for Energy efficient eXascale HPC systems - - - EUR 3 115 251,25 - - - Italy - Switzerland - Portugal - France - Italy - Czech Republic - Italy - Slovakia - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Energy-efficient heterogeneous supercomputing architectures need to be coupled with a radically new software stack capable of exploiting the benefits offered by the heterogeneity at all the different levels (supercomputer, - job, node) to meet the scalability and energy efficiency required by Exascale supercomputers. - - 2018-08-31, ongoing project | - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.2."> - - - FETHPC-1-2014 - HPC Core Technologies, Programming Environments and Algorithms for Extreme Parallelism and Extreme Data Applications - - - RIA - Research and Innovation action - - - Italy - - - ANTAREX - - - H2020-FETHPC-2014 - - - 671623 - - - - - UNIVERSITAET GRAZ - SVEUCILISTE U ZAGREBU FAKULTET ELEKTROTEHNIKE I RACUNARSTVA - SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO SANT'ANNA - UNIVERSITE LIBRE DE BRUXELLES - ASSOCIATION POUR LA RECHERCHE ET LE DEVELOPPEMENT DES METHODES ET PROCESSUS INDUSTRIELS - CORILA - CONSORZIO PER IL COORDINAMENTO DELLE RICERCHE INERENTI AL SISTEMA LAGUNARE DI VENEZIA - CYBERTRONICA UG (HAFTUNGSBESCHRANKT) GMBH - - - EUR 3 987 650 - - - SUBMARINE CULTURES PERFORM LONG-TERM ROBOTIC EXPLORATION OF UNCONVENTIONAL ENVIRONMENTAL NICHES - - - EUR 3 987 650,75 - - - Austria - Croatia - Italy - Belgium - France - Italy - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - subCULTron aims for achieving long-term autonomy in a learning, self-regulating, self-sustaining underwater society/culture of robots in a high-impact application area: Venice, Italy. Our heterogeneous system consists of 3 - different agent types: On the sea-ground, artificial mussels are the collective long-term memory of the system, allowing information to stay beyond the runtime of other agents, thus allowing to continue learning from previously learned states. These - mussels monitor the natural habitat, including biological agents like algae, bacterial incrustation and fish. On the water surface, artificial lilypads interface with the human society, delivering energy and information influx from ship traffic or - satellite data. Between those two layers, artificial fish move/monitor/explore the environment and exchange info with the mussels and lilypads. Artificial mussels are a novel class of underwater agents. We aim to push forward the edge of knowledge - with novel sensors (electric sense/electro-communication), novel bio-inspired algorithms (underwater hives) and novel energy harvesting in underwater scenarios. We will improve the world’s record for swarm-size in autonomous collective underwater - robotics by almost one order of magnitude. Our application field is a human- and animal-co-inhabited real-world environment of high impact: Venice canals & lagoon. These habitats are highly dynamic and structured, expected to be reflected by a - spatial self-structuring of our mussel population. These sub-populations locally perform memetic/ cultural learning algorithms on their specific local data. Thus our cultural evolution algorithms will promote sub-culture development, similar to the - human society that does the same above the water level in parallel. Overall, we aim for an artificial society underneath the water-surface to the service of a human society above the water. - - 2019-03-31, ongoing project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.2."> - - - FETPROACT-2-2014 - Knowing, doing, being: cognition beyond problem solving - - - RIA - Research and Innovation action - - - Austria - - - subCULTron - - - H2020-FETPROACT-2014 - - - 640967 - - - - - POLITECNICO DI MILANO - POLITECNICO DI MILANO - - - EUR 149 625 - - - Mid Infrared SpectrometerS by an Innovative Optical iNterferometer - - - EUR 149 625 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The MISSION projects aims at bringing to the market a revolutionary concept of mid-infrared (MIR) interferometer, for a new generation of compact, low-cost, rugged spectrometers. Many applications of chemistry, materials - science and life sciences require analysis and identification of substances based on their vibrational absorption spectra in the MIR. Time domain vibrational spectroscopy techniques such as FTIR and 2DIR are based on the use of an optical Michelson - interferometer, producing two identical phase-shifted replicas of the input beam. Phase determination is technically very challenging and requires tracking with an auxiliary laser beam and in some cases the use of active stabilization approaches, - with feedback control on the interferometer arms, greatly increasing device complexity. We have recently introduced a new optical interferometer, called TWINS, which exploits material birefringence to impose highly controllable delays. TWINS has the - advantages of being inherently phase stable, compact, rugged, highly reproducible and potentially low cost. The TWINS concept, for which a patent has been filed, was successfully demonstrated in the visible and the MIR spectral ranges. It is the goal - of the MISSION project to unleash the innovation potential of TWINS, by developing, technically validating and bringing to the market a TWINS-based MIR interferometer, paving the way to a new generation of compact and low-cost analytical instruments - for a wide range of applications. We have identified a suitable material with broad MIR transparency and huge birefringence: calomel. The MISSION project aims at: i) building a TWINS device based on calomel; ii) demonstrating its application to MIR - spectroscopy; and iii) turning it into a commercial product, to be sold either as stand-alone device or as part of a spectroscopic instrument. We expect that TWINS will significantly reduce the cost of MIR interferometers, thus widely broadening - their application portfolio. - - 2016-11-30, closed project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2014 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Italy - - - MISSION - - - ERC-2014-PoC - - - 665635 - - - - - LABORATORIO EUROPEO DI SPETTROSCOPIE NON LINEARI - FUNDACIO INSTITUT DE CIENCIES FOTONIQUES - UNIWERSYTET JAGIELLONSKI - UNIVERSITA DEGLI STUDI DI TRENTO - Eidgenössische Technische Hochschule Zürich - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 2 386 875 - - - Quantum simulations of insulators and conductors - - - EUR 2 774 375 - - - Italy - Spain - Poland - Italy - Switzerland - France - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - It is now accepted that the conducting or insulating nature of matter is based on various separate ingredients (e.g. disorder, interactions, band filling, dimensionality, topology, etc.). However, their complex interplay is - still beyond our understanding because experiments are very difficult and numerical calculations are often inefficient, even for supercomputers. In QUIC we want to achieve a breakthrough in the understanding of the fundamental mechanisms governing - insulators and conductors by using quantum simulators, i.e. quantum computers of special purpose, based on fully controllable ultracold gases. In an experiment-theory enterprise, we will engineer several different kinds of such synthetic quantum - matter, where we can isolate and study quantitatively the quantum phenomena and phases. We will not only study the physics of real systems, such as disordered and strongly-correlated superconductors and superfluids, but we will also create systems - that do not exist so far in nature, such as topological phases in graphene-like lattices. QUIC combines for the first time advanced manipulation techniques of ultracold atomic gases, innovative theoretical ideas of condensed-matter physics and - quantum-information methods. The immediate goals of our project are to understand quantitatively the subtle interplay of quantum phenomena in insulators and conductors, explore new promising directions for the engineering of transport in real - materials, and lay the foundations for the design of the quantum materials of tomorrow. - - 2019-02-28, ongoing project - - - 2015-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.2."> - - - FETPROACT-3-2014 - Quantum simulation - - - RIA - Research and Innovation action - - - Italy - - - QUIC - - - H2020-FETPROACT-2014 - - - 641122 - - - - - POLITECNICO DI MILANO - POLITECNICO DI MILANO - - - EUR 1 998 113,12 - - - REsistive-Switch CompUting bEyond CMOS - - - EUR 1 998 113,12 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Digital computers rely today on CMOS (complementary metal-oxide-semiconductor) technology, which improves its performance every generation thanks to the Moore’s law of downscaling. As CMOS transistor size approaches few nm, - alternative logic switches with better scaling capability must be identified to prolong Moore’s law beyond CMOS. Among the emerging switching concepts, resistive switching (RS) devices can change their resistance by electrically-induced redox - reactions. RS provides the basis for the resistive memory (ReRAM) technology which is currently investigated as future computer memory and storage technology. The objective of this project is to design, develop and demonstrate a novel computing - paradigm based on RS devices. The project will pursue this objective at 3 levels of increasing complexity, namely the device fabrication, the design of new logic gates and the demonstration of computing circuits. RS logic will be finally compared to - CMOS and other approaches to identify the strength and the potential applications of RS logic in the computing scenario. - - 2020-07-31, ongoing project - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Italy - - - RESCUE - - - ERC-2014-CoG - - - 648635 - - - - - ASSOCIATION POUR LA RECHERCHE ET LE DEVELOPPEMENT DES METHODES ET PROCESSUS INDUSTRIELS - ASSOCIATION POUR LA RECHERCHE ET LE DEVELOPPEMENT DES METHODES ET PROCESSUS INDUSTRIELS - - - EUR 149 673 - - - Exploitation of Organic Electrochemical Transistors for Biological Ionsensing – Proof Of Concept - - - EUR 149 673 - - - France - France - - - Research Organisations - Research Organisations - - The IONOSENSE-POC project proposes a novel solution to enable label-free, electronic monitoring of live cells in vitro, using innovative organic bioelectronic technology. The device, the organic electrochemical transistor - (OECT), integrated with live cells forming a tissue, has been shown to accurately assess the integrity of the cells, providing dynamic, highly sensitive measurements after exposure to toxins/pathogens. Validation against traditional, optical methods, - or commercially available electronic monitoring equipment demonstrated the OECT to have equal or improved sensitivity and temporal resolution. As an added bonus, the OECT is fabricated using conducting polymers, which are not only amenable to low - cost processing techniques, but are also optically transparent, yielding devices compatible with high resolution imaging techniques, of critical importance to life scientists. In the POC project, we propose to take this extremely promising - technological breakthrough developed in an academic environment, and transition it to a prototype suitable for future commercialization. In parallel, the appropriate steps will be taken necessary to ascertain the market niche(s), initially identified - as being in the areas of Biomems targeted for diagnostics/drug discovery. Finally, an adapted exploitation strategy will be developed to best suit the technology developed during the IONOSENSE project. The team assembled to execute the project is - extremely committed to the commercialization venture, in particular due to significant feedback from industrial partners (potential endusers) from such diverse biomedical applications as the cosmetics industry, neurotoxicology, electrophysiology - instrumentation developers, drug development companies etc. The success of this POC project will have broad ranging, highly positive impacts for society in the EU and further, due to reduction of experimentation on animals, improved healthcare - outcomes, and economic development to name a few. - - 2016-09-30, closed project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2014 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - France - - - IONOSENSE-POC - - - ERC-2014-PoC - - - 665725 - - - - - POLITECNICO DI MILANO - - - EUR 244 269 - - - Patterning Spin-Wave reconfIgurable Nanodevices for loGics and computing. - - - EUR 244 269 - - - Italy - - - Higher or Secondary Education Establishments - - Spin-waves, i.e. propagating perturbations in the spin arrangement of magnetic materials, are envisioned to revolutionize the way information is carried and processed due to their multiplexing capability and absence of Joule - losses. By bringing together the complementary expertise of “CUNY Advanced Science Research Center” (USA) and “Politecnico di Milano (PoliMi)” (Italy), the ‘SWING’ project addresses two major issues of current nanoscale magnonics: the efficient - guidance of spin-waves in nanostructured materials and the study of spin-waves at the nanoscale. - - 2019-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Italy - - - SWING - - - H2020-MSCA-IF-2015 - - - 705326 - - - - - UNIVERSITA DEGLI STUDI DI TRENTO - - - EUR 180 277,20 - - - Alpine lakes benthic viral community structure and diversity: a metagenomic and ecological approach - - - EUR 180 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - Viruses are a key and yet neglected component of freshwater ecosystems. By impacting bacterial communities they influence evolutionary dynamics, mineralisation processes, energy transfer across trophic levels and greenhouse - gas emission. Nonetheless, they are among the least understood organisms. - - 2018-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - Italy - - - metaVir-Alp - - - H2020-MSCA-IF-2015 - - - 704603 - - - - - UNIVERSITA DEGLI STUDI DI TRENTO - UNIVERSITA DEGLI STUDI DI TRENTO - - - EUR 1 996 428 - - - Synthetic Lethal Phenotype Identification through Cancer Evolution Analysis - - - EUR 1 996 428 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Prostate cancer (PCA) is a genetically heterogeneous disease. Advances in targeted hormonal therapy (second generation anti-androgens) have led to more effective management of castration-resistant prostate cancer (CRPC). - Despite these highly potent drugs, disease recurs with new genomic and epigenetic alterations. In this ERC proposal, I will leverage my expertise in cancer genomics and a new computational methodology to unravel the landscape of lethal PCA, with a - focus on determining the Achilles’ heel of these aggressive tumours. In Aim 1, I will take advantage of DNA sequencing data from over 1000 patient-derived tumour samples and use highly innovative mathematical algorithms to create a detailed evolution - chart for each tumour and identify driver events leading to CRPC. After nominating candidate drivers, we propose testing 10 using in vitro gain- and loss-of-function validations experiments (i.e., CRISPR/Cas9, shRNA, and Tet-On assays) in PCA cell - lines using migration, invasion, and cell cycle as readouts. In Aim 2, I will focus on genomic events that occur in recalcitrant CRPC, positing that genetic alterations occurring prior or secondary to treatment harbour clues into resistance. In vitro - validations will be performed on the top 10 biomarkers. In Aim 3, I will nominate synthetic lethality combinations by mining CRPC genomic data taken from Stand Up 2 Cancer CRPC clinical trials. I will prioritize mutually exclusive genomic alterations - in genes for which approved drugs exist. The top 5-10 candidates will be validated in a prostate lineage-specific manner. In summary, this ERC proposal will leverage my many years of expertise in PCA genomics and emerging public and private CRPC - datasets to uncover driver mutations that will enhance our understanding of recalcitrant CRPC. Successful completion of this study should lead to novel treatment approaches for CRPC and to a computational model that may transform our approach to - evaluating other cancers. - - 2020-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Italy - - - SPICE - - - ERC-2014-CoG - - - 648670 - - - - - UNIVERSITA DEGLI STUDI DI TRENTO - - - EUR 168 277,20 - - - A New View on Real Actions: Neural Mechanisms of Visuo-Motor Transformations - - - EUR 168 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - The goal of this project proposal is to investigate the neural mechanisms of motor control in relation to primary visual function in healthy adults. In particular, I will examine the role of primary visual cortex (V1) in - action planning and execution by using a combination of neuroimaging, neurostimulation and behavioural techniques. - - 2018-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Italy - - - BraIn Action - - - H2020-MSCA-IF-2015 - - - 703597 - - - - - UNIVERSITA DEGLI STUDI DI TRENTO - POLSKO JAPONSKA WYZSZA SZKOLA TECHNIK KOMPUTEROWYCH PJWSTK - Ente Ospedaliero Cantonale - - - EUR 931 500 - - - Social Participation for improving emotional, mental, and physical wellbeing in independently living older adults - - - EUR 931 500 - - - Italy - Poland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - The combination of longer life expectancy, evolving socio-economical norms and conditions, and new technologies are dramatically changing life after retirement, and not always for the better. In more and more countries, - pensioners find themselves with many years in front of them, some of them likely characterized by reduced physical and cognitive abilities. For older adults, this span of time out of the workforce was traditionally devoted to the role (and source of - great joy) of caring for grandchildren. However, this role is fading out because of increased mobility of children, which often live far away for work, love, or other reasons, leading to an increase of loneliness and social isolation. This project - aims at rethinking long life and understanding the socio-economical context that can make this period of life more exiting and attractive. - - 2019-01-31, ongoing project - - - 2016-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Italy - - - DREAM - - - H2020-MSCA-RISE-2015 - - - 690962 - - - - - INSTITUT MINES-TELECOM - ECOLE NATIONALE SUPERIEURE DES MINES DE SAINT-ETIENNE - - - EUR 173 076 - - - Smart electroactive 3D models of osteoregeneration - - - EUR 173 076 - - - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In the European Union alone, the annual number of bone fractures is projected to reach 4.5 million in 2025. Despite the advances in implant technology, grafts prepared using bone extracted from the patient to fill the bone - defect are the only material reported so far to retain any significant efficacy in sustaining new bone formation. However, the aging worldwide population and increased life expectancy call for a different answer to the growing need for effective - implants for bone fracture healing. - - - 2018-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - SMART-BONE - - - H2020-MSCA-IF-2015 - - - 704175 - - - - - UNIVERSITA DEGLI STUDI DI TRENTO - UNIVERSITA DEGLI STUDI DI TRENTO - - - EUR 149 943,75 - - - SILKENE: Bionic silk with graphene or other nanomaterials spun by silkworms - - - EUR 149 943,75 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - "The project aims at designing, developing, scaling-up and optimizing a pre-industrial process towards the mass production of “silkene”, a bionic silk fiber reinforced with graphene, or other nanomaterials such as nanotubes, - directly spun by silkworms. The idea is simply based on nanomaterial ingestion and subsequent “silkene” spinning by silkworms. Silkene is expected to be significantly stronger and tougher that its natural counterpart. Since silk produced by silkworms - has already impacted our society, the impact of SILKENE project could also be significant. The process under consideration should in this project be technically verified, optimized and taken to a pre-commercial stage, for applications in industrial - sectors such as smart or high-performance technical fibers, textiles, and related reinforced composites. The concept has been already preliminarily (see http://arxiv.org/abs/1504.06751) demonstrated at the laboratory scale with spiders, within our - ERC Starting Grant "Bio-inspired Hierarchical Super Nanomaterials" (BIHSNAM)." - - 2017-08-31, closed project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2015 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Italy - - - SILKENE - - - ERC-2015-PoC - - - 693670 - - - - - UNIVERSITAT ZU LUBECK - POLITECNICO DI MILANO - OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN - - - EUR 823 500 - - - Approximation Methods for Molecular Modelling and Diagnosis Tools - - - EUR 823 500 - - - Germany - Italy - Austria - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - This proposal brings together research teams from the EU (Germany, Italy, and Austria) and the Ukraine (Kyiv, Donezk) in the area of applied mathematics with emphasis on medical and life science applications. - - - 2019-07-31, ongoing project - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Germany - - - AMMODIT - - - H2020-MSCA-RISE-2014 - - - 645672 - - - - - UNINOVA-INSTITUTO DE DESENVOLVIMENTO DE NOVAS TECNOLOGIAS-ASSOCIACAO - NOVA ID FCT - ASSOCIACAO PARA A INOVACAO E DESENVOLVIMENTO DA FCT - ECOLE NATIONALE SUPERIEURE DES MINES D'ALES - INSTITUT MINES-TELECOM - LAPPEENRANNAN TEKNILLINEN YLIOPISTO - DONETSK INSTITUTE FOR PHYSICS AND ENGINEERING NAMED AFTER O.O. GALKIN OF THE NATIONAL ACADEMY OF SCIENCESS OF UKRAINE - SOLENE-R - Blueorizon - Projectos de Engenharia, Unipessoal, Lda - - - EUR 873 000 - - - Advanced Humidity to Electricity Converter - - - EUR 873 000 - - - Portugal - Portugal - France - France - Finland - Ukraine - France - Portugal - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The HUNTER project will develop revolutionary power devices that convert humidity into electrical charge (hygroelectricity), thereby contributing to the European technology and creativity through joint R&D and R&I - multisectorial and international cooperation activities supported by knowledge sharing. The devices will harvest electricity from atmospheric humidity and supply a current, such as solar cells capture sunlight and generate electrical power. The - successful realization of the project is assured by implementing a coordinated network of knowledge sharing in materials science, physics and chemistry; by solidifying the state-of-the-art understanding in nanoelectronics and by applying bottom-up - nanoengineering approaches via an international and inter-sector collaboration of highly qualified researchers from Portugal, France, Finland, Ukraine, Belarus and USA. Both technological (nanoelectronic device fabrication) and fundamental (charge - transport mechanisms) issues will be assessed by this multidisciplinary consortium. - - 2019-11-30, ongoing project - - - 2015-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Portugal - - - HUNTER - - - H2020-MSCA-RISE-2015 - - - 691010 - - - - - LUCIDEON LIMITED - THE UNIVERSITY OF WESTMINSTER LBG - POLITECNICO DI TORINO - FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG - VORNIA LIMITED - UNIVERSITY OF SOUTHAMPTON - UNIVERSITAETSKLINIKUM KNAPPSCHAFTSKRANKENHAUS BOCHUM GMBH - - - EUR 3 918 054,96 - - - Drug-Free Antibacterial Hybrid Biopolymers for Medical Applications - - - EUR 3 918 054,96 - - - United Kingdom - United Kingdom - Italy - Germany - Ireland - United Kingdom - Germany - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - There is a general consensus that biomedical polymers of natural and synthetic origin should and will play a very important role in the development of new therapeutic strategies to treat diseases. Due to resistance of bacteria - to drugs, infection has become one of the toughest problems in the medical world as there are hardly any effective antibiotics left in the fight against many pathogens. This project aims to develop new therapies through a new combination of - technology (a) development of new hybrid polymers with antibacterial functionality,(b) introduction of inhibitors that can permanently deactivate bacteriological proteases and (c) new formulations of bioactive ceramics and glasses that have specific - charge potential to prevent bacterial growth. The challenge is to develop new medical polymers that have an intrinsic antibacterial functionality to achieve clinical effectiveness in the field. To develop the challenge to practical medical solutions, - a new generation of industrial professionals is needed. They should have a solid multidisciplinary background complemented by the required academic and industrial experiences. The objective of this network is to train young PhD researchers to fill - this demand in the strategic area of drug-free antibacterial hybrid biomedical polymers. This EID programme will achieve this by a joint training programme of world class academic and industrial institutes who will provide hands-on training in state - of the art research projects related to key fundamental issues that determine the future new therapies of antibacterial biomaterials. The goal is to develop professionals that will play a pivotal role in pushing forward this challenging and - knowledge-intense field for the coming decades to benefit the European economy, bring state-of-the-art technology to industry with advanced products for hospitals and personal health care and contribute to the development of therapeutic strategies to - improve the quality of life. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-EID - Marie Skłodowska-Curie Innovative Training Networks (ITN-EID) - - - MSCA-ITN-EID - European Industrial Doctorates - - - United Kingdom - - - HyMedPoly - - - H2020-MSCA-ITN-2014 - - - 643050 - - - - - POLITECNICO DI MILANO - ECOLE CENTRALE DES ARTS ET MANUFACTURES - UNIVERSITE LIBRE DE BRUXELLES - TECHNISCHE UNIVERSITAT DARMSTADT - - - EUR 3 832 293,60 - - - Combustion for Low Emission Applications of Natural Gas - - - EUR 3 832 293,60 - - - Italy - France - Belgium - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Natural Gas (NG) will be one of the key parameters of the EU energy policy for the next decades. EU gas imports are expected to reach over 80% of total consumption by 2030. Thus, the EU is investing heavily in natural gas equipment. - - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-EJD - Marie Skłodowska-Curie Innovative Training Networks (ITN-EJD) - - - MSCA-ITN-EJD - European Joint Doctorates - - - Italy - - - CLEAN-Gas - - - H2020-MSCA-ITN-2014 - - - 643134 - - - - - NOVA ID FCT - ASSOCIACAO PARA A INOVACAO E DESENVOLVIMENTO DA FCT - LABORATORIO NACIONAL DE ENGENHARIA CIVIL - ECOLE NATIONALE SUPERIEURE DES MINES D'ALES - INSTITUT MINES-TELECOM - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - INSTITUTO DE SOLDADURA E QUALIDADE - AR DIAGNOSTIC TECNOLOGIAS DE MONITORIZACAO E CONTROLO DO AR LDA - TECHNOLOGIES EXPERTISES RECHERCHES ANALYTIQUES EN ENVIRONNEMENT - AMBISALUD CALIDAD AMBIENTAL SL - ORRION CHEMICALS METALCHEM - DONETSK INSTITUTE FOR PHYSICS AND ENGINEERING NAMED AFTER O.O. GALKIN OF THE NATIONAL ACADEMY OF SCIENCESS OF UKRAINE - MATERIALS RESEARCH CENTER - NANOTECHCENTER LLC - UNIVERSITE PARIS-SUD - BELARUSIAN STATE UNIVERSITY - - - EUR 1 386 000 - - - NANOMATERIALS-BASED INNOVATIVE ENGINEERING SOLUTION TO ENSURE SUSTAINABLE SAFEGUARD TO INDOOR AIR - - - EUR 1 386 000 - - - Portugal - Portugal - France - France - France - Portugal - Portugal - France - Spain - France - Ukraine - Ukraine - Ukraine - France - Belarus - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The overall project idea is on contribution to European culture and creativity through developing technological readiness of the breakthrough engineering solution for indoor air safeguard via inter-sectoral European and - international cooperation, knowledge sharing, broad skills development and mobility of researchers and innovation staff. - - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Portugal - - - NANOGUARD2AR - - - H2020-MSCA-RISE-2015 - - - 690968 - - - - - UNIVERSITE D'ANGERS - - - EUR 185 076 - - - Gender and transnational Humanitarian Commitment for Children (Europe - 1980-2007) - - - EUR 185 076 - - - France - - - Higher or Secondary Education Establishments - - The main objective of this project is to examine the extent to which “gender”, as category of analysis, can be a useful tool in explaining the nature and the impact of humanitarian aid of western organizations towards children - in Europe, between 1980 and 2007, using as case study the relation France (initiator)-Romania (beneficiary). The main objectives are: to identify all the stakeholders involved in the humanitarian aid for children, the targeted problems, if the large - framework of intervention to see if formally it addressed these gender particularities; to describe the grassroots activity and the human resources of the humanitarian organisations involved in aiding the children, with a special focus on the - motivation(s) that stood behind both the personal and institutional involvement and of there any differences between women and men; a survey on the local impact of each of the major intervention axes, insisting on sensitive issues, such as the - accusations of paedophilia and the scandal surrounding international adoptions. - - 2019-09-03, ongoing project - - - 2017-09-04 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - GenHumChild - - - H2020-MSCA-IF-2016 - - - 748770 - - - - - UNIVERSITA DEGLI STUDI DI TORINO - POLITECNICO DI TORINO - UNIVERSITA DEGLI STUDI DEL PIEMONTE ORIENTALE AMEDEO AVOGADRO - UNIVERSITA DEGLI STUDI DI SCIENZE GASTRONOMICHE - CENTROSCIENZA ONLUS ASSOCIAZIONE - CREATIVA IMPRESA DI COMUNICAZIONE SRL - - - EUR 184 250 - - - Tenth Researchers' night Anniversary for Citizenship in the Knowledge Society - - - EUR 279 250 - - - Italy - Italy - Italy - Italy - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The Researchers’ Night has been for the eight past editions a regular appointment for researchers and for the different publics of science in Piedmont. - - 2015-11-30, closed project - - - 2014-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.5."> - - - MSCA-NIGHT-2014 - European Researchers' Night (NIGHT) - - - CSA - Coordination and support action - - - Italy - - - TRACKS - - - H2020-MSCA-NIGHT-2014 - - - 633275 - - - - - UNIVERSITY OF LEEDS - - - EUR 195 454,80 - - - Antiferromagnetic straintronics: towards an non-volatile all-voltage controlled memory device - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The holy grail of magnetic storage research is the discovery of novel all-voltage controlled magnetic metamaterials that enable to develop a universal memory device that simultaneously meet high-power-efficiency and ultra-high - storage capacity. Antiferromagnetic (AFM) materials could represent the future of spintronic applications as a result of the numerous interesting features they combine, e.g. they are robust against perturbation due to magnetic fields, produce no - stray fields, display ultrafast dynamics and are capable of generating large magneto-transport effects. However, the truly distinctive feature posed by AFM materials when compared to ferromagnetic ones is its modulated magnetic order, which is - marginally exploited in spintronics applications. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - PiezoSpin - - - H2020-MSCA-IF-2016 - - - 748691 - - - - - UNIVERSITA DEGLI STUDI DI TRENTO - META GROUP SRL - - - EUR 99 750 - - - WhiteRabbit: easily revealing and managing personal information. - - - EUR 99 750 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - WhiteRabbit aims to bring to the market an innovative software platform. The platform will allow to extract value from personal data, while keeping its subjects in the loop and also complying with upcoming regulations. - - 2018-07-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-04-2016-2017 - FET Innovation Launchpad - - - CSA - Coordination and support action - - - Italy - - - WhiteRabbit - - - H2020-FETOPEN-4-2016-2017 - - - 754436 - - - - - UNIVERSITA DEGLI STUDI DI TRENTO - UNIVERSITA DEGLI STUDI DI TRENTO - - - EUR 1 499 482 - - - Culture-free strain-level population genomics to identify disappearing human-associated microbes in the westernized world - - - EUR 1 499 482 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Investigating symbiotic gut microbes with large-scale comparative genomics would allow gaining crucial insights into the “epidemiology”, genetic diversity, and population structure of hundreds of scarcely characterized - microorganisms. However, cultivation-based approaches are ineffective at targeting the large fraction of the gut microbial diversity that is hard be grown in vitro. They are also expensive and time consuming, as they need sampling specific bacteria - from geographically separated subjects. On the other hand, cultivation-free metagenomic data is now available for thousands of stool samples collected worldwide, but they are not currently exploited for strain-level microbial population genomics - because of the lack of suitable computational methods. In Aim1, we leverage our expertise in computational biology to bridge the gap between the fields of metagenomics and population genomics by developing novel and highly innovative methodologies to - extract strain-level genomic and genetic profiles from metagenomic samples with the resolution needed by comparative genomics. Such paradigmatic shift will put us in the position of reusing in Aim2 the thousands of available metagenomes and unravel - for the first time the population structure of hundreds of uncultivable gut microbes. Among the novel tasks enabled, we will focus in Aim3 on identifying those microbial strains that are currently disappearing in westernized populations as a - consequence of urbanization, industrialization, high-fat diets. We will complement the available data with gut metagenomes from novel targeted cohorts of both westernized and non-westernized populations. Our project defines the foundation for - cultivation-free strain-level population genomics, provides comparative genomics results with unprecedented resolution for hundreds of under-investigated microbes, and compiles a catalogue of strains undergoing or at risk of primary, secondary, or - ecological extinction in westernized populations. - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Italy - - - MetaPG - - - ERC-2016-STG - - - 716575 - - - - - UNIVERSITA DEGLI STUDI DI TRENTO - - - EUR 180 277,20 - - - RNA-mediated intercellular miscommunication: role of extracellular vesicle cargos in Amyotrophic Lateral Sclerosis - - - EUR 180 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - Amyotrophic Lateral Sclerosis (ALS) is a rare neurodegenerative disorder that primarily targets upper and lower motor neurons. The progression of the disease is mediated by altered intercellular communication in the spinal - cord between neurons and glial cells. Intercellular communication, mainly happening through extracellular vesicles (EVs) is responsible for the horizontal transfer of proteins and RNAs to recipient cells. Recently, I proved that EVs released from ALS - mutant astrocytes selectively induced toxicity in wild type motor neuron, thus reinforcing the notion that astrocytes exert toxicity in ALS disease propagation and suggesting EVs as mediators of toxicity. Although, multiple factors can play a role in - motor neuron degeneration, recent evidences point toward a fundamental role for RNA and RNA-binding protein dys-homeostasis as crucial players in ALS pathogenesis. Therefore, the overarching goal of ExItALS is to characterize the astrocyte-EVs RNA - cargos, -through RNA deep-sequencing (Aim1). This approach will be complemented by the use of high-resolution flow cytometry (secondment) to separate EV populations and determine which one(s) is(are) responsible for motor neuron toxicity (Aim2). The - present research proposal is a synthesis of my interests in neurodegenerative diseases and my expertise in biochemistry and neurobiology. At the Host Institution I will greatly benefit from the scientific exchange with several PIs interested in RNA - biology, particularly with my supervisor, whose skills in RNA-binding protein biology and bioinformatics analyses will perfectly integrate and consolidate my molecular and biochemical expertise. The MSCA-RI-IF will be instrumental to develop this - initial hypothesis into deeper biological understanding of ALS and represent a crucial support to my scientific integration as a competitive, woman investigator in the transition from a researcher position to an independent academic career. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Italy - - - ExItALS - - - H2020-MSCA-IF-2016 - - - 752470 - - - - - KING'S COLLEGE LONDON - - - EUR 183 454,80 - - - A Nano-photoelectric Exosome Biosensor for Point-of-care Diagnosis of Early-stage Cancer - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Tumour-derived circulating exosomes are an ideal, easily accessible reservoir of cancer biomarkers to assess disease processes. Quantitatively pinpointing exosome tumour markers, a clinical field of an unmet need is appealing, - yet challenging. The main objectives of the proposal are to develop an integrated dual-signalling exosome biosensor (ExoSensor) for rapid and specific detection of GPC1+ exosomes and fabricate a 3D-printed portable prototype for POCT diagnosis of - pancreatic cancer, offering an universal technology for clinical cancer diagnosis through quantitatively monitoring the protein marker of cancer-derived exosomes, in a simple way. The novelty resides in creatively achieving accurate, sensitive, and - simultaneous detection of exosomes by integrating two synergetic methods (optical and electrochemical) on one single nanosensing platform, avoiding false positive/negative results to the utmost and ensuring the reliability of tests. This European - Fellowship at Kings College London will provide the researcher with advanced technical training in molecular biology, exosome, cancer cell and animal handling, analytical chemistry and microscopy and imaging techniques, as well as academic mentoring - in research management. A secondment to Cardiff University will seek and confirm the best possible biomarker(s). Another secondment to the industrial partner AstraZeneca Ltd will offer access to various exosomes research (diagnostics, toxicology and - therapeutics) and evaluate the feasibility of commercial transfer if possible. Guy’s, St Thomas, and King’s College Hospital (part of King’s Health Partners) will provide valuable clinical samples for final validation stage. Other collaborators will - advise on 3D-printing, pancreatic cancer and biomarkers. These interdisplinary contributions are essential and well-related to the proposal research, fostering high-quality cooperation from biology, chemistry, engineering, nanotechnology and clinical - areas the other way round. - - 2019-10-10, ongoing project - - - 2017-10-11 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ExoSensor - - - H2020-MSCA-IF-2016 - - - 749087 - - - - - UNIVERSITA DEGLI STUDI DI TRENTO - - - EUR 180 277,20 - - - A novel in vivo platform to study and target undruggable Ewing onco-chimera. - - - EUR 180 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - Development of efficient therapeutic strategies in the past years has drastically reduced the lethality of several common types of pediatric and juvenile form of cancer such as leukemia, lymphoma and brain tumors. Such a - tremendous success, however, does not include sarcomas treatment, whose mortality rate remains the same as twenty years ago. - - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - Italy - - - EwiSarc - - - H2020-MSCA-IF-2016 - - - 749795 - - - - - UNIVERSITA DEGLI STUDI DI TRENTO - - - EUR 180 277,20 - - - Quantifying ecological effects of small hydropower in Alpine stream ecosystems - - - EUR 180 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - In Europe, hydropower is the largest renewable energy resource accounting for 16% of total production, most of which is concentrated in the Alpine region. However, this renewable energy comes at great environmental costs and - development of large dams is now considered untenable in many Countries. While studies addressing the ecological implications of hydropower have mostly focused on large facilities, investigations on small hydropower (SHP) are scarcer. Yet, - development of SHP is booming globally and in the Alps rising concerns about cumulative effects on riverine systems. - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - SHYDRO-ALP - - - H2020-MSCA-IF-2016 - - - 748969 - - - - - INSTITUT MINES-TELECOM - INSTITUT MINES-TELECOM - - - EUR 1 495 287,52 - - - Context- and Task-Oriented Communication - - - EUR 1 495 287,52 - - - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Emergence of a large number of distributed decision and control systems (e.g., in health care, transportation, and energy management), combined with increasing demands of traditional communications (e.g., due to multiview - videos), create an imminent need for highly improved communication systems. We advocate that—combined with improvements in battery, antenna, and chip technologies—context- and/or task-oriented communication techniques will bring the desired - breakthrough. Specifically, context- oriented techniques will greatly improve performance, because future networks have complex infrastructures (with cache-memories, cloud-RANs, etc.) allowing the terminals to collect side-informations about other - terminals’ data or signals, and because many distributed decision systems rely on numerous devices with correlated measurements. Task-oriented techniques promise even larger gains, especially in distributed decision systems where decisions take value - on a small range, and thus the traditional approach of communicating sequences of observed signals results in a huge overhead. - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - CTO Com - - - ERC-2016-STG - - - 715111 - - - - - POLITECNICO DI MILANO - TECHNISCHE UNIVERSITAET BERLIN - FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA - STICHTING VU - - - EUR 742 500 - - - Localized Surface Plasmon Resonance in doped semiconductor nanocrystals - - - EUR 1 107 000 - - - Italy - Germany - Italy - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Chiara Andreoli - Tel.: +3901071781854 - Fax: +39 010 7170817 - Higher or Secondary Education Establishments - - Doped semiconductor nanocrystals (dSNCs) are an exciting emerging material. Carrier densities in the range of 1020-1021cm-3 lead to localized surface plasmon resonances (LSPRs) in the near infrared (NIR). Prominent examples - are copper chalcogenides, where doping occurs via vacancy formation, and metal oxides (MOs) that show plasmonic response due to impurity doping. Excitingly, both materials display post synthetic carrier density and LSPR tunability over a broad - spectral range. Combined with layered two dimensional materials exciting manipulation options appear where the plasmon-exciton coupling or ‘hot’ carrier extraction enables local photo luminescence manipulation or tracking of local currents in a - graphene based nano device. This active control over the LSPR allows active switching of the strength of coupling, useful also for the study of exciton-plasmon, plasmon-plasmon coupling, or plasmon induced ‘hot’ carrier extraction in - nano-heterostructures. Ultralow doping allows the study of quantum plasmonics. Ultrafast photodoping, optical switching, active light manipulation or tunable NIR photon detection are additional exciting applications. While fundamental questions - regarding the structure-properties relationship remain open to date the library of materials with such properties is enormous and not yet exhausted. - - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Italy - - - SONAR - - - H2020-MSCA-RISE-2016 - - - 734690 - - - - - INSTITUT MINES-TELECOM - - - EUR 173 076 - - - Bioconductive Iongels for Cutaneous Electrophysiology - - - EUR 173 076 - - - France - - - Higher or Secondary Education Establishments - - Bioelectronics is limited by the materials that transducer signals across the interface between biology and electronics. For example, in cutaneous recording, the interface between the electrode and skin is the key parameter to - get a good recording. For these applications, there is a great deal of interest in developing soft conducting coatings that decrease the impedance between the electrode and the skin. Hence, the interface between the skin and the electrode is improved - allowing an easier flow of the ionic and electronic current. Although hydrogel based electrolytes are in use, the continuous evaporation of water does not allow the long-term cutaneous recording. The current proposal is aiming at exploring innovative - materials such as iongels that can enhance the ionic conductivity and decrease the impedance with the human skin without suffering evaporation during the recording due to the negligible vapour pressure of ionic liquids. These cutaneous electrodes - will be used to monitor the electrical activity of specific organs for a better understanding of the physiology and the pathology of different organs. - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - BIKE - - - H2020-MSCA-IF-2016 - - - 742865 - - - - - GREGOR-MENDEL-INSTITUT FÜR MOLEKULARE PFLANZENBIOLOGIE GMBH - GREGOR-MENDEL-INSTITUT FÜR MOLEKULARE PFLANZENBIOLOGIE GMBH - - - EUR 1 500 000 - - - Function and Evolution of Attack and Response Strategies during Allelopathy in Plants - - - EUR 1 500 000 - - - Austria - Austria - - - Research Organisations - Research Organisations - - In natural and agricultural habitats, plants grow in organismal communities and therefore have to compete for limited resources. Competition between different crop plants and between crops and weeds leads to losses of - potential agricultural product and requires heavy use of fertilizer and herbicides, with negative effects for the environment and human health. Plants have evolved various strategies to outcompete their neighbours and to secure their access to - resources; one of them is the release of toxic chemical compounds into the soil that interfere with the growth of neighbouring plants. Many of today’s major crops, such as wheat, rye and maize, produce phytotoxins. Conversely, crop species also - suffer from chemical attack by other plants growing in their vicinity. Although many of the chemical compounds applied in this biochemical warfare have been identified, we know little about how they act in the target plant; neither do we understand - how some plant species are able to tolerate this chemical attack. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Austria - - - FEAR-SAP - - - ERC-2016-STG - - - 716823 - - - - - RIJKSUNIVERSITEIT GRONINGEN - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - TECHNISCHE UNIVERSITAET CHEMNITZ - BAYERISCHE JULIUS-MAXIMILIANS UNIVERSITAT WURZBURG - UNIVERSITE DE MONS - TECHNISCHE UNIVERSITAET DRESDEN - HELIATEK GMBH - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - UNIVERSITE D'ANGERS - MERCK CHEMICALS LTD - FUNDACIO EURECAT - - - EUR 3 826 023,84 - - - Spins for Efficient Photovoltaic Devices based on Organic Molecules - - - EUR 3 826 023,84 - - - Netherlands - United Kingdom - Germany - Germany - Belgium - Germany - Germany - Spain - France - United Kingdom - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - - Organic solar cells (OSCs) have the potential to become an environmental friendly, inexpensive, large area and flexible photovoltaics technology. Their main advantages are low process temperatures, the potential for very low - cost due to abundant materials and scalable processing, and the possibility of producing flexible devices on plastic substrates. To improve their commercialization capacity, to compete with established power generation and to complement other - renewable energy technologies, the performance of state-of-the-art OSCs needs to be further improved. - - 2020-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Netherlands - - - SEPOMO - - - H2020-MSCA-ITN-2016 - - - 722651 - - - - - UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA - UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA - - - EUR 2 000 000 - - - e-Sequence: a sequential approach to engineer heteroatom doped graphene nanoribbons for electronic applications - - - EUR 2 000 000 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Graphene nanoribbons (NR) are quasi-1D nanostructures with discrete band gaps, ballistic conduction, and one-atom thickness. Such properties make them ideal candidates to develop low-dimensional semiconductors, which are - essential components in nanoelectronics. Atomically-precise control over the structure of NR (width, length, edge, doping) is crucial to fully exploit their potential. However, current approaches for the synthesis of NR suffer from several drawbacks - that do not allow attaining such level of precision, therefore alternative methods need to be sought. - - 2022-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Spain - - - e-Sequence - - - ERC-2016-COG - - - 722951 - - - - - CITY UNIVERSITY OF LONDON - CITY UNIVERSITY OF LONDON - - - EUR 1 499 672 - - - Revealing the neurocognitive mechanisms underlying the visual perception of social interactions - - - EUR 1 499 672 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - “Social perception” has emerged as an umbrella term to describe research addressing the visual perception of others. To date, this discipline has focused on the perception of individuals; for example, researchers have examined - the visual processing of faces and facial expressions, body shapes and postures, actions and kinematics. The resulting body of research suggests that social stimuli are detected by specialised mechanisms, recruit dedicated perceptual models, and are - processed by particular neural substrates. However, while social perception research has made considerable progress elucidating the visual perception of individuals, virtually nothing is known about the visual perception of social interactions; how - we detect, encode, and interpret visual displays of social interactions viewed from third-person perspectives. Given the adaptive value of accurate interaction interpretation, this paucity of knowledge represents a remarkable gap in our understanding - of social perception. POINTS will develop a battery of original behavioural and neuroimaging paradigms to reveal the neurocognitive mechanisms that mediate this essential form of social perception. The overarching objective of POINTS will be achieved - by addressing five research questions: 1) Do observers exhibit evidence of interaction detection mechanisms? 2) How do we process fleeting visual displays of social interactions? 3) How do we represent dynamic interaction change? 4) Do specialised - neural substrates mediate interaction perception? 5) Do some observers exhibit impaired interaction perception? The POINTS project represents a significant step-change in social perception research. Understanding the mechanisms of interaction - perception will provide new insights into the organisation of the human visual system, and will inform attempts to remediate socio-cognitive and perceptual deficits in neurodevelopmental populations, including those with Autism Spectrum Disorder. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - POINTS - - - ERC-2016-STG - - - 715824 - - - - - SERVICIO DE SALUD DE CASTILLA LA MANCHA - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - AXON CABLE - UNIVERSITA DEGLI STUDI DI TRENTO - KUNGLIGA TEKNISKA HOEGSKOLAN - UNIVERSITE D'AIX MARSEILLE - UNIVERSITAT DES SAARLANDES - - - EUR 5 094 120 - - - Biofunctionalised Electroconducting Microfibres for the Treatment of Spinal Cord Injury - - - EUR 5 888 491,25 - - - Spain - United Kingdom - France - Italy - Sweden - France - Germany - - - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Corinna Hahn - Tel.: +49 681 95 92 3362 - Fax: +49 681 95 92 3370 - - Bio-electronic microsystems hold promise for repairing the damaged central nervous system (CNS). However, this potential has not been developed because their implantation inflicts additional neural injury, and ensuing - inflammation and fibrosis compromise device functionality. In Neurofibres we want to achieve a breakthrough in “Neuroregenerative Bio-electronics”, developing dual-function devices that will serve as electroactive scaffolds for CNS regeneration and - neural circuit activation. We engineered electroconducting microfibres (MFs) that add negligible tissue insult while promoting guided cell migration and axonal regeneration in rodents with spinal cord injury (SCI). The MFs also meet the challenge of - probe miniaturisation and biofunctionalisation for ultrasensitive recording and stimulation of neural activity. An interdisciplinary consortium composed of neuroscientists, medical specialists, researchers in biomaterials, protein engineering, - physics, and electrical and mechanical engineering, together with a company specialised in fabrication of microcables and microconnectors, will join efforts to design, develop, and test the MFs and complementary technology (microfibre - functionalisation, assembling, and electronic interconnection), in order to produce a biologically safe and effective bio-electronic system for the treatment of SCI. This goal will be achieved through five specific objectives: - - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.2."> - - - FETPROACT-01-2016 - FET Proactive: emerging themes and communities - - - RIA - Research and Innovation action - - - Spain - - - Neurofibres - - - FETPROACT-2016 - - - 732344 - - - - - POLITECNICO DI MILANO - TECHNISCHE UNIVERSITEIT DELFT - THE UNIVERSITY OF LIVERPOOL - UNIVERSITY OF GLASGOW - - - EUR 3 146 893,92 - - - Network for Innovative Training on ROtorcraft Safety - - - EUR 3 146 893,92 - - - Italy - Netherlands - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Helicopters and the other vertical flight vehicles, like tilt-rotors, compound helicopters, hybrids and rapidly expanding class of easy to fly vertical take-off personal vehicles, are expected to see widespread use in the - future especially as means of transport, exploiting the formidable capability to provide point-to-point connections. - - 2020-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-EJD - European Joint Doctorates - - - Italy - - - NITROS - - - H2020-MSCA-ITN-2016 - - - 721920 - - - - - POLITECNICO DI TORINO - OPTIFLOW - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 794 224,80 - - - Sand Mitigation around Railway Tracks - - - EUR 794 224,80 - - - Italy - France - United Kingdom - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - In the last decade, a growing number of railways and other civil or industrial infrastructures have been designed and/or built in arid regions worldwide. The European Railway Industry is often selected for such projects, - because of its strong overall know-how. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-EID - European Industrial Doctorates - - - Italy - - - SMaRT - - - H2020-MSCA-ITN-2016 - - - 721798 - - - - - POLITECNICO DI TORINO - POLITECNICO DI TORINO - - - EUR 149 526 - - - ToothPic, a large-scale camera identification system based on compressed fingerprints - - - EUR 149 526 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The continuously growing amount of photos posted and distributed over the Internet poses several important problems related to improper use of images, such as exploiting them for commercial purposes, re-posting others’ photos - without consent or infringing copyright, posting photos containing unethical or illegal contents, and so forth. Camera identification, which refers to identifying which digital imaging sensor has shot a given picture, exploiting the fact that each - sensor leaves a unique fingerprint in all pictures, is a key ingredient in the solution to the aforementioned problems. The ToothPic project aims at validating a breakthrough camera identification technology developed during ERC starting grant - “CRISP”. This technology is based on a novel compressed fingerprint format and outperforms state-of-the art techniques by orders of magnitude in terms of storage requirements and identification speed. As a consequence, it enables the deployment of - camera-identification services on an unprecedented scale, paving the way for application to popular image sharing and social media sites. The proof-of-concept will consist in a very high-speed implementation of the camera identification core - functionality, which will be used to validate the capability of the proposed technology to handle scenarios involving 100+ millions of sensor fingerprints, in real time and at a low cost. A set of demo applications, including a public search engine, - taking as input a camera fingerprint or a photo and returning a list of photos acquired by the same camera, will also be implemented in order to raise a broad public interest and attract industries and venture capitalists. Upon successful validation, - a European start-up company named “ToothPic” will be created to commercialise the proposed technology. - - 2017-02-28, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2014 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Italy - - - ToothPic - - - ERC-2014-PoC - - - 665421 - - - - - THE QUEEN'S UNIVERSITY OF BELFAST - DEUTSCHES ZENTRUM FUER LUFT - UND RAUMFAHRT EV - PANEPISTIMIO PATRON - UNIVERSITY OF ULSTER - SWEREA SICOMP AB - SHORT BROTHERS PLC - CENTRO RICERCHE FIAT SCPA - UNIVERSITY OF LIMERICK - POLITECNICO DI TORINO - - - EUR 3 933 281,52 - - - Improving the crashworthiness of composite transportation structures - - - EUR 3 933 281,52 - - - United Kingdom - Germany - Greece - United Kingdom - Sweden - United Kingdom - Italy - Ireland - Italy - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The European aerospace, automotive, and rail industries are committed to improving their energy efficiency to meet targets set within the EU’s climate, energy and transport policies. This is motivating the increased use of - lightweight composite materials in lieu of heavier metallics. To implement this transition, these industries must reach, at least, the same level of crash performance achieved with metals, but at significantly lower weight and without increasing - cost. This is viewed by industry as an exceptionally challenging goal and will require highly trained engineers, versed in the myriad aspects of designing cost-effective, crashworthy composites structures, and capable of harnessing the latest - research developments in the fast-changing world of composites. The ICONIC ETN aims to cultivate such a new generation of young engineers; comfortable and fluent in the integration and exploitation of knowledge from fields as diverse as materials - science, chemistry, computational methods, solid and damage mechanics, textile technology, structural design and optimisation. These researchers will acquire the skills to enable the sustainable and economically-viable design of a new generation of - highly efficient, lightweight transportation composite structures that will provide the maximum protection to occupants through superior crashworthiness. 15 Early Stage Researchers (ESRs) will be recruited to take up posts, across the UK, Ireland, - Greece, Germany, Italy and Sweden, in an innovative, multidisciplinary and intersectoral structured research and training programme. ICONIC is supported by a strong consortium from academia, large industrial enterprises and innovative SMEs. A - comprehensive training and secondment programme (including joint supervision and industrial mentoring) will equip researchers with additional transferable skills to ensure future employability and career progression. - - 2020-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - ICONIC - - - H2020-MSCA-ITN-2016 - - - 721256 - - - - - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - - - EUR 159 460,80 - - - Crosstalk between microbiota metabolites and immune cells, the missing link to brain damage. - - - EUR 159 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - Stroke is the second most common cause of death in Europe: accounting for almost 1.1 million deaths each year, with only 15% of stroke patients being eligible for a specific treatment. I have reported–in this year Nature - Medicine’s April issue–that microbiota influences the severity of stroke injury through an impaired intestinal immune function. These findings revealed for the first time the critical implication of the microbiota as a novel and relevant prospective - target for therapeutic strategies in stroke. However, the development of efficient therapies requires to identify which bacterial species and bacterial products are involved in the modulation of the immune response and thereby influence stroke - outcome. - - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - MetaBiota - - - H2020-MSCA-IF-2016 - - - 753893 - - - - - POLITECNICO DI TORINO - POLITECNICO DI TORINO - INSTITUT MINES-TELECOM - - - EUR 2 000 000 - - - from Cubic To Linear complexity in computational electromagnetics - - - EUR 2 000 000 - - - Italy - Italy - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Computational Electromagnetics (CEM) is the scientific field at the origin of all new modeling and simulation tools required by the constantly arising design challenges of emerging and future technologies in applied - electromagnetics. As in many other technological fields, however, the trend in all emerging technologies in electromagnetic engineering is going towards miniaturized, higher density and multi-scale scenarios. Computationally speaking this translates - in the steep increase of the number of degrees of freedom. Given that the design cost (the cost of a multi-right-hand side problem dominated by matrix inversion) can scale as badly as cubically with these degrees of freedom, this fact, as pointed out - by many, will sensibly compromise the practical impact of CEM on future and emerging technologies. - - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Italy - - - 321 - - - ERC-2016-COG - - - 724846 - - - - - ARISTOTELIO PANEPISTIMIO THESSALONIKIS - AGRITEST SRL - BETA FIDAN DOKU KULTURU ISLAH ARGEZIRAAT TARIM SULAMA HAYVANCILIK GIDA TURIZM INSAAT SANAYI TICARET LIMITED SIRKETI - BIOREBA AG - CONSIGLIO NAZIONALE DELLE RICERCHE - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - XILOGIANNIS BROSS UN.CO - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - LIFESEQUENCING SL - MUSTAFA KEMAL UNIVERSITY - NAMIK KEMAL UNIVERSITESI*NAMIK KEMAL UNIVERSITY NKU - INSTITUTO VALENCIANO DE INVESTIGACIONES AGRARIAS - UNIVERSITA DEGLI STUDI DELLA BASILICATA - INSTITUTE OF PLANT PROTECTION CHINESE ACADEMY OF AGRICULTURE SCIENCES - INSTITUTO SUPERIOR POLITECNICO DO KWANZA SUL - UNIVERSITY OF PRETORIA - - - EUR 630 000 - - - Virus free Fruit Nurseries - - - EUR 787 500 - - - Greece - Italy - Turkey - Switzerland - Italy - France - Greece - Greece - Spain - Turkey - Turkey - Spain - Italy - China - Angola - South Africa - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Fruit trees and grapevine are propagated vegetatively and are often grafted. As a result they suffer from a high number of pathogens such as viruses and viroids, a number of which are causing severe yield losses and reduce the - productive life of the affected plants. As these pathogens cannot be controlled by the application of chemicals, the most efficient way to combat them is the production and commercialization of high quality pathogen-tested propagative material. - Nevertheless, this procedure is not simple and both academia and private sectors are working towards its improvement. In this direction was built the herein interdisciplinary proposal which brings together academia and private companies to - collaborate through their expertise on the following objectives: 1) to identify new viral and viroid strains or species affecting fruit trees and grapevine, 2) to optimise existing and develop novel detection methods and 3) to improve propagation and - sanitation methods for producing high quality (virus-tested) plant material of fruit trees and grapevine. In this project diagnostic tools that are currently used in certification programs will be combined with cutting edge technologies such as NGS - and Nanobodies. The project has eight academic partners within the EU and associated countries, three within Third Countries and five non-academic partners. The knowledge obtained will be shared among the partners of the proposal and further - disseminated to academic institutions, nurseries and other private sectors. Most importantly training of a new generation of researchers will be done in close contact to the needs of both industrial and academic sectors. In conclusion, the results of - this proposal will enrich the knowledge on viruses/viroids associated with different diseases, improve the sensitivity of their detection methods, lead to new detection products and further contribute to the improvement of the disseminated - propagative material of fruit trees and grapevine. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Greece - - - VirFree - - - H2020-MSCA-RISE-2016 - - - 734736 - - - - - POLITECNICO DI TORINO - POLITECNICO DI TORINO - - - EUR 150 000 - - - Integrated Smart Device for Emergency Management - - - EUR 150 000 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The project IDEAL SENSOR is developing a wearable wrist band device and a customized structural health monitoring (SHM) system for managing emergencies. The proposed system provides a comprehensive solution for indoor - localization, healthcare monitoring, and other general purpose services (fitness, entertainment, health, etc.). Moreover, an infrastructure based on the structural health monitoring will be developed which include all the functionality of standard - Structural Health Monitoring (SHM) systems (environmental monitoring, health assessment, etc.), but it performs also indoor localization. In detail, the system is composed of different environmental monitoring sensors (humidity and temperature), body - signal monitoring (heart rate, body temperature, humidity, location and images), communication modules (radio frequency (RF) transceiver, GPRS/GSM, GPS and Bluetooth low energy), OLED display. Currently , the prototype has been developed and tested - in a STM Nucleo-F401 board which is a developing board provided by STMicroelectronics commonly used for rapid prototyping. In order to commercialize the prototype and make it a feasible product, the current developed system should be redesigned and - customized based on our needs and requirements. The electrical parts will be redesigned completely and the best available solutions (price and quality) for each sub-module and components will be used. Moreover, by miniaturizing the prototype and - designing a user friendly package and software, it will get the shape of a real smart watch with more features with respect to the current ones. - - 2018-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Italy - - - IDEAL SENSOR - - - ERC-2016-PoC - - - 727261 - - - - - POLITECNICO DI TORINO - POLITECNICO DI TORINO - - - EUR 1 222 500 - - - Coping with water scarcity in a globalized world - - - EUR 1 222 500 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - We intend to set up a new globalized perspective to tackle water and food security in the 21st century. This issue is intrinsically global as the international trade of massive amounts of food makes societies less reliant on - locally available water, and entails large-scale transfers of virtual water (defined as the water needed to produce a given amount of a food commodity). The network of virtual water trade connects a large portion of the global population, with 2800 - km3 of virtual water moved around the globe in a year. We provide here definitive indications on the effects of the globalization of (virtual) water on the vulnerability to a water crisis of the global water system. More specifically, we formulate - the following research hypotheses: - - - 2020-06-30, ongoing project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Italy - - - CWASI - - - ERC-2014-CoG - - - 647473 - - - - - POLITECNICO DI TORINO - POLITECNICO DI TORINO - - - EUR 1 489 219 - - - Hybrid immune-eluding nanocrystals as smart and active theranostic weapons against cancer - - - EUR 1 489 219 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Nanomedicine tools for cancer treatment comprise many nanosized systems, so far developed with smart functions such as efficient drug delivery and cell targeting abilities. However they remain still undercharacterized in terms - of immunogenicity, potential toxicity due to the materials itself or the unwanted release of drugs. To overcome these challenges this project aims to develop a new generation of multifunctional therapeutic and diagnostic (thus theranostics) - nanosystems displaying non-immunogenicity, improved cancer treatment, cell imaging, and high safety for the hosting organism. The innovative concept behind this approach relies on a core-shell nanosystem with a therapeutically active core, i.e. a - TrojaNanoHorse (TNH), here validated against leukaemia. The injectable TNH have a lipid bilayer shell derived from autologous cancer cell membrane, naturally non-immunogenic. The hemocompatibility, antithrombogenicity, and targeting ability with - antibodies toward malignant blood cells will be proved during this project. Studies will show the zinc oxide nanocrystal core activation developing toxic reactive oxygen species (ROS) for cancer killing, and its green fluorescence emission. The whole - TNH would go beyond the state-of-the-art due to its nature-derived biomimetic shell, absence of drugs, its safety and biodegrading fate, and green luminescent emissions for diagnosis. This project will also develop novel set-up for non-immunogenic - therapy and diagnosis, impacting on future technology, new standardized protocols for nanomaterial safety assessment, and study chemical and biological mechanism of ROS development effects on cancer cell. Achieving the ultimate goal of a - multifunctional TNH will require multidisciplinary expertise in chemistry, material science, biology, medicine and engineering, opening new horizons as nanomedicine tools for efficient cancer therapy with strong scientific, technological and - socio-economic benefits. - - 2021-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Italy - - - TROJANANOHORSE - - - ERC-2015-STG - - - 678151 - - - - - POLITECNICO DI TORINO - - - EUR 247 728,60 - - - Ultra-Low Power and Highly-Scalable Interfaces for the Internet of Things - - - EUR 247 728,60 - - - Italy - - - Higher or Secondary Education Establishments - - The era of the Internet of Things (IoT), in which every physical entity includes power-autonomous embedded electronics, capturing relevant information by sensors and interacting with objects and humans in a globally - interconnected network, is bringing about new challenges in Integrated Circuit (IC) design. The performance of ICs in terms of integration density, power consumption and cost, in fact, is the only limiting factor to the feasibility and/or to the - widespread diffusion of IoT-based solutions. - - 2020-01-31, ongoing project - - - 2017-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Italy - - - ULPIoT - - - H2020-MSCA-IF-2015 - - - 703988 - - - - - POLITECNICO DI TORINO - POLITECNICO DI TORINO - - - EUR 1 271 138 - - - Integrated DEsign and control of Sustainable CommUnities during Emergencies - - - EUR 1 271 138 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Integrated DEsign and control of Sustainable CommUnities during Emergencies - - 2020-10-31, ongoing project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Italy - - - IDEal reSCUE - - - ERC-2014-STG - - - 637842 - - - - - POLITECNICO DI TORINO - - - EUR 197 720,10 - - - ECOsystem services for resilient and sustainable cities: an ecohydrological approach for Green Urban Spaces - - - EUR 197 720,10 - - - Italy - - - Higher or Secondary Education Establishments - - For the first time in recorded history the majority of people live in cities and the increasing urbanization modifies their mass, momentum, and energy budgets: in the next decades redevelopment, densification, population - increase and demographic shift, as well as climate change will potentially impact the production and consumption of urban ecosystem services. - - - 2018-11-14, ongoing project - - - 2016-08-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Italy - - - ECO.G.U.S. - - - H2020-MSCA-IF-2015 - - - 701914 - - - - - POLITECNICO DI TORINO - - - EUR 244 269 - - - Theranostic Injectable Hydrogel for Glioblastoma - - - EUR 244 269 - - - Italy - - - Higher or Secondary Education Establishments - - Glioblastoma multiforme (GBM) is the most frequent brain tumor in adults and is characterized by invariably fatal prognosis. Although the incidence of GBM is less than 10 to 100,000, the median survival of approximate 1 year - from diagnosis makes it a considerable socio-economic burden. The presence of biological barriers for effective drug transport to the brain, the strong migrating-ability of the tumor and its rapid evolution into more aggressive and - treatment-resistant variants, make GBM extremely hard to treat with traditional systemic chemotherapy. The HyGlio project proposes an ambitious bottom-up approach to build a multifunctional tool for long-term imaging and treatment of GBM, combining - multiple treatment strategies, patient-specificity, and BBB bypassing in an all-in-one system. The system combines the advantages of: (i) Intracranial treatment, which maximizes efficacy while minimizing side effects; (ii) mild gelling conditions of - the hydrogel, which reduce potential damages to the healthy tissue; (iii) increased drug penetration and selectivity due to the use of targeted polymer nanoparticles; (iv) Inhibition of molecular mechanisms involved in GBM spreading and - aggressiveness; (iv) theranostic potential, due to the presence of magnetic resonance imaging, agents for rapid therapy adjustment according to patient’s needs. - - 2019-09-29, ongoing project - - - 2016-09-30 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Italy - - - HyGlio - - - H2020-MSCA-IF-2014 - - - 658665 - - - - - UNIWERSYTET MEDYCZNY W BIALYMSTOKU - - - EUR 1 569 600 - - - International Interdisciplinary PhD studies in Biomedical Research and Biostatistics. Supporting the career and training in omic-based research and biostatistics by inter-national and-sectoral mobility - - - EUR 3 139 200 - - - Poland - - - Higher or Secondary Education Establishments - - The aim of the project is to launch Interdisciplinary PhD Studies in Biomedicine aimed at young aspiring scientists, who will conduct research on life-style diseases and on biostatistics and bioinformatics methods necessary to - process and interpret data obtained in research projects. The studies will provide an outstanding opportunity for in-depth education in high-throughput experimental and computational techniques used in genomics, proteomics, metabolomics and - immunology. 15 PhD students will be involved in scientific projects supervised by excellent researchers, outstanding scientists selected from partner organizations, with a profound expertise and experience in: Cancer/Mutagenesis, Cardiovascular - diseases, Population Medicine and Epidemiology, Diabetes/Obesity, Metabolic and Neurodegenerative diseases, Regenerative medicine, Molecular Biology, Genomics, Protein Analysis and Proteomics, Metabolomics/Lipidomics, Immunology and Experimental - Medicine. They will be employed at Medical University of Bialystok. The development of doctoral students' research potential will be based also on internships, short research visits, conferences and trainings at the partner institutions: CEMBIO San - Pablo University, Vienna Biocenter, Spanish National Center for Cardiovascular Research CNIC, Bialystok University of Technology and CenStat at Hasselt University. Industry partner organizations: Agilent Technology, deCODE, ideas4biology and Warsaw - Genomics will invite PhD students for scientific visits, to familiarize young researchers with the tools and methods of work and organizational environment in the company. Industry providing their know-how will educate, and prepare their potential - employees with high qualifications to get job in the close future. Best young scientists from the beginning of their academic career will be able to gain scientific independence and will have huge motivation to become more involved and creative in - the research projects carried out thanks to COFUNDing the project by EC. - - 2023-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2016 - Co-funding of regional, national and international programmes - - - MSCA-COFUND-DP - Doctoral programmes - - - Poland - - - ImPRESS - - - H2020-MSCA-COFUND-2016 - - - 754432 - - - - - UNIVERSITA DEGLI STUDI DI TRENTO - PANEPISTIMIO PATRON - UNIVERSITA DEGLI STUDI DEL SANNIO - UNIVERZA V LJUBLJANI - POLITECHNIKA SLASKA - UNIVERSITA DEGLI STUDI ROMA TRE - INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE RENNES - ARCELORMITTAL BELVAL & DIFFERDANGE SA - COLUMBIAN CARBON EUROPA SRL - VCE VIENNA CONSULTING ENGINEERS ZT GMBH - - - EUR 3 393 811,98 - - - EXTREME LOADING ANALYSIS OF PETROCHEMICAL PLANTS AND DESIGN OF METAMATERIAL-BASED SHIELDS FOR ENHANCED RESILIENCE - - - EUR 3 393 811,98 - - - Italy - Greece - Italy - Slovenia - Poland - Italy - France - Luxembourg - Italy - Austria - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The tremendous impact of natural hazards, such as earthquakes, tsunamis, flooding, etc, which triggered technological accidents, referred to as natural-technological (NaTech) events, was demonstrated by: i) the recent Tohoku - earthquake and the following Fukushima disaster in 2011; ii) the UK’s 2015 winter floods which topped £5bn, with thousands of families and businesses that faced financial problems because of inadequate or non-existent insurance. The NaTech problem is - quite relevant as up to 10% of industrial accidents, involving the release of Chemical, Biological, Radiological, Nuclear and high-yield Explosives (CBRNE) substances, were triggered by natural hazards. To implement and support the Seveso II - Directive 2012/18/EU which regulates the control of major accident hazards involving dangerous substances, XP-RESILIENCE intends to establish a network of individual research projects working towards Advanced Modelling and Protection –via - metamaterial-based isolators/layouts- of Complex Engineering Systems for Disaster Reduction and Resilient Communities. In fact, today there is a stronger need than ever to grow researchers that combine a robust academic foundation in - reliability/resilience with practical experiences, technological expertise with awareness of the socio-economical context and conviction to furthering research with an entrepreneurial spirit. Hence, the objective of XP-RESILIENCE is to offer - innovative research training ground as well as attractive career development and knowledge exchange opportunities for Early Stage Researchers (ESRs) through cross-border and cross-sector mobility for future growth in Europe. XP-RESILIENCE is an - inter/multi-disciplinary and intersectoral programme as it includes seven academic partners, one Institute of Applied Science and seven private companies from ten different European countries. - - 2020-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Italy - - - XP-RESILIENCE - - - H2020-MSCA-ITN-2016 - - - 721816 - - - - - UNIVERSITA DEGLI STUDI DI TORINO - POLITECNICO DI TORINO - UNIVERSITA DEGLI STUDI DEL PIEMONTE ORIENTALE AMEDEO AVOGADRO - UNIVERSITA DEGLI STUDI DI SCIENZE GASTRONOMICHE - CENTROSCIENZA ONLUS ASSOCIAZIONE - CREATIVA IMPRESA DI COMUNICAZIONE SRL - - - EUR 178 250 - - - Cementing Links between Science and society toward Engagement and Responsibility - - - EUR 271 750 - - - Italy - Italy - Italy - Italy - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The European Researchers’ Night (ERN) has become an annual tradition in Piedmont thanks to an extraordinary 10 years experience that has made citizens of all ages eagerly awaiting this appointment with the scientific vocation - of our district and the European Commission. - - 2018-01-01, closed project - - - 2016-05-02 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.5."> - - - MSCA-NIGHT-2016 - European Researchers' Night - - - CSA - Coordination and support action - - - Italy - - - CLoSER - - - H2020-MSCA-NIGHT-2016 - - - 722749 - - - - - FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION - - - EUR 175 419,60 - - - Detection of visual motion in the cortex - - - EUR 175 419,60 - - - Switzerland - - - Research Organisations - - Direction selectivity is a feature of selected neurons in the visual cortex that is conserved in evolution. The emergence of cortical direction selectivity has been extensively studied but its circuit mechanism is still - debated. My goal is to understand the circuit mechanism of cortical direction selectivity that is independent of retinal direction selectivity. I plan to approach this by using two animal models in which retinal direction selectivity has been - disrupted. I will investigate the neuronal circuits of those cortical direction-selective neurons which retain their specificity in these animal models by performing single-cell-initiated functionalized rabies tracing and single-cell - electrophysiological recordings. I will ask the three following questions: Do axon terminals of the principal cells of the lateral geniculate nucleus (LGN) fully lose direction selectivity after the abolishment of retinal direction selectivity, or - could cortical feedback from layer 6 entrain direction selectivity in a subset of LGN cell axon terminals? What is the synaptic input profile underlying retina-independent cortical direction selectivity in pyramidal neurons? What is the contribution - of the local presynaptic networks to the direction-selective tuning of pyramidal neurons with retina-independent cortical direction selectivity? This work will provide insights into how cortical selectively for environmental features arises. - - 2020-08-31, Grant Agreement terminated - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - Cortical circuits - - - H2020-MSCA-IF-2016 - - - 747836 - - - - - UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN - ARISTOTELIO PANEPISTIMIO THESSALONIKIS - UNIVERSITY OF ULSTER - OULUN YLIOPISTO - SALUMEDIA TECNOLOGIAS SL - Chambre de Commerce et d'Industrie de Grenoble - BEACON HOSPITAL SANDYFORD LIMITED - PHILIPS ELECTRONICS NEDERLAND B.V. - - - EUR 3 950 971,20 - - - Connected Health Early Stage Researcher Support System - - - EUR 3 950 971,20 - - - Ireland - Greece - United Kingdom - Finland - Spain - France - Ireland - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Changing demographics and increasing pressure on health related resources mean that new models of care must be found. Fortunately, technology developments and increasing digital literacy mean that we can now put the correct - information in the correct hands at the correct time. This is connected health and it allows patients, clinicians, and planners to make better decisions. Ultimately, these decisions can save lives, save money and ensure a better quality of life for - the patient during and after treatment. - - 2019-08-31, ongoing project | - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Ireland - - - CHESS - - - H2020-MSCA-ITN-2015 - - - 676201 - - - - - CENTRE TECNOLOGIC FORESTAL DE CATALUNYA - UNIVERSIDAD POLITECNICA DE MADRID - Instituto Superior de Agronomia - SVERIGES LANTBRUKSUNIVERSITET - ITA-SUOMEN YLIOPISTO - ALBERT-LUDWIGS-UNIVERSITAET FREIBURG - UNIVERSIDADE DE EVORA - CENTRO AGRONOMICO TROPICAL DE INVESTIGACION Y ENSENANZA CATIE - The Pennsylvania State University - UNIVERSITY OF WASHINGTON - PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE - UNIVERSIDADE DE SAO PAULO - UNIVERSIDAD DE CHILE - Pacific Northwest Research Station - - - EUR 1 885 500 - - - Models and decision SUpport tools for integrated FOrest policy development under global change and associated Risk and UNcertainty - - - EUR 1 885 500 - - - Spain - Spain - Portugal - Sweden - Finland - Germany - Portugal - Costa Rica - United States - United States - Chile - Brazil - Chile - United States - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - Forest policy and decision makers are challenged by the need to balance the increasing demand for forest-based services (e.g. recreation, protection, conservation) and wood-based products (e.g. timber, fuelwood) with the - foreseen scarcity of supply in different situations as for example disturbances (e.g. wildfires, droughts). Under these circumstances research on the impacts of different disturbances on the supply of services and goods is needed. To achieve these - multipurpose forest managements and to integrate risk and uncertainty, New tools and models are needed. Furthermore, these tools and models may help to develop new policies that target the achievement of certain level of services while sustaining a - certain level of goods supply. This project will take advantage of the knowledge on these topics in European and American organizations. It will further serve to exchange and generate knowledge on multipurpose forests, addressing risk and uncertainty - as well as to strengthen research collaboration through active networking, staff exchange and dissemination activities between the participants. - - 2020-01-31, ongoing project - - - 2016-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Spain - - - SuFoRun - - - H2020-MSCA-RISE-2015 - - - 691149 - - - - - AALTO-KORKEAKOULUSAATIO - ELEKTA OY - HELSINGIN JA UUDENMAAN SAIRAANHOITOPIIRIN KUNTAYHTYMÄ - PHYSIKALISCH-TECHNISCHE BUNDESANSTALT - TECHNISCHE UNIVERSITAET ILMENAU - UNIVERSITA DEGLI STUDI GABRIELE D'ANNUNZIO DI CHIETI-PESCARA - Teknologian tutkimuskeskus VTT Oy - - - EUR 3 998 793 - - - Breaking the Nonuniqueness Barrier in Electromagnetic Neuroimaging - - - EUR 3 998 793 - - - Finland - Finland - Finland - Germany - Germany - Italy - Finland - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - By combining accurate magnetic measurements of neural activity with near-simultaneous high-definition measurements of cerebral structure – provided by novel methods in ultra-low-field magnetic resonance imaging (ULF MRI ) – we - will be able to image the dynamics of human brain function at unprecedented resolution and reliability. BREAKBEN will achieve a revolution in neuroimaging; we aim at breaking the barrier for measurement of neuronal currents by ULF MRI (neural current - imaging; NCI) as well as breaking the nonuniqueness barrier for magnetoencephalography (MEG) by combining it with ULF MRI and accurately presented a priori information. A key aspect in utilizing the a priori information is injected current density - imaging (CDI), which will inform us about the individual conductivity structure of the head. Using novel verification and validation approaches, we will demonstrate the unique advantages of these multimodal techniques. These breakthroughs will result - in completely different workflows in brain imaging, also suitable for clinical use. We believe that we are at the edge of a qualitative technology jump with ULF MRI, its applications and combinations. This will lead to a wealth of new applications - and revolutionize the way we do magnetism-based measurements of the nervous system. Europe has the unique chance to lead this revolution. - - 2018-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-1-2014 - FET-Open research projects - - - RIA - Research and Innovation action - - - Finland - - - BREAKBEN - - - H2020-FETOPEN-2014-2015-RIA - - - 686865 - - - - - HASKOLI ISLANDS - HASKOLI ISLANDS - - - EUR 1 998 543,75 - - - The Genetics of Morbidity and Survival in Response to Significant Life Stressors - - - EUR 1 998 545 - - - Iceland - Iceland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Significant life stressors – including death of loved ones, being diagnosed with a life-threatening illness, and exposure to natural disasters or violence – are well-documented risk factors of ill health, disability and - premature mortality. Why some individuals remain healthy while others remiss to adverse symptoms, disease or death after exposure to such life stressors remains unclear. The overarching aim of this research program is to advance current understanding - of the potential genetic contribution to varying trajectories of health following exposure to significant life stressors. - - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Iceland - - - StressGene - - - ERC-2016-COG - - - 726413 - - - - - POLITECNICO DI TORINO - POLITECNICO DI TORINO - - - EUR 1 977 500 - - - Biomimetic trick to re-balance Osteblast-Osteoclast loop in osteoporoSis treatment: a Topological and materials driven approach - - - EUR 1 977 500 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - One out of 5 people in their fifties will experience a bone fracture due to osteoporosis (OP)-induced fragility in their lifetime. The OP socio-economic burden is dramatic and involves tens of millions of people in the EU, - with a steadily increasing number due to population ageing. Current treatments entail drug-therapy coupled with a healthy lifestyle but OP fractures need mechanical fixation to rapidly achieve union: the contribution of biomaterial scientists in this - field is still far from taking its expected leading role in cutting-edge research. Bone remodelling is a well-coordinated process of bone resorption by osteoclasts followed by the production of new bone by osteoblasts. This process occurs - continuously throughout life in a coupling with a positive balance during growth and negative with ageing, which can result in OP. We believe that an architecture driven stimulation of the osteoclast/osteoblast coupling, with an avant-garde focus on - osteoclasts activity, is the key to success in treating unbalanced bone remodelling. We aim to manufacture a scaffold that mimics healthy bone features which will establish a new microenvironment favoring a properly stimulated and active population - of osteoclasts and osteoblasts, i.e. a well-balanced bone cooperation. After 5 years we will be able to prove the efficacy of this approach. A benchmark will be set up for OP fracture treatment and for the realization of smart bone substitutes that - will be able to locally “trick” aged bone cells stimulating them to act as healthy ones. BOOST results will have an unprecedented impact on the scientific research community, opening a new approach to set up smart, biomimetic strategies to treat - aged, unbalanced bone tissues and to reduce OP-associated disabilities and financial burdens. - - 2021-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Italy - - - BOOST - - - ERC-2015-CoG - - - 681798 - - - - - POLITECNICO DI TORINO - - - EUR 180 277,20 - - - Flexible Optical Networks – Time Domain Hybrid QAM: DSP and Physical Layer Modelling - - - EUR 180 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - The delivery of fast Internet connections all over Europe is a primary goal of Horizon 2020. In order to avoid the upcoming capacity crunch on transport optical networks, there is an urgent need for a strong investment in the - research and development of future-proof optical broadband infrastructures. The Flex-ON project will investigate new technological paradigms in terms of signal generation, digital processing and control-plane management for novel flexible and - high-capacity transport optical networks. The primary technical objective of the project is to develop and implement a flexible transceiver prototype with intelligent reconfigurability and arbitrarily low bit-rate granularity. The development of this - technology will enable to increase the network capacity and the spectral/energy efficiency, while providing a future-proof flexible solution for an increasingly heterogeneous global network. - - 2017-10-15, closed project - - - 2015-10-16 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - Flex-ON - - - H2020-MSCA-IF-2014 - - - 653412 - - - - - MAX PLANCK INSTITUT FUR EISENFORSCHUNG GMBH - - - EUR 159 460,80 - - - Designing novel smart sensor interfaces based on a biologically abundant peptide motif: coiled-coils - - - EUR 159 460,80 - - - Germany - - - Research Organisations - - Smart interfaces alter their properties in response to an external trigger. Such devices open exciting opportunities for novel technologies with manifold applications. Electrical fields pose easily controllable triggers for - smart interfaces and even allow a precise 'digital' switching between 'on' and 'off' states. The research project ‘smartCC’ will employ a biologically abundant class of biomacromolecules – coiled-coil peptides – to prepare smart selective interfaces, - whose ability to specifically bind targets can be switched reversibly. Moreover, the produced interface will constitute a highly sensitive sensor by application of the attenuated total reflection infrared reflection technique. The variability of - coiled-coils, employed in numerous biological systems, will also extend the potential application bandwidth of smart interfaces significantly. Molecular details of the switching and binding behaviour of the coiled-coils at the interface will be - studied to test the feasibility of the envisioned working principle. Furthermore, the novel devices will be tested for an application with industrial relevance. To reach the goals of ‘smartCC’ a highly interdisciplinary approach is chosen that - includes cooperation between three academic and one non-academic European partners. Thus, the implementation of this project will support bringing an emerging technology towards an economical benefit, foster intra European collaborations and mobility - as well as strengthen Europe’s scientific sector. - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - smartCC - - - H2020-MSCA-IF-2015 - - - 705857 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 183 454,80 - - - Information from Symbols and Illustrations: how to get it without vision - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - In everyday life individuals are bombarded with symbols and illustrations: ‘poisonous’, ‘flammable’, ‘fire evacuation route’ etc.; however this life-saving information is not accessible to all of us. - - 2017-08-31, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - InSIght - - - H2020-MSCA-IF-2014 - - - 657440 - - - - - POLITECNICO DI TORINO - POLITECNICO DI TORINO - - - EUR 1 404 132 - - - Design, manufacturing and control of INterfaces in THERMally conductive polymer nanocomposites - - - EUR 1 404 132 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This proposal addresses the design, manufacturing and control of interfaces in thermally conductive polymer/graphene nanocomposites. - - - 2020-02-29, ongoing project - - - 2015-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Italy - - - INTHERM - - - ERC-2014-STG - - - 639495 - - - - - THE UNIVERSITY OF NOTTINGHAM - UNIVERSITY OF BATH - POLITECNICO DI TORINO - TECHNISCHE UNIVERSITEIT DELFT - ISTITUTO NAZIONALE DI GEOFISICA E VULCANOLOGIA - FUGRO INTERSITE BV - GEO++ GESELLSCHAFT FUR SATELLITENGESTUTZTE GEODATISCHE UND NAVIGATORISCHE TECHNOLOGIEN MBH - NOVELTIS SAS - DEIMOS ENGENHARIA S.A. - - - EUR 3 386 593,80 - - - Training REsearch and Applications network to Support the Ultimate Real time high accuracy EGNSS solution - - - EUR 3 386 593,80 - - - United Kingdom - United Kingdom - Italy - Netherlands - Italy - Netherlands - Germany - France - Portugal - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - TREASURE will provide specialist training in the strategic and emerging area of European GNSS. - - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - TREASURE - - - H2020-MSCA-ITN-2016 - - - 722023 - - - - - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 1 497 257 - - - Vibronic control of organic electronic devices - - - EUR 1 497 257 - - - United Kingdom - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Organic electronics (OE) is an expanding research field that exploits the electronic functionalities of organic molecules to make them robust and cost-efficient building blocks for future electronic devices. Due to the ‘soft’ - character of organic materials, their electronic properties are defined by vibronic coupling (VC) phenomena which are a result of the interaction between electron and nuclear dynamics of the molecule. - - 2020-05-31, ongoing project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - VIBCONTROL - - - ERC-2014-STG - - - 639750 - - - - - ASSOCIATION POUR LA RECHERCHE ET LE DEVELOPPEMENT DES METHODES ET PROCESSUS INDUSTRIELS - ASSOCIATION POUR LA RECHERCHE ET LE DEVELOPPEMENT DES METHODES ET PROCESSUS INDUSTRIELS - CENTRE HOSPITALIER UNIVERSITAIRE SAINT ETIENNE - CHU - - - EUR 1 999 396 - - - Localization in biomechanics and mechanobiology of aneurysms: Towards personalized medicine - - - EUR 1 999 396 - - - France - France - France - - - Research Organisations - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - Rupture of Aortic Aneurysms (AA), which kills more than 30 000 persons every year in Europe and the USA, is a complex phenomenon that occurs when the wall stress exceeds the local strength of the aorta due to degraded - properties of the tissue. The state of the art in AA biomechanics and mechanobiology reveals that major scientific challenges still have to be addressed to permit patient-specific computational predictions of AA rupture and enable localized repair of - the structure with targeted pharmacologic treatment. A first challenge relates to ensuring an objective prediction of localized mechanisms preceding rupture. A second challenge relates to modelling the patient-specific evolutions of material - properties leading to the localized mechanisms preceding rupture. Addressing these challenges is the aim of the BIOLOCHANICS proposal. We will take into account internal length-scales controlling localization mechanisms preceding AA rupture by - implementing an enriched, also named nonlocal, continuum damage theory in the computational models of AA biomechanics and mechanobiology. We will also develop very advanced experiments, based on full-field optical measurements, aimed at - characterizing localization mechanisms occurring in aortic tissues and at identifying local distributions of material properties at different stages of AA progression. A first in vivo application will be performed on genetic and pharmacological - models of mice and rat AA. Eventually, a retrospective clinical study involving more than 100 patients at the Saint-Etienne University hospital will permit calibrating estimations of AA rupture risk thanks to our novel approaches and infuse them into - future clinical practice. Through the achievements of BIOLOCHANICS, nonlocal mechanics will be possibly extended to other soft tissues for applications in orthopaedics, oncology, sport biomechanics, interventional surgery, human safety, cell biology, - etc. - - 2020-04-30, ongoing project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - France - - - BIOLOCHANICS - - - ERC-2014-CoG - - - 647067 - - - - - THE UNIVERSITY OF WARWICK - THE UNIVERSITY OF WARWICK - UNIVERSITA DELLA SVIZZERA ITALIANA - ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA - - - EUR 2 492 033 - - - Diversity and Performance: Networks of Cognition in Markets and Teams - - - EUR 2 492 033 - - - United Kingdom - United Kingdom - Switzerland - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Contemporary organizations face three interrelated, but analytically distinguishable, challenges. First, they should be alert to mistakes that could be catastrophic. Second, they need to allocate attention, especially to - correct past mistakes and to make accurate predictions about future developments. Third, they should be innovative, able to stand out from existing categories while being recognized as outstanding. This project investigates these cognitive challenges - with the aim of developing a comprehensive sociological approach to study the social properties of cognition. Research on error detection, attention allocation, and recognizant innovation will be conducted in three distinct settings strategically - chosen so the scale and complexity of the performance challenges increases across the cases. The research question that cuts across the socio-cognitive challenges asks whether and how diversity contributes to performance. 1) We first test whether - social context, understood at the most basic level as the composition of a small collectivity, affects the cognitive activity of pricing. To do so, I use experimental market methods to test whether ethnic and gender diversity deflate price bubbles by - disrupting herding behaviour. 2) The second study tests how the social structure of attention affects valuation. The activities involve error correction and accuracy of prediction in estimates by securities analysts; the method is two-mode network - analysis; and the timing, intensity, and diversity of attention networks are the effects to be tested. 3) Whereas my first two tests examine relations among competitors, my third examines relations within and across collaborative teams. In studying - the network properties of creativity, the challenge is recognizant innovation, the activity involves recording sessions in the field of music, the method is cultural network analysis, and the effects to be tested are the combined effects of stylistic - diversity and social structure. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - BLINDSPOT - - - ERC-2015-AdG - - - 695256 - - - - - FUNDACIO CENTRE DE RECERCA EN EPIDEMIOLOGIA AMBIENTAL - CREAL - FUNDACION PRIVADA INSTITUTO DE SALUD GLOBAL BARCELONA - - - EUR 170 121,60 - - - Air Pollution, Growing brAin and cognitive disordeR in children - - - EUR 170 121,60 - - - Spain - Spain - - - Research Organisations - Research Organisations - - Air pollution exposure has been associated with adverse effects on cognition in children. However, the impact of air pollution on the structures and functions of the growing brain in children is unknown. The objectives of the - APGAR project are to determine 1) the impact of urban air pollution on the structures and functions of the growing brain in children from the general population, 2) to what extent these structural and functional changes are associated with cognitive - performance in children. The APGAR project is a longitudinal study conducted in 400 school age children from the general population, recruited between 2012 and 2013, in different schools in Barcelona, Spain. Psychometric and air pollution - measurements were conducted weekly during 2 six-week periods: at the beginning of the school year and 9 months later. Neuroimaging (High-resolution 3-dimensional Magnetic Resonance Imaging (MRI), Diffusion Tensor Images, Fluid Attenuation Inversion - Recovery, T2-weighted spin-echo sequences and functional MRI, spectrometry) were also conducted. Interfacing neuroimaging and environmental epidemiology represents an innovative applications of neuroimaging in general population, as previous studies - have focused exclusively on effects based on test scores. Using original statistical methods (combination of supervised machine learning methods, feature selection and regression models), we will examine the impact of air pollution on the brain - structures correlated with cognitive performance in children. Secondly, we will examine whether profiles of brain changes, specifically related to air pollution exposure, are associated with cognition level in participants. This multidisciplinary - project may improve our understanding of the mechanisms that underlie the link between air pollution and cognitive disorder in children, and may lead to public health actions to improve air quality and reduce the burden of disease associated with air - pollution in Europe. - - 2017-10-14, closed project - - - 2015-10-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - APGAR - - - H2020-MSCA-IF-2014 - - - 656294 - - - - - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - - - EUR 164 653,20 - - - House Architecture and Heritage in modern Crete - - - EUR 164 653,20 - - - Greece - - - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - - Cretan minor built heritage dating back to the Venetian and Ottoman periods has until now received scarce attention by scholars and local authorities. The two-year HArchitHeC project (House Architecture and Heritage in modern - Crete) wants to focuses on rural and urban houses of Crete in order to reach three main goals: to perceive the built environment in its materiality and its historical evolution; to study how the evolution and interaction of Venetian and Ottoman - cultural models built up a hybrid architecture in a colonial dimension; and to identify possible strategies for heritage protection by bringing research to the public realm. To do so, an interdisciplinary innovative approach will be used: a - historical study of written sources and an architectural comparative study, by means of an inventory and a comparative study of Venetian and Turkish house prototypes. Such a pilot project aspires to a wider comparative study between Crete and the - nearby regions, starting with other Mediterranean islands (Rhodes and Cyprus at first). - - 2018-05-31, Grant Agreement terminated - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Greece - - - HArchitHeC - - - H2020-MSCA-IF-2015 - - - 705499 - - - - - LUDWIG BOLTZMANN GESELLSCHAFT GMBH - LUDWIG BOLTZMANN GESELLSCHAFT GMBH - - - EUR 1 499 500 - - - Common Oncogenic Mechanisms in Multi-Partner Translocation Families in Acute Myeloid Leukemia - - - EUR 1 499 500 - - - Austria - Austria - - - Research Organisations - Research Organisations - - Acute Myeloid Leukemia (AML) is the most frequent cancer of the blood system, with >80% mortality within 5 years of diagnosis. Straightforward clinical decisions are complicated by the genetic complexity of AML. In - particular, fusion proteins arising from chromosomal aberrations are recurrently found in AML and often act as strong driver oncogenes. In “Multi-Partner Translocation” (MPT) families, one specific gene is fused to many recipient loci. Due to this - modular architecture, MPT families are of particular interest to comparative studies of oncogenic mechanisms. The three most common MPT families in AML represent translocations of the MLL, RUNX1 and NUP98 genes. Despite their clinical significance, - the molecular mechanism of transformation remains unknown for the majority of fusion proteins and it is unclear if transforming mechanisms are conserved within and across different MPT families. - - 2020-05-31, ongoing project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Austria - - - ONCOMECHAML - - - ERC-2014-STG - - - 636855 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - MEDIZINISCHE UNIVERSITAET WIEN - LUDWIG BOLTZMANN GESELLSCHAFT GMBH - Masarykova univerzita - EBERHARD KARLS UNIVERSITAET TUEBINGEN - UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - CHARITE - UNIVERSITAETSMEDIZIN BERLIN - UNIVERSITA DEGLI STUDI DI TORINO - JUSTUS-LIEBIG-UNIVERSITAET GIESSEN - INSTITUT GUSTAVE ROUSSY - GOETEBORGS UNIVERSITET - UNIVERSITAETSKLINIKUM FREIBURG - - - EUR 3 849 199,56 - - - ALK Activation as a target of TRAanslational Science (ALKATRAS): Break free from cancer - - - EUR 3 849 199,56 - - - United Kingdom - Austria - Austria - Czech Republic - Germany - Italy - France - Germany - Italy - Germany - France - Sweden - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This ETN is embedded into an established international research programme; The European Research Initiative on Anaplastic Lymphoma Kinase (ALK)-related malignancies (ERIA; www.erialcl.net) is an existing and functional network - of 13 partners, which will cosset and nurture a cohort of early stage researchers to become confident, competent, independent and well-connected European scientists with excellent career perspectives. ERIA was instigated to coordinate research into - ALK-related malignancies to facilitate the development of less-toxic and more efficacious therapies. ALK is increasingly recognised as a prevalent oncogene in a number of human malignancies and therefore poses a prominent clinical problem, which - requires coordinated research into its oncogenic mechanisms. ERIA now conducts a collaborative multidisciplinary research programme at the interface of biomedical and bio-mechanistic approaches, which will be an excellent environment to train the - next generation of European scientists. The 15 recruited fellows will be incorporated into international academic study groups (all partners of the ERIA network) to perform high calibre research and also will be exposed to environments from other - sectors to broaden their experience. Secondments will include technical training within individual laboratories and SMEs (TissueGnostics, Galkem, Cambridge Life Sciences, Sofigen and Varionostics) as well as large Pharma (Roche). Training through - research will be complemented with a balanced programme of transferable skills and access to local courses. The training of each fellow will be guided by a personal career development plan and supervised by a PhD committee panel. The primary goal of - the network is to train the recruited fellows by participation in an internationally competitive research programme and integrating them into an international network. Thereby providing competence in state-of-the-art research and development at the - forefront of translational science. - - 2019-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - ALKATRAS - - - H2020-MSCA-ITN-2015 - - - 675712 - - - - - FUNDACIO CENTRE DE RECERCA EN EPIDEMIOLOGIA AMBIENTAL - CREAL - FUNDACION PRIVADA INSTITUTO DE SALUD GLOBAL BARCELONA - - - EUR 170 121,60 - - - Physical Activity, Inflammation and Respiratory health: an integrative analysis of biological, behavioural and environmental determinants - - - EUR 170 121,60 - - - Spain - Spain - - - Research Organisations - Research Organisations - - The link between physical activity with respiratory health and chronic obstructive pulmonary disease (COPD) remains weak and under-investigated. The limited existing research seems to suggest that systemic inflammation could - lie in the causal pathway of this relationship, and that inflammatory-related conditions may modify this potential causal mechanism, although these hypotheses remain largely understudied. - - - 2018-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - PAIR - - - H2020-MSCA-IF-2015 - - - 704268 - - - - - FUNDACIO CENTRE DE RECERCA EN EPIDEMIOLOGIA AMBIENTAL - CREAL - FUNDACION PRIVADA INSTITUTO DE SALUD GLOBAL BARCELONA - - - EUR 170 121,60 - - - Engaging Citizens in Science: Promoting the Viability of Participatory Sensing for Monitoring Air and Environmental Quality - - - EUR 170 121,60 - - - Spain - Spain - - - Research Organisations - Research Organisations - - Participatory sensing initiatives for monitoring air and environmental quality are flourishing as a result of the citizens’ growing concern about pollution. Scientific teams and Do it Yourself communities are developing - personal sensor kits and data aggregation platforms, leveraging smartphones to gather environmental data. However, the human and social aspects that have the power to sustain these citizen science projects do not receive enough attention. - - 2017-03-31, closed project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - ESAIRE - - - H2020-MSCA-IF-2014 - - - 656439 - - - - - UNIVERSIDADE DO PORTO - KATHOLIEKE UNIVERSITEIT LEUVEN - UNIVERSITE DE STRASBOURG - CHRISTOS PAPADOPOULOS & SIA O.E. - LAZER SPORT NV - CENTER FOR TECHNOLOGY RESEARCH AND INNOVATION (CETRI) LTD - - - EUR 1 350 000 - - - Intersectoral Network for Innovation on Smart Thermal Solutions for Bicycle Helmets - - - EUR 1 350 000 - - - Portugal - Belgium - France - Greece - Belgium - Cyprus - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Bicycle helmets are a tremendously important asset against head injuries during accidents. However, their normal use is often associated with strong thermal discomfort due to the (thermally) insulating nature of the materials - used in their structures. This affects directly the willingness to wear helmets, which has direct implications in terms of the risk to which riders are exposed to. However, the capacity and expertise to improve the thermal performance of helmets - exist on academic institutions (e.g. expertise in thermal physiology, monitoring of bio-responses, active cooling) but they lack a viable supply chain to go from prototypes to finished products, ready for exploitation. On the other hand, SMEs lack - the technical skills and research facilities to perform R&D activities, to solve the mentioned problem. To solve this intersectoral problem, the SmartHELMET project will create a sustainable ecosystem of collaboration and knowledge transfer - between academic and industrial partners that will develop the next generation of bicycle helmets with smart thermal management. The project’s innovative aspects in terms of new products, processes and applications are very significant, as the new - knowledge has many potential applications in the development of other smart headgear products (e.g. motorcycle helmets, industrial protective headgear, sports related headgear, etc.) as well as smarts products in other sectors where the thermal - aspect is crucial (e.g. protective garments, sports clothing and footwear). To achieve its objectives, SmartHELMET will put together research expertise and resources from three large academic partners with market, commercialization and innovation - experience from three SMEs, to exchange knowledge through intersectoral staff secondments. The project will bridge research initiatives between the academic and industrial sectors, creating long-term cooperation between them, while raising society - awareness about its implications for citizens. - - 2019-02-28, ongoing project | - - - 2015-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Portugal - - - SmartHELMET - - - H2020-MSCA-RISE-2014 - - - 645770 - - - - - ECOLE POLYTECHNIQUE - ECOLE POLYTECHNIQUE - UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6 - - - EUR 1 165 625 - - - Statistical modelling across price and time scales: a quantitative approach to modern financial regulation - - - EUR 1 165 625 - - - France - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project aims at providing a new quantitative approach to financial regulation, notably in the context of high frequency trading. The key idea of our method is to build relevant statistical models through price and time - scales, connecting the microstructure of financial markets to the long term behavior of prices. Doing so, we will be able to understand and quantify the macroscopic consequences of regulatory measures modifying the microscopic design of the market. - Succeeding in this modelling task will require to address several intricate statistical problems. In particular new results will be needed in the fields of limit theory for semi-martingales, multifractal processes, rough stochastic differential - equations, Hawkes processes and high-dimensional statistics. Hence, through this project, we not only have the hope to provide groundbreaking tools for worldwide regulation of financial markets but, concurrently, to answer important and challenging - mathematical problems. In term of analyzing concrete regulatory measures, particular attention will be devoted to the issue of the choice of a proper tick value, that is the minimal price increment allowed on a financial market. Indeed, the tick - value is the tool which seems to be favored by most policy makers in order to regulate high frequency trading. - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - STAQAMOF - - - ERC-2015-STG - - - 679836 - - - - - EBERHARD KARLS UNIVERSITAET TUEBINGEN - - - EUR 239 860,80 - - - Interacting relativistic quantum dynamics via multi-time integral equations - - - EUR 239 860,80 - - - Germany - - - Higher or Secondary Education Establishments - - Multi-time wave functions are quantum-mechanical wave functions with N space-time arguments for N particles. They were suggested by the Nobel laureates Dirac, Tomonaga and Schwinger as a particularly natural way of achieving - manifest Lorentz invariance in the Schrödinger picture. While for a long time it was not clear how to obtain consistent interacting dynamics for multi-time wave functions, this has changed recently when a series of papers has clarified the theory of - multi-time Schrödinger equations and provided the first interacting toy models. This project aims, with the long-term goal of a rigorous multi-time formulation of quantum field theory in mind, at improving on these models by considering the - possibility of integral equations to formulate interacting dynamics for multi-time wave functions of N=2 particles. This is especially promising, as integral equations avoid a restrictive consistency condition that one faces for differential - multi-time equations. Furthermore, the typical ultraviolet divergencies of quantum field theory are avoided. - - 2019-05-31, ongoing project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Germany - - - Multi-time Integral Eqs. - - - H2020-MSCA-IF-2015 - - - 705295 - - - - - ISTITUTO NAZIONALE DI GEOFISICA E VULCANOLOGIA - INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER - HELLENIC CENTRE FOR MARINE RESEARCH - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - NATURAL ENVIRONMENT RESEARCH COUNCIL - MARINE INSTITUTE - UNIVERSITAET BREMEN - INSTITUTO PORTUGUES DO MAR E DA ATMOSFERA IP - INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU GEOLOGIE SI GEOECOLOGIE MARINA-GEOECOMAR - SLR ENVIRONMENTAL CONSULTING(IRELAND)LIMITED - ENGINEERING - INGEGNERIA INFORMATICA SPA - - - EUR 4 298 602 - - - EMSO implementation and operation: DEVelopment of instrument module - - - EUR 4 529 864,98 - - - Italy - France - Greece - Spain - United Kingdom - Ireland - Germany - Portugal - Romania - Ireland - Italy - - - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The EMSODEV general objective is to catalyse the full operations of the EMSO distributed Research Infrastructure, through the development and deployment of the EMSO Generic Instrument Module (EGIM). EGIM will provide accurate, - consistent, comparable, long-term measurements of ocean parameters, which are key to addressing urgent societal and scientific challenges (e.g. climate change and hazards). This will lead to an increased interoperability of EMSO nodes and to the - common collection of ocean essential variable time series. - - - 2018-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-3-2015 - Individual implementation and operation of ESFRI projects - - - RIA - Research and Innovation action - - - Italy - - - EMSODEV - - - H2020-INFRADEV-1-2015-1 - - - 676555 - - - - - THE BRITISH LIBRARY BOARD - MONASH UNIVERSITY - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH - DATACITE – INTERNATIONAL DATA CITATION INITIATIVE - THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL - EUROPEAN MOLECULAR BIOLOGY LABORATORY - ELSEVIER BV - ORCID EU - UNIVERSITAET BREMEN - PUBLIC LIBRARY OF SCIENCE - - - EUR 3 456 250 - - - THOR – Technical and Human Infrastructure for Open Research - - - EUR 3 458 250 - - - United Kingdom - Australia - Switzerland - Germany - United States - Germany - Netherlands - Belgium - Germany - United States - - - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Other - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Other - - Five years ago, a global infrastructure to uniquely attribute to researchers their scientific artefacts (articles, data, software…) appeared technically and socially infeasible. Since then, DataCite has minted over 3.5m unique - identifiers for data. ORCID has deployed an open solution for identification of contributors with over 850,000 registrants in less than 2 years. - - - 2017-11-30, closed project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.3."> - - - EINFRA-7-2014 - Provision of core services across e-infrastructures - - - RIA - Research and Innovation action - - - United Kingdom - - - THOR - - - H2020-EINFRA-2014-2 - - - 654039 - - - - - STICHTING CENTRUM VOOR WISKUNDE EN INFORMATICA - BANCO SANTANDER SA - VORTECH BV - ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA - UNIVERSIDADE DA CORUNA - ANALISTAS FINANCIEROS INTERNACIONALES SA - ERNST & YOUNG ACCOUNTANTS LLP - TECHNISCHE UNIVERSITEIT DELFT - NIER INGEGNERIA SPA - UNIPOL GRUPPO FINANZIARIO SPA - - - EUR 1 522 617,12 - - - Applied mathematics for risk measures in finance and insurance, in the wake of the crisis - - - EUR 1 522 617,12 - - - Netherlands - Spain - Netherlands - Italy - Spain - Spain - United Kingdom - Netherlands - Italy - Italy - - - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The EID WAKEUPCALL has been set up with the knowledge that, in the WAKE of the financial crisis, a reconsideration of fundamental assumptions that have been standard in the mathematical models for the valuation of financial - and insurance products, like CALLs is taking place. The crisis alerted to reiterate models, assumptions and computations. It is now better understood that the usual paradigm, in which financial risks can be mitigated, spread, or even hedged away - perfectly, is too simplistic for markets under stressed conditions. Lead by the Basel Committee on Banking Supervision, financial and insurance institutions are currently implementing new paradigms regarding risk management. Many of the updates in - the risk measures involve sophisticated mathematics. In this sense, the crisis has provided important feedback on appropriate directions for the required mathematical improvements. As regards to hedging and risk mitigation, which are important steps - in the risk management chain, nowadays even the hedging of basic financial instruments has become a complicated task. More sophisticated models are needed if hedging programs are to remain effective under financial stress. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-EID - Marie Skłodowska-Curie Innovative Training Networks (ITN-EID) - - - MSCA-ITN-EID - European Industrial Doctorates - - - Netherlands - - - WAKEUPCALL - - - H2020-MSCA-ITN-2014 - - - 643045 - - - - - SVERIGES LANTBRUKSUNIVERSITET - BIOBANKS AND BIOMOLECULAR RESOURCES RESEARCH INFRASTRUCTURE CONSORTIUM (BBMRI-ERIC) - KAROLINSKA INSTITUTET - UPPSALA UNIVERSITET - UNIVERSITY OF THE WESTERN CAPE - MAKERERE UNIVERSITY - STELLENBOSCH UNIVERSITY - CENTRE INTERNATIONAL DE RECHERCHE SUR LE CANCER - International Livestock Research Institute - MEDIZINISCHE UNIVERSITAT GRAZ - INSTITUTE OF HUMAN VIROLOGY NIGERIA LTDGTE - - - EUR 2 001 250 - - - Bridging Biobanking and Biomedical Research across Europe and Africa - - - EUR 2 035 250 - - - Sweden - Austria - Sweden - Sweden - South Africa - Uganda - South Africa - France - Kenya - Austria - Nigeria - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - - B3Africa - Bridging Biobanking and Biomedical Research across Europe and Africa will dramatically improve and facilitate the development of better predictive, preventive and personalized healthcare worldwide. The rapidly - evolving African biobanks are an invaluable resource: The African population has the greatest genomic diversity on the planet and represents an incredible resource of information to advance biomedical research. B3Africa aims to implement a - cooperation platform and technical informatics framework for biobank integration between Africa and Europe. The collaboration harmonizes the ethical and legal framework, biobank data representation and bioinformatics pipelines for sharing data and - knowledge among biobanks and allowing access for researchers from both continents. Main actors from the relevant initiatives including Human Heredity and Health in Africa project (H3Africa), European Biobanking and Biomolecular Resources research - infrastructure (BBMRI-ERIC) and LMIC Biobank and Cohort Network (BCNet) collaborate in B3Africa to address the following objectives: - - 2018-06-30, ongoing project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.3.2."> - - - INFRASUPP-6-2014 - International cooperation for research infrastructures - - - CSA - Coordination and support action - - - Sweden - - - B3Africa - - - H2020-INFRASUPP-2014-2 - - - 654404 - - - - - UNIVERSITY COLLEGE LONDON - - - EUR 245 185,70 - - - Displacing Deviance: Second-Generation Migrant Youth, Disciplinary Return, and Transnational Social Fields of Inclusion and Exclusion return - - - EUR 245 185,70 - - - United Kingdom - - - Higher or Secondary Education Establishments - - ‘Displacing Deviance…’ is a state-of-the-art research project into transnational family practices. It examines ‘disciplinary return’ - young second-generation migrants sent ‘home’ to their countries of heritage by their - parents as a disciplinary measure – a widespread practice which has not yet been the focus of direct research. Second-generation ties to the homeland are critical to issues of integration, yet understanding of second-generation transnationalism is - thin. Examining ‘disiplinary return’ within the Nigerian diaspora will establish new, in-depth understanding of how migrants navigate transnational structures of opportunity and constraint through their family practice. This will shed light on the - relationship between socio-economic challenges faced in ‘host’ countries, and how migrants build loyalties and identities in a transnational context. It will produce findings of relevance to policy concerns about societal challenges around - multicultural integration and minority youth in the education and criminal justice sectors. The research approach is innovative, answering calls for youth-centric, multi-sited, and intergenerational research into transnational families, thus far - mostly studied via first-generation migrant parents in single locations. Qualitative research with migrant parents and youth, and participatory research with migrant youth, will be undertaken in the USA, Nigeria and the UK. Supervision by a world - expert, Dr Coe at Rutgers, in the outgoing phase will provide a unique training opportunity for the researcher and excellent means to build networks. Expertise gained will be transferred back into Europe in the incoming phase by working with Dr - Dwyer, co-director of the Migration Research Unit (Geography Department) at UCL, a hub for migration research with Europe-wide networks. This will maximise output which advance theoretical debates around migration and transnationalism, speak to - policy debates, and capture public audiences. - - 2020-09-30, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - 2GENRETURN - - - H2020-MSCA-IF-2016 - - - 750495 - - - - - PANEPISTIMIO THESSALIAS - UNIVERSIDADE DO PORTO - IMEDICA SA - CENTER FOR TECHNOLOGY RESEARCH AND INNOVATION (CETRI) LTD - - - EUR 828 000 - - - Intersectoral collaboration for innovation in non-invasive techniques to estimate human brown adipose tissue activity - - - EUR 828 000 - - - Greece - Portugal - Romania - Cyprus - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Non-invasive, inexpensive, and accurate assessment of adipose tissue (BAT) activity is crucial in the fight against metabolic pandemics such as obesity, and in various industries (e.g., foods, pharmaceuticals). However, the - only technique available to measure the activity of this tissue is PET/CT imaging of the glucosetracer 18F-fluorodeoxyglucose , a highly invasive technique that is harmful for human health, expensive, and requires extensive equipment and facilities. - The development and validation of non-invasive and practical techniques to accurately estimate human BAT activity requires the creation of new technology and the advancement of the current state of the art. Companies (particularly SMEs) do not have - the technical capabilities to conduct R&D activities at the level of excellence required for such development. Academic institutions have the capacity to conduct the necessary R&D but they lack the expertise to develop the prototype post - project. To solve this intersectoral problem, the ICI-THROUGH project will create a sustainable innovation platform of intersectoral collaboration between two academic (UOT and UOP) and two industrial (IMED and CETRI) European participants to - exchange knowledge on the development of non-invasive techniques to estimate human BAT activity. This will be achieved via a series of clear and measurable research and innovation objectives that will be realized via staff exchanges of experienced - and early-stage researchers divided into: networking, research and training, workshop, innovation, dissemination, and public engagement activities. The ICI-THROUGH project is effectively aligned with the scope of the RISE call and its success is in - the interest of all participants. Also, exploitation of the obtained tangible outcomes (e.g., prototype) will ensure the partnership’s sustainability post project. Thus, the ICI-THROUGH project has high potential to become a self-sustaining - innovation incubator between the four participants. - - 2018-11-30, ongoing project - - - 2014-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Greece - - - ICI-THROUGH - - - H2020-MSCA-RISE-2014 - - - 645710 - - - - - UNIVERSITE DE BOURGOGNE - - - EUR 185 076 - - - Stalling the Replication Fork via the Impedimental Stabilization of Higher-order DNAs - - - EUR 185 076 - - - France - - - Higher or Secondary Education Establishments - - "Cancer is a generic term for a group of diseases characterized by the uncontrolled growth and spread of cells with abnormal proliferating activity. Most of the anticancer drugs currently used in the clinic trigger - irreversible DNA damages and thus, promote replicative stress. As an alternative of irreversible DNA strand breaks, the non-covalent small-molecule stabilization of unusual, non-B DNA structures has emerged as a promising way to create DNA damages. - One of such non B-DNA structures is a three-way DNA junction that might fold both upstream and downstream of the replication fork. The stabilization of three-way junctions by small molecules therefore opens a promising way to induce replicative - stress in a highly cancer-specific manner. The main goal of the project ""STARFISH DNA"" (for ""Stalling the Replication Fork via the Impedimental Stabilization of Higher-order DNAs"") is to identify a new series of compounds capable of creating DNA - damages through three-way junction stabilization and to use them either as standalone therapeutic agent to fight against cancers or in combination with established drugs that disrupt cancer signaling pathways in a synergistic manner." - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - STARFISH DNA - - - H2020-MSCA-IF-2016 - - - 750368 - - - - - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - - - EUR 175 419,60 - - - Increasing the robustness and neural integration of bidirectional prostheses for rehabilitation withrobust and real time Independent Component Analysis - - - EUR 175 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - Hand loss is a highly disabling event that markedly affects the quality of life. To achieve a close to natural replacement for the lost hand, the user should be provided with the rich sensations that are naturally perceive - when grasping or manipulating an object. Ideal bidirectional hand prostheses should involve both a reliable decoding of the user’s intentions and the delivery of nearly “natural” sensory feedback through remnant afferent pathways, simultaneously and - in real time. As such, much effort in the last decade has been directed towards the achievement of both the robust performance necessary for natural prosthesis control and the sensory feedback integration. Despite this however, researchers have - struggled so far to translate their findings to clinical and commercial applications, as it is necessary first to develop robust multifunctional myoelectric control algorithms and to characterize the neurophysiological responses elicited by - artificial sensory feedback. The first aim of BIREHAB is to characterize the cortical activity evoked by neuromorphic electrical stimulations of the median and ulnar nerve in amputees and compare it with healthy subjects’s undergoing the same - protocl. The second aim is to develop a new blind source separation algorithm (Independent Component Analysis) for the robust extraction of muscle synergies and Motor Unit Action Potentials from high density surface electromyogram. ICA will also be - useful to overcome the current issues that impair the efficacy of myoelectric prostheses control, such as electrodes cross talk and volume conduction. The implementation of BIREHAB has the potential to aid in the personalization of post-stroke - rehabilitation protocols, and to improve the long term efficacy, quality and neural integration of hand prostheses. These results may enable, in the near future, near-natural replacement of missing hands and will help devise new upper limb - rehabilitation strategies. - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - BIREHAB - - - H2020-MSCA-IF-2016 - - - 750947 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 158 121,60 - - - GaTHeR, Gender and Transfer of Knowledge in Hunter Gatherer Research - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - This project analyses feminist knowledge transfer in mainstream Science. Following the European Research Area key priority of strengthening the Gender dimension in research programs, the goal of this research is building a - methodology to better understand the relations between Knowledge Production, Gendered Organisations and Methodological Challenges through a multidisciplinary case-study; hunter-gatherer (HG) research. - - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - GaTHeR - - - H2020-MSCA-IF-2016 - - - 750640 - - - - - THE UNIVERSITY OF BIRMINGHAM - ISTITUTO NAZIONALE DI RICERCA METROLOGICA - HEINRICH-HEINE-UNIVERSITAET DUESSELDORF - GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER - PHYSIKALISCH-TECHNISCHE BUNDESANSTALT - NPL MANAGEMENT LIMITED - JRC -JOINT RESEARCH CENTRE- EUROPEAN COMMISSION - UNIVERSITAET ULM - THE UNIVERSITY OF NOTTINGHAM - TELEDYNE E2V (UK) LIMITED - - - EUR 945 000 - - - Quantum sensors - from the lab to the field - - - EUR 945 000 - - - United Kingdom - Italy - Germany - Germany - Germany - United Kingdom - Belgium - Germany - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Research Organisations - Paolo Antonio Mastroeni - Tel.: +39-011-3919541 - Fax: +39-011-346384 - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Q-SENSE will promote international and inter-sector collaboration for the advancement of science and the development of innovation in the area of cold atom quantum sensors. In particular it fosters a shared culture of research - and innovation that turns the Nobel-prize winning ideas of cold atom research and precision measurement (Nobel prizes 1997 and 2005) into innovative products. In particular, we bring together a synergetic network of the world leaders in optical - clocks and atom interferometers with technology translators and end user applicants to promote space and terrestrial applications of optical clocks and cold atom gravity sensors with an additional eye on implications on policies via the JRC. Our - research and innovation programme will deliver knowledge exchange around a technology demonstrator for a space optical clock, development plans for atom interferometer satellite missions, an open source toolbox for simulations of atom interferometer - performance in real-world applications and outreach to over 70 companies and the public raising awareness of the potential of optical clocks and cold atom gravimeters for economic and societal benefits, such as in global water monitoring, - humanitarian de-mining, satellite navigation and broadband communication. Q-SENSE will enhance the skills of research- and innovation-related human resources in our partner organisations to work seamlessly across sectors and provide new career - perspectives in the emerging area of commercial quantum technologies. - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - United Kingdom - - - Q-Sense - - - H2020-MSCA-RISE-2015 - - - 691156 - - - - - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - - - EUR 183 454,80 - - - From CO2, Water and Sunlight to Valuable Solar Fuels: Tracking Reaction Intermediates in Solar Fuel Generation with Ultrafast Spectroscopy for More Efficient Catalysis - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Fundamental understanding of the catalytic chemistry and underlying mechanisms in carbon dioxide (CO2) reduction is an urgent need for efficient solar energy conversion from CO2, water and sunlight to valuable carbon-neutral - fuels that urgently need to replace our fossil fuel-based economy of today. This proposal focuses on unraveling the reaction mechanisms of the reduction of CO2 in aqueous photoelectrochemical (PEC) systems in order to allow innovative development of - more efficient chemistry for the production of solar fuels based on the understanding of the underlying mechanisms. - - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - CO2 Intermediates - - - H2020-MSCA-IF-2016 - - - 749231 - - - - - THE SAINSBURY LABORATORY - - - EUR 195 454,80 - - - Dynamic interplay between phosphorylation and ubiquitination during plant receptor kinase-mediated immunity - - - EUR 195 454,80 - - - United Kingdom - - - Research Organisations - - The first layer of plant immunity is mediated by the recognition of conserved microbial features known as pathogen-associated molecular patterns (PAMPs) by plasma membrane-localized pattern recognition receptors (PRRs). An - immediate downstream substrate of activated PRR complexes is the cytoplasmic kinase BIK1, which is a positive regulator of PAMP-triggered immunity (PTI). The objective of this proposal is to uncover how BIK1 regulates plant immune signalling via the - characterization of its substrates in PTI. The host laboratory has recently identified a potential BIK1 phosphorylation motif, which is present in 22 Arabidopsis proteins that are rapidly phosphorylated upon PAMP treatment. Eight of these proteins - have been confirmed as true BIK1 phosphorylation substrates and include several proteins involved in protein ubiquitination/deubiquitination, including an E3 ubiquitin ligase and two ubiquitin specific proteases (USPs), which will be the focus of - this study. Preliminary data indicate that the E3 ubiquitin ligase is a positive regulator of PTI. Here, I will further characterize the role of this E3 ubiquitin ligase in PTI by characterising the role of its phosphorylation by BIK1, and - identifying its substrates and their role in PTI using genetic and biochemical approaches. A similar approach will be used to decipher the role of the two USPs in PTI. The project will directly benefit from my previous experience in working with - deubiquitinating enzymes during plant development, which will provide all the necessary technical and theoretical knowledge to ensure the project’s success. This exciting project will allow me resuming my career in science, thus corresponding to the - objectives of the People Work Programme. At the end of the project, we will have a better understanding on how activated PRR complexes regulate downstream immune signalling, which is a very important question in innate immunity, in both plants and - mammals. - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - United Kingdom - - - PHOSPH-UBIQ-IMMUN - - - H2020-MSCA-IF-2016 - - - 753641 - - - - - UNIVERSITAT AUTONOMA DE BARCELONA - - - EUR 158 121,60 - - - Social Vulnerability and its Intersections: The role of gender in a comparative perspective - - - EUR 158 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - VINE seeks to disentangle the multidimensionality of the risk of social exclusion, focusing on vulnerable populations; specifically, those individuals who are in a fragile condition with regard to integration into the domains - of well-being (family, labour market, welfare state). Using EU-SILC microdata, the project analyses the interactions between social vulnerability and different individual characteristics that might magnify it. Secondly, the project intends to study - how, and in what ways, these individual characteristics combine to determine economic insecurity at household level. The main contribution of this project is proposing an analysis of how the institutional context as well as individual characteristics - affects individual risk of living in vulnerable households, from a comparative and multidimensional perspective. By comparing six European countries, as representatives of different institutional environments, the VINE project aims to deliver a - better understanding of the causes and mechanisms that determine both men and women’s exposure to social vulnerability. The innovation herein is the assumption that gender is the main analytical dimension in interactions, when theorised according to - the intersectional perspective. With a multi-dimensional explorative analysis, and multinomial logistic regression, the analysis will lead to the development of a synthetic indicator of economic insecurity at the household level, permitting - assessment of its interactions with specific individual vulnerability profiles. The final aim is to disentangle factors informing individual’s exposure to different degrees of social vulnerability, analysing their consequences and household’s - economic insecurity, and possible influences from the institutional context. Thanks to this project, the ER will fill her gap in quantitative research analysis and she will be able to empower her professional profile compete for tenure-track position - in the international academic labour market. - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - VINe - - - H2020-MSCA-IF-2016 - - - 747433 - - - - - AARHUS UNIVERSITET - - - EUR 200 194,80 - - - Impacts of Greenland Ice Sheet melt on primary productivity and carbon cycling in Greenland coastal ecosystems - - - EUR 200 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - Due to recent anthropogenic climate warming, the Greenland Ice Sheet (GrIS) is melting at accelerating rates, increasing the freshwater content of the Arctic Ocean. Freshwater run-off from the GrIS influences circulation - patterns and stratification of the water column and also introduces large fluxes of allochthonous organic and inorganic matter into the Greenland coastal environment, both of which have the potential to influence microbial carbon cycling. Changing - patterns of circulation and stratification have the potential to effect water column mixing and thus nutrient supply to primary producers, while introduction of particles and suspended sediments can limit light availability to primary producers and - provide increased surface area for bacterial activity. Recent studies also documented that GrIS melt water contains significant amounts of bioavailable organic carbon and nutrients, which could provide subsidies to the microbial community, but the - impact is unknown. At present, studies have only quantified the effects of GrIS melt water on the physical and chemical environment of Greenland fjords, no studies have addressed the physicochemical effects of melt water and its allochthonous - constituents on ecosystem carbon cycling, making it difficult to estimate how increased melting is altering the productivity regimes in coastal marine ecosystem around Greenland. Primary production is the base of the marine food web and supports - commercial and sustenance fisheries along the Greenland coast. Melting of the GrIS is expected to intensify in the future. Thus, this project proposes a timely effort to determine the impact of GrIS melt water on productivity and carbon cycling in - the Greenland coastal ecosystem, the results of which can be used by climate scientist and fisheries managers to predict the future productivity of an locally and globally important ecosystem. - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - GrIS-Melt - - - H2020-MSCA-IF-2016 - - - 752325 - - - - - UPPSALA UNIVERSITET - UPPSALA UNIVERSITET - - - EUR 2 000 000 - - - Spore killer genomics: elucidating causes and consequences of a fungal meiotic drive element - - - EUR 2 000 000 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The traditional view of the genome is that of a highly coordinated network that has evolved to produce a successful individual. However, the alternative view of the genome as containing intrinsically conflicting parts that - coevolve antagonistically, has recently emerged. Today, it is widely accepted that conflicts caused by selfish genetic elements is a driving force for evolutionary innovation, and hence, is of fundamental importance for all aspects of evolution. - Nevertheless, empirical data on the topic is largely lacking. Here, I introduce the fungus Neurospora as a novel study system of the evolutionary significance of meiotic drive. In this sexual eukaryote model system, the meiotic drive element Spore - killer is found. The cytological properties and natural distribution of Spore killing in Neurospora has been investigated for several decades, and preliminary data suggests that it is an important driver of both genome evolution and of higher-order - evolutionary processes. The existing knowledge and resources of this system provide a foundation for the proposed research program, in which I plan to build a tool-kit of genomic and experimental resources to I) identify and characterize the gene(s) - encoding Spore killer elements, II) assess the strength of Spore killer as a meiotic drive, III) unravel the evolutionary history of the Spore killer complex in Neurospora, IV) investigate the association between Spore killer and genome evolution, - and V) analyze the role of Spore killer as a driver of speciation and mating system transitions. This research program will manifest the Spore killer as a primary and pioneering model for the study of meiotic drive, and profoundly impact our - understanding of segregation distorters as drivers of eukaryote genome evolution. Furthermore, insights emerging from the project presented are conceptually important for basic evolutionary biology, in the study of natural selection acting at - multitudinal levels in a biological hierarchy. - - 2020-04-30, ongoing project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Sweden - - - SpoKiGen - - - ERC-2014-CoG - - - 648143 - - - - - ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA - ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA - - - EUR 1 993 811 - - - The earliest migration of Homo sapiens in Southern Europe: understanding the biocultural processes that define our uniqueness - - - EUR 1 993 811 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Anatomically modern humans (AMHs) radiated out of Africa into the rest of the world around 60,000-50,000 years ago. While various evidence suggests arrivals of AMHs in Asia and Australia ca. 45,000 calendar years before - present (cal BP), the timing and pattern of the biological and cultural shifts that occurred in Europe around 50,000 to 35,000 cal BP, are hotly debated and are considered to be among the most important questions in paleoanthropology. This period - documents 1) the demise of the autochthons Neandertals and their replacement by AMHs as well as 2) dramatic changes in human behaviour and the appearance of various technocomplexes that replaced pre-existing Mousterian cultures. Debate revolves - around the question of whether modern behaviour was independently achieved by Neandertals or is directly related to the arrival of AMH. In this context Italy plays a pivotal role due to its geographic position and ecological variability, and key - archaeological sites with transitional and early Upper Paleolithic cultures. - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Italy - - - SUCCESS - - - ERC-2016-COG - - - 724046 - - - - - MEDIZINISCHE UNIVERSITAT GRAZ - - - EUR 218 176,20 - - - Image-based High-resolution In-silico Modeling of Total Cardiac Function - - - EUR 218 176,20 - - - Austria - - - Higher or Secondary Education Establishments - - Advances in medical imaging have enabled unprecedented ability to image cardiac anatomy and function. So far these technologies have had relatively modest clinical impact as the analysis of such rich multi-modal datasets has - proven challenging. In silico models hold vast potential to better harness such datasets by enabling their integration into quantitative frameworks that can aid in gaining better mechanistic insight into cardiac function in health and disease, and - thus paving the way towards optimal therapeutic strategies. - - 2019-08-31, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Austria - - - InsiliCardio - - - H2020-MSCA-IF-2016 - - - 750835 - - - - - PHILIPS ELECTRONICS NEDERLAND B.V. - UNIVERSITAETSKLINIKUM AACHEN - - - EUR 766 122,84 - - - Real time therapy planning for Thermal based therapy modalities in oncology care. - - - EUR 766 122,84 - - - Netherlands - Germany - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - AdapTT will unlock the potential for development of a real time adaptive therapy planning tool for thermal treatment in prostate oncology. Highly specialized and cost effective state-of-the-art scientific solutions can only be - developed when complimentary partners of different sectors work synergistically. The intersectoral nature of the European Industrial Doctorates (EID) framework, between industry and academia, is a key requirement for success of the proposed PhD - projects. Specific application knowledge on clinical software platforms development, imaging systems and therapy modalities of the industrial partner, has to be combined with fundamental biophysical knowledge and clinical need insights of the - clinical academic partner. This combination of European based expertise is unique and being able to be exposed to these different research climates will strongly enhance the employability and career prospects of the early stage researchers (ESR’s), - participating in the program. - - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-EID - Marie Skłodowska-Curie Innovative Training Networks (ITN-EID) - - - MSCA-ITN-EID - European Industrial Doctorates - - - Netherlands - - - AdapTT - - - H2020-MSCA-ITN-2014 - - - 642445 - - - - - CARL VON OSSIETZKY UNIVERSITAET OLDENBURG - - - EUR 159 460,80 - - - Dark Ocean Cosmeceuticals -DOC-: The Cosmetical and Pharmaceutical Potential of Marine Dissolved Organic Matter - - - EUR 159 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - An ageing population as well as chronic and infectious diseases, pandemic threats and antimicrobial resistance are currently on the rise. As a consequence, increasing attention is paid to the development of novel drugs, - treatments and personal care products. In this context, blue biotechnology offers an opportunity to explore the potential of the marine microbial world to produce biological active metabolites, which may support health and wellbeing. The general goal - of this proposal is the extraction and identification of biologically active substances in one of the largest reservoirs of organic material on Earth: the recalcitrant marine dissolved organic matter (RDOM) pool. This pool is an unexplored potential - source of bioactive substances. For this purpose, the RDOM will be extracted from (1) one of the oldest water masses of the global ocean located at intermediate depths of the North Pacific and (2) the reworked DOM of marine sediments porewater in the - North Sea. A comparative screen will be performed with the more recent surface oceanic water of the North Pacific. The antioxidant, immunostimulant and antitumoral potential of these DOM samples will be explored to evaluate possible cosmetical and - pharmaceutical suitability. The DOM molecular diversity and features identified by mass spectrometry and nuclear magnetic resonance will be correlated with the different modes of bioactivity. This proposal will enable Dr. Catalá to broaden her - expertise on molecular characterization of the DOM pool, to learn new methodologies of bioactive substances identification as well as to meet future challenges on marine natural product research, endorsed by the H2020 Societal Challenges of 'Health, - Demographic Change and Wellbeing' and 'Marine Research and the Bioeconomy'. This combination of expertise is unique, and thus will be a milestone in Dr. Catalá career towards an independent scientist of high international visibility. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - DOC - - - H2020-MSCA-IF-2016 - - - 749586 - - - - - PAUL SCHERRER INSTITUT - PAUL SCHERRER INSTITUT - - - EUR 1 999 926 - - - Hyperfine splittings in muonic atoms and laser technology - - - EUR 1 999 926 - - - Switzerland - Switzerland - - - Research Organisations - Research Organisations - - The proton radius extracted from the measurements of the 2S-2P energy splitting in muonic hydrogen - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Switzerland - - - HyperMu - - - ERC-2016-COG - - - 725039 - - - - - ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA - ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA - UNIVERSITAET HAMBURG - - - EUR 1 465 943 - - - The Magnetised Cosmic Web - - - EUR 1 465 943 - - - Italy - Italy - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - On large scales cosmic matter is distributed in a web consistent of clusters, filaments, walls and voids. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Italy - - - MAGCOW - - - ERC-2016-STG - - - 714196 - - - - - FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA - FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA - QBROBOTICS SRL - - - EUR 149 787 - - - A Soft Synergy-based Hand Prosthesis with Hybrid Control - - - EUR 149 787 - - - Italy - Italy - Italy - - - Research Organisations - Chiara Andreoli - Tel.: +3901071781854 - Fax: +39 010 7170817 - Research Organisations - Chiara Andreoli - Tel.: +3901071781854 - Fax: +39 010 7170817 - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - In the project “SoftHands” we have achieved not only a more thorough understanding of the organization and control of hands, but also a principled approach to taming the complexity of hand design. The original concept of “soft - synergies” has underpinned the realization of radically new artificial hands: “SoftHands” have been demonstrated to be more adaptive and capable than most artificial hands, yet are simpler to control and more robust. One application of these ideas - and technologies which stands out for potential impact and social relevance, although not originally foreseen in the ERC AG plan, is the realization of upper limb pros-theses. The objective to realize a prosthetic hand that is anthropomorphic, - aesthetically pleasing, and enables an amputee to perform most activities of daily living as well as advanced prostheses, while being robust, intuitive, and economic as basic body-powered split-hook prostheses requires a much longer and larger - re-search and development effort than an ERC POC can support. In this proposal we study the feasibility of applying the SoftHand technology to address one particular, but very important, objective, i.e. work-oriented prostheses. The specific - requirements of these applications are high grip power, grasp versatility, resilience, resistance to water, dust, and temperature, durability, power autonomy and low cost – while factors such as aesthetics or silent operation are less dominant. Of - particular relevance is the control interface with the patient. Virtually all work-oriented prostheses are operated via a body-powered cable, which is very intuitive to use and does not need batteries, motors, and sensors. On the other hand, advanced - multi-fingered prostheses have sophisticated myoelectric control affording versatility and dexterity. In this project, we will engineer and experiment a novel hybrid control for a SoftHand prosthe-sis, whereby a traditional cable harness commands the - advanced mechatronic system of the SoftHand. - - 2018-03-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Italy - - - SoftHand Pro-H - - - ERC-2016-PoC - - - 727536 - - - - - UNIVERSITETET I BERGEN - UNIVERSITETET I BERGEN - - - EUR 1 997 918 - - - Discretion and the child´s best interests in child protection - - - EUR 1 997 918 - - - Norway - Norway - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - DISCRETION aims to unlock the black box of discretionary decision-making in child protection cases by a comparative-empirical study of how discretionary decisions are made and justified in the best interests of the child. - There are huge research gaps in this important area of the welfare state, with a great deal of uncertainty concerning how, when and why discretionary decisions about the child´s best interests are different between decision-makers within and between - child protection systems. - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Norway - - - DISCRETION - - - ERC-2016-COG - - - 724460 - - - - - UNIVERSITY COLLEGE LONDON - UNIVERSITY COLLEGE LONDON - - - EUR 2 159 035 - - - Evolving Program Improvement Collaborators - - - EUR 2 159 035 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - EPIC will automatically construct Evolutionary Program Improvement Collaborators (called Epi-Collaborators) that suggest code changes that improve software according to multiple functional and non-functional objectives. The - Epi-Collaborator suggestions will include transplantation of code from a donor system to a host, grafting of entirely new features `grown' (evolved) by the Epi-Collaborator, and identification and optimisation of tuneable `deep' parameters (that were - previously unexposed and therefore unexploited). - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - EPIC - - - ERC-2016-ADG - - - 741278 - - - - - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - - - EUR 2 499 994 - - - INTEGRATION AND PROPAGATION OF IMMUNOLOGICAL SIGNALS DURING CANCER AND INFECTION - - - EUR 2 499 994 - - - France - France - - - Research Organisations - Research Organisations - - The immune system uses both short- and long-range communication mechanisms to mount the coordinated and sophisticated cellular responses required to control microbial infections or fight tumors. Yet, our understanding of how - immunological signals are integrated and propagated by individual cells in complex tissue microenvironments remains largely limited. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - France - - - ENLIGHTEN - - - ERC-2016-ADG - - - 741167 - - - - - CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL - KATHOLIEKE UNIVERSITEIT LEUVEN - UNIVERSITY OF NEWCASTLE UPON TYNE - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - UNIVERSIDADE DO PORTO - STICHTING VU - ACADEMISCH ZIEKENHUIS GRONINGEN - Centre Hospitalier Regional et Universitaire de Lille - MOTEK MEDICAL B.V. - GAIT UP SA - HASOMED HARD-UND SOFTWARE FUER MEDIZIN GESELLSCHAFT MBH - PATIENTS KNOW BEST LIMITED - - - EUR 3 059 313,21 - - - Industrial Academic Initial Training Network towards specific diagnosis and treatment of age-related gait and balance deficits - - - EUR 3 059 313,21 - - - Germany - Belgium - United Kingdom - Germany - Portugal - Netherlands - Netherlands - France - Netherlands - Switzerland - Germany - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Balance and gait deficits are ubiquitous among the older population, and lead to enormous personal, occupational and health care burden. Emerging pharmacological and non-pharmacological interventions to date have only small to - moderate effects on these deficits. This is likely due to remaining fundamental questions on underlying mechanisms and treatment. The present project Keep Control consists of a rare EU-wide combination of experts from clinical, biomechanic and - neuroscience research, along with experts from the industry, who all aim at gaining a better understanding and treatment of balance and gait deficits in older adults. We aim to scrutinize aspects such as: (1) comparability of balance and gait - assessment in the clinic and the home environment, (2) gait and balance deficits as prodromal markers of neurodegeneration, and as markers to differentiate between Parkinsonian syndromes, (3) association between freezing of gait and balance, and (iv) - gait and balance deficits in patients with sarcopenia. Tools such as sophisticated lab-based gait and balance assessment devices, perturbation treadmill, wearable devices, electrophysiology and blood and tissue investigations will be implemented. We - will further employ promising therapeutic strategies for specific gait and balance deficits in older adults, including both pharmacologic and non-pharmacologic strategies. An entire work package will be dedicated to a novel harmonization and - integration approach across the whole network: It will (i) harmonize assessment protocols based on the WHO definition of health and disability, to pave the way for an exhaustive meta-analysis of all data collected, and (ii) foster the active - involvement of all study participants by implementation of a participant-controlled medical record. In summary, Keep control will cover the entire range of expertise necessary and utilize cutting edge technology to educate fellows in the area of gait - and balance deficits in older adults. - - 2021-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - Keep Control - - - H2020-MSCA-ITN-2016 - - - 721577 - - - - - TECHNISCHE UNIVERSITAET WIEN - TECHNISCHE UNIVERSITAET WIEN - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 460 826 - - - Towards chemical accuracy in computational materials science - - - EUR 1 460 826 - - - Austria - Austria - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - This project aims at the development of a novel toolbox of ab-initio methods that approximate the true many-electron wavefunction using systematically improvable perturbation and coupled-cluster theories. The demand and - prospects for these methods are excellent given that the highly-accurate coupled-cluster theories can predict atomization- and reaction energies in a wide range of solids and molecules with chemical accuracy (≈43 meV). However, the computational cost - involved inhibits their widespread use in the field of materials science so far. A multitude of suggested developments in the present proposal hold the promise to reduce the computational cost beyond what is currently considered possible by the - community. These include explicit correlation methods that augment the conventional wavefunction expansion with terms that depend on the electron pair correlation factors. In contrast to the widely-used homogeneous correlation factors, this proposal - aims at the investigation of inhomogeneous correlation factors that can also capture van der Waals interactions. Furthermore this proposal seeks to employ a recently developed combination of atom-centered basis functions and plane wave basis sets, - maximizing the compactness in the wavefunction expansion. The combination of these ideas bears the potential to reduce the computational cost of coupled-cluster calculations in solids by three orders of magnitude, leading to a breakthrough in the - field of highly-accurate ab-initio simulations. As such the study of challenging solid state physics and chemistry problems forms an important part of this proposal. We seek to investigate molecular adsorption and reactions in zeolites and on - surfaces, pressure-driven solid-solid phase transitions of two dimensional layered materials and defects in solids. These problems are paradigmatic for van der Waals interactions and strong correlation, and methods that describe their electronic - structure accurately are highly sought after. - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Austria - - - CC4SOL - - - ERC-2016-STG - - - 715594 - - - - - JOHANN HEINRICH VON THUENEN-INSTITUT, BUNDESFORSCHUNGSINSTITUT FUER LAENDLICHE RAEUME, WALD UND FISCHEREI - FONDAZIONE CENTRO EURO-MEDITERRANEO SUI CAMBIAMENTI CLIMATICI - WEST AFRICAN SCIENCE SERVICES CENTRE ON CLIMATE CHANGE AND ADAPTED LAND USE - International Livestock Research Institute - INTEGRATED CARBON OBSERVATION SYSTEM EUROPEAN RESEARCH INFRASTRUCTURE CONSORTIUM - UNIVERSITY OF THE WITWATERSRAND JOHANNESBURG - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - SOUTHERN AFRICAN SCIENCE SERVICE CENTRE FOR CLIMATE CHANGE AND ADAPTIVE LAND MANAGEMENT - NATIONAL RESEARCH FOUNDATION - HELMHOLTZ ZENTRUM FUR OZEANFORSCHUNG KIEL - LEIBNIZ INSTITUT FUER TROPOSPHAERENFORSCHUNG e.V. - UNIVERSITETET I BERGEN - UNI RESEARCH AS - USTAV VYZKUMU GLOBALNI ZMENY AV CR VVI - LUNDS UNIVERSITET - INSTITUTO NACIONAL DE DESENVOLVIMENTO DAS PESCAS - - - EUR 1 999 890 - - - Supporting EU-African Cooperation on Research Infrastructures for Food Security and Greenhouse Gas Observations - - - EUR 1 999 890 - - - Germany - Italy - Ghana - Kenya - Finland - South Africa - Ireland - Namibia - South Africa - Germany - Germany - Norway - Norway - Czech Republic - Sweden - Cape Verde - - - Research Organisations - Research Organisations - Other - Research Organisations - Other - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - - African societies face growing global change risks, with rapidly changing patterns of human settlements and intensity of use of ecosystem services. At the same time, climate variability and climate change trends are - intensifying stress on the ecosystems that ensure environmental security, both locally (e.g. ecosystem services), regionally (e.g. sustainable development options) and internationally (e.g. carbon sequestration). Approaches that can address this - challenge in an integrated and multidisciplinary way are urgently needed in many places in Africa where there is a close relationship between societal well-being and environmental condition, relating particularly to biomass for energy and food - production, and hydrological considerations such as water yields. - - - 2020-02-29, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.3.1., H2020-EU.1.4.3.2."> - - - INFRASUPP-01-2016 - Policy and international cooperation measures for research infrastructures - - - CSA - Coordination and support action - - - Germany - - - SEACRIFOG - - - H2020-INFRASUPP-2016-1 - - - 730995 - - - - - UNIVERSITAT ZURICH - - - EUR 187 419,60 - - - Embodied Cognitive Neuromorphic Technology - - - EUR 187 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - Biological neuronal networks allow humans and animals to build representations of objects, complex scenes, and temporal sequences and to use these representations to plan and execute goal-directed actions, learn new skills, - and constantly adapt to changing situations. Neuronal systems have evolved to be extremely powerful in perceiving and acting in complex and dynamic real-world environments. The field of neuromorphic engineering is realising neuronal computation in a - new generation of hardware systems, aiming to enable computation with high efficiency and low energy cost, comparable to biological neuronal networks. In order to use this hardware to implement systems that can solve perceptual, motor, and cognitive - tasks, cognitive architectures have to be developed, which integrate elementary cognitive processes in a coherent computational framework. The ECogNeT project aims to develop such a computational framework by realising neural-dynamic models of - embodied cognition in neuromorphic hardware. In particular, the computational and conceptual framework of Dynamic Neural Fields will be used to create cognitive computational primitives in neuromorphic hardware, which will organise the hardware - neurons in attractor-networks, capable to generate discrete, cognitive representations from sensory inputs. The developed neuromorphic cognitive architecture will be integrated with sensors and motors of a robotic agent and its capability to - represent environmental situations and temporal sequences of events will be validated in benchmark scenarios, exploiting the potential of this new technology in development of novel, low-power, fast, and smart devices capable to work in real-world - settings in order to advance future prosthetic systems, smart environments, and assistive robots. - - 2018-03-31, Grant Agreement terminated | - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - ECogNeT - - - H2020-MSCA-IF-2015 - - - 707373 - - - - - HELSINGIN YLIOPISTO - UNIVERSITEIT GENT - POLITECHNIKA WARSZAWSKA - VOXDALE BVBA - UNIVERSITEIT ANTWERPEN - Academisch Medisch Centrum bij de Universiteit van Amsterdam - APTUIT (VERONA) SRL - UNIVERSIDADE DO PORTO - - - EUR 2 265 900,12 - - - Multidisciplinary European training network for development of personalized anti-infective medical devices combining printing technologies and antimicrobial functionality - - - EUR 2 265 900,12 - - - Finland - Belgium - Poland - Belgium - Belgium - Netherlands - Italy - Portugal - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - According to ECDC, over 4 million healthcare-associated infections in the EU cause 37,000 deaths and cost EUR 7 billion/year. Half of them are related to medical devices (i.e., catheters, implants) and 80% of these are related - to bacterial biofilms. A recent EC report highlighted the medical device sector’s role in driving EU economic growth, employing 500k people in 25k companies (80% are SMEs) with annual sales of EUR 85 billion. The strategy to prevent medical - device-infections is alteration of the device’s surface with antimicrobials. However, current antimicrobial surfaces don’t control bacterial growth in tissue surrounding implants, and only Sterilex® has received regulatory approval in the US as - anti-biofilm agent. Participants in this proposal have earlier demonstrated a dramatic in vitro inhibition of biofilm formation by 3D-printing surfaces with antibiotics incorporated into the carrier polymers. This discovery opens new possibilities - for printed medical devices that better resist biofilms. Our objective is to set-up a new European education platform to guide and inspire young researchers in the intersectoral exploration of innovative routes to counteract microbial biofilms by - fabricating anti-infective, tailored, 3D-printed medical devices. Current opportunities for young researchers to receive an structured, inter-sectoral and up-to-date education on personalized medicine and medical devices are marginal, and to our - knowledge PRINT-AID is the first ETN set up for this purpose. State-of-the-art printing technologies will be combined with in vitro and in vivo biofilm models and novel tools for data integration/standardization. Doctoral training will be performed - within a high-quality network of 12 participants (5 industrial) from the EU and US. It will include online and face-to-face courses taught by researchers with academic and industrial expertise in biofilms, 3D-printing research, antimicrobials, - material science, and drug development. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Finland - - - PRINT-AID - - - H2020-MSCA-ITN-2016 - - - 722467 - - - - - KATHOLIEKE UNIVERSITEIT LEUVEN - - - EUR 172 800 - - - Public Administration and Technology - - - EUR 172 800 - - - Belgium - - - Higher or Secondary Education Establishments - - Digital technologies are in the centre of the ongoing industrial revolution that is bound to change not only markets, but also societies and governments. Central to these developments is the evolution of public sector - technological capacities, that is, an ability of public organizations to explore, develop and/or adapt new technological solutions in public service design, delivery and evaluation. One of the central questions that has so far fallen in between - different research strands is how technology affects the evolution of work organization and administrative capacities in public sector. In the context of increasing dependence on technological developments, and thus, related opportunities as well as - uncertainties and risks, the conventional public administration accounts fall short in fully grasping the influence of technology on public sector change. The research objectives of the project are to: a) develop a coherent and novel conceptual - framework on public sector technological capacities and provide novel and empirically grounded explanations on the co-evolutionary development mechanisms of public organizations and technology through comparative cross-country analysis. In order to - map and understand different co-evolutionary patterns, the project will use a comparative approach by studying two different fields (with high and low/moderate level of technological complexity) in two different small states (in an advanced (Belgium) - and less advanced (Estonia) socio-economic contexts). - - 2019-05-28, ongoing project - - - 2017-05-29 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Belgium - - - PATECH - - - H2020-MSCA-IF-2016 - - - 750378 - - - - - FONDAZIONE IRCCS ISTITUTO NEUROLOGICO CARLO BESTA - UNIVERSITEIT MAASTRICHT - FONDAZIONE IRCCS ISTITUTO NAZIONALE DEI TUMORI - OSPEDALE SAN RAFFAELE SRL - YALE UNIVERSITY - NEUROSCIENCE TECHNOLOGIES SLP - NsGene A/S - DI.V.A.L. TOSCANA SRL - CENTRE EUROPEEN DE RECHERCHE EN BIOLOGIE ET MEDECINE - ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA - - - EUR 3 354 464,57 - - - Molecule-to-man pain network - - - EUR 3 354 464,57 - - - Italy - Netherlands - Italy - Italy - United States - Spain - Denmark - Italy - France - Italy - - - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - - Neuropathic pain affects 5% of the general population and 40% of patients with neurological diseases, and has a key role in the pathophysiology of cancer pain that affects up to 50% of patients in the early disease stage and - 30% of survivors, causing an enormous social burden. Treatments are inadequate with less than 50% of patients achieving 50% of pain relief at best, while up to 30% of cancer pain patients experience insufficient analgesia. Signatures of individual - susceptibility to pain and analgesic responsiveness are urgently needed to improve patients’ management. Such advances are expected to originate from integrated clinical, basic science and entrepreneurial research readily translating scientific - findings into benefits for patients. To consolidate these aims, a new generation of scientists with wide knowledge in neuropathic pain, focused research skills and experience in the interaction with biotechnology companies is needed. The PAIN-Net - programme, based on a highly innovative platform of training-through-research and strongly committed to such objectives, will support such talented and inspired early stage researchers. Their research projects, embedded in an advanced molecule-to-man - pain network, will contribute to better understanding individual susceptibility to pain and analgesics responsiveness based on next generation sequencing, whole exome sequencing, epigenetics and pharmacogenomics studies, nociceptor and sodium channel - functioning based on biophysics and proteomics studies, targeted analgesics based on high-throughput screening, targeted analgesic delivery based on encapsulated cell bioreactor implants, and to the development and extensive characterisation of the - first knock-in mouse models of sodium channel-related neuropathic pain based on the CRISP-Cas technology. Most of all, the PAIN-Net programme will offer the unique opportunity to enhance scientific capabilities and prepare to high level academic or - private applied research career. - - 2021-01-31, ongoing project - - - 2017-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Italy - - - PAIN-Net - - - H2020-MSCA-ITN-2016 - - - 721841 - - - - - TECHNISCHE UNIVERSITAET DRESDEN - TECHNISCHE UNIVERSITAET DRESDEN - - - EUR 2 500 000 - - - Chiral Morphogenesis - Physical Mechanisms of Actomyosin-Based Left/Right Symmetry Breaking in Biological Systems - - - EUR 2 500 000 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The aim of this grant is to understand how cellular, tissue-scale and organismal left-right asymmetry arises from the chirality of molecular constituents. In many instances the actomyosin cortex, a thin and mechanically active - layer of dynamically cross-linked filaments and molecular motors at the surface of cells, drives the emergence of chiral morphogenetic events. In the nematode Caenorhabditis elegans, mesoscale chiral active torques generated by this active layer - establish the embryo’s left-right body axis. Here we want to understand how mesoscale actomyosin active torques are generated at the molecular level, and how active torque generation in the actomyosin surface drives chiral morphogenesis of cells, - tissues and organisms. Cells and tissues represent a new class of active chiral materials where both the force and the torque balance need to be considered, and we will perform a systematic and cross-scale characterization of active chiral biological - matter. We will pursue an interdisciplinary approach at the interface of physics and biology. At the molecular-scale, we will use optical tweezers to measure active torques generated by single molecules of the molecular myosin and the actin - polymerizing protein formin. At the cell-scale, we will reconstitute chiral actomyosin flows in vitro and characterize chiral dynamics of single molecules in vivo. At the tissue-scale, we will investigate chiral cell movements in a multicellular - environment and unravel the physical basis of chiral tissue flow in vertebrates. Theory is essential at all stages, and we will build a molecular-scale model of actomyosin torque generation that will be coarse-grained to a generalized hydrodynamic - description of active chiral matter. This interdisciplinary and cross-scale approach will provide fundamentally new insights into active chiral materials and the mechanisms by which left-right asymmetries arise in development. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - CHIMO - - - ERC-2016-ADG - - - 742712 - - - - - FUNDACION PRIVADA INSTITUTO DE SALUD GLOBAL BARCELONA - - - EUR 158 121,60 - - - Unraveling the protein glycosylation of Plasmodium falciparum is crucial for development of novel therapeutics against malaria - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - Annually, malaria causes 200 million clinical cases and more than half a million deaths. Works carried out more than 40 years ago demonstrated that a malaria vaccine offering sterile protective immunity in humans was possible, - but the efforts to develop a modern, recombinant ‘subunit’ malaria vaccine only confer short term protection against clinical malaria in 35-50% of recipients. Several evidences support the presence of foreign short N-glycans and other minor - glycosylations in the surfaces of the parasite, Plasmodium faciparum, the causative agent of malaria. In addition, recent studies show that Plasmodium sporozoites present also unknown α-galactose containing antigens in their surface and that - antibodies against them provide sterile protection against malaria in mice. We propose to completely characterize the protein glycosylation present in the surface of the extracellular sporozoites, that travel from the mosquito to the liver, and - merozoites, that invade human erythrocytes. We will use different quasi-targeted glycoproteomic approaches, based on the expected simplicity and low variability of these glycosylations in the parasite surface and their affinity to well characterized - lectins. The investigation of these uncommon parasitic glycosylations may expose an unexpected Achilles’ heel in the Plasmodium parasite that could be exploited to halt sporozoite development and/or stop merozoite invasion and induce protection - against malaria, mimicking what has already been achieved using carbohydrate-protein conjugate vaccines against bacterial infections. - - 2018-08-28, ongoing project - - - 2016-08-29 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - SugarBlock - - - H2020-MSCA-IF-2015 - - - 703305 - - - - - EUROPEAN UNIVERSITY INSTITUTE - EUROPEAN UNIVERSITY INSTITUTE - - - EUR 829 000 - - - Oligopoly Markets and Networks - - - EUR 829 000 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Via our connections we learn about new ideas, quality of products, new investment opportunities and job opportunities. We influence and are influenced by our circle of friends. Firms are interconnected in complex processes of - production and distribution. A firm’s decisions in a supply chain depends on other firms’ choices in the same supply chain, as well as on firms' behaviour in competing chains. Research on networks in the last 20 years has provided a series of tolls - to study a system of interconnected economic agents. This project will advance the state of the art by further developing new applications of networks to better understand modern oligopoly markets. - - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Italy - - - Connections - - - ERC-2016-COG - - - 724356 - - - - - UNIVERSITY OF STRATHCLYDE - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - ZILINSKA UNIVERZITA V ZILINE - UNIVERZITET U NOVOM SADU FAKULTET TEHNICKIH NAUKA - SCHEIDT & BACHMANN SLOVENSKO S.R.O. - RAMBOLL UK LIMITED - PANONIT DOO ZA SISTEME ZASNOVANE NA RACUNARU RAZVOJ I PROIZVODNJU U OBLASTI INFORMACIONIH TEHNOLOGIJA - - - EUR 832 500 - - - SENSors and Intelligence in BuLt Environment - - - EUR 859 500 - - - United Kingdom - Spain - Slovakia - Serbia - Slovakia - United Kingdom - Serbia - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The goal of this project is to develop novel information sensing research and innovation approaches for acquiring, communicating and processing a large volume of heterogeneous datasets in the context of smart buildings, by - building an international, inter-disciplinary and inter-sectoral collaboration network through research and innovation staff exchanges and seamless exchange of ideas, expertise, data, testbeds, and know-how. - - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - United Kingdom - - - SENSIBLE - - - H2020-MSCA-RISE-2016 - - - 734331 - - - - - UNIVERSIDADE DE LISBOA - UNIVERSIDADE DO PORTO - UNIVERSIDADE DO MINHO - NOVA ID FCT - ASSOCIACAO PARA A INOVACAO E DESENVOLVIMENTO DA FCT - INSTITUTO UNIVERSITARIO DE LISBOA - CAMARA MUNICIPAL DE LISBOA - - - EUR 159 750 - - - Science in everyday life - - - EUR 159 750 - - - Portugal - Portugal - Portugal - Portugal - Portugal - Portugal - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - SCILIFE – Science in Everyday Life – is a European Researchers’ Night (ERN) proposal. It builds on previous experience of successful editions to bring ERN’s aims to a different level in the Portuguese context. Using the theme - of Science in Everyday Life as a point of departure, SCILIFE will address ‘traditional’ science and society issues – e.g. citizens’ engagement with sustainable and inclusive research, scientific careers, society’s involvement in science policy, - decision-making and collective deliberation – but it will do so by bringing Responsible Research and Innovation (RRI) strategically into the public debate. - - - 2017-11-30, closed project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.5."> - - - MSCA-NIGHT-2016 - European Researchers' Night - - - CSA - Coordination and support action - - - Portugal - - - SCILIFE - - - H2020-MSCA-NIGHT-2016 - - - 723006 - - - - - ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA - CARDIFF UNIVERSITY - CONSIGLIO NAZIONALE DELLE RICERCHE - ELVESYS SAS - TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY - FUNDACIO PRIVADA INSTITUT CATALA D'INVESTIGACIO QUIMICA - CHIROTECH TECHNOLOGY LIMITED - UNIVERSITA DEGLI STUDI DI TRIESTE - KATHOLIEKE UNIVERSITEIT LEUVEN - - - EUR 3 630 212,28 - - - ENTREPRENEURING DYNAMIC SELF-ORGANIZED INTERFACES IN PHOTOCATALYSIS: A MULTIDISCIPLINARY TRAINING NETWORK CONVERTING LIGHT INTO PRODUCTS - - - EUR 3 630 212,28 - - - Italy - United Kingdom - Italy - France - Israel - Spain - United Kingdom - Italy - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The global need to move current human technologies into a sustainable future will have a great impact for the world of chemistry and related industries. In close concert with other disciplines, chemistry will be increasingly - solicited to identify solutions that are practical, affordable and ultimately sustainable. To meet these objectives, not only research, but also chemical education will need profound reforms that have to be contextualized in the multidisciplinary and - intersectoral picture of a sustainable development. It is propelled by these societal needs that, by educating and practising 14 ESRs, PHOTOTRAIN will ensure photo-triggered chemical process to play its central role in sustainability. By capitalising - on the basic principles of supramolecular chemistry to program dynamic self-organized photoactive interfaces, it is intended to raise the creativity, knowledge, skills and capacity of the ESRs to conceive new ideas for reforming current industrial - transformations into a new generation of “light-triggered” processes. The challenge of developing and transferring light-fuelled processes from a proof-of-principle to an exploitable process is to embark upon a dynamic configuration in which - photoactive species are kept separated, act independently and are finally recycled. In particular, through the adoption of a microfluidic system in which programmed different phases allow the formation of photoactive interfaces, it is planned to - implement photo-catalytic technologies at the industrial level for triggering stereoselective organocatalytic transformations (i.e., pharmaceutical applications) and/or solar fuels production. By the organisation of targeted individual projects and - interdisciplinary secondements, ESRs will be guided toward attractive early-stage career opportunities as researchers, process chemists, chemical engineers and research managers in collective forms at various academic and research institutes, small - and large enterprises, and NGOs. - - 2020-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Italy - - - PHOTOTRAIN - - - H2020-MSCA-ITN-2016 - - - 722591 - - - - - ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA - UNIVERSITE CATHOLIQUE DE LOUVAIN - OROBOROS INSTRUMENTS GmbH - JUSTUS-LIEBIG-UNIVERSITAET GIESSEN - GEMEINNUTZIGE SALZBURGER LANDESKLINIKEN BETRIEBSGESELLSCHAFT - KAROLINSKA INSTITUTET - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - BIOCRATES LIFE SCIENCES AG - AvantiCell Science Ltd - UNIVERSITE DE BORDEAUX - - - EUR 2 856 812,04 - - - TRANSlating the role of Mitochondria in Tumorigenesis - - - EUR 2 856 812,04 - - - Italy - Belgium - Austria - Germany - Austria - Sweden - United Kingdom - Austria - United Kingdom - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - The consolidation of the knowledge that cancer is not only a genetic, but also a metabolic disease, has led scientists to investigate the intricate metabolic plasticity that transformed cells must undergo to survive the - adverse tumor microenvironment conditions, and the contribution of oncogenes and tumor suppressors in shaping metabolism. In this scenario, genetic, biochemical and clinical evidences place mitochondria as key actors in cancer metabolic - restructuring, not only because these organelles have a crucial role in the energy and biosynthetic intermediates production but also because occurrence of mutations in metabolic enzymes encoded by both nuclear and mitochondrial DNA has been - associated to different types of cancer. TRANSMIT aims to dissect the metabolic remodeling in human cancers, placing the focus on the role of mitochondria and bridging basic research to the improvement/development of therapeutic strategies. Further, - TRANSMIT fosters the communication of this emerging field to the patients and their families. To these aims, TRANSMIT will create a network of seven different countries, among which world-leading basic science and clinical centers of excellence, - several industrial partners with up-to-date omics technologies, as well as non-profit foundations and associations who care for cancer patients. By creating the critical mass of scientific excellence, TRANSMIT will allow to transfer the current - knowledge into the wide field of cancer research, translating scientific and technical advances into the education and training of eleven Early Stage Researchers. TRANSMIT will implement training-through-research dedicated to unravel the metabolic - features of cancer, as well as to provide a full portfolio of complementary skills through the creation of a network of basic, translational and industrial laboratories, devoted to a multidisciplinary/multisectorial education of young scientists. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Italy - - - TRANSMIT - - - H2020-MSCA-ITN-2016 - - - 722605 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE UNIVERSITY OF WARWICK - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - - - EUR 1 983 400 - - - Productivity and Development: The Ready-made Garment Productivity Project - - - EUR 1 983 402,25 - - - United Kingdom - United Kingdom - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Differences in productivity explain much of differences in income levels across countries, yet little is known about how to improve productivity of manufacturing in the developing world. Recent research reveals very high - dispersion in productivity in low-income countries. We examine firm productivity at a uniquely detailed level, collecting sub-factory production and survey data from hundreds of garment manufacturers in several countries. The data, coupled with a new - method for comparing productivity, allow us to measure physical productivity in and across firms and among heterogeneous products. Initial results from nearly 100 factories in Bangladesh show significant dispersion of productivity within factories; - production lines at the 90th percentile are 50% more efficient than those at the 10th percentile. Differences are highly persistent – puzzling given that the lines are often on the same production floor. Capital and the quality of the buyer explains - a small part of the dispersion: lines producing goods for higher-end buyers are significantly more efficient. - - 2020-11-30, ongoing project - - - 2015-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - RMGPP - - - ERC-2014-ADG - - - 669746 - - - - - EBERHARD KARLS UNIVERSITAET TUEBINGEN - - - EUR 171 460,80 - - - Gen Duplication and Amplification in Staphylococcal populations - - - EUR 171 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - Bacterial pathogens possess the ability to adapt rapidly to changing environmental conditions which is especially apparent in the hospital setting where bacteria acquire antibiotic resistances readily. Besides well studied - mechanisms such as horizontal gene transfer bacteria can alter the genetic material by acquiring gen duplications and amplifications (GDA). Exemplarily an improved gene dosage of a minor resistance determinant can lead to increased resistance to - antibiotics. Due to the difficulties in their detection GDAs are almost exclusively studied in model organisms and neglected in natural populations of clinically relevant species such as Staphylococcus aureus. Accordingly many important questions - about the frequency and clinical importance of GDAs remain unanswered. State of the art sequencing technologies enable the identification of GDAs by analysis of the coverage scaffold and groundbreaking experiments using 387 USA300 genome sequences - showed promising results regarding putative copy number variation of virulence factors. We will extend the GDA analysis to ca. 1200 already available EMRSA15 sequences. This will enable a comprising analysis of gen copy number variation in clinical - isolates and might allow identifying genomic regions under strong evolutionary pressure during infection. We will optimize experimental setups for the rapid validation of GDAs by qPCR and develop techniques to study the effects of GDAs in S. aureus. - Furthermore we will sequence a selection ca. 70 S. aureus isolates causing chronic infections in patients suffering from cystic fibrosis (CF). This will enable us to optimize the detection of GDAs by NGS and will allow investigating the role of GDAs - during adaption to the complex environment within the CF-lung. This project will show new avenues to extract additional valuable biological information from NGS data and will investigate the importance of GDAs during the adaption of S. aureus to the - hospital setting and to the CF-lung. - - 2017-12-31, closed project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - GDA in staphylococci - - - H2020-MSCA-IF-2014 - - - 655978 - - - - - BIOMEDICAL SCIENCES RESEARCH CENTER ALEXANDER FLEMING - BIOMEDICAL SCIENCES RESEARCH CENTER ALEXANDER FLEMING - - - EUR 1 500 000 - - - A genomics and systems biology approach to explore the molecular signature and functional consequences of long-term, structured fasting in humans - - - EUR 1 500 000 - - - Greece - Greece - - - Research Organisations - Research Organisations - - Dietary intake has an enormous impact on aspects of human health, yet scientific consensus about how what we eat affects our biology remains elusive. To address the complex biological impact of diet, I propose to apply an - unconventional, ‘humans-as-model-organisms’ approach to compare the molecular and functional effects of a highly structured dietary regime, specified by the Eastern Orthodox Christian Church (EOCC), to the unstructured diet followed by the general - population. Individuals who follow the EOCC regime abstain from meat, dairy products and eggs for 180-200 days annually, in a temporally-structured manner initiated in childhood. I aim to explore the biological signatures of structured vs. - unstructured diet by addressing three objectives. First I will investigate the effects of the two regimes, and of genetic variation, on higher-level phenotypes including anthropometric, physiological and biomarker traits. Second, I will carry out a - comprehensive set of omics assays (metabolomics, transcriptomics, epigenomics and investigation of the gut microbiome), will associate omics phenotypes with genetic variation, and will integrate data across biological levels to uncover complex - molecular signatures. Third, I will interrogate the functional consequences of dietary regimes at the cellular level through primary cell culture. Acute and long-term effects of dietary intake will be explored for all objectives through a two - timepoint sampling strategy. This proposal therefore comprises a unique opportunity to study a specific perturbation (EOCC structured diet) introduced to a steady-state system (unstructured diet followed by the general population) in a - ground-breaking human systems biology type of study. This approach brings together expertise from genomics, computational biology, statistics, medicine and epidemiology. It will lead to novel insights regarding the potent signalling nature of - nutrients and is likely to yield results of high translational value. - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Greece - - - FastBio - - - ERC-2016-STG - - - 716998 - - - - - KING'S COLLEGE LONDON - - - EUR 195 454,80 - - - Strategic U-Turns between the EU and Russia: Explanatory Prospects of Prospect Theory - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - "The project attempts to test the potential of prospect theory in explaining the strategic choices of countries located in the common neighbourhood between the European Union (EU) and Russia. Under what conditions ruling - elites in Eastern Partnership (EaP) countries select EU or Eurasian Economic Union (EaEU) as integration projects? The theoretical expectation is that different values of gains and losses, judged against a given ""reference point"", are associated - with one or another integration project and may be at work in the selection of strategic choices of EaP countries. Prospect theory, a Nobel Prize-winning theoretical construct, has roots in cognitive psychology, but it has uncovered its extraordinary - potential to explain decisions under conditions of uncertainly and risk in behavioural economics. The attempts of importing the insights of prospect theory into political science are slowly growing, but there is yet a long way ahead until political - science will fully integrate them into its ontological agenda. The proposed project is going to be a pioneering application of prospect theory to the strategic alternatives faced by countries located in the common neighbourhood between the EU and - Russia." - - 2020-02-29, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - EUEaPRU - - - H2020-MSCA-IF-2016 - - - 746909 - - - - - AALTO-KORKEAKOULUSAATIO - - - EUR 267 793,20 - - - Advanced Wide-Band Transceiver Architectures for Beyond 5G Wireless Systems - - - EUR 267 793,20 - - - Finland - - - Higher or Secondary Education Establishments - - The fifth generation and beyond radio systems targets 1000 times traffic volumes compared to present state-of-the-art. In order to guarantee the quality of service, communication capacity leap of three orders of magnitude - requires sophisticated interference management and communication channel protection from the interference generated by other users. The objective of this project is to develop integrated transceiver hardware structures for massive MIMO/beam forming - antenna arrays, supporting agile carrier aggregation, digitally assisted interference management, and full duplex communication, thus enhancing communication efficiency in spatial, temporal and frequency domains. - - - 2020-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Finland - - - ADVANTAG5 - - - H2020-MSCA-IF-2015 - - - 704947 - - - - - ANGLIA RUSKIN UNIVERSITY HIGHER EDUCATION CORPORATION - - - EUR 97 727,40 - - - Shaping a Preferable Future: Children Reading, Thinking and Talking aboutAlternative Communities and Times - - - EUR 97 727,40 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Despite overall agreement that children’s voices matter in the development of policies affecting them, little effort has been made to develop cultural practices encouraging utopianism as a critical attitude to reality and a - means of facilitating the expression of formative opinions on the part of children. Nor have young readers’ interpretations of utopian literature been investigated as indicating their perception of the sociopolitical arrangements around them, - including the context of the EU. - - 2018-08-20, ongoing project - - - 2017-08-21 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ChildAct16 - - - H2020-MSCA-IF-2016 - - - 745888 - - - - - GOLDSMITHS' COLLEGE - GOLDSMITHS' COLLEGE - - - EUR 149 995 - - - Transforming Gender Justice for Conflict-Related Sexual Violence: The Gender Justice Prototype Framework for Analysis and Action - - - EUR 149 995 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - How to provide justice for conflict-related sexual violence (CRSV) has now become a highly visible and challenging global problem with few solutions. The TRANSFORM project addresses this problem by creating a prototype Gender - Justice Framework to guide analysis of, and responses to, conflict-related sexual violence. The ERC Gender of Justice Project (GoJ) provides a unique array of justice indicators and innovative methods that can deliver ground-breaking strategies to - combat impunity for conflict-related sexual violence. The prototype Framework exploits these cutting edge analytics and insights by building them into an integrated package of guiding principles and tools for policy-makers and practitioners. These - ‘how to’ guides and instruments map patterns of sexual violence and affected groups, assess the adequacy of criminal and social justice responses, and generate new justice strategies. This prototype framework for analysis and action in this difficult - field has wide application for those working in the human rights, international criminal law, transitional justice, and peace building and security sectors in conflict-affected contexts. - - 2019-02-28, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - TRANSFORM - - - ERC-2016-PoC - - - 737515 - - - - - UNIVERSITA CA' FOSCARI VENEZIA - - - EUR 229 761 - - - Atlas of Renaissance Antiquarianism - - - EUR 229 761 - - - Italy - - - Higher or Secondary Education Establishments - - ATRA - Atlas of Renaissance Antiquarianism is a digital system that will map the circulation of antiquarian learning in sixteenth-century Europe. Its purpose is to contribute to the promotion of new knowledge on antiquarian - studies in the Renaissance and demonstrate how the antiquarian approach – that based the growth of thought on documented sources and empirical evidence – played a primary role in the evolution of the entire cultural/intellectual life of Early Modern - times. The main intent is to allow the interconnection of data that otherwise would probably never come into contact and to bring to the surface issues not yet bridled in rigid classifications. This will enable the discovery of new cultural - itineraries and convergences in Renaissance scholarship; trace the paths that led to parallel or independent ideas; and uncover new trends of thought that can help us better understand the evolution of European civilization and spirit. - - - 2020-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Italy - - - ATRA - - - H2020-MSCA-IF-2016 - - - 745704 - - - - - WEIZMANN INSTITUTE OF SCIENCE - WEIZMANN INSTITUTE OF SCIENCE - - - EUR 150 000 - - - ImmuNogenomics TArgeting Cancer - - - EUR 150 000 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Melanoma is the most aggressive, treatment-resistant and lethal type of skin cancer. Its increasing incidence worldwide emphasizes the need for new treatment strategies. Major recent breakthroughs in melanoma therapy have - highlighted the role of immune T cell-mediated responses against tumor cells, showing that immune-system recognition of neo-antigens on cancer cells serves as a distinctive immunological signature. However, current strategies to identify neo-antigens - are biased, costly and time-consuming. Directly addressing this major therapeutic limitation, this PoC project is aimed at commercializing an innovative tool, called INTACt, for designing highly personalized therapies for melanoma patients, ones that - efficiently target the composition of patient-specific neo-antigens that arise as a consequence of mutations in a patient’s melanoma genome. INTACt is designed to identify neo-antigens in a high-throughput, systematic and cost-effective manner in - cell lines, fresh tumors, patient-derived xenografts and plasma. INTACt will further identify the patient neo-antigen-reactive T cells to then be returned to the patient, using neo-antigen-specific T cells or RNA vaccines. Such personalized targeting - of the patient’s melanoma genetic landscape is key to a significantly improved mortality. Unlike existing therapeutic strategies, INTACt may be considered the ultimate personalized immune therapy for the treatment of melanoma patients to be expended - to other cancer types. This patient-specific tool will significantly lower patients’ economic and psychological burden caused by unnecessary chemotherapy and targeted therapy. INTACt also holds the promise of realizing value from enormous past - investments in drug candidates that were eliminated due to person-specific toxicities or lack of efficacy as these can be combined with the neo-antigen-based immunotherapy. INTACt will thus enable the creation of new business models for the highly - pressured pharmaceutical industry. - - 2018-11-30, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Israel - - - INTACt - - - ERC-2016-PoC - - - 754282 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 149 159 - - - CAPITA: Child Abuse Prevention International Training and Access - - - EUR 149 159 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This Proof of Concept proposal is a rare opportunity to translate social program innovation into international impact. Every year, a billion children worldwide are victims of child abuse. The highest rates are in - low-and-middle-income countries, affecting children of all ages (WHO, 2012). A small number of child abuse prevention programs for young children have been tested in high-income countries and commercialized. This makes them inaccessible to the vast - majority of families at risk of abuse in the developing world. - - 2019-03-31, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - CAPITA - - - ERC-2016-PoC - - - 737476 - - - - - TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY - TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY - - - EUR 150 000 - - - User behavior Simulation in built Environments - - - EUR 150 000 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The impact of a building design or renovation on the behavior of its intended occupants can be assessed only after the building has been built and occupied (or the renovation has been completed). This is a risky proposition, - because design mistakes can cause severe consequences in terms of under-performing buildings, reduced productivity, absenteeism, and general user dissatisfaction. During our ERC-funded project, titled NextGenBim, we were able to develop and - demonstrate a method to computationally simulate human behavior in built environments, which allows representing the intended occupants and their activities in a given building. In this PoC we aim to develop a software simulator that allows: (1) to - visualize, analyze and evaluate trade-offs between several design options for a new building; and (2) to evaluate the systemic implication of proposed renovations on the operations of a building. The software will potentially impact millions of - professionals (architects, civil engineers, internal designers, facility mangers, etc.), especially in the healthcare sector, where large budgets are spent to build and renovate facilities, and in the educational sector, which invests heavily in - computer-aided design software to train the next generation of professionals. - - 2018-11-30, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Israel - - - USE - - - ERC-2016-PoC - - - 754696 - - - - - TECHNISCHE UNIVERSITAET DRESDEN - TECHNISCHE UNIVERSITAET DRESDEN - - - EUR 2 363 125 - - - Understanding negative gas adsorption in highly porous networks for the design of pressure amplifying materials - - - EUR 2 363 125 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Negative gas adsorption (NGA) is a new, counterintuitive and paradoxical phenomenon, for the first time reported by my group in 2016: Normal solid materials with significant outer or inner surface area always take up gas when - the pressure in the surrounding reservoir is increased (adsorption). NGA networks instead react at a certain point in the opposite direction: They release gas upon external pressure increase, leading to an overall pressure amplification in a closed - system. Comparable phenomena have never been reported before. What is so exciting about NGA? We have a unique material in hand, that counteracts to an external force by force amplification. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - AMPLIPORE - - - ERC-2016-ADG - - - 742743 - - - - - ECOLE NORMALE SUPERIEURE - ECOLE NORMALE SUPERIEURE - - - EUR 2 500 000 - - - Molecules, magnetic fields and Intermittency in coSmic Turbulence – Following the energy trail. - - - EUR 2 500 000 - - - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The discovery of molecules in the early universe is a challenging providence. Molecules unveil the truly cold universe in which stars form and their rich versatility provides unique diagnostics to unravel the ”relative - importance of purely gravitational effects and gas dynamical effects involving dissipation and radiative cooling”, recognized 40 years ago by White and Rees to be a central issue in theories of galaxy formation. Molecules also reveal that cosmic - turbulence is far less dissipative than predicted by cosmological simulations, with a broad equipartition in a vast variety of media between the thermal energy of the hottest phases and the turbulent energy of the coldest. Our project focuses on the - physics of turbulent dissipation, and its link to the emergence of molecules, in the magnetized compressible medium where gravitational instability develops to form stars and seed galaxies in the early universe. It builds on a fundamental property of - turbulence, its space-time intermittency: dissipation occurs in bursts. Our team will foster strong interactions between three main research axes: (1) observations of the chemical and thermal markers of turbulent dissipation in the high-redshift and - local universe, (2) statistical analyses of the magnetic and velocity fields in samples of unprecedented size and sensitivity to study the non-Gaussian signatures of turbulent dissipation, and (3) numerical experiments dedicated to (a) the space-time - structures of turbulent dissipation and the formation of molecules in their wake, and (b) the split of the energy trails between hot/thermal and cold/turbulent phases. This project will benefit from the prodigious capabilities of the ALMA and NOEMA - interferometers, the launch of the JWST in 2018, and the Planck satellite data on polarized Galactic foregrounds. The ENS Physics Department, with its strong theoretical and experimental expertise on turbulence, is an ideal place to house such a - project. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - France - - - MIST - - - ERC-2016-ADG - - - 742719 - - - - - UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6 - UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6 - - - EUR 2 192 500 - - - Asymptotic approach to spatial and dynamical organizations - - - EUR 2 192 500 - - - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The understanding of spatial, social and dynamical organization of large numbers of agents is presently a fundamental issue in modern science. ADORA focuses on problems motivated by biology because, more than anywhere else, - access to precise and many data has opened the route to novel and complex biomathematical models. The problems we address are written in terms of nonlinear partial differential equations. The flux-limited Keller-Segel system, the integrate-and-fire - Fokker-Planck equation, kinetic equations with internal state, nonlocal parabolic equations and constrained Hamilton-Jacobi equations are among examples of the equations under investigation. - - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - France - - - ADORA - - - ERC-2016-ADG - - - 740623 - - - - - UNIVERSITEIT UTRECHT - UNIVERSITEIT UTRECHT - - - EUR 2 000 000 - - - Addressing Antibiotic Resistance: New Strategies for Overcoming the ESKAPE Pathogens - - - EUR 2 000 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Antibiotic resistance poses an alarming threat to global health. Most worrisome are the so-called “ESKAPE” pathogens (E. faecium, S. aureus, K. pneumoniae, A. baumanii, P. aeruginosa, and Enterobacter species), a collection of - organisms capable of escaping the effects of almost all conventional antibiotics. Key to combating drug-resistant bacteria is the identification of new antibacterial targets and the ability to exploit these targets with novel and unconventional - antibiotics. - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - NO-ESKAPE - - - ERC-2016-COG - - - 725523 - - - - - STICHTING KATHOLIEKE UNIVERSITEIT BRABANT - STICHTING KATHOLIEKE UNIVERSITEIT BRABANT - - - EUR 1 999 747,50 - - - Innovative Methods for Psychology: Reproducible, Open, Valid, and Efficient - - - EUR 1 999 747,50 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - With numerous failures to replicate, common misreporting of results, widespread failure to publish non-significant results or to share data, and considerable potential bias due the flexibility of analyses of data and - researcher’s tendency to exploit that flexibility, psychological science is said to experience a crisis of confidence. These issues lead to dissemination of false positive results and inflate effect size estimates in meta-analyses. This leads to poor - theory building, an inefficient scientific system, a waste of resources, lower trust in psychological science, and psychology’s outcomes being less useful for society. After having contributed to the literature highlighting these problems the goal of - my ERC project is to improve psychological science by offering novel solutions to five vexing challenges: (1) I want to counter misreporting of results by using our new tool statcheck in several studies on reviewers’ tendency to demand perfection and - by applying it to actual peer review. (2) I want to counter the biasing effects of common explorations of data (p-hacking) by professing and studying pre-registration and by developing promising new approaches called blind analysis and - cross-validation using differential privacy that simultaneously allows for exploration and confirmation with the same data. (3) I want to counter the common problem of selective outcome reporting in psychological experiments by developing powerful - latent variable methods that render it fruitless to not report all outcome variables in a study. (4) I want to counter the problem of publication bias by studying and correcting misinterpretations of non-significance. (5) I want to develop and refine - meta-analytic methods that allow for the correction of biases that currently inflate estimates of effects and obscure moderation. The innovative tools I develop have the potential to improve the way psychologists (and other scientists) analyse data, - disseminate findings, and draw inferences. - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - IMPROVE - - - ERC-2016-COG - - - 726361 - - - - - OSPEDALE SAN RAFFAELE SRL - OSPEDALE SAN RAFFAELE SRL - - - EUR 2 390 000 - - - Functional Biology of Hepatic CD8+ T cells - - - EUR 2 390 000 - - - Italy - Italy - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - CD8+ T cells have a key role in eliminating intracellular pathogens and tumors that affect the liver. The protective capacity of these cells relies on their ability to migrate to and traffic within the liver, recognize - pathogen- or tumor-derived antigens, get activated and deploy effector functions. While some of the rules that characterize CD8+ T cell behavior in the infected and cancerous liver have been characterized at the population level, we have only limited - knowledge of the precise dynamics of intrahepatic CD8+ T cell conduct at the single-cell level. In preliminary data for this project we have developed several advanced imaging techniques that allow us to dissect the interactive behavior of CD8+ T - cells within the mouse liver at an unprecedented level of spatial and temporal resolution. We predict that this approach, combined with unique models of hepatitis B virus pathogenesis and a new model of hepatocellular carcinoma created ad hoc for - this proposal, will generate novel mechanistic insights into the spatiotemporal determinants that govern the capacity of CD8+ T cells to home and function in the virus- or tumor-bearing liver. Specifically, we plan to pursue two main goals: 1) To - assess how the anatomical, hemodynamic and environmental cues that characterize hepatocellular carcinomas shape CD8+ T cell behavior and function; 2) To characterize intrahepatic T cell priming events that induce functionally defective T cell - responses. Results emerging from these studies will advance our knowledge on how adaptive immunity mediates pathogen clearance and tumor elimination. This new knowledge may lead to improved vaccination and treatment strategies for immunotherapy of - infectious diseases and cancer. - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Italy - - - FATE - - - ERC-2016-COG - - - 725038 - - - - - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH - 3D PLUS SA - JYVASKYLAN YLIOPISTO - KATHOLIEKE UNIVERSITEIT LEUVEN - RIJKSUNIVERSITEIT GRONINGEN - UNIVERSITE DE MONTPELLIER - FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG - - - EUR 3 889 953 - - - RADiation and reliability challenges for electronics used in Space, Avionics, on the Ground and at Accelerators - - - EUR 3 889 953 - - - Switzerland - France - Finland - Belgium - Netherlands - France - Germany - - - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Reliability and radiation damage issues have a long and important history in the domain of satellites and space missions. Qualification standards were established and expertise was built up in space agencies (ESA), supporting - institutes and organizations (CNES, DLR, etc.) as well as universities and specialized companies. During recent years, radiation concerns are gaining attention also in aviation, automotive, medical and other industrial sectors due to the growing - ubiquity and complexity of electronic systems and their increased radiation sensitivity owing to technology scaling. This raises the demand for dedicated design and qualification guidelines, as well as associated technical expertise. Addressing open - questions linked to respective qualification requirements, the proposed training network “RADiation and Reliability - - 2021-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Switzerland - - - RADSAGA - - - H2020-MSCA-ITN-2016 - - - 721624 - - - - - UNIVERSITA DEGLI STUDI DI GENOVA - UNIVERSIDAD NACIONAL DE EDUCACION A DISTANCIA - MIDDLE EAST TECHNICAL UNIVERSITY - UNIVERSIDAD COMPLUTENSE DE MADRID - UNIVERSIDADE DO MINHO - UNIVERSITAT LINZ - UNIVERSITA DEGLI STUDI DI BRESCIA - ASSOCIAZIONE ITALIANA PER L ASSISTENZA AGLI SPASTICI PROVINCIA DI BOLOGNA - FISH - FEDERAZIONE ITALIANA PER IL SUPERAMENTO DELL'HANDICAP ASSOCIAZIONE - ASOCIACION DE FAMILIARES Y AMIGOS DE PERSONAS CON DISCAPACIDAD DE LA UNIVERSIDAD COMPLUTENSE DE MADRID (AFADIS UCM) - FRATERNA - CENTRO COMUNITARIO DE SOLIDARIEDADE E INTEGRACAO SOCIAL, CIPRL - VEREIN ZUR FOERDERUNG ASSISTIERENDER TECHNOLOGIE IN EUROPA - FUNKA NU AB - ENGELLI KADIN DERNEGI - A.I.SM. ASSOCIAZIONE ITALIANA SCLEROSI MULTIPLA ONLUS - STOCKHOLMS UNIVERSITET - - - EUR 1 809 000 - - - RISEWISE -RISE Women with disabilities In Social Engagement - - - EUR 1 809 000 - - - Italy - Spain - Turkey - Spain - Portugal - Austria - Italy - Italy - Italy - Spain - Portugal - Austria - Sweden - Turkey - Italy - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - Other - Other - Other - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Other - Higher or Secondary Education Establishments - - Women with disabilities have more difficulties to find an employment and to integrate in social day life activities than men with disabilities. - - 2020-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Italy - - - RISEWISE - - - H2020-MSCA-RISE-2015 - - - 690874 - - - - - FUNDACION BCMATERIALS - BASQUE CENTRE FOR MATERIALS, APPLICATIONS AND NANOSTRUCTURES - - - EUR 158 121,60 - - - Smart Alloys Surface Patterning for Properties Tuning - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - The SASPAT project presents two main goals: (a) to train the talented young researcher Dr. Jose M. Porro, in the attractive growing field of Magnetic Shape Memory Alloys (MSMAs), where the host and partner institutions have - developed their expertise and knowledge; and (b) the design, development and optimisation of smart patterned MSMA surfaces for applications in industrial sectors such as microfluidics and optical microswitching. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - SASPAT - - - H2020-MSCA-IF-2016 - - - 753025 - - - - - LANCASTER UNIVERSITY - KUNGLIGA TEKNISKA HOEGSKOLAN - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - UNIVERSITA DI PISA - UNIVERSITAT JAUME I DE CASTELLON - UNIVERSITA CATTOLICA DEL SACRO CUORE - BOGAZICI UNIVERSITESI - PHILIPS ELECTRONICS NEDERLAND B.V. - THE LEEDS TEACHING HOSPITALS NATIONAL HEALTH SERVICE TRUST - PLUX - WIRELESS BIOSIGNALS S.A. - - - EUR 3 888 273,60 - - - Personal Technologies for Affective Health - - - EUR 3 888 273,60 - - - United Kingdom - Sweden - Ireland - United Kingdom - Italy - Spain - Italy - Turkey - Netherlands - United Kingdom - Portugal - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Personalized health is a European priority and one of the strategic research areas for Horizon 2020. This project advances the state-of-the-art of personal health technologies for affective disorders, estimated to be the - highest ranking cause of disease by 2020. It marks a significant shift from the current wearable technologies capturing emotional responses whose understanding usually requires physicians’ input, to low-cost self-help technologies for visualizing, - exploring and regulating emotions. - - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - AffecTech - - - H2020-MSCA-ITN-2016 - - - 722022 - - - - - THE UNIVERSITY OF BIRMINGHAM - - - EUR 195 454,80 - - - Bridging Belief and Practice - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The aim of the proposed research is to bridge the gap between theoretical and empirical studies of religion, which up till now developed separately, as the studies of beliefs and the studies of practices. This will be done by - means of elucidating the properties of beliefs and their relation to human embodied religious practices. . I decided to take the best of empirical investigations (phenomenology and the most prominent results of religious studies) and the best of - theoretical investigation (analytic philosophy) and make a conceptual work to bridge them. As a methodological basis for this work I have chosen embodied approaches, as they present a link between phenomenological descriptions and strict analytical - conceptualizations. Body is a medium between beliefs and practices, thus the concept of belief will be developed in relation to the practice with a body as a focal point and a key source of conceptualizations. The results of the research will be - presented in clear-cut analytical terms, easy to use not only by empirical and theoretical researchers of religion, but also by participants of interreligious dialogue, thus contributing to mutual understanding and religious tolerance. I aim to - provide a proper, detailed and accurate account of the properties of beliefs in their relation to practice by conceptualizing the results of empirical studies in clear-cut analytical terms. This project is an important step in my professional - development, as for its fulfillment I will have to apply all my previous knowledge and interdisciplinary skills, and learn new analytic methods. - - 2017-09-27, closed project - - - 2015-09-28 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - BBP - - - H2020-MSCA-IF-2014 - - - 660954 - - - - - LIVERPOOL JOHN MOORES UNIVERSITY - - - EUR 183 454,80 - - - The cardiovascular consequences of endurance exercise - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Problem: Exercise training represents an attractive and low-cost strategy to improve cardiovascular health. Recent studies, however, report novel evidence that endurance exercise can lead to potentially detrimental cardiac - maladaptations. First, acute exercise-induced elevations in cardiac troponin (cTn) levels have been found, which typically reflect myocardial (micro-)damage and are predictive of future cardiovascular events and mortality. Secondly, myocardial - fibrosis has been reported in 12–50% of individuals engaged in lifelong exercise training, reflecting scarring of cardiac tissue that is typically found in patients with cardiovascular diseases (CVD). These cardiac maladaptations are highly - unexpected and largely unexplained in apparently healthy individuals. - - 2017-05-31, closed project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - CARDI-ACHE - - - H2020-MSCA-IF-2014 - - - 655502 - - - - - TECHNISCHE UNIVERSITEIT EINDHOVEN - INTEL BENELUX BV - PHILIPS MEDICAL SYSTEMS NEDERLAND BV - TECHNOLUTION BV - TECHNISCHE UNIVERSITAET MUENCHEN - INCHRON GMBH - FORTISS GMBH - TECHNISCHE UNIVERSITAT DORTMUND - KUNGLIGA TEKNISKA HOEGSKOLAN - IMSYS AB - ODYS SRL - - - EUR 3 820 273,63 - - - Platform-aware Model-driven Optimization of Cyber-Physical Systems - - - EUR 3 820 273,63 - - - Netherlands - Netherlands - Netherlands - Netherlands - Germany - Germany - Germany - Germany - Sweden - Sweden - Italy - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Many modern industrial systems fall in the realm of Cyber-Physical Systems (CPS) because of the tight interaction between computation, communication and control elements (the cyber part), and physical processes such as motion, - heating/cooling, vibration, wear and tear (the physical part) within these systems. Traditional design methods involve multiple, often isolated, design phases involving different disciplines (mechanical, electrical, control and software engineering). - Requirements related to cost, quality and reliability enforce designs with over-provisioning of platform resources (computation, communication, memory) by large margins at each phase to be able to fulfill system-level requirements in the worst-case - scenarios. To replace such overly conservative design process, there is an urgent need for integrative design trajectories that allow for tradeoffs between cost, quality and reliability coping with the tight coordination between the cyber and the - physical components. This gives rise to the need for models that accurately capture the interaction between various components (e.g., software, electronics, mechanics, algorithms, power, energy, etc.) and novel design methods that exploit the - artifacts of the underlying platforms. - - - 2019-10-31, ongoing project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Netherlands - - - oCPS - - - H2020-MSCA-ITN-2015 - - - 674875 - - - - - KOZEP-EUROPAI EGYETEM - - - EUR 146 239,20 - - - Dynamics of Development: Understanding Adolescents' Intergroup Attitudes, National Feelings, and Perception of Social Norms - - - EUR 146 239,20 - - - Hungary - - - Higher or Secondary Education Establishments - - Understanding the causes of prejudice is one of the main goals of social psychology. Recently, the interest of researchers turned to the development of prejudice which is highly important for the early prevention of intergroup - hostility. Most of these works focus on childhood and much less is known about the development of prejudice in adolescence even though it is a crucial period for the formation of the identity. In my previous research I was able to detect the process - of the crystallisation of prejudice among teenagers. Comparing age groups between 12 and 19 years, teenagers’ ethnic prejudices were found to become clearly more coherent by age. - - - 2018-05-31, ongoing project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Hungary - - - DYNADE - - - H2020-MSCA-IF-2014 - - - 658323 - - - - - EUROPEAN UNIVERSITY INSTITUTE - - - EUR 168 277,20 - - - Western Strategies in East Asia. The Reconfiguration of US, British and French security policies in the Pacific Century - - - EUR 168 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - The core question that this project tackles is how the three major Western military powers (the US, Britain and France) have adapted their security policies to the shifting center of strategic gravity of international politics - from the Euro-Atlantic area to the Asia-Pacific. In addressing this question, WESTRAT conducts a comparative analysis of their evolving security policies in confronting the main “traditional” and “non-traditional” security challenges in East Asia, - i.e. the rise of China, the proliferation of weapons of mass destruction and piracy. In so doing, this project makes three original contributions. (1) Firstly, WESTRAT offers an empirical contribution as the first work to provide a cross-national - comparison of the security policies of the three major Western powers (1990-2016) – in their national, bilateral, and multilateral configurations – in what is deemed to be the world’s new center of strategic gravity. It therefore investigates a - crucial yet under-explored dimension of contemporary international politics. (2) Secondly, it provides an innovative conceptual framework that sheds light on the emerging networks of national, bilateral and multilateral security arrangements (what we - label “networked security postures”) in international politics. It thereby contributes to the debates on the under-theorized relationships between bilateralism and multilateralism as venues for security cooperation. (3) Finally, given the absence of - a common European strategy toward the region, this project seeks to enrich the policy discussions in the European Union (EU) and to provide policy recommendations on how to bolster cooperation between the EU, its member states, and the US – and - transatlantic relations more generally – in developing a common strategy towards the (re)emergence of East Asia in world politics. Combining concepts and methods derived from international relations, from sociology, and from history, WESTRAT takes an - interdisciplinary perspective. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - WESTRAT - - - H2020-MSCA-IF-2016 - - - 752790 - - - - - "NATIONAL CENTER FOR SCIENTIFIC RESEARCH ""DEMOKRITOS""" - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH - KOBENHAVNS UNIVERSITET - A I ALIKHANYAN NATIONAL SCIENCE LABORATORY - NANJING UNIVERSITY - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - NATIONAL ACADEMY OF SCIENCES OF THE REPUBLIC OF ARMENIA - - - EUR 252 000 - - - Development and Implementation of new generation of Pseudo Random Number Generators based on Kolmogorov-Anosov K-systems - - - EUR 360 000 - - - Greece - Switzerland - Denmark - Armenia - China - Switzerland - Armenia - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Modern powerful computers open a new era for the application of the Monte Carlo method for the simulation of physical systems of higher complexity. The Monte Carlo simulations are important computational techniques in many - areas of natural sciences and have significant application in particle and nuclear physics, quantum physics, statistical physics, quantum chemistry, material science, among many other multidisciplinary applications. In the heart of the Monte Carlo - simulations are Pseudo Random Number Generators (RNG). The primary objective of the proposed network is a systematic development and implementation of the state of the art new generation of Pseudo Random Number Generators based on Kolmogorov-Anosov - K-systems, which demonstrates excellent statistical properties, into a multidisciplinary usable product. This innovative class of RNG was proposed earlier by the members of the network and relies on the fundamental discoveries and results of Ergodic - theory. In order to turn these ideas and earlier research on K-systems generators into a usable product the network undertakes the following actions: To develop an efficient program of the K-system generator with tunable internal parameters of - maximal dimensionality and of the order of the Galois field, embedded into a user friendly environment and with an on-line manual; To provide statistical data representing internal characteristics of the K-system generator as a function of the - dimensionality of the generator and of the order of the Galois field; To implement the K-system generator into the concurrent and distributed software at CERN for applications in LHC and other HEP experiments; To perform large scale simulations in - Quantum Gravity and Quantum Field Theory based on K-system generator. To disseminate the product at CERN and other research centers.These objectives will be achieved by secondments,exchange of knowledge, collective research and training between staff - members of the five partners. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Greece - - - MIXMAX - - - H2020-MSCA-RISE-2014 - - - 644121 - - - - - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - - - EUR 159 460,80 - - - Calibration of Astronomical Spectrographs with Stabilized Fabry-Perot Etalons - - - EUR 159 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - The “holy grail” of exoplanet research today is the detection of an Earth-like planet in the habitable zone of a Sun-like star. Doppler spectroscopy is an indispensable tool for finding and characterizing extrasolar planets; - however, detecting an Earth twin by measuring the radial velocity (RV) perturbation it imposes on the parent star requires nearly one order of magnitude better RV precision than the best current spectrographs provide. A key component in addressing - the limitations of existing instruments is the development of extremely precise calibration light sources that can be used to track drifts and imperfections of the spectrograph, removing them from the science data. A stable, reliable, and relatively - inexpensive calibrator solves a “chicken and egg” problem in the field – motivating the building of more stable spectrographs, secure in the knowledge that they will be able to perform to their potential. Project STABLE_FABRY consists of developing a - novel calibration technique that can be applied to a wide range of high resolution spectrographs. This technique uses a broadband Fabry-Perot etalon to provide the calibration spectrum; the etalon is stabilized by referencing it to an atomic - transition using standard laser spectroscopy methods. Our preliminary work already indicates that a stability of 3 cm/s can be reached with this method, making it precise enough for detection of Earth-like planets. The only other currently available - calibration technology with demonstrated precision at that level is the laser frequency comb, which is an order of magnitude more complex and significantly more expensive. Our technique can easily be adapted to different echelle spectrographs in the - visible and near infrared by simply using an etalon optimized for that particular spectrograph. Developing this concept into an observatory-ready system will present a major breakthrough for high precision spectrographs, enabling detections of Earth - twins with Doppler spectroscopy. - - 2018-04-14, ongoing project - - - 2016-04-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - STABLE_FABRY - - - H2020-MSCA-IF-2014 - - - 659985 - - - - - GOETEBORGS UNIVERSITET - - - EUR 173 857,20 - - - Photocaged Kinase Inhibitors as Molecular Tools for Investigating Neurodegenerative Diseases - - - EUR 173 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - Protein kinases play a critical role in a number of cellular processes, including cell proliferation, differentiation and apoptosis. Recently, the aberrant regulation of lymphocyte-specific protein tyrosine kinases (LCK) has - been associated with the over activation of microglia cells (important immune effector cells that reside in the central nervous system, CNS) and in turn, the development of Alzheimer’s disease (AD). Unfortunately, the detail of LCK's dynamic function - and the importance of quantitative, spatial and time-dependent parameters regarding microglia activation is poorly understood. As such, the ability to manipulate LCK activity using light would result in temporal control of enzymatic activity, thus - serving as a valuable approach to probe the function of LCK in microglia cells and in turn, further our understanding of AD and related neurodegenerative disorders. While such studies cannot be performed using conventional LCK inhibitors, this - project aims to control the enzymatic activity of LCK by the development of a stimuli-responsive release-and-report system, through the introduction of a photolabile 'caging' moiety onto a fluorescent kinase inhibitor. The caging group will also - consist of an appropriate ‘quencher’, quenching the innate fluorescence properties of the inhibitor through energy transfer (FRET). Exposure to light (> 320 nm) will result in decaging of the prodrug to give the active form, while simultaneously - switching ‘on’ the fluorescence — reporting back to the user that the compound has been activated. To demonstrate the potential of the release-and-report kinase inhibitor as a tool to probe LCK function in microglia cells, confocal microscopy will be - employed to visualise the site of microglia activation and the time frame during CNS development in zebrafish model systems. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - PCAGED-KI - - - H2020-MSCA-IF-2016 - - - 745626 - - - - - STICHTING KATHOLIEKE UNIVERSITEIT - STICHTING KATHOLIEKE UNIVERSITEIT - - - EUR 2 000 000 - - - The cell surface tetraspanin web drives tumour development and alters metabolic signalling - - - EUR 2 000 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Cancer development is characterized by uncontrolled proliferation, cell survival and metabolic reprogramming. Tumour cells are surrounded by a fluid-mosaic membrane that contains tetraspanins (Tspans) which are evolutionary - conserved proteins important in the formation of multiprotein complexes at the cell surface (‘tetraspanin web’). Increasing evidence indicates that Tspans are involved in cancer, still the architecture of the Tspan web in native tumour membranes and - its (patho)physiological functions have not been resolved. Based on my preliminary data, I hypothesize that tumour cells contain a disrupted Tspan web in which Tspan interactions are modified leading to aberrant metabolic signalling and tumour - development. This is supported by my discovery that loss of Tspan CD37 leads to spontaneous lymphomagenesis due to activation of the Akt survival pathway. The overall aim of Secret Surface is to unravel the composition, physiological functions and - molecular mechanisms of the Tspan web on tumour development and clinical outcome. To achieve this, I will focus on studying lymphomas using a multidisciplinary approach: I. Detailed analyses of Tspan web composition in lymphoma to select clinically - relevant Tspans (high-throughput tissue microarray technology, multispectral imaging). II. Resolve the endogenous Tspan web on lymphoma cells (super-resolution microscopy), and generation and analysis of lymphoma cells that have a complete deficiency - of multiple Tspans (CRISPR/Cas9 technology). III. Decipher molecular mechanisms underlying Tspan web function in lymphoma cells (membrane organization, membrane-proximal signalling, metabolic reprogramming). With my unique toolbox of Tspan knock-outs - coupled to advanced microscopy and metabolic studies, I expect that Secret Surface will lead to a new concept in cellular physiology in which cell surface organization by the Tspan web drives tumour development, which may open new horizons for the - generation of new cancer therapies. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - Secret Surface - - - ERC-2016-COG - - - 724281 - - - - - GEANT VERENIGING - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH - CESNET ZAJMOVE SDRUZENI PRAVNICKYCH OSOB - CSC-TIETEEN TIETOTEKNIIKAN KESKUS OY - DAASI INTERNATIONAL GMBH - VEREIN ZUR FOERDERUNG EINES DEUTSCHEN FORSCHUNGSNETZES DFN VEREIN E.V. - STICHTING EGI - CONSORTIUM GARR - ETHNIKO DIKTYO EREVNAS TECHNOLOGIAS AE - JISC COLLECTIONS AND JANET LIMITEDLBG - FORSCHUNGSZENTRUM JULICH GMBH - KARLSRUHER INSTITUT FUER TECHNOLOGIE - STICHTING LIBER - MORAVSKA ZEMSKA KNIHOVNA V BRNE - STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN - INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK - GROUPEMENT D INTERET PUBLIC POUR LERESEAU NATIONAL DE TELECOMMUNICATIONS POUR LA TECHNOLOGIE L ENSEIGNEMENT ET LA RECHERCHE - SCIENCE AND TECHNOLOGY FACILITIES COUNCIL - SURFnet bv - SURFSARA BV - - - EUR 2 941 060 - - - Authentication and Authorisation for Research and Collaboration (AARC) - - - EUR 2 950 060 - - - Netherlands - Switzerland - Czech Republic - Finland - Germany - Germany - Netherlands - Italy - Greece - United Kingdom - Germany - Germany - Netherlands - Czech Republic - Netherlands - Poland - France - United Kingdom - Netherlands - Netherlands - - - Other - Research Organisations - Research Organisations - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Other - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Research Organisations - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The goal of AARC is to address technical and functional gaps that prevent the interoperability of existing R&E AAIs. - - - 2017-04-30, closed project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.3."> - - - EINFRA-7-2014 - Provision of core services across e-infrastructures - - - RIA - Research and Innovation action - - - Netherlands - - - AARC - - - H2020-EINFRA-2014-2 - - - 653965 - - - - - TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY - TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY - - - EUR 2 624 517 - - - Advanced holographic optical neural stimulation for vision restoration and basic research - - - EUR 2 624 517 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - When natural sensory input is disrupted, as in outer-retinal degenerative diseases, artificial stimulation of surviving nerve cells offers a potential strategy for bypassing compromised neural circuits and substituting sensory - perception. Current neuro-stimulation interfaces that use electrical currents from micro-electrode arrays are already being clinically applied for retinal stimulation, but their performance is ultimately limited by current spread and the requirement - for physical contact with an implanted device. Future minimally-invasive systems could use light patterns to photo-induce complex yet precise spatio-temporal activity patterns among surviving retinal neurons, with the ultimate potential of restoring - vision to a nearly normal level. - - - 2020-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Israel - - - HoloVision - - - ERC-2014-CoG - - - 648927 - - - - - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - - - EUR 1 896 250 - - - The role of RNA in centromere biology and genome integrity - - - EUR 1 896 250 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - One of the most astonishing processes in the life of a cell is the division into two daughter cells. Such a highly organized process would presumably be regulated tightly by the underlying centromeric DNA sequence; however, - the sites of chromosome attachment to the microtubule spindle are regulated by epigenetic mechanisms. The best-characterized epigenetic mark for centromeres is the histone H3-variant CENP-A, which replaces H3 in some of the nucleosomes within - centromeric chromatin. Centromeres are embedded in pericentromeric heterochromatin and it has become apparent in recent years that heterochromatin is transcribed into non-coding RNAs. We have recently shown that a long non-coding RNA from - pericentromeric heterochromatin of the X chromosome (SATIII) in Drosophila melanogaster localizes in trans to centromeres of all other chromosomes and is an essential component for correct loading and maintenance of CENP-A and, therefore, genome - stability. Additional RNAs in Drosophila and RNAs from other species have been linked to centromeric chromatin, but their function is not understood. We propose that a complex, RNA-based epigenetic mechanism regulates centromere establishment and - function. - - - 2021-06-30, ongoing project - - - 2016-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - cenRNA - - - ERC-2015-CoG - - - 682496 - - - - - THE UNIVERSITY OF BIRMINGHAM - - - EUR 183 454,80 - - - Tracking discoursal shift in news media representation of economic inequality: developing and applying corpus linguistic and critical discourse analysis methods - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - DINEQ explores changes in the discoursal representation of degrees of economic inequality in selected British newspapers in 1971 and 2011. It is the first applied diachronic linguistic study to combine a consideration of the - socio-political history in Britain in those forty years, a comparative analysis of selected public discourses in those two years, and a semantic, grammatical and lexical study of media representations of wealth inequality. The methodological approach - used for this project is primarily Corpus Linguistic, but draws also on Systemic-Functional Grammar, and adopts a broadly Critical Discourse Analytic theory of discourse. The interdisciplinary nature of this project is complemented with the expertise - of the Supervisor, Prof. Michael Toolan, and the Fellow, Dr. Eva Gomez, both experts in Stylistics and Discourse Analysis. The quality of the proposed project is ensured by the commitment of the members involved and the support committed by the - University of Birmingham, one of the leading universities in Europe. This innovative study aims to demonstrate that rigorous and systematic corpus-based discourse analysis can establish discursive change over time, of a kind that is so dispersed and - gradual that it is imperceptible in the day-to-day newspaper-reading of the ordinary reader. - - 2018-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - DINEQ - - - H2020-MSCA-IF-2015 - - - 705247 - - - - - PAUL SCHERRER INSTITUT - PAUL SCHERRER INSTITUT - - - EUR 2 328 648,75 - - - Hyper Quantum Criticality - - - EUR 2 328 648,75 - - - Switzerland - Switzerland - - - Research Organisations - Research Organisations - - Hyper Quantum Criticality – HyperQC is a major initiative with the aim of generating and controlling novel phases of correlated magnetic quantum matter, and of exploring them in high-precision experiments. A combination of new - capabilities enabled by the development of instrumentation, pioneering ultra-fast studies and experiments on magnetic model materials will allow both the exploration of fundamental Hamiltonians and fully quantitative tests of quantum criticality in - hyper-parameter space: temperature, magnetic field, pressure, energy, momentum and time. - - - 2021-11-30, ongoing project - - - 2016-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Switzerland - - - HyperQC - - - ERC-2015-CoG - - - 681654 - - - - - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - - - EUR 2 500 000 - - - Efficient pathways to neutralization and radical production enabled by environment - - - EUR 2 500 000 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The relaxation of electronically excited systems like atoms and molecules embedded in environment is a key question in chemistry and photobiology and the underlying physical mechanisms have been widely studied. The applicant - has predicted theoretically that there are two efficient electronic processes between a system and its neighbors even if the system itself is in its electronic ground state and does not have excess energy, making clear that an important gap exists in - our current understanding of systems embedded in environment. There is extensive future potential in filling this gap and we aim at exploring and exploiting it in systems of physical, chemical, and biological interest. The discovered - electron-transfer mediated decay (ETMD) [several variants of ETMD have been already verified experimentally] and intermolecular Coulombic electron capture (ICEC) mechanisms give rise to a plethora of surprising electronic phenomena relevant to many - fields. In radiation damage, for instance, differently charged cations and electrons are produced by ionization and Auger processes, and ETMD and ICEC continue to be operative, neutralize cations and produce radicals in the environment also after the - known mechanisms of radiation damage have ceased to operate. This leads to severe additional damage. Knowing the factors influencing the impact of ETMD and ICEC most, we can exploit this knowledge to be able to suppress or enhance this impact. Such a - control is invaluable in many cases, may be even in radiation therapy. We are certain that the novel and fundamental ETMD and ICEC processes can be exploited to probe and control systems embedded in an environment. Such a breakthrough necessitates - the advancement of current methodologies far beyond the state-of-the-art, and can only be achieved by the close collaboration of a highly motivated strong team of scientists over a long period of time. The support by the ERC will substantially - contribute to the realization of this vision. - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - ETMD_ICEC - - - ERC-2015-AdG - - - 692657 - - - - - ACADEMISCH ZIEKENHUIS GRONINGEN - OTTO-VON-GUERICKE-UNIVERSITAET MAGDEBURG - Academisch Medisch Centrum bij de Universiteit van Amsterdam - CITY UNIVERSITY OF LONDON - OCUSPECTO OY - IMPLANDATA OPHTALMIC PRODUCTS GMBH - UNIVERSITE CLERMONT AUVERGNE - UNIVERSITE D'AUVERGNE CLERMONT-FERRAND 1 - ECHODIA - - - EUR 3 870 583,92 - - - European Glaucoma Research Training Program-Plus - - - EUR 3 870 583,92 - - - Netherlands - Germany - Netherlands - United Kingdom - Finland - Germany - France - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Glaucoma is the most common age-related neurodegenerative eye-disease in western society and one of the four major blinding eye diseases. If untreated or detected too late, glaucoma will end in blindness, yielding a profound - loss of quality of life for the individual and major costs to society. Given the vast complexity of glaucoma, to advance assessment and therapy beyond the current state-of-the-art, we need a new generation of researchers who are deeply knowledgeable - about and intimately familiar with the many different approaches for study all aspects of glaucoma and the aging visual system: from functional test to anatomy, from gene to ganglion cell, from retina to brain. However, current knowledge is - fragmented and so is the corresponding training. Very few researchers have been adequately trained which severely limits progress. Well-trained teams of dedicated glaucoma researchers are pivotal to integrate and extend the highly specialized - knowledge, and to make a real difference for the patient. - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Netherlands - - - EGRET-Plus - - - H2020-MSCA-ITN-2015 - - - 675033 - - - - - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - - - EUR 159 460,80 - - - Atom-by-Atom Quantum Control of Fermions in Arbitrary Potentials - - - EUR 159 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - The behavior of many-body quantum systems is one of the most difficult problems in modern physics. An interesting and open question is how the properties of a complex many-body system depend on its constituents, and how - collective behavior emerges from the underlying few-particle building blocks. Ultracold atoms offer the unique possibility to realize well-controlled quantum systems and study this question directly in the laboratory. We propose a highly adaptable - approach to assembling systems of few ultracold fermions in optical micro traps. Using a spatial light modulator, we will implement arbitrary trapping potentials and small optical lattices with novel geometries. A near-deterministic loading scheme - will initialize states with extremely low entropies and realize previously inaccessible quantum states. We will perform detailed measurements of static and dynamic spin orderings on small Mott insulating plaquettes and realize unusual cylindrical - optical lattices with periodic boundary conditions. Our approach is complementary to many traditional optical lattice experiments and will generate wide interest in mesoscopic Fermi systems. - - 2018-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Germany - - - FermiTrap - - - H2020-MSCA-IF-2015 - - - 706487 - - - - - PAUL SCHERRER INSTITUT - - - EUR 4 248 000 - - - International, Interdisciplinary and Intersectoral Postdocs - - - EUR 8 496 000 - - - Switzerland - - - Research Organisations - - Large-scale research facilities are enabling cutting edge research and innovation in important domains such as materials science, health and energy. A number of such accelerator facilities is currently under construction in - Europe and will become operational within the next ten years. Thus, there is a growing need for highly qualified researchers trained in interdisciplinary research at such facilities and also an increasing demand from companies to use these facilities - for developing and testing innovative products. - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2015-FP - Marie Skłodowska-Curie Co-funding of regional, national and international programmes (COFUND-FP) - - - MSCA-COFUND-FP - Fellowship programmes - - - Switzerland - - - PSI-FELLOW-II-3i - - - H2020-MSCA-COFUND-2015 - - - 701647 - - - - - CESKE VYSOKE UCENI TECHNICKE V PRAZE - CESKE VYSOKE UCENI TECHNICKE V PRAZE - - - EUR 1 499 500 - - - Artificial Intelligence for Large-Scale Computer-Assisted Reasoning - - - EUR 1 499 500 - - - Czech Republic - Czech Republic - - - Higher or Secondary Education Establishments - Jiri Matas - Tel.: +420 22435721 - Fax: +420 224357385 - Higher or Secondary Education Establishments - Jiri Matas - Tel.: +420 22435721 - Fax: +420 224357385 - - The goal of the AI4REASON project is a breakthrough in what is considered a very hard problem in AI and automation of reasoning, namely the problem of automatically proving theorems in large and complex theories. Such complex - formal theories arise in projects aimed at verification of today's advanced mathematics such as the Formal Proof of the Kepler Conjecture (Flyspeck), verification of software and hardware designs such as the seL4 operating system kernel, and - verification of other advanced systems and technologies on which today's information society critically depends. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Czech Republic - - - AI4REASON - - - ERC-2014-CoG - - - 649043 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSITAET POTSDAM - UNIVERSITEIT VAN AMSTERDAM - - - EUR 1 999 999,33 - - - Monsoons of Asia caused Greenhouse to Icehouse Cooling - - - EUR 1 999 999,33 - - - France - France - Germany - Netherlands - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Unraveling the cause for Cenozoic global climate cooling is one of the most important unresolved questions challenging the Earth and Environmental sciences community today. Increased erosion and weathering of the uplifted - Tibetan Plateau and Himalayas, is advocated as the primary cause for the enigmatic pCO2 drawdown, that led to global cooling 50 to 34 Myrs ago from the warm ice-free Greenhouse world to the bi-polar Icehouse conditions still prevailing today. Asian - Monsoons are genetically linked to high orography associated with the India-Asia collision starting ca. 50 Myrs ago, however, the relation between Greenhouse to Icehouse cooling and Asian Monsoons remains to be explore as they were previously thought - to intensify only much later ca. 25 Myrs ago. Our recent findings of monsoonal activity in Asia since at least 45 Myrs ago raises the fascinating possibility that Asian Monsoons may have triggered global cooling from Greenhouse to Icehouse - conditions. Testing this novel hypothesis and exploring its implications on feedback mechanisms between regional environments, Asian Monsoons and global climate, will constitute the stimulating objectives of MAGIC. 3 PhDs will provide end-member - monsoonal archives well-dated during greenhouse to icehouse cooling from 3 key locations (NE Tibet, SE Asia and Paratethys Sea). These will be analyzed by three postdocs expert in novel proxy methods tailored for MAGIC to infer temperatures, - precipitation, salinity, seasonality, paleoaltimetry, wind-patterns, paleoecology and paleogeography at infra-annual, orbital and tectonic time scales. Ultimately, these records and boundary conditions will be integrated into climate models by a - dedicated postdoc to unravel the role and behavior of Asian Monsoons with respect to long-term Greenhouse to Icehouse cooling, pCO2 levels as well as global hyperthermal and cooling event such as the PETM, MECO and EOT. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - France - - - MAGIC - - - ERC-2014-CoG - - - 649081 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSITAET HAMBURG - UNIVERSITY OF LEEDS - UNIVERSITY OF GLASGOW - FORSCHUNGSZENTRUM JULICH GMBH - CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL - PAUL SCHERRER INSTITUT - - - EUR 3 396 439,10 - - - Magnetic Skyrmions for Future Nanospintronic Devices - - - EUR 3 396 439,60 - - - France - Germany - United Kingdom - United Kingdom - Germany - Germany - Switzerland - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - - Challenges facing technology for power efficient, high density, high speed information processing and storage are well recognised, and strategies for meeting them in the short term define the shape of industry roadmaps. As a - consequence, in the next ten years, radically new approaches will be implemented and will transform how data is stored and manipulated. Skyrmion-based devices are newcomers to this global race for the next generations of information technology. - Skyrmions were discovered in magnetic crystals only a few years ago, but we already have within reach a possibility to create them in nanoscale devices that can be made compatible with conventional integrated circuit technology. Our work in MAGicSky - will substantiate this possibility. - - 2018-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-1-2014 - FET-Open research projects - - - RIA - Research and Innovation action - - - France - - - MAGicSky - - - H2020-FETOPEN-2014-2015-RIA - - - 665095 - - - - - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - - - EUR 1 999 000 - - - Decoding the Lateral Expansion of Plant Stems - - - EUR 1 999 000 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In contrast to animals, in which tissue proliferation in adult individuals is often pathological and deleterious, plants have evolved an indefinite growth habit. A remarkable but under-investigated example is the thickening of - plant stems and roots: It is a purely postembryonic growth process and the group of stem cells responsible – the cambium – is derived from and embedded in fully differentiated tissues. Consequently, lateral plant growth has to integrate and overcome - developmental and physical constraints imposed by participating tissues. This is especially significant in the context of the extracellular matrix, which fixes the position of plant cells relative to each other and provides mechanical support for the - plant body. However, how cells sense and modulate their environment during this process is completely unknown. Here, I will leverage the unique growth mode of plants and explore the process of lateral stem growth in the reference plant Arabidopsis - thaliana as a paradigm for postembryonic growth and tissue remodelling. Thereby I will address the fundamental question of how cell identities are reprogrammed in vivo and how basic cellular functions like interaction between cells and their matrix - contribute to this process. To achieve this I will i) decipher the influence of the extracellular matrix on stem cell activity by cell type-specific modulation of matrix integrity; ii) decode the complex role of brassinosteroid hormones by tuning - their activities during stem cell initiation; iii) record cell fate signatures by high-resolution 4-D expression maps for cambium subdomains; and iv) Identify novel signalling cascades connecting the extracellular matrix with underlying cells by - forward genetics. Together my results will provide unprecedented insight into lateral stem growth – a process responsible for the accumulation of wood and a large proportion of terrestrial biomass and will reveal fundamental concepts of growth - processes in adult organisms. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - PLANTSTEMS - - - ERC-2014-CoG - - - 647148 - - - - - PANTEIO PANEPISTIMIO KOINONIKON KAIPOLITIKON EPISTIMON - - - EUR 164 653,20 - - - Forecasting oil prices, oil price volatility and economic policy uncertainty - - - EUR 164 653,20 - - - Greece - - - Higher or Secondary Education Establishments - - Oil price and oil price volatility forecasts are of major importance, given the oil market is well crowded by participants who proceed to decisions based on these forecasts (e.g. oil traders, monetary policy authorities, etc). - The current state-of-the-art forecasting techniques, though, (i) involve a trade-off among internal consistency, forecasting accuracy and easiness to communicate aspects and (ii) do not use ultra high frequency data. Thus, this exciting and - innovative project aims to develop new econometric model frameworks to forecast oil price and oil price volatility, which will be successful in enhancing internal consistency, forecasting accuracy and easiness to communicate extracting added-value - (in terms of predictability) information from the ultra high sampling frequency. In addition, this project aims to use the forecasted oil price volatility to predict the economic policy uncertainty in Europe, given that oil price shocks exert - significant impact on the effectiveness of economic policy. This project will allow the researcher to advance his existing scientific and transferable skills through the cutting-edge training in the state-of-the-art forecasting techniques, as well - as, in programming, consultancy and policy formulation skills. The outcome of this training (i) will provide the fellow with an invaluable opportunity for the development of a pioneering research agenda and (ii) will position him as an - internationally recognised scholar that contributes to research excellence in Europe. The established capacity of the fellow as an independent researcher in the area of energy economics, the expertise of the scientist-in-charge in state-of-the-art - forecasting techniques and the infrastructure of the host organisation offer great complementarities, which will allow these highly innovative model frameworks to be realised. This project will have a great impact not only to the researcher, but also - to the host organisation and to the European Research Area - - 2017-04-05, closed project | - - - 2015-04-06 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Greece - - - ENEFOR - - - H2020-MSCA-IF-2014 - - - 658494 - - - - - HELSINGIN YLIOPISTO - - - EUR 265 082,40 - - - Formation of nano-scale clusters from atmospheric vapors - - - EUR 265 082,40 - - - Finland - - - Higher or Secondary Education Establishments - - This research concentrates on advancing the understanding of the border between the gas and condensed phase by studying the formation of nanoscale clusters from atmospheric vapours (NanoCAVa). Cluster formation and growth is a - crucial step in forming new aerosol particles in the atmosphere. We aim to resolve the role of molecular clusters in aerosol formation by targeted field measurements at various locations and precisely controlled chamber experiments. Using and further - developing the latest measurement technology, and combining physical and chemical information, enables us to get a full characterization of neutral clusters, which is so far lacking. We utilize the results to create a better description of the - dynamics of 1 – 5 nm nano-particles, which often cannot be treated with traditional theories, and to implement the concept of a cluster mode into the general view on the atmospheric aerosol size distribution. Understanding the factors controlling the - growth of newly formed clusters into climatically relevant particles and cloud condensation nuclei (CCN) enables estimating their importance in the climate system more accurately. This project will facilitate the ER to pursue a successful research - career in atmospheric science and establish her position as an expert of nano-particle measurement technology. It will also strengthen the role of the beneficiary and the partner organization as the leading groups in atmospheric nucleation research - and their mutual collaboration. - - 2018-07-31, ongoing project - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Finland - - - nanoCAVa - - - H2020-MSCA-IF-2014 - - - 656994 - - - - - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - - - EUR 159 460,80 - - - Printed Optoelectronic Devices from Nanosheet Network Electrochemically-gated Field Effect Transistors - - - EUR 159 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - Much research is underway to create a new class of inexpensive electronic devices fabricated by printing combinations of nanomaterial- & functional polymer-inks onto arbitrary substrates, such as everyday plastic film. - This will open a route to a wide range of electronic, optoelectronic & electrochemical applications that are impossible using conventional silicon-based manufacturing approaches. For example, it will enable devices that are mechanically - deformable (i.e. flexible or stretchable), optically transparent, or even cheap enough to be considered disposable. Innovative features such as these will enable electronic functionality to be integrated into locations where they are currently not - feasible. As such, these printed electronics technologies will have applications in many areas of concern for modern society such as public security, healthcare & environmental protection. Here we aim to fabricate aerosol-jet printed ensembles of - semiconductor nanosheets (i.e. nanosheet networks) with controlled composition & morphology, then fabricate these into electrochemically-gated field-effect transistors (E-gated FETs). This will enable the study of electronic transport, charge - separation & recombination processes that occur within these networks with the view to apply them within cheap, printable photodetector & electroluminescent devices. - - 2018-05-15, ongoing project - - - 2016-05-16 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - 2D-EG-FET - - - H2020-MSCA-IF-2015 - - - 707644 - - - - - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - - - EUR 2 390 000 - - - Entanglement Generation in Universal Quantum Dynamics - - - EUR 2 390 000 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - A paradigm example of precise predictions in complex systems is the universal scaling of correlation functions close to phase transitions, with their associated critical exponents. The extension of this concept to time - dependent problems has been studied in the classical regime as well as in the quantum regime. A clean experimental confirmation of this prediction in a quantum system as well as of its connection to non-local entanglement generation is the defined - goal of this project. - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - EntangleGen - - - ERC-2015-AdG - - - 694561 - - - - - DUBLIN CITY UNIVERSITY - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - "NATIONAL CENTER FOR SCIENTIFIC RESEARCH ""DEMOKRITOS""" - CONSIGLIO NAZIONALE DELLE RICERCHE - USTAV ORGANICKE CHEMIE A BIOCHEMIE, AV CR, V.V.I. - ATDBIO LIMITED - BASECLICK GMBH - LIPINUTRAGEN SRL - - - EUR 3 556 990,44 - - - Click Chemistry for Future Gene Therapies to Benefit Citizens, Researchers and Industry - - - EUR 3 556 990,44 - - - Ireland - Germany - United Kingdom - Greece - Italy - Czech Republic - United Kingdom - Germany - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Gene therapy is expected to play a key role in next-generation medicine by correcting the underlying genetic causes of disease, thereby facilitating personalised medicine. Current gene therapy methods possess undesirable side - effects, including insertional mutagenesis, toxicity, low efficiency and off-target cutting. Questions also remain regarding the optimal methods for delivering nucleases into cells and tissues. These limitations will be addressed through the original - and innovative approach of the ClickGene network. - - - 2018-12-31, ongoing project | - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Ireland - - - ClickGene - - - H2020-MSCA-ITN-2014 - - - 642023 - - - - - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - FREIE UNIVERSITAET BERLIN - CONSIGLIO NAZIONALE DELLE RICERCHE - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - TECHNISCHE UNIVERSITAET WIEN - - - EUR 2 000 500 - - - Analog quantum simulators for many-body dynamics - - - EUR 2 000 500 - - - Germany - France - Germany - Italy - Germany - Austria - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Quantum simulators promise to provide unprecedented insights into physical phenomena not accessible with classical computers and have the potential to enable radically new technologies. In this proposal, we argue that analog - dynamical quantum simulators are currently realisable and constitute a most promising class of architectures to fulfil the ultimate promise to devise quantum machines outperforming classical computers. The approach taken is two-pronged: On the one - hand, we devise versatile and practical platforms for dynamical simulators – making use of systems of ultra-cold atoms in optical lattices and the continuum, as well as cavity polaritons. We suggest a concerted and interdisciplinary research - programme of certifying quantum devices and assess them in their computational capabilities, addressing largely unexplored key questions on the power of quantum simulators. On the other, we make use of those devices to probe important questions in - fundamental and applied physics, ranging from technology-relevant problems, concerning transport processes or glassy dynamics, via long-standing challenges in the physics of non-equilibrium and thermalisation phenomena, through puzzles in notions of - quantum turbulence, to questions in the study of quantum gravity. - - 2017-12-31, closed project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.2."> - - - FETPROACT-3-2014 - Quantum simulation - - - RIA - Research and Innovation action - - - Germany - - - AQuS - - - H2020-FETPROACT-2014 - - - 640800 - - - - - "NATIONAL CENTER FOR SCIENTIFIC RESEARCH ""DEMOKRITOS""" - "NATIONAL CENTER FOR SCIENTIFIC RESEARCH ""DEMOKRITOS""" - - - EUR 148 250 - - - A lab-on-chip platform for blood cell counting and identification at the point-of-care - - - EUR 148 250 - - - Greece - Greece - - - Research Organisations - Research Organisations - - Blood cell counting/identification is the most powerful and widespread approach throughout the world for assessing an individual’s health status. The diagnosis and monitoring of an infection (e.g. HIV, malaria, bacterial - infection), the monitor of a chemotherapy outcome (e.g. in cancer patients) or even the diagnosis of rare diseases (e.g. sickle cell disease, non-Hodgkin lymphomas), relies on analysing the number and/or the morphology of different types of blood - cells. Here, we aim to validate a portable, single-cell counting/identification platform that can be used to diagnose and monitor diseases at the point-of-care. The platform consists of a low-cost, handheld, battery-operated, scanner and a disposable - microfluidic biochip. The underlying technology, termed ‘Label-free Cell Identification (L-CI) technology’, is based on the integration of novel, microfabricated components that enable to simultaneously image and count thousands of cells at high - spatial resolution. If successfully commercialized, the L-CI platform will be the first medical instrument to perform a blood cell counting test by the end user at home, in few minutes. The potential is enormous as the L-CI platform will replace - millions of blood cell tests that routinely performed by trained personnel in clinics and hospitals in the developed world but it will also make blood cell tests available in the developing wold. - - 2017-12-31, closed project - - - 2016-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2015 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Greece - - - pocL-CI - - - ERC-2015-PoC - - - 693433 - - - - - ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE - - - EUR 243 934,20 - - - Russia's strategic narrative of the West: A study of influence in Ukraine - - - EUR 243 934,20 - - - United Kingdom - - - Higher or Secondary Education Establishments - - This project investigates the relationship between mass communication and influence in 21st Century international relations. It does so through a study of Russia’s official and media narratives about the West and their - reception in Ukraine. Success in today’s information age is said to depend on ‘whose story wins’. Emerging powers such as Russia have developed various policies and instruments under the banner of ‘soft power’ to challenge Western hegemony in global - media discourse. The projection of counter-hegemonic narratives has been documented extensively, yet we still understand little about their reception and the extent of their influence among target audiences. - - 2018-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - STRATNARRA - - - H2020-MSCA-IF-2014 - - - 654020 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - LEIBNIZ INSTITUT FUER TROPOSPHAERENFORSCHUNG e.V. - IONICON ANALYTIK GMBH - UNIVERSITE D'ORLEANS - - - EUR 1 080 000 - - - MARine atmospheric Science Unravelled: Analytical and mass spectrometric techniques development and application - - - EUR 1 269 000 - - - France - Germany - Austria - France - - - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - MARSU is a collaborative (4 Member States , including one participant from the non-academic sector, and six Third Countries from South America, Africa and Asia) with the goal of gaining new knowledge and reducing the - uncertainty about the effect of aerosols deriving from the air-sea exchange on climate and atmospheric composition connected to air pollution. The results from this key interdisciplinary project will have impact on current and future industrial and - legislative developments. - - 2020-01-31, ongoing project - - - 2016-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - France - - - MARSU - - - H2020-MSCA-RISE-2015 - - - 690958 - - - - - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - - - EUR 147 968 - - - Novel enhancers of functional recovery after stroke - - - EUR 147 968,50 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Several forms of neuroadaptation are controlled by transient increases in the nuclear calcium concentration. Nuclear calcium regulates expression of crucial genes and alterations of this signaling network likely underlie many - neurological disorders. Our work led us to design two innovative strategies exploiting the therapeutic potential of nuclear calcium signaling: 1-developing direct nuclear calcium signaling activators/inhibitors (NCSA/I) and 2-manipulating expression - and/or function of nuclear calcium targets. - - - 2016-08-31, closed project - - - 2015-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2014 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Germany - - - VEGFDANI - - - ERC-2014-PoC - - - 640892 - - - - - NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA - SHAPE IDIOTIKI KEFALAIOUCHIKI ETAIRIA - AMERICAN COMPUTERS AND ENGINEERS HELLAS SA - ECOLE POLYTECHNIQUE - UNIVERSITE PARIS DIDEROT - PARIS 7 - INSTITUT POLYTECHNIQUE DE GRENOBLE - UNIVERSITY OF CYPRUS - GEDIZ UNIVERSITESI - IZMIR INSTITUTE OF TECHNOLOGY - IOPTI - YASAR UNIVERSITESI - EUPRAXIA LIMITED - - - EUR 1 620 000 - - - Optimization Driven Architectural Design of Structures - - - EUR 1 620 000 - - - Greece - Greece - Greece - France - France - France - Cyprus - Turkey - Turkey - France - Turkey - Cyprus - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - "According to UNEP, the building sector is estimated to be worth 10% of the global GDP and employs 111 million people. In addition, buildings use about 40% of global energy, 40% of global resources and emit approximately 33% - of global GHG emissions. Finally, the fact that people today spend, on average, more than 80% of their time indoors, enhances its social importance. All above indicate the necessity to optimize building design. - - 2020-01-31, ongoing project - - - 2016-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Greece - - - OptArch - - - H2020-MSCA-RISE-2015 - - - 689983 - - - - - UNIWERSYTET WARSZAWSKI - UNIWERSYTET WARSZAWSKI - - - EUR 1 768 125 - - - A unified theory of finite-state recognisability - - - EUR 1 768 125 - - - Poland - Poland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Finite-state devices like finite automata and monoids on finite words, or extensions to trees and infinite objects, are fundamental tools of logic in computer science. There are tens of models in the literature, ranging from - finite automata on finite words to weighted automata on infinite trees. Many existing finite-state models share important similarities, like existence of canonical (minimal) devices, or decidability of emptiness, or a logic-automata connection. The - first and primary goal of this project is to systematically investigate these similarities, and create a unified theory of finite-state devices, which: - - 2021-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Poland - - - LIPA - - - ERC-2015-CoG - - - 683080 - - - - - UNIVERSITY OF NEWCASTLE UPON TYNE - ALCYOMICS LTD - RISE ACREO AB - CHR. HANSEN A/S - DANMARKS TEKNISKE UNIVERSITET - FUJIFILM DIOSYNTH BIOTECHNOLOGIES UK LIMITED - LINKOPINGS UNIVERSITET - SANOFI-AVENTIS DEUTSCHLAND GMBH - TECHNISCHE UNIVERSITAET BERLIN - - - EUR 4 038 971,76 - - - Rapid Bioprocess Development - - - EUR 4 038 971,76 - - - United Kingdom - United Kingdom - Sweden - Denmark - Denmark - United Kingdom - Sweden - Germany - Germany - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - Reducing lead times of new medicinal drugs to the market by reducing process development and clinical testing timeframes is a critical driver in increasing European (bio)pharmaceutical industry competitiveness. Despite new - therapeutic principles (e.g. the use of pluripotent stem cells, regenerative medicine and treatments based on personalised medicine or biosimilars) or regulatory initiatives to enable more efficient production, such as Quality by design (QbD) with - associated Process Analytical Technology (PAT) tools , the slow progress in the development of new bioactive compounds still limits the availability of cheap and effective medicines. In addition, the competitiveness of European (bio)pharma industry - is impacted by the unavailability of suitably trained personnel. Fundamental changes in the education of scientists have to be realised to address the need for changes in the traditional ‘big pharma’ business model and the focus on ‘translational - medicine – more early stage clinical trials with patients, more external innovation and more collaboration’ . These changes in education should be based on combining cutting-edge science from the early stage of product development through to - manufacturing with innovation and entrepreneurship as an integral part of the training. The Rapid Bioprocess Development ITN, employing 15 ESRs, brings together industrialist and academic experts with its main aim to address this critical need by - developing an effective training framework in rapid development of novel bioactive molecules from the very early stages of potency and efficacy testing to the biomanufacturing process characterisation and effective monitoring. The main focus of the - research is on oncology related proteins and recombinant proteins to be used in diabetes treatment, although the resulting monitoring and modelling methods will be applicable to other bioactive molecule process development as demonstrated by - validation on a range of relevant bioactives. - - 2018-12-31, ongoing project | - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - Biorapid - - - H2020-MSCA-ITN-2014 - - - 643056 - - - - - FUNDACION BCMATERIALS - BASQUE CENTRE FOR MATERIALS, APPLICATIONS AND NANOSTRUCTURES - "NATIONAL CENTER FOR SCIENTIFIC RESEARCH ""DEMOKRITOS""" - TECHNISCHE UNIVERSITAT DARMSTADT - UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA - AMEN TECHNOLOGIES - - - EUR 580 500 - - - International Network on Advanced high energy Permanent Magnets - - - EUR 580 500 - - - Spain - Greece - Germany - Spain - Greece - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The main objective of this Marie Curie RISE action is to improve and exchange interdisciplinary knowledge of materials design by modelling, materials synthesis, characterization, and materials processing for permanent magnet - development to be able to provide a critical raw free permanent magnet to the industry. Permanent magnets are indispensable for many commercial and military applications. Major commercial applications include the electric, electronic and automobile - industries, communications, information technologies and automatic control engineering. Development and improvement of new technologies based on permanent magnets requires the joint effort of a multidisciplinary researcher collective, involving the - expertise of participants on different disciplines including physics, chemistry, materials science and engineering. A consortium with such expertise is put together to undertake an integrative and concerted effort (via knowledge transfer) to provide - the fundamental innovations and breakthroughs that are needed to fabricate/implement industrially new phases and microstructures required for the development and application of advanced permanent magnets without the use of critical materials. - - 2018-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Spain - - - INAPEM - - - H2020-MSCA-RISE-2015 - - - 691235 - - - - - FORSCHUNGSZENTRUM JULICH GMBH - INTEL DEUTSCHLAND GMBH - BAYERISCHE AKADEMIE DER WISSENSCHAFTEN - BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION - AURORA SRL - MEGWARE COMPUTER VERTRIEB UND SERVICE GMBH - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - EXTOLL GMBH - THE UNIVERSITY OF EDINBURGH - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - KATHOLIEKE UNIVERSITEIT LEUVEN - STICHTING ASTRON, NETHERLANDS INSTITUTE FOR RADIO ASTRONOMY - "ASSOCIATION ""NATIONAL CENTRE FOR SUPERCOMPUTING APPLICATIONS" - NORGES MILJO-OG BIOVITENSKAPLIGE UNIVERSITET - HASKOLI ISLANDS - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH - - - EUR 14 998 342 - - - DEEP - Extreme Scale Technologies - - - EUR 15 873 341,25 - - - Germany - Germany - Germany - Spain - Italy - Germany - Germany - Germany - United Kingdom - Germany - Belgium - Netherlands - Bulgaria - Norway - Iceland - Switzerland - - - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - The DEEP-EST (“DEEP - Extreme Scale Technologies”) project will create a first incarnation of the Modular Supercomputer Architecture (MSA) and demonstrate its benefits. In the spirit of the DEEP and DEEP-ER projects, the MSA - integrates compute modules with different performance characteristics into a single heterogeneous system. Each module is a parallel, clustered system of potentially large size. A federated network connects the module-specific interconnects. MSA - brings substantial benefits for heterogeneous applications/workflows: each part can be run on an exactly matching system, improving time to solution and energy use. This is ideal for supercomputer centres running heterogeneous application mixes - (higher throughput and energy efficiency). It also offers valuable flexibility to the compute providers, allowing the set of modules and their respective size to be tailored to actual usage. - - 2020-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.2."> - - - FETHPC-01-2016 - Co-design of HPC systems and applications - - - RIA - Research and Innovation action - - - Germany - - - DEEP-EST - - - H2020-FETHPC-2016 - - - 754304 - - - - - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - - - EUR 171 460,80 - - - β-Lactams as flaviviral NS3 protease inhibitors - - - EUR 171 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - Flaviviral infections already represent a threat to 2.5 billion people living in tropical and sub-tropical regions. As a consequence of climate change and global warming in the near future these infections are expected to - spread to areas with moderate climate and the possibility of disease outbreak will exist in Europe, especially around the Mediterranean and Adriatic coast, as well as in the United States of America and large parts of Asia. At the moment no medical - treatment against flaviviral diseases is available. Recently, peptide-based compounds which act as flaviviral NS3 protease inhibitors, emerged as potent agents against dengue virus (DENV), Zika virus (ZIKV) and West Nile virus (WNV). These compounds - consist of two to four natural or unnatural amino acids and act by binding to the active site of the protease. Accordingly, the incorporation of an electrophilic warhead, a moiety which would facilitate the covalent binding of the inhibitor to the - catalytic serine residue, into the peptide inhibitor represents a valuable strategy for the improvement of potency of such inhibitors. The goal of the proposed project is to investigate the potential of β-lactams as electrophilic warheads in DENV, - ZIKV and WNV protease inhibitors. For that purpose, new β-lactam derivatives will be synthesized, coupled to peptide inhibitors previously developed by the host group and their affinity to the target will be evaluated by biochemical assays. The most - potent compounds will be characterized in more detail and their activity against dengue virus replication in cell culture, off-target binding, membrane permeability and metabolic stability will be studied. We expect the formation of a covalent bond - between inhibitor and active site of the enzyme to significantly improve inhibitory activity by increasing binding affinity, as well as to ameliorate selectivity and reduce off-target binding. - - 2019-05-01, ongoing project - - - 2017-05-02 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - LIsTEN - - - H2020-MSCA-IF-2016 - - - 748447 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 158 121,60 - - - The role of genome regulation in the origin of animals - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - The goal of this proposal is to understand how animals emerged from their unicellular ancestors. It is clear that the role of the genome regulation at the level of chromatin organization plays a crucial role in cell type - specification, a hallmark of animals. However, how these genome regulatory mechanisms arose and whether they were already present in the unicellular ancestor of animals remains an open question. So far, there is minimal information to address this - question from a comparative point of view. To fill this gap, we will characterize histone modifications, DNA methylation and open chromatin regions in one of the closest unicellular relatives of animals, an ichthyosporean Creolimax fragrantissima, - which exhibits a multicellular-like developmental cycle. In particular, we will carry out a comprehensive genome-wide analysis of histone modifications by ChIP-Seq, ATAC-Seq, as well as techniques for detecting the distribution of 6-methyladenosine - DNA marks, during the developmental cycle. In parallel, we will also investigate the Myc transcription factor network. Myc, along with its partners Max and Mad have been discovered in unicellular holozoans, suggesting that the network has already - regulated cell proliferation and differentiation in the unicellular ancestor of animals. We will detect the genomic targets of Myc, Max and Mad proteins by performing ChIP-Seq. To complement these results with functional studies, we will develop - genome editing tools in Creolimax. The data and the comparative analyses will provide significant insights into the nature of the regulatory genome of the last unicellular ancestor of animals. Specifically, we will learn whether the last unicellular - ancestor already possessed features of complex genome regulation, such as distal enhancers, gene silencing, and dynamic regulation of chromatin states during development, and to what extent the complexity and function of the Myc transcription factor - network was already present. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Spain - - - PREMETAZOAEPIGENOME - - - H2020-MSCA-IF-2016 - - - 747086 - - - - - DUBLIN CITY UNIVERSITY - INSTITUT BARCELONA D ESTUDIS INTERNACIONALS, FUNDACIO PRIVADA - KING'S COLLEGE LONDON - KATHOLIEKE UNIVERSITEIT LEUVEN - UNIWERSYTET WARSZAWSKI - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - KIMMAGE DEVELOPMENT STUDIES CENTRE - - - EUR 3 818 522,52 - - - Explaining Global India: a multi-sectoral PhD training programme analysing the emergence of India as a global actor - - - EUR 3 818 522,52 - - - Ireland - Spain - United Kingdom - Belgium - Poland - Germany - Ireland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - The GLOBAL INDIA ETN will deliver a world-class multi-sectoral doctoral training programme focused on India’s emergence as a global and regional power, and its relationship with the EU. International research on India’s global - role has not kept pace with the changes to India’s status as a growing economy and significant international actor. This is reflected in the lack of PhD level training programmes in Europe that have a focus on India. Europe lacks a knowledge base on - India, the ETN addresses this by creating a multidisciplinary, multi-sectoral network bringing together six leading European universities, with six leading Indian universities, and six non-university partners (one as a beneficiary), all of whom have - previously collaborated together. India's actions as a global actor impact on the interests of the EU, and India as a democratic state could potentially be an ally for the EU on international issues that will affect the welfare and security of - Europe. The quality of Indian democracy also shapes India’s actions as an international actor and therefore this programme examines the domestic challenges that are shaping Indian democracy and the key international actions of India that are most - relevant to its relationship with Europe. The networks training programme is grounded in the academic excellence of the universities and the complimentarily of the strong, diverse range of non-academic partners – a representative business - organisation, a consultancy SME; two think-tanks (in Brussels and New Delhi); a human rights organisation and a global company. The training programme requires that all ESRs will attend 9 network training events, providing workshops on skills - (academic and practitioner), with inputs from all partners; complete an internship with a non-academic partner; and conduct extended period of field-work based in an Indian University. Key measurable outputs of the network will be 30 journal - articles, 60 policy briefs and an active media presence. - - 2021-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Ireland - - - Global India - - - H2020-MSCA-ITN-2016 - - - 722446 - - - - - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - - - EUR 171 460,80 - - - Selective ribosome profiling and biochemistry studies on the co-translational protein folding and assembly in eukaryotic protein synthesis - - - EUR 171 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - Biological activity of cells depends on timely production of natively folded proteins by powerful translation and folding machineries. At a critical regulatory intersection of translation and folding, ribosomes act as - integration hubs coordinating chaperone, enzyme and membrane targeting factor activity, influencing folding. Final assembly of proteins into oligomeric complexes however, has long been considered post-translational and dependent on random collision - of fully synthesized diffusing subunits. In a shift of paradigm, recent evidence from the Bukau laboratory now suggests that in bacteria, assembly initiates co-translationally assisted by chaperones, and gene organization into operons drives - co-localized translation of complex subunits that impacts efficiency of assembly. Fundamental differences in eukaryotes such as rarity of operons and differing chaperone constellations imply a widely different folding and assembly biology, which - remains largely unexplored. The selective ribosome profiling (SeRP) method, developed by the Bukau lab, now allows ground breaking identification and definition of dynamic interactions of nascent chains, at near-residue resolution. Using SeRP with - supporting biochemistry, I will unravel the nascent chain molecular biology underpinning protein folding and assembly in yeast, Saccharomyces cerevisiae, a powerful model for studying the fundamental aspects of this biology. Specifically, I will - establish (1) basic features and prevalence of co-translational protein assembly, (2) how chaperones guide co-translational protein folding to affect assembly. Subunit interaction profiles complemented by chaperone interaction profiles, will expose - the timing and interplay of protein folding and assembly steps linked to protein synthesis, establishing a detailed conceptually new biology of complex assembly in eukaryotes. - - 2020-04-30, Grant Agreement signed - - - 2018-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - srpabsotcpfaaieps - - - H2020-MSCA-IF-2016 - - - 753530 - - - - - "NATIONAL CENTER FOR SCIENTIFIC RESEARCH ""DEMOKRITOS""" - - - EUR 254 871 - - - Seismic Moment and Recurrence (SMR) using Luminescence Dating Techniques - - - EUR 254 871 - - - Greece - - - Research Organisations - - During a seismic-geodynamic process, frictional heating and pressure are generated on sediments fragments resulting in deformation and alteration of minerals contained in them. The luminescence signal enclosed in minerals - crystal lattice can be affected and even zeroed during such an event. This has been breakthrough in geochronological studies as it could be utilized as a chronometer for the previous seismic activity of a tectonically active area. Although the - employment of luminescence dating has in some cases been successfully described, a comprehensive study outlining and defining protocols for routine luminescence dating applied to neotectonic studies has not been forthcoming. This is due to the fact - that the required resetting mechanism of minerals luminescence signal under the influence of friction caused by the relative motion of a fault has been poorly investigated. The proposed project is the experimental investigation, recording and - parameterization of the effects of tectonic phenomena on minerals luminescence signal and the development of detailed protocols for the standardization of the luminescence methodology for directly dating deformed geological formations, so that the - long-term temporal behaviour of seismically active faults could be reasonably understood and modeled. - - 2020-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Greece - - - SMR - - - H2020-MSCA-IF-2016 - - - 743607 - - - - - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - - - EUR 159 460,80 - - - Ubiquitin-dependent regulation of the microtubule cytoskeleton - - - EUR 159 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - The microtubule cytoskeleton is a dynamic array of cylindrical polymers that play important roles in various cellular processes including chromosome segregation and ciliogenesis. Hundreds of accessory factors – grouped under - the term microtubule-associated proteins (MAPs) – orchestrate this network by governing the interaction profile and growth behaviour of microtubules. Due to this critical function, the precise abundance and distribution of MAPs within cells is of - high importance and their deregulation is associated with various human diseases, such as ciliopathies and cancer. Surprisingly little is known about mechanisms involved in the regulation of MAPs and so far only a few of them have been identified as - targets of the major proteolytic control machinery in cells, i.e. ubiquitin-proteasome system. In this work, I will further explore how MAPs are regulated by ubiquitin-dependent degradation by focussing on a multi-subunit ubiquitin E3 ligase called - SCFFbxw5 that seems to play an important role in microtubule control according to preceding experiments of the host lab. Hence, I will investigate in detail two MAPs that were identified as substrates of SCFFbxw5 by the host lab in order to unravel - the functional, temporal, and spatial characteristics of their ubiquitylation by SCFFbxw5. Since these MAPs are known to fulfil crucial functions in ciliogenesis and chromosome segregation, this work will promote our knowledge about how - ubiquitin-dependent degradation contributes to these processes and may open up novel therapeutic strategies with the associated diseases. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - UBIMAPS - - - H2020-MSCA-IF-2016 - - - 748315 - - - - - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - - - EUR 2 272 485 - - - Resolving the molecular mechanisms of intracellular coral-algal symbiosis - - - EUR 2 272 485 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Many cells stably integrate microbes to gain ecological advantages for the organism. A remarkable example is the symbiosis between corals and algae, whose provision of photosynthetically fixed nutrients enables coral survival - in nutrient-poor habitats. To establish symbiosis, coral cells acquire symbionts via phagocytosis, a process often used for pathogen clearance in other animals. Symbionts reside in phagosomes, and the prevailing view is that, similar to some - pathogens, symbionts avoid destruction via phagolysosomal manipulation. Yet, unlike pathogens, symbionts provide nutrients to their host, and this may be key for intracellular persistence. Most research on nutrient translocation has focused on - sugars, but surprisingly, sterols may be significant because cnidarians cannot synthesize cholesterol. However, little is known about the underlying molecular mechanisms of symbiosis establishment. Because corals are intractable cell biological - models, I will leverage our unique resources and expertise to uncover fundamental aspects of symbiont acquisition and metabolic dependence using the emerging model anemone Aiptasia. To investigate symbiont acquisition (Objective 1), I will - distinguish symbiont-phagocytosing cells, test candidate symbiont receptors by gain- and loss-of-function, record symbiont/cell interactions by live-imaging, and generate a symbiosis cell culture system. To understand the significance of - symbiont-derived sterols (Objective 2), I will map cellular sterol utilization and identify the sterol transport machinery, test whether symbiont sterols can functionally substitute cholesterol, identify novel sterol-interacting proteins by pull-down - assays, and explore symbiont persistence mechanisms using comparative phagosome proteomics. This proposal will for the first time provide a mechanistic understanding of coral-algal symbiosis establishment, a crucial process underpinning coral reefs, - economically and ecologically important ecosystems. - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - SYMCELLS - - - ERC-2016-COG - - - 724715 - - - - - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - - - EUR 1 497 931 - - - Revealing the electronic energy landscape of multi-layered (opto)electronic devices - - - EUR 1 497 931 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Modern optoelectronic (OE) devices such as light-emitting or photovoltaic diodes offer exciting opportunities for the future. A wide range of materials has been utilized in these devices, including among others: organic - materials, inorganic quantum dots and hybrid perovskites. While the functionality, performance and device physics vary strongly from material to material and device to device, all OE devices depend on the energy levels of their individual components - and the interaction of the electronic states at the various heterointerfaces. Lacking a method to map the energy levels in a device, energy level diagrams reported for most devices consist of a combination of individual energy levels for each - material, which neglect interactions between the materials (that may cause interfacial dipoles and/or band bending) and do not represent the true energetic landscape. Despite this, they are routinely used for interpretation of device performance and - physics. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - ENERGYMAPS - - - ERC-2016-STG - - - 714067 - - - - - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - - - EUR 1 659 451 - - - Galaxy Evolution in the ALMA Era - The Baryon Cycle and Star Formation in Nearby Galaxies - - - EUR 1 659 451 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - A thorough understanding of the processes regulating the conversion of gas into stars is key to understand structure formation in the universe and the evolution of galaxies through cosmic time. Despite significant progress - over the past years, the properties of the actual dense, star forming gas across normal disk galaxies remain largely unknown. This will be changed with EMPIRE, a comprehensive 500hr large program led by the PI at the IRAM 30m mm-wave telescope. - EMPIRE will provide for the first time extended maps of a suite of dense gas tracers (e.g., HCN, HCO+, HNC) for a sample of nearby, star-forming, disk galaxies. - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - EMPIRE - - - ERC-2016-COG - - - 726384 - - - - - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - - - EUR 1 996 000 - - - Chemically and Thermally Stable Nano-sized Discrete Organic Cage Compounds - - - EUR 1 996 000 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Shape-persistent organic cage compounds consisting only of covalent bonds are fascinating synthetically targets, because they are studied as hosts for the selective recognition of guest molecules, such as artificial lectins, - for catalysis in confined space or for the construction of a new type of porous material. For the latter, the shape-persistency and rigidity of the cage cavity is of utmost importance. There are in principle two existing strategies for the synthesis - of shape-persistent organic cage compounds. Strategy I: A stepwise approach by irreversible reactions. Here, the advantage is the chemical stability of the target compound due to the intrinsic stabilities of the formed bonds. The disadvantage of this - approach is in general the low overall yield, because the system does not allow any ‘self-correction’ of once formed bonds. This is different for the other approach used in Strategy II: By using dynamic covalent bond formation as synthetic tool, - shape-persistent organic cages can be constructed from rather simple molecular building blocks in one step. Here, the yields are usually very high or even quantitatively, because the reversibility of the reaction allows the system to self-correct. - Unfortunately, the resulting compounds are more prone to chemical cleavage of the cages than those synthesized by the irreversible approach. - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - CaTs n DOCs - - - ERC-2016-COG - - - 725765 - - - - - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - - - EUR 1 995 250 - - - Habitability of Oceans and Aqueous Systems on Icy Satellites - - - EUR 1 995 250 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Icy moons in the outer solar system are prime candidates for harbouring alien life within their sub-surface oceans. Among them Enceladus and Europa are considered to have the largest astrobiological potential. Habitat-OASIS - aims to explore the habitability of the ocean worlds of Enceladus, Europa, and other icy satellites using in situ mass spectrometry from on-going and future space missions. At Enceladus (and probably Europa) the ice grains expelled by active plumes - carry matter previously dissolved and suspended in the subsurface oceans, allowing constraining their geochemistry. The mass spectrometers aboard the Cassini-Huygens spacecraft currently orbiting Saturn are analysing this material and already - delivered spectacular science results. Project 1 of this proposal is the refined data analysis of the Enceladus plume material using novel techniques and is the first ever opportunity to explore in detail a potential ocean habitat outside Earth. - Newly developed laser-assisted dispersion experiments will be used to acquire mass spectra on a wide variety of analogue materials, enabling the identification and quantification of inorganic, organic and possibly biogenic compounds embedded in the - ice grains. Geochemical aqueous alteration experiments and numerical modelling will support further constraining the habitability of Enceladus and extrapolating the results to other ocean moons. Project 2 will leverage the laboratory capabilities - from Project 1 to create a comprehensive library of mass spectra in preparation for the upcoming missions visiting Jupiter’s icy moons: ESA’s JUICE Mission and NASA’s Europa Mission. Even if no plume is present both spacecraft will encounter surface - material residing in ejecta clouds around the moons that can be connected to subsurface processes. Having analogue measurements available early in the missions will be critical for exploiting their full potential and will maintain the leading edge of - ocean world exploration in Europe. - - 2022-01-31, ongoing project - - - 2017-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - Habitat-OASIS - - - ERC-2016-COG - - - 724908 - - - - - ERASMUS UNIVERSITEIT ROTTERDAM - ERASMUS UNIVERSITEIT ROTTERDAM - - - EUR 2 000 000 - - - Building EU civil justice: challenges of procedural innovations bridging access to justice - - - EUR 2 000 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Civil justice is under pressure. The proclaimed crisis in civil justice results from the ineffectiveness of procedures in terms of the long duration, high costs, and complexity. These undermine access to justice as guaranteed - by the Human Rights Convention and the EU Charter of Fundamental Rights. It is illustrative in this regard that 26% of the violation judgments concern undue delay of procedure. A well-functioning civil justice system is pivotal for enforcing rights - for consumers and businesses and protecting fundamental rights. Civil justice is also increasingly valued for its contribution to economic growth as seen from the World Bank reports and the EU Justice Agenda for 2020. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - EU-JUSTICE - - - ERC-2016-COG - - - 726032 - - - - - WAGENINGEN UNIVERSITY - WAGENINGEN UNIVERSITY - UNIVERSITEIT UTRECHT - RIJKSUNIVERSITEIT GRONINGEN - - - EUR 2 462 135 - - - Carbonyl Sulphide: new ways of Observing the Climate System - - - EUR 2 462 135 - - - Netherlands - Netherlands - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The future climate of our planet strongly depends on the capacity of the biosphere to sequester atmospheric CO2, and on the abundance of stratospheric sulphate aerosols (SSA). These aerosols form a layer that resides at about - 16 km altitude that, contrary to CO2, has a cooling effect on climate. These two climate-regulating mechanisms are intricately linked to the atmospheric trace gas carbonyl sulphide (COS). - - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Netherlands - - - COS-OCS - - - ERC-2016-ADG - - - 742798 - - - - - FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION - FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION - - - EUR 2 500 000 - - - Writing, reading and managing stress with H3K9me - - - EUR 2 500 000 - - - Switzerland - Switzerland - - - Research Organisations - Research Organisations - - Epigenetic inheritance is the transmission of information, generally in the form of DNA methylation or post-translational modifications on histones that regulate the availability of underlying genetic information for - transcription. RNA itself feeds back to contribute to histone modification. Sequence accessibility is both a matter of folding the chromatin fibre to alter access to recognition motifs, and the local concentration of factors needed for efficient - transcriptional initiation, elongation, termination or mRNA stability. In heterochromatin we find a subset of regulatory factors in carefully balanced concentrations that are maintained in part by the segregation of active and inactive domains. - Histone H3 K9 methylation is key to this compartmentation. - - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Switzerland - - - Epiherigans - - - ERC-2016-ADG - - - 743312 - - - - - BRUNEL UNIVERSITY LONDON - TURKSAT UYDU HABERLESME VE KABLO TV ISLETME AS - DAVID HOLDING AD - LK KNOWLEDGE ENGINEERING LTD - GEBZE TEKNIK UNIVERSITESI - - - EUR 967 500 - - - Sustainable energy demand side management for GREEN Data Centers - - - EUR 967 500 - - - United Kingdom - Turkey - Bulgaria - United Kingdom - Turkey - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - The GREENDC proposal contribute to greener data centres by developing a decision support tool that help data centre managers predict energy demands better and evaluate strategies to minimize energy waste and minimize CO2 - emissions. GREENDC adopt non-linear energy forecasting model and provide a simulation tool based on dynamic simulation model to allow data centre managers conduct what-if analysis considering factors for energy demands and supply. GREENDC is - implemented through knowledge exchange between two academic partners and two industrial partners. Academic partners transfer knowledge on non-linear energy demand forecasting and dynamic simulation to industrial partners while industrial partners - transfer their knowledge on data centre operations through secondment activities. The outcome of the GREENDC activities are expected to reduce CO2 emissions and energy waste due to non-optimised energy load balancing from large number of data centres - across the Europe. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - United Kingdom - - - GREENDC - - - H2020-MSCA-RISE-2016 - - - 734273 - - - - - UNIVERSITE DE NAMUR ASBL - UNIVERSITE DE NAMUR ASBL - - - EUR 1 908 375 - - - Rotifers Highlight the Evolution of Asexuals: the mechanisms of genome evolution in the absence of meiosis - - - EUR 1 908 375 - - - Belgium - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Why sexual reproduction is overwhelmingly predominant among the metazoans remains unclear. Ancient asexual taxa are interesting model systems to gain general insights into the adaptive values of sex. The most notorious and the - highest taxonomic rank within the metazoans to reproduce asexually is the bdelloid rotifers. While studies suggest that most asexuals arose recently, the published genome of the bdelloid rotifer Adineta vaga provided the first positive evidence for - the long-term ameiotic evolution of this group, confirming its ancient asexuality. How bdelloid rotifers have been able to persist despite the expected negative consequences of asexuality is the focus of this ERC proposal. I will study the mechanisms - that prevent genome deterioration and promote diversification in the absence of meiotic recombination. I will include sexual rotifer sister clades in the comparison and study all components of the bdelloid lifestyle that may foster their evolution. - One of the key components could be their desiccation resistance and the associated DNA double-strand breaks that appear upon prolonged desiccation. To this end, I plan to (i) sequence genomes of sexual rotifers and distinct bdelloid species that - diverged a long time ago, including lineages that never experience desiccation; (ii) apply contact genomics, cellular and molecular assays, as well as targeted mutagenesis to uncover their DNA repair mechanisms; (iii) use whole-genome and RAD - sequencing to perform a population genomic study of genetic exchanges among bdelloids; and (iv) investigate the function of the meiosis-specific Spo11 gene in bdelloids through targeted mutagenesis and complementation experiments. Using a - computational simulation I will generate theoretical predictions on the impact of the mechanisms promoting genome evolution in asexuals. This proposal should revolutionize the field of asexual evolution and provide a new biological model system to - study fundamental processes such as DNA repair. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Belgium - - - RHEA - - - ERC-2016-COG - - - 725998 - - - - - Institut du Cerveau et de la Moelle épinière - - - EUR 173 076 - - - Mapping the functional connectome for speed control in spinal motor circuits - - - EUR 173 076 - - - France - - - Research Organisations - - The study of spinal circuits underlying locomotion has a rich history, spanning over 100 years of research. Great efforts have been made to map out the connection patterns between motor neurons and different muscle targets. - Yet, we know little about how premotor networks govern the recruitment of motor neurons and the control of speed. Recent advances in optogenetics, 3D light patterning and fluorescent-targeted patch clamp recordings of identified neurons now enable to - map the functional connectome for speed control in spinal motor circuits. Here we will focus on the role of V2a excitatory premotor interneurons since these cells have the potential to act as a key nexus in the spinal network: i) spanning both in the - hindbrain and spinal cord, ii) making direct connections with motor neurons and iii) modulating locomotor speed. Recent studies revealed piecemeal information related to the V2a to motor neurons connection pattern. By taking advantage of the optical - clarity of the zebrafish larva, we will implement a comprehensive approach combining in vivo electrophysiology, state-of-the-art 3D optical stimulation of genetically targeted cells and functional calcium imaging to resolve the connectivity map of - V2a neurons and answer 3 new key questions: - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - FunCoSpeedSpine - - - H2020-MSCA-IF-2016 - - - 752199 - - - - - UNIVERSITEIT LEIDEN - UNIVERSITEIT LEIDEN - THE UNIVERSITY OF EXETER - - - EUR 1 444 852 - - - Reputation Matters in the Regulatory State: Re-thinking the Fundamentals of Regulatory Independence, Credibility and Accountability - - - EUR 1 444 852 - - - Netherlands - Netherlands - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - RICA will fundamentally challenge, reconceptualise and redefine core foundational assumptions of the regulatory state. Arm’s length governance and regulatory independence have become the cornerstone normative and institutional - design principles of the European regulatory state. Regulatory credibility is premised on agency insulation from politics with major systemic implications in the form of a rise in non-majoritarianism and a parallel devaluation of the political - process. Efforts to compensate through alternative sources of input legitimacy have proven challenging. Conceptualised in a rational-choice tradition, accountability is seen to be in a zero-sum relationship with regulatory autonomy. Bolstering - accountability is said to threaten autonomy, undermining the system’s normative foundations. - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - RICA - - - ERC-2016-STG - - - 716439 - - - - - KOBENHAVNS UNIVERSITET - - - EUR 212 194,80 - - - Wildcat Economics: Informal Mining and Gold from the Global Margins in Contemporary Latin America - - - EUR 212 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - The proposed project will conduct an ethnographic study of small-scale gold mining in South America, otherwise known as ‘wildcat mining’, and aims to explore the interconnection between formal and informal economic spheres at - the global margins. The project will forge a concept of ‘wildcat economics’: that is, the particular form of small-scale mining that takes place in extremely remote regions of the world essentially ‘under the radar’, in this case the Amazonian - rainforest. As such, WILDCAT will explore forms of globalization that do not comprise direct corporate growth, but emerge from individual ventures, and thus challenges stereotypical renditions of resource extraction and global capitalism. Through - this analytical framework, the project provides insights into lesser-understood workings of globalization by offering new ways of conceptualizing the jurisdictions of global capitalism and the economic activities that lie beyond its limits. Fieldwork - will take place in the Madre de Dios region of Peru where wildcat mining activity is clustered, and will draw on methodologies of both anthropology and geography. I will significantly benefit from a placement at the University of Copenhagen as it is - one of the key European centers for the study of Resource Extraction and Management. Significantly, Copenhagen University houses the Centre for Sustainable Artisanal and Small-Scale Mining (SASMin), which explores the activities and issues associated - with small-scale mining around the world. I will be affiliated with this centre as a researcher representing and bringing insights from the discipline of anthropology. - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - WILDCAT - - - H2020-MSCA-IF-2016 - - - 748303 - - - - - Eidgenössische Technische Hochschule Zürich - Eidgenössische Technische Hochschule Zürich - PAUL SCHERRER INSTITUT - - - EUR 149 997 - - - Metal Assisted chemical etching of Gratings for X-ray InterferometriC systems - - - EUR 149 997 - - - Switzerland - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - Phase contrast and scattering-based (dark-field) X-ray imaging can potentially revolutionize the radiological approach to medical imaging because they are intrinsically capable of detecting subtle differences in the electron - density of a material and of measuring the effective integrated local small-angle scattering power generated by the microscopic density fluctuations in the specimen. - - - 2018-04-30, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Switzerland - - - MAGIC - - - ERC-2016-PoC - - - 727246 - - - - - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - - - EUR 1 499 629 - - - Multi-scale Star Formation Across Nascent Galaxies - - - EUR 1 499 629 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - One of the fundamental questions in modern astrophysics is how gas is converted into stars during galaxy formation, and how this may have changed with galactic environment and cosmic time. It is widely accepted that the - unknown physics of star formation (SF) in molecular clouds and feedback from massive stars represent the main uncertainties in our understanding of galaxy formation. The key open questions are: which physical mechanisms govern the time-evolution of - gas towards SF and its subsequent expulsion by feedback? How do these physics change with environment or cosmic time? How did the most extreme stellar systems in the Universe (i.e. globular clusters) form at high redshift? How do the cloud-scale - physics of SF and feedback connect cold dark matter cosmology to the observable galaxy population? It is now possible to answer these questions thanks to two crucial developments. (1) The latest generation of billion-euro observatories allow the - necessary observational data to be taken. (2) The techniques needed to solve the problem have been developed, tested, and validated, through major theoretical efforts that I have led. These developments position me ideally to answer the above - questions with a unique combination of world-leading observational data, fundamental theory, innovative analysis techniques, and state-of-the-art simulations. I will use these to formulate a multi-scale description of SF and feedback, focussing on - the cloud-scale physics and advancing the field beyond the phenomenology of galactic scaling relations. I will introduce an empirically-motivated, physical model for cloud-scale SF and feedback in galaxy formation simulations, thereby overcoming - their main limitation and making the crucial step of linking the observable galaxy population to cold dark matter cosmology. This ambitious programme bridges observations, theory, and simulations, and can only be realised with the human resources - provided by an ERC Starting Grant. - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - MUSTANG - - - ERC-2016-STG - - - 714907 - - - - - RIJKSUNIVERSITEIT GRONINGEN - THE UNIVERSITY OF BIRMINGHAM - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - OULUN YLIOPISTO - CHAMBRE DE COMMERCE ET D'INDUSTRIE DE REGION PARIS ILE-DE-FRANCE - UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II. - ISTITUTO NAZIONALE DI ASTROFISICA - INSTITUTO DE ASTROFISICA DE CANARIAS - UNIVERSITEIT GENT - - - EUR 3 614 425,92 - - - SUrvey Network for Deep Imaging Analysis and Learning - - - EUR 3 614 425,92 - - - Netherlands - United Kingdom - Germany - Finland - France - Italy - Italy - Spain - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - - Though Big Data has become common in many domains nowadays, the challenges to develop efficient and automated mining of the ever increasing data sets by new generations of data scientists are eminent. These challenges span - wide swathes of society, business and research. Astronomers with their high-tech observatories are historically at the forefront of this field, but obviously, the impact in e.g. commercial applications, security, environmental monitoring and - experimental research is immense. We aim to contribute to this general discussion by training a number of young scientists in the fields of computer science and astronomy, focussing on techniques of automated learning from large quantities of data to - answer fundamental questions on the evolution of properties of galaxies. While these techniques will lead to major advances in our understanding of the formation and evolution of galaxies, we will also promote, in collaboration with industry, much - more general applications in society, e.g. in medical imaging or remote sensing. We have put together a team of astronomers and computer scientists, from academic and private sector partners, to develop techniques to detect and classify ultra-faint - galaxies and galaxy remnants in a deep survey of the Fornax cluster, and use the results to study how galaxies evolve in the dense environment of galaxy clusters. With a team of young researchers we will develop novel computer science algorithms - addressing fundamental topics in galaxy formation, such as the huge dark matter fractions inferred by theory, and the lack of detected angular momentum in galaxies. The collaboration is unique - it will develop a platform for deep symbiosis of two - radically different strands of approaches: purely data-driven machine learning and specialist approaches based on techniques developed in astronomy. Young scientists trained with such skills are highly demanded both in research and business. - - 2021-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Netherlands - - - SUNDIAL - - - H2020-MSCA-ITN-2016 - - - 721463 - - - - - KAROLINSKA INSTITUTET - - - EUR 265 059 - - - Identifying the neuronal basis of self-concept in the human medial prefrontal and medial temporal brain regions - - - EUR 265 059 - - - Sweden - - - Higher or Secondary Education Establishments - - Humans have a remarkable ability to construct a complex conceptual representation of their own identity and personality. This self-concept plays a crucial role in everyday life; however, its neurobiological basis remains - unknown. Here, we will use the state-of-the-art method of intracranial electroencephalography (iEEG) to characterize the neuronal representation of self-concept at the level of single-neurons in the medial prefrontal and medial temporal brain - regions. IEEG will be recorded from awake human subjects, which is possible because a subset of neurosurgical patients requires placement of intracranial electrodes to identify the focus of epileptic seizures. We will conduct our studies during this - monitoring time, with no added risk to the patients. Our data will provide unprecedented insights into the neuronal basis of the human self. Our findings will be of great interest to scientists in a broad range of disciplines, including neuroscience, - psychology, artificial intelligence, neurology, psychiatry, as well as to the general public. The supervisors are world-leading experts in the neural self-representation (Prof. Ehrsson) and iEEG (Prof. Fried). Their laboratories conduct excellent - research, as documented by multiple high-impact publications. The host institution (Karolinska Institute) and the partner institution (University of California, Los Angeles) are among the best universities in the world. Together, the fellowship - provides an exceptional opportunity for the experienced researcher to become a leader in his field; he will learn the unique method of iEEG and he will collect the very first data on the neuronal basis of the conceptual self. - - 2021-02-28, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Sweden - - - SELFIEv2.0 - - - H2020-MSCA-IF-2016 - - - 750955 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 999 920 - - - Structure and Function of the Bacterial Transformasome - - - EUR 1 999 920 - - - France - France - - - Research Organisations - Research Organisations - - Natural genetic transformation, first discovered in Streptococcus pneumoniae by Griffith in 1928, is observed in many Gram-negative and Gram-positive bacteria. This process promotes genome plasticity and adaptability. In - particular, it enables many human pathogens such as Streptococcus pneumoniae, Staphylococcus aureus or Neisseria gonorrhoeae to acquire resistance to antibiotics and/or to escape vaccines. For natural transformation to occur, bacteria must develop a - highly regulated physiological state called competence, during which a multiprotein machinery, designated as the transformasome, is specifically expressed. The transformasome drives the uptake of extracellular DNA and its subsequent integration into - the bacterial genome. This intricate system can be divided into three functional entities: the transformation pilus, the DNA entry pore and the recombination apparatus. The architecture and function of the transformasome remains largely elusive. We - propose to dissect the structure and function of this system in the human pathogen Streptococcus pneumoniae. We will combine four complementary approaches to attain our goal: (1) Molecular biology and biochemical studies in vitro (2) Structural - biology on purified proteins or protein complexes using X-ray crystallography and cryo-electron microscopy (3) Structure-function studies in vitro and in vivo (4) Structural biology in situ using cryo-tomography. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - France - - - TransfoPneumo - - - ERC-2016-COG - - - 725554 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 195 454,80 - - - The vision-strike conversion: Neural control of the predatory strike behavior in stomatopods - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Controlling how the body is propelled through space is paramount for survival of most animals. Many species, including humans, use feedback from their visual and proprioceptive systems to correct or confirm body movements. - However, feedback is limited to events that form part of the past. For many high performance behaviors, such as catching a fast incoming ball, the appropriate movement must be 1. anticipated from a short observation period and 2. actuated without - sensory feedback. - - - 2018-07-31, ongoing project - - - 2016-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - EYEPOD - - - H2020-MSCA-IF-2015 - - - 702238 - - - - - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - - - EUR 1 958 101 - - - Quantum State Assembler - - - EUR 1 958 101 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The biggest challenge to using ultracold fermionic atoms to simulate strongly correlated phases is cooling the system to sufficiently low temperatures. The aim of QuStA is to tackle this challenge with a novel bottom-up - approach and assemble many-body systems from individually prepared building blocks. This vision has come within reach through recent breakthroughs in our group in preparing and manipulating few-atom systems with unprecedented fidelity. Building on - this experience, we will prepare multiple such few-atom systems and develop strategies to merge them adiabatically to form a many-body system. - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - QuStA - - - ERC-2016-COG - - - 725636 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 2 492 565 - - - Climate Dynamics of Exoplanets with Condensible Atmospheres - - - EUR 2 492 565 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Condensible substances, which undergo a phase change from gaseous to liquid or solid condensed form, have a profound impact on planetary atmospheres, and are central to the determination of most key aspects of a planet's - climate. The three phases of water operating in Earth's present climate provide the archetype for condensible processes in climate dynamics, but the dawning age of exoplanet discovery and characterization requires that the understanding of phase - change effects be expanded far beyond the situations familiar from the study of Earth's climate, or indeed of the climate of any Solar System planet. The goal of this project is to pioneer the advances needed to understand condensible climate - dynamics for the vastly broader range of condensible substances, thermodynamic and planetary configurations presented by the growing catalogue of exoplanets. The emphasis will be on the smaller range of planets (super-Earth to Earth mass or size - class), which need not have hydrogen-dominated atmospheres and therefore present a richer and highly challenging variety of possible condensible behavior. This class of planets includes all planets that are potentially habitable for Earthlike life, - but even planets that are far from habitable shed light on essential features of planets in the Universe, and will be studied. The work will embrace both small scale buoyancy-driven turbulent convection and planetary scale circulations. Idealized - numerical simulations, buttressed by theoretical analysis will be employed. Particular emphasis will be put on aspects of exoclimate that are amenable to probing by current observations and improved observational techniques likely to become available - in the coming decade. Such properties include cloud properties observable through transit-depth spectra and dayside/nightside temperature and composition contrasts observable through phase curve observations. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - EXOCONDENSE - - - ERC-2016-ADG - - - 740963 - - - - - INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE - - - EUR 185 076 - - - IMPACT OF AROMA AND AROMA INTERACTIONS ON SWEET FLAVOR PERCEPTION IN JUICES AND SOFT BEVERAGES - - - EUR 185 076 - - - France - - - Research Organisations - - In efforts to help consumers improve their health by reducing their consumption of sugar, salt and fat (Europea 2006/1924/EU), the European Commission recently set new standards for the formulation, production, labeling and - advertising of fruit juices (Europea 2012/12/EU). Similar regulations are expected soon for soft drinks. Soft drinks have begun to suffer a poor public image because of their high content of sugar or sugar substitutes, which the beverage industry - uses to counteract or mask undesirable flavors. It may be possible to avoid the need to add sugar to fruit juices and soft drinks if we can identify aroma compounds that help the consumer perceive a drink as sweet. Understanding the interaction - between aromas allow act on sweetness perceived by the consumer and get drinks with less sugar added. - - 2017-05-31, Grant Agreement terminated - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - FLAVODRINKS - - - H2020-MSCA-IF-2014 - - - 655545 - - - - - HERIOT-WATT UNIVERSITY - CENTRE TECNOLOGIC DE TELECOMUNICACIONS DE CATALUNYA - GEORGIA INSTITUTE OF TECHNOLOGY - - - EUR 257 191,20 - - - Inkjet-Printed Wireless Powered Circuits for Sensing and Identification. - - - EUR 269 857,80 - - - United Kingdom - Spain - United States - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - - The project establishes the application of inkjet printing as a key technology for the implementation of batteryless and wireless sensor and communication circuits based on wireless power transfer and energy harvesting, - enabling the realization of the Internet of Things (IoT). Inkjet printing supports a large volume production, achieves a good resolution necessary for high frequency electronics, enables the use of a variety of low cost and flexible materials, and is - a direct-write, and additive manufacturing technology. The research outcomes of the project focus in two goals, 1) demonstrate low profile, conformal, inkjet printed RF energy harvesters and autonomous wireless sensor and communication circuits, and - 2) establish inkjet printing in millimeter wave frequencies. - - - 2019-02-10, Grant Agreement terminated - - - 2016-02-11 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - iREACT - - - H2020-MSCA-IF-2014 - - - 661621 - - - - - UNIVERSITEIT UTRECHT - RIJKSUNIVERSITEIT GRONINGEN - WAGENINGEN UNIVERSITY - UNIVERSITE DE VERSAILLES SAINT-QUENTIN-EN-YVELINES. - EIDGENOSSISCHE MATERIALPRUFUNGS- UND FORSCHUNGSANSTALT - ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE - RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG - AKADEMIA GORNICZO-HUTNICZA IM. STANISLAWA STASZICA W KRAKOWIE - LUNDS UNIVERSITET - - - EUR 3 361 290,84 - - - MEthane goes MObile - MEasurements and MOdelling - - - EUR 3 361 290,84 - - - Netherlands - Netherlands - Netherlands - France - Switzerland - United Kingdom - Germany - Poland - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Mitigation of climate change is a key scientific and societal challenge and also a headline target of the EU2020 strategy. Strong reductions in greenhouse gas emissions are necessary to reach the global warming target agreed - on at the 2015 United Nations Convention of Parties in Paris. Such emission reductions can only be achieved if sources are properly quantified and mitigation efforts are verified, but there are large discrepancies between official emission - inventories and estimates derived from direct measurement of the air. - - 2021-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Netherlands - - - MEMO2 - - - H2020-MSCA-ITN-2016 - - - 722479 - - - - - BAYERISCHE JULIUS-MAXIMILIANS UNIVERSITAT WURZBURG - BAYERISCHE JULIUS-MAXIMILIANS UNIVERSITAT WURZBURG - - - EUR 2 497 567 - - - Four experiments in Topological Superconductivity. - - - EUR 2 497 567 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Topological materials have developed rapidly in recent years, with my previous ERC-AG project 3-TOP playing a major role in this development. While so far no bulk topological superconductor has been unambiguously demonstrated, - their properties can be studied in a very flexible manner by inducing superconductivity through the proximity effect into the surface or edge states of a topological insulator. In 4-TOPS we will explore the possibilities of this approach in full, and - conduct a thorough study of induced superconductivity in both two and three dimensional HgTe based topological insulators. The 4 avenues we will follow are: - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - 4-TOPS - - - ERC-2016-ADG - - - 741734 - - - - - UNIVERSITY OF BRADFORD - UNIVERSITY OF BRADFORD - THE UNIVERSITY OF WARWICK - THE UNIVERSITY OF BIRMINGHAM - THE UNIVERSITY OF NOTTINGHAM - THE UNIVERSITY OF NOTTINGHAM NINGBO - - - EUR 2 497 843 - - - Europe’s Lost Frontiers: exploring climate change, settlement and colonisation of the submerged landscapes of the North Sea basin using ancient DNA, seismic mapping and complex systems modelling - - - EUR 2 497 843 - - - United Kingdom - United Kingdom - United Kingdom - United Kingdom - United Kingdom - China - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The only lands on Earth that have not been explored in any depth by science are those that have been lost to the oceans. Global warming at the end of the last Ice Age led to the inundation of vast landscapes that had once been - home to thousands of people. These lost lands hold a unique and largely unexplored record of settlement and colonisation linked to climate change over millennia. Amongst the most significant is Doggerland. - - - 2020-11-30, ongoing project - - - 2015-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - Lost Frontiers - - - ERC-2014-ADG - - - 670518 - - - - - CONSIGLIO NAZIONALE DELLE RICERCHE - PARIS-LODRON-UNIVERSITAT SALZBURG - UNIVERSITA DEGLI STUDI DI GENOVA - MIKROBIOLOGICKY USTAV - AVCR, V.V.I. - EBERHARD KARLS UNIVERSITAET TUEBINGEN - UNIVERZA V LJUBLJANI - CARDIFF UNIVERSITY - NATURAL ENVIRONMENT RESEARCH COUNCIL - AvantiCell Science Ltd - FUNDACIO INSTITUT CATALA DE NANOCIENCIA I NANOTECNOLOGIA - - - EUR 2 814 491,16 - - - Probing safety of nano-objects by defining immune responses of environmental organisms - - - EUR 2 814 491,16 - - - Italy - Austria - Italy - Czech Republic - Germany - Slovenia - United Kingdom - United Kingdom - United Kingdom - Spain - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - - PANDORA (Probing safety of nano-objects by defining immune responses of environmental organisms) shall assess the global impact of engineered nanoparticles (NP) on the immune responses of representative organisms covering all - evolutionary stages and hierarchical levels from plants to invertebrates and vertebrates. Immunity is a major determinant of the survival and fitness of all living organisms, therefore immunosafety of engineered NP is a key element of environmental - nanosafety. PANDORA will tackle the issue of global immunological nanosafety by comparing the impact of widely-used NP (e.g., iron, titanium and cerium oxide) on the human immune response with their effects in representative terrestrial and marine - organisms. This comparison will focus on the conserved system of innate immunity/stress response/inflammation, aiming to identify common mechanisms and markers across immune defence evolution shared by plants (Arabidopsis), invertebrate (bivalves, - echinoderms, earthworms), and vertebrate (human) species. - - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Italy - - - PANDORA - - - H2020-MSCA-ITN-2015 - - - 671881 - - - - - KARLSRUHER INSTITUT FUER TECHNOLOGIE - INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE TOULOUSE INSAT - ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA - PANEPISTIMIO THESSALIAS - UNIVERSITE D'AIX MARSEILLE - UNIVERSITY OF LIMERICK - Institute of Mechanics, Bulgarian Academy of Sciences - MITIS - Alcatel Lucent Ireland Limited - IN'AIR SOLUTIONS - - - EUR 3 815 117,07 - - - Research and training network on MIniaturized Gas flow for Applications with enhanced Thermal Effects - - - EUR 3 815 117,07 - - - Germany - France - Italy - Greece - France - Ireland - Bulgaria - Belgium - Ireland - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Depletion of natural resources combined with the extending footprint of mankind has led to a shift in importance of research and development topics. In the 1970s and 1980s process yield was primarily targeted, but emphasis is - now focussed on resource efficiency as a primary objective. Routes for resource efficiency have to be identified and implemented to provide a more environmental and resource-oriented technology in near future. - - - 2019-10-31, ongoing project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - MIGRATE - - - H2020-MSCA-ITN-2014 - - - 643095 - - - - - ISTITUTO NAZIONALE DI ASTROFISICA - REGENTS OF UNIVERSITY OF MINNESOTA - - - EUR 244 269 - - - Cosmological simulations of radio bright plasmas - - - EUR 244 269 - - - Italy - United States - - - Research Organisations - Higher or Secondary Education Establishments - - Merging galaxy clusters are among the most energetic events in the Universe. Their interaction generates shocks and turbulence in the ionised cluster medium, driving the amplification of magnetic fields and the acceleration of - relativistic particles. This leads to the formation of large diffuse radio sources in some clusters. The next generation of radio telescopes, including the European LOFAR observatory, will revolutionize the field, unveiling a complex picture of these - non-thermal processes in clusters. However we still lack numerical simulations to match the capabilities of these instruments. This roots in the complexity of models for MHD-turbulence and cosmic-rays poses challenging demands to simulators. Only - recent advances in implementations at the outgoing host and by the applicant make these simulations now feasible. - - 2018-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Italy - - - Cosmo Plasmas - - - H2020-MSCA-IF-2014 - - - 658912 - - - - - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - STICHTING KATHOLIEKE UNIVERSITEIT - ROCHE DIAGNOSTICS GMBH - THE NOTTINGHAM TRENT UNIVERSITY - ISTITUTO EUROPEO DI ONCOLOGIA SRL - MEDIZINISCHE UNIVERSITAT INNSBRUCK - FUNDACION CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III - REGION HOVEDSTADEN - INSTITUT GUSTAVE ROUSSY - - - EUR 3 627 525,24 - - - Training Network for the Immunotherapy of Cancer - - - EUR 3 627 525,24 - - - Germany - Netherlands - Germany - United Kingdom - Italy - Austria - Spain - Denmark - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - - In the European Union, cancer is the leading cause of death and the overall cancer incidence is still increasing. As a result of expanding efforts to improve cancer outcome, a main paradigm change is occurring in cancer - therapy towards individualized medicine. Antibody-based therapies form an integral and constantly growing part of this approach. Antibody-based therapies will strongly influence the coming decade of cancer care. The importance of immunotherapy has - been highlighted by the prestigious Science journal as “breakthrough of the year 2013”, heralding the rising importance of immunotherapy. Accordingly the need for well-trained and skilled researchers in academia and industry is dramatically - increasing in this field. IMMUTRAIN is a training network bringing together experts in the fields of monoclonal antibodies, dendritic cells, T-cells and immunomodulatory nucleic acids with a considerable industrial involvement. The network comprises - nine academic research groups and five industrial partners in a total of seven European countries. IMMUTRAIN will actively create synergies between those sectors by forming and promoting young researchers to match the challenges of immunotherapies. - Particular focus will be placed on combinatorial therapies and on the new emerging field of bispecific antibodies used to target both the tumor and the patient´s immune system. Fifteen Ph. D. students (early stage researchers, ESR) reinforced by the - project leaders will investigate innovative therapeutic strategies and provide the rationale for future clinical trials. Throughout their projects, ESR will learn to integrate academic and industrial aspects and will sharpen their experimental and - complementary skills in a well-designed and diversified training program. - - 2019-11-30, ongoing project - - - 2015-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - IMMUTRAIN - - - H2020-MSCA-ITN-2014 - - - 641549 - - - - - EOTVOS LORAND TUDOMANYEGYETEM - EOTVOS LORAND TUDOMANYEGYETEM - - - EUR 1 511 436 - - - Astrophysical Dynamics and Statistical Physics of Galactic Nuclei - - - EUR 1 511 436 - - - Hungary - Hungary - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - We address some of the major unsolved questions of galactic nuclei using methods of condensed matter physics. Galactic nuclei host a central supermassive black hole, a dense population of stars and compact objects, and in many - cases a bright gaseous disk feeding the supermassive black hole. The observed stellar distribution exhibits both spherical and counterrotating disk-like structures. Existing theoretical models cannot convincingly explain the origin of the stellar - disks. Is there also a “dark cusp” or “dark disk” of stellar mass black holes? Are there intermediate mass black holes in the Galactic center? We examine the statistical physics of galactic nuclei and their long term dynamical evolution. A star - orbiting a supermassive black hole on an eccentric precessing orbit covers an axisymmetric annulus. The long-term gravitational interaction between such annuli is similar to the Coulomb interaction between axisymmetric molecules constituting a liquid - crystal. We apply standard methods of condensed matter physics to examine these astrophysical systems. The observed disk and spherical structures represent isotropic-nematic phase transitions. We derive the phase space distribution and time-evolution - of different stellar components including a population of black holes. Further, we investigate the interaction of a stellar cluster with a gaseous disk, if present. This leads to the formation of gaps, warps, and spiral waves in the disk, the - redistribution of stellar objects, and possibly the formation of intermediate mass black holes. We explore the implications for electromagnetic and gravitational wave observatories. Dark disks of black holes could provide the most frequent source of - gravitational waves for LIGO and VIRGO. These detectors will open a new window on the Universe; the proposed project will open a new field in gravitational wave astrophysics to interpret the sources. We also explore implications for electromagnetic - observations. - - 2020-07-31, ongoing project - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Hungary - - - GalNUC - - - ERC-2014-STG - - - 638435 - - - - - HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH - INFRAFRONTIER GMBH - CENTRE EUROPEEN DE RECHERCHE EN BIOLOGIE ET MEDECINE - MEDICAL RESEARCH COUNCIL - USTAV MOLEKULARNI GENETIKY AKADEMIE VED CESKE REPUBLIKY VEREJNA VYZKUMNA INSTITUCE - Toronto Centre for Phenogenomics Inc. - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - GENOME RESEARCH LIMITED - CONSIGLIO NAZIONALE DELLE RICERCHE - UNIVERSITAT AUTONOMA DE BARCELONA - EUROPEAN MOLECULAR BIOLOGY LABORATORY - - - EUR 1 103 613,75 - - - Research Infrastructures for Phenotyping, Archiving and Distribution of Mouse Disease Models - Promoting International Cooperation and User Engagement to Enhance Biomedical Innovation - - - EUR 1 109 863,75 - - - Germany - Germany - France - United Kingdom - Czech Republic - Canada - Spain - United Kingdom - Italy - Spain - Germany - - - Research Organisations - Other - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The IPAD-MD project addresses cooperation and coordination between the pan-European INFRAFRONTIER Research Infrastructure and complementary research infrastructures in America, Asia and Australia, contributing to the global - effort of the International Mouse Phenotyping Consortium (IMPC). In order to increase the reach of INFRAFRONTIER, IPAD-MD will also reach out to complementary infrastructures and user communities in Africa. - - - 2019-05-31, ongoing project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.3.2."> - - - INFRASUPP-6-2014 - International cooperation for research infrastructures - - - CSA - Coordination and support action - - - Germany - - - IPAD-MD - - - H2020-INFRASUPP-2014-2 - - - 653961 - - - - - BIOBANKS AND BIOMOLECULAR RESOURCES RESEARCH INFRASTRUCTURE CONSORTIUM (BBMRI-ERIC) - EUROPEAN MOLECULAR BIOLOGY LABORATORY - MEDIZINISCHE UNIVERSITAET WIEN - INFRAFRONTIER GMBH - EATRIS ERIC - ECRIN EUROPEAN CLINICAL RESEARCH INFRASTRUCTURE NETWORK - UNIVERSIDADE DO MINHO - USTAV MOLEKULARNI GENETIKY AKADEMIE VED CESKE REPUBLIKY VEREJNA VYZKUMNA INSTITUCE - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - EUROPEAN RESEARCH INFRASTRUCTURE CONSORTIUM FOR THE SURVEY OF HEALTH, AGEING AND RETIREMENT IN EUROPE - - - EUR 1 995 633,75 - - - Reseach Infrastructures Training Programme - - - EUR 1 995 633,75 - - - Austria - Germany - Austria - Germany - Netherlands - France - Portugal - Czech Republic - United Kingdom - Italy - France - Germany - - - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Other - Research Organisations - Other - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - - There has never been a greater need for skilled managers and operators of research infrastructure (RI). Europe must develop the workforce that will turn ~50 nascent RIs with sites in different countries into powerhouses of - support for major projects comparable to understanding the blueprint of life or discovering new subatomic particles. RItrain will develop a flagship training programme enabling RIs across all domains to gain expertise on governance, organisation, - financial and staff management, funding, IP, service provision and outreach in an international context. It will be designed and delivered by experts who have set up and managed RIs from concept to maturity. We will define competencies required by - RIs through consultation with their senior managers. The resulting competency framework will underpin a Bologna-compliant degree, the Master in Research Infrastructure Management, with three delivery routes. (1) Professionals working in RIs (or - organisations representing them) can dip into the content, focusing on areas where there is most need. (2) Management teams can take the course as an organisation, dividing modules between them to gain a certificate for the RI. This will flag the RI - as an organisation that values staff development, improving its attractiveness as an employer. (3) Recent graduates and others wishing to enhance their employability can take a full master’s degree. Course content will include webinars led by senior - managers of RIs. A staff-exchange programme will catalyse exchange of best practice and foster cooperation to develop a mobile work force effective across many RIs. By the end of the project we will be delivering a master’s curriculum funded through - course fees. Others with an interest in adopting it will be encouraged to do so, providing a means of expanding the programme. Europe’s research community and global collaborators will gain from world-class facilities to support excellent, - high-impact research to benefit humankind. - - 2019-08-31, ongoing project | - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.2.2."> - - - INFRASUPP-3-2014 - Strengthening the human capital of research infrastructures - - - CSA - Coordination and support action - - - Austria - - - RItrain - - - H2020-INFRASUPP-2014-2 - - - 654156 - - - - - EBERHARD KARLS UNIVERSITAET TUEBINGEN - EBERHARD KARLS UNIVERSITAET TUEBINGEN - - - EUR 1 498 353 - - - From the origin of Earth's volatiles to atmospheric oxygenation - - - EUR 1 498 353 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Aim of this project is to understand the connection between endogenic and exogenic processes of our planet that led to the redox contrast between Earth’s surface and interior. For this purpose the time constraints on - atmospheric oxygenation can be refined and for the first time linked with a new approach to Earth’s endogenic processes like plate tectonics, mantle melting, volcanism, continent formation and subduction-related sediment- and crust recycling. These - objectives will be achieved by using the unique geochemical capabilities of the selenium (Se) isotope system to unlock the geological record of changing oxygen fugacities in the mantle-crust-atmosphere reservoirs. The power of the Se isotope system - lies in its redox sensitivity and in the volatile and highly siderophile/chalcophile character of elemental Se. This links Se to the evolution of other volatiles during key geological processes from Earth formation ca. 4.5 Ga ago until today. The - occurrence and behavior of Se is fully controlled by accessory micrometric sulfide minerals in the silicate Earth, which may conserve their original Se isotopic signatures over large geological timescales and can be dated via the 187Re-187Os - geochronometer. This offers high resolutions in time and space that are groundbreaking for research on Earth System Oxygenation. Covering Earth geologic history, new high-precision Se isotope data of the sedimentary and representative mantle-derived - magmatic rock record from all major plate tectonic settings will be combined with the mineral-scale record of robust and global “time capsules” such as diamond inclusions. Once the evolution into todays dynamic Earth’s Redox System is understood, the - investigation will be pushed back in time to Earth’s formation. This involves a reconciliation of the meteoritic and Archean rock and mineral-scale Se isotope record to constrain the origin of volatiles essential for the oceans, generation of an - atmosphere and development of life on our planet. - - 2020-02-29, ongoing project - - - 2015-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - O2RIGIN - - - ERC-2014-STG - - - 636808 - - - - - EBERHARD KARLS UNIVERSITAET TUEBINGEN - UNIVERSIDAD DE MURCIA - KUNGLIGA TEKNISKA HOEGSKOLAN - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN - CARL ZEISS VISION INTERNATIONAL GMBH - VOPTICA S.L. - - - EUR 3 544 115,04 - - - Myopia: Fundamental understanding needed - - - EUR 3 544 115,04 - - - Germany - Spain - Sweden - Spain - Ireland - Germany - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The proposed ETN “Myopia: fundamental understanding needed” (MyFUN) provides an international, interdisciplinary platform to train young scientists at the interface of physics and biology, to study unresolved questions about - the visual control of eye growth. It has been extensively documented that the growth of the eye is controlled by closed-loop visual feedback, using retinal image defocus as an error signal. However, with tense education, predominant indoor activity - and extensive near work, the eyes of young people grow too long and become near-sighted (myopic), reaching a prevalence of 95% in some Asian cities and 50% at German universities. While myopia is clearly a civilization disorder, it is strikingly - unclear by which visual stimuli it is triggered, and how it can be stopped. Emerging optical interventions have still only moderate effects. There are fundamental questions, like “Why does myopia not limit itself?”, “Why does undercorrection not - reduce its progression?”, “Why are the effects of new spectacle designs to inhibit myopia so small?”, “What determines when it starts and can we find biological markers to predict myopia in individual cases?”. We propose a scheme of novel - experiments, divided into 14 research projects that all have sufficient scientific depth and merit to merge into 14 successful PhD theses. The answers to the research questions will fundamentally improve our understanding of myopia, will be - recognized worldwide and will represent a major contribution of the European Community to the global problem of the rising incidence of myopia. Our consortium consists of 7 Beneficiaries, combining the expertise of 5 academic partners with excellent - research and teaching records and 2 fully integrated private sector partners. MyFUN will be supported by a management team experienced in multi-site training activities and counselled by a scientifically accomplished External Advisory Board. - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - MyFUN - - - H2020-MSCA-ITN-2015 - - - 675137 - - - - - USTAV MOLEKULARNI GENETIKY AKADEMIE VED CESKE REPUBLIKY VEREJNA VYZKUMNA INSTITUCE - USTAV MOLEKULARNI GENETIKY AKADEMIE VED CESKE REPUBLIKY VEREJNA VYZKUMNA INSTITUCE - SLOVENSKA ZDRAVOTNICKA UNIVERZITA V BRATISLAVE - - - EUR 1 950 000 - - - Dicer-Dependent Defense in Mammals - - - EUR 1 950 000 - - - Czech Republic - Czech Republic - Slovakia - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - - Viral infection or retrotransposon expansion in the genome often result in production of double-stranded RNA (dsRNA). dsRNA can be intercepted by RNase III Dicer acting in the RNA interference (RNAi) pathway, an ancient - eukaryotic defense mechanism. Notably, endogenous mammalian RNAi appears dormant while its common and unique physiological roles remain poorly understood. A factor underlying mammalian RNAi dormancy is inefficient processing of dsRNA by the - full-length Dicer. Yet, a simple truncation of Dicer leads to hyperactive RNAi, which is naturally present in mouse oocytes. - - 2020-06-30, ongoing project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Czech Republic - - - D-FENS - - - ERC-2014-CoG - - - 647403 - - - - - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - EBERHARD KARLS UNIVERSITAET TUEBINGEN - - - EUR 1 499 125 - - - Transformations of Food in the Eastern Mediterranean Late Bronze Age - - - EUR 1 499 125 - - - Germany - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Mediterranean cuisine has long been perceived as a timeless constant, already linking the different societies around the sea by the 2nd mill. BC. The geographic frame was considered to be essential, whereas intercultural - entanglements as transformative factors were neglected. By integrating archaeological, textual and scientific research, we will shed new light on the transformative power of cultural encounters arising from the intense connectivity between local - communities in the Eastern Mediterranean Late Bronze Age and the simultaneous introduction of food of South and East Asian origin (e.g. pepper, nutmeg, cinnamon). We intend to achieve this goal by analysing human remains and pottery vessels from - selected sites between the Aegean and Egypt from the 15th to the 12th cent. BC to trace spatial and temporal dynamics. Organic residue analyses of the pottery will shed light on the preparation and consumption of food (e.g. oils, wine, spices). We - will include vessels with their contents labelled on them and then link so-far hardly understood Egyptian textual evidence to the contents, which enables a new understanding of these texts for the study of food. We combine the results from residue - analyses with a cutting-edge approach to the study of human dental calculus, the potential of which has just been recognized for the understanding of human nutrition: we will analyse DNA from food traces and bacteria as well as proteins, lipids and - microremains in dental calculus. This will give unique insight into individual consumption of different oils (olive, sesame etc.), kinds of milk (cow, sheep, goat) and related products (cheese, kefir) and of plants (spices, cereals), which goes far - beyond what has been achieved to date. The linkage of food residues in vessels and calculus will allow us to trace processes of homogenization and diversification as consequences of early globalization and better understand food circulation in - present and future globalization processes. - - 2021-06-30, ongoing project - - - 2016-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - FoodTransforms - - - ERC-2015-STG - - - 678901 - - - - - NATIONAL OBSERVATORY OF ATHENS - - - EUR 152 653,20 - - - Cyclone processes leading to extreme rainfall in the Mediterranean region - - - EUR 152 653,20 - - - Greece - - - Research Organisations - - Mediterranean cyclones are among the most important natural hazards in the region, affecting more than 135 million people. The physical mechanisms that make Mediterranean cyclones evolve into severe storms are not yet fully - understood due to many uncertainties in the underlying atmospheric processes. These processes are mainly associated with deep convection and air-sea interactions at meso-scales, as well as with large-scale atmospheric systems that affect the region. - The scientific objective of the project is to show how these processes lead to extreme rainfall in the Mediterranean and contribute to the better forecasting of cyclones induced extreme rainfall. - - 2018-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Greece - - - ExMeCy - - - H2020-MSCA-IF-2014 - - - 658997 - - - - - KOBENHAVNS UNIVERSITET - KOBENHAVNS UNIVERSITET - REGION HOVEDSTADEN - - - EUR 2 500 000 - - - Reaching the effects of gastric bypass on diabetes and obesity without surgery - - - EUR 2 500 000 - - - Denmark - Denmark - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Gastric bypass surgery results in massive weight loss and diabetes remission. The effect is superior to intensive medical treatment, showing that there are mechanisms within the body that can cure diabetes and obesity. - Revealing the nature of these mechanisms could lead to new, cost-efficient, similarly effective, non-invasive treatments of these conditions. The hypothesis is that hyper-secretion of a number of gut hormones mediates the effect of surgery, as - indicated by a series of our recent studies, demonstrating that hypersecretion of GLP-1, a hormone discovered in my laboratory and basis for the antidiabetic medication of millions of patients, is essential for the improved insulin secretion and - glucose tolerance. But what are the mechanisms behind the up to 30-fold elevations in secretion of these hormones following surgery? Constantly with a translational scope, all elements involved in these responses will be addressed in this project, - from detailed analysis of food items responsible for hormone secretion, to identification of the responsible regions of the gut, and to the molecular mechanisms leading to hypersecretion. Novel approaches for studies of human gut hormone secreting - cells, including specific expression analysis, are combined with our advanced and unique isolated perfused gut preparations, the only tool that can provide physiologically relevant results with a translational potential regarding regulation of - hormone secretion in the gut. This will lead to further groundbreaking experimental attempts to mimic and engage the identified mechanisms, creating similar hypersecretion and obtaining similar improvements as the operations in patients with obesity - and diabetes. Based on our profound knowledge of gut hormone biology accumulated through decades of intensive and successful research and our successful elucidation of the antidiabetic actions of gastric bypass surgery, we are in a unique position to - reach this ambitious goal. - - 2021-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Denmark - - - BYPASSWITHOUTSURGERY - - - ERC-2015-AdG - - - 695069 - - - - - EBERHARD KARLS UNIVERSITAET TUEBINGEN - EBERHARD KARLS UNIVERSITAET TUEBINGEN - - - EUR 1 808 200 - - - Site-directed RNA Editing to Manipulate RNA and Protein Function - - - EUR 1 808 200 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Enzymatically active RNA-guided proteins, like the RNA-induced silencing complex (RISC), are particularly versatile tools for the rationally programmed manipulation of genetic information. After successful re-addressing of - various natural RNA-guided machineries it is now time to tackle the engineering of novel, user-defined tools. With this respect we have recently achieved the engineering of an RNA-guided adenosine-to-inosine RNA editing machinery. Since inosine is - biochemically read as guanosine, A-to-I editing alters genomic information on the RNA-level and may potentially allow for the manipulation of RNA processing or protein function. We have already achieved to apply our RNA editing approach for the - repair of several missense and nonsense point mutations on reporter and disease-related genes in vitro and demonstrated its applicability in mammalian cell culture. - - 2020-07-31, ongoing project - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - RNArepair - - - ERC-2014-CoG - - - 647328 - - - - - STARLAB BARCELONA SL - Forschungsgesellschaft für Arbeitsphysiologie und Arbeitsschutz e.V. - UNIVERSITE DE LIEGE - UNIVERSITA DEGLI STUDI DI MILANO - EBERHARD KARLS UNIVERSITAET TUEBINGEN - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH - - - EUR 3 925 588,50 - - - Studying, Measuring and Altering Consciousness through information theory in the electrical brain - - - EUR 3 925 588,75 - - - Spain - Germany - Belgium - Italy - Germany - France - United Kingdom - Germany - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - - What is consciousness? Can it be measured? While humankind has struggled with these questions for millennia, our project will focus on more modest but nonetheless ambitious and related goals. Inspired by recent developments in - neuroscience and the potential role of fundamental concepts such as information integration and algorithmic complexity, we will study, model, quantify, and alter observable aspects of consciousness. Our vision is that consciousness will someday be - electromagnetically measured and altered, and that the associated needed insights will prove crucial to the development cognitive sciences. - - - 2019-08-31, ongoing project | - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-1-2014 - FET-Open research projects - - - RIA - Research and Innovation action - - - Spain - - - LUMINOUS - - - H2020-FETOPEN-2014-2015-RIA - - - 686764 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 246 668,40 - - - Coupling ATomistics and mesoscAle Plasticity for toUghness of noveL hybrid maTerial - - - EUR 246 668,40 - - - France - - - Research Organisations - - The project is one of an interactive synergism between theoretical modelling at UC Berkeley's MSE department and the CNRS-LEM and multiple length-scale structural/mechanical characterization and innovative processing at UCB. - The researcher will lead the project under the supervision of Pr. Asta (UCB) and Dr. Finel (LEM). The work will be done in strong collaboration with Dr. Devincre (LEM) and experimentalist Pr. Ritchie (UCB). As structural materials reach their - performance limits, one of the major scientific challenges for the 21st century is the development of new lightweight, high-performance structural materials to support advances in diverse strategic fields from building to transportation or energy. - Tomsia and Ritchie have designed a freeze-casting technique to synthesize materials that closely mirror the hierarchical microstructure of nacre, producing the highest toughness ceramics on record. Now, our goal is to improve the material strength as - well as toughness. Preliminary results have been recently obtained in the form of Al2O3/Al-Si composites exhibiting high toughness but a strength still 30% lower than pure metal. Our project aims to identify, characterize and model the material - fracture, involving physical processes at many length scales and, finally, to design hybrid material with optimized mechanical properties. Our efforts to define the scientific mechanisms needed to develop such new damage-tolerant materials will - follow an innovative multi-scale approach: combination of first-principles modelling of the interfaces and micro-mechanics models of bulk elastic and plastic relaxation, together with experimental data. - - 2020-01-31, ongoing project - - - 2017-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - France - - - CATAPULT - - - H2020-MSCA-IF-2015 - - - 702731 - - - - - EBERHARD KARLS UNIVERSITAET TUEBINGEN - EBERHARD KARLS UNIVERSITAET TUEBINGEN - - - EUR 1 998 898 - - - Functional in vivo analysis of cholangiocarcinoma development, progression and metastasis. - - - EUR 1 998 898 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Genetic heterogeneity and complexity are hallmarks of metastatic solid tumors and therapy resistance inevitably develops upon treatment with cytotoxic drugs or molecular targeted therapies. Cholangiocarcinoma (CCC, or bile - duct cancer) represents the second most frequent primary liver tumor and has emerged as a health problem with sharply increasing incidence rates, in particular of intrahepatic CCC (ICC). The reason for increased CCC incidence remains unclear, but - influences of western lifestyle and a resulting altered hepatic metabolism have been discussed. Surgical resection represents the only curative option for the treatment of CCC, however, many tumors are irresectable at the time of diagnosis. CCC - represents a highly aggressive and metastatic tumor type and currently no effective systemic therapy regimen exists. The overall molecular mechanisms driving CCC formation and progression remain poorly characterized and it thus becomes clear that a - detailed molecular characterization of cholangiocarcinogenesis and the identification of robust therapeutic targets for CCC treatment are urgently needed. Taking advantage of our strong expertises in chimaeric (mosaic) liver cancer mouse models and - stable in vivo shRNA technology, we here propose a comprehensive and innovative approach to i) dissect molecular mechanisms of cholangiocarcinogenesis, with a particular emphasis on Kras driven ICC development from adult hepatocytes and oncogenomic - profiling of ICC metastasis, ii) to employ direct in vivo shRNA screening to functionally identify new therapeutic targets for CCC treatment and iii) to characterize the role of the gut microbiome for CCC progression and metastasis. We envision this - ERC-funded project will yield important new insights into the molecular mechanisms of CCC development, progression and metastasis. As our work comprises direct and functional strategies to identify new vulnerabilities in CCC, the obtained data harbor - a very high translational potential. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - CholangioConcept - - - ERC-2014-CoG - - - 648084 - - - - - EBERHARD KARLS UNIVERSITAET TUEBINGEN - - - EUR 159 460,80 - - - Morphogen-like properties of small RNA gradients: A new paradigm for the role of small RNAs in developmental biology - - - EUR 159 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - This fellowship will investigate the mechanisms by which small RNAs function as novel intercellular messengers that provide important developmental signals. By manipulating various small RNA gradient and target parameters, the - proposed research seeks to understand how small RNA gradients are interpreted into sharp gene expression domains. The findings from the proposed experiments will provide important insight into the patterning properties of small RNA gradients, and - their role in conferring robustness to developmental programs in both plants and animals. The approach taken is a multidisciplinary one that integrates mathematical modelling with qualitative experimental data, generated from a novel reporter system - and state-of-the-art confocal imaging and image analysis. The outcome will be a new paradigm for how miRNAs function in development, which will provide important insight into the patterning properties of small RNA gradients. - - 2019-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - MorphGrad - - - H2020-MSCA-IF-2015 - - - 709293 - - - - - MALMO HOGSKOLA - - - EUR 185 857,20 - - - Molecular Imprinting mediated regulation of cell behavior and related biomedical applications - - - EUR 185 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - Tissue engineering or regenerative medicine, with its ultimate aim of developing true human replacement parts, has recently made enormous progress. The field refers to the use of human cells to replace or regenerate tissues or - organs. Ideally, biomaterials for tissue engineering should efficiently mimic functionalities of the natural extracellular matrix (ECM). Hence surfaces of biomaterials should be engineered for dynamic control of cell behaviour. The objective of this - proposal is to exploit molecular imprinting as a dynamic methodology for biofunctionalization and tissue engineering. Building on our previous proof of concept demonstration of systems for cell sheet harvesting, we expect to hereby obtain dynamic - biofunctionalization of surfaces and overcome limitations of currently used methodologies (e.g. ligand leaching in non-covalent approach, loss of bioactivity in covalent approach, and lack of means for dynamic control of cells adhesion in both). The - specific objectives of the proposal are as follows: - - 2018-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - MIP4CELL - - - H2020-MSCA-IF-2014 - - - 658953 - - - - - EBERHARD KARLS UNIVERSITAET TUEBINGEN - EBERHARD KARLS UNIVERSITAET TUEBINGEN - - - EUR 1 497 125 - - - Biochemically modified messenger RNA encoding nucleases for in vivo gene correction of severe inherited lung diseases - - - EUR 1 497 125 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Surfactant Protein B (SP-B) deficiency and Cystic Fibrosis (CF) are severe, fatal inherited diseases affecting the lungs of ten thousands of people, for which there is currently no available cure. Although gene therapy is a - promising therapeutic approach, various technical problems, including numerous physical and immune-mediated barriers, have prevented successful application to date. My recent studies were the first to demonstrate the life-saving efficacy of repeated - pulmonary delivery of chemically modified messenger RNA (mRNA) in a mouse model of congenital SP-B deficiency. By incorporating balanced amounts of modified nucleotides to mimic endogenous transcripts, I developed a safe and therapeutically efficient - vehicle for lung transfection that eliminates the risk of genomic integration commonly associated with DNA-based vectors. I also assessed the delivery of mRNA-encoded site-specific nucleases to the lung to facilitate targeted gene correction of the - underlying disease-causing mutations. In comprehensive studies, we show that a single application of nucleases encoded by nucleotide-modified RNA (nec-mRNA) can generate in vivo correction of terminally differentiated alveolar type II cells, which - more than quadrupled the life span of SP-B deficient mice. Together with my working group, I aim to further develop this technology to enhance the efficiency and safety of nec-mRNA-mediated in vivo lung stem cell targeting, providing an ultimate cure - by permanent correction. Specifically, we will test this approach in humanized mouse models of SP-B deficiency and CF. Developing and genetically engineering humanized models in vivo will be a critical step towards the safe translation of mRNA based - nuclease technology to the clinic. With my competitive edge in lung-transfection technology and strong data, I feel that my group is uniquely suited to achieve these goals and to make a highly valuable contribution to the development of an efficient - treatment. - - 2020-03-31, ongoing project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - BREATHE - - - ERC-2014-STG - - - 637752 - - - - - REGION HOVEDSTADEN - - - EUR 200 194,80 - - - Omics Phenotyping of Endocrine Disease in the General Population - - - EUR 200 194,80 - - - Denmark - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Metabolomics is a relatively new technology that provides information about levels of human metabolites, the low molecule products at the end (downstream) of the metabolic pathways of human physiology. In theory, metabolite - profiles may more closely reflect the clinical phenotype and thus potentially improve risk prediction. Another advantage is that that they can be performed on non-invasive biofluids like urine. Several metabolomics studies have suggested that the - metabolite profile of an individual can be used as a predictor of type 2 diabetes. However, evidence from large-scale population-based studies with comprehensive phenotypes of diabetes and thyroid disease is limited. The aim of the project is to - identify urine metabolite profiles associated with risk of diabetes and thyroid disease and to investigate pathogenetic pathways by identifying genetic determinants of these metabolites. The project takes advantage of the long tradition of - population-based and registry-based epidemiological research in Denmark. The experienced researcher will complete a training program supervised by two recognised Danish research institutions with complementary expertise in the fields of epidemiology - and genetics, respectively. Hereby the experienced researcher will achieve competences in the field of statistical modelling of epidemiological data with repeated measures and use of the unique Danish registries for research. Furthermore, during the - secondment at the partner institution the experienced researcher will receive training in genetic epidemiology. In return, knowledge of metabolomics will be translated to the beneficiary and partner organizations. It is expected that the results will - provide novel insights into the pathophysiology of diabetes and thyroid disease and identify novel biomarkers to improve risk prediction in individuals. - - 2017-07-31, closed project - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - OPEDGP - - - H2020-MSCA-IF-2014 - - - 657595 - - - - - EBERHARD KARLS UNIVERSITAET TUEBINGEN - - - EUR 239 860,80 - - - The impact of climate change on the uptake of arsenic into rice - - - EUR 239 860,80 - - - Germany - - - Higher or Secondary Education Establishments - - Rice is the staple food worldwide. Unfortunately, global rice yield is already falling behind population growth. One of the reasons for this is the presence of toxic arsenic (As) in many South(-East) Asian paddy soils, which - is known to decrease rice growth and productivity. The current change in Earth’s climate is known to cause land loss due to desertification and inundation and lower (rice) crop yields, thus, threatening the global food security. According to the - highest emission scenario for greenhouse gases presented in the 5th assessment report of the IPCC, global annual temperatures could rise by more than 5°C by the year 2100. How increased temperatures and CO2 concentrations affect As uptake into rice - and ultimately the quality and production of rice is unknown and the main research question of this proposal. Rice will be grown in fully controlled growth chambers with elevated temperature and partial pressure of CO2, simulating the cli-mate of the - year 2100. Besides determining changes in rice growth and grain yield, the amount of organic and inorganic As in the grain will be determined to assess rice quality. Furthermore, the biogeochemical pro-cesses occurring in the soil and atmosphere - during climate change will be investigated and thus, will allow to understand the observed changes in rice yield and quality due to climate change. The amount and speciation of As will be quantified in the soil, plant, and atmosphere. Changes in - microbial community abundance and richness will be assessed with modern pyrosequencing techniques. Functional microbial guilds of interest (iron and arsenic metabolizing bacteria) will be assessed by qPCR, pyrosequencing, and clone libraries. - Overall, the knowledge obtained within the MSC-GF action on the impact of climate change on As uptake by rice will allow a better risk assessment for productivity of rice in the future and may give ideas for how to prevent a loss in rice yield and - quality in a strongly climate impacted future. - - 2019-03-29, ongoing project - - - 2016-03-30 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Germany - - - RACe - - - H2020-MSCA-IF-2014 - - - 661674 - - - - - PANEPISTIMIO THESSALIAS - - - EUR 164 653,20 - - - Music in Detention during the (Post) Civil-War Era in Greece (1947-1957) - - - EUR 164 653,20 - - - Greece - - - Higher or Secondary Education Establishments - - MUSDEWAR will investigate the use of music in Greek prison camps in the (post) civil-war era (1947-1957). Despite a recent shift in musicology, which has begun to address music’s potential to damage subjectivity, there are - still major gaps in the history of music’s use in mass detention camps. Contributing to the wider history of detention camps in the twentieth century, MUSDEWAR will fill this gap by critically examining: (1) the use of music as a means to - ‘re-educate’, punish, humiliate and ‘break’ prisoners; (2) ‘performance under orders’: official camp orchestras and choirs; (3) music compositions, performances, and debates on Greek music by intellectuals-detainees. Analysing these aspects will - combine historical and empirical research with a critical and theoretical framework. The project will document and reconstruct the use of music and musical life in the camps through archival and textual research, and interviews with former detainees, - composers and intellectuals of the time. An interdisciplinary framework will be developed to analyse and interpret research findings, using tools from musicology, history, philosophy, trauma studies and critical theory. MUSDEWAR will deliver a - monograph to a major international academic publisher. Moving beyond the humanistic notion of music as an inherently enlightening art, the monograph will synthesize research into an empirically rich and theoretically grounded account of the - multifaceted use of music in the Greek camps. Intermediate aims include a project website and two articles to peer-reviewed journals. Actions for networking and knowledge transfer include research presentations, a workshop, a public outreach event - (symposium, exhibition), projects in secondary schools, and a proposal for a European Research Council Starting Grant. Results will contribute directly to trans-national public debates about human rights and current forms of detention, particularly - with regard to mass asylum seeking in the European Union. - - 2019-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - Greece - - - MUSDEWAR - - - H2020-MSCA-IF-2015 - - - 706016 - - - - - SCIENCE AND TECHNOLOGY FACILITIES COUNCIL - UNIVERSITA DEGLI STUDI DI MILANO - ATHINA-EREVNITIKO KENTRO KAINOTOMIAS STIS TECHNOLOGIES TIS PLIROFOFORIAS, TON EPIKOLNONION KAI TIS GNOSIS - DEUTSCHES ZENTRUM FUER LUFT - UND RAUMFAHRT EV - - - EUR 1 999 983,75 - - - Support to Reinforce the European Strategy Forum for Research Infrastructures - - - EUR 1 999 983,75 - - - United Kingdom - Italy - Greece - Germany - - - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - - A 4 year "Coordination and Support Action" project led by the Science Technology Facilities Council (UK) in partnership with Universita degli Studi di Milano, (Italy), ATHENA Research and Innovation Centre, (Greece) and German - Aerospace Center, DLR (Germany). - - - 2019-02-28, ongoing project - - - 2015-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.3.1."> - - - INFRASUPP-5-2014 - Policy measures for research infrastructures - - - CSA - Coordination and support action - - - United Kingdom - - - STR- ESFRI - - - H2020-INFRASUPP-2014-2 - - - 654213 - - - - - MUSEO STORICO DELLA FISICA E CENTRO STUDI E RICERCHE ENRICO FERMI - ITA-SUOMEN YLIOPISTO - Masarykova univerzita - CHARLES RIVER DISCOVERY RESEARCH SERVICES FINLAND OY - - - EUR 540 000 - - - Advanced MR methods for characterization of microstructural brain damage - - - EUR 540 000 - - - Italy - Finland - Czech Republic - Finland - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - NMR (Nuclear Magnetic Resonance)-based approaches have affirmed as extremely valuable for applications in neurosciences. Nonetheless, the exquisite flexibility of tissue contrast in magnetic resonance imaging (MRI) that can be - obtained by proper manipulation of nuclear spins still offers room for technological improvements which can be quickly expanded to clinical routine. In particular, there is extreme need of imaging methods that allow a correct assessment of - microstructural damage in many brain diseases, including – but not limited to – neurodegenerative diseases. Indeed, current MRI techniques suffer from poor specificity and ultimately lack the ability to identify the microscopic biophysical and - biological mechanisms related to the specific features of the pathology. - - 2019-10-31, ongoing project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Italy - - - MICROBRADAM - - - H2020-MSCA-RISE-2015 - - - 691110 - - - - - ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS - NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - PANEPISTIMIO PATRON - PANEPISTIMIO THESSALIAS - - - EUR 205 413 - - - 2014-2015 Researchers' Night: The Greek events - - - EUR 219 812,50 - - - Greece - Greece - Greece - Greece - Greece - - - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - ReN2014-5 events will be organized during 2014 and 2015 and will take place in six major cities: i) Athens, Greece’s capital, ii) Thessaloniki, iii) Patras, iv) Heraklion, v) Volos and for the first time in vi) Corfu, the - capital of the Ionian Islands. These cities are spread almost nation-wide and cover more than two-thirds of Greece’s total population ensuring a first-hand experience of ReN2014-5 activities from a large audience. - - 2015-11-30, closed project - - - 2014-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.5."> - - - MSCA-NIGHT-2014 - European Researchers' Night (NIGHT) - - - CSA - Coordination and support action - - - Greece - - - ReN2014-15 - - - H2020-MSCA-NIGHT-2014 - - - 633303 - - - - - ETHNIKO DIKTYO EREVNAS TECHNOLOGIAS AE - THE CYPRUS INSTITUTE - INSTITUTE OF INFORMATION AND COMMUNICATION TECHNOLOGIES - INSTITUT ZA FIZIKU - KORMANYZATI INFORMATIKAI FEJLESZTESI UGYNOKSEG - NEMZETI INFORMACIOS INFRASTRUKTURA FEJLESZTESI IRODA - UNIVERSITATEA DE VEST DIN TIMISOARA - UNIVERSITETI POLITEKNIK I TIRANES - UNIVERZITET U BANJOJ LUCI - Ss. CYRIL AND METHODIUS UNIVERSITY IN SKOPJE - JAVNA USTANOVA UNIVERZITET CRNE GORE PODGORICA - RESEARCH AND EDUCATIONAL NETWORKING ASSOCIATION OF MOLDOVA - INSTITUTE FOR INFORMATICS AND AUTOMATION PROBLEMS OF THE NATIONAL ACADEMY OF SCIENCES OF THE REPUBLIC OF ARMENIA - GEORGIAN RESEARCH AND EDUCATIONAL NETWORKING ASSOCIATION - BIBLIOTHECA ALEXANDRINA*LIBRARY OFALEXANDRIA BIBALEX - MACHBA - INTERUNIVERSITY COMPUTATION CENTER - SYNCHROTRON-LIGHT FOR EXPERIMENTAL SCIENCE AND APPLICATIONS IN THE MIDDLE EAST - - - EUR 3 300 000 - - - VRE for regional Interdisciplinary communities in Southeast Europe and the Eastern Mediterranean - - - EUR 3 300 000 - - - Greece - Cyprus - Bulgaria - Serbia - Hungary - Hungary - Romania - Albania - Bosnia and Herzegovina - Former Yugoslav Republic of Macedonia - Montenegro - Moldova - Armenia - Georgia - Egypt - Israel - Jordan - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - Research Organisations - Other - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - In the last decade, a number of initiatives were crucial for enabling high-quality research - by providing e-Infrastructure resources, application support and training - in both South East Europe (SEE) and Eastern - Mediterranean (EM). They helped reduce the digital divide and brain drain in Europe, by ensuring access to regional e-Infrastructures to new member states, states on path to ascension, and states in European Neighborhood Policy area – in total 14 - countries in SEE and 6 in EM. This VI-SEEM proposal brings together these e-Infrastructures to build capacity and better utilize synergies, for an improved service provision within a unified Virtual Research Environment (VRE) for the - inter-disciplinary scientific user communities in the combined SEE and EM regions (SEEM). - - 2018-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.3."> - - - EINFRA-9-2015 - e-Infrastructures for virtual research environments (VRE) - - - RIA - Research and Innovation action - - - Greece - - - VI-SEEM - - - H2020-EINFRA-2015-1 - - - 675121 - - - - - LAPIN YLIOPISTO - UNIVERSITY OF LEEDS - PACO DESIGN COLLABORATIVE - POLYTECHNIC OF NAMIBIA PON - - - EUR 945 000 - - - Participatory Tools for Human Development with the Youth - - - EUR 945 000 - - - Finland - United Kingdom - Italy - Namibia - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Challenges faced by the marginalized youth in developing countries, such as unemployment, are not simple or easily solved. This is influenced by a number of factors including levels of education, gender, self-esteem, - geographic location, physical ability and transport. The objective of the project is to contribute to solving the issues related to the youth unemployment in developing countries by creating participatory tools for human development that enable - transformational change for the youth. Based on a service design approach, the project will provide tools for the marginalized youth suitable for daily use, enhancing regional democracy, increasing equal opportunities and contributing to human and - service development with a particular target group: the San people in South Africa and Namibia. The San are faced with various social, cultural and political difficulties, and their communities are among the poorest in their countries, which are - among the most unequal societies in the world. The tools aim to support the youth’s motivation and abilities to participate in the development of their own community towards a wider integration into their national socio-economic systems. - - - 2019-01-31, ongoing project - - - 2015-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Finland - - - PARTY - - - H2020-MSCA-RISE-2014 - - - 645743 - - - - - FONDAZIONE BRUNO KESSLER - GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER - TECHNISCHE UNIVERSITAET WIEN - UNIWERSYTET WARSZAWSKI - TECHNISCHE UNIVERSITEIT DELFT - INSTITUT NATIONAL DE L'INFORMATION GEOGRAPHIQUE ET FORESTIERE - ORDNANCE SURVEY LTD - INSTITUT CARTOGRAFIC I GEOLOGIC DE CATALUNYA - CENTRUL NATIONAL DE CARTOGRAFIE - GEODETSKI ZAVOD CELJE IZVAJANJE STROKOVNO-OPERATIVNIH DEL STORITEV V ZADEVAH GEODETSKE SLUZBE TER DRUGIHSTROKOVNO TEHNICNIH DEL DOO - VERMESSUNG AVT-ZT-GMBH - VEXCEL IMAGING GMBH - GEOIMAGING LIMITED - - - EUR 1 021 500 - - - innoVation in geOspatiaL and 3D daTA - - - EUR 1 021 500 - - - Italy - Germany - Austria - Poland - Netherlands - France - United Kingdom - Spain - Romania - Slovenia - Austria - Austria - Cyprus - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Geodata are datasets that have a spatial, temporal and thematic aspect to describe phenomena and processes in time, space and topic. Geodata, or geospatial data, are nowadays collected and produced with various sensors and - techniques which provide for images, 3D point clouds, thematic maps, etc. Geodata are used in many Geosciences and for various applications such as urban planning, territorial management, damage assessment, environmental monitoring, 3D city - modelling, renewable energy assessment, land registry, heritage documentation, etc. Despite a growing market, a large number of applications, a vast series of publications and various acquisition and processing techniques, there are still many - unresolved research questions on the automation of processing procedures, and on how to make them more reliable, powerful and scale-invariant. Moreover, an efficient availability, access and use of geospatial data are often missing. This hinders the - growth of new applications and societal welfares. Progress in provision of efficiently and effectively derived 3D geospatial information is thus the key to more comprehensive, faster and better exploitation of geodata, for the benefit of individuals - and societies. Last but not least, new occupations are emerging in the geospatial industry which requires capacity building for developing new applications of geospatial technologies. The VOLTA project, through secondments, training activities and - networking, will facilitate knowledge exchange and career progresses in the geospatial field. The project will develop innovative solutions to (i) automatically provide metric information from images, (ii) fuse heterogeneous data coming from various - sensors, (iii) segment 2D and 3D geospatial data and (iv) process large geospatial datasets in the Cloud. The project will share and exploit the complementary expertise of the partners to produce and transfer new skills and innovative solutions for - mapping agencies and geospatial companies. - - 2021-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Italy - - - VOLTA - - - H2020-MSCA-RISE-2016 - - - 734687 - - - - - ACADEMISCH ZIEKENHUIS GRONINGEN - - - EUR 1 674 240 - - - Personalised Medicine in Diabetic Chronic Disease Management - - - EUR 3 348 480 - - - Netherlands - - - Higher or Secondary Education Establishments - - Diabetes is increasing rapidly from 415 million patients in 2015 to 642 million patients by 2040. As a result, it will become the leading disease worldwide, affecting 1 out of 10 persons globally and 3 out of 4 in low and - middle income countries. The World Health Organisation marked World Health Day 2016 as calling for action on diabetes. Despite successful treatment of the inadequate glucose handling, diabetic patients show long-term effects of the disease such as a - progressive loss of multiple organ function, in particular in the cardiovascular and renal systems. About half of the diabetic patients are at risk for renal complications associated with a markedly increased disease burden and death rate, the latter - even surpassing the death rate in all treated cancer patients. The major reason for the lack of treatment efficacy is the large variation in individual response to the treatment. Consequently, we are left with a huge unmet need in the treatment of - this chronic disease. - - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2016 - Co-funding of regional, national and international programmes - - - MSCA-COFUND-DP - Doctoral programmes - - - Netherlands - - - PROMINENT - - - H2020-MSCA-COFUND-2016 - - - 754425 - - - - - KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW - - - EUR 165 598,80 - - - Social Distress Response in the Context of Empathy in Rats - - - EUR 165 598,80 - - - Netherlands - - - Research Organisations - - "Why do humans behave pro-socially to such an extent that it supports the life of other individuals? Similarly, why do certain people harm others by hurting and sometimes killing? Finally, how can we promote pro-sociality and - limit harmful actions? The philosopher and economist Adam Smith considered that what motivates us to help a person is that we can "place ourselves in his situation, we conceive ourselves enduring all the same torments", thus, holding empathy as the - driving force of prosociality. - - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - SOCIORATS - - - H2020-MSCA-IF-2016 - - - 745885 - - - - - Eidgenössische Technische Hochschule Zürich - Eidgenössische Technische Hochschule Zürich - - - EUR 2 495 755 - - - Tailored chemical complexity through evolution-inspired synthetic biology - - - EUR 2 495 755 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Creating true molecular complexity in a modular, combinatorial fashion is one of the great visions in applied enzymology and chemistry. Nature achieves this feat by using modular biosynthetic enzymes. These microbial proteins - generate many of the most important natural products of therapeutic value, including antiinfective, anticancer, and immunosuppressive agents. To construct such compounds, each enzyme module incorporates and often modifies one building block in an - assembly line-like process. Among the known modular enzymes, the recently discovered trans-acyltransferase polyketide synthases (trans-AT PKSs) exhibit an unparalleled biosynthetic diversity and tendency to form extensively mosaic-like hybrid enzymes - during evolution. As a consequence, many bioactive polyketides generated by these enzymes exhibit combinatorial-like hybrid structures. This phenomenon provides unprecedented opportunities to understand the evolution of metabolic complexity and to - apply these principles to metabolic engineering through parts-based synthetic biology. SynPlex will use a novel hypothesis-driven, multi-faceted strategy to interrogate and utilize the distinct combinatorial properties and metabolic richness of - trans-AT PKSs. This multidisciplinary project aims to (i) unravel principles of how mosaic PKSs and their metabolites are formed in Nature, (ii) characterize non-canonical PKS components, (iii) create a toolbox of PKS parts for synthetic biology - based on these evolutionary and biochemical principles, and (iv) harness the combinatorial potential of trans-AT systems to access complex natural as well as non-natural products. This innovative concept that merges evolutionary biology, enzymology, - synthetic biology, and chemistry will result in a broad understanding of these most complex of all known proteins. It has the potential to provide generic, robust synthetic biology platforms to engineer complex polyketides with a wide range of - features in a predictable way. - - 2022-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Switzerland - - - SynPlex - - - ERC-2016-ADG - - - 742739 - - - - - THE HEBREW UNIVERSITY OF JERUSALEM - THE HEBREW UNIVERSITY OF JERUSALEM - - - EUR 2 498 750 - - - The emergence of Modern Hebrew as a case-study of linguistic discontinuity - - - EUR 2 498 750 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The pioneering enterprise I propose is the study of a particular type of linguistic discontinuity – language revival – inspired by the revival of Hebrew at the end of the 19th century. The historical and sociocultural - dimensions the revival have been studied before, but not its linguistic dimensions. My main aim is to construct a model of the linguistic factors which have shaped the revival of Hebrew. I expect this model to provide clues for the understanding of - the process of language revival in general. For a language to be revived, a new grammar must be created by its native speakers. I hypothesize that the new grammar is formed by some of the general principles which also govern other better known cases - of linguistic discontinuity (creoles, mixed languages, emergent sign languages etc.). The model I will develop will lay the foundation for a new subfield within the study of discontinuity – the study of language revival. I will start with careful - work of documenting the development of the grammar of Modern Hebrew, in particular its syntax, something which has not been done systematically before. One product of the project will be a linguistic application for the documentation and annotation - of the novel syntactic constructions of Modern Hebrew, their sources in previous stages of Hebrew and in the languages with which Modern Hebrew was in contact at the time of the revival, and the development of these constructions since the beginning - of the revival until the present time. The linguistic application will be made available on the web for other linguists to use and to contribute to. The institution of an expanding data-base of the syntactic innovations of Modern Hebrew which - comprises both documentation/ annotation and theoretical modeling which could be applied to other languages makes this an extremely ambitious proposal with potentially wide-reaching ramifications for the revival and revitalization of the languages of - ethno-linguistic minorities world wide. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Israel - - - EMODHEBREW - - - ERC-2016-ADG - - - 741360 - - - - - THE HEBREW UNIVERSITY OF JERUSALEM - THE HEBREW UNIVERSITY OF JERUSALEM - - - EUR 2 499 750 - - - Coupled Nanocrystal Molecules: Quantum coupling effects via chemical coupling of colloidal nanocrystals - - - EUR 2 499 750 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Coupling of atoms is the basis of chemistry, yielding the beauty and richness of molecules and materials. Herein I introduce nanocrystal chemistry: the use of semiconductor nanocrystals (NCs) as artificial atoms to form NC - molecules that are chemically, structurally and physically coupled. The unique emergent quantum mechanical consequences of the NCs coupling will be studied and tailored to yield a chemical-quantum palette: coherent coupling of NC exciton states; dual - color single photon emitters functional also as photo-switchable chromophores in super-resolution fluorescence microscopy; electrically switchable single NC photon emitters for utilization as taggants for neuronal activity and as chromophores in - displays; new NC structures for lasing; and coupled quasi-1D NC chains manifesting mini-band formation, and tailored for a quantum-cascade effect for IR photon emission. A novel methodology of controlled oriented attachment of NC building blocks (in - particular of core/shell NCs) will be presented to realize the coupled NCs molecules. For this a new type of Janus NC building block will be developed, and used as an element in a Lego-type construction of double quantum dots (dimers), heterodimers - coupling two different types of NCs, and more complex NC coupled quantum structures. To realize this NC chemistry approach, surface control is essential, which will be achieved via investigation of the chemical and dynamical properties of the NCs - surface ligands layer. As outcome I can expect to decipher NCs surface chemistry and dynamics, including its size dependence, and to introduce Janus NCs with chemically distinct and selectively modified surface faces. From this I will develop a new - step-wise approach for synthesis of coupled NCs molecules and reveal the consequences of quantum coupling in them. This will inspire theoretical and further experimental work and will set the stage for the development of the diverse potential - applications of coupled NC molecules. - - 2022-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Israel - - - CoupledNC - - - ERC-2016-ADG - - - 741767 - - - - - DANMARKS TEKNISKE UNIVERSITET - DANMARKS TEKNISKE UNIVERSITET - - - EUR 2 500 000 - - - Discovering new Catalysts in the Cluster-Nanoparticle Transition Regime - - - EUR 2 500 000 - - - Denmark - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The purpose of this proposal is to establish new fundamental insight of the reactivity and thereby the catalytic activity of oxides, nitrides, phosphides and sulfides (O-, N-, P-, S- ides) in the Cluster-Nanoparticle - transition regime. We will use this insight to develop new catalysts through an interactive loop involving DFT simulations, synthesis, characterization and activity testing. The overarching objective is to make new catalysts that are efficient for - production of solar fuels and chemicals to facilitate the implementation of sustainable energy, e.g. electrochemical hydrogen production and reduction of CO2 and N2 through both electrochemical and thermally activated processes. - - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Denmark - - - CLUNATRA - - - ERC-2016-ADG - - - 741860 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 2 499 500 - - - Dynamic Interplay between Energy and Memory - - - EUR 2 499 500 - - - France - France - - - Research Organisations - Research Organisations - - Understanding the links between neuronal plasticity which underlies memory and energy metabolism is a major goal of brain studies. The brain is a main energy consumer and the central regulator of energy homeostasis, and it - prioritizes its own supply over peripheral organs. Interestingly, our work demonstrates that the brain is also able to regulate its own activity under energy shortage to favor survival. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - France - - - EnergyMemo - - - ERC-2016-ADG - - - 741550 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 657 055,52 - - - Corrosion Initiation Mechanisms at the Nanometric/Atomic Scale - - - EUR 1 657 055,52 - - - France - France - - - Research Organisations - Research Organisations - - The failure of metallic materials caused by corrosion strongly impacts our society with cost, safety, health and performance issues. The mechanisms of corrosion propagation are fairly well understood, and various means of - mitigation are known even if research is still necessary to improve this knowledge or to develop corrosion protection for the application of new materials. The vision of CIMNAS is that a major breakthrough for corrosion protection lies in a deep - understanding and control of the initiation stage triggering corrosion. Corrosion initiation takes place at the atomic/molecular scale or at a scale of a few nanometres (the nanoscale) on metal and alloy surfaces, metallic, oxidised or coated, and - interacting with the corroding environment. The mission of CIMNAS is to challenge the difficulty of understanding corrosion initiation at the nanometric/atomic scale on such complex interfaces, ultimately aiming at designing more robust metallic - surfaces via the understanding of corrosion mechanisms. The project is constructed on new ideas to achieve three knowledge breakthroughs, each answering a key question for the understanding of corrosion initiation on metal and alloy surfaces. It is - envisioned that the model approach used and the achieved breakthroughs will open up a new horizon for research on corrosion initiation mechanisms at the nanoscale, and new opportunities for a knowledge-based design of novel corrosion protection - technologies. Technologies presently at low TRL (Technology Readiness Level) will benefit from these breakthroughs. Resources will include a team of highly experienced and recognised researchers headed by the PI, a unique apparatus recently installed - at the PI’s lab, integrating surface spectroscopy, microscopy, and electrochemistry for in situ measurements in a closed system, novel experimental approaches, and a strong complementarity of experiments and modelling. - - 2021-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - France - - - CIMNAS - - - ERC-2016-ADG - - - 741123 - - - - - ISTITUTO NAZIONALE DI FISICA NUCLEARE - ISTITUTO NAZIONALE DI FISICA NUCLEARE - - - EUR 1 432 301 - - - Modeling the Gravitational Spectrum of Neutron Star Binaries - - - EUR 1 432 301 - - - Italy - Italy - - - Research Organisations - Research Organisations - - The most energetic electromagnetic phenomena in the Universe are believed to be powered by the collision of two neutron stars, the smallest and densest stars on which surface gravity is about 2 billion times stronger than - gravity on Earth. However, a definitive identification of neutron star mergers as central engines for short-gamma-ray bursts and kilonovae transients is possible only by direct gravitational-wave observations. The latter provide us with unique - information on neutron stars' masses, radii, and spins, including the possibility to set the strongest observational constraints on the unknown equation-of-state of matter at supranuclear densities. - - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Italy - - - BinGraSp - - - ERC-2016-STG - - - 714626 - - - - - VIB - VIB - - - EUR 1 996 705 - - - Determining the instructive tissue signals and the master transcription factors driving Kupffer cell differentiation - - - EUR 1 996 705 - - - Belgium - Belgium - - - Research Organisations - Research Organisations - - We have recently shown that contrary to common hypotheses, circulating monocytes can efficiently differentiate into Kupffer cells (KCs), the liver-resident macrophages. Using self-generated knock-in mice that allow specific KC - depletion, we found that monocytes colonize the KC niche in a single wave upon KC depletion and rapidly differentiate into self-maintaining KCs that are transcriptionally and functionally identical to their embryonic counterparts. This implies that: - (i) access to the KC niche is tightly regulated, ensuring that monocytes do not differentiate into KCs when the KC niche is full but differentiate very efficiently into KCs upon temporary niche availability, and (ii) imprinting by the KC niche is the - dominant factor conferring KC identity. Understanding which cells represent the macrophage niche, which signals produced by these cells imprint the tissue-specific macrophage gene expression profile and through which transcription factors (TxFs) this - is mediated is emerging as the next challenge in the field. We here propose an original strategy combining state-of-the-art in silico approaches and unique in vivo transgenic mouse models to tackle this challenge specifically for KCs, the most - abundant macrophage in the body. We hypothesize that the liver sinusoidal endothelial cell (LSEC) to which the KC is attached represents the most likely candidate to sense KC loss, recruit new monocytes and drive their differentiation into KCs. Thus, - this proposal aims to: (I) determine the TxFs through which the niche imprints KC identity, (II) map the LSEC-KC crosstalk during KC development, (III) generate LSEC-specific knock-in mice to study LSECs in vivo, (IV) demonstrate which LSEC factors - influence KC development and function. Importantly, understanding how the KC-TxFs and the LSEC-KC crosstalk control KC development and function will be essential for the development of novel therapeutic interventions for hepatic disorders in which - KCs play a central role. - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Belgium - - - KupfferCellNiche - - - ERC-2016-COG - - - 725924 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 173 076 - - - Polysaccharide-based membrane for sublingual vaccination - - - EUR 173 076 - - - France - - - Research Organisations - - Vaccination has been acknowledged as one of the most effective methods against life-threatening diseases. Vaccines administered by the mucosal route (oral, vaginal…) present the advantage to be needle-free and reduce the risk - of pathogen transmission. Among the existing mucosal vaccines, the sublingual ones are an interesting way of immunization since the sublingual mucosa is particularly thin and would allow easy penetration of antigens. Also, this administration allows - to bypass the gastrointestinal tract, has better safety record than intranasal vaccines and have better compliance for vaccinating infants and children. Additionally, they have a fast removal by body fluids and enzymes. PolyVac introduces a - pioneering system for controlled targeted delivery of bioactive molecules and, for the proof of concept envisages the development of a sublingual vaccine for HIV. This concept comprises the development of a free-standing (FS) multilayer membrane that - will present the double specificity to be immunoactive and specifically target the immune cells. To achieve this end, the FS will be loaded with a model antigen for immunotherapy and a chemotactic cytokine to specifically target the antigen - presenting cells. Once loaded with the proteins, the FS membrane will become a bioactive patch. This patch will permit to deliver subunit vaccine components both spatially and temporally as dendritic cells will be attracted at the sublingual - mucosa/patch interface ensuring efficient immune responses. Preclinical studies will follow in mice, by monitoring their immune response, for clinical translation and commercialisation of the proposed technology. It is expected to have, as final - product, an innovative sublingual patch for human immunotherapy that among the advantages presented above will also overcome one of the main drawbacks of injected vaccines that is the storage at around 4°C. Overcoming this issue they could be widely - used for immunotherapy in the developing countries. - - 2019-07-06, ongoing project - - - 2017-07-07 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - PolyVac - - - H2020-MSCA-IF-2016 - - - 751061 - - - - - EBERHARD KARLS UNIVERSITAET TUEBINGEN - - - EUR 159 460,80 - - - Understanding the impact of parental occupation on gender differences in field of study choice in Germany - - - EUR 159 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - While in many countries women have been increasing their participation in higher education, fields of study continue to be segregated by gender. Men dominate the technical fields which include mathematics, engineering and the - physical sciences, whereas women tend to engage in areas that have a social and caring dimension. Despite numerous policies to enhance gender equalities in society, gender segregation in higher education, ironically, appears to be more pronounced in - post-industrial countries, such as Germany, than in developing/transforming societies. - - 2019-10-01, ongoing project - - - 2017-10-02 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - GENSEG - - - H2020-MSCA-IF-2016 - - - 749068 - - - - - IQUADRAT INFORMATICA SL - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE TECNOLOGIC DE TELECOMUNICACIONS DE CATALUNYA - KUNGLIGA TEKNISKA HOEGSKOLAN - ARISTOTELIO PANEPISTIMIO THESSALONIKIS - TECHNISCHE UNIVERSITEIT EINDHOVEN - EDUCATIONAL OTE AE - III-V LAB - SIAE MICROELETTRONICA SPA - - - EUR 3 797 921,88 - - - 5G System Technological Enhancements Provided by Fiber Wireless Deployments - - - EUR 3 797 921,88 - - - Spain - France - Spain - Sweden - Greece - Netherlands - Greece - France - Italy - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - 5G cellular networks are coming and they need to cope with major challenges in meeting the demands of large populations. The rapid increase of mobile devices, wireless connections and the emerging internet services related to - applications with very diverse communication requirements (e.g., Smart grid, m-health, Smart cities), raised the need of higher capacity and more energy efficient networks with improved coverage capabilities. According to the 5G Public-Private - Partnership (5GPPP) recently formed by the European Commission (EC), 5G networks should be capable of providing 1000 times higher capacity with 0% downtime, enabling the roll-out of very dense wireless networks that are able to connect over 7 - trillion devices amongst 7 billion people. 5G STEP FWD aims at proposing, studying, optimizing, quantitatively assessing and comparing advantages and disadvantages of hybrid fiber – wireless architectures, topologies and technologies, which will - significantly shape 5G standards and will enable the requested 1000 times increase of spectral efficiency and 90% reduction of energy consumption. - - 2021-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Spain - - - 5G STEP FWD - - - H2020-MSCA-ITN-2016 - - - 722429 - - - - - VIB - VIB - - - EUR 1 999 660 - - - Decoding and controlling cell-state switching: A bottom-up approach based on enhancer logic - - - EUR 1 999 660 - - - Belgium - Belgium - - - Research Organisations - Research Organisations - - Cell-state switching in cancer allows cells to transition from a proliferative to an invasive and drug-resistant phenotype. This plasticity plays an important role in cancer progression and tumour heterogeneity. We have made a - striking observation that cancer cells of different origin can switch to a common survival state. During this epigenomic reprogramming, cancer cells re-activate genomic enhancers from specific regulatory programs, such as wound repair and - epithelial-to-mesenchymal transition. - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Belgium - - - cis-CONTROL - - - ERC-2016-COG - - - 724226 - - - - - TECHNISCHE UNIVERSITEIT DELFT - - - EUR 165 598,80 - - - Bichromatic Structures for Robust propagation of Light - - - EUR 165 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - The investigation of topological effects in photonic systems is a thriving field of research in the nanophotonics community. Suitably designed nanostructures allow the formation of novel states for light which are more robust - against disorder and less sensitive to back-scattering, spurring academic fascination and helping to improve photonic circuitry technology. Recent advances have greatly expanded the variety of systems displaying topological effects: for instance it - has recently been shown that the Aubry-André model, a one-dimensional tight-binding model of particles with a periodically-modulated on-site energy, inherits the nontrivial topological properties of a higher-dimensional topological insulator. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - BISTRO-LIGHT - - - H2020-MSCA-IF-2016 - - - 748950 - - - - - EBERHARD KARLS UNIVERSITAET TUEBINGEN - EBERHARD KARLS UNIVERSITAET TUEBINGEN - - - EUR 1 999 250 - - - Human Evolution at the Crossroads - - - EUR 1 999 250 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The most important open questions in European paleoanthropology concern the timing, number and origin of early human dispersals into the continent, the identity and number of taxa present, and their possible interactions. - These issues remain unresolved partly due to the lack of research in South-East Europe, a region at the crossroads between continents and a refugium for fauna, flora and possibly human populations during glacial times. The PI’s previous work there - (ERC StG PaGE) aimed to add new evidence to further our understanding of human evolution on the continent. PaGE led to the discovery of several new Paleolithic sites, including the oldest radiometrically dated archaeological site from South-East - Europe, placing the region squarely in the Paleolithic map of Europe. - - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - CROSSROADS - - - ERC-2016-COG - - - 724703 - - - - - POLITECNICO DI MILANO - POLITECNICO DI MILANO - - - EUR 149 375 - - - Innovative Neutron source for non destructive TEsting and tReatments - - - EUR 149 375 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The INTER project aims at the design and production of a proof of concept demonstrator component essential for the development of a novel, tunable and portable neutron source. - - - 2018-10-31, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Italy - - - INTER - - - ERC-2016-PoC - - - 754916 - - - - - MALMO HOGSKOLA - PHASE HOLOGRAPHIC IMAGING PHI AB - TURUN YLIOPISTO - BUNDESANSTALT FUER MATERIALFORSCHUNG UND -PRUEFUNG - KOBENHAVNS UNIVERSITET - UMEA UNIVERSITET - - - EUR 2 138 720,04 - - - Imaging and detection of tumor-associated glycan structures on tumor cells - - - EUR 2 138 720,04 - - - Sweden - Sweden - Finland - Germany - Denmark - Sweden - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The overall objective of Glyco Imaging is to develop novel assays for detection of glycans as biomarkers associated with aggressive and metastatic cancer forms. The assays will be developed for biomarker detection in blood, - urine, cells and tissue. Molecularly Imprinted Polymers (MIPs), or plastic antibodies, have been developed for targeting the human glycan sialic acid (SA), or Neu5Ac. The efficiency of the Neu5Ac specific SAMIPs targeted to the biomarker SA in - different solvents (methanol, water, phosphate buffer) will be exploited. The non-human Neu5Gc, which is incorporated into human glycoconjugates through dietary sources such as red meat, and shown to be involved in malignant cell transformation in - humans, will also be investigated by using highly specific Neu5Gc-SAMIPs. The imaging and detection techniques used will be based on fluorescence, 3D-viewing of cancer cells by digital holographic microscopy and magnetic separation columns. - - 2021-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Sweden - - - GlycoImaging - - - H2020-MSCA-ITN-2016 - - - 721297 - - - - - EBERHARD KARLS UNIVERSITAET TUEBINGEN - EBERHARD KARLS UNIVERSITAET TUEBINGEN - - - EUR 149 238 - - - PReparing Introduction to MArket of SKOTI (PRIMASKOTI) - a breakthrough solution for real-time studies of cytoskeletal motors at single-molecule resolution - - - EUR 149 238 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The PRIMASKOTI project will prepare the commercialization of SKOTI—the Swiss Knife for Optical Tweezers and Imaging. The scientific instrument SKOTI is designed to measure interactions between single biomolecules with a focus - on cytoskeletal molecular machines. SKOTI combines several state-of-the-art microscopy techniques with contact-less mechanical manipulation, so-called optical tweezers. Because of its ultra high stability, SKOTI has its particular strengths in - experiments requiring a solid support such as a glass surface. This requirement is often the case for cytoskeletal motor protein studies. Since these molecular machines are key to many essential cellular processes such as transport or cell division, - being able to study their interactions is an important step towards understanding diseases such as cancer or neurodegeneration. However, due to the highly specialized knowledge necessary to build and operate such instruments, hardly commercially - available, single-molecule experiments are difficult. By commercializing SKOTI, we aim to provide a simple-to-access tool which will broaden the scope of applications and users. SKOTI will provide a modular microscope and optical manipulation - platform with unprecedented force- and displacement-resolution, ease of operation through motorization and automatization, flexibility, and overall stability of the system. The key idea is to commercialize a complete solution, where the instrument is - supplemented with an isolation from the environment, operation and analysis software, specialized probes, service contracts, and kits for experiments that help to minimize preparation times. This approach will simplify single-molecule experiments, - increase throughput, and lower barriers to engage in such studies. In the long term, our novel, cutting-edge research tool for life sciences will provide insight to essential cellular processes and pave the way for new medical approaches. - - 2019-01-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Germany - - - PRIMASKOTI - - - ERC-2016-PoC - - - 755161 - - - - - NATIONAL OBSERVATORY OF ATHENS - - - EUR 164 653,20 - - - Improving global dust prediction and monitoring through data assimilation of satellite-based dust aerosol optical depth - - - EUR 164 653,20 - - - Greece - - - Research Organisations - - DUST-GLASS aims at improving global dust prediction and monitoring by optimizing an advanced data assimilation system (LETKF scheme) coupled with a sophisticated atmospheric-dust model (NMMB/BSC-Dust). For the accomplishment - of these core scientific goals, a fine resolution (0.1o x 0.1o) global dust optical depth (DOD) database, suitable for data assimilation, will be developed via a synergy of state-of-the-art Level 2 satellite retrievals acquired by MODIS, MISR and OMI - sensors (2007-2016). The impacts of assimilating this novel dataset (DOD) on model’s predictive skills, both at global and regional scale, will be assessed objectively. Global forecasts (5 days) will be carried out for different periods aiming at - studying dust aerosols’ mobilization and transport from the major dust sources of the planet, while a global reanalysis (0.5o x 0.7o) dataset will be generated for long-term dust monitoring. In addition, regional short-term (84 hours) forecasts will - be conducted for 20 Mediterranean dust outbreaks identified by a satellite algorithm in the framework of the MDRAF project (fellow’s previous MC-IEF). In the evaluation analysis, the model’s dust outputs will be compared versus measurements derived - by ground networks (AERONET, MAN, ACTRIS) as well as against columnar/vertical satellite retrievals (MODIS, MISR, CALIOP). Moreover, temperature and radiation will be also considered since “corrections” on dust fields, thanks to data assimilation, - are expected to be evident on both parameters due to dust-radiation interactions. The aforementioned variables will be compared against observations obtained by ground networks (ISB, RAOB, BSRN) and reanalysis/analysis products (ERA-Interim, FNL). - Considering the multifaceted role of dust, the scientific outcomes of DUST-GLASS are expected to contribute effectively to interdisciplinary studies regarding dust aerosols as well as their associated impacts on health, anthropogenic activities, - environment, weather and climate. - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Greece - - - DUST-GLASS - - - H2020-MSCA-IF-2016 - - - 749461 - - - - - THE UNIVERSITY OF EDINBURGH - THE UNIVERSITY OF EDINBURGH - - - EUR 1 499 520 - - - Establishing genetic code expansion as a tool to study neuronal circuit function in an animal - - - EUR 1 499 520 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - We pioneered technologies that allow the site-specific introduction of chemically synthesized unnatural amino acids (UAA) into a chosen protein within the context of a multicellular organism - the nematode worm C. elegans. The - foundational technology for this advance is genetic code expansion. - - 2021-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - UAAWORM - - - ERC-2015-STG - - - 679990 - - - - - WEIZMANN INSTITUTE OF SCIENCE - WEIZMANN INSTITUTE OF SCIENCE - - - EUR 2 287 500 - - - Immune checkpoint blockade for fighting Alzheimer’s disease - - - EUR 2 287 500 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Understanding, and ultimately treating Alzheimer’s disease (AD) is a major need in Western countries. Currently, there is no available treatment to modify the disease. Several pioneering discoveries made by my team, - attributing a key role to systemic immunity in brain maintenance and repair, and identifying unique interface between the brain’s borders through which the immune system assists the brain, led us to our recent discovery that transient reduction of - systemic immune suppression could modify disease pathology, and reverse cognitive loss in mouse models of AD (Nature Communications, 2015; Nature Medicine, 2016; Science, 2014). This discovery emphasizes that AD is not restricted to the brain, but is - associated with systemic immune dysfunction. Thus, the goal of addressing numerous risk factors that go awry in the AD brain, many of which are -as yet- unknown, could be accomplished by immunotherapy, using immune checkpoint blockade directed at the - Programmed-death (PD)-1 pathway, to empower the immune system. In this proposal, we will adopt our new experimental paradigm to discover mechanisms through which the immune system supports the brain, and to identify key/novel molecular and cellular - processes at various stages of the disease that are responsible for cognitive decline long before neurons are lost, and whose reversal or modification is needed to mitigate AD pathology, and prevent cognitive loss. Achieving our goals requires the - multidisciplinary approaches and expertise at our disposal, including state-of-the art immunological, cellular, molecular, and genomic tools. The results will pave the way for developing a novel next-generation immunotherapy, by targeting additional - selective immune checkpoint pathways, or identifying a specific immune-based therapeutic target, for prevention and treatment of AD. We expect that our results will help attain the ultimate goal of converting an escalating untreatable disease into a - chronic treatable one. - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Israel - - - ImmuneCheckpointsAD - - - ERC-2016-ADG - - - 741744 - - - - - WEIZMANN INSTITUTE OF SCIENCE - - - EUR 170 509,20 - - - Single cell analysis of the lung tumour-immune ecosystem: Developing new tools for effective immunotherapy - - - EUR 170 509,20 - - - Israel - - - Higher or Secondary Education Establishments - - Tumours evolve to evade immune surveillance through a series of immune suppression mechanisms. In line with this, cancer immunotherapies, in which the immune system is turned on against tumours, are currently revolutionizing - cancer treatment. Unfortunately, still many cancer patients do not respond to immunotherapies. Therefore, there is an urgent need to develop new tools for effective immunotherapy in order to increase treatment response rate. - - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Israel - - - SCALTIE - - - H2020-MSCA-IF-2016 - - - 746382 - - - - - UNIVERSITEIT ANTWERPEN - UNIVERSITEIT ANTWERPEN - - - EUR 1 966 530 - - - Seeing things you don't see: Unifying the philosophy, psychology and neuroscience of multimodal mental imagery - - - EUR 1 966 530 - - - Belgium - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - When I am looking at my coffee machine that makes funny noises, this is an instance of multisensory perception – I perceive this event by means of both vision and audition. But very often we only receive sensory stimulation - from a multisensory event by means of one sense modality. If I hear the noisy coffee machine in the next room (without seeing it), then how do I represent the visual aspects of this multisensory event? - - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Belgium - - - STYDS - - - ERC-2016-COG - - - 726251 - - - - - USTAV MOLEKULARNI GENETIKY AKADEMIE VED CESKE REPUBLIKY VEREJNA VYZKUMNA INSTITUCE - - - EUR 154 720,80 - - - Identification of novel substrates for ubiquitin ligases involved in cell cycle and cell migration - - - EUR 154 720,80 - - - Czech Republic - - - Research Organisations - - Cancer cells heavily rely on the proteasome-ubiquitin system mediated tuning of proteins stability and proteome composition. Proteasome and ubiquitin ligases targeting drugs are already in use against certain haematological - cancers, and similar inhibitors are currently explored as a possibility for autoimmune diseases and parasite infestation treatment. E3 ubiquitin ligases are the ultimate target for these therapies as they determine specificity in substrate - recognition. It is thus of utmost interest for both basic and translational research to find new ubiquitin ligases essential for cell proliferation, cell migration or cancer progression and couple them with their substrates. In the proposed LIGER - project, we aspire to fuse cutting-edge methods to identify new ubiquitin ligase – substrate pairs. In particular, we will focus on E3 ubiquitin ligases involved in cancer progression and more specifically, in its two crucial aspects - cell growth - and cell migration. To pre-select the ubiquitin ligases for further analysis, we will perform an unbiased screen for ubiquitin ligases that are involved in cell growth and cell migration. To achieve this goal, CRISPR library screening methodology - will be employed. Consequentially, we will purify proteins associated with the selected ubiquitin ligases and identify their potential substrates. Standard biochemical and molecular biology methods will allow us to study in detail the protein - interface between the ubiquitin ligases and their novel substrates and describe the biological function of their degradation. LIGER project will increase our understanding of ubiquitin pathway in physiological and pathological conditions and identify - new potential targets for cancer therapy. - - 2019-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Czech Republic - - - LIGER - - - H2020-MSCA-IF-2016 - - - 752074 - - - - - OSPEDALE SAN RAFFAELE SRL - - - EUR 168 277,20 - - - Investigating the effects of immunogenic chemoradiation in shaping the immune landscape ofesophageal cancers - - - EUR 168 277,20 - - - Italy - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Esophageal carcinoma (EC) is among the top 10 deadliest cancers worldwide. The current standard therapy for ES is neoadjuvant (pre-operative) chemoradiation (NACR) followed by surgery. However, only 30% of patients achieve a - complete pathological response (CPR) and long-term survival. Understanding the mechanisms of response to NACR is hence pivotal to better stratify patients and inform the design of more efficacious therapies. Evidence from some tumors suggests that - NACR is “immunogenic” and stimulates anti-cancer immune responses, which may contribute to the longterm effects of successful treatments. Tumor neo-antigens, generated by somatically mutated cancer genes, have been recently implicated in the - activation of the most efficient anti-tumor T cell response capable of controlling tumor progression, induced by immune checkpoint blockade immunotherapy. This raises the question as to whether clinical responses induced by NACR in a fraction of ECs - may be linked to the stimulation of clinically relevant T cell responses against tumor neoantigens, implying that activating tumor immunity in the non-responding ones may improve clinical responses. Objective of this proof-of-concept study is hence - to address this question through the implementation of a high-throughput platform to assess neoantigen-specific T cell responses in ECs in the course of NACR. - - 2020-02-29, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-SE - Society and Enterprise panel - - - Italy - - - IC_IL_EC_2017 - - - H2020-MSCA-IF-2016 - - - 752698 - - - - - UNIVERSITAT JAUME I DE CASTELLON - - - EUR 170 121,60 - - - Non-Invasive Fluorescence-based Tear Glucose Sensor Integrated to a Smartphone - - - EUR 170 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - The prevalence of diabetes is continuously rising even in low-income economies. Therefore, blood glucose monitoring tools are in high social demand globally. Uninterrupted monitoring of blood glucose is a must in order to keep - the fatal levels of glycated hemoglobin under control and to improve the quality of life for diabetic patients. However, glucose monitoring is compromised by the painful finger pricking about 4-5 times a day to obtain blood samples which leads to - patient non-compliance and hence endangering their lifes. - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - GlucoTear - - - H2020-MSCA-IF-2016 - - - 751249 - - - - - NATIONAL OBSERVATORY OF ATHENS - NATIONAL OBSERVATORY OF ATHENS - - - EUR 1 968 000 - - - Does dust triboelectrification affect our climate? - - - EUR 1 968 000 - - - Greece - Greece - - - Research Organisations - Research Organisations - - The recent IPCC report identifies mineral dust and the associated uncertainties in climate projections as key topics for future research. Dust size distribution in climate models controls the dust-radiation-cloud interactions - and is a major contributor to these uncertainties. Observations show that the coarse mode of dust can be sustained during long-range transport, while current understanding fails in explaining why the lifetime of large airborne dust particles is - longer than expected from gravitational settling theories. This discrepancy between observations and theory suggests that other processes counterbalance the effect of gravity along transport. D-TECT envisages filling this knowledge gap by studying - the contribution of the triboelectrification (contact electrification) on particle removal processes. Our hypothesis is that triboelectric charging generates adequate electric fields to hold large dust particles up in the atmosphere. D-TECT aims to - (i) parameterize the physical mechanisms responsible for dust triboelectrification; (ii) assess the impact of electrification on dust settling; (iii) quantify the climatic impacts of the process, particularly the effect on the dust size evolution - during transport, on dry deposition and on CCN/IN reservoirs, and the effect of the electric field on particle orientation and on radiative transfer. The approach involves the development of a novel specialized high-power lidar system to detect and - characterize aerosol particle orientation and a large-scale field experiment in the Mediterranean Basin using unprecedented ground-based remote sensing and airborne in-situ observation synergies. Considering aerosol-electricity interactions, the - observations will be used to improve theoretical understanding and simulations of dust lifecycle. The project will provide new fundamental understanding, able to open new horizons for weather and climate science, including biogeochemistry, volcanic - ash and extraterrestrial dust research. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Greece - - - D-TECT - - - ERC-2016-COG - - - 725698 - - - - - PANEPISTIMIO THESSALIAS - - - EUR 152 653,20 - - - Exploring MIcrobial networking in pesticides biodeGRAdaTion: novel inocula and biocatalysts for biodepuration of agro-industrial Effluents - - - EUR 152 653,20 - - - Greece - - - Higher or Secondary Education Establishments - - Pesticides constitute priority pollutants for natural resources. Microbes, mostly in the form of microbial consortia are pivotal in the in situ pesticide biodegradation. EMIGRATE aims to investigate the complex interactions - driving the coherence and biodegradation capacity of natural bacterial consortia, and through this, enable the production of biotechnological and bioengineering tools for novel environmental clean-up strategies. A microbial consortium degrading the - fungicide thiabendazole used in fruit-packaging plants will be used as a model. This choice is based on the high biotechnological potential of this consortium considering the environmental risk associated with the use pattern, recalcitrance and - toxicity of this fungicide and the complete lack of information regarding its microbial metabolism. Through its innovative research EMIGRATE will facilitate the re-integration of the fellow to the local and EU research community. Project's objectives - will be achieved through 7 work-packages: WP1 will deal with project management, IPR and results exploitation, WP2 will focus on fellow's training and WP3 on the dissemination and public engagement of project's findings. WP4 will focus on the - in-depth phylogenetic characterization of the bacterial consortium and the identification of the roles of consortium members on pesticide metabolism (Stable Isotope Probing - amplicon sequencing). WP5 will assign wider functional roles to consortium - members, identify key catabolic genes and elucidate the metabolic pathway of the fungicide via a meta-genomics, -transcriptomics, -metabolomics approach. Finally, WP6 and WP7 will exploit the bacterial consortium for isolation of novel - enzymes-biocatalysts and the development of an innovative biological process for the depuration of the relevant agro-industrial effluents. Secondments to academic and industrial partners will be carried out for skill development of the fellow on - isotopic techniques, metabolomics and bioengineering. - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Greece - - - EMIGRATE - - - H2020-MSCA-IF-2016 - - - 749463 - - - - - EBERHARD KARLS UNIVERSITAET TUEBINGEN - EBERHARD KARLS UNIVERSITAET TUEBINGEN - - - EUR 1 499 837 - - - Do early stone tools indicate a hominin ability to accumulate culture? - - - EUR 1 499 837 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Cultural – not genetic – adaptations have allowed humans to colonise the planet. While discovering the roots of human culture has been described as one of the 125 most pressing scientific questions of our time (Science, 2005), - it remains unclear when such forms of culture first arose in our lineage. - - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - STONECULT - - - ERC-2016-STG - - - 714658 - - - - - ARISTOTELIO PANEPISTIMIO THESSALONIKIS - ARISTOTELIO PANEPISTIMIO THESSALONIKIS - PANEPISTIMIO THESSALIAS - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - NETHOOD - - - EUR 758 031 - - - Refiguring the Common and the Political - - - EUR 758 031 - - - Greece - Greece - Greece - United Kingdom - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - - Heteropolitics is a project in contemporary political theory which purports to contribute to the renewal of political thought on the ‘common’ (communities and the commons) and the political in tandem. The common implies a - variable interaction between differences which communicate and collaborate in and through their differences, converging partially on practices and particular pursuits. The political pertains to processes through which plural communities manage - themselves in ways which enable mutual challenges, deliberation, and creative agency. - - - 2020-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Greece - - - HETEROPOLITICS - - - ERC-2016-COG - - - 724692 - - - - - THE UNIVERSITY OF SHEFFIELD - CHALMERS TEKNISKA HOEGSKOLA AB - RANPLAN WIRELESS NETWORK DESIGN LTD - GAPWAVES AB - - - EUR 877 500 - - - indoor small-cell Networks with 3D MIMO Array Antennas - - - EUR 1 309 500 - - - United Kingdom - Sweden - United Kingdom - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - It is predicted that wireless network traffic will increase 1000 times in the next decade. The exponential traffic growth is not uniform across geographical areas and mainly takes place in indoor hot spots. Hence, high - capacity indoor venues represent the biggest network capacity increase challenge. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - United Kingdom - - - is3DMIMO - - - H2020-MSCA-RISE-2016 - - - 734798 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6 - UNIVERSITAET PADERBORN - UNIVERSITE DES SCIENCES ET TECHNOLOGIES DE LILLE - LILLE I - UNIVERSITAET ROSTOCK - UNIVERSITA DEGLI STUDI ROMA TRE - - - EUR 3 219 721,25 - - - Quantum Controlled Ultrafast Multimode Entanglement and Measurement - - - EUR 3 219 721,25 - - - United Kingdom - France - Germany - France - Germany - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Ultrafast light pulses offer the fascinating opportunity to study system dynamics at ultrashort time scales. Trains of ultrafast light pulses also feature a broad frequency comb structure that has been exploited e.g. in high - precision metrology. These characteristics have made ultrafast optics with coherent control techniques a flourishing field in recent years. A rich toolbox has been developed to generate shorter pulses with engineered temporal and spectral properties. - - 2018-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-1-2014 - FET-Open research projects - - - RIA - Research and Innovation action - - - United Kingdom - - - QCUMbER - - - H2020-FETOPEN-2014-2015-RIA - - - 665148 - - - - - UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN - TECHNISCHE UNIVERSITAET WIEN - UNIVERSITY OF GLASGOW - DANMARKS TEKNISKE UNIVERSITET - MEDIZINISCHE UNIVERSITAET WIEN - REGION HOVEDSTADEN - THE ANNA FREUD CENTRE - TELEFONICA INVESTIGACION Y DESARROLLO SA - REACHOUT IRELAND LTD - - - EUR 4 041 770,76 - - - Technology Enabled Adolescent Mental Health - - - EUR 4 041 770,76 - - - Ireland - Austria - United Kingdom - Denmark - Austria - Denmark - United Kingdom - Spain - Ireland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - - There is no health without mental health. 27% of our population are young, and mental health disorders are our leading cause of disability. 50% of mental disorders emerge by 14 yrs, 75% by 24 yrs and, untreated, triple odds of - having a mental health disorder in later life. TEAM’s will build a network of expertise and train a new generation of researchers to deliver more effective, affordable and feasible mental health services for young people. Our interdisciplinary, - international, intersectoral network, balanced in skills, experience and perspectives, will train the next generation of researchers to lead Youth Mental Health (YMH) services into the future. Research objectives focus on key challenges in YMH: - delivering new technologies to support rapid, large-scale, and early assessment, prevention and treatment.TEAM will also deliver policy directions and guidelines for technology-enabled YMH. 2 themes are covered: how can technology a) increase access, - and b) help people to engage more successfully? TEAM will deliver new technology-enabled services that are both accessible and engaging for young people. Our ambitious objectives require individuals with a unique combination of interdisciplinary and - intersectoral skills. TEAM ESRs will receive integrated training across three key areas necessary to fully realise the potential of technology-enabled mental health: Mental Healthcare Delivery - the theories and practice of YMH; Computer science - - core principles in software engineering and technology infrastructures; Interaction Design - theories and methods including co-designing with young people and active engagement with clinicians, social workers, caregivers (e.g. parents) and teachers. - Intersectoral secondments promote interdisciplinary and intersectoral learning and communication, and public engagement and outreach focus on young people, those who play major roles in their lives (e.g. parents and teachers), health care - professionals. - - 2020-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Ireland - - - TEAM - - - H2020-MSCA-ITN-2016 - - - 722561 - - - - - INTENDU LTD - - - EUR 182 509,20 - - - Transforming Brain Rehabilitation - - - EUR 182 509,20 - - - Israel - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Multiple diseases, injuries, and aging, may lead to executive dysfunctions, reducing quality of life. Intendu transforms brain rehabilitation, by introducing a novel platform of video games designed to train executive - functions (EF). The games involve natural body gestures, and are adaptive in real-time to performance. Preliminary results show that training with Intendu’s games is safe, leading to improved cognitive function. Robust evidence for the efficacy of - Intendu’s training program and brain plasticity mechanisms driving functional benefits is required. During this fellowship, and under Dr. Son Preminger’s supervision, founder and CEO of Intendu; and of Drs. Debbie Rand and Doron Freidman, established - researchers in virtual reality (VR), I will (1) receive a unique opportunity to combine my scientific passions – cognitive training and motor learning, video gaming and rehabilitation, basic and applied neuroscience – into one multidisciplinary, - strongly founded field; (2) deepen my knowledge with executive functions; (3) broaden my experience with multiple clinical populations; (4) acquire regulatory and intellectual property legislation knowledge and experience; (5) grow my leadership - skills; (6) gain working experience in a young startup. Building on these critical skills, and on my previous experience as a postdoctoral researcher at the University of California, Berkeley (UCB) and senior scientist at Posit Science Corporation - (PSC), I hope to: (1) lead Intendu’s research with local and international collaborators; manage a network of external research partners; build and manage Intendu’s research team; (2) define scientific foundation for games with Intendu’s product - team; (3) assure research funding; (4) work closely with regulatory consultants to manage regulatory affairs, to clear the program as the first motion-controlled software-based medical treatment for cognitive impairments. Together, this fellowship - will open my best career possibilities. - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-SE - Society and Enterprise panel - - - Israel - - - FBT - - - H2020-MSCA-IF-2016 - - - 753071 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 200 000 - - - Impact of NMDA receptor diversity in sensory information processing - - - EUR 1 200 000 - - - France - France - - - Research Organisations - Research Organisations - - Synaptic variability between neuronal connections is thought to contribute to brain’s remarkable information processing capacities. In the adult brain, the density as well as subunit composition of synaptic NMDA receptors - (NMDARs) varies considerably between synapses and between neurons. Despite the well documented heterogeneity of NMDARs the functional relevance of such diversity is poorly known. In the past, the functional relevance of such NMDAR diversity has been - mostly considered in the context of neuronal development and long-term synaptic plasticity. Model simulations have highlighted that dendritic computations are strongly influenced by synaptic NMDARs densities and biophysical properties. Here I propose - to directly study the consequence of NMDAR diversity in shaping integration properties of single neurons in primary somatosensory cortex (S1). To achieve this I will decompose this broad question into three specific tasks. 1-Assessment of NMDAR - heterogeneity in glutamatergic neurons and study how this variability shapes dendritic integration. 2-Study the impact of NMDARs in signal computation among cortical interneurons. 3-Investigate the functional relationship between endogenous NMDAR - modulators and NMDAR diversity. I plan to use an array of genetic, optogenetic and pharmacological tools in combination with imaging and electrophysiological techniques to achieve the proposed objectives. Importantly, in vivo electrophysiology and - two-photon imaging will be used to assess the functional relevance of NMDARs heterogeneity in single neuron computational strategies during sensory stimulation. I expect to reveal that NMDAR diversity plays a fundamental role in sensory information - processing by tuning the relative recruitment of inhibitory and excitatory neurons during sensory stimuli. This work will provide an original and important data set demonstrating how NMDARs diversity provides cortical neurons with the possibility to - compute complex sensory information. - - 2021-11-30, ongoing project - - - 2016-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - SensoNMDA - - - ERC-2015-STG - - - 678250 - - - - - MEDICAL RESEARCH COUNCIL - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 183 454,80 - - - The structural biology of TrkB-BDNF signalling - - - EUR 183 454,80 - - - United Kingdom - United Kingdom - - - Research Organisations - Higher or Secondary Education Establishments - - Neuronal circuit development involves multiple stages that are regulated by neurotrophic factors. One of the key players, the brain-derived neurotrophic factor (BDNF), is involved in the development and functional modulation - of circuits by promoting neuronal survival, synaptogenesis, synaptic transmission and synaptic plasticity. BDNF acts by binding to the tropomyosin-related kinase receptor B (TrkB), a type-I membrane protein, to trigger downstream signaling. However, - the molecular architecture of this complex and the mechanism of signal propagation across the membrane remain unknown - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - STrkB - - - H2020-MSCA-IF-2015 - - - 709054 - - - - - EBERHARD KARLS UNIVERSITAET TUEBINGEN - EBERHARD KARLS UNIVERSITAET TUEBINGEN - - - EUR 1 497 643 - - - A Silk Road in the Palaeolithic: Reconstructing Late Pleistocene Hominin Dispersals and Adaptations in Central Asia - - - EUR 1 497 643 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In antiquity and the early Middle Ages, a network of trade routes known as the Silk Road connected east Asia and the Мiddle East. The Silk Road was not just an economic link, but also the avenue for cultural and even genetic - exchanges between these regions. Recent genetic discoveries have hinted that such connections might have begun much earlier, during the Pleistocene. The Pleistocene period is of fundamental importance for human history. It is then that our ancestors - evolved and colonised the entire Old World, surviving a suite of major extinction events – and they did so against a dramatic backdrop of ice ages and warmer interglacial phases which substantially altered their habitats. Conquering the extreme - environments of arid central Asia to eventually settle the entire Asian mainland and beyond is one of the most impressive feats in this story. Unfortunately, there are too few known Pleistocene archaeological sites in central Asia to allow us to - piece together when and how this happened. PALAEOSILKROAD will resolve this deficit by surveying central Asian mountain foothills as both corridors for human and animal movements and archives of past climate change. The project will discover new - sites in the Tian Shan, Dzungar, and southern Altai foothills (Kazakhstan) and use them to examine if and how 1) humans were able to survive in the foothills throughout the last glacial cycle (110-11 500 years ago), and 2) periodic advances of - mountain glaciers motivated dispersals, population segmentation, and behavioural adaptations. To address these questions, PALAEOSILKROAD will take an ambitious approach rooted in archaeology and contextualised by palaeoenvironmental reconstruction. - The results of this project will change the way we understand human dispersals on a global scale and the resilience of early humans in the face of environmental challenges, providing a major missing link to explain how Homo sapiens became the only - surviving species of our genus. - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - PALAEOSILKROAD - - - ERC-2016-STG - - - 714842 - - - - - GEANT VERENIGING - BIOBANKS AND BIOMOLECULAR RESOURCES RESEARCH INFRASTRUCTURE CONSORTIUM (BBMRI-ERIC) - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH - CESNET ZAJMOVE SDRUZENI PRAVNICKYCH OSOB - AKADEMIA GORNICZO-HUTNICZA IM. STANISLAWA STASZICA W KRAKOWIE - DAASI INTERNATIONAL GMBH - STICHTING EGI - EISCAT SCIENTIFIC ASSOCIATION - EUROPEAN MOLECULAR BIOLOGY LABORATORY - CONSORTIUM GARR - ETHNIKO DIKTYO EREVNAS TECHNOLOGIAS AE - FORSCHUNGSZENTRUM JULICH GMBH - ISTITUTO NAZIONALE DI ASTROFISICA - INFRAFRONTIER GMBH - INSTRUCT ACADEMIC SERVICES LIMITED - KARLSRUHER INSTITUT FUER TECHNOLOGIE - STICHTING LIBER - MORAVSKA ZEMSKA KNIHOVNA V BRNE - STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN - INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK - RETI SPA - SCIENCE AND TECHNOLOGY FACILITIES COUNCIL - SURFnet bv - UNIVERSIDAD DE CANTABRIA - CARDIFF UNIVERSITY - - - EUR 2 999 892,89 - - - Authentication and Authorisation For Research and Collaboration - - - EUR 2 999 892,89 - - - Netherlands - Austria - Switzerland - Czech Republic - Poland - Germany - Netherlands - Sweden - Germany - Italy - Greece - Germany - Italy - Germany - United Kingdom - Germany - Netherlands - Czech Republic - Netherlands - Poland - Italy - United Kingdom - Netherlands - Spain - United Kingdom - - - Other - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Other - Other - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The goal of AARC2 is to design an AAI framework to develop interoperable AAI, to enable researchers to access the whole research and infrastructure service portfolio with one login. AARC2's objectives are: - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.3."> - - - EINFRA-22-2016 - User-driven e-infrastructure innovation - - - RIA - Research and Innovation action - - - Netherlands - - - AARC2 - - - H2020-EINFRA-2016-1 - - - 730941 - - - - - WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER - WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER - FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG - - - EUR 1 499 875 - - - Structure-Property Relations in Aqueous Foam and Their Control on a Molecular Level - - - EUR 1 499 875 - - - Germany - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Foams are of enormous importance as we find them in many technological relevant applications and food products. Foams as hierarchical materials are dominated by the arrangement and distri-bution of gas bubbles on a macroscopic - scale, as well as by thickness and composition of lamella on a mesoscopic scale. Liquid-gas interfaces are, however, the building block of foam with over-whelming importance as their molecular properties easily dominate hierarchical elements on - larger length scales. In order to formulate foam with specific properties, its structure must be controlled at the molecular level of a liquid-gas interface. Here, the molecular composition, molecular order and interactions such as electrostatics - dominate, and thus must be addressed with molecular level probes that can provide access to both interfacial solvent and solute molecules. Specifically, mo-lecular structures of aqueous interfaces can be modified by adding different mixtures of - surface active molecules such as proteins, surfactants and polyelectrolytes, and by adjusting electrolyte properties. This is achieved by varying pH, introducing ions at different ionic strengths as well as by changing viscosities. Such model systems - will be characterized with nonlinear optical spectroscopy amongst other surface sensitive probes. The gained information will be used to deduce properties of structures on larger length scales such as lamella, bubbles in a bulk liquid - as a - precursor of foam - and finally macroscopic foam. For each length scale, experiments will be performed to gain access to molecular buildings blocks at liquid-gas interfaces and their effects on other hierarchical elements. These experiments thus - provide essential information on foam stability and bubble coalescence, they can be used to verify structure-property relationships and to advance our understanding of foam on a molecular basis. - - 2020-02-29, ongoing project - - - 2015-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - SUPERFOAM - - - ERC-2014-STG - - - 638278 - - - - - NORSK INSTITUTT FOR LUFTFORSKNING STIFTELSE - NORSK INSTITUTT FOR LUFTFORSKNING STIFTELSE - - - EUR 2 800 000 - - - Camera Observation and Modelling of 4D Tracer Dispersion in the Atmosphere - - - EUR 2 800 000 - - - Norway - Norway - - - Research Organisations - Research Organisations - - COMTESSA will push back the limits of our understanding of turbulence and plume dispersion in the atmosphere by bringing together full four-dimensional (space and time) observations of a (nearly) passive tracer (sulfur - dioxide, SO2), with advanced data analysis and turbulence and dispersion modelling. - - 2020-10-31, ongoing project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Norway - - - COMTESSA - - - ERC-2014-ADG - - - 670462 - - - - - THE RESEARCH COMMITTEE OF THE TECHNICAL UNIVERSITY OF CRETE - ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON - TECHNOLOGIKO PANEPISTIMIO KYPROU - THE CYPRUS INSTITUTE - AEA s.r.l. - THE UK INTELLIGENT SYSTEMS RESEARCH INSTITUTE LIMITED - Elgama-Elektronika - IDEA SRL - BRUNEL UNIVERSITY LONDON - EXERGY LTD - - - EUR 958 500 - - - Smart Grids Energy management Staff - - - EUR 958 500 - - - Greece - Greece - Cyprus - Cyprus - Italy - United Kingdom - Lithuania - Italy - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Smart grid is a dynamically interactive real-time infrastructure concept that encompasses the many visions of diverse energy system stakeholders. The Smart Grid is integrating the electrical and information technologies in - between any point of generation and any point of consumption. The main objective of the project is to fully analyze all aspects of smart grids targeting in the improvement of reliability, mitigation of security risks, increase load shaping and energy - efficiency, optimal integration and generation-consumption matching as well as smart monitoring and control. - - 2019-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Greece - - - SMART GEMS - - - H2020-MSCA-RISE-2014 - - - 645677 - - - - - OREBRO UNIVERSITY - - - EUR 1 255 680 - - - Training a new breed of interdisciplinary researchers to respond to the opportunities and challenges of ageing - - - EUR 2 511 360 - - - Sweden - - - Higher or Secondary Education Establishments - - The ageing population is one of Europe’s and the world’s grand challenges for the 21st century. How to cope with populations that are living ever longer and understanding the processes and means of tackling and benefitting - from such populations has already been studied in great detail. However, the studies have mostly been independent, in often almost unrelated areas. - - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2016 - Co-funding of regional, national and international programmes - - - MSCA-COFUND-DP - Doctoral programmes - - - Sweden - - - NEWBREED - - - H2020-MSCA-COFUND-2016 - - - 754285 - - - - - INSTITUT FRANCAIS DES SCIENCES ET TECHNOLOGIES DES TRANSPORTS, DE L'AMENAGEMENT ET DES RESEAUX - PHI-MECA ENGINEERING - AALBORG UNIVERSITET - COWI AS - BUNDESANSTALT FUER MATERIALFORSCHUNG UND -PRUEFUNG - GUD CONSULT GMBH - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - NEOSTRAIN SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA - - - EUR 3 161 112,84 - - - Innovation and Networking for Fatigue and Reliability Analysis of Structures - Training forAssessment of Risk - - - EUR 3 161 112,84 - - - France - France - Denmark - Denmark - Germany - Germany - Switzerland - Poland - - - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - INFRASTAR aims to develop knowledge, expertise and skill for optimal and reliable management of structures. The generic methodology will be applied to bridges and wind turbines in relation to fatigue offering the opportunity - to deal with complementary notions (such as old and new asset management, unique and similar structures, wind and traffic actions) while addressing 3 major challenges: 1/advanced modelling of concrete fatigue behaviour, 2/new non destructive testing - methods for early aged damage detection and 3/probabilistic approach of structure reliability under fatigue. Benefit of cross-experience and inter-disciplinary synergies will create new knowledge. INFRASTAR proposes innovative solutions for civil - infrastructure asset management so that young scientists will acquire a high employment profile in close dialogue between industry and academic partners. - - 2020-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - France - - - INFRASTAR - - - H2020-MSCA-ITN-2015 - - - 676139 - - - - - UNIVERSITY OF STRATHCLYDE - - - EUR 183 454,80 - - - Models and Algorithms for Graph centrality grounded on Nonlinear Eigenvalues Techniques - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Models and Algorithms for Graph centrality grounded on Nonlinear Eigenvalues Techniques - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - MAGNET - - - H2020-MSCA-IF-2016 - - - 744014 - - - - - DEUTSCHES FORSCHUNGSZENTRUM FUR KUNSTLICHE INTELLIGENZ GMBH - Eidgenössische Technische Hochschule Zürich - UNIVERSITAET STUTTGART - UNIVERSITY COLLEGE LONDON - KOZEP-EUROPAI EGYETEM - ISTITUTO PER L'INTERSCAMBIO SCIENTIFICO - CONSIGLIO NAZIONALE DELLE RICERCHE - FONDAZIONE BRUNO KESSLER - - - EUR 3 450 625 - - - Bringing CItizens, Models and Data together in Participatory, Interactive SociaL EXploratories - - - EUR 4 206 875 - - - Germany - Switzerland - Germany - United Kingdom - Hungary - Italy - Italy - Italy - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Research Organisations - - We propose visionary research to develop modeling, computational, and ICT tools needed to predict and influence disease spread and other contagion phenomena in complex social systems. To achieve non-incremental advances we - will combine large scale, realistic, data-driven models with participatory data-collection and advanced methods for Big Data analysis. In particular we will go beyond the one-dimensional focus of current approaches tackling one aspect of the problem - at a time. We will interconnect contagion progression (e.g. epidemics) with social adaptation, the economic impact and other systemic aspects that will finally allow a complete analysis of the inherent systemic risk. We will develop models dealing - with multiple time and length scales simultaneously, leading to the definition of new, layered computational approaches. Towards policy impact and social response we will work to close the loop between models, data, behavior and perception and - develop new concepts for the explanation, visualization and interaction with data and models both on individual and on collective level. We will cast the fundamental advances into an integrated system building on widely accepted open ICT technologies - that will be used and useful beyond the project. As a tangible ICT outcome directed at facilitating the uptake and impact of the project, we will implement “Interactive Social Exploratories” defined as interactive environments which act as a - front-end to a set of parameterizable and adjustable models, data analysis techniques, visualization methods and data collection frameworks. In summary, we aim to (1) produce fundamental theoretical, methodological and technological advances (2) mold - them into a broadly usable ICT platform that will be a catalyst for producing, delivering, and embedding scientific evidence into the policy and societal processes and (3) evaluate the system empirically with policy makers and citizens focusing on - the concrete problem of epidemic spreading. - - 2017-12-31, closed project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.2."> - - - FETPROACT-1-2014 - Global Systems Science (GSS) - - - RIA - Research and Innovation action - - - Germany - - - CIMPLEX - - - H2020-FETPROACT-2014 - - - 641191 - - - - - UNIVERSITY OF LEEDS - - - EUR 195 454,80 - - - Ti-Graphene Bone Tissue Template Engineering - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The BonE-GraphT aims to develop a new approach, based on bone template engineering using which the entire load-bearing structure might be possible to regenerate for replacing the damaged bone. The proposed approach, once - developed, will be possible to align with the tissue-engineering bio-reactor technology for in-theatre use, which may be able to meet the demand for current shortage in treating the damaged load-bearing long bones (e.g. tibia femur) in trauma, - osteoporotic bones and other bone defects. Within my research I am going to develop a new biomaterial: Calcium Phosphate coated graphene composite on porous Ti-alloy substrate via pulsed laser deposition techniques for enabling biocompatibility via - osteoconductive process, promoted via progenitor stem cells. For research training as an orthopaedic materials engineer within which I aim to solve orthopaedic defects as a global problem I will deal with the following Research Training Activities - (RTAs); i) Ti-alloy based graphene/calcium phosphate materials processing using femtosecond PLD; ii) Characterization of bio-active materials surface; iii) Characterization of cell cultivation, toxicity, attachment and mineralization; iv) Design of - model bone structure. - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - BonE-GraphT - - - H2020-MSCA-IF-2016 - - - 752297 - - - - - THE RESEARCH COMMITTEE OF THE TECHNICAL UNIVERSITY OF CRETE - - - EUR 164 653,20 - - - Enhancing our Understanding of Earth’s Land Surface InteractiONs at Multiple Scales Utilising Earth Observation - - - EUR 164 653,20 - - - Greece - - - Higher or Secondary Education Establishments - - "Today, particularly so in the face of climate change and the need to meet global food and water security requirements, there is an urgent need for a better understanding of natural processes in the Earth System and of land - surface interactions (LSIs). The recent rapid developments in Earth Observation (EO) technology (new satellites launched, drones) demonstrate the real need and the true potential of this technology in this direction. - - - 2019-10-01, ongoing project - - - 2017-10-02 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Greece - - - ENviSION-EO - - - H2020-MSCA-IF-2016 - - - 752094 - - - - - UNIVERSITAET POTSDAM - GCF - GLOBAL CLIMATE FORUM EV - UNIVERSITAET STUTTGART - INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK - ISTITUTO PER L'INTERSCAMBIO SCIENTIFICO - SCUOLA IMT (ISTITUZIONI, MERCATI, TECNOLOGIE) ALTI STUDI DI LUCCA - CHALMERS TEKNISKA HOEGSKOLA AB - ATOS SPAIN SA - CONSORZIO TOP-IX - TORINO E PIEMONTE EXCHANGE POINT - THE COSMO COMPANY SAS - DIALOGIK GEMEINNUETZIGE GESELLSCHAFT FUER KOMMUNIKATIONS- UND KOOPERATIONSFORSCHUNG mbH - - - EUR 4 469 662,50 - - - Center of Excellence for Global Systems Science - - - EUR 4 469 662,50 - - - Germany - Germany - Germany - Poland - Italy - Italy - Sweden - Spain - Italy - France - Germany - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - - Global Systems Science – GSS – is an emerging research field focused on the risks and opportunities involved in global coordination problems. Examples of global systems include the internet, financial markets, intellectual - property rights, global energy use and others. - - - 2018-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.3."> - - - EINFRA-5-2015 - Centres of Excellence for computing applications - - - RIA - Research and Innovation action - - - Germany - - - COEGSS - - - H2020-EINFRA-2015-1 - - - 676547 - - - - - UNIVERSITY OF SURREY - - - EUR 183 454,80 - - - Vulnerability and risk assessment of transportation systems of assets (SoA) exposed to geo-hazards - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Available risk assessment frameworks typically consider individual assets of the transportation infrastructure, exposed to just one hazard and they neglect changes in the asset performance during its life. However, assets - exist in systems (SoA) and they are usually exposed to multiple hazards, whilst their performance changes due to deterioration or improvements. Also, the vast majority of existing studies is qualitative and focuses on bridges. Hazards, such as ground - movements, debris flow, earthquakes and floods are major threats to infrastructure around the world, causing significant physical and socio-economic losses. Thus, reliable assessment of the vulnerability and the associated risks of infrastructure - subjected to critical hazards is of paramount importance toward resilient transportation networks. TRANSRISK aims to fill these acknowledged gaps and provide advanced vulnerability assessment of critical transportation SoA subjected to diverse geo- - and climatic hazards with focus on geotechnical effects, taking into account the SoA performance changes during their life. In this context, advanced numerical models of representative SoA subjected to critical combinations of hazard effects will be - generated and validated based on recorded events. Novel adaptable vulnerability models will be produced for as-built, deteriorated (e.g. past hazards) and improved (e.g. strengthened) SoA. These models will be applied to selected parts of a highway - and/or railway network in Europe to estimate the risk and associated losses due to recorded hazards as a means to enable the unbiased allocation of resources in decision-making and disaster management. The research results will provide a better - understanding of the response of critical SoA and a rational link of the individual asset response to the network performance. The outcomes will also benefit stakeholders and owners of transportation networks in line with the EU strategy on critical - infrastructure protection. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - TRANSRISK - - - H2020-MSCA-IF-2016 - - - 746298 - - - - - THE RESEARCH COMMITTEE OF THE TECHNICAL UNIVERSITY OF CRETE - - - EUR 152 653,20 - - - PArtial Differential Equation model-based COntrol of Traffic flow - - - EUR 152 653,20 - - - Greece - - - Higher or Secondary Education Establishments - - A new framework is introduced for control and estimation of traffic flow in freeways and arterials. In the new methodology, feedforward and feedback control designs are developed, based on continuum in time and space - traffic-flow models, which assign to the traffic flow the desired shape, with an a priori prescribed convergence rate and for any initial traffic profile. The novel control and estimation algorithms require minimum amount of information since they - utilize measurements at the entries and exits of the freeway and arterial links. The designs are accompanied with tools for verification that are introduced, which provide quantified actual performance guarantees and robustness margins of the - proposed algorithms. The methodology is validated in simulation, using fictitious and real data of traffic, and/or in a real traffic system. - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Greece - - - PADECOT - - - H2020-MSCA-IF-2016 - - - 747898 - - - - - UNIVERSITE DE PERPIGNAN - - - EUR 185 076 - - - Study of the environmental impact of insecticides by metabolomic foot-printing approach - - - EUR 185 076 - - - France - - - Higher or Secondary Education Establishments - - The European Directive in 1998 led to the increasing use of biological insecticides such as cry proteins produced by the bacterium Bacillus thuringiensis israelensis (Bti) that kill mosquito larvae after being ingested. - Considering the interest in Bti as more environmentally sustainable biocide, it is important to examine environmental fate and impact of Bti especially taking into account the need of this information to fulfil the REACH criteria. Chandrashekhar (PhD - 2014, North Maharashtra University, India) will employed an innovative 'Environmental Metabolic Footprinting' approach, at the University of Perpignan via Domitia, France and participate in a multidisciplinary project that spans the interface between - chemistry and biology. To dynamically characterize biomarkers of Bti pollution found among metabolites issued from the sediment matrix meta-metabolome will require him to develop and optimize detection protocols using LC-MS platform. In addition, - metabarcoding approach will allow to understand microbial community responses to the Bti pollution. Emphasis will be placed on better standardisation, data interpretation and evaluation that will build confidence in the value of “omics technologies – - this being essential to increase their (regulatory) use. Through secondment to University Joseph Fourier, Grenoble he will deepen his knowledge base by evaluating fate of Bti in the sediment through cutting edge biological analysis tools. Taken - together, these activities will advance our understanding of environmental risks associated with Bti, and pave the way for the development and adaptation to new environmental monitoring tool. EnvFate will thus increase the European research - visibility to promote sustainable development, ensure the protection of environment, one of the priority areas of the H2020 program. Moreover, through the planned training and mentoring activities, Chandrashekhar will develop in to an outstanding - early career researcher of great potential. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - EnvFate - - - H2020-MSCA-IF-2016 - - - 746656 - - - - - INSTITUT CURIE - INSTITUT CURIE - - - EUR 150 000 - - - Precision confiner for mechanical cell activation - - - EUR 150 000 - - - France - France - - - Research Organisations - Research Organisations - - In tissues, cells have their physical space constrained by neighbouring cells and extracellular matrix. In the PROMICO ERC project, our team proposed to specifically address the effect of physical confinement on normal and - cancer cells that are dividing and migrating, using new pathophysiologically relevant in vitro approaches based on innovative micro-fabrication techniques. One of the devices we developed was meant to quantitatively control two key parameters of the - cell environment: its geometry and its surface chemical properties. The main technical breakthrough was achieved using micro-fabricated elastomeric structures bound to a hard substrate (Le Berre Integrative Biology, 2012). The method led to important - fundamental discoveries in cell biology (Lancaster Dev Cell 2013, Le Berre PRL 2013, Liu Cell 2015, Raab Science 2016). In part based on our findings, the notion that confinement is a crucial parameter for cell physiology has spread through the cell - biology. Based on this, our idea is that cell confinement could be used as a powerfull cell conditioning technology, to change the cell state and offer new opportunities for fundamental research in cell biology, but also in cell therapies and drug - screening. However, our current method to confine cells is not adapted to large scale cell conditioning applications, because the throughput and reliability of the device is still too low and because the recovery of cells after confinement remain - poorly controlled. It is thus now timely to develop a robust and versatile cell confiner adapted to use in any cell biology lab, in academy and in industry, with no prior experience in micro-fabrication. Achieving this goal involves a complete change - of technology compared to the ‘homemade’ PDMS device we have been using so far. We will also perform proofs of concept of its use for its application in cell based therapies, such as cancer immunotherapy, by testing the possibility to mechanically - activate dendritic cells. - - 2018-11-30, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - France - - - ACTICELL - - - ERC-2016-PoC - - - 755347 - - - - - KING'S COLLEGE LONDON - - - EUR 183 454,80 - - - Legal Cultures and Literary Trials in the Age of Goethe. The Vehmic Court Motif in Interdisciplinary and Comparative Perspective - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The project aims at a first systematic and in-depth investigation of the motif of the Vehmic Court – a medieval secret tribunal – in German literature of the late 18th and early 19th centuries. Despite the remarkable - popularity of the subject, little research has yet been conducted to define the epistemological framework of its development. By dismissing the Vehme as a “trivial” trope, scholars have not grasped its broader relevance for the culture of the Saddle - Period around 1800, an age of transitions and paradigm shifts in society and politics, but also in literature, historiography and the legal system. - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - VehmeLit - - - H2020-MSCA-IF-2016 - - - 744413 - - - - - ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOCIENCIAS - ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOCIENCIAS - - - EUR 150 000 - - - A metabolism-based prognostic biomarker for prostate cancer - - - EUR 150 000 - - - Spain - Spain - - - Research Organisations - Research Organisations - - Prostate cancer (PC) is the most prevalent tumour type among men. The fraction of patients that exhibit disease recurrence can reach 15% and they face an uncertain future, since this type of tumour is prone to resist to - subsequent therapeutic strategies. Current guidelines for treatment of PC include prostatectomy or radiotherapy as first line therapy for localized disease, and chemical castration followed by chemotherapy for recurrent PC. The lack of capacity to - identify therapy responders vs. escapers in PC is one of the sources for its important mortality. The challenge resides in providing clinicians with a robust and affordable biomarker that informs about the success of first line therapy in localised - PC, and that allows them to employ more intensive therapeutic strategies in high-risk patients. - - 2018-11-30, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Spain - - - MetaboMARKER - - - ERC-2016-PoC - - - 754627 - - - - - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - - - EUR 150 000 - - - Treatment of liver disease and cancer prevention - - - EUR 150 000 - - - France - France - - - Research Organisations - Research Organisations - - Advanced liver disease and cancer is the only major cause of death still increasing each year. Major causes include hepatitis B and C viruses, alcohol and non-alcoholic fatty liver disease/steatohepatitis (NAFLD/NASH). A major - contributing factor to the increasing incidence and mortality of liver disease is the staggering rise in obesity. The absence of effective therapeutic options for NAFLD/NASH, advanced liver disease and cancer contribute to the poor prognosis and the - high cost associated with patient care. We have established a tractable and clinically relevant human cell-based model system in which viral infection, ethanol or free fatty acids induce a clinical gene expression signature robustly predicting liver - disease progression and long-term HCC risk in cirrhotic patients. Using this model we identified compounds as HCC chemopreventive agents. Aiming to evaluate these compounds for future clinical development and potential commercialization we will - perform proof-of-concept studies in state-of-the-art mouse models for NASH and hepatocarcinogenesis. Specifically we will assess the therapeutic effect on liver inflammation, steatosis, fibrosis and HCC development and investigate its safety in - long-term administration. With the completion of this program we expect to obtain a robust proof-of-concept data package as a first- or best-in-class compound for treatment of chronic liver disease and prevention of HCC. - - 2018-11-30, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - France - - - PRELICAN - - - ERC-2016-PoC - - - 755460 - - - - - EUROPEAN MOLECULAR BIOLOGY LABORATORY - EUROPEAN MOLECULAR BIOLOGY LABORATORY - - - EUR 2 499 995 - - - Dissecting quantitative traits and their underlying genetic interactions via systematic genome editing - - - EUR 2 499 995 - - - Germany - Germany - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Despite the ubiquity of genome sequence data, unravelling the contributions of genetic variation to phenotypic diversity remains one of the greatest challenges in genomics. This is partly due to our very limited knowledge of - how multiple variations combine to create phenotypes. There is a clear need for a systematic, perturbation-based approach to study the phenotypic consequences of genetic variants in different genomic and environmental contexts. Previous efforts have - primarily used loss-of-function or overexpression approaches, but it is known that subtle, naturally occurring variants have the most relevance for complex, quantitative traits. Our proposal aims to dissect these effects by systematically engineering - and functionally profiling naturally occurring single-nucleotide variants (SNVs) and small insertion/deletion polymorphisms (indels) in the S. cerevisiae species in three diverse genetic backgrounds. To generate such an unprecedented collection, we - will apply a high-throughput CRISPR approach that allows rapid isolation of sequence-verified strains. DNA barcodes integrated into the genome of each strain will enable pooled, competitive growth, which will reveal how variants modulate fitness as a - function of environment and genetic background. We will test our collection for pairwise and higher order interactions, assay their impact on cellular processes and dissect pleiotropic roles of highly connected genes. Our work will circumvent the key - limitations in current high-throughput genome editing screens and enable the largest interrogation of the functional impact of genetic variation in different environmental and genetic contexts to date. The combined insights and tools generated by our - work will aid in developing predictive models of the effects of genetic variation within specific environmental and biological contexts, providing guiding principles for understanding the consequences of human genetic variation. - - 2022-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - SystGeneEdit - - - ERC-2016-ADG - - - 742804 - - - - - INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM - INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM - - - EUR 2 499 074 - - - video-rate holographic projection by novel meta-materials - - - EUR 2 499 074 - - - Belgium - Belgium - - - Research Organisations - Research Organisations - - Today, despite many efforts by researchers world-wide, there are no holographic projectors that allow video-rate electronically controlled projection of complex holograms. Optically re-write-able holograms exist, but they are - too slow; Acoustically-formed holograms can be switched fast but the image complexity is very limited. We identify the essential roadblock as one that we intend to clear by a breakthrough innovation coming from a combination of electronics, optics - and material science. - - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Belgium - - - VIDEO HOLOGRAPHY - - - ERC-2016-ADG - - - 742299 - - - - - UNIVERSIDAD DE SALAMANCA - - - EUR 170 121,60 - - - Role of bacterial cellulases in the transition from free living to root endophytes in rapeseed crops and in the design of efficient biofertilizers - - - EUR 170 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - One of the main challenges for humanity during next decades will be to increase food production while using scarce resources and protecting the environment, being therefore one of the priorities of the European Program - “Horizon 2020”. Plant’s productivity can be enhanced by the activity of Plant Growth-Promoting (PGP) bacteria, applied in agricultural fields as biofertilizers or plant probiotics, constituting an environmental friendly manner to increase crop - yields. Biofertilizers have been applied in agriculture during decades, but in many cases bacteria which showed great PGP potential in lab conditions, fail when applied in natural soils, probably because they are out-competed by the soil native - microbial populations or they are unable to adapt to the new environmental conditions. - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - BIOFERTICELLULASER - - - H2020-MSCA-IF-2016 - - - 750795 - - - - - RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN - RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN - - - EUR 1 277 830 - - - A Unified Framework of Business Cycles and Household Portfolios: Income Risks, Asset Liquidity, and Inequality - - - EUR 1 277 830 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Households face large idiosyncratic income risks and use their wealth to self insure. In doing so, they make portfolio choices we can summarize grosso modo as choices between liquid (safe and nominal) and illiquid (risky and - real) assets. These choices have the potential to create strong aggregate repercussions as investments in real assets create an immediate demand for goods, while liquid nominal savings only when someone else uses the funds to invest or consume. As a - result, portfolio choices are key for economic dynamics and important for the propagation of monetary and fiscal policy. Moreover, household portfolio positions and the liquidity of assets itself become an important determinant of aggregate savings - and investment. Yet, they are widely disregarded in standard business cycle models today. - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - LiquidHouseCycle - - - ERC-2016-COG - - - 724204 - - - - - INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE - INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE - - - EUR 1 965 624,99 - - - Directed crop breeding using jumping genes - - - EUR 1 965 624,99 - - - France - France - - - Research Organisations - Research Organisations - - The rapidly changing climate puts commonly used crop plants under strong pressure. It is therefore essential to develop novel breeding technologies to rapidly enhance crops to better withstand newly emerging stresses. - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - France - - - BUNGEE - - - ERC-2016-COG - - - 725701 - - - - - AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH - UNIVERSITE CATHOLIQUE DE LOUVAIN - ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON - INSTITUT FUR PFLANZENKULTUR EK - ARISTOTELIO PANEPISTIMIO THESSALONIKIS - UNIVERSITEIT GENT - - - EUR 2 732 872,32 - - - “MICROMETABOLITE” – Research Training Network on the Microbial Enhancement of Bioactive Secondary Metabolite Production in Plants - - - EUR 2 732 872,32 - - - Austria - Belgium - Greece - Germany - Greece - Belgium - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Plant-derived natural products or, more specifically, plant secondary metabolites are backbones of today’s pharmaceutical and cosmeceutical industry. Plant-associated microorganisms have been implicated an important role in - sustaining plant growth and, through inducing or influencing synthesis pathways, in the production of plant secondary metabolites. MICROMETABOLITE aims at exploring the plant-associated microflora for improving the production of bioactive secondary - plant metabolites that are of high value for industrial applications. The network will focus on members of the Boraginaceae plant family including Lithospermum and Alkanna species, which produce the naphtoquinones shikonin and alkannin derivatives - (A/S). These plants are used for the production of several pharmaceutical and cosmeceutical preparations that are already on the market or in the final stages of development. Specifically, we will analyse relationships between the content of A/S or - other secondary metabolites, the plant genotype, and the plant-associated microflora. Further, we will explore in which ways microorganisms beneficially influence metabolite production, and we will establish novel production systems, enabling that - raw materials for industrial applications can be cultivated under Good Agricultural Practices (GAP). - - 2021-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Austria - - - MICROMETABOLITE - - - H2020-MSCA-ITN-2016 - - - 721635 - - - - - FONDATION POUR L INSTITUT DE HAUTES ETUDES INTERNATIONALES ET DU DEVELOPPEMENT - FONDATION POUR L INSTITUT DE HAUTES ETUDES INTERNATIONALES ET DU DEVELOPPEMENT - - - EUR 2 475 275 - - - The Paths of International Law: Stability and Change in the International Legal Order - - - EUR 2 475 275 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - International law erects high hurdles for change – typically unanimity or a uniformity of practice of states – and this high threshold has provoked much criticism for hindering the pursuit of justice, the provision of public - goods, and the democratic revision of political choices. Yet in different areas, such as international criminal law or the law of international organizations, international law has in recent times undergone more rapid change than the traditional - picture would allow, and often in informal ways that do not fit classical categories. However, this greater dynamism has found little sustained attention in scholarship so far. - - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Switzerland - - - PATHS - - - ERC-2016-ADG - - - 740634 - - - - - GOETEBORGS UNIVERSITET - GOETEBORGS UNIVERSITET - - - EUR 2 000 000 - - - Ultrafast Molecular Structural Dynamics - - - EUR 2 000 000 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Chemical reactions in solution are strongly influenced by femtosecond solvent-solute dynamics. Likewise, proteins provide specific environments to control the outcome of substrate reactions. The molecular understanding of - these effect are currently poorly developed. - - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Sweden - - - MolStrucDyn - - - ERC-2016-COG - - - 725642 - - - - - UNIVERSITAET INNSBRUCK - UNIVERSITAET INNSBRUCK - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - - - EUR 1 496 664,30 - - - Innovative Strategies towards Halogenated Organic Molecules: From Reaction Design to Application in Drug Synthesis - - - EUR 1 496 664,30 - - - Austria - Austria - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Halogenated arenes and heteroarenes have become essential structural motifs of the pharmaceutical industry to create novel drugs against bacterial infections and cancer, and constitute highly valuable functional units in - chemistry. Current methods for the installation of carbon-halogen bonds lack efficiency, selectivity, and practicability within the complex molecular setting of drug development processes. These restrictions prevent many potential drugs from being - synthesized in a time- and cost-efficient manner. - - 2022-01-31, ongoing project - - - 2017-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Austria - - - HALODRUGSYN - - - ERC-2016-STG - - - 714049 - - - - - UNIVERSITAETSKLINIKUM HAMBURG-EPPENDORF - - - EUR 171 460,80 - - - Vision at a second glance - how memories interact with and depend on information processing in the human visual cortex - - - EUR 171 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - The cognitive faculties of memory and vision are heavily intertwined. Therefore, understanding the brain processes supporting these faculties critically depends on insights into vision-memory interactions. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - VisionAtSecondGlance - - - H2020-MSCA-IF-2016 - - - 753441 - - - - - ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS - NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - PANEPISTIMIO PATRON - PANEPISTIMIO THESSALIAS - - - EUR 258 750 - - - Invitation to Researchers’ Night 2016-2017 HEllas - - - EUR 273 150 - - - Greece - Greece - Greece - Greece - Greece - - - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - IRENE project concerns the organization of the most successful Researchers’ Night (RN) events in Greece as yet. 5 prestigious research organisations join forces and organize RN events in the most important Greek cities - covering the country from north to south. - - 2017-11-30, closed project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.5."> - - - MSCA-NIGHT-2016 - European Researchers' Night - - - CSA - Coordination and support action - - - Greece - - - IRENE - - - H2020-MSCA-NIGHT-2016 - - - 722935 - - - - - FONDATION POUR L INSTITUT DE HAUTES ETUDES INTERNATIONALES ET DU DEVELOPPEMENT - - - EUR 117 137,25 - - - Women's Economic Rights and Cultural Difference: Defining Development for the Middle East - - - EUR 117 137,25 - - - Switzerland - - - Higher or Secondary Education Establishments - - This research focuses on tensions between discourses of multiculturalism and women’s economic rights and the processes in which they arise in development institutions and programs. While the multidisciplinary literature on - development unpacks public declarations by development institutions and studies the local implementation of development programs, it evades two crucial questions: conditions of agency formation and inequality in institutional processes, and the role - assumptions about cultural difference play in development paradigms. This research fills these gaps by exploring how issues of women’s economic rights and notions of cultural difference are negotiated inside development institutions and reflected in - their programs. The research deploys two data collection strategies, longitudinal content and discourse analysis of relevant development reports and interviews with gender experts with work experience on the Middle East. It will be conducted at the - Gender Centre of the Graduate Institute of International and Development Studies, under the supervision of Professor Elisabeth Prügl, a best fit for the project given the rich array of gender and development scholarship at the Centre, its established - networks with the multilateral actors in Geneva and beyond, and the two scholars’ mutual interests in the area of gender expertise and gender equality. It is an interdisciplinary project, informed by relevant studies in the fields of anthropology, - sociology and political science, and has significant potential to contribute development studies and feminist political economy. It builds on the researcher’s experience in the field of gender and development, the Middle East and transnational - networks. It expands her research to international gender experts in development; grows her expertise on the Middle East; and enlarges her fieldwork scope to Europe. The training, networking and publication prospects put her on a firm path toward - professorship. - - 2018-09-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - WoRD-DoME - - - H2020-MSCA-IF-2016 - - - 746133 - - - - - UNIVERSITAT AUTONOMA DE BARCELONA - - - EUR 170 121,60 - - - Reactivation of the Fanconi anemia-BRCA pathway in cells carrying patient-derived missense mutations: finding a drug to cure Fanconi anemia - - - EUR 170 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - Fanconi anemia (FA) is a genetic disease characterized by bone marrow failure, malformations and cancer predisposition. Currently, there is no cure for FA and life expectancy is 29 years. In addition, FA cells are - hypersensitive to DNA coss-linking agents used in chemotherapy making cancer treatment difficult. The genetic cause of FA is heterogeneous, involving at least 19 different FA genes (FANCA, B, C, D1/BRCA2, D2, E, F, G, I, J, L, M, N, O, P, Q, R, - S/BRCA1 and T) all interacting in a common DNA repair pathway (the FA/BRCA pathway). FANCD2 ubiquitination and localization at sites of DNA damage is a key step in the activation of the FA pathway and it is used to assess its functionality. - Importantly, mutations in FANCA are the most prevalent, accounting for 60-85% of FA cases. FANCA missense mutants mislocalize FANCA to the cytoplasm instead of the nucleus, thereby inactivating the FA pathway. However, FANCA mutants may retain its - functionality, suggesting that correction of the subcellular mislocalization of FANCA missense mutants may be an effective way to reactivate the FA/BRCA pathway in these patients. In this application, we propose to conduct a study to develop a system - to promote nuclear localization of FANCA missense mutants and evaluate its impact on the activation of the FA/BRCA pathway. This study will yield valuable information about the molecular mechanisms that determine FANCA subcellular localization and - pathogenicity of the mutations. In a second part of the project, we will use an unbiased high-throughput approach to screen for drugs that can reactivate the FA/BRCA pathway in cells containing FANCA missense mutations, independently of their - mechanism of action. In summary, using a combination of targeted and unbiased approaches, we aim at finding the first drug with the potential to cure FA in a large subset of patients. Personalized medicine-based therapies may be the only option to - cure FA and other highly heterogeneous genetic diseases. - - 2019-03-06, Grant Agreement terminated - - - 2017-03-07 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - FANCODRUG - - - H2020-MSCA-IF-2015 - - - 703521 - - - - - THE RESEARCH COMMITTEE OF THE TECHNICAL UNIVERSITY OF CRETE - MASSACHUSETTS INSTITUTE OF TECHNOLOGY - - - EUR 176 408,10 - - - Mechanistic Microscale Approach to the Microbial Degradation of Oil-Droplets in Subsea Crude Oil Releases - - - EUR 176 408,10 - - - Greece - United States - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In oligotrophic marine ecosystems, the natural or accidental release of crude oil marks the beginning of a season of feast for indigenous microbial consortia that have developed appropriate adaptive machinery to access and - assimilate hydrocarbons. Biodegradation and bioemulsification are among the key processes by which marine microbes strongly affect the transport and fate of crude oil in the sea. Unraveling of the coupled physical and biochemical interactions between - microbes and oil droplets will be a major enabler for achieving a new level of prediction of crude oil dispersion as well as for developing more efficient bioremediation techniques to combat oil spills in marine environments. The proposed research - project aims at an improved understanding of the fundamental microscale mechanisms that underpin oil biodegradation with a highly innovative focus at both the single-droplet and droplet-population levels. In particular, at the single-droplet level, - our focus is on the droplet-microbe interactions and the dynamics of biofilm formation over the oily substrate. Ultimately, the developing interfaces between biofilms, oil and water will be tracked and quantitatively visualized. At the - droplet-population level, our focus is on the evolution of the droplet size distribution (DSD) and its impact on the average biodegradation rates for a cloud of oil microdroplets (10-60 um). The research methodology is based on a creative combination - of state-of-the-art microfluidics, biochemical analyses and computational modeling. All in all, this project is expected to provide a unique and original approach to a fundamental problem in microbial ecology that has wide societal and economical - repercussions. Importantly, a profound impetus will be given to the Researcher’s career via strengthening his publication record and his professional network of contacts. - - 2020-01-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Greece - - - OILY MICROCOSM - - - H2020-MSCA-IF-2016 - - - 741799 - - - - - CONSIGLIO NAZIONALE DELLE RICERCHE - CONSIGLIO NAZIONALE DELLE RICERCHE - - - EUR 1 880 060 - - - Full-scale COmputational design of Porous mesoscale MATerials - - - EUR 1 880 060 - - - Italy - Italy - - - Research Organisations - Research Organisations - - The last decades have witnessed major progress in our understanding of the basic physics of soft matter materials. At the same time, microfluidics has also undergone spectacular theoretical and experimental progress. The - confluence of such major advances spawns unprecedented opportunities for the design and manufacturing of new soft mesoscale materials, with promising applications in tissue engineering, photonics, catalysis and many others. COPMAT is targeted at - making the most this opportunity through the pursuit of a single general goal: the full-scale simulation at nanometric resolution of micro-reactors for the design and synthesis of new tunable porous materials. In particular, we shall focus on the - microfluidic design of: multi-jel materials, trabecular porous media and soft mesoscale molecules. We shall also explore new designs concepts based on unexplored microscale phenomena, such as the interaction between plasticity and nano-rugosity. The - complex interplay between the highly non-linear rheology of soft materials and the major experimental control parameters leads to an engineering design of formidable complexity, characterized by a strong sensitivity of the macroscale material - properties on the details of nanoscale interfacial interactions. COPMAT will tackle this formidable multiscale challenge through the deployment of an entirely new family of multiscale techniques, centered upon highly innovative extensions of the - Lattice Boltzmann method and its combinations with Immersed Boundary Method, Dissipative Particle Dynamics and Dissipative Voronoi Dynamics. The success of COPMAT will be gauged by its capability of inspiring and realizing the design of microfluidic - devices for the synthesis of novel families of porous materials for bio-engineering applications. The new paradigm established by COPMAT for the computational design of soft materials is expected to extend well beyond the time-horizon of the project. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Italy - - - COPMAT - - - ERC-2016-ADG - - - 739964 - - - - - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - - - EUR 1 525 925 - - - Small animal proton Irradiator for Research in Molecular Image-guided radiation-Oncology - - - EUR 1 525 925 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Precision small animal radiotherapy (RT) research is a young emerging field aiming at unravelling complex in-vivo mechanisms of radiation damage in target and non-target tissues, for translation into improved clinical treatment strategies. - - 2021-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - SIRMIO - - - ERC-2016-COG - - - 725539 - - - - - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - - - EUR 1 500 000 - - - Age-dependent Regulation of Dendritic Cell Development and Function - - - EUR 1 500 000 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Early life immune balance is essential for survival and establishment of healthy immunity in later life. We aim to define how age-dependent regulation of dendritic cell (DC) development contributes to this crucial immune - balance. DCs are versatile controllers of immunity that in neonates are qualitatively distinct from adults. Why such age-dependent differences exist is unclear but newborn DCs are considered underdeveloped and functionally immature. - - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - Baby DCs - - - ERC-2016-STG - - - 715182 - - - - - MEDICAL RESEARCH COUNCIL - - - EUR 183 454,80 - - - Molecular basis for securin and cyclin ubiquitylation by the anaphase-promoting complex (APC/C) - - - EUR 183 454,80 - - - United Kingdom - - - Research Organisations - - This research proposal describes an ambitious effort to characterize structurally and biochemically ubiquitin chain initiation and elongation by the anaphase-promoting complex or cyclosome (APC/C) in complex with two - well-characterized substrates. The APC/C is a multi-subunit cullin-RING E3 ubiquitin ligase that controls progression through the cell cycle by a temporal regulation of its activity and substrate specificity. Regulation and specificity of this E3 - ligase is achieved through mutually exclusive binding of two structurally related co-activator subunits termed Cdc20 and Cdh1, as well as through APC/C inhibitors, varying substrate affinities and auto-ubiquitylation of its cognate E2s, namely UbcH10 - and Ube2S. In order to understand ubiquitin chain initiation and elongation of the two well-known APC/C substrates cyclin B and securin, I am aiming to use a combined approach of cryo-electron microscopy, X-ray crystallography and a variety of - biochemical methods. Within this project I will use cryo-electron microscopy studies to uncover the molecular mechanisms of substrate recognition and ubiquitin chain initiation and elongation by analyzing the APC/CCdh1 co-activator complex bound to - its transiently associated E2 enzymes Ube2S or UbcH10 and one of the aforementioned high affinity substrates. - - - 2018-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - APCINTERACTIONS - - - H2020-MSCA-IF-2014 - - - 657725 - - - - - INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM - JANSSEN CILAG SA - VYSOKA SKOLA BANSKA - TECHNICKA UNIVERZITA OSTRAVA - ASTRAZENECA AB - UNIVERSITAT LINZ - AALTO-KORKEAKOULUSAATIO - INTEL CORPORATION - IDEACONSULT LIMITED LIABILITY COMPANY - ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE - - - EUR 3 910 140 - - - Exascale Compound Activity Prediction Engine - - - EUR 3 910 140 - - - Belgium - Spain - Czech Republic - Sweden - Austria - Finland - Belgium - Bulgaria - United Kingdom - - - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - Scalable machine learning of complex models on extreme data will be an important industrial application of exascale computers. In this project, we take the example of predicting compound bioactivity for the pharmaceutical - industry, an important sector for Europe for employment, income, and solving the problems of an ageing society. Small scale approaches to machine learning have already been trialed and show great promise to reduce empirical testing costs by acting as - a virtual screen to filter out tests unlikely to work. However, it is not yet possible to use all available data to make the best possible models, as algorithms (and their implementations) capable of learning the best models do not scale to such - sizes and heterogeneity of input data. There are also further challenges including imbalanced data, confidence estimation, data standards model quality and feature diversity. - - 2018-08-31, ongoing project | - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.2."> - - - FETHPC-1-2014 - HPC Core Technologies, Programming Environments and Algorithms for Extreme Parallelism and Extreme Data Applications - - - RIA - Research and Innovation action - - - Belgium - - - ExCAPE - - - H2020-FETHPC-2014 - - - 671555 - - - - - UNIVERSITY COLLEGE LONDON - UNIVERSITAET DUISBURG-ESSEN - DANMARKS TEKNISKE UNIVERSITET - INSTITUT POLYTECHNIQUE DE GRENOBLE - UNIVERSIDAD CARLOS III DE MADRID - UNIVERSITY OF CYPRUS - UNIVERZA V LJUBLJANI - BUDAPESTI MUSZAKI ES GAZDASAGTUDOMANYI EGYETEM - CONSORZIO NAZIONALE INTERUNIVERSITARIO PER LE TELECOMUNICAZIONI - III-V LAB - - - EUR 3 867 896,88 - - - FIber-Wireless Integrated Networks for 5th Generation delivery. - - - EUR 3 867 896,88 - - - United Kingdom - Germany - Denmark - France - Spain - Cyprus - Slovenia - Hungary - Italy - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - This European Training Network aims to produce the next generation of early stage researchers who will enable Europe to take a leading role in the development of future devices, systems and networks supporting the 5G - high-speed wireless internet. To do this, researchers must be able to work in interdisciplinary teams, integrate their activities, share expertise, and promote a vision of a converged wireless and optical devices and networks that efficiently - supports the services and applications being demanded. A large number of technologies and devices will need to converge, co-exist and interoperate, and most importantly, cooperate, if this vision is to be efficiently and cost-effectively realised. A - key area within this next generation jigsaw is the integration of optical fibre networks and radio networks at mm-wave frequencies, to provide high-bandwidth front/backhaul services and enable scalable and manageable networks without a highly complex - interface structure and multiple overlaid protocols. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - FIWIN5G - - - H2020-MSCA-ITN-2014 - - - 642355 - - - - - ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE - - - EUR 146 591,10 - - - ‘The re-privatization of the contemporary art world: private collectors and artist-entrepreneurs in the changing geographies of European art’ - - - EUR 146 591,10 - - - United Kingdom - - - Higher or Secondary Education Establishments - - This project examines the idea that there is an on-going re-privatization of the European art world, in which increasingly it is private art collectors and communities of artist-entrepreneurs that are creating commercial value - in the contemporary art market and redrawing our cultural landscape. The rapid expansion of the global art market has meant that art has entered a period of radical institutional, market and industry transformation. Private art collectors and - artist-entrepreneurs are now competing with public institutions and the locus of power is moving from public to private actors. This change calls for new critical investigations of agency, value creation and creativity of the art world. My work - addresses an area of activity that is central to both European cultural and economic development. The thriving European art scene is a key field within the creative and cultural industries identified as central to Europe’s development and integration - by both the Creative Europe strategy and the Europe 2020 strategy. - - - 2018-06-30, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - Art market - - - H2020-MSCA-IF-2014 - - - 660629 - - - - - HEINRICH-HEINE-UNIVERSITAET DUESSELDORF - HEINRICH-HEINE-UNIVERSITAET DUESSELDORF - - - EUR 1 920 697 - - - Control of amyloid formation via beta-hairpin molecular recognition features - - - EUR 1 920 697 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The aggregation of proteins into amyloid fibrils is involved in various diseases which place a high burden on patients, families, caregivers, and healthcare systems, including Alzheimer’s disease, Parkinson’s disease and type - 2 diabetes. While the therapeutic potential of the inhibition of amyloid formation and spreading has been recognized, there is a lack of effective strategies targeting the early steps of the aggregation reaction. - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - BETACONTROL - - - ERC-2016-COG - - - 726368 - - - - - UNIVERSIDAD CARLOS III DE MADRID - UNIVERSITE DE LORRAINE - TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY - CIMULEC - AEROSERTEC SL - - - EUR 2 052 846,72 - - - The outstanding challenge in solid mechanics: engineering structures subjected to extreme loading conditions - - - EUR 2 052 846,72 - - - Spain - France - Israel - France - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - In this project we aim to train early-stage researchers in what is referred to as an outstanding challenge in solid mechanics: developing novel solutions for the analysis and design of aerospace and defense structures - subjected to extreme loading conditions. Structural elements used in these sectors are frequently subjected to a large variety of unusually severe thermo-mechanical solicitations. One easily realizes that this type of structures (e.g. components for - satellites) has to be designed to sustain extreme temperatures, which may vary hundred degrees in short periods of time, and extreme mechanical loadings like hypervelocity impacts. New specific structural solutions are constantly developed to fulfill - such requirements, which place these industrial sectors in the forefront of the technological innovation. Hereby, aerospace and defense industries constitute the natural meeting point between academia and entrepreneurial fabric. A deep understanding - of the response of structures under the aforementioned sharp solicitations is mandatory for design purposes. Unfortunately, not even today is easy to find researchers in the labour market with such specific (and complicated) understanding. Aerospace - and defence industries require highly-qualified technical staff capable of developing research and innovation within the framework of structural mechanics. This is the precise context where our proposal lies. We intend to form a consortium composed - of 3 academic beneficiaries and 2 industrial beneficiaries which aims at developing specific training for early-stage researchers within the field of aerospace and defense structures subjected to severe thermo-mechanical loads. The leitmotif of this - ITN is to train creative and innovative researchers ready to face structural-engineering challenges which arise in the vanguard of technological innovation. - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Spain - - - OUTCOME - - - H2020-MSCA-ITN-2015 - - - 675602 - - - - - ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE - - - EUR 183 454,80 - - - Moment inequalities in matrix algebras - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - In the last few years the non-commutative moment inequalities have received a considerable attention in matrix analysis and operator theory. This phenomenon originates on the one hand in studies on the extreme properties of - the standard deviation in quantum information theory, and on the other hand, in the recent concept and developments of quantum metric spaces. This research project will investigate trace inequalities in matrix algebras. Particular attention will be - paid on moment inequalities for matrices with a special emphasis on their counterparts in operator algebras. It will focus on determining the best upper and lower bounds for higher order central moments in matrix algebras. This will be followed by a - study of the relatively new concept of Leibniz seminorms in Banach algebras. The project will pursue a research on the strong Leibniz property of central moments in non-commutative probability spaces as well as in the classical ones in order to solve - the recent question whether every centered moment has the strong Leibniz property or not. - - 2017-08-31, closed project | - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - Moments - - - H2020-MSCA-IF-2014 - - - 653943 - - - - - UNIVERSIDAD CARLOS III DE MADRID - UNIVERSIDAD CARLOS III DE MADRID - - - EUR 1 516 287,50 - - - Market Design: Theory and Applications in Development - - - EUR 1 516 287,50 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - There are two components to my research plan. - - 2021-07-31, ongoing project - - - 2016-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Spain - - - Market Design - - - ERC-2015-CoG - - - 681575 - - - - - UNIVERSIDAD CARLOS III DE MADRID - UNIVERSIDAD CARLOS III DE MADRID - - - EUR 1 133 396 - - - The Transformation of Popular Politics in Europe’s Long Nineteenth Century - - - EUR 1 133 396 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - How did ordinary people acquire the capacity to mobilize and influence the political decision-making process? How did standard forms of popular collective action emerge and get institutionalized in European modernity? To - address these questions, this project explores the transformation of European popular politics in the long nineteenth-century (c. 1789-1914), while also offering a systematic and empirically rigorous causal account of the processes that led to the - emergence of the typical forms of social movement activities that dominate the current landscape of popular protest. - - - 2020-07-31, ongoing project - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Spain - - - TRANSPOP - - - ERC-2014-CoG - - - 648429 - - - - - UNIVERSITY OF KENT - UNIVERSIDAD CARLOS III DE MADRID - UNIVERSITA DEGLI STUDI ROMA TRE - POLITECHNIKA WARSZAWSKA - OTTO-VON-GUERICKE-UNIVERSITAET MAGDEBURG - - - EUR 2 505 152,16 - - - AMBER - enhAnced Mobile BiomEtRics - - - EUR 2 505 152,16 - - - United Kingdom - Spain - Italy - Poland - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Over recent years the ubiquity of mobile platforms such as smartphones and tablets devices has rapidly increased. These devices provide a range of untethered interaction unimaginable a decade previously. With this ability to - interact with services and individuals comes the need to accurately authenticate the identity of the person requesting the transaction many of which carry financial/legally-binding instruction. Biometric solutions have also seen increased prominence - over the past decade with large-scale implementations in areas such as passport and national ID systems. The adoption of specific biometric sensors by mobile vendors indicates a long-term strategy as a means of authentication. This adoption is is at - critical point – users need to be confident of biometrics in terms of usability, privacy and performance; compromise in any one of these categories will lead to mistrust and a reluctance to adopt over and above conventional forms of authentication. - The design, implementation and assessment of biometrics on mobile devices therefore requires a range of solutions to aid initial and continued adoption. The EU needs to have experts trained specifically in the field to ensure that it participates, - competes and succeeds in the global market. - - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - AMBER - - - H2020-MSCA-ITN-2015 - - - 675087 - - - - - UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN - RUHR-UNIVERSITAET BOCHUM - RIJKSUNIVERSITEIT GRONINGEN - UNIVERSIDAD DE LA IGLESIA DE DEUSTO ENTIDAD RELIGIOSA - FUTURE ANALYTICS CONSULTING LIMITED - CONCERN WORLDWIDE LBG - PLAN LIMITED - - - EUR 1 129 500 - - - Preparedness and Resilience to address Urban Vulnerability - - - EUR 1 129 500 - - - Ireland - Germany - Netherlands - Spain - Ireland - Ireland - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The challenge posed by urban vulnerability is immense and is being compounded by rapid unplanned urbanisation, climate change and resource pressures. While the realisation that there is a fundamental shift in the landscape of - crises to cities is no longer contested, aid actors are nonetheless grappling with the complexities of adapting their approaches to the urban context. The Preparedness and Resilience to address Urban Vulnerability (PRUV) Consortium aims to inform the - pressing need to reshape how humanitarian action and development aid is undertaken in urban areas to address the challenge posed by urban vulnerability. - - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Ireland - - - PRUV - - - H2020-MSCA-RISE-2015 - - - 691060 - - - - - UNIVERSIDAD POLITECNICA DE MADRID - UNIVERSIDAD POLITECNICA DE MADRID - UNIVERSIDAD CARLOS III DE MADRID - - - EUR 2 497 000 - - - Coherent Structures in Wall-bounded Turbulence - - - EUR 2 497 000 - - - Spain - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Turbulence is a multiscale phenomenon for which control efforts have often failed because the dimension of the attractor is large. However, kinetic energy and drag are controlled by relatively few slowly evolving large - structures that sit on top of a multiscale cascade of smaller eddies. They are essentially single-scale phenomena whose evolution can be described using less information than for the full flow. In evolutionary terms they are punctuated ‘equilibria’ - for which chaotic evolution is only intermittent. The rest of the time they can be considered coherent and predictable for relatively long periods. Coherent structures studied in the 1970s in free-shear flows (e.g. jets) eventually led to increased - understanding and to industrial applications. In wall-bounded cases (e.g. boundary layers), proposed structures range from exact permanent waves and orbits to qualitative observations such as hairpins or ejections. Although most of them have been - described at low Reynolds numbers, there are reasons to believe that they persist at higher ones in the ‘LES’ sense in which small scales are treated statistically. Recent computational and experimental advances provide enough temporally and - spatially resolved data to quantify the relevance of such models to fully developed flows. We propose to use mostly existing numerical data bases to test the various models of wall-bounded coherent structures, to quantify how often and how closely - the flow approaches them, and to develop moderate-time predictions. Existing solutions will be extended to the LES equations, methods will be sought to identify them in fully turbulent flows, and reduced-order models will be developed and tested. In - practical situations, the idea is to be able to detect large eddies and to predict them ‘most of the time’. If simple enough models are found, the process will be implemented in the laboratory and used to suggest control strategies. - - 2021-01-31, ongoing project - - - 2016-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Spain - - - COTURB - - - ERC-2014-ADG - - - 669505 - - - - - THE UNIVERSITY OF WARWICK - THE UNIVERSITY OF BIRMINGHAM - KARLSRUHER INSTITUT FUER TECHNOLOGIE - CARL VON OSSIETZKY UNIVERSITAET OLDENBURG - TTY-SAATIO - ASOCIACION CENTRO TECNOLOGICO CEIT-IK4 - - - EUR 841 500 - - - Design and Fabrication of Functional Surfaces with Controllable Wettability, Adhesion and Reflectivity - - - EUR 1 291 500 - - - United Kingdom - United Kingdom - Germany - Germany - Finland - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - The project “Design and Fabrication of Functional Surfaces with Controllable Wettability, Adhesion and Reflectivity (FabSurfWAR)” focuses on the staff exchange between the partners of EU and Asia, and the development of key - enabling techniques of designing and generating micro/nano surface topology with better control of bacterial growth, adhesion, friction and other tribological properties for potential applications from surgical tools, biomedical devices, to turbine - blades and agricultural machines. It meets the objectives and requirements of the Marie Skłodowska-Curie Actions: Research and Innovation Staff Exchange (RISE), by establishing multiple bridges between European and Asian institutions. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - United Kingdom - - - FabSurfWAR - - - H2020-MSCA-RISE-2014 - - - 644971 - - - - - INSTITUT NATIONAL D'ETUDES DEMOGRAPHIQUES - UNIVERSITE CATHOLIQUE DE LOUVAIN - UNIVERSITE DE GENEVE - INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT - UNIVERSITE PARIS OUEST NANTERRE LA DEFENSE - - - EUR 868 500 - - - Emerging population issues in sub-Saharan Africa: Cross-checking and promoting demographic data for better action - - - EUR 868 500 - - - France - Belgium - Switzerland - France - France - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - - DEMOSTAF (DEMOgraphy-STatistics-for-Africa) brings together European and African research institutes as well as non academic African national statistics offices (NSOs) in a staff exchange programme, for a period of 48 months, - with the aim to advance research on emerging population issues in Sub-Saharan Africa (SSA). DemoStAf is built around four major population-related themes: fertility, mortality & health, households & families and education. These themes - federate the research projects conducted by the partners, and aim to shed light on key contemporaneous questions, with the objective to inform the post-2015 development agenda framed in the Sustainable Development Goals (SDGs) currently in - discussion. The programme focuses on the articulation between quantitative data from national statistics (censuses and sample surveys) and local data (demographic surveillance systems or local vital registration). Thanks to the close involvement of - NSOs, the programme will consolidate and promote public statistics. The programme will finance staff mobility between partners for supporting research projects, while reinforcing training and skill transfers. Collective activities essentially devoted - to training, data documentation and scientific dissemination are also planned. DemoStAf involves 17 partners: 4 European academic institutions, well known for their African population expertise (INED and IRD in France, UCL in Belgium, Unige in - Switzerland), 12 African partners from Burkina Faso (INSD and ISSP), Kenya (APHRC), Madagascar (INSTAT, INSPC, IPM, UCM), Mali (INSTAT), Senegal (ANSD, UCAD, UZ) and Uganda (UM). Among them, 4 are NSOs. Due to mutual interests in the promotion of - demographic data, a Canadian academic institution (ODSEF) is also involved. A scientific advisory committee with 11 members associates key experts and promote international partnerships. In total, 94 individuals participate, 74 are involved in 166 - secondments (that correspond to 193 months). - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - France - - - DEMOSTAF - - - H2020-MSCA-RISE-2015 - - - 690984 - - - - - HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF EV - ABENGOA RESEARCH SL - CRANFIELD UNIVERSITY - METAL ESTALKI SL - NANO4ENERGY SLNE - PROFACTOR GMBH - - - EUR 346 500 - - - Framework of Innovation for Engineering of New Durable Solar Surfaces - - - EUR 346 500 - - - Germany - Spain - United Kingdom - Spain - Spain - Austria - - - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Christian Eitzinger - Tel.: +43 7282 885250 - Fax: +43 7252 885101 - - Increasing the share of renewables in the European energy mix has a key function for the security of energy supply and the reduction of greenhouse gas emissions from fossil fuels. This proposal is entitled “Framework of - Innovation for Engineering of New Durable Solar Surfaces”, (acronym FRIENDS2) and aims at achieving a European network for the transfer of knowledge to establish a shared culture of research and innovation which allows turning creative ideas in the - field of surface engineering into innovative solutions for concentrating solar power (CSP) applications. FRIENDS2 will be led by one large European industry (Abengoa) who is a world leader in the development of CSP plants. The other FRIENDS2 - participants are two well-recognized academic organizations (the University of Cranfield and the Helmholtz-Zentrum Dresden - Rossendorf e.V.), and one SME (Metal Estalki). The purpose of FRIENDS2 is to strengthen the inter-sectoral capabilities in - research and development of coating designs in order to improve the performance of CSP key components (reflectors, receivers and containers for heat storage) for high temperature applications. The methodology of this joint research proposal contains - aspects of very high novelty. It includes computer modelling, multi-technique coating deposition, use of advanced characterization techniques, and the possibility of scaling-up new coating developments. Special attention is paid to the intersectoral - transfer of knowledge and to the establishment of a long-lasting international network with global impact. It is worth noting that a substantial fraction of secondments (51%) will be carried out from the industrial to the academic sector. With the - proposed approach, there will be an effective transfer of knowledge among the partners which will pave the road from fundamental research to applied innovation of surface engineering solutions for further CSP development. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Germany - - - FRIENDS2 - - - H2020-MSCA-RISE-2014 - - - 645725 - - - - - AARHUS UNIVERSITET - - - EUR 4 956 000 - - - AIAS-COFUND II Fellowship Programme - - - EUR 9 912 000 - - - Denmark - - - Higher or Secondary Education Establishments - - The overall aim of the AIAS-COFUND II Fellowship Programme is to reinforce excellent research by establishing a large scale fellowship programme offering long term fellowships (lasting 6-36 months) in which researchers gain - freedom and independence to develop their own ideas with access to excellent facilities. The AIAS-COFUND II Fellowship Programme will enhance fellows’ genuine understanding of the methodologies and approaches of other scientific disciplines at the - highest level, and thus make cross-disciplinary inspiration and initiatives possible. The aim is also to establish a multidisciplinary training platform to strengthen researchers’ capabilities to work anywhere in Europe and attract researchers from - around the globe to Europe and thereby contributing to the European goals of increasing the numbers of researchers with innovation skills in Europe by 2020. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2016 - Co-funding of regional, national and international programmes - - - MSCA-COFUND-FP - Fellowship programmes - - - Denmark - - - AIAS-COFUND II - - - H2020-MSCA-COFUND-2016 - - - 754513 - - - - - FUNDACIO INSTITUT CATALA DE NANOCIENCIA I NANOTECNOLOGIA - - - EUR 158 121,60 - - - Complex photon-phonon coupling - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - When humans design devices to perform a given functionality, we often prioritize ordered patterns and symmetry over anything else. Optomechanics is a clear example where precisely fabricated nanometer-scale devices are - required to interface efficiently light with the mechanical vibrations of matter at the nanoscale. This coupling provides an extra degree of freedom to control the light-matter interaction. In state-of-the art optomechanical crystals, unavoidable - fabrication imperfections impose severe performance limits increasing the energy dissipation and hampering their optical and mechanical performance. - - 2018-05-31, Grant Agreement terminated - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - COPPOLa - - - H2020-MSCA-IF-2015 - - - 701590 - - - - - Institute of Science and Technology Austria - - - EUR 4 590 200 - - - ISTplus - Postdoctoral Fellowships - - - EUR 9 180 400 - - - Austria - - - Higher or Secondary Education Establishments - - ISTplus offers two-year fellowships for highly qualified, incoming postdocs fulfilling the mobility criterion, who will have the chance to join our world-class research teams in the fields of Biology, Neuroscience, - Mathematics, Physics, and Computer science at IST Austria. The fellows will be integrated in a truly interdisciplinary research environment, interacting closely with colleagues from different fields (through shared facilities, joint projects, and - events). The international dimension will be ensured by the multinational teams (with employees from more than 50 countries) and through international networking. - - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2016 - Co-funding of regional, national and international programmes - - - MSCA-COFUND-FP - Fellowship programmes - - - Austria - - - ISTplus - - - H2020-MSCA-COFUND-2016 - - - 754411 - - - - - TECHNISCHE UNIVERSITAET MUENCHEN - - - EUR 5 664 000 - - - International Network of Excellence in Science Technology - - - EUR 11 328 000 - - - Germany - - - Higher or Secondary Education Establishments - - Combining complementary research & innovation strengths with unique infrastructures across four leading European Universities of Science & Technology will provide the basis for an internationally competitive fellowship - programme. The new EuroTechPostdoc programme aims at attracting excellent experienced researchers from all over the world through an open, transparent and structured recruitment process. EuroTechPostdoc will provide exceptional research and training - opportunities for up to 80 experienced researchers funded for a 2-year period (divided in 2 calls, 10 fellowships per participant per call). The fellows will develop their skills in interdisciplinary collaboration projects between at least two - participants from two different European countries, and will be provided with the opportunity to transfer knowledge in entrepreneurship activities or by collaboration with public and industrial organisations from the combined networks of the - participants. The research programme has been carefully selected to provide the fellows with the complementary strengths, established networks and industrial collaboration in areas of high relevance to the EU’s industrial leadership: Health & - Bioengineering, Smart & Urban Mobility, Data Science & Engineering, High Performance Computing, Entrepreneurship & Innovation. The fellows will gain access to the excellent and complementary training options offered at the four - participants, and will be supported by a personal supervision and mentoring scheme, as well as excellent local support structures. The EuroTechPostdoc 3-days Workshop focuses on strengthening the fellows’ skills and network, preparation ahead of - their careers and to foster further collaborative projects between the fellows. Together with outstanding working conditions that support both family and career, the programme will thus provide the fellows with unprecedented possibilities to - diversify their career options for a leadership position within the ERA. - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2016 - Co-funding of regional, national and international programmes - - - MSCA-COFUND-FP - Fellowship programmes - - - Germany - - - EuroTechPostdoc - - - H2020-MSCA-COFUND-2016 - - - 754462 - - - - - TEAGASC - AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY - - - EUR 2 124 000 - - - Research Leaders 2025 - A Fellowship Programme developing the Next Generation of Agri-Food Research Leaders - - - EUR 4 248 000 - - - Ireland - - - Research Organisations - - The overriding objective of this programme is to foster the next generation of agri-food research leaders. Inspired by the Marie Skłodowska-Curie Actions (MSCA) Global Fellowships, it focuses on researcher-driven mobility. The - programme offers applicants the opportunity to conduct their research in an academic or non-academic organisation of their choice worldwide (outside of Ireland) for 18 months, followed by a return phase to Teagasc (Ireland) for 18 months. The - applicant will freely choose the research topic, the outgoing host (and supervisor) and the supervisor for the return phase. In addition, if the outgoing phase is with an academic host, they may choose to incorporate a secondment for up to six months - to a non-academic collaborator of their choice. Interdisciplinary projects will be encouraged and facilitated. The programme will have a total value of €5.2 million (€2.1 million from EC). It will run for 60 months and will have two funding calls; - each funding 10 fellowships (total 20 fellowships). Each fellowship will last 36 months. There will be a strong focus on the career development of the researchers, with all fellows undertaking an accredited management course, having a dedicated - career mentor (separate to their scientific supervisors) and attending an annual retreat with presentations from established research leaders in industry, academia and civil society organisations. The need to address the “leaky pipeline” whereby many - promising female researchers do not achieve senior positions is a strong focus of the programme. An International Expert Advisory Board will review all documentation for the programme to ensure that there is no unintended bias against, or - discouragement of, female applicants. Remote review cohorts and the final review panel will be gender balanced. A dedicated section of the website will highlight positive reasons for female researchers to apply for the fellowship. - - 2023-07-31, Grant Agreement signed - - - 2018-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2016 - Co-funding of regional, national and international programmes - - - MSCA-COFUND-FP - Fellowship programmes - - - Ireland - - - ResearchLeaders2025 - - - H2020-MSCA-COFUND-2016 - - - 754380 - - - - - UNIVERSITA DEGLI STUDI DI UDINE - - - EUR 180 277,20 - - - Volcano-seismic Unsupervised Labelling and ClAssificatioN Embedded in A Real-time Scenario - - - EUR 180 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - Volcanic activity has a big impact on the economy and society. Nowadays, volcano monitoring (VM) is mainly based on the analysis of the seismicity, specifically on some type of precursory events (or classes) which appear - before an eruption. The variability of the volcano-seismic classes and the increase of the seismicity in a volcano crisis difficult the manual supervised classification carried out by expert technicians to detect an event and assign it to its proper - class. Most of the VM observatories demand an automatic Volcano Seismic Recognition (VSR) to quickly detect and analyse the precursory seismicity and to correctly assess the population risk, avoiding human casualties. Nevertheless, only a few VM - facilities have their own VSR prototypes designed to monitor their volcanoes. - - 2019-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - VULCAN.ears - - - H2020-MSCA-IF-2016 - - - 749249 - - - - - INTERDISCIPLINARY CENTER (IDC) HERZLIYA - - - EUR 263 385 - - - Estimating a DSGE Model with Rare Disasters - - - EUR 263 385 - - - Israel - - - Higher or Secondary Education Establishments - - "This project will estimate a DSGE model with rare disasters using data from the Great Recession. Previous studies on rare disasters have been confined mainly to endowment economies. Extensions to production economies - (business cycle models) have been limited. In particular, DSGE models with rare disasters have not been estimated before. The main obstacle is computational, as these models are very difficult to solve. - - - 2020-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Israel - - - DSGE-RD - - - H2020-MSCA-IF-2016 - - - 746653 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 185 076 - - - Proton CT reconstruction with a Cone Beam CT prior - - - EUR 185 076 - - - France - - - Research Organisations - - "Proton therapy has become a superioralternative to conventional radiotherapy for certain clinical indications. It potentially allows to deliver high dose to the tumor while sparing healthy surrounding tissue. However, a - reduction of treatment uncertainties is required to fully exploit this advantage and precise knowledge of the relative stopping power (RSP) of the patient tissues on the day of treatment is needed to correctly predict the proton range in the - treatment planning system (TPS). Modern imaging technology plays a key role here. - - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - protonCBCT - - - H2020-MSCA-IF-2016 - - - 753370 - - - - - ACIES BIO BIOTEHNOLOSKE RAZISKAVE IN RAZVOJ DOO - - - EUR 157 287,60 - - - Metabolic Drivers of Epigenetic Modifications: metabolic inducers of histone post-translational modifications in a biological setting - - - EUR 157 287,60 - - - Slovenia - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Post-translational chemical modifications to histone proteins – the storage units of DNA – influence gene expression electrostatically and through specific protein-protein interactions, the study of which is known as - epigenetics. Although many enzymes have been identified which add, remove or recognise these modifications, the implication of metabolism in the induction of epigenetic states is a recent development – particularly highlighting acetyl coenzyme A - (CoA) as the sole donor for acetylation. Due to the lack of appropriate biochemical tools, this emerging field has not yet been exploited, however Acies Bio’s leading work on the efficient synthesis of 4’ phosphopantetheine (4-PPT), a natural - precursor of the prolific substrate CoA, places us in a unique position to realise the novel approach of metabolically inducing epigenetic modifications. In progress towards therapeutic use bypassing faulty metabolism in a rare genetic disorder, we - have shown that 4-PPT is cell permeable, serum-stable, tolerated at high doses without side-effects, and can also upregulate histone acetylation. This presents a previously unexplored route to develop 4-PPT as a novel vehicle for the delivery of - diverse intracellular acyl-CoA species, and subsequent histone modification. Taking advantage of the interplay between metabolic and epigenetic states, and the complementarity of backgrounds that Acies Bio and Dr Sekirnik can provide through an - international partnership combining expertise in both fields, our proposed work would illuminate recently characterised histone acylations. By synthesising novel 4-PPT derivatives, and demonstrating their activity on a cellular and model organism - level, we will develop new tools to enable rapid enrichment of rare endogenous modifications to probe their function. This would form the first demonstration of use of native enzyme substrates to affect epigenetic states, affording new European - research opportunities in both metabolomics and epigenetics. - - 2020-04-30, Grant Agreement signed - - - 2018-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-SE - Society and Enterprise panel - - - Slovenia - - - M-DrivE - - - H2020-MSCA-IF-2016 - - - 748139 - - - - - ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE - ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE - UNIVERSITY OF BRISTOL - QUEEN MARY UNIVERSITY OF LONDON - UNIVERSITY OF LEEDS - UNIVERSITY COLLEGE LONDON - - - EUR 1 422 010,20 - - - Honeybee communication: animal social learning at the height of social complexity - - - EUR 1 422 010,20 - - - United Kingdom - United Kingdom - United Kingdom - United Kingdom - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Learning from others is fundamental to ecological success across the animal kingdom, but a key theme to emerge from recent research is that individuals respond differently to social information. Understanding this diversity is - an imposing challenge, because it is hard to replicate the overwhelming complexity of free-living groups within controlled laboratory conditions. Yet here I propose that one of the most complex social models that we know of— the sophisticated - eusocial societies of honeybees— offer unrivaled and yet unrecognized potential to study social information flow through a natural group. The honeybee “dance language” is one of the most celebrated communication systems in the animal world, and - central to a powerful information network that drives our most high-profile pollinator to food, but bee colonies are uniquely tractable for two reasons. Firstly, next-generation transcriptomics could allow us to delve deep into this complexity at the - molecular level, on a scale that is simply not available in vertebrate social systems. I propose to track information flow through a natural group using brain gene expression profiles, to understand how dances elicit learning in the bee brain. - Secondly, although bee foraging ranges are vast and diverse, social learning takes place in one centralized location (the hive). The social sciences now offer powerful new tools to analyze social networks, and I will use a cutting-edge network-based - modelling approach to understand how the importance of social learning mechanisms shifts with ecology. In the face of global pollinator decline, understanding the contribution of foraging drivers to colony success has never been more pressing, but - the importance of the dance language reaches far beyond food security concerns. This research integrates proximate and ultimate perspectives to produce a comprehensive, multi-disciplinary program; a high-risk, high-gain journey into new territory for - understanding animal communication. - - 2021-01-31, ongoing project - - - 2016-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - BeeDanceGap - - - ERC-2014-STG - - - 638873 - - - - - UNIVERSIDAD POMPEU FABRA - - - EUR 158 121,60 - - - A Theory of Reference for Distributional Semantics - - - EUR 158 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - One of the most fundamental human faculties is 'reference': the capacity to 'talk about things'. This extraordinary ability is at the core of many forms of human exchange, from asking for the salt at the dinner table to - collaboratively building a solar probe. It involves using linguistic signs to identify things in the world and bring them to the mind of another. Reference is poorly understood: in particular, we do not know how humans build a shared linguistic - representation of their environment, which they use to link words and world. My goal is to build a computational model of the way people acquire world knowledge from language and translate knowledge back into language. My overall framework includes - three steps: 1) creating a representation of the way people 'talk about things', using distributional semantics (DS: a computational approach to modelling word usage); 2) automatically mapping the distributional model onto a partial set-theoretic - model (a formal knowledge representation expressing shared beliefs about the world); 3) using the set-theoretic model to generate unobserved linguistic expressions which refer. The pipeline will be evaluated via an online game where a computer has to - produce references to well-known concepts and individuals for a human tester. This work will significantly advance the state-of-the-art in linguistics: while DS has enjoyed considerable success in modelling lexical phenomena, it is currently showing - its limits in explaining referential aspects of meaning. Conversely, referential semantics is still far from fully explaining the cognitive aspects of concept acquisition and reuse. The proposed investigation requires a very novel integration of - computational semantics (my area of expertise) and formal linguistics (in which my host is an internationally recognised expert). The collaboration will give us the chance to lead a burgeoning area of research aiming at integrating reference into DS. - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - ThReDS - - - H2020-MSCA-IF-2016 - - - 751250 - - - - - UNIVERSITAT POLITECNICA DE VALENCIA - UNIVERSITAT POLITECNICA DE VALENCIA - - - EUR 2 494 444 - - - Universal microwave photonics programmable processor for seamlessly interfacing wireless and optical ICT systems - - - EUR 2 494 444 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Information and communication technology (ICT) systems are expanding at an awesome pace in terms of capacity demand, number of connected end-users and required infrastructure. To cope with these rapidly increasing growth rates - there is a need for a flexible, scalable and future-proof solution for seamlessly interfacing the wireless and photonic segments of communication networks. - - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Spain - - - UMWP-CHIP - - - ERC-2016-ADG - - - 741415 - - - - - FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA) - - - EUR 170 121,60 - - - Computational design of proteins binding nucleosomal DNA with specificity for therapeutic applications - - - EUR 170 121,60 - - - Spain - - - Research Organisations - - DNA compresses in the cell by forming nucleosome particles, which diminish the accessibility of transcription factors to DNA and provide fine regulatory mechanisms for gene expression and replication. Some proteins can still - bind the exposed face of nucleosomal DNA and are known to promote cancer or viral infection, and strategies to block such binding events are promising for developing new epigenetic-like therapies. However, structural information on proteins binding - nucleosomal DNA is too limited for the rational design of new drugs. The current proposal aims to combine expertise of the researcher (on protein design) and the host group (on DNA and protein-DNA interactions) to computationally design and - experimentally test proteins binding nucleosomal DNA with specificity. The researcher will first develop a computational design protocol and subsequently test it against nucleosomes of known structure. After experimental validation, he will design - proteins blocking the nucleosomal DNA sites targeted by two proteins (FoxA1 and GATA) known to promote breast and prostate cancer. The proposed project uses computational approaches for designing protein structures and protein-DNA interactions, and - experimental approaches to characterize protein-DNA binding and structure of the designed complexes. This multidisciplinary project is devised to expand the design capabilities of the researcher towards protein-DNA interactions, which hold great - potential for medical and biotechnological applications, in a research context of high biomedical impact. This project devises a training plan on computational, experimental and transferable skills necessary for an independent research position, and - provides an opportunity to bring protein design approaches into the European research. The novelty of this protein-DNA design approach will be of wide interest for the scientific and non-scientific communities, and will be disseminated accordingly. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Spain - - - DesProtDNA - - - H2020-MSCA-IF-2016 - - - 749059 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 158 121,60 - - - Collectiveware: Highly-parallel algorithms for collective intelligence - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - In recent years, more and more scenarios pose challenges that require collective intelligence solutions based on networks (knowledge networks, social networks, sensor networks). New forms of collaborative consumption, - collaborative making, collaborative production, all rely on a common task, the formation of collectives. This task is crucial in many real-world applications domains. Notable examples of actual-world collective formation scenarios are Collective - Energy Purchasing (CEP), a collaborative consumption scenario, and Team Formation (TF), a collaborative production scenario. Within the Artificial Intelligence literature, current state of the art algorithms cannot provide the level of scalability - and the solution quality required by actual-world collective formation problems, hence novel algorithms are needed to tackle these problems. To achieve this objective, we aim at proposing novel algorithms that are capable to exploit modern - highly-parallel architectures. On the one hand, highly-parallel architectures have been successfully applied in many different scenarios so to achieve tremendous performance improvements. These advancements encourage the investigation of - parallelisation also in collective formation, with the objective of achieving the same benefits. On the other hand, our past research indicates that considering the structure of the collective formation problem leads to notable benefits in terms of - scalability and solution quality. Thus, we propose to take a novel algorithmic design approach that considers both the structure of the scenario and at the same time exploits modern highly-parallel architectures. Our algorithms will be evaluated in - two prominent collective intelligence application domains: the CEP and TF domains. The choice of these two application domains will serve to show the generality of our algorithmic design approach, since they are representative of two structurally - different families of actual-world collective formation problems. - - 2019-06-15, ongoing project - - - 2017-06-16 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - HPA4CF - - - H2020-MSCA-IF-2016 - - - 751608 - - - - - UNIVERSITE DE GENEVE - - - EUR 175 419,60 - - - Intrinsically chiral gold nanoclusters as enantiodiscriminating sensors for methamphetamines. - - - EUR 175 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - "The GOLDENSENS project aims at creating a new class of enantiodiscriminating sensors for methamphetamines based on intrinsically chiral Au38(SR)24 nanoclusters. These materials have unique optical properties which make them - capable of conferring chirality to thiols protecting their surface, even when ligands themselves are achiral. The result of this chirality transfer is the formation of an asymmetric environment on the cluster surface which will be used for the - enantiodiscrimination of D- and L-methamphetamines which can have distinct biological effects (The D-enantiomer is diffuse as psychotropic drug, whereas the L-enantiomer have been applied in medicine as in nasal decongestant). The first objective of - GOLDENSENS will be the preparation of functional Au38 clusters. The protecting thiols of these novel clusters will bear specific chemical groups able to increase the enantioselective interactions with methamphetamines. The second objective will be - the investigation of chiral properties of these gold nanoclusters by a combined chiroptical techniques and theoretical calculations. Ultimately, GOLDENSENS will investigate the enantiodiscriminating activity of prepared Au38 clusters towards - methamphetamines, leading to the development of novel methods for enantiomeric separation. NMR-based techniques will quantify enantioselective interactions and "absolute configuration modulation infrared spectroscopy" will clarify the mechanism of - enantiodiscrimination by gold nanoclusters. Results and knowledge generated with GOLDENSENS will impact the understanding of chirality at the nanoscale, contributing to the growth of an emerging and frontier research field. The training provided by - the project will help the experienced researcher to refine scientific and soft skills, ultimately acquiring all the abilities and competences necessary to start an independent academic career in nanotechnology." - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - GOLDENSENS - - - H2020-MSCA-IF-2016 - - - 747209 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 301 863 - - - GeoLocLang - - - EUR 1 301 863 - - - France - France - - - Research Organisations - Research Organisations - - "I formulated recently a conjecture that should allow to geometrize the local Langlands correspondence over a non-archimedean local field. This mixes p-adic Hodge theory, the geometric Langlands program and the classical local - Langlands correspondence. This conjecture says that given a discrete local Langlands parameter of a reductive group over a local field of equal or unequal characteristic, one should be able to construct a perverse Hecke eigensheaf on the stack of - G-bundles on the "curve" I defined and studied in my joint work with Fontaine. - - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - France - - - GeoLocLang - - - ERC-2016-ADG - - - 742608 - - - - - UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6 - - - EUR 173 076 - - - A calcifying phytoplankter’s response to climate change and its role in sinking carbon in the Subarctic Ocean using spaceborne and in situ observations and ecological modelling - - - EUR 173 076 - - - France - - - Higher or Secondary Education Establishments - - Anthropogenic carbon dioxide emissions are skyrocketing, resulting in ocean warming and acidification. Yet we are only beginning to understand how this human footprint impacts phytoplankton and associated sinking carbon fluxes - to the deep ocean. WhiteShift addresses these questions for a marine calcifying phytoplankter in one of the most climate sensitive regions, the Subarctic Ocean, where the species is expanding its range northward. First, we investigate the impact of a - changing ocean on the spatiotemporal distribution of the species by a novel integrative approach connecting long-term optical satellite observations with fundamental ecological theory. Next, we examine if the enormous amounts of calcite produced by - this species ballast organic carbon using optical technology on autonomous profiling floats. WhiteShift’s generic methodology and integrative framework is directly transportable to the global ocean and will provide important new insights into the - ocean-climate nexus. - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - WhiteShift - - - H2020-MSCA-IF-2016 - - - 749949 - - - - - UNIVERSIDAD CARLOS III DE MADRID - UNIVERSIDAD CARLOS III DE MADRID - - - EUR 1 325 158 - - - Frontiers in Phononics: Parity-Time Symmetric Phononic Metamaterials - - - EUR 1 325 158 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The boost experienced by acoustic and elastic (phononic) metamaterial research during the past years has been driven by the ability to sculpture the flow of sound waves at will. Thanks to recent developments at the frontiers - of phononic metamaterials it can be identified that active phononic control is at the cutting edge of the current research on phononic metamaterials. Introducing piezoelectric semiconductors as a material platform to discover new avenues in wave - physics will have the potential to open horizons of opportunities in science of acoustic wave control. Electrically biased piezoelectric semiconductors are non-reciprocal by nature, produce mechanical gain and are highly tunable. - - - 2021-11-30, ongoing project - - - 2016-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Spain - - - PHONOMETA - - - ERC-2016-STG - - - 714577 - - - - - STICHTING KATHOLIEKE UNIVERSITEIT - - - EUR 177 598,80 - - - Landscape of epigenetic control in early and late germ line development - - - EUR 177 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Germ cells have unique role in development. They are the only cells required for the transmission of genetic material from generation to generation in sexually reproducing organisms. This makes them pivotal for the survival of - species and ultimately for the propagation of life. Although germ cells undergo extensive cellular differentiation during gametogenesis, they are protected from somatic reprogramming. This requires precise control of transcriptional programs, - misregulation of which leads to infertility and developmental defects. Moreover, germ cell-like properties acquired ectopically promote tumor formation. My aim is to understand how germ cell identity is controlled in vertebrates, using zebrafish as a - genetic model. My hypothesis is that epigenetic control of gene expression is regulated in both the nucleus and cytoplasm of germ cells. In the nucleus, Polycomb Group (PcG) proteins regulate transcription by establishing repressive chromatin - modifications. In the germ cytoplasm, translational regulation by Argonaute proteins, involved in RNA silencing pathways, is pivotal for maintaining germ cell identity. However, the events that facilitate cross-talk between the nucleus and germ - cytoplasm are not known. Here, I propose to combine high-end developmental biology techniques with state-of-the art genomic technologies to investigate the cooperation between the PcG complex and Argonaute proteins during germ line development. I - believe that the crossing point between my scientific interest (events outside the nucleus) and the expertise of my supervisor (regulation in the nucleus), creates a very solid background for this proposal. It will further develop my - interdisciplinary skills and enhance my creative potential by allowing me to look at the regulation of germ cell identity from different angles. I am confident, that this proposal is the perfect stepping stone in becoming an independent scientist and - an expert in the field of epigenetic gene regulation. - - 2018-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - epiGERMetics - - - H2020-MSCA-IF-2015 - - - 705939 - - - - - UNIVERSIDAD CARLOS III DE MADRID - UNIVERSIDAD CARLOS III DE MADRID - - - EUR 1 424 000 - - - Information Theory for Low-Latency Wireless Communications - - - EUR 1 424 000 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The majority of wireless connections in the fifth generation (5G) of wireless systems will most likely be originated by autonomous machines and devices rather than by the human-operated mobile terminals for which traditional - broadband services are intended. It is thus expected that enhanced mobile-broadband services will be complemented by new services centered on machine-type communications (MTC). An important emerging area among MTC systems is that of low-latency - communications, which targets systems that require reliable real-time communication with stringent requirements on latency and reliability. - - 2022-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Spain - - - LOLITA - - - ERC-2016-STG - - - 714161 - - - - - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - - - EUR 3 540 000 - - - The LMU Research Fellowship Program: Promoting excellent early-stage postdoctoral researchers at LMU Munich - - - EUR 7 080 000 - - - Germany - - - Higher or Secondary Education Establishments - - As a leading European research university, Ludwig-Maximilians-Universitaet (LMU) Muenchen is committed to providing optimal conditions and reliable career paths for early-career researchers. To this end, the University aims to - expand its successful LMU Research Fellowship Program, which provides excellent research options and professional training conditions for outstanding international postdoctoral researchers from any field of research. The program gives Research - Fellows the opportunity to carry out their own independent research project with the support of an LMU professor. As part of COFUND, the program will be differentiated into an incoming and a new outgoing fellowship scheme and provide additional - international and cross-sectoral training opportunities to foster the mobility of Research Fellows. Incoming fellows will be able to undertake secondments of three to six months to international academic partner institutions. Alternatively, they may - collaborate with a non-academic partner institution in the Greater Munich area or elsewhere. Outgoing fellowships will be offered to excellent postdocs with a doctorate from LMU in order to promote the scientific exchange with non-EU countries. - Fellows will be seconded to an academic partner institution in a Third Country during an outgoing phase of 12 months and will be reintegrated into a department at LMU during their 12-month return phase. As a rule, incoming and outgoing fellowships - will be awarded for two years. In exceptional cases, funding for an additional year may be granted for projects whose scope and originality require additional research time as part of 2+1 fellowships. In summary, the expansion of the LMU Research - Fellowships will enhance the career development of international postdocs, extend LMU’s regional and international network of collaborations and contribute to the circulation of outstanding researchers and scientific innovations as part of the - realisation of the European Research Area. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2016 - Co-funding of regional, national and international programmes - - - MSCA-COFUND-FP - Fellowship programmes - - - Germany - - - LMUResearchFellows - - - H2020-MSCA-COFUND-2016 - - - 754388 - - - - - UNIVERSITAT WIEN - UNIVERSITAT WIEN - - - EUR 2 495 190,99 - - - The Normative and Moral Foundations of Group Agency - - - EUR 2 495 190,99 - - - Austria - Austria - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Though philosophers have debated intensely the issue of group agency in the last years, little scholarly work has yet been done on the normative constitution of group agents. The present project will fill this lacuna in a - groundbreaking way. A philosophical analysis of the constitutive conditions of individual and collective agency will be combined with recent research in moral philosophy, legal theory and economic theory on the organisational structure of - institutional agency. The first aim of the project is to provide a detailed philosophical investigation of the normative foundations of group agency and to work out the rational and moral norms that constitute and guide group agents. The second aim - is to explore the implications of such an analysis for moral and legal philosophy. The third aim of the project is to apply the philosophical results to a normative analysis of corporate and economic agents. - - 2022-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Austria - - - Group Agency - - - ERC-2016-ADG - - - 740922 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 183 454,80 - - - MYcenaean SOcial BIOarchaeology: Deciphering the interplay of funerary treatment and social dynamics in the Mycenaean period - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - MYSOBIO investigates the complex relationship between funerary treatment and wider social dynamics through a novel interpretive model based on the contextual analysis of human skeletal remains and associated mortuary data. The - research focusses on the post-mortem treatment of the body in collective mortuary assemblages. The main aim is to reconstruct, to a new level of detail, development in Mycenaean mortuary practice in the Late Bronze Age Aegean (1700-1050 BC). MYSOBIO - will unravel the diversity of social responses at death and their mutual relationship with wider socio-political developments, instrumental in the rise and fall of the Mycenaean palaces, one of the first complex societies in Europe. To achieve this, - it employs, for the first time, a holistic bioarchaeological approach that integrates up-to-date theoretical reflection in mortuary archaeology with cutting-edge, interdisciplinary scientific advances in the study of collective skeletal assemblages. - This methodology brings together traditional archaeology, current mortuary theory, biological anthropology, funerary taphonomy, forensic sciences and archaeo-thanatology, further enhanced by state-of-the-art technological innovations from other - scientific fields (social geography, applied mathematics, geomatics and archaeogenetics). The Fellowship will offer to the Experienced Researcher (ER) the opportunity to receive advanced training in these fields and achieve the research objectives, - creating a new methodological pathway to the social dimensions of prehistoric mortuary assemblages with world-wide implications for Social Bioarchaeology. At the same time, the ER will attain professional maturity and greatly advance her career - perspectives. She will acquire significant transferable skills, establish lasting multidisciplinary research networks, motivate the youth and educate the public on the social significance of archaeological research and the benefits of science. - - 2020-01-14, ongoing project - - - 2018-01-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - MYSOBIO - - - H2020-MSCA-IF-2016 - - - 747458 - - - - - FORSCHUNGSVERBUND BERLIN EV - UNI RESEARCH AS - UNIVERSITETET I BERGEN - KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW - AREFSENS ELECTRONICS BIOTECHNOLOGY INC - BLUE LOBSTER IT LIMITED - HELLENIC CENTRE FOR MARINE RESEARCH - MIDDLE EAST TECHNICAL UNIVERSITY - HELMHOLTZ ZENTRUM FUR OZEANFORSCHUNG KIEL - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UMEA UNIVERSITET - WasserCluster Lunz - Biologische Station GmbH - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - ECOLE NORMALE SUPERIEURE - AARHUS UNIVERSITET - SUOMEN YMPARISTOKESKUS - HELSINGIN YLIOPISTO - UNIVERSIDADE DE EVORA - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - NORSK INSTITUTT FOR VANNFORSKNING - UMWELTBUNDESAMT - - - EUR 9 999 804,75 - - - Network of Leading European AQUAtic MesoCOSM Facilities Connecting Mountains to Oceans from the Arctic to the Mediterranean - - - EUR 9 999 806,57 - - - Germany - Norway - Norway - Netherlands - Turkey - United Kingdom - Greece - Turkey - Germany - France - Sweden - Austria - Germany - France - Denmark - Finland - Finland - Portugal - United Kingdom - Norway - Germany - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - - Experimentation in mesocosms is arguably the single most powerful approach to obtain a mechanistic quantitative understanding of ecosystem-level impacts of stressors in complex systems, especially when embedded in long-term - observations, theoretical models and experiments conducted at other scales. AQUACOSM builds on an established European network of mesocosm research infrastructures (RI), the FP7 Infra project MESOAQUA (2009-2012), where 167 users successfully - conducted 74 projects. AQUACOSM greatly enhances that network on pelagic marine systems in at least 3 ways: first by expanding it to 10 freshwater (rivers and lakes), 2 brackish and 2 benthic marine facilities, and by involving 2 SMEs and reaching - out to more, thereby granting effective transnational access to world-leading mesocosm facilities to >340 users on >11500 days; second, by integrating scattered know-how between freshwater and marine RI; and third, by uniting aquatic mesocosm - science in an open network beyond the core consortium, with industry involved in an ambitious innovation process, to promote ground-breaking developments in mesocosm technology, instrumentation and data processing. A new dimension of experimental - ecosystem science will be reached by coordinated mesocosm experiments along transects from the Mediterranean to the Arctic and beyond salinity boundaries. These efforts will culminate in a joint research activity (JRA) to assess aquatic ecosystem - responses across multiple environmental gradients to a selected climate-related key stressor with repercussions for ecosystem services. Overall, AQUACOSM will fill a global void by forging an integrated freshwater and marine research infrastructure - network. Long-term sustainability is sought through assessing governance models based on science priorities and economic innovation opportunities. Linkages to and synergies with ESFRI RI and other large initiatives are ensured by AQUACOSM partners - and Advisory Board members in those programs. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.2."> - - - INFRAIA-01-2016-2017 - Integrating Activities for Advanced Communities - - - RIA - Research and Innovation action - - - Germany - - - AQUACOSM - - - H2020-INFRAIA-2016-1 - - - 731065 - - - - - THE BARCELONA INSTITUTE OF SCIENCE AND TECHNOLOGY - - - EUR 2 929 920 - - - COFUND BIST PREDOCTORAL PROGRAMME - - - EUR 5 859 840 - - - Spain - - - Other - - The PREBIST proposal is presented by the Barcelona Institute of Science and Technology (BIST) as beneficiary. PREBIST is an ambitious programme of 28 four-year fellowships for multidisciplinary pre-doctoral research at BIST´s - constituent research centres and associated partner institutions (hospitals, private companies, technology centres, and other academic institutions), who will provide secondments, training, networking activities and other actions to complement the - research activities and professional development of the fellows. - - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2016 - Co-funding of regional, national and international programmes - - - MSCA-COFUND-DP - Doctoral programmes - - - Spain - - - PREBIST - - - H2020-MSCA-COFUND-2016 - - - 754558 - - - - - LUNDS UNIVERSITET - LUNDS UNIVERSITET - - - EUR 1 750 000 - - - Drivers and impacts of invertebrate herbivores across forest ecosystems globally. - - - EUR 1 750 000 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Forests slow global climate change by absorbing atmospheric carbon dioxide but this ecosystem service is limited by soil nutrients. Herbivores potentially alter soil nutrients in a range of ways, but these have mostly only - been recorded for large mammals. By comparison, the impacts of the abundant invertebrates in forests have largely been ignored and are not included in current models used to generate the climate predictions so vital for designing governmental - policies - - 2021-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Sweden - - - ECOHERB - - - ERC-2015-CoG - - - 682707 - - - - - SWANSEA UNIVERSITY - - - EUR 195 454,80 - - - When the smoke clears: predicting and preventing catastrophic erosion and flooding after wildfires in volcanic terrains - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Wildfires remove protective vegetation, leaving the landscapes vulnerable to catastrophic erosion, landslides and floods. The resulting losses and mitigation costs following wildfires have increased dramatically in the last 30 - years due to (i) the population increase, (ii) the rise in fire severity and torrential rains associated with climatic change, and (iii) critical gaps in and limited transfer of knowledge on fire-effects to support decision making. Major advances - have been made in the last decade including the development of cost-risk erosion prediction tools, innovative hillslope stabilization treatments and novel approaches to monitor soil redistribution. In Europe, however, their application in post-fire - prevention plans is still in its infancy as the necessary soil-specific calibration and effectiveness testing is missing for most terrain types. - - - 2017-12-10, closed project - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - FireAndRiskPrevention - - - H2020-MSCA-IF-2014 - - - 655993 - - - - - THE BARCELONA INSTITUTE OF SCIENCE AND TECHNOLOGY - - - EUR 6 478 200 - - - COFUND BIST POSTDOCTORAL FELLOWSHIP PROGRAMME - - - EUR 12 956 400 - - - Spain - - - Other - - PROBIST is an ambitious programme offering 61 three-year fellowships to foster excellence in multidisciplinary postdoctoral research at BIST´s constituent research centres and associated partner institutions (hospitals, - private companies, technology centres, and other academic institutions), which will provide opportunities for collaborations and secondments, training, networking activities and other actions to complement the research activities and professional - development of the fellows. The PROBIST proposal is presented by the Barcelona Institute of Science and Technology (BIST) as beneficiary. - - 2022-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2016 - Co-funding of regional, national and international programmes - - - MSCA-COFUND-FP - Fellowship programmes - - - Spain - - - PROBIST - - - H2020-MSCA-COFUND-2016 - - - 754510 - - - - - FONDATION SCIENCES MATHEMATIQUES DE PARIS - - - EUR 3 139 200 - - - International Doctoral Training in Mathematical Sciences in Paris - - - EUR 6 278 400 - - - France - - - Research Organisations - - COFUND MathInParis programme will create and build upon existing networks to attract exceptional Doctoral students coming from abroad, to ensure a very high standard of Doctoral training and to disseminate good practice in - terms of selection and mentoring throughout all its Doctoral schools by means of those implemented within this programme. The programme is expected to significantly improve follow-up and mentoring conditions through the presence of dedicated - personnel and to develop the scope and modes of provision in Doctoral education. COFUND MathInParis will enhance opening of training in mathematics towards industry and other disciplines, develop new targeted mechanisms for transition of doctoral - students to businesses during their training and promote public-private mobility. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2016 - Co-funding of regional, national and international programmes - - - MSCA-COFUND-DP - Doctoral programmes - - - France - - - MathInParis - - - H2020-MSCA-COFUND-2016 - - - 754362 - - - - - ABERYSTWYTH UNIVERSITY - - - EUR 195 454,80 - - - A functional analytic approach for the analysis of nonlinear transmission problems - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The purpose of the research plan is the development of the method called Functional Analytical Approach (FAA) for the analysis of singular perturbations of nonlinear transmission problems. The techniques proposed are based on - potential theory and functional analysis and aim at describing the effect of perturbations in terms of real analytic functions. Both perturbations of the shapes of the domains of definition and of the coefficients of the operators will be considered. - A special attention will be paid to the case of perforated and periodically perforated domains with shrinking holes and inclusions. The problems addressed are of interest also in view of inter-sectorial applications to the analysis of physical models - in fluid dynamic, in elasticity, and in thermodynamic. Concrete applications will be shown in the study effective properties of composite materials, in inverse problems in acoustic and electromagnetic scattering, and in inclusion detection problems. - The results obtained represent a novelty with respect to the existing literature for the following reasons: - - 2017-11-30, Grant Agreement terminated | - - - 2015-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - FAANon - - - H2020-MSCA-IF-2014 - - - 654795 - - - - - ISTANBUL MEDIPOL UNIVERSITESI VAFKI - ISTANBUL SEHIR UNIVERSITESI - - - EUR 157 845,60 - - - Characterization and Measurement of Wideband Directional Channels in FM Band For New Efficient Wireless Systems - - - EUR 157 845,60 - - - Turkey - Turkey - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Motivation: Wireless access is being used extensively in our life. Wireless access enabler, the frequency bands, on the other hand, is very scarce. It is very important that any wireless access system utilizes the frequency at - outmost efficiency. One of the poorly utilized wireless bands is the FM Band between 88–108 MHz. The band is being allocated only for relatively high quality audio broadcast around the world. This band has good propagation characteristics and - therefore its coverage range and its penetration through buildings are excellent. As FM coverage is so ubiquitous around the world, several applications are already considered to better exploit this useful band: (a) Software defined radios for public - safety, (b) New digital audio broadcast services, and (c) the development of an emergency message delivery services. With one of these applications and good propagation characteristics, FM Band can enable a fully connected Europe. - - - 2018-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Turkey - - - FM-4NXTG - - - H2020-MSCA-IF-2015 - - - 706929 - - - - - UNIVERSITAETSKLINIKUM HAMBURG-EPPENDORF - - - EUR 171 460,80 - - - Investigating Ror2-dependent non-canonical Wnt signaling in bone remodeling - - - EUR 171 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - Wnt signaling is composed of the canonical and non-canonical pathways. Canonical Wnt signaling is dependent on β-catenin activation and has become a major focus for targeting osteoblast-mediated bone formation in the context - of treating the debilitating disease osteoporosis. However, much less is known about the role of the non-canonical pathway in bone formation. Unpublished data of the host laboratory demonstrates that targeted deletion of the non-canonical Wnt - signaling Receptor tyrosine kinase-like orphan receptor 2 (Ror2) in osteoblasts in mice causes a high bone turnover with increased bone formation and enhanced osteoclast-mediated bone resorption. I thus hypothesize that Ror2 regulates bone remodeling - by altering signaling in osteoblasts and their interaction with osteoclasts. In Aim I, I will determine cell autonomous effects of Ror2 on osteoblasts by analyzing cell differentiation, proliferation, survival, and by performing functional studies - both in vitro and in vivo. Additionally, since osteoblasts provide pro- and anti-differentiation signals to osteoclasts, Aim I will further explore if Ror2 alters the activity of these signals and investigate the resulting phenotypic changes in - osteoclast function. In Aim II, I will undertake an in-depth experimental approach combined with an innovative bioinformatics analysis to investigate the osteoblast-specific non-canonical Wnt signaling cascade downstream of Ror2 after reconstituting - Ror2-deficient cells with wild type or Ror2 mutants. Lastly, in Aim III I will directly address the therapeutic potential of Ror2 in several in vivo bone turnover models utilizing a chimeric Ror2-Fc soluble receptor. In summary, I will use state of - the art in vivo and in vitro approaches to delineate the downstream Ror2 signaling cascade in osteoblasts and its functional effect on bone remodeling. This fellowship is instrumental in catalyzing career opportunities for me as it provides an ideal - environment to reach my full potential. - - 2018-11-02, Grant Agreement terminated - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - ROR2BONE - - - H2020-MSCA-IF-2014 - - - 658632 - - - - - LEIBNIZ-INSTITUT FUR POLYMERFORSCHUNG DRESDEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - WAGENINGEN UNIVERSITY - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - LEIBNIZ-INSTITUT FUER NEUE MATERIALIEN GEMEINNUETZIGE GMBH - BASF SE - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - TECHNISCHE UNIVERSITEIT EINDHOVEN - PANEPISTIMIO PATRON - Akzo Nobel Decorative Coatings bv - IMPERIAL CHEMICAL INDUSTRIES LIMITED - - - EUR 2 822 328,36 - - - Training in Bio-Inspired Design of Smart Adhesive Materials - - - EUR 2 822 328,36 - - - Germany - Germany - Netherlands - France - Germany - Germany - United Kingdom - Netherlands - Greece - Netherlands - United Kingdom - - - Research Organisations - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The last half century has seen a tremendous advancement in adhesives technology and has led to widespread replacement of mechanical fasteners with adhesive bonds (e.g. aircraft, automobile, construction, etc.). Bonding to wet, - rough and fouled surfaces, however, remains challenging and adhesive technology is rarely applied for bonding in wet conditions, such as in (orthopaedic) medicine. Therefore, a need exists to educate young researchers in this interdisciplinary - research field of controlling adhesion under wet conditions and to bridge the gap between the fundamentals of underwater adhesives and their practice. BioSmartTrainee is set up to provide such training by a combination of three complementary - scientific fields: polymer science, adhesion and (fluid)-biomechanics. We aim to (i) extract principles from biological systems and mimic them to design synthetic materials; to (ii) experimentally test their adhesion properties in wet conditions and - to (iii) clarify the adhesion mechanisms based on natural examples and theoretical modelling. These innovative adhesives will be useful for reversible attachment to a variety of surfaces in wet environments and, therefore, be highly relevant for - products from European industry such as technological adhesives, coatings, tissue adhesives, wound dressings or transdermal delivery devices. This carefully planned research and training program in a network of leading academic and industrial (BASF, - AkzoNobel, UGRO) partners will ensure that young researchers are given an excellent training in a pioneering research domain of high scientific and technological relevance, where Europe can take a leading position. - - 2019-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - BioSmartTrainee - - - H2020-MSCA-ITN-2014 - - - 642861 - - - - - UNIWERSYTET MIKOLAJA KOPERNIKA W TORUNIU - - - EUR 146 462,40 - - - Breaking the curse of dimension in heavy-element chemistry - - - EUR 146 462,40 - - - Poland - - - Higher or Secondary Education Establishments - - The acute toxicity and radioactivity of actinide compounds complicate experimental studies of the “soup” of nuclear waste produced in nuclear reactors. This motivates research into computational approaches for determining - molecular properties and reactivity of actinide compounds. Unfortunately, the computational resources required by standard quantum chemistry methods grow exponentially with system size, an effect known as the curse of dimension. Since the - actinide-containing molecules of relevance to nuclear chemistry contain hundreds of electrons, innovative new approaches that break the curse of dimension must be developed. One such approach models many-electron molecules as collections of - noninteracting electron pairs, called geminals. Standard geminal methods are inappropriate for actinide chemistry, however, and must be extended to include (i) computationally efficient ways to account for relativistic effects, (ii) correlations - between electrons beyond electron-pairing effects (weak correlation), (iii) electronically excited states, and (iv) the description of unpaired electrons. Specifically, weak correlation will be captured using Coupled Cluster-type approaches, excited - states are accessible through an Equation-of-Motion formalism, and open-shell extensions will use generalized quasi-particles as building blocks for the electronic wavefunction. The extended geminal models thus developed will provide the first - direct, atomistic, and quantitative computational model for understanding nuclear waste reprocessing and will provide the essential insights that are needed to guide the synthesis of new actinide compounds that can be used to separate actinides from - the other components in the “soup” of nuclear waste. The developed models will be robust, computationally cheap, and black-box-like and can be used in many other areas of chemistry and materials physics like lanthanide and transition-metal chemistry, - biochemistry, and semiconductor physics. - - 2018-06-30, ongoing project - - - 2016-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Poland - - - PCCDX - - - H2020-MSCA-IF-2015 - - - 702635 - - - - - CONSORCI INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER - - - EUR 158 121,60 - - - A new therapeutic platform based on nanotechnology to promote T- and B-regulatory networks - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - The complexity of autoimmune responses is a barrier to the design of strategies that can selectively purge the immune system of autoreactivity without impairing systemic immunity. Recently, Santamaria et al. have shown that - nanoparticles (NPs) coated with type 1 diabetes (T1D)-relevant peptide–MHC (pMHC) complexes can restore normoglycemia in diabetic animals by blunting the diabetogenic autoimmune response without impairing systemic immunity. pMHC class II-NP therapy - functions by expanding, in an epitope-specific manner, autoantigen-experienced T-regulatory-1 (TR1) CD4+ T-cells that inhibit the recruitment of other autoantigenic specificities by: (1) suppressing autoantigen-loaded antigen-presenting cells in the - pancreatic lymph nodes (PLNs); and (2) promoting the differentiation of B-cells into B-regulatory cells. Importantly, they have shown that human T1D-relevant pMHC class II-NPs also promote human TR1 CD4+ T-cell formation in NSG mice engrafted with - peripheral blood mononuclear cells from recent onset T1D patients. - - - 2018-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Spain - - - NANOBreg - - - H2020-MSCA-IF-2015 - - - 704522 - - - - - UNIVERSITA DEGLI STUDI DI PADOVA - UNIVERSITA DEGLI STUDI DI PADOVA - UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II. - - - EUR 900 000 - - - Stable and Chaotic Motions in the Planetary Problem - - - EUR 900 000 - - - Italy - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The planetary problem consists in determining the motions of n planets, interacting among themselves and with a sun, via gravity only. Its deep comprehension has relevant consequences in Mathematics, Physics, Astronomy and Astrophysics. - - - 2021-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Italy - - - StableChaoticPlanetM - - - ERC-2015-STG - - - 677793 - - - - - ACADEMISCH ZIEKENHUIS GRONINGEN - ACADEMISCH ZIEKENHUIS GRONINGEN - BAYERISCHE JULIUS-MAXIMILIANS UNIVERSITAT WURZBURG - - - EUR 1 531 625 - - - G-quadruplex DNA Structures and Genome Stability - - - EUR 1 531 625 - - - Netherlands - Netherlands - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Secondary structures such as G-quadruplexes (G4s) can form within DNA or RNA. They pose a dramatic risk for genome stability, because due to their stability they can block DNA replication and this could lead to DNA breaks. In - certain cancer cells mutations/deletions are observed at G4s, if a helicase that is important for G4 unwinding is mutated. Nevertheless, G4s are also discussed to be functional elements for cellular processes such as telomere protection, - transcription, replication, and meiosis. The aim of this research proposal is to use various biochemical and computational tools to determine which proteins are essential for formation and regulation of G4s. Proposed experiments will gain insights - into both “effects” of G4s, the risk for genome stability and its significant function for the cell. In aim 1 we will elucidate and identify novel proteins that bind, regulate, and repair G4s, especially in the absence of helicases, in vitro and in - vivo. Our focus is to understand how G4s become mutated in the absence of helicases, which proteins are involved, and how genome stability is preserved. In aim 2, we will use cutting edge techniques to identify regions that form G4s in vivo. Although - there is experimental proof for G4s in vivo, this is not commonly accepted, yet. We will provide solid data that will support the existence of G4s in vivo. Furthermore, we will survey genome-wide when and why G4s become a risk for genome stability. - Aim 3 will focus on the in silico observation that G4 structures are connected to meiosis. In this aim we will use a combination of techniques to unravel the biological significance of G4s during meiosis in vivo. - - 2021-02-28, ongoing project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - G4DSB - - - ERC-2014-STG - - - 638988 - - - - - UNIVERSITE D'AIX MARSEILLE - - - EUR 185 076 - - - Speciation, sources, and fate of atmospheric organic phosphorus over the Mediterranean Sea: A missing piece of the P cycle? - - - EUR 185 076 - - - France - - - Higher or Secondary Education Establishments - - Phosphorus is a critical nutrient affecting primary productivity in large areas in oceanic ecosystems. The principal source of externally supplied nutrients in many marine ecosystems is the atmospheric deposition. As the ocean - is an important sink of atmospheric CO2, phosphorus through productivity limitation can indirectly affect global warming by removing more CO2 from the atmosphere. The importance of organic P as a potential pool of bioavailable P in the atmosphere is - not widely recognized. It is important to note that the only available data in the literature are the atmospheric measurements of phosphate and total phosphorus, while there are almost no data about the organic P, especially over Mediterranean Sea - (MS). The main goal of PHOSPHOTRAC is to shed light on the atmospheric organic P chemical identification and to test the hypothesis that the increased acidification of the atmosphere may significantly impact the bioavailability of organic P. - PHOSPHOTRAC proposes new methodologies and modern instrumentation for the identification of organic P compounds in the atmosphere. Most of them are implemented for the first time in atmospheric samples, and they will provide new insights into a - nutrient cycle of P in MS. Organic P-rich compounds of interest are DNA, RNA, ATP, phytic acid, phospholipids, degradation products of chemical weapons, organophosphate ester flame retardants and organophosphorous pesticides. Further identification - of atmospheric organic P sources in the region will be performed by using the chemical analysis data of specific tracers (ergosterol, anhydrosugars, trace metals), with statistical analysis, and implementation of atmospheric transport model TM4-ECPL - coupled with the thermodynamic model ISORROPIA-II. The proposed project is highly interdisciplinary as it combines analytical chemistry, biology, and atmospheric modeling in order to address a question of extreme ecological importance related to - climate change in the MS. - - 2018-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - PHOSPHOTRAC - - - H2020-MSCA-IF-2015 - - - 707624 - - - - - UNIVERSITY COLLEGE LONDON - UNIVERSITY COLLEGE LONDON - - - EUR 1 499 055 - - - How retrotransposons remodel the genome during early development and reprogramming - - - EUR 1 499 055 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Retrotransposons (RTNs) are ancient viruses that have stably integrated themselves into mammalian genomes and they now occupy around half of the human or mouse genome. These mobile genetic elements that have coevolved with us - drive evolution by creating new genes and plasticity of genomes. Exciting data including ours has shown that even RTNs that are no longer active retain enhancer, promoter or repressor sequences that regulate developmental genes, through largely - uncharacterized transcription factors. We have employed CRISPR/Cas9 gene disruption to determine that Zfp37 and Zfp819 bind to and regulate RTNs in mouse embryonic stem cells (ESCs). Identification of these zinc finger proteins (ZFPs) now allows us - to ask new questions about how RTNs have been co-opted to orchestrate gene circuits in vitro and in vivo. Both these factors have already been implicated to play a role in reprogramming or genome integrity. - - - 2021-12-31, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - TransposonsReprogram - - - ERC-2015-STG - - - 678350 - - - - - STOCKHOLMS UNIVERSITET - STOCKHOLMS UNIVERSITET - - - EUR 2 486 951 - - - Probing the Structure and Dynamics of Water in its Various States - - - EUR 2 486 951,25 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - We propose to address some of the most important outstanding questions for a microscopic understanding of water: What is the structure and dynamics of the hydrogen-bonding network that give rise to all the unique properties of - water? How is the structure and dynamics affected by temperature, pressure and by perturbation through interaction with solutes and interfaces? Here we point to the opportunity to exploit the completely new avenues that the novel x-ray free-electron - lasers open up for probing both structure and dynamics of water from hot temperatures down to the deeply supercooled regime where the anomalous properties become extreme. We plan to further develop fast cooling and ultrafast x-ray probing allowing - access to below the homogeneous ice nucleation limit, to probe equilibrium dynamics through probe-probe techniques based on x-ray correlation spectroscopy, to access low-energy vibrational mode dynamics through THz pump and x-ray scattering probe and - to transfer x-ray spectroscopies into the time domain. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Sweden - - - WATER - - - ERC-2014-ADG - - - 667205 - - - - - Eidgenössische Technische Hochschule Zürich - - - EUR 175 419,60 - - - Dynamic Integrated structural and proteomic Analysis of the LUBAC complex and its involvement in NF-κB and inflammation - - - EUR 175 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - One of key challenges in current biology is to characterize the genotype to phenotype transition and explain how genomic variation results in specific phenotypes. According to the 'modular biology' paradigm, dynamically - regulated multi-protein modules mediate this transition. My project aims at testing this paradigm by applying to a clinically highly relevant case study an integrated workflow of new technologies developed in the host laboratory. In particular, I - will focus on a novel ubiquitin ligase complex, linear ubiquitin chain assembly complex (LUBAC), a critical but poorly understood player in several inflammation-related pathways, most notably the canonical NF-κB pathway. Given its key role in the - pathogenesis of inflammation, understanding LUBAC will have fundamental biomedical implications. To investigate its structure, function and regulation, I will integrate data generated by mass spectrometry, which is the focus of the Aebersold - laboratory, and cryo-electron microscopy (cryo-EM), which is the main expertise I acquired during my PhD. First, I will use quantitative affinity-purification coupled to mass spectrometry (AP-SWATH) to identify the dynamic interactome and the - post-translation modifications (PTMs) of LUBAC. I will then define the structure of the complex by combining available atomic models of known LUBAC components, cryo-EM and cross-linking coupled to mass spectrometry (XL-MS). Finally, I will study - clinical mutants and map the repercussions of genetic variation at the level of the complex organization, its interactome and of the global proteomic landscape. By these means, I will give a systemic and mechanistic account of the genotype to - phenotype transition in clinically relevant scenarios. The output of the project, in line with the Work Programme, will be the production of new knowledge of fundamental biological and medical relevance and the development and validation of enabling - technologies at the forefront of molecular biology research. - - 2018-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - DIAL-IN - - - H2020-MSCA-IF-2015 - - - 703759 - - - - - University of Worcester - - - EUR 195 454,80 - - - Implementation of a dynamical Pollen Module and the transformations of the pollen including feedbacks in a numerical Weather Forecast Model - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The main goal of the proposed project is to provide an advanced mathematical model (WRF-BioChem) for modelling the emission, dispersion and concentration of bioaerosols at the regional scale. The model will with this - development be able to handle feedback mechanisms between biology, chemistry and weather. The model is developed to go beyond state-of-the-art by developing the mathematical model for oak pollen and by doing it at the species level. The project - supported by a three companion projects on grass pollen, fungal spores (Alternaria) and pathogens – all at species level. These projects deliver the needed resources for detection. As such the mathematical model will be a validated model that will be - generally applicable for bioaerosols including pollen, pathogens and fungal spores. Detection of pollen will be carried out by supporting staff and projects using both traditional methods based on optical detection at the genus level and next - generation sequencing at the species level. This proposal requires multidisciplinary approach to the problem as pollen appearance and behaviour in the air is dependent on many factors, including meteorological conditions, chemical composition of the - atmosphere or surface properties as well as feedbacks between these elements. WRF-Chem currently used in air quality modelling will therefore be adapted for studying transport of bioaerosols in a way consistent with the transport and transformation - of other air pollutants. Until now, no atmospheric model is used for the simulation of pollen at the species level in either Europe or in USA. Also, it will be the first time simulations of oak pollen will be possible in Europe or in USA. Also, it - will be the first time simulations of oak pollen will be possible in Europe. Finally, it will be the first mathematical model that allows for a full feedback between meteorology, chemistry, bioaerosols and the terrestrial biosphere. The model - developments will be implemented in forecasting. - - 2018-05-31, ongoing project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - IPLATFORM - - - H2020-MSCA-IF-2015 - - - 701753 - - - - - WATERFORD INSTITUTE OF TECHNOLOGY - UNIVERSITA DEGLI STUDI DI PERUGIA - UNIVERSITAT POLITECNICA DE CATALUNYA - TTY-SAATIO - KOC UNIVERSITY - UNIVERSITAIR MEDISCH CENTRUM UTRECHT - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM - IMINDS - CONSORZIO NAZIONALE INTERUNIVERSITARIO PER LE TELECOMUNICAZIONI - - - EUR 532 336 - - - Coordinating European Research on Molecular Communications - - - EUR 532 336 - - - Ireland - Italy - Spain - Finland - Turkey - Netherlands - United Kingdom - Belgium - Belgium - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - - In recent years, several research groups have been created in the emerging research area of molecular communications. This is seen as a fundamental enabler for nano-scale networked devices. The heterogeneity of the biological - environments that can host nano-scale communications has produced different proposals (e.g. neuronal networks, molecular diffusion, flow-based carrier mobility) analyzed by means of different research approaches and tools (different analytical - models, simulators, lab experiments). For this reason, the need of integrating research activities at an EU level has emerged. The main objective of the CIRCLE is to integrate islands of heterogeneous research activities in a common research - framework. The nature of the proposal is therefore strategic for the EU research objectives, highly interdisciplinary, inclusive of any input coming from any research activities that can contribute to identifying a research roadmap for the future - years and feasible future exploitation plans. - - 2017-05-31, closed project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-2-2014 - Coordination and Support Activities - - - CSA - Coordination and support action - - - Ireland - - - CIRCLE - - - H2020-FETOPEN-2014-CSA - - - 665564 - - - - - INSTITUTO DE MEDICINA MOLECULAR - UNIVERSIDAD POMPEU FABRA - UNIVERSIDAD DE NAVARRA - TECHNOPHAGE INVESTIGACAO E DESENVOLVIMENTO EM BIOTECNOLOGIA SA - CENTRO ATLANTICO DEL MEDICAMENTO, SA - PROTEODESIGN SL - - - EUR 850 500 - - - Innovative peptides against cancer and pathogenic bacteria, with advances in science, biopharmaceutical drug development, product market targeting, training , and communication. - - - EUR 1 390 500 - - - Portugal - Spain - Spain - Portugal - Spain - Spain - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - INPACT aims at the pre-clinical development of innovative drugs and drug formulations against selected cancers (eg prostate cancer) and pathogenic bacteria (eg S. aureus). The INPACT consortium allies the expertise of both - academic and industrial R&D partners that contribute with their own unique technologies to achieve new drugs that are only possible to develop in an integrative effort. Academic partners have unique knowledge and technologies on supercharged - viral proteins-derived cell-penetrating peptides (eg from Dengue virus) and ultra-resistant cyclic peptides that may be transferred to the industrial partners, which in turn have specialized proprietary technologies on anticancer and/or peptide - drugs’ technologies. The judicious exchange of knowledge among partners will lead to new resistant peptides for trans-barrier delivery of drugs (eg cyclic peptide-drug chimeras) and bacterial killing (both planktonic and biofilms). INPACT includes - four leading academic partners (from Portugal, Spain, Australia, and Brazil) and three consolidated biotech SMEs (one from Portugal and two Spain). - - 2019-01-31, ongoing project - - - 2015-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Portugal - - - INPACT - - - H2020-MSCA-RISE-2014 - - - 644167 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 173 076 - - - Transported cultural landscapes: the role of colonization processes in cultural landscape shaping - - - EUR 173 076 - - - France - - - Research Organisations - - European landscapes are the result of millennia of socio-cultural exchange through trading, migratory and colonial processes. Societies largely dependent to their local ecosystems and when societies move their landscapes move - with them, creating in this way the ‘so called’ transported landscapes. The Mediterranean Sea has been the cradle and contact route of ancient and influential civilizations, but little is known about how cultural exchanges, migratory and colonial - processes contributed to the cultural landscape shaping of Mediterranean environments. This ancient Mediterranean cultural landscape development achieved a universal importance when, during the colonization of America, the transport of European - agro-pastoral landscapes configured a shared cultural landscape heritage between both World regions. Despite its significance in cultural landscape shaping, the study of transported landscapes has been poorly addressed so far. ULISSES project is - designed to (1)identify the environmental impacts, land-uses and landscape changes involved in migratory and colonization processes during the Holocene and (2) evaluate the role of transported landscapes in the shaping of cultural landscapes both in - Europe and overseas. An integrated approach joining multi-proxy palaeoenvironmental analyses (eg. pollen, non-pollen palynomorphs, charcoal analysis, sedimentology), and the study of archaeo-historical sources will be applied in Mediterranean areas - of Spain and California (USA). These have been selected for having ancient colonial relationships and for accounting for a long and intense history of colonial, migratory and socio-economic exchanges. By analyzing the cultural dimension of landscapes - and the mobility of cultural landscapes, ULISSES will significantly contribute to 1)a better understanding of the European Mediterranean cultural landscape heritage, 2) the formation of European identities and cultures and 3) the influence of - European culture and societies in the World - - 2017-09-30, closed project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - France - - - ULISSES - - - H2020-MSCA-IF-2014 - - - 655659 - - - - - THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN - - - EUR 941 760 - - - Political Concepts in the World - - - EUR 1 883 520 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The POLITICO PhD programme will build on the success of the interdisciplinary training provided by the University of Aberdeen’s Centre for Citizenship, Civil Society and the Rule of Law (CISRUL), which specializes in the - global application of political ideas. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2016 - Co-funding of regional, national and international programmes - - - MSCA-COFUND-DP - Doctoral programmes - - - United Kingdom - - - POLITICO - - - H2020-MSCA-COFUND-2016 - - - 754326 - - - - - Netherlands Forensic Institute - - - EUR 177 598,80 - - - Chemical Profiling of Inorganic and Pyrotechnic Explosives - - - EUR 177 598,80 - - - Netherlands - - - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - The criminal law system has shown interest in the recent scientific developments with respect to chemical profiling of explosives. This approach goes beyond explosive material chemical identification, providing key - intelligence to a counter-terrorism or forensic investigation on the basis of chemical clues in the form of impurities and degradation products. Explosive profiling can reveal relationships between samples obtained from a crime scene and material - associated with a suspect. If such profiles can be linked to the production process and the raw materials used such intelligence information can even assist law enforcement in stopping attacks from being successfully executed. However, explosive - profiling is challenging since it requires suitable analytical strategies, unbiased interpretation of the results, substantial sample collections and comprehensive knowledge on the chemical variation of explosives, precursors and environmental - background levels. The main research objective of the PyroProf project is to offer suitable analytical tools for the chemical profiling of inorganic explosives of forensic interest (e.g., ammonium nitrate based and pyrotechnic mixtures) for their use - in forensic casework. This project will yield selective sampling strategies, novel separation methodologies by state-of-the-art CE-MS and IC-MS instruments, complementary statistical approaches and databases with further knowledge on explosive, - precursor, and background compositions useful for forensic interpretation. This outcome will benefit the experienced researcher to boost his career as a professional researcher in the analytical and forensic chemistry fields as well as will have - impact on the European society since the results will be disseminated and used to/by scientific and forensic communities, improving the criminal justice system and the public awareness of the safety and security issued associated with the use of - certain explosives (e.g., legal/illegal consumer fireworks). - - 2019-09-03, ongoing project - - - 2017-09-04 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-SE - Society and Enterprise panel - - - Netherlands - - - PyroProf - - - H2020-MSCA-IF-2016 - - - 747249 - - - - - EUROPEAN UNIVERSITY INSTITUTE - - - EUR 262 269 - - - MAPS – Migrants And People Smugglers: A Comparative Study of Smuggling Networks in the Eastern Mediterranean and the Central American corridors - - - EUR 262 269 - - - Italy - - - Higher or Secondary Education Establishments - - To what extent is human smuggling a criminal enterprise driven by solidarity and cooperation? This is the question that my project “MAPS – Migrants And People Smugglers” addresses through a comparative study – of the Eastern - Mediterranean and the Central American smuggling corridors. Having almost concluded my research in the Eastern Mediterranean corridor, the project will concentrate almost exclusively on the Central American route in order to identify similarities and - differences in the organizational structures of smuggling networks, the smuggler-migrant relationship, and the profile of the facilitators. MAPS seeks to make a contribution to studies on Human Smuggling and Irregular Migration, where there is a keen - interest in – yet still insufficient knowledge about – the interaction between migrants and facilitators and where criminological perspectives still dominate the debate. MAPS adopts a critical perspective and departs from the idea that smugglers obey - only to a profit making logic. Inviting instead for a more complex understanding of their roles, it argues that human smuggling is embedded within ethnic networks and local economies, which are grounded on deep notions of solidarity and reciprocity. - By expanding current knowledge around smuggling and its related policies, the project also aims to provide an empirical platform for policy engagement. In order to achieve its research aims, I will be based at the San Diego State University (SDSU), - located at the proximities of the US/Mexican border and renown for being a centre of excellence on migratory trends from Central American. Here, I will be trained in Critical Criminology, Hispanic Studies and Social Network Analysis under the - supervision of Prof Sheldon Zhang. Upon returning to my European host institution, the EUI, I will bring my new skills and further improve my policy and dissemination training under the supervision of Prof Triandafyllidou at the Cultural Pluralism - Area of the GGP (EUI). - - 2020-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Italy - - - MAPS - - - H2020-MSCA-IF-2016 - - - 752144 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 195 454,80 - - - Thessaly under the Kings: Religion, Society and the Politics of Multiculturalism in Mainland Greece - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - My project titled 'Thessaly under the Kings: Religion, Society and the Politics of Multiculturalism in Mainland Greece’ examines the reorganization of sacred space, the cult practices and the religious beliefs attested in - Thessaly from the mid-fourth century to the second century BC. The evidence will be discussed in terms of continuity and change, from the gradual modification of the Thessalian geopolitical and urban landscapes, which was exercised by the Macedonian - rulers, to the annexation of the region into the Hellenistic Kingdom of Macedonia, down, finally, to the decline of the Macedonian power and the emergence of Roman control in the region. - - 2017-09-30, closed project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - THESUNKIN - - - H2020-MSCA-IF-2014 - - - 658573 - - - - - INSTITUTO DE ASTROFISICA DE CANARIAS - - - EUR 170 121,60 - - - The DIffuse Galaxy Expansion SignaTures In Various Observables project: understanding the emergence of diffuse, low surface brightness galaxies and the link to their dark matter haloes - - - EUR 170 121,60 - - - Spain - - - Research Organisations - - I propose to carry out the ‘DIffuse Galaxy Expansion SignaTures In Various Observables’ (DIGESTIVO) project, a joint theoretical and observational effort alongside observers at the Instituto de Astrofisica de Canarias (IAC), - to study the evolution and formation of Low Surface Brightness galaxies (LSBs), including the recently discovered Ultra-Diffuse Galaxies (UDGs). LSBs are extremely dark matter dominated, faint objects hardly distinguishable from the night sky. In the - last decade it has became clear that large numbers of LSB galaxies exist, opening a new window on galaxy evolution and formation. How do such diffuse galaxies form and evolve? How are they linked to their dark matter haloes, and how do they fit - within the current cosmological model of galaxy formation? - - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - DIGESTIVO - - - H2020-MSCA-IF-2016 - - - 748213 - - - - - THE SAINSBURY LABORATORY - THE SAINSBURY LABORATORY - JOHN INNES CENTRE - - - EUR 2 491 893 - - - Retooling plant immunity for resistance to blast fungi - - - EUR 2 491 893 - - - United Kingdom - United Kingdom - United Kingdom - - - Research Organisations - Research Organisations - Research Organisations - - Plant NLR-type immune receptors tend to have a narrow spectrum of pathogen recognition, which is currently limiting their value in agriculture. NLRs can recognize pathogen effectors through unconventional domains that have - evolved by duplication of an effector target followed by fusion into the NLR. One NLR with an integrated domain is the rice resistance protein Pik-1, which binds an effector of the blast fungus Magnaporthe oryzae via its Heavy-Metal Associated (HMA) - domain. We solved the crystal structure of the HMA domain of Pik-1 in complex with a blast fungus effector and gained an unprecedented level of detail of the molecular interactions that define pathogen recognition. This led to the overall aim of this - proposal to generate a complete picture of the biophysical interactions between blast fungus effectors and HMA-containing cereal proteins to guide the retooling of the plant immune system towards resistance to blast diseases. M. oryzae is a general - cereal killer that infects wheat, barley and rice, which are staple food for a majority of the world population. The central hypothesis of the proposed research is that mutations in cereal HMA-containing proteins will result in broad-spectrum - resistance to blast fungi. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - BLASTOFF - - - ERC-2016-ADG - - - 743165 - - - - - FUNDACION PARA LA INVESTIGACION DEL HOSPITAL UNIVERSITARIO LA FE DE LA COMUNIDAD VALENCIANA - - - EUR 257 191,20 - - - CD8+ T cell metabolism in anti-tumor response - - - EUR 257 191,20 - - - Spain - - - Research Organisations - - Although cancer immunotherapy has achieved significant breakthroughs in recent years that has positioned it as the most promising approach to treat cancer, its overall efficacy remains limited in the majority of patients. - Nutrition-deprived conditions at tumor microenvironment poses significant metabolic challenges to tumor-infiltrating lymphocytes which may contribute to failure of anti-tumor activity. The main objective of the Immunometabolomics project is to - understand metabolism in CD8+ T cells, during active effector T cell development and exhaustion, using approaches that go beyond current research which have been mostly focused on glucose/energy metabolism thus disregarding the relevance of anabolic - and redox reactions that are crucial in correct cellular function and proliferation. Open-ended metabolomics and metabolic flux analysis studies, in combination with genetic, nutrition and pharmacological manipulations will be employed to study areas - of metabolism that have not been previously extensively studied in CD8+ T cells including 1C metabolism. The characterization of metabolism in CD8+ T cells will be gradually performed in models of higher complexity and physiological and clinical - relevance from in vitro, to in vivo in genetically engineered mouse models of lung cancer and finally in lung cancer patients. Through understanding CD8+ T cell metabolism, and its modulation in cancer within tumor microenvironment, we aim to develop - a basic science foundation for increasing immunotherapy efficiency in cancer through the use of complementary nutritional and/or metabolism-targeted pharmacological approaches. - - 2020-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Spain - - - Immunometabolomics - - - H2020-MSCA-IF-2016 - - - 751423 - - - - - SCUOLA NORMALE SUPERIORE - - - EUR 168 277,20 - - - Gut microbiota impact on brain development and plasticity. - - - EUR 168 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - The gut microbiota is characterized by a variety of microorganisms that live in symbiosis with our body and that play a key role in host immune system development and metabolism. Studies in adult germ-free mice suggested the - influence of gut commensals on emotional behaviors and stress responses. However, the exact mechanism through which these bacteria affect brain function is largely undiscovered and, their impact on brain development is still a relatively unexplored - territory. In my project I propose to investigate how the gut microbiota modulates brain development and plasticity using the established model of mouse developing visual cortex. To find if development and environmental stimuli affect intestinal - bacteria, the gut microbiome of mice reared in standard condition (ST) or in an enriched environment (EE) that is known to modulate visual development, will be analyzed at different ages: before weaning (P15), after weaning (P28) and in adulthood - (P60) providing for the first time a developmental timeline of the gut microbiota in mice. Then, I will perturb the microbiota composition through antibiotic treatment (ABX) or fecal transplantation (FT) in ST and EE mice, and assess visual cortical - function maturation and ocular dominance plasticity. Dendritic spine dynamics analyzed by in vivo two-photon imaging and formation of inhibitory and excitatory neurons will be assessed in the primary visual cortex (V1) as morphological biomarkers of - visual cortical development. Finally, in order to find the molecular mechanisms and mediators of gut commensals effect on neuronal circuits, I will perform a transcriptome analysis in V1 of ST and EE mice treated with ABX, or subjected to FT. My - research will bring a substantial advancement in the field, revealing how the early interaction between microbiome and host can shape cortical functions, hopefully enabling the discovery of biomarkers for facing neurodevelopmental and psychiatric - diseases. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - GaMePLAY - - - H2020-MSCA-IF-2016 - - - 749697 - - - - - UNIVERSITAIR MEDISCH CENTRUM UTRECHT - - - EUR 177 598,80 - - - Investigating the recognition of a novel ligand by gamma-delta T cells and the translation of this interaction into molecules for future cancer immunotherapy - - - EUR 177 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Gamma-delta (gd-)T cells are a fast acting subset of T cells that recognize a wide variety of ligands. In contrast to alpha-beta T cells they are not restricted to classical peptide-MHC antigens. Our preliminary data on a gd-T - cell clone shows selective recognition of tumour cells mediated through a novel ligand. - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Netherlands - - - gdTCR-Ligand - - - H2020-MSCA-IF-2016 - - - 749010 - - - - - AALTO-KORKEAKOULUSAATIO - AALTO-KORKEAKOULUSAATIO - - - EUR 2 499 999 - - - Field driven materials for functions, dissipation, and mimicking Pavlovian adaptation - - - EUR 2 499 999 - - - Finland - Finland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - During the recent years, biological materials have extensively inspired materials scientists towards new properties, e.g., for composites, photonics, and wetting. The future grand challenge is to mimic biological active - materials towards new properties that commonly have not been connected with man-made materials. Due to the biological complexity, conceptually new approaches are needed in materials science. In the project DRIVEN, field-driven dissipative - out-of-equilibrium self-assemblies are developed in the colloidal and molecular scale. In the proposal, instead of using chemical fuels to drive dissipative self-assemblies, which is ubiquitous in Nature, imposed fields are here used to drive the - system out-of-equilibrium towards new assemblies and functions. The project show steps with growing risks towards highly ambitious new materials mimicking aspects from active biological materials. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Finland - - - DRIVEN - - - ERC-2016-ADG - - - 742829 - - - - - DEUTSCHES KREBSFORSCHUNGSZENTRUM - DEUTSCHES KREBSFORSCHUNGSZENTRUM - - - EUR 2 500 000 - - - Endogenous barcoding for in vivo fate mapping of lineage development in the blood and immune system - - - EUR 2 500 000 - - - Germany - Germany - - - Research Organisations - Research Organisations - - The immune system is a complex ensemble of diverse lineages. Studies on in-vivo-hematopoiesis have until now largely rested on transplantation. More physiological experiments have been limited by the inability to analyze - hematopoietic stem (HSC) and progenitor cells in situ without cell isolation and other disruptive manipulations. We have developed mouse mutants in which a fluorescent marker can be switched on in HSC in situ (inducible fate mapping), and traced HSC - lineage output under unperturbed conditions in vivo. These experiments uncovered marked differences comparing in situ and post-transplantation hematopoiesis. These new developments raise several important questions, notably on the developmental fates - HSC realize in vivo (as opposed to their experimental potential), and on the structure (routes and nodes) of hematopoiesis from HSC to peripheral blood and immune lineages. Answers to these questions (and in fact the deconvolution of any tissue) - require the development of non-invasive, high resolution barcoding systems. We have now designed, built and tested a DNA-based barcoding system, termed Polylox, that is based on an artificial recombination locus in which Cre recombinase can generate - several hundred thousand genetic tags in mice. - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - BARCODED-CELLTRACING - - - ERC-2016-ADG - - - 742883 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - UNIVERSITY OF LEICESTER - - - EUR 1 933 165 - - - Feeding Anglo-Saxon England: The Bioarchaeology of an Agricultural Revolution - - - EUR 1 933 165 - - - United Kingdom - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - By the time of the Norman Conquest in 1066, England’s population was again comparable to that of Roman Britain and included substantial urban centres. By 1200, England was more densely populated than ever before. Such - population growth was mirrored across much of Europe. It drove the expansion of towns and markets and was fed, literally, by an increase in agricultural productivity that involved a fundamental reorganization of the countryside. The social, economic - and demographic consequences of this reorganization were so far-reaching that it has often been described as an ‘agricultural revolution’. At the heart of this proposal is the question, how and when was this revolution achieved? FeedSax will effect a - breakthrough in understanding this critically important period in Europe’s agricultural history by generating new, direct evidence for changing land-use from the excavated remains of crops, animals and farms. - - 2021-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - FeedSax - - - ERC-2016-ADG - - - 741751 - - - - - KUNGLIGA TEKNISKA HOEGSKOLAN - KUNGLIGA TEKNISKA HOEGSKOLAN - - - EUR 2 461 947 - - - Wood Nanotechnology for Multifunctional Structures - - - EUR 2 461 947 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - "Materials tend to be either structural or functional. Here focus is on biobased composites combining both aspects, using nanostructured wood templates. Wood is the most widely used biobased material for load-bearing - structures, but the range of achievable properties and functions can still be increased. The objective is to develop scalable nanotechnology for wood structures, utilizing its nanocellulosic skeleton. Processing and materials design concepts are - developed in the form of a wood nanotechnology toolbox. Focus is on transparent wood for engineering applications, a concept pioneered in my laboratory. Transparent wood can combine load-bearing properties with photonics functions and light weight. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Sweden - - - WoodNanoTech - - - ERC-2016-ADG - - - 742733 - - - - - FORSCHUNGSINSTITUT FUR MOLEKULARE PATHOLOGIE GESELLSCHAFT MBH - FORSCHUNGSINSTITUT FUR MOLEKULARE PATHOLOGIE GESELLSCHAFT MBH - - - EUR 2 325 659 - - - Understanding the evolution of regeneration-permissive gene expression and positional memory in Axolotl limb regeneration - - - EUR 2 325 659 - - - Austria - Austria - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Molecular studies of development in diverse animal models have revealed the remarkably conserved set of morphogens governing growth and patterning of body axes and organ fields. Equally astounding is the diversity of form and - function arising from the implementation of these morphogens. The systematic analysis of well-defined traits in closely related species has revealed how changes in gene regulatory sequences and their trans-acting factors have yielded diversity. An - important future challenge is to understand, at the genome level, the evolution of animal form in situations where such a rich set of closely related species may not be available. - - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Austria - - - RegGeneMems - - - ERC-2016-ADG - - - 742046 - - - - - TECHNISCHE UNIVERSITEIT EINDHOVEN - - - EUR 165 598,80 - - - Liquid Phase Electron Microscopy of Magnetite - - - EUR 165 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Liquid Phase Electron Microscopy (LPEM) is a state-of-the-art analysis technique for real-time observations of nanoscale processes in liquids. As a research tool, it is unique in its ability to observe material formation - pathways in complex environments. Consequently LPEM is expected to solve grand challenges in materials science; however, several obstacles need to be overcome before this technique can fully impact the whole materials science community. In the - proposal LPEMM, I intend to address these multidisciplinary problems through the study of an ideal, but industrially relevant material system, namely magnetite. Magnetite is the most magnetic naturally occurring substance on earth, and of great - technological interest in areas such as water purification, biomedicine and data storage. The magnetic properties of magnetite are determined by particle size, shape and organization, which in Nature is controlled though the process of - biomineralization. In Magnetotactic bacteria biomineralizations occurs in confined, complex compartments called magnetosomes. I will replicate this environment inside the electron microscope and record the process with nanometer resolution, providing - the first ever real-time videos of the magnetite formation. In collaboration with an industrial partner FEI Company, I will determine optimal microscope configuration and imaging conditions for LPEM based on particle motion, contrast and liquid layer - thickness. The proposed research will provide a unique insight into magnetite biomineralization allowing the design of new synthetic routes to form magnetite under ambient conditions, with control over particle size, shape and organization. In a - broader context summation of this research will provide a clear platform for the investigation of material formation in complex environments by LPEM; thereby obtaining unprecedented details on the formation pathway and establishing new synthetic - routes to complex materials. - - 2019-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Netherlands - - - LPEMM - - - H2020-MSCA-IF-2016 - - - 748105 - - - - - RUHR-UNIVERSITAET BOCHUM - RUHR-UNIVERSITAET BOCHUM - - - EUR 1 998 717 - - - Dynamics in Buddhist Networks in Eastern Central Asia, 6th-14th Centuries - - - EUR 1 998 717 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The objective of this proposal is to create a new framework to enable understanding of the complexities in the dynamics of cultural encounter and religious transfer in pre-modern Eastern Central Asia—the vast area extending - from the Taklamakan desert to Northeast China. This region was the crossroads of ancient civilisations. Its uniqueness was determined by complex dynamics of religious and cultural exchanges gravitating around an ancient communication artery, known as - the Silk Road. Buddhism was one major factor in this exchange; its transfer predetermined the transfer of adjacent aspects of culture. The religious exchange involved a variety of cultures and civilisations, which were modified and shaped by their - adoption of Buddhism. This process overrode the ethnic and linguistic boundaries of the Buddhist universe. One specific aspect of this process was the rise of the local forms of Buddhism. This project intends to investigate such Buddhist - localisations between the 6th–14th centuries. - - - 2022-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - BuddhistRoad - - - ERC-2016-COG - - - 725519 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 995 354 - - - Microfluidic Approaches mimicking BIoGeological conditions to investigate subsurface CO2 recycling - - - EUR 1 995 354 - - - France - France - - - Research Organisations - Research Organisations - - The management of anthropogenic CO2 will be one of the main challenges of this century given the dramatic impact of greenhouse gases on our living environment. A fascinating strategy to restore the advantages of stored CO2 as - a raw material would be to consider a slow biological upgrading process of CO2 in deep geological formations. - - - 2022-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - France - - - Big Mac - - - ERC-2016-COG - - - 725100 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - NATURAL ENVIRONMENT RESEARCH COUNCIL - - - EUR 2 817 554 - - - WArm Climate Stability of the West Antarctic ice sheet in the last INterglacial (WACSWAIN) - - - EUR 2 817 554 - - - United Kingdom - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - Recent papers predict the loss of most of the West Antarctic Ice Sheet (WAIS) by 2500 if CO2 emissions and rising global temperatures are not controlled. It is critical to test whether the models making such worrying - predictions are realistic. I will do this by obtaining new data from the last interglacial (LIG, 130,000-115,000 years ago) to assess the response of the WAIS to comparable warmth. - - - 2022-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - WACSWAIN - - - ERC-2016-ADG - - - 742224 - - - - - ROYAL COLLEGE OF SURGEONS IN IRELAND - ROYAL COLLEGE OF SURGEONS IN IRELAND - - - EUR 1 781 622,96 - - - Investigating the meanings and mechanisms of psychotic experiences in young people: a novel, mixed-methods approach - - - EUR 1 781 622,96 - - - Ireland - Ireland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Up to one fifth of young people have had the experience of psychotic symptoms, such as hearing voices when there is no-one around, or seeing visions. We now know that young people who experience these symptoms are at increased - risk of developing psychotic disorders in adulthood. We also know that these young people are at higher risk of a range of co-morbid disorders such as depression and anxiety, and particularly suicidal behaviours. On the other hand, many of these - young people will remain well and, for them, the psychotic experiences were merely a transitory phenomenon. - - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Ireland - - - iHEAR - - - ERC-2016-COG - - - 724809 - - - - - THE HEBREW UNIVERSITY OF JERUSALEM - THE HEBREW UNIVERSITY OF JERUSALEM - - - EUR 150 000 - - - A novel pharmaceutical treatment for nonalcoholic fatty liver disease - - - EUR 150 000 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Development of anti-microRNA therapeutic for nonalcoholic fatty liver disease - - 2018-11-30, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Israel - - - NAFLDcure - - - ERC-2016-PoC - - - 737590 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 149 963 - - - Aligned Roll-to-Roll Shear Coating of Nanotubes - - - EUR 149 963 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Carbon Nanotubes (CNTs) are considered to be one of 21st century’s most promising materials and over the past decade, tremendous scientific advances have been achieved in the synthesis and processing of these materials. - However, the uptake of CNTs by high-tech industry is hampered by a lack of high-throughput processes to structure CNTs into aligned and densely packed assemblies. This is key to fabricate next generation CNT devices, and to date, the CNT community is - still struggling to achieve this, especially over large areas. - - - 2018-12-31, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - ARENA - - - ERC-2016-PoC - - - 737627 - - - - - THE HEBREW UNIVERSITY OF JERUSALEM - THE HEBREW UNIVERSITY OF JERUSALEM - - - EUR 150 000 - - - TIGIT therapy for cancer treatment - - - EUR 150 000 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Treating tumors with immune-related therapies is one of the most exciting and promising advancements made in the past decade. Cancer immunotherapy drugs have captured nearly 50% of the overall oncology drugs market. TIGIT is - an important checkpoint inhibitory receptor discovered by our group in 2009. It is constitutively expressed by various immune cells and its expression is further increased on tumor infiltrating lymphocytes (TILs). TIGIT recognizes two main ligands, - PVR and Nectin2 that are highly expressed on various tumors. Blockage of TIGIT on TILs either alone or in combination with another checkpoint inhibitory receptor, PD-1, leads to increased T and Natural Killer (NK) cell activity in vitro and inhibited - tumor growth in vivo. We developed 9 different anti-TIGIT mAbs during my BacNK ERC advanced grant and previously. In the POC grant TIGITtherapy, which already attracted interest from several bio pharma companies, I propose testing which of the 9 - anti-TIGIT mAbs and TIGIT-Ig are able to antagonize TIGIT activity. - - 2018-12-31, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Israel - - - TIGITtherapy - - - ERC-2016-PoC - - - 721317 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 1 462 304 - - - Global Firms and Global Value Chains: Measurement and Mechanisms - - - EUR 1 462 304 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The growing fragmentation of production across firms and countries has revolutionized international trade in recent decades. Firms today choose which production stages to conduct themselves and which to outsource to other - parties, which to complete at home and which to offshore abroad. Known as global value chains (GVCs), this phenomenon creates new challenges and opportunities for individual firms and aggregate economies. Of primary policy interest are the - implications of GVCs for growth, the transmission of shocks across firms and borders, and the design of economic policies. Yet academic research has faced two major challenges: poor measurement and poorly understood mechanisms. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - GLOBALFIRMS - - - ERC-2016-COG - - - 724880 - - - - - KOBENHAVNS UNIVERSITET - - - EUR 200 194,80 - - - Modelling Arctic Biogenic Volatile Organic Compounds emissions (MABVOC) - - - EUR 200 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - Arctic is warming at approximately twice the global speed, which could result in drastic changes in the arctic biosphere as well as its potential feedbacks to the atmosphere. Several important but uncertain feedbacks are - related to biogenic volatile organic compounds (BVOC) emissions from arctic plants and high organic soils. BVOC influence climate systems through changing atmospheric compositions (oxidant and aerosols); however, the magnitudes and directions of - these feedbacks are still poorly quantified for the Arctic. This project, MABVOC, aims to quantify BVOC emissions for the pan-Arctic region by using a process-based dynamic ecosystem model (LPJ-GUESS), combined with leaf, soil and ecosystem levels - observations from the Arctic, and to further predict potential changes of emissions under climate change. A series of model developments will be proposed in this project to explicitly consider arctic plants emission features as well as soil BVOC - dynamics. The host group, conducting large and novel field observations about arctic BVOC, will provide needed field data and frontier understanding that will be implemented in the model. I will combine my expertise in arctic ecosystem modelling to - numerically link BVOC fluxes with different ecosystem processes, which enables me to provide quantifications of different factors’ impacts on emissions to the host group. The high degree of complementary expertise between the host and I will - guarantee the quality and smoothness of this project. The updated emission estimates from the Arctic will pave a way for reassessing arctic BVOC-mediated feedbacks to the climate system. Furthermore, the proposed model developments in this project - will be transferable to the larger modelling community to reduce uncertainties in arctic applications. The integration of experiences between field investigators and ecosystem modellers in this project will lead to a productive and valuable exchange - of knowledge on both sides. - - 2018-11-30, ongoing project - - - 2016-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - MABVOC - - - H2020-MSCA-IF-2015 - - - 707187 - - - - - WEIZMANN INSTITUTE OF SCIENCE - WEIZMANN INSTITUTE OF SCIENCE - - - EUR 2 000 000 - - - Learning and Anxiety in Amygdala-based Neural Circuits - - - EUR 2 000 000 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Major advances were made in understanding circuits that underlie aversive emotional learning. The majority gained by using classical associative models, mainly tone/context-shock conditioning. Failure to extinguish the - response or to discriminate from other safe stimuli (generalization), form two main animal models for human anxiety-disorders and post-traumatic-stress. These simple yet powerful approaches enabled cutting-edge techniques in rodents to unveil - amygdala circuitry and its connectivity with the medial-prefrontal-cortex. Yet, we have less understanding of the mechanisms that underlie elaborated behavioural models of mal-adaptive behaviour, as well as less understanding of neural codes and - computations in the evolutionary-expanded primate amygdala. Our lab recently embarked on exploring these venues by pioneering physiological studies of generalization and extinction protocols in primates. The goal of the current project is to develop - behavioural models of complex learning and maladaptive behaviour, and then examine and shed light on the underlying computations in primate amygdala-PFC circuit. We design a novel rule-based learning task, and examine its acquisition, extinction, - generalization and exploration-exploitation trade-off in dangerous environments. Specifically, the concepts of rule learning and exploration-exploitation tradeoff form novel insights and aspects of [mal-]adaptive behaviours, and will suggest new - animal models of learned anxiety. We record dozens of neurons in the amygdala and prefrontal-cortex simultaneously using deep multi-contact arrays, supplemented by stimulation to address functional connectivity, and development of modelling - approaches for the behaviour and neural codes. We posit that the development of more [complex] models is crucial and the next logical step in achieving translation of animal models of anxiety disorders, as well as in understanding basic mechanisms - behind the rich repertoire of emotional behaviours. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Israel - - - LearnAnx_CircAmyg - - - ERC-2016-COG - - - 724910 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS - - - EUR 251 857,80 - - - Acoustical and Canonical Fluid Dynamics in numerical general relativity - - - EUR 251 857,80 - - - United Kingdom - United States - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The motion of strongly gravitating fluid bodies is described by the Euler-Einstein system of partial differential equations, combining fluid dynamics with general relativity. Centuries after their advent, the solution to these - equations remains mathematically and computationally difficult, and the break-down of well-posedness on the boundary interface between fluid and vacuum remains a challenging open problem. The problem manifests itself in numerical simulations of - binary neutron-star inspiral. The program will focus on formulating and implementing novel, well-posed Hamiltonian hydrodynamic schemes, suitable for inspiral simulations and gravitational-wave detector applications, with promising mathematical and - computational applications in academia and industry. The scheme will use a variational principle by Carter-Lichnerowicz stating that barotropic fluid motions are conformally geodesic, a corollary of Kelvin's circulation theorem stating that initially - irrotational flows remain irrotational, and Christodoulou's acoustic metric approach adopted to 3+1 numerical general relativity, in order to evolve the canonical momentum of a fluid element via Hamilton's equations. The recent observation of the - inspiral and merger of binary black holes by the LIGO-Virgo collaboration, which marked the beginning of the era of gravitational wave astronomy, makes this work very timely: additional observations from binary neutron star or black hole–neutron star - binary mergers are anticipated over the next years. The proposed research represents a coherent program aimed at mathematically and computationally exploring the theory of neutron stars, in order to improve our understanding of fundamental physical - laws and reveal how nature operates on scales where our current understanding breaks down. Improvements in calibrated semi-analytical neutron-star gravitational waveforms can be directly deployed in the LIGO-Virgo search and parameter estimation - pipelines. - - 2020-08-14, ongoing project - - - 2017-08-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - ACFD - - - H2020-MSCA-IF-2016 - - - 753115 - - - - - KOBENHAVNS UNIVERSITET - KOBENHAVNS UNIVERSITET - - - EUR 2 211 015 - - - Self Organization in Competition and Diversity - - - EUR 2 211 015 - - - Denmark - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - "At all scales, biology presents an astounding diversity of discrete states or species that coexist with each other long times. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Denmark - - - SOURCE - - - ERC-2016-ADG - - - 740704 - - - - - STICHTING VU - - - EUR 177 598,80 - - - Stepping forward in understanding the Metabolic Cost of Human Walking - - - EUR 177 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - The mechanisms underlying metabolic cost of walking are unclear. This is important not only because they provide fundamental insight in human movement, but they are also essential to reduce increased cost of walking in the - elderly and impaired. To understand these mechanisms, it is required to know the link between energetics at the human level and the energetics at the muscle level. Whereas the energetics at the human level is experimentally accessible, that at the - muscle level is not. Current estimations greatly overestimate actual metabolic cost and hence there is no basis understanding metabolic cost of walking. - - - 2017-03-31, closed project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Netherlands - - - Metabolic cost of walking - - - H2020-MSCA-IF-2014 - - - 655457 - - - - - THE UNIVERSITY OF BIRMINGHAM - TECHNISCHE UNIVERSITEIT EINDHOVEN - UNIVERSIDADE DO MINHO - JYVASKYLAN YLIOPISTO - NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO - STICHTING VU - ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA - PERSONAL GENOMICS SRL - - - EUR 2 873 941,92 - - - Physical Activity and Nutrition INfluences In ageing - - - EUR 2 873 941,92 - - - United Kingdom - Netherlands - Portugal - Finland - Netherlands - Netherlands - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Life expectancy is increasing dramatically, but the period of good health (healthspan) enjoyed by most is not keeping pace, with implications for health, social care, and pensions resulting in estimated costs more than - doubling by 2050. Thus, understanding the many factors that contribute to healthy ageing versus frailty, and validating interventions and influencing policy to promote healthy ageing is a cross-cutting research priority in Europe. Given the - considerable impact of lifestyle factors on healthy ageing and disease, there is a surprising lack of innovative multi-disciplinary training and research examining the influence of physical activity and nutrition on age-related changes at gene to - societal level. PANINI will address this gap by coordinating research laboratories across Europe to focus on cutting-edge ageing and health research through training 11 ESRs across scientific disciplines to create a holistic approach to the challenge - of ageing in the 21st Century. PANINI is a European Training Network with 8 world-leading beneficiaries working on Healthy Ageing and 10 non-academic partners carefully selected for quality and range of sectors. These vary in size including 1 large - nutrition company, 5 SMEs, 2 charities, 1 healthcare partnership and 1 EU Joint Research Centre. PANINI’s vision is to implement multidisciplinary cross-sectoral research and training of a new cohort of researchers taking a radically innovative - approach to overcome the challenge of unhealthy ageing. The main goals of PANINI are to: integrate expertise from basic biomedical science and technology to applied clinical practice; standardise measurements across the network to create a toolkit - and shared dataset; provide multidisciplinary training secondments to expose ESRs to healthcare and industry research settings and other laboratories; disseminate widely the shared and individual project findings; and use these to develop a policy - document to promote healthy ageing in Europe. - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - PANINI - - - H2020-MSCA-ITN-2015 - - - 675003 - - - - - KATHOLIEKE UNIVERSITEIT LEUVEN - Stichting Sanquin Bloedvoorziening - PROTOBIOS OU - ICOSAGEN AS - - - EUR 1 464 397,92 - - - Innovative training network: Immunoprofile-directed stratification of patients with the autoimmune disorder thrombotic thrombocytopenic purpura - - - EUR 1 464 397,92 - - - Belgium - Netherlands - Estonia - Estonia - - - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The PROFILE Innovative European Industrial Doctoral programme will develop improved tools for stratification of patients with the autoimmune disorder acquired thrombotic thrombocytopenic purpura (TTP). Patient stratification - is needed in order to further develop personalized medicine approaches for human disorders. Therefore, a detailed understanding of the disease at the molecular level is needed. Furthermore, implementation of a robust set of novel biomarkers is - essential for stratification of patients. Also, highly flexible platforms to rapidly develop novel therapeutics are crucial to further boost the field of personalized medicine. The research program is embedded in a unique translational training - program, which emphasizes clinical needs as a driving force for development of novel, innovative diagnostics and therapeutics (for personalized medicine). There is intersectoral knowledge transfer between academia and companies at the European level - as 6 different EU Member states are involved in the network either as beneficiary or partner organization. The PROFILE network will allow 6 early stage researchers to follow this unique translational training. They will be trained in the clinic to - identify clinical needs, in academia where they will contribute to a scientifically ambitious project and in the non-academic sector where they will be trained in a novel technologies and commercializing bioassays endowing them with an unique PROFILE - for further advancing personalized medicine in Europe. - - 2019-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-EID - Marie Skłodowska-Curie Innovative Training Networks (ITN-EID) - - - MSCA-ITN-EID - European Industrial Doctorates - - - Belgium - - - PROFILE - - - H2020-MSCA-ITN-2015 - - - 675746 - - - - - STICHTING VU - - - EUR 165 598,80 - - - Institutional Innovation for Adapting to Climate Change in Water Governance within Cities - - - EUR 165 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - This research will address the problem of the currently insufficient level of institutional innovation in water governance systems in the context of climate change. Climate change creates urgent need for adaptive water - governance that can anticipate and respond to increasing pressures on water systems within human society. Cities are a key locus of attention. Institutional innovation is needed (e.g. policy change, new organisational setups, new inter-organisational - arrangements). However, knowledge of the types of institutional innovation required and the mechanisms (e.g. political, institutional) by which it emerges is lacking. Therefore I will address the question: What types of institutional innovation are - required for adapting to climate change in water governance within cities, and how can we better understand why and how they emerge? This will involve: (1) global assessment of institutional innovation in water governance in 30 cities across 6 - continents to identify broad patterns and best practices across the world; (2) comparative case study analysis of 3 ‘innovative’ cities across 3 continents in contrasting global contexts to attain deeper understanding of dynamics underpinning - innovation; and (3) dissemination of results and policy recommendations to enable innovation in cities in Europe and globally. By addressing this urgent research and policy problem, the MCSA fellowship will enable me to develop new expertise, - academic and policy networks, and research profile that will position me as a leading emerging scholar in the field of water governance and climate change adaptation. The research will contribute to the knowledge based economy of Europe by providing - critical new academic and policy insights to safeguard against water-related vulnerabilities in cities under climate change, and contribute to addressing two of the European Commission’s ‘Grand Challenges’ (i.e. climate action; and innovative and - reflective societies). - - 2017-10-18, closed project - - - 2015-10-19 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - INNOVCITIES - - - H2020-MSCA-IF-2014 - - - 659065 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CHARITE - UNIVERSITAETSMEDIZIN BERLIN - - - EUR 2 547 762 - - - IMMUNOBIOLOGY OF LYMPHOID STROMAL CELLS - - - EUR 2 547 762 - - - France - France - Germany - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - - In 1984, Nossal wrote ‘‘A readership consisting of primarily anatomists has every right to question the favorite sport of research workers in cell immunology. This is to take a lymphoid tissue and totally destroy its beautiful - and elaborately designed architecture to obtain simple cell suspension of lymphocytes, which are then asked to do more or less all the jobs of the original anatomic masterpiece’’. Growing evidence that lymph node (LN) stromal cells control the - motility, activation and survival of lymphocytes has reinforced this view. These architectural cells assemble in 3D networks that regulate LN homeostasis and control its ability to remodel during inflammation. Understanding stromal cell biology is - thus mandatory to our full comprehension of the immune system but this ambitious objective is technically challenging. As the complexity of the LN cannot be modelled in culture, knowledge gained from in vitro experiments is limited and will not - address many relevant questions related to the biology of LN stromal cells, in particular (i) the elucidation of their origin and the precursor/product relationships that link them, (ii) the determination of their behavior in inflamed LNs and (iii) - their subsequent fate in LNs that have returned to homeostasis. To this aim, I have developed several original, cutting-edge multicolor fluorescent reporter mouse models and computational modeling approaches to map the fate of single stromal cells - and their progeny in situ. Using this innovative approach, my group will investigate the spatio-temporal behavior and molecular cues that orchestrate the development and dynamics of the major LN stromal cell populations in vivo, at steady state and - under inflammatory conditions, at the single cell level. Because the proposed studies will unravel the precursor/product relationships linking the various stromal cell types, we anticipate to provide the first “Phylogenetic tree” of LN stromal cell - development and remodeling. - - 2020-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - France - - - STROMA - - - ERC-2014-CoG - - - 647257 - - - - - STICHTING VU - - - EUR 177 598,80 - - - Decoding the neural mechanism of human spatial cognition using behavioural and hemodynamic signals - - - EUR 177 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - The aim of this research is to understand space constancy, that is the mechanisms used by the brain to build a stable and continuous percept of our environment despite frequent movements of our sensory receptors (eyes, ears). - For example, each time we move our eyes, the image of the outside world sweeps across the retina, yet we see the world as stable. Studies using single cell recording in animals have shown that some visual neurones predict what the world will look - like after an eye movement by remapping their receptive fields to the place they will occupy following the movement. In my previous studies I developed behavioural tools that allowed me to model remapping in human as an attentional process. Even - though my findings in humans were largely consistent with the results obtained from single cell recordings in animals, there was no possible way to establish a direct link between these data. Recent methodological advances in functional imaging, both - in terms of techniques and data analysis make this possible. By combining my tools with novel imaging analysis of human population receptive fields, I aim to determine the mechanisms our brains use to stabilise our percept of the world for visual and - auditory objects. Using hemodynamic (fMRI) and behavioural (gaze recording) signals I will decode the organisation of the multi-sensory spatial maps. I aim to determine the role of attention for space constancy, to establish innovative methods and - procedures for investigating human spatial cognition, and to reconcile human and animal neurosciences findings by providing precise neural information of the maps and the neural mechanisms of human spatial navigation. This interdisciplinary project - will constitute a unique opportunity to combine my expertise with state-of-the-art methods. I will have the chance to expend my skills, putting me on the best track to pursue a future independent research career with a multi-faceted profile of - psychologist and neuroscientist. - - 2019-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - DecodeRemapping - - - H2020-MSCA-IF-2015 - - - 704537 - - - - - STICHTING VU - - - EUR 165 598,80 - - - Integrating memories: Exploring knowledge integration enhancement at the intersection of education and neuroscience - - - EUR 165 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Learning about the world is most effective when we can relate new information to previously learned knowledge structures, but underlying neurocognitive processes are still poorly understood. To successfully structure our - knowledge, we can integrate separately learned instances by inferring an association between them. In the brain, this integration of old and new memories has been suggested to be facilitated by the reinstatement of prior knowledge structures during - new learning, but it remains unclear exactly how reinstatement enables effective building of such knowledge structures. Especially in real-world educational settings it is vital to understand how to effectively build knowledge, but thus far direct - translation of neuroscientific insights to educational practice has proven challenging. - - - 2018-11-30, ongoing project - - - 2016-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - Integrating Memories - - - H2020-MSCA-IF-2015 - - - 704506 - - - - - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - - - EUR 2 500 000 - - - Non-sequence models for tokenization replacement - - - EUR 2 500 000 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Natural language processing (NLP) is concerned with computer-based processing of natural language, with applications such as human-machine interfaces and information access. The capabilities of NLP are currently severely - limited compared to humans. NLP has high error rates for languages that differ from English (e.g., languages with higher morphological complexity like Czech) and for text genres that are not well edited (or noisy) and that are of high economic - importance, e.g., social media text. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - NonSequeToR - - - ERC-2016-ADG - - - 740516 - - - - - STICHTING VU - - - EUR 165 598,80 - - - Process Invigoration through Model Embellishment - - - EUR 165 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - The objective of this research project is to enhance business process (BP) model comprehension in European organisations through dynamic process invigoration. Analysis and improvement of BPs are key to organisations’ cost - efficiency and competitiveness. A growing number of organisations in Europe implement BP management solutions to analyse and automate their processes. BP models are invaluable to define, control, improve and communicate BPs. BP models abstract a - dynamic phenomenon in the form of a static representation, thus they are often difficult to comprehend. In this research, I aim at redefining the BP model comprehension problem and developing innovative solutions through a synergetic usage of process - modeling and multimedia disciplines. In this way, models will be dynamically invigorated and presented to business professionals in a comprehensible manner. To fulfil the overall objective, related literature will be reviewed; BP model invigoration - techniques will be designed for eight different embellishment components; the techniques will be evaluated through industrial experiments and field studies; an open source BP model invigoration tool will be developed; and results will be disseminated - in European academy and industry. Eventually, organisations from various domains in Europe can utilize their BP models in a better way by using the freely available PRIME tool to invigorate their processes. This will create an opportunity to increase - organisational efficiency throughout Europe. This project will contribute to my career development in many ways. I will obtain regular training on scientific and transferable skills through interdisciplinary trainings with my supervisor and other - scholars, courses in research schools, and the preparation of publications. Collaboration and networking will be enhanced through joint studies with scholars and industry, enabled by the supervisor’s previous collaborations as well as my experiences. - - 2017-08-31, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - PRIME - - - H2020-MSCA-IF-2014 - - - 660646 - - - - - STICHTING VU - STICHTING VU - - - EUR 1 499 268,75 - - - Peptide-derived bioavailable macrocycles as inhibitors of protein-RNA and protein-protein interactions - - - EUR 1 499 268,75 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The objective of this proposal is the elucidation of general principles for the design of bioavailable peptide-derived macrocyclic compounds and their use for the development of inhibitors of protein‒protein (PPI) and - protein‒RNA interactions (PRI). Over the last decade, drug discovery faced the problem of decreasing success rates which is mainly caused by the fact that numerous novel biological targets are reluctant to classic small molecule modulation. In - particular, that holds true for PPIs and PRIs. Approaches that allow the modulation of these interactions provide access to therapeutic agents targeting crucial biological processes that have been considered undruggable so far. Herein, I propose the - use of irregularly structured peptide binding epitopes as starting point for the design of bioactive macrocycles. In a two-step process high target affinity and bioavailability are installed: - - 2021-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - PEP-PRO-RNA - - - ERC-2015-STG - - - 678623 - - - - - STICHTING VU - STICHTING VU - - - EUR 1 998 655 - - - Social Cognition in Adolescents: Brain Networks and Social Networks - - - EUR 1 998 655 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The forming of social bonds is an evolutionary imperative, and a rich target for empirical research. Social scientists have scrutinized the structure of the elaborate social networks that characterize today’s society. - Neuroscientists have elucidated the brain mechanisms underlying our ability to navigate this social world. Yet, these research lines have been largely separated. This proposal aims to integrate social network research and social brain research, - focusing on adolescence as the most dynamic phase shaping the interplay between social networks and the social brain. Social development in adolescents is clearly driven by maturation of specific social-cognitive functions; yet these functions are - manifest in, and moulded by, interpersonal relationships within social networks. I aim to clarify how changes in the social brain relate to changes in social network position and structure during adolescent development. This can be achieved by using - the quantitative tools of social network analysis in conjunction with the experimental approach of social neuroscience. I plan to investigate a cohort of approximately 1000 adolescents nested in 50 classes in a longitudinal design with 6 measurements - over 3 years; fMRI investigating task-related functional activation and connectivity is conducted yearly in a subsample of 100. The neural and behavioural correlates of social cognition are investigated using experimental tasks tapping i) - understanding others and ii) interacting with others; social behaviour is charted through ecological momentary assessment techniques; social networks are mapped using surveys and digital information acquired routinely via mobile phones (mobile - sensing). This approach clarifies how during a crucial developmental phase the social brain shapes the social environment, and vice versa, the social environment influences maturation of the social brain. - - 2021-01-31, ongoing project - - - 2016-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - SCANS - - - ERC-2014-CoG - - - 648082 - - - - - CHARITE - UNIVERSITAETSMEDIZIN BERLIN - CHARITE - UNIVERSITAETSMEDIZIN BERLIN - - - EUR 1 483 720 - - - Prenatal Stress and Programming of Newborn and Infant Telomere Biology and Cellular Aging - - - EUR 1 483 720 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The long-term consequences of exposure to excess stress on the initiation and progression of many age-related diseases are well established. The period of intrauterine life represents among the most sensitive developmental - windows, at which time the effects of stress may be transmitted inter-generationally from a mother to her as-yet-unborn child. The elucidation of mechanisms underlying such effects is an area of intense interest and investigation. Aging, by - definition, occurs with advancing age, and age-related disorders result from exposures over the life span of factors that produce and accumulate damage. The novel concept advanced in this proposal is that the establishment of the integrity of key - cellular aging-related processes that determine variation across individuals in the onset and progression of age-related disorders may originate very early in life (in utero) and may be plastic and influenced by developmental conditions. We propose - that telomere biology and the epigenetic DNA methylation-based aging profile (DNAmAGE) represent candidate outcomes of particular interest in this context. A prospective, longitudinal cohort study of 350 mother-child dyads will be conducted from - early pregnancy through birth till one year of age. Specific hypotheses about the effects of maternal stress and maternal-placental-fetal stress biology on newborn and infant telomere length, telomerase expression capacity, and DNAmAGE will be - addressed. Serial measures of maternal psychological, behavioral and physiological characteristics will be collected across gestation using an innovative ecological momentary assessment (EMA) based real-time, ambulatory sampling protocol. The - proposed study will help identify new strategies for risk identification and primary and secondary interventions to augment current efforts to prevent, delay and ameliorate age-related disorders. - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - PrenatStressAging - - - ERC-2015-STG - - - 678073 - - - - - STICHTING VU - STICHTING VU - - - EUR 1 500 000 - - - High-resolution microscopy without lenses: a new generation of imaging technology - - - EUR 1 500 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Lensless imaging is an elegant approach to microscopy, in which a sharp image of an object is retrieved by numerical means rather than by actual optical components such as lenses. Such an approach allows high-resolution - imaging using only a light source and an image sensor. Multi-wavelength phase retrieval (Witte et al., patent application PCT/NL2013/050618) provides a general framework for lensless imaging, which allows the development of surprisingly simple yet - high-resolution imaging devices. By detecting wavelength-dependent differences in wave propagation, I have recently shown that amplitude and phase of an object field can be reconstructed with high contrast and resolution. This approach works for - complex objects in both reflection and transmission. As such, lensless microscopes have advantages in size, cost, robustness and simplicity, and provide a powerful alternative to conventional imaging systems in many applications. - - 2020-04-30, ongoing project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - Lensless - - - ERC-2014-STG - - - 637476 - - - - - STICHTING VU - STICHTING VU - - - EUR 1 500 000 - - - THAWing permafrost: the fate of Soil Organic Matter in the aquatic Environment - - - EUR 1 500 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - As the Arctic permafrost region warms, its large organic carbon (OC) pool becomes vulnerable to decomposition. This generates greenhouse gases (GHG) that in turn fuel increased surface warming: the permafrost carbon feedback. - Higher temperatures will jump-start the coupling between the carbon and hydrological cycle, allowing for the introduction of previously frozen OC pools in aquatic systems. This lateral, or horizontal, aquatic flux remains largely unknown in contrast - to the relatively well-studied vertical flux, GHG emission on land. - - - 2021-11-30, ongoing project - - - 2016-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - THAWSOME - - - ERC-2015-STG - - - 676982 - - - - - CHARITE - UNIVERSITAETSMEDIZIN BERLIN - CHARITE - UNIVERSITAETSMEDIZIN BERLIN - - - EUR 1 870 588 - - - Personalized whole brain simulations: linking connectomics and dynamics in the human brain - - - EUR 1 870 588 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Background. We have detailed maps of brain structure and function, yet are lacking understanding of how the highly connected units interact and give rise to mental processes. The Virtual Brain (TVB), a whole brain simulation - framework, aims to bridge that gap. Yet it is still developing. We are proposing here breakthrough advances that reveal mechanisms of brain function and foster collaboration between research groups. Vision. Clinical applications that simulate - individual patient brains and predict trajectories of recovery or decline or test therapies to select the best one for that person. Goal. Using biologically realistic brain models and multimodal functional and structural imaging data to elucidate - control mechanisms of the human brain in aging. A database collects key data and allows identifying most generic models and mechanisms below the spatial and temporal resolution of non-invasive imaging techniques taking into account the complex - interaction in the brain that without a model would be impossible to keep track of. Objectives. 1) Parameter optimization for large parameter space search and a library of dynamical regimes linking dynamical regimes and underlying mechanisms to - biological (cognitive) age. 2) Identifying the role of intrinsic plasticity for network reconfigurations in the resting state and its age dependency. 3) Model based identification of task related plasticity mechanisms and their functional - consequences for network reconfigurations in coordination learning in aging. 4) An interactive tool that provides access to the dynamical regimes library and makes pre-computed simulations easily accessible allowing researchers to benefit and learn - from existing work. Impact. Understanding development, aging and brain disorders from the perspective of disruption of information processing architectures provides an opportunity for new interventions that re-establish control in brain pathology - hence posing a breakthrough in the health and biotech sector. - - 2021-07-31, ongoing project - - - 2016-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - BrainModes - - - ERC-2015-CoG - - - 683049 - - - - - STICHTING VU - STICHTING VU - - - EUR 1 499 482,50 - - - The Human Behavioral Immune System: Consequences for Health and Innovation - - - EUR 1 499 482,50 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Modern innovations such as soap, condoms, and indoor plumbing have allowed billions of people to reduce their contact with viruses and bacteria and, as a result, dramatically increase length and quality of life. But how did - members of the genus homo avoid pathogens for the two million years that preceded these technological innovations and, more broadly, discoveries that infectious disease is caused by microbes? And, importantly, how do any natural behavioral defenses - against pathogens impact our behavior in the modern world? Recent research and theory in the field of evolutionary psychology suggests that natural selection has shaped a human behavioral immune system (HBIS)—a suite of psychological mechanisms, - ranging from aspects of our olfactory systems (e.g., that detect specific chemical compounds) to our emotion systems (e.g., the emotion disgust) and our learning systems (e.g., conditioned aversions to foods) that are coordinated for a common - function: to detect and motivate the avoidance of pathogens. Given that myriad universal human behaviors connote some pathogen risk—including interpersonal contact, mating, and eating—gaining a holistic understanding of the HBIS has the potential to - offer critical new insights into multiple fundamental aspects of human nature. Here, I utilize an interdisciplinary approach to answer three foundational, yet currently opaque questions concerning the nature of the HBIS, including: (1) Where does - trait variation in HBIS activation come from? (2) What effect does the HBIS have on behavior when cues to pathogens are detected? and (3) How does the HBIS facilitate learning of avoidance and rejection? To answer these questions, I propose an array - of methodologically diverse studies to investigate how trait HBIS activation shapes rejection versus acceptance of innovations, how state HBIS activation can be harnessed to promote the use of health-promoting technologies, and how the HBIS can be - leveraged for shaping dietary behavior. - - 2021-06-30, ongoing project - - - 2016-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - HBIS - - - ERC-2015-STG - - - 680002 - - - - - STICHTING VU - - - EUR 167 610,60 - - - Beta-cell inflammation and dysfunction induced by bacterial translocation - - - EUR 167 610,60 - - - Netherlands - - - Higher or Secondary Education Establishments - - Type 2 diabetes (T2D) has risen to epidemic proportions resulting in major morbidity and mortality. In addition to insulin resistance (i.e. impaired insulin action), impaired function and destruction of the insulin-producing - beta cells form the direct cause for hyperglycemia and T2D, and causes the progressive course of disease. As such, due to continuous beta-cell destruction, many patients require treatment with exogenous insulin therapy. Clearly, therapies that may - halt or reverse this detrimental process are warranted. - - 2018-05-31, ongoing project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Netherlands - - - BETA-BACT - - - H2020-MSCA-IF-2015 - - - 708193 - - - - - STICHTING VU - STICHTING VU - - - EUR 1 500 000 - - - Releasing Prisoners Of The Paradigm: Understanding How Cooperation Varies Across Contexts In The Lab And Field - - - EUR 1 500 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Cooperation is essential for mitigating conflict between individual and collective interests in relationships and groups, such as providing public goods and conserving resources. Most research testing psychological and - economic theory of cooperation has applied a highly specific lab method (e.g., the prisoner’s dilemma) that unnecessarily constrains the applicability of research findings. The discrepancies between cooperation observed in the lab and field can be - due to variation in interdependence. Two limitations of lab studies to generalizing findings to the field are that (1) lab studies contain interdependence that differs from reality and (2) in the field people lack knowledge about their objective - interdependence with others – and must infer their interdependence. I propose two inter-related research programs that test hypotheses derived from Functional Interdependence Theory on how objective and perceived interdependence affect cooperation. - Project 1 applies meta-analysis to test hypotheses about how variation in objective interdependence across lab studies moderates the effectiveness of strategies to promote cooperation. Because Project 2 involves a pioneering effort to catalogue and - analyze the 60 year history of research on cooperation, I will apply these efforts to develop an international, multidisciplinary institution and open access database for cataloguing studies in a way that facilitates scientific progress. Project 2 - (a) develops a measure of perceived interdependence, (b) observes the interdependence people encounter in their daily lives, (c) tests two models of how people think about interdependence, and (d) innovates and applies a method to test hypotheses - about factors that influence accuracy and bias in perceptions of interdependence. To maximize the ecological validity of research findings, I study cooperation in different samples (students, romantic couples, and employees) with the use of multiple - methods (survey, experimental, and field). - - 2020-07-31, ongoing project - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - COOPERATION - - - ERC-2014-STG - - - 635356 - - - - - CHARITE - UNIVERSITAETSMEDIZIN BERLIN - - - EUR 171 460,80 - - - Intentions in Action: Establishing the neural causes of intentional action - - - EUR 171 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - The neuroscientific study of intentional action has produced puzzling and contradictory results: intentions show up at a variety of brain locations, and up to ten seconds before a decision has been made. Recently, it has been - argued that intentions do not underlie voluntary action at all. At the same time neural states have been found that could be correlated with future actions, suggesting a role for intentions after all. The proposed project suggests that the cause of - these seemingly contrasting results lies in the heterogeneous composition of everyday actions, consisting of both immediate and future-directed components. The proposed research promises to go to the bottom of this controversy by investigation what - types of actions can be accomplished without discrete states like intentions, and for what types of actions intentions are needed. It will do so by looking for common factors in brain states underlying actions using functional Magnetic Resonance - Imaging. Particularly, it will be investigated whether similarity in motor acts, actions, or contexts are crucial for finding commonalities in brain states. - - - 2017-07-31, closed project - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - Intentions in Action - - - H2020-MSCA-IF-2014 - - - 657605 - - - - - STICHTING VU - STICHTING VU - - - EUR 2 497 664 - - - The Proton Size Puzzle: Testing QED at Extreme Wavelengths - - - EUR 2 497 664 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - A key component of the Standard Model is Quantum Electrodynamics (QED). QED explains e.g. the anomalous magnetic moment of the electron and small energy shifts in the energy structure of atoms and molecules due to vacuum - fluctuations. After decades of precision measurements, especially laser spectroscopy in atomic hydrogen, QED is considered the most successful and best-tested theory in physics. However, in 2010 precision spectroscopy in muonic-hydrogen (where the - electron is replaced with a muon) has lead to discrepancies in energy level structure that cannot be accounted for. If QED is considered correct, then one way of interpreting the results is that the size of the proton is different in normal - (electronic) hydrogen by as much as 4% (a 7 sigma effect) compared to muonic hydrogen. Despite great theoretical and experimental efforts, this 'proton size puzzle' is still unsolved. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Netherlands - - - QED-PROTONSIZE - - - ERC-2015-AdG - - - 695677 - - - - - STICHTING VU - DANMARKS TEKNISKE UNIVERSITET - KOBENHAVNS UNIVERSITET - UNIVERSITY COLLEGE LONDON - LUMICKS B.V. - - - EUR 3 567 025 - - - Super-resolution visualisation and manipulation of metaphase chromosomes - - - EUR 3 567 025 - - - Netherlands - Denmark - Denmark - United Kingdom - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - CHROMAVISION aims to develop a pioneering chromosome imaging and manipulation platform that will fuel the next decades of structural chromosome research. Chromosomal abnormalities are characteristic of many disorders such as - cancer, impaired fertility due to maternal aging, and neurological disorders such as fragile X syndrome. If humanity is to fully understand the wide range of diseases that are associated to errors in cell division, we must be able to further 'zoom - in' on healthy and diseased chromosomes in all their complexity. The CHROMAVISION platform will allow molecular biologists to automatically isolate individual chromosomes from small tissue or cell samples and have these delivered to a - super-resolution microscope. Chromosome isolation and delivery is achieved by an opto-fluidic chip that is able to trap, visualise and lyse individual cells and separate metaphase chromosomes from cell lysate. Single chromosomes can be - “hand-selected” and brought into focus of the Super-Resolution Correlative Tweezers Fluorescence Microscope (CTFM-SR3D) that is developed in CHROMAVISION. This instrument will for the first time enable 3D, super-resolution, real-time metaphase - chromosome observation and manipulation studies under near-physiological conditions. The technique will push the boundaries of what is currently possible in microfluidics and super-resolution microscopy and combine these into a single powerful - approach for chromosome studies. Furthermore, the platform will be applied in CHROMAVISION to address key challenges in clinical and fundamental chromosome research, potentially resulting in breakthrough discoveries. Better imaging and understanding - of the chromosomal mechanisms will contribute to our knowledge of the etiology of human diseases and aid drug discovery. The platform will also have large clinical value, allowing identification and monitoring of e.g. cancer heterogeneity. - - 2019-05-31, ongoing project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-1-2014 - FET-Open research projects - - - RIA - Research and Innovation action - - - Netherlands - - - CHROMAVISION - - - H2020-FETOPEN-2014-2015-RIA - - - 665233 - - - - - STICHTING VU - STICHTING VU - - - EUR 147 500 - - - Imaging with Photon Counting: Reduced costs, increased dynamic range - - - EUR 147 500 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Optical methods and fluorescent proteins to probe and manipulate cellular and subcellular processes have proven to be a major driving force behind many recent breakthroughs in biology and medicine. Recent developments in - photonics have led to increased spatial and temporal resolution and now allow the study of single identified synaptic contacts between neurons as well as large-scale neuronal networks. Brain tissue strongly scatters light. Thereby, the amount of - light emitted by fluorescent probes in small structures inside neuronal tissue that reaches the microscope objective is small. Fluorescence imaging in living tissue, as I use in my ERC-funded research program, is therefore limited by low - signal-to-noise levels. One approach in increasing the level of such weak fluorescence is to increase the excitation power, but this has the undesirable effect of bleaching the fluorescence faster and damaging the cell. Another approach is to - optimize the fluorescence collection by using high-end microscope objectives in the 20,000 eur range with improved light transmission, high numerical aperture and low magnification that can collect fluorescence more efficiently. Although these - objectives brought a significant improvement to imaging applications, physical limitations in their design cannot offer anymore a similar qualitative improvement as previously. Since there is a great need to further improve biological imaging, the - present proof of concept application aims to achieve this by developing advanced, but low-cost, electronics for the optical detection of weak fluorescence signals through Photon Counting, and bring this technology to the market. - - 2016-03-31, closed project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2014 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Netherlands - - - PhotonCount - - - ERC-2014-PoC - - - 665522 - - - - - STICHTING VU - STICHTING VU - - - EUR 150 000 - - - Launching Acoustic Force Spectroscopy - unlocking the potential of biomolecular bungee jumping - - - EUR 150 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - ACOFORS has been designed with the ultimate goal of preparing commercialisation of Acoustic Force Spectroscopy (AFS). AFS is a completely new and powerful technique for determining biomolecular mechanics and structure of - single molecules such as DNA and proteins. These studies are performed on a large scale by biologists and within pharmaceutical companies for e.g. drug discovery and development. Current technologies for force spectroscopy (FS) represent a $50+ - million market, but are expensive, require high levels of specialism and are laborious. AFS, invented in the laboratory of Prof. Wuite, is much simpler to use, can be operated in high-throughput mode and can become available at relative low cost. As - such, AFS vastly expands the possibilities of FS and makes it available to a much wider community. This makes AFS a very attractive technology for science and business, both from the perspective of the user and of the seller. - - - 2016-06-30, closed project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2014 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Netherlands - - - ACOFORS - - - ERC-2014-PoC - - - 665656 - - - - - STICHTING VU - - - EUR 165 598,80 - - - Quantum coherence in photosynthesis: towards single-molecule light-conversion devices - - - EUR 165 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Photosynthesis performed by plants, algae and photosynthetic bacteria is the biological process that transforms solar energy into chemical energy with high quantum efficiency. A complete understanding of the factors that - modulate the efficiency of this process is a challenge centered at the nexus of fundamental physics and biology, and obtaining that knowledge could pave the way for the design of the next generation of cheap and highly-efficient light-conversion - devices. The main aim of this project is to understand how quantum coherence modulates the efficiency of photosynthesis. Quantum coherence is likely to be involved in not only the first ultrafast stages of excitation energy transfer in the - photosynthetic light harvesting antenna but also in the charge separation process in the photosynthetic reaction center by coupling to specific vibrational states of this pigment-protein complex (Romero et al, Nature Physics 10, 676-682, 2014). Here - we propose to use time-resolved coherent anti-Stokes Raman spectroscopy and two-dimensional photon echo spectroscopy to demonstrate the specific vibrational modes that sustain quantum coherence at the single molecule level. Time-resolved anti-Stokes - Raman spectroscopy will provide an insight into the specific vibrations in the molecule that lead to sustained quantum coherence in the charge separation steps of photosynthesis. Results will be confirmed using two-dimensional photon echo - spectroscopy and rationalized in a Redfield theory framework. To assess the role of energetic disorder, reaction centers will also be characterized using a combination of single-molecule techniques in order to correlate the quantum coherence arising - at the single-molecule level with the efficiency of the whole ensemble. To achieve this, a new technique capable of quantifying quantum coherence at the nanoscale will be developed. This new technique and its applications will deeply impact quantum - biology and other fields. - - 2017-09-30, closed project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - QuantumPhotosynth - - - H2020-MSCA-IF-2014 - - - 660521 - - - - - STICHTING VU - - - EUR 177 598,80 - - - The travelling astronomers. International collaborations after World War II and the reorganization of European astronomy (1953-1985) - - - EUR 177 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - This research project investigates the history of astronomy in Europe after World War II. In the period between 1953 and 1985, a number of international collaborations were undertaken by several European countries, with the - aim of strengthening astronomical research in terms of its capacity and facilities. These collaborations culminated in the construction of powerful observational facilities and the implementation of programmes for cooperation in professional - research. In this respect, the initiatives taken from 1953 to 1985 inaugurated a new era of European astronomy. Indeed, in this period research facilities were made available in both hemispheres, new research networks were created, and there was a - new attitude towards scientific cooperation. - - 2017-05-31, closed project | - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - ISHTAR - - - H2020-MSCA-IF-2014 - - - 656139 - - - - - STICHTING VU - - - EUR 165 598,80 - - - Urban networks: multidisciplinary research into the formation of early urban societies in Campania (Italy) - - - EUR 165 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Living in cities has been one of the most transformative innovations in human history: it has heavily impacted social and political interaction between people, and has significantly changed the relationship between man and his - natural environment. Understanding why people in the past started living together in cities in the first place, provides crucial tools for the study of urban life from a comparative perspective. - - 2018-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - URBANet - - - H2020-MSCA-IF-2015 - - - 702511 - - - - - AKVAPLAN-NIVA AS - - - EUR 196 400,40 - - - Biological Impact of Oil Pollution in Arctic and Deep-sea Environment - - - EUR 196 400,40 - - - Norway - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - "The increase demand of oil, associated with the depletion of easily exploitable oil deposits is leading the oil industry to intensify the search for new oil areas and exploit deposits previously considered as economically - unprofitable. These new oil research areas are mostly located in Arctic waters and in the "offshore" areas in deep waters. However, very few studies have investigated the biological impacts of oil contamination in these very specific areas. - Practically, the research actions will estimate the potential synergistic effect of oil, warming and hypoxia on a key Arctic species, polar cod Boreogadus saida (Work package 1, WP1).The project will then will focus on the impacts of the soluble - fraction of oil on the metabolism of deep benthic species, in particular Lophelia pertusa and Eurythenes gryllus (WP 2). WP3 will consist of an applied study in order to validate two experimental set-ups which could make possible the assessment of - the impact of oil in deep-sea environments. Finally, WP4 will be devoted to provide recommendations to perform a relevant NEBA in Arctic and deep-sea areas. The complementarities between the applicant and the supervisors profiles, associated with - partner organizations skills ensure the realization of this innovative project and the dissemination and exploitation of the different results." - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-SE - Society and Enterprise panel - - - Norway - - - BIOPADE - - - H2020-MSCA-IF-2016 - - - 750511 - - - - - STICHTING VU - STICHTING VU - - - EUR 2 500 000 - - - Probing Physics beyond the Standard Model from Molecules - - - EUR 2 500 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The Standard Model of physics is incomplete. Gravity is not understood at the quantum level, dark matter and dark energy are not explained, and (string)-theories searching to cover these shortcomings are only consistent in - higher-dimensional spaces, while only four of those dimensions are observed. The mystery of finely tuned strengths of the fundamental forces, providing us with a Universe of complexity, remains unexplained. This calls for new physics that can also be - explored at the atomic scale in the low energy domain. That is the paradigm underlying the present proposal: Effects of new physics – either related to hitherto unknown particles or to symmetry-breaking phenomena – will manifest themselves as minute - shifts in the quantum level structures of atoms and molecules, in minute drifts over time or dependencies on environmental conditions. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Netherlands - - - NEWPHYS-MOLECULES - - - ERC-2014-ADG - - - 670168 - - - - - STICHTING VU - STICHTING VU - - - EUR 150 000 - - - Development of an Anger Regulation Tool for Hand-Held Devices - - - EUR 150 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Our research team at the Amsterdam Emotion regulation Lab (emotionregulationlab.com) has recently established that avoidance movements can lower anger and aggression among individuals with chronic anger management problems. - Building on and extending these findings, we propose to develop, test, and market an interactive application that runs on mobile devices such as smart phones and tablets. This Anger Reduction Tool (ART) will consist of a ‘serious game’ that trains - people to make avoidance movements to angry faces. The ART will be commercialized through a freemium model, such that it will be made freely available, while users can purchase additional functionalities using bio- and neuro-feedback modules. The ART - will be marketed to mental health professionals with clients who are not willing or able to respond to traditional cognitive interventions, such as high school children or lower-educated violent offenders. By harnessing the possibilities of smart - technology, the ART allows people to become co-managers of their (mental) health and well-being. - - 2018-06-30, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2015 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Netherlands - - - ART - - - ERC-2015-PoC - - - 693623 - - - - - STICHTING VU - STICHTING VU - - - EUR 1 962 679 - - - It’s not my fault I am aggressive, they picked on me: How early peer relations affect DNA methylation and neurocognitive development in children - - - EUR 1 962 679 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Think about the day you took your child to kindergarten for the first time. You were worried. Worried about the social experiences of your child. Would peers like your child, or would it get bullied, or rejected by classmates? - - - 2020-06-30, ongoing project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - socio-bio interplay - - - ERC-2014-CoG - - - 646594 - - - - - STICHTING VU - STICHTING VU - - - EUR 1 870 135 - - - The molecular genetic architecture of educational attainment and its significance for cognitive health - - - EUR 1 870 135 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Since many social and economic outcomes are moderately heritable, it is in principle possible to discover genetic variants associated with them. Such discoveries could yield new insights into the causal pathways underlying - human behaviour, the complex interplay of environmental and genetic factors, and the relationship between socio-economic traits and health. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - EdGe - - - ERC-2014-CoG - - - 647648 - - - - - INSTITUTO SUPERIOR TECNICO - - - EUR 100 397,25 - - - Action understanding in human and robot dyadic interaction - - - EUR 100 397,25 - - - Portugal - - - Higher or Secondary Education Establishments - - Humans have fascinating skills for grasping and manipulation of objects, even in complex, dynamic environments, and execute coordinated movements of the head, eyes, arms, and hands, in order to accomplish everyday tasks. When - working on a shared space, during dyadic interaction tasks, humans engage in non-verbal communication, by understanding and anticipating the actions of working partners, and coupling their actions in a meaningful way. - - - 2018-08-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Portugal - - - ACTICIPATE - - - H2020-MSCA-IF-2016 - - - 752611 - - - - - UNIVERSITEIT VAN AMSTERDAM - - - EUR 165 598,80 - - - Ecological and Evolutionary consequences of predator-prey phenological match-mismatch driven by climate change - - - EUR 165 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Global Climate Change (CC) is affecting the phenotype, abundance, and distribution of animal and plant populations as well as their interactions, e.g. phenological shifts affecting predator-prey time match-mismatch. - Understanding how organisms cope with change is a fundamental objective of biologists. Scientists are now increasingly aware that ecological and evolutionary change in response to CC can occur concurrently, while their interaction can affect - populations in a process called eco-evolutionary dynamics. However, we know little about the role of genetic and correlated traits variation and their relations to plasticity in the ability of organisms to cope with CC. The main goal of EcoEvoClim is - to assess the role of genetic variation and plasticity in the eco-evolutionary response to CC of (mis)timed predator populations with a genetically determined colour polymorphism that covaries with behavioural traits. To this aim, I will use - observational and theoretical approaches, by combining state-of-the art technology (fine-resolution GPS telemetry and bird migration radar), long-term field datasets, and latest population modelling tools (Integral Projection Models). This - challenging goal will be achieved by joining a research group where world renowned experts at the forefront of developing and applying these techniques and concepts proposed here will collaborate to develop this project. EcoEvoClim, at the interface - of behavioural ecology and evolutionary biology, will follow a multidisciplinary approach, synthetizing concepts from the fields of movement ecology, meteorology, remote sensing, genetics and population dynamics. The Fellowship will provide me with a - unique opportunity to deepen my knowledge on eco-evolutionary research, as well as expertise in the use of modern technology for field research and analytical tools that integrate population ecology, life history theory and evolution to evaluate the - likelihood of persistence of populations facing CC. - - 2019-05-14, ongoing project - - - 2017-05-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - EcoEvoClim - - - H2020-MSCA-IF-2016 - - - 747729 - - - - - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - - - EUR 164 653,20 - - - Quantum Enhanced Sensing with Cold Atoms - - - EUR 164 653,20 - - - Greece - - - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - - Atom sensors based on cold atoms have demonstrated great potential in precision measurements both in applied technology and in fundamental science. The main limitation is now the quantum projection noise originating from the - counting of uncorrelated atoms. This limit can only be broken by entangling the probe atoms and creating squeezed states. We propose a novel scheme for generating squeezing in ultra-cold atomic ensembles via quantum-non-demolition measurements based - on the cavity-aided measurement of the Faraday optical rotation that light experiences as it travels through the atomic medium. This method holds the promise of realizing a significant squeezing with a medium-finesse optical cavity without the use of - additional optical interferometers. It outperforms conventional detection schemes based on absorption imaging by allowing smaller dead time between consecutive measurements. Applications include atomic clocks and inertial sensors, which can be used - for technical applications (gravitational geodesy, gravimetry for oil, gas and rare metal exploration and cavity detection in construction) and for fundamental physics experiments (gravitational wave detectors, Einstein Equivalence test and - gravitational tests of the standard model). - - 2019-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Greece - - - QUESCA - - - H2020-MSCA-IF-2016 - - - 750017 - - - - - STICHTING VU - STICHTING VU - - - EUR 1 999 891,25 - - - Improving the accuracy and reliability of electronic structure calculations: New exchange-correlation functionals from a rigorous expansion at infinite coupling strength - - - EUR 1 999 891,25 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - By virtue of its computational efficiency, Kohn-Sham (KS) density functional theory (DFT) is the method of choice for the electronic structure calculations in computational chemistry and solid-state physics. Despite its - enormous successes, KS DFT’s predictive power and overall usefulness are still hampered by inadequate approximations for near-degenerate and strongly-correlated systems. Crucial examples are transition metal complexes (key for catalysis), stretched - chemical bonds (key to predict chemical reactions), technologically advanced functional materials, and manmade nanostructures. - - - 2020-07-31, ongoing project - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - corr-DFT - - - ERC-2014-CoG - - - 648932 - - - - - STICHTING VU - - - EUR 418 560 - - - Scientific Top Training in Antimicrobial Research - - - EUR 837 120 - - - Netherlands - - - Higher or Secondary Education Establishments - - The Amsterdam Institute for Molecules, Medicines and Systems (AIMMS, www.aimms.vu.nl) offers an innovative selection procedure for international Top Master's Students to train a new generation of top scientists who can - contribute to solving the problem of bacterial, viral and parasitic diseases. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2015-DP - Marie Skłodowska-Curie Co-funding of regional, national and international programmes (COFUND-DP) - - - MSCA-COFUND-DP - Doctoral programmes - - - Netherlands - - - AIMMS STAR-PLUS - - - H2020-MSCA-COFUND-2015 - - - 713669 - - - - - STICHTING VU - STICHTING VU - - - EUR 1 331 625 - - - Brain meets spine: the neural origin of toddler’s first steps - - - EUR 1 331 625 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - A child’s first steps may be small, but they are a giant leap for its development. Children have an instinct to walk from the moment they are born – a 'stepping reflex' hardwired in their neural circuitry – but it typically - takes about one year before they can start walking independently. In a pioneering work published on Science in 2011, I demonstrated that the coordinated muscle activation in neonate stepping is described by two basic activation patterns that are - retained throughout development, and supplemented by two new ones that be-come manifest in toddlers. - - 2022-01-31, ongoing project - - - 2017-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - Learn2Walk - - - ERC-2016-STG - - - 715945 - - - - - STICHTING VU - STICHTING VU - - - EUR 1 597 291 - - - Proving or improving yourself: longitudinal effects of ability beliefs on neural feedback processing and school outcomes - - - EUR 1 597 291 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - To successfully complete secondary education, persistent learning behavior is essential. Why are some adolescents more resilient to setbacks at school than others? In addition to actual ability, students’ implicit beliefs - about the nature of their abilities have major impact on their motivation and achievements. Ability beliefs range from viewing abilities as “entities” that cannot be improved much by effort (entity beliefs), to believing that they are incremental - with effort and time (incremental beliefs). Importantly, ability beliefs shape which goals a student pursues at school; proving themselves (performance goals) or improving themselves (learning goals). The central aims of the proposal are to unravel - 1) the underlying processing mechanisms of how beliefs and goals shape resilience to setbacks at school and 2) how to influence these mechanisms to stimulate persistent learning behavior. - - 2022-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - BRAINBELIEFS - - - ERC-2016-STG - - - 716736 - - - - - THE UNIVERSITY OF BIRMINGHAM - UNIVERSITEIT ANTWERPEN - UNIVERSITY OF BATH - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - UNIVERSITAT ROVIRA I VIRGILI - STICHTING VU - STOCKHOLMS UNIVERSITET - Masarykova univerzita - STIFTELSEN NORGES GEOTEKNISKE INSTITUTT - SUEZ VYUZITI ZDROJU AS - - - EUR 832 500 - - - Synergising International Research Studies into the Environmental Fate and Behaviour of Toxic Organic Chemicals in the Waste Stream - - - EUR 1 008 000 - - - United Kingdom - Belgium - United Kingdom - Spain - Spain - Netherlands - Sweden - Czech Republic - Norway - Czech Republic - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The overall vision of INTERWASTE is to develop scientific understanding of issues related to environmental contamination with toxic organic chemicals (specifically flame retardants (FRs) and pharmaceutical and personal care - products (PPCPs)) arising from their presence in the waste stream. Specific research objectives include: (a) exchange of knowledge of and best practice in methods for rapid and cost-effective identification of waste items containing restricted FRs; - (b) developing scientific understanding of environmental contamination due to processing of waste items containing FRs; and (c) furthering understanding of the sources of PPCPs and FRs in the sewerage system. To facilitate such research on the global - level required, INTERWASTE will exchange best practice in the analytical chemistry techniques required to study FRs and PPCPs, and evaluate the measurement capability of INTERWASTE participants via an interlaboratory comparison. INTERWASTE's vision - will be achieved via a co-ordinated programme of collaboration and research secondments between world-leading research groups both within and outside the EU; coupled with annual workshops to discuss the latest findings. The research programme will - exploit the complementary expertise of the consortium members, and in so doing foster synergies. Cross-sectoral interaction and knowledge sharing will be achieved via the participation of beneficiaries and partner organisations from both academic and - non-academic sectors. All secondments and workshops will be conducted within a framework designed to maximise the training and career development benefits to participating staff by providing them with opportunities for knowledge and skills - acquisition, with a particular (but not exclusive) focus on early career researchers. INTERWASTE's research and training programme is complemented by communication activities that will both disseminate project findings to scientific stakeholders, and - engage the general public. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - United Kingdom - - - INTERWASTE - - - H2020-MSCA-RISE-2016 - - - 734522 - - - - - THE UNIVERSITY OF WARWICK - - - EUR 195 454,80 - - - Explicit Methods for the Darmon Programme - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Elliptic curves are the heart of contemporary research in number theory. For example, their modularity played a crucial role in Wiles' proof of Fermat's Last Theorem. Understanding their rational points is the subject of the - Birch and Swinnerton-Dyer Conjecture (BSD), one of the seven $1M Clay Mathematics Institute Millennium Prizes. This proposal is concerned with rational points on elliptic curves and linked to both BSD and modularity. - - 2017-08-31, Grant Agreement terminated | - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ExplicitDarmonProg - - - H2020-MSCA-IF-2014 - - - 655662 - - - - - THE UNIVERSITY OF LIVERPOOL - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH - CIVIDEC INSTRUMENTATION GMBH - COSYLAB LABORATORIJ ZA KONTROLNE SISTEME DD - FOTON SRO - GSI HELMHOLTZZENTRUM FUER SCHWERIONENFORSCHUNG Gmbh - FORSCHUNGSZENTRUM JULICH GMBH - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN - STAHL STEFAN - THE UNIVERSITY OF MANCHESTER - - - EUR 3 848 975,64 - - - Accelerators Validating Antimatter physics - - - EUR 3 848 975,64 - - - United Kingdom - Switzerland - Austria - Slovenia - Czech Republic - Germany - Germany - Germany - Austria - Germany - United Kingdom - - - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - Antiprotons, stored and cooled at low energies in a storage ring or at rest in traps, are highly desirable for the investigation of basic questions on fundamental interactions, the static structure of antiprotonic atoms, CPT - tests by high-resolution spectroscopy on antihydrogen, as well as gravity experiments. Antimatter experiments are at the cutting edge of science. They are, however, very difficult to realize and have been limited by the performance of the only - existing facility in the world, the Antiproton Decelerator (AD) at CERN. The Extra Low Energy Antiproton ring (ELENA) will be a critical upgrade to this unique facility and commissioned from summer 2016. This will significantly enhance the beam - quality and enable new experiments. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - AVA - - - H2020-MSCA-ITN-2016 - - - 721559 - - - - - ECOLE SUPERIEURE DE PHYSIQUE ET DECHIMIE INDUSTRIELLES DE LA VILLE DEPARIS - FONDATION PIERRE-GILLES DE GENNES POUR LA RECHERCHE - KUNGLIGA TEKNISKA HOEGSKOLAN - TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY - RTD TALOS LIMITED - - - EUR 3 027 637,50 - - - Fabricating colloidal materials with microfluidics - - - EUR 3 027 637,50 - - - France - France - Sweden - Israel - Cyprus - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - In the field of colloidal science, much progress has been done on the synthesis of complex building blocks mimicking molecular structures with the hope of elaborating innovative materials. However, in the present state of the - art, the rates at which these building blocks are obtained are exceedingly small. As a consequence, even though theoretically, revolutionary materials can be imagined, throughputs are far too low to approach industrial applications. We propose to - unlock this bottleneck with microfluidic technology. - - - 2019-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-1-2014 - FET-Open research projects - - - RIA - Research and Innovation action - - - France - - - Microflusa - - - H2020-FETOPEN-2014-2015-RIA - - - 664823 - - - - - THE UNIVERSITY OF NOTTINGHAM - UNIVERSITEIT MAASTRICHT - KAROLINSKA INSTITUTET - UNIVERSITY COLLEGE LONDON - VRIJE UNIVERSITEIT BRUSSEL - UNIVERZITA KARLOVA - STICHTING VU - I MAS D Y EMPLEO SERVICONSULTING SL - STICHTING VUMC - - - EUR 3 878 757 - - - Interdisciplinary Network for Dementia Utilising Current Technology (INDUCT) - - - EUR 3 878 757 - - - United Kingdom - Netherlands - Sweden - United Kingdom - Belgium - Czech Republic - Netherlands - Spain - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - Dementia raises complex challenges for people with dementia, their families, and society. The European Parliament has called for investment in high quality, innovative technology research to improve dementia care but so far - there has been little benefit because research has generally been limited, small scale and methodologically flawed. In particular: the poor understanding between research and business of how people with dementia use technology means new applications - are designed without an in-depth appreciation of people’s needs, preferences and limitations; there is little knowledge about practical, psychological and social barriers and facilitators to implementation making it hard to get results into practice; - there is a serious shortage of research trained professionals who combine expertise on dementia care research and technology. In conjunction with INTERDEM the world’s largest network of psychosocial research for people with dementia this ITN will: - develop a European multi-disciplinary, intersectoral educational research framework for Europe, to comprehensively train 15 early stage researchers (ESRs) to PhD level; provide the research evidence to show how technology may improve care and quality - of life for people with dementia; and provide the European workforce with a much needed new generation of excellent research trained professionals. The objectives of INDUCT are to: determine practical, cognitive & social factors to improve - usability of technology; evaluate the effectiveness of specific contemporary technology; trace facilitators & barriers for implementation of technology in dementia care. Using advanced methods in applied health research (e.g. randomised - controlled trials, qualitative studies) INDUCT will provide the evidence needed to demonstrate how to make dementia care technology more usable, more effective, and better implemented in practice, culminating in an international consensus guideline - for improving policy and practice. - - 2020-02-29, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - INDUCT - - - H2020-MSCA-ITN-2015 - - - 676265 - - - - - FORSCHUNGSZENTRUM JULICH GMBH - INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE - BIOTECHNOLOGY AND BIOLOGICAL SCIENCES RESEARCH COUNCIL - VIB - CONSIGLIO NAZIONALE DELLE RICERCHE - THE UNIVERSITY OF NOTTINGHAM - STICHTING WAGENINGEN RESEARCH - UNIVERSITE CATHOLIQUE DE LOUVAIN - - - EUR 4 000 000 - - - Preparation for EMPHASIS: European Infrastructure for multi-scale Plant Phenomics and Simulation for food security in a changing climate - - - EUR 4 000 000 - - - Germany - France - United Kingdom - Belgium - Italy - United Kingdom - Netherlands - Belgium - - - Research Organisations - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - - Sustainable food security and increasing availability of plant biomass for human nutrition and bioindustries is the key challenge for the coming decades. The analysis of crop performance with respect to structure, function, - quality and interaction with the environment (“phenotyping”) remains the bottleneck for the exploitation of crop genetic diversity required for the enhancement of plant productivity and progress in plant breeding. This requires substantial and - concerted action to develop and to increase the availability of phenotyping infrastructures. The European Strategic Forum for Research Infrastructure (ESFRI) has identified “Plant Phenotyping” as a priority for the European research area and EMPHASIS - has been listed on the ESFRI ROADMAP as an infrastructure project to develop and implement a pan-European plant phenotyping infrastructure. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-02-2016 - Preparatory Phase and support to early phase of ESFRI projects - - - CSA - Coordination and support action - - - Germany - - - EMPHASIS-PREP - - - H2020-INFRADEV-2016-2 - - - 739514 - - - - - UNIVERSITAT WIEN - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - THE UNIVERSITY OF EDINBURGH - INSTITUT JOZEF STEFAN - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - ECOLE SUPERIEURE DE PHYSIQUE ET DECHIMIE INDUSTRIELLES DE LA VILLE DEPARIS - UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA - UNILEVER U.K. CENTRAL RESOURCES LIMITED - Rhodia Laboratoire du Futur - - - EUR 3 895 886,88 - - - Hybrid Colloidal Systems with Designed Response - - - EUR 3 895 886,88 - - - Austria - United Kingdom - United Kingdom - Slovenia - Greece - France - Italy - United Kingdom - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The etymology of the word colloid stems from the Greek word for glue. The systematic study of colloids (as we perceive them nowadays) is considered to have begun in the middle of the 19th century. However, the word colloid - itself had been mentioned before in very different senses. The development of the physics and chemistry of colloids really took off in the 20th century. Colloids found different applications in almost every part of our lives, and it might even seem - that these systems are fully understood and “tamed”. In reality, this is far from the case! Both fundamental understanding and a clear application strategy are required. This is most evident when it comes to the relationship between the nature and - arrangement of the colloidal particles and their macroscopic response to an external field (be that shear, electric, magnetic or gravitational fields). To elucidate this relationship we unite 7 academic and 2 industrial partners and 5 associate - partners to train 15 ESRs. We aim to develop the concept of COLLoids with DEsigned respoNSE, leading to our acronym: COLLDENSE. Scientific projects are divided into three main workpackeges according to the complexity of the building blocks: - deformable colloids, hybrid colloids and colloidal mixtures. The subjects vary from soft repulsive colloids, magnetic colloids, soft microgel particles, telechelic star polymers to droplets with interfaces stabilised by solid particles and DNA - nano-constructs. The detailed analysis of mixtures of these components, as well as of their equilibrium and nonequilibrium thermodynamics and rheology, is the other important facet of the project. In order to obtain a complete understanding of the - colloidal behaviour under an external drive we employ the three main tools of the modern natural science: experiment, computer simulations and analytical theory. This complete approach will also yield a broad training experience for the young members - of the network. - - 2018-12-31, ongoing project | - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Austria - - - COLLDENSE - - - H2020-MSCA-ITN-2014 - - - 642774 - - - - - LEIBNIZ-INSTITUT FUR ASTROPHYSIK POTSDAM (AIP) - LEIBNIZ-INSTITUT FUR ASTROPHYSIK POTSDAM (AIP) - HITS GGMBH - - - EUR 2 000 000 - - - The Impact of Cosmic Rays on Galaxy and Cluster Formation - - - EUR 2 000 000 - - - Germany - Germany - Germany - - - Research Organisations - Research Organisations - Research Organisations - - "Understanding the physics of galaxy formation is arguably among the greatest problems in modern astrophysics. Recent cosmological simulations have demonstrated that ""feedback"" by star formation, supernovae and active - galactic nuclei appears to be critical in obtaining realistic disk galaxies, to slow down star formation to the small observed rates, to move gas and metals out of galaxies into the intergalactic medium, and to balance radiative cooling of the - low-entropy gas at the centers of galaxy clusters. This progress still has the caveat that ""feedback"" was modeled empirically and involved tuning to observed global relations, substantially weakening the predictive power of hydrodynamic - simulations. More problematic, these simulations neglected cosmic rays and magnetic fields, which provide a comparable pressure support in comparison to turbulence in our Galaxy, and are known to couple dynamically and thermally to the gas. Building - on our previous successes in investigating these high-energy processes, we propose a comprehensive research program for studying the impact of cosmic rays on the formation of galaxies and clusters. To this end, we will study cosmic-ray propagation in - magneto-hydrodynamic turbulence and improve the modeling of the plasma physics. This will enable us to perform the first consistent magneto-hydrodynamical and cosmic-ray simulations in a cosmological framework, something that has just now become - technically feasible. Through the use of an advanced numerical technique that employs a moving mesh for calculating hydrodynamics, we will achieve an unprecedented combination of accuracy, resolution and physical completeness. We complement our - theoretical efforts with a focused observational program on the non-thermal emission of galaxies and clusters, taking advantage of new capabilities at radio to gamma-ray wavelengths and neutrinos. This promises important and potentially - transformative changes of our understanding of galaxy formation." - - 2021-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - CRAGSMAN - - - ERC-2014-CoG - - - 646955 - - - - - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - - - EUR 195 454,80 - - - Liquid Exfoliation of Nanomaterials using Spinning Discs - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Two-dimensional (2D) nanomaterials have received significant attention over the past decade due to their remarkable material properties. Graphene is the most frequently studied, however a range of other 2D materials such as - molybdenum disulfide and boron nitride have also demonstrated properties which will help society advance in areas from opto-electronics to sustainable energy. One of the biggest challenges currently facing 2D nanomaterials is scalable production. - Current exfoliation processes are insufficient for industrial scale production due to high energy requirements, poor yield (typically < 5 wt%), introduction of material defects and low production rates (< 6 g/h). This project aims to address - these process limitations. A novel liquid exfoliation approach will be investigated, using continuous flow over a spinning disc to create mono- and few-layer materials. The research activities will provide a new holistic insight into shear-induced - liquid exfoliation, by experimentally and numerically examining how the fluid mechanics and multiphase transport phenomena over the spinning disc affect material characteristics at the nanoscale. The investigation involves cooperation between - multiple disciplines. Experiments include the optical techniques of infrared thermography, high-speed imagery and particle image velocimetry. The researcher will receive extensive training in advanced numerical methods for simulating thin liquid - films and interfacial flows at Imperial College London. Training in microscopy techniques will also be completed for the measurement of nanosheet defects and size. These research activities will assist the development of future liquid exfoliation - technologies and are aligned with personalised actions to advance career development. The fellowship will broaden the researcher's technical and complimentary expertise, and facilitate inter-sectoral mobility from thermal to chemical engineering, - nanotechnology and process intensification. - - 2019-01-08, ongoing project - - - 2017-01-09 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - LENSD - - - H2020-MSCA-IF-2015 - - - 707340 - - - - - TECHNISCHE UNIVERSITAET MUENCHEN - TECHNISCHE UNIVERSITAET MUENCHEN - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 497 600 - - - Neural processing of context-dependent innate behavior - - - EUR 1 497 600 - - - Germany - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - How do we decide what to choose? While certain cues are preferred, others are avoided. But even innate preferences and aversions must be evaluated in a context-dependent manner. These contexts are environmental cues, but also - internal state. In this proposal, I will address how the nervous system integrates chemosensory information with internal state to produce appropriate behaviors. I will present a research program relying on fly genetics, behavior analysis, and in - vivo physiology to characterize the neural circuits and mechanisms involved in context-dependent processing of sensory cues. Specifically, I will address how three different internal states (hunger, mating state, sickness) change the perception and - processing of odors and tastes. - - 2020-06-30, ongoing project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - FlyContext - - - ERC-2014-STG - - - 637472 - - - - - FORSCHUNGSZENTRUM JULICH GMBH - FORSCHUNGSZENTRUM JULICH GMBH - - - EUR 1 482 220 - - - Custom-made biosensors – Accelerating the transition to a bio-based economy - - - EUR 1 482 220 - - - Germany - Germany - - - Research Organisations - Research Organisations - - How will we meet the globally growing demand for pharmaceutically active compounds, nutrients and fine chemicals when crude oil resources are dwindling? For decades, biotechnologists have been engineering microorganisms to - produce valuable compounds from sugar and biomass. However, a lack of knowledge regarding the host cell metabolism as well as long and laborious development times render this approach challenging to this day. - - 2020-04-30, ongoing project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - CUSTOM-SENSE - - - ERC-2014-STG - - - 638718 - - - - - FORSCHUNGSZENTRUM JULICH GMBH - FORSCHUNGSZENTRUM JULICH GMBH - - - EUR 1 804 663 - - - Proteolytic processing in plant stress signal transduction and responses to abiotic stress and pathogen attack - - - EUR 1 804 663 - - - Germany - Germany - - - Research Organisations - Research Organisations - - Site-specific proteolytic processing is an irreversible post-translational protein modification that generates distinct protein species with new functions, interactions and subcellular locations. In plants, proteolytic - processing regulates hormonal and stress signaling leading to adaptation of metabolic pathways and is implicated in plant-pathogen interactions. Despite their importance, proteolytic processes have largely been identified serendipitously, specific - cleavage sites have rarely been identified and only a few of the hundreds of proteases encoded in plant genomes (>800 in Arabidopsis) have been linked to any substrates. - - 2020-05-31, ongoing project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - ProPlantStress - - - ERC-2014-STG - - - 639905 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 2 251 026,28 - - - From Chemical Bond Forces and Breakage to Macroscopic Fracture of Soft Materials - - - EUR 2 251 026,28 - - - France - France - - - Research Organisations - Research Organisations - - Soft materials are irreplaceable in engineering applications where large reversible deformations are needed, and in life sciences to mimic ever more closely or replace a variety of living tissues. While mechanical strength may - not be essential for all applications, excessive brittleness is a strong limitation. Yet predicting if a soft material will be tough or brittle from its molecular composition or structure relies on empirical concepts due to the lack of proper tools - to detect the damage occurring to the material before it breaks. Taking advantage of the recent advances in materials science and mechanochemistry, we propose a ground-breaking method to investigate the mechanisms of fracture of tough soft materials. - To achieve this objective we will use a series of model materials containing a variable population of internal sacrificial bonds that break before the material fails macroscopically, and use a combination of advanced characterization techniques and - molecular probes to map stress, strain, bond breakage and structure in a region ~100 µm in size ahead of the propagating crack. By using mechanoluminescent and mechanophore molecules incorporated in the model material in selected positions, confocal - laser microscopy, digital image correlation and small-angle X-ray scattering we will gain an unprecedented molecular understanding of where and when bonds break as the material fails and the crack propagates, and will then be able to establish a - direct relation between the architecture of soft polymer networks and their fracture energy, leading to a new molecular and multi-scale vision of macroscopic fracture of soft materials. Such advances will be invaluable to guide materials chemists to - design and develop better and more finely tuned soft but tough and sometimes self-healing materials to replace living tissues (in bio engineering) and make lightweight tough and flexible parts for energy efficient transport. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - France - - - chemech - - - ERC-2015-AdG - - - 695351 - - - - - FORSCHUNGSZENTRUM JULICH GMBH - FORSCHUNGSZENTRUM JULICH GMBH - - - EUR 1 850 000 - - - Simulation and Understanding of the Atmospheric Radical Budget for Regions with Large Emissions from Plants - - - EUR 1 850 000 - - - Germany - Germany - - - Research Organisations - Research Organisations - - Atmospheric pollutants emitted by natural and anthropogenic sources influence significantly the quality of life on our planet. Their removal in the atmosphere is controlled by their reactions with photochemically produced - hydroxyl radicals. Recent findings from experimental studies and quantum-chemical calculations suggest that an important part of atmospheric radical chemistry, which is directly linked to the self-cleansing ability of our atmosphere, has been - overlooked. This causes considerable uncertainty in our understanding of the couplings between the biosphere, atmospheric chemistry and climate. The greatest impact of this lack of understanding has been found for regions with large emissions of - organic compounds from plants in remote or rural areas. - - 2021-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - SARLEP - - - ERC-2015-CoG - - - 681529 - - - - - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 2 499 144 - - - The Genetics and Physiology of Growth and Size Determination - - - EUR 2 499 144 - - - France - France - France - - - Research Organisations - Research Organisations - Research Organisations - - Body size is an intrinsic property of living organisms that is intimately linked to the developmental program to produce fit individuals with proper proportions. Final size is the result of both genetic determinants and - sophisticated mechanisms adapting size to available resources. Classical regeneration and transplantation experiments have established that different body parts grow according to autonomous programs, challenging the concept of systemic and harmonious - growth. Therefore, coordination mechanisms must ensure that all parts have reached appropriate final size before animals stop growing. The main objective of this program is to tackle the mechanisms ensuring growth coordination and size determination. - To tackle these questions, we propose to bring together physiology, genetics, advanced imaging and modelling approaches in an unprecedented integrated project. We will develop these approaches on the Drosophila model where we gained expertise, and - will develop the vertebrate model Ambystoma mexicanum (axolotl) well adapted for limb growth and regeneration studies. Three major aims will be addressed: - - 2021-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - France - - - VitruVius - - - ERC-2015-AdG - - - 694677 - - - - - STAFFORDSHIRE UNIVERSITY - - - EUR 183 454,80 - - - Digital Forensic Archaeology - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The examination of physical evidence and the environment in which it is found remains pivotal in the investigation of crime. There has also been a greater appreciation in recent years of the role of archaeologists in forensic - contexts where buried or concealed evidence exists. - - - 2019-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - Dig-For-Arch - - - H2020-MSCA-IF-2015 - - - 708974 - - - - - ECOLE SUPERIEURE DE PHYSIQUE ET DECHIMIE INDUSTRIELLES DE LA VILLE DEPARIS - - - EUR 92 538 - - - Development of novel fluorinated reagents for preparation of drugs. - - - EUR 92 538 - - - France - - - Higher or Secondary Education Establishments - - Around 20% of all modern drugs are fluorinated organic molecules. During the recent years, however, pharmaceutical companies struggle to deliver novel drugs to the market, because of the lack of innovative practical reagents - and reactions towards “drug-like” compounds. - - - 2016-10-31, closed project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - FLUNOVELTY - - - H2020-MSCA-IF-2014 - - - 654260 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - FORSCHUNGSZENTRUM JULICH GMBH - TECHNISCHE UNIVERSITEIT EINDHOVEN - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - TEIJIN ARAMID BV - UNILEVER RESEARCH AND DEVELOPMENT VLAARDINGEN BV - ASSOCIATION POUR LE DEVELOPPEMENT DE L'ENSEIGNEMENT ET DES RECHERCHES AUPRES DES UNIVERSITES, DES CENTRES DE RECHERCHE ET DES ENTREPRISES D'AQUITAINE - - - EUR 3 613 194,36 - - - Directed Colloidal Structure at the Meso-Scale - - - EUR 3 613 194,36 - - - United Kingdom - Germany - Netherlands - France - Greece - Netherlands - Netherlands - France - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - - Fluid dispersions containing highly elongated colloidal particles form a plethora of ordered, liquid-crystalline states as well as glassy and gel-like disordered states already at very low concentrations. In spite of their - remarkable properties, industrial applications of such dispersions have entered the market only relatively recently, in contrast to more conventional low-molecular-weight, liquid-crystalline fluids for which the major practical applications are in - opto-electronic device technology, e.g., in displays, optical imaging and smart glass. Important potential applications of colloidal liquid crystals can be found in the manufacturing of high-performance fibres and in fast moving consumer goods, such - as foods and home and personal care. - - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - DiStruc - - - H2020-MSCA-ITN-2014 - - - 641839 - - - - - FORSCHUNGSZENTRUM JULICH GMBH - FORSCHUNGSZENTRUM JULICH GMBH - - - EUR 1 994 879 - - - Dynamical magnetic excitations with spin-orbit interaction in realistic nanostructures - - - EUR 1 994 879 - - - Germany - Germany - - - Research Organisations - Research Organisations - - Nano-spin-orbitronics is an emerging and fast growing field that aims at combining three degrees of freedom − spin, charge and spin-orbit interaction − to explore new nanotechnologies stemming from fundamental physics. New - magnetic phases of matter are investigated using, in particular, atomic design to tailor beneficial physical properties down to the atomic level. Storage, transport and manipulation of magnetic information within a small set of atoms does not only - require a fundamental understanding of their ground-state properties from the perspective of quantum mechanics, but crucially also their dynamical excited states. We propose to go beyond the state of the art by investigating from first-principles the - dynamical properties of chiral spin textures in nanostructures from 2-dimensions to 0-dimension with these nanostructures being deposited on different substrates where spin-orbit interaction plays a major role. Understanding their response to - external dynamical fields (electric/magnetic) or currents will impact on the burgeoning field of nano-spin-orbitronics. Indeed, to achieve efficient manipulation of nano-sized functional spin textures, it is imperative to exploit and understand their - resonant motion, analogous to the role of ferromagnetic resonance in spintronics. A magnetic skyrmion is an example of a spin-swirling texture characterized by a topological number that will be explored. This spin state has huge potential in - nanotechnologies thanks to the low spin currents needed to manipulate it. Based on time-dependent density functional theory and many-body perturbation theory, our innovative scheme will deliver a paradigm shift with respect to existing theoretical - methodologies and will provide a fundamental understanding of: (i) the occurrence of chiral spin textures in reduced dimensions, (ii) their dynamical spin-excitation spectra and the coupling of the different excitation degrees of freedom and (iii) - their impact on the electronic structure. - - 2021-05-31, ongoing project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - Dynasore - - - ERC-2015-CoG - - - 681405 - - - - - CONSIGLIO NAZIONALE DELLE RICERCHE - SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI DI TRIESTE - FUNDACIO INSTITUT CATALA DE NANOCIENCIA I NANOTECNOLOGIA - FORSCHUNGSZENTRUM JULICH GMBH - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - CINECA CONSORZIO INTERUNIVERSITARIO - BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION - Eidgenössische Technische Hochschule Zürich - KUNGLIGA TEKNISKA HOEGSKOLAN - E4 COMPUTER ENGINEERING SPA - CLOUDWEAVERS LTD - UNITED NATIONS EDUCATIONAL, SCIENTIFIC AND CULTURAL ORGANIZATION -UNESCO - - - EUR 4 068 863,75 - - - Materials design at the eXascale - - - EUR 4 068 863,75 - - - Italy - Italy - Spain - Germany - Switzerland - Italy - Spain - Switzerland - Sweden - Italy - United Kingdom - France - - - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - - Materials are crucial to scientific and technological advances and industrial competitiveness, and to tackle key societal challenges - from energy and environment to health care, information and communications, manufacturing, - safety and transportation. - - 2018-02-28, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.3."> - - - EINFRA-5-2015 - Centres of Excellence for computing applications - - - RIA - Research and Innovation action - - - Italy - - - MaX - - - H2020-EINFRA-2015-1 - - - 676598 - - - - - INSTITUTE OF PHYSICS OF NATIONAL ACADEMY OF SCIENCE OF UKRAINE - UNIVERSITE DE FRANCHE-COMTE - LATVIJAS UNIVERSITATES CIETVIELU FIZIKAS INSTITUTS - TARTU ULIKOOL - MATERIALS RESEARCH CENTER - - - EUR 202 500 - - - The influence of the cell membrane asymmetry and curvature on the functioning of membrane proteins and the transport of therapeutic compounds - - - EUR 202 500 - - - Ukraine - France - Latvia - Estonia - Ukraine - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Real cell membranes are essentially asymmetric and non-planar. Outer leaflets of the plasma membranes contain neutral lipids and glycolipids, while the inner leaflets host practically all anionic lipids and phosphoinositides. - In addition to asymmetric composition the membranes are usually curved due to spontaneous curvature of the membrane lipids and an influence of membrane proteins and cytoskeleton. There are many cellular phenomena, which are influenced by the - asymmetry and the membrane curvature such as formation of synaptic vesicles, blebs and apoptotic bodies, membrane fusion and splitting, budding of enveloped viruses, endo and exocytosis, etc. - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Ukraine - - - assymcurv - - - H2020-MSCA-RISE-2015 - - - 690853 - - - - - THE UNIVERSITY OF SHEFFIELD - - - EUR 195 454,80 - - - Balancing the immune response in cystic fibrosis: using zebrafish models of infection and inflammation to uncover new therapeutic approaches - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Cystic fibrosis (CF) is a life-limiting disorder caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Chronic pulmonary infections accompanied by persistent neutrophil-dominated - inflammation result in severe progressive lung injury and are the leading causes of morbidity and mortality of CF patients. In addition to known mucociliary defects, several lines of evidence suggest primary alterations in innate immune responses - contribute to CF pathology. Currently, our understanding is limited by the lack of suitable animal models that recapitulate immune abnormalities found in CF patients. To address these unmet needs, I propose to develop zebrafish larvae as a tractable - animal model to investigate the role of CFTR in regulating inflammation and infection. - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - CFZEBRA - - - H2020-MSCA-IF-2016 - - - 751977 - - - - - EUROPEAN UNIVERSITY INSTITUTE - - - EUR 90 138,60 - - - Optimal Taxation of Wealth - - - EUR 90 138,60 - - - Italy - - - Higher or Secondary Education Establishments - - There has been a growing concern in public and academia about rising wealth inequality. In his book Capital in the 21st Century, Thomas Piketty has proposed implementing a global progressive “wealth tax” in order to reduce - wealth inequality. The book has spurred discussions on wealth inequality and made taxation of wealth a subject of current debate. - - 2018-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - Wealth-Taxation - - - H2020-MSCA-IF-2016 - - - 749778 - - - - - EUROPEAN UNIVERSITY INSTITUTE - - - EUR 180 277,20 - - - The Age of Planning. Planning as a paradigm for policy history of post-war Europe: national cases and the European integration process (1940s-1960s) - - - EUR 180 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - The project aims at defining, conceptualizing and historicizing the paradigm of planning in order to analyze public policies in Western Europe at the national, transnational and supranational level between 1945 and the late - 1960s. The fields of public policies covered by the project are economic planning, social planning, urban/spatial planning. - - 2020-04-30, Grant Agreement signed - - - 2018-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - PLANAGE - - - H2020-MSCA-IF-2016 - - - 750887 - - - - - ECOLE SUPERIEURE DE PHYSIQUE ET DECHIMIE INDUSTRIELLES DE LA VILLE DEPARIS - - - EUR 2 354 400 - - - PhD Programme of Advanced Research in Interdisciplinary Science at ESPCI Paris - - - EUR 4 708 800 - - - France - - - Higher or Secondary Education Establishments - - Loyal to its tradition in education and training on an interdisciplinary level between physics, chemistry and biology, ESPCI proposes a brand new international doctoral programme – UPtoPARIS. PhD fellows will have the - opportunity to explore a unique environment comprising an elite engineer school, 9 joint research units and a new incubator on campus hosting 12 technology-driven start-ups – a recipe for a cutting-edge doctoral training in the heart of Paris. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2016 - Co-funding of regional, national and international programmes - - - MSCA-COFUND-DP - Doctoral programmes - - - France - - - UPtoPARIS - - - H2020-MSCA-COFUND-2016 - - - 754387 - - - - - IFOM FONDAZIONE ISTITUTO FIRC DI ONCOLOGIA MOLECOLARE - - - EUR 168 277,20 - - - Regulation and reprogramming of alternative splicing in cellular transformation - - - EUR 168 277,20 - - - Italy - - - Research Organisations - - Alternative splicing (AS), by affecting nearly 90 percent of human genes, is the major contributor to protein diversity. Mutations that disrupt AS regulatory sequences are a widespread source of human diseases. Various - evidences suggest that an AS reprogramming is critical in cell adaptation during cancer development. In spite of increasing interest in the potential oncogenic role of AS, little is known about the molecular mechanisms behind its deregulation during - the somatic to the cancer cell transformation. - - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - SPLICANCER - - - H2020-MSCA-IF-2016 - - - 752553 - - - - - UNIVERSITEIT GENT - ECOLE SUPERIEURE DE PHYSIQUE ET DECHIMIE INDUSTRIELLES DE LA VILLE DEPARIS - TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY - INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM - FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG - SINGLE QUANTUM BV - UNIVERSITEIT UTRECHT - - - EUR 3 056 430,24 - - - Nanophotonics by Nanocrystals, from integration to single photon operation - - - EUR 3 056 430,24 - - - Belgium - France - Israel - Belgium - Germany - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - Phonsi is a research and training program on the development of nanophotonic devices by means of colloidal nanocrystals. Working at the cross-roads of nanomaterials and nanophotonics, it brings together multinational and - start-up companies with universities and research institutes around a research programme combining the synthesis and analysis of quantum dots (QDs) with the formation of QD-based nanophotonic devices for emitting and detecting light down to the - single photon level. The consortium contains complementary, world-leading expertise that crosses research disciplines, attitudes and methodologies such as chemistry/physics/engineering, synthesis/analysis/simulation, lab-scale/industrial scale and - scientific discoveries/research valorization. At each level, the project is driven by highly challenging and timely research goals, which are translated into well-defined, collaborative training-through-research projects. These train ESRs in - different disciplines, give them the opportunity to work with high end scientific instrumentation and expose them to both academic and non-academic research environments. The research projects are complemented by a varied set of network-wide training - events that rely on the active involvement of the trainees and stimulate their self-learning capabilities. Local specialist training addresses complementary skills, which trainees will put into practice by contributing to the training events and - dedicated public engagement activities. The deep involvement of non-academic partners, including two recently established spin-offs, creates a vibrant research and training environment that fosters a spirit of research valorization. In this way, the - program will enable Europe to train ESRs with the multidisciplinary skills in nanomaterials, nanotechnology and photonics the innovation union needs and to raise public interest in these fields of science and technology that are key to make our - future way of living sustainable and comfortable. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Belgium - - - Phonsi - - - H2020-MSCA-ITN-2014 - - - 642656 - - - - - CHARITE - UNIVERSITAETSMEDIZIN BERLIN - CHARITE - UNIVERSITAETSMEDIZIN BERLIN - - - EUR 1 491 235 - - - Deep imaging with time-reversed light - - - EUR 1 491 235 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Microscopy enabled the birth of modern neuroscience, by allowing Ramón y Cajal to formulate the neuron doctrine. Since then, remarkable advances in optical resolution, speed and probe development allowed scientists to study - the function of neuronal circuits with ever increasing detail – with one critical limitation: No conventional microscope can focus light deeper into intact tissue than a fraction of a mm. This leaves 90% of the intact rodent brain and over 99% of the - intact primate brain inaccessible. As a result, the deepest layers of the neocortex and nearly all subcortical structures are currently outside the reach of non-invasive microscopy, representing a fundamental barrier towards further progress in - understanding the brain. - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - DeepLight - - - ERC-2016-STG - - - 714560 - - - - - ALBERT-LUDWIGS-UNIVERSITAET FREIBURG - ALBERT-LUDWIGS-UNIVERSITAET FREIBURG - - - EUR 2 498 750 - - - Beyond the Silk Road: Economic Development, Frontier Zones and Inter-Imperiality in the Afro-Eurasian World Region, 300 BCE to 300 CE - - - EUR 2 498 750 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This interdisciplinary project will show that inter-imperial zones and small to mid-size regional networks of exchange were crucial for ancient Transeurasian exchange connections. It will demonstrate the significance of - exchange in imperial frontier zones emerging from political, economic, infrastructural, institutional and technological development within empires. This will lead to a new conceptual frame for analyzing inter-imperiality and the morphology of - exchange networks within and across imperial zones. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - BaSaR - - - ERC-2016-ADG - - - 742645 - - - - - Eidgenössische Technische Hochschule Zürich - Eidgenössische Technische Hochschule Zürich - - - EUR 2 311 696 - - - Nanoscale Vibrational Spectroscopy of Sensitive 2D Molecular Materials - - - EUR 2 311 696 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - I propose to investigate the nanometer scale organization of delicate 2-dimensional molecular materials using nanoscale vibrational spectroscopy. 2D structures are of great scientific and technological importance, for example - as novel materials (graphene, MoS2, WS2, etc.), and in the form of biological membranes and synthetic 2D-polymers. Powerful methods for their analysis and imaging with molecular selectivity and sufficient spatial resolution, however, are lacking. - Tip-enhanced Raman spectroscopy (TERS) allows label-free spectroscopic identification of molecular species, with ≈10 nm spatial resolution, and with single molecule sensitivity for strong Raman scatterers. So far, however, TERS is not being carried - out in liquids, which is the natural environment for membranes, and its application to poor Raman scatterers such as components of 2D polymers, lipids, or other membrane compounds (proteins, sugars) is difficult. TERS has the potential to overcome - the restrictions of other optical/spectroscopic methods to study 2D materials, namely (i) insufficient spatial resolution of diffraction-limited optical methods; (ii) the need for labelling for all methods relying on fluorescence; and (iii) the - inability of some methods to work in liquids. I propose to address a number of scientific questions associated with the spatial organization, and the occurrence of defects in sensitive 2D molecular materials. The success of these studies will also - rely critically on technical innovations of TERS that notably address the problem of energy dissipation. This will for the first time allow its application to study of complex, delicate 2D molecular systems without photochemical damage. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Switzerland - - - 2DNanoSpec - - - ERC-2016-ADG - - - 741431 - - - - - ECOLE SUPERIEURE DE PHYSIQUE ET DECHIMIE INDUSTRIELLES DE LA VILLE DEPARIS - - - EUR 173 076 - - - Using the Evolution Machine to determine the mechanism of a novel Phage-Induced High-Cell-Density (PIHCD) phenotype - - - EUR 173 076 - - - France - - - Higher or Secondary Education Establishments - - Bacteriophages (phages) drive the evolution of bacteria by antagonistic coevolution and by promoting transfer of genetic material between bacteria. Phages are intimately involved in a range of biological processes from carbon - cycling to the maintenance of human health. Despite their global importance the coevolution between natural phage communities and their bacterial hosts remains poorly understood. This project seeks to understand the mechanism behind a Phage-Induced - High-Cell-Density (PIHCD) phenotype using a droplet-based microfluidic device termed the Evolution Machine, developed at the proposed institution (ESPCI Paris). Work Package 1 (WP1) will use the Evolution Machine to determine and characterize the - phage(s) responsible for the PIHCD phenotype through coinfection with their Pseudomonas fluorescens host. WP2 will determine the mechanistic basis of the PIHCD phenotype using transcriptomics and genetic manipulation. Finally, in WP3 the long term - coevolution between phage(s) and host will be investigated using the droplet-level selection capabilities of the Evolution Machine combined with comparative genomic analysis. Through this fellowship ESPCI Paris will gain from my expertise in - molecular biology and bioinformatics while I will develop new skills in microbiology (phage-host coevolution and genetic manipulation) and microfluidic technology (Evolution Machine). - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - EvoMachine-Phage - - - H2020-MSCA-IF-2016 - - - 747527 - - - - - ECOLE SUPERIEURE DE PHYSIQUE ET DECHIMIE INDUSTRIELLES DE LA VILLE DEPARIS - - - EUR 173 076 - - - A microfluidic high throughput approach to helicase biophysics - - - EUR 173 076 - - - France - - - Higher or Secondary Education Establishments - - We propose a novel high-throughput method to study the chemo-mechanical coupling in molecular motors using helicases, enzymes that couple ATP hydrolysis to unwinding of the double helix, as a model system. The method combines - a cell-free expression system, droplet microfluidics and fluorescent assays with next generation sequencing to test large (up to millions of elements) libraries of helicase mutants for both unwinding and ATPase activity. The aim is to identify all - sequence positions that, if mutated, lead to uncoupling, i.e. abolish unwinding while preserving ATPase activity. Once these positions are identified, their distribution on the enzyme sequence and structure will be analysed to obtain insight into the - coupling mechanism. Notably the methodology could be applied to systems where the classical, structure-based analysis of the chemo-mechanical coupling is not possible. We will demonstrate our method on the RecQ helicase from e. coli using existing - information on this system as a means of validation. Any further insight will be a demonstration of the power of our approach. When fully developed, our method will serve as a discovery tool for the interdisciplinary community working on helicases - that includes medical, biological and physical sciences. It may be applied to aspects of helicase biophysics beyond the chemo-mechanical coupling, to other enzyme families and to screen for helicase inhibitors with higher throughput and lower cost - when compared to robotic mictotitre-plate techniques. The proposed work will be carried out at the Griffiths Lab (ESPCI Paris) with a secondment at the Crick Institute (London). This project integrates the training in biophysics of the Experienced - Researcher with the expertise of the Host Institution on high-throughput methods and the experience of the Secondment Institution on helicases. The Experienced Researcher will be trained in next generation sequencing and fluorescence-based approaches - to molecular motors. - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - MUTAnTS - - - H2020-MSCA-IF-2016 - - - 749944 - - - - - TECHNISCHE UNIVERSITAT DARMSTADT - TECHNISCHE UNIVERSITAT DARMSTADT - - - EUR 2 499 000 - - - Turning the concept of magnetocaloric cooling on its head - - - EUR 2 499 000 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Twenty years of research in magnetocaloric materials has failed to provide the necessary breakthrough that will lead to a commercial realisation of this technology and satisfy the urgent global need for more efficient - refrigeration. We strongly believe that this is a result of looking in the wrong direction. The cool innov project will achieve this breakthrough by rethinking the whole concept of caloric cooling. We are rejecting the conventional idea of squeezing - the best out of magneto-structural phase-change materials in relatively low magnetic fields, and instead we introduce a second stimulus in the form of pressure so that we can exploit, rather than avoid, the hysteresis that is inherent in these - materials. The hysteresis will allow us to lock-in the magnetisation at saturation as the magnetising field is removed, so that magnetic fields persisting over a large area will no longer be required (instead, we can use a very focused field), and - then demagnetise the material in a second step with an applied stress, enabling us to extract a lot more heat. In this case we only need to apply the magnetic field to a small volume of material, making it a completely new application for - commercially available, high-temperature, YBCO-type, bulk superconducting permanent magnets. With the high-field, multi-stimuli approach proven, we will develop new magneto/mechanocaloric materials that match the new high-field, hysteresis-positive - approach and start to fabricate novel heat-exchanger structures using additive manufacturing, so that we can combine a mechanically sound heat exchanger having a complex geometry with locally tailored, magneto/mechanocaloric properties. The success - of cool innov will be game changing. We are being very ambitious in targeting a revolution in cooling technology, but if we succeed, we will have a huge impact on global energy consumption through greater efficiency, thanks to the novel energy - materials that will be discovered within cool innov. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - cool innov - - - ERC-2016-ADG - - - 743116 - - - - - FUNDACIO PRIVADA INSTITUT CATALA D'INVESTIGACIO QUIMICA - Eidgenössische Technische Hochschule Zürich - UNIVERSITEIT LEIDEN - FUNDACION IMDEA NANOCIENCIA - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - TECHNISCHE UNIVERSITAET WIEN - UNIVERSITAT JAUME I DE CASTELLON - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - TECHNISCHE UNIVERSITAT DARMSTADT - FORSCHUNGSZENTRUM JULICH GMBH - UNIVERSITE DE MONTPELLIER - CONSORZIO INTERUNIVERSITARIO NAZIONALE PER LA SCIENZA E TECNOLOGIA DEI MATERIALI - COVESTRO DEUTSCHLAND AG - - - EUR 7 980 861,25 - - - An Artificial Leaf: a photo-electro-catalytic cell from earth-abundant materials for sustainable solar production of CO2-based chemicals and fuels - - - EUR 7 980 861,25 - - - Spain - Switzerland - Netherlands - Spain - Switzerland - Austria - Spain - United Kingdom - Germany - Germany - France - Italy - Germany - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - A novel concept for a photo-electro-catalytic (PEC) cell able to directly convert water and CO2 into fuels and chemicals (CO2 reduction) and oxygen (water oxidation) using exclusively solar energy will be designed, built, - validated, and optimized. The cell will be constructed from cheap multifunction photo-electrodes able to transform sun irradiation into an electrochemical potential difference (expected efficiency > 12%); ultra-thin layers and nanoparticles of - metal or metal oxide catalysts for both half-cell reactions (expected efficiency > 90%); and stateof- the-art membrane technology for gas/liquid/products separation to match a theoretical target solar to fuels efficiency above 10%. All parts will - be assembled to maximize performance in pH > 7 solution and moderate temperatures (50-80 ºC) as to take advantage of the high stability and favorable kinetics of constituent materials in these conditions. Achieving this goal we will improve the - state-of-the-art of all components for the sake of cell integration: - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.2."> - - - FETPROACT-01-2016 - FET Proactive: emerging themes and communities - - - RIA - Research and Innovation action - - - Spain - - - A-LEAF - - - FETPROACT-2016 - - - 732840 - - - - - UNIVERSITEIT GENT - UNIVERSITEIT GENT - MUSEE ROYAL DE L'AFRIQUE CENTRALE - - - EUR 1 997 500 - - - The First Bantu Speakers South of the Rainforest: A Cross-Disciplinary Approach to Human Migration, Language Spread, Climate Change and Early Farming in Late Holocene Central Africa - - - EUR 1 997 500 - - - Belgium - Belgium - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - The Bantu Expansion is not only the main linguistic, cultural and demographic process in Late Holocene Africa. It is also one of the most controversial issues in African History that still has political repercussions today. It - has sparked debate across the disciplines and far beyond Africanist circles in an attempt to understand how the young Bantu language family (ca. 5000 years) could spread over large parts of Central, Eastern and Southern Africa. This massive dispersal - is commonly seen as the result of a single migratory macro-event driven by agriculture, but many questions about the movement and subsistence of ancestral Bantu speakers are still open. They can only be answered through real interdisciplinary - collaboration. This project will unite researchers with outstanding expertise in African archaeology, archaeobotany and historical linguistics to form a unique cross-disciplinary team that will shed new light on the first Bantu-speaking village - communities south of the rainforest. Fieldwork is planned in parts of the Democratic Republic of Congo, the Republic of Congo and Angola that are terra incognita for archaeologists to determine the timing, location and archaeological signature of the - earliest villagers and to establish how they interacted with autochthonous hunter-gatherers. Special attention will be paid to archaeobotanical and palaeoenvironmental data to get an idea of their subsistence, diet and habitat. Historical linguistics - will be pushed beyond the boundaries of vocabulary-based phylogenetics and open new pathways in lexical reconstruction, especially regarding subsistence and land use of early Bantu speakers. Through interuniversity collaboration archaeozoological, - palaeoenvironmental and genetic data and phylogenetic modelling will be brought into the cross-disciplinary approach to acquire a new holistic view on the interconnections between human migration, language spread, climate change and early farming in - Late Holocene Central Africa. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Belgium - - - BantuFirst - - - ERC-2016-COG - - - 724275 - - - - - UNIVERSITY OF EAST ANGLIA - UNIVERSITY OF EAST ANGLIA - - - EUR 3 499 270 - - - COMPASS: Climate-relevant Ocean Measurements and Processes on the Antarctic continental Shelf and Slope - - - EUR 3 499 270 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Processes on the Antarctic continental shelf and slope are crucially important for determining the rate of future sea level rise, setting the properties and volume of dense bottom water exported globally, and regulating the - carbon cycle. Yet our ability to model and predict these processes over future decades remains rudimentary. This deficiency in understanding originates in a lack of observations in this inaccessible region. The COMPASS project seeks to rectify that - by exploiting new technology - autonomous marine vehicles called gliders - to observe, quantify and elucidate processes on the continental shelf and slope of Antarctica that are important for climate. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - COMPASS - - - ERC-2016-ADG - - - 741120 - - - - - CARDIFF UNIVERSITY - - - EUR 183 454,80 - - - Advanced Superlattice Infrared detectors for Space Applications - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - In space, infrared detectors are used for many applications such as Earth observation, post-launch satellite tracking, space-object surveillance or climate monitoring. According to the Planck's law, cold object detection - requires a material with a longer wavelength λ to address the Very LongWavelength InfraRed (VLWIR, λ > 12 μm) spectral domain. The current state-of-the-art includes the Mercury-Cadmium-Telluride (HgCdTe) material. Although, the HgCdTe technology - is already well established and manufactured by many European companies, it suffers from poor uniformity, stability and operability at longer wavelength due to compositional issues caused by the strong dependence of the energy bandgap with the - Cadmium mole fraction. Efforts have therefore been driven to develop alternative infrared materials such as the Type-II InAs/GaSb SuperLattice (T2SL) that can theoretically outperform the HgCdTe technology. Even though, the T2SL has proven to be a - successful approach in the mid-IR and long-IR, extending the cut-off wavelength to the VLWIR range is a new challenge to take up. The VLWIR-T2SL technology will be developed in the newly-established Institute for Compound Semiconductor (ICS) - laboratories at Cardiff University (CU). If successful, this fellowship will produce a real breakthrough in the field of infrared detectors. The VLWIR-T2SL technology has a strong industrial potential, the candidate will thus engage European - collaborators in early stage to demonstrate a focal plane array. This will lead to a reliable route to commercialise devices through the newly-funded Compound Semiconductor Centre. This fellowship will leverage the large investments by the Welsh and - UK government and CU in the general area of compound semiconductor. The candidate will have the managerial and technical support from Prof. Diana Huffaker, as well as staff members of ICS and the School of Physics and Astronomy. - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ASISA - - - H2020-MSCA-IF-2016 - - - 743521 - - - - - ECOLE SUPERIEURE DE PHYSIQUE ET DECHIMIE INDUSTRIELLES DE LA VILLE DEPARIS - ECOLE SUPERIEURE DE PHYSIQUE ET DECHIMIE INDUSTRIELLES DE LA VILLE DEPARIS - - - EUR 1 656 250 - - - Strongly Correlated Physics and Materials for Energy Technology - - - EUR 1 656 250 - - - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - "Materials where conduction electrons experience strong correlation in their dynamics, are both a challenge to the current quantum theories of matter and a mine for possible technological applications. High-temperature copper- - and iron-based superconductors and heavy-fermions with large thermoelectric responses are examples of materials with high potential impact on energy transmission and storage technologies or high-magnetic field applications. - - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - France - - - StrongCoPhy4Energy - - - ERC-2016-COG - - - 724177 - - - - - FORSCHUNGSZENTRUM JULICH GMBH - ANTON PAAR GMBH - ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOMATERIALES- CIC biomaGUNE - CONSIGLIO NAZIONALE DELLE RICERCHE - CR COMPETENCE AB - DENSSOLUTIONS BV - DWI LEIBNIZ-INSTITUT FUR INTERAKTIVE MATERIALIEN EV - Eidgenössische Technische Hochschule Zürich - EXACT LAB SRL - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - LS INSTRUMENTS AG - LUNDS UNIVERSITET - NANOSURF GMBH - PAUL SCHERRER INSTITUT - SYMO-CHEM BV - THE UNIVERSITY OF EDINBURGH - UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA - UNIVERSITAET BAYREUTH - UNIVERSITE DES SCIENCES ET TECHNOLOGIES DE LILLE - LILLE I - UNIVERSITEIT ANTWERPEN - UNIWERSYTET IM. ADAMA MICKIEWICZA W POZNANIU - VISITECH INTERNATIONAL LIMITED - WALBERT WOLFGANG - - - EUR 9 929 470,50 - - - European infrastructure for spectroscopy, scattering and imaging of soft matteer - - - EUR 9 929 470,50 - - - Germany - Austria - Spain - Italy - Sweden - Netherlands - Germany - Switzerland - Italy - Greece - Switzerland - Sweden - Germany - Switzerland - Netherlands - United Kingdom - Spain - Germany - France - Belgium - Poland - United Kingdom - Germany - - - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - EUSMI will provide the community of European soft-matter researchers with an open-access infrastructure as a platform to support and extend their research, covering characterization, synthesis, and modeling. - - - 2021-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.2."> - - - INFRAIA-01-2016-2017 - Integrating Activities for Advanced Communities - - - RIA - Research and Innovation action - - - Germany - - - EUSMI - - - H2020-INFRAIA-2016-1 - - - 731019 - - - - - UNIVERSITAET HAMBURG - UNIVERSITAET HAMBURG - - - EUR 1 500 000 - - - Suspended Fluidic nanochannels as optomechanical sensors for single molecules - - - EUR 1 500 000 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Early detection of cancer saves lives: the survival rate increases from 10% to 90%. Today, there is a lack of methods for the early detection of different types of cancer. The main challenge is that a large variety of specific - biomarkers have to be counted, and usually at extremely low concentrations. - - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - FLUINEMS - - - ERC-2016-STG - - - 714073 - - - - - THE QUEEN'S UNIVERSITY OF BELFAST - FOLKEHELSEINSTITUTTET - THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN - NORGES MILJO-OG BIOVITENSKAPLIGE UNIVERSITET - INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE - Universidad Austral de Chile - VETERINAERINSTITUTTET - NORWEGIAN VETERINARY INSTITUTE - UNIVERSITE DE LIEGE - BioDetection Systems B.V. - PROTOQSAR 2000 SL - - - EUR 3 974 594,76 - - - PROTECTion against Endocrine Disruptors;Detection, mixtures, health effects, risk assessment and communication. - - - EUR 3 974 594,76 - - - United Kingdom - Norway - United Kingdom - Norway - France - Chile - Norway - Belgium - Netherlands - Spain - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - PROTECTED aims to develop expertise and protective capabilities against Endocrine Disruptors (EDs). EDs and their mixtures are a modern day health concern leading to failing ecological systems, poor agricultural production and - health effects such as obesity, cancer and infertility. While analytical methods have advanced enormously, focus has been mainly on synthetic chemicals, overlooking emerging EDs and real-life multiple substance exposure. A new generation of creative, - entrepreneurial and innovative early-stage researchers equipped with skills to assess and understand the real-life risk of complex mixtures of EDs and trained to convert resulting knowledge and ideas into accessible tools and services for the - long-term control of potential ED risk is urgently needed. The PROTECTED Innovative Training Network [ITN] proposes a holistic approach by providing 15 individual, personalised research projects with exposure to scientific, innovative and - entrepreneurial training mobility across the ITN. The intersectorial network is comprised of 12 training sites at academia, research centres, a bioassay technology SME, a QSAR technology SME, water provider, and animal feed supplier. Together they - cover multiple disciplines including analytical science of food, feed, and environment, epidemiology, risk assessment, social science and toxicology. This combined expertise enables a highly focused program for developing novel tools and concepts and - training for the detection, analysis and improved risk assessment of EDs, especially mixture effects. Methodology will include emerging technologies; multiplexed analysis, mixture modelling, mechanistic and exposure studies, explants and cell or - whole organism bioassays. The project will provide a unique and high level of training for a new generation of specialists with transferable skills and enhanced career perspectives. These specialists will ultimately aid the efficient development of - future control strategies for improved health. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - PROTECTED - - - H2020-MSCA-ITN-2016 - - - 722634 - - - - - TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY - TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY - - - EUR 2 493 705 - - - Mechanism Design for Data Science - - - EUR 2 493 705 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The way data science algorithms and techniques, central to the Internet and on-line media, are designed need to be revolutionized. Current designs ignore participants' strategic incentives. Our vision is the establishment of - an entirely new repertoire of incentive-compatible data science algorithms and techniques, obtained through pioneering the application of game-theoretic mechanism design for data science. - - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Israel - - - MDDS - - - ERC-2016-ADG - - - 740435 - - - - - THE UNIVERSITY OF EDINBURGH - THE UNIVERSITY OF EDINBURGH - - - EUR 1 893 626 - - - Honour in classical Greece: esteem, status, identity, and society in ancient Greek literature, life, and thought - - - EUR 1 893 626 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - If ‘honour’ is an outmoded term, its modern analogues – esteem, respect, recognition, dignity, status, prestige, deference, face, image, etc. – still shape the dynamics of human social interaction. But modern understandings of - honour in the societies and literatures of the past – especially the literature of ancient Greece – tend to present it as a single, specific, and more or less monolithic notion especially associated with zero-sum competition between alpha-males, a - notion that is typically superseded by more co-operative, inclusive, and egalitarian values, whether in fifth-century BC Athenian democracy or in the eighteenth-century AD enlightenment. Where honour survives in popular perception as a characteristic - of modern communities it is typically ghettoized in the world of inner-city gangs, in the Muslim East, or in the traditional machismo of the Mediterranean. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - HCG - - - ERC-2016-ADG - - - 741084 - - - - - UNIVERSITEIT GENT - UNIVERSITEIT GENT - - - EUR 2 499 500 - - - Load Slice Core: A Power and Cost-Efficient Microarchitecture for the Future - - - EUR 2 499 500 - - - Belgium - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The ideal processor building block is a power and cost-efficient core that can maximize the extraction of memory hierarchy parallelism, a combination that neither traditional in-order nor out-of-order cores provide. We propose - the Load Slice Core microarchitecture, a restricted out-of-order engine aimed squarely at extracting memory hierarchy parallelism, which, according to preliminary results, delivers a nearly 8 times higher performance per Watt per euro compared to an - out-of-order core. - - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Belgium - - - Load Slice Core - - - ERC-2016-ADG - - - 741097 - - - - - WEIZMANN INSTITUTE OF SCIENCE - WEIZMANN INSTITUTE OF SCIENCE - - - EUR 2 220 000 - - - Delineation of molecular mechanisms underlying the establishment and breakdown of immunological tolerance in the thymus - - - EUR 2 220 000 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Central tolerance is shaped in the thymus, a primary lymphoid organ, where immature T lymphocytes are “educated” into mature cells, capable of recognizing foreign antigens, while tolerating the body’s own components. This - process is driven mainly by two separate lineages of thymic epithelial cells (TECs), the cortical (cTEC) and the medullary (mTEC). While cTECs are critical at the early stages of T cell development, mTECs play a pivotal role in negative selection of - self-reactive thymocytes and the generation of Foxp3+ regulatory T (Treg) cells. Crucial to the key role of mTECs in the screening of self-reactive T cell clones, is their unique capacity to promiscuously express and present almost all self-antigens, - including thousands of tissue-specific antigen (TSA) genes. Strikingly, the expression of most of this TSA repertoire in mTECs is regulated by a single transcriptional regulator called Aire. Indeed, Aire deficiency in mice and human patients results - to multi-organ autoimmunity. Although there has been dramatic progress in our understanding of how thymic epithelial cells shape and govern the establishment of adaptive immunity and of immunological self-tolerance, there are still several - outstanding questions with no comprehensive answers. Therefore, in the research proposed herein, we wish to provide more comprehensive answers to these still elusive, but very fundamental questions. Specifically we will aim at: 1.) Delineation of - molecular mechanisms controlling TEC development and thymus organogenesis; 2.) Delineation of molecular mechanisms underlying promiscuous gene expression in the thymus; 3.) Identification and characterization of molecular determinants responsible for - the breakdown of thymus-dependent self-tolerance. To this end, we will build upon our recently published data, as well as unpublished preliminary data and utilize several state-of-the-art and interdisciplinary approaches, which have become an - integral part of our lab’s toolbox. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Israel - - - ThymusTolerance - - - ERC-2016-COG - - - 724821 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 2 430 140 - - - Large-Scale Formal Proof for the Working Mathematician - - - EUR 2 430 140 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Mathematical proofs have always been prone to error. Today, proofs can be hundreds of pages long and combine results from many specialisms, making them almost impossible to check. One solution is to deploy modern verification - technology. Interactive theorem provers have demonstrated their potential as vehicles for formalising mathematics through achievements such as the verification of the Kepler Conjecture. Proofs done using such tools reach a high standard of - correctness. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - ALEXANDRIA - - - ERC-2016-ADG - - - 742178 - - - - - UNIVERSITEIT GENT - - - EUR 172 800 - - - Development and application of NMR-based tools to inorganic nanocarriers for effective vaccine delivery - - - EUR 172 800 - - - Belgium - - - Higher or Secondary Education Establishments - - There is an urgent need for new vaccines, but avoiding side effects is crucial for patient compliance. To address this, new generation vaccines with safe, but weakly immunogenic antigens are formulated with carriers and - adjuvants to induce the desired immunological response. Inorganic nanoparticles (NP) have shown potential as carriers while immune stimulators of microbial origin are proven to ensure long lasting immune response. Their successful integration into - nanovaccines requires thorough analysis of the inorganic/organic interface. Solution state NMR spectroscopy has recently been established as a potent characterisation tool towards this end. - - - 2019-09-03, ongoing project - - - 2017-09-04 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Belgium - - - NMR4Nanos - - - H2020-MSCA-IF-2015 - - - 703374 - - - - - UNIVERSITE GRENOBLE ALPES - UNIVERSITE GRENOBLE ALPES - - - EUR 2 434 742,51 - - - Seismic Functional Imaging of the Brittle Crust - - - EUR 2 434 742,51 - - - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Despite the dramatic impact of earthquakes, the physics of their onset and the short-term behavior of fault are still poorly understood. Using existing high quality seismic observations, we propose to develop a novel - functional imaging of the brittle crust to clarify not only structural properties but also the dynamics of faults. We will analyze spatio-temporal changes of elastic properties around fault zones to highlight the interplay between changes in the host - rocks and fault slip. Imaging the damage structure around faults and its evolution requires new seismological methods. With novel methods to image the highly heterogeneous fault regions, we will provide multi-scale descriptions of fault zones, - including their laterally variable thicknesses and depth dependence. In parallel we will image temporal changes of seismic velocities and scattering strength. External natural forcing terms (e.g. tides, seasonal hydrologic loadings) will be modeled - to isolate the signals of tectonic origin. This will also allow us to monitor the evolving seismic susceptibility, i.e. a measure of the proximity to a critical state of failure. Improved earthquake detection techniques using ‘deep machine learning’ - methods will facilitate tracking the evolution of rock damage. The imaging and monitoring will provide time-lapse images of elastic moduli, susceptibility and seismicity. The observed short-time changes of the materials will be included in slip - initiation models coupling the weakening of both the friction and the damaged host rocks. Laboratory experiments will shed light on the transition of behavior from granular (shallow fault core) to cohesive (distant host rock) materials. Our initial - data cover two well-studied fault regions of high earthquake probability (Southern California and the Marmara region, Turkey) and an area of induced seismicity (Groningen). The derived results and new versatile imaging and monitoring techniques can - have fundamental social and economic impacts. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - France - - - F-IMAGE - - - ERC-2016-ADG - - - 742335 - - - - - AALTO-KORKEAKOULUSAATIO - - - EUR 191 325,60 - - - Multisensory-Based Spatial Sound - - - EUR 191 325,60 - - - Finland - - - Higher or Secondary Education Establishments - - The worlds of multisensory research and multimedia technologies have originated and, for the most part, still remain largely independent. The first exists mostly within the field of experimental psychology, or psychophysics, - while the second one is mostly studied and developed by engineers. This project aims at implementing this perfect multidisciplinary marriage in the field of acoustics. A series of psychophysical experiments will be carried out at Aalto School of - Engineering, in the Spatial Sound Group, aiming at obtaining detailed guidelines on how to reproduce sound for the best audiovisual experience. The results will be further applied to a new sound spatialization algorithm designed specifically to - enhance human audiovisual experience, while reducing computational complexity where it is not needed. The ultimate goal is to reach every consumer, namely in television, cinema, gaming, computer streaming and teleconferencing applications. Direct - actions to reach the general community, as well as the industry, will ensure maximum practical impact. - - - 2017-10-31, closed project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Finland - - - MULTISSOUND - - - H2020-MSCA-IF-2014 - - - 659114 - - - - - BOURNEMOUTH UNIVERSITY - - - EUR 183 454,80 - - - Predicting adaptive responses of protected species to environmental changes to optimise conservation management frameworks in Europe - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Environmental changes, including habitat loss and climate change, are negatively impacting biodiversity at global levels, with accelerating extinction rates of species. Whilst the EU Biodiversity Strategy aims to halt and then - reverse these losses of species, data on the conservation status of many protected species is lacking, inhibiting their management. Effective conservation is reliant on robust data on protected species, yet there is a substantial knowledge gap - between traditional monitoring methods that record abundances and conservation management frameworks that require the integration of species’ ecology with their adaptive responses to rapidly changing environments. The primary aim of this Fellowship - is to thus deliver a novel conservation management framework for a model protected species, integrating ecological and genetic data, to provide a new predictive basis for European conservation management programmes. The sea lamprey Petromyson marinus - is the model species, a protected species on Annex II of the EU Habitats Directive that provides multiple generations for testing the effects of environmental change on candidate genes. Research objectives quantify P. marinus European genetic - diversity and structure, test for the presence of novel genetic mutations across populations, identify the genetic regions associated with adaptation to specific environmental parameters and develop an eco-evolutionary model of P. marinus population - dynamics as the basis for its conservation management framework. As the project delivers highly innovative genetic and ecological research, it brings together a leading European researcher with high genetic knowledge with a European research group - with exceptional expertise in conservation ecology. Together, their knowledge transfer and training activities will deliver novel conservation tools supporting European conservation strategies and launch a new research agenda in biodiversity and - conservation management. - - 2018-11-13, ongoing project - - - 2016-11-14 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ADAPTATION - - - H2020-MSCA-IF-2015 - - - 705615 - - - - - MEDICAL RESEARCH COUNCIL - - - EUR 183 454,80 - - - Structural role of protein splicing factors in promoting an active configuration of the spliceosome's RNA catalytic core - - - EUR 183 454,80 - - - United Kingdom - - - Research Organisations - - The spliceosome is a ribonucleoprotein machine that excises introns from pre-messenger RNAs. During my phD, I identified RNA ligands for the magnesium ions that catalyze these splicing reactions and showed that the - spliceosomal U6 and U2 small nuclear RNAs form a structure resembling group II self-splicing intron RNAs. Although the spliceosome's catalytic core is RNA-based, numerous spliceosomal proteins promote the proper catalytic fold of this RNA core, - juxtapose the reactive pre-mRNA elements with the U6 metal sites, and regulate spliceosome dynamics during the splicing cycle. Indeed, the Prp8 protein cross-links with the critical nucleotides of the catalytic RNA core and its crystal structure, - reported recently by the host laboratory, revealed a cavity that accommodates the catalytic RNA core. Moreover, several helicases, such as Brr2 and Prp16, promote an active configuration of the U2/U6 RNA core and associated proteins and regulate - their dynamics. The arrangement of such proteins in the assembled spliceosome and their interactions with the RNA core is presently unknown due to the lack of high-resolution structures of any spliceosomal complexes. I will study biochemically in - vitro the interactions between the U2/U6 core and key proteins necessary for an active fold of the RNA core, with the goal of reconstituting and solving the high-resolution structure of a minimal active U2/U6 RNA core in complex with the reactive - pre-mRNA sites and surrounding proteins including Prp8. In parallel, I will employ recent advances in cryo-electron microscopy sample preparation, imaging, and data processing, which were pioneered at the host institute, to obtain high-resolution (at - least 7 Angstroms) three-dimensional reconstructions of endogenous fully assembled spliceosomes stalled at specific splicing stages. These studies promise to provide unprecedented structural insihgt into the configuration and dynamics of key RNA and - protein elements of the spliceosome. - - 2018-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SpliceosomeStructure - - - H2020-MSCA-IF-2014 - - - 657492 - - - - - MEDICAL RESEARCH COUNCIL - - - EUR 183 454,80 - - - Controlled cryo-EM sample preparation through DNA-Origami pillars - - - EUR 183 454,80 - - - United Kingdom - - - Research Organisations - - Electron cryomicroscopy (cryo-EM) is rapidly emerging as a powerful technique for high-resolution structure determination of protein complexes. Despite recent advances, there is still ample room for improvement of this method, - in particular regarding sample preparation. Outstanding challenges are reproducibility of freezing conditions to obtain an optimal ice thickness; to prevent unfolding or preferential orientation of proteins against the hydrophobic air-water - interface; and a limited accuracy of beam-induced motion correction for relatively small particles. Here, we propose to study how DNA origami objects that are added in with the sample may affect cryo-EM grid preparation. In addition, by examining a - variety of DNA origami structures in the electron microscope, we also aim to identify and improve on structural weaknesses in their design. We will test new design strategies, analyse those, and use them for application in cryo-EM. Thereby, this - proposal will facilitate both cryo-EM structure determination and the design of nano-tools that are made from DNA. - - 2017-07-31, closed project - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - EM-Pillars - - - H2020-MSCA-IF-2014 - - - 657990 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 173 076 - - - Mechanisms of stress-induced cognitive deficits : Role of the glucocorticoid receptor and its partners in the regulation of PFC function. - - - EUR 173 076 - - - France - - - Research Organisations - - The prefrontal cortex (PFC) is a locus for higher-order cognition and executive control across species. In most mental disorders such as depression or schizophrenia, dysfunction in PFC and its related neuronal networks has - been associated with a variety of cognitive impairments. Chronic stress exposure and abnormal levels of glucocorticoid stress hormone (GCs) is a key environmental risk factor for psychiatric illness. The PFC is highly vulnerable to stress exposure - and many studies have reported detrimental effects of chronic stress exposure and/or high GCs levels on cognition, however the physiological underpinnings remain poorly understood. GCs exert their action in part by binding the glucocorticoid receptor - (GR), a transcription factor expressed in every cell type. Through a complex interplay with co-factors, GR can modulate the expression of a large set of genes and thereby modify brain circuit physiology ultimately leading to behavioural changes. In - this project, I propose to investigate the molecular and cellular mechanisms through which stress-exposure can modify the activity of PFC and its related networks and lead to cognitive impairment. - - - 2020-01-03, ongoing project - - - 2018-01-04 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - StressPFCog - - - H2020-MSCA-IF-2016 - - - 753296 - - - - - AALBORG UNIVERSITET - - - EUR 200 194,80 - - - Mooring of floating wave energy converters:numerical simulation and uncertainty quantification - - - EUR 200 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - This project aims at designing mooring system for floating wave energy converters (WECs) using a design approach based on numerical uncertainty quantification to estimate loads to a given tolerance level. This approach is to - be compared to traditional deterministic approach with safety factors in terms of cost of the designed system. This is to be achieved by: (i) using an uncertainty quantification (UQ) toolbox based on general polynomial chaos (gPC) into a - state-of-the-art mooring dynamics solver; (ii) to perform detailed numerical investigation on the influence on snap-loads on the mooring design. All parts aim at providing a base for lowering the economic cost of the mooring system. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - MoWE - - - H2020-MSCA-IF-2016 - - - 752031 - - - - - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - - - EUR 2 486 375 - - - The Chemical Basis of RNA Epigenetics - - - EUR 2 486 375 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The genetic code consists of a defined sequence of four canonical nucleosides and the sequence of these bases carries the blueprints of all life on earth. It is apparent that this sequence information alone is not sufficient - to explain how a multicellular organism can establish specialized cells like the 200 known cells types of a human body. For this, a second information layer is required and since a few years, it is apparent that this information layer is strongly - based on Chemistry. Histones, DNA and RNA are the target of sophisticated chemical modification, which establishes a second layer of information. This proposal aims at decoding this chemical code on RNA, specifically on messenger RNA. More than 150 - chemical derivatives of RNA nucleosides are known and many more await discovery. We are proposing a program to study RNA modifications and to decipher their function. We are expecting to answer key questions about the structures, the distribution and - the biological function of numerous known and yet unknown chemical RNA derivatives that brings us deep into unexplored areas of science. Since some of the modified bases equip RNA with yet unknown reactivity we will study the functional aspects of - reactive bases, which allows us to tackle some of the most important questions associated with the RNA world theory. Our results will move Europe into a central position in the new field of RNA epigenetics, which has the potential to become the next - big wave in science 63 years after the discovery of the double helix structure. We are perfectly positioned to move the field forward. We established quantitative methods to study modified bases that uncovered a new biological principles in cancer - cells (Carell, Carmeliet, Lamberts Nature 2016) and we contributed to the RNA world theory (Carell Science 2016). We applied proteomic tools to learn about the function of new DNA bases that we partially even discovered (Carell, Vermeulen Cell 2013; - Carell Nat. Chem. Biol. 2014). - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - EPiR - - - ERC-2016-ADG - - - 741912 - - - - - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - - - EUR 183 454,80 - - - Logic-based Attribution and Forensics in Cyber Security - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Recent studies states that "Devices will continue to grow in volume and variety, and the forecast for connected devices by 2020 is 200 billion and climbing". The increase of connectivity brings a drastic impact on the increase - of cyber attacks. Protecting measurements are not enough, while finding who did the attack is a crucial for preventing the escalation of cyber attacks. - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - AF-Cyber - - - H2020-MSCA-IF-2016 - - - 746667 - - - - - OXFORD BROOKES UNIVERSITY - - - EUR 183 454,80 - - - Innovative learning platform for knowledge integration in Energy Retrofit - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - This proposal revolves around two specific questions: 1) to what extent multidisciplinary strategies to improve energy performance of existing buildings and neighbourhoods can be integrated; and 2) how this integration can - bring technology and sustainable redevelopment of existing buildings together. It aims to develop an innovative learning platform for Knowledge Integration in Energy Retrofit (C-mapER) to develop the skills to manage complexity inherent in retrofit - projects. An alternative method and an associated platform to evaluate and manage complexity, through a novel application of meaningful learning activities in designing technological solutions for energy retrofit, is the main vehicle.The objectives - are to: 1) develop a conceptual framework of the key concepts and relationships that influence Energy Retrofit projects in workpackage 1 (WP1), 2) develop the beta version of the platform (WP2); and 3) test, refine, verify and disseminate the - platform (WP3).The ultimate goal is to revolutionalise the traditional approach to educating future professionals, which is currently based on rote learning. - - - 2019-09-17, ongoing project - - - 2017-09-18 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - C-mapER - - - H2020-MSCA-IF-2016 - - - 751376 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 173 076 - - - Scattering Matrix Approach in Reflection applied to Turbid media - - - EUR 173 076 - - - France - - - Research Organisations - - This project aims to (1) demonstrate innovative optical imaging by increasing by 2x the depth penetration of optical coherence tomography (OCT) and (2) make groundbreaking advances in the study of 3D Anderson localization (AL) - of light. These seemingly different topics are in fact closely linked. Wave transport in complex media can be described by the Green’s matrix (GM), which holds complete information about propagation between every input and output point of the medium. - The need to understand and work with the GM underpins the proposed work of this action. Recently, the field GM for light was measured for the first time using a white-light illumination, opening up new avenues for fundamental and applied physics. - This action will combine this approach with matrix methods (previously applied to ultrasound imaging) to build a ‘SMART-OCT’ apparatus: an innovative OCT-like system based on a matrix approach that enables the acquisition of the GM and elimination of - multiple scattering. SMART-OCT will have 2x the current OCT depth limit (>2 mm) with no loss in resolution or affordability (white light illumination). The SMART-OCT system will be tested on biological tissues, compared to current OCT, and - patented and developed towards market. Like all technology, the creation of this device will be accompanied by advances in fundamental science. The optical field GM will be used to study AL of light – the ‘trapping’ of waves due to interference - effects induced by strong disorder. This concept is important for light control and confinement, but past experiments in optics have always suffered from absorption and non-linearities. The proposed method can sidestep these issues to give the first - unambiguous study of 3D AL for light. The execution of these projects in parallel will develop the sensitivity and range of SMART-OCT. - - 2019-08-17, ongoing project - - - 2017-08-18 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - SMART - - - H2020-MSCA-IF-2016 - - - 744840 - - - - - UNIVERSITY COLLEGE LONDON - - - EUR 183 454,80 - - - Quantum control of levitated nanoparticles - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Coherent control of a macroscopic quantum system is one of the main objectives of the field of optomechanics with potentially game changing implications for fundamental physics as well as technology. On one side it could allow - the exploration of the classical-to-quantum boundary, on the other it could allow the development of quantum limited sensors and provide a fundamental building block for quantum information. - - - 2019-05-14, ongoing project - - - 2017-05-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - QUCLN - - - H2020-MSCA-IF-2016 - - - 749709 - - - - - UNIVERSITY OF LEICESTER - - - EUR 195 454,80 - - - Restoration of motor dysfunction in vivo through nanomaterials based devices - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Spinal cord injury (SCI) and amyotrophic lateral sclerosis (ALS) are nervous system maladies that impair the function of spinal central pattern generators for locomotion. These disorders carry a significant social and economic - burden, owing to a lack of effective therapeutic treatments. In the field of nanotechnology, carbon nanotubes (CNT) have shown outstanding promise for the improvement of neuronal function in vitro and are thus ideal candidates for repairing or - ameliorating spinal defects associated with these disorders. The ultimate goal of this project is to develop CNT as a tool for restoring motor dysfunctions associated with SCI and ALS. Specifically, I will use zebrafish larvae as an in vivo model for - testing the therapeutic efficacy of this innovative class of implantable devices. I will implant CNT and graphene based devices in healthy, spinal cord lesioned and ALS zebrafish models and test their effects on spinal cord function with a range of - powerful in vivo techniques. My project will address three specific aims. First, biocompatibility of implanted devices will be assessed using in vivo patch clamping of spinal motoneurons in healthy fish implanted with nanodevices. Second, I will - implant CNT into fish that have been subjected to SCI. Nanomaterial-facilitated functional recovery will then be tested with in vivo patch clamping of spinal motor neurons, analysis of locomotor behaviour and confocal microscopy. Finally, I will use - similar approaches to determine if implanted CNT can slow or reverse spinal cord defects in a SOD1 mutant zebrafish model of ALS. The project will advance our knowledge in an innovative field of bioscience research and help to inform the development - of alternative approaches to the treatment of SCI and ALS. Embedded in an international environment, such as that of the University of Leicester, I will support my research activity through a greater level of independence, with the aim of publishing - papers as senior author. - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - NanoZfish - - - H2020-MSCA-IF-2016 - - - 747167 - - - - - ANGLIA RUSKIN UNIVERSITY HIGHER EDUCATION CORPORATION - - - EUR 97 727,40 - - - Default meanings in compound interpretation - - - EUR 97 727,40 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Languages always change, and existing words are constantly combined into novel combinations such as ‘trout pout’ or ‘bucket list’. Surprisingly, little is known about the actual processes and resources humans use to understand - these novel combinations. This project will investigate a central question in the field of linguistics, namely the extent to which people rely on inherent meanings of words in combination (lexical semantics), compared with the extent to which they - infer meaning from context (pragmatics). The interdisciplinary nature of the project is strong. It will use a combination of psycholinguistic techniques, with big data from corpus linguistics to empirically test hypotheses derived from - state-of-the-art accounts in theoretical linguistics. Firstly, a questionnaire study will establish the extent to which people vary in their interpretation of different noun-noun combinations, and what determines the degree of variation. The study - will innovatively use a large semantically annotated dataset to generate representative experimental items. Secondly, advanced eye-tracking technology will be used to investigate how these combinations fare when presented in contexts that either - support or do not support a dominant interpretation. Together, the results of the two studies will shed light on the balance of word meaning and context in the interpretation of new combinations and either confirm or refute the underlying assumptions - of competing semantic theories. The results will be of benefit in applications such as the automatic processing and translation of human language, and the assessment of misleading language usage, e.g. in advertising. They will also benefit - theoretical linguists and psycholinguists, by showing how insights from each area can fruitfully be applied to the other. For the researcher, the project offers an invaluable opportunity to train in cutting-edge empirical techniques and gain skills - in public engagement and research communication. - - 2018-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - Demeco - - - H2020-MSCA-IF-2016 - - - 752436 - - - - - UNIVERSITY COLLEGE LONDON - - - EUR 183 454,80 - - - Minimal Model for Pox-Virus Infection - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Viral diseases represent one of the world’s highest socio-economic burdens. Increased global trade and travel, climate change resulting in shifting viral vectors, and the emergence of new and often deadly viruses is - inevitable. Therefore, detailed understanding of the complexity of virus particles and the development of new model systems to study them, will be essential to develop new research, diagnostic, and therapeutic tools. The structural changes that occur - during the initial contact between a virus and its host remains one of the major challenges in infection biology. Until recently, the investigation of viral nano-architecture and dynamic changes that occur in virus particles during the infectious - lifecycle was limited to methods, such as EM, with no capacity to capture dynamic events or define molecular specificity. The goal of the proposed project is to create a new minimal model of virus infection based on cell-derived membrane blebs. The - model will be amenable to novel super-resolution microscopy (SRM) methods that allow the visualization of viral structures at resolutions of tens of nanometers. Recently developed analytical tools like single-virion averaging allows the generation of - precise models from hundreds of events. This affords unprecedented insights into the biological and biophysical requirements of virus infection. Furthermore, we aim to investigate the dynamics of virus architectural changes during the first stages of - infection, particularly at the membrane level, by combining single-molecule techniques with our new model-system. While initially aimed at investigating protein structure-function relationships within the prototypic poxvirus, vaccinia, the model - system and imaging developments outlined will be broadly applicable to a wide range of biological systems including other viruses. Thereby, this proposal looks to advance the field of infection biology into the nanoscale. - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - MMXVI - - - H2020-MSCA-IF-2016 - - - 750673 - - - - - UNIVERSITY OF DURHAM - - - EUR 195 454,80 - - - Inside the Mind of Ancient People: the tangible and constructed landscape of the western Delta in the Late Period (664-332BC) - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - MAP aims to generate an experimental and innovative methodology combining the “sociology of space” critical theory and the archaeological (material and textual) evidence offered by ancient Egyptian society, in order to examine - the constitution of space as product of social action or social structures, and recursively to identify the points of contact where the landscape shaped and changed the mind of people. Ancient Egyptian temple libraries preserve a number of written - records which provide insights into the religious and geographic knowledge. The challenge is not to harmonize written and archeological sources inside a monadic dimension but to measure the differences, as a way to discover multiple and conflicting - stories from the human mind and the actions imposed onto the physical/mental landscape. The “regionally specific sacerdotal” officials during the Late Period (664-332 BC) in the western Delta of Egypt (2nd-7th provinces of Lower Egypt) is adopted as - the research-program case-study, on account of its exceptional significance for archaeology, written sources and lack of any substantive previous research programs. MAP represents an innovative theoretical and methodological contribution for - understanding the interaction between physical geography and the intimate conception/perception of the physical space inside the geography of ancient Egypt. The goals of MAP will be achieved adopting an intradisciplinary methodology, aimed to - reconnect archaeology and philology, through: 1) analysis of the “regionally specific sacerdotal” officials inside written and artifactual sources; 2) landscape archaeology in order to provide a plot map of the physical environment, through which - human entities moved and operated; 3) a comparative dimension aimed to generate a theoretical model, which will open new horizons on how humans and the environment interacted, how the environment changed in the mental process and how the mental - process was entangled in a tangible geography. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - MAP - - - H2020-MSCA-IF-2016 - - - 744977 - - - - - ALBERT-LUDWIGS-UNIVERSITAET FREIBURG - ALBERT-LUDWIGS-UNIVERSITAET FREIBURG - - - EUR 149 981 - - - Hide and Seek with Cancer Drugs - - - EUR 149 981 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Cancer is one of the most prominent causes for morbidity and mortality in industrialized countries. The key challenge in drug-based anti-cancer therapy is to efficiently kill the cancer cells while minimizing side-effects on - healthy parts of the body. The DeShield project will establish the proof of concept for a novel approach to upgrade existing anti-cancer drugs in a way that the anti-cancer effect will be increased while side-effects will simultaneously minimized. - DeShield technology will be used to shield approved anti-cancer drugs while circulating in the body in order to minimize side effects. Once the shielded drug accumulated at the cancer site, an external stimulus will be applied to trigger - de-shielding. The drug will then locally and specifically be taken up by the cancer cells to exert its therapeutic effect. We have successfully demonstrated the functionality of the DeShield technology using the clinically approved anti-cancer drug - Doxil and human cancer cell lines: when the shield is intact, the drug is not taken up by the cells, only upon inducible un-shielding the drug enters and kills the cells. In the DeShield project we aim at establishing the Proof-of-Concept that this - approach is functional in cancer animal models, that it increases the therapeutic effect while minimizing side-effects. To this aim we have assembled a team with high expertise in complementary areas covering the technology itself, the conductance of - preclinical animal studies up to clinical trials as well as business expertise. The technical advance obtained in this project together with a comprehensive market research and the development of a business strategy will shape a highly attractive - commercial proposition for the successful valorization of our ERC-funded research. - - 2018-11-30, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Germany - - - DeShield - - - ERC-2016-PoC - - - 755369 - - - - - Eidgenössische Technische Hochschule Zürich - Eidgenössische Technische Hochschule Zürich - - - EUR 2 500 000 - - - Mass, heat and spin transport in interlinked quantum gases - - - EUR 2 500 000 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The objective of the proposed project is to create a versatile experimental and methodological platform for exploring transport mechanisms with quantum gases. Our approach will enable studying the dynamics of mass, heat and - spin transport between linked reservoirs with a unique degree of control and flexibility, and promises to open up a route to discovering yet-unknown transport phenomena. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Switzerland - - - TransQ - - - ERC-2016-ADG - - - 742579 - - - - - RIJKSUNIVERSITEIT GRONINGEN - RIJKSUNIVERSITEIT GRONINGEN - - - EUR 2 499 974,51 - - - Systems Chemistry: Steps Towards De-Novo Life - - - EUR 2 499 974,51 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Can we synthesise life de-novo in the lab? This is one of the Grand Challenges of contemporary Science. Overall objective of this project is to set important steps in turning chemistry into biology by building fully synthetic - chemical systems that contain and integrate some of the essential elements of life: replication, metabolism and compartmentalisation. Functional coupling of any of life’s essential elements has not been achieved, at least not without making use of - biomolecules. We now aim to achieve such coupling and develop fully chemical systems to become increasingly life-like. Specific aims are: - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Netherlands - - - ToDL - - - ERC-2016-ADG - - - 741774 - - - - - HELSINGIN YLIOPISTO - HELSINGIN YLIOPISTO - - - EUR 1 500 000 - - - Informatics approaches for the rational selection of personalized cancer drug combinations - - - EUR 1 500 000 - - - Finland - Finland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Making cancer treatment more personalized and effective is one of the grand challenges in our health care system. However, many drugs have entered clinical trials but so far showed limited efficacy or induced rapid development - of resistance. We critically need multi-targeted drug combinations, which shall selectively inhibit the cancer cells and block the emergence of drug resistance. This project will develop mathematical and computational tools to identify drug - combinations that can be used to provide personalized and more effective therapeutic strategies that may prevent acquired resistance. Utilizing molecular profiling and pharmacological screening data from patient-derived leukaemia and ovarian cancer - samples, I will develop model-based clustering methods for identification of patient subgroups that are differentially responsive to first-line chemotherapy. For patients resistant to chemotherapy, I will develop network modelling approaches to - predict the most potential drug combinations by understanding the underlying drug target interactions. The drug combination prediction will be made for each patient and will be validated using a preclinical drug testing platform on patient samples. I - will explore the drug combination screen data to identify significant synergy at the therapeutically relevant doses. The drug combination hits will be mapped into signalling networks to infer their mechanisms. Drug combinations with selective - efficacy in individual patient samples or in sample subgroups will be further translated into in treatment options by clinical collaborators. This will lead to novel and personalized strategies to treat cancer patients. - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Finland - - - DrugComb - - - ERC-2016-STG - - - 716063 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - - - EUR 148 619 - - - Plants as sensors for standardization and calibration of controlled environment chambers - - - EUR 148 619 - - - Ireland - Ireland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Research in plant biology & crop breeding conducted in controlled environment chambers (CECs) require that observed differences in measured plant traits between or within CECs are attributable to the imposed experimental - treatment or breeding protocol rather than to heterogeneity and/or poor accuracy in the monitoring of different chamber environmental conditions. To date, no commercial product has been developed which tests standardization of environmental - conditions within and between CECs of the same manufacturer or between different manufacturers. The cost per chamber of deploying a full artificial sensor network to test for homogeneity of CEC conditions would be thousands of euros per CEC; a - prohibitive cost for users and manufacturers alike. This Proof of Concept grant will develop and commercialize the first plant-based sensor kit for standardization and calibration of CECs used in plant research, commercial horticulture and by the - international plant breeding sector (BAYER Crop Science, MONSANTO etc.) at one tenth of the cost of an artificial sensor network and with equal or better environmental sensing capacity. Commercialization of PlantSenseKit will be via a license - agreement to a commercial partner and involve comprehensive market research, competitor analysis, and further technological refinement of the PlantSenseKit protocol, prototype testing & development of a business plan. This Proof of Concept grant - will have a positive impact on society and economic activities by improving the performance of infrastructure used in food security and climate change research and by providing new jobs for Ireland via commercialization of PlantSenseKit. - - 2019-02-28, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Ireland - - - PlantSenseKit - - - ERC-2016-PoC - - - 727578 - - - - - AALTO-KORKEAKOULUSAATIO - AALTO-KORKEAKOULUSAATIO - - - EUR 2 418 002 - - - Superconducting quantum heat engines and refrigerators - - - EUR 2 418 002 - - - Finland - Finland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The aim of the proposed work is to realize experimentally the first genuinely quantum mechanical refrigerator/heat engine in the solid state, and test whether one can boost its performance by information/feedback, optimized - control, and merely by exploiting the quantum coherences vs the classical dynamics. To achieve this goal, we will investigate experimentally and theoretically the thermodynamics of open quantum systems. For the experimental realization, we will - develop calorimetry with superior energy and time resolution and build competitive quantum circuits based on superconducting quantum bits (qubits). In order to achieve the ultimate goal, we will, for the first time, implement a test for quantum - fluctuation relations in a truly open quantum system, and demonstrate an implementation of the so-called quantum Maxwell's Demon by controlling a qubit in an optimal way. In our studies we will utilize the state-of-the-art nanofabrication and - measurement facilities of the national OtaNano research infrastructure that I coordinate. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Finland - - - SQH - - - ERC-2016-ADG - - - 742559 - - - - - UNIVERSITEIT VAN AMSTERDAM - UNIVERSITEIT VAN AMSTERDAM - - - EUR 2 444 446 - - - Dynamics of Probed, Pulsed, Quenched and Driven Integrable Quantum Systems - - - EUR 2 444 446 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This proposal intends to develop and apply a new-generation theoretical toolbox for understanding the rich dynamics of strongly-interacting many-body quantum sytems subjected to destabilizing manipulations bringing them very far from equilibrium. - - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Netherlands - - - DYNAMINT - - - ERC-2016-ADG - - - 743032 - - - - - STICHTING VU - EVERCYTE GMBH - UNIVERSITE D'ARTOIS - UNIVERSITE DE LAUSANNE - BIOTALENTUM TUDASFEJLESZTO KFT - KATHOLIEKE UNIVERSITEIT LEUVEN - Department of Health - Newcells Biotech Limited - ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI - LIVERPOOL JOHN MOORES UNIVERSITY - KEMIJSKI INSTITUT - UNIVERSITEIT UTRECHT - DOUGLAS CONNECT GMBH - MEDIZINISCHE UNIVERSITAT INNSBRUCK - - - EUR 3 860 843,40 - - - An integrated interdisciplinary approach to animal-free chemical and nanomaterial safety assessment - - - EUR 3 860 843,40 - - - Netherlands - Austria - France - Switzerland - Hungary - Belgium - United Kingdom - United Kingdom - Italy - United Kingdom - Slovenia - Netherlands - Switzerland - Austria - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - All chemicals whether they are drugs, cosmetics, agrochemicals or others need to be tested for their safety to man and the environment. The use of whole animal studies for the prediction of adverse effects in man, is - problematic due to species dependent effects, high costs and a large burden to animals in terms of numbers and suffering. While there have been major improvements in human in vitro and in silico techniques, there is still a lack of an integrated risk - assessment platform. The in3 proposal aims to significantly further the development of animal-free chemical and nanomaterial (NM) safety evaluation by creating a scientific and training program aimed at integrating human in vitro testing with - computational approaches. The project will focus on human induced pluripotent stem cells (hiPSC) derived tissues, including liver, kidney, brain, lung and vasculature and to utilise mechanistic toxicology, quantitative adverse outcome pathways, - biokinetics, cheminformatics and modelling approaches to derive testable prediction models. hiPSC present the major advantages provide non-cancerous derived tissues with identical genetic backgrounds. All Early Stage Researchers (ESRs) will work - towards the same goal, utilising the same chemicals, donor cells, assays and software packages. All data will be centrally housed in standardised formats, appropriately annotated and linked with protocols and material information. While ESRs will - hone their skills in their own field of expertise, they will also collaborate to create an in depth safety evaluation testing platform for the chosen test compounds. By interaction, problem solving, training and secondments over the three years, they - will acquire a unique set of interdisciplinary skills for chemical and NM safety assessment. The project aims to accelerate the realisation of animal-free safety assessment and to graduate 15 PhD students with the ideal skill sets to carry out the - strategy designed in in3 in the near future. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Netherlands - - - in3 - - - H2020-MSCA-ITN-2016 - - - 721975 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 240 318 - - - Structure-performance relationships in porous carbons for energy storage - - - EUR 1 240 318 - - - France - France - - - Research Organisations - Research Organisations - - Supercapacitors are of great interest as energy storage systems because they exhibit very high rates of charge/discharge, long cycle lifes, and they are made of cheap and light materials. These attractive properties arise from - the electrostatic nature of the charge storage which results from ion adsorption in the electrode pores. Recently, it was demonstrated that ions can enter pores of sub-nanometer sizes leading to a huge increase of capacitance. This was an important - breakthrough as the energy density of supercapacitors, relatively low compared to batteries, is what currently limits their application. - - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - SuPERPORES - - - ERC-2016-STG - - - 714581 - - - - - INSTITUT CURIE - INSTITUT CURIE - - - EUR 1 498 750 - - - Characterisation of DNA Double-Strand Break Repair by Alternative End-Joining: Potential Targets for Cancer Therapy - - - EUR 1 498 750 - - - France - France - - - Research Organisations - Research Organisations - - DNA repair pathways evolved as an intricate network that senses DNA damage and resolves it in order to minimise genetic lesions and thus preventing tumour formation. Gaining in recognition the last few years, the alternative - end-joining (alt-EJ) DNA repair pathway was recently shown to be up-regulated and required for cancer cell viability in the absence of homologous recombination-mediated repair (HR). Despite this integral role, the alt-EJ repair pathway remains poorly - characterised in humans. As such, its molecular composition, regulation and crosstalk with HR and other repair pathways remain elusive. Additionally, the contribution of the alt-EJ pathway to tumour progression as well as the identification of a - mutational signature associated with the use of alt-EJ has not yet been investigated. Moreover, the clinical relevance of developing small-molecule inhibitors targeting players in the alt-EJ pathway, such as the polymerase Pol Theta (Polθ), is of - importance as current anticancer drug treatments have shown limited effectiveness in achieving cancer remission in patients with HR-deficient (HRD) tumours. - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - altEJrepair - - - ERC-2016-STG - - - 714162 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 183 454,80 - - - Bio-INspired GOld metamaterials - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The development of metamaterials has opened new opportunities for designing novel devices in the field of imaging, data storage and sensing. Although some progress has been achieved in in this emerging area, the fabrication of - nanoscale metamaterials with tailorable geometries still remains challenging. This proposal aims to develop a facile and scalable synthesis approach to gold metamaterials inspired by nature. The key novelty of the action is to use self-assembled - cellulose nanocrystals as templates to fabricate gold morphologies with chiral periodic organization. The goals of the action are (I) the isolation of cellulose nanocrystals from bulk celluloses and their co-assembly to highly organized CNC and - CNC/Au chiral scaffolds, (II) the post-treatment of such chiral films to achieve high porosity and excellent compatibility with gold precursors, (III) the development of a facile wet-chemical route to continuous gold morphologies exploiting the - self-assembly of cellulose nanocrystals, (VI) the optical characterization of CNC-templated gold structures. The cellulose-assisted synthesis of gold metamaterials has a potential to open a new pathway for fabrication of novel metamaterials and - potentially can become a breakthrough technique in metamaterial engineering. - - 2019-02-28, Grant Agreement terminated - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - BINGO - - - H2020-MSCA-IF-2016 - - - 743543 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 3 487 580 - - - Magnetic Fields and the Formation of New Worlds - - - EUR 3 487 580 - - - France - France - - - Research Organisations - Research Organisations - - Magnetic fields impact the formation of low-mass stars and their planets, and contribute to setting adequate conditions for life to appear. They control the amount of material and angular momentum from which stars and their - planets form and mature, and can save newborn close-in planets from falling into their host stars. Magnetic fields can also affect planets by eroding their atmospheres and limiting their habitability, while hampering at the same time their - detectability. Our understanding of these issues is however limited and critically needs observational guidance. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - France - - - NewWorlds - - - ERC-2016-ADG - - - 740651 - - - - - LUNDS UNIVERSITET - - - EUR 173 857,20 - - - Fiscal capacity and warfare in Europe and Latin America in the long nineteenth century (1789-1913). - - - EUR 173 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - This project seeks to contribute to understanding the impact of warfare on the expansion of fiscal capacity in the long nineteenth century (1789-1913) in Europe and Latin America. The relationship between late-modern warfare - and fiscal institutions has been a contested issue. Even though wars may exert a negative short-time impact on public revenues due to the physical destruction that they cause, several authors have suggested that over the long run they may promote - fiscal innovations that improve the government’s capacity to collect taxes. However, our knowledge about state-making and the rise of fiscal capacity in late modern times is still insufficient. To begin with, much more emphasis should be placed in - the effects exerted by limited and civil wars. Unlike mass warfare, limited and civil wars do not necessarily trigger the social and political changes associated to permanent increases of public revenues. Secondly, the interaction between warfare and - economic and political factors still remains open to question. - - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - WARCAP - - - H2020-MSCA-IF-2016 - - - 752163 - - - - - DOUGLAS CONNECT GMBH - JOHANNES GUTENBERG-UNIVERSITAT MAINZ - FUNDACIO CENTRE DE REGULACIO GENOMICA - UNIVERSITEIT MAASTRICHT - THE UNIVERSITY OF BIRMINGHAM - NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - UPPSALA UNIVERSITET - MEDIZINISCHE UNIVERSITAT INNSBRUCK - INFORMATICS MATTERS LIMITED - INSTITUT NATIONAL DE L ENVIRONNEMENT ET DES RISQUES INERIS - STICHTING VU - - - EUR 2 999 112,50 - - - OpenRiskNet: Open e-Infrastructure to Support Data Sharing, Knowledge Integration and in silico Analysis and Modelling in Risk Assessment - - - EUR 2 999 112,50 - - - Switzerland - Germany - Spain - Netherlands - United Kingdom - Greece - Germany - Sweden - Austria - United Kingdom - France - Netherlands - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - - Toxicology and risk assessment are undergoing a paradigm shift, from a phenomenological to a mechanistic discipline based on in vitro and in silico approaches that represent an important alternative to classical animal testing - applied to the evaluation of chronic and systemic toxicity risks. Large databases and highly sophisticated methods, algorithms and tools are available for different tasks such as hazard prediction, toxicokinetics, and in vitro – in vivo - extrapolations to support this transition. However, since these services are developed independently and provided by different groups world-wide, there is no standardized way how to access the data or run modelling workflows. To overcome the - fragmentation of data and tools, OpenRiskNet will provide open e-Infrastructure resources and services to a variety of communities requiring chemical risk assessment, including chemicals, cosmetic ingredients, therapeutic agents, and nanomaterials. - OpenRiskNet will combine the achievements from earlier projects for generating modeling and validation workflows, knowledge integration and data management as well as include all ongoing projects and important stakeholders through an associated - partner programme. The main components of the infrastructure will be an interoperability layer added to every service to describe the functionality and guaranteeing technical and semantic interoperability, a discovery service, deployment options - based on container technology, and packaging of the infrastructure into virtual instances. This will be complemented by training and support on integration of specific services based on prototype implementation, usage of standard file formats for - data sharing including the generation of templates for data and metadata, as well as the harmonized usage of ontologies. Case studies will demonstrate the applicability of the infrastructure in productive settings supporting research and innovation - in safer product design and risk assessment. - - 2019-11-30, ongoing project - - - 2016-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.3."> - - - EINFRA-22-2016 - User-driven e-infrastructure innovation - - - RIA - Research and Innovation action - - - Switzerland - - - OpenRiskNet - - - H2020-EINFRA-2016-1 - - - 731075 - - - - - KAROLINSKA INSTITUTET - KAROLINSKA INSTITUTET - - - EUR 1 923 262,50 - - - Cellular Position Tracking Using DNA Origami Barcodes - - - EUR 1 923 262,50 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The research I propose here will provide an enabling technology; spatially resolved transcriptomics, to address important problems in cell- and developmental-biology, in particular: How are stem cells in the skin and gut - proliferating without turning into cancers? How are differentiated cells related, in their transcriptome and spatial positions, to their progenitors? - - 2022-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Sweden - - - CellTrack - - - ERC-2016-COG - - - 724872 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 183 454,80 - - - The dynamics and rheology of self-assembled empty liquids: from patchy toy models to anisotropic realistic systems - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - In this project I plan to investigate by means of numerical simulations the dynamics and rheology of low-density equilibrium gels made of limited-valence building blocks. I will start with simple toy models of patchy particles - and then add complexity in the form of inner degrees of freedom by investigating systems that undergo a hierarchical self-assembly process. Examples of such systems are recently synthesised DNA constructs and telechelic star polymers. The novelty of - DELTAS lies in the focus put on the role of the internal flexibility as a tool to tune the dynamics and the rheology of equilibrium gels. Indeed, the possibility of fine-tuning the structure of these materials lend themselves well to many - applications, ranging from medicine to material science. The project goes one step further by proposing to investigate the kinetics, dynamics and mechanical properties of these systems in the framework of (flexible) patchy systems. The usage of - simple toy models will grant a better understanding of the phenomenology of these systems. In addition, the realistic systems I plan to investigate will, on one hand, establish a stronger link between theory and numerical simulations and experiments - and, on the other hand, provide a testing ground for the results obtained with toy models. - - 2018-03-31, Grant Agreement terminated - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - DELTAS - - - H2020-MSCA-IF-2015 - - - 702298 - - - - - ERASMUS UNIVERSITEIT ROTTERDAM - - - EUR 177 598,80 - - - Monetary Spaces and hierarchies in Europe. Impact of Complementary Currencies - - - EUR 177 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - This research seeks to measure and analyse the social and economic impact of selected Community Currencies in Europe with the use of a self-assessment Total Quality Management model called Common Assessment Framework. - Complementary Currencies (CC) are a type of money designed to circulate alongside the Central Bank’s money to address objectives that the conventional money system does not. CC are tied to a specific demarcated community (i.e. locality, mutual-credit - networks, sectoral vouchers). The Common Assessment Framework (CAF) engages the organisation and its beneficiaries and performs a study of its structure and operation at a particular point in time and place. - - 2018-08-31, Grant Agreement terminated - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - MICCO - - - H2020-MSCA-IF-2015 - - - 704759 - - - - - FCIENCIAS.ID - ASSOCIACAO PARA A INVESTIGACAO E DESENVOLVIMENTO DE CIENCIAS - FCIENCIAS.ID - ASSOCIACAO PARA A INVESTIGACAO E DESENVOLVIMENTO DE CIENCIAS - - - EUR 1 231 319 - - - The Medieval and Early Modern Nautical Chart: Birth, Evolution and Use - - - EUR 1 231 319 - - - Portugal - Portugal - - - Research Organisations - Research Organisations - - Of all the technical and scientific developments that made possible the early modern maritime expansion, the nautical chart is perhaps the least studied and understood. This fact is very surprising as it was through those - charts that the newly discovered world was first shown to the amazed eyes of the European nations. Although the History of Cartography is a well-established academic discipline and old charts have been examined for many years, their detailed - technical study is still in its infancy. What is the origin of the pre-Mercator nautical chart, how charts evolved technically over time and how they were used at sea are all critical questions that remain to be answered. I intend to approach these - challenges in a truly interdisciplinary way, by using innovative and powerful tools as a complement to the traditional methods of historical research: analytical cartometric methods, numerical modelling and the examination of the manuscripts through - special lighting. By applying these tools to a large sample of charts of various periods and origins, I aim to unveil hidden graphic content related to their construction and use, to characterize their main geometric features, to establish meaningful - connections with contemporary navigational methods and exploration missions, and to numerically simulate their construction by taking into account the explanations given in the textual sources. The effectiveness of those techniques has already been - demonstrated in my previous studies, such as in the solution of an historical enigma which had been alive for more than a century: the construction of the Mercator projection, in 1569. Now, I propose to handle a broader and more complex set of - questions, which has eluded the historians of cartography for even a longer period. The clarification of these issues will have a ground-breaking impact, not only in the strict field of the History of Cartography, but also in the context of the - intellectual history at large. - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Portugal - - - MEDEA-CHART - - - ERC-2016-STG - - - 714033 - - - - - UNIVERSITY OF LEEDS - - - EUR 183 454,80 - - - The Bacteroides dual-pumping membrane-integral pyrophosphatase: a novel drug target - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Membrane-integral pyrophosphatases (M-PPases) couple cleavage of pyrophosphatase to pumping of ions across a membrane to generate membrane potential and play an important role in resistance to stressors. The solved structures - of an H+-pumping M-PPase from Vigna radiata and an Na+-pumping M-PPase from Thermotoga maritima show M-PPases form a channel through the membrane, and this channel is plugged by an ion gate formed by three charged residues. Despite these structures, - there are still many outstanding questions regarding M-PPases, especially in relation to H+ and Na+ dual-pumping M-PPases. - - 2017-05-31, Grant Agreement terminated - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - BactoDrug - - - H2020-MSCA-IF-2014 - - - 659677 - - - - - UNIVERSITAT WIEN - - - EUR 166 156,80 - - - Development of Maximum Efficiency Phase Contrast Electron Microscopy - - - EUR 166 156,80 - - - Austria - - - Higher or Secondary Education Establishments - - Electron microscopy is a key technique for imaging and analysis of materials. Although aberration correction has made atomic resolution possible at low accelerating voltages, beam damage remains a critical limitation for many - types of materials. The imaging modes currently in use today are inefficient in terms of the number of transmitted electrons detected and the way in which these are used to derive information. Current detectors integrate over details in the angular - distribution of scattered intensities, and make use of only a limited range of scattering angles. In the case of scanning transmission electron microscopy (STEM), a wealth of information is contained in the distribution of electron scattering as a - function of the illuminating probe position. The proposed work will make use of pixelated detectors to record this four-dimensional data set and develop methods to intelligently utilize the information it contains. This research project has become - possible through recent advances in the sensitivity and speed of pixelated detectors, and offers a new path to maximize the information gained per fast electron. Maximum efficiency phase contrast imaging in STEM recovers the full amplitude and phase - components of the specimen, with minimum dose, and maximum signal to noise ratio, and maximum contrast that does not require aberrations. In materials science for example it will enable imaging of charge transfer at point defects and interfaces while - simultaneous Z-contrast imaging provides interpretability and chemical sensitivity. Similarly, such high sensitivity phase detection will allow the direct imaging of local electric and magnetic fields at the highest possible spatial resolutions, - providing many new opportunities for understanding electronic, spintronic and magnetic materials at the heart of today’s technological advances. In biology, maximum efficiency phase contrast imaging may open the door to the ultimate low dose - molecular- and bio-imaging. - - 2017-06-30, Grant Agreement terminated - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Austria - - - DIGIPHASE - - - H2020-MSCA-IF-2014 - - - 655760 - - - - - FUNDACIO INSTITUT DE CIENCIES FOTONIQUES - - - EUR 158 121,60 - - - Exploring Photon-photon Interactions with Cold Rydberg Atoms - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - "The requirements for the basic building blocks of Quantum Information Processing (QIP) are sometimes contradictory: one must seek components that are immune to interactions to preserve their fragile quantum properties, and, - at the same time, to have strong, controllable interactions to perform operations on the quantum information they carry. - - 2017-08-31, Grant Agreement terminated - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - EPICA - - - H2020-MSCA-IF-2014 - - - 658258 - - - - - THE UNIVERSITY OF BIRMINGHAM - - - EUR 195 454,80 - - - Scanning probe energy loss spectroscopy of Nanoscale Alloy Particles for heterogeneous CATalysis - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Most heterogeneous catalysts take the form of catalytically active nanoparticles dispersed over a support medium. To improve catalytic function and reduce waste, researchers are increasingly seeking to improve the homogeneity - of these nanoparticles, whether it be their size, shape or composition. One of the difficulties facing researchers is that the techniques used to obtain quantitative information are typically averaged over ensembles of billions of nanoparticles. - Measurements of individual clusters require access to expensive instrumentation such as a scanning transmission electron microscope (STEM). The proposed research will apply scanning probe energy loss spectroscopy (SPELS) to study the composition, - size and shape of individual size-selected Pt-based binary alloy nanoparticles for fuel cell applications, deposited using an inert gas-aggregation source. In SPELS, a STM tip is used as a highly localised source of field-emitted electrons to - stimulate surface excitations such as plasmons. The energy of inelastically backscattered electrons from the surface is analysed with a spectrometer, so that spectroscopic mapping of the surface can be obtained as the tip is rastered across the - surface. This comparatively low-cost method is capable of producing a spatial resolution of 1-10 nm, so that the composition of individual nanoparticles can be sampled. SPELS will be used, in conjunction with STM, to study the composition and surface - structure of bimetallic clusters before and after reaction. This data will be correlated with data on the reactivity of the clusters, probed by CO temperature programmed desorption measurements. These measurements will be used to tailor nanoparticle - composition and improve homogeneity, resulting in more efficient catalysts. - - 2018-04-30, Grant Agreement terminated | - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SNAPCAT - - - H2020-MSCA-IF-2015 - - - 703864 - - - - - UNIVERSITEIT MAASTRICHT - - - EUR 177 598,80 - - - Affective neurocognitive model for the ‘Uncanny Valley’ - - - EUR 177 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - The Uncanny Valley hypothesis (UV), proposed already 45 years ago, suggests that too humanlike robots or other artificial characters will elicit feelings of eeriness (Jpn. ‘bukimi’) in human observers. Existing psychological - and neuroimaging studies have focused on the humanlikeness dimension of UV but neglected its emotional experience, which was at the heart of the original hypothesis. This interdisciplinary project will develop a thorough model for the emotional - dimension of UV, consisting both of subjective verbal descriptions and observed neuronal activation patterns. A series of neuroimaging experiments will be carried out at the Brain and Emotion Laboratory of Maastricht University (UM): the first - experiment will test the neuronal correlates of negative emotions elicited by semi-realistic virtual characters, and the second experiment will take a step beyond the original UV hypothesis by comparing the neuronal activation patterns of real and - virtual emotional expressions. A self-report questionnaire for verbalizing the emotional experience of UV will be developed during a secondment period at Eindhoven University of Technology (Tu/e). By explicating the emotional experience of UV and by - providing open tools for both research and industry, this project will be an important turning point for the future development of all humanlike technologies. Consistently, direct and concrete contacts with the animation industry are planned during - the project. My supervisor Prof. de Gelder from UM is one of the thought leaders in the field of affective cognitive neuroscience, and my secondment supervisor Prof. Ijsselsteijn from Tu/e is renowned for his work in human-technology interaction. I - am an experienced researcher with a dual background in both of these disciplines, as well as specific background in UV topic. This interdisciplinary synergy will maximize this project’s impact on the European society and help establish my position as - a leading independent scientist. - - 2018-07-31, ongoing project - - - 2016-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - NEUROBUKIMI - - - H2020-MSCA-IF-2015 - - - 703493 - - - - - VILNIAUS UNIVERSITETAS - - - EUR 130 779,60 - - - High throughput screening of single-cells using droplet microfluidics - - - EUR 130 779,60 - - - Lithuania - - - Higher or Secondary Education Establishments - - Tackling heterogeneous cell populations at single-cell resolution is becoming increasingly important in different branches of biology and biomedicine. Many useful techniques have been developed to profile and even selectively - purify single-cells, however, the demand for techniques with better analytical performance and improved high-throughput capabilities, remains very high. Droplet microfluidics can fulfill this demand by bringing higher throughput, scalability and - single molecule resolution that are hard to achieve with conventional technologies. In this project, a droplet microfluidics platform will be developed and applied for ultra-high-throughput single-cell screening and sequencing. The project will be - focused on B-cells that produce therapeutic antibodies or biomolecules of industrial interest. Cell compartmentalization into microfluidic droplets together with capture beads and barcoded DNA primers will enable a direct establishment of the linkage - between the genotype (genes or mRNA) and phenotype (binding, regulatory or activity of secreted proteins). The proposed work will allow the quantitative high-throughput antibody phenotyping without loosing the original heavy-light chain pairing, a - significant advantage over other technologies. Like no other system available to-date this the technological approach outlined in this proposal will provide a unique way to identify the primary sequence of heavy and light IgG genes encoding - functional monoclonal antibodies directly from single-cells, without a need to perform gene cloning or cell immortalization. The results of this work are likely to bring a significant impact not only in applied biological sciences but also in - biotechnology and biomedicine. - - 2018-03-20, Grant Agreement terminated | - - - 2016-03-21 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Lithuania - - - Cells-in-drops - - - H2020-MSCA-IF-2015 - - - 705791 - - - - - VRIJE UNIVERSITEIT BRUSSEL - UNIVERSITA DEGLI STUDI DI PADOVA - IMEDICA SA - ARTIA NANO - ENGINEERING & CONSULTING IKE - INOCURE SRO - - - EUR 864 000 - - - Enhanced brown adipose tissue activity using nanotechnology approaches - - - EUR 864 000 - - - Belgium - Italy - Romania - Greece - Czech Republic - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The use of nanotechnology and nano-materials in biological applications is being widely explored and is considered a valuable approach to ameliorate human wellbeing. Specifically, nanoparticles and carbon nanotubes are of - great scientific interest as they are currently used clinically as delivery systems for a wide range of drugs. An interdisciplinary approach that considers knowledge in chemistry, nano-materials, toxicology, physiology, molecular biology is vital for - the progress of these devices and for the development of new procedures to create a novel market-ready prototype to boost human metabolism, fighting obesity and cardio-metabolic disease. An inter-sectoral approach is also required to put together - Academic’s technical capabilities and facilities to conduct R&D activities with SMEs’ business expertise and viable supply chain to develop the prototype post project and to exploit the product in the market. Therefore, two academic (VUB and - UniPD) and three industrial (INOC, IMED, ARTIA) European participants will create an interdisciplinary and inter-sectoral co-operation (nanoBAT) to design and construct a novel nanostructured delivery-L-menthol system prototype for brown adipose - tissue activation. During its four years duration, nanoBAT aims to achieve research and innovation objectives via staff exchanges of experienced and early-stage researchers throughout a series of activities like: networking, research and training, - workshop, innovation, dissemination, and outreach. - - 2020-01-31, ongoing project - - - 2016-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Belgium - - - nanoBAT - - - H2020-MSCA-RISE-2015 - - - 691061 - - - - - TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY - UNIVERSITAET ST. GALLEN - STICHTING KATHOLIEKE UNIVERSITEIT BRABANT - BABSON COLLEGE - PEPPERDINE UNIVERSITY - - - EUR 180 000 - - - A knowledge transfer and sharing action for developing A new integrative approach to mitigating errors in hospitals: Resolving tensions in error research - - - EUR 337 500 - - - Israel - Switzerland - Netherlands - United States - United States - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Errors are a recurring fact of organizational life and the wisdom of managing and learning from errors is incontrovertible. In particular, medical errors in the health care industry, defined as avoidable adverse outcomes or - injuries to patients stemming from healthcare processes, pose serious threats to human life and have an impact on total national costs. Yet, healthcare organizations that achieve a breakthrough in mitigating errors are extraordinarily rare. The aim - of this Marie Skłodowska-Curie Actions proposal is thus to improve our understanding of the occurrence of medical errors and to develop a new, integrative approach to mitigating medical errors and promoting quality, efficiency, and innovativeness in - hospitals. We strive for this goal by immersing ourselves in broad literature reviews and going beyond state of the art, collecting massive first-hand data in the hospital settings, and testing our working hypotheses on both qualitative and - quantitative data. We envision three direct outcomes of our endeavor that are beneficial to both the academic community and heath care organizations. First, we will suggest an integrative theory of errors in organizations by identifying - discrepancies, tensional issues, and opportunities for research synthesis via level of analysis and temporal and priority lenses. Second, we will develop an innovative, hybrid method to illuminate the errors phenomena and assess long-term effects of - medical errors. Third, starting with the partnership between three participating research teams, we will create a long-lasting network that offers a rich resource for collaboration and knowledge-sharing that makes this resource more visible, - inspectable, and systematic, which may aid the process of learning at a larger societal level. - - 2018-12-31, Grant Agreement terminated - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Israel - - - Errspitals - - - H2020-MSCA-RISE-2015 - - - 690959 - - - - - UNIVERSITEIT MAASTRICHT - - - EUR 177 598,80 - - - Reducing Early Atrophy with Leucine during Immobilization of Skeletal Muscle - - - EUR 177 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Recovery from injury, illness, and/or disease is associated with skeletal muscle disuse. Muscle disuse leads to a loss of muscle mass, strength, and functional independence, and represents a “catabolic crisis” for the elderly - who are already at a greater risk for low muscle mass and strength due to age-related sarcopenia. Muscle mass is determined by the balance between muscle protein synthesis (MPS) and muscle protein breakdown (MPB). When MPB exceeds MPS, the result is - a negative net protein balance and muscle loss. Decreased MPS rates occur following the onset of immobilization-induced disuse, but there is no information on the response of MPB. mRNA and protein expression data indicate that the early stages of - disuse (0-5 days) result in activation of the ubiquitin proteasome system, and presumably MPB suggesting that the initial stages of disuse represent a critical period to intervene with appropriate countermeasures to attenuate the loss of muscle mass - and strength. Leucine is a key amino acid in the regulation of muscle protein metabolism that has been shown to inhibit MPB. The current proposal REALISM will 1) identify whether MPB is elevated during the early stages (72 hours) of - immobilization-induced disuse, 2) determine whether leucine can reduce MPB and the loss of muscle mass during the early stages of immobilization, and 3) determine whether leucine can preserve muscle mass and strength in the elderly during more - prolonged periods of immobilization. REALISM will identify the mechanisms underlying disuse atrophy in response to immobilization and examine potential therapeutic strategies to offset the loss of muscle mass and strength. The M3 laboratory of Dr. - van Loon at Maastricht University (UM) offers the most ideal environment for me to conduct REALISM, and take a major step towards the achievement of my career goal of setting up my own research program and establishing myself as an independent - scientist. - - 2017-04-30, closed project | - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - REALISM - - - H2020-MSCA-IF-2014 - - - 659739 - - - - - INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE - - - EUR 246 668,40 - - - Reaching the roots of systemic nitrogen (N) signaling in plants - - - EUR 246 668,40 - - - France - - - Research Organisations - - The survival of multicellular organisms requires inter-organ communication via long-distance signals. This is especially relevant in plants where post-embryonic development can be altered in response to sensing a heterogeneous - nutrient environment in the soil. For example, a long-distance, inter-organ “root-shoot-root” relay system enables plant roots to specifically forage for nitrate-rich patches in a heterogeneous nutrient soil environment . In this proposal, I will use - a unique “split-root” system to uncover the mechanisms of this systemic “root-shoot-root” relay system. Specifically, I will identify the targets of systemic N-signaling in plants as well as the potential RNA signals that traffic in phloem cells, the - “information highway” to enable this inter-organ communication in plants. I will identify RNAs (mRNAs and smRNAs) associated with inter-organ signaling using a combination of time-based modeling and validate candidate genes using transgenics and - shoot-root grafting. These studies will be the among the first to uncover systemic N-signals in a multicellular eukaryote. - - 2018-08-31, ongoing project | - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - France - - - Nitro Systems - - - H2020-MSCA-IF-2014 - - - 659592 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - POTSDAM INSTITUT FUER KLIMAFOLGENFORSCHUNG - JOHANNES GUTENBERG-UNIVERSITAT MAINZ - RUHR-UNIVERSITAET BOCHUM - UNIVERSITY OF WAIKATO - - - EUR 144 000 - - - QUantitative paleoEnvironments from SpeleoThems - - - EUR 229 500 - - - United Kingdom - Germany - Germany - Germany - New Zealand - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Speleothems (cave deposits, e.g. stalagmites) represent unique terrestrial archives that allow for accurately dated, high-resolution (often annual), continuous and long (many millennia) climate reconstructions. Such records - are vital for understanding how climate varies and how our environments respond on seasonal to millennial timescales. However, current speleothem studies can only make qualitative inferences about climate parameters – i.e. they can tell us the - direction of change (warmer, drier, etc.) but not the amount of change (how warm? how dry?). Quantitative information is crucial to make speleothem-based data more useful to climate modellers and policy makers. - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - United Kingdom - - - QUEST - - - H2020-MSCA-RISE-2015 - - - 691037 - - - - - UNIVERSITEIT MAASTRICHT - - - EUR 177 598,80 - - - Towards Guaranteeing the Right to Effective Assistance of Defence Counsel in Member States in Trans-border Criminal Cases - - - EUR 177 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - The right to effective assistance of defence counsel (READC) is one of the fundamental features of fair trial. In the context of open borders and increasing number of trans-border criminal cases it is important that all EU - Member States (MS) guarantee the READC to suspects and requested persons in European arrest warrant cases at least on a minimum level. The Strasbourg system is no designed to achieve this goal, so the EU has taken the initiative via the Directive - 2013/48/EU on the right of access to a lawyer in criminal proceedings etc. (22 Oct 2013). Considering the imminent transposition date of 27 Nov 2016, this project aims at determining how the MS are progressing in implementing the Directive. As the - Directive not only guarantees the READC, but also requires that in case of breach of the READC, the MS have to ensure effective remedies, the final goal of the project is to propose remedies for trans-border cases that could be common to all MS. The - research activities will be performed in the international environment of the Maastricht University, a centre of expertise on research on the READC in Europe, and will consist of two parts. - - - 2017-12-31, closed project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - Netherlands - - - ToEfDeCo - - - H2020-MSCA-IF-2014 - - - 654261 - - - - - INSTITUT DE PHYSIQUE DU GLOBE DE PARIS - - - EUR 173 076 - - - 3D Full Waveform Inversion on seismic data at the East Pacific Rise - - - EUR 173 076 - - - France - - - Higher or Secondary Education Establishments - - The mid-ocean ridge system is the longest volcanic mountain chain that wraps around the Globe along which two plates have been separating and oceanic crust has been forming by highly active magmatic processes operating within - and at the base of thus formed crust. It is believed that there is a strong link between these magmatic processes known at large spatial scales (1-100 km) and relatively localized (0.001-1 km) tectonic/ volcanic/hydrothermal/biological processes, and - their expression onto the seafloor. However, the characteristics of the link are largely unknown. The origin of the most of the unknowns is embedded in poorly defined properties of the upper crust (its structure, P and S wave velocities, porosity, - density, anisotropy, etc.), where the link is hosted and its activity is taking place. - - - 2017-08-31, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - 3DWISE - - - H2020-MSCA-IF-2014 - - - 655283 - - - - - UNIVERSITEIT MAASTRICHT - - - EUR 177 598,80 - - - Time of damage in classic galactosemia: is prenatal toxicity a determinant factor? - - - EUR 177 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - The TIME project aims to ascertain the time at which the toxicity observed in classic galactosemia begins, particularly if it begins prenatally. Recent advances in the molecular bases of classic galactosemia have taken - research a step further towards therapy development. Therefore, it is of utmost importance to elucidate when the damage accurately begins, in order to define the time at which therapy should be initiated so that it can effectively prevent the - development of long-term complications. - - 2018-01-31, closed project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - TIME - - - H2020-MSCA-IF-2014 - - - 658967 - - - - - UNIVERSITY OF GLASGOW - - - EUR 195 454,80 - - - The role of amphidial drug uptake in the mode of action and resistance to ivermectin in nematodes of livestock - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The macrocyclic lactones such as ivermectin are the cornerstone for the treatment of key nematode infections of livestock, crops and man. Resistance to many of these broad-spectrum anthelmintics is becoming commonplace, while - new classes of active compounds are increasingly difficult to find, threatening food supplies and public heatlh worldwide. The exact molecular and biochemical mechanisms of resistance, particularly to the widely used macrocyclic lactone class, are - still poorly understood, impeding the development of efficient strategies to control drug resistance. I hypothesize that the amphidial sensory organs of nematodes are the major route of macrocyclic lactone drug uptake and that mutations in this - uptake mechanism represents the primary source of drug resistance. In the first phase of the project, I will develop laboratory methods for testing amphid function in two parasitic nematodes of veterinary significance, the trichostrongyles Haemonchus - contortus and Teladorsagia circumcincta. These techniques will be applied on drug resistant and sensitive isolates to evaluate the role of amphids in ivermectin uptake. In the second phase, I will use the C. elegans model to generate mutants - resistant to three major classes of anthelmintic drugs, ivermectin, the benzimidazole albendazole and the imidazothiazole levamisole. I will then apply genomic tools to identify alleles responsible of this multi-drug resistance phenotype. This - project aims to understand the link between amphid defects, anthelmintic drug uptake, and development of resistance, and will generate a thorough knowledge of this unexplored and apparently widespread resistance mechanism in nematodes. These results - will also pave the way to the implementation of a fast and reliable measurement of drug resistance in the field. On the whole, the project will bring a direct contribution to current veterinary and public health challenges by suggesting new - strategies to limit the emergence of drug resistance. - - 2019-08-31, Grant Agreement terminated - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - IDRAM - - - H2020-MSCA-IF-2016 - - - 747676 - - - - - UNIVERSITEIT MAASTRICHT - - - EUR 177 598,80 - - - Macrophage proliferation and ontogeny in murine models of atherosclerosis - - - EUR 177 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Atherosclerosis is a slowly progressing inflammatory disease that underlies some of the most common causes of death in western society. The central role of macrophages throughout its pathogenesis makes this cell an eminent - target for therapeutic intervention. Recent studies have subverted the classical view that atherosclerotic plaque macrophages mainly originate from recruited circulating monocytes, launching the new notion that macrophages could also be derived from - clonal expansion of resident macrophages or even trans-differentiated vascular smooth muscle cells. The relative importance of these mechanisms to the pathogenesis remains however unclear, due to a lack of adequate animal models that allow assessing - this question. - - 2018-01-31, closed project - - - 2016-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - Athero MPh proliferation - - - H2020-MSCA-IF-2014 - - - 661099 - - - - - PROVINCIA LOMBARDO VENETA - ORDINEOSPEDALIERO DI SAN GIOVANNI DI DIO- FATEBENEFRATELLI - - - EUR 180 277,20 - - - Electrophysiological markers of cognitive processes and neuroplasticity in healthy ageing and Alzheimer`s disease - - - EUR 180 277,20 - - - Italy - - - Research Organisations - - Ageing of the European population is increasing prevalence of age-related diseases such as Alzheimer’s disease (AD). AD is considered a public health priority due to socio-economic costs and limited efficacy of current - pharmacological treatments. Co-registration of electroencephalogram (EEG) and transcranial magnetic stimulation (TMS) is a novelty, non-expensive and non-invasive approach to obtain surrogate markers of cognitive decline. Moreover, repetitive TMS - (rTMS) is considered a promising tool to induce neuroplasticity and improve cognitive functions. The main objective of this research is providing markers of brain activity, reactivity, connectivity and plasticity related with healthy and pathological - ageing (i.e., early AD). Thus, samples of healthy young, healthy elderly and AD patients will perform a behavioural task (to study visuospatial attention and cognitive control processes) while carrying out EEG recording and online EEG/TMS - co-registration. Correlates of brain activity (event-related brain potentials), reactivity (amplitude of TMS evoked potential -TEP) and connectivity (TEP topography, coherence, synchronization, and graph theoretical analysis of complex networks) will - be obtained before and after of delivering offline rTMS. It will allow studying differences in cortical responses induced by rTMS on each group of participants, which will provide correlates and biomarkers of brain plasticity related with age and AD. - These biomarkers will allow the identification of individuals at early stages of AD and evaluating efficacy of novel TMS treatments. Importantly, identification of rTMS parameters responsible to induce neural plasticity and improve cognitive - functions will contribute to develop rehabilitation protocols for AD patients. - - 2017-10-31, closed project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - NIBSAD - - - H2020-MSCA-IF-2014 - - - 655423 - - - - - UNIVERSITEIT MAASTRICHT - UNIVERSITEIT MAASTRICHT - - - EUR 150 000 - - - Silencing miR-199b to attenuate the progression of heart failure. - - - EUR 150 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Cardiac hypertrophy is the principal risk factor for the development of heart failure and lethal arrhythmias. A complex web of interconnected signalling pathways has been implicated in hypertrophy and species of non-coding RNA - molecules, microRNAs, have been shown to regulate these pathways. The recognition of microRNAs as potential therapeutic targets marks the principal step towards new therapeutic concepts. The SIRENE project represents the advancement of the - therapeutic strength of miRNA silencing in clinically relevant heart failure models towards a valuable proposition for counteracting pathological hypertrophic signalling and heart failure development. In specific, during the related ERC CALMIRS - project, it was found that sustained knockdown of endogenous miR-199b in the adult mouse heart in vivo leads to profound protective effects against symptoms of heart failure. Therefore, a new class of RNA antagonists, targeting miRNAs is powerful and - holds great promise to become the next generation therapeutics. At this stage the newly developed antagonists are unique in their affinity and specificity for miR-199b and current data demonstrates a profound rescue by miR-199b antagonists on heart - failure symptoms such as pressure overload induced cardiac morphological, histological, functional and molecular abnormalities in mice. The challenge of the SIRENE project is to identify immediate and longer term opportunities for commercialisation - with high clinical and commercial feasibility. Therefore different business models will be studied in terms of market research, IP strategy and business development to eventually consolidate a commercial strategy and business case for presenting our - business proposition to strategic partners or venture capitalists. Simultaneously, dose-range finding and efficacy studies will be conducted in rats, a clinically relevant and larger animal model of heart failure, for further preclinical development. - - 2017-02-28, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2014 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Netherlands - - - SIRENE - - - ERC-2014-PoC - - - 665647 - - - - - UNIVERSITEIT MAASTRICHT - - - EUR 165 598,80 - - - MicroRNAs as therapeutic targets for ARVC. - - - EUR 165 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - ARVC is a hereditary disease mainly characterised by the progressive substitution of the myocardium with fatty or fibro-fatty tissue involving predominantly the right ventricle. Clinically, ARVC shows wide variation between - individuals. Together with modifier genes, common sequence variants, and environmental as well as endogenous factors, epigenetic modifiers such as miRNAs are hypothesized to be potential targets for disadvantageous environmental stimuli and may lead - to the onset of complex and heterogeneous diseases such as ARVC. The main research objective of this EF is to assess and validate the relevance of disease mechanisms underlying the development of ARVC and to identify novel RNA-based targets in mouse - models and ARVC patients. The EF programme comprises two tightly linked components – research and complementary training - that will be complemented with secondments in two (non-) academic organisations active in the field of molecular cardiology. - The host organisations are strongly committed to enhancing the creative and innovative potential of the ER who wishes to diversify her individual competence in terms of skill acquisition to become a successful European scientist. - - 2017-07-31, closed project | - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - MIRAGE - - - H2020-MSCA-IF-2014 - - - 660440 - - - - - UNIVERSITEIT MAASTRICHT - - - EUR 165 598,80 - - - Mechanism Design under Incomplete Information - - - EUR 165 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - The purpose of this project is to study mechanism design under incomplete information with an emphasis on the design of voting procedures. Mechanism design is the commonly used term for the design of games with a certain - objective. For instance, an auctioneer may wish to design an auction with the purpose of maximizing his own revenue. The usual assumption is that the mechanism designer does not know the preferences of the players, but the players do have this - information. In this project, the latter assumption is dropped. For instance, in national elections voters have a tendency to vote strategically, and in general only have limited information about the preferences of the other voters. In that case, - the objective of mechanism designer (designer of the voting system) is to elicit as much as possible the true votes (preferences), knowing that the voters have beliefs but no complete information about the preferences of the other voters. - Specifically, the project will concentrate on three issues: how does correlation between the voters’ beliefs effect the result of voting and how should the voting system be designed in order to elicit the true votes under this assumption of - correlation; can we improve on the results of the first issue by allowing for probabilistic mechanisms, i.e., involve chance; and, following up on this, if truthful voting is out of reach, can we at least get the truthful voting result as an - equilibrium outcome. The project is theoretical in nature but can lead to the design of experiments in particular testing the role of belief formation in voting. Further, the results of the project may lead to the design of improved smaller and - larger scale voting procedures. - - 2017-08-31, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - MEDINI - - - H2020-MSCA-IF-2014 - - - 660341 - - - - - UNIVERSITEIT MAASTRICHT - - - EUR 165 598,80 - - - Audiovisual Speech Segmentation and Oscillations - - - EUR 165 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Daily social tasks (e.g. meetings, shopping) rely on human communication with speech. Auditory only studies established that continuous speech segmentation relies on the temporal integration of rhythmic acoustic features - occurring at delta-theta rates in the signal, via a possible mechanism of entrainment coupled with beta activity. In terms of neural correlates, the timing network (including the basal ganglia, supplementary motor area and cerebellum) may actively - contribute to the temporal integration of auditory signal during continuous speech segmentation. However, speech is often multimodal and listeners need to integrate speaker’s body movements aligned to rhythmic acoustic features. Consequently, AV - speech may generate different rhythmic patterns than auditory only speech. How the brain translates naturally concomitant AV rhythms to facilitate speech segmentation clearly remains to be addressed. The goal of this project is to investigate the - oscillatory patterns and neural correlates of AV rhythms resulting from the temporal integration of body movements and salient acoustic features in speech. In a first EEG experiment, I will compare the modulations of delta-theta entrainment and - coupling with beta activity, depending on the relationship between visual and auditory information (congruent, incongruent and auditory only). Secondly, in an fMRI version of the experiment, I will explore the contribution of the timing network - during AV speech segmentation, and its different patterns of activations across speech conditions. Finally, to test whether the brain areas revealed by fMRI have a necessary role for the successful AV speech segmentation, I will run the same fMRI - experiment with Parkinson’s disease patients with dysfunctional basal ganglia. Looking at the timing network patterns of activations will also reveal if correlated body information eventually help PD to compensate basal ganglia deficit with greater - contribution of alternative path (i.e. cerebellum). - - 2018-05-01, ongoing project - - - 2016-05-02 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - AVISSO - - - H2020-MSCA-IF-2015 - - - 707727 - - - - - RUHR-UNIVERSITAET BOCHUM - RUHR-UNIVERSITAET BOCHUM - BAYERISCHE JULIUS-MAXIMILIANS UNIVERSITAT WURZBURG - - - EUR 1 500 000 - - - Tailoring Ylidic Compounds as Ligands for Organometallic Chemistry - - - EUR 1 500 000 - - - Germany - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Lewis bases are a fundamental class of compounds that are of utmost importance in almost any chemical transformation. According to the HSAB concept, they determine important properties such as the stability or solubility of - compounds or the selectivity of reactions. Yet, Lewis bases are used far beyond simple acid-base pairs. In coordination chemistry they act as efficient σ-donor ligands, which crucially affect the electronics of the metal and thus its reactivity. - Additionally, bulky Lewis bases as part of Frustrated Lewis Pairs are applicable in bond activation reactions and also in catalysis. Typical Lewis bases are neutral compounds with a free pair of electrons, such as amines or phosphines. In contrast, - carbon-centred Lewis bases such as carbenes have long been underestimated due to their usually high reactivity and sensitivity. Yet, the last decades have revealed a revolution in this context. Carbenes in particular have proven to be powerful - reagents not only as ligands, but also in organocatalysis and bond activation chemistry. Bisylides and their dianionic congeners (methandiides) with formally two electron pairs at carbon are further classes of carbon bases that have started to find - applications, but which are still profoundly underdeveloped. - - - 2021-06-30, ongoing project - - - 2016-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - YlideLigands - - - ERC-2015-STG - - - 677749 - - - - - INSTITUT DE PHYSIQUE DU GLOBE DE PARIS - - - EUR 173 076 - - - Life in Arsenic rich environments: a challenge or an opportunity? - - - EUR 173 076 - - - France - - - Higher or Secondary Education Establishments - - Arsenic is a notorious toxin, and as such may have exerted a strong selective pressure on the distribution and evolution of life on Earth. Despite evidence supporting the high levels and prominent role of As on the primitive - Earth, the essentiality and toxicity of As, and its impact on evolutionary processes remains unexplored. AsLife aims at taking a novel approach to assessing microbial As cycling by exploiting two linked «environments». The first are the microbial - mats from High-Altitude Andean Lakes, where it is known that As concentrations are far above background levels. Specifically, living and diagenetically-modified microbial mats will be investigated using scanning hard X-ray nanoprobes emerging at - synchrotron facilities. This non-invasive and non-destructive technique provides data on a sub-micrometer scale by which to tie physiological inference from trace metal(loid)s distribution and speciation patterns directly to the microfossil biomass. - Thus, providing a means to understand the interplay between microbial metabolisms and bio-availability of trace metal(loid)s in living and fossil ecosystems. The second environment comprises laboratory cultures, using the sampling power of «adaptive - laboratory evolution» to explore how microbes adapt and enhance As detoxification facing the extreme As levels present in Andean Lakes. These results will be discussed in light of genomic studies of As-rich microbiota performed by Argentinian - colleagues. - - - 2018-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - AsLife - - - H2020-MSCA-IF-2015 - - - 701662 - - - - - UNIVERSITY COLLEGE LONDON - - - EUR 195 454,80 - - - Investigation and modification of atypical dynamic brain activity underlying perceptual inflexibility of autism spectrum disorders - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Perceptual and cognitive inflexibility is considered to underlie the repetitive and restricted behaviours of autism spectrum disorder (ASD). However, despite its severe effects on daily life of autistic individuals, the - biological basis of these ASD core symptoms remain little known. In this project, I will investigate the neural mechanisms behind this fundamental mental inflexibility of ASD by examining neural activity during bistable perception, which is thought - to be suitable for evaluation of such mental and perceptual rigidity. To detect neural responses from the brains of autistic individuals during such fluctuating perceptual experience, I will empirically calculate the energy landscape of brain - activity from non-invasive measurements of brain activity and numerically simulate activity transition on the energy surface. Given the explanatory power of this method demonstrated by my preliminary data, this project is expected to provide the - first empirical evidence for autistic impairments in dynamic brain activity that underlies the mental inflexibility of ASD. Furthermore, successful completion of this main project will provide insight for a novel non-invasive intervention protocol to - mitigate such autistic cognitive rigidity, which will be subsequently tested within this research project. I believe that this project has the potential to provide a novel integrative perspective to understand autistic cognitive inflexibility and - presents a promising approach to modify these relatively overlooked symptoms. - - 2017-04-30, closed project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - AutismRigidPercept - - - H2020-MSCA-IF-2014 - - - 656161 - - - - - UNIVERSITEIT MAASTRICHT - UNIVERSITEIT MAASTRICHT - - - EUR 1 361 507 - - - The birth of the digital doctor? A comparative anthropology of medical techno-perception - - - EUR 1 361 507 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Digital technologies are reconfiguring medical practices in ways we still don’t understand. This research project seeks to examine the impact of the digital in medicine by studying the role of pedagogical technologies in how - doctors learn the skills of their profession. It focuses on the centuries-old skill of physical examination; a sensing of the body, through the body. Increasingly medical students are learning these skills away from the bedside, through videos, - simulated models and in laboratories. My research team will interrogate how learning with these technologies impacts on how doctors learn to sense bodies. Through the rich case of doctors-in-training the study addresses a key challenge in social - scientific scholarship regarding how technologies, particularly those digital and virtual, are implicated in bodily, sensory knowing of the world. Our research takes a historically-attuned comparative anthropology approach, advancing the social study - of medicine and medical education research in three new directions. First, a team of three ethnographers will attend to both spectacular and mundane technologies in medical education, recognising that everyday learning situations are filled with - technologies old and new. Second, it offers the first comparative social study of medical education with fieldwork in three materially and culturally different settings in Western and Eastern Europe, and West Africa. Finally, the study brings - historical and ethnographic research of technologies closer together, with a historian conducting oral histories and archival research at each site. Findings will have impact in the social sciences and education research by advancing understanding of - how the digital and other technologies are implicated in skills learning. The study will develop novel digital-sensory methodologies and boldly, a new theory of techno-perception. These academic contributions will have practical relevance by - improving the training of doctors in digital times. - - 2021-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - DigitalDoctors - - - ERC-2015-STG - - - 678390 - - - - - INSTITUT DE PHYSIQUE DU GLOBE DE PARIS - INSTITUT DE PHYSIQUE DU GLOBE DE PARIS - - - EUR 1 487 500 - - - High precision isotopic measurements of heavy elements in extra-terrestrial materials: origin and age of the solar system volatile element depletion - - - EUR 1 487 500 - - - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - "The objectives of this proposal, PRISTINE (high PRecision ISotopic measurements of heavy elements in extra-Terrestrial materials: origIN and age of the solar system volatile Element depletion), are to develop new cutting edge - high precision isotopic measurements to understand the origin of the Earth, Moon and solar system volatile elements and link their relative depletion in the different planets to their formation mechanism. In addition, the understanding of the origin - of the volatile elements will have direct consequences for the understanding of the origin of the Earth’s water. To that end, we will approach the problem from two angles: 1) Develop and use novel stable isotope systems for volatile elements (e.g. - Zn, Ga, Cu, and Rb) in terrestrial, lunar and meteoritic materials to constrain the origin of solar system’s volatile element depletion 2) Determine the age of the volatile element depletion by using a novel and original approach: calculate the - original Rb/Sr ratio of the Solar Nebula by measuring the isotopic composition of the Sun with respect to Sr via the isotopic composition of solar wind implanted in lunar soil grains. - - 2020-03-31, ongoing project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - PRISTINE - - - ERC-2014-STG - - - 637503 - - - - - THE ROYAL VETERINARY COLLEGE - THE ROYAL VETERINARY COLLEGE - - - EUR 2 498 718,76 - - - Testing the locomotor superiority hypothesis for early dinosaurs - - - EUR 2 498 718,76 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - I seek to unify evolutionary and biomechanical research by achieving a “functional synthesis” in evolution that causally links phenotypes (anatomy) to actual performance. Did early, bipedal dinosaurs evolve advantages in their - locomotor performance over other Late Triassic archosaurs (“ruling reptiles”)? This “locomotor superiority” hypothesis was first proposed to explain what made dinosaurs distinct from other Triassic taxa, perhaps aiding their survival into the - Jurassic. However, the hypothesis remains untested or unfairly dismissed. I will test this question for the first time, but first I need to develop the best tools to do so. - - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - DAWNDINOS - - - ERC-2015-AdG - - - 695517 - - - - - RUHR-UNIVERSITAET BOCHUM - RUHR-UNIVERSITAET BOCHUM - - - EUR 2 498 286 - - - Exploring and Preventing Cryptographic Hardware Backdoors: Protecting the Internet of Things against Next-Generation Attacks - - - EUR 2 498 286 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The digital landscape is currently undergoing an evolution towards the Internet of Things. The IoT comes with a dramatically increased threat potential, as attacks can endanger human life and can lead to a massive loss of - privacy of (European) citizens. A particular dangerous class of attacks manipulates the cryptographic algorithms in the underlying hardware. Backdoors in the cryptography of IoT devices can lead to system-wide loss of security. This proposal has the - ambitious goal to comprehensively understand and counter low-level backdoor attacks. The required research consists of two major modules: - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - EPoCH - - - ERC-2015-AdG - - - 695022 - - - - - UNIVERSITEIT MAASTRICHT - UNIVERSITEIT MAASTRICHT - - - EUR 1 500 000 - - - Imaging Brain Circuits to Decode Brain Computations: Multimodal Multiscale Imaging of Cortical Microcircuits to Model Predictive Coding in Human Vision - - - EUR 1 500 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The human brain is one of the largest and most complex biological networks known to exist. The architecture of its circuits, and therefore the computational basis of human cognition, remains largely unknown. The central aim of - this proposal is to image human cortical connectivity at multiple spatial scales in order to understand human cortical computations. - - - 2020-05-31, ongoing project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - MULTICONNECT - - - ERC-2014-STG - - - 639938 - - - - - UNIVERSITATEA DIN BUCURESTI - UNIVERSITATEA DIN BUCURESTI - FUNDATIA NOUA EUROPA - - - EUR 671 875 - - - Record-keeping, fiscal reform, and the rise of institutional accountability in late-medieval Savoy: a source-oriented approach - - - EUR 671 875 - - - Romania - Romania - Romania - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - The present research project focuses on an unjustly neglected corpus of late-medieval sources, the administrative and fiscal accounts (‘computi’) of the castellanies – basic administrative units – of the county of Savoy. I - propose a holistic model of analysis that can fully capitalise on the unusual wealth of detail of the Savoyard source material, in order to illuminate some key topics in late-medieval institutional and socio-economic history, from the development of - state institutions through administrative and fiscal reform – with particular attention to the transition from personal to institutional accountability – to the question of socio-economic growth, decline, and recovery during the turbulent period of - the late-thirteenth to the late-fourteenth century. More broadly, my research into these topics aims to contribute to our understanding of the late-medieval origins of European modernity. The advances of pragmatic literacy, record-keeping, and - auditing practices will be analysed with the aid of anthropological and social scientific theories of practice. By comparing the Savoyard ‘computi’ with their sources of inspiration, from the Anglo-Norman pipe rolls to the Catalan fiscal records, the - project aims to highlight the creative adaptation of imported administrative models, and thus to contribute to our knowledge of institutional transfers in European history. The project will develop an inclusive frame of analysis in which the - ‘computi’ will be read against the evidence from enfeoffment charters, castellany surveys (‘extente’), and the records of direct taxation (‘subsidia’). The serial data will be analysed by building a database; the findings of quantitative analysis - will be verified by case studies of the individuals and families (many from the middle social strata) that surface in the fiscal records. - - 2020-04-30, ongoing project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Romania - - - CASTELLANY ACCOUNTS - - - ERC-2014-STG - - - 638436 - - - - - RUHR-UNIVERSITAET BOCHUM - RUHR-UNIVERSITAET BOCHUM - - - EUR 1 394 040 - - - How and when was Japan settled by speakers of Japanese? Exploring the clues to Japanese prehistory preserved in old dialect divisions - - - EUR 1 394 040 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - It is thought that the Japanese language was brought to Japan in a series of west-to-east migrations from the Korean peninsula in prehistoric times. Through fieldwork on the tone systems of a cluster of outlying and not - sufficiently documented dialects in Japan (the so-called Gairin or ‘outer circle’ dialects), a genealogy of the members of this dialect group will be reconstructed. - - - 2021-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - JapPrehistMigration - - - ERC-2015-STG - - - 677317 - - - - - HUMBOLDT-UNIVERSITAET ZU BERLIN - - - EUR 159 460,80 - - - Physical Activities of Older Adults: Longitudinal Interdisciplinary Analysis - - - EUR 159 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - The PAOLInA-project focuses on physical activities of older citizens of European countries. It begins with the analysis of the phenomenon “physical activities”, and their change in the course of the late and latest years of - life. The goal is to show what is covered by the term “physical activities” (PAs), and to differentiate PAs into domains according to their purpose (e.g. sports in leisure time, PA for self-care, PA as form of transportation). The Experienced - Researcher (ER) hypothesizes that the overall involvement of older adults in PA does not necessarily decline as the individuals are getting older, but that some types of activities may even increase or replace others. If these interdependencies are - neglected in the measurement older adults may appear as more sedentary than they actually are. The ER will also examine the factors that influence the change of the PAs. She will look at the interplay between individual characteristics and the - attributes of people’s living environments. As a result, patterns of PA promoting factors will be carved out. The research will be based on secondary analysis of various longitudinal data sets, such as the German Socioeconomic Panel (SOEP) and the - Survey of Health and Retirement in Europe (SHARE). Multilevel modelling will be applied in the statistical analyses. Thus, the PAOLInA-project is innovative in several respects: It will differentiate the PAs, which – according to the state of the - existing research – has rarely been the case. It will reveal the long-term developments in older adults’ engagement and involvement in PAs. It will match individual characteristics with environmental and regional indicators. The ER will introduce her - perspective of health psychology into an institute that does not have this specialization yet. She will benefit from the excellent methodological expertise of her prospective supervisor, additional training and support from the partners, and get - access to a European network of collaborators. - - 2018-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - PAOLInA - - - H2020-MSCA-IF-2014 - - - 661555 - - - - - INSTITUT DE PHYSIQUE DU GLOBE DE PARIS - INSTITUT DE PHYSIQUE DU GLOBE DE PARIS - - - EUR 1 999 250 - - - Tracing ancient microbial cells embedded in silica - - - EUR 1 999 250 - - - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Reconstructing the nature and habitat of early life is a difficult task that strongly depends on the study of rare microfossils in the ancient rock record. The preservation of such organic structures critically depends on - rapid entombment in a mineral matrix. Throughout most of Earth’s history the oceans were silica-supersaturated, leading to precipitation of opal deposits that incorporated superbly preserved microbial cells. As we trace this record of life back in - deep time, however, three important obstacles are encountered; 1) microorganisms lack sufficient morphologic complexity to be easily distinguished from each other and from certain abiologic microstructures, 2) the ancient rock record has been - subjected to increased pressures and temperatures causing variable degradation of different types of microorganism, and 3) early habitats of life were dominated by hydrothermal processes that can generate abiologic organic microstructures. TRACES - will study the critical transformations that occur when representative groups of microorganisms are subjected to artificial silicification and thermal alteration. At incremental steps during these experiments the (sub)micron-scale changes in - structure and composition of organic cell walls are monitored. This will be compared with fossilized life in diagenetic hot spring sinters and metamorphosed Precambrian chert deposits. The combined work will lead to a dynamic model for microfossil - transformation in progressively altered silica-matrices. The critical question will be answered whether certain types of microorganisms are more likely to be preserved than others. In addition, the critical nano-scale structural differences will be - determined between abiologic artefacts – such as carbon coatings on botryoidal quartz or adsorbed carbon on silica biomorphs – and true microfossils in hydrothermal cherts. This will provide a solid scientific basis for tracing life in the oldest, - most altered part of the rock record. - - 2020-04-30, ongoing project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - France - - - TRACES - - - ERC-2014-CoG - - - 646894 - - - - - UNIVERSITEIT MAASTRICHT - UNIVERSITEIT MAASTRICHT - - - EUR 2 655 000 - - - Building complex life through self-organization: from organ to organism - - - EUR 2 655 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - A major challenge in regenerative medicine is to create phenotypic functioning tissues by controlling cell behaviour. We particularly lack the ability to form complex tissues composed of multiple cell types and with - three-dimensional architecture, which are defining features of most tissues. We know that cells are conferred with the ability to choreograph their own development through self-organization. I hypothesize that if we actively promote this intrinsic - capacity with new cell culture platforms, we can orchestrate self-organization to make complex tissues, organs, and even organisms with a high degree of reproducibility and in large numbers. - - - 2020-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Netherlands - - - ORCHESTRATE - - - ERC-2015-AdG - - - 694801 - - - - - THE HEBREW UNIVERSITY OF JERUSALEM - THE HEBREW UNIVERSITY OF JERUSALEM - NEW YORK UNIVERSITY - - - EUR 1 808 000 - - - Forecasting Surface Weather and Climate at One-Month Leads through Stratosphere-Troposphere Coupling - - - EUR 1 808 000 - - - Israel - Israel - United States - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Anomalies in surface temperatures, winds, and precipitation can significantly alter energy supply and demand, cause flooding, and cripple transportation networks. Better management of these impacts can be achieved by extending - the duration of reliable predictions of the atmospheric circulation. - - - 2021-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Israel - - - FORECASToneMONTH - - - ERC-2015-STG - - - 677756 - - - - - RUHR-UNIVERSITAET BOCHUM - RUHR-UNIVERSITAET BOCHUM - WEIZMANN INSTITUTE OF SCIENCE - - - EUR 2 500 000 - - - Time Resolved THz Calorimetry explores Molecular Recognition Processes - - - EUR 2 500 000 - - - Germany - Germany - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Time-resolved THz-Calorimetry Explores Molecular Recognition Processes - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - THZCALORIMETRY - - - ERC-2015-AdG - - - 695437 - - - - - OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN - OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN - RUHR-UNIVERSITAET BOCHUM - - - EUR 1 498 452 - - - Transmission of Classical Scientific and Philosophical Literature from Greek into Syriac and Arabic - - - EUR 1 498 452 - - - Austria - Austria - Germany - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - - It is often taken for granted that the Greek-Arabic translation movement (8th-10th c.) that made the whole bulk of Classical Greek scientific and philosophical literature available in Arabic (and that was later handed over to - Europe in Latin translations) owes much to the preceding period in the history of transmission of this scientific and philosophical literature, namely translations into the Syriac language that were implemented by Aramaic-speaking Syriac Christians. - The problem of continuity between the two periods however has not been tackled thoroughly in scholarship and thus the actual impact of the Syriac translations on later methods of translation has so far not been measured and assessed. One feasible - solution to this problem in our understanding of the background to the Greek-Arabic translation movement is to implement a comprehensive comparison of Syriac and Arabic translations by means of lexicographical analysis. This project offers a research - tool capable of allowing this comparison. It will combine methods of online lexicography and of corpus linguistics with the aim of presenting in a systematic and rationalized way the lexical data from the entire corpus of Syriac scientific and - philosophical translations, comparing and analyzing its terminology and translation techniques, first, with the extant Greek originals and, secondly, with Arabic versions. The lexicographic database will be an effective instrument providing definite - data for the study of Syriac and Arabic translations and their close connections. It will reveal how the Syriac translations along with underlying methods and tools that were put to use for the first time ever by Syriac Christians eventually - determined the prosperity of the Islamic sciences. Fully endorsing a principle of open access the database creates a new instrument for a study of the history of the transmission of Greek scientific literature in Antiquity and the Middle Ages. - - 2021-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Austria - - - HUNAYNNET - - - ERC-2015-STG - - - 679083 - - - - - UNIVERSITEIT MAASTRICHT - UNIVERSITEIT MAASTRICHT - - - EUR 1 937 500 - - - Mobility trajectories of young lives: Life chances of transnational youths in Global South and North - - - EUR 1 937 500 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The objective of MO-TRAYL is to develop a better understanding of the relationship between migration and young people’s life-chances by studying youth’s mobility trajectories. How the life chances of youths, defined as their - educational performance, psychological well-being and transitions into adulthood, are impacted by migration are of relevance for European cities that are faced with a growing youth population with migrant background. At the same time, cities in the - Global South, where many migrants in Europe originate from, are faced with large portions of the population of minors who are living without at least one of their parents due to their parent’s migration. There is growing concern in both academia and - policy about how these ‘stay-behind’ children are faring. Yet little is known about how migration impacts young people in the Global North and South in the medium-term, in part because our conception of young people’s mobility patterns has to date - been overly simplified (either they move once, or they do not). This results in a lack of data that specifically looks at the different mobility patterns of young people and hardly any that has a longitudinal dimension. MO-TRAYL will break new ground - by studying simultaneously youths in the Global South who have remained ‘at home’ and those who have migrated to Europe by making use of unique new longitudinal data collected in the Global South as well as collecting new data in the Global North - that specifically traces the mobility trajectories, the resulting different family compositions along the way, and how both affect life chances. Through a transnational perspective in which family members and events spanning home and host countries - are brought to bear on life chances, MO-TRAYL aims to re-conceptualize youth mobility and families and add a longitudinal dimension to the study of migration and life chance outcomes. The project focuses on Ghanaian children in Ghana, The - Netherlands, Belgium and Germany. - - 2021-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - MO-TRAYL - - - ERC-2015-CoG - - - 682982 - - - - - INSTITUT DE PHYSIQUE DU GLOBE DE PARIS - - - EUR 185 076 - - - To understand the redox variations and interactions between hydro-, bio- and atmosphere: the power of bromine stable isotopes. - - - EUR 185 076 - - - France - - - Higher or Secondary Education Establishments - - The stable isotope geochemistry of chlorine (Cl) and bromine (Br) are considerably different. While most Cl isotope data are in the range from -1.21 to +0.40‰, Br isotope data are from -0.06 to +1.48‰. Interesting is that Br - isotope variations are of the same magnitude as Cl isotope variations. Also Br isotope values of ancient evaporites are very positive (+0.6‰), impossible to explain from oceans with a modern isotope composition. These data are unexpected considering - the small fractionation factors for Br compared to Cl. - - 2018-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - France - - - BRISOACTIONS - - - H2020-MSCA-IF-2015 - - - 702001 - - - - - THE UNIVERSITY OF HERTFORDSHIRE HIGHER EDUCATION CORPORATION - - - EUR 251 857,80 - - - Information Theoretic Evaluation of Random Content Generation in Games - - - EUR 251 857,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - INTERCOGAM’s goal is to develop and use information theory based intrinsic motivation formalisms to evaluate automatically generated game mechanics. Content generation is one of the production bottlenecks of professional game - design, which has begun to be addressed by procedural content generation. In this field, search based procedural content generation uses the idea of evolutionary algorithms to represent, modify and adapt games and game content to maximise fun and - engagement with the game. One major challenge here is the identification of widely applicable fitness functions, which capture the different aspects of what makes a game fun, such as challenge level, complexity, pacing, etc. INTERCOGAM will relate - psychological and game design concepts of game experience to either existing formalisms for intrinsic motivation or develop new ones, where appropriate. Human play testers will then play procedurally generated games and evaluate their own experience, - allowing us to verify whether our formalism captures the actual human motivation, and whether humans indeed act according to certain intrinsic motivations. INTERCOGAM will yield both, a tool to generate new and engaging game ideas, aiding better and - faster game design, and provide new insights into how the human mind engages with different worlds where there is no external reward present. - - 2019-11-30, ongoing project - - - 2016-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - INTERCOGAM - - - H2020-MSCA-IF-2015 - - - 705643 - - - - - THE ROYAL VETERINARY COLLEGE - - - EUR 183 454,80 - - - Evaluations of bone strength in the evolutionary invasion of land by tetrapods - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - How tetrapods (vertebrates with digit-bearing limbs) became terrestrial is one of the most transformative yet enigmatic events in vertebrate history that set the stage for the diversification of tetrapods thereafter. Being on - land imposes physical demands on the musculoskeletal system and weak bones can severely limit the capabilities of animals, yet the importance of bone strength in the evolution of terrestrial locomotion is not well understood. The proposed research - integrates innovative approaches on the limbs of an early stem tetrapod, Ichthyostega, in order to: 1) quantify how well the limb bones in an early stem tetrapod could support locomotion on land, 2) compare the differences between the fore- and - hindlimb bone mechanics, and 3) test the prevailing hypothesis that early stem tetrapods walked like extant salamanders. An interdisciplinary synthesis of cutting-edge techniques in engineering, 3D biomedical imaging, palaeontology, and biomechanics - will be used to test the structural integrity of fossil limb bones in silico. Bone strength will be quantified with high-resolution μ-CT scans and finite element analysis, an engineering approach to estimate stresses and deformations in complex - structures in response to physical demands. This novel dataset will address the ability of Ichthyostega to move on land, and what types of locomotor behaviours were not possible for an early stem tetrapod on land. Simultaneously, training and - research activities in state-of-the-art engineering and 3D technology, evolutionary biomechanics, and public outreach will foster the development of the Experienced Researcher (ER) into an innovative and broadly trained researcher and science - communicator. At a broader scale, tracing back the evolutionary steps to becoming terrestrial yields powerful insights into the tetrapod body plan, informing how ecological transitions influence functional innovation and how human anatomy is - influenced by our ancestry from aquatic tetrapods. - - 2018-08-21, ongoing project - - - 2016-08-22 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - TETRAPODBONES - - - H2020-MSCA-IF-2015 - - - 703516 - - - - - UNIVERSITEIT MAASTRICHT - UNIVERSITEIT MAASTRICHT - - - EUR 2 499 399 - - - Tackling the Achilles Heel of Immunotherapy: Validating imaging biomarkers and targeting the immunological niche of tumour hypoxia - - - EUR 2 499 399 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Lung cancer is the most common cause of death from cancer worldwide with 1.59 million deaths annually and it places the highest economic burden of all cancers on the EU at €18.8billion. These figures call for a major - transformation of the therapeutic management of lung cancer. The recent developments in immunotherapy give new hope. At present a significant minority of patients benefit from immune therapy, which remains not curative when delivered alone. It is - thus clear that improving the efficacy of immune therapy is needed as well as the identification of predictive biomarkers. Combining immunotherapy with radiotherapy improves effectiveness, but resistance is still common, most probably because of - hypoxia. In HYPOXIMMUNO, we will open up a new paradigm in treating metastatic NSCLC. I will provide for the first time (pre)clinical proof of concept of (i) highly innovative CT-based radiomics and PET-hypoxia imaging patient stratification tools - and (ii) a tri-modal curative hypoxia-targeting treatment strategy that complements current immunotherapy and radiotherapy approaches. This tri-modal curative treatment strategy is based on (1) high precision Stereotactic Radiotherapy (SABR) to kill - cancer cells and trigger the immune system, combined with (2) a hypoxia-activated prodrug to target the hypoxic tumour cells resistant to immunotherapy and (3) a promising and innovative tumour specific antibody (Ab)-based immunotherapy - (immunocytokine L19-IL2 to “push the accelerator” with or without a checkpoint inhibitor to “release the break”) to form a powerful synergistic immuno-oncology strategy. In HYPOXIMMUNO, I envision to lay the foundation for the next breakthrough in - oncology, by improving patient selection and developing highly innovative cancer therapies that target hypoxia, to improve the quality of life and prolong survival of cancer patients, in particular patients with metastatic NSCLC (watch the animation - summarising the project: https://youtu.be/oP9Gp4a0b_Q). - - 2021-11-30, ongoing project - - - 2016-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Netherlands - - - HYPOXIMMUNO - - - ERC-2015-AdG - - - 694812 - - - - - RUHR-UNIVERSITAET BOCHUM - RUHR-UNIVERSITAET BOCHUM - - - EUR 1 472 268,75 - - - Leveraging Binary Analysis to Secure the Internet of Things - - - EUR 1 472 268,75 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - We are in the midst of the shift towards the Internet of Things (IoT), where more and more (legacy) devices are connected to the Internet and communicate with each other. This paradigm shift brings new security challenges and - unfortunately many current security solutions are not applicable anymore, e.g., because of a lack of clear network boundaries or resource-constrained devices. However, security plays a central role: In addition to its classical function in protecting - against manipulation and fraud, it also enables novel applications and innovative business models. - - - 2020-02-29, ongoing project - - - 2015-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - BASTION - - - ERC-2014-STG - - - 640110 - - - - - RUHR-UNIVERSITAET BOCHUM - RUHR-UNIVERSITAET BOCHUM - - - EUR 1 497 916,26 - - - From Supramolecular Chemistry to Organocatalysis: Fundamental Studies on the Use of Little-Explored Non-Covalent Interactions in Organic Synthesis - - - EUR 1 497 916,26 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Hydrogen-bonds have found widespread use in various fields of chemistry, including supramolecular chemistry, organic chemistry, and more lately organocatalysis. Although a multitude of structurally different hydrogen-bond - donors has been developed, their mode of action is in all cases necessarily based on the same interacting atom, hydrogen. - - - 2020-04-30, ongoing project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - XBCBCAT - - - ERC-2014-STG - - - 638337 - - - - - INSTITUTE OF EXPERIMENTAL MEDICINE - HUNGARIAN ACADEMY OF SCIENCES - - - EUR 245 250 - - - Deciphering the cholinergic modulation of the hippocampal place code. - - - EUR 245 250 - - - Hungary - - - Research Organisations - - Acetylcholine released by cholinergic neurons in the basal forebrain is a critical component of the modulatory cocktail governing the emergence, stabilization and reorganization of cortical ensembles of co-active neurons - representing the environment. In the hippocampus, ACh renders the state of the network optimal for the acquisition of novel information. Deterioration of cholinergic modulation leads to severe deficits in hippocampal function manifested as - debilitating cognitive impairments. Despite decades of intense research fundamental questions are still open about the cholinergic modulation of hippocampal information processing: i) how is the behaviour-dependent firing of different neuron types - determined by ACh? ii) how does ACh contribute to the emergence of the spatially selective firing of principal cells, their amalgamation into sequences representing the surroundings of the animal and the storage of “relevant” sequences? iii) how does - ACh alter the place code in response to salient environmental stimuli? Technological breakthroughs of the past years have opened the possibilities of addressing these long-standing questions about cholinergic modulation. Thus, I aim to combine the - latest electrophysiological recording, optogenetic manipulation and behavioural tracking methods to monitor hippocampal neuronal ensembles in freely behaving mice while manipulating the cholinergic input of the hippocampus by light-responsive - microbial opsins. Results of the proposed research programme will decipher the role of ACh in hippocampal information processing and inform us how subcortical modulation contributes to the conversion of external inputs from the environment to - internal representations. By accomplishing the programme outlined in the proposal I will be acquainted with the cutting edge technologies as well as skills indispensable for starting my independent research group and expanding the research potential - of my home institute. - - 2019-08-07, ongoing project - - - 2016-08-08 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Hungary - - - HippAchoMod - - - H2020-MSCA-IF-2015 - - - 707359 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 212 463 - - - Operation Condor: Accountability for Transnational Crimes in Uruguay - - - EUR 212 463 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Confronting past atrocities is essential to consolidate democracy and human rights protection. Truth and justice initiatives investigating crimes perpetrated at the national level have long been occurring. Yet, accountability - for transnational crimes is a pending issue in scholarship and practice. - - - 2019-07-31, ongoing project - - - 2016-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - Operation Condor - - - H2020-MSCA-IF-2015 - - - 702004 - - - - - THE ROYAL VETERINARY COLLEGE - - - EUR 195 454,80 - - - Harnessing the power of bioinformatic analysis to improve genetic selection for fertility in dairy cows - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Genetic selection for high yielding dairy cows has been associated with reduced fertility. Infertility remains the major reason for culling, decreasing longevity and reducing production efficiency. We propose that this trend - could be reversed by identifying key genes involving reproductive function and selective breeding of more longlasting cows. The specific research objectives are: 1) to train the incoming researcher in bioinformatics methodologies related to analysis - of large genomic datasets including SNP detection, genotyping, and evolutionary conserved DNA elements detection; 2) to use the methodologies to analyse dairy phenotypic and genomic data to highlight potential genic and regulatory regions of the - cattle genome containing polymorphisms which are beneficial, with a particular focus on fertility; 3) to use appropriate tools to investigate the likely effects of both coding and regulatory variants on the expression of the candidate genes found in - these regions; 4) to use pathway analysis to understand how the candidate genes may influence key molecular events and larger gene networks involved in reproductive phenotypes; 5) to recommend appropriate selection procedures to the EU dairy breeding - industry to supplement current genomic methods. The project combines the expertise of Consiglio per la Ricerca in Agricoltura e l’analisi dell’Economia agraria, Italy (CREA) and the Royal Veterinary College, UK (RVC) in farm animal genetics and - genomics and dairy cow production. The objectives will be met by the mobility of Dr L Buggiotti to the UK, where she will work closely alongside two senior RVC scientists, Dr DM Larkin and Professor DC Wathes. She will transfer this expertise back to - CREA on her return. Both groups are experienced in knowledge transfer to the dairy industry and are committed to use the information generated to breed more fertile cows, so improving longevity and promoting sustainability of the EU dairy industry. - - 2018-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - United Kingdom - - - Bioinformatics4Breeding - - - H2020-MSCA-IF-2015 - - - 703376 - - - - - UNIVERSITEIT MAASTRICHT - - - EUR 174 864,60 - - - Connecting neuronal network activity with regional specificity for Alzheimer pathology: a multi-modal neuroimaging approach - - - EUR 174 864,60 - - - Netherlands - - - Higher or Secondary Education Establishments - - As the world’s population is aging, the prevalence of Alzheimer’s disease (AD) is estimated to triple by 2050. Even though AD was identified more than 100 years ago, research has gained momentum only the last 30 years. To - date, studies have mainly focused on the accumulation of two proteins, amyloid-beta and tau to understand the pathophysiology of this disease. In this project, I will take a new approach, by investigating the interaction between these two - pathological hallmarks of AD and neuronal activity as a potential causal model for AD. The underlying hypothesis is that regional levels of neuronal activity determine the interaction between amyloid and tau pathology, and lead to AD symptomatology. - To that end, I aim to combine novel molecular and state-of-the-art magnetic neuroimaging techniques with higher statistical modeling techniques. The group of Prof. Johnson at Massachusetts General Hospital (MGH) is currently the leading group pushing - these techniques forward. The expertise within the lab of Prof. Johnson, his extensive network, the skills that I will acquire throughout this fellowship (scientifically and management-wise), combined with my existing level of expertise in MRI and my - participation in diverse European networks will provide me with the competences to lead my own research group and establish a functional international multidisciplinary AD research network. Delaying or even treating this disease will require a - multifactorial, multidisciplinary approach in which researchers combine resources, data and results in a coordinated manner worldwide. The implementation of these techniques in Europe and the subsequent close collaborations between European and - American networks will have the highest chances to improve detection, prevention and treatment of AD. - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Netherlands - - - CONNECT - - - H2020-MSCA-IF-2015 - - - 706714 - - - - - INSTITUT CURIE - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSITY OF KEELE - UNIVERSITAET OSNABRUECK - RUHR-UNIVERSITAET BOCHUM - EFFICIENT INNOVATION SAS - - - EUR 3 473 026 - - - Hijacking cell signalling pathways with magnetic nanoactuators for remote-controlled stemcell therapies of neurodegenerative disorders - - - EUR 3 473 026 - - - France - France - United Kingdom - Germany - Germany - France - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Neurodegenerative diseases, such as Parkinson’s disease, are a major public health issue given the aging population in Europe and beyond. While curative pharmacological treatment of these diseases is not in sight, cell - replacement therapies (CTs) are considered very promising, in particular with the advent of stem-cell reprogramming technologies. However, a fundamental challenge in the medical application of CTs in the brain of patients lies in the lack of control - of cell behaviour at the site of transplantation, and particularly their differentiation and oriented growth. The aim of this project is to introduce a fundamentally new concept for remote control of cellular functions by means of magnetic - manipulation. The technology is based on magnetic nanoparticles functionalized with proteins involved in cellular signalling cascades. These biofunctionalized MNPs (bMNPs) will be delivered into target cells, where they act as intracellular - signalling platforms activatable in a spatially and temporally controlled manner by external magnetic fields. The project will focus on engineering these tools for the control of neuronal cell programming and fibre outgrowth by hijacking Wnt and - neurotrophin signalling, respectively, with the ulti-mate objective of advancing cell replacement therapies for PD using dopaminergic precursor neurons. - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-1-2014 - FET-Open research projects - - - RIA - Research and Innovation action - - - France - - - MAGNEURON - - - H2020-FETOPEN-2014-2015-RIA - - - 686841 - - - - - UNIVERSITEIT UTRECHT - - - EUR 260 929,80 - - - Towards the selective hydrodeoxygenation and hydrogenation of levoglucosenone using base metal heterogeneous catalysts modified by atomic layer deposition - - - EUR 260 929,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Catalytic technology has advanced markedly throughout the 20th century, refining the catalytic processes that provide us with fuels and base chemicals. Presently some important challenges in catalyst development are: - - 2020-06-14, ongoing project - - - 2017-06-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Netherlands - - - TAILORCAT - - - H2020-MSCA-IF-2015 - - - 701028 - - - - - UNIVERSITEIT MAASTRICHT - UNIVERSITEIT MAASTRICHT - - - EUR 1 500 000 - - - 3D Scaffolds as a Stem Cell Delivery System for Musculoskeletal Regenerative Medicine - - - EUR 1 500 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Aging worldwide population demands new solutions to permanently restore damaged tissues, thus reducing healthcare costs. Regenerative medicine offers alternative therapies for tissue repair. Although first clinical trials - revealed excellent initial response after implantation of these engineered tissues, long-term follow-ups demonstrated that degeneration and lack of integration with the surrounding tissues occur. Causes are related to insufficient cell-material - interactions and loss of cell potency when cultured in two-dimensional substrates, among others. - - 2020-04-30, ongoing project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - CELL HYBRIDGE - - - ERC-2014-STG - - - 637308 - - - - - STIFTUNG PREUSSISCHER KULTURBESITZ - STIFTUNG PREUSSISCHER KULTURBESITZ - - - EUR 1 500 000 - - - Localizing 4000 Years of Cultural History. Texts and Scripts from Elephantine Island in Egypt - - - EUR 1 500 000 - - - Germany - Germany - - - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - The aim of this project is to write a cultural history of 4000 years, localized on Elephantine Island in Egypt. Elephantine was a militarily and strategically very important island in the river Nile on the southern border of - Egypt. No other settlement in Egypt is so well attested over such a long period of time. Its inhabitants form a multi-ethnic, multicultural and multi-religious community that left us vast amounts of written sources detailing their everyday lives from - the Old Kingdom to beyond the Arab Conquest. Today, several thousand papyri and other manuscripts from Elephantine are scattered in more than 60 institutions across Europe and beyond. Their texts are written in different languages and scripts, - including Hieroglyphs, Hieratic, Demotic, Aramaic, Greek, Coptic and Arabic. 80% of these manuscripts are still unpublished and unstudied. The great challenge of this project is to use this material to answer three key questions covering: - - 2020-06-30, ongoing project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - ELEPHANTINE - - - ERC-2014-STG - - - 637692 - - - - - BSH ELECTRODOMESTICOS ESPANA SA - - - EUR 158 121,60 - - - New engineered surfaces for a better life - - - EUR 158 121,60 - - - Spain - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Surface anti-condensation and/or anti-biofouling (by surface wettability control) are very interesting and useful properties aimed by industry as they can offer more energy efficient, easy-cleanable or more hygienic products. - In the last years, new non-conventional techniques have been developed in order to provide those new functionalities by physical surface modification (avoiding chemical coatings or doping bulk materials). But up to the moment, a technology able to - respond to hard industrial requirements as home appliances (i.e. durability, severe boundary conditions, low cost) has not been achieved. - - 2017-04-30, closed project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - Spain - - - ENSUR4LIFE - - - H2020-MSCA-IF-2014 - - - 654963 - - - - - DUBLIN INSTITUTE FOR ADVANCED STUDIES - - - EUR 187 866 - - - Disclosing the Inner Gaseous Discs of Early Evolved Protostars - - - EUR 187 866 - - - Ireland - - - Higher or Secondary Education Establishments - - A first step towards understanding planetary formation is the characterisation of the structure and evolution of protoplanetary discs. Although the large scale disc is understood in some detail, very little is known about the - inner 5 au (i.e. within a radius corresponding to Jupiter's orbit) in which the main physical processes take place: accretion, ejection and planetary formation. For the nearest sites of star formation, this region is inaccessible to standalone - telescopes, and only recently optical/infrared interferometers have been able for the first time to spatially resolve it. - - - 2018-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Ireland - - - DIGDEEP - - - H2020-MSCA-IF-2015 - - - 706320 - - - - - UNIVERSITY OF KENT - - - EUR 195 454,80 - - - Human myosins - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - In utero development is critical for normal skeletal and cardiac muscle function throughout life. Many diseases, such as distal arthrogryposis (affecting 1/3000 live births) and clubfoot (1/1000) in skeletal muscle and - arrhythmias in cardiac muscle (1/4000), manifest in the embryonic and foetal period. They permanently affect longevity and quality of life. Because the effects of these diseases are present at birth, the study of in utero samples is essential to - understanding the diseases’ properties and effects on the developing muscle tissues. Additionally, many of these afflictions are caused by mutations in the isoforms of troponin or myosin II that are predominantly expressed during human development. - Studying the native muscle is all the more important as a control in furthering research on the effects of mutations in troponin and myosin. In particular, human foetal-specific isoforms of myosin II expressed in these muscle are poorly understood - and very little has been published about these isoforms. We do know from the literature that myosin’s use of its substrate, ATP, varies widely between isoforms and that the myosin expression changes during times of physiological distress, such as - heart failure. Because congenital abnormalities of the heart and skeletal muscle both can originate in the foetal muscle, further investigation is needed into the myosins’ biophysical and biomechanical mechanisms. The overarching goal of this project - is to improve understanding of how foetal forms of skeletal and cardiac myosins work and are regulated by troponin in muscle, using biophysical-biochemical, molecular biology and computational modelling techniques. The fellow will do this by - experimentally determining the kinetics of myosin-ATP, myosin-actin and myosin-actin-troponin-tropomyosin interactions using stopped-flow kinetic analysis, and then use the parameters defined to inform the computational models developed by Dr. - Geeves. - - 2017-05-31, closed project | - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - FCSM - - - H2020-MSCA-IF-2014 - - - 659534 - - - - - UNIVERSITA CA' FOSCARI VENEZIA - - - EUR 168 277,20 - - - “Thomas Aquinas’ Summa Theologiae Ia IIae translated by Demetrius Cydones and Bessarion’s incomplete Compendium of the translation – A Critical Editio Princeps” - - - EUR 168 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - The proposed Project is the critical edition (editio princeps) of the Greek translation of Thomas Aquinas’ Summa Theologiae Ia IIae by Demetrios Cydones and of its partial Compendium by Cardinal Bessarion. - - - 2018-10-02, ongoing project - - - 2016-10-03 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - TASTGCEP - - - H2020-MSCA-IF-2015 - - - 703595 - - - - - UNIVERSITEIT LEIDEN - - - EUR 242 929,80 - - - Perceptions of threat to personal values shape punishment judgments through social identity threat - - - EUR 242 929,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - In modern societies, the criminal justice system is entrusted to punish norm violators in a fair and impartial way. Yet, punishment judgments are subject to biases, and are sometimes shaped by extralegal factors, as - illustrated for example by the over-representation of African-Americans in inmates in the US. This project investigates one such factor, namely perceived threats to one’s personal values. We argue that even when unrelated to the wrongdoing, - value-violations represent a threat to one’s personal values and to one’s identity. As such, value-violations trigger a motivation to restore the threatened values and identity, leading to differential punishment judgments as a function of the - target’s fit or misfit with the perceiver’s values. We test this crucial role of perceptions of threat to personal values in two lines of research, using a combination of traditional experimental research methods, and modern measurement methods. In - the line of research A, we aim to identify moderators of the effect of personal value on punishment judgments. Experimentally increasing or removing threat to values will allow us to gain a clearer understanding of the causal processes at play. In - the line of research B, we aim to identify the neural processes underlying the effects of perceptions of threat to personal values on punishment judgments. Using fMRI, lesion patients and cardiovascular indices, we will gain complementary - perspectives on the dynamics at play. As a result, the present proposal will enhance knowledge in the fields of values, social justice and morality, but also offer applicable strategies to reduce the impact of threat to values on real-life - potentially consequential judgments, for example in the legal system. - - 2019-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Netherlands - - - ThreatValPun - - - H2020-MSCA-IF-2015 - - - 703401 - - - - - UNIVERSITEIT MAASTRICHT - - - EUR 177 598,80 - - - microRNAs in susceptibility to traumatic stress - - - EUR 177 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Traumatic stressors are important and prevalent risk factors for psychiatric disorders, such as post-traumatic stress disorder (PTSD). People differ strikingly in their susceptibility to develop PTSD after traumatic stress, - however the exact underlying biological mechanisms of differential susceptibility are unknown. The identification of biomarkers that distinguish between persons at high and low risk of developing PTSD following trauma exposure would enable more - effective preventive strategies and early interventions. Epigenetic mechanisms have been proposed to underlie the relationship between exposure to traumatic stress and the susceptibility to develop PTSD. Recent work carried out by the host laboratory - demonstrated that DNA methylation might regulate the impact of traumatic stress on gene expression and ultimately brain function. Based on this and the emerging role of miRNA as key epigenetic players in psychiatric disorders, I hypothesize that (i) - susceptibility to traumatic stress exposure is associated with distinct miRNAs expression profiles with blood-brain correlation, (ii) experimental manipulation of miRNA expression levels in animals alters their susceptibility to traumatic stress. - These hypotheses will be tested by a unique set of epigenetic epidemiological studies using prospective cohorts with longitudinal sampling schemes of military soldiers deployed to war, next to experimental animal studies. The proposed - multidisciplinary and translational project will open the possibility of tapping into the mechanisms underlying differential susceptibility to traumatic stress through blood profiling. It has excellent prospects for yielding clinically relevant and - usable biomarkers for the prediction of susceptibility to traumatic stressors. Moreover, the project will reinforce my foundation as a highly promising early career researcher by broadening my knowledge, skills, professional experience and network - necessary to launch my own research group. - - 2018-05-31, ongoing project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - TraumiR - - - H2020-MSCA-IF-2015 - - - 707362 - - - - - UNIVERSITEIT MAASTRICHT - - - EUR 165 598,80 - - - Enhancing expectancy formation in healthy aging through statistical and sensorimotor learning - - - EUR 165 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - My research examines how humans form new expectancies, or states of anticipation for future events, and how expectancy formation changes over the lifespan. Humans constantly anticipate upcoming events in order to understand - those events, prepare actions, and adapt to changes. Although the neural and behavioral signatures of expectancies have been well-characterized, we do not know how they arise and how they change over the lifespan. I aim to reveal the following: 1) - How new expectancies are formed during the course of learning novel information. 2) How expectancy formation differs between younger and older adults. 3) How the combination of regularities in event structure and sensorimotor integration, a - phenomenon that has not been investigated, potentiates expectancy formation. 4) The role of interacting subcortical-cortical neural networks in expectancy formation. I will monitor the dynamic changes in electrophysiological brain responses, as well - as overt anticipatory behaviour, over the course of learning in order to capture the changes of anticipatory responses online, and I will apply Bayesian neural network modelling to infer the neural and cognitive state changes underlying these - response changes. I will also measure changes in subcortical-cortical networks that result from learning, including structural integrity, functional connectivity, and the ability to decode the learned information. This multi-methods approach will - utilize my expertise in behavioural and MRI methods combined with my research group's expertise in EEG and computational modelling, as well as the state-of-the-art EEG, MRI, and laboratory facilities, on-site expertise, and support staff available at - Maastricht University. This research is urgently needed so that we can finally understand the origin of expectancies, their consequences on the aging brain, and how we can enhance their formation to improve lifelong learning. - - 2018-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - Expectancy learning - - - H2020-MSCA-IF-2015 - - - 707865 - - - - - THE ROYAL VETERINARY COLLEGE - - - EUR 251 857,80 - - - Network Analysis of Musculoskeletal Evolution and Modularity during the Fin-to-Limb Transition - - - EUR 251 857,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The fin-to-limb transition was a major milestone in the history of life that shaped the morphology and remarkable biodiversity of land vertebrates. A central question in vertebrate evolution is how the various anatomical parts - of limbs evolved semi-autonomously (modularity) while still growing and adapting in coordination (integration). The main goal of this project is to unravel (i) the evolutionary changes in modularity of the musculoskeletal system that occurred during - the evolution from fins to limbs and (ii) how these newly acquired modular organizations facilitated the evolution of different morphologies for the forelimb and hindlimb. To this end, we will evaluate the modularity of limbs and the strength of - topological integration among modules by using an innovative approach–anatomical network analysis–¬¬based on the topological relations that anatomical parts establish among them; these anatomical relations are embodied in network models and - quantified globally using sophisticated algorithms from Graph Theory. We propose a multidisciplinary combination, for the first time, of (i) new data on fin/limb muscle anatomy in extant species, (ii) reconstruction of muscle attachments in extinct - forms, and (iii) the use of innovative tools such as Anatomical Network Analysis to identify morphological modules and quantify their integration within a phylogenetic context. The results of this unique and transformative project have the potential - to revolutionize our understanding of limb evolution during the fin-limb transition. The training in gross anatomy, imaging techniques, and reconstruction of muscles in fossils by the leading researchers involved in this project will foster the - development of the candidate Fellow as an independent and innovative frontline researcher in theoretical, evolutionary, and comparative biology in the EU. - - 2018-08-14, ongoing project - - - 2015-08-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - LIMB NETWORKS - - - H2020-MSCA-IF-2014 - - - 654155 - - - - - ACADEMISCH ZIEKENHUIS GRONINGEN - - - EUR 196 380,90 - - - Moving from genome wide association to elucidating causal mechanisms of electrocardiographic traits - - - EUR 196 380,90 - - - Netherlands - - - Higher or Secondary Education Establishments - - Understanding how genes and genetic variants influence heart function is of major importance, not only from a basic science viewpoint, but also as a foundation for future innovation in medicine and health-care. In this - proposal, Dr. Niek Verweij aims to identify novel genes and mechanisms underlying heart growth. This will be done in collaboration with the top-scientist Dr. Chris Newton-Cheh (Harvard/Massachusetts General Hospital, Broad Institute of Harvard and - MIT) and Dr. Laurie Boyer (MIT). As heart growth accompanies many forms of heart disease, this project will focus on the QRS-complex (of the electrocardiogram) in population based studies as this reflects electrically active cardiac mass. We will - search for novel low-frequency genetic variants associated with the QRS-complex within the CHARGE consortium and within a Dutch population using dedicated reference panels. Loci will be interrogated through the use of published and unpublished in - silico big-data sets to further prioritize variants and regions for experimental follow-up aimed at elucidating biological mechanisms. This project will bridge the gap between population based genetic association studies (with Dr. Newton-Cheh) to - functional biology (with Dr. Laurie Boyer). This proposal will provide novel insights into cardiomyocyte functioning and provide novel avenues to study heart disease vulnerability and design innovative treatment. - - 2017-09-30, closed project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Netherlands - - - MOvE-ECG - - - H2020-MSCA-IF-2014 - - - 661395 - - - - - UNIVERSITE DES SCIENCES ET TECHNOLOGIES DE LILLE - LILLE I - RUHR-UNIVERSITAET BOCHUM - UNIVERSITATSKLINIKUM ERLANGEN - GOETEBORGS UNIVERSITET - LVIVSKYI NATIONALNYI MEDYCHNYI UNIVERSYTET IMENI DANYLA HALYTSKOHO - GRAPHENEA SA - LSO MEDICAL - RS ARASTIRMA EGITIM DANISMANLIK ILAC SANAYI TICARET LIMITED SIRKETI - - - EUR 580 500 - - - Pathogen and Graphene - - - EUR 580 500 - - - France - Germany - Germany - Sweden - Ukraine - Spain - France - Turkey - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Complications related to infectious diseases have significantly reduced, particularly in the developed countries, due to the availability and use of broad-range antibiotics and wide variety of antimicrobial agents. Excessive - use of antibiotics and antimicrobial agents increased significantly the number of multi-drug resistant (MDR) bacteria. This has resulted in a serious threat to public health. The inexorable rise in the incidence of antibiotic resistance in bacterial - pathogens, coupled with the low rate of emergence of new clinically useful antibiotics, has refocused attention on finding alternatives to overcome antimicrobial resistance. Novel strategies aiming to reduce the amount of antibiotics, but able to - prevent and treat animal and human infections should be investigated, evidenced and approved. Among the various approaches, the use of graphene and its derivatives is currently considered a highly promising strategy to overcome microbial drug - resistance. - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - France - - - PANG - - - H2020-MSCA-RISE-2015 - - - 690836 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - UNIVERSITAETSKLINIKUM ESSEN - UNIVERSITEIT MAASTRICHT - TECHNISCHE UNIVERSITAET DRESDEN - UNIVERSITE CATHOLIQUE DE LOUVAIN - INSTITUT CURIE - - - EUR 3 081 061,44 - - - Radiation Innovations for Therapy and Education - - - EUR 3 081 061,44 - - - United Kingdom - Germany - Netherlands - Germany - Belgium - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - Approximately 45-60% of all cancer patients are treated with radiotherapy. Some of these patients have a good outcome, but in other cases their illness fails to be cured. This may result from distant metastases or from - regrowth of the primary tumor. This training network is built on the premise that considerable advances in understanding radiobiology will open novel routes for effective therapeutic intervention with biological targets to improve the outcome of - cancer treatment; this progress requires a European-wide effort. - - - 2019-02-28, ongoing project | - - - 2015-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - RADIATE - - - H2020-MSCA-ITN-2014 - - - 642623 - - - - - UNIVERSITEIT MAASTRICHT - - - EUR 177 598,80 - - - Monitoring changes in brain states using dynamical causal networks - - - EUR 177 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - I propose a new model and estimation method that will allow Neuroscientists to detect, track, and predict temporal changes in dynamical brain networks non-invasively. These changes underpin shifts in brain (cognitive) states - which are currently inaccessible using standard Neuroimaging techniques. The method combines recent advances in dynamical systems theory and Bayesian inference to integrate Electroencephalography (EEG) and Diffusion Weighted Magnetic Resonance - Imaging (DWMRI) data in an efficient way. I will provide a proof of concept that the method can be used as a tool for early diagnosis of brain dysfunction. Given the current emphasis on reducing the social and economic impact of neurodegeneration and - aging across the EU, I focus on using Transcranial Magnetic Stimulation (TMS) to induce small changes in two exemplars of distributed networks that simulate semantic and motor neurodegeneration as a demonstration of what this method can detect. The - proposed approach has the potential to change strategies for screening and early diagnosis of neurodegenerative conditions. It will lead to new clinical applications that will significantly impact the study of the aging brain and mental health, as - well as the analysis of a wide variety of normal brain function, such as social behaviour, decision-making, or resting-state. - - 2018-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - DynamicBrainStates - - - H2020-MSCA-IF-2015 - - - 703211 - - - - - UNIVERSITY OF STRATHCLYDE - The Mental Health Foundation - SUOMEN MIELENTERVEYSSEURA RY - UNIVERSITAET ULM - - - EUR 477 000 - - - Citizenship, Recovery and Inclusive Society Partnership - - - EUR 477 000 - - - United Kingdom - United Kingdom - Finland - Germany - - - Higher or Secondary Education Establishments - Other - Other - Higher or Secondary Education Establishments - - People with mental health problems experience significant inequalities including high levels of early mortality, morbidity, unemployment, poverty, isolation and social exclusion. This also presents major health, social and - economic challenges to wider society. Our International Network unites leaders from academia, policy, practice, business and community organisations from the EU and US. Each partner has an impressive track record of leading evidence-based policy and - programme development at a national level and each has pioneered participation in research of people with lived experience of mental health problems. This transatlantic network will share and build upon state of the art knowledge in four key areas of - social inclusion: citizenship, recovery, stigma and public policy. Our collaboration will enable new knowledge, synergies and solutions to emerge by connecting our diverse national and disciplinary perspectives with the lived experiences of people - with mental health problems. Through the network we will enhance the skills and career opportunities for researchers and practitioners, and contribute towards the sustained inclusion of people with lived experience. This grant will enable us to share - our learning in profound ways to understand ‘what works’ in very different social contexts, including through interaction between the four themed work packages. There is a strong commitment amongst partners to maintain the network long term. As - partners we have considerable experience in supporting participatory mental health research with migrant citizens, people who are homeless and diverse ethnic minorities. Social exclusion is often intensified for women who encounter gender-based - discrimination and cumulative adversity. Therefore, throughout this proposal, we will pay particular attention to issues of intersectionality in relation to gender, and consider how promoting social inclusion, citizenship and rights must take account - of social identities. - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - United Kingdom - - - CRISP - - - H2020-MSCA-RISE-2015 - - - 690954 - - - - - UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - UNIVERSITAET BIELEFELD - ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOMATERIALES- CIC biomaGUNE - DIOMUNE SL - KEMIJSKI INSTITUT - ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOCIENCIAS - VIB - LOFARMA S.P.A. - UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II. - - - EUR 3 122 539,38 - - - Toll-Like Receptor 4 activation and function in diseases: an integrated chemical-biology approach. - - - EUR 3 122 539,38 - - - Italy - Spain - Germany - Spain - Spain - Slovenia - Spain - Belgium - Italy - Italy - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - Based on an international team derived from the COST action BM1003 (www.cost-bm1003.info, 2011-2014) and thus relying on consolidated group interactions and synergies and on a unique combination of chemistry, biology, - biophysics, biochemistry and pharmacology expertise, the TOLLerant project aims to gain information on molecular aspects of TLR4 activation and signaling by using synthetic and natural compounds and nanoparticles that interact selectively with some - components (mainly MD-2 and CD14) of the TRL4 recognition system. - - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Italy - - - TOLLerant - - - H2020-MSCA-ITN-2014 - - - 642157 - - - - - UNIVERSITEIT MAASTRICHT - - - EUR 260 929,80 - - - Chinese Heritage Tours and Adoptive Origin Stories: Towards a Transnational Adoptive Field - - - EUR 260 929,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - China became the largest source of adopted children worldwide since its Transnational Adoption Program in 1992.As adoptees are coming of age, some are interested in exploring their roots. Concurrently, as international - adoptions come under the scrutiny of critical groups in sending and receiving countries, heritage tours have become a popular way to satisfy the needs of different actors involved: from adoptive families seeking the youths’ roots to economically - minded tour operators and adoption agencies, to critical Western-based civil society groups who advocate psychological benefits for adoptees, such a resolution to their emotional befuddlement. Heritage tours are thus where transnational kinning - practices are played out, different notions of belonging intersect, and broader state and organizational interests meet. Thus, these tours constitute the ideal case for studying the transnational family-making process from a truly transnational - perspective. Through a detailed comparative study of how adopters and adoptees in Spain and the US-the countries with the largest number of Chinese adoptees-Chinese first parents, and Chinese and Western heritage tour agencies negotiate their - different interests, my research will facilitate one of the first multi-sited and multi-actor perspectives on transnational kinning practices through transnational adoption. The study brings together recent literature on transnational families and - transnational adoption and uses mixed methods from the social sciences and humanities to build a Transnational Adoptive Field approach intended to provide a comprehensive and cross-country comparative way to study transnational adoptive family-making - processes and involves ethnographic fieldwork in three different countries, interviews with key stakeholders and narrative analysis. In a wider sense, this inquiry is a case through which we may scrutinize the shifting meanings that re-define - familial and national belonging in today’s globalizing world - - 2019-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Netherlands - - - OriginStories - - - H2020-MSCA-IF-2014 - - - 660776 - - - - - HELMHOLTZ-ZENTRUM FUER INFEKTIONSFORSCHUNG GMBH - KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW - - - EUR 333 000 - - - Golden Mycological Triangle – joining forces to exploit mycological biodiversity for novel anti-infectives and other beneficial metabolites - - - EUR 333 000 - - - Germany - Netherlands - - - Research Organisations - Research Organisations - - The proposed project aims at the intensification of cooperations between research infrastructure organisations in German, the Netherlands and Thailand that are recognised internationally as strongholds in mycological, - biotechnological and microbiological research. The cooperation is intended to explore the mycological and microbiological biodiversity of Europe and Southeast Asia, in particular with regard to the search for the badly needed new antibiotics and - other biologically active substances. - - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Germany - - - GoMyTri - - - H2020-MSCA-RISE-2014 - - - 645701 - - - - - CITY UNIVERSITY OF LONDON - Biologicke centrum AV CR, v. v. i. - EOTVOS LORAND TUDOMANYEGYETEM - UNIVERSITA DEGLI STUDI DI TORINO - UNIVERSITEIT MAASTRICHT - - - EUR 216 000 - - - Conflict, Competition, Cooperation and Complexity: Using Evolutionary Game Theory to model realistic populations - - - EUR 243 000 - - - United Kingdom - Czech Republic - Hungary - Italy - Netherlands - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - "Real animals and human populations are complex, involving structural relationships depending upon space and time and varied interactions between potentially many individuals. Human societies feature family units, communities, - companies and nations. Some animal also have complex societies, such as primate groups and social insect colonies. Single organisms themselves can be thought of as complex ecosystems, host to many interacting life forms. - - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - United Kingdom - - - FourCmodelling - - - H2020-MSCA-RISE-2015 - - - 690817 - - - - - CONSORCI INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER - - - EUR 1 062 000 - - - Biomedicine international training research programme for excellent clinician-scientists - - - EUR 2 124 000 - - - Spain - - - Research Organisations - - Significant advances in clinical practice cannot be made without a thorough understanding of the disease mechanisms from laboratory benches combined with good clinical observation and knowledge of disease management from the bed side. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2016 - Co-funding of regional, national and international programmes - - - MSCA-COFUND-FP - Fellowship programmes - - - Spain - - - BITRECS - - - H2020-MSCA-COFUND-2016 - - - 754550 - - - - - RUHR-UNIVERSITAET BOCHUM - - - EUR 128 595,60 - - - Improving wet plastic recycling through innovative lagrangian particle-fluid simulations - - - EUR 128 595,60 - - - Germany - - - Higher or Secondary Education Establishments - - Wet particle separation is used widely in mineral processing as well as plastic recycling to separate mixtures of particulate materials into further usable fractions due to density differences. Despite its wide usage wet - particle separation processes are often attributed to operational problems especially if density differences of the feed material are low. A review of the state of the art clearly indicates that numerical modelling has not yet been applied to wet - separation processes due to the lack of applicable numerical schemes. On this background numerical modelling can strongly contribute towards improving the design and process parameters of wet particle separation technologies especially in the field - of plastic recycling - improvements have a strong environmental impact such as reduced landfill and lower overall pollution. - - 2016-11-30, closed project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - IMPRECSIM - - - H2020-MSCA-IF-2014 - - - 652862 - - - - - FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA - - - EUR 3 398 400 - - - MultIscale precision therapies for NeuroDEvelopmental Disorders - - - EUR 6 796 800 - - - Italy - - - Research Organisations - Chiara Andreoli - Tel.: +3901071781854 - Fax: +39 010 7170817 - - Neurodevelopmental disorders (NDD) represent an enormous burden for patients, their families, and society. Within EU, the incidence of autism spectrum disorders (ASD) is increasing to over 100 per 10,000 individuals. By - comparison, new cases of brain cancers in EU are estimated to be 10 per 10,000. Also, the requirement for lifelong care has a dramatic impact on healthcare costs, with an average lifelong cost per ASD patient of ~ 3.0 MEuro. - - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2016 - Co-funding of regional, national and international programmes - - - MSCA-COFUND-FP - Fellowship programmes - - - Italy - - - MINDED - - - H2020-MSCA-COFUND-2016 - - - 754490 - - - - - EIDGENOSSISCHE MATERIALPRUFUNGS- UND FORSCHUNGSANSTALT - - - EUR 3 540 000 - - - EMPAPOSTDOCS-II MSCA COFUND International, interdisciplinary, inter-sectoral PostDoc Fellowship Programme at Empa - - - EUR 7 080 000 - - - Switzerland - - - Higher or Secondary Education Establishments - - After successfully applying for a first postdoctoral fellowship programme in 2010, Empa has decided to create a second fellowship programme: It will allow 50 experienced researchers from all over the world to create a research - project and get the opportunity to work on their own research idea at one of the 30 research laboratories of Empa, in cooperation with a senior scientist of Empa of his/her choice. The training and mentoring scheme will ensure that the fellows not - only enhance their scientific experience but also acquire key long-life skills making them “contributing players” of the research community and society in general. As an interdisciplinary research institution within the Swiss ETH Domain, Empa, the - Swiss Federal Laboratories for Materials Science and Technology, conducts cutting-edge materials and technology research. Empa’s activities focus on meeting the requirements of industry and the needs of society, and thus link applications-oriented - research to the practical implementation of new ideas in the areas of nanostructured, “smart” materials and surfaces, environmental, energy and sustainable building technologies as well as biotechnology and medical technology. - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2016 - Co-funding of regional, national and international programmes - - - MSCA-COFUND-FP - Fellowship programmes - - - Switzerland - - - EMPAPOSTDOCS-II - - - H2020-MSCA-COFUND-2016 - - - 754364 - - - - - UNIVERSIDAD DE ALCALA - - - EUR 2 407 200 - - - GOT ENERGY TALENT. Attracting Talented Researchers within the Spanish Campus of International Excellence ‘Smart Energy’ and the region of Madrid. - - - EUR 4 814 400 - - - Spain - - - Higher or Secondary Education Establishments - - GOT ENERGY TALENT is a highly competitive, merit-based fellowship programme aimed at incorporating postdoctoral talent on the area of SMART ENERGY to enable them to conduct their own excellent research project and bringing it - closer to the society, in order to produce a positive effect not only in terms of excellent science and talent attraction but also by strengthening the regional economy and promoting international networking. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2016 - Co-funding of regional, national and international programmes - - - MSCA-COFUND-FP - Fellowship programmes - - - Spain - - - GOT ENERGY - - - H2020-MSCA-COFUND-2016 - - - 754382 - - - - - RUHR-UNIVERSITAET BOCHUM - KATHOLIEKE UNIVERSITEIT LEUVEN - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSITEIT UTRECHT - UNIVERSITEIT GENT - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - RUBOTHERM GMBH - Scientific Computing & Modelling N.V. - TECHNISCHE UNIVERSITAET MUENCHEN - TECHNISCHE UNIVERSITAET BERGAKADEMIE FREIBERG - - - EUR 3 804 639,48 - - - DEFect NETwork materials science and engineering - - - EUR 3 804 639,48 - - - Germany - Belgium - Spain - France - Netherlands - Belgium - United Kingdom - Germany - Netherlands - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Porous coordination network materials, also known as Metal-organic Frameworks (MOFs), are at the cutting edge of molecular materials science. DEFNET, “DEFect NETwork materials science and engineering”, is the first European - Training Network (ETN) at the intersection of chemistry, physics and engineering aimed at structural and functional complexity of MOFs. It provides a unique interdisciplinary training platform for early stage researchers and combines the expertise of - the academic and the non-academic sector for fundamental development and industrial application and technology transfer aspects. The research and the training program in materials synthesis, characterization, computational modelling and application - is accomplished in a coordinated effort involving 8 academic and 8 industrial partners from 6 European countries. DEFNET will particularly investigate defects, disorder and correlated phenomena in MOFs and related materials. The understanding and the - intentional modification of defect structures of porous coordination networks is essential for advanced controlling their properties in catalysis, gas capture and separation beyond existing materials limitations. Benchmarking will be done against - selected zeolite materials, which are very well established for large scale industrial applications. It is anticipated that superior functionalities of defect engineered MOFs will be identified which cannot be achieved by employing other porous - materials. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - DEFNET - - - H2020-MSCA-ITN-2014 - - - 641887 - - - - - HERIOT-WATT UNIVERSITY - - - EUR 183 454,80 - - - Novel braced frame for earthquake resilience - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The project will develop a seismic-resistant steel frame for high seismic resilience. The frame consists of a moment-resisting frame equipped with concentric braces. Replaceable energy-dissipative hourglass shape pins made of - duplex stainless steel that results in high post-yield stiffness are in series connected to the braces. Moreover, replaceable fuses are introduced at the locations of the beams of the moment resisting frame where plastic hinges are expected to - develop. The project uses an integrated experimental-numerical research methodology to evaluate the seismic performance of the proposed configuration. Emphasis is placed in developing a reliable seismic design methodology for the practical - application of the proposed system. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - CBF-EQRES - - - H2020-MSCA-IF-2016 - - - 748328 - - - - - UNIVERSITY COLLEGE LONDON - - - EUR 183 454,80 - - - GENOTYPE - ENDOPHENOTYPE ASSOCIATIONS IN PSYCHOSIS - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Psychotic disorders impose an increasing burden on the health of the European population, with an estimated five million affected individuals. As available drugs remain ineffective for 30% of the patients and come with many - secondary effects, there is urgent need to develop effective and safe therapeutic agents. Due to the high heritability of psychotic disorders, genetics shows great potential to inform the molecular mechanisms behind their pathogenesis. However, the - information we have gathered on psychosis genetics has not translated into improved therapeutics yet, due to, among other reasons, two big limitations: poor knowledge of the mechanisms behind the genetics – psychosis relation and high levels of - heterogeneity at the molecular level in the patient population. The research program we present aims at relieving the burden of these limitations using a genotype – endophenotype mapping strategy to shed light on disease mechanisms and identify - genetic variants to be used in a patient-stratification analysis. Using a large dataset of psychosis patients, unaffected relatives and unrelated controls with genotypic and endophenotypic data we will perform a comprehensive genotype – endophenotype - mapping through genome-wide linkage and association analyses. The results of the mapping will be fed into a patient stratification strategy coupling unsupervised clustering with a machine-learning construction of a classifier. The final objective is - to identify genetic subtypes of psychosis, provide a classifier for these subtypes and build subtype-specific genotype – endophenotype association maps. This potentially high-impact result-generating research program, along with a five-course - training program, Dr. Bramon’s supervision and the excellent research environment provided by UCL, will allow me to acquire the scientific and transferable skills and build the collaboration network necessary to launch my career as an independent - researcher. - - 2019-07-14, ongoing project - - - 2017-07-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - GENDOSIS - - - H2020-MSCA-IF-2016 - - - 747429 - - - - - RIJKSUNIVERSITEIT GRONINGEN - - - EUR 1 046 400 - - - Data Science and Systems Complexity Research Training Programme - - - EUR 2 092 800 - - - Netherlands - - - Higher or Secondary Education Establishments - - Today’s world is a highly complex system that is producing massive amounts of data daily. We can only progress towards urgent global priorities such as sustainable energy, personalized healthcare or the development of the - data-driven economy if we can predict the dynamic nature of such a system. This challenge calls for an integrated approach that uses data to understand the behaviour of complex systems, and for experts who can handle data and complexity problems for - society at large. - - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2016 - Co-funding of regional, national and international programmes - - - MSCA-COFUND-DP - Doctoral programmes - - - Netherlands - - - DSSC - - - H2020-MSCA-COFUND-2016 - - - 754315 - - - - - UNIVERSITY COLLEGE LONDON - - - EUR 195 454,80 - - - Enabling Visual IoT Applications with Advanced Network Coding Algorithms - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The latest advances and integration of several key technologies such as wireless communications, low-power sensing, embedded systems, Internet protocols and cloud computing, have enabled the emergence of the Internet of Things - (IoT) paradigm. However, the ever-growing deployment of the visual sensing applications within IoT deployments is expected to strain the network and cloud infrastructures used to deliver and store massive amounts of visual data. To partly address - these challenges, prototypes of neuromorphic visual sensors, a.k.a. dynamic vision sensors (DVS), have been produced in the last two years. Instead of the conventional raster scan of video cameras, DVS devices record pixel coordinates and timestamps - of reflectance events in an asynchronous manner, thereby offering substantial improvements in sampling speed and power consumption. ENVISION argues that, in order to fully exploit the advantages of neuromorphic sensing for IoT applications, such - devices should be coupled with appropriate transmission and storage mechanisms that would take advantage of the visual data properties to achieve even higher bandwidth, power and storage efficiency. The ENVISION project aims at developing such - data-driven delivery and storage algorithms based on advanced network coding techniques for data acquired by both conventional frame-based video cameras and DVS devices. Specifically, ENVISION is pursuing three interconnected research objectives: (i) - designing advanced content-driven network codes for efficient transmission of the visual content captured by neuromorphic and conventional visual sensors to the cloud service under bandwidth and power constraints, (ii) developing novel content-aware - network codes for storage of the visual content under the cost-performance optimisation framework, and (iii) investigating approximate decoding techniques including both the theoretical analysis of the performance and the implementation of practical - low-complexity decoders. - - 2020-01-14, ongoing project - - - 2018-01-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ENVISION - - - H2020-MSCA-IF-2016 - - - 750254 - - - - - UNIVERSITAT AUTONOMA DE BARCELONA - - - EUR 170 121,60 - - - Generalized geometry: 3-manifolds and applications - - - EUR 170 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - Generalized geometry is a revolutionary approach to geometric structures pioneered by Hitchin in 2003, soon becoming an active topic catching the interest and bringing together the expertise of geometers and theoretical - physicists. Generalized complex structures, defined for even-dimensional manifolds, are both a genuinely interesting mathematical structure, providing insight of complex and symplectic geometry, and the suitable notion for some physical theories like - mirror symmetry. Odd-dimensional manifolds within generalized geometry have not been satisfactorily studied until the recent introduction of generalized geometry of type Bn and its study in my PhD thesis. There, the case of 3-manifolds drew special - attention thanks to the recent Thurston's geometrization theorem and the fact that the type-change locus of a 3-manifold is a link, bringing in knot and link theory. This action combines the generalized geometry expertise of the experienced - researcher with the host’s expertise on 3-manifold and knot and link theory in order to set a novel geometrical framework for structures on odd-dimensional manifolds, understand the case of 3-manifolds in depth, and create a two-way bridge between - these previously unrelated areas, with innovative applications in both. - - 2020-04-30, Grant Agreement signed - - - 2018-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - GENERALIZED - - - H2020-MSCA-IF-2016 - - - 750885 - - - - - OSPEDALE SAN RAFFAELE SRL - - - EUR 168 277,20 - - - Epigenetic approach for the treatment of obesity - - - EUR 168 277,20 - - - Italy - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - It has been estimated a threefold increase in the number of obese people in Europe since the 1980’s. Currently, EU countries spend an average of 7% of their public health budgets on diseases linked to obesity. The - socio-economic impact of obesity epidemic cannot be overrated. European societal needs require desperately a shift forward in the field of obesity research to be able to build new therapeutics strategies. Recent scientific evidences point toward a - role of epigenetic changes as major contributor in the obesity etiology. In the last decades, a huge amount of data clearly link epigenetic dysregulation to obesity onset. Yet, it remains unclear whether epigenetic dysregulation contributes - meaningfully to obesity epidemic. Because weight gain only occurs when energy intake exceed energy expenditure, burning off excess fuel represent an attractive path to reduce obesity when diet and exercise are not enough. My preliminary data indicate - the histone methyltransferases Suv420h1 and Suv420h2 as pivotal players in metabolism regulation. By using knockout mice specifically in brown adipose tissue, this project aims at dissecting the role of Suv420h proteins in the etiology of obesity. I - will combine in vivo and in vitro analyses and genome wide studies to: 1) dissect the role of Suv420h proteins in the epigenetic regulation of the pathways controlling weight balance in response to nutritional or environmental stimuli; 2) identify - genes involved in the generation, maintenance or transmission of the epigenetic memory of exposure; 3) provide useful markers or therapeutic targets to treat obesity and metabolic diseases. My results have the potential to translate into - therapeutics. This research will contribute to provide new clinical targets against obesity. The Experienced Researcher will emerge from the project with new skills, and the capability to lead her own research group. - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-SE - Society and Enterprise panel - - - Italy - - - EASY - - - H2020-MSCA-IF-2016 - - - 746974 - - - - - FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA - - - EUR 168 277,20 - - - Electromyography-driven musculoskeletal modelling for biomimetic myoelectric control of prostheses with variable stiffness actuators - - - EUR 168 277,20 - - - Italy - - - Research Organisations - Chiara Andreoli - Tel.: +3901071781854 - Fax: +39 010 7170817 - - Upper limb loss affects 94.000 individuals in Europe. Advanced treatments rely on myoelectric prostheses controlled by amputees’ electromyograms or EMG. Despite expected benefits, today's schemes provide limited re-gain of - functionality and lack of bio-mimesis, i.e. they use: (1) direct mapping between EMG and prosthesis joint angle, disregarding underlying neuromusculoskeletal processes, and failing to generalize to unseen conditions (robustness lack), (2) stiff - actuators not mimicking biological compliant joints, preventing natural motion (functionality lack). MIMICS proposes a biomimetic paradigm: (1) a modelling formulation that simulates amputee’s phantom limb musculoskeletal dynamics as controlled by - EMGs, and (2) prostheses with variable stiffness “soft” actuators. This opens to next-generation “soft” prostheses that can mimic biological limb functionality and robustness; a priority of current European policies and technology roadmaps, with - estimated initial markets for functional myoelectric prostheses of €1 billion. MIMICS combines required interdisciplinary skills on soft actuation (host), neuromusculoskeletal modelling (fellow), and clinical bionic reconstruction (secondment). The - career development plan is tailored on fellow’s needs: new skills acquisition (soft actuation/clinical prosthetics), project/teamwork management, open science/gender aspects care, ERC grant writing support. The action transfers fellow’s pre-acquired - knowledge to the host and opens cooperation with secondment institute, thus increasing host’s visibility in myoelectric control and clinical prosthetics. The secondment expands MIMICS outcomes to boarder clinical perspectives and boosts knowledge - transfer among organizations. Outreach activities plan to improve public understanding of MIMICS achievements, socio-economical potentials and clinical benefits. This all is set to improve fellow’s career prospects and form a European network of - excellence in neurorehabilitation technologies - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - MIMICS - - - H2020-MSCA-IF-2016 - - - 747045 - - - - - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - - - EUR 3 767 040 - - - The launch of a new industrial PhD programme at EPFL - - - EUR 7 534 080 - - - Switzerland - - - Higher or Secondary Education Establishments - - The “École Polytechnique Fédérale de Lausanne” (EPFL) is one of the two Federal Institutes of Technology in Switzerland. EPFL has three missions: i) education, ii) research, and iii) technology transfer. The EPFL is - successful in fulfilling these missions, and is ranked as one of Europe’s top institutions with respect to education, research, training-through-research and innovation. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2016 - Co-funding of regional, national and international programmes - - - MSCA-COFUND-DP - Doctoral programmes - - - Switzerland - - - EPFLinnovators - - - H2020-MSCA-COFUND-2016 - - - 754354 - - - - - EIDGENOESSISCHE ANSTALT FUER WASSERVERSORGUNG ABWASSERREINIGUNG UND GEWAESSERSCHUTZ - - - EUR 175 419,60 - - - Exposure of aquatic ecosystems to antifungal azoles : assessment of occurence and fate in sediment, water and aquatic organisms - - - EUR 175 419,60 - - - Switzerland - - - Research Organisations - - This project aims to provide a comprehensive characterization of the exposure of aquatic organisms to antifungal azoles (AFAs), an emerging pollutant family of particular concern as regard to their endocrine disrupting - effects, in the frame of their environmental risk. To this end, this project will address different scientific and technical challenges as regards distribution, bioavailability, toxicokinetic, and (bio)transformation products ((bio)TPs) of AFAs. For - this purpose , a multi-disciplinary approach, based on bio-monitoring, passive sampling, effect-driven approach, cutting-edge high resolution mass spectrometry-analyses and laboratory experiments will be implemented. This comprehensive approach will - allow (1) to characterize the distribution of AFAs in aquatic systems between sediment, surface water and biota; (2) to identify bioTPs (and biotransformation pathways) of AFAs at different trophic levels but also TPs from other relevant processes - (e.g. hydrolysis). This project is original and innovative since it aims to gain knowledge on exposure and identity of (bio)TPs and thus addresses a crucial issue in the assessment of environmental contamination by emerging pollutants and their - associated risk. In addition, it proposes to better link exposure and hazard by studying the bioavailability of potentially hazardous chemicals directly in the organisms. It also compare passive sampling vs biomonitoring at different trophic level - for a more relevant exposure monitoring of emerging pollutants such as AFAs. This might also enhance human health risk assessment by providing tools for better evaluate exposure, and so risk, associated to consumption of contaminated food (i.e. - fish). Finally, if we focus in the present project on AFAs and their (bio)TPs, the approach proposed here could provide a conceptual framework for exposure assessment of other classes of emerging contaminants that would help to enhance actual - environmental risk assessment for aquatic organisms. - - 2019-09-14, ongoing project - - - 2017-09-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - EXPOZOL - - - H2020-MSCA-IF-2016 - - - 744052 - - - - - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - - - EUR 183 454,80 - - - Modulating and Profiling Receptor Tyrosine Kinase S-palmitoylation in Breast Cancer - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Breast cancer is one of the most diagnosed cancers and the leading cause of cancer death in women worldwide. Breast cancer cells need activated receptor tyrosine kinases (RTKs) to invade, proliferate, and metastasize. - Increased activity and overexpression of RTKs is associated with poor prognosis for breast cancer patients. Therefore, multiple RTKs have emerged as attractive therapeutic targets. However, resistance to therapies is a persistent problem for the - development of therapeutics targeting RTKs. New and innovative approaches to effectively target these receptors are required. Recently S-palmitoylation has been identified as an important post-translational modification that regulates signal - transduction, protein trafficking and degradation of specific RTKs in breast cancer. The substrate scope, role, extent of dysregulation and the enzymes responsible for the S-palmitoylation of specific substrates in breast cancer is largely unknown. - In this context, the aim of the proposed project is to implement novel chemical biological tools and methods, to gain insight in the extent, regulation and role of S-palmitoylation of RTKs in breast cancer. This insight will facilitate the - identification of new approaches to therapeutically target RTKs in breast cancer. - - 2019-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - RTKPalm - - - H2020-MSCA-IF-2016 - - - 750409 - - - - - VYSOKA SKOLA CHEMICKO-TECHNOLOGICKA V PRAZE - - - EUR 142 720,80 - - - Novel MAterial and Process Design for ReVerse Electrodialysis-Water ELectrolysisEnergy System - - - EUR 142 720,80 - - - Czech Republic - - - Higher or Secondary Education Establishments - - Development of renewable energy resources that can address energy and environmental issues is currently the top global challenge. Reverse Electrodialysis (RED) is a highly innovative technology for conversion of salinity - gradient energy into electricity. Water electrolysis is a promising option for hydrogen production from renewable energy resources. Recently, a novel approach combining RED and Alkaline Polymer Electrolyte Water Electrolysis (APEWE) was reported for - sustainable hydrogen production. However, this process achieved low efficiency: RED suffers from the negative impact of multivalent ions on power generation, whereas APEWE lacks highly conducive and stable membrane separators and polymer binders. The - MARVEL project aims to i) endow monovalent ion selectivity for RED membranes to reduce the influence of multivalent ions ii) develop novel, fully characterized membrane separators and polymer binders for APEWE iii) test RED-APEWE process with these - new materials iv) perform a techno-economic assessment for commercial feasibility. The ultimate goal of MARVEL is to broaden the knowledge and expertise of the researcher, Dr. Ramato Ashu Tufa, through high-quality research training in the emergig - area of renewable energy involving multidisciplinary investigation approaches and intersectoral secondments. This allows him to establish a long-standing relationship with his institute and increase his professional network across Europe. An - effective dissemination of project results and knowledge will be implemented through presentations of results in major conference, seminars, publications in high-impact peer reviewed journals, project web page, open days etc. Profound outputs from - MARVEL will significantly contrubte towards establishment of a strong scientific and technical base for European science and technology, foster the competitiveness and growth of EU economy with a positive impact on the major objectives of energy - policy for sustainability and security. - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Czech Republic - - - MARVEL - - - H2020-MSCA-IF-2016 - - - 748683 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 246 668,40 - - - Redox-responsive Magnetic Materials based on Polynuclear Organometallics - - - EUR 246 668,40 - - - France - - - Research Organisations - - This proposal describes the synthesis of novel functional materials by incorporating high spin octahedral metal clusters with fascinating electronic and magnetic properties into polymeric assemblies. The resulting highly - redox-responsive magnetic materials will be of great interest for a variety of applications including the storage and transfer of electrical charge, gas separation via magnetic selectivity, electrocatalysis, and long range cooperative magnetic - properties will also be investigated. The experienced researcher (Dr. Musgrave) wishes to spend 24 months at Harvard University to focus on synthesis and redox activity under the supervision of Prof. Theodore Betley, and 12 months at the Centre de - Recherche Paul Pascal (CRPP) to carry out magnetic measurements and data modelling under the supervision of Dr. Rodolphe Clérac. The complementary expertise of Prof. Betley (cooperative redox chemistry and catalysis) and Dr. Clérac at the CRPP - (electronically active and magnetic materials) are ideally suited for the completion of research objectives. Dr. Musgrave trained in the Manners group at the University of Bristol, and has extensive experience in metallopolymer synthesis and - characterisation, which is of great relevance to the project. With an MSCA fellowship, Dr. Musgrave hopes to gain valuable experience in the fields of redox catalysis and magnetic materials, build a network of long-lasting collaborations with - international scientists, and improve her leadership and management skills. The fellowship will have an extremely positive impact on her chances of obtaining an independent research position in the EU, and on the success of her career. - - 2020-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - France - - - RMTBRC - - - H2020-MSCA-IF-2016 - - - 752684 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 183 454,80 - - - Land Use and Resource Management at the Agricultural - Forest Frontier - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - In this fellowship, I aim to explore the trade-off and synergies between conservation and commodity production through an Ecosystem Services (ES) lens in order to determine how sustainable land use practices can be created and - strengthened over time, and to extend knowledge on ES within broader land use, and natural capital research. I will carry out targeted fieldwork to investigate the following research lines: 1) how ES are defined and conceptualised as commodities and - how these relate to more established ‘land’ commodities. This research line will include ES to humans, but also factors causing ecosystem change that can affect the long-term resilience of such ecosystems, by examining selected drivers of land use - change. Research line 2) relates to the impact of appropriation of land for commodities (e.g., the demand for cash crops such as soy, biofuels and land used for livestock production or conservation) on local communities, and the global economy and - policies that may drive (the current or any) 'land grabs'. I will take into account the discourse, practices and social relationships around land use that are currently unfolding within the 'realpolitik' of a studied region. These phenomena are - highly debated yet remain poorly understood and should become key analytical domains for academics insofar that they are related to broader processes of economic globalization, biodiversity loss and climate change. The findings will be complementary - to climate change mitigation efforts and feed into policy processes around securing food security, with an objective to not only contribute to sustainable land use practices but to promote the livelihood opportunities and environmental quality of - (often) marginalized communities living in and around contested land. - - 2019-05-01, ongoing project - - - 2017-05-02 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - LARMAR - - - H2020-MSCA-IF-2016 - - - 745744 - - - - - RUHR-UNIVERSITAET BOCHUM - - - EUR 119 595,60 - - - The Continuation of Politics with Other Means: War and Protest, 1914-2011 - - - EUR 119 595,60 - - - Germany - - - Higher or Secondary Education Establishments - - "This project looks at the political means employed by those who, for various reasons, resorted to protest during times of war in the period from the First World War to the Iraq War. In most cases, the challengers embraced - alternative means of political articulation due to the established channels of political decision making being controlled by the supporters of the war in question. Case studies illuminate the manifestations of war-time protest in different wars - including both the well-known and some of the "forgotten wars": First World War, Spanish Civil War, Second World War, Korean War, Vietnam War, Soviet War in Afghanistan, Falklands War, Kosovo War and Iraq War. The project pursues the objective to - articulate the relationship between war and protest and to develop further the debate surrounding war as a channel of cultural, social and political change. It will advance research into the comparative dimension of war-time protest by embedding this - investigation in an analytical framework focused on the methods and questions of historical enquiry into social movements, and to give further specificity to the debate on processes of politicisation and depoliticisation with particular focus on the - variety of motivations that drove war-time protest beyond just pacifism. This analysis combines methods from the history of protest and social movements, the history of war, the history of political thought as well as film and visual studies. The - project provides conceptual tools and evidence on the pre-history of present-day protests, e.g. against U.S. unilateralism in Iraq. Via a number of publications and engagement events, especially in conjunction with public film screenings, it will - create impact by intervening in current debates about the repercussions of global warfare and by furthering public awareness of the crucial historical role of war-time protest in the European political heritage." - - 2019-03-31, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - COPWOM - - - H2020-MSCA-IF-2016 - - - 748012 - - - - - UNIVERSITEIT MAASTRICHT - - - EUR 177 598,80 - - - Behavioural Economics in Network Games - - - EUR 177 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Three aspects of social interaction shall be combined, namely the diffusion of information in a social network, the formation of social networks, and behavioural (i.e. irrational) aspects in decision making. These three areas - are crucially interdependent: - - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - BEING - - - H2020-MSCA-IF-2016 - - - 747614 - - - - - AARHUS UNIVERSITET - - - EUR 200 194,80 - - - Quantification of oxidative sulphur cycling in marine sediments - - - EUR 200 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - The goal of this proposal is to quantify the rates and processes of sulphide oxidation in coastal sediments. The marine sulphur cycle is driven by the reduction of sulphate to sulphide coupled to microbial decomposition of - organic matter, a process which is responsible for up to 50 % of carbon mineralisation in coastal sediment and is intimately connected to earth’s biogeochemical evolution. The sulphide produced by sulphate reduction may either react with Fe to be - buried as pyrite or may be oxidised through different pathways and intermediates. The amount of sulphide that is oxidised in marine sediments is not known, yet oxidative sulphur cycling has critical implications for estimates of sulphate reduction, - sub-seafloor carbon mineralisation, methane oxidation, microbial metabolism and the interpretation of ancient and modern stable isotope signatures. Quantification of oxidative sulphur cycling, including sulphide oxidation rates, the formation of key - intermediate species and associated stable isotope effects is therefore fundamental to our understanding of sub-seafloor biogeochemistry. - - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - SedSulphOx - - - H2020-MSCA-IF-2016 - - - 746872 - - - - - UNIVERSITEIT MAASTRICHT - - - EUR 177 598,80 - - - Learning to bracket broadly - - - EUR 177 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - As a consequence of reforms of the social security systems in the EU, consumers increasingly face numerous investment decisions that involve risk, such as how to allocate their retirement savings between risky and safe assets. - However, consumers often fail to make optimal choices. A key aspect in this context is whether and how people integrate (or “bracket”) the many different choices under risk they face. Evidence suggests that people often bracket narrowly, i.e., they - view each choice in isolation and not in the context of the other choices they face, thereby often making choices that are not in their best interest. - - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - BROAD - - - H2020-MSCA-IF-2016 - - - 749741 - - - - - UNIVERSITEIT UTRECHT - - - EUR 177 598,80 - - - New non perturbative methods for out-of-equilibrium quantum field theory - - - EUR 177 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - A full understanding of the out-of-equilibrium dynamics of many-body quantum systems is one of the ultimate goals of statistical physics. It is often extremely difficult to compute how physical quantities evolve with time in - these settings, and to know when and how these systems eventually can reach some form of equilibrium. This difficulty is specially marked in systems described by quantum field theory, where non equilibrium dynamics are still less well understood than - in discrete lattice models and quantum spin chains. - - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - NpQFT-NEq - - - H2020-MSCA-IF-2016 - - - 750092 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 158 121,60 - - - The influence of Environmental Variability On Mussel Aquaculture and adaptation in the context of global ocean change - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - Global ocean change (GOC, including warming and acidification) poses one of the largest threats to marine fisheries and aquaculture. Yet, there are still few predictive consequences, due to the limited understanding of - species’ in situ responses. Recent studies suggest that spatial differences in environmental conditions influence physiological tolerances of marine populations. This project tests the hypothesis that environmental variability of multiple stressors - (temperature, pH, salinity) enhances physiological hardiness of sensitive early life-stages of an economically valuable mollusk, the mussel Mytilus galloprovincialis. The project implements a novel, three-pronged, multidisciplinary approach using (1) - population comparisons to assess performance of mussels from sites of low and high environmental variability, (2) mild stress exposures to test for enhanced physiological performance in the field, and (3) larval cultures to assess proteomic responses - to temporal variability of multiple stressors and carryover effects to juveniles. This project includes collection of oceanographic time-series data at field sites (including at an aquaculture farm), with state-of-the-art pH sensors, to identify - frequency of stress events and inform experimental design. This still rare approach, using in situ data with laboratory studies, improves environmental realism in GOC studies. The project addresses a crucial gap in the current understanding of - coastal environmental variability and multiple stressors and has direct application to aquaculture practices. By combining the researcher’s and host’s expertise on marine physiology related to GOC pressures, this project will advance innovations in - the field of GOC biology, state-of-the-art pH sensor technology transfer, and applied proteomics, and will thus become an important step forward in the career of a Researcher dedicated to GOC biology, and strengthen European expertise in these - fields. - - 2019-11-15, ongoing project - - - 2017-11-16 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - EVOMA - - - H2020-MSCA-IF-2016 - - - 747637 - - - - - UNIVERSITEIT MAASTRICHT - - - EUR 177 598,80 - - - Wage transparency in companies - - - EUR 177 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - How much information about the wage structure should a company provide to its employees? Existing research in economics does not provide clear recommendations in this respect. Transparent information about the wages within a - company may have a positive impact on employee satisfaction and motivation, because wage secrecy creates distrust and favours discriminatory practices. Yet, it is unclear whether the benefits of wage transparency are larger than the potential harm: - Unequal wage profiles, if made transparent, trigger social comparisons among employees that may destroy work motivation and increase the likelihood of leaving the firm. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - WAGETRANS - - - H2020-MSCA-IF-2016 - - - 745894 - - - - - UNIVERSITA DEGLI STUDI DI PARMA - - - EUR 244 269 - - - Using consumer science to improve healthy eating habits - - - EUR 244 269 - - - Italy - - - Higher or Secondary Education Establishments - - Although modern consumer can make informed decisions about the types and quantity of food which are best for a healthy lifestyle, an increase in diet-related health problems -caused by unhealthy and over-eating– has been - recorded in the European Union in recent years. - - 2020-06-27, ongoing project - - - 2017-06-28 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Italy - - - CONSUMEHealth - - - H2020-MSCA-IF-2016 - - - 749514 - - - - - POLITECHNIKA LUBELSKA - TECHNICKA UNIVERZITA V KOSICIACH - UNIVERSIDADE DO MINHO - ZAMAK MERCATOR SPOLKA Z OGRANICZONAODPOWIEDZIALNOSCIA - BORRA SRO - SEZ KROMPACHY AS - - - EUR 1 305 000 - - - Investigation and development of a new generation of machines for the processing of composite and nanocomposites materials - - - EUR 1 305 000 - - - Poland - Slovakia - Portugal - Poland - Czech Republic - Slovakia - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The main research goal of the NEWEX Project is the construction and testing of the new innovative extruder. By the application of a new, patented concept of vital parts: innovative active grooved feed section (IAGFS), original - rotational barrel segment (ORBS) and special screw (SS) a completely new breakthrough technology of extrusion and plasticizing systems will be achieved. It will ensure manufacturing the products of improved properties and will enable processing - materials that couldn’t be processed so far, as well as food materials, cosmetic and pharmaceutical. In parallel to the main RTD activities the NEWEX project is aiming at industry-academia cooperation and transfer of knowledge between organizations - from central-eastern and Western Europe. All the project’s activities will be performed by thoroughly planned secondments and appropriate hosting institutions between industrial and academic partners. The workplan consists of 7 Workpackages, out of - which: WP1-4 focus on the investigation of extruder, extrusion process and extrudate properties and tasks aiming at the selection of the best solution of new extruder vital parts, than construction and testing of new generation extruder. WP5 - concentrates on networking activities (workshops, training, knowledge exchange, etc.). WP6 aims at knowledge dissemination (participation in conferences, fairs, publications, etc.), WP7 is dedicated to management and administration of the whole - project. The consortium consists of 6 organizations: 3 representing academic partners and 3 representing industry partners. Project is coordinated by Lublin University of Technology (Poland). Partners are: Technical University of Kosice (Slovakia), - University of Minho (Portugal), Zamak-Mercator LLC (Poland), SEZ-Krompachy a.s. (Slovakia) and Borra s.r.o. (Czech Republic). Realization of NEWEX project will foster the real industry-academia cooperation which is of the key importance in terms of - European Research Area development strategy. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Poland - - - NEWEX - - - H2020-MSCA-RISE-2016 - - - 734205 - - - - - OSPEDALE SAN RAFFAELE SRL - - - EUR 168 277,20 - - - Spatiotemporal dynamics of CD8+ T cell responses to hepatocellular carcinoma - - - EUR 168 277,20 - - - Italy - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - CD8+ T cells have a key role in eliminating tumors that affect the liver. The protective capacity of these cells relies on their ability to migrate to the liver, recognize antigens and deploy effector functions. While some of - the rules that characterize CD8+ T cell behavior in the cancerous liver have been characterized at the population level, we have only limited knowledge of the precise dynamics of intrahepatic CD8+ T cell conduct at the single-cell level. In - preliminary data for this project we have developed advanced imaging techniques that allow us to dissect the interactive behavior of CD8+ T cells within the mouse liver at an unprecedented level of spatial and temporal resolution. We predict that - this approach, combined with a new model of hepatocellular carcinoma created ad hoc, will generate novel mechanistic insights into the spatiotemporal determinants that govern the capacity of CD8+ T cells to home and function in the tumor-bearing - liver. - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-SE - Society and Enterprise panel - - - Italy - - - Hepatocarcinoma IVM - - - H2020-MSCA-IF-2016 - - - 753534 - - - - - NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU - - - EUR 208 400,40 - - - High-Performance Indexing for Emerging GPU-Coupled Databases - - - EUR 208 400,40 - - - Norway - - - Higher or Secondary Education Establishments - - "Index structures are foundational to the performance of database systems and large-scale simulations. Even small advances in indexing can therefore have widespread, sweeping impact on both industry competitiveness and - scientific productivity. The confluence of several hardware trends is setting the stage for disruptive innovation in database indexing: deescalating costs of memory make it feasible to organise most of the "hot", frequently accessed data in memory - rather than on disk; and increasingly commonplace accelerators such as graphics processing units (GPUs) offer large-scale parallelism with a lower energy footprint. Thus, in-memory indexing that exploits GPUs could be much cheaper, faster, and - greener. - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Norway - - - CoupledDB - - - H2020-MSCA-IF-2016 - - - 753810 - - - - - UNIVERSITEIT MAASTRICHT - UNIVERSITE DE STRASBOURG - UNIVERSIDAD DE ALICANTE - UNIVERSITAET AUGSBURG - QUEEN MARY UNIVERSITY OF LONDON - - - EUR 3 865 881,60 - - - European Intellectual Property Institutes Network - Innovation Society - - - EUR 3 865 881,60 - - - Netherlands - France - Spain - Germany - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - EIPIN IS is a comprehensive project at the forefront of multidisciplinary research, examining the role of intellectual property (IP) as a complex adaptive system in innovation. The focus will be on the European regulatory - framework for fostering innovation with the aim of enhancing Europe’s capacity for innovation-based sustainable economic growth. - - - 2021-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-EJD - European Joint Doctorates - - - Netherlands - - - EIPIN IS - - - H2020-MSCA-ITN-2016 - - - 721733 - - - - - UNIVERSITEIT UTRECHT - - - EUR 177 598,80 - - - Linking Zeolite Porosity to Molecular Diffusion at the Single Crystal Level - - - EUR 177 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Zeolites are the key enablers of diverse chemical reactions, fulfilling a role of utmost importance in (petro-) chemical industry. They contain a precisely defined micropore network, which exposes a 3-D distribution of - Brønsted acid sites. The performance of zeolites relies to a great extent on the accessibility of these acid sites, making the facile molecular diffusion through the zeolite pore network essential. For this reason, methods for hierarchical porosity - development – such as steaming – are used to increase the molecular uptake of zeolites. These methods introduce auxiliary meso- and macroporosity, which maximize the utilization of the catalyst volume, and thereby improve the catalyst performance and - lifetime. - - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - ZeoPoreDiff - - - H2020-MSCA-IF-2016 - - - 748563 - - - - - UNIVERSITEIT MAASTRICHT - UNIVERSITAETSKLINIKUM AACHEN - KAROLINSKA INSTITUTET - - - EUR 3 832 965,36 - - - International Network for Training on Risks of vascular Intimal Calcification And roads to Regression of cardiovascular diseasE - - - EUR 3 832 965,36 - - - Netherlands - Germany - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Cardiovascular disease remains one of the major challenges of contemporary society, being responsible for a staggering 47% of deaths in Europe. Vascular calcification in particular requires immediate attention as it is - strongly associated with increased cardiovascular mortality and morbidity, and is recognised as an important independent risk factor for cardiovascular death. Recent reports demonstrate that especially punctuated and spotty calcifications - (microcalcifications) in the plaque are life-threatening. Microcalcifications are particularly prominent in the vulnerable atherosclerotic plaque that is at high risk of rupture, a cardinal event that can cause thrombosis, infarct, cardiac arrest, - stroke and death. In fact, 20% of European deaths are directly attributable to thrombotic rupture of a vulnerable plaque; a clear indication that current treatments and preventive measures are insufficient. Recent findings suggest a link between - vascular smooth muscle cell phenotype mediated calcification and inflammation, which could underlie the plaque destabilising effects of microcalcification. However, a comprehensive view on what causes microcalcification and its impact on plaque - stability remains elusive and there is an urgent need to translate experimental findings into adequate diagnostic, preventive and therapeutic solutions. INTRICARE is shaped to address the urgent unmet medical needs concerning calcification-induced - vulnerable plaques and is guided by the academic and industrial demand for a new generation of entrepreneurial scientists that have the skills, expertise and knowhow to expedite our understanding of vascular calcification and translation thereof into - concrete, effective clinical solutions. The INTRICARE ESRs harbour ongoing vitamin K-supplementation trials that will be pivotal in the identification of selective biomarkers for microcalcification and subsequent development of strategies for - prevention or amelioration of vulnerable plaque formation. - - 2021-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-EJD - European Joint Doctorates - - - Netherlands - - - INTRICARE - - - H2020-MSCA-ITN-2016 - - - 722609 - - - - - Eidgenössische Technische Hochschule Zürich - Eidgenössische Technische Hochschule Zürich - - - EUR 150 000 - - - Multi-well High-resolution Electrophysiology Platform - - - EUR 150 000 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - MwHresEP: Multi-well High-resolution Electrophysiology Platform - - 2018-11-30, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Switzerland - - - MwHresEP - - - ERC-2016-PoC - - - 755383 - - - - - UNIVERSITEIT MAASTRICHT - - - EUR 165 598,80 - - - Liver steatosis drives muscle atrophy in type 2 diabetes patients. - - - EUR 165 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Problem: Muscle atrophy is defined as a decrease in muscle mass, and is a major problem in many patients with type 2 diabetes (T2D). Previous studies have linked a fatty liver to the development of muscle atrophy in T2D - patients, but the exact mechanisms are unknown. Background: Many T2D patients are characterised by hepatic steatosis. We have preliminary data to suggest that secretion products from the steatotic liver play an important role in the development of - muscle atrophy. Aim: we will identify how hepatic steatosis affects the liver secretory profile, and we will determine the impact of these secretion products on muscle protein metabolism. We will also identify novel liver-secreted proteins that are - causally related to muscle atrophy, and validate these proteins in patients with hepatic steatosis and T2D. Hypothesis: We hypothesize that hepatic steatosis changes the liver protein secretion profile which negatively impacts muscle mass. We also - expect to identify proteins that are causally related to muscle atrophy, and to validate these proteins in patients with liver steatosis and T2D. Methods: We will use a translational approach in which leads from human studies will be investigated in - cell- and animal experiments and subsequently tested again in human subjects. We will combine functional metabolic assays, high-throughput molecular biology approaches, cell biology and in vivo studies to investigate whether secretion products from - the liver play a role in the development of muscle atrophy. Outcome: This project is the first to investigate whether secretion products from the liver directly contribute to the loss of muscle mass in T2D patients. Our research is innovative and - will provide crucial proof-of-concept information to further develop therapeutic approaches to treat or prevent muscle atrophy in T2D patients. - - 2020-02-20, Grant Agreement signed - - - 2018-02-21 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Netherlands - - - LiSDMA - - - H2020-MSCA-IF-2016 - - - 748944 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 150 000 - - - Innovative fungal strains for producing blue cheeses - - - EUR 150 000 - - - France - France - - - Research Organisations - Research Organisations - - The ERC project GenomeFun has revealed a substantial genetic and phenotypic variability within Penicillium roqueforti, which is the fungus used for the maturation of blue cheeses. The ERC project GenomeFun has also shown the - existence of different genetic clusters harboring specific traits and has allowed the development of a protocol for inducing in the laboratory the natural process of sexual reproduction in this fungus. The present PoC BLUE project aims at proving the - possibility to obtain and identify, in sexual progeny, strains of P. roqueforti with novel combinations of traits of industrial interest. This would enable strain improvement, and would allow the production of blue cheeses with innovative - characteristics, as desired by producers and consumers. Thus the objective of the present PoC project is to identify progeny with interesting combinations of traits. These strains will then be protected and commercialized. The project therefore also - aims at identifying the market and the best strategy for exploitation, firstly by defining the most suited approach for the protection and exploitation of intellectual property, taking into account the market practices and conditions, and secondly, - by verifying the legal dispositions applicable to sexual progeny of micro-organisms in the field of “novel food”, biodiversity and genetic resources protection. The legislative framework raises interesting questions in the context of recent treaties - on biodiversity. The consequences of the recent laws on biodiversity on the use and protection of micro-organisms as intellectual property in the fields of food are still unclear. The results of these investigations could thus serve as a model case. - - 2019-02-28, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - France - - - BLUE - - - ERC-2016-PoC - - - 754761 - - - - - KING'S COLLEGE LONDON - - - EUR 183 454,80 - - - Differentiated health impacts of primary and secondary ultrafine particles - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Exposure to particulate matter (PM) has been linked to negative health effects. Traditionally attributed to PM<10µm and<2.5µm, negative health effects may be enhanced with decreasing particle size, suggesting that - ultrafine particles (UFP, PM<0.1µm) might be responsible for what has previously been attributed to larger size fractions of PM. - - 2019-09-06, ongoing project - - - 2017-09-07 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - Health1UP2 - - - H2020-MSCA-IF-2016 - - - 747882 - - - - - TECHNISCHE UNIVERSITEIT DELFT - TECHNISCHE UNIVERSITEIT DELFT - - - EUR 2 499 474 - - - Virtual Seismology: monitoring the Earth's subsurface with underground virtual earthquakes and virtual seismometers - - - EUR 2 499 474 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - If it were possible to place seismometers and seismic vibrators anywhere below the ground in, for example, an induced-earthquake-sensitive area, we could measure the source mechanism of actual earthquakes, monitor the - geomechanical state of the area over time, and quantify the ground motion caused by possible future earthquakes. Moreover, we could monitor fluid flow in aquifers, geothermal reservoirs or CO2 storage reservoirs, with unprecedented resolution. - Unfortunately, placing seismic instruments anywhere below the ground is not practically feasible. - - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Netherlands - - - VirtualSeis - - - ERC-2016-ADG - - - 742703 - - - - - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - - - EUR 149 959 - - - Novel water splitting catalysts for efficient alkaline electrolyzers - - - EUR 149 959 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Renewable energies such as solar and wind are intermittent and require efficient storage methods. One of the most promising methods for renewable energy storage is water splitting, which converts these energies into hydrogen - fuel. Solar or wind-driven water splitting can be done using electrolyzers, and alkaline electrolyzers are potentially scalable because they do not use precious metal catalysts. However, current alkaline electrolyzers employ catalysts that have low - efficiencies and are prone to corrosion. This project aims to apply several novel classes of water splitting catalysts developed in our ERC Starting Grant project in alkaline electrolyzers. The catalysts are inexpensive and have higher energy - efficiencies than those employed in commercial alkaline electrolyzers. They are potentially more stable as well. The goal of the project is to provide technology demonstrators for the use of these catalysts in alkaline electrolyzers, which is - expected to result in higher efficiencies and stability at a similar cost. - - 2018-10-31, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Switzerland - - - ELECTROCAT - - - ERC-2016-PoC - - - 754760 - - - - - THE UNIVERSITY OF SHEFFIELD - THE UNIVERSITY OF SHEFFIELD - - - EUR 149 995 - - - Gene Editing as Therapeutic Strategy for C9ORF72 Linked ALS/FTD - - - EUR 149 995 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Expansion of a hexanucleotide repeat G4C2 in the non-coding region of chromosome 9 open reading frame 72 (C9orf72) is the most common genetic cause for amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). ALS - is a fatal condition characterized by progressive motor deficits, degeneration of upper and lower motor neurons (MNs) and death from neuromuscular respiratory failure in the majority of afflicted individuals within 3-5 years. Currently, the economic - burden of care and treatment for patients with ALS/FTD is expensive and continues to significantly rise in Europe and worldwide. While significant genetic discoveries have been made in the field, they have not yet translated to treatment options for - patients with ALS and FTD. Thus, research efforts aimed at identifying therapeutic targets are of the utmost importance to enable therapeutic development for these devastating disorders. In this ERC Proof of Concept project, we will design, optimise - and test gene therapy vectors containing CRISPR/Cas9 system to selectively remove the pathogenic ALS/FTD-related C9orf72 hexanucleotide repeat expansion in mouse models of C9orf72-related ALS, with the ultimate aim of designing a therapy for patients - with C9orf72-related ALS/FTD. The ultimate benefit of this approach goes far beyond just ALS/FTD however. A successful CNS gene therapy for C9orf72 related disease potentiates the prospect of developing similar approaches to treat multiple disease - scenarios amenable to gene modification. Indeed, growing evidence suggests that C9orf72 repeat expansions also contribute to a wide spectrum of neurodegenerative diseases such as Alzheimer’s, Huntington’s, multiple sclerosis, Parkinson’s disease and - cerebellar ataxias. We therefore anticipate that our strategy could be beneficial for other neurological conditions. - - 2018-11-30, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - CORFEDITING - - - ERC-2016-PoC - - - 754994 - - - - - Eidgenössische Technische Hochschule Zürich - Eidgenössische Technische Hochschule Zürich - - - EUR 2 130 088 - - - Cold Ion Chemistry - Experiments within a Rydberg Orbit - - - EUR 2 130 088 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - "To date no experiment has investigated ion-molecule reactions at temperatures significantly below about 20 K, for two reasons: (i) Cooling the translational and internal degrees of freedom of ions and molecules is extremely - challenging. (ii) Even very weak stray electric fields accelerate the ions. A potential difference of only 1 mV across the reaction volume imparts a kinetic energy of 1 meV to ions, which corresponds to a temperature of about 12 K. Quantum mechanical - effects arising from the translational and the frozen or hindered rotational motion of the reactants in the intermolecular potential are only expected to be significant below 20 K and have therefore not been observed yet in ion-molecule reactions, - even for reactions involving the lightest ions and molecules. This proposal aims at developing a new experimental method to study ion-molecule reactions at temperatures down to 100 mK and to study ion-molecule reactions involving light species, with - particular emphasis placed on the observation and quantification of quantum effects in low-temperature ion-molecule chemistry. To reach this goal, we will study the ion-molecule reactions within the orbit of a highly excited Rydberg electron, which - will shield the reaction from stray fields without affecting its outcome. To reach very low collision energies, we will use a merged-beam approach relying on a surface-electrode Rydberg-Stark deflector. In the preparatory phase of this proposal, we - have carried out a proof-of-principle measurement of the H2+ + H2 -> H3+ + H reaction below 1 K using a simplified version of the "ideal" instrument and demonstrated the feasibility of our method. We now plan to exploit the full potential of our - new approach and study important ion-molecule reactions in a temperature range thought until now to be experimentally inaccessible." - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Switzerland - - - CICERO - - - ERC-2016-ADG - - - 743121 - - - - - UNIVERSITY OF DUNDEE - UNIVERSITY OF DUNDEE - - - EUR 2 128 602 - - - Evolution of multicellularity and somatic cell specialization - - - EUR 2 128 602 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The evolution of multicellularity allowed specialization of cells into functions that support rather than cause propagation. While yielding immense gain of function, the organisation of these somatic cells into tissues and - organs required novel cell-cell signalling systems. We seek to identify the genetic changes that caused transitions to multicellularity and enabled cell specialization. We use genetically tractable Dictyostelia with multicellular structures that - contain from 1 to 5 cell-types to address these fundamental questions. Dictyostelia evolved from unicellular Amoebozoa and are subdivided into 4 major groups, with most novel cell-types appearing in group 4. We found that gene expression patterns - changed most frequently at the transition between groups 3 and 4, and that across groups ~10% of genes were alternatively spliced in the 5’UTR, indicative of promoter elaboration. Among known genes essential for multicellular development, those - involved in intracellular signal processing were mostly conserved between Dictyostelia and unicellular Amoebozoa, while those encoding exposed and secreted proteins (ESPs) were unique to Dictyostelia or groups within Dictyostelia. Starting from a - hypothesis that diversification of ESPs and gene regulatory mechanisms are major drivers of multicellular evolution, we will place unicellular relatives of Dictyostelia under selection to induce multicellularity, establish which genes are most - changed in evolved populations and whether this involves ESP families that are also most changed in Dictyostelia. We will overexpress altered genes in unicellular forms to assess whether this induces multicellularity. We will retrace evolution of - cell specialization by lineage analysis and phenotyping and seek correlations between cell-type innovation and alternative splice events and with emergence of novel signalling genes. Causality will be assessed by replacement of genes or promoters - with ancestral forms in evolved species and vice versa. - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - EVOSOM - - - ERC-2016-ADG - - - 742288 - - - - - HELSINGIN YLIOPISTO - HELSINGIN YLIOPISTO - - - EUR 2 500 000 - - - Atmospheric Gas-to-Particle conversion - - - EUR 2 500 000 - - - Finland - Finland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Atmospheric Gas-to-Particle conversion (ATM-GTP) is a 5-year project focusing on one of the most critical atmospheric processes relevant to global climate and air quality: the first steps of atmospheric aerosol particle - formation and growth. The project will concentrate on the currently lacking environmentally-specific knowledge about the interacting, non-linear, physical and chemical atmospheric processes associated with nano-scale gas-to-particle conversion (GTP). - The main scientific objective of ATM-GTP is to create a deep understanding on atmospheric GTP taking place at the sub-5 nm size range, particularly in heavily-polluted Chinese mega cities like Beijing and in pristine environments like Siberia and - Nordic high-latitude regions. We also aim to find out how nano-GTM is associated with air quality-climate interactions and feedbacks. We are interested in quantifying the effect of nano-GTP on the COBACC (Continental Biosphere-Aerosol-Cloud-Climate) - feedback loop that is important in Arctic and boreal regions. Our approach enables to point out the effective reduction mechanisms of the secondary air pollution by a factor of 5-10 and to make reliable estimates of the global and regional aerosol - loads, including anthropogenic and biogenic contributions to these loads. We can estimate the future role of Northern Hemispheric biosphere in reducing the global radiative forcing via the quantified feedbacks. The project is carried out by the - world-leading scientist in atmospheric aerosol science, being also one of the founders of terrestrial ecosystem meteorology, together with his research team. The project uses novel infrastructures including SMEAR (Stations Measuring Ecosystem - Atmospheric Relations) stations, related modelling platforms and regional data from Russia and China. The work will be carried out in synergy with several national, Nordic and EU research-innovation projects: Finnish Center of Excellence-ATM, Nordic - CoE-CRAICC and EU-FP7-BACCHUS. - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Finland - - - ATM-GTP - - - ERC-2016-ADG - - - 742206 - - - - - INSTITUTO DE ASTROFISICA DE CANARIAS - INSTITUTO DE ASTROFISICA DE CANARIAS - - - EUR 2 478 750 - - - Polarized Radiation Diagnostics for Exploring the Magnetism of the Outer Solar Atmosphere - - - EUR 2 478 750 - - - Spain - Spain - - - Research Organisations - Research Organisations - - POLMAG aims at a true breakthrough in the development and application of polarized radiation diagnostic methods for exploring the magnetic fields of the chromosphere, transition region and corona of the Sun via the - interpretation of the Stokes profiles produced by optically polarized atoms and the Hanle and Zeeman effects in ultraviolet (UV), visible and near-infrared spectral lines. To this end, POLMAG will combine and expand expertise on atomic physics, on - the quantum theory of radiation, on high-precision spectropolarimetry, on advanced methods in numerical radiative transfer, and on the confrontation of spectropolarimetric observations with spectral synthesis in increasingly realistic - three-dimensional (3D) numerical models of the solar atmosphere. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Spain - - - POLMAG - - - ERC-2016-ADG - - - 742265 - - - - - Eidgenössische Technische Hochschule Zürich - Eidgenössische Technische Hochschule Zürich - - - EUR 2 173 375 - - - Faster magic-angle spinning leads to a resolution revolution in biological solid-state NMR - - - EUR 2 173 375 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Solid-state NMR has recently made a significant impact on structural biology by providing atomic-resolution structures of several, previously uncharacterized proteins. A particularly relevant example is the Amyloid-beta (Aβ) - peptide linked to Alzheimer’s disease where we determined the atomic-resolution structure of Aβ(1-42) and of the Osaka mutant of Aβ(1-40). - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Switzerland - - - FASTER - - - ERC-2016-ADG - - - 741863 - - - - - UNIVERSITAET REGENSBURG - UNIVERSITAET REGENSBURG - - - EUR 2 458 200 - - - Photocatalytic Generation of CarbAnions for Organic Synthesis - - - EUR 2 458 200 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Light is a fascinating reagent for chemistry as it provides energy to drive reactions, but leaves no trace. In visible light photoredox catalysis the initial electron transfer from the excited dye to a substrate yields radical - anion or radical intermediates, which dominate the subsequent chemistry. Carbanions, which are the most important nucleophiles in organic chemistry, are typically not available from photocatalysis. The project PHAROS aims to overcome the current - limitation of visible light photocatalysis to radical chemistry and extend its use to carbon nucleophiles. To obtain carbanions for organic synthesis using visible light, we propose three specific project tasks: - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - PHAROS - - - ERC-2016-ADG - - - 741623 - - - - - INSTITUT POLYTECHNIQUE DE BORDEAUX - INSTITUT POLYTECHNIQUE DE BORDEAUX - - - EUR 2 415 848,75 - - - Electrochemically induced Asymmetry: from materials to molecules and back - - - EUR 2 415 848,75 - - - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Asymmetry is a very common feature of many systems, objects and molecules, that we use in our daily life. Actually, it is in a majority of cases the absolutely crucial ingredient for conferring a useful property to a system, a - prominent example being the chiral nature of pharmaceutically active compounds. Chemists have developed various approaches to generate asymmetry, from the molecular to the macroscopic scale, but are still facing major challenges when exploring - efficient alternative physico-chemical concepts for symmetry breaking. The global aim of ELECTRA is to propose so far unexplored and versatile strategies, based on the unconventional use of electrochemical phenomena, to generate asymmetry in chemical - systems at different length scales. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - France - - - ELECTRA - - - ERC-2016-ADG - - - 741251 - - - - - TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY - TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY - - - EUR 150 000 - - - Programming with Big Code - - - EUR 150 000 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Software synthesis aims to automate the creation of software by generating parts of software from a higher-level description. Until recently it was believed to be impossible to practically synthesize software beyond very small - fragments. However, synthesis based on learning from existing large code-bases (“Big Code”) is making synthesis into a practical reality . The purpose of this PoC is to develop a platform that would lead to commercialization of our technology to - improve programming productivity and code quality. We target two closely related applications: (1) Providing automatic assistance in programming tasks by learning from existing code, and (2) Providing on-line assessment of code quality as it is being - developed using learned models. These applications have the potential to dramatically reduce time-to-market of new software, and improve its quality and security. - - 2018-10-31, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Israel - - - AutoCode - - - ERC-2016-PoC - - - 727579 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 2 494 117 - - - An Information Theoretic Approach to Improving the Reliability of Weather and Climate Simulations - - - EUR 2 494 117 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The aim of this project is to develop a new synergy between climate and computer science to increase the accuracy and hence reliability of comprehensive weather and climate models. The scientific basis for this project lies in - the PI’s pioneering research on stochastic sub-grid parametrisations for climate models. These parametrisations provide estimates of irreducible uncertainty in weather and climate models, and will be used to determine where numerical precision for - model variables can be reduced without degradation. By identifying those bits that carry negligible information – typically in high-wavenumber components of the dynamical core and within parametrisation and Earth-System modules – computational - resources can be reinvested into areas (resolution, process representation, ensemble size) where they are sorely needed. This project will determine scale-dependent estimates of information content as rigorously as possible based on a variety of new - tools, which include information-theoretic diagnostics and emulators of imprecision, and in a variety of models, from idealised to comprehensive. The project will contribute significantly to the development of next-generation weather and climate - models and is well timed for the advent of exascale supercomputing where energy efficiency is paramount and where movement of bits, being the single biggest determinant of power consumption, must be minimised. The ideas will be tested on emerging - hardware capable of exploiting the benefits of mixed-precision arithmetic. A testable scientific hypothesis is presented: a proposed increase in forecast reliability arising from an increase in the forecast model’s vertical resolution, the cost being - paid for by a reduction in precision of small-scale variables. This project can be expected to provide new scientific understanding of how different scales interact in the nonlinear climate system, for example in maintaining persistent atmospheric - flow regimes. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - ITHACA - - - ERC-2016-ADG - - - 741112 - - - - - UNIVERSITA DEGLI STUDI DI MILANO - UNIVERSITA DEGLI STUDI DI MILANO - - - EUR 1 602 862 - - - Proton strucure for discovery at the Large Hadron Collider - - - EUR 1 602 862 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The objective of this project is to revolutionize the way the structure of the proton is accessed, determined, and used in the computation of physical processes at hadron colliders such as the Large Hadron Collider (LHC) of - CERN. At a hadron accelerator, predictions require a precise, detailed, and accurate description and understanding of the structure of the colliding protons, as encoded in parton distributions (PDFs) - the distributions of quarks and gluons. At the - LHC, PDFs are at present the major source of uncertainty, and in the near future they will be the main hurdle for discovery. The vision of this project is to remove this hurdle by attacking the problem using recent results from artificial - intelligence (AI). I will lead a research team of two staff scientists, four postdocs and three PhD students, who will apply to PDF determination the recent methods of deep reinforcement learning and Q-learning, which will be coupled with deep - residual networks to achieve a fully parameter- and bias-free understanding of proton structure. I will bring into high-energy physics a methodology so far used for object recognition in self-driving cars and automatic game playing, leading both to - new physics, and new computational techniques. The application of these techniques to PDFs will enable me to reach two secondary goals. The first is theoretical: the full use for PDF determination of recent high perturbative order (next-to-next-to - leading order or NNLO) computations, which will be integrated by means of a new approximation method which relies on combining known exact results with all-order information in various kinematic limits to extend the scope of the former to a more - detailed ("more exclusive") description of the final state.The second is phenomenological: the integration in PDF determination of the Monte-Carlo event generators which are used to turn field theoretical prediction into a realistic description which - may be directly compared to experimental data. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Italy - - - NNNPDF - - - ERC-2016-ADG - - - 740006 - - - - - THE HEBREW UNIVERSITY OF JERUSALEM - THE HEBREW UNIVERSITY OF JERUSALEM - - - EUR 2 026 706 - - - Complexity and Simplicity in Economic Mechanisms - - - EUR 2 026 706 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - As more and more economic activity is moving to the Internet, familiar economic mechanisms are being deployed at unprecedented scales of size, speed, and complexity. In many cases this new complexity becomes the defining - feature of the deployed economic mechanism and the quantitative difference becomes a key qualitative one. A well-studied example of such situations is how the humble single-item auction suddenly becomes a billion-times repeated online ad auction, or - even becomes a combinatorial auction with exponentially many possible outcomes. Similar complexity explosions occur with various markets, with information dissemination, with pricing structures, and with many other economic mechanisms. - - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Israel - - - COMPECON - - - ERC-2016-ADG - - - 740282 - - - - - SCUOLA NORMALE SUPERIORE - SCUOLA NORMALE SUPERIORE - - - EUR 150 000 - - - Open Correspondence Publishing and Visualization Platform. - - - EUR 150 000 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In Humanities, written correspondence is a fundamental object of study. The current IT revolution provides means for reassembling and disseminating this precious literary heritage for the first time, while at the same time - fostering new forms of scholarly cooperation. As letters create links between people, the value of documents and data increases when different corpora of written correspondences are interconnected and linked. Despite the strong need for common - standards and common tools to exploit these connections and to reconstruct the discourse of the Republic of Letters, there is still no simple framework in the current panorama for publishing digitized correspondence corpora. - - 2018-11-30, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Italy - - - OPenPal - - - ERC-2016-PoC - - - 727832 - - - - - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - - - EUR 2 000 000 - - - Epigenomic Reprogramming of Adipose Tissue Function and Energy Metabolism in Type 2 Diabetes - - - EUR 2 000 000 - - - France - France - - - Research Organisations - Research Organisations - - Obesity is associated with adipose tissue dysfunction leading to the onset of several pathologies including type 2 diabetes (T2D). The mechanisms underlying the development of obesity and T2D include the hypertrophy and/or - hyperplasia of adipocytes and adipose tissue inflammation together with an altered secretion of adipokines. However, the explanation of why individual obese (and some non-obese) humans differ in their susceptibility to develop T2D is still an issue - that is currently not sufficiently addressed. This susceptibility to T2D is mainly associated with environmental factors. One link between environment and disease is epigenetics influencing gene expression and subsequently organ dysfunction. - Epigenetic modifications in adipose tissue have been proposed to influence the susceptibility to T2D. However, the epigenomic mechanisms underpinning adipose tissue dysfunction are poorly known. In search for epigenomic modifiers that control adipose - tissue function and also impact on T2D pathogenesis, we have recently identified the transcriptional coregulators GPS2 (G-Protein Pathway Suppressor 2) and KDM6B (Histone Lysine Demethylase 6B, also called JMJD3) as strong candidates. - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - France - - - EpiFAT - - - ERC-2016-COG - - - 725790 - - - - - INSTITUT ZA FIZIKU - INSTITUT ZA FIZIKU - - - EUR 1 356 000 - - - A novel Quark-Gluon Plasma tomography tool: from jet quenching to exploring the extreme medium properties - - - EUR 1 356 000 - - - Serbia - Serbia - - - Research Organisations - Research Organisations - - Quark-Gluon Plasma (QGP) is a primordial state of matter, which consists of interacting free quarks and gluons. QGP likely existed immediately after the Big-Bang, and this extreme form of matter is today created in Little - Bangs, which are ultra-relativistic collisions of heavy nuclei at the LHC and RHIC experiments. Based on the deconfinement ideas, a gas-like behaviour of QGP was anticipated. Unexpectedly, predictions of relativistic hydrodynamics - applicable to low - momentum hadron data - indicated that QGP behaves as nearly perfect fluid, thus bringing exciting connections between the hottest (QGP) and the coldest (perfect Fermi gas) matter on Earth. However, predictions of hydrodynamical simulations are often - weakly sensitive to changes of the bulk QGP parameters. In particular, even a large increase of viscosity not far from the phase transition does not notably change the low momentum predictions; in addition, the origin of the surprisingly low - viscosity remains unclear. To understand the QGP properties, and to challenge the perfect fluid paradigm, we will develop a novel precision tomographic tool based on: i) state of the art, no free parameters, energy loss model of high momentum parton - interactions with evolving QGP, ii) simulations of QGP evolution, in which the medium parameters will be systematically varied, and the resulting temperature profiles used as inputs for the energy loss model. In a substantially novel approach, this - will allow using the data of rare high momentum particles to constrain the properties of the bulk medium. We will use this tool to: i) test our “soft-to-hard” medium hypothesis, i.e. if the bulk behaves as a nearly perfect fluid near critical - temperature Tc, and as a weakly coupled system at higher temperatures, ii) map “soft-to-hard” boundary for QGP, iii) understand the origin of the low viscosity near Tc, and iv) test if QGP is formed in small (p+p or p(d)+A) systems. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Serbia - - - QGP tomography - - - ERC-2016-COG - - - 725741 - - - - - FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA - FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA - - - EUR 2 000 000 - - - Rescuing Cognitive Deficits in Neurodevelopmental Disorders by Gene Editing in Brain Development: the Case of Down Syndrome - - - EUR 2 000 000 - - - Italy - Italy - - - Research Organisations - Chiara Andreoli - Tel.: +3901071781854 - Fax: +39 010 7170817 - Research Organisations - Chiara Andreoli - Tel.: +3901071781854 - Fax: +39 010 7170817 - - Neurodevelopmental disorders (ND) are chronic psychiatric conditions with different etiologies, but most share a strong genetic component, defective brain development, and cognitive impairment. Currently, treatment options are - very limited, and early educational intervention is the cornerstone for the management of cognitive impairment in most ND, indicating the positive effect of early actions during brain development. Among ND, Down syndrome (DS) is caused by the - presence of an extra chromosome 21, and it represents the leading cause of genetically-defined intellectual disability. Different pharmacological treatments targeting one of the many pathways downstream of the triplicated genes have been shown to - rescue cognitive impairment in DS animal models. Nevertheless, most of these preclinical studies have been performed postnatally and often in adults, possibly because of concerns of unwanted drug side effects that may have long-lasting noxious - sequelae on a developing brain at embryonic stages. On the other hand, viral (but also non-viral) gene therapy approaches in animal models of ND have been mostly neglected because of technical and ethical issues, when considered in the light of - future translational applications. Yet, DS is mostly diagnosed prenatally, when many of its brain developmental abnormalities originate. Here, we will investigate whether in utero manipulation of specific and possibly converging gene networks in - neuronal progenitors of DS mice by CRISPR-Cas9 gene-editing technology, may recover brain development and cognitive deficits later in life. Specifically targeting neuronal progenitors will allow us to act at early stages of brain development, while - avoiding the involvement of genetic editing of germline cells and all related ethical issues. In parallel, we will also develop safer (viral-free) technological approaches for genetic manipulations in utero to minimize technical issues in the view of - potential future translational applications. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Italy - - - GenEdiDS - - - ERC-2016-COG - - - 725563 - - - - - UNIVERSITEIT UTRECHT - UNIVERSITEIT UTRECHT - - - EUR 1 998 750 - - - Sharing Knowledge In Learned and Literary Networks. The Republic of Letters as a Pan-European Knowledge Society - - - EUR 1 998 750 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Most scholars today are in favour of sharing their knowledge freely, even if there is no guarantee that they will get something in return. Apparently they assume that there is some greater good involved in sharing knowledge. - Where does this ideal of knowledge come from? - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - SKILLNET - - - ERC-2016-COG - - - 724972 - - - - - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - - - EUR 1 999 740 - - - Extra-gonadal roles of Anti-Müllerian Hormone in the aetiology of polycystic ovary syndrome: the domino effect to reproductive neuroendocrine dysfunctions - - - EUR 1 999 740 - - - France - France - - - Research Organisations - Research Organisations - - Reproduction in mammals is dependent on specific neurons secreting the Gonadotropin Hormone-Releasing Hormone (GnRH). Many reproductive disorders in humans are associated with abnormal or deficient GnRH secretion. Among - reproductive dysfunctions, polycystic ovary syndrome (PCOS) is the most common form of female infertility with a prevalence of up to 10%, characterized by increased ovarian androgen biosynthesis, oligo-anovulation and frequent metabolic morbidities. - Because women with PCOS have increased luteinizing hormone (LH) pulse frequency, it has been inferred that the pulse frequency of GnRH must be accelerated as well. However, so far PCOS has been considered mainly as a gonadal pathology and possible - regulations from the central nervous system or interactions with it remain elusive. In patients with PCOS, ovarian levels of Anti-Mullerian Hormone (AMH) are also elevated, indicating the potential relevance of AMH for PCOS diagnosis and management. - Recently, we showed that AMH acts directly on GnRH neurons to increase neuropeptide secretion, raising the intriguing hypothesis that AMH-dependent regulation of GnRH release could be involved in the neuroendocrine control of fertility and - pathophysiology of PCOS. By providing integrative, functional and mechanistic in vivo strategies, combined with clinical human investigations, REPRODAMH will represent a major step forward into the understanding of PCOS with the final goal of - developing new therapeutic strategies. To achieve these goals we will: - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - France - - - REPRODAMH - - - ERC-2016-COG - - - 725149 - - - - - RUHR-UNIVERSITAET BOCHUM - RUHR-UNIVERSITAET BOCHUM - - - EUR 1 483 092,50 - - - Protection of Redox Catalysts for Cathodic Processes in Redox Matrices. - - - EUR 1 483 092,50 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Biological or molecular catalysts built from Earth-abundant elements are envisioned as economically viable alternatives to the scarce noble metals that are currently used in renewable energy conversion. However, their - fragility and O2 sensitivity have been obstacles to their adoption in industry. We have recently proposed O2 quenching matrices for protecting intrinsically O2-sensitive catalysts for use in anodic (oxidative) processes. We have demonstrated that - even hydrogenases, the highly sensitive metalloenzymes that oxidize H2, can be used under the harsh conditions encountered in operating fuel cells. However, attempts to reverse the concept for the protection of cathodic (reductive) processes, such as - H2 evolution, have been unsuccessful so far. In this case, the electrode generates the reducing agents in the form of electrons, which are needed for both H2 generation and reductive O2 quenching. The competition between the two reactions results in - insufficient protection from O2 and deactivation of the catalyst. - - 2022-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - REDOX SHIELDS - - - ERC-2016-STG - - - 715900 - - - - - RUHR-UNIVERSITAET BOCHUM - RUHR-UNIVERSITAET BOCHUM - - - EUR 2 000 000 - - - In situ and Operando Nanocatalysis: Size, Shape and Chemical State Effects - - - EUR 2 000 000 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Tailoring the chemical reactivity of nanomaterials at the atomic level is one of the most important challenges in catalysis research. In order to achieve this elusive goal, fundamental understanding of the structural and - chemical properties of these complex systems must be obtained. Numerous studies have been devoted to understanding the properties that affect the catalytic performance of metal nanoparticles (NPs) such as their size, interaction with the support, and - chemical state. The role played by the NP shape on catalytic performance is, however, less understood. Complicating the analysis is the fact that the former parameters cannot be considered independently, since the NP size as well as the support will - have an impact on the most stable NP shapes. In addition, the dynamic nature of the NP catalysts and their response to the environment must be taken into consideration, since the working state of a NP catalyst might not be the state in which the - catalyst was prepared, but rather a structural and/or chemical isomer that adapted to the particular reaction conditions. To address the complexity of real-world catalysts, a synergistic approach taking advantage of a variety of cutting-edge - experimental methods must be undertaken. - - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - OPERANDOCAT - - - ERC-2016-COG - - - 725915 - - - - - HELSINGIN YLIOPISTO - HELSINGIN YLIOPISTO - - - EUR 1 972 905 - - - Elucidation of intratumoral heterogeneity in Kras-driven cancers - - - EUR 1 972 905 - - - Finland - Finland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The considerable variability within tissue microenvironments as well as the multiclonality of cancers leads to intratumoral heterogeneity. This increases the probablility of cellular states that promote resistance to therapy - and eventually lead to reconstitution of the tumor by treatment-resistant cancer cells, which in some cases have properties of normal tissue stem cells. Wnt signals are important in the maintenance of stem cells in various epithelial tissues, - including in lung development and regeneration. We hypothesized that Wnt signals contribute to tumor heterogeneity in genetically engineered KrasG12D; Tp53Δ/Δ (”KP”) mouse lung adenocarcinomas (LUAD). We observed that a subpopulation of LUAD cells - exhibited high Wnt reporter activity and had increased tumor forming ability, which could be suppressed by silencing of Wnt signaling pathway components or by small molecule Wnt inhibitors in vitro and in vivo. KP LUAD cells show hierarchical - features with two distinct populations, one with increased Wnt reporter activity and another forming a niche that provides the Wnt signal. Lineage-tracing experiments in the autochthonous KP tumors demonstrated that Wnt responder cells have increased - tumor propagation ability in vivo. Strikingly, selective ablation of the Wnt responder cells resulted in tumor stasis. CRISPR-based targeting or small molecules targeting Wnt signaling reduced tumor growth and prolonged survival in the autochthonous - KP mouse lung cancer model. These results indicate that maintenance of heterogeneity within tumors may be advantageous for the tumor cell population collectively. We propose to elucidate the molecular and cellullar mechanisms that control stem-like - and niche cell phenotypes using a combination of novel lentiviral vectors and genetically modified mice in the context of the KP LUAD model. These efforts may lead to novel therapeutic concepts in human lung cancer. - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Finland - - - INTUMORX - - - ERC-2016-STG - - - 716162 - - - - - KARLSRUHER INSTITUT FUER TECHNOLOGIE - KARLSRUHER INSTITUT FUER TECHNOLOGIE - - - EUR 2 335 416,25 - - - Molecular Quantum Opto-Spintronics - - - EUR 2 335 416,25 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The field of quantum materials has developed into an active playground for testing novel ideas and protocols for future devices governed by the principles of quantum mechanics. Quantum technologies might result in - revolutionary improvements in terms of capacity, sensitivity, and speed, and will be the decisive factor for success in many industries and markets (http://qurope.eu/manifesto). - - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - MoQuOS - - - ERC-2016-ADG - - - 741276 - - - - - LIBERA UNIVERSITA DI BOLZANO - TECHNICKA UNIVERZITA V KOSICIACH - MONTANUNIVERSITAT LEOBEN - ELCOM, SPOLOCNOST S RUCENIM OBMEDZENYM, PRESOV - CHIANG MAI UNIVERSITY - MASSACHUSETTS INSTITUTE OF TECHNOLOGY - WORCESTER POLYTECHNIC INSTITUTE - MADURAI AYIRA VAISYAR MANJAPUTHUR MAHAJANA SABAI - - - EUR 783 000 - - - Industry 4.0 for SMEs - Smart Manufacturing and Logistics for SMEs in an X-to-order and Mass Customization Environment - - - EUR 954 000 - - - Italy - Slovakia - Austria - Slovakia - Thailand - United States - United States - India - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - Industry 4.0 refers to the fourth industrial revolution and technological evolution from embedded systems to cyber-physical systems (CPS) in production. The main objectives of Industry 4.0 can be summarized as the introduction - of intelligent systems in production and logistics, the development of highly adaptable and modular manufacturing and logistics systems, the integration of sustainable and advanced manufacturing technologies as well as the promotion of automation - technology and human-machine interaction. In the context of Industry 4.0 new ICT and web technologies act as booster or enabler of smart, autonomous and self-learning factories facing the challenges of even more individualized and customized product - portfolio. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Italy - - - SME 4.0 - - - H2020-MSCA-RISE-2016 - - - 734713 - - - - - UNIVERSITAET MANNHEIM - UNIVERSITAET MANNHEIM - - - EUR 1 212 934 - - - Illicit Markets, Unobserved Competitors, and Illegal Behavior - - - EUR 1 212 934 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Many markets are characterized by illicit or illegal behavior by agents. To the extent that the empirical economic framework does not incorporate these unobserved actions or control for them in estimation, the resulting models - are likely to be mis-specified. Naturally, if the models do not contain all elements relevant for decision making, then predictions based on the estimates will be misleading, which could result in incorrect policy recommendations. This project - directly addresses three situations in which unobserved behavior plays a crucial role. The first concerns markets where consumers engage in illicit behavior. These markets are prevalent in society as they constitute the market for illicit drugs, - which is estimated at more than $300 billion per year (UN, 2012). The second concerns markets where firms make strategic decisions in the presence of an unidentified competitor - a counterfeiter, where the global value of counterfeit products rivals - that of illegal drugs (OECD, 2007). The third concerns situations where firms use legal tools for illegal purposes, for which the impact is challenging to quantify and one goal of this project. In each area, the project (i) develops state-of-the-art - empirical models that incorporate illicit behaviors, (ii) proposes novel estimation methods that can be used to detect illegal behavior, and (iii) provides evidence that the proposed methodology is feasible and the data are sufficient to estimate the - models. Incorporating and estimating unobserved behavior in a variety of settings is an ambitious undertaking. However, it is vital as a key objective of the proposal is to provide policy makers with tangible tools that accurately reflect the - unobserved nature of these markets. Given the global significance of illicit markets, the novel concepts proposed, and the focus on policy, this project has the potential to make a sizable impact, both in and beyond academia, representing an - ambitious but worthwhile pursuit. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - FORENSICS - - - ERC-2016-COG - - - 725081 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 171 792,60 - - - Electrophilic-induced asymmetric boronate rearrangements via CAPT catalysis. A novel approach towards the formal trifunctionalization of alkenes. - - - EUR 171 792,60 - - - United Kingdom - - - Higher or Secondary Education Establishments - - This proposal describes an unprecedented, enantioselective haloborylation reaction through the innovative application of chiral anion phase-transfer (CAPT) catalysis to electrophilic-induced boronate rearrangements. Beyond the - development of an orthogonal approach towards the formal trifunctionalization of alkenes, the proposed methodology provides easy access to biologically and synthetically important products, and is anticipated to have great impact in the area of - diversity oriented synthesis. - - 2019-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - HALOBORYLATION - - - H2020-MSCA-IF-2016 - - - 744604 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 2 000 000 - - - Smart Multimodal Microscopy for High-Throughput Developmental Biology in Real-Time - - - EUR 2 000 000 - - - Germany - Germany - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - "Fluorescence microscopy is a key technology in our quest to understand fundamental developmental processes of life. High-resolution images recorded in intact, living organisms deliver insights into the complex interplay of - molecules, cells and tissues in real time. Even though the resolution of microscopes has been pushed beyond the diffraction limit, providing important insights into the inner workings of single cells, we still lack an understanding of plasticity in - development: How does one embryo differ from another and how can we describe the "average", stereotypic embryo? - - 2020-06-30, Grant Agreement terminated - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - SmartMic - - - ERC-2014-CoG - - - 647885 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 195 454,80 - - - Increasingly Anthropogenic Landscapes and the Evolution of Plant-Food Production: Human - Environment Interactions during the Final Pleistocene and Early Holocene in the Levant. - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - H-E Interactions will investigate how increasingly anthropogenic wetland landscapes and the reliable resources therein influenced the evolution of plant-food production and the origins of agriculture through the Final - Pleistocene into the Early Holocene (ca.23-8 ka cal. BP). It will consider how earlier human-environment interactions shaped this key transition, integrating the latest theoretical Human Niche Construction (HNC) perspectives with environmental - archaeology to investigate 5 well-excavated wetland oriented archaeological sites in the S. Levant. It will employ an interdisciplinary, combination of microbotanical approaches, (phytolith, starch and microcharcoal analyses) and geoarchaeology, in - particular micromorphology, to investigate the on- and off-site contexts of a temporally broad set of sites to provide long-term, direct evidence of ancient plant-use. To achieve this, training in geoarchaeology, GIS and multivariate statistical - skills will facilitate the production, management and interpretation of the large environmental dataset. As well as providing direct evidence of plant-use and environment from a critical H-E threshold, H-E Interactions is the first study in the - region to directly examine how HNC practices impacted the origins of agriculture. So far, the origin of agriculture has been largely understood as a consequence of human reactions to environmental push & pull factors. This project presents an - alternative approach and takes the view that increased use of ‘low-ranked’ resources may reflect deliberate human modification, management and/or food processing innovation, increasing the relative abundance and ease of acquisition of ‘low-ranked’ - resources, resulting in ‘upward mobility’ of that resource. HNC provides a new way to consider changing plant resource selection in the Levant and the wider cultural and environmental implications, which may have impacted the rise of increasingly - sedentary lifestyles and the origins of agriculture. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - H-E Interactions - - - H2020-MSCA-IF-2016 - - - 743544 - - - - - UNIVERSITEIT LEIDEN - UNIVERSITEIT LEIDEN - - - EUR 1 499 578 - - - The Linguistic Roots of Europe's Agricultural Transition - - - EUR 1 499 578 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Today, Europe’s linguistic landscape is shaped almost entirely by a single language family: Indo-European. Even by the dawn of history, a patchwork of Indo-European subgroups, Germanic, Celtic, Italic, Baltic, Slavic and - Greek, was covering the continent, and over the centuries, these subgroups evolved into the modern European languages, among which Russian, Italian, German, Lithuanian and Swedish, as well as the global lingua francas French, Spanish, and English. - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - EUROLITHIC - - - ERC-2016-STG - - - 716732 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 2 038 120 - - - ConfocAl Microscopy and real-time Rheology of dynamIc hyroGels - - - EUR 2 038 120 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Hydrogels cross-linked through supramolecular interactions are highly dependant on the dynamic charac- teristics of the physical cross-links. Few fundamental studies have been undertaken to quantitatively de- scribe - structure-property relationships for these types of systems. Hydrogels formed from CB[8]-mediated supramolecular physical cross-linking mechanisms have gained significant interest on account of their excel- lent physical and mechanical properties - such as self-healing and shear-thinning. This supramolecular motif has been further exploited to introduce and compatibilise a wide variety of different materials into hydrogel networks without phase separation, forming hybrid composite hydrogels - attributed with unique and emergent properties. This proposal aims to pioneer the combination of several state-of-the-art characterisation tech- niques into an unique experimental setup (CAM-RIG), which will combine super-resolution and confocal - microscopy imaging modalities with simultaneous strain-controlled rheological measurements to investigate fundamental structure-property relationships of these systems. For the first time it will be possible to decon- volute the molecular-level - dynamics of the supramolecular physical cross-links from chain entanglement of the polymeric networks and understand their relative contributions on the resultant properties of the hydrogels. Using the fundamental insight gained, a set of key - parameters will be determined to maximise the potential of supramolecular biocompatible hydrogels, driving paradigm shifts in sustainable science and biomaterial applications through the precise tuning of physical properties. - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - CAM-RIG - - - ERC-2016-COG - - - 726470 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 183 454,80 - - - A droplet microfluidic system for continuous in vivo evolution. - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Droplet microfluidics has recently become one of the breakthrough technologies for high throughput screening in microbiology and biochemistry, including single cell studies and new approaches to in vitro evolution. Here we - propose a development of a novel microfluidic system for unsupervised execution of multiple cycles of in vivo continuous evolution in hundreds of thousands of picoliter droplets. Each evolutionary cycle will comprise: i) encapsulation of single - bacteria cells in water-in-oil compartments ii) growth of the cells coupled with production of economically relevant biomolecules iii) selection of the most efficient populations using ultra-high-throughput sorting of picodroplets, iv) dilution of - each population via merging with 100 times larger nanoliter droplet containing fresh nutrients and v) passive splitting of each of the resulting nanoliter droplets to the libraries of picoliter droplets containing single cells. Confinement of the - reaction in small volume and active sorting of droplets will facilitate and accelerate the process of in vivo evolution. Droplet format will also enable for various screening schemes, so far not available for continuous evolution strategies – e.g. - based on high throughput fluorescence or absorbance measurements of the droplet content. The second stage of the project will comprise a series of proof-of-concept experiments presenting directed continuous evolution of the tryptophan synthase (TrpS) - in E.coli bacteria. The technology proposed here would be very useful for broad community of biotechnologists, evolutionary biologists and industrial specialists without the experience in microfluidics. The proposed research will be conducted at Dr. - Hollfelder´s laboratory that specializes in directed evolution of enzymes and application of microfluidics to industrial biotechnology. The project comprise broad and extensive training in research and complementary soft skills that will aid - professional development of the Beneficiary. - - 2019-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - DropContEvo - - - H2020-MSCA-IF-2016 - - - 750772 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 183 454,80 - - - Development of a model system to study the role of chromatin factors during transgenerational epigenetic inheritance (TEI) in C. elegans - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Non DNA-sequence based inheritance has been observed in many organisms from microbes to man and likely impacts public health. The mechanisms of non DNA-sequence based inheritance remain largely unknown. However, some examples - of non DNA-sequence based inheritance in mammals, plants and invertebrates are linked to the control of selfish, transposable elements in the genome. Here we propose to discover the mechanistic basis of multi-generational non DNA-sequence based - inheritance, also referred to as transgenerational epigenetic inheritance (TEI), using the laboratory animal model Caenorhabditis elegans. Specifically, our goal is to identify chromatin and non-coding RNA “epigenetic” marks that transfer information - from generation to generation in C. elegans. C. elegans is a great model for this work as it has a generation time of only three days, has a powerful genetics toolkit and its chromatin and RNA pathways are largely conserved in humans. Towards this - goal we have established a novel assay we named piRNA-related insertional chromatin immunoprecipitation (piChIP). Using this piChIP system, our specific aims are: - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - TEI - - - H2020-MSCA-IF-2016 - - - 747666 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 1 996 250 - - - ARCTIC CULTURES: SITES OF COLLECTION IN THE FORMATION OF THE EUROPEAN AND AMERICAN NORTHLANDS - - - EUR 1 996 250 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The Arctic has risen to global attention in recent years, as it has been reconfigured through debates about global environmental change, resource extraction and disputes over sovereign rights. Within these discourses, little - attention has been paid to the cultures of the Arctic. Indeed, it often seems as if the Circumpolar Arctic in global public understanding remains framed as a 'natural region' - that is, a place where the environment dominates the creation of culture. - This framing has consequences for the region, because through this the Arctic becomes constructed as a space where people are absent. This proposal aims to discover how and why this might be so. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - ARCTIC CULT - - - ERC-2016-COG - - - 724317 - - - - - UNIVERSITY OF YORK - UNIVERSITY OF YORK - - - EUR 1 989 611 - - - The evolutionary and developmental origins of Joint Attention: a longitudinal cross-species and cross-cultural comparison - - - EUR 1 989 611 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Humans frequently coordinate and share attention about objects and events. Our basic ability to engage in joint attention (JA) is thought to underpin our uniquely complex cooperation skills and language, raising the - possibility that the emergence of JA was a ‘small change that made a big difference’ in the evolution of human cognition. Despite the theoretical importance of JA for understanding human social cognition, we know surprisingly little about JA across - species and cultures. Methodological shortcomings limit our understanding of the extent to which JA is uniquely human or shared with our primate cousins, and we lack data on how this ability develops in non-western cultures, which aspects of the - social environment are necessary for JA to emerge and how JA is related to the emergence of cooperation. The JOINTATT project will address these four key issues by collecting longitudinal data on mother-infant dyads over the first 2 years of the - infant’s life, across four different study groups: Ugandan and British humans; wild chimpanzees and crested macaque monkeys. The project will develop novel tasks and measures that allow the same set of data to be collected in directly comparable ways - across species and provide the first valid, rigorous test of whether engagement in JA is a uniquely human trait. Data from the two human groups will test how different elements of JA are related and whether JA develops in a uniform way across - cultures. Longitudinal data on mother-infant interactions and the infant’s environment will be related to performance on JA tasks across all four groups, enabling us to identify conditions that are likely necessary for JA to emerge. Performance on JA - and cooperative tasks will be compared to assess whether engagement in JA predicts the later emergence of cooperation. This project will provide ground-breaking insights into JA and its evolutionary origins, and is likely to challenge current - theories of how human social cognition evolved. - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - JOINTATT - - - ERC-2016-COG - - - 724608 - - - - - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - - - EUR 171 460,80 - - - Disentangling amygdala contributions to replay-mediated, hippocampal-dependent memory consolidation - - - EUR 171 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - In today’s societies, adequate rest takes second place to busy professional and personal schedules. It is known that lack of rest and sleep affects mental health, emotional regulation and daytime function. Such symptoms - translate to increased healthcare costs and losses in workplace productivity. How emotional regulation processes interact with sleep and associated memory consolidation functions is not well understood. In addition to increasing basic understanding - of brain function, addressing this knowledge gap can help shape therapeutic approaches for mental wellbeing and contribute to EU’s H2020 goals of smart, sustainable and growth. - - - 2019-10-14, ongoing project - - - 2017-10-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - VALENCE-REPLAY - - - H2020-MSCA-IF-2016 - - - 746778 - - - - - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - - - EUR 146 130 - - - A clinical phonetics laboratory service (PhonLab): diagnostics of speech impairment via the web - - - EUR 146 130 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In line with present trends to expand eHealth in medical care, this project‘s objective is to provide a commercial web-based service for the automatic diagnosis of impaired speech, given a sample of the client’s speech - transmitted over the internet. Currently, speech therapists are required to diagnose speech impairments from only a pen and paper analysis of transcriptions based on auditory impressions. The main advantage of the innovative approach of this project - is to quantify the production of speech in time according to the scientific state of the art, which is well beyond the scope of presently used impressionistic, auditory techniques. - - - 2018-11-30, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Germany - - - PhonLab - - - ERC-2016-PoC - - - 737552 - - - - - STICHTING KATHOLIEKE UNIVERSITEIT - STICHTING KATHOLIEKE UNIVERSITEIT - - - EUR 2 498 076 - - - Encoding information into polymers - - - EUR 2 498 076 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The amount of information trafficking internet nowadays is enormous and will increase further in the near future. It can be expected that in the next decennia the current technologies to store and process data will no longer - suffice and that other strategies to handle information have to be developed. One approach is to explore chemical routes, which nature has also followed during evolution: our brain can store and handle very large amounts of data and process them in a - way silicon-based computers cannot do. Although brain-like chemical computers are still far beyond reach, it is of interest to explore how atom and molecule-based systems that can write, read, and store information might be designed and constructed. - In this proposal we aim at developing a new technology to write, store, and read information, i.e. on a single polymer chain with the help of a molecular machine that is inspired by the hypothetical device (Turing machine) proposed by the British - mathematician Alan Turing in 1936 as the general basis for the operation of a computer. The molecular machine is composed of a chiral catalytic cage compound (tape-head) that moves unidirectionally along a chiral polymer chain (tape) while writing a - binary code in the form of (R)- (symbol 0) and (S)- (symbol 1) epoxide functions. This writing process is controlled by light or electrons. The information on the tape will be read by single molecule spectroscopy using a reading device that is also - based on a chiral cage compound. It moves along the encoded tape and produces left- or right-handed polarized fluorescence light depending on whether it reads a 0 (R-epoxide) or 1 (S-epoxide). As part of this project we will also make the first steps - towards chemical computing by arranging two circular tapes (one left-handed and the other one right-handed), each with an attached writing head, in a teller set-up, which allows them to be addressed separately with light according to a set of - instructions (Minsky machine). - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Netherlands - - - ENCOPOL - - - ERC-2016-ADG - - - 740295 - - - - - UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN - UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN - - - EUR 1 997 132 - - - Labour Politics and the EU's New Economic Governance Regime - - - EUR 1 997 132 - - - Ireland - Ireland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Trade unions play a major role in democratic interest intermediation. This role is currently threatened by the increasingly authoritarian strain in EU’s new economic governance (NEG). This project aims to explore the - challenges and possibilities that the NEG poses to labour politics. Until recently, European labour politics has mainly been shaped by horizontal market integration through the free movement of goods, capital, services and people. After the financial - crisis, the latter has been complemented by vertical integration effected through the direct surveillance of member states. The resulting NEG opens contradictory possibilities for labour movements in Europe. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Ireland - - - European Unions - - - ERC-2016-COG - - - 725240 - - - - - UNIVERSITY OF SOUTHAMPTON - - - EUR 257 017,35 - - - Developing methods to model local area temporal domestic electricity demand - - - EUR 257 017,35 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The objective of this proposal is to implement a programme of research and impact activities intended to provide a step change in the level of understanding of, and modelling capacity for, spatially disaggregated temporal - domestic electricity demand in a smart grid and demand response context. This programme will be developed in partnership with internationally recognised experts led by the University of Otago (host) who are pioneering in this field. It will be - exploited via an applied research programme at the University of Southampton (beneficiary) which intends to integrate census, social science time use and detailed consumption data to develop local area level demand response models to support the - analysis of a range of demand response scenarios. In so doing the fellowship will provide the applicant with a foundation from which to build a new career pathway by applying his substantial existing social scientific data analysis and spatial - microsimulation expertise to the development and leadership of a substantial new European research capacity in an area of emerging commercial, societal and political significance. - - 2020-10-31, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - Spatialec - - - H2020-MSCA-IF-2015 - - - 700386 - - - - - STICHTING KATHOLIEKE UNIVERSITEIT - - - EUR 242 929,80 - - - A Cross-Species Investigation of Memory Replay During Reconsolidation - - - EUR 242 929,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - A primary treatment for anxiety disorders is exposure therapy, which is based on the principles of extinction, but has the drawback that fear can return. This risk of relapse highlights a need for treatments that persist. - Research on reconsolidation has shown that upon reactivation old fear memories can be updated, preventing the return of fear. However, studies targeting reconsolidation to reduce fear have reported mixed results because its boundary conditions are - poorly understood. To live up to its clinical potential it is necessary to understand how to most effectively utilize paradigms targeting reconsolidation. The proposed research attempts to address this issue by providing a neural measure of the - reconsolidation process itself. This will be achieved by determining whether dynamic patterns of neural network activity that occur during initial learning re-occur during offline ‘rest’ periods, and test whether this ‘replay’ of memory is linked to - reconsolidation. The first objective of this grant application is to identify and quantify a neural marker of reconsolidation that predicts the absence of fear recovery. During the outgoing phase these questions will be addressed employing an - innovative cross-species (humans, rats) approach using similar behavioural tasks, complementary recording techniques (functional magnetic resonance imaging, multi-unit recordings) and state-of-the-art analyses methods. Acquired knowledge and - experience will be applied during the return phase where the second objective is to use this neural marker to determine how context serves as one critical boundary condition to inducing reconsolidation. Findings will significantly advance fundamental - understanding of reconsolidation and have important implication for applied and preclinical psychiatric research. - - 2018-05-31, ongoing project | - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Netherlands - - - ReconsolidationDynamics - - - H2020-MSCA-IF-2014 - - - 659221 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 195 454,80 - - - The Remote Control of Maternal Metabolism by the Placenta - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - During pregnancy many physiological changes occur in the mother that are designed to support fetal growth. These include changes in the cardiovascular, pulmonary, immune and metabolic systems. In particular, the mother becomes - less reactive to insulin, leading to increased glucose availability to the fetus in late pregnancy. These adaptations are thought to be signaled, in part by changes in placental hormone production. Whilst studies have shown that the placenta has the - capacity to produce different hormones, their specific role in adapting maternal metabolism during pregnancy relies principally on association studies. Moreover, there are likely to be more protein mediators secreted by the placenta with systemic - actions in the mother. Failure to adjust the mother's body to the pregnant state may result in pregnancy complications, including abnormal birth weight and maternal diabetes, which can further lead to a range of medical complications for the mother - and baby. The overall goal of this study will be to identify the nature and wider biological significance of placental endocrine function in adapting the mother's body during pregnancy to support fetal growth, with a focus on maternal metabolism. - This work will primarily use the mouse as an experimental model as the placental signaling/secreting cells are conveniently organized into a distinct region and are under unique genetic control. Therefore placental signaling cells can be isolated, - cultured and genetically-modified independent of other cells in the mouse placenta. The secreted placental candidates will be identified using the latest sequencing technologies, and their metabolic effects will be tested on cell lines and in the - whole organism using unique genetic tools available at the University of Cambridge. Knowledge gained from this study will be the first step in the development of targeted interventions for optimizing fetal growth and preventing pregnancy - complications. - - 2018-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - PlaEndo - - - H2020-MSCA-IF-2015 - - - 703160 - - - - - FUNDACIO INSTITUT D'INVESTIGACIO SANITARIA PERE VIRGILI (IISPV) - - - EUR 257 191,20 - - - Interplay between genetic determinants of glycaemia, type 2 diabetes and cardiovascular disease in interaction with dietary and lifestyle factors - - - EUR 257 191,20 - - - Spain - - - Research Organisations - - Genome-wide association studies (GWAS) for complex traits, including glycaemia, type 2 diabetes (T2D) and coronary heart disease (CHD) have been successful in identifying genetic variants associated with those phenotypes. - However, they explained only a small proportion of the estimated heritability. Possible reasons include the interplay between genetics and lifestyle determinants, small-effect variants, structural variations and the difficult to characterize - non-coding functional variants that interact with other genetic regions. This proposal, in a new era of precision medicine, englobes the systematic study of the interplay between genetic variants associated with glycaemia, T2D, CHD and dietary and - lifestyle factors. We propose to conduct a comprehensive analysis of gene and gene-lifestyle interaction, including the existing international GWAS consortia of CARDIoGRAM, DIAGRAM, MAGIC, the U.S. based DPP clinical trial, and the European-wide - networks of EPIC-InterAct and PREDIMED. We will test hypothesis about: 1) whether genetically driven hyperglycaemia increases risk of CHD, 2) the association between genetic determinants of CHD and intermediate metabolic phenotypes, and 3) whether - dietary components and lifestyle changes influence these associations. Finally, we will extend and replicate these previous results in two independent populations, and to deploy a new method to identify implicated biological pathways. Information - that will emerge from that project will provide valuable insights into missing heritability for T2D and CHD. Specifically we expect to uncover genetic determinants for faster CHD progression in T2D, identifying vulnerable individuals who are more - likely to experience a differential response to current prevention strategies and to validate potential targets and avenues for intervention. The experienced researcher will emerged from the project with new skills, and the capability to launch his - own research group in Europe. - - 2020-02-17, ongoing project - - - 2017-02-18 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Spain - - - INTERPLAY - - - H2020-MSCA-IF-2015 - - - 703787 - - - - - Barcelonabeta Brain Research Center Foundation - - - EUR 158 121,60 - - - Multiregional rtfMRI Neurofeedback for the Prevention of Alzheimer's Disease - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - This project aims at predicting early cognitive decline using a neurofeedback performance endophenotype based on realtime functional magnetic resonance imaging in a population at risk for Alzheimer’s Disease (AD). It has been - proven that AD biomarkers change decades before the development of symptoms. In addition, there is a lack of robust hypersensitive methods capable of predicting impending cognitive decline in healthy subjects at risk. This constitutes a crucial - obstacle for the implementation of AD prevention trials. To address this, we will identify and characterize a novel neurofeedback performance endophenotype in a subsample from a cohort of 2743 cognitively healthy volunteers at risk for AD. This will - be based on state-of-the-art neuroimaging technology, in combination with a novel sensitive neuropsychological test that detects subtle alterations in episodic memory, which has been validated for our cohort. Then, we will evaluate the impact on our - newly developed neurofeedback performance endophenotype of factors known to be related to AD such as various clinical and lifestyle variables, amyloid deposition, genetic background (including, but not restricted to APOE4) and most importantly - cognitive reserve. A specific aim is to test the hypothesis that neurofeedback performance can become a reliable proxy to measure cognitive reserve. Finally, we will develop a novel statistical predictive model, featuring all the relevant genetic and - clinical variables and will assess the capacity of neurofeedback performance for predicting impending cognitive decline during a two-year period in AD descendants. - - 2018-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - NPAD - - - H2020-MSCA-IF-2015 - - - 707730 - - - - - SENSARS NEUROPROSTHETICS SARL - - - EUR 99 912,50 - - - Restoring of SENSAtions from Lost LeGs for health And qualIty of life augmeNtation in amputees - - - EUR 99 912,50 - - - Switzerland - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - During the FET NEBIAS we developed and clinically validated novel and effective restoration of sensory feedback from missing hand in upper-limb amputees. They felt natural sensations, used to ameliorate control and acceptance - of prosthesis, and diminish phantom limb pain. The goal of SensAgain is to exploit these results commercially. In particular, we aim at verifying whether the innovation generated during NEBIAS could be used to provide valuable device for lower-limb - amputees. We target them because they represent a larger population and suffer health problems related to absence of sensations from prosthesis. Indeed, because of the lack of sensory feedback from available prostheses, they suffer: falls due to - unexpected perturbations, asymmetric walking and balance which induce arthritis, osteoporosis and back pain, higher power consumption (with occasional hearth failures), feeling the prosthesis as a foreign body (with consequent abandonment) and - phantom pain. The first step we will perform is the validation with market stakeholders, which will enable the identification of the minimum features of a product accepted by the market, and the development of a strategic partnership with - manufacturers, which will speed up the realization of a device compliant with CE standards. Then, we will define a clear market penetration strategy. Together with providing disabled persons with a unique device for rehabilitation, SensAgain will - boost prosthetic adoption, with the consequent growth of the prosthetics and rehabilitation industries, which at its turn will create new jobs. Finally, by sharing the results with the members of the NEBIAS consortium, we will train academia - personnel to structure their research mind-set toward the resolution of problems tailored by the market needs. On the other hand we will favor the process of creating innovation in industry, offering job positions to people with a background in - research, in case of success of our translational project. - - 2019-02-28, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-04-2016-2017 - FET Innovation Launchpad - - - CSA - Coordination and support action - - - Switzerland - - - SensAgain - - - H2020-FETOPEN-4-2016-2017 - - - 754497 - - - - - GRAN SASSO SCIENCE INSTITUTE - - - EUR 180 277,20 - - - Galactic cosmic RAy Propagation: an Extensive Study - - - EUR 180 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - Where do Cosmic Rays (CRs) originate? How do CRs interact with the environment during their journey to Earth? - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - GRAPES - - - H2020-MSCA-IF-2016 - - - 751311 - - - - - UNIVERSITE GRENOBLE ALPES - UNIVERSITE GRENOBLE ALPES - - - EUR 2 454 367,50 - - - The Dawn of Organic Chemistry - - - EUR 2 454 367,50 - - - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Terrestrial life is based on organic chemistry, on the complex combination of relatively small molecules containing less than 50 atoms of carbon and other elements in smaller quantities. Some of these bricks, notably amino - acids, are found in meteoritic and cometary material, a fact (among others) which led the Nobel laureate C. de Duve to conclude that “the seeds of life are universal” and “life is an obligatory manifestation of matter, written into the fabric of the - Universe”. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - France - - - DOC - - - ERC-2016-ADG - - - 741002 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 185 076 - - - Rational design of novel heterometallic MOFs for their use in heterogeneous catalysis for cascade reactions - - - EUR 185 076 - - - France - - - Research Organisations - - "The field of metal-organic frameworks (MOFs) is currently among the most extensively studied topics in chemistry given the large number of fascinating applications associated with the chemical versatility of MOFs. In - particular, the use of MOFs as heterogeneous catalysts is an area that has attracted considerable attention since, in principle, the ideally suited architectures of MOFs can present catalytically active sites spatially arranged. With the expansion of - this area, a new emergent class of heterometallic metal-organic frameworks (hetero-MOFs) has recently been considered for the study of an important type of reactions from an industrial point of view in which two or more individual reactions are - carried out in a single step ("tandem" or "cascade" reactions). However, the synthetic approach for the preparation of these hetero-MOFs has been mainly conducted by post-synthetic replacement of ions with the same oxidation state, with lack of - control over the final composition. - - 2017-04-30, closed project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - hetero-MOF - - - H2020-MSCA-IF-2014 - - - 658224 - - - - - UNIVERSITA CA' FOSCARI VENEZIA - - - EUR 250 518,60 - - - Shifting Dynamics of Chinese Labour in a Global Perspective - - - EUR 250 518,60 - - - Italy - - - Higher or Secondary Education Establishments - - With the financial crisis stepping up the pressure on labour regimes around Europe, and with the European national economies increasingly subject to the vagaries of an uncertain Chinese growth, questions traditionally of - interest only to Chinese labour specialists and rights advocates are taking a whole new dimension. Chinese labour issues have ceased to be local matters and have assumed a particular urgency, entering much of the political rhetoric of the European - countries. Such diffused presence of Chinese labour in the European imaginary raises many questions and requires a thorough investigation. In particular, in the past few years, much has been written about a “rights awakening” allegedly undergoing - among internal migrant workers in China. But how do Chinese workers perceive their rights? What role do Chinese state and non-state actors play in shaping this perception? And, more important, how will these shifting dynamics of Chinese labour - activism affect the future of China as a “world factory”? Research that answers these questions is still scarce. The purpose of this study is threefold: a) analyse the expectations of Chinese migrant workers toward work hours and salaries, on the - background of the minimum standards mandated by the current labour legislation; b) deconstruct the role played by different actors in shaping these expectation, with a particular attention to the role of the central and local state, the union, civil - society organizations and foreign enterprises; c) address the implications of the rising expectations of the Chinese workers for EU investments in China and for the future of the country as a “world factory”. This research will not only give a - meaningful contribution to the academic debate, but will also provide European policy-makers, companies, trade unions and labour NGOs with much needed knowledge on how to address Chinese labour issues in this new phase of the globalization process. - - 2018-12-14, ongoing project - - - 2015-12-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Italy - - - Chinese Labour - - - H2020-MSCA-IF-2014 - - - 654852 - - - - - LUNDS UNIVERSITET - LUNDS UNIVERSITET - - - EUR 2 498 625 - - - Hunting for the elusive “sixth” sense: navigation and magnetic sensation in a nocturnal migratory moth - - - EUR 2 498 625 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Many animals – including birds, sea turtles and insects – perform spectacular long-distance migrations across the surface of the Earth. Remarkably some, like birds, can accurately migrate between highly specific locations - thousands of kilometres apart, a navigational feat that requires an external compass cue and a robust sensory system to detect it. The Earth’s magnetic field is one such compass cue. But exactly how the magnetic field is sensed, and which receptor - cells are involved, remains a mystery and its discovery is one of the greatest “holy grails” in modern sensory physiology, and also the main aim of this proposal. Fortuitously, I have made a pioneering discovery that a migratory insect – the - Australian Bogong moth – relies on the Earth’s magnetic field to navigate at night. Due to its tractable nervous system, this insect may thus hold the key to uncovering the identity of the enigmatic magnetosensor. By tethering flying migrating moths - in a flight simulator, I will dissect for the first time how insects use magnetic cues to navigate, isolating which of the two current (contentious) hypotheses for magnetic sensation apply. The most likely of these involves the action of - photoreceptor-based cryptochrome (Cry) molecules in the eyes. Having cloned genes for 4 visual opsins and 2 Cry in Bogong moths, I will use in situ hybridisation to localise putative magnetoreceptors in the eyes, targeting them with intracellular - electrophysiology and magnetic stimulation in an attempt to describe the physiology of these elusive sensors for the first time. The project is ground breaking since it will elucidate how a migratory insect, despite its small eyes and brain, detects - and uses the Earth’s magnetic field for navigation. The discovery of the enigmatic magnetoreceptor would be a sensation, opening the floodgates for international research on this little understood sense. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Sweden - - - MagneticMoth - - - ERC-2016-ADG - - - 741298 - - - - - FACULDADE DE ARQUITETURA DA UNIVERSIDADE DE LISBOA (UL) - - - EUR 160 635,60 - - - 3D SMART MODELS FOR HERITAGE CONSERVATION An Open Science project for documentation, management and representation of Cultural Heritage - - - EUR 160 635,60 - - - Portugal - - - Higher or Secondary Education Establishments - - In today’s society, three-dimensional models of the tangible heritage present the greatest potential for heritage conservation efforts, due to advances in display devices, capabilities, and infrastructure costs, etc. However, - in reality, these models do not always provide the necessary accuracy; they require an arduous process of managing and transforming; and they are not set up for reuse and long-term archiving. Without such capabilities we are left with inadequate - knowledge that leads to higher expenses and time costs during documentation of fieldwork, disconnected bodies of geospatial data, and over-dimensioned and disorganised information. These problems further limit the scope and efficiency of the use of - digital heritage resources for professionals, and restrict the accessibility of these resources to a wider audience without technical literacy, therefore constraining conservation and reuse practices throughout society. - - - 2019-06-04, ongoing project - - - 2017-06-05 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Portugal - - - 3D-SMoHC - - - H2020-MSCA-IF-2016 - - - 747046 - - - - - UNIVERSITETET I BERGEN - UNIVERSITETET I BERGEN - - - EUR 2 413 371 - - - Perception of voices that do not exist: Tracking the temporal signatures of auditory hallucinations - - - EUR 2 413 371 - - - Norway - Norway - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - "One of the most perplexing phenomena of the human mind is the conviction of perceiving a "voice" in the absence of an external auditory source. This is called an auditory hallucination (AH), and is the most characteristic - symptom of the most severe mental disorder, schizophrenia. Understanding the phenomenology, cognitive, and neurobiological underpinnings of AHs will not only provide new insights for explaining schizophrenia, but will also provide new insights into - the "complexities of the mind". In my previous research, I have uncovered the neurocognitive markers of the initiation of an AH, focusing on what causes the onset of a hallucinatory episode. The current proposal further narrows the focus, asking a - single question; why do AHs spontaneously come-and-go over time, or stated otherwise, why are they not permanently present once initiated? If we believe that the onset of an episode has neurocognitive markers, which all evidence supports, then we - must also acknowledge that the offset must have corresponding markers. This question has to my knowledge never been addressed, although it is vital for the understanding of the underlying mechanisms, and for new treatment strategies. I will track the - fluctuations of AH episodes in real-time with iPhone app technology, going beyond interview questionnaires. I will track how cognition modulates the onset and offset with an experimental dichotic listening paradigm, going beyond standard tests. I - will track what happens in the brain the few seconds before the onset and, in particular the offset of an episode, using component-based fMRI analysis, going beyond "blobology". I will track with MR spectroscopy the interaction of excitatory and - inhibitory transmitters that are hypothesized to mediate episode onsets and offsets, respectively, going beyond systems imaging. Thus, I will track AH episodes from the clinical to the receptor level, working vertically through a “levels of - explanation” model, from higher to lower levels" - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Norway - - - ONOFF - - - ERC-2015-AdG - - - 693124 - - - - - UNIVERSITY OF BRIGHTON - - - EUR 195 454,80 - - - The Impact of Intangible Cultural Heritage (ICH) in formal, non-formal and informal education and its contribution to the Key Competences for Lifelong Learning in the EU Reference Framework - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Europe’s Intangible Cultural Heritage – the skills, music, dance, drama, gastronomy, festivals, crafts, etc which have been passed from one generation to the next – is a hugely important economic and social resource. Yet this - aspect of cultural heritage is poorly researched. ‘ICH-Bildung’ proposes to redress that balance and study the Impact of Intangible Cultural Heritage (ICH) in formal, non-formal and informal education and its contribution to the Key Competences for - Lifelong Learning in the European Reference Framework. - - 2017-04-30, closed project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - United Kingdom - - - ICH-Bildung - - - H2020-MSCA-IF-2014 - - - 661385 - - - - - UNIVERSIDAD DE BURGOS - - - EUR 170 121,60 - - - Molecular to Continuum Investigation of Anisotropic Thermal Transport in Polymers - - - EUR 170 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - In 2014, EU PLASTICS INDUSTRY accounted for 1.4MM jobs and contributed to high living standards of the EU citizens by enabling new and more affordable technologies. Most of the PROCESSING of POLYMERIC MATERIALS occurs under - NON-ISOTHERMAL flow conditions. As a result, the COST/ENERGY REQUIRED to manufacture, recycle and dispose polymers is STRONGLY AFFECTED by the thermo-physical properties linkage to state variables such as temperature and stress. Experiments show that - flowing polymers exhibit ANISOTROPIC THERMAL CONDUCTIVITY (ATC) (i.e. direction dependent). This phenomenon has been previously NEGLECTED in both the simulation of INDUSTRIALLY relevant flows and the development of a molecularly-based THEORY for - thermal transport in polymers. - - - 2019-10-15, ongoing project - - - 2017-10-16 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - MCIATTP - - - H2020-MSCA-IF-2016 - - - 750985 - - - - - FUNDACION IMDEA MATERIALES - - - EUR 85 060,80 - - - Characterization and Modelling of dislocation-INterface Interactions in MetAllic Laminates at multiple scales - - - EUR 85 060,80 - - - Spain - - - Research Organisations - - The global market will increase from $11 billion in 2012 to $22.5 billion in 2018 for micro electro mechanical systems (MEMS), and from $1.9 billion in 2012 to $6.6 billion in 2018 for BioMEMS. Recently, metallic nanolaminates - have attracted application as mechanical parts in MEMS and BioMEMS manufacturing. This is due to their superior properties, i.e. large flow strength, high indentation hardness, excellent ductility, good radiation damage resistance, qualified - electrical/magnetic response, and promising fatigue/failure resistance. In order to address the performance of metallic nanolaminates and to reduce materials’ failure and cost under different service conditions, better analysis/predictive tools are - required for dislocation-interface interactions. The improved analysis/predictive tools will allow designing more advanced nanolaminate materials. However, to develop such analysis/predictive tools, it entails (a) in-depth understanding of the - physical mechanisms behind dislocation-interface interactions, (b) accurate in-situ mechanical testing data at different length scales from micro- to nanometers, and (c) efficient numerical modelling to predict dislocation-interface interactions. - Through this Marie Skłodowska-Curie action, we will contribute significantly towards improving these analysis/predictive tools from two aspects, including (i) providing the scientific knowledge behind dislocation-interface interactions, and (ii) - establishing improved numerical models to predict dislocation-interface failure during service. Meanwhile, the new advanced nanolaminate materials with enhanced properties will also be proposed based on the generated knowledge. In addition, the - researcher and the host organization will benefit from the two-way transfer of knowledge between them. - - 2019-04-30, Grant Agreement signed - - - 2018-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - MINIMAL - - - H2020-MSCA-IF-2016 - - - 749192 - - - - - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - - - EUR 183 454,80 - - - Evaluation of three-dimensional velocity field, mixing field, and flame-front in a model gas turbinecombustor - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - As noted by European turbine network, gas turbine is and will remain dominant mode of energy conversion. An advanced experimental study of a model gas turbine combustor is proposed. The lasers play indispensable role in the - experimental combustion research due to the associated non-intrusive nature. The laser diagnostics have evolved from a point measurement to planar measurement (2D) over the years. The objective of the present work is to develop novel laser - diagnostics to deduce instantaneous 3D fields of the flow, air/fuel mixing, and flame-front topology in a 'volume'. The proposed technique will be applied to a model gas turbine combustor operating with and without combustion instability. A scanning - stereoscopic Particle Image Velocimetry (flow field) and Laser Induced Fluorescence of CH2O radical (flame-front) and of fuel concentration will be assembled correlated with pressure traces. A 4 head Nd:YAG laser cluster will generate 4 parallel - laser sheets separated in space and images will be recorded by high speed cameras. The novel use of laser cluster ensures high pulse energy and temporal resolution. Image processing will be developed to reconstruct the 3D fields from the planar - slices. The approach will be validated in a Bunsen burner before applying it to swirl stabilized flames that mimic a typical gas turbine combustor. The technology readiness level (TRL) of the research will reach between TRL 3 to 4. The proposed - research will diversify the skill set of the researcher and associated complementary training will ensure that the fellow becomes an established academic researcher. The impact of this work is the generation of a unique 3D flame database, which is of - great importance for the understanding of turbulent flame-flow interaction and the evaluation of advanced numerical combustion models. Thus, the proposed research will enhance European competitiveness in gas turbine design and can have an impact on - automotive engine development. - - 2020-01-01, ongoing project - - - 2018-01-02 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - 3DFlameGT - - - H2020-MSCA-IF-2016 - - - 747576 - - - - - UNIVERSITA COMMERCIALE LUIGI BOCCONI - UNIVERSITA COMMERCIALE LUIGI BOCCONI - - - EUR 1 375 869 - - - Explaining Politicians' and Voters' Behavior - - - EUR 1 375 869 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Theoretical models and empirical studies in political economy aim at explaining both the beliefs and the choices of voters and politicians, so as to assess their impact on economic policy. In particular, a recent literature - has recognized the crucial relevance of the identity of politicians in taking policy decisions and ultimately in shaping the fate of their country (Besley 2005; Jones and Olken 2005). In this project, we will address two neglected elements in the - existing literature: the role of political parties as organizational structures that shape political careers (i.e., who gets on top in democracies); and the nature of social preferences, personality traits, and cognitive biases in understanding the - beliefs and the choices of both politicians and voters. - - 2021-07-31, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Italy - - - POLITICALMIND - - - ERC-2014-CoG - - - 648833 - - - - - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - - - EUR 195 454,80 - - - DATASOUND: Understanding data with sound - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - More and more, organizations are generating huge amounts of data, which need to be stored and processed in order to gain useful insights and achieve competitive advantage. While the storage and analysis are nowadays mostly - carried out by computers, the interpretation of data is still performed by humans through visual means. - - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - DATASOUND - - - H2020-MSCA-IF-2016 - - - 743623 - - - - - UNIVERSITE DE BORDEAUX - - - EUR 173 076 - - - Personal Ornaments in the Palaeolithic of Europe - - - EUR 173 076 - - - France - - - Higher or Secondary Education Establishments - - The project PeOPLE (Personal Ornaments in the PalaeoLithic of Europe) seeks a new perspective on the archaeological framework for Eastern Europe during the earlier part of the Upper Palaeolithic (UP) by study of the beads and - other personal ornaments known from sites of this period. The study period covers ca. 45,000-25,000 years ago – the first twenty thousand years of modern human occupation of ice age Europe. - - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - PeOPLE - - - H2020-MSCA-IF-2016 - - - 747400 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 173 076 - - - Investigating the role of bacteria-produced siderophores in satisfying diatom Fe requirements. - - - EUR 173 076 - - - France - - - Research Organisations - - The greatest impact of climate change will be exerted on ocean biomes. In order to mitigate for its effects it is paramount to understand the dynamics of phytoplankton communities within, which are responsible for marine - carbon fixation (50% of the of the primary production on Earth). Our current understanding of phytoplankton dynamics is limited – particularly when linking a molecular level understanding of metabolic processes with ecology. In the proposed work I - will investigate the hypothesis that diatoms, which are ubiquitous phytoplankton species across all marine habitats interact with bacteria to acquire bioavailable iron from siderophores produced by the latter. My investigations will address this aim - across all scales of biological organization. I will capitalize on preliminary investigations at the host laboratory that have begun to unravel the molecular pathways associated in siderophore acquisition in diatom species. My work will be novel in - terms of characterizing the molecular mechanism by which siderophores are transported into and distributed to where required within diatom cells. Further, I will explore the hypothesis that siderophore acquisition is a result of mutualism between - bacteria and diatoms. The results will bear important eco-evolutionary consequences to our understanding of microbial communities. Finally, on a global scale, I will quantify the relevance of my findings by mining of metatranscriptomic data collected - in global transects of the ocean (specifically during the Tara Oceans expedition). Through this fellowship I will develop a range of new technical skills including novel molecular techniques and bioinformatics, as well as transferable competencies - (e.g. using French at work). The fellowship will provide me with an opportunity to return to Europe (from the USA), expanding my academic network of collaborators and putting me in a prime position for applying for faculty positions as a next step in - my academic career. - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - IRONCOMM - - - H2020-MSCA-IF-2016 - - - 748581 - - - - - THE QUEEN'S UNIVERSITY OF BELFAST - - - EUR 183 454,80 - - - A ductile, high energy absorptive and rapid post-tensioning system for extending life of concrete structures - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Extending the service life of reinforced concrete structures not only represents an economical advantage to owners, but also significantly contributes to the sustainability of the built environment, through the saving of - natural resources and reduction of green gas emissions. In view of the shortcomings of the most commonly used strengthening techniques, such as FRP systems, the state of the structural retrofitting art demands a robust retrofitting solution feasible - of rapid installation and easy post-tensioning applications along with a high energy dissipation capacity (e.g. independently of the quality and thickness of concrete cover, no need of mechanical devices for the post-tensioning applications and an - adhesive free connection system) for specific cases such an strengthening against earthquake, impact and blast due to either accidents or terrorist attacks. This product-oriented proposal aims to develop an innovative element, herein after designated - SMArtPlate to meet these requirements. Such a thin prefabricated plate will be precisely tailored to utilize the synergistic advantages of two advanced materials for the retrofitting of RC structures: ductile fiber reinforced geopolymer mortar and - shape memory alloys (SMA). Following an interdisciplinary approach, experimental and numerical investigations will be conducted to develop and assess strengthening performance of the SMArtPlate. - - 2019-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SMArtPlate - - - H2020-MSCA-IF-2016 - - - 753903 - - - - - BUREAU DE RECHERCHES GEOLOGIQUES ET MINIERES - - - EUR 173 076 - - - Institutions for Resilient Groundwater Dependent Rural Economies - - - EUR 173 076 - - - France - - - Research Organisations - - Groundwater is a strategic resource for modern economies worldwide; yet it is over-exploited at an alarming rate. New forms of governance are sought, in particular in rural areas with intensive agricultural irrigation where - authorities lack the means to regulate large numbers of dispersed users. During the Fellowship, I will develop new understanding of strategies and institutional arrangements for increasing the resilience of groundwater dependent rural economies, and - develop and test a methodology that support local actors to design collective solutions. Overall, the Fellowship aims to: (1) carry out a global assessment of strategies and institutions currently used worldwide; (2) develop a participatory foresight - methodology to support the design of innovative strategies and institutional arrangements in two case studies; and (3) promote academic exchange and disseminate research. The Fellowship will enable me to strengthen my empirical and theoretical - knowledge of the design of institutions for common-pool resource management and natural resource management, and position me as a leading scholar in the competitive research community on environmental and institutional economics. A carefully crafted - series of scientific exchanges and collaborations will expand my outreach to a global level, and open opportunities for new research collaborations. The French Geological Survey (BRGM), France, is the ideal host organisation to carry out this - research because of its established expertise on groundwater management with an emphasis on inter-disciplinary research of high societal relevance, and its extensive global networks. I will contribute to BRGM’s current research agenda and strengthen - its collaborations in and outside Europe. My research will contribute to Europe’s knowledge base economy by providing new insights to safeguard society against water-related vulnerabilities. - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - RURECO - - - H2020-MSCA-IF-2016 - - - 750553 - - - - - CONSORCIO PARA LA CONSTRUCCION EQUIPAMIENTO Y EXPLOTACION DEL LABORATORIO DE LUZ SINCROTRON - - - EUR 158 121,60 - - - Getting new insights into the radio-sensitization effects of nanoparticles in photon and charged particle therapy - - - EUR 158 121,60 - - - Spain - - - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - The use of high-atomic-number nanoparticles (NP) as tumour radio-sensitizers has been recently proposed as a breakthrough in radiotherapy (RT). Numerous biological studies have shown the enhanced effectiveness in tumor cell - killing when NP were associated to photon RT and, more recently, to charged particle therapy. However, the mechanisms of action are not clear yet. In addition to the damage due to a possible local dose enhancement (physical effects), the interaction - of NP with essential biological macromolecules could lead to changes in the cells (biochemical effects) leading to an amplified effect of the radiation. Within this framework, the main goal of the NANOCANCER project is to get deeper insights into the - mechanisms underlying the amplification of radiation effects of NP. For this purpose, I will use a multidisciplinary strategy to evaluate both the biochemical and physical effects involved in these innovative nano-RT approaches. Vibrational - spectroscopy (Fourier transform infrared, FTIR, microspectroscopy) will be employed for the first time to investigate the biochemical features in glioma cells combining two high-Z standard nanoparticles (Au and Gd) and charged particle beams. - Physical effects will be also assessed by performing complementary Monte Carlo simulation of radiation transport, which will allow a realistic modelling of early biological damages induced by the radiation at the nanometre scale. This - interdisciplinary proposal will be essential to better characterize the radio-sensitization effects of NP in glioma cells and, in addition, will bring light to the present charged particle therapy radiobiology, which seems to lead to substantially - different tumour responses with respect to conventional RT at the cellular and molecular level. The knowledge of these biochemical features will help researchers to develop RT by taking full advantage of the underlying biology an enhance the - therapeutic index of RT for diseases with poor prognosis. - - 2019-10-29, ongoing project - - - 2017-10-30 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-SE - Society and Enterprise panel - - - Spain - - - NANOCANCER - - - H2020-MSCA-IF-2016 - - - 748889 - - - - - QUEEN MARY UNIVERSITY OF LONDON - - - EUR 183 792,60 - - - Mechanobiology of METAstatic and DORMant cancer cells in bone marrow lesions - - - EUR 183 792,60 - - - United Kingdom - - - Higher or Secondary Education Establishments - - While cancer survival rates have improved significantly in recent years, survival decreases dramatically after tumour metastasis. One of the most common sites for metastatic tumours to develop is bone. Intriguingly, evidence - suggests that once they have invaded the bone marrow, individual metastatic cancer cells can persist for years in a quiescent or “dormant” state, and are resistant to both radiation and chemotherapy treatment. These dormant cells can reside for - months or years while the cancer is in remission, and then “reactivate” without warning to form new, usually fatal, skeletal lesions. Tumour cells achieve this by “hijacking” the normal bone remodelling cycle, a homeostatic balance between bone - formation and resorption, to form a metastatic niche within the marrow. However, the signalling mechanisms that cause metastasis and dormancy, particularly in such a mechanically active environment, are poorly understood. Therefore, the goal of this - project is to investigate the chemical and physical interactions between bone and cancer cells, both during dormancy and mechanical stimulation, to provide new insight into bone metastatic lesions and explore novel therapeutic targets to prevent - cancer metastasis. This will be achieved by culturing specific bone and cancer cell types together for the first time to observe changes in their signalling and behaviour. Dormancy will also be induced, to observe its effect on changes in signalling. - Mechanical stimulation will be applied to investigate whether the complex mechanical environment of the bone marrow plays a role in cancer metastasis. Finally, a specific cellular mechanosensor, the primary cilium, which has been implicated in the - development of cancer and is known to be involved in bone formation, will be investigated. This will shed new light on its chemosensing and mechanobiological roles in cancer metastasis, as well as explore its potential as a novel target for cancer - treatment and prevention. - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - META-DORM - - - H2020-MSCA-IF-2016 - - - 748305 - - - - - ANGLIA RUSKIN UNIVERSITY HIGHER EDUCATION CORPORATION - - - EUR 195 454,80 - - - ENvironmental COnditions in GLAucoma Patients - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Glaucoma is a common eye pathology that can lead to blindness. As it is a progressive disease, longer-term treatment is required for its control, based mainly on the regular use of topical eye drops. Adherence to the treatment - is the degree to which a patient’s behaviour in taking medication corresponds with agreed recommendations from their doctor. Various risk factors for non-adherence to the glaucoma treatment have been identified, but the role played by an individual’s - ocular surface characteristics and the influence of different environmental conditions are not well understood. The objectives of ENCOGLAP (ENvironmental COnditions in GLAucoma Patients) are to determine which ocular surface characteristics and - environmental conditions will influence non-adherence to treatment. The influence of preservatives in eye drops will also be investigated. The overarching aim is to provide a guide of “risk factors of non-adherence” that could be used in the clinical - practice. - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - United Kingdom - - - ENCOGLAP - - - H2020-MSCA-IF-2016 - - - 747441 - - - - - IPATIMUP - INSTITUTO DE PATOLOGIA E IMUNOLOGIA MOLECULAR DA UNIVERSIDADE DO PORTO PCUP - - - EUR 148 635,60 - - - 3D glyco-engineered models to address the role of glycosylation in gastric cancer clinical management - - - EUR 148 635,60 - - - Portugal - - - Research Organisations - - Gastric cancer is an important health problem, being the fifth most common cancer and the third leading cause of cancer death. Its late diagnosis accompanied with a bad prognosis keeps this malignancy among the most deadly. - - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Portugal - - - GlycoModels - - - H2020-MSCA-IF-2016 - - - 748880 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 150 000 - - - Light-engaged Accommodating IOL - - - EUR 150 000 - - - Spain - Spain - - - Research Organisations - Research Organisations - - Presbyopia, the age-related loss of the ability of the eye to focus near and far objects, affects 1.2 billion people in the world. While there are a number of corrections for presbyopia available (near and progressive - spectacles, monovision or multifocal lenses) none of these restore the dynamic focusing capability of the young crystalline lens. - - - 2019-06-30, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Spain - - - Light AIOL - - - ERC-2016-PoC - - - 754630 - - - - - UNIVERSITE DE GENEVE - - - EUR 187 419,60 - - - Molecular mechanisms of endosome departure from the spindle in asymmetric cell division - - - EUR 187 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - During mitosis, cells can undergo asymmetric cell division, where daughter cells are endowed with different fates. Asymmetric division enables developing organisms to generate their particular diversity of cell types through a - balanced combination of self-renewal and differentiation. Better understanding the mechanisms of asymmetric cell division will shed light on how cell renewal, differentiation and proliferation are controlled. In the longer term, this knowledge might - enable regenerating defective cells in ageing and disease, generating cells of a particular identity for therapeutic purposes and tackling cell proliferation in cancer. - - 2019-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - ENDODEP - - - H2020-MSCA-IF-2016 - - - 750335 - - - - - UNIVERSITE DE TOULOUSE II - LE MIRAIL - UNIVERSITE DE TOULOUSE II - LE MIRAIL - - - EUR 2 432 062 - - - Mapping Ancient PolytheismsCult Epithets as an Interface between Religious Systems and Human Agency - - - EUR 2 432 062 - - - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Writing the history of ancient religions usually starts with the gods, considered as personifications linked by kinship or affinity. Yet this oversimplified approach overlooks the fact that gods are multifaceted powers, not - individuals. MAP proposes to exploit the epithets attributed to the gods as the most efficient indicator of their multiple powers and modes of action, as well as their connection to places where humans interact with them. Epithets identify the god(s) - invoked and thus enhance the effectiveness of ritual communication. With the great number of combinations produced by epithets, their entire repertoire results in a highly complex system of divine networks. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - France - - - MAP - - - ERC-2016-ADG - - - 741182 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 255 697,50 - - - New Directions in Derived Algebraic Geometry - - - EUR 1 255 697,50 - - - France - France - - - Research Organisations - Research Organisations - - New Directions in Derived Algebraic Geometry: In this proposal we propose to give a new impulsion on derived algebraic geometry by exploring new domains of applicability as well as developing new ideas and fundamental results. - For this, we propose to focus on the, still very much unexplored, interactions of derived algebraic geometry with an extremely rich domain: singularity theory (to be understood in a broad sense, possibly in positive and mixed characteristics, but - also singularities of meromorphic flat connections and of constructible sheaves). We plan to use the fruitful interactions between these two subjects in a two-fold manner: on the one hand derived techniques will be used in order to prove long - standing open problems, and on the other hand we propose new developments in derived algebraic itself and thus open new research directions.The proposal has three major parts, interacting with each other in a coherent manner. In a first part we - explore some direct applications of derived techniques to the study of singularities of degenerating families of proper schemes with the objective to prove a long standing major conjecture in the subject: the Bloch’s conductor formula. This is - achieved by the introduction of a new trend of ideas in non-commutative geometry and more precisely by the introduction of a trace formula in the non-commutative setting. The second part is devoted to the exploration of trace and index formula for - sheaves in two different, but very similar, setting: l-adic constructible sheaves and quasi-coherent sheaves with flat connections along a given algebraic foliations. In a third part we propose to make progress towards an unexplored domain: moduli - spaces of flat, possibly irregular, connections on higher dimensional varieties and their relations with Poisson and symplectic geometry. The objective here is a far reaching generalization of fundamental results on moduli spaces of flat connections - on open curves and their symplectic aspects. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - France - - - NEDAG - - - ERC-2016-ADG - - - 741501 - - - - - KOC UNIVERSITY - KOC UNIVERSITY - - - EUR 150 000 - - - Augmented Reality Wearable Platform and Screen: Proof of Concept and Commercialization - - - EUR 150 000 - - - Turkey - Turkey - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Wear3D display technology project is an ERC-Advanced project and offers novel optical solutions for wearable (or head-mounted) displays to achieve very wide field-of-view and natural-looking 3D. The Wear3D technology has a lot - of potential as the global consumer market for AR and VR are expected to reach more than US$30 billion and US$120 billion by 2022, respectively. Hardware devices will be more than 30% of the total market. - - 2018-10-31, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Turkey - - - MIRAGE - - - ERC-2016-PoC - - - 755154 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 149 811 - - - Implementing Special Nanomaterials in Ultra-performance Mobile Radomes - - - EUR 149 811,25 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - OxfordNano aims to enhance the EU manufacturing capability in aerospace composite structures using special nanomaterials (NMs) technology derived from ERC research. The target application for this capability is - ultra-performance radomes for airborne sensors systems and a growing opportunity to deliver digital services to users on the move e.g. passengers in civil aircraft and trains. - - 2019-01-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - OxfordNano - - - ERC-2016-PoC - - - 754748 - - - - - UNIVERSITY OF KENT - UNIVERSITY OF KENT - - - EUR 149 300 - - - Adapter for a commercial grade camera or a smart phone to perform depth resolved imaging - - - EUR 149 300 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The proposal refers to a patented adapter that can transform a commercial grade digital camera or the camera in a smart phone into a depth resolved imaging instrument. Several adapters will be assembled, making use of optical - coherence tomography (OCT) technology protected by some other of PI’s patents. The activity takes advantage of recent progress in commercial grade cameras in terms of their modes of operation as well as in terms of parameters of their devices, such - as sensitivity and speed of their photodetector arrays. - - 2018-11-30, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - AdaSmartRes - - - ERC-2016-PoC - - - 754695 - - - - - UNIVERSITE PARIS-SUD - UNIVERSITE PARIS-SUD - - - EUR 1 263 607 - - - Brownian geometry: at the interface between probability theory, combinatorics and mathematical physics. - - - EUR 1 263 607 - - - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The main purpose of this proposal is to explore the canonical models of planar random geometry that have been introduced in the recent years. We call this theory Brownian geometry because one of the central objects, the - Brownian map, arises as the universal scaling limit of many discrete models of large random graphs embedded in the plane, in a way very similar to Brownian motion, which is the continuous limit of many different classes of random paths. The preceding - scaling limit holds for the Gromov-Hausdorff distance on compact metric spaces. Furthermore, recent developments show that, in addition to its metric structure, the Brownian map can be equipped with a conformal structure. - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - France - - - GeoBrown - - - ERC-2016-ADG - - - 740943 - - - - - TECHNISCHE UNIVERSITEIT DELFT - TECHNISCHE UNIVERSITEIT DELFT - - - EUR 149 998 - - - Adaptive Imaging Microscopy - - - EUR 149 998 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The project has a goal of starting up a small business producing highly special customizable microscope systems for biomedical research. Microscopic imaging is one of the major drivers of the progress in biomedical and life - sciences. The development of novel concepts, addressing the challenges of advanced optical microscopy, represents the front line of scientific research. Modern microscopes are not purely optical devices anymore. They have developed into complex - integrated systems, combining optics, mechanics, electronics, feedback control systems, and image processing Many novel concepts of modern microscopy, while very interesting for research, still have to prove the commercial profitability. Such - developments can be effectively addressed by start-up companies with a goal of either custom development, production and service of these advanced systems, or development and selling the IP to a larger player. - - - 2018-10-31, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Netherlands - - - AIM - - - ERC-2016-PoC - - - 737564 - - - - - UNIVERSITEIT UTRECHT - UNIVERSITEIT UTRECHT - - - EUR 2 000 000 - - - Can Limitarianism Be Justified? A Philosophical Analysis of Limits on the Distribution of Economic and Ecological Resources - - - EUR 2 000 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In contemporary normative political philosophy, questions of distributive justice have focused on meeting minimal needs of persons, prioritizing the worst-off and reducing inequalities. In philosophy, these views are called - ‘sufficientarianism’, ‘prioritarianism’ and ‘egalitarianism’. The proposed project —Fair Limits— shifts the focus to ‘limitarianism’, the view that there should be upper limits on the distribution of valuable goods, and will investigate the - plausibility of limitarianism in the area of economic and ecological resources. We will analyse whether such a view can be justified, that is, supported by robust philosophical argumentation, and what limitarian institutions could look like. - - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - FAIR LIMITS - - - ERC-2016-COG - - - 726153 - - - - - NATURAL ENVIRONMENT RESEARCH COUNCIL - NATURAL ENVIRONMENT RESEARCH COUNCIL - - - EUR 1 999 110 - - - Gauging Ocean organic Carbon fluxes using Autonomous Robotic Technologies - - - EUR 1 999 110 - - - United Kingdom - United Kingdom - - - Research Organisations - Research Organisations - - Climate change driven by CO2 emissions from human activities is a significant challenge facing mankind. An important component of Earth’s carbon (C) cycle is the ocean’s biological C pump; without it atmospheric CO2 would be - ~50% higher than it is now. The pump consists of sinking organic matter which is remineralised back into CO2 in the deep ocean. The depth at which remineralisation occurs is the main factor affecting the amount of organic C stored in the ocean. - Currently we do not understand how or why remineralisation depth varies in time, which limits our ability to make robust predictions of how the future C cycle, and hence our climate, will change into the future. This is mainly due to the challenges - of measuring remineralisation depth using conventional methods– a barrier which autonomous underwater vehicles are poised to overcome by providing high frequency data over long periods. This technological innovation will revolutionise our - understanding of this important planetary C flux. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - GOCART - - - ERC-2016-COG - - - 724416 - - - - - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - - - EUR 1 999 025 - - - Establishment and maintenance of gene expression by heterochromatin factors - - - EUR 1 999 025 - - - France - France - - - Research Organisations - Research Organisations - - Metastable epialleles are alleles that are variably expressed in genetically identical individuals. These epialleles are established during early development by epigenetic modifications in a process influenced by stress and - the environment. The epiallele’s state can subsequently be maintained throughout development and adult life. Studying the mechanisms underlying establishment and maintenance of chromatin states is critical to understanding how the environment can - shape the epigenome and how it can impact on diseases and aging. Most mouse metastable epialleles result from a nearby insertion of an endogenous retrovirus, which induces position effect variegation. In mouse embryonic stem cells, these elements are - silenced by the histone methyl-transferase SETDB1 which imparts heterochromatin features by tri-methylating histone H3 on lysine 9. In the same cells, telomeric H3K9me3 is also installed by SETDB1 but surprisingly, we found that H3K9me3 correlates - with enhanced transcriptional activity at telomeres. I hypothesize here that metastable chromatin states are controlled by H3K9me3 and associated factors, which are targeted to defined positions that can either instruct silencing, or support active - expression. To understand how metastable chromatin states are regulated, we will first use a locus-specific chromatin proteomics approach to identify H3K9me3-dependent factors in the contexts of transcription or repression. Next, both pathways will - be reconstituted by tethering those factors at specific positions on model genes, and maintenance of these states will be analyzed. Finally, to obtain a comprehensive picture of the metastable states establishment and maintenance, we will map - heterochromatin factors genome-wide, in response to distinct stimuli in mESCs. This proposal will deepen our understanding of the mechanisms by which mammals use gene regulation to adapt to environmental conditions. - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - France - - - METACHROM - - - ERC-2016-COG - - - 724835 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 2 225 713 - - - constRaining the EffeCts of Aerosols on Precipitation - - - EUR 2 225 713 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Precipitation is of fundamental importance so it is vital to understand its response to anthropogenic perturbations. Aerosols have been proposed to significantly affect precipitation [e.g. Ramanathan et al., 2001]. However, - despite major research efforts evidence for a systematic aerosol effect on precipitation remains “ambiguous” [IPCC AR5, Stocker et al., 2013]. - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - RECAP - - - ERC-2016-COG - - - 724602 - - - - - UNIVERSIDADE DO MINHO - UNIVERSIDADE DO MINHO - - - EUR 1 998 938,92 - - - Cells-self Extracellular Matrices-based Bioinks to create accurate 3D diseased skin tissue models - - - EUR 1 998 938,92 - - - Portugal - Portugal - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - It has been recognized that growing cells within 3D structures reduces the gap between 2D in vitro cell cultures and native tissue physiology. This has been paving the way for the development of reliable 3D in vitro cell-based - platforms with major impact in the reduction/elimination of animal experimentation, diseases modelling and drug development. So far, the many strategies that have been followed to bioengineer in vitro 3D human tissue models mostly rely on the random - culture of cells within a 3D structure without reflecting the compositional and structural complexity of the native tissues. Recently proposed bioprinting technologies that allow accurate and high speed deposition of various cells and matrices at - high resolution, have therefore great potential in the development of physiologically reliable 3D in vitro tissue models by recreating the different microenvironments/microfunctionalities found in each tissue. Nonetheless, among the components - required for bioprinting, bioinks in particular have demanding requirements and much has still to be done regarding their intrinsic formulation to lead cell behaviour and support specific functionalities. - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Portugal - - - ECM_INK - - - ERC-2016-COG - - - 726061 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 947 208 - - - Boosting tryptophan fluorescence with optical nanoantennas to watch label-free protein dynamics with single molecule resolution at high concentration - - - EUR 1 947 208,13 - - - France - France - - - Research Organisations - Research Organisations - - Proteins execute a broad range of functions that are central to life. Understanding these functions ultimately requires experiments at the single protein level to reveal dynamics and heterogeneities hidden in ensemble-averaged - measurements. Currently, the preferred method to study single protein machineries is based on fluorescence techniques. However, fluorescence experiments suffer from major challenges: the need for external fluorescent labeling, weak signals and low - non-physiological concentrations in the nanomolar range. These challenges severely limit the applicability and biological relevance of single molecule fluorescence on proteins. The TryptoBoost project aims to overcome all the previous challenges, and - efficiently monitor single label-free proteins using their intrinsic tryptophan fluorescence enhanced by optical nanoantennas in the ultraviolet. Using the natural amino acid fluorescence rules out all drawbacks due to external labeling, while the - optical nanoantennas enable single protein analysis at the physiologically relevant micromolar concentrations thanks to the localization and enhancement of light-matter interactions at the nanoscale. To demonstrate the power of this new technology, - our interdisciplinary team will probe the important biological problems of amyloid aggregation and tumor suppressor p53 protein folding dynamics at high concentrations. The TryptoBoost approach is directly applicable to any protein containing - aromatic amino acids. This condition is met by more than 90% of human proteins, so the project breakthroughs will benefit a broad range of biophysical, chemical, and medical applications. For instance, it will improve the development of therapeutic - drugs, increase the detection sensitivity and read-out speed in analytical biosensing on chip, and provide new nanostructures to enhance ultraviolet photocatalysis. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - France - - - TryptoBoost - - - ERC-2016-COG - - - 723241 - - - - - WEIZMANN INSTITUTE OF SCIENCE - WEIZMANN INSTITUTE OF SCIENCE - - - EUR 2 461 111 - - - Celestial fireworks: revealing the physics of the time-variable sky - - - EUR 2 461 111 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Experimental time-domain astrophysics is on the verge of a new era as technological, computational, and operational progress combine to revolutionise the manner in which we study the time-variable sky. This proposal - consolidates previous breakthrough work on wide-field surveys into a coherent program to advance our study of the variable sky on ever decreasing time-scales: from days, through hours, to minutes. We will watch how stars explode in real time in order - to study the complex physics of stellar death, build new tools to handle and analyse the uniquely new data sets we are collecting, and shed light on some of the most fundamental questions in modern astrophysics: from the origin of the elements, via - the explosions mechanism of supernova explosions, to the feedback processes that drive star formation and galaxy evolution. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Israel - - - Fireworks - - - ERC-2016-COG - - - 725161 - - - - - FUNDACIO CENTRE DE REGULACIO GENOMICA - FUNDACIO CENTRE DE REGULACIO GENOMICA - - - EUR 1 986 178 - - - Reticulate evolution: patterns and impacts of non-vertical inheritance in eukaryotic genomes. - - - EUR 1 986 178 - - - Spain - Spain - - - Research Organisations - Research Organisations - - The traditional view is that species and their genomes evolve only by vertical descent, leading to evolutionary histories that can be represented by bifurcating lineages. However, modern evolutionary thinking recognizes - processes of reticulate evolution, such as horizontal gene transfer or hybridization, which involve total or partial merging of genetic material from two diverged species. Today it is widely recognized that such events are rampant in prokaryotes, but - a relevant role in eukaryotes has only recently been acknowledged. Unprecedented genomic and phylogenetic information, and recent work from others and us have shown that reticulate evolution in eukaryotes is more common and have more complex outcomes - than previously thought. However, we still have a very limited understanding of what are the impacts at the genomic and evolutionary levels. To address this, I propose to combine innovative computational and experimental approaches. The first goal is - to infer patterns of reticulate evolution across the eukaryotic tree, and relate this to current biological knowledge. The second goal is to trace the genomic aftermath of inter-species hybridization at the i) long-term, by analysing available - genomes in selected eukaryotic taxa, ii) mid-term, by sequencing lineages of natural fungal hybrids, and iii) short-term, by using re-sequencing and experimental evolution in yeast. A particular focus is placed on elucidating the role of - hybridization in the origin of whole genome duplications, and in facilitating the spread of horizontally transferred genes. Finally results from this and other projects will be integrated into emerging theoretical frameworks. Outcomes of this project - will profoundly improve our understanding of reticular processes as drivers of eukaryotic genome evolution, and will impact other key aspects of evolutionary theory, ranging from the concept of orthology to the eukaryotic tree of life. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Spain - - - RETVOLUTION - - - ERC-2016-COG - - - 724173 - - - - - HELMHOLTZ-ZENTRUM FUER INFEKTIONSFORSCHUNG GMBH - HELMHOLTZ-ZENTRUM FUER INFEKTIONSFORSCHUNG GMBH - - - EUR 1 998 750 - - - Clearance Of Microbial Biofilms by Advancing diagnostics and Therapy - - - EUR 1 998 750 - - - Germany - Germany - - - Research Organisations - Research Organisations - - Every year chronic infections in patients due to biofilm formation of pathogenic bacteria are a multi-billion Euro burden to national healthcare systems. Despite improvements in technology and medical services, morbidity and - mortality due to chronic infections have remained unchanged over the past decades. The emergence of a chronic infection disease burden calls for the development of modern diagnostics for biofilm resistance profiling and new therapeutic strategies to - eradicate biofilm-associated infections. However, many unsuccessful attempts to address this need teach us that alternative perspectives are needed to meet the challenges. - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - COMBAT - - - ERC-2016-COG - - - 724290 - - - - - WEIZMANN INSTITUTE OF SCIENCE - WEIZMANN INSTITUTE OF SCIENCE - - - EUR 2 484 722 - - - Single-molecule spectroscopy of coordinated motions in allosteric proteins - - - EUR 2 484 722 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Critical for the function of many proteins, allosteric communication involves transmission of the effect of binding at one site of a protein to another through conformational changes. Yet the structural and dynamic basis for - allostery remains poorly understood. In particular, there is no method to follow coordinated large-scale motions of domains and subunits in proteins as they occur. Since the subunits of allosteric proteins often contain multiple domains, any such - method entails probing the dynamics along several intra-protein distances simultaneously. - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Israel - - - SMALLOSTERY - - - ERC-2016-ADG - - - 742637 - - - - - THE HEBREW UNIVERSITY OF JERUSALEM - THE HEBREW UNIVERSITY OF JERUSALEM - - - EUR 2 000 000 - - - Speleothems paleoclimate: accounting for isotopic disequilibrium - - - EUR 2 000 000 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Understanding and quantifying the impacts of climate change at the regional and hemispheric scales are particularly difficult with respect to changes in rainfall and temperature patterns that lead to extended droughts and - flooding events. Isotopic records in speleothems are increasingly used to determine climate variability on land and for data-model comparisons. However, transferring speleothem records into quantitative climate parameters suffers from a major - limitation: speleothem formation processes result in geochemical disequilibrium and there is currently no way to correct for it in paleoclimate data. SPADE will shift the treatment of paleoclimate archives from regarding them as recorders of slow - geological processes to consideration of geological material as recording much faster chemical reactions. As such, they cannot be assumed to form at equilibrium. SPADE will create a new framework, based on one classic and two novel isotopic tracers - in carbonates (δ18O-Δ17O-Δ47) to quantify disequilibrium in cave records and overcome this underlying limitation. SPADE’s unique approach is based first on laboratory experiments that isolate chemical processes of speleothem formation, to test their - respective effects on isotopic disequilibrium. Then speleothem analog experiments and modern cave material are combined to create speleothem specific calibrations for these isotopic proxies. These SPADE results will then be applied to classic - paleoclimate records of dryland hydrology, such as Soreq Cave (Israel) and Devils Hole (Nevada). SPADE will address long standing climatic hypotheses regarding the interplay between temperature, amount of rainfall, surface evaporation, moisture - sources, and regional climate connections in these drought vulnerable regions, and will make these records much more useful. A detailed understanding of disequilibrium will enable the use of these innovative geochemical tools in speleothems and more - broadly, in other paleoclimate carbonate archives. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Israel - - - SPADE - - - ERC-2016-COG - - - 724097 - - - - - KOBENHAVNS UNIVERSITET - - - EUR 212 194,80 - - - Future bio-pesticides for EU: unlocking the code of Saponin Structure-Activity Relationships for use in pest management - - - EUR 212 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - Insect pests are very damaging to worldwide food production, and there is a great demand for new environmentally-friendly bio-pesticides. Saponins are a structurally diverse class of naturally occurring plant defense compounds - that are a promising resource for novel and more sustainable pesticides. Due to their detergent-like properties, saponins can disrupt the cell membranes of herbivory pests, cause cell death, and ultimately kill them. Despite the promising potential - of saponins as bio-pesticides, little is yet known about which saponin chemical structures are toxic to which specific pest. The SSAR project aims to elucidate the relationship between saponin chemical structures and their biological activities and - evolution. First, the genes involved in the biosynthetic pathway of saponins will be identified. Then desired or novel saponins will be produced in plant tissues through metabolic engineering with the identified genes. Finally, purified saponins will - be used in bioassays with a range of pest species, to unlock the code of exactly which saponin chemical structures have a given specific biological activity. The new knowledge gained will have great industrial application potential as a generic - platform for the production of bioactive compounds from plants and their use for bio-pesticides as an alternative to chemically produced pesticides. The new bio-pesticides will both help to meet society’s need for more sustainable food production and - to contribute to the development of the knowledge based bio-economy. Identification of genes involved in saponin biosynthetic pathway will also open the possibility to engineer and breed crop with tailored saponin-based pest resistance capabilities. - The SSAR will allow me to develop as an independent and mature researcher, and extend my expertise in both academic and non-academic sectors through the training in the host institution and the collaboration with a bio-pesticide and generic - agrochemicals innovative company. - - 2018-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - SSAR - - - H2020-MSCA-IF-2014 - - - 655559 - - - - - LE STUDIUM, AGENCE REGIONALE DE RECHERCHE ET D'ACCEUIL INTERNATIONAL DE CHERCHEURS ASSOCIES - - - EUR 1 699 200 - - - SMART LOIRE VALLEY: Curiosity, Imagination and Intuition - - - EUR 3 398 400 - - - France - - - Other - - The region Centre-Val de Loire, located 130 km south of Paris, has a population of 2,5 million in an area of 40000 km². LE STUDIUM® Loire Valley Institute for Advanced Studies has its headquarters in Orleans, the capital. LE - STUDIUM®’s mission is to build the human capital for research, development and innovation in region Centre, by attracting senior foreign researchers. The SMART LOIRE VALLEY (SLV) fellowship programme is designed to enhance this regional mission and - support the regional implementation of the EU smart specialization concept. Over time it has demonstrated the benefits of outward looking research communities who adhere to the research values of LE STUDIUM®: Curiosity, Imagination and Intuition. - - 2020-10-31, ongoing project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2014-FP - Marie Skłodowska-Curie Co-funding of regional, national and international programmes (COFUND-FP) - - - MSCA-COFUND-FP - Fellowship programmes - - - France - - - SMART LOIRE VALLEY - - - H2020-MSCA-COFUND-2014 - - - 665790 - - - - - THE UNIVERSITY OF EDINBURGH - THE UNIVERSITY OF EDINBURGH - - - EUR 1 996 792 - - - Form-Independent Semantics for Natural Language Understanding - - - EUR 1 996 792 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The project addresses the most important open problem in NLP, to develop a robust semantics that is invariant across different linguistic forms within a language and across languages, and embodies aspects of common-sense - knowledge. It will be derived by machine-learning from machine-reading of vast amounts of text, using an existing state-of-the-art wide-coverage CCG semantic parser developed under previous ERC funding to the PI, initially to build traditional - semantic analyses of sentences relating named entities. - - 2022-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - SEMANTAX - - - ERC-2016-ADG - - - 742137 - - - - - STATENS MUSEUM FOR KUNST - - - EUR 200 194,80 - - - Netherlandish Paintings in Ledreborg Palace: A Multi-Disciplinary Research of circa 600 Paintings - - - EUR 200 194,80 - - - Denmark - - - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - More than 600 Netherlandish seventeenth century paintings decorate the walls of Ledreborg Palace (Lejre, Denmark). The painting collection, of which a large share presumably was brought together in the first half of the - eighteenth-century, consists mostly of mass-produced paintings, a novel commodity of the seventeenth century. Fascinatingly, Ledreborg Palace is not the only collection in Denmark which displays a strong emphasis on Netherlandish paintings: at least - 2 other (also not disclosed) collections are known. However, the question why the Danish seem to have had a strong interest in Netherlandish paintings remains unanswered. - - - 2019-04-24, ongoing project - - - 2017-04-25 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-SE - Society and Enterprise panel - - - Denmark - - - NePLeP - - - H2020-MSCA-IF-2016 - - - 753496 - - - - - EUROPEAN SOCIAL SURVEY EUROPEAN RESEARCH INFRASTRUCTURE CONSORTIUM - - - EUR 2 367 888 - - - European Social Survey Sustainability - - - EUR 2 367 888 - - - United Kingdom - - - Research Organisations - - The societal challenges affecting European societies require responsive socio-economic policy solutions. The European Social Survey is an unparalleled resource enabling stability and change in Europeans’ social attitudes to be - charted. Its value for science and public policy has been recognised. However, despite such recognition and the clear success and impact of the European Social Survey research infrastructure, culminating in the award of ERIC status in 2013, there - remain significant challenges to ensuring its long-term sustainability. ESS-SUSTAIN represents a comprehensive response to the different challenges and it will be instrumental in securing the sustainable future of ESS ERIC. A key challenge is - ensuring the appropriate number of European countries are included, representing the different areas of geographic Europe. This is a critical requirement for meaningful analyses beyond the national level, as well as for the financial viability of the - infrastructure. The most important activities in this proposal are therefore those which aim (i) to enhance the long-term commitment of existing Members and Observers of ESS ERIC, (2) effect the transfer of the current guest status of some countries - to more stable memberships and (3) expand the coverage of the ESS to countries not yet affiliated. Based upon the current number of just over twenty countries participating in the ESS ERIC, a further increase of its membership will translate into - lower costs of participation for all, whilst also strengthening the analytical power of its datasets. - - 2018-03-31, ongoing project | - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.1."> - - - INFRADEV-3-2015 - Individual implementation and operation of ESFRI projects - - - RIA - Research and Innovation action - - - United Kingdom - - - ESS-SUSTAIN - - - H2020-INFRADEV-1-2015-1 - - - 676166 - - - - - UNIVERSITE GRENOBLE ALPES - - - EUR 1 962 000 - - - Grenoble Quantum Engineering Doctoral Programme - - - EUR 3 924 000 - - - France - - - Higher or Secondary Education Establishments - - Quantum engineering is a novel domain of research, built on fundamental research carried out in the last 20 years all over the world. Quantum technologies offer radically new materials and devices for the next century, in - sectors such as security, energy, communications, or healthcare. To transform such disruptive scientific concepts into real life benefits it is crucial to develop research aiming at higher technology readiness levels. To ensure that Europe takes the - leadership in this coming quantum revolution, we must train next generation quantum engineers, by offering doctoral training in interconnected domains with the highest scientific standards, while equally providing an opening to the industrial world. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2016 - Co-funding of regional, national and international programmes - - - MSCA-COFUND-DP - Doctoral programmes - - - France - - - GreQuE - - - H2020-MSCA-COFUND-2016 - - - 754303 - - - - - COURTAULD INSTITUTE OF ART - - - EUR 195 454,80 - - - Worldly Matter: The Materials of Conceptual Art - - - EUR 195 454,80 - - - United Kingdom - - - Other - - The aim of this project is to re-evaluate established narratives of Conceptual Art in North America and Western Europe and their global context. It will examine the importance of materiality and subject matter – or “worldly - matters”, to borrow Conceptual artist Douglas Huebler’s term – for Conceptual Art in the 1960s and early 1970s. Engaging with theories of conservation as well as the most recent discourses around materiality, the project combines a genuinely art - historical objective, oriented towards the reconstruction of historical contexts, with broader theoretical perspectives. By studying artistic practices in-depth and reconstructing historical debates, it will make an important contribution to the - history of Conceptual Art, and hence the immediate prehistory and preconditions of today’s cultural production. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - WorldlyMatter - - - H2020-MSCA-IF-2016 - - - 753815 - - - - - KING'S COLLEGE LONDON - - - EUR 183 454,80 - - - Role of Cdc42 in cancer cell adhesion to endothelial cells and platelets - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Metastasis accounts for 90% of cancer deaths, and it is therefore important and timely to identify new therapeutic targets aimed specifically at metastasis. Cdc42 has recently been implicated in a key step of the metastatic - cascade: the extravasation of circulating tumour cells, also termed transendothelial migration (TEM) . This project aims to study how Cdc42 contributes to breast cancer cell TEM in vitro and in vivo. Cdc42 regulates β1‐integrin expression via the - transcription factor serum response factor (SRF) and thereby stimulates cancer cell adhesion to endothelial cells (ECs) and TEM. To analyse the molecular basis for this regulation, downstream targets of Cdc42 will be depleted by RNAi in a panel of - breast cancer cells to determine which target/s are responsible for altering β1‐integrin expression, adhesion to ECs or TEM. - - 2017-05-10, Grant Agreement terminated - - - 2015-05-11 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - Cdc42Adhere - - - H2020-MSCA-IF-2014 - - - 655817 - - - - - UNIVERSITAT POLITECNICA DE CATALUNYA - SWANSEA UNIVERSITY - ECOLE CENTRALE DE NANTES - VOLKSWAGEN AG - SIEMENS PLC - AIRBUS SAS - AIRBUS GROUP SAS - ESI GROUP - - - EUR 2 080 164,96 - - - Empowered decision-making in simulation-based engineering: Advanced Model Reduction for real-time, inverse and optimization in industrial problems - - - EUR 2 080 164,96 - - - Spain - United Kingdom - France - Germany - United Kingdom - France - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - “AdMoRe: Empowered decision-making in simulation-based engineering: Advanced Model Reduction for real-time, inverse and optimization in industrial problems” aims at providing in-depth training of Early Stage Researches (ESRs) - in the development and application of state-of-the-art computational models and numerical methods to solve cutting-edge engineering problems. The main driving factors of all the beneficiaries are reduced order modeling techniques for real-time, - inverse and optimization problems. In fact, these issues are seen by industry as a major asset to increase performance and competitiveness. The ultimate goal is to produce the next generation of European research engineers, leaders in the use of - these methodologies for industry related problems. - - 2019-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Spain - - - AdMoRe - - - H2020-MSCA-ITN-2015 - - - 675919 - - - - - SWANSEA UNIVERSITY - UNIVERSIDAD DE OVIEDO - UNIVERSITA DEGLI STUDI DI FIRENZE - FUNDACION AZTI - AZTI FUNDAZIOA - NATURAL RESOURCES BODY FOR WALES - NEMO Nature and Environment Management Operators S.r.l - NEOALGAE MICRO SEAWEEDS PRODUCTS SL - - - EUR 2 079 605,16 - - - AQUAtic INVAders: Early Detection, Control and Management - - - EUR 2 079 605,16 - - - United Kingdom - Spain - Italy - Spain - United Kingdom - Italy - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Aquatic Invasive Species (AIS) are on the rise due to the synergistic effects of climate change and habitat destruction. The impacts of AIS on Biodiversity, human health, and loss of ecosystem services are well known, but - their control and management has now become a worldwide priority. Successful management of AIS is challenging because it requires several steps in succession: (1) early detection, (2) identification of routes of introduction and pathways of - dispersal, and (3) development of efficient control measures. However, public awareness and stakeholder involvement are also critical .The main research goal of AQUAINVAD-ED is to exploit novel molecular advances combined with the power of citizen - science to develop innovative methods of early detection, control and management of AIS. This will be achieved via a multi-disciplinary network of experts in invasion biology, aquatic biotechnology, citizen science and environmental policy working - from 3 different countries. The inter-sectoral dimension of the consortium consists of fundamental and applied scientists from 3 universities, 1 technological institute, 2 government agencies, 1 NGO and 5 SMEs. AQUAINVAD-ED will catalyse research and - commercial activity in the detection and management of AIS, as well as in the implementation of codes of good practice for the European industry and Government agencies. This will be achieved by training the next generation of researchers on the - principles of invasion biology, providing them with the skills necessary to detect and quantify the ecological and socio-economic impacts of AIS and the ability to communicate science to the general public. The training program will be delivered - through individual research projects, active participation in network activities and a unique combination of specialised courses, designed to increase employability in the consultancy sector, government, academia, and the water industry. - - 2019-05-31, ongoing project | - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - AQUAINVAD-ED - - - H2020-MSCA-ITN-2014 - - - 642197 - - - - - UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA - - - EUR 180 277,20 - - - Development of Fast Timing tools for Event Reconstruction at the high luminosity frontier - - - EUR 180 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - High luminosities at future particles colliders, such as the High Luminosity Large Hadron Collider (HL-LHC), will come at the price of a dramatic increase in the number of concurrent interactions of beam particles (referred to - as pileup) per crossing in the experiments, implying serious challenges to the reconstruction of events. Due to the spread of the proton bunches along the beamline, collisions vertices at the HL-LHC are spread out over about 5 cm along the beam - direction and about 160 ps in time. At the vertex densities foreseen at the HL-LHC, some vertices and the associated particles are so close to be merged by the track reconstruction forming fake jets of high transverse momentum. Moreover, the random - overlap of energy deposits from neutral particles (mainly photons), that cannot be tied via a track to any vertex, will deteriorate the calorimeter performance in terms of energy measurement and particle identification, as particles appear to be less - isolated. A promising tool advocated to mitigate the effects of pileup consists in complementing the high transverse (spatial) granularity of the detectors with extreme time resolution (of the order of 10 ps), that would allow energy deposits coming - from different interaction vertices to be resolved in time. - - 2018-04-30, Grant Agreement terminated - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - FasTER - - - H2020-MSCA-IF-2015 - - - 707080 - - - - - ISTANBUL TEKNIK UNIVERSITESI - - - EUR 145 845,60 - - - Fate and Toxic Effects of Silver Nanoparticles and Its Transformation Products in Soil Applied with Biosolids - - - EUR 145 845,60 - - - Turkey - - - Higher or Secondary Education Establishments - - Sewage sludge management is one of the most challenging waste issues in Environmental Engineering field due to their highly polluted nature and high volume. On the other hand, sewage sludge, which is also called as biosolids, - can be a nutrient resource for the agri-foods which leads to their usage in agriculture as fertilizers. Usage of biosolids as fertilizer is the most desirable management strategy since it provides resource recovery and prevents the usage of synthetic - chemicals which can be harmful for human and environment health. Therefore, after the treatment of biosolids to meet the required quality criteria, their ultimate disposal as fertilizer has to be sustained. Up to date, organic, metallic or hazardous - pollutants were addressed to be removed from biosolids before land spreading and standards were defined in regulations. However, there are new concerning pollutants for biosolids application to agricultural lands. One of the most recent and biggest - concerns is the presence of silver nanoparticles (AgNPs), which are widely used as biocides in the consumer products and are shown to occur in wastewater treatment plants, mostly, in biosolids. They are, as a source of ionic and nano Ag, among the - emerging pollutants which are known to have potential to pose threat to human and environment health and have not been included in monitoring lists, yet. Therefore, the aim of this research is to advance the state of the art in land spread of - biosolids through the investigation of the toxic effects and bioacculumation of AgNPs and its transformation products in soil organisms. For excellence in research, the knowledge about the toxic effects is integrated with environmental risk - assessment which will enable necessary actions such as proposing guidelines for biosolids applications. - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Turkey - - - TESNinSAB - - - H2020-MSCA-IF-2015 - - - 704803 - - - - - UNIVERSITE LYON 1 CLAUDE BERNARD - - - EUR 232 160,40 - - - Mechanistic studies of long chain omega-3 fatty acid supplementation and inflammation in metabolic syndrome. - - - EUR 232 160,40 - - - France - - - Higher or Secondary Education Establishments - - Subclinical inflammation is a key factor in the development of cardiovascular diseases. Obesity and metabolic syndrome (MetS), both diet and lifestyle-related, are highly prevalent causes of subclinical inflammation. A growing - body of literature suggests that dietary long chain omega-3 polyunsaturated fatty acids (LCn-3PUFA) may attenuate MetS-associated pro-inflammatory state. However, it remains unclear whether the different LCn-3PUFA, primarily docosahexaenoic acid - (DHA) and eicosapentaenoic acid (EPA), have similar effects on pro-inflammatory processes because most previous studies used them in mixture. Whether efficacy of LCn-3PUFA is influenced by sex/gender is also unknown. - - - 2020-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - France - - - PIMS - - - H2020-MSCA-IF-2015 - - - 705913 - - - - - SWANSEA UNIVERSITY - - - EUR 183 454,80 - - - POLICY INNOVATION AND LEGITIMACY IN REGIONAL MULTI-LEVEL GOVERNANCE - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Multi-level policy-making between EU, national and sub-national levels has become increasingly complex. This has created the need for innovative governance solutions to address this complexity, which in turn has had an effect - on political legitimacy. This project aims to address this topic by developing the linkages between procedural innovation in governance and the legitimacy of these processes in a multi-level political context, looking at how (or whether) political - legitimacy can travel between governmental levels. The main research questions that will be addressed are: - - 2017-09-06, closed project - - - 2015-09-07 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - MLGPIL - - - H2020-MSCA-IF-2014 - - - 661479 - - - - - DANMARKS TEKNISKE UNIVERSITET - - - EUR 212 194,80 - - - A Biomimetic Learning Control Scheme for control of Modular Robots - - - EUR 212 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - Motor control is a very important feature in the human brain for the performance of a motor skill. The biological basis of this feature can be better understood by emulating the cerebellar mechanisms of learning. The - cerebellum plays a key role in implementing fine motor control, since it extracts the information from sensory-motor signals and uses it to respond to the environment. The purpose of this project is to benefit from the interplay between a body agent - and an embodied artificial brain to understand the role of the first in the behavior of the latter and vice versa. The project aims to build a novel bio-inspired computational learning model for modular robots, and to incorporate it into a - biologically plausible control scheme. The aforementioned model will merge machine learning techniques and a spiking modular cerebellum to develop a process that leads to the formation of long-term motor memories. Novel modular robots, such as Fable, - will benefit from this adaptive predictive control system to perform desired, task-fulfilling behaviors. Exploiting this approach, the project pursues the discovery of important insights into the modular structure of the cerebellum, and its - involvement in processing the sensory input for motor control tasks. The project will be developed at DTU with a run time of two years and will benefit from collaborations with other research groups (UGR and TUM). Their long expertise in neuromorphic - computing and spiking networks will ensure that the candidate receives scientific training related to these fields (e.g. about cerebellar topology and cellular properties, and implementation of spiking networks in hardware). By providing multiple - relevant contributions across the spectrum of the H2020 objectives in terms of its potential to advance robotic manufacturing, brain processing understanding, and novel computing paradigms, this project will enable the candidate to enhance her - position at the forefront of advances in this fields. - - 2019-01-31, ongoing project - - - 2017-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - BIOMODULAR - - - H2020-MSCA-IF-2015 - - - 705100 - - - - - UNIVERSITEIT LEIDEN - UNIVERSITEIT LEIDEN - - - EUR 1 975 200 - - - Set in Stone - A retrospective impact assessment of human and environmental resource usage in Late Bronze Age Mycenaean Monumental Architecture, Greece - - - EUR 1 975 200 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Greek Mycenaean monumental architecture has been well-studied. However, the extent to which large-scale building programmes contributed to the socioeconomic and political changes and crises that took place in Late Bronze Age - Greece (c.1600-1100/1070 BC) has not been studied. The project aims to investigate human and natural resources which interacted in the Argive Plain and Attica. There, elites mobilized these resources to implement their monumental building programmes. - It seeks to reveal how and why these constructions were accomplished, and what impact such large-scale prolonged building programmes had on the population over time. Methodologically, practical building processes and inherent social practices are - captured via the chaîne opératoire approach. Economic data are assessed via architectural energetics, an econometric modelling procedure translating buildings into cost-estimates including time-units of labour invested. These two approaches are - triangulated with critically reviewed data sets revealing the changing broader demographic situation of the region. The latter data are extracted from published settlement and land use surveys, as well as archaeobotanical, geomorphological, climatic - and mortuary studies from the Argolid. Published historical archives and the Linear B tablets provide further comparative data on regional pre-industrial land use and human activities. - - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - SETinSTONE - - - ERC-2014-CoG - - - 646667 - - - - - ISTANBUL TEKNIK UNIVERSITESI - UNIVERSITA DEGLI STUDI DI MILANO - IROC TECHNOLOGIES SA - KARLSRUHER INSTITUT FUER TECHNOLOGIE - INSTITUT POLYTECHNIQUE DE GRENOBLE - - - EUR 643 500 - - - Synthesis and Performance Optimization of a Switching Nano-crossbar Computer - - - EUR 724 500 - - - Turkey - Italy - France - Germany - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The main goal of this project is developing a complete synthesis and optimization methodology for switching nano-crossbar arrays that leads to the design and construction of an emerging nanocomputer. New computing models for - diode, FET, and four-terminal switch based nanoarrays are developed. The proposed methodology implements both arithmetic and memory elements, necessitated by achieving a computer, by considering performance parameters such as area, delay, power - dissipation, and reliability. With combination of arithmetic and memory elements a synchronous state machine (SSM), representation of a computer, is realized. The proposed methodology targets variety of emerging technologies including - nanowire/nanotube crossbar arrays, magnetic switch-based structures, and crossbar memories. The results of this project will be a foundation of nano-crossbar based circuit design techniques and greatly contribute to the construction of emerging - computers beyond CMOS. - - - 2019-11-30, ongoing project - - - 2015-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Turkey - - - NANOxCOMP - - - H2020-MSCA-RISE-2015 - - - 691178 - - - - - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - UNIVERSIDAD DE ALCALA - UNIVERSITAT POLITECNICA DE VALENCIA - VRIJE UNIVERSITEIT BRUSSEL - TEL AVIV UNIVERSITY - LEIBNIZ-INSTITUT FUER PHOTONISCHE TECHNOLOGIEN E.V. - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - RISE ACREO AB - FIBERCORE LIMITED - AGENCE NATIONALE POUR LA GESTION DES DECHETS RADIOACTIFS - - - EUR 3 880 324,44 - - - Fibre Nervous Sensing Systems - - - EUR 3 880 324,44 - - - Switzerland - Spain - Spain - Belgium - Israel - Germany - United Kingdom - Sweden - United Kingdom - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - - The unprecedented properties of optical fibres make them ideal to be implemented as 'artificial nervous systems', enabling any tool or structure to become a sensitive and smart object. Conventional optical fibres are small, - low-cost and can be seamlessly integrated in materials, in engineering structures and in the environment. By exploiting the most advanced light-matter interactions, these tiny luminous wires can realize distributed sensing, which means that each - point along an optical fibre can separately and selectively sense quantities such as temperature, strain, acoustic waves and pressure, in perfect similarity to a real organic nerve. - - 2020-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Switzerland - - - FINESSE - - - H2020-MSCA-ITN-2016 - - - 722509 - - - - - JOHNSON MATTHEY PLC - - - EUR 183 454,80 - - - Directed Evolution of Enzyme for Applied Biocatalysis at Ultrahigh Throughput in Picoliter Droplets - - - EUR 183 454,80 - - - United Kingdom - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Enzymes have established as a new class of catalysts in the field of modern synthetic chemistry and continue to gain in importance. Directed evolution is currently one of the most promising approaches aiming at enzymes with - desired catalytic activities and it's potentially directly correlates with the library size that can be screened. One of the most powerful approaches to overcome these limitations is arguable the recently introduced microfluidic droplet technology; - this methodology not only allows to quickly screen millions of clones in a cost effective manner, but is also broadly applicable since fluorometric as well as colorimetric assays can be used. Interestingly, even though numerous publication highlight - its potential, an unambiguous evidence of its ability to provide synthetically relevant biocatalysts still needs to be furnished. In addition, access to this technology is currently limited to a few academic research groups and thus, this approach - requires further implementation to evolve as an easily manageable lab routine in the near future. - - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-SE - Society and Enterprise panel - - - United Kingdom - - - TreasureDrop - - - H2020-MSCA-IF-2016 - - - 752435 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - UNIVERSITY OF ULSTER - SYDDANSK UNIVERSITET - SPIRITAN ASYLUM SERVICES INITIATIVE LIMITED - THE DUBLIN RAPE CRISIS CENTRE LIMITED - Police Service of Northern Ireland - PROBATION BOARD OF NORTHERN IRELAND - ODENSE KOMMUNE - DANSK RODE KORS (DANISH RED CROSS) - - - EUR 3 316 177,44 - - - COllaborative Network for Training and EXpertise in psychoTraumatology - - - EUR 3 316 177,44 - - - Ireland - United Kingdom - Denmark - Ireland - Ireland - United Kingdom - United Kingdom - Denmark - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - Other - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Other - - Mental health disorders afflict more than one-third of the EU’s population each year with an annual economic cost to the EU of €432 billion. The ‘COllaborative Network for Training and EXcellence in psychoTraumatology’ - (CONTEXT) is an international, interdisciplinary European Industrial Doctorate (EID) designed to address deficiencies in psychotraumatology training and innovation. A key feature of CONTEXT is the minimum 50% secondment of each ESR to the - non-academic sector. Consistent with the requirements of an EID, this component grants ESRs access to populations not otherwise accessible in standard doctoral training programmes. This design will facilitate a new cohort of researchers and - practitioners who can translate research into practice, thereby mitigating the impact of psychotrauma in the EU. The goal of CONTEXT is to develop a high quality, innovative research training programme to build capacity and expertise, and foster - innovative practice and social enterprise in the area of psychotraumatology. The nine beneficiaries of CONTEXT represent a diverse, interconnected, intersectoral consortium, well placed to collaboratively train and supervise the 12 ESRs. Three - interconnected research work packages, each targeting a priority population in Europe (EU-based asylum seekers and refugees, WP3; emergency-service personnel and humanitarian first-responders, WP4; and victims and perpetrators of childhood- and - gender-based violence, WP5), address current and emergent skill and professional deficiencies that are essential in curbing the adverse social consequences of trauma-related psychological distress within the EU. CONTEXT enjoys significant support and - commitment from highly regarded, international stakeholders and influencers at the political, scientific, and professional level. - - 2020-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-EID - European Industrial Doctorates - - - Ireland - - - CONTEXT - - - H2020-MSCA-ITN-2016 - - - 722523 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 2 246 536 - - - Criticality and Dual Superfluidity - - - EUR 2 246 536 - - - France - France - - - Research Organisations - Research Organisations - - Low temperature matter exhibits a spectacular variety of highly ordered states that occur through phase transitions. In quantum systems, phase transitions and associated critical phenomena constitute a central issue of modern - physics. Wilson’s theory of renormalization showed that very different physical systems could be unified under the same universality class characterized by critical exponents. The high degree of control offered by ultracold atom experiments sets them - as an ideal platform for the investigation of phase transitions and critical phenomena. - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - France - - - CRITISUP2 - - - ERC-2016-ADG - - - 743159 - - - - - DANMARKS TEKNISKE UNIVERSITET - - - EUR 212 194,80 - - - Dynamic performance modelling and controller design of a mini-scale organic Rankine cycle unit for heavy duty vehicles - - - EUR 212 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - Internal combustion engines of heavy duty vehicles convert only approximately 40 % of the combustion heat to mechanical power, while rest of the heat is rejected into the environment as waste heat. An organic Rankine cycle - unit that recovers part of this waste heat is expected to reduce the fuel consumption and carbon dioxide emissions by about 15 % of the heavy duty vehicle. However, the waste heat from internal combustion engines of heavy duty vehicles is - characterized by large fluctuations in load, making it a challenging task to control an organic Rankine cycle unit in an efficient, safe and cost-effective manner. A few prototype of mini organic Rankine cycle units for truck applications have been - tested, but no commercial products are available; the aforementioned control challenge being the major barrier for their commercialization. The primary objective of DYNCON-ORC is to develop an appropriate controller for a mini-scale organic Rankine - cycle unit for waste heat recovery from internal combustion engines of heavy duty vehicles. Advanced numerical models of the organic Rankine cycle unit including its components will be developed for simulation of the steady state and dynamic - operational conditions. Based on the results of the dynamic model, a non-linear model predictive controller will be designed and optimized. The numerical models will be experimentally validated and implemented on a real organic Rankine cycle system. - Through the collaboration with international, world-leading partners from industry and academia it is ensured that the project will be successfully completed and that the findings of the project will be transferred to and implemented in industry. In - broader terms, the project will contribute to the development of a more efficient energy system for vehicles, reducing the fuel consumption and carbon dioxide emissions of the transportation sector, thus helping to attain socio-economic and - environmental targets in context of the EU 2020 vision. - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - DYNCON-ORC - - - H2020-MSCA-IF-2016 - - - 751947 - - - - - VILNIAUS UNIVERSITETAS - VILNIAUS UNIVERSITETAS - - - EUR 2 499 875 - - - Single-cell temporal tracking of epigenetic DNA marks - - - EUR 2 499 875 - - - Lithuania - Lithuania - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Over the past decade, epigenetic phenomena have taken centre stage in our understanding of gene regulation, cellular differentiation and human disease. DNA methylation is a prevalent epigenetic modification in mammals, which - is brought about by enzymatic transfer of methyl groups from the S-adenosylmethionine (SAM) cofactor by three known DNA methyltransferases (DNMTs). The most dramatic epigenomic reprogramming in mammalian development occurs after fertilization, - whereby a global loss of DNA methylation is followed by massive reinstatement of new methylation patterns, different for each cell type. Although DNA methylation has been extensively investigated, key mechanistic aspects of these fascinating events - remain obscure. The goal of this proposal is to bridge the gap in our understanding of how the genomic methylation patterns are established and how they govern cell plasticity and variability during differentiation and development. These questions - could only be answered by precise determination of where and when methylation marks are deposited by the individual DNMTs, and how these methylation marks affect gene expression. To achieve this ambitious goal, we will metabolically engineer mouse - cells to permit SAM analog-based chemical pulse-tagging of their methylation sites in vivo. We will then advance profiling of DNA modifications to the single cell level via innovative integration of microdroplet-based barcoding, precise genomic - mapping and super-resolution imaging. Using this unique experimental system we will determine, with unprecedented detail and throughput, the dynamics and variability of DNA methylation and gene expression patterns during differentiation of mouse - embryonic cells to neural and other lineages. This project will give a comprehensive, time-resolved view of the roles that the DNMTs play in mammalian development, which will open new horizons in epigenomic research and will advance our understanding - of human development and disease. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Lithuania - - - EpiTrack - - - ERC-2016-ADG - - - 742654 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 2 235 815 - - - Spatiotemporal organisation of bacterial outer membrane proteins - - - EUR 2 235 815 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The outer membrane (OM) of Gram-negative bacteria protects against environmental insult and is central to pathogenesis hence finding ways to disrupt its integrity is a route towards new antibiotics. However, our understanding - of OM biology is limited. In particular, how the OM is organised is largely unknown. My laboratory recently discovered spatiotemporal Outer Membrane Protein organisation (OMPorg) in Escherichia coli, a new organising principle that explains how OMPs - are turned over. We found that OMPs cluster into islands that can be mimicked in supported bilayers using purified proteins. As cells grow, OMP islands are displaced to the poles by new islands, leading to binary partitioning of old OMPs in - repository cells following septation. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - OMPorg - - - ERC-2016-ADG - - - 742555 - - - - - MAGYAR TUDOMANYOS AKADEMIA RENYI ALFRED MATEMATIKAI KUTATOINTEZET - MAGYAR TUDOMANYOS AKADEMIA RENYI ALFRED MATEMATIKAI KUTATOINTEZET - - - EUR 1 965 340 - - - Growth in Groups and Graph Isomorphism Now - - - EUR 1 965 340 - - - Hungary - Hungary - - - Research Organisations - Research Organisations - - "In recent years there has been spectacular progress in studying growth in groups. A central result in this new area, obtained by Pyber-Szabo' (with a similar result proved by Breuillard-Green-Tao), shows that powers of - generating subsets of finite simple groups of "bounded dimension" grow fast. Extending this Product Theorem Szabo' and the PI also proved a weaker version of a conjecture of Helfgott-Lindenstrauss. The Product Theorem has deep consequences in the - study of groups, number theory and random walks. A central open question of the area is to remove the dependence on dimension in our Product Theorem. The PI formulated a new Conjecture, as a step forward. The way to further progress is via combining - techniques from asymptotic group theory and probability theory. It is from this perspective that the current GROGandGIN proposal addresses issues concerning random walks. We examine how recent probabilistic arguments for random walks in the symmetric - group may be transferred to matrix groups. While the first results in the subject of growth concern matrix groups we see an evolving theory of growth in permutation groups. This relies on earlier work of Babai and the PI which aims at finding proofs - which do not use the Classification of Finite Simple Groups (CFSG). Similarly, Babai's famous Quasipolynomial Graph Isomorphism Algorithm builds on ideas from CFSG-free proofs due to him. The PI has recently removed CFSG from the analysis of Babai's - algorithm. Our method goes "halfway" towards removing CFSG from proofs of growth results for permutation groups, currently a major open problem. The GROGandGIN initiative plans to improve various other parts of Babai's paper, working with several - people who look at it from different angles, with an eye towards obtaining a Polynomial Graph Isomorphism algorithm. The GROGandGIN team will also study growth in Lie groups since the theory of random walks in Lie groups has been revitalised using - analogues of our Product Theorem." - - 2022-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Hungary - - - GROGandGIN - - - ERC-2016-ADG - - - 741420 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 1 999 965 - - - Nanoengineering of radioactive seeds for cancer therapy and diagnosis - - - EUR 1 999 965 - - - Spain - Spain - - - Research Organisations - Research Organisations - - One of the major challenges in modern society is the early diagnosis and treatment of diseases. Cancer is one of the most relevant diseases worldwide because of its incidence, prevalence and mortality. During the past decades, - considerable efforts have been devoted to understand the origin of the disease, find early detection methods that could improve the survival rate of cancer patients or develop treatments and devices that could reduce or eradicate cancer. The - application of nanotechnology to medicine (nanomedicine) has become one of the most promising routes for the diagnosis and treatment of diseases. The small size of nanomaterials, large surface area and high reactivity impart unique physicochemical - properties to these materials, in such a way that several therapeutics based on nanomaterials (liposomes, nanoparticles, polymers) have already been approved for clinical use in humans. However, there are still limitations that need to be overcome to - obtain novel and efficient nanocarriers for oncology applications. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Spain - - - NEST - - - ERC-2016-COG - - - 725743 - - - - - HELSINGIN YLIOPISTO - HELSINGIN YLIOPISTO - - - EUR 2 463 412 - - - Quantum Fields and Probability - - - EUR 2 463 412 - - - Finland - Finland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Quantum Field Theory (QFT) has become a universal framework in physics to study systems with infinite number of degrees of freedom. - - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Finland - - - QFPROBA - - - ERC-2016-ADG - - - 741487 - - - - - KOZEP-EUROPAI EGYETEM - KOZEP-EUROPAI EGYETEM - - - EUR 1 179 462 - - - Cognitive tomography of mental representations - - - EUR 1 179 462 - - - Hungary - Hungary - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Internal models are fundamental to our understanding of how the mind constructs percepts, makes decisions, controls movements, and interacts with others. Yet, we lack principled quantitative methods to systematically estimate - internal models from observable behaviour, and current approaches for discovering their mental representations remain heuristic and piecemeal. I propose to develop a set of novel 'doubly Bayesian' data analytical methods, using state-of-the-art - Bayesian statistical and machine learning techniques to infer humans' internal models formalised as prior distributions in Bayesian models of cognition. This approach, cognitive tomography, takes a series of behavioural observations, each of which in - itself may have very limited information content, and accumulates a detailed reconstruction of the internal model based on these observations. I also propose a set of stringent, quantifiable criteria which will be systematically applied at each step - of the proposed work to rigorously assess the success of our approach. These methodological advances will allow us to track how the structured, task-general internal models that are so fundamental to humans' superior cognitive abilities, change over - time as a result of decay, interference, and learning. We will apply cognitive tomography to a variety of experimental data sets, collected by our collaborators, in paradigms ranging from perceptual learning, through visual and motor structure - learning, to social and concept learning. These analyses will allow us to conclusively and quantitatively test our central hypothesis that, rather than simply changing along a single 'memory strength' dimension, internal models typically change via - complex and consistent patterns of transformations along multiple dimensions simultaneously. To facilitate the widespread use of our methods, we will release and support off-the-shelf usable implementations of our algorithms together with synthetic - and real test data sets. - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Hungary - - - COGTOM - - - ERC-2016-COG - - - 726090 - - - - - UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6 - UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6 - - - EUR 1 455 000 - - - The Evolution Problem in General Relativity - - - EUR 1 455 000 - - - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - General relativity has been introduced by A. Einstein in 1915. It is a major theory of modern physics and at the same time has led to fascinating mathematical problems. The present proposal focusses on two aspects of the - evolution problem for the Einstein equations which has been initiated by the pioneering work of Y. Choquet-Bruhat in 1952. - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - France - - - EPGR - - - ERC-2016-COG - - - 725589 - - - - - THE UNIVERSITY OF WARWICK - - - EUR 183 454,80 - - - Earthquake-resilient self-centering steel frame - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - An important requirement of performance-based earthquake engineering is the simultaneous control of structural and non-structural damage. Structural damage measures are related to story drifts, inelastic deformations and - residual drifts. Non-structural damage measures are related to story drifts and storey accelerations. Earthquake reconnaissance reports highlight that injuries, fatalities and economical losses related to failure of non-structural components far - exceed those related to structural failures. Moreover, explicit consideration of non-structural damage becomes vital in the design of critical facilities such as hospitals carrying acceleration-sensitive medical equipment, which have to remain - functional in the aftermath of an earthquake. Structural and non-structural damage results in direct and indirect losses such as repair costs and costly downtime during which the building is repaired and cannot be used or occupied. Therefore, there - is an urgent need for minimal-damage structures that can truly achieve seismic resilience. - - - 2017-08-30, closed project - - - 2015-08-31 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - EQRESFRAME - - - H2020-MSCA-IF-2014 - - - 654426 - - - - - TECHNISCHE UNIVERSITAT DORTMUND - TECHNISCHE UNIVERSITAT DORTMUND - - - EUR 1 979 679 - - - Programmable Readers, Writers, and Erasers of the Epigenetic Cytosine Code - - - EUR 1 979 679 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Human DNA contains two types of biologically instructive information: the canonical nucleobases A, G, T, C, and the epigenetic nucleobases mC, hmC, fC, and caC. Canonical nucleobases encode the identity of all RNAs and - proteins that are synthesized by a cell, whereas epigenetic nucleobases regulate this synthesis. This regulation shapes the phenotype of cells, and its perturbation is a key trigger of cancer. - - 2022-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - EPICODE - - - ERC-2016-COG - - - 723863 - - - - - UNIVERSITY OF GLASGOW - - - EUR 146 591,10 - - - Psychiatric spaces in transition: discourse, dwelling, doing - - - EUR 146 591,10 - - - United Kingdom - - - Higher or Secondary Education Establishments - - To ask searching questions about changes in the treatment of people with mental health problems - about the extent to which they experience the right mix of 'protective' and 'empowering' support - is to probe deeply into the - 'humanity' of European society. Responding to this challenge, the proposed action will combine in-depth investigation into the near-unique 'laboratory' of psychiatric transition offered by one site in Scotland, Gartnavel Royal Hospital, Glasgow, with - an explicitly comparative framing derived from research on equivalent shifts occurring in Sweden. A multi-disciplinary research team, working across human geography, planning-architecture and clinical psychiatry, will deploy a range of engaged, - qualitative research methods: interviewing, focus groups, walking tours, drawing work and directed photography, coupled to both standard and more experimental techniques for 'data' interpretation. Based on this research, the team will develop - conceptual resources for a 'model' of European psychiatric transition, notably from institutional (asylum/hospital) to de-institutional or trans-institutional landscapes of mental health care. More empirically, the objective is to recover subjective - experiences of the changing spaces of Gartnavel as felt, understood and represented by different cohorts of patients and staff (past and present), gathering these materials into a 'living archive' - available on-line and via an exhibition/event - to - be made available to all connected with the site, local residents neighbouring the site and a wider public concerned with mental health matters. Through both this impact work and scholarly outputs, a further objective is critically to appraise - psychiatric transition, and in particular to re-evaluate the notion of 'the asylum' in an era arguably drifting back to accepting in-patient care for categories of chronic, acute and (allegedly) 'dangerous' patients. - - 2018-06-30, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - GART-PSYSPAC - - - H2020-MSCA-IF-2015 - - - 706026 - - - - - UNIVERSIDADE DE AVEIRO - GLOBAZ, S.A. - - - EUR 154 125 - - - Science@Aveiro, General public and researchers – Closing the Gap. - - - EUR 154 125 - - - Portugal - Portugal - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - It’s our intention to organize the 9th and 10th edition of the Researchers’ Night initiative – The Science@Aveiro, General public and researchers – Closing the Gap. We propose two events for 2014 and 2015, around the themes of - “Materials” and “Light” respectively. Besides the different themes, this integrated edition will not forget the fact that in 2015 the Researchers Nigth’ initiative will celebrate their 10th anniversary. To celebrate that, in 2014 we will launch the - “Competition 10th anniversary of Researchers’ Night”, involving categories on drawing, photography and video. This competition is on the theme “Research is everywhere” and it is dedicated to the general public but we expect more in impact at the - students’ community. - - 2015-12-31, closed project | - - - 2014-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.5."> - - - MSCA-NIGHT-2014 - European Researchers' Night (NIGHT) - - - CSA - Coordination and support action - - - Portugal - - - Science at Aveiro - - - H2020-MSCA-NIGHT-2014 - - - 633219 - - - - - TECHNISCHE UNIVERSITAT DORTMUND - TECHNISCHE UNIVERSITAT DORTMUND - - - EUR 1 994 791 - - - Coherent optical control of multi-functional nano-scale hybrid units - - - EUR 1 994 791 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In the physics and chemistry of materials science, an intense focus of forefront research is the search for ever-smaller and ever-faster building blocks for information and communication technology (ICT) applications. The - realization of next-generation devices, in ICT fields such as spintronics, spin-orbitronics and plasmonics, will depend decisively on our ability to generate new functionalities that can be actively controlled on the shortest length and time scales. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - hyControl - - - ERC-2016-COG - - - 725767 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - - - EUR 6 088 800 - - - Cutting Edge Training - Cutting Edge Technology - - - EUR 12 177 600 - - - Ireland - - - Higher or Secondary Education Establishments - - EDGE is a training and development programme of scientific excellence for postdoctoral researchers that offers a unique combination of disciplines and industry engagement to the 71 fellows it will recruit. Leveraging the - strengths and assets of three Irish National Research Centres, AMBER, CONNECT and ADAPT, headquartered in TCD, EDGE will form the next generation of thought leaders in ICT. AMBER offers expertise in advanced materials that will play a pivotal role in - future systems and devices. CONNECT’s focus is on future networks that will underpin the services the world needs and ADAPT brings cutting-edge expertise in digital content. EDGE researchers will work at the interface between these Centres and will - generate highly interdisciplinary projects, adding value to all. Most importantly, industry will have a primary role in defining, running and supporting the projects, and will take an active part in developing the scientists, through secondments, - industry events and specialised training. - - - 2021-05-31, ongoing project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2015-FP - Marie Skłodowska-Curie Co-funding of regional, national and international programmes (COFUND-FP) - - - MSCA-COFUND-FP - Fellowship programmes - - - Ireland - - - EDGE - - - H2020-MSCA-COFUND-2015 - - - 713567 - - - - - AN TUDARAS UM ARD OIDEACHAS - - - EUR 4 602 000 - - - Collaborative Research Fellowships for a Responsive and Innovative Europe - - - EUR 9 204 000 - - - Ireland - - - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - The CAROLINE Fellowship Programme proposed by the Irish Research Council (IRC) will provide a unique opportunity for researchers to further develop their skills, competencies and experience through inter-sectoral collaboration - with NGOs and International Organisations (IO). Proposals will be invited from all disciplines that speak to the overarching theme of global sustainable development as set out under the United Nations 2030 Agenda for shared economic prosperity, - social development, and environmental protection. CAROLINE will fund 50 experienced researchers across two modes; International Fellowships (three-year) and Irish Fellowships (two-year). The IRC, a national agency, funds excellent research across all - disciplines. Unique aspects of CAROLINE include the European and global resonance of the overarching research theme, the inclusion of NGO and IO partners with the host research performing organisations, flexibility in secondments, comprehensive - approaches to equal opportunities and gender aspects, and dedicated core training and career support activities. Research outcomes and activities of the CAROLINE Fellows will benefit Europe, given the significance of the theme to Europe 2020, e.g. in - employment, climate change and energy, education, and poverty reduction. CAROLINE will deliver experienced researchers with enhanced skills in inter-sectoral and interdisciplinary research and better access to a wider set of future career - opportunities. The IRC has built an impressive array of support for this proposal from stakeholders in Ireland, Europe and internationally, including research performing-organisations, NGOs, IOs and other partners. - - 2021-06-01, ongoing project - - - 2016-06-02 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2015-FP - Marie Skłodowska-Curie Co-funding of regional, national and international programmes (COFUND-FP) - - - MSCA-COFUND-FP - Fellowship programmes - - - Ireland - - - CAROLINE - - - H2020-MSCA-COFUND-2015 - - - 713279 - - - - - European Respiratory Society - - - EUR 1 132 800 - - - REspiratory Science Promoted by International Research Exchanges 3 - - - EUR 2 265 600 - - - Switzerland - - - Other - - The European Respiratory Society (ERS) is the main scientific society in the respiratory field in Europe. ERS mission is to promote lung health and to drive globally standards for respiratory medicine. ERS aims at consistently - achieving its core mission by supporting the forefront of basic and translational research. Since 1997, ERS has operated a successful programme of international exchange of researchers in respiratory science. Under the FP7 COFUND scheme, ERS launched - RESPIRE 1 and RESPIRE 2 fellowship programmes. Here, ERS proposes RESPIRE 3, a new fellowship programme that capitalises on the success of the previous programmes and presents innovative features, taking into consideration the results of the - independent evaluation of the RESPIRE 2 programme. First, RESPIRE 3 funds both European and global fellowships, expanding the international dimension to Third Countries. Second, RESPIRE 3 places major attention to inter-sectoral exposure: fellows - have the possibility to undertake a secondment to industry, fully funded by the programme. Third, RESPIRE 3 complements the host institutions’ programme by proposing training activities aimed at strengthening the professional development of the - fellows. Fourth, RESPIRE 3 sets the frame for the establishment of international contacts by offering dedicated networking opportunities, namely during the annual ERS congress. Fifth, with an increased living allowance and by introducing a family - allowance, RESPIRE 3 provides competitive working conditions to attract the best talents and guarantee them a right balance between career ambitions and personal development. Therefore, the proposed RESPIRE 3 programme, by training post-doctoral - fellows in Europe and globally, will enhance research in the respiratory field, increase the human resources potential in Europe, and contribute to the overall objective and impact of COFUND. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2015-FP - Marie Skłodowska-Curie Co-funding of regional, national and international programmes (COFUND-FP) - - - MSCA-COFUND-FP - Fellowship programmes - - - Switzerland - - - RESPIRE 3 - - - H2020-MSCA-COFUND-2015 - - - 713406 - - - - - TECHNISCHE UNIVERSITEIT DELFT - - - EUR 6 372 000 - - - LEaDing Fellows - - - EUR 12 744 000 - - - Netherlands - - - Higher or Secondary Education Establishments - - The LEaDing Fellow Programme offers 90 two-year postdoc positions to ambitious and excellent researchers who want to perform research in a challenging, internationally esteemed and multidisciplinary environment. The aim is to - help them to develop new research skills and a view on career options in academic research or in an industrial or public setting. The programme is a joint initiative of Delft University of Technology (TU Delft), the beneficiary, and the partners - Leiden University (LEI), Erasmus University Rotterdam (EUR), Erasmus University Medical Centre (Erasmus MC) and Leiden University Medical Centre (LUMC). - - - 2022-01-01, ongoing project - - - 2017-01-02 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2015-FP - Marie Skłodowska-Curie Co-funding of regional, national and international programmes (COFUND-FP) - - - MSCA-COFUND-FP - Fellowship programmes - - - Netherlands - - - LEaDing Fellows - - - H2020-MSCA-COFUND-2015 - - - 707404 - - - - - UNIVERSITEIT LEIDEN - - - EUR 165 598,80 - - - Evolution of sexual dimorphisms: all about losing not choosing? - - - EUR 165 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Males and females often differ dramatically in phenotype, with one sex exhibiting elaborate ornaments absent in the other. Darwin suggested such dimorphism evolves through sexual selection on males to attract females and repel - rival males. Ever since, this framework served to explain why males are showy and females drab. Song in songbirds was a classic example (males sing and females are silent) until our recent research showed that female song is phylogenetically - widespread and probably ancestral. Thus, current sex differences in song must have at least partly resulted from females evolving away from males by losing song. Therefore, the key question is not what has led to elaboration in males, but rather, - what is responsible for losses in females. I will engage a network of experts from three EU institutions and the general public to participate in addressing this new, pertinent question of trait loss in a large-scale phylogenetic analysis across - songbirds. I will focus on three goals important to progress in this field: (1) develop an urgently needed single quantitative score to compare song structure among species, (2) determine how gains and losses of song structure in each sex contribute - to overall dimorphism, (3) compare dimorphism to a broad range of ecological and natural history correlates. From the host and partners, I will receive expert training through research in animal communication, bioacoustics, and character evolution, - including advanced sound analysis tools during a Secondment and leadership training through a major citizen science project with xeno-canto, the world’s largest bird song database. This inclusive mentorship and training will equip me with diversified - and advanced skills to contribute to this important research question and embark on my career goals of leading an independent, integrated research programme in behavioural ecology and evolution. - - 2018-08-31, Grant Agreement terminated | - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - YnotSing - - - H2020-MSCA-IF-2015 - - - 703999 - - - - - Enterprise Ireland - - - EUR 5 310 000 - - - Career Development Fellowships in the National Technology Centre Programme - - - EUR 10 620 000 - - - Ireland - - - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - Career-FIT is a new trans-national scheme that offers an opportunity for experienced researchers to develop their careers n market focused applied research in Ireland's Technology Centres. Covering a wide range of academic and - industry areas aligned with Ireland's Smart Specialisation Strategy, the 15 Centres were established to encourage greater efficiency in the interaction between researchers, industry, and the public sector, in research that promotes economic growth by - its direct relevance to industry agendas. Each multidisciplinary Centre offers excellent facilities and equipment for Fellow use: experienced scientific staff to support the Fellow’s research, and extensive enterprise relationships on which market - focused applied research can be progressed. Following two widely publicised calls that seek to attract the highest quality researchers with their own research proposals, the Career-FIT programme offers 50 fellowships of 36 months’ duration for - incoming mobility to the Centre Hosts, with an enterprise secondment option during the Fellowship. Selection is through a transparent process based on demonstrated excellence of the applicant, potential of the research programme, host organisation - capacity to provide a developmental environment, and training/career development impact of the Fellowship. Fellows are mentored by an experienced Centre mentor(s) concerned not just for their scientific progress but also their training and - development in line with agreed career goals. They will also have support from a Professional Development Advisor and will further benefit from participation in a structured development training programme that targets enhancement of personal - effectiveness as well as competencies relating to innovation management. As a new programme offering interdisciplinary, intersectoral and international features, the Career-FIT human resource development objectives will guarantee the development of - future research and innovation leaders. - - 2021-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2015-FP - Marie Skłodowska-Curie Co-funding of regional, national and international programmes (COFUND-FP) - - - MSCA-COFUND-FP - Fellowship programmes - - - Ireland - - - Career-FIT - - - H2020-MSCA-COFUND-2015 - - - 713654 - - - - - ASTON UNIVERSITY - - - EUR 3 186 000 - - - International Mobility and Training in Photonics Programme - - - EUR 6 372 000 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The aims of the proposed International Mobility and Training in Photonics programme, MULTIPLY, are to facilitate worldwide mobility and offer high-level interdisciplinary and transdisciplinary training for approximately 55 - outstanding international researchers (90 fellow*years) commencing their professional development in the area of photonics science, technology and applications. Applicants from any part of the world will be able to participate in this Programme, - freely choosing their destinations and research topics. Eligible researchers may apply for one of the following mobility elements: a) incoming to Europe, including Europe-to-Europe mobility; b) outgoing from Europe with re-integration. - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2015-FP - Marie Skłodowska-Curie Co-funding of regional, national and international programmes (COFUND-FP) - - - MSCA-COFUND-FP - Fellowship programmes - - - United Kingdom - - - MULTIPLY - - - H2020-MSCA-COFUND-2015 - - - 713694 - - - - - UNIVERSITE DE STRASBOURG - - - EUR 185 076 - - - Luminescent Polymer Nanoparticles with Aza-BODIPYs, Porphyrins and their Metal Complexes for FRET Mediated Ratiometric Oxygen Sensing - - - EUR 185 076 - - - France - - - Higher or Secondary Education Establishments - - This proposed Fellowship brings together an Experienced Researcher from India with expertise in the synthesis of photosensitizers and their photophysical characterization, tuning the excited-state properties, investigation of - their photophysics and photobiology with an internationally recognized Host Laboratory in France with expertise in designing fluorescent molecular and nanoparticle probes for bioimaging. This project will provide (i) interdisciplinary training of - highest quality to become an outstanding scientist with excellent publication record; (ii) enhance European excellence in organic synthesis, nanosciences and biophotonics. The aim of the research project is to obtain ratiometric probes for molecular - oxygen based on biodegradable polymeric nanoparticles (NPs) bearing far-red/near-infrared absorbing triplet sensitizers such as aza-BODIPYs, porphyrins and corresponding metal complexes. The project involves the synthesis of phosphorescent dyes - (aza-BODIPY/porphyrins) and formulation of polymeric NPs encapsulating these dyes. The development of ultra-bright polymer nanoparticles, an innovative method recently discovered in the Host Laboratory, will enable the development of novel dual - emissive polymeric NPs with the triplet sensitizers. In our design, fluorescent NPs excite triplet sensitizers through energy transfer (FRET), resulting in dual emission: fluorescence of NPs and phosphoresce of the sensitizer. Only phosphorescence of - FRET acceptor is sensitive to molecular oxygen (3O2), which provides the mechanism of dual colour ratiometric response to oxygen. The approach will be further validated in solutions and in living cells. The obtained nanoprobes for oxygen will be - applied to living cell and (in collaboration) to whole animals. It is our strong conviction that the possibilities of this multidisciplinary chemistry are enormous, and the end result will be the development of a simple nano-device for molecular - oxygen build from biodegradable materials. - - 2019-05-14, ongoing project - - - 2017-05-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - NanoOxySens - - - H2020-MSCA-IF-2015 - - - 705826 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - - - EUR 318 600 - - - Trinity Long Room Hub Visiting Research Fellows COFUND programme - - - EUR 637 200 - - - Ireland - - - Higher or Secondary Education Establishments - - The Trinity Long Room Hub Visiting Research Fellows Programme will offer opportunities to nine Experienced Researchers from across the spectrum of the Arts and Humanities to spend a fellowship of 12 months duration at Trinity - Colleges’ Arts and Humanities Research Institute. This fellowship programme represents a significant enhancement of the offering of the existing fellowship programme operating in the TLRH. The objectives of the programme are to attract high quality - international researchers from Europe and all over the world via more attractive employment conditions including an employment contract and via wide and rigorous promotion of the calls while open. The programme will provide fellows with training and - networking opportunities that will enhance their career development potential ( via their involvement in the activities of an Interdisciplinary College Research Theme affiliated to the Long Room Hub under which they will be recruited and access to a - range of non research related training opportunities via different units in TCD); to identify the relevance of their work for other sectors outside academia including the public ( via the inclusion of a secondment element in the programme and via - participation in the public engagement activities of the Long Room Hub) and to provide them with interdisciplinary research opportunities( again via involvement in and exposure to staff active in the Interdisciplinary Research Theme under which they - have been recruited). The Interdisciplinary Research Themes involve staff across a TCD schools not only thoseaffiliated to the TLRH (i.e. Computer Science and Statistics, Engineering, Nursing, Social Work and Psychology) that will hopefully stand - them in good stead as they seek to expand their academic networks. Finally Trinity College and the Long Room Hub will support the selection of researchers following an open, merit-based and impartial and equitable selection procedure, based on - international peer review. - - 2020-10-31, ongoing project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2015-FP - Marie Skłodowska-Curie Co-funding of regional, national and international programmes (COFUND-FP) - - - MSCA-COFUND-FP - Fellowship programmes - - - Ireland - - - TLRH-VRF COFUND - - - H2020-MSCA-COFUND-2015 - - - 713730 - - - - - DANMARKS TEKNISKE UNIVERSITET - - - EUR 4 460 400 - - - H.C. Ørsted Fellows Programme – co-funded by Marie Skłodowska Curie Actions (COFUNDfellowsDTU) - - - EUR 8 920 800 - - - Denmark - - - Higher or Secondary Education Establishments - - With the H.C. Ørsted Fellows Programme – co-funded by Marie Skłodowska Curie Actions (COFUNDfellowsDTU) DTU will attract highly talented young researchers through incoming mobility from around the world. The Programme takes - place at the Technical University of Denmark (DTU) which is a top ranked university with focus on all Engineering Sciences as well as Life Science and Biotechnology. - - 2021-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2015-FP - Marie Skłodowska-Curie Co-funding of regional, national and international programmes (COFUND-FP) - - - MSCA-COFUND-FP - Fellowship programmes - - - Denmark - - - COFUNDfellowsDTU - - - H2020-MSCA-COFUND-2015 - - - 713683 - - - - - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - - - EUR 3 398 400 - - - Experienced Researchers Incoming Fellowship Programme at the Ecole Polytechnique Fédérale de Lausanne - - - EUR 6 796 800 - - - Switzerland - - - Higher or Secondary Education Establishments - - EPFL Fellows aims to attract experienced researchers of any nationality to EPFL - one of the leading European institutions of science and technology - to provide them with state-of-the art conditions for research in a - top-class academic environment, to develop their leadership potential and to position them for success as future research leaders through an intensive training. EPFL Fellows is a relatively new programme; it started in 2013 with the support of the EU - MCA-COFUND (FP7). Fellowships may be requested in any scientific discipline and run for a period of 24 months. - - - 2020-06-30, ongoing project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2014-FP - Marie Skłodowska-Curie Co-funding of regional, national and international programmes (COFUND-FP) - - - MSCA-COFUND-FP - Fellowship programmes - - - Switzerland - - - EPFL Fellows - - - H2020-MSCA-COFUND-2014 - - - 665667 - - - - - UNIVERSIDADE DE COIMBRA - - - EUR 148 635,60 - - - Brain stimulation of attention networks: examining old principles and developing new clinical applications - - - EUR 148 635,60 - - - Portugal - - - Higher or Secondary Education Establishments - - Attentional deficits are a frequent consequence of brain damage after stroke. Current treatment approaches using brain stimulation techniques such as transcranial magnetic stimulation (TMS) are based on two theoretical - constructs, namely (1) inter-hemispheric inhibition within the dorsal attention network and (2) the presence of interactions between the ventral and dorsal attention network and. The proposed projects put these constructs to the test by combining TMS - with neuroimaging and, based on these findings, explore novel brain connectivity based TMS treatments. Collectively, these projects advance current neurocognitive models of attentional control and lead to advanced TMS protocols that can alleviate - attention deficits in patients. - - 2018-05-31, ongoing project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Portugal - - - TMS_ATT - - - H2020-MSCA-IF-2015 - - - 708492 - - - - - UNIVERSIDADE DE LISBOA - UNIVERSIDADE DE COIMBRA - CAMARA MUNICIPAL DE LISBOA - - - EUR 122 050 - - - CITIZEN SCIENCE: BRIDGING THE GAP BETWEEN RESEARCH AND SOCIETY IN PORTUGAL - - - EUR 122 050 - - - Portugal - Portugal - Portugal - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - The active participation of citizens in science related issues has significantly increased in the past decades and citizen science is top-priority in many institutions and governments across Europe. Portugal, however, is still - lagging a little behind. This proposal for the European Researcher’s Night 2014 and 2015 in Portugal – CITSCI – has two broad aims. - - - 2015-11-30, closed project - - - 2014-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.5."> - - - MSCA-NIGHT-2014 - European Researchers' Night (NIGHT) - - - CSA - Coordination and support action - - - Portugal - - - CITSCI - - - H2020-MSCA-NIGHT-2014 - - - 633379 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 185 076 - - - Doping Colloidal Nanoplatelets: Synthesis, Self-assembly and Spectroscopy - - - EUR 185 076 - - - France - - - Research Organisations - - Two dimensional (2D) nanomaterials have attracted rising scrutiny from the research community in the last decade due to their outstanding physical, optical and structural properties. Beyond the well-known example of graphene - and other exfoliated bulk materials, a new colloidal route has recently emerged towards such materials and offers a high degree of control on the structure of these nanosheets. Among these, atomically flat, quasi-two dimensional, colloidal - semiconducting (CdS, CdSe and CdTe) nanoplatelets (NPLs) have very interesting opto-electronic properties. Our goal is to fully exploit the potential of these NPLs by doping them with transition metal ions (Mn2+, Cu2+ or Ag+). With the help of doping - in such small systems, we can tune the absorbance, photoluminescence, carrier density and mobility of these materials and extend the potential of these materials for various applications such as field effect transistor, light emitting devices or - photovoltaic solar cells. We will devise new synthetic strategies towards doped semiconducting NPLs and characterize their structural and optical and electronic properties using state of the art techniques. Advanced structural characterization (XRD, - TEM, STEM) will be coupled to optical spectroscopy (fluorescence lifetimes, absorption, emission and excitation spectra) both in solution and on single objects. Afterwards, we will assemble these thin doped platelets together to form supraparticles - and large-scale assemblies using different soft-matter techniques (depletion interaction, polymer grafting, templating by an interface) in order to tune their optoelectronic properties. A fine control of the assembly process would direct to new - fundamental collective effects and easy processing and orientation of doped platelets, which is a prerequisite for their use in applications. - - 2018-01-10, closed project - - - 2016-01-11 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - DECAGON - - - H2020-MSCA-IF-2014 - - - 661199 - - - - - ACADEMISCH ZIEKENHUIS GRONINGEN - - - EUR 1 674 240 - - - Protecting patients with enhanced susceptibility to infections - - - EUR 3 348 480 - - - Netherlands - - - Higher or Secondary Education Establishments - - The Microbes in Health and Disease research programme at the University Medical Center Groningen (UMCG) proposes the Doctoral Training Programme PRONKJEWAIL (‘a real gem’) in the field of hospital care and infection. The - specific training objective is ‘protecting patients with enhanced susceptibility to infections’. PRONKJEWAIL will recruit 16 international ESRs, who will be trained in research, transferable skills, and network and capacity building. They will be - guided by experienced supervisors from the departments of Medical Microbiology, Internal Medicine, Intensive Care, Clinical Pharmacy and Pharmacology, Rheumatology and Immunology, Surgery, Cell Biology, and Pharmacoepidemiology and Pharmacoeconomics - at the UMCG. - - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2015-DP - Marie Skłodowska-Curie Co-funding of regional, national and international programmes (COFUND-DP) - - - MSCA-COFUND-DP - Doctoral programmes - - - Netherlands - - - PRONKJEWAIL - - - H2020-MSCA-COFUND-2015 - - - 713660 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 158 121,60 - - - Archaeology, Landscapes and Heritage in the Iberian Southeast - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - This training-through-research project at the Institute of Heritage Sciences of the Spanish National Research Council (Incipit-CSIC), aims both to generate new scientific knowledge on the archaeology of the landscapes and the - socio-political processes of the Final Iron Age and the Early Roman period, and to enhance their value for cultural heritage management and development in Murcia, in the Spanish Southeast. In this sense, this proposal aims to create a fruitful link - between the applicant’s historical and archaeological research background and skills and the opportunities to learn and to develop a heritage outreach project. The interest of the project is due to both, the lack of landscapes studies which focus on - the Iron Age in this region from a diachronical and landscape perspective, and the remarkable socio-political transformations undergone by the local communities in the period between the 5th and the 1st centuries BC. The landscape will be here - understood like expression of the social and political interactions, but also like a space with an active role in their development, at different levels. All the evidences will be compiled, for the first time, through an interdisciplinary methodology - (archaeological record, ancient texts, paleoenvironmental data, integration in a GIS, etc.) and will be analysed from a contextualized and comparative European perspective, which the regional research in this period lacks. Results will be - disseminated by means of several impact publications but also beyond the strictly scientific environment, with the support of the host centre, the regional museums and other institutions. Regarding the heritage perspective this project aims to allow - the applicant to learn how to re-direct all this knowledge towards a proper and effective management and communication of the important and rather unknown heritage value of those sites. - - 2017-05-31, closed project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - ALHIS - - - H2020-MSCA-IF-2014 - - - 654906 - - - - - UNIVERSITAET BREMEN - - - EUR 1 831 200 - - - Bremen International Graduate School of Social Sciences - Doctoral Education in Partnerships - - - EUR 3 662 400 - - - Germany - - - Higher or Secondary Education Establishments - - BIGSSS-departs (BIGSSS Doctoral Education in Partnerships) offers doctoral studies in a program that combines close supervision of dissertation work with demand-tailored education, both embedded in a vibrant research landscape - at the Bremen International Graduate School of Social Sciences (BIGSSS). The core disciplines comprise political science, sociology, and psychology. Program participants will follow a 42 months structured curriculum including a stay abroad at an - external academic partner institution or with an external non-academic partner. BIGSSS has gathered a network of some of the most prestigious international social science partner organizations. With features such as Career day or the Research day, a - strong inter-sectorial exposure both in the partner network and with regards to the composition of the curriculum is an essentially new feature of BIGSSS-departs. Through a secure employment contract, the monthly pay in BIGSSS-departs will include - health insurance and all German social security benefits already. Even though BIGSSS-departs is connected to a sole beneficiary (University of Bremen), it uses structures and resources of two universities. - - 2021-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2015-DP - Marie Skłodowska-Curie Co-funding of regional, national and international programmes (COFUND-DP) - - - MSCA-COFUND-DP - Doctoral programmes - - - Germany - - - BIGSSS-departs - - - H2020-MSCA-COFUND-2015 - - - 713639 - - - - - DWI LEIBNIZ-INSTITUT FUR INTERAKTIVE MATERIALIEN EV - STICHTING KATHOLIEKE UNIVERSITEIT - UNIVERSIDAD DE VALLADOLID - AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH - ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS - NovioSense BV - PEPSCAN THERAPEUTICS BV - LIFETEC GROUP BV - TECHNICAL PROTEINS NANOBIOTECHNOLOGY SL - - - EUR 3 523 738,32 - - - Engineering responsive and biomimetic hydrogels for biomedical therapeutic and diagnostic applications - - - EUR 3 523 738,32 - - - Germany - Netherlands - Spain - Austria - Greece - Netherlands - Netherlands - Netherlands - Spain - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - BIOGEL is set up to educate young scientists to develop innovative hydrogel chemistries and systems for biomedical applications. The first objective is to provide a platform for young researchers to undergo a well-rounded PhD - education, particularly focussed on translational skills for a career focused in biomedical research and medical technology development. The second objective is to engineer functional and responsive hydrogels, which resemble specific properties of - the extracellular matrix. The third objective is (i) to enhance the efficacy of medical devices by 2D biointegrative coatings that direct and orchestrate the interface to living cells and tissue and enable improved integration within the body, (ii) - to advance therapeutic measures by 3D templates for tissue repair, and (iii) to enable new diagnostic tools by responsive diagnostic hydrogels. BIOGEL follows an international, interdisciplinary, and intersectoral approach organized in 9 and 8 - interwoven work and training packages respectively. - - - 2018-12-31, ongoing project | - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - BIOGEL - - - H2020-MSCA-ITN-2014 - - - 642687 - - - - - UNIVERSITY COLLEGE LONDON - MEDICAL RESEARCH COUNCIL - - - EUR 195 454,80 - - - Computation of innate threats and defensive behaviour in the mouse - - - EUR 195 454,80 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Research Organisations - - Innate defensive behaviours are emergency responses that animals use to avoid predators and environmental threats, such as escape to a safe shelter or freezing to avoid detection. Engaging in defensive behaviour at the right - time and choosing the correct response is essential for survival, but little is known about how the brain achieves this. In this project we aim to understand the neural circuits that process sensory information to compute the presence of a threat and - the most appropriate defensive action. We will focus on the mouse superior colliculus (SC), an evolutionarily conserved brain region thought to be crucial for defensive behaviours. - - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - defence_SC - - - H2020-MSCA-IF-2015 - - - 706136 - - - - - EUROPEAN MOLECULAR BIOLOGY LABORATORY - - - EUR 6 372 000 - - - EMBL Interdisciplinary, International and Intersectorial Postdocs - - - EUR 12 744 000 - - - Germany - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The EIPOD programme was developed in 2007 with the objective of making use of the excellent scientific environment available at EMBL to support an innovative fellowship programme focused on interdisciplinary research training - for postdoctoral fellows. EI3POD is designed to enrich and significantly build upon the very successful EIPOD programme and bears a significant number of novel features for scientific collaboration as well as vocational skills training and career - development. - - - 2020-11-30, ongoing project - - - 2015-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2014-FP - Marie Skłodowska-Curie Co-funding of regional, national and international programmes (COFUND-FP) - - - MSCA-COFUND-FP - Fellowship programmes - - - Germany - - - EI3POD - - - H2020-MSCA-COFUND-2014 - - - 664726 - - - - - RIJKSUNIVERSITEIT GRONINGEN - - - EUR 1 988 160 - - - Local Training Network on Novel Tailor-Made Antimicrobials and Delivery Strategies From Synthesis towards Clinical Applications - - - EUR 3 976 320 - - - Netherlands - - - Higher or Secondary Education Establishments - - The current overuse of antibiotics is leading to the emergence of multidrug resistant (MDR) bacteria. These MDR pathogens continue to evolve at a terrifying rate and confer resistance to most or all presently available - antibacterial treatments. Antimicrobial resistance is an eminent global problem that calls for an integrated approach that surpasses national borders, sectors, and disciplines. The COFUND ALERT programme addresses this call by establishing a - dedicated doctoral training programme with an international, interdisciplinary and inter-sectoral focus. Nineteen excellent Early Stage Researchers (ESRs) will be employed at the University of Groningen (RUG). ALERT is based at RUG but is tightly - connected with multiple international academic and private partner organisations, each providing complementary research or training. ALERT aims to develop the best practices in high quality training and research. ALERT achieves this through advanced - multidisciplinary research training extended with development of dedicated transferable and entrepreneurial skills. ESRs will develop novel antimicrobial drug candidates through chemical, biotechnological and nanotechnological synthesis and - subsequent in vivo testing. All ALERT Principal Investigators have ample experience with supervising PhD students, which ensures an attractive and vibrant research environment for the ESRs. In addition, access to excellent modern research facilities - is guaranteed. Thus, the ALERT programme creates an optimal research and training environment that is far greater than the sum of its individual parts. ALERT’s long-term ambitions are to establish a strong and coherent international network that - links together highly skilled young researchers as well as established scientists, who far beyond the funding period will continue to inspire each other to excel in antimicrobial resistance research in order to tackle the antimicrobial challenge. - - 2021-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2015-DP - Marie Skłodowska-Curie Co-funding of regional, national and international programmes (COFUND-DP) - - - MSCA-COFUND-DP - Doctoral programmes - - - Netherlands - - - ALERT - - - H2020-MSCA-COFUND-2015 - - - 713482 - - - - - UNIVERSITA DEGLI STUDI DI TERAMO - - - EUR 941 760 - - - Food quality and food innovative strategies to prevent reproductive and eating disorders - - - EUR 1 883 520 - - - Italy - - - Higher or Secondary Education Establishments - - The main objective of REP-EAT is to build up a new and innovative research and training doctoral programme (DP) in the interdisciplinary domain of food and healthy diet to deepen the impact of food quality on reproductive - Health (REP) and eating disorders (EAT). In compliance with the concept of “One Health”, REP-EAT DP will focus on the effect of diet determinants on both humans and animals thus implying a strict integration amongst food and life science research - advances. - - 2021-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2015-DP - Marie Skłodowska-Curie Co-funding of regional, national and international programmes (COFUND-DP) - - - MSCA-COFUND-DP - Doctoral programmes - - - Italy - - - REP-EAT - - - H2020-MSCA-COFUND-2015 - - - 713714 - - - - - ITA-SUOMEN YLIOPISTO - - - EUR 1 569 600 - - - Biomedical Engineering and Medical Physics - - - EUR 3 139 200 - - - Finland - - - Higher or Secondary Education Establishments - - The BioMEP brings together complementary expertise of 8 leading research groups in Biomedical Engineering (BM) and Medical Physics (MP) across Europe to offer unique inter-disciplinary and intersectorial research and training - opportunities for Early-Stage Researchers (ESRs). BioMEP aims to fulfill the demand for highly-qualified BM and MP addressing the needs of the academic, healthcare and industry sector, and thus to fully prepare them to meet the increasing demands of - the European labor market. The specific objectives of BioMEP are: to attract highly-qualified international ESRs and offer them excellent expertise in diverse areas of BM and MP research and thus stimulate successful careers both in academia and - beyond; to promote excellence in BM and MP research area; to foster long-term collaboration at the European level; to strengthen the international dimension of BioMEP. BioMEP is structured around five interrelated focus research areas: - Musculoskeletal biomechanics, Molecular, cell and tissue engineering, Biosignals, Multimodal neuroimaging, Biomedical devices and diagnostics combined with specific research and training, internet-based training, regular seminars and summer schools. - BioMEP intends to attract highly-qualified ESRs, through of a widely disseminated call for proposals, a merit-based selection process founded on international peer-review, appealing working conditions, research skills and courses specific to the area - (e.g. Biomedical signal analysis, Biomechanics) and complementary training skills (e.g.entrepreneurship, ethics) to support ESRs career development. BioMEP will widen the career perspectives of ESRs by enhancing their professional experiences through - the inclusion of secondments in private companies and hospitals. Thus, BioMEP will increase the national and as well European competitiveness by providing a new generation of highly-qualified experts in BM and MP able to translate basic science - research results into healthcare solutions. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2015-DP - Marie Skłodowska-Curie Co-funding of regional, national and international programmes (COFUND-DP) - - - MSCA-COFUND-DP - Doctoral programmes - - - Finland - - - BioMEP - - - H2020-MSCA-COFUND-2015 - - - 713645 - - - - - OULUN YLIOPISTO - - - EUR 2 092 800 - - - Novel Imaging and Characterisation Methods in Bio, Medical, and Environmental Research and Technology Innovations - - - EUR 4 185 600 - - - Finland - - - Higher or Secondary Education Establishments - - The I4Future Programme is a novel international, interdisciplinary and inter-sectoral doctoral programme hosted at the University of Oulu. The programme is based on full exploitation of the possibilities of modern imaging and - characterisation methods in cross-disciplinary work. The unique training programme aims to respond to the increasing need for skilled next-generation ESRs in the changing and demanding European job markets in industry, the public sector and academia. - I4Future brings together the complementary and supplementary expertise of world-class researchers in training ESRs with interdisciplinary visions in highly relevant socio-economic research areas and state-of-the-art techniques. I4Future combines five - faculties and 17 research groups of UOULU, driven together with eight international universities and nine private companies from the paper, steel, mining and medical industries as well as appliances manufacturing and four multidisciplinary public - sector organisations. The I4Future programme will provide 20 ESRs with a first-hand understanding of how research develops from basic science findings to interdisciplinary innovations and commercially valuable applications. The programme exploits - local, national and international strengths of the network partners at multiple levels: excellence in research, local and European cutting-edge infrastructures, collaboration networks and secondments, and wide dissemination and outreach. I4Future - builds upon a critical mass of interdisciplinary, inter-sectoral and international expertise and provides a unique combination of complementary methodological approaches for high-quality training that would not be possible to implement at any site or - organisation alone. - - 2021-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2015-DP - Marie Skłodowska-Curie Co-funding of regional, national and international programmes (COFUND-DP) - - - MSCA-COFUND-DP - Doctoral programmes - - - Finland - - - I4FUTURE - - - H2020-MSCA-COFUND-2015 - - - 713606 - - - - - UNIVERSITE D'AIX MARSEILLE - - - EUR 2 354 400 - - - International, inter-sectoral and inter-disciplinary Doctoral Training Programme to Aix-Marseille University - - - EUR 4 708 800 - - - France - - - Higher or Secondary Education Establishments - - DOC2AMU raised out of the willpower of the Provence Alpes Cote d’Azur key regional actors in Research and Innovation to offer to the most promising early stage researchers an international, inter-sectoral and - inter-disciplinary innovative doctoral training programme. The excellence is ensured not only by the research ecosystem of Aix-Marseille University but also through the open, transparent, merit-based, impartial and equitable selection process set up - to assess the perfect match between the proposed doctoral projects and the ESRs. Further to ensure the best career perspectives after ESR’s’ graduation, DOC2AMU set up an original training programme offering a training scheme combining options of the - 3 international/inter-sectoral and interdisciplinary dimensions, including a comprehensive package of transferable skills training, along with a specific mentoring scheme involving an academic Supervisor, a non-academic and/or international tutor(s) - and a Scientific & Training Supervisory Committee. Apart from the recruitment of 30 ESRs, it is expected that DOC2AMU will enhance skills of AMU ESRs including transferrable ones; upgrade AMU doctorate’s curriculum, by generalizing the innovative - Doctorate Principles as a standard for all Doctoral training in AMU; reinforce AMU capacities to host talented international researchers in high standard working and improved employment conditions; intensify the cooperation and the alignment of AMU - Human Resources practices between key regional academic and non-academic research and innovation players; develop new synergies on the regional territory; strengthen the innovative aspects of the Regional Doctoral programme and disseminating HR and - training good practices in other Universities and Research organisations in PACA; and prioritize research projects focusing on the regional Research and Innovation Strategies for Smart Specialization strategies to create a regional leverage in terms - of knowledge and innovation. - - 2021-11-30, ongoing project - - - 2016-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2015-DP - Marie Skłodowska-Curie Co-funding of regional, national and international programmes (COFUND-DP) - - - MSCA-COFUND-DP - Doctoral programmes - - - France - - - DOC2AMU - - - H2020-MSCA-COFUND-2015 - - - 713750 - - - - - THE UNIVERSITY OF NOTTINGHAM - - - EUR 1 883 520 - - - The Integration of Novel Aerospace Technologies - - - EUR 3 767 040 - - - United Kingdom - - - Higher or Secondary Education Establishments - - INNOVATIVE will enable the systematic integration of novel aerospace technologies through the training of 24 researchers through a comprehensive multidisciplinary programme. - - - 2021-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2014-DP - Marie Skłodowska-Curie Co-funding of regional, national and international programmes (COFUND-DP) - - - MSCA-COFUND-DP - Doctoral programmes - - - United Kingdom - - - INNOVATIVE - - - H2020-MSCA-COFUND-2014 - - - 665468 - - - - - NARODOWE CENTRUM NAUKI - - - EUR 5 841 000 - - - SUPPORTING MOBILITY IN THE ERA THROUGH AN INTERNATIONAL FELLOWSHIP PROGRAMME FOR DEVELOPEMENT OF BASIC RESEARCH IN POLAND - - - EUR 11 682 000 - - - Poland - - - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - POLONEZ is a Fellowship Programme supporting international incoming researchers working in the broad field of research regardless of their nationality. It will be implemented by the National Science Centre (NCN), a government - agency funding basic research in Poland. The NCN has already designed 11 funding schemes supporting researchers on every stage of their research career and regularly announces calls for proposals. The Centre is also involved in international funding - initiatives, e.g. ERA-nets, JPIs. It follows a strictly bottom-up approach, allowing researchers to freely choose their research topic and host institution. POLONEZ, planned for 60 months, enables the NCN to implement 3 calls for proposals in order - to select 90 fellows. It is targeted at experienced researchers who may apply for 12-24-month-fellowships in host institutions in Poland, both academic and non-academic, public or private. Apart from living, mobility and family allowances, they are - offered a research grant which amounts to ca. € 4 200 per month, to cover the costs of a research project in a discipline freely chosen by the applicant. The fellows are also given an opportunity to participate in a variety of research and - non-research trainings provided by the NCN and the host institution. One of the main goals of POLONEZ is to enhance incoming mobility in Poland. Although Polish host institutions offer an attractive research setting and high quality resources, - fellowships in Poland attract fewer researchers. Also, many Polish researchers still seek temporary and permanent positions outside of Poland and Europe. Therefore, in order to counteract “brain drain,” build up a positive image of Polish research - institutions and encourage foreign researchers to develop their careers in Poland, we offer them the opportunity to collaborate with the best Polish research organisations. POLONEZ thus paves the way for stronger international mobility in research - and the integration of research communities. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2014-FP - Marie Skłodowska-Curie Co-funding of regional, national and international programmes (COFUND-FP) - - - MSCA-COFUND-FP - Fellowship programmes - - - Poland - - - POLONEZ - - - H2020-MSCA-COFUND-2014 - - - 665778 - - - - - INSTITUT CURIE - - - EUR 2 746 800 - - - Institut Curie 3-i PhD Program - - - EUR 5 493 600 - - - France - - - Research Organisations - - The new IC-3i-PhD program of Institut Curie and its partners will produce top-level scientific knowledge by promoting basic interdisciplinary research that will be translated into novel therapeutic avenues for diagnosis and - treatment. The completely re-structured, revitalized, and ambitious international “Triple i” PhD program is strengthened by trans- and inter-disciplinary and inter-sectorial research projects and will offer 35 international PhD positions. The program - will teach PhD/Doctoral Program recipients to be excellent researchers of tomorrow; to perform research but also enhance innovation through research via established working relationships with private industry, and by supporting the creation of Small - and Medium-sized Enterprises (SMEs). The objective of the doctoral programme is to offer an international, inter-disciplinary, and inter-sectorial training program for the researchers, including training-through-research (both on site and through - secondments) as well as hands-on training in transferable skills. Furthermore, supporting researchers’ career development via a structured career plan, and a commitment to providing fellows with the transferable skills they need, will change the - standard of excellence for PhDs at the institute, and beyond. Training IC-3i-PhDs to the high standard set out in the program will ultimately lead to producing a new generation of researchers and researcher-physicians working side by side on - improving health outcomes, reducing health inequalities, and promoting active and healthy ageing. Overall the proposed project will further stimulate the development of European research and human resource capacities, knowledge transfer between - academic institutions and industrial stakeholders and thus strengthen the competitiveness and innovation of EU industries. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2014-DP - Marie Skłodowska-Curie Co-funding of regional, national and international programmes (COFUND-DP) - - - MSCA-COFUND-DP - Doctoral programmes - - - France - - - IC-3i-PhD - - - H2020-MSCA-COFUND-2014 - - - 666003 - - - - - ACADEMISCH ZIEKENHUIS GRONINGEN - - - EUR 1 046 400 - - - European Glaucoma Research Training Program - - - EUR 2 092 800 - - - Netherlands - - - Higher or Secondary Education Establishments - - Glaucoma is the most common age-related neurodegenerative eye-disease in western society and one of the four major blinding eye diseases (cataract, macular degeneration, glaucoma, and diabetic retinopathy). Glaucoma is - characterized by a progressive loss of retinal nerve cells. The early changes are often unnoticed by the patient. If untreated or detected too late, glaucoma will end up in blindness, yielding a profound loss of quality of life for the individual and - major costs to society. In Europe, there are approximately 3 million people with glaucoma. They all need chronic medical care and, despite of that, approximately 15% of them will become blind during their lifetime. - - 2020-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2014-DP - Marie Skłodowska-Curie Co-funding of regional, national and international programmes (COFUND-DP) - - - MSCA-COFUND-DP - Doctoral programmes - - - Netherlands - - - EGRET - - - H2020-MSCA-COFUND-2014 - - - 661883 - - - - - EUROPEAN MOLECULAR BIOLOGY LABORATORY - - - EUR 159 460,80 - - - Structural and functional characterization of large viral and human non-coding RNA motifs involved in HIV infection - - - EUR 159 460,80 - - - Germany - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - HIV infections cause 1.2Mi deaths/year worldwide at steadily-increasing rates, partly because of antiretroviral resistance and the impossibility of eradicating latent viruses. To expand our understanding of HIV pathogenesis, - we need to unravel all molecular mechanisms involved in HIV progression. Large viral and human RNAs are emerging as key players in HIV infection. To characterize such RNAs, I will employ an integrated structural biology approach complemented by - biochemical and functional assays in vitro and in vivo and I will address two fundamental questions: - - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - 3DviralRNA - - - H2020-MSCA-IF-2016 - - - 748759 - - - - - UNIVERSITE PARIS DIDEROT - PARIS 7 - - - EUR 4 708 800 - - - INterdiSciPlinarity and excellence for doctoral training of International REsearchers in Paris - - - EUR 9 417 600 - - - France - - - Higher or Secondary Education Establishments - - United in a Community of Universities and Institutions, called “Université Sorbonne Paris Cité” (USPC), eight research universities and five research organisations located in Paris and its surroundings have decided to join - their forces to build a world-class new type of university. - - 2020-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2014-DP - Marie Skłodowska-Curie Co-funding of regional, national and international programmes (COFUND-DP) - - - MSCA-COFUND-DP - Doctoral programmes - - - France - - - INSPIRE - - - H2020-MSCA-COFUND-2014 - - - 665850 - - - - - FUNDACION AGENCIA ARAGONESA PARA LA INVESTIGACION Y EL DESARROLLO - - - EUR 170 121,60 - - - Beta-lactams for Tuberculosis Treatment - - - EUR 170 121,60 - - - Spain - - - Other - - Tuberculosis (TB) is the most deadly infectious disease worldwide. TB therapy takes 6 months with unpleasant side effects that leads to poor adherence and the development of drug resistance. Patients infected with multi (MDR) - or extensively (XDR) drug resistant strains must undergo longer treatments (up to 24 months) associated with even severe side effects and only 30-50% positive treatment outcomes. New treatments are urgently needed. - - 2020-03-31, Grant Agreement signed - - - 2018-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-SE - Society and Enterprise panel - - - Spain - - - BLMs 4 TB - - - H2020-MSCA-IF-2016 - - - 749058 - - - - - PHOTANOL BV - - - EUR 177 598,80 - - - Realizing a development platform for sustainable sun powered production of intermediates for chemical industry. - - - EUR 177 598,80 - - - Netherlands - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The objective is to develop a base cyanobacterial cell factory for terpene precursors that can be the development platform for commercial terpene production with cyanobacteria. - - 2020-01-01, ongoing project - - - 2018-01-02 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-SE - Society and Enterprise panel - - - Netherlands - - - cTerF - - - H2020-MSCA-IF-2016 - - - 752384 - - - - - UNIVERSITEIT VAN AMSTERDAM - - - EUR 177 598,80 - - - The radius of Generalized Trust among different educational groups: Are those 'most people' out-groups? - - - EUR 177 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - European countries experience an increasing policy concern about migration’s impacts on social cohesion. Social cohesion is understood as ‘solidarity’ and ‘togetherness’, often measured by generalized trust. However, studies - using think aloud data demonstrate that many respondents high in generalized trust think ‘most people’ refers to people they know, whereas a high proportion of those low in trust think about strangers. Thus this project starts by recognizing that - generalized trust is not necessarily the same as lack of prejudiced feelings about out-groups and aims to return to the overlooked basics: the operationalization of generalized trust, which is allegedly in decline by ethnic diversity. Furthermore, - this project aims to relate attitudes to implicit measures and behavior in a controlled setting, which is ignored in previous research. Failure to accurately map the relation between generalized and out-group trust may not only lead us to possibly - overestimate or underestimate their incidence in different settings, but it also conceals clear public policy directions. The first two objective of this research are: to examine the measurement similarity between generalized and out-group trust - among educational groups with the aid of think aloud data and invariance testing. The third objective is to experimentally assess how well these attitudes relate to less socially desirable measures, namely reaction time in associating out-groups and - in-groups with (un)pleasant words and how far research participants choose to sit away from in-groups and out-groups as social distance. Results from this project will benefit governmental agencies and academics seeking to map social cohesion by - providing better quality indicators. Furthermore, the EF will enable the candidate to further develop her position as a leading academic in political psychology. This project, finally, contributes to an overarching policy area of the EU in enhancing - social inclusion and inclusive growth. - - 2020-02-29, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - Trust Radius - - - H2020-MSCA-IF-2016 - - - 750832 - - - - - UNIVERSITY COLLEGE LONDON - - - EUR 183 454,80 - - - Designing Engineers: Harnessing the Power of Design Projects to Spur Cognitive and Epistemological Development of STEM Students - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Germany fell 76,400 engineers short in 2011. Britain falls short 55,000 engineers every year. Such deficits adversely affect Europe’s R&D, patent filings, and tech production. Failure to attract women exacerbates the - crisis. Europe urgently needs diverse engineers who can work collaboratively and creatively. Why does engineering struggle to attract students when architecture courses fill with women and men? Education experts (Boyer and Mitgang) say architects - learn in more hands-on and effective ways than engineers. Which techniques can be transferred to make engineering more compelling? - - 2020-01-14, ongoing project - - - 2018-01-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - DesignEng - - - H2020-MSCA-IF-2016 - - - 747069 - - - - - UNIVERSITY COLLEGE LONDON - - - EUR 183 454,80 - - - Seismic Ambient Noise as a proxy to investigate ICE in polar regions - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Polar regions are some of the least accessible regions on Earth, yet the number of continuously operating seismic stations has increased ten-fold in the last decades. When traveling in presence of ice, the seismic wavefield is - reshaped and thus seismology is an ideal powerful tool to extract and monitor key ice-properties. In particular, the seismic ambient noise (SAN) wavefield is recorded continuously in time, having high temporal resolution. Compared to costly - satellites and airborne campaigns commonly used to study ice in polar regions, seismology can (a) take records further back in time, (b) fill spatial gaps in satellite and airborne data and (c) fill temporal monitoring gaps. However, little is known - about SAN in polar regions and how it can be used to infer ice properties. SAN-ICE will use for the first time a combination of advanced seismic data analysis and full wavefield numerical simulations to (1) characterize seismic wave propagation in - presence of ice (both land and sea ice) and (2) infer ice and uppermost crustal properties using SAN. My work will consist of three work packages. First, by using novel and classical seismic methods, I will obtain high resolution maps across the - whole Greenland and Antarctica of seismic velocity, density and thickness of ice and crust, completely constrained by seismic data alone. Second, I will perform time-dependent analyses of all the seismic data available up to 40 years ago from - Greenland and Antarctica for monitoring ice and crustal structure changes. Third, by modeling the full wavefield and using oceanographic and satellite data, I will investigate the damping effect of sea ice on seismic waves and get new insights on sea - ice changes. With this proposed work, I will explore new routes entirely based on seismology and SAN for helping to quantify ice mass changes over time, which in turn, are crucial for predictions of future sea level rise, one of the most devastating - potential impacts of climate change. - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SAN-ICE - - - H2020-MSCA-IF-2016 - - - 747805 - - - - - POLITECHNIKA POZNANSKA - - - EUR 227 361,60 - - - Sustainability Assessment based on Decision Aiding - - - EUR 227 361,60 - - - Poland - - - Higher or Secondary Education Establishments - - There is a pressing need for clear and understandable information regarding the sustainability of products, companies and policies. To achieve this, one of the main priorities for the European Commission is strengthening the - integration of Sustainable Development (SD) principles into the policy-making processes. For this to occur there is an impelling need for: (i) enhancing the economic profitability of businesses employing the principles of a circular economy; (ii) - providing consumers with a comprehensive understanding of the impacts of products from a sustainability perspective, including environmental (e.g. energy consumption), economic (e.g. raw materials costs) and social considerations (e.g. workers’ - safety); and (iii) accounting for limited availability of primary resources. These objectives can be achieved if robust evaluations for the sustainability of products, companies and policies are conducted and communicated. The premier tool to support - the achievement of these objectives is Sustainability Assessment (SA). Due to the importance of such societal challenges, an increasing number of criteria have been proposed to conduct a SA. A main challenge is the ability to communicate effectively - the sustainability of the target alternatives in an easily understandable format, being as a score of performance, a preference class, or a ranking. Multiple Criteria Decision Aiding (MCDA) is an excellent approach to achieving these goals. - Frameworks applying MCDA to SA have been proposed, but they are tailored to a set of MCDA methods and only support a limited typology of data and preference elicitation techniques. This SAbDA project will tackle these shortcomings by introducing a - step-wise framework to support the development of SAs and selection of the most relevant MCDA method(s). This will include assessing the MCDA methods currently available and developing new ones, including those for evaluations at the micro (product) - and meso (organization, region) levels. - - 2021-09-25, Grant Agreement signed - - - 2018-09-26 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Poland - - - SAbDA - - - H2020-MSCA-IF-2016 - - - 743553 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 173 076 - - - Novel High-Power Single-Frequency Neodymium-Doped Fibre Lasers - - - EUR 173 076 - - - France - - - Research Organisations - - Single-frequency lasers are crucial tools for a variety of applications such as atom cooling, metrology and sensing, among others. However, to date there are still uncovered wavelength domains due to technological challenges, - especially in the 900-940 nm and 455-470 nm windows for applications demanding robust systems. This project mainly focuses on the investigation of novel high-power single-frequency lasers at these wavelengths, in both continuous wave and pulsed - operation. The outstanding features of fibre laser technology make it the best option to surpass the power limitations of other technologies. To date multi-Watt neodymium-doped fibre lasers have only been demonstrated in a longitudinal multimode - operation using resonant cavity configurations. The development of multi-Watt-level single-frequency lasers at 910-940 nm remains a challenge not yet achieved. However, in this project we propose a radical new approach which is based on novel exotic - fibres doped with neodymium in a master-oscillator power amplifier configuration. Using this new approach, the applicant has already demonstrated a single-frequency fibre laser at 922 nm with 1 W output power during a post-doc position at the host - centre. This preliminary results lays a solid foundation for the success of the project. The main goal of the project is to continue pushing beyond the state of the art, developing new, robust high-power lasers in the 910-940 nm wavelength range, and - in the 455-470 nm window by second harmonic generation. The project aims to develop new laser systems for both advanced atomic physics and dermatological applications. This interdisciplinary project will combine the fellow’s expertise in - single-frequency fibre lasers with the world-leading expertise of the host group in high-power low-noise lasers. In addition, the project will benefit from the host’s well-established partnerships with academia and industry actors at the forefront of - photonics in France. - - 2019-04-16, ongoing project - - - 2017-04-17 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - NeoLaS - - - H2020-MSCA-IF-2016 - - - 748839 - - - - - UNIVERSITY COLLEGE LONDON - - - EUR 183 454,80 - - - Urban Landscapes of Power in the Iberian Peninsula from Late Antiquity to the Early Middle Ages - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Architecture as a symbol of power has long been intentionally used to define relationships between individuals, groups, cities and governments. Substantial traces of power and authority in architecture and landscapes during - Late Antiquity also demonstrate the economic and political wellbeing of newly emerging elites in Western Europe. I aim to enhance archaeological knowledge of late antique society by exploring how new topographies of power were configured. The - research involves six case studies in the Iberian Peninsula. To properly integrate them in a wider archaeological context, I will look at other representative sites in England and France. Each town to be studied has substantial archaeological - evidence for the study of spatial configuration of power and to generate urban patterns. Cathedrals, palaces and the construction of large ecclesiastical complexes essentially materialized the spread of early Christianity and the secular elites form - the basis of what I will explore in my project. Developed new archaeologies are starting to offer alternative pictures to the traditional images of townscape revealing diverse modes of material expression, symbolic significances of places, the social - usage of space, and of structural change. The focus of this research is to draw together still scattered data to chart and interpret the changing nature of life in towns through the Late Antiquity period until Early Middle Age (AD 450-800). A - multi-facetted archaeological approach using Geomatic proceedings and its methods and tools (Geography Information Systems, Photogrammetry and Remote Sensing) makes it possible to reconstruct ancient landscapes generated by social actions within - territories across time. A further goal is to promote this archaeological record at a European scale, emphasizing its cultural and scientific dimensions. This project will benefit substantially from new intellectual challenges and training, which - will be gained at the UCL Institute of Archaeology. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ULP.PILAEMA - - - H2020-MSCA-IF-2016 - - - 740123 - - - - - UNIVERSITETET I BERGEN - UNIVERSITETET I BERGEN - - - EUR 2 278 884 - - - Humans On Planet Earth - Long-term impacts on biosphere dynamics - - - EUR 2 278 884 - - - Norway - Norway - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - A critical question in Earth system science is what was the impact of prehistoric people on the biosphere and climate? There is much information about human impact through clearance, agriculture, erosion, and modifying water - and nutrient budgets. Humans have greatly changed the Earth in the last 8000 years, but did humans modify the major ecological processes (e.g. assembly rules) that shape community assembly and dynamics? Did inter-relationships between processes - change in response to human impact? Lyons et al. & Dietl (2016 Nature) suggest that human activities in the last 6000 years had such impacts. Dietl proposes that using past ‘natural experiments’ to predict future changes is “flawed” and “out is - the use of uniformitarianism”. As using natural experiments is a common strategy and uniformitarianism is the major working concept in Earth sciences, it is imperative to test whether prehistoric human activity changed major ecological processes - determining community development. To test this hypothesis, patterns in pollen-stratigraphical data for the past 11,500 years from over 2000 sites across the globe will be explored consistently using numerical techniques to discern changes in 25 - ecosystem properties (richness, evenness, and diversity; turnover; rates of change; taxon co-occurrences, etc.). Patterns in these properties will be compared statistically at sites within biomes, between biomes, within continents, and between - continents to test the hypotheses that prehistoric human activities changed the basic ecological processes of community assembly and that their inter-relationships changed through time. These areas provide major contrasts in human prehistory and - biomes. HOPE is interdisciplinary: pollen analysis, databases, multivariate analysis, ecology, new statistical methods, numerical simulations, statistical modelling. HOPE’s impact goes beyond human effects on the biosphere and extends to the very - core of Earth science’s basic conceptual framework. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Norway - - - HOPE - - - ERC-2016-ADG - - - 741413 - - - - - UNIVERSITE LYON 1 CLAUDE BERNARD - UNIVERSITE LYON 1 CLAUDE BERNARD - - - EUR 2 091 000 - - - Advances in Research on Theories of the Dark Universe - Inhomogeneity Effects in Relativistic Cosmology - - - EUR 2 091 000 - - - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The project ARTHUS aims at determining the physical origin of Dark Energy: in addition to the energy sources of the standard model of cosmology, effective terms arise through spatially averaging inhomogeneous cosmological - models in General Relativity. It has been demonstrated that these additional terms can play the role of Dark Energy on large scales (but they can also mimic Dark Matter on scales of mass accumulations). The underlying rationale is that fluctuations - in the Universe generically couple to spatially averaged intrinsic properties of space, such as its averaged scalar curvature, thus changing the global evolution of the effective (spatially averaged) cosmological model. At present, we understand - these so- called backreaction effects only qualitatively. The project ARTHUS is directed towards a conclusive quantitative evaluation of these effects by developing generic and non-perturbative relativistic models of structure formation, by - statistically measuring the key-variables of the models in observations and in simulation data, and by reinterpreting observational results in light of the new models. It is to be emphasized that there is no doubt about the existence of backreaction - effects; the question is whether they are even capable of getting rid of the dark sources (as some models discussed in the literature suggest), or whether their impact is substantially smaller. The project thus addresses an essential issue of current - cosmological research: to find pertinent answers concerning the quantitative impact of inhomogeneity effects, a necessary, worldwide recognized step toward high-precision cosmology. If the project objectives are attained, the results will have a - far-reaching impact on theoretical and observational cosmology, on the interpretation of astronomical experiments such as Planck and Euclid, as well as on a wide spectrum of particle physics theories and experiments. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - France - - - ARTHUS - - - ERC-2016-ADG - - - 740021 - - - - - UNIVERSIDADE DE COIMBRA - - - EUR 160 635,60 - - - The role of aquatic hyphomycete spores in headwater stream food webs: a food quality approach. - - - EUR 160 635,60 - - - Portugal - - - Higher or Secondary Education Establishments - - The functioning of forested headwater streams relies on microbially-mediated processes ensured mainly by aquatic hyphomycetes. They are pivotal systems for human and other biotic communities as they provide water, carbon, and - nutrients. The scientific objectives of the Spor-oïkos project are to experimentally investigate: i) the chemical cues inducing aquatic hyphomycetes' sporulation, and ii) the functional role of aquatic hyphomycete spores in headwater food webs, both - being blind spots in freshwater ecology. By applying a food quality approach and merging different scientific disciplines and theories (molecular biology, biochemical and elemental theories), this project will unveil a potential hidden pathway of - nutrient and carbon (C) flow, offering new insights on the microbial contribution to large scale C fluxes. The biochemical theory studies the ecological role of essential molecules, mainly essential fatty acids and sterols. It is applied to - investigate the efficiency of C transfer in trophic interactions. The elemental theory studies how the ratios of elements in organisms (e.g. C, Phosphorus and Nitrogen) shape their ecology and nutrient and energy fluxes in ecosystems. Both theories - have successfully been applied to better understand the trophic interactions, and nutrient cycling in terrestrial and aquatic systems. In the last case, these theories have particularly been used to study the producer-consumer interaction in lakes, - and it is just recently that they are being applied in detritus-based systems such as headwater streams. This work programme will be articulate by four experiments that have carefully been designed to progressively understand the overlooked - importance of fungal spores in stream food webs, and the unknown effects of global changes (mainly eutrophication). Scientists from two high-level laboratories from two European countries will offer their expertise to train the researcher and hence - open up the best possibilities for his career. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Portugal - - - Spor-oikos - - - H2020-MSCA-IF-2016 - - - 746304 - - - - - FUNDACAO D. ANNA SOMMER CHAMPALIMAUD E DR. CARLOS MONTEZ CHAMPALIMAUD - - - EUR 148 635,60 - - - Neuronal MRI: Harnessing chemical exchange between N-Acetylaspartate and water for functional imaging of neural activity - - - EUR 148 635,60 - - - Portugal - - - Research Organisations - - Functional MRI (fMRI) is currently the leading noninvasive modality to assess brain function in vivo. However, it relies on a surrogate marker for neural activity –the hemodynamic responses following activity– which makes fMRI - nonspecific and difficult to interpret. Here, we propose to advance the state-of-the-art by developing and evaluating a methodology we term neuronal fMRI (nMRI) which would enable a direct measurement of neuronal activity and its fast dynamics. - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Portugal - - - Neuronal MRI - - - H2020-MSCA-IF-2016 - - - 753100 - - - - - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - - - EUR 150 000 - - - Nematode-based screening technology for next-generation drug discovery - - - EUR 150 000 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Alternative model organisms, such as worms or flies, are getting increasingly popular in the drug discovery field, since they are proving to be suitable for replacing mammals for several aspects of the screening tests in the - pre-clinical phase. In this context, one of the most interesting models is a roundworm species, named Caenorhabditis elegans. Its microscopic size, however, hinders its actual use in the field, since the protocols for its maintenance and study still - completely rely on manual handling/observation techniques, definitely lacking any reproducibility and throughput standards. - - - 2018-11-30, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Switzerland - - - NeMatrix - - - ERC-2016-PoC - - - 754375 - - - - - FCIENCIAS.ID - ASSOCIACAO PARA A INVESTIGACAO E DESENVOLVIMENTO DE CIENCIAS - FCIENCIAS.ID - ASSOCIACAO PARA A INVESTIGACAO E DESENVOLVIMENTO DE CIENCIAS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 999 275 - - - Competition under (niche) construction - - - EUR 1 999 275 - - - Portugal - Portugal - France - - - Research Organisations - Research Organisations - Research Organisations - - Interspecific competition is arguably the best interaction to address how individual trait variation and eco-evolutionary feedbacks shape species distributions and trait evolution, due to its indirect effects via the shared - resource. However, a clear understanding of such feedbacks is only possible if each contributing factor can be manipulated independently. With COMPCON, we will address how individual variation, niche width, niche construction and the presence of - competitors shape species distributions and trait evolution, using a system amenable to manipulation of all these variables. The system is composed of two spider mite species, Tetranychus urticae and T. ludeni, that up- and down-regulate plant - defences (i.e., negative and positive niche construction, respectively). Tomato mutant plants with low defences will be used as an environment in which niche construction is not expressed. Furthermore, tomato plants will be grown under different - cadmium concentrations, allowing quantitative variation of available niches. Using isogenic lines, we will measure individual variation in niche width, niche construction and competitive ability. Different combinations of lines will then be used to - test key predictions of recent theory on how such variation affects coexistence with competitors. Subsequently, mite populations will evolve in environments with either one or more potential niches, in plants where niche construction is possible or - not, and in presence or absence of competitors (coevolving or not). We will test how these selection pressures affect niche width, niche construction and competitive ability, as well as plant damage. Finally, we will re-derive isogenic lines from - these treatments, to test how evolution under different scenarios affects individual variation in niche width. - - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Portugal - - - COMPCON - - - ERC-2016-COG - - - 725419 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 998 802 - - - The Combined Effects of Climatic Warming and Habitat Fragmentation on Biodiversity, Community Dynamics and Ecosystem Functioning - - - EUR 1 998 802 - - - France - France - - - Research Organisations - Research Organisations - - Climatic warming and habitat fragmentation are the largest threats to biodiversity and ecosystems globally. To forecast and mitigate their effects is the environmental challenge of our age. Despite substantial progress on the - ecological consequences of climatic warming and habitat fragmentation individually, there is a fundamental gap in our understanding and prediction of their combined effects. - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - France - - - FRAGCLIM - - - ERC-2016-COG - - - 726176 - - - - - UNIVERSITY OF NEWCASTLE UPON TYNE - UNIVERSITY OF NEWCASTLE UPON TYNE - - - EUR 2 023 119 - - - Assisting Coral Reef Survival in the Face of Climate Change - - - EUR 2 023 119 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - CORALASSIST spans the disciplines of evolutionary biology, restoration ecology and proteomics and examines the role assisted gene flow (AGF) can play in sustaining biodiversity and ecosystem services in the face of climate - change. AGF involves the deliberate movement of individuals or gametes within their natural range to facilitate adaptation to environmental change. Corals reefs provide an excellent model for testing AGF as a conservation tool because reef building - corals are foundation species and are highly vulnerable to thermal stress. Selective breeding and translocation of thermotolerant individuals may lead to reductions in recipient population fitness due to resource trade-offs with other fitness traits, - such as growth and fecundity. The overall aim of CORALASSIST is to establish the feasibility of implementing AGF in coral reef ecosystems using a combination of selective breeding, proteomics and innovative translocation techniques. CORALASSIST will - address four primary questions: 1) Are there resource trade-offs between increased thermotolerance and other fitness traits in corals? 2) Which physiological and proteomic traits correlate with increased individual thermotolerance in corals? 3) Are - phenotypic traits for thermotolerance heritable? 4) Can AGF and selective breeding lead to persistent shifts in thermotolerance in recipient populations? Phenotypic traits will be measured in permanently tagged individuals within selected coral - populations to examine the relationships between thermotolerance and key fitness attributes. For the first time, state of the art proteomic approaches will be used to elucidate the physiological basis for increased levels of thermotolerance in - corals. Innovative translocation methods will be used in tandem with selective breeding techniques to carry out the first long term assessment of heritability of thermotolerance and to test the feasibility of large scale AGF to assist conservation of - coral reef ecosystems. - - 2022-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - CORALASSIST - - - ERC-2016-COG - - - 725848 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 1 903 685 - - - Design of NanoMOFs Capsules for Drug Delivery and Bioimaging. - - - EUR 1 903 685 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Cancer is a major health problem worldwide, being the most common cause of death after cardiovascular diseases. The major goal of new anticancer therapies is to specifically kill tumour cells while leaving healthy cells - unharmed. A main challenge to achieve this aim is the development of better drugs, including novel treatments based on the use of siRNAs. These macromolecules are potentially the most powerful anti-cancer drugs that exist, but still there is no - efficient way of getting them delivered specifically to the tumour. Indeed, lifetime of such molecules is generally too short and therefore need to be protected in a carrier until they are delivered into tumour target cells. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - NanoMOFdeli - - - ERC-2016-COG - - - 726380 - - - - - GOETEBORGS UNIVERSITET - - - EUR 173 857,20 - - - Experimental Study of Three-dimensional Dynamics of Active Particles - - - EUR 173 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - Active particles are microscopic objects capable of self-propulsion. Examples include natural microorganisms, e.g. motile bacteria, chemotactic cells, and artificial colloidal microswimmers. From the fundamental side, their - study can shed light on the far-from-equilibrium physics underlying the adaptive and collective behavior of microscopic biological entities. From the more applied side, they provide tantalizing options to perform tasks not easily achievable with - other available techniques, such as the targeted localization, pick-up and delivery of microscopic cargoes, e.g., in drug delivery, bioremediation and chemical sensing. Despite the ever-growing interest that active particles have arisen in the - scientific community, almost all experimental studies have focused on quasi-two-dimensional investigations, mainly because of limitations in the employed microscopic techniques. Nevertheless, the three-dimensional (3D) dynamics and behavior of active - particles can be qualitatively different, as has already been shown by numerical and theoretical studies; this is particularly true when considering active particles moving in 3D complex and crowded environments. With this project, I will fill this - gap by developing an experimental technique capable of investigating the motion of active particles in 3D. First, I will implement a state-of-the-art 3D super-resolution microscope (high-frame rate, large field of view). Then, I will use it to - characterize the 3D motion of single active particles in homogenous environments. Finally, I will study their motion in complex and crowded environments similar to the ones that can be found in nature or in applications; this will permit me to - explore and develop effective strategies to control the motion of active particles in these environments. This will pave the way towards a deeper understanding of the behavior of active particles and also towards realistic applications. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - ACTIVEMOTION3D - - - H2020-MSCA-IF-2016 - - - 745823 - - - - - CONSIGLIO NAZIONALE DELLE RICERCHE - - - EUR 2 746 800 - - - INnovative Life sCIence Phd Programme in South ITaly - - - EUR 5 493 600 - - - Italy - - - Research Organisations - - INCIPIT is a novel international PhD programme, which aims at providing innovative multidisciplinary and intersectoral training in Life and Biomaterial Sciences. Currently, there are several nodes of excellence in the South of - Italy, capable of providing competitive scientific training. However, comprehensive training programmes addressing multidisciplinarity, transferable skills and internationalization are lacking. INCIPIT addresses this gap by pooling the different and - complementary expertise of 8 research institutes (from biology and genetics to statistics, engineering, computer science, chemistry and medicine) of the Consiglio Nazionale delle Ricerche (CNR), as well as the competencies of 3 Doctoral Schools and - several academic, non-profit and industrial Partner Organizations. INCIPIT will apply transparent and equitable selection procedures, based on merit and on equal opportunities to recruit 35 Early Stage Researchers. INCIPIT will guarantee 1) a - supportive, stimulating and multidisciplinary research environment to carry out the research projects; 2) theoretical and practical courses on developmental/stem cell biology and regenerative medicine, structural biology and biocatalysis, human - disease mechanisms, cancer development and treatment, metabolism and inflammation, drug design, discovery and delivery, and computational biology; 3) a comprehensive training on transferable skills on several topics, from communication, project - management, clinical trials, the principle of the 3 Rs for the use of animals, to intellectual properties and entrepreneurship; and 3) exposure to the industry sector. The ultimate goal is to train the next generation of researchers to become a very - attractive source of employment in both the Italian and European labour markets. INCIPIT will be a pilot project, paving the way to the consolidation in the South of Italy of an international PhD programme, with close collaboration among the CNR, the - Universities and the industrial sector. - - 2020-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2014-DP - Marie Skłodowska-Curie Co-funding of regional, national and international programmes (COFUND-DP) - - - MSCA-COFUND-DP - Doctoral programmes - - - Italy - - - INCIPIT - - - H2020-MSCA-COFUND-2014 - - - 665403 - - - - - CENTRALESUPELEC - - - EUR 173 076 - - - scalaBle and grEen wireleSs coMmunications for a sustAinable netwoRked socieTy - - - EUR 173 076 - - - France - - - Higher or Secondary Education Establishments - - The goal of the project is to develop energy-efficient and scalable designs for distributed mobile networks operated by renewable energy sources, and with very limited signaling overhead and computational complexity. The - project will design wireless networks, composed by smart nodes, which are able to perform the following tasks: - - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - BESMART - - - H2020-MSCA-IF-2016 - - - 749336 - - - - - CENTRE DE COOPERATION INTERNATIONALE EN RECHERCHE AGRONOMIQUE POUR LEDEVELOPPEMENT - C.I.R.A.D. EPIC - CENTRE DE COOPERATION INTERNATIONALE EN RECHERCHE AGRONOMIQUE POUR LEDEVELOPPEMENT - C.I.R.A.D. EPIC - INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT - - - EUR 1 993 281 - - - Revolutionizing Insect Control - - - EUR 1 993 281 - - - France - France - France - - - Research Organisations - Research Organisations - Research Organisations - - EFSA recently prohibited 75% of insecticides to account for their toxicity and ecotoxicity. Moreover, the spread of insecticide resistance and invasion of Europe by new tropical vectors and pests require the development of - alternative biological techniques. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - France - - - REVOLINC - - - ERC-2015-CoG - - - 682387 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 183 454,80 - - - Writing Jewish History: Ancient Judaism as a Political Problem in Central Europe at the Rise of the Nation State - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - AJAPP investigates the integration of religious minorities amid the rise of nation-states in Central Europe in the late modern period. Specifically, AJAPP focuses on political representation of ancient Judaism by Catholics, - Jews, and Protestants throughout Prussia, Austria, and Bavaria in the course of the 19th century. The goal is to understand how portraits of the past reflected both the concerns and the conditions of modern times and, in turn, how these portraits - impacted contemorary debates on issues of national, cultural, religious, and ethnic identity. It analyses how political and social differences - as opposed to strictly ethnic or cultural ones - as well as subtle prejudices manifested themselves in - discussions of the past, how boundaries were made within a shared tradition, and how identities were configured in regional and national entities. This period is especially imortant as this was a time when distinct regions were negotiating their - political relationships to one another (often with violence), when public discourse was debating which communities had which stakes in and rights to the political realm, and when the past became especially contested territory for determining which - groups were insiders and which ones were outsiders. Given the current rise in regionalism, nationalism, and right-wing extremism across Europe, AJAPP addresses a central problem palpable on the local, international, and global levels today. It - reveals how implicit assumptions inscribe the conceptualisation of the past, which then find their way back into the present. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - AJAPP - - - H2020-MSCA-IF-2016 - - - 749628 - - - - - FONDS NATIONAL DE LA RECHERCHE - - - EUR 150 000 - - - Luxembourg EU Presidency Conference 2015 on MSCA COFUND, 10-11 December 2015 - - - EUR 191 250 - - - Luxembourg - - - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - Under Luxembourg's EU presidency in the second half of 2015, the National Research Fund (FNR) is organising a high visibility international conference on the theme of COFUND in the framework of the Marie Sklodowska-Curie Actions. - - - 2016-01-31, closed project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3."> - - - MSCA - MSCA - - - CSA - Coordination and support action - - - Luxembourg - - - MSCA2015 - COFUND - - - H2020-Adhoc-2014-20 - - - 692700 - - - - - DANMARKS TEKNISKE UNIVERSITET - - - EUR 212 194,80 - - - High Current All Printed Transistors - - - EUR 212 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - The fast evolution of printed electronics, with the photovoltaic technology in primis, is requiring the presence of a valid transistor alternative to the traditional one. The realization of a high current roll-to-roll - transistor will interconnect all the different technologies so far developed with this low cost and high throughput method. Our aim is to develop a roll-to-roll transistor capable to of modulate modulating the current to levels that where has not - been achieved so far. The fabrication of the transistor will be done considering the lowest environmental impact possible, and containing energy consumption with a temperature below 150 °C. This high current (~mA) transistor will be able to support - and assist other technologies and will also be the base for logics and sensing application. - - 2017-04-30, closed project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - HCAPT - - - H2020-MSCA-IF-2014 - - - 659747 - - - - - UNIVERSITY OF NEWCASTLE UPON TYNE - - - EUR 183 454,80 - - - Spaces of Anti-Muslim Acts in the Greater Paris and Greater London regions - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Social and political debates have repeatedly shown that we are now in a new religious era primarily marked by diversity. The religious diversity of European society – and in particular the visibility of Muslims in the public - space – reveals that the geographical space is a key factor in the study of anti-Muslim discrimination. Indeed, Islamophobia is very much present and has intensified especially since the armed attack of Charlie Hebdo publishing offices (a French - satirical magazine) in January 2015. By analysing the spatial effects of Islamophobia, we seek to more effectively assess the impact of Muslim presence throughout European society, and in particular in France and United Kingdom. More exactly in the - SAMA project, I will identify the spaces where anti-Muslim acts have occurred, the spatial practices and the scales of belonging of these discriminated people, and the intersectional dimension of Islamophobia in both the Greater Paris and Greater - London regions. In addition to recording the highest levels of anti-Muslim acts , these conurbations are also “socio-spatial laboratories” that offer a useful context for exploring and understanding the dynamics that revolve around religious - discrimination. To do this, the researcher - Dr Kawtar NAJIB - is moving from France to Newcastle University in United Kingdom in order to undertake a research on “spaces of anti-Muslim acts in the Greater Paris and Greater London regions”. This - project will offer significant insights for the fight against racism and hate crimes in Europe. The researcher will gain research expertise in Islamophobia, social geographies, inter-European comparative research and GIS (Geographical Information - Systems). - - 2018-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - United Kingdom - - - SAMA - - - H2020-MSCA-IF-2015 - - - 703328 - - - - - BIRKBECK COLLEGE - UNIVERSITY OF LONDON - - - EUR 183 454,80 - - - Reasonable Doubt: An epistemological and psychological approach - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The purpose of this research is to shed light on the nature and dynamics of doubt and confidence in complex epistemic decision-making, through a study of the notion of reasonable doubt. While doubt is considered a rational - virtue, waiting until complete certainty before accepting and acting upon a given hypothesis is unreasonable in many contexts. Given some evidential support for the hypothesis, the threshold beyond which acceptance rather than doubt is the reasonable - option seems to depend on the decisional context (particularly the cost of a possible error): jurors in criminal trials should thoroughly consider alternative scenarios before convicting a defendant; doctors or policy-makers, however, may have to - take action upon less strongly confirmed hypotheses, depending on the relative costs and benefits of action/inaction. Such a decision-theoretic view of reasonable doubt relies on the assumption that the consequences of an hypothesis are exogenous to - the rational evaluation of its evidential support: one first updates one’s degree of belief in view of the evidence, and then assesses whether, given the context, the hypothesis is beyond reasonable doubt (i.e. should be accepted and acted upon). But - is it the case that agents’ degrees of confidence in a hypothesis, and their weighing of various pieces of evidence, are impermeable to the decisional context? Is the juror’s actual belief independent from her having to bring a consequential verdict? - This research aims to study the epistemological norms of reasonable doubt, taking account of the psychological reality of the agents’ reasoning. The main objective of the fellowship is to develop an original empirical research programme, testing the - effects of the consequentiality of epistemic decisions on reasoning. This interdisciplinary project requires the candidate, an expert philosopher, to acquire experimental skills and knowledge in psychology, under the supervision of a specialist in - the psychology of reasoning. - - 2017-08-31, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ReaDoubt - - - H2020-MSCA-IF-2014 - - - 660187 - - - - - INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT - - - EUR 178 603,20 - - - Understading the Maize Epigenome and its Role in Development - - - EUR 178 603,20 - - - France - - - Research Organisations - - Phenotypes are largely determined by genetic factors. However, a given genotype can give rise to very distinct phenotypes, as exemplified by the diversity of cell types in multicellular organisms. This phenotypic plasticity - results from epigenetic changes; that is, reversible modifications to the DNA molecule and its associated proteins that modulate gene expression patterns. Epigenetic changes are critical to the establishment of developmental programs, but also to - adjust transcription in response to the environment. The latter is particularly important for plant adaptation: owing to a sessile (immobile) lifestyle, plants cannot run away from adversity, and thus adapt to their environment by tuning gene - expression in response to changing conditions. Most epigenetic information is erased from one generation to the next, so that new organisms start their life cycle with a “fresh” potential. However, there are instances in nature of heritable - epigenetic marks that can be transmitted to the next generation. Thus, owing to their role in shaping gene expression, and the potential for heritable changes, epigenetic factors are of great interest for plant breeders, in their quest for adaptable, - high yielding phenotypes. Most of our current understanding of epigenetic processes in plants has been developed in Arabidopsis, a key model system. However, the Arabidopsis epigenome is rather idiosyncratic, and this knowledge might translate poorly - to crops. Here, we will use an interdisciplinary approach combining original genetic materials and bioinformatics to analyze epigenetic regulatory pathways in maize, with a focus on reproductive development. Maize is an important model plant, with a - large and dynamic epigenome much more typical of crops. It is also a crop of great economic importance. Better understanding the epigenome of maize will open the door to the manipulation of key agronomic traits, including reproductive development, - which is under strong epigenetic influence. - - 2017-07-31, closed project - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - France - - - EPIMAIZE - - - H2020-MSCA-IF-2014 - - - 658900 - - - - - INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT - WEST AND CENTRAL AFRICAN RESEARCH AND EDUCATION NETWORK - GEANT LIMITED - GROUPEMENT D INTERET PUBLIC POUR LERESEAU NATIONAL DE TELECOMMUNICATIONS POUR LA TECHNOLOGIE L ENSEIGNEMENT ET LA RECHERCHE - CENTRE DE COOPERATION INTERNATIONALE EN RECHERCHE AGRONOMIQUE POUR LEDEVELOPPEMENT - C.I.R.A.D. EPIC - SIGMA ORIONIS SA - BRUNEL UNIVERSITY LONDON - THE UBUNTUNET ALLIANCE FOR RESEARCH AND EDUCATION NETWORKING - COOPERACION LATINOAMERICANA DE REDES AVANZADAS - - - EUR 1 217 982,50 - - - TransAfrican Network Development - - - EUR 1 217 982,50 - - - France - Ghana - United Kingdom - France - France - France - United Kingdom - Netherlands - Uruguay - - - Research Organisations - Other - Other - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - - The TANDEM project aims to create favourable conditions for WACREN (West and Central African Research and Education Network) to be able to participate in the forthcoming AfricaConnect project extension and to draw maximum - benefit from it, and thereby to ensure WACREN’s integration into the global Research and Education networking community. TANDEM long-term goal is to make it possible for researchers and academics to contribute with their peers around the world to the - socio-economic development of the West and Central African Region. To this end, TANDEM is structured around three objectives: - - 2017-04-30, closed project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.3."> - - - INFRASUPP-7-2014 - e-Infrastructure policy development and international cooperation - - - CSA - Coordination and support action - - - France - - - TANDEM - - - H2020-INFRASUPP-2014-2 - - - 654206 - - - - - UNIVERSITY OF LEEDS - - - EUR 183 454,80 - - - Catchments under Pressure: Ecosystem Service Solutions - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Catchments are under pressure from impacts on demand and supply and within these constraints water resource managers are challenged to meet multiple and often competing values. The ecosystem services (ES) approach has - attracted policy interest as it connects natural capital and the ES flows it supports with human wellbeing. There exists a policy window to translate detailed case study assessment into workable solutions for catchment management in times of change - in Europe and beyond. ES research to protect and foster sustainable management of natural resources and ecosystems and the multiple ES they supply fits within the Horizon 2020 programme on Societal Challenges. - - - 2017-06-30, closed project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - CuPESS - - - H2020-MSCA-IF-2014 - - - 659449 - - - - - VASTRA GOTALANDS LANS LANDSTING - - - EUR 708 000 - - - Mobility for Regional Excellence 2020 - - - EUR 1 416 000 - - - Sweden - - - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - MoRE2020 is a continuation and further development of the FP7-Marie Curie-COFUND programme called “Mobility for Regional Excellence” (MoRE), which Region Västra Götaland was granted in December 2013 (grant agreement no - 608743). The half-term external evaluation of the MoRE programme indicated very positive results. - - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2016 - Co-funding of regional, national and international programmes - - - MSCA-COFUND-FP - Fellowship programmes - - - Sweden - - - MoRE2020 - - - H2020-MSCA-COFUND-2016 - - - 754412 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 1 726 560 - - - DOCtoral training programme in Functional Advanced Materials - - - EUR 3 453 120 - - - Spain - - - Research Organisations - - DOC-FAM is a COFUND Doctoral Programme with a duration of 60 months presented by the Spanish National Research Council (CSIC) and coordinated through the Institute of Materials Science of Barcelona (ICMAB). The main aim of the - programme is the training of 22 early-stage researchers during 36 months each as the next-generation of scientists in the exciting field of Functional Advanced Materials, while at the same time offering a complete training experience to the recruited - fellows. This doctoral programme builds up on the recent award obtained by ICMAB as one of the 22 “Severo Ochoa Centres of Excellence”, an award given by the Spanish Government that recognizes institutions from all areas of knowledge that perform - cutting-edge research at world standards. The award as “Severo Ochoa Centre of Excellence” to develop “Smart Functional Materials for Social Grand Challenges” (FUNMAT, 2016-2019) demonstrates the outstanding international scientific leadership of - ICMAB in the field of Advanced Functional Materials and Nanomaterials. The aim of the research programme offered in DOC-FAM is to complement the training aspects of FUNMAT by offering the recruited fellows an excellence training programme in the - bourgeoning field of Functional Advanced Materials through an interdisciplinary, intersectorial and international approach with the support of several partner organisations from the area, four of them contributing to the co-funding of the doctoral - programme. The designed training programme combines different types of activities that will enhance their research and personal skills, providing them with new career perspectives. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2016 - Co-funding of regional, national and international programmes - - - MSCA-COFUND-DP - Doctoral programmes - - - Spain - - - DOC-FAM - - - H2020-MSCA-COFUND-2016 - - - 754397 - - - - - CORK INSTITUTE OF TECHNOLOGY - UNIVERSITY OF ULSTER - FTK FORSCHUNGSINSTITUT FUR TELEKOMMUNIKATION UND KOOPERATION EV - GLOBIT-GLOBALE INFORMATIONSTECHNIKGMBH - INMARK EUROPA SA - - - EUR 504 000 - - - Sensor Enabled Affective Computing for Enhancing Medical Care - - - EUR 504 000 - - - Ireland - United Kingdom - Germany - Germany - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - This project brings together a diverse group of subject matter experts from industry and academia under one umbrella, with the main aim of enhancing and advancing future healthcare processes and systems using sensory and - machine learning technologies to provide emotional (affective) and cognitive insights into patients well-being so as to provide them with more effective treatment across multiple medical domains. The objective is to develop technologies and methods - that will lessen the enormous and growing health care costs of dementia and related cognitive impairments that burden European citizens, which is estimated to cost over €250 Billion by 2030 [1]. - - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Ireland - - - SenseCare - - - H2020-MSCA-RISE-2015 - - - 690862 - - - - - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - FIBERCRYST SAS - JUSTUS-LIEBIG-UNIVERSITAET GIESSEN - FYZIKALNI USTAV AV CR V.V.I - UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA - PRYSMIAN - Intelligentsia Consultants Sàrl - - - EUR 922 500 - - - International and intersectoral mobility to develop advanced scintillating fibres and Cerenkov fibres for new hadron and jet calorimeters for future colliders - - - EUR 1 093 500 - - - Switzerland - France - France - Germany - Czech Republic - Italy - Italy - Luxembourg - - - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Currently, new concepts are being considered for hadron and jet calorimetry in high energy physics experiments, in order to improve the energy resolution of these detectors by a factor of at least two. This is a prerequisite - for future studies at the high luminosity, large hadron collider as well as at future electron and proton colliders. Amongst the few concepts being proposed, scintillating and Čerenkov fibres are considered very promising candidates. - - 2019-02-28, ongoing project - - - 2015-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Switzerland - - - INTELUM - - - H2020-MSCA-RISE-2014 - - - 644260 - - - - - THE QUEEN'S UNIVERSITY OF BELFAST - - - EUR 195 454,80 - - - FUTURE-PROOF: Wide Area Monitoring and Protection Systems for the Future Grid - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - This project seeks to advance the state-of-the-art in wide-area power system monitoring and protection systems, a critical component of future power systems, and vital to achieving the EU vision of a European Energy Union that - delivers secure, affordable and climate-friendly energy. Crucially, the fellowship will bring together the complementary expertise of the applicant on power system protection, with the host organisation’s state-of-the-art wide-area monitoring - infrastructure, and technical expertise in measurement technology, machine learning and big data analysis, enabling innovative research at the interface between these domains. Outputs will take the form of peer-reviewed journal articles and - international conference papers setting out algorithms, and methodologies for robust and scalable monitoring and protection of future grids, and a power industry engagement workshop for knowledge transfer to key stakeholders. - - - 2020-02-14, Grant Agreement signed - - - 2018-02-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - FUTURE-PROOF - - - H2020-MSCA-IF-2016 - - - 751893 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 173 076 - - - Solid-State Multi-Photon Sources for Larger-Scale Quantum Optics and Photonics - - - EUR 173 076 - - - France - - - Research Organisations - - Optical quantum technologies are at the forefront of a forthcoming second quantum revolution, where advances in quantum photonics at the single-photon level are enabling new technologies at accelerating pace: from applications - for secure quantum communication, to the realization of quantum simulation and quantum computation protocols. The scaling of quantum photonics, however, has long been restrained by low efficiencies in current photon sources, what limits the - complexity of the protocols that are being demonstrated. The host team has very recently succeeded in the fabrication of solid-state single-photon sources about 20 times more efficient than current alternatives. These sources have reached the best - possible performance in terms of purity and indistinguishability, as required for scalable applications. In this proposal, the high performance of these devices is combined with the expertise in quantum optics of the applicant to advance the - state-of-the-art in quantum photonics to the efficient and high-rate manipulation of multiple single-photons. A new era of larger-scale quantum photonics will be attained by enabling the manipulation of multiple photons past the qubyte threshold of 8 - photons. The project will include the demonstration of 10-photon sources with sub-Hertz detection rates; the implementation of heralded entangling gates run at unprecedented rates; as well as the demonstration of multi-photon interference with up to - 8-photons in a Boson Sampling machine. This project will thus importantly advance upon the complexity of current multi-photon research, opening a new era of solid-state based quantum optics and photonics. - - 2019-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - SMuPhoS - - - H2020-MSCA-IF-2016 - - - 750886 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 270 918 - - - Toward a new generation of Ecological Assessment tools for the Management Coastal environment - - - EUR 270 918 - - - France - - - Research Organisations - - Marine coastal areas have a considerable socio-economic importance and provide multiple services to Humankind (fisheries, nutrient cycling etc.). However, these environments are subjected to multiple anthropogenic pressures - that are profoundly modifying benthic communities (i.e. organisms living on, in, or near the seabed as invertebrates, algae, bacteria etc.) that control most coastal ecosystem services. The TEAM-Coast project aims to develop a new generation of - tools, based on emerging environmental genomics approaches (i.e. the study of genetic material retrieved in environmental samples), to investigate responses of coastal communities to stressors and assist stakeholders to make informed decisions - regarding the balance between human activities and ecological integrity of coastal environments. Preserving efficiently these environments requires: 1) to integrate all coastal biodiversity in studies and models, a large portion being generally - excluded due to technical and financial constraints; 2) to treat anthropogenic pressures in a integrated way to understand the full ecological ramifications of the multiple stressors in interaction on the structure and functioning of communities; 3) - to rank the relative importance of these stressors to prioritize actions to lead. This project proposes thus to take advantage of the promises of environmental genomics to characterize the whole range of benthic communities over broad scales, at a - unprecedented level of details and in a standardised, rapid and cost-effective way. These approaches will be implemented at the seascape scale to disentangle and understand ecological ramifications of multiple human-induced stressors on structure and - diversity of benthic communities. Data will be then combined with cutting-edge statistical tools to identify key stressors and develop innovative management strategies. As such, outcomes of TEAM-Coast will lead to major advances for monitoring and - management of European coastal environments. - - 2021-07-15, Grant Agreement signed - - - 2018-07-16 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - France - - - TEAM-Coast - - - H2020-MSCA-IF-2016 - - - 750570 - - - - - UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6 - - - EUR 173 076 - - - Resource Sensitive Quantum Computing - - - EUR 173 076 - - - France - - - Higher or Secondary Education Establishments - - Quantum Computing has been a subject of huge interest in recent years, from researchers and the general public alike, due to its intriguing potential for applications which will forever be beyond the reach of classical - computing. Despite recent progress in both experimental and theoretical techniques, difficulties in communicating the needs and results of these respective camps has resulted in a lack of major implementable applications for near-term technologies. - This action aims to change the field multilaterally, from developing novel tools to deal with critical practical issues hindering implementation through to a first resource sensitive theoretical approach to finding applications with technological - practicalities at its core. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - ResQu - - - H2020-MSCA-IF-2016 - - - 750523 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - - - EUR 175 866 - - - For a better understanding and design of ferroelectric photovoltaics: First-principles study of opticalabsorption and charge-carrier transport at ferroelectric domain walls in BiFeO3 - - - EUR 175 866 - - - Ireland - - - Higher or Secondary Education Establishments - - The goal of this project is to help find the rules for a domain-wall engineering that optimizes photovoltaic efficiency of potential future-generation ferroelectric solar cells. The material to be studied is BiFeO3 as the most - promising photovoltaic ferroelectric material known. Does the photovoltaic effect in BiFeO3 occur at the domain walls or in the bulk? What does it take a domain-wall to conduct electrons? The project aims - - 2019-06-14, ongoing project - - - 2017-06-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Ireland - - - FERROVOLT - - - H2020-MSCA-IF-2016 - - - 746964 - - - - - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - - - EUR 251 857,80 - - - USLAMISM:The United States and Political Islam: A Historical and Contemporary Perspective. - - - EUR 251 857,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - At a time when various Islamist groups are in close proximity to power, this project aims to examine the relations between the US and forces aligning themselves with Islamism . It is meant to understand the mechanisms of US - policy towards this ideology. What are the issues arising from the diplomatic relations linking the US power and the representatives of an ideology traditionally opposed to them? What conceptions of Islamism –both historical and contemporary– has - been guiding US foreign policy? The research process will be structured along two dimensions. The first is a historical investigation based on State Department and Presidential archives and sources handed down by US foreign policy practitioners - dealing with Islamism over several decades. The second dimension consists of an examination of the contemporary state of play using interviews, discourse analysis and a study of US foreign policy actions towards Islamist forces. USLAMISM is original - in three ways. - - - 2020-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - USLAMISM - - - H2020-MSCA-IF-2016 - - - 750833 - - - - - THE UNIVERSITY OF HUDDERSFIELD - - - EUR 195 454,80 - - - using Virtual Reality and Archaeoacoustic Analysis to Study and exhibit Presence - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - Denise Ogden - Tel.: +44-1484-473192 - Fax: +44-1484-472682 - - Unusual acoustic signatures of ancient or historical spaces, such as the West Kennet Long Barrow in England; caves in northern Spain containing prehistoric art; or Sculptor's Cave in Scotland, have captured the public - imagination for centuries. Attentive listeners often hear or feel a presence or resonance within such acoustic spaces, sometimes described as an otherness, a shimmer or glow, or an audio-visual aesthetic experience of the space. There is evidence - that this sense of presence is brought on by the perceptual conflation of where and what streams of information in the brain. Other acoustic incongruities (such as infrasound) play a role in the experience of spaces and the acoustic experience of - presence contributes to the phenomenology of historical and archaeological sites. The perception of presence is especially common in historically sacred locations (and shimmer is a characteristic descriptor of the spiritual realm), and thus acoustic - analysis of the phenomenology of presence provides insight into the source of this experience. Acousticians, composers, and acoustic archaeologists have studied acoustic phenomena, and archaeologists have compiled 3D models of archaeological sites - for cultural preservation and exhibition purposes. The ER will use these technologies to engage in creative practice-led research on the phenomenology and acoustic archaeology of space. This research will contribute new knowledge on the phenomenology - and psychoacoustics of archaeological spaces, and will also improve virtual archaeological spaces by imbuing them with their original sense of presence. Through this project the ER will develop skills in 3D visual and acoustical modelling, VR - simulation, numeracy, data analysis, sound reinforcement, publication preparation, presentation, and dissemination. Throughout the fellowship, the ER will undertake field work at 5 archaeological sites, publish 1 paper and 1 studio report, present at - 2 conferences, and organise a performance. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - VRAASP - - - H2020-MSCA-IF-2016 - - - 750618 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 173 212,20 - - - Mobility in situ: Debating emigration and return in Western Mali - - - EUR 173 212,20 - - - France - - - Research Organisations - - Located in Western Mali, at the junction with Senegal and Mauritania, the area of Kayes has a long history of sustained involvement in transnational migration, notably towards France. The region bears the material and social - imprints of decades of international migration in its infrastructures, buildings, family relations, and local notions of success and failure. Though this migration and its social effects have been the topic of a wide range of studies, the local - understandings and discussions of these dynamics have been under-researched. Dwelling on developments in anthropology and African studies that highlight the importance of local expressive practices, this project focuses on three arenas where - emigration and, more specifically, return have been debated: a village created by returnees in 1977; a local radio initiated by emigrants in 1987; individual trajectories of returnees from France to one village. In each field-site, biographical - narratives will be combined with corpora of local productions of distinct sorts: personal documents such as family letters or cassettes; public discourses such as listeners’ letters to the radio and songs; and personal archives including photographs. - The project will discuss the issue of return, a heavily politically and morally loaded one, by bringing together the individual and collective stories of returnees from distinct generations (those returning as adults in the 1970s and those returning - in the 2000s), and the public discourses of each time. It will also question the way it is currently memorialized. While contributing to anthropological discussions on return migration, the ambition of the project is also to offer a better - understanding of a key zone of emigration to Europe. Since the European Union is committed to address the root causes of migration, and funds initiatives to prevent migration, providing knowledge on local debates on migration can offer resources for - designing effective programs in this field. - - 2020-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - France - - - MOBILIMA - - - H2020-MSCA-IF-2016 - - - 749223 - - - - - UNIVERSITE DE LILLE II - DROIT ET SANTE - - - EUR 173 076 - - - Glucotanycytes: a role for hypothalamic barriers in the control of metabolism by peripheral glucose - - - EUR 173 076 - - - France - - - Higher or Secondary Education Establishments - - "The escalating epidemic of obesity, type-2 diabetes and metabolic syndrome represents one of the most pressing and costly biomedical challenges confronting modern society. The impaired action of peripheral hormones on brain - circuits controlling feeding and energy homeostasis, also known as "central hormone resistance", is increasingly recognized as playing a role in the pathophysiology of these disorders. The host laboratory has raised the groundbreaking notion that - tanycytes, a specific type of hypothalamic glial cells, act as "gatekeepers" that regulate the access of blood-borne signals to the hypothalamus, and in particular, their vesicular transport into the cerebrospinal fluid, from where they enters other - metabolic-hormone-sensitive regions. The overall objective of this proposal is to further develop this highly original angle by using state-of-the-art approaches to i) gain new insights into the molecular mechanisms underlying structural changes in - the tanycytic barrier in response to fluctuating concentrations of circulating glucose, and determine how these processes are altered in animal models with acquired type-2 diabetes, and ii) explore the possibility that tanycytes are involved in the - shuttling of circulating glucose into the cerebrospinal fluid (CSF) and that the tanycytic expression of the NMDA receptor plays a role in this process. This research promises to shed new light on the molecular mechanisms used by the hypothalamus to - integrate key peripheral signals and coordinate energy homeostasis. The results will pave the way for the development of new treatment strategies to overcome hormone resistance in human obesity and associated metabolic syndromes." - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - GLUCOTANYCYTES - - - H2020-MSCA-IF-2016 - - - 748134 - - - - - FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA - - - EUR 244 269 - - - Re-Empower the BOdy after Tetraplegia. - - - EUR 244 269 - - - Italy - - - Research Organisations - Chiara Andreoli - Tel.: +3901071781854 - Fax: +39 010 7170817 - - REBoT will move its steps towards the understanding of the interrelationships between training-induced brain reorganization and sensorimotor function after cervical spinal cord injury (SCI). The final goal is to promote a - “rewiring” of the cortex (or supra-spinal circuits) to bypass pathways interrupted by SCI through a progressive adaptation of the rehabilitative intervention. - - 2020-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Italy - - - REBoT - - - H2020-MSCA-IF-2016 - - - 750464 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 185 076 - - - Testing Cosmic Inflation and Reheating in the Very Early Universe - - - EUR 185 076 - - - France - - - Research Organisations - - The aim of this cosmology proposal is to study the physical conditions that prevailed in the early Universe where a phase of accelerated expansion, “inflation”, took place. I will design a comprehensive pipeline to identify - the early Universe models for which the data show the strongest preference. I also propose to use new methods to unveil quantum signals in inflationary observables and use inflation as a quantum laboratory on cosmological scales. I will also extend - the range of current and future data sets that can be used to constrain inflation, and derive forecasts for future missions. - - - 2019-06-06, ongoing project - - - 2017-06-07 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - TESTINF - - - H2020-MSCA-IF-2016 - - - 750491 - - - - - THE UNIVERSITY OF NOTTINGHAM - - - EUR 183 454,80 - - - Studies of Materials and Catalysts by Dynamic Nuclear Polarization Enhanced Solid-state NMR - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Recent innovations in dynamic nuclear polarization (DNP) have transformed the sensitivity of solid-state nuclear magnetic resonance (NMR), resulting in a reduction in experiment time of up to 100,000-fold. This means that - previously unobtainable structural details can be quickly obtained by NMR, even for dilute species, such as binding sites in catalysts or functionalizing molecules at surfaces. The objectives of the action are the improved sample preparation - protocols, new experimental approaches and proof of principle studies necessary to make DNP-enhanced solid-state NMR the method of choice for the molecular-level characterization of the surfaces of materials. These objectives will be achieved by - knowledge exchange between Dr S. Chaudhari, an experienced researcher with a background in developing DNP, and researchers at the University of Nottingham involved in solid-state NMR studies of materials and catalysts. The action is designed to train - Dr Chaudhari though high-quality research into applications of DNP-enhanced solid-state NMR to four technologically useful materials: mesocellular silica foams, alumina catalyst supports, surface-coated hydroxyapatite nanoparticles and model - catalytic converters. The training will take place at the state-of-the-art UK Facility for DNP-enhanced solid-state NMR operational at the University of Nottingham since November 2015. The Facility’s instrumentation is unique in the UK and is - available to external users from both industry and academia, resulting in a vibrant research environment and a ready-made network of collaborators for Dr Chaudhari. In addition, a secondment at a leading sustainable technology company (Johnson - Matthey) will ensure that industrial and commercial aspects are fully integrated into the action. The training will transform Dr Chaudhari into a creative and independent scientist working at the frontiers of DNP-enhanced NMR by providing him with - the necessary research knowledge and transferable skills. - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - DNPMAT - - - H2020-MSCA-IF-2016 - - - 747208 - - - - - UNIVERSIDAD PABLO DE OLAVIDE - - - EUR 170 121,60 - - - Whispering the language of the neurons to restore vision - - - EUR 170 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - Visual neuroprostheses or the bionic eyes, aim to restore patterned vision to the blind by electrically stimulating the remaining neurons in the visual system. The ultimate goal of bionic eye research as a means of treating - vision loss is the capacity to reproduce the same neural messages that travel between the eye and the brain of normal vision. The visual system 'sees' the world by way of sending signals to the brain that indicate transitions from 'light ON to light - OFF' and from 'light OFF to light ON' wherever a transition exists. Despite the remarkable progress over the last decade, until recently, visual neuroprostheses could only stimulate both the ‘ON-to-OFF’ and the ‘OFF-to-ON’ pathways simultaneously, - sending confusing neural messages to the brain. Selective activation has been demonstrated in vitro while validated computational models predict that neural signals can be modulated by affecting these waveforms. This proposal aims to investigate, in - a functional model of the disease (Royal College of Surgeons rats), new ways to preferentially activate the aforementioned visual pathways using amplitude- and frequency- modulated signals combined with low-power noise. It is expected that the - resulting neural encoding to be more natural and to therefore improve the perception of the bionic eye recipients. Two strategies will be adopted: (1) acute electrophysiology experiments to obtain optimal stimulation parameters, and (2) chronic - studies in behaving animals with retinal degeneration subjected to classical conditioning. This is a highly multidisciplinary proposal that includes a comprehensive plan for the dissemination of the results among the scientific community and the - general public, while providing opportunities for industrial engagement. The fellow will be immersed in a motivating research environment and will be exposed to a series of training and networking activities which provide an excellent ground for - future career perspectives. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - NeuroBaBEL - - - H2020-MSCA-IF-2016 - - - 746526 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - DANFYSIK AS - ACADEMISCH ZIEKENHUIS LEIDEN - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - TESORO IMAGING SL - - - EUR 3 216 250 - - - IN SITU IMAGING OF LIVING TISSUES WITH CELLULAR SPATIAL RESOLUTION - - - EUR 3 216 250 - - - Spain - Denmark - Netherlands - Germany - Spain - - - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The main objective of HISTO-MRI project is to develop the technologies that will enable the non-invasive visualization of individual human cells in vivo and in real time, based on a radical new Magnetic Resonance Imaging - concept: High Frequency Pulsed MRI. To accomplish this ambitious objective, several new challenging multidisciplinary technologies will have to be developed: 1) new method for the production of magnet coils, based on additive manufacturing - technology, in order to stand very high currents at very high frequencies; 2) novel high frequency high voltage pulse power sources, based of semiconductor switches, to feed those magnet coils; and new pulse sequencing and computer algorithms to deal - with and analyse the enormous amount of data. Therefore, this project has a foundational character, establishing the basis for a new field of research, pulsed MRI in the high frequency regime, which will radically advance MRI performance to micron - resolution. - - 2019-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-01-2016-2017 - FET-Open research and innovation actions - - - RIA - Research and Innovation action - - - Spain - - - HISTO-MRI - - - H2020-FETOPEN-1-2016-2017 - - - 737180 - - - - - UNIVERSITAET STUTTGART - UNIVERSITAET STUTTGART - - - EUR 2 422 543 - - - Electric field imaging of single molecular charges by a quantum sensor - - - EUR 2 422 543 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Precision measurements are a key application of quantum technology. They have brought record precision in time measurement or outstanding sensitivity in measuring a whole wealth of quantities. Bringing such measurements to the - nanoscale is new. If those quantum sensor function under a variety of environments, including ambient or physiological condition they promise unprecedented application. - - - 2022-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - SMel - - - ERC-2016-ADG - - - 742610 - - - - - INSTITUT PASTEUR - UNIVERSITY OF GLASGOW - POLO D'INNOVAZIONE DI GENOMICA, GENETICA E BIOLOGIA SCARL - INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT - INSTITUT PASTEUR DE NOUVELLE-CALEDONIE - UNIVERZITA KARLOVA - CENTRE DE COOPERATION INTERNATIONALE EN RECHERCHE AGRONOMIQUE POUR LEDEVELOPPEMENT - C.I.R.A.D. EPIC - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - INSTITUT DE RECERCA I TECNOLOGIA AGROALIMENTARIES - EUROPEAN MOLECULAR BIOLOGY LABORATORY - THE PIRBRIGHT INSTITUTE LBG - CENTRO AGRICOLTURA E AMBIENTE GIORGIO NICOLI SRL - TROPIQ HEALTH SCIENCES - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - STICHTING KATHOLIEKE UNIVERSITEIT - Univerzitet u Novom Sadu, Poljoprivredni fakultet Novi Sad - UNIVERSITAT ZURICH - Liverpool School of Tropical Medicine - Institut Pasteur De Dakar - UNIVERSITE DES SCIENCES DES TECHNIQUES ET DES TECHNOLOGIES DE BAMAKO - Fondation Health Sciences e-Training - WAGENINGEN UNIVERSITY - MINISTERE DE LA SANTE - - - EUR 9 998 845,25 - - - Research Infrastructures for the control of vector-borne diseases - - - EUR 9 998 845,25 - - - France - United Kingdom - Italy - France - New Caledonia - Czech Republic - France - United Kingdom - Spain - Germany - United Kingdom - Italy - Netherlands - Germany - Greece - Netherlands - Serbia - Switzerland - United Kingdom - Senegal - Mali - Switzerland - Netherlands - Burkina Faso - - - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Other - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - The overall objective of the Infravec2 project is to integrate key specialized research facilities necessary for European excellence in insect vector biology, to open the infrastructure for European access, and to develop new - vector control measures targeting the greatest threats to human health and animal industries. Infravec2 is an Advanced Community, following a four-year Starting Community lifecycle (FP7 Infravec1). Lack of access to key infrastructures limits - European vector research and impedes development of vector control measures. Insect vectors transmit parasitic diseases such as malaria and leishmaniasis, and viral infections such as chikungunya, dengue, Zika, Japanese encephalitis and yellow fever. - Vector-borne diseases, which have historically been a problem of tropical countries, now represent a threat for temperate regions of the world including much of Europe. The 24 consortium partners, including 4 commercial companies, hold the major - European biosecure insectaries for experimental infection and containment of insect vectors under Containment Level 2 and 3 (CL2/CL3) conditions, other key insect vector facilities, and include front-line field sites in Africa, the Pacific, and the - Americas. Infravec2 will implement comparable standards across the secure insectary facilities as a world first, improving exploitation of European vector infrastructures for research and public health, and will develop other innovative methodologies - and technologies. Networking activities will assure that the project achieves full impact, producing a step change in European vector biology research and the product pipeline, and consolidating European global leadership in insect vectors. The goal - of the Infravec2 project is to build a durable European infrastructure to control insect vector-borne disease, including with power to predict and prevent the inevitable next epidemic outbreak in advance. - - 2021-01-31, ongoing project - - - 2017-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.1.2."> - - - INFRAIA-01-2016-2017 - Integrating Activities for Advanced Communities - - - RIA - Research and Innovation action - - - France - - - INFRAVEC2 - - - H2020-INFRAIA-2016-1 - - - 731060 - - - - - POLITECNICO DI MILANO - POLITECNICO DI MILANO - - - EUR 149 375 - - - A novel instrument to identify chiral molecules for pharmaceutics and bio-chemistry. - - - EUR 149 375 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This proposal aims at bringing to the market a revolutionary device to uniquely identify the chirality of molecules. An object is chiral if it differs from its mirror image, like our left and right hands. Chirality plays an - extremely important role in two main fields: (1) Many drugs are chiral and selecting one of the two forms often enables the pharma industry to extend patent franchise, thus increasing profitability, and to improve the quality, safety and efficacy of - the drug. (2) Researchers in the chemistry and biophysics labs use chirality as an indication of the 3D structural conformation of proteins and DNA, to study e.g. their secondary structure and stability under external stimuli. Spectrometers for - measuring chirality already exist in the market. Many customers in the two aforementioned sectors could be interested in the new product we propose because it presents several advantages, namely a 2-fold reduction of the price, a 4-fold shrinking of - the footprint and an increased information content. The ground-breaking concept (under patenting) behind this new spectrometer is to employ an ultra-stable interferometer to measure the chiral spectrum of molecules via a Fourier-transform approach - and a heterodyne amplification of the signal. A first working prototype has already been realized and tested. The CHIMERA project has two main goals. (1) We aim at unleashing the innovation potential of the approach, by technically validating two - prototypes in a pharmaceutical company and a biochemistry research lab, thus pushing the Technology Readiness Level of the system to the ultimate maturity required to approach the market, corresponding to TRL9. (2) We will design a complete - exploitation plan, performing a thorough analysis of the market, developing a financing strategy, benchmarking our instrument against the competitors’ ones, profiling strategic partners and drafting a first version of a Business Plan to decide on the - opportunity to found a start-up company. - - 2018-10-31, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Italy - - - CHIMERA - - - ERC-2016-PoC - - - 754802 - - - - - VYSOKE UCENI TECHNICKE V BRNE - VYSOKA SKOLA BANSKA - TECHNICKA UNIVERZITA OSTRAVA - CEMMAC AS - ZPSV, AS - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 558 000 - - - Utilization of secondary raw material in geopolymers production - - - EUR 558 000 - - - Czech Republic - Czech Republic - Slovakia - Czech Republic - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - - A lot of cement plants all around Europe are standing before problem of by-pass kiln dust disposal. Nowadays small part of production is added in stabilizing admixture and the rest is disposed of as a waste material. In light - of the fact that this material contains approximately 10–50 wt. % of KCl, free lime and dicalcium silicate, the possibility of their usage in alkali activated systems is at hand. - - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Czech Republic - - - GeoDust - - - H2020-MSCA-RISE-2016 - - - 734833 - - - - - THE UNIVERSITY OF WARWICK - - - EUR 195 454,80 - - - In situ stress analysis of lithium-ion battery cell - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Lithium-ion batteries (LIB) are found in many applications such as consumer electronics, electric vehicles and airplanes. However, despite of the high safety standards being imposed, there have been many reported accidents as - well as recalls by some manufacturers. Most accidents can be sourced to runaway reactions, which could happen if the LIBs are overheated or overcharged. Thermal runaway can cause rapid temperature rise in the LIB, resulting in excessive thermal - stress in the electrodes and the separator, a permeable membrane placed between the anode and cathode. Such mechanical degradation can cause the fading of battery capacity, and in extreme cases result in cell rupture, releasing of flammable gases, - fire and explosions. - - - 2020-07-29, Grant Agreement signed - - - 2018-07-30 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - LIB STRESS - - - H2020-MSCA-IF-2016 - - - 749512 - - - - - KOBENHAVNS UNIVERSITET - - - EUR 200 194,80 - - - Wealth, Virtue and Social Justice in Contemporary Tibet - - - EUR 200 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - This project examines the relationship between Buddhism and ideas about wealth, virtue and social justice in contemporary Tibet. The objectives are: a) to reveal central moral assumptions about value and the social good in a - ‘Buddhist’ society experiencing rapid development, rising consumption levels and growing inequalities; and b) to use these findings to engage with wider theoretical debates about value and exchange, commodity and gift, and religion and economy. The - relationship between Buddhism and economy remains an underdeveloped research area – indeed my project coincides with a drive at the University of Copenhagen’s Centre for Contemporary Buddhist Studies to address this gap. Although often imagined to be - antithetical to contemporary consumer society, Buddhism has historically been intertwined with the economy and monasteries were dominant political and economic institutions in Tibet. In recent years increasing wealth has been flowing to Tibetan - monasteries and monks in a hitherto unexamined variety of forms and modes, some of which have been the subject of moral reflection and critique. This upsurge in patronage has paralleled rising income and consumption levels, but also increasing - inequalities, resulting from processes of Chinese state-led development. Utilising a unique and extensive body of ethnographic materials that I have collected during long-term fieldwork in north-eastern Tibet, I will document and analyse a variety of - cases of patronage of Tibetan monastic Buddhism in their local contexts. Drawing for inspiration on the ‘moral turn’ in anthropology, my aim is to identify and analyse points of ethical reflection, tension and debate at the interface between Buddhism - and economy. My hypothesis is that this will reveal underlying ideas about value and the social good; and that this will in turn help us to revisit and reassess both our understanding of Buddhism and theories of exchange, value and consumption - dominated by economistic approaches. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - VIRTUE - - - H2020-MSCA-IF-2016 - - - 747673 - - - - - LUXEMBOURG INSTITUTE OF SCIENCE AND TECHNOLOGY - - - EUR 172 800 - - - Gestures in Tangible User Interfaces - - - EUR 172 800 - - - Luxembourg - - - Research Organisations - - GETUI investigates through user studies the use of gestures in interaction with Tangible User Interfaces (TUIs) in the context of technology-based assessment (TBA) of collaborative and complex problem solving skills. - Collaborative problem solving is defined as the capacity to recognise the perspective of other people in a group, participate, contribute knowledge, recognise the need for contributions and build knowledge and understanding as member on a - collaborative setting (Ras et al. 2013). Most of the research in TBA of collaborative problem solving skills dealt with the improvement of assessment of traditional skills. However, the focus should be on the so-called 21st Century skills: CPS, - creativity, critical thinking, learning to learn, decision-making. Ras et al. (2013) state that for many challenges in TBA, ICT are the solution to assess 21st Century skills, but also the problem, as scientific knowledge about how assessment models - need to be adapted as well as practical knowledge about how to create more authentic problem situations with future assessment tools are lacking. Until now there is no TUI that has been systematically used and evaluated in the context of TBA. - Moreover, in TBA, gestures on TUIs have not been yet explored. Thus not only is the research of TUI as an assessment construct a new research field, but also the dimension of gestures makes GETUI an innovative and timely project. This - interdisciplenary research will not only fill the gap of scientific knowledge, but will also have an impact at a European level creating new instruments for assessing 21st Century skills based on capturing behavioural indices of human-computer and - human-human interactions in collaborative TBA situations. - - 2017-10-31, closed project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - Luxembourg - - - GETUI - - - H2020-MSCA-IF-2014 - - - 654477 - - - - - COVENTRY UNIVERSITY - - - EUR 195 454,80 - - - SOLAR ADSORPTION REFRIGERATOR WITH THIN-LAYER/ENHAMCED ADSORBENT - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Increased energy costs, the uncertainty of fossil fuel availability, and climate change concerns, have necessitated the quest for renewable energy resources. Solar adsorption systems are quiet, simple to operate, and can last - for a long time. However, they have low cooling power density, and subsequently have to be bulky compared to similar solar thermal systems offering the same performance. This can increase their initial costs, especially for small and medium sized - systems, thus reducing their uptake. Currently researchers have successfully tackled this issue by, for instance, using more than one adsorbent bed to adopt a continuous cycle, and using forced cooling for the adsorber bed and condenser. These have - not resolved the bulk/cost issues, however. This innovative Fellowship will apply a thin layer nano-particles embedded adsorbent, nano-fluid based refrigerants and selectively absorbing solar plate collectors to the system. We will develop a robust - simulation model to help with the design process. The system will be partly built using a novel diffusion bonding process that enables dissimilar materials to be joined seamlessly. We will test the adsorption properties of the novel adsorbent - materials and apply them to the refrigerator. We aim to deliver a solar adsorption refrigerator that employs nano-technology and novel manufacturing methods, meets the performance improvements currently achievable but not with the bulk and - complexity. We expect scholars and industry to also apply the technology demonstrated to several other uses, and for them to be more accessible to the general public. The Fellow has all the necessary skills and experience required (including chemical - adsorption, thermodynamics, heat & mass transfer) while the host lab has all the infrastructure and experience of hosting researchers. The project is also timely as it fits into the EU Energy policy (ESTPP Vision 2030). - - 2018-03-31, Grant Agreement terminated - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SARTEA - - - H2020-MSCA-IF-2014 - - - 661515 - - - - - NATURAL ENVIRONMENT RESEARCH COUNCIL - - - EUR 183 454,80 - - - Peering through the East Antarctic Ice Sheet to reveal geology, crustal architecture and tectonic influences on ice sheet dynamics - - - EUR 183 454,80 - - - United Kingdom - - - Research Organisations - - Although East Antarctica is regarded as a keystone in the Rodinia and Gondwana supercontinents and is a pivotal component of the global climatic system it remains the least known continent on Earth. With REVEAL we aim to - unveil the crustal structure, tectonic architecture and evolution of several major frontier regions in East Antarctica. The project will also address large-scale geological controls on bedrock topography, subglacial hydrology and ice sheet dynamics. - Our models and interpretations of potential field data will enable us test several hypotheses regarding the effects of collision, accretion and rifting on East Antarctica. This has significant implications for comprehending the impact of - supercontinental assembly and break up on the structure and evolution of East Antarctica. Using state of the art three dimensional modelling, we will obtain an enhanced understanding of intraplate mountain building in the enigmatic Gamburtsev - Subglacial Mountains region. This is highly significant, as these mountains were critical for East Antarctic Ice Sheet development. The enhanced knowledge of subglacial geology that will derive from our analyses of the Recovery Frontier and Wilkes - Land will facilitate new assessments of the influence of geological boundary conditions on the dynamics and the stability of these potentially more vulnerable marine-based parts of the East Antarctic Ice Sheet. The REVEAL project has a strong - international dimension and will deliver several high-profile publications and dissemination activities. It will provide unique and timely training and career development opportunities for the experienced researcher. - - 2017-05-17, closed project | - - - 2015-05-18 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - REVEAL - - - H2020-MSCA-IF-2014 - - - 657187 - - - - - INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE - - - EUR 185 076 - - - High-throughput characterization of host promiscuity for precisely designed synthetic viral capsid - - - EUR 185 076 - - - France - - - Research Organisations - - Traditional geographic ranges of insect pests are altered by globalization and climate change, resulting in emerging threats for natural ecosystems, agriculture and human health. It is urgent to improve our ability to swiftly - develop targeted solutions to contain such threats, while minimizing unintended side effects on the environment. - - 2017-06-30, Grant Agreement terminated | - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - Hi-SynVir - - - H2020-MSCA-IF-2014 - - - 660212 - - - - - VALSTYBINIS MOKSLINIU TYRIMU INSTITUTAS FIZINIU IR TECHNOLOGIJOS MOKSLU CENTRAS - - - EUR 114 432,15 - - - Energy losses in nitride light-emitting diodes - - - EUR 114 432,15 - - - Lithuania - - - Research Organisations - - Light-emitting diodes (LEDs) are the future of lighting for general-purpose and industrial applications because of their potentially superior efficiencies. Group-III nitrides are the principal materials used to manufacture - blue and green LEDs. However, they are still rather inefficient, despite a lot of research efforts. Increasing the efficiency and reducing the cost of LEDs is currently the question of paramount importance. - - 2017-01-31, closed project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Lithuania - - - NITRIDE-SRH - - - H2020-MSCA-IF-2014 - - - 657054 - - - - - UNIVERSITEIT LEIDEN - UNIVERSITEIT LEIDEN - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - - - EUR 1 499 950 - - - Plant foods in human evolution: Factors affecting the harvest of nutrients from the floral environment - - - EUR 1 499 950 - - - Netherlands - Netherlands - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - - Plant foods comprise the majority of most human diets, yet the potential importance of these foods in human evolution is often overlooked. Using a behavioral ecology framework, the HARVEST project explores fundamental - questions: Why did hominins choose to eat certain plants? What were their foraging goals? We will focus on two objectives: 1) Reconstructing the diets of fossil hominins and 2) Exploring the costs and benefits of plant foods. - - 2022-01-31, ongoing project - - - 2017-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - HARVEST - - - ERC-2015-STG - - - 677576 - - - - - TECHNISCHE UNIVERSITEIT DELFT - - - EUR 165 598,80 - - - Bell Experiment on Quantum Optomechanical Microresonators - - - EUR 165 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Experimental demonstration of superposition states of massive systems, often referred to as Schrödinger cat states, has been an exciting research line of several fields in quantum physics. There have been many impressive - experiments with a variety of different systems over the past years and research along these lines is still highly popular. - - 2019-07-16, Grant Agreement terminated - - - 2017-07-17 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - BEQOM - - - H2020-MSCA-IF-2016 - - - 740475 - - - - - HELSINGIN YLIOPISTO - - - EUR 191 325,60 - - - Biodiversity drivers on islands and continents - - - EUR 191 325,60 - - - Finland - - - Higher or Secondary Education Establishments - - Why do some regions encompass higher number of species? Which are the main drivers of biodiversity in different biogeographical areas and ecosystems? Many efforts have been made to decipher the main factors that play a key - role in the patterns and processes that generate biodiversity and contribute to the structuring of communities at different spatial scales. Through a multidisciplinary approach, this project aims to shed light into the biogeographical and - evolutionary processes that generate biodiversity, using multiple island and continent datasets to compare diversity drivers between model systems where distinct processes have shaped the current species composition. The feasibility of BIODIV - ISLAND-CONT is supported by the extensive database provided by four different European funded projects, offering an invaluable tool to study the differences in community assembly of islands vs. continents. The project will be hosted by two - high-quality European institutions: FMNH-UH in Finland and IPNA-CSIC in Spain, enhancing the reciprocal transfer of knowledge among different European partners. Overall, the goals proposed in this project will allow testing general macroevolutionary - hypotheses of broad interest to the scientific community. - - 2018-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Finland - - - BIODIV ISLAND-CONT - - - H2020-MSCA-IF-2015 - - - 706482 - - - - - THE UNIVERSITY OF BIRMINGHAM - - - EUR 195 454,80 - - - Roma, Gypsies and Travellers' social in/exclusion in European urban camps - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The project aims to analyse the role of Civil Society Organisations (CSOs) in Roma, Gypsies and Travellers’ (RGTs) in/exclusion in European urban camps. Triangulating individual semi-structured interviews, oral histories, - archival research, and interpretative policy analysis, the interdisciplinary project combines Sociological, Socio-Anthropological and Socio-Historical approaches, contemplating two UK and two Italian superdiverse urban contexts as case studies. It - contributes to three research streams: housing exclusion; RGT policy, and camps as socio-spatial configurations, and inaugurates a new interdisciplinary research field on Urban Camps. Dr Sigona, who will act as the Supervisor, is a leading scholar in - migration and Roma research in Europe; his expertise is particularly complementary with Dr Picker research skills and knowledge coming from ten years of Sociological field-based research on Roma spatial segregation in five European countries. Due to - the excellent quality of infrastructure, scholarly research and staff, the School of Social Policy and the Institute for Research into Superdiversity at the University of Birmingham are the most appropriate academic environment for Dr Picker to - become, after the Fellowship, a leading social science scholar in the European Research Area. - - 2018-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - CAMP-BIVALENCE - - - H2020-MSCA-IF-2014 - - - 661646 - - - - - HASKOLI ISLANDS - HASKOLI ISLANDS - - - EUR 150 000 - - - Developing Novel and Optimal Additive Solutions for Red Blood Cells - - - EUR 150 000 - - - Iceland - Iceland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The research conducted in SYSTEM_US (ERC Advanced Grant #232816) has led to the discovery of valuable biomarkers for the quality of red blood cells (RBCs) in standard blood bank storage conditions. Using a combination of - systems biology and metabolomics, this discovery will lead to the development of novel RBC storage technologies including additive solutions and diagnostics. These technologies will become valuable assets in the form of intellectual property to large - transfusion medicine companies and will save thousands of lives over the coming decades. This proposal covers the needs to fully define the market and NPV of the developing technology, fully define the regulatory and clinical path of product - approval, file for patents to protect the intellectual property, conduct necessary validation experiments, and continue to develop relations with industry contacts. - - 2016-08-31, closed project - - - 2015-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2014 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Iceland - - - DENOVO-RBC - - - ERC-2014-PoC - - - 641093 - - - - - INSTYTUT CHEMII FIZYCZNEJ POLSKIEJ AKADEMII NAUK - UNIVERSITAET REGENSBURG - TEL AVIV UNIVERSITY - - - EUR 688 500 - - - Metallocomplexes of macrocyclic compounds for photonic devices - - - EUR 688 500 - - - Poland - Germany - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The key objective of the METCOPH multidisciplinary project is to intensify and consolidate cooperation between several research groups from member states and third countries on topics within the field of fundamental - interdisciplinary science. The project combines the basic ideas of organic chemistry, solid state physics, photochemistry and spectroscopy of metallocomplexes of macrocyclic compounds (MMC) for applications in quantum information processing, sensing, - switching and amplification. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Poland - - - METCOPH - - - H2020-MSCA-RISE-2014 - - - 645628 - - - - - UNIVERSITA DEGLI STUDI DI MILANO - - - EUR 180 277,20 - - - Breaking frontiers in plant reproduction: understanding the roles of AGPs and epigenetics regulating male-female crosstalk towards fertilization - - - EUR 180 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - “By 2050 the Earth will need to feed two billion more people. How can we achieve that without overwhelming the planet?” The question, raised back in 2009, demands quick action. Human life depends on plants, which feeds us, our - livestock or fulfils our biofuel needs. Thus to feed this growing population, it will be necessary to double agricultural yields without increasing the amount of arable land. A fine knowledge of the fundamental molecular processes that finely - regulate plant reproduction, will allow increasing crop productivity and high quality seed production in a sustainable manner by agricultural engineering, safeguarding the increase of arable land usage. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - EpiAGPs - - - H2020-MSCA-IF-2016 - - - 753328 - - - - - UNIVERSITY COLLEGE LONDON - - - EUR 195 454,80 - - - REGionalism And INstututional dynamics in the EU - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The research project aims to investigate the formation of non-standard regions and the activation of multi-level governance practices induced by EU-led territorial cooperation instruments. It identifies four types of - non-standard regions (micro, cross-border, off-shore and macro) that correspond to 4 EU instruments (CLLD, EGTC, maritime spatial planning, and Macro-regional strategy). They constitute a programmatic domain in which the EU is advocating a new - regionalism agenda, which is based on the construction of new territorialised polities engaged in regional development and planning actions beyond formal administrative boundaries, from municipal to national ones. These new regional polities present - an extensive variety of socio-institutional dynamics, committed to thematic or political objectives, and policy delivery channels. The scope of the project is to evaluate whether the tailoring of these regional polities contribute to address more - appropriately socio-ecological regions, to activate cultural-cognitive understanding of new functional territories, to conceive more efficient spatial planning and development strategies. The project investigates one case-study region per each - instrument, with a primary attention to two areas: a new micro-region and a cross-border region, which will be evaluated in relation to their overlapping/interaction with off-shore and macro-regions. Moreover, the fellowship poses the basis for a - cutting-edge research program that explores the socio-cultural, political and institutional construction of these new territorialised polities; investigates their socio-institutional efficiency; makes explicit the characteristics of a renewed EU-led - regionalism agenda; and clarifies the limits and the opportunities that a regionalism agenda on non-standard region has in addressing the challenges of contemporary Europe and its regional dynamics. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - REGAIN - - - H2020-MSCA-IF-2016 - - - 749899 - - - - - UNIVERSITA DEGLI STUDI DI MILANO - - - EUR 180 277,20 - - - Direct reprogramming for HD Disease Modelling - - - EUR 180 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - Huntington’s disease (HD) is a rare and devastating autosomal dominantly inherited disorder caused by the amplification of the CAG codon in the huntingtin gene. The clinical symptoms of HD are chorea and motor incoordination - as well as psychiatric symptoms. To date no cure has been found to alter the progression of the striatal atrophy due to the dramatic loss of GABAergic medium spiny neurons (MSNs) which eventually leads to death. Over the past years increasing - knowledge around the function of huntingtin (HTT) has allowed the identification of number pathogenic mechanisms, however the specific processes whereby the mutated HTT leads to degeneration and their temporal evolution remains unknown. We believe it - is of vital importance to develop disease-relevant human cell models from clinically characterized HD subjects in which to address questions related to pathogenic mechanisms and their dependence on the CAG repeats. For this reason the aim of the - proposed project is to generate induced medium spiny neurons (iMSNs) from healthy or HD-diseased fibroblasts in order to generate a reliable disease modelling tool. The applicant will optimize an existing protocol for the generation of iMSNs from - direct conversion of fibroblasts published by Victor et al (2014) to obtain healthy iMSNs in the laboratory of prof. Elena Cattaneo at the University of Milan. In a second step she will perform direct in vitro reprogramming of human fibroblasts - derived from well characterized patients affected with HD exhibiting different degrees of CAG repeat expansion into induced HD-derived MSNs (HD-iMSNs). Finally, the newly generated HD-iMSNs will be analyzed, and their characteristics compared to - those of the healthy iMSNs, in order to assess their appropriatness as a disease modelling tool to investigate the pathophysiology and pathogenesis of HD. - - 2019-05-14, ongoing project - - - 2017-05-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - DISMOD-HD - - - H2020-MSCA-IF-2016 - - - 753077 - - - - - MEDICAL RESEARCH COUNCIL - - - EUR 183 454,80 - - - The role of OTULIN and Met1-linked ubiquitin in immune signaling and host defense in vivo - - - EUR 183 454,80 - - - United Kingdom - - - Research Organisations - - The immune system is essential for host defense against infections. Methionine1-linked ‘linear’ ubiquitin chains (Met1-Ub) have emerged as a crucial activator of NF-κB transcription factors, which are vital to immune - responses. Recent findings suggest that defects in Met1-Ub signaling in humans can lead to severe immune dysfunction and cancer. Met1-Ub is generated by the linear ubiquitin chain assembly complex (LUBAC). Yet, how LUBAC and Met1-Ub signaling are - regulated remains elusive. We recently discovered OTULIN, the only deubiquitinase known to specifically disassemble Met1-Ub. OTULIN antagonizes LUBAC and restricts Met1-Ub and NF-κB signaling in cell culture; however, the role of OTULIN and Met1-Ub - in immune signaling and host defense in vivo is largely unknown. We have established novel mouse strains with cell type-specific deletion of OTULIN. I will use these mice to explore the in vivo function of OTULIN and Met1-Ub in the innate and - adaptive immune responses, and to identify OTULIN substrates in primary cells using state-of-the-art mass spectrometry-based proteomics. I will study OTULIN’s role in immune homeostasis, in response to bacterial infection, and in mounting type-1 and - type-2 adaptive immune responses by state-of-the-art methods of immunological analyses including comprehensive multiplex analyses of cytokines. Met1-Ub regulates the acute phase cytokines TNF and IL-6 and may thus control the development of type-1 - versus type-2 immune responses. Hence, I will test OTULIN’s role in models of asthma, a disorder characterized by an imbalance between type-1 and type-2 responses. Subsequently, I will analyze immune signaling pathways in primary cells using mass - spectrometry-based proteomics to identify OTULIN substrates in specific cell types. This will greatly deepen our understanding of the physiological role of OTULIN and Met1-Ub in the immune response and may provide important insight into human - immunological disorders and rationales to treat these. - - 2017-03-31, closed project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - OTULINVIVO - - - H2020-MSCA-IF-2014 - - - 654019 - - - - - BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION - - - EUR 1 416 000 - - - SupercompuTing And Related applicationS Fellows Program - - - EUR 2 832 000 - - - Spain - - - Research Organisations - - The BSC STARS (SupercompuTing And Related applicationS) International Research Fellows program aims at fostering the training of highly skilled post-doc in all fields of High Performance Computing and related applications, - specifically in Earth Science and Meteorology, in Life Sciences, Genomics and Personalised Medicine and in Computational Engineering and Physics and Computational Societies, providing them with all the necessary tools for developing their potentials, - deepening their skills and knowledge in a stimulating, international and interdisciplinary environment, offering them intersectorial secondments with private industry or non-academic Research centers, in order to boost their career perspectives as - successful independent researchers. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2016 - Co-funding of regional, national and international programmes - - - MSCA-COFUND-FP - Fellowship programmes - - - Spain - - - STARS - - - H2020-MSCA-COFUND-2016 - - - 754433 - - - - - GEANT LIMITED - GEANT VERENIGING - UNIVERSITAT WIEN - UNIVERZITET U BEOGRADU - AKADEMSKA RAZISKOVALNA MREZA SLOVENIJE - INSTITUTE FOR INFORMATICS AND AUTOMATION PROBLEMS OF THE NATIONAL ACADEMY OF SCIENCES OF THE REPUBLIC OF ARMENIA - UNITED INSTITUTE OF INFORMATICS PROBLEMS OF NATIONAL ACADEMY OF SCIENCES OF BELARUS - BELNET - BULGARIAN RESEARCH AND EDUCATION NETWORK - HRVATSKA AKADEMSKA I ISTRAZIVACKA MREZA CARNET - CESNET ZAJMOVE SDRUZENI PRAVNICKYCH OSOB - ΚΥΠΡΙΑΚΟ ΕΡΕΥΝΗΤΙΚΟ ΚΑΙ ΑΚΑΔΗΜΑΪΚΟ ΔΙΚΤΥΟ (KYPRIAKO EREVNITIKO KAI AKADIMAIKO DIKTYO) - VEREIN ZUR FOERDERUNG EINES DEUTSCHEN FORSCHUNGSNETZES DFN VEREIN E.V. - FUNDACAO PARA A CIENCIA E A TECNOLOGIA - CONSORTIUM GARR - GEORGIAN RESEARCH AND EDUCATIONAL NETWORKING ASSOCIATION - ETHNIKO DIKTYO EREVNAS TECHNOLOGIAS AE - HEANET LTD - Hariduse Infotehnoloogia Sihtasutus - MACHBA - INTERUNIVERSITY COMPUTATION CENTER - JISC COLLECTIONS AND JANET LIMITEDLBG - KAUNO TECHNOLOGIJOS UNIVERSITETAS - MACEDONIAN ACADEMIC AND RESEARCH NETWORK SKOPJE - JAVNA USTANOVA UNIVERZITET CRNE GORE PODGORICA - KORMANYZATI INFORMATIKAI FEJLESZTESI UGYNOKSEG - NEMZETI INFORMACIOS INFRASTRUKTURA FEJLESZTESI IRODA - NORDUNET A/S - INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK - ENTIDAD PUBLICA EMPRESARIAL RED.ES - RESEARCH AND EDUCATIONAL NETWORKING ASSOCIATION OF MOLDOVA - GROUPEMENT D INTERET PUBLIC POUR LERESEAU NATIONAL DE TELECOMMUNICATIONS POUR LA TECHNOLOGIE L ENSEIGNEMENT ET LA RECHERCHE - Fondation RESTENA - Agentia de Administrare a Retelei Nationale de Informatica Pentru Educatie si Cercetare - ZDRUZENIE POUZIVATELOV SLOVENSKEJAKADEMICKEJ DATOVEJ SIETE-SANET - SURFnet bv - SWITCH - TURKIYE BILIMSEL VE TEKNOLOJIK ARASTIRMA KURUMU - UNIVERSITA TA MALTA - ASSOCIATION OF USERS OF UKRAINIAN RESEARCH AND ACADEMIC NETWORK URAN - LATVIJAS UNIVERSITATES MATEMATIKAS UN INFORMATIKAS INSTITUTS - - - EUR 59 000 000 - - - GN4-2 Research and Education Networking - GÉANT - - - EUR 95 904 005,75 - - - United Kingdom - Netherlands - Austria - Serbia - Slovenia - Armenia - Belarus - Belgium - Bulgaria - Croatia - Czech Republic - Cyprus - Germany - Portugal - Italy - Georgia - Greece - Ireland - Estonia - Israel - United Kingdom - Lithuania - Former Yugoslav Republic of Macedonia - Montenegro - Hungary - Hungary - Denmark - Poland - Spain - Moldova - France - Luxembourg - Romania - Slovakia - Netherlands - Switzerland - Turkey - Malta - Ukraine - Latvia - - - Other - Other - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Research Organisations - Research Organisations - Other - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Other - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Other - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Other - Research Organisations - Higher or Secondary Education Establishments - Other - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Research Organisations - Research Organisations - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - - GN4-2 is the proposed project for the second Specific Grant Agreement under the 68-month Framework Partnership Agreement (FPA) established between the GÉANT Consortium and the European Commission in April 2015.This second - phase of implementing the FPA will raise European research to the next level by promoting scientific excellence, access and re-use of research data. It will also drive European-wide cost efficiencies in scientific infrastructure by promoting - interoperability with other e-infrastructures on an unprecedented scale. - - 2018-12-31, ongoing project | - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4."> - - - GEANT-2016 - Research and Education Networking – GÉANT - - - SGA-RIA - SGA-RIA - - - United Kingdom - - - GN4-2 - - - H2020-IBA-SGA-INFRA-GEANT-2016 - - - 731122 - - - - - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - - - EUR 183 454,80 - - - Transmission of Financial Shocks:A systemic Input-Output GVAR approach - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Over the past years, the economic and financial systems have become increasingly globalized and vulnerable with important implications for risk management by commercial banks and other institutions. However, despite the fact - that sophisticated models for quantifying credit risk have been developed, everyday practice has shown that risk, due to its inherent role in the economic system, is affected by both: (i) macroeconomic factors and (ii) financial factors. Hence, it - would be extremely beneficial to generate scenario analyses, real-time simulations and forecasts based on a core set of variables. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - Shocks Transmission - - - H2020-MSCA-IF-2016 - - - 749161 - - - - - INSTYTUT MATEMATYCZNY POLSKIEJ AKADEMII NAUK. - UNIWERSYTET WARSZAWSKI - UNIWERSYTET LODZKI - UNIVERSITY OF GLASGOW - THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN - KOBENHAVNS UNIVERSITET - WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER - VRIJE UNIVERSITEIT BRUSSEL - SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI DI TRIESTE - - - EUR 288 000 - - - New Geometry of Quantum Dynamics - - - EUR 288 000 - - - Poland - Poland - Poland - United Kingdom - United Kingdom - Denmark - Germany - Belgium - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The Project aims to make significant advances to the field of noncommutative geometry by developing new methods through substantial interaction within sub-fields of noncommutative geometry and two other areas of pure - mathematics. The main focus will be to determine the topological non-triviality of new types of quantum fibrations. Also, we aim to construct quantum metric geometries of crossed products and graph algebras relating the Lipschitz-norm and - Dirac-operator approaches. The Project will combine various areas, which although interacting on the fundamental level, have had their concrete and usable connections mostly unexplored. - - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Poland - - - QUANTUM DYNAMICS - - - H2020-MSCA-RISE-2015 - - - 691246 - - - - - DEUTSCHES INSTITUT FUR INTERNATIONALE PADAGOGISCHE FORSCHUNG - - - EUR 171 460,80 - - - Processes and Outcomes of Educational Evaluation from a Cross-Cultural Perspective - - - EUR 171 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - The full complexity of educational evaluation at various levels (i.e., system, school, classroom, and student) in different countries has hardly been recognized. It constitutes a tremendous barrier to consolidate theories on - evaluation, and for countries to draw on successful experience and implement targeted educational policies for better quality and effectiveness. Important barriers include the insufficient methodology to soundly compare multiple countries and a - cultural insensitive approach to unfolding evaluation processes and outcomes. This project aims to provide a comprehensive framework for the dynamics of evaluation with a solid cross-cultural research methodology. Using self-report data in 70 - countries/economies in the 2015 Programme for International Student Assessment (PISA), this project delineates the pathways in processes and outcomes of educational evaluation in 70 educational systems by integrating policies at system level, - practices in schools and classrooms, and student assessment outcomes with demonstrated comparability of data. Study 1 has a methodological focus to analyze scalable measures and their cross-cultural comparability. It tests whether self-report - multiple-item measures from school principals, teachers, and students across countries reach approximate measurement invariance to ensure proper comparisons. Study 2 tests the effects of accountability policy, country affluence at country-level, and - various evaluation practices including the feedback mechanisms at school and teacher levels, and the cross-level interactions on a broad range of student outcomes such as achievement, motivation, wellbeing, and test anxiety. This project contributes - to theory building on educational evaluation from a cross-cultural perspective and identify effective measures for more targeted educational interventions. - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - POEECCP - - - H2020-MSCA-IF-2016 - - - 748788 - - - - - UNIVERSITE PARIS-SUD - - - EUR 173 076 - - - Novel 3D nano-antennas for optoelectronic applications in the mid-infrared - - - EUR 173 076 - - - France - - - Higher or Secondary Education Establishments - - This research proposal aims at implementing novel functionalities for mid-infrared optoelectronic devices and to study novel physical phenomena, enabled by a new class of 3D plasmonic nanostructures that provide access to - electromagnetic field confinements. - - 2020-03-31, Grant Agreement signed - - - 2018-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - NANO-MIR - - - H2020-MSCA-IF-2016 - - - 748071 - - - - - UNIVERSIDAD DE CORDOBA - - - EUR 257 191,20 - - - Understanding Non-Photochemical Quenching Regulation in a Dynamic Environment. - - - EUR 257 191,20 - - - Spain - - - Higher or Secondary Education Establishments - - Life on Earth relies on photosynthesis that converts water and carbon dioxide into organic molecules using absorbed light by chlorophylls bound to light harvesting complexes (LHC). During evolution, LHC have maximized the - capability to capture light energy, allowing organisms to grow even in very low light environments. However, during nutrient deprivation or under high light conditions, when light absorption exceeds the capacity for carbon dioxide fixation, the - excess absorbed energy can elicit the generation of reactive oxygen species that cause severe oxidative damage. Photosynthetic organisms have developed mechanisms of non-photochemical quenching (NPQ) that alleviate this photo-oxidative stress in the - timescale of seconds to minutes. This NPQ is critical to protect the integrity of the photosynthetic apparatus, allowing the organisms to survive in a dynamic light and nutrient environment. In algae, LHCSR (LHC Stress Related) proteins catalyze NPQ, - but their specific role and regulation are poorly understood. For this project, I will use the model organism Chlamydomonas reinhardtii in which two LHCSR proteins have been identified. My main goals will be (1) to characterize components involved in - NPQ under conditions experienced in nature, where light intensities vary and nutrient conditions (C, N and S) are suboptimal, and (2) to explore regulatory circuits and signaling molecules that impact NPQ. The experimental approaches involve - characterization of novel mutant strains unable to properly trigger NPQ, transcriptomic analysis to elucidate the effect of NPQ deficit on global gene expression and pharmacological approaches to explore the impact of different signaling molecules in - NPQ. Understanding NPQ is essential to predict how photosynthetic organisms will behave with changes in atmospheric dioxide fixation levels, temperature and nutrient availability, but will also impact strategies for improving photosynthetic - efficiency and tolerance to harsh conditions. - - 2021-01-14, ongoing project - - - 2018-01-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Spain - - - UNREDE - - - H2020-MSCA-IF-2016 - - - 751039 - - - - - Eidgenössische Technische Hochschule Zürich - - - EUR 175 419,60 - - - Topological states with Spin-Dependent potentials for ultracold lithium - - - EUR 175 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - The recent understanding of the topological properties of matter has led to the search for the experimental production and control of topological excitations such as Majorana fermions. They appear at the boundary between a - topological superconductor and a normal metal and have intriguing properties such as non-abelian exchange statistics and insensitivity to decoherence. Their production would give an invaluable insight on the properties of topological phases of matter - as well as paving the way towards fault-tolerant quantum computing. The aim of this action is to create them in an ultracold atom set-up which is a ideal platform to engineer interesting Hamiltonians. - - 2020-06-30, Grant Agreement signed - - - 2018-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - TopSpiD - - - H2020-MSCA-IF-2016 - - - 746150 - - - - - REGION HOVEDSTADEN - - - EUR 200 194,80 - - - Statistical Modelling for relating multimodal neuroimaging to clinical outcomes in order to predict patient response to depression therapy. - - - EUR 200 194,80 - - - Denmark - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Every year, 1 out of 15 Europeans suffer from major depression (MDD) and MDD is the third cause of Disability-adjusted life-years. Today, the available treatments are clearly insufficient; only about 50% of MDD patients - respond to drug intervention. We here posit that identification of biomarkers that can predict treatment response is needed to adapt a personalized medicine approach, and most likely this will involve not a single outcome but a combination of - multimodal brain imaging outcomes, psychological, genetic, and environmental data. The complexity of such data requires a complex statistical model that currently does not exist. Thus, my aim is to develop a new flexible statistical method that can - take into account heterogeneous types of data. More specifically, I will develop a fully flexible Latent Variable Model (LVM) that can deal with high dimensional measurements (e.g. images), non-Gaussian variables, and non-linear relationships. I will - apply this flexible LVM on existing data from depressed and healthy individuals and later expand the application to predict treatment outcomes. The latter data are currently acquired and includes a cohort of MDD patients treated with a selective - serotonin reuptake inhibitor (SSRI), followed in a longitudinal design. The chosen host institution is perfectly situated to this project, as they have an established unique database including, e.g., functional Magnetic Resonance Imaging (fMRI), high - resolution Positron Emission Tomography (PET), and neuropsychological test outcomes. This research project uniquely combines advanced statistical modelling of rich data sets with the ultimate aim to establish individualized depression therapy. - Moreover, it forms a foundation for a more general approach to integrate brain neurobiology in terms of imaging outcomes with other patient-specific data. - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - NEUROMODEL - - - H2020-MSCA-IF-2016 - - - 746850 - - - - - UNIVERSITY COLLEGE LONDON - - - EUR 276 107,40 - - - Resilience, Mindfulness and Medication Safety with Electronic Systems - - - EUR 276 107,40 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Medications are one of the most common healthcare interventions and one with great risk of adverse events and serious harm to patients. Medications incidents in hospitals are frequent and a serious concern. Electronic medicine - management systems (EMMS) implemented in hospital are known to reduce some safety risks but also introduce new ones. A way to prevent harm to patients from the use of medication is through organising for collective mindfulness (alertness to risks) - and through learning from everyday resilience. EMMS introduced in sociotechnical contexts of hospital care may affect collective mindfulness and resilience, in ways that are context (or nation) specific, as countries differ in structures, processes, - and legislation. - - 2020-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - MindSElS - - - H2020-MSCA-IF-2016 - - - 740131 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 170 121,60 - - - Unwanted catches of trawl fisheries: ecosystem effects and advances to an integratedmanagement approach in the Mediterranean - - - EUR 170 121,60 - - - Spain - - - Research Organisations - - There is an urgent need to address the environmental effects of fishing in order to maintain healthy marine ecosystems that provide the services societies want and need. This problem is addressed in the new Common Fisheries - Policy by encouraging the adoption of an Ecosystem Approach to Fisheries, including as a matter of priority the reduction of unwanted catches. In line with this policy, the project aims to address the ecosystem effects of commercial trawling, - including the unwanted catches problem, and generate knowledge that will contribute to the adoption of EAF. The project is structured in several inter-disciplinar activities, starting with gathering existing information on fishing effort, catches, - benthic species and habitats from trawling grounds in the NW Mediterranean. The information will be analysed to assess the vulnerability of by-catch species to trawling, and the Good Environmental Status of benthic ecosystems. The novelty of the - research approach will be increased by the adoption of a social-ecological framework. Interviews with the principal stakeholders will aim to assess their perception on the services provided by ecosystems from trawling grounds, and identify priority - areas for fisheries and for conservation. The vulnerability, GES and ecosystem services valorisation will be used to propose scenarios of alternative fishing strategies that minimise the negative effects on ecosystems, while taking into account - societal priorities. Then, size-spectra mathematical models will be explored to assess the ecosystem response to the different scenarios, aiming to identify the optimal management alternatives. The project structure will follow the principles of a - participatory approach, by taking into account fishermen’ perceptions on potential management alternatives, which will allow exploring real-world scenarios. - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Spain - - - FishMan - - - H2020-MSCA-IF-2016 - - - 743545 - - - - - QUEEN MARY UNIVERSITY OF LONDON - - - EUR 183 454,80 - - - The Internet of Musical Things - An ecosystem of interoperable devices connecting performers and audiences - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - This project aims at designing, developing, and validating new interfaces for technologically-mediated interaction between performers and audiences in order to achieve novel forms of musical expression and foster audience - engagement in live performing arts. Current systems for networked music performances that allow performers to collaboratively create music over a network), and for participatory live music performance that enable audiences to actively engage in the - music creation process, are limited both from the technological and artistic perspectives. To progress the state-of-the-art, we propose to extend the concepts of the Internet of Things to the musical domain leading to a subfield that we coin as the - Internet of Musical Things (IoMUT). IoMUT refers to the network of physical objects (Musical Things) dedicated to the production and fruition of multimodal musical content. This project will implement the IoMUT by creating Musical Things in the form - of new musical instruments and new wearable devices, and by delivering a technological infrastructure that allows for their bidirectional wireless communication, both locally and remotely. Such an infrastructure will enable an ecosystem of - interoperable devices connecting performers as well as performers and audiences to support new performer-performer and audience-performers interactions, not possible beforehand. The project will define and implement some use cases demonstrating the - proposed IoMUT and evaluate them. This approach aspires to effect a step-change in the design of interfaces for musical expression, resulting in a potentially high economic impact on the whole music industry. The project also contributes to the - fundamental understanding of the mechanisms underlying music perception and music performance in interactive and multimodal contexts. - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - IoMUT - - - H2020-MSCA-IF-2016 - - - 749561 - - - - - UNIVERSITY OF LEEDS - - - EUR 269 857,80 - - - Voltage Control of Chiral Spin Structures - - - EUR 269 857,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - This project will develop a new way to manipulate chiral spin structures such as skyrmions using voltages. Building on the expertise of the fellow in voltage control of magnetism in multiferroic heterostructures, this project - uses the unique Spin-Polarised Low Energy Electron Microscope (SPLEEM, in Berkeley) to characterize chiral spin structures in tailored multiferroic heterostructures. By studying (in Leeds) the effects of voltage control on current-driven skyrmion - motion in these heterostructures, V-ChiralSpin aims to establish a new, technologically relevant, research area. - - 2021-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - V-ChiralSpin - - - H2020-MSCA-IF-2016 - - - 750147 - - - - - KATHOLIEKE UNIVERSITEIT LEUVEN - DANMARKS TEKNISKE UNIVERSITET - UNIVERSITA DEGLI STUDI DI PADOVA - KARLSRUHER INSTITUT FUER TECHNOLOGIE - TECHNISCHE UNIVERSITEIT DELFT - THE UNIVERSITY OF NOTTINGHAM - LAYERWISE - NUOVO PIGNONE SRL - ALICONA IMAGING GMBH - LEGO SYSTEM AS - - - EUR 3 944 925,36 - - - Precision Additive Metal Manufacturing - - - EUR 3 944 925,36 - - - Belgium - Denmark - Italy - Germany - Netherlands - United Kingdom - Belgium - Italy - Austria - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Additive Manufacturing (AM) is a fast−growing sector with the ability to evoke a revolution in manufacturing due to its almost unlimited design freedom and its capability to produce personalised parts locally and with - efficient material use. AM companies however still face technological challenges such as limited precision due to shrinkage and build−in stresses and limited process stability and robustness. Moreover often post−processing is needed due to the high - roughness and remaining porosity. In addition qualified, trained personnel is hard to find. This ITN project will address both the technological and people challenges. - - 2020-11-30, ongoing project - - - 2016-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Belgium - - - PAM^2 - - - H2020-MSCA-ITN-2016 - - - 721383 - - - - - FUNDACIO INSTITUT DE CIENCIES FOTONIQUES - - - EUR 158 121,60 - - - Optical valley Hall effect in gapped graphene for infrared and terahertz light photodetection - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - Modern information processing is based on the degrees of freedom (DOF) of electrons, which are known as charge and spin. Manipulating DOF of electrons is the core function of information-processing unit such as transistor and - photodetector. Finding and manipulating new DOF for electrons may open up possibility for next-generation information processing, such as quantum computing. Recently, a new DOF of electrons—valley pseudospin—was found in two dimensional (2D) - hexagonal lattices, whose band structures manifest a pair of valleys at the corner of the hexagonal Brillouin zone (labeled as K and -K valley), giving rise to a valley DOF that is in close analogy to electron spin. As 2D hexagonal crystal, graphene, - with ultrahigh carrier mobility and ultrafast optoelectronic signal processing ability, has great potential as carrier of valley DOF and intriguing prospect for both fundamental research and practical application of valleytronics. Therefore - manipulating valley pseudospin of electrons in graphene would greatly advance the study of valleytronics. This proposal presents the first experimental study of Berry optoelectronics in gapped graphene, in particular extremely strong Valley Hall - effects and Valley Hall dynamics. The implementation includes three sections. The first is to break inversion symmetry of graphene crystal by fabricating graphene/boron nitride heterostructure and dual-gate bilayer graphene device. This symmetry - breaking allows the Bloch electrons in K and -K valleys to experience valley-contrasted orbital magnetic moments and Berry curvatures, which result in valley-dependent optical selection rule and valley Hall effect. This supplies us paradigm for - infrared and terahertz photodetection for section two. In section three, we explore the dynamics of confining charge carriers in a specified valley, by measuring the time-resolved behaviors. - - 2019-08-21, ongoing project - - - 2017-08-22 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - VHPC - - - H2020-MSCA-IF-2016 - - - 747927 - - - - - FUNDACIO INSTITUT DE CIENCIES FOTONIQUES - - - EUR 158 121,60 - - - Environmental friendly narrow band-gap colloidal nanocrystals for optoelectronic devices - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - In recent years a widespread investigation of semiconductor materials and its use in optoelectronic devices has taken place. Despite the vast variety of semiconductor materials, solution processable semiconductor nanocrystals - (NC’s) take lead thanks to their excellent optoelectronic properties (tunable band-gap, high PLQY and optical stability) while they become more and more appealing for their low production cost. Although, a variety of semiconductor NC’s have been - synthesized for application in the visible spectral region, only few examples exist with tunability in mid and near-IR, and most notable high toxicity mercury and lead based NCs. On the other hand, nowadays we experience a burst of emerging near and - mid-IR technologies (e.g. solar cells, detectors, night cameras) which are moving towards the use of environmentally friendly IR emitting materials for large scale production. Therefore, NAROBAND aims to exploit the synthesis and the - functionalization of low-toxic narrow-band gap Ag2SxSey NC’s via both chemical and physical routes towards the fabrication of environmental friendly, low cost solar cell devices. The project focus on achieving full control of the bandgap - (1.2eV–0.4eV) via quantum confinement and stoichiometry allowing to decouple nanocrystals size and surface effects from bandgap, leading to a better control of the optoelectronic properties. Moreover, throughout careful surface characterization and - functionalization NAROBAND aims to suppression of the trap state density, enhancing the carrier mobility and manipulating the energy levels of the valence and conduction band of the NC’s. These material advancements will pave the way towards, - firstly, the fabrication of high efficient IR solar cell devices and later on the realization of tandem solar cell by using the conventional Si technology to harvest the high energy electromagnetic radiation of the sun, while the aforementioned solar - cell device will collect the, so far wasted, IR radiation. - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - NAROBAND - - - H2020-MSCA-IF-2016 - - - 750600 - - - - - UNIVERSITAETSKLINIKUM HAMBURG-EPPENDORF - UNIVERSITAETSKLINIKUM HAMBURG-EPPENDORF - - - EUR 149 825 - - - Advanced platform for profiling of therapeutic targets and functional analysis of circulating tumour cells in cancer patients - - - EUR 149 825 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - As an alternative to invasive needle biopsies, the analysis of CTCs released by metastatic lesions into the blood has been recently introduced by the PI as “liquid biopsy”. The molecular analysis of CTCs before and during - treatment could supply a real-time status of the landscape of metastatic tumor cell clones in an individual cancer patient. CTCs might reveal representative information on metastatic cells located at different sites because the blood represents a - pool of tumor cells potentially released by all lesions in the cancer patients. Moreover, blood samples can be taken sequentially during the course of the disease and therefore allow a real-time assessment of the molecular evolution of the disease - with important implications for decision making on cancer therapies. However, despite the obvious potential of CTCs as biomarker, current CTC capture assays require sophisticated, expensive and complex assay systems, which is the most important - bottleneck for a more widespread use of CTCs as liquid biopsy. The assay development in the ERC PoC Grant CAPTURE-CTC (end: 11/2016) and the successful research on improved methods for molecular characterization of CTCs in the Advanced Investigator - Grant DISSECT (end: 07/2016) of the PI has allowed to develop a novel improved platform for CTC detection. To implement our chip into future clinical decision making, we will now focus on the clinical validation of the chip platform including the - development of SOPs as basis for kits for expression of therapeutic targets and resistance mechanisms in CTCs. Moreover, the establishment of transient CTC cultures from chip-isolated tumor cells will foster drug testing in individual cancer - patients. In conclusion, the CTCapture_2.0 project will be an important prerequisite for successful future commercialization of a novel liquid biopsy assay. - - 2018-10-31, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Germany - - - CTCapture_2.0 - - - ERC-2016-PoC - - - 754453 - - - - - UNIVERSITY OF CYPRUS - UNIVERSITY OF CYPRUS - PHOEBE RESEARCH AND INNOVATION LTD - - - EUR 150 000 - - - Intelligent Building Automation Diagnostics - - - EUR 150 000 - - - Cyprus - Cyprus - Cyprus - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The emergence of networked cyber-physical systems, in which sensor/actuator networks are integrated with software algorithms, facilitates the development of advanced Building Management Systems (BMS) aimed at enhancing energy - efficiency in buildings, which accounts for 40% of the energy consumption in the EU. When a fault arises in some of the components, or an unexpected event occurs in the building, this may lead to a serious degradation in performance or, even worse, - to situations that would endanger people’s lives. Studies estimate that 20% of the energy consumed in commercial buildings for heating, ventilation, air conditioning, lighting and water heating can be attributed to various faults. Therefore, there is - a market need for an intelligent building automation diagnostic system which integrates with existing BMS to facilitate continuous and effective monitoring of the buildings. - - 2018-10-31, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Cyprus - - - Domognostics - - - ERC-2016-PoC - - - 755134 - - - - - UNIVERSITE PARIS-SUD - - - EUR 185 076 - - - Chaos-based information processing using spintronic nano-oscillators - - - EUR 185 076 - - - France - - - Higher or Secondary Education Establishments - - ChaoSpin is a frontier research project at the interface between nanomagnetism, spintronics, and nonlinear dynamics. It is motivated by the premise that the rich behaviour of nonlinear systems, in particular chaos, can be - leveraged for alternative computing paradigms. The primary objective is to establish the utility and feasibility of the nanocontact vortex oscillator, a nanoscale spintronic device, as a universal building block for chaos-based information processing - by demonstrating key technological functionalities, such as random number generation and communication using symbolic dynamics. The underlying idea is that the complexity required for computation and possible cognitive functions can be generated - within a single system, without the need of a complex array of interconnected subsystems. - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - CHAOSPIN - - - H2020-MSCA-IF-2016 - - - 751344 - - - - - POLITECNICO DI MILANO - POLITECNICO DI MILANO - CONSIGLIO NAZIONALE DELLE RICERCHE - - - EUR 150 000 - - - Nichoid: nanoengineered three-dimensional substrate for stem cell expansion - - - EUR 150 000 - - - Italy - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - "Mesenchymal stem cells (MSCs) raise a great interest for regenerative medicine for many clinical applications such as orthopaedic, plastic and reconstructive surgery, within autoimmune or degenerative disease treatment and as - immune-suppressive agents in organ transplantation. In stem cell therapy, cells are injected in the patient after an extensive in vitro manipulation aimed at obtaining a sufficient cell number able to guarantee the therapeutic effect. Currently, stem - cell "manufacturing" implies the use of “feeder” cells and additives from animal sources, hampering the clinical use mainly for safety reasons. In the context of an ERC Consolidator grant (ERC-CoG) that I currently lead, I introduced a novel - ground-breaking concept for an easy to use, repeatable, cost-effective, and safe substrate for stem cell expansion, called the “nichoid” substrate, capable of avoiding feeder cells and dangerous additives. The substrate is polymerized with a laser in - a biocompatible resin using a frontier nano-fabrication technology called “two-photon laser polymerization” (2PP). To explore the possibility of an economic exploitation of this invention covered by an Italian Patent submitted in September 2015 and - already extended as PCT, the goal of this PoC is to perform a technical and commercial feasibility to move the method developed in the PI’s laboratory during the ERC grant to the market. In particular, I plan to speed up the maturity level of the - technology further developing the production process of individual nichoids (fabrication up-scaling by at least a factor of 10, allowing to cover a culture surface of 5 squared cm in five hours), setting of an actionable IPR strategy (including a - market assessment), identification of the suitable exploitation strategy for valorising the patent/know how (licensing). The nichoid could drastically reduce down to few years the time to market of stem cell products that is currently 20 years." - - 2018-11-30, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Italy - - - NICHOIDS - - - ERC-2016-PoC - - - 754467 - - - - - UNIVERSITAT DES SAARLANDES - UNIVERSITAT DES SAARLANDES - - - EUR 150 000 - - - Mining Sandboxes for Automatic App Protection - - - EUR 150 000 - - - Germany - Germany - - - Peter Druschel - Tel.: +4968193039100 - Fax: +4968193036029 - Higher or Secondary Education Establishments - Corinna Hahn - Tel.: +49 681 95 92 3362 - Fax: +49 681 95 92 3370 - Higher or Secondary Education Establishments - Corinna Hahn - Tel.: +49 681 95 92 3362 - Fax: +49 681 95 92 3370 - - Today’s industry is more vulnerable to cyberattacks than ever. The biggest threat comes from advanced persistent threats that targets the sensitive data of a specific company. Such a threat may come along as an innocuous app - that starts its malicious behavior only when the mobile logs into the corporate network. - - 2019-02-28, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Germany - - - BOXMATE - - - ERC-2016-PoC - - - 737566 - - - - - HELSINGIN YLIOPISTO - HELSINGIN YLIOPISTO - - - EUR 1 342 132,50 - - - High-density QCD matter from first principles - - - EUR 1 342 132,50 - - - Finland - Finland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Predicting the collective properties of strongly interacting matter at the highest densities reached within the present-day Universe is one of the most prominent challenges in modern nuclear theory. It is motivated by the - desire to map out the complicated phase diagram of the theory, and perhaps even more importantly by the mystery surrounding the inner structure of neutron stars. The task is, however, severely complicated by the notorious Sign Problem of lattice QCD, - due to which no nonperturbative first principles methods are available for tackling it. - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Finland - - - DenseMatter - - - ERC-2016-COG - - - 725369 - - - - - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - - - EUR 149 648 - - - Fast Proof Reading and Correction of Complex Delineations - - - EUR 149 648 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project aims at turning the novel approach to automated delineation of complex curvilinear structures we have developed under ERC funding into industrial-grade software that can be commercialized. Our primary goal will - therefore be to transform our research software into user-friendly plugins with well-defined APIs that can be bundled with widely used commercial software platforms. - - - 2019-06-30, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Switzerland - - - FastProof - - - ERC-2016-PoC - - - 727227 - - - - - UNIVERSIDAD POMPEU FABRA - UNIVERSIDAD POMPEU FABRA - - - EUR 1 999 813 - - - Electronic AXONs: wireless microstimulators based on electronic rectification of epidermically applied currents - - - EUR 1 999 813 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - To build interfaces between the electronic domain and the human nervous system is one of the most demanding challenges of nowadays engineering. Fascinating developments have already been performed such as visual cortical - implants for the blind and cochlear implants for the deaf. Yet implantation of most electrical stimulation systems requires complex surgeries which hamper their use for the development of so-called electroceuticals. More importantly, previously - developed systems based on central stimulation units are not adequate for applications in which a large number of sites must be individually stimulated over large and mobile body parts, thus hindering neuroprosthetic solutions for patients suffering - paralysis due to spinal cord injury or other neurological disorders. A solution to these challenges could consist in developing addressable single-channel wireless microstimulators which could be implanted with simple procedures such as injection. - And, indeed, such solution was proposed and tried in the past. However, previous attempts did not achieve satisfactory success because the developed implants were stiff and too large. Further miniaturization was prevented because of the use of - inductive coupling and batteries as energy sources. Here I propose to explore an innovative method for performing electrical stimulation in which the implanted microstimulators will operate as rectifiers of bursts of innocuous high frequency current - supplied through skin electrodes shaped as garments. This approach has the potential to reduce the diameter of the implants to one-fifth the diameter of current microstimulators and, more significantly, to allow that most of the implants’ volume - consists of materials whose density and flexibility match those of neighbouring living tissues for minimizing invasiveness. In fact, implants based on the proposed method will look like short pieces of flexible thread. - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Spain - - - eAXON - - - ERC-2016-COG - - - 724244 - - - - - TECHNISCHE UNIVERSITEIT DELFT - TECHNISCHE UNIVERSITEIT DELFT - - - EUR 1 955 112,50 - - - Flows Unveiled: Multimodal Measurement in Opaque Two-Phase Flows - - - EUR 1 955 112,50 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Dispersed multiphase flows are encountered in nearly every process in nature and industry; examples include sediment in rivers, catalysts in reactors and blood flow. Despite their relevance, it is currently difficult to - accurately and efficiently model these flows. The opacity of the flows, even at moderate volume fractions, renders the common optical flow measurement tools useless. As a result, very little high-quality data is currently available to develop - (numerical) models. - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - OpaqueFlows - - - ERC-2016-COG - - - 725183 - - - - - UNIVERSITA DEGLI STUDI DI TORINO - UNIVERSITA DEGLI STUDI DI TORINO - - - EUR 1 793 421 - - - The functional interaction of EGFR and beta-catenin signalling in colorectal cancer: Genetics, mechanisms, and therapeutic potential. - - - EUR 1 793 421 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Monoclonal antibodies against the EGF receptor (EGFR) provide substantive benefit to colorectal cancer (CRC) patients. However, no genetic lesions that robustly predict ‘addiction’ to the EGFR pathway have been yet identified. - Further, even in tumours that regress after EGFR blockade, subsets of drug-tolerant cells often linger and foster ‘minimal residual disease’ (MRD), which portends tumour relapse. - - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Italy - - - BEAT - - - ERC-2016-COG - - - 724748 - - - - - NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU - NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU - - - EUR 2 000 000 - - - Cognitive Geometry: Deciphering neural concept spaces and engineering knowledge to empower smart brains in a smart society - - - EUR 2 000 000 - - - Norway - Norway - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Through smart technology, we are overwhelmed with new information. Does this unlimited access to knowledge make us smarter? One of the key challenges for modern societies is to understand how the brain assembles our rich - inventory of knowledge. Here, I will test the hypothesis that newly acquired knowledge is represented in the hippocampal formation in neural concept spaces, which are based on the coding principles and representational structures of the neural - machinery involved in spatial navigation. The key idea is that the brain’s navigation system provides the building blocks of a neural metric for knowledge. In this groundbreaking cognitive neuroscience framework, I will bridge and integrate - principles from Nobel Prize awarded neurophysiology and concepts from cognitive science and philosophy. Partly building on my ERC-StG project in which I discovered the core neural mechanisms underlying reconfiguration, integration and scaling of - memory networks, the aim of my proposal is two-fold: 1. I seek to decipher neural concept spaces and unravel the neural codes of a cognitive geometry for knowledge and its deformations. 2. I will provide a proof-of-principle framework for - next-generation neurocognitive technology and neural user models for cognitive enhancement to edit memories and engineer knowledge. Novel ‘Wikipedia’ learning tasks will be combined with state-of-the-art pattern analyses of space-resolved fMRI and - time-resolved MEG to map and quantify representational structures. I will further develop AI-inspired analyses and closed loop brain-computer interfaces to perturb and edit neural concept space. The integrative mission of my program, from cells to - systems-level involvement in cognition and to technology, opens up the exciting possibility to lay the ground for redefining cognitive neuroscience of knowledge by unravelling the fundamental neural principles of a cognitive topography and to make - critical translations to empower smart brains in a smart society. - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Norway - - - GEOCOG - - - ERC-2016-COG - - - 724836 - - - - - TECHNISCHE UNIVERSITAT DARMSTADT - TECHNISCHE UNIVERSITAT DARMSTADT - - - EUR 1 500 000 - - - Photonic Terahertz Signal Analyzers - - - EUR 1 500 000 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Spectrum analysis and vector network analysis are enabling technologies for component development throughout the microwave and millimeter wave band. Due to the lack of affordable electronics for frequencies above 100 GHz, - vector network analyzers (VNAs) have to use frequency extenders to reach into the THz frequency band (100 GHz-10 THz). The bandwidth of frequency extended electronic systems is restricted to about 50%. Several extender setups have to be used for - larger spans, requiring realignment and tedious recalibration. Further, extenders become increasingly expensive the higher the THz frequency and are, therefore, barley used. Electronic spectrum analyzers face similar problems as VNAs. Only a few - examples of highly expensive photonic, pulsed frequency comb-based systems have been demonstrated. Affordable, large bandwidth commercial THz metrology tools are missing so far. - - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - Pho-T-Lyze - - - ERC-2016-STG - - - 713780 - - - - - THE UNIVERSITY OF EDINBURGH - THE UNIVERSITY OF EDINBURGH - - - EUR 1 999 784,99 - - - Molecular control of DNA replication timing in mammalian cells - - - EUR 1 999 784,99 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - DNA replication is an essential process ensuring the transmission of genetic information and is highly regulated. Specifically, the DNA replication-timing program ensures that the sites of initiation of DNA replication, termed - origins, are not all activated simultaneously but follow a cell-type specific schedule. This pathway is conserved throughout eukaryotic evolution, however its molecular control and biological role are not fully understood. In this proposal I aim to - understand key aspects of replication-timing program by employing a combination of advanced mouse genetics, genomics, cell biology and proteomics. Currently one of the major limitations in the mammalian DNA replication field is the elusive identity - of origins. I aim to comprehensively map origins in a variety of mouse cells/tissues and relate the regulation of origin firing to the control of gene expression and three-dimensional nuclear architecture. I have discovered that Rif1 controls - replication timing and links it to nuclear three-dimensional organization. I have also revealed the existence of a novel Rif1-independent pathway that controls the timing of a significant fraction of the late-replicating genome, identified by - constitutive association with a key nuclear architecture component, Lamin B1. Here, I propose complementary approaches to understand the molecular mechanism by which Rif1 coordinates replication timing and nuclear organization as well as the - molecular underpinnings of the novel pathway instructing late-replication in Lamin B1-associated regions. Finally, my goal is to understand the in vivo biological role of the replication-timing program. Our preliminary data identify mammalian X - inactivation as a process where replication timing may play a fundamental part. My ultimate objective is to contribute to the realization of a comprehensive understanding of nuclear function, integrating the co-regulation of DNA replication with gene - expression, epigenetic inheritance and DNA repair. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - RepTime - - - ERC-2016-COG - - - 726130 - - - - - KOBENHAVNS UNIVERSITET - KOBENHAVNS UNIVERSITET - - - EUR 289 928 - - - Support to the Vice-Presidents of the ERC Scientific Council 2017 - - - EUR 289 928 - - - Denmark - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The European Research Council (ERC) provides a competitive platform for investigator-driven frontier research at the European level. It is led by a Scientific Council (ScC) consisting of 21 eminent scientists and their - President, and it is this council that independently establishes and oversees the ERC's scientific management and the implementation of its Work Programme. This project aims to support the ERC Vice-Presidents, who act on an honorary basis, in the - efficient and timely achievement of the ScC's goals in 2017. - - - 2017-12-31, closed project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - IBA-ERC-VPRES-SUP-17 - Support to the Vice-Chairs - - - CSA - Coordination and support action - - - Denmark - - - ERC VP CSA - - - H2020-IBA-ERC-VPRES-SUP-17 - - - 764466 - - - - - KOZEP-EUROPAI EGYETEM - KOZEP-EUROPAI EGYETEM - - - EUR 1 833 214 - - - Political and Business Networks - - - EUR 1 833 214 - - - Hungary - Hungary - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - I explore the role of networks involving firms---networks between firms and politicians, and networks between firms and firms--for economic outcomes. I focus on two broad questions. (1) What are the determinants and - implications of political favor networks? Although political favoritism affects allocations in many countries, its mechanisms are not well understood. I develop a new model based on the idea of trust embedded in favor networks, and test in Hungarian - data the model's implications about how political centralization shapes favoritism. I also quantify the welfare cost of misallocation created by favoritism. My results help understand how political institutions shape economic outcomes. (2) What is - the impact of supply chain networks on firm performance? Inputs from suppliers account for the majority of firm sales, yet we know little about the contribution of suppliers to firm performance. I use a field experiment in China to measure the causal - effect of suppliers and the underlying mechanisms. I then use observational data from Hungary to quantify the contribution of differences in suppliers to differences in firm performance. The results help understand how supply chains and their - misallocation shape firm and aggregate productivity. My approach to both of these questions emphasizes the role of trust embedded in firm networks and how these trust-based networks create misallocation of resources. A key component of this research - is the development of original datasets. Beyond documenting and explaining facts, I also hope to obtain policy implications on reducing favoritism and improving firm performance in developing countries. - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Hungary - - - POLBUSNETWORKS - - - ERC-2016-COG - - - 724501 - - - - - UNIVERSIDAD PABLO DE OLAVIDE - UNIVERSIDAD PABLO DE OLAVIDE - CURT-ENGELHORN ZENTRUM ARCHAOMETRIEGGMBH-CEZA - FUNDACION UNIVERSIDAD DEL NORTE - UNIVERSITA DEGLI STUDI DI PAVIA - - - EUR 1 998 875 - - - An ARTery of EMPIRE. Conquest, Commerce, Crisis, Culture and the Panamanian Junction (1513-1671) - - - EUR 1 998 875 - - - Spain - Spain - Germany - Colombia - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - European incursions onto the narrow isthmian pass that divided and connected the Atlantic and Pacific oceans made it a strategic node of the Spanish Empire and a crucial site for early modern globalization. On the front lines - of the convergence of four continents, Old Panama offers an unusual opportunity for examining the diverse, often asymmetrical impacts of cultural and commercial contacts. The role of Italian, Portuguese, British, Dutch, and French interests in the - area, as well as an influx of African slaves and Asian merchandise, have left a unique material legacy that requires an integrated, interdisciplinary approach to its varied sources. Bones, teeth and artifacts on this artery of Empire offer the - possibility of new insights into the cultural and biological impact of early globalization. They also invite an interdisciplinary approach to different groups’ tactics for survival, including possible dietary changes, and the pursuit of profit. Such - strategies may have led the diverse peoples inhabiting this junction, from indigenous allies to African and Asian bandits to European corsairs, to develop and to favor local production and Pacific trade networks at the expense of commerce with the - metropolis. - - 2020-12-31, ongoing project | - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Spain - - - ArtEmpire - - - ERC-2014-CoG - - - 648535 - - - - - CONSIGLIO NAZIONALE DELLE RICERCHE - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - UNIVERSITA DELLA CALABRIA - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSITE LIBRE DE BRUXELLES - UNIVERSITY OF STRATHCLYDE - Centre for Process Innovation Limited - GVS S.P.A. - FUJIFILM DIOSYNTH BIOTECHNOLOGIES UK LIMITED - - - EUR 3 533 813,75 - - - Revolutionising Downstream Processing of Monoclonal Antibodies by Continuous Template-Assisted Membrane Crystallization - - - EUR 3 533 813,75 - - - Italy - United Kingdom - Italy - France - Belgium - United Kingdom - United Kingdom - Italy - United Kingdom - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Separation and purification of biopharmaceuticals is today one of the most time and cost intense Downstream Processing (DSP) operations in the manufacture of commercial products. Separation and purification of proteins is - usually achieved chromatographically, with all of its disadvantages including high buffer requirements, large footprint, reuse and storage of resin studies as well as costs. Traditional DSP based on batch chromatography contribute ca. 66% of the - total production cost of anti-cancer monoclonal antibodies (mAbs). Largely contributing to this is the cost of chromatography media; for instance, the cost of 1 L of protein A resin with binding capacity of 20-70 g mAb is about 25000 Eur. By a - visionary and ambitious combination of the emerging Continuous Manufacturing Paradigm with innovative Membrane Crystallization Technology and the selective nanotemplate-recognitions directly from the fermentation broth, the AMECRYS Network aims to - develop a new Continuous Template-Assisted Membrane Crystallizer in order to revolutionize the DSP platform for mAbs production, thus achieving unprecedented purification and manufacturing efficiencies. Major research challenges will include: i) the - synthesis of 3D-nanotemplates with specific molecular recognition ability towards mAbs from complex solutions; ii) the development of tailored macroporous fluoropolymer membranes for advanced control of selective heterogeneous nucleation; iii) the - design of multilevel microfluidic devices for high-throughput mAb crystallization screening in a wide range of conditions under continuous flow (“pharma-on-a-chip” concept); iv) technology scale-up to a L-scale continuous prototype designed with - recognition of QS/GMP compliance for biopharmaceuticals. The replacement of chromatography with a single membrane-crystallization unit will lead to >60% CapEx and O&M costs decrease, 30-fold footprint reduction and high-purity solid - formulation of mAbs with preserved biological activity. - - 2020-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-1-2014 - FET-Open research projects - - - RIA - Research and Innovation action - - - Italy - - - AMECRYS - - - H2020-FETOPEN-2014-2015-RIA - - - 712965 - - - - - UNIVERSIDAD PABLO DE OLAVIDE - - - EUR 170 121,60 - - - Food in the Spanish and British Caribbean in the Nineteenth Century: Encounters, Exchanges, Identities - - - EUR 170 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - This research project aims to compare the British and Spanish empires in the nineteenth-century Caribbean. More specifically, it focuses on the discourse on food in the British and Spanish colonies. This project stems from my - doctoral research. My aim is both to find a connection between the ways in which food and diet were perceived and discussed in the British and Spanish Caribbean colonies and to evaluate the differences in the discourse on food in the two empires, - with the objective of analyzing colonial identities and imperial ideology in the Caribbean through the lens of food. My focus on food and diet sheds light on how encounters, negotiations, appropriations, rejections and interactions of culinary - practices are more than just a matter of human nutrition but rather concern fundamental issues as the construction of identities, asymmetries of power, agency of the subaltern and mutual influences. The basic assumption of this project is therefore - an analysis of the relationship between food, identity and power. - - 2017-05-31, closed project | - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - Imperial Recipes - - - H2020-MSCA-IF-2014 - - - 659541 - - - - - UNIVERSITE DE RENNES I - - - EUR 173 076 - - - Selecting non-crop flowering plants for enhancing natural enemies of crop pests in agro ecosystems under climate change perspective - - - EUR 173 076 - - - France - - - Higher or Secondary Education Establishments - - Throughout Europe, the expansion of modern, chemical-intensive agriculture is regarded as the principal cause of widespread declines in abundance and diversity beneficial arthropods. Conservation of natural enemies in - agricultural landscapes is considered the most ecologically sustainable method for biological control of agricultural pests. An ecological relevant hypothesis is that higher plant diversity, through addition of plant species able to supply accessible - food and/or shelters at different seasons of the year, can increase natural enemies' fitness. Based on existing insights in insect–plant interactions, specific floral seed mixtures (to be placed in field margins or as ground cover vegetation) can be - developed which target specific visiting biocontrol agents. However, the particular mechanisms involved and potential for practical use in farm management remain unclear. In this project I propose to consider the insect community level, including - pests and their parasitoids to evaluate the service of pest regulation provided by plant functional and evolutionary diversity at a time when climate change is expected to trigger more frequent or severe insect outbreaks. This will be done by - comparing a group of native flowering plants that are already sold by private companies for bees pollination (or other interests) in terms of their capacity to serve as source of sugar (pollen) for aphid parasitoids while resulting unattractive for - their aphid hosts. The best resulting plants will be isolately tested under greenhouse to evaluate their efficiency by measuring the resulting parasitism rate by aphid parasitoids under optimal and extremely hot conditions (summer in Valencia, Spain, - where this experiment will be performed during the secondment). Training for me will include experimental design, insect physiology, HPLC analysis, wind tunnel management, insect thermal resistance, plant flower and pollen characterization, - plant-insect interactions, statistics and others. - - 2018-01-14, closed project - - - 2016-01-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - France - - - FLORALWOOD - - - H2020-MSCA-IF-2014 - - - 660593 - - - - - CHALMERS TEKNISKA HOEGSKOLA AB - - - EUR 185 857,20 - - - Geometry and Computational Anatomy - - - EUR 185 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - The past decades have brought fascinating technological improvements of medical imaging techniques. This rapid development is accompanied by a growing need for computer based algorithms to align and extract markers from - medical images. The days of heuristically engineered computer algorithms are, however, over; competitive, state-of-the-art medical imaging software must be based on rigorous mathematics to ensure accuracy, efficiency, and stability. - - 2017-02-28, closed project | - - - 2015-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - GEOCA - - - H2020-MSCA-IF-2014 - - - 661482 - - - - - FREIE UNIVERSITAET BERLIN - - - EUR 119 595,60 - - - The Bible and the Law in Carolingian Europe: Scriptural Exegesis and Royal Legislation from Charlemagne to Charles the Bald (ca. AD 780-880) - - - EUR 119 595,60 - - - Germany - - - Higher or Secondary Education Establishments - - In what ways did the Bible shape the formation of political communities in early medieval Europe? This project studies the impact of biblical models on royal legislation in the Carolingian period (ca. AD 780-880). It proposes - a new approach to the study of the intersection between religion and politics in a formative period of European history, during which crucial institutional and conceptual resources for the development of political and religious community, statehood - and law were created. Under the Carolingian rulers from Charlemagne onwards, we can observe a steady increase of biblical quotations in legal texts issued by the ruler or by assemblies of lay and clerical advisers (so-called royal ‘capitularies’ and - conciliar decrees). Biblical prescriptions and prohibitions were either directly integrated into legal norms or used to justify the establishment or modification of norms. To understand this convergence between biblical law and royal legislation, the - rich material of Carolingian biblical exegesis is of crucial importance, since it provides access to the concepts and interpretative traditions associated with specific biblical texts in the minds of contemporaries. Authors and readers of exegetical - commentaries were often at the same time advisers to kings and important political decision makers, and also involved in the drafting of legislative texts. The project thus proposes a comparative study of legal and exegetical texts and of their - dynamic relationship. It has a twofold objective: first, to analyse the concrete impact of biblical models upon Carolingian society, and the ways in which they were used to (re)define its legal and moral framework; second, to understand the ‘social - life’ of Carolingian biblical commentaries, both as a spiritual and intellectual endeavour and as a social and political practice. - - 2017-08-31, closed project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - BIBLACE - - - H2020-MSCA-IF-2014 - - - 655748 - - - - - UNIVERSITEIT ANTWERPEN - - - EUR 172 800 - - - Physiological and environmental controls of water and ozone fluxes in a short rotation poplar plantation: from leaf to tree to ecosystem scale. - - - EUR 172 800 - - - Belgium - - - Higher or Secondary Education Establishments - - One of the consequences of global climate changes is the altered global water availability. Among the greenhouse gases (GHGs) causing global climate changes, carbon dioxide (CO2) has received most attention. Over the last - decennia the impact of rising CO2 concentrations on crops has been widely studied. The study of tropospheric ozone (O3) and its consequences on crops has not been as extensive, although O3 is a widespread and damaging air pollutant in industrialized - countries. The PHYSIO-POP project fits within the search for renewable (bio-)energies, in particular the production of woody biomass energy. The project will examine the water consumption and the sensitivity to O3 pollution of a short rotation poplar - plantation with fast-growing poplars (Populus spp.) for biomass production. - - 2017-08-31, closed project | - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Belgium - - - PHYSIO-POP - - - H2020-MSCA-IF-2014 - - - 657123 - - - - - KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN - - - EUR 159 460,80 - - - iRhom2 in neuroinflammation and pathogenesis of Alzheimer’s Disease - - - EUR 159 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - Alzheimer’s disease (AD) is the most common form of dementia in the elderly, a syndrome characterized by loss of memory and cognitive decline. AD has a dramatic socio-economical impact that is foreseen to worsen in the near - future unless a cure is found. The pathology is triggered by the accumulation of Aβ oligomers that begins a cascade culminating with the formation of neurofibrillary tangles within the neuron and cell death. Neuroinflammation is emerging to play a - key role in this process and it has been associated with the progression of the disease. - - - 2017-11-30, closed project - - - 2015-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - iRhom2 in AD - - - H2020-MSCA-IF-2014 - - - 658061 - - - - - UNIVERSITY OF LEEDS - - - EUR 183 454,80 - - - Model theory of finite and pseudofinite structures - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The project is in model theory (mathematical logic), which concerns the expressibility in logical languages of properties of mathematical structures (e.g. graphs, groups, rings). Model theory aims to identify borders between - `tame' and `wild' objects in mathematics, and to pin down abstract notions of independence and dimension and understand the geometry of `definable sets' in a structure, often with wide-ranging applications. This project focusses on classes of finite - structures (e.g. the class of all finite fields), and on the `ultraproduct' construction which converts a class of finite structures to an infinite `pseudofinite' structure' which inherits properties of the class and is amenable to model-theoretic - methods, with applications for the finite structures. Key objectives include: - - 2018-05-31, ongoing project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - MODFIN - - - H2020-MSCA-IF-2014 - - - 656422 - - - - - UNIVERSITEIT ANTWERPEN - UNIVERSITEIT ANTWERPEN - UNIVERSITAETSKLINIKUM BONN - SAN DIEGO STATE UNIVERSITY FOUNDATION - - - EUR 2 417 000 - - - Nodding Syndrome: a trans-disciplinary approach to identify the cause and decrease the incidence of river epilepsy - - - EUR 2 417 000 - - - Belgium - Belgium - Germany - United States - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - - Nodding syndrome (NS) is a neurological, incurable syndrome, currently affecting mainly children between 5 and 15 years of age in South Sudan, Uganda and Tanzania. Since 1950, when NS was first described, its cause has - remained a mystery. NS is characterized by head-nodding (an atonic form of epilepsy), often followed by clonic - tonic seizures, developmental retardation and faltering growth. In the affected regions, NS is a major public health problem associated - with severe socio-economic consequences. After exploratory missions to South Sudan, Uganda and the Democratic Republic of the Congo (DRC), we gathered epidemiological evidence that supports the hypothesis that NS is a disease caused by a pathogen - transmitted by blackflies, the vectors that transmit the parasitic worm that causes onchocerciasis. This pathogen could be an unknown neurotropic virus or another pathogen that is transmitted either independently or as a symbiont of the worm. We - postulate that this pathogen is able to cause typical NS, but also other forms of epidemic epilepsy. We hypothesise that the same disease is also endemic in other onchocerciasis hyper-endemic regions e.g. in the Mbam valley, Cameroon and the - Orientale Province, DRC (where it is referred to as “river epilepsy”). In this project we aim to investigate our hypotheses in South Sudan, Uganda, Tanzania, Cameroon and the DRC with a trans-disciplinary approach including clinical-epidemiological, - post-mortem, eco-entomological, and metagenomic studies. We will study the effect of vector control methods and ivermectin distribution on the incidence of river epilepsy. So far a multi-country study on NS was never done and nearly all previous - studies were cross-sectional, carried out during short country visits. With this long term research plan we hope to finally discover the cause of NS and detect effective control strategies to decrease the incidence of epilepsy in onchocerciasis - endemic areas. - - 2020-09-30, ongoing project | - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Belgium - - - NSETHIO - - - ERC-2014-ADG - - - 671055 - - - - - UNIVERSITEIT ANTWERPEN - - - EUR 172 800 - - - Sustainable Synthesis of Amides - - - EUR 172 800 - - - Belgium - - - Higher or Secondary Education Establishments - - Despite the ubiquity of the amide group, its synthesis is not always straightforward and the existing methods for amide formation score badly from the perspectives of economy and sustainability. This proposal aims to develop - unprecedented methodology for amide synthesis, allowing one to access “challenging” representatives. Two routes are proposed to mitigate risk and to provide complementarity. The objective of the proposal is twofold: 1) to expand the available - chemical space (allowing one to synthesize challenging amides previously considered inaccessible via library synthesis with existing methods) and 2) to substitute existing syntheses with better ones (delivering higher yields without using toxic - reagents and minimizing waste). Achieving these two objectives will have an impact on the discovery of new molecular entities and the improvement of production processes in the fine chemicals sector. The power of the new methodology will be - demonstrated on the synthesis of selected real-life examples, APIs (Active Pharmaceutical Ingredients). - - 2017-03-31, closed project | - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Belgium - - - SUSAMIDE - - - H2020-MSCA-IF-2014 - - - 657883 - - - - - FREIE UNIVERSITAET BERLIN - - - EUR 159 460,80 - - - The Rhyme: Theory and History of the rhyme in Italian and European literature - - - EUR 159 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - The objective of the present research proposal is to outline a general theory of the rhyme which might fully explain the meaning of such a device, filling a very significant gap in metrics and literary theory. The research has - already started with a forthcoming article and a 3,5 months DAAD scholarship at the Freie Univestität Berlin: the present research proposal aims at developing it into a monograph. The already written chapters concern the general theory (1-Figurative - function of the rhyme; 2-Outlines of a semiotics of the rhyme) and the intertextual implications of the rhyme. The new chapters to be written from scratch will concern: 1) the outlines of a general history of the rhyme (still lacking), from its - origins up to the 20th Century; 2) the analysis, from the outlined theoretical perspective, of the main traditional rhyming structures (terzina, ottava, sonetto, canzone etc.) and their significance to the text; 3) an account of the partial revival - of rhyme in present-day literature, in the attempt to answer the question if rhyme is still possible today and to what extent; 4) the relation of rhyme and psychoanalysis; 5) the question – hardy ever dealt with – of the relation of rhyme and rhyme - patterns to music; 6) a survey of the use of rhyme in non-literary text, such as nursery rhymes, pop music lyrics, advertisements, to check the validity and the limits of the theory beyond literature and also to address a wider audience; 7) the - outline of a “philosophy of rhyme”, examining the aesthetical conception implied by such a device; 8) an analysis of the use of the word “rhyme” when it appears in rhyme producing a metadiscourse in metrics and poetics. Besides the monograph, an - important result will be the development of a refined rhyme-search software for digitized text corpora. The research results will be disseminated also through the web (wikies, websites, high-profile literary blogs) and through participation in - workshops and international conferences. - - 2018-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - RTHRIEL - - - H2020-MSCA-IF-2015 - - - 699899 - - - - - UNIVERSITEIT ANTWERPEN - - - EUR 172 800 - - - Effects of Institutional Change on Participatory Democracy and the Involvement of Civil Society Organisations - - - EUR 172 800 - - - Belgium - - - Higher or Secondary Education Establishments - - "DemocInChange understands the current challenges to EU integration as an opportunity to rethink the interface of civil society organisations (CSOs) and EU institutions as a basis for supranational participatory democracy. It - does so by focusing on CSOs that aim to improve citizenship rights and participation for groups often marginalized in the policy-making process, more precisely by studying the effects of internal EU administrative reorganisation on the participation - of CSOs in EU decision- and policy-making. DemocInChange impacts on the future of European integration by contributing to President Juncker's political priority "A Union of Democratic Change", making European societies more innovative, inclusive and - reflective. It provides a better understanding of the linkages between equality CSOs and EU institutions, the impact of the Commission on CSOs networks and their lobbying options. - - 2018-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Belgium - - - DemocInChange - - - H2020-MSCA-IF-2015 - - - 702134 - - - - - UNIVERSITEIT ANTWERPEN - - - EUR 172 800 - - - The impact of intra household decision making on the sustainability, efficiency and equitability of household farming in sub-Saharan Africa. - - - EUR 172 800 - - - Belgium - - - Higher or Secondary Education Establishments - - This research project will assess to what extent more participatory intra household decision making about production and resource allocation contributes to more sustainable, efficient and equitable household farming systems in - sub-Saharan Africa, more specifically coffee farming systems in Uganda and Tanzania. An intervention in which household are intensely coached in participatory decision making about production, resource allocation and income expenditure will be - randomly introduced among Ugandan and Tanzanian smallholder coffee farming household. A framed economic experiment will permit to appraise if provision and appropriation behaviour by spouses in households with more participatory intra household - decision making, the treatment group, is more cooperative, than in control households. The impact of participatory intra household decision making on the sustainability, efficiency and equitability of the outcomes from provision and appropriation - behaviour in household farming systems will be studied with using individual survey data collected among spouses in treatment and control households. Inspired by the methods and findings of this project, a practical monitoring tool will be developed - to capture changes in intra household decision making about production and resource allocation and their effect on sustainable, efficient and equitable (coffee) farming in collaboration with one of the partner organisations. - - 2018-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Belgium - - - INTRACOF - - - H2020-MSCA-IF-2015 - - - 702964 - - - - - TECHNISCHE UNIVERSITEIT DELFT - - - EUR 165 598,80 - - - Flexible Li ion Batteries via Nanocrystal-Nanocarbon Scaffolded Structures - - - EUR 165 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - The aim of this proposal is to develop next generation flexible high-energy density Li ion batteries. This project seeks to advance this field by developing generalized methodologies to effectively interface flexible nano - carbon scaffolds with inorganic nanocrystals, and to obtain tailor made hierarchical assemblies as building blocks. Fabrication of these hierarchical materials whose chemical and mechanical properties can be optimized at the nano, micro and - millimeter scale are key to ensure both high energy and power density, and structurally flexible components. Our strategy will significantly increase the loading of electro-active particles (nanocrystals) and maximize their contact/exposure to - electrolytes in optimized conditions, which will improve the electrochemical properties of nanostructures. Parallel, by applying in situ electrochemical-Li-NMR-Neutron depth profile and XRD, the proposed multi-scale approach will deepen the - understanding of fundamental issues such as Li+ diffusion path ways in nanocrystal-carbon scaffolded structures (Li ion kinetics), volume expansion of nanocrystals (stress/strain issues), thermal management (heat dissipation), gas evolution (via - electrolyte decomposition) and various modes of particle degradation during battery charge/discharge cycling. - - 2018-07-31, ongoing project - - - 2016-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - FlexBatteries - - - H2020-MSCA-IF-2015 - - - 704659 - - - - - FREIE UNIVERSITAET BERLIN - - - EUR 159 460,80 - - - Higher Epsilon-Factors for Higher Local Fields - - - EUR 159 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - The goal of this project is to extend the work of Beilinson-Bloch-Esnault (BBE) on de Rahm epsilon-factors in dimension one to higher local fields. Together with my collaborators Oliver Braunling and Jesse Wolfson we have - carefully studied one of the main tools of BBE, Tate vector bundles, in an abstract context which allows to handle higher-dimensional situations. Moreover, we have successfully constructed a special case of higher epsilon-factors, called - higher-dimensional Contou-Carrère symbols, and established an array of reciprocity laws for this case. It seems very likely that similar methods, also of K-theoretic nature like in the case of symbols, can be used to shed light on higher de Rahm - epsilon-factors, and reciprocity phenomena thereof. The candidate will investigate the connection between the approach via Tate objects, and extend Patel's K-theoretic framework in a compatible way. A higher analogue of Beilinson's topological - epsilon-factors is also envisioned, and a comparison result between this theory and the de Rham version. This project offers a new viewpoint on the arithmetic and geometric behaviour of higher local fields. - - 2018-10-16, ongoing project - - - 2016-10-17 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - HEF - - - H2020-MSCA-IF-2015 - - - 701679 - - - - - FREIE UNIVERSITAET BERLIN - - - EUR 159 460,80 - - - Will this fire burn out? The topos of lovers' separation in the Italian Renaissance - - - EUR 159 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - The project aims to achieve the first in-depth study on the lyrical topos of lovers’ separation (i.e. when a lover has to go away and therefore leaves her/his beloved for some time) in the Italian Renaissance. The study is - meant to improve our knowledge about: 1) the different ways to read and re-use the tradition in the Renaissance; 2) the role of Petrarch as an authority in Renaissance love literature, also in comparison to other models; 3) the interaction between - lyrics and love treatises, as well as between literature and philosophy in the conception and representation of love in the Renaissance. For such a goal, Dr. Favaro will analyze the topos of lovers’ separation in Renaissance lyrics and love - treatises, paying attention to their mutual interaction, as well as to the relationship with the previous literary tradition and with philosophical sources (especially Neoplatonism). He will also achieve the commented editions of two little-known - Renaissance dialogues entirely devoted to the subject of lovers’ separation. - - 2017-08-31, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - FUDOGE - - - H2020-MSCA-IF-2014 - - - 653443 - - - - - FREIE UNIVERSITAET BERLIN - VIB - - - EUR 171 684 - - - Molecular mechanisms of neuronal connectivity - the synaptic code for variability and stereotypy - - - EUR 171 684 - - - Germany - Belgium - - - Higher or Secondary Education Establishments - Research Organisations - - Behaviour emerges from an interplay of various brain regions and billions of neurons forming a network. The brain acquires its organization by a series of developmental events. The correct wiring of the brain is crucially - important for all brain functions. Nevertheless, the brain is both stereotyped and variable across individuals. Currently only a subset of genes have been identified that shape specificity in connectivity and it is highly elusive what promotes - variability in synaptic connectivity and whether this is behaviourally relevant. To work on these questions I have chosen the Drosophila olfactory system, which is well-defined both on the levels of circuitry and behaviour and as such well-suited to - answer these question. Furthermore, from the perspective of circuitry, it is particularly appropriate as it is comprised of both deterministic and non-deterministic synaptic connectivity. In a first step to tackle the question, I will perform a - screen to identify genes shaping deterministic and non-deterministic neural connectivity. In parallel, I will investigate olfactory behavioural variability in the fly and correlate this to circuitry variations on the morphological, synaptic and - electrophysiological level. After identifying genes that are important for connectivity and correlating circuit to behavioural variability, I aim to modify circuit variability to alter behaviour. - - 2018-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - Molmechindividuality - - - H2020-MSCA-IF-2014 - - - 656824 - - - - - FREIE UNIVERSITAET BERLIN - FREIE UNIVERSITAET BERLIN - - - EUR 1 810 747 - - - Integration of herpesvirus into telomeres: From the mechanism of genome integration and mobilization to therapeutic intervention - - - EUR 1 810 747 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Herpesviruses cause serious diseases in humans and animals. After initial lytic infection, herpesviruses establish a quiescent (latent) infection, which allows their persistence in the host for life. We and others recently - identified a novel mechanism that allows maintenance of the genome of certain herpesviruses during latency, by integrating their complete genetic material into host telomeres. One of these viruses is human herpesvirus 6 (HHV-6) which is associated - with seizures, encephalitis, and graft rejection in transplant patients. Sporadic reactivation of the integrated virus ensures continued evolution of the virus as it spreads to a new cadre of susceptible individuals. There are critical gaps in our - knowledge regarding the fate of herpesvirus genomes during integration and reactivation as well as of viral and cellular factors involved in these processes. - - 2021-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - INTEGHER - - - ERC-2015-STG - - - 677673 - - - - - THE UNIVERSITY OF BIRMINGHAM - - - EUR 183 454,80 - - - Financing Affordable Housing Under Localism - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - This project explores the urban governance challenge of motivating institutional investment in affordable rental housing for low-middle income households. The high pressure rental markets of US and European urban financial - centres, New York, Amsterdam and London, provide sites for the study. The proposers' prior approach to studying hybrid strategies balancing social and commercial aims in housing organizations is extended to institutional investment. This takes us - beyond existing studies of financial incentive structures in institutional investment by recognizing the conflicting logics of profit and affordability, and the potential balancing role of localism. Work Package 1 reviews US experience of innovation - to attract institutional investment through tax credit incentives and community reinvestment regulation; and uses stakeholder interviews in two European urban centres to identify key local contextual factors and case study sites. Theories of - corporate social responsibility, both discretionary and negotiated, are used to develop an evaluation framework for institutionally-funded affordable housing projects. Work Package 2 explores the negotiation and terms of a sample of case study - projects using a structured evaluation methodology. Interviews with investors, policymakers and civic stakeholders reveal actor interpretations of governance arrangements that help connect these projects to finance. Investment decisions are related - back to the internal logics and structures of investors and to external incentive structures. Governance models are assessed, drawing on concepts of power and legitimacy. Work Package 3 harnesses a partnership with CECODHAS; the leading European - social housing umbrella, to convene an expert panel to apply case study findings to European contexts and to achieve impacts beyond the case study settings. This will help to uncover the potential for urban policy to empower civic actors to negotiate - finance for local affordable housing projects. - - 2017-08-31, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - REINVEST - - - H2020-MSCA-IF-2014 - - - 661659 - - - - - UNIVERSITEIT ANTWERPEN - - - EUR 93 800 - - - Imagination and Religious Credence - - - EUR 93 800 - - - Belgium - - - Higher or Secondary Education Establishments - - "Many philosophers and cognitive scientists have a habit of using the word “belief” as though it refers to a single, simple sort of cognitive attitude. But if we take empirical evidence from cognitive science of religion - seriously, we will see that this habit is a source of confusion. Just as it is a mistake in astronomy to assume that Venus and the North Star are the same kind of entity because they are both “stars,” so too it is a mistake in theorizing the nature - of belief to treat what I call religious credence and what I call factual belief as the same type of attitude. I have already argued in my paper “Religious Credence is not Factual Belief” (forthcoming, Cognition) that our best psychological theory of - cognitive attitudes, in conjunction with psychological and anthropological evidence, will treat these two attitudes differently. The research aim of the project proposed here is to elaborate on my theoretical apparatus to produce a book-length - monograph that will serve philosophers and cognitive scientists interested in religious “belief,"" and the corresponding aim for public dissemination is to make this research popularly available through essays, blogs, radio, and public debate. - - - 2016-07-31, closed project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Belgium - - - IRC - - - H2020-MSCA-IF-2014 - - - 659912 - - - - - UNIVERSITEIT ANTWERPEN - UNIVERSITEIT ANTWERPEN - - - EUR 1 499 425 - - - Order in one dimension: Functional hybrids of chirality-sorted carbon nanotubes - - - EUR 1 499 425 - - - Belgium - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The hollow structure of carbon nanotubes (CNTs) with a wide range of diameters forms an ideal one-dimensional host system to study restricted diameter-dependent molecular transport and to achieve unique polar molecular order. - For the ORDERin1D project, I will capitalize on my recent breakthroughs in the processing, filling, chiral sorting and high-resolution spectroscopic characterization of empty and filled CNTs, aiming for a diameter-dependent characterization of the - filling with various molecules, which will pave the way for the rational design of ultraselective filtermembranes, sensors, nanofluidic devices and nanohybrids with unseen control over the structural order at the molecular scale. In particular, I - recently found that dipolar molecules naturally align head-to-tail into a polar array inside the CNTs, after which their molecular directional properties such as their dipole moment and second-order nonlinear optical responses add up coherently, - groundbreaking for the development of nanophotonics applications. - - 2021-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Belgium - - - ORDERin1D - - - ERC-2015-STG - - - 679841 - - - - - UNIVERSITEIT ANTWERPEN - - - EUR 160 800 - - - Towards a fundamental understanding of a gliding arc discharge for the purpose of greenhouse gas conversion into value-added chemicals - - - EUR 160 800 - - - Belgium - - - Higher or Secondary Education Establishments - - Global climate change due to anthropogenic greenhouse gas emissions is a growing concern. The conversion of greenhouse gases (mainly CO2, CH4) to value-added chemicals or renewable fuels is an effective strategy to reduce - these emissions and an interesting process both from economic and ecological point of view. A gliding arc (GlidArc) plasma offers unique perspectives for activating inert molecules at mild conditions and allows the greenhouse gas conversion with - limited energy cost. A GlidArc is, however, very complex and poorly understood. Therefore, this project intends to obtain more fundamental insight in the plasma-mechanisms of the GlidArc for greenhouse gas conversion, by means of extensive modeling, - validated by experimental diagnostics. First, the chemical kinetics in the GlidArc for greenhouse gas conversion will be studied. Second, this plasma chemistry will be incorporated in a coupled magnetohydrodynamics (MHD) - kinetics model to study the - spatial and temporal plasma properties. The model will be validated by experiments, to be carried out during the secondment. Furthermore, the effects of various operating parameters, such as the CH4/CO2 ratio, the discharge power and the gas flow - rates, on the gas conversion, the yields of the formed products and on the energy efficiency will be analyzed, in order to predict which conditions give rise to the highest and most energy-efficient conversion. This project is very interdisciplinary, - including chemistry, physics, chemical engineering, mathematics and computer modeling, with application in environmental science and sustainable chemistry. Definitely it will extend the applicant’s skills in plasma modeling to a much broader field, - with new applications, and enhance his creative and innovative potential by advanced training in an international research environment. - - 2017-06-21, closed project - - - 2015-06-22 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Belgium - - - GlidArc - - - H2020-MSCA-IF-2014 - - - 657304 - - - - - UNIVERSITEIT ANTWERPEN - UNIVERSITEIT ANTWERPEN - - - EUR 884 725 - - - Between saints and celebrities. The devotion and promotion of stigmatics in Europe, c.1800-1950 - - - EUR 884 725 - - - Belgium - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - By far most of the historical studies on the 'golden age' of the stigmatics have focused on medical debates and religious treatises. This project wants to move beyond the traditional historiographical emphasis in at least - three ways. First of all, it will focus on the popular perception of stigmatics in the nineteenth and early twentieth century and examine how they became symbolic figures of political and religious causes. Secondly, we will study the interaction of - the 'victim souls' with their communities and examine how they were turned into 'living saints' through religious practices and discourse, and how some of them were eventually even beatified and canonized. Thirdly, we will address them as carefully - constructed religious commodities (celebrities) and rebalance the research on the selling of religion that has adopted a top-down perspective and focused primarily on the popularization of authorized cults rather than on the impact of the - commercialization from the bottom-up. Combining these three aspects in studying the stigmatics, the project will enhance our understanding of the role of (new) media and consumption practices in religious change and the construction of religious - identities. As each of these emphases calls for a study that takes into account chronological and geographical differences, we will adopt a comparative approach and examine five of the countries where most of the (hundreds of) stigmatics have been - attested (Italy, Spain, France, Germany and Belgium). This will allow us to trace larger trends as changes in the type of stigmatic (e.g. bedridden silent 'sign' or a socially engaged charismatic leader) and moments and locations of increased - attention (e.g. political crises). However, since this was the era of an internationalized Catholicism the countries will not be studied in isolation and special attention will be given to transnational attraction (e.g. pilgrims) and the related - differences in promotion and perception. - - 2019-03-31, ongoing project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Belgium - - - STIGMATICS - - - ERC-2014-STG - - - 637908 - - - - - UNIVERSITE DE RENNES I - UNIVERSITE DE RENNES I - - - EUR 2 100 230 - - - Ultrasensitive Chirped-Pulse Fourier Transform mm-Wave Detection of Transient Species in Uniform Supersonic Flows for Reaction Kinetics Studies under Extreme Conditions - - - EUR 2 100 230 - - - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This proposal aims to develop a combination of a chirped-pulse (sub)mm-wave rotational spectrometer with uniform supersonic flows generated by expansion of gases through Laval nozzles and apply it to problems at the frontiers of reaction kinetics. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - France - - - CRESUCHIRP - - - ERC-2015-AdG - - - 695724 - - - - - UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA - UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA - UNIVERSITA DEGLI STUDI DI TRIESTE - - - EUR 1 254 105 - - - The Common Core of European Administrative Law - - - EUR 1 254 105 - - - Italy - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The European dimension of administrative law is the focus of a flurry of initiatives aiming to investigate similarities and differences, and to shape common legal scenarios. A codification of the administrative procedures of - the EU has been envisaged by the European Parliament in its resolution of February 2013. A broader proposal of codification, including rule-making and contractual procedures, has been elaborated by ReNEUAL and has been discussed in a series of - workshops in 2015. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Italy - - - CoCEAL - - - ERC-2015-AdG - - - 694697 - - - - - UNIVERSITEIT HASSELT - UNIVERSITEIT HASSELT - UNIVERSITEIT ANTWERPEN - - - EUR 1 639 168 - - - Translational and Transdisciplinary research in Modeling Infectious Diseases - - - EUR 1 639 168 - - - Belgium - Belgium - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - TransMID focuses on the development of novel methods to estimate key epidemiological parameters from both serological and social contact data, with the aim to significantly expand the range of public health questions that can - be adequately addressed using such data. Using new statistical and mathematical theory and newly collected as well as readily available serological and social contact data (mainly from Europe), fundamental mathematical and epidemiological challenges - as outlined in the following work packages will be addressed: (a) frequency and density dependent mass action relating potential effective contacts to transmission dynamics in (sub)populations of different sizes with an empirical assessment using - readily available contact data, (b) behavioural and temporal variations in contact patterns and their impact on the dynamics of infectious diseases, (c) close contact household networks and the assumption of homogeneous mixing within households, (d) - estimating parameters from multivariate and serial cross-sectional serological data taking temporal effects and heterogeneity in acquisition into account in combination with the use of social contact data, and (e) finally the design of sero- and - social contact surveys with specific focus on serial cross-sectional surveys. TransMID is transdisciplinary in nature with applications on diseases of major public health interest, such as pertussis, cytomegalovirus and measles. Translational - methodology is placed at the heart of TransMID resulting in the development of a unifying methodology for other diseases and settings. The development of a toolbox and accompanying software allow easy and effective application of these fundamentally - improved techniques on many infectious diseases and in different geographic contexts, which should maximize TransMID’s impact on public health in Europe and beyond. - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Belgium - - - TransMID - - - ERC-2015-CoG - - - 682540 - - - - - FREIE UNIVERSITAET BERLIN - FREIE UNIVERSITAET BERLIN - - - EUR 1 997 452 - - - Unlocking new physics in controllably strained two-dimensional materials - - - EUR 1 997 452 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - "We will use strain engineering as an enabling tool to study previously inaccessible or hard-to-study phenomena in two-dimensional atomic crystals (2DACs: graphene, bilayer graphene, and monolayer transition metal - dichalcogenides). In our first objective, we develop unique experimental tools to control and characterize mechanical strain in 2DACs. These are the distinguishing features of our approach: (i) The use of very low disorder suspended devices; (ii) - Both uniform and controlled non-uniform strain will be induced; (iii) The level of strain will be precisely adjusted and determined in-situ during measurements. We will then use controllably-strained samples to study electrical, mechanical, thermal, - and optical properties of 2DACs: - - 2020-10-31, ongoing project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - Strained2DMaterials - - - ERC-2014-STG - - - 639739 - - - - - FREIE UNIVERSITAET BERLIN - FREIE UNIVERSITAET BERLIN - - - EUR 2 390 598 - - - Gradual and abrupt environmental change: connecting physiology, evolution and community composition - - - EUR 2 390 598 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - A major goal in ecology is to predict how environmental changes, including drivers of global change, affect communities and ecosystem functioning, with society demanding answers to these pressing questions. A key limitation of - virtually all experimental approaches addressing such questions is that treatments are delivered abruptly, while many changes occurring in nature are gradual. Here I propose to comprehensively study consequences of environmental change when delivered - abruptly vs. gradually. In order to understand and model effects of gradual vs. abrupt changes, we need to simultaneously consider physiological effects (e.g. acclimation), evolutionary changes (e.g. adaptation) and changes in community composition - and functioning. Even though changes at these levels likely interact, there is no study in which physiology, evolutionary changes and community shifts have been studied in response to a changing environmental factor. This research program thus enters - unchartered territory of empirical environmental research in proposing work at this nexus of physiology, environmental change and community composition/ function. I focus on soil fungi, key players in terrestrial ecosystems, testing a range of - gradually vs. abruptly changing environmental factors, in a range of soils, in the field and in microcosms. We connect differential responses to species traits, apply modeling and employ data syntheses across all biomes and organisms to achieve high - external validity. We carry out a set of core experiments that will afford unprecedented insight into the nature of change in a community context in response to warming, focusing on soil fungi. In these we follow evolutionary change (phenotype and - genotype), test physiological shifts by re-isolation of fungi and monitor community changes. This work will have transformative character in providing not only new mechanistic insights into effects of environmental change, but will also represent a - step change in fungal ecology. - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - Gradual_Change - - - ERC-2015-AdG - - - 694368 - - - - - UNIVERSITE DE RENNES I - UNIVERSITE DE RENNES I - - - EUR 1 998 747 - - - Mixing interfaces as reactive hotspots of porous media flows: theoretical upscaling, experimental imaging and field scale validation - - - EUR 1 998 747 - - - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In porous media, mixing interfaces such as contaminant plume fringes or boundaries between water bodies create highly reactive localized hotspots of chemical and microbiological activity, whether in engineered or natural - systems. These reactive fronts are characterized by high concentration gradients, complex flow dynamics, variable water saturation, fluctuating redox conditions and multifunctional biological communities. The spatial and temporal variability of - velocity gradients is expected to elongate mixing interfaces and steepen concentration gradients, thus strongly affecting biochemical reactivity. However, a major issue with porous media flows is that these essential micro-scale interactions are - inaccessible to direct observation. Furthermore, the lack of a validated upscaling framework from fluid- to system-scale represents a major barrier to the application of reactive transport models to natural or industrial problems. - - - 2020-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - France - - - ReactiveFronts - - - ERC-2014-CoG - - - 648377 - - - - - UNIVERSITA DEGLI STUDI DI TRIESTE - UNIVERSITA DEGLI STUDI DI TRIESTE - ELETTRA - SINCROTRONE TRIESTE SCPA - - - EUR 1 500 000 - - - INhomogenieties and fluctuations in quantum CohErent matter Phases by ultrafast optical Tomography - - - EUR 1 500 000 - - - Italy - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - Standard time domain experiments measure the time evolution of the reflected/transmitted mean number of photons in the probe pulses. The evolution of the response of a material is typically averaged over the illuminated area - as well as over many pump and probe measurements repeated stroboscopically. The aim of this project is to extend time domain optical spectroscopy beyond mean photon number measurements by performing a full Time Resolved Quantum State Reconstruction - (TRQSR) of the probe pulses as a function of the pump and probe delay. The nature of the light matter interaction and the transient light-induced states of matter will be imprinted into the probe quantum state after the interaction with the material - and can be uncovered with unprecedented detail with this new approach to time domain studies. - - 2021-05-31, ongoing project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Italy - - - INCEPT - - - ERC-2015-STG - - - 677488 - - - - - UNIVERSITE DE RENNES I - - - EUR 119 901,60 - - - Single Molecule Magnets light-switching with photochromic ligands - - - EUR 119 901,60 - - - France - - - Higher or Secondary Education Establishments - - The integration of molecular-scale components in circuits may ultimately allow the replacement of silicon-based electronics by high speed systems with low energy consumption. Because of the prominent use of magnetization-based - information storage technologies in our daily life, Single-Molecule-Magnets (SMM), which are able to interconvert between two states with opposite magnetization directions receive a great deal of attention. The potential is huge for SMM systems that - would demonstrate magnetic field- and light-driven changes in both their optical and magnetic properties because they could reproduce on a single molecule the same type of magneto-optical (MO) effects which are used for some current data storage - technologies. Photo-SMM will demonstrate that a light input can induce a modification of the magnetic and optical properties of monometallic or bimetallic SMM. This will be achieved thanks to the unprecedented association of anisotropic ions with - photochromic ligands designed to produce very different coordination environments in their two isomeric states, thus maximizing the impact of photo-isomerization on the ligand field experienced by the 4f or 3d metal ions and on the resulting magnetic - behavior. - - 2018-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - France - - - PhotoSMM - - - H2020-MSCA-IF-2015 - - - 700819 - - - - - INSTITUTO SUPERIOR DE ENGENHARIA DO PORTO - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - UNINOVA-INSTITUTO DE DESENVOLVIMENTO DE NOVAS TECNOLOGIAS-ASSOCIACAO - Teknologian tutkimuskeskus VTT Oy - AARHUS UNIVERSITET - - - EUR 3 346 660 - - - INNOVATIVE AUTONOMOUS ELECTRICAL BIOSENSOR SYNERGISTICALLY ASSEMBLED INSIDE A PASSIVE DIRECT METHANOL FUEL CELL FOR SCREENING CANCER BIOMARKERS - - - EUR 3 346 660 - - - Portugal - United Kingdom - Portugal - Finland - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - - Biosensors possess recognition elements that bind to target molecules which lead to detectable signals; they are made of two basic components: (i) a bioreceptor or biorecognition element; and (ii) a transducer element. The - bioreceptor system interacts with the target analyte and this interaction is monitored by the transducer, which converts the information into a measurable effect such as an electrical, optical or mass-sensitive signal. - - 2018-05-31, ongoing project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-1-2014 - FET-Open research projects - - - RIA - Research and Innovation action - - - Portugal - - - Symbiotic - - - H2020-FETOPEN-2014-2015-RIA - - - 665046 - - - - - UNIVERSITEIT HASSELT - - - EUR 240 530,40 - - - Spillover of Leptospira in island populations of the Channel Island fox - - - EUR 240 530,40 - - - Belgium - - - Higher or Secondary Education Establishments - - Spillover, or cross-species transmission, of pathogens from wildlife to humans is the major cause of emerging infectious diseases such as HIV, Ebola virus or SARS. Yet despite this relevance spillover as a natural process is - little known, and there is a pressing need for general theory on spillover. We propose to develop a new conceptual framework for spillover, by using an interdisciplinary approach to analyse an exceptionally complete dataset of Leptospira spillover - from California sea lions to endangered Channel Island foxes. Guided by the OneHealth vision, we will combine concepts and methods from human epidemiology, disease ecology and island biology to create a model of Leptospira spillover risk that will - provide a unique opportunity to develop and extract general concepts. Through this process, Borremans, the applying experienced researcher, will acquire a strong set of skills that will boost his expertise and significantly advance his professional - profile. He will be guided by two high-profile researchers, Lloyd-Smith (UCLA) and Hens (UHasselt) and will benefit from collaborations through their extensive international networks, ensuring Borremans’ visibility at an international level. - - 2020-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Belgium - - - SpiL - - - H2020-MSCA-IF-2015 - - - 707840 - - - - - UNIVERSITEIT ANTWERPEN - UNIVERSITEIT ANTWERPEN - - - EUR 1 208 025 - - - Mind-Bending Grammars: The dynamics of correlated multiple grammatical changes in Early Modern English writers - - - EUR 1 208 025 - - - Belgium - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Mind-Bending Grammars examines change in mental grammars of 17th century individuals across their lifespan as attested in their writings. The project treats grammar as a self-organizing network of form-meaning schemas - continuously fine-tuning itself, where activating one schema may prime formally or functionally associated ones. In analyzing multiple grammar changes in healthy adults it aspires to make a breakthrough in the cognitive modelling of grammar, and is - expected to bear on views of cognitive plasticity and self-organizing systems (e.g. ecosystems). To reach these goals it will determine (i) how change in one part of an individual’s grammar relates to change in another; (ii) to what extent grammar - change in individuals is possible and attested beyond childhood. This is still unsettled. Formal models hold that change occurs in language acquisition, social ones that it mainly results from adult interaction. The first ignore too much adult usage, - the second grammar as a system. - - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Belgium - - - MindBendingGrammars - - - ERC-2014-STG - - - 639008 - - - - - UNIVERSITEIT ANTWERPEN - KATHOLIEKE UNIVERSITEIT LEUVEN - KUNGLIGA TEKNISKA HOEGSKOLAN - STOCKHOLMS UNIVERSITET - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - BIOMERIEUX SA - BIOCARTIS NV - - - EUR 3 860 507,52 - - - New Diagnostics for Infectious Diseases: “ND4ID” - - - EUR 3 860 507,52 - - - Belgium - Belgium - Sweden - Sweden - Spain - Switzerland - France - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Infectious diseases are a major burden to public health and the global economy, not in the least due to antimicrobial resistance. Rapid point of care (POC) in vitro diagnostics (IVD) are key tools in the effective clinical - management of patients with infectious diseases. Yet there is still a large unmet clinical need for more rapid POC IVDs generating more clinically relevant, actionable information. Effectively addressing this need requires a change in the current - approach in training researchers on IVDs, generating a new ‘breed’ of IVD researchers capable of closing the gap between the clinical and technological perspective. ND4ID takes up this challenge by offering 15 ESRs a world-class first of its kind - training programme where they will be exposed to the full breadth of disciplines spanning clinical, technological and market-oriented viewpoints, from both the academic and non-academic sector. Through a set of synergistic research projects on novel - POC assays, targeting the most important and urgent clinical needs at world leading academic or private sector research groups, the ESRs are offered a holistic training program, preparing them to be lead players in the future IVD field. This training - through research is augmented by a unique comprehensive network-wide training programme covering clinical, technical and translational knowledge and skills of relevance to IVD research, development and exploitation. As such, ND4ID will deliver ESRs - that will be in high demand serving as an example for other academic and non-academic actors active in training IVD researchers and further strengthening Europe’s position in the internally competitive arena of IVD technology. - - 2020-02-29, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Belgium - - - ND4ID - - - H2020-MSCA-ITN-2015 - - - 675412 - - - - - UNIVERSIDAD PABLO DE OLAVIDE - UNIVERSIDAD PABLO DE OLAVIDE - - - EUR 1 499 625 - - - Global Encounters between China and Europe: Trade Networks, Consumption and Cultural Exchanges in Macau and Marseille (1680-1840) - - - EUR 1 499 625 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In the last decade the approaches of the global history have been emphasized in order to visualize the progress, form and method which historians have undertaken when carrying out ambitious research projects to analyse and - compare diverse geographical and cultural areas of Asia and Europe. But when dealing with comparisons and cross-cultural studies in Europe and Asia, some scholarly works have exceeded of ambiguities when defining geographical units as well as - chronology. In this project I examine perceptions and dialogues between China and Europe by analysing strategic geopolitical sites which fostered commerce, consumption and socioeconomic networks between China and Europe through a particular case - study: Macau, connecting with South China, and Marseille in Mediterranean Europe. - - - 2021-06-30, ongoing project - - - 2016-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Spain - - - GECEM - - - ERC-2015-STG - - - 679371 - - - - - UNIVERSITEIT ANTWERPEN - - - EUR 160 800 - - - Computer modelling and experimental validation of plasmas and plasma- surface interactions, for a deep insight in cryogenic etching - - - EUR 160 800 - - - Belgium - - - Higher or Secondary Education Establishments - - Microchips have caused a revolution in electronics over the last few decades. Following Moore's law, much effort has been put into continuously shrinking electronic feature dimensions. Indeed, typical feature sizes of - semi-conductor decreased from 10 µm in 1971 to 14 nm in 2014. With the shrinkage of feature sizes, plasma etching plays a more and more important role due to its anisotropy during surface processing. - - 2018-05-31, ongoing project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Belgium - - - Cryoetch - - - H2020-MSCA-IF-2015 - - - 702604 - - - - - UNIVERSITEIT ANTWERPEN - - - EUR 160 800 - - - Understanding Nitrous Oxide Production from The Mainstream Partial Nitritation and Anammox Process - - - EUR 160 800 - - - Belgium - - - Higher or Secondary Education Establishments - - Sustainable nitrogen removal from wastewater is of increasing significance in the future, aiming to achieve savings of energy consumption and operational cost as well as minimized emission of greenhouse gases. Under such a - context, the proposal of N2OPNA is developed to give first insights into nitrous oxide (N2O) production, a potent greenhouse gas, from the mainstream partial nitritation and Anammox (PNA) process. The influencing factors such as sludge particle size, - dissolved oxygen, nitrite, hydroxylamine and inorganic carbon will be investigated using enriched granular ammonia oxidizing bacteria (AOB) and Anammox bacteria. Isotopic technique will be applied to shed some light on the transformation of N2O - production pathways under varying operational conditions. Based on the process and isotopic data obtained from experiments, an integrated mathematical model for predicting N2O production in PNA system with the consideration of electron transfer, - energy balance and bacterial growth will be established. The findings in this proposal would be beneficial for the design and operation of full-scale wastewater treatment plant with the aim of N2O mitigation. - - 2018-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Belgium - - - N2OPNA - - - H2020-MSCA-IF-2015 - - - 708592 - - - - - THE UNIVERSITY OF BIRMINGHAM - - - EUR 195 454,80 - - - Aerodynamic Lift force of Trains subjected to cross winds—get it right! - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - A European-wide move to standardize the criteria for certification of railway vehicles has lead to the development of regulations for rail operators regarding velocities and pressures generated by trains and on train in cross - winds. There are two approved methodologies currently used in these regulations; physical modeling using the wind tunnel experiments and numerical modeling using computational fluid dynamics (CFD) techniques. Although there are different types of CFD - techniques, yet all of them suffer the lake of accuracy in predicting the values of the experimental lift force resulting on either overestimation or underestimation of the rolling moment coefficient. The aim of this innovative Fellowship is to - develop an accurate numerical technique based on the steady Reynolds Average Navier Stocks (RANS) capable of accurately predict the aerodynamic forces. The methodology will be based on wind tunnel experiments, moving model testing and different types - of steady and unsteady CFD techniques. In this project we will investigate for the first time the effect of surface roughness on the lift force prediction of a train subjected to cross wind. Building on the complementary skills of the Experienced - Researcher (ER) (numerical modeling) and the Beneficiary (CFD & physical modeling), we will extend significantly the existing knowledge of modeling trains on smooth surface to include a novel numerical technique to simulate the surface roughness - and hence better estimate the lift force coefficient. Our work will be validated using wind tunnel experiment at POLIMI, ITALY and underpinned with those at our industrial collaborator, Interfleet and academic partner Chalmers, Sweden. Success will - define improvements to prediction of the lift force coefficient in both physical experiments and CFD modeling, offering tangible environment and financial benefits and providing an exceptional training opportunity for the ER. - - 2018-12-07, ongoing project - - - 2016-12-08 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - LiftTrain - - - H2020-MSCA-IF-2015 - - - 701693 - - - - - UNIVERSITY OF BRISTOL - UNIVERSITY OF BRISTOL - - - EUR 2 009 429 - - - Photonic Quantum Computing - - - EUR 2 009 429 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This CoG will simultaneously address the outstanding research challenges to establishing the feasibility of large-scale photonic quantum computing by: - - 2020-05-31, ongoing project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - PQC - - - ERC-2014-CoG - - - 648667 - - - - - UNIVERSITE DE RENNES I - - - EUR 173 076 - - - Advancing Apatite Thermochronology: Novel analytical approaches for high eU apatites. - - - EUR 173 076 - - - France - - - Higher or Secondary Education Establishments - - Low temperature thermochronometry (LTT) dating is a powerful tool in geoscience, used worldwide, to provide unique information on the thermal history of rocks. Using these insights geologists can achieve a better understanding - of geological processes that have occurred over million year timescales even in settings where erosion has removed much of the geological record. Despite the success of these techniques in tackling geological problems, there still exists a major gap - in our knowledge over the fundamental principles that underlie these dating systems. Much of this uncertainty stems from an incomplete understanding of inter and intra-crystal compositional variation and the influence this has on the kinetics of the - dating system. Reaching a complete understanding of crustal thermal histories also remains a major challenge as the lowest temperature thermochronometers, apatite fission track (AFT) and apatite (U-Th)/He (AHe), are only sensitive over a temperature - range of c. 120 – 40°C. The lower temperature limit of this range is also dependant on apatites having low degrees of radiation damage that can enhance retention of He within apatite. This project will advance AFT and AHe methodology by focusing on - apatites enriched in U and Th from geological settings considered stable. The first goal is to obtain detailed REE compositional analysis using LA-ICP-MS to refine fission track annealing models and obtain high precision measurements of parent - elements to improve AFT age data. The second goal is to ensure that the maximum amount of thermal history information is extract from the 4He concentration profile in the apatite crystal. This will be achieved by a combination of 4He/3He analysis and - multi-single-grain AHe analysis of broken apatite crystals. By achieving these two goals the project will advance methodology, establish analytical capabilities at the host organisation and provide new insights into the thermal history of the crust - at stable geological settings. - - 2018-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - AAT-NAA - - - H2020-MSCA-IF-2015 - - - 706976 - - - - - SVERIGES LANTBRUKSUNIVERSITET - - - EUR 173 857,20 - - - Hot-spots of Phosphorus and Nitrogen delivery in Time and Space in agricultural catchments - - - EUR 173 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - Growing food demand exacerbates negative impacts of agriculture on the environment including diffuse nutrient losses from agricultural land to surface and groundwaters causing their eutrophication. The research will evaluate a - robust monitoring method of detecting diffuse pollution in space and time in agricultural catchments based on in situ fluorescence sensors. Tangible advantages of the fluorescence sensors: in situ deployment, low cost, real-time measurements, - mobility within the catchment, sensitivity and reliability, will be evaluated against potential limitations from quenching effects. This comprehensive evaluation is possible thanks to the host’s unique expertise and role as a coordinator of the - Swedish monitoring programme with access to the monitoring catchments, covering a range of agronomic and environmental conditions. Once tested over hot-spots and hot-moments of nutrient delivery, the method could offer an alternative and/or - complementary monitoring approach to the existing methodologies of low-frequency and fixed-location nutrient sampling. The tool will improve targeting nutrient sources and mitigation measures to the locations in which they will bring the largest - economical, societal and environmental benefits and in turn will help to achieve the aims of the EU Water Framework Directive. - - 2017-12-31, closed project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - HotPaNTS - - - H2020-MSCA-IF-2014 - - - 657192 - - - - - FREIE UNIVERSITAET BERLIN - - - EUR 159 460,80 - - - Glass, Faience and Food in Late Bronze Age Societies: An Analysis of the Socio-Economics of Urban Industries in Egyptian and Mesopotamian settlements - - - EUR 159 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - This project aims to establish an in-depth understanding of the administration and control of high-temperature industries on an urban level and the socio-economic relationship between the elite and the non-elite members of - society in Late Bronze Age (LBA) Egypt and Mesopotamia (c. 1650-1050 BC). It has been recognised in the past that within the urban settlements of Egypt and Mesopotamia the production of basic faience- and glass-objects frequently occurred in the same - urban domestic context as that of foodstuffs, using the same tools and firing structures. This analysis will particularly highlight how elite control influenced these domestic industries in an urban setting, and to what extent this influenced the - role of the members of a non-elite population and the urban infrastructure. The project will examine the following aspects: (1) The spatial analysis of the relationship between the production of glass artefacts and that of faience goods and - foodstuffs using Geographical Information Systems (GIS) technology: Concentrating on the New Kingdom Egyptian settlement of Amarna, domestic and administrative archaeological contexts containing a combination of glass-working, faience manufacture and - food production will be identified, documented and analysed in detail. (2) The organisation of workshops and areas of industrial activity throughout the urban sites and their infrastructures, within both LBA Egypt and Mesopotamia: This will also be - done using GIS, but will also include published and unpublished materials and contemporary textual sources providing knowledge about urban workshops and domestic industrial settings. (3) A comparison of industrial activities within ancient Egyptian - settlements and those taking place in contemporary ancient Mesopotamian settlement and palace sites. (4) Export and trade facilities and networks, in order to demonstrate how the produce of these industries was consumed, transported and, possibly, - traded. - - 2017-09-30, closed project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - GLASS - - - H2020-MSCA-IF-2014 - - - 653188 - - - - - FREIE UNIVERSITAET BERLIN - - - EUR 159 795,60 - - - Combining electrophysiology and cognitive computational modeling in research on meaning in language - - - EUR 159 795,60 - - - Germany - - - Higher or Secondary Education Establishments - - Language and meaning processing have been investigated with event-related brain potentials (ERPs), providing direct time-resolved measures of electrical brain activity, and with connectionist network models, providing - mechanistic implementations of the assumed processes. However, there has been very little contact between these fields, even though a combination of both methods could be highly beneficial. Based on initial evidence from the applicant, the present - project therefore aims to integrate ERPs and computational models in research on language and meaning. - - 2017-07-31, closed project - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Germany - - - Modeling ERPs - - - H2020-MSCA-IF-2014 - - - 658999 - - - - - UNIVERSITE DE RENNES I - - - EUR 246 668,40 - - - Molecular 'Click-tronics': Surface-based synthesis of single-molecule electronic components - - - EUR 246 668,40 - - - France - - - Higher or Secondary Education Establishments - - How can single-molecules be best utilized in electronics? Feature sizes of integrated circuits will reach this scale in 10-20 years (Moore’s Law). Typical molecular studies involve surface self-assembled components first - synthesised elsewhere (ex situ). Yet surface-based (in situ) preparations offer several distinct synthetic advantages – also simplifying the construction of otherwise difficult to prepare asymmetrical surface-bound motifs. - - 2018-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - France - - - MOLCLICK - - - H2020-MSCA-IF-2014 - - - 657247 - - - - - BOURNEMOUTH UNIVERSITY - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSITE D'ARTOIS - - - EUR 1 705 500 - - - High Dimensional Heterogeneous Data based Animation Techniques for Southeast Asian Intangible Cultural Heritage Digital Content - - - EUR 1 705 500 - - - United Kingdom - France - France - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - - "Although computer animation technology has been extensively used for films and games, it remains largely labour-intensive and expensive, with recent blockbuster films (e.g. Avatar, Gravity) costing around $1 million per - minute of footage. A lot of research efforts and technological breakthroughs are therefore necessary if it is to be widely applied to many low-cost applications, such as archiving and reproducing style-preserved intangible cultural heritage (ICH) - contents. The project “AniAge” is designed to answer this very challenge, using Southeast Asian ICH as the main application. Southeast Asian ICHs, e.g. local dances and puppetry, are visually and culturally rich, but are unfortunately disappearing - due to the globalized modernization. The overall aim of "AniAge" is two-fold. The first is to develop novel techniques and tools to reduce the production costs and improve the level of automation without sacrificing the control of the artists, in - order to preserve the performing art related ICHs of Southeast Asia. This involves capturing and processing versatile visual performance data, which are heterogeneous in nature and gigantic in quantity. Two areas of technological innovation are aimed - to be made, which are novel algorithms for 3D computer animation; and visual asset management with data analytics and machine learning techniques. The second is to promote knowledge exchange and dissemination between EU and Southeast Asian partners, - with a view to fostering researchers and spreading knowledge. This will be achieved by having researchers participating in the well-designed research projects, workshops, seminars and open lectures. This consortium consists of six partners, two from - the EU and four from Southeast Asia. Four work packages are designed, three for technological developments (digitalizing traditional performing arts - "DigAge", digital asset management - "ManD" and stylized animation production - "AniX") and one for - dissemination ("Dissem")." - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - United Kingdom - - - AniAge - - - H2020-MSCA-RISE-2015 - - - 691215 - - - - - UNIVERSITY OF NEWCASTLE UPON TYNE - INSTITUT POLYTECHNIQUE DE GRENOBLE - UNIVERSITAT POLITECNICA DE CATALUNYA - UNIVERSITAET FUER BODENKULTUR WIEN - ITASCA CONSULTANTS - ITASCA CONSULTING LTD - UNIVERSITE GRENOBLE ALPES - THE UNIVERSITY OF WARWICK - - - EUR 1 804 500 - - - Geohazards: Risk Assessment, Mitigation and Prevention - - - EUR 2 146 500 - - - United Kingdom - France - Spain - Austria - France - United Kingdom - France - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This proposal aims to provide a step change in terms of our capacity to assess and predict risks due to geohazards (landslides and rock slides, earthquakes, floods). This is necessary in order to make built environments and - infrastructures resilient to the increasing threat of natural hazards due to the expanding size of European cities and urban centres, increased use of infrastructure, and the effect of increased climatic variations. To achieve this we will bring - together the complementary expertise of world leading academic groups in geotechnical, geoenvironmental and seismic engineering, soil and rock mechanics, seismology, hydrology, geology together with private engineering software companies. - - - 2019-03-31, ongoing project | - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - United Kingdom - - - GEO-RAMP - - - H2020-MSCA-RISE-2014 - - - 645665 - - - - - UNIVERSITAET INNSBRUCK - ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON - UNIVERSITEIT ANTWERPEN - BIONORICA RESEARCH GMBH - GALENICA FARMAKEFTIKI VIDMICHANIA ANONYMOS ETAIRIA - VIVACELL BIOTECHNOLOGY GMBH - ROUSSELET CENTRIFUGATION SA - Eidgenössische Technische Hochschule Zürich - UNIVERSITE DE GENEVE - - - EUR 1 224 000 - - - Novel natural products for healthy ageing from Mediterranean diet and food plants of other global sources - - - EUR 1 224 000 - - - Austria - Greece - Belgium - Austria - Greece - Germany - France - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The main goal of the MediHealth project is to introduce a novel approach for the discovery of active agents of food plants from Mediterranean diet and other global sources to promote healthy ageing. This will be achieved - through an extended and well-balanced scheme of researcher’s secondments between 5 universities and 4 enterprises from EU & Associated countries as well as 4 universities from Third countries. A mutual scientific project developed on the needs - and interests of both sectors exploiting the existing complementary expertise will be the base of this proposal. Plants from the Mediterranean diet and food plants from TC will be rationally selected and will be subjected to an integrated, - interactive and comprehensive platform including in silico, in vitro (advanced cell-based assays), in vivo (flies and mice models) & metabolism assessment. Advanced analytical techniques will embrace the pharmacological evaluation process for the - efficient isolation and identification of bioactive plant constituents. Pharmacological profiling of bioactive natural products as well as identification and synthesis of their metabolites will be carried out. Finally, to carry to the stage of - development innovative products in the area of nutraceuticals/dietary supplements process-optimization studies will be performed. Within this project, core scientific multidisciplinary knowledge from different research areas will be integrated - creating valuable synergies. Expertise will be transferred by means of the seconded researchers training in environments with different research orientation where complimentary skills are required. Special attention will be given to dissemination - activities aiming to public awareness of benefits of healthy diet(s). MediHealth aspires to comprise a successful model promoting considerably researchers’ competences and long-lasting collaboration between Industry and Academia generating innovation - potential at the European and global levels. - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Austria - - - MediHealth - - - H2020-MSCA-RISE-2015 - - - 691158 - - - - - FREIE UNIVERSITAET BERLIN - - - EUR 171 460,80 - - - Neurocomputational mechanisms underlying age-related performance changes in goal-directed decisions from experience - - - EUR 171 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - The ability to make goal-directed decisions concerning one’s general well-being declines in later life. The primary—and potentially improvable—factor impacting this decline in decision-making performance is the learning - process that precedes a decision. However, little is known about age-related changes in the neurocomputational mechanisms that underlie these learning processes. The goal of the proposed project is to identify these changes. The project will first - identify age-related variability in decision-making performance across individuals and task environments, and then test what computational models from artificial intelligence best explain this variability. Because previous research has shown that - decision-making performance declines as the complexity of the choice environment increases, the focus will be on performance in cognitively demanding environments that require goal-directed decisions from experience. The project will combine data - from lab-based and home-based neurocognitive experiments, capitalizing on new developments in online experiments and webcam based eye tracking. The applicant’s unique research background brings the interdisciplinary range of skills together that is - required for the project, combining experience in computational modelling techniques from artificial intelligence, large-scale data analysis from computational linguistics, and neurocognitive experiments. The proposed project promises to further the - scientific understanding of the functional link between aging and decision-making performance. Its findings will ultimately help to empower aging decision makers to navigate cognitively demanding choice environments. - - 2018-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - AGERISK - - - H2020-MSCA-IF-2015 - - - 708507 - - - - - USTAV FYZIKALNI CHEMIE J. HEYROVSKEHO AV CR, v. v. i. - UNIVERSITEIT LEIDEN - KOBENHAVNS UNIVERSITET - AALTO-KORKEAKOULUSAATIO - AVANTIUM CHEMICALS BV - INDUSTRIE DE NORA SPA-IDN - FUNDACIO PRIVADA INSTITUT CATALA D'INVESTIGACIO QUIMICA - - - EUR 3 616 665,12 - - - Electrochemical Conversion of Renewable Electricity into Fuels and Chemicals - - - EUR 3 616 665,12 - - - Czech Republic - Netherlands - Denmark - Finland - Netherlands - Italy - Spain - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - - ELCOREL is a consortium combining 5 academic and 2 industrial beneficiaries aimed at training young researchers in the field of the conversion of water and carbon dioxide to fuels and chemicals with the aid of - electrocatalysts, of prime importance to the efficient large-scale storage of the excess renewable electricity. The consortium will (i) develop rational catalyst design principles for the electrochemical oxidation of water and the electrochemical - reduction of carbon dioxide based on the principles of quantum chemistry and large-scale quantum-chemical calculations, (ii) prepare, synthesize, characterize and test model single-crystalline and nanoparticulate catalysts, and (iii) implement high - surface area catalysts in large-scale electrolysers at industrial laboratories. The fellows to be employed in ELCOREL will be part of a unique network of academic and industrial world leaders in their respective expertises, and will receive a - dedicated multidisciplinary and intersectoral training through mandatory extensive training and research periods at the non-academic partners. Furthermore, they will go through an extensive training programme balancing scientific, personal and - entrepreneurial skills. ELCOREL will generate a new generation of electrochemical researchers ready to deal with the academic and industrial challenges of securing Europe’s future energy independence. - - 2021-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Czech Republic - - - ELCOREL - - - H2020-MSCA-ITN-2016 - - - 722614 - - - - - UNIVERSITE DE FRIBOURG - - - EUR 187 419,60 - - - Bio-inspired helicoidal multilayers for photonic innovation - - - EUR 187 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - Natural photonic structures are present in a wide variety of flora and fauna, and are useful for camouflage mechanisms, mating and pollination signalling among other biological purposes. These natural photonic architectures - constitute an invaluable source of blueprints for scientists to innovate in bio-inspired technological devices that can make a real impact in the technology based economy, for example in sensors, solar cells and lighting applications. Among the - natural structures that have an artificial counterpart with huge impact in the economy are optical thin films, where for example single layers are used for anti-reflection coatings and multilayers for high quality mirrors and filters. Interestingly, - some animals, such as the scarab beetles, exhibit unique circular polarization dependent reflection properties due to an inner helicoidal structure embedded within the multilayers of its cuticle. Fabricating such multilayers with added optical - functionalities can find applications for example in anti-counterfeiting elements or in optical applications as chirality dependent micro-mirrors. During this MSCA I aim to gain the necessary training and knowledge to become an independent researcher - in the fields of structural colour in nature and bio-inspired photonic devices. To achieve this goal, I will build up from the expertise of the host supervisor (Prof. Ullrich Steiner) and his group at the Adolphe Merkle Institute in Fribourg, - Switzerland on the field of structural colour in nature, and specifically, on their experience with the chiral structures of such beetles. I will investigate novel multilayered devices exhibiting unique optical properties by performing optical - simulations and combining state-of-the-art nano-patterning techniques together with a self-assembly method for multilayer fabrication that will yield unprecedented optical responses leading to innovative photonic devices. - - 2019-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - HELICOID - - - H2020-MSCA-IF-2016 - - - 741855 - - - - - HELSINGIN YLIOPISTO - - - EUR 191 325,60 - - - Migration, Shadow Economy and Parallel Legal Orders in Russia - - - EUR 191 325,60 - - - Finland - - - Higher or Secondary Education Establishments - - The overall aim of this fellowship is to train and develop an early career researcher through a research project that focuses on undocumented labour migrants’ legal culture and socio-legal integration in a politically hybrid - regime. The project uses the case of Russia, a hybrid political regime and the world’s second largest recipient of labour migrants, to investigate how undocumented migrants negotiate and manoeuvre around the restrictive socio-legal environment - through producing new ways of informal governance and legal order. The project aims to accomplish the following three objectives: (1) to develop a theoretically robust understanding of undocumented migrants’ socio-legal integration in politically - hybrid regimes’; (2) to produce new ethnographic material about the relationship between undocumented migrants, employers, law-enforcement structures and protection rackets (i.e. ‘parallel legal orders’) in the Russian migrant labour market and - situate these processes within a broader governance and rule of law debate; and (3) to advance the applicant’s research skills, theoretical development and professional maturity. These objectives will be accomplished through a structured and - individually tailored research and career development programme. Academically, the objectives will be achieved by exploring undocumented labour migrants’ legal culture and socio-legal integration in the context of Russia. To accomplish the career - development objectives, the applicant will obtain advanced training in qualitative and ethnographic research methods that will enable him to exploit empirical research for theoretical development and publications. The objectives pertinent to the work - programme are as follows: they provide a solid foundation for research training and data collection, which in turn is utilised for publications and a grant application (ERC Starting Grant), which play a pivotal role in the applicant’s career - advancement and consolidation of his research profile. - - 2020-02-29, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Finland - - - MIGRANT LAW RUSSIA - - - H2020-MSCA-IF-2016 - - - 751911 - - - - - UNIVERSITA DEGLI STUDI DI TORINO - - - EUR 1 412 640 - - - PhD Technology Driven Sciences: Technologies for Cultural Heritage - - - EUR 2 825 280 - - - Italy - - - Higher or Secondary Education Establishments - - T4C is a novel research and training doctoral programme in “Heritage Sciences” conceived by the University of Torino, (UNITO) with the financial support of the banking foundation Compagnia di San Paolo (CSP) and the scientific - and training involvement of a 35 local, national and international partner organisations belonging to academic and non-academic sectors. Main aim of T4C is to build up the next generation of Cultural Heritage professionals, able to develop - technological solutions and services for the restoration, the protection, the diagnostics and the valorization of cultural heritage and skilled with a complementary scientific training from socio-economic disciplines and humanities and soft skills. - Target are early stage researchers with a scientific background in chemistry, physics, biotechnology, ICT, biology and related disciplines, undergoing a genuine mobility to Italy. T4C will last 60 months and will be implemented through 2 calls for - applications, assigning a total of 18 transnational incoming fellowships. Fellows will be offered an independent and personalized scientific training choosing from two specific scientific domains: Digital Sciences and Conservation, within the - specific panels of Digital Sciences, Physical Sciences, Basic and Natural Sciences, Environmental Sciences They will be enrolled in the T4C PhD programme and will be supervised by a joint supervision of academic and non-academic supervisors. Fellows - will attend an exclusive traninig programme, encompassing basic traninig, scientific training through individual project implementation and interdisciplinary training, short term visits, secondment opportunities at non-academic premises, soft skills, - dissemination and outreach activities. T4C intends also to capitalize on the experience of the already funded Cofund project (Train2Move) in managing international mobility programmes with national and international impact and in aligning national - mechanisms to EU ones. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2016 - Co-funding of regional, national and international programmes - - - MSCA-COFUND-DP - Doctoral programmes - - - Italy - - - T4C - - - H2020-MSCA-COFUND-2016 - - - 754511 - - - - - TECHNISCHE UNIVERSITAET WIEN - - - EUR 166 156,80 - - - Infinite-dimensional symmetries, black holes, and holography - - - EUR 166 156,80 - - - Austria - - - Higher or Secondary Education Establishments - - The study of infinite-dimensional symmetries has become a very important theoretical tool in high energy physics. Playing a fundamental role within the context of AdS/CFT holographic correspondence, infinite-dimensional - symmetries and their associated mathematical structures have recently reappeared with renewed forms and in a large variety of setups, suggesting an expansion of the scope of the holographic paradigm. Carrying extremely rich information, the algebraic - architecture of field theories with infinite symmetries has led to disclose unexpected interrelations between seemingly disconnected results of theoretical physics; such as the relation between soft graviton theorems and the asymptotic symmetries of - flat spacetimes, or the conformal invariance governing the near horizon physics of highly spinning black holes. This research project is aimed at investigating different applications of infinite-dimensional symmetries and holography in theoretical - physics, with the main attention focused on black hole physics. Specific problems to be addressed include: a) the microscopic computation of non-supersymmetric black holes thermodynamics in non-AdS spaces; b) the exploration of viable extensions of - AdS/CFT correspondence to non-AdS spaces, including both warped deformations of AdS, alternative asymptotics for Kerr/CFT, and asymptotically flat spacetimes at null infinity; c) infinite-dimensional symmetries emerging at the near horizon region of - non-extremal black holes. This project includes both the transfer of knowledge and skills to the host institution and the training of the researcher in new advanced techniques in the field. As major impacts, the proposal will enhance the future - career prospects of the researcher, due to the outstanding training provided by the host, as well as foment further collaborations between the host and other European institutions in the field. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Austria - - - HoloBH - - - H2020-MSCA-IF-2016 - - - 746297 - - - - - BOURNEMOUTH UNIVERSITY - - - EUR 195 454,80 - - - Objective-based forecast evaluations for crude oil volatility. - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Oil price volatility forecasting is of major importance due to the financialisation of the oil market and the fact that the oil market participants’ decisions are based on such forecasting (e.g. oil-intensive industries, - policy makers, portfolio traders, etc). Currently, forecasters predict oil price volatility using GARCH and HAR models and evaluate the performance of these models using statistical loss-functions, such as the Mean Absolute Predictive Error. Even - more, the literature concentrates mainly its attention on two measures of volatility, namely the conditional volatility and the realized volatility. - - - 2019-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - FOROIL - - - H2020-MSCA-IF-2016 - - - 746025 - - - - - QUEEN MARY UNIVERSITY OF LONDON - - - EUR 195 454,80 - - - Investigation of the role and mechanism of action of NOD2-mediated isoform selective PI3K signalling in gut immunity and inflammation - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Inflammatory bowel disease (IBD) is a complex chronic pathology in western societies. There is an unmet need for new therapeutic strategies which can only be achieved through a better understanding of the molecular mechanisms - of host immunity. It is established that dysregulated host innate immune recognition either caused by genetic risk variants in pathogen recognition receptor (PRR) molecules or microbial factors is commonly associated with IBD. A unique PRR family - member, Nucleotide oligomerization domain (NOD)2 programs gut immunity and protection through autophagy process initiated by the recognition of microbial peptides. Deleterious mutations in NOD2 and autophagy-associated proteins are linked to IBD - susceptibility. Despite the advances made in understanding of the mechanisms underlying NOD2 biology, particularly that of autophagy, very little is known about the cell signaling components and their mechanism regulating autophagy under NOD2 - pathway. Recently, I discovered that a single Phosphoinositide 3-kinases (PI3K) isoform p110δ is integrated in NOD2 mediated autophagy process. PI3Ks are an evolutionarily conserved family of signaling molecules that integrate PRR signaling. PI3Ks - generate lipid second messengers and regulate mediated immune responses. I now propose to unravel key biological phenomenon by which p110δ PI3K convey host protective functions through NOD2-mediated autophagy, ensuring the gut immunity and tolerance. - The aims are to (1) Determine the dendritic cell-intrinsic role and mechanism(s) of action of PI3K isoforms in orchestrating anti-inflammatory processes under NOD2-mediated autophagy. (2) Discover the roles of PI3K isoforms in NLR-mediated intestinal - immunity using isoform specific PI3K gene-targeted mice alongside with pharmacological targeting strategies in vivo. My plan is integrated with animal models, immunology, cell biology, microbiology and in vivo inflammation studies to elucidate key - biological phenomena driving IBD. - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - Signalling-in-NODs - - - H2020-MSCA-IF-2016 - - - 753567 - - - - - UNIVERSITY OF WOLVERHAMPTON - - - EUR 195 454,80 - - - Governance and value-creation in SMEs in a service-dominant logic - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Small and medium-sized enterprises (SMEs) form the backbone of the European economies in terms of employment, job creation, innovation and ability to add economic value. Because of that, SMEs have received much attention from - scholars seeking to understand determinants of their competitiveness as well as from policy-makers at national and European levels aiming to provide support measures to facilitate their growth. It is well understood that SMEs command fewer resources - and are more volatile than their large counterparts, and therefore need to pursue different trajectories to compete. What is less well known is whether and how SMEs harness the potential of their boards of directors to improve value-creation thus - strengthening their competitiveness. This fellowship aims to advance knowledge by investigating how boards in SMEs contribute to value-creation within a service-dominant logic, taking into account the heterogeneity of SMEs as well as country-specific - factors. By bringing together perspectives from multiple disciplines such as strategic management, marketing, organisational behaviour and psychology, and adopting a mixed methods research design that is close to and captures the complexity of the - phenomenon, the results from the project will generate novel yet rigorous insights into the strategic dimensions of SME governance. A set of carefully designed user engagement and outreach activities will ensure that this new knowledge is transmitted - into practice and available to a wider public audience. With the help of subject-related, methodological, and professional training and secondments, this fellowship provides a unique opportunity for Dr Yar Hamidi to advance his knowledge in a subject - area he is passionate about as well as creating a sound platform from which to develop his scholarly career. - - 2019-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - GoSMEs - - - H2020-MSCA-IF-2016 - - - 748905 - - - - - UNIVERSITE DE STRASBOURG - - - EUR 173 076 - - - Vibrational Polariton Nonlinear Optics and Chemistry - - - EUR 173 076 - - - France - - - Higher or Secondary Education Establishments - - The strong coupling of a quantum state to a cavity light field has just recently revealed many fascinating effects: Chemical reactions have been dramatically slowed down and nonlinear effects have been enhanced by orders of - magnitude. These findings motivate to significantly extend the research on this novel type of light-hybridized matter. The objective of this proposal is to investigate dynamics and structural properties of molecules under vibrational strong coupling - for the first time by virtue of mid-infrared femtosecond light pulses. The proposed studies will lead to a significant advancement of the research field with respect to the fundamental understanding of strong coupling induced modifications of matter - and applications of vibrational strong coupling in photonics as well as chemistry. - - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - PlaN - - - H2020-MSCA-IF-2016 - - - 753228 - - - - - FREIE UNIVERSITAET BERLIN - - - EUR 159 460,80 - - - Between Evidence and Representation: History of Performance Art Documentation from 1970 to 1977 - - - EUR 159 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - "Between Evidence and Representation: History of Performance Art Documentation from 1970 to 1977" introduces a new historiographical approach that accounts for the dynamic development of performance art and its theories - through the history of performance documentation. Focussing on the role of performance documentation in the conservation and presentation of performance-based art from 1970 to 1977, “Between Evidence and Representation” will examine the different - strategies undertaken to provide duration and mediated access to definitionally ephemeral and immaterial events. The project’s aim is to demonstrate that, simultaneous to the formation, circulation, and acknowledgment of the category of performance - art in the early 1970s, performance documentation itself was aestheticised. The goal of the research is to show that both these changes are part of an historical process of containment of performance within the traditional framework of visual arts. - Thereby, “Between Evidence and Representation” will show how this process actively shaped the history of performance art, filling a gap in the historiography of performance art and performance documentation. The research programme, which will end in - the publication of a monograph, will be carried out in three phases. In the first phase, programmatic writings by artists and art movements will be used to map theories of performance from the 1950s to the 1970s. Referencing art journals, indexes, - and exhibitions catalogues and documents, the second phase will examine the function assigned to performance documentation from 1970 to 1977, as well as its correlation to parallel developments in the critical discourse concerning the medium of - “performance”. The last phase of the research, relying on archival sources, will provide a final corroboration to the research hypothesis through its application to four paradigmatic case studies." - - 2019-05-28, ongoing project - - - 2017-05-29 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - HiPArtDoc - - - H2020-MSCA-IF-2016 - - - 747881 - - - - - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - - - EUR 183 454,80 - - - The limits of the sciences in identifying causes and scientific laws - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Scientists rarely question the scientific methods – and their related complex theory, strong assumptions and problematic quantitative techniques – used to generate the causes and laws in their particular scientific models, - which is the guiding research question of this project. Better understanding the limits of using mathematical and statistical methods in science is important for research and policy, because these methods all lead to some degree of biased results and - scientists using them often misguidedly claim to establish strong causal relationships. This research project will investigate the underlying assumptions of quantitative methods by critically assessing the leading, most cited academic studies across - the sciences that all use some form of mathematical and statistical methods. By combining theoretical, methodological and empirical analysis, this research project will help disentangle the links between the actual methods applied by scientists and - the causal effects and scientific laws they claim to identify in their models. Identified causes and laws need to always be understood in the context of the different methods used to express them. This research project thus aims to address the gaps - in the literature on scientific methodology by providing insight and knowledge into the large set of important assumptions and limitations behind mathematical and statistical methods used to identify causes and scientific laws. By helping to increase - awareness among scientists about these biases and constraints and by outlining ways to better combine multiple methods, this project also aims to help improve scientific practice. More broadly, it hopes to help improve how we understand scientific - methodology and thus science and evidence-based policymaking. - - 2019-03-14, ongoing project - - - 2017-03-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - Alexander Krauss - - - H2020-MSCA-IF-2016 - - - 745447 - - - - - FREIE UNIVERSITAET BERLIN - - - EUR 243 352,80 - - - In Defence of Experimental Medicine: Emotional Appeals and Medical Didacticism in Germany,Britain and North America, 1870-1914 - - - EUR 243 352,80 - - - Germany - - - Higher or Secondary Education Establishments - - IDEM analyses the didactic strategies of the medical establishment in Germany, the UK and North America in educating the public about the benefits of experimental medicine. The period of focus is from 1870 to 1914: the key - expansion phase for experimental medicine in physiology, toxicology, surgery and immunology. Educational strategies were important for ensuring the on-going freedom of medical research in the face of opposition from the lay public on ethical, moral - and aesthetic grounds. Potential legal checks on medical practice motivated doctors to change anti-scientific opinion through informal educational strategies, involving the dissemination of knowledge, the disparagement of opponents of - experimentation, and influence over popular emotional reactions to medical science. IDEM probes the internal politics of the medical establishments of each area and the ways in which they learnt from each other through networks of exchange and - experience. IDEM’s objectives are: 1. To explore the pedagogical techniques and strategies of the medical establishment in their efforts to “sell” experimental medicine to the lay public, in England, Germany and North America, c. 1870-1914. 2. To - reveal the ways in which these techniques and strategies involved transnational networks and exchanges among these countries that worked to represent an orthodoxy of medical endeavour. 3. To interpret how far medical didacticism in this period - depended upon affective appeals, either instead of or embedded into the dissemination of medical knowledge, and the extent to which such appeals were gendered. 4. To analyse the extent to which the defence of medical experimentation transformed both - medical institutions and medical personalities into a) political agents and b) public bodies. 5. To assess the extent to which affective didacticism sought to change the emotional responses of both the public and of medical practitioners to the - sights, practices and results of experimental medicine. - - 2020-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Germany - - - IDEM - - - H2020-MSCA-IF-2016 - - - 742470 - - - - - UNIVERSITA DEGLI STUDI DI TRIESTE - CARDIFF UNIVERSITY - CONSIGLIO NAZIONALE DELLE RICERCHE - NOVA ID FCT - ASSOCIACAO PARA A INOVACAO E DESENVOLVIMENTO DA FCT - YD YNVISIBLE SA - MEDITEKNOLOGY SRL - A.P.E. RESEARCH SRL - UNIVERSITE DE NAMUR ASBL - - - EUR 1 237 500 - - - Engineering optoelectronic INterfaces: a global action intersecting FUndamental conceptS and technology implementatION of self-organized organic materials - - - EUR 1 237 500 - - - Italy - United Kingdom - Italy - Portugal - Portugal - Italy - Italy - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - Investing in energy efficiency and saving is crucial to support energy accessibility and environmental protection, and it is the world’s best interest to share and implement forms of energy efficiency. This implies a stronger - and effective transnational policy to promote and disseminate know-how about new technologies both at the market and R&D level. In this respect, development of projects centered on energy efficient technologies based on nanostructured organic - materials certainly is a strategic field. The progresses in mastering organic matter by self-assembly and self-organization to form ordered soft-materials revolutionized the field opening new frontiers for both fundamental and applied research. - However the route towards organic materials for application at the industrial scale is restricted by difficulties in the control and manipulation of the structural organization at the molecular level and its manifestation at higher scales. Motivated - by the potential for significant energy savings, the INFUSION project aims to create a strongly interdisciplinary and inter-sectorial environment in which the principles of self-organization are poured from the Academia into the private sector and - vice-versa to create new paradigms to engineer electrochromic devices. Through a detailed plan of 83 secondments, the project aims at cross-fertilize the electrochromic technology joining specific expertise to realize a bottom-up approach toward the - design, preparation and characterization of self-organized organic materials (chromophores, CNSs, polymers...) at different interfaces (ITO, graphene) and exhibiting superior performances (optical, durability…). For the transfer of knowledge, the - project combines the multidisciplinary expertise of 6 universities, 1 research institute, and 3 companies representing 4 EU and 2 TC countries (Pakistan and Argentina) in the field of organic chemistry, photochemistry, surface science, polymer and - materials science, and device engineering. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Italy - - - INFUSION - - - H2020-MSCA-RISE-2016 - - - 734834 - - - - - TARTU ULIKOOL - UNIVERSITE DE CERGY-PONTOISE - LINKOPINGS UNIVERSITET - TECHNISCHE UNIVERSITAT DARMSTADT - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - QUEEN MARY UNIVERSITY OF LONDON - UNIVERSIDAD POLITECNICA DE CARTAGENA - TECHNISCHE UNIVERSITEIT DELFT - UNIVERSITE PARIS DIDEROT - PARIS 7 - IVTECH SRL - ARQUIMEA INGENIERIA S.L - ESTROTECH OU - - - EUR 3 300 160,68 - - - MICroACTuators - - - EUR 3 300 160,68 - - - Estonia - France - Sweden - Germany - France - United Kingdom - Spain - Netherlands - France - Italy - Spain - Estonia - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Electroactive polymers (EAP) consist of materials capable of changing dimensions and/or shape in response to electrical stimuli. Most EAPs are also capable of generating electrical energy in response to applied mechanical - forces. These polymeric materials exhibit properties well beyond what conventional metal or plastic-based actuators can offer, including very high mechanical flexibility (can be stretched to twice their initial size), low density, a high grade of - processability, scalability, microfabrication readiness and, in most cases, low cost. Micro-EAPs enable a new broad range of applications for which large strains and forces are desirable, and for which built-in intelligence is necessary. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Estonia - - - MICACT - - - H2020-MSCA-ITN-2014 - - - 641822 - - - - - FUNDACAO CALOUSTE GULBENKIAN - - - EUR 148 635,60 - - - Role of alternative splicing in cell expansion and plant growth - - - EUR 148 635,60 - - - Portugal - - - Research Organisations - - Plant growth and morphogenic changes in response to developmental and environmental cues depend on the capacity of cells to expand correctly, which requires structural remodeling of cell walls. Importantly, abiotic stress - markedly impacts plant growth by affecting many aspects related to the cell wall, from its composition to the expression of biosynthetic and remodeling genes. The importance of transcriptional regulation of genes controlling cell wall biosynthesis - and architecture in response to environmental cues is well studied, but little is known about posttranscriptional mechanisms that affect their function. SR (serine/arginine-rich) proteins are major regulators of alternative splicing (AS), which - generates multiple transcripts from the same gene and may modulate plant stress responses. Given evidence that (i) abiotic stress affects SR protein function; (ii) mutations in SR genes cause abnormal plant growth; and (iii) SR45 directly binds mRNAs - encoding cell wall regulators, this project will investigate a role for SR-mediated regulation of AS events in cell wall regulators during plant development and abiotic stress responses. Specific objectives are to: (i) identify AS events in cell wall - regulator genes that may impact plant growth; (ii) study their regulation by SR proteins; and (iii) assess whether they determine normal plant growth under environmental stress. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Portugal - - - AS-CELLEXPAND - - - H2020-MSCA-IF-2016 - - - 750469 - - - - - INSTYTUT CHEMII FIZYCZNEJ POLSKIEJ AKADEMII NAUK - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - ECOLE NATIONALE SUPERIEURE DE CHIMIE DE PARIS - INSTITUTE FOR CONDENSED MATTER PHYSICS OF THE NATIONAL ACADEMY OF SCIENCES OF UKRAINE - UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6 - - - EUR 684 000 - - - Effects of confinement on inhomogeneous systems - - - EUR 684 000 - - - Poland - Spain - France - Ukraine - France - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - - The objective of the project is determination of universal features and specific properties of various systems spontaneously ordering into spatially inhomogeneous structures (mobile ions in solids, ionic liquid mixtures, - soft-matter and biological systems), with special focus on effects of confinement. There is striking similarity between properties of the above systems despite different interactions and length scales of inhomogeneities. The fundamental relation - between structural inhomogeneities and mechanical and thermodynamic properties is not fully understood because the exchange of knowledge between the solid-state, liquid-matter, soft-matter and biophysical communities is limited. Theoretical and - simulation approaches developed by 3 EU MS + 1 AC + 2 TC groups are closely connected or complementary. We use mean-field, liquid-matter, DFT, integral equations, field and collective-variables theories, molecular simulation approaches, and - experimental methods of electrochemistry. We will share our experience in constructing/modifying, solving and verifying experimentally models for different complex systems. The new results and theoretical approaches will help in future studies of - various inhomogeneous systems. The first work package concerns systems spontaneously forming ordered patterns, from thin films on solid surfaces through particles on interfaces to biological membranes and arid ecosystems. The pattern formation can be - exploited in innovative technology. In the second work package we will investigate ionic liquids/ionic-liquid mixtures, especially near charged surfaces and in porous media, and mobile ions in intercalation compounds. Mobile ions and ionic liquids in - porous electrodes are potentially important in innovative electrochemistry. EU/TC knowledge transfer will be by joint theoretical, simulation and experimental studies. Open workshops will be organized. Long term visits of young researchers and joint - supervision of PhD students are planned. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Poland - - - CONIN - - - H2020-MSCA-RISE-2016 - - - 734276 - - - - - UNIVERSITEIT ANTWERPEN - - - EUR 160 800 - - - CAD WALK: Enabling Computer Aided Diagnosis of Foot Pathologies through the use of Metric Learning - - - EUR 160 800 - - - Belgium - - - Higher or Secondary Education Establishments - - Dynamic plantar pressure imaging (PPI) refers to the measuring, across time, of pressure fields between the foot and the ground. PPI is used, in part, to diagnose foot problems such as metatarsalgia and plantar fasciitis. - Despite the widespread clinical use of PPI, its diagnostic potential has not been fully exploited. PPI creates large and dynamic datasets that cannot be easily analysed and interpreted by the human brain. As a result, PPI images are subsampled before - being clinically examined, which discards potentially valuable information. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Belgium - - - CAD WALK - - - H2020-MSCA-IF-2016 - - - 746614 - - - - - UNIVERSITEIT ANTWERPEN - - - EUR 160 800 - - - Novel Atg4B-inhibitors and dual [Atg4B-carbonic anhydrase]inhibitors for interfering with cytoprotective mechanisms of cancercells in the acidic tumor micro-environment. - - - EUR 160 800 - - - Belgium - - - Higher or Secondary Education Establishments - - The microenvironment of most solid tumors tends to be significantly more acidic than healthy tissue. Inadequate perfusion, oxygen limitation and cell metabolic changes, are key causative factors for this situation. The acidic - pH induces a number of specific genetic, transcriptional and metabolic effects in tumor cells. These are required for survival under increased H+-stress. Evidence is now mounting that these effects also play a major role in tumor progression, - invasiveness and the development of multi-resistance to therapy. Two pivotal adaptations related to maintaining intracellular pH homeostasis in an acidic environment, have recently received significant attention: (1) the presence of chronic autophagy - in tumors and (2) the overexpression of carbonic anhydrases (CAs), mainly CA IX and CA XII. - - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Belgium - - - ONCOPHAGY - - - H2020-MSCA-IF-2016 - - - 753221 - - - - - JYVASKYLAN YLIOPISTO - Teknologian tutkimuskeskus VTT Oy - TAMPEREEN YLIOPISTO - OULUN YLIOPISTO - LAPIN YLIOPISTO - Tiedekeskussäätiö - Federation of Finnish Learned Societies - HELSINGIN YLIOPISTO - TURUN YLIOPISTO - ITA-SUOMEN YLIOPISTO - TTY-SAATIO - - - EUR 233 584,50 - - - Researchers Changing Society - - - EUR 428 884,25 - - - Finland - Finland - Finland - Finland - Finland - Finland - Finland - Finland - Finland - Finland - Finland - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The CHANGE project aims to foster collaboration between the public and researchers in Finland in order to improve our everyday life in a rapidly changing world. This project brings together 9 universities, 1 research institute - and two expert organisations for science communication. It spans many facets of research in Finland and covers numerous individual researchers with diverse backgrounds and research topics. We will deliver a message of cutting edge research conducted - in Finland and introduce the general public with the large number of researchers and the significant work they perform. We want to break stereotypes the general public may have on researchers. The programme for activities during the night will - include content for everyone, from children to seniors. However, the specific aim is to promote research careers especially to high school and university students, and young people in general who are about to make their first real career choice. Our - message is that high education is fun and could provide them with a secured future. For the first time, so many Finnish universities and organisations will unite for a widespread European Researchers’ Night and perform simultaneously activities - targeted for the general public around the country. - - 2017-12-31, closed project | - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.5."> - - - MSCA-NIGHT-2016 - European Researchers' Night - - - CSA - Coordination and support action - - - Finland - - - CHANGE - - - H2020-MSCA-NIGHT-2016 - - - 722854 - - - - - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - - - EUR 1 999 832 - - - Pyrogenic TRansformations Affecting Climate and Health - - - EUR 1 999 832 - - - Greece - Greece - - - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - - Biomass burning (BB) is a significant contributor to global atmospheric particulate matter, with strong impacts on climate, ecosystems and public health. Yet these impacts are highly uncertain, largely owing to our inability - to track BB particulate matter and the evolution of their properties throughout most of its atmospheric lifetime. PyroTRACH will provide the necessary breakthroughs in our understanding of BB particles and their impacts by: i) deriving new markers of - biomass burning with an atmospheric lifetime that exceeds the current limitation of about a day, ii) measuring highly uncertain but critically-important climate- and health- relevant properties of aerosols both from wildfire events that occur during - summertime and from BB for heating purposes during wintertime in highly populated urban environments, iii) applying this new knowledge to quantify the contribution of biomass burning to aerosol in the Mediterranean region, and quantify its impacts on - climate and public health. Novel state-of-the-art instrumentation, portable environmental chambers and well established measurement techniques will be applied in continuous measurements as well as intensive field campaigns to study the properties and - evolution of BB particulates as they age in the atmosphere. Discovering new stable chemical markers that allow detection of BBOA many days after emission, while carefully and accurately following the climate and health-related properties of freshly - emitted and aged BBOA, allows for an unprecedented understanding of the evolution and impacts of biomass burning aerosol and its impact on the Earth System and public health. Considering the increasing occurrence of wildfires, along with decreased - emissions from fossil fuels means that accurately predicting the health and climate effects from biomass burning aerosol is one of the most important aspects of atmospheric aerosol that needs to be studied. - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Greece - - - PyroTRACH - - - ERC-2016-COG - - - 726165 - - - - - FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG - FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG - - - EUR 2 491 250 - - - Exploration of the 2D-Chemistry of Black Phosphorous - - - EUR 2 491 250 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - We propose the development of the chemistry of black phosphorus (BP). B-PhosphoChem will constitute a new text book chapter in the realm of synthetic chemistry located at the interface of inorganic-, organic-, and materials - chemistry as well as solid state physics. B-PhosphoChem will provide the basis for exciting and so far elusive applications such as ion batteries and stable high performance devices. Thin sheets of BP represent a new class of 2D materials and have - recently raised tremendous interest in the scientific community. Outstanding physical properties such as high charge carrier mobility, combined with transparency and the persistence of a band gap have been discovered. However, the chemistry of BP - remains still unexplored. B-PhosphoChem will close this gap and will a) provide the opportunity to modulate and fine tune the physical properties, b) allow for considerably improving the processability and increasing the solubility, c) establish - concepts for the desired chemical stabilization, d) give access to the combination of BP properties with those of other compound classes, e) reveal the fundamental chemical properties and reactivity principles, and f) provide methods for establishing - practical applications. Five work packages will be addressed: 1) Production of Thin Layer BP, 2) Supramolecular Chemistry of BP, 3) Intercalation Compounds of BP, 4) Covalent Chemistry of BP, and 5) BP-Based Materials and Devices. The work packages - will be supported by systematic calculations. For our group, whose core competence is synthetic organic and supramolecular chemistry, the orientation towards inorganic phosphorus chemistry constitutes a major step into a completely new direction. - However, we are convinced to be the most predestinated research group in the world successfully facing this challenge because of our leadership and well documented interdisciplinary experience in synthesizing and characterizing 0D-, 1D-, and 2D - nanostructures. - - 2022-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Germany - - - B-PhosphoChem - - - ERC-2016-ADG - - - 742145 - - - - - TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY - TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY - - - EUR 150 000 - - - Hydrogen production by membrane free chemical – electrochemical systems - - - EUR 150 000 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Until recently it was believed to be impossible to produce hydrogen through water electrolysis systems, without an electrochemical oxygen production process and without a membrane. However, in the past few years, our team was - able to develop a new technological configuration which divides the water splitting process into two phases : (1) an efficient electrochemical hydrogen production followed by a (2) spontaneous chemical oxygen production phase. By eliminating the - inefficient electrochemical water oxidation reaction (OER) we achieve a significant increase in hydrogen production efficiency. Furthermore, reducing the danger of mixing hydrogen and oxygen eliminates the need for a membrane. A membrane-free system - enables high pressure hydrogen production without the risk of gas mixture or membrane failure. Moreover, as the membrane failure is the main cause for malfunctions and offline times of alkaline and PEM electrolyzer, our technology improves system - reliability and energy efficiency. - - 2018-11-30, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Israel - - - HYMEFCECS - - - ERC-2016-PoC - - - 727606 - - - - - TECHNISCHE UNIVERSITEIT EINDHOVEN - TECHNISCHE UNIVERSITEIT EINDHOVEN - - - EUR 149 750 - - - Therapeutic antibody drug monitoring using bioluminescent sensors proteins and a smartphone - - - EUR 149 750 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Therapeutic antibodies represent an important class of newly introduced drugs and have been particularly successful in cancer therapy and the treatment of inflammatory diseases. The clearance rates of therapeutic antibodies - are known to differ per individual and correlate with survival rates. Being able to define a personalized dose per patient based on continuous monitoring of therapeutic antibody levels would therefore be beneficial both for the individual patient and - for the hospital’s budget. Our group recently developed a new platform of bioluminescent sensor proteins for antibody detection that allow antibody detection directly in blood plasma using the camera of a smart phone as the sole piece of equipment. - - - 2018-11-30, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Netherlands - - - LUMABS - - - ERC-2016-PoC - - - 755471 - - - - - KING'S COLLEGE LONDON - KING'S COLLEGE LONDON - - - EUR 2 318 719 - - - FOG-aided wireless networks for communication, cacHing and cOmputing: theoRetical and algorithmic fouNdations - - - EUR 2 318 719 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - "The FOGHORN project aims at developing the theoretical and algorithmic foundations of fog-aided wireless networks. This is an emerging class of wireless systems that leverages the synergy and complementarity of cloudification - and edge processing, two key technologies in the evolution towards 5G systems and beyond. Fog-aided wireless networks can reap the benefits of centralization via cloud processing, in terms of capital and operating cost reductions, greening, and - enhanced spectral e fficiency, while, at the same time, being able to cater to low-latency applications, such as the "tactile" internet, by means of localized intelligence at the network edge. The operation of fog-aided wireless networks poses novel - fundamental research problems pertaining to the optimal management of the communication, caching and computing resources at the cloud and at the edge, as well as to the transmission on the fronthaul network connecting cloud and edge. The solution of - these problems challenges the theoretical principles and engineering insights which have underpinned the design of existing networks. The initial research activity on the topic, of which the EU is at the forefront, focuses, by and large, on ad hoc - solutions and technologies. In contrast, the goal of this project is to develop fundamental theoretical insights and algorithmic principles with the main aim of guiding engineering choices, unlocking new academic opportunities and disclosing new - technologies. The theoretical framework is grounded in network information theory, which enables the distillation of design principles, along with signal processing, (non-convex) optimization, queuing and distributed computing to develop and analyse - algorithmic solutions." - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - FOGHORN - - - ERC-2016-COG - - - 725731 - - - - - OSPEDALE SAN RAFFAELE SRL - - - EUR 168 277,20 - - - Triggering Haematological Adoptive T-cell Immunotherapy Strategies by HUnting Novel T-cellreceptors - - - EUR 168 277,20 - - - Italy - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Recent encouraging clinical results obtained with engineered T lymphocytes and increasing advances in the genome editing field, have opened new opportunities for T-cell receptor (TCR) gene therapy as an immunotherapeutic approach for cancer. - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-SE - Society and Enterprise panel - - - Italy - - - THAT IS HUNT - - - H2020-MSCA-IF-2016 - - - 752717 - - - - - FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG - FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 996 570 - - - Microscopic Origins of Fracture Toughness - - - EUR 1 996 570 - - - Germany - Germany - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - The resistance to crack propagation is undoubtedly one of the most important properties of structural materials. However, our current mechanistic understanding of the fracture processes in typical semi-brittle materials like - steels, refractory metals or semiconductors is not sufficiently advanced to predict the fracture toughness KIc and its dependence on the microstructure, temperature and strain rate. Therefore, KIc is commonly regarded as a phenomenological material - parameter for fracture mechanics models that require experimental calibration. - - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - microKIc - - - ERC-2016-COG - - - 725483 - - - - - COPENHAGEN BUSINESS SCHOOL - COPENHAGEN BUSINESS SCHOOL - - - EUR 1 590 036 - - - Algorithmic Finance: Inquiring into the Reshaping of Financial Markets - - - EUR 1 590 036 - - - Denmark - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Present-day financial markets are turning algorithmic, as market orders are increasingly being executed by fully automated computer algorithms, without any direct human intervention. Although algorithmic finance seems to - fundamentally reshape the central dynamics in financial markets, and even though it prompts core sociological questions, it has not yet received any systematic attention. In a pioneering contribution to economic sociology and social studies of - finance, ALGOFINANCE aims to understand how and with what consequences the turn to algorithms is changing financial markets. The overall concept and central contributions of ALGOFINANCE are the following: (1) on an intra-firm level, the project - examines how the shift to algorithmic finance reshapes the ways in which trading firms operate, and does so by systematically and empirically investigating the reconfiguration of organizational structures and employee subjectivity; (2) on an - inter-algorithmic level, it offers a ground-breaking methodology (agent-based modelling informed by qualitative data) to grasp how trading algorithms interact with one another in a fully digital space; and (3) on the level of market sociality, it - proposes a novel theorization of how intra-firm and inter-algorithmic dynamics can be conceived of as introducing a particular form of sociality that is characteristic to algorithmic finance: a form of sociality-as-association heuristically analyzed - as imitation. None of these three levels have received systematic attention in the state-of-the-art literature. Addressing them will significantly advance the understanding of present-day algorithmic finance in economic sociology. By contributing - novel empirical, methodological, and theoretical understandings of the functioning and consequences of algorithms, ALGOFINANCE will pave the way for other research into digital sociology and the broader algorithmization of society. - - 2021-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Denmark - - - AlgoFinance - - - ERC-2016-COG - - - 725706 - - - - - UNIVERSIDAD PABLO DE OLAVIDE - UNIVERSIDAD PABLO DE OLAVIDE - - - EUR 150 000 - - - Targeting infertility associated to defective Insulin/IGF-1 signalling - - - EUR 150 000 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Fertility decline is the largest contributor to population ageing in the world today, and infertility negatively impacts on the mental a social wellness of the population affected. One of the causes of birth rate tumbling is - the trend of later motherhood in modern societies and the infertility associated to diabetes and polycystic ovary syndrome (PCOS). PCOS is the leading cause for ovulatory infertility, being the most common endocrine and metabolic disorder, affecting - women in reproductive age. Women suffering from diabetes frequently suffer from infertility and PCOS, while two-thirds of adult women with PCOS suffer from insulin resistance and hyperinsulinemia. The ERC-StG MitoSigAge funds research directed to - understand the process of ageing with a focus on insulin/IGF-1 signalling (IIS) and its interaction with mitochondrial metabolism. PCOS blocks oocyte maturation and ovulation, suggesting a tight link between mitochondrial energy metabolism and oocyte - development mediated by IIS. One of the applications emanating from this research lies in the identification of molecular targets to combat diabetes-associated sterility. The objective of the ERC-PoC is four-fold: First, identify evolutionarily - conserved molecular targets that, when inactivated, suppress sterility associated to defective IIS. Second, identify existing drugs for the identified targets and ascertain which compounds have the best therapeutic potential. Third, perform the - necessary patenting of the compounds for this new application and the initial steps towards the valorisation of the identified products and their commercial potential. Fourth, market studies to evaluate the commercial potential of our technology. - These steps will bridge a scientific idea from basic research to therapeutic applications. If successful, it will provide important societal and economical benefits, helping combating the downsides associated to our modern ageing society. - - 2018-10-31, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Spain - - - INFISS - - - ERC-2016-PoC - - - 737559 - - - - - UNIVERSITAET POTSDAM - UNIVERSITAET POTSDAM - LEIBNIZ - INSTITUT FUER PFLANZENGENETIK UND KULTURPFLANZENFORSCHUNG - - - EUR 1 998 525 - - - The role of chromatin in the long-term adaptation of plants to abiotic stress - - - EUR 1 998 525 - - - Germany - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - Abiotic stress is a major threat to global crop yields and this problem is likely to be exacerbated in the future. Therefore, it is very important to engineer crop plants with improved stress tolerance. A large body of - research has focussed on the immediate stress responses. However, in nature stress is frequently chronic or recurring, suggesting that temporal dynamics are an important, but under-researched, component of plant stress responses. Indeed, plants can - be primed by a stress exposure such that they respond more efficiently to the next stress incident. Such stress priming and memory may be particularly beneficial to plants due to their sessile life style. Typically, the memory of priming lasts for - several days after the end of the stress. During the past few years, my group has initiated a molecular analysis of heat stress memory in Arabidopsis thaliana. Heat stress memory is associated with sustained gene induction and transcriptional memory - and we have demonstrated that this involves lasting chromatin changes. The underlying molecular mechanisms, however, remain poorly understood. Here, I propose to combine mechanistic dissection of heat stress memory in A. thaliana with concomitant - translation of the results into the temperate cereal crop barley. In particular, we will study the following questions: What is the role of chromatin during heat stress memory? How do the transcription factors involved mediate memory-specific - outputs? How does nucleosome positioning affect heat stress memory? How do histone modifications during stress memory interact with transcription, chromatin and nuclear organization? Is heat stress memory conserved in temperate cereal species? Can we - engineer plants with improved stress memory? Using existing tools and new methodologies, the proposed analyses will yield unprecedented insight into the long-term adaptation of plants to abiotic stress and open up approaches for breeding of - stress-tolerant crops. - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - CHROMADAPT - - - ERC-2016-COG - - - 725295 - - - - - BAYERISCHE JULIUS-MAXIMILIANS UNIVERSITAT WURZBURG - BAYERISCHE JULIUS-MAXIMILIANS UNIVERSITAT WURZBURG - - - EUR 1 994 375 - - - Herpesvirus Effectors of RNA synthesis, Processing, Export and Stability - - - EUR 1 994 375 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Herpes simplex virus 1 (HSV-1) is an important human pathogen, which intensively interacts with the cellular transcriptional machinery at multiple levels during lytic infection. Employing next-generation sequencing to study - RNA synthesis, processing and translation in short intervals throughout lytic HSV-1 infection, my laboratory made the surprising observation that HSV-1 triggers widespread disruption of transcription termination of cellular but not viral genes. - Transcription commonly extends for tens-of-thousands of nucleotides beyond poly(A)-sites and into downstream genes. In contrast to textbook knowledge, HSV-1 infection does not inhibit splicing but induces a broad range of aberrant splicing events - associated with disruption of transcription termination. Exploring these fascinating phenomena will provide fundamental insights into RNA biology of human cells. - - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - HERPES - - - ERC-2016-COG - - - 721016 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 795 010 - - - Nuclear envelope attachment and dynamics of Human telomeres - unravelling nuclear organization - - - EUR 1 795 010 - - - France - France - - - Research Organisations - Research Organisations - - The spatial and temporal organization of the nucleus and its components are essential for genome regulation. During interphase of mammalian cells the nuclear envelope maintains the shape and the mechanical integrity of the - nucleus, but also provides an anchor for chromatin that is connected to its inner side. This interaction mediates the regulation of gene expression, DNA replication and the maintenance of genome stability. In human cells I found that a large subset - of telomeres, the natural ends of linear chromosomes, are transiently anchored to the nuclear envelope specifically during postmitotic nuclear assembly. Chromatin organization undergoes extensive changes during progression through the cell cycle, - particularly during mitosis with the nuclear envelope breakdown and the compaction of chromatin into metaphase chromosomes. The interaction between chromosome ends and the nuclear envelope at the stage where the nucleus is reforming post-mitosis - suggests a new role for telomeres in nuclear organization. My aims are 1) to screen for interacting partners that mediate the cell-cycle dependent telomere tethering to the nuclear membrane; 2) to unravel the molecular mechanism of telomere-nuclear - envelope association over the cell cycle by combining biochemistry and state-of-the-art microscopy; 3) to map the subset of chromosomes which ends are tethered using subtelomere specific FISH probes and determine whether they are conserved throughout - cell divisions and if it plays a role in organizing chromosome territories; 4) to examine telomere dynamics in cells from premature aging syndromes affecting the nuclear envelope integrity using live imaging confocal microscopy, and understand the - connection between telomeres, nuclear envelope, and aging. The originality of my scientific approach is to combine state-of-the-art cell biology, biochemistry, and molecular biology for an integrated view of human telomere function in nuclear - organization. - - 2022-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - TeloHOOK - - - ERC-2016-STG - - - 714653 - - - - - PARIS-LODRON-UNIVERSITAT SALZBURG - PARIS-LODRON-UNIVERSITAT SALZBURG - - - EUR 1 705 833 - - - Power in international trade negotiations - - - EUR 1 705 833 - - - Austria - Austria - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - For the last twenty years, countries across the globe have negotiated a large number of preferential trade agreements. In parallel, trade negotiations have taken place in the framework of the World Trade Organization. These - negotiations not only deal with tariffs, but also cover investments, competition policy, labour standards and much more. With much at stake, the extent to which different countries are able to achieve their preferred outcomes in these negotiations is - of broad interest. In this project, I address this topic by asking: what makes some countries have more bargaining power than others in these negotiations? In other words, what explains variation in bargaining power in trade negotiations? - - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Austria - - - TRADEPOWER - - - ERC-2016-COG - - - 724107 - - - - - TECHNISCHE UNIVERSITEIT DELFT - TECHNISCHE UNIVERSITEIT DELFT - - - EUR 1 998 750 - - - New discrete choice theory for understanding moral decision making behaviour - - - EUR 1 998 750 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Discrete choice theory provides a mathematically rigorous framework to analyse and predict choice behaviour. While many of the theory’s key developments originate from the domain of transportation (mobility, travel behaviour), - it is now widely used throughout the social sciences. - - - 2022-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - BEHAVE - - - ERC-2016-COG - - - 724431 - - - - - FUNDACION CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III - FUNDACION CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III - - - EUR 1 995 000 - - - Functional characterisation of mitochondrial metabolic adaptations to innate sensing in dendritic cell subsets - - - EUR 1 995 000 - - - Spain - Spain - - - Research Organisations - Research Organisations - - Immunometabolism is an emerging research field that promises to generate novel targets for manipulation of functional responses in immune cells. Pioneering studies are beginning to unveil how innate sensing leads to metabolic - reprogramming of immune cells. We became interested in the possible metabolic consequences of innate sensing by myeloid cells because of our previous work showing how mouse and human dendritic cell (DC) subsets detect danger signals from microbes and - damaged tissues. Our current data show that sensing of live bacteria triggers a profound reorganisation of the mitochondrial electron transport chain (ETC) in macrophages, with a switch in the relative contribution of ETC complexes I and II to - mitochondrial respiration that impacts immune response. As we pursue novel strategies to manipulate DC function, and supported by our preliminary data in DCs, we hypothesise that innate sensing induces mitochondrial adaptations in DCs and that - targeting mitochondrial metabolism will affect DC function. Our goals are: 1) to characterise how innate sensing of danger signals from microbes or from tissue damage modulate mitochondrial adaptations and metabolic reprogramming in mouse and human - DC subsets; 2) to dissect the molecular mechanisms that connect innate sensing and mitochondrial adaptations in DCs, using biased and unbiased cutting-edge proteomics approaches; 3) to address the impact of manipulating mitochondrial biology on mouse - and human DC metabolism and function; and 4) to assess the functional in vivo effects of targeting mitochondrial biology in DCs in homeostasis and disease. The characterisation of the molecular mechanisms that link innate sensing and mitochondrial - metabolism with DC function will open new avenues for basic research in mitochondrial biology and for the emerging field of immunometabolism. Functional targeting of DC mitochondrial metabolism has great potential for the discovery of new strategies - to modulate immunity and tolerance. - - 2022-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Spain - - - MITOMAD - - - ERC-2016-COG - - - 725091 - - - - - UNIVERSIDAD POMPEU FABRA - UNIVERSIDAD POMPEU FABRA - - - EUR 1 381 250 - - - Global Production Networks and Macroeconomic Interdependence - - - EUR 1 381 250 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Researchers and policymakers alike have highlighted the potential efficiency gains of a global production structure. However, such linkages also raise the possibility of risks. This proposal tackles both empirical and - theoretical challenges in incorporating the microeconomic structure of trade and international production networks in the study of the propagation of shocks internationally, and their impact on macroeconomic interdependence. Using newly constructed - micro-level datasets, I provide quantitative analysis of the importance of the linkages in multicountry general equilibrium models of trade. First, using firm export and imported-input linkages, I provide a novel model-based estimation strategy to - identify the role of country and firm-level shocks, and the implications of these estimates for the transmission of shocks across borders. By using structural trade models to estimate shocks at the firm level and studying the implications for the - transmission of shocks across borders, I help bridge the micro-macro nexus in international economics. Second, I take an even more granular focus by studying the role of firm-to-firm production linkages in transmitting shocks across countries. To do - so, I exploit a novel matching procedure between a country’s administrative dataset and cross-country firm-level data. I further build on these data by adding in domestic bank-firm relationships. This strategy allows for the study of how financial - shocks are exported abroad via firms’ trade and multinational linkages. Third, I incorporate the insights from the empirical work into a full-scale multicountry general equilibrium model of trade, which allows for firm-level heterogeneity and - microeconomic and macroeconomics shocks. I use the model for a quantitative study of the cross-country transmission of the different shocks via trade. This allows me to perform counterfactuals and examine the impact of policies, such as how opening - to trade impacts macroeconomic interdependence. - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Spain - - - GLOBALMACRO - - - ERC-2016-COG - - - 726168 - - - - - MEDIZINISCHE HOCHSCHULE HANNOVER - MEDIZINISCHE HOCHSCHULE HANNOVER - - - EUR 1 499 750 - - - Targeting the transcriptional landscape in infant AML - - - EUR 1 499 750 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Infant acute myeloid leukemia (AML) has a dismal prognosis, with a high prevalence of unfavorable features and increased susceptibility to therapy-related toxicities, highlighting the need for innovative treatment approaches. - Despite the discovery of an enormous number and diversity of transcriptional products arising from the previously presumed wastelands of the non-protein-coding genome, our knowledge of non-coding RNAs is far from being incorporated into standards of - AML diagnosis and treatment. I hypothesize that the highly developmental stage- and cell-specific expression of long non-coding RNAs shapes a chromatin and transcriptional landscape in fetal hematopoietic stem cells that renders them permissive - towards transformation. I predict this landscape to synergize with particular oncogenes that are otherwise not oncogenic in adult cells, by providing a fertile transcriptional background for establishing and maintaining oncogenic programs. Therefore, - the non-coding transcriptome, inherited from the fetal cell of origin, may reflect a previously unrecognized Achilles heel of infant AML, which I will identify with my expertise to understand and edit the AML genome and transcriptome. - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - iAML-lncTARGET - - - ERC-2016-STG - - - 714226 - - - - - INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM - INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM - - - EUR 1 986 125 - - - Applying silicon solar cell technology to revolutionize the design of thin-film solar cells and enhance their efficiency, cost and stability - - - EUR 1 986 125 - - - Belgium - Belgium - - - Research Organisations - Research Organisations - - Thin film (TF) photovoltaics (PV) hold high potential for Building Integrated PV, an important market as European buildings require to be nearly zero-energy by 2020. Currently, Cu(In,Ga)(S,Se)2 (= CIGS(e)) TF solar cells have - high efficiency, but also a simple one-dimensional cell design with stability and reliability concerns. Furthermore, its present research has been mainly focused on improving the absorber and buffer layers. - - - 2022-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Belgium - - - Uniting PV - - - ERC-2016-STG - - - 715027 - - - - - WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER - WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER - - - EUR 1 989 812,50 - - - Photonic integrated quantum transceivers - - - EUR 1 989 812,50 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Quantum processors are envisioned to conquer ultimate challenges in information processing and to enable simulations of complex physical processes that are intractable with classical computers. Among the various experimental - approaches to implement such devices, scalable technologies are particularly promising because they allow for the realization of large numbers of quantum components in circuit form. For upscaling towards functional applications distributed systems - will be needed to overcome stringent limitations in quantum control, provided that high-bandwidth quantum links can be established between the individual nodes. For this purpose the use of single photons is especially attractive due to compatibility - with existing fibre-optical infrastructure. However, their use in replicable, integrated optical circuits remains largely unexplored for non-classical applications. - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - PINQS - - - ERC-2016-COG - - - 724707 - - - - - UNIVERSITY OF YORK - - - EUR 183 454,80 - - - Semi-Parametric Econometric Models: Health, Obesity and Patient Expenditures - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Econometric modelling of healthcare costs serves many purposes: to obtain key parameters in cost-effectiveness analyses; to implement risk adjustment in insurance systems; and to examine the impact of risk factors such as - smoking and obesity. Modelling healthcare costs is challenging because the cost data are typically non-negative, heavy tailed and highly skewed. - - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SPEM - - - H2020-MSCA-IF-2016 - - - 740654 - - - - - FREIE UNIVERSITAET BERLIN - FREIE UNIVERSITAET BERLIN - - - EUR 1 489 919 - - - Emotional Machines:The Technological Transformation of Intimacy in Japan - - - EUR 1 489 919 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - EMTECH analyzes the relationship between aesthetic works on human-robot interaction in Japan and cutting-edge advances in robotics and artificial intelligence. Its central hypothesis argues that a tradition of literary, - artistic, and other media forms of cultural production on human-robot relationships particular to Japan is currently being built into emotionally-intelligent companion robots with the ability to understand, record, and elicit emotions in its users, - consequently expanding the capacities for humans to create affective bonds with machines and transforming structures of intimacy that sustain traditional social institutions. In its most ambitious claim, EMTECH argues that this cultural tradition has - played a primary role in inspiring the recently-emerging mass production of domestic robots with technology that can register and record facial expressions, heart rate, skin conductance, and other signs of affect not consciously recognized by humans, - thus generating new kinds of scientific data on human affect that fundamentally challenges previous understandings of emotion. Through the textual analysis of literary work on robot imaginaries and ethnographic fieldwork on human-robot interaction in - homes, palliative care centers, and engineering laboratories, EMTECH’s purpose is to collect qualitative data on new technologies of emotion management in order to advance literary and cultural theory’s contributions to the affective sciences, as - well as to inform public discussions on issues of data collection, privacy, and other ethical concerns raised by the adoption of emotionally-intelligent robots in the home. Leveraging research in the humanities to critique emotional models employed - by robotics engineers and designers, and implementing novel research methods such as the use of robots in both literary critique and ethnographic fieldwork, EMTECH promises to yield groundbreaking data of both theoretical and methodological - application across the human sciences. - - 2022-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - EMTECH - - - ERC-2016-STG - - - 714666 - - - - - KOBENHAVNS UNIVERSITET - KOBENHAVNS UNIVERSITET - - - EUR 1 987 811 - - - Reprogramming of small RNA function in plant-pathogen interactions - - - EUR 1 987 811 - - - Denmark - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - RNA silencing relies on small RNAs that act in RNA induced silencing complexes (RISCs). RISCs use base pairing to select mRNAs or invading nucleic acids such as viruses for repression. RNA silencing may facilitate gene - expression changes, for example in host-pathogen interactions. Such changes require reprogramming of RISC, since a different set of RNAs must be rapidly repressed upon pathogen perception. RISC reprogramming is non-trivial: new small RNAs must be - produced and be rapidly incorporated into RISC, while unwanted repression by pre-existing RISCs must be eliminated. This project focuses on understanding three central aspects of RISC reprogramming in plant-pathogen interactions. First, we will - define mechanisms that allow invading RNA, but not self-RNA, to engage in positive feedback loops for small RNA synthesis, and we will investigate the specific importance of these positive feedback loops in antiviral defense. Second, we will explore - how rapid proteolysis of the central RISC component ARGONAUTE1 (AGO1) governs rapid incorporation of newly synthesized small RNA. We will also explore the hypothesis that non-RNA bound AGO1 is degraded to minimize vulnerability to pathogens that use - small RNAs as virulence factors to repress host immune signaling. The relevance of these mechanisms of AGO1 proteolysis in plant immunity will be investigated. These studies take advantage of our recent discovery of proteins required specifically for - turnover of AGO1. Finally, we explore the hypothesis that rapid chemical modification of mRNA by N6-adenosine methylation (m6A) may bring mRNAs with poor small RNA binding sites under RISC repression. This scenario is supported by interactions - between m6A reader proteins and AGO1 discovered in current work in the group. This mechanism may enable reprogramming of RISC specificity rather than composition upon pathogen perception. Our project will fill gaps in knowledge on RNA silencing and - elucidate their importance in plant immunity. - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Denmark - - - PATHORISC - - - ERC-2016-COG - - - 726417 - - - - - TECHNISCHE UNIVERSITEIT EINDHOVEN - CHALMERS TEKNISKA HOEGSKOLA AB - KATHOLIEKE UNIVERSITEIT LEUVEN - NXP SEMICONDUCTORS NETHERLANDS BV - ERICSSON AB - ORBAN MICROWAVE PRODUCTS NV - - - EUR 3 078 374,40 - - - Silicon-based Ka-band massive MIMO antenna systems for new telecommunication services - - - EUR 3 078 374,40 - - - Netherlands - Sweden - Belgium - Netherlands - Sweden - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The continuously growing need for higher data-rates and, therefore, more signal bandwidth in wireless communications, requires the use of multi-antenna base stations employing the recently introduced massive - Multiple-Input-Multiple-Output (MIMO) concept and operating at millimeter-wave frequencies, e.g. 30 GHz. However, the implementation of such complex antenna systems into highly-integrated, energy- and cost-effective solutions is very challenging. - Therefore, we propose an innovative antenna system concept utilizing silicon semiconductor electronics that can generate or receive at millimeter-wave frequencies in order to truly expand wireless communications into the outer limits of radio - technology. SILIKA establishes a training network with leading R&D labs from European industries, universities and technology institutes in the domain of wireless infrastructure. This will be achieved by a multi-disciplinary approach combining - expertise in all required areas to create a breakthrough towards millimeter-wave multi-antenna systems for energy-efficient and low-cost base stations for 5G wireless infrastructure. In the SILIKA Graduate School we will train 12 ESRs with - post-master level technical courses and industrial workshops which are complemented by several professional-skill training modules relevant for working in multi-disciplinary project teams. All ESRs will perform secondments in an industrial setting. - The SILIKA consortium consists of key European players in the field of wireless infrastructure with a complementary field of expertise and with a proven track-record in joint collaborations. As a consequence, SILIKA will provide the ESRs with a - comprehensive set of transferable skills relevant for innovation and long-term employability. The high level of participation of leading industries will ensure that the scientific results of SILIKA will be transferred to future products in the area - of wireless infrastructure which will benefit the European economy. - - 2020-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-EID - European Industrial Doctorates - - - Netherlands - - - SILIKA - - - H2020-MSCA-ITN-2016 - - - 721732 - - - - - UNIVERSITEIT ANTWERPEN - UNIVERSITEIT ANTWERPEN - - - EUR 1 499 250 - - - What makes leaves fall in autumn? A new process description for the timing of leaf senescence in temperate and boreal trees - - - EUR 1 499 250 - - - Belgium - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Leaf phenology is a key component in the functioning of temperate and boreal deciduous forests. The environmental cues for bud-burst in spring are well known, but little is known about the cues controlling the timing of leaf - fall in autumn. Leaf fall is the last stage of leaf senescence, a process which allows trees to recover leaf nutrients. We urgently need to understand the controls timing leaf senescence to improve our projections of forest growth and climate change. - I propose a new general paradigm of the onset of leaf senescence, hypothesizing that leaf senescence is triggered by the cessation of tree growth in autumn. I expect that: (i) in the absence of growth-limiting environmental conditions, tree growth - cessation directly controls leaf-senescence onset; and (ii) in the presence of growth-limiting conditions, photoperiod controls leaf-senescence onset – this prevents trees from starting to senesce too early. I will test these hypotheses with a - combination of: (i) manipulative experiments on young trees - these will disentangle the impact of photoperiod from that of other factors affecting tree growth cessation, namely: temperature, drought and soil nutrient availability; (ii) monitoring - leaf senescence and growth in mature forest stands; (iii) comparing the leaf senescence dynamics of four major tree species (Fagus sylvatica, Quercus robur, Betula pendula and Populus tremula) in four European locations spanning from 40º to 70º N; - and (iv) integrating the new paradigm into a model of forest ecosystem dynamics and testing it for the major forested areas of Europe. The aim is to solve the conundrum of the timing of leaf senescence in temperate and boreal deciduous trees, provide - a new interpretation of the relationship between leaf senescence, tree growth and environment, and deliver a modelling tool able to predict leaf senescence and tree growth, for projections of forest biomass production and climate change. - - 2022-01-31, ongoing project - - - 2017-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Belgium - - - LEAF-FALL - - - ERC-2016-STG - - - 714916 - - - - - WEIZMANN INSTITUTE OF SCIENCE - WEIZMANN INSTITUTE OF SCIENCE - - - EUR 150 000 - - - Elimination of Senescent Cells Approach for treatment of COPD - - - EUR 150 000 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Chronic Obstructive Pulmonary Disease (COPD) is estimated to affect up to 600 million people worldwide and by 2020 it will become the third most frequent cause of death. In Europe alone, COPD affects up to 10% of people (i.e. - more people than breast cancer and diabetes) and it takes the life of around 300,000 Europeans each year. Current therapies are associated with a variety of side effects some of which can be acute and even life threatening. Moreover, none of the - existing medications for COPD has been shown conclusively to modify the long-term decline in lung function thus, COPD remains a disease with a significant unmet medical need. - - 2018-10-31, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Israel - - - ESCAPE_COPD - - - ERC-2016-PoC - - - 727218 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - BOARD OF GOVERNORS OF THE COLORADO STATE UNIVERSITY SYSTEM - TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK - - - EUR 251 857,80 - - - To develop a novel class of metalloenzymes for application in novel asymmetric C-H activation chemistry. - - - EUR 251 857,80 - - - United Kingdom - United States - United States - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Chemical synthesis through the activation of inert C-H bonds allows scientist to efficiently assemble complex organic molecules which have specific function. We aim to develop a novel class of metalloenzymes, where a - transition metal catalyst is embedded into a genetically engineered protein, for rhodium catalysed asymmetric C-H activation reactions. We believe that the approach of incorporating a transition metal into a protein will allow for precise control of - the chemical environment around the transition metal, allowing us to control many key outcomes of the chemical reaction such as enantioselectivity, regioselectivity and reaction rates. This technology will allow for the development of C-H activation - reactions that have previously been inaccessible to the synthetic chemistry community. - - 2018-03-31, Grant Agreement terminated | - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - METENZ - - - H2020-MSCA-IF-2014 - - - 656455 - - - - - KOBENHAVNS UNIVERSITET - - - EUR 200 194,80 - - - Mechanistic and therapeutic implications of microRNA deregulation for drug resistance in bile duct cancer - - - EUR 200 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - Cholangiocarcinoma (CCA) is a dismal type of liver cancer which incidence has more than doubled the last 20 years and mortality rate in Europe alone increased 37%, reflecting the limited treatment options. In >70% of - patients CCA is unresectable due to advanced stage of disease at diagnosis, resulting in a 5% 5-year survival rate. CCA is characterized by molecular and clinical heterogeneity, complicating therapy and assessment of drug efficacy. Tumor - heterogeneity is emphasized in limited response of therapy (drug resistance) and besides genomic instability a likely consequence of deregulated pathways under control of microRNAs (miRs). Each miR can regulate multiple genes/pathways, directly - linking them to tumor heterogeneity. Deregulation of miRs can cause/control chemoresistance in other cancers, but in CCA their role is yet unclear. Thus, detailed characterization of miRs in CCA, focusing on their impact in drug resistance is - urgently needed. Hence, I have 3 specific aims of this proposal: to 1) characterize the deregulated expression pattern of miRs involved in CCA pathogenesis and integrate this data with transcriptomes obtained from matched patients; 2) determine the - role of deregulated miRs in control of chemoresistance, and 3) modulate by genome-editing key deregulated miR(s) targeting chemoresistant genes using the novel `CRISPR-Mir’ method. Achievement of these aims will yield key new insights into the role - of miRs in orchestrating CCA progression and metastasis, as well as their involvement in drug resistance. My findings will have an impact on the society and in particular in patient outcome. Dr. Andersen, a world-wide expert in the molecular - pathogenesis of CCA with a vast experience in genome medicine, will supervise the project. Successful completion of this proposal will enable me to expand my scientific expertise (plus technical and transferable skills) and to establish myself as an - independent researcher in hepatobiliary and translational research. - - 2019-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - MiRCHOL - - - H2020-MSCA-IF-2016 - - - 746068 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 183 454,80 - - - Secure information processing in quantum networks - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The promise of future quantum computers to substantially speed up computations has been advertised widely since the early days of the field. But there is a novel and fundamental aspect of devices based on quantum-mechanical - principles that has just started to be explored: Quantum computers can preserve the privacy of computations. This aspect is a distinct new advantage of quantum computers over their classical counterparts. An entire class of unprecedented computations - becomes feasible, in which the user data and the whole computation remain perfectly private – a feature impossible to achieve with classical computers. The main focus of this project is to exploit this feature and to implement secure photonic quantum - information processing in distributed quantum networks. These networks consist of clients and small-scale quantum computers connected by communication channels. Photons are chosen as they are the ideal carriers for sending information over long - distances. The clients can securely delegate computations to the quantum computers, such that neither the data nor the computation is revealed to the computers or any potential eavesdropper. The project will, first, elucidate how quantum resources - boost the security of classical computations; second, demonstrate secure quantum computations over long distances and study their verification; and third, examine practical security aspects of implementations. The research will leverage the - experimental state-of-the-art by adapting new photonic quantum technologies such as integrated photon sources and waveguide quantum circuits. Moreover, highly-efficient superconducting detectors will be applied to achieve excellent quantum control of - the photons. This research is highly innovative and will be pivotal in the researcher’s career development and for becoming an independent research group leader, as it enables acquiring both key scientific knowledge and developing complementary - skills. - - 2017-04-14, Grant Agreement terminated | - - - 2015-04-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - seQureNet - - - H2020-MSCA-IF-2014 - - - 658073 - - - - - KOBENHAVNS UNIVERSITET - - - EUR 200 194,80 - - - Development of tools to increase product yields in cyanobacteria using a synthetic biology approach - - - EUR 200 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - Cyanobacteria are versatile photosynthetic organisms that have attracted interest as a sustainable biotechnological host chassis. The toolkit for these organisms is growing fast, however, limitations such as low productivities - are still a major drawback for this emerging technology. Cynthetica will address the issue of recombinant product yields and develop two separate tools that can be universally applied for product synthesis in cyanobacteria. - - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - Cynthetica - - - H2020-MSCA-IF-2016 - - - 745959 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 170 121,60 - - - Impacts of Diseases on Wild Bird Populations - - - EUR 170 121,60 - - - Spain - - - Research Organisations - - Understanding what makes organisms ill, and the implications of diseases for dynamics and persistence of wild populations are receiving increased attention from epidemiologists, animal and public health scientists and - evolutionary biologists since diseases have major impacts on human and non-human populations. Here I propose a research that capitalizes from recent advances in disease identification, demographic modelling and advanced phylogenetic comparative - analyses to investigate the links between pathogen prevalence and life histories, demography and social behaviour of hosts. Using birds as model organisms, first I propose to investigate how prevalence of major causative agents of disease vary across - taxa with variable patterns of life history, ecology and social behaviour. Second, I aim to investigate whether prevalence of a wide range of pathogens differ between males and females, and whether these differences result from the distinct roles - they play in reproduction. Finally, I will examine whether sex differences in pathogen prevalence predict sex-specific mortality and biased sex ratios. To achieve these Objectives, I will integrate data and methodology from wildlife disease biology, - behavioural ecology and population demography. The Fellowship will enhance my analytic skills and provide training in three major fields: disease biology, comparative phylogenetic analyses and population demography. The Doñana Biological Station - (Spain) will provide a unique opportunity to acquire these skills en route to address the project Objectives, and excellent prospects for career development and interdisciplinary collaborations. In addition, the proposed project will have knock-on - benefits for biodiversity conservation by providing key knowledge on the capacities of wild birds to respond to disease threats across diverse ecosystems. - - 2019-02-28, Grant Agreement terminated - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - DisWildPop - - - H2020-MSCA-IF-2015 - - - 705334 - - - - - WEIZMANN INSTITUTE OF SCIENCE - WEIZMANN INSTITUTE OF SCIENCE - - - EUR 2 000 000 - - - Single cell genomic analysis and perturbations of hematopoietic progenitors: Towards a refined model of hematopoiesis - - - EUR 2 000 000 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Hematopoiesis is an important model for stem cell differentiation with great medical significance. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Israel - - - HemTree2.0 - - - ERC-2016-COG - - - 724471 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 183 454,80 - - - PLANAFFHO - PLANning for AFFordable HOusing - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - PLANAFFHO - PLANning for AFFordable HOusing, aims to examine how land-use planning has contributed to the provision of affordable housing for low-income people and has promoted a mix of housing tenures within new developments - in three capital cities - Copenhagen, Lisbon, and London, over the last ten years. The first aim and principal focus of the research is therefore investigating planning and housing activities in three cities (Copenhagen, Lisbon and London) that seek - to address problems of housing shortage, affordability, and segregation of housing tenures. The research aims to provide practical knowledge and innovative advice to decision-makers on what can be done regarding these huge societal challenges. The - second aim of the research, underpinning and informing the former, is to make a contribution to the theoretical and methodological advancement of international comparative research on housing and land-use planning. In order to meet these aims, the - theoretical and methodological skills of the candidate will be strengthened at the Cambridge Centre for Housing and Planning Research, located within the Department of Land Economy, University of Cambridge, and led by Professor Michael Oxley. With - over 25 years of experience and a proven track record of providing evidence and analysis to influence and support better policy and practice in several areas, the Centre is well-placed to broaden her practical experience of housing and planning - matters, from both an interdisciplinary and a comparative perspective. The research will involve short-term visits to planning departments and non-profit housing associations in Copenhagen, Lisbon, and London, aiming to contribute to a mutual - exchange of knowledge. During the visits, the candidate will collect data and conduct fieldwork. The data will be analysed though the lens of spatial and social scrutiny, an optic with which an ER with a background in geography, spatial planning, and - sociology is already familiar. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - PLANAFFHO - - - H2020-MSCA-IF-2016 - - - 747257 - - - - - UNIVERSIDAD REY JUAN CARLOS - - - EUR 170 121,60 - - - Linking plant functional diversity to ecosystem multifunctionality in arid systems worldwilde - - - EUR 170 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - The relationship between plant functional diversity and ecosystem functioning has been hotly debated, and previous research has shown direct feedbacks effects of functional community structure on ecosystem processes. However, - previous studies have not considered indirect effects via changes in biotic interactions, and this is an emerging and crucial challenge for community and ecosystem ecologists. The DRYFUN project aims to assess the ultimate effects of biotic - interactions on ecosystem processes of global drylands, by coupling a multi-trait approach with an observational database from 236 sites distributed among all continents except Antarctica. Its main objectives are to: (i) test the importance of - abiotic and biotic processes for community structure in global drylands, (ii) assess the importance of within- and between-species trait variability for functional diversity, (iii) assess both the direct and indirect impact of dryland functional - diversity on ecosystem multifunctionality (i.e., the provision of several ecosystem processes simultaneously; multifunctionality hereafter) at multiple spatial scales and (iv) explore the importance of taxonomic, functional and phylogenetic - diversities on multifunctionality. The DRYFUN project is a unique opportunity to test the universal impact of functional diversity on dryland ecosystem functioning, and to provide data for establishing relevant management and restoration strategies - for drylands. - - 2017-09-30, closed project | - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - DRYFUN - - - H2020-MSCA-IF-2014 - - - 656035 - - - - - JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN - - - EUR 171 460,80 - - - A Markedness Account of Romance Clitic Systems - - - EUR 171 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - This project deals with Romance clitic pronouns, i.e. pronominal elements that i) cannot bear primary stress and ii) may have a strong counterpart occurring in a different syntactic position. - - 2017-12-31, Grant Agreement terminated - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - MARCS - - - H2020-MSCA-IF-2014 - - - 658784 - - - - - UNIVERSITE DE PICARDIE JULES VERNE - THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN - LIMITED LIABILITY COMPANY RESEARCH AND PRODUCTION ENTERPRISE I.F. LAB - UNIVERSIDAD DE CHILE - Instituto Nacional de Higiene, Epidemiología y Microbiología - - - EUR 864 000 - - - Microelements in Life Expectancy and Aging - - - EUR 864 000 - - - France - United Kingdom - Ukraine - Chile - Cuba - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - Increased longevity with a high quality of life is desirable not only for personal life-satisfaction but also for reducing healthcare costs and for increasing the socioeconomic contributions of individuals in countries with - ageing population demographics. Lifelong lifestyle has an important impact on health status in older age and adequate nutrition plays a key role in maintaining cellular functions within normal limits. Microelements such as zinc (Zn) and copper (Cu) - are essential for life and are involved in the normal functioning of thousands of proteins. The dysregulation of these metals leads to perturbed homeostasis, disease and diminished quality of life. In this study, the molecular mechanisms by which - ageing affects Zn and Cu absorption and excretion will be determined, and the consequent impact on metal flux and transport kinetics will be expressed by mathematical modelling. The project output will include a predictive model for the impact of - ageing on Zn and Cu homeostasis, informing intervention with dietary advice or supplementation to improve longevity. The consortium combines intersectoral and interdisciplinary expertise from 3 EU and 2 partner countries with established links and - clear potential for knowledge exchange and transfer of skills. The consortium objectives are: - - 2021-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - France - - - MILEAGE - - - H2020-MSCA-RISE-2016 - - - 734931 - - - - - COLLEGE DE FRANCE - - - EUR 185 076 - - - Quantum simulation of transport properties in arbitrary shaped potential landscapes with ultracold bosonic atoms - - - EUR 185 076 - - - France - - - Higher or Secondary Education Establishments - - In solid state systems transport experiments are among the most important probes to investigate the properties of different phases of matter. A number of intriguing observations have been reported where the interaction between - the charge carriers plays a significant role. One of the most prominent examples currently explored in the laboratories are high-Tc superconductors and fractional-quantum-Hall insulators. Quantum-mechanical systems whose properties are governed by - the interaction between its constituents are computationally difficult to handle. In most cases numerical results can only be obtained for small systems or in reduced dimensions. One possibility to overcome these limitations is to perform analog - quantum simulations with ultracold atoms. The basic idea behind these experiments is to built artificial model systems using the bottom-up approach: Bosonic and fermionic atoms are cooled to ultra-low temperatures to reach quantum degeneracy. - Subsequently the atoms are confined in engineered magnetic and optical potentials realizing closed quantum systems that are, to a good approximation, decoupled from their environment. This approach has the advantage that the system parameters such as - interactions, dimensionality, geometry or the amount of disorder can be controlled externally and even varied dynamically. The rapid progress in this research area makes them promising candidates to provide stimulating input on current condensed - matter problems. It initiated a whole new field known as atomtronics, which aims at designing electronic-like circuits with potentially interesting applications. Recently developed techniques allow for an engineering of tailored trapping geometries - and high-resolution imaging, which provides new insight in the study of quantum transport. In combination with the recent success in realizing artificial magnetic fields, these techniques open the door to future studies of topological transport - phenomena. - - 2018-02-28, Grant Agreement terminated - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - BosQuanTran - - - H2020-MSCA-IF-2015 - - - 703926 - - - - - SOFTWARE IMPROVEMENT GROUP B.V - SINGULARLOGIC ANONYMI ETAIREIA PLIROFORIAKON SYSTIMATON KAI EFARMOGON PLIROFORIKIS - ATHENS UNIVERSITY OF ECONOMICS AND BUSINESS - RESEARCH CENTER - UNIVERSIDAD REY JUAN CARLOS - BITERGIUM SLL - TECHNISCHE UNIVERSITEIT DELFT - - - EUR 2 236 902,48 - - - Software ENgineering in Enterprise Cloud Applications systems - - - EUR 2 236 902,48 - - - Netherlands - Greece - Greece - Spain - Spain - Netherlands - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - The growth of cloud computing is phenomenal, with vendors experiencing yearly growth over 90%. This reflects the rate at which organizations and individuals are leaving the comfort of tried and tested solutions to move into - promising but uncharted territory. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-EID - Marie Skłodowska-Curie Innovative Training Networks (ITN-EID) - - - MSCA-ITN-EID - European Industrial Doctorates - - - Netherlands - - - SENECA - - - H2020-MSCA-ITN-2014 - - - 642954 - - - - - MUSEUM NATIONAL D'HISTOIRE NATURELLE - - - EUR 256 410 - - - Eavesdropping on the tropics: assessment of climate change impacts on amphibians through passive acoustic monitoring - - - EUR 256 410 - - - France - - - Higher or Secondary Education Establishments - - Recent climate change is a major threat for conservation of amphibian diversity, the most endangered group of vertebrates. Species distribution models derived from functional traits have been proposed to provide more robust - predictions of future climate-induced shifts in environmental suitability than commonly used correlative models. The proposed project aims, for the first time, to examine species vulnerability to climate change through a novel integration of two - scientific disciplines, bioacoustics and biogeography, thanks to the use of new tools in acoustic monitoring, signal processing and species distribution modelling. We will first explore how a key and environment-dependent behavioural trait in - amphibian anurans (i.e., reproductive calling behaviour) responds across climatic gradients and subsequently expand these findings into larger temporal and spatial scales through mechanistic approach at two levels of organisation, species and - community. The MSCA is proposed as a 3-year GF. One of the most cited research groups in ecology (UFG) will host the fellow during the outgoing phase in Brazil, where data collection, first analyses, and training in biogeography will be conducted. - The third year of return to the host organisation in France, with a leading group in bioacoustics and signal processing (MNHN), will be devoted to training in acoustic diversity indices, software development, and most transfer and dissemination - activities. The MSCA will enable the fellow to be one of the first researchers with expertise in both bioacoustics and biogeography and hence will open up the best career possibilities for him and new collaboration opportunities for the host - organisations. As the first using this novel approach, the MSCA is expected to provide advances in these two disciplines as well as to promote new scientific pathways. A series of outreach activities will also contribute to public education and - awareness of amphibian decline and climate change threats. - - 2018-12-31, Grant Agreement terminated | - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - France - - - EAVESTROP - - - H2020-MSCA-IF-2014 - - - 661408 - - - - - UNIVERSITY OF NORTHUMBRIA AT NEWCASTLE - UNIVERZA V LJUBLJANI - INSTITIUID TEICNEOLAIOCHTA BHAILE ATHA CLIATH - DUBLIN CITY UNIVERSITY - UNIWERSYTET WARSZAWSKI - POLITECHNIKA WARSZAWSKA - ELIESHA TRAINING LIMITED - FUNDACJA KREATYWNE MAZOWSZE - ISME LIMITED - Kolektor Group d.o.o., vodenje in upravljanje družb - MEDEX ZIVILSKA INDUSTRIJA DOO - KYUNGPOOK NATIONAL UNIVERSITY - CHONNAM NATIONAL UNIVERSITY - - - EUR 954 000 - - - Global Entrepreneurial Talent Management 3 - - - EUR 1 224 000 - - - United Kingdom - Slovenia - Ireland - Ireland - Poland - Poland - United Kingdom - Poland - Ireland - Slovenia - Slovenia - South Korea - South Korea - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - GETM3 – Global Entrepreneurial Talent Management 3 - focuses on young talent as a key driver of future development, developed through co-operation of 3 stakeholders: employers (inc MNC & SME’s), universities and - students/graduates. Despite a widely recognized importance of young talent (e.g. Europe 2020), its potential remains largely untapped. They are educated and entrepreneurial and yet experience instability in employment. At the same time, employers - report skills mismatch and difficulties with attracting, managing and retaining young talent. To tackle this paradoxical situation, an innovative, multi-perspective approach is needed, reinforced by our 15 partner consortium; comprising of a - transnational, inter-disciplinary, inter-generational, gender balanced and inter-sectorial research team. - - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - United Kingdom - - - GETM3 - - - H2020-MSCA-RISE-2016 - - - 734824 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - - - EUR 187 866 - - - Geography of Demography: modelling plant population responses to global habitat patterns - - - EUR 187 866 - - - Ireland - - - Higher or Secondary Education Establishments - - Mankind is profoundly altering the environments in which plant and animal populations live. An era of such massive habitat rearrangements requires ecologists to take new approaches to increase our understanding of species - distribution and likelihood of persistence worldwide. Improved ecological models of range-wide persistence and response to the simultaneous threats of climate change, habitat destruction and landscape reconfiguration are required to inform management - of biodiversity at large scales. GEODEM brings together global datasets of plant distribution and demography to gain insight into how the geographic configuration of habitats affects growth, survival and reproduction of more than 500 plant species - worldwide. The project has two main objectives: 1. Geographic Range Pattern Analysis: Using species distribution models and global spatial statistics tools to quantify and compare spatial patterns of suitable environmental conditions across species’ - biogeographic ranges. 2. Landscape Demography: Testing how the spatial arrangement of suitable habitat within the geographic space can inform population responses to environmental gradients. The fellow will be supervised by and collaborate with world - leaders in spatial ecology in Ireland and other European countries to accomplish her goals. The prestigious Marie Skłodowska-Curie fellowship will enable her to develop expertise in currently disparate areas of species distribution modelling and - demography and place her in a unique position to make significant contributions to the urgent problem of population persistence at large scales during this era of global change. It will enable the fellow to build an independent research program in - Europe after gaining research experience in top universities in Canada and Australia. - - 2017-05-31, closed project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Ireland - - - GEODEM - - - H2020-MSCA-IF-2014 - - - 658651 - - - - - GOETEBORGS UNIVERSITET - - - EUR 173 857,20 - - - Bio-physical processes around marine snow aggregates - - - EUR 173 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - Advancing our understanding of biologically driven sequestration of carbon is crucial given the rapidly increasing atmospheric CO2 concentrations. Diatoms are the most common type of phytoplankton and, as the ocean’s - biological carbon pump, a key component in this process. Diatom aggregates, in particular, comprise a significant fraction of sinking particulate matter drawing down atmospheric carbon to the depths of the ocean. Diatoms produce transparent - exopolymeric particles (TEP), a gel-like sticky sugary substance, which plays a significant role in the subsequent coagulation of diatoms into aggregates as their blooms terminate. These sinking aggregates are composed of diatoms, detritus and faecal - pellets and are so-called marine snow aggregates. - - - 2017-10-31, closed project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - BIPHA - - - H2020-MSCA-IF-2014 - - - 660481 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - - - EUR 159 900 - - - Re(search) - - - EUR 159 900 - - - Ireland - - - Higher or Secondary Education Establishments - - Re(search) will connect the citizens of Dublin with research through two fringe-festival events held in 2016 and in 2017. For each event, Dubliners will be invited to the iconic Front Square of Trinity College Dublin where - they will explore how research is addressing societal challenges (the same societal challenges laid out in H2020). The societal challenges will be explored using a range of formats including comedy, drama, dining, story-telling, and citizen-science. - These have been chosen to spark conversations between researchers and citizens on issues that matter to people’s lives. Conversations will allow citizens to construct their own views on research topics and the role of research in our society (and as - a career). Constructivist approaches to learning are known to lead to enhanced learning outcomes in formal learning settings. This proposal is based on the idea that a constructivist approach to learning can also be applied to informal learning - environments, such as Re(search) Night. - - 2017-11-30, closed project | - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.5."> - - - MSCA-NIGHT-2016 - European Researchers' Night - - - CSA - Coordination and support action - - - Ireland - - - reSEARCH - - - H2020-MSCA-NIGHT-2016 - - - 722628 - - - - - STICHTING NIOZ, KONINKLIJK NEDERLANDS INSTITUUT VOOR ONDERZOEK DER ZEE - - - EUR 165 598,80 - - - Electrogenic NItrate Reduction In marine Sediments - - - EUR 165 598,80 - - - Netherlands - - - Research Organisations - - Recently, a novel type of long, filamentous bacteria has been discovered, which are capable of guiding electrical currents over centimeter distances. These so-called “cable bacteria” were first isolated from marine sediments, - and laboratory experiments demonstrate that electrons are passed on from cell to cell along the longitudinal axis of the filaments. This long-distance electron transport radically extends the physiological capacities of prokaryotes, and profoundly - changes our understanding of biogeochemical transformations in marine sediments. - - - 2018-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - ENIRIS - - - H2020-MSCA-IF-2014 - - - 656385 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - - - EUR 1 860 008,75 - - - SHARECITY: Assessing the practice and sustainability potential of city-based food sharing economies - - - EUR 1 860 008,75 - - - Ireland - Ireland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - With planetary urbanization fast approaching there is growing clarity regarding the unsustainability of cities, not least with respect to food consumption. Sharing, including food sharing, is increasingly being identified as - one transformative mechanism for sustainable cities: reducing consumption; conserving resources, preventing waste and providing new forms of socio-economic relations. However, such claims currently rest on thin conceptual and empirical foundations. - SHARECITY will identify and examine diverse practices of city-based food sharing economies, first determining their form, function and governance and then identifying their impact and potential to reorient eating practices. The research has four - objectives: to advance theoretical understanding of contemporary food sharing economies in cities; to generate a significant body of comparative and novel international empirical knowledge about food sharing economies and their governance within - global cities; to design and test an assessment framework for establishing the impact of city-based food sharing economies on societal relations, economic vitality and the environment; and to develop and implement a novel variant of backcasting to - explore how food sharing economies within cities might evolve in the future. Providing conceptual insights that bridge sharing, social practice and urban transitions theories, SHARECITY will generate a typology of food sharing economies; a database - of food sharing activities in 100 global cities; in-depth food sharing profiles of 7 cities from the contrasting contexts of USA, Brazil and Germany, Greece, Portugal, Ireland and Australia; a sustainability impact toolkit to enable examination of - city-based food sharing initiatives; and scenarios for future food sharing in cities. Conducting such frontier science SHARECITY will open new research horizons to substantively improve understanding of how, why and to what end people share food - within cities in the 21st Century. - - 2020-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Ireland - - - SHARECITY - - - ERC-2014-CoG - - - 646883 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - - - EUR 1 521 875 - - - Frontier research in arterial fibre remodelling for vascular disease diagnosis and tissue engineering - - - EUR 1 521 875 - - - Ireland - Ireland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Each year cardiovascular diseases such as atherosclerosis and aneurysms cause 48% of all deaths in Europe. Arteries may be regarded as fibre-reinforced materials, with the stiffer collagen fibres present in the arterial wall - bearing most of the load during pressurisation. Degenerative vascular diseases such as atherosclerosis and aneurysms alter the macroscopic mechanical properties of arterial tissue and therefore change the arterial wall composition and the quality and - orientation of the underlying fibrous architecture. Information on the complex fibre architecture of arterial tissues is therefore at the core of understanding the aetiology of vascular diseases. The current proposal aims to use a combination of in - vivo Diffusion Tensor Magnetic Resonance Imaging, with parallel in silico modelling, to non-invasively identify differences in the fibre architecture of human carotid arteries which can be directly linked with carotid artery disease and hence used to - diagnose vulnerable plaque rupture risk. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Ireland - - - FibreRemodel - - - ERC-2014-STG - - - 637674 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - - - EUR 1 447 410 - - - Plasmonic Enhancement and Directionality of Emission for Advanced Luminescent Solar Devices - - - EUR 1 447 410 - - - Ireland - Ireland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Applying photovoltaic (PV) panels to buildings is an important application for wider PV deployment and to achieving our 20% Renewable Energy EU targets by 2020. PEDAL will develop a disruptive PV technology where record - increases in efficiency are achieved and costs dramatically reduced; - - - 2020-03-31, ongoing project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Ireland - - - PEDAL - - - ERC-2014-STG - - - 639760 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - - - EUR 1 499 865 - - - Late First-Row Transition Metal-Oxo Complexes for C–H Bond Activation - - - EUR 1 499 865 - - - Ireland - Ireland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The chemical, pharmaceutical, and materials industries rely heavily upon chemicals from oil and natural gas feed-stocks (saturated hydrocarbons) that require considerable functionalisation prior to use. Catalytic oxidative - functionalisation (e.g. CH4 + [O] + cat. → CH3OH), using first row transition metal catalysts, is potentially a sustainable, cheap, and green route to these high-commodity chemicals. However, catalytic oxidation remains a great modern challenge - because such hydrocarbons contain remarkably strong inert C–H bonds that can only be activated with potent catalysts. We will take a Nature-inspired approach to designing and preparing powerful oxidation catalysts: we will interrogate the active - oxidant, a metal-oxo (M=O) species, to guide our catalyst design. Specifically, we will prepare unprecedented Late first-row transition Metal-Oxo complexes (LM=O’s, LM = Co, Ni, Cu) that will activate the strongest of C–H bonds (e.g. CH4). - - - 2021-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Ireland - - - HurdlingOxoWall - - - ERC-2015-STG - - - 678202 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - INSTITUT ZA FIZIKU - TECHNISCHE UNIVERSITEIT DELFT - SENZOR INFIZ DOO - FUNDACIO INSTITUT CATALA DE NANOCIENCIA I NANOTECNOLOGIA - KATHOLIEKE UNIVERSITEIT LEUVEN - - - EUR 769 500 - - - Designing Advanced Functionalities through controlled NanoElement integration in OXide thin films - - - EUR 769 500 - - - Spain - Serbia - Netherlands - Serbia - Spain - Belgium - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - - The aim of this project is to develop new inexpensive, scalable and efficient bottom –up approach for positioning nanoobjects in regular patterns and to implement them in optoelectronic technology, which is the major challenge - in nanotechnology today. The synergy between the quasi zero-dimensional elements and functional oxides with an exceptional range of properties (ferromagnetism, ferroelectricity, …) opens a completely new concept to nanoelectronics. Devices based on - these materials would offer functionality beyond the achievable limits, with wide range of applications from spintronics and catalytics to optoelectronics. - - 2018-06-30, ongoing project | - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Spain - - - DAFNEOX - - - H2020-MSCA-RISE-2014 - - - 645658 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - - - EUR 187 866 - - - Quantum Entanglement And Holography - - - EUR 187 866 - - - Ireland - - - Higher or Secondary Education Establishments - - Entanglement Entropy and other measures of quantum entanglement have recently given great insights into the physics of both quantum field theories and gravity. - - - 2017-08-31, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Ireland - - - QEAH - - - H2020-MSCA-IF-2014 - - - 659151 - - - - - UNIVERSITY COLLEGE LONDON - UNIVERSITY OF BRISTOL - - - EUR 183 454,80 - - - Insect social parasites: behavioural genomics models for understanding the basis of phenotypic evolution - - - EUR 183 454,80 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Understanding how diversity of life arises at the level of the genes is one of the biggest challenges in modern biology. Genomic methodologies now allow us to dissect the molecular basis of this phenotypic diversity and - plasticity. However, we lack an integrated study of key phenotypic traits and their dynamic changes in an ecologically relevant setting, with the associated dynamic nature of the underpinning genes. I propose to use an inter-disciplinary approach, by - uniting classical ethology with new molecular tools of genomics, to understand how genes give rise to phenotypic traits and their dynamic plasticity using an insect social parasite system as model. Insect social parasites show striking phenotypic - diversity compared to their hosts and have been identified as unique models for understanding the molecular basis of phenotypic diversity and plasticity. Yet, they have remained largely unexploited so far, due to the difficulty of conducting genomic - studies on non-model organisms. This project will combine for the first time the transcriptomic (i.e. multiple species comparisons of brain genome-wide RNA-seq analyses followed by candidate gene approach RT-PCR) and behavioural phenotyping in order - to reveal the molecular basis of phenotypic diversity in a Polistes paper wasp social parasite system, which comprises the social parasite, the host and a related non host species. This will be a landmark project in the exploding field of Behavioural - Genomics as it will ensure high replication in an ecologically relevant setting in wild populations and it will exploit a deep ethological knowledge of the model system to ensure precise integration of behaviour with new methods for dissecting - molecular processes. This project offers a unique opportunity to capitalize on molecular and behavioural expertise of the Supervisor and ER, generating the most comprehensive empirical and theoretical body of work to date, thus placing the ER as a - leader in this new and exciting field. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SocParPhenoEvol - - - H2020-MSCA-IF-2015 - - - 706208 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - - - EUR 1 806 536 - - - Western banks in Eastern Europe: New geographies of financialisation - - - EUR 1 806 536 - - - Ireland - Ireland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Financialisation, or the growing power of finance over societies and economies, is increasingly recognised as the key feature of contemporary capitalism. However, significant gaps in our understanding of this process remain. - Indeed, despite growing recognition that financialisation is an inherently spatial process, a geographically-informed view of financialisation remains underdeveloped. In addition, and related to this, the extent and the ways in which post-socialist - ‘transition’ societies in East-Central Europe have been financialised remain under-researched and under-theorised. Yet, the examination of former state-socialist societies (built on the very opposite economic logic to that of financialisation) - provides an unmatched opportunity to learn about financialisation itself, how it ‘penetrates’ societies and with what social and spatial implications. East-Central Europe in this sense constitutes a unique terrain for frontier research. GEOFIN will - address the above shortcomings by producing empirical and theoretical insights to develop a geographically-informed view of financialisation. The objective is to examine how states, banks and households in post-socialist contexts have been - financialised and to consider what implications this has for the societies in question and for Europe as a whole. The project will pilot a novel approach based on the concept of ‘financial chains’ which are understood both as channels of value - transfer and as social relations that shape socio-economic processes and attendant economic geographies. A set of interlocking case studies will be mobilised to reveal the different ways in which banks, states and households across post-socialist - East-Central Europe are interconnected by financial chains with each other and with a wider political economy. GEOFIN will fundamentally advance our understanding of new geographies of financialisation, opening up new horizons in studies of finance - and its future role in the society. - - 2021-11-30, ongoing project - - - 2016-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Ireland - - - GEOFIN - - - ERC-2015-CoG - - - 683197 - - - - - UNIVERSIDAD REY JUAN CARLOS - UNIVERSIDAD REY JUAN CARLOS - - - EUR 1 894 450 - - - Biological feedbacks and ecosystem resilience under global change: a new perspective on dryland desertification - - - EUR 1 894 450 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Changes in climate and land use (e.g., increased grazing pressure), are two main global change components that also act as major desertification drivers. Understanding how drylands will respond to these drivers is crucial - because they occupy 41% of the terrestrial surface and are home to over 38% of the world’s human population. Land degradation already affects ~250 million people in the developing world, which rely upon the provision of many ecosystem processes - (multifunctionality). This proposal aims to develop a better understanding of the functioning and resilience of drylands (i.e. their ability to respond to and recover from disturbances) to major desertification drivers. Its objectives are to: 1) test - how changes in climate and grazing pressure determine spatiotemporal patterns in multifunctionality in global drylands, 2) assess how biotic attributes (e.g., biodiversity, cover) modulate ecosystem resilience to climate change and grazing pressure - at various spatial scales, 3) test and develop early warning indicators of desertification, and 4) forecast the onset of desertification and its ecological consequences under different climate and grazing scenarios. I will use various biotic - communities/attributes, ecosystem services and spatial scales (from local to global), and will combine approaches from several disciplines. Such comprehensive and highly integrated research endeavor is novel and constitutes a ground breaking advance - over current research efforts on desertification. This project will provide a mechanistic understanding on the processes driving multifunctionality under different global change scenarios, as well as key insights to forecast future scenarios for the - provisioning of ecosystem services in drylands, and to test and develop early warning indicators of desertification. This is of major importance to attain global sustainability and key Millennium Development Goals, such as the eradication of poverty. - - 2020-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Spain - - - BIODESERT - - - ERC-2014-CoG - - - 647038 - - - - - UNIVERSIDAD DE BURGOS - - - EUR 170 121,60 - - - Novel Nanoporous PZT Materials for Efficient Utrasonic Biomedical Sensors - - - EUR 170 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - Piezoelectric materials have become a key technology for a wide range of industrial and consumer products with a robust global market of U.S. $21 billion in the last 2013. Current technology includes applications on actuators, - ultrasonic motors, sensor arrays for structural health monitoring, transformers, micro-energy harvesting devices, hydrophones, high resolution ultrasonic medical imaging, computer disk drives, and accelerometers in mobile phones and notebooks. - Currently the most important piezoelectric ceramic materials are based on mixed oxide crystal system consisting of lead, zirconium and titanium, well known as lead zirconate titanate (PZT). Cost-effective and efficient synthetic strategies, - structural modifications and doping by foreign ions represent the key steps to significantly improve the performance of PZT materials, such as piezoelectric, dielectric and mechanical stability properties. In this frame, we purpose a new research - methodology based on the preparation, characterization and testing of hierarchical porous PZT-doped using alternative synthetic approaches (EISA method) and new doping materials (porous Mg-Niobate, Graphene/Molybdenite and Nanocellulose) to achieve - important innovations and overcome the current state of art on the field of hydrophones and high resolution ultrasonic medical applications. Innovations are represented by the preparation of highly-efficient porous PZT matrices, not yet reported in - the literature, with very-high surface area whit the idea to enhance the contact between PZT-matrix and media (water, medical gels, etc) and then increasing the sensibility and piezoelectric response of the device. Regarding new doping approaches, - Nb-source will be nano-confined into the PZT matrices using the pores as hosting elements with the advantage of constraining dopants in nanoscale. Graphene/Molybdenit nanocomposite and Nanocellulose will be also used to replace critical Nb as also - recently recommend by the European guidelines. - - 2018-11-01, ongoing project - - - 2016-11-02 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - Nano-PieZoelecTrics - - - H2020-MSCA-IF-2015 - - - 707954 - - - - - UNIVERZA V LJUBLJANI - UNIVERZA V LJUBLJANI - - - EUR 2 041 000 - - - Open Many-body Non-Equilibrium Systems - - - EUR 2 041 000 - - - Slovenia - Slovenia - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - We shall study non-equilibrium many-body quantum systems, considering local interactions in one or two spatial dimensions in situations where the generator of time evolution in the bulk of the system is unitary whereas the - incoherent processes are limited to the system's boundaries. We foresee a mathematical theory of dynamical quantum phases of matter with applications in the theory of quantum transport and nanoscale devices that manipulate heat, information, charge - or magnetization. - - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Slovenia - - - OMNES - - - ERC-2015-AdG - - - 694544 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - - - EUR 1 382 642,50 - - - The Neural Determinants of Perceptual Decision Making in the Human Brain - - - EUR 1 382 642,50 - - - Ireland - Ireland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - How do we make reliable decisions given sensory information that is often weak or ambiguous? Current theories center on a brain mechanism whereby sensory evidence is integrated over time into a “decision variable” which - triggers the appropriate action upon reaching a criterion. Neural signals fitting this role have been identified in monkey electrophysiology but efforts to study the neural dynamics underpinning human decision making have been hampered by technical - challenges associated with non-invasive recording. This proposal builds on a recent paradigm breakthrough made by the applicant that enables parallel tracking of discrete neural signals that can be unambiguously linked to the three key information - processing stages necessary for simple perceptual decisions: sensory encoding, decision formation and motor preparation. Chief among these is a freely-evolving decision variable signal which builds at an evidence-dependent rate up to an - action-triggering threshold and precisely determines the timing and accuracy of perceptual reports at the single-trial level. This provides an unprecedented neurophysiological window onto the distinct parameters of the human decision process such - that the underlying mechanisms of several major behavioral phenomena can finally be investigated. This proposal seeks to develop a systems-level understanding of perceptual decision making in the human brain by tackling three core questions: 1) what - are the neural adaptations that allow us to deal with speed pressure and variations in the reliability of the physically presented evidence? 2) What neural mechanism determines our subjective confidence in a decision? and 3) How does aging impact on - the distinct neural components underpinning perceptual decision making? Each of the experiments described in this proposal will definitively test key predictions from prominent theoretical models using a combination of temporally precise - neurophysiological measurement and psychophysical modelling. - - 2020-04-30, ongoing project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Ireland - - - Human Decisions - - - ERC-2014-STG - - - 638289 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - - - EUR 1 428 342,50 - - - Prisons: the Rule of Law, Accountability and Rights - - - EUR 1 428 342,50 - - - Ireland - Ireland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - PRILA will create the first account of how mechanisms for securing rights, ensuring accountability and achieving adherence to the rule of law are experienced in European prisons. Prisons are places where considerable power - differentials exist, and are unique sites for the expression of the values which underpin public and prison law. Systems to ensure that prisoners are treated fairly and that rights are upheld are essential to ensure that imprisonment is conducted in - ways that are just and promote good order. These are fundamental principles of the ‘European’ way in penal policy and penal law. Existing accounts of the deployment of penal power overlook key elements of how accountability, the rule of law, and - rights are experienced. PRILA will document how prisoners, prison staff, staff of accountability bodies experience structures for ensuring decisions and actions taken in prison are fair, transparent, consistent, subject to appeal and review, and in - compliance with principles of human rights. In doing so, PRILA will transform and extend accounts of legitimacy in prisons, judicial review of administrative action, the pains of imprisonment, and understandings of how penal power is experienced. - Drawing on the disciplines of public and prison law, human rights, comparative law, and the sociology of punishment, the project will utilise legal, qualitative and quantitative research methods to create an account of how ‘accountability work’ is - experienced. It will also examine how accountability structures are manifestations of penal ideologies or types of prison regimes. The project will advance current judicial and legal conceptions of accountability, the rule of law, and fairness, by - reference to how these concepts are experienced in practice, and examine whether and how they are distinctively ‘European’. The project will thereby support the creation of better penal policies and practices aimed at the protection of the rule of - law and rights in the prison context. - - 2021-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Ireland - - - PRILA - - - ERC-2015-STG - - - 679362 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - - - EUR 1 954 065,02 - - - Loop amplitudes in quantum field theory - - - EUR 1 954 065,02 - - - Ireland - Ireland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The traditional formulation of relativistic quantum theory is ill-equipped to handle the range of difficult computations needed to describe particle collisions at the Large Hadron Collider (LHC) within a suitable time frame. - Yet, recent work shows that probability amplitudes in quantum gauge field theories, such as those describing the Standard Model and its extensions, take surprisingly simple forms. The simplicity indicates deep structure in gauge theory that has - already led to dramatic computational improvements, but remains to be fully understood. For precision calculations and investigations of the deep structure of gauge theory, a comprehensive method for computing multi-loop amplitudes systematically and - efficiently must be found. - - 2020-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Ireland - - - CutLoops - - - ERC-2014-CoG - - - 647356 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - - - EUR 1 804 052 - - - Targeting iNKT cell and adipocyte crosstalk for control of metabolism and body weight - - - EUR 1 804 052 - - - Ireland - Ireland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Obesity has reached epidemic proportions globally. At least 2.8 million people die each year as a result of being overweight or obese, the biggest burden being obesity-related diseases. It is now clear that inflammation is an - underlying cause or contributor to many of these diseases, including type 2 diabetes, atherosclerosis, and cancer. Recognition that the immune system can regulate metabolic pathways has prompted a new way of thinking about diabetes and weight - management. Despite much recent progress, most immunometabolic pathways, and how to target them, are currently unknown. One such pathway is the cross-talk between invariant natural killer (iNKT) cells and neighboring adipocytes. iNKT cells are the - innate lipid-sensing arm of the immune system. Since our discovery that mammalian adipose tissue is enriched for iNKT cells, we have identified a critical role for iNKT cells in regulating adipose inflammation and body weight. The goal of this - project is to use a multi-disciplinary approach to identify key signals and molecules used by iNKT cells to induce metabolic control and weight loss in obesity. Using immunological assays and multi-photon intravital microscopy, cells and pathways - that control the unique regulatory functions of adipose iNKT cells will be identified and characterised. Novel lipid antigens in adipose tissue will be identified using a biochemical approach, perhaps explaining iNKT cell conservation in adipose - depots, and providing safe tools for iNKT cell manipulation in vivo. Finally, using proteomics and whole body metabolic analysis in vivo, novel ‘weight-loss inducing’ factors produced by adipose iNKT cells will be identified. This ambitious and high - impact project has the potential to yield major insights into immunometabolic interactions at steady state and in obesity. The ability to activate or induce adipose iNKT cells holds remarkable potential as an entirely new therapeutic direction for - treating obesity and type 2 diabetes. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Ireland - - - FAT NKT - - - ERC-2015-STG - - - 679173 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - - - EUR 2 213 316,88 - - - Tuneable 2D Nanosheet Networks for Printed Electronics - - - EUR 2 213 316,88 - - - Ireland - Ireland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In the future, even the most mundane objects will contain electronic circuitry allowing them to gather, process, display and transmit information. The resulting vast network, often called the Internet of Things, will - revolutionise society. To realise this will require the ability to produce electronic circuitry extremely cheaply, often on unconventional substrates. This will be achieved through printed electronics, by the assembly of devices from solution (i.e. - ink) using methods adapted from printing technology. However, while printed electronics has been advancing rapidly, the development of new, nano-materials-based inks is required for this area to meet its true potential. - - 2021-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Ireland - - - FUTURE-PRINT - - - ERC-2015-AdG - - - 694101 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - - - EUR 187 866 - - - Controlled Singlet Oxygen Release Photosensitizers in Photodynamic Therapy - - - EUR 187 866 - - - Ireland - - - Higher or Secondary Education Establishments - - Photodynamic therapy is a form of phototherapy which uses light-sensitive compounds (photosensitizers) that are exposed selectively to light, whereupon they become toxic to targeted malignant and other diseased cells. The - photosensitizer creates a highly reactive singlet oxygen species which rapidly reacts with any nearby biomolecules leading to destructive reactions resulting in cell death through apoptosis or necrosis. However, prolonged exposure of tissue to light - irradiation causes photosensitivity in patients’ skin. Side effects may include, pain, burning/stinging sensation, itchiness. This proposal aims to develop a conceptually new approach towards photodynamic therapy through an introduction of new type - of photosensitizers and corresponding nanomaterials which are capable to generate singlet oxygen upon irradiation, store it by means of binding to special molecular subunits and slowly release singlet oxygen within tissue on a timescale from several - hours to several days after light irradiation treatment. The application of such novel material will allow for increasing therapeutic effect and reduced side-effects with respect to conventional PDT due to shorter light treatment duration. Proof of - concept will be attained by demonstration of delayed singlet oxygen formation in cancer cells after the light treatment using in vitro models. The project builds on the strengths of the applicant in organic chemistry, photophysics and material - science and combines these with new training in biomedicine and drug development to open a new research direction and to enhance cross-European collaboration. - - 2017-09-14, closed project - - - 2015-09-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Ireland - - - CONSORT - - - H2020-MSCA-IF-2014 - - - 655142 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - - - EUR 1 498 734 - - - Engineering a scaffold based therapy for corneal regeneration - - - EUR 1 498 734 - - - Ireland - Ireland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Corneal blindness resulting from disease, physical injury or chemical burns affects millions worldwide and has a considerable economic and social impact on the lives of people across Europe. In many cases corneal transplants - can restore vision however the shortage of donor corneas suitable for transplantation has necessitated the development of alternative treatments. The aim of this project is to develop a new approach to corneal tissue regeneration. Previous approaches - at engineering corneal tissue have required access to donor cells and lengthy culture periods in an attempt to grow tissue in vitro prior to implantation with only limited success and at great expense. Our approach will differ fundamentally from - these in that we will design artificial corneal scaffolds that do not require donated cells or in vitro culture but instead will recruit the patient’s own cells to regenerate the cornea post-implantation. These biomaterial scaffolds will incorporate - specific chemical and physical cues with the deliberate aim of attracting cells and inducing tissue formation. Studies will be undertaken to examine how different chemical, biochemical, physical and mechanical cues can be used to control the - behaviour of corneal epithelial, stromal and endothelial cells. Once the optimal combination of these cues has been determined, this information will be incorporated into the design of the scaffold. Recent advances in manufacturing and material - processing technology will enable us to develop scaffolds with organized nanometric architectures and that incorporate controlled growth factor release mechanisms. Techniques such as 3D bio-printing and nanofiber electrospinning will be used to - fabricate scaffolds. The ability of the scaffold to attract cells and promote matrix remodelling will be examined by developing an in vitro bioreactor system capable of mimicking the ocular environment and by performing in vivo tests using a live - animal model. - - 2020-06-30, ongoing project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Ireland - - - EyeRegen - - - ERC-2014-STG - - - 637460 - - - - - UNIVERSITA' DEGLI STUDI DI SIENA - UNIVERSITA' DEGLI STUDI DI SIENA - - - EUR 2 500 000 - - - Origins of a new Economic Union (7th to 12th centuries): resources, landscapes and political strategies in a Mediterranean region - - - EUR 2 500 000 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Medieval archaeology over the past thirty years has challenged the canonic history of the rise of Western Europe. First, the collapse of the Roman world in Italy by the 7th century was more profound than had been previously - envisaged by historians, leaving rural society, in particular, maintaining comparatively primitive conditions. Secondly, in complete contrast, north-west Europe by stages between the 7th and 9th centuries developed an integrated economic union. - Central to this was agricultural intensification coupled with strategic deployment of a silver currency. Thirdly, between the 9th and 12th centuries certain regions of Italy, drawing simultaneously upon connections to the north as well as the - Mediterranean, became the economic and political motor of the new Medieval Europe, paving the way for the Renaissance. - - - 2020-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Italy - - - nEU-Med - - - ERC-2014-ADG - - - 670792 - - - - - GENOME RESEARCH LIMITED - GENOME RESEARCH LIMITED - EUROPEAN MOLECULAR BIOLOGY LABORATORY - - - EUR 1 980 685 - - - Re(defining) CD4+ T Cell Identities One Cell at a Time - - - EUR 1 980 685 - - - United Kingdom - United Kingdom - Germany - - - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The immune system consists of a complex continuum of cell types that communicate with each other and non-immune tissues in homeostasis, and during infections, autoimmunity and cancer. Conventional transcriptional and - functional profiling enabled by cell surface marker sorting has revealed a great deal about how specific cell types operate en masse, yet important transcriptional heterogeneity that exists within cell populations remains unexplored. High-throughput - single cell RNA-seq can overcome this limitation by profiling entire transcriptomes of thousands of individual cells, revealing cell-to-cell variation by decoding patterns within populations masked in bulk transcriptomes. We will exploit this to - dissect the mouse CD4+ T cell compartment, a heterogeneous white blood cell population that initiates adaptive immune responses. - - 2020-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - ThDEFINE - - - ERC-2014-CoG - - - 646794 - - - - - UNIVERSIDAD DE LA LAGUNA - UNIVERSIDAD DE LA LAGUNA - - - EUR 1 996 750 - - - PALEOCHAR: Insights into the Neanderthals and their demise from the study of microscopic and molecular charred matter in Middle Palaeolithic sediments - - - EUR 1 996 750 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Who were the Neanderthals and what caused their demise? To answer these questions, the classic approach in archaeology relies on the analysis of the Neanderthals' stone-tool assemblages and the mineralized bone remains of - their dietary intake. Although this approach has yielded a great deal of important information about the Neanderthals’ fate, it is also limited in the sense that the only evidence that is considered is in-organic in nature. In the current proposal, - we attempt to answer these questions by considering microscopic and molecular evidence that is organic in nature. By studying the organic sedimentary record at such fine scales, we are able to extract information about, for example, the fat contents - of the Neanderthal food, the way they made fire, the arrangements of their living spaces, their surrounding vegetation and the climatic conditions where they lived. By combining these different sources of information we aim to provide a more complete - picture of the Neanderthals and the reason of their disappearance. - - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Spain - - - PALEOCHAR - - - ERC-2014-CoG - - - 648871 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - - - EUR 175 866 - - - Neuroscience and Narratives of Intimacy - - - EUR 175 866 - - - Ireland - - - Higher or Secondary Education Establishments - - As human beings, we tend to connect. Yet social isolation is a widespread condition with grave consequences on life-expectancy. Ideals of self-sufficiency and new modes of communication incite to isolate rather than attach. By - contrast, experiencing meaningful intimate interactions has positive effects on health. But what is intimacy, where is it to be found, has it changed and how can it be studied? - - 2018-05-14, ongoing project - - - 2016-05-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Ireland - - - NNI - - - H2020-MSCA-IF-2015 - - - 705283 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - - - EUR 187 866 - - - Historical Dynamics of Violence, Conflict and Extreme Weather in Medieval Ireland - - - EUR 187 866 - - - Ireland - - - Higher or Secondary Education Establishments - - This project draws upon historical, palaeoclimatic, palaeoecological and archaeological records to examine the role of extreme weather in the occurrence of violence and conflict in medieval Ireland. The research is founded - upon the Irish Annals, which preserve a detailed record of violence and conflict as chronicled by monastic scribes from the sixth to thirteenth centuries and, thereafter to the seventeenth century, by hereditary historians employed by the Irish - nobility. The Irish oak tree-ring record provides a means of identifying years of extreme wetness and dryness, while Greenland ice-core records furnish evidence for major volcanic eruptions that often caused extreme cold. Combining these diverse - sources affords an important opportunity to examine whether extreme weather meaningfully influenced violence and conflict in a complex agrarian society for over a millennium. To identify the mechanisms that may link extreme weather to violence and - conflict, insights will be drawn from written sources such as the Irish law texts, hagiographical texts and bardic poetry. The rich record of weather extremes, societal impacts and coping mechanisms provided by the Irish Annals themselves will also - be exploited. Climate-conflict linkages are also likely to be mediated by changing background socioeconomic and climatic conditions that promote varying societal resilience to extreme weather. Diverse palaeoclimatic, archaeological and - palaeoecological evidence will thus be employed to track the often dramatic changes in Irish agricultural and military technology, in settlement and political structures, and in average precipitation and temperatures, experienced across this long - period of Irish history. - - 2018-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Ireland - - - CLIMCONFLICT - - - H2020-MSCA-IF-2015 - - - 709185 - - - - - UNIVERSIDAD REY JUAN CARLOS - - - EUR 239 191,20 - - - Climatic and temporal control on microbial diversity-ecosystem functioning: insights from a novel conceptual model (CLIMIFUN). - - - EUR 239 191,20 - - - Spain - - - Higher or Secondary Education Establishments - - Despite the importance of soil microbial communities for ecosystem functioning and human welfare, little is known about the mechanisms controlling the composition and diversity of these communities, and the role of their - attributes in providing multiple ecosystem functions and services such as nutrient cycling and decomposition (i.e. multifunctionality). Many studies have identified climate, stage of ecosystem development and soil characteristics as main drivers of - plant and animal diversity. However, much less is known about the interactive effects of climate, soil properties and time in controlling microbial diversity and multifunctionality during ecosystem succession. This lack of knowledge hampers our - ability to predict microbial community shifts and their consequences for ecosystem functioning under climate change, and limits the inclusion of soil microbes in global biogeochemical models. The main research objective of this action is to gain a - deeper insight into the patterns and mechanisms that drive soil microbial diversity and multifunctionality under changing environments. We will use a novel conceptual framework combining long-term chronosequences, climate change experiments and - structural equation modelling to quantitatively evaluate the role of time, climate and multiple soil drivers in controlling microbial diversity and multifunctionality. The research outlined in this proposal includes a range of state-of-the-art - biochemical, molecular and genomic methods for the analysis of microbial communities and multifunctionality that ensure the maximum utility and impact of our results. Altogether, CLIMIFUN will reveal the factors that control soil microbial diversity - and multiple functions linked to plant production and nutrient cycling under a changing environment. This work will thus address a key knowledge gap relevant to supporting increases in global demand for food and fibre over the next decades, and a - research priority for H2020. - - 2019-07-31, ongoing project - - - 2016-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Spain - - - CLIMIFUN - - - H2020-MSCA-IF-2015 - - - 702057 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - - - EUR 248 063,40 - - - Use of novel techniques to identify pathogenic versus non-pathogenic TH17 cells in experimental autoimmune encephalomyelitis, a murine model of multiple sclerosis. - - - EUR 248 063,40 - - - Ireland - - - Higher or Secondary Education Establishments - - The aim of this Fellowship is for the researcher, Dr Karen Dixon, to receive advanced training, develop interdisciplinary skills with high-impact dissemination, and practical experience in line with a leading independent - researcher in the EU. The remit of the Fellowship proposal falls under the category of Immunology- autoimmunity and TH17 cell biology. The researcher will be based for two years in the laboratory of Professor Vijay Kuchroo at Brigham & Women`s - Hospital. The third year of the Fellowship will be completed in the Department of Biochemistry & Immunology, Trinity College Dublin (TCD) working under the supervision of Professor Kingston Mills. Research training will be implemented through an - interdisciplinary project investigating the mechanism by which IL-23 regulates the development of pathogenic vs non-pathogenic TH17 cells. On the outgoing phase of the Fellowship, the researcher will access expertise, state-of-the-art training and - mentoring in deciphering the heterogeneity of TH17 cells using advanced transcriptional analysis. In the return phase the researcher will consolidate the knowledge and experience gained in the US through further laboratory training in IL-17 mediated - disease. In TCD she will be given the opportunity to embed her new knowledge in Ireland through mentoring and teaching in the host institute. This includes practical seminars on state of the art technology including single cell RNA-seq and NanoString - technology. Under the guidance of international experts, she will acquire an invaluable skillset using the latest technical advances to decode heterogeneous populations in immune mediated diseases. The resources of the host departments will - facilitate development of an interdisciplinary and international academic network as well as career-mentoring. With increasing recognition of the functional heterogeneity within cell populations, this Fellowship will establish the researcher firmly - at the centre of immunological research in the EU. - - 2019-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Ireland - - - DANTE - - - H2020-MSCA-IF-2015 - - - 708658 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - - - EUR 2 499 265 - - - North Atlantic Fisheries: An Environmental History, 1400-1700 - - - EUR 2 499 265 - - - Ireland - Ireland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - NorFish aims to understand the restructuring of the North Atlantic fisheries, fish markets and fishery-dependent communities in the late medieval and early modern world. The project exploits a multi-disciplinary, - humanities-led approach to marine environmental history, assessing and synthesizing the dynamics and significance of the North Atlantic fish revolution, equipped by methodological advances in which the PI has been to the fore in delivering. It - establishes a robust quantitative framework of extractions, supplies and prices, while also charting the qualitative preferences and politics that motivated actors of the fish revolution across the North Atlantic. - - - 2020-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Ireland - - - NorFish - - - ERC-2014-ADG - - - 669461 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - - - EUR 2 499 942 - - - 3D Printing of Novel 2D Nanomaterials: Adding Advanced 2D Functionalities to Revolutionary Tailored 3D Manufacturing - - - EUR 2 499 942 - - - Ireland - Ireland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - My vision is to establish, within the framework of an ERC CoG, a multidisciplinary group which will work in concert towards pioneering the integration of novel 2-Dimensional nanomaterials with novel additive fabrication - techniques to develop a unique class of energy storage devices. - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Ireland - - - 3D2DPrint - - - ERC-2015-CoG - - - 681544 - - - - - UNIVERSIDAD DE LA LAGUNA - - - EUR 251 276,40 - - - Tracking past human impact on islands by improving palaeoecological reconstructions with PalEnDNA analysis - - - EUR 251 276,40 - - - Spain - - - Higher or Secondary Education Establishments - - Island ecosystems host a significant proportion of global biodiversity, but their rich insular biotas are also more vulnerable and less resistant to novel pressures than continental biotas. Human colonization has been a - relatively recent event on most islands globally, and has nearly always resulted in devastating losses of biodiversity. The Canary Islands were no exception; these oceanic islands were colonized by aborigines more than 2000 years ago and later by - Europeans, and have been transformed since this time. Despite being one of the most biodiverse regions within Europe and a target for EU biodiversity policies, there is a key knowledge gap about the pre-human state and natural variability of - unmodified Canarian ecosystems that could help planners and managers to guide their strategies. This makes the Canaries the perfect place to reconstruct baseline ecosystem states and the long-term impacts of human activities. ISLANDPALECO will assess - the timing and extent of human impact on Canary Island ecosystems by providing detailed reconstructions of past environments, combining leading edge and conventional palaeoecological tools and integrating the results in conservation ecology and - management strategies. The project will provide new expertise in Canary Island palaeoenvironmental reconstructions through training the ER in the latest palaeoenvironmental DNA analysis (PalEnDNA) at the Landcare Research Long-Term Ecology Lab, one - of the few labs in the world where this rapidly emerging field in palaeoecology is being applied to conservation on island settings. ISLANDPALECO will provide the ER with a new skill set in ancient molecular research that will be transferred to the - University of La Laguna where they currently do not exist. This will be the first time that PalEnDNA analysis will be implemented in the Canaries and probably one of the few cases on islands, becoming a valuable benchmark example of the applicability - of PalEnDNA analysis in other island regions. - - 2019-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Spain - - - ISLANDPALECO - - - H2020-MSCA-IF-2015 - - - 700952 - - - - - UNIVERSIDAD DE LA LAGUNA - UNIVERSIDAD DE LA LAGUNA - - - EUR 1 999 742 - - - Optoelectrical Dynamics of Ion channel Activation in Calcium Nanodomains - - - EUR 1 999 742 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In neurons, sites of Ca2+ influx and Ca2+ sensors are located within 20-50 nm, in subcellular “Ca2+ nanodomains”. Such tight coupling is crucial for the functional properties of synapses and neuronal excitability. Two key - players act together in nanodomains, coupling Ca2+ signal to membrane potential: the voltage-dependent Ca2+ channels (VDCC) and the large conductance Ca2+ and voltage-gated K+ channels (BK). BK channels are characterized by synergistic activation by - Ca2+ and membrane depolarization, but the complex molecular mechanism underlying channel function is not adequately understood. Information about the pore region, voltage sensing domain or isolated intracellular domains has been obtained separately - using electrophysiology, biochemistry and crystallography. Nevertheless, the specialized behavior of this channel must be studied in the whole protein complex at the membrane in order to determine the complete range of structures and movements - critical to its in vivo function. Using a combination of genetics, electrophysiology and spectroscopy, our group has measured for the first time the structural rearrangements accompanying whole BK channel activation at the membrane. From this unique - position, our first goal is to fully determine the real time structural dynamics underlying the molecular coupling of Ca2+, voltage and activation of BK channels in the membrane environment, its regulation by accessory subunits and channel effectors. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Spain - - - NANOPDICS - - - ERC-2014-CoG - - - 648936 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - AALBORG UNIVERSITET - FLOATING POWER PLANT A/S - - - EUR 845 838,36 - - - European Industrial DoCtorate on Offshore WiNd and Wave ENergy - - - EUR 845 838,36 - - - Ireland - Denmark - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - ICONN is a unique European Industrial Doctorate initiative to meet the current and future demand for highly skilled offshore wind and wave energy engineers by developing and advancing European capacity in the design, - development and performance optimisation for Offshore Wind and Wave Energy installations. The initiative is strongly shaped by active participation from industries, and will develop and enhance European capacity in the offshore renewable energy area - at a critical juncture in time when Europe strives to occupy a lead market position globally in this sector. - - 2019-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-EID - Marie Skłodowska-Curie Innovative Training Networks (ITN-EID) - - - MSCA-ITN-EID - European Industrial Doctorates - - - Ireland - - - ICONN - - - H2020-MSCA-ITN-2015 - - - 675659 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - - - EUR 248 063,40 - - - Segregated education in post-conflict Bosnia and the possibilities of future conflicts in Europe - - - EUR 248 063,40 - - - Ireland - - - Higher or Secondary Education Establishments - - The aim of this Fellowship is to provide Dr Maja Halilovic-Pastuovic with advanced interdisciplinary training and new skills and experience in order to enhance her innovative and creative potential, increase her knowledge - base, expand her career possibilities and enable her to reach professional maturity commensurate with a leading researcher in the EU. The remit of the Fellowship falls under the categories of transformation of societies, interethnic relations, and - education: systems and institutions. The researcher will be based for two years at the Josef Korbel School, University of Denver, working under the supervision of Professor Timothy Sisk. The return phase of the Fellowship will be completed in the - Irish School of Ecumenics at Trinity College Dublin under the supervision of Prof Etain Tannam. Research training will be implemented through an interdisciplinary project investigating segregated education in Bosnia and Herzegovina and security in - Europe. The specific aim of the project is to investigate if segregated education in post-conflict societies causes radicalisation of youth and increases the possibilities of future conflicts. The Researcher is a trained sociologist and the exposure - to the University of Denver whose expertise lies in the field of international relations and political science, and to Trinity College Dublin where expertise is focused on peace studies, will provide the researcher with interdisciplinary training - necessary for advancement of her career and the success of the project. The resources of the two host institutions will facilitate the development of an international academic network, as well as career mentoring, and will firmly establish the - researcher at the centre of the transnational interdisciplinary nexus addressing the challenge of European security. - - 2019-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Ireland - - - GATED - - - H2020-MSCA-IF-2015 - - - 708249 - - - - - UNIVERSITAT ZU LUBECK - UNIWERSYTET IM. ADAMA MICKIEWICZA W POZNANIU - DET KONGELIGE DANSKE KUNSTAKADEMIS SKOLER FOR ARKITEKTUR, DESIGN OG KONSERVERING. - CYBERTRONICA UG (HAFTUNGSBESCHRANKT) GMBH - IT-UNIVERSITETET I KOBENHAVN - UNIVERSITAET GRAZ - UNIVERSITAET PADERBORN - - - EUR 3 641 781 - - - Flora Robotica: Societies of Symbiotic Robot-Plant Bio-Hybrids as Social Architectural Artifacts - - - EUR 3 641 782,50 - - - Germany - Poland - Denmark - Germany - Denmark - Austria - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project's objective is to develop and to investigate closely linked symbiotic relationships between robots and natural plants and to explore the potentials of a plant-robot society able to produce architectural artifacts - and living spaces. We will create a society of robot-plant bio-hybrids functioning as an embodied, self-organizing, and distributed cognitive system. The system grows and develops over long periods of time in interactions with humans resulting in the - creation of meaningful architectural structures. The robotic assemblies (‘artificial plants’) support and control the biological plants through appropriate scaffolding, watering, and stimuli that exploit the plants’ different tropisms. The natural - plant, in turn, supports and controls the robotic plant by guiding it through growth and support the weight of the robot in later growth phases. The artificial plants are built from small heterogeneous sensing and actuation modules connected using - lightweight construction elements. Each robotic plant connects wirelessly to the Internet. In contrast to top-down control, we explore a developmental plasticity of bio-hybrid systems, where robots and plans grow together from sprout to adult stage - and form a closely co-dependent and self-organized system. The robot-plant organisms live in a human-inhabited environment and through interaction with humans grow into architectural structures (e.g., walls, roofs, benches) providing functionality - such as shade, air quality control, and stress relief. Humans, plants, and robots form an internet-connected social garden where desired structures and behavior patterns emerge based on both local interactions and global interaction with parts of the - garden growing at other locations. Hence, the social garden is a cultural system that shows long-term learning and adaptation where all past actions and interactions between the natural and artificial plants are represented in the embodiment of the - garden. - - 2019-03-31, ongoing project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.2."> - - - FETPROACT-2-2014 - Knowing, doing, being: cognition beyond problem solving - - - RIA - Research and Innovation action - - - Germany - - - flora robotica - - - H2020-FETPROACT-2014 - - - 640959 - - - - - GEORG-AUGUST-UNIVERSITAT GOTTINGENSTIFTUNG OFFENTLICHEN RECHTS - GEORG-AUGUST-UNIVERSITAT GOTTINGENSTIFTUNG OFFENTLICHEN RECHTS - KOBENHAVNS UNIVERSITET - - - EUR 1 901 427,84 - - - Weight metrology and its economic and social impact on Bronze Age Europe, West and South Asia - - - EUR 1 901 427,84 - - - Germany - Germany - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project explores the economical and societal transformations provoked by weights and measures during the Bronze Age in Western Eurasia. The impact and significance of weight-based measures for value assessments during the - Bronze Age is largely unknown und understudied. My objective is to unravel this empirical and intellectual gap in studies of the prehistoric and ancient economy. The project will uncover new sources for the reconstruction of trade and exchange - networks due to the identification of a mostly overlooked or ignored class of artefacts: early balance weights. This opens up a new understanding of the nature and extent of the earliest commercial economies in the world. The ambitious project aims - to document for the first time potential weights, often of unexpected simple shape, as well as canonical weights, frequently not sufficiently documented in a selection of cases studies between the Atlantic and the Indus. Further focus will be on - potential mass-related finished metal objects, standardization and pre-coinage currencies, contributing to the debate on the origins of money. Specific statistical methods and 3D scanning provide a novel tool package to verify assumptions in a - rigorous way. Hypotheses to be tested include identifying the potential correlation of the emergence of weight metrology to elucidating the first extensive trade in raw material (like silver, tin), the connection of weights to other administrative - and commercial tools like seals and script, and their impact of early conceptions of value. The early dissemination of weights and weighing systems will be analysed systematically on evidence from the Bronze Age in Western Eurasia. The proposed - research starts with identifying and documenting potential balance weights and mass related objects by archaeological indications and the rigorous application of various statistical methods, but progresses to developing and testing models of exchange - and transfer of innovations. - - 2020-07-31, ongoing project - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - WEIGHTANDVALUE - - - ERC-2014-CoG - - - 648055 - - - - - TECHNISCHE UNIVERSITEIT DELFT - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - STICHTING WAAG SOCIETY - ARTSHARE INVESTIGACAO TECNOLOGIA EARTE LDA - FONDAZIONE SANTA LUCIA - T.S.R.ACT SRO - - - EUR 549 727 - - - BrainHack: Bringing the arts and sciences of brain and neural computer interface together - - - EUR 549 727 - - - Netherlands - Ireland - Netherlands - Portugal - Italy - Czech Republic - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - We witness a rapid development of Brain/Neural Computer Interaction (BNCI) research including hyperscanning and collaborative BNCIs. Several recent BNCI community driven CSAs have addressed this topic (Future BNCI, BNCI - Horizon 2020 ) with the BCI Society being in progress of establishing. At the same time, a growing community of international artists is exploring the boundaries of brain physiology based interaction in cinema, theatre and interactive installations. - Artists address questions of BNCI ethics and aesthetics which are often overlooked by scientists but which spur general public discussion. - - - 2017-12-31, closed project | - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-3-2015 - Coordination and Support Activities - - - CSA - Coordination and support action - - - Netherlands - - - BrainHack - - - H2020-FETOPEN-2015-CSA - - - 686987 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - - - EUR 1 999 700 - - - 3D Printing of Cell Laden Biomimetic Materials and Biomolecules for Joint Regeneration - - - EUR 1 999 700 - - - Ireland - Ireland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Osteoarthritis (OA) is a serious disease of the joints affecting nearly 10% of the population worldwide. Realising an efficacious therapeutic solution for treating OA remains one of the greatest challenges in the field of - orthopaedic medicine. This proposal envisions a future where 3D bioprinting systems located in hospitals will provide ‘off-the-shelf’, patient-specific biological implants to treat diseases such as OA. To realise this vision, this project will use 3D - bioprinting to generate anatomically accurate, biomimetic constructs that can be used to regenerate both the cartilage and bone in a diseased joint. The first aim of this proposal is to print a mesenchymal stem cell laden biomaterial that is both - immediately load bearing and can facilitate the regeneration of articular cartilage in vivo, such that the bioprinted construct will not require in vitro maturation prior to implantation. Mechanical function will be realised by integrating an - interpenetrating network hydrogel into a 3D printed polymeric scaffold, while chondro-inductivity will be enhanced by the spatially-defined incorporation of cartilage extracellular matrix components and chondrogenic growth factors into the bioprinted - construct. The second aim of the proposal is to use 3D bioprinting to create a cell-free, composite construct to facilitate regeneration of the bony region of a large osteochondral defect, where vascularization will be accelerated by immobilizing - spatial gradients of vascular endothelial growth factor into the implant. The third aim of the proposal is to scale-up the proposed 3D bioprinted construct to enable whole joint regeneration. Finite element modelling will be used determine the - optimal structural characteristics of the scaled-up implant for it to fulfil its required mechanical function. If successful, such an implant would form the basis of a truly transformative therapy for treating degenerative joint disease. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Ireland - - - JointPrinting - - - ERC-2014-CoG - - - 647004 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - - - EUR 175 866 - - - High-Resolution X-ray Structures of Full-Length Cystic Fibrosis Transmembrane Conductance Regulator - - - EUR 175 866 - - - Ireland - - - Higher or Secondary Education Establishments - - This proposal seeks to solve the high-resolution X-ray crystal structure of full-length Cystic Fibrosis Transmembrane Conductance Regulator (CFTR), an anion channel which regulates chloride ion concentration at the - lumen-exposed surface of epithelial cells. Mutations of the CFTR gene cause cystic fibrosis (CF), a lethal disease which results in bowel obstruction, lung disease and premature death. CFTR is an ATPase and a member of the ATP-Binding Cassette (ABC) - transporter family of proteins which has an allosteric Regulatory (R) domain not found in other ABC transporters. From the structure of CFTR, its mode of action will be revealed, focusing on the two sites of ATP hydrolysis and key residues for - channel gating. CFTR will be crystallized alone and in the presence of the pharmacological agent Kalydeco, a small molecule from Vertex Pharmaceuticals that is used for the treatment of CF and reduces CF symptoms. The initial high-resolution X-ray - crystal structure is a foundation from which personalized drug design work can begin. Therefore, the Kalydeco-CFTR complex structure will be used for ligand optimization of Kalydeco, an iterative process which will improve Kalydeco’s specificity and - pharmacokinetics. The latest technology, including in meso in situ serial crystallography and X-ray free electron lasers for serial femtosecond crystallography will be used as well as traditional synchrotron X-ray sources. These Actions use an - interdisciplinary mix of crystallography, chemistry, biochemistry, biophysics and computational structural determination programs. The work will take place in Ireland in the lab of Dr. Martin Caffrey at Trinity College Dublin, a distinguished - researcher in the field of membrane structural and functional biology. The prestigious Marie Skłodowska-Curie fellowship will enable the candidate to actualize many objectives outlined in her career development plan in order to become an independent - researcher. - - 2018-11-15, ongoing project - - - 2016-11-16 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Ireland - - - CF_struct - - - H2020-MSCA-IF-2015 - - - 704848 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - - - EUR 1 979 366 - - - Towards Artificial Enzymes: Bio-inspired Oxidations in Photoactive Metal-Organic Frameworks - - - EUR 1 979 366 - - - Ireland - Ireland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Metal-organic frameworks (MOFs) are key compounds related to energy storage and conversion, as their unprecedented surface areas make them promising materials for gas storage and catalysis purposes. We believe that their - modular construction principles allow the replication of key features of natural enzymes thus demonstrating how cavity size, shape, charge and functional group availability influence the performances in catalytic reactions. This proposal addresses - the question of how such novel, bio-inspired metallo-supramolecular systems can be prepared and exploited for sustainable energy applications. A scientific breakthrough that demonstrates the efficient conversion of light into chemical energy would be - one of the greatest scientific achievements with unprecedented impact to future generations. We focus on the following key aspects: - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Ireland - - - Supramol - - - ERC-2014-CoG - - - 647719 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - - - EUR 149 774 - - - Ink-Jet printed supercapacitors based on 2D nanomaterials. - - - EUR 149 774 - - - Ireland - Ireland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This proposal will determine the technical-economic viability of scaling-up ultra-thin, ink-jet printed films based on liquid-phase exfoliated single atomic layers of a range of nanomaterials. The PI has developed methods to - produce in liquid nanosheets of a range of layered materials such as graphene, transition metal oxides, etc. These 2D-materials have immediate and far-reaching potential in several high-impact technological applications such as microelectronics, - composites and energy harvesting and storage. 2DNanoCaps (ERC ref: 278516) has demonstrated that lab-scale ultra-thin graphene-based supercapacitor electrodes result in unusually high-power and extremely long device life-time (100% capacitance - retention for 5000 charge-discharge cycles at the high power scan rate of 10,000 mV/s). This performance is an order of magnitude better than similar systems produced with conventional methods which cause materials restacking and aggregation. A - following ERC PoC grant (2D-USD, Project-Number 620189) is currently focussed on up-scaling the production of thin-films deposition methods based on ultrasonic spray for the production of large-area electrodes for supercapacitors applications. In - this proposal we want to explore the new concept of manufacturing conductive, robust, thin, easily assembled electrode and solid electrolytes to realize highly-flexible and all-solid-state supercapacitors by ink-jet printing. This opportunity is - particularly relevant to the electronics and portable-device industry and offers the possibility to solve flammability issues, maintaining light weight, flexibility, transparency and portability. In order to do so it will be imperative to develop - ink-jet printing methods and techniques. We believe our combination of unique materials and cost-effective, robust and production-scalable process of ultra- thin ink-jet printing will enable us to compete for significant global market opportunities - in the energy-storage space. - - 2016-09-30, closed project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2014 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Ireland - - - 2D-Ink - - - ERC-2014-PoC - - - 665674 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - - - EUR 266 063,40 - - - 'Science as Applied to Building' : Science, Construction, and Architectural Acoustics (1914-1954) - - - EUR 266 063,40 - - - Ireland - - - Higher or Secondary Education Establishments - - The aim of this Fellowship is for the researcher, Dr Fiona Smyth, to develop the professional prowess, advanced training, interdisciplinary skills, high-impact dissemination, and practical experience commensurate with a - leading independent researcher in the EU. The remit of the Fellowship research falls under the categories of history of science, history of construction and architectural acoustics. The researcher will be based for two years in the Dept. of the - History of Science in Harvard University, working under the supervision of Professor Peter Galison. The third year of the Fellowship will be completed in the Acoustics Research Group in the School of Engineering, Trinity College Dublin (TCD) working - under the supervision of Professor Henry Rice. Research training will be implemented through an interdisciplinary project investigating the 20th century emergence of architectural acoustics as a branch of modern building science in Britain and - Ireland. On the outgoing phase of the Fellowship the researcher will access expertise, advanced training and mentoring in the History of Science. No Irish university has yet established a dedicated History of Science department. In the return phase - the researcher will consolidate the knowledge and experience gained in the US through advanced laboratory training in acoustics. In TCD she will be given the opportunity to embed her new knowledge in the design of interdisciplinary curricula for - graduate students. Under the guidance of international experts, she will acquire an invaluable skill-set bridging humanities, science and technology with implications for contemporary societal and economic application. The resources of the host - departments will facilitate development of an interdisciplinary and international academic network as well as career mentoring. The Fellowship will establish the researcher firmly at the centre of interdisciplinary research in the histories of - building science and architectural acoustics. - - 2018-06-30, ongoing project | - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Ireland - - - SAAB - - - H2020-MSCA-IF-2014 - - - 654796 - - - - - UNIVERSIDAD REY JUAN CARLOS - - - EUR 170 121,60 - - - PhotoCloth: A framework to synthesize real-time photorealistic cloth animation from video input. - - - EUR 170 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - Computer Graphics is the area of computer science that studies methods for digitally synthesizing and animating visual content. Among all the potential contexts where computer graphics techniques can be used, cloth animation - is a particularly interesting case since, in the real world, clothing is far more than just the physical objects that we wear; clothing is a key element to show someone’s expressiveness and motion, it even defines his or her identity. - - - 2018-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - PhotoCloth - - - H2020-MSCA-IF-2015 - - - 707326 - - - - - UNIVERSIDAD REY JUAN CARLOS - - - EUR 201 726 - - - Vulnerability of soil organic carbon to climate change in permafrost and dryland ecosystems - - - EUR 201 726 - - - Spain - - - Higher or Secondary Education Establishments - - Soil organic matter provides essential ecosystem services and is one of the largest C reservoirs on Earth, holding more than three-fold as much C as does the atmosphere. Over 75% of the global soil organic C pool is stored in - permafrost and dryland regions, both under high pressure due to climate change. In particular, global warming may accelerate soil organic matter decomposition in these ecosystems, which may dramatically endanger their functioning and worsen climate - change by releasing significant amounts of CO2 to the atmosphere. However, the rate of this effect and to what extent it may be offset by warming-induced increases of plant-derived organic inputs remain highly uncertain. The main objective of this - project is to gain a deeper insight into the vulnerability of soil organic matter to climate change in permafrost and drylands, and to explore potential implications in terms of ecosystem functioning and feedback to global warming. We will use - globally unique ecosystem warming experiments in Alaska (permafrost) and central Spain (dryland), with a well-established monitoring of plant productivity, phenology, and nutrient status, soil physical, chemical, biochemical, and microbiological - properties, and CO2 fluxes. We will focus on the destabilization, stabilization, and transformation processes of soil organic matter at the molecular level by using an unparalleled combination of state-of-the-art methods for soil organic matter - fractionation into pools directly related to conceptual preservation mechanisms, powerful stable and radioactive isotope techniques, and advanced nuclear magnetic resonance tools. VULCAN will fill major gaps in our knowledge, will make this - information widely available to scientists, policy makers, and the general public, and will provide the Fellow with the necessary knowledge, skills, networking, and experience to lead future research projects related to the feedbacks between climate - change and terrestrial ecosystems in Europe. - - 2018-06-30, ongoing project | - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Spain - - - VULCAN - - - H2020-MSCA-IF-2014 - - - 654132 - - - - - UNIVERSIDADE DA CORUNA - HELSINGIN YLIOPISTO - INESC ID - INSTITUTO DE ENGENHARIADE SISTEMAS E COMPUTADORES, INVESTIGACAO E DESENVOLVIMENTO EM LISBOA - ENXENIO SL - - - EUR 648 000 - - - Bioinformatics and Information Retrieval Data Structures Analysis and Design - - - EUR 648 000 - - - Spain - Finland - Portugal - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Nowadays computers are used to process huge amounts of information, for example a major search engine processes tens of thousands of searches per second. Still the future of the information age is at risk. Computer - architectures will not be resilient enough for the next information challenges. It is not only a matter of word size or clock cycles. New DNA sequencing technologies are evolving much faster than Moore's law, this means that they are evolving faster - than the amount of transistors that go into CPUs and GPUs. Moreover computer disks are, by far, the slowest part of the architecture and are evolving even slower, therefore widening the relative time that information takes to reach the processor. - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Spain - - - BIRDS - - - H2020-MSCA-RISE-2015 - - - 690941 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - - - EUR 175 866 - - - MULTImodal and MULTIparty Social Interactions MOdelling - - - EUR 175 866 - - - Ireland - - - Higher or Secondary Education Establishments - - The project addresses the modelling of multimodal communicative human behaviour during natural interactions in multiparty settings and specifically the conversational and feedback strategies of the interaction participants in - terms of attention, engagement and conflict management. The knowledge base for this modelling problem will be a collection of human-human interaction recordings to be acquired through a concise experimental protocol and state-of-the-art equipment. - The communicative behavior will be analysed in multimodal signals, including facial expressions, gaze and prosodic cues that provide information about social interaction management and speakers’ attitudes. This information becomes more complex in - group interactions, where a management mechanism will be discovered and modelled. These low-level signals will be examined in relation to their timing and sequence to infer and model high-level signals of attention, engagement and conflict, and - subsequently implement modules to feed existing HCI interfaces such as dialogue systems or avatars. The implementation of such novel models will allow for the creation of more sophisticated human-like agent-based interfaces of high quality - communication experience, especially in scenarios where social and cognitive skills, in addition to the communicative ones, are crucial for the success of the interaction, i.e. in the education, customer care domains and web applications requiring - interfaces triggered by human communication. The project builds on the strengths of the applicant in multimodal communication and language technology, and combines these with new training in intelligent systems and human-computer interaction to - support a new research direction and to strengthen cross-European collaboration. The host provides an excellent supportive environment conducive to the interdisciplinary research envisaged in the project and the training objectives of the fellowship - in view of the applicant’s career development. - - 2018-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Ireland - - - MULTISIMO - - - H2020-MSCA-IF-2015 - - - 701621 - - - - - UNIVERSIDAD REY JUAN CARLOS - UNIVERSIDAD REY JUAN CARLOS - - - EUR 149 545 - - - Computer-Aided Fashion with Yarn-Level Fabric Models - - - EUR 149 545 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The Animetrics ERC Starting Grant has led to the invention of the first computer models capable of simulating in an accurate, efficient and robust manner the behavior of full textiles using a yarn-level representation. The - proposed models handle frictional yarn interactions at the small scale, yet they naturally produce the rich large-scale nonlinearity of textiles. In contrast, models used in the fashion, engineering, or VFX industries nowadays, describe textiles as a - continuum, and do not reach the accuracy required for validating the mechanical behavior and visual appearance of cloth. - - 2018-06-30, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2015 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Spain - - - FabricMetrics - - - ERC-2015-PoC - - - 713742 - - - - - UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA - AZ.OSP.-UNIV.S.M.MISERICORDIA DI UDINE - UNIVERSITY OF LINCOLN - - - EUR 441 000 - - - Nanostructured molecular decoders for the quantitative, multiplexed, layer-by-layer detection of disease-associated proteins - - - EUR 441 000 - - - Italy - Italy - United Kingdom - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - - The long-range goal of this project is to develop a molecular nanodevice, based on nucleic acid-protein conjugates, for the multiplexed, quantitative imaging of biomarkers in tissue samples and cultured cells. - - 2019-03-31, ongoing project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Italy - - - Immuno-NanoDecoder - - - H2020-MSCA-RISE-2014 - - - 645684 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - - - EUR 175 162,50 - - - Discover Research Dublin - European Researchers' Night 2014/2015 - - - EUR 175 162,50 - - - Ireland - - - Higher or Secondary Education Establishments - - Ireland’s leading university, Trinity College Dublin (TCD), in partnership with the Royal College of Surgeons in Ireland (RCSI), is seeking funding to plan, promote and host Discover Research Night as part of European - Researchers’ Night in 2014 and 2015. On Discover Research Night 26 September 2014 and 25 September 2015, TCD and RCSI will offer the general public a wide range of interactive and hands-on activities, providing direct contact with researchers and - allowing for discovery, questions and participation. The objectives of the project are to challenge perceptions held by the general public about researchers, to promote research as an exciting career option, to demonstrate creativity and innovation - in research across all disciplines and to show that researchers are dynamic contributors to society. Interaction with researchers during EU Researchers’ Night will challenge stereotypes which have created barriers between the general public and - researchers. Specific career-focused events will identify and promote arrays of opportunities for research careers. Diverse activities which will help to show the public how research benefits the community. Events will showcase exciting innovative - research from several academic strands at TCD and RCSI, will invite the public to interact with the vibrant research communities from both participating institutes, aiming to delight and stimulate the imagination of all participants from school - children and their families, to visitors to Dublin and the local community. Activities hosted on the night will be grouped under four broad themes – Body Parts including ‘Discover the Brain!’, ‘Mending Broken Hearts, ‘Attack of the Heart’; Language, - Thought & Knowledge Transfer including ‘Identities in Transformation’, ‘Living Thought/Thinking Life’, ‘Tower of Babel’, Creativity in Research featuring ‘Biodiversity in our Lives’ and Meet the Researchers including ‘Thesis-in-3’, ‘Innovation - Café’, ‘Women in Science’ and ‘Career Clinic’. - - 2015-11-30, closed project - - - 2014-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.5."> - - - MSCA-NIGHT-2014 - European Researchers' Night (NIGHT) - - - CSA - Coordination and support action - - - Ireland - - - DiscoverResearch - - - H2020-MSCA-NIGHT-2014 - - - 633292 - - - - - UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN - THE UNIVERSITY OF NOTTINGHAM - UNIVERSITAT POLITECNICA DE CATALUNYA - LLOYD'S REGISTER EMEA IPS - EQUIPOS NUCLEARES SA SME - FULL SCALE DYNAMICS LIMITED - PHI-MECA ENGINEERING - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - OVE ARUP & PARTNERS IRELAND - - - EUR 3 701 306,88 - - - Training in Reducing Uncertainty in Structural Safety - - - EUR 3 701 306,88 - - - Ireland - United Kingdom - Spain - United Kingdom - Spain - United Kingdom - France - Ireland - Ireland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The growth of cities, impacts of climate change and the massive cost of providing new infrastructure provide the impetus for this proposal – entitled Training in Reducing Uncertainty in Structural Safety (TRUSS) – which will - maximize the potential of infrastructure that already exists. If flaws in a structure can be identified early, the cost of repair will be vastly reduced, and here an effective monitoring system would allow identifying the optimum time to repair as - well as improving structural safety. But safety is difficult to quantify and requires a deep understanding of the uncertainty associated to measurements and models for the structure and the loads. TRUSS will gather this understanding by bringing - together an intersectoral and multidisciplinary collaboration between 4 Universities, 11 Industry participants and 1 research institute from 6 European countries. The consortium will combine and share expertise to offer training at an advanced level - as new concepts for monitoring, modelling and reliability analysis of structures are emerging all the time. TRUSS will make knowledge of structural safety grow by incorporating these emerging technologies (hi-tech monitoring and manufacturing, - computing, etc.) into the training programme and it will support job creation by enabling a wider talent pool of skilled and accredited engineering graduates with business, entrepreneurship, communication, project management and other transferrable - skills. The training programme will be structured into taught modules combined with original research supported by secondments that will expose 14 fellows to both academia and industry. While developing tools that will reduce uncertainty in - structural safety and improve infrastructure management, TRUSS will lay the basis for an advanced doctoral programme that will qualify graduates for dealing with the challenges of an aging European infrastructure stock, thereby enhancing their career - prospects in both industry and academia. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Ireland - - - TRUSS - - - H2020-MSCA-ITN-2014 - - - 642453 - - - - - UNIVERSIDAD DE BURGOS - UNIVERSITA DEGLI STUDI DEL PIEMONTE ORIENTALE AMEDEO AVOGADRO - THE UNIVERSITY OF BIRMINGHAM - BIONANONET FORSCHUNGSGESELLSCHAFT MBH - Research and Development of Carbon Nanotubes S.A. - SITEX 45 SRL - NOVAMECHANICS LIMITED - NANOTECHNOLOGY INDUSTRIES ASSOCIATION - - - EUR 706 500 - - - Developing and implementation of a new generation of nanosafety assessment tools - - - EUR 706 500 - - - Spain - Italy - United Kingdom - Austria - Greece - Romania - Cyprus - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - - NanoMaterials safety is of great societal concern and raises many questions for the general public, governments, industry, scientists and regulators. Identifying and controlling the hazards associated with NMs is required to - ensure the safety in parallel to exploiting the technological benefits. - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Spain - - - NANOGENTOOLS - - - H2020-MSCA-RISE-2015 - - - 691095 - - - - - AGENCE NATIONALE DE SECURITE SANITAIRE DE L'ALIMENTATION, DE L'ENVIRONNEMENT ET DU TRAVAIL - - - EUR 185 076 - - - Multi-approach determination of metal based pesticides in food - - - EUR 185 076 - - - France - - - Research Organisations - - The industrial and agricultural activities of the modern society lead to significant release of a large number of toxic substances into the environment having an ultimate impact on the food quality and human health. Many of - such chemicals are used in agriculture as pesticides, fungicides, etc. to enhance the productivity. This is the case of dithiocarbamates (DTC) that are one of the relatively large used fungicides being effective against a broad spectrum of fungi and - plant diseases. Despite the significant environmental and food chain impact of DTC, the current analytical approaches for their determination suffer from serious drawbacks. The European reference method for this purpose relies on non-selective - quantification by indirect determination of the sum of DTC species hence this approach provides incomplete information on the exposure to individual DTC. The present proposal aims at the development and validation of a method for accurate and - selective determination of DTCs in food by a multi-approach strategy. A combination of analytical methodologies such as those currently employed for trace metals speciation and also for organic contaminants will be developed and fully validated. - These methodologies will be critically compared through the analysis of real-life food samples from EU and imported from external markets. The impact of different cooking modes on DTC degradation pathways will also be investigated. By combining - powerful separation techniques such as high performance liquid chromatography with elemental and molecular spectrometry, this project will allow obtaining a deeper knowledge on the presence of individual DTCs in various foodstuff and of their - degradation mechanisms during food processing. Additionally, it will consistently contribute to the development of a reference method for selective DTC determination in food hence having a great impact on the scientific research in food quality - control at European level. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - MET-PEST - - - H2020-MSCA-IF-2016 - - - 753053 - - - - - ASTON UNIVERSITY - - - EUR 183 454,80 - - - Improving the economic feasibility of the biorefinery through catalysis engineering: enhancing the catalyst performance and optimizing valuable product yields - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Catalytic pyrolysis of biomass is a process for the conversion of lignocellulosic biomass to a liquid product that has potential to be utilized as a fuel, a source of renewable chemicals and as an alternative to crude oil for - upgrading to transportation fuels. ZSM-5 zeolite is the most studied catalyst for this process due to its acidity and shape-selectivity, which favour the conversion of biomass oxygenates to valuable aromatic hydrocarbons and limit the formation of - coke. Among the shortcomings of the ZSM-5 zeolite is the small size of its pores; these small pores do not allow the large molecules in the pyrolysis vapours to access the active acid sites. Secondly, its sensitivity to biomass metals leads to - poisoning and deterioration of its selectivity. Coupled with the high cost of the ZSM-5, the later leads to significant operating costs that arise from the necessity to replace the deactivated catalyst with fresh material at high rates. - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ECOCAT - - - H2020-MSCA-IF-2016 - - - 752941 - - - - - ALBERT-LUDWIGS-UNIVERSITAET FREIBURG - - - EUR 2 371 800 - - - FRIAS COFUND Fellowship Programme for Junior and Senior Researchers - Phase 2 - - - EUR 4 743 600 - - - Germany - - - Higher or Secondary Education Establishments - - The Freiburg Institute for Advanced Studies (FRIAS) is an internationally renowned university-based institute for advanced studies that offers time-limited fellowship stays for excellent junior and senior researchers from - around the world. The Institute is part of the University of Freiburg, one of the leading research universities in Europe. - - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2016 - Co-funding of regional, national and international programmes - - - MSCA-COFUND-FP - Fellowship programmes - - - Germany - - - FCFP - - - H2020-MSCA-COFUND-2016 - - - 754340 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 99 775 - - - Wavelength tunable Advanced Single Photon Sources Non-laboratory Environment Specification and Testing - - - EUR 99 775 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Triggered single photon sources are key enabling tools in the new technology of quantum communications and a host of quantum optics research, but have not found widespread use because robust and portable devices have yet to be - commercialised. The FP7 WASPS project is completing laboratory-based demonstrator experiments for a new range of plug-in single photon sources that can ultimately be operated at ambient temperatures and in non-laboratory environments. The devices, - based on nitrogen-vacancy colour centres in diamond coupled to optical microcavities, offer a degree of wavelength tunability and a flexible design in which the active component can be replaced and upgraded. Work towards construction of a - field-testable prototype device has started. In this Innovation Launchpad project, we propose to carry out critical steps in the development and field testing of this prototype that will provide key performance information to companies looking to - manufacture and market the technology. These will involve innovative refinement of the active module containing the cavity and single photon emitter, development of module assembly protocols compatible with manufacturing, and testing of the prototype - in a free-space quantum key distribution system. The project will bring robust triggered single photon sources closer to market and will promote innovation and entrepreneurship within the H2020 FET programme. - - 2018-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-04-2016-2017 - FET Innovation Launchpad - - - CSA - Coordination and support action - - - United Kingdom - - - WASPSNEST - - - H2020-FETOPEN-4-2016-2017 - - - 754509 - - - - - THE QUEEN'S UNIVERSITY OF BELFAST - - - EUR 1 569 600 - - - Supporting Pioneer doctoral Researchers through 3i Knowledge partnerships - - - EUR 3 139 200 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The SPaRK Programme is driven by the need to develop future leaders whose skills combine disciplinary excellence with a capacity for interdisciplinary and intersectoral working that creates genuinely disruptive thinkers. SPaRK - recognises that genuinely game-changing intersectoral, international and interdisciplinary collaboration does not happen simply by making available opportunities for mobility, placements, or input from other disciplines. It is therefore designed to - offer an innovative model of professional and scientific development that is proactively training researchers to be able to maximise the potential of these 3i partnerships. Only by rethinking our current, competence-based skills agenda in ways that - embrace a model based on intellectual flexibility and creativity can we prepare the leaders who will be equipped to respond to constantly shifting global challenges. The SPaRK programme thus proposes the integration of disciplinary excellence with a - meaningful reflection on the possibilities both of interdisciplinarity and of mobility across cultural, linguistic, professional and epistemological borders. - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2016 - Co-funding of regional, national and international programmes - - - MSCA-COFUND-DP - Doctoral programmes - - - United Kingdom - - - SPARK - - - H2020-MSCA-COFUND-2016 - - - 754507 - - - - - FUNDACAO D. ANNA SOMMER CHAMPALIMAUD E DR. CARLOS MONTEZ CHAMPALIMAUD - - - EUR 148 635,60 - - - Functional role of neuronal spontaneous activity for sensory processing - - - EUR 148 635,60 - - - Portugal - - - Research Organisations - - Understanding how the brain processes sensory stimuli to guide behavior is still an unresolved mystery in neuroscience. The view that behavior may be passively guided by the senses is challenged by the observation that the - brain is always spontaneous active. Even cortical areas that are supposed to represent features of the sensory environment manifest spontaneous activity (SA) in the absence of external inputs. The similarity between SA and sensory-evoked activity - (EA) has been interpreted as learning of features of the external world by cortical circuits. However, the mechanism by which SA affects brain computation is largely unknown. In this proposal we aim at elucidating the functional role of SA for - processing of sensory information in the auditory modality. We will take advantage of state-of-the-art tools available in mice to modulate and record the activity of large populations of neurons across cortical layers. Mice will be trained to perform - frequency (or location) discrimination tasks and expectation will be generated by using trials in blocks in which the sound location (or frequency) probability will vary. We hypothesize that the induced expectation will facilitate sensory - discrimination and manifest as specific patterns of SA before stimulus presentation. We will then manipulate optogenetically auditory cortex to causally test the role of SA in the task. Finally, we will record the simultaneous activity of a large - number of neurons to understand mechanistically how SA may affects the processing of incoming sensory stimuli. Our study has the potential to uncover new neuronal mechanisms underlying sensory processing. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Portugal - - - Spontaneous activity - - - H2020-MSCA-IF-2016 - - - 753819 - - - - - MAGYAR TUDOMANYOS AKADEMIA AGRARTUDOMANYI KUTATOKOZPONT - - - EUR 146 239,20 - - - Exploiting the legacy of Central European wheat landraces for improving the ecological adaptation ability of wheat - - - EUR 146 239,20 - - - Hungary - - - Research Organisations - - Wheat the most important food crop in Europe with an increasing demand to preserve its production potential to ensure long-term food security. However, wheat is facing such challenges as climate change and the severe genetic - bottleneck of cultivated wheat imposed by domestication, cannot surmount such difficulties. Wheat landraces are better adapted than modern cultivars to changing climate conditions and to stress environments. The conservation and effective management - of crop diversity are thus essential to prepare future plant cultivars to the effects of climate change. A significant loss of named landrace varieties in both Europe and worldwide already caused a massive loss of crop genetic diversity and charged a - substantial risk for future food security. The transfer of genetic diversity of European landraces into modern wheat cultivars can give valuable responses for climate change effects. The present study aims to introduce a high throughput state of the - art genotyping system into the Hungarian breeding research to analyse the genetic diversity of the Central European landrace collection. The 15K wheat genotyping array uses 12.905 gene-based, predominantly haplotype-specific Single Nucleotide - Polymorphism (SNP) markers providing a maximum of information accompanied by low analysis costs. We will use this genotyping system to identify favourable, new alleles of stress tolerance and quality in the Central European landraces. Comparisons to - modern elite bread wheat cultivars will be presented and genome-wide association study will be carried out between SNPs and agronomically important traits. Phenotypic characterizations will be performed on 200 landraces and 70 modern wheat cultivars - targeting ecological adaptation, biotic and abiotic stress tolerance and end-use quality. During this project we will identify new QTLs and genes, useful to improve limiting factors of grain yield, such as drought tolerance, plant phenology and - resistance to diseases. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Hungary - - - LANDRACES - - - H2020-MSCA-IF-2016 - - - 752453 - - - - - UNIVERSITY OF EAST LONDON - - - EUR 195 454,80 - - - (Re)Conceptualizing teacher educator professionalism - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The need for a competent teaching force as a warrant for high quality education remains a central concern in many countries. Paradoxically, research focusing directly on the professional knowledge of teacher educators remains - scarce. The implicit assumption is that a teacher educator simply teaches (his/her subject) in higher education and that teaching novice teachers does not require any additional preparation or expertise. As a result, a research-based understanding of - teacher educators' professionalism is missing. This project addresses this knowledge gap and focuses on how teacher educators make sense of their work and enact their expertise. More specifically, we will study the content of teacher educators’ - professionalism by looking at how it actually operates in practice. Drawing on positioning theory, we frame teacher education practices as discursive practices in which teacher educators position both themselves and their student teachers in - particular ways. These positionings strongly impact student teachers' (possibilities for) learning. Data collection includes videotaping of teacher education practices, biographical interviews (with teacher educators), questionnaires (with student - teachers), and document analysis. This project will result in a systematic conceptualization of teacher educators' professionalism which is new to the field and offers a strong basis for future research. Results will also have direct knowledge - utilization purposes for teacher educators themselves by opening powerful perspectives for them to understand possible threats to the effectiveness of their practice and actively work towards its improvement. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ReconTEP - - - H2020-MSCA-IF-2016 - - - 751294 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 158 121,60 - - - MRI Signal To Recover Unique Cerebral TissUe Response to changEs - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - MRI-STRUCTURE is an innovative non-invasive imaging framework that will provide access to unexplored microstructural information in brain, targeting the scarcity of microstructural models able to extract meaningful biomarkers - from the diffusion MRI signal in grey matter (GM). It is based on a synergy between different approaches: simulations, modeling, acquisition and analysis of real data, implementation of rodent model of brain insults, translation to human. The final - aim of the project is to increase our knowledge of brain structure in health and disease, with a special focus on the themes of neuroinflammation, demyelination and axon degeneration. These physiological processes are interplaying phenomena involved - in the brain’s reaction to different stimuli, which have recently become a hot topic in brain research, due to their involvement in the pathogenesis of several neurodegenerative and psychiatric disorders. The specific objectives of MRI-STRUCTURE are: - 1) to develop a new biophysical model of diffusion MRI in GM, capturing salient aspects of its microstructure; 2) to validate the model by triggering selective activation of different compartments in selected brain areas using established models of - inflammation, demyelination and degeneration in rats; 3) to translate this approach to human brain in vivo in a cohort of healthy volunteers (during a secondment in CUBRIC, one of the European hubs for neuroimaging); and 4) to disseminate the - framework to a wide clinical audience through a secondment in the startup Mint Labs, and explore its commercial applicability. An instrument with capacity to characterize relevant aspects of tissue microstructure in vivo and noninvasively is expected - to have a tremendous impact on our knowledge of the pathophysiology of many brain pathologies, ultimately leading to early diagnosis, better (e.g., personalised) monitoring of the disease course and of the efficacy of new therapies. - - 2019-01-15, ongoing project - - - 2017-01-16 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - MRI-STRUCTURE - - - H2020-MSCA-IF-2016 - - - 749506 - - - - - INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM - - - EUR 172 800 - - - Bottom-up PV module energy yield and integrated reliability model for site-specific design optimization - - - EUR 172 800 - - - Belgium - - - Research Organisations - - Photovoltaic (PV) module reliability is a critical factor for energy yield predictability, and reduced PV cost of electricity. Today, there is limited understanding of PV reliability issues under real-field conditions; and - none of the state-of-the-art energy yield models can predict their long-term performance considering lifecycle degradation and failure propagation. Ultimate objective of the planned research is to develop the first bottom-up reliability model for - selected PV failure/degradation modes, coupled with advanced simulation of real-field stress factors. Broader vision of the Project is to yield a novel design-for-reliability (DfR) protocol for site-specific optimization of PV module concepts. - Following a “closed-loop learning” approach, the Project will be implemented in three workpackages (WP). In WP1, analysis of field diagnostic and meteorological data will be performed for selected PV installations and climatic zones, aiming to - correlate degradation rates and/or failure occurrences, with site-specific stress factors. WP2 will involve the fabrication of PV samples; which, will undergo novel reliability tests based on insights from WP1, and enable the development of a novel - physics/chemical PV reliability models that can be adapted to specific sites and module designs. Then, advanced simulations of PV lifecycle degradation, based on the reliability models coupled to bottom-up energy yield modelling will be developed in - WP3. Final results of the project will be a predictive reliability tool and site-specific PV design and qualification guidelines. The project brings together the know-how of the Host, in advanced energy yield modelling and PV module technology - innovation and characterization, and the applicant’s experience in PV field diagnostics and reliability; thus, giving a multidisciplinary training by research to the applicant in industrial research environment at an independent research center. - - 2020-02-18, Grant Agreement signed - - - 2018-02-19 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Belgium - - - PVMINDS - - - H2020-MSCA-IF-2016 - - - 752117 - - - - - FUNDACIO CENTRE DE REGULACIO GENOMICA - - - EUR 158 121,60 - - - Mechanisms of selective transmission of epigenetic marks through the male germ line - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - During spermatogenesis, germ cells go through important chromatin remodelling steps, the most striking being the replacement of histones by protamines, which promotes the compaction of the paternal genome in the sperm . - However, a proportion of nucleosomes, ~1% in mice and ~15% in humans, are retained following protamine incorporation. It is thought that those remaining histones might play a role in the development process after fertilization possibly by - transmitting epigenetic information to the progeny. - - 2019-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - EpiRetention - - - H2020-MSCA-IF-2016 - - - 751651 - - - - - THE UNIVERSITY OF BIRMINGHAM - - - EUR 195 454,80 - - - Short Videos to Increase Learners uptake on Online Content - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Introduction: Students use the Internet as the first point of contact when searching for learning materials to assist their studies. Such content may have a low evidence based background and may be misleading. One learning - medium that is rated highly by students is the use of short educational videos. Objectives: The aim of this project is to create short video learning materials which are peer reviewed and accessible for dental students. Their creation and use will be - an exemplar that may be used in dentistry and have a framework that allows translation into other disciplines. Material and Methods: A questionnaire will be distributed to European Dental Courses to verify their use of Information and Communication - Technologies (ICT) with a focus on the use of short online videos. Following this short instructional videos will be created in several dental subjects and made available online following peer review. Their content will be evaluated qualitatively - using face to face interviews with both students and their teachers. Following dissemination at dental education conferences, selected European partners will be invited to take part in evaluating the videos with a view to embedded them in their - curriculum. The ER will learn new skills in qualitative research methodology and will develop a network of European Schools to evaluate new video production. Outcomes: This work will create a suite of dental videos that will be available to students - across Europe. They will be peer reviewed and made available via the Internet to students. The project will develop a framework for future video creation by educators and will allow translation to other disciplines. The ER will learn a range of - multidisciplinary skills including video creation, qualitative research methodology and have a suite of dental videos that will be made available to European Dental Schools. The host institution will benefit from how to embed ICT into dental - education and with new partners. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - c2LEARN - - - H2020-MSCA-IF-2016 - - - 748609 - - - - - OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN - - - EUR 166 156,80 - - - Antimatter gravity measurement: How does antihydrogen fall? - - - EUR 166 156,80 - - - Austria - - - Research Organisations - - Antimatter research has become a crucial sphere in the continuous attempt to understand the Universe and its laws. The only stable, neutral antimatter atom available for laboratory study is the antihydrogen. We here propose to - carry out a 30% measurement of the gravitational acceleration for antihydrogen, which will reveal the sign of gravity acting on antimatter, within the next two years. The principle is based on the rotation of a three grating moiré deflectometer, - coupled to a detector, and requires neither position resolution nor time-of-flight information for the through-going antihydrogen atoms. The realization of the measurement requires high quality simulations and the state-of-the art moiré - deflectometer, with gratings that are able to detect the annihilating antihydrogen atoms. The project goal will be reached through a series of software and hardware developments that are part of the implementation of the three work packages defined - in the proposal. The main deliverables are new, faster simulations for antihydrogen annihilation and novel technologies for instrumentation for inertial sensing and detection of antimatter. In a more general context, this project proposal addresses - the very fundamental question: do matter and antimatter fall in the same way? The Weak Equivalence Principle says that they must, but our understanding of antimatter is far from complete, with the baryon asymmetry in the Universe being one of the - greatest unsolved problems in physics. A successful outcome of the proposed work will accelerate the researcher's growth towards her career goal: becoming a mature experimental physicist. At the same time, the host institution will greatly expand its - influence in antimatter research and will benefit from new collaborators. - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Austria - - - ANGRAM - - - H2020-MSCA-IF-2016 - - - 748826 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 173 076 - - - Key Inorganics for Spintronics and MagnetoElectrics - - - EUR 173 076 - - - France - - - Research Organisations - - Magneto-electric (ME) materials have been attracting considerable interest for their potential application in e.g. data-storage. Up to now, applications have been hindered by the weakness of the polarization generated by the - ME effect. KISS-ME relies on the recent discovery by the host laboratory of inorganic compounds built on Low-Dimensional magnetic units. Dealing with 1D and 2D topologies carrying macrospins with large magnetization, they form the ideal playground - for enhanced ME properties. The applicant proposes to quantify the ME performances on such phases and on new specifically-designed ones. This will allow to deduce the ideal chemical/structural/magnetic context for giant ME. It is a prerequisite for - the prediction and synthesis of optimal multiferroics, limited so far by weak ME polarization and low temperature. Our multi-step strategy includes Design, Elaboration, Crystal Growth, Structural and Physical Characterization and theoretical modeling - of relevant low-D ME. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - KISS ME - - - H2020-MSCA-IF-2016 - - - 750971 - - - - - FUNDACIO CENTRE DE REGULACIO GENOMICA - - - EUR 158 121,60 - - - Reprogramming of elite B cells to induced hematopoietic stem cell with microRNAs and transcription factors - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - Generating Hematopoietic Stem Cells (HSCs) by Transcription Factor (TF) overexpression is of great interest in the stem cell field and promises considerable therapeutic potential. Among the systems described so far only one - study, using murine B cells, has led to the generation of transplantable induced HSCs (iHSCs), although at exceedingly low efficiencies and using combinations between 6 and 8 TFs. We propose here a new approach to generate iHSCs based on the use of - newly identified highly plastic “elite” type cells for reprogramming by the Yamanaka factors into induced pluripotent stem cells, generated by the transient exposure of B cells to C/EBPα. Hypothesizing that microRNAs could potentiate the effect of - TFs in HSC reprogramming we will also analyze the effects of microRNA overexpression. For this we will first analyze HSCs and different hematopoietic progenitors to identify differentially expressed microRNAs. Different combinations of selected - microRNAs will be cloned into inducible retroviral vectors together with hematopoietic TFs and used to infect “elite” CEBPα-primed B cells to screen for the induction, in vitro and in vivo, of iHSCs. The use of colony assays, cell surface marker and - transcriptomic analyses of the resulting cells, as well as transplantation into irradiated mice, will enable us to identify microRNAs and TFs combinations that induce HSC reprogramming. The heterogeneity of iHSCs will then be tested by single cell - expression analysis using RNA-seq. This project will provide new insights into the reprogramming of HSCs, the clinically most important type of adult stem cells, with potential medical applications. The proposed action will benefit the applicant’s - career through acquisition of scientific maturity and independence. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - miRStem - - - H2020-MSCA-IF-2016 - - - 747539 - - - - - FONDAZIONE ENI ENRICO MATTEI - - - EUR 180 277,20 - - - Mining, lobbying and efficient environmental policy - - - EUR 180 277,20 - - - Italy - - - Research Organisations - - Natural resources including raw materials are important for the European Union since they are a part of the base of the economy and simultaneously a large pollution and waste source. Sustainable development of the mining - sector extracting the raw materials calls for an economic analysis of environmental policy, which is the central theme of the MILO-project. The objective of the project is to investigate the optimal environmental policy of the mining sector with a - special emphasis on mining specific features and the choice of policy instruments under lobbying. Through its research results obtained using dynamic optimization methods, game theory and an array of dissemination and communication efforts, the - project will help to improve the currently applied policies in Europe. In addition to policy advice, the project will result in new insights on the formation of lobby groups and policy instruments by combining two game theoretical approaches, namely, - the common agency framework and coalition theory modeling. The researcher, who is trained in the theory of environmental policy instruments and dynamic optimization methods, will conduct the research and training in FEEM’s international and - interdisciplinary working environment and will be supervised by an expert in the research field. The project with its trainings improves his research and transferable skills, and extends his international networks through the host’s contacts and - through a research visit. By including versatile training-through-research, multiple dissemination and communication methods, public engagement through the MILO-webpage and blog, and networking the project has a strong impact on the researcher’s - career, on the future research collaboration as well as on the public interest. - - 2019-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - MILO - - - H2020-MSCA-IF-2016 - - - 748066 - - - - - FONDAZIONE PER L'ISTITUTO DI RICERC A IN BIOMEDICINA - - - EUR 265 840,20 - - - Neutrophil subtypes: distinct cellular targets for therapeutic intervention - - - EUR 265 840,20 - - - Switzerland - - - Research Organisations - - In cancer immunotherapy and vaccine field, considerable efforts have been invested to optimize the induction of effector T cells that, by recognizing tumor-specific or pathogen-associated antigens, control tumor cells or infections. - - - 2020-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Switzerland - - - TANTUMorNEUVACCINE - - - H2020-MSCA-IF-2016 - - - 750973 - - - - - UNIVERSITEIT VAN AMSTERDAM - - - EUR 165 598,80 - - - RNA localization in bacteria - - - EUR 165 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - In eukaryotic cells mRNAs can be localized to specific places within a cell to achieve protein synthesis with spatiotemporal control. Recently, I and others have shown that prokaryotes can also target mRNAs to specific parts - of the cell. However, these studies have been restricted to a limited number of mRNAs and were performed with Gram-negative bacteria, and due to the serendipitous nature of these discoveries and conflicting results, it is not clear how widespread - mRNA localization is in a bacterial cell and what conserved mechanisms are playing a role. To investigate this, I will first employ a novel CLIP-seq-inspired deep-sequencing-based approach to gain an unbiased view of mRNAs enriched at the cell - periphery and cell poles of the Gram-positive model bacterium Bacillus subtilis. This dataset will reveal the scope of mRNA targeting by the Signal Recognition Particle (SRP) and will reveal mRNAs that use another mechanism for cellular targeting. In - addition, classic CLIP-seq experiments will be used to identify mRNAs that use the cytoskeleton and other morphological proteins for targeting. As a complementary approach, I will assess the localization of mRNAs coding for different classes of - localized proteins (polar, cell division, cytoskeletal, membrane, secreted, motility, nucleoid and chaperone proteins) using the established fluorescence in situ hybridization (FISH) technique. Information obtained from these experiments will - subsequently be used to investigate the role of protein translation, RNA sequences, genome location and cell morphology in mRNA localization, to gain functional insight into the mechanisms responsible for this basic morphogenetic process. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - NucLoc - - - H2020-MSCA-IF-2016 - - - 749510 - - - - - FONDAZIONE ENI ENRICO MATTEI - - - EUR 168 277,20 - - - Infrastructural path dependence and irreversible investment in the integrated assessment of energy and climate policies - - - EUR 168 277,20 - - - Italy - - - Research Organisations - - The objective of this project is to analyse the role of path dependence due to infrastructural lock-in and irreversible investment decisions for the design of optimal energy and climate policies. The project brings together - several strands of economics research, namely macroeconomics, public economics, environmental and resource economics and risk and uncertainty, with climate change and energy economics into an integrated assessment. INFRACLIMATE is aimed to go beyond - standard models designed to study energy and climate policies, by incorporating irreversible investment decisions, inertia in energy systems and possibility of underutilization of capital stocks. The project has three main objectives. Firstly, to - carry out innovative research in the theoretical understanding of the interplay between irreversible investment decisions, high persistence in capital stocks and climate policies. Second, extending the existing Green Paradox literature by focusing on - how the irreversibility of investment decisions affect the supply of fossil fuels, and thirdly, to develop a fully-fledged integrated assessment model of economy, energy and climate to quantify the effects of climate policies on investment decisions - and the amount of stranded capital assets. A key ingredient of the analysis will be how various forms of uncertainty affect the interactions between investment decisions and climate policies. In doing so, the project will be able to provide a richer - characterization of investment decisions and their interaction with energy and climate policies, and to quantify welfare effects of different policy options. INFRACLIMATE is a timely and highly policy relevant project given Europe’s pledges to - emissions reductions, high infrastructural lock-ins in the extraction and power sector, and uncertainties about future technological innovations and government’s environmental policies. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - INFRACLIMATE - - - H2020-MSCA-IF-2016 - - - 747405 - - - - - Eidgenössische Technische Hochschule Zürich - - - EUR 175 419,60 - - - Colour and Kinematics of Quarks and Gluons inside Loops - - - EUR 175 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - The LHC era of fundamental physics presents a formidable challenge for theorists - the precision of Standard Model predictions should be improved by a factor of two. One of the major bottlenecks is the availability of two-loop - scattering amplitudes in quantum chromodynamics (QCD), which is largely limited to 2 -> 2 processes due to the daunting complexity of the perturbative series. The need for amplitudes of higher-multiplicity processes calls for new analytic insights - into the intricate structure of gauge theories. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - InsideLoops - - - H2020-MSCA-IF-2016 - - - 746138 - - - - - COPENHAGEN BUSINESS SCHOOL - - - EUR 200 194,80 - - - Cross-Cultural Experimental Analyses of Tax Morale - - - EUR 200 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - Tax evasion is a large and growing problem in almost all countries (Murphy’s 2012 report “Closing the European Tax Gap” estimated that “tax evasion in the European Union is approximatively € 860 billion a year”). This problem - is particularly extreme in Southern European countries as Italy, Spain and Greece. Recent experimental and survey analyses revealed that individual’s intrinsic motivation to pay taxes is not only influenced by tax rates and audit probabilities, but - also by social and cultural norms. Designing effective policies for reducing tax evasion thus requires understanding the behavioural aspects of tax compliance decisions. The previous experimental analyses on tax compliance were mainly carried out in - the Centre-North of Italy (Milan, Bologna and Rome) and assumed the taxpayer as an isolated individual. My proposed research, entitled “Cross-Cultural Experimental Analyses of Tax Compliance” (ChEATAX) will innovate by taking a broader perspective on - tax morale from the perspectives of both geography and level of analysis. In this way, ChEATAX can advance knowledge by addressing two long-standing gaps in the literature: the North-South discrepancies in Italian tax compliance, and the impact of - social norms and social interactions on tax morale. To isolate cultural effects as a factor in tax compliance, this aim will be pursued by collecting survey and laboratory data in Italy and Denmark, respectively representing Southern and Northern - European societies, and in the South and the North of Italy to capture disparities in Italian tax compliance. The outputs of this project will help understanding how different countries can establish and foster cooperation with taxpayers to enforce - tax compliance. - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - ChEATAX - - - H2020-MSCA-IF-2016 - - - 748062 - - - - - STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN - - - EUR 165 598,80 - - - Co-Translational Chaperone Action at the Single-Molecule Level - - - EUR 165 598,80 - - - Netherlands - - - Research Organisations - - The mechanism of protein translation by ribosomes has been the focus of recent single molecule investigations. Understanding translation at a single-molecule level is of particular interest to the life sciences and relevant - for various degenerative diseases. Although protein translation and folding are well studied subjects, cotranslational folding has been proven difficult to observe. How proteins adopt their native structure with efficient fidelity while being - synthesized by the ribosome remains largely unexplored. Using optical tweezers we recently measured the mechanics of synthesis and simultaneous folding in real-time, in the absence of chaperones. We found that cotranslational folding occurs at - predictable sequence locations, exerting forces on the nascent polypeptide chain. We showed that transient pauses of translation occur in particular locations along the protein sequence, facilitating native secondary structure formation. Several - crucial mechanistic questions concerning the effects of chaperones on co-translational folding remain unanswered: How do the chaperones trigger factor (TF), the major bacterial heat shock protein 70 (Hsp70/DnaK) and the GroEL/ES chaperonin system - affect cotranslational protein folding? Do they affect the translation rate? What effect do the chaperones have on initial hydrophobic collapse? When and how often do they (un)bind? How do these chaperones assure reliable and fast native folding - during protein synthesis? Here, I propose a combined optical tweezers and laser scanning confocal microscopy study to investigate the effects of chaperones on cotranslational folding in real-time, using the host's instruments, chaperones and - collaboration network, as well as my previously developed cotranslational assay and collaboration network. The group of Prof. S. J. Tans at AMOLF with its expertise and experience in single-molecule chaperone investigations is ideally suited for me - to pursue this study of cotranslational chaperone activity. - - 2019-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - COTCA - - - H2020-MSCA-IF-2016 - - - 745798 - - - - - UNIVERSITEIT VAN AMSTERDAM - - - EUR 177 598,80 - - - Microscopic Probes of Inflationary Cosmology - - - EUR 177 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - The theory of cosmic inflation is the current paradigm for early universe cosmology. I propose a research and training programme centered around two themes in inflationary cosmology. First, I will determine new signatures of - high-energy physics in inflation i) by finding new shapes of non-Gaussianity, in particular signatures from the tower of higher-spin states predicted in high-energy completions of gravity such as string theory, and also ii) by studying natural - extensions of the tensor sector, in particular higher spin fields with partial gauge symmetries, and the imprints left by these fields in tensor non-Gaussianity and in the cosmic microwave background (CMB) radiation. To achieve i) and ii), I will use - methods of field theory in curved backgrounds, as well as general symmetry properties of cosmological correlation functions. Second, I will study quantum instabilities in de Sitter space, as well as an analogue in flat space, a constant background - electric field. The instabilities will be determined by studying response functions and vacuum polarization in strong fields. The signatures proposed in the first theme will provide tools to perform particle spectroscopy and determine the field - content of inflation. The effects proposed in the second theme are a potential microscopic mechanism for the dynamics of inflation. - - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - INFPROBES - - - H2020-MSCA-IF-2016 - - - 751778 - - - - - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - - - EUR 185 076 - - - Voltage-sensing nanorods for super-resolution voltage imaging in neurons - - - EUR 185 076 - - - France - - - Research Organisations - - In the last decade, the rapidly developing optical imaging field has significantly improved our understanding of information processing in the brain. Although a number of promising tools have been designed, sensors of membrane - potential are lagging behind. In this project we aim to characterize an innovative voltage sensor for neurons that is fundamentally different from the existing ones. Our sensor is based on targetable voltage-sensing semi-conductor nanorods (vsNRs) - that self-insert into the neuronal membrane. The rods optically and non-invasively record action potentials at the single particle level, at multiple sites, and across a large field-of-view. Such vsNRs offer unique advantages, including: (1) large - voltage sensitivity, (2) ratiometric imaging based on a large spectral shift as function of voltage, (3) very fast response times in the range of ns, (4) very high brightness that affords single-particle detection, and (5) excellent performance in - the near-infrared spectral range. - - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - NanoVoltSens - - - H2020-MSCA-IF-2016 - - - 752019 - - - - - THE UNIVERSITY OF LIVERPOOL - - - EUR 195 454,80 - - - Parametrised Verification and Control - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - A variety of interesting systems -- servers that fail with a certain probability; biological models, where proteins are produced with a given rate; automotive and aeronautical systems -- displays stochastic behaviour. As a - fully automated method to analyse such systems, stochastic model checking is an important research area. - - 2019-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - PaVeCo - - - H2020-MSCA-IF-2016 - - - 753351 - - - - - VILNIAUS GEDIMINO TECHNIKOS UNIVERSITETAS VIESOJI ISTAIGA - - - EUR 130 779,60 - - - Sustainable Fibre-Reinforced Polymer Concrete (FRP-RC) Structures - - - EUR 130 779,60 - - - Lithuania - - - Higher or Secondary Education Establishments - - The corrosion problem of steel reinforcement severely limits the life-cycle sustainability of conventional reinforced concrete structures. This proposal focuses on the use of corrosion-free fibre-reinforced polymer (FRP) - reinforcing bars in lieu of steel reinforcing bars in concrete structures. Due to the currently incomplete understanding of serviceability aspects of FRP reinforced concrete (FRP-RC) structures, the existing design guidelines are not comprehensive, - and this restricts the applications of FRP-RC in real-life. The proposed project will investigate the fundamental issues of serviceability, fracture mechanics and time-dependent effects of FRP-RC to enable its practical usage. The objectives - encompass experimental investigation of deformation characteristics of FRP-RC specimens, derivation of constitutive models and establishment of deformation capacity of FRP-RC members, formulation of design guidelines in serviceability and development - of design aids for use by practising engineers. - - 2019-04-05, ongoing project - - - 2017-04-06 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Lithuania - - - SusFRPRC - - - H2020-MSCA-IF-2016 - - - 751461 - - - - - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - - - EUR 195 454,80 - - - Three-Dimensional Perovskite Oxides as Working ElectRochemical devices - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Three-Dimensional Perovskite Oxides as Working ElectRochemical devices (3D-POWER) will focus on utilization of perovskite oxides in combination with functional metallic materials to address the specific demands of sustainable - energy sector. The so formed 3D structures will serve as promising electrodes for the development of electrochemical devices such as solid oxide fuel cells, electrolyzers, batteries and supercapacitors. Specifically, within this project atomically - layered perovskites including La1-xSrxCo1-yFeyO3 (LSCF) and La1-xSrxMnO3 (LSM) will be synthesized through pulsed laser deposition and/or molecular beam epitaxy on pre-designed 3D substrates of Copper or Iron depending on growth conditions of - perovskites and eventual applications of the electrodes. These substrates will be uniquely fabricated by nanoscribe printing of metals to cast a 3D scaffold like support for the growth of perovskites and later will be chemically etched off. Further, - the performance of these perovskite constructs will be enhanced by depositing highly functional transition metal dichalcogenides (TMDs). This will serve as interconnects due to their excellent electrical, chemical and physical properties and overall - enhance device’s catalytic activity. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - United Kingdom - - - 3D-POWER - - - H2020-MSCA-IF-2016 - - - 751531 - - - - - UNIVERZA V LJUBLJANI - - - EUR 157 287,60 - - - Demonstration and implementation of an integrated process for the Plasma-Enhanced Chemical Solution Deposition of PMMA-multicomponent coatings on wood and wood-based substrates - - - EUR 157 287,60 - - - Slovenia - - - Higher or Secondary Education Establishments - - This action will implement the new Plasma-Enhanced Chemical Solution Deposition (PECSD) technique for coating of wood and wood-based substrates. This technique synergistically employs plasma-chemistry in the gas phase and - polymer chemistry in the liquid formulation, thus combining all benefits of conventional surface coatings and plasma-based deposition technologies. This will be carried out as a novel integrated process for the continuous coating of substrates - including three steps: - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Slovenia - - - PlasmaSolution - - - H2020-MSCA-IF-2016 - - - 745936 - - - - - BAUHAUS-UNIVERSITAET WEIMAR - CISM-LAB SRL - inuTech GmbH - TECHNISCHE UNIVERSITEIT EINDHOVEN - GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER - UNIVERSITY OF DURHAM - - - EUR 1 669 500 - - - Environmentally best practices and optmisation in hydraulic fracturing for shale gas/oil development - - - EUR 1 930 500 - - - Germany - Italy - Germany - Netherlands - Germany - United Kingdom - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This research brings together the complementary expertise of our consortium members to gain a better understanding of the physics in hydraulic fracturing (HF) with the final goal to optimize HF practices and to assess the - environmental risks related to HF. This requires the development and implementation of reliable models for HF, scaled laboratory tests and available on-site data to validate these models. The key expertise in our consortium is on modelling and - simulation of HF and all partners involved pursue different computational approaches. However, we have also some partners in our consortium which focus on scaled laboratory tests and one company which can provide on-site data. The choice of the best - model for HF still remains an open question and this research promises to quantify uncertainties in each model and finally provide a guideline how to choose the best model with respect to a specific output parameter. The final objective is to employ - these models in order to answer some pressing questions related to environmental risks of HF practices, including - - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Germany - - - BESTOFRAC - - - H2020-MSCA-RISE-2016 - - - 734370 - - - - - UNIVERSITAET ULM - - - EUR 159 460,80 - - - Cold Molecules in Cavities - - - EUR 159 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - Here we propose a radically new way to control chemical reactions on the quantum level. The Experienced Researcher (ER) will combine his long-standing expertise on cavity quantum electrodynamics (CQED) with the field of - ultracold chemical reactions, in which the host is one of the leading pioneers. We want to drive a photo-chemical reaction (photoassociation) within an optical cavity and in this way gain control over the reaction (objective 1). For this, we use the - control over spontaneous photon emission by an optical cavity, as has been done with single atoms. This paves the way towards novel fascinating effects like superradiant chemistry, where a chemical process is enhanced due to quantum statistics. - Furthermore, the optical cavity will be used as an ultrasensitive molecule detector of a new quality by detecting them without disturbing their quantum state (objective 2). This novel interdisciplinary combination of physics and chemistry will open - up a new research field, where the ER will demonstrate scientific innovation and independence. - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - CoMiC - - - H2020-MSCA-IF-2016 - - - 747160 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - LULEA TEKNISKA UNIVERSITET - OUTOTEC OYJ - - - EUR 1 596 958,56 - - - European Industrial Doctorate in future efficient minerals analysis, processing and training - - - EUR 1 596 958,56 - - - Ireland - Sweden - Finland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - MetalIntelligence proposes an EID in future efficient minerals analysis, processing and training. Transformational change caused by the third industrial revolution, which itself relies on extraction of raw materials, provides - the impetus. A resource-efficient EU is recognised as a societal challenge. However, the pathway from searching for mineral deposits to metal production is complex and involves a number of sectors (geosciences, chemical analysts, mining, processing, - metallurgy) that have tended to work in silos. Limited intersectoral collaboration has led to compartmentalised thinking which has become an impediment to improved resource and energy efficiency. - - 2020-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-EID - European Industrial Doctorates - - - Ireland - - - MetalIntelligence - - - H2020-MSCA-ITN-2016 - - - 722677 - - - - - UNIVERSITE DE LAUSANNE - UNIVERSITE DE LAUSANNE - - - EUR 2 499 969 - - - Resilience in ant societies - - - EUR 2 499 969 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Complex systems are found at all levels of biological organisation, from molecules to ecosystems. Despite the huge differences in scale, each of them has evolved homeostatic processes conferring resilience to external - perturbations. Ants provide an ideal system to identify behavioural responses allowing biological systems to recover from disturbance. The overall aim of this proposal is to identify the collective mechanisms responsible for this resilience. This - will be achieved by conducting both abiotic and biotic perturbations. Abiotic perturbations such as flooding frequently have major effects on the demography of the workforce, for example by whipping out all the foragers. We will therefore perform - highly controlled perturbations (e.g., targeted removal of worker groups) designed to induce compensatory changes in the behavioural trajectories of the remaining ants to test whether ants can deviate from their baseline behavioural trajectory to - mitigate the effect of external perturbations A major biotic challenge faced by all highly social species is the rapid spread of disease between closely-packed conspecifics. Because the kinetics of disease transmission in social groups depends upon - the structure of the interaction network, we will investigate how the prophylactic properties of the social interaction network emerge from the individual-level behaviours. Finally, we will perform controlled inoculations with a generalist fungal - pathogen to identify active individual-level behavioural responses that further hinder pathogen transmission. The proposed studies which capitalise on two recent methodological advancements (the development of sophisticated network analysis tools - and, a tracking system which allows unprecedented collection of behavioural data (e.g., millions of pairwise interactions) will make important contributions to our understanding of processes involved in resilience of complex systems and how animal - societies respond to stochastic environments. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Switzerland - - - resiliANT - - - ERC-2016-ADG - - - 741491 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 1 999 775 - - - Abstraction and Generalisation in Human Decision-Making - - - EUR 1 999 775 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Intelligent agents make good decisions in novel environments. Understanding how humans deal with novelty is a key problem in the cognitive and neural sciences, and building artificial agents that behave effectively with novel - settings remains an unsolved challenge in machine learning. According to one view, humans form abstract representations that encode latent variables pertaining to the high-level structure of the environment (a “model” of the world). These - abstractions facilitate generalisation of extant task and category information to novel domains. For example, an individual who can ride a bicycle, or speak Spanish, will learn more rapidly to ride a motorcycle, or speak Portuguese. However, the - neural basis for these abstractions, and the computational underpinnings of high-level generalisation, remain largely unexplored topics in cognitive neuroscience. In the current proposal, we describe 4 experimental series in which humans learn to - perform structured decision-making tasks, and then generalise this behaviour to input domains populated by previously unseen stimuli, categories, or tasks. Building on extant pilot work, we will use representational similarity analysis (RSA) of - neuroimaging (fMRI or EEG) data to chart the emergence of neural representations encoding abstract structure in patterns of brain activity. We will then assess how the formation of these abstractions at the neural level predicts successful human - generalisation to previously unseen contexts. Our proposal is centered around a new theory, that task generalisation depends on the formation of low-dimensional population codes in the human dorsal stream, that are scaffolded by existing neural basis - functions for space, value and number. The work will have important implications for psychologists and neuroscientists interested in decision-making and executive function, and for machine learning researchers seeking to build intelligent artificial - agents. - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - NEUROABSTRACTION - - - ERC-2016-COG - - - 725937 - - - - - UNIVERSITY OF GLASGOW - UNIVERSITY OF GLASGOW - - - EUR 149 995 - - - Acoustics for Next Generation Sequencing - - - EUR 149 995 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Since completion of the first human genome sequence, the demand for cheaper and faster sequencing methods has increased enormously. This need has driven the development of second-generation sequencing methods, or - next-generation sequencing (also known as NGS or high throughput sequencing). The creation of these platforms has made sequencing accessible to more laboratories, rapidly increasing the volume of research, including clinical diagnostics and its use - in directing treatment (precision medicine). The applications of NGS are also allowing rapid advances in clinically related fields such as public health and epidemiology. Such developments illustrate why sequencing is now the fastest-growing area in - genomics (+23% p.a.). The activity is said to be worth $2.5B this year, and poised to reach ~$9B by 2020. In any workflow, prior to the sequencing reactions, a number of pre-sequencing steps are required, including the fragmentation of the DNA into - smaller sizes for processing, size selection, library preparation and target enrichment. This proposal is specifically concerned with this latter area, namely DNA fragmentation – now widely acknowledged across the industry as being the most important - technological bottleneck in the pre-sequencing workflow. Our new method for DNA fragmentation – involving using surface acoustic waves will enable sample preparation from lower sample volumes using lower powers. It also has the potential to allow the - seamless integration of fragmentation into sequencing instrumentation, opening up the possibility of “sample to answer” diagnostics. In the near term this will enable the implementation of sample preparation pre-sequencing steps within the NGS - instruments. In the longer term, our techniques will also enable us to develop methods for field-based DNA sequencing – as may be required for determining “microbial resistance” and informing the treatment of infectious disease in the face of the - emergence of drug resistance. - - 2018-10-31, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - ACOUSEQ - - - ERC-2016-PoC - - - 737557 - - - - - DUBLIN CITY UNIVERSITY - UNIVERSITY COLLEGE LONDON - UNBABEL, LDA - THE COCHRANE COLLABORATION - - - EUR 229 500 - - - The INTERnAtional network on Crisis Translation - - - EUR 279 000 - - - Ireland - United Kingdom - Portugal - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - - We propose to establish an interdisciplinary, intersectoral and international research and innovation network in Crisis Translation, called INTERACT. Crisis Translation is understood here as the translation of written - information from one linguistic and cultural system to another in the context of a crisis scenario, with a view to enabling affected communities and responders to be prepared for crises, improve resilience and reduce the loss of lives. Due to the - transboundary nature of modern day crises, crisis communication must be multilingual and multilingual crisis communication is enabled through translation. Multilingual information access through translation addresses work programme aims such as - social fairness and democratic access to essential information for all. The primary focus of INTERACT is on health-related crisis content. The main objectives of the project are 1) to make meaningful and effective contributions to knowledge, - policies, expertise, training and technology that enable accurate and timely translation-enabled crisis communication, with a particular focus on health-related content; 2) to improve outcomes for crisis-affected and at-risk communities by - contributing to translation-enabled communication to, with and from those communities; 3) to enhance human skills, competences and cross-sectoral collaboration across academic, humanitarian, and industrial sectors involved in crisis translation. This - will be achieved by focusing on five main topics: crisis communication policy, comprehension in limited proficiency communities, crisis machine translation, citizen translator education, and ethics and through collaboration across academic, SME, NGO, - and Multinational partners. The contribution of INTERACT will be a much broader, better informed, innovative, much more impactful perspective on the challenges of crisis communication and the role of translation. - - 2020-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Ireland - - - INTERACT - - - H2020-MSCA-RISE-2016 - - - 734211 - - - - - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - - - EUR 1 999 999 - - - A Wearable Electronics Approach To Reduce Mortality in Epilepsy - - - EUR 1 999 999 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Epilepsy is a neurological condition that affects approximately 1% of the population (or over 50 million people in the world). Europe alone is home to 6 million people that suffer from epilepsy with one new case every minute. - In certain cases, healthy patients with epilepsy can die suddenly and unexpectedly. This is known as Sudden Unexpected Death in Epilepsy (SUDEP). SUDEP kills thousands of people in Europe every year. Unfortunately the mechanisms of SUDEP are not - known, which makes it unpredictable Individuals with refractory tonic-clonic or complex-partial seizures are at the highest risk of SUDEP. These comprise approximately one third of the population affected by epilepsy, i.e. in the order of 2 million - people in Europe. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - NOSUDEP - - - ERC-2016-COG - - - 724334 - - - - - TECHNISCHE UNIVERSITAET MUENCHEN - TECHNISCHE UNIVERSITAET MUENCHEN - - - EUR 2 000 000 - - - Constructing and powering nanoscale DNA origami motors - - - EUR 2 000 000 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Our goal is to advance the field of DNA nanotechnology by achieving directed transport on the nanoscale using robustly functioning synthetic motor units. To do so, we propose to construct spatially periodic, diffusive - mechanisms that have broken inversion symmetry and to subject these mechanisms to conditions away from thermal equilibrium. We will build on recent progress in creating complex DNA-based structures and construct various nanoscale rotary and - translational Brownian ratchet mechanisms that have well- defined degrees of freedom for motion within periodic and asymmetric energy landscapes. The mechanisms will be self-assembled from DNA origami components. We will use cryo-Transmission - Electron Microscopy (TEM) to evaluate and iteratively refine our structures. Conventional video-rate fluorescence microscopy, in addition to super-resolution microscopy, will be employed to study in solution and in real time the diffusive motion of - the mechanisms on the single particle level. We will introduce various deterministic or stochastic thermal, mechanical, or chemical perturbations to drive the systems away from thermal equilibrium. We will use laser heating and cooling to - experimentally test thermal and flashing ratcheting mechanisms; we will employ dissipative asymmetric fluxes arising in active matter as realized in high-density ATP-hydrolysing motility assays; and we will couple out-of-equilibrium chemical - reactions to the motion of our mechanisms. The ultimate goal of our work is to take insights from these experiments and create robustly functioning nanoscale motor units that can drive directed motion against external load and perform at levels - comparable to those of natural macromolecular motor proteins. Achieving this goal will create unprecedented technological opportunities, for example, to drive chemical synthesis, actively propel nanoscale drug- delivery vehicles, pump and separate - molecules across barriers or package molecules into cargo components. - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - DNA ORIGAMI MOTORS - - - ERC-2016-COG - - - 724261 - - - - - UNIVERSITEIT LEIDEN - UNIVERSITEIT LEIDEN - - - EUR 1 475 565 - - - Indigenous Knowledge in the Making of Science: Historia Naturalis Brasiliae (1648) - - - EUR 1 475 565 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project is an interdisciplinary study of the role of indigenous knowledge in the making of science. Situated at the intersection of history and anthropology, its main research objective is to understand the transformation - of information and practices of South American indigenous peoples into a body of knowledge that became part of the Western scholarly canon. It aims to explore, by means of a distinctive case-study, how European science is constructed in intercultural - settings. - - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - BRASILIAE - - - ERC-2016-STG - - - 715423 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - - - EUR 129 773,75 - - - 2D nanomaterials-based composite films for more efficient thermal conduction - - - EUR 129 773,75 - - - Ireland - Ireland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The aim of this proposal is to determine the economic and technical feasibility of using readily scalable technologies for the development of inexpensive and high performance solutions for heat dissipation for the high-end - automobile industry, as well as other markets including household appliances, injection moulding, advanced aircraft and pharmaceutical manufacturing, ranging from the actual fabrication protocols, down to a wide range of finite products. - - - 2018-05-31, ongoing project - - - 2016-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Ireland - - - TC2D - - - ERC-2016-PoC - - - 727420 - - - - - POTSDAM INSTITUT FUER KLIMAFOLGENFORSCHUNG - - - EUR 159 460,80 - - - Integrating climate impact and spatial microsimulation modelling for improved climate change adaptation decision-making - - - EUR 159 460,80 - - - Germany - - - Research Organisations - - Minimising the welfare cost of climate change requires effective adaptation policies. Consequently, the EU strategy on climate change adaptation prioritises the creation of ‘frameworks, models and tools to support - decision-making and to assess [the effectiveness of] various adaptation measures’. Accurate measurement of welfare cost is a prerequisite for effective policy prioritisation. The current state of the art quantifies welfare costs using aggregated - methodologies. This has been shown to bias cost estimation and does not capture the socioeconomic distribution of welfare impacts. This bias may therefore affect the effectiveness of adaptation measures. Integrating climate impact models (with which - Prof Lotze-Campen and the Potsdam Institute for Climate Impact Research [PIK] are experts) with Spatial Microsimulation (SM) modelling (with which the experienced researcher, Dr. Farrell, is an expert) provides a framework to estimate micro-level - welfare impacts and thus overcome these deficiencies. Furthermore, this project integrates these estimates into decision-making models to aid policy. - - - 2020-04-01, Grant Agreement signed - - - 2018-04-02 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - CLIMOD - - - H2020-MSCA-IF-2016 - - - 743582 - - - - - THE UNIVERSITY OF SHEFFIELD - CONSIGLIO NAZIONALE DELLE RICERCHE - GOETEBORGS UNIVERSITET - UNIVERSIDAD DE EXTREMADURA - CITY OF BRADFORD METROPOLITAN DISTRICT COUNCIL - STOCKHOLMS STAD - SHEFFIELD CITY COUNCIL - SOFTECO SISMAT SRL - SHAPING CLOUD LTD - - - EUR 283 500 - - - Promoting Sustainable Freight Transport in Urban Contexts:Policy and Decision-Making Approaches - - - EUR 283 500 - - - United Kingdom - Italy - Sweden - Spain - United Kingdom - Sweden - United Kingdom - Italy - United Kingdom - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Within a context of growing urban population, advances in urban logistics operations and improved local authority planning, especially in the field of the urban freight transport, can alleviate the associated negative - environmental and economic impacts occurring in cities. - - 2019-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - United Kingdom - - - PROSFET - - - H2020-MSCA-RISE-2016 - - - 734909 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - - - EUR 1 500 000 - - - Memory Engram Maintenance and Expression - - - EUR 1 500 000 - - - Ireland - Ireland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The goal of this project is to understand how specific memory engrams are physically stored in the brain. Connectionist theories of memory storage have guided research into the neuroscience of memory for over a half century, - but have received little direct proof due to experimental limitations. The major confound that has limited direct testing of such theories has been an inability to identify the cells and circuits that store specific memories. Memory engram - technology, which allows the tagging and in vivo manipulation of specific engram cells, has recently allowed us to overcome this empirical limitation and has revolutionised the way memory can be studied in rodent models. Based on our research it is - now known that sparse populations of hippocampal neurons that were active during a defined learning experience are both sufficient and necessary for retrieval of specific contextual memories. More recently we have established that hippocampal engram - cells preferentially synapse directly onto postsynaptic engram cells. This “engram cell connectivity” could provide the neurobiological substrate for the storage of multimodal memories through a distributed engram circuit. However it is currently - unknown whether engram cell connectivity itself is important for memory function. The proposed integrative neuroscience project will employ inter-disciplinary methods to directly probe the importance of engram cell connectivity for memory retrieval, - storage, and encoding. The outcomes will directly inform a novel and comprehensive neurobiological model of memory engram storage. - - 2022-01-31, ongoing project - - - 2017-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Ireland - - - MEME - - - ERC-2016-STG - - - 715968 - - - - - UNIVERSITA DEGLI STUDI DI SASSARI - UNIVERSIDAD DE BURGOS - HELMHOLTZ-ZENTRUM GEESTHACHT ZENTRUM FUR MATERIAL- UND KUSTENFORSCHUNG GMBH - MONOLITHOS KATALITES KE ANAKIKLOSI ETAIREIA PERIORISMENIS EVTHINIS - VLACHOS NIKOLAOS - UNIVERSIDAD DE CHILE - COMISION NACIONAL DE ENERGIA ATOMICA - - - EUR 702 000 - - - CO2 absorbing Materials Project- RISE - - - EUR 702 000 - - - Italy - Spain - Germany - Greece - Cyprus - Chile - Argentina - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - - CO2MPRISE - Excellence training in solutions for CO2 capture technology aims to bring together subject matter experts from the academic and non-academic sectors to develop new technologies in CO2 capture and conversion field. - - 2021-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Italy - - - CO2MPRISE - - - H2020-MSCA-RISE-2016 - - - 734873 - - - - - KOBENHAVNS UNIVERSITET - - - EUR 200 194,80 - - - Novel Release-on-demand micronutrient fertilisers for crops - - - EUR 200 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - In many important agricultural crops successful fertilisation with micronutrients can lead to substantial increases in diseases resistance, marketable yield, and improved nutritional quality of food and feed. However, the - plant availability of supplied micronutrients is usually too low due to the high reactivity of fertilisers under unfavourable soil conditions. - - 2017-07-31, Grant Agreement terminated - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - MicroFert - - - H2020-MSCA-IF-2014 - - - 659999 - - - - - THE UNIVERSITY OF EDINBURGH - - - EUR 195 454,80 - - - Extracellular vesicle-mediated delivery of long non-coding RNA: Implications for vascular repair and regeneration - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Background: The concept of extracellular vesicles (EVs) has drastically changed from the initial non-functional debris to the current of key mediators of paracrine signalling. The cargoes of EVs comprise all kinds of - macromolecules, and recent evidence has demonstrated the presence of long non-coding RNAs (lncRNAs) in such vesicles. These RNA molecules have numerous potential regulatory functions and results obtained so far guide us to presume a determinant role - in vascular cell differentiation, proliferation and repair. Besides, the increasing data emerging in the field are significantly changing the way in which we interpret molecular mechanisms driving cardiovascular diseases and offers a brand new set of - molecular targets for therapy. For all these reasons, study of lncRNAs in vascular biology and disease is state-of-the-art. - - - 2019-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - EV-LNC - - - H2020-MSCA-IF-2016 - - - 747287 - - - - - THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS - THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS - - - EUR 2 161 502 - - - Civil Law, Common Law, Customary Law: Consonance, Divergence and Transformation in Western Europe from the late eleventh to the thirteenth centuries - - - EUR 2 161 502 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - A highly significant division in present-day Europe is between two types of legal system: the Continental with foundations in Civil Law (law with an ultimately Roman law basis), and English Common Law. Both trace their - continuous history back to the twelfth century. The present project re-evaluates this vital period in legal history, by comparing not just English Common Law and Continental Civil Law (or “Ius commune”), but also the customary laws crucially - important in Continental Europe even beyond the twelfth century. Such laws shared many features with English law, and the comparison thus disrupts the simplistic English:Continental distinction. The project first analyses the form, functioning and - development of local, national, and supra-national laws. Similarities, differences, and influences will then be examined from perspectives of longer-term European legal development. Proper historical re-examination of the subject is very timely - because of current invocation of supposed legal histories, be it Eurosceptic celebration of English Common Law or rhetorical use of Ius commune as precedent for a common European Law. - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-ADG - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - CLCLCL - - - ERC-2016-ADG - - - 740611 - - - - - KATHOLIEKE UNIVERSITEIT LEUVEN - KATHOLIEKE UNIVERSITEIT LEUVEN - - - EUR 1 386 875 - - - Virtual building acoustics: a robust and efficient analysis and optimization framework for noise transmission reduction - - - EUR 1 386 875 - - - Belgium - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Achieving a sufficient sound insulation of buildings is a complex problem since multiple transmission paths are important, uncertainties can have a large effect, and acoustic performance requirements often conflict with - structural and thermal requirements. Furthermore, accurate vibro-acoustic modelling across the entire building acoustics frequency range presently requires a huge computational effort. As a result, the acoustic development of building systems is - usually based on general design rules, insufficiently accurate prediction models and many experimental prototype tests. Such development is costly and time consuming, and leads to suboptimal designs. This project therefore aims to develop an - efficient yet sufficiently accurate prediction framework for the acoustic design of building systems which takes all uncertainties into account and which opens the way for design optimization. Four fundamental breakthroughs are required. First, a new - approach to high-frequency subsystem modelling will overcome the limitations of the current statistical energy analysis paradigm and handle a high degree of geometric and material complexity. Second, a modelling framework for built-up systems will be - developed, which incorporates different component model types and which switches between them as the frequency increases. The third development consists of quantifying the combined effect of all uncertain parameters on the overall sound insulation - performance in a logically consistent and computationally efficient way. Finally, a robust optimization approach that spans the entire building acoustics frequency range and that accounts for all relevant non-acoustic performance criteria as well - will be developed. Each development will be complemented by showcase applications in building acoustics, yet the fundamental nature of the developments make that they will have a profound impact in all disciplines where the study and/or control of - mechanical wave propagation are important. - - 2022-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Belgium - - - VirBAcous - - - ERC-2016-STG - - - 714591 - - - - - LUNDS UNIVERSITET - - - EUR 173 857,20 - - - Speciation and hybridization: a sex chromosome perspective - - - EUR 173 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - How do new species arise and how do closely related species maintain their integrity despite hybridization? Notwithstanding the central position of these questions in the fields of evolutionary and conservation biology, few - biologists have provided answers. Here, I will address these questions using a multidisciplinary approach combining genomics, lab experiments and field work. The key objectives of this project is to determine the factors that lead to genomic - divergence between closely related and hybridizing species and characterise DNA sequence changes that are associated with pre- and postzygotic barriers to species exchange with emphasis on the role of the X chromosome. Training-through-research - includes a secondment to another lab to improve skills in animal breeding and experiments. This action will also generate new resources to the scientific community (a damselfly genomics toolkit), and efficiently disseminate knowledge to the public. - Due to its multidisciplinary approach and many opportunities for collaboration, executing this research program will provide new avenues of research for my future career as independent researcher within the EU. The excellent supervision and state of - art infrastructure at the host lab will ensure the successful execution of this project. - - 2020-02-29, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - Hybrid Conflicts - - - H2020-MSCA-IF-2016 - - - 753766 - - - - - UNIVERSITA COMMERCIALE LUIGI BOCCONI - UNIVERSITA COMMERCIALE LUIGI BOCCONI - - - EUR 1 499 375 - - - Social Mobility and Inequality across Italy and Europe: 1300-1800 - - - EUR 1 499 375 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The goal of SMITE is to improve our knowledge of long-term trends in social mobility, from the decades immediately preceding the Black Death of 1347-49 up until the eve of Industrialization. The objective is not only to - measure mobility, but also to understand its consequences for the economy and society at large. Very few data about preindustrial social mobility are available today, especially for southern Europe. SMITE will collect an extensive database about - social mobility, measured in different ways including: economic mobility across wealth classes and occupational mobility. Archival research will be concentrated on Italy where excellent sources exist, but the Italian case will be placed in the wider - European context. The few existing databases from all over the continent will be collected for comparison and direct research will be done on some regions of Europe beyond Italy, especially in France, Spain and the Low Countries. - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Italy - - - SMITE - - - ERC-2016-COG - - - 725687 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 183 454,80 - - - Streamlined Functionalisation of Nitrogen-containing Molecules by Palladium-catalysed C-H Activation - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Transition-metal catalysed C-H activation is a powerful tool to functionalise and derivatize organic molecules at seemingly inert sites. The strategy opens new efficient synthetic routes to existing molecules and provides - access to novel ones. Our aim is to develop palladium catalysed sp3 C-H activation technology for the synthesis of nitrogen heterocycles and for the derivatization of simple secondary amines to high value molecules. Our proposal will address demand - in the pharmaceutical industry for the efficient synthesis of nitrogen-containing molecules to aid medicinal chemistry and accelerate the drug discovery processes. - - 2019-03-09, ongoing project - - - 2017-03-10 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ACTPD - - - H2020-MSCA-IF-2016 - - - 747600 - - - - - THE UNIVERSITY OF EDINBURGH - THE UNIVERSITY OF EDINBURGH - - - EUR 1 999 155 - - - Classicising learning in medieval imperial systems: Cross-cultural approaches to Byzantine paideia and Tang/Song xue - - - EUR 1 999 155 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In the medieval Eurasian geopolitical space, Byzantium and China stand out as two centralised imperial orders that drew on seemingly unbroken, in fact purposely constructed, traditions of classicising learning. PAIXUE examines - in tandem, with equal focus on structural parallels and divergences, the conscious revival and subsequent dialectics of classicising learning in middle and later Byzantium (c.800–1350) and Tang/Song China (618–1279). Initially tied into aristocratic - culture, it became a tool by which the imperial state sought to monopolise prestige and access to power so as to effectively channel the activities of newly emerging burgeoning ‘middling’ strata into the service of empire. As time progressed, it was - also the basis upon which these new elites constructed novel forms of subjectivity that claimed authority and agency increasingly independent of the imperial state. - - 2022-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - PAIXUE - - - ERC-2016-COG - - - 726371 - - - - - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - - - EUR 159 460,80 - - - The Brain Dynamics of Human Fluid Intelligence - - - EUR 159 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - Human fluid intelligence is characterized by a structured sequence of cognition, resulting in efficient application of rules to novel problems. In the brain, metabolic neuroimaging and lesion studies have linked fluid - intelligence to a specific frontoparietal network, here called the multiple-demand (MD) network, comprising regions of lateral frontal, insular, dorsomedial frontal and parietal cortex. But how do MD functions determine fluid intelligence across - stages of cognition? My extensive expertise in electroencephalography (EEG) source analyses and neural pattern classification techniques will allow me to assess time-resolved neural representations of novel rules in MD and perceptual cortex as a - function of fluid intelligence, as well as the causal impact of MD cortex on earliest stages of perceptual encoding. Higher- and lower-intelligent subjects’ electrophysiological (EEG) and behavioural measures of novel rule implementation will be - systematically analysed. Non-invasive neural stimulation (transcranial magnetic stimulation (TMS)) will be used in combination with EEG to draw causal conclusions on the specific role of MD and perceptual cortices in human fluid intelligence. My - novel analysis approach may provide a new account on fluid intelligence: one aspect of low fluid intelligence may be the dysfunctional early filtering of task-relevant information in perceptual cortex, due to lack of top-down control from MD - cortices, leading to sensory overload on later processing stages. The proposal’s outcomes will be both of high academic and commercial interest. Understanding the brain signatures underlying fluid intelligence is essential for more specific and - cost-effective medical interventions. For example, decline of fluid intelligence due to healthy ageing is strongly correlated with high-cost medical conditions such as depression, which affect an increasing number of people in the ageing European - population. - - 2020-02-29, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - NEUROINTELLIGENCE - - - H2020-MSCA-IF-2016 - - - 752276 - - - - - THE UNIVERSITY OF WARWICK - - - EUR 195 454,80 - - - Tubular Supramolecular Polymer Brushes as Novel Therapeutic Materials - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The aim of this project is to develop supramolecular polymer brushes through the self-assembly of cyclic peptide/polymer conjugates into functional materials for applications as therapeutic polymers. The research program is - articulated around 1/the fabrication of supramolecular polymers of precisely controlled structures from peptide–polymer conjugate synthesis to self-assembly and 2/applying these supramolecular polymers to build delivery vehicles for therapeutic - applications. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - TSPBNTM - - - H2020-MSCA-IF-2016 - - - 747931 - - - - - FUNDACIO INSTITUT DE CIENCIES FOTONIQUES - - - EUR 158 121,60 - - - Topological physics in tunable optical lattices - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - The project Topological physics with disorder in tunable optical lattices aims at developing a new experimental setup to explore topological material properties and topological quantum phase transitions using cold atoms in optical lattices. - - 2017-05-31, Grant Agreement terminated - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - TOP-DOL - - - H2020-MSCA-IF-2014 - - - 657439 - - - - - UNIVERSITY OF NEWCASTLE UPON TYNE - - - EUR 195 454,80 - - - Sacred Landscapes in Late Byzantium - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - This interdisciplinary project will explore texts composed by the fourteenth-century Constantinopolitan Patriarch Philotheos Kokkinos, with a threefold focus on: - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SLLB - - - H2020-MSCA-IF-2016 - - - 752292 - - - - - ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE - - - EUR 183 454,80 - - - Deep Earth Elastic Properties and Effective Rheology - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The interface between the Earth’s rocky mantle and molten outer core, located 2900 km below the surface, is marked by a patchwork of enigmatic structures. These structures, revealed by anomalous reductions in the speed of - traveling seismic waves, are characterized by high density, partial melting, and low topographic heights (10-40 km above the core-mantle boundary). Due to the low seismic wave speeds, they are called UltraLow Velocity Zones (ULVZs). Since their first - discovery in the 90s, our understanding of the ULVZs has been based on seismic observations. The influence of microscale distribution of melt and minerals on the seismic signature and the internal structure of the ULVZs remain a challenging question - in geophysics. To address this question, this project will use a cross-scale approach to quantify the influence of partial melting and solid composition on the elastic properties and rheology of the UL-VZs based on a microstructural model. Using the - microscale constraints on the physical properties, the km-scale internal structure of the ULVZs will be simulated using a finite elements model. - - 2017-07-29, Grant Agreement terminated - - - 2015-07-30 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - DEEPER - - - H2020-MSCA-IF-2014 - - - 658330 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 941 499 - - - Metabolic Networks that Link Longevity to Reproduction in Response to Nutrition - - - EUR 1 941 499 - - - France - France - - - Research Organisations - Research Organisations - - In most western countries, life expectancy is increasing by 3 months a year. As the average age of the population increases, so too does the prevalence of age-related diseases such as cancer, cardiovascular and metabolic - diseases, and neurodegenerative disorders. An essential component of ageing research is to understand the biological mechanisms that contribute to the ageing process at the cellular and molecular levels. This has major implications not only for the - treatment of age-associated diseases but also for the promotion of healthy ageing. - - 2020-09-30, Grant Agreement terminated - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - France - - - MeLiLoN - - - ERC-2014-CoG - - - 647003 - - - - - KATHOLIEKE UNIVERSITEIT LEUVEN - KATHOLIEKE UNIVERSITEIT LEUVEN - THE UNIVERSITY OF EDINBURGH - THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - - - EUR 1 810 576 - - - The evolutionary dynamics of pathogen emergence and establishment: from Reservoir Detection to Outbreak Control - - - EUR 1 810 576 - - - Belgium - Belgium - United Kingdom - United States - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Extracted evolutionary and epidemiological information from pathogen genomes has grown into an important instrument across infectious disease research. By harnessing such information, molecular epidemiologists aim to shed - light on the origin and epidemic history of pathogens, from reservoir dynamics to emergence and adaptation to new hosts, and their spatiotemporal spread. However, despite the revolution in genome sequencing technologies and advances in statistical - methodology, key questions about pathogen emergence and establishment in human populations remain unresolved for major viral epidemics. When confronted with new viral outbreaks, such as the recent devastating Ebola virus epidemic, we also struggle to - deploy these technologies in a systematic and concerted way despite a critical need to support public health interventions. - - 2022-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Belgium - - - ReservoirDOCs - - - ERC-2016-COG - - - 725422 - - - - - THE JAMES HUTTON INSTITUTE - THE JAMES HUTTON INSTITUTE - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSITY OF DUNDEE - - - EUR 1 978 475 - - - Sensing soil processes for improved crop nitrogen bioavailability - - - EUR 1 978 475 - - - United Kingdom - United Kingdom - France - United Kingdom - - - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - - Food production is predicated on the application of nitrogen fertilisers, which can contribute significantly to the production of greenhouse gasses and eutrophication of agroecosystems. The use of nitrogen fertilisers must, therefore, be optimised. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - SENSOILS - - - ERC-2014-CoG - - - 647857 - - - - - INSTITUT SUPERIEUR DE L'AERONAUTIQUE ET DE L'ESPACE - - - EUR 138 807 - - - Designing Next-Generation Aircraft via High-Fidelity Computational Models and Optimization - - - EUR 138 807 - - - France - - - Higher or Secondary Education Establishments - - Air transportation is a crucial contributor to the world economy, and thus its continued growth is essential. However, environmental impact and the increase in fuel prices make sustainable aviation a challenge. To address this - challenge, we propose to develop state-of-the-art computational tools for the design optimization of next-generation airliners with unprecedented fuel efficiency. We will achieve this by leveraging the expertise of the researcher on high-fidelity - computational design of aircraft, together with Airbus’ vast experience in practical aircraft design, and the network of academics at ISAE. The proposed research is expected to make a lasting impact at Airbus by implementing new computational tools, - and by developing design concepts for the next-generation of aircraft. - - 2016-11-30, Grant Agreement terminated - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - NextGen Airliners - - - H2020-MSCA-IF-2014 - - - 658570 - - - - - THE UNIVERSITY OF WARWICK - THE UNIVERSITY OF WARWICK - SABANCI UNIVERSITESI - - - EUR 938 184 - - - Exposure to Political Violence and Individual Behavior - - - EUR 938 184 - - - United Kingdom - United Kingdom - Turkey - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project will explore how exposure to political violence in a civil conflict context impacts upon social, economic and political behavior of individuals. It has three legs. In the first leg I will analyze the association - between political and domestic violence. Specifically, I will test the hypothesis that those exposed to political violence are more likely to be perpetrators of domestic violence. In the second leg I will analyze whether exposure to political - violence impacts upon economic behavior. Specifically, I will analyze the impact of exposure on risk, time and social preferences, savings behavior, employment, and earnings. Finally, in the third leg I will look into political behavior. - Specifically, I will analyze the association between exposure to political violence and political participation and support, political tolerance, ideology, voting behavior, and party choice. The project will make use of a natural experiment setting - that the institutional setup and the long-running civil conflict in Turkey create. Turkey has a mandatory military service system that requires each Turkish man, when he comes to age, to serve in the army for about a year. Those drafted are first - subject to a basic training program and then, via a lottery, are randomly assigned to military bases all over the country to serve the rest of their terms. This means a young soldier can be sent to a military base in Eastern or Southeastern Turkey - where a bloody armed conflict between the Turkish armed forces and the insurgent organization PKK has been going on since August 1984, and thus, can get actively involved in the armed conflict. This is a natural experiment setting that randomly - exposes young Turkish males to political violence. In this project I aim to study whether and how that exposure impacts upon social, economic and political behavior of the exposed. To accomplish these goals, two independent, large-n survey studies - will be designed and conducted in Turkey. - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - EXPOVIBE - - - ERC-2015-STG - - - 677627 - - - - - FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION - - - EUR 175 419,60 - - - Circuit analysis of thalamic visual processing and its modulation by long-range projections - - - EUR 175 419,60 - - - Switzerland - - - Research Organisations - - The thalamus, whose anatomical history goes back two millenia, has long been recognized as the master relay for sensory information propagating to cortex and consciousness. Yet, it is indisputable that thalamic nuclei are much - more than simple relays but integrate different sensory modalities, bottom-up as well as top-down information. One elementary form of top-down modulation is attention, which selectively enhances behaviorally relevant information. Attentional - modulation occurs already at the thalamus by, yet, unresolved circuit mechanisms. My research specifically aims at (1) exploring circuits for long-range, top-down modulation of thalamic visual processing, (2) dissecting the circuitry underlying - attentional modulation, and (3) understanding basic rules of thalamic information processing. I will pursuit these three aims using an innovative combination of monosynaptic retrograde rabies tracing, optogenetics and deep 2-photon calcium imaging. - My experiments will focus on the lateral geniculate nucleus (LGN), which is the main connection between the optic nerve and the visual cortex, as well as on the thalamic reticular nucleus (TRN), which provides major inhibitory input to LGN and has - previously been implicated in attentional regulation. Notably, TRN deficits have been suggested to contribute to the clinical symptoms of schizophrenia. By rabies tracing, I will target channelrhodopsin to monosynaptic long-range inputs to the visual - thalamus. By GRIN-lens assisted 2-photon imaging I will quantify visual responses and search for signatures of attentional modulation that can be induced by optogenetic stimulation of specific inputs. This approach will allow me to quantify - attentional modulation of thalamic information-processing by specific long-range inputs, to dissect the underlying circuitry mechanisms and to contribute to a better understanding of thalamic computational power as well as its vulnerabilities. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - Thalamic Circuits - - - H2020-MSCA-IF-2015 - - - 707522 - - - - - FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION - - - EUR 175 419,60 - - - Transcription factor binding as a function of chromatin - - - EUR 175 419,60 - - - Switzerland - - - Research Organisations - - How the genomic blueprint of an organism is translated into cellular phenotype is a fundamental question in modern biology. The instructions need to be specifically regulated for cells to function. The regulation of the - readout of this information is not entirely written in the DNA sequence but also requires epigenetic directives like DNA and histone modifications. - - 2019-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - TFtoChromatin - - - H2020-MSCA-IF-2015 - - - 705354 - - - - - UNIVERSITE DE BORDEAUX - INSTITUT POLYTECHNIQUE DE GRENOBLE - UNIVERSIDADE DE AVEIRO - UNIVERSITE DU LUXEMBOURG - UNIVERSITE DE LIEGE - UNIVERSITE CATHOLIQUE DE LOUVAIN - TECHNISCHE UNIVERSITAT DARMSTADT - KARLSRUHER INSTITUT FUER TECHNOLOGIE - LUXEMBOURG INSTITUTE OF SCIENCE AND TECHNOLOGY - - - EUR 3 779 224,56 - - - European Joint Doctorate in Functional Materials Research - - - EUR 3 779 224,56 - - - France - France - Portugal - Luxembourg - Belgium - Belgium - Germany - Germany - Luxembourg - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - EJD-FunMat is a European Joint Doctoral programme in the field of functional materials research. - - - 2019-05-31, ongoing project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-EJD - Marie Skłodowska-Curie Innovative Training Networks (ITN-EJD) - - - MSCA-ITN-EJD - European Joint Doctorates - - - France - - - EJD-FunMat - - - H2020-MSCA-ITN-2014 - - - 641640 - - - - - INSTITUT BARCELONA D ESTUDIS INTERNACIONALS, FUNDACIO PRIVADA - - - EUR 158 121,60 - - - Security Paradoxes in the Great Lakes: Between the Military-Capable and the Good-Governed State - - - EUR 158 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - This project identifies security-governance paradoxes resulting from the European Union’s (EU) security practices in the Great Lakes region. Although this region has been declared of strategic importance for the EU, several - practices could undermine both the EU’s security and normative foreign policy goals. Firstly, military and security measures, to which the EU has contributed extensively, have militarised the region, creating new sources of violence. Secondly, the - aim to support military and security self-regulation could imply that the EU is transferring the attainment of security goals to the target states, thus losing some control and autonomy. Thirdly, though the EU has aimed to balance security and - normative goals, scholars have questioned the extent to which a military and security-driven agenda is effective and whether it represents an abandonment of the good-governance agenda. Three questions follow from here: Is the practice of supporting - military and security capacity undermining the good governance agenda? What implications does this have for EU’s normative commitments? And, how effective is this practice for achieving EU’s security goals? The research addresses and connects these - debates through two specific innovations. It advances the concept of the ‘military capable’ state, and it proposes an innovative practice-based methodology to explore the implications of this concept by linking it to patterns of security practices in - processes of intervention. Highlighting these paradoxes will offer important insights into the interconnection of security and normative goals in policy and implementation. - - 2017-09-30, closed project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - PARADOXGREATLAKES - - - H2020-MSCA-IF-2014 - - - 660933 - - - - - FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION - FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION - - - EUR 2 499 604 - - - Writing and editing of memories from acquisition to long-term consolidation - - - EUR 2 499 604 - - - Switzerland - Switzerland - - - Research Organisations - Research Organisations - - Nervous systems produce adaptive behavior, arguably their most important function, through learning and memory. Memories ensure that what is learned will be available for later retrieval. Upon the initial learning process, - synaptic plasticity important for memory consolidation is triggered within minutes, but whether, and in which form memories will be retained more permanently can be influenced by information and insights gained after the initial trigger. Learning and - memory have been studied extensively, but we still know very little about the mechanisms through which memories are shaped after acquisition. Here we hypothesize that instead of simply reflecting requirements to produce long-term memory traces, - cascades of plasticity processes induced at the time of acquisition might also reflect systems requirements for updating of new relevant information, as well as selection of potentially useful memories that need to enter the process of long-term - consolidation. - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Switzerland - - - MemoryDynamics - - - ERC-2015-AdG - - - 694086 - - - - - FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION - - - EUR 175 419,60 - - - Studying the role of the retrosplenial cortex in flexible learning - - - EUR 175 419,60 - - - Switzerland - - - Research Organisations - - An emerging view of cortical area function posits that instead of primarily accounting for sensory processing and motor control, cortical areas might mediate flexible handling of sensory information and motor planning through - learning and memory. In this project I propose to investigate this notion focusing on the function of retrosplenial cortex (RSC), a large, poorly understood and highly interconnected cortical area that interfaces with the hippocampal system. RSC has - a key role in memory, and is thought to control flexible use of contextual information; it accounts for earliest memory deficits in Alzheimer’s disease. - - - 2018-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - REFLEX - - - H2020-MSCA-IF-2015 - - - 707047 - - - - - FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION - FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION - - - EUR 1 998 557 - - - RNAi-mediated Epigenetic Gene Regulation - - - EUR 1 998 557 - - - Switzerland - Switzerland - - - Research Organisations - Research Organisations - - RNAi refers to the ability of small RNAs to silence expression of homologous sequences. A surprising link between epigenetics and RNAi was discovered more than a decade ago, and I was fortunate enough to be involved in this - exciting field of research from the beginning. It is now well established that endogenous small RNAs have a direct impact on the genome in various organisms. Yet, the initiation of chromatin modifications in trans by exogenously introduced small RNAs - has been inherently difficult to achieve in all eukaryotic cells. This has sparked controversy about the importance and conservation of RNAi-mediated epigenome regulation and hampered systematic mechanistic dissection of this phenomenon. - - 2021-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Switzerland - - - REpiReg - - - ERC-2015-CoG - - - 681213 - - - - - TECHNISCHE UNIVERSITAT DARMSTADT - TECHNISCHE UNIVERSITAT DARMSTADT - - - EUR 1 999 465 - - - Enhancing electrocatalysis in low temperature fuel cells by ionic liquid modification - - - EUR 1 999 465 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The commercialization of low temperature fuel cells is restricted by the high cost and low durability of cathode catalysts. Intense efforts have been devoted to tackle this issue by engineering the structure of Pt-based - catalysts. Herein, a novel concept towards enhancing the performance of low temperature fuel cell catalysts is proposed, namely by tuning the local active site microenvironment with an immobilized ionic liquid (IL) phase. As demonstrated by the - applicant in preliminary work, a suitable IL layer strongly influences the active catalytic site in a very promising manner, apparently via a highly complex interplay of solvent-, ligand- and electrostatic-stabilization effects. As the structural - versatility of ILs allows for rational engineering of this modification at molecular level, the proposed project aims for a full scientific exploration of the remarkable activation and stabilization effects in ORR, to enable the realization of an - innovative fuel cell cathode with dramatically enhanced performance. To achieve this ambitious goal, a sound fundamental understanding of the interaction of ILs with electrocatalytic sites will be derived by making use of the excellent research - infrastructure and longstanding experience in ionic liquid design and catalytic materials at our institute. To demonstrate the general applicability, the deduced principals will also be applied to CO2 electrochemical reduction. The approach will not - stop at the design of novel catalyst systems, but will address solutions to ensure long-term stability of the IL modification. To avoid IL leaching from the catalyst over time, the recent success of the applicant in the synthesis of novel core/shell - carbon materials will be employed. The IL will be synthesized in situ within a mesoporous core and the steric demanding ions fixed through a molecular sieving shell surrounding each catalyst particle. A model-assisted strategy will be applied for - optimization of the core/shell pore structures. - - 2021-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - IL-E-CAT - - - ERC-2015-CoG - - - 681719 - - - - - UNIVERSITA DEGLI STUDI DI MILANO - UNIVERSITA DEGLI STUDI DI MILANO - TECHNISCHE UNIVERSITAT DARMSTADT - - - EUR 2 409 209 - - - Noninvasive Manipulation of Gating in Ion Channels - - - EUR 2 409 209 - - - Italy - Italy - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - noMAGIC has the visionary goal of engineering genetically encoded ion channels, which can be remotely controlled (gated) by stimuli that penetrate deep into human tissue without negative side effects. The control over ion - channel activity by deep penetrating stimuli will revolutionize research in neurobiology and physiology as it paves the way for remote and genuine non-invasive control of cell activity in vivo. Synthetic channels, which can be gated by magnetic - fields (MF), near infrared (NIR) radiation or ultrasound (US) will be engineered in the frame of noMAGIC by three complementary work packages (WP1-3). Design and engineering of the channels will be performed in WP1 by reiterated steps of rational and - irrational design, high throughput screening and in vitro and in vivo functional testing. We have identified two sensor modules for MF and NIR radiation, respectively, which will be functionally connected to a channel pore for a remote control of - gating. For the US-gated channel we will engineer a channel pore that is maximally responding to local changes in the lipid environment induced by US. Design and engineering of channels will be complemented by a computational approach (WP2), which - analyses, from elastic network models, the mechanical connections in the channel pore and which extracts information on the forces, which are required to gate a channel by the three stimuli. The outcome of WP2 will provide general design rules for - synthetic channels with implications much beyond the present project. WP3 also contributes to the engineering effort in WP1 by a spectrum of avant-garde spectroscopic methods, which resolve structural changes of the channel proteins under the - influence of remote stimuli. These structural insights will greatly advance our understanding of structure/function correlates in composite ion channels and it will inspire the design and engineering of channels, which respond to remote stimuli. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Italy - - - noMAGIC - - - ERC-2015-AdG - - - 695078 - - - - - FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION - FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION - - - EUR 2 497 200 - - - Amygdala Circuits for Appetitive Conditioning - - - EUR 2 497 200 - - - Switzerland - Switzerland - - - Research Organisations - Research Organisations - - The project outlined here addresses the fundamental question how the brain encodes and controls behavior. While we have a reasonable understanding of the role of entire brain areas in such processes, and of mechanisms at the - molecular and synaptic levels, there is a big gap in our knowledge of how behavior is controlled at the level of defined neuronal circuits. - - 2020-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Switzerland - - - Amygdala Circuits - - - ERC-2014-ADG - - - 669582 - - - - - TECHNISCHE UNIVERSITAT DARMSTADT - TECHNISCHE UNIVERSITAT DARMSTADT - - - EUR 1 405 572,50 - - - Policy Learning of Motor Skills for Humanoid Robots - - - EUR 1 405 572,50 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The goal of SKILLS4ROBOTS is to develop a autonomous skill learning system that enables humanoid robots to acquire and improve a rich set of motor skills. This robot skill learning system will allow scaling of motor abilities - up to fully anthropomorphic robots while overcoming the current limitations of skill learning systems to only few degrees of freedom. To achieve this goal, it will decompose complex motor skills into simpler elemental movements – called movement - primitives – that serve as building blocks for the higher-level movement strategy and the resulting architecture will be able to address arbitrary, highly complex tasks – up to robot table tennis for a humanoid robot. Learned primitives will be - superimposed, sequenced and blended. - - - 2020-06-30, ongoing project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - SKILLS4ROBOTS - - - ERC-2014-STG - - - 640554 - - - - - TECHNISCHE UNIVERSITAT DARMSTADT - TECHNISCHE UNIVERSITAT DARMSTADT - - - EUR 1 446 875 - - - The origin of heavy elements: a nuclear physics and astrophysics challenge - - - EUR 1 446 875 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Where in the universe are heavy elements synthesized? How are these elements produced? These are two exciting and interdisciplinary questions in nuclear astrophysics today and will be investigated in my ERC project EUROPIUM. - The favored astrophysical sites are neutrino-driven winds following core-collapse supernovae and neutron star mergers, where extreme conditions enable the rapid neutron capture process (r-process). We will perform long-time multidimensional - simulations of these two scenarios and combine them with nucleosynthesis calculations. In neutron star mergers, the radioactive decay of neutron-rich nuclei triggers an electromagnetic signal known as kilonova. This was potentially observed in 2013 - after a short gamma ray burst, associated with a neutron star merger. We will simulate the neutrino- and viscous-driven ejecta from the disk that forms after the merger around the central compact object. In addition, we will investigate supernova - neutrino-driven winds that produce lighter heavy elements from strontium to silver. We will explore the impact of rotation, improved microphysics, and magnetic fields on the wind evolution and nucleosynthesis. Because the synthesis of lighter heavy - elements elements occurs closer to stability, the nuclear physics uncertainties will be reduced by experiments in the near future. This will uniquely allow us to combine observations and nucleosynthesis calculations to constrain the astrophysical - conditions and gain new insights into core-collapse supernovae. In nuclear physics, a new era for extreme neutron-rich isotopes is starting with new experimental facilities. Based on our simulations, we will study the impact of the nuclear physics - input (nuclear masses, beta decays, neutron captures, and fission) going beyond the state-of-the-art by providing r-process abundances with uncertainties. Comparing our results with forefront observations of the oldest stars will in turn provide new - insights about the origin of heavy elements. - - 2021-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - EUROPIUM - - - ERC-2015-STG - - - 677912 - - - - - UNIVERSITY COLLEGE LONDON - UNIVERSITY COLLEGE LONDON - - - EUR 2 495 563 - - - The origins of dendritic computation within mammalian neural circuits - - - EUR 2 495 563 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This proposal aims to address a simple question: what is the fundamental unit of computation in the brain? Answering this question is crucial not only for understanding how the brain works, but also if we are to build accurate - models of brain function, which require abstraction based on identification of the essential elements for carrying out computations relevant to behaviour. In this proposal, we will build on recent work demonstrating that dendrites are highly - electrically excitable to test the possibility that single dendritic branches may act as individual computational units during behaviour, challenging the classical view that the neuron is the fundamental unit of computation. We will address this - question using a combination of electrophysiolgical, anatomical, imaging, molecular, and modeling approaches to probe dendritic integration in pyramidal cells and Purkinje cells in mouse cortex and cerebellum. - - 2021-06-30, ongoing project - - - 2016-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - DENDRITECIRCUITS - - - ERC-2015-AdG - - - 695709 - - - - - FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION - FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION - - - EUR 2 500 000 - - - The interpretation of retinal activity by the visual thalamus. - - - EUR 2 500 000 - - - Switzerland - Switzerland - - - Research Organisations - Research Organisations - - Sensory systems of the brain inform cortical centers about the outside world via the thalamus. Despite its central location between the sensory periphery and the primary sensory cortex, the functional role of the thalamus in - sensory processing is still largely unknown. Understanding the role of thalamic circuits and their modulation by other brain areas is important for several reasons. First, in order to dissect the functional role of higher brain regions, such as - sensory cortical areas, it is critical that we understand what kind of input they receive from the thalamus. The thalamus takes information from several different sensory channels, carrying different sensory features. Whether these features are - simply relayed to higher centers, or perhaps recombined into new features in the thalamus, is not known. Second, as a central station in sensory processing, the thalamus is thought to gate behaviorally relevant sensory information. In addition to the - input from the sensory periphery, the thalamus receives input from several other brain regions. How these inputs modulate or gate sensory information in vivo is not well understood. Finally, in the case of the visual system, an important unmet - medical need is optic nerve degeneration caused by end-stage glaucoma, which leads to blindness. Here the input to thalamus is lost, yet the thalamic and cortical circuits are not severely affected. New methods to reactivate the thalamic neurons by - channeling visual information directly to these neurons may help to restore some visual capability after the loss of optic nerve fibers. - - 2020-10-31, ongoing project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Switzerland - - - RETMUS - - - ERC-2014-ADG - - - 669157 - - - - - FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION - FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION - - - EUR 2 136 969 - - - Readout of DNA methylation - - - EUR 2 136 969 - - - Switzerland - Switzerland - - - Research Organisations - Research Organisations - - DNA and chromatin modifications are essential for proper control of gene expression during development. How these marks alter transcriptional programs and modulate binding patterns of sequence specific transcription factors - (TF) remains poorly understood. This currently limits our interpretation of epigenomic maps towards their incorporation into predictive models of gene regulation. - - 2020-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Switzerland - - - ReaDMe - - - ERC-2014-ADG - - - 667951 - - - - - FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION - FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION - - - EUR 2 200 677 - - - The molecular basis of CULLIN E3 ligase regulation by the COP9 signalosome - - - EUR 2 200 677 - - - Switzerland - Switzerland - - - Research Organisations - Research Organisations - - Specificity in the ubiquitin-proteasome system is largely conferred by ubiquitin E3 ligases (E3s). Cullin-RING ligases (CRLs), constituting ~30% of all E3s in humans, mediate the ubiquitination of ~20% of the proteins degraded - by the proteasome. CRLs are divided into seven families based on their cullin constituent. Each cullin binds a RING domain protein, and a vast repertoire of adaptor/substrate receptor modules, collectively creating more than 200 distinct CRLs. All - CRLs are regulated by the COP9 signalosome (CSN), an eight-protein isopeptidase that removes the covalently attached activator, NEDD8, from the cullin. Independent of NEDD8 cleavage, CSN forms protective complexes with CRLs, which prevents - destructive auto-ubiquitination. - - - 2020-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Switzerland - - - CsnCRL - - - ERC-2014-ADG - - - 666068 - - - - - FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION - FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION - - - EUR 2 500 000 - - - Control of Action Diversification by Descending Motor CircuitsControl of action diversification by descending motor circuits - - - EUR 2 500 000 - - - Switzerland - Switzerland - - - Research Organisations - Research Organisations - - Movement is the behavioral output of the nervous system. Animals carry out an enormous repertoire of distinct actions, spanning from seemingly simple repetitive tasks like walking to much more complex movements such as - forelimb manipulation tasks. An important question is how neuronal circuits are organized and function to choose, maintain, adjust and terminate these many distinct motor behaviors. Recent technological advances in neuroscience have made it possible - to begin to unravel the links between the organization of specific neuronal circuit elements in the CNS and the control of movement, a topic that will be central to this research program. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Switzerland - - - Descent - - - ERC-2015-AdG - - - 692617 - - - - - RISE RESEARCH INSTITUTES OF SWEDEN AB - - - EUR 173 857,20 - - - Energy innovative food process for production of high quality frozen foods - - - EUR 173 857,20 - - - Sweden - - - Research Organisations - - COLDµWAVE aims to improve the research skills of Epameinondas Xanthakis by developing an innovative environmentally sustainable process for blanching and freezing vegetables with improved textural and nutritional quality at SP - -Technical Research Institute of Sweden. The study which will be carried out will involve the use of microwave electromagnetic irradiation (MW) for blanching and freezing of vegetables. COLDµWAVE will develop tailored equipment for MW blanching of - vegetables that has very high energy efficiency and no water consumption. Furthermore, this project will develop innovative pathways in freezing to improve the quality of frozen vegetables by exploring, in a new context, previous results acquired by - the fellow. The developed process will lead to improved quality characteristics compared to the conventional freezing. During this extensive study the fellow will gain valuable multidisciplinary experience and new theoretical and practical skills in - the areas of heat transfer modelling, energy accounting methods, food nutrition and quality measurements as well as life cycle assessment methods. The integrated proposed study will give the fellow the opportunity to develop further knowledge on - development of innovative processes having industrial importance and finally become a real specialist in the microwave assisted food blanching and freezing. The candidate will also learn to conduct research, to manage projects, communicate results - effectively, commercialise research, as well as an in-depth education in development of innovative processes which will contribute for an open mind to innovation and more successfully realisation of research ideas into commercial reality. - - 2017-04-30, closed project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - COLDmicroWAVE - - - H2020-MSCA-IF-2014 - - - 660067 - - - - - THE JAMES HUTTON INSTITUTE - THE JAMES HUTTON INSTITUTE - - - EUR 2 499 980 - - - Recombination in large genome crop plants - - - EUR 2 499 980 - - - United Kingdom - United Kingdom - - - Research Organisations - Research Organisations - - During meiosis, recombination (crossing-over, CO) drives the exchange of genetic materials and releases genetic diversity by creating new combinations of alleles within and among chromosomes. CO is exploited in plant breeding - through the generation of large populations of recombinants from which genetically improved individuals are selected. However in some economically important crops such as barley, the rate of improvement has plateaued. One hypothesis is that this is - due to constraints on the locations of CO. In large genome cereals CO is restricted to the ends of chromosomes, excluding approximately two thirds of the genome from the breeding process. - - 2020-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - SHUFFLE - - - ERC-2014-ADG - - - 669182 - - - - - FUNDACAO DA FACULDADE DE CIENCIAS DA UNIVERSIDADE DE LISBOA FP - - - EUR 220 882,50 - - - BIHC- Bio-inspired models of human crowds - - - EUR 220 882,50 - - - Portugal - - - Research Organisations - - With current consumer-grade personal computers, it is possible to display 3d virtual scenes with thousands of animated individual entities at interactive frame rates. Crowd simulations are, however, too often limited to - characters lacking individuality and wandering in an environment without a specific goal. This situation is particularly problematic in the field of cultural heritage in real-time simulations of the past where the realism of individual behavior is - critical. This proposal, through a collaboration across the computer science and the archaeology fields, seeks to address this problem. It aims at exploring bio-mimicking techniques in the development of a generative model for heterogeneity and - spontaneity in behavioral animation of crowds. More specifically, the goals can be defined as (i) the development of a bio-inspired model of agency for virtual humans (which upgrades a previous prototype, part of my earlier research), (ii) the - development of an authoring tool to interact with the parameters of that model and develop context-specific behaviors/animations, and finally (iii) the development of a proof-of-concept - the simulation of a historical environment, with the - assistance of non-programmers using the authoring tool developed earlier. - - 2017-12-31, closed project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Portugal - - - BIHC - - - H2020-MSCA-IF-2014 - - - 655226 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - ROYAL COLLEGE OF SURGEONS IN IRELAND - - - EUR 175 866 - - - Development of a chemotherapeutic gel for glioblastoma multiforme treatment - - - EUR 175 866 - - - Ireland - Ireland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Advanced nanotechnology-based materials offer new solutions to the challenges associated with the non-specific delivery of therapeutics that leads to ineffective treatments, especially in oncology. Currently, both therapeutic - and diagnostic molecules are administered systemically, increasing the likelihood of unwanted side effects. THERAGEL will develop a novel delivery system that enables selective, targeted local delivery of therapeutics and imaging agents. - Specifically, I will use this delivery system to design a therapy for the treatment of glioblastoma multiforme, the most aggressive form of brain cancer. THERAGEL will comprise a unique combination of advanced injectable polymeric depots and targeted - nanoparticles with both chemotherapeutic and imaging agent payloads (‘theranostic’ nanoparticle). The polymeric depots will provide a continuous release of free chemotherapeutic drug, with a tunable profile depending on the polymer composition, and - cancer-targeted nanoparticles that will release the theranostic cargo only after selective uptake by cancer cells. THERAGEL will advance the state of the art in nanomedicines through advances to the individual components of the developed delivery - system. This proposal represents a unique opportunity in the context of nanotheranostics for tailored chemotherapy, and means a significant step towards its clinical translation. The technologies developed will address three out of the six Horizon - 2020 Key Enabling Technologies themes, which are a key part of the programme funding strategy: Nanotechnology, Advanced Biomaterials and Advanced Manufacturing technologies. This research constitutes a highly multidisciplinary approach with large - impact in near future advanced therapies and with a great chance for collaboration and networking between European research groups and industrial partners. Combining my expertise in gated-materials with the host PI’s delivery systems development - experience will make this new direction possible - - 2018-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Ireland - - - THERAGEL - - - H2020-MSCA-IF-2015 - - - 708036 - - - - - FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION - FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION - - - EUR 2 859 560 - - - Transcriptional and Epigenetic Regulation of Totipotency in Mouse Early Embryos. - - - EUR 2 859 560 - - - Switzerland - Switzerland - - - Research Organisations - Research Organisations - - In mammals, fusion of two highly differentiated gametes gives rise to a totipotent zygote capable of developing into a whole organism. It coincides with translation and degradation of maternally provided transcripts, - initiation of global transcription called zygotic genome activation (ZGA), and “epigenetic reprogramming” of germline chromatin states into an embryonic state. The molecular mechanisms underlying this exquisite reprogramming of cell fate are barely - understood. - - - 2021-07-31, ongoing project - - - 2016-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Switzerland - - - Totipotency - - - ERC-2015-AdG - - - 695288 - - - - - TECHNISCHE UNIVERSITAT DARMSTADT - - - EUR 219 693,60 - - - ACcelerating Transition in Peri-Urban areaS in East Africa - - - EUR 219 693,60 - - - Germany - - - Higher or Secondary Education Establishments - - Behind statements and statistics about newly urbanized populations in Africa, behind maps of rapid and unregulated growth and numerous disaster/risk assessments there are real people with compelling tales of coping and - adapting capacities to urban challenges brought by the rapid transformation of cities. Their stories often contain more hope, ambition and imagination as portrayed in reports and scientific publications. Their ability to bounce back despite - disadvantageous ecological, economic and political settings implies a new form of normality framed outside traditional city development models. - - 2018-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Germany - - - ACTUS - - - H2020-MSCA-IF-2014 - - - 657784 - - - - - RIJKSUNIVERSITEIT GRONINGEN - MEDICAL RESEARCH COUNCIL - RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN - DANMARKS TEKNISKE UNIVERSITET - THE UNIVERSITY OF WARWICK - TECHNISCHE UNIVERSITAT DARMSTADT - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - KOBENHAVNS UNIVERSITET - BIOSYNTIA APS - DSM FOOD SPECIALTIES BV - THE FRANCIS CRICK INSTITUTE LIMITED - - - EUR 3 995 643,24 - - - RNA-based technologies for single-cell metabolite analysis - - - EUR 3 995 643,24 - - - Netherlands - United Kingdom - Germany - Denmark - United Kingdom - Germany - France - Denmark - Denmark - Netherlands - United Kingdom - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - - Metabolism is the foundation of all living organisms. While cells in a population are often phenotypically different, most of our current analytical approaches still probe metabolism only at the population level. Because - strong evidence exists that metabolic cell-to-cell heterogeneity has, for instance, disease relevance, researcher from MetaRNA will overcome this severe analytical limitation through exploiting exciting opportunities emerging from the RNA field. Such - synergy potential between the metabolism and RNA research fields has until today not been exploited, because they are separated from each other in Europe and worldwide. Through consequently missing research training programs we thus lack experts with - combined knowledge in metabolism and RNA. The aim of the MetaRNA proposal is therefore to establish a European Training Network (ETN) that educates specialists for academia and industry - fully trained at the interface of these two fields - in the - development and application of RNA-based sensors to investigate metabolism at the single-cell level, to apply these tools for novel biotechnological applications and to provide a framework for their future use in diagnostics and therapeutics. In - MetaRNA, eight research groups from the metabolic and RNA fields and six partners from the private sector join forces to create a platform of mobility and training to 15 early-stage researchers (ESRs), by means of customized research projects, - exchange of knowhow among researchers and partners, attendance to specialized courses, workshops and conferences, as well as training in complementary skills. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Netherlands - - - MetaRNA - - - H2020-MSCA-ITN-2014 - - - 642738 - - - - - UNIVERSITA DEGLI STUDI DI SALERNO - TECHNISCHE UNIVERSITEIT DELFT - UNIVERSIDADE DO MINHO - FUNDACION TECNALIA RESEARCH & INNOVATION - GESELLSCHAFT FUER MATERIALFORSCHUNG UND PRUEFUNGSANSTALT FUER DAS BAUWESEN LEIPZIG MBH - TECHNISCHE UNIVERSITAT DARMSTADT - - - EUR 468 000 - - - SUstainability-driven international/intersectoral Partnership for Education and Research on modelling next generation CONCRETE - - - EUR 504 000 - - - Italy - Netherlands - Portugal - Spain - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - SUPERCONCRETE is a synergetic cross-disciplinary international/intersectoral project addressing theoretical models for next-generation concretes, characterised by a significant sustainability enhancement for the construction industry. - - - 2019-06-30, ongoing project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Italy - - - SUPERCONCRETE - - - H2020-MSCA-RISE-2014 - - - 645704 - - - - - TECHNISCHE UNIVERSITAT DARMSTADT - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - FUNDACIO INSTITUT DE CIENCIES FOTONIQUES - THE QUEEN'S UNIVERSITY OF BELFAST - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - WEIZMANN INSTITUTE OF SCIENCE - LUPHOS GMBH - FASTLITE SARL - - - EUR 2 338 562,16 - - - High-Intensity Coherent Nonlinear Optics - - - EUR 2 338 562,16 - - - Germany - United Kingdom - Spain - United Kingdom - United Kingdom - Israel - Germany - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Optical laser-based technologies are a key technology of the 21st century. Extension of the range of scientific and commercial laser applications requires a constant expansion of the accessible regimes of laser operation. - Concepts from nonlinear optics, driven with ultra-fast lasers provide all means to achieve this goal. However, nonlinear optics typically suffer from low efficiencies, e.g. if high-order processes are involved or if the driving laser pulse - intensities must be limited below damage thresholds (e.g. in nonlinear microscopy of living cells, or nonlinear spectroscopy of com-bustion processes). Hence, we require methods to enhance nonlinear optical processes. The field of “coherent control” - provides techniques to manipulate laser-matter interactions. The idea is to use appropriately designed light-matter interactions to steer quantum systems towards a desired out-come, e.g. to support nonlinear optical processes. - - 2019-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - HICONO - - - H2020-MSCA-ITN-2014 - - - 641272 - - - - - AALBORG UNIVERSITET - - - EUR 627 840 - - - FrontierResearchCompentences@CNAP - - - EUR 1 255 680 - - - Denmark - - - Higher or Secondary Education Establishments - - Chronic pain is a key societal challenge affecting one out of five adults and is in general poorly treated. This programme, FrontierResearchCompentences@CNAP (FRESCO@CNAP), aims to install 8 early stage researchers (ESRs) in a - Centre-of-Excellence (CNAP) conducting frontline research on novel tools for identifying and modulating human pain mechanisms. - - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2016 - Co-funding of regional, national and international programmes - - - MSCA-COFUND-DP - Doctoral programmes - - - Denmark - - - FRESCOatCNAP - - - H2020-MSCA-COFUND-2016 - - - 754465 - - - - - THE JAMES HUTTON INSTITUTE - - - EUR 183 454,80 - - - The mechanism of acquired thermotolerance in potato - - - EUR 183 454,80 - - - United Kingdom - - - Research Organisations - - For many commercial potato cultivars, tuber yield is optimal at average day time temperatures in the range of 14-22˚C. Further rises in ambient temperature can reduce or completely inhibit potato tuber production, with - damaging consequences for both producer and consumer. Despite centuries of potato breeding, high temperature tolerance has not been significantly improved. Targeted breeding approaches are hampered by a lack of knowledge on the molecular mechanisms - of how plants perceive and translate high temperature into relevant acclimation responses. Although in recent research we have identified genotypes that can yield well under elevated temperatures, we have not yet dissected which responses to elevated - temperature are the most critical for yield. Thus the objectives of ACQUIRE are: to develop a robust screen to assay for acquired thermotolerance in potato; to test potato genotypes and transgenic lines for variation in the acquired thermotolerance - response; to determine transcriptional and metabolite profiles associated with acquired thermotolerance; to introgress beneficial alleles of a potato heat tolerance gene (StHot1) to develop Nearly Isogenic Lines with improved acquired thermotolerance - characteristics; to assess the impact of acquired thermotolerance on tuber yield in a range of genotypes. The project will serve a training vehicle for an experienced researcher to enhance her portfolio of research skills and so increase their - ability to innovate in this important area of food security. The experienced worker will add an extra dimension to current research activities in the host organisation by sharing her current expertise. The outcomes will be of commercial and societal - interest and a raft of measures will be taken to ensure thorough dissemination of the project activities. The project will leave the experienced worker well-qualified to achieve professional maturity and will have a legacy of collaboration and new - research avenues to be explored. - - 2018-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ACQUIRE - - - H2020-MSCA-IF-2015 - - - 702121 - - - - - UNIVERSITY OF LIMERICK - - - EUR 1 840 800 - - - Advanced Learning in Evolving Critical Systems - - - EUR 3 681 600 - - - Ireland - - - Higher or Secondary Education Establishments - - Globally, software-based systems are increasingly important to economic activity and to the normal functioning of our everyday lives. The scope, scale and interconnected nature of such systems are increasing rapidly, with the - potential consequences of failure, security breaches or malfunction becoming a growing cause of concern. Evolving Critical Systems (ECS) that change over time (“evolving”), and strategically important to their users (“critical”), are increasingly - prevalent in software development, from business-critical systems (e.g. airline websites) to safety-critical systems (e.g. automotive braking control system). - - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2016 - Co-funding of regional, national and international programmes - - - MSCA-COFUND-FP - Fellowship programmes - - - Ireland - - - ALECS - - - H2020-MSCA-COFUND-2016 - - - 754489 - - - - - UNIVERSIDAD DE GRANADA - - - EUR 2 124 000 - - - Attracting and Encouraging Triple I Talent Mobility - - - EUR 4 248 000 - - - Spain - - - Higher or Secondary Education Establishments - - Athenea3I is an innovative regional wake-up call focused on attracting highly talented researchers to Granada (Andalusia region, Spain) in order to benefit their research career with International, Interdisciplinary and - Intersectorial opportunities. This innovative fellowship programme offers the experienced researchers an outstanding opportunity to develop new skills and competences, enriched with a personalized and pioneering career mentoring plan. It also - includes research periods at some of the most distinguished outstanding institutions around the world, and optional secondments in regional, national and international companies. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2016 - Co-funding of regional, national and international programmes - - - MSCA-COFUND-FP - Fellowship programmes - - - Spain - - - Athenea3I - - - H2020-MSCA-COFUND-2016 - - - 754446 - - - - - NVISION IMAGING TECHNOLOGIES GMBH - UNIVERSITAET ULM - - - EUR 96 462,30 - - - Translating quantum sensing into cost-effective molecular imaging - - - EUR 96 462,50 - - - Germany - Germany - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - The ability to recognize molecular processes using novel imaging techniques is of fundamental importance for medicine, biology and biochemistry in the 21st century. Non-invasive molecular imaging has gained widespread use in - patient management of cancer, life-science and medical research, as well as drug discovery and development. The capability of non-invasive metabolic profiling is expected to impact dramatically patient management for socioeconomically relevant - diseases. Spatially-resolved observation of metabolites will be key for enabling more accurate staging of diseases by direct assessment of the underlying impact on the metabolism. Quantification of, for example, the perturbation of the myocardial, - tumor, or neural substrate metabolism will most likely revolutionize staging and management of diseases in cardiology, neurology, oncology and other fields. - - - 2018-10-31, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-04-2016-2017 - FET Innovation Launchpad - - - CSA - Coordination and support action - - - Germany - - - QUSMI - - - H2020-FETOPEN-4-2016-2017 - - - 754346 - - - - - MAGYAR TUDOMANYOS AKADEMIA CSILLAGASZATI ES FOLDTUDOMANYI KUTATOKOZPONT - - - EUR 146 239,20 - - - The initial 244Pu abundance of the Solar System - - - EUR 146 239,20 - - - Hungary - - - Research Organisations - - The proposed project is a crossroad of noble gas cosmochemistry, geochemical modelling and astrophysics. We will obtain a best estimate of the initial 244 Plutonium content of the Solar System at the time when the first - condensed mineral assemblages formed in the hot solar nebula. We will apply this value to model the volatile depletion history of the silicate Earth and to produce the first self-consistent estimate on the timing of the last addition of matter - produced in rapid neutron capture processes (r process) to the Solar System. 244 Pu is an r-process- only short lived radionuclide that goes through spontaneous fission to produce Xenon isotopes and in principle the 244 Pu-Xe system can be used as - chronometer to date early volatile loss events in Solar System solids. We propose a comprehensive experimental approach to study noble gases in combination with Nd (similarly volatile to Pu) and U (more volatile than Pu) abundances on a complementary - set of samples that is adequate to explain the possible variation in the initial Pu/U ratio in different meteorites and early condensed mineral assemblages and to evaluate the applicability of the chronometer. While the Experienced Researcher is an - expert in noble gas geochemistry and has experience in geochemical modelling, she will gain the knowledge on cosmochemistry and stellar nucleosynthesis required to interpret and discuss the new results produced in this project. The individual - fellowship will help her start her early career as a postdoc and provide a crucial mobility to build a network in Europe and do research with high impact. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Hungary - - - IPUSS - - - H2020-MSCA-IF-2016 - - - 753276 - - - - - UNIVERSITEIT VAN AMSTERDAM - - - EUR 165 598,80 - - - A Place for the Asylum Seekers. European migration policies and their socio-spatial impacts - - - EUR 165 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - In the past two years the European Union has seen an enormous influx of migration. More than 1 million people arrived by boats in 2015 and more than 230,000 people in the first six months of 2016. - - 2020-02-29, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - PASS - - - H2020-MSCA-IF-2016 - - - 752021 - - - - - UNIVERSITY COLLEGE LONDON - - - EUR 195 454,80 - - - Modulation of Basket cell microcircuits in cerebellar cortex paroxysmal ataxia disorders - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The episodic ataxias are a group of hereditary conditions with recurring paroxysms of cerebellar dysfunction. They are rare; however they share important similarities to other more prevalent paroxysmal disorders such as - migraine and epilepsy. The prototypic cerebellar cortex paroxysmal disorder is Episodic ataxia 1 (EA1), which is linked to dominantly inherited missense mutations in the Kv1.1 potassium channel subunit. Work from an animal model harbouring a human - EA1 mutation reveals altered synaptic function at basket cell terminals in the cerebellar cortex. However how EA1 mutations affect basket cell regulation of Purkinje cell firing is unclear, possibly due to unforeseen changes in a specialized - inhibitory structure called the pinceau. Furthermore the mechanism whereby local synaptic deficits extend to global cerebellar cortex network dysfunction during attacks of incoordination is unknown. This MSC research action aims to understand these - processes using a combination of cutting edge in vitro and in vivo techniques. Using advanced electrophysiology techniques, I will assay basket cell pinceau function in mouse models of EA1, then using multi-photon and conventional microscopy I will - map local basket cell microcircuits. Finally building on in vitro experiments I will assay candidate small molecule therapies in vivo, both with electrophysiology and with behavioural test of cerebellar coordination. The project allows me to train in - state-of-the-art in vitro and in vivo methods while drawing on my extensive background in neuropharmacology, biochemistry electrophysiology. This research action will also advance our understanding of paroxysmal neurological disorders and identify - new therapeutic targets. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - BaskAtax - - - H2020-MSCA-IF-2016 - - - 753796 - - - - - THE UNIVERSITY OF BIRMINGHAM - - - EUR 183 454,80 - - - MEMory processing in the human ENTOrhinal cortex - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Deeply embedded in the medial temporal lobe (MTL) memory system, the entorhinal cortex (EC) is a small yet potentially key region for intact memory. While a series of recent ground-breaking findings in rodents point towards a - pivotal role of EC in spatial navigation, thought of as an evolutionary precursor to memory, little is known about its precise contribution to episodic memory in humans. Building on preliminary evidence that EC subregions may be specialised for - different stimulus types and/or different memory processes, MEMENTO proposes a systematic investigation of memory function in the human EC. The action combines state-of-the-art high-resolution and ultra-high field functional magnetic resonance - imaging (fMRI) with advanced analysis techniques to assess how these EC subregions support material-specific memory processing on four levels of resolution: the laminar level, the subregion level, the system level, and the behavioural level. MEMENTO - is highly collaborative: it brings together expertise of the ER (high-resolution fMRI of entorhinal cortex subregions), the host supervisor (functional dynamics of the MTL, advanced fMRI analysis), and the partner organisation (ultra-high field - fMRI). Given that the EC is one of the first structures affected in Alzheimer’s disease, the project results have great potential to stimulate important clinical implications. The ER will advance her research profile through highly transferable - experience not only with cutting-edge methods, but also with managing and engaging in scientific and public communicative events. This will qualify her to lead her own research group upon returning. - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - MEMENTO - - - H2020-MSCA-IF-2016 - - - 752557 - - - - - NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU - - - EUR 196 400,40 - - - INnovation through bIg daTa and socIal enTreprEneurship - - - EUR 196 400,40 - - - Norway - - - Higher or Secondary Education Establishments - - The power of big data and their applications is evident through the enormous attention they have received over the past few years, with the majority of the research focusing on solving technical and business problems. However, - the challenge remains on how to harness the potential of big data in order to come up with innovative solutions on various societal problems. Big data has the potential to change the way entrepreneurs, as well as the other stakeholders of a social - ecosystem, take decisions, and develop new paths to create social innovation (SI) by taking informed/data-driven decisions. Nonetheless, there is limited understanding on how social ecosystems need to change to embrace the advancement that big data - entails. The purpose of INITIATE is to institutionalize INnovation through bIg daTa and socIal enTreprEneurship, and to examine how to successfully exploit big data towards achieving social good and sustainable change. INITIATE will build on the - current state of the art, and go beyond it by merging and extending the findings with insights from the different stakeholders involved in the SI process (entrepreneurs, policy makers, social innovators). The project will be based on a rigorous - research process consisting of systematic literature review and empirical investigations and it will develop and test a framework of best practices. Interested stakeholders will use the framework as a roadmap to successfully exploit big data for SI. - INITIATE will offer practical and theoretical implications through the development of prototype applications which will clearly showcase the impact of big data on addressing societal challenges. Through INITIATE both the researcher and the host - institution will benefit by the transfer of knowledge, and the researcher will develop his skills further and acquire new ones. The host will benefit by the researchers’ developed knowledge, especially since this is consistent with the department’s - goals and strategic focus areas. - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Norway - - - INITIATE - - - H2020-MSCA-IF-2016 - - - 751510 - - - - - UNIVERSITY OF SUNDERLAND - - - EUR 195 454,80 - - - Lean data management for maintenance value - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The possibilities of data-based maintenance management as well as interconnected, smart, and autonomous assets have been discussed lately but in practice there are still a number of major problems regarding e.g. the amount, - quality, integration, and exploitation of maintenance data. In LeaD4Value these problems are addressed through lean maintenance data management to realise increased business value. Contrary to the Big Data hype, the idea here is to focus on the data - decision support tools to be constructed based on analytical modelling and statistical analyses. Data will be collected from computerized maintenance management systems and enterprise resource planning systems of the two seconded companies, as well - as from some of their employees via surveys and interviews. The results include e.g. a map of data exploitation paths, a process model, and a performance measurement system for lean maintenance data management. These tools can be used to reveal - unnecessary maintenance tasks and data collection, missing data collection, or potential to increase the business value of maintenance. The role of world-class maintenance is highlighted in European manufacturing, because a majority of new - production-related investments are directed to other continents. The proposed work is multidisciplinary by nature, combining aspects of business value management, reliability and maintenance engineering, and data sciences. The multidisciplinary view - is needed, for asset management is challenged by maintenance engineers and managers understanding the technical aspects of maintenance but being unable to communicate these to the company decision makers in terms of business value. Too often this - leads to short-sighted decisions. The project will expand the competences of the fellow in multiple disciplines, and provides international experience in science and business. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - LeaD4Value - - - H2020-MSCA-IF-2016 - - - 751622 - - - - - NATURAL HISTORY MUSEUM - - - EUR 183 454,80 - - - Phenotypic and lineage diversification of natricine snakes - - - EUR 183 454,80 - - - United Kingdom - - - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - The NATRICINE project is a study of the macroevolution of a major group (240 extant species) of snakes. Natricines originated in Asia and dispersed into N America, Africa and Australasia. They are diverse, with repeatedly - evolved surface, burrowing and aquatic ecotypes. The overarching project aim is to determine the extent to which lineage and phenotype diversification is impacted by dispersal to new regions (potentially providing ecological opportunity) and by - evolutionary transitions between ecotypes. The overarching aim will be tackled via four main research objectives: molecular phylogenetics to determine the interrelationships among >70% of all natricine species; historical biogeography to identify - ancestral areas and the location and timing of major dispersal events; phenotypic disparity and diversity analyses to quantify the main axes of natricine variation in time and space; quantitative analyses to test whether different ecotypes and - geographical groups have undergone different rates of lineage and phenotype diversification. These four objectives will be tackled in four work packages. The topic is novel and the approach is innovative in combining cutting-edge techniques including - amplification of DNA sequences from historical museum specimens, quantifying shape variation using the latest surface and microCT scanning approaches, and model-based analyses of trait and lineage evolutionary rate shifts. The project will be - undertaken by an early-career postdoctoral researcher, who has expertise and solid grounding in Asian reptile systematics, ecology and evolution, but who requires training in advanced Next Generation Sequencing, 3D imaging and macroevolutionary - quantitative analysis. The fellow will also receive training in public engagement, project management, student supervision and grant writing. This training will establish the fellow as a prominent vertebrate biologist who will lead European-Indian - collaborative biodiversity research for years to come. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - NATRICINE - - - H2020-MSCA-IF-2016 - - - 751567 - - - - - NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU - - - EUR 196 400,40 - - - Effects of global change on the social behaviour of marine organisms - - - EUR 196 400,40 - - - Norway - - - Higher or Secondary Education Establishments - - The IPCC projects a 0.2-0.3 unit decrease in oceanic pH and a concurrent 1.0-3.7°C increase in sea surface temperature by 2100. These changes will have considerable impacts on marine organisms and are a threat to European and - global biodiversity, food security, and socioeconomic productivity. While physiological impacts associated with marine global change have been well documented, behavioural impacts are less well known, even though behaviour has a major influence on - the structure and function of marine communities. Furthermore, of the documented behavioural changes associated with global change, social behaviours - which play a key role in the survival and persistence of marine animals – are largely ignored. - This project thus aims to advance current knowledge of global change biology by testing hypotheses pertaining to the impacts of ocean acidification and warming on the social behaviour of marine organisms spanning a wide range of taxa – from - invertebrates to fish. Herein, it is hypothesized that predicted near-future (i.e., 2100) CO2 and temperature conditions will alter the social behaviour of crustaceans (shrimp shoaling), echinoderms (urchin and sea star aggregations), and fish - (stickleback shoaling). This project will also test for physiological mechanisms underpinning global change-induced behavioural changes (GABAA functioning), as well as transgenerational effects (transgenerational acclimation in stickleback shoaling - behaviour). The training, mentorship, and practical experience associated with this project will provide the fellow with the skills and competency to become an international leader in global change biology and marine animal behaviour. Furthermore, - the knowledge generated by this project will answer critical questions in global change biology, which can be used by scientists, policy makers, stakeholders, and the general public, and will contribute to a much needed unifying theory of how global - change will affect marine species. - - 2020-03-31, Grant Agreement signed - - - 2018-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Norway - - - GlobChangeBehav - - - H2020-MSCA-IF-2016 - - - 752813 - - - - - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - - - EUR 183 454,80 - - - In vitro reconstitution and single cell analysis of the Shigella-septin cage. - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Autophagy, an intracellular degradation process, is an important defence mechanism against pathogenic bacteria, including the Gram-negative enteroinvasive human pathogen Shigella flexneri. Work has shown that septins, a - component of the cytoskeleton that interacts with membranes, entrap cytosolic Shigella in cage-like structures for targeting to autophagy. However, the factors mediating septin cage formation are mostly unknown. The Mostowy lab has recently - discovered that mitochondria are required for efficient septin cage assembly and that ~50% of entrapped Shigella are metabolically inactive. The precise fate of septin cage-entrapped bacterium (replication, persistence, death) remains to be defined. - For my project, called INCAGE, I will reconstitute the septin cage in vitro and study host and bacterial factors that modulate septin assembly. I will purify septin complexes and reconstitute septin assemblies (filaments, rings, cages) in vitro, and - investigate how auxiliary components (actin, mitochondria, endoplasmic reticulum) influence septin cage assembly. This will reveal how septins recognize bacteria and how they assemble into cage-like structures. In parallel, I will follow septin - cage-entrapped Shigella at the level of the single cell to study the lethal action of septin caging and uncover mechanisms that enable bacterial survival. I will test if the subpopulation of septin cage entrapped bacteria that stay alive, can - replicate or led to the formation of persister cells (transiently refractory to stress) able to cope with host imposed stress (antibiotics, autophagy). Completion of these objectives will identify factors that promote septin cage assembly and its - lethal action against entrapped bacteria. In depth understanding of septin cage assembly and its antibacterial activity can reveal important information about septin biology and cell-autonomous immunity, and help to design novel approaches to - counteract bacterial infections. - - 2019-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - INCAGE - - - H2020-MSCA-IF-2016 - - - 752022 - - - - - UMEA UNIVERSITET - - - EUR 185 857,20 - - - Unveiling the mitochondrial role of DNA2, a human helicase-nuclease causing mtDNA deletion associated syndrome. - - - EUR 185 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - Multiple deletions in mtDNA give rise to a variety of neuromuscular symptoms, often associated with genetic inherited disorders and aging and they have been reported in patients with neurodegenerative diseases, such as - Parkinson’s and Alzheimer’s diseases. In spite of its medical importance, not much is yet known about the mechanisms by which mtDNA deletions are formed. Progressive external ophtalmoplegia (PEO) is one of the conditions characterized by the - accumulation of mtDNA deletions. This disease is caused by mutations in components of the mtDNA replication machinery, like the DNA polymerase γ (POLγ) and the replicative helicase TWINKLE. Recently, also the helicase-nuclease DNA2 has been found - mutated in patients affected by this disorder. The precise function of human DNA2 (hDNA2) has remained elusive. hDNA2 localizes to mitochondria and has the biochemical properties to process four-stranded DNA structure (G-quadruplexes). Interestingly, - G-quadruplex DNA associates with mtDNA deletions formation in human diseases. - - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - MITOQUAD - - - H2020-MSCA-IF-2016 - - - 751474 - - - - - THE UNIVERSITY OF BIRMINGHAM - - - EUR 195 454,80 - - - Exploring Gender in Children's Literature from Cognitive Corpus Stylistic Perspective - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Gender equality remains a critical societal challenge. But how does one ‘learn’ gender? Children’s literature presents one early source of cultural norms, values and assumptions about gender. Language use in these texts is a - crucial means by which children learn about gendered concepts and behaviours. To understand this formative influence more deeply, the innovative GLARE project will examine the discursive construction of gender in corpora of English children’s - literature drawing on a novel cognitive corpus stylistic approach to characterization to conceptualise the notion of gender. GLARE will further take a diachronic perspective to the development of gender representation over time. The ‘cognitive corpus - stylistics’ links together corpus linguistics (CL) and Cognitive Poetics (CP). CL methods combine qualitative and quantitative approaches to text analysis while CP offers a theoretical framework to account for the creation of meaning in the mind of - the reader. The approach adopted by GLARE stresses that the representation of real and fictional people is related – in terms of the background knowledge that readers bring to texts and in terms of the patterns used in a text. Hence, relationships - between the representation of fictional characters and real people are to some extent a reflection of links between patterns in fictional and non-fictional texts. To investigate this relationship, the project draws on complementary data from the - Times Digital Archive. Through the description and analysis of linguistic patterns GLARE will provide novel insights into the way in which children’s literature can influence the creation of gendered concepts and behaviours. GLARE will be situated at - the University of Birmingham and supervised by Prof. Michaela Mahlberg, a world-leading expert in corpus stylistics. A secondment at Oxford University Press will allow the unique opportunity to access the largest electronic collection of children’s - books, the Oxford Children’s Corpus. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - GLARE - - - H2020-MSCA-IF-2016 - - - 749521 - - - - - FUNDACAO D. ANNA SOMMER CHAMPALIMAUD E DR. CARLOS MONTEZ CHAMPALIMAUD - - - EUR 148 635,60 - - - Impact of Neuromedin U in type 2 immunity and mucosal defence - - - EUR 148 635,60 - - - Portugal - - - Research Organisations - - Group 2 innate lymphoid cells (ILC2) are critical players in mucosal defense, tissue homeostasis and inflammation. ILC2 development and function have been widely perceived to be programmed. Nevertheless, how ILC2 perceive, - integrate and respond to environmental cues remains mostly unexplored. Here we hypothesize that ILC2 sense their environment and exert their function as part of a novel neuronal-ILC2 unit orchestrated by neuromedin U (NmU) signaling. - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Portugal - - - INIMUD - - - H2020-MSCA-IF-2016 - - - 750030 - - - - - TOSHIBA RESEARCH EUROPE LIMITED - - - EUR 183 454,80 - - - Development of an Ultra-Fast, Integrated, Certified Secure Quantum Random Number Generator for applications in Science and Information Technology - - - EUR 183 454,80 - - - United Kingdom - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The objective of this SE action is the development of an innovative quantum random number generator (Q-RNG). This device will represent an important shift forward in the current panorama of physical RNG. In fact, it will meet - simultaneously three requirements: being Ultra-Fast, Integrated, Certified Secure. The UFICS-QRNG will be developed with an SE action that will last 24 months. The researcher, that has matured a relevant expertise in the field of QRNGs, will join the - Quantum Information Group at the Toshiba Research Laboratories (TREL) based in Cambridge, UK. These laboratories are worldwide known for cutting edge research in Quantum Optics and Quantum Information. The project starting point will be a fast QRNG - prototype, recently developed by TREL. During the action, the researcher will develop a theoretical model to certify the randomness of the generator and will implement an integrated hardware. The UFICS-QRNG will be characterized by an unprecedented - level of security. Besides the theoretical model, which will account for all the side information sources that might weaken the generator unpredictability, the device will feature a self-testing protocol, for the continuous monitoring of the entropy. - The hardware will be designed to be compatible with other systems and the compliant with the standards. Security, generation rate at Gigabit/s and the possibility of integration in servers and computers, will make the UFICS-QRNG suitable for a - variety of applications in Science and Information Technology, which range from experiments of fundamental physics to simulation and cryptographic applications. In the latter case, the UFICS-QRNG will represent the best answer to the lack of physical - RNGs able to substitute the unsecure pseudo-RNGs. Given the peculiarity of TREL, an industrial institution that produces high impact scientific works, the researcher will benefit of a unique training, with the possibility to develop a professional - profile at the highest levels. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-SE - Society and Enterprise panel - - - United Kingdom - - - UFICS-QRNG - - - H2020-MSCA-IF-2016 - - - 750602 - - - - - PANEPISTIMIO KRITIS - - - EUR 152 653,20 - - - Florinated MOF for toxic gas capture - - - EUR 152 653,20 - - - Greece - - - Higher or Secondary Education Establishments - - Air pollution is both, an environmental and a social problem as it affects human health, ecosystems and play a key role in global warming. More than 80% of people are exposed to air quality levels that exceed safe limits, - being responsible for many premature deaths. European commission estimated to several billion euros the health-related cost due to air pollution. Some of the most important molecules accused by Europe, and so need to be reduce from atmosphere, are - nitrogen oxides, sulphure oxide, hydrogen sulfide and ammonia. In order to capture them from air, a convenient method is to use porous materials. Metal-Organic-Framework, a relatively new class of porous material, built up from polytopic linker and - inorganic node or clusters, already demonstrated excellent performance for gas capture. The tunability, at molecular level of these materials makes them serious candidates for separation applications. Recently, the applicant was part of the team who - designed a fluorinated MOF with a suitable pore and aperture size for selectively capturing propylene from propane , or capture CO2 from air at ppm level. This very robust material is opening the path of fluorinated hybrid material for toxic gas - separation and capture. This project aim to design, synthesis and characterize new single and mixed metal fluorinated MOFs in order to evaluated their capabilities for harmful gas capture. - - 2020-01-14, ongoing project - - - 2018-01-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Greece - - - FluMToGaC - - - H2020-MSCA-IF-2016 - - - 750533 - - - - - EUROPEAN MOLECULAR BIOLOGY LABORATORY - - - EUR 171 460,80 - - - Luminal pressure: a sculptor for mouse blastocyst self-organisation - - - EUR 171 460,80 - - - Germany - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - An important morphogenetic event of mammalian embryogenesis is the formation of a blastocyst with a fluid-filled cavity, blastocoel, and the establishment of three cell types essential for implantation. Morphogenesis of the - blastocyst begins with the emergence of multiple nascent cavities, which progressively coalesce to form one cavity segregating the cavity-facing primitive endoderm from the epiblast within the inner cell mass. While cell-to-cell gene expression - heterogeneity is well characterised during this lineage specification, little is known about the physical principles governing self-organized blastocyst morphogenesis and patterning. In particular, changes in fluid pressure, cell shape and polarity - during blastocyst formation remain uncharacterized. In this project, I will study the roles of fluid cavities in coordinating tissue mechanics, polarity and lineage specification. I will establish a novel micropressure technique to quantify the - growth of luminal pressure during blastocyst development. Combining micropipette aspiration with high-resolution live-embryo imaging, I will characterize the impact of fluid pressure on trophectoderm fate specification through dynamic changes in cell - shape and adhesion, and cytoskeletal remodeling. To assess the impact of fluid pressure on inner cell mass, I will study if cavity expansion induces apical polarisation and enhances primitive endoderm differentiation in cavity-facing cells. Combining - laser ablation with light-sheet microscopy, we will build a spatio-temporal map of intercellular forces in vivo during blastocyst development. We will further manipulate the cavity size to study if fluid pressure is functionally required and - sufficient for driving lineage segregation. This interdisciplinary and quantitative study will establish the novel role of fluid cavities and elucidate their interplay with biochemical signaling within the multi-cellular self-organization process. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - Fluidblasto - - - H2020-MSCA-IF-2016 - - - 748752 - - - - - TALLINNA TEHNIKAULIKOOL - BRANDENBURGISCHE TECHNISCHE UNIVERSITAT COTTBUS-SENFTENBERG - TECHNISCHE UNIVERSITEIT DELFT - POLITECNICO DI TORINO - CADENCE DESIGN SYSTEMS GMBH - IROC TECHNOLOGIES SA - INTRINSIC ID B.V. - IHP GMBH - INNOVATIONS FOR HIGH PERFORMANCE MICROELECTRONICS/LEIBNIZ-INSTITUT FUER INNOVATIVE MIKROELEKTRONIK - - - EUR 3 755 824,92 - - - Interdependent Challenges of Reliability, Security and Quality in Nanoelectronic Systems Design - - - EUR 3 755 824,92 - - - Estonia - Germany - Netherlands - Italy - Germany - France - Netherlands - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - - RESCUE ITN advances scientific competences and establishes an innovative training for Interdependent Challenges of Reliability, Security and Quality in Nanoelectronic Systems Design. - - 2021-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Estonia - - - RESCUE - - - H2020-MSCA-ITN-2016 - - - 722325 - - - - - VRIJE UNIVERSITEIT BRUSSEL - - - EUR 172 800 - - - How should automated profiling be regulated? - - - EUR 172 800 - - - Belgium - - - Higher or Secondary Education Establishments - - Profiling may threaten values that the law aims to protect, and undermine goals that the law aims to achieve. Profiling involves automated processing of personal or other data to develop profiles that can be used to make - decisions about people. Profiling can be used in different contexts. For instance, (i) with retail price discrimination, online shops charge different consumers different prices for the same or similar products. (ii) Lenders use profiling to estimate - a consumer’s creditworthiness. Lenders can adapt interest rates to certain consumers, or refuse to lend to them. (iii) Predictive policing refers to the use of profiling technology to predict criminal behaviour.However, profiling has drawbacks. For - instance, profiling can discriminate unintentionally, when an algorithm learns from data reflecting biased human decisions. Additionally, profiling is opaque: people may not know why they are treated differently. Making profiling transparent is - difficult, among other reasons because of the complexity and the possibly ever-changing nature of algorithms. - - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Belgium - - - PROFILE - - - H2020-MSCA-IF-2016 - - - 748514 - - - - - EUROPEAN MOLECULAR BIOLOGY LABORATORY - - - EUR 159 460,80 - - - In Situ structural Analysis of Nuclear Pore Complex ASsembly Intermediates by cryo-FIB-tomography - - - EUR 159 460,80 - - - Germany - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Nuclear pore complexes (NPCs) are fundamental supra-molecular complexes mediating the molecular traffic between nucleus and cytoplasm. They consist of over 1000 proteins that need to be assembled in a coordinated manner each - cell division. Recent structural work has elucidated a considerable part of the NPC architecture, however how the NPC scaffold is assembled remains poorly understood on the structural and mechanistic level. - - - 2020-08-31, Grant Agreement terminated - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - ISA-NPC-ASI - - - H2020-MSCA-IF-2016 - - - 745988 - - - - - UNIVERSITY COLLEGE LONDON - - - EUR 183 454,80 - - - The role of novel opsins in non-visual light detection in the zebrafish brain - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Light impacts on life by modulating the physiology and behaviour of most living organisms. Both vertebrates and invertebrates have developed an extensive and diverse range of photoreceptor structures and photopigments, which - mediate these light responses. Clearly light is used for vision, being detected by specialized rod and cone cells in the retina and processed by the visual centers of the brain. However, light also regulates many non-visual processes, and novel - nonvisual photopigments are regularly being discovered. Recent studies have shown a role for non-visual photoreception in seasonal responses, activation of DNA repair mechanisms, entrainment of the circadian clock and sleep-wake regulation, but the - mechanisms are far less understood. This phenomenon is particularly extensive in teleosts such as zebrafish, where all tissues and cells of the adult and larval body are directly light responsive. The purpose of ZNEOPSIN_II is to determine the role - that non-visual light detection plays in early development in zebrafish, focusing on neurobiology, the entrainment of the circadian clock and specific aspects of behaviour. I will take advantage of zebrafish, a genetic model organism available at the - host lab, a leading zebrafish circadian biology lab at University College London, which is also one of the larger zebrafish research communities in Europe. The latest technical approaches for gene knockdown (CRISPR/Cas genome editing), and - luminescent/fluorescent imaging, together with classical molecular biology techniques, will be combined with state of the art behavioural assays developed in zebrafish. The results of ZNEOPSIN_II will provide invaluable insights into the biological - significance of non-visual light detection, and the roles played by a range of newly discovered opsins, as well as provide a junior researcher with the best possible training in both molecular biology, functional neurobiology and behaviour. - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ZNEOPSIN_II - - - H2020-MSCA-IF-2016 - - - 749990 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 185 076 - - - The evolutionary history of oncogenic and non-oncogenic papillomaviruses - - - EUR 185 076 - - - France - - - Research Organisations - - Certain papillomaviruses (PVs) are a major public health concern as in humans they are responsible for virtually all cases of cervical and anal cancer, and for a fraction of cancers on the penis, vagina, vulva and oropharynx. - But oncogenic PVs are actually an unfortunate exception, as most PVs cause asymptomatic infections, and a few cause benign, wart-like lesions. Despite the efforts directed towards the understanding of the different clinical manifestations of - infection, our knowledge on PV evolution remains fragmentary. - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - ONCOGENEVOL - - - H2020-MSCA-IF-2016 - - - 750180 - - - - - ROYAL COLLEGE OF SURGEONS IN IRELAND - - - EUR 175 866 - - - The ATP-P2X7R axis: a target for drug-refractory epilepsy - - - EUR 175 866 - - - Ireland - - - Higher or Secondary Education Establishments - - Current epilepsy therapies, based on mediating excitation or inhibition have no impact on disease progression and are ineffective in over 30% of patients, demonstrating the urgent need for therapies with different mechanisms - of action. An exciting concept is that increased hyperexcitability states and network changes are caused and maintained by a sustained glial activation.The ATP-gated P2X7 receptor (P2X7R), a gatekeeper of inflammation, has recently emerged as a - promising target for epilepsy, showing anticonvulsant and disease-modifying properties in animal models. To bring P2X7R further towards a clinical application, however, important gaps in our understanding must be filled. Evidence for ATP release in - the brain during seizures is currently lacking, the cell types involved in pathological P2X7R activation must be determined, and whether results from rodent models can be replicated in human tissue must be tested. Recent technical advances now bring - the answers to these questions within reach. EpiPur brings together a team of experts in purinergic signalling, industrial partners specialised in the development of P2X7R antagonists and epilepsy clinicians. Biosensors will be used to record ATP in - vivo with high sensitivity and temporal resolution; new transgenic mouse lines will be used to elucidate the subcellular expression and cell-specific disease contribution of P2X7R. Newly developed P2X7R antagonists will be tested in brain tissue - resected from epilepsy patients. This highly interdisciplinary and intersectoral approach will add a significant contribution to the understanding of neuroinflammatory processes in disorders of the CNS. Further, the skills acquired during the - research project, the excellent training record of the supervisor and host institution and the outstanding resources for learning and development available at RCSI will give me the tools necessary to achieve research independence. - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Ireland - - - EpiPur - - - H2020-MSCA-IF-2016 - - - 753527 - - - - - UNIVERSITE PARIS DESCARTES - - - EUR 173 076 - - - HEpatocellular carcinoma GErmline MutatiONs ImpaCt (HEGEMONIC) - - - EUR 173 076 - - - France - - - Higher or Secondary Education Establishments - - Hepatocellular carcinoma (HCC) is the second most common cause of cancer death worldwide. Although several environmental factors have been identified, many affected individuals never develop HCC, suggesting a genetic - susceptibility. Candidate genes and genome-wide association studies (GWAS) have only uncovered a few variants reproducibly linked to HCC. GWAS design typically allows the detection of common variants that usually have small effect sizes. Even taken - together, they explain a very limited proportion of the heritability. This could reflect the presence of rare variants that may confer very large effect sizes. These may be captured by next-generation sequencing (NGS). Whole exome sequencing (WES) of - thousands of tumors has defined the somatic genetic landscape of the most common cancers. Using WES, the host group has strongly contributed to the identification of the major pathways recurrently mutated in HCC. Nevertheless, despite the large - amount of NGS data generated by cancer genome projects, the analysis of rare germline variants (i.e. variation pre-existing in normal cells) is currently a neglected field, particularly in liver carcinogenesis. The HEGEMONIC project hypothesizes that - rare variants in coding regions of the genome (exome) impact the risk of HCC. This project proposes an integrative approach combining (epi)genomic information generated by the host group and from publicly available sources. First, the applicant will - compare WES data from a series of 350 patients with HCC to nearly 70,000 controls compiled by the Exome Aggregation and UK10K consortia. Then, validation of the top signals will be performed by conventional sequencing in three replication cohorts. - Finally, the applicant will analyze genotype-phenotype associations, taking advantage of the extensive clinical data available. Ultimately, the HEGEMONIC project may generate new biological hypotheses in liver carcinogenesis and identify new - biomarkers and pharmaceutical targets. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - HEGEMONIC - - - H2020-MSCA-IF-2016 - - - 748604 - - - - - FUNDACIO INSTITUT CATALA DE NANOCIENCIA I NANOTECNOLOGIA - - - EUR 158 121,60 - - - FLEXOELECTRIC SCAFFOLDS FOR BONE TISSUE ENGINEERING - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - "Bone is the most transplanted tissue with 1.3 million procedures every year in Europe. With an increasing demographic ageing across Europe, bone transplant represents a significant socio-economic burden that necessitates new - bone regeneration strategies in line with one of the Horizon 2020 priority: ""Smart Growth: knowledge and innovation based economy"". The field of bone tissue engineering has flourished over the last decades, owing to a solid knowledge on bone - biology and increased progress on materials engineering. A few weeks ago, Dr Gustau Catalan at ICN2 brought to light the groundbreaking discovery that bone is flexoelectric. In order to biomimic the flexoelectric character of bone, we aim in this - project to produce new synthetic bone scaffolds that exhibit flexoelectricity. Engineering scaffolds with a flexoelectric character calls for particular design requirements. Flexoelectricity is the coupling between strain gradients and polarization, - whereby any dielectric can polarize in response to an inhomogeneous deformation. In order to generate the required strain gradients within the scaffold to produce a flexoelectric effect, scaffolds will be manufactured with controlled porosity - gradients by 3D printing based approaches. Three polymers used in bone tissue engineering, namely PLLA, PLGA and PCL will be investigated to produce the flexoelectric scaffolds. It is envisaged that a flexoelectric-induced polarization can be - attained in any of them. In view of improving the osteoconductive, osteogenic and mechanical properties of the flexoelectric scaffolds, they will further incorporate different amounts of nanohydroxyapatite (from 0 to 50 wt %). Finite element - calculations will be used to refine porosity geometries (porosity gradient and pore shape). It is expected that through careful geometrical design of porosity, scaffolds could exhibit a bone-like flexoelectric effect that would not only support the - bone tissue regeneration process but also stimulate it." - - 2019-09-14, ongoing project - - - 2017-09-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - FLEXOBONEGRAFT - - - H2020-MSCA-IF-2016 - - - 753186 - - - - - HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH - - - EUR 159 460,80 - - - Exploring the cellular heterogeneity underlying 'tumor-educated' platelets - - - EUR 159 460,80 - - - Germany - - - Research Organisations - - Cancer is one of the major causes of death worldwide. Early detection leads to treatment initiation in earlier cancer stages and therefore increases the chance of survival. However, appropriate diagnosis can be challenging - because tissue acquisition of tumor samples for molecular testing often requires invasive procedure. To overcome these challenges researchers have focused on the real-time monitoring of molecules and cells in easily obtainable peripheral blood to - gain diagnostic information, termed 'liquid biopsies'. A recent study by Best et al profiled purified platelet gene expression from cancer patients and healthy controls and was able to predict disease status and location of the primary tumor with 96% - and 71% accuracy, respectively using a machine learning based algorithm. The pan-cancer nature of their finding is a major advancement compared to other liquid biopsy approaches and highlights the utility of platelets as an all-in-one platform for - blood-based cancer diagnostics. We plan to advance the idea of platelet liquid biopsies by studying platelet single-cell RNA sequencing data from cancer patients and healthy controls. The overall goal of the proposed project is to investigate single - platelet gene expression to gain insight into the molecular mechanisms underlying tumor driven changes in the platelet RNA profile. - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Germany - - - PlateletLiquidBiopsy - - - H2020-MSCA-IF-2016 - - - 753039 - - - - - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - - - EUR 183 454,80 - - - Multi-level Model Calibration for the Assessment of Historical Masonry Structures - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The MultiCAMS project will develop an advanced computational strategy including numerical modelling and innovative model calibration for realistic assessment of historical unreinforced masonry structures. The presence of - relevant historical heritage in Europe, partly still in use, together with high seismic risk in the Mediterranean areas highlights the need of assessing such structures considering current safety requirements and if necessary strengthened to prevent - critical failure. The proposed assessment approach is based on the use of models with different levels of sophistication, comprising detailed mesoscale models where masonry units and mortar joints are modelled separately (low level), homogeneous - shell/solid-element models in which masonry is considered as a continuum (intermediate level), and efficient macroscale models where entire structural parts (i.e. piers, spandrels) are represented by appropriate macro-elements (high level). In this - respect, I will develop a novel numerical description with macro-elements for an efficient and practical analysis of masonry structures accounting for the interaction between the nonlinear in-plane and out-of-plane behaviour of different URM - components. An innovative model calibration strategy utilising inverse analysis techniques will thus be developed to couple the efficiency of the novel simplified mechanical model and the accuracy of existing detailed models, such as the parameters - of each model will be determined from the inverse analysis of the numerical response of the lower-level model. The main outcome of MultiCAMS will be a comprehensive and accurate methodology for the seismic assessment of historical masonry buildings, - which represents an urgent requirement for the safeguard of human lives in many European urban areas, as shown by recent catastrophic events. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - MultiCAMS - - - H2020-MSCA-IF-2016 - - - 744400 - - - - - ITA-SUOMEN YLIOPISTO - - - EUR 1 255 680 - - - Genomics and Mechanisms in Translational Medicine Doctoral Programme - - - EUR 2 511 360 - - - Finland - - - Higher or Secondary Education Establishments - - The GenomMed programme will train international experts who are wanted in the European job market and future research leaders in translational genomics. These experts aim to solve health care -related questions in - cardiovascular and metabolic diseases and neurosciences. They will have skills to create solutions and innovations to develop novel treatments in the European and global environment. Health care is globally faced with a growing burden of major - age-associated diseases. New means of diagnosis and treatment are needed to survive the challenges. - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2016 - Co-funding of regional, national and international programmes - - - MSCA-COFUND-DP - Doctoral programmes - - - Finland - - - GenomMed - - - H2020-MSCA-COFUND-2016 - - - 740264 - - - - - KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW - - - EUR 177 598,80 - - - A neuroscience approach to investigating how hierarchy influences moral behaviour - - - EUR 177 598,80 - - - Netherlands - - - Research Organisations - - Humans are very social animals who are able to understand the consequences of their actions on others. Therefore, why is it that some individuals are more likely to choose actions that have negative consequences for others? - This project will explore this important question by using an original and innovative approach focusing on the subjective experience of agency and responsibility of individuals when they select a moral or an immoral action, together with their - empathic response at the moment of the act. The general aim of the present research project is to refine our understanding of the mechanisms driving both responsibility and empathy and to generate a model that integrates these two aspects to better - understand what guides moral behaviours in coercive situations. To achieve this aim, we will use psychophysiology and fMRI techniques to understand how the neural circuits associated with the sense of agency and empathy interact through different - experimental paradigms. This project will shed new light on how our self-experience impacts on our moral decisions. In addition to opening new perspectives in social neuroscience and psychology, this project will add theoretical and methodological - expertise to my skill-set by providing the most suitable environment, that is, the Social Brain Lab at the Netherlands Institute for Neuroscience (NIN), for my career development. The NIN will offer: (i) world experts in human empathy with prominent - expertise in fMRI and EEG techniques (C. Keysers and V. Gazzola); (ii) all the technical facilities necessary for the success of the present research project, and (iii) a world leading neuroscience community that will contribute to my further - training and career prospects. - - 2019-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - AGENT - - - H2020-MSCA-IF-2016 - - - 743685 - - - - - JOHANNES GUTENBERG-UNIVERSITAT MAINZ - - - EUR 159 460,80 - - - Fast electronics with Antiferromagnetic SpinTronics - - - EUR 159 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - The end of scaling according to Moore’s law will reinforce the need to look for energy efficient and faster devices based on alternative materials and concepts that are however compatible with Complementary - metal-oxide-semiconductor (CMOS). A new generation of logic and storage devices might arise from promising antiferromagnetic materials because of the absence of a net magnetic moment and of the characteristic frequencies of THz-order. In an - antiferromagnet, the electron spins on adjacent atoms cancel each other out. An antiferromagnet has thus no associated magnetic field meaning that individual devices can encode information and be packed ultimately densely without interacting with one - another. Simultaneously, the origin of this stability makes the antiferromagnet state difficult to read and control. The recent combination of antiferromagnets and spintronics has however opened the road towards the electrical control of their - magnetic order. - - - 2019-07-14, ongoing project - - - 2017-07-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - FAST - - - H2020-MSCA-IF-2016 - - - 752195 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 158 121,60 - - - Cdon-Hh Interaction: functional in vivo analysis in zebrafish - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - Patterning of the vertebrate optic vesicle into proximal/optic stalk and distal/neural retina involves midline-derived Hh signalling, which promotes stalk specification. At the neural retina/optic stalk border, the cell - adhesion molecule Cdon binds Hh, acting as a decoy receptor to protect the neural retina from Hh activity. How Cdon controls Hh dispersion, what is the destiny of the Hh protein accumulated at the neural retina/optic stalk boundary, whether Cdon - participates in the release of Hh from its producing cells or whether Cdon has Hh-unrelated functions in the neural retina are the arising and still unanswered questions I aim to tackle in this proposal. Using the zebrafish as a model system and - CRISPR/Cas9 technology I will first generate unprecedented tools to follow in vivo Cdon/Hh interaction, and then address how Cdon, expressed in both the ventral diencephalic midline and the neural retina, shapes the gradient of Hh responsible for - proximo-distal patterning of the eye. I expect that the development of this proposal will provide significant advance on how morphogenetic signalling pathways operate, ultimately reverting into the field of regenerative medicine and clinical research - related to congenital ocular malformations. - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - CHI-ZEF - - - H2020-MSCA-IF-2016 - - - 740916 - - - - - FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION - - - EUR 187 419,60 - - - The trade-off between longevity and reproduction: optimal control of aging - - - EUR 187 419,60 - - - Switzerland - - - Research Organisations - - The lifespan of genetically identical organisms varies depending on the environment they are exposed to. A well-known example is the extension of lifespan by nutrient restriction, as observed in animals as diverse as nematodes - and rhesus monkeys. Why does the lifespan of animals change with environmental conditions? Is there an advantage to living longer when food is poor, and to living shorter when food is plentiful? - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - OPTiAGE - - - H2020-MSCA-IF-2016 - - - 751878 - - - - - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - - - EUR 185 076 - - - The neural correlates of the self in altered states of consciousness. - - - EUR 185 076 - - - France - - - Research Organisations - - The consciousness of self is fundamental to our human existence. In several mental health afflictions there appears to be a change in the relation between the self and conscious experience: in anxiety and depression, people - can be absorbed in negative thoughts, while in (traumatic) dissociation, distance between the self and conscious experience can occur. Studies report that meditation and hypnosis can help alleviate symptoms of anxiety, depression and post-traumatic - stress, but it is unclear why. I hypothesise that meditation and hypnosis change the relation between the self and the conscious experience. I aim to study the neural correlates of these changes in self-consciousness during meditative and hypnotic - states with functional Magnetic Resonance Imaging in healthy controls and intracranial electroencephalography in people with epilepsy, which is the only way to directly measure the activity of deep brain structures thought to play a role in - self-consciousness, such as the insula. I will combine these measurements with first-person interviews and behavioural tasks. This innovative study will elucidate the neural correlates of the consciousness of self and will help understand the - reported beneficial effects of meditation and hypnosis on mental health. - - 2019-06-20, ongoing project - - - 2017-06-21 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - NeuCoSe - - - H2020-MSCA-IF-2016 - - - 749582 - - - - - CARDIFF UNIVERSITY - - - EUR 195 454,80 - - - Innovation in Investigative Journalism - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The objective of SCOOP is to study the impact of innovative technologies and new funding mechanisms on the role and working practices on investigative journalism. Investigative journalism should play a key role in democracy, - but developments in digital media and new technologies (drones, mobile cameras) and changing funding models (crowd sourcing) is transforming this. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SCOOP - - - H2020-MSCA-IF-2016 - - - 746899 - - - - - KING'S COLLEGE LONDON - - - EUR 183 454,80 - - - Functional impact of alternative splicing coupled to nonsense-mediated decay in developing neurons - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Differentiation of precursor cells into mature neurons relies on transcriptome-wide changes in gene expression that have to be coordinated in a precise spatiotemporal fashion. Alternative pre-mRNA splicing coupled to - nonsense-mediated decay (AS-NMD) is a widespread post-transcriptional mechanism known to orchestrate gene expression dynamics in developmental contexts. Earlier studies identified several neural targets of this pathway; however, in most cases, the - extent to which AS-NMD contributes to the overall gene expression dynamics and biological significance of this regulation is poorly understood. Moreover, whether AS-NMD target repertoire undergoes considerable changes in developing brain and how this - might fit to the global regulation network underlying neuronal differentiation remains unclear. I will address these questions using two separate approaches. First, I will investigate novel AS-NMD targets encoding actin cytoskeleton factors and - controlled by an important regulator of neuronal alternative splicing, Ptbp1. I will elucidate the extent of AS-NMD regulation in these genes by modulating the inclusion of the NMD-promoting exons with corresponding antisense oligonucleotides. in - mouse embryonic stem cells undergoing neuronal differentiation, neural stem cells and primary neurons. Second, I will systematically analyse how NMD contributes to different stages of neuronal development by acutely inhibiting this pathway in a - time-resolved manner using genetic means. I will then identify gene expression effects and functional consequences of NMD inactivation using transcriptome sequencing (RNA-Seq) and appropriate cell biological methods. All in all, this work will - provide critical quantitative insights into AS-NMD functions and uncover novel mechanisms allowing neurons to attain their unique morphological and functional properties. - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - NEURO_NMD - - - H2020-MSCA-IF-2016 - - - 751739 - - - - - UNIVERSITAET LEIPZIG - - - EUR 171 460,80 - - - Perception of Eastern Religions in Europe - - - EUR 171 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - The issues of globalisation, intercultural relations, migration crisis and ecological crisis are among the most challenging problems that Europe is currently facing. In their core lies the issue of identity-otherness dual. The - present project attempts to address these problems in an innovative way seeking to understand whether the current situation in Europe leads to transformation of the dominant European worldview and whether and how Eastern religions influence this - process. Therefore, the aim of the project is to investigate the contemporary interrelation between Europe and Eastern religions. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - GINGER - - - H2020-MSCA-IF-2016 - - - 753561 - - - - - UNIVERSITE LIBRE DE BRUXELLES - - - EUR 172 800 - - - Brain-speech tracking in noisy conditions: towards the identification and remediation of dyslexia. - - - EUR 172 800 - - - Belgium - - - Higher or Secondary Education Establishments - - Dyslexia is a developmental disorder leading to reading difficulties. It affects 5–12 % of children and young adults. Unfortunately, we still lack efficient and cost effective methods to identify and remedy this disorder. - Dyslexia appears to be frequently linked to hindered phonological processing at the cortical level, with drastic consequences in the presence of noise. The overarching goal of this project is to better understand cortical speech processing in the - presence of noise, in order to provide novel identification and remediation methods for dyslexia. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Belgium - - - DysTrack - - - H2020-MSCA-IF-2016 - - - 743562 - - - - - FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION - - - EUR 187 419,60 - - - Muscle Specific C. elegans Genome in health and disease: finding novel factors in 3D organization - - - EUR 187 419,60 - - - Switzerland - - - Research Organisations - - The loss of structural integrity in the interphase nucleus leads to tissue-specific pathologies in a set of human diseases collectively called laminopathies. These are late-onset, tissue-specific degenerative diseases, such as - Emery Dreifuss Muscular Dystrophy (EDMD). While rare, these conditions provide insight into more common degenerative disorders linked to aging. A Caennorhabditis elegans mutant that recreates the EDMD phenotypes arises from introduction of a specific - gain-of-function mutation into lamin (LMN-1 Y59C), which in turn affects the subnuclear distribution of muscle-specific promoters. This proposal plans to identify novel factors that establish and/or maintain the 3D organization of the genome in - differentiated nuclei and to determine how this contributes to the differentiated muscle cell fate. I propose that compromised or altered sequestration of chromatin at the nuclear envelope alters cell-type specific promoter induction and in turn - compromises the integrity of the tissue in question. - - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - MuSCel Genome - - - H2020-MSCA-IF-2016 - - - 750114 - - - - - TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY - - - EUR 170 509,20 - - - New Material Hybrids With Helical Inner Architecture: Fundamentals And Technology - - - EUR 170 509,20 - - - Israel - - - Higher or Secondary Education Establishments - - A new approach to design and manufacture hybrid materials based on biomimetic principles is proposed. The internal structure of multi-component metal hybrids will be created simultaneously at two levels: nanostructuring each - constituent while also architecturing helical macroscale features. - - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Israel - - - HybridMat - - - H2020-MSCA-IF-2016 - - - 742098 - - - - - FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION - - - EUR 187 419,60 - - - Genomic binding of transcription factors as a function of DNA affinity and chromatin. - - - EUR 187 419,60 - - - Switzerland - - - Research Organisations - - Transcription factors (TFs) read cis-regulatory information encoded in the genome and by doing so, they establish gene expression patterns. However, TFs must compete with structural chromatin proteins such as nucleosomes for - access to DNA, and this may partially explain why only a fraction of their sequence motifs in the genome are actually bound. It is unclear what features discriminate used from unused sites with similar motifs, in vivo, though it is likely that - sensitivity of TFs to chromatin is critical for normal gene expression. For example, some TFs have reduced chromatin sensitivity, termed pioneer-factors, and are able to drive differentiation; even these bind a minority of cognate motifs in the - genome. Such factors may nevertheless modify chromatin and expose motifs for TFs with higher sensitivity. Alternatively, chromatin proteins and modifications may be intrinsically directed by unidentified DNA sequence features. Though little is known - about determines of TF-chromatin sensitivity, it is likely a function of DNA affinity and the ability to recruit chromatin-modifying activity. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - TF-bind Determinants - - - H2020-MSCA-IF-2016 - - - 748760 - - - - - FUNDACION IMDEA ALIMENTACION - - - EUR 257 191,20 - - - Small open reading frames (smORF) as novel modulators of disorders of dietary excess - - - EUR 257 191,20 - - - Spain - - - Research Organisations - - Dietary excess is the major origin of cardiovascular diseases and remains the leading cause of mortality. Due to difficulties with bioinformatics detection and experimental analysis, along with their sheer numbers, small open - reading frames (smORF) –of fewer than 100 amino acids– have been largely disregarded. Advances in bioinformatics, RNA-sequencing (ribosome profiling), biochemical (peptidomics) and functional (genetic) screens, suggest that a large amount of smORF - are transcribed and sometimes widely conserved. However, how much of these smORF-encoded peptides or small proteins (microproteins (MPs)) are translated into a functional peptide is largely unknown. Moreover, whether food bioactive components - modulate the expression of MPs remains complete obscure. Thus, the main goal of this project is to search for MPs that regulate lipid metabolism in the intestine in response to dietary excess. The intellectual merits of this proposal are threefold. - First, it will use cutting-edge technology to search for novel functional MPs. Second, it will address a new group of novel potential players not previously addressed in lipid metabolism, providing a novel insight into disease mechanism and - innovative therapeutic strategies. Last, by testing two common food bioactive components from our healthy Mediterranean diet, we will open up a completely new field of research in the area of nutrition and health. The research approach will involve - (i) a genome-wide peptidomic screen and ribosome profiling analysis of lipid-induced intestinal MPs, (ii) the use of in vivo and in vitro biochemical approximations to validate the function of the selected intestinal peptide, and (iii) the use of - dietary components hydroxytyrosol and the omega-3 polyunsaturated fatty acid DHA as proof of concept that MPs can be modulated by our diet food bioactive. This project is framed in the “Food & Healthy Diet and Biotechnology” research area in the - European Union's Framework Programme HORIZON 2020 - - 2020-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Spain - - - LIPMETIN-sURFing - - - H2020-MSCA-IF-2016 - - - 746435 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 185 076 - - - Investigating the structural role of the Hepatitis B virus core proteinC-terminal domain in assembly and maturation using solid-stateNMR - - - EUR 185 076 - - - France - - - Research Organisations - - We will seek in this project to reveal structural and dynamic features of the C-terminal domain (CTD) of the Hepatitis B virus (HBV) core protein which encapsidates the viral genome. Each year, over 750,000 deaths are due to - serious liver diseases caused by chronic HBV infection. Hepatitis B is, despite the availability of a vaccine, still a major health problem. The HBV virus particle is composed of an outer lipid-protein envelope and a core protein of 20 kDa that - self-assembles into icosahedral nucleocapsids. The nucleocapsid encloses the pregenomic RNA (pgRNA) that is then reverse-transcribed into DNA by the viral polymerase (Pol). During pgRNA encapsidation, the CTD is thought to interact with the RNA. - Despite the essential role played by the CTD in the regulation of the viral life cycle through various conformational states and phosphorylation patterns, it escapes today to classical structural biology approaches due to its dynamic nature. We will - use solid-state NMR to bring new insights into the precise conformation and localization of the CTD along various steps of the viral life cycle. Sample preparation protocols of the core protein have recently been established by the applicant in the - host laboratory using bacterial expression systems. The first NMR spectra of the nucleocapsid look highly promising. Further experiments will be recorded to assign the resonances and identify the CTD signals. Different phosphorylation states and - binding partners, as the pgRNA, will be explored. Finally, paramagnetic tags will be used to obtain information about the positioning of the CTD. - - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - HBVssNMR - - - H2020-MSCA-IF-2016 - - - 748516 - - - - - UNIVERSITY OF LEEDS - - - EUR 195 454,80 - - - How insulin resistance in the dorsal vagal complex affects glucose metabolism and feeding behaviour - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The central nervous system (CNS) integrates peripheral hormonal signals to regulate glucose homeostasis and feeding behavior. Obesity can cause the development of insulin resistance in the brain and completely disrupt the - regulative functions of the CNS. Restoring the brain’s ability to modulate metabolic functions could be very important to prevent the negative outcomes of obesity and diabetes. The Dorsal Vagal Complex (DVC) in the brainstem senses insulin to - regulate glucose metabolism and feeding behavior in rodents. Three days of high fat diet feeding (HFD) is sufficient to completely disrupt the insulin response, thus causing an increase in blood glucose levels and overnutrition. I propose to - understand the molecular events that trigger the development of insulin resistance in the DVC and understand the neuronal networks involved in the regulation glucose metabolism and feeding behavior in the DVC. I will use a combination of in vitro - molecular approaches and in vivo physiological readouts to shed light on the physiological functions of this area of the brain. Identification of novel target molecules that are involved in the development of insulin resistance may also provide the - basis for the development of new pharmacological approaches to counteract the development of obesity and diabetes. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - United Kingdom - - - CNS-Insuin-Res - - - H2020-MSCA-IF-2016 - - - 752408 - - - - - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - - - EUR 152 653,20 - - - The origin of the Galactic magnetic field - - - EUR 152 653,20 - - - Greece - - - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - - Magnetic fields lie at the heart of essentially all the outstanding problems in galactic evolution. However, the measurement of interstellar magnetic fields is very challenging. We can either measure the strength or the - direction of the magnetic field vector in different regions of the Milky Way. Clearly, in order to assess the impact of the magnetic field in the core processes of galactic evolution, such as star formation and stellar feedback, we need to complement - the observations with simulations of the magnetic field evolution. - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Greece - - - ORIGAMI - - - H2020-MSCA-IF-2016 - - - 749073 - - - - - FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION - - - EUR 175 419,60 - - - Understanding long-range transcriptional regulation in the context of the 3D genome organization - - - EUR 175 419,60 - - - Switzerland - - - Research Organisations - - Enhancers are regulatory elements that control the spatial and temporal expression of genes in metazoans. Enhancers are able to modulate transcription of a target gene from large genomic distances, as a result of the formation - of chromatin loops that bring them in close spatial proximity to cognate promoters. The manner how specific patterns of enhancer-promoter physical interactions are established is linked to how chromosomes are folded in the three-dimensional (3D) - space. Recent studies based on chromosome conformation capture (3C) have shown that mammalian chromosomes are partitioned into self-associating sub-megabase domains called Topologically Associating Domains (TADs). Genetic evidence suggests that 3D - chromatin organization within and across TADs contributes to the establishment and partitioning of enhancers-promoters physical communication. Yet it is still unknown by which biophysical mechanisms chromosome architecture modulates enhancer action, - and thus transcription. The goal of this proposal is to determine the quantitative relationship between 3D chromatin architecture and enhancer-promoter activity to unravel the mechanism of long-range transcriptional modulation mediated by enhancers. - Addressing this goal requires a system where transcriptional outputs can be measured precisely and quantitatively, and correlated with 3D distances. To this aim, we will use state-of-the art genome engineering techniques to generate mouse embryonic - stem cells with engineered enhancer-promoter pairs in an isolated chromatin environment, where a selected enhancer can be mobilized at different distances from its cognate promoter. We will use this system to quantitatively assess how 3D chromatin - structure influences enhancer action by measuring transcription and promoter-enhancer interactions using 3C-based technologies, single-cell methods and live-cell imaging. This will lead to an unprecedented view of the mechanisms underlying long-range - transcriptional regulation. - - 2019-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - 3DQuant - - - H2020-MSCA-IF-2016 - - - 748091 - - - - - RIJKSUNIVERSITEIT GRONINGEN - - - EUR 165 598,80 - - - Microscopic modelling of the highly efficient intra- and inter-antennae energy transfer to the reaction centre in plant photosystem II - - - EUR 165 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - MicroMod-PSII aims to provide an unprecedented microscopic, structure-based understanding of the excitation energy transfer mechanism in plant photosystem II (PSII) from the outer antennae complexes to the reaction centre - under physiological conditions. It will unravel nature’s highly sophisticated way of harvesting sunlight in unrivalled detail. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - MicroMod-PSII - - - H2020-MSCA-IF-2016 - - - 748895 - - - - - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - UNIVERSITY OF CYPRUS - FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. - SIGNALGENERIX LTD - UNIVERSITAT POLITECNICA DE CATALUNYA - AALTO-KORKEAKOULUSAATIO - - - EUR 5 748 000 - - - VisorSurf - A Hardware Platform for Software-driven Functional Metasurfaces - - - EUR 5 748 000 - - - Greece - Cyprus - Germany - Cyprus - Spain - Finland - - - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Metasurfaces, thin film planar, artificial structures, have recently enabled the realization of novel electromagnetic (EM) and optical components with engineered functionalities. These include total EM radiation absorption, - filtering and steering of light and sound, as well as nano-antennas for sensors and implantable devices. Nonetheless, metasurfaces are presently non-adaptive and non-reusable, restricting their applicability to a single, static functionality per - structure (e.g., steering light towards a fixed direction). Moreover, designing a metasurface remains a task for specialized researchers, limiting their accessibility from the broad engineering field. VISORSURF proposes a hardware platform-the - HyperSurface-that can host metasurface functionalities described in software. The HyperSurface essentially merges existing metasurfaces with nanonetworks, acting as a reconfigurable metasurface whose properties can be changed via a software - interface. This control is achieved by a network of miniaturized controllers, incorporated into the structure of the metasurface. The controllers receive programmatic directives and perform simple alterations on the metasurface structure, adjusting - its EM behavior. The required end-functionality is described in well-defined, reusable software modules, adding the potential for hosting multiple functionalities concurrently and adaptively. VISORSURF will study in depth the novel and unexplored - theoretical capabilities of the HyperSurface concept. Two experimental prototypes will be implemented: a switch-based fabric array as the control medium; and a Graphene based, making use of its exquisite properties to provide finer control. A real - pilot-application will demonstrate the HyperSurface potential to adapt to changes in their environment, to interconnect to smart control loops and make use of Information Technology (IT) programming concepts and algorithms in crafting the EM behavior - of materials. - - 2020-06-30, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-01-2016-2017 - FET-Open research and innovation actions - - - RIA - Research and Innovation action - - - Greece - - - VISORSURF - - - H2020-FETOPEN-1-2016-2017 - - - 736876 - - - - - UNIVERSITA DEGLI STUDI DI PERUGIA - UNIVERSITA DEGLI STUDI DI PERUGIA - - - EUR 1 883 749,68 - - - Dissecting to hit the therapeutic targets in nucleophosmin (NPM1)-mutated acute myeloid leukemia - - - EUR 1 883 749,68 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Acute myeloid leukemia (AML) is a group of hematologic malignancies which, due to their molecular and clinical heterogeneity, have been traditionally difficult to classify and treat. Recently, next-generation, whole-genome - sequencing has uncovered several recurrent somatic mutations that better define the landscape of AML genomics. Despite these advances in deciphering AML molecular subsets, there have been no concurrent improvements in AML therapy which still relies - on the ‘antracycline+cytarabine’ scheme. Hereto, only about 40-50% of adult young patients are cured whilst most of the elderly succumb to their disease. Therefore, new therapeutic approaches which would take advantage of the new discoveries are - clearly needed. In the past years, we discovered and characterized nucleophosmin (NPM1) mutations as the most frequent genetic alteration (about 30%) in AML, and today NPM1-mutated AML is a new entity in the WHO classification of myeloid neoplasms. - However, mechanisms of leukemogenesis and a specific therapy for this leukemia are missing. Here, I aim to unravel the complex network of molecular interactions that take place in this distinct genetic subtype, and find their vulnerabilities to - identify new targets for therapy. To address this issue, I will avail of relevant pre-clinical models developed in our laboratories and propose two complementary strategies: 1) a screening-based approach, focused either on the target, by analyzing - synthetic lethal interactions through CRISPR-based genome-wide interference, or on the drug, by high-throughput chemical libraries screenings; 2) a hypothesis-driven approach, based on our recent gained novel insights on the role of specific - intracellular pathways/genes in NPM1-mutated AML and on pharmacological studies with ‘old’ drugs, which we have revisited in the specific AML genetic context. I expect our discoveries will lead to find novel therapeutic approaches and make clinical - trials available to patients as soon as possible. - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Italy - - - ContraNPM1AML - - - ERC-2016-COG - - - 725725 - - - - - Fundacion IMDEA Energia - Fundacion IMDEA Energia - - - EUR 1 998 407 - - - Membrane-Free Redox Flow Batteries - - - EUR 1 998 407,01 - - - Spain - Spain - - - Research Organisations - Research Organisations - - The environmental concerns over the use of fossil fuels have promoted great interest in generating electric energy from renewable sources such as solar and wind. However, the intermittent nature of those resources demands high - performing and cost-effective energy storage systems. Redox Flow Batteries (RFBs) present several advantages, namely, total decoupling of power and energy densities and the possibility of rapid mechanical charging by substituting spent electrolytes - with fresh ones. The major issues of the current Vanadium RFBs are the high price and toxicity of vanadium components and the high cost and low performance of the ion-selective membranes they require. - - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Spain - - - MFreeB - - - ERC-2016-COG - - - 726217 - - - - - UNIVERSITY OF GLASGOW - UNIVERSITY OF GLASGOW - - - EUR 1 957 573,75 - - - A study of the roles of the immune and inflammatory systems in hypertension. - - - EUR 1 957 573,75 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Hypertension is a common disease impacting 1 billion people worldwide, which leads to catastrophic cardiovascular complications. The cause of primary hypertension is unknown and the disease remains uncontrolled in many - patients. By interrogating the key hypothesis that inflammatory dysregulation fundamentally controls development of hypertension and vascular remodelling, InflammaTENSION provides a new paradigm for the management of the disease, with the potential - to lead to identification of novel therapeutic targets to control hypertension. InflammaTENSION will result in the discovery of novel biomarkers, capable of identifying patients who could benefit from such immune targeted therapies. Importantly, we - already made the seminal observation that the immune system not only mediates target organ damage, but is essential for the development of hypertension. This finding has initiated numerous studies, that defined the roles of pro-inflammatory T cells, - monocytes and anti-inflammatory T regulatory cells. However, our current knowledge remains very fragmented and so far has not been applied to human pathology. InflammaTENSION will for the first time advance the knowledge procured in rodent models - into human studies. By combining clinical translational and model mechanistic studies it will identify novel inflammatory factors that can control immune mechanisms of hypertension. We will: (1) characterize the immunophenotypic signature of human - hypertension; (2) define key concepts in cytokine biology of hypertension with TNF-α and IL-6 as key exemplars; (3) understand how chronic cytokines regulate the T cell dependent mechanisms of hypertension. InflammaTENSION will go beyond current - state-of-the-art through comprehensive combination of immunology and cardiovascular medicine to create a new understanding of how the immune system may lead to human hypertension and will have major impact on the field, enabling translation of these - exciting findings to clinical practice. - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - InflammaTENSION - - - ERC-2016-COG - - - 726318 - - - - - ASTON UNIVERSITY - CORK INSTITUTE OF TECHNOLOGY - FUNDACIO INSTITUT CATALA DE NANOCIENCIA I NANOTECNOLOGIA - THE UNIVERSITY OF BIRMINGHAM - Teer Coatings Limited - - - EUR 720 000 - - - Diamond-based nanomaterials and nanostructures for advanced electronic and photonic applications - - - EUR 1 102 500 - - - United Kingdom - Ireland - Spain - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - We are proposing a 4-year program of knowledge transfer and networking between Aston University, UK (Aston), Cork Institute of Technology, Ireland (CIT), Institute of Nanoscience and Nanotechnology, Spain (ICN2), University of - Birmingham, UK (UoB), Zhejiang University of Technology, China (ZJUT), Nanotechplamsa Ltd, Bulgaria (NPL), B&T composites, Greece (B&T), National Institute for Research and Development in Electrical Engineering, Romania (ICPESA), and Teer - Coatings Ltd, UK (TCL). - - - 2021-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - United Kingdom - - - D-SPA - - - H2020-MSCA-RISE-2016 - - - 734578 - - - - - UNIVERSITY OF LEEDS - UNIVERSITY OF LEEDS - - - EUR 1 985 996 - - - The role of minerals in the oceanic carbon cycle - - - EUR 1 985 996 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The oceanic carbon cycle is key for regulating the Earth system because, in sediments and seawater, the balance between the degradation and preservation of organic carbon (OC) exerts a first order control on atmospheric CO2 - and O2. In sediments, OC is preserved over millions of years, while in seawater, a dissolved form of recalcitrant OC has been recently recognised as critical to OC storage over anthropogenic timescales. Both sedimentary and seawater OC are derived - from living organisms, and should therefore be easily degraded. Their persistence is therefore profoundly puzzling. Quite simply we do not know how or why OC is preserved. A long-standing hypothesis suggests that protection of OC inside minerals - might account for the vast OC stores preserved in sediments. In a NEW hypothesis, based on recent work by the PI and proposed here for the first time, the interaction of OC with minerals might ALSO account for the even larger stores of dissolved OC - preserved in seawater. Together these concepts could revolutionise our understanding of OC degradation and preservation, but the extent to which minerals preserve OC in sediments and seawater is (still) unknown, largely because the mechanisms that - control how OC interacts with minerals are almost entirely unconstrained. MINORG will quantify the role of minerals in the preservation of OC for the first time, by combining cutting-edge molecular-level techniques with the first ever comprehensive - and fully integrated experimental and modelling campaign, to determine in unprecedented detail the exact mechanisms responsible for the interaction of OC with minerals, and its subsequent degradation and preservation behaviour. MINORG hypothesises - that minerals play a MAJOR role in the preservation of OC, in both its sedimentary and seawater forms, and is uniquely poised to test this. This project will majorly contribute to our quantitative understanding of the oceanic carbon cycle, and so to - predicting current climate change. - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - MINORG - - - ERC-2016-COG - - - 725613 - - - - - TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY - TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY - - - EUR 150 000 - - - The development of Personalised Host Response Diagnostic kit - - - EUR 150 000 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Drug resistance is a major reason for failure in cancer chemotherapy and/or modern targeted drugs. While tumours usually initially respond to therapy, resistance occurs within several cycles of treatments, or later on when - patients are off therapy. Until recently, acquired and intrinsic resistance mechanisms for therapy were thought to be solely tumour driven. They are usually measured after tumours relapse or after several lines of treatments. However, in our ERC - starting grant (HostResponse No. 260633), we found a novel way to predict resistance to therapy, already after 24 hours after the first drug administration. This discovery resulted in a new stream of research by means of published papers and the - formation of special interest groups in cancer research and pharmaceutical disciplines that tackle this paradigm shift in cancer therapy. During our discussions with the cancer community, a clear need has emerged for a Specific Host-Driven Resistant - Mechanisms (SHDRM®) diagnostic platform which will serve two (closely connected) markets:(1) the research community – enabling researchers to further examine this new paradigm; and (2) Clinicians- enabling oncologists to identify each patient - specific host driven resistance mechanism and repurpose off-the-shelf drugs to counteract the specific factor driving the resistance. PHRD goal is to technically validate and develop a diagnostic platform Prototype for both markets including a - clinical study design report which will enable to secure our partners including drug manufacturers, diagnostic providers, and the research community to commit to jointly push the new PHRD standard. - - 2018-09-30, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Israel - - - PHRD - - - ERC-2016-PoC - - - 737467 - - - - - ECOLE NORMALE SUPERIEURE - ECOLE NORMALE SUPERIEURE - - - EUR 2 000 000 - - - Pushing the frontiers of biological imaging with genetically encoded fluorescence switches - - - EUR 2 000 000 - - - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Biological imaging is essential for revealing the inner workings of living systems. Among the numerous imaging modalities, light microscopy has revolutionized biological research. In addition to advances in optics and - detectors, imaging has benefited from the development of molecular tools to observe biomolecules in action. Although the last decade’s breakthroughs in imaging have led to new discoveries in biology, there are still extraordinary opportunities for - basic and clinical research in further advancing imaging capabilities. This project proposes to develop new classes of probes to advance biological imaging and allow the study of biological processes in all their complexity. First, I propose to push - the boundaries of multiplexing and super-resolution imaging in living cells developing a new class of fluorogenic probes that act as genetically encoded fluorescence on/off switches. Highly multiplexed images will be built up over sequential - activation of orthogonal fluorescence on/off switches, while continuous switching will allow implementing innovative dynamic super-resolution techniques in living cells. Then, I will develop dynamic fluorescence on/off switches enabling to reveal the - dynamics of intracellular processes, focusing in particular on the visualization of interaction dynamics in real-time, and the dynamic detection of endogenous molecules (e.g. proteins, nucleic acids) in living cells. The final part will be dedicated - to the development of probes acting as molecular integrator switches to identify active cell circuits in whole tissues or organisms through permanent labeling of transiently activated cells. Overall, this project will enable to push back the - frontiers of biological imaging providing innovative tools to interrogate quantitatively and comprehensively living systems at the molecular, cellular and network levels. - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - France - - - FLUOSWITCH - - - ERC-2016-COG - - - 724705 - - - - - INSTITUTO NACIONAL DE INVESTIGACIONY TECHNOLOGIA AGRARIA Y ALIMENTARIA OA MP - INSTITUTO NACIONAL DE INVESTIGACIONY TECHNOLOGIA AGRARIA Y ALIMENTARIA OA MP - - - EUR 1 866 046 - - - Teleost mucosal B1-like lymphocytes at the crossroad of tolerance and immunity - - - EUR 1 866 046 - - - Spain - Spain - - - Research Organisations - Research Organisations - - B cells are one of the main players of immunity, responsible for the production of immunoglobulins (Igs). In 2011, I was granted an ERC Starting grant to undertake the phenotypical and functional characterization of teleost B - lymphocytes based on the hypothesis that they do not behave as mammalian B2 cells (conventional B cells) but closely resemble mammalian innate B1 lymphocytes involved in extrafollicular T-independent (TI) responses. Since then, my laboratory has - gathered considerable evidences that strengthen this hypothesis. These studies were mostly carried out in central lymphoid compartments, but did not address how teleost B1-like cells regulate the delicate balance between immunity and tolerance at - mucosal interfaces, in species lacking follicular structures. In this new project, I want to pursue my studies on B lymphocyte functionality, focusing on how teleost mucosal B cells are regulated, still under the assumption that fish B lymphocytes - resemble better a B1 model. We will study how fish B cells differentiate to antibody secreting cells (ASCs) and establish extrafollicular long-term memory, taking into account novel results in mammals that have challenged traditional paradigms and - revealed that long-term immunological memory can be established through TI IgM B1-like responses. Furthermore, we will also study the role of IgD in the gills, as previous studies from my group suggest that this Ig plays a key role in the regulation - of immunity in this specific mucosa, as it seems to do in humans in areas such as the upper respiratory tract. - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Spain - - - TEMUBLYM - - - ERC-2016-COG - - - 725061 - - - - - UNIVERSITAT JAUME I DE CASTELLON - UNIVERSITAT JAUME I DE CASTELLON - - - EUR 1 999 071,53 - - - Boosting Photovoltaic Performance by the Synergistic Interaction of Halide Perovskites and Semiconductor Quantum Dots - - - EUR 1 999 071,53 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Photovoltaic conversion has the extraordinary property of transforming the solar energy directly into electric power. However, the available electrical power is known to be severely limited by the so-called Shockley-Queisser - (SQ) photoconversion limit. The maximum efficiency for a single absorber is limited as photons with energy lower than the bandgap (BG) cannot be absorbed, and just an energy equivalent to the BG can be used for photons with higher energy than the BG, - due to thermalization. Tandem cells have overcome this SQ limit upon exploiting complex and expensive configurations. Alternative approaches, even with higher potentiality, as Intermediate Bandgap Solar Cells (IBSCs) have not reached the expected - performance mainly due to the limitations introduced by the monocrystalline matrix. The incorporation of quantum dots (QD) to create the IB produces layer strain and defects that limit the cell performance. No-LIMIT proposes to revamp IBSCs concept, - using polycrystalline halide perovskites (HP) host matrix in order to take benefit from the strain relaxation at polycrystalline materials and from HP benign defect physics. HPs show an outstanding performance even when they are grown in a porous - structure, indicating that their excellent transport and recombination properties are preserved with embedded materials. No-LIMIT will exploit this potentiality by using the states of embedded QD as IB in IBSC with HP matrix. The project will focus - on the preparation of HPs-QD systems with enhanced light collection efficiency preserving charge transport, recombination and stability. No-LIMIT will study the properties and interactions of the HP and QD materials developed, as well as injection, - recombination and transport properties in the coupled system. The combination of these strategies will build a ground-breaking synergistic system able to break the SQ limit. The achievements of IBSC, together with the intermediate steps, will have a - colossal impact on photovoltaics - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Spain - - - No-LIMIT - - - ERC-2016-COG - - - 724424 - - - - - LUNDS UNIVERSITET - - - EUR 173 857,20 - - - Theory, Computation and Application of Characteristics Modes - - - EUR 173 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - The proposal focuses on Theory of Characteristic Modes(TCM), a reasonably general methodology to systematically design and analyse arbitrary antennas in wireless communication systems by providing accurate physical insights of - the working mechanism. With the rise of the diverse and complex requirements of modern antenna systems, the existing TCM is not sufficiently effective to handle critical design problems such as multi-scale vehicular antenna systems and large-scale - massive MIMO base station arrays, which leads to an urgent need for further improvement of TCM. - - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - TECAM - - - H2020-MSCA-IF-2016 - - - 749598 - - - - - UNIVERSITA DEGLI STUDI DI FIRENZE - UNIVERSITA DEGLI STUDI DI FIRENZE - - - EUR 1 689 272 - - - Economic Uncertainty and Fertility in Europe - - - EUR 1 689 272 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - EU-FER is a project about Economic Uncertainty and FERtility in EUrope. Economic uncertainty may be interpreted as an individual risk factor, mainly related to the labour market (e.g. unemployment, short-term contract jobs, - underemployment, or a combination of these), but it may also be conceptualized as a macro-level phenomenon, reflecting the general uncertainty felt by people in times of economic turbulence. The recent Great Recession, spanning 2007 to 2009 and - featuring downturns in both financial and labour market fortunes, has fuelled interest in understanding whether economic uncertainty, which does not appear to be a transient phenomenon, affects fertility. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Italy - - - EU-FER - - - ERC-2016-COG - - - 725961 - - - - - UNIVERSITAT WIEN - UNIVERSITAT WIEN - - - EUR 1 498 279 - - - Illuminating Functional Networks and Keystone Species in the Gut - - - EUR 1 498 279 - - - Austria - Austria - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - We live in an intimate symbiosis with our gut microbiota, which provides us services such as vitamin production, breakdown of dietary compounds, and immune training. Sequencing-based approaches that have been applied to - catalogue the gut microbiota have revealed intriguing discoveries associating the microbiome with diet and disease. The next outstanding challenge is to unravel the many activities and interactions that define gut microbiota function. - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Austria - - - FunKeyGut - - - ERC-2016-STG - - - 714623 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 183 454,80 - - - Role of calcium fluxes in mitochondrial dynamics - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Mitochondria house hundreds of biochemical reactions involved in processes critical for the survival and homeostatic adaptation of the cell. Mitochondria are highly dynamic organelles, which adapt their shape and network - depending on the cellular needs. As mitochondria play a central and unique role in metabolism, our understanding of the complex network of interrelations between mitochondria and other organelles has crucially changed our view on the cell biology of - mitochondria and a new biology and pathophysiology of this organelle are emerging. Mitochondria are in dynamic contact with the endoplasmic reticulum (ER) and this specialized contact is essential for a number of relevant processes, including - mitochondrial dynamics, lipid exchange, calcium homeostasis and apoptosis. The Mitochondrial Calcium Uniporter (MCU) and some of its regulators (MICU1-3, EMRE) have recently been identified as the key complex regulating mitochondrial calcium uptake - with some already identified functions. The goal of this project is to define the complete interactome of the Mitochondrial Calcium Uptake Machinery (MCUM) in different physiological conditions and to characterize the functions associated to this - complex. To address these goals, an unbiased proteomic analysis will be performed, both in cellulo (human cells) and in vivo (zebrafish), to identify the interactors of the MCUM at steady state and under different cellular stresses using the BioID - technic. The mechanisms involving the MCUM in the regulation of mitochondrial dynamics, apoptosis and cell migration will be unravelled using molecular and cell biology experiments coupled with the most recent advances in microscopic analysis. - Finally, we will explore the relevance of these findings in the physiopathology associated to mitochondrial diseases using cell lines derived from patients harbouring a MCUM dysfunction. - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - United Kingdom - - - MITODYN - - - H2020-MSCA-IF-2016 - - - 749926 - - - - - KOBENHAVNS UNIVERSITET - - - EUR 200 194,80 - - - Live, In vivo Visualisation of liver Regeneration in Zebrafish After Photoablation of hepatocytes - - - EUR 200 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - The specialised tissue architecture of the liver is crucially important for its essential metabolic functions in the body. The liver has the unique regenerative capacity to restore lost architecture when damaged. However, this - remodelling process is compromised in chronic liver disease by scarring and cirrhosis. Often the only treatment is organ transplantation, thus the development of novel therapies is of vital importance. The necessary understanding of the dynamic cell - rearrangement driving restoration of liver architecture has been limited by temporally static histological analyses of fixed regenerating tissue. Real-time monitoring of the mammalian liver is hindered by tissue opacity and deep organ position, - whereas the surface location of the zebrafish liver and larval transparency makes this species uniquely suited for live, in vivo imaging of regeneration. LIVERZAP will generate a detailed map of the different cell behaviours driving restoration of - liver architecture by pioneering real-time, in vivo imaging of regeneration in zebrafish. This will be achieved by: i) generating a novel, photoactivatable method for rapid hepatocyte ablation and ii) developing a deep tissue, 2-photon microscopy - live imaging protocol. The molecular factors controlling the identified cell behaviours will be screened for using SILAC-based proteomics. To realise LIVERZAP, expertise in liver research, deep tissue microscopy and proteomics within the host - environment will be combined with the fellow’s live imaging experience. LIVERZAP will generate excellent new tools for the regeneration community and greatly enhance the fellow’s competencies in specialised techniques, including cutting-edge - microscopy systems and optogenetics. The outcomes of LIVERZAP will produce essential insights into the cellular and molecular mechanisms driving restoration of liver architecture following injury, providing a platform for the long-term development of - therapies for human liver pathologies. - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - LIVERZAP - - - H2020-MSCA-IF-2016 - - - 751085 - - - - - TEL AVIV UNIVERSITY - TEL AVIV UNIVERSITY - - - EUR 1 971 875 - - - Aligning pigmentation and repair: a holistic approach for UV protection dynamics - - - EUR 1 971 875 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The human body takes different measures in order to protect itself against the results of UV exposure and its accompanied hazards, such as skin cancer. Despite extensive studies regarding the molecular regulation of the two - main UV protection mechanisms, namely, the DNA repair system and the pigmentation system, a comprehensive theory that simultaneously accounts for the two systems is still missing. Hence, the ground-breaking goal of this proposal is to elucidate, for - the first time, the dynamic control used to schedule and synchronize the UV protection subsystems. - - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Israel - - - UVdynamicsProtection - - - ERC-2016-COG - - - 726225 - - - - - UNIVERSITEIT GENT - - - EUR 172 800 - - - Fiction, Imagination, and Early Cinema - - - EUR 172 800 - - - Belgium - - - Higher or Secondary Education Establishments - - "The project investigates two closely interrelated issues: what is the role of imagination in early cinema and what does it mean for a representational work to be fictional? Specifically, it asks what the criteria are - according to which we categorize texts as fictional and what counts as proof for reconstructing the experience of historical spectatorship. The project innovatively proposes that the period between 1880 and 1915 provides a unique opportunity for - construing how a representational medium becames employed in the production of fictions and the crucial role the discourse on imaginary engagement plays in this process. In other words, the project asks why we engage some films as fictions and other - as documentaries despite the fact that they are both based on actuality material – photographs. For instance, why, when watching Méliès’ 1898 The Astronomer’s Dream or the Man in the Moon, do we nowadays regularly say that we are watching an - astronomer whose gazing at the moon turns into a series of fantastical mishaps? Why do we engage such a film as a fiction rather than as a documentary of actors performing in front of painted sets? Especially if during the early era, such films were - regularly seen as instances of “canned theater”, i.e. as documentaries of theatrical performances. - - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Belgium - - - FIEC - - - H2020-MSCA-IF-2016 - - - 746619 - - - - - HELSINGIN YLIOPISTO - HELSINGIN YLIOPISTO - - - EUR 2 211 564,75 - - - Individualizing statin therapy by using a systems pharmacology decision support algorithm - - - EUR 2 211 564,75 - - - Finland - Finland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Background: Statins are essential drugs in the treatment of hypercholesterolaemia and are among the most prescribed drugs worldwide. The response to statin therapy varies widely between individuals. While most patients show - good efficacy, a significant proportion of individuals show poor or even a lack of cholesterol-lowering efficacy. Moreover, a number of patients experience adverse drug reactions. These together with the lack of immediate effect on well-being likely - explain the relatively poor adherence to statin therapy. Poor adherence to statins in turn increases the incidence of cardiovascular events and mortality. - - 2022-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Finland - - - IndiviStat - - - ERC-2016-COG - - - 725249 - - - - - KOBENHAVNS UNIVERSITET - - - EUR 212 194,80 - - - New Frontiers in Modeling Planet-Disk Interactions: from Disk Thermodynamics to Multi-Planet Systems - - - EUR 212 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - Recent space missions such as CoRoT and Kepler have revolutionized exoplanetary science. Today, we know of thousands of systems with awide diversity of architectures, proving that our Solar System is not typical. Understanding - how these systems form and evolve is currently one of the most active area of astrophysics. The processes that dictate the dynamics of planets play a fundamental role in shaping the architecture of the systems we observe. In the present paradigm, as - planets accrete mass from the primordial disk, they are subject to interactions with it and with other planets. These interactions exert torques, and make the planets migrate. Disk-planet interactions depend strongly on the physical processes - governing the dynamics of the disk. I demonstrated a clear example of this in a recent paper in Nature, showing that the disk heating by an accreting embryo have a strong impact on the torques. This proposal has two objectives with the potential to - produce a leap forward in our understanding of the long-term evolution of planetary systems. (i) I will produce the most advanced framework to date for investigating planetary migration in magnetohydrodynamic disk simulations, including ohmic, - ambipolar and Hall effects. I will do this self-consistently by considering the chemical evolution of the dusty gas. Calculating its ionization state and opacity, will moreover allow me to incorporate radiation more realistically. (ii) I will build - on a new technique that I have developed, the use of 3D radially moving meshes. This groundbreaking technique enables to follow the migration of multiple planets allowing studying their long-range migration. I want to carry out this research program - at The Niels Bohr Institute. The combined expertise of the groups in Copenhagen, together with their impressive computational resources, provide an unparalleled environment to achieve my research goals and develop myself as a leading international - figure in this rapidly evolving field. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - DiskTorqueOnPlanets - - - H2020-MSCA-IF-2016 - - - 748544 - - - - - KOBENHAVNS UNIVERSITET - - - EUR 260 227,80 - - - Very-Large-Scale Quantum Photonic Processing - - - EUR 260 227,80 - - - Denmark - - - Higher or Secondary Education Establishments - - Optical systems operating at the quantum regime have recently enabled the detection of gravitational waves; new forms of ultra-secure communications; and high-fidelity manipulation of quantum states for quantum computing. - Maintaining this progress requires breakthroughs in quantum photonic architectures to process many optical modes with exceptional speed and precision. Fortunately, progress in optical interconnects has culminated in the development of silicon - photonic integrated circuits, enabling photonic devices to be combined virtually losslessly at orders of magnitude higher component density than possible with traditional methods. Here, we propose to leverage these advances to meet the stringent - requirements of optical quantum information processing bringing together state-of-the-art single photon source technologies and large-scale silicon photonic circuits: (1) Leveraging state-of-the-art silicon photonics fabrication processes to build a - large-scale 10-photon quantum photonic processor; fully integrated with on-chip photon sources, pump engineering and reconfigurable circuitry. (2) Interfacing solid-state quantum emitters with silicon photonic circuitry, enabling deterministic - generation and large-scale manipulation of single photon states. These very-large-scale quantum photonic processors (VLS-QPP) will provide several orders of magnitude speedups compared with current technologies, demonstrate practical quantum - algorithms for quantum chemistry and machine learning, and provide a clear route towards scalable photonic quantum technologies. To enable these advances this fellowship proposes a clear training plan, at two world-leading institutions, towards - developing the necessary diverse skill set to propel the field forward in new directions. - - 2020-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Denmark - - - VLS-QPP - - - H2020-MSCA-IF-2016 - - - 751016 - - - - - THE FRANCIS CRICK INSTITUTE LIMITED - THE FRANCIS CRICK INSTITUTE LIMITED - - - EUR 2 000 000 - - - Hold it or let it go: a niche decision on cancer growth - - - EUR 2 000 000 - - - United Kingdom - United Kingdom - - - Research Organisations - Research Organisations - - The tumour microenvironment or niche is the vital non-cancerous compartment of the tumour structure. Thus, targeting its tissue-derived cells represents a promising avenue to better therapeutic interventions. However, - knowledge about the tissue cells taking part of the tumour niche during early cancer development and later progression is lagging behind due to the difficulty of analysing and following early tissue changes in the surrounding of cancer cells in vivo. - In our research proposal we will use a combination of original tools developed in the lab and state of the art technologies to overcome some of these constraints and expand our understanding of which cells in the niche support early cancer cell - growth. We also aim to reveal their mechanism of action and identify approaches to block the niche supportive activity. Our five-year plan has three main objectives (I, II, III), which we will meet using two original strategies. With the first - strategy we will visualize the early tumourigenic niche in vivo. This will allow us (I) to identify and characterize novel cellular components during dynamic niche evolution both in the context of metastatic colonization as well as during primary - tumour onset. We will also use this original approach (II) to deepen our understanding of neutrophils in cancer, a particularly crucial emerging component of the cancer niche, whose role is still debated. - - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - WHOLENICHE - - - ERC-2016-COG - - - 725492 - - - - - BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION - - - EUR 170 121,60 - - - Near-term predictability of net primary production in the Atlantic Ocean - - - EUR 170 121,60 - - - Spain - - - Research Organisations - - The main goal of this research project is the improvement of near-term (i.e. seasonal to decadal) predictions of Net Primary Production (NPP) in the Atlantic Ocean. NPP is the rate of production of phytoplankton biomass, the - primary source of food for marine animal life and thus a fundamental environmental variable to be taken into account in fishery management strategies. The activities proposed are based on a suite of simulations with an Earth System Model (ESM). These - simulations include reconstructions of the biogeochemical state of the Atlantic ocean for the period 1960 to present and a set of near-term predictions initialized every 3 years for the period 1979 to present. The simulations are designed to test the - ability of two different initialization techniques to provide predictive skill to the NPP prediction. One initialization technique is based on data-assimilation of physical fields only. As an absolute novelty, the second technique proposed is based - on the reconstruction of 3D nutrient fields. This combines information from climatological nutrient fields and reconstructed water masses variability. This combination is meant to exploit the ability of Atlantic mode waters to propagate a signal on - nutrient distribution on interannual timescales providing a source of predictability for nutrients and thus for NPP. Skill scores will be used to validate the near-term predictions derived from both techniques and the best performing one will be - extended to 10-year forecast and initialization every year in order to obtain a complete evaluation of the predictive capability of the modeling system (ESM+initialization technique). - - 2019-01-08, ongoing project - - - 2017-01-09 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - NeTNPPAO - - - H2020-MSCA-IF-2015 - - - 708063 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 195 454,80 - - - Molecular determination of Rif1-Associated Genomic Elements and their function in regulating genome activity and integrity - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - DNA double-strand breaks (DSBs) are highly toxic and must usually be accurately repaired to prevent oncogenic mutations. However, DSBs also represent necessary intermediates of recombination events required to create genetic - diversity in immune repertoires and the germline. These distinct cellular contexts require that DSBs are differentially metabolised to achieve the required genetic outcome. Thus a complex system has evolved to regulate DSB repair. Rif1 was recently - identified as a critical regulator of DSB repair, recruited to chromatin at DSBs by the 53BP1 chromatin reader. However, little is known about how these proteins cooperate to alter the chromatin landscape at DNA damage sites, and how this influences - DNA repair decisions. Understanding the molecular basis of these proteins function is paramount, as misregulation at the level of Rif1/53BP1 is known to drive disease: loss of either protein results in primary immunodeficiency, while an inability to - counteract Rif1/53BP1-dependent activities during DNA repair is associated with genomic instability that drives carcinogenesis. Interestingly, recent evidence suggests that Rif1 may also mediate gene-repression in certain chromatin contexts. This - raises the possibility that the manner by which Rif1 regulates transcriptional control may be similar to its role in DNA repair. In this proposal, I seek to test my hypothesis that Rif1 mediates repressive chromatin states to regulate both - transcription and DNA repair outcomes. My preliminary work and an array of unique cell lines and molecular reagents developed by my host laboratory, provide me with a unique and timely opportunity to examine this fascinating protein, and develop a - better understanding of potentially common regulatory mechanisms that govern transcription and DNA repair. - - 2019-03-31, ongoing project - - - 2016-03-31 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - RAGES - - - H2020-MSCA-IF-2014 - - - 656357 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 183 454,80 - - - Leggett-Garg test of a vibrating carbon nanotube - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Despite the undeniable success of quantum mechanics, the boundary between quantum and classical mechanics remains unclear. Leggett and Garg devised a class of inequalities that provide the script for a quantitative test to - determine whether a macroscopic object would indeed be at all times in one of its distinct states or whether quantum mechanics would prevail. I will perform the first Leggett-Garg test on a massive moving object: a carbon nanotube resonator. This - ambitious experiment would be a key accomplishment in mapping the persistence of quantum features in systems of increasing macroscopicity. - - 2018-02-28, Grant Agreement terminated - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - LeGaNa - - - H2020-MSCA-IF-2014 - - - 658989 - - - - - CPNU - CENTAR ZA PROMOCIJU NAUKE IUMETNOSTI DRUSTVO SA OGRANICENOM ODGOVORNOSCU BEOGRAD - INSTITUT MIHAJLO PUPIN - UNIVERSITY OF NIS- FACULTY OF ELECTRONIC ENGINEERING - UNIVERZITET U KRAGUJEVCU - Faculty of Mathematics, University of Belgrade - - - EUR 144 143 - - - Fall in Love wIth Research Tonight - - - EUR 181 679 - - - Serbia - Serbia - Serbia - Serbia - Serbia - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The FLIRT proposes a project that is based on the idea that falling in love with science is just as exciting as falling in love with a real person, and shows how a passionate “crush” can develop into real love. - - 2015-11-30, closed project - - - 2014-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.5."> - - - MSCA-NIGHT-2014 - European Researchers' Night (NIGHT) - - - CSA - Coordination and support action - - - Serbia - - - FLIRT - - - H2020-MSCA-NIGHT-2014 - - - 633398 - - - - - AARHUS UNIVERSITET - UNIVERSITY OF KENT - WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER - MARTIN-LUTHER-UNIVERSITAET HALLE-WITTENBERG - UNIVERSITA CATTOLICA DEL SACRO CUORE - UNIVERZITA KARLOVA - THE UNIVERSITY OF READING - - - EUR 3 651 149,88 - - - The History of Human Freedom and Dignity in Western Civilization - - - EUR 3 651 149,88 - - - Denmark - United Kingdom - Germany - Germany - Italy - Czech Republic - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The ETN has two aims: to a) train ESRs; b) investigate the The History of Human Freedom and Dignity in Western Civilization. - - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Denmark - - - HHFDWC - - - H2020-MSCA-ITN-2015 - - - 676258 - - - - - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 1 834 975 - - - Analysis, Verification, and Synthesis for Infinite-State Systems - - - EUR 1 834 975 - - - Germany - Germany - United Kingdom - - - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Research Organisations - Volker Maria Geiss - Tel.: +4968193255700 - Fax: +4968193255719 - Higher or Secondary Education Establishments - - The central objective of this project is to investigate key algorithmic verification questions concerning two fundamental mathematical structures used to model and analyse infinite-state systems, namely discrete linear - dynamical systems and counter automata, in both ordinary and parametric form. Motivated especially by applications to software model checking (more specifically the termination of linear loops and predicate abstraction computations), as well as - parametric real-time reasoning and the verification of Markov chains, we will focus on model-checking, module-checking, and synthesis problems for linear dynamical systems and one-counter automata against various fragments and extensions of Linear - Temporal Logic (LTL) specifications. The key deliverables will be novel verification algorithms along with a map of the complexity landscape. A second objective is then to transfer algorithmic insights into practical verification methodologies and - tools, in collaboration with colleagues in academia and industrial research laboratories. - - 2020-07-31, ongoing project - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - AVS-ISS - - - ERC-2014-CoG - - - 648701 - - - - - UNIVERSITATEA DE STIINTE AGRONOMICE SI MEDICINA VETERINARA - BUCURESTI - UNIVERSITATEA DUNAREA DE JOS DIN GALATI - UNIVERSIDAD POLITECNICA DE MADRID - - - EUR 580 500 - - - Researches on the potential conversion of conventional fish farms into organic by establishing a model and good practice guide - - - EUR 580 500 - - - Romania - Romania - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The conversion of conventional aquaculture farms in sustainable aquaculture farms help aquaculture businesses to achieve economic viability and competitiveness. Sustainable aquaculture is undoubtedly the management technique - that has most contributed to support aquaculture businesses to adopt aqua-environmental measures for protection of the environment, natural resources and landscape. - - 2019-05-31, ongoing project | - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Romania - - - ECOFISH - - - H2020-MSCA-RISE-2014 - - - 645691 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 195 454,80 - - - Composite-particle approach to Symmetry Protected Topological Phases - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The sum being greater than its parts is a common theme in condensed matter physics. Materials made of large numbers of simple constituents often exhibit intriguing and markedly distinct phases of matter with properties very - different from any of the individual constituents. Understanding the possible phases of matter and identifying them in real materials is the central focus of this branch of physics. Roughly speaking, two categories of phases of matter exist--- - conventional phases which show a geometrical pattern of order, and topological phases, where the order is more elusive and related to topological concepts. In the past three decades, topological phases have attracted a large amount of interest due to - their tendency to exhibit highly robust quantum phenomena which has various applications in quantum engineering and metrology. The current frontier in the field aims at understanding the variety of novel topological phases which arise when some extra - symmetries, such as time reversal, are not allowed to be broken. In this project we explore this new type of phase using the concept of composite particles --- an idea which has been extremely useful in previous studies of topological matter, but has - not been applied in the symmetry-protected context previously. The fundamental idea behind our approach is to view symmetry protected topological (SPT) phases of spin/electron systems as conventional ferromagnets/superconductors/metals of composite - objects. Besides its conceptual importance, such an approach will allow us to utilize our knowledge of conventional phases in the context of SPT phases and also derive microscopic models which realize these states of matter. It will thus increase the - chance of discovering new SPT phases in nature. - - 2017-03-31, closed project | - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - CompositeSPTphases - - - H2020-MSCA-IF-2014 - - - 657111 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 183 454,80 - - - New Approaches to Metallo-β-Lactamase Inhibitors - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The increasing problem of antibiotic resistance is a major global public health concern. In the EU 25,000 patients die each year due to infections caused by multi-resistant bacterial pathogens, and the EU spends at least 1.5 - billion euro per year on healthcare costs. The β-lactam antibiotics are the most important antibiotics representing >60% of small molecules in clinical use. BLAs contain a β-lactam ring which is critical for penicillin-binding protein inhibition. - However, BLA efficacy is declining due to resistance mechanisms including the widespread occurrence of β-lactamases, which catalyse β-lactam hydrolysis. Metallo-β-lactamases, long-considered as of little clinical relevance, now present a serious - global threat to almost all BLAs, rendering the development of approaches to MBL inhibitors important. Unlike the serine β-lactamases, the MBLs are structurally and mechanistically unrelated to PBPs, and are not inhibited by current mechanism-based - SBL inhibitors. Due to variations in MBL structures, a major challenge in MBL inhibition is the development of compounds with the breadth of selectivity necessary for clinical utility. Society is now in an alarming situation and there is a clear need - for the development of an MBLI:β-lactam-based combination therapies. The aim of my proposed work is to pioneer, enable and inspire the generation of broad-spectrum MBLIs active against a panel of clinically representative MBLs, but inactive against - human enzymes with related active sites. To obtain the desired objective, novel approaches are proposed and include the use of phosphonates and phosphinic acids for: (a) MBL-directed DCC coupled to analysis by non-denaturing ESI-MS and 31P-NMR, (b) - 31P-NMR reporter screening method, (c) pre-equilibrated DCLs for MBL-directed DCC, and (d) the synthesis of modified inhibitors. The study will be interdisciplinary and encompass organic synthesis, biological MS/NMR, structural biology, and medicinal - chemistry. - - 2017-06-30, closed project | - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - MBLIs - - - H2020-MSCA-IF-2014 - - - 657314 - - - - - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - - - EUR 173 076 - - - Role of GABAergic microcircuits with different embryonic origins in the orchestration of early cortical dynamics in the awake mouse pup - - - EUR 173 076 - - - France - - - Research Organisations - - Because of its function in brain wiring and in the generation of early correlated activity patterns, the maturation of GABAergic transmission plays a key role in enabling brain complexity in higher mammals. Indeed, disruption - of GABAergic circuitry at several time points can contribute to the generation of developmental disorders such as schizophrenia, autism or epilepsy (Le Maguerise and Moyner, 2013). Both in the murine hippocampus and neocortex, GABAergic interneurons - have been shown to participate in the emergence of a precise temporal sequence of distinct correlated neuronal activity patterns during early postnatal development (Crepel et al., 2007; Allene et al., 2008). In particular, GABAergic cells with an - extended and divergent axonal connectivity (operational “hub” neurons) (Bonifazi et al., 2009; Picardo et al., 2011; Cossart, 2013) have been described to be capable of synchronizing single-handedly populations of cells in developing hippocampal - slices (Bonifazi et al., 2009). This project builds up on a solid ground of unpublished in vitro data from the host lab indicating that a specific, but diverse functional subpopulation of GABA neurons could also operate as hub cells in the developing - neocortex. Experimentally, it will benefit from recent technical developments from the host lab aiming at manipulating and visualizing the activity of single neurons in the awake mouse combining genetic and microscopy tools. Indeed, if operational - hub neurons have been described in vitro, it remains unknown how they integrate into functional networks in vivo, and more generally how GABAergic activity shapes early cortical network dynamicsThis proposal aims at translating from the in vitro to - the in vivo situation a multidisciplinary approach to investigate the functional contribution of specific microcircuits to the emergence of network dynamics during development. - - 2017-03-31, closed project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - GABACODEV - - - H2020-MSCA-IF-2014 - - - 660795 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 91 727,40 - - - Deformations of fundamental Groups of REpresentATions - - - EUR 91 727,40 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The aim of this project is to consider X a smooth projective algebraic curve and a representation ρ of π1(X) into a semisimple Lie group G, and study deformations of ρ when X deforms into a singular curve. This question will - open a brand new direction in the theory of representations of fundamental groups and G-Higgs bundles. The main tool to approach the problem will be non- abelian Hodge theory to transform this topological question into the geometric one. Then we use - recent new developments in the classification of representations together with new algebraic objects which recently appear in non-abelian Hodge theory to study this question. It will take us to the study the deformations of G-Higgs bundles together - with deformations of harmonic bundles over X when X is a curve and varies. - - 2016-12-31, closed project | - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - GREAT - - - H2020-MSCA-IF-2014 - - - 654490 - - - - - THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN - - - EUR 195 454,80 - - - Delineation of a brain circuit regulating energy expenditure to impact body weight - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Obesity is now a global epidemic with a significant and deleterious impact on human health. My career aim is to clarify the neural underpinnings of energy expenditure (EE) given that this makes a significant contribution to - body weight. During my early career, I discovered a circuit linking the ventromedial hypothalamus (VMH) to brown adipose tissue (BAT) and inducing thermogenic beige (browning) white adipose tissue (WAT), regulating EE. Moreover, I found that the - VMH-BAT axis is utilized by estrogen (Cell Metabolism, 2014) and nicotine (Diabetes, 2012) to increase EE and decrease body weight. My preliminary data indicate that a critical node between the VMH and BAT is the raphe pallidus (RPa), a brain region - known to drive sympathetic tone to BAT. My immediate career aim is to clarify the neurochemical communicator receiving the VMH-EE related input and transmitting to BAT and browning. Given that the RPa is rich in the neurotransmitter - 5-hydroxytryptamine (5-HT) which plays a role in thermoregulation, I hypothesize that 5-HT is a crucial component of my circuit. I propose to perform a Marie Sklodowska-Curie Fellowship (MSC) under Prof Lora Heisler’s supervision, arguably the global - leader in 5-HT obesity research. Her laboratory is in the Rowett Institute of Nutrition and Health, University of Aberdeen, an Institute with more than a century of focused state-of-the-art obesity and nutrition research. This will supply an optimal - environment for a MSC providing me with the opportunity to broaden my research interests, and allowing me to construct an international network of obesity researchers. A MSC will also provide the opportunity for me to be trained in transferable next - generation engineered genetic technology that will allow me to rigorously and definitively test my current research hypothesis and to provide state-of-the-art expertise that will form a platform for my future career. - - 2018-01-31, closed project - - - 2016-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - NeuroEE - - - H2020-MSCA-IF-2014 - - - 660219 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 183 454,80 - - - In vivo pharmacogenetic investigation of 5-HT mechanisms in emotional learning - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Emotional health and well-being is widely accepted to be crucial for healthy life and the success of societies. Anxiety and depression are two common and debilitating emotional disorders, with highly negative social and - financial implications. Serotonin (5-hydroxytryptamine; 5-HT) is thought to be critical to the healthy mood regulation and strongly implicated in the vulnerability to anxiety and depression. Importantly, accumulating evidence suggests that 5-HT’s - main influence is upon emotional learning rather than on mood directly. The objective of this proposal is to determine the neural mechanisms through which changes in 5-HT levels, within defined neuronal circuits, affect learning and memory for - aversive emotional experiences. New pharmacogenetic techniques will be developed that allow the selective triggering of 5-HT neuron activation and then inhibition in the same animal. We will use this technology to stimulate or inhibit 5-HT release in - the basolateral amygdala, a brain area that is crucial for aversive learning, whilst an animal is engaged in an emotional processing task. Through this we will learn how 5-HT modulates neuronal activity in the amygdala at critical time-points during - the encoding and retrieval of aversive memories. The results from these studies will provide entirely new insights into how 5-HT modulates amygdala information processing and aversive learning. Understanding how 5-HT affects emotional learning will - ultimately lead to a deeper understanding of healthy mood states and the biological mechanisms underlying vulnerability to disorders such as anxiety and depression. - - 2018-06-30, ongoing project - - - 2016-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - 5HT-DREADD - - - H2020-MSCA-IF-2015 - - - 709129 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 195 454,80 - - - Bioelectrochemical Sensing of Sexually Transmitted Diseases - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The detection of sexually transmitted diseases (STDs) has become a serious medical concern around the globe, as the number of reported cases increases every year, particularly in the United Kingdom. Infection with STDs, such - as Gonorrhea and Chlamydia can result in long term health issues, such as infertility, reproductive tract cancer, and poor perinatal outcome. The successful treatment of these diseases depends on a quick and reliable method of diagnosis, which will - be the topic of this proposal. The overall goal of the proposed research is to develop a detection method for bacteria, associated with STDs, based on bioelectrochemical techniques. - - 2018-09-14, ongoing project - - - 2016-09-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - United Kingdom - - - BSSTD - - - H2020-MSCA-IF-2015 - - - 702009 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 183 454,80 - - - Large Area Nanoparticle Deposition System - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - I intend to travel to the University of Oxford and the lab of Dr. Moritz Riede and build a second generation version of the Large Area Nanoparticle Deposition System (LANDS) that I have designed and built during my PhD studies - at Stanford University in the USA. This will be a flexible, particle-agnostic system that will be capable of depositing uniform films of nano- and micro-particles from solution. It is designed to emphasize scalability, high throughput and large area - film uniformity and will be compatible with low-temperature flexible plastic and foil substrates and the devices built on them. Once complete, I will initially use the LANDS to deposit nanostructured thin films of metal nanowires to form transparent - conductive electrodes for photovoltaic applications. I will continue to develop and explore the use of such metal nanowire films as replacements for industry standard transparent conductive oxides such as indium tin oxide (ITO) and fluorine doped tin - oxide (FTO) especially in flexible devices. - - 2017-08-11, closed project - - - 2015-08-12 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - LANDS - - - H2020-MSCA-IF-2014 - - - 659667 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 195 454,80 - - - Using SP1 to control plastid development and yield in cereals - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Recently, the host lab found that a novel ubiquitin E3 ligase, SP1, regulates the translocon of the outer chloroplast membrane (TOC), which is responsible for importing nucleus-encoded proteins into plastids. SP1 achieves this - by promoting the degradation TOC components by the cytosolic 26S proteasome. This is the first time the ubiquitin proteasome system (UPS) has been shown to directly regulate plastid development and function. By increasing or decreasing SP1 levels in - transgenic Arabidopsis plants, multiple effects of SP1 were observed; e.g., inefficient de-etiolation leading to low survival rates and delayed leaf senescence in sp1 null mutants (Science 2012, 338:655-9). Also, sp1 mutants are significantly more - sensitive to stress (unpublished). These data suggest that SP1 is important for the differentiation and interconversion of different plastid types, and all of the effects are highly correlated with plant growth and yield. Thus, discovery of SP1 - strongly suggests potential applications in agriculture, such as delaying leaf senescence to produce a staygreen phenotype, or controlling amyloplast development during grain development, by modifying SP1 expression. This project will investigate the - function of SP1 in cereals, and assess the potential of SP1 for manipulating plastids to improve cereal yield. I will generate transgenic plants with manipulated SP1 expression in Brachypodium distachyon (a versatile cereal model) and Oryza sativa - (rice). I will study the development of plastids in the transformants, and assess the transformants for beneficial effects on yield parameters, such as starch content, seed weight, germination, de-etiolation, leaf senescence and stress resistance. At - the end, I will have thoroughly assessed the potential use of SP1 for manipulating cereal traits linked to yield. A major strength of the proposal is the complementarity of my expertise with that of the host. Our unique combination of skills will - ensure success of the project. - - 2018-03-06, ongoing project - - - 2016-03-07 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - YIELDFACTOR - - - H2020-MSCA-IF-2014 - - - 659401 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 195 454,80 - - - Cambium genetics in Arabidopsis and Aspen: basic science meets wood production - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Multicellular organisms require an accurate coordination of multiple growth programs to develop. In plants, the lateral growth is the process by which stems and roots grow in diameter. Lateral growth is a pivotal process for - plant development that (i) provides the mechanical stability that plants need to expand their growth and sustain their structures and (ii) brings about large amounts of extremely useful plant biomass, especially in the form of wood in trees. Lateral - growth is mediated by a specialised group of stem cells collectively called cambium. Remarkably for such a crucial cell-type for plant development and biomass generation, very little is known about the genetic regulation of cambium. Dr. Agusti’s lab - has identified new strong potential cambium regulators through a novel approach that combines natural variation and Genome-Wide Association Studies (GWAS) in the model plant Arabidopsis thaliana. Based on the sophisticated skills that I acquired in - the field of tree genetics and genomics and on the large experience on genomics techniques held in the lab of Dr. Agusti, I present a project that will: - - 2017-08-31, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - WOODSofCHANGE - - - H2020-MSCA-IF-2014 - - - 655172 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 195 454,80 - - - Iridium Catalyzed Reductive Cyclization Cascades - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The aim of this fellowship is to develop new reductive cyclization cascades of lactams and amides that establish these feedstock chemicals as important chemical precursors to reactive iminium ions which can be intercepted by - pendant nucleophiles and exploited in carbon-carbon bond formation. A range of indole nucleophiles linked to amide and lactam functionality will be investigated for performance in the iridium catalyzed reductive cyclization cascades, and, based on - successful proof of concept studies already performed in the Dixon group, a range of semi-saturated nitrogen-containing polycyclic structures possessing one or more stereocentres distributed over an architecturally complex framework should result. As - well as studying diastereocontrol in the cascades, catalytic enantioselective variants will also be investigated. Finally, the application of the indole (spiro)cyclization reaction to the total synthesis of aspidospermidine will showcase the utility - of the developed chemistry. This multidisciplinary Fellowship, based on high-quality and novel research at the University of Oxford, one of the top-research centres worldwide, will complement Dr Xie’s skills and knowledge to improve his career - possibilities and at the same time, Dr Xie’s experience in creating catalytically active transition metal complexes will be critical for developing chiral versions of the iridium catalyst during the development of a catalytic asymmetric version of - the reductive cyclization cascade. - - 2018-07-10, ongoing project - - - 2016-07-11 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ICRED - - - H2020-MSCA-IF-2015 - - - 707559 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 183 454,80 - - - Regulation of (ADP-ribosyl)ation signalling in the DNA damage response: elucidating the function of a novel PARP1/ARTD1 interactor - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - (ADP-ribosyl)ation is a dynamic post-translational modification synthesised by PARPs/ARTDs and regulates a diverse array of cellular processes, including the DNA damage response (DDR). The last decade has significantly - improved our understanding of the key enzymes involved in (ADP-ribosyl)ation and the cellular pathways they function within. However, our understanding of how these enzymes are regulated is lacking and demands further investigation. In this proposal - I seek to redress this. - - 2018-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - PARPin - - - H2020-MSCA-IF-2015 - - - 701319 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 97 727,40 - - - Pathologies of temporality. Abnormal experiences of time in mental disorders - - - EUR 97 727,40 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The goal of the proposed research project is to analyze temporal disturbances in mental disorders and, as a result, to create a “map” of pathological experiences of time. The map will be phenomenological in nature, i.e. - cutting across existing classifications of mental disorders and avoiding untimely biological explanations. The project is highly interdisciplinary – it is situated at the intersection of phenomenology of temporality, philosophy of history and - phenomenology of mental illness. It continues the tradition of philosophical-psychiatric reflections on time in mental disorders that started a century ago and that concerned temporal disturbances in conditions such as: addictions, amnesia, anxiety, - dementia, depression, mania and schizophrenia. At the same time it enriches the existing empirical, clinical knowledge with non-medical interpretative schemes. The norm against which particular abnormalities will be assessed is going to be a - value-based model of the relationship between past, present and future, and not value-free, physicalist notion of temporality. The major contribution that the project is going to make is bridging the gap between studies in philosophical textual - analysis concerning temporality, which are theoretically sophisticated yet lack clinical references, and clinical papers, which will not serve its usual practical, medical function but pragmatically oriented philosophy. As a result, the study will - constitute a major step toward answering two highly relevant philosophical-medical questions. First, can pathologies of temporality be interpreted as disorders in themselves, and not as epiphenomena built upon primary mental illnesses, and therefore - provide ground for uniting otherwise separated categories of mental disorders? Second, how and to what extent can philosophical notions of time be applied not only to understanding of psychopathological phenomena but also to their treatment? - - 2017-08-31, closed project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - Pathologies - - - H2020-MSCA-IF-2014 - - - 659205 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 195 454,80 - - - Novel topological phases of matter: From topological invariants to experiments - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Topological phases are exotic states of quantum matter characterized by a topological invariant of their ground state that guarantees the existence of unusual surface or edge modes with many special properties. In the last - decade, the discovery of topological insulators has lead to a revolution in this field, in a remarkable joint effort between theory and experiment. Besides realizing a novel phase of matter, these materials can be exploited for many applications like - in spintronics, and can serve as a platform to realize even more exotic phases like topological superconductivity and Majorana fermions. In this project, we combine the input of very recent experimental breakthroughs with theoretical guidance to - propose realistic setups to characterize and manipulate these phases. - - - 2018-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - NovelTopo - - - H2020-MSCA-IF-2015 - - - 705968 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 183 454,80 - - - Functional magnetic resonance imaging of the cervical spinal cord at 7 Tesla - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Functional magnetic resonance imaging (fMRI) has become an indispensable tool in neuroscience to study human brain function non-invasively. However, translation of fMRI to investigate function of the second major component of - the central nervous system, the spinal cord, has been severely hampered by technical difficulties. Two major challenges for spinal fMRI relate to the anatomy: (i) severe static image distortion caused by vertebrae and the lungs and (ii) dynamic - signal instability introduced by breathing. I propose to address these problems by leveraging my expertise with cutting-edge technology for magnetic field compensation, available only to a few sites world-wide including my host institute in Oxford. - These advances will enable me to take advantage of the signal-to-noise ratio improvement of ultra-high field (7 Tesla) MRI scanners, which has been clearly demonstrated in the brain but has remained elusive for the spine. The final stage of this - project will deploy these methods on a collaborative project investigating the neurobiological mechanisms of pain in the spine. This project will enable me to build strategically on my dual training in engineering and medicine to develop an - inter-disciplinary research profile at the interface of neuroscience and methodology. - - 2017-08-31, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - Spinal cord fMRI - - - H2020-MSCA-IF-2014 - - - 659263 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 183 454,80 - - - Molecular mechanisms of arenavirus cell entry and antibody-mediated neutralization - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Over the last decades, multiple arenaviruses have emerged as zoonotic human pathogens. They cross the species barrier from their natural rodent hosts to humans and cause severe human disease. A key determinant of viral - zoonotic transmission is the ability to bind the receptor molecules displayed on the surface of the host cell. Despite the threat these viruses cause to public health, little is known of how they infect the host and how they are targeted by the - immune response. Furthermore, the treatment and prevention options are currently extremely limited. - - - 2017-04-30, closed project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ARENAVIRUS - - - H2020-MSCA-IF-2014 - - - 658363 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 195 454,80 - - - Quantitative characterization of cardiac tissue microstructure from Diffusion Tensor Imaging - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Cardiac Ventricular Remodelling (VR), i.e. the alteration of tissue microstructure that is a hallmark of several cardiac diseases, can have profound effects on cardiac function. A novel imaging technique, Diffusion Tensor - Imaging (DTI) offers the potential to quantify VR in vivo and could thus have a significant impact on the assessment and treatment of cardiac disease. This project proposes the development of advanced analytical tools to evaluate its usability in the - quantitative characterization of cardiac microstructure. The tools developed will aim at a) providing a mathematical description of normality in cardiac microstructure; and b) analysing local variation as an alternative descriptor for remodelling. A - combination of preclinical and clinical validation will be performed, with histological slices used as ground truth for the identification of microstructural features. Emphasis will be placed on the development and application of a rigorous - mathematical framework for the processing of tensor fields, including the quantification of local differences between tensors and the construction of statistical models for the quantification of pathology. - - 2017-08-31, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - DTI4micro - - - H2020-MSCA-IF-2014 - - - 655020 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 195 454,80 - - - Topological defects in nematic liquid crystals of active colloidal rods - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Active liquid crystals are out-of-equilibrium systems that display intriguing dynamic phenomena, arising from the interplay between topological defects and collective motion. Here, we propose to experimentally study for the - first time (i) the dynamics of topological defects in the active colloidal nematic phase and (ii) the interplay between these topological defects and collective dynamics, in three dimensions, at the single particle level, and with full control over - the defects. To reach these objectives, we first use a combination of advanced colloidal synthesis and surface modification techniques in order to develop a model system of active colloidal rods of controlled size, aspect ratio and surface - properties. We then confine this newly developed model system in microfluidic channels, where the colloidal rods form a nematic liquid crystal. Topological defects will be induced in the nematic phase using specific geometric constraints, which can - be varied to control the locations and strengths of the defects, or by optical trapping techniques. Finally, we use state-of-the-art confocal microscopy and sophisticated image analysis techniques to follow, in real time and 3D real space, both the - individual particle motion and the collective dynamics in the system. Our work will thus provide experimental verification of the intriguing link between topological defects and collective dynamics in active liquid crystals and inspire novel theories - and simulation codes capable of capturing the intrinsic complexity of coupling structure, orientation and activity. - - 2018-03-07, ongoing project - - - 2016-03-08 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - TOPACT - - - H2020-MSCA-IF-2015 - - - 705024 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 183 454,80 - - - Organocatalysis at the service of total synthesis: Madangamine alkaloids - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - This project will develop a new, highly enantioselective, state-of-the-art synthetic route to the madangamine alkaloids B, C and E based on a novel organocatalytic desymmetrization reaction as a key step, which will allow the - rapid and efficient construction of the BC rings ready for subsequent advancement to the majority of the family members. Evaluation of the anti-cancer biological activity of the different madangamines and late stage intermediates will be carried out. - This Fellowship project combines total synthesis, new asymmetric methodology development via organocatalysis and biological evaluation. It has been designed to augment and complement the research and transferable skills sets of the Marie Curie - fellow, and will greatly enhance his career prospects accordingly. Through the training and the research results arising, the Fellowship will be beneficial to the fellow, the host institution and European science. - - 2017-04-26, closed project - - - 2015-04-27 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ORSETOSY - - - H2020-MSCA-IF-2014 - - - 660125 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 195 454,80 - - - International mobility, local economics and European cooperation policies in the central Sahara - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Migration by nationals of sub-Saharan countries to the Sahara, often assimilated by African and European public institutions to departures to Europe, have, over the last decade, become the object of increased surveillance. The - European Union has put migration at the heart of its relations with Africa, and finances a broad range of programmes that aim at a better management of migration in the Sahara. Ranging from encouragement of legal reforms to assistance in the - repatriation of migrants, via equipping border posts with sophisticated means of control, EU interventions in the area take different forms, but they all have in common that little is known of their actual impact and side-effects on the ground. The - aim of this research project is to study the nature and practical results of European intervention in migration issues in the central Sahara, and its global cost, by combining an exhaustive analysis of European policies with empirical fieldwork, with - a view towards understanding and correcting the representations and assumptions that underpin them. - - - 2017-04-30, closed project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - MOLECOPS - - - H2020-MSCA-IF-2014 - - - 652755 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 195 454,80 - - - Following a path of breadcrumbs: How fish recognize landmarks during navigation - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Reliable vision-based object recognition is of fundamental importance to a wide range of species; however, it can be difficult as the appearance of an object can vary greatly as a result of changes in viewpoint. Recognition - during motion presents a particularly challenge as the appearance of an object continuously changes; a particular issue for animals that use landmarks to navigate. One recognition mechanism is to learn a two-dimensional snapshot of an object from a - set viewpoint. The object can later be recognized once the appearance of the object matches the stored snapshot. Some animals reduce the number of required snapshots by employing ‘active vision’, where they follow identical routes between landmarks. - For fish, the complexity of recognition is compounded by the fact that, unlike surface-bound animals, they can freely move vertically, which could potentially increase the number of approach views to an object. An alternate possibility is that fish - have a ‘view invariant’ recognition system and can generalize learned representations of objects so that they can be recognized from different viewing angles. However, high-level visual functions, such as object recognition, are associated with - complex mammalian brain structures and may be impossible for animals lacking similar neural circuitry. Despite these problems, we know that fish are capable of navigating efficiently using landmarks. The goal of this project is to investigate how - fish recognize visual landmarks during navigation and to determine how they cope with self-orientation related changes in the appearance of objects during motion. Using behavioural experiments, we will test whether fish have view invariant - recognition and/or if they employ active vision during navigation. The proposed project will further our knowledge of how fish perceive their visual environment as well as inform us about how conserved the mechanisms of object recognition are from an - evolutionary perspective. - - 2017-08-30, closed project - - - 2015-08-31 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - FISHNAV - - - H2020-MSCA-IF-2014 - - - 659684 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 195 454,80 - - - Relative Role of Reproductive Isolating Barriers During Speciation - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Understanding the appearance of reproductive isolation is essential for understanding mechanisms underlying the origin of species. This project aims at understanding the relative importance of different isolating barriers - during adaptive speciation by looking at patterns of genomic divergence. I will use numerical modelling, analysis of RNAseq data from several biotypes (incipient species) of a model organism (pea aphid), and will perform mating experiments to address - four research questions: - - 2018-03-10, ongoing project - - - 2016-03-11 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - IsoBar - - - H2020-MSCA-IF-2014 - - - 659847 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 183 454,80 - - - Utilizing the fusion machinery of Herpes Simplex Virus to unveil the general process of membrane fusion - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Membrane fusion is a basic cell biological process found in diverse pathways ranging from vesicle trafficking and cell division to viral host entry. It is mediated by fusion proteins residing in the membrane. The underlying - molecular mechanisms are supposed to follow a common order of events, i.e. fusion through hemifusion. Cell entry of Herpes simplex virus-1 (HSV-1) is enabled by glycoproteins residing on the viral envelope membrane. In contrast to other viruses, this - is accomplished by different glycoprotein species, mediating together the attachment and subsequent fusion between the viral and host cell membrane. At least four of these proteins are essential for membrane deformation leading to fusion pore - formation. In the here proposed project, I will take advantage of the modularity of the HSV-1 fusion machinery to dissect this process into discrete steps which I will analyse in situ at molecular resolution to determine the molecular details of - membrane fusion. To do so, I will employ a multidisciplinary approach combining methods and data from structural biology, biochemistry as well as biophysics and molecular dynamics to solve the mechanistic details of a cell biological question. This - includes fluorescence and cryo electron microscopy and tomography full-length membrane glycoprotein purification and biochemical reconstitution methods, biomolecular interaction and structural X-ray analysis, sub-volume averaging and classification - as well as single particle imaging. To find the nenecessary triggers for fusion I will reconstitute the complete fusion system and thereby reveal the spatio-temporal changes that catalyse the fusion process. Taken together this structure-functional - study will enable insights into hitherto ill-characterised intermediates in the conserved mechanism of membrane fusion. This project is a great opportunity to expand my research competence at the interphase of different fields ranging from cellular - and structural biology to biophysics. - - 2017-04-30, closed project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - KGBVIFEF - - - H2020-MSCA-IF-2014 - - - 654154 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 195 454,80 - - - Silicon/Carbon Nano-Hybrid Lithium-Ion Battery Anode: Green Facile Scalable Synthesis Inspired by Thermosetting Polymers - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The last two decades have witnessed a great commercial success of lithium ion battery (LIB) in portable electronic devices and electric vehicles. However, current LIB technology cannot meet the rapid increasing demand from - information technology and vehicle industry, primarily due to limited capacity and serious safety concern of graphite anode. Discovering new anode material with high capacity and good reliability has been a central issue. Because of its high - theoretical capacity and excellent operation safety, silicon (Si) has attracted considerable attention as a promising anode to replace graphite. Nevertheless, dramatic volumetric change during lithiation/delithiation process causes severe - pulverization and disconnection of electrode from current collector, leading to a fast capacity loss. To tackle these critical problems, a new concept to achieve facile, cost effective, green, and scalable synthesis of Si/carbon nanohybrid anode is - proposed. By reducing Si particle size to the range below 10 nm and homogeneous embedding of Si nanoparticles into carbon buffer matrix, the volume change and associated stress can be effectively accommodated to improve the cyclability of the LIBs. - Instead of conventional aqueous and/or organic solvents, three industrially widely used thermosetting resin monomer systems including vinyl ester resin, epoxy resin, and phenolic-formaldehyde resin are utilized as both solvent and carbon source. Cost - effective silane coupling agents bearing appropriate chemical functional groups act as the precursor of Si and cross-linking agents of the thermosetting polymers. Ultra small Si nanoparticles are in situ formed and homogeneously embedded in the in - situ formed porous carbon matrix by sequential photo/thermally induced polymerization, calcination in inert atmosphere, Magnesium thermal reduction, and KOH activation. The mechanism of control over morphology, crystallinity, dispersion, and - composition of the Si/C nanohybrid anode and correspondin - - 2017-09-13, closed project - - - 2015-09-14 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - LIB-Si anode - - - H2020-MSCA-IF-2014 - - - 655881 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 195 454,80 - - - Engineering Silicon Carbide Nanowires for Solar Fuels Production - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - By 2020, the European Union aims to reduce greenhouse gas emissions by 20-30% and increase renewable energy share to 20%. This scenario has imposed urgent needs to develop fossil fuel alternatives like solar fuels. In order to - produce solar fuels, the coupled reduction of CO2 and H2O is one of the most promising processes. However, the generation of efficient, stable and low-cost material for CO2/H2O reduction remains a big challenge. Silicon carbide nanowires (SiC NW) - exhibit the unique properties of large surface-to-volume ratio, tuneable transport properties and quantum size effects, which is very promising for the reduction of CO2/H2O to produce solar fuels. To date, the studies on SiC NW for CO2/H2O reduction - are limited due to the lack of (1) large-scale production techniques, (2) in situ characterization of the growth mode, and (3) there are no economical devices available for the evaluation of SiC NW. This project, SOLARFUELS, proposes the engineering - of SiC NW for solar fuels production through the development of a carbon nanotube template method for large-scale synthesis of SiC NW combing with in situ characterization of SiC NW during growth and post-mortem. Design of an economically viable - device is envisaged to exploit the in house generated SiC NWs. By introducing novel multiple sample holders for atmospheric gaseous reaction, the designed device can enable efficient catalyst/reactant contact along the vertically orientation of SiC - NW and reduce the cost for the device by at least a half.The SOLARFUELS is built across research areas of materials science, chemistry, chemical and device engineering. It perfectly integrates the Experienced Researcher (ER)’s skills in solar energy - application/device development and the Supervisor’s expertise in nanomaterials synthesis/characterization. It will play an important role in advancing ER's career for a permanent position and in addition it will contribute to new approaches to - further host's solar fuel research. - - 2017-08-27, closed project - - - 2015-08-28 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - Solarfuels - - - H2020-MSCA-IF-2014 - - - 654723 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 183 454,80 - - - The psychology of inequality: Understanding the social, cognitive and motivational foundations of people's attitudes towards the distribution of power and resources in society. - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The annual meeting of the World Economic Forum (WEF) in Davos, 2015, identified deepening inequality as the most pressing challenge facing the world. High inequality is liked to numerous social problems, as well as to greater - economic instability. Concern for these problems is not only restricted to highly educated, socio-political elites (e.g. the WEF). Large-scale surveys in several countries have shown that people generally have a preference for greater equality. - However, despite broadly shared egalitarian ideals, people often oppose policies aimed at reducing inequality and support policies that would have the opposite effect. I will call this the principle-implementation gap in attitudes towards inequality. - The primary aim of this project is to understand the reasons for this gap, by applying knowledge from social psychology to current work on inequality from the disciplines of economics, political science and sociology. In particular, I will test - whether similar social constraints, cognitive biases and psychological motives that explain other inconsistencies between peoples ideals and their attitudes, can also be used to explain this particular principle-implementation gap. I will draw on - methods used across the social sciences, including longitudinal and multilevel modelling of large-scale, cross-national survey data, and carefully controlled laboratory experiments. This multidisciplinary endeavour will provide insights to policy - makers, advocates and educators about how to communicate the problem of inequality to the general public in a way that maximises awareness and engagement. These insights will also be applicable to understanding what drives public opinion on other, - similarly complex issues of resource distribution that face modern societies (e.g. international trade). Thus, this project will shed light on how some of the biggest global issues of our time can be addressed through the democratic process. - - 2019-01-31, ongoing project - - - 2017-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - PINQ - - - H2020-MSCA-IF-2015 - - - 703316 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 195 454,80 - - - Comprehensive identification of host factors involved in the early steps of HIV infection. - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - 35 million people are currently infected with Human immunodeficiency virus (HIV), causative agent of AIDS. While cocktails of anti-retrovirals can reduce viral loading to undetectable levels, drug resistance can emerge due to - the high-mutation rate of the virus. Moreover, no cure is yet achieved. Therefore, it is crucial to explore complementary therapeutic strategies, a challenge that H2020 prioritizes in health. The strict dependency of HIV on host RNA-binding proteins - (RBPs) represents a potential step for intervention through host-based therapies, which can be more refractory to the evolution of resistance. In some sporadic cases, host RBPs have been shown to be incorporated into virions and impact downstream - early steps of infection. However, no global and systematic studies aimed to determine the scope and biological significance of host RBPs selectively packed with the HIV RNA within the virions have been reported so far. The main goal of this action, - referred to as hRBP-virion, is to address this important biological question by developing an unprecedented multidisciplinary approach that combines molecular biology and virology methods with next generation proteomics and data analysis. Hence, this - pioneer approach will open new avenues of research in the field of viruses that have major health and socioeconomic impact and will enhance world-class basic and applied European innovation. The hRBP-virion project requires an exclusive mix of - competences. I will bring research experience in RNA and molecular virology. My supervisor will train me in cutting-edge, system-wide proteomic methods. The host institution will provide state-of-the-art facilities and pooled expertise in a broad - range of disciplines. Together these will create an excellent and unique cross-disciplinary atmosphere that will ensure the successful outcome of hRBP-virion and the appropriate transfer of knowledge among the participants. - - 2019-05-02, ongoing project - - - 2017-05-03 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - hRBP-virion - - - H2020-MSCA-IF-2015 - - - 700184 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 183 454,80 - - - The Fall of a Colonial Legacy: A Modern History of Syrian Borders (1920-2015) - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - This project aims to propose a contemporary history of Syrian borders from their origins (1920) to the present day (2015). Upon the completion of my fellowship, my main objective will be to publish a fully documented and - innovative monograph on the history of the Syrian state by studying its emergence and consolidation, and by probing its colonial borders. As part of my research, I will rely on a multidisciplinary and comparative approach, using political science, - sociology and, more generally, border studies. My innovative methodology will require me to conduct dozens of semi-structured interviews and to examine Syrian, French & British archives. - - - 2018-10-09, ongoing project - - - 2016-10-10 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SYRIANBORDERS - - - H2020-MSCA-IF-2015 - - - 701923 - - - - - UNIVERSITA CA' FOSCARI VENEZIA - - - EUR 180 277,20 - - - Family, Power, Memory: Female Monasticism in Italy from 700 to 1100 - - - EUR 180 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - Recent history amply demonstrates the importance of religious belief as a fundamental historical force. In studying early medieval Europe, we see how crucial it has been in the creation of our own identity, underlying our - belief systems, cultural assumptions and core values, as well as our institutions. Modern history and anthropology help us pose questions of immediate concern on ethnicity and nationality, women and gender, identity and belief. I have engaged with - these issues previously, with a multidisciplinary mix of history, anthropology, art history and archaeology. This research project on Italian female monasteries from 700 to 1100 is also comparative and interdisciplinary. To understand medieval - society, it is essential to understand monasticism, and crucial to include Italy. I propose to bring together an integrated and broad-sweeping perspective by joining these together, and to approach the study of religious women as a laboratory for - exploring the complex relationship between gender and power. Royal or aristocratic monasteries have sources detailing the names, background and activities of nuns, representative of the political and ethnic composition of Italian society. To study - the evolution of nunneries makes it possible to trace changes in Italian political, social and cultural patterns, with the intermingling of family and politics. Understanding the tensions between early medieval Italian society’s male-controlled - political and religious power, and the influence of noble women as queens and nuns, is essential for grasping women’s ideological and spiritual power, and for recognizing the changing configurations of medieval Italy, a key factor for comprehending - some issues still at stake in Italian society today. Generally, a study of key mechanisms concerning the relationship between women, religious belief and behaviour, and politics and society can, through comprehending these in the past, illuminate key - aspects of modern European societies. - - 2017-09-30, closed project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - ITNUN - - - H2020-MSCA-IF-2014 - - - 654889 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 183 454,80 - - - Discovering the signalling pathways and physiology of active rhomboid proteases in the brain - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Proteases control major pathways in the nervous system and aberrant proteolysis underlies many neurobiological disorders and diseases e.g. Alzheimer's and Parkinson's disease. Signal generation and release is tightly regulated - by protease activity, as many key signalling factors are synthesised as transmembrane precursors that require cleavage to liberate their active ectodomains. The largest family of intramembrane proteases are the newly discovered rhomboids, which are - found in all kingdoms of life. To date, their physiological significance in mammals is largely unknown, as is the substrate-selectivity of most mammalian rhomboids. I have exciting preliminary data that two uncharacterised mammalian rhomboids, RHBDL1 - and RHBDL3, are specifically highly expressed in primary neurons in the CNS. Unlike the well-studied RHBDL2 and Drosophila rhomboids 1-3, they do not have activity against EGF-like growth factors, so they are likely to cleave a novel substrate. A - major limitation in protease research has been the lack of unbiased and systematic screens for their substrates. Addressing this deficiency, first, I aim to identify RHBDL1/3-dependent substrates in primary neurons, by adapting recently developed - biochemical assays, such as SPECS and BioID. My second aim is the mechanistic validation of these substrates. Third, I will be the first to study the physiological role for active rhomboids, using CRISPR-mediated knock-out neurons and mice. By - discovering the role and function of RHBDL1/3 in the brain, I will make an important contribution towards the elucidation of the physiological and medical significance of rhomboid proteases in mammals. - - 2017-04-06, closed project - - - 2015-04-07 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - NeuroRhomboid - - - H2020-MSCA-IF-2014 - - - 659166 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 1 758 846 - - - Chemical biology approaches to unraveling the histone code - - - EUR 1 758 846 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Posttranslational modifications on histones play crucial roles in the epigenetic regulation of eukaryotic gene expression. Chemical modifications that occur on histone tails include acetylation, methylation, phosphorylation, - ubiquitination, and SUMOylation. This chemical diversity together with the positions and combinations of these modifications give rise to complex networks of highly controlled gene expression programs. The identification and characterisation of - chromatin-associated proteins (or epigenetic regulators) in recent years has advanced our understanding of the significance of these histone modifications and the regulatory outcomes in development and in disease. - - - 2021-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - EPITOOLS - - - ERC-2015-STG - - - 679479 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 183 454,80 - - - Incorporation of unnatural fluorinated amino acids to probe the function of the bacterial efflux system Kef in a cellular setting. - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The potassium efflux system, Kef, protects bacteria against the detrimental effects of electrophilic compounds via acidification of the cytoplasm. Its vital role in maintaining cell homeostasis makes Kef a promising target for - antibiotics, but such drugs can be developed only with a molecular understanding of Kef activation. Our work indicates that phenylalanine residue 441 (F441) in Escherichia coli is crucial for the activation of K+ efflux. This mechanism is conserved, - and F448 of Shewanella denitrificans Kef (SdKef) has the same function. This work employed X-ray crystallographic studies using a truncated construct of the E. coli Kef soluble C-terminal domain (EcKefCTD) and biophysical studies conducted on the - SdKef C-terminal domain (SdKefCTD). While the crystallographic studies have been essential in hypothesis generation, they lack the dynamic aspect that is required to understand the mechanism of Kef activation. Although the use of a truncated - construct has allowed development of biophysical assays, we wish to extend our work to focus on the full-length channel. To achieve these aims we will employ whole cell 19F NMR to probe the function of Kef. - - 2017-09-30, closed project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - FLUOROKEF - - - H2020-MSCA-IF-2014 - - - 660156 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 97 727,40 - - - CULTURAL POLICY AND CHORAL-HISTORICAL IDENTITY IN THE CHORAL/MUSICAL LIFEOF OXFORD UNIVERSITY COLLEGES AND HALLS IN THE 21ST CENTURY - - - EUR 97 727,40 - - - United Kingdom - - - Higher or Secondary Education Establishments - - This project presents an interdisciplinary study on the collective identities and (sometimes contested) cultures of collegiate choirs at University of Oxford (UOXF) and focuses on cultural-political issues and challenges - facing the choral/musical tradition in UOXF colleges and halls in the 21st century. This project refers to extra-curricular music activities in the academic context, which relate to the current European Agenda for culture (accessible and inclusive - culture and cultural heritage as well as referring to current societal challenges in Europe (social inclusion) whereas the project deals with musical activities in a somewhat elitist community. Drawing predominantly on the Sociology and Psychology of - Music, as well as the contemporary history of Music and Cultural Policy, this interdisciplinary study can be divided into two main strands of research: A) Firstly from the perspective of students; to map the demographical background and social - structures of members of the collegiate choirs and how the historical tradition affects and shapes the collective identities and individual cultures of the choirs. B) Secondly from the perspectives of staff/administrators; to study the - cultural-political issues in ‘governmental’ decision making regarding the future of the collegiate choirs in terms of perspectives like politics of admission, competition for musical talent, forms of musical direction, gender perspectives, financial - distribution and inequalities, musical hierarchies and the possible impact of cuts in public funding to musical school activities in general. - - 2017-08-31, closed project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - OXFORDCHOIRS - - - H2020-MSCA-IF-2015 - - - 707827 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 195 454,80 - - - Studying Interfacial Dynamics by Interferometric Scattering - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - We propose to apply a cutting-edge optical microscopy based on interferometric scattering microscopy (iSCAT) to directly study the dynamics of the fundamental system of nanoparticles at fluid interfaces. Nanoparticles at - interfaces are a central research topic in colloidal science. They have various technological applications, related to, for example, emulsification, optical devices, and chemical catalysis. In addition, nanoparticles at interfaces make an ideal - experimental model system for investigating topics in condensed matter physics, such as the dynamics of partially confined fluids and the phase behavior of 2D fluids. While many experimental studies have characterized the self-assembly, structure, - and motion of such particles, important questions relating to adsorption/desorption dynamics and inertial effects, remain unanswered due to technical limitations of temporal and spatial resolution. iSCAT offers exclusive accessibility to answer these - questions, through unprecedented capabilities of nanoparticle tracking in three dimensions with simultaneous nanometre spatial and microsecond temporal precision. Specifically, we aim at achieving two objectives for the first time; (i) observing and - quantifying inertial effects at fluid-fluid interfaces, and (ii) characterizing the three-dimensional interfacial behavior of nanoparticles at interfaces. Overall, these objectives aim at expanding and generalising interfacial microrheology to much - shorter time-scales, as well as to provide critical insight to the mechanisms underlying particle stability and self-assembly at interfaces. - - 2018-05-31, ongoing project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - INTFACDYN - - - H2020-MSCA-IF-2015 - - - 706461 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 1 361 077 - - - Geometry and Anomalous Dynamic Growth of Elastic instabiliTies - - - EUR 1 361 077 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Elastic instabilities are ubiquitous, from the wrinkles that form on skin to the ‘snap-through’ of an umbrella on a windy day. The complex patterns such instabilities make, and the great speed with which they develop, have led - to a host of technological and scientific applications. However, recent experiments have revealed significant gaps in our theoretical understanding of such instabilities, particularly in the roles played by geometry and dynamics. I will establish a - group to develop and validate a theoretical framework within which these results can be understood. Central to my approach is an appreciation of the crucial role of geometry in the pattern formation and dynamics of elastic instabilities. - - 2020-03-31, ongoing project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - GADGET - - - ERC-2014-STG - - - 637334 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 183 454,80 - - - Assessment of Global and Regional Cardiac Functional Improvements in a Murine Model of Myocardial Infarction following Stem Cell Treatments - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Cardiosphere-derived stem cell (CDC) therapy for myocardial infarction (MI) has been shown to elicit moderate beneficial effects. Research currently focuses on improving CDC administration, retention and efficacy. This - proposal aims to develop Magnetic Resonance Imaging (MRI) and engineering tools to facilitate this research. Specifically, microinjection of fluorine-19 labeled CDCs will allow for MRI tracking and quantification in vivo. Non-invasive global and - regional cardiac function measurements will assess efficacy of stem cell (SC) therapy. Parallel to these studies will be an independent design, synthesis, use and evaluation of fiber-enriched scaffold. The anticipated impact will be multifaceted, - including the study of cardiac function in disease, and the potential applicability of generated results with cutting edge SC regenerative technologies in heart failure and prominent cardiomyopathies. Research efforts will be stimulated in - manufacturing processes for scaffolds, cardiac functional assessment post-injection of SCs, and validation of their homing, engraftment and viability using cellular tracking methods. - - 2017-06-30, closed project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - STEMCELLTRACK - - - H2020-MSCA-IF-2014 - - - 652986 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 1 499 911 - - - Online Labour: The Construction of Labour Markets, Institutions and Movements on the Internet - - - EUR 1 499 911 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - "World Bank, EC Joint Research Centre, and other bodies have recently highlighted the potential of online labour markets to boost employment and economic growth. While national job markets have stagnated, online labour markets - that connect firms with knowledge and service workers around the world have grown up to 60% a year. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - iLABOUR - - - ERC-2014-STG - - - 639652 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 168 166,90 - - - Probabilistic Argumentation on the Web - - - EUR 168 166,90 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The (World Wide) Web hosts a wide range of argumentative text from resources of multiple disciplines and online debates. Also, tools (such as Debadepedia and Twitter) encourage the communication of arguments in social and - scientific settings. With the exponential growth of the Web and its users, a vast amount of argumentative text on the Web remains hidden. In order to query the Web for structured arguments included in web pages, it is necessary to address both of the - following issues: (1) the deployment of technologies that enable an automatic extraction of the components of natural language arguments and the representation of their meaning and (2) the deployment of a pragmatic argumentation formalism that takes - into account the uncertain and inconsistent nature of data on the Web to reason with structured arguments. - - - 2017-12-31, closed project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - United Kingdom - - - ARGUE_WEB - - - H2020-MSCA-IF-2015 - - - 707407 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 1 727 456 - - - Molecular analysis of the Hedgehog signal transduction complex in the primary cilium - - - EUR 1 727 456 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The unexpected connection between the primary cilium and cell-to-cell signalling is one of the most exciting discoveries in cell and developmental biology in the last decade. In particular, the Hedgehog (Hh) pathway relies on - the primary cilium to fulfil its fundamental functions in orchestrating vertebrate development. This microtubule-based antenna, up to 5 µm long, protrudes from the plasma membrane of almost every human cell and is the essential compartment for the - entire Hh signalling cascade. All its molecular components, from the most upstream transmembrane Hh receptor down to the ultimate transcription factors, are dynamically localised and enriched in the primary cilium. The aim of this proposal, which - combines structural biology and live cell imaging, is to understand the function and signalling consequences of the multivalent interactions between Hh signal transducer proteins as well as their spatial and temporal regulation in the primary cilium. - The key questions my laboratory will address are: What are the rules for assembly of Hh signal transduction complexes? How dynamic are these complexes in size and organisation? How are these processes linked to the transport and accumulation in the - primary cilium? - - 2020-07-31, ongoing project - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - CilDyn - - - ERC-2014-CoG - - - 647278 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 1 929 306 - - - Cities in Global Financial Networks: Financial and Business Services and Developmentin the 21st Century - - - EUR 1 929 306 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Financial and business services (FABS), including law, accounting, and business consulting, have been one of the most dynamic sectors of the world economy, with a fivefold rise in real value added since 1980. Although FABS are - central to the processes of globalisation, financialisation, urbanisation and development, our understanding of the sector in the context of tumultuous changes of the early 21st century is partial. How have the FABS firms and centres been affected by - the global financial crisis and the Eurozone crisis? How are they changing in response to new financial regulation, the expected shift of economic activity to the Asia-Pacific region, and the digital revolution? What are the impacts of FABS on urban, - regional, and global development? We urgently need groundbreaking frontier research to better understand the nature and dynamics of FABS, and their implications. - - 2021-07-31, ongoing project - - - 2016-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - CityNet - - - ERC-2015-CoG - - - 681337 - - - - - UNIVERSITY OF LONDON - UNIVERSITY OF LONDON - CITY UNIVERSITY OF LONDON - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 1 955 270 - - - Metacognition of Concepts - - - EUR 1 955 270 - - - United Kingdom - United Kingdom - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project will investigate the thoughts and feelings that accompany the use of concepts. Concepts lie at the heart of the extraordinary power of the human mind. They are the building blocks of thought, the tools with which - we think. Like physical tools, they can be more or less dependable, more or less fit for purpose: e.g. for most people GENE feels like a better concept than MEME. We have an intuitive sense of how dependable a concept is, which is crucial when we - decide whether to rely on the concept. It can underpin our decision to reject some concepts (e.g. RACE) and embrace others in our theorising (e.g SPECIES). Similarly in everyday thinking: when concepts are selected for reasoning and induction, and - when different cognitive processes compete for control of action, the metacognition that accompanies the concepts involved will have a powerful effect. However, metacognition directed at concepts is still poorly understood. We lack even a clear - theoretical framework to underpin research in this area. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - MetCogCon - - - ERC-2015-CoG - - - 681422 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 1 497 422 - - - Low-dimensional topology in Oxford - - - EUR 1 497 422 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project aims to build a group that brings together experts in gauge-theoretic, geometric, and group-theoretic techniques. It consists of 4 branches. - - - 2021-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - OXTOP - - - ERC-2015-STG - - - 674978 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 1 499 496 - - - Terrestrial vertebrates and the evolutionary origins of morphological diversity - - - EUR 1 499 496 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Explaining the great disparity of organismal form is a central goal of biological research. However, despite many decades of inquiry, there is little understanding of how evolution gave rise to this disparity. Key hypotheses - predict changes in macroevolutionary modes through geological time: rates of evolution may either have decreased as global niche space became crowded, or increased due to accumulation of key innovations that improve body plan versatility. The absence - of data to test these hypotheses a major knowledge gap that severely limits our understanding of evolution on Earth. - - 2021-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - TEMPO - - - ERC-2015-STG - - - 677774 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 195 454,80 - - - Enantioselective Synthesis of Madangamine Alkaloids via Organocatalytic Desymmetrization - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - This project will develop a new, highly enantioselective, state-of-the-art synthetic route to madangamine alkaloids B, C and E based on a novel organocatalytic desymmetrization reaction as a key step, which will allow the - rapid and efficient construction of the AC rings ready for subsequent advancement to the majority of the family members. Evaluation of the anti-cancer biological activity of the different madangamines and late stage intermediates will be carried out. - This Fellowship project combines total synthesis, new asymmetric methodology development via organocatalysis and biological evaluation. This multidisciplinary Fellowship, based on high-quality and novel research at the University of Oxford, one of - the top-research centres worldwide, has been designed to augment and complement Dr Vasu’s skills and knowledge to improve his career possibilities and, at the same time, Dr Vasu’s experience in new methodology development and catalysed - transformations will be advantageous to the design of the organocatalyst in the key step of the synthesis. The Fellowship will also be useful to establish new collaboration opportunities for the Dixon group. Through the training and the research - results arising, the Fellowship will be beneficial to the fellow, the host institution and European science. - - 2018-08-15, ongoing project - - - 2016-08-16 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ESOMAVOD - - - H2020-MSCA-IF-2015 - - - 703789 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 2 492 266 - - - Vision-based Guidance and Control in Birds, with Applications to Autonomous Unmanned Aircraft - - - EUR 2 492 266 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Birds have been called “une aile guidée par un oeil”, and whilst they possess many senses besides vision, their wings are indeed guided largely by their eyes. Nevertheless, we know surprisingly little of how birds use vision - to guide their flight, and almost nothing of the underlying guidance and control laws. This is an extraordinary omission, and unfortunate given the importance that vision is poised to assume in autonomous unmanned aircraft. With good reason, the law - still requires a human eye to remain in the loop, but as with the coming revolution in driverless cars, the future of flight lies in autonomy. I see a once-in-a-career opportunity here: we need only imagine a hawk, shooting over the top of a hedgerow - then plunging through the undergrowth onto its fleeting prey, to see what engineering could learn. Building upon the success of my ERC Starting Grant on Bird and Insect Flight Dynamics and Control, my proposed Consolidator Grant has two overarching - ambitions: 1) to revolutionize our understanding of vision-based guidance and control in birds; and 2) to carry these insights over to application in unmanned autonomous aircraft. This presents a formidable technical challenge, but by combining a - state-of-the-art motion capture suite with targets/obstacles moving under motion control in a custom-built facility, I will use system identification techniques to unambiguously identify the guidance and control laws underpinning perching, pursuit, - obstacle avoidance, and gap negotiation in birds. More than this, I will identify the precise motion cues to which they attend, settling longstanding questions on the extent to which guidance emerges from simple algorithmic rules versus state - feedback and estimation, with wider implications for our understanding of avian perception. This work will break new ground in all directions, testing applied insights in the same facility, and so leading the world in drawing the study of birds and - aircraft together under one roof. - - 2021-07-31, ongoing project - - - 2016-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - HawkEye - - - ERC-2015-CoG - - - 682501 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 1 106 719 - - - Randomness and pseudorandomness in discrete mathematics - - - EUR 1 106 719 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Discrete mathematics has seen enormous advances in the last few years, with solutions being found to a number of famous and long-standing questions, such as the Erdos distinct distance problem and the existence conjecture for - combinatorial designs. Much of this progress owes to an increased understanding of random and pseudorandom objects. An entire framework, known as the probabilistic method, has grown around the application of randomness to combinatorial problems, - while pseudorandomness is playing an increasingly important role. - - 2021-06-30, ongoing project - - - 2016-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - RanDM - - - ERC-2015-STG - - - 676632 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 1 902 598 - - - Family size matters: How low fertility affects the (re)production of social inequalities - - - EUR 1 902 598 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This is the first comprehensive study on the consequences of low fertility for the (re)production of social inequalities. Inequalities in socio-economic well-being, including gender inequalities and regional inequalities, are - reproduced from generation to generation. The family plays a central role in the reproduction of social inequalities. Over the last 5 decades, most societies in Europe and East-Asia moved or started moving towards low fertility regimes where the - majority of women bear 0, 1 or 2 children. What does this radical change in family size imply for the (re)production of social inequalities? - - - 2021-06-30, ongoing project - - - 2016-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - FAMSIZEMATTERS - - - ERC-2015-CoG - - - 681546 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 1 980 112 - - - Computational Propaganda:Investigating the Impact of Algorithms and Bots on Political Discourse in Europe - - - EUR 1 980 112 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Social media can have an impressive impact on civic engagement and political discourse. Yet increasingly we find political actors using digital media and automated scripts for social control. Computational propaganda—through - bots, botnets, and algorithms—has become one of the most concerning impacts of technology innovation. Unfortunately, bot identification and impact analysis are among the most difficult research challenges facing the social and computer sciences. - - 2020-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - COMPROP - - - ERC-2014-CoG - - - 648311 - - - - - UNIVERSITA COMMERCIALE LUIGI BOCCONI - UNIVERSITA COMMERCIALE LUIGI BOCCONI - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 2 400 555 - - - Discontinuities in Household and Family Formation - - - EUR 2 400 555 - - - Italy - Italy - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Household, family and fertility changes are key drivers of population dynamics. Discovering and explaining the velocity of these changes is essential to understand the current situation and to provide scientific evidence on - our demographic future. DisCont will provide seminal contributions by studying the impact of macro-level discontinuities on household and family formation (including fertility) in post-industrial contemporary societies. In the past decade, two - macro-level discontinuities have radically transformed lives: the Great Recession and the digitalization of life and of the life course. Although their short-term and long-term impacts are likely to be fundamental, they have not yet been - systematically analysed. Through a coordinated series of theoretically-founded empirical studies based on linked macro- and micro-level data, and using a comparative perspective, DisCont will argue that macro-level discontinuities are crucial in - explaining broad changes in household and family formation, and that their effects can be persistent either for the population as a whole, or for specific cohorts. DisCont will contribute to five areas: 1) it will make theoretical advances by showing - the importance of macro-level discontinuities in the explanation of changes in household and family formation in particular, and in population dynamics in general; 2) it will substantially advance our knowledge of household and family formation in - post-industrial contemporary societies; 3) it will contribute in a systematic and path-breaking way to research on the broader societal impact of digitalization and of the Great Recession; 4) it will bring a paradigm shift in Age-Period-Cohort - modelling; 5) it will make ground-breaking contributions on the demographic use of “big data” and on the use of agent-based models for the population-level implications of household and family change. - - 2022-01-31, ongoing project - - - 2017-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Italy - - - DisCont - - - ERC-2015-AdG - - - 694262 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - UNIVERSITEIT UTRECHT - - - EUR 2 186 400 - - - Music and Late Medieval European Court Cultures: Towards a Trans-Disciplinary and Post-National Cultural Poetics of the Performative Arts - - - EUR 2 186 400 - - - United Kingdom - United Kingdom - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Late medieval European court cultures have traditionally been studied from a mono-disciplinary and national(ist) perspective. This focus has obscured much of the interplay of cultural performances that informed “courtly life”. - Recent research has begun to reverse this, focusing on issues such as the tensions between orality, writing, and performance; the sociocultural dimensions of making and owning manuscripts (musical and otherwise); the interstices between musical, - literary and visual texts and political, social and religious rituals; and the impact of gender, kinship, and social status on the genesis and transmission of culture and music. These “new medievalist” studies have significantly enhanced our - understanding of the cultural meanings of singing, listening, and sound in late medieval times. - - - 2020-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - MALMECC - - - ERC-2014-ADG - - - 669190 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 2 605 261 - - - Resolving Morpho-Phonological Alternation: Historical, Neurolinguistic, and Computational Approaches - - - EUR 2 605 261 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In morpho-phonological alternations the shapes of morphemes differ between morphologically related word forms. In these alternations the morphological environment is also implicated (revére ~ réverence verb [iː] ~ noun [ɛ] and - stress differ) unlike alternations which are conditioned only by the phonological environment. - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - MOR-PHON - - - ERC-2015-AdG - - - 695481 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 1 438 846 - - - Dynamic Earth Evolution and Paleogeography through Tomographic Imaging of the Mantle - - - EUR 1 438 846 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - DEEP TIME will unearth a record of geological time that is buried thousands of kilometres deep. The seafloor that covers two-thirds of the earth's surface is a tiny fraction of all seafloor created during its history – the - rest has sunk back into the viscous mantle. Slabs of subducted seafloor carry a record of surface history: how continents and oceans were configured over time and where their tectonic plate boundaries lay. DEEP TIME will follow former surface oceans - as far back in time as the convecting mantle system will permit, by imaging subducted slabs down to the core with cutting-edge seismological techniques. Current tectonic plate reconstructions incorporate little if any of this deep structural - information, which probably reaches back 300+ million years; they are based on present-day seafloor, which constrains only the past 100-150 million years. - - 2020-07-31, ongoing project - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - DEEP TIME - - - ERC-2014-STG - - - 639003 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 1 999 416 - - - Discovering how polycomb domains form and function in gene regulation - - - EUR 1 999 416 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Polycomb group chromatin modifying systems are essential for normal gene regulation and development, and alterations in their activity are a hallmark of a broad range of cancers. Although the chromatin modifications placed by - the two central polycomb protein complexes (PRC1 and PRC2) are well-characterized, how this fascinating system selects its target sites in vivo, and then forms polycomb chromatin domains that are repressive to transcription remains enigmatic. This - constitutes the major conceptual gap in our understanding of this essential gene regulatory system. We recently discovered a new pathway that is sufficient in model systems to initiate polycomb chromatin domain formation. Building on this discovery, - an ambitious high-risk/high-reward yet hypothesis-driven multidisciplinary approach integrating biochemical, molecular, genomic, and single-cell analyses will be exploited to discover the fundamental principles that underpin polycomb domain formation - and subsequently transcriptional repression. Specifically, the three aims of the research programme are to: (i) Discover how the KDM2B/PRC1 complex initiates polycomb domain formation, (ii) Discover how polycomb target sites are selected and polycomb - domains formed during normal cell lineage commitment, and (iii) Discover how polycomb domains regulate gene expression. Going well beyond the state-of-the-art, our innovative approaches will lead to major new breakthroughs closing the conceptual gap - that currently limits our understanding of how polycomb complexes regulate gene expression, an essential first step towards the possibility of devising strategies for therapeutic intervention in human cancers and other diseases where these systems - are perturbed. Furthermore, support from the ERC in tackling these important problems will allow me to recruit the talented individuals necessary to achieve our objectives and consolidate my position as an emerging leader in the field. - - 2021-05-31, ongoing project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - PolyDomFormFuncReg - - - ERC-2015-CoG - - - 681440 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 195 454,80 - - - The Colours of the Past in Victorian England - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - This project entitled “The Colours of the Past in Victorian England” (COPAST) aims to analyse the reception of the chromatic material culture of Antiquity and the Middle Ages in the works of writers and painters from William - Morris’s close circle. These politically-committed poets and artists looked towards the ideologically-charged colours of Hellenic and medieval arts and crafts, in order to retrieve and emulate supposedly more meaningful hues and dyeing processes - which they believed modern science and economic imperatives had stripped of their symbolic and artistic value. The Victorian age (1837-1901) was indeed a turning point in terms of scientific discoveries of new chemical colours, including coal-tar - based synthetic dyes. Dr. Ribeyrol will investigate ideological approaches to ancient polychromy in the context of the Greek and Gothic Revivals which affected industrialized England in the second half of the 19th century. Using close analysis of art - works, literary texts and pigment recipe books, she will contrast these ancient hues with the new chemical aniline dyes which were mainly devised for the expanding textile industry. This innovative focus on chromatic materiality in the field of - Victorian art history and literature will enable her to shed light on the artistic impact of this colour revolution which radically unsettled the way certain avant-garde Victorian writers and artists related to chromatic terminology and used - traditional, organic pigments. - - 2018-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - COPAST - - - H2020-MSCA-IF-2014 - - - 655396 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 1 482 363 - - - Characterising the Gene Regulatory Networks Governing Photosynthesis: From Basic Understanding to Targeted Engineering - - - EUR 1 482 363 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Photosynthesis underpins life on earth. Despite its fundamental importance, our knowledge of the molecular regulators that control the expression of photosynthetic genes is limited, and only four transcription factors are - known to regulate the expression of cohorts of photosynthetic genes in plants. - - - 2020-10-31, ongoing project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - PHOTONET-C4 - - - ERC-2014-STG - - - 637765 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 2 863 366 - - - Large Scale Structure Constraints of General Relativity - - - EUR 2 863 366 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The past decade has witnessed a phenomenal success in relativistic cosmology. It is now possible to constrain the structure, content and evolution of the Universe with an accuracy of a few percent. The current focus of - cosmology is to understand some of the fundamental problems in physics such as: the accelerated expansion of the universe, the nature of dark energy and dark matter and the initial conditions of large scale structure. Key to addressing these problems - is ascertaining the role general relativity plays in cosmology. While we now have remarkable astrophysical constraints on general relativity on milliparsec scales, we have no direct cosmological constraints on gigaparsec scales. Given the quality of - the up and coming cosmological data, it is now time to tackle the challenge of constraining general relativity on large scales. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - GravityLS - - - ERC-2015-AdG - - - 693024 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 3 234 789 - - - Adaptive Optical Microscopy Systems: Unifying theory, practice and applications - - - EUR 3 234 789 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Recent technological advances in optical microscopy have vastly broadened the possibilities for applications in the biomedical sciences. Fluorescence microscopy is the central tool for investigation of molecular structures and - dynamics that take place in the cellular and tissue environment. Coupled with progress in labeling methods, these microscopes permit observation of biological structures and processes with unprecedented sensitivity and resolution. This work has been - enabled by the engineering development of diverse optical systems that provide different capabilities for the imaging toolkit. All such methods rely upon high fidelity optics to provide optimal resolution and efficiency, but they all suffer from - aberrations caused by refractive index variations within the specimen. It is widely accepted that in many applications this fundamental problem prevents optimum operation and limits capability. Adaptive optics (AO) has been introduced to overcome - these limitations by correcting aberrations and a range of demonstrations has shown clearly its potential. Indeed, it shows great promise to improve virtually all types of research or commercial microscopes, but significant challenges must still be - met before AO can be widely implemented in routine imaging. Current advances are being made through development of bespoke AO solutions to individual imaging tasks. However, the diversity of microscopy methods means that individual solutions are - often not translatable to other systems. This proposal is directed towards the creation of theoretical and practical frameworks that tie together AO concepts and provide a suite of scientific tools with broad application. This will be achieved - through a systems approach that encompasses theoretical modelling, optical engineering and the requirements of biological applications. Additional outputs will include practical designs, operating protocols and software algorithms that will support - next generation AO microscope systems. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - AdOMiS - - - ERC-2015-AdG - - - 695140 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 1 312 383 - - - New Approaches to the Identification of Macroeconomic Models - - - EUR 1 312 383 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Macroeconomic data are largely non-experimental. Thus, causal inference in macroeconomics is largely based on assumptions about what aspects of the variation in the data are exogenous. This presents two major challenges, which - this research addresses directly. First, few such assumptions are generally accepted. Second, conditional on any set of assumptions, identification of causal effects is often weak because there is little relevant variation in the data. To tackle - these challenges, I propose three lines of enquiry to explore new sources of identification and develop the requisite econometric methods. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - Macro Identification - - - ERC-2014-CoG - - - 647152 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 2 350 533 - - - Monumental Art of the Christian and Early Islamic East: Cultural Identities and Classical Heritage - - - EUR 2 350 533 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project will analyse the monumental art (large decorative programmes on buildings) of two areas of the former eastern Roman Empire which came under Islamic rule but which have never been the subject of an integrated - comprehensive study: Egypt and Syro-Palestine (modern Syria, Jordan, Lebanon, and Israel/Palestine). It aims to determine systematically how the strength and nature of the local ‘classical’ (Greco-Roman) traditions and expressions of identities - influenced monumental art in these regions during Late Antiquity (AD 250–750), the period of transition from paganism to Christianity and, in turn, to Islam. By defining and distinguishing between the different strands of classical influence, both - local and external (from the centres of Rome, Constantinople, and Alexandria), and investigating the roles of local artists and artisans as creators rather than imitators, this project will transform our understanding of the artistic culture of the - late antique Middle East. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - HERITAGE - - - ERC-2015-AdG - - - 694105 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 1 706 729 - - - Combinatorial Construction - - - EUR 1 706 729 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Combinatorial Construction is a mathematical challenge with many applications. Examples include the construction of networks that are very sparse but highly connected, or codes that can correct many transmission errors with - little overhead in communication costs. For a general class of combinatorial objects, and some desirable property, the fundamental question in Combinatorial Construction is to demonstrate the existence of an object with the property, preferably via - an explicit algorithmic construction. Thus it is ubiquitous in Computer Science, including applications to expanders, sorting networks, distributed communication, data storage, codes, cryptography and derandomisation. In popular culture it appears as - the unsolved "lottery problem" of determining the minimum number of tickets that guarantee a prize. In a recent preprint I prove the Existence Conjecture for combinatorial designs, via a new method of Randomised Algebraic Constructions; this result - has already attracted considerable attention in the mathematical community. The significance is not only in the solution of a problem posed by Steiner in 1852, but also in the discovery of a powerful new method, that promises to have many further - applications in Combinatorics, and more widely in Mathematics and Theoretical Computer Science. I am now poised to resolve many other problems of combinatorial construction. - - 2020-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - CC - - - ERC-2014-CoG - - - 647678 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 1 492 828 - - - External Control of Liquid Nanofilms for Switchable Friction and Adhesion - - - EUR 1 492 828 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The overall vision of the project is to demonstrate methods for switching friction and adhesion – such as “switch off friction” or “switch on adhesion” – reversibly and with remote control. My hypothesis is that fluids - confined to nanofilms between solid objects can be designed to dramatically alter their surface properties under the influence of applied fields, and so can be used to switch friction, lubrication or adhesion in a controlled and reversible way. The - emphasis of the project is on creating well-defined model experiments, with high resolution in both film thickness and interaction forces, in order to reach a fundamental understanding of the new concepts and mechanisms involved. The novelty lies in - both the newly-proposed mechanisms of switching friction and adhesion interactions, and the new instrumentation constructed to detect and analyse the forces. The new methodologies necessary for these pioneering experiments involve two new versions of - a Surface Force Balance (SFB) providing molecular-resolution (0.1nm) control and measurement of interfacial liquid films, controlled application of electric and magnetic fields, and ultra-sensitive measurement of friction and adhesion. Notably, one - of these new instruments will have macroscopic graphene electrodes for confinement of liquid nanofilms (0 – 100nm) between atomically smooth electrodes. The wide range of ‘switchable’ liquids studied will include polyelectrolytes, magnetic fluids, - ionic liquids and self-assembled systems. Ultimately, this project will change the way we think about surface interactions into something we can ‘switch and control’. - - 2021-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - LIQUISWITCH - - - ERC-2015-STG - - - 676861 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 2 497 907 - - - CEREBRAL ASYMMETRY: NEW DIRECTIONS IN CORRELATES AND ETIOLOGY - - - EUR 2 497 907 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - "150 years after Broca's seminal statement "Nous parlons avec l'hémisphère gauche" we still do not know how or why we have this bias. I propose that by studying cases of impaired language development and combining genetic and - neuropsychological approaches we will be able to make a leap forward in our understanding of the quintessentially human characteristic of functional cerebral asymmetry. I argue that contradictory findings in the literature may be reconciled if we - adopt a novel approach to cerebral asymmetry. In particular, I propose a network efficiency hypothesis which maintains that optimal development depends on organisation of key language functions within the same cerebral hemisphere. - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - CANDICE - - - ERC-2015-AdG - - - 694189 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 2 278 073 - - - Autocatalysis: A bottom-up approach to understanding the origins of life - - - EUR 2 278 073 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - "The origin of life is not well understood, and is one of the great remaining questions in science. Autocatalytic chemical reactions have been extensively studied with the aim of providing insight into the principles - underlying living systems. In biology, organisms can be thought of as imperfect self-replicators, which produce closely related species, allowing for selection and evolution. Autocatalysis is also an important part of many other biological processes. - - - 2021-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - Autocat - - - ERC-2015-CoG - - - 681491 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 1 499 985 - - - Stories of Survival: Recovering the Connected Histories of Eastern Christianity in the Early Modern World - - - EUR 1 499 985 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - From Lebanese immigrants in Argentina to Iraqi refugees in Sweden, Eastern Christians can be found today scattered across the entire world. Too often, however, this global migration has been seen purely as a modern - development, one arising from contemporary political and confessional events in the Middle East, while in fact this phenomenon had its roots in the early modern period. From the sixteenth century onwards, Christians from the Ottoman Empire set out - for distant worlds and foreign lands, travelling as far as Europe, India, Russia, and even the Americas and leaving traces of themselves across countless European and Middle Eastern archives, chanceries, and libraries. This transnational, - ground-breaking project will gather all of these disparate sources into a single analytical frame to uncover, for the first time, the global and connected histories of Eastern Christianity in the early modern world. Through the work of a team of - researchers under the close supervision of the PI, the project will reconstitute and analyse a ‘lost archive’ of literary, documentary, and printed sources in three continents, ten languages, and dozens of archives. Under the expert leadership of the - PI, the project will include a robust strategy for dissemination, which will successfully bridge the fields of Middle Eastern, European, and global history. In doing so, this project will respond directly to one of the most pressing conceptual - challenges facing global history today, that is, how to link the study of the micro-scale level of everyday life to the macro-narratives emphasised by global historians. Underlying this project, therefore, is a major intervention that seeks to - advance a rigorous form of global history, and one which preserves philology and source criticism at the heart of its methodology. The outcomes of the project will include print-publications, workshops, and a searchable database of all writings by - Eastern Christians from 1500 to 1750. - - 2020-06-30, ongoing project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - SoSGlobal - - - ERC-2014-STG - - - 638578 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - KING'S COLLEGE LONDON - - - EUR 1 794 562 - - - Higgs bundles: Supersymmetric Gauge Theories and Geometry - - - EUR 1 794 562 - - - United Kingdom - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - String theory provides a unified description of particle physics and gravity, within a consistent theory of quantum gravity. The goal of this research is to develop both the phenomenological implications as well as conceptual - foundations of string theory and its non-perturbative completions, M- and F-theory. Both, seemingly independent, questions are deeply connected to a mathematical structure, the Higgs bundle, which characterizes supersymmetric vacua of dimensionally - reduced gauge theories, and insights into the moduli space of Higgs bundles will result in a fruitful cross-connection between these subjects. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - HIGGSBNDL - - - ERC-2015-CoG - - - 682608 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE UNIVERSITY OF HERTFORDSHIRE HIGHER EDUCATION CORPORATION - - - EUR 2 499 980 - - - Divergent modes of ritual, social cohesion, prosociality, and conflict. - - - EUR 2 499 980 - - - United Kingdom - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The project aims to establish an authoritative scientific framework for understanding the relationship between group ritual, social cohesion, and pro-group behaviour. Rituals have shaped human societies for millennia, but the - exact social consequences of rituals are poorly understood. The proposed research will identify the fundamental components of rituals worldwide and chart their effects on patterns of group alignment and action. Doing so will have a lasting impact on - basic understandings of the nature, causes, and consequences of ritual dynamics as well as open up exciting new avenues of inquiry that bridge the humanities and social sciences. - - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - RitualModes - - - ERC-2015-AdG - - - 694986 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 2 066 976 - - - Uncertainty and Precaution: Environmental Decisions Involving Catastrophic Threats - - - EUR 2 066 976 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The goal of this project is to supplement or replace the precautionary principle with decision guidance that better handles both normative and empirical uncertainty in contexts of speculative but potentially catastrophic - consequences. It has been claimed that emerging technologies such as geoengineering, biotechnology, or machine intelligence could have catastrophic impacts on human civilization or the biosphere, indicating the need for precaution until scientific - uncertainty has been resolved. Yet it is unclear how to apply the precautionary principle to cases where the deeper investigations of scientific uncertainties that it calls for can themselves be a source of catastrophic risk (in e.g. gain-of-function - research and geoengineering experiments). Furthermore, the precautionary principle fails to account for moral uncertainty —even though many decisions depend more sensitively on ethical parameters (e.g. our obligations to future generations, discount - rates, intrinsic value of nature) than on remaining scientific uncertainties. - - 2020-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - UnPrEDICT - - - ERC-2014-ADG - - - 669751 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 1 980 966 - - - Foundations of Factorized Data Management Systems - - - EUR 1 980 966 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The objective of this project is to investigate scalability questions arising with a new wave of smart relational data management systems that integrate analytics and query processing. These questions will be addressed by a - fundamental shift from centralized processing on tabular data representation, as supported by traditional systems and analytics software packages, to distributed and approximate processing on factorized data representation. - - 2021-05-31, ongoing project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - FADAMS - - - ERC-2015-CoG - - - 682588 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 2 000 000 - - - A Probe of the Periodic Elements for Life in the Sea - - - EUR 2 000 000 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - "Chemical elements are the building blocks of life. The major elements, C, H. O, N, P, S are easily recognised as essential nutrients, but their use by life relies on metalloproteins. The identity of the metal centres of these - metalloproteins and even the broader palette of trace elements fundamental to life are remarkably poorly known. Whole genomes remain opaque to decoding of this bioinorganic dimension, and optimal trace element concentrations for physiological - function. Defining the elemental requirements for maximum growth rate of photosynthesising phytoplankton in the ocean, is critical to understanding Earth's climate. Although microscopic in stature, phytoplankton exert a gigantic influence on the - biological pumping of carbon from the atmosphere to the deep ocean. Yet their metal requirements are poorly constrained, being inferred from cellular quotas and "nutrient-like" ocean metal distributions, susceptible to ambiguity between mistaken - cellular uptake and use. - - - 2021-05-31, ongoing project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - APPELS - - - ERC-2015-CoG - - - 681746 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 1 599 661 - - - Comparing the Copperbelt: Political Culture and Knowledge Production in Central Africa - - - EUR 1 599 661 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project provides the first comparative historical analysis – local, national and transnational - of the Central African copperbelt. This globally strategic mineral region is central to the history of two nation-states - (Zambia and Democratic Republic of Congo (DRC)), as well as wider debates about the role of mineral wealth in development. The project has three interrelated and comparative objectives. First, it will examine the copperbelt as a single region divided - by a (post-)colonial border, across which flowed minerals, peoples, and ideas about the relationship between them. Political economy created the circumstances in which distinct political cultures of mining communities developed, but this also - involved a process of imagination, drawing on ‘modern’ notions such as national development, but also morally framed ideas about the societies and land from which minerals are extracted. The project will explain the relationship between minerals and - African polities, economies, societies and ideas. Second, it will analyse how ‘top-down’ knowledge production processes of Anglo-American and Belgian academies shaped understanding of these societies. Explaining how social scientists imagined and - constructed copperbelt society will enable a new understanding of the relationship between mining societies and academic knowledge production. Third, it will explore the interaction between these intellectual constructions and the copperbelt’s - political culture, exploring the interchange between academic and popular perceptions. This project will investigate the hypothesis that the resultant understanding of this region is the result of a long unequal interaction of definition and - determination between western observers and African participants that has only a partial relationship to the reality of mineral extraction, filtered as it has been through successive sedimentations of imagining and representation laid down over - nearly a century of urban life in central Africa. - - 2020-06-30, ongoing project - - - 2016-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - ComparingCopperbelt - - - ERC-2015-CoG - - - 681657 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 2 212 114 - - - Immunological synapse derived ectosomes in T cell effector function - - - EUR 2 212 114 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The immunological synapse is a highly conserved scaffold for communication between immune cells built around cooperation of antigen and adhesion receptors. It often takes the form of a bull’s eye with a central cluster of - antigen receptors surrounded by a ring of adhesion molecules. We have recently observed that antigen receptor coated extracellular microvesicles bud directly from the center of the immunological synapse- which we define as synaptic ectosomes. - Synaptic ectosomes are transferred to the antigen- presenting cell and can generate signals after the T cell-APC synapse has dissolved. We aim to determine the composition of synaptic ectosomes, determine their fate in the antigen-presenting cell and - identify approaches to manipulate their formation in vivo. The objectives will be to 1) isolate synaptic ectosomes from human T cells and determine their molecular composition; 2) determine the functional impact of synaptic ectosomes on the antigen - presenting cell; and 3) use gene targeting to control the process in vivo to understand its role in T function of helper, cytotoxic and regulatory T cells. The technologies will include microscopy, proteomics, genomics, and in vivo models with - constitutive and conditional gene targeting. This work will address fundamental gaps in our understanding of immune cell communication. - - 2020-10-31, ongoing project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - SYNECT - - - ERC-2014-ADG - - - 670930 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 2 447 052 - - - FLow of Ancient Metals across Eurasia (FLAME): New frameworks for interpreting human interaction in Later Prehistory - - - EUR 2 447 052 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - FLow of Ancient Metals across Eurasia (FLAME) is a new empirical and conceptual framework for understanding human interactions in Later Prehistory across all of Eurasia. Taking existing data on the chemical and isotopic - composition of copper alloy objects and combining them with typological and chronological information within a GIS framework, FLAME aims to rewrite the history of human engagement with copper and its alloys across Eurasia, from Atlantic Iberia to the - shores of the Pacific during approximately the 3rd to early 1st millennia BCE. It replaces the outdated concept of provenance with a completely new interpretative paradigm (‘form and flow’), which is built upon the expectation that copper may be - recycled, re-alloyed and generally re-used, thus breaking the simple linear assumption of a direct chemical or isotopic link between the copper and the ore from which it came. In this new paradigm, small shifts in chemistry are interpreted not - necessarily as changing ore sources but also as the natural consequence of high-temperature processing and mixing, thus putting the emphasis on human interaction with metal rather than on sourcing. We will address major questions at a range of - scales, from assemblage to continental, to look at how metal flowed literally and metaphorically through the complex societies of Bronze Age Eurasia. Our reassessment of the metallurgy will also be underpinned by new GIS frameworks and the creation - of regional Bayesian-modelled radiocarbon chronologies. Previous scientific assessments of early metal have too often isolated the chemical and isotopic evidence from both the immediate archaeological context and any sense of a real time and place. - FLAME brings together a broad range of skills to examine for the first time the intertwined social, scientific, chronological and geographical aspects of Eurasian early metallurgy. - - 2020-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - FLAME - - - ERC-2014-ADG - - - 670010 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 183 454,80 - - - The molecular basis of learning and memory: uncovering the link between neuronal activation and localized translation at the synapse. - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - During learning specific neuronal connections are strengthened and weakened to create long-term memory. This requires local regulation of the availability of proteins at the synapse, at a large distance from the cell body, in - response to neuronal activity. It is generally recognized that such synaptic plasticity can be achieved through the regulation of translation of localized mRNAs at or near the synapses. Despite the importance of this mechanism in memory and our - understanding of neurodegenerative diseases, the molecular basis by which neuronal activation regulates localised translation is still largely unknown in any system. - - - 2017-08-31, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - Syncrip_2014 - - - H2020-MSCA-IF-2014 - - - 655854 - - - - - UNIVERSIDADE DE AVEIRO - - - EUR 207 759,80 - - - Thermometry and Photoacoustic-Imaging Outstanding Nanoprobes - - - EUR 207 759,80 - - - Portugal - - - Higher or Secondary Education Establishments - - This project addresses the quest of new materials and approaches that nanotechnology requires to solve the current limitations of medicine. The potential to externally track and image organs and the potential presence and - evolution of diseases by using light becomes a reality thanks to the use of especially tailored biocompatible nanoplatforms. New avenues to image living bodies by light allied with mechanical waves (i.e. sound) are going to be opened. We propose here - an elegant marriage between light and sound endowing smartly designed nanoprobes with the capability of deep-tissue photoacoustic imaging, also accompanied by all-optical temperature sub-tissue measuring. To increase the penetration depth and spatial - resolution, an imaging approach pumping the probes with near-infrared light is proposed. Therefore, we propose a kind of material no previously exploited for photoacoustic exogenous agent, working as bimodal nanoprobe by also optically measuring - temperature within the biological transparency windows in the near-infrared - - 2019-11-30, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Portugal - - - TEMPTATION - - - H2020-MSCA-IF-2015 - - - 709270 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 2 443 640 - - - A Consolidated Library of Anglo-Saxon Poetry - - - EUR 2 443 640 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - As elsewhere in Europe, Anglo-Saxon England saw a development from an oral, vernacular, native, and pagan culture to one that was primarily literate, Latinate, imported, and Christian; and such a transition is clearest in - Anglo-Saxon verse. CLASP will focus on all surviving verse of Anglo-Saxon England, composed in Old English and Anglo-Latin over a period of over four centuries (c. 670–1100 CE), and produce for the first time an online and interactive consolidated - library, marked up through TEI P5 XML to facilitate the identification of idiosyncratic features of sound, metre, spellings, diction, syntax, formulas, themes, and genres across the entire corpus, so forging connections and suggesting more certain - chains of influence both within and between the two main literary languages of Anglo-Saxon England. The bilingual corpus comprises almost 60,000 lines of poetry, with about half surviving in each language, and mostly appearing in only a single - witness, usually in manuscript. More than fifty named poets are identified, many of them dateable with more or less precision, whose influence on each other can be closely documented, while in the case of anonymous verse, most of which is in Old - English, the focus will be on tracing potential influence between texts, to establish a comparative rather than an absolute chronology. CLASP will use the full panoply of digital resources, including sound- and image-files where relevant, to make the - oldest surviving poetry in England available to a modern audience for unprecedented kinds of exploration, comprehensive analysis, and interrogation, and in a series of conferences, workshops, and other publications will show the potential of such a - comprehensive multilingual corpus to revolutionize perspectives not only on Anglo-Saxon England, but elsewhere in Europe, where Latin and the vernacular likewise co-existed in a Christian context across centuries. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - CLASP - - - ERC-2015-AdG - - - 695262 - - - - - TECHNISCHE UNIVERSITEIT DELFT - TECHNISCHE UNIVERSITEIT DELFT - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 2 479 810 - - - Global Terrorism and Collective Moral Responsibility: Redesigning Military, Police and Intelligence Institutions in Liberal Democracies - - - EUR 2 479 810 - - - Netherlands - Netherlands - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - International terrorism, e.g. Al Qaeda, IS, is a major global security threat. Counter-terrorism is a morally complex enterprise involving police, military, intelligence agencies and non-security agencies. Counter-terrorism - should be framed as a collective moral responsibility of governments, security institutions and citizens. (1) How is international terrorism to be defined? (2) What is the required theoretical notion of collective moral responsibility? (3) What - counter-terrorist strategies and tactics are effective, morally permissible and consistent with liberal democracy? Tactics: targeted killing, drone warfare, preventative detention, and bulk metadata collection (e.g. by NSA); (4) How is this inchoate - collective moral responsibility to be institutionally embedded in security agencies? (i) How are security institutions to be redesigned to enable them to realise and coordinate their counter-terrorism strategies without over-reaching their various - core institutional purposes which have hitherto been disparate, (e.g. law enforcement versus military combat), and without compromising human rights, (e.g. right to life of innocent civilians, right to freedom, right to privacy), including by means - of morally unacceptable counter-terrorism tactics? (ii) How are these tactics to be integrated with a broad-based counter-terrorism strategy which has such measures as anti-radicalisation and state-to-state engagement to address key sources of - terrorism, such as the dissemination of extremist religious ideology (e.g. militant Wahhabi ideology emanating from Saudi Arabia) and the legitimate grievances of some terrorist groups (e.g. Palestinian state)? What ought a morally permissible and - efficacious (i) structure of counter-terrorist institutional arrangements, and (ii) set of counter-terrorist tactics, for a contemporary liberal democracy collaborating with other liberal democracies facing the common problem of international - terrorism consist of? - - 2020-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Netherlands - - - GTCMR - - - ERC-2014-ADG - - - 670172 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - AARHUS UNIVERSITET - - - EUR 2 499 913 - - - Dis-inhibitory circuits in the human cerebral cortex - - - EUR 2 499 913 - - - United Kingdom - United Kingdom - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Temporal co-ordination of the activity of cortical neurons underlies cognitive processes. Intracortical inhibitory circuits set temporal windows for modulation of glutamatergic pyramidal cell firing. In non-human mammals, the - activity of the GABAergic neurons is governed by other specialised GABAergic neurons, which can dis-inhibit pyramidal cells. The overarching aim of this project is to define cellular and pharmacological mechanisms of dis-inhibitory circuits in the - human cerebral cortex. These circuits could act as regulators of cognitive process. First, we will investigate the neuron types and their synaptic influences to characterise how dis-inhibition controls synaptic integration and the output of neurons. - Second, we will elucidate synaptic plasticity in dis-inhibitory circuits, as plastic events likely represent physiological substrates of cognitive operations. Third, we will identify the subcellular sites and the mechanisms of action of key receptors - for ACh, monoamines, endocannabinoids, neuropeptides and mGluRs modulating dis-inhibitory circuits, which are targets of small molecule CNS drugs, such as cognitive enhancers. We will test three hypotheses: 1) the human cortical pyramidal cell output - is gated by compartment-specific dis-inhibition mediated by specific interneurons; 2) activity-dependent plasticity occurs in dis-inhibitory circuits and has consequences for the output of cortical pyramidal neurons; 3) small molecule drugs act via - dis-inhibitory mechanisms at cell-type specific sites altering the inhibitory dynamics of pyramidal cells leading to subcellular redistribution of inhibition and alteration in their output. Combined electrophysiology/imaging with neuropharmacology - and high resolution molecular receptor localisation will generate an unprecedented knowledge of the human cortical circuits. Understanding human cortical neuronal connections and their responses to pharmacological interventions may also lead to novel - therapeutic strategies. - - 2021-11-30, ongoing project - - - 2016-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - INHIBITHUMAN - - - ERC-2015-AdG - - - 694988 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 2 462 015 - - - Perception Ultrasound by Learning Sonographic Experience - - - EUR 2 462 015 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - PULSE will develop a new generation of ultrasound imaging capabilities to revolutionize the use of this low-cost and portable imaging technology across clinical medicine worldwide. - - - 2021-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - PULSE - - - ERC-2015-AdG - - - 694581 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - HELSINGIN YLIOPISTO - - - EUR 1 998 375 - - - Bio-Imaging of Zoonotic and Emerging Bunyaviruses - - - EUR 1 998 375 - - - United Kingdom - United Kingdom - Finland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - We aim to understand host cell entry of enveloped viruses at molecular level. A crucial step in this process is when the viral membrane fuses with the cell membrane. Similarly to cell–cell fusion, this step is mediated by - fusion proteins (classes I–III). Several medically important viruses, notably dengue and many bunyaviruses, harbour a class II fusion protein. Class II fusion protein structures have been solved in pre- and post-fusion conformation and in some cases - different factors promoting fusion have been determined. However, questions about the most important steps of this key process remain unanswered. I will focus on the entry mechanism of bunyaviruses by using cutting-edge, high spatial and temporal - resolution bio-imaging techniques. These viruses have been chosen as a model system to maximise the significance of the project: they form an emerging viral threat to humans and animals, no approved vaccines or antivirals exist for human use and they - are less studied than other class II fusion protein systems. Cryo-electron microscopy and tomography will be used to solve high-resolution structures (up to ~3 Å) of viruses, in addition to virus–receptor and virus–membrane complexes. Advanced - fluorescence microscopy techniques will be used to probe the dynamics of virus entry and fusion in vivo and in vitro. Deciphering key steps in virus entry is expected to contribute to rational vaccine and drug design. During this project I aim to - establish a world-class laboratory in structural and cellular biology of emerging viruses. The project greatly benefits from our unique biosafety level 3 laboratory offering advanced bio-imaging techniques. Furthermore it will also pave way for - similar projects on other infectious viruses. Finally the novel computational image processing methods developed in this project will be broadly applicable for the analysis of flexible biological structures, which often pose the most challenging yet - interesting questions in structural biology. - - 2020-03-31, ongoing project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - BIZEB - - - ERC-2014-CoG - - - 649053 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 2 481 744 - - - Elucidating natural bilayer lipid environments - - - EUR 2 481 744 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Excising a membrane protein from its natural environment, preserving the lipid bilayer, and characterising the lipids that surround it is the ‘holy grail’ of membrane protein biophysics. However, with some 40,000 different - lipid structures the challenges we face in understanding selective binding arise not just from the complexity and dynamics of the lipidome, but also from the transient nature of protein lipid interactions. To overcome these challenges we will take - mass spectrometry (MS) into a new era, allowing, for the first time, the study of proteins in an environment as close as possible to the natural one. To do this we will (i) characterise protein lipid interactions by employing a high resolution - Orbitrap mass spectrometer developed in-house, specifically for membrane proteins, (ii) capture the native lipid environment in vehicles suitable for use in conjunction with MS, and (iii) establish a new platform to be known as integral membrane - protein desorption electrospray ionization (impDESI). Designed and built in-house impDESI is capable of releasing membrane proteins from surfaces directly into the mass spectrometer (MS). We will develop impDESI for membrane mimetics, and - subsequently portions of natural membranes, enabling us to extract proteins with oligomeric state preserved and native lipid binding intact. The development of impDESI, in conjunction with high resolution Orbitrap MS, and coupled with the - optimisation of membrane mimetics, has the potential to radically transform our understanding of native lipid binding, not only directly, but also temporally and spatially. Together these advances will answer key questions about how lipids modulate - protein interfaces, occupy different binding sites, modulate membrane protein structure and modify function in vivo. Given the importance of membrane proteins as potential drugs targets understanding their modulation by lipids would be a major step - towards more effective drug development. - - 2021-05-31, ongoing project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - United Kingdom - - - ENABLE - - - ERC-2015-AdG - - - 695511 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 1 395 933 - - - Algorithms for Complex Collective Decisions on Structured Domains - - - EUR 1 395 933 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Algorithms for Complex Collective Decisions on Structured Domains. - - - 2020-06-30, ongoing project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - ACCORD - - - ERC-2014-STG - - - 639945 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 1 480 632 - - - Coevolutionary Policy Search - - - EUR 1 480 632 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - I propose to develop a new class of decision-theoretic planning methods that overcome fundamental obstacles to the efficient optimization of autonomous agents. Creating agents that are effective in diverse settings is a key - goal of artificial intelligence with enormous potential implications: robotic agents would be invaluable in homes, factories, and high-risk settings; software agents could revolutionize e-commerce, information retrieval, and traffic control. - - 2020-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - CoPS - - - ERC-2014-STG - - - 637713 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 195 454,80 - - - The logics of information visualisation - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Information visualisation is an essential tool in data-science, but the lack of a theoretical foundation currently prevents visualisation science to make substantial progress and develop solutions for the epistemological challenges posed by Big Data. - - 2017-09-30, closed project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - LOGIVIS - - - H2020-MSCA-IF-2014 - - - 657017 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 1 497 271 - - - Integrated and Detailed Image Understanding - - - EUR 1 497 271 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The aim of this project is to create the technology needed to understand the content of images in a detailed, human-like manner, significantly superseding the current limitations of automatic image understanding, and enabling - new far reaching human-centric applications. The first goal is to substantially broaden the spectrum of visual information that machines can extract from images. For example, where current technology may discover that there is a "person" in an image, - we would like to produce a description such as "person wearing a red uniform, tall, brown haired, with a bayonet, and a long black hat." The second goal is to do so efficiently, by developing integrated image representations that can share knowledge - and computation in multiple computer vision tasks, from detecting edges to recognising and describing thousands of different object types. - - 2020-07-31, ongoing project - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - IDIU - - - ERC-2014-STG - - - 638009 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 148 377 - - - ExtraLytics: Big Data Analytics for Real Estate - - - EUR 148 377 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Data is becoming the key to effective decision making in more and more aspects of modern society. Big data analytics provide insight into complex processes considering a breadth of factors. This promises to increase the - efficiency of decision making in areas such as policy making, research, product development, or financial and retail markets. Currently, big data analytics is employed only by technologically savvy organisations with control over the relevant data. - This further exacerbates the information asymmetry that has been plaguing many of these areas: real estate where buyers have long suffered from limited information, often controlled by the seller; or retail markets where sellers are now employing - sophisticated competitive price intelligence solutions unaffordable to buyers. Who can tell you if it is better to buy a house with a garden or with a garage; or where renovations will yield more rent over time? ExtraLytics answers these questions - through a combination of big data extraction and analytics. ExtraLytics introduces analytics and prediction models into DIADEM’s platform for accurate big data extraction from the web, which is able to extract required data at massive scale from the - web. For the proof-of-concept, ExtraLytics initially focuses on residential real estate in the UK, a £4,135bn market (UBS), where buyers and renters are required to make fast decision with limited information—time on market is often below a week or - even below a day as for desirable rentals in Oxford. “In an age when ‘big data’ is shaping our every move, how come an industry that takes so much profit can’t keep pace with technology and use it to actually deliver a service worth the money they - take in commission?” (The Telegraph). ExtraLytics addresses this lack of data-driven analytics by giving consumers and investors alike a tool for better understanding properties, their location, their neighborhood, and their investment potential - compared to other properties. - - 2016-04-30, closed project - - - 2014-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2014 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - ExtraLytics - - - ERC-2014-PoC - - - 641222 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 1 954 633 - - - Social Evolution and Social Engineering of bacterial Infections - - - EUR 1 954 633 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Micro-organisms were believed until recently to live independent, unicellular lives but are now understood to rely on complex systems of social behaviours for survival. In pathogenic bacteria, cooperation and communication - between cells leads to increased virulence and the understanding of how these behaviours evolve is of fundamental importance to the future of human health. Almost nothing is known, however, about social behaviours of bacteria infecting human hosts, - and research on social behaviour in microbes is limited to well-characterised lab strains. This proposal describes a program of research designed to exploit the opportunities offered by an interdisciplinary approach to address the growing challenge - posed to human health by disease caused by bacterial infection. Specifically, I have three primary objectives: (1) to develop a model system for investigating social behaviour in long-term bacterial infections; (2) to identify evolutionary mechanisms - driving dynamics of social behaviour in long-term infections and (3) to exploit social dynamics in the treatment of bacterial infection. This proposal applies evolutionary theory to the clinical challenge of bacterial infection to develop novel - intervention strategies beyond the scope of conventional medicine, which is based primarily on understanding of bacteria at the cellular level. - - 2020-07-31, ongoing project - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - SESE - - - ERC-2014-CoG - - - 647586 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 195 454,80 - - - Role, regulation and targeting of nucleic acid-sensing TLRs within the tumour microenvironment - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Inflammation is an integral part of carcinogenesis. Several different cells of myeloid, lymphoid and non-hematopoietic origin contribute to the strong link between cancer and inflammation and maintain a pro-tumoral - environment. The complexity of this environment and the diversity of tumours lead to distinct responses during tumour immunotherapies. Nucleic acid-sensing (NAS) TLR ligands are an essential component of anti-tumour strategies to induce efficient - tumour-specific adaptive immune responses. NAS TLRs can also detect nucleic acid released during tumour necrosis, thereby modulating the tumour microenvironment. Interestingly, NAS TLR signalling can induce cell death via apoptosis or induce - pro-tumoral survival and proliferation of cancer cells. These opposing effects of NAS TLR ligands may be due to the differential response of distinct tumour-associated cells to TLR ligands. Indeed, the individual response of subsets of - tumour-associated cells remains unclear, thus making it difficult to predict the outcome of tumour immunotherapies. Furthermore, the expression and regulation of NAS TLRs in tumour-associated cells remains unknown. Using ex vivo cultures from - adenocarcinomas and melanomas, we will systematically analyze the expression of all NAS TLRs on sorted cells. Using cutting edge technologies, we will dissect the role of TLRs in modulating the tumour microenvironment, which will provide novel - insights into our ability to modulate cellular inflammation in the tumour. This proposal has the potential not only to reveal novel aspects of NAS TLR regulation, but also to provide new targets for the modulation of the tumour stroma and the - infiltrating cells during carcinogenesis. - - 2017-09-30, closed project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - Tolltum - - - H2020-MSCA-IF-2014 - - - 656757 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 183 454,80 - - - Network Techniques for Interaction Quenches - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Understanding the universal features of the non-equilibrium dynamics of strongly interacting one-dimensional quantum many-body systems is one of the most challenging and intriguing aspect of the recent researches in the broad - domain of the quantum many-particle physics. In this project one merges analytical with numerical methods in order to explore the exotic behavior of interacting quantum models when brought out-of-equilibrium. Indeed, although the equilibrium - properties of quantum systems could be understood in terms of standard approaches, away from the equilibrium a complete understanding is still missing. In particular, the project aims to fill the lack of knowledge still present in this exciting - domain, pursuing two main ideas: (i) The development of new numerical methods based on tensor-network techniques, so as to explore the post-quench dynamics in closed quantum systems; with a special attention to the very recent continuous version of - such algorithms. (ii) A better theoretical understanding (strongly supported by the numerical approach in (i)) of the effects of symmetry breaking, interactions and integrability, in the non-equilibrium dynamics; especially with respect to the - non-equilibrium transport of energy and particle throughout the systems as well as a universal description of the stationary states (both equilibrium and non-equilibrium) that emerge at late times. - - - 2018-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - NET4IQ - - - H2020-MSCA-IF-2015 - - - 701221 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 183 454,80 - - - Boundaries of Science: Medieval Condemnations of Philosophy as Heresy - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - ‘Boundaries of Science: Medieval Condemnations of Philosophy as Heresy’ addresses the limits we place on scientific investigation, according to our world view and what new ideas we are prepared to accept. It focuses on a - critical example during the foundation of modern science in the 13th/14th centuries, when Aristotelian natural philosophy (books by Aristotle and his Muslim interpreters) entered Europe. This alien thinking caused a scientific revolution, but sparked - controversy where theories denied Christian doctrines central to society’s outlook. Church and university authorities opposing dangerous theories condemned them, and investigated scholars. This project builds on my surprising discovery that some - medieval scholastics labelled theories heretical, but in fact the theories did not fit heresy’s medieval definition. Curiously, some who used the term held risky positions. My objective is to determine whether scholastics considered dangerous - theories heretical. Preliminary findings indicate some thought they should be classed as such; while others used the term for protection when holding risky views. Both groups acted strategically, to condemn or promote theories. I believe we witness - here a negotiation process of where the boundary to permitted science should be drawn. My approach is new: historiography on the subject relies on scarce documentary evidence; instead I examine a rich source novel for this question, cases of - scholastics calling theories heretical in philosophical/theological writings, and I analyse the context to determine their motivation. In redefining the philosophy/heresy relationship, I will give robust new perspective to the reception history and - faith/reason problem. This innovative, multidisciplinary project will make a fact-based contribution to discussion of boundaries we place on scientific thinking, and will impact on how scholars and European society perceive the origins and - development of our scientific heritage. - - 2018-09-14, ongoing project - - - 2016-09-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - BoundSci - - - H2020-MSCA-IF-2015 - - - 701523 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 145 501 - - - Integral Membrane Proteins – an Approach to Rank Target Stability - - - EUR 145 501,25 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This Proof of Concept proposal is designed to develop and test a novel way of monitoring the effects of drug binding to membrane protein targets. The idea stems from the basic research proposed in my ERC grant IMPRESS to study - and rationalise the release of membrane proteins from detergent micelles in the gas phase of the mass spectrometer. During this research we discovered a new family of detergents, which we could formulate, to retain folded protein structure in the gas - phase. Having achieved this goal, we then actively unfolded these assemblies in the mass spectrometer and by monitoring their unfolding trajectories we realised that we could quantify the effects of small molecule binding on protein stability. Not - only can we now rank ligands according to their ability to confer stability but we can also count the number of molecules bound to a particular membrane protein target. By distinguishing bound molecules, either lipids or drugs, we can then carry out - competitive binding experiments by displacing small molecules with higher affinity ligands. - - 2016-08-31, closed project - - - 2015-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2014 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - IMPARTS - - - ERC-2014-PoC - - - 641317 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 195 454,80 - - - Approaching efficiency limits of perovskite solar cells by overcoming non-radiative recombination losses - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Metal halide perovskites are currently viewed as a new “wonder materials” due to the combination of their outstanding optical and electronic properties with the ease of processing as compared to similar direct bandgap - semiconductor such as GaAs. Despite the meteoric rise of the power conversion efficiency of perovskite solar cells (up to 20% in less than 5 years) they is still a substantial potential of improvement towards the theoretical efficiency limits. During - the first research phase, most of the effort has been devoted to the development of deposition processes to produce the best crystalline thin films. APPEL has the ambition to initiate the second phase, in which fundamental understanding of the - recombination losses in the perovskite and at heterojunctions with charge extraction layers will make possible to generate devices with efficiencies approaching the full potential of these semiconductors. A perfect solar cell should also be an - excellent emitter, since 100% of the absorbed photons must recombine radiatively. Therefore the original approach APPEL is to target primarily light emission (photoluminescence and electroluminescence) to understand the factors governing the - recombination losses in solar cells. From the understanding of the fundamental recombination mechanisms at the heterojunctions, I will demonstrate highly efficient devices with >23% power conversion efficiency. Moreover, efficient light-emitting - diodes (LED) will be produce alongside photovoltaic devices. This work will set the foundation of the future rational optimisation of metal halide perovskite devices in the same way that optimisation of light emission in GaAs led to the advent of - devices approaching the theoretical limits. - - 2018-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - APPEL - - - H2020-MSCA-IF-2015 - - - 706552 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 195 454,80 - - - Imaging nucleic acid metabolism in cells - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - In this project I, Pawan Kumar, a Nucleic Acid Chemist seek to team up with a pioneer in Nucleic Acid Chemistry and Biology (Professor Tom Brown) to carry out a highly interdisciplinary study at the University of Oxford to - obtain deeper insights into DNA and RNA synthesis and metabolism in living cells and its application to cancer research. I propose to detect and quantify nucleic acid synthesis in proliferating cells by fluorescence without the requirement for toxic - metal ions or antibodies. Earlier known methods such as [3H]thymidine and 5-bromo-2'-deoxyuridine labelling are either slow and labour intensive or require the use of harsh conditions. Incorporation of 5-ethynyl-2'-deoxyuridine into newly synthesized - DNA and its subsequent detection with an azide derivative of a fluorescent dye under copper catalyzed alkyne azide cycloaddition (CuAAC) reaction conditions presents a better alternative. However, cytotoxicity of copper salts restricts its use for - living cells. I will use the strain promoted alkyne azide cycloaddition reaction, Diels-Alder reaction, and inverse electron demand Diels-Alder reaction to study cellular DNA and RNA. None of these reactions require the use of toxic metal salts. I - will develop the conditions under which both DNA and RNA will be stable, so that it will be possible to isolate intact fluorescent nucleic acids from cells for detailed analysis. I will prepare the modified nucleosides and use them to label newly - synthesized DNA and RNA in cells enabling their detection by reaction with fluorophores by using metal free click ligation reactions. The study will provide a better understanding of the mechanisms regulating DNA replication and the interplay between - transcription and DNA replication. In the project I will develop techniques to provide information on the toxic effect of antimetabolites used commonly in anti-cancer therapies, and for identifying the mechanisms of viral replication and - understanding the viral life cycle. - - 2018-01-03, closed project - - - 2016-01-04 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - INAME - - - H2020-MSCA-IF-2014 - - - 656872 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 150 000 - - - A portable single-molecule fluorescence imager - - - EUR 150 000 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This proposal focuses on activities that support the advancement of a novel compact optical microscope to the proof-of-concept stage. The microscope (“NanoImager”) is based on single-molecule fluorescence imaging; its - development resulted from efforts to improve microscopes within the ERC project POLMACHINE. - - - 2016-05-31, closed project - - - 2014-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2014 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - NANOIMAGER - - - ERC-2014-PoC - - - 641252 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 183 454,80 - - - Combined Catalysis: Enhancing Asymmetric Synthesis - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The stereoselective synthesis of small organic molecules depends on robust catalytic methods. Despite many advances in enantioselective synthesis, an unsolved challenge in catalysis is the translation of enantioselective - catalytic reactions to diastereoselective reactions – where a chiral catalyst controls the outcome of reaction of a chiral substrate. - - - 2018-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - CombiCat - - - H2020-MSCA-IF-2015 - - - 702385 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 183 454,80 - - - VINYL AND HETEROARYL BORONIC ACIDS AS NON-STABILIZED NUCLEOPHILES IN RHODIUM-CATALYZED DYNAMIC KINETIC TRANSFORMATIONS - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The formation of carbon-carbon bonds in an asymmetric fashion is a very useful process in synthetic chemistry, since it generates single enantiomers of chiral molecules at the same time as the molecular framework is being - assembled. In this context, two strategies for the generation of single enantiomer compounds using enantioselective catalysis have been widely emabraced: on the one hand, the use of prochiral substrates, and on the other hand, the use of racemic - substrates in enantiomer resolution processes, which limits the yields up to 50%. An efficient variation of this second strategy is to couple enantiomer differentiation with interconversion of enantiomers. However, these dynamic kinetic asymmetric - transformations (DYKAT) have been limited to the use of stabilized nucleophiles. Very recently, the group of Fletcher reported that alkylzirconium reagents can be employed as non-stabilized nucleophiles in combination with a copper-based catalytic - system for this class of processes. Subsequently, the same group demonstrated that arylboronic acids are also suitable substrates in rhodium-catalyzed DYKATs. The project presented in this application aims to expand the scope of this powerful - transformation by using vinyl- and heteroarylboronic acids as non-stabilized nucleophiles in the rhodium-catalyzed DYKAT. Moreover, a thorough study of the reaction mechanism will be conducted, as well as the investigation on alternative procedures - for this process (catalytic systems, nature of the substrates, etc) that might result in useful applications for organic synthesis. - - 2018-07-31, ongoing project - - - 2016-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - BORONDYKAT - - - H2020-MSCA-IF-2015 - - - 700108 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 183 454,80 - - - Chemical Tools to Probe the Role of Bromodomains in the Parasite Trypanosoma cruzi - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Lysine acetylation is a key protein post-translational modification (PTM) found throughout the cellular environment and across the range of species. This PTM is dynamic, with histone acetyl transferases (HATs) acetylating - lysine, and histone deacetlyases (HDACs) reversing the modification. In addition, proteins modules bromodomains, have been identified that bind to acetylated lysine (KAc) and mediate protein-protein interactions. In humans, bromodomains exist as part - of larger proteins, many of which are involved in transcriptional regulation. Bromodomains contain a KAc-binding pocket for which small molecule ligands have been identified. These ligands prevent the interaction of bromodomains with KAc and have - been invaluable in dissecting the fundamental biology mediated by bromodomain-containing proteins (BCPs). We and others have developed potent ligands for the human bromodomain and extra C-terminal domain (BET) bromodomains. These compounds have - antiproliferative effects in cancer cells lines and modulate inflammation and atherosclerosis. This work led to an explosion of interest in developing BET bromodomain inhibitors, resulting in 5 compounds in clinical trials. Despite rapid progress in - understanding the role of human bromodomains, their function in other species is poorly understood. Given the fundamental role played by bromodomains in humans, we hypothesise that BCPs will play equally important roles in other organisms. - - 2018-03-23, ongoing project - - - 2016-03-24 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - jamclay - - - H2020-MSCA-IF-2014 - - - 658825 - - - - - TURUN YLIOPISTO - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - UNIVERSITY OF STRATHCLYDE - ALBERT-LUDWIGS-UNIVERSITAET FREIBURG - UNIVERSITA DEGLI STUDI DI MILANO - UNIVERSITAT DE LES ILLES BALEARS - University of Science and Technology of China - - - EUR 2 268 746 - - - Quantum Probes for Complex Systems - - - EUR 2 268 746,25 - - - Finland - United Kingdom - United Kingdom - Germany - Italy - Spain - China - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - We are on the verge of a new scientific and technological era as the first quantum simulators able to investigate physical systems that cannot be studied classically are about to be built in the laboratories. Controlling and - probing complex quantum systems is of paramount importance for the implementation of these devices. - - 2018-03-31, ongoing project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.2."> - - - FETPROACT-3-2014 - Quantum simulation - - - RIA - Research and Innovation action - - - Finland - - - QuProCS - - - H2020-FETPROACT-2014 - - - 641277 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 195 454,80 - - - Bacterial motion in polymer solutions and biogels - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Many cavities in the human body such as the lungs, the stomach or the reproductive tract are covered and protected by a thin layer of mucus gel. Under certain conditions pathogenic bacteria are able to penetrate the mucus - layer which leads to serious infections. For example, in cystic fibrosis motile bacteria swim through the mucus layer and form biofilms which can be resistant to antibiotic medication. Interestingly, corals in the ocean are also covered by mucus. - Again, pathogenic bacteria are able to penetrate the coral mucus layer and cause serious diseases resulting in a world-wide decline of corals. The underlying mechanisms how the bacteria are able to move through mucus are not yet understood. We aim, - in our proposal, to clarify physical conditions under which bacterial locomotion in polymer solutions and gels is possible. In contrast to existing theories on swimming in viscoelastic fluids we explicitly model the gel and the bacteria via mesoscale - computer simulations. Our novel approach will enable us to identify the microscopic conditions for bacterial locomotion in gels and the conditions for immobility (gel-trapping). Our findings may also inspire biologists and medical researchers in - designing novel medication and finding strategies to avoid bacterial invasion into mucus of relevance to both the prevention of human disease and the degradation of corals. - - 2018-02-25, ongoing project - - - 2016-02-26 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - GelSwimming - - - H2020-MSCA-IF-2014 - - - 653284 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 183 454,80 - - - Quantum Broadband Optical Solid-State Memories for Large-Scale Photonic Networks - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Large-scale quantum photonic networks promise to revolutionize computational processing and communication with the use of fundamental quantum-mechanical concepts. Limited by scalability, the field of quantum information - processing (QIP) is so far lacking a real world, large-scale implementation that can allow for quantum computation and long distance quantum communication. These applications in QIP have distinct advantages over their classical counterparts. Quantum - computation promises to provide unprecedented speed-up in processing for problems that are intractable for classical computers, while remote entanglement generation and swapping would allow long distance quantum networking. Integral to a functioning - quantum network is a quantum optical memory (QM), a device allowing for the faithful storage and recall of quantum states of light using a strong and controllable light-matter interaction. The main scientific vision of this project is to develop - multiple cavity-enhanced, broadband and long-lived QMs capable of long distance distribution of entanglement and multi-photon state generation. The resulting technology will provide the necessary resources for long-distance quantum communication and - scalable quantum computing. The former is obtained by the heralded entanglement of two remote QMs to form an ‘elementary link’, and then swapping the entanglement between multiple links. The objective of this project is to implement the QM in a - solid-state, scalable architecture. - - 2018-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - Quantum BOSS - - - H2020-MSCA-IF-2015 - - - 705278 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 183 454,80 - - - Molecular Spintronics using Isolated Rare Earth Magnets - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - A revolution is underway, as the fast-paced electronics industry moves towards the nanoscale, researchers are starting to consider single-molecule electronics. Such devices are within reach partly due to a new field, called - molecular spintronics, which permits the prospect of controlling both spin and charge in single molecules. On the other hand, we know almost nothing about how a magnetic molecule is affected by electrons flowing through it or what chemical - ingredients it takes to construct perspective devices. SpinReMag will investigate these uncharted waters by exploring the boundary between chemistry and single-molecule read-out technology. SpinReMag is a strongly multidisciplinary project utilizing - an innovative mix of synthetic chemistry, physics and materials methodology to overcome present experimental limitations. Our design approach is to investigate single-molecule junctions, except instead of placing a molecules between bulk electrodes, - we will directly grow photoactive groups on the molecule so that electrons will flow through or close to the spin center after a light pulse. This affords an ultra-clean system that can be studied in bulk, with a perfectly defined geometry of the - magnetic and electronic elements. SpinReMag will provide the fundamental ground work to explain how molecular spins interact with flowing electrons. The execution of this project will for the first time provide the understanding of fundamental - spintronic processes, and open new pathways to the rational design of single-molecule spintronics. The information gathered by SpinReMag will direct the future of research in single-molecule electronics and in the optical control of spin systems in - general. - - 2019-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SpinReMag - - - H2020-MSCA-IF-2015 - - - 707252 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 195 454,80 - - - How prior brain states govern access to working memory - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The ability to temporarily maintain and manipulate information in working memory (WM) is critical for adaptive behaviour. Because WM has limited capacity, it is essential to understand the mechanisms that govern selective - access to it. I hypothesise that 1) selective access to WM is governed by states of the brain prior to the encoding and retrieval of sensory information (in particular the phase and amplitude of neural oscillations in the different sensory cortices), - and that 2) changes in these states provide a common neural substrate through which several cognitive variables affect WM. I will use magneto-encephalography (MEG) to investigate several key aspects of these central hypotheses in healthy human - volunteers. This will advance our understanding of the neural and cognitive mechanisms that govern selective access to WM and could ultimately be used to present relevant information when the brain is most susceptible to incorporate this into WM. The - project will be carried out at the Oxford Centre for Human Brain Activity, together with leading scientist in the electrophysiological study of WM (Anna Christina Nobre and Mark Stokes) and the analysis of MEG data (Mark Woolrich). This will allow me - to not only perform the proposed research to the highest standard, but also to further develop several key skills (broaden my conceptual horizon, acquire novel analysis techniques, establish long-term collaborations, translate research, etc.) that - will further my independence as a researcher and place me in the ideal position to start my own research group within few years after the fellowship. - - 2018-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ACCESS2WM - - - H2020-MSCA-IF-2014 - - - 655374 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 183 454,80 - - - Selectively Targeting Oscillations in Parkinson's disease: Causal effects of the beta-rhythm on motor control - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Parkinson’s disease is a frequent and disabling neurological disorder, which heavily impairs patients’ ability to perform and control movements. Electrical stimulation of a deep-seated brain region, the subthalamic nucleus - (STN), has been shown to significantly improve patients’ motor function and quality of life. Recent technological advances in deep brain stimulation (DBS) render it possible to adjust electrical stimulation of the STN to ongoing brain activity, - referred to as closed-loop DBS. Here, the implanted electrodes do not only send signals to the brain but also read out neural signals generated by the brain. Closed-loop DBS offers the intriguing possibility to specifically suppress pathological - brain activity while leaving physiological activity unaltered. - - - 2017-04-30, closed project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - STOP-Beta - - - H2020-MSCA-IF-2014 - - - 655605 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 195 454,80 - - - An innovative approach for the study of culinary practices in past societies - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The aim of this project is to develop an innovative methodology for the study of culinary practices (cuisine) in past societies integrating the morpho-typological analysis of cooking pots, the analysis of their lipid content - and the analysis of microbotanical remains. By analysing a society's diet and cuisine we can explore, for instance, cultural development expressed through growing complexity in parallel with the development of more complex social and technological - structures. This project will explore culinary practices in past societies through the integrated analysis of phytoliths, starch grains and lipids from cooking pottery. In order to interpret the archaeological record, extensive plant reference - collections and several experiments will be developed as part of the project. At the same time, the methods developed during the experimentation phase will be tested and validated on two archaeological case studies in the Aegean, an area that has - historically been (and still is) a crossroad for people and foodstuffs: the Neolithic site of Stavroupoli (Greek Macedonia, ca. 5600-5000 cal. BC) and the Bronze Age site of Knossos-Gypsades (Minoan Crete, ca. 3650-1100 cal. BC). The development of - these integrated analyses on Neolithic and Bronze Age settlements will allow for the study of the emergence of new social practices and cultural identities linked to the origins of food production and the development of complex, urban societies. - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - CUISINE - - - H2020-MSCA-IF-2015 - - - 704867 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 183 454,80 - - - An evolutionary approach to automated norm synthesis for multi agent systems - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The field of multi-agent systems (MAS) is concerned with the theory, design, and implementation of systems of semi-autonomous software agents that operate in an environment, and typically have conflicting goals. A key issue in - such domains is that of coordination: how to design agents to minimise any potential negative aspects of their interactions, and to maximise any potential positive aspects. A key approach to coordination is that of normative systems. A normative - system defines constraints on the behaviour of agents to coordinate their interactions. This research programme is at the intersection of normative systems design and evolutionary game theory (EGT). EGT studies how evolutionary forces can lead - populations to game theoretic solutions, and has been useful in understanding, for example the distributions of populations of species in habitats. The hypotheses of this project are that (1) EGT can provide a useful mathematical framework to model - and understand normative systems in MAS; and (2) EGT techniques can provide a powerful framework to engineer normative systems for MAS. Thus, norm synthesis will consist of an evolutionary process in which most successful norms will prosper, while - unsuccessful norms will be naturally discarded. The tools used to understand such norms will be solution concepts from EGT - notably the concept of an evolutionarily stable strategy. In this project we will develop both frameworks for understanding - EGT for normative systems design and to synthesise normative systems for MAS, and we will empirically investigate our techniques in the context of two application domains. To carry out this project the fellow will be trained in classical game theory - and EGT. To this aim he will benefit from supervision of Prof Michael Wooldridge, and collaboration with his research group in Oxford. This project will develop science and will contribute to the development of the fellow's career plan to become an - independent researcher. - - 2018-06-05, ongoing project - - - 2016-06-06 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - EVNSMAS - - - H2020-MSCA-IF-2015 - - - 707688 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 183 454,80 - - - Total Synthesis of Biologically Important Pyrrolidinone Natural Products and Analogues Thereof. - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - "The importance of natural products and derivatives as sources of new drugs is undeniable. Newman has stated: - - 2018-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SYNOX - - - H2020-MSCA-IF-2015 - - - 708354 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 183 454,80 - - - Molecular mechanisms of rhomboid-like proteins in human immunity - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The immune system coordinates vital responses against a plethora of threats. It relies on well-described signalling networks via soluble proteins and cell-to-cell contacts. The secretory pathway traffics all secreted and - surface proteins, but the mechanism of how immune cells control this process is unclear. - - 2017-04-06, closed project | - - - 2015-04-07 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - RhomBioID - - - H2020-MSCA-IF-2014 - - - 655035 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 195 454,80 - - - Selecting, Creating and Modifying Embryos: the ethics of new reproductive genetic technologies - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - For over three decades reproductive technologies have been available which allow parents to select between embryos based on their genetic makeup. Soon two novel ways of influencing a child’s genome could also become available. - In 2013, personal genomics company 23andMe received a patent to a technology called ‘Gamete Donor Selection Based on Genetic Calculations.’ This technology would allow individuals accessing assisted reproductive services to choose between sperm or - egg donors based on the likelihood of the embryos having a particular genetic makeup. Technologies like this allow parents to create rather than select embryos with desirable genetic characteristics. In addition genetic engineering technologies - continue to improve. The recently developed ‘CRISPR’ technique provides a more precise way of altering the genome than previous methods, and is the first modification technology with real potential to be used on human embryos. Technologies like this - may allow parents to modify the genetic material of existing embryos. - - - 2017-08-31, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SCME - - - H2020-MSCA-IF-2014 - - - 659700 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 195 454,80 - - - Multi-resolution Fracture Models for High-strength Steels: Fully Ductile Fracture to Quasi-cleavage Failure in Hydrogen Environment - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Recent advances in Computational Mechanics are towards the development of predictive tools that can accelerate the 'Materials Development Cycle' by unraveling the linkage between macroscopic properties and microstructure. The - availability of 3D tomographic tools and the era of Exascale computing have initiated the quest to develop stronger, tougher and more durable alloys by employing 'virtual predictions' in lieu of expensive destructive testing. However, our lack of - understanding of the 'structure-toughness’ relations is one of the main bottlenecks in this pursuit. Moreover, the uptake of some of these new alloys (TRIP, TWIP etc) is hampered by the concerns of hydrogen (H) induced cracking. - - - 2018-11-30, ongoing project - - - 2016-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - FraMoS - - - H2020-MSCA-IF-2015 - - - 701897 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 195 454,80 - - - Development of fluorescence nanospectroscopy to elucidate the roles of nanoscale molecular segregation in the activation of T-cells - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - BACKGROUND - - 2018-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - FNS-4-NAMOSAT - - - H2020-MSCA-IF-2015 - - - 707348 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 195 454,80 - - - From individual cognition to collective intelligence - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - In many taxa, individuals form groups that collectively process information and make decisions. Through pooling information, these groups can theoretically achieve better decisions than solitary agents. However, it has become - increasingly clear that understanding successes and failures of collective decision-making requires a detailed understanding of individual cognitive abilities and of information transfer among group members. I would like to build on my background in - social insect collective behavior to investigate a longstanding question in complex systems science: when and how does collective intelligence emerge from individual cognition? I propose to elucidate this issue using novel experiments with homing - pigeons–a species that has numerous advantages as a model system. First, pigeons can process information both individually and collectively. When flying alone, each pigeon establishes idiosyncratic habitual routes over time, based on memorized chains - of landscape cues. Flocks of pigeons are also collectively able to develop distinctive routes. Thus, I can directly compare the cognitive performance of individuals and groups by giving them the same spatio-cognitive tasks. Second, as pigeons have - been among the most important subjects in laboratory experiments on animal cognition, a wealth of data is available on pigeons’ individual cognition. Finally, cutting-edge GPS devices provide high-resolution spatiotemporal data, allowing me to create - and validate highly detailed individual-based models. My results will be applicable to multiple research fields, including optimal decision-making theory and collective robotics. - - 2018-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - GROUPCOG - - - H2020-MSCA-IF-2014 - - - 654724 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 183 454,80 - - - Site-selective chemical pyrophosphorylation of proteins using tag-and-modify approach. - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Post-translational modifications (PTMs) occur on nearly all proteins in eukaryotic cells to diversify their proteome. These chemical modifications of various amino acids side chains can influence protein association with other - biomolecules, or control cellular signal transduction networks and the activity of enzymes. Reversible protein phosphorylation is one of the most common PTMs. It is considered as a signalling mechanism involved in almost all cellular processes. On - the other hand, protein pyrophosphorylation mediated by the inositol pyrophosphate messengers was discovered recently and its function on proteins is completely unknown. Up to date, direct evidence of its role in vivo is still missing. Exploring the - potential role of protein pyrophosphorylation is limited by lack of a robust method of installing pyrophosphate residue in desired position of full length proteins. Here we propose chemical site-specific pyrophosphorylation of proteins using - “tag-and-modify” approach. It relies on expression of protein bearing cysteine in the position of interest. The cysteine is then chemically converted to dehydroalanine (“tag”), which reacts with various sulphur or carbon nucleophiles under mild - conditions to introduce pyrophosphate PTM mimics (“modify”). The method allows preparation of not only pyrophosphorylated proteins, but also their phosphatase resistant analogues. These will be invaluable for mechanistic studies of - pyrophosphorylation reversibility and its biological role. As a proof of concept, well defined chemically pyrophosphorylated transcriptional factor GCR1 will be prepared by proposed strategy. The influence of GCR1 pyrophosphorylation on interaction - with GCR2 will be explored, since this is assumed to control transcription of glycolytic genes in yeast. Our new technique for the site-specific chemical synthesis of pyrophosphoproteins will provide long awaited tool to gain a better understanding - of the physiological role of this novel PTM. - - 2018-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - PyroPhosphoProtein - - - H2020-MSCA-IF-2015 - - - 700124 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 270 271,80 - - - Application of peptide screening technology for identification of substrates of the Jumonji-C histone demethylases - - - EUR 270 271,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - In recent years it has become evident that the functional human proteome is vastly expanded by post-translational modifications (PTMs) that modify protein function and gene expression in a time- and context-dependent manner. - Misregulation of these modifications leads to developmental disorders and often contributes to disease biogenesis. However, with the possible exception of protein phosphorylation, the full roles and regulation of these modifications remain poorly - understood. Currently, in particular, arginine methylation is proposed to be largely stable and irreversible. Building on my exciting preliminary data that demonstrate that Jumonji C histone demethylases (JmjC KDMs) can catalyse removal of arginine - methylation, this proposal aims to identify biologically relevant methylarginine substrates of the JmjC KDM. Cutting-edge mRNA display-based peptide screening technology will be adapted for use as a substrate identification assay in collaboration - with Prof Hiroaki Suga at the University of Tokyo. Consensus sequences identified using this novel methodology will be used to identify biologically relevant peptide sequences by bioinformatic searches. On the return to the UK, results with isolated - proteins will be correlated with in-cell studies and the functional consequences of these reactions assessed. Given the high level of interest in the post-translational modification field, the results of this study will be of interest to a very - wide-range of scientists including other academic researchers in the field of epigenetics and beyond, and major biotechnology and pharmaceutical companies studying JmjC KDMs as drug targets. The fellowship will provide training in state-of-the-art - techniques. The collaboration between the University of Oxford and the University of Tokyo will enhance the research capabilities of the European Union, promote cross-fertilisation of knowledge and strengthen research ties with Japan. - - 2018-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - RAPID-KDM - - - H2020-MSCA-IF-2014 - - - 657292 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 195 454,80 - - - Development and in situ Infrared study of Novel Strained Core-shell Electrocatalysts: Towards an Understanding of the Oxygen Reduction Mechanism - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The oxygen reduction reaction (ORR) is critical in fuel cells (FC), batteries and corrosion. Sluggish kinetics of the ORR remains a key barrier to efficient electricity generation in FC operating on renewable fuels such as - hydrogen or alcohols. Poor understanding of the ORR mechanism has hindered development of cost-effective and improved FC catalysts. - - - 2017-03-31, closed project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ORRmetIR - - - H2020-MSCA-IF-2014 - - - 659306 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 183 454,80 - - - Experiences and Memories of French and Algerian Veterans. Remembering the 'petite guerre' in the Aurès-Nememcha - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The present study aims to investigate the Algerian War of Independence (1954–62) from a new perspective. It proposes to frame a transnational history of the war, going beyond both the (opposing) French and Algerian (national) - narratives, to resituate the war in its Mediterranean, European, and eventually its global contexts. This general research objective, however, will be achieved by using a microhistorical approach: instead of looking at the conflict as a generic - “whole” and examining its reverberations in an elusive “collective memory”, the project focuses on a specific region, the Aurès-Nememcha in the Algerian south-east. At the core of this project are the specific experiences and memories of French and - Algerian veterans who fought each other for eight years, in this mountainous, Berberophone area. Who were they? What kind of war were they fighting, and why? And fifty years after the ceasefire, how do the citizens of each country cope with their - combat memories? The project will mobilise a wide range of sources, mostly but not exclusively French and Algerian. Aiming to analyse both past events and their present memories, this study will rely on both qualitative and quantitative analytical - methods, in a truly interdisciplinary framework. Indeed, this “global microhistory” approach—beyond being an original contribution to historical research—aims to offer new knowledge of and insights into the Franco-Algerian War, in order to help the - two countries to go beyond the narrow national narratives that continue to fuel an unexhausted “memory war” that is ongoing both between and within Algeria and France. If the efforts of the EU and the Union for the Mediterranean (2008) may help to - set a new tone in the near future, today it is less at the state level that it is possible to act than at the level of the people, by focusing on their particular and familial stories. - - 2017-08-31, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - PETITE GUERRE - - - H2020-MSCA-IF-2014 - - - 656782 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 183 454,80 - - - The Role of Adipose-Tissue Derived wnt-ligands in the Regulation of Myocardial Redox Signalling - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Myocardial redox signalling is a critical regulator of myocardial physiology and a therapeutic target in cardiovascular science, while obesity seems to trigger myocardial oxidative stress. The non-canonical wnt signalling - pathways (Ca2+-dependent (CDP) and planar cell polarity pathway (PCP)) are important in cardiac development and they are also involved in obesity (wnt ligands are involved in adipose tissue expansion), although their role in the adult myocardium is - unknown. We propose to define the role of CDP and PCP in the regulation of myocardial redox state in the human adult heart. We will perform a) Clinical association studies using tissue from patients undergoing cardiac surgery to test for paracrine - effects of adipose tissue on myocardial PCP/CDP regulation b) Studies using ex vivo models of human myocardium (trabeculae) to test the role of CDP/PCP in myocardial redox state regulation c) Cell culture studies using primary human cardiomyocytes to - explore the mechanisms of these effects d) Animal studies using a novel transgenic mouse model to test causality of the associations. In this translational study we will explore for the first time the role of CDP/PCP in the regulation of myocardial - redox signalling and evaluate its role in cardiac physiology. This work may identify novel disease biomarkers and therapeutic targets for the treatment of myocardial diseases. - - 2017-06-30, closed project | - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - REDOxHEART - - - H2020-MSCA-IF-2014 - - - 656990 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 195 454,80 - - - Sustainable Mixed-ion Layered Perovskite Solar Cells - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - We propose to create and investigate new types of organic-inorganic perovskite materials for low-cost solar cells. The state-of-the-art perovskite based solar cells employ MAPbI3, which has raised concerns over the potential - toxicity of Pb. The strategy of the MPerS project is to create, investigate and optimise sustainable perovskite materials for solar cell application. More than one types of metal and organic ions will be introduced in the perovskite structure to - realize layered materials which are expected to exhibit both excitonic and free carrier behavior with enhanced stability. Thin films of the new materials will be characterized using several techniques, e.g. Xray diffraction. THz, Time resolved - emission spectroscopies, EBIC will be used to understand the generation and dynamics of charge carriers in the materials and across interfaces. Development of solar cells will be carried out with an aim to reach 15% power conversion efficiency - employing a non-toxic absorber. This highly interdisciplinary project that spans the field of chemistry, condensed matter physics, electronics and engineering is conceived on basis of the combined expertise of the host and the applicant and - state-of-the-art infrastructure at the UOXF. A secondment at Oxford PV will test the commercial viability of the project. This project addresses Horizon 2020’s goals on clean and sustainable energy and the EU’s concern on toxicology of Pb . - Completion of the project will open up new areas in low-cost electronic materials with wider impact and improve EU’s competitiveness in materials research. While the applicant will get an opportunity to learn new experimental skills in condensed - matter physics and spectroscopy and benefit from industrial exposure. UOXF will benefit from the applicant by using his skills and broader broader collaboration with leading researchers in materials science. A plan is also proposed to carry out - public engagement, dissemination and commercial exploitation. - - 2017-03-31, closed project | - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - MPerS - - - H2020-MSCA-IF-2014 - - - 653184 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 251 857,80 - - - Organic-Inorganic perovskite and organic semiconductor films with improved crystal properties via reel-to-reel solution coating; application to photovoltaics and field effect transistors - - - EUR 251 857,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - This project will develop low cost and scalable solution–based coating techniques to yield electrically tunable films with macroscopic crystalline domains of both organic–inorganic perovskite and organic semiconductors. These - layers will be used to prepare solution processed hybrid perovskite-based photovoltaic (PV) devices surpassing 20 % solar-to-electricity power conversion efficiency, to provide a low cost and renewable energy supply. The researcher will carry out the - processing and characterization of the materials at Professor Zhenan Bao's laboratory at Stanford University. Professor Bao is a world leader in using solution deposition techniques to tune the physical and electronic properties of solution-processed - semiconductors for use in FETs, and is well suited to extend this approach to perovskite PV. The skills and knowledge obtained at Stanford University will be brought back to Professor Henry Snaith's laboratory at Oxford University and to Oxford - Photovoltaics ltd to prepare low cost, scalable perovskite PV with enhanced macroscopic crystal properties and performance. Professor Snaith is recognized as one of the pioneers in perovskite based PV, and is thus excellently placed to guide the - researcher in the development of PV with superior performance for eventual employment as large-scale energy supply. This project will form a unique union of two world leading research groups with complementary expertise. There is great potential for - the transfer of skills, generation of intellectual property, and industrial involvement within the EU via the ISIS program at Oxford University, and the company Oxford Photovoltaics of which Professor Snaith is the CTO. - - 2018-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - Crystal Solar - - - H2020-MSCA-IF-2014 - - - 659225 - - - - - MARTIN-LUTHER-UNIVERSITAET HALLE-WITTENBERG - - - EUR 159 460,80 - - - Using Land Cover Change Models to Address Important Conservation Issues - - - EUR 159 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - Anthropogenic land use/land cover change (LULCC) is now one of the major causes of biodiversity loss and the second largest source of carbon emissions to the atmosphere. Policy-makers face a challenging task when making - decisions that impact the future of the landscapes with great levels of uncertainty about its outcome. Spatially-explicit LULCC models can be important tools to help assessing the outcome of such decisions a piori. However, modelling anthropogenic - processes is a great challenge. Not only is the physical environment itself highly variable, but the underlying processes that drive LULCC combine socio-economic, cultural, political and environmental factors. Although enormous advances have been - made in the field of LULCC modelling over the past couple of decades, there is room for improvement as these models still lack the ability to project both the rate and location of future change accurately. Improving these models would dramatically - increase their potential to help solving real-world problems. Therefore, this research proposal will improve an existing LCCM to be able to incorporate region- and land-use transition specific parameters, representing observed relationships between - proximate causes and drivers of LULCC, which vary over time and space. By the means of two real-world case studies, on different biomes (Serengeti-Mara Ecosystem and the Brazilian Atlantic Forest), this project will show how a LULCC model can be used - to tackle two important worldwide conservation issues: the conflict between infrastructure development and conservation (Serengeti) and the impacts of implementing financial incentives to promote forest restoration (Atlantic Forest). Ultimately, this - research proposal will provide a framework for robust decision-making under uncertainty, particularly when considering potential trade-offs between socio-economic and ecological implications at different scales, and a tool for aiding management of - stakeholders' conflicts due to LULCC. - - 2018-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - LCCMcons - - - H2020-MSCA-IF-2015 - - - 703862 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 195 454,80 - - - Multiscale dynamics of astrophysical plasmas: pressure-anisotropy-driven instabilities and large-scale dynamical processes - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The primary purpose of the proposed project is a deeper understanding of instabilities in plasmas and their influence on transport phenomena and large-scale dynamical processes. The studies will be focused on nonlinear regime - of development of the firehose and mirror instabilities triggered by pressure anisotropy spontaneously generated in stellar-wind environments by large-scale expansion/compression effects and plasma turbulence. Recent studies of microphysics of the - instabilities have provided systematic knowledge on saturation effects in nonlinear regime and related wave-particle interactions. This opens a possibility of investigation of a feedback between the microphysics and large-scale dynamics. The project - is anticipated to provide answers to the questions: what is the effective collisionality of a pressure-anisotropic plasma that is unstable or marginally stable to the firehose and mirror instabilities and how does it change the effective pressure - tensor (viscous stress) used in fluid description of plasmas? - - 2017-05-31, closed project | - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ASTROMULTISCALE - - - H2020-MSCA-IF-2014 - - - 657251 - - - - - UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6 - THE UNIVERSITY OF EDINBURGH - NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU - TECHNISCHE UNIVERSITEIT DELFT - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - SCHLUMBERGER CAMBRIDGE RESEARCH LIMITED - - - EUR 3 227 952,96 - - - Waves and Wave-Based Imaging in Virtual and Experimental Environments - - - EUR 3 227 952,96 - - - France - United Kingdom - Norway - Netherlands - United Kingdom - France - France - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Demand for highly trained scientists with a deep understanding of wave propagation in complex media, and capable of exploiting this knowledge to develop imaging tools for seismology and acoustics, is very high in the Earth and - environmental sciences. Wave-based imaging serves to map spatial and temporal variations in the structure of the Earth's interior, of the oceans and atmosphere; it is used to monitor faults and volcanoes and detect natural-resource reservoirs. It is - relevant to other disciplines, medical imaging being one of its most widespread applications. Today’s Earth scientists are faced with a set of questions that require the application of wave-based imaging at unprecedented resolution. WAVES aims at - fostering scientific and technological advances in this context, stimulating knowledge exchange between seismologists and acousticians, and researchers in the public/private domains. A unique strength of our network resides in the participation of - novel physical acoustics laboratories, managed by beneficiaries/partners of WAVES, with a strong record of experimental research on inter-disciplinary and seismology-related topics. WAVES will train young scientists working in academia or industry in - how to use this resource effectively, re-introducing the laboratory into the ideas-to-applications pipeline. Experimental work will serve to develop new theory, addressing topics of current interest such as acoustic time-reversal, scattering-based - imaging. A truly multidisciplinary network, WAVES will apply these new ideas in a number of contexts: medical elastography is used as a tool to implement novel analogue models of seismic faults; wave sources are localized by a bio-inspired system - making use of very few receivers, etc. Through WAVES, a critical mass of expertise will consolidate, defining the study of acoustic/elastic wave propagation and wave-based imaging/monitoring as an independent discipline, rich in applications of - intellectual and societal relevance. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - France - - - WAVES - - - H2020-MSCA-ITN-2014 - - - 641943 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 226 825,20 - - - Artificial Tissue Actuators by the 3D Printing of Responsive Hydrogels - - - EUR 226 825,20 - - - United Kingdom - - - Higher or Secondary Education Establishments - - This proposal describes the 3D printing of hydrogel droplet networks to prepare artificial tissue-like materials that demonstrate stimulus-responsive chemo-mechanical actuation. A recent breakthrough by Prof. Bayley’s research - group has enabled the 3D printing of self-supporting droplet networks which can be functionalised to allow rapid electrical and molecular communication along a specific path. As a result of this, an opportunity now exists to prepare tissue-like - materials that can perform mechanical work in response to external stimuli. By printing biocompatible and responsive polymer hydrogels into droplet networks, artificial muscles will be prepared that display specific and well-defined motion. The - resulting technology will be of great importance for a variety of biomaterial applications, with future European Union (EU) industrial growth as well as the public ultimately benefiting from progress in this area. - - 2017-12-31, closed project | - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - DLCHHB - - - H2020-MSCA-IF-2014 - - - 657650 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 149 983 - - - Perovskite Light Emitters - - - EUR 149 983 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Metal halide perovskites have recently astonished the research community and garnered a mass following to realize extremely high efficiency low cost photovoltaics. This work was largely catalyzed by outputs from the ERC-Stg - HYPER, but in addition to solar cell applications, these materials could also be near perfect light emission materials for displays and lighting. This POC grant will formulate a strategy to move the perovskite materials and device research towards - commercial exploitation as light sources. Within the project an assessment of the impact perovskite nanocrystals could have in the current lighting market will be undertaken, and a strategy to capitalise upon exiting Oxford IP and how best to develop - foreground IP will be formulated. To complement these activities, a demonstrator perovskite light source will be created. From the derived information on IP and business development, a business plan will be delivered which will be taken to the - investor community following successful completion of the POC project. This project will therefore enable the transition for perovskite light emitting nanocrystals from University research to a commercial venture. - - 2017-06-30, closed project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2015 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - PLE - - - ERC-2015-PoC - - - 693144 - - - - - FUNDACIO CENTRE DE REGULACIO GENOMICA - - - EUR 1 274 400 - - - CRG International Research Postdoctoral Programme - - - EUR 2 548 800 - - - Spain - - - Research Organisations - - INTREPiD is an innovative 5-year Fellowship Programme that aims at recruiting 12 experienced researchers at the Centre for Genomic Regulation (CRG) located in the Barcelona Biomedical Research Park (PRBB), one of the largest - biomedical research clusters in southern Europe. Fellows will be selected following an open, transparent, and merit-based process, based on international peer-review, and offered attractive working conditions in line with the European Charter and - Code (the CRG was awarded the HR Excellence in 2013). Selected researchers will be able to develop their own project under the supervision of the group leader they select. They will be offered international, interdisciplinary and inter-sectorial - mobility opportunities in a highly creative and dynamic environment supported by cutting-edge core facilities and a vibrant network of collaborators from academia and the private sector. INTREPiD will provide tailored mentoring and a comprehensive - training programme, including up-to-date scientific and technological courses in a wide range of topics and disciplines, and modules on transferable skills, entrepreneurship, open science and career development. Mobility to national and international - academic and non-academic institutes will be encouraged, in one of the partner organisations or in institutes that research labs collaborate with. Overall, the INTREPiD Programme will provide fellows unique skills and competences for developing a - successful career in both the academic and non-academic sector. Thanks to the large CRG network of collaborators locally and internationally, the Programme will also catalyse sharing of best practice in experienced researchers training programmes - across different institutes. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.4."> - - - MSCA-COFUND-2016 - Co-funding of regional, national and international programmes - - - MSCA-COFUND-FP - Fellowship programmes - - - Spain - - - INTREPiD - - - H2020-MSCA-COFUND-2016 - - - 754422 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 150 000 - - - Cost efficient thermal management in motors using next generation nanomaterials - - - EUR 150 000 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Electric motor drives are the universal work horses of industry driving fans, pumps, power tools, compressors and materials handling/conveyor systems. More energy efficient motor designs are needed to meet increasingly - stringent EU efficiency standards. Better thermal management of electric motors could make this achievable. Current technologies rely on expensive copper casings or inefficient air cooling. Adding more copper is not feasible (bigger, heavier and - expensive) and liquid cooling is not attractive (more energy for circulation/maintenance). The extra mass/volume cannot be easily integrated in compact motor layouts. Removal of heat from small totally enclosed motors is a recurring problem in the - food processing, surgical instruments and materials handling where the motors operate at their limits and run very hot. An improved method of cooling could be engineered from advanced materials. Nanomaterials such as carbon nanotubes are at least six - times more thermally conductive than conventional thermal interface. A commercial application using specially tailored carbon nanotubes (CNTs) for the development of energy-saving, highly efficient motors is the aim of CONDUCT in partnership with an - EU SME motor design/manufacturer. Results of CONDUCT will feed into advanced automotive, consumer, and power electronics industries who also need to find solutions for similar challenges in thermal management. - - 2017-07-31, closed project - - - 2016-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2015 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - CONDUCT - - - ERC-2015-PoC - - - 680559 - - - - - AARHUS UNIVERSITET - - - EUR 200 194,80 - - - The BV Construction: a Geometric Approach - - - EUR 200 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - The BRST (Becchi-Rouet-Stora-Tyutin) cohomology plays a very important role in facing the problem of quantizing non-abelian gauge theories via the path integral approach. Indeed, this quantization procedure fails when applied - to gauge theories, due to the presence of local symmetries in the action. This problem is overcome by introducing extra (non-physical) fields, defining a so-called BRST cohomology complex. It is precisely this cohomology that allows the recovery of - important information on the theory, such as its set of observables or its renormalizability. Despite of its relevance in the context of quantum fields theory, this cohomology still deserves to be fully understood from a mathematical/geometrical - point of view. As I discovered in my PhD thesis, a very promising approach to reach this goal is to try to insert the BRST cohomology (constructed following the Batalin-Vilkovisky (BV) approach) in the framework given by Noncommutative Geometry - (NCG). In this project I will continue along this line of research by focusing on the case of finite-dimensional gauge theories. Indeed, this context has shown to be surprisingly rich for the analysis of the BV formalism, due to the emergence of a - peculiar phenomenon, not appearing in the infinite-dimensional case: the infinite ghosts-for-ghosts. Even though since the discovery of NCG it is known its strong connection with gauge theories, the idea of using NCG as a mathematical framework to - formalize the BV construction and the BRST cohomology is still an unexplored territory. The credibility of this approach has been proved by some preliminary results I obtained for U(2)-gauge theories. Moreover, since NCG gives a common tool (the - notion of spectral triple) to study both finite and infinite-dimensional gauge theories, the results obtained with this project will be a fundamental starting point for further research: they will point the way to investigate the BV construction also - for gauge theories on a 4-dim spacetime. - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - BVCGA - - - H2020-MSCA-IF-2016 - - - 753962 - - - - - UNIVERSITY OF GLASGOW - - - EUR 183 454,80 - - - Multi-driver climate change effects on SEAgrass METabolism: ecosystem implications - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Pressures linked to global climate change (GCC) (i.e. ocean acidification (OA), warming and hypoxia) represent a major threat for marine ecosystems. The single and combined effects of GCC drivers is expected to alter the - energetic costs of main metabolic routes, forcing trade-offs in organismal metabolism, with further impacts in the functioning of the whole ecosystem to which they belong. While we have an improving understanding of the impacts of single and paired - stressors on individual organisms in the laboratory, to determine real-world impacts of GCC we need to comprehend the impacts of multiple stressors on individuals, understand the acclimation and adaptation processes and assess the repercussion on the - ecosystems functioning. SEAMET addresses this major challenge in marine science by assessing if marine communities can survive under the multiple stressor future driven by GCC. SEAMET will use a key benthic habitat-forming species (seagrasses) as - model system employing net metabolic balance (NMB) as a functional trait to scale up implications of individual readjustments to GCC on the functioning of the whole ecosystem. It will determine i) the mechanistic basis that regulates C incorporation - and photosynthetic physiology, ii) the physiological plasticity and tolerance thresholds of organisms to different combinations of GCC drivers (OA, temperature (T) and hypoxia), and iii) the in situ acclimation and adaptation potential of organisms - and associated communities to GCC. SEAMET uses a novel multidisciplinary approach to ensure candidate training and the transfer of knowledge to the host institution. Internationally competitive outputs will be a direct contribution to European - MSFD2008/56/EC directive and Horizon2020 strategy for climate action providing novel insights into the effects of climate change on marine ecosystems and their functioning. - - 2020-01-07, ongoing project - - - 2018-01-08 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SEAMET - - - H2020-MSCA-IF-2016 - - - 752250 - - - - - UNIVERSITY OF GLASGOW - - - EUR 195 454,80 - - - Electroactive Materials based Bandage for Accelerated Wound Healing - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Wound healing can be accelerated by using wound dressing impregnated with biochemical agents and biophysical methods such as electrical stimulation (ES). The current ES technology is complex, non-portable, costly and requires - external power. ELECTROHEAL is planned to develop a simple, cost effective and disposable wound dressing or bandage to accelerate the wound healing process. - - 2019-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ELECTRO-HEAL - - - H2020-MSCA-IF-2016 - - - 753633 - - - - - UNIVERSITY OF GLASGOW - - - EUR 269 857,80 - - - The Social Anthropology of Rabies Epidemiology and Elimination - - - EUR 269 857,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Rabies is a viral disease transmitted to humans through the bite of rabid animals, predominantly domestic dogs. It is ranked among the highest priority zoonotic neglected diseases by major international human and animal health - organizations (the World Health Organization and World Organisation for Animal Health) and its control is considered a global public good. Although rabies is preventable through administration of post-exposure prohylaxis to individuals exposed to - suspect rabid bites and mass vaccination of dogs, the disease still kills thousands globally. India has the highest number of rabies deaths in the world for reasons that are likely to be as much socio-cultural as they are biological, although these - factors have neither been investigated nor integrated with epidemiological data. In India, I will focus on two contrasting (based on linguistic, cultural and religious background) rural areas of Gujarat and Maharashtra, where rabies is very - prevalent. I will first investigate cultural and religious aspects shaping attitudes towards dogs and local-level acceptance of rabies control and prevention measures, including dog vaccination and human rabies prevention. I will subsequently explore - the feasibility and acceptability of in-depth epidemiological data collection tools, contact tracing, to understand cultural and religious influences on people’s health seeking behaviour, practices that may lead to increased rabies risks, and - management of these risks within this particular socio-cultural context. Data gathered in this preparatory phase will ultimately inform the design of culturally acceptable and integrated One Health interventions that will to contribute to reduced - rabies exposures and mortality. Together with these expected health benefits, my project will demonstrate the added value of One Health, interdisciplinary, approaches to the study and management of zoonoses, and will therefore address an evidence gap - of global health relevance. - - 2020-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - SAREE - - - H2020-MSCA-IF-2016 - - - 751267 - - - - - AARHUS UNIVERSITET - - - EUR 212 194,80 - - - Sustaining A Regional Screen Ecosystem In A Small Nation: Aarhus and the West Danish Film Fund, 2002-2019 - - - EUR 212 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - Since 2010 Danish screen production has enjoyed international attention with the popularity of high-quality films and TV series. Yet these emerge from a specific culture-political milieu that is concentrated in the capital - Copenhagen. Current research on Danish production is similarly Copenhagen-centric. This imbalance means that peripheral regions of Denmark like Aarhus are neglected and underdeveloped as production hubs. This project addresses the question of how - regional screen industries of small nations can be sustained and strengthened by examining the site-specific activities of the West Danish Film Fund (DVF) and its collaborations with the Aarhus 2017 EU Capital of Culture project. My main objectives - are to 1) produce a 'deep map' of the regional screen ecosystem in Aarhus, 2) identify the implications of new funding and support initiatives, and 3) outline strategies on how regional screen production can productively harness geography, heritage, - and tourism to strengthen domestic and international ties. I utilise a combination of qualitative and quantitative methodologies in screen studies to achieve these goals. Through a 4-week secondment at DVF and close links between Aarhus University - (AU) and industry players, I will interview screen practitioners and policymakers across the region, examine policy and funding practices, analyse quantitative data relating to production and distribution, and evaluate industry innovations. This - project includes both transfer of knowledge to AU and the training of the candidate in advanced techniques. This interdisciplinary research will be the first to significantly deepen knowledge on the regional screen industry of Aarhus and provide - policy advice, build networks, concepts and tools on how to sustain the regional screen milieu. Results will have strong applicability to other Capitals of Culture and EU regions, enhancing understanding of how regional screen industries balance - national cultural policy with local identity. - - 2020-04-30, Grant Agreement signed - - - 2018-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - SARSESNA - - - H2020-MSCA-IF-2016 - - - 753597 - - - - - KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN - - - EUR 159 460,80 - - - Deciphering causes and consequences of inflammation in subtypes of sporadic intestinal cancer - - - EUR 159 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - An association between inflammation and carcinogenesis is well established, however, how they are related mechanistically in subtypes of sporadic intestinal tumours remains unclear. This study aims to decipher how oncogenes - determine the inflammatory microenvironment (stroma) and how this affects tumour development and survival. Notably, intestinal epithelium-specific expression of oncogenic Kras(G12D), Braf(V637E) and Pik3ca(H1047R) in mice mimics serrated intestinal - cancers in humans faithfully. Preliminary data suggest that the mutational make-up of the tumour may dictate the pro- and anti-tumourigenic immune response, which in turn determines tumour development and survival. This study therefore aims to - characterise the tumour-infiltrating immune cells by systematic immunophenotyping and to decipher the involved inflammatory signalling mechanisms in a cell-type and mutation-specific manner. Moreover, we aim to reconstruct the formation of the - oncogene-specific inflammatory microenvironment, which we will determine via endoscopic transplantation of intestinal organoids derived from Kras(G12D), Braf(V637E) and Pik3ca(H1047R) mice into the large intestine of wild-type mice. Importantly, - detection of involved inflammatory mediators and immune cell-subtypes will allow us to genetically target them in vivo using novel in-house generated dual-recombinase systems (DRS). In order to investigate the consequences of inflammation on sporadic - intestinal tumourigenesis, models with genetically or experimentally induced chronic inflammation will be applied. Conversely, immunodeficient Rag2;Il2rg–/– mice will be used to elucidate if sporadic intestinal carcinogenesis in Kras(G12D), - Braf(V637E) and Pik3ca(H1047R) mice is dependent on inflammation and can be abrogated. This study will generate new mechanistic insights into the microenvironment of cancer subtypes, which could provide a basis for the development of new personalised - immune therapies. - - 2020-02-14, Grant Agreement signed - - - 2018-02-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - DSMT16 - - - H2020-MSCA-IF-2016 - - - 753058 - - - - - ASTON UNIVERSITY - - - EUR 195 454,80 - - - Optical transmission based on integrability and nonlinear Fourier transform - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - "Optical fibre systems form the backbone of global telecommunication networks and carry the bulk of the world's data traffic, serving as a key component of information and communication technology. Although over the years, - these systems have become increasingly complex, the quality of optical system performance is still affected by the same key physical features: chromatic dispersion, fiber Kerr nonlinearity, and optical noise. Most of the current optical networks - exploit the techniques that were originally developed for linear channels. Thus, it is not surprising that nonlinearity has a detrimental impact on such systems. It has been predicted that, within the next decade the existing optical fibre technology - will approach the "nonlinear transmission limit", which caps the achievable rate of error-free data transmission. Thus, in order to reach a the higher capacity of optical fibres it is necessary to shift the relevant information and communications - technology paradigm by introducing truly nonlinear modulation, transmission, and signal processing techniques. The aim of this project is to develop ground-breaking visionary concepts and approaches to unlock the capacity of fiber-optic - communications beyond the limits of current technology by treating optical fiber as the inherently nonlinear medium it is. Our paradigm-shifting approach is based on the concept mathematical notion of integrability and the related nonlinear Fourier - transform-type processing of optical signal, which allow us to use of the fibre nonlinearity in a constructive way. This multidisciplinary project, grouping together the mathematical theory of intergability, advanced signal processing, the physics of - nonlinear waves evolution, solitons, and noise interaction with nonlinear excitations, combined with the optical transmission methods and purposes, is aimed at the development of fundamentally new communication technologies to satisfy current and - future technology challenges." - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - OMICRON - - - H2020-MSCA-IF-2016 - - - 751561 - - - - - UNIVERSITE LYON 1 CLAUDE BERNARD - - - EUR 173 076 - - - NLRP3 in cancer: Deciphering the role of NLRP3 in the DNA Damage response pathway - - - EUR 173 076 - - - France - - - Higher or Secondary Education Establishments - - Cancer represents one of the main causes of death in the European Union (WHO). Particularly, non-small-cell lung cancer (NSCLC) accounts for 85% of lung cancers, and is the leading cause of cancer-related death worldwide. - Despite significant therapeutic improvements, the survival rate of patients with advanced stage NSCLC remains dismal, signifying a critical need to elucidate the molecular processes driving NSCLC. Inflammasomes are major drivers of inflammatory - responses and are deregulated in a wide range of disorders, yet their participation in carcinogenesis is largely unknown. Genome analyses reported that the NLRP3 receptor, component of the NLRP3 inflammasome, is affected by somatic alterations in 20% - of NSCLC. Moreover, recent evidence has shown that NLRP3 is essential for the activation of the ATM/CHK2 pathway in response to double strand breaks (DSBs), while its expression is systematically absent in NSCLC cells. Based on these data, we - hypothesize that NLRP3 is a key factor in the DDR pathway to DSBs and in the maintenance of genome integrity in lung epithelial cells, and as a consequence may play a key tumor suppressor role. The objectives of RoNDBioCan will be to decipher the - molecular mechanism of NLRP3 function in the DDR pathway and to evaluate the therapeutic potential associated with NLRP3 expression. By characterizing novel NLRP3 partners and examining the impact of NLRP3 re-expression on tumor development in vivo, - RoNDBioCan will significantly improve the current knowledge regarding NLRP3 participation in lung cancer. Given that the poor outcome associated with NSCLC is mostly due to limited curative options, there is an urgent need to identify new biomarkers - and additional treatments to reduce the current burden of lung cancer. This work will thus considerably contribute to the development of new effective and personalized therapeutic approaches to help improve the prognosis of lung cancer patients. - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - France - - - RoNDBioCan - - - H2020-MSCA-IF-2016 - - - 751216 - - - - - THE UNIVERSITY OF BIRMINGHAM - - - EUR 183 454,80 - - - Silicon Cluster based Hierarchical photocatalysts produced by MATrix assembly cluster source - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Photocatalysis is important for solving the worldwide energy shortage and environmental pollution issues. Recently, silicon materials are considered to be promising catalysts. In particular, size controlled Si - clusters/nanoparticles/QDs show tunable emissions/absorption from near infrared to blue wavelength, making them promising candidates as photocatalysts. However, the research on the Si clusters based photocatalysts is still slow progress due to - lacking of methods of fabrication of Si clusters with precision and in large quantities. In addition, unlike the widely studied Au and Ag nanostructures, which have distinct and well-defined SPR absorption peaks , small (<10nm) Si nanoparticles - always exhibit low extinction from the ultraviolet to short wavelength of visible light, and thus result in lower photocatalytic efficiency. In SCHiMAT, the luminescent, photoelectric and photocatalytic properties of Si clusters with precisely - controllable size and high production, which produced by “Matrix Assembly Cluster Source” (MACS), will be systemically studied. Based on that, this project will entail the design of a novel kind of hierarchical structure, which involves the choice of - spherical semiconductor nanoparticles (SiO2, Al2O3, ZrO2, TiO2 CeO2 and ZnO NPs) and distribution modulation of the Si QDs on the semiconductor support, to largely enhance the photocatalytic efficiency of Si QDs, which is distinct from a conventional - photocatalytic efficiency enhancement strategy aimed at exciting surface plasmon by means of incorporating metal nanostructures. This project would open a promising new route to using Si cluster/QDs as visible-light absorber for solar energy - conversion. The project combines ER and host supervisor’s expertise in nanocluster, photonics, catalysis research, and will equip the ER to carry out cutting edge research in cluster-based nanomaterials and photocatalysis. - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SCHiMAT - - - H2020-MSCA-IF-2016 - - - 752102 - - - - - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - - - EUR 175 419,60 - - - Quantitative super-resolution optical fluctuation and phase microscopy for structural and functional imaging of Parkinson's disease - - - EUR 175 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - The changing demographic is one of the greatest challenges in Europe. With an expected 25% of the population over 65 by 2030, the incidence of neurodegenerative age-linked diseases like Alzheimer’s and Parkinson’s is likely to - increase. They severely impact quality of life and to date, therapies can only treat the symptoms. Oligomerization and aggregation of the protein α-synuclein is a hallmark of Parkinson’s disease. Still, the underlying molecular mechanism of cellular - dysfunction due to toxic forms of this protein remains unclear. Most studies aiming to uncover α-synuclein induced neurodegeneration in vivo are using indirect biochemical detection methods. Bridging neurobiology and life science with advanced - microscopy and image analysis allows the direct monitoring of Parkinson compromised primary hippocampal neurons. I will combine multi-color 3D super-resolution optical fluctuation imaging with quantitative phase tomography in a multi-plane - microscope, to allow structural and fast functional imaging. This innovative imaging concept is used (1) to elucidate α-synuclein aggregation at the cell membrane and in the cytosol and (2) to uncover the induced cytoskeleton alterations. Ultimately, - molecule-specific readout will be complemented by (3) label-free, quantitative phase imaging of membrane dynamics and overall cell morphology at up to 100Hz. I am a biophysicist with a specialization in single molecule spectroscopy and my previous - work on photon statistics has led to several high quality publications. This fellowship expands my quantitative microscopy expertise to 3D imaging while enlarging my biologocal scope to neurodegenerative diseases. I will extend my competences by - managing the project, following complementary skills courses, and organizing public outreach activities. While performing interdisciplinary research on neurodegenerative disease, I will develop an independent research profile to further enhance the - European research landscape. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - funcSOFI-PD - - - H2020-MSCA-IF-2016 - - - 750528 - - - - - UNIVERSITY OF STRATHCLYDE - - - EUR 183 454,80 - - - Multi-scale computational hemodynamics in obese children and adolescents: enabling personalised prediction of cardiovascular disease - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Childhood obesity is currently at epidemic rates, with serious risks for cardiovascular disease in adulthood and premature death. Obesity is known to accelerate the initiation of endothelial dysfunction and alter the - hemodynamics in young arteries. In alignment with urgent EU and worldwide policies on understanding childhood adiposity, we propose to develop a novel and safe computational tool to study numerically, for the first time, the obesity-altered - hemodynamics in children and adolescents. The project aims to transfer the non-invasive computational fluid dynamic technology to the paediatric practice and enable personalised prediction of cardiovascular disease and effective decision-making. - Within a multi-scale modeling framework, the proposed study seeks to utilise high-fidelity state-of-the-art numerical methods and develop new ones, for the implementation and coupling of the 3D flow in anatomically realistic arterial geometries with - macroscopic and microscopic information, ensuring high stability and accuracy of results. In conjunction with clinicians, the study will perform patient-specific numerical simulations, correlated with medical data, and help towards individualized - treatment planning, with a significant impact on the quality of life of the young patient. This multidisciplinary perspective is fundamental in elucidating early vascular changes induced by obesity and predict cardiovascular disease risks, while - protecting the young population. - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - CALLIRHEO - - - H2020-MSCA-IF-2016 - - - 749185 - - - - - UNIVERZITA KARLOVA - - - EUR 154 720,80 - - - Evolution and development of pharyngeal pouches and pre-oral gut in basal fishes - - - EUR 154 720,80 - - - Czech Republic - - - Higher or Secondary Education Establishments - - Vertebrates, which include our own species, are the most diverse and successful group of Deuterostomes. Success of this group has been explained by the evolution of elaborated head skeleton adapted to capturing and processing - large prey. Most of this skeleton derives from neural crest cells migrating into the pharynx during and after the formation of pharyngeal pouches. To better understand how development of these structures evolved, the research project will study - representatives of three basal fish lineages that occupy key positions in jawed-vertebrate phylogeny. It will employ methods of genomics, gene expression, and gene manipulation including CRISPR/Cas9 gene editing system to test a mechanistic model of - pouch formation and its relationships to pre-oral endoderm development. The proposal builds upon the Fellow’s research of jawed and jawless vertebrates and bridges a gap in our knowledge of the pharyngeal evolution between the jawed and jawless - vertebrates and at the same time between vertebrates and their chordate and deuterostome ancestors. Two-way knowledge transfer is a crucial feature of this project: the Fellow will take advantage of the proficiency of the Supervisor and the - Department in embryology, morphology, manipulation, and husbandry of the rare basal fishes and in the genomics and transcriptomics, while at the same time he will transfer his expertise in genetic regulation of development and CRISPR/Cas9 gene - editing in non-model organisms to the Supervisor and Host Institution. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Czech Republic - - - Pharynx2016 - - - H2020-MSCA-IF-2016 - - - 751066 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 173 076 - - - Investigation of 3D Functional Connectivity in Mouse Visual Cortex using Holography and Optogenetics - - - EUR 173 076 - - - France - - - Research Organisations - - Cortical neurons respond selectively to sensory features. In mouse visual cortex, convergent evidences point towards stronger connectivity between neurons sharing similar feature selectivity in the superficial layers. The - relationship between a three-dimensional (3D) subnetwork, where neurons connect horizontally and vertically to each other, and the functional specificity of individual neurons remain however unresolved. The main objective of this interdisciplinary - project is to uncover the 3D functional connectivity in mouse visual cortex in vivo by employing the innovative optical methods pioneered in the host laboratory. Single-cell activation deep into the brain will be, for the first time, enabled using - the novel technology of 3D depth-resolved holographic light-patterning and two-photon optogenetics. Combined with whole-cell recordings for measuring postsynaptic responses, precise presynaptic excitation with holography will permit mapping - connection pairs within and across cortical planes. Simultaneous presynaptic multi-cell excitation of connecting neurons will test the integration linearity of the postsynaptic neuron. To probe functional connectivity, connection pairs will be - examined from a functionally-identified neuronal population, whose tuning specificity to visual attributes is determined using calcium imaging. This fellowship will render me opportunities to acquire a versatile optical toolbox that is of general - interest in neuroscience for connectivity mapping and circuit manipulation. Knowledge of local functional connectivity spanning a 3D cortical volume will further provide significant insights into the network mechanism underlying sensory processing. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - 3DMUCHO - - - H2020-MSCA-IF-2016 - - - 747598 - - - - - UNIVERSITY OF KENT - - - EUR 195 454,80 - - - Understanding children's empathy: an ethnographic study among the indigenous Runa of the Ecuadorian Amazon - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The phenomenon of empathy is receiving growing interest in the European public sphere and scientific community. In particular, the question of how one learns to feel empathy towards the environment and the beings which inhabit - it has been identified as a key issue to address at this time of environmental crisis.The proposed project investigates how empathy is learnt by children from an Amazonian indigenous community in Ecuador. It explores how and under what circumstances - indigenous children in the Ecuadorian Amazon learn to perceive nonhuman entities as human-like and develop empathy towards them. Grounded upon my extended ethnographic knowledge of the region, the project will contribute to broader contemporary - debates of how empathy towards nonhumans is culturally acquired, manifested and actively learnt during childhood. This is a social anthropology project with a strong interdisciplinary approach which includes perspectives from developmental - psychology, ecology, cognitive science and philosophy. The aims of this project are: 1. to explore how children learn to perceive others as human-like in a setting which is inductive to such learning; 2. to explore children’s perception and - understanding of nonhuman personhood and intentionality; 3. to understand the nature of ‘empathy’ among indigenous Runa people of the Ecuadorian Amazon. These aims will be reached through 10 months of ethnographic fieldwork in an indigenous Runa - village where I will deploy participant observation and other methodologies from psychology, medical and visual anthropology which will be designed during pre-fieldwork training at the University of Kent. Research results will be disseminated through - an academic and public engagement plan which includes two academic publications, an ethnographic film, a secondment at the Centre for Subjectivity Research in Copenhagen, a workshop and a document to be used by community members for school - policy-making. - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ChildEmp - - - H2020-MSCA-IF-2016 - - - 746363 - - - - - WISSENSCHAFTSZENTRUM BERLIN FUR SOZIALFORSCHUNG GGMBH - - - EUR 171 460,80 - - - CARe in an INterGenerational contextHow do changes in family formation trajectories reflect in later intergenerational relations? A three-generations perspective - - - EUR 171 460,80 - - - Germany - - - Research Organisations - - How do changes in early family formation trajectories reflect on later intergenerational relations and care support across generations? Early life choices in the process of family formation reflect in the availability of later - potential for care giving, or demands for it. CARING investigates the contribution of early family formation trajectories on explaining differences in intergenerational relations and support patterns later in life. Country differences in the - demography of family-linked life stages, and how these reflect on caring responsibilities, have remained largely unexplored. But the timing of family formation and dissolution, childbirth and grand-parenting are key transitions with bearing on - entitlements and obligations to inter-household (reciprocal) solidarity and support. To address these issues CARING will explore the effects of family diversification (childlessness, union dissolution and fertility postponement) on intergenerational - relations and support in 5 selected countries: Italy, Germany, France, Denmark and Czech Republic. Sequence analysis on data from SHARE surveys will compare family trajectories (partnerships and fertility over 34 years, at ages 16-49) for individuals - from the birth cohorts 1927-56. Family formation trajectories will contribute to the study of: current patterns of relations, upward support and downward support through hierarchical multinomial logit models. Results will be validated on fertility - trajectories for larger sample sizes and younger birth cohorts (1957-64). The project will adopt a comparative multi-generational perspective with a focus on three generations, helping shed light on the ‘caring potential’ for the new generations, - experiencing longer and thinner (beanpole) families and increasing rates of childlessness. CARING is relevant for the Pillar of Social Rights in the Work Programme and responds to the Europe 2020 strategy objective of an inclusive growth in face of - progressive aging in European societies. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - CARING - - - H2020-MSCA-IF-2016 - - - 749443 - - - - - OULUN YLIOPISTO - - - EUR 179 325,60 - - - Preserving Wooden Heritage. Methods for monitoring wooden structures: 3D laser scanner survey and application of BIM systems on point cloud models - - - EUR 179 325,60 - - - Finland - - - Higher or Secondary Education Establishments - - Wooden Heritage has been recognized today as an object of growing interest in scientific research even on international scale, not only from the architectural point of view but also from theoretical approaches. Over the times - many technological systems concerning timber have evolved, refined and defined in the use of mixed solutions. Wooden Architecture represents one of the oldest building systems adopted by the majority of people who developed construction techniques - respecting the local traditions. Today this vast and unique wooden heritage needs urgently survey and cataloguing. Fires and abandonment are the main factors jeopardizing the preservation of this architecture; every year too many wooden buildings - still disappear because of this negligence. This important challenge has the purpose to obtain new technical methods, procedures and protocols that don’t exist yet, fundamental for technicians and operators. The research project wants to address a - new scientific approach on wooden buildings. This is aimed for practical interventions for with respect to the scientific and epistemic foundations, by improving 3D laser scanner survey and photo-modelling activities through post production phases - with parameterization of the point cloud to create 3D digital models queried and enriched by informative content and increase BIM (Building Information Modeling) knowledge. The main and most important contribution of this project is the - accomplishment of scientific, technical and operational systems and tools for the documentation of wooden structures. During the process of analysis different experts belonging from the best host companies chosen, will guide, check and develop - jointly with the applicant all the methods, procedures and theoretical background for achieving the best results in a successful project. In this way the triangle Research-Theory-Practice will offer new insights to timber architecture, to the - preservation and maintenance of the wooden heritage. - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Finland - - - PresWoodenHeritage - - - H2020-MSCA-IF-2016 - - - 746215 - - - - - UNIVERSITEIT UTRECHT - - - EUR 165 598,80 - - - Global Transitions and Innovation Systems - - - EUR 165 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - World development is at a critical turning point. Globalisation has become ever more impactful. At the same time, we see a new long term industrial development cycle (or techno-economic paradigm; TEP) coming into full swing - that builds on Information and Communications Technology (ICT) while societies all over the world have to cope with sustainability challenges. These changes lead to a situation where industrial leadership may rapidly shift from one country to - another. Europe 2020 reckoned these challenges under its Flagship Initiatives, in particular “An industrial policy for the globalisation era’’. Drawing on scholarship from the field of Innovation Studies, GLOTRAINS aims to make major contributions to - the emerging global innovation system frameworks, combining literatures on industrial catch-up cycles and shifts in global leadership. More specifically, the project aims at further elaborating the Innovation System framework to encompass a - globalised and dynamic perspective, while asking whether and how national industrial policy can still play a decisive role. Empirically, this project focuses on both long and short cycle sectors to reflect the two main propositions of the TEP - hypothesis, i.e. the sustainability-driven clean-tech sector and the ICT sector. Both involve different types of catch-up mechanisms. Fieldwork cases are organised along a gradient of development stages represented by the countries of Germany, - China/Taiwan and Malaysia. The selection of these countries provides an excellent base to examine global catch-up cycles and industrial leadership shifts. The researcher has experience in both transition and catch-up studies, with fieldwork - experience in both long and short cycle sectors in China, Taiwan and Malaysia. - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - GLOTRAINS - - - H2020-MSCA-IF-2016 - - - 748922 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 173 076 - - - Micro-endoscopes for in-depth high-resolution optogenetics - - - EUR 173 076 - - - France - - - Research Organisations - - Understanding how the brain works is one of the grand scientific challenges of our times and constitutes a priority research line for the European Union. The study of the brain mechanisms that underlie fear learning and - response is particularly relevant as it could provide the key to control anxiety disorders, with an associated high social and economic benefit for the European community. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - ME-Optogen - - - H2020-MSCA-IF-2016 - - - 746173 - - - - - Roehampton University - - - EUR 183 454,80 - - - Barbara Bodichon's Epistolary Bildung - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Bildung is a controversial German neo-humanist term that, as conceptualised by Wilhelm von Humboldt (1767-1835), proposed a whole new educational project: to bring all the potential contained within each person to full - expression as a means towards social progress. Bildung is the object of renewed attention in theories of education today. While it is contested for its classist and sexist bias, it is also reconceptualised as a powerful tool to counterbalance - market-oriented instrumentalist uses of education. Seeking to contribute to these debates from the perspective of the history of education, my project will put into play a critical reading of Bildung in order to explore personal correspondence as - educational instruments in the life of English feminist, artist and philanthropist Barbara Bodichon (1827-1891). Persuaded of its potential as a thinking tool, reading letters through the lens of Bildung is an original way of exploring epistles as - sources of informal education for literate women in nineteenth-century England and an alternative path to review and nuance our understanding of this already studied historical figure. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - BBEB - - - H2020-MSCA-IF-2016 - - - 746054 - - - - - STOCKHOLMS UNIVERSITET - - - EUR 185 857,20 - - - Expanding Rights in an Age of Retrenchment: Women, Social Movements and the Politics of Family Leave - - - EUR 185 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - Recent innovations in family policy extend parental leave benefits to fathers and establish paid family leave to care for non-child relatives, such as spouses and parents. Such policies seek to ease work-life tensions, yet - there are considerable cross-country differences in the existence, duration and generosity of paid parental and family leave benefits. While welfare state theories offer several explanations for cross-country differences in family policies, we have - few explanations for policy content – who is included and excluded from provisions – and the timing of policy change. - - 2019-09-03, ongoing project - - - 2017-09-04 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - ERA - - - H2020-MSCA-IF-2016 - - - 742339 - - - - - SWANSEA UNIVERSITY - - - EUR 195 454,80 - - - Electrochemical Graphene Sensors as Early Alert Tools for Algal Toxin Detection in Water - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Episodes of harmful blue algae blooms and the associated algal toxin microcystin-LR (MC-LR) occur frequently in bodies of water worldwide as consequences of eutrophication resulting from anthropogenic activities such as - agricultural run-off, urban waste, and manufacturing of detergents and global warming. It had been confirmed that microcystins were responsible for some poisonings of animals and humans where water sources contained toxic cyanobacteria blooms. - Microcystins were potent and specific in inhibiting protein phosphatases 1 and 2A (PPl, PP2A). Acute or prolonged exposure to microcystins would cause liver damage, followed by a massive intrahepatic hemorrhage and probably leading to death. In 1998, - the provisional guideline concentration limit of 1 μg/L MC-LR in drinking water was assigned by the World Health Organization (WHO). The development of reliable methods for monitoring MC-LR in water resources is of great interest to determine the - occurrence and to prevent exposure to the toxin. Several methods have been developed to detect MC-LR, such as high-performance liquid chromatography/mass spectrometry (HPLC/MS) , bio-, biochemical- and immune-assays, which require long processing - times, sophisticated instruments, complex procedures, or high processing cost and are in general used in the laboratory, not in situ. A sensitive, specific, simple, and rapid method for monitoring MC-LR could help to prevent exposure to the toxin. - The unique physical and electrochemical properties (e.g., high electrical conductivity, ease of functionalization, high electrochemically active surface area, and broad range of working potentials in aqueous solutions) of graphene make them a - candidate material for developing novel and fit-for-purpose electrochemical biosensors/immunosensors as alternatives to the time-consuming, expensive, non-portable and often skills-demanding conventional methods of analysis involved in water quality - assessment. - - 2019-09-25, ongoing project - - - 2017-09-26 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - GrapheneBiosensor - - - H2020-MSCA-IF-2016 - - - 743993 - - - - - TECHNISCHE UNIVERSITEIT DELFT - - - EUR 177 598,80 - - - Uncovering viral sabotage of host CRISPR-Cas immune systems - - - EUR 177 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - CRISPR-Cas immune system represents one of the most effective weapons against mobile genetic elements in the host defense arsenal. Bacteriophages (phages) armed with anti-CRISPR proteins can, however, inhibit CRISPR immunity - by sabotaging components of the immune system with evolutionary advantages. This proposal sets out to discover novel phage-encoded anti-CRISPR proteins and understand the molecular mechanisms of the inhibitory processes. - - 2020-01-14, ongoing project - - - 2018-01-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - Anti-CRISPR - - - H2020-MSCA-IF-2016 - - - 753528 - - - - - THE UNIVERSITY OF SHEFFIELD - - - EUR 183 454,80 - - - Mobility and management of cattle in Iron Age and Roman Netherlands - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - This research project aims to study long-term developments in cattle management and mobility in the Netherlands, from the Iron Age to the Roman period (750 BC – AD 450). Cattle have always played a crucial role in this region, - in supporting arable farming by traction and manure, in providing food in the form of meat and dairy products, and in providing raw materials for clothing and artefacts. Our understanding of cattle management could be improved enormously by an - integrated study of traditional and newer methods of research. - - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - MoMa - - - H2020-MSCA-IF-2016 - - - 740394 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 183 454,80 - - - Towards a molecular understanding of the centriole assembly process - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The centriole is a conserved organelle essential for cell organisation, division and motility through its capacity to organise microtubules. A broad range of human diseases, such as microcephaly and cancer, have been - associated with defects in centriole formation, making the full characterisation of its assembly process of great interest. Centrioles are miniature cylinders of characteristic symmetry, diameter and length, yet the molecular methods by which these - parameters are defined are only partly understood. The objective of this proposal is to study the structure – function relationship of the centriolar proteins SAS-6, Cep135 and CPAP, which together form a protein interaction network that supports - centriole elongation and connects the core centriole scaffold with its microtubule-based exterior. This project will be carried out through an integrated, multi-disciplinary approach combining structural biology, biophysics and functional assays in - human cell lines. We will investigate the effect of disease-causing mutations in the structure and function of the SAS-6 – Cep135 – CPAP network. This work will boost our understanding of the centriole formation process and how it is perturbed in - disease, and be a pioneering example of elucidating the molecular architecture of a cell organelle. - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SAS6-Cep135-CPAP - - - H2020-MSCA-IF-2016 - - - 752069 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 144 230 - - - Revitalizing the clinical potential of type I IFNs in fighting influenza A virus infections with AcTaferon. - - - EUR 144 230 - - - France - - - Research Organisations - - Based on their antiviral and antitumor effect, type I interferons (IFNs) were believed to be the miracle drug to tackle viruses and cancer. However, clinical IFN applications remained limited due to severe side effects - resulting from widespread cellular sensitivity to IFN, which limits the administrable doses. Hence, the drug concentration at the desired infection or tumor site is often too low to be fully therapeutic efficient. AcTaferon (Activated-by-Targeting - interferon), co-developed by Prof. Uzé, circumvents these obstacles. By fusing an IFN mutant with strongly reduced receptor binding affinity to a targeting moiety that recognizes a surface marker on specific cells, AcTaferon remains inactive “en - route” through the body and unveils its biological activity only on specific target cells. Robust tumor regression without side effects and preliminary antiviral effects underscore the huge clinical potential of AcTaferon to fight cancer and viral - diseases. By combining the AcTaferon and influenza expertise of Prof. Uzé and Prof. Saelens, respectively, this interdisciplinary project offers the opportunity to broaden the innovative AcTaferon therapeutic strategy from the cancer to the viral - infection field. Influenza A was selected as a pilot target as seasonal influenza A epidemics and occasional pandemics remain a serious health threat causing substantial morbidity and mortality. Influenza A-targeted AcTaferons will be developed and - analyzed in relevant in vitro and in vivo models. Eventually, all knowledge will be transferred to Orionis, a company that will implement the AcTaferon technology to develop novel drugs. My background on the intracellular processes that negatively - regulate cytokine receptors and hence influence the cellular sensitivity to a (therapeutic) cytokine is an asset to this project. I will be able to extend my fundamental research experience with applied cytokine research, which may extend into a new - academic or industrial research pipeline. - - 2018-12-31, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - AcTaferon - - - H2020-MSCA-IF-2016 - - - 753112 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 185 076 - - - The molecular mechanism of E. coli FimH pathogenicity - - - EUR 185 076 - - - France - - - Research Organisations - - Pathogenic bacteria such as E. coli are responsible for a large variety of diseases, including persistent urinary tract and intestinal infections. Their adhesion to the host cell wall is promoted by the binding of FimH located - at the tip of the bacterial fimbriae to highly mannosylated cell surface receptors. To resist human defences such as the urinary flow, bacterial adhesion is enhanced under shear force. The shear-force dependence and thus also the pathogenicity of - different E. coli strains has been shown to depend on natural sequential variation of the FimH protein. Also probiotic E. coli strains have been shown to attach to host cells, which raises the question as to why these bacteria evoke a beneficial - effect upon their host. - - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - FimH-Mech - - - H2020-MSCA-IF-2016 - - - 750280 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 183 454,80 - - - Microrheology of two-dimensional active colloidal crystals and glasses - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Self-propelling colloidal particles, originally designed to mimic living microorganims, offer exciting opportunities to engineer smart materials equipped with activity. To date, the behavior of synthetic microswimmers has been - extensively studied in homogeneous environments, close to confinements and in semi-dilute suspensions. However, for materials’ design, the use of solid-like phases, such as crystals and glasses, is highly desirable. While recent numerical simulations - have invested a lot of effort in understanding the structural and mechanical properties of dense colloidal materials with activity, experiments significantly lag behind. One difficulty stems, for instance, from the presence of short-range attractive - forces that affect the active motion when two of more microswimmers come near contact. - - - 2019-09-03, ongoing project - - - 2017-09-04 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - MicACol - - - H2020-MSCA-IF-2016 - - - 747029 - - - - - THE QUEEN'S UNIVERSITY OF BELFAST - - - EUR 183 454,80 - - - Water and Baptism in Old English Poetry - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The purpose of this project is to offer the first comprehensive study of the function of water and its relationship with baptism in the four most significant Old English poetry manuscripts: the Exeter Book, the Vercelli Book, - the Junius XI and the Cotton Vitellius A XV. - - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - Cleansing Water - - - H2020-MSCA-IF-2016 - - - 744615 - - - - - UNIVERSITA DEGLI STUDI DI PADOVA - - - EUR 164 203,80 - - - Novel strategies for anti-HIV-1 therapy: Small molecules targeting RNA partners of the nucleocapsid protein - - - EUR 164 203,80 - - - Italy - - - Higher or Secondary Education Establishments - - European Commission considers HIV/AIDS as a top priority and significantly invests in research devoted to the development of alternative therapeutic strategies leading to new antiretrovirals, which are urgently needed to - overcome the emergence of resistance to existing drugs. - - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Italy - - - BICEPSvsHIV - - - H2020-MSCA-IF-2016 - - - 751931 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 195 454,80 - - - Algebraic Group Actions in Geometry, Arithmetic, and Physics - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - "Geometry, arithmetic, and quantum physics historically have had many points of intersection. This project will use recent techniques in algebraic group actions, especially those of Kirwan, to address problems of overlapping - interest to distinct research groups at the University of Oxford – Algebraic Geometry, Number Theory, Mathematical Physics, and the Centre for Quantum Mathematics and Computation. - - - 2019-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - AGAGAP - - - H2020-MSCA-IF-2016 - - - 742052 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 183 454,80 - - - Operando FTIR spectro-electrochemistry of hydrogenases: unraveling the basis of biological H2 production for innovative clean energy technologies - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Ongoing search for renewable energy technologies is essential in Europe to tackle the continuous increase in demand and the environmental and ethical concerns. Hydrogen is a promising renewable fuel, but so far its production - is not clean as the conventional industrial techniques start from fossil fuels. Production of H2 by biological, biotechnological or bioinspired methods would solve this problem and the study of FeFe-hydrogenases is a key step in this process. For - this reason, the proposal is well aligned with the EU Societal Challenges in “Secure, clean and efficient energy”. FeFe-hydrogenases are efficient metalloenzymes that catalyse H2 production from water at high turnover rates, using Fe, rather than Pt - active sites. Building on my previous experience with these enzymes, in this project I will apply a highly innovative approach to investigate how nature uses cheap iron to catalyse H2 production. Protein film infrared (IR) electrochemistry was - recently developed by Prof Vincent at the University of Oxford, allowing electrochemical triggering of enzyme catalysis with simultaneous IR spectroscopic study of how the enzyme works. This will provide a deep understanding of enzyme - structure/function relationships, from coordinated electron and proton transfer to structural rearrangements at the Fe site. Due to my prior expertise in FeFe hydrogenases which are not studied in the host group, and Oxford’s excellence in - bio-spectroscopy, the Fellowship will promote exceptional bidirectional knowledge transfer. Dissemination of research through Oxford’s outreach programs will increase the impact of the project to varied audiences. Access to the well-established - training and career development activities in Oxford, and the world-class programs of visiting speakers, will advance my career as I gain new knowledge and skills, enhance my scientific profile by acquiring international experience, expand my - scientific horizon, strengthen my skills, and build new networks. - - 2020-02-29, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - H2Bio2Energy - - - H2020-MSCA-IF-2016 - - - 752305 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 195 454,80 - - - Energy-generating synthetic tissues - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Synthetic tissues are of great scientific and technological importance as they might not only enable purpose-driven complementation of natural tissue functionalities to repair or replace dysfunctional or damaged tissues, but - also allow the engineering of intelligent artificial biomaterials with features that do not exist in nature. Main limitations of current synthetic tissues based on lipid-coated droplet networks are a low material durability over the long-term, a low - availability of diverse functions (apart from electrical communication and macroscopic deformation) and a lack of control capacity using external signals in a reversible manner. The main goal of this proposed project is the engineering of a novel - light-controllable synthetic tissue capable of generating energy, which consists of a printed network of polymer-coated droplets that carry specific enzymes within distinct droplets. Such energy-generating synthetic tissues convert chemical energy - into electrical energy, and might therefore be applied as miniature bio-batteries to power implanted medical devices such as pacemaker in human patients. Engineering of synthetic cells and bio-batteries are a current focus of the 2017 Work Programme - of European Commission and will advance the development of industrial biotechnology, which is one of Key Enabling Technologies of European industrial policy. - - 2020-04-30, Grant Agreement signed - - - 2018-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - United Kingdom - - - ENERGSYNTISSUE - - - H2020-MSCA-IF-2016 - - - 750801 - - - - - UNIVERSITA DEGLI STUDI DI PADOVA - - - EUR 180 277,20 - - - Combining Remote Sensing Technologies for Peatland Detection and Characterization - - - EUR 180 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - CReScenDo aims at quantifying the extent and thickness of peatlands from the local to the regional scale, to accurately define their importance in the global carbon cycle. Peatlands are extraordinary reservoirs of organic - carbon (almost matching, according to some estimates, the atmospheric carbon pool), which is currently being released into the atmosphere due to a number of often anthropogenic degradation processes (e.g. soil drainage, fires, etc.). The conservation - of peatlands is therefore a key measure to reduce CO2 emissions and to mitigate climate change (e.g. according to the Intergovernmental Panel on Climate Change). However, regional and global estimates of peat deposits remain highly uncertain and an - effective quantification methodology is still missing, negatively impacting our ability to plan effective conservation strategies. The innovative approach proposed by CReScenDo combines passive and active satellite remote sensing and geophysical data - collected from airborne platforms to map extent and thickness of peat deposits at regional scale. The proposed methodology will yield a set of integrated observations providing the first large-scale picture of the relations among peat deposits, - geomorphological features, and soil and environmental characteristics. Three peatland areas (two in Europe and one in Asia) are selected to implement and test the methodology, using field observations to improve the accuracy and quantify the - uncertainty. The ability of the methodology to characterize/classify different peat types will also be tested and used to map the carbon pool stored at the three study sites. The applicant has a solid background in optical remote sensing and - ecological modelling applied to salt-water wetlands. The hands-on training performed at the host institution and at a private company (Secondment) will provide her with new scientific competences in topographic and geophysical data analysis tools - with tremendous impact on her mid/long-term career. - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Italy - - - CReScenDo - - - H2020-MSCA-IF-2016 - - - 747809 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 183 454,80 - - - Quantum Systems Investigated through Tensor Network States - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Tensor Network States (TNS) are a class of variational wave functions whose number of parameters can be increased systematically in order to improve the accuracy of the approximation. In effectively one dimensional systems, - such as certain magnetic insulators, TNS reproduce the macroscopic properties of the ground state by 1 part in 10 million. TNS are expected to eventually give rise to similar accuracies in higher dimensions, though, in this case, their numerical - implementation is much more sophisticated. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - quasiTENS - - - H2020-MSCA-IF-2016 - - - 749150 - - - - - JOHN INNES CENTRE - - - EUR 195 454,80 - - - How do pathogens exploit the symplast to promote disease? - - - EUR 195 454,80 - - - United Kingdom - - - Research Organisations - - It is well established that pathogens invade plant cells to establish an infection. Part of a biotrophic pathogen’s infection strategy is to secrete effectors into host cells in order to manipulate host processes to the - pathogen’s benefit. It has been observed that some effectors can move from cell-to-cell in the host and this suggests that a pathogen can invade and exploit cells surrounding the immediate infection site. To further support this hypothesis, my host - lab observed that PAMP-induced plasmodesmata (PD) closure is suppressed in some virulent infections, suggesting pathogens attempt to keep intercellular connections open; some pathogens must maintain intercellular symplastic connectivity by - counteracting PAMP-induced PD closure to promote disease. This proposes the question: why does a pathogen want PD open? We hypothesise that open PD allow pathogen effectors to move into non-infected cells where they targeting host processes to - promote infection and allow pathogen access host resources such as sugars. In this study, I will use the Hyaloperonospora arabidopsidis– Arabidopsis interaction to identify cell-to-cell mobile effectors and their host targets. I will identify global - changes of host gene regulation that are associated with cell-to-cell mobile effectors and examine the effect of cell-to-cell mobile effectors on sucrose transport around an infection site. The results will give insight into how pathogens exploit the - symplast and non-infected cells to promote infection, characterising a poorly considered element of plant-pathogen interactions. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - HOPESEE - - - H2020-MSCA-IF-2016 - - - 749755 - - - - - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH - - - EUR 187 419,60 - - - Closing in on New Physics in light-quark flavour transitions: from tau decays to the LHC - - - EUR 187 419,60 - - - Switzerland - - - Research Organisations - - This action studies the synergy of the Energy and the Intensity Frontiers, with the focus on non-standard effects involving leptons and light quarks. The project starts with an unprecedented Effective-Field-Theory (EFT) - analysis of hadronic tau decays including non-standard effects. Their discovery potential and complementarity with direct LHC searches will be assessed in a model-independent approach. The results will be combined with d(s)→u l nu (l=e,mu) - transitions and eq → eq (q=u,d,s) processes in a comprehensive EFT flavour fit that will close in on New Physics involving leptons and light quarks. - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - Tau-SYNERGIES - - - H2020-MSCA-IF-2016 - - - 745954 - - - - - POLITECNICO DI TORINO - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - UNIVERSITAET STUTTGART - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - ECOLE CENTRALE DE LYON - MIDDLE EAST TECHNICAL UNIVERSITY - TECHNISCHE UNIVERSITAET MUENCHEN - BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION - VYSOKA SKOLA BANSKA - TECHNICKA UNIVERZITA OSTRAVA - CRAY UK LIMITED - MAVEL AS - - - EUR 3 815 947,44 - - - models, EXperiments and high PERformance computing for Turbine mechanical Integrity and Structural dynamics in Europe - - - EUR 3 815 947,44 - - - Italy - United Kingdom - Germany - United Kingdom - France - Turkey - Germany - Spain - Czech Republic - United Kingdom - Czech Republic - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Energy and Mobility are two primary driving forces in the 21st century. Development of incremental and disruptive technologies will have key impacts on the world’s societies, and on safety, security and competitiveness of - Europe. Amongst those technologies, gas turbines will play a major role. Recovery of shale gas depends decisively on compressors. Modern gas supplied power plants are bridging towards the age of renewable energies. Aeroengines are to undergo the most - massive changes in their history with the advent of composite materials, gear boxes, and turbine-electric concepts separating generation of power and thrust. A technological commonalities of the upcoming challenges is the need for full model based - development and computer system simulation. - - 2021-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Italy - - - EXPERTISE - - - H2020-MSCA-ITN-2016 - - - 721865 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 183 454,80 - - - Engineering Electron-Phonon Interactions of Two-Dimensional Materials from First-Principles - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Two-dimensional (2D) materials such as graphene and transition metal dichalcogenide monolayers receive a tremendous amount of attention because of their extraordinary properties and application potential. Electron-phonon - interactions, which couple the electronic and lattice vibrational degrees of freedom in solids, affect a wide range of material properties, for example lattice stability and carrier mobility. Importantly, the strength of electron-phonon interactions - in 2D materials can be tuned to a significant extent by electric field doping and elastic deformation, opening up the possibility of rational engineering of electron-phonon interactions in 2D materials. - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - EPIC2D - - - H2020-MSCA-IF-2016 - - - 743580 - - - - - DANMARKS TEKNISKE UNIVERSITET - - - EUR 212 194,80 - - - PRobabilistic PRedictIon for Smart Mobility under stress scenarios - - - EUR 212 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - PRISM is about designing, implementing and testing methodologies to better predict transport demand in a city. While plenty solutions exist today for this objective, there is general consensus that, under stress scenarios - (e.g. large social events, inclement weather, demonstrations, special days), those approaches are insufficient. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Denmark - - - PRISM - - - H2020-MSCA-IF-2016 - - - 745673 - - - - - KING'S COLLEGE LONDON - - - EUR 195 454,80 - - - Greek Identity in Art Music since the Early Nineteenth Century: Towards an Interdisciplinary Methodology - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - This project is the first large-scale, interdisciplinary attempt to study mechanisms of national identity construction through modern Greek (post-1830) art music. It has two primary objectives: a) to develop an - interdisciplinary methodological framework for the analysis of Greek art music drawing on historical musicology, Modern Greek Studies and ethnomusicology; and b) to offer a revisionist study of Greek art music – a repertory that remains to be - investigated in the depth it merits – by exploring the ways in which it has mediated Greek identity during the period since the formation of the Greek nation-state in the early 19th century. Traditionally, the issue of “Greekness” – a perceived - national character or identity – in music has been analysed with respect to the question of the assumed “continuity” of Greek history and culture since antiquity, as well as a quest for authenticity, purity, loyalty and uniqueness. Yet, such - treatment of national identity is essentialising and self-exoticising. Recent scholarship on Greek music is starting to recognise the usefulness of contemporary methods of historical and cultural contextualisation. These approaches have much to gain - from dialogue with a) recent critical discourses developed to understand and contextualise the concept of “Greekness” within modern Greek studies and b) ethnomusicological approaches to the study of music and identity. This project will equip me to - become the first specialist on Greek art music to use an interdisciplinary methodology for the analysis of this music that draws on historical musicology, modern Greek studies and ethnomusicology, a method that has the potential to become - paradigmatic for the study of other national repertories too and useful for other disciplines. The research will exploit archival sources while also drawing upon ethnographical methods. The outcomes will be: 1) a monograph, 2) two conference papers, - 3) a series of public lectures and 4) a seminar series. - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - GRIDAMUS - - - H2020-MSCA-IF-2016 - - - 745631 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 183 454,80 - - - Detection of biocontrol agents from casing material to inhibit mushroom mycoparasites through casing microbiome characterization and Raman spectroscopy of isotopically labelled organisms. - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Mycoparasites cause significant crop losses in the cultivated mushroom Agaricus bisporus, but as fungal pathogens of cultivated fungi pose major challenges for disease control. The casing layer used to cover mushroom compost - supports a diverse community of microorganisms with potential to act as host-specific biocontrol agents capable of inhibiting the germination or growth of mycoparasitic fungi, while even promoting mushroom development. In this project we propose to - apply novel and state-of-the-art techniques to characterize the casing microbiome along the crop cycle and identify potential biocontrol agents to control bubble diseases by amending casing with a stable synthetic microbial ecosystem. High-throughput - community analysis, developed by the host group and used for the characterization of the plant microbiome, will be implemented to analyse the complete community structure of a suppressive casing material. Target materials will be selected through - pilot trials conducted within the Partner Organization (PO) facilities. Potential antagonistic bacteria will be valuated to detect and isolate biocontrol agents through isotopic labeling of fungi (a new protocol for labeling spores and hyphae will be - developed) and Raman-confocal microspectroscopy. Potential biocontrol agents will be finally tested in a pilot trial. The project builds a consortium formed by two European institutions, including certain departments from the academic host - institution (University of Oxford, UK) and one non-academic PO (ASOCHAMP RIOJA, Spain), a research centre with extensive experience analysing casing materials and mycoparasites. It has been designed to augment and complement the research and - transferable skills sets of the Marie Curie fellow and will greatly enhance his career prospects accordingly. Through the training and the research results arising, the Fellowship will be beneficial to the fellow, the host institution, the PO, the - mushroom industry and the European society. - - 2019-03-12, ongoing project - - - 2017-03-13 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - MYCOBIOME - - - H2020-MSCA-IF-2016 - - - 742966 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 223 152,92 - - - The Curiosity Carnival: Oxford European Researchers’ Night 2017 - - - EUR 407 172 - - - United Kingdom - - - Higher or Secondary Education Establishments - - By capitalising on the University of Oxford’s world-class European-funded research base, together with our outstanding museums, libraries, gardens and woods, education programmes and public engagement expertise, we will create - a truly inspirational multi-venue multi-disciplinary European Research night in 2017 on the theme of ‘People and Planet'. - - 2017-12-31, closed project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.5."> - - - MSCA-NIGHT-2016 - European Researchers' Night - - - CSA - Coordination and support action - - - United Kingdom - - - Curiosity Carnival - - - H2020-MSCA-NIGHT-2016 - - - 722615 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - JANSSEN CILAG SA - - - EUR 1 341 024,48 - - - Late Stage Fluorination and its Applications to Drug Discovery - - - EUR 1 341 024,48 - - - United Kingdom - Spain - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - All of modern medicine is dependent on advances in chemistry and the healthcare goalposts have moved as the century has progressed. The pressing need to shorten cycle times and reduce the costs of drug discovery has led pharma - and the clinicians that guide them to use scanning techniques such as positron emission tomography (PET), enabling them to increase disease understanding, study target engagement with therapeutics and improve decision making, so that only the best - candidate molecules progress to the later stages of drug development. Overcoming these challenges requires multidisciplinary knowledge, and can be facilitated through stronger links between academia and Pharma. Chemical entities substituted with - fluorine or fluorine-containing groups are frequently used to design drugs with improved pharmacological and pharmacokinetic profiles that provide important benefits over existing therapies, such as superior safety, efficacy, dosing, and patient - compliance. Furthermore, 18F is often selected as the preferred positron-emitting isotope for the labeling of PET tracers due to its advantageous properties. The scientific objective of FLUDD is to develop novel late stage fluorination chemistry to - populate the chemical and radiochemical space available for drug discovery with a focus on novel fluorine-containing fragments, molecules and biomolecules that are not directly accessible from commercial sources or the scientific literature. These - novel methodologies will be applied to drugs and diagnostics discovery using both small molecules and proteins. The educational objective is to train the next generation of doctoral scientists in the practice of chemical synthesis and radiochemical - methods with an in-depth appreciation of their applications in medicine. FLUDD objectives will be met with a novel Oxford-Janssen Alliance augmented with leading partners from academia, industry and the clinic. - - 2021-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-EID - European Industrial Doctorates - - - United Kingdom - - - FLUDD - - - H2020-MSCA-ITN-2016 - - - 721902 - - - - - FUNDACIO PRIVADA INSTITUT CATALA D'INVESTIGACIO QUIMICA - FUNDACIO PRIVADA INSTITUT CATALA D'INVESTIGACIO QUIMICA - - - EUR 149 750 - - - Late-stage catalytic carboxylation techniques with labelled carbon dioxide: new opportunities for radiolabelling - - - EUR 149 750 - - - Spain - Spain - - - Research Organisations - Research Organisations - - Absorption, distribution, metabolism and excretion´s studies (ADME) are essential for drug discovery and development, providing invaluable preclinical data to understand how the drug behaves in living organisms, thus allowing - to make a decision on whether the drug should be terminated or advanced to the next step. At present, most of these studies are performed with a radiolabelled 14C-labelled version of the drug; unfortunately, current radiolabelling syntheses rely on - lengthy-step sequences or rather expensive 14C-labelled building blocks, dramatically raising the costs for the research and development, and delaying the execution of preclinical studies. Taking into consideration that carboxylic acids are - privileged motifs in a myriad of agrochemicals or pharmaceuticals, LABEL-DIOX offers the opportunity of promoting a late-stage carboxylation event with labeled CO2. The protocol is user-friendly, with components that are neither air- nor moisture - sensitive, utilizes earth-abundant catalysts and operates under mild conditions. LABEL-DIOX will increase the overall efficiency of the carbon isotope incorporation, reduce the costs that would have resulted from the design of a lengthy radiolabelled - synthesis, minimize the costs for waste disposal and dramatically increase the revenues, thus changing the way industrial chemists conduct radiolabelling of drugs containing carboxylic acids. - - 2019-05-31, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Spain - - - LABEL-DIOX - - - ERC-2016-PoC - - - 755251 - - - - - TECHNISCHE UNIVERSITEIT EINDHOVEN - CHALMERS TEKNISKA HOEGSKOLA AB - AALTO-KORKEAKOULUSAATIO - KATHOLIEKE UNIVERSITEIT LEUVEN - THE UNIVERSITY OF LIVERPOOL - LEVEL ACOUSTICS BV - MATELYS - RESEARCH LAB - MATERIALISE NV - SIEMENS INDUSTRY SOFTWARE NV - MOELVEN TOREBODA AB - - - EUR 3 907 082,88 - - - A sound fundament for our future buildings - - - EUR 3 907 082,88 - - - Netherlands - Sweden - Finland - Belgium - United Kingdom - Netherlands - France - Belgium - Belgium - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - To ensure a healthy environment for people living and working in buildings, research and engineering in the area of building acoustics is essential. Developments in modern building concepts, such as sustainable low-energy - consuming buildings, buildings with lightweight materials and open plan working environments, as well as the need to build in extremely noisy areas, require involvement of acoustic experts in order to successfully (re)design buildings without - negatively impacting upon people’s health and well-being. Taking up current and future acoustic challenges requires innovative solutions based on a thorough understanding and mastering of modern methods and tools, as well as a holistic acoustic - approach involving acoustic design, products and subjective evaluation. However, in the complex field of building acoustics, research activities typically are not holistic and have become slightly marginalised. As a consequence, there is a lack of - building acoustics experts. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Netherlands - - - Acoutect - - - H2020-MSCA-ITN-2016 - - - 721536 - - - - - TECHNISCHE UNIVERSITEIT DELFT - TECHNISCHE UNIVERSITEIT DELFT - - - EUR 1 998 985 - - - Signal Transduction in Organic Materials - - - EUR 1 998 985 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - It is the overall aim of this project to use responsive catalysts to introduce signal transduction cascades in soft materials, enabling autonomous, programmable and amplified response of soft materials to chemical signals from - their environment. 'Smart' soft materials could find many important applications ranging from personalized therapeutics to soft robotics. However, as most molecular materials are unable to communicate, or even respond to, changes in their - environment, truly smart materials are still far out of reach. Signal transduction is one of the primary processes used by living cells to react to events taking place in their environment, often involving a signal triggering enzymatic activity, - leading to a cellular response. Such rudimentary communication is entirely non-existent in synthetic materials. I here propose the introduction of catalysis-based signal transduction between chemical systems to enable synthetic materials to respond - autonomously to events taking place in their environment. Key to achieving this objective will be the development of switchable catalysts, using signals originating from chemical events to change catalytic activity, and coupling changes in catalytic - activity to responses in soft materials. In achieving these objectives, I will develop new design strategies for responsive soft materials, enabling control over material formation and response in time and space, through autonomous reaction to - chemical signals. This will allow the development of new actuators, self-healing materials, sensors, therapeutics and self-regulation and self-correction of material assembly. It will also constitute an entirely new role for catalysis, as catalysis - will be engaged to constitute a first step towards achieving communication between artificial chemical systems. - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - STORM - - - ERC-2016-COG - - - 726381 - - - - - RIJKSUNIVERSITEIT GRONINGEN - RIJKSUNIVERSITEIT GRONINGEN - - - EUR 1 999 970 - - - Design and Engineering Next-Generation Nanopore Devices for Bioplymer Analysis - - - EUR 1 999 970 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Nanopores have emerged in the past few years as a promising analytical technique. The basic concept of nanopore sensing is to apply a potential across individual nanoscale pores and observe the disruption of the ionic flow - caused by single molecules entering the pore. Ionic currents through protein pores have been successful at recognizing tiny differences in molecules in solution. Most notably, arrays of thousands of nanopores integrated in low-cost and portable - devices are now capable of sequencing DNA at the single-molecule level. The main challenge of nanopore sensing is the inability of controlling the protein pore diameter and geometry, which determines the signal and enables selectivity based on - physical size. - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - DeE-Nano - - - ERC-2016-COG - - - 726151 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 195 454,80 - - - The Digest and the Exploitation of the Countryside in the Western Roman Empire (2d cent. BC-3rd cent. AD).Evidence of the water control - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Every aspect of the ancient world depended on the control and exploitation of the countryside, but scholars have until recently failed to engage with an abundant and detailed material on the subject: the legal texts of the - Digest. The thought of the Roman jurists constituted a powerful model for all the minor and local institutions and legal documentation reveals not only rules, but also actual practices and issues of unquestionable historical interest. Amongst the - significant amount of legal texts concerning the countryside, the issues of water sharing and that of erosion and flood risks management are particularly well represented, constituting a key element of an essential aspect of the ancient economy, i.e. - the agricultural production. However, an overall underestimation has led to a serious insufficiency of methodology concerning these texts, an evident obstacle to its exploitation in a historical perspective. This research proposes to demonstrate how - relevant the study of Roman law is for our knowledge of the Roman countryside, by confronting the strikingly unexplored jurisprudential documentation with more traditionally exploited archaeological and environmental sources. The focus on water - control is motivated by a will to concentrate on a crucial condition of the exploitation of the countryside, which has raised sufficient interest from the ancient jurists themselves, as well as from the scholars in the past decades, so as to generate - enough primary and secondary sources for us to consider. The objective is twofold: first, to establish a clear and consistent methodology for the historical study of the jurisprudential sources; second, to apply it to case studies in order to produce - new insights into a fundamental issue of the Roman world. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - DEXCORE - - - H2020-MSCA-IF-2016 - - - 742523 - - - - - INSTITUTE OF EXPERIMENTAL MEDICINE - HUNGARIAN ACADEMY OF SCIENCES - INSTITUTE OF EXPERIMENTAL MEDICINE - HUNGARIAN ACADEMY OF SCIENCES - - - EUR 2 000 000 - - - Microglial control of neuronal activity in the healthy and the injured brain - - - EUR 2 000 000 - - - Hungary - Hungary - - - Research Organisations - Research Organisations - - Microglia are the main immune cells of the brain, but their role in brain injury is highly controversial due to the difficulties in selectively manipulating and imaging microglial actions in real time. Specifically, it is - unclear whether microglia control neuronal survival after injury via shaping the activity of complex neuronal networks in vivo. To this end, we have combined fast in vivo two-photon imaging of neuronal calcium responses with selective microglial - manipulation for the first time. Our data suggest that microglia constantly monitor and control neuronal network activity and these actions are essential to limit excitotoxicity and neuronal death after acute brain injury. We also identify microglia - as key regulators of spreading depolarization in vivo. However, the underlying mechanisms remained unexplored. Here, I propose that microglia control neuronal excitability and based on preliminary data I set out to investigate how this occurs. We - will combine selective, CSF1R-mediated microglia depletion with advanced neurophysiological methods such as in vivo calcium imaging and intracranial EEG for the first time, to reveal how microglia shape activity of complex neuronal networks in the - healthy and the injured brain. Then, we will study microglia-neuron interactions from the network level to nanoscale level using in vivo two-photon imaging and super-resolution microscopy. We will apply novel chemogenic and optogenetic approaches to - manipulate microglia in real time, assess their role in neuronal activity changes and investigate the molecular mechanisms in vitro and in vivo. Our unpublished data also suggest that inflammation – a key contributor to brain diseases – could disrupt - microglia-neuron signaling and we set out to investigate the underlying mechanisms. By using state-of the-art research tools that had not been applied previously in this context, our studies are likely to reveal novel pathophysiological mechanisms - relevant for common brain diseases. - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Hungary - - - MicroCONtACT - - - ERC-2016-COG - - - 724994 - - - - - UNIVERSITY OF SOUTHAMPTON - UNIVERSITY OF SOUTHAMPTON - UNIVERSITAET ROSTOCK - - - EUR 1 455 590 - - - Bayesian Agent-based Population Studies: Transforming Simulation Models of Human Migration - - - EUR 1 455 590 - - - United Kingdom - United Kingdom - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The aim of BAPS is to develop a ground-breaking simulation model of international migration, based on a population of intelligent, cognitive agents, their social networks and institutions, all interacting with one another. The - project will transform the study of migration – one of the most uncertain population processes and a top-priority EU policy area – by offering a step change in the way it can be understood, predicted and managed. In this way, BAPS will effectively - integrate behavioural and social theory with modelling. - - 2021-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - BAPS - - - ERC-2016-COG - - - 725232 - - - - - FUNDACIO INSTITUT DE CIENCIES FOTONIQUES - FUNDACIO INSTITUT DE CIENCIES FOTONIQUES - - - EUR 2 748 437 - - - Topological nano-photonics - - - EUR 2 748 437 - - - Spain - Spain - - - Research Organisations - Research Organisations - - One of the most fascinating phenomena in nature is the interplay between quantum mechanics and the flow of electrons in solids. A tangible example is the quantum hall effect, where electrons flow with virtually zero - dissipation. That is because electrons can flow only in one direction, which makes them move around objects without scattering, representing robustness by topological protection. Essential for this effect is the magnetic field that breaks - time-reversal symmetry. - - 2022-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Spain - - - TOPONANOP - - - ERC-2016-COG - - - 726001 - - - - - UNIVERSIDAD COMPLUTENSE DE MADRID - UNIVERSIDAD COMPLUTENSE DE MADRID - - - EUR 150 000 - - - Automated tools for atomic resolution mapping of electrostatic fields in the electron microscope - - - EUR 150 000 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The overarching goal of this proposal is to produce a software tool that will allow inexpensive atomic resolution mapping of electrostatic potentials and fields within materials in the electron microscope. Such mapping - capabilities could revolutionize our understanding of future materials for devices based on exploiting functionalities such as ferroelectric polarization. During the last decade, the scientific community has addressed this pressing need by developing - microscopy techniques sensitive to the local potential such as the recently reported differential phase contrast (DPC) imaging technique. DPC can, for the first time, map the distribution of electrostatic potential and field within a material in an - atomic column-by-atomic column fashion in a direct way. However, DPC imaging relies on the use of non-flexible segmented detectors with non-linear geometries. The increasing degree of physical complexity has made this approach rather unaffordable for - a conventional materials research lab composed of non-specialists. The technology we propose here will replace such detectors by software tools and produce similar atomic resolution maps. The key idea is to acquire electron diffraction images with - more conventional detectors and then apply post-acquisition analysis routines. Pixelated detectors (i.e., cameras) will be used to record the variation of the electron diffraction pattern as a function of probe position. Imaging configurations - similar to DPC will be chosen after acquisition: a given detector geometry can be reproduced off-line by partial, ad-hoc integration of regions of the electron diffraction pattern over at each probe position. Basic mathematical operations between - images ensuing form those different regions of the bright field disk will produce a DPC image in a straightforward manner. Such a technology will outsmart complex non-flexible hardware only by inexpensive software routines working on the new - generation of ultra-fast cameras. - - 2019-05-31, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Spain - - - POLAR-EM - - - ERC-2016-PoC - - - 754735 - - - - - ABERYSTWYTH UNIVERSITY - ABERYSTWYTH UNIVERSITY - - - EUR 1 428 165 - - - The Global as Artefact: Understanding the Patterns of Global Political History Through an Anthropology of Knowledge -- The Case of Agriculture in Four Global Systems from the Neolithic to the Present - - - EUR 1 428 165 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Knowledge is an anthropological constant that is indissociable from the birth and interactions of human societies, but is at best a secondary concern for scholars of international relations and globalization. Contemporary - global studies are thus unable to account for the co-constitution of knowledge and politics at a macro-scale, and remain especially blind to the historical patterns of epistemic development that operate at the level of the species as a whole and have - shaped its global political history in specific, path-dependent ways up to now. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - ARTEFACT - - - ERC-2016-COG - - - 724451 - - - - - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - - - EUR 1 975 829 - - - Massive Gravity and Cosmology - - - EUR 1 975 829 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The ambition of this research program is to challenge the nature of gravity, provide an alternative to dark energy, and pave the way towards a potential resolution of one the most tantalizing problems of physics today: The Old - Cosmological Constant Problem. - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - MassiveCosmo - - - ERC-2016-COG - - - 724659 - - - - - OSPEDALE SAN RAFFAELE SRL - OSPEDALE SAN RAFFAELE SRL - - - EUR 1 496 994 - - - Tracking and predicting neurodegeneration spreading across the brain connectome - - - EUR 1 496 994 - - - Italy - Italy - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Current knowledge of neurodegenerative diseases is limited by poor understanding of how they progress through the central nervous system (CNS). It has recently been hypothesized that clinical progression in these conditions - involves the systematic spreading of protein misfolding along neuronal pathways. Protein aggregates would trigger misfolding of adjacent homologue proteins in newly-affected regions, and this would propagate in a “prion-like” fashion across - anatomical connections. This proposal seeks to decipher the mechanisms of network-based neurodegeneration by understanding how the complex architecture of brain networks (the connectome) shapes the evolving pathology of neurodegenerative diseases, - and to develop tools for monitoring disease progression from presymptomatic to later stages of the disease. - - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Italy - - - NeuroTRACK - - - ERC-2016-STG - - - 714388 - - - - - FUNDACIO INSTITUT DE CIENCIES FOTONIQUES - FUNDACIO INSTITUT DE CIENCIES FOTONIQUES - - - EUR 1 829 288 - - - How to build a brain? Engineering molecular systems for mechanosensation and -protection in neurons - - - EUR 1 829 288 - - - Spain - Spain - - - Research Organisations - Research Organisations - - Mechanical forces are ubiquitous signals that provide critical and dynamic information about the environments around cells and organisms. Signals about touch, sound, and movements are transmitted to specialized - mechanoreceptors but also deform the neuronal cytoskeleton of the central nervous system, particularly when strong forces are involved. Although failures to sense and cope with stresses are linked to human diseases including peripheral neuropathies - and dementias, little is known about the connections between biomechanics and disease. A major reason for this gap is the technical challenge of detecting forces and deformations within a living cell or organism. Given the poor prognosis associated - with neurodegenerative diseases, spinal cord injury and neuropathies, there is a strong need to develop a better understanding of neuronal mechanics. - - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Spain - - - MechanoSystems - - - ERC-2016-STG - - - 715243 - - - - - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - - - EUR 1 997 680 - - - Single Molecule Nanoscale Sensors for Improved Therapies and Diagnostics - - - EUR 1 997 680 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - One of the most significant challenges facing the healthcare community is the accurate and selective detection and quantification of trace levels of analyte. This can have enormous impact with numerous application, especially - in the context of biosensing, where applications can range from early stage detection of disease to the identification of new markers amongst others. These challenges are compounded when the analysis of real samples or even complex mixtures are - required. To address this need, single molecule or near single molecule methods are currently being heavily pursued which allows for the discrimination of events with low copy numbers by removing the “clouding” associated with ensemble averaging. - Although strategies for detecting single molecules have existed for a number of years, efficient and cost-effective label-free methods without the need for chemical modification are lacking especially when considering smaller molecules directly in - unprocessed clinical samples. As part of this proposal, I intend to address this limitation by developing new strategies in single molecule nanoscale sensing which will be both highly sensitive and selective for improved therapeutics and diagnostics - applications. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - NanoPD - - - ERC-2016-COG - - - 724300 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 1 199 319 - - - Zooarchaeology and Mobility in the Western Mediterranean: husbandry production from the Late Bronze Age to Late Antiquity - - - EUR 1 199 319 - - - Spain - Spain - United Kingdom - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - - Human survival and success is substantially determined by the ability to move across the landscape and adapt. Consequently, ‘mobility’ is a crucial topic in historical and archaeological research. To overcome the seasonal - scarcity of food and the related over-grazing of pastures, it is essential for animal husbandry to move across territories. However, the decision to allow or deny rights of way to mobile people and livestock depends on political judgements. How might - these shape animal husbandry production, and society? - - 2021-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Spain - - - ZooMWest - - - ERC-2016-STG - - - 716298 - - - - - UNIVERSITAETSMEDIZIN GOETTINGEN - GEORG-AUGUST-UNIVERSITAET GOETTINGEN - STIFTUNG OEFFENTLICHEN RECHTS - UNIVERSITAETSMEDIZIN GOETTINGEN - GEORG-AUGUST-UNIVERSITAET GOETTINGEN - STIFTUNG OEFFENTLICHEN RECHTS - - - EUR 1 991 445 - - - Computational Dissection of Effective Circuitry and Encoding in the Retina for Normal and Restored Vision - - - EUR 1 991 445 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Understanding how neural circuits process and encode information is a fundamental goal in neuroscience. For the neural network of the retina, such knowledge is also of concrete importance for the development of vision - restoration therapies for patients suffering from degeneration of photoreceptors. Artificial stimulation of retinal neurons through electronic implants or inserted light-sensitive proteins (“optogenetics”) aims at reconstructing natural transmission - of visual information to the brain. Recreating natural retinal activity, however, will require a thorough understanding of the complex and diverse neural code of the retina. The challenge lies in deciphering the various nonlinear operations and - dynamics in the around 30 parallel signalling streams that emerge from the retina, represented by as many types of ganglion cells, the retina’s output neurons. - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - CODE4Vision - - - ERC-2016-COG - - - 724822 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 149 989 - - - Nano Impacts for Biomedical and Environmental Analysis - - - EUR 149 989 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - NIBEA will turn the developments and understanding from NANOIMPACTS into real world analytical practice such that reliable analytical protocols are established, validated and demonstrated especially in the context of real - world media (environmental, industrial, medical) providing an entirely new approach to nanoparticle analysis based on electrochemical measurements. - - - 2018-10-31, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - NIBEA - - - ERC-2016-PoC - - - 727292 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 1 696 109 - - - The Politics of Wealth Inequality and Mobility in the Twenty-First Century - - - EUR 1 696 109 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Over the past decade scholars across the social sciences have grappled with the causes and consequences of economic inequality and social mobility. Income inequality has risen to levels unseen for a century. At the same time, - economies in Europe and beyond have seen an even larger concentration in wealth, along with unprecedented volatility in asset markets such as housing and equities. These changes in the distribution of wealth have been of great economic and political - consequence, with the debates over housing, inheritance, and capital taxation shaping contemporary political discourse. Yet, scholars of political economy remain beholden to analyses of inequality and mobility that examine only the flows of income in - the labour market and ignore inequality and mobility in the stock of wealth held by citizens. WEALTHPOL is a ground-breaking interdisciplinary project with a series of three high-risk and novel work packages that transform our knowledge about wealth - inequality and wealth mobility. WEALTHPOL 1 develops the first comprehensive collection of data about the distribution and inheritance of wealth in Europe and beyond. WEALTHPOL 2 provides the first political database of how governments shape the - pattern of wealth through political pledges and policymaking, spanning seven decades and thirty-seven countries. Finally, WEALTHPOL 3 uses cutting-edge laboratory and survey experiments to expand our knowledge about what citizens think about wealth. - WEALTHPOL draws these three strands together by connecting policy environments and the distribution of wealth to citizens’ attitudes to wealth inequality and the kinds of policies that might shape it. In doing so, WEALTHPOL revolutionises our - understanding of - and our capacity to respond to - the politics of capital in the twenty-first century in Europe and beyond. - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - WEALTHPOL - - - ERC-2016-COG - - - 724949 - - - - - UNIVERSITE DU LUXEMBOURG - UNIVERSITE DU LUXEMBOURG - - - EUR 1 499 788 - - - Electoral Legacies of War: Political Competition in Postwar Southeast Europe - - - EUR 1 499 788 - - - Luxembourg - Luxembourg - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - We know remarkably little about the impact of war on political competition in postwar societies in spite of the fact that postwar elections have garnered tremendous interest from researchers in a variety of fields. That - interest, however, has been limited to establishing the relationship between electoral democratization and the incidence of conflict. Voters’ and parties’ electoral behaviour after the immediate post‐conflict period have remained largely neglected by - researchers. The proposed project will fill this gap in our understanding of electoral legacies of war by analysing the evolution of political competition over the course of more than two decades in the six postwar states of Southeast Europe: - Bosnia-Herzegovina, Croatia, Kosovo, Macedonia, Montenegro, and Serbia. Organised around three thematic areas/levels of analysis – voters, parties, communities – the project will lead to a series of important contributions. Through a combination of - public opinion research, oral histories, and the innovative method of matching of individual census entries, the project will answer to which extent postwar elections are decided by voters’ experiences and perceptions of the ended conflict, as - opposed to their considerations of the parties’ peacetime economic platforms and performance in office. In-depth study of party documents and platforms, party relations with the organisations of the postwar civil sector, as well as interviews with - party officials and activists will shed light on the influence of war on electoral strategies, policy preferences, and recruitment methods of postwar political parties. And a combination of large-N research on the level of the region’s municipalities - and a set of paired comparisons of several communities in the different postwar communities in the region will help expose the mechanisms through which war becomes embedded into postwar political competition and thus continues to exert its influence - even decades after the violence has ended. - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Luxembourg - - - ELWar - - - ERC-2016-STG - - - 714589 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 1 999 318 - - - Large-Area Transparent Opto-Electronics using 2D Materials - - - EUR 1 999 318 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Research in 2D materials has increased dramatically since the first isolation of graphene in 2004, with diverse interdisciplinary studies. In the last few years, 2D material research expanded beyond graphene by the development - of other 2D materials, such as monolayered transition metal dichalcogenides, black phosphorous, and Boron Nitride. There are hundreds of possible 2D crystals that can be isolated, with properties ranging from metallic, semi-metallic, semiconducting - to insulating, depending on the material composition. Semiconducting 2D materials have attracting interest in next-generation electronics/opto-electronics such as transistors, photo-gated transistors, photo-detectors, solar cells, and light emitting - devices (LEDs), molecular sensors and optical imaging sensors. The unique structural form of 2D materials provides several benefits over other existing materials: ultrathin, flexible, highly transparent, large surface to volume ratio, and 2D quantum - confinement. High transparency LEDs are required for applications in transparent displays on glass panels. Many 2D based opto-electronic devices have used mechanical exfoliation from bulk crystals, but this is limited to small areas. Recent work on - chemical vapour deposition (CVD) to grow wafer-scale 2D materials has opened up exciting opportunities for commercial exploitation and has accelerated the intensity of research in this field towards real applications. The vision of this proposal is - to realize a new class of ultra-thin, flexible, large-area, transparent, high-sensitivity opto-electronic device arrays based on all 2D materials, with a focus on imaging sensors and LEDs. This will involve wafer-scale CVD synthesis of 2D materials - including novel blue and green 2D semiconductors, optical spectroscopy to probe the interlayer interactions, atomic level structure-property correlations using advanced electron microscopy, and the nanoscale fabrication and testing of high efficiency - devices. - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - LATO - - - ERC-2016-COG - - - 725258 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 1 922 575 - - - Surviving metabolism: acid handling and signalling - - - EUR 1 922 575 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Metabolism generates vast quantities of acid, which exerts broad-spectrum biological effects because protein protonation is a powerful post-translational modification. Regulation of intracellular pH (pHi) is therefore a - homeostatic priority, but carefully orchestrated proton dynamics are a versatile signal. - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - Survive - - - ERC-2016-COG - - - 723997 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 1 499 450 - - - The Politics and Practice of Social Media in Conflict - - - EUR 1 499 450 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Over the next five years an unprecedented number of initiatives will coalesce, contributing to an extension of the reach of the Internet to the world’s most remote regions. While previous efforts to expand Internet access have - focused on urban areas, current initiatives are leveraging new technologies from drones to satellites to provide affordable access to the worlds poorest, many of whom are in Africa and live in regions where the state is weak and there is protracted - violent conflict. Current debates have largely focused on technical issues of improving access, or assumed ways that technology will help ‘liberate’ populations or improve governance. This project focuses on a key puzzle that is often overlooked: How - does increased access to social media affect the balance between peace-building efforts and attempts perpetuate violence in conflict-affected communities? - - - 2022-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - ConflictNET - - - ERC-2016-STG - - - 716686 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 1 437 367 - - - Power of Algorithms in Discrete Optimisation - - - EUR 1 437 367 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Convex relaxations, such as linear and semidefinite programming, constitute one of the most powerful techniques for designing efficient algorithms, and have been studied in theoretical computer science, operational research, - and applied mathematics. We seek to establish the power convex relaxations through the lens of, and with the extensions of methods designed for, Constraint Satisfaction Problems (CSPs). - - 2021-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - PowAlgDO - - - ERC-2016-STG - - - 714532 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 1 997 959 - - - Galois theory of periods and applications. - - - EUR 1 997 959 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - A period is a complex number defined by the integral of an algebraic differential form over a region defined by polynomial inequalities. Examples include: algebraic numbers, elliptic integrals, and Feynman integrals in - high-energy physics. Many problems in mathematics can be cast as a statement involving periods. A deep idea, based on Grothendieck's philosophy of motives, is that there should be a Galois theory of periods, generalising classical Galois theory for - algebraic numbers. This reposes on inaccessible conjectures in transcendence theory, but these can be circumvented in many important cases using an elementary notion of motivic periods. This allows one to set up a working Galois theory of periods in - many situations of arithmetic and physical interest. - - 2022-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - GALOP - - - ERC-2016-COG - - - 724638 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 1 999 892 - - - Optical Manipulation of Colloidal Interfaces, Droplets and Crystallites - - - EUR 1 999 892 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This multidisciplinary research programme is focussed on the optical manipulation of interfaces, droplets and crystallites in colloidal model systems. In particular, we will use holographic optical tweezing and confocal - microscopy to study interfacial phenomena in three different phase separated colloid-polymer mixtures, exhibiting colloidal liquid-gas, crystal-gas and nematic-isotropic phase coexistence, respectively. First, we will determine the full potential - energy landscape of the optical traps using the relation between interface fluctuations and deformed liquid-gas interfaces. This will then be used to study the complex and anisotropic interfacial properties of crystal-gas and nematic-isotropic - interfaces. In addition, we envisage quantitatively investigating the nucleation of colloidal liquid droplets, crystallites and liquid crystalline droplets in optical traps positioned at well-defined heights above the interface, which is a direct and - quantitative measure for the undersaturation. This allows us to systematically study the relation between the quench depth, nucleus size and nucleation times. We will furthermore nucleate multiple droplets, crystallites and liquid crystalline - droplets to study their optical trapping controlled coalescence and detachment, which will shed completely new light on for instance the single particle structure and dynamics upon coalescence and detachment. Finally, we will introduce large probe - particles into the phase separated colloid-polymer mixtures, which enables the study of important phenomena such as heterogeneous nucleation and capillary condensation, crystallisation and nematisation. This ambitious project opens up a huge range of - exciting possibilities to gain a deep and fundamental understanding of interfacial phenomena in complex fluids by actively manipulating and controlling colloidal interfaces, droplets and crystallites. - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - OMCIDC - - - ERC-2016-COG - - - 724834 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 1 610 231 - - - Atomic Scale Defects: Structure and Function - - - EUR 1 610 231 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Atomic scale defects play a key role in determining the behaviour of all crystalline materials, profoundly modifying mechanical, thermal and electrical properties. Many current technological applications make do with - phenomenological descriptions of these effects; yet myriad intriguing questions about the fundamental link between defect structure and material function remain. - - 2022-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - AtoFun - - - ERC-2016-STG - - - 714697 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 1 499 429 - - - Heart regeneration in the Mexican cavefish: The difference between healing and scarring - - - EUR 1 499 429 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Whereas the human heart cannot regenerate cardiac muscle after myocardial infarction, certain fish efficiently repair their hearts. Astyanax mexicanus, a close relative of the zebrafish, is a single fish species comprising - cave-dwelling and surface river populations. Remarkably, while surface fish regenerate their heart after injury, cavefish cannot and form a permanent fibrotic scar, similar to the human heart. Using transcriptomics analysis and immunohistochemistry, - we have identified key differences in the scarring and inflammatory response between the surface and cavefish heart after injury. These differences include extracellular matrix (ECM) proteins, growth factors and macrophage populations present in one, - but not the other population, suggesting properties unique to the surface fish scar that promote heart regeneration. The objective of the proposed project is to characterise and utilise these findings to identify therapeutic targets to heal the human - heart after myocardial infarction. First, we will analyse the identified differences in scarring and immune response between the fish in detail, before testing the role of the most interesting proteins and macrophage populations during regeneration - using CRISPR mutagenesis and clodronate liposomes. Next, we will link the key scarring and inflammatory differences directly to both the genome and the ability for heart regeneration using new and prior Quantitative Trait Loci analyses. This will - allow to find the most fundamental molecular mechanisms directing the wound healing process towards regeneration versus scarring. Together with an in vitro and in vivo small molecule screen directed specifically at influencing scarring towards a more - ‘fish-like’ regenerative phenotype in the cavefish and mouse heart after injury, this will provide targets for therapeutic strategies to maximise the endogenous regenerative potential of the mammalian heart, with the aim to find a cure for myocardial - infarction. - - 2022-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - CAVEHEART - - - ERC-2016-STG - - - 715895 - - - - - UNIVERSITY COLLEGE LONDON - UNIVERSITY COLLEGE LONDON - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD - - - EUR 1 499 405,99 - - - Can humans embody augmentative robotics technology? - - - EUR 1 499 405,99 - - - United Kingdom - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Wearable technology is redefining the boundaries of our own body. Wearable robotic (WR) fingers and arms are robots, designed to free up or complement our hand actions, to enhance humans’ abilities. While tremendous resources - are being dedicated to the development of this groundbreaking technology, little notice is given to how the human brain might support it. The intuitive, though unfounded, view is that technology will fuse with our bodies, allowing our brains to - seamlessly control it (i.e. embodied technology). This implies that our brain will share resources, originally devoted to controlling our body, to operate WRs. Here I will elucidate the conditions necessary for technological embodiment, using - prosthetic limbs as a model. I will build upon knowledge gained from rehabilitation, experimental psychology and neuroscience to characterise and extend the boundaries of body representation towards successful adoption of WRs. I will combine - behavioural, physiological and neuroimaging tools to address five key questions that are currently obscuring the vision of embodied technology: What conditions are necessary for a person to experience an artificial limb as part of their body? Would - the resources recruited to control an artificial limb be shared, or rather conflict, with human body representation? Will the successful incorporation of WRs disorganise representations of the human limbs? Can new sensory experiences (touch) be - intuitively inferred from WRs? Can the adult brain support the increased motor and cognitive demands associated with successful WRs usage? I will first focus on populations with congenital and acquired hand loss, who differ in brain resources due to - plasticity, but experience similar daily-life challenges. I will then test body representation in able-bodied people while learning to use WR fingers and arm. Together, my research will provide the first foundation for guiding how to successfully - incorporate technology into our body representation. - - 2022-01-31, ongoing project - - - 2017-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - EmbodiedTech - - - ERC-2016-STG - - - 715022 - - - - - THE UNIVERSITY OF EDINBURGH - - - EUR 183 454,80 - - - Can histone code-like switches govern the multifunctionality of RNA-binding proteins? - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Post-transcriptional control of human gene expression is conferred by >1000 mRNA-binding proteins (RNA-BPs), which determine the utilisation and fate of mRNAs, with the aetiology of a wide-range of disorders (e.g. - neurological, inflammatory, and neoplastic) being due to their dysregulation. - - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - MARS - - - H2020-MSCA-IF-2016 - - - 753803 - - - - - Institut Català de Recerca de l'Aigua, Fundació Privada - Institut Català de Recerca de l'Aigua, Fundació Privada - - - EUR 1 493 734 - - - Three-dimensional nanoelectrochemical systems based on low-cost reduced graphene oxide: the next generation of water treatment systems - - - EUR 1 493 734 - - - Spain - Spain - - - Research Organisations - Research Organisations - - The ever-increasing environmental input of toxic chemicals is rapidly deteriorating the health of our ecosystems and, above all, jeopardizing human health. Overcoming the challenge of water pollution requires novel water - treatment technologies that are sustainable, robust and energy efficient. ELECTRON4WATER proposes a pioneering, chemical-free water purification technology: a three-dimensional (3D) nanoelectrochemical system equipped with low-cost reduced graphene - oxide (RGO)-based electrodes. Existing research on graphene-based electrodes has been focused on supercapacitor applications and synthesis of defect-free, superconductive graphene. I will, on the contrary, use the defective structure of RGO to induce - the production of reactive oxygen species and enhance electrocatalytic degradation of pollutants. I will investigate for the first time the electrolysis reactions at 3D electrochemically polarized RGO-coated material, which offers high catalytic - activity and high surface area available for electrolysis. This breakthrough approach in electrochemical reactor design is expected to greatly enhance the current efficiency and achieve complete removal of persistent contaminants and pathogens from - water without using any chemicals, just by applying the current. Also, high capacitance of RGO-based material can enable further energy savings and allow using intermittent energy sources such as photovoltaic panels. These features make 3D - nanoelectrochemical systems particularly interesting for distributed, small-scale applications. This project will aim at: i) designing the optimum RGO-based material for specific treatment goals, ii) mechanistic understanding of (electro)catalysis - and (electro)sorption of persistent pollutants at RGO and electrochemically polarized RGO, iii) understanding the role of inorganic and organic matrix and recognizing potential process limitations, and iv) developing tailored, adaptable solutions for - the treatment of contaminated water. - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Spain - - - ELECTRON4WATER - - - ERC-2016-STG - - - 714177 - - - - - KOBENHAVNS UNIVERSITET - - - EUR 212 194,80 - - - The Importance of Barriers to Bird Migration - - - EUR 212 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - Understanding animal migration is one of the most compelling and challenging problems of modern biology. For a long time, we have been hindered by the large geographical scale of migratory movements and the small sizes of most - migratory animals. Crossing barriers is a fundamental aspect of animal migration. Long-distance migratory birds face crossings of formidable barriers such as the Sahara Desert, Himalaya Mountains, or the Pacific Ocean twice a year, but even - short-distance migrants travel across inhospitable habitats. Successful migration, and specifically successful barrier crossings, depend on the availability of favourable weather conditions aloft and suitable habitat during stopovers. Surprisingly - little is known about the behaviours that guide billions of avian migrants to a successful barrier crossing. Advances in tracking technology and remote sensing now offer us new tools to track small migratory animals with extraordinary precision. I - will use these new methods to study how nocturnally migrating songbirds manage barriers during their migration. With this action I aim to increase the understanding of (1) the behavioural strategies that birds use to negotiate large geographic - features and (2) how barriers limit bird migration. The research will be conducted under PI Prof. Kasper Thorup in the Bird Migration Lab, Center for Macroecology, Evolution and Climate, at the University of Copenhagen. Prof. Thorup’s group has - advanced the front of global scale tracking of avian migration for the last decade, and possess the necessary expertise in spatiotemporal patterns. Further, I will spend a secondment at the Institute of Avian Research, Germany, and gain from Dr. - Heiko Schmaljohann expertise in stopover behaviour. By combining my existing expertise in radiotelemetry tracking and migratory behaviour, with new skills in additional tracking techniques and analytic tools, this action will advance the research - field and enhance my career as independent researcher. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - BIRDBARRIER - - - H2020-MSCA-IF-2016 - - - 751692 - - - - - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - - - EUR 171 460,80 - - - Road Diplomacy: International Infrastructure and Ethnography of Geopolitics in 21st Century Asia - - - EUR 171 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - The objective of this project is to understand where, why, and to what extent roads are being built between China and South Asia and to untangle the inter-related geopolitical and social impacts of infrastructure development - at village, national, and international scales. The project will first map road developments throughout the trans-Himalaya and second investigate the geopolitical drivers and social impacts of road construction. By combining innovative methods from - geography, anthropology, and international relations, I will produce new empirical data on infrastructure development in 21st century Asia and illustrate the links between macro geopolitical processes and micro local experiences. Datasets will - improve interdisciplinary communications for social scientists and between development practitioners, donor agencies, policymakers, and local stakeholders. The research is of relevance to EU citizens because understanding contemporary dynamics - between rising powers like China and India provides context on 21st century global politics and will inform decision-making for EU investment and development interventions in Asia. - - 2020-05-31, Grant Agreement signed - - - 2018-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - Road Diplomacy - - - H2020-MSCA-IF-2016 - - - 751131 - - - - - STICHTING KATHOLIEKE UNIVERSITEIT - - - EUR 162 864,60 - - - Structure-function analysis of the calcium channel TRPV5 - - - EUR 162 864,60 - - - Netherlands - - - Higher or Secondary Education Establishments - - Ion channels are proteins composed of a hydrophillic pore that facilitate ion flow across a plasma membrane. This ionic permeability is controlled by a set of essential properties affecting the channel activation and - inactivation in response to voltage, ligands, or intracellular second messengers. The focus of the present project proposal, the transient receptor potential vanilloid channel (TRPV5), forms a specific category within the large TRP familiy of ion - channels as it comprises a unique high selectivity for calcium ions together with a calcium-dependent inactivation mechanism that is incompletely understood. Detailed analysis of the TRPV5 channel will provide new structural insights into channel - gating that can be extrapolated to other TRP channels, as the current knowledge on the TRP protein structure and its impact on the regulation of the channel function is still limited. - - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Netherlands - - - CRYO-EM TRPV5 - - - H2020-MSCA-IF-2016 - - - 748058 - - - - - KATHOLIEKE UNIVERSITEIT LEUVEN - - - EUR 160 800 - - - Conflicts in start-ups: coping with stress and conflicts to promote well-being and entrepreneurial success - - - EUR 160 800 - - - Belgium - - - Higher or Secondary Education Establishments - - Start-ups are Europe’s 2020 Priorities for strengthening economic growth. However, about 50% of new European businesses fail during their first five years, conflicts between founders and effects of work stress being two of the - top reasons for failure. However, conflicts and stress in start-ups, as well as factors for their entrepreneurial success are under-studied. - - - 2020-01-01, ongoing project - - - 2018-01-02 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Belgium - - - Starflict - - - H2020-MSCA-IF-2016 - - - 745947 - - - - - KATHOLIEKE UNIVERSITEIT LEUVEN - - - EUR 160 800 - - - Investigating the interplay between VWF, platelets, and neutrophil extracellular traps inpathologies involving thrombosis of the microvasculature - - - EUR 160 800 - - - Belgium - - - Higher or Secondary Education Establishments - - Thrombosis is a complex process involving activation of endothelial cells, and their release of Weibel-Palade body contents such as von Willebrand factor (VWF) and P-selectin. This in turn recruits platelets which form - aggregates, and leukocytes such as neutrophils. The recent discovery of neutrophil extracellular traps (NETs) described a novel antimicrobial function of neutrophils. NETs are extracellular chromatin strands containing microbicidal proteins. The - release of histones, serine proteases, and myeloperoxidase concentrated on DNA fibers into the extracellular space can contribute to many pathologies. NETs can bind platelets and red blood cells and therefore also contribute to thrombosis. Activated - platelets can in turn stimulate neutrophils to make NETs, creating a vicious thrombo-inflammatory cycle. - - - 2019-10-02, ongoing project - - - 2017-10-03 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Belgium - - - VWF and NETs - - - H2020-MSCA-IF-2016 - - - 747993 - - - - - UNIVERSITE GRENOBLE ALPES - - - EUR 173 076 - - - Multi-Terminal Josephson Junctions as a novel platform for high dimensional topological matter - - - EUR 173 076 - - - France - - - Higher or Secondary Education Establishments - - The spectrum of Andreev bound states in N-terminal Josephson Junctions (MulTJJ) may be viewed as a pseudo-bandstructure of N-1 dimension Bloch electrons. As we recently showed this pseudo-bandstructure may have interesting - topological properties. (i) Topological transitions between ground states with different fermion parity may occur in a 3-terminal JJ upon varying the superconducting phases. (ii) In 4- or more terminal JJs, the pseudo-bandstructure may display Weyl - nodes, that entail a non-trivial 1st Chern number in a 2D plane in the space of SC phase differences and lead to a measureable quantized transconductance under DC-bias voltage. - - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - TopoInMulTermJJ - - - H2020-MSCA-IF-2016 - - - 753906 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 195 454,80 - - - Theranostic molecular zipper based switchable nanomedicine for overcoming drug resistance - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - This Fellowship will bring an outstanding researcher from Sweden to the UK to gain new scientific and career skills to position him to become a leading independent academic in the interface of chemistry and biology for - translational Nanomedicine. The fellow will design a new class of biomimetic zipper nano-architecture, combining an MRI-enabled SPION scaffold with a zip-unzip, temperature and pH-responsive multi-arm polymer to defuse drug resistant cell functions. - These approach could greatly benefit the current investigation of new and alternate therapeutic procedures to overcome drug resistance. The fellow will gain advanced training in translational designs of drugs for recognition and treatment of drug - resistant system, and in state of the art techniques for studying such system. - - 2019-04-14, ongoing project - - - 2017-04-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - NinZA - - - H2020-MSCA-IF-2015 - - - 706694 - - - - - KOBENHAVNS UNIVERSITET - - - EUR 212 194,80 - - - Structural Dynamics of Membrane Receptors at native-like conditions - - - EUR 212 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - Proteins embedded in cell membranes are vital signaling and trafficking platforms connecting the outside to the inside of a cell, and functioning as primary drug targets. DYNAMO is an integrative dynamic structural biology - project, with the ambitious goal of developing and implementing comprehensive experimental and computational approaches for studying the structural dynamics of membrane receptors (MRs) and their complexes at native-like conditions. DYNAMO is highly - interdisciplinary, combining protein chemistry and computational physics to study dynamical processes underlying the function of MRs, and is designed to combine the expertise of the fellow and host. The project will establish an integrated platform - based on the nanodisc-technology and the combined use of low- and high-resolution structural biology techniques to bring unique and alternative insights into the structural dynamics of MRs containing ”fuzzy” (i.e highly flexible) domains, and the - role this plays in functional signaling assemblies. In order to broaden the scope of the project and secure a general applicability of the developed methodology, full-length tissue Factor (TF) and Ghrelin receptor (GHS-R1a) are selected as models of - single-pass and multi-pass MRs. These MRs do not only display different topologies and functional assemblies but also different selectivity towards lipids. TF and GHS-R1a are central to blood coagulation and energy homeostasis, respectively, and also - connected to genetic and metabolic disorders, and thereby not only relevant as model systems but also promising drug targets. The project will exploit the recent advances in SAXS/SANS- and NMR-based methods to study the TF and GHS-R1a in nanodiscs, - with an emphasis on their conformational ensemble nature. Upon the establishment of the methodology, it will be extended to study the interaction with their endogenous ligands. - - 2020-02-29, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - DYNAMO - - - H2020-MSCA-IF-2016 - - - 753487 - - - - - THE UNIVERSITY OF EDINBURGH - THE UNIVERSITY OF EDINBURGH - - - EUR 1 199 805 - - - International Organisations and the Rise of a Global Metrological Field - - - EUR 1 199 805 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The production of global metrics by International Organisations has not only penetrated the transnational social and policy fields; it has also become an integral mode of the ways International Organisations interconnect. - Through their collaborative practices of quantification and commensuration, International Organisations are both constituting new realities and being reconstituted themselves. Thus, the dominance of global measurement regimes has profound - implications for the ways International Organisations interact, and for the environments these new interrelationships come to generate. - - - 2021-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - METRO - - - ERC-2016-STG - - - 715125 - - - - - SIEMENS HEALTHCARE GMBH - - - EUR 171 460,80 - - - Matched Sampling Approaches for Statistical Inference in Large-Scale Clinical Neuroimaging Studies - - - EUR 171 460,80 - - - Germany - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Noninvasive neuroimaging techniques have shown much promise over the last decade in the investigation, diagnosis and in determining treatment of neurological disorders. However, to improve their predictive power and better - understand underlying causative disease factors it will be essential to extend our investigations to empiric studies of large populations and to develop appropriate statistical models and define statistical procedure for use in such observational - studies. It is the main objective of this project therefore, to develop and extend the methods of Causal Inference for use on large unstructured neuroimaging datasets. Specifically, this proposal seeks to 1) Develop and apply existing techniques from - matched sampling to observational studies of imaging for Causal Inference. 2) Investigate the benefits of the same matched sampling procedures in support of classification models. 3) Industrial considerations: This is an enterprise panel proposal and - will aim to integrate the developed technology into the Clinical Imaging Big-Data program at Siemens HealthCare (SHC), Erlangen. These objectives will be achieved by implementing and testing different Matched Sampling procedures using large - observational neuroimaging datasets and assessing their performance through reduction in the specific forms of bias known to be present in observational data. These methods will be extended for use in classification models and the effects of matching - on common prediction methods will be examined. The project is highly relevant for the work program as it will provide an opportunity to enhance training through Siemens and has the potential to facilitate a career move from academia to the non - academic sector. - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-SE - Society and Enterprise panel - - - Germany - - - zelig - - - H2020-MSCA-IF-2016 - - - 752652 - - - - - UNIVERSITY OF YORK - - - EUR 183 454,80 - - - Ovine origins and diversity in north-eastern Europe - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Sheep (Ovis aries) is one of the most important and widely distributed domestic species worldwide according to the Food and Agriculture Organization of the United Nations (FAO), and considered one of the ‘big five’ livestock - species alongside cattle, goat, pig and chicken. The high number of sheep breeds with worldwide distribution, and the 11,000 years alongside humans makes them a fascinating, yet difficult species to study. Important information on the history of - domestic sheep has been obtained from ancient faunal remains using ‘traditional’ zooarchaeological methods based on osteology and morphology, with relatively less little contribution from ancient genetics, compared to domesticates such as dogs or - horses. OVinE will train the early researcher Eve Rannamäe in state-of-the art methods from zooarchaeology and ancient genomics to document the introduction, spread, and development of domestic sheep. Focusing on north-eastern (NE) Europe, where - studies on sheep history and diversity are scarce compared to the rest of Europe, but where the extant indigenous breeds are highly valued for their genetic diversity, OVinE will: 1) clarify the timing and origins of the first sheep in NE Europe; 2) - decipher the development and improvement of sheep populations from the Late Neolithic (c. 3000–1800 BC) through to the Modern period (AD 1800–1950); 3) clarify the affinities between ancient sheep populations and local indigenous breeds. - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - OVinE - - - H2020-MSCA-IF-2016 - - - 749226 - - - - - TRAPEZA TIS ELLADOS AE - - - EUR 152 653,20 - - - The Role of Global and Sectoral Factors in Labour Share Fluctuations - - - EUR 152 653,20 - - - Greece - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - This project will investigate the distribution of national income between profits and wages as proxied by the labour share in national income. The focus will be to identify the empirical regularities of factor shares in - developed and emerging countries and across industries. In 1957, Kaldor established an influential stylised fact for macroeconomic modelling: the stability of the labour share. This finding, which has implications for macroeconomic dynamics, the - shape of the production function and inequality, led social scientists to become 'silent' and to neglect research on labour share for many decades. Standard neoclassical growth and business cycle models, following Kaldor’s stylised fact, assume a - one-to-one substitution between capital and labour. However, the recent observation of a declining labour share points to an incomplete understanding of macroeconomic dynamics and to potentially erroneous policy implications drawn from these models. - This has renewed the interest of macroeconomists to unveil the sources driving this decline. The proposed study on the fluctuations of the labour share from a solid empirical standpoint will provide the broad social science academic community and the - policymakers with a better understanding of the behaviour of the labour share. In particular, this project aims at (i) reconciling the existing literature on the sources of labour share decline by examining a large set of driving forces and their - relationship to key macroeconomic variables; (ii) providing a descriptive analysis of labour share from a multi-sector and multi-country perspective; as well as, a decomposition of labour share into national and external factors. This project will - thus strictly link academic literature and policymakers’ interests with issues such as what should be the appropriate response of governments to the observed decline of the labour share and its implications for fiscal and monetary policy. - - 2019-07-02, ongoing project - - - 2017-07-03 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-SE - Society and Enterprise panel - - - Greece - - - GaSLS - - - H2020-MSCA-IF-2016 - - - 746100 - - - - - UNIVERSITY OF DURHAM - - - EUR 183 454,80 - - - Church Building as Industry in Early Medieval Western Europe - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - This project interrogates the early medieval ‘construction industry’ with a specific focus on the ecclesiastical workshops responsible for producing masonry buildings in the Early Middle Ages (8th-11th centuries). Using - state-of-the-art analyses of selected religious buildings that survive as standing structures in Spain, Portugal and England, the overarching aims of the proposal are threefold. Firstly, to study the industry of construction of masonry churches - through analysis of the building processes, technologies and the material and skills-based investment at selected churches. Secondly, to develop an understanding of the architecture as a product in its social and economic context, and to measure its - contribution to the early medieval economy. Thirdly to establish a suitable methodology for the analysis of the construction industry at this time across Western Europe. The combination of traditional and novel methodologies, including architectural - archaeology, history, geology, cost calculations, structural analysis and reverse engineering will facilitate a new assessment of Early Medieval church-building programmes, offering a unique opportunity to redefine the economy and history of the - Middle Ages by taking into account this industry in the context of other industrial sectors, charting the period from a new perspective and transcending the boundaries of traditional research. As part of the research programme, the candidate will - acquire complementary knowledge in the field (mainly relating to Anglo-Saxon architecture), will be trained in new techniques (OSL, laser scanning, GIS/informatics and LiDAR) and will interact with researchers in the host organisation who have - mutually complementary research expertise. Results will be disseminated by via a monograph and papers published in high-impact journals, and communicated to public by means of different activities. - - 2018-08-31, Grant Agreement terminated - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - CHISEL - - - H2020-MSCA-IF-2015 - - - 702350 - - - - - UNIVERSITA DEGLI STUDI ROMA TRE - ISTANBUL TEKNOKENT ANONIM SIRKETI - UNIVERSITEIT UTRECHT - DISTRETTO AGROALIMENTARE REGIONALE SCRL - VILNIAUS GEDIMINO TECHNIKOS UNIVERSITETAS VIESOJI ISTAIGA - REDINN SRL - ACADEMY OF SCIENTIFIC RESEARCH AND TECHNOLOGY ASRT - UNIVERSITE SIDI MOHAMMED BEN ABDELLAH - - - EUR 796 500 - - - Cluster Development Med - - - EUR 796 500 - - - Italy - Turkey - Netherlands - Italy - Lithuania - Italy - Egypt - Morocco - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Other - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The proposal lies within priority research & innovation topics in EU-Mediterranean cooperation, as highlighted in several past projects and policies reccomendations, i.e. within the MOCO - Monitoring Committee for - Euro-Mediterranean Cooperation in RTD. International Cluster Cooperation offers opportunities to scal up research and technological potential, enhance competitiveness, support the regional socio-economic development and reinforce the market placement - of new, innovative products. These cooperation approaches often fail due to constraints on resources, capabilities, instruments and funding. On the other hand, over 2.000 Clusters only in the European Union covering all sectors and able to realize an - intersectorial framework, as well as related clusters and networks in the southern Mediterranean countries, form a great potential for transnational clustering. - - - 2019-05-31, ongoing project | - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Italy - - - CLUSDEV MED - - - H2020-MSCA-RISE-2014 - - - 645730 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 170 121,60 - - - Titanium Oxide Nanocomposites for Scalable Optimized Perovskite Solar cells - - - EUR 170 121,60 - - - Spain - - - Research Organisations - - The European commission recognizes the importance of nanotechnology, semiconductors and advanced materials as key enabling technologies. The application of functional nanostructured materials in industrial processes and - advanced science is of capital and strategic importance for the European economy and society. Their inclusion as reliable, standard and affordable components will boost the competitiveness of European industry, specifically in the fabrication of 4th - generation solar cells. Sensitized Perovskites Solar cells (PSC) represent advantages in terms of cost manufacturing, energy generation and integration in flexible and semitransparent devices. However, the viability of their mass scale fabrication is - hindered by economic and technical difficulties. Some of these technical issues arise from inefficient infiltration of the perovskite absorber into a fragile mesoporous (mp) TiO2 layer. My project addresses these problems applying a recently - developed straightforward method for secure TiO2 nanotube layers (TNL) to commodity thermoplastic polymers. This novel method combined with optimized solution synthesized perovskites will result in the production of flexible and pliable PSC. - Specifically, I propose to produce a step change in the standardization and fabrication of functional nanostructured materials, and its implementation in optimized PSCs. Lastly, the study on the life cycle management and viability of the industrial - production of these PSC will be evaluated in an innovative photovoltaic manufacture company, ONYX SOLAR. Hence, the project is designed to generate disruptive, but easily scalable technology that may be rapidly adopted by European industry to boost - its competitiveness in functional nanostructured composites and 4th generation solar cells. - - 2018-03-15, Grant Agreement terminated - - - 2016-03-16 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - TONSOPS - - - H2020-MSCA-IF-2015 - - - 706094 - - - - - UNIVERSITAET INNSBRUCK - UNIVERSITATEA DIN BUCURESTI - Instituto de Educação da Universidade de Lisboa - DOLNOSLASKA SZKOLA WYZSZA - EOTVOS LORAND TUDOMANYEGYETEM - Masarykova univerzita - - - EUR 3 472 230,24 - - - European Joint Doctorate in Teacher Education - - - EUR 3 472 230,30 - - - Austria - Romania - Portugal - Poland - Hungary - Czech Republic - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The EDiTE joint research programme is a response to the current challenges in the complex processes of transformation of education professionals' career development. Particularly in focus is the teaching profession as central - to all education systems. In the research area it is essential that typical national or regional perspective found in TE programmes are extended to include transnational perspectives. A European perspective on the academic level can only be fostered - through joint European research. - - 2019-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-EJD - Marie Skłodowska-Curie Innovative Training Networks (ITN-EJD) - - - MSCA-ITN-EJD - European Joint Doctorates - - - Austria - - - EDiTE-EJD - - - H2020-MSCA-ITN-2015 - - - 676452 - - - - - HELSINGIN YLIOPISTO - ILMATIETEEN LAITOS - - - EUR 191 325,60 - - - The Foreshock and its Role in Solar-Terrestrial relations - - - EUR 191 325,60 - - - Finland - Finland - - - Higher or Secondary Education Establishments - Research Organisations - - There is a critical need for accurate space weather forecasting, due to the growing use of technologies vulnerable to space weather hazards. However, refining the current models requires a more detailed understanding of - solar-terrestrial relations, especially during extreme events such as magnetic clouds (MCs) which drive the fiercest storms at Earth. To this end, FRoST will investigate a previously unexplored aspect of the interaction of MCs with the terrestrial - environment: the role played by the foreshock, a turbulent region extending upstream of the Earth's bow shock. The objectives of FRoST are (1) to characterise the foreshock properties during MC events, (2) to investigate how these alter in turn the - properties of the region at the interface between the solar wind and the magnetosphere, the magnetosheath, and (3) assess whether the influence of the foreshock can be significant and thus should be included in space weather models. To undertake this - challenging task, we will take on an interdisciplinary approach, combining numerical simulations and spacecraft observations. - - - 2019-03-14, ongoing project - - - 2017-03-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Finland - - - FRoST - - - H2020-MSCA-IF-2015 - - - 704681 - - - - - STICHTING VUMC - STICHTING VU - - - EUR 177 598,80 - - - Responding or not responding to training; prediction of balance rehabilitation outcome from structural and functional brain networks in Cerebral Palsy. - - - EUR 177 598,80 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - When an injury occurs to the developing brain, as in Cerebral Palsy (CP), these children typically experience sensorimotor disorders such as muscle weakness, abnormal muscle activity, and ataxia. Poor balance control is a - primary deficit in CP, which has a large impact on a child’s daily life, since it is crucial for independent mobility and greatly affects the risk of falls. CP is the most common developmental cause of physical disability in the world, with a - prevalence of 2-3 in 1000 live births. To improve their quality of life, adequate treatment is essential. However, studies investigating the effectiveness of balance rehabilitation in CP have revealed mixed results. This is due to two reasons. First, - due to the various clinical scales and experimental measures available, each measuring different components of balance, it is very complex to diagnose balance control in CP. Second, it is currently unknown which are the underlying neural causes of - poor balance control in CP. - - 2018-02-28, Grant Agreement terminated | - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - CP-RehOP - - - H2020-MSCA-IF-2014 - - - 660458 - - - - - UNIVERSITY COLLEGE LONDON - - - EUR 195 454,80 - - - Profiting from ECO-innovation: the RolE of BUSiness model - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - ECO_REBUS aims to get a closer understanding of the process through which firms adopt and operate public voluntary eco-innovation policies, a kind of policy that has become increasingly central in policy makers’ agenda. To - achieve this objective, the project assigns a specific role to the concept of business model, defined as the configuration of customer sensing, customer engagement, value delivery and monetization components, that captures causal links between value - creation and value capture at the business level. Specifically, the project will integrate the literature on eco-innovation and the one on business model to address how and why business model can make eco-innovation a central part of the firm’s value - creation and appropriation. To do this, ECO_REBUS will investigate -by a cognitive and processual perspective- the phases through which public voluntary eco-innovation policies are adopted and operated by firms. - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ECO_REBUS - - - H2020-MSCA-IF-2016 - - - 753274 - - - - - UNIVERSITE PARIS DIDEROT - PARIS 7 - - - EUR 173 076 - - - Rule-algebraic Simple Rewriting - - - EUR 173 076 - - - France - - - Higher or Secondary Education Establishments - - The basis for this project consists in a mathematical framework previously developed by the applicant that allows to describe graph rewriting systems algebraically, the so-called rule algebraic framework. In order to advance - and valorise the concept, this project proposes to develop a general concept for rule-algebraic simple rewriting (RaSiR), both for conventional graph rewriting and for a novel form of simplicial rewriting. Secondly, RaSiR will serve as the basis for - developing rule-algebraic variants of trace compression and observable-update algorithms for the rewriting system Kappa. The final aim of the project consists in developing and implementing the so-called observable-centric bootstrapping algorithm - (OCBA) as a module for the simulation suite KaSim for the Kappa language. Kappa is predominantly used for simulating biochemical reaction systems, which typically display an extremely high combinatorial complexity. The algorithms and software modules - developed in this project will provide in particular an alternative to pure stochastic simulation via the SSA algorithm as currently implemented in KaSim, in the form of the OCBA module. This module will admit the generation of approximate observable - distributions from individual pure states of the system by calculating algebraically truncations of the formal solution of the chemical master equation as well as the induced observable update functions. The project shall be hosted by Dr. Jean - Krivine of the PPS team at IRIF at the University Paris-Diderot in France. Dr. Krivine is one of the two main developers of the KaSim simulation suite, and moreover one of the world experts in the theoretical and practical development of the - programming language Kappa. IRIF will provide an ideal environment for the applicant to develop new skills, to be part the very interdisciplinary research team PPS, and to communicate and valorise the project results to the greater biochemical and - systems biological simulation community. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - RaSiR - - - H2020-MSCA-IF-2016 - - - 753750 - - - - - HELMHOLTZ-ZENTRUM BERLIN FUR MATERIALIEN UND ENERGIE GMBH - HELMHOLTZ-ZENTRUM BERLIN FUR MATERIALIEN UND ENERGIE GMBH - - - EUR 1 987 500 - - - Multiscale modelling of stimuli-responsive nanoreactors - - - EUR 1 987 500 - - - Germany - Germany - - - Research Organisations - Research Organisations - - The catalysis by metal nanoparticles is one of the fastest growing areas in nanoscience due to our society's exploding need for fuels, drugs, and environmental remediation. However, the optimal control of catalytic activity - and selectivity remains one of the grand challenges in the 21st century. - - 2020-07-31, ongoing project - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - NANOREACTOR - - - ERC-2014-CoG - - - 646659 - - - - - UNIVERSITEIT ANTWERPEN - - - EUR 160 800 - - - Novel electrochemical strategies for rapid, on-site multiscreening of illicit drugs - - - EUR 160 800 - - - Belgium - - - Higher or Secondary Education Establishments - - Drug use continues to be a problem of major concern for public authorities worldwide. According to the World Drug Report elaborated by the United Nations Office of Drugs and Crime (UNODC) approximately 207,000 drug-related - deaths occur per year. With between 162 million and 324 million people aged 15-64 having used an illicit drug — mainly substances belonging to canabinoids, opioids, cocaine or amphetamine-type stimulants group — at least once in the previous year, - drug abuse continues to have devastating consequences on human health. - - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Belgium - - - NARCOREADER - - - H2020-MSCA-IF-2016 - - - 753223 - - - - - UNIVERSITAT AUTONOMA DE BARCELONA - - - EUR 158 121,60 - - - Unfair transitions? A critical examination low-carbon energy pathways in the EU from a domestic energy vulnerability perspective - - - EUR 158 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - Energy transitions towards sustainability are driven by the need to reduce the environmental impacts of energy consumption, namely those related to carbon emissions. However, it is feared that a large scale deployment of - low-carbon solutions that disregards pre-existing socio-economic and material inequalities may result in transitions deepening disparities or creating new energy-related vulnerabilities. Such prospect is particularly worrying as tens of millions of - EU households are currently experiencing energy poverty, i.e., they are unable to access socially- and materially-necessitated levels of domestic energy services. Against this background TRANSFAIR aims to identify, conceptualise and empirically - substantiate the ways in which the EU’s “transition to a low-carbon, secure and competitive economy” may (or not) be reproducing and reinforcing current energy vulnerability trends in Member States. To this end the research will combine the political - ecology and environmental justice frameworks with transitions theory and multi-level governance perspective, conduct a critical, integrative review of scientific and policy literature and carry out an empirically-based examination of two - complementary case studies: renewable electricity cooperatives in Spain and advanced thermal retrofits of multi-family buildings in Hungary. - - - 2020-01-01, ongoing project - - - 2018-01-02 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - TRANSFAIR - - - H2020-MSCA-IF-2016 - - - 752870 - - - - - TECHNISCHE UNIVERSITEIT DELFT - - - EUR 165 598,80 - - - Understanding nitrogen metabolic interactions in mixed anammox-based microbial communities - - - EUR 165 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Improving current biological wastewater treatment plants (WWTPs) towards more reliable and resource-efficient solutions is a priority of the EU (Water Framework Directive). Successful biological treatments rely on the - concerted activity of different microorganisms and thus optimized microbial community engineering strategies are required to achieve this goal. Processes based on anammox bacteria hold promise to reduce the energy and resource expenditures of WWTPs. - However, our current knowledge of the different microorganisms involved and the environmental factors regulating their interactions in anammox-based microbial communities remains limited. The MixAmox project aims at advancing our fundamental - understanding of the metabolic interactions and their implications for process performance in these communities through a multidisciplinary approach based on theoretical and experimental methods combined with cutting-edge molecular techniques and - stable isotopes. The obtained results are expected to foster the implementation of anammox systems. Moreover, the developed methodological framework will be directly applicable for the study of any natural or engineered complex microbial community. - - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - MixAmox - - - H2020-MSCA-IF-2016 - - - 752992 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 171 349,20 - - - Chimeric Antigen Receptor to generate Alloantigen-specific Regulatory T cells and promote allograft tolerance - - - EUR 171 349,20 - - - France - - - Research Organisations - - Organ transplantation is the best life-supporting treatment for terminal organ failure. Graft survival is however limited by rejection, a destructive process resulting from the response of recipient’s immune system against - donor specific alloantigens. Prevention of rejection currently relies on immunosuppressive drugs that lack antigen specificity and therefore increase the risk for infections and cancers. Induction of donor-specific tolerance would provide indefinite - graft survival without morbidity and therefore represents the Grail of transplant immunologists. - - - 2019-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - France - - - CAR ART - - - H2020-MSCA-IF-2016 - - - 752869 - - - - - TECHNISCHE UNIVERSITEIT DELFT - TECHNISCHE UNIVERSITEIT DELFT - WAGENINGEN UNIVERSITY - - - EUR 1 499 183,75 - - - Adaptive immunity in prokaryotes: how Bacteria do not forgive and do not forget their enemies - - - EUR 1 499 183,75 - - - Netherlands - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Microbes in natural ecosystems are under constant evolutionary pressure from viruses. To survive in this hostile environment microbes have evolved an adaptive immune system called CRISPR-Cas. The immune system is based on - incorporation of invader DNA sequences in a memory locus (CRISPR), the formation of guide RNAs from this locus, and the degradation of invading target DNA using CRISPR RNA-guided protein complexes. Invaders escape immunity by making point mutations - in the targeted region of their DNA, but hosts quickly restore immunity by integrating new memory sequences against the same invader in a process called priming. Recently, I have made the remarkable discovery that hosts mount a primed immune response - even when facing heavily mutated invaders. This implies that the memory of the CRISPR-Cas system not only functions in the short term against relatively recent threats, but also remembers a range of revisiting old foes in the long term, providing a - huge evolutionary benefit for the host in the arms race with their invaders. - - 2020-05-31, ongoing project | - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - REMEMBER - - - ERC-2014-STG - - - 639707 - - - - - THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS - - - EUR 183 454,80 - - - Origins of theory of mind: action prediction by great apes and human infants - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Theory of mind (ToM) is the ability to impute unobservable mental states, such as desires and beliefs, to others. Our inferences about what others are thinking allow us to deceive and to empathize, to cooperate and to teach. - For four decades, researchers have been attempting to elucidate the evolutionary and ontogenetic origins of this critical cognitive ability. In conflict with a long-held consensus, some have begun to argue that human infants (and to some extent great - apes) share with human adults even the most cognitively sophisticated representational ToM abilities. To help resolve the intense resulting debate, this proposal presents a series of targeted experiments to test for several understudied but key ToM - skills in great apes and human infants. The skills in question—attribution of (a) unfamiliar desires, (b) ignorance, and (c) false perceptions—form the basis of an organism’s ability to distinguish others’ minds from its own and build sequentially in - terms of their cognitive and representational underpinnings. The present proposal marshals innovative new anticipatory looking eye-tracking methods and the most auspicious conditions available worldwide, through support of esteemed comparative and - developmental psychologists Profs Josep Call and Malinda Carpenter and the School of Psychology and Neuroscience at the University of St Andrews, to address these major gaps in the social cognitive literature. The proposal’s novel anticipatory - looking methods, which assess participants’ predictions based on their looks in anticipation of agents’ acting on specific locations or objects, combine low task demands (like VoE paradigms) with clearer interpretability (much like action-based - tasks). The proposal thus offers powerful tests of the hypotheses that great apes and human infants share with human adults a representational theory of mind. These studies will contribute key data to our understanding of the ontogenetic and - evolutionary precursors of the human mind. - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - MENTALIZINGORIGINS - - - H2020-MSCA-IF-2016 - - - 752373 - - - - - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - - - EUR 187 419,60 - - - Synthesis of Low Noise Microwaves Using Solitons Locked to an Ultra-Stable Cavity - - - EUR 187 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - This project (SOLISYNTH) aims to utilize the novel crystalline microresonator optical frequency comb to synthesize ultra-stable microwaves. The microresonator comb will operate in the state of temporal dissipative soliton and - an ultra-stable Fabry-Perot cavity will be used as a reference for the comb to lock to. By using direct optical division with the comb, this work could offer a new approach to synthesize low-phase-noise microwaves in a compact form factor, which - could have applications in Radar, timing and telecommunications to radio astronomy. In addition, this project seeks to generate mid-infrared soliton comb with octave spanning bandwidth through dispersion engineering and quantum cascade laser pumping. - With its exceptionally high coherence, such frequency comb offers access to the molecular fingerprinting region where many chemical species show distinctive absorption features. Devices based on this research output can find tremendous applications - in mining, agriculture and medical diagnosis. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - SOLISYNTH - - - H2020-MSCA-IF-2016 - - - 753749 - - - - - BASF SE - - - EUR 159 460,80 - - - Functional Low-Intensity Light Upconverting Inks for Everyday Applications - - - EUR 159 460,80 - - - Germany - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Spectral downconversion of visible or UV-light, that is the transformation of high-energy light into lower energy radiation, is used for a broad range of commercial products or applications and is therefore part of everyday - life of most people. For example, highlighter pen inks contain organic dyes able to transform ambient UV-light into visible radiation making surfaces such as paper or fabric look bright. In contrast, optical effects based on light upconversion, that - is the transformation of low-energy light into higher energy radiation, have barely been investigated since solid-state materials efficiently upconverting light at low intensities (< 100mW·cm-2) are only slowly emerging. - - 2020-02-14, Grant Agreement signed - - - 2018-02-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-SE - Society and Enterprise panel - - - Germany - - - FLUID - - - H2020-MSCA-IF-2016 - - - 752143 - - - - - UNIVERSITY OF LINCOLN - - - EUR 183 454,80 - - - Global Ecological Custodianship: Innovative International Environmental Law for theAnthropocene - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - International environmental law (IEL), with multilateral environmental agreements (MEAs) as its main component, has not been able to address the underlying causes that are responsible for the socio-ecological crisis of the - Anthropocene and it seems unable to respond to this crisis. By providing the fellow with a sustained opportunity to interrogate IEL’s principal MEAs in the context of the Anthropocene, this project seeks to investigate a) the normative implications - of the Anthropocene for law and IEL specifically; b) explain why and to what extent MEAs have contributed, and have been unable to respond to, the Anthropocene’s socio-ecological crisis; and c) to propose a global ecological custodial framework of - care (GLEC-Law) to reform these MEAs. Lawyers have been unable to present a comprehensive solution to MEAs' deficiencies and failures, while Anthropocene scientists have been unable to meaningfully translate their insights into the juridical domain. - Responding to this knowledge gap, this multi-disciplinary project brings together an experienced researcher and an internationally recognized research group with global expertise to problematize the failures, deficiencies and potential of MEAs in the - Anthropocene and to propose reforms of these MEAs. The fellow brings expertise on environmental law, governance and constitutionalism to the host and secondment institutions, including access to global and global South networks, while contributing to - establishing the host as a leading multi-disciplinary European center of excellence in law, governance and Anthropocene studies. The fellow will gain methodological and doctrinal training in IEL and Anthropocene related sciences. The project’s - scientific importance, operationalised through its 3 work packages and associated scholarly impact and dissemination activities, lies in its original contribution as the first multi-disciplinary study to view MEAs through the lens of the Anthropocene - and its associated constructs. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - GLEC-LAW - - - H2020-MSCA-IF-2016 - - - 751782 - - - - - INSTITUT CURIE - - - EUR 185 076 - - - A biophysical model for ESCRT-III mediated membrane scission - - - EUR 185 076 - - - France - - - Research Organisations - - My project focuses on the characterization of the mechanism of action of ESCRT-III complex. ESCRTs are evolutionary conserved proteins which mediate membrane remodeling and scission in a variety of important cellular - processes, and are implicated in the pathogenesis of many diseases, including virus release and nuclear membrane repair during cancer cell migration. Despite intense research, many outstanding questions still remain unanswered, and all model proposed - remain highly speculative. Based on our preliminary data, we propose a novel, unifying model for ESCRT-III function. The aim of the project is to provide solid data to support this model by an in vitro reconstitution approach, which would constitute - a major contribution in the field. - - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - ESCRT model - - - H2020-MSCA-IF-2016 - - - 751715 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 185 076 - - - Mechanisms of sarcomeric protein homeostasis during physical exercise and ageing - - - EUR 185 076 - - - France - - - Research Organisations - - During ageing muscle fibers are constantly subjected to high forces resulting in mechanical stress on cells and proteins. As a consequence they can degenerate, leading to suboptimal force generation, lack of coordinated - movements and ultimately to muscle failure in the elderly population. This ageing process that leads to a progressive loss of muscle function has a major health impact on the ageing Western society. Physical activity is known to delay this decline. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - REBUILD - - - H2020-MSCA-IF-2016 - - - 751236 - - - - - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - - - EUR 175 419,60 - - - An elastocapillary-enabled self-tunable microfluidic chip - - - EUR 175 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - I am a French citizen with international training in Soft Matter, a growing field that combines Physics, Chemistry and Mechanics. My publications include high-impact factors journals and attract media attention. I am applying - to MSCA fellowships to work with Prof. Gallaire and his group at EPFL, Lausanne, Switzerland. - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - El_CapiTun - - - H2020-MSCA-IF-2016 - - - 750802 - - - - - UNIVERSITY OF LEEDS - - - EUR 97 727,40 - - - Realizing the political rights of persons with disabilities - - - EUR 97 727,40 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Taking as its point of departure the adoption of the UN Convention on the rights of persons with disabilities the fellowship – Realizing the political rights of persons with disabilities (PODI) – examines under which - conditions disabled people’s organisations are most likely to achieve voice and influence on decision-making processes of importance for their own lives and for society as a whole. The United Nations Convention on the Rights of Persons with - Disabilities requires state parties, and the EU, to ‘closely consult with and actively involve persons with disabilities’, notably ‘through their representative organizations’. Enhancement of opportunities for disabled people’s organisations to fully - participate in policy process will assist the EU in furthering its wider ambitions to engage civil society, and to fulfil its international treaty obligations to the UN on disability rights. The fellowship –will produce new knowledge to help make - this a reality. It will launch the first cross-national and multilevel study of disability movements in Europe, beginning with in-depth data from four European countries (Germany, Italy, Norway and UK), and from EU and UN institutions. PODI will - collect and analyse data on individual and organisational level as well as at national, EU and international level. PODI will identify implementation facilitators and barriers and make proposals for indicators to aid the EU and the Member States in - monitoring their fulfilment of the UNCRPD (Articles 4.3, 29 & 33). A European centre of excellence (the Centre for Disability Studies at the University of Leeds, UK) will collaborate with an experienced researcher (Dr Rune Halvorsen, Norway) and - civil society organisations of persons with disabilities (via the European Disability Forum) for intersectoral knowledge transfer, career development, and European added value. - - 2018-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - PODI - - - H2020-MSCA-IF-2016 - - - 749519 - - - - - UNIVERSIDAD DE NAVARRA - - - EUR 170 121,60 - - - Locked between formulas: creativity in oral and transitional poetic texts - - - EUR 170 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - The human mind is capable of creativity and innovation unparalleled by any other species. At the same time, human beings elaborate and preserve complex and highly-stable traditions, transmitting them over very long time spans - by means of the spoken word and through a variety of technologies, such as writing. How does human cognition give rise to such complex manifestations as oral poetic performance, and how are they affected by the introduction of writing? ORFORCREA - investigates the cognitive basis of creativity in verbal art, examining its interplay with both oral tradition and literacy. - - 2019-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - ORFORCREA - - - H2020-MSCA-IF-2016 - - - 749952 - - - - - THE BABRAHAM INSTITUTE - - - EUR 195 454,80 - - - DNA Methylation dynamics during Gastrulation - - - EUR 195 454,80 - - - United Kingdom - - - Research Organisations - - A fundamental aspect of biology is the understanding of how cell fates are established and maintained. Although it is widely accepted that epigenetic reprogramming is a central process of mammalian development, one of the most - intriguing questions that remains unanswered is how DNA methylation marks contribute to cell differentiation and lineage commitment. By combining, novel single cell genomics techniques, CRISPR/dCas9 technology and innovative analytical approaches, - this project will uncover the links between DNA methylation, gene expression and cell fate decisions during mouse gastrulation. This information will be used in a novel way to identify methylation signatures responsible for the stable repression of - pluripotency, which has great potential to advance the development of safe iPS cells. Furthermore, this proposal will implement two innovative approaches utilising single cell DNA methylation patterns to reconstruct lineage trajectories of individual - cells. This project capitalises on the unique combination of my novel analytical approaches, my background in DNA methylation analysis and evolutionary biology together with the extensive expertise in single cell techniques and developmental biology - of the host lab. This multidisciplinary proposal will provide critical insights into how information is encoded in the epigenome and what this information can tell us about a cell’s history within a developing organism. These results will - significantly advance the field of epigenetics, developmental and stem cell biology. Finally, the knowledge and skills gained from this project combined with my scientific and personal development will hopefully open up exciting career possibilities - with the long-term goal to establish my own research group in Europe. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - MeGa - - - H2020-MSCA-IF-2016 - - - 751439 - - - - - INSTITUT CURIE - - - EUR 264 668,40 - - - Discovery and validation of ‘epidrivers’ of cancer evolution and resistance to therapy - - - EUR 264 668,40 - - - France - - - Research Organisations - - Intra-tumoral heterogeneity allows all form of cancers to undergo an evolutionary process in response to selective pressures, such as therapy, which results in a more aggressive disease. As chronic lymphocytic leukemia (CLL) - are particularly amenable to evolutionary investigations, it has been shown that CLL’s capacity to escape therapy is linked in to genetic evolution, which is fueled by intra-tumoral heterogeneity. Aberrant DNA methylation can also dysregulates genes - involved in CLL pathogenesis. Like genetic alterations, DNA methylation modifications are heritable and subject to natural selection. Landau et al have studied sub-population DNA methylation heterogeneity in CLL and uncovered a large amount of - stochastic variation. The acquisition of stochastic DNA methylation alterations enhances epigenetic plasticity and creates a non–genetically encoded source of heterogeneity, fuelling tumour cells in their search for superior evolutionary - trajectories. These new data modify the way we understand cancer epigenetics, and offer a new field of investigation: identify “epidrivers”, i.e. somatic epigenetic alterations leading to cancer-heterogeneity and which are positively selected through - cancer evolution. - - - 2021-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - France - - - METCLL - - - H2020-MSCA-IF-2016 - - - 750345 - - - - - AARHUS UNIVERSITET - - - EUR 200 194,80 - - - A cross-country comparison of Communications designed to Prevent Radicalisation - - - EUR 200 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - The CPR project (A cross-country comparison of Communications designed to Prevent Radicalisation) analyses communications in the UK and Denmark that are designed to contribute to the prevention of vulnerable individuals being - radicalised by terrorist groups such as ISIL. CPR will make a significant contribution to a problem facing many European states – namely how to effectively utilise strategic communications to counter terrorist propaganda. It is widely recognised in - the literature that, to date, Western states have not been sufficiently effective in their counter-radicalisation communication strategies. It is unclear what a more prioritised communicative approach will mean in practice and communication efforts - lack coordination between and, often, within countries to date. By employing an interdisciplinary theoretical approach and utilising unique access to new primary data in both states, CPR will, across four specific research strands, make three major - contributions: i) generate a deeper and more nuanced empirical and conceptual understanding of the effectiveness of current counter-terrorism communications targeted at a range of audiences, ii) provide an empirically unique analysis of the - challenges to effective prevention communications and, iii) provide empirically substantiated and theoretically informed communications-focused policy requirements that will improve the ability of practitioners and policy-makers to design and deliver - communications that contribute to the prevention of radicalisation. CPR will employ a mixed methods methodology, incorporating semi-structured interviews for qualitative analysis alongside online surveys experiments to identify key quantative - insights derived from new primary data. The project multi-actor and multi-level analysis in CPR moves beyond the state of the art in terms of methods and theory, access to data, and addressing new and broader questions in an under explored, and - empirically lacking, area of research. - - 2019-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - CPR - - - H2020-MSCA-IF-2016 - - - 750348 - - - - - UNIVERSITA DEGLI STUDI DI TORINO - - - EUR 176 203,80 - - - Patterns of diffusion and social implications of Massive Open Online Courses (MOOCs): A comparative study between United States and Europe - - - EUR 176 203,80 - - - Italy - - - Higher or Secondary Education Establishments - - The MOOC_DaSI project aims to develop a comparative study between the United States and Europe investigating patterns of diffusion of Massive Open Online Courses (MOOCs) and their contribution to a “smart ad inclusive growth” - through: a) broadening access to education and b) providing individuals with better skills. MOOCs have been pointed out as a flexible, customized, cost-effective type of education that may play a key role in the future of higher education. However, - the outburst of MOOCs also brought about contrasting arguments and so far empirical research is limited and fragmented. The project will contribute to shed light on this topic investigating two main research questions. The first deals with the - organizational aspects of MOOCs diffusion and will explore whether a “European way” to MOOCs can be identified. The second investigates whether MOOCs do contribute in reducing social inequality by a) broadening access to higher education to - non-traditional and socio-economically disadvantaged students; b) providing returns on the labour market. Finally, the research project will summarize a series of policy recommendations providing policy-makers with empirical ground for designing - effective policies in the context of open educational resources. MOOC_DaSI will adopt an interdisciplinary approach spanning between organizational studies, sociology of education and stratification research. The project will also make use of mixed - methods of research, combining qualitative and quantitative data and different methods of analysis. The MOOC_DaSI project will be carried out at the University of Turin (IT) and Stanford University (USA) over a period of 24 months, including a - secondment period at the EC-JRC in Seville (ES). The implementation of the project will contribute to enhance the fellow’s expertise and thus the chances to reach her career objectives of establishing an own research group and obtaining future grants - for large international projects. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Italy - - - MOOC_DaSI - - - H2020-MSCA-IF-2016 - - - 750242 - - - - - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - - - EUR 175 419,60 - - - Heat Transport and its Effects on the Performance of Nanostructured, Photonic Materials - - - EUR 175 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - The PhotoHeatEffect project aims to create a breakthrough in our understanding and ability to control heat transport and exciton-phonon coupling in nanophotonic structures. Both phenomena generate detrimental effects like - local heating and charge carrier escape in current generations of light emitters. Bridging phononics and photonics will reveal the physics behind such device limitations, hence allowing to develop countermeasures leading to better phononic and - photonic designs. Tailoring the heat flow and the coupling between the phonon bath and excitons in nanophotonic structures has strong potential for numerous applications with a wide scope comprising life sciences, optogenetics, electronics, and data - transmission. The project will not only boost the European competitiveness in the fields of thermal transport and phononics, both still dominated by US scientists, but even strives to pioneer a unique linkage to photonics. By employing nitride - materials - a key research asset in the EU and at the host institute - it will be possible to encompass a wide range of emitters that already affect our everyday life (Nobel Prize in Physics 2014). Such polar nitrides are an ideal choice as they are - relevant for classical (light-emitting diodes) and non-classical light sources (few-photon emitters, nano-, and polariton-lasers), which are both suffering from the phononic properties dictated by the material system. The project will resolve this - relation by manipulating the phononic dispersion relation and the excitonic dipole moment independently by a phononic crystal comprising by design tunable electric fields. An analysis of these manipulations will be achieved by combining two-laser - Raman thermometry and µ-photoluminescence spectroscopy. While the latter technique and an analysis of the exciton-phonon coupling match the expertise at hand, the progression towards thermometry and phononics will boost the applicant’s track record - supported by a unique network of partners. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - PhotoHeatEffect - - - H2020-MSCA-IF-2016 - - - 749565 - - - - - UNIVERSITY OF LEEDS - - - EUR 183 454,80 - - - How does dopamine link QMP with reproductive repression to mediate colony harmony and productivity in the honeybee? - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Insects pollinate 80% of crop plants in Europe and pollination services contribute €22 billion to the European economy annually. The honeybee (Apis mellifera) is the most extensively managed pollinator species, yet populations - are declining. Understanding the biology of the honeybee and and factors contributing to its decline is critical for food security and maintenance of biodiversity. - - - 2020-02-29, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - DRiveR - - - H2020-MSCA-IF-2016 - - - 752656 - - - - - EIDGENOESSISCHE FORSCHUNGSANSTALT WSL - - - EUR 187 419,60 - - - The Role of extreme drought and legacy EFfects of long-term manipulatiOn of water availability on growth and REproduction of ScoTs pine REFOREST - - - EUR 187 419,60 - - - Switzerland - - - Research Organisations - - Drought has been identified as an important driving factor for forest decline, hence the long-term tree-level growth assessment in relation to drought events is necessary to understanding resistance and resilience of forests. - In addition, the seedling physiological responses (photosynthesis and respiration) to varying growing conditions are key to forecast the future composition of temperate forests in Europe. Younger stages of a tree’s life cycle are more sensitive to - climate variations than the adult stage. Recent studies demonstrate the important role of transgenerational epigenetic effects for the adaptive capacity of a tree. Although the epigenetic control of gene expression during drought has been shown in - trees at the molecular level, little is known at the physiological level. In this context, the overall objectives of this study are to quantify radial growth of Scots pine and oak along a latitudinal gradient from southern France to northern Germany - with particular focus on the effects of extreme events, and to quantify the potential role of epigenetic effects on seed germination, seedling establishment and survival in variable growing conditions (temperature, light and water). The objective-1 - will be based on annually resolved tree-ring data covering the entire gradient. The distinct role of epigenetic changes on seedling growth and survival (objective-2) will be accomplished applying transplanting experiments with seed from long-term - irrigated trees (13 years) and trees growing under natural dry conditions, in the field and in the laboratories of WSL, Switzerland. The project will explore the adaptive strategies used by Scots pine trees to drought events, which will strengthen - our understanding on the complex relations among climate and ecophysiological mechanisms, essentially benefiting the development of sustainable forest management strategies under climate change in Europe. - - 2019-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - REFOREST - - - H2020-MSCA-IF-2016 - - - 749051 - - - - - UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6 - - - EUR 173 076 - - - Hybrid Entanglement of Light for Interconnected Optical Networks - - - EUR 173 076 - - - France - - - Higher or Secondary Education Establishments - - In quantum information science and technology, two main encodings of information are traditionally used: a ‘discrete-variable’ (DV) approach, based for instance on single photons, and a ‘continuous-variable’ (CV) one, which - relies on continuous degrees of freedom such as amplitude and phase of a light field. A mostly unexplored area combines these two different approaches to create ‘optical hybrid schemes’. Recently, entanglement between particle-like and wave-like - optical qubits, i.e. CV-DV entanglement, has been generated for the first time by the host group. This resource holds the promise of heterogeneous quantum networks where the two encodings can be combined or interconverted. In this context, the - proposed research activities aim at investigating, harnessing, and using the potential of this yet unexplored photonic resource. - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - HELIOS - - - H2020-MSCA-IF-2016 - - - 749213 - - - - - THE QUEEN'S UNIVERSITY OF BELFAST - - - EUR 195 454,80 - - - Predictive modelling of GPCR druggable allosteric sites - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - G protein coupled-receptors (GPCRs) are the most successful class of druggable targets in the human genome with an estimated 30 to 60 % of prescription drugs in European Union. GPCRs biological state can be modulated by small - molecule ligands acting on spatially distinct allosteric binding sites (ABSs) that result more selective and less toxic than drugs binding to orthosteric sites. The discovery of lead compounds targeting ABSs is challenging and to date has largely - been achieved through cost-intensive and time-consuming high-throughput screening. The recent release of X-ray structures of GPCRs in the complex with allosteric modulators opens new opportunities to develop structure-based computer aided - methodologies to identify ABSs. - - 2019-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - United Kingdom - - - MIDAS - - - H2020-MSCA-IF-2016 - - - 748830 - - - - - UNIVERSITE PAUL SABATIER TOULOUSE III - - - EUR 173 076 - - - Exploring LIfestyle Transitions: a molecular and physical anthropology approach of ancient Yakut people - - - EUR 173 076 - - - France - - - Higher or Secondary Education Establishments - - Adaptation, whereby organisms become fitted to their environment, is a key evolutionary process driving biodiversity. Our understanding of how natural selection impacts genetic diversity has greatly advanced with recent - developments in high-throughput DNA sequencing and genome-wide selection scans. However, microbiomes and epigenomes are other systems selection can act upon as they influence our health and phenotype, and thus our fitness. Although microbiomes, - epigenomes and genomes can now be reconstructed, no study has evaluated their relative importance in populations exposed to new selective pressures. This is what ELITE aims at achieving by reconstructing the history of the biological changes - undergone by the Yakut people of Far Eastern Siberia after their contact with Russians in the 17th century, and the resulting profound lifestyle transition, diet shifts and massive epidemiological outbreaks. By applying a multidisciplinary approach - combining the latest advances in physical anthropology, ancient genomics, metagenomics and epigenomics to a unique collection of cultural and biological material from ancient Yakuts, ELITE proposes an innovative experimental approach in evolutionary - biology, which could eventually reveal a possible maladaptation to our modern lifestyle, making us more susceptible to diseases. The success of ELITE will be based on the excellent synergy between the experienced researcher and the host institution, - as the applicant will benefit from state-of-the-art facilities and expertise to gain advanced training in physical anthropology methods, while applying her genomic skills to a sample set available at no other research institution in the world. By - acquiring these new skills in an international context, the experienced researcher will become a fully trained evolutionary anthropo-genomicist at the interface of physical and molecular anthropology, which will place her in ideal conditions to - develop as a mature and independent researcher. - - 2019-09-03, ongoing project - - - 2017-09-04 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - ELITE - - - H2020-MSCA-IF-2016 - - - 748122 - - - - - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - - - EUR 175 419,60 - - - High Performance Wide Bandgap and Stable Perovskite-on-Silicon Tandem Solar Cells - - - EUR 175 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - The world is moving toward a low-carbon future. The EU Commission’s 2015 Paris climate agreement vowed to keep global average temperature to well below 2°C above pre-industrial levels and undertake rapid global emission - reductions. Generation of clean energy such as photovoltaics is one of the most promising solutions. Novel organic-inorganic perovskite materials for solar cells have drawn vigorous scientific interest over the past few years due to their potential - low cost, high charge carrier mobility, absorption coefficient and efficiency. The two top scientific journals, Nature and Science, selected perovskites as one of the biggest scientific breakthroughs in 2013. As perovskites are still in the early - development stages, barriers need to be overcome before they can be commercialized. This interdisciplinary project draws from chemistry, physics and engineering with the aim of developing stable high bandgap mixed-cation/halide perovskite devices. - Both photo- and moisture stability will be carefully studied and improved upon leading to the ultimate goal of fabricating a stable monolithic perovskite/silicon tandem solar cell with an efficiency >30%. Monolithic perovskite/silicon tandem - technology has the potential to revolutionize the photovoltaics industry by greatly decreasing cost through improved efficiency making clean energy more competitive against fossil fuels. The project will be conducted at EPFL PV-Lab, a dedicated - photovoltaic research centre with over 30 years of experience and close links with Swiss and European research institutes and industries. EPFL is a highly-ranked European engineering institution with world-class facilities, industrial connections and - technological parks. The fellow Dr. Terry Chien-Jen Yang will be joining PV-Lab to bring unique nano-material and analytical expertise as well as collaborations from the prestigious School of Photovoltaic and Renewable Energy Engineering, UNSW in - Sydney, Australia. - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - POSITS - - - H2020-MSCA-IF-2016 - - - 747221 - - - - - UNIVERSITEIT VAN AMSTERDAM - - - EUR 165 598,80 - - - The Constitutional Place of Expertise - - - EUR 165 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - The project explores how constitutional principles can enhance the democratic legitimacy of expert-based decision-making in the European Union (EU). It does so by focusing on participation, transparency and administrative - rationality, as interpreted by European Courts when reviewing expert-based decisions, and as incorporated into institutional practices involving both scientific and economic expertise. In particular, CONPLEX aims at detecting links and influences - between Courts’ activity and decision-making processes, capable of leading to a deeper integration of expertise within the constitutional discourse. The proposal draws on a new legal realist approach to legal research, and combines doctrinal analysis - of the Courts’ case-law and empirical investigation of institutional practices – through documentary analysis and semi-structured interviews to Commission’s officials and experts. The project is original from a conceptual, methodological and - empirical perspective and makes a timely contribution to the on-going debate on technocracy and democracy in the EU, especially with regard to the role played by scientific and economic experts in politically controversial issues. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - CONPLEX - - - H2020-MSCA-IF-2016 - - - 748463 - - - - - EOTVOS LORAND TUDOMANYEGYETEM - - - EUR 134 239,20 - - - Extremal Sparse Graphs and Graph Limits - - - EUR 134 239,20 - - - Hungary - - - Higher or Secondary Education Establishments - - This proposal focuses on two related families of problems concerning algebraic invariants of graphs, i.e., networks. On the one hand, we study extremal values of algebraic invariants, i. e., we propose to give lower and upper - bounds for certain algebraic graph parameters in a given class of graphs like d{regular graphs. On the other hand, we study the behavior of algebraic invariants of very large graphs, more precisely we study whether for a certain graph parameter p(G) - it is true that the sequence (p(G_n)) converges if the graph sequence (G_n) converges in some sense. The two families of problems are connected by the observation that many graph parameter does not achieve its extremal value on finite graphs, but on - some infinite object which is the limit of finite graphs. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Hungary - - - ExtSpGraphLim - - - H2020-MSCA-IF-2016 - - - 747430 - - - - - FUNDACION PARA LA INVESTIGACION MEDICA APLICADA FIMA - - - EUR 158 121,60 - - - Advancing cancer immunotherapy using natural killer cells for hematological and metastatic cancers - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - The development of monoclonal antibodies (mAb) to target tumor cells has tremendously improve cancer immunotherapy and benefit the treatment of aggressive cancer such as some types of lymphomas, leukemias, multiple myeloma and - metastatic cancers. One of the mechanisms of action is the induction of antibody-dependent cellular cytotoxicty (ADCC) through the activation of CD16 on NK cells after binding to the Fc portion of Ab-coated tumor cells. Therefore, strategies that - combine NK cell activation and mAb therapy has been intensively explored. However, tumor heterogeneity and unstable expression of the targeted molecule in the tumor cells limits ADCC for mAb therapy resulting in cancer relapse. Furthermore, intrinsic - NK immunregulatory mechanisms as well as NK-specific tumor evasion mechanisms have also negatively impacted the use of NK cell-based therapies. In this proposal we will explore the mechanisms involved in the reduced NK cell function (NCF) observed - after ADCC and/or NK cell activation (NCA) in order to develop novel strategies to achieve a sustained and stronger NCF by combining stimulating signals with suppression of inhibitory signals such as costimulation via CD137 and IL12, or SHP1/2 - blockade. We hypothesize that the adoptive transfer (AT) of NK cells expanded by this novel method will result in better anti-tumor responses after mAb therapy even in tumor cells that express limited amount of the target molecule and limiting - consequently cancer relapse rates. Furthermore, due to the overall improvement on NCF, we expect that the combination of AT NK cells with hematopoietic stem cell transplantation (HSCT) will also increase anti-tumor responses; which efficacy up to - date has shown to be rather limited. Given the versatility of our approach, this therapy can be used for the treatment of many cancers, but particularly hematological and metastatic cancers and potentially can be translated into the clinic in a short - time frame. - - 2020-02-14, Grant Agreement signed - - - 2018-02-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - CINK - - - H2020-MSCA-IF-2016 - - - 746985 - - - - - NATURAL HISTORY MUSEUM - - - EUR 183 454,80 - - - Systematic Characterisation and Archiving of megafauNa on a regional scale in a Deep-sea area threatened by mining - - - EUR 183 454,80 - - - United Kingdom - - - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - The worldwide demand for metals and rare-earth elements is increasing, fuelled by developing economies and the growth of high-technology green industries. The Clarion-Clipperton Zone (CCZ) in the tropical eastern Pacific Ocean - contains vast reserves of polymetallic nodules on the abyssal seafloor, a future source of deep-sea minerals already targeted for exploitation. There is an almost complete absence of open biodiversity data on the large animals (megafauna) of this 6 - million km2 area, and it is a pressing conservation priority to establish baseline data to enable future sustainable management of the region. In particular, a regional-level assessment that cuts across contracted areas is urgently needed to [1] - establish the baseline quantitative ecology of the region, [2] assess species richness and ranges and thus, [3] enable the successful management of this globally important marine area in the context of a global ‘blue growth’ agenda. The objective of - this fellowship is to develop the first regional-level approach to megafauna classification and identification in the CCZ. This will be done using a three-fold approach: (1) The development of a new open-access data-archiving bioinformatic pipeline - for imagery and samples of megafauna from the entire CCZ, (2) the identification and characterization of megafaunal morphotypes observed across the CCZ regardless of exploration contract area and (3), development of biodiversity survey methods based - on organismal DNA found in the environment (metabarcoding). This project will include knowledge transfers between the host and experienced researcher in the following areas: bioinformatics, digitisation, image analysis, megafauna taxonomy, DNA - barcoding, metagenomics and transferable skills such as project management, scientific communication including science-policy interface work, laboratory health and safety, and career planning. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SCAN-Deep - - - H2020-MSCA-IF-2016 - - - 747946 - - - - - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - - - EUR 187 419,60 - - - Deformable vascular registration for co-mapping altered hemodynamics with vascular responses,and for introducing a new measure for aneurysm rupture risk assessment: the local surfacegrowth - - - EUR 187 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - Growth rate of ascending aortic aneurysm (AsAA) is a rupture risk marker as it potentially reflects a wall remodeling that leads to fast growth. It is measured as the maximum diameter change over time. However, expansion is - not uniform but presents localized growth. We propose to develop a methodology based on deformable surface registration tools that will provide correspondence between aortic surface meshes obtained at consecutive time points and quantify vascular - surface growth distribution. The direct application of this methodology in animal and clinical research will answer some long debated questions about AsAA pathology. While a cause and effect relationship between hemodynamics and lesion development is - long suspected, exact quantification of the responsible hemodynamic factors has not been performed so far. This is because the geometry changes between baseline (measurement of initiating hemodynamics with computational fluid mechanics) and end stage - (lesion development), making it difficult to identify corresponding regions at the microscopic level of lesion size. We will use angiotensin II-infused ApoE-/- mice, a model for AsAA, and apply the developed registration methodology to obtain a - detailed correspondence between the 3D images, and co-map the complex initiating hemodynamic microenvironment and the histological findings at sacrifice for the identification of disturbed hemodynamics. Furthermore, the local wall expansion can - indirectly provide information about aneurysm state. We will associate maximum local growth with the degree of aneurysm initiation (size of media tear) which will be used as a groundwork and pre-clinical justification to introduce the regional growth - measurement in clinical risk assessment. Lastly, clinical data from AsAA patients will be used in order to correlate the maximum regional growth with clinical outcome, which will establish a new metric for a more sensitive aneurysm growth - quantification. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - VASCFORM - - - H2020-MSCA-IF-2016 - - - 747094 - - - - - UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6 - - - EUR 264 668,40 - - - CArbon Production of under-ICE phytoplankton blooms in a changing Arctic Ocean - - - EUR 264 668,40 - - - France - - - Higher or Secondary Education Establishments - - Over the last decades, sea-ice in the Arctic Ocean (AO) has undergone unprecedented changes, with drastic decline in its extent, thickness and duration. Modern climate models are unable to simulate these changes, leading to - large uncertainties in Arctic and Global Change predictions. Sea-ice strongly attenuates solar radiation and it is generally thought that phytoplankton, which drives Arctic marine CO2 sequestration, only grow in open waters once sea-ice retreats in - spring. However, the discovery of large under-ice phytoplankton blooms (UIBs) growing beneath sea-ice contradicts this paradigm. UIB productivity in ice-covered regions has been suggested to be ten-fold larger than presently modeled. By initiating an - international network (USA, France, Canada, Germany, Norway), the CAP-ICE project will acquire knowledge on the occurrence of UIBs, the physical mechanisms that control their initiation and productivity, and will quantify how UIBs affect the Arctic - carbon cycle and climate. - - 2021-01-14, ongoing project - - - 2018-01-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - France - - - CAP-ICE - - - H2020-MSCA-IF-2016 - - - 746748 - - - - - UNIVERSITEIT LEIDEN - - - EUR 165 598,80 - - - Deep Investigation on Molecular Processes At early Cosmic Times - - - EUR 165 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - The discovery of galaxies formed when the Universe was less than 1 Gyr old has been a major breakthrough of extragalactic astronomy. During this period, called Epoch of Reionization (EoR), the Universe experienced a dramatic - change: from being a dark “sea” of neutral hydrogen and helium, it got completely reionized and polluted with elements heavier than helium. Thus, characterizing the bulk of galaxy population at these early epochs is pivotal because of their strong - impact on the cosmic evolution. - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - DeepIMPACT - - - H2020-MSCA-IF-2016 - - - 746119 - - - - - UNIVERSITE DE STRASBOURG - - - EUR 185 076 - - - Antiferromagnetic spin-chiral triangles as decoherence-free qubits - - - EUR 185 076 - - - France - - - Higher or Secondary Education Establishments - - Quantum Information Processing (QIP) is a groundbreaking new field with implications ranging from overcoming Moore's law to the security of encrypted communications. As such it has been identified as a priority by the European - Commission. With several theoretical concepts having been clearly defined, and with quantum limits to Moore's law approaching, it is now important to find materials that will allow the physical implementations of qubits, the principal components for - QIP. Molecular Nanomagnets (MNMs) are promising such materials which, however, exhibit short quantum decoherence times. CHIRALQUBIT identifies a new quantum property of MNMs, spin chirality, as a means to overcome this limitation and achieve - decoherence-free qubits, with the added advantage of their rapid and precise electric manipulation. The project’s objectives are to confirm for the first time the electric control of spin-chiral coordination complexes, in particular antiferromagnetic - triangles of half-integer spins, and study their relaxation and decoherence dynamics regarding transitions reversing their spin chiralities. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - France - - - CHIRALQUBIT - - - H2020-MSCA-IF-2016 - - - 746060 - - - - - FUNDACION UNIVERSITARIA SAN PABLO-CEU - - - EUR 170 121,60 - - - An Integrated Computational and Experimental Approach to Rapid Synthesis of Highly Selective Dual-Targeted HDAC/CK2, MMP2/CK2 Inhibitors - - - EUR 170 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - Traditional drug design strategy based on a single target has serious difficulties in developing new therapies for diseases such as cancer. - - 2020-02-29, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - DUALITY - - - H2020-MSCA-IF-2016 - - - 746225 - - - - - ARCELIK A.S. - - - EUR 145 845,60 - - - Development of nano-Photocatalytic Materials for Indoor Air Purification and Odour Elimination - - - EUR 145 845,60 - - - Turkey - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Pollutants released directly to the air are particularly harmful compared to soil and water pollutants. These pollutants severely affect people’s life quality and life expectancy. Indoor air purification at highly populated - urban areas is technically challenging, because indoor air contaminants arise from both outside and indoor sources. The most hazardous indoor pollutants are volatile organic components, toxic inorganics, dust, bacteria, pollen and mold spores. - Conventional ventilation brings outdoor air pollution inside the buildings and thus increases energy consumed for cleaning per room. Adapting new technological advances will help meeting requirements of a compact, reliable, and eco-friendly design. - The main objective of this proposal is therefore to develop the next generation air purifiers where photocatalytic oxidation (PCO) technologies will allow elimination of a variety of hazardous indoor air pollutants, and bad odour caused by such - pollutants, when illuminated by low-power light sources on-the-fly. The proposed project composes of four different phases: the state-of-the-art design of photocatalysts, selection of proper illuminating source, configuration of PCO system, and - preparation of the first prototype. In this study, we will address the limited work performed within the field hitherto, such as the mechanism of catalyst deactivation, efficiencies of odour removal, generation of by-products, electron-hole - recombination phenomenon, and the ways of providing anti-bacterial/good hygiene properties. We will carry out an in-depth investigation on optimization of PCO air purification system within an interdisciplinary work at Arçelik Central R&D. After - designing a viable configuration, we will focus on the production of a PCO air purifier prototype. In accordance with Arçelik Group’s policy and vision, our final goal is to ready the highly energy-efficient, low-noise, and reliable PCO air purifier - prototype for the product launch in the global market. - - 2019-06-04, ongoing project - - - 2017-06-05 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-SE - Society and Enterprise panel - - - Turkey - - - nanoPhotoMat - - - H2020-MSCA-IF-2016 - - - 746094 - - - - - THE QUEEN'S UNIVERSITY OF BELFAST - - - EUR 195 454,80 - - - Protecting Human Rights and Public Health in Global Pandemics: A Map of the Standards Applied by EU and US Courts - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - THEMIS asks: How do judges resolve the conflict between individual human rights and public health caused by global pandemics such as Zika, Ebola and SARS? Building on the researcher’s expertise in both EU law and risk - regulation, and the supervisor’s pioneering ‘risk within rights’ framework, it focuses on EU and US case-law to create the first comparative map of judicial standards in this challenging field. It develops the role of law in pandemic preparedness; a - crucial issue affecting all of us, and meets the aims of the 3rd EU Health Programme. In so doing, THEMIS recognises that lawyers do not act alone, and that the scholarly and the practical have a reciprocal impact. Thus it utilizes a ‘Lawyers meet - Doctors’ dissemination strategy, facilitating inter-disciplinary impact on academic and policy experts. It features two inter-sectoral secondments enabling access to both key EU and global policy-makers (WHO; the Public Health Agency in NI), and - cross-disciplinary knowledge-transfer and networking via international workshops co-run with the host institution’s Centre of Excellence for Public Health (one of five in the UK). The researcher’s home at Queen’s will be the Health & Human Rights - Unit, the first such unit within a top 20 UK law school. Queen’s also enjoys ‘HR Excellence in Research Status’ and boasts a Gender Initiative for women staff and a long-established Human Rights Centre. Each of these supports the skills and training - plan, as do the project’s varied outputs: including a monograph (essential for the researcher’s independent academic position), journal articles, and presentations to both the lay public and policy experts during the secondments. In line with IF - objectives, THEMIS enables the researcher to use international mobility, new networks and training to attain a position of leadership in the scholarly community, and contributes to the need for a better understanding of how to prepare for, and - respond to, the risks of global pandemics. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - THEMIS - - - H2020-MSCA-IF-2016 - - - 746014 - - - - - INSTITUT CURIE - - - EUR 185 076 - - - A quorum sensing mechanism regulating CD4 T cell proliferation - - - EUR 185 076 - - - France - - - Research Organisations - - The fine and complex regulation of CD4 immune response is important in cancer, autoimmune diseases, inflammatory disorders and viral infection. If signals orchestrating productive CD4 T-cell responses are well documented, the - contraction of antigen (Ag)-specific CD4 T-cell populations following the resolution of primary immune response is however not molecularly understood. It has been demonstrated that a negative feedback loop can regulate CD4 T cell proliferation - through direct T-T interactions, leading to the preferential exclusion of Ag-experienced T cells. This T cell intrinsic mechanism limits the expansion of effector CD4 T cells and may then interfere with therapeutic vaccine efficacy. Using - Cas9-(constitutive/inducible)-expressing Dby-reactive T cells (from a TCR Transgenic RAG-/- mouse strain named Marilyn) coupled to a sgRNA library and an in vivo selection strategy, we will extensively identify the negative regulators of CD4 T cells - migration and priming in an ongoing primary immune response. As a proof of concept, we will first inactivate candidate genes (already known to be involved in CD4 T cells negative regulation: TGF-b receptor,IFN-γ receptor, PD-1 and PD-L1) in - Ag-experienced memory CD4 T cells, which will be enriched for their proliferative capacity in vivo and used as a second cohort in immunized mice. Then, we will develop a genome-wide screen approach to generate a library of knockout Ag-experienced T - cells as a second cohort. We expect that further insight into CD4 suppressive mechanisms, which dampen efficient antitumor immune responses, will allow optimization of cancer immunotherapy. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - CD4CRISPR - - - H2020-MSCA-IF-2016 - - - 743435 - - - - - UNIVERSITY COLLEGE LONDON - - - EUR 195 454,80 - - - Phosphate homeostasis and energy metabolism in Dictyostelium discoideum - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Adenosine triphosphate (ATP) is the universal biological energy currency. Its cellular concentration is tightly regulated and depends on rates of glycolysis, oxidative phosphorylation, and obviously on phosphate availability. - How is phosphate concentration regulated as a function of the cell’s demands? Inositol pyrophosphates, described as metabolic messengers, are excellent candidates to orchestrate phosphate homeostasis and energy metabolism. The research programme - proposed here aims to elucidate the relationships between phosphate homeostasis, energy metabolism, and inositol pyrophosphates using the amoeba Dictyostelium discoideum as a model system. This organism has high levels of inositol pyrophosphates and - inorganic polyphosphate (polyP) and, surprisingly, a comparatively low level of ATP, suggesting that inositol pyrophosphates may serve as a phosphate reservoir for ATP production. I will use a combination of metabolomics analysis, steady-state and - dynamic flux analysis of ATP, polyP, Pi and inositol pyrophosphate levels, and a functional analysis of mitochondria to evaluate the impact of polyP and inositol pyrophosphates on the metabolic/energetic state of this organism. I will investigate the - function of polyP, which is induced during development, to understand how and why phosphate homeostasis is so dramatically modified during this process. This will be the first comprehensive analysis of the relationships between phosphate homeostasis - and energy metabolism in eukaryotes. - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - PHEMDD - - - H2020-MSCA-IF-2016 - - - 752903 - - - - - TECHNISCHE UNIVERSITAET MUENCHEN - - - EUR 159 460,80 - - - Robotic self/other distinction for interaction under uncertainty - - - EUR 159 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - There will be around 35 million private or non-industrial use robots in the world by 2018, a market of 19 billion euros. However, autonomous robot technology in Europe is not yet ready to lead this high expectancy due to the - lack of robust functionality in uncertain environments. Particularly, safe interaction is an essential requirement. A basic skill, still unachieved, is to allow the robot to be aware of its own body and perceive other agents. Recent evidence suggests - that self/other distinction will be a major breakthrough for improving interaction and might be the connection between low-level sensorimotor abilities and conceptual interpretation. - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - SELFCEPTION - - - H2020-MSCA-IF-2016 - - - 741941 - - - - - ISTANBUL TEKNIK UNIVERSITESI - - - EUR 157 845,60 - - - Developing Stretchable Conductive Fibres and their Implementations in Wearable Electronics - - - EUR 157 845,60 - - - Turkey - - - Higher or Secondary Education Establishments - - Europe needs to take action to develop stretchable conductive materials to lead to the wearable electronics industry, which will be worth over $30 billion dollars in 2020. Although flexible electronics are dominating the - current wearonics industry, their applications are restricted due to significant reduction in their conductivity under the applied strain. All stretchable conductors with mechanical compliance materials like human skin are required for epidermal - electronic devices and wearable electronics. The ideal solution to this problem would be using a stretchable conductive material that can be woven into washable and breathable fabrics, which remains a significant challenge. To address this challenge, - I have formulated an innovative and interdisciplinary strategy based on my research experience to develop stretchable conductive fibres (SCF) using silver nanowires and spandex fibre. After developing SCFs, I will bring together diverse academic and - industrial experts to utilize SCFs in 4 different research environments. First, I will receive intensive training at the Wireless Communication and Research Lab to utilize SCFs in wireless communication and pervasive computing systems. Then, I will - integrate these systems into the disabled friendly apparels at Universal Textile Centre. Finally, I will be seconded to two industrial organisations, ComfTech and Antelope, to create SCF based prototypes of Health Monitoring Systems and Electro - Muscle Stimulation technologies. This fellowship will allow me to gain new expertise in multiple disciplines, and build complementary international partnerships between academia and industry, which will enable me to enhance my independence as a - researcher in the wearonics field. The successful completion of this timely and innovative project will result in an advanced material that will contribute to the competitiveness of Europe in the wearonics field. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Turkey - - - Wearonics - - - H2020-MSCA-IF-2016 - - - 739891 - - - - - ELVESYS SAS - - - EUR 185 076 - - - Multi-compartmental Organ-on-a-Chip - - - EUR 185 076 - - - France - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Drug development is stuck in an innovation gap, in which it incurs staggering expenses and takes many, ten to fifteen, years to get a drug to market, furthermore, during the process many animals are sacrificed in preclinical - work, and in the end many times the results from the animal studies does not accurately predict what will happen in humans, resulting in failures, delays, and recalled drugs. There is currently a gap in the preclinical testing platform for - therapeutics. Organ-on-a-chip technologies of closing this gap, and have the potential of curtailing the high experimental costs and complexities associated with in vivo studies, and eventually evolving into next generation tools for therapeutic - validation and development. - - - 2020-03-15, Grant Agreement signed - - - 2018-03-16 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-SE - Society and Enterprise panel - - - France - - - MOOAC - - - H2020-MSCA-IF-2016 - - - 753743 - - - - - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - - - EUR 183 454,80 - - - Adapting to Change: Experimental Evolution of Environmental Sensing Systems in Bacteria - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Background: Coping with ever-changing conditions is a problem common to most living things. One solution that organisms have come up with is the evolution of systems that allow them to sense and respond to their surroundings. - Despite being usually complex and costly to maintain, sensing devices are widespread throughout the Tree of Life, which has puzzled researchers for years. Theory has identified a number of scenarios that promote the emergence of environmental sensing - systems. Yet, most aspects of their origin and evolution remain obscure; largely due to the practical difficulties of observing these processes in real time. Here I propose to fill this gap by combining experimental evolution with the Host Group's - expertise on the molecular regulation of bacterial behaviour. Methodology: The plan is to couple sudden changes in growth conditions with arbitrary environmental cues (e.g., toxic metals) to select for bacteria capable of reading these cues and - altering their behaviour accordingly. I will target a well-studied behaviour: motility, which plays a key role in nature allowing bacteria to find good conditions and move away from threats. Using this setting, I will test decades-long hypotheses - about the genetic and ecological factors that shape the emergence of novel sensing systems. Later, I will exploit the power of new DNA sequencing techniques to work out how genetic changes drive the new behaviours. Impact: This research will shed - light on how readily novel sensing systems can evolve, thus contributing to efforts to understand pressing issues such as the emergence of multi-drug resistance pathogens or the response of natural populations to the current global change. Outcomes - could also help in the design of novel antimicrobial drugs and microbe-based reporters with applications in bioremediation (e.g., detection of contaminants), biotechnology (e.g. monitoring of industrial processes) and in Public Health (e.g., - detection of pathogens in water supplies). - - 2019-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ESSEVOL - - - H2020-MSCA-IF-2016 - - - 750129 - - - - - KING'S COLLEGE LONDON - - - EUR 183 454,80 - - - Ebola virus manipulation of the cellular stress responses - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Ebola virus (EBOV) is a highly pathogenic filovirus that causes severe haemorraghic fever and killed over 11,000 people during the recent epidemic in Western Africa. Although potential vaccines and drugs are being tested, no - treatment has been approved. Therefore, understanding the cellular regulation of EBOV replication is fundamental to develop novel treatments. - - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - StressEBOV - - - H2020-MSCA-IF-2016 - - - 750621 - - - - - UNIVERSITAETSMEDIZIN GOETTINGEN - GEORG-AUGUST-UNIVERSITAET GOETTINGEN - STIFTUNG OEFFENTLICHEN RECHTS - - - EUR 171 460,80 - - - TIMING FERTILIY- A Comparative Analysis of Time Constructions and the Social Practice of Egg-Freezing in Germany and Israel - - - EUR 171 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - "Technological advancements in reproductive medicine have introduced the new concept of "FREEZING". Nowadays, healthy women are given the possibility to cryopreserve their oocytes in order to prolong their fertility, a - procedure known as "social egg freezing". There is an ongoing bioethical academic and public debate on the social and ethical implications of this practice. The here proposed socio-empirical research is interested in extending our understanding of - the concept of "freezing" in broader contexts, while analyzing it through the prism of 'sociology of time'. Egg freezing constitutes an extremely fascinating paradigm for studying concepts of time, timing, planning and its social-technological - manipulation related to modern life science. In line with the IF work program's focus on creativity, innovation and diversity, this research aims to examine the interplay of culture and bioethics in an interdisciplinary and empirical manner, focusing - on and comparing experts' and lay positions and using a cross-cultural German-Israeli comparative research framework. This cross-cultural comparison is especially interesting since the German regulatory and legal framework regarding new reproductive - technologies is rather restrictive, while the Israeli regulation has been identified as extremely permissive. Using qualitative in depth interviews with relevant experts as well as users of social egg freeing, this research aims at (a) In-depth - empirical analysis of time in the context of reproductive medicine; (b) A cross sectional analysis of social egg freezing by comparing two national contexts as well as experts and ordinary (lay) ethics; and (c) Theorization of the time dimension for - the relationship of reproduction, labor and gender. Thus, this innovative research is expected to enhance the researcher academic competence and the transfer of new knowledge." - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - TIMEGG - - - H2020-MSCA-IF-2016 - - - 749889 - - - - - UNIVERSITEIT LEIDEN - - - EUR 177 598,80 - - - Advanced graphene nanodevices with functional hydrogels for DNA sequencing - - - EUR 177 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - With this proposal, I propose a new chemical approach inspired by DNA gel electrophoresis to slow down DNA translocation through a graphene nanopore or a nanogap, and to reduce the mechanical fluctuations of the graphene - membrane as DNA translocates. Thus far using graphene nanodevices to sequence DNA molecules in real time has been hampered by two major drawbacks: i) the too fast translocation of single DNA molecules through a graphene nanodevice, and ii) the very - large low frequency electronic noise presumably due to mechanical vibration of the free-standing graphene membrane in aqueous buffers. Both these phenomena prevent single nucleotide identification (at least compared to biological nanopores). The - direct chemical functionalization of graphene film with functional polymeric hydrogels will i) induce electrostatic and chemical affinities between DNA and the functional polymer hydrogel and ii) stabilize mechanically graphene from vibrating. The - host group of Dr. Schneider was the first to propose graphene nanopores as single molecule DNA sensors in 2010 and has gained a lot of experience in this field. Dr. Schneider’s group is now approaching DNA sequencing with graphene nanostructures with - a strong chemistry component. Schneider’s lab in Leiden is therefore, at the moment, the best place in the world to make this research proposal a success. I do believe this proposal has the potential to lead toward ground-breaking applications in - nanopore-based biosensors, particularly for high throughput next generation sequencing applications with graphene nanogaps. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - GRAPHNANOGEL - - - H2020-MSCA-IF-2016 - - - 749671 - - - - - UNIVERSITY OF WOLVERHAMPTON - - - EUR 183 454,80 - - - Epistemological Gaps in Cultural Theories of the Soviet East and Democratic West in the 1960s and 1970s - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - In this project the fellow is concerned with opening out the period of Brezhnev’s Thaw in the Soviet Union in the 1960s and 1970s, to a renewed scrutiny. Covering art theory, cultural theory, philosophy, and political - philosophy, the research will draw on both key and forgotten works, such as those by Evald Ilyenkov, Yuri Davidov, Lev Vigotsky, Georg Lukacs and Mikhail Lifshitz, as well as the critical legacy of Moscow conceptual art in order to better understand - the dynamics of Soviet culture and its influence on contemporary culture, politics and art in Europe. This fellowship will challenge the largely negative perception of the cultural and philosophical achievements of this historical period. By using a - cross-disciplinary approach, the fellow will demonstrate how the Brezhnev period, contrary to received views, produced a rich array of heterodox social theories, critical thinking, and cultural practices, that are comparable to Western emancipatory - thinking and cultural theory of the time, but, remain, in quality, ambition and character, very different to their Western counterparts. The fellowship aims, then, to transform the conventional approach to post-socialist studies within the European - academic context, in order to support and enhance a much needed cultural dialogue between the European Union and Russia. - - 2019-11-06, ongoing project - - - 2017-11-07 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - EGap - - - H2020-MSCA-IF-2016 - - - 752417 - - - - - LINNEUNIVERSITETET - - - EUR 173 857,20 - - - Gender Aspects of Screen Adaptations of the British Nineteenth-Century Female Literary Canon - - - EUR 173 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - The aim of the project is to analyse the gender aspects of British and American screen adaptations of selected nineteenth century women’s novels. As the contemporary popular culture is increasingly reliant on adaptation and - other derivative types of cultural texts such as sequels, retellings, and pastiche, it becomes vital to study the continued appeal of canonical literature. The project aims to study screen adaptations released between 1990 and 2010, which are - internationally known and became parts of the shared collective cultural experience, influencing the popular perception of European nineteenth-century culture and the position of women within that culture. The project will consist of four components: - (1) studying the adaptation authors’ (directors, screen writers etc.) stated motivations and perceptions of the original writers, revealed in interviews, DVD commentaries and other ancillary materials; (2) analysing the nature of “novel to film” - changes, with special attention to the portrayal of female characters and the issues of women’s agency and empowerment; (3) studying the role of the visual elements, e.g. costumes, scenography, cinematography and editing in the portrayal of female - characters (4) analysing the receptions of adaptations and studying the possible “film to novel” transmission. The proposed research project is highly interdisciplinary in nature, aiming to use in a complementary way the perspectives of adaptation - studies, gender studies and reception studies and film studies. It is based on solid theoretical founations (understanding he nature of the transmedial shift), but also involves a case-study approach to the chosen novel-and-adaptations clusters. Its - expected impact is to offer a comprehensive analysis of the issues of women’s agency and empowerment in the selected adaptations and to study the influence of these adaptations on the audiences' perception of the nineteenth-century culture. - - 2019-10-01, ongoing project - - - 2017-10-02 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - GASAC - - - H2020-MSCA-IF-2016 - - - 750690 - - - - - INSTITUT BARCELONA D ESTUDIS INTERNACIONALS, FUNDACIO PRIVADA - - - EUR 170 121,60 - - - Electricity in the Mediterranean: Promoting good regulatory governance - - - EUR 170 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - In the face of rising concerns for energy security and for climate change, huge investment projects about the production of renewable energies in the Southern Mediterranean area are under consideration. Regulatory reform and - good governance of electricity markets, offering a stable and competition-based regulatory regime, are fundamental to inspire the trust of potential investors. However, their authoritarian political culture, political instability and developmental - policies make Southern Mediterranean countries an unfavourable ground to the development of good regulatory governance. - - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - RELMED - - - H2020-MSCA-IF-2016 - - - 748135 - - - - - TARTU ULIKOOL - - - EUR 136 582,80 - - - Patterns and management of ethnic relations in the Western Balkans and the Baltic States - - - EUR 136 582,80 - - - Estonia - - - Higher or Secondary Education Establishments - - ‘Patterns and management of ethnic relations in the Western Balkans and the Baltic States’ - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Estonia - - - MERWBKBS - - - H2020-MSCA-IF-2016 - - - 749400 - - - - - Institut Català de Recerca de l'Aigua, Fundació Privada - - - EUR 170 121,60 - - - Groundwater quality assessment in areas with intensive livestock: is manure recycling a major source of pollution and dissemination of antibiotic resistance genes?” - - - EUR 170 121,60 - - - Spain - - - Research Organisations - - Groundwater protection is one of the latest environmental battlegrounds in Europe. It is used as a major source for drinking water production all over Europe and as such, the preservation of its chemical and microbiological - quality is of vital importance. In agricultural areas with intensive livestock activities, groundwater quality might be seriously compromised by the excessive use of manure as organic fertilizer. Animal manure may contain high levels of organic - contaminants (e.g. antibiotics, nitrogen-containing compounds) and bacteria carrying antibiotic resistance genes (ARGs), and its reuse as soil amendment could be an important route of entry of these pollutants into groundwater bodies. This project - aims at broadening the knowledge about the role of animal manure recycling as a major source of groundwater pollution by: (i) analyzing selected multiple-class antibiotics and ARGs and (ii) using an innovative approach, based on the bulk - characterization of dissolved organic matter (DOM) by high resolution mass spectrometry (HRMS), to uncover the chemical pattern of selected manure-impacted groundwater bodies, used as sources for drinking water production, and provide evidence about - the role of manure recycling as a major source of aquifer pollution. RESOURCE is a project with high societal relevance in Spain. The shutdown of large scale manure treatment plants in 2014 and the subsequent generation of large amounts of untreated - waste might endanger the good chemical and microbiological status of drinking water wells. Thus, the outcomes of this project will be highly valuable to assess the current status of groundwater bodies and will contribute in preventing serious - environmental and human health issues. The fellow’s expertise, gathered in international top research institutions and the outstanding infrastructure and capabilities available at ICRA, makes an ideal conjunction for the successful completion of the - project. - - 2019-10-01, ongoing project - - - 2017-10-02 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - RESOURCE - - - H2020-MSCA-IF-2016 - - - 750104 - - - - - Institut Català de Recerca de l'Aigua, Fundació Privada - - - EUR 158 121,60 - - - Development of a smart workflow based on high resolution mass spectrometry for the assessment of the performance of wastewater treatment technologies - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - Discharges from wastewater treatment plants (WWTPs) are one of the major sources of aquatic pollution. The increased detection of a wide range of organic micropollutants in the aquatic environment shows the limitations of - conventional WWTPs (developed and designed to protect natural aquatic systems and water resources mainly by removing loads of carbon, nitrogen and phosphorous) in removing these compounds. Therefore, advances in WWTP technologies are crucial to limit - the burden of WW-originated contaminants. To date, one of the main challenges is to appropriately evaluate the different treatment technologies regarding their potential to minimize the toxicological risks for biota and human health. The main - objective of SMART-WORKFLOW is to integrate the last advances in high resolution mass spectrometry (HRMS) and statistical analysis of data to develop and optimize a smart methodology (workflow) for the assessment of the overall quality of wastewater - treatment. Treatments that will be evaluated include the ones (i) based only on physical processes (e.g. membrane filtration or carbon adsorption) where there is no change in the chemical identity of the pollutants and (ii) with changes in the - identity of the pollutants due to chemical reactions, including biological treatments or advanced treatments based on oxidation processes (AOPs). The generated workflow is understood as a procedural sequence for data acquisition, data processing and - data mining and it will be applicable to both already-known and new wastewater treatments, providing a rapid assessment on its performance regarding the removal of polar organic compounds and generated transformation products (TPs). The present - project aims to produce a substantial impact on the field of water research, one of the Europe’s Societal Challenges. - - 2020-03-15, Grant Agreement signed - - - 2018-03-16 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - SMART-WORKFLOW - - - H2020-MSCA-IF-2016 - - - 747698 - - - - - DE MONTFORT UNIVERSITY - - - EUR 183 454,80 - - - Trust based Decision Support Systems for Social Networks with Uncertain Knowledge - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - In real world decision-making, such as public security, social choice or recommender systems, we have a large body of data from various networked heterogeneous information sources or individuals that often conflict with each - other and provide inconsistent knowledge. It is a challenging task to yield an optimal consensus decision, given the range of individual decisions obtained in terms of these knowledge sources. This research proposal aims to create a novel - mathematical and computational framework for trust based social choice in networks and with uncertain knowledge by merging multiple individuals’ preferences in an adaptive manner to reduce the disagreements among them, and automatically seek a - decision or provide a recommendation with a maximal consensus. To achieve our goal, we propose to bring together, for the first time, four previously disparate strands of research: social network analysis, fuzzy preference modelling, multiple - attribute group decision-making and game theoretic modelling of malicious users. As a showcase the proposed framework will be incorporated to an e-health recommender platform to increase healthy lifestyle in cancer survivors. - - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - DeciTrustNET - - - H2020-MSCA-IF-2016 - - - 746398 - - - - - UNIVERSITA CA' FOSCARI VENEZIA - - - EUR 180 277,20 - - - The church of the Holy Apostles at Constantinople: the MYth and its Reception across the CEnturies - - - EUR 180 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - MYR - - 2019-06-04, ongoing project - - - 2017-06-05 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - MYRiCE - - - H2020-MSCA-IF-2016 - - - 745869 - - - - - Asociacion - Centro de Investigacion Cooperativa en Nanociencias - CIC NANOGUNE - - - EUR 170 121,60 - - - Device oriented molecular spin filter based interfaces - - - EUR 170 121,60 - - - Spain - - - Research Organisations - - We live in a constantly changing society in which information and communication are at the basis of our economy. To keep progressing is essential to investigate new feasible ways to control and manipulate information in order - to develop faster, smaller and less consuming devices. Organic Spintronics has emerged as a promising field to develop low-cost, mechanically-flexible and multi-functional devices in which information is carried not only by the charge but also by the - spin of electrons. However, the injection and transport of the spin information through a device remains challenging, being organic/inorganic interfaces key to overcome this limitation. DELICE addresses the interface engineering in organic - spintronics, aiming to profit from unique molecular capabilities for the development of highly performant chemically-tailored organic spintronic devices. In particular, DELICE focuses on exploiting the predicted spin filtering behavior of some - organometallic molecules to obtain highly spin-polarized interfaces, enhancing the spin injection from ferromagnetic surface or even creating spin-polarization on non-magnetic metal surfaces. These so-called spinterfaces will be implemented in - organic spintronic devices, spin valves, in order to determine the impact they have on the device performances. While organics have been mainly used as passive spacers in such devices, DELICE plans to go beyond the state of the art by actively - exploiting the molecule’s spin filtering capability to improve device performances. A thorough characterization of the spinterfaces properties together with their implementation in real devices will provide us with valuable knowledge about the role - of interfaces in devices. The technological potential of such a result represents a major step towards the realization of competitive organic nanodevices. The ultimate goal of DELICE is offering an interdisciplinary training to a promising young - female researcher. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - DELICE - - - H2020-MSCA-IF-2016 - - - 748459 - - - - - KARLSRUHER INSTITUT FUER TECHNOLOGIE - - - EUR 171 460,80 - - - Understanding the resilience of Amazonian floodplain ecosystems - - - EUR 171 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - The riparian forests that flank the major rivers in the Amazon Basin form a highly distinct ecosystem that connects the most biodiverse aquatic and terrestrial environments on the planet. These ‘flood forests’ are inundated - for periods of up to six months each year. But although submerged part of the year, flood forests are susceptible to forest fires during the dry season, especially in El Niño (ENSO) drought years. Surprisingly, flood forests poorly regenerate after - burning, and after repeated burning can transition to a savanna-like state in which the forest appears unable to regenerate altogether. Our previous field surveys and experiments suggest that seed dispersal limitations may play a fundamental role in - understanding the resilience of flood forests to fire perturbations. Fire destroys the seed bank completely. We hypothesise that forest regeneration is arrested by limited seed dispersal as burnt treeless stands affect fish communities and the - capacity to retain incoming seeds. Amazonian fishes heavily exploit flood forests during the rainy season. Most flood forest trees produce fruits and seeds during the time of high water, coinciding with the arrival of fishes. Fishes may play an - important role as dispersal agents for flood forest trees, as tree seeds have been found in the stomachs of >200 fish species. The reduced input of seeds in burned areas suggests that fishes avoid entering these sites, resulting in a positive - feedback that helps to keep these areas in a state of sparse tree cover. In the proposed research, we will assess the ecological barriers that explain arrested regeneration of Amazonian flood forests by evaluating the pathways of seed dispersal and - the effects of fire on the composition and abundance of fish communities. Understanding the regeneration of flood forests after fire will become increasingly relevant as extreme ENSO drought events and their associated fires are predicted to become - more frequent. - - 2019-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - RESILIENCE - - - H2020-MSCA-IF-2016 - - - 746181 - - - - - UNIVERSITA DEGLI STUDI DI PAVIA - - - EUR 168 277,20 - - - Molecular characterization of vesicle tethering complexes as novel regulators of collagen trafficking - - - EUR 168 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - Collagen maturation (through post-translational modifications, quaternary assembly and transport) is critical for tissues and organ development and homeostasis. This complex process involves numerous actors in different - sub-cellular compartments, which in turn depend on highly regulated trafficking systems. Although the mechanisms of vesicular trafficking, membrane tethering and fusion are conserved throughout eukaryotic evolution, highly specialized tethering - complexes have evolved to regulate specific fusion events. Recently, a novel pathway regulating collagen trafficking has been identified. Central to this pathway are two trafficking proteins, homologous to, but not part of, classical vesicle - tethering components. At present, very little is known about their specific functions. - - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - COTETHERS - - - H2020-MSCA-IF-2016 - - - 745934 - - - - - UNIVERSITY COLLEGE LONDON - - - EUR 195 454,80 - - - Astroglial control of axonal excitability, adaptation and analogue signalling - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Evidence has been emerging for astrocytes to play an important role in neuronal cooperation and information processing in the brain. Recent work has suggested that their activity may even regulate the shape of action - potentials in the axon and thus the efficacy of synaptic transmission. However, the underlying physiological machinery remains poorly understood. We propose here that astrocytes play an active role in the analogue-digital regulation of presynaptic - signalling. To decipher the role of astroglia in presynaptic signalling, in particular analogue-digital axonal information transfer, we focus on the giant mossy-fibre-CA3 synapse, well characterized in the host laboratory. Our working hypothesis is - that astrocytes regulate spike generation and propagation in axons by modulating local extracellular potassium and possibly by releasing glutamate. To test this hypothesis, an innovative set of technique will be used: i) direct recordings of - astrocytes and either presynaptic or postsynaptic elements of the synapse in the mossy-fibre to CA3 synapse; ii) genetic tools allowing specific targeting and stimulation of either astrocytes or neurons; iii) pioneering imaging tools, such as FLIM, - to directly measure the calcium entry and glutamate-sensing fluorescent reporter to reveal glutamate release by the astrocytes. The proposed project should unravel the mechanisms by which astrocytes control axonal information transfer in neural - networks axonal excitability while shedding light on poorly understood features of astrocyte physiology. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - AstroModulation - - - H2020-MSCA-IF-2016 - - - 746247 - - - - - UNIVERSITAET GRAZ - - - EUR 178 156,80 - - - Forbush decrease model for expanding CMEs affecting Earth and Mars - - - EUR 178 156,80 - - - Austria - - - Higher or Secondary Education Establishments - - Solar storms, also known as coronal mass ejections (CMEs), are the strongest drivers of space weather. During planetary impacts, they cause short term decreases in the galactic cosmic ray (GCR) flux, called Forbush decreases - (FDs). These depressions are observed in the interplanetary space, at the surface of the Earth and recently also on the Mars’ surface by the Curiosity Rover. A large subset of FDs is caused by interplanetary flux ropes (FRs), which expand during - their propagation based on observational studies. - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Austria - - - ForbMod - - - H2020-MSCA-IF-2016 - - - 745782 - - - - - UNIVERSITE DE GENEVE - - - EUR 175 419,60 - - - Catalysis with Chalcogen Bonds: Toward Artificial Enzymes - - - EUR 175 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - Major advances in science and technology are arising from the discovery and exploitation of new non-covalent interactions between molecules and the development of novel supramolecular functional systems. However, a limited - number of supramolecular interactions is available up to date. Therefore, the discovery of conceptually innovative, non-conventional approaches to create function should result in a breakthrough in current science. One of the most relevant functions - that can be implemented in molecular and supramolecular systems is the ability to catalyse chemical processes. Thus, the goal of this proposal is the integration of unorthodox non-covalent interactions, up to date mainly studied as a concept, into - practical applications in the field of catalysis. - - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - ChalEnz - - - H2020-MSCA-IF-2016 - - - 740288 - - - - - THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS - - - EUR 276 107,40 - - - Innovation through co-creation in contemporary mining relations: a new paradigm for stakeholder engagement at resource extraction project - - - EUR 276 107,40 - - - United Kingdom - - - Higher or Secondary Education Establishments - - This research project and training programme explore the contemporary practice and future potential of co-creation models in stakeholder engagement, and seek to define a new paradigm and design a new model for sustainable - resource relations in the mining industry. The call will generate cooperation between University of Queensland’s Centre for Social Responsibility in Mining, a globally recognised hub of innovation and research excellence into resource relations, and - University of St Andrews’ Centre for Pacific Studies, one of Europe’s leading research institutions with focus on the Pacific and, responding to the need for European expertise, will create new sites for European innovation and action in the - crucially important context of resource relations. The proposed research project will use an interdisciplinary toolkit of research methods capable of reaching and engaging comprehensively with a wide spectrum of corporate, indigenous and increasingly - influential ‘virtual’ stakeholders at mining projects in Papua New Guinea, uniquely mediating the nexus of resource host, industry and academy and moving beyond the dominant paradigm in resource relations. It will disrupt a series of well-established - preconceptions about the nature of relations between stakeholders in resource contexts, identify new spaces for industry innovation, and propose new, more responsible and sustainable solutions to stakeholder engagement at mining projects. This - project carries real potential to influence corporate and industry policies and actions, contributing to successful agreement making and Sustainable Development outcomes in resource relations. - - 2020-08-06, ongoing project - - - 2017-08-07 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - CC4M - - - H2020-MSCA-IF-2016 - - - 753272 - - - - - AALTO-KORKEAKOULUSAATIO - - - EUR 179 325,60 - - - Organic Polariton Laser Diode - - - EUR 179 325,60 - - - Finland - - - Higher or Secondary Education Establishments - - The high current density required for population inversion in organic semiconductors has made the realization of an organic laser diode rather challenging. Here, I propose an organic polariton laser diode (OPLD) in which the - threshold is achieved through the mechanism of polariton condensation. This conceptually different lasing mechanism does not require population inversion, suggesting that lasing under electrical injection can be, for the first time, demonstrated in - organic semiconductors. To date, most commercial laser diodes are based on inorganic semiconductors, which are expensive materials, require complex fabrication and manufacturing processes, and have a limited range of lasing wavelengths. Organic - semiconductors, in contrast, are ideal materials for the industrial production of diode lasers and other optoelectronic devices due to their ease of fabrication and processing, low acquisition-cost, and broad spectrum of emission. The realization of - the first OPLD within this fellowship will be tremendously important for the European market. In 2014, diode-laser technology comprised 46% of the total revenue ($9.4 billion) in the global laser market. Moreover, emerging automotive lighting (BMW - Laserlight) and high-definition laser display (LG LASER display) technologies could enable diode lasers to overtake the global laser market. Therefore, any steps towards the realization of the first organic laser diode (or organic solid state laser) - would represent a significant technological and scientific achievement. Furthermore, the proposed device offers a totally new, due to its electrical pumping, platform for fundamental studies of quantum fluids of light. - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Finland - - - OPLD - - - H2020-MSCA-IF-2016 - - - 745115 - - - - - INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE - - - EUR 185 076 - - - At the host-bacteria interface: Modulation of the intestinal microbiota and its metabolic activity by Card9 signalling in health and Inflammatory Bowel Diseases - - - EUR 185 076 - - - France - - - Research Organisations - - The microbial community in the human intestine is crucial to the health and nutrition of the host. Loss of the fragile balance within this complex ecosystem is involved in numerous pathologies, including inflammatory bowel - disease (IBD). The incidence of IBD is increasing and affects individuals in challenging years of their lives, with immunosuppressive treatments that are not always effective. - - - 2019-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - MArylAND - - - H2020-MSCA-IF-2016 - - - 743576 - - - - - UNIVERSITE DE GENEVE - - - EUR 265 840,20 - - - Targeting CRISPR-based HDAC inhibitors to histones: a new tool for assessing mechanisms of class I HDAC inhibitors and developing chemical probes. - - - EUR 265 840,20 - - - Switzerland - - - Higher or Secondary Education Establishments - - Cancer is responsible for 8.5 million deaths worldwide each year, representing a considerable burden for society. In cancer cells, tumor repression genes are deactivated by epigenetic mechanisms. The accessibility of DNA to - transcription factors is determined in part by the chemical modifications of histones, proteins that pack DNA into condensed chromatin. When histones are deacetylated by histone deacetylases (HDACs), the chromatin structure is even more packed, - preventing gene expression. HDAC inhibitors are epigenetic drugs currently in the market, able to increase histone acetylation, unpacking DNA for gene transcription. However, the specific mechanisms leading to the success or failure of those drugs - are poorly understood, leading to unpredictable therapeutic outcomes. HDAC inhibitors are expected to interact with HDACs in the cell nucleus. However, fluorescence-labeling has revealed HDAC inhibitors to locate mostly outside the nucleus in living - cells, suggesting that their genomic effects represent only part of their activities. This project aims at developing a set of tools, using a modified genome-editing method and a fluorescent chemical probe combined with genome-wide assays to - understand specifically the genomic mechanisms of HDAC inhibitors. We will develop the CRISTONE (CRISPR-based HDAC inhibitor targeted to histones) tool to allow targeted HDAC inhibition. We will target an HDAC1 inhibitor (a histone tail peptide) - specifically to repressed loci in the genome of HDAC1-overexpressing HEK 293T cells. To understanding the transcriptional consequences of targeted and untargeted HDAC1 inhibition, the CRISTONE effects will be compared to those of a new fluorescent - chemical probe capable of inhibiting nuclear HDACs. To assess the cellular phenotypic outcome, we will test the genome-wide cellular effects on transcription and chromatin accessibility, giving insights into the specific effects of genomic, targeted - HDAC inhibition. - - 2020-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Switzerland - - - CRISTONE - - - H2020-MSCA-IF-2016 - - - 750190 - - - - - UNIVERSITA DEGLI STUDI ROMA TRE - - - EUR 168 277,20 - - - Historical Small Smart City Protocol for integrated interventions. - - - EUR 168 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - "Over the last decade, the urban conservation challenge has grown critical due to rapid urbanization and the resulting growth and transformation of cities worldwide. Conserving historic urban environments is currently one of - the most universally urgent and challenging cultural heritage conservation issues. The research project "Hismacity-pro" aims to develop a detailed protocol of multidisciplinary integrated interventions targeted at the recovery and revitalization of - small historic centers by enabling smart city services, in order to improve the quality of life in these settlements, which are usually confined within marginal areas, far from the biggest cities. The protocol will be able to be replicated in other - southern European towns with the same needs. At the moment, Italian small centers haven’t been rigorously mapped and requalified and local policies aimed at their recovery are quite absent, while the Italian Agency for Territorial Cohesion has - recently set up a central policy for their valorisation. The protocol will be adoptable by this strategy and will convey an operative tool of guidance for municipalities in peripheral areas on policy management, in central Italy and Catalonia - (Spain). The research will be grounded in an holistic management of sites and their surrounding context and will encourage a considerable increase in the competitiveness of small historic centers, as well as their conservation and economic - sustainable growth. The project will assess the state of information available to practitioners and identify unmet needs in the conservation of historic cities and urban settlements. It will also try to find a response to how small historic towns can - use local assets to revitalize their economy, and the logic of turning problems into resources will be adopted (“smart” growth). The protocol will foster interventions tailored to the real needs of Euro-mediterranean historic small towns under - marginal conditions." - - 2019-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - HISMACITY-pro - - - H2020-MSCA-IF-2016 - - - 743837 - - - - - UNIVERSITY OF NATIONAL AND WORLD ECONOMY - EKONOMICKA UNIVERZITA V BRATISLAVE - INDUSTRIALEN KLASTER ELEKTROMOBILI - Finance & Banking, Associazione per lo Sviluppo Organizzativo e delle Risorse Umane - UNIVERSITA DEGLI STUDI ROMA TRE - ARISTOTELIO PANEPISTIMIO THESSALONIKIS - SLOVENSKA ASOCIACIA PRE ELEKTROMOBILITU - - - EUR 1 525 500 - - - Electromobility in urban transport: a multi-dimensional innovation (socio-economic and environmental effects) - - - EUR 1 525 500 - - - Bulgaria - Slovakia - Bulgaria - Italy - Italy - Greece - Slovakia - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - Other - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Other - - At present, transition towards electromobility in urban transport and related companies are among the most studied industrial areas. Different EU countries implement different methodological and business approaches to - investigate the possibilities for the acceleration of electromobility integration in urban transport. Studies on these approaches to be shared within the project consortium and with different stakeholders (local authorities, producers of electric - vehicles and recharging stations) will provide the basis of the initiative for increasing the interest in electromobility integration in urban transport as a multi-dimensional innovation. The thin red line of electromobility practical integration - passes through the sharing of innovative ideas with relevant stakeholders by carrying out field studies, in-depth interviews and electronic on-line studies. - - 2020-02-29, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Bulgaria - - - eMobilita - - - H2020-MSCA-RISE-2016 - - - 734459 - - - - - TECHNISCHE UNIVERSITAET MUENCHEN - - - EUR 171 460,80 - - - Dynamical Phenomena in Quantum Many-Body Systems - - - EUR 171 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - We will study dynamical phenomena in strongly interacting quantum systems, which currently receive increased attention due to recent experimental, numerical and theoretical breakthroughs. Our research will push the limits of - the state of the art of numerical simulations in this context by bringing together experts (the ER and the host group) on different aspects of this topic in an outstanding research environment in Munich with an excellent infrastructure and a - clustering of theoretical and experimental groups with the potential to world class collaborations. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Germany - - - QMBDyn - - - H2020-MSCA-IF-2016 - - - 747914 - - - - - VRIJE UNIVERSITEIT BRUSSEL - - - EUR 160 800 - - - The European Commission in Drone Community: a New Cooperation Area in the Making - - - EUR 160 800 - - - Belgium - - - Higher or Secondary Education Establishments - - The objective of this research is to examine how the European Commission is shaping regulatory framework development, production and use of drones considering the diverging interests among actors concerned in Europe (and - beyond) where multiple authorities overlap. A comprehensive analysis of drones operations as a whole, including actors’ perceptions, expectations, interests and practices is still lacking. This research will therefore study the European Commission’s - strategy to join and shape the drone community (rule makers, interest groups, manufacturers, operators and users) as well as the impact of its action. Referring to the Commission’s policy entrepreneurship literature, it is interested in how the - Commission, by building on its competencies and resources, has exercised its leadership capacity to initiate action in a new domain that may not fall de facto under its prerogatives and thus has an effect on a strategic industry. Based on a - relational approach, the project will analyse the power structures (configuration of relations, diverging and converging interests, resources, skills), perceptions of issues at stake (discourses) and action rationale (cooperation dynamics, informal - and formal practices, strategies and means) of actors involved in EU initiatives: the single drones market, the regulatory framework, as well as research and development. The research methodology will be qualitative and based on a triangulation of - methods (documents, discourses and interviews analysis). In line with the researcher’s previous work on the Commission’s actions in the security sector, it will be argued that the Commission’s leadership in drone matters, regarding its market, - regulation and development, offers a lever for action to strengthen its position in the field of security at the crossroads between all actors involved as a bridge between the internal and external security, civil and military dimensions. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Belgium - - - EU-Drones - - - H2020-MSCA-IF-2016 - - - 747947 - - - - - FONDAZIONE TELETHON - FONDAZIONE TELETHON - - - EUR 150 000 - - - Developing a cure for retinitis pigmentosa due to Usher syndrome - - - EUR 150 000 - - - Italy - Italy - - - Research Organisations - Research Organisations - - The GeneVision proof-of-concept project spins from a major discovery made by the principle investigator (PI) within the RetGeneTx ERC project demonstrating that dual AAV vectors expand AAV DNA transfer capacity in the retina - thus allowing delivery of genes whose size cannot be packaged in single AAVs. Thus, dual AAV vectors allow gene therapy of those inherited blinding conditions, like Usher syndrome type Ib (USHIB), Stargardt disease or other forms of retinitis - pigmentosa, due to mutations in large genes from which the AAV platform, the best to date for in vivo gene therapy, was so far precluded. - - - 2018-09-30, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Italy - - - GeneVision - - - ERC-2016-PoC - - - 755075 - - - - - UNIVERSITE DE LIEGE - UNIVERSITE DE LIEGE - - - EUR 147 000 - - - NI2D: Software for nonlinear vibration analysis: From identification to design. - - - EUR 147 000 - - - Belgium - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Nonlinear vibrations are a frequent occurrence in engineering structures and can originate from friction, contact, material laws and large displacements. Nonlinear phenomena are most often ignored or avoided in industry, - because practitioners lack both a methodology and a software for properly addressing them. - - 2019-03-31, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Belgium - - - NI2D - - - ERC-2016-PoC - - - 737610 - - - - - UNIVERSITY OF KEELE - UNIVERSITY OF KEELE - - - EUR 1 998 696 - - - DNA dynamics in the unusual cell cycle of the malaria parasite Plasmodium falciparum - - - EUR 1 998 696 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This proposal promises to transform our understanding of the basic biology of the malaria parasite Plasmodium, and of how that biology affects virulence. Remarkably little is known about the Plasmodium cell cycle, despite a - wealth of knowledge on the subject in model cells. This project will reveal, with unprecedented resolution, how DNA replication is organised in Plasmodium and how changing conditions in the human host and exposure to antimalarial drugs affect it. - - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - PlasmoCycle - - - ERC-2016-COG - - - 725126 - - - - - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - - - EUR 150 000 - - - From Neurons to Robots: Non-Invasive, General-Purpose Interfacing With Human Spinal Motor Neurons - - - EUR 150 000 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - INTERSPINE (“From Neurons to Robots: Non-Invasive, General-Purpose Interfacing With Human Spinal Motor Neurons”) aims at exploiting the methodologies developed during the ERC Advanced grant DEMOVE (“Decoding the Neural Code of - Human Movements for a New Generation of Man-machine Interfaces”). During DEMOVE, novel bioelectrodes and computational methods have been developed to enrich our fundamental understanding of the mechanisms underlying the generation of human movements, - from the cellular level to the function. These methods also contributed to the development of new schemes for controlling bionic limbs to substitute missing ones in amputees. INTERSPINE will translate these methods, and specifically those based on - non-implanted electrodes, to develop a more robust general system that extracts neural information (at the individual cell level) from the human spinal cord and transforms it into extremely accurate commands to external devices, such as prosthesis, - general purpose and teleoperated robots, and computer interfaces. This will be the only non-invasive man-machine interface based on direct neural activity (spiking of neural cells). The ERC Grant DEMOVE demonstrated in laboratory conditions that this - approach is feasible and allows the identification of the exact timing of each activation of neural cells in the spinal cord, known as motor neurons. INTERSPINE will extend this approach through wearable devices and real-time processing, as well as - with a robust association between the identified neural activity and external commands to devices, with the aim of revolutionizing everyday man-machine interfacing. The direct decoding of neural activity will provide unprecedented accuracy and - robustness with respect to other non-invasive approaches. - - 2018-12-31, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - INTERSPINE - - - ERC-2016-PoC - - - 737570 - - - - - DEUTSCHES ZENTRUM FUR NEURODEGENERATIVE ERKRANKUNGEN EV - DEUTSCHES ZENTRUM FUR NEURODEGENERATIVE ERKRANKUNGEN EV - - - EUR 1 806 068 - - - Dendritic encoding of movement in space - - - EUR 1 806 068 - - - Germany - Germany - - - Research Organisations - Research Organisations - - Understanding the neuronal basis of behaviour is a central quest for neuroscience. Neurons are the fundamental units of computation in the brain. Thus, any attempt at unravelling the relationship of neural networks activity - and behaviour must be based on an understanding of the transformation of inputs to outputs in single neurons. One of the greatest challenges that our field faces is to make sense of inputs. Without knowing how different synaptic inputs are engaged - during behaviour, it is impossible to decode the neuronal input to output conversion. We have developed an approach that allows both the dissection of inputs and the prediction of output during behaviour. We will apply this functional decoding - approach to pyramidal neurons in the dorsal subiculum. These neurons form a hippocampal-neocortical interface and are important for memory-guided navigation. The output of subicular neurons contains a dense, distributed representation of space, but - the functional input diversity is unresolved. Following the generation of a spatial tuning map during navigational tasks with two-photon Ca2+ imaging at cellular-resolution, we will map the input origins of individual neurons by using targeted - single-cell initiated mono-transsynaptic tracing. Then, we will dissect the function of the input from different origins by chemogenetic silencing of input synapses. As a central component of the project, we will map dendritic input patterns in - navigating mice with two-photon imaging of Ca2+ transients on dendritic spines. These patterns will be incorporated into a data-driven biophysical model capable of converting realistic synaptic inputs into output. We will tune the model parameters - using whole-cell patch-clamp recordings during free behaviour. The final models will be capable of predicting the membrane potential of subicular neurons from precise behavioural observations, offering exciting new perspectives for network analysis - and neuroengineering. - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - SUBDECODE - - - ERC-2016-COG - - - 725693 - - - - - KING'S COLLEGE LONDON - KING'S COLLEGE LONDON - - - EUR 2 000 000 - - - Functions of plasticity in adult-born neurons - - - EUR 2 000 000 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The major objective of FUNCOPLAN is to examine groundbreaking questions on the functional role of newly-generated neurons in the adult brain. Using a combination of innovative approaches, our aim is to discover how plasticity - in adult-born cells shapes information processing in neuronal circuits. - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - FUNCOPLAN - - - ERC-2016-COG - - - 725729 - - - - - UNIVERSITEIT UTRECHT - UNIVERSITEIT UTRECHT - - - EUR 2 000 000 - - - The Senses of Islam: A Cultural History of Perception in the Muslim World - - - EUR 2 000 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The aim of SENSIS is to write a cultural history of the senses in Islam, by examining how the senses have been conceptualised, and calibrated, in a variety of Muslim environments. Sensory perception is not only a physical but - also a cultural act: how people experience and understand sight, sound, smell, taste, and touch differs according to the historical, geographical, social and intellectual contexts in which perception occurs. Accordingly, this project comprehensively - studies the Muslim sensorium, past and present. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - SENSIS - - - ERC-2016-COG - - - 724951 - - - - - UNIVERSITE PARIS DIDEROT - PARIS 7 - UNIVERSITE PARIS DIDEROT - PARIS 7 - - - EUR 2 198 150,99 - - - Smart Lab-On-Chips for the Real -Time Control of Cells - - - EUR 2 198 150,99 - - - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Cells are complex, autonomous genetic machines with rich information processing capabilities. Synthetic Biology builds on these properties to design novel, synthetic genetic programs in cells with the aim of benefiting humans. - Yet, safety and efficiency issues require creation of synthetic circuits that are reliable over a large range of operating conditions and stable to all sorts of perturbations. This is a tremendous challenge for synthetic biologists, as the robustness - of any circuit is limited by their high dependence on the cellular host machinery and the fundamental stochastic nature of gene expression. Taking inspiration from physics and engineering we have imagined a computer-based feedback loop that can - remotely, in real-time, control the state of a synthetic genetic program running in cells. Here, we will combine microfluidics, optogenetics, structured illumination, inference methods and control algorithm into such a real time control device of - gene expression for yeast cells. We will then study how cells can be controlled at different scales and with increasing levels of complexity from a simple circuit to a simple multicellular ecosystem. Specifically, we aim at: - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - France - - - SmartCells - - - ERC-2016-COG - - - 724813 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 999 780 - - - Epigenomics and chromosome architecture one cell at a time - - - EUR 1 999 780 - - - France - France - - - Research Organisations - Research Organisations - - In Eukaryotes, cellular identity and tissue-specific functions are linked to the epigenetic landscape and the multi-scale architecture of the genome. The packing of DNA into nucleosomes at the ~100 bp scale and the - organization of whole chromosomes into functional territories within the nucleus are well documented. At an intermediate scale, chromosomes are organised in megabase to sub-megabase structures called Topologically Associating Domains (TADs). - Critically, TADs are highly correlated to patterns of epigenetic marks determining the transcriptional state of the genes they encompass. Until now, the lack of efficient technologies to map chromosome architecture and epigenetic marks at the - single-cell level have limited our understanding of the molecular actors and mechanisms implicated in the establishment and maintenance of the multi-scale architecture of chromosomes and epigenetic states, and the interplay between this architecture - and other nuclear functions such as transcription. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - France - - - EpiScope - - - ERC-2016-COG - - - 724429 - - - - - MEDICAL RESEARCH COUNCIL - MEDICAL RESEARCH COUNCIL - - - EUR 1 990 125 - - - Understanding the complexity and architecture in protein ubiquitination - - - EUR 1 990 125 - - - United Kingdom - United Kingdom - - - Research Organisations - Research Organisations - - The posttranslational modification of proteins with polyubiquitin regulates virtually all aspects of cell biology. This versatility arises from eight distinct linkage types between individual ubiquitin moieties in - polyubiquitin, which co-exist in cells, are independently regulated, and eventually determine the fate of the modified protein. However, ubiquitin chain architecture can be highly complex, and the extent of ‘chain branching’ is unknown. Moreover, - ubiquitin also undergoes phosphorylation and acetylation, which can dramatically alter its function. - - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - UbiArchitect - - - ERC-2016-COG - - - 724804 - - - - - CARL VON OSSIETZKY UNIVERSITAET OLDENBURG - CARL VON OSSIETZKY UNIVERSITAET OLDENBURG - - - EUR 1 500 000 - - - Individualized Binaural Diagnostics and Technology - - - EUR 1 500 000 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Humans have two ears – and for good reason: So-called binaural hearing is critical not only for localizing acoustic events but also for selectively focusing on a target sound while suppressing sound from other directions. In - order to perform these tasks, neural circuits with the most temporally precise processing within the entire nervous system have evolved. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - IBiDT - - - ERC-2016-STG - - - 716800 - - - - - SWANSEA UNIVERSITY - SWANSEA UNIVERSITY - - - EUR 1 996 042,50 - - - The true costs of bird flight: From the laboratory to the field - - - EUR 1 996 042,50 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Flight is thought to be one of the most energetically costly of bird activities. These costs matter by virtue of their magnitude, as factors affecting flight costs can have a disproportionate impact on the overall energy - balance. Flight costs are fundamentally linked to airflows, as well as behavioural responses to them, because birds react to horizontal and vertical currents by changing flight mode (i.e. flapping/ gliding), speed and route. Even minor route - adjustments can radically affect the flow conditions that birds experience due to the uniquely dynamic and heterogeneous nature of the aerial environment. Yet our understanding of how airflows impact birds is in its infancy, being constrained by a - lack of information on the metabolic costs of flight. Currently, the main methods for measuring flight costs in the laboratory either restrain the bird (thereby increasing energy expenditure) or suffer from low resolution, and field methods do not - allow costs to be resolved in relation to fine scale movement paths. FLIGHT will use interdisciplinary approaches, integrating laboratory and field techniques, to address these grand challenges. Breakthrough methodologies will be used to (1) measure - the costs of unrestrained bird flight in the laboratory and (2) derive a new proxy for power use in flight that is linked to flight performance, using accelerometry measurements from cutting-edge data loggers. Loggers will then be (3) deployed on - wild birds to quantify their responses to airflows and the energetic consequences over fine scales. This will provide completely novel, mechanistic insight into the way the physical environment impacts flight costs, and (4) enable variation in - flight–related energy expenditure to be modelled geographically and seasonally in model species. Overall, FLIGHT will provide new macro-ecological insight into relationships between bird distributions and flow conditions and inform assessments of how - birds may be affected by changing wind regimes. - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - FLIGHT - - - ERC-2016-STG - - - 715874 - - - - - UNIVERSITEIT UTRECHT - UNIVERSITEIT UTRECHT - - - EUR 1 500 000 - - - Cooperative Acceptor Ligands for Catalysis with Earth-Abundant Metals - - - EUR 1 500 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Homogeneous catalysis is of prime importance for the selective synthesis of high added value chemicals. Many of the currently available catalysts rely on noble metals (Ru, Os, Rh, Ir, Pd, Pt), which suffer from a high toxicity - and environmental impact in addition to their high cost, calling for the development of new systems based on first-row transition metals (Mn, Fe, Co, Ni, Cu). The historical paradigm for catalyst design, i.e. one or more donor ligands giving electron - density to stabilize a metal center and tune its reactivity, is currently being challenged by the development of acceptor ligands that mostly withdraw electron density from the metal center upon binding. In the last decade, such ligands – mostly - based on boron and heavier main-group elements – have evolved from a structural curiosity to a powerful tool in designing new reactive units for homogeneous catalysis. - - - 2022-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - CALCEAM - - - ERC-2016-STG - - - 715060 - - - - - THE UNIVERSITY OF WARWICK - - - EUR 183 454,80 - - - Sparse Robust Expander with Applications in Combinatorial Embedding Problems - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Expanders is a fundamental concept in combinatorics. From the application point of view, expanders have become a powerful tool in studying real life problems such as network design and error correcting codes. From the - theoretical point of view, it is considered as a sparse analogue of Szemeredi's regularity (recognised by the 2012 Abel prize) with connections in algebra, analysis, geometry and topology. - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SREACEP - - - H2020-MSCA-IF-2016 - - - 752426 - - - - - UNIVERSITA DEGLI STUDI ROMA TRE - UNIVERSITA DEGLI STUDI ROMA TRE - - - EUR 1 235 875 - - - Universality in Condensed Matter and Statistical Mechanics - - - EUR 1 235 875 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Universality is a central concept in several branches of mathematics and physics. In the broad context of statistical mechanics and condensed matter, it refers to the independence of certain key observables from the - microscopic details of the system. Remarkable examples of this phenomenon are: the universality of the scaling theory at a second order phase transition, at a quantum critical point, or in a phase with broken continuous symmetry; the quantization of - the conductivity in interacting or disordered quantum many-body systems; the equivalence between bulk and edge transport coefficients. Notwithstanding the striking evidence for the validity of the universality hypothesis in these and many other - settings, a fundamental understanding of these phenomena is still lacking, particularly in the case of interacting systems. - - - 2022-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Italy - - - UniCoSM - - - ERC-2016-COG - - - 724939 - - - - - KOBENHAVNS UNIVERSITET - - - EUR 200 194,80 - - - Expert Rule? Judges, Lawyers, and the Practices of Interpretation in International Criminal Law - - - EUR 200 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - Since the end of the Cold War, the number of international courts has increased significantly, indicating a growing judicialisation of global governance. At the same time, international judges have begun to change and - potentially even create law through their decisions. In international criminal law, a particularly drastic example, international judges repeatedly described the development of international criminal law as one of their main achievements. But have - these courts, 15 years after the Rome Statute of the International Criminal Court entered into force, been able to deliver on their objective? How far do judicial interpretations matter in global governance more broadly? Applying an innovative - interdisciplinary approach that draws on legal theory, this project (EaRL) capitalises on the recent “practice turn” in International Relations theory to develop a novel theoretical and empirical account of interpretive judicial authority in global - governance. EaRL is based on a systematic analysis of all 240 available judgements of international criminal and hybrid courts, including the International Criminal Court, the ad hoc Tribunals for the former Yugoslavia (ICTY) and Rwanda (ICTR), and - the Special Court for Sierra Leone (SCSL). In addition, it uses over 40 in-depth expert interviews with international judges, staff at civil society organisations, and government representatives. Ideally located at iCourts, the University of - Copenhagen’s globally leading Centre of Excellence for International Courts, EaRL will enable the experienced researcher to complete her interdisciplinary training and to make a timely contribution to the Centre’s impressive body of knowledge on - international courts. In addition to its academic impact, EaRL ultimately aims to enhance the judgement-writing process at international criminal courts and to improve the general public’s understanding of international criminal justice. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - EaRL - - - H2020-MSCA-IF-2016 - - - 748114 - - - - - THE UNIVERSITY OF WARWICK - - - EUR 183 454,80 - - - Galois Representations and Diophantine Problems - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Wiles' remarkable proof of Fermat's Last Theorem paved the way for the modular approach to Diophantine equations. This associates a Frey elliptic curve to a putative solution of a Diophantine equation and studies it using - Galois representations and modularity. This proposal is organized around two research programmes, both of which develop new tools for the modular approach. The first is concerned with distinguishing Galois representations; this is currently the most - frequent obstruction to the success of the approach. The second aims to prove modularity and irreducibility theorems for abelian varieties of GL2 type. Such theorems are of tremendous independent interest, but will also allow the replacement of Frey - elliptic curves with Frey abelian varieties giving the modular approach immense flexibility. - - 2020-02-29, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - GalRepsDiophantine - - - H2020-MSCA-IF-2016 - - - 747808 - - - - - ACADEMISCH ZIEKENHUIS LEIDEN - ACADEMISCH ZIEKENHUIS LEIDEN - - - EUR 1 500 000 - - - Rheumatoid Arthritis Caught Early: investigating biological mechanisms preceding chronification of joint inflammation to identify patients prior to presentation of classic chronic arthritis - - - EUR 1 500 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Rheumatoid Arthritis (RA) causes long lasting disability. At the time of clinically evident arthritis and diagnosis, the disease is already persisting, requiring long-term suppressive treatment. My overarching aim is to - prevent chronic arthritis and RA by inhibiting the evolving auto-immune response in a pre-arthritis phase. Currently, identification of RA-patients before the classic presentation with clinically evident chronic arthritis is beyond the state of the - art. I here aim to achieve this early recognition by increasing the mechanistic understanding of pre-arthritis phases. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - RACE - - - ERC-2016-STG - - - 714312 - - - - - UNIVERSITEIT LEIDEN - UNIVERSITEIT LEIDEN - - - EUR 1 499 853 - - - Lost in Transition? Multiple Interests in Contexts of Education, Leisure and Work - - - EUR 1 499 853 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - “I am going to graduate! But what exactly should I do next?” All adolescents face this question when moving to postsecondary education or early career. Essential for sustainable choices in education and career is consolidating - one’s interest. Yet, exactly this step appears to be difficult, with many adolescents feeling lost, switching programmes, or regretting their choices afterwards. - - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - INTERESTS - - - ERC-2016-STG - - - 716183 - - - - - CONSIGLIO NAZIONALE DELLE RICERCHE - - - EUR 180 277,20 - - - EXTREME ENVIRONMENT RESISTANT NANOPHOTONICS - - - EUR 180 277,20 - - - Italy - - - Research Organisations - - Nanophotonic extreme environment sensors are expected to lead to revolutionary advancements in aerospace, nuclear, wellbore exploration and environmental bio-chemical sciences. Extreme environments are those where the - physico-chemical conditions render standard materials completely unusable; including strongly ionizing radiation, high erosion, high corrosion, or temperatures beyond 1600°C in aircraft and aerospace applications. Recently, yttrium aluminum garnet - (YAG) crystals have been identified as harsh environment resistant optical material thanks to its unique combination of outstanding optical properties and high melting temperature (1970°C), chemical inertness and hardness. It´s use for developing - extreme environment nanophotonic on-chip instruments is therefore of high interest. However, micro/nanostructuring YAG crystalline components is currently impossible due to its capability to withstand corrosion in plasma etching chambers, its - hardness, and its fracturing under high micro-stress loading machining or milling industrial processes. The central question that this project aims to solve is: - - 2019-05-01, ongoing project - - - 2017-05-02 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - EXTREMELIGHT - - - H2020-MSCA-IF-2016 - - - 747055 - - - - - UNIVERSITY OF SOUTHAMPTON - UNIVERSITY OF SOUTHAMPTON - - - EUR 1 998 927,51 - - - Mechanical Chirality: Synthesis, Properties and Applications at a New Horizon in Supramolecular Stereochemistry - - - EUR 1 998 927,51 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Molecular chirality is a central theme in chemistry; in 2015 approximately 13% of publications in J. Am. Chem. Soc. and 12% in Angew. Chem. concerned chirality. All previously studied forms of molecular asymmetry (central, - axial, planar and helical chirality) have found applications throughout the sub-disciplines of chemistry including as catalysts, materials and sensors. - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - MechaniChiral - - - ERC-2016-COG - - - 724987 - - - - - STICHTING KATHOLIEKE UNIVERSITEIT - - - EUR 165 598,80 - - - Imaging the Motion of Magneto-Excitons in New Emerging Materials - - - EUR 165 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Recently discovered two-dimensional (2D)-honeycomb semiconductor materials have two inequivalent, degenerate valleys in their electronic band structure. This leads to a new “valley” degree of freedom known as pseudospin that, - similar to real spin, has been proposed as an extra information carrier for new classes of electronic and optoelectronic devices. Monolayer transition-metal dichalcogenides (TMDs) are an important type of 2D material, in which, due to the strong 2D - confinement and a reduced dielectric screening of the Coulomb interactions, electron-hole (e-h) correlations are extremely strong. This results in creation of e-h pairs (excitons) that are so strongly bound that excitonic effects completely dominate - the optical properties of TMDs even up to room temperature. The pronounced excitonic effects in single-layer TMDs, therefore, provide a unique opportunity to investigate strong light-matter interactions associated with valley effects exhibiting - exotic behaviour. However, the key fundamental question regarding the exact excitonic band structure, the valley-exciton energy-momentum (dispersion) relationship, and the corresponding excitonic transport properties, remains open. - - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - IMME-NEM - - - H2020-MSCA-IF-2016 - - - 746762 - - - - - WEIZMANN INSTITUTE OF SCIENCE - WEIZMANN INSTITUTE OF SCIENCE - - - EUR 150 000 - - - Growth detection and quantification (GDQ) - - - EUR 150 000 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The growth rate of both bacterial and human cells has a central role in the clinical management of infectious diseases and malignancies. Virulent and aggressive bacterial strains have higher growth rates, which will decrease - in response to successful treatment. Proliferation rates are also instrumental in the diagnosis, prognosis, and treatment of various cancer types, as the proliferation rate of human cells is one of the hallmarks of malignancy, evident by the - widespread use of various proliferation indices such as mitotic figure counting, PCNA and Ki-67 antibodies. An integral part of cell growth is DNA replication; in mid-replication, each replicating cell will have a second, partial, currently - synthesized genome. This creates variations in DNA copy-number along the genome across a population of cells from which growth-rate is inferable. Based on our novel ERC-funded method, which accurately measures bacterial growth rates from metagenomic - samples, we will further the development of our methods towards obtaining an entirely new facet of information about pathogens in infectious diseases, or an accurate estimation of tumor proliferation rates. Our approach is expected to be superior to - the current state-of-the-art as sample preparation is simple and requires no immunological staining or examination by an experienced pathologist, increasing validity and reproducibility. - - 2018-09-30, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Israel - - - Prolifimeter - - - ERC-2016-PoC - - - 737419 - - - - - THE UNIVERSITY OF WARWICK - - - EUR 183 454,80 - - - Birational and Tropical Methods in Geometry - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - We propose major advances in several fundamental questions of algebraic geometry, centering around the invariants of varieties, that we will attack on two fronts. One direction considers birational invariants and rationality - properties. The other studies deformation properties of varieties, especially in terms of curve-counting invariants. Accordingly, we divide the material into three main projects. In the first, we will prove rationality theorems for many new - birational quotients obtained via divided powers. The second project sets up a novel method of counting tropical curves, that will lead to results on tropical correspondences. Our third project extends the ideas of the second, proving deep - enumerative results in log geometry; we expect this to provide a state-of-the-art enumerative interpretation of the divisor-line bundle equivalence in log tropical terms. The University of Warwick is the ideal venue for this research. The PI will - benefit from the extensive experience of Miles Reid and Christian Böhning, world experts in birational geometry and the modern study of rationality questions, and from collaboration with Diane Maclagan, an acknowledged authority in tropical geometry. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - BTMG - - - H2020-MSCA-IF-2016 - - - 746554 - - - - - UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN - - - EUR 187 866 - - - Investigation of adaptive design and rewiring of Survival-Apoptosis-Mitogenic (SAM) signalling transduction network - - - EUR 187 866 - - - Ireland - - - Higher or Secondary Education Establishments - - Cell life is not the property of any single protein or gene; rather it emerges from concerted actions of multiple molecules in cellular networks. Current proposal is focused on Signal Transduction Networks (STN) connecting the - environment to cell responses. A major challenge is to understand how STN integrate and process environmental signals in a robust and reliable way and how they “compute” cell fate decisions depending on genetic background. To answer this question, - the study will be focused on three interconnecting STNs: the Survival (PI3K/PTEN/AKT), Apoptotic (RASSF1/MST/LATS) and Mitogenic (EGFR/RAS/RAF/MEK/ERK) pathways, the SAM network. In the scope of current proposal the methods of signalling network - reconstruction will be improved and the SAM network topology will be reconstructed in the panel of cell lines. Based on available data and reconstructed network topology the mechanistic site-specific dynamic model of SAM network will be developed and - validated. Model predictions of dependence of signalling outputs behaviour on different perturbations (like small molecule inhibitors and their combinations) and background (mutations and protein expression levels) will be validated. The signalling - outputs will be experimentally correlated to the cell fate decisions. - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Ireland - - - SAMNets - - - H2020-MSCA-IF-2016 - - - 750688 - - - - - UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN - - - EUR 187 866 - - - Childhood Self-Control, Social Conditions, and Adult Health - - - EUR 187 866 - - - Ireland - - - Higher or Secondary Education Establishments - - The capacity to delay gratification and control impulses emerges in childhood and may profoundly shape the lifestyle behaviours and resulting health conditions that afflict many and burden health systems across Europe and rest - of the world. Childhood self-control appears to be malleable and as such has been identified by policy-makers as a key prevention target with potential long-run benefits. Yet, empirical evidence demonstrating links from early self-control to adult - outcomes remains scarce. This Fellowship will inform estimates of the benefits of fostering self-control by drawing on under-exploited childhood self-control measures from six pre-existing large scale (N>1,000) prospective studies of individuals - whose health behaviour and health has been tracked for up to 55 years. Already, using these incredible resources the applicant has identified how childhood self-control predicts population patterns of smoking and weight gain across life. He now aims - to advance this work and the scientific literature by identifying: (i) the specific life-span health consequences of early self-control (e.g. biomarkers, chronic conditions, mortality rates), (ii) the key behavioural and socioeconomic pathways that - explain these linkages, and (iii) the social conditions where self-control may have the greatest health impact. The Fellowship will both enrich and benefit from the strengths of the host institution in Childhood and Human Development research. Strong - input from a world-leading researcher in this area, Prof. Richard Tremblay, will help enable the applicant to make a disciplinary shift from behavioural medicine to an integrated life-course perspective where adult health is viewed through the lens - of child development. This interdisciplinary mobility coupled with a strong programme of advanced training will ensure the Fellowship rapidly advances both the applicant’s career development and the exciting programme of work outlined in this - proposal. - - 2020-03-14, Grant Agreement signed - - - 2018-03-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Ireland - - - SELFCONTROLHEALTH - - - H2020-MSCA-IF-2016 - - - 750169 - - - - - KOBENHAVNS UNIVERSITET - - - EUR 212 194,80 - - - Microfoundations of International Order - - - EUR 212 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - "This project aims to investigate the microfoundations of international order. How do international orders emerge? How are they imagined, created, and maintained? What will be the future of the current international order? - These and other similar questions continue to be of interest for scholars of international relations (Bull 1977; Brooks and Wohlfort 2008; Ikenberry 2012; Kupchan 2012; Sorensen 2011; Dunne and Flockhart 2013; Zakaria 2008; Hurrell 2008; Schweller - 2014; Miskimmon et.al. 2013). Most of this literature looks at the macro picture, dealing with structural factors such as distribution of power, differential economic development, changing patterns of interdependence, and demographics to explain why - and how international orders came to be. However, the issue of microfoundations has been largely overlooked, if not totally ignored. - - 2019-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - MICROFOUNDATIONS - - - H2020-MSCA-IF-2015 - - - 704626 - - - - - Barcelonabeta Brain Research Center Foundation - - - EUR 158 121,60 - - - The effect of pro-aging and pro-youthful blood factors in normal ageing and Alzheimer’s disease: a multimodal approach - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - The overall aim of the planned research is to test whether pro-aging and pro-youthful blood factors are associated with cognitive performance and neuroimaging outcomes in normal ageing and in individuals at risk of Alzheimer’s - disease (AD), and whether this association is modified by lifestyle habits (e.g. exercise or diet) or genetic factors. Ageing is the most important risk factor for AD. However, the exact mechanism that link ageing and AD is still unknown and, up to - now, potential therapies for AD by targeting ageing have been poorly explored. Thus, in the present project we aim to provide a better understanding of the link between ageing and AD by measuring in human blood those factors that have been found to - be ‘pro-youthful’ (GDF-11) or ‘pro-aging’ (CCL2, CCL11 and CCL19) in experimental animal models, but have not been comprehensively studied in humans. For these purposes, we will first develop novel and highly specific and sensitive assays based on - the state-of-the-art Simoa platform. Next, we will measure these factors in the participants of the ALFA (Alzheimer and Families) study, which is currently taking place in the Barcelonaβeta Brain Research Centre (BBRC), the host institution of this - project. The ALFA cohort is composed of 2743 cognitively healthy individuals (45 to 75 years old) from which comprehensive clinical, neuropsychological, neuroimaging, genetic and environmental and lifestyle factors data are already available. - Measurements will be performed in two steps: a training cohort and a validation cohort. Finally, we will investigate the association of the levels of the pro-aging/pro-youthful blood factors with features known to be related to AD such as clinical - and life-style variables, neuroimaging outcomes and signatures and genetic variables. Altogether, the results of this project will clarify whether those blood pro-aging or pro-youthful factors may become potential therapeutic targets in AD. - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - BioALFA - - - H2020-MSCA-IF-2016 - - - 752310 - - - - - THE UNIVERSITY OF EDINBURGH - - - EUR 183 454,80 - - - Deep Biosignatures on Mars and Earth - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - "In recent decades, samples from mines and boreholes have revealed that our planet’s biosphere extends several miles downwards into the crust. Pores and fissures far below the seafloor and land surface are populated by vast - numbers of microorganisms, with broad economic and scientific implications. These implications reach as far as Mars, whose subsurface has provided a potentially habitable environment for billions of years, protected from the hostile conditions at the - surface. Although Earth's modern-day ""deep biosphere"" is now the subject of a major global research effort, almost nothing is known about its variation across geological time, which may have been considerable and highly consequential for planetary - biogeochemistry. This project will combine state-of-the-art analyses of fossil and chemical traces of deep life (""deep biosignatures"") with experimental and modelling work to elucidate the abundance, activity and geological record of ancient - subsurface life on Earth and its possible relevance for Mars. Dr McMahon’s research at the UK Centre for Astrobiology (School of Physics and Astronomy, University of Edinburgh) will be directed towards four main objectives, as follows: - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - D BIOME - - - H2020-MSCA-IF-2016 - - - 747877 - - - - - CONSIGLIO NAZIONALE DELLE RICERCHE - - - EUR 168 277,20 - - - Out-of-equilibrium nanophotonics - - - EUR 168 277,20 - - - Italy - - - Research Organisations - - OUTNANO is about developing a new generation of nanophotonic devices by exploiting ultrafast dynamics of electrons driven out-of-equilibrium. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - OUTNANO - - - H2020-MSCA-IF-2016 - - - 746774 - - - - - UNIVERSITEIT GENT - - - EUR 172 800 - - - Crowdsourcing Urban Sustainability Governance. Exploring innovative governance models for addressing urban sustainability through ICT-people interaction - - - EUR 172 800 - - - Belgium - - - Higher or Secondary Education Establishments - - The project explores the potential of crowdsourcing (an online, distributed problem-solving process for creative solutions - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Belgium - - - CROWD_USG - - - H2020-MSCA-IF-2016 - - - 740191 - - - - - EUROPEAN NETWORK ON INDEPENDENT LIVING BRUSSELS OFFICE - - - EUR 140 994 - - - USER-LED PERSONAL ASSISTANCE IN THE EUROPEAN UNION: A CRITICAL COMPARATIVE ANALYSIS - - - EUR 140 994 - - - Belgium - - - Other - - This research will compare and evaluate User-Led Personal Assistance (ULPA) schemes for disabled people across the European Union. ULPA schemes will be approached from the perspective of the Independent Living philosophy and - the social model of disability in order to evaluate their potential to equalise disabled peoples participation in social life. The research will be hosted by the European Network on Independent Living, a leading advocate for ULPA in Europe. Through - its membership network, the organisation will enable the researcher to seek advice and feedback from disabled people’s organisations, thus facilitating a participatory approach to research. The main outcomes will be a bespoke framework for normative - evaluation of ULPA and a collection of best practices in ULPA in the European Union. These outcomes will benefit disabled people, their organisations, practitioners and policy makers working on European disability policy. Overall, the research will - contribute to processes of European integration towards the building of barrier-free Europe for all. - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-SE - Society and Enterprise panel - - - Belgium - - - ULPA - - - H2020-MSCA-IF-2016 - - - 747027 - - - - - UNIVERSITE GRENOBLE ALPES - UNIVERSITE GRENOBLE ALPES - - - EUR 1 498 840 - - - The Neutron Electric Dipole Moment: pushing the precision to understand the matter-antimatter asymmetry - - - EUR 1 498 840 - - - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The existence of a permanent electric dipole moment (EDM) of the neutron, or any subatomic particle, would have far reaching implications connecting particle physics with cosmology. Time reversal invariance and CP symmetry - would be violated. A new fundamental interaction producing the EDM, that is, deforming the charge distribution inside the neutron, could also have generated the matter-antimatter asymmetry in the early Universe. After 60 years of evolution, - techniques to measure the neutron EDM are now so evolved that experiments are sensitive to microphysics associated with an energy scale beyond that accessible at the LHC. This situation offers a high likelihood of discovery for the next generation of - experiments. In the same time, any improvement in precision is technically challenging. The control of the magnetic field must surpass that of the state of the art of atomic magnetometers. The n2EDM project aims at improving the precision by an order - of magnitude or more. Systematic effects need to be controlled at an unprecedented level. In particular, the use of a mercury co-magnetometer based on the precession of 199Hg spins induces a set of subtle false effects due to the relativistic - motional field. - - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - France - - - NEDM - - - ERC-2016-STG - - - 716651 - - - - - DEUTSCHES KREBSFORSCHUNGSZENTRUM - DEUTSCHES KREBSFORSCHUNGSZENTRUM - KAROLINSKA INSTITUTET - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 2 270 000 - - - RNA EDITING IN HEALTH AND DISEASE - - - EUR 2 270 000 - - - Germany - Germany - Sweden - United Kingdom - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - "RNA editing is a type of programmed RNA sequence alteration that can result in a range of proteomic changes, from subtle fluctuations in output, to specific alterations in protein content. Editing is catalyzed by two classes - of deaminases: those which convert adenosine to inosine (ADARs) and those which convert cytosine to uracil (APOBEC1). We have previously shown that APOBEC1-catalyzed editing in the transcriptome of macrophages leads to the generation of populations - that are heterogeneous, and functionally diverse, enabling rapid population adaptation to different environmental settings. - - - 2020-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - RNAEDIT - - - ERC-2014-CoG - - - 649019 - - - - - NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA - UNIVERSITA DEGLI STUDI DELLA CAMPANIA LUIGI VANVITELLI - CRANFIELD UNIVERSITY - FYZIKALNY USTAV SLOVENSKEJ AKADEMIE VIED - EXIS INNOVATION LTD - - - EUR 2 578 386 - - - Hybrid Electric Energy Integrated Cluster concerning Renewable Fuels - - - EUR 2 578 386 - - - Greece - Italy - United Kingdom - Slovakia - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The targeted breakthrough of the HELENIC-REF project refers to the establishment of a new sustainable methodology for the water thermolysis at temperatures below 300oC and the immediate corresponding production of energy or - fuels. The method is based on our preliminary experimental evidence of water thermolysis at 286oC in the presence of Fe3O4 nanoporous catalytic thick films, with the sustainable maintenance of the catalyst due to a new reduction method based on - Lorentz force electrons generated by a magnetic field in the vicinity of the electric current heating the semiconducting catalyst. The method is used for the production of hydrogen and oxygen, as well as of fuels in the presence of CO2 in order to - reduce CO2 to CO or even to hydrocarbons, (like Synthetic Natural Gas – SNG) via methanation. - - 2018-05-31, ongoing project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-1-2014 - FET-Open research projects - - - RIA - Research and Innovation action - - - Greece - - - HELENIC-REF - - - H2020-FETOPEN-2014-2015-RIA - - - 665318 - - - - - UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA - UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA - QUEEN MARY UNIVERSITY OF LONDON - ISTITUTO NAZIONALE DI FISICA NUCLEARE - - - EUR 1 971 841 - - - Uncovering New Phenomena at the TeV Scale With Top Quarks - - - EUR 1 971 841 - - - Italy - Italy - United Kingdom - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - Our understanding of the subatomic world and of the very fabric of the space-time is encompassed in a theory which is the result of all past experimental observations and theoretical developments: the Standard Model of - Particle Physics. Yet cosmological observations and theoretical arguments lead us to conclude that new phenomenology, - - 2020-08-31, ongoing project | - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Italy - - - NPTEV-TQP2020 - - - ERC-2014-CoG - - - 648723 - - - - - TECHNISCHE UNIVERSITEIT DELFT - ALBERT-LUDWIGS-UNIVERSITAET FREIBURG - CHALMERS TEKNISKA HOEGSKOLA AB - KATHOLIEKE UNIVERSITEIT LEUVEN - TECHNISCHE UNIVERSITAET MUENCHEN - UNIVERSITY OF LIMERICK - AMPYX POWER BV - SKYSAILS GMBH - XSENS TECHNOLOGIES B.V. - ENERKITE GMBH - - - EUR 2 999 014,68 - - - Airborne Wind Energy System Modelling, Control and Optimisation - - - EUR 2 999 014,68 - - - Netherlands - Germany - Sweden - Belgium - Germany - Ireland - Netherlands - Germany - Netherlands - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The height of conventional wind turbines is limited by the enormous stresses on the structure. The idea of the Airborne Wind Energy (AWE) is to replace the most efficient part of a conventional wind turbine, the tip of the - turbine blade, with a fast flying high efficiency kite, and to replace the rest of the structure by a tether which anchors the kite to the ground. Power is generated either by periodically pulling a ground based generator via a winch, or by small - wind turbines mounted on the kite that exploit its fast cross wind motion. While the concept is highly promising, major academic and industrial research is still needed to achieve the performance required for industrial deployment. This can best be - done by innovative junior researchers in a closely cooperating consortium of academic and industrial partners. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Netherlands - - - AWESCO - - - H2020-MSCA-ITN-2014 - - - 642682 - - - - - FUNDACION CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III - FUNDACION CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III - - - EUR 1 861 910 - - - YOUNGatHEART: CARDIAC REJUVENATION BY EPIGENETIC REMODELLING - - - EUR 1 861 910 - - - Spain - Spain - - - Research Organisations - Research Organisations - - Aging poses the largest risk for cardiovascular disease (CVD) and is orchestrated, to some extent, by epigenetic changes. Despite the significant progress on many fronts in the cardiovascular field, non-inherited epigenetic - regulation in cardiac aging and CVD remains unexplored. Dilated Cardiomyopathy (DCM) is a major contributor to healthcare costs and it is the leading indication for heart transplantation. We have recently discovered that adult cardiac-specific - deletion of epigenetic regulator Bmi1 in mice induces DCM and heart failure. These unprecedented data support the idea that inadequate epigenetic regulation in adulthood is critical in CVD. In addition, our studies with parabiotic pairing of healthy - and DCM-diagnosed mice show that the circulation of a healthy mouse significantly improve the cardiac performance of mouse with DCM. These ground-breaking discoveries suggest that DCM regression, or cardiac rejuvenation, is feasible in terms of - epigenetic states. Therefore, YOUNGatHEART will unveil significant breakthrough on (1) how non-inherited epigenetic deregulation induces DCM and (2) how epigenetic remodeling reversed this process. For that, our challenges are: 1A. To decipher how - aged-linked cardiac dysfunction contributes to CVD by identifying the epigenetic landscape regulating cardiac aging among species; 1B. To decode how epigenetic deregulation induces DCM by integrating clinical data and samples from DCM-transplanted - patients with imaging, transcriptomic, proteomic, and functional approaches from DCM model; and, 2A. To identified systemic factors with anti-cardiomyopathic effects by systematic proteomic screenings after parabiosis and epigenome of the DCM hearts. - In sum, YOUNGatHEART puts forward an ambitious but feasible and pioneering program to tackle the epigenetic hallmark in cardiac aging with the final aim (2B) of setting the molecular basis for future therapeutic interventions in CVD. - - 2020-10-31, Grant Agreement terminated - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Spain - - - YOUNGatHEART - - - ERC-2014-CoG - - - 647670 - - - - - UNIVERSIDAD POMPEU FABRA - - - EUR 158 121,60 - - - Speech-sound Processing in Infant Development and Evolution - - - EUR 158 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - "What are the uniquely human mechanisms of language acquisition that enable infants to start discovering the words and structures of their native language by the end of their first year? Language is undoubtedly a specifically - human function, but it is crucial to disentangle between human-specific vs. general-processing skills that allow language acquisition. This project aims at exploring the developmental and evolutionary origins of one of the features of speech - processing: the ability to assign specific functional roles to the different categories of sounds composing speech. Indeed, there is a Consonant/Vowel functional asymmetry in the world's languages as well as in speech processing, whereby consonants - better fit the requirements of lexical processing (e.g. when writing abbreviations we tend to remove vowels and keep consonants to avoid compromising meaning, as in txt msgng), while vowels are better targets for syntax-related processes. It remains - unknown where this "division of labour" comes from: uniquely human predisposition playing a role in early syntax and lexical acquisition, or consequence of the asymmetry present in the input? - - - 2018-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - SPIDE - - - H2020-MSCA-IF-2015 - - - 707996 - - - - - UNIVERSITA CA' FOSCARI VENEZIA - - - EUR 168 277,20 - - - Ancient scholarship on archaic Greek iambic poetry - - - EUR 168 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - The proposed research concerns ancient scholarship on archaic Greek iambic poetry from the Hellenistic to the Byzantine period. It investigates the history of such scholarship in its various embodiments (editions, - commentaries, marginal annotations, monographs on individual topics, author- and genre-specific lexica, and others) and the aims, concerns, assumptions, and techniques that it deployed. This investigation - the first of its kind - aims to - contextualise such items of scholarship, and scholarship on iambos generally, within the broader picture of ancient literary scholarship. The study of ancient scholarship is a budding field, making the proposed research timely as well as necessary. - Ancient scholarship has long been among my research interests. Given the Department's strengths on archaic Greek poetry and ancient scholarship, and Ca' Foscari's commitment to fostering research and supporting young researchers' skills development, - Venice is the ideal partner for the success of the proposed research. Holding a Marie Sklodowska-Curie would be highly beneficial to my academic career and enable me to achieve independence as a professional researcher. - - 2018-10-02, ongoing project - - - 2016-10-03 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - ASAGIP - - - H2020-MSCA-IF-2015 - - - 708556 - - - - - DANMARKS TEKNISKE UNIVERSITET - UNIVERSITY OF KENT - DUBLIN CITY UNIVERSITY - ACIB GmbH - RENTSCHLER BIOTECHNOLOGIE GMBH - UCB PHARMA SA - - - EUR 4 044 793,68 - - - Enhancing CHO by Mammalian Systems Biotechnology (eCHO systems) - - - EUR 4 044 794,43 - - - Denmark - United Kingdom - Ireland - Austria - Germany - Belgium - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Chinese hamster (CHO) ovary cells are the production host for a +50 billion €/yr biopharmaceuticals market. Current CHO production platforms dates to 1980 and are based primarily on media and process optimisation with little - consideration to the optimization of the cellular machinery. Fortunately, with the recent sequencing of the CHO genome, an opportunity has opened to significantly advance the CHO platform. The benefit will be advanced production flexibility and a - lower production cost. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Denmark - - - eCHO Systems - - - H2020-MSCA-ITN-2014 - - - 642663 - - - - - UNIVERSIDAD POMPEU FABRA - - - EUR 170 121,60 - - - The Early Peopling of Amazonia and the Beginning of Plant Domestication - - - EUR 170 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - This project investigates two relevant, inter-related and multi-disciplinary topics in the prehistory of the Neotropic: 1) the social-ecological dynamics of earliest people of SW Amazonia and 2) the role these early Holocene - populations played in the domestication of Neotropical plants. Genetic studies suggest that SW Amazonia, and in particular the Llanos de Moxos in Bolivia, is a region where important Amazonian crops were domesticated, including manioc, peanut, peach - palm, jack bean and two varieties of chili pepper. However, genetic evidence has not been substantiated by archaeology as yet, due to the virtual absence of early sites in the region. The applicant’s recent discovery of early Holocene shell-middens - in the area and the application of state-of-the-art multi-proxy techniques offer a unique opportunity to provide archaeological evidence for plant exploitation trajectories. Six early sites, and their local environments, are going to be studied for - the first time through a focus on socio-ecological interactions and plant management strategies. The proposal is a fundamental step in the applicant’s career as he will be able to dramatically improve his technical skills in several archaeological - techniques (phytoliths, starch, micromorphology, shell middens excavation). The research will also enhance the candidate's capabilities to integrate palaeoecological and archaeological evidence, a decisive move to promote his scientific leadership - and career development. - - 2018-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - EPP-Am - - - H2020-MSCA-IF-2015 - - - 703045 - - - - - KUNGLIGA TEKNISKA HOEGSKOLAN - - - EUR 173 857,20 - - - Single-Photon Non-Locality - - - EUR 173 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - The principle of non-locality is one of the most impressive features of quantum mechanics. Usually, non-locality is related to two or more particles sharing a common characteristic. This quantum mechanical effect is well - understood and several experimental demonstrations have been performed. However, non-locality of a single particle, in particular of a single-photon raises fundamental questions: Can a single-photon be simultaneously at different locations? In spite - of numerous theoretical concepts, no clear experiment has yet been reported. - - 2017-10-31, closed project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - SiPhoN - - - H2020-MSCA-IF-2014 - - - 661416 - - - - - BEN-GURION UNIVERSITY OF THE NEGEV - BEN-GURION UNIVERSITY OF THE NEGEV - - - EUR 1 303 750 - - - Combinatorial Aspects of Computational Geometry - - - EUR 1 303 750 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The project focuses on the interface between computational and combinatorial geometry. - - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Israel - - - CombiCompGeom - - - ERC-2015-STG - - - 678765 - - - - - UNIVERSIDAD POMPEU FABRA - - - EUR 158 121,60 - - - Global Policy Uncertainty and International Asset Markets - - - EUR 158 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - Government policies - fiscal, monetary, and regulatory - define the rules of the game for economic agents. However, uncertainty about policy changes may affect the economy adversely as it acts as an additional source of risk. - In an interconnected world economy, policy uncertainty has spillover effects beyond national borders, and becomes a global source of risk. In this context, this project investigates the relationship between global policy uncertainty - the common - driver of uncertainty across countries - and international financial markets. In the aftermath of the financial crisis, it is timely and relevant to deepen our understanding of these relationships. This may, in turn, inform the development of - policies that minimize the adverse impacts of uncertainty, particularly in regions of high economic integration as the Euro zone. - - - 2018-09-21, ongoing project - - - 2016-09-22 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - GlobalPolicyUncertainty - - - H2020-MSCA-IF-2015 - - - 705686 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 170 121,60 - - - Direct and indirect effects of Climate Change on biotic communities and exotic Pathogens in mixed Mediterranean forests - - - EUR 170 121,60 - - - Spain - - - Research Organisations - - Global change is a complex phenomenon that involves several factors such as climate change, the alteration of the nitrogen cycle, biological invasions or changes in land use. Although each of these factors has been - individually studied in detail in the last years, it is still poorly known how they could interact to affect biotic communities and the ecosystem processes that they control. The general objective of this proposal is to advance in the understanding - of the direct and indirect effects of climate change on biotic communities and invasive pathogens interactions in forest systems. This interaction has been largely ignored so far, but its consideration is crucial to understand how abiotic and biotic - stress factors together determine forest health and stability. Specifically, CCPaMe aims to: 1) Determine the direct effects of climate change on the exotic pathogen Phytophthora cinnamomi. It will be identified potential non-additive effects of - rainfall exclusion and warming on its abundance and infected capacity by field and growth chamber experiments. 2) Determine the indirect effects of climate change on soil microorganisms and P. cinnamomi ecology. It will be determined the effects of - climate change on the hosts susceptibility to P. cinnamomi and on the abundance, diversity and composition of soil organisms community (bacteria, fungi, archaea and actinomycete) and their implications for P. cinnamomi functionality: modification of - its infective capacity and the alteration of pathogen interactions with other soil microbes. CCPaMe results will provide key insights to address current challenges regarding climate change effects and exotic pathogen control on forest systems and the - conservation and protection of forest resources. Moreover, they will allow an improvement of our predictive capacity of the socio-economic consequences of future P. cinnamomi outbreaks, serving as a guide for the design of up-to-date management and - mitigation policies. - - 2018-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - CCPaMe - - - H2020-MSCA-IF-2015 - - - 706055 - - - - - UNIVERSITY OF KENT - - - EUR 195 454,80 - - - Evolution of the Ape Forelimb: Evidence from Internal Bone Structure - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - "Understanding the locomotor behaviour of our Miocene ape ancestors is critical to reconstructing the evolution of walking on two feet, or bipedalism. The Miocene (20-5 million years ago (Ma)) epoch is crucial because it is - during this period that the morphological features of living great apes, including humans, were defined. In this respect, Miocene apes show unique morphological combinations that are unlike any living primate, known as "mosaic morphologies", which - include derived (ape-like) and primitive (generalised) features more suitable to provide a model from which bipedal fossil humans (hominins) – our direct ancestors – might have evolved. This project uses novel 3D methods (microCT scans and imaging - sotfware) to conduct the first holistic analysis of the internal structure of Miocene ape forelimb bones. Bone remodels throughout life in response to load; variation in internal structure thus correlates with forelimb use and offers a more direct - window into behaviour than external morphology alone. The bony joints of the forelimb on an array of extant Primate species, including apes and monkeys, will be analysed, shedding new light on Miocene ape locomotion, the evolution of living apes and - the emergence of human bipedalism." - - 2018-05-31, ongoing project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - MOSAIC - - - H2020-MSCA-IF-2015 - - - 703608 - - - - - UNIVERSITY OF GLASGOW - - - EUR 183 454,80 - - - Understanding the light-fastness of heritage Turkey Red textiles through modern dye chemistry and historical dyeing technology to inform sustainable display and access - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - LightFasTR seeks to increase physical and creative access to Europe’s most profitable globalised textile of the 19th c. Industrial Revolution - Turkey red (TR) printed cotton. TR was famed for colourful bold patterns on a - characteristic bright red background. Many 19th c. TR printed cottons survive within the pages of pattern books as well-preserved, vibrant and creative storyboards of forgotten global trade and cultural connections. Museums and archives want to - exhibit these collections and increase access, but need to preserve the colours, especially the characteristic red. The 19th c. TR makers’ claim of excellent light-fastness for the red dye is unproven, raising uncertainty about suitable light levels - and exposure times for historical TR textile collections. LightFasTR unites the materials and processes of making 19th c. TR with modern dye chemistry and heritage textile conservation science to provide essential guidance for museums and archives. - - - 2019-03-19, ongoing project - - - 2017-03-20 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - LightFasTR - - - H2020-MSCA-IF-2015 - - - 708740 - - - - - BEN-GURION UNIVERSITY OF THE NEGEV - BEN-GURION UNIVERSITY OF THE NEGEV - - - EUR 1 625 000 - - - Quantitative Nanoscale Visualization of Macromolecular Complexes in Live Cells using Genetic Code Expansion and High-Resolution Imaging - - - EUR 1 625 000 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - High-resolution fluorescence imaging, including super-resolution microscopy and high-speed live cell imaging, are used to obtain quantitative information on the structural organization and kinetics of cellular processes. The - contribution of these high-resolution techniques to cell biology was recently demonstrated for dynamin- and ESCRT-driven membrane fission in cells. While they advance our knowledge on membrane fission these techniques do not provide the quantitative - information needed to formulate a mechanical understanding of membrane fission in a physiological context, a shortcoming that stresses the need to increase the spatiotemporal resolution and improve the live cell capabilities of these techniques. - Substituting the bulky fluorescent protein tags (such as GFP) currently used in live-cell applications with much smaller fluorescent dyes that possess superior photophysical characteristics will markedly improve these advanced imaging techniques. - Genetic code expansion and bioorthogonal labeling offer, for the first time, a non-invasive way to specifically attach such fluorescent dyes to proteins in live cells. I, therefore, propose to develop an innovative approach to label cellular proteins - with fluorescent dyes via genetic code expansion for quantitative high-resolution live cell imaging of cellular protein complexes. By applying this approach to three distinguished high-resolution methodologies and by visualizing membrane fission in - distinct cellular processes in live cells at milliseconds rate and at nanoscale resolution, we aim to decipher the mechanistic principles of membrane fission in cells. As numerous cellular processes rely on membrane fission for their function, such - an understanding will have a broad impact on cell biology. The implications of this study reach beyond the scope of membrane fission by offering a new approach to study cellular processes at close-to-real conditions in live cells and at nanoscale - resolution. - - 2020-03-31, ongoing project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Israel - - - VisuLive - - - ERC-2014-STG - - - 639313 - - - - - KUNGLIGA TEKNISKA HOEGSKOLAN - - - EUR 185 857,20 - - - Green and robust approaches towards dual-purpose dendritic adhesives: Novel minimally invasive methodologies for bone fracture fixation applications - - - EUR 185 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - A vast number of human bone fractures rely on screw-fixated metal implants. While being effective, their rigid design, combined with open surgical conditions and general anesthesiology, make them poor candidates for thin or - fragile bones, such as those that might be found in the elderly population. The proposal is intended to identify a minimally invasive surgical concept, based on novel bone adhesives (glues) for treatment of complicated bone fractures, under local - anesthesia. This will be accomplished by developing a library comprised of a dendritic scaffold, a cross-linker and a fibre component. Upon mixing, the dendritic component is programmed to efficiently adhere to wet bone surfaces and on-demand react - with the cross-linker to form a bone adhesive patch (BAP). The fibre component is embedded to produce BAPs covering a range of load bearing properties. - - 2017-07-31, closed project - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - DendroBAP - - - H2020-MSCA-IF-2014 - - - 655649 - - - - - BEN-GURION UNIVERSITY OF THE NEGEV - BEN-GURION UNIVERSITY OF THE NEGEV - - - EUR 1 499 000 - - - The Plasmidome: a Driving Force of Rumen Microbial Evolution from Birth to Adulthood - - - EUR 1 499 000 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Plasmids are known to be major contributors to lateral gene transfer in bacterial genomes; however, their comprehensive evolutionary role within bacterial communities is poorly understood. Recently we have developed cutting - edge abilities to access a plasmid population (plasmidome) of a given microbial community, and applied them to rumen microbial communities. These abilities are an element long-needed for the study of microbial lateral gene transfer and evolution. - Ruminants house a highly complex microbial community in the rumen compartment of their digestive tract, with which they have evolved into an obligatory co-dependence. Its confined nature provides a perfect system for the study of evolutionary - dynamics within microbial communities. - - 2020-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Israel - - - RuMicroPlas - - - ERC-2014-STG - - - 640384 - - - - - STOCKHOLMS UNIVERSITET - STOCKHOLMS UNIVERSITET - - - EUR 1 969 599 - - - Towards middle-range theories of the co-evolutionary dynamics of multi-level social-ecological systems - - - EUR 1 969 599 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Humans have the capacity to change the biosphere from local to global scales while at the same time fundamentally depending on a functioning biosphere for their well-being. Moreover human societies are increasingly affected by - global change and adapting to it in multiple ways. These interdependencies give rise to non-linear, cross-scale dynamics that pose significant challenges for analysis and governance of social-ecological systems (SES). In view of the need for societal - transformations towards sustainability is the identification of mechanisms of change in SES an urgent and cutting-edge research frontier. This project aims to develop new methodologies and middle-range theories of the dynamics of SES. It will take - the nature of SES as complex adaptive systems into account by developing a mechanism-based understanding of change in SES as it arises from micro-level interactions within complex networks of actors and ecosystems. Particular emphasis will be put on - emergent and top-down cross-scale interactions. - - - 2022-01-31, ongoing project - - - 2017-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Sweden - - - MUSES - - - ERC-2015-CoG - - - 682472 - - - - - UNIVERSIDAD POMPEU FABRA - UNIVERSIDAD POMPEU FABRA - - - EUR 1 170 625 - - - Social Media, Political Participation, and Accountability - - - EUR 1 170 625 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The goal of the project is to examine how advances in information technologies affect public policies. In particular, it will empirically investigate the causal effect of social media on political participation. The first part - of the project will examine the effect of social media penetration on participation in political protest activities, as well as the mechanisms that drive these effects, using a specific example of protests activities in Russia in 2011-2012. We will - exploit idiosyncratic variation in the early penetration of social media across cities to identify causal effect of social media penetration on participation in protest activities. We will also exploit the effects of early penetration on the - distribution of users across competing online social networks to examine the role of coordination as a specific mechanism behind the effect. The second part of the project will use content analysis of the messages in social media and detailed - information on the network structure and its evolution over time to study (1) the effect of network structure on the diffusion of information and subsequent actions; (2) the effect of offline events on network formation. Exogenous shock in the form - of unexpected wave of protest activities will be used to identify the effects of interest. Smaller parts of the project will use survey experiments and cross-country comparison of the content of traditional and social media to provide additional - evidence on the mechanisms behind the effects of social media. The project will be mainly empirical, but it will rely heavily on the theoretical advances in the fields of political economy and network analysis. - - 2020-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Spain - - - SocialMedia - - - ERC-2014-STG - - - 638221 - - - - - UNIVERSIDAD POMPEU FABRA - UNIVERSIDAD POMPEU FABRA - - - EUR 1 699 664 - - - HISTORICAL ROOTS OF CONFLICT AND DEVELOPMENT: FROM PREHISTORY TO THE COLONIZATION EXPERIENCE - - - EUR 1 699 664 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - I plan to study the effect of history on conflict and economic development with two historical microscopes. - - 2020-04-30, ongoing project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Spain - - - HISTROOTS - - - ERC-2014-CoG - - - 647514 - - - - - UNIVERSIDAD POMPEU FABRA - UNIVERSIDAD POMPEU FABRA - - - EUR 1 308 676 - - - Debt and Persistence of Financial Shocks - - - EUR 1 308 676 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In 2007 the US and Europe were overwhelmed by a banking crisis, which was followed by a severe economic recession. Historical studies show that financial crises are followed by periods of substantially stronger contraction of - aggregate output and employment than non-financial recessions. Those studies also point out that the best predictor of financial crises is an ex-ante strong credit boom which, after the beginning of the crisis, followed by negative overall credit - growth. Lastly, financial crises take a long time until recovering the pre-crisis levels. - - - 2020-06-30, ongoing project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Spain - - - PERSISTDEBT - - - ERC-2014-CoG - - - 648398 - - - - - HELMHOLTZ ZENTRUM POTSDAM DEUTSCHESGEOFORSCHUNGSZENTRUM GFZ - - - EUR 171 460,80 - - - Silica and alumina nanophases – the building blocks for the ground under our feet. - - - EUR 171 460,80 - - - Germany - - - Research Organisations - - Alumina and silica nanophases play a crucial role in rock weathering and their formation and destruction controls Earth’s response to global climate change. The presence of various products of aqueous weathering of - aluminosilicates points to a complex activity of water, and is considered as the geological indication for the occurrence of life-habitable conditions. In this regard, a more complete picture of the water-alumina-silica interactions would allow for - better specifying the molecular-level conditions for early life. Upon weathering the original Al- and Si-containing phases are dissolved at the solid-water interface, undergo hydrolysis and condensation reactions and form new colloidal nanoparticles. - However, quantitative and mechanistic understanding of the underlying processes that lead to the formation and types of Al and Si phases is still lacking, due to the insufficient in situ methodology providing structural information about the - colloidal species in solution. - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - NanoSiAl - - - H2020-MSCA-IF-2015 - - - 703015 - - - - - UNIVERSITAT WIEN - - - EUR 178 156,80 - - - Transnational nationalism. Far-Right Nationalist Groups in East Central Europe in the 20th and 21st centuries - - - EUR 178 156,80 - - - Austria - - - Higher or Secondary Education Establishments - - The project will study networks of youth far-right nationalist organizations in East Central Europe, paying particular attention to the developments in Austria, Croatia, Hungary, and Poland. Using historical and - anthropological methods, the study explores the transnational dimension of nationalist organizations: the networking of ideologies and tactics. It entails a combination of archival research, interviews, and participant observation during nationalist - gatherings. In proposing a historical-ethnographic study of youth far-right nationalist groups, the project aims to fill the gap in existing scholarship, resulting from the lack of interdisciplinary dialogue, negligence of a historical dimension, and - macro-perspective predominance. Inspired by the transnational history approach, it foregrounds the complex – synchronic and diachronic - interactions between European nationalisms and studies agents of those exchanges, examining nationalist - activists’ motivations and experiences. A combination of anthropological in-depth analysis and historical approach offers an original perspective by drawing parallels between nationalist activities against a multinational federative system, the - Austro-Hungarian Empire, and the EU. It provides a critical tool for challenging unidirectional models of modernity and nationalism and for reflecting on the challenges to the European integration. - - 2017-09-30, closed project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Austria - - - Transnat_farright - - - H2020-MSCA-IF-2014 - - - 656377 - - - - - UNIVERSIDAD POMPEU FABRA - UNIVERSIDAD POMPEU FABRA - - - EUR 1 876 846 - - - Post-Cellular Wireless Networks - - - EUR 1 876 846 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - POSTCELL aims at laying the foundation for future generations of wireless networks as they move past the reigning cell-centric paradigm and into the post-cellular era. This entails the definition of a new architecture for such - networks and the characterization of the ensuing performance. For the future of wireless communications, the implications would be far-reaching. - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Spain - - - POSTCELL - - - ERC-2015-AdG - - - 694974 - - - - - HASKOLI ISLANDS - STOCKHOLMS UNIVERSITET - UNIVERSITE CLERMONT AUVERGNE - UNIVERSITE BLAISE PASCAL CLERMONT-FERRAND II - - - EUR 3 182 721,12 - - - Adaptation to a New Economic Reality - - - EUR 3 182 721,12 - - - Iceland - Sweden - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The present economic model of permanent growth is unstable and leads to cycles of growth, peaks and crashes. We propose to contribute to developing new economic thinking based on knowledge of global resources availability. The - Adaptation to a New Economic Reality (AdaptEconII) project is divided into three parts: 1. Sustainable resource management; 2. Integrated economic systems assessment; and 3. Integrating society and economics. These components will be combined to form - an overarching economic model built on socio-environmental-technical (SET) system analysis of causal links and feedback structures and system dynamics. A simple prototype of such a model (WORLD) has already been built by the applicants and tested on - historical data. Twelve Early Stage Researchers (ESRs) will be trained to obtain European Joint Doctorates at three universities: University of Iceland (Reykjavik, Iceland), Stockholm University (Sweden) and Universite Blaise Pascal, Clermont-Ferrand - (France). The ESRs will have secondments in research institutes/NGOs/SMEs in Germany (GWS and Wuppertal Institute), UK (New Economics Foundation and Schumacher Institute) and Sweden (Swedish National Defense College). All of the ESRs will have a - career plan and be trained in system analysis and system dynamics in addition to conventional and biophysical economic paradigms. They will be presented with aspects of resource availability, links between resources and wealth, the rise of new and/or - rediscovered values and realization of our interdependent world, new development paradigms, political and industrial ecology, as well as science for sustainable society and transferable skills. AdaptEconII will train ESRs in new economic thinking and - the goal is for them be at the forefront of innovative economic thinking in the EU and the world. - - 2019-11-30, ongoing project - - - 2015-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-EJD - Marie Skłodowska-Curie Innovative Training Networks (ITN-EJD) - - - MSCA-ITN-EJD - European Joint Doctorates - - - Iceland - - - AdaptEconII - - - H2020-MSCA-ITN-2015 - - - 675153 - - - - - BEN-GURION UNIVERSITY OF THE NEGEV - BEN-GURION UNIVERSITY OF THE NEGEV - - - EUR 1 499 375 - - - Unravelling the role of lysine acetylation in the regulation of glycolysis in cancer cells through the development of synthetic biology-based tools - - - EUR 1 499 375 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Synthetic biology is an emerging discipline that offers powerful tools to control and manipulate fundamental processes in living matter. We propose to develop and apply such tools to modify the genetic code of cultured - mammalian cells and bacteria with the aim to study the role of lysine acetylation in the regulation of metabolism and in cancer development. Thousands of lysine acetylation sites were recently discovered on non-histone proteins, suggesting that - acetylation is a widespread and evolutionarily conserved post translational modification, similar in scope to phosphorylation and ubiquitination. Specifically, it has been found that most of the enzymes of metabolic processes—including glycolysis—are - acetylated, implying that acetylation is key regulator of cellular metabolism in general and in glycolysis in particular. The regulation of metabolic pathways is of particular importance to cancer research, as misregulation of metabolic pathways, - especially upregulation of glycolysis, is common to most transformed cells and is now considered a new hallmark of cancer. These data raise an immediate question: what is the role of acetylation in the regulation of glycolysis and in the metabolic - reprogramming of cancer cells? While current methods rely on mutational analyses, we will genetically encode the incorporation of acetylated lysine and directly measure the functional role of each acetylation site in cancerous and non-cancerous cell - lines. Using this methodology, we will study the structural and functional implications of all the acetylation sites in glycolytic enzymes. We will also decipher the mechanism by which acetylation is regulated by deacetylases and answer a long - standing question – how 18 deacetylases recognise their substrates among thousands of acetylated proteins? The developed methodologies can be applied to a wide range of protein families known to be acetylated, thereby making this study relevant to - diverse research fields. - - 2021-06-30, ongoing project - - - 2016-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Israel - - - AcetyLys - - - ERC-2015-STG - - - 678461 - - - - - KUNGLIGA TEKNISKA HOEGSKOLAN - - - EUR 173 857,20 - - - Nature-inspired control of turbulent flows - - - EUR 173 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - Many aspects of the animal flight still remain unexplored, despite the enormous possibilities they offer to improve the current aerospace technology. One such aspect that received least attention of the scientists is the - following: the wing surfaces of the flying animals are coated with hairs, feathers and other filamentous structures. These self-adaptive hairy layers strongly influence the flow field characteristics, and it has been reported that such coatings may - be used to control the laminar-turbulent transition as well as turbulence in order to achieve energy efficient flight. The objectives of the NiCoFlow project are: (1) to devise the essential mathematical and computational framework to study the flow - around objects with surface-mounted self-adaptive hairs, and (2) to elucidate the fundamental fluid dynamic mechanisms through which the surface coatings can enable new flow control strategies. In this work, a homogenized poro-elastic continuum - models will be used to describe the flow through the hairy layers. Moreover, a computational approach to simulate two-way coupling between such homogenized continuum models and the surrounding fluid flow will be developed.. This approach will be - thoroughly validated by simulating fluid flow over a flat plate attached with surface-mounted flexible hairs and comparing the numerical results against existing experimental data. The validated model will be used to perform direct numerical - simulations of transitional and turbulent flows to reveal the detailed flow characteristics, and shed light on how these self-adaptive hairy features may delay the transition to turbulence and reduce the turbulent skin-friction. A potential passive - control technique, relying on these nature-inspired hairy coatings, will have a large industrial impact, including applications in aeronautics, energy harvesting and the transport sector. - - 2018-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - NiCoFlow - - - H2020-MSCA-IF-2015 - - - 708281 - - - - - STOCKHOLMS UNIVERSITET - STOCKHOLMS UNIVERSITET - - - EUR 2 499 756 - - - Cryosphere-Carbon on Top of the Earth (CC-Top):Decreasing Uncertainties of Thawing Permafrost and Collapsing Methane Hydrates in the Arctic - - - EUR 2 499 756 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The enormous quantities of frozen carbon in the Arctic, held in shallow soils and sediments, act as “capacitors” of the global carbon system. Thawing permafrost (PF) and collapsing methane hydrates are top candidates to cause - a net transfer of carbon from land/ocean to the atmosphere this century, yet uncertainties abound. - - - 2021-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Sweden - - - CC-TOP - - - ERC-2015-AdG - - - 695331 - - - - - STOCKHOLMS UNIVERSITET - STOCKHOLMS UNIVERSITET - - - EUR 1 104 812 - - - Social and Political Economics: Theory and Evidence - - - EUR 1 104 812 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In this project, I will study how individual and social motives interact to drive individual decisions, a question that has fallen between the cracks of different social-science approaches. I will use a common theoretical - framework to approach an important, but badly understood, general question: do social motives reinforce or weaken the effect of changes in individual motives? By modifying this common framework to different applications, I will consider its - predictions empirically in different large data sets with individual-level information. The planned applications include four subprojects in the social, political, and economic spheres: (i) decisions in China on the ethnicity of children in - interethnic marriages and matching into such marriages, (ii) decisions on tax evasion in the U.K. and Sweden, (iii) decisions to give political campaign contributions in the U.S., and (iv) decisions about fertility in Sweden. I may also spell out the - common lessons from the results on the interaction between individual and social motives in monograph format intended for a broader audience. - - 2021-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Sweden - - - ECOSOCPOL - - - ERC-2015-AdG - - - 693402 - - - - - UNIVERSITY OF KENT - UNIVERSITY OF KENT - - - EUR 1 488 028 - - - Tracking the cognitive basis of social communication across the life-span - - - EUR 1 488 028 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - A vital part of successful everyday social interaction is the ability to infer information about others (e.g. their emotions, visual perspective, and language). Development of these social skills (termed Theory of Mind, ToM) - has been linked to improvements in more general cognitive skills, called Executive Functions (EF). However, to date very little is known of how this link varies with advancing age, and no model exists to explain the relationship. Thus, the key aim of - the proposed research is to systematically explore the cognitive basis of social communication and how this changes across the life-span. The research will address three complementary objectives: (1) to what degree can variations in ToM ability - across the life-span be accounted for by changes in EF skills, (2) how do ToM ability and EF skill change over time in different age groups (using longitudinal methods, i.e. test-retest of the same participants), and (3) can ToM ability be enhanced - through training specific EF skills, and how do these training effects differ across the life-span. Contrary to traditional studies of social communication, I will employ an interdisciplinary approach that links theory and practice from cognitive, - social, developmental, and clinical (neuro)psychology to study the relationship between ToM and EF across a broad and dynamic age range (10 to 80+ yrs old). I will use cutting-edge combinations of techniques (eye-tracking and EEG) and paradigms, - alongside sophisticated statistical methods to track the timecourse of social understanding, and model how it relates to EF and more general cognitive/social skills (eg. IQ, language) within and between individuals. This research will open up new - horizons in ToM research by developing an intervention programme to enhance the quality of social communication in older adults (thus improving their mental health and well-being), which has the potential to be applied in other individuals with - social communication deficits (eg. autism). - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - CogSoCoAGE - - - ERC-2014-STG - - - 636458 - - - - - UNIVERSIDAD POMPEU FABRA - UNIVERSIDAD POMPEU FABRA - - - EUR 282 874,96 - - - Support to the Vice-Presidents of the ERC Scientific Council 2016 - - - EUR 282 874,96 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Support to the Vice-Presidents of the ERC Scientific Council 2016 - - 2016-12-31, closed project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC - European Research Council - - - CSA - Coordination and support action - - - Spain - - - ERCSC-VPRES-SUP2016 - - - H2020-Adhoc-2014-20 - - - 721182 - - - - - UNIVERSITAET INNSBRUCK - FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG - THE QUEEN'S UNIVERSITY OF BELFAST - KUNGLIGA TEKNISKA HOEGSKOLAN - NUMERICAL MECHANICS APPLICATIONS INTERNATIONAL SA - IBM IRELAND LIMITED - - - EUR 3 366 196 - - - An Exascale Programming, Multi-objective Optimisation and Resilience Management Environment Based on Nested Recursive Parallelism - - - EUR 3 366 196 - - - Austria - Germany - United Kingdom - Sweden - Belgium - Ireland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Extreme scale HPC systems impose significant challenges for developers aiming at obtaining applications efficiently utilising all available resources. In particular, the development of such applications is accompanied by the - complex and labour-intensive task of managing parallel control flows, data dependencies and underlying hardware resources – each of these obligations constituting challenging problems on its own. The AllScale environment, the focus of this project, - will provide a novel, sophisticated approach enabling the decoupling of the specification of parallelism from the associated management activities during program execution. Its foundation is a parallel programming model based on nested recursive - parallelism, opening up the potential for a variety of compiler and runtime system based techniques adding to the capabilities of resulting applications. These include the (i) automated porting of application from small- to extreme scale - architectures, (ii) the flexible tuning of the program execution to satisfy trade-offs among multiple objectives including execution time, energy and resource usage, (iii) the management of hardware resources and associated parameters (e.g. clock - speed), (iv) the integration of resilience management measures to compensate for isolated hardware failures and (v) the possibility of online performance monitoring and analysis. All these services will be provided in an application independent, - reusable fashion by a combination of sophisticated, modular, and customizable compiler and runtime system based solutions. - - 2018-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.2."> - - - FETHPC-1-2014 - HPC Core Technologies, Programming Environments and Algorithms for Extreme Parallelism and Extreme Data Applications - - - RIA - Research and Innovation action - - - Austria - - - ALLScale - - - H2020-FETHPC-2014 - - - 671603 - - - - - UNIVERSITY OF YORK - STOCKHOLMS UNIVERSITET - KOBENHAVNS UNIVERSITET - RIJKSUNIVERSITEIT GRONINGEN - - - EUR 4 074 239,16 - - - Archaeology on the Edge: Northern Europe and the Circumpolar World - - - EUR 4 074 239,16 - - - United Kingdom - Sweden - Denmark - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - ArchSci2020 will provide structured state-of-the-art doctoral training to the next generation of archaeologists and biomolecular scientists forging a new generation of biomolecular archaeologists. Few other academic - disciplines have been so transformed in the last decade as Archaeology. ArchSci2020 meet the need of a new generation of researchers. International, intersectoral and interdisciplinary training will equip its early-stage researchers (ESRs) with - specific research-related and transferable skills, in order to provide enhanced career prospects across academia, industry and the third sector. The proposed ArchSci2020 network will bring together four leading research clusters each with - complementary expertise to deliver an integrated, flexible training package that will provide a sound basis for academic independence and preparation for vocations in the archaeology, heritage and beyond. ArchSci2020 will combine (i) a common - purpose, (ii) an unconditional commitment to the student experience, (iii) a pro-active stance towards international, inter-institutional research support and interdisciplinary study, (iv) a simple but effective management structure provided by a - Management Team, Supervisory Committee and the Work Package leaders, (v) and an established academic infrastructure and reputation. - - 2020-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-EJD - Marie Skłodowska-Curie Innovative Training Networks (ITN-EJD) - - - MSCA-ITN-EJD - European Joint Doctorates - - - United Kingdom - - - ArchSci2020 - - - H2020-MSCA-ITN-2015 - - - 676154 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSITAT POLITECNICA DE CATALUNYA - UNIVERSITY OF YORK - TECHNISCHE UNIVERSITAET KAISERSLAUTERN - NEC EUROPE LTD - EDUCATIONAL OTE AE - IQUADRAT INFORMATICA SL - FASMETRICS YPIRESIES KAI PROIONTA ILEKTROMAGNITIKON PEDION ANONYMI ETAIREIA - - - EUR 3 545 458,56 - - - Application-aware User-centric Programmable Architectures for 5G Multi-tenant Networks - - - EUR 3 545 458,56 - - - France - Spain - United Kingdom - Germany - United Kingdom - Greece - Spain - Greece - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The vision of future 5G networks encompasses a heterogeneous communication landscape in which existing Radio Access Technologies (RATs) will be integrated with evolving wireless technologies and systems, software-design - network architectures and cloud-enabled services. Effectively harnessing the potential of all these innovative and heterogeneous features and providing a programmable multi-tenant network architectural framework will be the key to the success of 5G, - and will be the main objective of the 5G-AURA project. Instead of focusing separately on the optimization of the diverse technological and architectural components, our efforts will be concentrated on providing a unifying framework that will sustain - the coexistence and coordination of networking, software and cloud technologies, ensure network programmability and efficient resource orchestration, minimize control and signalling overhead, support multi-tenancy and scalability, and promote the - development of new business models for emerging services. To efficiently achieve these objectives, 5G-AURA has identified 12 specific research challenges which have been mapped to 14 individual projects that will be carried out by 14 recruited ESRs. - The project’s consortium, formed by four academic institutions and four industrial partners, has the necessary expertise and available infrastructures to form a high quality training network across multiple disciplines, sectors and countries. - Considering that 5G is currently in an early development state and there are multiple open issues on 5G protocols, network architectures and technologies and standardization efforts, the timing of 5G-AURA is perfect, and the project has a strong - potential to have significant impact on academia and industry and enhance the European innovation capacity in terms of technical contributions, intersectoral training of scientists and professional and novel business opportunities. - - 2019-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - France - - - 5G-AURA - - - H2020-MSCA-ITN-2015 - - - 675806 - - - - - KUNGLIGA TEKNISKA HOEGSKOLAN - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - UNIVERSITY OF SOUTHAMPTON - THE UNIVERSITY OF EDINBURGH - UNIVERSITAET STUTTGART - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - MCLAREN RACING LIMITED - AUTOMOTIVE SIMULATION CENTER STUTTGART EV - - - EUR 3 312 235 - - - Enabling Exascale Fluid Dynamics Simulations - - - EUR 3 312 235 - - - Sweden - United Kingdom - United Kingdom - United Kingdom - Germany - Switzerland - United Kingdom - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - - We are surrounded by moving fluids (gases and liquids), be it during breathing or the blood flowing in arteries; the flow around cars, ships, and airplanes; the changes in cloud formations or the plankton transport in oceans; - even the formation of stars and galaxies are closely modeled as phenomena in fluid dynamics. Fluid Dynamics (FD) simulations provide a powerful tool for the analysis of such fluid flows and are an essential element of many industrial and academic - problems. - - 2018-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.2."> - - - FETHPC-1-2014 - HPC Core Technologies, Programming Environments and Algorithms for Extreme Parallelism and Extreme Data Applications - - - RIA - Research and Innovation action - - - Sweden - - - ExaFLOW - - - H2020-FETHPC-2014 - - - 671571 - - - - - KUNGLIGA TEKNISKA HOEGSKOLAN - KUNGLIGA TEKNISKA HOEGSKOLAN - - - EUR 150 000 - - - Minimal invasive x-ray source enabled by a novel vacuum packaging technique - - - EUR 150 000 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In this project we aim to demonstrate and test a MEMS-based miniaturized electronic x-ray source enabled through a vacuum packaging concept developed under an ERC AdG. The source should be capable of delivering doses up to - approximately 1 Gy/min at a 2 mm distance while still having a millimetre overall size. This will be achieved by combining the vacuum packaging technique with a pointed field emission array developed in another project. The goal of the project is to - demonstrate key functionalities and take the technology to TRL 4 with the ambition establish collaboration with leading company in brachytherapy. - - 2015-12-31, closed project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2014 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Sweden - - - xMEMSRAY - - - ERC-2014-PoC - - - 641386 - - - - - TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY - WEIZMANN INSTITUTE OF SCIENCE - EUROPEAN MOLECULAR BIOLOGY LABORATORY - IMPASARA LIMITED - AGILENT TECHNOLOGIES LDA ISRAEL LTD - KAROLINSKA INSTITUTET - GENOME RESEARCH LIMITED - - - EUR 3 999 661 - - - Massive Reverse Genomics to Decipher Gene Regulatory Grammar - - - EUR 3 999 661 - - - Israel - Israel - Germany - United Kingdom - Israel - Sweden - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - - MRG-GRammar aims to devise an entirely new strategy for deciphering the regulatory rules of gene regulation. We will leverage Synthetic Biology with cutting-edge DNA synthesis technologies and high-throughput analysis to - generate new types of biological datasets that systematically explore all possible regulatory landscapes rather than just the naturally occurring regulatory sequences. - - 2018-07-31, ongoing project - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-1-2014 - FET-Open research projects - - - RIA - Research and Innovation action - - - Israel - - - MRG-GRammar - - - H2020-FETOPEN-2014-2015-RIA - - - 664918 - - - - - KUNGLIGA TEKNISKA HOEGSKOLAN - KUNGLIGA TEKNISKA HOEGSKOLAN - - - EUR 150 000 - - - Inkjet Printed Ultrafast Batteries and Large Integrated Capacitors - - - EUR 150 721,25 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Energy storage has become a global concern in modern society. With his ERC Advanced grant, Prof. Östling, an expert in solid state electronics from the KTH Royal Institute of Technology in Sweden, is trying to develop emerging - devices based on silicon technology but with other materials than silicon, such as graphene and its analogue MoS2. These unique materials offer opportunities to novel applications, especially those related to energy storage. Prof. Östling and his - team have recently developed an efficient inkjet printing technique to reliably deposit these materials at high resolution. They have been able to directly print graphene-based supercapacitors with good performance. In the new PoC project, they will - employ the inkjet printing techniques to demonstrate a novel type of energy storage devices which are expected to possess both high energy density and high power density, and establish initial commercialisation steps. Although the novel devices have - complicated structure, the full-printing solution will not evidently increase the production cost. Considering the improved performance, the effective cost is actually reduced. Furthermore, the printing solution facilitates scaling up during - commercialisation. These printed ultrafast batteries have great potential to meet the urgent and increasing demands from the rapid growth of portable electronic devices and electric vehicles. - - 2016-05-31, closed project - - - 2014-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2014 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Sweden - - - iPUBLIC - - - ERC-2014-PoC - - - 641416 - - - - - KUNGLIGA TEKNISKA HOEGSKOLAN - KUNGLIGA TEKNISKA HOEGSKOLAN - - - EUR 1 725 000 - - - Long-term molecular nanoscale imaging of neuronal function - - - EUR 1 725 000 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Synaptic function is difficult to analyze in living neurons using conventional optics, since the synaptic organelles and protein clusters are small and tightly spaced. The solution to this problem can come from the field of - super-resolution fluorescence microscopy, or nanoscopy. However, the current approaches to nanoscopy are still far from reaching this goal. Single molecule-based approaches (including STORM and PALM) provide high spatial resolution, but slow - recording, insufficient for live imaging. Ensemble approaches (including SSIM and STED) are able to record faster, but with poorer resolution or with high, potentially toxic, laser powers. It is currently impossible to image the same neuron for hours - and days, with both high spatial (~30 nm) and temporal (10-1000 Hz) resolution, and with minimal photodamage. My aim is to fill this gap, by developing, for the first time, a microscope that combines the advantages of both single molecule-based and - ensemble approaches. I will base the microscope on RESOLFT, a low-photodamage ensemble approach that I have pioneered recently. I will use line patterns to speed up the recording and 2photon-switching for 3D ability. I will combine this with - sensitive detection schemes that allow single-molecule detection and counting, relying on my previous expertise with PALM and GSDIM. The new set-up, termed molecular nanoscale long-term imaging with sequential acquisition (MoNaLISA), will track - neuronal organelles and proteins on different time scales, spanning from milliseconds to days, with a resolution close to the molecular scale. To obtain the first proof-of-principle results, I will address several issues still open in the synaptic - transmission field, relating to synaptic vesicle recycling, biogenesis and degradation. Overall, my project will introduce a novel paradigm to imaging in the life sciences, which will enable fast and quantitative nano-imaging of cells and tissues. - - 2020-03-31, ongoing project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Sweden - - - MoNaLISA - - - ERC-2014-STG - - - 638314 - - - - - UNIVERSIDAD POMPEU FABRA - UNIVERSIDAD POMPEU FABRA - - - EUR 811 750 - - - Justice and the Family: An Analysis of the Normative Significance of Procreation and Parenthood in a Just Society - - - EUR 811 750 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project examines the normative significance of procreation and parenthood for theories of justice. Important questions of justice about the family arise once we acknowledge and keep in view that procreation and parenthood - are both integral to the existence of any society (and therefore, a just society), and that they involve substantial benefits and burdens for parents, children, and society at large. Yet existing theories of justice generally neglect these questions - by assuming that the principles they formulate are to regulate the main institutions of societies constituted by fully formed adult individuals whose creation and care are taken as given. The project identifies and analyses three main sets of - questions about family justice: 1) Does justice require that parents and non-parents share, and share equally, the costs and benefits of having children, and how do different answers to this question bear on our theory of distributive justice? 2) - What are the claims of justice that we have as children, how do they relate to those we have as adults, and who bears the correlative duties? 3) Do all contemporaries, regardless of whether they are parents or non-parents, have the same obligations - of justice towards future generations, and how, if at all, are the justification and the content of those obligations affected by considerations about what parents owe their children and parents and non-parents owe to each other? Addressing these - questions contributes to developing normative-theoretical framework needed to address pressing public policy concerns, and also turns out to be more central to the formulation of a complete and defensible theory of justice than political philosophers - have realised to date. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Spain - - - Family Justice - - - ERC-2014-CoG - - - 648610 - - - - - KUNGLIGA TEKNISKA HOEGSKOLAN - KUNGLIGA TEKNISKA HOEGSKOLAN - - - EUR 146 897 - - - Industrial implementation of adaptive computational methods for turbulent flow and fluid-structure interaction - - - EUR 146 897 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The ERC StG project UNICON (Project ID 202984) was completed in July 2013. The goal of UNICON was to develop new adaptive finite element methods for computer simulation of fluid-structure interaction, in particular for - problems involving turbulent flow. Simulation of turbulent flow is an outstanding computational challenge, where the UNICON project made significant progress beyond the state of the art. The scientific results of the UNICON project include a new - theoretical and methodological framework, and a computer implementation of the methods as open source software, published as part of the FEniCS project, co-founded by the PI (Hoffman) in 2003. FEniCS is today a world leading open source software for - computer simulation based on differential equations, with an estimated 50 000 downloads per year, and the PI today leads the PRACE Tier-0 project FEniCS-HPC, in which algorithms and software are developed for the most powerful supercomputers in - Europe. Compared to competing simulation software, free as well as commercial, UNICON computational technology has proven to exhibit unique features with respect to accuracy and efficiency. - - - 2016-09-30, closed project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2014 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Sweden - - - ADAPTIVE - - - ERC-2014-PoC - - - 665630 - - - - - FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA - FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA - - - EUR 1 608 125 - - - High-frequency printed and direct-written Organic-hybrid Integrated Circuits - - - EUR 1 608 125 - - - Italy - Italy - - - Research Organisations - Chiara Andreoli - Tel.: +3901071781854 - Fax: +39 010 7170817 - Research Organisations - Chiara Andreoli - Tel.: +3901071781854 - Fax: +39 010 7170817 - - The HEROIC project aims at filling the gap between the currently low operation frequencies of printed, organic flexible electronics and the high-frequency regime, by demonstrating polymer-based field-effect transistors with - maximum operation frequencies of 1 GHz and complementary integrated logic circuits switching in the 10-100 MHz range, fabricated by means of printing and direct-writing scalable processes in order to retain low temperature manufacturability of - cost-effective large area electronics on plastic. The recent development of semiconducting polymers with mobilities in the range of 1 to 10 cm^2/Vs, and even higher in the case of aligned films, suggests that suitably downscaled printed polymer - transistors with operation frequencies in the GHz regime, at least three orders of magnitude higher than current printed polymer devices, are achievable, by addressing in a holistic approach the specific challenges set in the HEROIC - trans-disciplinary research programme: (i)development of scalable high resolution processes for the patterning of functional inks, where printing will be combined with direct-writing techniques such as fs-laser machining, both in an additive and - subtractive approach; (ii)development of printable nanoscale hybrid dielectrics with high specific capacitance, where low-k polymer buffer materials will be combined with solution processable high-k dielectrics, such as insulating metal oxides; - (iii)improvement of the control of charge injection and transport in printed polymer and hybrid semiconductors, where high-mobility 1-D and 2-D structures are included in polymer films; (iv)development of advanced printed and direct-written - transistors architectures with low parasitic capacitances for high-speed operation. HEROIC will radically advance and expand the applicability of polymer-based printed electronics, thus making it suitable for next generation portable and wearable - short-range wireless communicating devices with low power consumption. - - 2020-03-31, ongoing project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Italy - - - HEROIC - - - ERC-2014-STG - - - 638059 - - - - - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - - - EUR 185 076 - - - Multimodal Imaging of Disorders of Consciousness - - - EUR 185 076 - - - France - - - Research Organisations - - The diagnosis of individuals with disorders of consciousness has fundamental implications in terms of prognosis, treatment, palliative care and even proper end-of-life decisions. Diagnosis based on behavioural assessment is - difficult and it is believed that misdiagnosis occurs in a large percentage of cases (> 40%). Non-invasive functional brain imaging has recently emerged as a promising tool for the diagnosis of individuals with disorders of consciousness; however, - different imaging methods allow descriptions at limited spatial and temporal resolutions, and it is unknown how these findings relate to each other, to the underlying brain anatomy, and whether they are manifestations of a single fundamental - mechanism underlying the impairment of conscious awareness. - - - 2018-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - MIDOC - - - H2020-MSCA-IF-2015 - - - 702681 - - - - - UNIVERSIDAD POMPEU FABRA - - - EUR 170 121,60 - - - Technology and Political Change: Nuclear Power in the Post-Soviet Union - - - EUR 170 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - Focusing on the case of nuclear power in post-Soviet Russia and Ukraine (1990-present), this research and training project analyzes the relationship between political elites, scientific experts and the public in the context of - political change and incomplete democratization. The project will move beyond existing studies and analyze the co-evolution of risky technologies and political systems in transition. To date, research on political transition in Russia and Ukraine has - not sufficiently taken into account science and technology (S and T). Similarly, the analysis of S and T has been disconnected from changes in political institutions and practices. This project will consider how Ukrainian and Russian policy makers - and specialists have navigated new political circumstances and forms of public engagement to advance nuclear power programs. It will study how nuclear technologies are governed, how they are received in society, and evaluate public controversies over - costly and potentially risky large scale technological systems. This research has relevance for Horizon 2020 concerning reliable and clean energy, as well as the impact of technopolitical change on the European periphery on Europe's energy, security - and integration. - - - 2019-02-27, ongoing project - - - 2017-02-28 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - TechPolChange - - - H2020-MSCA-IF-2015 - - - 705577 - - - - - CORK INSTITUTE OF TECHNOLOGY - - - EUR 187 866 - - - Semiconductor laser with photonic crystal reflector for energy-efficient optical links - - - EUR 187 866 - - - Ireland - - - Higher or Secondary Education Establishments - - Our information society relies to an unprecedented extent on broadband communication technologies with applications such as high-speed internet access, cloud computing, data services, multimedia broadcast systems etc. The - amount of data processed by data centers continues to grow with a steep progression. We are unused to considering the energy cost of light communication, but it is huge, matching the airline industry. To meet the need for increased bandwidth, - compactness, reduced power consumption and cost effectiveness, we will develop new optical sources with narrow linewidth, high-speed frequency modulation and reduced power consumption that can be utilised in modern optical links. - - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Ireland - - - SELAPHOR - - - H2020-MSCA-IF-2015 - - - 703979 - - - - - UNIVERSITA CA' FOSCARI VENEZIA - - - EUR 180 277,20 - - - Civic community and public space in the ancient Near East. The case of Hittite Anatolia at the end of the Late Bronze Age (14th-13th centuries BCE). - - - EUR 180 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - "This project proposes to study public space of the ancient Near Eastern cities as a material correlate of civic communities. Civic communities acted as a significant political factor throughout the history of the ancient Near - East, both as institutions (e.g., assemblies) and as informal groups (the “town's crowd”). These forms of social aggregation were influential and often antagonistic alternatives to the monarchical and religious central powers. However, while the - Temple and the Palace as architectonic materializations of dominant powers engaged entire generations of archaeologists, the traces left by civic communities in the urban texture of the ancient cities have received far less attention. - - 2019-01-10, ongoing project - - - 2017-01-11 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - COMPUS - - - H2020-MSCA-IF-2015 - - - 703187 - - - - - UNIVERSITY OF KENT - - - EUR 183 454,80 - - - Restoration and Faith: practicing religion and conservation in Mexico's historic churches - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The proposed project addresses the restoration of a colonial era Catholic church located in a peripheral indigenous community in the state of Oaxaca, Mexico. It investigates the ways in which the professionals concerned with - the conservation of the church as a federally-protected historic site engage with the local religious community that has particular rights in, and relationships with, the building and objects that are to undergo repair. It raises larger political and - ethical questions of how divergent ideological, aesthetic and cultural values are negotiated in contexts of religious heritage conservation. This is a social anthropology project that is grounded in a broader multidisciplinary approach that connects - with art and architectural history, conservation sciences, and religious studies. The aims are to investigate: 1. the cultural, religious, and vocational ideologies and beliefs that come into conflict as actors work through restoration projects - together; 2. how the material and immaterial aspects of sacred and historically valuable objects are understood by different stakeholders; and 3. how relations of power are manifested and reinforced or resisted during restoration projects. These aims - will be achieved through 8 months of ethnographic research in Oaxaca with conservation experts associated with a private foundation that funds many restorations in the state, and with the local community and clergy in the municipality where the - church is located. This research will be supplemented by preparatory research at the University of Kent on heritage conservation practices and will be disseminated through an academic and public engagement plan that includes a public debate, a - photograph exhibition, an academic workshop, and two journal articles. - - 2018-11-30, ongoing project - - - 2016-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - MEXRES - - - H2020-MSCA-IF-2015 - - - 701601 - - - - - UNIVERSITY OF KENT - - - EUR 195 454,80 - - - Distributed Massive MIMO for Next Generation Wireless Communications - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - In view of the rapid increase in demand for mobile data services, next generation wireless communication systems will have to provide greatly increased capacity density and high data rates greater than 50Gbps. However, - satisfying these requirements for increasing numbers of users and connected devices, and increasingly bandwidth, processing power and energy-hungry applications will require a transformation in the way in which current mobile and wireless networks - perform. Recently, massive multiple input multiple output (MIMO) technology, where each base station (BS) is equipped with a large number of antenna elements (typically tens or even hundreds) has emerged as a key enabler to achieve a 1000 times data - rate and enormous spectral and energy efficiency. In order for massive MIMO to become a reality, the proposed work aims to explore transformative methods for the design of innovative techniques in 3 key challenging areas of massive MIMO communication - systems: (i) fundamental limits; (ii), (ii) transmission strategy; and (iii) caching mechanisms. The solution is achieved with small remote antenna units equipped with compact massive MIMO arrays deployed over certain coverage regions, and developing - practical signalling schemes, network coordination, and management protocols. - - 2018-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - FUTURE-MOBILE - - - H2020-MSCA-IF-2015 - - - 709291 - - - - - UNIVERSIDAD POMPEU FABRA - - - EUR 158 121,60 - - - Bayesian Monte Carlo for Global Illumination - - - EUR 158 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - One of the most challenging problems in computer graphics (CG) is to synthesize physically-based realistic images given an accurate model of a virtual scene. Rendering a photo-realistic image requires solving the illumination - integral which describes the light transport on a scene, and whose value is in general computed by resorting to numerical approximations such as those based on Monte Carlo (MC) methods. - - - 2018-07-31, ongoing project - - - 2016-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - BMC Rendering - - - H2020-MSCA-IF-2015 - - - 707027 - - - - - BEN-GURION UNIVERSITY OF THE NEGEV - - - EUR 182 509,20 - - - Type 1 reyanodine receptor Structure and regulation by post-translational modifications and small molecules. - - - EUR 182 509,20 - - - Israel - - - Higher or Secondary Education Establishments - - This proposal is aiming at understanding the structural basis of the type 1 ryanodine receptor (RyR1) regulation by post-translational modifications and by small molecules. RyR1 is present on the sarcoplasmic and endoplasmic - reticuli of many mammalian cell types, most notably, in skeletal muscles. RyR channels are required for calcium release from intracellular stores, a process essential for excitation-contraction (EC) coupling in skeletal (RyR1) and cardiac (RyR2) - muscles. They are amongst the largest ion channels, comprised of the four identical ~565 kDa channel-forming protomers. RyRs channel activity is regulated by post-translational modifications through multiple signaling pathways including adrenergic - stimulation. We have obtained a 4.3 Å resolution cryo-electron microscopy (Cryo-EM) structure of RyR1 in the closed state and a 3.6 Å structure in an activated state. An atomic model was built, defining the transmembrane pore, placing all cytosolic - domains as tertiary folds and unambiguously identifying small ligands including calcium, ATP, caffeine and the ryanodine in unprecedented details. In both data sets obtained, 3-D classification of particles revealed multiple distinct conformations - providing a broad detailed picture of the dynamic process of RyR1 gating. Here, I aim at improving and completing the atomic model of RyR1 and at determining the structural basis for RyR1 regulation by post-translational modifications and by small - molecules. I will use X-ray crystallography to determine the high-resolution structure of the full length RyR1 as well as small fragments including the transmembrane pore and drug binding sites. Cryo–EM and 3-D classification will be used to identify - structural changes induced by post-translational modifications and by native ligands and drugs binding. The mechanism of drugs targeting RyRs such as dantrolene and rycals can lead to structure-based design of more potent/safer drugs for malignant - hyperthermia and muscular dystrophy. - - 2018-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Israel - - - channelopathies - - - H2020-MSCA-IF-2015 - - - 708572 - - - - - UNIVERSITY COLLEGE LONDON - - - EUR 183 454,80 - - - Secure Quantum Communication and Computation - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Quantum Theory is one of the greatest scientific revolutions of the twentieth century. During the last decades, it has become apparent that the tools provided by quantum mechanics can be used in many fields, such as - cryptography, algorithms, game theory, and even biology. This is because quantum systems exhibit an intrinsic randomness that can be exploited in order to significantly boost computational performance, increase security of communications and in - general achieve tasks that are impossible with purely classical means. On the other hand, the use of quantum technologies in future telecommunication networks, raises important questions on the security of the currently deployed protocols since - quantum adversaries will be able to use quantum effects to break widely-deployed cryptosystems (e.g. RSA). - - 2019-02-05, ongoing project - - - 2017-02-06 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SeQuCom - - - H2020-MSCA-IF-2015 - - - 705194 - - - - - UNIVERSIDAD POMPEU FABRA - UNIVERSIDAD POMPEU FABRA - - - EUR 150 000 - - - Culture Aware Music Technologies - - - EUR 150 000 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The gap between the current capabilities of the music technologies used in commercial services and the needs of our culturally diverse world is still immense, e.g. in the several music traditions of culturally rich and diverse - India. The existing technologies fall short of utilizing even the basic musical characteristics and hence they limit our music listening experience. The consumption practices of services and products for Indian music vary to a large extent from those - of other popular music genres and they need to be addressed. An emerging market for digital music distribution in India will need music intelligence technologies that are adapted to local needs and music tastes. Hence, India is a natural venue to - assess the market potential and needs for culturally adapted information and communication technologies (ICTs) for music. Culture Aware Music Technologies (CAMUT) aims at bringing closer to market, the results of new research carried out to address - such a need. - - - 2017-04-30, closed project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2015 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Spain - - - CAMUT - - - ERC-2015-PoC - - - 680608 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - UNIVERSITE DE BORDEAUX - TECHNISCHE UNIVERSITAET KAISERSLAUTERN - RIJKSUNIVERSITEIT GRONINGEN - KUNGLIGA TEKNISKA HOEGSKOLAN - WEIZMANN INSTITUTE OF SCIENCE - WAGENINGEN UNIVERSITY - UNIVERSITE DE STRASBOURG - Novo Nordisk A/S - - - EUR 2 646 333,72 - - - Multi-Stimuli Responsive Molecular Systems and Materials - - - EUR 2 646 333,72 - - - United Kingdom - France - Germany - Netherlands - Sweden - Israel - Netherlands - France - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Nanotechnology has been identified as a key enabling technology of economic growth and the value of nanomaterials in the global market is forecast to grow to €2 trillion by 2015. In order to be a market leader in this area, it - is imperative that Europe invest in research where the gap between knowledge creation and successful commercialisation is bridged, and in training the next generation of highly skilled researchers in nanotechnology. This ETN will increase innovation - capacity and strengthen doctoral training in nanotechnology on a European level. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - ResMoSys - - - H2020-MSCA-ITN-2014 - - - 642192 - - - - - KUNGLIGA TEKNISKA HOEGSKOLAN - - - EUR 185 857,20 - - - From Landscapes to Earthscapes: Understanding Visual Cultures of Global Environmental Crisis and the Making of Global Environmental Images, 1945-present (EARTHSCAPES) - - - EUR 185 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - From Landscapes to Earthscapes: Understanding Visual Cultures of Global Environmental Crisis and the Making of Global Environmental Images, 1945-present (EARTHSCAPES) - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - EARTHSCAPES - - - H2020-MSCA-IF-2015 - - - 707593 - - - - - UNIVERSIDAD POMPEU FABRA - PHILIPS FRANCE - - - EUR 1 021 497,12 - - - Towards a novel paradigm for cardiac function assessment from imaging - - - EUR 1 021 497,12 - - - Spain - France - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Cardiovascular diseases have been defined as a top priority within H2020. Although diagnostic approaches and therapies have drastically improved over the last decennia, effective, validated and auditable tools for the - integrated assessment of cardiac function in clinical practice have yet to be developed. - - - 2019-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-EID - Marie Skłodowska-Curie Innovative Training Networks (ITN-EID) - - - MSCA-ITN-EID - European Industrial Doctorates - - - Spain - - - CardioFunXion - - - H2020-MSCA-ITN-2014 - - - 642676 - - - - - UNIVERSITY OF LEEDS - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - DEUTSCHES MUSEUM VON MEISTERWERKEN DER NATURWISSENSCHAFT UND TECHNIK - KUNGLIGA TEKNISKA HOEGSKOLAN - - - EUR 3 144 654,72 - - - Environmental Humanities for a Concerned Europe - - - EUR 3 144 654,72 - - - United Kingdom - Germany - Germany - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - - ENHANCE (Environmental Humanities for a Concerned Europe) will provide the first fully coordinated training programme for Environmental Humanities in Europe. It will train twelve early-stage researchers, joining three leading - universities for environmental research––the University of Leeds, Ludwig-Maximilians-University Munich, and the Royal Institute of Technology, Stockholm––with Europe's largest science and technology museum, the Deutsches Museum, and a further five - Associated Partners from the private and third sectors. - - - 2019-02-28, ongoing project | - - - 2015-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - ENHANCE - - - H2020-MSCA-ITN-2014 - - - 642935 - - - - - KUNGLIGA TEKNISKA HOEGSKOLAN - KUNGLIGA TEKNISKA HOEGSKOLAN - - - EUR 150 000 - - - Platform for Heterogeneous Integration of NEMS on ICs - - - EUR 150 000 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Within the ERC-M&M´s Starting Grant project (No.277879) we are exploring an innovative platform technology for wafer-level heterogeneous integration of integrated circuits (ICs) with micro/nano-electromechanical systems - (MEMS/NEMS). This type of heterogeneous 3D integration technology is part of the More-than-Moore paradigm depicted in the International Technology Roadmap for Semiconductors (ITRS) and allows the combination of standard CMOS-based integrated circuits - and high-performance MEMS devices to form complex and highly integrated systems that are not possible to manufacture with other micro-manufacturing approaches. First heterogeneous integration platforms for IC-integrated MEMS products have already - been commercialized with great success by InvenSense (USA) and by mCube (USA) in collaboration with TSMC (Taiwan), the world’s largest CMOS foundry. However, the established heterogeneous integration technologies have limitations with respect to the - type of MEMS devices that can be realized and the extent to which the MEMS-ICs system component can be miniaturized. The heterogeneous integration platform developed in this ERC-M&M’s+2 Proof of Concept proposal is suitable for a variety of - small-sized MEMS components with large-volume markets, including infrared (IR) detector arrays, micro-mirror arrays, ultra-low power circuits based on NEM switches (a specific target application are low-power FPGAs), gyroscopes, accelerometers, - microphones, etc. Thus, the heterogeneous integration platform is addressing a potential multi-billion € market. In contrast to the competing technologies, our heterogeneous integration platform is enabling the integration of ICs and MEMS/NEMS - devices with extremely small device dimensions in the nm-range, very small via dimensions in the sub-1μm-range and placement accuracies of the MEMS/NEMS components on the target ICs in the nm-range. - - 2016-12-31, closed project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2015 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Sweden - - - MaMs2 - - - ERC-2015-PoC - - - 680884 - - - - - UNIVERSITY OF KENT - UNIVERSITY OF KENT - - - EUR 149 917 - - - Add-on module for optical coherence tomography with en-face view option - - - EUR 149 917 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - By the end of the 4th year of the ERC Advanced grant, the PI has set up the basis of a unique procedure to perform optical coherence tomography (OCT) that is similar in outcome to time domain interferometry but has all - advantages of spectral domain interferometry in terms of speed and sensitivity. The new method of OCT, termed as Master/Slave (MS), is characterised by several advantages: direct production of an en-face OCT image, tolerance to dispersion that allows - MS-OCT to achieve the theoretical limit of axial resolution and sensitivity that can be tailored for no hardware and time cost, with the axial resolution. By excellence, the Master/Slave OCT method delivers en-face views direct, allowing lower cost - hardware and faster provision of en-face slicing and visualisation. An essential advantage is that of parallel processing, that makes MS-OCT, ideally suited to novel parallel optical configurations and graphic processing units (GPU). These advantages - can substantially increase the speed in providing volumes of the tissue, making the new OCT method superior to all other methods on the market. The POC support will help advance the MS-OCT closer to commercialisation. Four market strategies are - identified with immediate products for the first two. OCT add-on modules, equipped with MS software, for: A. OCT developers, to accelerate their research and B. OCT developers that can modify existing commercial OCT systems, by making them accomplish - the MS protocol. The module to be assembled and assessed for commercialisation will also pave the way to two more strategies: C. Companies already selling OCT systems on dedicated markets, where specialised agreements will widen the market and even - D. A full OCT system created by the new company, an ultimate outcome that requires investment, based on revenue acquired by selling the add-on modules. - - 2017-04-30, closed project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2015 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - AMEFOCT - - - ERC-2015-PoC - - - 680879 - - - - - TECHNISCHE UNIVERSITAET WIEN - TECHNISCHE UNIVERSITAET WIEN - KUNGLIGA TEKNISKA HOEGSKOLAN - - - EUR 149 625 - - - Non-Volatile Magnetic Flip Flop - - - EUR 149 625 - - - Austria - Austria - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The physical limits of CMOS scaling and the prohibitively high costs of future technology nodes, allows to foresee the end of further progress of CMOS technology in the near future and emphasizes the dire need to explore - alternative technologies and computational principles. - - 2017-08-31, closed project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2015 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Austria - - - NOVOFLOP - - - ERC-2015-PoC - - - 692653 - - - - - FORSCHUNGSVERBUND BERLIN EV - STOCKHOLMS UNIVERSITET - THE UNIVERSITY OF BIRMINGHAM - KUNGLIGA TEKNISKA HOEGSKOLAN - UNIVERSITAET BAYREUTH - IWW RHEINISCH-WESTFALISCHES INSTITUT FUER WASSER BERATUNGS-UND ENTWICKLUNGSGESELLSCHAFT MBH - Roehampton University - NATURALEA CONSERVACIO, SL - CRANFIELD UNIVERSITY - - - EUR 3 090 951,60 - - - Hyporheic Zone Processes – A training network for enhancing the understanding of complex physical, chemical and biological process interactions - - - EUR 3 090 951,60 - - - Germany - Sweden - United Kingdom - Sweden - Germany - Germany - United Kingdom - Spain - United Kingdom - - - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - Hyporheic zones (HZs) are key compartments for the functioning of aquatic ecosystems. As dynamic and complex transition regions between rivers and aquifers, they are characterized by the simultaneous occurrence of multiple - physical, biological and chemical processes. Turnover and degradation of nutrients and pollutants figure among the prominent ecological services the HZ provides. We are facing a significant knowledge gap in the understanding of how hyporheic - processes are linked and how they impact on each other. This can be attributed to a lack of truly supra-disciplinary research and harmonized and innovative investigation methods. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - HypoTRAIN - - - H2020-MSCA-ITN-2014 - - - 641939 - - - - - DET KONGELIGE DANSKE KUNSTAKADEMIS SKOLER FOR ARKITEKTUR, DESIGN OG KONSERVERING. - UNIVERSITY COLLEGE LONDON - UNIVERSITAET STUTTGART - UNIVERSITAT FUR ANGEWANDTE KUNST WIEN - KUNGLIGA TEKNISKA HOEGSKOLAN - INSTITUT D'ARQUITECTURA AVANCADA DE CATALUNYA - - - EUR 3 972 691,44 - - - Building Innovation in the Extended Digital Chain - - - EUR 3 972 691,44 - - - Denmark - United Kingdom - Germany - Austria - Sweden - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - The InnoChain ETN network is a shared research training environment examining how advances in digital design tools challenge building culture enabling more sustainable, more informed and more materially smart design solutions. - The network aims to train a new generation of interdisciplinary researchers with a strong industry focus that can effect real changes in the way we think, design and build our physical environment. - - - 2019-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Denmark - - - InnoChain - - - H2020-MSCA-ITN-2014 - - - 642877 - - - - - SELUXIT APS - AALBORG UNIVERSITET - - - EUR 100 000 - - - Collective Adaptive Systems Enabler Kit - - - EUR 100 000 - - - Denmark - Denmark - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - In 2008 Apple introduced the App Store. It was a watershed moment in the history of digitalization and it made a huge impact on human society. With the App Store, Apple created a sustainable model to leverage the potential of - mobile computing by tapping into the creativity of developers at large. - - - 2018-09-30, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-04-2016-2017 - FET Innovation Launchpad - - - CSA - Coordination and support action - - - Denmark - - - CASEK - - - H2020-FETOPEN-4-2016-2017 - - - 754506 - - - - - DEUTSCHES FORSCHUNGSZENTRUM FUR KUNSTLICHE INTELLIGENZ GMBH - UNIVERSITY OF SOUTHAMPTON - - - EUR 100 000 - - - Bringing persuasive computing training assistance for healthcare personnel from lab experiments to educational practice - - - EUR 100 000 - - - Germany - United Kingdom - - - Research Organisations - Higher or Secondary Education Establishments - - The aim of this proposal is to develop a strategy for transforming the results of a series of experiments in using persuasive computing technologies in emergency nurse training into a system that can be used in real life - educational settings. The experiments were conducted as part of the SmartSociety FET Open project, which aims to develop new ways of human-machine collaboration. They were jointly done by the partners of this proposal with DFKI being in charge of the - technology and Southampton providing the experimental setting within their nursing school that puts hundreds of professional nurses and nurse candidates through elaborate training simulations each year. The experiments have shown that sensor-based - activity recognition combined with novel interaction techniques can, in principle provide significant benefit to both the students and the trainers. They also generate significant interest within the health care community, which included both - enthusiasms for the potential and sepsis on potential problems. In this project, we want to understand which parts of the experiments are suitable for short to mid-term transition into real life education practice, how to overcome the corresponding - technical, regulatory and social hurdles and how the introduction of such systems could be financed. - - 2018-10-31, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-04-2016-2017 - FET Innovation Launchpad - - - CSA - Coordination and support action - - - Germany - - - SmartNurse - - - H2020-FETOPEN-4-2016-2017 - - - 754554 - - - - - UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN - KUNGLIGA TEKNISKA HOEGSKOLAN - KATHOLIEKE UNIVERSITEIT LEUVEN - CHARLES OWEN & COMPANY (BOW) LIMITED - LAZER SPORT NV - AGV SPA - - - EUR 3 387 265,56 - - - Head protection: a European training network for Advanced Designs in Safety - - - EUR 3 387 265,56 - - - Ireland - Sweden - Belgium - United Kingdom - Belgium - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Head injury is the most severe injury caused by motorcycling, bicycling, snowsports and equestrian activities, and it is the leading cause of death within these activities. Linear acceleration has been used extensively to - determine head injury risk, but it has been found that brain injury is actually influenced by angular kinematics. This is ignored by current injury criteria and product certification tests. To date, there is no consensus in terms of head injury due - to angular kinematics and this represents a significant gap in the state of the art. The scientific goal of HEADS is to improve the understanding of head impact injury and to design new helmet standard test methods that recognise the influence of - rotational kinematics. This will lead to improved helmets and a reduction in the severity of injuries and the numbers of fatalities. This objective will be achieved through a combination of computational simulations of real-life accidents, - experimental and computational investigation of injury thresholds, and design of new helmet certification tests. Another major objective of the network is to train a group of highly specialised doctoral graduates who are equally cognisant of head - impact biomechanics and helmet design technologies as well as being aware of commercialisable market opportunities. The ESRs will work in world-class facilities with highly qualified experts, and will benefit from the training scheme developed based - on the expertise of academic and industrial partners. This project will reach a new level of understanding of head injury and how head injury should be prevented, with directly applicable results to European industry. It will develop a well-networked - group of young engineers and scientists into world class researchers and innovators with numerous career paths open to them, who will advance technology for the benefit of society and maintain Europe as a global leader in industrial development. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Ireland - - - HEADS - - - H2020-MSCA-ITN-2014 - - - 642662 - - - - - TECHNISCHE UNIVERSITEIT DELFT - SINGLE QUANTUM BV - - - EUR 100 000 - - - Quantum Detectors - - - EUR 100 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - In HANAS (Hybrid Artificial and Natural Atomic Systems) storage in atomic quantum memories of single photons generated with novel quantum dot devices was demonstrated. Single photon detectors are crucial building blocks in - quantum memories and in follow-up technologies such as quantum repeaters and the quantum internet. For our experiments in HANAS, single photon detectors based on semiconducting avalanche photodiodes were first used until a new type of single photon - detectors based on superconducting nanostructures, originally developed for telecom wavelengths, was tested and greatly outperformed other detectors. This innovative detector makes complex quantum optics experiments far easier and faster to perform. - In Qdet, we will develop and fully benchmark a prototype based on these superconducting quantum detectors optimized for atomic frequencies and start the commercialization process with an industrial partner. We will establish superconducting single - photon detectors as the best systems for single photon detection in the near infrared, combining the highest detection efficiency, time resolution and lowest noise levels. A market research study and contacts with key players in the field will enable - us to identify launching customers and benchmark our systems for demanding applications in a new wavelength range. - - 2018-10-31, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-04-2016-2017 - FET Innovation Launchpad - - - CSA - Coordination and support action - - - Netherlands - - - Qdet - - - H2020-FETOPEN-4-2016-2017 - - - 754481 - - - - - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - - - EUR 100 000 - - - Industrial Exploitation and Market Uptake of a Temporal Cognition Toolbox for Commercial Robots - - - EUR 100 000 - - - Greece - - - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - - ENTIMENT aims to assess, deploy and commercialize a novel Temporal Cognition Toolbox (TCT) that greatly facilitates the development of time-aware robots, capable to engage in prolonged, symbiotic interaction with humans. In - doing so, it significantly capitalizes on the successful research and development activities on artificial time perception, pursued within the FET-funded project TimeStorm, which aims at equipping robots with a human-like sense of temporality and the - ability to perceive the temporal aspects of the world. The already available and tested robotic temporal cognition modules implemented in TimeStorm by partner FORTH, will be refined and integrated into the TCT, that will further be released as an - open source ROS node for robotic developers. - - - 2018-12-31, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-04-2016-2017 - FET Innovation Launchpad - - - CSA - Coordination and support action - - - Greece - - - ENTIMENT - - - H2020-FETOPEN-4-2016-2017 - - - 754423 - - - - - FUNDACION CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III - - - EUR 170 121,60 - - - Long range-acting drivers of premetastatic niches in melanoma - - - EUR 170 121,60 - - - Spain - - - Research Organisations - - Melanoma is the cancer with the fastest rising incidence world-wide, and although recent therapies can achieve unprecedented response rates, a significant fraction of patients still succumb to metastatic lesions. Key pending - questions in the field are the mechanisms underlying the inherent metastatic behaviour or melanoma, whereby seemingly thin primary lesions (≥2 mm in depth) bear high risk of dissemination to proximal lymph nodes and ultimately, to distal sites. A - dynamic crosstalk has been proposed to be established between melanoma cells and the lymphatic vasculature at tumour-draining lymph nodes, favouring an immune-permissive “lymphovascular niche”. However, whether (and how) these lymphovascular - interactions occur at distal sites is unclear. The Soengas group has generated unique “Lymphoreporter” melanoma mouse models for non-invasive and whole body imaging of tumour progression. These lymphoreporters demonstrated that primary melanomas - induce neo-lymphangiogenesis at distal pre-metastatic sites, already from very early stages of the disease, before dissemination occurs. Proteomic analyses were then performed to identify factors in the melanoma secretome that could drive these long - range-acting effects and subsequently filtered these proteins for novelty (i.e. no previous link to melanoma and lymphangiogenesis). Here I will focus on the top-ranking factors in this screening. In particular, I will define the impact of these - newly-identified melanoma secreted factors on tumour progression and metastasis, focusing on key components of the lymphovascular niche (i.e. on the crosstalk of tumour- vasculature-immune system). Secondly, I will assess the impact of these genes as - prognostic biomarkers and indicators of response to clinically-relevant treatments. These studies will be performed in collaboration with dermatologists, pathologists and oncologist to define the physiological relevance of our work. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - METMEL - - - H2020-MSCA-IF-2016 - - - 753442 - - - - - UNIVERSIDAD COMPLUTENSE DE MADRID - - - EUR 158 121,60 - - - Using Phase Change Materials for the Base Suspension in the Creation of NanoFluids - - - EUR 158 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - Nano-fluids (fluid bases with a nano-particle suspension) and Phase Change Materials (PCM) provide innovative ways to handle the increased need for heat transfer and thermal efficiency. But information regarding the thermal - properties (thermal conductivity, thermal diffusivity, enthalpy of transformation, enthalpy of fusion/melting, enthalpy of vaporization, specific heat, melting temperature, and crystallization temperature) of nano-fluids and PCMs is limited and - antiquated. Therefore, is the purpose of this action to determine the thermal properties of a number of PCMs to then use as the base fluid for a number of nano-fluids. This will be done by measuring n-alkanes in both the solid and liquid phases using - the transient hot wire and the differential scanning calorimetry (DSC) techniques. When possible, the obtained results will be compared with the scarcely available literature data. Lastly, the creation of a thermal properties prediction model for the - nano-fluids will be attempted. - - 2020-08-26, Grant Agreement signed - - - 2018-08-27 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - PCMNano - - - H2020-MSCA-IF-2016 - - - 753319 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 170 121,60 - - - Dressing Robotic Assistants for Persons with Reduced Mobility - - - EUR 170 121,60 - - - Spain - - - Research Organisations - - Physical disabilities due to illness, injury, or ageing can alter the way a person moves around the house, manipulates objects and senses their home. These issues make it harder for persons to execute daily home activities on - their own, and therefore specialized professionals are required to take care of them. However, the growing elderly population and the persons having basic activity difficulties or suffering from long-standing diseases are saturating the health - systems due to insufficient infrastructures and over-demand for health carers. Robotics-based solutions are a promising alternative to support the human labour at health care. This project focuses on how robotic assistants can be exploited to provide - independence and empower people with different kinds of mobility problems. Specifically, the main goal is to assist these persons in dressing themselves, which has been found to be an important task for independent living. In this sense, a robotic - dressing assistant needs to skilfully manipulate clothes, physically interact with the human, recognize his/her intentions and actions, and easily adapt to changes in the clothing, user posture, and degree of mobility of the assisted person. These - highly complex features are tackled in this proposal from a robot learning perspective, in which programming-by-demonstration, reinforcement and interactive learning will be combined to create both sophisticated manipulation skills and safe - assistance behaviours. The proposal envisions three different real experimental scenarios to test the proposed approaches and show their performance with real (able-bodied) participants (with restricted motion). This project will not only advance the - state of the art in assistive robotics, robot learning and human-safe control, but also will play a major role in helping persons with reduced mobility to live independently for longer and with a better quality of life. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - DRAPer - - - H2020-MSCA-IF-2016 - - - 753556 - - - - - UNIVERSITY OF DUNDEE - - - EUR 183 454,80 - - - Dissecting spinal cord ependymal cell heterogeneity by single-cell transcriptomics - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Cells with stem cell potential, this is with the ability to self-renew and generate specialised progeny, exist in the adult mammalian spinal cord. Previous studies localised this potential within the ependymal cell (EC) - population. However, ECs are rather heterogeneous based on their morphological features and the expression of a handful of neural stem cell markers. In this interdisciplinary research proposal, I aim to uncover the cellular and molecular - heterogeneity of ECs at the level of individual cells. I propose to take advantage of cutting-edge single-cell RNA-sequencing technology to obtain the transcriptomes of individual ECs from the spinal cord of adult mice. Using advanced computational - methods, I will establish EC types and states and use pseudotemporal ordering to elucidate potential lineage relationships among ECs. I will then validate these findings in the tissue context, using high-resolution confocal microscopy. This first - comprehensive characterisation of spinal cord ECs will provide novel and fundamental insights into how ECs possess and maintain their unique self-renewing properties. In the future, this will facilitate realisation of the potential of spinal cord - stem cells for therapeutic purposes. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ECtomics - - - H2020-MSCA-IF-2016 - - - 753812 - - - - - Eidgenössische Technische Hochschule Zürich - - - EUR 175 419,60 - - - Generation and Evolution Of Transform-Ridge Interaction and Behavior on Earth - - - EUR 175 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - Transform-ridge orthogonal patterns are fundamental features of the Earth’s plate tectonics. Although transform faults play a critical role in the organization of plate motions and are seismically active boundaries, it is - still enigmatic how they form and why they are maintained. So far, only regional-scale models of transform fault inception and evolution exist. As the result, relationships of these structures with global mantle flow and large-scale plate kinematics - remain unknown. The aim of this project is to advance our knowledge on global physical controls for the transform-ridge systems inception, dynamics and variability. I will take into account global forces to investigate nucleation and evolution of - transform-ridge interactions, thus bridging the gap between regional and global models. I will use my long-term expertise in geophysical modeling to implement new physics (such as rock damage and magmatism) in the state-of-the-art convection code - developed at ETH Zurich. I will run high-resolution 3D spherical models of global mantle convection to build the first database of simulated global transform-ridge patterns showing what factors influence the spacing and offset of transform faults. I - will develop methods to compare the synthetic data with collected observed field data (bathymetry, gravity data, seismicity) to assess which physical processes (e.g. crustal melting, rock healing) control the formation and distribution of - ridge-transform centers. Accounting for the global mantle and plate tectonic forces to explain transform fault dynamics is an unprecedented approach that is possible only now due to advances in physical properties of mantle rocks, numerical technics - and increasing available computational power. Through this multidisciplinary project I aim at the first assessment of how transform-ridge system guides the evolution of plates for long periods with the scope of keeping Europe at the vanguard of the - tectonics and geodynamical modeling research. - - 2020-03-31, Grant Agreement signed - - - 2018-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - GEOTRIBE - - - H2020-MSCA-IF-2016 - - - 753755 - - - - - UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA - - - EUR 158 121,60 - - - Excitonic quasiparticles in Titania - - - EUR 158 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - Although titanium dioxide (TiO2) is widely employed in fields like photovoltaics and photocatalysis, the nature of its fundamental charge transfer excitations is still unknown. A deep understanding of the excitonic properties - of TiO2 is of high relevance to achieve major advances in the aforementioned fields and may lead to the fabrication of new devices with enhanced performance in energy conversion applications. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - exciTitania - - - H2020-MSCA-IF-2016 - - - 753874 - - - - - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - - - EUR 175 419,60 - - - Two dimensional materials for lasing and frequency metrology - - - EUR 175 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - The recently discovered two dimensional 2D materials have opened up new possibilities for exploration of fundamental physics as well as device applications. Such materials offer new opportunities for ultra compact - optoelectronic devices. On the other hand, with the improvement in micro and nanofabrication techniques, it is now possible to fabricate ultra high Q microresonators (UHQ µresonators). A relevant example is the case of silica microtoroids, which due - to the whispering gallery modes, display one of the highest Q factors ever reported. - - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - 2DQOptics - - - H2020-MSCA-IF-2016 - - - 753718 - - - - - ECOLE NATIONALE SUPERIEURE D'ARTS ET METIERS - - - EUR 185 076 - - - Porous material Analysis Toolbox - Open source - - - EUR 185 076 - - - France - - - Higher or Secondary Education Establishments - - "The objective of the proposal is to advance fundamental science in reactive porous material modeling to foster innovation on the second pillar of the work program "Leadership in Enabling and Industrial Technologies". Starting - from the most advanced development done at NASA in the last decade, state-of-the-art reactive porous material models will be improved further with the contribution of expert theoreticians and implemented in a simulation tool released open source. The - fundamental developments will be validated and applied to design optimization and process innovation for two industrial applications. The first one is the design of efficient and optimized thermal protection systems for space exploration vehicles - (subprogram "space").The second one targets bio-hydrocarbon and bio-carbon production from lignocellulosic biomass. The biomass pyrolysis process will be studied from the wood-cell scale to the process level. The goal is to develop advanced - predictive engineering tools to enable process optimization and guide innovation in progress. This second effort will eventually benefit to two "Societal Challenges" of the work program: "Energy" and "Climate action, environment, resource efficiency, - and raw materials"." - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - France - - - PATO - - - H2020-MSCA-IF-2016 - - - 753412 - - - - - FUNDACIO CENTRE DE REGULACIO GENOMICA - - - EUR 170 121,60 - - - Comprehensive analysis of yeast expression-fitness functions (EFFs) - - - EUR 170 121,60 - - - Spain - - - Research Organisations - - Cellular and developmental processes rely on the precise activity of the proteins that constitute them, and alteration of protein activity often causes disease phenotypes and fitness defects. The relation between protein - activity (or expression) and organismal fitness is thus a fundamental genetic property with implications for evolutionary and disease processes. However, a systematic understanding of how protein expression relates to fitness is lacking. - - 2020-04-30, Grant Agreement signed - - - 2018-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - YEFF - - - H2020-MSCA-IF-2016 - - - 752809 - - - - - VRIJE UNIVERSITEIT BRUSSEL - - - EUR 172 800 - - - A LAB-ON-A-CHIP DEVICE FOR PURE CIRCULATING TUMOR CELL ISOLATION FROM WHOLE BLOOD FOR CANCER THERAPY - - - EUR 172 800 - - - Belgium - - - Higher or Secondary Education Establishments - - The overall objective of pureCTC is to realize a comprehensive lab-on-a-chip platform that redefines the state-of-the-art technology to address all the requirements for fast, efficient and reliable CTC isolation/purification from whole blood. - - 2019-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Belgium - - - pureCTC - - - H2020-MSCA-IF-2016 - - - 752516 - - - - - THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN - - - EUR 183 454,80 - - - Ecology and Evolution of Prospecting Strategies - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Prospecting behaviours allow individuals to gather personal and social information on the local quality of potential future breeding sites and help them make dispersal and settlement decisions. As it can have multiple - consequences on individual distribution, fitness and population dynamics, exploring the ecology and evolution of prospecting strategies is essential in a context of climate change. Yet, studies dealing with this topic are scarce because of - methodological and technological challenges. In this project, I will develop and apply novel theoretical and statistical approaches to deliver major new insights into the adaptive, ecological and evolutionary importance of prospecting strategies in - individual and population responses to environmental change. First, I will develop a spatially-explicit individual-based model to quantify the effects of local environmental conditions, life history traits and range margins on the evolution of - prospecting strategies. I will also test how inter-individual variation in these strategies may help or hinder populations in responding to rapid environmental change. Second, I will extend a state-space model to robustly quantify prospecting - movements from GPS tracking data. This will provide an innovative and powerful tool that will give new insights into the behavioural mechanisms involved in breeding habitat selection. Finally, I will integrate the underpinning knowledge gained from - the theoretical and empirical results to add new functionality to the existing platform RangeShifter. The multidisciplinary nature of the project is strong, involving a combination of evolutionary biology, behavioural ecology, movement ecology and - conservation biology. The project will open new perspectives in our fundamental understanding of breeding habitat selection and dispersal processes and will be essential to better predict and effectively manage species’ responses to climate change. - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - EcoEvoProspectS - - - H2020-MSCA-IF-2016 - - - 753420 - - - - - GEORG-AUGUST-UNIVERSITAT GOTTINGENSTIFTUNG OFFENTLICHEN RECHTS - - - EUR 171 460,80 - - - Ultrafast opto-electronic twists: Controlling the chirality of electrons and extreme-UV photons byultrafast laser pulses (UCHIRAL). - - - EUR 171 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - Chirality, describing the “handedness” of a system, is a fundamental property of physical entities such as magnets, spins, the DNA double-helix, or circularly and elliptically polarized light. This proposal aims at employing - intense ultrashort laser fields to control the chirality of two physical entities: photons of extreme-UV high harmonics, and free-flying electrons in a coherent pulsed beam. - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - UCHIRAL - - - H2020-MSCA-IF-2016 - - - 752533 - - - - - ACCADEMIA EUROPEA DI BOLZANO - - - EUR 180 277,20 - - - Intergovernmental relations in divided societies - - - EUR 180 277,20 - - - Italy - - - Research Organisations - - Many divided societies in Europe and beyond are grappling with identity-based political tensions and conflicts. Most recent examples are the post-election violence in Kenya, the ethnic unrest in Ethiopia, and, in Europe, the - continuing uncertainties about the territorial integrity of countries like Spain, the United Kingdom and Belgium in the face of secessionist claims. These and many other countries use territorial autonomies, within a federal or decentralised - framework, to manage their divided societies. A lot of research has been conducted about the relevance of territorial autonomies for divided societies in general. What needs attention, however, and has been neglected by studies so far, is the - integration of autonomous territories into the legal and political framework of the state, in particular, through their relations with the national government. Integrative intergovernmental institutions and processes are equally important because - they serve as a vehicle for promoting a cohesive society and reconciling the tension between unity and diversity. The IGR-IDS project focuses on investigating the relevance and effectiveness of intergovernmental institutions and processes in the - management of divided societies where territorial autonomies are used to deal with communal tensions. Using a comparative research method, it will identify and develop innovative integrative institutions and processes of intergovernmental relations. - The successful completion of the project will advance my career by allowing me to explore new areas of study in the management of divided society and facilitate my recognition as a highly rated researcher. I will emerge as an established expert on - intergovernmental relations in divided societies. That will put me in a position to progress on the academic ladder by placing a successful application for promotion to professorship. - - 2020-06-03, Grant Agreement signed - - - 2018-06-04 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - IGR-IDS - - - H2020-MSCA-IF-2016 - - - 752098 - - - - - UNIVERSITE DE LIEGE - - - EUR 160 800 - - - Characterization and monitoring of vigilance fluctuation in disorders of consciousness - - - EUR 160 800 - - - Belgium - - - Higher or Secondary Education Establishments - - This prospective exploratory study will aim at characterizing vigilance fluctuation in patients with disorders of consciousness (as defined by a change in diurnal behavioral response over time) using neurophysiological - parameters. We based this project on the assumption that changes at the Coma Recovery Scale-Revised scores (i.e., behavioral responsiveness) will be associated with a change in ocular measures and EEG complexity, suggesting that some of these - parameters could be used for monitoring vigilance in this population. We expect that this fluctuation will be particularly marked in patients with a minimally conscious state as compared with patients in an unresponsive wakefulness syndrome who will - display a more stable pattern of response over the two days. This project aims to better understand the course of vigilance fluctuation in DOC and to develop an objective tool based on biomarkers that could be used at bedside to determine the best - periods to assess and treat these patients. - - 2019-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Belgium - - - ADOC - - - H2020-MSCA-IF-2016 - - - 752686 - - - - - Eidgenössische Technische Hochschule Zürich - University of California San Francisco School of Medicine - - - EUR 247 840,20 - - - Patient specific magnetic resonance image guided biomechanical modelling of the heart – Anovel tool towards personalized medicine in heart failure - - - EUR 247 840,20 - - - Switzerland - United States - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Heart failure (HF) is a progressing disease currently affecting 2% of the population in the developed world with a mortality rate of 50% within the first five years. While HF with reduced ejection fraction, primarily - associated with myocardial infarction, can be detected with sufficient accuracy, HF with preserved ejection fraction is far more difficult to diagnose. Accordingly, there is an urgent need to better diagnose these patients to ultimately guide and - improve treatment. Among the clinical imaging modalities, Cardiovascular Magnetic Resonance (CMR) is the gold standard for assessing cardiac mass and ejection fraction, and is capable to assess local cardiac mechanics and tissue properties. Beyond - these established methods, cardiac diffusion tensor imaging has emerged as a new tool to enable insights into the microscopic morphology of the beating heart. Unfortunately, due to scan time limitations during clinical routine, compromises in spatial - resolution and coverage have to be made. To overcome practical limitations of clinical in vivo CMR imaging and to enable prediction of disease progression for individual patients, additional tools are required. To this end, biomechanical models have - attracted considerable attention. Once adapted sufficiently to in-vivo imaging, these models promise patient-specific insights into causes and progression of disease and, help guiding treatment. It is the objective of the present fellowship proposal - to significantly advance patient-specific, image-guided modelling of HF by incorporating the most recent developments in both CMR imaging and biophysical modelling. The proposed framework will address limitations of current approaches, which impose - generic assumptions about cardiac tissue properties and structure. With recent innovations in CMR imaging, as developed by the applicant, data on local changes of myocardial microstructure will be obtained to achieve the next level of diagnostic and - predictive cardiac modelling of HF. - - 2020-08-31, Grant Agreement terminated - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Switzerland - - - CMRPredict - - - H2020-MSCA-IF-2016 - - - 752466 - - - - - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - - - EUR 183 454,80 - - - Unique TNFα lysine myristoylation; elucidating its function, regulation and integration into inflammation - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Tumour Necrosis Factor-alpha (TNFa) is an important cytokine implicated in many autoimmune and inflammatory disorders, in which TNFa-blocking antibody drugs have become first line treatment. Nevertheless, clinical responses - are variable. To improve and expand therapeutic strategies, a better understanding of TNFa and the many other cytokines secreted from cells is crucial. It was recently shown that TNFa is myristoylated on a lysine residue (KMyr), a unique modification - that suggests an important but yet unexplored role for KMyr in cytokine biology. I will investigate the impact of KMyr on TNFa signalling, and its wider role in secretion and signalling of other cytokines, using a unique multi-disciplinary approach - combining state-of-the-art chemical biology tools with molecular cell biology and proteomics. The role of KMyr in TNFa trafficking, secretion and signalling will be identified using human macrophage cell lines that produce mutant TNFa proteins with - the relevant lysine residue substituted or deleted. KMyr proteins will be identified through a powerful approach that introduces a small chemical tag into the myristate in cells; this tag can be selectively functionalized to allow sensitive - fluorescence imaging of KMyr within living cells, and purification for identification by mass spectrometry. The global scope of KMyr in the proteome will be analyzed in parallel, with emphasis on other secreted cytokines such as IL1alpha, which may - be controlled too via KMyr. Regulation of TNF KMyr will be explored by identifying KMyr transferases and demyristoylases using chemical photo-affinity tools that can bind proteins interacting with KMyr, yielding putative targets for future first line - therapies. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - TNFaLysMyr - - - H2020-MSCA-IF-2016 - - - 752165 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 170 121,60 - - - Tuning both the photoluminescence and conductive properties of new COP materials - - - EUR 170 121,60 - - - Spain - - - Research Organisations - - The main goal of this proposed project is the synthesis of new hybrid π-conjugated polymers for industrial use, which conductive and optical properties could be fine tuneable by the proper anionic metallacarboranes as doping - agents. To achieve our goals two directions were chosen. In the first part we would like to investigate the effect of different boron clusters ([Co(C2B9HnX11-n)2]- X=Cl, Br, I) as doping agents on the conductive and photoluminescence properties of - the poly(3,4-ethylenedioxythiophene) (PEDOT). Preliminary results suggest that the earlier used [Co(C2B9H11)2]- doping anion is redoxactive, thus it has a big influence on the formation and the properties of the polymer. Our expectation is that the - halogen analogues ([Co(C2B9HnX11-n)2]-=Cl, Br, I) cover a wide range of redoxpotential, thus we can easily modify the properties of the new materials. During the second part we would like to tune both the conductive and photoluminescence properties - of the poly(p-phenylene vinylene) (PPV). For this purpose different co-polymer planed to synthetized, which containing different amount of non-doped and self-doped monomer units. (In case of the self-doped polymer the doping anion is covalently - linked to the monomer unit). We expect that the ratio of the non-doped and the self-doped has a strong influence both the conductive and photoluminescent properties, moreover the two different properties will be altered by the inclusion of functional - side groups. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - Tuning COPs - - - H2020-MSCA-IF-2016 - - - 751587 - - - - - FONDATION NATIONALE DES SCIENCES POLITIQUES - - - EUR 173 076 - - - The Young Christian Workers Movement and the radicalization of Social Conflict in Mediterranean Europe: France, Italy and Spain (1963-1978) - - - EUR 173 076 - - - France - - - Higher or Secondary Education Establishments - - "The Work-Christ project intends to reconstruct the influence of religious radicalisation on the social conflict in Mediterranean European countries, with particular attention paid to the cases in France, Spain and Italy - during the sixties and seventies. The main purpose of this research is to study the relationship between religion and politics in the period following the Second Vatican Council, via the study of the "Young Christian Workers Movement", better known - by the French name Jeunesse Ouvrière Chrétienne. This is a field of research which is totally unexplored, both regarding the interactions among the different national offshoots of the movement and the transnational reality represented by the - coordinating authority of the Jeunesse Ouvrière catholique internationale. The research will also take into account the network constituted by the Mouvement Mondial des Travailleurs Chrétiens (MMTC) to which the specialized branches of the working - class Catholic Action organisations referred to. From the late sixties, the Christian workers’ associations became the terminal point of the tensions, ferment and expectations that arose from the Second Vatican Council. In addition, these - associations played an essential role in the processes of transition and consolidation of democracy in the three nations taken into consideration. For these reasons, the “Young Christian Workers Movement” appears to be a case study of the utmost - importance for the role played on a European scale as a workshop for the building of a radicalized young identity challenging societal norms. Work-Christ has 3 key objectives: 1. through research based on archive sources, address the innovative - subject of international Christian workers’ youth associations; 2. adopt a multi-disciplinary and interdisciplinary perspective for studying religious radicalisation; 3. study the mobilisation of the Christian workers associations at transnational - level, reconstructing the phases, the goals and the contents." - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - WORK-CHRIST - - - H2020-MSCA-IF-2016 - - - 751592 - - - - - UNIVERSITAT POLITECNICA DE CATALUNYA - - - EUR 170 121,60 - - - A database of experimental biomaterials and their biological effect - - - EUR 170 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - The advent of material science and manufacturing techniques in the last century has led to the development of thousands of novel biomaterials, with potential to revolutionise health care. However, the vast majority of - biomaterial studies do not progress beyond the stages of design and testing, and therefore a substantial amount of scientific data is only available in the form of research publications. To date, there is no database curating the experimental data - generated by testing novel biomaterials in vitro and in vivo, representing a loss of a valuable big (experimental) data. In here, we propose an open-access database of experimental tissue scaffolds, indexing design features, cellular and tissue - responses, thus creating an exhaustive inventory of experimental scaffolds. Such a dataset would enable scientists to efficiently search and interpret relevant information from past studies across all tissues and models, as well as create - computational tools to predict and optimise cell-material interaction. A comprehensive map of research activity and findings should also make it easier to identify areas where data is missing or lacking. A systematic, up-to-date overview of the field - will also be a useful tool for science policy making. The novelty of the project lies not only in the concept of curating data from laboratory evaluation of experimental biomaterials (rather than just approved medical implants), but also in - attempting to face the methodological challenge of extracting and structuring information from the heterogeneous and vast field of experimental biomaterials. One of the keys of this interdisciplinary project is crowd-sourcing biomaterial scientists, - thus engaging their expertise and understanding their needs, in order to create a comprehensive, relevant and useful tool to enhance research in the field. - - 2020-04-30, Grant Agreement signed - - - 2018-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - DEBBIE - - - H2020-MSCA-IF-2016 - - - 751277 - - - - - LINKOPINGS UNIVERSITET - - - EUR 185 857,20 - - - Towards Stable and Highly Efficient Tin-based Perovskite Solar Cells - - - EUR 185 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - Developing new energy sources is an urgent issue, as fossil fuels will be exhausted in near future. Solar cells system is a promising renewable energy technology that converts sunlight to electricity. Today, crystalline - silicon exhibits high power conversion efficiencies (PCE) and dominates the solar panel industry. The problem of silicon solar cells is that it suffers from high production cost due to tedious processing condition. Recently, organic-lead-halide - perovskites have offered the promise of a breakthrough for next-generation solar cell devices, and the PCE is up to 22.6% over the past few years. In spite of high efficiency, the presence of toxic lead (Pb) will become problematic in the future for - widespread deployment of this technology. It is prospective to replace Pb with less toxic tin (Sn). However, the poor stability (the easily oxidization of Sn2+ to Sn4+ by O2) and low efficiency are two major issues of Sn-based perovskites. This - proposal targets air-stable, high efficient Sn-based perovskite solar cells by developing new Sn-based perovskites and electron transporting layer to match the band energy of perovskites. The expected fruits of the project will contribute to European - excellence and competiveness in renewable energy field. The successful transfer of the results will promote economic growth and job supplies. In addition to the scientific objectives, the proposal will help the fellow to new acquire knowledge and - reinforce his quality as an independent researcher, such as creativity, independent thinking, leadership and transfer qualities, which are critical for the fellow to secure a long-term position in a European university/institution, and eventually - become a world renowned expert in the energy research field. - - 2020-07-31, Grant Agreement signed - - - 2018-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - TinPSC - - - H2020-MSCA-IF-2016 - - - 751375 - - - - - HASKOLI ISLANDS - - - EUR 179 325,60 - - - Eruption Source Parameters for Explosive Eruptions in Iceland Over the Last 3 ka - - - EUR 179 325,60 - - - Iceland - - - Higher or Secondary Education Establishments - - Eruption source parameters (ESPs)—such as erupted volume/mass, plume height, magma discharge, tephra dispersal, and total grain size distribution (TDGS)—are key information for characterizing explosive eruptions and essential - input parameters in tephra dispersal models used for real-time forecasting by the Volcanic Ash Advisory Centers (VAACs) and for long-term hazard assessments. Iceland is one of the volcanically most active regions of the world, with over 20 events per - century. About ~700 events are preserved in the post-glacial soil and lake sediments in Iceland. ESPs, however, have yet to be determined for most of the eruptions. ESPs are traditionally derived using empirical approaches, requiring detailed field - measurements of the deposits. The objective of this action is to estimate, to the first order, the ESPs for explosive eruptions in Iceland using inversion modelling. The advantage of this approach is that it bypasses the compilation of detailed - isopach maps through the use of optimization algorithms. It requires only a limited number of thickness measurements and grain size analyses. Consequently, ESPs can be established for a larger number of eruptions in a shorter time, than when using - traditional empirical methods. This will result in a statistically robust data set on ESPs used for determining the magnitude and intensities of explosive eruptions in Iceland as well as for assessing risk and mitigating hazards associated with such - events. - - 2019-06-14, ongoing project - - - 2017-06-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Iceland - - - ESPSI - - - H2020-MSCA-IF-2016 - - - 750733 - - - - - UNIVERSITY OF CYPRUS - - - EUR 151 648,80 - - - The use of glazing traditions to examine the dynamics of interaction between cultures in contact: A case study of Cypriot glazed wares from the 11th to 17th centuries AD - - - EUR 151 648,80 - - - Cyprus - - - Higher or Secondary Education Establishments - - GLAZE seeks to investigate the suitability of using glazing traditions to reflect the dynamics of interaction between cultures in contact. Cypriot glazed ceramics dating to the 11th and 17th centuries AD, a period when - fundamental socio-political changes occurred in the region, will constitute our principal case study. GLAZE has two key research questions: - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Cyprus - - - GLAZE - - - H2020-MSCA-IF-2016 - - - 750904 - - - - - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - - - EUR 183 454,80 - - - Complex Dynamics and Strange Attractors through Non-Autonomous Bifurcations - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - This project aims at substantial contributions to the bifurcation theory of non-autonomous dynamical systems. The main research efforts will focus on an analytical investigation of the principles behind the creation of complex - dynamical behaviour and strange attractors in the most common kinds of non-autonomous bifurcations: saddle-node and Hopf bifurcations. The project further aims at an interdisciplinary application of the analytical findings to the problem of the - predictability of ice ages. - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - CDSANAB - - - H2020-MSCA-IF-2016 - - - 750865 - - - - - THE UNIVERSITY OF SHEFFIELD - - - EUR 195 454,80 - - - Reuse of Waste Materials for Fire-Spalling-Proof and Crack-Resistant Sustainable Concrete - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Fire-induced explosive spalling (violent peeling-off of concrete cover) and plastic shrinkage cracking are major issues for concrete infrastructure. Tunnels and buildings can experience catastrophic failure due to fire - spalling, as well as premature deterioration due to cracking, leading to huge economic costs and loss of life. In any new project, EU directives and codes of practice require adequate solutions for the spalling/cracking problems whilst all major - existing road tunnels need to be upgraded. However, the mechanisms of fire spalling and shrinkage cracking are not well understood, and there are no guaranteed spalling/cracking prevention measures. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - FireCracker - - - H2020-MSCA-IF-2016 - - - 750764 - - - - - UNIVERSIDAD DE CORDOBA - - - EUR 170 121,60 - - - Fusarium oxysporum mediated underpinning of cell type-specific modulation in multiple host interaction - - - EUR 170 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - Fungi have a devastating impact on human nutrition and health. Each year, fungal pathogens provoke enormous agricultural losses in crop plants and contaminating food with harmful mycotoxins. The soil-borne fungal pathogen - Fusarium oxysporum infects plant root and vascular tissue, causing wilt disease in over a hundred different crops, including both dicots and monocots. A particular aggressive strain of this pathogen, tropical race 4, is threatening banana plantations - worldwide. Currently, there is little information on the crucial biotrophic infection stage of vascular pathogens, from penetration of root to colonization of xylem vessels. Fusarium provides an excellent model to investigate the cell-specific - sensing and adaptation and suppression of plant immunity related to early infection stages. The host group has recently reported the chemotrophic sensing mechanism used by this pathogen, and identified host plant signals perceived by Fusarium in the - soil. Moreover, their work revealed a combined action of enzymes involved in fungal cell wall remodelling and plant cell wall degradation which contributes in virulence of this pathogen. In this project, we aim to identify the cell-specific virulence - genes that F. oxysporum uses to colonize a dicot host (Arabidopsis) versus monocot (Banana) that has a fundamentally distinct vascular tissue architecture. We will use dual RNA-Seq coupled with Laser capture microdissection (LCM) to identify core - compatibility components in both the pathogen and the plant, that are essential for establishing wilt disease. This will lead to identification and characterization of potential targets in this interaction that could be used to develop novel - resistance strategies in ongoing banana breeding efforts. This project will thus advance fundamental knowledge of how a fungus senses and colonizes such a broad host range, while creating new opportunities for crop protection by dissecting the - interaction at a cell-type specific resolution. - - 2020-06-30, Grant Agreement signed - - - 2018-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - FOUNDATION - - - H2020-MSCA-IF-2016 - - - 750669 - - - - - VIB - - - EUR 172 800 - - - INTEGRATION OF PLANT ORGANELLE COMMUNICATION UNDER ENVIRONMENTAL STRESS - - - EUR 172 800 - - - Belgium - - - Research Organisations - - Environmental challenges such as drought, temperature and light extremes can impose oxidative stress in multiple organelles, thus negatively affecting the function of plant cells. Both chloroplasts and mitochondria can invoke - signaling pathways to the nucleus that trigger stress responses and adjustment of cellular homeostasis, resulting in physiological outcomes such as enhanced stress tolerance, or conversely programmed cell death. These pathways include the - 3'-phosphoadenosine 5'-phosphate (PAP)-SAL1 pathway for chloroplasts and the ANAC013 mobile transcription factor for mitochondria. However, the mechanisms by which plant cells coordinate different signals from chloroplasts and mitochondria for - whole-cell acclimation to oxidative stress are still enigmatic. Whether there is any cross-talk between chloroplast and mitochondrial signaling is also intriguing. My project will investigate these fundamental questions using an exemplar model system - consisting of three components that combine my research with the Hosts’. The first goal is to take my PNAS findings that SAL1 is a redox-regulated initiator of chloroplast signaling and determine if a similar mechanism occurs in the mitochondria, - where SAL1 is also localized. This would reveal how two distinct organelles can integrate oxidative stress sensing and response by using the same pathway. Second, the interaction between SAL1-redox sensing and the mitochondrial signaling transducer - ANAC013 will be investigated to understand integration between these two apparently distinct pathways. Third, ANAC013 targets a biosynthetic enzyme for PAP hinting at crosstalk between mitochondrial and chloroplast signaling at the level of signal - metabolism. Thus, my research on SAL1-PAP and VIB’s on ANAC013 collectively present a unique opportunity to reveal how the two pathways are linked at different levels enabling cellular signaling to be coordinated across scales to facilitate a - harmonic, not discordant acclimation response. - - 2020-03-11, Grant Agreement signed - - - 2018-03-12 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Belgium - - - IN-PLANTO_CUES - - - H2020-MSCA-IF-2016 - - - 750907 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 170 121,60 - - - Understanding how Inositol Polyphosphates regulate autophagy and lipid body formation in photosynthetic organisms: crosstalk with TOR signaling. - - - EUR 170 121,60 - - - Spain - - - Research Organisations - - The elucidation of regulatory networks that govern cell growth and carbon storage in photosynthetic cells may potentially benefit the world's dependence on the declining reserves of fossil fuels. The growth/carbon sink - relationship impacts metabolism, carbon partitioning and productivity but its regulation is poorly understood. Recently, we found a connection between two major cell growth regulators in the model green alga Chlamydomonas reinhardtii. Our findings - revealed a synergistic effect between TOR kinase and Inositol polyphosphate (InsP) regulating lipid metabolism and the recycling process of autophagy. Based on the relevance of these results, we aim to find the mechanisms and the conditions in which - this intersection takes place within the green lineage. In this sense, we have designed a straight-forward project including different goals. First, we will set novel analytical tools to evaluate the InsP level fluctuations in the presence of new TOR - inhibitors and monitor the impact on autophagy flux and lipid metabolism in the model photosynthetic organisms Chlamydomonas reinhardtii and Arabidopsis thaliana. Second, we want to identify the phosphorylation targets of InsPs using - Kinome/P-phosphoproteome in a Chlamydomonas InsP-deficient mutant. This analysis will unravel the phosphorylation network of InsP signaling and will provide new insights about the role of InsP in the control of cell growth. Third, we will evaluate - InsP levels, autophagy flux and lipid storage under nutritional stress to determine the InsP modulation response in plants and algae. Understanding this signaling pathway will impact metabolic engineering of food and biofuel crops to improve yields - of high-value products including oils and lipids. We believe this project will impact a general audience and will help to teach people how basic research can turn into a greater understanding of a process that is conserved in humans and has a direct - economic impact. - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Spain - - - INSPirAUTOR - - - H2020-MSCA-IF-2016 - - - 750996 - - - - - ISTANBUL TEKNIK UNIVERSITESI - - - EUR 157 845,60 - - - Microwave Diagnosis of Breast Cancer with Open Ended Contact Probes - - - EUR 157 845,60 - - - Turkey - - - Higher or Secondary Education Establishments - - This action proposes to carry out research in open ended contact probe (OECP) technique to lay out foundation work for development of two new applications: an automated surgical margin detection device for breast cancer - treatment and an automated microwave biopsy probe for breast cancer diagnosis. While the envisioned applications require a single and highly accurate measurement, OECP technique suffers from high error and low repeatability dielectric property - measurements. The error mostly stems from the current mathematical approach utilized for the dielectric property retrieval which may converge to local minimum and can magnify the measurement set-up based errors. This research will first target the - existing error by proposing robust mathematical retrieval approaches. Next, application based modifications will be investigated with new probe structures. Finally, further error minimization will be achieved by introducing classification algorithms. - Developed techniques will be validated with animal experiments. The outcomes of this research will greatly contribute to the innovation of new medical devices that can be utilized for breast cancer, representing one of the most commonly diagnosed - cancer type among women. The researcher is well-equipped and has the required capabilities to execute the objectives of this research. The host organization and supervisors have an extensive track record in medical device development, necessary - infrastructure, network, and expertise. This research will allow the researcher to become independent by extending her network, publication/grant track record, skill sets, and more importantly, through joining an innovation oriented host - organization, the researcher will gain expertise in phases that enables the research to be transformed into innovation. Finally, the goal of the proposed research, building the foundation for innovation, is also in line with ‘Future and Emerging - Technologies’ call of the H2020 work program. - - 2019-05-07, ongoing project - - - 2017-05-08 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Turkey - - - MIDxPRO - - - H2020-MSCA-IF-2016 - - - 750346 - - - - - THE BABRAHAM INSTITUTE - - - EUR 195 454,80 - - - Maternal Obesity and Epigenetic Reprogramming: from Gametogenesis to Early Embryonic Development - - - EUR 195 454,80 - - - United Kingdom - - - Research Organisations - - Obesity is a worldwide epidemic with major health consequences. One devastating consequence of obesity is ovarian failure and infertility in women. Obesity causes endocrine dysfunction that compromises particularly the female - gamete, the oocyte. Importantly, maternal obesity also affects the offspring, predisposing children to obesity and type 2 diabetes. - - - 2019-11-30, ongoing project - - - 2017-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - MOBER - - - H2020-MSCA-IF-2016 - - - 750478 - - - - - LONDON SOUTH BANK UNIVERSITY LBG - - - EUR 195 454,80 - - - Biocementation for railway earthworks - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - In a number of European countries, old railway transport infrastructure earthworks are suffering from serviceability problems or failures and need continuing and costly maintenance/remediation works. This is becoming a major - constraint for railway owners and operators, especially in the light of the increased risk of hazards posed by climate change. The hypothesis of this research is that biocementation (a technique that uses natural biological processes to bind soil - grains) is a viable and sustainable technique for improving the structural stability of railway earthworks, and hence, the resilience of the EU’s transport infrastructure. The hypothesis will be tested through the application of the technique on - earthwork materials of the UK rail network. After establishing improved microbial systems and processes, the project will involve advanced soil testing. The testing will give high quality data on the hydromechanical properties and behaviour of - biocemented soils. Careful consideration will be given to the behaviour of the soil under unsaturated soil conditions (soil voids partially filled with water) which has not been researched. The data will be interpreted by constitutive modelling of - the soil behaviour. The model will be implemented to commercial software, giving researchers and engineers a useful predictive tool for the analysis and design of biocemented soils. Having assessed the technique and the durability of the - biocementation in the laboratory, a significant advance of this research will be the pilot application of the technique on actual railway assets, made accessible by a major owner and operator of railway infrastructure. This novel technique is - proposed to be environmentally superior to conventional grouts (which are toxic) and other common soil stabilisers, e.g. cement or lime (linked to high CO2 emissions). Overall it is more sustainable because the micro-organisms used are renewable, - environmentally friendly and safe (non-pathogenic). - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - BioRail - - - H2020-MSCA-IF-2016 - - - 750587 - - - - - UNIVERSITY OF LIMERICK - THE UNIVERSITY OF SYDNEY - - - EUR 254 313 - - - COsts and Mechanisms of Personalised Exercise and Education for chronic Low back pain - - - EUR 254 313 - - - Ireland - Australia - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Back pain is the leading cause of disability in Europe. Chronic low back pain (CLBP) is the most costly and burdensome form. As the EU population ages, there is an urgent need for more clinically and cost-effective therapies - to ensure sustainable healthcare. Dr O’Keeffe will explore a personalised medicine approach to exercise and education for CLBP. This is cutting edge, and has shown promising results beyond other therapies. Dr O’Keeffe is the perfect match for this - project, as she has led a trial on this novel therapy for her PhD. This will be the first project to examine the mechanisms, response, and the cost-effectiveness of personalised exercise and education for CLBP. This will build on Dr O’Keeffe’s - experience to expand and develop her skills in this area. Dr O’Keeffe will be trained in mediation, moderation and economic evaluation. She will gain additional research skills in new study designs, research software, physical activity measurement, - gender analysis and public patient involvement. She will gain transferable skills in communication and public engagement, interdisciplinary networking, grantsmanship, project management, leadership and supervision. She will gain exposure to the - non-academic sector through a secondment to a non-governmental organisation. Dr O’Keeffe will disseminate her results through open-access journals and conferences. She will communicate her results and Marie Sklodowska-Curie experience through social - media, TV, radio and European Research events. If awarded this fellowship, Dr O’Keeffe will be equipped with the right skillset to improve her employability and reach a position of professional maturity. She will expand the European Research Area by - strengthening networks. She will put Europe at the forefront of excellence and innovation for CLBP by promoting a safe exercise and education therapy for EU citizens. This will allow billions of euro that the EU currently spends on CLBP to be - redirected to other health care services. - - 2021-01-07, ongoing project - - - 2018-01-08 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Ireland - - - COMPEL - - - H2020-MSCA-IF-2016 - - - 750492 - - - - - UNIVERSITETET I BERGEN - - - EUR 208 400,40 - - - Decadal changes in the Atlantic Equatorial Mode. Origin and dynamics. - - - EUR 208 400,40 - - - Norway - - - Higher or Secondary Education Establishments - - Understanding the multidecadal variations of the Atlantic Equatorial Mode (EM) is important for climate prediction and climate services, because it is the first mode of variability in the tropical Atlantic in summer and has a - worldwide impact on climate, including the West African Monsoon, rainfall in Nordeste (Brasil), European heat waves and ENSO phenomenon. - - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Norway - - - DEMODA - - - H2020-MSCA-IF-2016 - - - 750156 - - - - - Eidgenössische Technische Hochschule Zürich - - - EUR 175 419,60 - - - Development of synaptic networks in songbirds - - - EUR 175 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - Vocal learning in songbirds is a complex sensorimotor behaviour with many established parallels to human speech and language learning. Here we aim to resolve the neural ultra-structure of a key premotor area in the songbird - brain, HVC (proper name). HVC plays a major role in song learning and takes part in both song perception and production. To understand the neural mechanisms of tutor song memorization and emergence of stereotyped adult song, we plan to map the - networks of HVC’s afferent and efferent synaptic connections and to explore the experience dependence of these connections during tutor-based song learning. - - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - DESYNE - - - H2020-MSCA-IF-2016 - - - 750055 - - - - - UNIVERSIDAD DE SANTIAGO DE COMPOSTELA - - - EUR 158 121,60 - - - Photoresponsive Smart Nanocarriers for Tetherless Regeneration of Bone Tissue - - - EUR 158 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - The research aim of PhotoNanoBone is to develop of a novel nanotechnological strategy based on stimuli-responsive nanocarriers together with a microfluidic platform for spatiotemporal control of cell reprogramming and - differentiation of 3D cell cultures towards bone tissue engineering. - - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - PhotoNanoBone - - - H2020-MSCA-IF-2016 - - - 749667 - - - - - RIJKSUNIVERSITEIT GRONINGEN - - - EUR 177 598,80 - - - Structure-function relationship of chimeric KdpFABC complex - - - EUR 177 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - The structure-function relationships that explain the transport mechanism of membrane proteins on a molecular level are poorly understood and define one of the most complex and interdisciplinary research fields at the - interface of Biology, Chemistry and Physics. Here I propose the investigation of the KdpFABC complex for the potassium uptake into the cell. It combines features of three membrane transport systems (P-type ATPases, channels and ABC transporters), - which traditionally are considered to be mechanistically and structurally distinct. I propose to decipher the mechanism of action of the KdpFABC system, which is likely to overthrow the conceptual boundaries conventionally used to describe membrane - transport mechanisms. The work might lead to the design of novel antibiotics, as these systems are exclusively found in prokaryotes. The structural studies will be conducted exploiting the recent breakthroughs in high-resolution single particle cryo - electron microscopy (cryo-EM) that will be established by me as experienced researcher and thereby contribute to the cutting-edge research at UG. The complementary expertise of myself in structural biology and of Prof. Slotboom, as a world-leading - scientist in the functional characterization of membrane proteins, are ideally suitable for the successful completion of the research objectives. Ultimately, this project will provide me a unique opportunity to establish myself as an independent - researcher and use the knowledge and skills acquired to obtain an academic position within the EU. - - 2019-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - KdpFABC - - - H2020-MSCA-IF-2016 - - - 749732 - - - - - UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6 - - - EUR 246 668,40 - - - Exploring the mechanisms underlying the evolution of plastids through the study of an unusual nitrogen-fixing symbiosis - - - EUR 246 668,40 - - - France - - - Higher or Secondary Education Establishments - - Symbioses are evident sources of innovation in nature, critical for the evolution of plastids and the success of eukaryotes on Earth. The mechanisms promoting such relationships, however, are difficult to identify, especially - between single-celled organisms, and remain largely unknown. A widespread symbiosis was recently discovered in the ocean between an unicellular cyanobacterium (UCYN-A) and single-celled eukaryotic algae (prymnesiophyte). UCYN-A lacks typical - cyanobacterial features such as the capacity to perform oxygenic photosynthesis, CO2 fixation or the tricarboxylic acid cycle, and must thus rely on the supply of organic matter from the algal host. In turn, UCYN-A shows a dramatic genome reduction - with a high specialization in nitrogen fixation, providing fixed nitrogen to the alga. Given the importance of nitrogen for the algal productivity, it has been hypothesized that UCYN-A could eventually give rise to a nitrogen-fixing plastid in a - process analogous to the origin of chloroplasts. This project aims to study the UCYN-A symbiosis both from an evolutionary and a functional point of view: First, the identification and characterization of new associations from marine samples at a - global scale through molecular techniques will allow a deep comparison of closely-related symbiotic lineages that will help to understand the evolutionary underpinnings of this symbiosis. Second, nutrient incubation experiments of seawater samples - over diel cycles will be performed to identify potential factors regulating the carbon and nitrogen exchange between partners to gain knowledge on the host-symbiont coupling mechanisms. For this purpose, metatranscriptomic analysis and electron - microscopy combined with molecular probes and quantitative isotopic techniques (FISH-nanoSIMS) will be applied. Elucidating the mechanisms underlying this unusual nitrogen fixing symbiosis will provide valuable insight into previously unknown - processes explaining the evolution of plastids - - 2020-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - France - - - UCYN2PLAST - - - H2020-MSCA-IF-2016 - - - 749380 - - - - - THE UNIVERSITY OF BIRMINGHAM - - - EUR 195 454,80 - - - Labelling of engineered nanomaterials for nanosafety tracing - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Major uncertainty still exists on the safety of engineered nanomaterials (ENMs). This is primarily due to difficulties in studying such small-scale objects and especially tracing their fate and behaviour in laboratory - experiments and, even more so, the environment. Labelling of ENMs can serve a very important role of tracer in the environment, and ultimately be used as a tool to create unique ENM identities and support the concept of “safer-by-design”. The - proposed project will compare different labelling techniques, both conventional (fluorescent labels) and emerging (stable isotopic and chemical labelling) where the host and ER have complementary expertise, and investigate multiple labels. It will - consider aspects of industrial synthesis and scaling up and carry out a field experiment involving labelled ENMs. The ER will be hosted by the team who pioneered stable isotope labelling of ENMs and benefit from placements with the JRC and Glantreo, - whilst bringing to the project his own unique expertise on ENM synthesis and tracing. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - NanoLabels - - - H2020-MSCA-IF-2016 - - - 750455 - - - - - SCUOLA NORMALE SUPERIORE - - - EUR 168 277,20 - - - CACHEM: Probing Clustering of X-ray AGN using Chandra and Semi-Empirical Models - - - EUR 168 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - The presence of a supermassive black hole (BH) in almost all galaxies in the Universe is an accepted paradigm in astronomy. How these BHs form and how they co-evolve with the host galaxy is one of the most intriguing - unanswered problems in modern Cosmology and of extreme relevance to understand the issue of galaxy formation. - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - CACHEM - - - H2020-MSCA-IF-2016 - - - 749348 - - - - - UNIVERSITAT WIEN - - - EUR 166 156,80 - - - The King’s City: A Comparative Study of Royal Patronage in Assur, Nineveh, and Babylon in the First Millennium BCE - - - EUR 166 156,80 - - - Austria - - - Higher or Secondary Education Establishments - - Cities first developed in the fourth millennium BCE in Mesopotamia and quickly became the centers of civilization. Despite extensive work on urban landscapes from an archaeological perspective, these ancient cities remain - poorly understood. Even less studied are royal capitals, the seats of kingship when empires emerged in the first millennium BCE. This project explores capitals from the two main, competing empires—Neo-Assyrian and Neo-Babylonian—to address key - questions: what constitutes a royal capital and what distinguishes it from other important cities? How are capitals conceptualized by the kings who inhabit, establish, and renovate them? What are the effects of the kings’ presence in and patronage of - the capital cities on the urban fabric and the social and economic structure of the urban population? By juxtaposing the Assyrian capitals in Assur and Nineveh with the Babylonian capital of Babylon as case studies, this research uses a novel - comparative approach based on a methodology that combines philology, religious studies, and social and political history to answer these questions. Uniting materials from the highest levels of state such as royal inscriptions, decrees, and letters - with administrative, economic, and private archives, and joining these textual records with archaeological evidence through the lens of royal patronage, this project employs an innovative holistic and interdisciplinary framework to reveal how the - kings’ ideological and official relationships to their capitals affects the social and bureaucratic structures of these cities. The project capitalizes on the knowledge transfer between the researcher’s Neo-Assyrian specialty and the host - institution’s Neo-Babylonian expertise. The project’s results have great potential to revolutionize our understanding of cities and royal power in the ancient world, and to make accessible a wealth of new data for fields as diverse as history, - anthropology, sociology, urban studies, and political science. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Austria - - - RoyalCities - - - H2020-MSCA-IF-2016 - - - 749965 - - - - - HASKOLI ISLANDS - - - EUR 191 325,60 - - - Household Ecology. Consumption and Wellbeing in Early Modern Iceland - - - EUR 191 325,60 - - - Iceland - - - Higher or Secondary Education Establishments - - "HECoW's aims are to quantify and qualify an observed increase in domestic consumption in early modern Iceland (1750-1900) in order to assess the effects new household material culture had on gender relations and the wellbeing - of families. This will be achieved through an truly interdisciplinary, historical and archaeological, methodology applied to two different data sources: historical probate inventories and artefact assemblages from archaeological excavations. These - sources will provide information on what new materials were consumed by families during this period, how their introduction and spread varied across the social spectrum, from poorer labourers to land owning farmers, and how they were distributed - through time. - - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Iceland - - - HECoW - - - H2020-MSCA-IF-2016 - - - 748698 - - - - - STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN - - - EUR 165 598,80 - - - Gravitational Waves and Electromagnetic Counterparts from Generic Binary Neutron Star Systems - - - EUR 165 598,80 - - - Netherlands - - - Research Organisations - - The research project will pave the way for a better understanding of the binary neutron star (BNS) merger process with a view on the detection of gravitational waves (GWs) and electromagnetic (EM) signals. - - - 2020-01-14, ongoing project - - - 2018-01-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - BNSmergers - - - H2020-MSCA-IF-2016 - - - 749145 - - - - - VRIJE UNIVERSITEIT BRUSSEL - - - EUR 172 800 - - - Epistemic Optimism in Enlightenment Natural Philosophy : Metaphysics and Experimental Philosophy - - - EUR 172 800 - - - Belgium - - - Higher or Secondary Education Establishments - - From a methodological point of view, the history of the classical sciences is often presented as a triumphant march of experimentation anchored in the science of Newton and the Newtonians. The historiography of 18th-c. - scientific methodology tends moreover to portray each form of persistence of metaphysics as the sign of resistance to modernity or as some obsolete archaism. The aim of my research project is to bring a twofold shift to this traditional - interpretation. First, by shedding light on the presence of other experimental traditions, some older than, some contemporary with the Newtonian one, that explain how Newton's natural philosophy was received and, second, by showing that within a - certain number of 18th-c. scientific methodologies there was a fertile interaction between experimentation and metaphysics. The idea of the project is to propose a novel historiographical hypothesis about the epistemic values of Enlightenment - science. My research hypothesis is based on an innovative methodological idea: namely that one should study epistemic practises in order to identify communities of shared epistemic values. This proposal will go beyond the classical divisions which - have long dominated accounts of Enlightenment science (e.g. rationalists versus empiricists, Cartesians versus Newtonians, etc.). It will focus on the Dutch Republic from 1690 to 1750, because the aim is to scrutinize how Newton’s Principia and - Opticks were received within an already existing experimental context. The focus here will be on two questions that occupied 18th-c. scientists: What knowledge do experiments provide us with? And, how can it be rendered certain? To understand how the - development of experimental philosophy in the Dutch Republic managed to reconfigure epistemic concerns without totally erasing metaphysical preoccupations. My intention is to test a research hypothesis: the epistemic optimism of 18th-c. natural - philosophy. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Belgium - - - EPISTOP - - - H2020-MSCA-IF-2016 - - - 748623 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 158 121,60 - - - Enabling Multifunctional Plasmonics on Hybrid Artificial Scale-Integrated Systems - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - Optical isolator, or optical diode, is a device, which allows the transmission of light in only one direction. They are used in fibre optic communication to prevent back reflections and improve signal-to-noise ratio. The - development of on-chip optical communications requires downscaling of optical components, e.g replacing optical fibres with nanoscale waveguides. The miniaturization of optical isolators is therefore a key step towards integrated photonic circuits. - We approach this challenge by taking advantage of surface plasmon resonances that can squeeze light down to nanoscale dimensions. We combine plasmonic waveguides with ferroelectric and -magnetic materials that, in turn, break the space-inversion and - time reversal symmetries to create non-reciprocal conditions for light propagation. The ferroelectric and magnetic materials provide us with an additional interesting advantage: their optical properties can be adjusted by applying external electric - and magnetic fields, enabling active control over light in nanoscale. The proposed research project brings together the candidate’s expertise in plasmonics and the hosting group’s established knowledge in oxide thin films. This creates excellent - conditions for training through research and knowledge transfer. We envision two significant outcomes: (i) demonstration of a proof-of-concept plasmonic isolator based on symmetry considerations and (ii) assessing the viability of using active oxide - materials as tools to control plasmon propagation with external fields. The H2020 Innovation Union initiative strives to drive economic growth in the EU by innovation. In line with this strategy, we recognize that EMPHASIS offers ample potential for - technological applications and include strategies to ensure that the potential can be realized. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - EMPHASIS - - - H2020-MSCA-IF-2016 - - - 748429 - - - - - BRITISH MUSEUM - - - EUR 195 454,80 - - - The Western European Acheulian Project - - - EUR 195 454,80 - - - United Kingdom - - - Research Organisations - - The Western European Acheulean Project (WEAP) aims to characterize the occupational pattern of western Europe during the Middle Pleistocene (MP) –700 to 300Ka–, through the study of Acheulean technology. Recent research has - shown that the Atlantic seaboard is the most likely route for colonisation due to the more oceanic climate compared to eastern Europe and to the richer range of resources in coastal areas. Due to cyclical changes in climate with glaciations and - interglacials, northern Europe was frequently depopulated and then recolonized through this period probably from source areas in southern France and Iberia. This route-way should therefore bear witness to the cultural links between north and south. - From 1 million to 600,000 years ago there is evidence of brief pioneering events in north-west Europe with a small number of sites and small numbers of stone tool artefacts. After 600,000 year ago more sustained occupation is shown by the increase in - sites and the much large stone tool assemblages. They also show technological innovation in the form handaxes and possibly in the use of fire, clothing and shelter, which led to the first sustained occupation of northern latitudes. Although there has - been much research and new sites excavated over the last twenty years, there has been little integration between the work in Spain, Britain and France. Based on the applicant’s previous experience, WEAP proposes to create a common method of analysis - for the study of six Middle Pleistocene sites from UK and France –in agreement with three Middle Pleistocene technologists–, the use of the experimental technology to complete the archaeological record, and the use of new methodological approaches, - such as the 3D scanning technology as the most appropriated statistical analysis, to improve understanding of behavioural patterns in order to build models of human dispersals from south-west to north-west Europe. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - WEAP - - - H2020-MSCA-IF-2016 - - - 748316 - - - - - UNIVERSIDAD COMPLUTENSE DE MADRID - - - EUR 158 121,60 - - - Theoretical and Numerical Analysis of Antifreeze and Ice Nucleator Proteins:Coarse-Grain Approach for Multiscale Study and Bio-Engineering - - - EUR 158 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - In nature there are many organisms able to control the ice nucleation rate of water. This ability allows such organisms to adapt to environmental changes, like large temperatures excursions, and to facilitate the search for food. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - ProFrost - - - H2020-MSCA-IF-2016 - - - 748170 - - - - - FUNDACION CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III - - - EUR 158 121,60 - - - Role of infiltrating neutrophils in tissue homeostasis - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - Neutrophils follow daily cycles of release from and migration back into the bone marrow, where they are eliminated. After searching for the presence of neutrophils across multiple tissues of healthy mice under steady state, my - host laboratory found neutrophils in most of the tissue analyzed. These findings require the study of the role of neutrophils in their tissue of destination. Several studies have shown that neutrophil clearance might be a significant source of - homeostatic signals able to functionally modulate the tissues and organs where they are eliminated. In addition, specific functions for neutrophils in the spleen have already been described. I hypothesize that neutrophils may have important roles for - the homeostasis and functioning of the tissues that they infiltrate, and that they acquire tissue-specific phenotypes that favor their local functions. - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - TISSUENEU - - - H2020-MSCA-IF-2016 - - - 748381 - - - - - UNIVERSITE DE NAMUR ASBL - - - EUR 172 800 - - - The virulence potential of human pathogens: how Acinetobacter baumannii survives Acanthamoeba castellanii predation - - - EUR 172 800 - - - Belgium - - - Higher or Secondary Education Establishments - - The human pathogen Acinetobacter baumannii represents a deadly threat to human health. Despite its established clinical relevance, the pathogenicity of this nosocomial superbug is poorly understood. The biphasic amoeba - Acanthamoeba castellanii is a cellular infection model broadly used to decipher the virulence mechanisms of human pathogens, as bacterial resistance upon amoebal predation (grazing) are often correlated with their pathogenicity potential in human. - However, high-throughput screening approaches to investigate the virulence mechanisms of A. baumannii using this amoeba in an infection context are still lacking. - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Belgium - - - ACtIVAtE - - - H2020-MSCA-IF-2016 - - - 748032 - - - - - UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA - - - EUR 158 121,60 - - - Bogomolov Multiplier - - - EUR 158 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - This project is dedicated to studying a geometric invariant called the Bogomolov multiplier. The main objectives of the proposed project are threefold. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - BogomolovMultiplier - - - H2020-MSCA-IF-2016 - - - 748129 - - - - - THE UNIVERSITY OF BIRMINGHAM - - - EUR 183 454,80 - - - Active-site modulation of metal-ligand Coordinated complex electrocatalysts for PEFCs - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - In polymer electrolyte fuel cells (PEFCs), the commonly used catalysts are still carbon supported Pt-based nanoparticles (Pt/C), which undesirably increases the overall cost of the system. To address this challenge, advanced - non-precious group metal (NPGM) catalysts have been endeavoured due to their potential low cost and high CO tolerance. Although rapid progress has been achieved in recent years, the poor activity and stability of NPGM catalysts can still not compete - with the conventional Pt/C catalysts. - - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - CoordPEFC - - - H2020-MSCA-IF-2016 - - - 747889 - - - - - UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA - - - EUR 180 277,20 - - - Definition, analysis and interpretation of a new typology of the Roman House: The TetrastyleCourtyard House, a domus with a hybrid cultural conception sheltered by a global civilization ofAntiquity - - - EUR 180 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - "In the recent decades, some studies have found a particular typology of Roman house in different parts of the Empire. This typological feature is the result of a hybrid house scheme be-tween the Greek and Roman conceptions of - the house. The new typology has been observed in different Roman cities with a Greek past, but in different geographical contexts and chronologies. This type of home, with its variants, has not been enough analysed by the Roman domestic architecture - studies. There are still many Roman cities with a Greek past which private architecture has not been thoroughly studied. - - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - Italy - - - TETRASTYLON - - - H2020-MSCA-IF-2016 - - - 747466 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 158 121,60 - - - Origins and evolution of programmed cell death machinery during the emergence of animal multicellularity - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - Programmed cell death (PCD) is an essential function in multicellular organisms; it regulates normal development, responses to cell damage, and cell turnover. Accordingly, the PCD machinery present in the unicellular ancestors - of animals was likely critical to the emergence of the complex multicellularity found in extant animals. However, we lack a full understanding of the PCD repertoire in the unicellular relatives of animals, and whether that ancestral repertoire - underwent significant changes at the onset of Metazoa - - 2020-02-29, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - HoloCellDeath - - - H2020-MSCA-IF-2016 - - - 747789 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 173 076 - - - Dissecting the chromatin dynamics at telomeres during mouse pre-implantation development. - - - EUR 173 076 - - - France - - - Research Organisations - - In the last decades, the progress in medicine have contributed to extend human lifespan considerably. Unfortunately, this aging of populations gives rise to the increased appearance of degenerative diseases and cancers, and - therefore represents a critical problem for public health. During embryonic development, cellular proliferation is an essential process that is required to generate all the tissues and organs that contribute to the adult organism. However, - alterations in the molecular mechanisms regulating this fundamental process can drive developmental defects and tumors. Cellular fail-safe systems evolved to prevent these events to happen. One of them is the natural shortening of chromosome ends, - termed the telomeres. This “molecular clock” prevents cells from proliferating if their telomeres become critically short, which could lead to chromosomal alterations. This mechanism is responsible for cellular aging in Human. Unfortunately, cancer - cells can bypass this process through the activation of telomere maintenance mechanism allowing for virtually unlimited proliferation. Interestingly, such maintenance mechanisms naturally occur during early embryonic development. The proposed - research is aimed at understanding how telomeres are regulated in this system and under a physiological context. My expertise in mouse embryonic work associated with the competences in telomere biology of the host laboratory of Dr. Jerome Déjardin - will likely be a suitable combination to answer these questions. On the long term, these researches could lead to the discovery of key factors regulating telomere maintenance. Finally, as the suppression of telomere length maintenance inhibits cell - growth, the present proposal could contribute to the development of new treatments against cancer or precocious aging. - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - TeloChromatin - - - H2020-MSCA-IF-2016 - - - 748017 - - - - - STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN - - - EUR 165 598,80 - - - Transformations with Neutrals and Turbo analyses - - - EUR 165 598,80 - - - Netherlands - - - Research Organisations - - The LHCb experiment at CERN was created in order to investigate decays of beauty and charm mesons produced in the proton collisions of the Large Hadron Collider (LHC). Through measurements of the observables in such decays, - for example amplitudes and phases in the angular distributions of decay products, the effects of New Physics can be discovered. Disproving the Standard Model (SM) predictions through so-called flavour observables is an exciting approach to discover - the answers to the questions the SM cannot solve, such as the source of the matter-antimatter differences necessary for our existence. The large backgrounds present in proton-proton collisions mean that large quantities of data must be processed, for - example if all events were kept from the nominal LHCb luminosity, this would equate to ~50PB of raw data. The TNT project will enhance the physics abilities of the LHCb experiment, and will also dictate the future direction of Big Data analytics in - High Energy Physics. The first two goals of this TNT project involve two new analyses of b→s transitions decaying to neutral particles, namely Bd→K*(→KSπ0)μμ and Bs→γγ, that provide complementary experimental inputs to New Physics searches. The study - of these transitions will expand the physics case for the LHCb experiment and will involve the creation of new collaboration tools for the optimisation of all analyses with a single neutral particle. The third and final goal of the TNT project aims - to optimise the LHCb data processing model through the extensive use of real-time analysis. Building on the success in 2015 and 2016 of the Turbo stream, allowing physics analyses to be performed with the LHCb trigger event reconstruction, the - extension of this principle to flexibly save any required part of the event will transform the data processing model, permit all LHCb analyses to be performed in real time. - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - TNT - - - H2020-MSCA-IF-2016 - - - 747822 - - - - - UNIVERSITEIT VAN AMSTERDAM - - - EUR 165 598,80 - - - Counterfactual Knowledge from the Imagination - - - EUR 165 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Thoughts about counterfactual situations are a central feature of human cognition, key to planning in any domain of activity: What would happen if I missed a mortgage payment? What if Britain were to leave the EU? It seems - that knowledge about counterfactual situations is possible under some circumstances. The project’s general aim is to improve our understanding of those circumstances, and what role the imagination plays in specifying them. The specific objectives are - to investigate: (1) the connection between the epistemology of counterfactual conditionals and the epistemology of claims involving modal terms like “possible”, “necessary”, and “can”, (2) the role of the imagination in the epistemology of thought - experiments in science, and (3) the cognitive architecture underlying counterfactual thinking. Over the course of investigating (1)-(3), I develop and defend the view that certain constrained imaginative exercises can provide knowledge about - counterfactual situations. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - CKI - - - H2020-MSCA-IF-2016 - - - 747658 - - - - - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - - - EUR 183 454,80 - - - AttoDNA: how electronic motions affect the photostability of the genomic material - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - AttoDNA considers the early (attosecond to few-femtosecond) events following photo-excitation/ionisation in DNA/RNA canonical and non-canonical nucleobases for the first time. This involves the electronic movement before the - onset of nuclear dynamics, ascertaining the length in which this initial purely electronic motion extends in time and how it affects the ensuing nuclear dynamics and its outcome with regards to the photostability shown by the genomic material from a - bottom-up approach. By monitoring the electronic and nuclear motions in canonical and non-canonical nucleobases, the way in which they couple can be elucidated and the specific motions contributing to photostability extracted from a novel standpoint. - - 2020-02-29, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - AttoDNA - - - H2020-MSCA-IF-2016 - - - 747662 - - - - - UNIVERSITA DEGLI STUDI DI PADOVA - - - EUR 168 277,20 - - - Scattering Amplitudes for Higgs Production at High-Order as touchstone for Automated Multiloop Feynman Calculus - - - EUR 168 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - Scattering Amplitudes sit at the core of quantum field theory. On the one side, they capture the high energy regimes of fundamental interactions among elementary particles, hence, their accurate determination is a crucial test - for the predictive power of the theoretical frameworks Particle Physics is based on. On the other side, scattering amplitudes are the tiniest mathematical lab of the Universe, where more formal investigations about the symmetries ruling particle - interactions can be performed. New relations and dualities involving scattering amplitudes may become manifest only through their actual calculations at higher orders in perturbation theory, yet invisible to the canonical approach to quantum field - theory. Therefore, progress in the ability of computing scattering amplitudes at very high accuracy is crucial for understanding the fundamental interactions and for providing accurate predictions within phenomenological analyses. HiProLoop aims at - providing the most accurate determination of the virtual contributions to amplitudes relevant for Higgs phenomenology, by considering 1) the associated production of a Higgs boson and a jet at 2-loop, 2) the Higgs boson production in gluon fusion at - 3-loop, as well as 3) the photon-pair production in association with a jet at 2-loop. The latter process is an important background to the process-1, and it can also be considered as a touchstone for the automation of generic 2-loop scattering - amplitudes at high multiplicity. This effort should culminate in the development of a solid framework for the evaluation of generic 2-loop scattering amplitudes, which represent a currently open, urgent problem. Therefore the results of HiProLoop - will become milestones for the theoretical physics community. HiProLoop will exploit mutual exchange of competences and tools between Theoretical Physics, Algebraic Geometry, Number Theory and Computer Science. The dissemination of the results will - follow an ambitious communication plan. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - HiProLoop - - - H2020-MSCA-IF-2016 - - - 747178 - - - - - UNIVERSITY OF LEICESTER - - - EUR 183 454,80 - - - Analysing the migration choices of HIV-positive gay men in England and France - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Despite improvements in available therapies and investments in prevention campaigns, HIV-rates continue to rise across European cities. Gay men are over-represented amongst people with HIV, thus experiencing the combined - effects of homophobia and HIV-related stigma. Several studies have found a correlation between becoming HIV-positive and gay men’s decision to migrate, although most of them rely on quantitative methodologies and concern the US and Canada. In a - European context we have very limited knowledge about the reasons why HIV-positive gay men choose to migrate to, and remain in, specific urban areas across the continent. This research project aims at addressing this gap in knowledge by investigating - different migration patterns of HIV-positive gay men towards Birmingham and Brighton (England) and Marseille and Paris (France) at different historical times (the mid ‘80s/early ‘90s with the diffusion of the epidemic and a stigmatizing public - discourse; the mid ‘90s/early 2000s with a new focus on prevention from health institutions and the introduction of effective therapies; the last decade with the introduction of a single drug-therapy and the recent introduction of Pre-Exposure - Prophylaxis, PrEP). To better understand the complexity of factors pushing people to relocate and the perception of stigma in previous places of residence, data will be collected through questionnaires; in-depth interviews with both HIV-positive gay - men of each generation and relevant stakeholders/policy-makers; and archival work to collect HIV-prevention campaigns, public health information and media news and reports among others. By shedding light on the dynamics of stigmatization still - affecting HIV-positive gay men, the research project will provides an evidence base for policy makers and service providers in order to make their intervention for the well-being of HIV-positive gay men more effective. - - 2020-02-29, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - HIVGAYM - - - H2020-MSCA-IF-2016 - - - 747110 - - - - - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - - - EUR 195 454,80 - - - Photoacoustic and fluorescence imaging platform for biosensing applications: An innovative approach for the study of disease-related biomarkers - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - In this Marie Skłodowska-Curie Fellowship (Photosense), I will design a photoacoustic and fluorescence imaging platform for the sensing of disease-related biomarkers, using conjunction rare-earth upconversion nanophosphors - (UCNPs) with organic dyes to form kinds of nanoprobes. By incorporating UCNPs and dyes, I aim to efficiently develop a series of organic and inorganic hybrid nanoprobes. The fluctuations in the concentration of disease-related biomarkers can be - monitored by fluorescence and photoacoustic signals simultaneously. Furthermore, this strategy can be easily expanded to detect different biomarkers by tuning and modifying the UCNPs and organic dyes pairs. I will apply my knowledge in multimodal - imaging and nanoparticle design and carry out these exciting tasks in the labs of Prof Molly Stevens at Imperial College London (ICL), exploiting her research programme’s expertise in nanomaterial-based components in biosensing technologies. My - Fellowship will be best executed in The Stevens Group (2016 Clemson Award for Basic Research/2014 Research Group of the Year) based on their world-class technological knowhow in designing such systems to yield the best outputs from Photosense. - - 2019-08-09, ongoing project - - - 2017-08-10 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - Photosense - - - H2020-MSCA-IF-2016 - - - 747206 - - - - - BOURNEMOUTH UNIVERSITY - - - EUR 195 454,80 - - - Media Literacy for Unaccompanied Refugee Youth - A Path to Integration - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - According to Eurostat, 2015 saw 90,000 unaccompanied minor asylum seekers register in the EU. Refugee children pose considerable policy challenges: their integration in Europe is of utmost importance. Studies show that while - refugee children have IT competences, they lack the ability to make critical media choices, and make informed decisions regarding their well-being. This project builds on the IT knowledge of young refugees in order to further their integration by - developing media literacy pedagogic tools. Media literacy education is essential for empowering citizenship, for gaining skills to become drivers of economic growth, and not least to prevent radicalization. Media literacy, a necessary aspect of - lifelong learning, enables young people to participate civically, to overcome disadvantage and to represent marginalized and missing voices. For developing these pedagogic tools, the Fellow will first research how unaccompanied minor refugees use - digital technology and social media through fieldwork carried out in 3 EU countries. In the second research phase, the Fellow will conduct participatory action research (PAR) in collaboration with an NGO which specializes in PAR with refugee youth. - These results will be used to design teaching materials for youth workers and teachers. The project is unique because it brings together the disciplines of education, media literacy and migration studies for offering solutions to a matter of pressing - urgency: the integration of unaccompanied minor refugees. This project will serve to widen the professional horizon of the Fellow. She will acquire specific research skills (digital ethnography, participant action research, educational tools design) - and transferable skills (PhD supervision, leadership, editorial skills, managing large-scale events). The project will lay the foundations for the Fellow's long-term career goals, and she will be propelled to the forefront of media literacy research. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - MedLitRefYouth - - - H2020-MSCA-IF-2016 - - - 747083 - - - - - CENTRO DE CIENCIAS DO MAR DO ALGARVE - - - EUR 160 635,60 - - - Integrating conspecific odors into tilapia reproductive behaviour - - - EUR 160 635,60 - - - Portugal - - - Research Organisations - - The aim of FISHODOR is to establish the identity of neural network components of the recently discovered tilapia reproductive pheromone. It will identify pheromone olfactory receptor(s) and their intracellular transduction - pathways thereby increasing our understanding of olfactory perception and signal integration of fish pheromones. The project will determine the neuronal cell type (i.e. ciliated, microvillous or crypt-type olfactory receptor neurons) detecting the - pheromone, it will establish the transduction pathways (i.e. AC/cAMP or PLC/IP3) involved in its olfactory detection and will identify the olfactory receptor(s) that binds the pheromone. If enough time is available it will attempt to map the neuronal - network involved in the neuroendocrine response. The combination of electrophysiology, transcriptomics and molecular biology will bring high degree of novelty to explain the mechanism of action of olfactory receptor and neuronal signal integration. - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Portugal - - - FISHODOR - - - H2020-MSCA-IF-2016 - - - 746507 - - - - - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - - - EUR 195 454,80 - - - Highly symmetric partial linear spaces - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The candidate proposes to investigate certain highly symmetric finite partial linear spaces using methods from combinatorics and group theory. A partial linear space consists of a set of points and a set of subsets of points - called lines for which each pair of points lies on at most one line, and each line contains at least two points. Both linear spaces and simple undirected graphs are examples of partial linear spaces. For a class of graphs X, a graph G is - X-homogeneous if any isomorphism between induced subgraphs of G that are isomorphic to a member of X can be lifted to an automorphism of the entire graph. This definition can naturally be extended to partial linear spaces for any class of partial - linear spaces X. The candidate has two long-term research goals. The first is to understand X-homogeneous partial linear spaces S where X is the class of connected partial linear spaces (possibly with bounded size). This leads to two main research - objectives. Objective 1 is to focus on the case when S is not a graph or a linear space, where nothing is yet known. Objective 2 is to continue her work on the case when S is a graph and the members of X have bounded size. The second long-term goal - of the candidate is to understand partial linear spaces admitting automorphism groups of low rank, which again leads to two main research objectives. Objective 3 is to complete the classification of the primitive permutation groups of rank at most 5. - Objective 4 is to use this classification to investigate certain partial linear spaces with rank 4 automorphism groups. These four objectives will enhance the expertise of the mathematical community. They will also lay the foundations for a future - programme of research for the candidate and enable her to obtain a permanent academic position. - - 2019-10-01, ongoing project - - - 2017-10-02 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - HSPLS - - - H2020-MSCA-IF-2016 - - - 746889 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 185 076 - - - Synergistic Resistive Switching of Perovskite and Silicon Carbide materials for Advanced ReRAM micro Devices - - - EUR 185 076 - - - France - - - Research Organisations - - Perovskite oxides are one of the most promising materials for developing new ReRAM devices, because they show a Resistive Switching (RS) behaviour and multilevel (ML) storage properties through reversible nanoionics redox - phenomena. However, several challenges remain to be addressed before introducing them in the emerging memories market. From a material point of view, it is still unclear how to tune and control the mass transport properties at the nanoscale to get - the best resistive switch response. From a device point of view, the development of new heterostructures thermally and chemically stable and compatible with the microelectronics technology is required. The ‘PerovSiC’ project combines synergistically - perovskite and carbide materials to overcome the current constraints. Starting from the recent breakthroughs of the hosting group, the project focuses on understanding the RS behaviour in perovskites using physical and chemical cutting-edge - characterization methods. Further, computational modeling will allow improving the RS process in the new carbide-based heterostructures. The final optimized configuration will be integrated in a highly stable ML ReRAM device. The results of the - project will lead to unexpected breakthroughs for neuromorphic computation, memories and logic devices. The multidisciplinary approach proposed will allow the researcher candidate gaining a deep understanding and specialisation in material science - - acquiring new competences in advanced techniques, such as XPEEM and operando Raman - and in Key Enabling Technologies, such as micro-technology. Moreover, the collaboration with the ENSC-Lille and the Institute Néel will complement the researcher’s - training giving her unique skills in IEDP-ToF-SIMS and synchrotron measurements. Therefore, planned research and training activities in the ‘PerovSiC’ project will re-enforce a position of professional maturity in research and will provide the - researcher new career perspectives. - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - PerovSiC - - - H2020-MSCA-IF-2016 - - - 746648 - - - - - KING'S COLLEGE LONDON - - - EUR 183 454,80 - - - Race, Church, and Colonial Government in the Atlantic: the case of Angola in the age of Enlightenment - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - ATLANTIC_ANGOLA seeks to address the issue of race by analyzing its intersections with religion/church and colonial government in Angola in the second half of the 18th-century/beginning of the 19th century. Being the main - provider of slaves to Brazil, Angola had a significant role for the economic success of the Portuguese South American colony, but also in the broader context of the Portuguese empire, due its privileged geographic position in the way between Asia and - Brazil. That explains the increasing attention it started to receive from the Portuguese Crown after c. 1750. The aim of ATLANTIC_ANGOLA is to understand the role of the Catholic Church in disciplining and controlling the population, and instilling - ideas of racial difference. The project hypothesis is that at least part of the population resisted the disciplining aims of the rulers. That resistance took different forms, but the result was the constitution of a creolized society, mainly in the - city of Luanda and its hinterland. The project will contribute to the discussion of the relations between races and perceptions of the “other” in the context of the Portuguese empire. Doing so, ATLANTIC_ANGOLA proposes a path-breaking approach to - problems still understudied concerning the history of European colonization of Africa before the 19th century. It will help to develop a better understanding of the historical dynamics of the relations between Europe and Africa over the longue durée. - It will also contribute to the historical explanation of the long-term effects of the colonization and the formation of the post-colonial societies, but also to the perception both of the Europeans towards Africa and Africans, and those towards - Europe. As to the more tangible outcomes of this project, they include 2 books, 3 articles in major peer-reviewed journals, 1 international conference, a talk series, and the setting-up of an online project. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ATLANTIC_ANGOLA - - - H2020-MSCA-IF-2016 - - - 746581 - - - - - INSTITUTO DE BIOLOGIA MOLECULAR E CELULAR-IBMC - - - EUR 148 635,60 - - - Investigating how anaphase chromosomal motion is generated during mitosis and meiosis - - - EUR 148 635,60 - - - Portugal - - - Research Organisations - - Cell division is a process essential for life. There are two types of cell division: meiosis and mitosis. Meiosis is a type of cell division specific to germ cells, allowing the formation of fertilisation-competent sperm and - eggs. Mitosis allows a single-celled fertilised egg to develop into a mature organism, and also allows tissues to be renewed. During each cell division, the cell must divide two copies of the genome equally between two daughter cells. Errors that - occur during this process in oocytes can lead to spontaneous abortion and birth defects, whilst errors occurring in somatic cells can lead to genetic instability, a hallmark of cancer. It is therefore essential to understand how this fundamental - process occurs. - - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Portugal - - - ChromoDrive - - - H2020-MSCA-IF-2016 - - - 746515 - - - - - KOC UNIVERSITY - - - EUR 157 734 - - - ANXIETY IN INTERNATIONAL POLITICS: MEDIATING EFFECTS OF NORMS - - - EUR 157 734 - - - Turkey - - - Higher or Secondary Education Establishments - - This interdisciplinary research project examines how anxiety impacts individual –level political attitudes toward international issues, and in turn how prevalence of anxiety interacts with nativist and cosmopolitan norms in - shaping international political attitudes. Bridging the fields of International Relations (IR), Psychology, and Philosophy, the research project will contribute to the distinct but related literatures on ontological security, emotions, and norms in - IR with a systematic analysis of anxiety. In its outgoing phase at the University of British Columbia, the research will focus on the development of a novel conceptual/ analytical framework linking anxiety, norms, narratives and international - political attitudes drawing primarily on existentialist philosophy and terror management theory in psychology. In the second phase at University of Columbia and the third phase at Koc University, the research will derive comparative cross-cultural - findings from experimental analyses conducted with university students at UBC in the outgoing phase and at Koc University (KU) in the reintegration phase. - - 2019-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Turkey - - - ANXINT - - - H2020-MSCA-IF-2016 - - - 746155 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 158 121,60 - - - Reconstructing the origins of animal multicellularity using experimental evolution - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - All living animals are descended from a single-celled ancestor. Understanding how this ancestor became the first multicellular animal remains a major challenge in the field of evolutionary biology. Phylogenomic analyses have - shown that animals are closely related to three unicellular lineages: choanoflagellates, filastereans and ichthyosporeans, altogether forming the Holozoa clade. Genetic and phenotypic studies have shown that the filasterean Capsaspora owczarzaki can - under specific growth conditions form transient multicellular aggregates. However, why is this multicellularity only transient? What are the genetic and phenotypic requirements for its emergence and stabilization? And what is the role of the actin - cytoskeleton in this transition? Indeed the actin cytoskeleton is known for its pivotal role for cell coordination and morphology, which must play a role in evolution of multicellularity. To address these questions, we will use the C. owczarzaki as a - model organism. We will combine cell biology, genomics and experimental evolution to unravel multicellularity emergence and stabilization. Specifically, we will aim to obtain evolved mutants showing excessive and more stable multicellular behaviour - of C. owczarzaki using long-term experimental evolution. Such evolved strains would unravel how multicellularity emerged and stabilized. In addition, using random mutagenesis screen, we aim to identify mutants unable to form multicellular aggregates. - Such mutants would reveal the minimum genetic requirements for such a transition. Finally, we will take advantage of recently developed genetic tools in C. owczarzaki to study the actin cytoskeleton during the cell cycle. Our results could reveal how - the first multicellular ancestor of animals appeared from a genetic and cellular perspective, and, how cell fate specification was established during evolution. Results generated on this fellowship will be relevant to evolutionary, cell and - developmental biologists. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - MULTICELLEXPEVO - - - H2020-MSCA-IF-2016 - - - 746044 - - - - - THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS - - - EUR 195 454,80 - - - Photoexcitation Dynamics and Direct Monitoring of Photovoltaic Processes of Solid-State Hybrid Organic-Inorganic Perovskite Solar Cells - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Abundant, cheap and clean source of energy is fundamental to preserve global environment and sustained economic growth. Solar energy is considered as the ultimate solution in this regard. Among the three generations of solar - cells developed with this objective, hybrid organic-inorganic perovskite solar cells with demonstrated power conversion efficiency (PCE) of over 22 % have bagged the greatest attention. Despite the impressive PCE, lower cost and facile processing - opportunities for hybrid perovskite solar cells, their commercialization is not yet realized; poor stability, lack of robustness to subtle variations in processing, and Pb toxicity being the bottlenecks. We take up the view that pursuing fundamental - understanding of the photophysics and photovoltaic process of these highly efficient lead halide perovskites can contribute to tackle their instability issue and also to the development of Pb free organic-inorganic halide perovskites with analogous - optical and photovoltaic performance to that of former, expediting their market entry. Apart from photovoltaic sector, the fundamental knowledge evolved through this project is expected to have direct impact on the fabrication of high performing - photodetectors, lasers, and light emitting devices based on hybrid perovskite materials. This interdisciplinary project lying at the interface of material science, physics and chemistry is expected to bring a breakthrough in perovskite solar cell - research arena.The proposed project will utilize the applicant’s expertise in the fabrication of high efficient organic and perovskite solar cells in combination with world leading scientist Prof. Ifor Samuel’s expertise on photophysics aspects of - thin film solar cells and the excellent infrastructure facilities at the host institution. In implementing this ambitious project, I will gain expertise on the photophysics and photovoltaic processes (under real operating conditions) of hybrid - perovskite thin films and solar cells. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - PHOTOPEROVSKITES - - - H2020-MSCA-IF-2016 - - - 745776 - - - - - CARDIFF UNIVERSITY - - - EUR 183 454,80 - - - Self-healing geological construction materials and structures - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Geological materials are used in significant quantities for construction purposes, structurally and for cladding, but are subject to damage, deformation and deterioration through natural weathering processes in combination - with the stress state induced in service. As a consequence, structural performance can be reduced, durability is compromised and there may be aesthetic or heritage issues with regard to preservation of the original structural form. Currently, such - issues are addressed either through initial overdesign, implementation of maintenance programmes, or both. The proposal seeks to explore the potential for providing such materials with the ability to self-heal – to automatically respond to damage or - deterioration, instigating a healing process that restores or even enhances the desirable structural or aesthetic properties. Such technology will take inspiration from, and work in parallel with, current research into self-healing in cementitious, - polymeric and other engineering materials. - - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - GEOHEAL - - - H2020-MSCA-IF-2016 - - - 745891 - - - - - THE UNIVERSITY OF SHEFFIELD - - - EUR 183 454,80 - - - High Attenuation Recycling Materials as sustainable barriers for waste disposal sites - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The need to minimize the amount and foster the safe treatment of waste, and thereby reduce the risk of contamination; emphasises the importance of promoting technologies which are environmentally sound with products suitable - for re-use/recycling. This project establishes a laboratory experimental study to determine the performance of clay mixed with construction and biomass plant waste (fine recycled aggregates, FRA, and/or biomass bottom ashes, BBA) as materials for the - enhanced attenuation of contaminants in landfill leachate. The aim is to (1) evaluate the contaminant attenuation capacity of these mixtures for different conditions, (2) develop design guidelines to construct barriers for waste containment systems - and similar applications, and (3) interpret their performance using numerical modelling tools. Column experiments where landfill leachate is passed through different waste:clay mixtures will be run in a state-of-the-art centrifuge facility which - simulates realistic times, pressures and temperatures of landfill field conditions. The geochemistry of the column pore water and material residues after permeation with leachate will be examined to deduce the processes responsible for pollutant - removal and retention. After permeation with landfill leachate, the effects of exposure of these barriers to an aggressive acid environment, rainfall infiltration and rising water table will be studied. The concept will be applicable for barrier - design at other waste disposal facilities. The results will provide a novel and timely improvement which addresses the problem of managing the vast amounts of industrial residues such as FRA and BBA. Instead of disposal these will be re-used/recycled - as an additive in host clay for building contaminant barriers, thus also conserving natural resources (clay and other man-made barrier materials). It will also provide an effective and more environmentally sustainable basis to control landfill - pollution risks. - - 2020-02-22, Grant Agreement signed - - - 2018-02-23 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - HARM - - - H2020-MSCA-IF-2016 - - - 743880 - - - - - BCBL BASQUE CENTER ON COGNITION BRAIN AND LANGUAGE - - - EUR 158 121,60 - - - Cognition, ageing, and bilingualism: Investigating age-related changes in bilingual language switching and use. - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - Older adults show difficulties with bilingual language processing and switching compared to younger adults. For example, they need more time to switch between languages and show more cross-language intrusions. Language - problems have not only been found for healthy older adults, but also in patients with dementia and Parkinson’s disease. Language deterioration could be used as an early disease marker to improve diagnosis. However, the exact nature of bilingual - language problems in healthy older adults needs to be studied first. Besides language deficits, older age has also been associated with deficits on executive control tasks (e.g., inhibition and switching tasks). While executive control is argued to - be needed during (bilingual) language production, it is unclear how the two relate in older adults. Although some studies have found similarities between language and cognitive control, others found deviating patterns. - - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - CAB - - - H2020-MSCA-IF-2016 - - - 743691 - - - - - Eidgenössische Technische Hochschule Zürich - - - EUR 187 419,60 - - - Properties across dimensions: an atomistic computational study of bismuth ferrite surfaces and nanocrystals - - - EUR 187 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - Bismuth ferrite (BFO) is one of the few multiferroic materials at room temperature. It is of interest for use in memory elements, spintronic and photovoltaic systems, to name but a few. In all applications, the use of BFO thin - films and nanoparticles is being greatly investigated, due to their greater fatigue resistance and larger polarization at modest electric fields with respect to the bulk. However, reducing the dimensionality of BFO can lead to surprising and so far - unexplained behaviour. For example, recent experiments have reported the existence of a surface “skin” above bulk-truncated BFO, with different lattice parameters and phase transitions than the underlying bulk. This surface skin layer exhibits - strikingly different properties from the bulk, since it is ferroelastically and ferroelectrically dead. It is thus of paramount importance, for practical applications of BFO, to understand how 2D structures (like thin films) and 1D structures (like - nanocrystals) differ in their multiferroic behaviour from the relatively well understood bulk phase. Since surfaces are dominant in these two classes of systems, a good atomistic understanding of low-energy surfaces and their stability in the - environment is needed. Thus, we propose a two-year project with the overall aim of studying the atomistic structure and the magnetic and polarization properties of BFO thin films and nanocrystals using using ab initio methods (density functional - theory with ab initio thermodynamics). - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - BFO-Surf - - - H2020-MSCA-IF-2016 - - - 744027 - - - - - MEDICAL RESEARCH COUNCIL - - - EUR 195 454,80 - - - Assessing Causal Relationships of Oscillatory Neural Activity Mediating Speech - - - EUR 195 454,80 - - - United Kingdom - - - Research Organisations - - Neural oscillations, rhythmic fluctuations in the excitability of neuronal populations, align their phase to the rhythm of speech and this mechanism, called phase entrainment, has been associated with successful perception of - connected speech. However, a causal role of phase entrainment for speech comprehension has not yet been shown which leaves the underlying mechanisms unclear, and fails to specify the relevance of neural oscillations for hearing or language impaired - individuals. In the proposed research, we will use a novel brain stimulation technique, transcranial alternating current stimulation (tACS) to selectively alter neural oscillations. By manipulating neural phase entrainment to speech with tACS we can, - for the first time, provide decisive evidence concerning whether phase entrainment and speech comprehension are causally linked: If a modulation of phase entrainment leads to changes in speech perception and comprehension we can conclude that the - former causally influences the latter. In a preliminary experiment, combining tACS with functional magnetic imaging (fMRI), we will determine the optimal tACS electrode montage to modulate neural activity in speech-specific brain regions (in the - superior temporal gyrus). Using this setup in a behavioural task, tACS can be applied at different phase-lags in relation to rhythmic speech sequences. Critically, we expect perception of these stimuli to depend on the phase relation between tACS and - speech rhythm, as a consequence of the manipulation of phase entrainment by tACS. Our study will thus provide important and novel evidence for a causal role of phase entrainment for speech perception and comprehension. In turn this might suggest new - methods for enhancing speech perception in populations with hearing or language impairment. - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ACRONAM-Speech - - - H2020-MSCA-IF-2016 - - - 743482 - - - - - THE UNIVERSITY OF NOTTINGHAM - - - EUR 183 454,80 - - - Advanced modelling of ultrasonic wave interaction with damage for enhanced failure identification technologies in industrial composite structures - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The EU is a world leader in the transport industry, with the aeronautical sector alone providing more than 500,000 jobs and generating a turnover of EUR 140 billion annually. Development of structural safety technologies have - always been of paramount importance for Europe. With regard to the aeronautical sector, approximately 1.3 billion passengers fly around the globe every year, rendering aviation safety a major societal challenge worldwide. Flightpath 2050 sets out a - vision for a future aerospace industry placing airworthiness at the heart of technology developments in order to keep Europe competitive in this strategically important global industry. - - 2020-02-24, Grant Agreement signed - - - 2018-02-25 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - UltraSafe - - - H2020-MSCA-IF-2016 - - - 741284 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 158 121,60 - - - The effect of seagrass bed habitat quality on selected ecosystem services - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - Seagrass meadows serve many important ecosystem functions and services in coastal waters. Most notably, through their role as nursery and feeding areas they support a great abundance and diversity of fish and invertebrates, - making them important for fisheries and local economies. In spite of their ecological and socio-economic importance, seagrass meadows worldwide have been experiencing declines and habitat degradation through fundamental changes in their structural - complexity. Currently only limited knowledge exists of how these configurational changes influence the functioning and the ecological and cultural services provided by seagrasses. Through a combination of ecological and social data collection methods - that include citizen science, PIONEER takes an interdisciplinary approach to assess how changes in the environmental status of Posidonia oceanica ecosystems affect important ecosystem services for both marine biota and humans in the Balearic Islands, - namely (i) seagrass nursery function for juvenile fish, (ii) food provision capacity for adult fish and fishers’ perception of the recreational fishing sector. PIONEER provides relevant and timely information for the implementation of the EU Marine - Strategy Framework Directive, which aims to achieve Good Environmental Status in all water bodies across EU member states by 2020. Findings from this project will be relevant for both conservation and management of these habitats; dissemination of - results will target scientists, governmental and non-governmental authorities and end-users of seagrass habitats. The fellowship contributes to the candidate’s career development mainly through the acquisition of advanced skills in ecological and - social sciences that will provide a notable improvement to her multidisciplinary background and diversification of research expertise, as well as enlarging the international network of professional contacts to southern Europe. - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - PIONEER - - - H2020-MSCA-IF-2016 - - - 740481 - - - - - THE HEBREW UNIVERSITY OF JERUSALEM - - - EUR 170 509,20 - - - Statistical learning and second language acquisition: individual differences and neurobiological underpinning. - - - EUR 170 509,20 - - - Israel - - - Higher or Secondary Education Establishments - - Consider a Libyan immigrating to Italy, or a businessman relocated in Tel Aviv. Reading in a second language would be a prerequisite for a successful assimilation in a new country. How is this formidable task achieved? The - overarching goal of INDIV-STAT is to provide a deep understanding of second language (L2) literacy acquisition by tying individual abilities in language learning to the domain-general capacity to detect, store, and use statistical regularities in the - input. The project brings together (a) behavioral research on individual differences in statistical learning (SL), and (b) a controlled investigation of the neurobiological basis of SL capacities. It launches a set of mutually informative research - axes: First, given the large individual differences in L2 learning, we develop psychometrically reliable behavioral tests of individuals’ capacities to extract regularities in the visual and auditory modalities, to better measure behavioral SL, and - serve the subsequent experimental packages. Second, we use EEG and MEG, targeting the what, where, and how of SL, probing its neural underpinning. By obtaining reliable brain signatures of the neural dynamics associated with SL we will be able to - examine the detection of language-related regularities for print and speech during L2 learning. Third, we launch a series of behavioral experiments to investigate the link between individual capacities in SL, and the ease or difficulty of L2 literacy - acquisition. Finally, we evaluate whether we can experimentally enhance the process of acquiring literacy in L2 by enhancing participants’ sensitivity to regularities. The project will offer an empirically-validated neurobiological theory of how the - specific statistical properties of a language are assimilated during L2 literacy acquisition, addressing also individual differences in learning capacity. This will have important educational and societally implications. - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Israel - - - INDIV-STAT - - - H2020-MSCA-IF-2016 - - - 743528 - - - - - FONDAZIONE EDMUND MACH - - - EUR 176 203,80 - - - GUT biota indices: a new tool for WILD animal conservation - - - EUR 176 203,80 - - - Italy - - - Higher or Secondary Education Establishments - - Calls to stem biodiversity loss have generally focussed on the plight of charismatic vertebrates (mammals, birds, fish, amphibians) and to some extent, insects (like butterflies). However, although the abundance and diversity - of microbial and helminth communities inhabiting the gastrointestinal tract have been demonstrated of critical importance to health in both humans and non-human animals, this microbiodiversity has rarely been considered within a conservation - framework. Using recently collected fecal samples from two free-ranging tropical non-human primate species with contrasting ecological parameters, WILDGUT proposes a multi-disciplinary approach to investigate the four-way interplay between habitat - changes, host species, and gut micro- and macro-parasites in natural environments. The results will lead to a better understanding of the impact of human activities on microbiodiversity, and whether such changes could have an effect on wildlife - health, and ultimately to a species’ conservation status. Thus, the project will explore whether the comparison of gut microbiota and helminth community diversity, functions and interaction between intact and degraded habitats can be used to develop - new indices to estimate host health and informing conservation strategies. - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Italy - - - WILDGUT - - - H2020-MSCA-IF-2016 - - - 752399 - - - - - KARLSRUHER INSTITUT FUER TECHNOLOGIE - KARLSRUHER INSTITUT FUER TECHNOLOGIE - - - EUR 150 000 - - - A custom lock chip for compact NMR - - - EUR 150 000 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Nuclear magnetic resonance is an important chemical analysis method, because of its inherent chemical specificity, its versatility to extract molecular information, and its absolute accuracy. The market has been dominated by - large superconducting NMR magnets with price tags of many 100k €. The emergence of less expensive low field compact (tabletop and portable) NMR spectrometers, based on the use of permanent magnets, with price tags around a factor of 10 lower than - superconducting magnets, brings a drastically lower cost-of-ownership, and the significantly lower need for external support, maintenance, and lack of liquid Helium, which is opening up new applications and huge new markets for NMR. - - 2018-09-30, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Germany - - - LockChip - - - ERC-2016-PoC - - - 741728 - - - - - UNIVERSITAET STUTTGART - UNIVERSITAET STUTTGART - - - EUR 150 000 - - - NMR-based Sensor Technology at Nanoscale - - - EUR 150 000 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Nuclear Magnetic Resonance (NMR) spectrometry is the most widely used method in the spectrometry market. With applications in various areas such as geo exploration, material quality control, drug development, and biomedical - imaging, NMR provides rich spectroscopic information of the structure for material analyses. Therefore, for advancing human health and science, NMR spectrometry and also microfluidics are widely adopted technologies in studying biological processes - and thus utilised in many biomedical applications. However, given its low sensitivity, the technique is only applicable to large specimens. This proof-of-concept project develops novel atomic-size defect centres in diamond, which are superior to the - current state-of-the-art magnetic field sensors in terms of spatial resolution, sensitivity and rugged design. Initial tests with single sensing defects confirm estimates on the achievable spatial resolution down to a few nanometers and reduction of - volumetric sensitivity by factor of 108 as compared to the existing technologies. Through achieving this level, we are able to bring the full functionality and integration of NMR, i.e. molecular specificity to micro analytics. Therefore, the - improvement of NMR sensitivity and the development of nanoscale NMR imaging, promises revolutionary impacts on the areas of bioscience and spectrometry technology, which in turn enables new applications in areas such as nanotechnology and - bioanalytics. In this project, we’ll (1) demonstrate integration of a diamond-based NMR sensor into a microfluidic device and in magnetic storage system. To best prepare for the post-PoC commercialisation we’ll (2) test the NMR device in real-life - industrial application, i.e. in characterization of hard-dick’s write-head. Moreover, we’ll also (3) carry out pre-commercialisation and networking activities, and (4) plan for the commercialisation of the novel NMR microfluidic sensor technology. - - 2018-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Germany - - - NMRNTECH - - - ERC-2016-PoC - - - 727575 - - - - - KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW - KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW - - - EUR 147 500 - - - Pharmacological safety testing in human adult stem cell-derived organoids - - - EUR 147 500 - - - Netherlands - Netherlands - - - Research Organisations - Research Organisations - - Toxicology and pharmacology assays are crucial pillars of modern drug development. They are essential to understand how tissues such as intestine and liver take up and degrade pharmaceutically active compounds. Due to the lack - of suitable in vitro systems, these assays are carried out in experimental animals. This practice increases cost and development time but also creates significant ethical issues. - - - 2018-09-30, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Netherlands - - - TOXANOID - - - ERC-2016-PoC - - - 737600 - - - - - AALTO-KORKEAKOULUSAATIO - AALTO-KORKEAKOULUSAATIO - - - EUR 149 858 - - - Graphene Tunneling Accelerometer - - - EUR 149 858 - - - Finland - Finland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The commercialization of existing tunneling accelerometers is hindered by their complex fabrication and long-term instability. Based on our results and expertise from the currently running ERC project, we propose an innovative - design using graphene as the game-changing material for tunneling accelerometers. - - 2018-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Finland - - - GraTA - - - ERC-2016-PoC - - - 727542 - - - - - UNIVERSITY OF EAST ANGLIA - UNIVERSITY OF EAST ANGLIA - - - EUR 149 115 - - - Highly Efficient Photoemitters for Light-Emitting Diodes Based on Intramolecular Rotation - - - EUR 149 115 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - "We have discovered a new class of photo- and electroluminescent complexes which are suitable for incorporation into organic light emitting diodes (OLEDs) and which give up to 100% internal quantum yield. The new compounds are - particularly suitable for the fabrication of OLEDs via cheap solution-processing techniques and have so far reached 27% external quantum efficiency, a record for any solution-processed device. The new complexes have a linear, rotationally flexible - structure, and it is this rotation that allows 100% of the excitation energy to be harvested, by a new emission mechanism (“rotationally accessed spin-state inversion”, RASI). OLEDs are widely used as flat-screen displays (TVs, smartphones), a - multi-billion dollar market worldwide. The industry-leading emitters are based on complexes of iridium, one of the rarest elements on earth. Our emitters are compounds of copper, silver and gold, suitable as “slot-in” replacements of iridium. IPR is - protected by two UK and one PCT World patent applications. The key discovery is that in certain types of coordination complexes based on carbene ligands the excited singlet state sinks below the excited triplet state during molecular rotation. To our - knowledge this is the first realization of "spin-state inverted" materials, until now discussed only as a theoretical concept. The result is efficient, very fast light harvesting with highly desirable short (sub-microsecond) excitation lifetimes, - leading to high display brightness (in prototypes 20 times brighter than a HD TV screen), with potential lighting applications." - - 2018-12-31, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - ROLEDS - - - ERC-2016-PoC - - - 754615 - - - - - FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA) - - - EUR 158 121,60 - - - FRAGMENT screening from advanced-sampling molecular dynamics simulations on a proteOME scale. - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - In Fragment-Based Lead Discovery (FBLD) highly sensitive biochemical and biophysical screening technologies are used to detect the low-affinity binding of low-molecular-weight compounds (the so-called fragments) to biological - targets that are involved in pathophysiological processes. Knowledge of the molecular interactions between fragment hit(s) and the target protein allows the rational generation of high-quality leads for drug development. Thus, high-resolution (e.g. - X-ray crystallography) and relatively high-throughput structure determination technologies are key to this approach but they can become a limiting factor for both technical and economical reasons. As a matter of fact, when the experimental - characterization of binding mode fails, the success rate of FBLD approaches drastically drops. To overcome current limitations in FLBD, here we propose the development of a computational framework based on advanced-sampling molecular dynamics - simulations to map the binding of fragments to protein surfaces on the proteome scale---thus generating the Fragmentome Altas. For each individual target this will allow to: a) systematically identify fragments binding to protein surfaces and cryptic - pockets; b) reconstruct the mechanism of binding with atomistic spatiotemporal resolution; c) characterize the molecular determinants of affinity and kinetics in fragment-protein complexes. This insight is fundamental for optimizing and evolving - fragments to lead compounds with desired thermodynamics and kinetics features. To date, neither experimental nor computational approaches can provide such information at affordable costs while maintaining the high throughput needed for screening - campaigns. The successful implementation of this ambitious project lies in the unique combination of expertise of its participants, and it will allow a novel state-of-the-art for modern drug discovery to be established. The Fragentome Atlas will be a - freely accessible on-line server. - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - FRAGMENTOME - - - H2020-MSCA-IF-2016 - - - 752415 - - - - - UNIVERSITY COLLEGE LONDON - - - EUR 183 454,80 - - - Efferent modulation of auditory sensitivity in mosquitoes: From auditory transduction to swarming behaviour - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Hearing in mosquitoes is crucial for mating partner recognition. Within mating swarms, males hear the wing beat of females and chase them to copulate. Despite the importance of this behaviour, very little is known about the - molecular mechanisms involved. I and my co-workers have recently discovered an auditory efferent system innervating the mosquito hearing organ, the Johnston's Organ (JO) that releases the biogenic amines octopamine and serotonin and modulates the - auditory function. However, we still do not know how this efferent system modulates hearing in the context of swarming. - - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - NEURO-SWARM - - - H2020-MSCA-IF-2016 - - - 752472 - - - - - INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE - - - EUR 171 349,20 - - - Rol of obligate bacterial symbiosis in the diversification of a globally distributed aphid genus - - - EUR 171 349,20 - - - France - - - Research Organisations - - Plant-feeding insects represent a significant part of earth biodiversity but also encompass many plant pests that cause major losses to agricultural crops. One key factor in their evolutionary success probably resides in the - mutualistic associations they have established with bacteria that reside in their cells. These endosymbionts metabolize some of the nutrients lacking in their host diet and can be essential for successfully shifting to new ecological niches. However, - intracellular lifestyle also often results in severe genomic erosion for endosymbionts that limits their metabolic versatility and in fine affects their host adaptive potential. In this project we aim at deciphering the role of bacterial - endosymbiosis in the long-term evolution of plant-feeding insects. The main question we want to address is whether the evolution of obligate bacterial endosymbionts played a significant role in the diversification (speciation and extinction) of their - hosts. Using the genome sequences of the main bacterial endosymbionts associated with a globally distributed aphid genus, we will: 1) reconstruct the history of aphid/symbiont associations by conducting phylogenomic analyses; 2) identify the - footprint of selection and genetic drift in bacterial genomes by comparing patterns of molecular evolution within and between symbiotic bacterial lineages; 3) illuminate how changes in the endosymbiont community metabolic capabilities have - accompanied aphids evolutionary transitions (host plant shifts, climatic tolerance, rates of speciation) using phylogenetic comparative methods. Using the data from an ongoing large sequencing project, this project will combine recent methods in - phylogenomics, metabolic network analyses and the study of macroevolutionary processes. With this fellowship, the applicant will lead an exciting and innovative multidisciplinary project, supervised by international experts in microbial evolutionary - genomics and insect macroevolution; this project will cre - - 2020-06-14, Grant Agreement signed - - - 2018-06-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - France - - - MicroPhan - - - H2020-MSCA-IF-2016 - - - 746189 - - - - - UNIVERSITEIT LEIDEN - UNIVERSITEIT LEIDEN - - - EUR 1 999 342 - - - Building an Evidence-Base for Reducing Gender Bias in Educational Pathways - - - EUR 1 999 342 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In 2012, the European Commission launched the campaign Science: It’s a girl thing!, aimed at encouraging women to choose research careers, as they are sorely underrepresented in science, technology, engineering, and - mathematics (STEM). Given that gender disparities in aptitude for specific fields are generally very small, highly gendered skewness in educational choices suggest pathways dictated by stereotypes rather than abilities, leaving valuable STEM talents - unused. - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - GirlsInScience - - - ERC-2016-COG - - - 726141 - - - - - Biologicke centrum AV CR, v. v. i. - Biologicke centrum AV CR, v. v. i. - - - EUR 2 000 000 - - - Insect Photoperiodic Timer - - - EUR 2 000 000 - - - Czech Republic - Czech Republic - - - Research Organisations - Research Organisations - - Daylength measuring devices such as the photoperiodic timer enable animals to anticipate and thus survive adverse seasons. This ability has contributed to the great success of insects living in temperate regions. Yet the basis - of photoperiodic sensing remains elusive, because of the lack of suitable genetic models expressing photoperiod-dependent seasonal phenotypes. We have developed the linden bug, Pyrrhocoris apterus, into a genetically tractable model with a robust, - photoperiod-dependent reproductive arrest (diapause). With the available tools, this insect has become ideal for deciphering the regulation of seasonality. The project has 3 clear and ambitious objectives: 1). Our goal is to define the molecular and - anatomical bases of the photoperiodic timer. To achieve this, we propose to identify photoperiodic timer genes, genes regulating input to the timer, and early output markers, through an RNA interference screen(s). To define the molecular mechanism of - the timer, we will employ genome editing to precisely alter properties of the key players. 2). Next, we will combine techniques of neuronal backfilling, in-vivo fluorescent reporters, and microsurgery to define the photoperiodic timer anatomically - and to examine its spatial relationship to the circadian clock in the insect brain. 3). We will exploit the great natural geographic variability of photoperiodic timing in P. apterus to explore its genetic basis. Genetic variants correlating with - phenotypic differences will be causally tested by genome editing within the original genetic backgrounds. Both the established and the innovative strategies provide a complementary approach to the first molecular characterization of the seasonal - photoperiodic timer in insects. The proposed research aspires to explain mechanisms underlying the critical physiological adaptation to changing seasons. Deciphering mechanisms underpinning widespread adaptation might bring general implications for - environment-friendly pest control. - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Czech Republic - - - InPhoTime - - - ERC-2016-COG - - - 726049 - - - - - JOHN INNES CENTRE - JOHN INNES CENTRE - - - EUR 2 162 500 - - - The role of the symplast in host-pathogen interactions – how does the symplastic, intercellular exchange of molecules regulate the outcomes of defence and infection? - - - EUR 2 162 500 - - - United Kingdom - United Kingdom - - - Research Organisations - Research Organisations - - Cell-to-cell communication is fundamental to multicellular organisms. The exchange of information and resources between cells and tissues enables co-ordination of responses to environmental and developmental signals. In - plants, the cytoplasm of adjacent cells is connected by plasma membrane-line pores called plasmodesmata (PD) that cross the cell wall, generating cytoplasmic continuity between cells and tissues. This interconnected cytoplasm is termed the symplast - and is unique to plants. In plants, growing evidence suggests that innate immune responses rely on regulation of symplastic connectivity. My group previously discovered that regulation of PD (whether they are open or closed) is critical for immune - responses. Further, we have shown that pathogens suppress host regulation of PD in an effort to maintain symplastic continuity between cells. We don’t know why the host regulates the symplast during defence: while data suggests that different defence - responses might differently exploit the symplast, we don’t understand how the symplast defines the success of a response. Similarly, we don’t know how a pathogen benefits from maintaining connectivity with surrounding host cells – is this to allow - the movement of molecules to suppress defence, or is it to optimise access to host resources? This programme will investigate the question of how the symplast contributes to defence and infection strategies. We aim to understand how these strategies - play out in an infection context. We will use experimental and computational approaches to generate models that allow us to predict the outcome of infection upon the basis of symplastic processes and PD regulation. Ultimately, this will create a - framework for novel strategies to enhance pathogen resistance. - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - INTERCELLAR - - - ERC-2016-COG - - - 725459 - - - - - KARLSRUHER INSTITUT FUER TECHNOLOGIE - KARLSRUHER INSTITUT FUER TECHNOLOGIE - - - EUR 1 975 813,75 - - - Preparing Cryptography for Modern Applications - - - EUR 1 975 813,75 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - "Cryptography currently faces fundamentally new challenges. Modern applications like Big Data or Cloud Computing require cryptographic methods that go far beyond secure communication. Such cryptographic methods have only been - invented in recent years: namely, since 2009, several unexpected and game-changing *new cryptographic building blocks* have been introduced. Most prominently, constructions of fully homomorphic encryption, code obfuscation, and multilinear maps have - been proposed. These constructions have opened the door to applications that were previously believed unattainable, such as the secure outsourcing of computations. - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - PREP-CRYPTO - - - ERC-2016-COG - - - 724307 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 596 500 - - - Planetary Interiors Constrained by Key Laboratory Experiments - - - EUR 1 596 500 - - - France - France - - - Research Organisations - Research Organisations - - The knowledge of interiors of rocky planets of our solar system (Mercury, Venus, Earth and Mars) is important for understanding their formation, present state, and evolution. The comprehension of differences and similarities - in the internal constitution and processes will shed a new light on the origin and evolution of the solar system. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - France - - - PICKLE - - - ERC-2016-COG - - - 724690 - - - - - UNIVERSITY COLLEGE LONDON - UNIVERSITY COLLEGE LONDON - - - EUR 1 999 806 - - - Carbon – Ice Composite Materials: Water Structure and Dynamics at the Carbon Interface - - - EUR 1 999 806 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Carbon and water in its various states of matter make up a substantial proportion of our Universe. The two materials are highly dissimilar with respect to their chemical and physical properties. Elemental carbon is even often - referred to as a hydrophobic, ‘water-hating’ material. Yet, the two materials often coexist and critical processes take place at the interface between these unlike chemical species. This includes the hydration shells of hydrophobic moieties in - biomolecules, clathrate hydrate materials where water molecules crystallise around hydrophobic guest species as well as icy comets which are often black due to the presence of carbon at their surfaces. - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - CARBONICE - - - ERC-2016-COG - - - 725271 - - - - - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - - - EUR 1 999 125 - - - Ribosome inhibition by nascent or antimicrobial peptides - - - EUR 1 999 125 - - - France - France - - - Research Organisations - Research Organisations - - During the translation of genetic information into protein by the ribosome, nascent peptides occasionally inhibit their own synthesis by interacting with the exit tunnel of the large ribosomal subunit. Known as nascent - chain-mediated translational arrest, this process depends primarily upon the amino acid sequence of the arrest peptide. However, it can also rely upon the sensing of a low molecular weight ligand by the ribosome nascent chain complex, explaining its - use for metabolite-dependent gene regulation in both bacteria and eukaryotes. Biochemical and structural studies of arrest peptides have yielded key insights into their mode of action, but their ability to sense different types of small molecules, - their impact as regulators of gene expression in nature and the precise molecular details behind the arrest process are still largely unexplored. - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - France - - - NascenTomiX - - - ERC-2016-COG - - - 724040 - - - - - UNIVERSITE DE LAUSANNE - UNIVERSITE DE LAUSANNE - - - EUR 1 499 966 - - - Plant cell wall communication and remodelling: the wall watchers. - - - EUR 1 499 966 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Plants, just like animals are highly developed multicellular organisms. In contrast to animal cells however, plant cells are surrounded by a rigid, carbohydrate-rich extracellular layer, the cell wall. This cell wall provides - plants with mechanic support and a dynamic chemical signalling and metabolic environment. To allow for cell expansion, cell division, coordinated tissue growth and interactions with the environment, the cell wall status constantly needs to be sensed - and modified. How plant cells perceive and signal their cell wall status is poorly understood. Here, I propose an integrated approach to uncover ligands for cell wall sensing receptors as well as their downstream signalling components. Specifically, - my project aims to identify the ligands for two genetically validated cell wall receptor families, using a chemical biology approach. Next, we will analyse and validate the mode of ligand-receptor interaction by combining protein X-ray - crystallography, quantitative biochemistry and reverse genetics in Arabidopsis. A detailed ligand-binding and receptor activation mechanism will allow us to specifically interfere with cell wall receptor function in vivo, and to assess their - biological relevance for cell wall structure and its chemical properties. Using atomic force microscopy, we will then test if the receptors are distributed uniformly at the membrane or whether they are arranged in complex 'sensosomes'. Finally, we - will characterize if plant cell wall receptors can directly act as mechanosensors. With defined receptor-ligand pairs and clear phenotypes at hand, we will try to uncover downstream signalling components for plant cell wall receptors and to validate - our atomic models in planta. My ultimate goal would be to design and test cell wall receptor agonists and antagonists, which will represent powerful tools to alter cell wall homoeostasis in Arabidopsis, and potentially in crops. - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Switzerland - - - WallWatchers - - - ERC-2016-STG - - - 716358 - - - - - ALBERT-LUDWIGS-UNIVERSITAET FREIBURG - ALBERT-LUDWIGS-UNIVERSITAET FREIBURG - - - EUR 1 499 219 - - - A Flexible Platform for the Application of SAM-dependent enzymes - - - EUR 1 499 219 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - AppSAM will unlock the synthetic capability of S-adenosyl¬methionine (SAM)-dependent methyltransferases and radical SAM enzymes for application in environmentally friendly and fully sustainable reactions. The biotechnological - application of these enzymes will provide access to chemo-, regio- and stereoselective methylations and alkylations, as well as to a wide range of complex rearrangement reactions that are currently not possible through traditional approaches. - Methylation reactions are of particular interest due to their importance in epigenetics, cancer metabolism and the development of novel pharmaceuticals. As chemical methylation methods often involve toxic compounds and rarely exhibit the desired - selectivity and specificity, there is an urgent need for new, environmentally friendly methodologies. - - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - AppSAM - - - ERC-2016-STG - - - 716966 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 871 250 - - - Shaping a European Scientific Scene : Alfonsine Astronomy - - - EUR 1 871 250 - - - France - France - - - Research Organisations - Research Organisations - - Alfonsine astronomy is arguably among the first European scientific achievements. It shaped a scene for actors like Regiomontanus or Copernicus. There is however little detailed historical analysis encompassing its development - in its full breadth. ALFA addresses this issue by studying tables, instruments, mathematical and theoretical texts in a methodologically innovative way relying on approaches from the history of manuscript cultures, history of mathematics, and history - of astronomy. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - France - - - ALFA - - - ERC-2016-COG - - - 723085 - - - - - UNIVERSITY OF DUNDEE - UNIVERSITY OF DUNDEE - - - EUR 1 444 081 - - - IMPACT OF DNA REPLICATION ON EPIGENETICS - - - EUR 1 444 081 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - During lineage propagation, cells must duplicate their genetic and epigenetic information to maintain cell identity. However, the mechanisms underlying the maintenance of epigenetic information in dividing cells remain largely unknown. - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - IDRE - - - ERC-2016-STG - - - 715127 - - - - - TECHNISCHE UNIVERSITEIT DELFT - TECHNISCHE UNIVERSITEIT DELFT - - - EUR 1 500 000 - - - Origins of Collective Motion in Active Biofluids - - - EUR 1 500 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The emergence of coherent behaviour is ubiquitous in the natural world and has long captivated biologists and physicists alike. One area of growing interest is the collective motion and synchronization arising within and - between simple motile organisms. My goal is to develop and use a novel experimental approach to unravel the origins of spontaneous coherent motion in three model systems of biofluids: (1) the synchronization of the two flagella of green algae - Chlamydomonas Rheinhardtii, (2) the metachronal wave in the cilia of protist Paramecium and (3) the collective motion of swimming microorganisms in active suspensions. Understanding the mechanisms leading to collective motion is of tremendous - importance because it is crucial to many biological processes such as mechanical signal transduction, embryonic development and biofilm formation. - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - ActiveBioFluids - - - ERC-2016-STG - - - 716712 - - - - - UNIVERSITY OF LIMERICK - UNIVERSITY OF LIMERICK - - - EUR 1 499 043,75 - - - Solar Energy Conversion without Solid State Architectures: Pushing the Boundaries of Photoconversion Efficiencies at Self-healing Photosensitiser Functionalised Soft Interfaces - - - EUR 1 499 043,75 - - - Ireland - Ireland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Innovations in solar energy conversion are required to meet humanity’s growing energy demand, while reducing reliance on fossil fuels. All solar energy conversion devices harvest light and then separate photoproducts, - minimising recombination. Normally charge separation takes place at the surface of nanostructured electrodes, often covered with photosensitiser molecules such as in dye-sensitised solar cells; DSSCs. However, the use solid state architectures made - from inorganic materials leads to high processing costs, occasionally the use of toxic materials and an inability to generate a large and significant source of energy due to manufacturing limitations. An alternative is to effect charge separation at - electrically polarised soft (immiscible water-oil) interfaces capable of driving charge transfer reactions and easily “dye-sensitised”. Photoproducts can be separated on either side of the soft interface based on their hydrophobicity or - hydrophilicity, minimising recombination. SOFT-PHOTOCONVERSION will explore if photoconversion efficiencies at soft interfaces can be improved to become competitive with current photoelectrochemical systems, such as DSSCs. To achieve this goal - innovative soft interface functionalisation strategies will be designed. To implement these strategies an integrated platform technology consisting of (photo)electrochemical, spectroscopic, microscopic and surface tension measurement techniques will - be developed. This multi-disciplinary approach will allow precise monitoring of morphological changes in photoactive films that enhance activity in terms of optimal kinetics of photoinduced charge transfer. An unprecedented level of electrochemical - control over photosensitiser assembly at soft interfaces will be attained, generating photoactive films with unique photophysical properties. Fundamental insights gained may potentially facilitate the emergence of new class of solar conversion - devices non-reliant on solid state architectures. - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Ireland - - - SOFT-PHOTOCONVERSION - - - ERC-2016-STG - - - 716792 - - - - - EIDGENOESSISCHE ANSTALT FUER WASSERVERSORGUNG ABWASSERREINIGUNG UND GEWAESSERSCHUTZ - - - EUR 175 419,60 - - - Spatial and temporal biotransformation of micropollutants in a lake ecosystem - - - EUR 175 419,60 - - - Switzerland - - - Research Organisations - - Freshwaters are increasingly contaminated with a variety of pesticides, pharmaceuticals, personal care product ingredients and industrial chemicals referred as “micropollutants” (MPs). Most of these MPs are poorly retained by - wastewater treatment plants, and thus are released into natural water bodies, where they can travel all the way to the raw water of drinking water treatment plants. Very little information is currently available on the persistence and transformation - of MPs in lake ecosystems. This project aims to investigate the fate of twelve MPs in lake Greifensee in Switzerland by measuring their transformation rates at different depths and seasons. To this end, lake water will be sampled at different depths - in Lake Greifensee, and natural microbial communities (bacteria and phytoplankton) will be exposed to a mixture of different MPs using semipermeable plastic bags that will be redeployed to their original depth. The bags will let gases, salts and ions - be exchanged with the outside environment, but will retain MPs and microorganisms inside the bag. At regular intervals, MP concentrations and their transformation products in the bags will be determined in order to calculate biotransformation rates - of MPs at different depths of the lake. Phytoplankton and bacteria communities will be analyzed to assess the role of microorganisms in MP transformation using cutting edge “omics” methods such as metagenomics. This project will be unique in that it - actually quantitatively describes the extent of MP biotransformation in situ, and thus eliminates many of the uncertainties involved in estimating in-field biodegradation based on laboratory experiments. It will also bring more in-depth knowledge on - the drivers of biotransformation, whether they are of bacteria or phytoplankton origin. This project will hence foster improved risk assessment and management of the release of contaminants into the environment. - - 2019-09-04, ongoing project - - - 2017-09-05 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - LakeMP - - - H2020-MSCA-IF-2016 - - - 750700 - - - - - UNIVERSITY COLLEGE LONDON - UNIVERSITY COLLEGE LONDON - - - EUR 1 500 000 - - - Peri-Ocularly Navigated Exteroceptive Snake Robot for Novel Retinal Interventions - - - EUR 1 500 000 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Intraocular treatments require manipulation of structures with dimensions comparable to hand tremor. The demanded dexterity, coupled with reduced haptic and depth perception, calls for robotic assistance. - - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - PIONEER - - - ERC-2016-STG - - - 714562 - - - - - CRANFIELD UNIVERSITY - CRANFIELD UNIVERSITY - - - EUR 1 499 655,89 - - - Sustainable Chemical Alternatives for Re-use in the Circular Economy - - - EUR 1 499 655,89 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This proposal seeks to develop a novel non-invasive, real-time direct observation methodology to provide new knowledge on the mechanisms underpinning crystal growth and harvesting within membrane crystallisation reactor - technology. Crystallisation represents one of the most important separation processes in the chemical industry and will play a critical role in the circular economy through enabling the recovery of resources from wastewater to yield an array of - sustainable low cost chemicals for use in European industries. Existing crystallisation reactor designs suffer from imperfect mixing and inhomogeneous solvent removal which makes control of crystal quality and consistency problematic and can limit - application of the final product. - - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - SCARCE - - - ERC-2016-STG - - - 714080 - - - - - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - - - EUR 175 419,60 - - - Affordable DNA Mapping using Solidstate-Nanopores - - - EUR 175 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - DNA analysis will become an important clinical tool in identification the composition of microbial species living in the gut. The most dominant technique at the time is based on PCR amplification of the 16s rDNA gene and - subsequent sequencing of the variable region in the gene. This method however is limited in the amount of detail it provides and is notoriously susceptible to primer bias. Furthermore, due to the requirement of a PCR machine and sequencer the - technique is too expensive and time consuming for a clinical setting. - - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - DNA NANO MAP - - - H2020-MSCA-IF-2016 - - - 751121 - - - - - THE HEBREW UNIVERSITY OF JERUSALEM - THE HEBREW UNIVERSITY OF JERUSALEM - - - EUR 1 867 181 - - - A regional history of medicine in the modern Middle East, 1830-1960 - - - EUR 1 867 181 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The purpose of this project is to write a long-term regional history of medicine in the Middle East and North Africa from a transnational and multi-layered perspective. A regional approach will enable tracing both global - influences and local specificities, while a long-term perspective (1830-1960) will allow tracing continuity and change from the late Ottoman Middle East through the colonial to the post-colonial periods. Combining archival and published sources in - Arabic, French, English, Hebrew, English, German and Ottoman Turkish, it will offer a unique perspective into the formation of the modern Middle East. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Israel - - - Mideast Med - - - ERC-2016-COG - - - 723718 - - - - - UNIVERSITY OF LEEDS - - - EUR 183 454,80 - - - Scaffold hybridization approach targeting PPIs - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Protein-protein interactions (PPIs) control all cellular processes relevant to health and disease, hence an outstanding challenge in chemical biology is to develop generic approaches for PPI inhibition. Such inhibitors (or - chemical probes) represent unique tools to understand biological processes and starting points for drug discovery, for treatment of multiple illnesses for which effective treatments don’t currently exist e.g. cancer. - - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SHAPPI - - - H2020-MSCA-IF-2016 - - - 749012 - - - - - UNIVERSITEIT UTRECHT - - - EUR 177 598,80 - - - Exploiting in vitro evolution of macrocyclic glycopeptides to explore selectin interactions - - - EUR 177 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Many important biological processes involve binding of proteins to carbohydrates, including the recruitment of immune cells to tissues by proteins called selectins. The core binding requirement of all three types of selectins - is a four sugar unit called the Sialyl LewisX epitope. However, affinity for this epitope alone is low. Further requirements for binding of selectins to their glycoprotein ligands include other carbohydrate and protein moieties, as well as sulfation - of the carbohydrate or tyrosines. Open questions include what is necessary and sufficient for tight binding to each selectin, what sorts of ligands can bind to all selectins, and how the binding requirements can be presented on a synthetic scaffold. - Answers to these questions will lead to a better understanding of the selectins, tools for future biological studies, and hopefully new medications for the many immune disease processes in which their abnormal functioning has been implicated. - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - GlycoPeptides - - - H2020-MSCA-IF-2016 - - - 746631 - - - - - UNIVERSITY OF SURREY - - - EUR 183 454,80 - - - Ageing Diversity: LGBT* – Housing and Long-term Care - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Existing studies about Lesbian, Gay, Bisexual, and Trans* (LGBT*) people have shown that those aged over fifty years of age (hereafter LGBT* seniors), are more likely to be childless, single and to live alone than their - heterosexual peers. Housing, either with or without care, is a principal area of concern to LGBT* seniors, yet few studies exist in Europe that have directly addressed this topic. AgedLGBT* will make a significant contribution to knowledge about - LGBT* seniors and housing by comparing and synthesizing the work of research projects conducted in Germany and the UK. It therefore represents a unique and valuable opportunity to understand this issue on a broader, international scale and - significantly adds to the value and usefulness of European social science about LGBT* ageing. AgedLGBT* will use the data of two nationally unique research projects of the Alice Salomon University of Applied Sciences Berlin (D) and one conducted by - the University of Surrey (UK) integrating these and adding to them across four interrelated work packages (WP): AgedLGBT* will compare and synthesize data from the research projects GLESA & GLEPA (D) and SAFE Housing (UK) to investigate - similarities and variations about LGBT* seniors and housing (WP I). WP II comprises interviews with key experts, dealing with excluded minorities (such as LGBT* elders with lower income as well as trans* and intersexual seniors). A secondment at - Stonewall Housing, UK, will support the realization of the interviews and strengthen the social work experience of the researcher. A social simulation model (WP III) for the cohorts of future LGBT* elders based on the analysis of data in WP I will - provide new ways to hypothesize and understand the issue. Also the training in Agent-Based Modelling will be crucial for the researcher’s prospects. A symposium with experts (WP IV) and practitioners will be organised as a feedback platform with - practical relevance and for looking beyond a LGBT* perspective. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - AgedLGBT - - - H2020-MSCA-IF-2016 - - - 749760 - - - - - HOGSKOLEN I BODO - - - EUR 231 642,20 - - - Metabolism of Novel Strains of Arctic Algae - - - EUR 231 642,20 - - - Norway - - - Higher or Secondary Education Establishments - - Due to increasing environmental and economic pressures, there is a need to develop more efficient and sustainable food, feed and fuel production systems. Microalgae have substantial potential as single-cell molecular factories - for producing high quality lipids, proteins and carbohydrates. They are capable of faster growth rates than crop plants and synthesize valuable metabolites that do not occur naturally in other primary producers. However, a major bottleneck that - currently limits widespread microalgae production are the low yields achieved by commercial strains in cold climates. This project will develop new varieties of microalgae isolated from Arctic and Antarctic environments for applied bioprocesses. The - work will include studying the metabolism of novel microalgae in low temperature bioreactors using functional genomics. The researcher will spend the outgoing phase at an established microalgae metabolism laboratory in the USA, where complete and - very high quality training will be given in cutting-edge Next Generation Sequencing (NGS) technology. Genomic and transcriptomic work will be paired with metabolomics to give new insights into the regulation of metabolism in non-model microalgae - species. The research will also include integrating data together into metabolic flux model frameworks. The major research outcomes will be (1) Genome-scale characterization of brand-new varieties of microalgae (2) Development of novel microalgae - bioprocesses for high yields of lipids, proteins and carbohydrates in cold climates (3) Predictive metabolic models for maximizing yields of products of interest in non-model varieties of microalgae. In addition, comprehensive work and dissemination - plans are presented that will target scientists, industry and the public. - - 2020-04-30, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Norway - - - MONSTAA - - - H2020-MSCA-IF-2016 - - - 749910 - - - - - UNIVERSIDAD DE OVIEDO - - - EUR 158 121,60 - - - Vancomycin resistance regulation in the antibiotic-producers streptomycetes - - - EUR 158 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - Antimicrobial resistance is a critical health issue today. Important pathogens have become resistant to many or all available antibiotics and limited new antibiotics are in the pipeline. Vancomycin is used as a ‘last resort’ - antibiotic treatment for many bacterial infections, but worryingly vancomycin resistance (VR) has spread to major hospital-acquired pathogens such as Enterococcus faecium and Staphylococcus aureus. Most pathogen VR gene clusters likely came from - actinomycetes, the natural producers of glycopeptides and most other antibiotics of natural origin. Induction of VR in the model actinomycete Streptomyces coelicolor is highly influenced by nutritional conditions, in particular by the phosphate (Pi) - concentration in the medium. My previous work has shown that VR in S. coelicolor is blocked with Pi concentrations above 0.2%; suggesting a key role of this nutrient in VR repression. Furthermore, I have isolated a mutant strain (SCO2594::aac(3)IV) - lacking this Pi control over VR. This mutant has cell wall synthesis defects and up-regulates a putative small non-coding RNA (sRNA) located in the promoter region of the vanSR regulatory genes. This project aims to understand the mechanisms of Pi - regulation of the S. coelicolor van cluster, and to expand this study to other nutrients that may also control VR. A main focus is on the role of sRNAs in the regulation, as they offer potential novel targets for future clinical exploitation such as - “antisense RNA therapy”. The work also aims to understand the role of SCO2594 in VR and to identify new players involved in the process. The proposed project represents an excellent opportunity for the researcher to develop new skills whilst helping - to ramp up the development of new antimicrobial platforms in the Salas lab. - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - Vanrestrep - - - H2020-MSCA-IF-2016 - - - 740080 - - - - - STOCKHOLMS UNIVERSITET - STOCKHOLMS UNIVERSITET - - - EUR 1 487 245 - - - Automatized Catalysis and Single-Carbon Insertion - - - EUR 1 487 245 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project is aimed at accelerating the synthesis of important organic molecules through key enabling technologies towards automatized catalysis and single-carbon insertion reactions. Transferring the simplest carbon units - to organic molecules has the potential to change the way we approach synthesis planning through new asymmetric skeletal homologations and rearrangements of simple raw materials, for which only long workarounds exist now. These methods can reduce to - half the manipulations required to access relevant medicines, organocatalysts, ligands, bio-molecular tools and photovoltaic devices. They target unreactive functions to introduce fundamental one-carbon units (CO or C) that are present in virtually - any organic compound. New powerful reagents that resemble these basic single-carbon units in excited electronic configurations are to be developed for this purpose. The new catalytic methods needed are based on the solid grounds of carbene-transfer - reactions and the recent advances of my group in the development of new homogeneous catalysts. Moreover, a new catalyst platform will be developed to complement our existing portfolio for success in the challenging processes targeted in this - proposal. We aim to pioneer a fully automatized workflow for research in catalysis that devoid the synthesis of organic ligands replacing them by combinatorial assemblies built in situ from un-structured simple molecules. The new reactions arising - from these new catalysts and reagents will expedite the valorization of raw materials (such as carbonyls, olefins and hydrocarbons) into important chiral molecules in a single transformation. This bold aim is a priority of the European Commission for - the coming years as it will save time, protect the environment and reduce cost at once. Thus, these innovative technologies have the potential of transforming the research workflow in homogeneous catalysis and the logics of retrosynthesis of organic - molecules at a fundamental level. - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Sweden - - - single-C - - - ERC-2016-STG - - - 714737 - - - - - UNIVERSIDAD POMPEU FABRA - UNIVERSIDAD POMPEU FABRA - - - EUR 1 499 805 - - - A distributional MOdel of Reference to Entities - - - EUR 1 499 805 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - "When I asked my seven-year-old daughter "Who is the boy in your class who was also new in school last year, like you?", she instantly replied "Daniel", using the descriptive content in my utterance to identify an entity in - the real world and refer to it. The ability to use language to refer to reality is crucial for humans, and yet it is very difficult to model. AMORE breaks new ground in Computational Linguistics, Linguistics, and Artificial Intelligence by developing - a model of linguistic reference to entities implemented as a computational system that can learn its own representations from data. - - 2022-01-31, ongoing project - - - 2017-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Spain - - - AMORE - - - ERC-2016-STG - - - 715154 - - - - - BEN-GURION UNIVERSITY OF THE NEGEV - BEN-GURION UNIVERSITY OF THE NEGEV - - - EUR 150 000 - - - Hierarchical Inorganic Nanomaterials as Next Generation Catalysts and Filters - - - EUR 150 000 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In the coming few decades, two major global grand challenges will continue to attract the attention of scientists and engineers in academia and industry: achieving clean water and clean energy. This PoC establishes the - development of two prototypes, water oxidation catalyst and water purification filter, by creating inexpensive, abundant and versatile hierarchical structures of inorganic nanomaterials (HSINs). - - - 2018-08-31, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Israel - - - 3Dmaterials4Energy - - - ERC-2016-PoC - - - 755301 - - - - - STOCKHOLMS UNIVERSITET - STOCKHOLMS UNIVERSITET - - - EUR 1 968 375 - - - High-valent protein-coordinated catalytic metal sites: Geometric and Electronic ARchitecture - - - EUR 1 968 375 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - It is estimated that almost half of all enzymes utilize metal cofactors for their function, for example the respiratory complexes and the oxygen-evolving photosystem II, the most fundamental requirements for aerobic life as we - know it. If we could mimic nature’s use of metals for harvesting sunlight, energy conversion and chemical synthesis it would eliminate the need for fossil fuels and greatly increase the possibilities of chemical industry while reducing the - environmental impact. Achieving this type of chemistry is an outstanding testament to evolution and understanding it is a glaring challenge to mankind. - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Sweden - - - HIGH-GEAR - - - ERC-2016-COG - - - 724394 - - - - - UNIVERSITA DI PISA - KUNGLIGA TEKNISKA HOEGSKOLAN - UNIVERSIDAD POLITECNICA DE MADRID - UGANDA INDUSTRIAL RESEARCH INSTITUTE - KENYATTA UNIVERSITY - TARTU ULIKOOL - AGILEWORKS OU - - - EUR 992 250 - - - Euro-African Open Biomedical Engineering e-Platform for Innovation through Education - - - EUR 992 250 - - - Italy - Sweden - Spain - Uganda - Kenya - Estonia - Estonia - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The project aims at creating an EU-Africa e-Infrastructure, UBORA, for open source co-design of new solutions to face the current and future healthcare challenges of both continents, by exploiting networking, knowledge on - rapid prototyping of new ideas and sharing of safety criteria and performance data. The e-infrastructure will foster advances in education and the development of innovative solutions in Biomedical Engineering (BME), both of which are flywheels for - European and African economies. It is conceived as a virtual platform for generating, exchanging, improving and implementing creative ideas in BME underpinned by a solid safety assessment framework. Besides the provision of resources with designs, - blueprints and support on safety assessment and harmonisation, specific sections for needs identification, project management, repositories and fund raising are also foreseen. - - - 2019-06-30, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.4.3.1., H2020-EU.1.4.1.3., H2020-EU.1.4.3.2."> - - - INFRASUPP-03-2016 - Support to policies and international cooperation for e-infrastructures - - - CSA - Coordination and support action - - - Italy - - - UBORA - - - H2020-INFRASUPP-2016-1 - - - 731053 - - - - - UNIVERSIDAD POMPEU FABRA - UNIVERSIDAD POMPEU FABRA - - - EUR 150 000 - - - A Mnemonic system based on stimulation-free Neuroimaging - - - EUR 150 000 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project’s aim is the commercialization of a neurotechnology device, MNeuronic, that helps its users to improve their memory retention. MNeuronic can be used in cognitive rehabilitation on patients with mild to moderate - decline in memory function as well as by healthy users, as a cognitive training method at home. The system will be mounted on wearable, relatively affordable hardware. Its core technology is grounded on principles and ideas developed in my current - ERC-StG project on attention and perception. In particular, MNeuronic capitalizes on the natural fluctuations of neural excitability in the human brain using real-time phase prediction. This confers two important commercial strengths. One is - efficiency, because MNeuronic anticipates upcoming optimal brain states before they occur, rather than reacting to past states. Second, MNeuronic affords unprecedented levels of temporal precision. Besides its direct application for memory - enhancement, the core principles that ground MNeuronic are transferable to further applications in neurotechnology for learning/education, cognitive training, recreation (neurogaming) or, wellness. This opens a second commercialization route that - reaches out to other neurotechnology companies, which will also be exploited in this project. The software implementing MNeuronic (real-time analysis filters and prediction algorithms) will be protected under a dual license that will allow us to - combine a proprietary license offered to client companies, and open-licenses addressed to non-profit research and education organizations. Because MNeuronic offers non-invasive, stimulation-free solutions, it will appeal as a less aggressive - rehabilitation support tool to be marketed in clinical contexts. In addition, with an effort toward affordable costs and wearable hardware, we intend to cater non-clinical, home-users. Home-use neurotechnology is becoming an increasingly important - emerging market because its potential size and growth rate. - - 2018-06-30, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Spain - - - MNeuronic - - - ERC-2016-PoC - - - 727595 - - - - - UNIVERSITAT POLITECNICA DE CATALUNYA - UNIVERSITAT POLITECNICA DE CATALUNYA - - - EUR 1 499 887 - - - Atmospheric Pressure plAsma meets biomaterials for bone Cancer HEaling - - - EUR 1 499 887 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Cold atmospheric pressure plasmas (APP) have been reported to selectively kill cancer cells without damaging the surrounding tissues. Studies have been conducted on a variety of cancer types but to the best of our knowledge - not on any kind of bone cancer. Treatment options for bone cancer include surgery, chemotherapy, etc. and may involve the use of bone grafting biomaterials to replace the surgically removed bone. - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Spain - - - APACHE - - - ERC-2016-STG - - - 714793 - - - - - TECHNISCHE UNIVERSITAET GRAZ - TECHNISCHE UNIVERSITAET GRAZ - JOANNEUM RESEARCH FORSCHUNGSGESELLSCHAFT MBH - - - EUR 1 499 108,76 - - - Smart Core/shell nanorod arrays for artificial skin - - - EUR 1 499 108,76 - - - Austria - Austria - Austria - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - The replication of the circle of information coming from the environment, to the skin, to an action mediated by the brain, requires a lot of advances in smart technology and materials development. Embedding sensors in smart - architectures that record the stimulus from the environment and transform it into action is the objective of artificial skins. At the moment, different sensors have to be implemented in the artificial skin matrix for each stimulus. - - - 2021-11-30, ongoing project - - - 2016-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Austria - - - SmartCore - - - ERC-2016-STG - - - 715403 - - - - - INSTITUT VON KARMAN DE DYNAMIQUE DES FLUIDES - KUNGLIGA TEKNISKA HOEGSKOLAN - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - INSTYTUT MASZYN PRZEPLYWOWYCH IM ROBERTA SZEWALSKIEGO POLSKIEJ AKADEMII NAUK - IMP PAN - TECHNISCHE UNIVERSITEIT DELFT - UNIVERSITY OF SOUTHAMPTON - KATHOLIEKE UNIVERSITEIT LEUVEN - ECOLE CENTRALE DE LYON - NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA - SIEMENS INDUSTRY SOFTWARE NV - SIEMENS GAMESA RENEWABLE ENERGY AS - CENTRE TECHNIQUE DES INDUSTRIES AERAULIQUES ET THERMIQUES - - - EUR 3 844 758,48 - - - Smart mitigation of flow-induced acoustic radiation and transmission for reduced aircraft, surface transport, workplaces and wind energy noise - - - EUR 3 844 758,48 - - - Belgium - Sweden - France - Switzerland - Poland - Netherlands - United Kingdom - Belgium - France - Greece - Belgium - Denmark - France - - - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - A step change in our noise mitigation strategies is required in order to meet the environmental targets set for a number of sectors of activity affecting people through noise exposure. Besides being a hindrance to our daily - life and subject to regulations, noise emission is also a competitive issue in today’s global market. To address these issues, new technologies have been emerging recently, based on radically new concepts for flow and acoustic control, such as - micro-electro-mechanical devices (MEMs), meta-materials, porous treatment of airframe surfaces, airfoil leading-edge or trailing-edge serrations, micro-jets, plasma actuation, … Some of these new ideas appear nowadays promising, but it now appears to - this consortium that the development and maturation of novel noise reduction technologies is hindered by three main factors. The first factor is an insufficient understanding of the physical mechanisms responsible for the alteration of the flow or - acoustic fields. In absence of a phenomenological understanding, modelling and optimization can hardly be successful. Secondly, tight constraints (safety, robustness, weight, maintainability, etc.) are imposed to any novel noise mitigation strategy - trying to make its way to the full-scale industrial application. Thirdly, there is an insufficient knowledge about the possibilities that are nowadays offered by new materials and new manufacturing processes. With this project, we intend to setup a - research and training platform, focused on innovative flow and noise control approaches, addressing the above shortcomings. It has the following objectives: i) fostering a training-through-research network of young researchers, who will investigate - promising emerging technologies and will be trained with the inter-disciplinary skills required in an innovation process, and ii) bringing in a coordinated research environment industrial stakeholders from the aeronautical, automotive, wind turbine - and cooling/ventilation sectors. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Belgium - - - SmartAnswer - - - H2020-MSCA-ITN-2016 - - - 722401 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 183 454,80 - - - Early Upper Palaeolithic personal ornaments and behavioural adaptations - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - EU-BEADS investigates symbolically mediated behaviour of Early Upper Palaeolithic modern humans through the study of personal ornaments. Specifically, EU-BEADS will focus on the Levantine region between 60,000 and 40,000 years - ago. The goal is a better understanding of variation and standardisation in shell bead production and use, as well as establishing new criteria for identification of anthropic modifications of marine shell beads. To achieve this, EU-BEADS employs a - range of state-of-the-art zooarchaeological and taphonomic methodologies in conjunction with newly learned analytical techniques namely finite element analysis, use-wear analysis and GIS. In addition, EU-BEADS aims to develop a new analytical method - to improve quantification of human actions in the production of shell beadwork using geometrics morphometrics. The large shell bead collection of Ksar’ Akil (Lebanon) will serve as a case study. The high quality, multidisciplinary research results - will contribute significantly to our knowledge of Early Upper Palaeolithic behavioural adaptations and of modern human symbolically mediated behaviours in general. - - 2018-09-27, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - EU-BEADS - - - H2020-MSCA-IF-2014 - - - 656325 - - - - - THE UNIVERSITY OF SHEFFIELD - STOCKHOLMS UNIVERSITET - UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA - - - EUR 1 569 640,32 - - - Catalytic Methods for Sustainable Synthesis. A Merged Experimental and Computational Approach - - - EUR 1 569 640,32 - - - United Kingdom - Sweden - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - CATMEC is a multi-partner European Joint Doctorate (EJD) Programme offering research training in state-of-the-art sustainable chemical synthesis, catalysis, computational chemistry and bioactive molecule design on both - traditional and non-traditional (eg flow) platforms. This Doctoral Training Programme integrates complementary, interdisciplinary and intersectoral training and together with enhanced European mobility through planned secondments of researchers, will - contribute to EU policy objectives in scientific training and degree assessment. The researchers will be supervised and mentored by internationally recognised experts and have access to state-of-the-art equipment. Hands-on training will be - supplemented by formal training courses in relevant and related fields, and a wide variety of complementary training courses, workshops and seminars. The training of researchers will benefit from secondments to industrial partners, gaining exposure - to commercial and complementary environments. Overall, it is anticipated that the CATMEC project will provide Early Stage Researchers (ESRs) with an outstanding training experience, through extensive technical and complementary skills development. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-EJD - European Joint Doctorates - - - United Kingdom - - - CATMEC - - - H2020-MSCA-ITN-2016 - - - 721223 - - - - - CONSIGLIO NAZIONALE DELLE RICERCHE - IONFLY VACUUM AND PLASMA TECHNOLOGY SRL - - - EUR 100 000 - - - Dielectric MicroSpacer Technology - - - EUR 100 000 - - - Italy - Italy - - - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Several technological applications need tools for keeping a stable micrometric distance between two surfaces. The requirements are more stringent if electrical insulation has to be guaranteed between the surfaces and even more - if also thermal insulation has to be satisfied. - - 2018-09-30, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-04-2016-2017 - FET Innovation Launchpad - - - CSA - Coordination and support action - - - Italy - - - DMS - - - H2020-FETOPEN-4-2016-2017 - - - 754568 - - - - - KATHOLIEKE UNIVERSITEIT LEUVEN - - - EUR 160 800 - - - Accelerating Clinical Translation. Charting the Politics of Translation in the European Union - - - EUR 160 800 - - - Belgium - - - Higher or Secondary Education Establishments - - In the post–genomic era, innovation policies in biomedicine are increasingly being driven by the notion that constant advancements in biological knowledge fail to materialize into tangible therapeutic outcomes. Discursively - framed in terms of a “gap” between “bench” and “bedside” in need of urgent “bridging”, this representation of the shortcomings of biomedical innovation has propelled growing efforts tailored towards the clinical translation of research results. In - the European Union, the acceleration of clinical translation has been positioned as a cornerstone of its innovation strategy, as attested by the launch of a host of translational policy initiatives and a vast array of regulatory reforms in the - process of medicines approval. - - 2020-01-21, ongoing project - - - 2018-01-22 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Belgium - - - ACTrans - - - H2020-MSCA-IF-2016 - - - 753531 - - - - - THE UNIVERSITY OF EDINBURGH - - - EUR 195 454,80 - - - Masculinities, Youth and Violence in the Moroccan Underclass: Young Men and Their Future Selves. - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Male juvenile delinquency as represented by self-styled tcharmils has been the focus of a moral panic in Morocco over the last years. The tcharmil subculture has gained visibility through a social-media propagated aesthetic - that turns the stigma of social disqualification into a source of pride by extolling assertive masculinity, violence, and the transgression of social and religious norms. By adopting consumerist values that overlap with those of more privileged - classes, and by frequenting the latter’s urban spaces of leisure, the tcharmil blur social boundaries. The resulting anxieties among the privileged has resulted in public campaigns and police crackdown. MoroccoMasculinities examines the construction - of the masculinities of disadvantaged young men in order to understand how gender, class, space and ethnicity intersect in juvenile moral and cultural formations in today’s Morocco. On the one hand, studying the tcharmil subculture reveals how - juvenile subjectivities are reshaped by the combined effect of urbanisation, the new media, and state policies interlinked with global systems of regulation such as neo-liberal reforms, restrictions on migratory movements, and the intensification of - the struggle against the hashish economy. On the other hand, the study of state reactions to the same subculture allows to highlight changing patterns of criminalisation: the unprecedented emphasis on male delinquency possibly reflects a strategy of - discursive de-politicisation of the threats to an established order faced with the challenges of the Arab Spring and its aftermaths. - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - United Kingdom - - - MoroccoMasculinities - - - H2020-MSCA-IF-2016 - - - 753562 - - - - - THE UNIVERSITY OF EDINBURGH - - - EUR 195 454,80 - - - Development of the new internally-heated diamond-anvil cell for planetary mineral physics: Application to high-pressure melting of H2O ice - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - For the past few decades, diamond anvil cell (DAC) has been the most commonly used static high-pressure device to reproduce simultaneous high pressure (P) and temperature (T) conditions of deep planetary interiors. - Laser-heated DAC achieved P-T conditions corresponding to the centre of the Earth. However, the laser heating system causes large temperature uncertainties (±10%), which is critical when one tries to understand planetary interiors based on phase - relations of the candidate materials. The major objective of this proposal is therefore, to develop a new heating system for the DAC which enables us to heat the sample stably and homogeneously. The new design will be based on so-called - internally-heated DAC (IHDAC). In an existing IHDAC, a thin metallic heater which is the sample at the same time, provides homogeneous high temperature. One of the limitations of the existing system is that it is applicable only to the metallic - sample. Therefore, (1) we aim to develop a micro-heater configuration which can heat any type of materials, e.g., silicate, oxide, and H2O. We plan to achieve the P-T condition of P = 200 GPa and T = 4000 K. Then (2) we will conduct high-pressure - melting experiments on H2O ice. The melting temperature of H2O ice under pressure places important constraints on the structure of Ice Giants such as Uranus and Neptune. Previously reported melting temperatures of H2O show large discrepancies, one of - the major reasons for which is that most of those studies were based on the laser heating with large temperature uncertainties. Our new IHDAC will offer incontrovertible melting data from homogeneous and stable heating, and therefore it has a great - potential to solve the long-standing controversy of the existing melting temperatures. Our new IHDAC will be a conventional technique for the researches on the planetary interior for the next decade. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - United Kingdom - - - NEWDIA4Planet - - - H2020-MSCA-IF-2016 - - - 753858 - - - - - KOBENHAVNS UNIVERSITET - HELMHOLTZ-ZENTRUM FUER UMWELTFORSCHUNG GMBH - UFZ - Masarykova univerzita - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - EIDGENOESSISCHES DEPARTEMENT FUER WIRTSCHAFT, BILDUNG UND FORSCHUNG - PROFESSIONSHOJSKOLEN METROPOL - EIDGENOESSISCHE ANSTALT FUER WASSERVERSORGUNG ABWASSERREINIGUNG UND GEWAESSERSCHUTZ - HOFOR AS - FERA SCIENCE LIMITED - STOCKHOLMS UNIVERSITET - - - EUR 3 976 833,96 - - - Natural Toxins and Drinking Water Quality - From Source to Tap - - - EUR 3 976 833,96 - - - Denmark - Germany - Czech Republic - Spain - Switzerland - Denmark - Switzerland - Denmark - United Kingdom - Sweden - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - Clean drinking water is crucial to human health and wellbeing. The ambition of the NaToxAq ETN network is to expand the research basis for EU’s leading role in securing high quality drinking waters for its citizens. Focus is - on natural toxins – a large group of emerging contaminants with unknown impact on drinking water resources. Both known toxins, like cyanotoxins, cyanogenic glucosides and terpenes and not yet explored toxins will be investigated. Twenty leading - universities, research institutions, and water enterprises will pioneer the field through joint training of 15 ESRs investigating natural toxin emission via water reservoirs to water works and consumers. The natural toxin challenge is addressed by - the concerted work of the ESRs within 4 scientific work packages comprising origin, distribution, fate and remediation. Priority toxins are selected using in silico approaches accompanied by novel non-targeted and targeted analyses to map natural - toxins along vegetation and climatic gradients in Europe. Invasion of alien species, toxin emission, leaching and dissipation will be under strong influence of climate change. Data collected for toxin emission, properties and fate will be used to - model effects of climate, land use, and design of remediation actions. Special attention will be paid to toxin removal at water works including development of new technologies tailored to remove natural toxins. The results will contribute to - strengthening of European policies and regulation of drinking water, while new business opportunities within the fields of water supply and treatment, chemical monitoring and sensing, and the consulting sector will arise from academia-indstry - collaborations. The urgency of the challenge, its eminent knowledge gaps, its multifaceted and multidisciplinary nature, and the need for scientific and public awareness to be communicated by ESRs in a balanced way makes the topic ideal for a - European mobility and training network. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Denmark - - - NaToxAq - - - H2020-MSCA-ITN-2016 - - - 722493 - - - - - UNIVERSITE CATHOLIQUE DE LOUVAIN - - - EUR 172 800 - - - MadbaM: automated tools for precision calculations of the Baryon Asymmetry of the Universe in BSM models - - - EUR 172 800 - - - Belgium - - - Higher or Secondary Education Establishments - - The measured Baryon Asymmetry of the Universe (BAU) is a firm evidence for the existence of new physics beyond the Standard Model of particle physics (BSM). Despite of that, the offer of scientific software for the high-energy - physics community currently misses dedicated tools devoted to precise baryogenesis computations in BSM models. The aim of the present proposal is to fill this gap, providing the necessary tools in order to bring the theoretical computation of the BAU - into a precision era, and employing them to use the BAU as a powerful observable for the characterisation and test of physics BSM. The main deliverable will be a scientific software, MadbaM, able to precisely compute the BAU in as many BSM scenarios - as possible. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Belgium - - - MadbaM - - - H2020-MSCA-IF-2016 - - - 750627 - - - - - UNIVERSITE CATHOLIQUE DE LOUVAIN - - - EUR 172 800 - - - House Poetics. An 'assemblage' approach to the production and transmission of value in Bronze Age Crete. - - - EUR 172 800 - - - Belgium - - - Higher or Secondary Education Establishments - - The Project explores the fundamental social question of the creation of value, by investigating House Societies in Bronze Age Crete (3100-1200 BC). Houses are understood as intergenerational, locus-bound social groups, holding - an estate of material and symbolic wealth, transmitted along a real or imaginary line, legitimized by kinship or affinity, or both. Because of their distinct focus on the creation and transmission of value, Houses are an ideal framework for answering - this research question, but their longevity makes it difficult to explain change. By fusing Houses with the philosophical and sociological premises of Assemblage theory, which argues that social entities are not fixed but constituted by relationships - between humans, non-humans and materials that can territorialize and deterritorialize value, the project creates a new social ontology which perceives Houses in a constant state of becoming, continuously affecting and being affected by the changing - social world they inhabit. The methodological advantage of this interdisciplinary model, combining philosophical, sociological, archaeological and scientific perspectives, will be demonstrated empirically through the integrated use of GIS spatial - analysis and material culture analysis, in a series of case studies (selected on the basis of availability of good contextual information for primary data and a large corpus of published evidence) targeting three strategic scales of House formation - and interaction: a single site (Petras), its regional context (East Crete) and their broader geopolitical networks (the Aegean and the East Mediterranean). Using GIS to explore Houses as Assemblages will offer an original integration of spatial, - material and social scales, which can revitalize our understanding of past societies and transform the study of social relations in general. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Belgium - - - HousePoetics - - - H2020-MSCA-IF-2016 - - - 752179 - - - - - UNIVERSITY OF SOUTHAMPTON - - - EUR 183 454,80 - - - Resilient steel frame against fire and seismic hazards - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Conventional seismic-resistant structures are designed to experience significant damage under moderate-to strong earthquakes and this results in socio-economic losses such as injuries, high repair costs and disruption of the - building use or occupation. To address this issue, researchers have developed modern seismic-resilient frames that can avoid inelastic deformations (i.e. damage) in structural members. Fire is another type of loading, which can cause significant - damage and collapse. Moreover, fire after strong earthquakes is also a highly probable catastrophic event as it has been seen after recent earthquakes (e.g. Indonesia 2009, Chile 2010). Despite the fact that the risk of fires is high after strong - earthquakes, seismic resilient structural systems have not yet been studied against fire and fire after earthquake loading. This project will assess the behaviour of modern seismic-resilient self-centering post-tensioned steel frames against fire - loading and will propose modifications of their structural details so that, apart from seismic resilience, fire robustness can be also achieved. The project aims to develop, for the first time, an innovative steel frame characterized by the unique - combination of minimal damage seismic behaviour and robustness against fire and post-earthquake fire loading. - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ResFrameFireSeismic - - - H2020-MSCA-IF-2016 - - - 751904 - - - - - UNIVERSITY OF SOUTHAMPTON - - - EUR 195 454,80 - - - Time-dependent design and assessment of prestressed steel-concrete composite bridges with external FRP tendons - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Large EU projects and surveys reveal that the frequency and cost of bridge repairs in Europe have significantly increased due to traffic loads higher than those considered in the initial design, harsh environmental conditions, - use of de-icing salts especially in countries with cold climates, poor quality of construction materials, and limited maintenance. Most importantly, the aforementioned projects and surveys highlight that current repair and strengthening methods are - costly and time-consuming and result in large socio-economic losses due to disruption of traffic flow such as travel delays, longer travel distances, insufficient move of goods, and loss of business. Therefore, bridge owners and bridge engineers - urgently seek to transfer into real-life projects more efficient and less disruptive methods for bridge repair, strengthening and maintenance. External post-tensioning is recognised as a powerful technique in the rehabilitation of existing bridges as - well as in the construction of new bridges. For the advantages of noncorrosive property and high strength, fibre reinforced polymer (FRP) composites are being increasingly used for external tendons instead of conventional steel ones. Existing - research on externally prestressed steel-concrete composite bridges has focused on the short-term loading. However, the inevitable loss of long-term performance of prestressed composite bridges is of primary concern in practice, especially when FRP - tendons are used. Therefore, it is necessary to investigate deeply the long-term behaviour of these bridges and, on this basis, to propose practical design guidelines. In this fellowship, an experimental and numerical study will be carried out to - understand the time-dependent performance of composite girder bridges with FRP tendons. Long-term tests will be performed. Moreover, a novel computer programme capable of performing time-dependent analysis will be developed and used to conduct an - extensive numerical investigation. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - TimePresCompBridge - - - H2020-MSCA-IF-2016 - - - 751921 - - - - - UNIVERSITE CATHOLIQUE DE LOUVAIN - - - EUR 172 800 - - - Innovative sol-gel strategies for the production of homogeneous, hydrothermally stable, andporous mixed metal oxide catalysts for biomass conversion applications - - - EUR 172 800 - - - Belgium - - - Higher or Secondary Education Establishments - - The project is focused on the preparation, characterization and application of (hydro)thermally stable, homogeneous, and porous metallosilicate catalysts. As a synthetic route we will apply non-hydrolytic sol-gel routes since - they produce materials with high homogeneity and they allow the one-step functionalization of the oxides surface. We will focus and demonstrate our results primarily on the synthesis of alumosilicates, and then broaden the work to Zr-, Ti-, Nb-, and - Ta-doped silicates. We will use advanced analytic techniques for the characterization of heterogeneous catalysts – infrared spectroscopy, solid state nuclear magnetic resonance, nitrogen and ammonia adsorption-desorption experiments, electron - microscopy, powder x-ray diffraction, small angle x-ray scattering, and surface analytical techniques – time-of-flight secondary ion mass spectrometry and x-ray photoelectron spectroscopy. We will evaluate our materials as catalysts in alcohol - dehydration. For this type of reaction it is desirable to have hydrothermally stable acidic material. Hydrothermal instability is usually the main drawback of mixed metal oxides. Therefore we will tune the hydrophobicity of prepared materials and - their surfaces by introduction of various organic groups in order to improve their performances. We will focus on the control of the pore size distribution as well and prepare stable and homogeneous materials with large pores applicable in catalytic - actions on bulky (bio)molecules. In such a way the project will establish fruitful cooperation between the two research groups – one focused primarily on the synthetic pathways to novel materials and the second focused on their application in - heterogeneous catalysis. The fellow will learn new characterization techniques and catalytic testing under industrially-relevant conditions. He will work independently, attain new soft skills and will prepare for the establishing of new research - group back in Brno. - - 2019-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Belgium - - - NewCat4Bio - - - H2020-MSCA-IF-2016 - - - 751774 - - - - - UNIVERSITY OF YORK - - - EUR 195 454,80 - - - Reading the genetic history of parchment manuscripts. - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Medieval texts are a window into the monastic world and an integral part of European written history. Most of our current understanding of the processes of codex construction comes from the careful examination of the clues to - manufacture on the object itself, the practice of codicology. Increasingly scholars are interested in the material qualities of the book. How and why were the decisions on the selection of materials made? Recent advances in analytical methods are - broadening the reach of codicology in unexpected ways and enabling these questions to be addressed. The SCRIBE project is at the forefront of this burgeoning field of molecular codicology, having developed and implemented an exciting new minimally - destructive DNA sampling technique, derived from routine parchment conservation practice. SCRIBE will further implement this method to generate two novel high throughput genomic datasets from parchment manuscripts. Firstly the materiality of the - manuscripts will be described by assessing the genetic relationship between the animals used to complete the codices. Secondly SCRIBE will be the first study to combine high throughput metagenomic techniques and novel bioinformatic approaches to a - large sample size of documents in multiple archives to look at the microbial fingerprints of parchments, to complement their provenance and curation. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SCRIBE - - - H2020-MSCA-IF-2016 - - - 747424 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 183 454,80 - - - Generation of new zebrafish models for the study of the pathogenesis of Huntington´s disease and for the identification of new therapeutic targets. - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Huntington´s disease (HD) is one of the nine neurodegenerative diseases (ND) caused by (CAG)n trinucleotide tract expansions that encode abnormally long polyglutamine (polyQ) tracts. The common features shared by many ND are - the misfolding and aggregation of toxic proteins. Thus, HD recapitulates features of other, more complicated ND. As HD is an autosomal dominant disorder, modeling this disease in vitro and in vivo is straightforward. Unfortunately, HD is, to date, - incurable and there are no drugs or therapies that are known to slow or prevent the disease. Thus, the strategies proposed in this project, taking advantage of the unique characteristics of the zebrafish as model organism to study human diseases, - will allow me to gain a deeper understanding of its pathogenesis, and to generate tools to accelerate the development of new therapies. Moreover, my findings may have relevance to other ND. First, I propose to generate new zebrafish transgenic lines - expressing different forms of human huntingtin (htt) (wild-type/mutant, full-length/exon1) fused to the photoconvertible fluorescent protein Dendra in whole body, neurons or glial cells using the UAS-GAL4 system. Next, I will validate the construct - integration in the fish genome and characterize the transgenic lines. After that, I will use these new generated models to study the life cycles of the previously mentioned forms of htt in vivo, and I will examine their clearance kinetics in vivo in - different tissues in the context of inhibition/stimulation of autophagy or ubiquitin-proteasome pathways. Moreover, I will assess the role played by the inflammasome in the context of the neuroinflammation present in HD. Finally, I will use these new - zebrafish lines to test novel therapeutic targets recently identified in the host lab, in order to develop new treatments for HD. - - 2020-04-30, Grant Agreement signed - - - 2018-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - HUNTINFISH - - - H2020-MSCA-IF-2016 - - - 746509 - - - - - WEIZMANN INSTITUTE OF SCIENCE - - - EUR 170 509,20 - - - Deciphering cell-cell and cell-microbiome interactions of innate lymphoid cells at the single cell level - - - EUR 170 509,20 - - - Israel - - - Higher or Secondary Education Establishments - - Battling acute and chronic enteric disease is a priority in Europe and worldwide, especially now at the age of widespread antibiotic resistance. A network of gut immune and epithelial cells tolerates commensal microbes, while - retaining its ability to initiate a potent response upon pathogenic infection. Whether and how commensal gut microbes affect the capacity of immune system to fight enteric infection remains largely unknown. - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Israel - - - ILCSIGNALLING - - - H2020-MSCA-IF-2016 - - - 747114 - - - - - KOBENHAVNS UNIVERSITET - - - EUR 212 194,80 - - - Intestine-on-a-chip for investigating microbioal-epithelail interaction - - - EUR 212 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - The small intestine forms a barrier that protects us against the outer world. Here commensal bacteria are tolerated while pathogens are effectively fought off. Occasionally, however, pathogenic bacteria colonize the intestine - causing different diseases, which constitute a huge burden worldwide. The ability to study interactions of pathogenic bacteria with the intestine will provide new insights into the disease mechanisms, and new therapeutic targets and ways to prevent - disease occurrence. Current animal and 2D models based on tumor cell lines both have shortcomings as they react differently to pathogenic bacteria when compared to healthy human tissues. - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - iChip - - - H2020-MSCA-IF-2016 - - - 746270 - - - - - KATHOLIEKE UNIVERSITEIT LEUVEN - - - EUR 160 800 - - - Christian-Muslim families dealing with religious pluralism in everyday family lifeReligious reconstruction in religiously mixed marriages - - - EUR 160 800 - - - Belgium - - - Higher or Secondary Education Establishments - - Mixed families are both the index and agent of social change: they exemplify the increase in migration flows and provide us with an opportunity to analyse the everyday processes related to Europe’s growing pluralism. - Quantitative studies demonstrate that interfaith marriages lead to higher divorce rates, suggesting that the latter are due to communication difficulties and disagreements caused by cultural differences between partners, as well as to hostility from - families of origin, religious institutions and society at large. However, rather than being firmly and empirically established, these concepts remain mere assumptions and, as such, also conceal the ways in which those involved actively and - reflexively deal with these dynamics to prevent damage to their relationship. Much scholarly attention has focused on couples defined as Islamic-Catholic or Muslim-Christian, which represent a paradigmatic case study of “mixedness” that typically - incorporates differences pertaining to ethnicity, class and faith. The challenge of this project gives an empirically adequate exploration of a pattern firmly established in quantitative studies, i.e., that interfaith marriages give rise to high - divorce rates. This project thus aims to understand, through an in-depth qualitative study, the daily life of such families: what differences are responsible for tension between spouses, how they deal with this in order to avoid damage to their - relationship, and how gender interferes with these problems. Mixed marriages will be a key to examine the whole of society facing new family changes, Islam and religious diversity in everyday life. The research project addresses the EU lines of - Horizon 2020, studying one of the major challenges for an “inclusive and multicultural” Europe. The fellowship will provide me with wider competence, publications and connections necessary to apply for an ERC Grant in 2019. - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Belgium - - - ReMix - - - H2020-MSCA-IF-2016 - - - 747592 - - - - - UNIVERSITY OF YORK - - - EUR 195 454,80 - - - Uncovering the Transatlantic History of Turkey Husbandry and Breeding using a Multi-Disciplinary Approach - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - For 2000 years, turkeys (Meleagris gallopavo) have been kept and raised by indigenous cultures in North and Central America. In the late 15C, European travellers 'discovered' turkeys and quickly introduced them to Europe and - beyond. Their popularity has only increased over time, and in both continents, turkeys are now the most commonly raised bird after chicken. Investigations into the emergence of turkey breeding are fundamental to understanding the evolving economic - and symbolic relationships between humans and this iconic bird, as well as to provide historical challenges: first, the diversity of the specimens introduced in Europe (subspecies involved, geographic origin) is unknown; second, the diversity of - morphologically similar birds raised in the same time (chicken, guinea fowl, peacock) hamper the recognition of early turkeys from America. This research project will pair the zooarchaeological and morphometrics expertise of the applicant, Aurélie - Manin, with the biomolecular specialists in the BioArCh group at the University of York, UK, to document and explore turkey husbandry practices in Western Europe from 15C to 19C and its integration in pre-existing backyards. Using combined - morphometric and biomolecular analyses this project will: 1) document the origins and intensity of turkey breeding in Europe; and 2) explore the changing socio-economic role of turkeys as they spread through modern Western Europe. Fundamentally, the - results of this research will address both archaeological and food production issues by exploring the history of turkey husbandry and providing important data on the evolution of modern breeds, management practices and the resilience of modern - poultry industry. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - TURKEY - - - H2020-MSCA-IF-2016 - - - 748679 - - - - - KOBENHAVNS UNIVERSITET - - - EUR 212 194,80 - - - Propagating DNA Modifications Across the Cell Cycle - - - EUR 212 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - Background - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - DNAmod_PROPAGATION - - - H2020-MSCA-IF-2016 - - - 747332 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 195 454,80 - - - Sunlight driven carbon-dioxide reduction: Hybrid catalytic systems consisting of molecular catalysts and light-harvesting Quantum-dots and semiconductors - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Artificial photosynthesis, in which sunlight is directly used to generate fuels from CO2 and water, is an attractive solution to both global energy challenges and environmental issues caused by rising CO2 levels. However, - implementation of such a quasi-carbon-free fuel-economy requires efficient catalysts and light-harvester to power this uphill reaction. The proposed project is aimed at developing novel hybrid photocatalysts and photocathodes for light-induced CO2 - reduction using molecular catalysts and semiconductor light-harvesters. Molecular catalysts will be immobilized onto the semiconductor-materials to generate robust photocatalysts, and subsequently, these semiconductor-catalyst assemblies will be - transferred to transparent electrodes to build photoelectrodes. The innovative aspect of CO2RED is to employ inexpensive, carbon-based semi-conducting ligh-harvesters (carbon-nitride, carbon quantum dots) and 3d-metal based molecular catalysts, and - use robust linkages to interface them with transparent photoelectrodes. Finally, this hybrid photocathode will be tested in a tandem CO2/H2O photoelectrochemical cell by coupling it with a photoanode for water oxidation. The project being at the - interface of synthetic, materials, photo- and electro-chemistry, will provide an excellent opportunity for the experienced researcher (ER) to develop a wide range of technical skills. In addition, the fellowship will allow the ER to gain important - complementary skills including proposal writing, manuscript preparation, public outreach, networking, and IPR protection that will be invaluable for his independent career. The combination of the cutting-edge science and training excellence of the - project will greatly improve the ER’s career prospect and enhance the host group’s international reputation. - - 2020-02-29, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - CO2RED - - - H2020-MSCA-IF-2016 - - - 745604 - - - - - STICHTING KATHOLIEKE UNIVERSITEIT - - - EUR 260 929,80 - - - Emerging Visual Expectation in the Brain - - - EUR 260 929,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Falling raindrops will likely move downwards; red brake lights up ahead will predict a car slowing down. While perception of the world around us feels rich in detail, our brains lack the capacity to analyze every ‘pixel’ at - every time-point. Instead, the brain relies on expectations to compress the total amount of sensory information from the environment. A failure to rely on expectations about visual inputs would lead to catastrophic consequences. For example, an air - traffic controller without the ability to predict the likely trajectories of two planes coming in for landing would spell certain disaster. Remarkably, despite the obvious role in adaptively guiding behavior, the cognitive and neural mechanisms - supporting perceptual expectations remain poorly understood. I will concurrently measure human behavior and neural responses to address two fundamental, yet outstanding questions: How are expectations about visual input acquired, and what is the - impact of behavioral relevance? I anticipate mechanisms of expectation to change with learning and behavioral relevance. For example, driving in the rain, expectations about break lights could amplify this immediately relevant information. - Expectations about falling rain, on the other hand, could support the equally important task of suppressing this irrelevant information so you may return home safely. - - 2020-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Netherlands - - - EXPECTATION - - - H2020-MSCA-IF-2016 - - - 743941 - - - - - UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN - - - EUR 175 866 - - - Algebraic Covering Codes Enabling Network Transmissions - - - EUR 175 866 - - - Ireland - - - Higher or Secondary Education Establishments - - Applications of rank-metric codes arise ever more frequently in network communications problems, and yet their mathematical theory is still in its infancy. To date attention has almost exclusively focussed on very special - classes of codes and their generalizations. - - - 2020-04-30, Grant Agreement signed - - - 2018-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Ireland - - - ACCENT - - - H2020-MSCA-IF-2016 - - - 740880 - - - - - UNIVERSITY OF YORK - - - EUR 195 454,80 - - - Quantum Energy Conditions and Singularity Theorems - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The proposed project explores an important open question in mathematical physics today: the occurrence of singularities in spacetime - places where the usual understanding of physics breaks down. For example, singularities may - exist at the center of black holes, or have occurred at the beginning of the universe. Singularity theorems, developed over the past 50 years following pioneering work of Penrose and Hawking, are mathematically rigorous results that imply that - singularities are inevitable provided the matter content of the universe obeys a suitable energy conditions. Although forms of matter described by quantum field theory can violate the original energy conditions, recent developments provide hope that - singularity theorems can be proved even in this case. To date, however, no known singularity theorem fully corresponds to the behaviour of quantum fields or takes into account the backreaction of the quantum field on the spacetime. The goal of this - project is to establish singularity theorems for quantised matter using recent work by the researcher and the supervisor as a base. This will be approached in several ways (a) new quantum energy inequalities will be proved that are suitable for use - in singularity theorems; (b) new singularity theorems will be proved using a transversely smeared version of the averaged null energy condition; (c) analogues of singularity theorems will be investigated in the context of semiclassical gravity. The - combination of the complementary expertise of the researcher and the supervisor is essential to the success of this project. Moreover the researcher will receive training from the supervisor in mathematically rigorous approaches to quantum field - theory and relativity, which will broaden her knowledge and expertise. This project will help to resolve a major problem in mathematical physics today and provide insight into how the universe works. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - QuEST - - - H2020-MSCA-IF-2016 - - - 744037 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 1 868 855 - - - Perceptual encoding of high fidelity light fields - - - EUR 1 868 855 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - One of the grand challenges of computer graphics has been to generate images indistinguishable from photographs for a naïve observer. As this challenge is mostly completed and computer generated imagery starts to replace - photographs (product catalogues, special effects in cinema), the next grand challenge is to produce imagery that is indistinguishable from the real-world. - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - EyeCode - - - ERC-2016-COG - - - 725253 - - - - - KOBENHAVNS UNIVERSITET - KOBENHAVNS UNIVERSITET - - - EUR 1 758 742 - - - Chemical Tools for Unravelling Sirtuin Function - - - EUR 1 758 742 - - - Denmark - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - It was recently realized that lysine acetylation affects a wide variety of cellular processes in addition to the initially recognized histone related gene regulation. Together with recent groundbreaking results, revealing the - presence of additional acyllysine modifications, the basis for a paradigm shift in this area was formed. Examples of enzymes formerly thought to be lysine deacetylases, have been shown to cleave these new types of lysine modification and members of - the sirtuin class of enzymes play a central role. - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Denmark - - - SIRFUNCT - - - ERC-2016-COG - - - 725172 - - - - - KOBENHAVNS UNIVERSITET - - - EUR 200 194,80 - - - BIOlogical SignaTures of AnhydrobioSIS via comparative transcriptomics on different evolutionary lineages within tardigrades - - - EUR 200 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - The current proposal revolves around the dehydration induced state, anhydrobiosis - a survival strategy found among a range of life-forms in face of severe desiccation. Anhydrobiosis is defined by a reversible shut-down of - metabolism (biostasis) and it seems to involve adaptations at all levels of organismic organization. The current proposal uses tardigrades as a model to gain novel insight into molecular signatures underlying this unique biological phenomenon. - Several molecules have been implicated in the anhydrobiotic mechanism; however, so far studies have been returning contradictory results with respect to the differential expression of genes in pre- and post-anhydrobiotic phases. Interestingly, our - preliminary, unpublished data from Møbjerg lab suggest that there could be lineage specific strategies to anhydrobiosis. Consequently, I will use transcriptome sequencing (RNAseq) and ddPCR to reveal key-player genes and characterize functional - pathways involved in i) different stages of anhydrobiosis of single tardigrade species and ii) between different evolutionary lineages within the phylum. The mentioned methods constitute the most important training element of my project. The overall - goal of the proposal is to determine potential gene expression signatures for anhydrobiosis establishing a transcription profile that is i) characteristic of a particular physiological state and ii) that could possibly reflect the phylogenetic - position of a taxon. My previous extensive experience on phylogenetic and molecular dating methods will, in this respect, be utilized to estimate the chronology of the possible diversification of anhydrobiosis within evolutionary lineages. My - research will be conducted at the Møbjerg lab, which represents one of the world’s leading groups in the field of tardigrade biology. The group is situated at the Department of Biology, University Copenhagen, which is a superbly equipped institution - with a high international profile. - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - BIOSTASIS - - - H2020-MSCA-IF-2016 - - - 747087 - - - - - THE UNIVERSITY OF EDINBURGH - THE UNIVERSITY OF EDINBURGH - - - EUR 139 986 - - - Portable Characterisation of Sperm Motility - - - EUR 139 986 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Based on an ongoing ERC project on characterising and studying the motility of highly-idealised, model micro-swimmers, we have built and validated a first-generation portable prototype device for assaying accurately bull sperm - motility. To move to a more advanced prototype requires integrated software and hardware development and the setting up of standard protocols to render the measurement procedure robust for non-expert operators. Such a device, with integrated hardware - and software, for Portable Characterisation of Sperm Motility (PorCSperM) will assembled and applied to bull semen in this project, but is in principle applicable to other animals, and perhaps also to human fertility. - - 2018-09-30, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - United Kingdom - - - PorCSperM - - - ERC-2016-PoC - - - 727774 - - - - - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - - - EUR 1 928 400 - - - Relocating Modernism: Global Metropolises, Modern Art and Exile - - - EUR 1 928 400 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Breaking new ground, METROMOD proposes a rewriting of modern art history as a history of global interconnections, spurred by migration movements and rooted in cities. Revising the historiography of modern art, which still - continues to be dominated by the hegemonic and normative narratives of (Western) European Modernism and ignores the significance of exile movements, METROMOD conceptualizes art history as a result of interrelations and negotiations in global contact - zones, unstable flows, transformations and crises. In its analysis, METROMOD focuses on the first half of the 20th century. During this era the modern movement emerged as a paradigm in art and architecture, and rapid urbanization took place globally; - thousands of persecuted European modern artists fled their homes, re-establishing their practices in metropolises across the world. Reflecting both the geographical extent of these exile movements and their local urban impact METROMOD examines 6 key - migrant destinations—the global cities of London, New York, Buenos Aires, Istanbul, Shanghai and Bombay (now Mumbai)—following three main objectives: to explore transformations in urban topographies, identifying artistic contact zones and places of - transcultural art production; to investigate networks of exiled and local artists as well as collaborative projects and exhibitions; and to analyse art publications and discourse generated in centres of exile. Digital mapping will locate sites of - artistic migration in the cities and demonstrate linkages between transforming metropolises and flows of people and objects around the world. The conceptual triangle of modernism, migration and the metropolis forms the foundation of an innovative - comparative, interdisciplinary methodology. As well as impacting art history, METROMOD will provide a historical perspective from which today’s mass migration movements can be better understood. - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - METROMOD - - - ERC-2016-COG - - - 724649 - - - - - INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE - INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE - - - EUR 1 998 750 - - - Robust algorithms for learning from modern data - - - EUR 1 998 750 - - - France - France - - - Research Organisations - Research Organisations - - Machine learning is needed and used everywhere, from science to industry, with a growing impact on many disciplines. While first successes were due at least in part to simple supervised learning algorithms used primarily as - black boxes on medium-scale problems, modern data pose new challenges. Scalability is an important issue of course: with large amounts of data, many current problems far exceed the capabilities of existing algorithms despite sophisticated computing - architectures. But beyond this, the core classical model of supervised machine learning, with the usual assumptions of independent and identically distributed data, or well-defined features, outputs and loss functions, has reached its theoretical and - practical limits. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - France - - - SEQUOIA - - - ERC-2016-COG - - - 724063 - - - - - KAROLINSKA INSTITUTET - KAROLINSKA INSTITUTET - - - EUR 2 279 406 - - - Targeting oxidative repair proteins for treatment of cancer and inflammation - - - EUR 2 279 406 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Oxidative damage and defects in DNA repair are frequently underlying many diseases, e.g., cancer, autoimmune diseases, ischemia/reperfusion injury, neurodegenerative disorders, viral diseases and ageing. Although some - molecular understanding into oxidative DNA lesions and repair proteins exist, a thorough understanding on the link to diseases is largely missing, and therapies exploiting oxidative DNA damage and repair have not emerged. Here, we will study - mechanisms of nucleotide metabolism and oxidative DNA damage and repair, and generate tools and make use of ‘omics’ approaches to explore the function of the Nudix and glycosylases family enzymes in relation to oxidative metabolism. Furthermore, we - will progress and understand the basic mechanisms how oxidative DNA lesions are processed and kill cells. Importantly, we will develop small molecule inhibitors targeting Nudix and glycosylases, e.g. MTH1, NUDT15 and OGG1, and use our newly developed - inhibitors to increase our knowledge of these enzymes in oxidative metabolism and disease. We will further optimize these inhibitors into drugs and explore therapeutic approaches in cancer and inflammation as well as in exploratory studies in a - variety of diseases involving oxidative stress. Altogether, in this programme we contribute to deepen our knowledge into the fundamental biology of oxidative stress and its links with disease, and providing the scientific community with an innovative - repertoire of selective inhibitors for numerous enzymes involved in repair of oxidative lesions. This will enable exploratory basic science discoveries as well as potential novel therapeutic interventions ‘outside the box’. The programme will also - generate high value to the industrial competitiveness of Europe in form of novel inhibitors for treatment of diseases. - - 2021-07-31, ongoing project - - - 2016-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Sweden - - - TAROX - - - ERC-2015-AdG - - - 695376 - - - - - KAROLINSKA INSTITUTET - KAROLINSKA INSTITUTET - - - EUR 2 500 000 - - - Functional connectome of brainstem circuits that control locomotion - - - EUR 2 500 000 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Locomotion is a complex motor act that is used in many daily life activities and is the output measures of a plethora of brain behaviors. The planning and initiation of locomotion take place in the brain and brainstem, while - the execution is accomplished by activity in neuronal networks in the spinal cord itself. Recent experiments have provided significant insight to the organization of the executive spinal locomotor networks. However, little is known about the - brainstem control of these networks. Here, I propose to provide a unified understanding of the functional connectome of the key brainstem networks that control locomotion in mammals needed to select appropriate locomotor outputs. To obtain these - goals we will develop a suite of transgenic mouse models with optogenetic or chemogenetic switches in defined populations of brainstem neurons combined with the possibility to use state-of-the-art cell-specific electrophysiological and anatomical - connectivity studies. We will reveal the functional organization of ‘go’ and ‘stop’ command systems in the brainstem that are directly upstream from the spinal locomotor networks and the mechanisms for how spinal networks are selected. We will - further functionally deconstruct the next network layer in midbrain structures that control the ‘go’ and ‘stop’ command systems. Our research takes a specific approach to provide mechanistic insight to the integrated movement function by building the - motor matrix in a functional chain from the locomotor–related spinal cord neurons that have been identified to midbrain neurons. A segment of our research will link these networks to locomotor impairments after basal ganglia dysfunction. The work has - the potential to make a breakthrough in our understanding of how complex movements are generated by the brain and has translational implications for patients with movement disorders. It will push boundaries in the universal effort that aims to - comprehend how brain networks create behaviors. - - 2021-07-31, ongoing project - - - 2016-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Sweden - - - LocomotorIntegration - - - ERC-2015-AdG - - - 693038 - - - - - KAROLINSKA INSTITUTET - KAROLINSKA INSTITUTET - - - EUR 1 493 125 - - - Therapeutic and Biomarker Potential of long non-coding RNAs in Vascular Disease - - - EUR 1 493 125 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The contribution of cardiovascular disease to human morbidity and mortality continues to steadily increase in our aging European society. In response, extraordinary efforts have been launched to determine the molecular and - pathophysiological characteristics of its etiology. The collective work of multiple research groups has uncovered a complex transcriptional and post-transcriptional regulatory milieu, which is believed to be essential for maintaining cardiovascular - homeostasis. Recently, non-coding RNAs, especially the ones with antisense capabilities such as microRNAs or ‘natural antisense transcripts’ (NATs) have received much attention. They have been identified as important transcriptional and - post-transcriptional inhibitors of gene expression. - - - 2021-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Sweden - - - NORVAS - - - ERC-2015-STG - - - 679777 - - - - - KAROLINSKA INSTITUTET - KAROLINSKA INSTITUTET - - - EUR 2 480 889 - - - Restoration of tumor suppressor function by induction of translational read-through of premature termination codons - a strategy for improved cancer therapy - - - EUR 2 480 889 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Tumor suppressor genes such as TP53, RB1, PTEN and APC are frequently inactivated in sporadic and inherited human tumors. A significant fraction of the mutations in these genes are nonsense mutations that lead to premature - termination of translation and expression of truncated unstable and non-functional proteins. We will identify and characterize novel molecules that can induce translational read-through of premature termination codons in nonsense mutant TP53 and - expression of full length p53 protein. Hits will be tested for their effect on nonsense mutant RB1, PTEN and APC. We will also elucidate the molecular mechanism of action of the identified compounds by CETSA and other techniques. Moreover, we will - test hit compounds on primary tumor cells from patients ex vivo, and generate mouse knock-in tumor models with nonsense mutant tumor suppressor genes for further characterization of hits. We will take the most promising hits through preclinical - development towards clinical trials. Our aim is to develop novel and efficient targeted therapy for tumors with nonsense mutations in the TP53, RB1, PTEN and/or APC tumor suppressor genes. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Sweden - - - TRANSREAD - - - ERC-2015-AdG - - - 694825 - - - - - KAROLINSKA INSTITUTET - KAROLINSKA INSTITUTET - - - EUR 1 895 155 - - - Reversing the epigenetic state of oligodendrocyte precursors cells in multiple sclerosis - - - EUR 1 895 155 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Oligodendrocytes (OL) are glial cells that mediate myelination of neurons, a process that is defective in multiple sclerosis (MS). Although OL precursor cells (OPCs) can initially promote remyelination in MS, this regenerative - mechanism eventually fails in progressive MS. OPCs go through several epigenetic states that ultimately define their potential to differentiate and myelinate. OPCs in progressive MS stall in a distinct epigenetic state, incompatible with - differentiation and remyelination. We hypothesize that these OPCs regress to an epigenetic state reminiscent of the state of embryonic OPCs, which remain undifferentiated. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Sweden - - - EPIScOPE - - - ERC-2015-CoG - - - 681893 - - - - - UNIVERSITY OF SOUTHAMPTON - - - EUR 183 454,80 - - - Muslim Antisemitism in Colonial Morocco - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - European colonialism in Muslim societies represented a turning point for the powerful European influence that was widespread throughout the Middle East. With European Jews acquisition of land in Palestine, Arab nationalism - started to incorporate antisemitic ideology into their texts and discourses. The creation of the Jewish state in 1948 accelerated this process. Thus, paradoxically, while the presence of antisemitism among European societies has been marginal since - the end of World War II, socially and politically discredited, and even prosecuted, antisemitic voices have gained ground in the Middle East. With the immigration of the North African populations (both Jewish and Muslim) from the second half of the - twentieth century, some conflicts have arisen in Europe as well, particularly, but not exclusively, in France. Therefore, the colonial period is crucial to understanding not only when, how and why European antisemitism entered northern Africa, and - later returned to Europe, but above all how it interacted with the local notions and prejudices about Jews in Muslim societies. Further research is required to analyse in detail what the integration of a foreign ideology means and involves for native - popular ideas and local prejudices. In this research project, the researcher will address these issues through historical anthropology and ethnography in the context of inter-religious relations in Spanish Colonial Morocco. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - MORA - - - H2020-MSCA-IF-2016 - - - 745752 - - - - - KAROLINSKA INSTITUTET - KAROLINSKA INSTITUTET - - - EUR 1 422 338,77 - - - Shaping of the Human Immune System by Primal Environmental Exposures In the Newborn Child - - - EUR 1 422 338,77 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Immune systems are highly variable, but the sources of this variation are poorly understood. Genetic variation only explains a minor fraction of this, and we are unable to accurately predict the risk of immune mediated disease - or severe infection in any given individual. I recently found that immune cells and proteins in healthy twins vary because of non-heritable influences (infections, vaccines, microbiota etc.), with only minor influences from heritable factors (Brodin, - et al, Cell 2015). When and how such environmental influences shape our immune system is now important to understand. Birth represents the most transformational change in environment during the life of any individual. I propose, that environmental - influences at birth, and during the first months of life could be particularly influential by imprinting on the regulatory mechanisms forming in the developing immune system. Adaptive changes in immune cell frequencies and functional states induced - by early-life exposures could determine both the immune competence of the newborn, but potentially also its long-term trajectory towards immunological health or disease. Here, I propose a study of 1000 newborn children, followed longitudinally during - their first 1000 days of life. By monitoring immune profiles and recording many environmental influences, we hope to understand how early life exposures can influence human immune system development. We have established a new assay based on Mass - Cytometry and necessary data analysis tools (Brodin, et al, PNAS 2014), to simultaneously monitor the frequencies, phenotypes and functional states of more than 200 blood immune cell populations from only 100 microliters of blood. By monitoring - environmental influences at regular follow-up visits, by questionnaires, serum measurements of infection, and gut microbiome sequencing, we aim to provide the most comprehensive analysis to date of immune system development in newborn children. - - 2021-06-30, ongoing project - - - 2016-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Sweden - - - Born-Immune - - - ERC-2015-STG - - - 677559 - - - - - KAROLINSKA INSTITUTET - KAROLINSKA INSTITUTET - - - EUR 1 950 033 - - - Prosaposin and GPR37 in synucleinopathies - - - EUR 1 950 033 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The next breakthrough in the treatment of synucleinopathies, incl Parkinson´s disease (PD), will be aimed at interference of disease progression based on insights into the underlying pathogenic process. The pathological - hallmark of PD are Lewy bodies (LBs), in which α-synuclein is the major constituent together with other PD-linked gene products (DJ-1, LRRK2, parkin, and GBA) and aggregated GPR37. GPR37 is exceptional among GPCRs having a high propensity for - intracellular receptor accumulation and aggregation leading to neurotoxicity. However, unexpectedly, our results suggest that GPR37 is neuroprotective in dopaminergic when located at the plasma membrane. Consistently, prosaposin (PSAP), and its - neurotrophic fragment prosaptide, were recently identified as agonists at GPR37. PSAP is a neuroprotective protein that regulates intracellular lysosomal enzyme function, with saposin C being a co-factor of GBA. In addition, we hypothesize that PSAP - is secreted following cellular stress and, via membraneous GPR37, cue dopamine neurons to initiate survival pathways. Pivotal to this programme is modeling and analysis of the atomic structures of GPR37 in complex with prosaptide, which will grossly - facilitate mechanistic understanding and drug development with potential use in diagnosis and treatment. Novel applications and technological advancements of fluorescence correlation spectroscopy will be implemented for single molecule trafficking of - GPR37 and its ligands and will examine whether GPCR multimerization beyond dimer formation may be neurotoxic. Normal and cGPR37KO mice will be virally transduced by α-synuclein to delineate in the relative contributions of improved lysosomal function - versus GPR37 agonism for neuroprotection by prosaptides. Evolving from the autopsy studies that anti–GPR37 label LBs and that prosaposin is released upon cellular injury, we will develop GPR37 ligands as PET tracers for LBs in synucleinopathies. - - 2020-07-31, ongoing project - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Sweden - - - PROGSY - - - ERC-2014-CoG - - - 649116 - - - - - KAROLINSKA INSTITUTET - KAROLINSKA INSTITUTET - OXCIA AB - - - EUR 150 000 - - - COmmercializing first-in-class dCTPase Inhibitors for treatment of hematological Cancers - - - EUR 150 000 - - - Sweden - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - In our ERC grant GEnetic NEtworks as a tool for anti-CAncer Drug Development we used siRNA screening and genetic networks to identify dCTPase being involved in DNA repair and replication. Further studies revealed that dCTPase - plays a role in the degradation of nucleoside analogues used in cancer treatment. We then used an RNAi approach to validate dCTPase as a target to improve nucleoside analogue therapy. The dCTPase protein was purified and we set up an enzymatic - high-throughput assay to screen >65,000 compounds, which generated hits that inhibit dCTPase (IC50~1-10μM). Using in house medicinal chemistry we developed TH1217, a low nM potent and selective dCTPase inhibitor with favourable pharmacokinetic - properties. TH1217 synergistically induces apoptosis and cell death in combination with cytidine analogue treatment in cancer cells in vitro and in vivo, but shows no increased toxicity in nontransformed dividing cells. Here, we want to explore the - commercial potential of the dCTPase inhibitors identified in the ERC grant. - - 2017-06-30, closed project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2015 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Sweden - - - CODIC - - - ERC-2015-PoC - - - 692908 - - - - - UNIVERSITY OF LEEDS - - - EUR 195 454,80 - - - Vulnerable trait-combinations in corals and fishes and their management - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Vulnerable trait-combinations in corals and fishes and their management (Traits coRals fIshes Management) - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - United Kingdom - - - TRIM - - - H2020-MSCA-IF-2016 - - - 747102 - - - - - UNIVERSIDAD DE OVIEDO - UNIVERSIDAD DE OVIEDO - - - EUR 1 459 219 - - - Nano-optics on flatland: from quantum nanotechnology to nano-bio-photonics - - - EUR 1 459 219 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Ubiquitous in nature, light-matter interactions are of fundamental importance in science and all optical technologies. Understanding and controlling them has been a long-pursued objective in modern physics. However, so far, - related experiments have relied on traditional optical schemes where, owing to the classical diffraction limit, control of optical fields to length scales below the wavelength of light is prevented. Importantly, this limitation impedes to exploit the - extraordinary fundamental and scaling potentials of nanoscience and nanotechnology. A solution to concentrate optical fields into sub-diffracting volumes is the excitation of surface polaritons –coupled excitations of photons and mobile/bound charges - in metals/polar materials (plasmons/phonons)-. However, their initial promises have been hindered by either strong optical losses or lack of electrical control in metals, and difficulties to fabricate high optical quality nanostructures in polar - materials. - - - 2021-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Spain - - - 2DNANOPTICA - - - ERC-2016-STG - - - 715496 - - - - - KAROLINSKA INSTITUTET - KAROLINSKA INSTITUTET - - - EUR 149 693 - - - Validation of a conceptually new treatment for glioblastoma multiforme with an IP protected small molecule - - - EUR 149 693 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Glioblastoma multiforme (GBM) is the most aggressive form of brain cancer with marginal life expectancy even with the most aggressive available therapy. We have identified a previously unanticipated vulnerability of GSCs which - when targeted, leads to a rapid and complete cell death of all tumor cells isolated from nine different patients diagnosed with GBM. The cellular mechanism has been identified and involves an increased vulnerability of GSCs to massive vacuolization - which can be induced by a small molecule, termed Vacquinol-1. The vacuolization results from an induction of massive macropinocytosis leading to cytoplasmic membrane rupture and cell death. Vacquinol-1 reduces viability in vitro with approximately 70 - times greater potency than current chemotherapy and efficiently and significantly reverses disease and prolongs survival in animal models of human GBM. Vacquinol-1 is highly selective for glioblastoma cells and is not present in other examined cell - types, including astrocytes from the brain. Vacquinol-1 has favorable pharmacokinetics, oral bioavailability and exhibits excellent overall preclinical characteristics. Synthetic chemical expansion of Vacquinol-1 reveals an exquisitely delicate - structure activity relationship. IP protection has been filed. In order to be able to validate this discovery into an innovation and possible commercialization we need to: 1) Compare potency and efficacy with competing compounds in development stage. - 2) Establish optimized dosage regimen from in vitro and in vivo cytotoxicity and brain exposure measurements. 3) Develop a GMP-compatible stereo-selective synthesis of an appropriate Vacquinol-1 isomer for amending composition of matter to patent and - pre-GLP/GLP toxicological and phase I clinical trials. 4) Together with Karolinska Institutet Innovations AB protect the intellectual property, validate commercialization potential and establish a development plan. - - 2016-08-31, closed project - - - 2015-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2014 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Sweden - - - GlioVac - - - ERC-2014-PoC - - - 637047 - - - - - JOHN INNES CENTRE - - - EUR 183 454,80 - - - Unravelling the molecular Basis of epigenetic silencing: what factors define a gene as a Polycomb target? - - - EUR 183 454,80 - - - United Kingdom - - - Research Organisations - - The current lack of mechanistic understanding regarding how Polycomb targets are selected severely limits the potential for epigenetic manipulation in many eukaryotic systems. This proposal therefore addresses a key central - question in chromatin biology: which factors specify a gene for Polycomb mediated silencing? - - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - AMBITION - - - H2020-MSCA-IF-2016 - - - 753000 - - - - - KAROLINSKA INSTITUTET - KAROLINSKA INSTITUTET - - - EUR 1 923 060 - - - Revealing Allele-level Regulation and Dynamics using Single-cell Gene Expression Analyses - - - EUR 1 923 060 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - As diploid organisms inherit one gene copy from each parent, a gene can be expressed from both alleles (biallelic) or from only one allele (monoallelic). Although transcription from both alleles is detected for most genes in - cell population experiments, little is known about allele-specific expression in single cells and its phenotypic consequences. To answer fundamental questions about allelic transcription heterogeneity in single cells, this research program will focus - on single-cell transcriptome analyses with allelic-origin resolution. To this end, we will investigate both clonally stable and dynamic random monoallelic expression across a large number of cell types, including cells from embryonic and adult - stages. This research program will be accomplished with the novel single-cell RNA-seq method developed within my lab to obtain quantitative, genome-wide gene expression measurement. To distinguish between mitotically stable and dynamic patterns of - allelic expression, we will analyze large numbers a clonally related cells per cell type, from both primary cultures (in vitro) and using transgenic models to obtain clonally related cells in vivo. - - 2020-06-30, ongoing project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Sweden - - - Allelic Regulation - - - ERC-2014-CoG - - - 648842 - - - - - UNIVERSITE GRENOBLE ALPES - - - EUR 173 076 - - - Amorphous Precursors in Biomineralization. - - - EUR 173 076 - - - France - - - Higher or Secondary Education Establishments - - Calcium carbonate (CaCO3) is a widely studied inorganic compound very abundant in nature as a mineral and a biomineral. It is an important building block of biological bodies, making up the structure of invertebrate organisms. - CaCO3 is also a key compound for CO2 sequestration strategies. Recent investigations have reported a so-called non-classical pathway for CaCO3 formation, which involves the formation of an amorphous precursor: amorphous calcium carbonate (ACC), which - acts as an intermediate in the formation of the final CaCO3 crystalline polymorphs (calcite and aragonite). This has been reported for biominerals such as the sea urchin spicules, which are made of calcite and the shells of Haliotis tuberculata made - of aragonite. However, despite these advances on the characterization of the amorphous precursor, little is known about the polymorph selection mechanism. Amorphous carbonates have also been discovered in several strains of cyanobacteria some of - these cyanobacteria mineralize CaCO3 internally even in solutions that are under-saturated with respect to all CaCO3 polymorphs. These cyanobacteria have the ability of concentrating elements from the culture medium in the amorphous carbonates. They - have also shown chemical selectivity, and interesting core-shell chemical distributions of some ions such as Ba2+, Ca2+ and Sr2+. These carbonates may serve as a storage reservoir of Ca and inorganic C for the cells if they can be stable on one hand - under certain conditions but easily remobilizable as well on the other hand. However, the structural characteristics of these carbonate formations inclusions and their impact on the crystallization pathway are poorly known. Therefore, the goal of - this project is to shed light into the role of the AAC in the (bio)mineralization process. This aim will be tackled under two approaches abiotic and biogenic induced conditions, which correspond to the two different parts proposed for the development - of this project. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - AMORPREBIO - - - H2020-MSCA-IF-2016 - - - 747597 - - - - - DB SYSTEMTECHNIK GMBH - - - EUR 100 018,80 - - - Acoustic monitoring of railway track quality - - - EUR 100 018,80 - - - Germany - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The need for reduced costs and higher system reliability will make condition-based maintenance a key technology in the railway sector in the nearer future. However, reliable and adequate methods for monitoring track - conditions, preferably by adding monitoring devices to ordinary rolling stock, are still far from being in place. The proposed project focuses on acoustic track monitoring and aims at pushing forward this monitoring technique to a point, where track - faults such as squats, deteriorated rail joints or hanging sleepers can be automatically detected and quantified. This is achieved by combining advanced measurement techniques - involving sound pressure signals due to radiation from rail and wheel as - well as axle box vibrations – with advanced simulation techniques for wheel/rail interaction. DB Systemtechnik GmbH as my host supplying all needed measurement techniques and myself as expert in the modelling of wheel/rail interaction will meet and - utilize synergy effects from merging our competences in order to design and implement a methodology for acoustic track monitoring that is clearly beyond today's state-of-the-art. Furthermore, being an active member of the group at DB Systemtechnik - will give me access to experience, knowhow and education in the railway technology sector. This is a unique possibility for me to broaden my career profile. It will make me an attractive employee both in the railway technology sector as well as in - academia. Crossing the boarders of academia and preparing myself for leadership during my fellowship will be a strong support for my goal to become a research leader in academia. It will widen my professional network and offer a possibility for - strong cooperation beyond the lifetime of the project. - - 2019-06-30, Grant Agreement signed - - - 2018-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-SE - Society and Enterprise panel - - - Germany - - - AMONTRACK - - - H2020-MSCA-IF-2016 - - - 744605 - - - - - THE FRANCIS CRICK INSTITUTE LIMITED - - - EUR 183 454,80 - - - RAS/C-RAF interaction: A new pharmacological target in Kras-driven lung cancer. - - - EUR 183 454,80 - - - United Kingdom - - - Research Organisations - - Lung adenocarcinoma is the most frequent subtype of lung cancer and patients harbour activating mutations in the KRAS gene in approximately 25% of the cases. Unfortunately, regardless of the outcome of recent studies - identifying specific KRASG12C inhibitors, so far, oncogenic KRAS is not a druggable target yet. The best-characterized KRAS effector pathway, the ERK cascade consists of RAF, MEK and ERK proteins that can be inhibited with small molecules targeting - their kinase activities. As the development of RAF and MEK kinases inhibitors progressed, feedback loop reactivating the ERK cascade have emerged, inducing resistance to treatment. Thus, new innovative strategies are needed to achieve a more - long-term inhibition of this signalling pathway, while reducing detrimental side effects due to MAPK inhibition in normal cells. It has been described more than 20 years ago that RAF directly interacts with RAS through its Ras Binding Domain (RBD), - and many research groups have been trying to disrupt this interaction developing allosteric inhibitors as a cancer therapy. At the moment, those molecules need to be improved in order to achieve a strong inhibition of this pathway. Surprisingly, no - mouse model actually demonstrates the requirement of RAS/RAF interaction during KRAS-induced lung tumourigenesis. Here, we propose to investigate this crucial question using a new mouse model allowing us to conditionally disrupt RAS/RAF interaction - in vivo. Using the leading mouse model to study lung cancer (LSL-KrasG12D/+; p53-/- mice), we will take advantage of both Cre/LoxP and FLIPo/Frt technologies to investigate the role of RAS/RAF interaction during lung tumours maintenance, as well as - its function in tumour/host crosstalk and normal physiology. All together, these investigations will provide important insights into the clinical relevance of developing RAS interaction inhibitors for the treatment of RAS-driven tumours. - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - IVORIaN - - - H2020-MSCA-IF-2016 - - - 748273 - - - - - CENTRALESUPELEC - CENTRALESUPELEC - - - EUR 149 682,86 - - - CacheMire: Wireless Edge Caching Platform - - - EUR 149 682,86 - - - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Mobile data traffic sharply increases each year, due to the rich multi-media applications, video streaming, social networks, and billions of connected users and devices. This increasing mobile data traffic is expected to reach - by 2018 roughly 60% of total network traffic. In this regard, caching contents at the edge of the network, namely at the base station and user terminals, is a promising way of offloading the backhaul (especially crucial in dense network deployments) - and decreasing the end-to-end content access delays, since the requested contents become very close to the users. Therefore, caching has the potential to become the third key technique for wireless systems sustainability. The goal of this proof of - concept is to realize a prototype of such an architecture which enables caching at the edge of the network, and called as “CacheMire”. In particular, we shall focus on development of the first version of CacheMire, which aims to 1) provide an - application programming interface (API) to website developers (or content providers); 2) build a set of software/hardware tools to track/collect users' content access statistics under privacy constraints and regulations; 3) and design a storage - unit/box for caching strategic contents (i.e., images, videos, files, news) at the base stations and access points. In addition, we aim to combine advanced physical layer techniques with caching so that resources in the uplink/downlink of next - generation 5G wireless networks can be further optimized. - - 2018-11-30, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - France - - - CacheMire - - - ERC-2016-PoC - - - 727682 - - - - - STOCKHOLMS UNIVERSITET - STOCKHOLMS UNIVERSITET - - - EUR 1 967 755 - - - Understanding the speed limits of magnetism - - - EUR 1 967 755 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - While the origin of magnetic order in condensed matter is in the exchange and spin-orbit interactions, with time scales in the subpicosecond ranges, it has been long believed that magnetism could only be manipulated at - nanosecond rates, exploiting dipolar interactions with external magnetic fields. However, in the past decade researchers have been able to observe ultrafast magnetic dynamics at its intrinsic time scales without the need for magnetic fields, thus - revolutionising the view on the speed limits of magnetism. Despite many achievements in ultrafast magnetism, the understanding of the fundamental physics that allows for the ultrafast dissipation of angular momentum is still only partial, hampered by - the lack of experimental techniques suited to fully explore these phenomena. However, the recent appearance of two new types of coherent radiation, single-cycle THz pulses and x-rays generated at free electron lasers (FELs), has provided researchers - access to a whole new set of capabilities to tackle this challenge. This proposal suggests using these techniques to achieve an encompassing view of ultrafast magnetic dynamics in metallic ferromagnets, via the following three research objectives: - (a) to reveal ultrafast dynamics driven by strong THz radiation in several magnetic systems using table-top femtosecond lasers; (b) to unravel the contribution of lattice dynamics to ultrafast demagnetization in different magnetic materials using the - x-rays produced at FELs and (c) to directly image ultrafast spin currents by creating femtosecond movies with nanometre resolution. The proposed experiments are challenging and explore unchartered territories, but if successful, they will advance the - understanding of the speed limits of magnetism, at the time scales of the exchange and spin-orbit interactions. They will also open up for future investigations of ultrafast magnetic phenomena in materials with large electronic correlations or - spin-orbit coupling. - - 2022-01-31, ongoing project - - - 2017-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Sweden - - - MAGNETIC-SPEED-LIMIT - - - ERC-2016-STG - - - 715452 - - - - - UNIVERSIDAD POMPEU FABRA - UNIVERSIDAD POMPEU FABRA - - - EUR 149 750 - - - Emulating visual perception of contrast for image capture, post-production and synthesis - - - EUR 149 750 - - - Spain - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - A significant research outcome from the IP4EC ERC Starting Grant has been to propose a vision model for contrast perception that can be realized as an image-dependent non-linear transformation that can accurately reproduce the - detail and contrast directly visible in a scene. The model is based on findings from psychophysical and neurophysiological studies and is well suited to the statistics of natural images. The resulting transform is automatic (no need for user-selected - parameters) and of extremely low computational complexity, making it a good candidate for real-time applications. It produces images and videos that look natural, without any halos, spurious colors or artifacts. The model has been validated through - psychophysical tests that confirm that it outperforms other state of the art algorithms in terms of users’ preference. A European patent application has been filed. - - 2018-03-31, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Spain - - - VIPERCON - - - ERC-2016-PoC - - - 727255 - - - - - KAROLINSKA INSTITUTET - KAROLINSKA INSTITUTET - - - EUR 1 941 531 - - - Understanding microbe-induced stomach cancer – the key to a workable strategy for worldwide prevention - - - EUR 1 941 531 - - - Sweden - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Stomach cancer is the 4th most common cancer and 2nd leading cause of cancer-related death worldwide. The aim of this proposal is to deepen the understanding of mechanisms involved in microbe-induced gastric carcinogenesis, - which will facilitate risk stratification for identification of high-risk groups and may offer new opportunities for pharmacological and probiotic prevention. We hypothesize that novel H. pylori genotypic variation can predict carcinogenicity. The - cancer-causing H. pylori strains may no longer be present at the time of cancer diagnosis, displaced by a changed microenvironment and invading microorganisms. We further hypothesize that the composition of invading microorganisms determines the risk - of stomach cancer. To test these hypotheses, we will perform a case-control study nested within a historic cohort of patients with gastric biopsies taken decades ago. For cases who developed stomach cancer several years after index biopsy and their - matched controls, paraffin-embedded blocks will be retrieved for metagenomic analysis of H. pylori and other microfloras, using our new method with laser capture micro-dissection, DNA amplification and sequencing. Interactions of host response and - environmental exposures with the gastric microbiome will also be checked. To explore the molecular mechanism underlying the gastric carcinogenesis, we will further examine gastric epigenetic changes and mutation profiles by novel methods which - require minute amount of starting material. Moreover, we will develop non-invasive tests for infections with carcinogenic strains of H. pylori and other microorganisms, which can easily be deployed in low-resource countries. This project will not - only contribute significantly to reducing the worldwide burden of this dreaded malignancy, but also broaden our understanding of the mechanisms linking infection, inflammation and cancer development, and open a door for research using the vast - resources of archived pathology materials. - - 2021-06-30, ongoing project - - - 2016-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Sweden - - - PreventStoCan - - - ERC-2015-CoG - - - 682663 - - - - - OBSERVATOIRE DE PARIS - UNIVERSITY OF DURHAM - MICROGATE SRL - PLDA SAS - - - EUR 3 760 793,75 - - - Green Flash, energy efficient high performance computing for real-time science - - - EUR 3 760 793,75 - - - France - United Kingdom - Italy - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The main goal of Green Flash is to design and build a prototype for a Real-Time Controller (RTC) targeting the European Extremely Large Telescope (E-ELT) Adaptive Optics (AO) instrumentation. The E-ELT is a 39m diameter - telescope to see first light in the early 2020s. To build this critical component of the telescope operations, the astronomical community is facing technical challenges, emerging from the combination of high data transfer bandwidth, low latency and - high throughput requirements, similar to the identified critical barriers on the road to Exascale. With Green Flash, we will propose technical solutions, assess these enabling technologies through prototyping and assemble a full scale demonstrator to - be validated with a simulator and tested on sky. With this R&D program we aim at feeding the E-ELT AO systems preliminary design studies, led by the selected first-light instruments consortia, with technological validations supporting the designs - of their RTC modules. Our strategy is based on a strong interaction between academic and industrial partners. Components specifications and system requirements are derived from the AO application. Industrial partners lead the development of enabling - technologies aiming at innovative tailored solutions with potential wide application range. The academic partners provide the missing links in the ecosystem, targeting their application with mainstream solutions. This increases both the value and - market opportunities of the developed products. A prototype harboring all the features is used to assess the performance. It also provides the proof of concept for a resilient modular solution to equip a large scale European scientific facility, - while containing the development cost by providing opportunities for return on investment. - - 2018-09-30, ongoing project | - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.2."> - - - FETHPC-1-2014 - HPC Core Technologies, Programming Environments and Algorithms for Extreme Parallelism and Extreme Data Applications - - - RIA - Research and Innovation action - - - France - - - greenFLASH - - - H2020-FETHPC-2014 - - - 671662 - - - - - THE FRANCIS CRICK INSTITUTE LIMITED - - - EUR 195 454,80 - - - SIngle-cell multi-OMICs approach to study intra-tumour heterogeneity of soft tissue Sarcomas - - - EUR 195 454,80 - - - United Kingdom - - - Research Organisations - - Recently, multi-omics approaches have led to a plethora of publications describing in detail the ‘omics landscapes of common cancer types. However, at the bulk tissue level, integrating different ‘omics layers remains an - uncompleted challenge. Soft tissue sarcomas are rare and often aggressive cancers of mesenchymal origin representing ~1% of all cancers but encompassing at least 50 subtypes. Hence, collecting enough of these rare samples for significant findings in - a timely fashion is the biggest hurdle. This issue can be addressed by repeating observations within individual patients to generate new hypotheses. Our long-term collaboration aims to obtain the genome, transcriptome and methylome of each of 1,000 - single-cells from 10 individual subtypes of soft tissue sarcomas. This design is possible thanks to DNA & RNA single-cell sequencing (SCS) of the same cell in Dr. Voet’s lab, and bespoke computational analyses in Dr. Van Loo’s lab, and access to - this rare material of Prof. Flanagan, lead for the sarcoma component of the Genomics England 100,000 Genomes Project. This proposal is the pilot project, where we focus on one malignant peripheral nerve sheath tumour, a rare aggressive cancer - originating from the connective tissues surrounding nerves. We will also sequence multiple regions of the primary tumour, the blood, and cell-free tumour DNA (ctDNA) before surgery and subsequently every three months. Prof. Flanagan’s group will - process the samples, and Dr. Voet will oversee the sequencing. In Dr. Van Loo’s lab, I will develop the computational tools to uncover the 3 ‘omics signals at the single-cell level that are averaged out in bulk tissues. SCS will shed light on the - fundamental links between cancer genomic subclones and the transcriptional and epigenetic diversity of cancer cell types; and we will answer whether ctDNA reflects the diversity of cancer cells and how it evolves in the course of treatment. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SIOMICS - - - H2020-MSCA-IF-2016 - - - 747852 - - - - - UNIVERSITE GRENOBLE ALPES - - - EUR 173 076 - - - Digital Edition of the Roman de Florimont - - - EUR 173 076 - - - France - - - Higher or Secondary Education Establishments - - The project aims to produce a digital scholarly edition of an overlooked text of the vernacular European Middle Ages: the Roman de Florimont, composed by Aymon de Varennes (Lyon, 1188). The edition will be complemented by a - methodological reflection on the feasibility of new digital tools versus the availability and applicability of existing ones with respect to medieval vernacular texts characterised by extreme linguistic variation. Indeed, Florimont has many unique - characteristics, starting from its Mediterranean setting, bringing together into a single plot both the two main narrative strands of the 12-13th century, the Breton and the Antiquity cycles; the result is an original Southern version of the French - chivalric roman. Furthermore, this thematic interest intersects with a remarkable linguistic relevance as the tradition includes witnesses related to two understudied linguistic domains: Franco-Provençal (the third French language, together with the - Langue d'Oil and the Langue d'Oc) and Franco-Italian (an artificial literary language). Despite this interest, Florimont has been almost entirely neglected by the scholarly community: only fifteen articles have been published on the subject and the - only existing edition (Hilka’s in 1932) is seriously flawed. The project will therefore produce an online multifaceted digital edition, exploiting existing tools for the support of stemmatics and linguistic analysis. Work on this text will then - represent an opportunity to reflect on the scholarly status of the digital edition, which is revolutionizing the traditional concept of the edition in the context of Romance Philology. The multidisciplinary character of this research and the planned - intensive training focused on Digital Humanities will allow the applicant to present herself to the academic world with a profile that is currently highly required but still not widely available: the Humanities researcher able to independently design - and manage a DH project. - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - DigiFlor - - - H2020-MSCA-IF-2016 - - - 745821 - - - - - UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6 - UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6 - OBSERVATOIRE DE PARIS - - - EUR 2 423 750 - - - Exploring the outer solar system beyond Neptune using stellar occultations - - - EUR 2 423 750 - - - France - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The solar system beyond Neptune’s contains largely unaltered material from the primordial circum-solar disk. It also kept the memory of the early planetary migrations, and thus contains essential information on the origin and - evolution of our planetary system. - - 2020-10-31, ongoing project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - France - - - LUCKY STAR - - - ERC-2014-ADG - - - 669416 - - - - - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - - - EUR 183 454,80 - - - Eco-lightweight granules for energy efficient applications - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Buildings in Europe are responsible for more than 40% of total energy consumption and 25% of carbon emissions, mainly due to the high number of old housing stock with very poor insulation systems. This research will develop - new energy efficient materials by engineering eco-lightweight granules (eco-LWG) to mitigate these problems. The eco-LWG will have high strength and high water absorption, ~100 wt.%, and be made from widely available waste materials: recycled mixed - coloured glass, clay and limestone. The eco-LWG will be used to contain phase change materials (PCM), which use chemical bonds to store and release heat, allowing control of temperature fluctuations. The high level of porosity in the eco-LWG will - allow them to absorb and retain much higher levels of PCM than has previously been possible using existing lightweight aggregates. Both the eco-LWG and the PCM loaded eco-LWG will be optimised by statistical design methodology and they will be used - to develop new energy efficient construction products. Two impregnation methods will be compared to introduce the PCM into the eco-LWG: vacuum sorption to achieve maximum PCM uptake and short term immersion to partially fill the connected porosity. - These will produce innovative lightweight and high heat-storage materials. Incorporating PCM loaded granules in mortars and other construction materials will result in reduced energy requirements to heat and cool buildings and improve indoor living - conditions. - - - 2017-07-31, Grant Agreement terminated - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - Eco-LWG - - - H2020-MSCA-IF-2014 - - - 658884 - - - - - UNIVERSITEIT UTRECHT - - - EUR 165 598,80 - - - Teneurin interactions in the neuronal synapse - - - EUR 165 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Synapses, connections between neurons, are critical to the formation of neural circuits. Functional neural circuits control intricate processes such as learning and memory, whereas failure in neural circuitry formation can - lead to developmental disorders including autism. - - 2018-12-31, Grant Agreement terminated - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - TEN-COMPLEX - - - H2020-MSCA-IF-2015 - - - 704070 - - - - - FONDATION NATIONALE DES SCIENCES POLITIQUES - - - EUR 173 076 - - - Lobbying and framing in foreign policy. EU and member states’ foreign policies towards Israel and Palestine - - - EUR 173 076 - - - France - - - Higher or Secondary Education Establishments - - LOBFRAM aims to advance our understanding of lobbying and framing in foreign policy in the European Union’s (EU) system of multi-level governance. While lobbying in the EU has received a lot of attention in recent years, - lobbying in foreign policy remains a largely under-researched topic. Therefore, this project will explore the activities of non-state actors (NSAs), such as business groups, NGOs and solidarity movements, in EU foreign policy, investigating the - networks that are established at different levels (EU and member states) and framing processes. The main contribution of LOBFRAM will be to investigate networks as transmitters of ideas. In turn, this will help us to analyse how frames are created, - get codified and become collective frames influencing foreign policy at both the EU and member state levels, as well as what mechanisms of mutual interaction exist between EU and national foreign policy positions. - - 2018-02-23, Grant Agreement terminated - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - LOBFRAM - - - H2020-MSCA-IF-2014 - - - 657949 - - - - - INSTITUTE OF MATHEMATICS AND INFORMATICS AT THE BULGARIAN ACADEMY OF SCIENCE - - - EUR 128 994 - - - Spectral Theory of Non-Selfadjoint Markov Processes with Applications in Self-Similarity, Branching Processes and Financial Mathematics - - - EUR 128 994 - - - Bulgaria - - - Research Organisations - - The project contextually sets up a novel framework to study the spectral-theoretical properties of classes of non-selfadjoint (NSA) operators related to Markov processes (MP) via their intertwining to a continuous path - selfadjoint (SA) MP. Conceptually, this means that the jumps of each class of NSA MP can be considered a perturbation of one SA MP realized by an intertwining kernel. This approach can have far-reaching consequences for understanding classes of MP as - the reduction to SA MP leads to well-studied objects whereas the spectral theory of NSA operators is far from understood. The price of that is the non-invertability of the intertwining kernels. This framework is explored and crystallized by a - challenging, detailed spectral-theoretical study of an enormous class of NSA operators directly arising from the key phenomenon of self-similarity and in duality from branching. This is achieved by a synergy of research fields complementing each - other to obtain the spectral properties of those operators culminating in the derivation of spectral expansions of the generated semigroups. As a result of this synergy, a number of tools and techniques with impact, including applications to fields - beyond the scope of the project, are derived. A particular development in the area of recurrent equations and special functions will be unexpectedly exploited to the effect of a comprehensive theoretical and applied study, including numerical - schemes, of key quantities in financial and insurance mathematics such as Asian options and perpetuities. A training-through-research in line with the fellow’s affiliation to the host institution and the proposed secondment will critically contribute - to the optimal completion of the proposal in terms of time, scope and quality. - - 2017-06-30, closed project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Bulgaria - - - MOCT - - - H2020-MSCA-IF-2014 - - - 657025 - - - - - THE UNIVERSITY OF LIVERPOOL - THE UNIVERSITY OF LIVERPOOL - Institute of Science and Technology Austria - - - EUR 1 820 865 - - - Selective Barriers to Horizontal Gene Transfer - - - EUR 1 820 865 - - - United Kingdom - United Kingdom - Austria - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Horizontal gene transfer (HGT) is a form of genic inheritance that occurs between individuals in a population or between species rather than from parent to offspring. HGT is most prevalent in bacteria, where it is an important - source of novel metabolic pathways, pathogenicity factors, and antibiotic resistance. - - 2020-05-31, ongoing project | - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - EVOLHGT - - - ERC-2014-CoG - - - 648440 - - - - - UNIVERSITY COLLEGE LONDON - - - EUR 195 454,80 - - - REGULATION OF NEURONAL GENE EXPRESSION THROUGH CHROMOSOME ARCHITECTURE - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - A remarkable feature of the brain is its ability to adapt to changing environmental conditions. Modulation of synaptic strength and neuronal circuitry underlies experience-dependent learning, and requires widespread changes in - gene expression. Following neuronal depolarisation, intracellular signalling results in rapid induction of many activity-regulated genes (ARGs). There are numerous interconnected levels of gene regulation; one critical aspect relates to the - three-dimensional conformation of chromosomes within the nucleus. Looping of genes to regulatory regions and to other genes is required for transcriptional activation in other cell types, but remains largely unexplored in neurons. In this proposal, I - will investigate how the genome architecture changes during neuronal depolarisation, and how this influences activity-induced transcription and neuronal plasticity. I will first map the genomic interactions of ARGs in neurons before and after - depolarisation. This experimental approach will allow identification of enhancer-promoter loops and multi-gene complexes in an unbiased manner. Single-cell imaging studies will be performed to quantify the frequency of interactions across individual - neurons. I will use super-resolution microscopy to simultaneously analyse multiple loci with high precision, providing unprecedented detail of gene interactions in response to neuronal activity. Finally, I will use genome editing to disrupt specific - chromosomal contacts and evaluate the transcriptional induction of associated genes. I will assess whether loss of genomic contacts affects dendritic growth, a process associated with neuronal plasticity and dependent on ARG induction, to understand - the biological implications of chromosome looping. The aim of this project is to discover novel molecular mechanisms that govern transcription during neuronal activation, which is critical in experience-dependent learning. - - 2018-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - United Kingdom - - - NGECA - - - H2020-MSCA-IF-2015 - - - 702327 - - - - - LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - - - EUR 269 857,80 - - - States, firms and, sustainable economic growth: A view from the periphery - - - EUR 269 857,80 - - - United Kingdom - United States - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Persistent socioeconomic cleavages between world-leading and late industrialising peripheral countries threaten the post-crisis recuperation and undermine the sense of solidarity necessary to address the world’s most pressing - challenges. Attenuating core-periphery asymmetries will be contingent on the ability of peripheral countries to generate sustainable economic growth, but there is no simple solution to achieve this. My project will address this challenge through a - direct analysis of the productive and institutional structures of the two largest and most diversified peripheral economies, Spain and Korea, between 1985 and 2011. Using detailed case-studies of three industries based on a modified Global Value - Chain methodology, the research will explore the character of state-firm interactions in these two countries and their role in shaping strategies for economic transformation as they upgraded from mid- to high-income economies. I will contend that - upgrading in Spain and Korea was based on three factors: proactive states, coherent state structures, and symbiotic or co-dependent state-firm interactions. However, I will show that variations in the strategic and financial resources of state and - firms, and in the influences of role-model countries, led Spain and Korea to pursue a different sectoral specialisation in complex services and manufacturing respectively. The research will be carried out at the University of California San Diego and - the London School of Economics. The output will consist of a monograph and three academic papers. This project will enhance my career prospects by establishing me as an expert in economic transformation, expanding my publication record, developing my - skills in international project management, and strengthening my international professional networks in the US and Asia. No less importantly, the results of the project will contribute to current European goals for smart, sustainable and inclusive - growth. - - 2020-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - PERIGROWTH - - - H2020-MSCA-IF-2016 - - - 747943 - - - - - UNIVERSITY COLLEGE LONDON - - - EUR 183 454,80 - - - Mineral weathering in the unsaturated zone from the molecular to macro scale - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - ""Mineral weathering in the unsaturated zone from the molecular to macro scale (DryMIN)" - - 2019-01-22, ongoing project - - - 2017-01-23 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - DryMIN - - - H2020-MSCA-IF-2015 - - - 701478 - - - - - UNIVERSITA CA' FOSCARI VENEZIA - - - EUR 168 277,20 - - - Sparse Composite Likelihood Inference in Count Time Series - - - EUR 168 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - The availability of many interesting datasets consisting of count time series has motivated a steadily increasing research activity towards the development of appropriate statistical models. Nowadays, a variety of time series - models constructed on the basis of the integer-valued property of count data is available. However, their practical usefulness is often limited because of difficulties to implement efficient estimation procedures. These difficulties grow - significantly when higher-order autoregressive and moving average terms are included in the model or when multivariate time series data are considered. The SCouT project aims to enhance the flexibility of time series models for counts and facilitate - their application to data characterized by complex dependence structures. To this end, the SCouT project proposes an innovative methodological approach that integrates two powerful statistical tools, that is sparsity techniques and composite - likelihood methods. The project will provide a unified framework for simultaneous order selection and estimation of autoregressive and moving average terms in count time series models, reducing considerably the computational burden of traditional - model selection approaches and improving the predictive performance of the fitted model. The potential of the suggested methodology will be further highlighted by investigating its extensions to spatial and spatio-temporal data that are usually - characterized by complex dependence structures. Such data are often met in the field of temporal and spatial analysis of public health surveillance data that will be the main application field of the project. The simultaneous order selection and - estimation procedure established by the SCouT project will offer great support to statistical methods for public health surveillance and significantly contribute to the achievement of the effective and timely detection of disease outbreaks. - - 2018-05-31, ongoing project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - SCouT - - - H2020-MSCA-IF-2015 - - - 699980 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 185 076 - - - Philosophical Foundations of Topological Explanations - - - EUR 185 076 - - - France - - - Research Organisations - - This project develops a philosophical account of a new kind of explanations that recently became prominent in neuroscience. On this approach, systems such as brain are represented as networks of their elements and their - interactions. The explanation is then given in terms of features of connectedness (that is why it is called topological) of a network representing a system. - - - 2018-05-31, ongoing project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - TOPEX - - - H2020-MSCA-IF-2015 - - - 703662 - - - - - UNIVERSITAET SIEGEN - UNIVERSITAET SIEGEN - - - EUR 1 673 875 - - - Temporal Quantum Correlations - - - EUR 1 673 875 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Correlations are central for our modern view on the foundations of quantum theory and applications like quantum information processing. So far, research concentrated on correlations between two or more particles. Indeed, for - this situation it is well established that spatial quantum correlations are a useful resource for tasks like quantum cryptography and quantum metrology. There are, however, other types of correlations in quantum mechanics, which arise if a sequence - of measurements on a single quantum system is made. These temporal quantum correlations have recently attracted attention, because they are central for the understanding of some differences between the quantum and the classical world. Moreover, due - to experimental progress their observation has become feasible with trapped ions, polarized photons, or other quantum optical systems. - - 2021-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - TempoQ - - - ERC-2015-CoG - - - 683107 - - - - - CONSIGLIO NAZIONALE DELLE RICERCHE - CONSIGLIO NAZIONALE DELLE RICERCHE - UNIVERSITA DEL SALENTO - SCUOLA NORMALE SUPERIORE - - - EUR 1 993 908 - - - 4-Dimensional printing for adaptive optoelectronic components - - - EUR 1 993 908 - - - Italy - Italy - Italy - Italy - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project aims at developing four-dimensional printing of new adaptive systems, namely printing of complex, three-dimensional polymer objects embedding functional compounds and able to change or adapt their physical - properties responding to environmental stimuli. Additive manufacturing of three-dimensional objects relies on depositing or curing materials in a layer-by-layer fashion, starting from computer assisted design. These technologies have rapidly evolved - from laboratory research to commercially available desktop systems, with costs decreasing continuously. Notwithstanding such astonishing progress, the potentialities of three-dimensional printing are still poorly exploited in terms of both materials - and process resolution. This project will shed new light on the fundamental aspects of three-dimensional polymerization, thus establishing new process design rules and predictive tools for printing resolution. It will also specifically engineer - additive manufacturing for printing materials embedding active compounds, thus leading to real four-dimensional objects, namely structures that have three-dimensional features and time-changing physical properties at the same time. An integrated - approach will be pursued to this aim, where modeling and process engineering will be complemented by process monitoring, in order to establish well defined and reproducible methods for four-dimensional printing of photonic structures. The operation - of the adaptive components, for optical computing and data storage, will be based on their nonlinear response to optical inputs. Leading to a new and pioneering laboratory on four-dimensional printing technologies, this project will critically - consolidate scientific independence. - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Italy - - - xPRINT - - - ERC-2015-CoG - - - 682157 - - - - - OBSERVATOIRE DE PARIS - - - EUR 173 076 - - - UNVEILING THE NATURE OF PRIMORDIAL STARS - - - EUR 173 076 - - - France - - - Higher or Secondary Education Establishments - - "Understanding the nature of the first stars is a fundamental problem in Cosmology and Galaxy Formation. Numerical simulations suggest that primordial stars were more massive that present-day stars, and so they rapidly - disappeared. Heavy elements newly produced by these stars enriched the surrounding gas, out of which long-lived, low-mass stars formed. These "second-generation" stars survive until present-day, preserving in their photospheres the chemical imprint - of the first stars. In the Local Group, high-resolution spectroscopic studies, offer us the unique opportunity to reveal these fossil signatures. But second-generation stars are extremely rare, making their detection challenging. - - 2018-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - PRIMORDIAL - - - H2020-MSCA-IF-2015 - - - 700907 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 173 076 - - - Gemination Harmony - - - EUR 173 076 - - - France - - - Research Organisations - - The goal of this project is to investigate long-distance anticipatory effects from word-medial geminates across three unrelated languages – Italian, Tashlhiyt Berber and Japanese. In particular, it examines whether defining- - and enhancing- features associated with geminates are already anticipated on the non-adjacent word-initial consonant (e.g., whether in the Italian [palla] “ball” the properties of the word-medial [ll] geminate are already foreshadowed on the - word-initial [p]). In relation to the geminate-singleton distinction, Italian, Tashlhiyt Berber and Japanese present similarities (e.g. duration of the word-medial geminate consonant as primary correlate) and differences that are relevant for testing - the following issues a) the type of length-related vs. strength-related properties that are spread from the word-medial geminate to the word-initial consonant; b) the domain of the harmonic process, and more precisely, the role played by the - intervening vowel (e.g. the [a] in [palla]). In addition to the language factor, long-distance anticipatory effects induced by geminates will be tested against segmental factors (i.e. type of word-medial geminate consonant), prosodic factors (i.e. - focus) and performance-related factors (i.e. speech rate). Two acoustic and articulatory experiments (measurements of tongue-to-palate contact and intraoral pressure) will be designed to address these issues. The main contribution of this project - lies in determining the articulatory and acoustic bases of harmony as induced by gemination (‘gemination harmony’) within a cross-linguistic perspective. As such, it may provide important insights into the interplay between phonetics and phonology - and have crucial implications for the understanding of long-distance effects in speech production. - - 2017-08-31, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - GeHa - - - H2020-MSCA-IF-2014 - - - 661530 - - - - - ISTANBUL TEKNIK UNIVERSITESI - - - EUR 145 845,60 - - - Deep Learning UAV Networks for Autonomous Forest Firefighting - - - EUR 145 845,60 - - - Turkey - - - Higher or Secondary Education Establishments - - Thousands of hectares of forest lands are lost to wildfires every year. Utilization of Unmanned Aerial Vehicles (UAVs) is an efficient tool for fighting fires, however the state-of-the-art techniques lack in ability to predict - fire spread direction and coordinate multiple UAVs to suppress the fire under limited communication. DUF project aims to apply powerful tools from artificial intelligence domain to UAV firefighting problem, creating an innovative solution for - autonomous firefighting, which will reduce the amount of lands lost to fires. DUF will use the deep learning techniques for estimating the fire spread direction from infrared camera streams obtained from UAVs. Deep learning is a mature technology for - classical image recognition, but the use of deep learning to learn predictive models for fire spread is a novel approach. After the model is learned, a decentralized approximate dynamic planning algorithm will be utilized to coordinate UAV actions - for suppressing the fire. The algorithm development, simulations and first phase of the flight experiments will be conducted at Istanbul Technical University (ITU) Aerospace Research Center (ARC). The project will conclude with flight tests conducted - on natural forest fires, with operational support from Forest of Ministry of Turkey. Prof. Ure earned his Ph.D. degree from Massachusetts Institute of Technology, working on advanced UAV projects and collaborating with leading researchers in the - world. He has extensive experience on autonomous systems and published more than 30 critically acclaimed journal and conference papers in this subject. Prof. Ure is currently working as assistant professor in ITU and through this innovative - multidisciplinary research and with the help of experimental infrastructure provided by the ITU, Prof. Ure is expected to gain maturity in managing research projects and advance his career toward being an esteemed professor in the field of - aeronautics and artificial intelligence in Europe. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Turkey - - - DUF - - - H2020-MSCA-IF-2016 - - - 752669 - - - - - UNIVERSITY OF LEEDS - - - EUR 183 454,80 - - - Applying risk communication strategies to reduce speeding-related risks - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - In the EU, road accidents are in the top three causes of deaths and hospitalizations . WHO finds it crucial to discourage speeding, because it is a main cause of road accidents. The Fellow’s research in the psychology of human - factors engineering shows that people underestimate the risks of accidents from speeding and overestimate how much time is saved through speeding. Public campaigns have typically not yet sought to correct these misunderstandings but rather have - focused on emotional fear-appeals to reduce speeding. The Supervisor’s work on risk communication provides a systematic method for correcting such decision-relevant beliefs, which has been successfully applied to a variety of contexts, but not to the - design of dashboard tools. We take the novel approach of combining the Fellow’s and Supervisor’s fields to design dashboard tools and public campaigns that discourage intentions to speed by correcting drivers’ misunderstandings of the risks and - benefits of speeding. This project will benefit from Fellow's experience in leading projects on informing driver perceptions with dashboard tools, and her ongoing partnerships with the car industry and governmental agencies. The project will lead to - knowledge transfer between the Fellow’s Swedish Transportation Institute, partners at Volvo Cars and government agencies as well as the Supervisor’s Centre for Decision Research and the associated Institute for Transport Studies at the University of - Leeds (UK). The project will boost the Fellow’s academic career progression, as she aims to become a world-leading expert in evidence-based interventions that improve driver safety and save drivers’ lives. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - Speedingrisk - - - H2020-MSCA-IF-2015 - - - 706553 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - - - EUR 248 063,40 - - - Systematic search of RegulAtory elements coNtrOlling autosomal Monoallelic expression - - - EUR 248 063,40 - - - Ireland - - - Higher or Secondary Education Establishments - - Autosomal monoallelic expression (MAE) is an epigenetic phenomenon that controls the relative expression of maternal and paternal alleles in thousands of mammalian genes. Despite MAE’s widespread character the molecular - mechanisms involved in its establishment and maintenance are yet to be clarified. Recent work shows that the sets of genes subject to MAE are highly consistent across individuals and conserved between human and mouse species. I propose to test that - such conservation is due to specific regulatory elements in the genome associated with MAE genes. The strategy to discover such elements is via a systematic analysis of differences in genome-wide MAE patterns. In the outgoing phase of the Fellowship, - I will be based in DFCI under the supervision of Prof. A. Gimelbrant. There, I will experimentally map MAE patterns in mice with highly divergent genomic backgrounds and identify loci that consistently differ between strains in whether they are MAE. - Using computational methods, I will then determine whether particular motifs are associated with such variable regions. I will further assess the role of the candidate regulatory elements using specific F1 crosses and targeted mutagenesis. The - analysis in the mouse will be complemented by comparative analysis of human and chimp matched cells, in order to narrow down the candidate loci list and shed light on the evolution of MAE. Successful completion of this project will establish the - first model of genetic control of MAE and open doors to progress in the mechanistic and developmental understanding of MAE. On return to the TCD, under the supervision of Prof. A. McLysaght, I will be the link between two laboratories with a diverse - research focus that would not be collaborating unless in the context of this Fellowship. I will emerge from this collaborative work with new skills commensurate with a leading independent researcher in the EU. - - 2020-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Ireland - - - RANdOM - - - H2020-MSCA-IF-2016 - - - 752806 - - - - - CENTRUM ASTRONOMICZNE IM. MIKOLAJAKOPERNIKA POLSKIEJ AKADEMII NAUK - CENTRUM ASTRONOMICZNE IM. MIKOLAJAKOPERNIKA POLSKIEJ AKADEMII NAUK - OBSERVATOIRE DE PARIS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSIDAD DE CONCEPCION - - - EUR 2 360 500 - - - A sub-percent distance scale from binaries and Cepheids - - - EUR 2 360 500 - - - Poland - Poland - France - France - Chile - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - - We propose to carry out a project which will produce a decisive step towards improving the accuracy of the Hubble constant as determined from the Cepheid-SN Ia method to 1%, by using 28 extremely rare eclipsing binary systems - in the LMC which offer the potential to determine their distances to 1%. To achieve this accuracy we will reduce the main error in the binary method by interferometric angular diameter measurements of a sample of red clump stars which resemble the - stars in our binary systems. We will check on our calibration with similar binary systems close enough to determine their orbits from interferometry. We already showed the feasibility of our method which yielded the best-ever distance determination - to the LMC of 2.2% from 8 such binary systems. With 28 systems and the improved angular diameter calibration we will push the LMC distance uncertainty down to 1% which will allow to set the zero point of the Cepheid PL relation with the same accuracy - using the large available LMC Cepheid sample. We will determine the metallicity effect on Cepheid luminosities by a) determining a 2% distance to the more metal-poor SMC with our binary method, and by b) measuring the distances to LMC and SMC with an - improved Baade-Wesselink (BW) method. We will achieve this improvement by analyzing 9 unique Cepheids in eclipsing binaries in the LMC our group has discovered which allow factor- of-ten improvements in the determination of all basic physical - parameters of Cepheids. These studies will also increase our confidence in the Cepheid-based H0 determination. Our project bears strong synergy to the Gaia mission by providing the best checks on possible systematic uncertainties on Gaia parallaxes - with 200 binary systems whose distances we will measure to 1-2%. We will provide two unique tools for 1-3 % distance determinations to individual objects in a volume of 1 Mpc, being competitive to Gaia already at a distance of 1 kpc from the Sun. - - 2021-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Poland - - - CepBin - - - ERC-2015-AdG - - - 695099 - - - - - UNIVERSITA DEGLI STUDI DI PADOVA - UNIVERSITA DEGLI STUDI DI PADOVA - CONSIGLIO NAZIONALE DELLE RICERCHE - - - EUR 1 432 890 - - - a Theoretical chemistry Approach to tiME-resolved molecular Plasmonics - - - EUR 1 432 890 - - - Italy - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - Ultrafast spectroscopy is a powerful tool able to disclose the atomistic real-time motion picture of the basic chemical events behind technology and Life, such as catalytic reactions or photosynthetic light harvesting. - Nowadays, by cleverly harnessing the interaction of the studied molecules with plasmons (collective electron excitations supported, e.g., by metal nanoparticles) it is becoming possible to focus these investigations on specific nanoscopic regions, - such as a portion of a catalytic surface or of a photosynthetic membrane. This coupling can also produce new quantum effects such as molecule-plasmon hybrid excitations. On the other hand, it makes the real-time molecular evolution and its - perturbation by light more complex, and thus calls for new theoretical treatments. The available ones are unable to tackle this complexity, because they consist of phenomenological models focused on field enhancements or on generic features of the - various plasmon-molecule coupling regimes. The goal of TAME-Plasmons is to develop a theoretical chemistry approach to directly simulate the real time evolution of molecules interacting with plasmons and light. Our approach lifts the current - theoretical limitations by coupling a real-time quantum chemical description of the molecules with a time-dependent electromagnetic description of plasmons, rooted in our previous work on steady-state molecular plasmonics. We will implement this - approach in an open-source software, accessible also to non-specialists. We will address current open issues such as the controversial nature of plasmon-aided frequency up-conversion by noble gases and the interpretation of sub-molecularly resolved - photoemission induced by scanning tunneling microscopy. We will also anticipate questions that may arise along with progress in the field, for example how to engineer energy transfer paths in photosynthetic light harvesting proteins by exploiting the - coupling to plasmons. - - 2021-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Italy - - - TAME-Plasmons - - - ERC-2015-CoG - - - 681285 - - - - - THE UNIVERSITY OF WESTMINSTER LBG - THE UNIVERSITY OF WESTMINSTER LBG - - - EUR 1 497 212 - - - MONSOON ASSEMBLAGES - - - EUR 1 497 212 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The ambition of this cutting edge research project is to deliver a ground breaking, interdisciplinary design-driven inquiry into the impacts of changing monsoon climates in three of South Asia’s rapidly growing cities. This - will be undertaken at a time when climate change and urban development conspire to produce unlikely futures for urban survival. Extreme weather events, all attributed to the monsoon’s capricious nature, are resulting in increasing frequency in water - shortages, power failures, floods, out-breaks of disease, damage to property and loss of life. In responding to these events, the project will challenge the dominant view of the monsoon as a natural meteorological system outside of and distinct from - society. Instead it will propose that the monsoon is a co-production of physical and social dynamics entangled within historic lived environments that can be analyzed, worked with, shaped and changed. To do so, an unconventional interdisciplinary - team will develop a novel research methodology around the new operative concept of ‘monsoon assemblages.’ This will bring together the spatial design disciplines with the environmental humanities to advance research of lived environments as - indivisibly natural, social and political and to propose models for intervening in them through design. - - - 2021-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - MONASS - - - ERC-2015-STG - - - 679873 - - - - - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - - - EUR 187 419,60 - - - Advanced In-situ Techniques for the Development of Metal Oxide Nanostructures. - - - EUR 187 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - Complex metal oxides (MO) are the center of interest in a range of fields, with one of the most exciting applications being artificial photosynthesis. Converting solar energy into chemical bonds, once perfected, might - constitute a large part of a solution to the energy sustainability problem modern society faces. Semiconductor MOs have been shown to be promising candidates for light absorbers in anodes of photoelectrochemical cells used for water cleavage and - hydrogen production from sunlight. Candidate materials with optimal band gap and band alignment with water redox level used in such devices are often selected based on combinatorial material science techniques (inkjet printing, co-sputtering) and - theoretical calculations. Once a compound is identified as having promising photoelectrochemical properties, a fabrication route is sought to prepare nano-structured thin films. Colloidal chemistry is a highly promising approach for the synthesis of - complex MO nano crystals (NCs), in principle allowing control over the size and structure of the NCs by choosing appropriate precursors and tuning the conditions (temperature, time, reagent concentration, organic ligands). These advancements greatly - facilitate research in the field of complex functional materials and are now a standard, but the optimization of synthesis-by-design of NCs and thin films fabrication has been lacking and mainly based on a trial and error approach. With NanoAID we - will address this important issue and develop a comprehensive toolbox for synthesis and characterization of complex oxides, which will go beyond the state of the art with precise defects and non-stoichiometry control capabilities. NanoAID will focus - on developing a toolbox for rapid structural and morphological characterization of complex oxide NCs and thin films, and thermodynamic analysis of the involved compounds. Research will center on ternary and quaternary compounds, namely Cu/Mn-V-O. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - NanoAID - - - H2020-MSCA-IF-2016 - - - 753124 - - - - - KATHOLIEKE UNIVERSITEIT LEUVEN - UNIVERSITAT POLITECNICA DE VALENCIA - - - EUR 100 000 - - - Distributed Network of Active Noise Equalizers for Multi-User Sound Control - - - EUR 130 937,50 - - - Belgium - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The project is aimed at developing a novel wireless acoustic sensor network (WASN) for multi-user active noise equalization without the need of using headsets. This system is formed by multiple active noise equalizers (ANEs), - which act as a node in a WASN-type set up and cooperate to simultaneously solve their node-specific noise equalization problems. By doing so, the proposed system can simultaneously ensure the auditory comfort of multiple users that are regularly - exposed to high noise levels. This is radically different from the current multi-user systems for ANE where each node aims at ensuring the auditory comfort of each passenger without cooperation. - - 2018-10-31, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-04-2016-2017 - FET Innovation Launchpad - - - CSA - Coordination and support action - - - Belgium - - - D-Noise - - - H2020-FETOPEN-4-2016-2017 - - - 754576 - - - - - UNIVERSIDAD DE BURGOS - - - EUR 158 121,60 - - - High throughput computing for accelerated photovoltaic material discovery: From materialdatabase to the new generation of photovoltaic materials. - - - EUR 158 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - This proposal combines synergistically the predictive power of quantum mechanical calculations with a high throughput framework for the accelerated photovoltaic material discovery. The main objective of the project is the - creation of a material database that contains no crystalline-complex materials, which can be potential candidate for the development of a new generation of photovoltaic material. The robustness of the project is reinforced by the secondment of Onyx - solar which will synthesis and characterize the most promising candidates to validate the methodology and optimize the process. The collaboration between ICCRAM researchers and facilities and the experience of the fellow in this multidisciplinary - field guarantee the ideal conditions for the success of the research and the development of new methodologies, infrastructures and knowledge that are highly linked to the roadmap described in Horizon 2020. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - HT PHOTO DB - - - H2020-MSCA-IF-2016 - - - 752608 - - - - - UNIVERSIDAD DE ZARAGOZA - - - EUR 158 121,60 - - - Nanoparticle-based immunization, a novel therapeutic strategy for amyotrophic lateral sclerosis - - - EUR 158 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - As the life span of the population extends, the prevalence of neurodegenerative diseases is rapidly increasing representing a considerable impact for the quality of life and economy of many countries worldwide. Most of these - diseases, including Amyotrophic lateral sclerosis (ALS) are currently considered as proteopathies, where some proteins (SOD1 in the case of ALS) adopt misfolded conformations prone to aggregate and cause cellular toxicity and motor neuron death. - Moreover, these proteins are secreted to extracellular media contributing to the widespread of the disease in a prion-like manner, by acting as scaffolds for the misfolding of endogenous proteins when uptaken by surrounding cells. The aim of NanoALS - is to bring together Neuro and Nanoscience fields to design a novel passive immunization therapy to target the misfolded SOD1 released into cerebrospinal fluid in ALS. It will be based on the systemic delivery of gold and PLGA nanoparticles - functionalized with specific antibodies against the different isoforms of misfolded SOD1. These nanoconstructs will bind the different aberrantly folded SOD1 forms preventing their reuptake by neighbouring cells and blocking the cytotoxic epitopes - exposed after misfolding. The multidisciplinary work program in NanoALS covers the synthesis of the functionalized nanoconstructs as well as validation of their therapeutic potential in neuronal cell lines and in the SOD1-G93A mouse model of ALS. - Immunization against misfolded extracellular proteins has showed an encouraging success in ALS mouse models and in recent clinical trials with Alzheimer patients. Optimizing the delivery systems and targeting different misfolded isoforms as well as - the active exploitation and dissemination strategy designed for NanoALS will maximize the benefits of these therapies both in ALS and other proteopathies. - - 2020-02-29, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - NanoALS - - - H2020-MSCA-IF-2016 - - - 752349 - - - - - KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW - - - EUR 177 598,80 - - - Epigenetic regulation of cardiac regeneration after injury. - - - EUR 177 598,80 - - - Netherlands - - - Research Organisations - - Cardiovascular disease is a leading cause of morbidity and mortality worldwide, and there is a constant and urgent need for novel, more effective therapies to treat it. Chronic tissue hypoxia, nutrient deprivation and - myocardial cell death are some of the factors contributing to ischemic heart disease (IHD), the most common cause of death from all cardiovascular diseases. Current therapeutic approaches are limited in their capacity to enhance cardiac regeneration - after injury. Toward novel selective therapies, it is important to gain a detailed understanding of pathways orchestrating cardiomyocyte proliferation during development and after injury. - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Netherlands - - - HeartATAC - - - H2020-MSCA-IF-2016 - - - 751988 - - - - - VALSTYBINIS MOKSLINIU TYRIMU INSTITUTAS FIZINIU IR TECHNOLOGIJOS MOKSLU CENTRAS - - - EUR 142 779,60 - - - Graphene-Manganite Nanostructures for Novel Pulsed Magnetic Field Sensors - - - EUR 142 779,60 - - - Lithuania - - - Research Organisations - - A two-way innovative approach of combining Graphene and novel La1-xSrxMn1-yCoyO3 manganite is proposed in this GRAMAS project in order to manufacture highly sensitive sensors, measuring pulsed magnetic field [0.5 – 60 T] - independently on its direction (so-called B-scalar sensors). Firstly, the Co3+ cations will be introduced into the Mn3+ sites in order to achieve a novel, nanostructured La1-xSrxMn1-yCoyO3 layers deposited on various substrates by MOCVD technique. - Secondly, the single/few-layers of Graphene will be transferred on the top of Co-doped manganite layers, since Graphene has a superior mobility of charge carriers which also increases the Magnetoresistance. In addition, Graphene layer will allow - indication of magnetic field direction respectively to manganite B-scalar sensors‘s plane. Moreover, the combination of manganite/Graphene is expected to open new potentials for the discovery of superior magnetotransport properties even at room - temperatures and increased sensitivity to magnetic field. - - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - Lithuania - - - GRAMAS - - - H2020-MSCA-IF-2016 - - - 751905 - - - - - UNIVERSITE LIBRE DE BRUXELLES - - - EUR 258 530,40 - - - Blockchain: a new framework for swarm RObotic Systems - - - EUR 258 530,40 - - - Belgium - - - Higher or Secondary Education Establishments - - Swarms of robots will revolutionize many industrial applications, from targeted material delivery to precision farming. However, the characteristics that make them ideal for certain future applications —robot autonomy, - decentralized control, collective emergent behavior, etc.— can also be an obstacle when transferring this technology from academic institutions to real-world problems. Blockchain, an emerging technology originating in the Bitcoin field, demonstrates - that by combining peer-to-peer networks with cryptographic algorithms a group of agents can reach an agreement on a particular state of affairs without the need for a controlling authority. Using a novel combination of blockchain technology and swarm - robotics systems, BROS will generate new models to address three fundamental issues by using the robots as nodes in a network and encapsulating their transactions in blocks: First, new security models and methods can be implemented in order to give - data confidentiality and entity validation to robot swarms, therefore making them suitable for trust-sensitive applications. Second, distributed decision-making and collaborative missions can be easily designed, implemented, and carried out by using - special transactions in the blockchain, which enable robotic agents to vote and reach agreements. Third, robots may be able to function in diverse and changing environments without any change in their control algorithm, if their operation corresponds - to different blockchains that use different parameters. In the initial stage, blockchain technology will be used as a main control plane in combination with novel large-scale robot simulation tools such as ARGoS. Finally, the feasibility of the - models obtained under the previous objective will be validated in real-robot swarms, outputting a prototypical system that can serve as initial step towards transferring the proposed techniques from the academia into the industry. - - 2020-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Belgium - - - BROS - - - H2020-MSCA-IF-2016 - - - 751615 - - - - - KOZEP-EUROPAI EGYETEM - - - EUR 134 239,20 - - - Migration Solidarity and Acts of Citizenship along the Balkan Route - - - EUR 134 239,20 - - - Hungary - - - Higher or Secondary Education Establishments - - The aim of this 24-month Fellowship is to explore how refugees and refugee solidarity groups along the “Balkan route” relate to and enact European citizenship. While the project of European citizenship is an unprecedented - political development, it has institutionally been modelled upon and reproduces national conceptualisations of citizenship, rights and identity. The research will undertake a comparative analysis of discourses and practices of refugees and - pro-refugee volunteers in both EU and non-EU sites, and of the way in which they challenge concepts and institutions of European citizenship derived from national models of membership. It will pay particular attention to the relationship between - “movement” and the constitution of new European political subjectivities. The main objectives of this study are (1) to engage in a critical examination of the processes and institutions of European citizenship with a specific focus on countries of - the “Balkan route”; (2) to develop a cross-national and cross-local perspective on solidarity practices with refugees that have emerged along the Balkan route; (3) to investigate “acts of citizenship” emerging from both EU and non-EU citizens in - relation to refugee mobilities and to assess their implication for European citizenship; (4) To develop analytical and theoretical frames to reflect on new politics of solidarity in Europe and the way in which they contest exclusionary readings of - Europe; and (5) to contribute to conceptual debates on citizenship, the governance of migration and social movements and solidarity in the EU and beyond. In the current context of uncertainty regarding the future of the EU, these questions appear of - rising urgency. This study proposes to address these issues through ethnographic research with a range of pro-refugee initiatives in Hungary, Serbia and Greece, three countries at the heart of the Balkan route yet which hold different historical and - political relationships to “Europe” and the EU. - - 2019-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Hungary - - - MigSol - - - H2020-MSCA-IF-2016 - - - 751866 - - - - - INSTITUTO VALENCIANO DE INVESTIGACIONES ECONOMICAS, S.A. - - - EUR 170 121,60 - - - Baltic Countries Capital, Labour, Energy, Material and Service inputs - - - EUR 170 121,60 - - - Spain - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The BALTIC KLEMS (Baltic Countries Capital, Labour, Energy, Material, Service inputs) project aims at developing methodology for the Baltic Countries for KLEMS (countries are missing information). It expands the actual EU - KLEMS and WORLD KLEMS framework and includes the role played by detailed intangible assets to productivity growth. The results obtained will enable: a) to up-to-date information in the EU KLEMS database; b) to perform comparative economic analysis - for different developed countries from two complementary perspectives: the determinants of productivity growth and the patterns of structural change; c) be beneficial for a set of EU countries (plus the USA) from the INTAN-Invest initiative as well - as from the SPINTAN project funded by the 7th Framework programme of the EU. This can be summarized in the following objectives: (1) to investigate the economic structures; (2) to group the countries and propose a taxonomy of consistent patterns; (3) - to develop a new methodology; (4) to investigate the main characteristics of detailed intangible capital impact on productivity growth; (5, 6) to measure, rank the detailed contributors; (7, 8, 9) to derive the main results emphasizing the main - policy implications. In order to achieve these goals WP1 is dedicated to researching the economic structures. WP2 is devoted to developing a methodology, to obtaining values, ranking. WP3 is dedicated to identifying the consistent paths of structural - changes and the determinants. WP4 is dedicated to dissemination, public engagement. WP5 is dedicated to the practical exploitation. WP6 is dedicated to the management. WP7 is dedicated to training, career development. The researcher had internship at - the host supervised during the doctoral studies. The supervisor is the coordinator of the SPINTAN project funded by the 7th Framework programme. The host performs the calculations for the case of Spain (EU KLEMS), a set of Latin American countries - (LA KLEMS, a part of WORLD KLEMS). - - 2019-09-17, ongoing project - - - 2017-09-18 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-SE - Society and Enterprise panel - - - Spain - - - BALTIC KLEMS - - - H2020-MSCA-IF-2016 - - - 751198 - - - - - EARLHAM INSTITUTE - EARLHAM INSTITUTE - THE SAINSBURY LABORATORY - - - EUR 1 499 997 - - - Mechanisms of Immune Receptor Diversification in Cereals - - - EUR 1 499 997 - - - United Kingdom - United Kingdom - United Kingdom - - - Research Organisations - Research Organisations - Research Organisations - - The plant immune system is innate – it is encoded in the germline. In natural pathosystems, plants efficiently deploy hundreds of immune receptors to detect and disarm rapidly evolving pathogens including viruses, bacteria, - nematodes, insects, fungi and oomycetes. Exactly how such receptor diversity can evolve is an elusive question with important practical ramifications. A central class of plant immune receptors, called Nucleotide Binding Leucine Rich Repeats proteins - (NLR), has been implicated in recognition of vastly diverse pathogen-derived effector molecules. An emerging paradigm of receptor diversification in plant genomes involves new gene fusions of receptors with host proteins that are normally targeted by - pathogen effectors. Such fusion receptors ‘bait’ pathogens and their integrated domains are thought to function as ‘decoys’ or ‘sensors’ that mediate pathogen recognition. I have recently demonstrated that the mechanism of generating new receptors - through gene fusions originated at least 500 million years ago in mosses and is common to all flowering plants. Here, I propose to decode the mechanisms of plant immune receptor diversification by gene fusions by studying diversity and functions of - immune receptors in grasses, a young highly diversified plant family that includes the three most important crops: maize, rice and wheat. My specific aims are to: - - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - MIREDI - - - ERC-2016-STG - - - 716233 - - - - - ELVESYS SAS - - - EUR 185 076 - - - Fully Integrated Technology based on quantitative polymerase chain reaction for the diagnosis of Urinal Tract Infection - - - EUR 185 076 - - - France - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The project aims at developing a low-cost and reliable microfluidic disposable chip and the corresponding plug-and-play operating system for fast point-of-care diagnosis of UTI (Urinary Tract Infection) disease. This project - will make the best of the competences of the ER (Experienced Researcher)'s strong background in mechanical/electrical engineering, microfluidics as well as in cell biology and Elvesys expertise in the Elvesys proprietary FASTGENE technology, the - world fastest qPCR (qualitative Polymerase Chain Reaction) technique which has already been tested on Anthrax and Ebola simulating agents. We will integrate bacteria lysis, DNA extraction and PCR module into a single plastic chip. In the scope of the - project, the prototype will be tested in simple situations. Once satisfactory results are obtained, it will be made ready for tests in real-case situations (urine sample) through existing collaborations between Elvesys and hospitals. The prototype - will be expected to provide a reliable diagnosis from the sample input to fluorescence readout in less than 30 minutes. This technology can be extended to other disease diagnostics as well thus contributing to solving the current EU needs for fast - point-of-care diagnostic technologies. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-SE - Society and Enterprise panel - - - France - - - FIT-UTI - - - H2020-MSCA-IF-2016 - - - 750999 - - - - - THE QUEEN'S UNIVERSITY OF BELFAST - - - EUR 255 349,80 - - - Women’s Plague Writing in Early Modern England - - - EUR 255 349,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - In a time when high-profile outbreaks such as zika and ebola frequently make news headlines, the proposed research project, ‘Women’s Plague Writing in Early Modern England’, provides an opportunity to interrogate how we - interpret medical writing, who talks about medical problems and how gender becomes entangled in outbreaks by looking to the past. ‘Women’s Plague Writing in Early Modern England’ will undertake a survey and analysis of women’s plague writing in - England from 1550 to 1700. A three-year Global Fellowship project with a two-year outgoing phase at the University of Toronto (UofT) and incoming phase at Queen’s University Belfast (QUB), the research action takes an interdisciplinary approach to - women’s plague writing across the early modern period in England. The research programme explores the medical humanities through the lens of literature in its historical context. This project will change the canon of plague writing, which has - hitherto focused on male-authored texts. Moving from the single outbreak focus seen in my first monograph, The Literary Culture of Plague in Early Modern England (forthcoming with Palgrave Macmillan), the outcome of the project makes the significant - leap to studying a period of plague writing, a bigger-scale picture, with a broad chronology that captures major plague outbreaks in 1592, 1603, 1625, 1630, 1636 and 1665. The project encapsulates a full-period picture of women’s interactions with - plague and medicine and the corresponding gendering of plague writing. It will examine how women discuss the disease and how this differs from male-authored texts. It will ask how the medium chosen for publishing a text, print or manuscript, impacted - how women discussed the disease. It will investigate how women’s understanding of plague was gendered and, more broadly, how the textual construction of pestilence was gendered in early modern England. - - 2020-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - Womenswriting - - - H2020-MSCA-IF-2016 - - - 750969 - - - - - UNIVERSITE D'AIX MARSEILLE - - - EUR 173 076 - - - Groundwater effects on coastal ecosystems - - - EUR 173 076 - - - France - - - Higher or Secondary Education Establishments - - Coastal lagoons host some of the most dynamic, diverse and productive ecosystems on Earth, which are subject to significant pressure from human activities. Hydrological land-ocean connectivity is a universally accepted - important driver of coastal ecosystems, but the ecological effects of groundwater and associated solute fluxes to coastal systems remain poorly understood for most of the world’s shores. The overall goal of GRECO is to evaluate the role that - groundwater fluxes play in the functioning and vulnerability of coastal lagoon ecosystems, by studying its effects on primary producers. This project encompasses a suite of innovative and interdisciplinary investigations aimed at (a) documenting the - spatio-temporal distribution of groundwater-derived freshwater and nutrient inputs to lagoons and the exposure of benthic communities to groundwater-borne nutrients; and (b) evaluating the groundwater-derived effects on lagoon primary productivity by - identifying the nutrient sources for primary production and the role of groundwater in lagoon ecological functioning. To these aims, two economically and ecologically important French lagoons with contrasting hydroecological conditions will be - investigated by using new methods for coastal groundwater studies: 3D hydrodynamic numerical modeling and nutrient stable isotope analysis in primary producers. The novel understanding of groundwater-ecological interactions derived from this project - will significantly advance the state-of-the art of groundwater studies in the coastal zone by providing direct evidences of ecological effects of groundwater discharge and by adding new methods to study groundwater implications. The results of GRECO - will allow closing a current gap in the fundamental understanding of coastal processes, improving our capacity to sustainably manage hydrological and ecological resources in the coastal zone. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - GRECO - - - H2020-MSCA-IF-2016 - - - 748896 - - - - - UNIVERSITAT DE GIRONA - - - EUR 158 121,60 - - - Force/position control system to enable compliant manipulation from a floating I-AUV - - - EUR 158 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - The aim of this project is the design and implementation of a control system for an intervention autonomous underwater vehicle (I-AUV), composed of an AUV equipped with a multi-degree-of-freedom (multi-DOF) manipulator, to - enable it to perform fully autonomous compliant underwater manipulation. During this fellowship the experienced researcher will implement algorithms based on dynamic control/force control and perform extensive experimental trials with the real - system, to present results beyond the state of the art. - - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - IAUVcontrol - - - H2020-MSCA-IF-2016 - - - 750063 - - - - - UNIVERSITY OF BRIGHTON - - - EUR 195 454,80 - - - Targeting Glioblastoma using Combinatorial Therapeutic Nanovaccine - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The proposal aims at the synthesis, characterisation and application of a novel therapeutic nanovaccine (TNVax) that holds multiple modules for targeting glioblastoma multiforme (GBM). The proposed TNVax formulation includes a - gold nanocage core encapsulating Temozolamide (TMZ), coated with an extremophilic bacterial polysaccharide, mauran functionalised with anti-PD-L1 antibody and anti-CD133 antibody. The us of NVax nanoparticles (NPs) offers a combinatorial approach in - killing GBM cells both by immuno- and chemo- therapeutically. Site-specific delivery of the payload will stimulate the host immune system and channel the immune cells to the target site. Functionalisation of the anti-PD-L1 antibody on - drug-encapsulated NPs would significantly alter the immune suppression caused by GBM cells on TNVax delivery. In addition to anti-PD-L1 antibody, the TNVax particles contain tumour specific monoclonal antibody that specifically recognizes CD133 - antigen and facilitates strong binding. This approach would enhance the amount of antitumour activity offered by multiple means and thereby leaving a strong immune response against GBM based on antigen-antibody interactions. TNVax NPs will be - synthesised and characterised using microscopic and spectroscopic techniques and then subjected to in vitro and in vivo evaluations. In vitro studies will be performed for drug release kinetics and cytotoxicity using immunofluorescence and FACS - analysis. Induction of immune response by TNVax NPs will be evaluated using macrophage activation, induction of T-cell activity and cytokine production under in vitro conditions. The pharmacokinetic and pharmacodynamic studies will be carried out and - histopathological examinations performed using appropriate murine models induced with GBM cell lines. The potential outcomes of the proposed studies will help patients who suffer from early and advanced GBM by eradicating the disease permanently and - leaving good immunological memory. - - 2019-10-01, ongoing project - - - 2017-10-02 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - GLIOMA - - - H2020-MSCA-IF-2016 - - - 749403 - - - - - OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN - - - EUR 166 156,80 - - - Government of Life and Death: The Rise of Coercive Power in European Late Prehistory - - - EUR 166 156,80 - - - Austria - - - Research Organisations - - CoPOWER will adopt state-of-the-art archaeological and bioarchaeological approaches to investigate the transition to urban society and the rise of increasingly sophisticated social control mechanisms in Europe 1200-500 BC. The - rich burial record of Austria and northeast Italy is used as a case study. Many research projects have investigated social complexity and urbanization in the study area by focusing on the elite groups that supposedly spearheaded these processes; by - contrast, CoPOWER will explore the life-histories of the marginal individuals that are often the forgotten victims of history. In doing so, it will (a) contribute to develop an analytical framework for identifying and assessing potential - bioarchaeological correlates of social change and disruption in the mortuary record of any given society and (b) promote marginality studies in archaeology. These aims will be achieved by building upon the ER's previous expertise in archaeological - theory, in conjunction with the new skills in human osteology, isotope and DNA analysis she will acquire over the MSCA. Through high-quality training at OREA and the Natural History Museum in Vienna, the ER will not only learn about human skeletal - biology and various analytical and laboratory procedures, but also how to interpret the data resulting from these methods within a broad, comparative anthropological framework for bioarchaeological problem-solving. Collaboration on OREA’s ECR-funded - project The Value of Mothers to Society will also provide crucial training in project management and added-value knowledge on the gender dimension of inequality in Europe’s late prehistory. The contributions of CoPOWER to understand the processes - leading to social change and marginality under socio-environmental stress are extremely timely in today’s worldwide order; its results 'will therefore fulfil the Horizon 2020 Programme’s aims to promote EU excellence through top research across - Europe and through a knowledge-based society. - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Austria - - - CoPOWER - - - H2020-MSCA-IF-2016 - - - 750596 - - - - - UNIVERSIDAD DE GRANADA - - - EUR 239 191,20 - - - Homogeneous and heterogeneous enantioselective Single Electron Transfer (SET) catalysis in cross-coupling reactions - - - EUR 239 191,20 - - - Spain - - - Higher or Secondary Education Establishments - - Chirality of organic molecules plays a paramount role in our society as a consequence of the direct relation between the absolute molecular configuration and many properties and applications of molecular compounds and - materials. The demand of enantiomerically pure compounds has increased considerably driven by the request of the pharmaceutical industry, as well as applications such as flavours, fragrances, and materials. In this context, the development of new - methodologies to obtain enantiomerically pure compounds has become a challenge for the scientific community. - - - 2021-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Spain - - - EnanSET - - - H2020-MSCA-IF-2016 - - - 749359 - - - - - EIDGENOESSISCHES DEPARTEMENT DES INNERN - - - EUR 187 419,60 - - - Unravelling species barriers of coronaviruses - - - EUR 187 419,60 - - - Switzerland - - - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - "Human coronaviruses (CoVs) are distributed worldwide and cause a significant percentage of all common colds. Most of these viruses presumably emerged through zoonotic transmission, have adapted to the human host, and are now - known to cause mild upper respiratory tract infections. However, the more recent zoonotic transmission of the highly pathogenic Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) - have demonstrated the potential of coronaviruses to also cause highly severe human diseases and are associated with a high mortality. The precise mechanisms that allow coronaviruses to jump across species barriers are only poorly understood. "COV - RESTRIC" aims to unravel species barriers of coronavirus infections and to uncover basic host cell mechanisms preventing a transmission across different species. We hypothesize that conserved restriction factors exist between different species which - limit viral replication and which need to be overcome via viral evasion and adaptation strategies in order to establish a zoonotic infection. These may include the lack or genetic incompatibility of essential viral replication co-factors as well as - the presence of antiviral restriction mechanisms. We will use two complementary genetic screening approaches to identify unknown coronavirus restriction factors. Once we have identified possible candidates, we will analyze them for their - cross-conservation employing coronaviruses from different species, such as human, bat and camel virus isolates, as well as the respective primary cell culture material originating from the authentic host. This approach will help to rigorously define - species barriers to viral transmission which should promote future development of preventive and therapeutic strategies to combat emerging RNA virus infections in humans." - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-SE - Society and Enterprise panel - - - Switzerland - - - COV RESTRIC - - - H2020-MSCA-IF-2016 - - - 748627 - - - - - UNIVERSITY OF LEEDS - - - EUR 195 454,80 - - - Pregnancy and Reproduction Organ-on-a-chip Models - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - PreTerm Birth (PTB) occurs before 37 weeks of gestation. Of 60,000 babies born prematurely every year in UK, ~1,400 die. Premature babies show increased risks of long term neurodevelopmental deficits and chronic diseases. - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - United Kingdom - - - PROM - - - H2020-MSCA-IF-2016 - - - 748903 - - - - - CHALMERS TEKNISKA HOEGSKOLA AB - - - EUR 178 993,80 - - - Modulated Composite Structures: A 3D Bulk Approach to Incoherent Hetero-Structure Interface Engineering in Oxides for Future Low Temperature Energy Applications - - - EUR 178 993,80 - - - Sweden - - - Higher or Secondary Education Establishments - - Interfaces between oxides can provide entirely new ways to realize novel properties. The goal of this research project is to further clarify the fundamental relationships between composition, crystal structure and ionic - transport properties in a novel system based on the hexagonal YMnO3 type structure. This system shows a remarkably large reversible - oxygen storage capacity (LR-OSC) at very low temperatures 150-400C, and the experienced researcher(ER) hypothesizes - that this transition may strongly depend on the energy related to the hetero-structure interface (HSI) formation that is naturally formed in modulated composite structures (MODCOMS); in this case between an YMnO3 and Y2Mn2O7 based structure in 3D - (i.e., throughout the bulk material). - - - 2020-02-29, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Sweden - - - MODCOMS - - - H2020-MSCA-IF-2016 - - - 748574 - - - - - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - - - EUR 187 419,60 - - - The role of the glucocorticoid receptor in dopaminoceptive neurons in mitochondrial dysfunction and vulnerability to depression - - - EUR 187 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - Depression is considered as a common mental illness worldwide affecting around 350 million people. Chronic stress is a major risk factor for its development. Interestingly, individuals can differ in the way of coping with - chronic stress and are either prone (vulnerable) or resistant (resilient) to develop depression. High anxiety-trait is a vulnerability factor to develop stress-induced depression. Furthermore, it was also linked with mitochondrial dysfunction in the - nucleus accumbens and in the establishment of social hierarchies in rodents. These observations suggest an important role of mitochondria in the vulnerability to develop stress-induced depression. The glucocorticoid receptor that is activated upon - stress was recently shown to regulate mitochondrial function and gene transcription. Our own data show that expression of the glucocorticoid receptor is altered in animals with high anxiety-trait correlating with the expression of several - mitochondrial genes. Thus, our central hypothesis is that vulnerability to develop depression is caused by a glucocorticoid receptor-mediated dysfunction of mitochondria in the nucleus accumbens. This project will address this idea in the mouse model - showing considerable individual differences in stress-induced psychopathology-like behavior. We will first examine the role of the glucocorticoid receptor in vulnerability to stress-induced depression by performing comprehensive behavioral studies. - We will then evaluate the impact of the glucocorticoid receptor on mitochondrial function and structure. Lastly, we will apply a pharmacological approach aiming to mitigate stress-induced depression caused by physiological changes given by the - glucocorticoid receptor. This will lead to the understanding of the contribution of the glucocorticoid receptor in the nucleus accumbens to define vulnerability and resilience to develop stress-induced depression, and might lead to novel therapeutics - for counteracting stress-induced depression. - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - MitoDyaD - - - H2020-MSCA-IF-2016 - - - 748051 - - - - - ABERYSTWYTH UNIVERSITY - - - EUR 183 454,80 - - - Reflexivity as capacity in EU’s border security: a contribution to theory and practice through the case of Polish Border Guard training - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Lived experience of border guards receives surprisingly little attention given the current challenges of European border security and its humanitarian aspects. The proposal sets out a plan to redress this hiatus through - conducting an important policy-relevant research project that encourages reflexivity as capacity in border guard training. As a follow-up from my previous research in European security and preliminary results from studying assistance to border - reform, it aims to both aid the EU’s efforts to establish a more efficient European Border and Coast Guard and foster greater humanitarian and democratic sensibilities in European border policy. In contrast to existing approaches which neglect - reflective practice of actors on the ground, the project explores new empirical evidence, hones new theoretical avenues and develops participative dissemination techniques to nurture reflexivity in cooperation between scholars and practitioners. In - order to do so, it studies the lived experience of Polish Border Guard (PBG) officers involved in the transformation of their service in the aftermath of EU enlargement which occurred at the intersection of receiving training from Western European - border guards and providing training assistance to the Ukrainian Border Guard service. This unique situation of dual interaction triggers reflection and creates conditions for knowledge production that the project taps into. The core of the project - consists in fieldwork with participants to study, make use of for participative design and inspire interpretations of shifting training methods towards installing greater reflexivity. The latter is planned as an innovative dissemination technique - developed through the researcher’s training in action research and reflective teaching practice at Aberystwyth University and tested in secondment with a local border guard facility to contribute to a more context-informed EU border security policy. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - RefBORDER - - - H2020-MSCA-IF-2016 - - - 749314 - - - - - UNIVERSITAET REGENSBURG - - - EUR 171 460,80 - - - Baryons in extreme QCD matter - - - EUR 171 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - Quantum Chromodynamics (QCD) undergoes a crossover from the hadronic phase at low temperatures T to a quark-gluon plasma (QGP) phase at high T. This crossover and properties of the QGP phase are important for understanding the - evolution of the early universe and are being studied by major Heavy Ion Collision (HIC) experiments at RHIC and LHC. The transition temperature and many QGP properties have been determined by Lattice QCD simulations. However, connecting these to - experimental remnants of QGP fireballs produced at HICs is not straightforward. Thermal effects will modify the properties of the excitations (mesons and baryons) within the medium. We propose to investigate these in-medium changes using lattice QCD - methods, shedding light onto the dynamics of HIC fireballs. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - XQCDBaryons - - - H2020-MSCA-IF-2016 - - - 744659 - - - - - THE UNIVERSITY OF BIRMINGHAM - - - EUR 195 454,80 - - - Enzyme-Degradable Polyion-Complex (PIC) Particles for the Treatment and Detection of Pseudomonas aeruginosa - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Here, we will develop new enzyme-degradable polymers for the preparation of polyion complex (PIC) particles based of antimicrobial molecules with low charge densities. The main goals are: - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - AntibioPICs - - - H2020-MSCA-IF-2016 - - - 747801 - - - - - CARL VON OSSIETZKY UNIVERSITAET OLDENBURG - - - EUR 171 460,80 - - - Test, Predict, and Improve Musical Scene Perception of Hearing-Impaired Listeners - - - EUR 171 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - In both speech and music perception, the auditory system decomposes sounds that overlap in time and frequency into distinct perceptual events and streams, which is referred to as auditory scene analysis (ASA). Hearing-impaired - listeners suffer from severely compromised ASA, as illustrated by their immense difficulties to understand speech in noisy environments. Although the central role of ASA in shaping the experience of music is widely acknowledged—perceptually - organizing sounds from multiple instruments or voices into melody and accompaniment, for instance—the role of hearing loss in musical scene perception remains largely unexplored. At the same time, hearing aids are typically designed for speech - perception, not for music perception. Adopting a transdisciplinary approach that employs methods from music perception, auditory modelling, and signal processing, this Marie Skłodowska-Curie Action aims to Test, Predict, and Improve Musical Scene - Perception of Hearing-Impaired Listeners (TIMPANI). Firstly, a series of music perception tasks will be designed to assess the effects of hearing loss on musical scene perception abilities. Secondly, an auditory model will be developed in order to - predict normal and hearing-impaired listeners’ performance in ASA tasks. Finally, algorithms for scene-aware music mixing will be developed for improved music perception of hearing aid users. This research is timely and addresses the H2020 challenges - to improve demographic change and wellbeing in European societies: The rise of hearing loss calls for scientific and technological breakthroughs in order to include hearing-impaired individuals in the cultural resource of music listening and making. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Germany - - - TIMPANI - - - H2020-MSCA-IF-2016 - - - 747124 - - - - - UNIVERSITY OF LEEDS - - - EUR 251 857,80 - - - Superconducting Spintronics for Highly Energery Efficient Cryogenic Memory Applications - - - EUR 251 857,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The dissipation of heat in traditional silicon (CMOS) based electronics is a major source of inefficiency and environmental impact. Superconductors are, by nature, dissipationless. Computing via logic circuits based on - Josephson junctions is also faster, but the largest remaining problem is the lagging development of low-temperature memory. To achieve the promised efficiency increases of these computers requires a new type of low-temperature memory architecture. - - 2020-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - SUPERSPIN - - - H2020-MSCA-IF-2016 - - - 743791 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 170 121,60 - - - Generating yeast biodiversity by mitochondrial introgression for wine innovation - - - EUR 170 121,60 - - - Spain - - - Research Organisations - - Wine global demand is decreasing due to a shift in consumer preferences and cultural changes. The EU is a GLOBAL LEADER in WINE production, whose wine companies wants to decrease ethanol content, while improving organoleptic - properties to deal with these new demands. YEASTS, mainly Saccharomyces cerevisiae, play a KEY ROLE during wine fermentation, when alcohol and the main flavors are produced. Application of new yeasts, produced by genetic engineering, is limited due - to the non-acceptance of Genetically Modified Organisms (GMOs). We PROPOSE to apply non-GMO methodologies, to obtain IMPROVED YEASTS by the generation of yeast strains (cybrids), with mitochondrial genomes (mitogression) from non-cerevisiae species, - or hybrids, increasing yeast DIVERSITY, to select strains whose fermentation products match wine company expectations. We will ANSWER some BASIC research QUESTIONS: how is genotype molded by the presence of a foreign mitochondrial genome? Are these - changes common between independent experiments and wild isolates? And, are evolved strains starting to show evidence of speciation from their ancestors? The results of this project will IMPACT the WINE INDUSTRY by generating new potential commercial - strains, and future collaborations. The knowledge gained through this proposal will demonstrate to the scientific community the use of novel methodologies as well as expose the general public to the importance of biodiversity for industrial processes - and how the transfer of genetic material and experimental evolution can produce beneficial traits for our societies. The researcher (evolutionary biology and bioinformatics background), supervisor (microbiology, systems biology, and synthetic biology - background), and host institution (facilities, knowledge, experience, and supporting elements) will form a perfect entity for the development of MITOGRESSION proposal, and to CONSOLIDATE the scientific career of the researcher for his future - INDEPENDENT position. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Spain - - - Mitogression - - - H2020-MSCA-IF-2016 - - - 747775 - - - - - UNIVERSITAT WIEN - - - EUR 166 156,80 - - - Federal state against cities: Immigrant incorporation in the context of new immigrant reception - - - EUR 166 156,80 - - - Austria - - - Higher or Secondary Education Establishments - - The unprecedented number of newcomers in the past year provides an immense challenge to federal state and local authorities, who have to co-ordinate the provision of policies and funds for incorporating immigrants into - society. This comparative study seeks to understand the role of federal states for the incorporation of immigrants in the context of the recent influx of asylum seekers in Germany and Austria in 2015. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Austria - - - FEDCIT - - - H2020-MSCA-IF-2016 - - - 740447 - - - - - KOC UNIVERSITY - - - EUR 152 988 - - - Critical Slope Gross-Zagier formula and Perrin-Riou's Conjecture - - - EUR 152 988 - - - Turkey - - - Higher or Secondary Education Establishments - - The main objective of this project is to prove a p-adic Gross-Zagier formula for the critical slope p-adic L-functions attached to p-ordinary modular forms. As we will explain in the main body of this proposal, such a formula - will lead, among other things, to a full proof of a conjecture of Perrin-Riou (that gives a precise comparison between p-adic Beilinson-Kato elements and Heegner points). - - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Turkey - - - CriticalGZ - - - H2020-MSCA-IF-2016 - - - 745691 - - - - - UNIVERSITAT DE LES ILLES BALEARS - - - EUR 170 121,60 - - - Simulating REalistic HIgh-resolution PREcipitation in the tropics - - - EUR 170 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - Changes in rainfall characteristics over the Maritime Continent affect a rapidly increasing population of 275 million people through effects on agriculture, forest fires, floods and vector-borne diseases. However, current - atmospheric models fail to represent most features of precipitation in the region, such as its distinctive strong diurnal cycle. Therefore, our knowledge of the physical processes initiating and propagating convective systems that generate - precipitation in the Maritime Continent is very limited. In addition, the Maritime Continent is at a centre of interactions across scales, hence global model errors in this region propagate through the entire earth system and affect model estimates - in remote regions too. This project is aimed at exploring our ability to simulate realistic precipitation by incorporating explicit convection and fine-scale ocean-atmosphere interactions in regional models. We will quantify the interplay between sea - breeze circulation, ocean-atmosphere processes and convective systems to produce precipitation in the Maritime Continent and how it could change in the future. As such, this project will also advance our understanding of sea breeze and convective - processes that are of major importance to a breadth of locations globally. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Spain - - - REHIPRE - - - H2020-MSCA-IF-2016 - - - 743547 - - - - - SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI DI TRIESTE - SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI DI TRIESTE - - - EUR 150 000 - - - Neuromicronica: Modular behavioural neuroscience - - - EUR 150 000 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Neurological disorders, particularly dementia, constitute arguably the greatest socioeconomic challenge to the aging European continent. There is growing realization that rodents can serve as models not just for basic - neurobiological processes (e.g. synaptic transmission) but also for remarkably complex, primate-like and even human-like cognitive operations such as perception, memory, economics, social interaction, and decision making. Better rodent models for - cognition are necessary to test theories on the molecular basis of neurological disorders and to test therapies: only through rodent behavioral neuroscience can the circuits that give rise to cognitive operations be examined and dissected, probed and - manipulated. The aim of ERC Advanced Project ‘CONCEPT’ is to understand the neuronal bases of perception, memory and decision making. To achieve this aim, we have developed innovative instrumentation incorporating the following elements: (i) awake - rodent interacting with its environment, (ii) precisely controlled sensory stimuli, (iii) imaging of animal’s action, (iv) electrophysiology with moveable microelectrode arrays, (v) optogenetics, (vi) integration and management of all incoming and - outgoing signals. Here, we present our plan for bringing these instruments to a stage where they can constitute the initial product line for a spin-off named NeuroMicronica. The community’s interest in NeuroMicronica is already testified by the - commercialization of the electrode drive in agreement with a prestigious USA company, by NeuroMicronica’s selection in a technology startup competition, and by the enthusiastic and constructive feedback from collaborators now employing beta versions. - The expected outcome of NeuroMicronica will be to make this lab’s longstanding experience in instrumentation available to the community, allowing investigators to better exploit rodent behavioral neuroscience as a model for normal and pathological - human cognition. - - 2018-09-30, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Italy - - - NEUROMICRONICA - - - ERC-2016-PoC - - - 737609 - - - - - HERIOT-WATT UNIVERSITY - HERIOT-WATT UNIVERSITY - - - EUR 1 999 135 - - - Two-dimensional quantum photonics - - - EUR 1 999 135 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Quantum optics, the study of how discrete packets of light (photons) and matter interact, has led to the development of remarkable new technologies which exploit the bizarre properties of quantum mechanics. These quantum - technologies are primed to revolutionize the fields of communication, information processing, and metrology in the coming years. Similar to contemporary technologies, the future quantum machinery will likely consist of a semiconductor platform to - create and process the quantum information. However, to date the demanding requirements on a quantum photonic platform have yet to be satisfied with conventional bulk (three-dimensional) semiconductors. - - 2022-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - 2DQP - - - ERC-2016-COG - - - 725920 - - - - - UNIVERSITE DE GENEVE - - - EUR 187 419,60 - - - Deep brain targets for neurostimulation in affective disorders - - - EUR 187 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - Objective: The overarching goal of proposed project is to provide necessary knowledge about neurobiology of Major Depression Disorder (MDD), which would lead to higher efficacy in treatment of this affective disorder. The - research objectives of the action are 1) identification of electrophysiological biomarkers of functional brain abnormities in treatment resistant depression (TRD) and 2) suggestion of novel targets for neurostimulation in patients with TRD. - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - Debrasa - - - H2020-MSCA-IF-2016 - - - 739939 - - - - - KUNGLIGA TEKNISKA HOEGSKOLAN - - - EUR 173 857,20 - - - Theoretical prediction of spectral biomarkers for Alzheimer's disease enabled by highly efficient and adaptable mutli-level response methods - - - EUR 173 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - Luminescent conjugated oligothiophenes are highly promising candidates for biomarkers for amyloid misfolds and thereby for early-stage detection of neurodegenerative diseases such as Alzheimer’s and Parkinson's disease. The - elucidation of the microscopic mechanism and design principles behind these biomarkers requires theoretical assistance. Finding suitable theoretical models that allow sufficiently accurate spectra calculations for such large, dynamic, and complex - biomolecular systems is a highly challenging task: In practice, it is currently neither possible to include all possible factors, nor to rigorously test their importance for the actual simulation. There is, hence, a great need for efficient and - adaptive theoretical models capable of incorporating the essential factors in spectra calculation of biomolecular systems sufficiently accurately. - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - FreezeAlz - - - H2020-MSCA-IF-2016 - - - 745906 - - - - - VIB - VIB - - - EUR 150 000 - - - A comparative clinical study of a stool-based versus a blood-based screening test for earlydetection of CRC - - - EUR 150 000 - - - Belgium - Belgium - - - Research Organisations - Research Organisations - - Colorectal cancer (CRC) is the third most common cancer worldwide and the second leading cause of cancer deaths in Europe and USA. Its incidence and difficult early-diagnosis make CRC a primary focus in the oncology community. - Although colonoscopy is currently the most reliable clinical tool for precise detection of CRC, the invasive nature and the incurred cost have hampered the wide application of this procedure. On the other hand, the fecal occult blood test (FOBT) and - the fecal immunoistochemical test (FIT) are non-invasive screening tests that can be used prior to colonoscopy. However, they both lack the sensitivity or specificity required for an effective screening tool and they require meticulous dietary - restriction, overall not reaching the full compliance of the general population. Thus, there is a pressing need to identify specific non-invasive biomarkers for early diagnosis of CRC. Within the frame of the ERC starting grant OxyMO, we investigated - the diagnostic potential of blood derived circulating monocytes for colorectal cancer (CRC). Our transcriptome characterization revealed a CRC-specific gene signature that was further developed as the ‘Monomark‘ diagnostic test (patent - WO2013/110817), which showed a strong diagnostic power for CRC detection. This signature was triggered by signals specifically released by CRC cells regardless of their stromal niche (primary tumor vs. metastatic site) or oxygen tension. In this - prospective study, we will compare the strength of the Monomark signature towards the FIT test in patients with a positive stool test. Therefore, in parallel to the routine FIT screening, blood samples will be harvested and the monocyte genetic - profile will be determined. This fundamental study, will disclose the diagnostic power of our biomarker panel head to head with the well-established FIT diagnostic test, a core prerequisite for the commercialization of the Monomark test as an - alternative and more reliable CRC screening tool. - - 2018-09-30, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Belgium - - - Monomark - - - ERC-2016-PoC - - - 737596 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 1 981 721 - - - Hybrid Indium Phosphide on Silicon nanophotonics for ultimate laser diodes, flip-flops and memories - - - EUR 1 981 721 - - - France - France - - - Research Organisations - Research Organisations - - The HYPNOTIC project aims at achieving a breakthrough in Silicon laser science and technology by taking forward the III-V semiconductors on Silicon hybrid technology into the nanophotonic world to make the dream of the - convergence of microelectronics and photonics on a chip come true. This project intends to take up the challenge of bringing to reality electrically powered photonic crystal nanolasers as reference sources for dense integration and logical processing - in a Silicon-based optical platform by accomplishing: (i) power efficiency with extremely low activation energies of few fJ, (ii) high bandwidth beyond 40Gbits/s, (iii) compactness with footprints less than 100µm² for high integration density of - 103-104 of devices per mm2. - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - France - - - HYPNOTIC - - - ERC-2016-COG - - - 726420 - - - - - UNIVERSITAET HAMBURG - UNIVERSITAET HAMBURG - - - EUR 1 923 190 - - - Slow motion: Transformations of musical time in perception and performance - - - EUR 1 923 190 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Slow motion is widely employed in popular media such as emotional movie scenes or in the broad-casting of momentous bodily and physical actions. Slow motion functions as a counterpoint to the perceived acceleration of life, - and non-profit organisations and meditation practices promote its virtues. Slow motion is used as a beneficial rehearsal strategy in music, dance, and other movement-based arts and sports. This research proposal shifts existing boundaries by - hypothesizing that the time-stretching mechanism of slow motion is a) associated with high emotional significance, b) beneficial for interpersonal coordination, c) relevant in cross-modal approaches with augmented feedback such as the sonification of - human movements, d) reduces cognitive working memory load in learning. It is assumed that music as a temporal-motional art is central for the study of these processes, since music consists of structured time at different hierarchical levels and - deeply “moves” people. The musical surface structure (on a note-to-note level) allows synchronisations at higher tempi compared to deeper structural levels (such as strong beats in a measure or phrases). Music may thus transform perceptions of motion - and time. The proposed project contains three main phases, first addressing the perception of slow motion in music and dance in relation to the attentional, emotional and aesthetic effects on the audience. In the second phase, performance qualities - are studied, addressing cognitive load, imagery, and interpersonal coordination at slow tempi. High-speed cameras, a 3D motion capture system and physiological measures are used to analyse the psychological and bodily processes involved. The final - phase aims at the creation of three applications, including a learning app for portable devices, a film with super slow motion sequences based on the studies, and sonifications of Tai Chi movements. These applications present the aesthetic dimensions - of slow motion to a wider audience. - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - SloMo - - - ERC-2016-COG - - - 725319 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - Eidgenössische Technische Hochschule Zürich - - - EUR 1 505 000 - - - MULtiple PROperties Single Molecule Magnets - - - EUR 1 505 000 - - - France - France - Switzerland - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - - The goal of the MULTIPROSMM project is to design systems able to present magnetic bistabilities under different stimuli (temperature, magnetic field or light) on an unprecedented large temperature range, i.e. very low - temperature with Single Molecule Magnet (SMM) behaviour, intermediate temperature with Light Induced Excited State Trapping (LIESST) and high temperature with SpinCrossOver (SCO). On one hand, as a photography of the energy-splitting of the - spectroscopic states, the lanthanide luminescence will be used as a key tool for the understanding of the magnetic properties of lanthanide ions. On the other hand, Circularly Polarized Luminescence (CPL) combines the sensitivity of the luminescence - with crucial information on the chiral environment. A step by step synthetic strategy will be used to elaborate molecular systems in which the coexistence of i) SMM and SCO; ii) SMM and CPL and iii) SMM, SCO and CPL are operating. The enhancement of - the magnetic properties is needed to step forward towards applications. To reach such optimizations, the quantum regime of the SMM and the internal magnetic field must be vanished playing with the hyperfine coupling and magnetic dilutions. Both - isotopic enrichment and shaping (i.e. decoration of both mesoporous silica and nanoparticle surfaces) of the designed systems could allow high magnetic performance in multiple properties SMM. The final result could be a system suitable for very high - density data storage on a wide temperature range (from cryogenic to room temperature). - - 2022-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - France - - - MULTIPROSMM - - - ERC-2016-COG - - - 725184 - - - - - POLITECNICO DI MILANO - POLITECNICO DI MILANO - - - EUR 1 999 194 - - - MIcrobiota-Gut-BraiN EngineeRed platform to eVAluate intestinal microflora impact on brain functionality - - - EUR 1 999 194 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - What is the relation between the intestinal microflora and the brain in the development of neurodegenerative disorders like Alzheimer's and Parkinson's disease? - - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Italy - - - MINERVA - - - ERC-2016-COG - - - 724734 - - - - - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - - - EUR 1 998 971 - - - Uranium isotope fractionation: a novel biosignature to identify microbial metabolism on early Earth - - - EUR 1 998 971 - - - Switzerland - Switzerland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Prokaryotes (archaea and bacteria) are the most abundant form of life both at present and throughout paleohistory and exhibit exquisite metabolic diversity, unmatched by eukaryotes. On early Earth, the absence of atmospheric - oxygen led to the emergence of anaerobic microbial metabolisms such as methanogenesis, sulfate reduction, iron reduction, and denitrification. Non-isotope and isotope tools used to study ancient microbial life have provided evidence for each of these - types of metabolisms in the rock record. However, there remains much uncertainty and debate regarding this evidence, primarily because of confounding effects of abiotic processes, and ambiguity in interpretation of isotopic signatures. - - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Switzerland - - - UNEARTH - - - ERC-2016-COG - - - 725675 - - - - - JOHANNES GUTENBERG-UNIVERSITAT MAINZ - JOHANNES GUTENBERG-UNIVERSITAT MAINZ - - - EUR 2 000 000 - - - Novel structures in scattering amplitudes - - - EUR 2 000 000 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This project focuses on developing quantum field theory methods and applying them to the phenomenology of elementary particles. At the Large Hadron Collider (LHC) our current best theoretical understanding of particle physics - is being tested against experiment by measuring e.g. properties of the recently discovered Higgs boson. With run two of the LHC, currently underway, the experimental accuracy will further increase. Theoretical predictions matching the latter are - urgently needed. Obtaining these requires extremely difficult calculations of scattering amplitudes and cross sections in quantum field theory, including calculations to correctly describe large contributions due to long-distance physics in the - latter. Major obstacles in such computations are the large number of Feynman diagrams that are difficult to handle, even with the help of modern computers, and the computation of Feynman loop integrals. To address these issues, we will develop - innovative methods that are inspired by new structures found in supersymmetric field theories. We will extend the scope of the differential equations method for computing Feynman integrals, and apply it to scattering processes that are needed for - phenomenology, but too complicated to analyze using current methods. Our results will help measure fundamental parameters of Nature, such as, for example, couplings of the Higgs boson, with unprecedented precision. Moreover, by accurately predicting - backgrounds from known physics, our results will also be invaluable for searches of new particles. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - AMPLITUDES - - - ERC-2016-COG - - - 725110 - - - - - UNIVERSITAET PADERBORN - UNIVERSITAET PADERBORN - - - EUR 1 963 750 - - - Quantum Particles on Programmable Complex Reconfigurable Networks - - - EUR 1 963 750 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Understanding the complex interactions and dynamics of multiple quantum particles within large networks is an extremely challenging task, but doing so reveals the underlying structure of an enormously diverse range of - phenomena. Therefore, a reliable platform to investigate complex quantum network dynamics, which incorporates the rich interplay between noise, coherence and nonclassical correlations, will be an extremely powerful tool. - - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - QuPoPCoRN - - - ERC-2016-COG - - - 725366 - - - - - UNIVERSITY COLLEGE LONDON - UNIVERSITY COLLEGE LONDON - - - EUR 1 358 925 - - - Birational Geometry, B-branes and Artin Stacks - - - EUR 1 358 925 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Derived categories of coherent sheaves on a variety are a fundamental tool in algebraic geometry. They also arise in String Theory, as the category of B-branes in a quantum field theory whose target space is the variety. This - connection to physics has been extraordinarily fruitful, providing deep insights and conjectures. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - BG-BB-AS - - - ERC-2016-COG - - - 725010 - - - - - UNIVERSITAET BREMEN - UNIVERSITAET INNSBRUCK - CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - CONTROL Y PROSPECCIONES IGEOTEST SL - INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER - ISTITUTO NAZIONALE DI OCEANOGRAFIA E DI GEOFISICA SPERIMENTALE - CONSIGLIO NAZIONALE DELLE RICERCHE - STIFTELSEN NORGES GEOTEKNISKE INSTITUTT - NATURAL ENVIRONMENT RESEARCH COUNCIL - UNIVERSITY OF DURHAM - - - EUR 3 894 543,36 - - - Submarine LAndslides and Their impact on European continental margins - - - EUR 3 894 543,36 - - - Germany - Austria - Germany - Spain - Spain - France - Italy - Italy - Norway - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - - The over-arching aim of the SLATE ETN is (i) to understand key factors triggering submarine landslides, the subsequent motion and evolution of failed material, and ensuing geohazards eg tsunamis and (ii) to integrate an - innovative broad range of scientific disciplines and private sector needs into a novel training and co-supervision of 15 ESRs. - - - 2021-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - SLATE - - - H2020-MSCA-ITN-2016 - - - 721403 - - - - - ALBERT-LUDWIGS-UNIVERSITAET FREIBURG - ALBERT-LUDWIGS-UNIVERSITAET FREIBURG - - - EUR 1 982 938 - - - Towards the ultimate dark matter detector - - - EUR 1 982 938 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Dark matter is a major component of the Universe, outnumbering ordinary baryonic matter by a factor 5. As it has not yet been observed, its detection and subsequent characterization is one of the most important goals in - particle physics. ULTIMATE will be the first project world-wide that focuses entirely on cutting-edge research towards the ultimate detector. Using a low-background time projection chamber (TPC) filled with ~40t of liquid xenon (LXe), this instrument - will search for Galactic dark matter in the form of Weakly Interacting Massive Particles (WIMPs). It will probe the entire experimentally accessible parameter space above masses of a few GeV/c², which is eventually limited by irreducible neutrino - backgrounds. If dark matter will be detected by the next-generation experiments, the ultimate detector will deliver a high statistics WIMP sample to study its properties. - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - ULTIMATE - - - ERC-2016-COG - - - 724320 - - - - - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - - - EUR 2 091 338 - - - Protection of cardiometabolic inflammation by modulation of myeloid glutamine homeostasis - - - EUR 2 091 338 - - - France - France - - - Research Organisations - Research Organisations - - The metabolic syndrome (MetS) represents one of the major public health challenges worldwide. It reflects a combination of medical disorders that, when occurring together, increase the risk of developing diabetes and - cardiovascular disease. The prevalence in the USA is estimated at 30% of the population and the European community follows this trajectory. It is now recognized that the state of chronic low-grade inflammation may favor the onset and progression of - the MetS. While the notion of metabolic flexibility in hematopoietic cells has recently emerged in several inflammatory diseases, the origin of this immunometabolic alteration in the MetS remains elusive. There is a growing appreciation that the - apportioning of nutrients into different metabolic pathways can support or direct functional immune and hematopoietic changes. Glutamine is the most abundant amino acid in the plasma and an important energy source through glutaminolysis. Despite its - potential proliferative and/or immunosuppressive function and the strong association between high glutamine-to-glutamate ratio with cardiometabolic traits, the underlying mechanisms are poorly understood. Thus, there is a considerable therapeutic - interest in better understanding the mechanisms linking glutamine to cardiometabolic risks and in particular cardiometabolic inflammation. In PROGLUTASIS, we will investigate the metabolic and immune regulation of glutamine homeostasis in the - metabolic syndrome. We will validate the contribution of glutaminolysis in cardiometabolic inflammation, including obesity, diabetes and atherosclerosis through its role on hematopoiesis and macrophage dynamics. Given the ubiquitous association - between glutamine and chronic metabolic stress, we expect that identifying the underlying molecular mechanism will offer novel therapeutic perspective on how to intervene in this pathway. This will ultimately allow for tailored strategies aimed at - dampening cardiometabolic inflammation in the MetS. - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - France - - - PROGLUTASIS - - - ERC-2016-COG - - - 724838 - - - - - UNIVERSITEIT UTRECHT - UNIVERSITEIT UTRECHT - - - EUR 1 499 082 - - - ‘This country is ours’: Collective psychological OWNERShip and ethnic attitudes - - - EUR 1 499 082 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Even in the absence of legal ownership, people tend to experience objects, places, and ideas as belonging to them (‘mine’). This state of mind is called psychological ownership. Research has shown that experiences of ownership - are very important for individuals, but can also lead to interpersonal conflicts. What we know almost nothing about is collective psychological ownership (CPO): a shared sense that something is ‘ours’. CPO might be especially relevant with regard to - territories and in the context of intergroup relations. Statements like ‘we were here first’ or ‘we built this country’ are increasingly used by right-wing politicians in immigration countries to claim ownership on historical basis for the dominant - ethnic group, and to exclude newcomers. There are also contexts where two established groups disagree about territorial ownership, such as Albanians and Serbs in Kosovo. - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - OWNERS - - - ERC-2016-STG - - - 715842 - - - - - UNIVERSITEIT UTRECHT - UNIVERSITEIT UTRECHT - - - EUR 2 496 611 - - - BiogENesis and Degradation of Endoplasmic Reticulum proteins - - - EUR 2 496 611 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The Endoplasmic Reticulum (ER) membrane in all eukaryotic cells has an intricate protein network that facilitates protein biogene-sis and homeostasis. The molecular complexity and sophisticated regulation of this machinery - favours study-ing it in its native microenvironment by novel approaches. Cryo-electron tomography (CET) allows 3D im-aging of membrane-associated complexes in their native surrounding. Computational analysis of many sub-tomograms depicting the same - type of macromolecule, a technology I pioneered, provides subnanometer resolution insights into different conformations of native complexes. - - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - BENDER - - - ERC-2016-COG - - - 724425 - - - - - HERIOT-WATT UNIVERSITY - HERIOT-WATT UNIVERSITY - - - EUR 1 499 985 - - - Deaf mobilities across international borders: Visualising intersectionality and translanguaging - - - EUR 1 499 985 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Deaf signers’ international mobilities are rapidly increasing. These mobilities are unique in a number of respects: while being biologically deaf leads to certain limitations and to discrimination and inequalities, being - skilled in visual language also creates possibilities and opportunities for communication across national and linguistic borders. There are two main research questions in the project. First, within contexts of international deaf spaces, how does the - status of being deaf intersect with other statuses, particularly ethnicity, nationality, education, religion and gender, and which meaningful connections or accumulated inequalities occur? Second, how do deaf signers in these contexts practice and - experience translanguaging, by making strategical use of multiple languages and language modalities, and International Sign? Four subprojects will focus on structurally different kinds of international deaf mobilities: (1) forced migration, (2) - labour migration, (3) professional mobility, and (4) tourist mobility. The research team will be all-deaf as to maximise access to various sign languages, access to distinct deaf networks, and insights into deaf ways of living. This is a unique - endeavour as most deaf-related research is hearing-led. The methodology will be ethnographic but neither logocentric nor audiocentric as visual methods (photography, video, mapping, and the production of four ethnographic documentaries) will be - heavily employed, doing justice to the visual nature of sign language communication. By scrutinizing and bridging the concepts of intersectionality and translanguaging, this study will contribute to the study of growing complexity in diversity and - mobility; the production/delimitation of social spaces particularly through language practices, strategies and ideologies; while engaging with issues of researchers’ embodiment, positionality and engagement, concerns which are central to the - so-called third wave in deaf studies. - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - MobileDeaf - - - ERC-2016-STG - - - 714615 - - - - - CONSIGLIO NAZIONALE DELLE RICERCHE - - - EUR 244 269 - - - On the route of multiculturalism(s). Marking and hybridizing identities in the late 17th and early 18th centuries Mediterranean port cities - - - EUR 244 269 - - - Italy - - - Research Organisations - - This project aims to analyze the phenomenon of multiculturalism in four Mediterranean port cities of the late seventeenth and the early eighteenth centuries. The research uses three identity markers (foodways, clothing, and - language) to chart how differences in the political and physical environments affect the balance between marking and hybridizing identities in the port cities of Izmir, La Valletta, Livorno and Marseille. Although very different amongst themselves, - these four cities, placed on a maritime trading route cutting the Mediterranean from east to west, share a highly developed cultural, ethnical, and religious pluralism. The comparative analysis adopted will shed light on the concept of - multiculturalism(s) in the pre-modern Euro-Mediterranean space, explaining how members of the same group handled coexistence following different strategies. In analyzing identity as a dynamic process, the research enters into the historiographical - debate on the One-Plural nature of the Mediterranean on two critical levels: the ways in which Mediterranean identities interact with one another and how they generate a multicultural zone. Through an interdisciplinary study, the project will shape - the ineradicable ambiguous nature of multicultural zones in the Mediterranean. This goal will be undertaken through the analysis and verification of three main assumptions that form the basis of the research: - - 2020-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Italy - - - MedRoute - - - H2020-MSCA-IF-2016 - - - 747030 - - - - - UNIVERSITA DEGLI STUDI DI PADOVA - UNIVERSITA DEGLI STUDI DI PADOVA - - - EUR 1 498 232 - - - Dissecting the crosstalk between metabolism and transcriptional regulation in pluripotent stem cells. - - - EUR 1 498 232 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Pluripotent Stem cells (PSCs) can give rise to all differentiated cells of the body and the germ line, which makes them conceptually fascinating and a valuable tool for regenerative medicine. Mouse PSCs are devoid of any - developmental restriction partly thanks to their “open” chromatin, characterised by remarkably low levels of repressive epigenetic modifications. Metabolism is a key feature that can be adjusted to meet the cell’s needs, and that has the potential to - feedback on transcription and epigenetics. How metabolism is regulated in PSCs and whether this is important for their biology remains largely unknown. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Italy - - - MetEpiStem - - - ERC-2016-STG - - - 716910 - - - - - KOBENHAVNS UNIVERSITET - - - EUR 212 194,80 - - - The International Criminal Court and the Judicial Function: a Socio-Legal Study of Judicial Perceptions and Practices - - - EUR 212 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - INCRICO investigates the ways in which the International Criminal Court (ICC) perceives its judicial function and how this impacts its legal practices. The overall goal is to offer a realistic account of the international - criminal judiciary with regard to judicial deliberations, reasoning and drafting judgments. To meet this objective, INCRICO aims to tackle the topic using a unique interdisciplinary approach, employing doctrinal legal analysis as well as contemporary - sociology of law for explaining international criminal law and international criminal courts and their link to global society. The project’s specific objectives are to: (1) gather, analyse and collate international legal data and sources relevant for - determining the content, scope, nature and practice of the ICC’s judicial function, as well as the relevant body of the ICC’s case law/jurisprudence/applicable law, including dissenting and individual/separate opinions; (2) gather (through in-depth - interviews with the ICC's judges) and analyse qualitative data on the judges’ perceptions and understanding of their judicial function, in terms of what and how the judges really think, and what they are doing and why, so as to identify the judges’ - view and experience at the ICC and how this correlated to the case law of the Court; (3) integrate legal assessment of dissents/case law/jurisprudence of the ICC with the judges’ accounts to map out and critically analyse the ICC’s judicial function; - (4) increase awareness and knowledge of the ICC’s judicial function among relevant scientific and criminal justice management/policy making communities, and the general public. INCRICO is involving an excellent academic and interdisciplinary - environment at iCourts where the researcher will spend the entire period. This is a unique proposal which targets growing concerns on legitimacy, effectiveness, independence and fairness of global criminal judiciary. Thus, it fits perfectly with the - goals of the IF and Horizon 2020. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - Denmark - - - INCRICO - - - H2020-MSCA-IF-2016 - - - 746768 - - - - - LUNDS UNIVERSITET - - - EUR 173 857,20 - - - Supercritical carbon dioxide for delipidation of soft tissue - Suppressing transplant rejection. - - - EUR 173 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - The lack of donor organs and tissue constitutes a health and social problem. In 2014 about 119.873 organs were transplanted, that is less than the 10% of global needs. Critical patients do not survive the waiting time while - transplanted people must receive lifelong immunosuppressive therapy with severe side effects. Also, there is a risk to lose the new organ to chronic rejection, which is linked to the presence of cellular components e.g. glycolipids and lipoproteins - in the donor tissue. There is currently no process to remove lipids and lipid antigens from soft tissue prior transplantation. - - 2019-05-21, ongoing project - - - 2017-05-22 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - CriTiClean - - - H2020-MSCA-IF-2016 - - - 746137 - - - - - Institute of Science and Technology Austria - Institute of Science and Technology Austria - - - EUR 1 984 922 - - - Cellular navigation along spatial gradients - - - EUR 1 984 922 - - - Austria - Austria - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Gradients of extracellular signalling molecules are a central concept in biology: for example gradients of guidance-cues such as chemokines position migrating cells in development, malignancy and immunity. Because immune cells - are permanently motile, their function most critically depends on spatiotemporal orchestration by a large family of chemokines. To specify direction, concentration differences of the chemokine need to be interpreted by the migrating cell. Most - mechanistic knowledge about eukaryotic gradient sensing is inferred from the amoeba Dictyostelium discoideum migrating towards soluble gradients of cyclicAMP. The biology of chemokines is much more diverse, e.g. gradients can take different shapes - and, importantly, they do not only emerge in the soluble but also in the immobilized phase. In this proposal we suggest to address the principles of leukocyte chemotaxis using convergent system wide, cell biological and intravital approaches. - Employing a newly developed, genetically tractable primary leukocyte system, we will test the contribution of spatial and temporal signalling paradigms of gradient sensing. Quantitative microscopy will be used to image cellular responses to - engineered immobilized and soluble chemokine gradients of defined shape as well as to optogenetically triggered signals. In a complementary approach we will screen for proteins responding to chemokine signalling and perform the first genome wide - genome editing-based loss of function screen for directionally persistent chemotaxis and haptotaxis. Findings will be validated in vivo to guarantee physiological relevance. In a support project we will precision-engineer the genome of primary - leukocytes suitable for assaying migration. A unique combination of cellular, genetic, engineering and quantitative microscopy tools will allow this new and holistic approach to a question which is not only fundamental for immunology but also for - understanding development and cancer biology. - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Austria - - - GRADIENTSENSING - - - ERC-2016-COG - - - 724373 - - - - - KOBENHAVNS UNIVERSITET - BROWN UNIVERSITY - - - EUR 260 227,80 - - - Local Diversity and Long-Run Development - - - EUR 260 227,80 - - - Denmark - United States - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Social scientists have long studied the effects of population diversity on society. The research project proposed here breaks new ground in multiple dimensions by rigorously estimating the long-run effects of (i) local - population diversity, (ii) individual diversity, and (iii) the interaction between these two concepts, on comparative socioeconomic performance across locations and lineages within a country. - - 2020-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Denmark - - - LODALORD - - - H2020-MSCA-IF-2016 - - - 753615 - - - - - UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN - - - EUR 187 866 - - - Human Rights, Memorialization and Nationalism - - - EUR 187 866 - - - Ireland - - - Higher or Secondary Education Establishments - - This research deals with the rise of memorialization standards and policy-oriented attempts to engage transitional societies to develop and adopt specific normative forms of remembrance. This project addresses one particular - human rights assumption - that the standardization of memory enforced through memorialization policies is effective and necessary in promoting human rights values. Human rights advocates insist on memorialization as a crucial step in establishing - moral responsibility for past atrocities understanding it as an insurance policy against the repetition of crimes. In nationalist ideologies, however, memory and memorialization is used for the sake of defining the “self” and the “other” through - boundaries along ethnic lines. The project investigates the ways in which human rights advocates understand, promote and mandate supposedly universal memorialization standards, asking whether in so doing they weaken or instead often actually - strengthen nationalism. Within the University College Dublin, School of Sociology, and under supervision of Prof Malešević, a world-known expert in nationalism, the goal of this project is to get 1) new theoretical framework for the critical - interdisciplinary study of human rights` memorialization policy; 2) new empirical insights into whether in different national contexts (in the Balkans and the Middle East) the prescribed standards of memory are being promoted, and if so, by whom and - to what ends; 3) to develop case and gender-sensitive and cost-effective policy recommendations for future implementation of the EU human rights` memorialization policies. Successful realization of the project will enable Dr David to get a tenure - track position at Hebrew University, where she will further use the acquired knowledge to search for innovative solutions to strengthen human rights. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Ireland - - - HRMN - - - H2020-MSCA-IF-2016 - - - 745922 - - - - - CONSIGLIO NAZIONALE DELLE RICERCHE - - - EUR 168 277,20 - - - Anchialine caves to understand evolutionary processes - - - EUR 168 277,20 - - - Italy - - - Research Organisations - - The goal of this project is to use the animal communities inhabiting anchialine environments as a model to investigate evolutionary patterns and processes in island-like marine habitats. Anchialine environments represent - world-wide distributed land-locked water bodies with marine origin. They are comparable to islands for terrestrial habitats as they encompass young, discrete habitats with comparable ecological conditions to the sea, thus providing independent - replicates of comparable evolutionary processes. All anchialine habitats previously investigated harbor high endemism, disharmonic communities, species with unique set of troglomorphic features, and old animal lineages interpreted as living fossils. - In the four research parts of this project, we will test each of these observations and the processes related to them by analyzing large data sets with both macroecological and phylogenetic methods and a broad theoretical perspective from the field - of evolutionary ecology, comparative evolution and island biogeography. This will facilitate to link the ecological and evolutionary processes observed in these habitats (easy to isolate and test due to the discrete and young nature of anchialine - habitats) with those affecting oceanic ecosystems, providing a tool for a deeper understanding of the marine biota. Whereas similar approaches are well characterized in terrestrial environments (e.g. island), they are missing in the ocean, obscuring - our understanding of the processes occurring there. - - 2019-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - ANCAVE - - - H2020-MSCA-IF-2016 - - - 745530 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 1 500 000 - - - Understanding the physical biology of adult blood stem cells - - - EUR 1 500 000 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The discovery of functional heterogeneity in normal and malignant stem cells has shifted our understanding of how single cells are subverted to drive cancer. To design therapies for diseases of stem cell origin and to better - provide cell populations for clinical applications, it is critical to understand this diversity at the single cell level. This proposal focuses on understanding the complex biology of normal and malignant stem cells and the impact of individual - mutations on clonal evolution by studying the physical and quantitative aspects of single blood stem cells. - - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - PHYSBIOHSC - - - ERC-2016-STG - - - 715371 - - - - - UNIVERSITY OF LEEDS - - - EUR 195 454,80 - - - Robotic Manipulation Planning for Human-Robot Collaboration on Forceful Manufacturing Tasks - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - This proposal addresses robotic manipulation planning for human-robot collaboration during manufacturing. My objective is to develop a planning framework which will enable a team of robots to grasp, move and position - manufacturing parts (e.g. planks of wood) such that a human can execute sequential forceful manufacturing operations (e.g. drilling, cutting) to build a product (e.g. a wooden table). - - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - United Kingdom - - - HumRobManip - - - H2020-MSCA-IF-2016 - - - 746143 - - - - - UNIVERSITY OF YORK - - - EUR 269 857,80 - - - Quantum Sensing for Biology - - - EUR 269 857,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Modern physics has contributed to the development of powerful instruments and diagnostic tools for biology and medicine, with a direct impact on both our well-being and life expectancy. Today, it is timely to ask if the novel - field of quantum information is ready to provide new methods for the life sciences. This proposal makes a step in this direction, introducing non-invasive quantum techniques for experimental biology, with potential applications to biomedical imaging. - My goal is to show how quantum correlations (entanglement or discord) can be exploited to realize a fully non-invasive form of spectroscopy, which can be safely applied to fragile materials, such as photo-degradable biological samples (DNA/RNA) or - in-vivo human tissues. These objectives are not met in today’s biology labs, where UV-light photometry heavily damages DNA/RNA samples, or in public hospitals, where X-ray scans expose patients to significant radiation doses, with non-negligible - risks of cancer. The basic rationale behind the use of quantum correlations relies on their superior capacity to detect small variations in the absorption properties of the materials, even when only a few photons are employed. By exploiting this - remarkable feature, I will prove the possibility of non-invasive testing of biological samples. My central task will be the design of a practical model of a quantum-enhanced photometer which is fully based on continuous-variable systems. This design - will involve the extension of quantum sensing and metrology to a more advanced double-box formulation where two channels, representing seeded and blank samples, are simultaneously probed. The realization of such a quantum-enhanced instrument would - allow for real-time continuous measurements of organic molecules and nucleic acids without any photo-degradation. - - 2020-07-06, ongoing project - - - 2017-07-07 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - QSB - - - H2020-MSCA-IF-2016 - - - 745727 - - - - - KOBENHAVNS UNIVERSITET - KOBENHAVNS UNIVERSITET - - - EUR 1 999 750 - - - New and Old Histones in Epigenetic Cell Memory - - - EUR 1 999 750 - - - Denmark - Denmark - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Cell type specific organization of DNA into chromatin is an important determinant of gene expression and cell identity. During cell division, epigenetic information in chromatin must be transmitted to daughter cells in order - to maintain cell identity or commit to a developmental program. However, it remains unknown how epigenetic states are inherited during cell division. Elucidating molecular mechanisms underlying epigenetic cell memory thus represents a major challenge - in biology critical to understand development and disease. - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Denmark - - - HISTONEMEMORY - - - ERC-2016-COG - - - 724436 - - - - - QUEEN MARY UNIVERSITY OF LONDON - - - EUR 183 454,80 - - - Developing a Bayesian technique to evaluate the validity of economic models: two applications to the Euro Area - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The 2007 financial crisis and the 2009 European sovereign debt crisis highlighted how difficult it is to build models that capture the dynamics of the economic system. The project develops a model evaluation technique that - allows a researcher to assess how much the economic models of interest to a researcher are supported by the data. The innovative technique set out in the project is developed in order to assist policy-makers address a wide variety of research - questions, and to help them achieve their goals – for example, predicting the impact of interest rate changes on a country’s economy. Two applications to monetary policy by the European Central Bank are developed. The first application studies - whether the data support a class of economic models used to assess monetary policy. The second application studies how successful monetary policy has been in counteracting deflationary pressures in the Euro Area. - - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - BMC-SVAR - - - H2020-MSCA-IF-2016 - - - 744010 - - - - - FIRAMIS UG - - - EUR 159 460,80 - - - Backreaction of Financial Networks: Risk Estimation and Asset-Management - - - EUR 159 460,80 - - - Germany - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The financial market is a relevant part of our economy. Its crisis spread all over the countries and affect our daily life. Understanding these phenomena has become a crucial field of academic research and a holy grail for - investors. In this project, I aim to study and develop models to forecast and manage the risk propagation along simplified structures called dynamical networks with particular emphasis on the morphological changes occurring as back-reaction to the - risk spread. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-SE - Society and Enterprise panel - - - Germany - - - FinNet - - - H2020-MSCA-IF-2016 - - - 750961 - - - - - COATING TECHNOLOGIES SL - - - EUR 158 121,60 - - - Novel industrial processes using the Atomic Layer Deposition technique - - - EUR 158 121,60 - - - Spain - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Different from chemical vapor deposition (CVD) and physical vapor deposition (PVD), atomic layer deposition (ALD) is based on saturated surface reactions. In this case, the thin films are grown in a layer-by-layer fashion - allowing sub-nanometer thickness control, low temperature depositions, good uniformity and superior step coverage on high specific surface area components compared to CVD and PVD. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-SE - Society and Enterprise panel - - - Spain - - - ALDing - - - H2020-MSCA-IF-2016 - - - 746954 - - - - - GOETEBORGS UNIVERSITET - - - EUR 173 857,20 - - - Defining the Role of Antioxidants on Cancer progression and metastasis - - - EUR 173 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - Antioxidants, by neutralizing ROS and ROS-induced DNA damages, are thought to protect against cancer. Recently this common view was challenged by the observation that antioxidants may accelerate tumor progression in mouse - models of lung cancer, by turning down the DNA-damage-gH2AX-p53 signaling pathway. This study raised new questions: Are antioxidants able to induce metastasis from benign tumors, by silencing p53 expression? Are cytosolic ROS equivalent to - mitochondrial ROS for lung cancer progression? - - 2018-02-28, Grant Agreement terminated - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - RAC - - - H2020-MSCA-IF-2015 - - - 707700 - - - - - WEIZMANN INSTITUTE OF SCIENCE - WEIZMANN INSTITUTE OF SCIENCE - - - EUR 150 000 - - - NovEl Strategies for treatIng tendon-to-bone injurieS - kiNESIS - - - EUR 150 000 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Body movement requires efficient transfer of force from contracting muscles to bone. Damage to the tendinous insertions is the 8th leading cause of disease burden and is the largest single cause of work loss in Europe. - Historically, approaches for improving healing in these attachment units have focused on modifying repair techniques and rehabilitation protocols. These methods are proven to be very ineffective, since failure rates of as high as 94% are often - reported. - - - 2018-09-30, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2016 - ERC-Proof of Concept-2016 - - - ERC-POC - Proof of Concept Grant - - - Israel - - - kiNESIS - - - ERC-2016-PoC - - - 737473 - - - - - KAROLINSKA INSTITUTET - - - EUR 173 857,20 - - - Characterizing Microbe-specific Immune Responses in the pathogenesis of Autoimmunity - - - EUR 173 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - Dysregulation in the balance of CD4+ T helper cell populations can severely alter susceptibility to a number of chronic inflammatory diseases, including inflammatory bowel disease (IBD). The incidence of IBD is dramatically - increasing in Europe and worldwide and its therapy represents an important unmet medical need, since a significant proportion of patients fail to respond to currently available immunotherapies. Therefore, a better characterization of the - immunological events underlying each form of IBD is of foremost importance. Increasing evidence points to the pivotal role of a dysregulated mucosal immune response to the intestinal microbiota in the pathogenesis of IBD. However, little is known - about the mechanisms contributing to the generation of commensal-specific adaptive immune responses, and whether their differential localization can shape severity and anatomical extent of the disease. Indeed, the intestines comprise anatomically - distinct regions that are exposed to different luminal antigens and this diversity eventually determines a regionalization of intestinal immune functions and microbiota-specific T cell responses. The aim of this proposal is to deeply characterize - microbiota-specific T cell responses generated under different inflammatory conditions, in terms of differentiation, plasticity, heterogeneity, function and homing potential. To this aim, the proposed work will combine the use of CBir1 TCR transgenic - mice, whose T cells recognize a microbial antigen that is immunodominant in IBD patients, and cutting-edge techniques such as single-cell RNA sequencing. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - MIRA - - - H2020-MSCA-IF-2016 - - - 746628 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - LINKOPINGS UNIVERSITET - IQUADRAT INFORMATICA SL - HERIOT-WATT UNIVERSITY - UNIVERSITAT POLITECNICA DE CATALUNYA - TECHNISCHE UNIVERSITAET DRESDEN - SIRADEL - ERICSSON AB - EDUCATIONAL OTE AE - TTI NORTE, S.L. - - - EUR 3 858 492,24 - - - Innovative Architectures, Wireless Technologies and Tools for High Capacity and Sustainable 5G Ultra-Dense Cellular Networks - - - EUR 3 858 492,24 - - - France - Sweden - Spain - United Kingdom - Spain - Germany - France - Sweden - Greece - Spain - - - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The fifth-generation (5G) is coming.Quo vadis 5G?What architectures, network topologies and technologies will define it?Are methodologies to the analysis, design and optimization of current cellular networks still applicable - to 5G? 5Gwireless is the first integrated and multi-disciplinary training-through-research network of ESRs and Senior Supervisors fully committed to re-architecting current cellular principles aiming at making 5G a reality, it will define and - optimize radically-changing architectures and technologies leading to a wholesale re-thinking of cellular operational principles & architectures, network topologies, transmission technologies and methods to their analysis, design and - optimization. It will recruit 15 ESRs having the objective of conducting top-notch research at national, European and international levels.ESRs will receive personalized training and will conduct theoretical and applied research on fundamental - challenges to the development of 5G systems and networks. According to the 5G Public-Private Partnership (5GPPP) recently formed by the EU, 5G networks need to be designed, engineered and optimized by relying on innovative technologies capable of - providing 1000 times higher capacity and a 90% reduction in energy consumption compared to the status quo.Such a fundamental and radical paradigm-shift in network design and architecture requires cross-sectoral skills&background and can very - unlikely be realized by researchers that have not received personalized training on innovative technologies and adequate methodological tools to their analysis.5Gwireless' mission is to create a vibrant EU-based training and research environment for - young researchers aiming at designing architectures, systems and algorithms for building the 5G cellular network of tomorrow. 5Gwireless is first step in that direction having the long-term target of preparing the first highly-selected & trained - class of competent academic researchers and industrial professionals. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - France - - - 5G Wireless - - - H2020-MSCA-ITN-2014 - - - 641985 - - - - - META GROUP SRL - EUROPEAN CROWDFUNDING NETWORK - EUROPEAN BUSINESS AND INNOVATION CENTRE NETWORK AISBL - - - EUR 472 468,75 - - - Supporting FET projects to reach out investors - - - EUR 472 468,75 - - - Italy - Belgium - Belgium - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - Other - - FET2RIN aims at facilitating collaborations to set the ground for the take up of FET projects by overcoming obstacles related to market outreach and accessing business leaders including entrepreneurs, early stage investors and - crowdfunding communities. - - 2018-11-30, ongoing project - - - 2015-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-CSA-FETTAKEUP-2015 - FET Take-Up Coordination and Support Activities 2015 - - - CSA - Coordination and support action - - - Italy - - - FET2RIN - - - H2020-FETOPEN-2015-CSA - - - 687110 - - - - - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH - EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH - UNIVERSITA DI PISA - - - EUR 1 876 215,30 - - - Understanding the mass scales in nature - - - EUR 1 876 215,30 - - - Switzerland - Switzerland - Italy - - - Research Organisations - Research Organisations - Higher or Secondary Education Establishments - - The experimental results of the first run of the Large Hadron Collider lead to the discovery of the Higgs boson but have not confirmed the dominant theoretical paradigm about the naturalness of the electro-weak scale, - according to which the Higgs boson should have been accompanied by supersymmetric particles or by some other new physics able of protecting the Higgs boson mass from quadratically divergent quantum corrections. - - 2020-11-30, ongoing project | - - - 2015-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Switzerland - - - NEO-NAT - - - ERC-2014-ADG - - - 669668 - - - - - UNIVERSITEIT LEIDEN - UNIVERSITEIT LEIDEN - - - EUR 1 075 109 - - - Democratic Secrecy: A Philosophical Study of the Role of Secrecy in Democratic Politics - - - EUR 1 075 109 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Transparency in politics is the mantra of democratic governance. Should state secrecy, such as classified intelligence programs or closed-door political bargaining be abolished? Despite its revered status, many feel that - complete transparency would undermine effective functioning of governments. Take the public responses to the Wikileaks disclosures: many of the disclosures were assessed favorably, but few people defended the idea of total transparency that inspired - them. - - 2020-07-31, ongoing project - - - 2015-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - DEMSEC - - - ERC-2014-STG - - - 639021 - - - - - THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN - - - EUR 183 454,80 - - - Delivering better fitness estimators for wildlife ecology and management and effective monitoring - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Fitness is a key concept in basic and applied ecology, and its traits are used to assess habitat quality and derive scientific knowledge used to design and implement management and conservation measures. Assessing fitness - requires considering several traits and trade-offs, and long-term data sets with individual identification that are rarely available. As a result fitness proxies such as offspring production are often used as substitute but these do not consider - variation in offspring survival and lifespan, which accounts for most variation in fitness is in long-lived species, like many endangered vertebrates. Many studies, and decisions supported by them, involve unknown biases as consequence of the - knowledge gap in the relationship between fitness and: the reliability of each proxy; trade-offs among different proxies; and among proxy/monitoring-effort combinations. - - - 2017-05-13, closed project | - - - 2015-05-14 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - BetMon - - - H2020-MSCA-IF-2014 - - - 659648 - - - - - UNIVERSITEIT LEIDEN - - - EUR 165 598,80 - - - Microscopic Surface Dynamics of Pt and Pt Alloy Electrocatalysts under operation conditions - - - EUR 165 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - By employing the in-situ electrochemical video-rate scanning tunneling microscopy (STM) at well-defined single crystal electrodes, we are going to study the surface dynamics of the atoms on Pt(111), Pt(553), Pt(533), - Pt(111)-Cu and Cu/Pt(111) surface alloy in the absence and presence of oxygen gas, with the aim to probe and understand the restructuring of Pt and Pt alloy catalyst of the fuel cell cathodes under the operation conditions. Simultaneously, in-situ - electrochemical surface Raman spectroscopy will be used to identify the surface species and their interaction with electrodes, using a version employing shell-isolated nanoparticles that is suitable for single-crystal electrodes. On the basis of the - observations of STM and Raman spectroscopy, theoretical calculations based on density functional theory (DFT) and Monte Carlo simulations will be carried out to understand the surface electronic structures and to mimic dynamical migrations of the - surface atoms. This should yield deep insight into the essential dynamic properties and the impact on the restructuring of these electrocatalysts under operation conditions. - - 2017-03-31, closed project - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - DYNECAT - - - H2020-MSCA-IF-2014 - - - 661145 - - - - - UNIVERSITEIT LEIDEN - - - EUR 177 598,80 - - - Cross-talk between inflammation and autophagy in tuberculosis - - - EUR 177 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - The increasing occurrence of multidrug-resistant Mycobacterium tuberculosis strains makes tuberculosis (TB) a key priority for infectious disease research. Inflammation and autophagy are two fundamental processes critical to - TB pathogenesis. Accumulating evidence shows that TB disease is worsened by deregulation of the inflammatory response. On the other hand, autophagy has recently emerged as a crucial host defence mechanism. Autophagy counteracts the ability of - mycobacteria to survive inside host cells and targets them for degradation. Autophagy is also thought to control the inflammatory response. However, the interaction between inflammation and autophagy in host defence against TB remains unclear. The - aim of my proposal is to use the well-established zebrafish model of TB to gain insight into this key question. Recently, the host laboratory discovered that the DNA damage-regulated autophagy modulator (DRAM1) protects against TB in the zebrafish - model. They also implicated this important autophagy regulator in inflammation, as it strongly affects expression of interleukin-1beta (IL1B). I have specific expertise in studying IL1B-mediated inflammation in zebrafish. Thus the proposed project - will be a great synergy between me and the host laboratory, which is leading in zebrafish infectious disease research. I will determine how modulation of autophagy or manipulation of IL1B levels reciprocally influence each other during TB disease. - The zebrafish model provides excellent tools to visualize these processes in vivo. Furthermore, I will take advantage of the host’s expertise in RNA sequencing and proteomics to study genome-wide effects of autophagy modulation on the inflammatory - response. A secondment will allow me to compare results in the TB model with a damage-induced inflammation model. The project will provide new insights into regulatory pathways that could potentially be intervened in treatment of TB or other - inflammatory diseases with common characteristics. - - 2018-01-17, closed project - - - 2016-01-18 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - Inflammafish - - - H2020-MSCA-IF-2014 - - - 655424 - - - - - IRISH TRADITIONAL MUSIC ARCHIVE/TAISCE CHEOL DUCHAIS EIREANN LBG - - - EUR 187 866 - - - Linked Irish Traditional Music Project - - - EUR 187 866 - - - Ireland - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The LITMUS (Linked Irish Traditional Music) project will focus on the development of the first linked open data (LOD) framework tailored to the needs of Irish traditional song, instrumental music, and dance (ITM), as well as - European and non-European traditional musics primarily propagated through oral transmission. LOD connects data from within & beyond knowledge domains; LOD ontologies are specially designed to represent knowledge structures and relationships. The - few existing LOD music ontologies do not adequately express ITM & other oral traditions, making LITMUS significant. Project activities include ontology development, LOD infrastructure creation, & development of a publicly-accessible LOD - pilot. LITMUS will impact the larger European cultural heritage community & beyond, providing a framework for other organisations to model & publish their own similar collections in LOD; reifying latent shared properties & traits - anecdotally known to exist in the folk music of countries with strong socio-historical links. The researcher is uniquely positioned for implementing the LITMUS project through her combination of depth & breadth of knowledge in ITM, research in - music information scholarship, & technological skills. Through LITMUS, the researcher will gain new technical skills, apply knowledge in multiple areas, gain insight into LOD industry research; synthesize current knowledge with new approaches - using LOD, & gain high-level publication & presentation opportunities, thus greatly enhancing her employability in the non-academic sector. A variety of non-academic and academic audiences will be engaged in dissemination & communication - of project results through presentations, demonstrations, videos, & workshops, including interdisciplinary music audiences. LITMUS will add value to ITMA's existing role as Project Partner & Content Provider for Europeana/Europeana Sounds - whilst establishing ITMA as an international research focal point for LOD & traditional musics. - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-SE - Society and Enterprise panel - - - Ireland - - - LITMUS - - - H2020-MSCA-IF-2016 - - - 750814 - - - - - UNIVERSITEIT LEIDEN - - - EUR 177 598,80 - - - Miniaturised Metabolomics Platform for Microvascular Research - - - EUR 177 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Preventing and treating progressive microvascular loss (i.e. rarefaction) is a major challenge in cardiovascular medicine. Microvascular disease is a multifactorial disease with no effective treatment. Long-term exposure to - adverse metabolic and haemodynamic conditions such as hypertension, obesity and diabetes can cause microvascular destabilisation, loss of tissue capillaries, and eventual organ failure. Interestingly, not all diabetic patients develop kidney failure. - The missing link to developing effective strategies for treating multifactorial diseases, including microvascular disease, is detailed mechanistic insight into the relationship between disease pathogenesis at the organ/cellular level at the - systemic/organism level. - - - 2018-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - Netherlands - - - METAFORA - - - H2020-MSCA-IF-2015 - - - 709077 - - - - - UNIVERSITEIT LEIDEN - UNIVERSITEIT LEIDEN - - - EUR 1 500 000 - - - Unravelling cross-presentation pathways using a chemical biology approach - - - EUR 1 500 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Immune therapies are therefore currently being pursued to reinvigorate the immune reaction against tumours. This is not trivial, as the right type of immune cells must be activated against a tumour-specific antigen. One method - to achieve this is by targeting tumour antigens to certain cross-presentation-promoting receptors on antigen presenting cells. The most intriguing of these is the mannose receptor (MR) as the method by which it does this is unknown. - - - 2020-04-30, ongoing project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - Crosstag - - - ERC-2014-STG - - - 639005 - - - - - AARHUS UNIVERSITET - - - EUR 212 194,80 - - - Understanding Social-Ecological Systems: Coupling population and satellite remotely sensed environmental data to improve the evidence base for sustainable development - - - EUR 212 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - In developing countries the majority of rural communities rely on natural resources and environmental products for food, fuel, building materials and medicines. Rapidly changing socioeconomic conditions can have important - consequences for environmental resources and ecosystem services. Consequently, the pressure that natural resources experience from population growth is a significant barrier to sustainable human development. This research project will broaden the - approach to sustainable development research by studying population-environment relationships using data with unrivalled spatial and temporal resolutions. The objectives of the research are to identify: (1) How satellite data can be used to estimate - aspects of environmental resources and ecosystem services important for livelihoods; (2) the relationships between household poverty and remotely sensed environmental conditions? And are these relationships consistent at different time periods? and; - (3) how changes in poverty relate to changes in environmental conditions and vice versa? To study these relationships household panel survey data and remotely sensed environmental data will be coupled using GIS and non-parametric Classification and - Regression Trees (CART) and random forests models which can handle and represent meaningfully the complex, nonlinear relationships between poverty and environment. The project will contribute to the Horizon 2020 aim of furthering sustainability - science by exploring how changes in society and the environment are linked and contribute to society beginning to think about interventions to managing environmental resources which could contribute to development and to understand the changes likely - in environmental resources when development occurs. It will contribute to the Work Programme as the fellow will gain new skills and training in geospatial and computational ecology and become an EU leading specialist in a research field with a lot of - growth potential. - - 2018-02-13, ongoing project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - USES - - - H2020-MSCA-IF-2014 - - - 656811 - - - - - UNIVERSITEIT LEIDEN - UNIVERSITEIT LEIDEN - - - EUR 1 499 522 - - - Forging Advanced Liquid-Crystal Coronagraphs Optimized for Novel Exoplanet Research - - - EUR 1 499 522 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The 39-m European Extremely Large Telescope (E-ELT) has the potential to directly observe and characterize habitable exoplanets, but current technologies are unable to sufficiently suppress the starlight very close to the - star. I propose to develop a novel instrumental approach with breakthrough contrast performance by combining coronagraphs based on brand-new liquid crystal technology, and sensitive imaging polarimetry. The novel coronagraphs will provide an - achromatic rejection of starlight even right next to the star such that exoplanets can be imaged efficiently in broadband light and characterized through spectropolarimetry. The coronagraphs will incorporate focal-plane wavefront sensing and - polarimetry to achieve an ultimate contrast of 1E-9, which will enable the E-ELT to observe habitable exoplanets. - - 2021-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - FALCONER - - - ERC-2015-STG - - - 678194 - - - - - UNIVERSITEIT LEIDEN - UNIVERSITEIT LEIDEN - - - EUR 2 500 000 - - - Cognitive control in context: Neural, functional, and social mechanisms of metacontrol - - - EUR 2 500 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Human behavior is commonly understood as emerging from a struggle between will and habit, i.e., between “intentional” processes driven by the current goal and “automatic” processes driven by available stimuli. This scenario - suggests that it is mainly the goal-related processes that render behavior adaptive. Based on a novel theoretical framework (the Metacontrol State Model, combined with the Theory of Event Coding) that is motivated by recent behavioral and - neuroscientific observations, I suggest an alternative view and argue that people can control the relative contributions of goal-driven and stimulus-driven processes to decision-making and action selection. In particular, people regulate the - interaction between these processes by determining the ratio between (goal) persistence and flexi-bility, depending on task, situation, and personal experience—a process that I refer to as “metacontrol”. The project aims to identify and trace - individual “metacontrol policies” (biases towards persistence or flexibility) and task- and condition-specific changes therein by means of behavioral, computational, and neuroscientific techniques, and by using virtual-reality methods. I shall study, - account for, and try predicting individual differences in the choice and implementation of such policies, identify and explain the cognitive and social consequences of adopting a particular policy, and investigate whether and how people can adopt - meta¬control policies from others—either intentionally or automati-cally. I shall also study whether and to what degree people use situational cues to automatize the implementation of suitable policies, and whether often-used, highly practiced - policies can become chron-ified and turn into a trait-like processing style, as suggested by cultural studies. - - 2021-11-30, ongoing project - - - 2016-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Netherlands - - - Metacontrol - - - ERC-2015-AdG - - - 694722 - - - - - UNIVERSITEIT LEIDEN - UNIVERSITEIT LEIDEN - - - EUR 2 000 000 - - - The neural basis of prosocial development in adolescence - - - EUR 2 000 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Adolescence is an important transition period in life, where individuals gain independence from their caregivers and develop into adults who pursue their own goals. Our understanding of this transition period has benefited - from two decades of research on brain development, in which it was discovered that adolescence represents a period of risk for heightened emotional reactivity, and that the developing brain in adolescence is much more plastic than previously thought. - - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - PROSOCIAL - - - ERC-2015-CoG - - - 681632 - - - - - THE UNIVERSITY OF LIVERPOOL - - - EUR 241 169,40 - - - How to help the hive? Incidence and impact of heritable microbes on bee health - - - EUR 241 169,40 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Honey bees provide both economic and societal benefits, from the honey and other commodities that they produce to the pollination services they provide. The loss of honey bee colonies and the current threats to their health - are of considerable concern to bee-keepers and biologists alike. This project seeks to examine how a particular aspect of honey bee biology – the symbiotic microbiome – impacts upon honey bee health. Studies in other systems reveal heritable microbes - as important modulators of disease susceptibility. This project will utilize the extensive network of bee samples across the US and UK to establish geographical patterns of heritable microbe presence in bees, and links to apiculture practice. It will - then use state of the art transcriptomic and genomic approaches to establish the links between Arsenophonus, a heritable symbiont known in bees, and bee health. It will then, combine with professional agencies responsible for bee health to use these - results to modify apiculture practice to establish better bee husbandry. Aside the research science completed, the project will train an EU scientist in state of the art genomic technologies and translation from discovery to applied science. It will - further transfer the training gained to EU hosts, both in discovery science and application. - - 2019-05-31, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - BeeSymOverSpace - - - H2020-MSCA-IF-2015 - - - 704382 - - - - - UNIVERSITEIT LEIDEN - UNIVERSITEIT LEIDEN - - - EUR 1 991 231 - - - Rethinking Disability: the Global Impact of the International Year of Disabled Persons (1981) in Historical Perspective - - - EUR 1 991 231 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Approximately 10% of the world’s population is estimated to be disabled and this number is expected to rise in the next few decades. People in different cultural settings ascribe different meanings to disability; consequently, - its repercussions are both culturally contingent and universal. This project brings together the local and global dimensions of disability and examines the interaction, tension and conflict between these two aspects by undertaking the first - comprehensive study of the far-reaching political, societal and cultural implications of the International Year of Disabled Persons (IYDP) which was organized under the auspices of the United Nations in 1981. A landmark event which appears to have - gone virtually unrecognized in scholarship; the IYDP was the first occasion to place disability into a global context by endorsing it authoritatively as a human rights issue and thereby raising the question as to how the concept may be understood in - a multicultural world. There will be four closely-related objectives: 1. to examine the IYDP’s impact on human rights discourses and to scrutinize their applicability within global settings; 2. to document the IYDP’s contribution to emancipation and - social change and to consider the different trajectories of emancipation in various parts of the world; 3. to assess the ways in which the IYDP influenced everyday life experiences, galvanized identity formation and inspired the emergence of a - distinct subculture; 4. to analyze the transnational exchanges and knowledge transfer in conjunction with the IYDP and to examine how the Western oriented discourses penetrating the developing world interacted with the local environment. The - project’s innovative contribution and academic impact lies in connecting the IYDP to broader political, social and cultural processes in the last quarter of the twentieth century and thereby bringing disability in a global context to the attention of - mainstream historical scholarship. - - 2020-09-30, ongoing project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - DISABILITY - - - ERC-2014-CoG - - - 648115 - - - - - UNIVERSITEIT LEIDEN - UNIVERSITEIT LEIDEN - - - EUR 1 999 960 - - - Embedding Conquest: Naturalising Muslim Rule in the Early Islamic Empire (600-1000) - - - EUR 1 999 960 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - What made the early Islamic empire so successful and have we missed the story by neglecting crucial evidence? The 7th-century Arab conquests changed the socio-political configurations in the Mediterranean and Eurasia forever. - Yet we do not really know how the Arabs managed to gain dominance of this vast, ethnically, religiously and linguistically diverse area which had its own, long imperial traditions, and to make this a sustainable enterprise. What built the empire, and - what held it together? Scholarship to date has overwhelmingly relied on ‘literary’ sources in Arabic (e.g. chronicles, legal treatises, theological tracts), composed centuries after the conquests and shaped by court politics at their time of writing. - This has created a false impression of the embedding of Muslim rule as a top-down process, directed from the centre, built on military coercion and control through administrative systems. Now, however, ‘documentary’ sources in multiple languages on - papyrus, leather and paper from all over the empire (e.g. letters, contracts, fiscal accounts, petitions, decrees, work permits) are becoming increasingly available, with the PI in an internationally leading role. These sources, whose impact has been - limited by linguistic and disciplinary boundaries, offer a direct, contemporary view of how the empire worked on the ground, and how political and social structures were experienced, modified and appropriated by its subjects.This project will - uniquely incorporate all available documents reflecting Muslim rule from the first 400 years of Islam, to reconstruct the system of social relations that enabled the crucial transition from a conquest society to a political organism that survived the - breakdown of central caliphal control, and remains the region’s benchmark model today. It will critically advance our understanding of a world historical event, make a radically new contribution to empire studies, and connect and synergise area - studies and disciplinary inquiry. - - 2021-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - EMBEDDING CONQUEST - - - ERC-2015-CoG - - - 683194 - - - - - UNIVERSITEIT LEIDEN - UNIVERSITEIT LEIDEN - - - EUR 2 300 962 - - - Exoplanet atmospheres as indicators of life: From hot gas giants to Earth-like planets - - - EUR 2 300 962 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This is a proposal to use a new ground-breaking spectroscopic technique to study the atmospheres of extrasolar planets. Understanding planet atmospheric processes and their evolutionary histories is crucial for unambiguously - identifying biomarker gases, and forms the main driver behind the enormous surge in exoplanet atmospheric research. - - - 2021-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Netherlands - - - EXOPLANETBIO - - - ERC-2015-AdG - - - 694513 - - - - - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - KOBENHAVNS UNIVERSITET - UNIVERSITEIT LEIDEN - - - EUR 2 371 132 - - - From Fermi to Planck : a bottom up approach - - - EUR 2 371 132 - - - Switzerland - Switzerland - Denmark - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The Standard Model of particle physics is a hugely successful theory that has been tested in experiments at ever increasing energies, culminating in the recent discovery of the Higgs boson. Nevertheless, some major riddles - cannot be addressed by the Standard Model, such as neutrino oscillations, the existence of Dark Matter, the absence of antimatter in the Universe. New fundamental principles, interactions and unknown yet particles are required to address these - questions. Much of the research done during the last three decades on physics ‘beyond the Standard Model’ (BSM) has been driven by attempts to find a ‘natural’ solution of the hierarchy problem: why the Planck and the electroweak scales are so - different. The most popular approaches to this problem predict new particles with the masses right above the electroweak scale. - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Switzerland - - - NuBSM - - - ERC-2015-AdG - - - 694896 - - - - - FUNDACIO CENTRE DE REGULACIO GENOMICA - FUNDACIO INSTITUT DE CIENCIES FOTONIQUES - EUROPEAN MOLECULAR BIOLOGY LABORATORY - THE HEBREW UNIVERSITY OF JERUSALEM - LABORATORY IMAGING SPOL SRO - Idea Bio-Medical Ltd. - - - EUR 3 988 752,50 - - - CellViewer: super-resolution systems microscopy to assess pluripotency and differentiation of stem cells at single cell level - - - EUR 3 988 752,50 - - - Spain - Spain - Germany - Israel - Czech Republic - Israel - - - Research Organisations - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - In this ambitious and multi-disciplinary proposal, we aim to develop new technologies that will allow us to visualize in single cells, in parallel and at the systems level, DNA, mRNAs and proteins with nanoscale resolution. We - will refer to these novel technologies as the ‘CellViewer’: a unique cutting-edge high-throughput super-resolution (SR) microscopy approach (including new hardware and software development) to collect at high-resolution a large amount of spatial and - dynamic information in single cells. ‘CellViewer’ will allow us to study the mechanisms of mouse embryonic stem cell (mESC) self-renewal and differentiation upon application of specific stimuli, as a specific test case. We will analyse in single - cells with high throughput, DNA remodelling at multiple specific gene loci and their corresponding production, distribution and kinetics of mRNA and protein products. We will collect a large amount of dynamic and nanoscale spatial information that - will lead us to build predictive models of the phenotypic output from specific input stimuli. In turn, we will be able to develop a mechanistic understanding of how mESCs maintain their stemness or commit to differentiation. The partners of - CellViewer are internationally recognized experts from academia and industry in the fields of stem cell and chromatin biology, super-resolution microscopy, quantitative modelling of biological systems, and hardware and software development. This team - as a whole is uniquely suited to bring Systems Biology into the era of single cell analysis, which will be a paradigm shift in the way cellular systems will be studied. - - 2020-01-31, ongoing project - - - 2016-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-1-2014 - FET-Open research projects - - - RIA - Research and Innovation action - - - Spain - - - CellViewer - - - H2020-FETOPEN-2014-2015-RIA - - - 686637 - - - - - UNIVERSITEIT LEIDEN - UNIVERSITEIT LEIDEN - - - EUR 2 460 500 - - - Father Trials: Hormonal and Behavioral Experiments on Prenatal and Postnatal Parenting - - - EUR 2 460 500 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Fathers have largely been neglected in parenting research -- although they constitute about 50% of parents. The aim of the proposed project is to test the hypothesis that fathers’ parenting is under hormonal control and can be - changed by behavioral and hormonal interventions. I propose a series of randomized controlled trials (RCT) focusing on a critical phase of parenthood: the transition to having the first baby. I will test whether experiments that modulate oxytocin and - testosterone levels enhance fathers’ neural processing of infant signals and of threats to the infant and stimulate fathers’ parenting quality and involvement in parenting. - - - 2020-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Netherlands - - - FATHER TRIALS - - - ERC-2014-ADG - - - 669249 - - - - - UNIVERSITA CA' FOSCARI VENEZIA - - - EUR 180 277,20 - - - Nanomaterials Ecological Risk Assessment: A study of the long-term effects and risks of nanoscale Iron Oxide used in plastic composites in the aquatic environment - - - EUR 180 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - The nanoform of Iron Oxide (n-Fe2O3) is a large-volume substance used in pigments. Nanoscale Fe2O3 pigments are used to a significant extent in consumer products such as household appliances made of coloured plastic - composites. This application implies high probability of n-Fe2O3 release into the aquatic environment (especially during end-of-life processing of the plastics), where n-Fe2O3 may pose risks to freshwater and sediment organisms. Presently, very - little is known about the biological interactions and the ecological risks of n-Fe2O3, as the available information addresses only short-term effects of pristine n-Fe2O3. Therefore, the goal of NanoERA is to develop concepts and methods, and to - generate data to predict the long-term ecological effects and risks of n-Fe2O3 (fragments) released from end-of-life processing of a coloured plastic composite into the aquatic environment and to compare them to the pristine n-Fe2O3 used to produce - the composite. In order to achieve this, the fellow will analyse how the physicochemical properties of the n-Fe2O3 (fragments) change in environmental (i.e. freshwater and sediment) and biological (cell culture) media and how these changes affect the - biological interactions of these materials in aquatic organisms. The generated ecotoxicological effects data will be used to derive dose-response relationships and to quantitatively estimate the long-term ecological risks of the n-Fe2O3 (fragments). - - - 2017-07-02, closed project - - - 2015-07-03 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - NanoERA - - - H2020-MSCA-IF-2014 - - - 660960 - - - - - UNIVERSITEIT LEIDEN - - - EUR 165 598,80 - - - Isis, Images and Agency. The Creation, Use and Perception of Religious Iconography Concerning the Egyptian Gods in the Hellenistic and Roman Worlds - - - EUR 165 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - "In the Hellenistic and Roman worlds, the Egyptian goddess Isis was remarkably popular along with the deities related to her, such as Sarapis, Harpocrates and Anubis. Tens of thousands of objects, from a wide variety of - contexts and periods, convey images that attest to the immense success of these cults. Both rich and coherent, this corpus of transcultural imagery provides an excellent laboratory for the study of the creation, use and perception of ancient - figurative media, especially in terms of agency. Previous research on this religious iconography has only wielded a fragmented vision, paying little attention to contexts and media. However, these images can only be understood in relation to one - another and as part of their sociocultural and religious networks. Since 2013, reconstituting this overview has been the aim of a Thesaurus whose catalogues gather all Isiac images for every kind of medium, highlighting the contextualised objects and - questioning what they meant and did. The progress of this collective undertaking allows me now to present a research project crucial to many categories of historians working on visual (material) culture. By reconstituting the history of Isiac images - throughout various types of production, the Thesaurus demonstrates how figurative systems were constantly interacting and evolving during Antiquity. It enables us to ask new questions on the creation, use and perception of these object-images from - both a synchronic and diachronic perspective. The synthesis emerging will form a "historical grammar" revealing the functioning of this figurative culture and its impact on ancient societies. With the largest part of the Thesaurus now available, - Leiden University provides the best current academic context for the more interpretative and synthesising parts of the research. By partaking in a more conceptual research culture, this experience will have a decisive impact on my scientific - development and will open up numerous new perspectives." - - 2019-01-31, ongoing project - - - 2017-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - IsImAg - - - H2020-MSCA-IF-2015 - - - 702875 - - - - - NATURAL ENVIRONMENT RESEARCH COUNCIL - - - EUR 195 454,80 - - - Nanomaterial surface interactions at the molecular level and their impact on ecotoxicity - - - EUR 195 454,80 - - - United Kingdom - - - Research Organisations - - As nanotechnology continues to advance at an exponential rate, new products are continuously introduced into the market for research and consumer use. Engineered nanomaterials (ENMs), the functional components in these - products, are often specifically designed to exploit the unique properties that nanomaterials exhibit; however, there is a widespread uncertainty on how these new properties may also potentially translate into novel risk issues in the environment. In - particular, their high specific surface area and surface reactivity may promote distinct interactions with organisms particularly at the lower trophic levels. This can depend on both the intrinsic and extrinsic properties of ENMs, and can be affected - by the formation of an “eco-corona”, which is composed of environmentally derived macromolecules from the milieu in which the ENMs are exposed that adsorb to the ENMs surface. However, understanding these interactions at the molecular level and their - mechanistic consequences are severely limited and technically challenging, requiring a cross discipline approach. This project aims to address this knowledge gap by uncovering the underlying mechanisms for the formation and persistence of eco-coronas - on a range of ENMs by combining fundamental ENM chemistry, environmental toxicology, advanced optical and mass spectroscopy and imaging techniques. In particular, this project will apply surface enhanced spectroscopic methods to characterise - eco-corona composition and evolution and how this affects ENM interactions with, and impact upon unicellular organisms. By correlating the eco-corona composition with uptake route (or accumulation at external membrane) and toxicity response, and by - investigating how these ENMs are partitioned within model species, the project proposes to identify the molecular basis that determines the fate and toxicology of ENMs in the environment. - - 2017-10-04, closed project - - - 2015-10-05 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - MolNANOtox - - - H2020-MSCA-IF-2014 - - - 660565 - - - - - UNIVERSITEIT LEIDEN - UNIVERSITEIT LEIDEN - - - EUR 1 999 733 - - - Persia and Babylonia: Creating a New Context for Understanding the Emergence of the First World Empire - - - EUR 1 999 733 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The Persian Empire (539-330 BCE) represented a new political order in world history. At its height, it united a territory stretching from present-day India to Libya. It was three times as large and twice as long-lived as the - previously most successful polity (Assyria), and it would take 2,000 years before significantly larger empires emerged in early modern Eurasia. - - - 2021-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - Persia and Babylonia - - - ERC-2015-CoG - - - 682241 - - - - - UNIVERSITEIT LEIDEN - - - EUR 174 864,60 - - - The Power of Silence: A Medical Anthropological Approach to AIDS Care Narratives - - - EUR 174 864,60 - - - Netherlands - - - Higher or Secondary Education Establishments - - Despite the widespread availability of antiretroviral medication, the global AIDS epidemic has not been halted yet and stigmatization of people living with HIV and AIDS continues in most parts of the world. While the social - scientific analysis of narratives of people living with HIV/AIDS (PLWHA) has proven crucial in understanding challenges in AIDS care worldwide, the silences that structure such narratives remain under-theorized. Current studies signal that silences - may be defenses and active strategies rather than passive responses to stigma, but critical questions remain on how to study, conceptualize and interpret what is unspeakable and unspoken, and sometimes even unthinkable. - - - 2018-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Netherlands - - - AIDSsilences - - - H2020-MSCA-IF-2015 - - - 707562 - - - - - UNIVERSITEIT LEIDEN - UNIVERSITEIT LEIDEN - - - EUR 1 500 000 - - - Biomimetic Copper Complexes for Energy Conversion Reactions - - - EUR 1 500 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Water oxidation (WO) and oxygen reduction (OR) are crucial reactions to produce and to consume solar fuels. It is important that WO and OR occur with very high catalytic rates with only a very small thermodynamic driving force - (i.e. a small overpotential). In these terms, natural catalysts perform significantly better than the artificial systems. Especially the copper enzyme Laccase operates fast at a low overpotential. In principle one could use the same design principles - used in the enzymatic systems to produce artificial catalysts for OR and WO. It is envisioned that for the most ideal OR and WO catalysts: - - 2020-04-30, ongoing project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - Cu4Energy - - - ERC-2014-STG - - - 637556 - - - - - UNIVERSITEIT LEIDEN - - - EUR 165 598,80 - - - INVESTIGATING EVIDENCE OF HIGH-MASS VARIATIONS OF THE STELLAR INITIAL MASS FUNCTION - - - EUR 165 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - One of the most important questions in the study of galaxy evolution is the assumption that stars formed within star clusters with a preferred mass distribution (IMF) independent of time and environment. Major advances in - understanding mainly the low-mass IMF variations have been made in the past decade, however, relatively a little attention has been paid to the high-mass IMF. As such some critical questions remain: Does the high-mass IMF vary as a function of time - and environment? Is it appropriate to describe the high-mass IMF with a single power-law as we do now? The multi-wavelength datasets that are becoming available now can address these questions. - - - 2019-01-22, ongoing project - - - 2017-01-23 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - EHMVSIMF - - - H2020-MSCA-IF-2015 - - - 707693 - - - - - UNIVERSITA DEGLI STUDI DI MACERATA - UNIVERSITEIT UTRECHT - MILITOS SYMVOULEUTIKI A.E. - MECCANO SPA - EUROPEAN QUALITY INSTITUTE SRL - OULUN YLIOPISTO - STICHTING WAAG SOCIETY - OULUN KAUPUNKI - STEFAN MARZELLI - UNIVERSITY OF ULSTER - STICHTING HAS KENNISTRANSFER EN BEDRIJSOPLEIDINGEN - FOOD NATION CIC - TARAS SHEVCHENKO NATIONAL UNIVERSITY OF KYIV - - - EUR 828 000 - - - Grey and green in Europe: elderly living in urban areas - - - EUR 828 000 - - - Italy - Netherlands - Greece - Italy - Italy - Finland - Netherlands - Finland - Germany - United Kingdom - Netherlands - United Kingdom - Ukraine - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Other - Other - Higher or Secondary Education Establishments - - The EU has to face many challenges in achieving a more balanced regional development and sustainable economic recovery. Many of those challenges have to do with the ageing population trend, urbanization and environment under - distress. More liveable and efficient communities is a target to be reached in Europe, where the “silver hair” trends can become a challenging opportunity, from a social, economic and cultural perspective. Despite those challenges are strongly - interlinked, solutions provided in urban contexts not often pay due attention to the social process underlying urban trends and to the needs and behaviour of elderly citizens. - - - 2018-11-30, ongoing project - - - 2014-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Italy - - - GRAGE - - - H2020-MSCA-RISE-2014 - - - 645706 - - - - - UNIVERSITA DI PISA - - - EUR 259 558,20 - - - Innovative high temperature thermal energy storage concept for CSP plants exceeding 50% efficiency - - - EUR 259 558,20 - - - Italy - - - Higher or Secondary Education Establishments - - Energy provision is a big challenge for our Society, being the present production/consumption paradigm not sustainable. To change current trends, a large increase in the share of Renewable Energy Sources (RESs) is crucial. The - effectiveness of Thermal Energy Storage (TES) poses Concentrated Solar Power (CSP) systems at the forefront, as the first dispatchable option among all intermittent RESs. In order to realize the CSP potential, the efficiency of the adopted Power - Conversion Units (PCUs) must grow over 50%, entailing temperature levels of the order of 1000 °C: promising solutions are based on Brayton thermodynamic cycles. This project stems from the observation that no existing TES option can be coupled to - such PCUs and/or work at these temperatures, and aims at filling this gap. Three interrelated research objectives are proposed, to prove the feasibility and assess the potential of - - 2019-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Italy - - - GLASUNTES - - - H2020-MSCA-IF-2014 - - - 656753 - - - - - UNIVERSITEIT LEIDEN - UNIVERSITEIT LEIDEN - - - EUR 150 000 - - - Membrane fusion mediated dermal allergy immunotherapy - - - EUR 150 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In this project we aim to develop a new delivery platform for allergy vaccines with a high efficacy and a high safety profile combining membrane fusion-mediated delivery and microneedle-based dermal delivery. - - 2016-08-31, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2014 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Netherlands - - - DermalTherapy - - - ERC-2014-PoC - - - 665684 - - - - - UNIVERSITEIT LEIDEN - UNIVERSITEIT LEIDEN - - - EUR 150 000 - - - Development of a potent dual GCS/GBA2 inhibitor as a best in class Gaucher therapeutic - - - EUR 150 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Gaucher disease (GD) is an autosomal recessive disorder caused by deficient activity of acid glucosylceramidase (GBA1). Most patients feature a non-neuronopathic (type 1) course of disease and are treated by either enzyme - replacement therapy (ERT – administration of recombinant GBA1) or substrate reduction therapy (SRT – treatment with the iminosugar, Zavesca or the ceramide mimic, Eliglustat – inhibitors of glucosylceramide synthase (GCS)). These therapeutic agents - do not prevent neurological symptoms in patients suffering from neuronopathic Gaucher forms (types 2/3) and there is thus an unmet medical need for these patients. Potent GCS inhibitors reduce glucosylceramide (GlcCer), the substrate of GBA and the - storage material in Gaucher, and also higher glycosphingolipids including gangliosides and globosides, the causative storage materials in Tay-Sachs disease, GM1 gangliosidosis and Fabry disease. We have found a highly attractive lead, BiPheDNM 7 - (Figure C below), which we plan to further develop towards a phase I/II clinical candidate. This proof of concept project will result in a packet comprising this lead molecule, accompanied by all the relevant data and tools to start phase I/II - clinical development together with a pharmaceutical partner. - - 2018-02-28, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2015 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Netherlands - - - Sphingolead - - - ERC-2015-PoC - - - 693039 - - - - - UNIVERSITEIT LEIDEN - - - EUR 177 598,80 - - - Rare Earth Supply Chain and Industrial Ecosystem: A Material Flow Assessment of European Union - - - EUR 177 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Europe is the leading importer and consumer of rare earth minerals both in mineral and applied forms. Europe is almost dependent on others for imports of these mineral resources, despite the fact that engineering and - manufacturing are backbone of many European economies. The criticality of these minerals were highlighted in European Commission’s Report of the Ad hoc Working Group on defining critical raw materials published in 2010 as well as 2014. - - - 2017-09-30, closed project - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - REE Value Chain - - - H2020-MSCA-IF-2014 - - - 656998 - - - - - UNIVERSITEIT LEIDEN - UNIVERSITEIT LEIDEN - - - EUR 150 000 - - - Empowering expectations for health and disease: Development of a pioneering training tool - - - EUR 150 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Expectations about health and disease are known to directly affect health and treatment outcomes. In the EXPECT-HEALTH project, my research group is unravelling the central mechanisms of how expectations affect immune and - endocrine responses and related health outcomes, through the use of pioneering multidisciplinary methods in healthy and clinical populations. Ultimate goal of gaining this knowledge is to apply it in innovative therapeutic interventions. - - - 2018-01-31, closed project - - - 2016-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2015 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - Netherlands - - - TRAIN-HEAL-TH - - - ERC-2015-PoC - - - 692671 - - - - - UNIVERSITEIT LEIDEN - - - EUR 242 929,80 - - - Predicting Cardiotoxicity Induced by Kinase Inhibitors: From Systems Biology to Systems Pharmacology - - - EUR 242 929,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Kinase inhibitors (KIs) are a major class of highly effective anti-cancer drugs. Unfortunately, therapeutic use of KIs is often associated with cardiotoxicity (CT), a serious adverse condition which limits their use. This - fellowship aims to develop mathematical systems pharmacology models for KI-induced CT. These models will be used to identify predictive CT signatures that will allow to decrease CT risk of new KIs. This innovative multi-disciplinary approach consists - of integrating mathematical systems pharmacology modelling, with state-of-the-art experimental data generation. To this aim, KIs with different magnitudes of CT will be selected based on clinical adverse event databases. Human cardiomyocytes derived - from pluripotent stem cells will then be treated with the selected KIs and in combination with CT modifying drugs. The effect of these treatments on changes on untargeted mRNA and protein expression will be measured and then analyzed using network - modelling. This approach allows identification of key regulatory proteins. The selected proteins will then be quantified over time along with cardiomyocyte health markers. With this data, dynamical models will be developed to capture the relationship - between exposure to KIs and the effects on protein expression and cardiomyocyte health over time. Ultimately these models will allow generation of predictive network-based dynamically-weighted signatures for CT. - - 2018-12-05, ongoing project - - - 2015-12-06 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Netherlands - - - CARDIOTOX - - - H2020-MSCA-IF-2014 - - - 661588 - - - - - OT BIOELETTRONICA DI BOTTIN ANDREA E MERLO ENRICO & C. S.N.C. - - - EUR 168 277,20 - - - wireless Body Area Networks for high density MYOelectric neurorehabilitation technologies - - - EUR 168 277,20 - - - Italy - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The next generation of rehabilitation systems will require the evaluation and restoration of the motor impairment using neural information. For this purpose, noninvasive multichannel electromiographic (EMG) technologies are - the most promising tools for research and clinical neurorehabilitation applications. Unfortunately, the current systems for high-density (HD) EMG recordings require long cables that impose significant restrictions on the patients and limit free - movement. Moreover, the integration of such bulky systems into current rehabilitative exoskeletons may be problematic. For these reasons, the project MyoBan aims to develop an innovative portable HD EMG system based on recent standards designed for - the next generation of wireless body area networks. The proposed system will exploit the spatial and temporal characteristics of the surface EMG signals to reduce the data-rate and optimize transmission parameters (e.g. transmitting power, specific - absorption rate, real-time processing, etc.). The final aim will be the production of small HD EMG sensors that can be placed on the surface of multiple muscles of the patients with minimal invasiveness and high efficiency. The project will combine - expertise in several fields: telecommunication, biomedical signal processing, medical information technologies and neurorehabilitation. The MyoBan is expected to produce substantial progress in the research and clinical applications of - neurorehabilitation technologies for motor restoration. - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-SE - Society and Enterprise panel - - - Italy - - - MyoBan - - - H2020-MSCA-IF-2016 - - - 753048 - - - - - INSTITUTO DE MEDICINA MOLECULAR - - - EUR 160 635,60 - - - Tracking γδ T cell development and TCRγδ proximal signalling - - - EUR 160 635,60 - - - Portugal - - - Research Organisations - - T cells are key constituents of our immune system. Two types of T cells are conserved evolutionary and across species: αβ and γδ T cells. While αβ T cells have been intensively studied during the last decades, our knowledge on - the development and activation of γδ T cells is still limited. Recently, γδ T cells have become increasingly attractive for immunotherapy of cancer due to efficient killing of tumour cells independently of major histocompatibility complex (MHC) - antigen presentation. The proposed project will elucidate how T cell receptor (TCR) signalling is initiated in γδ T cells; and how it contributes to the developmental programming of γδ T cell subsets strongly implicated in cancer immunity. - - 2019-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Portugal - - - DevoSignGammaDelta - - - H2020-MSCA-IF-2016 - - - 752932 - - - - - UNIVERZITA KOMENSKEHO V BRATISLAVE - - - EUR 153 381,60 - - - Towards Highly-Efficient Two-Photon Absorbing Sensitizers within a Confined Chromophore Space:From Computer-Aided Design to New Concepts and Applications - - - EUR 153 381,60 - - - Slovakia - - - Higher or Secondary Education Establishments - - Materials exhibiting large two-photon absorption (TPA) are in great demand to meet the needs of emerging laser technologies and applications in medicine and biomedical engineering (bioimaging, photodynamic therapy, - microfabrication). Most design strategies to enhance TPA activity rely on construction of extremely large pi-conjugated molecules, which are not appreciated in practice due to difficulties connected with their synthesis or low cell permeability. The - fellow recently demonstrated that significant TPA enhancement can be achieved by small perturbations in the heteroaromatic unit, but these effects are often hardly predictable or chemically counter-intuitive. - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Slovakia - - - TWOSENS - - - H2020-MSCA-IF-2016 - - - 752285 - - - - - UNIVERSITY OF WOLVERHAMPTON - - - EUR 195 454,80 - - - Impact of Environmental Tobacco Smoke on Incidence and Outcomes of Dementia. - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Environmental Tobacco Smoke (ETS) remains prevalent globally. Its association with dementia is unclear. We propose to investigate impacts of ETS on dementia risk and outcomes, and examine levels and determinants of ETS - exposure post dementia. In a case-control study in the UK we will recruit 150 elders aged>=75 years with newly diagnosed dementia, 150 with already diagnosed dementia and 150 without dementia from the Royal Wolverhampton hospital. Each participant - will be interviewed for socio-demography and risk factors and have saliva samples taken for cotinine analysis. Using multivariate logistic regression models we will examine the association of ETS measured by cotinine with newly diagnosed dementia, - and identify factors influencing ETS exposure in people with already diagnosed dementia. We will analyse data from a cohort of 6071 participants aged >=60 years in China, who had the details of ETS exposure recorded in a 5-province health survey - in 2007-2009 and were re-interviewed in 2010-2012 to diagnose incident dementia. We will examine incident dementia in relation to baseline ETS exposure, and the impact of ETS exposure on mortality and multimobidity in participants with dementia using - multiple adjusted Cox regression models. In the UK we will further run 2 focus groups and explore preventive measures of ETS exposure in older people with and without dementia. Our rich data, including a biomarker elevated upon exposure to ETS will - offer internationally applicable insights into the impacts of ETS on dementia incidence and outcomes. Throughout the research project, use of varied study and research methodologies and rigourous training courses, our Fellow will develop his - leadership skills and further his career in public health research. The project will strengthen a long-term collaboration between China and EU partners, and will provide Europe with new data to prevent dementia and to reduce ETS. - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - DEMETS - - - H2020-MSCA-IF-2016 - - - 752920 - - - - - UNIVERSITA DI PISA - Consortium Ubiquitous Technologies S.c.a.r.l. - UNIVERSITAT ROVIRA I VIRGILI - GENERATION RFID S.L. - INSTITUT POLYTECHNIQUE DE GRENOBLE - ARDEJE SARL - - - EUR 913 500 - - - ChiplEss MultisEnsor Rfid for GrEen NeTworks - - - EUR 913 500 - - - Italy - Italy - Spain - Spain - France - France - - - Higher or Secondary Education Establishments - Other - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - EMERGENT takes up the broader scope of Marie Skłodowska-Curie Research and Innovation Staff Ex-change Scheme of promoting knowledge-sharing-based cooperation and moves its steps forward to actual-ly support and facilitate the - movement of skilled people between academia and industry committed to work on a research topic dealing with green chipless RFID tags and sensors. - - 2017-12-31, closed project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Italy - - - EMERGENT - - - H2020-MSCA-RISE-2014 - - - 645771 - - - - - SARDEX SRL - THE UNIVERSITY OF HERTFORDSHIRE HIGHER EDUCATION CORPORATION - UNIVERSITAT PASSAU - Fachhochschule Salzburg GmbH - - - EUR 99 978,75 - - - Interacting Decentralized Transactional and Ledger Architecture for Mutual Credit - - - EUR 99 978,75 - - - Italy - United Kingdom - Germany - Austria - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The objective of INTERLACE is to use the Abstract State Interaction Machines framework (CoreASIM) open source output of the FP7 FET project BIOMICS to develop a decentralized transactional and ledger architecture demonstrator - for B2B mutual credit. INTERLACE will add to the work already started by its coordinator, Sardex s.r.l., to develop this architecture. SARDEX will use the Open Transaction protocol (OTX) as an intermediate solution between fully centralized and - distributed architectures. OTX involves a pool of Auditor nodes to validate the transactions executed by each Notary node. In INTERLACE there will be only one central Notary, as a first step from the current centralized server towards a more - distributed architecture. The persistence layer will be implemented as a private blockchain stored on the central server to create a sparse 160-bit address space implemented as a binary hash tree. This approach achieves continuity with the existing - solution while also enabling scalability to multiple circuits (multiple Notaries) under the same mathematical and computational framework. SARDEX has been operating successfully an electronic, B2B, zero-interest mutual credit system on the island of - Sardinia since 2009. The Sardex system (also known as Circuito di Credito Commerciale) enables local economic actors (SMEs in particular) to trade with each other in a trustful and circular fashion with a unique digital trade credit unit. It does - this by monetizing the spare capacity of the local economy in the form of mutual, and taxable, credit between participating companies, at zero interest, on a strong basis of trust, solidarity, and local cultural identity. Therefore, INTERLACE will - address very effectively the Workprogramme objective to generate socio-economic impact from EU-funded research. INTERLACE is uniquely positioned to integrate the very advanced results of BIOMICS directly in a deeply innovative, transformative, and - successful fintech platform for B2B trade. - - 2018-10-31, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-04-2016-2017 - FET Innovation Launchpad - - - CSA - Coordination and support action - - - Italy - - - INTERLACE - - - H2020-FETOPEN-4-2016-2017 - - - 754494 - - - - - UNIVERSITE DE BORDEAUX - - - EUR 173 076 - - - Dental anthropology at the Pleistocene-Holocene transition – insights on lifestyle and funerary behaviour from Neolithic Liguria (Italy) - - - EUR 173 076 - - - France - - - Higher or Secondary Education Establishments - - The purpose of the proposed research is using dental anthropology to contribute to our understanding of lifestyle, societies, and belief systems at the Pleistocene-Holocene transition. This is a key moment of our past, during - which we shifted from hunting-gathering to the production economy on which we still live. The project will mainly focus a large (150-200 individuals) Neolithic (8-4,000 BP) skeletal assemblage from Liguria (north-western coast of Italy). The research - will also involve comparisons with other Neolithic, Mesolithic (10-8,000 BP), and Upper Palaeolithic (30-10,000) sites in Italy and Europe. - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - DENPH - - - H2020-MSCA-IF-2016 - - - 752626 - - - - - HELSINGIN YLIOPISTO - - - EUR 169 728 - - - Behaviour, knowledge, policy. The philosophy of science perspective on the applications of the behavioural sciences in policymaking. - - - EUR 169 728 - - - Finland - - - Higher or Secondary Education Establishments - - The project addresses the problems emerging from the application of the behavioural sciences to policymaking. These applications refer to research in cognitive psychology, behavioural economics, decision theory and are - supposed to provide the knowledge necessary to make policy that is effective. The aim of the project is to analyse how the latest findings in the behavioural sciences are used in policy contexts, to address the challenges which this use provokes, as - well as to advance a novel approach to an analysis of behavioural sciences and policy, informed by philosophy of science. - - - 2020-07-15, Grant Agreement signed - - - 2018-07-16 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Finland - - - EPISTEMEBEHAVIOUR - - - H2020-MSCA-IF-2016 - - - 751791 - - - - - UNIVERSIDAD DE VALLADOLID - - - EUR 170 121,60 - - - Biological Valorization of Methane Emissions - - - EUR 170 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - This action aims to obtain new methanotroph strains able to transform methane into valuable user products, in particular the bio-polymer PHA and ectoine. This will contribute to couple the abatement of a gas with high - green-house power, to the production of useful chemicals and bio-consumables, which is in agreement with the objectives of H2020. - - 2019-09-17, ongoing project - - - 2017-09-18 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - CH4BioVal - - - H2020-MSCA-IF-2016 - - - 750126 - - - - - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - - - EUR 195 454,80 - - - Smart Optical Metamaterials: A route towards electro-tuneable fast-reversible self-assembly of nanoparticles at controlled electrochemical interfaces - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Futuristic smart optical applications belong to novel artificial materials comprising nanoscale building blocks, exhibiting extra-ordinary optical responses. Recent progress in nanotechnology has enabled developing such - optical metamaterials (OMMs) economically via controlled self-assembly of nanoparticles (NPs). Strikingly, a dense nanometre-thick layer of metallic NPs strongly reflects incident light like a ‘mirror’, whereas a sparse layer enacts a - near-transparent ‘window’. Thus OMMs could form a switchable mirror–window to minimize our energy needs by harvesting light. Besides tuneable-optics, dense OMMs could revolutionise sensing of trace-analytes for detecting threats to our health, - safety, and security. I aim to develop new means of dynamic control over resulting NP-layer architecture to make OMMs ‘smart’, for novel applications like fast-programmable mirrors, -tuneable optical-filters and -cavities. But achieving quick - alteration of NP architectures for fast-tuneable optical response is very challenging. Voltage-controlled assembly and disassembly of NPs at interfaces between liquid electrolyte and solid electrodes could be one efficient method. However, these - processes are often diffusion-limited, making OMMs slow to respond. This requires the desired systems to be confined, or miniaturized, by developing new schemes and custom-made architectures to ensure assembly/disassembly occurs within sub-second - timescales. To achieve this, I will engage novel electrode designs—patterned as rectangular-groove gratings, columnar structures, and flat transparent plates—where NPs can rearrange quickly on desired areas of the electrodes to either reflect or - transmit light. This research unites physical-chemistry with optics and nanotechnology. I will develop optimal designs of the systems, via modelling and simulations, and navigate experiments for prototype creation in collaborating laboratories of the - Imperial and overseas partners in France, Netherlands, and Germany. - - 2020-06-14, Grant Agreement signed - - - 2018-06-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - S-OMMs - - - H2020-MSCA-IF-2016 - - - 751763 - - - - - INSTITUT CURIE - - - EUR 173 076 - - - In vivo functions of nuclear envelope rupture and antiviral specialization in dendritic cells - - - EUR 173 076 - - - France - - - Research Organisations - - Dendritic cells (DCs) function at the interface between innate and adaptive immunity and have a crucial role in the induction of immune responses. The goal of this project is to uncover the in vivo functions of two novel - molecular mechanisms that were recently identified in vitro in DCs. DCs are rapidly activated when DNA is exposed to the cytosol, which can occur in viral infections. Recent work has revealed that DNA is also transiently accessible to the cytosol in - migrating DCs due to rupture of the nuclear envelope, and is detected by the cytosolic DNA sensor cGAS. In the first aim of this project we will investigate the immune consequences of nuclear envelope rupture in DCs in vivo. The second aim of this - project is to investigate antiviral specialization of DC subsets. Viral infection of DCs impairs their immune functions. Unpublished data has revealed that in humans, the CD141+ DC subset is constitutively resistant to a broad range of enveloped - viruses. Resistance was associated with the expression of the GTPase, RAB15. We will investigate the function of RAB15 in DC biology in vivo to study the division of antiviral labor among DC subsets. - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - DCBIO - - - H2020-MSCA-IF-2016 - - - 751735 - - - - - UNIVERSITAIR MEDISCH CENTRUM UTRECHT - BETH ISRAEL DEACONESS MEDICAL CENTER, INC NON PROFIT CORPORATION - - - EUR 242 929,80 - - - The Prelude to Psychosis: Brain network analysis in emerging schizophrenia - - - EUR 242 929,80 - - - Netherlands - United States - - - Higher or Secondary Education Establishments - Research Organisations - - Schizophrenia is a severe psychiatric disorder characterized by recurrent psychotic episodes that typically commence in early adulthood. There is consistent evidence for anatomical and functional brain abnormalities in - schizophrenia, but their timing is unclear. Changes in behavior and cognition precede the first psychotic episode by many years, suggesting that the underlying neurobiological process predates the onset of psychosis. Clarifying the neurobiology of - the pre-onset or ‘prodromal’ phase will facilitate the development of early intervention and prevention strategies for schizophrenia. I hypothesize that disruptions in the anatomical brain network, and associated disturbances in functional - integration among specialized neural circuits, drive changes in behavior and cognition in the prodromal phase. In this project, I have the opportunity to test my hypothesis in a unique sample of medication-naive adolescents and young adults with - early signs of impending psychosis, that are followed prospectively as they progress through the vulnerable prodromal period. This sample is collected as part of an ongoing NIMH-funded collaborative research program between a multidisciplinary - Harvard/MIT research team and the Shanghai Mental Health Center. Using network science as a mathematical framework, I propose to study brain network architecture in this sample of youths with early signs of impending psychosis, to assess how - disruptions in the brain’s network underlie prodromal symptoms and cognition, whether early neuroinflammation contributes to brain network deficits, and to test brain network metrics as early identifiers of emerging psychosis. - - 2020-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Netherlands - - - PRE-PSYCH - - - H2020-MSCA-IF-2016 - - - 749201 - - - - - THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS - - - EUR 195 454,80 - - - Inside Speakers' Corner. Late Medieval Italian Anchoresses in European Context. - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - "Voluntary reclusion was an ancient form of penitential religious life based on withdrawing into a tight space, either temporarily or forever. The particular phenomenon of urban reclusion which flourished in the 13th and 14th - centuries was a mainly female activity, need not be tied to a religious order, and seems to have been linked to the expansion of cities across Europe. It is an important indicator of female levels of religious participation and of their social role - since these women often acted as consultants and advisors to the wider community. This research project will thus improve our understanding of a phenomenon that characterized all of Latin Europe, as of the condition of medieval woman, while also - reshaping our image of the medieval city, to one scattered with cells. There is, currently, a great disparity in historiographical terms between Italy and the rest of the continent on this subject. Whereas some parts of Europe and of northern Italy - are relatively well researched, others are devoid of studies. The aim of this project is thus to verify whether – and if so, how and why – there was an Italian model of reclusion with characteristics different to those beyond the Alps; how recluses - related to the urban communities from which they withdrew and the extent to which this phenomenon was a way for medieval women to break the silence imposed by St Paul ("Women are to be silent in the churches. They are not permitted to speak", 1 - Corinthians 14:34); to exercise from and thanks to the cell a sort of power on the civil and ecclesiastical society; to break out of conventional, restricted roles of mother or wife or nun imposed by the medieval society, or more often a dignified - way of life for poor single women, for whom the lack of a dowry barred entry to a nunnery or marriage. The first step will thus be the construction of a prosopographical database of Italian anchoresses mapping the phenomenon, followed by a - comparative study of Italy in European context" - - 2019-09-10, ongoing project - - - 2017-09-11 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - InSpeCo - - - H2020-MSCA-IF-2016 - - - 751526 - - - - - UNIVERSITY OF DUNDEE - UNIVERSITY OF DUNDEE - - - EUR 1 687 500 - - - Mapping Cytokine Signalling Networks using Engineered Surrogate Ligands - - - EUR 1 687 500 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Cells use an intricate network of intracellular signalling molecules to translate environmental changes, sensed via surface receptors, into cellular responses. Despite their prominent role in regulating every aspect of life, - we lack a comprehensive understanding of how signalling networks convey extracellular information into specific bioactivities and fate decisions. To rationally manipulate cell fate, which could fundamentally change the way that we treat human - diseases, first we need a systematic understanding of how signalling is initiated and propagated inside the cell. I discovered that specificity of cytokine receptor signalling not only depends on cellular determinants such as receptor density and - endocytic trafficking, but can be systematically altered by modulating ligand binding parameters and receptor binding geometries. A fundamentally novel approach combining high-throughput flow cytometry and QMS with engineered cytokine surrogate - ligands able to fine-tune signalling responses will generate detailed maps of the signalling networks engaged by cytokines in time and space to unveil the mechanistic basis that allow a receptor to trigger different signal activation programs and - bioactivities in response to different ligands. By quantitatively characterizing the signalling programs activated by ligands, using state-of-the-art biochemical, biophysical, structural, genetic and fluorescence imaging techniques, I plan to - identify events critical for cellular decisions. By fully characterizing the intracellular signalling network hard-wired inside a cell and understanding its dynamic in response to environmental changes will we be able to comprehend and manipulate the - enormous functional plasticity exhibited by cells. TInsights generated will open new fields of investigation where engineered ligands prove indispensable to understand complex biological responses and greatly advance our understanding of cytokine - biology and human immunology in health and disease. - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - Cytokine Signalosome - - - ERC-2016-STG - - - 714680 - - - - - UNIVERSIDAD POLITECNICA DE CARTAGENA - - - EUR 170 121,60 - - - INvestigating SDN Programmability ImpRovING optical South- and North- bound Interfaces - - - EUR 170 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - Population needs for Internet connectivity rely on carrier networks currently challenged by the ever-increasing network complexity, traffic volume, and dynamicity. Software Defined Networking (SDN) has entered the networking - scene as an enabling technology that brings programmability to the network by decoupling the forwarding data-plane actions from the logic control-plane decisions through application programming interfaces. However, the variety of controllers - governing different network segments and interfaces for control and management endangers actual carrier-grade SDN deployments. - - 2020-02-29, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - INSPIRING-SNI - - - H2020-MSCA-IF-2016 - - - 750611 - - - - - QUEEN MARY UNIVERSITY OF LONDON - - - EUR 195 454,80 - - - Amplitudes and form factors via integrability - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Our theoretical description of natural phenomena is mostly limited to the regime where the interaction among fundamental particles is sufficiently weak, making the understanding of strongly-coupled gauge theories one of the - main challenges of current research in theoretical physics. This proposal aims to study the structure of form factors -- important off-shell generalizations of scattering amplitudes of great phenomenological relevance -- in the maximally - supersymmetric Yang-Mills theory at all values of the coupling. Importantly, the strong- and finite-coupling regimes are made accessible by the AdS/CFT correspondence and its integrable structure, respectively. The methods required to achieve the - goals of this proposal will extend in a non-trivial way the recent beautiful results in the related field of scattering amplitudes. In particular we plan to derive a precise correspondence between form factors and Wilson loops, to exploit this - picture to investigate the strong-coupling regime, and to extract finite-coupling predictions for form factors in the spirit of the recent, powerful OPE approach to scattering amplitudes. Finally we will also analyze the properties of form factors - under collinear factorization. - - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - AFFINITY - - - H2020-MSCA-IF-2016 - - - 749909 - - - - - UNIVERSITETET I BERGEN - - - EUR 196 400,40 - - - The Symbolism of the Body in Northern Europe. Cognitive Metaphors and Old Norse Myth from the Viking Age to Late Medieval Times - - - EUR 196 400,40 - - - Norway - - - Higher or Secondary Education Establishments - - The aim of the proposed research is to investigate the integrative function of bodily metaphors within the Old Norse Literature and Culture. The research will span the culturally important transition from pre-Christian culture - to the products of Christian literacy. Its starting point will be the mythic narratives connected with initiation and sacrifice, which have a foremost position in the pre-Christian religion and which are especially rich in the cognitive metaphors of - the human body. These myths and rituals exerted an influence as a pattern or model for the whole society, and provide thus an excellent tool for the understanding of its symbolic system and values. In the next step of the project the transition - towards Christianity will be explored and assessed, especially its reevaluation of cognitive metaphors of the body, with the aim to map the transformations of symbolism on the borders of two cultural and religious systems. This endeavour will provide - a completely new theory shedding new light on the production of meaning in culture and its reinterpretations. The research itself is to be naturally interdisciplinary, integrating religious studies, philology, cognitive linguistics, anthropology and - folkloristics. My previous research prepared me for this task to a certain degree, but knowledge exchange is needed to bring it to a completion, especially consultations with scholars and experts in the field of Old Norse Studies. All this can be - achieved by a 18 months research internship at the University in Bergen, which provides the best academic conditions for this project, supervised by prof. Jens Eike Schnall, and by a 6 month secondment in Reykjavík, at the University of Iceland and - at the Árni Magnússon Institute for Icelandic Studies. This project will apply innovative interdisciplinary approach to the topic and initiate a collaboration between Prague and Bergen and Prague and Reykjavík researchers in Old Norse religion. - - 2020-07-31, Grant Agreement signed - - - 2018-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Norway - - - SYMBODIN - - - H2020-MSCA-IF-2016 - - - 750379 - - - - - UNIVERSITY OF EAST ANGLIA - - - EUR 195 454,80 - - - Volcanoes: eruptive style, pre-eruptive evolution and risk - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - This project will use the compositions and crystal cargoes of erupted magmas to study pre-eruptive behaviour of magmatic systems. The aim is to understand their relationship to, and control on, periodicity and style of - volcanic eruptions to mitigate hazards and risks. To do this we will undertake detailed description of the whole-rock composition and mineral chemistry of volcanic rocks from active intra-plate and subduction-related volcanoes. New knowledge about - zircon behaviour will then be considered in the context of these well-constrained systems. - - 2019-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - VESPER - - - H2020-MSCA-IF-2016 - - - 749611 - - - - - FUNDACION PUBLICA ANDALUZA PARA LA INVESTIGACION DE MALAGA EN BIOMEDICINA Y SALUD - - - EUR 158 121,60 - - - Targeting the Endocannabinoid System within Islets of Langerhans to Protect against Immune Destruction. - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - Europe has the highest prevalence per capita of children with type 1 diabetes (T1D), an autoimmune disease with no cure that results in progressive destruction, and finally an absolute loss, of insulin-producing beta (β) cells - in islets of Langerhans in the pancreas. This means that patients require exogenous insulin administration for life. Additionally, prolonged uncontrolled blood glucose levels increase the risk of cardiovascular diseases, peripheral neuropathy, renal - failure and numerous infections. The endocannabinoid receptors (ECRs) CB1, CB2 and GPR55 are regulators of metabolism and immune action and are also present on β cells. Cannabidiol, a CB1 antagonist, reduced the incidence of T1D in mice by reducing - insulitis, thereby preserving β cell mass. Additionally, blockade of CB1 alters insulin secretion, increasing proliferation and autophagy in β cells. Importantly, β cell-specific CB1 knockout mice have no T-cell infiltration in islets when their - pancreas is challenged. Furthermore, activation of GPR55 and CB2 are reported to be beneficial in protecting from inflammation. In this project we intend to study the interaction of the ECRs and their potential synergy for protecting β cells from - insulitis. For this purpose, we will generate a non-obese diabetic (spontaneously develops autoimmune insulitis) β cell-specific CB1 knockout mouse, and use pharmacological approaches to enhance GPR55 and CB2 signalling to determine if the diabetic - condition can be prevented/ameliorated. We will assess β cell damage together with mitochondrial function, autophagy, and inflammatory responses in our mouse model and after pharmacological manipulation. Thus, this project proposes a new strategy, - not focusing on the immune system but on the role that β cells themselves play in modulating their own reactivity, for the development of new therapies for preventing and/or treating T1D. - - 2020-01-02, ongoing project - - - 2018-01-03 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - DIRECtA - - - H2020-MSCA-IF-2016 - - - 748749 - - - - - UNIVERSITA DEGLI STUDI DI TERAMO - - - EUR 180 277,20 - - - Exploring dry storage as an alternative biobanking strategy inspired by Nature - - - EUR 180 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - Biobanking under liquid nitrogen (LN) has satisfactory efficiency but it comes with many drawbacks (e.g. expensive, high carbon footprint, need dedicated facilities, trained personnel, and continuous monitoring and LN supply). - Searching Nature for alternatives, long-term preservation there is done by drying rather than freezing. To date, however, mammalian cells do not survive the drying process. Even so, if somatic cells genetic and epigenetic load is maintained, drying - can find an important role in biobanking, a fast growing global industry. We aim to elucidate the effects of drying on DNA structure and function, crucial aspects of long-term biobanking not investigated yet, using fibroblast as a model cell, and - combining advanced freezing and drying techniques with state-of-the-art Somatic Cell Nuclear Transfer (SCNT) and latest genomic technologies. The expected outcomes are definitive data on effects of drying on genomic stability/function, and possible - discovery of a protocol to protect the epi/genetic load during cell drying. The crossing between the Researcher’s scientific interest and experience in sperm biology, andrology, cryobiology and drying and the Supervisor’s expertise in embryology and - SCNT creates an attractive and very solid background for this proposal, with mutual benefit to both Host and Researcher. While strengthening the Supervisor’s laboratory with his expertise, the Researcher will enhance his creative potential and - further develop his interdisciplinary and communication skills by learning SCNT and whole genome analysis as well as mentoring students, participating in conferences, and communicating research results to targeted audiences (scientists, general - public, students, stakeholders, policymakers), thus enhancing his scientific profile. This proposal is the perfect stepping stone for the Researcher to become an independent scientist and an expert in desiccation for biobanking, while contributing a - competitive advantage to the Host. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - DRYSTORE - - - H2020-MSCA-IF-2016 - - - 749537 - - - - - ROYAL COLLEGE OF SURGEONS IN IRELAND - - - EUR 187 866 - - - Platelet tractions through the Glycoprotein (GP) GPIb receptor as a potential marker for platelet reactivity - - - EUR 187 866 - - - Ireland - - - Higher or Secondary Education Establishments - - Platelet-mediated thrombosis is a major cause of death and disability globally. Thrombosis occurs when platelets adhere and aggregate. In the arterial circulation initial platelet adhesion occurs when the platelet glycoprotein - (GP) I-IX-V receptor binds to von Willebrand Factor (vWF). Increased or decreased expression levels of GPIb are associated with increased risk for cardiovascular events and bleeding respectively. The expression of GPIb varies significantly among - healthy subjects. The proposed project aims to characterise the role of GPIb expression levels on traction forces and platelet reactivity. It therefore combines my significant expertise in cellular mechanobiology and traction force microscopy with - theclinical expertise of Prof Dermot Kenny’s group in platelet biology and the development of diagnostic assays for platelet function. A micropost array platform for high throughput, single cell, traction force measurements will be developed and - applied to understand the interaction between GPIb traction forces andplatelet reactivity, first in healthy donors and then in patients with cardiovascular disease receiving antiplatelet therapy. This platform could in the future be further exploited - for examining platelet function to further understand platelet cancer interactions, and for the innovation of refined diagnostics to assess platelet reactivity in individual patients. - - 2019-06-14, ongoing project - - - 2017-06-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Ireland - - - ThromboForce - - - H2020-MSCA-IF-2016 - - - 747586 - - - - - UNIVERSIDADE DO ALGARVE - - - EUR 148 635,60 - - - Optimisation of Tidal energy Converter Arrays - - - EUR 148 635,60 - - - Portugal - - - Higher or Secondary Education Establishments - - As technology readiness level of Tidal Energy Converters (TECs) increases, moving from prototype demonstration to commercialisation, research efforts are focusing on TEC arrays layout optimisation to reduce costs and become - competitive in comparison with other energy systems. Even though there are several prototypes of different scales that have been tested on the last years (mostly under controlled conditions) there is limited data on deployments in real conditions - which negatively affects the accurate formulation of constrained problems on array schemes resulting on incomplete layout optimisation models. This project aims to provide a significant contribution towards the understanding of (a) the effects of - TECs interactions with the environment; (b) the capabilities and limitations of common strategies used for the numerical modelling of TECs; and (c) how to mathematically formulate optimisation models to solve the TEC array layout problem considering - technical, socio-economic and environmental constraints. From the methodology point of view, constraint optimisation models will be mathematically formulated considering ocean energy protocols, data collected from in-field measurements of prototypes - tested in real environments and with surrogates built from validated numerical simulations. The outcomes of the project will contribute to improve common guidelines and standards for licensing tidal energy projects and de-risk financial investment. - The Experienced Researcher (ER) will emerge from the project with an in-depth knowledge of tidal stream energy, training in mathematical optimisation and on new skills in data collection, increased competence on numerical modelling, and strong skills - in research project management and coordination. This will grant him the capacity of achieving maturity as a researcher on ocean energy, a new emerging sector with great growth potential. - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Portugal - - - OpTiCA - - - H2020-MSCA-IF-2016 - - - 748747 - - - - - LEIBNIZ-INSTITUT FUER FESTKOERPER- UND WERKSTOFFFORSCHUNG DRESDEN E.V. - - - EUR 171 460,80 - - - Theoretical insides in endohedral metallofullerene based Self-Assembled Monolayers: Statics and Dynamics. - - - EUR 171 460,80 - - - Germany - - - Research Organisations - - Modeling of formation and properties self-assembled monolayer (SAM) is a very challenging task, especially if highly functional-ligands are concerned. It is true, for instance, in the case of endohedral metallofullerene (EMF) - based SAM - a promising single molecular magnet (SMM) grids in-making. Properties of such SMM grids would be a function of SAM architecture (attachment types and crowding effects) and inner-cluster dynamics under these geometrical constrains. - Electronic structure complexity of EMFs and structural mobility of ligands in SAMs brings a dual issue. On the one hand, a minimal level of theory to address the magnetic properties of the systems would require “complete active space”-quality - methods, yet the whole size (~10E3 atoms) of the system makes these computations hardly feasible and is limited so far to single molecules. On the other hand, while the system dynamic can be approached by less computationally demanding semiclassical - or even classical approaches, such methods are unable to give a reliable magneto-physics of the SMM unit. This project will offer a solution to this problem by extensive development of the multiscale methods (MSM), in which the whole system is - divided into the regions described with different levels of theory accordingly to its complexity. Developed protocols and schemes would be universals across SAM field and highly profitable for the SMM industry on a whole. - - 2019-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - SamSD - - - H2020-MSCA-IF-2016 - - - 748635 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 158 121,60 - - - Deciphering the role of oxylipins in the epigenetic mechanisms controlling plant immunization. - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - Reducing crop losses caused by pests and diseases is absolutely necessary to feed the increasing world population, but the use of pesticides increases the damage to the environment and contributes to climate change. As a - result, international entities such as the European Union are promoting the search for alternative strategies. Experts point to “plant immunization” or priming, as the safest and most effective approach to boost the endogenous plant immune system. - Unfortunately, deeper knowledge of the involved mechanisms is needed for its application in crop protection. In this context, epigenetic mechanisms and oxylipin pathways are involved in priming processes but their specific contribution as well as the - relationship between these two pathways has not yet been addressed. In order to fill this gap in our knowledge we propose an ambitious but feasible project that builds on solid and exciting preliminary results. We will use the unique genetic and - molecular tools available in the model plant Arabidopsis thaliana to analyse first the role of oxylipin natural compounds in different priming processes and then, study the relationship between both molecular pathways to delineate plant defence - mechanisms and priming. The synergistic interaction formed by the host group, world-leading in oxylipins research, and the applicant, an expert in epigenetics, guarantees the maximization of two way transfer of knowledge, training and networking - possibilities. Moreover, this action has a potentially remarkable impact and represents a key point in the applicant´s career complementing her current knowledge and expanding her skills. Taking these considerations together, the EPILIPIN project - offers a unique opportunity for the development of a research that perfectly fits the EU concerns and priorities of improving crop yields minimizing the impact of agriculture on the environment by exploring the use of natural compounds (oxylipins) to - trigger long term immunization (priming). - - 2020-01-15, ongoing project - - - 2018-01-16 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - EPILIPIN - - - H2020-MSCA-IF-2016 - - - 746136 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 170 121,60 - - - New DELLA-based biotechnological tools for sustainable Agriculture - - - EUR 170 121,60 - - - Spain - - - Research Organisations - - Since their discovery, the plant hormones gibberellins (GAs) and their inhibitors have become a widely used tool to improve very diverse agronomical aspects, such as the size and productivity of grasses, horticultural species - and ornamental plants. However, indiscriminate application of these compounds also provokes undesired secondary effects. For instance, GA application is used in agriculture to promote and synchronize fruit development, but it weakens the defense - mechanisms against pests. Therefore, there is a serious need to find new GA-related biotechnological tools that specifically improve certain agronomical traits without the lateral effects. Based on the deep knowledge generated about GA signaling in - the past 20 years with the help of our own lab, here we propose to (1) establish a method to generate plant varieties that specifically improve certain GA-related traits without the lateral effects; (2) search for compounds that specifically mimic - certain aspects of GA signaling; and (3) in conjunction with a Spanish biotech company, provide a well-trained academic scientist with the capacities needed to develop a professional career within industry-oriented biotechnological research. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - DELLATECH - - - H2020-MSCA-IF-2016 - - - 746396 - - - - - UNIVERSITE D'AIX MARSEILLE - - - EUR 108 172,50 - - - Systematic analysis of Pacific phytoplankton and islands regional effects - - - EUR 108 172,50 - - - France - - - Higher or Secondary Education Establishments - - "Phytoplankton, the tiny algae that fix carbon dioxide via photosynthesis, represent the base of the oceanic food chain and support essentially all life in the oceans. In the tropical Pacific, where phytoplankton biomass is - low, local nutrient enrichments near islands support ecosystems characterized by higher biomass and biodiversity. While this "island effect" has been known for 60 years, the vast majority of islands remain unstudied and impacts at the basin scale are - unknown. Additionally, little is known regarding changes in phytoplankton community structure despite implications for higher trophic levels. The SAPPHIRE project will elucidate the impact of islands on phytoplankton by conducting the first - systematic study of the island effect in the tropical Pacific from a suite of physical and biological satellite data. This project leverages the OUTPACE in situ 20°S transect that sampled phytoplankton community composition nearby several islands in - 2015 and the breakthrough satellite-based PHYSAT method that detects phytoplankton functional groups from space. Novel methods identifying and characterizing the island effect will be first developed in the OUTPACE region from in situ and satellite - data, then applied to the entire tropical Pacific using satellite data. The ultimate goals are to 1) quantify the impact of islands on phytoplankton and physics in the tropical Pacific and 2) classify the islands as a function of enrichment processes - and phytoplankton responses using cutting-edge machine learning techniques. SAPPHIRE provides a highly original perspective on marine ecological research by systematically conducting thousands of small-scale process studies over a large area, - effectively providing a large-scale assessment of a mesoscale process. This project will be an important step in my career development by establishing me as a leading scientist in the emerging field of multidisciplinary data-intensive oceanography in - Europe." - - 2019-05-23, Grant Agreement signed - - - 2018-02-24 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - France - - - SAPPHIRE - - - H2020-MSCA-IF-2016 - - - 746530 - - - - - UNIVERSITY COLLEGE LONDON - - - EUR 195 454,80 - - - Revisiting an ancient craft in a contested region: The analytical paradigm of prehistoric pottery from Cyprus - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - ReCyPot is a large-scale, interdisciplinary study of ancient ceramics from the region of Lapithos on the northern coast of Cyprus that addresses four different themes of cross-cultural and cross-regional significance: 1) - ancient technology, 2) ancient Mediterranean history and archaeology, 3) the restudy of older excavated material with new methods of analysis and interpretation and 4) the study of ancient artefacts from areas presently inaccessible to archaeological - and historical research. Integrating ceramic petrography and methods of chemical and microstructural analysis (including WD-XRF, NAA and SEM), this will be a thorough analytical study of ancient pottery, dated to the end of the third millennium and - the second millennium BC, the comparative analysis of contemporary pottery from the region, as well as ceramics from intervening periods in Lapithos. While the project deals with a specific region on the island of Cyprus, it can be used as an - exemplar for addressing broader, cross-cultural and methodological questions regarding the definition and recording of pottery traditions, how these are transformed and how modern archaeologists can perceive and study them. The project will attempt - to reconstruct the ancient pottery traditions of Lapithos and define those compositional and technological elements that form the Lapithos ceramic profile. Beyond the definition of regional ceramic traditions and elements of stability and change - through time, this project will consider environmental, technological, sociocultural and historical factors that must have had an impact on ceramic production, distribution and consumption. Pottery production will be integrated into its regional and - inter-regional socio-economic context, and provide an insight into the ancient society and history of the region, an integral part of the ancient Mediterranean. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ReCyPot - - - H2020-MSCA-IF-2016 - - - 747339 - - - - - UNIVERSITAET STUTTGART - - - EUR 159 460,80 - - - Direct cooling of dipolar molecules - - - EUR 159 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - Full quantum control of molecules has been an outstanding goal for decades. Cooling molecules provides a most promising answer to address this challenge. With recent progress in experimental quantum physics, such cooling is - finally within reach. The aim of this project is to demonstrate the novel technique of molecular laser cooling for a gas of barium monofluoride molecules. Realizing a cold gas of these dipolar molecules will pave the way for a large number of novel - and interdisciplinary applications ranging from few- and many-body physics to cold chemistry and tests of fundamental symmetries. The combination of this unique research project with the excellent environment for training, networking and research at - the University of Stuttgart will ideally prepare the applicant, Dr. Tim Langen, for a future career as an independent research group leader. - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Germany - - - coolDips - - - H2020-MSCA-IF-2016 - - - 746525 - - - - - UNIVERSITE DE GENEVE - - - EUR 265 840,20 - - - Quantum Kinetic Equations for Pre-thermal Light and Matter - - - EUR 265 840,20 - - - Switzerland - - - Higher or Secondary Education Establishments - - One of the research forefronts in quantum many body physics, is represented by the non-equilibrium dynamics of strongly - - 2021-02-27, Grant Agreement signed - - - 2018-02-28 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Switzerland - - - QUAKE4PRELIMAT - - - H2020-MSCA-IF-2016 - - - 745608 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 2 000 000 - - - Activity-dependent modulation of synapse identity - - - EUR 2 000 000 - - - France - France - - - Research Organisations - Research Organisations - - The mature brain results from the formation of precise networks between functionally and morphologically distinct types of neurons. A given neuron forms synapses with a limited number of partners and on precise subcellular - localizations. Understanding what controls this specificity is mandatory not only to understand brain functions but also the aetiology of synaptopathies such as autism spectrum disorders or schizophrenia. Various molecules define the identity of each - type of synapse. Furthermore, neuronal activity-dependent mechanisms sculpt and stabilize neuronal connectivity. I posit that neuronal activity controls the molecular identity of synapses and that this regulation occurs through mechanisms specific - for each neuronal population, thereby regulating synapse specificity. I focus on the olivocerebellar network, which is involved in motor control and also in cognitive processes. In this well-characterized circuit, two different excitatory inputs, the - climbing fibres and the parallel fibres converge on the same target, the cerebellar Purkinje cells, compete for their non-overlapping territory and possess distinct functional, morphological and molecular characteristics. Purkinje cells thus provide - an ideal model to study the molecular basis of synapse identity and its regulation. In the past years, I have developed new genetic tools to dissect the molecular characteristics of the olivocerebellar network at the neuron- and synapse–specific - levels. I propose to generate new mouse models to control neuronal activity, in vivo and during development, specifically in the two Purkinje cell excitatory afferents. Combining these tools, my objectives are to describe the molecular diversity of - synapses, show its control by neuronal activity, and characterize the molecular determinants of synapse identity. This study will bring a unifying view of the mechanisms controlling the development of a functional brain. - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - France - - - SynID - - - ERC-2016-COG - - - 724601 - - - - - THE UNIVERSITY OF LIVERPOOL - THE UNIVERSITY OF LIVERPOOL - - - EUR 1 668 418 - - - Beyond the Iron Curtain - - - EUR 1 668 418 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - As one of the largest carbon reservoirs in the Earth system, the ocean is central to understanding past, present and future fluctuations in atmospheric carbon dioxide. In this context, microscopic plants called phytoplankton - are key as they consume carbon dioxide during photosynthesis and transfer part of this carbon to the ocean’s interior and ultimately the lithosphere. The overall abundance of phytoplankton also forms the foundation of ocean food webs and drives the - richness of marine fisheries. - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - BYONIC - - - ERC-2016-COG - - - 724289 - - - - - UNIVERSITE PARIS-SUD - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - UNIVERSITAET REGENSBURG - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - UNIVERSITA DI PISA - CONSIGLIO NAZIONALE DELLE RICERCHE - UNIVERSITY OF LEEDS - TEMATYS - - - EUR 3 786 160 - - - Mid- and far-IR optoelectronic devices based on Bose-Einstein condensation - - - EUR 3 786 160 - - - France - France - Germany - Greece - Italy - Italy - United Kingdom - France - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Optoelectronic devices typically operate in the weak coupling regime between light and matter, for example in conventional lasers relying on population inversion to achieve optical gain. Recently there has been a surge of - interest in quantum systems operating instead in the strong coupling regime, when the coupling strength of the light-matter interaction is so strong that new states – cavity polaritons – are created, that are partially light, partially material - excitation. In semiconductors, exciton-polaritons have been the most widely studied type of strongly coupled system. Recently a new phenomenon has been realized exploiting intersubband transitions. The resulting excitations are called intersubband - polaritons, and they have two remarkable properties: (i) a bosonic character that is maintained up to high carrier densities since they are not restricted by the Mott transition limit; (ii) large Rabi splittings. Although the scientific community has - explored the basic science of intersubband polaritons, their potential for future and innovative optoelectronic devices has been entirely untapped. - - 2020-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.2.1."> - - - FETOPEN-01-2016-2017 - FET-Open research and innovation actions - - - RIA - Research and Innovation action - - - France - - - MIR-BOSE - - - H2020-FETOPEN-1-2016-2017 - - - 737017 - - - - - NATURAL HISTORY MUSEUM - - - EUR 183 454,80 - - - GOethite in Supergene Systems: ANalysing trace element substitution goethite and related iron oxides and oxyhydroxides. - - - EUR 183 454,80 - - - United Kingdom - - - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - The GOSSAN project will provide a full and accurate study on the geochemical, morphological and structural composition of iron oxides and oxyhydroxide compounds, The attention will be focalized on goethite in different types - of Supergene Ore deposits (SOD). More precisely, it is aimed to investigate the concentration, structural position and cationic exchange and economic potential of goethite as an unconventional source of “Critical Elements” (CE). - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - GOSSAN - - - H2020-MSCA-IF-2016 - - - 751103 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 173 076 - - - New photoswitchable materials based on electron transfer process - - - EUR 173 076 - - - France - - - Research Organisations - - Design and synthesis of molecular materials whose physical properties can be controlled by external stimuli are of the most advanced research interests. In this project we aim to synthesize and study in-depth a family of - molecular compounds with adjustable electronic properties based on an intramolecular electron transfer (ET) mechanism. The ET phenomenon defines two stable states that can be controlled by temperature, light, electric field, pressure or a chemical - stimulus and can be used to design new molecular switches. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - ETSMM - - - H2020-MSCA-IF-2016 - - - 745696 - - - - - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE - - - EUR 187 419,60 - - - Nanoscale Earth Abundant Catalysts for Hydrosilylation of Alkenes and Industrial applications - - - EUR 187 419,60 - - - Switzerland - - - Higher or Secondary Education Establishments - - The hydrosilylation of alkenes represents one of the largest applications of homogeneous catalysis on an industrial scale, and currently platinum-based catalysts are used in the industries which are expensive. Although - homogeneous Earth abundant metal catalysts have been developed, they are not suitable for large-scale industrial applications. Hence, I will develop novel, inexpensive, and Earth-Abundant supported base metal nano-catalysts for the hydrosilylation of - alkenes to produce linear alkylsilanes including Si-polymers, which are important products in the chemicals, materials, and pharmaceutical industries. The proposed catalysts are heterogeneous, easily separable from the reaction mixture, and reusable. - To achieve this aim, supported Fe, Co, Ni and Mn nano-catalysts will be prepared, characterized, and tested for catalysis. Priority will be given to iron-based catalysts. The most effective nano-catalysts will be applied to the production of - silicon-polymers/materials. Altogether, the acquired knowledge from this research project will help the scientific and chemical community to design cheap nano-catalysts for hydrosilylation. This project will be carried out in Laboratory of Inorganic - Synthesis and Catalysis (LSCI) at EPFL under the supervision of Prof. Xile Hu. This project will allow me to develop my knowledge and skills in the field of nanomaterials and heterogeneous catalysis in order to enhance my future as an independent - researcher in the area of catalysis for advanced organic synthesis and energy applications. - - 2019-06-30, Grant Agreement terminated - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Switzerland - - - NEACHA - - - H2020-MSCA-IF-2016 - - - 745083 - - - - - UNIVERSITEIT LEIDEN - UNIVERSITEIT LEIDEN - - - EUR 2 000 000 - - - Understanding and Controlling Glycosylation Reactions - - - EUR 2 000 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - This proposal aims to understand and control glycosylation reactions. In a glycosylation reaction a “donor” glycoside and an “acceptor” (the nucleophile) are united to form an oligosaccharide. Although it is the central - reaction in carbohydrate chemistry, our understanding of this reaction, in terms of stereoselectivity and productivity is still limited. The structural variation in the building blocks leads to a complex continuum of SN2-SN1 mechanisms that operates - and it is currently impossible to predict where in the continuum the reaction exactly takes place. This proposal provides fundamental insight into the outcome of glycosylations by studying both the activated donor glycoside and the acceptor - nucleophile. Activation of a donor glycoside leads to different reactive intermediates, covalent anomeric species (most often triflates) and oxocarbenium ion-like species. The relative reactivity of these species is quantified to generate novel - reactivity charts. The covalent species are studied by innovative competition experiments, kinetic studies and NMR spectroscopy. The (fleeting) oxocarbenium ion-like intermediates are probed by a computational approach and by “super-acid NMR” studies - in which stable glycosyl cations are generated and studied in super-acid media. The reactivity of glycosyl acceptors is systematically studied in a set of SN2 or SN1-type glycosylations. Using kinetic studies and competition reactions charts of - acceptor nucleophilicity are compiled. The reactivity of the donors and acceptors is matched using a family of tailor made “reactivity modulators”, spanning a broad reactivity window bridging the reactivity gap between the building blocks leading to - predictable glycosylations. The developed methodology is employed in automated solid phase syntheses of libraries of oligosaccharides featuring multiple cis-glycosidic linkages. The proposal is a major step forward in the development of a general - glycosylation procedure. - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - GLYCONTROL - - - ERC-2016-COG - - - 726072 - - - - - UNIVERSITEIT LEIDEN - NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU - TECHNISCHE UNIVERSITEIT DELFT - INSTITUT POLYTECHNIQUE DE GRENOBLE - CRANFIELD UNIVERSITY - ASTON UNIVERSITY - LINKOPINGS UNIVERSITET - - - EUR 3 995 643,24 - - - Circular European Economy Innovative Training Network - - - EUR 3 995 643,24 - - - Netherlands - Norway - Netherlands - France - United Kingdom - United Kingdom - Sweden - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Circ€uit – the Circular European Economy Innovative Training Network - creates a cohort of future leaders in research, policy & business through its innovative training programme focused on the Circular Economy. Circular - business models, based on leasing or providing functionality rather than products, often called Product Services Systems, are widely seen as a way how business can create sustainable jobs and growth. The Ellen MacArthur Foundation (EMF) and McKinsey - calculated that circular business will create billions of value. This opportunity has become an important development area for researchers engaged in the sustainability, engineering and design and business fields. - - - 2020-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2016 - Innovative Training Networks - - - MSCA-ITN-ETN - European Training Networks - - - Netherlands - - - CircEuit - - - H2020-MSCA-ITN-2016 - - - 721909 - - - - - UNIVERSITEIT UTRECHT - UNIVERSITEIT UTRECHT - - - EUR 1 499 902,50 - - - Dynamic Urban Environmental Exposures on Depression and Suicide - - - EUR 1 499 902,50 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - 19% of the Dutch population suffer from depression and people affected by depression have a significantly higher suicide risk. Although the World Health Organization attributes modifiable environmental factors including urban - environments (i.e. the built, natural and social environments) to health outcomes, they are largely disregarded as either stressors or buffers in scientific debates on depression and suicide. A limitation of current studies is that urban - environmental features are often restricted to the neighbourhoods within which people live. This may result in incorrect conclusions about health-influencing factors and inappropriate policies. Human life ultimately unfolds over space-time; people - are exposed to multiple urban environments not only during daily life but also over the course of their lives. It is this, not yet assessed spatiotemporal interplay of urban exposures that might revolutionize health assessments. - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Netherlands - - - NEEDS - - - ERC-2016-STG - - - 714993 - - - - - KATHOLIEKE UNIVERSITEIT LEUVEN - - - EUR 172 800 - - - Transnational meanings and makings of class: Polish labour, capital and the state - - - EUR 172 800 - - - Belgium - - - Higher or Secondary Education Establishments - - Class, as a leading category that explains unequal social relations between labour and capital, emerged out of the context of a national state framework. This research examines how class is made and imagined in instances in - which transnational processes of global capitalism release both capital and labour from the confines of a single nation state, and what remains of the nation state’s role as the guardian of particular class interests and in managing change. The - answer will be provided by a multi-sited ethnographic analysis of posted work, one of the flagship European Union projects which involves the transnational subcontracting of foreign labour for short-term projects under the provision of service. The - analysis will be conducted from the perspective of Polish workers posted to Belgium, their direct employers and the Polish state as the leading European state who posts labour abroad. By bringing to the fore the transnationally and culturally - sensitive investigation of class, the research will help to understand current economic situation and power struggles, and to gauge the practical and political possibilities for action towards a more just and equal European society, including - providing an informed basis on which to create posted work regulations, currently under the debate by the European Commission. At the theoretical level, the research will offer a fruitful cross-fertilization, whereby ethnographically sensitive, - anthropological inquiry will inform industrial relations research and help to reconceptualize class in the transnational era. The action will further my academic development towards acquiring a professorship position and will open up collaborative - possibilities on multi-disciplinary projects related to mobility and European transformations with Interculturalism, Migration and Minorities Research Centre at KU Leuven. - - 2019-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Belgium - - - TRANSCLASS - - - H2020-MSCA-IF-2016 - - - 753438 - - - - - CONSIGLIO NAZIONALE DELLE RICERCHE - - - EUR 168 277,20 - - - Modern Geospatial Practices for Ancient Movement Praxis - - - EUR 168 277,20 - - - Italy - - - Research Organisations - - Ancient roads cross-culturally reflect motivations and needs behind social, economic, political and religious relations of past societies; they imposed spatial order on agricultural production, enabled transportation of - bulk-goods, mediated hegemonic power, and facilitated urban fabric. Everyday actions of past individuals must have had contributed to the formation of roads. And, in return roads must have had sustained individual (and societal) connectivity. - Therefore, considered not only as the container of action, but also the action itself, the road has much more to say on the ancient movement praxis. - - - 2019-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - GeoMOP - - - H2020-MSCA-IF-2016 - - - 747493 - - - - - KOBENHAVNS UNIVERSITET - - - EUR 200 194,80 - - - Sounds Delicious: A historical anthropology of listening and sound in Danish and French cooking - - - EUR 200 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - The Sounds Delicious project investigates how sound and listening function in different culinary traditions in Denmark and France. The project aims to construct a new interdisciplinary dialogue between Sound Studies and Food - Studies that will enrich how we study everyday cooking processes and the gustatory. This study questions how we construct cultural histories of cooking. I suggest that dominant research paradigms based on alphanumeric and visual epistemic practices - (words, images, measurements) are insufficient for fully understanding the particular components and choreography of a cook’s practice—and what cooking relates about personal histories and larger social and cultural tendencies. In adopting an aural - perspective of the kitchen, I engage alternative methods of perceiving evidence, and I revisit approaches of documentation, analysis and communication of the everyday. In this project sound and sonic practices are both research object and research - method—both matter and medium. Sound is used to trace, analyse, even reenact different performances of cooking. I will establish a new corpus of examples documenting sound and aural perception in Danish and French kitchens between the 19th and 21st - centuries. In working with a varied set of historical and anthropological tools, I will not only identify sounds in cooking, but introduce performances of cooking in relation to other histories of sonic and sensory knowing. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - Sounds Delicious - - - H2020-MSCA-IF-2016 - - - 753565 - - - - - THE UNIVERSITY OF EDINBURGH - - - EUR 183 454,80 - - - Birthing Abolition: Reproduction and the Gradual End of Slavery in Brazil - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - BIRTHBRAZIL is an interdisciplinary project that will analyze how enslaved women’s reproductive trends and practices shaped the gradual abolition of slavery in the middle to large plantation holdings of Rio de Janeiro, Brazil - from 1850 (the definitive end of the country’s slave trade) to final abolition in 1888. The project aims to contend that the struggle to end slavery was intimately entangled not only with elite understandings of slave reproduction but also with - enslaved women’s own agency. To do so, it examines demographic trends among the enslaved population, elite views of enslaved women’s reproduction, and enslaved women’s own reproductive practices and agency. Like most Atlantic slave societies, the - Brazilian slave population was reproduced through imports and not natural growth. Historians have argued that for 19th-century Rio de Janeiro state, harsh labour regimes and disease caused negative growth rates, dismissing the idea of “reproductive - resistance”—the female enslaved practices of abortion and infanticide as purposeful attacks on the institution of slavery—popular in theories on Caribbean and US slavery. While enslaved women’s fertility control may not have caused negative - population growth in 19th-century Rio de Janeiro state, BIRTHBRAZIL hypothesizes that enslaved women’s practices of fertility control played an important symbolic role in how elites understood and approached slavery itself. The findings of - BIRTHBRAZIL are expected to demonstrate that enslaved women’s fertility control, both real and imagined, created the opportunity for abolitionists to implement the legal framework that abolished slavery. In doing so, the project provides historical - background to current-day debates on reproductive rights, women’s health, and gender equality. The results will be disseminated through an academic monograph, peer-reviewed open-access publications, a website, an international conference, public - history blogs, and a series of community lectures. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - BIRTHBRAZIL - - - H2020-MSCA-IF-2016 - - - 747374 - - - - - KOBENHAVNS UNIVERSITET - - - EUR 212 194,80 - - - Molecular understanding of metabolic complexes: Towards engineering the next generation of synthetic biosystems - - - EUR 212 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - Why most plant natural products escape industrial production? So far, synthesis of many of these high-value compounds in microbes is simply based on putting together all the players in a pathway. Nevertheless, to produce its - stunning chemical diversity, nature uses much more elaborate biosynthetic networks, frequently involving the formation of macromolecular assemblies termed metabolons. These complexes utilize dynamic interactions and partner exchange to produce the - desired compounds in a coordinated fashion. To take my biotechnological expertise one step further, I will study the dynamic mechanisms that rule the assembly and regulation of metabolons and use this knowledge to reshape the way microbial production - platforms are engineered. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - METABOLON - - - H2020-MSCA-IF-2016 - - - 752619 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 171 792,60 - - - Ultra-robust, flexible organic sensors for application in lactic acid sensing and selective biosensing - - - EUR 171 792,60 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The overall objective of “Robust OTFT sensors” is to apply Dr. Nikolka’s expertise in material science and organic electronics to the field of organic sensors. The aim of the specific project is to explore the use of state-of - the art conjugated polymers as a platform for flexible, low-cost lactic acid sensors and biosensors. Dr. Nikolka will therefore spend time in Prof. Zhenan Bao’s group (Stanford University), which is world leading in the areas of electronic-human - interfaces, e-skin and biological sensing technologies. In Prof. Bao’s group, he will learn the experimental techniques required for work on (bio-) sensors including microfluidics, flow-cell setups or the functionalization of surfaces. To ensure a - successful project outcome, Dr. Nikolka will build on his previous work and achievements, such as the discovery of high performance, disorder free polymers (Venkateshvaran*, Nikolka* et al., Nature, 2014) or the demonstration of high operational and - environmental stability of high-mobility conjugated polymer through the use of molecular additives (Nikolka et al., Nature Materials, in 2nd stage review). The project is aimed at providing Dr. Nikolka with the techniques and tools to grow as an - independent researcher which he will be able to demonstrate during the return phase by combining novel sensors designs with printing techniques pioneered at Cambridge University. “Robust OTFT sensors” will furthermore enable Dr. Nikolka to profit - from training and educational programs and allow him to gain essential skills in project management, leadership and financial independency. Finally, it is the goal of the project to create a strong international collaboration between the outgoing and - return host laboratories and connect expertise in sensing (Stanford) with the expertise in printed organic semiconductors (Cambridge). This work could lead towards various low-cost sensors for biomedical or lab-on-a-chip applications having a direct - and profound impact on society. - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - Robust OTFT sensors - - - H2020-MSCA-IF-2016 - - - 747461 - - - - - KOBENHAVNS UNIVERSITET - - - EUR 200 194,80 - - - Specialised plant cell types via developmentally-controlled gene knockouts: a key step towards fully customised plants - - - EUR 200 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - A goal of plant engineering is to produce valuable resources from CO2 and solar energy while exploiting the natural advantages of plants as production platforms. Plants have highly specialised cell types and sophisticated - development programs, resulting in specialist producer cells that are supported by non-producer parts. Plants are the only organisms that combine autotrophy and extensive multicellular differentiation, yet current engineering strategies fail to fully - exploit the potential advantages of plants as chemical production systems. This action proposes to develop and demonstrate a crucial technical advance in plant engineering: developmentally-programmed gene knock-outs in specialised cell types. - - 2020-02-29, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - GREEN-SPECIALISTS - - - H2020-MSCA-IF-2016 - - - 752430 - - - - - TECHNISCHE UNIVERSITAET MUENCHEN - - - EUR 159 460,80 - - - Dissipative Self-Assembly: A powerful but unexplored tool to create temporary supramolecular hydrogels - - - EUR 159 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - The aim of this study is to develop molecular temporary hydrogels coupled to an energy dissipating chemical reaction (DisMolGels). Until now, most molecular self-assembled materials operate close to thermodynamic equilibrium, - under static conditions, and are thus far from the interesting features biological living “materials” display. Biological materials are thermodynamically open and are kept far from equilibrium by a constant input of energy. This mode of - self-assembly, one of the requirements of life, is referred to as dissipative or dynamic self-assembly. For this project I will focus on the recreation of part of such dissipative processes, and translating them to our current static hydrogel - materials. With that, dynamic hydrogels with entirely new properties, most prominently their tunable lifetime and stiffness, will be developed. To do so, chemical fuels will be used as energy input and simple synthetic peptide derivatives will be - constitute the self-assembling building blocks. - - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - DisMolGels - - - H2020-MSCA-IF-2016 - - - 747007 - - - - - ISRAEL NATIONAL MUSEUM OF SCIENCE, TECHNOLOGY AND SPACE DANIEL AND MATILDE RECANATI CENTER - MIGAL GALILEE RESEARCH INSTITUTE LTD - WEIZMANN INSTITUTE OF SCIENCE - Bloomfield Science Museum Jerusalem (BSMJ) - THE HEBREW UNIVERSITY OF JERUSALEM - TEL AVIV UNIVERSITY - SAMI SHAMOON COLLEGE OF ENGINEERING(R.A.) FRIENDLY SOCIETY - UNIVERSITY OF HAIFA - THE OPEN UNIVERSITY* - BAR ILAN UNIVERSITY - ISRAEL OCEANOGRAPHIC AND LIMNOLOGICAL RESEARCH LIMITED - ORANIM ACADEMIC COLLEGE OF EDUCATION - THE KIBBUTZ MOVEMENT - AL-QASEMI ACADEMY ASSOCIATION - INTERDISCIPLINARY CENTER (IDC) HERZLIYA - - - EUR 300 000 - - - Reaserchers' Night Project 2016-2017 in Israel - - - EUR 870 025 - - - Israel - Israel - Israel - Israel - Israel - Israel - Israel - Israel - Israel - Israel - Israel - Israel - Israel - Israel - - - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Other - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Following previous TEN years of successful implementation of European Researchers' Night in Israel we will have: - - 2018-01-31, closed project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.5."> - - - MSCA-NIGHT-2016 - European Researchers' Night - - - CSA - Coordination and support action - - - Israel - - - ERNI2016 - - - H2020-MSCA-NIGHT-2016 - - - 721875 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 183 454,80 - - - G-Quadruplex-associated proteins (QAPs) and their role in transcriptional regulation - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - In the human genome, many G-rich sequences have the potential to form 4-stranded non-canonical secondary structures known as G-quadruplexes (G4s). G4 structures have been visualized in nuclei by immunofluorescence and mapped - genome-wide to regulatory chromatin regions linked to elevated transcription using G4 chromatin immunoprecipitation and high-throughput sequencing (G4 ChIP-seq). G4s are implicated in gene regulation, DNA replication and genome instability, yet - little is known about their protein interaction partners or role in regulating genome activity. - - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - QAPs - - - H2020-MSCA-IF-2016 - - - 747297 - - - - - UNIVERSITY OF YORK - - - EUR 251 857,80 - - - African Sky Forests: services, threats and management recommendations - - - EUR 251 857,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Tropical montane forests (TMF) are biodiversity rich and unique ecosystems which provide water to tens of millions of people, among other services such as firewood, medicinal plants, hazard prevention, climate modulation and - carbon sequestration. However, TMF remains understudied and over-exploited, particularly in Africa. Predicted climatic changes and trends in population growth will negatively affect the ecological functioning and ecosystem service delivery of these - already fragile ecosystems. Therefore, there is an urgent need to better understand these ecosystems and use that information to inform management. - - 2020-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - AFRI-SKYFOR - - - H2020-MSCA-IF-2016 - - - 743569 - - - - - FUNDACION DONOSTIA INTERNATIONAL PHYSICS CENTER - - - EUR 158 121,60 - - - Photochemistry and radiolabelling of gold(III) anticancer prodrugs - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - The use of light to activate anticancer prodrugs is nowadays a reality in clinics around the world. Photodynamic therapy is an effective treatment for the localised destruction of cancer cells in a range of tissues and organs. - Triggering the antiproliferative activity of chemotherapy agents with spatial and temporal control offers the advantage of reducing side effects and resistance. On the bases of the great success of metal-based drugs (e.g. cisplatin and its - derivatives), photoactivatable metal complexes have been investigated for their potential in light-activated therapy. This promising class of molecules is characterised by outstanding photophysical and photochemical features, which can result in - novel cytotoxicity mechanisms. Among transition metals, gold has shown promising anticancer features, however no attempt to exploit Au photochemistry for medicinal use has been reported yet. - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - PhoRAu - - - H2020-MSCA-IF-2016 - - - 746976 - - - - - LUNDS UNIVERSITET - - - EUR 173 857,20 - - - Addressing metalloenzymes for clean energy production with advanced embedding schemes andquantum mechanical methods - - - EUR 173 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - The proposed project aims to develop and apply quantum mechanical (QM) methods targeted at metalloenzymes, for which the methods in use today often fail. The failures are caused by inaccuracies in either 1) the underlying - protein structures, 2) the employed QM method or 3) the embedding method that describes electrostatic interactions between the protein environment and the active site (i.e. metal and its nearest ligands). The MetEmbed project addresses 1), 2) and 3) - with hydrogenases and polysaccharide monooxygenases (PMOs) as target enzymes. Hydrogenases mediate the reversible conversion of dihydrogen into hydride ions and protons, while PMOs have shown great potential for biofuel production. The overall - objective is to investigate the reaction and spin-state energetics for key intermediates in the two proteins' catalytic cycles. To ensure that the underlying structures are accurate, extensive molecular dynamics (MD) simulations with tailored force - fields and QM/MM methods will be employed. The adequacy of the QM methods will be ensured by using accurate, multireference QM methods that are known to be well-suited for transition metal systems. Two new multireference QM methods will be applied, - namely a multiconfigurational density functional theory hybrid and the density matrix renormalization group method. These methods have high potential for metalloenzymes, but have until now only found little use in this area. To address the effect of - the protein electrostatics, an accurate embedding scheme that, contrary to most QM/MM methods, includes the polarization of the environment will be used. The combination of 1) accurate structures, 2) accurate QM methods and 3) polarizable embedding - schemes is unprecedented for metalloenzymes. The MetEmbed project will thus predict energetics with a new level of confidence for two systems with high potential in the areas of energy efficiency and low-carbon energy production; both central parts - of the HORIZON2020 program. - - 2020-07-31, Grant Agreement signed - - - 2018-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - MetEmbed - - - H2020-MSCA-IF-2016 - - - 745967 - - - - - KOBENHAVNS UNIVERSITET - - - EUR 200 194,80 - - - Chromatin Study of DNA Double Strand Breaks - - - EUR 200 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - In stark contrast to common belief, cellular DNA is not de facto safe as it constantly encounters numerous perils. To keep chromosomal DNA intact and to prevent the onset of pathological conditions, such as cancer and - premature ageing, which are driven by DNA damage-induced genomic instability, life has evolved appropriate protective mechanisms, collectively referred to as the DNA Damage Response (DDR). A vital branch of the DDR is the response to DNA - double-strand breaks (DSBs), arguably the most cytotoxic and mutagenic lesions. DSBs lead to the modification of their local chromatin environment to allow scaffolding of downstream protein factories, comprised of signalling, chromatin remodelling - and DNA repair proteins. These DSB processing factories assemble in the context of chromatinised DNA, making chromatin architecture crucial for DSB restoration. Though our understanding of how chromatin status affects the DSB response has - significantly progressed in recent years, we are only starting to identify factors regulating this intricate interplay. Moreover, current ways to induce DSB result in random, heterogeneous DNA damage, therefore not allowing the study of the DSB - response in a specific chromatin compartment. In order to overcome this technical hurdle and to identify new regulators of DSB signalling and repair, I will use a powerful new method, combining the generation of limited, well-distributed DSBs, - exclusively located in either euchromatin or heterochromatin, with specific purification of DSB-containing chromatin protein-complexes. Subsequently, I will select, validate and functionally characterise novel factors that have not yet been - implicated in the DSB response, but behave similarly to known DSB-related proteins. By performing this multidisciplinary project, I will obtain new scientific and transferrable skills, thus taking a huge step towards true scientific independence and - better career opportunities. - - 2019-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - ChroSoDSB - - - H2020-MSCA-IF-2016 - - - 744866 - - - - - FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS - - - EUR 152 653,20 - - - European Frontiers: Rural Spaces and Expanding States - - - EUR 152 653,20 - - - Greece - - - Research Organisations - Zinovia Papatheodorou - Tel.: +30 2810 391522 - Fax: +30 2810 391555 - - Frontiers are dynamic zones of resistance and negotiation where local actors respond to the political/economic fluctuations of expanding states. Research on Europe’s frontier zones in the historic past has immediate relevance - to the modern economic and political landscape, where the expansion of transnational markets is creating new dynamic frontier zones. Yet due to the typical top-down approach employed by archaeologists and historians, the local experience of living in - a frontier has been largely overlooked. EUROFRONT adopts an innovative four-field methodology (archaeology, history, geomatics, and ethnography) to investigate two European frontiers in Crete and Dalmatia. Rich datasets will be developed for each - region, synthesizing archaeological data, archival materials (e.g. tax registers and cadastral maps), paleoclimate data, and modern oral histories about villages in the regions. Advanced geospatial analyses will be used to detect patterns in - population movement, settlement distribution, network connection, and agricultural production. During the project, the researcher will be trained in cutting-edge geomatics technologies, and the skills and knowledge she gains will enhance her - reputation as a leading scholar of Early Modern archaeology and history in Europe. Results of the study will provide insight into how frontier communities are shaped by the process of state expansion from an economical, social, political, and - environmental perspective. Project dissemination will prioritize publication of the raw data, training other scholars, and sparking an international dialogue about frontier zones that transects geographical and temporal boundaries. The project - website and interactive online GIS will be critical deliverables that not only promote the study of frontiers but also give voice to the local experience through publication of maps, photographs, and interviews with local residents. - - 2019-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Greece - - - EUROFRONT - - - H2020-MSCA-IF-2016 - - - 750483 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - - - EUR 201 514,50 - - - The History Play and the British Enlightenment, 1750-1815 - - - EUR 201 514,50 - - - Ireland - - - Higher or Secondary Education Establishments - - The aim of this Fellowship is for the researcher, Dr David O’Shaughnessy, to develop the professional prowess, advanced training, high-impact dissemination, and practical experience commensurate with a leading independent - researcher in the EU. The researcher will be based for 15 months at the Huntington Library, California (HL) supervised by Professor Kevin Gilmartin and for 12 months at the School of English, Trinity College Dublin (TCD) supervised by Dr Aileen - Douglas. Research training will be implemented through an interdisciplinary project investigating the importance of the history play to the discussion and dissemination of Enlightenment ideas in the two main London theatres of the eighteenth century, - Covent Garden and Drury Lane, 1750-1815. The key output will be the first monograph to be written on the eighteenth-century history play but the project will also communicate knowledge to a public audience through appropriate activities. On the - outgoing phase of the Fellowship, the researcher will access expertise, advanced training, mentoring as well as having access to the Larpent Collection of theatre manuscripts at the HL, the most important archive in the world for the study of - eighteenth-century theatre. Due to its unique archive holdings, the HL is the only institution in the world that can host this project; it also has collaborative relationships with Caltech and the University of Southern California (USC) which will - benefit the research in significant ways. In TCD the researcher will be given the opportunity to embed his new knowledge through undergraduate and postgraduate teaching, conferences and a symposium, and continued research. The resources of the host - institutions will facilitate development of an interdisciplinary and international academic network as well as career-mentoring. The Fellowship will establish the researcher firmly at the centre of eighteenth-century theatre studies and position him - for a successful ERC Consolidator application. - - 2019-08-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Ireland - - - HISTPLAY - - - H2020-MSCA-IF-2016 - - - 745896 - - - - - USTAV EXPERIMENTALNI BOTANIKY AV CR - - - EUR 154 720,80 - - - Widening gene pool of bread wheat by hybridization with Aegilops biuncialis supported by advanced genetic and chromosome genomic approaches - - - EUR 154 720,80 - - - Czech Republic - - - Research Organisations - - The widening of gene pool of bread wheat (Triticum aestivum) by employing its wild relatives as donors of new alleles and genes will ensure the ability of wheat to sustain yield quality and quantity under adverse environmental - conditions. Species from genus Aegilops represent a rich source of agronomically important traits, such as leaf rust resistance, grain nutritional quality and abiotic stress tolerance. To date, the utilization of wild genetic diversity has been - hampered by low throughput of methods used to select introgression lines and the lack of knowledge on the genomes of wild relatives. - - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Czech Republic - - - AEGILWHEAT - - - H2020-MSCA-IF-2016 - - - 746253 - - - - - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - - - EUR 195 454,80 - - - A Catalytic Method to Form Carbon–Carbon Bonds by Coupling Two Carbon–Fluorine Bonds. - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The aim of the fellowship is to pioneer a synthetic method to form carbon–carbon bonds from the coupling of two carbon–fluorine bonds. This method will result in new routes to fluorinated biaryls, organic molecules that are - used in materials science or as the active ingredient in pharmaceuticals and agrochemicals. It will open up new pathways to using inexpensive and environmentally persistent fluorocarbons in synthesis. - - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - FLUOROCROSS - - - H2020-MSCA-IF-2016 - - - 745806 - - - - - DEMOCRITUS UNIVERSITY OF THRACE - - - EUR 150 932,10 - - - Proposal title GREEce: modeliNg of the FOREst SEctor EcoNomy - - - EUR 150 932,10 - - - Greece - - - Higher or Secondary Education Establishments - - The economic role of the forest sector in Greece is a neglected field of academic inquiry. Studies of the markets for Greek forest products, are few and far between. This reflects a general lack of investment in the forest - sector of the country. An example of this is that the last national forest census was carried out in 1992. Meanwhile, the economic crisis that has plagued the country since 2008 has made matters worse, not only in terms of funds to study the sector - but also in terms of environmental outcomes. For instance, as a result of increasing poverty levels, many people have resorted to the use of fuelwood to satisfy their energy needs. This may seem like a good thing, in light of the Renewables - Directive's targets for renewable energy adoption. In reality, the switch to fuelwood has led to a severe increase in illegal logging. Despite the numerous and frequent media reports, scientific evidence of this is lacking. - - 2020-06-30, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-CAR - CAR – Career Restart panel - - - Greece - - - GREEN FORESEEN - - - H2020-MSCA-IF-2016 - - - 743900 - - - - - JYVASKYLAN YLIOPISTO - JYVASKYLAN YLIOPISTO - - - EUR 1 248 560 - - - Geometry of Metric groups - - - EUR 1 248 560 - - - Finland - Finland - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - What are the best trajectories to park a truck with several trailers? - - 2022-07-31, ongoing project - - - 2017-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Finland - - - GeoMeG - - - ERC-2016-STG - - - 713998 - - - - - NATURAL HISTORY MUSEUM - - - EUR 195 454,80 - - - Adaptations to temperature regimes in sponges: Genomic insights into the developmental and physiological evolutionary changes of early-branching metazoans - - - EUR 195 454,80 - - - United Kingdom - - - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - Species which inhabit the Antarctic have evolved to exist in some of the most challenging conditions found anywhere on the planet. Marine creatures must cope with sea temperatures generally ranging between 0 to -1.8 degrees - Celsius and a food supply which fluctuates widely from summer to winter, rendering their survival difficult. Nevertheless, species have found the means to thrive in such conditions. Their adaptation to cold environments will have included a host of - genetic changes, and to date we still know little about the nature of these molecular adaptations, the way these act in vivo, and the exact benefits such changes confer. - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ADAPTOMICS - - - H2020-MSCA-IF-2016 - - - 750937 - - - - - WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER - WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER - - - EUR 1 493 750 - - - Systems Chemistry Approach towards Semiconductive Supramolecular Copolymers with Homo- and Heterometallophilic Interactions - - - EUR 1 493 750 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Infinite one-dimensional structures with a metallic main chain of short metal-metal contacts have attracted considerable attention in the field of materials science for many decades due to their excellent optical properties - and remarkable dichroism and electrical (semi)conductivity. These materials suffer, however, from decomposition prior to melting and low solubility and processability. The strategy of introducing alkyl side chains of different nature in the past two - decades proved to be particularly successful towards better soluble materials or gels with implications in optoelectronics. However, this comes at the price of reduced bulk conductivities leading in some cases to electrical insulators due to the - perturbation of the metal-metal contacts. - - 2022-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Germany - - - SUPRACOP - - - ERC-2016-STG - - - 715923 - - - - - INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE - - - EUR 173 076 - - - Digestive and nutritional indicators of feed efficiency in cattle fed forage-based diets - - - EUR 173 076 - - - France - - - Research Organisations - - As the human population approaches 9.5 billion in 2050, and societies as a whole become more affluent, the demand for meat and milk is projected to nearly double. The current challenge facing humanity is to achieve food - security in a sustainable manner. As such, sustainable livestock production must be targeted towards the efficient use of feeds not suitable for human consumption. As a result of their symbiotic rumen microbial population, ruminants are strong - targets for manipulation as they can convert fibrous forages and low quality nitrogen sources into high protein meat and milk. Evaluation of the feed efficiency of ruminants fed non-competitive feed resources is an important avenue to increase the - profitability and sustainability of European ruminant farming systems. Feed efficiency is a complex trait that is lengthy and costly to phenotype. Additionally, in order to provide a comprehensive evaluation of the “sustainable” phenotype, newer - sustainability parameters, such as methane emissions and nitrogen losses need to be incorporated. Metabolism and digestion have been described as the two most important physiological drivers of variation of feed efficiency in ruminants. Thus, the - objective of this proposal is to explore potential biomarkers and microbial indicators of feed efficiency in growing cattle fed forage-based diets to improve our understanding of the physiological basis of efficient animals. Using feed conversion - efficiency and residual feed intake as benchmark indexes of efficiency, we will test and improve the use of modern isotopic N fractionation and rumen microbial phylotyping techniques as practical tools to evaluate feed efficiency in ruminants and to - better understand and correlate the rumen microbial community signature to an efficiency phenotype. These biomarkers could be used as an early evaluation tool in young animals and in commercial settings for selection and assessment of nutritional - management problems. - - 2017-08-31, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - MarkEfficiency - - - H2020-MSCA-IF-2014 - - - 658126 - - - - - DIETARY MOLECULAR DIAGNOSTICS SL - - - EUR 158 121,60 - - - Personalized Metabolomics for Fitness and Training - - - EUR 158 121,60 - - - Spain - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Increasing physical activity (PA) is currently widespread among the population. Thus, in addition to the professional, the amateur and the physically inactive persons being engaged for many different reasons, PA is considered - a major driver for optimal health achievement throughout life. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-SE - Society and Enterprise panel - - - Spain - - - PERMETFIT - - - H2020-MSCA-IF-2016 - - - 748829 - - - - - XILINX IRELAND UNLIMITED COMPANY - - - EUR 93 933 - - - Tensor Processing on FPGAs for Artificial Neural Networks - - - EUR 93 933 - - - Ireland - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Artificial neural networks have been shown to offer a powerful computing approach to encounter many classification problems as in synthetic vision (e.g. autonomous driving) and artificial intelligence (e.g. AlphaGo). While - their implementations are often based on power-hungy CPU- and GPU-installations, first researchers have delivered initial application-specific solutions that demonstrate FPGAs to be a feasible and efficient alternative. This proposal aims at - providing a generic reference implementation of ANNs on FPGAs that is tunable towards various application needs by parametrization. Since individual FPGA designs establish enormous costs of entry due to a higher engineering effort on a lower - abstration level, an IP core that is available out of the box is a great R&D incentive that enables more researchers and engineers to embrace the emerging efficient heterogeneous computing more quickly and produce innovations and more compact and - more efficient products on this basis. Besides this technological advance, this proposal enables a researcher with an enormous experience in mapping computations into FPGA hardware to make a valuable industrial experience in an international context - with the major company in this domain. His expertise is ideally complemented with the application experience available at Xilinx who will benefit from opening a new growing market for manufactured FPGA devices. The development of the researcher's - skill set is explictly addressed by complementing his academic background with industrial experience and scheduled cooperate trainings. As part of the dissemination activities, his network into the FPGA community is strengthened and approaches - towards the ANN community are made. - - 2018-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-SE - Society and Enterprise panel - - - Ireland - - - TPANN - - - H2020-MSCA-IF-2016 - - - 751339 - - - - - BOURNEMOUTH UNIVERSITY - INSTITUTUL DE MECANICA SOLIDELOR - ROBOTNIK AUTOMATION SLL - STIMPEX SA - CEDRAT TECHNOLOGIES SA - - - EUR 513 000 - - - SMart rObOTs for fire-figHting - - - EUR 909 000 - - - United Kingdom - Romania - Spain - Romania - France - - - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Over the years, changes in modern infrastructure have introduced new challenges to firefighting practices. Training and research programs have been developed to manage these challenges but there are still significant losses - from fires each year. In 2013 alone, the fire departments in the USA responded to over 1.2 million fires which resulted in about 3,420 civilian fatalities, 15,925 injuries and property losses of about $12.4 billion dollars. In the UK, 192,600 fires - responses, approximately 350 civilian fatalities, 10,300 injuries. The firefighting and rescue functions of the existing equipment and apparatus and their dexterity are limited, particularly in the harsh firefighting environments. The SMOOTH project - aims to propose a novel robot-assisted decision making system in smart firefighting to perform searching and rescuing practice in the fire ground, and to facilitate the decision makings with higher efficiency. - - - 2021-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2016 - Research and Innovation Staff Exchange - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - United Kingdom - - - SMOOTH - - - H2020-MSCA-RISE-2016 - - - 734875 - - - - - WAGENINGEN UNIVERSITY - - - EUR 177 598,80 - - - Following Protein Diffusion in Photosynthetic Membranes with Super Resolution - - - EUR 177 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - The regulated diffusion of light-harvesting complexes in photosynthetic membranes is essential for photosynthesis, for instance for the redistribution of light-harvesting complexes between Photosystems I and II. To date, - however, little is understood about the mobility of these proteins through the highly crowded membrane environment. In contrast to the huge amount of structural research that has been performed on biomolecules in the past, research on the dynamics is - lagging far behind. The major limitation is the fact that the nanometer size regime of biomolecules is not accessible by classical optical techniques owing to the diffraction limit of light. To overcome this problem, we propose to use plasmonic - nanoantennas, which are able to confine light at the nanoscale. In combination with Fluorescence Correlation Spectroscopy (FCS) this will allow measuring protein mobility in photosynthetic membranes with high, tens of nanometers, resolution. - Directional and functional protein movement will be induced by illumination of the chloroplasts using specific light conditions; simultaneously following the protein movement will give new insights in how plants optimize their light harvesting - capacity under fluctuating light conditions. The new nanoantenna-FCS based method, which we will develop to measure the diffusion of membrane proteins with nanometer resolution, has the potential to become widely used for nanobioimaging and - ultrasensitive biosensing. - - 2017-09-13, Grant Agreement terminated - - - 2015-09-14 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - MeaSuRe - - - H2020-MSCA-IF-2014 - - - 655542 - - - - - INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE - UNIVERSITAET FUER BODENKULTUR WIEN - MADERA PLUS CALIDAD FORESTAL SL - - - EUR 675 000 - - - Wood phenotyping tools: properties, functions and quality - - - EUR 675 000 - - - France - Austria - Spain - - - Research Organisations - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - The objective of TOPWOOD is to build a four-year scientific exchange program about the test and development of medium and high-throughput phenotyping measurement and analysis tools for selected basic wood properties in the - laboratory and in the field (TOols for Phenotyping WOOD-TOPWOOD). The participants wish to exchange knowledge and experience for sharing and expanding skills, improving existing tools and developing new original measuring devices for wood properties - involved in studies of wood quality and of wood biological functions. The phenotyping tools and methods of analysis developed and improved in TOPWOOD are intended to be used by the participants to investigate the genetic and environmental determinism - of key wood properties involved in forest tree adaptation, as well as in wood production and wood quality for the forest and wood industries. The participants of TOPWOOD are three academic institutions and one private company from three European - Union countries, Austria, France and Spain, and one third country, Argentina. - - - 2019-03-31, ongoing project | - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2014 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - France - - - TOPWOOD - - - H2020-MSCA-RISE-2014 - - - 645654 - - - - - UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA - - - EUR 170 121,60 - - - Multifunctional luminescent and magnetic nanoparticles for advanced biomedical applications - - - EUR 170 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - The key goals of the “LUMIMAGNET-NANO” project are: (a) the training of a talented young researcher, Dr. Rosa Martín-Rodríguez, in the fast growing field of science, technology and industrial applications of nanomedicine, - where the host and partner institutions have a critical knowledge and expertise; and, (b) the design, development and optimisation of cost-efficient magnetic nanoparticles with multifunctional recovering for biomedical applications. - - 2017-05-17, Grant Agreement terminated - - - 2015-05-18 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - LUMIMAGNET-NANO - - - H2020-MSCA-IF-2014 - - - 658806 - - - - - UNIVERSITA DEGLI STUDI DI PAVIA - UNIVERSITA DEGLI STUDI DI PAVIA - AVANTEA srl - FUNDACION CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III - - - EUR 2 314 029 - - - Molecular strategies to treat inherited arrhythmias - - - EUR 2 314 029 - - - Italy - Italy - Italy - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - - Sudden cardiac death (SCD) is a leading cause of death in western countries: coronary artery disease is the major cause of SCD in older subjects while inherited arrhythmogenic diseases are the leading cause of SCD in younger - individuals. After 25 years dedicated to research of the molecular bases of heritable arrhythmias, the PI of this proposal now intends to pioneer gene therapy for prevention of SCD: a virtually unexplored field. The development of molecular therapies - for rhythm disturbances is a high risk effort however, if successful, it will be highly rewarding. The PI has envisioned an ambitious and comprehensive project to target two severe inherited arrhythmogenic diseases: dominant catecholaminergic - polymorphic ventricular tachycardia (CPVT) and Long QT syndrome type 8 (LQT8). The availability of a clinically relevant model is critical to ensure clinical translation of results: the team will exploit an existing CPVT model and will engineer a - knock-in pig to model LQT8. The PI and her team will investigate innovative strategies of gene-delivery, gene-silencing and gene-editing to the heart comparing efficacy of different constructs and promoters. The team will also carefully engineer - novel gene-therapy approaches to avoid the development of regional inhomogeneity in protein expression that may facilitate proarrhythmic events. Such a comprehensive approach will provide a most valuable core of knowledge on the comparative efficacy - of a broad range of molecular strategies on the electrical milieu of the heart. It is expected that these results will not only benefit CPVT and LQT8 but rather they will foster development of gene therapy for other inherited and acquired - arrhythmias. - - 2020-10-31, ongoing project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2014 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - Italy - - - EU-rhythmy - - - ERC-2014-ADG - - - 669387 - - - - - UNIVERSITA' DEGLI STUDI DI SIENA - UNIVERSITA DI PISA - UNIVERSITA DEGLI STUDI DI FIRENZE - UNIVERSITA PER STRANIERI DI SIENA - SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO SANT'ANNA - SCUOLA NORMALE SUPERIORE - SCUOLA IMT (ISTITUZIONI, MERCATI, TECNOLOGIE) ALTI STUDI DI LUCCA - - - EUR 160 000 - - - Brilliant Researchers Impact on Growth Health and Trust in research. - - - EUR 160 000 - - - Italy - Italy - Italy - Italy - Italy - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The BRIGHT project aims at enhancing the visibility and perception of researchers among the general population in the Tuscany Region, simultaneously with all the European Researchers’ Night (ERN) initiatives. - - 2018-01-31, closed project - - - 2016-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.5."> - - - MSCA-NIGHT-2016 - European Researchers' Night - - - CSA - Coordination and support action - - - Italy - - - BRIGHT - - - H2020-MSCA-NIGHT-2016 - - - 722944 - - - - - OXFORD BROOKES UNIVERSITY - THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - - - EUR 269 857,80 - - - (Un)Just NeighbourhoodsSocio-Spatial Justice in Urban Neighbourhoods - - - EUR 269 857,80 - - - United Kingdom - United States - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Rapid urbanisation, growing process of globalisation, and the neoliberal hegemony have culminated in the omnipresence of socio-spatial inequalities at the neighbourhood scale regarding racial segregation, deprivation, - stigmatisation, and degradation. European and North American cities, among others, have initiated neighbourhood-oriented urban redevelopment schemes to mitigate the burden of urban injustice. However, there is no integrated framework to evaluate - their achievements, the contribution of urban neighbourhoods to just cities has not been systematically investigated. To address this lacuna, the project conceptualises the idea of (un)just neighbourhoods from socio-spatial justice perspective and - develops an evaluation framework for measuring key qualities of socio-spatial justice at the neighbourhood scale. - - 2021-01-09, ongoing project - - - 2018-01-10 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - Justhood - - - H2020-MSCA-IF-2016 - - - 748452 - - - - - INSTITUTO DE ASTROFISICA DE CANARIAS - - - EUR 158 121,60 - - - Polarimetry of Anomalous Microwave Emission: Implication for B-mode Polarization Detection and Galactic Science - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - Anomalous Microwave Emission (AME) is potentially polarized in the frequency range [1-100] GHz. The polarization properties of this astrophysical signal have to be characterized and understood completely for one willing to - remove Galactic foregrounds in order to detect B-mode polarization for cosmology. The characterization of AME polarization properties is also fundamental in term of Galactic Astrophysics to understand the mechanisms producing the AME. The PolAME - project aims to use the QUIJOTE-CMB experiment and its two instruments (the MFI and the TGI) for measuring the degree of polarization of the AME in the domain range [10-30] GHz on a sample of selected sources. This new data, in addition to new C-BASS - data and the WMAP and PLANCK maps and ancillary data will be compared to theory and state-of-the-art modelling results. The Galactic science community will greatly benefit the new advances that will be provided by the PolAME project. The main outcome - of this project will lead to a stronger characterization of the Galactic Polarized Foregrounds which is fundamental for cosmology. Knew knowledge will be produced about our understanding of the nature of the AME and dust grain evolution processes in - our Galaxy. - - 2017-12-31, closed project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - PolAME - - - H2020-MSCA-IF-2014 - - - 658499 - - - - - INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE - - - EUR 185 076 - - - Single cell biophysics of bacterial cell shape - - - EUR 185 076 - - - France - - - Research Organisations - - In bacteria, the rigid external cell wall (CW) and the intracellular actin-like (MreB) cytoskeleton are major determinants of cell shape. Synthesis and chemical composition of the CW, a three dimensional polymer network that - is one of the most prominent targets for antibiotics, are well understood. However, despite decades of study, little is known about the complex CW ultrastructure and the molecular mechanisms that control cell shape in time and space. MreB homologues - assemble into dynamic membrane-associated structures thought to control shape by serving as organizers for the movement and assembly of macromolecular machineries responsible for CW biogenesis. However, the mechanistic details used by the MreB - cytoskeleton to fulfill this role remain to be elucidated. - - - 2017-03-31, closed project | - - - 2015-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - France - - - BACTOSHAPE - - - H2020-MSCA-IF-2014 - - - 660935 - - - - - INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE - - - EUR 173 076 - - - Unveiling Stomata 24/7: Using Stable Isotopes and COS to quantify diurnal and nocturnal carbon and water vegetation-atmosphere Fluxes under future climate scenarios - - - EUR 173 076 - - - France - - - Research Organisations - - Rising atmospheric CO2 concentration, increasing temperature and altered precipitation patterns dramatically impact the terrestrial biosphere with important consequences for all biogeochemical cycles. Predictions of carbon (C) - and water exchange between vegetation and the atmosphere require detailed mechanistic understanding of how plants control water loss and C gain through their stomatal pores. Currently, global circulation models incorporate formulations of stomatal - conductance (gs) based on stomatal optimisation theory. However, these models ignore gs regulation: (1) during night time, despite clear evidence for significant nocturnal transpiration, (2) in non-vascular plants and (3) during leaf development and - senescence. To reduce the uncertainty associated with current C and water fluxes in models, we need to incorporate robust predictions of gs in response to novel environmental conditions (higher temperature, decreased water availability and elevated - CO2). To fill these gaps, USIFlux, will develop a novel tracing technique to measure gs during the dark, when fluxes are an order of magnitude smaller than during the day. To do so, we will combine measurements of COS (carbonyl sulphide) uptake with - CO18O fluxes and changes in the oxygen isotope composition (δ18O) of water in leaves. We will relate the response of gs at night to changes in gs during the day and in response to drought and elevated CO2. These measurements will be coupled to an - experiment to investigate stomatal regulation during leaf ontogeny and in different life forms. Here, we will challenge the stomatal optimisation theory in life forms lacking active stomatal control (mosses and brackens) and during leaf development, - when leaf construction costs constrain the optimisation of C gain. Empirical formulations arising from these experiments will be incorporated into large-scale soil-vegetation-atmosphere transfer models to explore their impact at larger scales. - - 2018-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - USIFlux - - - H2020-MSCA-IF-2014 - - - 653223 - - - - - UNIVERSITA CA' FOSCARI VENEZIA - - - EUR 180 277,20 - - - Uncovering information in fluctuating CLimate systems: An oppoRtunity for solving climate modeling nodes and assIst local communiTY adaptation measures - - - EUR 180 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - A consistent picture of climate variability is pivotal for understanding its evolution. CLARITY intends to apply advanced statistical methods developed in the field of statistical physics to analyze, interpret and incorporate - into modelling strategies observed, reconstructed, as well as simulated climate data. To achieve this ambitious goal valuable information from fluctuations in climate records will be uncovered. The obtained results will constitute the input for a - Bayesian modelling strategy, aimed then at improving modelling reliability. Once operational, this approach will be applied to a series of climatically relevant issues. On a local scale (city of Venice, Italy), particularly, climate records related - to temperature, humidity and the ultraviolet radiation exposure of city’s school populations will be collected and used to obtain projections that can be of assistance to community needs. - - - 2018-05-08, ongoing project - - - 2016-05-09 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - CLARITY - - - H2020-MSCA-IF-2015 - - - 701785 - - - - - INSTITUT CURIE - INSTITUT CURIE - - - EUR 2 499 697 - - - Chromatin Adaptations through Interactions of Chaperones in Time - - - EUR 2 499 697 - - - France - France - - - Research Organisations - Research Organisations - - A central question in chromatin biology is how to organize the genome and mark specific regions with histone variants. Understanding how to establish and maintain, but also change chromatin states is a fundamental challenge. - Histone chaperones, escort factors that regulate the supply, loading, and degradation of histone variants, are key in their placement at specific chromatin landmarks and bridge organization from nucleosomes to higher order structures. A series of - studies have underlined chaperone-variant partner selectivity in multicellular organisms, yet recently, dosage imbalances in natural and pathological contexts highlight plasticity in these interactions. Considering known changes in histone dosage - during development, one should evaluate chaperone function not as fixed modules, but as a dynamic circuitry that adapts to cellular needs during the cell cycle, replication and repair, differentiation, development and pathology. - - 2021-06-30, ongoing project - - - 2016-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-ADG-2015 - ERC Advanced Grant - - - ERC-ADG - Advanced Grant - - - France - - - ChromADICT - - - ERC-2015-AdG - - - 694694 - - - - - DE MONTFORT UNIVERSITY - - - EUR 195 454,80 - - - Design, fabrication and optimization of a novel integrated UV-microwave assisted catalytic reactor for the continuous flow treatment of wastewater - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - UVMICROCAT uses an innovative catalytic mesh assisted by a combination of UV and microwave technology for fast and effective treatment of large volumes of wastewater for water re-use. - - 2017-08-31, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - UVMWREACT - - - H2020-MSCA-IF-2014 - - - 661048 - - - - - INSTITUT CURIE - - - EUR 173 076 - - - Fibroblasts in the Biology of Rectal Cancer Progression - - - EUR 173 076 - - - France - - - Research Organisations - - Although the therapeutic strategies adopted in the last years for the clinical management of patients with rectal cancer have improved patient’s quality of life, tumor relapse still constitutes to be a factor that determines - patient survival. These patients, usually treated with chemo-radiotherapy (CRT), often develop a CRT-induced fibrosis, which is characterized by an overgrowth of fibroblasts at tumor-treated areas. The importance of tumor stroma for the development, - progression and invasion of cancer is increasingly gaining weight, however, the biological basis of fibrosis, as well as the consequences that it has in terms of therapy resistance and tumor relapse remain unknown. The major objective of this - proposal is to understand the effect of CRT on fibroblasts and its consequences on tumor relapse and formation of distant metastasis. To reach this, we propose a multidisciplinary approach that combines the analysis of unique patient-derived - biological samples using innovative and advanced techniques in molecular and cell biology. More specifically, using a proteomic approach and primary cultures of fibroblasts derived from rectal tumors taken before and after CRT from the same patient, - we will determine the effect of CRT on the molecular alterations in fibroblasts. Then, using 3D in vitro models we will determine if CRT-derived fibroblasts play a role in therapy resistance, proliferation and invasion of cancer cells, while - ortothopic mouse models will be used to test if CRT-derived fibroblasts can trigger rectal cancer progression and metastasis. Finally, using previously collected clinical data of rectal cancer patients we will analyze if tumor relapse is related to - the appearance of fibrosis and, if it has a positive or negative prognosis value - - 2018-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - FiBRO - - - H2020-MSCA-IF-2014 - - - 659776 - - - - - FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - UNIVERSITEIT GENT - UNIVERSITEIT UTRECHT - TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK - THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - CORNELL UNIVERSITY - - - EUR 859 500 - - - Colloidal Nanomaterials for Smart Applications - - - EUR 859 500 - - - Italy - Germany - Belgium - Netherlands - United States - United States - United States - - - Research Organisations - Chiara Andreoli - Tel.: +3901071781854 - Fax: +39 010 7170817 - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - "The COMPASS project unites key players in Europe and the US with the aim to advance the field of colloidal nanocrystal (NC) synthesis and assembly and their exploitation in photonics, sensing, energy conversion and medicine. - COMPASS aims to (i) develop colloidal NCs with desired properties by controlling their size, shape and composition, and to demonstrate routes allowing for large production volumes with nearly identical size and shape; (ii) develop approaches for NC - self-assembly in ordered superlattices constituting NC solids with novel properties; (iii) understand the optoelectronic properties of novel NC-based materials by advanced optical and scanning probe spectroscopy methods, and explore pathways for - their implementation in light emission, sensing, energy conversion and medicine; (iv) establish a consolidated network between leading EU and US institutes to provide a stimulating international environment for talented young researchers; (v) advance - the level of R&D in Europe and the US and foster technology transfer and dissemination; (vii) raise the awareness of the general public on the prospects of NC materials in future technologies. Young scientists will be formed by ""training by - research"" in long term stays at host labs and by lecture series held in the network that cover specific research topics, technology transfer and management/communication skills, leading to an interdisciplinary and international formation. The - exchange will consolidate existing initial links between some of the lead scientists in COMPASS and establish a long lasting network that will have strong impact on science and education with significant repercussions in industry. The work plan is - divided in 5 strongly linked workpackages that deal with Management, NC Fabrication, Self Assembly and Surface Functionalization, Photonics and Optoelectronics, and Energy Conversion. COMPASS will be guided by an executive board that consists of the - coordinator and the lead PIs of the partners." - - 2020-02-29, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Italy - - - COMPASS - - - H2020-MSCA-RISE-2015 - - - 691185 - - - - - ANGLIA RUSKIN UNIVERSITY HIGHER EDUCATION CORPORATION - - - EUR 183 454,80 - - - Pluralistic Economics for Development in Green Economic Enhancement - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The question of which economic framework (or sets of frameworks) is (are) appropriate for providing policy prescriptions conducive to ecological sustainable has gained renewed interest within the community of ecological - economists and political economists. To help answer this question I propose to investigate the suitability of four economic frameworks — neoclassical environmental economics, non-Walrasian neoclassical environmental economics, institutional - ecological economics, and ecological Marxian political economy, for providing effective and coherent policy prescriptions for renewable and sustainable energy resources, specifically for electricity generation. - - 2017-12-31, closed project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - PEDIGREE - - - H2020-MSCA-IF-2014 - - - 655274 - - - - - INSTITUT CURIE - - - EUR 185 076 - - - Evolutionary conserved T cells specific for a microbial metabolite: deciphering their development in the thymus and mapping their interactions with the gut microbiota in vivo. - - - EUR 185 076 - - - France - - - Research Organisations - - Mucosal Associated Invariant T cells (MAITs) represent an evolutionary conserved subset that express a semi-invariant TCR recognizing a new class of microbial metabolite antigens presented by the MHC class Ib molecule, MR1. In - addition to their wide anti-microbial specificity, the high inter-species conservation of both MR1 and invariant TCR infers an important biological role for MAITs. MAITs are abundant in human blood (1-8 % of T cells), mucosa and liver (20-50%). After - development in the thymus, MAITs reach the periphery where they acquire a memory phenotype and expand in a process that requires a commensal flora, indicating that MAITs play a role in host-commensals interactions. Admittedly MAITs blood frequency is - modified in several pathologies in which dysbiosis of the gut microbiota has been implicated such as IBD, MS, type 2 diabetes and obesity. - - 2018-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - France - - - MAIT - - - H2020-MSCA-IF-2015 - - - 706353 - - - - - TECHNISCHE UNIVERSITAET ILMENAU - AVL LIST GMBH - COVENTRY UNIVERSITY - FLANDERS MAKE VZW - INFINEON TECHNOLOGIES AG - KATHOLIEKE UNIVERSITEIT LEUVEN - SKODA AUTO A.S. - UNIVERSITA DEGLI STUDI DI PAVIA - UNIVERSITE DE TECHNOLOGIE DE COMPIEGNE - Kompetenzzentrum - Das Virtuelle Fahrzeug, Forschungsgesellschaft mbH - VOLVO PERSONVAGNAR AB - - - EUR 3 833 413,20 - - - Interdisciplinary Training Network in Multi-Actuated Ground Vehicles - - - EUR 3 833 413,20 - - - Germany - Austria - United Kingdom - Belgium - Germany - Belgium - Czech Republic - Italy - France - Austria - Sweden - - - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - "The main target of the ITEAM project is to establish and sustainably maintain the European training network with high grade of interdisciplinarity, which will train strong specialists skilled in research and development of - novel technologies in the field of multi-actuated ground vehicles (MAGV). The global goals are: (i) Advance of European postgraduate education in the area of environment- and user-friendly vehicle technologies that highly demanded by the European - industry and society; (ii) Reinforcement of cooperation between academia and industry to improve career perspectives of talented graduates in both public and private sectors; (iii) Creation of strong European research and innovation group making - determinant contributions to next generations of multi-actuated ground vehicles. To achieve the project objectives, the consortium unites 11 beneficiaries and 5 partner organizations from 9 European countries including 7 universities, 2 research - centres, and 7 non-academic organizations. Distinctive feature of the ITEAM network is the concept of interaction of three research clusters: "MAGV integration", "Green MAGV", "MAGV Driving Environment". Within these clusters, the training concept - will be based on intersectoral cooperation and will cover domains of (i) basic research, (ii) applied research, and (iii) experimentations. The ITEAM project will provide the first-of-its kind European training network in Ground Vehicles at doctorate - level to fill up the niche in private sector and industry with researcher-practitioners. The proposed network will be developed as innovative, multidisciplinary, engineering product-oriented and project-based program to train the scientists by - integrating cutting-edge research methods of ground vehicles, electric/mechatronic systems, environmental engineering and applied intelligent control. The ITEAM network measures will guarantee excellent career prospects for participating researchers - both in industrial and academic sectors." - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - Germany - - - ITEAM - - - H2020-MSCA-ITN-2015 - - - 675999 - - - - - UNIVERSIDAD DE SANTIAGO DE COMPOSTELA - - - EUR 239 191,20 - - - Designing Novel Phonon Valve Device through Ferroic Domain Wall Engineering - - - EUR 239 191,20 - - - Spain - - - Higher or Secondary Education Establishments - - Much of the major technological breakthroughs occurring in the last few decades rely on our enhanced capability to control and manipulate two particles: electrons (both charge and spin) and photons. Achieving a similar degree - of control over phonons would be extraordinarily valuable as we will be able to channel thermal energy at will –thus propelling new possibilities for energy management– as well as the development of a completely novel technology for logic, data - storage devices and computing mechanisms based on phonons. - - 2019-09-25, ongoing project - - - 2016-09-26 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Spain - - - PHONON-VALVE - - - H2020-MSCA-IF-2015 - - - 708129 - - - - - INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE - - - EUR 185 076 - - - Methodologies Yielding CLimate IMpact Assessments Through Economics - - - EUR 185 076 - - - France - - - Research Organisations - - Humans rely for their food on agricultural products. Agricultural production relies on soil, climate, agricultural inputs, and farmers. The importance of climate and soil inputs has been recently reconsidered in agricultural - production. However, the quantification of the impact of climate change on agricultural production has been conducted with regression methods that impose undesired assumptions on the obtained results. If it is true that climate is changing, an - estimation of climate change impacts on agriculture free of undesired assumptions is the key to understanding a strategy towards a sustainable future. Going beyond the methodological approaches proposed in previous studies, in this action I bridge - the gap between production economics and the agronomic and climate economics literature. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - MYCLIMATE - - - H2020-MSCA-IF-2015 - - - 705360 - - - - - WAGENINGEN UNIVERSITY - WAGENINGEN UNIVERSITY - UNIVERSITEIT UTRECHT - RIJKSUNIVERSITEIT GRONINGEN - UNIVERSITY OF LEEDS - INSTITUTO NACIONAL DE PESQUISAS ESPACIAIS - - - EUR 2 269 688,76 - - - New constraints on the Amazonian carbon balance from airborne observations of the stable isotopes of CO2 - - - EUR 2 269 688,76 - - - Netherlands - Netherlands - Netherlands - Netherlands - United Kingdom - Brazil - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - Severe droughts in Amazonia in 2005 and 2010 caused widespread loss of carbon from the terrestrial biosphere. This loss, almost twice the annual fossil fuel CO2 emissions in the EU, suggests a large sensitivity of the - Amazonian carbon balance to a predicted more intense drought regime in the next decades. This is a dangerous inference though, as there is no scientific consensus on the most basic metrics of Amazonian carbon exchange: the gross primary production - (GPP) and its response to moisture deficits in the soil and atmosphere. Measuring them on scales that span the whole Amazon forest was thus far impossible, but in this project I aim to deliver the first observation-based estimate of pan-Amazonian GPP - and its drought induced variations. - - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - ASICA - - - ERC-2014-CoG - - - 649087 - - - - - UNIVERSITA DEGLI STUDI DI PAVIA - UNIVERSITA DEGLI STUDI DI PAVIA - ISTITUTO NAZIONALE DI FISICA NUCLEARE - - - EUR 1 509 000 - - - 3-Dimensional Maps of the Spinning Nucleon - - - EUR 1 509 000 - - - Italy - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - - How does the inside of the proton look like? What generates its spin? 3DSPIN will deliver essential information to answer these questions at the frontier of subnuclear physics. - - 2020-06-30, ongoing project - - - 2015-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Italy - - - 3DSPIN - - - ERC-2014-CoG - - - 647981 - - - - - INSTITUT CURIE - INSTITUT CURIE - - - EUR 1 999 900 - - - Unravelling the Genomic Targets of Drugs Using High-Throughput Sequencing - - - EUR 1 999 900 - - - France - France - - - Research Organisations - Research Organisations - - This proposal is centred on the development of small molecule probes derived from DNA damaging agents to identify their genomic targets using a novel unbiased approach. Although, several genotoxic drugs have been used for - decades to treat cancers, the exact mechanisms by which they operate are not fully understood. It is established that these compounds interfere with the processes of transcription and replication, thereby promoting genomic instability and cell death. - However, there is as yet no genome-wide map of the exact location of sites that are putative targets for these drugs in vivo. This information is critical to understand and rationalize cellular responses to genotoxic agents. Here, we propose to - develop an innovative discovery- based methodology that will combine click chemistry in situ, affinity pull-down techniques and high throughput DNA sequencing (Drug-Seq), to identify the genomic interactome of DNA damaging drugs in order to elucidate - their cellular activity at the molecular level. Two independent lines of enquiry will be followed. Firstly, we will establish the genomic interacting landscape of landmark drugs including etoposide, camptothecin and cisplatin using Drug-Seq. - Secondly, we will perform regular chromatin immuno- precipitation sequencing (ChIP-Seq) of selected proteins linked to the cellular response of interest to validate Drug-Seq and further identify druggable genomic sites. An important aim of this - proposal is to establish a universal methodology to decipher small molecule/genome interactions in vivo that trigger a particular response in disease-relevant models. We also seek to interrogate the role of chromatin in regulating drug/genome - interactions and to define whether it is possible to act on the epigenome to modulate the activity and specificity of these drugs. Collectively, we anticipate our study will lay down the foundation for personalized medicine with the implementation of - rational rather than empirical clinical protocols. - - 2020-08-31, ongoing project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2014 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - France - - - Drug-Seq - - - ERC-2014-CoG - - - 647973 - - - - - INSTITUT CURIE - - - EUR 185 076 - - - Functions of Integrins in Mammary Stem Cell Activity and Tumorigenesis - - - EUR 185 076 - - - France - - - Research Organisations - - Understanding the functional interactions between mammary epithelium and its microenvironment, with a particular focus on the stem cell niche, represents a challenge for developmental and cancer biologists. Mammary epithelium - is a bilayer, with a layer of luminal cells, producing milk, and a layer of basal myoepithelial cells. Both layers contain clonogenic stem/progenitor cells, which ensure the drastic epithelial expansion in puberty and pregnancy. Whilst basal stem - cells are thought to be bipotent, luminal progenitors appear to be lineage-restricted in normal gland. Recent studies indicated that basal-like breast tumors, notably those with BRCA1 mutations, might originate from luminal progenitors. Our project - aims to elucidate the role of integrin receptors for Laminin, major component of the mammary basement membrane, in the regulation of the luminal progenitor function during normal mammary development and tumorigenesis. To this end, α3 and α6 integrin - chains were deleted from mammary luminal cells in vivo using CreLoxP system. Cre expression was driven to luminal progenitors by the Blg promoter, activated in this cell population in adult virgin mice and further on, during lobulo-alveolar - development in pregnancy. The stem cell activity and the maintenance of the stem cell populations in mutant mammary glands will be analyzed at different developmental stages. Morphogenesis, proliferation, survival, differentiation as well as the - regenerative and clonogenic potential of the mutant epithelium will be examined. We will study the cytoskeleton organization and the capacity of mutant cells for baso-apical polarization. To analyze the responses of integrin-depleted cells to - hormones and growth factors at the molecular level, organotypic ex vivo cultures will be employed. The impact of Laminin-binding integrins on abnormal luminal progenitor amplification during tumor initiation will be tested in a mouse model of - basal-like breast cancer induced by p53 and BRCA1 loss. - - 2018-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - France - - - INTEGRISTEM - - - H2020-MSCA-IF-2015 - - - 704960 - - - - - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - - - EUR 183 454,80 - - - Unravelling the mechanisms regulating cellular fitness during embryonic development - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Understanding the mechanisms that eliminate unfit cells during development is key not only for proper organ formation but also to prevent tissue degeneration in the adult. Cell competition is a fitness quality control - mechanism that occurs between cells of differing fitness levels and results in the selective elimination of those cells that, although viable, are deemed to be less fit than their neighbours. Cell competition is conserved from Drosophila to mammals - and although some important regulators of this process have been identified, the mechanisms by which less-fit cells are eliminated are not well understood. Preliminary work in the Rodriguez laboratory has identified the mTOR pathway, a key metabolic - sensor, as a possible regulator of cell competition in pluripotent stem cells. A small molecule screen for modulators of cell competition identified that inhibiting mTOR enhances defective pluripotent stem cell elimination during competition, and - further studies revealed that mTOR activity is decreased in loser cells when confronted with winner cells. I will study the possibility that mTOR acts as a sensor of the competitive nature of pluripotent stem cells. The specific aims of this project - are to find what pathways lead to differential mTOR activation during competition and unravel the mechanisms by which loss of mTOR leads to the elimination of defective stem cells. To answer these questions I will use mouse embryonic stem cells, as - well as validate the in vivo relevance of my findings by studying the mouse embryo. - - 2018-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - CFED - - - H2020-MSCA-IF-2015 - - - 709010 - - - - - Consortium of European Research Libraries - - - EUR 183 454,80 - - - PATRIMONiT. From Cheap Print to Rare Ephemera: 16th-Century Italian 'Popular' Books at the British Library - - - EUR 183 454,80 - - - United Kingdom - - - Other - - Large quantities of 16th-Century Italian ‘popular’ books – the books read or ‘listened to’ by everyone during the Early Modern Period, printed with poor quality material and having usually a short life expectancy –, sometime - after the 16th century found their way to the UK to join the largest single collection of Italian 16th-century books in the world, that is the British Library (BL). This library preserves today a substantial number of early Italian editions which do - not survive in any Italian library and are still not adequately recorded. - - 2018-01-31, closed project - - - 2016-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - PATRIMONiT - - - H2020-MSCA-IF-2014 - - - 659625 - - - - - ANGLIA RUSKIN UNIVERSITY HIGHER EDUCATION CORPORATION - - - EUR 195 454,80 - - - ‘Reciprocal Encounters’ - Young Adults Leaving Care - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The objective of this proposal, ‘Reciprocal Encounters – Young Adults Leaving Care’, is not only to produce preventive, client-based social work guidelines regarding how to search for the best ways to support the well-being of - young adults with substitute care experiences and the process of their deinstitutionalisation or leaving substitute care, but it will also use a complementary participatory research methodology to explore the research questions, undertaking research - with young adults, not just on them, thus delivering user-driven results. - - 2018-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ReProCounters - - - H2020-MSCA-IF-2015 - - - 702989 - - - - - ANGLIA RUSKIN UNIVERSITY HIGHER EDUCATION CORPORATION - - - EUR 97 727,40 - - - Design of a serious game for cars to help increase driver skills and lower fuel consumption - - - EUR 97 727,40 - - - United Kingdom - - - Higher or Secondary Education Establishments - - New in-vehicle information systems and advanced driver assistance systems are currently being introduced in cars in order to help driving safely and energy efficiently. These systems help the driver to pay attention to - critical events (e.g. collision warnings and blind spot information systems) or deliver important information (e.g. speed limits and navigation instructions). However, safety and environmental impact are most of all dependent on the behaviour and - attitude of the driver. This proposal concerns the design of a serious game for cars that will help drivers to increase eco-driving skills, lower fuel consumption and encourage safe and environmentally friendly approaches to driving. Through his - research, Dr Arne Nykänen has developed successful methods and procedures for efficient product sound design, already implemented at Volvo Cars and Scania. Anglia Ruskin University has leading expertise on creative and user-centred design, serious - gaming, mobile applications and sound design for theatre and film. Combining this expertise enables the introduction of sound based serious gaming in cars. This provides a successful way to increase driving safety and decrease environmental impact of - cars, by not only informing and warning the driver, but also changing attitudes and behaviour. The major outcomes of the project will be a demonstrator of a serious game implemented in a car, a mobile app publicly available for download, - demonstrations at science centres in the UK and Sweden, 3 journal papers, participation in 4 conferences, and a new European expert network with partners from academia as well as car, game and audio engineering industry. - - 2016-08-31, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - Safe and Sound Drive - - - H2020-MSCA-IF-2014 - - - 657233 - - - - - INSTITUT CURIE - - - EUR 173 076 - - - Membrane-ezrin-actin interactions mediated by ezrin binding proteins in reconstituted systems - - - EUR 173 076 - - - France - - - Research Organisations - - Microvilli are tube-like membrane protrusions containing bundles of actin filaments located at the apical surface of epithelial cells. A key component of these microvilli is ezrin, a member of the Ezrin/Radixin/Moesin protein - family, which provides a regulated linkage between the plasma membrane and the actin cytoskeleton. The critical role of ezrin in microvillar morphogenesis has been demonstrated. However, how ezrin is recruited to the apical surface of the cells and - how ezrin contributes to the stability of microvillar morphogenesis remain elusive. Recently, a few ezrin binding partners, such as EBP50 and Eps8, have been identified and shown to function synergistically with ezrin in membrane and actin - remodelling in cells. The precise mechanisms and implications of their interactions in microvillar morphogenesis are not well understood. Lately, I-BAR domain protein IRSp53 was found to colocalize with ezrin in microvilli and interact with both - EBP50 and Eps8, as ezrin does. Given that I-BAR domain proteins participate in the formation of many cellular protrusions, such as filopodia, ezrin and I-BAR domain proteins may work synergistically in membrane remodelling. - - - 2017-12-31, closed project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - membrane-ezrin-actin - - - H2020-MSCA-IF-2014 - - - 656442 - - - - - INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE - - - EUR 185 076 - - - Mannan-related enzymes of wheat endosperm - - - EUR 185 076 - - - France - - - Research Organisations - - European society and economy relies on the productivity of staple food, such as wheat. Plant cell walls are a centrepiece of plant development and tuning their biosynthesis could improve the productivity and the quality of - wheat grain. Although the structure of cell wall polysaccharides is relatively well-documented, little is known about their biosynthesis. The project proposes for the first time 1) to explore the structure, organisation and function of mannan, a cell - wall polysaccharide that impacts on wheat grain development, and 2) to investigate the function of four putative genes involved in the mannan biosynthesis, using a combination of well established and new methodologies (enzymatic fingerprinting, FT-IR - microspectroscopy and MALDI-MS imaging). This research is of potential interest to various industrial sectors (e.g., plant breeding, milling and biofuel industries) active in Europe and represents a good opportunity to improve competitiveness of - European agriculture. Within the host institute (INRA, France), which is a World leader for agricultural sciences, the supervisor is internationally renowned for its contribution in the general understanding of plant cell walls. The host will offer - the opportunity to the fellow to develop a sound knowledge in biochemistry and molecular biology and will contribute to improve his managerial skills. In return, the fellow who has a strong expertise in microscopy and enzymatic activity assays will - implement these techniques in the host institution. The fellow will have the opportunity to disseminate his knowledge during various events towards audiences of scientists, students and the general public. The fellow will access to all the - facilities, logistics, and equipment necessary for the good implementation of his project. In summary, this innovative project will contribute to European excellence and will offer the training the fellow needs to pursue his career as an independent - principal investigator in plant science. - - 2018-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - MANAN - - - H2020-MSCA-IF-2015 - - - 708329 - - - - - UNIVERSITA DEGLI STUDI DI PAVIA - - - EUR 180 277,20 - - - Transitivity in Indo-Aryan: A diachronic syntactic data base of valence-changing categories - - - EUR 180 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - The proposed project aims at combining quantitative, corpus based research with qualitative research on language typology and language change. In particular, I plan to provide a thorough description of verbal valency and of - valency-changing categories in Old Indo-Aryan along with their development in Middle and New Indo-Aryan. - - - 2019-01-31, ongoing project - - - 2017-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - TRIA - - - H2020-MSCA-IF-2015 - - - 702895 - - - - - DE MONTFORT UNIVERSITY - UNIVERSITAT PASSAU - UNIVERSIDAD POLITECNICA DE MADRID - AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH - NOLDUS INFORMATION TECHNOLOGY BV - PHILIPS ELECTRONICS UK LIMITED - TECHNISCHE UNIVERSITAET WIEN - ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS - INGENIERIA Y SOLUCIONES INFORMATICAS DEL SUR, SOCIEDAD LIMITADA - UNIVERSITY OF ULSTER - - - EUR 3 874 054,68 - - - Advanced TeChnologies and PlatfoRm fOr Smarter ASsisted LivING - - - EUR 3 874 054,68 - - - United Kingdom - Germany - Spain - Austria - Netherlands - United Kingdom - Austria - Greece - Spain - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Higher or Secondary Education Establishments - - Smart Home (SH) provides a promising approach to assisted living for the ageing population. Yet it still remains a challenge to develop and deploy such solutions in a large scale due to the lack of an easy-to-use technology - infrastructure and application exemplars. This problem arises from the nature of the SH field: multidisciplinary, diverse in its applications, and with multiple stakeholders. Whilst a one-size-fits-all technology infrastructure seems unlikely, - alternatives are still missing. In addition, an effective approach to cross-discipline, cross-sector understanding for best practices has so far not been seen. - - - 2019-12-31, ongoing project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2015-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - ACROSSING - - - H2020-MSCA-ITN-2015 - - - 676157 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 246 668,40 - - - Linking the intrinsic protein dynamics to function in glutamate transporters - - - EUR 246 668,40 - - - France - - - Research Organisations - - The alternating access model of how membrane-embedded transport proteins translocate substrates across biological membranes has been proposed since the 1960s: membrane transporters bind substrates on one side of the membrane - and release them on the other side upon conformational rearrangements in the protein. This has been experimentally confirmed by high-resolution structures of membrane transporters in different conformations and is exemplified by the conformational - change in the archaeal glutamate transporter homologue GltPh from Pyrococcus horikoshii. GltPh is a trimer in which each protomer functions independently of the others. Outward and inward facing conformations suggest transport by alternating access - to either side of the membrane whereby a distinct transport domain undergoes large rotational and translational movements relative to the static trimerisation domain. It is unknown how GltPh achieves this conformational rearrangement, which occurs - both in the absence and presence of substrates. We propose to integrate cutting-edge techniques in membrane structural biology to identify dynamic hotspots that drive the large conformational transitions in GltPh. We will combine insights from - protein crystallography with local variations of thermodynamic stability and protein dynamics measured by hydrogen/deuterium exchange to map the structural components that allow conformational change to occur. In doing so, we will obtain new insights - into how GltPh functions, shedding light on the mechanism of biomedically important glutamate transporters. We will use this model system to develop strategies that allow understanding of the molecular basis of substrate transport. The methods - developed would be widely applicable to other membrane transport proteins. - - 2019-03-31, ongoing project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - France - - - MEMDYN - - - H2020-MSCA-IF-2014 - - - 660083 - - - - - INSTITUT CURIE - - - EUR 185 076 - - - In vivo analysis of neuromuscular junction stability in zebrafish models of amyotrophic lateral sclerosis - - - EUR 185 076 - - - France - - - Research Organisations - - Amyotrophic lateral sclerosis (ALS) is a late onset, lethal neurodegenerative disease of motor neurons that affects about 2 in 100,000 individuals per year. Different genetic mutations have been described in patients, but the - genes involved seem unrelated and the causes of the disease appear complex and are still largely not understood. Of relevance, the destabilisation of neuromuscular junctions (NMJ) may be an early event, preceding neuronal death, making them an - interesting therapeutic target to slow down disease progression. The goal of the study is to characterise the molecular organisation and dynamics of NMJ, in particular of cell adhesion molecules, in order to understand the mechanisms of maintenance - of NMJ by analysing defects in their organisation in ALS contexts. Technically, we plan to combine neuron biology, quantitative cell biology and computational tools to reach a precise molecular understanding of the dynamic equilibrium of NMJ in - zebrafish, an excellent vertebrate model for live imaging. We will develop innovative methods of super-resolution microscopy and of quantification of protein turnover using a fluorescent molecular clock. This precise molecular characterisation of the - NMJ will allow detecting subtle early changes in the NMJ that occur before neuronal degeneration starts, in fish carrying mutations described in ALS patients. The project will lead to the identification of key proteins for NMJ stabilisation and - enable the analysis of regulatory elements of this stability, especially the cytoskeleton. - - - 2017-11-15, closed project - - - 2015-11-16 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - NMJALS - - - H2020-MSCA-IF-2014 - - - 661527 - - - - - INSTITUT CURIE - INSTITUT CURIE - - - EUR 150 000 - - - DrugSynergy: A data-driven systems biology approach to optimize drug combination strategies - - - EUR 150 000 - - - France - France - - - Research Organisations - Research Organisations - - The complex physiopathology of human chronic diseases includes networks robustness, feedback loops, and cross-talks, which may induce limited efficacy, resistance, and/or excessive toxicity of an individual drug. Learning how - to combine drugs in order to improve treatment efficacy and lower undesired toxicity is a major biomedical challenge. Current strategies for drug repositioning and optimization of drug combinations have two man limitations: 1) they mostly use public - data and databases, which are based on knowledge of individual drug stimuli and do not specifically analyze interactions, 2) they consider limited number of cellular outputs to analyze the response to a drug. In DrugSynergy, we will use an innovative - systems biology large-scale data-driven approach to determine the interaction between two drugs at the highest possible resolution. Our computational analysis workflow has been extensively validated over the past years. It is now robust enough to be - applied for the optimization of drug combinations. - - 2018-02-28, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2015 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - France - - - DrugSynergy - - - ERC-2015-PoC - - - 680890 - - - - - INSTITUT CURIE - INSTITUT CURIE - - - EUR 150 000 - - - Epigenetic Profiling of Chemotherapy Efficacy - - - EUR 150 000 - - - France - France - - - Research Organisations - Research Organisations - - The aim of this proposal is to showcase that chromatin regulators represent a novel class of biomarkers that can predict the response to individual drugs. The proof of concept will be established by validating our recent - discovery of a 28-gene signature of chromatin regulators that predicts the response of 26 out of 31 patient-derived xenograft breast cancer models to docetaxel. Notably, in patients treated with docetaxel, though all are subjected to toxic side - effects, less than half of them clinically benefit, and no test exists to predict response. - - - 2017-04-30, closed project - - - 2015-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-PoC-2015 - ERC Proof of Concept Grant - - - ERC-POC - Proof of Concept Grant - - - France - - - EPOCH28 - - - ERC-2015-PoC - - - 678563 - - - - - AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS - - - EUR 239 191,20 - - - Elucidating the molecular basis of fruit resistance to desiccation: The cuticle as a key factor - - - EUR 239 191,20 - - - Spain - - - Research Organisations - - Water stress is a key environmental factor that causes important quality and economical losses before and after fruit harvest. As water depletion is becoming increasingly problematic, improving water efficiency and tolerance - of plants to dehydration is a priority of the European Union, as reflected in the societal challenge of Climate action, environment and resource efficiency. Likewise, food waste reduction is another key issue in the framework of Horizon 2020, as - described in Food security and sustainable agriculture and forestry challenge. Indeed, a large proportion of fresh produce is wasted during postharvest (25-50%) of horticultural crops, which is largely caused by dehydration. Therefore, this project - deals with the urgent need of understanding factors influencing water loss to develop innovative solutions geared to saving water and reducing food waste. Based on the idea that cuticular waxes are critical for limiting water loss from fruit, and - thus for resisting desiccation and spoilage, we propose to uncover the structural and regulatory pathways that mediate its biosynthesis, transport and assembly in response to drought stress through a multidisciplinary approach. Thus, SEM and TEM - microscopy, GC/MS, as well as up-to-date technologies, such as Laser Capture Microdissection (LCM) and RNA sequencing, will be used. Tomato and citrus fruit will be selected as model systems to address this poorly understood area of plant - biochemistry, physiology and molecular biology. The availability of mutants of both fruits, as well as the application of stress-related hormones during postharvest, will allow comparative surveys to better understand the regulation of these - processes. The outcomes of this proposal will represent a major advance in the understanding of the crosslink between water stress, wax metabolism and fruit biology, and will suggest strategies for enhancing shelf life, drought hardiness and fruit - quality in both climacteric and non-climacteric fruit. - - 2018-09-14, ongoing project - - - 2015-09-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Spain - - - 3F-FutureFreshFruit - - - H2020-MSCA-IF-2014 - - - 656127 - - - - - KOBENHAVNS UNIVERSITET - University of Calgary - - - EUR 263 719,80 - - - VIsual representations of VIew Relations to support effective data analysis on large and high-resolution displays - - - EUR 263 719,80 - - - Denmark - Canada - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - In VIVIR, I will conduct state-of-the-art research on supporting collaborative face-to-face data analysis. This is motivated by the increasing need for interdisciplinary teams to collaborate on understanding and analysing - data. Additionally, as the scale and complexity of data increase, so does the demand for data-based insights and decision-making. My approach is to empower people who are working with large and complex data, by letting them lay out as many - visualization views (in the following, denoted views) as necessary on large displays, and creating specialized meta-visualizations to show relations between these views. These meta-visualizations will allow team workers to be aware of each other’s - work and the changing view- and data-relationships as they work. While the potential of view meta-visualizations has been acknowledged , there are currently only a few frequently used and considered essential examples of such meta-visualizations. - These might show that data in two views are compared in a third view, or that a view shows a subset of the data shown in another view. Most importantly, there has been no thorough exploration into the power and potential of meta-visualization support - for data-driven decision-making. To understand the potential impact of meta-visualizations on data analysis, we need to take a structured approach, to formalize these possibilities, which will improve our abilities to support knowledge worker teams - as they face the challenges of analyzing increasingly complex data. - - 2020-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Denmark - - - VIVIR - - - H2020-MSCA-IF-2016 - - - 753816 - - - - - UNIVERSITA DEGLI STUDI DI PALERMO - THE UNIVERSITY OF NOTTINGHAM - INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE - UNIVERSITA DEGLI STUDI DI PERUGIA - BENAKI PHYTOPATHOLOGICAL INSTITUTE - UNIVERSITE DE MONTREAL - Agriculture and Agri-Food Canada - - - EUR 238 500 - - - Impact of invasive alien true bug species in native tropich webs - - - EUR 252 000 - - - Italy - United Kingdom - France - Italy - Greece - Canada - Canada - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - Insects can be accidentally introduced into non-native ecosystems by humans, or expand their geographical range toward the poles as a consequence of global warming. As they invade new environments, exotic species interact with - local species, modifying the structure of local food webs. New associations arising from with biological invasions can impact the strength of existing links with effects cascading through trophic levels. When invasive species are herbivores that can - attack economically important crops, they can cause serious economic losses. For example, recent invasion of the brown marmorated stink bug (BMSB) (Halyomorpha halys) in Europe and North America has the potential to interfere with local trophic webs - and poses a serious threat to several agro-ecosystems. - - - 2019-02-28, ongoing project - - - 2016-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - Italy - - - INVASIoN - - - H2020-MSCA-RISE-2015 - - - 690952 - - - - - OZYEGIN UNIVERSITESI - - - EUR 157 845,60 - - - A Collaborative Mobile Robot Arm that can Learn Impedance Critical Tasks from Humans - - - EUR 157 845,60 - - - Turkey - - - Higher or Secondary Education Establishments - - The aim of the proposed research is to develop a mobile manipulator that can effectively learn impedance critical tasks by means of physical interactions with a human, and acquire human’s abilities via human-to-robot skill - transfer for subsequent autonomous task execution. In a factory environment, execution of such tasks, e.g., drilling, screwing, are frequently encountered and can be easily accomplished by human workers. Nevertheless, automating these tasks with - robots require expert robotics engineering knowledge, robot-specific arrangements in the factory, and exact model of the environment. Through the integration of human-to-robot skill transfer techniques, these monotonous tasks can be autonomously - handled by a mobile manipulator so that human workers can focus on more complicated tasks. To this end, this project aims to develop required technologies to create such a system that can be actively used in a real factory environment for actual - scenarios. With the successful completion of the project, a crucial building block will be built for human-centered robotic automation, which is of importance in keeping the manufacturing jobs in EU. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Turkey - - - CoMRAde - - - H2020-MSCA-IF-2016 - - - 753219 - - - - - ELVESYS SAS - - - EUR 173 076 - - - A microfluidic chip for automating three-dimensional cell culture for personalized medicine - - - EUR 173 076 - - - France - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - A paradigm shift in health-care towards personalized medicine is slowly under way to tailor treatments to each unique individual’s needs. A key avenue for developing this field consists in recreating in vitro models of - specific body parts with cells. In particular, cells need to be placed in three-dimensions (3D) to truly recapitulate their normal environment in the body; yet current commercial assays only facilitate culture of cells in two-dimensions, which causes - cells to behave very differently thus distorting the results. Microfluidic technology is ripe for facilitating this transition, but does not offer any tool to facilitate the first essential step that consists in embedding cells in gels so that they - evolve in 3D inside the gel. To address this need, we propose a novel microfluidic platform that automates cell mixing with biological gels, that overcomes the challenge of mixing liquids with such different viscosities (i.e. gel and cells in - liquid), and offers precise temperature control to regulate the gel formation process. This novel tool will automate a tedious procedure that is normally done manually in the lab, which will accelerate the protocol and encourage a wider practice of - 3D cell culture, and guarantee the reproducibility of the gel formation around the cells. This project will enable both I and a start-up to acquire new skills in a cutting-edge field, thus driving European innovation. I will gain new expertise in - becoming an independent entrepreneur and in fabricating microfluidic tools, which will complement my pre-existing deep knowledge of biological microfluidic applications. This will enable me to transition from academia to industry, from the USA to - Europe, and commercialize on my own the many ideas I have been developing over my extensive career in academic research, while Elvesys who wants to enter the growing field of microfluidic cell culture, will gain an expert in 3D cell culture trained - in a world-renowned academic laboratory. - - 2020-01-07, ongoing project - - - 2018-01-08 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-SE - Society and Enterprise panel - - - France - - - TrueCell - - - H2020-MSCA-IF-2016 - - - 753785 - - - - - GUGER TECHNOLOGIES OG - - - EUR 178 156,80 - - - Movement restoration with Adaptive EEG And Immersive Neurofeedback - - - EUR 178 156,80 - - - Austria - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Despite very extensive efforts to help millions of people in the EU alone who seek therapy to improve motor function after a stroke, most stroke patients are left with lifelong motor disability. Recent work from our group and - others has shown that new methods and devices that can noninvasively monitor and stimulate brain activity could substantially improve recovery. EEG data collected from portable electrode caps can detect each patient’s motor imagery and thereby - influence multimodal feedback in real-time. This feedback may include virtual reality avatars, rewarding music or tones, functional electrical stimulation, and potentially even magnetic or electrical stimulation of motor areas of the cortex. This - promising new research direction requires extensive collaboration across disciplines and sectors, and experienced researchers (ERs) with relevant experience. The MoveAGAIN project will explore new classifiers, experimental paradigms, and software in - tandem with an existing commercial system to create a new system that will be used to collect data with stroke patients in two real-world settings. We will analyze the resulting data to develop new knowledge and contribute to improved tools that - therapists and physicians can use with patients. MoveAGAIN includes extensive dissemination and communication activities to convey our project results to numerous audiences. The varied training activities will supplement the ER’s training-by-research - to help prepare him for a high-impact career working across industrial, academic, and medical sectors. - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-SE - Society and Enterprise panel - - - Austria - - - MoveAGAIN - - - H2020-MSCA-IF-2016 - - - 752620 - - - - - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - - - EUR 183 454,80 - - - Decoding neural circuits controlling sleep drive and sedation - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Sleep and anaesthesia are both commonplace states that involve reversible loss of consciousness. However, the precise regulatory mechanisms underlying both still remain elusive, particularly at the circuitry level. Previous - studies suggest that sleep is homeostatically regulated and it has been proposed that the interaction between circadian rhythm and intrinsic sleep drive determines sleep status. Although much efforts have been made, the sleep field still lacks - clarity regarding the nature of the “sleep drive” as well as how it modulates sleep homeostasis. My host lab recently revealed that neuronal ensembles in the PO area, particularly in the lateral PO (LPO) area, a small region at the base of the brain - that contains a mixture of sleep-active, wake-active, and temperature-sensitive neurons, are selectively activated during recovery sleep and drug-induced sedation. These results indicate that the LPO neurons are able to sense the sleep drive. In this - proposal my goal is to identify LPO associated functional connectivity encoding sleep drive and sedation. By combining TetTagging functional ensembles of neurons with in vitro and in vivo optogenetics, electrophysiology and imaging techniques in - mouse, I aim to 1) evaluate alterations of excitatory/inhibitory inputs onto the defined LPO neurons during prolonged wakefulness and sedation; 2) identify the origin of inputs onto the defined LPO neurons; 3) tdetermine the effects of altered - connectivity involving active LPO neurons on sleep and sedation status in vivo. The results of the proposed research will provide novel insights into the regulatory mechanisms underlying sedation and the homeostatic drive of sleep. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - DNCSS - - - H2020-MSCA-IF-2016 - - - 753548 - - - - - THE UNIVERSITY OF SHEFFIELD - INSTITUT CURIE - TECHNISCHE UNIVERSITAET DRESDEN - UNIVERSITY COLLEGE LONDON - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - UNIVERSITA DEGLI STUDI DI PADOVA - FUNDACION CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III - JPK INSTRUMENTS AG - BIONCOTECH THERAPEUTICS SL - MIMETAS BV - - - EUR 3 911 897,16 - - - Biochemical and mechanochemical mechanisms in polarized cells - - - EUR 3 911 897,16 - - - United Kingdom - France - Germany - United Kingdom - United Kingdom - Italy - Spain - Germany - Spain - Netherlands - - - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - BIOPOL is an interdisciplinary European training network at the interface of cell biology, physics and engineering. BIOPOL aims specifically at the understanding of fundamental mechanochemical principles guiding cellular - behaviour and function and their relevance to human disease. A new supra-disciplinary research field is emerging bringing together the fields of molecular cell biology, physics and engineering aiming at an in depth understanding of fundamental - cellular mechanochemical principles. BIOPOL combines exactly this required expertise in one joint training program for young researchers. BIOPOL has assembled a unique multidisciplinary consortium bringing together top scientists from the fields of - molecular/developmental cell biology, membrane physics, engineering as well as specialists from the private sector. The scientific objectives focus on understanding of fundamental mechanisms of cellular mechanosensing in health and disease, the role - of external forces in cell division and mechanochemical regulation of cell polarity including tissue formation. Finally, part of BIOPOL´s research program is the further development of cutting edge technologies like advanced atomic force microscopy, - novel photonic tools like optical stretcher or innovative organ on a chip technology, exploiting physical cellular properties. BIOPOL´s collaborative cutting edge research program is integral part of its training program provided to early stage - researcher and is further translated into seven state of the art experimental training stations representing the consortiums expertise. In addition, BIOPOL has developed a 3 years modular curriculum including workshops, summerschools, Business plan - competitions and conferences with a specific agenda of transferable skill training elements highly relevant for scientific communication, translational research and in particular entrepreneurship. - - 2018-12-31, ongoing project - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - BIOPOL - - - H2020-MSCA-ITN-2014 - - - 641639 - - - - - UNIVERSITY OF GLASGOW - - - EUR 183 454,80 - - - Recombination-derived replication in the eukaryotic microbe Leishmania: a genome-wide process? - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - In any organism, the need to reproduce is paramount, with genome replication being the earliest step in the process. The machinery and mechanisms of DNA replication are widely conserved, with initiation occurring at defined - bi-directional DNA synthesis sites termed origins. Though origins may not be conserved DNA sequences, they are defined through binding conserved replication initiator factors. In some circumstances, such as after DNA damage or origin deletion, - origin-independent replication can be observed in cellular organisms and can be driven by recombination. However, origin-independent replication is not normally considered to be a genome-wide, central reaction of genome replication. Very recently, - genome-wide mapping of DNA replication initiation in two species of the kinetoplastid parasite Leishmania revealed only a single locus-specific origin per chromosome. Analyses of Leishmania S phase length and DNA synthesis speed suggest that a single - origin-based strategy is insufficient for complete genome duplication, indicating replication in these eukaryotic microbes relies on origin-independent initiation to support origin-directed initiation. In this proposal, I will test the hypothesis - that stochastic origin-independent DNA synthesis initiation events occur throughout the Leishmania genome due to homologous recombination acting on DNA lesions. If correct, this work will reveal the first example of a cellular organism that uses - origin-independent replication as a core feature of genome duplication. The genome-wide use of recombination-driven replication would alter our view of DNA replication evolution and would explain the remarkable genome plasticity of Leishmania, with - implications for how the parasite adapts genome structure and gene expression in the face of changing environments. Such adaptive change is seen during acquisition of resistance to anti-leishmanial drugs, and so this work will provide insight into - the use and development of therapies. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - RECREPEMLE - - - H2020-MSCA-IF-2016 - - - 750259 - - - - - SARMAP SA - - - EUR 175 419,60 - - - SaTEllyte synthetic Aperture radar interferometry to model Dam stabilitY - - - EUR 175 419,60 - - - Switzerland - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Analyses of surface deformation can help to define the evolution of areas, structures and infrastructures menaced by hazardous phenomena. To this end, space-borne Synthetic Aperture Radar (SAR) data provides direct measures of - surface movements. Specific techniques to handle SAR data have been recently applied to monitor not only natural hazardous phenomena, such as earthquakes, subsidence and landslides, but even structural health of buildings and infrastructure. The - large spread of these techniques is supported by the non-invasiveness of radar signals, the possibility to cover vast areas and the availability of a large database of data acquired since the ‘90s, despite they do not give any indication about the - triggering factors and the strain source or the tensile condition of a structure. STEADY Project (SaTEllyte synthetic Aperture radar interferometry to model Dam stability) is aimed to use SAR data to monitor dam structural health and, even more, to - apply an innovative approach, exploiting deformation fields as a starting point to re-create a simplified analytical model, providing preliminary hints about the stress-strain status of the dam in a short time if compared with traditional finite - element models. The relevance of this process emerges when environmental or logistic conditions do not allow to monitor dams through traditional geodetic and numerical techniques. In such cases, results obtained from SAR data combined with an - analytical model constitute a reliable diagnostic tool of dam structural health to avoid any extraordinary failure that may lead to loss of lives. The method will be tested on an emblematic real case, the Mosul dam, facing the following goals: (i) - analysis of satellite SAR data available over the area, (ii) identification of an analytical model to reproduce dam deformation behaviour and tensile condition, (iii) implementation of a semi-automatic tool to perform numerical simulations, - applicable to further cases. - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-SE - Society and Enterprise panel - - - Switzerland - - - STEADY - - - H2020-MSCA-IF-2016 - - - 752363 - - - - - KING'S COLLEGE LONDON - - - EUR 251 857,80 - - - Investigating the role of OPN-CD44 in mechanosensitive tumour invasion using biomimetic models - - - EUR 251 857,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - New fields are rapidly emerging that provide exciting and unforeseen opportunities to target disease. This is especially relevant for difficult-to-treat tumours where, despite decades of promising research, successful clinical - translation of therapeutic options remains intractable. The interrelated fields of mechanobiology and biomimetic engineered disease models have come to the fore in the last decade1–3 and provide a range of opportunities to investigate therapeutic - modalities4. These fields have implications for cancer research in three major aspects: 1) dissection of the cell biology governing microenvironmental sensing; 2) development of biomimetic platforms that enhance both the relevance (accuracy) of - experimental models and our understanding of tumour biology, especially at the level of microenvironment and cell signalling; and 3) creation of analysis tools to quantify cell sensing. In this MSCA Global Fellowship, I propose a formative advanced - research training period at one of the world’s leading institutions of cell and molecular biology and bioengineering (UCB) to learn and apply state-of-the-art biomimetic platforms for a novel tumour biology research project investigating - osteopontin(OPN)-CD44 in mechanosensitive glioblastoma invasion. This interdisciplinary collaboration will match the expertise of UCB in biomimetic tumour invasion modelling of the biomechanical and biochemical properties of glioblastoma with my - expertise in matricellular biology developed through my prior postdoctoral studies of osteopontin in liver disease. On my return to Europe at KCL, this will provide a springboard to establish an innovative independent research program in promising - and underinvestigated tumour biology. I will transfer the knowledge learned at UCB to establish to investigate hepatocellular carcinoma invasion with biomimetic models. This work will ultimately benefit the development of anti-invasive adjuvant - therapies. - - 2020-09-03, ongoing project - - - 2017-09-04 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - OPN-Can - - - H2020-MSCA-IF-2016 - - - 752097 - - - - - ASOCIACION BC3 BASQUE CENTRE FOR CLIMATE CHANGE - KLIMA ALDAKETA IKERGAI - UNIVERSITY OF OTAGO - - - EUR 233 276,40 - - - SAfeguarding Biodiversity and Ecosystem seRvices by integrating CULTURAL values in freshwater management: learning from Māori - - - EUR 233 276,40 - - - Spain - New Zealand - - - Research Organisations - Higher or Secondary Education Establishments - - Freshwater ecosystems are essential to people´s economic, cultural and social wellbeing, yet are still one of the most seriously threatened ecosystems on the planet. This conflict is reflected in political regulations that ask - to halt the loss of, restore and safeguard freshwaters, their biodiversity and the ecosystem services they provide. Ecosystem-Based Management (EBM), a holistic approach advocated to help doing so, involves an overarching regulatory framework and - local solutions with trade-offs and compromises - factors that make decision processes complex and easily co-opted. In SABER CULTURAL, we use a well-known participatory decision support framework (MCA) to tackle two major challenges in freshwater - EBM: 1) including cultural values that build a conceptual link between natural resources/biodiversity and local knowledge, besides traditionally considered ecological and socio-economic ones, and 2) accounting for uncertainty. MCA is selected because - it is i) transparent, ii) allows for the whole range of stakeholder values to be quantified and accounted for, iii) can be used to robustly test outcomes of different management scenarios, and iv) can ultimately be used to prioritise cost-effective - management actions with collective buy in. To forecast ecosystem services flow under different management alternatives, MCA is coupled with a novel modelling approach (ARIES). We test the MCA-ARIES framework in New Zealand, where cultural - Māori-values play a prominent role in freshwater management, and transfer the flow models to the river basin scale to inform existing management plans and policies in Europe. With SABER CULTURAL we establish new standards for freshwater management in - New Zealand, create knowledge that helps reaching EU biodiversity and environment targets and add value to the dialogue among EU policy sectors. Additionally, SABER CULTURAL provides a unique opportunity to gain the skills I need to become an - established, independent researcher in Europe. - - 2020-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Spain - - - SABER CULTURAL - - - H2020-MSCA-IF-2016 - - - 748625 - - - - - UNIVERSITA CA' FOSCARI VENEZIA - - - EUR 244 269 - - - A cultural history of comparative art practices and receptions in Cold War Europe (1945-1991) - - - EUR 244 269 - - - Italy - - - Higher or Secondary Education Establishments - - Cold War studies tend to emphasize dual narratives, mostly investigated as actions that are dictated from above by State policies or as cultural relations in an international context. Starting from my previous studies on - bilateral art relations in the second half of 20th century, the project is intended as a comparative survey within a polycentric and inclusive European focus area, including the two German republics, Yugoslavia, the Soviet Union and Italy. The main - study cases will be provided by multilateral art encounters and the involved locations and actors, analysed as individual and collective art practices. Unique Cold War art archives and collections at the Getty Research Institute and at the Wende - Museum in Los Angeles will provide key resources. In order to assess the impact of the art practices on culture and society, I intend to investigate both their critical reception in the professional art world and their popular response through the - commentaries left by exhibition visitors. A crucial question is whether the European dimension has ever been considered as a common ground - be it of political, social, artistic or speculative nature - for multilateral art practices within the - divided continent. Particular attention will be paid to unmet expectations and missed connections among the interested art communities. By including current Member and Associate States and Third Countries, the research is meant to contribute to - inter-European comprehension and integration, as an essential premise in order to “inform the reflection about present problems and help to find solutions for shaping Europe's future”, as stated in the Work programme 2016-2017 of Horizon 2020. The - project is conceived as a multidisciplinary research which, through training and inter-sectoral mobility in Comparative Studies, History and Art History, will have a ground-breaking impact on my future career prospects in the academic and - non-academic sectors as Comparative European Art Historian. - - 2021-01-07, ongoing project - - - 2018-01-08 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Italy - - - GYSIART - - - H2020-MSCA-IF-2016 - - - 750682 - - - - - UNIVERSITE D'AIX MARSEILLE - - - EUR 173 076 - - - Structure-activity relationships of an emerging family of fungal lytic polysaccharide monooxygenases - - - EUR 173 076 - - - France - - - Higher or Secondary Education Establishments - - During the past century, fossil-based hydrocarbons have been the main source of energy and chemicals, but in addition to be an unsustainable resource, they have led to important environmental concerns such as rising CO2 - emissions. The great challenge for our societies is to develop alternative approaches for the sustainable production of energy and materials; the bioconversion of lignocellulosic biomass is one of them. Nevertheless, the physical and chemical - recalcitrance of the biomass is the main obstacle to its cost-effective conversion as huge amounts of degrading enzymes are still required. Therefore, a significant improvement in enzymatic degradation is necessary, which involves enlarging the - catalytic toolbox. By doing a large scale screening of the secretomes of a substantial fungal collection, the host organisation has shed light on the first member of a new family of lytic polysaccharide mono-oxygenases (LPMOs). LPMOs have been shown - to boost the efficiency of cellulases industrial cocktails, thereby greatly reducing the financial and environmental penalties associated with the use of recalcitrant polysaccharides as a feedstock and, moreover, placing LPMOs at the center of - considerable research interest. The objective of the ARTFUL project is the functional and structural characterization of the representative members of the new fungal LPMO family. The 6 years’ experience of the French fellow in the glycobiology field - (biochemistry, enzymology, structural biology) combined with the expertise of Aix-Marseille University (France) in fungal omics form a solid basis that will be reinforce by the collaborations of experts. The quality of the hosting arrangements will - maximise the training opportunities of the fellow and is suited for the two way transfer of knowledge. Acquired generated knowledge will provide a robust functional context to bioinformatic-based predictive biology as well as new enzymatic tools for - subsequent industrial applications. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - ARTFUL - - - H2020-MSCA-IF-2016 - - - 748758 - - - - - BAY ZOLTAN ALKALMAZOTT KUTATASI KOZHASZNU NONPROFIT KFT. - REGIONALIS INFORMACIOS ES FEJLESZTO TUDASKOZPONT KORLATOLT FELELOSSEGU TARSASAG - HETFA KUTATOINTEZET - TUDOMANYOS ISMERETTERJESZTO TARSULAT - - - EUR 207 675 - - - Looking over the Horizon - horizontal priorities in research and in everyday challenges of the researchers' career! - - - EUR 207 675 - - - Hungary - Hungary - Hungary - Hungary - - - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - - Looking over the Horizon - horizontal priorities in research and in everyday challenges of the researchers' career! The main objective of “FAWORIT 2014-2015” is to overcome the prevailing stereotypes about researchers and - contribute to the enhancement of their public recognition through aspects of innovation, gender, mobility, international research and lifelong learning. We address the future generation and show the attractiveness of research career – with a special - awareness campaign with developing „SciMotion” with our industrial and school partners. We focus on the target group from the age of 5 to 24, but we aim to address all age groups with attractive programmes. The series of events at 20 locations will - focus on the Researcher through his/her career and the lively experiences of scientific life. The public will be “edutained” during the Nights: scientific presentations will be mixed with entertaining elements. There is going to be e.g. an „IQ - obstacle race”, an exhibition of researchers’ hobbies, a laser show and HiTech Pubs. The target audience can thus discover that the life of the researcher is fascinating, cool and attractive. Our objective is to have around 20,000 visitors at the - events, but a multiple of that number (around 500,000) will see, hear or read about the Nights. We are planning to raise awareness of the European engagement in R&D&I with the active participation of MC Fellows. In the European Corners and at - each venue related programmes of the European Union and the Marie Curie Actions will be visible. The structure of the consortium (stakeholders from academia and industry, from non-profit and for-profit organizations, with the contributing - participation of schools, a cluster, a multinational company and a media partner), the elaborated concept/workplan and the involvement of strategic media partners will guarantee the success of the project. We are also keen on to participate in the - celebration of the10th anniversary of Researchers’ Night. - - 2015-11-30, closed project | - - - 2014-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.5."> - - - MSCA-NIGHT-2014 - European Researchers' Night (NIGHT) - - - CSA - Coordination and support action - - - Hungary - - - FAWORIT 2014-2015 - - - H2020-MSCA-NIGHT-2014 - - - 633281 - - - - - STICHTING VU - - - EUR 165 598,80 - - - Who Should Have a Say? Preferences for Unequal Representation - - - EUR 165 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Equal representation is at the core of representative democracy, but are citizens actually in favour of it? There are good reasons to think that citizens may take a variety of stances toward unequal representation (i.e. - differential group influence over policy) particularly when it comes to groups that elicit strong emotional reactions (e.g. racialised minorities). Citizens may think that policy-affected groups deserve extra input (due to affectedness), less input - (due to bias), or the same amount of input as everyone else. However, it is impossible to say anything meaningful about these attitudes since we know almost nothing about them. This lack of knowledge is a serious shortcoming with real-world - implications: these preferences shape politics and, by extension, the functioning of representative democracies. My proposed study is thus relevant not only for recent debates in political science over both the extent and origins of unequal - representation, but also for contemporary politics – with its surging populist claims that certain groups have excessive influence over policy. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - UNREP - - - H2020-MSCA-IF-2016 - - - 750556 - - - - - CARDIFF UNIVERSITY - - - EUR 97 727,40 - - - Innate-Like T-Cells In Sepsis (ILTIS): Implications for Early Diagnosis and Rescue of Immune Suppression. - - - EUR 97 727,40 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Research on infectious diseases has high priority for the scientific and medical communities worldwide, to tackle the alarming spread of multidrug resistant bacteria and to fight and prevent virus outbreaks. On the French - island of La Réunion, infections such as leptospirosis and chikungunya pose considerable threats for public health. My career aspiration is to establish myself as a clinical scientist in the field of immunology of microbial infections, especially in - severe conditions such as septic shock and leptospirosis. I am also interested in deciphering the emerging role of host cell-derived factors (HSDF) in shaping the innate immune response. The immune response to pathogens and HSDF involves numerous - cell types and soluble factors such as cytokines but remains ill-characterized. A better understanding of the cellular and molecular signatures in acute disease may pave the way to better and earlier diagnosis, targeted treatment and improved - outcomes. - - - 2018-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ILTIS - - - H2020-MSCA-IF-2016 - - - 747278 - - - - - UNIVERSITA DEGLI STUDI DI FIRENZE - - - EUR 244 269 - - - TARGETING ENDOTHELIAL CELL AND CANCER AMOEBOID MOVEMENT TO OVERCOME RESISTANCE TO ANTI-VEGF AND ANTI-PROTEASE THERAPIES - - - EUR 244 269 - - - Italy - - - Higher or Secondary Education Establishments - - Unlike mesenchymal migration, the amoeboid motility doesn’t require proteases and is an opportunistic movement of cancer cells which allows cells to glide through, rather than degrade, ECM barriers, using movements based on - adaptations of the cell body. Preliminary experiments we conducted using a mixture of physiologic inhibitors of serine-proteases, metallo-proteases and cysteine-proteases, thus mimicking a physiological environment, showed no differences in vessel - formation for both Endothelial Progenitor Cells (EPCs) and mature Endothelial Cells (ECs) under mesenchymal or amoeboid conditions. Thus, we hypothesized the existence of an “amoeboid angiogenesis”. We also hypothesized that the failure of cancer - treatment using synthetic metalloproteinase inhibitors (MPIs) could be ascribed to the ability of cancer and ECs to skip the attack of the MPI therapy by allowing cancer invasion and blood vessel formation using the “amoeboid” strategy. Even the - VEGFA targeting partially disregarded the expectations because of the resistance onset followed by the progression of the disease. Our preliminary experiments showed also an “indifference” of ECs and EPCs to VEGF stimulation under amoeboid - conditions. Therefore, the aim of this project is to identify the multiple mechanisms shared by cancer cells and ECs/EPCs in the regulation of amoeboid movement, to identify common therapeutic strategies impairing vascular growth and cancer cell - invasion at the same time, overcoming resistance to anti-VEGF and anti-protease therapy. The molecules identified (ephrin, protease receptors, etc.) will be used as candidates for targeted therapy through the delivery of cargo liposomes containing - inhibitors of the connection of such molecules with the cortical actin cytoskeleton, in pre-clinical experiments with the perspective of a possible application to humans. We expect that this approach will give a progress in the treatment of tumors - thus improving outcomes for cancer patients. - - 2020-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Italy - - - ENDOCAM - - - H2020-MSCA-IF-2016 - - - 748731 - - - - - KARLSRUHER INSTITUT FUER TECHNOLOGIE - - - EUR 171 460,80 - - - Advanced Self-sorting and Supramolecular Polymers - - - EUR 171 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - The controlled formation of well organised self-assemblies within multicomponent supramolecular systems remains a challenge for modern chemistry. Herein, the aim of this project is to construct a constitutionally dynamic - library containing advanced supramolecular architectures (i.e. a molecular grid, a linear helicate and a macrocycle) through the combination of orthogonal self-assembly and self-sorting, then we intend to take advantage of the dynamic and orthogonal - interactions developed to synthesise doubly-dynamic main-chain and crosslinked metallo-supramolecular polymers. - - 2019-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - ASSP - - - H2020-MSCA-IF-2016 - - - 749351 - - - - - UNIVERSIDADE DO ALGARVE - - - EUR 160 635,60 - - - Characterizing the clinical relevance and the mechanism underlying TRIB2-mediated drug resistance to MEK inhibitiors in the context of melanoma - - - EUR 160 635,60 - - - Portugal - - - Higher or Secondary Education Establishments - - Melanoma is the most aggressive form of skin cancer resistant to all standard therapies. Currently, the established treatment of metastatic melanoma includes dacarbazine (DTIC) administration associated with response rates of - between 10-20% with severe side effects during treatment. Recently, the BRAF inhibitors (vemurafenib and dabrafenib) and the MEK inhibitor (trametinib) were approved for the treatment of melanoma patients with mutated BRAF (about 50% of patients) - while there are several PI3K, AKT, mTOR and MEK inhibitors being tested in clinical trials. However, the effectiveness of all these treatment modalities is limited by intrinsic or acquired resistance. The host lab has discovered a novel mechanism of - resistance to a broad spectrum of drugs in clinical trials/use for melanoma therapy mediated by the kinase-like protein TRIB2. This means that TRIB2 could be used as a biomarker to select melanoma patients for specific treatment options and to - develop co-treatment strategies to overcome drug resistance. This project pretends to (1) understand the mechanisms underlying TRIB2-mediated resistance to MEK inhibitors and to (2) further develop TRIB2 as a prognostic and predictive biomarker for - melanoma. Ultimately, the expected results will be highly relevant for the clinic as they might allow to select melanoma patients for specific treatment options and to develop co-treatment strategies to overcome TRIB2 mediate resistance. - - 2020-03-04, Grant Agreement signed - - - 2018-03-05 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Portugal - - - TRIBBLES - - - H2020-MSCA-IF-2016 - - - 748585 - - - - - UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA - - - EUR 170 121,60 - - - Novel RF Driven MRI Magnet for Imaging Enhancement - - - EUR 170 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - The key goals of the RF-MAFS project are: the training of the Experienced Researcher (ER) Dr. Javier Alonso-Valdesueiro, in the fast growing field of Scientific Instrumentation, where the host and partner institutions have - critical knowledge and expertise and the design, development and optimisation of a new Magnetic Resonance Imaging (MRI) machine based on the concept of Radio-Frequency Magic Angle Field Spinning (RF-MAFS). The aim of the research project is to design - and develop a novel type of portable MRI scanner which enhances the image resolution by applying a rotating magnetic field. This project brings together Engineering Skills, Magnetic Resonance (MR) Knowledge and Medical Imaging Insights. Therefore, it - will clearly have a broad positive impact on the European Research Area (ERA). The interdisciplinary and intersectoral training program includes specific training in RF power devices, magnet design and training in transfer of knowledge from academia - to industry. Then, it will enhance and broaden Dr. J. Alonso-Valdesueiro´s expertise in Applied Scientifc Instrumentation, increasing his exposure to both academia and industry. The Fellow is a talented researcher who has gained much expertise in - engineering applied to NMR during his postgraduate career. This background is of great value for the optimization magnet design for medical imaging. But for further boost his career, Javier needs to gain expertise in prototype construction for - scientific applications in which the University of Basque Country has a world-recognised expertise. Additionally, through the three-month secondment at University College London he will have contact with the medical image processing part of the - action. Therefore, The multidisciplinary project activities including outreach activities, supervision, and complimentary course outlined in the work plan, reflect all training objectives and will assist Javier in acquiring necessary competences and - reaching professional maturity. - - 2019-09-03, ongoing project - - - 2017-09-04 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - RF-MAFS - - - H2020-MSCA-IF-2016 - - - 750445 - - - - - ROYAL COLLEGE OF SURGEONS IN IRELAND - - - EUR 175 866 - - - Polyester/Polypeptide hybrid biomaterials for biomedical scaffolds - - - EUR 175 866 - - - Ireland - - - Higher or Secondary Education Establishments - - Next generation bioabsorbable and biocompatible polymeric biomaterials are key for the development of new medical devices and advanced approaches in healthcare with significant impact on applicable and affordable treatments - for EU citizens. EsterPep will bring together the expertise of the applicant in organo-catalytic synthesis of polyesters with the expertise of the host in synthetic polypeptides and medical applications with the objective to design a new class of - poly(ester-peptide) hybrid materials fully based on natural raw materials. The marriage of both systems promises novel functional, processible biomaterials with adaptable material and degradation properties not available from the individual building - blocks alone. The objective will be achieved in an interdisciplinary approach combining polymer chemistry and biomaterial science as well as the demonstration of processing feasibility into a biomedical scaffold for tissue engineering. The - workpackages have been designed to balance synthetic and application work as well as offering opportinities for intersectorial contacts to benefit the applicants experience. This project is ideally suited to the MSCA-IF programme as it provides - mobility and a nurturing, world-class environment for the applicant to embark on a future professional academic career. This will be achieved by developing relevant competences and skills supporting this career path combined with unique scientific - training in applied biomedical and biomaterial science guided by a tailored Career Development Plan. The dissemination of research results will target professional audiences as well as communicating to the general public through outreach activities. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Ireland - - - EsterPep - - - H2020-MSCA-IF-2016 - - - 748364 - - - - - UNIVERSITE DE BRETAGNE OCCIDENTALE - - - EUR 264 668,40 - - - Basin modes of the ocean: their role in the interannual to interdecadal climate variability - - - EUR 264 668,40 - - - France - - - Higher or Secondary Education Establishments - - Decadal climate predictions are a strong societal need for both EU and non-EU communities. However, mechanisms of low-frequency variability of the climate system remain unclear, preventing accurate prediction of decadal - climate changes. Several mechanisms have been proposed so far and they can be sorted in three categories: ocean only, atmospheric only and coupled dynamics. My project falls in the first category, focussing on the intrinsic variability of the ocean - forced by prescribed steady (or seasonally varying) atmospheric forcing. Because of the long memory of the ocean, recurrent patterns of oceanic variability, such as the oscillatory free basin modes, are the best candidates for decadal predictions of - the ocean-atmosphere system. However, our current understanding of the dynamics behind basin modes is low and urgent action is needed to improve it. An important question is whether these patterns can emerge above the noise level of stochastic - variability. One of my scientific hypotheses is that local baroclinic instability at high latitudes, in addition to wind-stress and surface buoyancy fluctuations, can excite robust global modes of oceanic variability. Objectives of my project consist - in increasing our knowledge of oceanic basin modes and assessing their relevance to decadal climate predictions. In the first part of the project, the dependence of the global modes on external parameters, such as bathymetry, model resolution, - coastlines and mean flow will be systematically studied in a step-by-step approach. In the second part, I will obtain the optimal forcing of the basin modes and its dependence on the external parameters cited above. In the third part, the basin modes - will be calculated in a realistic setting of the world ocean and rationalized in the light of what have been learnt in the first two parts. - - 2021-01-07, ongoing project - - - 2018-01-08 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - France - - - OceanModes - - - H2020-MSCA-IF-2016 - - - 749924 - - - - - UNIVERSITY OF LEEDS - - - EUR 183 454,80 - - - Geochemical Controls on the Ice Nucleating Efficiency of Volcanic Ash - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Ice formation in the atmosphere has a major impact on the properties and lifetime of clouds yet is one of the least well understood processes indirectly affecting the Earth’s climate. Heterogeneous ice nucleation by airborne - solid particles (‘ice nuclei’) exerts a profound influence on clouds by raising the temperature at which ice can form relative to by homogeneous freezing of supercooled water droplets. Volcanic ash from explosive eruptions is increasingly recognised - to be capable of acting as ice nuclei but factors determining the ash ice nucleating efficiency have yet to be elucidated. As for mineral dust from arid and semi-arid regions, physicochemical properties of the solid particles such as crystallinity, - mineralogy and composition likely play a role in their ice nucleating efficiency, but this remains poorly understood and has not been systematically investigated for volcanic ash. In addition, the influence of thermochemical processes/conditions in - the source magma, in the eruption plume and cloud, and in the ambient atmosphere on ash ice nucleating efficiency is not known. The proposed research will address this gap in knowledge through an experimental approach uniquely bridging volcanic - geochemistry and atmospheric science, to establish the link between ash ice nucleating efficiency and its physicochemical properties and magmatic, eruptive and atmospheric history. A range of natural ash and synthetic ash, generated and treated under - controlled laboratory conditions, will be studied. Experimental data will be parameterised for use in model simulations to predict regional ice nuclei concentrations based on an Icelandic eruption scenario. Collectively, the proposed research, - training and knowledge transfer activities will enhance the future prospects of both the Fellow and host, while contributing to the greater benefit of society by improving understanding of the potential impacts of ash emissions from explosive - eruptions on the atmosphere and on climate. - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - INoVA - - - H2020-MSCA-IF-2016 - - - 746695 - - - - - CENTRE INTERNACIONAL DE METODES NUMERICS EN ENGINYERIA - - - EUR 158 121,60 - - - Simulation of metal Solidification in Additive Manufacturing processes - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - The project is aimed to the enhancement of numerical simulation tools for the Additive Manufacturing process, focusing on analysis of temperature evolution and solidification behaviour of material during the Metal Deposition process. - - 2019-03-14, ongoing project - - - 2017-03-15 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - SimSolidAM - - - H2020-MSCA-IF-2016 - - - 746250 - - - - - ISTITUTO NAZIONALE DI FISICA NUCLEARE - - - EUR 180 277,20 - - - High Precision PDFs for the precision Era at the Large Hadron Collider - - - EUR 180 277,20 - - - Italy - - - Research Organisations - - High precision is the next frontier for the Large Hadron Collider (LHC). It requires accurate and precise theoretical predictions. The goal of this project is twofold: establish a statistically solid framework for estimating - the uncertainty on theoretical predictions, and producing more precise higher-order parton distribution functions (PDFs). - - 2019-10-31, ongoing project - - - 2017-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - HiPPiE_at_LHC - - - H2020-MSCA-IF-2016 - - - 746159 - - - - - WAGENINGEN UNIVERSITY - - - EUR 177 598,80 - - - The role of necrotrophic effectors in the ability of Botrytis and Monilinia species to infect host plants - - - EUR 177 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - Botrytis cinerea and Monilinia fructicola are both devastating pathogens that can cause decay in a broad range of hosts during pre and postharvest handling. Despite the current use of chemical fungicides, both fungal pathogens - are still responsible of important economic losses worldwide. The knowledge of pathogen virulence mechanisms is an important step to guide the search for new control strategies alternative to the fungicides currently in use. Crucially, the genome - sequences of both B. cinerea and M. fructicola can be exploited to identify genes and proteins that determine their ability to infect host plants. By applying molecular and bioinformatic analysis, NECROFUNGI aims to identify genes that encode - necrotrophic effector proteins which only kill their specific host, but do not affect other plant species. The identification of genes responsible for disease will lead the way towards new strategies to control plant diseases based on the development - of new classes of chemicals that are not directly toxic to fungi and to design more efficient breeding strategies. Wageningen University has an extraordinary resource to carry out this research. The host will train Dr. Vilanova in molecular and - bioinformatic techniques in the study of the B. cinerea and M. fructicola genomes, providing the necessary skills for her to establish a similar facility in her home country in the study of M. fructicola where none currently exists. In turn, the - fellow will bring specific expertise in postharvest fruit-pathogen interactions, not currently available at the host institution. The multidisciplinary perspective adopted, combining fruit-pathology, comparative genomics, molecular biology and - bioinformatics will build the necessary information to control these two devastating pathogens by effector-based technologies that would provide a great economic benefit for EU agriculture. - - 2020-02-29, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - NECROFUNGI - - - H2020-MSCA-IF-2016 - - - 741964 - - - - - UNIVERSITY OF LEEDS - UNIVERSITY OF LEEDS - - - EUR 1 258 250 - - - Seizing the Hybrid Areas of work by Re-presenting self-Employment - - - EUR 1 258 250 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - SHARE is a transdisciplinary and multi-method study of the work arrangements which destabilize the dichotomies between standard and non-standard work and between self-employment and dependent employment. More specifically, it - will research solo self-employment, namely self-employment without employees. This is a growing contractual category in Europe which comprises very different subjects, often disguised by statistics and difficult to represent by unions: from - independent professionals to ‘fake self-employed’ workers legally self-employed but in fact wholly dependent on the company. Therefore, I introduce the concept of ‘hybrid areas of work’ to refer to the co-existence of features usually attributed to - categories traditionally kept sharply distinct. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - SHARE - - - ERC-2016-STG - - - 715950 - - - - - EURECOM - EURECOM - - - EUR 1 978 777,83 - - - Theoretical Foundations of Memory Micro-Insertions in Wireless Communications - - - EUR 1 978 777,83 - - - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - We propose to develop the theoretical foundations of transforming memory into data rates, and to explore their practical ramifications in wireless communication networks. - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - France - - - DUALITY - - - ERC-2016-COG - - - 725929 - - - - - KING'S COLLEGE LONDON - - - EUR 195 454,80 - - - Quantitative brain network biomarkers for patient-specific diagnostics in idiopathic generalized epilepsy - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Epilepsies are common and highly disabling diseases characterised by recurrent seizures. They constitute a relevant health problem: ~2 million adults suffer from active epilepsy in Europe, leading to significant direct and - indirect costs (estimated to be ~14 billion euro (2010)). The scientific objective of this fellowship, to be carried out at the Division of Neuroscience at King's College London and the Centre of Predictive Modelling in Health Care of the University - of Exeter, is to develop a novel type of diagnostic biomarker for idiopathic generalised epilepsies (IGE), an important group of syndromes that affects 25-30% of patients, particularly young adults. This will be achieved by conducting a - cross-sectional case-control study that will use advanced quantitative neuroimaging techniques to measure alterations of brain network connections in IGE patients and healthy controls, and machine-learning algorithms to (1) classify patients with - different seizure types according to these alterations, (2) predict their seizure risk, as assessed with long-term electroencephalography (EEG), and (3) model the effect of network disruption on brain dynamics, using computational modelling. The - educational objective is to equip the fellow with the skills needed to become an independent clinical scientist in epileptology. This will be achieved through a comprehensive clinical and scientific teaching programme that will include: (1) part-time - participation in clinical rounds and clinical long-term EEG monitoring of complex epilepsy, (2) training in the neuroanatomy and quantitative measurement of white matter connections of the human brain,(3) training in computational neuroscience, and - (4) courses in scientific writing and project management. This programme is expected to broaden and diversify the fellow's skills, strengthen the ties between the cooperating research centers and yield novel insights that might help improve clinical - management of a highly relevant disease group. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - NETBIO-GE - - - H2020-MSCA-IF-2016 - - - 750884 - - - - - UNIVERSITA DEGLI STUDI DI PAVIA - UNIVERSITA DEGLI STUDI DI PAVIA - - - EUR 1 697 500 - - - deTeRmine the trUe dEpth of DeEp subduction from PiezobaromeTry on Host –inclusions Systems - - - EUR 1 697 500 - - - Italy - Italy - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Subduction of one tectonic plate below another is the primary cause of catastrophic geological events such as earthquakes and explosive volcanism that directly impact thousands of kilometers of coastal and mountain areas - located on convergent margins. Real-time geophysical or seismic data only provide static snapshots of these subduction zones today. Therefore, quantitative understanding of the rates and true depths of subduction can only be achieved by determining - the pressure-temperature-time-depth histories of Ultra-High-Pressure Metamorphic (UHPM) rocks that have been subducted to pressures greater than 3 GPa and subsequently exhumed. Conventional mineral thermo-barometry is severely challenged in UHPM - terraines and thus the mechanisms attending the downwards transport of crustal material, and its return back to the Earth’s surface (exhumation), are still a matter of vigorous debate. - - 2022-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-STG - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Italy - - - TRUE DEPTHS - - - ERC-2016-STG - - - 714936 - - - - - UNIVERSITAT AUTONOMA DE BARCELONA - - - EUR 170 121,60 - - - Labor Market Segmentation and Political Participation - - - EUR 170 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - Labor market segmentation is a defining feature of advanced industrial democracies. Workers experience different levels of labor risks and protections, with those in secure employment enjoying statutory entitlements and social - benefits while the low-paid, insecurely employed, underemployed and long-term unemployed do not. During the recent economic recession, the process of labor market segmentation has hastened, reaching unprecedented levels of differentiated labor risks. - Apart from the consequences of segmentation on social and economic inclusiveness and on long-term economic growth potential, segmentation has important but neglected implications for political inclusion and representation. LABOREP aims to fill this - gap by examining how labor market inequalities shape political mobilization. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - LABOREP - - - H2020-MSCA-IF-2016 - - - 742991 - - - - - AALTO-KORKEAKOULUSAATIO - - - EUR 179 325,60 - - - Cooper pair splitter based on Dirac materials - - - EUR 179 325,60 - - - Finland - - - Higher or Secondary Education Establishments - - Cooper pairs splitters (CPS) are promising candidate devices for solid-state sources of spin entanglement; a long-sought goal of outstanding impact in the development of quantum technologies. Recent experiments have reported - high splitting efficiencies but measurements can not resolve individual splitting events and are limited to time-averaged current and noise. - - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Finland - - - DiracEntangler - - - H2020-MSCA-IF-2016 - - - 743884 - - - - - HEINRICH-HEINE-UNIVERSITAET DUESSELDORF - HEINRICH-HEINE-UNIVERSITAET DUESSELDORF - - - EUR 1 995 890 - - - Tree rewriting grammars and the syntax-semantics interface:From grammar development to semantic parsing - - - EUR 1 995 890 - - - Germany - Germany - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The increasing amount of data available in our digital society is both a chance and a challenge for natural language processing. On the one hand, we have better possibilities than ever to extract and process meaning from - language data, and recent techniques, in particular deep learning methods, have achieved impressive results. On the other hand, linguistic research has a much broader empirical basis and can aim at rich quantitative models of language. Unfortunately, - theory and application interact too little in these areas of meaning extraction and grammar theory. Current semantic processing techniques do not sufficiently capture the complex structure of language while grammatical theory does not sufficiently - incorporate data-driven insights about language. - - - 2022-06-30, ongoing project - - - 2017-07-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Germany - - - TreeGraSP - - - ERC-2016-COG - - - 724411 - - - - - CENTRO DE ESTUDOS SOCIAIS - - - EUR 160 635,60 - - - Alternative Grassroots Organizations as a Response to Austerity: perspectives from Southern Europe - - - EUR 160 635,60 - - - Portugal - - - Research Organisations - - In recent years the global financial crisis and the consequent austerity measures have triggered protest movements all over the world. In Southern Europe there has been a strong wave of mobilizations directed to defend public - welfare provision. These anti-austerity movements have been characterized by a call for social justice framed in solidarity and inclusion, against the perception of a reduced capacity by the state of addressing citizens’ needs. This low level of - trust in institutional politics has triggered the creation of alternative spaces of deliberative and participatory democracy, directed to experiment with different political expressions. A crucial question is whether and how this claim for different - forms of democracy has been translated by social movements into organizational forms that bring increased democracy also into the economic sphere. In order to address this still underinvestigated issue, AGORA focuses on those entrepreneurial - activities that originate from the civil society, in this specific case as a direct expression of anti-austerity movements, that are characterized by the prevalence of social objectives over profit maximization. - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Portugal - - - AGORA - - - H2020-MSCA-IF-2016 - - - 747082 - - - - - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - - - EUR 171 460,80 - - - Hybrid Imaging of PET and PrOmpt gamma for preCision RAnge- and biological- guidance in proton ThErapy - - - EUR 171 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - Proton therapy is rapidly being established in the EU as a promising external beam tumour therapy modality offering an increased tumour-dose conformity with better sparing of critical organs and healthy tissue compared to - conventional photon therapy. However, full exploitation of its clinical potential is still hampered by non-negligible uncertainties during the treatment planning and delivery, posing the urgent demand of novel real-time techniques for in vivo - verification of the proton beam range. To this aim, the objective of this project proposal HIPPOCRATE (Hybrid Imaging of PET and PrOmpt gamma for preCision RAnge- and biological- guidance in proton ThErapy) is to explore the optimal design and - clinical potential of an innovative hybrid medical imaging approach that goes well beyond the state of the art, by combining real-time range verification from energetic prompt gammas with Positron-Emission-Tomography (PET) imaging of - irradiation-induced or externally injected tracers, to promote biological- and dose- guidance for personalized, high-precision proton therapy. By improving the quality of the rapidly emerging proton therapy modality, this project will promote longer - and healthier lives for cancer patients, with a high societal impact on the EU. Moreover, HIPPOCRATE can potentially go beyond the boundaries of medical imaging in proton therapy, by enabling high quality imaging of a whole new range of promising - unconventional radionuclides for diagnostic nuclear medicine imaging, as well as opening the perspective of biological image guidance at the radiotherapy treatment site, independent of the primary radiation quality. - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - HIPPOCRATE - - - H2020-MSCA-IF-2016 - - - 750689 - - - - - HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH - - - EUR 171 460,80 - - - Multifocal structured illumination optoacoustic microscopy - - - EUR 171 460,80 - - - Germany - - - Research Organisations - - Optoacoustic imaging is a highly scalable and versatile method that can be used for optical resolution microscopy (OR-OAM) at superficial depth yet can be adapted for tomographic imaging with ultrasonic resolution at - centimeter penetration scale. However, the imaging speed of OR-OAM is slow as far as concerned with acquisition of volumetric data, which greatly restricts its usage in applications involving dynamic biological processes. - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - MSIOAM - - - H2020-MSCA-IF-2016 - - - 746430 - - - - - KATHOLIEKE UNIVERSITEIT LEUVEN - - - EUR 160 800 - - - Synthesis of Spirooxindoles and INdoles pharmaceuticals using Metal-Organic Frameworks - - - EUR 160 800 - - - Belgium - - - Higher or Secondary Education Establishments - - SINMOF is a pioneering and structured effort to comprehensively address the introduction of different immobilised isolated catalytic active sites in solid hybrid materials to overcome the metal losses occurring with - state-of-the-art homogeneous catalysts employed in the pharmaceutical industry. The convenient use of hybrid metal-organic framework materials (MOFs) respect to traditional state-of-the-art porous solid materials is due to (a) - self-deactivation-resistant design of the active sites by (b) ultrastable catalytic site isolation. In the SINMOF project we will (1) design novel multifunctional MOFs as next generation catalysts for the synthesis of pharmaceutically active - compounds in an economically and environmentally beneficial way; (2) apply MOF hybrid solids as heterogeneous catalysts to avoid the use of homogeneous metal catalysts in novel synthetic strategies of pharmaceuticals with the indole core and finally - (3) derive structure-activity and selectivity relationships at the smallest possible length scales and with the highest possible sensitivities employing fluorescence microscopy. Using a two-stage research methodology, SINMOF will finally provide the - most active and stable MOF catalyst for the synthesis of the indole-based neurotransmitter Sumatriptan and the anticancerigen spirooxindole SAR405838. The combined expertise of the fellow and host ensures the best chance for successfully completing - the SINMOF objectives in a mutually beneficial manner. On one side, internal collaborations at the host institution will allow the access to state-of-the-art fluorescence microscopy methods, to get new insights into the molecular mechanisms - underlying the novel catalytic systems. On the other side, a secondment at a world-leading research center in the homogeneous catalysis field will train the researcher in order to individuate the best molecular features for model homogeneous - catalysts to be translated into selective heterogeneous MOF catalytic system. - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Belgium - - - SINMOF - - - H2020-MSCA-IF-2016 - - - 750391 - - - - - REGIONALIS INFORMACIOS ES FEJLESZTO TUDASKOZPONT KORLATOLT FELELOSSEGU TARSASAG - BAY ZOLTAN ALKALMAZOTT KUTATASI KOZHASZNU NONPROFIT KFT. - HETFA KUTATOINTEZET - TUDOMANYOS ISMERETTERJESZTO TARSULAT - - - EUR 207 675 - - - Fascinating World of Researchers in the Age of Technology 2016/2017 - The New Generation of Innovators - - - EUR 207 675 - - - Hungary - Hungary - Hungary - Hungary - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Other - - The main objective of our FAWORIT proposal is twofold: 1) to show the public how researchers with their innovative solutions affect our daily lives; 2) to encourage the youth – with a special focus on girls – to embark on - scientific careers by involving young innovators in our programmes. Our main target group is students between the age of 8-20, but we aim to address all age groups with attractive programmes. Some novelties of our project: offering challenge-oriented - activities – each of our 18 venues will present their innovative solutions related to interdisciplinary societal challenges; focussing on the concept of Responsible Research and Innovation - the audience will be informed about key elements of RRI, - thus creating better understanding and fostering future involvement; launching “Science in the City” – a flash mob like activity, involving the public in spectacular experiments. We will apply an integrated approach in our project in which - interdisciplinary challenges, innovative solutions, (young) researchers, their work and hobbies will be presented in an interactive, educating and entertaining way. The target audience can thus discover that being a researcher is cool and creative; - researchers, but and young innovators are amongst us. Our objective is to have around 30000 visitors at the events, but a multiple of that number (around 500000) will see, hear or read about the Night. We intend to raise awareness of the European - engagement in R&I; in the European Corners and at each venue related programmes of the European Union (FP7, H2020, especially MSCA) will be visible. The structure of the consortium: an innovative SME, a state-owned applied research institution, a - highly innovative large company, a scientific association with a broad network of local member institutions all over Hungary and an independent think tank established by economists and sociologists together with numerous contributing partners of all - kinds will ensure the success of the project. - - 2017-11-30, closed project - - - 2016-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.5."> - - - MSCA-NIGHT-2016 - European Researchers' Night - - - CSA - Coordination and support action - - - Hungary - - - FAWORIT 2016-2017 - - - H2020-MSCA-NIGHT-2016 - - - 722562 - - - - - KOBENHAVNS UNIVERSITET - - - EUR 212 194,80 - - - Travelling Sounds: A cultural analysis of sonic artefacts in postcolonial Europe - - - EUR 212 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - "In this postcolonial and globalised world, the movement and criss-crossing of people, ideas, and sonic artefacts across the boundaries of nation states have become integral to the everyday cultural practices of individuals - and groups. The vibrant connection between everyday cultural practices, artistic expressions, and new ways of thinking about culture in times of growing migratory movements and globalisation, has fascinated me ever since I started my PhD project on - South Asian British musical cultures in the context of postcolonial history and theory. Aiming at establishing myself as an independent scholar, and at taking my expertise in cultural studies, sound studies and postcolonial studies to the next level, - I am keen to study the postcolonial condition (Gilroy) of Europe not only through its musical, but also through its wider sonic cultures, taking into account sonic artefacts from different contexts, such as: sonic reinventions of urban space, the - social functions of mobile devices, and the identificatory power of sound in cultural memory and commemoration. The overall aim of this project is to establish a comparative perspective which includes case studies from Denmark and the UK, and to - investigate the cultural, social and political potential of sonic artefacts – music, voices, and everyday sounds – to forge a better understanding of Europe’s transcultural and entangled postcolonial histories and how they have shaped contemporary - sound cultures. To exemplify this, the project focuses on specific iconic events and artefacts such as the sonic-cultural politics of “Greenlandic Square” in Copenhagen, the postcolonial signature sound of the steel drum at Notting Hill Carnival in - London, and the 2011 so-called ""Blackberry riots"" addressing its use of social media networks for messaging, activist organisation and sonic representation. The challenging question when looking at these diverse examples is how they are connected - to Europe’s postcolonial condition." - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - TRAVELLING SOUNDS - - - H2020-MSCA-IF-2016 - - - 750199 - - - - - IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE - - - EUR 195 454,80 - - - Suppresion of adaptive immunity by the Salmonella effector SteD - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - In this project, I propose to characterize the influence of SteD, an effector of a globally important bacterial pathogen Salmonella enterica, on T cell development, and its potential therapeutic application. In the mouse model - of S. enterica infection, the onset of the specific immune responses is delayed significantly in comparison to other bacterial pathogens. Recent work by the group of Prof. Holden, who is the supervisor of this project, a world leader in the field of - Salmonella pathogenesis and the Director of the MRC Centre for Molecular Bacteriology and Infection (MRC-CMBI) at Imperial College London, identified SteD, an effector of the Type III Secretion System (T3SS) encoded by Salmonella pathogenicity island - 2 (SPI-2), as the first example of a virulence factor that reduces surface-localised mature Major Histocompatibility Complex class II (MHCII) levels in Dendritic Cells. In addition, I have found an increased activation of T cells following infection - of C57BL/6 mice with S. enterica serovar Typhimurium (STm) ΔsteD mutant in comparison to wild-type STm, thereby showing that SteD is an important modulator of adaptive immunity in vivo. SteD and/or its gene have a high chance of having therapeutic - application. I also have obtained preliminary evidence indicating that SteD has additional functions in the manipulation of antigen-presenting cells. Therefore, I propose to use both the acute and chronic mouse models of Salmonella infection to - further characterize the influence of SteD on T cell development. Furthermore, I will investigate the mechanistic and physiological significance of natural variation in the amino acid sequence of SteD among a broad range of S. enterica serovars, - including the typhoid fever-causing human-adapted serovars Typhi and Paratyphi. Finally, I will explore the possible use of SteD in new formulations of DNA vaccines. These studies will provide important knowledge for the clinical application of this - newly described T3SS effector. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SupaSteD - - - H2020-MSCA-IF-2016 - - - 747392 - - - - - KOBENHAVNS UNIVERSITET - - - EUR 200 194,80 - - - Investigation of aberrant DNA methylation in malignant haematopoiesis - - - EUR 200 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - Acute myeloid leukaemia (AML) is an aggressive type of blood cancer characterized by uncontrollable growth of immature myeloid cells. Somatic mutations in diverse transcriptional regulators result in aberrant epigenetic - landscape in leukemic cells, including patterns of DNA methylation. Due to its reversible nature, this epigenetic mark has been a promising therapeutic target and DNA methyltransferase inhibitors are already being used with varying degrees of success - in clinic. The targeted improvement of existing therapies requires a better understanding of mechanisms how altered DNA methylation promotes malignancies. TET2, an enzyme catalysing DNA demethylation, is one of the most frequently mutated epigenetic - regulators in AML. Its loss leads to hypermethylation at distal regulatory regions (or enhancers) and increased stem cell self-renewal and leukaemogenesis in the haematopoietic system. In the proposed work I plan to investigate the link between - aberrant hypermethylation at enhancers and its role in developing and maintaining AML. Firstly, I will take advantage of clinically relevant AML mouse models that combine TET2 deficiency with AML-specific alterations and annotate DNA - methylation-sensitive enhancers using high-throughput sequencing methods (MethylC-seq, ATAC-seq and ChIP-seq). Secondly, I will perform a positive-selection CRISPR-based high-throughput enhancer screen to identify DNA methylation-sensitive enhancers - that inhibit leukemic stem cell self-renewal (i.e. tumour suppressive regulatory regions). Finally, I will identify and study the function of transcription factors which binding is lost due to aberrant DNA hypermethylation at these sites. The - proposed work will be both discovery-based (genome-wide level) as well as mechanistic. - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - DNAmethAML - - - H2020-MSCA-IF-2016 - - - 749362 - - - - - KOBENHAVNS UNIVERSITET - - - EUR 212 194,80 - - - Riding to extinction: epigenomics of the Ice Age horses - - - EUR 212 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - The EPIRIDE project will use a combination of novel experimental and computational techniques to explore the role of epigenetics in long-term adaptive strategies of large vertebrates in response to rapid climate change. Modern - and ancient horse bone samples will be analysed for epigenetic markers using advanced high-throughput sequencing approaches, and the epigenomic landscapes will be contrasted over a 30,000-year record of major climatic and environmental shifts. - EPIRIDE has strong potential to reveal key genomic regions for climate adaptation in large herbivores, with considerable implications for conservation genetics and livestock management. - - 2019-12-31, Grant Agreement terminated - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - EPIRIDE - - - H2020-MSCA-IF-2016 - - - 748766 - - - - - CONSIGLIO NAZIONALE DELLE RICERCHE - - - EUR 180 277,20 - - - White Light Emitting Lanthanide Metal Complexes for Electroluminescent Materials - - - EUR 180 277,20 - - - Italy - - - Research Organisations - - There is an urgent need to develop a new generation of more efficient and durable illumination sources to surpass the limitations of the conventional lighting systems. Solid State Lighting sources based on Light Emitting - Diodes (LEDs) or Organic LEDs (OLEDs) devices are emerging as the next generation systems for general illumination. White LEDs on the market outperform the traditional incandescent and fluorescent lamps, both in term of efficiency and lifetime. More - work has still to be done to develop their organic counterpart, OLEDs. These offer the distinctive possibility to fabricate large area flat and also flexible devices by vacuum or solution processing, i.e. by potentially less expensive and less - energy-consuming production protocols. For this, the development of electroluminescent materials that show high brightness, easy synthesis, good chemical and electrical stability, low cost, and simple processing is actively pursued. In this context, - WHITELIGHT targets the development of single-molecule white light emitting materials for the fabrication of OLEDs, containing Eu(III) (red), Tb(III) (green) lanthanide ions and bis(2-pyridyl)amine based ligands (blue) emitters. This is a very - ambitious and multidisciplinary goal that requires a range of expertise spanning from theoretical chemistry to physical device fabrication and testing. The research unit at the hosting institution has a strong background in the photophysics of - materials for light/ energy conversion, complemented by an expertise in the design and synthesis of organic luminescent materials, as well as the fabrication and testing of electroluminescent devices. On the other hand, the Experienced Researcher has - a strong background in the synthesis of luminescent lanthanide complexes. This unique combination of expertise is a major factor for the successful implementation of the proposed research. - - 2020-01-01, ongoing project - - - 2018-01-02 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - WHITELIGHT - - - H2020-MSCA-IF-2016 - - - 749287 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 183 454,80 - - - Water management strategies and climate change in the Indus Civilisation - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - WaMStrIn will re-evaluate the relationship between human settlement and the changing hydrological network of the Indus area of Pakistan during the emergence of first urban centres in ancient South Asia (2500-1900 BC). The - ancient Indus was the most extensive of the three so-called cradles of Old World civilisation and a number of attempts have been made to trace the network of palaeorivers that watered this region and sustained its ancient population. Using a novel - combination of multi-temporal satellite remote sensing, GIS-based topographic analysis, geostatistics and network analysis WaMStrIn will overcome previous problems in the detection of ancient rivers and associated archaeological sites. In doing so - WaMStrIn will provide new hypotheses and quantifiable open access data on (1) past water management, (2) the mechanism employed to cope with changing water availability and (3) the consequences of a long-term shift towards more arid conditions for - South Asia's earliest large-scale, urban, and interconnected society. - - 2020-01-01, ongoing project - - - 2018-01-02 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - WaMStrIn - - - H2020-MSCA-IF-2016 - - - 746446 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 195 454,80 - - - Plotting the material flows of commonplace Late Bronze Age Seals in Western Eurasia - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The aim of PLOMAT, an innovative project on Commonplace Seals of Late Bronze Age Western Eurasia, is to offer new perspectives on the study of non-élite populations and the small-scale networks that operated at a time of art - internationalization in the ancient world. PLOMAT will map the flows of materials and ideas in the Late Bronze Age by studying cylinder seals, which were an important and widely used class of object. Combining Digital Humanities and scientific - material analysis with innovative archaeological and art historical theories, it will study for the first time the production and consumption of ‘commonplace’ cylinder seals in mid-second millennium BCE, which spread over a wide area from the Eastern - Mediterranean to Central Western Asia. Seemingly produced en-masse on ‘low-cost’ materials, these artefacts represent an ideal subject for studying the flow of ideas across large areas in the ancient world. By developing and implementing novel - computational methods and material analysis, and engaging with a bottom-up social archaeological approach, it will chart movements of people and ideas throughout East and West, provide for the first time a clear large volume of material analysis - characterization, explore the appropriation and/or rejection of Mesopotamian material and visual culture and unveil elements of non-élite history of the region and its peoples. In addition to numerous essential transferable skills invaluable to the - future world-class researcher and academic, PLOMAT will provide training in GIS and spatial analysis, exploratory multivariate statistics and X-ray fluorescence analysis of materials using Bruker Portable XRF Spectrometers. The expertise of senior - researchers at the University of Cambridge, combined with available resources and facilities make it the ideal organisation to host the project and ER. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - PLOMAT - - - H2020-MSCA-IF-2016 - - - 748293 - - - - - KATHOLIEKE UNIVERSITEIT LEUVEN - - - EUR 172 800 - - - Designing Novel Efficient Catalytic Strategies for the Transformation of Lignocellulose into Lignin-derived Chemicals and Valorisable Carbohydrates - - - EUR 172 800 - - - Belgium - - - Higher or Secondary Education Establishments - - The utilization of renewable lignocellulose biomass (composed of cellulose, hemicellulose and lignin) alternative to fossil fuels is crucial for long-term economic and social stability. In this context, the catalytic reductive - lignocellulose fractionation (CRLF) process has received tremendous research interest as this strategy enables one-pot conversion of lignocellulose into useful lignin-derived chemicals, while retaining a solid (hemi)cellulose fraction that can be - used for the production of fuels, chemicals or paper. The development of promising heterogeneous catalysts having abundant redox and acid properties, along with the application of a proper solvent is a great challenge for efficient CRLF process. - - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Belgium - - - CATLIGCAR - - - H2020-MSCA-IF-2016 - - - 747968 - - - - - LUNDS UNIVERSITET - - - EUR 185 857,20 - - - Assessment of African Vegetation Resources: New Perspectives from Satellite Passive Microwave Datasets - - - EUR 185 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - Livelihoods of most of the African population strongly depend on local ecosystem services, such as grazing, agriculture, firewood, and construction timber. Although an overall greening trend is shown by both dynamic global - vegetation models (DGVMs) and Earth Observation (EO), large uncertainties for each data source are reported and significant divergence between outputs have been documented, impeding accurate assessment of vegetation dynamics in Africa. The overall - purpose of this project is to develop methods to for an improved assessment of African vegetation resources based on new capabilities originating from satellite passive microwave observations. Specifically, the vegetation optical depth (VOD) derived - from passive microwave data is sensitive to the water content in both the green and woody (i.e., branches and stems) vegetation components which is different from the traditional optical-infrared greenness driven vegetation index (VI) being primarily - sensitive to chlorophyll abundance. By combining multi-frequency VOD retrievals with long-term VI datasets, in situ measurements, and DGVMs, this project will accurately quantify woody biomass, green biomass, net primary production (NPP), vegetation - phenology and ecosystem functional types (EFT) in Africa, as well as their long-term changes and the climate and socio-economic drivers. The results are expected to pave the road for improved vegetation resource management in Africa and understanding - of global carbon cycling. To achieve this, I will be trained in cutting edge skills (EO time series, flux measurements and ecosystem modeling). My major mobility activity will be sparking the integration of passive microwave VOD, carbon and water - flux measurements and DGVMs for an improved understanding of changes in vegetation resources and drivers hereof in Africa. - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - AfriVeg - - - H2020-MSCA-IF-2016 - - - 746347 - - - - - UNIVERSITE CATHOLIQUE DE LOUVAIN - - - EUR 160 800 - - - Multi-layered biomimetics of lytic polysaccharide monooxygenases - - - EUR 160 800 - - - Belgium - - - Higher or Secondary Education Establishments - - The high stability of components like cellulose limit the efficiency and cost effectiveness of biofuel or chemical production from lignocellulosic biomass. Thus, the ability of the recently discovered class of metalloenzymes, - lytic polysaccharide monooxygenases (LPMO), to enhance the efficiency of recalcitrant polysaccharide degradation makes understanding these enzymes invaluable for carbon friendly sustainable chemical and energy development as prioritized under the - Horizon2020 program. - - - 2020-01-07, ongoing project - - - 2018-01-08 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Belgium - - - MOMIMIC - - - H2020-MSCA-IF-2016 - - - 753953 - - - - - UNIVERSITY OF SOUTHAMPTON - - - EUR 195 454,80 - - - Art and Ethics: Restarting and Advancing a Stalled Debate - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - This project is a work of philosophy that investigates how intrinsic ethical properties are realized in artworks and other aesthetic and creative objects and practices, and in what respects their aesthetic values are - determined by these properties. The project innovates in three principal ways. First, it identifies and articulates novel ways by which artworks and similar objects and practices come to exhibit ethical properties, where the existing literature in - this area relies exclusively on just one way this can occur. Second, it diagnoses why the literature on the question of ethico-aesthetic value interaction has stagnated for almost a decade, by revealing the vague and inconsistent conceptual tools on - which its theorists have relied until now, and which have inhibited its progress. Finally, it uses the preceding two innovations to articulate a new and satisfactory theory about how ethical properties determine aesthetic values. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - United Kingdom - - - Art and Ethics - - - H2020-MSCA-IF-2016 - - - 750848 - - - - - UNIVERSITEIT GENT - - - EUR 258 530,40 - - - Multitasking Nanoparticles for Intracellular Bioimaging and Biosensing - - - EUR 258 530,40 - - - Belgium - - - Higher or Secondary Education Establishments - - The development of specifically designed nanomaterials for advanced medical applications such as theranostics has become a major technical challenge with great potential societal and economic outcomes. Nanomedicine and related - techniques hold great promises for improved diagnostic and treatment of widely spread diseases such as cancer. This project, entitled NanoIntra, aims at developing novel multitasking nanoparticles as advanced tools for highly localized and - ultrasensitive intracellular imaging and biosensing. These nanoprobes should provide new insights in the spatial and temporal processes at play in live cells and therefore reveal part of their mystery. Such functional objects are achieved through the - design of a complex architecture which involves quantum dots as bright and stable luminescent markers encapsulated in a protective silica matrix. These nanoparticles are combined with plasmonic nanocrystals, which offer new strategies for their - photothermally induced intracellular delivery. The targeting and imaging of specific subcellular structures is then achieved thanks to proper surface functionalization of the nanoparticles. In addition, the plasmonic nanocrystals also allow these - nanoparticles to be used as Surface Enhanced Raman Scattering (SERS) biosensors. Finally, for a higher control on the use of such nano-biosensors, optical tweezers are used to purposefully manipulate and position the nanoparticles inside the cells at - the region of interest. Besides their application in cell labeling and biosensing, these functional nanoparticles have tremendous potential applications in the fields of theranostics, nanomedicine and nanobiophotonics, and NanoIntra constitutes a - first step toward the development of a full lab-on-a-particle. Thus, through the synthesis and characterization of novel materials and their application to biotechnology, NanoIntra is a multidisciplinary research and training project at the interface - between physics, chemistry and biology. - - 2020-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) - - - MSCA-IF-GF - Global Fellowships - - - Belgium - - - NanoIntra - - - H2020-MSCA-IF-2015 - - - 702300 - - - - - THE UNIVERSITY OF EDINBURGH - - - EUR 183 454,80 - - - Integrated drug discovery approach to generate brain-penetrant inhibitors of glioblastoma cell proliferation - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Glioblastoma multiforme (GBM) is the most common and aggressive cancer that begins within the brain. Without treatment the average survival following diagnosis is merely 3 months. Although clinically-approved kinase inhibitors - present promising features to treat GBM, most of them do not cross the blood brain barrier (BBB), impeding their clinical use in GBM patients. We propose an agile approach that combines ligand-based drug design of highly-focused compound libraries - and first-in-class phenotypic assay for simultaneous screening of BBB penetration, unspecific toxicity and anticancer properties, in an iterative manner. This approach will allow a one-step selection of hit / lead compounds from in-house generated - compound libraries that cross the BBB to accelerate the design of CNS-active anticancer drugs. Furthermore, the use of chemical proteomics and the state-of-the-art proteomics techniques will facilitate the identification of the kinases and / or - pathways that are involved in the observed phenotype, which could result in the discovery of novel GBM oncotargets and unknown modes of action. This highly innovative integrated approach has the potential to speed up preclinical drug discovery - efforts in CNS diseases, and in doing so, promote European Scientific Excellence. As a developer and provider of such tools, the applicant will be positioned in a privileged position for starting cross-disciplinary collaborations with academics and - Pharma across Europe and for establishing herself as an independent researcher. - - 2020-02-29, Grant Agreement signed - - - 2018-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - BRAINHIB - - - H2020-MSCA-IF-2016 - - - 749299 - - - - - SYDDANSK UNIVERSITET - - - EUR 200 194,80 - - - COULD SENESCENCE BE ADAPTIVE? CAUSES AND CONSEQUENCES OF AGING ACROSS THE TREE OF LIFE - - - EUR 200 194,80 - - - Denmark - - - Higher or Secondary Education Establishments - - Why do organisms age? This is surely one of the most compelling questions in biology. With advancing age, organisms can see physiological decline leading to higher mortality and lower fertility, a process known as - ‘senescence’. The foundations of aging research state senescence should be inevitable in any organism, and is likely a by-product of attenuation in force of selection with age. But is senescence inevitable? Could senescence be adaptive? - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Denmark - - - WHYAGE - - - H2020-MSCA-IF-2016 - - - 746235 - - - - - UNIVERSITY OF DURHAM - - - EUR 195 454,80 - - - Isotopic evidence for diet and mobility during the Neolithic transition to farming in the Near East - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The Neolithic transition represents perhaps the most significant development in human history. In Europe the ‘Neolithic package’ arrived as a whole, and has been studied in detail using isotopic and genetic methods, but few - isotopic studies have addressed the earlier and more complex transition in the Near East. Thus currently we know little about the changes in diet and mobility of individuals and cannot compare this crucial region to the later transition in Europe or - to parallel transitions elsewhere. ISONEO will investigate the composition of diet in selected Neolithic populations of the Near East using carbon and nitrogen isotope analysis. Using strontium and oxygen isotopes in human tooth enamel ISONEO will - explore the importance of migration in creating and sustaining the population of Pre-Pottery Neolithic B megasites and in the lifeways of the desert populations of the Pottery Neolithic and Chalcolithic in Jordan, Israel, and NW Saudi Arabia. The - main sites used will be ’Ain Ghazal, Basta, Ba’ja, Kharaysin, Mallaha, Beisamoun, and Shubayqa. The results will be used to build a regional model of the diet, mobility and social changes that took place during the Neolithic transition in the Near - East in a holistic synthesis with previous research based on traditional archaeological evidence including archaeobotany and archaeozoology. The Experienced Researcher, Dr Jonathan Santana will be supervised and trained by Dr Andrew Millard. Within - the research intensive context of the Department of Archaeology at Durham he will enhance and expand his existing research skills, knowledge of practical techniques, and theoretical knowledge. He will be trained in stable isotope analysis and the - interpretation of isotopic data, which will enable him to undertake the research for ISONEO. These new competencies will enhance his skills in scientific methods and critical thinking applied to archaeology and will increase his prospects for - obtaining a permanent academic position. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ISONEO - - - H2020-MSCA-IF-2016 - - - 750460 - - - - - THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN - - - EUR 175 866 - - - Firescape genomics: predicting plant responses to changing fire regimes - - - EUR 175 866 - - - Ireland - - - Higher or Secondary Education Establishments - - Increases in the frequency of wildfire driven by invasive plant species, land use change and climate change are occurring globally. The current mismatch between past and present fire regimes means we have little ability to - predict how, or if, ecosystems will adapt to these novel pressures. However, many European plant species have been introduced into Australia where fire frequency exceeds levels found in the species native range. My project, hosted by Trinity College - Dublin and supervised by Professor Yvonne Buckley, will capitalise on this unique opportunity to predict how species will respond to increases in fire frequency that are occurring in Europe under climate change. I have already produced an existing - genomic database from hundreds of individuals across fire frequency gradients in Australia. The task now is to strategically sample areas of Europe to establish the native baseline and use cutting-edge spatial analyses to investigate the phenotypic - and genomic basis underlying adaptation to changing fire regimes in European plant species. My Training Plan includes specific professional development programs to enhance my critical skills in leadership, grant writing, teaching and global - networking. During the fellowship, I will improve essential competencies needed to compete at ERC-level including mastering sophisticated analytical and bioinformatics tools. My interdisciplinary research, drawing together population ecology, - invasive species management and landscape genomics will make a critical contribution to the European Climate Action priority to anticipate and minimise damage caused by climate change. Following my strong track record in science communication, I will - disseminate my work widely to the scientific community, end-users and to the general public at the broadest level. The prestigious Marie Skłodowska-Curie fellowship will allow me to develop the professional maturity to establish myself among the - leaders of the European research community. - - 2019-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Ireland - - - FIRESCAPE - - - H2020-MSCA-IF-2016 - - - 746191 - - - - - UNIVERSITE LIBRE DE BRUXELLES - - - EUR 240 530,40 - - - Tools to Carve out Conformal Field Theories - - - EUR 240 530,40 - - - Belgium - - - Higher or Secondary Education Establishments - - Recently a number of research efforts have been dedicated to the conformal bootstrap. The basic principle is that conformal symmetry and quantum mechanics should suffice to fix uniquely the dynamics of Conformal Field Theories - (CFTs), which lie at the fixed points of the renormalisation group flow. This has led to ground-breaking results, such as the unprecedented determination of scaling dimensions in non-trivial CFTs including the celebrated Ising model in 3d. Thus far - these endeavours have focused only on the simplest examples of correlation functions with low-spin operators or to supersymmetric CFTs. - - 2020-09-24, ongoing project - - - 2017-09-25 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Belgium - - - TcCFT - - - H2020-MSCA-IF-2016 - - - 747228 - - - - - FUNDACAO CALOUSTE GULBENKIAN - - - EUR 148 635,60 - - - Dissection of the mechanisms causing the epistasis between antibiotic resistance mutations in Escherichia coli - - - EUR 148 635,60 - - - Portugal - - - Research Organisations - - Antibiotic resistance is a major threat to public health. Bacteria can become resistant by acquiring genes that counteract the action of antibiotics or by mutation of their targets. These targets are usually involved in - essential processes and typically resistance mutations can impair bacterial growth in absence of antibiotics. However, combination of certain mutated alleles can result in an alleviation of this cost, thus favouring the acquisition of multiple - resistances. This project aims to understand the mechanisms underlying the epistasis between resistance mutations. Decreased biosynthesis has been considered the main cause of the fitness cost associated to antibiotic resistance mutations. However, - our preliminary results suggest the existence of additional causes, such as genomic instability or proteostasis imbalance. The study of these phenotypes in single and double resistant mutants of Escherichia coli will allow us to determine the nature - of these epistatic interactions, as well as further understanding essential biological processes, and will provide information for the development of new treatments against multi-resistant infections. - - 2020-11-30, Grant Agreement signed - - - 2018-12-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Portugal - - - ResistEpist - - - H2020-MSCA-IF-2016 - - - 746690 - - - - - UNIVERSITE DE RENNES I - - - EUR 185 076 - - - MEMBRANE PROTEINS OF ELECTROACTIVE BACTERIA PROBED AT LIPID LAYERS ONTO MODIFIED ELECTRODES - - - EUR 185 076 - - - France - - - Higher or Secondary Education Establishments - - MELBA aims at developing an efficient and versatile electrochemical platform for probing the charge transfer properties, electronic or protonic, of membrane proteins extracted from Gram negative electroactive bacteria. This 2 - years research project will be conducted at the Université de Rennes 1, UR1 France, including a six months Secondment at Universidade Nova de Lisboa, UNL Portugal. Carbon electrodes will be covalently modified with pH-responsive electrophores through - surface modification techniques, WP1 Task1. Lipid layers will be deposited onto the modified electrodes to create an artificial membrane as a host for extracted membrane proteins, WP1 Task2. The experienced researcher Dr. Lebègue will learn protein - expression, extraction, purification and characterization during the six months Secondment at UNL, WP2 Task3. Finally extracted proteins will be incorporated into the artificial membrane deposited onto the modified electrodes and their electronic - and/or protonic charge transfer properties will be characterized, WP2 Task4. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - MELBA - - - H2020-MSCA-IF-2016 - - - 745689 - - - - - FUNDACIO PRIVADA INSTITUT CATALA D'INVESTIGACIO QUIMICA - - - EUR 170 121,60 - - - Photocatalysis induced by copper complexes supported on Silica materials-Study in Flow processes - - - EUR 170 121,60 - - - Spain - - - Research Organisations - - PhoCuS-Flow project aims to contribute to the European Research Area (ERA) by developing a new generation of sunlight activated copper photocatalysts supported on mesoporous silica. Three novel concepts are proposed: i) use of - tris(triazolyl)methanol-Cu-complexes (developed in the host group) as photocatalysts in organic reactions, ii) the immobilization of the complexes on mesoporous silica materials to be used as heterogeneous and recyclable catalysts and iii) - implementation of a continuous flow setup in order to gain in efficiency and potential industrial applicability. These objectives have a direct impact in some of the ‘Societal Challenges’ listed in H2020 i.e. ‘Secure, Clean and Efficient Energy’ and - ‘Climate action, Environment, Resource Efficiency and Raw Materials’. - - 2020-04-30, Grant Agreement signed - - - 2018-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - PhoCuS-Flow - - - H2020-MSCA-IF-2016 - - - 746190 - - - - - UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA - - - EUR 158 121,60 - - - Ironworking technology and social complexity of rural comunities during the Early Medieval Ages - - - EUR 158 121,60 - - - Spain - - - Higher or Secondary Education Establishments - - The application of scientific techniques to analyse archaeological materials has greatly influenced modern archaeology, providing archaeologists with the tools to generate datasets, such as those associated with chronological - dating and chemical compositions, from which more rigorous interpretations can be developed. The Basquesmith project aims to investigate ironworking production during Early Medieval (EM) times by applying microscopic techniques on an assemblage of - materials excavated in rural settlements in the Basque Country (northern Spain), a region renowned for the superior quality of its iron products. Characterisation of the manufacture and repair methods used, the quality of the utensils produced, and - the debris generated, will provide valuable insight into which production occurred at the sites. The originality lies in the artefacts themselves as well as the archaeometallurgical approach to investigate these assemblages. Common utensils such as - ladles or keys made from iron, which are exceptionally rare in EM rural contexts, allow ironworking to be explored on rural implements from rural communities rather than prestige items from urban contexts. This will result in a truly utilitarian - project combining history, archaeology and materials science to investigate a much neglected area for EM Spain. Basquesmith is highly committed to EU's strategy endorsed in the field of Cultural Heritage and is in an excellent position to carry out - this research through the promotion of such an interdisciplinary approach. Moreover, Basquesmith integrates the applicant’s knowledge in material science with a top level research group (GIPyPAC) at the University of Basque Country. This network will - not only encourage dissemination of the research within the academic literature and spotlight the cultural heritage of the Basque region, but it will also provide a framework which can be applied to the evaluation of technology in rural communities - at other archaeological sites. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - Basquesmith - - - H2020-MSCA-IF-2016 - - - 746058 - - - - - BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION - - - EUR 170 121,60 - - - Seasonal Prediction of Fire danger using Statistical and Dynamical models - - - EUR 170 121,60 - - - Spain - - - Research Organisations - - Wildfires have a great impact on the environment and can pose a threat to property and human lives and health. The occurrence of fire in natural vegetation is dependent on human activities and climate variability. In tropical - areas such as the Amazon basin and Indonesia, wildfires are greatly affected by inter-annual fluctuations in tropical Sea Surface Temperatures (SSTs). During the El Niño events of 1997-1998 and 2015-2016, uncontrolled wildfires caused record impacts - on health, transportation and the economy. The European countries of the Mediterranean basin are frequently plagued by drought episodes (e.g. during the summer of 2016), causing dangerous wildfires which result in deaths, health problems and economic - losses. - - 2019-09-05, ongoing project - - - 2017-09-06 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - SPFireSD - - - H2020-MSCA-IF-2016 - - - 748750 - - - - - VIB - - - EUR 160 800 - - - IgA-based oral therapy for protection of piglets against infection with enterotoxigenic E. coli. - - - EUR 160 800 - - - Belgium - - - Research Organisations - - Postweaning diarrhoea (PWD) in pigs is responsible for important economic losses in the global pig rearing industry. This illness is predominantly caused by enterotoxigenic E. coli strains carrying the F4 (ETEC-F4) and F18 - (ETEC-F18) fimbriae. There is no treatment available to fight PWD except using antibiotics. However, the prophylactic use of antibiotics is forbidden in Europe and is expected to become forbidden in the rest of the world because of increasing - abundance of resistance genes. Delivery of sIgA to mucosal surfaces as passive immunotherapy agent is a very promising strategy to prolong maternal lactogenic immunity against post-weaning infections. The aim of this project is to produce sIgA-like - anti-ETEC antibodies in a cost-effective platform. Twenty different anti ETEC-F18 antibodies in a sIgA-like format will be engineered from phage display-selected variable domains (VHHs) currently available in the host institute. The synergistic or - additive neutralisation effect of oligoclonal antibody cocktails will be evaluated using ETEC-F18 in vitro villus adhesion assays. The different antibodies will be produced first by transient expression in Nicotiana benthamiana and second in seeds of - Arabidopsis thaliana transformants. An in vivo ETEC-F18 challenge will then be performed using two groups of piglets, one receiving the most effective seed-derived feed formulations and the other one receiving regular feed (negative control group). - The sIgA antibodies of the elite oligoclonal formulation will then be transferred to biosafe soya seeds as production platform. These steps will lead towards the development of scalable procedures to obtain a cost effective bulk production of a feed - based prophylaxis against ETEC. - - 2017-04-30, closed project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Belgium - - - ImmunoFarm - - - H2020-MSCA-IF-2014 - - - 658701 - - - - - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS - - - EUR 185 076 - - - Covalent-ligation-assisted elucidation of protein-aromatic foldamer interactions - - - EUR 185 076 - - - France - - - Research Organisations - - The development of ligands that selectively bind to a given protein surface is a challenging area of research with potential applications in diagnostics, pharmacology or therapy. Current approaches include small molecule - screening, the design of medium sized epitope mimetics (e.g. alpha helix mimetics) and directed evolution methodologies (e.g. ribosome display). - - 2019-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - PROFOLIG - - - H2020-MSCA-IF-2016 - - - 751019 - - - - - OSASEN SENSORES S.L. - - - EUR 158 121,60 - - - A Low-cost disposAble eleCTrochemical biOsensor for Point Of Care (POC) hypolactasia diagnostic testing - - - EUR 158 121,60 - - - Spain - - - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - LACTOPOC is a multidisciplinary research and training programme targeted to provide Dr. Macia-Gonzalez, an expert in electrochemical analytical platforms design, with new entrepreneurial and scientific skills on translation of - innovative biosensor technology into Point of Care (POC) diagnostic devices. - - 2019-05-01, ongoing project - - - 2017-05-02 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-SE - Society and Enterprise panel - - - Spain - - - LACTOPOC - - - H2020-MSCA-IF-2016 - - - 749368 - - - - - UNIVERSITY OF BRISTOL - - - EUR 183 454,80 - - - Developing the Next Generation Framework for Testing Nonlinear Dynamic Structures. - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - When designing new structures and devices, engineers are completely dependent on mathematical models to ensure that their designs function as intended. As technological boundaries are pushed to the limits, systems become - nonlinear – the response of the system is no longer proportional to the input. These nonlinear systems can exhibit a wide range of complicated behaviour that is very difficult to predict and potentially disastrous. Take for example the F-117A Night - Hawk stealth jet. Despite extensive modelling and design work, at an airshow in 1997 in Maryland, Essex, USA, it encountered a disastrous instability known as flutter. The aircraft was lost. - - - 2018-04-30, Grant Agreement terminated - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - TNS - - - H2020-MSCA-IF-2015 - - - 703204 - - - - - HERIOT-WATT UNIVERSITY - - - EUR 195 454,80 - - - Highly Disruptive and Compact Antenna Systems for Small Satellites with Application to Surveillance, Environmental and Crop-Growth Analysis, Enabling European Union Dominance in the Space Industry - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Compact satellites are transforming space-based surveillance systems. Typical configurations include a network of small satellites that can offer increased coverage and enhanced data collection rates when compared to - conventional large scale systems. Microsatellites can also drastically reduce launching costs and mission development time, thus making remote sensing technologies more cost effective. Applications include vehicle tracking, weather monitoring, - maritime surveillance, crop growth analysis, and climate change observation. However, with satellite miniaturization, new design aspects arise. All satellite components have to be cleverly packaged within a small payload and materials must - accommodate the harsh operating environments of space. - - - 2018-12-31, ongoing project - - - 2017-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - CSA-EU - - - H2020-MSCA-IF-2015 - - - 709372 - - - - - QUEEN MARY UNIVERSITY OF LONDON - QUEEN MARY UNIVERSITY OF LONDON - TEL AVIV UNIVERSITY - - - EUR 991 750 - - - Spectral theory of random operators - - - EUR 991 750 - - - United Kingdom - United Kingdom - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The theme of this proposal is the study of random operators associated with some geometric structure, and the influence of the geometry on the spectral properties of the operator. Such operators appear in problems from - theoretical physics, and lead to new and interesting mathematical structures. - - 2020-05-31, ongoing project - - - 2015-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2014 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - United Kingdom - - - SPECTRUM - - - ERC-2014-STG - - - 639305 - - - - - ASSOCIATION GENETHON - - - EUR 185 076 - - - Correction of duplications in the DMD gene by a CRISPR/Cas9 approach - - - EUR 185 076 - - - France - - - Research Organisations - - Duchenne muscular dystrophy is an X-linked recessive muscle-wasting disease, characterized by progressive weakening of skeletal, respiratory, and cardiac muscle followed by necrosis and fibrosis. DMD affects ~1:3,500 live male - births and is associated with delayed motor milestones. DMD occurs as a result of mutations within the DMD gene that lead to premature termination of translation. The most frequent type of mutations are exonic deletions and duplications that induce a - frame-shift in the protein-coding sequence. To date no effective treatment exist for this disorder. - - 2019-02-28, ongoing project - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - DMD2CURE - - - H2020-MSCA-IF-2015 - - - 703093 - - - - - TECHNISCHE UNIVERSITAET WIEN - - - EUR 178 156,80 - - - Slow-Fast Systems in Cellular Biology - - - EUR 178 156,80 - - - Austria - - - Higher or Secondary Education Establishments - - Mathematical modelling has emerged as an important tool to handle the structural complexity of cellular processes and to gain better understanding of their functioning and dynamics. We propose to develop methods for the - mathematical analysis of ODE models arising in cell biology. We focus on models of great biomedical importance, i.e. cell division cycle, NF-kB signalling pathway, and the p53 system. Pertinent mathematical questions of biological interest are: - existence and stability of equilibria, periodic oscillations, switching phenomena, and bifurcations. - - 2018-08-29, ongoing project - - - 2016-08-30 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Austria - - - SFSysCellBio - - - H2020-MSCA-IF-2014 - - - 661650 - - - - - CENTRE EUROPEEN DE RECHERCHE EN BIOLOGIE ET MEDECINE - - - EUR 173 076 - - - “Quantitative analysis of the molecular and cellular behaviors associated with cardiac valve morphogenesis in pathological and regenerative contexts” - - - EUR 173 076 - - - France - - - Research Organisations - - Cardiovascular diseases (CVDs) take a huge toll on the world population. An estimated 19 million people died from CVDs in 2010, representing 30% of all global deaths. Abnormal blood circulation is widely recognized as a - cardiovascular risk factor and mechanotransduction has been shown to trigger pathologies such as atherosclerosis1, cardiomyopathies2 and valvulopathies3. Mechanotransduction is the conversion of a mechanical stimulus into a biological response. It is - central to the coordination between mechanical forces generated by flowing blood and heart valve morphogenesis. In the developing heart, the heartbeat and the blood flow signal to endocardial cell (EdC) progenitors through mechanosensitive proteins - which in turn modulate the genetic program controlling cardiogenesis4. It is essential to determine how mechanical forces control pathway activation and morphogenesis in vivo because the mechanical stimuli experienced by EdCs are too complex to be - faithfully reproduced in vitro. This timely proposal aims to uncover the cellular molecular programs activated in EdCs in response to mechanical forces during normal heart valve development and address their potential function in valve regeneration. - My hypothesis is that endocardial mechanotransduction and mechanical forces are not only key for the morphogenesis of the valve, but also for their maintenance and repair. Specifically I aim to investigate the spatial and temporal nature of - endocardial cellular behaviors necessary for cardiac valve morphogenesis in normal, pathological and regenerative contexts. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - France - - - ZEBRA-VALVE - - - H2020-MSCA-IF-2015 - - - 708312 - - - - - FUNDACIO PRIVADA INSTITUT CATALA DE PALEOECOLOGIA HUMANA I EVOLUCIO SOCIAL - - - EUR 158 121,60 - - - Integrative Approaches to Dental Wear: Non-Masticatory Tooth-Use Across the Mesolithic-Neolithic Transition Among Iberian Foraging and Farming Societies - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - The IDENTITIES project investigates human dental wear related to the non-masticatory use of the dentition (the habitual use of “teeth-as-tools”) among human groups that span the Mesolithic-Neolithic Transition in the Iberian - Peninsula – a period of complex social, economic, and technological reorganization corresponding to a shift from hunting and gathering to a dependence on domesticated plants and animals. A lifetime of using the teeth for habitual, manipulative tasks - leaves distinct traces on enamel, and these idiosyncratic patterns of wear provide biocultural markers of social identities when aligned with information on sex, age, occupation, or status of individuals across archaeological samples. Human dental - remains from archaeological sites across the Iberia provide an ideal regional focus for exploring biocultural changes related to tooth-use during a crucial prehistoric socioeconomic transition. IDENTITIES is interdisciplinary, bringing together - experts in microscopy, experimental methods, bio/archaeology, and paleoanthropology through an integrative methodology to document non-masticatory dental wear. The methodologies include recent advances in Gigapixel-like imaging strategies, confocal - and scanning electron microscopy, and three-dimensional dental topographic methods to analyze experimentally-worn and archaeological samples. The integrative methodology was also established to cross-validate each method (presently an unresolved - issue), and advance the study of material surface modification of biological and archaeological materials generally. In addition to providing an intellectual impact through methodological advances, the same data will directly address how biocultural - changes in non-masticatory tooth-use reflect changing social identities across archaeological groups of the last foraging peoples (Mesolithic), nascent farming societies (Neolithic), and established agriculturalists (Chalcolithic) in the Iberian - Peninsula. - - 2019-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - IDENTITIES - - - H2020-MSCA-IF-2016 - - - 749188 - - - - - FUNDACIO CENTRE DE REGULACIO GENOMICA - - - EUR 158 121,60 - - - Functional dissection of core spliceosomal mutations causing Retinitis Pigmentosa. - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - More than 95% of human genes undergo pre-mRNA splicing, and alternative splicing of mRNA precursors represents a prevalent mode of gene regulation. Errors in this process are often the origin of of disorders. Most of - splicing-related diseases are caused by perturbation in pre-mRNA transcripts which lead to their aberrant processing. Interestingly, a fraction of mutations affecting directly splicing factors, including core spliceosomal components, has been linked - to a group of pathologies. Particularly intriguing are variants of the key spliceosomal subcomplex U4/5/6 tri-snRNP, associated with Retinitis Pigmentosa. Why these mutations lead to highly tissue-specific phenotypes, rather than general toxicity - cause by a global block in splicing, remain unexplained. The proposed research aims to increase our understanding of the molecular mechanisms underlying the effects of these mutations and shed light on the basis of the disease. To functionally - dissect these variants, I will combine spliceosomal network approaches (I) with genome-wide transcriptome analysis (II) and detailed biochemical and structural studies (III). Mechanistic insights derived from these analyses will help to identify - transcripts that are predominantly sensitive to these mutations and that could be behind their pathogenic effects (IV). This work will allow us to better understand the function of key splicing factors, as well as the basis for their effects on - splice site selection and their contributions to Retinitis Pigmentosa pathology. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - SpliceCore - - - H2020-MSCA-IF-2016 - - - 747488 - - - - - UNIVERSITY OF CYPRUS - - - EUR 221 446,80 - - - 'Sharing without Solidarity: Politics, Heritage and Pilgrimage in a Divided European Society' - - - EUR 221 446,80 - - - Cyprus - - - Higher or Secondary Education Establishments - - The proposed project will explore how religion, politics and heritage intersect in a deeply divided European society, by examining the Christian-Orthodox shrine of Apostle Andreas, in the Turkish-occupied Karpass peninsula - (Cyprus). The shrine is mainly visited by Greek-Cypriots and to a lesser degree by Turkish-Cypriots, and it is currently being restored by both communities with the involvement of the EU. Using semi-structured interviews with pilgrims and officials - involved in the shrine’s management and restoration, participant observation, and visual and archival research material, the study will look at (a) the attempts to restore the shrine, and (b) the revival of pilgrimages in conditions of ongoing - division. The initial aim is to uncover symbolic, cultural, ethnic and political associations ascribed to the shrine and the pilgrimage by local and international actors. Examination of the shrine is also a powerful means through which to access past - and present aspects of intercommunal relations. One original dimension of the proposed project is that it is one of the very few to study the institution of pilgrimage as a whole, looking at pilgrims, organizers, political actors and international - organizations. This all-round perspective is appropriate to an analytical approach that, unusually, does not take religious motivation to be the default motivation for participation in the workings of a shrine, and it is necessary as a means of - seeing whether and how different stakeholders articulate with each other in a situation of ongoing tension. This model of ‘articulation’ is intended to transcend simple dichotomies evident in the anthropological literature between ‘communitas’ - (fellowship) and contestation in the operation of a shrine. Focusing on a pilgrimage site that is located in a divided country that is a member of the EU, the project has the potential to inform EU policy on heritage and conflict resolution, while - benefiting the communities under study. - - 2020-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Cyprus - - - T.A.MA - - - H2020-MSCA-IF-2016 - - - 752103 - - - - - UNIVERSITY OF DURHAM - - - EUR 195 454,80 - - - Testing the role of thermo-chemical piles in the generation and continuation of plate tectonics - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The mechanics of plate tectonics (the movement of the Earth's surface) is a fundamental scientific question in understanding the recycling of mantle volatiles in processes that affect habitability. The emergence of plate - tectonics on Earth set the planet apart from others in our solar system allowing for the propagation of life, yet the fundamentals of how it all began remain unresolved. Present-day geophysical imaging of the deep mantle show anomalous chemical piles - thought to originate from the beginnings of Earth. Recently, consensus has been reached that the chemical piles can impact, and be impacted by, plate tectonic processes. However, their interaction with mantle convection in a pre-plate tectonic early - Earth is not well known. In this study, state of the art numerical experiments will be designed and implemented to offer the first investigation into what role deep chemical heterogeneities play in the initial breaking of the lithosphere (to initiate - a form of plate tectonics). Furthermore, a numerical analysis into the evolution of temperature and mantle dynamics in the early Earth will be conducted to assess a range of geodynamic scenarios previously hypothesized. This fellowship is timely as - it complements a number of recent developments in early Earth tectonics, numerical modelling, and in knowledge of thermo-chemical pile behaviour. - - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - United Kingdom - - - TEROPPLATE - - - H2020-MSCA-IF-2016 - - - 749664 - - - - - CHALMERS TEKNISKA HOEGSKOLA AB - - - EUR 185 857,20 - - - Innovative FRET-based toolkit for screening of drugs to fight miRNA-related diseases and its use in the development of cancer treatment with miRNA-96 as a therapeutic target - - - EUR 185 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - The overall goal of this project is to develop a universal FRET-based toolkit for screening of drugs targeting microRNA (miRNA). Specific outcome will be a high-throughput assay for finding drugs targeting miRNA-96, a - tumor-suppressing miRNA in pancreatic cancer cells. FRET is the technique of choice and recently, Prof. Marcus Wilhelmsson, Chalmers University of Technology (CHALMERS; project main supervisor) pioneered the development and photophysical - characterization of fluorescent base analogues (FBAs) optimized for high-resolution FRET analysis of nucleic acid systems. There is an urgent need in pharmaceutical industry for an in vitro, cell-free, pre-miRNA-small molecule interaction - high-throughput assay and also to increase the understanding of the nature of miRNAs. In this project, the unique FRET FBAs will be utilized to develop such assays and to provide new knowledge regarding miRNA structure, dynamics and interactions with - other biological molecules or drugs. Apart from taking on the new research field stated above and developing my professional skills, I will bring in new competences to CHALMERS in RNA biochemistry (from the University of Warsaw and Max Planck - Institute in Göttingen). Moreover, as part of my training, I will carry out research at AstraZeneca (AZ) and Gothenburg University (UGOT) through secondments. CHALMERS/AZ/UGOT have an established collaboration and I will take full advantage of their - R&T capacities in order to gain interdisciplinary and intersectoral expertise as well as to master my skills in scientific communication, scientific writing, coordinating research projects, results exploitation, critical assessment, mentoring, - supervision, presentation and networking with other researchers across the globe. This MSCA Postdoctoral Fellowship will help me reaching a position of professional maturity invaluable for starting up my own research group or taking leading roles in - industrial R&D organizations. - - 2020-08-31, Grant Agreement signed - - - 2018-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - DrugSearchTool - - - H2020-MSCA-IF-2016 - - - 753595 - - - - - UNIVERSITE PARIS DESCARTES - - - EUR 246 668,40 - - - Next gEneration Sequence sTORage - - - EUR 246 668,40 - - - France - - - Higher or Secondary Education Establishments - - Sequential data are everywhere, from DNA sequences to astronomical light curves, and from aircraft engine monitoring data to the prices of stock options. Recent advances in various fields such as those of data storage, - networking and sensing technologies, have allowed organizations to gather overwhelming amounts of sequential data at unprecedented speeds. - - 2020-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - France - - - NESTOR - - - H2020-MSCA-IF-2016 - - - 748945 - - - - - KUNGLIGA TEKNISKA HOEGSKOLAN - - - EUR 173 857,20 - - - Excellent lung cancer imaging and tumour identification using next generation computed tomography - - - EUR 173 857,20 - - - Sweden - - - Higher or Secondary Education Establishments - - Lung cancer has the highest incidence and mortality rates of all cancers, and patient survival is strongly linked to early detection. Therefore, low-dose CT screening of high-risk individuals, the only method proven to improve - survival, is now recommended by major health organisations. There are, however, concerns with the high rate of false positives and increased radiation exposure associated with screening. We propose to investigate the clinical benefits of spectral CT - for lung nodule detection and characterisation. The unique, photon-counting, spectral silicon detector developed by the host group offer twice the resolution, no lower dose limit, reduced artefacts, and higher contrast sensitivity than current - state-of-the-art. Our hypothesis is that the patient dose can be significantly reduced in both the detection and characterisation steps, and that the higher resolution will reduce false positives. The reduction in screening dose alone would prevent - an estimated 15 cases of induced cancer per 10,000 individuals screened. Fewer false positives would then further reduce the dose through fewer follow-ups and characterisations, lower clinical costs and workload, and reduce patient distress. The - fellowship would allow the researcher to benefit from the world-class research, close ties to commercial partners and strong international collaborations of the host, and the exceptional clinical expertise of the partner organisation. In particular, - training in cutting-edge detector technology, novel image reconstruction techniques and management of patient studies would complement the researcher’s strong background in medical physics and image analysis. The training, expected high-impact - research and networking opportunities will strongly enhance the career prospects of the researcher, the outreach activities will give public awareness of the potential of spectral CT, and the expected clinical gain will benefit society at large, in - particular future lung cancer patients. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Sweden - - - EXCITING-CT - - - H2020-MSCA-IF-2016 - - - 750564 - - - - - NATURAL HISTORY MUSEUM - - - EUR 195 454,80 - - - Evolution of the Cochlea and Hearing in Odontocetes - - - EUR 195 454,80 - - - United Kingdom - - - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - Toothed whales (Odontoceti) are a spectacular example of evolutionary adaptation, highly specialised apex predators and a key component of modern ocean ecosystems. The key innovation that has facilitated their evolutionary - success is echolocation. Research into odontocete hearing has so far been biased towards physiological experiments and auditory pathway identification; quantitative studies on the cochlea are lacking, despite its critical role in audition. I will - fill this gap in knowledge of the cochlea in cetaceans by: (1) quantifying differences in the morphology of odontocete cochlea through the application of cutting-edge scanning, visualisation and quantitative analytical techniques (e.g. 3D geometric - morphometrics) to gather in depth data of all features of a fully representative range of odontocete cochlea; (2) testing through statistical analysis whether these differences correlate with, or are driven by, factors such as diet, behaviour or - auditory sensitivity; (3) incorporating fossil taxa to pinpoint the timing of the evolution of echolocation; and (4) identifying convergent evolution of specialised high frequency hearing in river dolphins using novel methods for testing and - quantifying morphological convergence. This project will create the most comprehensive data set of odontocete inner ear models ever compiled and will mark a major advance in the understanding of cetacean sensory evolution, providing profound insights - into how this enigmatic group of marine mammals came to dominate the oceans - making sense of a sixth sense. The data gathered will be made openly available to other researchers. - - 2019-10-01, ongoing project - - - 2017-10-02 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ECHO - - - H2020-MSCA-IF-2016 - - - 748167 - - - - - WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER - - - EUR 159 460,80 - - - Saline Fluids in the Mantle - Experimental Investigation of Their Role in Diamond Formation and Kimberlite Magmatism - - - EUR 159 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - The majority of natural diamonds that have great economic importance for the gem industry are formed at great depth beneath old continents in the subcontinental lithospheric mantle (SCLM). The main carrier of these diamonds - are kimberlites, deep volcanic rocks that transport fragments of the SCLM to the Earth’s surface. Both diamond formation and kimberlite genesis are still heavily debated processes in the Geosciences. Growing evidence from natural samples, such as - fluid inclusions in diamonds, suggests that chloride-bearing fluids may play an important role in diamond formation and possibly in kimberlite generation. These saline fluids are envisaged to percolate into the SCLM from slabs of oceanic crust that - are subducted underneath the continents. - - 2020-01-31, ongoing project - - - 2018-02-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-RI - RI – Reintegration panel - - - Germany - - - SalFluMa - - - H2020-MSCA-IF-2016 - - - 746518 - - - - - UNIVERSITEIT VAN AMSTERDAM - UNIVERSITEIT VAN AMSTERDAM - - - EUR 2 000 000 - - - Quantifying Quantum Gravity Violations of Causality and the Equivalence Principle - - - EUR 2 000 000 - - - Netherlands - Netherlands - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Quantum gravity must violate at least one of three principles at the foundations of physics: unitarity, causality, or the equivalence principle. Recent theoretical work on black holes has shown that such violations are not - limited to extremely short distances, where quantum gravity effects are expected, but also occur at distances much larger than the Planck scale. This work has revealed a huge gap in our understanding: we have no working criterion for when quantum - gravity violations of the usual laws of physics are important. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Netherlands - - - QUANTIVIOL - - - ERC-2016-COG - - - 725977 - - - - - THE HEBREW UNIVERSITY OF JERUSALEM - THE HEBREW UNIVERSITY OF JERUSALEM - - - EUR 2 000 000 - - - Elucidating the Role of Enhancer Methylation Variation in Cancer and Developing Enhancer-based Markers and Targets for Precision Medicine - - - EUR 2 000 000 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Cancer is a growing medical problem which genetic and environmental basis is not clearly understood. Massive efforts over the last decade have identified differences in cancer gene expression that cannot be explained by coding - sequences or promoter variations, whereas the effect of transcriptional enhancers remains unclear due to the lack of an effective way to link enhancers with their controlled genes. Recently, we discovered a class of inter-tumor, inter-patient DNA - methylation variations in putative enhancers that predict changes in gene expression levels with much greater power than promoter or sequence analyses. The overall goal of this proposal is to determine if changes in enhancer methylation form part of - the genomic basis of cancer. Our aim is to elucidate methylation-influenced disease regulatory circuits that affect cancer driver and risk genes and may ultimately serve as markers for disease progression and drug response. Utilizing a new genomic - methodology, which allows systematic prediction and verification of gene-enhancer pairing, I will test the above hypothesis in two disease models: breast cancer and glioblastoma. I will methodologically assess numerous potential enhancers across the - disease genomes and explore the effects of genetic and epigenetic mutations and variations at these sites. Informative sites will then be evaluated as markers of gene expression level in tumor biopsies. Ultimately, I will apply novel tools to - manipulate selected enhancers genetically and epigenetically, thus investigating the causal relationships between enhancer methylation and gene expression, and assessing the potential for tuning gene expression levels by enhancer methylation - modification. This study may transform our understanding of the mechanisms underlying disease predisposition, determine the regulatory circuits of key disease genes, lead to improved diagnosis and predictive abilities, and may pave the way for - precision epigenetic therapy. - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Israel - - - ONCOmetENHANCERS - - - ERC-2016-COG - - - 724803 - - - - - UNIVERSITE DE RENNES I - UNIVERSITE DE RENNES I - - - EUR 1 415 506 - - - Fluorescent-based innovative measure in thin liquid films: A way to understand stability and energy dissipation in foams and emulsions - - - EUR 1 415 506 - - - France - France - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Nobody knows why a soap bubble collapses. When the liquid film forming the bubble, stabilised by surfactants, becomes too thin, it collapses. This seemingly simple problem, ruled by the classical laws of fluid mechanics and of - statistical physics, is still a challenge for the physicist. The rupture criteria based on a stability analysis in the vicinity of the film equilibrium state fail to reproduce the observations. However the film ruptures in a foam obey some simple - phenomenological laws, which suggest that underlying fundamental laws exist and wait to be determined. The state-of-the-art conjecture is that ruptures are related to hydrodynamical processes in the films, a field in which I have now an international - leadership. Recent experimental data I obtained open the possibility to address this question using a fully non-linear approach in the far from equilibrium regime. In this aim, DISFILM will develop an innovative technique to measure the interface - velocity and surfactant concentration, based on the use of fluorescent surfactants. The risk relies in the adaptation to dynamical conditions of advanced optical techniques. These quantities have never been measured on flowing interfaces yet, and my - technique will be an important breakthrough in the field of free interface flows in presence of surfactants. A set-up will be designed to reproduce on few thin films the deformations occurring in a foam sample. The dynamical path leading to the - rupture of the film will be identified and modelled. The results obtained on an isolated film will be implemented to predict the 3D foam stability and the approach will be extended to emulsions. Foams and emulsions are widely used in industry and - most of the stability issues have been solved. Nevertheless, most of the industrial formulations must currently be modified in order to use green surfactants. This adaptation will be extremely more efficient and possible with the results of DISFILM - as a guideline. - - 2022-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - France - - - DISFILM - - - ERC-2016-COG - - - 725094 - - - - - KATHOLIEKE UNIVERSITEIT LEUVEN - - - EUR 172 800 - - - Microbes in the city: a metagenomic trait-based analysis of microbial metacommunity structure along urbanization gradients - - - EUR 172 800 - - - Belgium - - - Higher or Secondary Education Establishments - - Human induced environmental gradients have a strong effect on biodiversity and ecosystem functioning. Despite the valuable ecosystem services (such as biogeochemical cycling and xenobiotic degradation) provided by microbial - communities, environmental conservation policies usually neglect microbial diversity. This can be in part attributed to our poor understanding of microbial community responses to anthropogenic influences in natural landscapes. Urban ecosystems are - key examples of environments that are strongly impacted by anthropogenic activity. In addition to our need to understand how microbial communities respond to urbanization, urbanization gradients are also excellent model systems to study how the - taxonomic and functional diversity and composition of microbial communities respond to anthropogenic stress in general. - - 2017-04-30, closed project - - - 2015-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Belgium - - - MicroCity - - - H2020-MSCA-IF-2014 - - - 655159 - - - - - UNIVERSITE DE RENNES I - - - EUR 173 076 - - - Geophysical Signature of Subsurface Reactive Mixing - - - EUR 173 076 - - - France - - - Higher or Secondary Education Establishments - - Subsurface reactive processes play a key role in dictating the evolution of subsurface environments, their interaction with surface water bodies and the migration and remediation of transported contaminants. In particular - reactive hot spots tend to concentrate in mixing fronts between fluids of different compositions, such as recently infiltrated/injected fluids and resident groundwater, which develop in a range of situations, including CO2 sequestration operations - and geothermal systems, contaminant remediation operations, and reactive hyporheic zones beneath rivers. Our understanding of the development and temporal dynamics of these hotspots is currently hampered by the limited sampling offered by boreholes. - Recent breakthroughs in geoelectrics may however profoundly change our vision of these phenomena by providing non-invasive techniques with high sensitivity to many geological processes. GeoElectricMixing will hence develop a novel approach to - investigate the temporal dynamics of reactive mixing processes from Complex Impedance and Self Potential signals. The coupling of reactive mixing and geoelectrics will be quantified and upscaled by integrating charge transport and polarization - phenomena in a new modeling framework, recently developed by the host to predict the spatial distribution of chemical species and reaction rates across mixing fronts (WP1). Dedicated experiments will then be designed by integrating electrodes in a - novel millifluidic setup to monitor jointly the temporal evolution of geoelectrical parameters and the spatial distribution of concentrations and reactions rate in a reactive mixing front progressing through the cell (WP2). GeoElectricMixing is thus - expected to open a new window on subsurface reactive mixing phenomena, expanding our capacities to detect and quantify these processes in situ, and thus providing critical data to unlock current open questions on the dynamics of mixing processes and - their role in reaction enhancement. - - 2019-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - France - - - GeoElectricMixing - - - H2020-MSCA-IF-2016 - - - 752773 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 183 454,80 - - - Mapping Nanoscale Charge Separation at Heterojunctions with Ultrafast Electroabsorption Microscopy - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Nanostructured electronic materials e.g. organic semiconductors (OSCs) and 2D semiconductors offer great promise for applications in optoelectronic (OE) devices, such as photovoltaics (PVs), light emitting diodes (LEDs) and - photodetectors. The primary photoexcitations in both OSCs and 2D semiconductors are strongly bound excitons, quasiparticles of electrons and hole bound by the Coulomb interaction. Three aspects of these materials stand out when attempting to study - photophysics of these materials. (1) Many of the crucial OE process in these systems occur at heterojunctions between p- and n-type materials, where charges recombine to form excitons and excitons dissociate to form charges. (2) The timescale for - many such process is sub-ps, and charge transfer and charge separation (CS) can occur on sub-100fs timescales. (3) thin films made of these materials possess spatial inhomogeneity on µm and sub-µm length scales, due to variations in molecular - packing, crystallinity and phase segregation in OSCs and due to lattice defects and variation in surface passivation and strain in 2D materials. No currently available technique has the ability to spatially correlate transient spectroscopic data with - local molecular structure and composition. In order to do this, we will develop a new platform to directly image CS with sub-10fs time-resolution with sub-µm spatial resolution. Recent advances in pump-probe microscopy and ultrafast - Electro-Absorption (EA) spectroscopy in the host’s group will be combined with the applicant’s expertise with optical microscopes and advanced data analysis methods to detect and quantify inhomogeneity. Novel analysis methods combined with an - ultrafast EA pump-probe microscopy will allow for correlation of transient spectroscopic data with local molecular structure and composition. This will lead us to elucidate how CS is controlled by local properties such as molecular packing and - crystallinity in OSCs and defect sites etc. in 2D semiconductors. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - NanoEAscopy - - - H2020-MSCA-IF-2016 - - - 748050 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 269 857,80 - - - Linguistic Illusions in Children with Down Syndrome, Specific Language Impairment and Typical Language Development - - - EUR 269 857,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - This project investigates the acquisition of grammar in children with Down syndrome (DS), Specific language Impairment (SLI) and typical language development (TLD) between the ages of 2 and 12, speaking African American - Vernacular English (AAVE) and Southern English (SE). Similarities and differences will be compared between the three populations to determine whether the reduced use of inflectional marking in AAVE speaking children is the result of linguistic - illusions, conditioned by factors external to morphosyntax (i.e dialectal particularities). - - - 2020-08-20, ongoing project - - - 2017-08-21 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - United Kingdom - - - LINGUISTIC ILLUSIONS - - - H2020-MSCA-IF-2016 - - - 749360 - - - - - LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN - - - EUR 171 460,80 - - - Prebiotic Synthesis of Pyrimidine Nucleosides: New Insights into RNA Evolution - - - EUR 171 460,80 - - - Germany - - - Higher or Secondary Education Establishments - - Understanding how life evolved on Earth is widely regarded as one of the most formidable challenges in modern science. The exploration of the mechanisms regarding the origin of life not only expands our understanding of - natural sciences, but also provides new clues regarding the search for life forms and Earth-like conditions on planets other than our own. Ribonucleic acid (RNA) is widely regarded by the scientific community as the key molecule that gave rise to the - origin of life. In order to support this “RNA World” hypothesis, scientists over the years have attempted to replicate the conditions present on the early-earth to afford nucleosides in a prebiotic manner. The lack of a uniform synthetic pathway - affording canonical purine and pyrimidine nucleosides as well as non-canonical ones impedes our deeper understanding of the early evolution of RNA. Moreover, what has not been investigated in detail is the occurrence of a more primitive prebiotic - molecule that might have evolved into RNA over the millennia. In this project, Dr. Okamura aims to study the prebiotic emergence of pyrimidine and pyrimidine-like nucleosides by developing a novel cyanoacetylurea pathway. This is expected to provide - canonical as well as non-canonical pyrimidines under prebiotically plausible conditions. Using similar principles, novel pseudo-cyclic pyrimidines, inspired by the aforementioned pathway, will also be synthesized in order to examine their potential - validity as candidates for primitive RNA. This project will provide new insight into the evolution of RNA as well as a deeper understanding of the origin of life. Moreover, it will aim to inspire novel approaches towards the European space - exploration programs for the search of Earth-like conditions as well as life forms on other planets. This multidisciplinary field, where astrobiology meets prebiotic and nucleic acid chemistry will inspire and offer unique training to Dr. Okamura - enabling him to embark on his own academic career. - - 2019-05-31, ongoing project - - - 2017-06-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Germany - - - PRENUCRNA - - - H2020-MSCA-IF-2016 - - - 752420 - - - - - THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE - - - EUR 183 454,80 - - - Effectiveness of Terrestrial Protected Areas in Reducing Human Pressure - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Human impacts on nature have led to massive biodiversity declines. Protected areas (PAs) have been suggested as one of the most important tools to reduce human pressure and protect biodiversity. In this project I will advance - our understanding of the effectiveness of terrestrial PAs in reducing human pressure and improve current knowledge on how to measure human pressure, by specifically addressing three objectives: 1) To understand how management quality affects PAs - ability to reduce human pressure, 2) To reconciling remote sensed maps of human pressure with field observation of the impact of human threats, and 3) To improve existing maps of human pressure by including data of key threats to biodiversity (e.g. - natural resource use and invasive species). The foundation of the project will be the Temporal Human Pressure Index (e.g. a temporal Human Footprint), the World Database of Protected Areas, and a global database on Management. The three objectives - will apply different state-of-the-art statistical approaches including propensity matching and general linear mixed effects models to achieve these ambitious objectives. The project is expected to lead to three high impact peer-reviewed papers as - well as min two popular science papers, and one policy brief. The project will help me develop new data and skills instrumental to achieving my career goals in academia after the fellowship. I will be hosted in the conservation group at the - University of Cambridge, under supervision of Professor Andrew Balmford who is one of the world’s leading conservation scientist and an expert on how to understand human pressure in relation to biodiversity. Professor Neil Burgess will be my - supervisor while seconded at WCMC. He is a world leading expert on management effectiveness and has years of experience working on pressure and PAs. This proposal represents a frontier in conservation science and is of very high relevance to the EU - and global conservation policy. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - PRESSURE - - - H2020-MSCA-IF-2015 - - - 706784 - - - - - TEL AVIV UNIVERSITY - TEL AVIV UNIVERSITY - - - EUR 2 000 000 - - - Stability and dynamics at different spatial scales: From physiology to Alzheimer's degeneration - - - EUR 2 000 000 - - - Israel - Israel - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - How neuronal circuits maintain the balance between stability and plasticity in a constantly changing environment remains one of the most fundamental questions in neuroscience. Empirical and theoretical studies suggest that - homeostatic negative feedback mechanisms operate to stabilize the function of a system at a set point level of activity. While extensive research uncovered diverse homeostatic mechanisms that maintain activity of neural circuits at extended - timescales, several key questions remain open. First, what are the basic principles and the molecular machinery underlying invariant population dynamics of neural circuits, composed from intrinsically unstable activity patterns of individual neurons? - Second, is homeostatic regulation compromised in Alzheimer's disease (AD) and do homeostatic failures lead to aberrant brain activity and memory decline, the overlapping phenotypes of AD and many other distinct neurodegenerative disorders? And - finally, how do homeostatic systems operate in vivo under experience-dependent changes in firing rates and patterns? - - - 2022-09-30, ongoing project - - - 2017-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - Israel - - - MacroStability - - - ERC-2016-COG - - - 724866 - - - - - BCBL BASQUE CENTER ON COGNITION BRAIN AND LANGUAGE - - - EUR 158 121,60 - - - The time-course of visual, orthographic, phonological and semantic information during written word processing in skilled deaf readers: evidence from eye movements and ERPs - - - EUR 158 121,60 - - - Spain - - - Research Organisations - - Learning to read is a great challenge for deaf children due to their limited access to the sounds andlimited knowledge of the language they learn to read. Deaf adults’illiteracy levels aremuch higher than that of their hearing - peers, but some deaf individuals can and do become skilled readers, though in a qualitatively different way than typically observed in hearing readers. New evidence shows that relative to skilled hearing readers (SKH), deaf readers do not activate - phonological codes, but activate orthographic codes and show greater use of semantic informationduring word reading. Eye movement data shows that skilled deaf readers (SKD) skip words more often, and refixate words less often than SKHreaders do. In - other words, SKDreaders are more efficient at processing words accurately within a single fixation than SKHreaders are, and this may be in part explained by 1) faster processing of visual information, 2) more direct connections between orthography - and semantics, or 3) a combination of these two factors. This has been termed the word processing efficiency (WPE) hypothesis and the hypothesis predicts that SKD readers will show earlier activation of orthographic codes, no phonological activation, - and thus faster access to semantic codes compared to SKH readers. I will test this hypothesis by investigating and comparing the time-course of word processing in SKDand SKHreaders, by 1) observing participants’ eye movements during reading to - determine the earliest point of activation of parafoveal visual, orthographic, phonological, and semantic codes, and 2)assessing the neural underpinnings of the WPE hypothesis with respect to the timing and types of codes with ERP measures. The - results will lead to empirically tested solutions for the reading development of deaf children that are not based on how reading develops in children who can hear and will lead to more effective reading instruction for deaf children to increase their - functional literacy. - - 2019-04-30, Grant Agreement terminated - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Spain - - - TIME COURSE - - - H2020-MSCA-IF-2015 - - - 704005 - - - - - THE UNIVERSITY OF EXETER - - - EUR 195 454,80 - - - Regulating Umbilical Cord Blood Biobanking in Europe - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The research proposed for this fellowship is a study of the establishment of national and European regulation on Umbilical Cord Blood (UCB) biobanking in a comparative perspective (the UK, Germany, France, Italy and Spain) and - with an in-depth analysis of the implementation of regulation in the everyday practice of UCB practi-tioners, through a bi-national comparison in the UK and Italy. The first scientific aim is to offer an empirically grounded understanding of how - regulations and their practical implementation influence the conducting of biosci-entific research and shape the structuring of different bioeconomy regimes in UCB science and clinical applica-tion. The second scientific aim is to contribute to the - field of Science and Technology Studies (STS) by develop-ing an analytical approach combining macro-analysis on policy-making and regulations with meso- and micro-level analyses on the practical accomplishment of enacting regulations in everyday - research practices, for offering a more comprehensive understanding of governance and policy-making in the field of biomedicine which inte-grate the role of structural factors with that of the agency of actors involved. Given the importance assigned - by the European Union to the development of stem cell research and the coordination of biobanks, the proposed research aims also to offer useful policy suggestions for improving the harmonization and optimization of the EU circuit of supply of UCB - units for biological research and medical applications. I will diffuse to practitioners and regulators the findings of the research related to the comparative analysis on national regulations, on the ways in which these interact with the EU - directives and on how practitioners manage and enact compliance with national regulations, international directives and the exigencies of the global circulations of biomedical objects, standards, and proto-cols in biobanking. - - 2017-09-30, Grant Agreement terminated - - - 2015-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - REGUCB - - - H2020-MSCA-IF-2014 - - - 657361 - - - - - JOHN INNES CENTRE - JOHN INNES CENTRE - - - EUR 2 749 962 - - - Quantitative analysis of DNA methylation maintenance within chromatin - - - EUR 2 749 962 - - - United Kingdom - United Kingdom - - - Research Organisations - Research Organisations - - Cytosine methylation is a chemical modification that is precisely copied when DNA is replicated. Because methylation can regulate gene expression, accurate reproduction of DNA methylation patterns is essential for plant and - animal development and for human health. The enzymes that maintain DNA methylation have to work within chromatin, and particularly to contend with nucleosomes – tight complexes of DNA and histone proteins. How methylation of nucleosomal DNA is - maintained remains unknown, and even the simple matter of whether nucleosomes hinder or promote methylation is controversial. - - 2022-03-31, ongoing project - - - 2017-04-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-2016-COG - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - MaintainMeth - - - ERC-2016-COG - - - 725746 - - - - - UNIVERSITEIT UTRECHT - - - EUR 177 598,80 - - - New generation of chimeric TLR2-NOD agonist compounds for vaccine adjuvants - - - EUR 177 598,80 - - - Netherlands - - - Higher or Secondary Education Establishments - - New vaccine modalities need to be developed that can activate more potently the immune system, in this regard, adjuvants augment adaptive immune responses and can improve vaccine performance. Aluminium salt (alum) is the most - commonly used adjuvant for human vaccination. However, it drives primarily TH2-effector responses and is not effective for vaccines that target mucosal surfaces. Thus, safe and potent adjuvants need to be developed that can increase and direct - vaccine-specific immunity. Recent advances in our understanding of innate immune responses are providing opportunities to design better adjuvants. The innate immune system senses microbes through pattern-recognition receptors (PPRs), which include - the Toll-like receptors (TLRs), and intracellular NOD-like receptors (NLRs) and C-type lectin-like (CTLs) receptors that are expressed by immune cells. Activation of these receptors leads to the production of cytokines that provide early defences - during infection. Cytokines also regulate adaptive immunity by controlling the quantity and quality of B and T cell activation, which in turn results in protective immune responses to pathogens. Pathogen-associated molecular patterns (PAMPs) such as - lipopolysaccharides, lipopeptides, and peptidoglycan fragments can activate PPRs and are attractive compounds for the development of new adjuvant. Although during microbial infection many different PRRs are activated, almost all adjuvants that are - being developed rely on the stimulation of a single PRR. In this project, we propose that compound adjuvants derived by the covalent linking of two PAMPs (fusion PAMPs), for example, TLR2 and NOD agonists, will ensure that immune cells are being - exposed to both, resulting in efficient cross talk of signal transduction pathways and in synergistic immune activation. If so, chimeric immune modulators (fusion PAMPs) can be employed at lower adjuvant concentrations, thereby minimizing unwanted - side effects. - - 2019-04-30, ongoing project - - - 2017-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - Netherlands - - - FusionPAMPs - - - H2020-MSCA-IF-2016 - - - 749719 - - - - - THE UNIVERSITY OF BIRMINGHAM - - - EUR 183 454,80 - - - Algorithmic Containment of Threats in Graphs, Networks or Webs - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The project is about the security of networks, and how to select the best containing actions to perform when a network is threatened. Network security is a major concern for Europe in the guise of at least three threats: - attacks on computer networks and related infrastructure; diseases spreading in networks consisting of people, livestock, crops or wildlife; and the spread of fires in forests or buildings. The project brings together an experienced researcher with a - successful track record in “the firefighter problem” (which models the general network security problem), a supervisor with complementary expertise and world-leading research record in multi-objective optimization, a host organization with expertise - and leading research groups in (i) Security, (ii) Randomized, heuristic optimization (from theory to industrial exploitation) and (iii) Human-Computer Interaction. Two non-academic secondment partners strengthen this team still further, bringing in - industry-scale optimization experience (Noesis Solutions), and a long track record of advising for fire safety to major infrastructure projects including to the military (Lee Anderson). The experienced researcher will use the training and mobility - afforded by this complementary partnership to further the impact of his research on European security, benefit from skills training in industrial exploitation and on offering policy advice, and learn a range of additional academic and non-academic - skills from participating in the training of young researchers. Scientific results of the project include new, effective computational methods achieving better results in practical applications mentioned above. Theoretical understanding of spreading - emergencies in graphs will be useful in fundamental research in other fields, for example, in medicine in research aimed at utilizing the knowledge about contacts in the population for understanding how disease traits (such as the transmission rate - and the infectious period) evolve. - - 2018-09-11, Grant Agreement terminated - - - 2016-09-12 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ACTING-NOW - - - H2020-MSCA-IF-2015 - - - 704330 - - - - - UNIVERZITA KARLOVA - - - EUR 142 720,80 - - - Ecological Modelling of the Greenland Ice Sheet Surface Ecosystem - - - EUR 142 720,80 - - - Czech Republic - - - Higher or Secondary Education Establishments - - Glaciers and ice sheets contain distinct ecosystems and are very vulnerable to the ongoing climate change, with potentially significant impacts. However, predictions of future glacier ecosystem change are virtually impossible - due to the lack of a theoretical framework of glacier and ice sheet ecosystems that would enable their mathematical modelling. The principal aims of the proposed fellowship are to provide a theoretical framework of the microbe-dominated supraglacial - (glacier surface) ecosystem of the Greenland Ice Sheet and to develop a tool for prediction of the future change of the ecosystem, and to establish the Greenland Ice Sheet as a model ecosystem for studying microbial biogeography and diversity - patterns. This will be achieved through developing a conceptual model of the system, its mathematical formulation, verification and validation, and subsequent simulations of future climatic scenarios. Furthermore, a sampling strategy will be - developed allowing direct testing of relevant ecological hypotheses such as the diversity-productivity relationship. A two-way knowledge transfer is a key feature of this project: The Fellow will take advantage of the expertise of the Supervisor and - the Department in ecological theory and modelling, while transferring his knowledge of glaciers as microbe-dominated ecosystems to the Department. - - 2017-12-31, closed project - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Czech Republic - - - EMoGrIS - - - H2020-MSCA-IF-2014 - - - 657533 - - - - - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - MOSAIQUES DIAGNOSTICS GMBH - IDRYMA IATROVIOLOGIKON EREUNON AKADEMIAS ATHINON - EMERGENTEC BIODEVELOPMENT GMBH - HYBRIDSTAT PREDICTIVE ANALYTICS OE - - - EUR 387 000 - - - PRoteome-based assessment of vascular disease for the Establishment of a Translational REsearch plATform - - - EUR 387 000 - - - France - Germany - Greece - Austria - Greece - - - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Research Organisations - Private for-profit entities (excluding Higher or Secondary Education Establishments) - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Cardiovascular disease (VD) is the leading cause of mortality and morbidity in Europe and worldwide. The objective of the PRETREAT consortium is to generate a joint SME/academic European preclinical platform for providing - services for detection of VD and drug development. This platform will combine the use of urinary and/or blood peptidomics in humans and in preclinical animal models of VD, together with bioinformatics and systems biology, in order to better detect, - stratify and decipher the molecular mechanisms of VD, develop new animal models with high similarity to human disease, and provide new tools for obtaining information on novel drug targets. - - 2019-12-31, Grant Agreement terminated - - - 2016-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.3."> - - - MSCA-RISE-2015 - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) - - - France - - - PRETREAT - - - H2020-MSCA-RISE-2015 - - - 690966 - - - - - HERIOT-WATT UNIVERSITY - - - EUR 183 454,80 - - - ANALYSIS OF RC STRUCTURES EMPLOYING NEURAL NETWORKS - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The primary objective of the proposed project is to develop a radically new structural analysis procedure capable of accurately predicting the nonlinear behaviour of reinforced concrete structures. The proposed approach will - be developed within the Soft Computing framework and as a result will require significantly less computational resources than those of more traditional methods of structural analysis. The proposed procedure will simulate each RC element, the - beam-column joints included, with a single neural network, which has first to be appropriately trained. The training process will be based on the combined use of published test data, numerical predictions obtained from nonlinear finite-element - analyses and the predicted behaviour of published physical models of RC structural elements at their ultimate limit state. In order to model intricate structures, the individual Neural Networks will be combined through a new solution strategy so as - to provide a representative model of the structure considered. The stability and robustness of the proposed structural analysis method, as well as the validity and objectivity of its predictions, will be ensured through a comparative study of the - predicted behaviour of RC frames with its counterparts established experimentally and numerically via nonlinear finite element analysis. Throughout these studies, attention will be focussed on identifying parameters affecting the overall structural - response of RC frames (such as the effect of crack-formation within the joint regions) as well as their implications on practical structural analysis and design. Overall, the proposed work will lead to a stable, robust and computationally efficient - numerical procedure capable of realistically and objectively predicting the nonlinear response of RC structures and suitable, not only for research and practical applications, but also for solving design optimization and reliability problems which - require extensive parametric investigations. - - 2017-08-31, closed project | - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ARCSENN - - - H2020-MSCA-IF-2014 - - - 660545 - - - - - ANKARA UNIVERSITESI - ANKARA BUYUKSEHIR BELEDIYE BASKANLIGINA - - - EUR 131 260 - - - Life is Science, Science is Life: LET'S DO THE SCIENCE! - - - EUR 353 525 - - - Turkey - Turkey - - - Higher or Secondary Education Establishments - Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) - - Through the project, it is aimed to show public that researchers are most likely with them. They work in a wide range of topic but the common base for all areas is scientific point of view. It is planned to organize an event - including at least 200 different interactive scientific activities from wide range of scientific disciplines, opening universities laboratories to public, organizing number of meetings and workshops, conferences, edutainment facilities, seminars and - entertainment activities related to science subjects, observing and discussing ideas of public about science and hot topics of their life related to science and EU. - - - 2015-11-30, closed project - - - 2014-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.5."> - - - MSCA-NIGHT-2014 - European Researchers' Night (NIGHT) - - - CSA - Coordination and support action - - - Turkey - - - Let's Do The Science - - - H2020-MSCA-NIGHT-2014 - - - 633256 - - - - - UNIVERSITAET HAMBURG - THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - - - EUR 239 860,80 - - - Room temperature stabilization and all-electrical manipulation of chiral spin structures in metallic multilayers - - - EUR 239 860,80 - - - Germany - United States - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - The constantly increasing energy consumption associated with the functioning of micro-electronic devices calls for the design of more energy efficient technologies. While semiconductor technologies have reached their intrinsic - limitations, spintronics offers a new path towards the design of memory and logic devices with high density and low power consumption. However, present spintronic devices such as magnetic-RAMs still suffer from high current density requirements. - - - 2020-12-31, ongoing project - - - 2018-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-GF - Global Fellowships - - - Germany - - - SKDWONTRACK - - - H2020-MSCA-IF-2016 - - - 748006 - - - - - THE UNIVERSITY OF BIRMINGHAM - - - EUR 195 454,80 - - - Epigenetic mechanisms underlying the influence of paternal drug experience on offspring behavior - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - The idea of transmitting paternal environmental impact across generations has been indicated and described in studies across species, but the mechanism is still unclear. The overall aim of the project is to test whether - H3K27me3, a type of epigenetic modification on histone 3 [1], is involved in transmitting environmental impact across generation to influence the behavior of offspring. With a behavioral neuroscience background, the experienced research (ER) will - apply his expertise in high throughput behavioral assay and combine techniques he will learn from the host lab, including epigenetic profiling, NGS, targeted epigenome editing and computational analysis to address specifically whether paternal drug - experience influence offspring behavior via modifying H3K27me3 on dopamine-related genes that are involved in various behaviors [2]. Besides advancing our understanding of the importance and mechanism of paternal inheritance and the role of - epigenetics in general, this project will also further extend zebrafish as a model in studying cross-generational transmission of environmental experience by combining multidisciplinary techniques. The trainings ER will be beneficial and essential - for his future goal to study epigenetic mechanisms underlying physiology and pathology of brain. - - 2019-02-28, Grant Agreement terminated | - - - 2017-03-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2016 - Individual Fellowships - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - EPOFFSPRING - - - H2020-MSCA-IF-2016 - - - 753976 - - - - - UNIVERSITA DEGLI STUDI DI FERRARA - - - EUR 168 277,20 - - - Neotithic transition in the Iberian Peninsula: reviewing an old question from new technological and computational genome wide approaches - - - EUR 168 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - The research goal of this proposal revolves around a widely debated topic in archaeology, anthropology and population genetics: the dynamics of the spread of farming into Europe, or Neolithic transition. For a long time, this - key event that was to define modern Europeans has fuelled a dichotomic research debate. In short, did the Neolithic spread into Europe as the result of cultural or demographic diffusion? While many approaches can be attempted, in the last few years, - ancient DNA (aDNA) studies have strongly contributed to shedding light on this topic, through the recovery and analysis of an increasing number of mitochondrial and nuclear genomes from prehistorical human samples. Far from closing the debate, these - palaeogenomes are revealing a more complicated scenario, where the times, paths and genetic legacy of the Neolithic diffusion seem to have been different in different geographic areas. Furthermore, as the genomic data increase, the aDNA field is soon - facing the challenge of evolving from a research area largely based on technical development for the recovery of short DNA fragments, to the analysis of larger datasets (ultimately, whole genome data) in the context of human population genetics. - - 2017-08-31, closed project - - - 2015-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - NeoGenHeritage - - - H2020-MSCA-IF-2014 - - - 655478 - - - - - UNIVERSITA DEGLI STUDI DI FERRARA - - - EUR 168 277,20 - - - Advanced devices for the Reduction of CArbon DIoxide and Artificial photosynthesis - - - EUR 168 277,20 - - - Italy - - - Higher or Secondary Education Establishments - - The ARCADIA project will focus on building artificial photosynthetic devices (or photoelectrochemical cells), with the aim of producing alternative fuels exploiting renewable energy sources (namely sunlight). The key strategy - will involve the development of photoelectrodes able to perform the water oxidation (at the anode) and the carbon dioxide reduction (at the cathode), and their further assembly in a standalone set-up (i.e. requiring no other energy source, but - sunlight). Thus, ARCADIA will contribute to the abatement of the atmospheric anthropogenic emissions of the greenhouse gas CO2 by its exploitation as a renewable carbon feedstock to obtain clean fuels and value-added chemicals as the target products. - - 2018-04-30, ongoing project - - - 2016-05-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - Italy - - - ARCADIA - - - H2020-MSCA-IF-2015 - - - 705723 - - - - - UNIVERZITA KARLOVA - UNIVERZITA KARLOVA - - - EUR 1 362 537,50 - - - Layered functional materials - beyond 'graphene' - - - EUR 1 362 537,50 - - - Czech Republic - Czech Republic - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - There is an apparent lack of non-metallic 2D-matrials for the construction of electronic devices, as only five materials of the “graphene family” are known: graphene, hBN, BCN, fluorographene, and graphene oxide – none of them - with a narrow bandgap close to commercially used silicon. This ERC-StG proposal, BEGMAT, outlines a strategy for design, synthesis, and application of layered, functional materials that will go beyond this exclusive club. These materials “beyond - graphene” (BEG) will have to meet – like graphene – the following criteria: - - - 2021-07-31, ongoing project - - - 2016-08-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Czech Republic - - - BEGMAT - - - ERC-2015-STG - - - 678462 - - - - - GOLDSMITHS' COLLEGE - GOLDSMITHS' COLLEGE - - - EUR 1 996 830 - - - Forensic Architecture: The Media Environments of Conflict - - - EUR 1 996 830 - - - United Kingdom - United Kingdom - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - - Forensic Architecture is an emergent field that refers to the presentation of architectural evidence in legal contexts. As contemporary conflicts increasingly take place within urban areas, homes and neighbourhoods become - targets and a growing number of civilian casualties occur within cities and buildings. Architectural investigation thus becomes an essential tool of conflict analysis, not only for its crucial role in the pursuit of accountability, but also because - it enables ground breaking methodological and theoretical inquiries into the context and conduct of urban conflicts. Forensic Architecture (FA), as developed by the PI, employs a novel set of research techniques to analyse violations of international - humanitarian law (IHL) and human rights (HR) as they bear upon the built environment. FA employs architecture in three distinct ways: as an object of analysis; as a method of research; and as a mode of presentation. As such FA is able to provide - unique, solid, and clear evidence about incidents that other methods of investigation cannot engage with. This proposal, Forensic Architecture: The Media Environments of Conflict (FAMEC) will further develop the field of FA in response to a set of - newly evolved challenges. These are concerned with the way in which new modes of documentation and analysis – based on social and environmental media – have shifted the relation between conflict and built spaces. Working closely with leading HR - organizations, the project will provide novel types of architectural evidence in the context of a number of high profile IHL and HR investigations, in such places as Syria, Israel/Palestine and Amazonia/Brazil. Our forensic work will be the starting - point for a set of theoretical reflections – articulated in books, articles, journal special issues, conferences and exhibitions – that will ground FA in the histories of forensics, architecture, and human rights. - - 2021-10-31, ongoing project - - - 2016-11-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-CoG-2015 - ERC Consolidator Grant - - - ERC-COG - Consolidator Grant - - - United Kingdom - - - FAMEC - - - ERC-2015-CoG - - - 682313 - - - - - GOLDSMITHS' COLLEGE - - - EUR 195 454,80 - - - The Rise of Neoliberal Feminism - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Focusing on neoliberalism's emergent feminist discourse in the UK and the US, I aim to provide a multi-dimensional theorization of this phenomenon. Two central questions inform this project: 1) Why does neoliberalism need - feminism at this particular historical juncture in order to reinforce its hegemony? and 2) How and in what ways do certain themes of feminism lend themselves to the neoliberal project? Working on the seams of feminist theory, cultural studies and - sociology, I will embark on a comparative study, examining one key but neglected site of neoliberalism's adoption of feminism: the discourse of a happy work-family balance. In order to accomplish this, I will employ a multidisciplinary methodological - approach, combining textual and discourse analysis, qualitative data analysis and intersectional theorizing. My premise is that the resurgence of the work-family balance, which is being articulated as a feminist ideal, is the site through which the - contemporary entanglement of feminism and neoliberalism is most clearly articulated. RNF therefore has four main interrelated objectives: to map the current resurgence of the work-family balance discourse in the mainstream print media in the UK and - the US; to uncover the racial and economic underpinnings of this balance discourse; to analyse the new feminist subject this discourse is creating; and, finally, to build a theoretical framework that not only helps to explain why neoliberalism needs - feminism at this historical juncture, but one that can help account for other contemporary alignments between feminism and neo-conservative and neoliberal projects in the broader European and Western context. - - 2018-08-31, ongoing project - - - 2016-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - RNF - - - H2020-MSCA-IF-2015 - - - 704010 - - - - - HERIOT-WATT UNIVERSITY - - - EUR 195 454,80 - - - Climate-resilient pathways for the development of concrete infrastructure: adaptation, mitigation and sustainability - - - EUR 195 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Climate change is one of the key challenges facing the human race in the 21st century. To respond to this challenge new approaches to sustainable development combining mitigation and adaptation, which are referred to as - climate-resilient pathways, are needed. The development of such approaches is one of the high priority areas of modern day research that will be addressed in the proposed action in the context of concrete infrastructure. The action aims to develop a - comprehensive method based on an integration of the Life-Cycle Assessment (LCA) and Life-Cycle Cost Analysis (LCCA) techniques for the evaluation of the whole life performance of reinforced concrete (RC) structures subjected to carbonation in - conditions of climate change. To achieve this both experimental studies and numerical modelling are planned to be carried out. The method will take into account both adaptation and mitigation measures and due to numerous uncertainties involved in - such analysis be based on a probabilistic approach. It will be applied to several case studies (i.e., typical RC members located in different climatic conditions) to examine the sustainability performance of different concrete types (traditional and - ‘green’ with blended cements) and repair techniques. The method and other results obtained in the action will provide strong support for decision making regarding the sustainable development of concrete infrastructure. - - 2017-08-02, closed project | - - - 2015-08-03 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - ClimatCon - - - H2020-MSCA-IF-2014 - - - 658475 - - - - - HERIOT-WATT UNIVERSITY - - - EUR 183 454,80 - - - Scattering and Amplification of fundamental photonic-hydrodynamic excitations in Kerr non-linear media - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - "Intense light beams propagating in nonlinear defocusing media behave identically to fluids. This raises the fascinating perspective of studying fluid dynamics using light. These "photon fluids" and have been shown to exhibit - remarkable properties such as superfluidity and condensation (similar to Bose-Einstein condensation). Here, we wish to use photon fluids for the creation of artificial flowing spacetime geometries otherwise thought to be the object of more complex - and less (experimentally) accessible theories such as event horizons and black holes. The advantage of photon fluids over real fluids in this context is related to the great precision with which the fluid flow is determined by controlling the spatial - phase profile of the laser beam. This will allow us for example to also include angular momentum in our black holes, something that has never been done before. In essence, we will study photon fluids with vorticity and look for novel effects - including super-radiance amplification at the expense of the rotational motion of the black hole. - - 2017-11-01, closed project - - - 2015-11-02 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - SOUNDCONE - - - H2020-MSCA-IF-2014 - - - 659301 - - - - - THE UNIVERSITY OF LIVERPOOL - - - EUR 183 454,80 - - - Exploring glycosidic neo-epitopes of degenerative hippocampal granules in aged mice and humans: implications for ageing and dementia - - - EUR 183 454,80 - - - United Kingdom - - - Higher or Secondary Education Establishments - - Ageing is the main correlate of dementia and several other neurodegenerative diseases which currently affect more than 6 million people in Europe. Molecular understanding of these brain conditions is important for their - prevention and treatment. In mice, pathological granular structures positive for periodic acid-Schiff stain have been found in the hippocampus with increasing age. The degenerative process of granule formation appears to originate in astrocytes, but - adjacent neuronal structures are affected and, accordingly, associated memory impairments have been described. Recent studies reported that granules express glycosidic neo-epitopes, a hallmark of the degenerative granule formation process. This - neo-epitope has additionally been found in Lafora bodies of a mouse model of Lafora disease, a fatal neurodegenerative condition. On the other hand, mice serum contains natural IgM antibodies that recognise the glycosidic neo-epitope, suggesting a - potentional removal mechanism. In this project, I aim to describe the structure of the glycosidic neo-epitopes of the hippocampal granules as well as the composition of the degenerative granules and Lafora bodies. To achieve these goals, I will - employ a multidisciplinary approach exploiting glycomics and neurobiology, with the application of leading-edge technologies that include histological methods, analytical techniques, MALDI-MS imaging and laser-capture microdissection. Moreover, the - binding patterns of the anti-neo-epitope natural IgMs will also be explored. Finally and importantly, the expression of the glycosidic neo-epitope in human brain will be assessed. Overall, the knowledge generated will provide new data on brain - degenerative processes underlying age-related memory impairments in humans. Ultimately this project will generate new insights for the use of glycosidic neoepitopes as biomarkers for ageing and neurodegenerative diseases, and for prevention and - therapeutic strategies using natural antibodies. - - 2019-08-31, ongoing project - - - 2017-09-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.2."> - - - MSCA-IF-2015-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) - - - MSCA-IF-EF-ST - Standard EF - - - United Kingdom - - - GLYCONEOBRAIN - - - H2020-MSCA-IF-2015 - - - 708563 - - - - - FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA - FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA - - - EUR 1 996 250 - - - Multipoint Optical DEvices for Minimally invasive neural circuits interface - - - EUR 1 996 250 - - - Italy - Italy - - - Research Organisations - Chiara Andreoli - Tel.: +3901071781854 - Fax: +39 010 7170817 - Research Organisations - Chiara Andreoli - Tel.: +3901071781854 - Fax: +39 010 7170817 - - A primary goal of experimental neuroscience is to dissect the neural microcircuitry underlying brain function, ultimately to link specific neural circuits to behavior. There is widespread agreement that innovative new research - tools are required to better understand the incredible structural and functional complexity of the brain. To this aim, optical techniques based on genetically encoded neural activity indicators and actuators have represented a revolution for - experimental neuroscience, allowing genetic targeting of specific classes of neurons and brain circuits. However, for optical approaches to reach their full potential, we need new generations of devices better able to interface with the extreme - complexity and diversity of brain topology and connectivity. - - 2021-09-30, ongoing project - - - 2016-10-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.1."> - - - ERC-StG-2015 - ERC Starting Grant - - - ERC-STG - Starting Grant - - - Italy - - - MODEM - - - ERC-2015-STG - - - 677683 - - - - - LANCASTER UNIVERSITY - THE UNIVERSITY OF NOTTINGHAM - THE UNIVERSITY OF SHEFFIELD - UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK - III-V LAB - UNIVERSIDAD DE CADIZ - UNIVERSITE DE MONTPELLIER - UNIVERSITE MONTPELLIER 2 SCIENCES ET TECHNIQUES - UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA - PHILIPPS UNIVERSITAET MARBURG - SGENIA SOLUCIONES SL - - - EUR 3 947 500,44 - - - Postgraduate Research on Dilute Metamorphic Nanostructures and Metamaterials in Semiconductor Photonics - - - EUR 3 947 500,44 - - - United Kingdom - United Kingdom - United Kingdom - Ireland - France - Spain - France - France - Italy - Germany - Spain - - - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Research Organisations - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Higher or Secondary Education Establishments - Private for-profit entities (excluding Higher or Secondary Education Establishments) - - Photonics, nanotechnology, advanced materials, and advanced manufacturing technologies have been identified as key enabling technologies (KETs) for the EU. Today the photonics global market alone is around €300 billion and - Europe has established a strong position with a total share of 20%, directly employing about 290,000 people. However, the shortage of sufficient skilled labour and entrepreneurs capable of handling the highly multi-disciplinary nature of KETs remains - a major problem in the EU. Tailoring of semiconductors at the nanoscale is an important enabling technology for a wide range of photonics and electronics applications in diverse areas. In the training network proposed here, a cohort of 15 early stage - researchers will be trained in the full range of skills required for a career in photonics, including materials growth, device fabrication, characterisation, design, theory, and commercialisation. A carefully-chosen, well-balanced consortium of 8 - academic partners, 2 full industry partners and 7 associated partners are well placed to provide the training in these skills, with European and worldwide reputations as leaders in each field. These skills will be developed within four burgeoning - research areas; Semiconductor Metamaterials & Plasmonics, Dilute Nitride semiconductor nanostructures, Hydrogenated Semiconductors and Metamorphic structures. The outcomes of this enabling fundamental research are well focused to deliver advances - in sources for secure communications, sensitive detectors for security applications, more efficient solar cells for energy generation, LEDs and sensors for environmental gas and bio-sensing. Each researcher will experience both academic and - commercial environments thanks to the strong industrial involvement, resulting in multi-skilled, industry-focused graduates. PROMIS therefore directly addresses the need for additional skilled photonics professionals, as identified by the European - Technology Platform, Photonics21. - - 2018-12-31, ongoing project | - - - 2015-01-01 - - - <meta name="WT.cg_s" content="H2020-EU.1.3.1."> - - - MSCA-ITN-2014-ETN - Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) - - - MSCA-ITN-ETN - European Training Networks - - - United Kingdom - - - PROMIS - - - H2020-MSCA-ITN-2014 - - - 641899 - - - diff --git a/spiders/cordis_spider.pyc b/spiders/cordis_spider.pyc index 854f89ebba4ecbcb024cceb928a4d3b87091995c..2b14a42b08834e9a8bfb0b192493ad846ff5fb72 100644 GIT binary patch delta 15 Wcmew;{85;V`7&jm67 delta 15 Wcmew;{85;V`7